A0A087Y6G7_POEFO Loading...

Tetratricopeptide repeat domain 7B

AlphaFold DB , UniProt , Accession A0A087Y6G7, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 854 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M30.4Very low50.1Low229 Ų229115.9 Ų115.9100%1.12859%0.592SS**  05.90-74.1-165.8-168.700114.4
2T31.1Very low52.7Low129 Ų129112.9 Ų112.979%0.79158%0.584SS**  trans-88.7-20.9-177.938.60000114.9
3A33.8Very low55.1Low80 Ų80109.7 Ų109.766%0.66156%0.564SS**THydrogen-bonded Turntrans-79.2-21.2-177.700000115.4S6A3-S6 PolarHBondContact O-OG 2.94Å; A3-S6 VanDerWaalsContact O-OG 3.05Å
4R32.1Very low57.3Low235 Ų235102.4 Ų102.489%0.88753%0.527SS*.Hα-helixtrans-76.4-22.2178.2-92-175.6176.4173.9-1.4113.5
5K34.1Very low59.2Low157 Ų157100 Ų10068%0.68351%0.512SS*.Hα-helixtrans-86.6-18.2178.3-78.5-176.3175.1-178.80113.6S8 R9K5-S8 PolarHBondContact O-OG 2.88Å; K5-R9 WeakPolarHBondContact O-CG 3.32Å
6S40.4Very low60.8Low71 Ų7198.7 Ų98.750%0.49750%0.499SS..Hα-helixtrans-83.1-36.6178.156.20000112.4A3 R9 L10A3-S6 PolarHBondContact O-OG 2.94Å; A3-S6 VanDerWaalsContact O-OG 3.05Å; S6-R9 PolarHBondContact O-N 3.15Å; S6-L10 PolarHBondContact O-N 3.2Å; S6-L10 VanDerWaalsContact O-N 3.08Å
7G50.7Low62.3Low22 Ų2292.9 Ų92.923%0.22747%0.47CS..Hα-helixtrans-60.2-44.8176.700000113.1R9 L10 E11G7-R9 VanDerWaalsContact C-N 3.28Å; G7-R9 PolarHBondContact O-N 3.19Å; G7-L10 PolarHBondContact O-N 3.44Å; G7-E11 WeakPolarHBondContact O-CG 3.49Å; G7-E11 PolarHBondContact O-N 3.12Å
8S64.1Low63.7Low65 Ų6588.3 Ų88.346%0.45545%0.446SS..Hα-helixtrans-67.2-26.5178.267.20000113.6K5 T12K5-S8 PolarHBondContact O-OG 2.88Å; S8-T12 VanDerWaalsContact O-CG2 3.24Å; S8-T12 WeakPolarHBondContact O-CG2 3.44Å; S8-T12 PolarHBondContact O-N 3.25Å; S8-T12 PolarHBondContact O-OG1 2.9Å; S8-T12 VanDerWaalsContact O-OG1 3.13Å
9R73.8Confident64.8Low188 Ų18884.8 Ų84.871%0.70943%0.431SS*.Hα-helixtrans-79.9-37.6177.3-74.6-179.1177-174.8-2.3112K5 S6 G7 T12 E13K5-R9 WeakPolarHBondContact O-CG 3.32Å; S6-R9 PolarHBondContact O-N 3.15Å; G7-R9 VanDerWaalsContact C-N 3.28Å; G7-R9 PolarHBondContact O-N 3.19Å; R9-T12 WeakPolarHBondContact CA-OG1 3.33Å; R9-T12 PolarHBondContact O-OG1 3.29Å; R9-E13 PolarHBondContact O-N 3.48Å
10L81Confident65.7Low22 Ų2282.9 Ų82.912%0.11542%0.42CS..Hα-helixtrans-68.4-43.4176.8-176.464.2000111S6 G7 T12 E13 I14 L29 Q32 L33S6-L10 PolarHBondContact O-N 3.2Å; S6-L10 VanDerWaalsContact O-N 3.08Å; G7-L10 PolarHBondContact O-N 3.44Å; L10-T12 PolarHBondContact O-N 3.03Å; L10-E13 PolarHBondContact O-N 3.27Å; L10-I14 HydrophobicContact CG-CD1 4.13Å; L10-I14 WeakPolarHBondContact O-CG1 3.41Å; L10-I14 PolarHBondContact O-N 3.25Å; L10-L29 HydrophobicContact CD1-CB 4.34Å; L10-L29 HydrophobicContact CD1-CD2 3.84Å; L10-Q32 HydrophobicContact CD1-CB 4.23Å; L10-Q32 HydrophobicContact CD2-CB 3.98Å; L10-Q32 WeakPolarHBondContact CD2-O 3.4Å; L10-L33 HydrophobicContact CD2-CD2 4.06Å; L10-L33 HydrophobicContact CD2-CG 4.13Å
11E79.3Confident66.5Low77 Ų7780.2 Ų80.236%0.3641%0.413SS..Hα-helixtrans-58-46174.1-73.2171.1-170.600111.4G7 E13 I14 E15G7-E11 WeakPolarHBondContact O-CG 3.49Å; G7-E11 PolarHBondContact O-N 3.12Å; E11-E13 VanDerWaalsContact C-N 3.32Å; E11-E13 PolarHBondContact O-N 3Å; E11-I14 PolarHBondContact O-N 2.99Å; E11-E15 WeakPolarHBondContact O-CG 3.25Å; E11-E15 PolarHBondContact O-N 3.37Å
12T82.1Confident69.1Low80 Ų8071 Ų7149%0.49137%0.367SS..Hα-helixtrans-65.1-33176.752.90000113.5S8 R9 L10 R16S8-T12 VanDerWaalsContact O-CG2 3.24Å; S8-T12 WeakPolarHBondContact O-CG2 3.44Å; S8-T12 PolarHBondContact O-N 3.25Å; S8-T12 PolarHBondContact O-OG1 2.9Å; S8-T12 VanDerWaalsContact O-OG1 3.13Å; R9-T12 WeakPolarHBondContact CA-OG1 3.33Å; R9-T12 PolarHBondContact O-OG1 3.29Å; L10-T12 PolarHBondContact O-N 3.03Å; T12-R16 VanDerWaalsContact O-CB 3.27Å; T12-R16 WeakPolarHBondContact O-CB 3.44Å; T12-R16 PolarHBondContact O-N 3.26Å
13E83.9Confident71.8Confident71 Ų7166.5 Ų66.533%0.33234%0.336SS..Hα-helixtrans-72.8-37.2176.4-170.964.8-167.500111.1R9 L10 E11 R16 C17 L29R9-E13 PolarHBondContact O-N 3.48Å; L10-E13 PolarHBondContact O-N 3.27Å; E11-E13 VanDerWaalsContact C-N 3.32Å; E11-E13 PolarHBondContact O-N 3Å; E13-R16 PolarHBondContact O-N 2.9Å; E13-C17 WeakPolarHBondContact O-CB 2.91Å; E13-C17 PolarHBondContact O-N 3.49Å; E13-C17 PolarHBondContact O-SG 3.39Å; E13-C17 VanDerWaalsContact O-SG 3.41Å; E13-L29 HydrophobicContact CG-CD1 4.23Å; E13-L29 HydrophobicContact CG-CD2 4.26Å
14I85.3Confident74.3Confident8 Ų868.5 Ų68.54%0.04134%0.335CS..Hα-helixtrans-61.7-49.9172.3-70166.9000110.1L10 E11 R16 C17 R18 L29 L33 L47L10-I14 HydrophobicContact CG-CD1 4.13Å; L10-I14 WeakPolarHBondContact O-CG1 3.41Å; L10-I14 PolarHBondContact O-N 3.25Å; E11-I14 PolarHBondContact O-N 2.99Å; I14-R16 VanDerWaalsContact C-N 3.27Å; I14-R16 PolarHBondContact O-N 3.24Å; I14-C17 PolarHBondContact O-N 3.4Å; I14-R18 HydrophobicContact CG2-CG 4.48Å; I14-R18 WeakPolarHBondContact O-CG 3.37Å; I14-R18 PolarHBondContact O-N 3.34Å; I14-L29 HydrophobicContact CD1-CB 4.42Å; I14-L29 HydrophobicContact CG1-CB 3.86Å; I14-L29 HydrophobicContact CG1-CD1 4.11Å; I14-L33 HydrophobicContact CD1-CD1 4.32Å; I14-L33 HydrophobicContact CD1-CD2 4.29Å; I14-L33 HydrophobicContact CD1-CG 4.36Å; I14-L47 HydrophobicContact CD1-CD1 4.15Å; I14-L47 HydrophobicContact CG2-CD1 3.73Å; I14-L47 HydrophobicContact CG2-CD2 3.76Å; I14-L47 HydrophobicContact CG2-CG 4.41Å
15E85.5Confident76.9Confident66 Ų6661.8 Ų61.831%0.30831%0.313SS..Hα-helixtrans-59.1-39.5177.7-71.7-178.2176.400112.3E11 S19 Y136E11-E15 WeakPolarHBondContact O-CG 3.25Å; E11-E15 PolarHBondContact O-N 3.37Å; E15-S19 WeakPolarHBondContact O-CB 3.48Å; E15-S19 PolarHBondContact O-N 2.95Å; E15-S19 PolarHBondContact O-OG 2.96Å; E15-Y136 HydrophobicContact CB-CE1 4.22Å; E15-Y136 HydrophobicContact CG-CE1 4Å
16R84.6Confident79.4Confident79 Ų7954.3 Ų54.330%0.29828%0.28SS..Hα-helixtrans-63.3-50.1174.2-178.6-167.4169.9142.813.5111.4T12 E13 I14 R18 S19 E20T12-R16 VanDerWaalsContact O-CB 3.27Å; T12-R16 WeakPolarHBondContact O-CB 3.44Å; T12-R16 PolarHBondContact O-N 3.26Å; E13-R16 PolarHBondContact O-N 2.9Å; I14-R16 VanDerWaalsContact C-N 3.27Å; I14-R16 PolarHBondContact O-N 3.24Å; R16-R18 VanDerWaalsContact C-N 3.31Å; R16-R18 PolarHBondContact O-N 3.34Å; R16-S19 PolarHBondContact O-N 2.89Å; R16-S19 VanDerWaalsContact O-N 3.1Å; R16-E20 HydrophobicContact CG-CG 4.4Å; R16-E20 IonicContact CZ-OE1 3.65Å; R16-E20 VanDerWaalsContact CZ-OE1 3.24Å; R16-E20 IonicContact NE-OE1 3.3Å; R16-E20 PolarHBondContact NE-OE1 3.49Å; R16-E20 IonicContact NE-OE2 2.87Å; R16-E20 IonicContact NH2-OE1 3.75Å; R16-E20 PolarHBondContact NH2-OE1 2.89Å; R16-E20 IonicContact NH2-OE2 3.68Å; R16-E20 WeakPolarHBondContact O-CG 3.44Å; R16-E20 PolarHBondContact O-N 3.24Å
17C86.3Confident81.6Confident0 Ų052.6 Ų52.60%027%0.267CS..Hα-helixtrans-61.3-39179.5-76.10000112.1E13 I14 E20 G21 Q22 I26 L29E13-C17 WeakPolarHBondContact O-CB 2.91Å; E13-C17 PolarHBondContact O-N 3.49Å; E13-C17 PolarHBondContact O-SG 3.39Å; E13-C17 VanDerWaalsContact O-SG 3.41Å; I14-C17 PolarHBondContact O-N 3.4Å; C17-E20 PolarHBondContact O-N 3.23Å; C17-G21 PolarHBondContact O-N 3.19Å; C17-G21 VanDerWaalsContact O-N 3.08Å; C17-Q22 HydrophobicContact CB-CB 4.25Å; C17-Q22 PolarHBondContact O-N 3.42Å; C17-I26 HydrophobicContact CB-CD1 3.6Å; C17-L29 HydrophobicContact CB-CD1 4.26Å
18R87.8Confident83.3Confident10 Ų1057 Ų574%0.03828%0.282CS..Hα-helixtrans-62.2-42.3172.5-67.4175.476.7-172.92.2111.8I14 R16 G21 W23 I26 L47 E50 E98 Y136I14-R18 HydrophobicContact CG2-CG 4.48Å; I14-R18 WeakPolarHBondContact O-CG 3.37Å; I14-R18 PolarHBondContact O-N 3.34Å; R16-R18 VanDerWaalsContact C-N 3.31Å; R16-R18 PolarHBondContact O-N 3.34Å; R18-G21 PolarHBondContact O-N 3.3Å; R18-W23 HydrophobicContact CB-CH2 4.38Å; R18-W23 HydrophobicContact CB-CZ3 4.39Å; R18-W23 HydrophobicContact CG-CZ3 4.12Å; R18-I26 HydrophobicContact CG-CD1 4.05Å; R18-L47 HydrophobicContact CG-CD2 4.5Å; R18-E50 IonicContact CZ-OE1 2.75Å; R18-E50 IonicContact CZ-OE2 2.71Å; R18-E50 IonicContact NE-OE1 2.66Å; R18-E50 IonicContact NE-OE2 2.64Å; R18-E50 PolarHBondContact NE-OE2 3.21Å; R18-E50 IonicContact NH2-OE1 3.62Å; R18-E50 PolarHBondContact NH2-OE1 3.38Å; R18-E50 IonicContact NH2-OE2 3.04Å; R18-E50 PolarHBondContact NH2-OE2 3.35Å; R18-E98 IonicContact CZ-OE2 2.83Å; R18-E98 VanDerWaalsContact CZ-OE2 3.3Å; R18-E98 IonicContact NH1-OE1 2.6Å; R18-E98 IonicContact NH1-OE2 2.62Å; R18-E98 PolarHBondContact NH1-OE2 3.21Å; R18-E98 IonicContact NH2-OE2 2.84Å; R18-E98 PolarHBondContact NH2-OE2 3.08Å; R18-Y136 HydrophobicContact CB-CD1 4.07Å; R18-Y136 HydrophobicContact CB-CD2 4.47Å; R18-Y136 HydrophobicContact CB-CG 3.87Å; R18-Y136 VanDerWaalsContact CZ-CD2 3.49Å; R18-Y136 PolarHBondContact NH1-OH 3.11Å; R18-Y136 VanDerWaalsContact NH2-CE2 3.29Å
19S85.6Confident84.3Confident23 Ų2354.9 Ų54.916%0.16127%0.265CS..Hα-helixtrans-70.2-32.5-179.5-58.60000113.2E15 R16 G21 Y136E15-S19 WeakPolarHBondContact O-CB 3.48Å; E15-S19 PolarHBondContact O-N 2.95Å; E15-S19 PolarHBondContact O-OG 2.96Å; R16-S19 PolarHBondContact O-N 2.89Å; R16-S19 VanDerWaalsContact O-N 3.1Å; S19-G21 VanDerWaalsContact C-N 3.35Å; S19-Y136 PolarHBondContact OG-N 3.35Å
20E82.3Confident84.8Confident45 Ų4546.9 Ų46.921%0.2124%0.237CC..THydrogen-bonded Turntrans-87.7-0.8176.4-66.5179.4-177.500112.6R16 C17 Q22 L203R16-E20 HydrophobicContact CG-CG 4.4Å; R16-E20 IonicContact CZ-OE1 3.65Å; R16-E20 VanDerWaalsContact CZ-OE1 3.24Å; R16-E20 IonicContact NE-OE1 3.3Å; R16-E20 PolarHBondContact NE-OE1 3.49Å; R16-E20 IonicContact NE-OE2 2.87Å; R16-E20 IonicContact NH2-OE1 3.75Å; R16-E20 PolarHBondContact NH2-OE1 2.89Å; R16-E20 IonicContact NH2-OE2 3.68Å; R16-E20 WeakPolarHBondContact O-CG 3.44Å; R16-E20 PolarHBondContact O-N 3.24Å; C17-E20 PolarHBondContact O-N 3.23Å; E20-Q22 VanDerWaalsContact C-N 3.27Å; E20-Q22 HydrophobicContact CB-CG 4.07Å; E20-Q22 PolarHBondContact O-N 2.95Å; E20-Q22 VanDerWaalsContact OE2-CD 3.32Å; E20-Q22 PolarHBondContact OE2-NE2 3.38Å; E20-L203 HydrophobicContact CG-CD2 4.37Å
21G82.5Confident84.8Confident28 Ų2854.8 Ų54.829%0.28927%0.266SS..THydrogen-bonded Turntrans66.224-178.200000114.6C17 R18 S19 W23C17-G21 PolarHBondContact O-N 3.19Å; C17-G21 VanDerWaalsContact O-N 3.08Å; R18-G21 PolarHBondContact O-N 3.3Å; S19-G21 VanDerWaalsContact C-N 3.35Å; G21-W23 PolarHBondContact O-N 2.96Å; G21-W23 PolarHBondContact O-NE1 3.45Å
22Q85.8Confident84.9Confident35 Ų3557.1 Ų57.116%0.16428%0.277CS..  trans-84.263.6-178.9-68177.77.900111.4C17 E20 D24 K25C17-Q22 HydrophobicContact CB-CB 4.25Å; C17-Q22 PolarHBondContact O-N 3.42Å; E20-Q22 VanDerWaalsContact C-N 3.27Å; E20-Q22 HydrophobicContact CB-CG 4.07Å; E20-Q22 PolarHBondContact O-N 2.95Å; E20-Q22 VanDerWaalsContact OE2-CD 3.32Å; E20-Q22 PolarHBondContact OE2-NE2 3.38Å; Q22-D24 PolarHBondContact O-N 3.1Å; Q22-K25 HydrophobicContact CB-CD 4.4Å; Q22-K25 PolarHBondContact O-N 3.36Å
23W87.6Confident84.7Confident34 Ų3454.2 Ų54.213%0.12926%0.258CS..G310 helixtrans-63.2-27.8-173.7-54.2113000113.6R18 G21 K25 I26 P27 E50 S51 Q54R18-W23 HydrophobicContact CB-CH2 4.38Å; R18-W23 HydrophobicContact CB-CZ3 4.39Å; R18-W23 HydrophobicContact CG-CZ3 4.12Å; G21-W23 PolarHBondContact O-N 2.96Å; G21-W23 PolarHBondContact O-NE1 3.45Å; W23-K25 PolarHBondContact O-N 3.44Å; W23-I26 HydrophobicContact CE3-CG1 4.2Å; W23-I26 PolarHBondContact O-N 3.18Å; W23-P27 VanDerWaalsContact O-CD 3.28Å; W23-P27 WeakPolarHBondContact O-CD 3.42Å; W23-E50 HydrophobicContact CH2-CG 4.1Å; W23-E50 HydrophobicContact CZ3-CG 3.85Å; W23-S51 PolarHBondContact O-OG 3.06Å; W23-S51 VanDerWaalsContact O-OG 3.08Å; W23-Q54 HydrophobicContact CD2-CB 3.7Å; W23-Q54 HydrophobicContact CD2-CG 4.13Å; W23-Q54 VanDerWaalsContact CE2-CB 3.48Å; W23-Q54 HydrophobicContact CE3-CB 4.34Å; W23-Q54 HydrophobicContact CE3-CG 4.43Å; W23-Q54 HydrophobicContact CG-CB 3.91Å; W23-Q54 HydrophobicContact CH2-CG 3.96Å; W23-Q54 HydrophobicContact CZ2-CB 3.98Å; W23-Q54 HydrophobicContact CZ2-CG 3.62Å; W23-Q54 HydrophobicContact CZ3-CG 4.35Å
24D85.7Confident83.9Confident122 Ų12254.1 Ų54.165%0.65226%0.264SS*.G310 helixtrans-63-28.8179.2-56.2-41.6000113.3Q22Q22-D24 PolarHBondContact O-N 3.1Å
25K85.9Confident82.7Confident94 Ų9457.6 Ų57.641%0.40929%0.294SS..G310 helixtrans-85.4-20.6-178.6-64.3-178.1-175169.60113.1Q22 W23 E28 L29Q22-K25 HydrophobicContact CB-CD 4.4Å; Q22-K25 PolarHBondContact O-N 3.36Å; W23-K25 PolarHBondContact O-N 3.44Å; K25-E28 PolarHBondContact O-N 2.94Å; K25-L29 HydrophobicContact CB-CD1 4.49Å; K25-L29 WeakPolarHBondContact O-CG 3.42Å; K25-L29 PolarHBondContact O-N 3.12Å; K25-L29 VanDerWaalsContact O-N 3.08Å
26I87.2Confident81.1Confident1 Ų163.9 Ų63.91%0.00532%0.32CS..Hα-helixtrans-60.7-44.9-174.6-61.2-64.2000111.9C17 R18 W23 E28 L29 V30 L47C17-I26 HydrophobicContact CB-CD1 3.6Å; R18-I26 HydrophobicContact CG-CD1 4.05Å; W23-I26 HydrophobicContact CE3-CG1 4.2Å; W23-I26 PolarHBondContact O-N 3.18Å; I26-E28 VanDerWaalsContact C-N 3.26Å; I26-E28 PolarHBondContact O-N 2.8Å; I26-L29 PolarHBondContact O-N 3.26Å; I26-V30 HydrophobicContact CG2-CG2 4.1Å; I26-V30 VanDerWaalsContact O-CG2 3.29Å; I26-V30 WeakPolarHBondContact O-CG2 3.39Å; I26-V30 PolarHBondContact O-N 2.99Å; I26-L47 HydrophobicContact CG2-CB 3.97Å
27P87.4Confident79.9Confident34 Ų3464.9 Ų64.922%0.22133%0.331CS..Hα-helixtrans-59.8-33.6177.1-25.835.2000114W23 R31 L48W23-P27 VanDerWaalsContact O-CD 3.28Å; W23-P27 WeakPolarHBondContact O-CD 3.42Å; P27-R31 WeakPolarHBondContact O-CG 3.44Å; P27-R31 PolarHBondContact O-N 3.26Å; P27-L48 HydrophobicContact CB-CD2 4.04Å; P27-L48 HydrophobicContact CG-CD2 4.26Å
28E85.8Confident78.7Confident114 Ų11470.6 Ų70.653%0.53336%0.36SS..Hα-helixtrans-74.3-39.3177.8-63.2-174.1166.300112.2K25 I26 R31 Q32K25-E28 PolarHBondContact O-N 2.94Å; I26-E28 VanDerWaalsContact C-N 3.26Å; I26-E28 PolarHBondContact O-N 2.8Å; E28-R31 PolarHBondContact O-N 3.37Å; E28-Q32 WeakPolarHBondContact O-CG 3.43Å; E28-Q32 PolarHBondContact O-NE2 3.02Å
29L84.6Confident77.5Confident21 Ų2172 Ų7211%0.1137%0.372CS..Hα-helixtrans-68.6-36.6176.5-65.9173.6000111.7L10 E13 I14 C17 K25 I26 R31 Q32 L33L10-L29 HydrophobicContact CD1-CB 4.34Å; L10-L29 HydrophobicContact CD1-CD2 3.84Å; E13-L29 HydrophobicContact CG-CD1 4.23Å; E13-L29 HydrophobicContact CG-CD2 4.26Å; I14-L29 HydrophobicContact CD1-CB 4.42Å; I14-L29 HydrophobicContact CG1-CB 3.86Å; I14-L29 HydrophobicContact CG1-CD1 4.11Å; C17-L29 HydrophobicContact CB-CD1 4.26Å; K25-L29 HydrophobicContact CB-CD1 4.49Å; K25-L29 WeakPolarHBondContact O-CG 3.42Å; K25-L29 PolarHBondContact O-N 3.12Å; K25-L29 VanDerWaalsContact O-N 3.08Å; I26-L29 PolarHBondContact O-N 3.26Å; L29-R31 VanDerWaalsContact C-N 3.33Å; L29-R31 PolarHBondContact O-N 2.82Å; L29-Q32 WeakPolarHBondContact O-CB 3.49Å; L29-Q32 PolarHBondContact O-N 2.84Å; L29-Q32 VanDerWaalsContact O-N 3.09Å; L29-L33 PolarHBondContact O-N 3.23Å
30V84.1Confident76.6Confident20 Ų2072 Ų7212%0.12137%0.369CS..Hα-helixtrans-63.5-38.3175.7170.10000111.4I26 Q32 L33 L47 L48I26-V30 HydrophobicContact CG2-CG2 4.1Å; I26-V30 VanDerWaalsContact O-CG2 3.29Å; I26-V30 WeakPolarHBondContact O-CG2 3.39Å; I26-V30 PolarHBondContact O-N 2.99Å; V30-Q32 PolarHBondContact O-N 3.32Å; V30-L33 HydrophobicContact CB-CD1 4.4Å; V30-L33 HydrophobicContact CG1-CD1 4.3Å; V30-L33 HydrophobicContact CG2-CD1 4.38Å; V30-L33 WeakPolarHBondContact O-CB 3.49Å; V30-L33 PolarHBondContact O-N 3.36Å; V30-L33 VanDerWaalsContact O-N 3.11Å; V30-L47 HydrophobicContact CG2-CB 3.7Å; V30-L47 HydrophobicContact CG2-CD1 3.88Å; V30-L47 HydrophobicContact CG2-CG 4.47Å; V30-L48 HydrophobicContact CG1-CD1 4.14Å; V30-L48 HydrophobicContact CG1-CG 4.13Å
31R82.5Confident76.2Confident189 Ų18973.6 Ų73.671%0.71338%0.38SS*.Hα-helixtrans-63.7-21.2174.7-69.3179.1-153.6125.23.4113.5P27 E28 L29P27-R31 WeakPolarHBondContact O-CG 3.44Å; P27-R31 PolarHBondContact O-N 3.26Å; E28-R31 PolarHBondContact O-N 3.37Å; L29-R31 VanDerWaalsContact C-N 3.33Å; L29-R31 PolarHBondContact O-N 2.82Å
32Q81.1Confident76.1Confident125 Ų12572.3 Ų72.358%0.58437%0.366SS*.THydrogen-bonded Turntrans-88.5-7.1179-62.6172.73300112.6L10 E28 L29 V30L10-Q32 HydrophobicContact CD1-CB 4.23Å; L10-Q32 HydrophobicContact CD2-CB 3.98Å; L10-Q32 WeakPolarHBondContact CD2-O 3.4Å; E28-Q32 WeakPolarHBondContact O-CG 3.43Å; E28-Q32 PolarHBondContact O-NE2 3.02Å; L29-Q32 WeakPolarHBondContact O-CB 3.49Å; L29-Q32 PolarHBondContact O-N 2.84Å; L29-Q32 VanDerWaalsContact O-N 3.09Å; V30-Q32 PolarHBondContact O-N 3.32Å
33L78.1Confident76Confident20 Ų2071.3 Ų71.311%0.10536%0.362CS..SBendtrans-65.3135.5174.3-76.5160.3000110L10 I14 L29 V30 A35 L47L10-L33 HydrophobicContact CD2-CD2 4.06Å; L10-L33 HydrophobicContact CD2-CG 4.13Å; I14-L33 HydrophobicContact CD1-CD1 4.32Å; I14-L33 HydrophobicContact CD1-CD2 4.29Å; I14-L33 HydrophobicContact CD1-CG 4.36Å; L29-L33 PolarHBondContact O-N 3.23Å; V30-L33 HydrophobicContact CB-CD1 4.4Å; V30-L33 HydrophobicContact CG1-CD1 4.3Å; V30-L33 HydrophobicContact CG2-CD1 4.38Å; V30-L33 WeakPolarHBondContact O-CB 3.49Å; V30-L33 PolarHBondContact O-N 3.36Å; V30-L33 VanDerWaalsContact O-N 3.11Å; L33-A35 PolarHBondContact O-N 3.28Å; L33-A35 VanDerWaalsContact O-N 3.12Å; L33-L47 HydrophobicContact CD1-CD1 4.42Å
34P66.6Low75.8Confident69 Ų6969.9 Ų69.945%0.44836%0.358SS..  trans-70.6113.6-178.223.4-27.2000110.5K36 N40P34-K36 PolarHBondContact O-N 3.28Å; P34-N40 PolarHBondContact O-ND2 2.92Å
35A58.9Low75.9Confident81 Ų8166.7 Ų66.767%0.66934%0.339SS*.THydrogen-bonded Turntrans-64.216.3177.900000115.3L33L33-A35 PolarHBondContact O-N 3.28Å; L33-A35 VanDerWaalsContact O-N 3.12Å
36K53.3Low76Confident198 Ų19862.2 Ų62.286%0.86132%0.319SS*.THydrogen-bonded Turntrans-96.3-8.2-177.1-72-172.9177.4-177.10113.7P34P34-K36 PolarHBondContact O-N 3.28Å
37L59.7Low76.1Confident100 Ų10062.3 Ų62.352%0.52432%0.32SS..SBendtrans-120.5126.4171.9-89.193.2000109.2S39 N40L37-S39 PolarHBondContact O-N 3.35Å; L37-N40 HydrophobicContact CB-CB 4.47Å; L37-N40 WeakPolarHBondContact O-CB 3.22Å; L37-N40 PolarHBondContact O-N 3.39Å
38I59.3Low76.2Confident120 Ų12062.5 Ų62.562%0.61532%0.319SS*.Hα-helixtrans-57.5-31.3177.1-58.6162000111.1N40 D41 D42I38-N40 PolarHBondContact O-N 3.36Å; I38-D41 PolarHBondContact O-N 2.82Å; I38-D42 PolarHBondContact O-N 2.92Å
39S62.8Low76.4Confident40 Ų4057 Ų5728%0.2829%0.293SS..Hα-helixtrans-63.9-24.317461.50000114.1L37 L43L37-S39 PolarHBondContact O-N 3.35Å; S39-L43 WeakPolarHBondContact O-CB 3.45Å; S39-L43 PolarHBondContact O-N 3.34Å
40N68.3Low76.8Confident22 Ų2256.1 Ų56.112%0.11829%0.288CS..Hα-helixtrans-82-29.2179.1-66.2-7.1000112P34 L37 I38 G44P34-N40 PolarHBondContact O-ND2 2.92Å; L37-N40 HydrophobicContact CB-CB 4.47Å; L37-N40 WeakPolarHBondContact O-CB 3.22Å; L37-N40 PolarHBondContact O-N 3.39Å; I38-N40 PolarHBondContact O-N 3.36Å; N40-G44 PolarHBondContact O-N 3.34Å
41D73.3Confident77.1Confident79 Ų7955.5 Ų55.542%0.42229%0.285SS..Hα-helixtrans-67.7-45.4174.4-66.9-19.5000109.7I38 L43 G44 E45I38-D41 PolarHBondContact O-N 2.82Å; D41-L43 VanDerWaalsContact C-N 3.32Å; D41-L43 PolarHBondContact O-N 3.33Å; D41-G44 WeakPolarHBondContact O-CA 3.29Å; D41-G44 PolarHBondContact O-N 3.08Å; D41-G44 VanDerWaalsContact O-N 3.13Å; D41-E45 WeakPolarHBondContact O-CG 3.04Å; D41-E45 PolarHBondContact O-N 2.94Å
42D80.8Confident77.5Confident0 Ų049.8 Ų49.80%027%0.265CS..Hα-helixtrans-68.3-30.7177.5-64.2-19.5000112.4I38 E45 L46 R88 N90 L91I38-D42 PolarHBondContact O-N 2.92Å; D42-E45 PolarHBondContact O-N 3.38Å; D42-L46 PolarHBondContact O-N 2.86Å; D42-L46 VanDerWaalsContact O-N 3.15Å; D42-R88 WeakPolarHBondContact OD1-CD 3.49Å; D42-R88 IonicContact OD1-CZ 3.9Å; D42-R88 IonicContact OD1-NE 2.85Å; D42-R88 IonicContact OD1-NH1 3.72Å; D42-R88 PolarHBondContact OD1-NH1 2.93Å; D42-R88 WeakPolarHBondContact OD2-CB 3.49Å; D42-N90 WeakPolarHBondContact OD2-CB 3.39Å; D42-N90 PolarHBondContact OD2-ND2 3.42Å; D42-L91 HydrophobicContact CB-CD2 4.13Å; D42-L91 HydrophobicContact CB-CG 4.04Å
43L82.8Confident77.9Confident15 Ų1543.9 Ų43.98%0.07924%0.237CC..Hα-helixtrans-68.4-38171.4-17962.4000111.1S39 D41 L46 L47 L91 Y95S39-L43 WeakPolarHBondContact O-CB 3.45Å; S39-L43 PolarHBondContact O-N 3.34Å; D41-L43 VanDerWaalsContact C-N 3.32Å; D41-L43 PolarHBondContact O-N 3.33Å; L43-L46 HydrophobicContact CD1-CD2 4.45Å; L43-L46 PolarHBondContact O-N 2.84Å; L43-L47 HydrophobicContact CD1-CD1 4.34Å; L43-L47 HydrophobicContact CD1-CG 4.4Å; L43-L47 HydrophobicContact CG-CD1 4.04Å; L43-L47 VanDerWaalsContact O-CG 3.23Å; L43-L47 WeakPolarHBondContact O-CG 3.27Å; L43-L47 PolarHBondContact O-N 3.47Å; L43-L91 HydrophobicContact CB-CD2 3.95Å; L43-L91 HydrophobicContact CD1-CD2 4.45Å; L43-Y95 HydrophobicContact CD1-CD1 3.99Å; L43-Y95 HydrophobicContact CD1-CD2 4.06Å; L43-Y95 HydrophobicContact CD1-CE1 4.04Å; L43-Y95 HydrophobicContact CD1-CE2 4.09Å; L43-Y95 HydrophobicContact CD1-CG 4.02Å
44G83.3Confident78.5Confident4 Ų444.2 Ų44.24%0.04124%0.238CC..Hα-helixtrans-61.2-43.6173.200000112.5N40 D41 L47 L48N40-G44 PolarHBondContact O-N 3.34Å; D41-G44 WeakPolarHBondContact O-CA 3.29Å; D41-G44 PolarHBondContact O-N 3.08Å; D41-G44 VanDerWaalsContact O-N 3.13Å; G44-L47 PolarHBondContact O-N 3.15Å; G44-L48 WeakPolarHBondContact O-CB 3.43Å; G44-L48 VanDerWaalsContact O-CG 3.26Å; G44-L48 WeakPolarHBondContact O-CG 3.45Å; G44-L48 PolarHBondContact O-N 2.67Å
45E87.4Confident79.5Confident55 Ų5542.7 Ų42.726%0.25723%0.228SC..Hα-helixtrans-60.8-44.6175.9-66.3-66.3142.400112D41 D42 G49 H81 A85D41-E45 WeakPolarHBondContact O-CG 3.04Å; D41-E45 PolarHBondContact O-N 2.94Å; D42-E45 PolarHBondContact O-N 3.38Å; E45-G49 PolarHBondContact O-N 3.16Å; E45-H81 IonicContact OE2-CE1 3.87Å; E45-H81 IonicContact OE2-CG 2.95Å; E45-H81 IonicContact OE2-ND1 3.36Å; E45-H81 PolarHBondContact OE2-ND1 2.98Å; E45-A85 HydrophobicContact CB-CB 4.43Å
46L89.1Confident81Confident0 Ų039.4 Ų39.40%020%0.198CC..Hα-helixtrans-58-51.1174.6172.960.3000112.1D42 L43 L48 G49 E50 L82 A85 L91 Y95 E98 A99 L102D42-L46 PolarHBondContact O-N 2.86Å; D42-L46 VanDerWaalsContact O-N 3.15Å; L43-L46 HydrophobicContact CD1-CD2 4.45Å; L43-L46 PolarHBondContact O-N 2.84Å; L46-L48 PolarHBondContact O-N 3.32Å; L46-G49 PolarHBondContact O-N 3.46Å; L46-E50 PolarHBondContact O-N 2.99Å; L46-L82 HydrophobicContact CD1-CD2 3.77Å; L46-A85 HydrophobicContact CB-CB 4.4Å; L46-L91 HydrophobicContact CD2-CD1 4.42Å; L46-Y95 HydrophobicContact CD2-CD1 4.13Å; L46-Y95 HydrophobicContact CD2-CG 4.33Å; L46-E98 HydrophobicContact CD2-CB 4.37Å; L46-A99 HydrophobicContact CD1-CB 3.77Å; L46-L102 HydrophobicContact CD1-CD1 3.81Å
47L89.6Confident82.6Confident2 Ų231 Ų311%0.0116%0.163CC..Hα-helixtrans-66-37.9-176.7-68.7171000112.4I14 R18 I26 V30 L33 L43 G44 S51I14-L47 HydrophobicContact CD1-CD1 4.15Å; I14-L47 HydrophobicContact CG2-CD1 3.73Å; I14-L47 HydrophobicContact CG2-CD2 3.76Å; I14-L47 HydrophobicContact CG2-CG 4.41Å; R18-L47 HydrophobicContact CG-CD2 4.5Å; I26-L47 HydrophobicContact CG2-CB 3.97Å; V30-L47 HydrophobicContact CG2-CB 3.7Å; V30-L47 HydrophobicContact CG2-CD1 3.88Å; V30-L47 HydrophobicContact CG2-CG 4.47Å; L33-L47 HydrophobicContact CD1-CD1 4.42Å; L43-L47 HydrophobicContact CD1-CD1 4.34Å; L43-L47 HydrophobicContact CD1-CG 4.4Å; L43-L47 HydrophobicContact CG-CD1 4.04Å; L43-L47 VanDerWaalsContact O-CG 3.23Å; L43-L47 WeakPolarHBondContact O-CG 3.27Å; L43-L47 PolarHBondContact O-N 3.47Å; G44-L47 PolarHBondContact O-N 3.15Å; L47-S51 VanDerWaalsContact O-CB 3.23Å; L47-S51 WeakPolarHBondContact O-CB 3.31Å; L47-S51 PolarHBondContact O-N 2.92Å
48L89.1Confident83.8Confident38 Ų3832.7 Ų32.720%0.19917%0.166CC..Hα-helixtrans-67.7-40.2174.1-72.5171.5000111.7P27 V30 G44 L46 K52P27-L48 HydrophobicContact CB-CD2 4.04Å; P27-L48 HydrophobicContact CG-CD2 4.26Å; V30-L48 HydrophobicContact CG1-CD1 4.14Å; V30-L48 HydrophobicContact CG1-CG 4.13Å; G44-L48 WeakPolarHBondContact O-CB 3.43Å; G44-L48 VanDerWaalsContact O-CG 3.26Å; G44-L48 WeakPolarHBondContact O-CG 3.45Å; G44-L48 PolarHBondContact O-N 2.67Å; L46-L48 PolarHBondContact O-N 3.32Å; L48-K52 WeakPolarHBondContact O-CB 3.2Å; L48-K52 WeakPolarHBondContact O-CG 3.49Å; L48-K52 PolarHBondContact O-N 2.97Å
49G89.6Confident85.1Confident0 Ų033.8 Ų33.80%017%0.168CC..Hα-helixtrans-59.5-51.5173.600000111.9E45 L46 K52 L53 V78E45-G49 PolarHBondContact O-N 3.16Å; L46-G49 PolarHBondContact O-N 3.46Å; G49-K52 PolarHBondContact O-N 3.37Å; G49-L53 WeakPolarHBondContact O-CB 3.33Å; G49-L53 PolarHBondContact O-N 3.48Å; G49-V78 WeakPolarHBondContact O-CG1 3.43Å
50E92.4Very high86.2Confident2 Ų234.1 Ų34.11%0.00917%0.167CC..Hα-helixtrans-59.9-48.1177.3-171.2-177.8-138.100112.3R18 W23 L46 K52 L53 Q54 L102R18-E50 IonicContact CZ-OE1 2.75Å; R18-E50 IonicContact CZ-OE2 2.71Å; R18-E50 IonicContact NE-OE1 2.66Å; R18-E50 IonicContact NE-OE2 2.64Å; R18-E50 PolarHBondContact NE-OE2 3.21Å; R18-E50 IonicContact NH2-OE1 3.62Å; R18-E50 PolarHBondContact NH2-OE1 3.38Å; R18-E50 IonicContact NH2-OE2 3.04Å; R18-E50 PolarHBondContact NH2-OE2 3.35Å; W23-E50 HydrophobicContact CH2-CG 4.1Å; W23-E50 HydrophobicContact CZ3-CG 3.85Å; L46-E50 PolarHBondContact O-N 2.99Å; E50-K52 PolarHBondContact O-N 2.62Å; E50-L53 PolarHBondContact O-N 2.87Å; E50-Q54 HydrophobicContact CG-CG 4.24Å; E50-Q54 WeakPolarHBondContact O-CB 3.29Å; E50-Q54 VanDerWaalsContact O-CG 3.3Å; E50-Q54 WeakPolarHBondContact O-CG 3.3Å; E50-Q54 PolarHBondContact O-N 3Å; E50-L102 HydrophobicContact CB-CD1 3.66Å; E50-L102 HydrophobicContact CG-CD1 3.83Å; E50-L102 HydrophobicContact CG-CD2 4.04Å
51S91.7Very high86.9Confident6 Ų637.1 Ų37.14%0.04219%0.188CC..Hα-helixtrans-57.6-47.3179.5167.80000112W23 L47 Q54 T55W23-S51 PolarHBondContact O-OG 3.06Å; W23-S51 VanDerWaalsContact O-OG 3.08Å; L47-S51 VanDerWaalsContact O-CB 3.23Å; L47-S51 WeakPolarHBondContact O-CB 3.31Å; L47-S51 PolarHBondContact O-N 2.92Å; S51-Q54 PolarHBondContact O-N 3.33Å; S51-T55 WeakPolarHBondContact O-CB 3.43Å; S51-T55 PolarHBondContact O-N 3.49Å; S51-T55 PolarHBondContact O-OG1 3.46Å
52K90.6Very high87.4Confident70 Ų7034.5 Ų34.530%0.30417%0.174SC..Hα-helixtrans-64.4-40.2177.3-76.6-179.5177.1-173.40112L48 G49 E50 Y56 E77 V78 H81L48-K52 WeakPolarHBondContact O-CB 3.2Å; L48-K52 WeakPolarHBondContact O-CG 3.49Å; L48-K52 PolarHBondContact O-N 2.97Å; G49-K52 PolarHBondContact O-N 3.37Å; E50-K52 PolarHBondContact O-N 2.62Å; K52-Y56 VanDerWaalsContact O-CB 3.3Å; K52-Y56 WeakPolarHBondContact O-CB 3.49Å; K52-Y56 PolarHBondContact O-N 2.95Å; K52-E77 IonicContact NZ-OE2 3.96Å; K52-E77 PolarHBondContact NZ-OE2 2.98Å; K52-V78 HydrophobicContact CB-CG2 3.61Å; K52-H81 PolarHBondContact NZ-NE2 3.25Å
53L89.8Confident87.3Confident0 Ų042.2 Ų42.20%021%0.207CC..Hα-helixtrans-63.1-48.2178.1-177.558000111.8G49 E50 Y56 L57 L75 V78 L102 K105 I106 I109G49-L53 WeakPolarHBondContact O-CB 3.33Å; G49-L53 PolarHBondContact O-N 3.48Å; E50-L53 PolarHBondContact O-N 2.87Å; L53-Y56 WeakPolarHBondContact O-CB 3.25Å; L53-Y56 PolarHBondContact O-N 3.26Å; L53-L57 HydrophobicContact CG-CD1 4.35Å; L53-L57 WeakPolarHBondContact O-CG 3.2Å; L53-L57 PolarHBondContact O-N 3.3Å; L53-L75 HydrophobicContact CD1-CD2 3.97Å; L53-V78 HydrophobicContact CB-CG1 4.03Å; L53-V78 HydrophobicContact CB-CG2 4.23Å; L53-L102 HydrophobicContact CD2-CD2 4.22Å; L53-K105 HydrophobicContact CD2-CD 4.2Å; L53-I106 HydrophobicContact CD1-CG1 3.9Å; L53-I106 HydrophobicContact CD2-CD1 4.33Å; L53-I106 HydrophobicContact CD2-CG1 3.86Å; L53-I109 HydrophobicContact CD1-CD1 3.97Å
54Q89.3Confident86.9Confident27 Ų2748.2 Ų48.213%0.12624%0.235CC..Hα-helixtrans-69.4-37.7-177.7-65.4-70.93.100111.7W23 E50 S51 L57 K58W23-Q54 HydrophobicContact CD2-CB 3.7Å; W23-Q54 HydrophobicContact CD2-CG 4.13Å; W23-Q54 VanDerWaalsContact CE2-CB 3.48Å; W23-Q54 HydrophobicContact CE3-CB 4.34Å; W23-Q54 HydrophobicContact CE3-CG 4.43Å; W23-Q54 HydrophobicContact CG-CB 3.91Å; W23-Q54 HydrophobicContact CH2-CG 3.96Å; W23-Q54 HydrophobicContact CZ2-CB 3.98Å; W23-Q54 HydrophobicContact CZ2-CG 3.62Å; W23-Q54 HydrophobicContact CZ3-CG 4.35Å; E50-Q54 HydrophobicContact CG-CG 4.24Å; E50-Q54 WeakPolarHBondContact O-CB 3.29Å; E50-Q54 VanDerWaalsContact O-CG 3.3Å; E50-Q54 WeakPolarHBondContact O-CG 3.3Å; E50-Q54 PolarHBondContact O-N 3Å; S51-Q54 PolarHBondContact O-N 3.33Å; Q54-L57 PolarHBondContact O-N 2.87Å; Q54-K58 WeakPolarHBondContact O-CB 3.1Å; Q54-K58 PolarHBondContact O-N 3.16Å
55T88.7Confident86.2Confident37 Ų3751.9 Ų51.923%0.22727%0.273CS..Hα-helixtrans-61.7-45.3172.6-53.10000110.9S51 L57 K58 E59S51-T55 WeakPolarHBondContact O-CB 3.43Å; S51-T55 PolarHBondContact O-N 3.49Å; S51-T55 PolarHBondContact O-OG1 3.46Å; T55-L57 VanDerWaalsContact C-N 3.35Å; T55-L57 PolarHBondContact O-N 2.87Å; T55-K58 WeakPolarHBondContact O-CB 3.19Å; T55-K58 PolarHBondContact O-N 2.84Å; T55-E59 WeakPolarHBondContact O-CG 3.45Å; T55-E59 PolarHBondContact O-N 2.65Å
56Y89.1Confident85.6Confident12 Ų1251.5 Ų51.55%0.04728%0.276CS..Hα-helixtrans-59.7-42.9176.1170.4-96.7000112.5K52 L53 K58 E59 N60 R72 T74 L75K52-Y56 VanDerWaalsContact O-CB 3.3Å; K52-Y56 WeakPolarHBondContact O-CB 3.49Å; K52-Y56 PolarHBondContact O-N 2.95Å; L53-Y56 WeakPolarHBondContact O-CB 3.25Å; L53-Y56 PolarHBondContact O-N 3.26Å; Y56-K58 VanDerWaalsContact C-N 3.34Å; Y56-E59 PolarHBondContact O-N 2.95Å; Y56-N60 HydrophobicContact CE2-CB 4.3Å; Y56-N60 WeakPolarHBondContact O-CB 3.32Å; Y56-N60 PolarHBondContact O-N 3.21Å; Y56-N60 PolarHBondContact O-ND2 3.49Å; Y56-R72 WeakPolarHBondContact OH-CD 3.24Å; Y56-R72 PolarHBondContact OH-NE 2.93Å; Y56-R72 PolarHBondContact OH-NH1 3.27Å; Y56-T74 WeakPolarHBondContact CD2-OG1 3.47Å; Y56-L75 HydrophobicContact CD1-CD2 3.81Å; Y56-L75 HydrophobicContact CD1-CG 4.49Å; Y56-L75 HydrophobicContact CE1-CD1 4.2Å; Y56-L75 HydrophobicContact CE1-CD2 3.85Å; Y56-L75 HydrophobicContact CE1-CG 4.19Å; Y56-L75 HydrophobicContact CG-CD2 4.43Å
57L87.1Confident84.8Confident22 Ų2255.8 Ų55.812%0.11531%0.306CS..Hα-helixtrans-66.5-34.3177.6-72.9174.3000112.7L53 Q54 T55 N60 I62 K105 I109 F226L53-L57 HydrophobicContact CG-CD1 4.35Å; L53-L57 WeakPolarHBondContact O-CG 3.2Å; L53-L57 PolarHBondContact O-N 3.3Å; Q54-L57 PolarHBondContact O-N 2.87Å; T55-L57 VanDerWaalsContact C-N 3.35Å; T55-L57 PolarHBondContact O-N 2.87Å; L57-N60 CarbonylContact O-C 3.4Å; L57-N60 VanDerWaalsContact O-C 3.26Å; L57-I62 HydrophobicContact CD2-CD1 3.7Å; L57-I62 HydrophobicContact CD2-CG1 4.11Å; L57-K105 HydrophobicContact CD1-CD 4.4Å; L57-I109 HydrophobicContact CD1-CD1 4.41Å; L57-I109 HydrophobicContact CD2-CD1 3.85Å; L57-I109 HydrophobicContact CG-CD1 4.47Å; L57-F226 HydrophobicContact CD1-CE2 4.3Å
58K85.6Confident84.2Confident136 Ų13658.8 Ų58.859%0.59133%0.326SS*.Hα-helixtrans-67.3-42174.8-170.7177.1-178.7179.20111.9Q54 T55 Y56Q54-K58 WeakPolarHBondContact O-CB 3.1Å; Q54-K58 PolarHBondContact O-N 3.16Å; T55-K58 WeakPolarHBondContact O-CB 3.19Å; T55-K58 PolarHBondContact O-N 2.84Å; Y56-K58 VanDerWaalsContact C-N 3.34Å
59E86.6Confident83.4Confident142 Ų14261 Ų6166%0.66433%0.331SS*.Hα-helixtrans-74.3-27.4176.7-68.6175.8175.900113T55 Y56T55-E59 WeakPolarHBondContact O-CG 3.45Å; T55-E59 PolarHBondContact O-N 2.65Å; Y56-E59 PolarHBondContact O-N 2.95Å
60N85.3Confident82.2Confident47 Ų4762.6 Ų62.625%0.25135%0.348SS..SBendtrans-127.773.6-177.3-61.7-100.3000111.4Y56 L57 I62 R72Y56-N60 HydrophobicContact CE2-CB 4.3Å; Y56-N60 WeakPolarHBondContact O-CB 3.32Å; Y56-N60 PolarHBondContact O-N 3.21Å; Y56-N60 PolarHBondContact O-ND2 3.49Å; L57-N60 CarbonylContact O-C 3.4Å; L57-N60 VanDerWaalsContact O-C 3.26Å; N60-I62 PolarHBondContact O-N 3.27Å; N60-R72 PolarHBondContact OD1-NH1 2.96Å
61P83.6Confident81.1Confident86 Ų8668 Ų6856%0.55838%0.381SS*.PPolyproline II helixtrans-56.7136.6-179.4-25.234.1000112.7
62I84.6Confident80.6Confident24 Ų2471.7 Ų71.712%0.12339%0.394CS..PPolyproline II helixtrans-81.2128.3175.2-58.8173.8000108.1L57 N60 I109 Y225 F226L57-I62 HydrophobicContact CD2-CD1 3.7Å; L57-I62 HydrophobicContact CD2-CG1 4.11Å; N60-I62 PolarHBondContact O-N 3.27Å; I62-I109 HydrophobicContact CD1-CG1 4.18Å; I62-Y225 HydrophobicContact CB-CD1 3.81Å; I62-Y225 HydrophobicContact CB-CD2 4.37Å; I62-Y225 HydrophobicContact CB-CE1 4.28Å; I62-Y225 HydrophobicContact CB-CG 3.86Å; I62-Y225 HydrophobicContact CD1-CD1 4.26Å; I62-Y225 HydrophobicContact CG2-CD1 3.72Å; I62-Y225 HydrophobicContact CG2-CD2 4.27Å; I62-Y225 HydrophobicContact CG2-CE1 3.65Å; I62-Y225 HydrophobicContact CG2-CE2 4.22Å; I62-Y225 HydrophobicContact CG2-CG 4.04Å; I62-Y225 WeakPolarHBondContact O-CD2 3.46Å; I62-F226 HydrophobicContact CD1-CE2 4.13Å; I62-F226 HydrophobicContact CD1-CZ 3.83Å
63K79Confident80.1Confident161 Ų16172.1 Ų72.170%0.741%0.41SS*.PPolyproline II helixtrans-101.4144.6173.7-65.6-173.4179.1-175.50109.2G65 S66K63-G65 PolarHBondContact O-N 3.37Å; K63-S66 WeakPolarHBondContact O-CB 3.45Å; K63-S66 PolarHBondContact O-N 3.29Å; K63-S66 VanDerWaalsContact O-N 3.12Å; K63-S66 PolarHBondContact O-OG 2.95Å
64Q74.1Confident79.9Confident142 Ų14275.2 Ų75.266%0.66443%0.429SS*.THydrogen-bonded Turntrans-56.4127.4177.3-167.9175.933.100110.8Y225Q64-Y225 HydrophobicContact CB-CE2 4.38Å
65G67.1Low79.7Confident81 Ų8173.9 Ų73.984%0.83542%0.423SS*.THydrogen-bonded Turntrans80.69-18000000115.8K63K63-G65 PolarHBondContact O-N 3.37Å
66S75.2Confident79.7Confident47 Ų4775.9 Ų75.933%0.32944%0.435SS..PPolyproline II helixtrans-69.3146.8172.863.30000112.2K63K63-S66 WeakPolarHBondContact O-CB 3.45Å; K63-S66 PolarHBondContact O-N 3.29Å; K63-S66 VanDerWaalsContact O-N 3.12Å; K63-S66 PolarHBondContact O-OG 2.95Å
67S73.1Confident79.7Confident90 Ų9079.8 Ų79.863%0.62945%0.454SS*.PPolyproline II helixtrans-62.2153.4172.653.30000112.2R69S67-R69 PolarHBondContact O-N 3.25Å
68P77.3Confident79.8Confident65 Ų6578.8 Ų78.842%0.42245%0.448SS..PPolyproline II helixtrans-51.3139.9173.4-2735000111.6G70P68-G70 PolarHBondContact O-N 3.24Å
69R71.7Confident80Confident85 Ų8575.1 Ų75.132%0.32143%0.431SS..  trans-78.2-0.2-169.9-69.8-64-167174.64.1114.3S67 I109S67-R69 PolarHBondContact O-N 3.25Å; R69-I109 HydrophobicContact CB-CG2 4.06Å; R69-I109 HydrophobicContact CG-CG2 4.38Å; R69-I109 PolarHBondContact N-O 3.19Å
70G65.1Low80.2Confident33 Ų3376 Ų7634%0.3443%0.432SS..  trans61.9178.7-178.900000113.2P68 R72P68-G70 PolarHBondContact O-N 3.24Å; G70-R72 PolarHBondContact O-N 3.44Å
71T69Low80.4Confident116 Ų11675.2 Ų75.271%0.71243%0.427SS*.  trans-75.7103.5178.444.10000110.8
72R80.5Confident80.6Confident82 Ų8271.1 Ų71.131%0.30940%0.401SS..  trans-100.2150.2174.7-65.3-170.3-178.2-171-15.3110.9Y56 N60 G70 T74 L75 V76Y56-R72 WeakPolarHBondContact OH-CD 3.24Å; Y56-R72 PolarHBondContact OH-NE 2.93Å; Y56-R72 PolarHBondContact OH-NH1 3.27Å; N60-R72 PolarHBondContact OD1-NH1 2.96Å; G70-R72 PolarHBondContact O-N 3.44Å; R72-T74 VanDerWaalsContact C-N 3.26Å; R72-T74 PolarHBondContact O-N 2.91Å; R72-L75 HydrophobicContact CB-CD1 4.32Å; R72-L75 HydrophobicContact CB-CG 4.36Å; R72-L75 PolarHBondContact O-N 3.33Å; R72-V76 WeakPolarHBondContact O-CG2 3.49Å; R72-V76 PolarHBondContact O-N 3.16Å
73A81.3Confident80.9Confident79 Ų7972.4 Ų72.465%0.65341%0.41SS*.Hα-helixtrans-53.5-41.3-177.600000113.2V76 E77A73-V76 PolarHBondContact O-N 3.35Å; A73-E77 PolarHBondContact O-N 3.45Å; A73-E77 VanDerWaalsContact O-N 3.08Å
74T84.1Confident81.2Confident65 Ų6565.8 Ų65.840%0.39939%0.385SS..Hα-helixtrans-64.6-42.2176510000112.7Y56 R72 E77 V78Y56-T74 WeakPolarHBondContact CD2-OG1 3.47Å; R72-T74 VanDerWaalsContact C-N 3.26Å; R72-T74 PolarHBondContact O-N 2.91Å; T74-E77 PolarHBondContact O-N 2.8Å; T74-V78 WeakPolarHBondContact O-CG2 3.48Å; T74-V78 PolarHBondContact O-N 3.05Å
75L86.2Confident81.7Confident0 Ų059 Ų590%035%0.354CS..Hα-helixtrans-68.2-35.5177.9-64.8177.4000111.9L53 Y56 R72 E77 V78 R79 I109 E110L53-L75 HydrophobicContact CD1-CD2 3.97Å; Y56-L75 HydrophobicContact CD1-CD2 3.81Å; Y56-L75 HydrophobicContact CD1-CG 4.49Å; Y56-L75 HydrophobicContact CE1-CD1 4.2Å; Y56-L75 HydrophobicContact CE1-CD2 3.85Å; Y56-L75 HydrophobicContact CE1-CG 4.19Å; Y56-L75 HydrophobicContact CG-CD2 4.43Å; R72-L75 HydrophobicContact CB-CD1 4.32Å; R72-L75 HydrophobicContact CB-CG 4.36Å; R72-L75 PolarHBondContact O-N 3.33Å; L75-E77 VanDerWaalsContact C-N 3.35Å; L75-V78 PolarHBondContact O-N 3.06Å; L75-R79 WeakPolarHBondContact O-CB 3.4Å; L75-R79 PolarHBondContact O-N 2.89Å; L75-I109 HydrophobicContact CD1-CG2 3.85Å; L75-E110 WeakPolarHBondContact CB-OE1 3.48Å; L75-E110 HydrophobicContact CD1-CG 4.12Å
76V88.5Confident82.6Confident78 Ų7856.7 Ų56.747%0.47332%0.322SS..Hα-helixtrans-63.2-41.3172.9174.50000111.1R72 A73 R79 K80R72-V76 WeakPolarHBondContact O-CG2 3.49Å; R72-V76 PolarHBondContact O-N 3.16Å; A73-V76 PolarHBondContact O-N 3.35Å; V76-R79 PolarHBondContact O-N 3.03Å; V76-K80 WeakPolarHBondContact O-CB 3.23Å; V76-K80 PolarHBondContact O-N 2.81Å
77E88Confident83Confident95 Ų9560.3 Ų60.344%0.44434%0.338SS..Hα-helixtrans-64.3-44173.9-73.6-175.8-167.300112.4K52 A73 T74 L75 R79 K80 H81K52-E77 IonicContact NZ-OE2 3.96Å; K52-E77 PolarHBondContact NZ-OE2 2.98Å; A73-E77 PolarHBondContact O-N 3.45Å; A73-E77 VanDerWaalsContact O-N 3.08Å; T74-E77 PolarHBondContact O-N 2.8Å; L75-E77 VanDerWaalsContact C-N 3.35Å; E77-R79 VanDerWaalsContact C-N 3.34Å; E77-K80 WeakPolarHBondContact O-CB 3.18Å; E77-K80 PolarHBondContact O-N 2.95Å; E77-H81 PolarHBondContact O-CD2 3.48Å; E77-H81 PolarHBondContact O-N 2.79Å
78V90.4Very high83.1Confident0 Ų062.3 Ų62.30%033%0.331CS..Hα-helixtrans-59.8-47.9175.61780000110.3G49 K52 L53 T74 L75 K80 H81 L82 I106G49-V78 WeakPolarHBondContact O-CG1 3.43Å; K52-V78 HydrophobicContact CB-CG2 3.61Å; L53-V78 HydrophobicContact CB-CG1 4.03Å; L53-V78 HydrophobicContact CB-CG2 4.23Å; T74-V78 WeakPolarHBondContact O-CG2 3.48Å; T74-V78 PolarHBondContact O-N 3.05Å; L75-V78 PolarHBondContact O-N 3.06Å; V78-K80 VanDerWaalsContact C-N 3.28Å; V78-K80 PolarHBondContact O-N 3.24Å; V78-H81 PolarHBondContact O-N 3.5Å; V78-H81 VanDerWaalsContact O-N 3.15Å; V78-L82 HydrophobicContact CG1-CD1 3.97Å; V78-L82 HydrophobicContact CG1-CG 4.22Å; V78-L82 WeakPolarHBondContact O-CG 3.38Å; V78-L82 PolarHBondContact O-N 2.85Å; V78-I106 HydrophobicContact CB-CD1 4.05Å; V78-I106 HydrophobicContact CG1-CD1 3.25Å; V78-I106 HydrophobicContact CG1-CG1 4.28Å
79R90Very high83Confident59 Ų5968.8 Ų68.822%0.22335%0.347CS..Hα-helixtrans-57-43.9178.2-174.8177.5-79.5-88.317110.6L75 V76 E77 H81 L82 T83 M103 E110 E112L75-R79 WeakPolarHBondContact O-CB 3.4Å; L75-R79 PolarHBondContact O-N 2.89Å; V76-R79 PolarHBondContact O-N 3.03Å; E77-R79 VanDerWaalsContact C-N 3.34Å; R79-H81 PolarHBondContact O-N 2.88Å; R79-L82 PolarHBondContact O-N 2.94Å; R79-T83 WeakPolarHBondContact O-CB 3.28Å; R79-T83 PolarHBondContact O-N 3.48Å; R79-T83 PolarHBondContact O-OG1 3.31Å; R79-M103 HydrophobicContact CG-CE 4.43Å; R79-M103 HydrophobicContact CG-SD 4.21Å; R79-E110 IonicContact CZ-OE2 2.71Å; R79-E110 VanDerWaalsContact CZ-OE2 3.26Å; R79-E110 IonicContact NE-OE2 3.65Å; R79-E110 PolarHBondContact NE-OE2 3.04Å; R79-E110 VanDerWaalsContact NE-OE2 3.12Å; R79-E110 IonicContact NH2-OE2 3.55Å; R79-E110 PolarHBondContact NH2-OE2 3.21Å; R79-E112 IonicContact NH2-OE1 3.58Å; R79-E112 IonicContact NH2-OE2 2.71Å; R79-E112 PolarHBondContact NH2-OE2 3.42Å
80K90.2Very high83.3Confident160 Ų16068.5 Ų68.570%0.69635%0.352SS*.Hα-helixtrans-58.8-47175.3-176-179.2176.8-1770112.6V76 E77 V78 A84V76-K80 WeakPolarHBondContact O-CB 3.23Å; V76-K80 PolarHBondContact O-N 2.81Å; E77-K80 WeakPolarHBondContact O-CB 3.18Å; E77-K80 PolarHBondContact O-N 2.95Å; V78-K80 VanDerWaalsContact C-N 3.28Å; V78-K80 PolarHBondContact O-N 3.24Å; K80-A84 WeakPolarHBondContact O-CB 3.17Å; K80-A84 PolarHBondContact O-N 3.08Å
81H89.5Confident84.1Confident32 Ų3267.6 Ų67.615%0.14834%0.339CS..Hα-helixtrans-61.5-45.6177.5-73.3-60.5000111.6E45 K52 E77 V78 R79 A84 A85E45-H81 IonicContact OE2-CE1 3.87Å; E45-H81 IonicContact OE2-CG 2.95Å; E45-H81 IonicContact OE2-ND1 3.36Å; E45-H81 PolarHBondContact OE2-ND1 2.98Å; K52-H81 PolarHBondContact NZ-NE2 3.25Å; E77-H81 PolarHBondContact O-CD2 3.48Å; E77-H81 PolarHBondContact O-N 2.79Å; V78-H81 PolarHBondContact O-N 3.5Å; V78-H81 VanDerWaalsContact O-N 3.15Å; R79-H81 PolarHBondContact O-N 2.88Å; H81-A84 PolarHBondContact O-N 2.88Å; H81-A85 PolarHBondContact O-N 3.47Å; H81-A85 VanDerWaalsContact O-N 3.11Å
82L88.7Confident84.9Confident0 Ų068.5 Ų68.50%033%0.333CS..Hα-helixtrans-71.7-37.5-179.5-64.4-178.5000113.2L46 V78 R79 A84 A85 L86 L102 M103 I106L46-L82 HydrophobicContact CD1-CD2 3.77Å; V78-L82 HydrophobicContact CG1-CD1 3.97Å; V78-L82 HydrophobicContact CG1-CG 4.22Å; V78-L82 WeakPolarHBondContact O-CG 3.38Å; V78-L82 PolarHBondContact O-N 2.85Å; R79-L82 PolarHBondContact O-N 2.94Å; L82-A84 VanDerWaalsContact C-N 3.35Å; L82-A85 PolarHBondContact O-N 3.25Å; L82-L86 WeakPolarHBondContact O-CG 3.19Å; L82-L86 PolarHBondContact O-N 2.86Å; L82-L102 HydrophobicContact CD1-CB 3.69Å; L82-L102 HydrophobicContact CD2-CB 4.29Å; L82-L102 HydrophobicContact CD2-CD1 4.25Å; L82-M103 HydrophobicContact CB-CE 3.5Å; L82-M103 VanDerWaalsContact CB-CE 3.5Å; L82-I106 HydrophobicContact CD1-CD1 3.45Å; L82-I106 VanDerWaalsContact CD1-CD1 3.45Å
83T89.6Confident85.1Confident51 Ų5168 Ų6831%0.31335%0.347SS..Hα-helixtrans-63.8-41.9173.7-590000110.7R79 A85 L86 D87 M103R79-T83 WeakPolarHBondContact O-CB 3.28Å; R79-T83 PolarHBondContact O-N 3.48Å; R79-T83 PolarHBondContact O-OG1 3.31Å; T83-A85 VanDerWaalsContact C-N 3.3Å; T83-A85 PolarHBondContact O-N 3.48Å; T83-L86 PolarHBondContact O-N 3.15Å; T83-D87 VanDerWaalsContact CG2-OD2 3.31Å; T83-D87 WeakPolarHBondContact CG2-OD2 3.31Å; T83-D87 WeakPolarHBondContact O-CB 3.35Å; T83-D87 VanDerWaalsContact O-CG 3.3Å; T83-D87 PolarHBondContact O-N 3.24Å; T83-M103 WeakPolarHBondContact OG1-CE 3.09Å
84A85.7Confident85.2Confident22 Ų2267.7 Ų67.718%0.18233%0.334CS..Hα-helixtrans-59.8-39.7174.500000112.4K80 H81 L82 R88K80-A84 WeakPolarHBondContact O-CB 3.17Å; K80-A84 PolarHBondContact O-N 3.08Å; H81-A84 PolarHBondContact O-N 2.88Å; L82-A84 VanDerWaalsContact C-N 3.35Å; A84-R88 WeakPolarHBondContact O-CD 3.42Å; A84-R88 WeakPolarHBondContact O-CG 3.19Å
85A84.9Confident85.3Confident0 Ų066.2 Ų66.20%032%0.321CS..Hα-helixtrans-68.4-35.7176.200000113.2E45 L46 H81 L82 T83 L91E45-A85 HydrophobicContact CB-CB 4.43Å; L46-A85 HydrophobicContact CB-CB 4.4Å; H81-A85 PolarHBondContact O-N 3.47Å; H81-A85 VanDerWaalsContact O-N 3.11Å; L82-A85 PolarHBondContact O-N 3.25Å; T83-A85 VanDerWaalsContact C-N 3.3Å; T83-A85 PolarHBondContact O-N 3.48Å; A85-L91 HydrophobicContact CB-CD1 4.04Å
86L85.4Confident85.4Confident31 Ų3168.1 Ų68.116%0.16233%0.332CS..Hα-helixtrans-79-41.4-179-74.6170000113.4L82 T83 R88 R89 L96 A99 M103L82-L86 WeakPolarHBondContact O-CG 3.19Å; L82-L86 PolarHBondContact O-N 2.86Å; T83-L86 PolarHBondContact O-N 3.15Å; L86-R88 VanDerWaalsContact C-N 3.33Å; L86-R88 PolarHBondContact O-N 3.41Å; L86-R89 WeakPolarHBondContact O-CG 3.17Å; L86-R89 PolarHBondContact O-N 2.68Å; L86-L96 HydrophobicContact CD2-CD2 4.48Å; L86-A99 HydrophobicContact CD2-CB 3.69Å; L86-A99 HydrophobicContact CG-CB 3.91Å; L86-M103 HydrophobicContact CD1-CB 4.34Å; L86-M103 HydrophobicContact CD1-CE 4.08Å
87D83Confident85.4Confident124 Ų12467 Ų6766%0.66332%0.321SS*.Hα-helixtrans-68.3-32.8-174.2-74-13.7000112.6T83T83-D87 VanDerWaalsContact CG2-OD2 3.31Å; T83-D87 WeakPolarHBondContact CG2-OD2 3.31Å; T83-D87 WeakPolarHBondContact O-CB 3.35Å; T83-D87 VanDerWaalsContact O-CG 3.3Å; T83-D87 PolarHBondContact O-N 3.24Å
88R76.3Confident85.6Confident131 Ų13162.6 Ų62.649%0.49430%0.3SS..THydrogen-bonded Turntrans-81.3-19.7-175.7-65.6173.6-177.8174.64.1113.7D42 A84 L86 N90D42-R88 WeakPolarHBondContact OD1-CD 3.49Å; D42-R88 IonicContact OD1-CZ 3.9Å; D42-R88 IonicContact OD1-NE 2.85Å; D42-R88 IonicContact OD1-NH1 3.72Å; D42-R88 PolarHBondContact OD1-NH1 2.93Å; D42-R88 WeakPolarHBondContact OD2-CB 3.49Å; A84-R88 WeakPolarHBondContact O-CD 3.42Å; A84-R88 WeakPolarHBondContact O-CG 3.19Å; L86-R88 VanDerWaalsContact C-N 3.33Å; L86-R88 PolarHBondContact O-N 3.41Å; R88-N90 VanDerWaalsContact O-CG 3.3Å; R88-N90 PolarHBondContact O-N 3.2Å; R88-N90 PolarHBondContact O-ND2 2.94Å; R88-N90 PolarHBondContact O-OD1 3.17Å
89R74.1Confident85.6Confident202 Ų20262.6 Ų62.676%0.76230%0.3SS*.  trans47.624.7178.1-63.3-168.1179-164.10.1116.6L86 L91L86-R89 WeakPolarHBondContact O-CG 3.17Å; L86-R89 PolarHBondContact O-N 2.68Å; R89-L91 VanDerWaalsContact C-N 3.3Å
90N79.6Confident85.7Confident78 Ų7860.6 Ų60.642%0.41730%0.295SS..  trans-87.40.5178.9-55.3-52000113.8D42 R88D42-N90 WeakPolarHBondContact OD2-CB 3.39Å; D42-N90 PolarHBondContact OD2-ND2 3.42Å; R88-N90 VanDerWaalsContact O-CG 3.3Å; R88-N90 PolarHBondContact O-N 3.2Å; R88-N90 PolarHBondContact O-ND2 2.94Å; R88-N90 PolarHBondContact O-OD1 3.17Å
91L82Confident85.8Confident14 Ų1453.4 Ų53.47%0.07327%0.265CS..SBendtrans-83.2152.9179.8-74.1176.1000111.7D42 L43 L46 A85 R89 L96D42-L91 HydrophobicContact CB-CD2 4.13Å; D42-L91 HydrophobicContact CB-CG 4.04Å; L43-L91 HydrophobicContact CB-CD2 3.95Å; L43-L91 HydrophobicContact CD1-CD2 4.45Å; L46-L91 HydrophobicContact CD2-CD1 4.42Å; A85-L91 HydrophobicContact CB-CD1 4.04Å; R89-L91 VanDerWaalsContact C-N 3.3Å; L91-L96 HydrophobicContact CB-CD2 3.82Å; L91-L96 HydrophobicContact CB-CG 3.8Å; L91-L96 HydrophobicContact CD1-CD2 4.32Å
92K84.1Confident86Confident136 Ų13652 Ų5259%0.59126%0.258SS*.  trans-58.8151.3167.8-64.5179.7-177169.30109.5D94 Y95 L96K92-D94 PolarHBondContact O-N 2.93Å; K92-D94 VanDerWaalsContact O-N 3.1Å; K92-Y95 HydrophobicContact CB-CD2 3.94Å; K92-Y95 HydrophobicContact CB-CE2 4.48Å; K92-Y95 HydrophobicContact CD-CD2 4.41Å; K92-Y95 HydrophobicContact CD-CE2 4.14Å; K92-Y95 HydrophobicContact CG-CD2 4.37Å; K92-Y95 PolarHBondContact O-N 3.17Å; K92-L96 PolarHBondContact O-N 3.4Å
93A84.8Confident86.1Confident71 Ų7152.2 Ų52.259%0.58726%0.259SS*.Hα-helixtrans-50.8-39.8-179.500000112.8L96 Q97A93-L96 PolarHBondContact O-N 3.42Å; A93-Q97 WeakPolarHBondContact O-CG 3.37Å; A93-Q97 PolarHBondContact O-N 3.39Å
94D84.2Confident86.3Confident73 Ų7349.8 Ų49.839%0.3924%0.244SC..Hα-helixtrans-56.8-48.5174.5-72.5-42.8000113.7K92 Q97 E98 R137K92-D94 PolarHBondContact O-N 2.93Å; K92-D94 VanDerWaalsContact O-N 3.1Å; D94-Q97 WeakPolarHBondContact O-CB 3.38Å; D94-Q97 PolarHBondContact O-N 3.28Å; D94-E98 WeakPolarHBondContact O-CG 3.42Å; D94-E98 PolarHBondContact O-N 2.94Å; D94-R137 VanDerWaalsContact CB-NH1 3.27Å; D94-R137 IonicContact OD1-CZ 3.06Å; D94-R137 VanDerWaalsContact OD1-CZ 3.28Å; D94-R137 IonicContact OD1-NH1 3.68Å; D94-R137 PolarHBondContact OD1-NH1 3.45Å; D94-R137 IonicContact OD1-NH2 2.91Å; D94-R137 PolarHBondContact OD1-NH2 2.96Å; D94-R137 IonicContact OD2-NH1 3.64Å
95Y86.8Confident86.6Confident33 Ų3349 Ų4913%0.12924%0.237CC..Hα-helixtrans-73.8-28.7179.9-63.9-52.7000112.4L43 L46 K92 E98 A99L43-Y95 HydrophobicContact CD1-CD1 3.99Å; L43-Y95 HydrophobicContact CD1-CD2 4.06Å; L43-Y95 HydrophobicContact CD1-CE1 4.04Å; L43-Y95 HydrophobicContact CD1-CE2 4.09Å; L43-Y95 HydrophobicContact CD1-CG 4.02Å; L46-Y95 HydrophobicContact CD2-CD1 4.13Å; L46-Y95 HydrophobicContact CD2-CG 4.33Å; K92-Y95 HydrophobicContact CB-CD2 3.94Å; K92-Y95 HydrophobicContact CB-CE2 4.48Å; K92-Y95 HydrophobicContact CD-CD2 4.41Å; K92-Y95 HydrophobicContact CD-CE2 4.14Å; K92-Y95 HydrophobicContact CG-CD2 4.37Å; K92-Y95 PolarHBondContact O-N 3.17Å; Y95-E98 PolarHBondContact O-N 3.36Å; Y95-A99 WeakPolarHBondContact O-CB 3.49Å; Y95-A99 PolarHBondContact O-N 2.91Å
96L87.4Confident86.9Confident41 Ų4149 Ų4922%0.21524%0.237CC..Hα-helixtrans-66.6-40.2170.4-70.7174.1000111.5L86 L91 K92 A93 A99 S100L86-L96 HydrophobicContact CD2-CD2 4.48Å; L91-L96 HydrophobicContact CB-CD2 3.82Å; L91-L96 HydrophobicContact CB-CG 3.8Å; L91-L96 HydrophobicContact CD1-CD2 4.32Å; K92-L96 PolarHBondContact O-N 3.4Å; A93-L96 PolarHBondContact O-N 3.42Å; L96-A99 PolarHBondContact O-N 3.07Å; L96-S100 PolarHBondContact O-N 2.93Å; L96-S100 VanDerWaalsContact O-N 3.07Å; L96-S100 PolarHBondContact O-OG 3.03Å
97Q89.8Confident87.2Confident54 Ų5447.6 Ų47.625%0.25223%0.229SC..Hα-helixtrans-61.9-47.7171.9-70.3172.4-20.300110.5A93 D94 A99 S100 L101 V123A93-Q97 WeakPolarHBondContact O-CG 3.37Å; A93-Q97 PolarHBondContact O-N 3.39Å; D94-Q97 WeakPolarHBondContact O-CB 3.38Å; D94-Q97 PolarHBondContact O-N 3.28Å; Q97-A99 VanDerWaalsContact C-N 3.34Å; Q97-A99 PolarHBondContact O-N 2.91Å; Q97-S100 PolarHBondContact O-N 3.41Å; Q97-L101 WeakPolarHBondContact O-CG 3.39Å; Q97-L101 PolarHBondContact O-N 3.19Å; Q97-V123 HydrophobicContact CB-CG1 4.2Å; Q97-V123 HydrophobicContact CG-CG1 4.17Å
98E91.1Very high87.5Confident2 Ų242.9 Ų42.91%0.00920%0.203CC..Hα-helixtrans-55.7-46.2176.7-72.8179.1-162.900112.2R18 L46 D94 Y95 S100 L101 L102 Y136 M140R18-E98 IonicContact CZ-OE2 2.83Å; R18-E98 VanDerWaalsContact CZ-OE2 3.3Å; R18-E98 IonicContact NH1-OE1 2.6Å; R18-E98 IonicContact NH1-OE2 2.62Å; R18-E98 PolarHBondContact NH1-OE2 3.21Å; R18-E98 IonicContact NH2-OE2 2.84Å; R18-E98 PolarHBondContact NH2-OE2 3.08Å; L46-E98 HydrophobicContact CD2-CB 4.37Å; D94-E98 WeakPolarHBondContact O-CG 3.42Å; D94-E98 PolarHBondContact O-N 2.94Å; Y95-E98 PolarHBondContact O-N 3.36Å; E98-S100 PolarHBondContact O-N 3.22Å; E98-L101 PolarHBondContact O-N 3.42Å; E98-L102 WeakPolarHBondContact O-CG 3.48Å; E98-L102 PolarHBondContact O-N 2.91Å; E98-Y136 WeakPolarHBondContact OE1-CE2 3.47Å; E98-Y136 PolarHBondContact OE1-OH 2.88Å; E98-M140 HydrophobicContact CB-CE 3.78Å; E98-M140 HydrophobicContact CG-CE 3.87Å; E98-M140 HydrophobicContact CG-SD 4.07Å
99A90.4Very high88.1Confident0 Ų037 Ų370%018%0.181CC..Hα-helixtrans-60.5-42.8177.100000112.3L46 L86 Y95 L96 Q97 L102 M103L46-A99 HydrophobicContact CD1-CB 3.77Å; L86-A99 HydrophobicContact CD2-CB 3.69Å; L86-A99 HydrophobicContact CG-CB 3.91Å; Y95-A99 WeakPolarHBondContact O-CB 3.49Å; Y95-A99 PolarHBondContact O-N 2.91Å; L96-A99 PolarHBondContact O-N 3.07Å; Q97-A99 VanDerWaalsContact C-N 3.34Å; Q97-A99 PolarHBondContact O-N 2.91Å; A99-L102 PolarHBondContact O-N 3.33Å; A99-M103 WeakPolarHBondContact O-CB 3.41Å; A99-M103 PolarHBondContact O-N 3.33Å
100S91.4Very high88.8Confident17 Ų1728.3 Ų28.312%0.11915%0.149CC..Hα-helixtrans-65.9-38.6176.3-690000112.9L96 Q97 E98 M103 A104 V123L96-S100 PolarHBondContact O-N 2.93Å; L96-S100 VanDerWaalsContact O-N 3.07Å; L96-S100 PolarHBondContact O-OG 3.03Å; Q97-S100 PolarHBondContact O-N 3.41Å; E98-S100 PolarHBondContact O-N 3.22Å; S100-M103 PolarHBondContact O-N 3.01Å; S100-A104 WeakPolarHBondContact O-CB 3.47Å; S100-A104 PolarHBondContact O-N 3.48Å; S100-V123 VanDerWaalsContact CB-CG2 3.44Å
101L93.6Very high89.1Confident10 Ų1025.7 Ų25.75%0.05214%0.141CC..Hα-helixtrans-65.3-41.5175.3-65.9-179.8000111.8Q97 E98 A104 K105 Y120 V123 L125 L128 M140 A144Q97-L101 WeakPolarHBondContact O-CG 3.39Å; Q97-L101 PolarHBondContact O-N 3.19Å; E98-L101 PolarHBondContact O-N 3.42Å; L101-A104 PolarHBondContact O-N 3.1Å; L101-K105 PolarHBondContact O-N 3.12Å; L101-Y120 HydrophobicContact CD2-CD1 3.8Å; L101-Y120 HydrophobicContact CD2-CE1 3.79Å; L101-V123 HydrophobicContact CD2-CB 4.4Å; L101-V123 HydrophobicContact CD2-CG1 4Å; L101-V123 HydrophobicContact CD2-CG2 4.44Å; L101-V123 HydrophobicContact CG-CG1 4.4Å; L101-L125 HydrophobicContact CD2-CD2 3.53Å; L101-L128 HydrophobicContact CD1-CD1 4.31Å; L101-M140 HydrophobicContact CB-CE 4.32Å; L101-M140 HydrophobicContact CD1-CE 4.49Å; L101-A144 HydrophobicContact CD1-CB 4.46Å; L101-A144 HydrophobicContact CD2-CB 3.86Å
102L92.8Very high89.5Confident1 Ų128.5 Ų28.51%0.00515%0.154CC..Hα-helixtrans-67.8-38.4176-67.4171.1000111.6L46 E50 L53 L82 E98 A99 K105 I106 M140L46-L102 HydrophobicContact CD1-CD1 3.81Å; E50-L102 HydrophobicContact CB-CD1 3.66Å; E50-L102 HydrophobicContact CG-CD1 3.83Å; E50-L102 HydrophobicContact CG-CD2 4.04Å; L53-L102 HydrophobicContact CD2-CD2 4.22Å; L82-L102 HydrophobicContact CD1-CB 3.69Å; L82-L102 HydrophobicContact CD2-CB 4.29Å; L82-L102 HydrophobicContact CD2-CD1 4.25Å; E98-L102 WeakPolarHBondContact O-CG 3.48Å; E98-L102 PolarHBondContact O-N 2.91Å; A99-L102 PolarHBondContact O-N 3.33Å; L102-K105 WeakPolarHBondContact O-CB 3.34Å; L102-K105 PolarHBondContact O-N 3.37Å; L102-I106 WeakPolarHBondContact O-CG1 3.46Å; L102-I106 PolarHBondContact O-N 2.85Å; L102-M140 HydrophobicContact CD1-CE 4.32Å; L102-M140 HydrophobicContact CD2-CE 4.15Å; L102-M140 HydrophobicContact CG-CE 3.9Å
103M91.9Very high89.8Confident5 Ų524.2 Ų24.23%0.02513%0.134CC..Hα-helixtrans-61.1-45.5173.3-170.662.474.900111.1R79 L82 T83 L86 A99 S100 K105 I106 C107R79-M103 HydrophobicContact CG-CE 4.43Å; R79-M103 HydrophobicContact CG-SD 4.21Å; L82-M103 HydrophobicContact CB-CE 3.5Å; L82-M103 VanDerWaalsContact CB-CE 3.5Å; T83-M103 WeakPolarHBondContact OG1-CE 3.09Å; L86-M103 HydrophobicContact CD1-CB 4.34Å; L86-M103 HydrophobicContact CD1-CE 4.08Å; A99-M103 WeakPolarHBondContact O-CB 3.41Å; A99-M103 PolarHBondContact O-N 3.33Å; S100-M103 PolarHBondContact O-N 3.01Å; M103-K105 VanDerWaalsContact C-N 3.29Å; M103-K105 PolarHBondContact O-N 3.47Å; M103-I106 PolarHBondContact O-N 3.43Å; M103-I106 VanDerWaalsContact O-N 3.15Å; M103-C107 PolarHBondContact O-N 3.32Å; M103-C107 PolarHBondContact O-SG 2.89Å
104A92.6Very high90Very high0 Ų024.1 Ų24.10%013%0.129CC..Hα-helixtrans-59.7-39.2175.800000112.5S100 L101 C107 Y108 A116 H119 Y120S100-A104 WeakPolarHBondContact O-CB 3.47Å; S100-A104 PolarHBondContact O-N 3.48Å; L101-A104 PolarHBondContact O-N 3.1Å; A104-C107 PolarHBondContact O-N 3.28Å; A104-Y108 PolarHBondContact O-N 3.09Å; A104-A116 HydrophobicContact CB-CB 4.43Å; A104-A116 WeakPolarHBondContact O-CB 3.48Å; A104-H119 HydrophobicContact CB-CB 3.75Å; A104-Y120 HydrophobicContact CB-CD1 4Å; A104-Y120 HydrophobicContact CB-CD2 4.22Å; A104-Y120 HydrophobicContact CB-CE1 3.51Å; A104-Y120 HydrophobicContact CB-CE2 3.77Å; A104-Y120 HydrophobicContact CB-CG 4.32Å
105K91.8Very high90.2Very high6 Ų624.1 Ų24.13%0.02613%0.129CC..Hα-helixtrans-63.6-40175.6-170.5-177.4-69.3-179.30112.2L53 L57 L101 L102 M103 Y108 I109 E143 F226L53-K105 HydrophobicContact CD2-CD 4.2Å; L57-K105 HydrophobicContact CD1-CD 4.4Å; L101-K105 PolarHBondContact O-N 3.12Å; L102-K105 WeakPolarHBondContact O-CB 3.34Å; L102-K105 PolarHBondContact O-N 3.37Å; M103-K105 VanDerWaalsContact C-N 3.29Å; M103-K105 PolarHBondContact O-N 3.47Å; K105-Y108 PolarHBondContact O-N 2.74Å; K105-I109 HydrophobicContact CG-CD1 4.29Å; K105-I109 WeakPolarHBondContact O-CD1 3.38Å; K105-I109 VanDerWaalsContact O-CG1 3.29Å; K105-I109 WeakPolarHBondContact O-CG1 3.49Å; K105-I109 PolarHBondContact O-N 3.31Å; K105-I109 VanDerWaalsContact O-N 3.14Å; K105-E143 VanDerWaalsContact NZ-CD 3.34Å; K105-E143 IonicContact NZ-OE1 3.62Å; K105-E143 IonicContact NZ-OE2 3.56Å; K105-E143 PolarHBondContact NZ-OE2 3.11Å; K105-F226 HydrophobicContact CD-CE2 4.1Å; K105-F226 HydrophobicContact CG-CE2 4.21Å; K105-F226 HydrophobicContact CG-CZ 4.21Å
106I92.3Very high90.4Very high0 Ų022.6 Ų22.60%012%0.123CC..Hα-helixtrans-66.3-45.7175.2-65.7165.8000110.9L53 V78 L82 L102 M103 Y108 I109 E110L53-I106 HydrophobicContact CD1-CG1 3.9Å; L53-I106 HydrophobicContact CD2-CD1 4.33Å; L53-I106 HydrophobicContact CD2-CG1 3.86Å; V78-I106 HydrophobicContact CB-CD1 4.05Å; V78-I106 HydrophobicContact CG1-CD1 3.25Å; V78-I106 HydrophobicContact CG1-CG1 4.28Å; L82-I106 HydrophobicContact CD1-CD1 3.45Å; L82-I106 VanDerWaalsContact CD1-CD1 3.45Å; L102-I106 WeakPolarHBondContact O-CG1 3.46Å; L102-I106 PolarHBondContact O-N 2.85Å; M103-I106 PolarHBondContact O-N 3.43Å; M103-I106 VanDerWaalsContact O-N 3.15Å; I106-Y108 PolarHBondContact O-N 3.02Å; I106-I109 PolarHBondContact O-N 3.17Å; I106-E110 HydrophobicContact CG2-CG 4.19Å; I106-E110 PolarHBondContact O-N 2.97Å
107C90.6Very high90.6Very high1 Ų122.1 Ų22.11%0.00712%0.121CC..Hα-helixtrans-54.6-42176.3-68.50000111M103 A104 E110 G111 E112 N115 A116M103-C107 PolarHBondContact O-N 3.32Å; M103-C107 PolarHBondContact O-SG 2.89Å; A104-C107 PolarHBondContact O-N 3.28Å; C107-E110 PolarHBondContact O-N 3.49Å; C107-G111 PolarHBondContact O-N 3.44Å; C107-E112 HydrophobicContact CB-CB 4.1Å; C107-E112 WeakPolarHBondContact O-CA 3.11Å; C107-E112 PolarHBondContact O-N 3.47Å; C107-N115 HydrophobicContact CB-CB 4.37Å; C107-A116 HydrophobicContact CB-CB 3.82Å
108Y90.4Very high90.6Very high25 Ų2523.7 Ų23.710%0.09813%0.131CC..Hα-helixtrans-60.5-46.9172.6172.4-99.2000113.1A104 K105 I106 E110 G111 Y113 T147 L150 C151 F226A104-Y108 PolarHBondContact O-N 3.09Å; K105-Y108 PolarHBondContact O-N 2.74Å; I106-Y108 PolarHBondContact O-N 3.02Å; Y108-E110 VanDerWaalsContact C-N 3.29Å; Y108-E110 PolarHBondContact O-N 3.47Å; Y108-G111 PolarHBondContact O-N 3.01Å; Y108-G111 VanDerWaalsContact O-N 3.15Å; Y108-Y113 AromaticContact CD2-CD1 3.81Å; Y108-Y113 HydrophobicContact CD2-CD1 3.81Å; Y108-Y113 AromaticContact CD2-CE1 3.76Å; Y108-Y113 HydrophobicContact CD2-CE1 3.76Å; Y108-Y113 HydrophobicContact CE2-CD1 4.29Å; Y108-Y113 AromaticContact CE2-CE1 3.9Å; Y108-Y113 HydrophobicContact CE2-CE1 3.9Å; Y108-T147 VanDerWaalsContact CB-CG2 3.49Å; Y108-T147 HydrophobicContact CD1-CG2 4.08Å; Y108-T147 HydrophobicContact CD2-CG2 4.12Å; Y108-T147 HydrophobicContact CG-CG2 3.62Å; Y108-L150 HydrophobicContact CD2-CB 4.37Å; Y108-L150 HydrophobicContact CE1-CD1 4.36Å; Y108-L150 HydrophobicContact CE2-CB 3.61Å; Y108-L150 HydrophobicContact CE2-CD1 4.38Å; Y108-C151 VanDerWaalsContact CD2-SG 3.59Å; Y108-F226 AromaticContact CD1-CE1 3.73Å; Y108-F226 HydrophobicContact CD1-CE1 3.73Å; Y108-F226 AromaticContact CD1-CZ 3.93Å; Y108-F226 HydrophobicContact CD1-CZ 3.93Å; Y108-F226 AromaticContact CE1-CE1 3.59Å; Y108-F226 HydrophobicContact CE1-CE1 3.59Å; Y108-F226 HydrophobicContact CE1-CZ 4.01Å
109I88.5Confident90.5Very high7 Ų725.5 Ų25.54%0.03614%0.139CC..Hα-helixtrans-62.8-37.2-179-66.4161.6000111.6L53 L57 I62 R69 L75 K105 I106 G111L53-I109 HydrophobicContact CD1-CD1 3.97Å; L57-I109 HydrophobicContact CD1-CD1 4.41Å; L57-I109 HydrophobicContact CD2-CD1 3.85Å; L57-I109 HydrophobicContact CG-CD1 4.47Å; I62-I109 HydrophobicContact CD1-CG1 4.18Å; R69-I109 HydrophobicContact CB-CG2 4.06Å; R69-I109 HydrophobicContact CG-CG2 4.38Å; R69-I109 PolarHBondContact N-O 3.19Å; L75-I109 HydrophobicContact CD1-CG2 3.85Å; K105-I109 HydrophobicContact CG-CD1 4.29Å; K105-I109 WeakPolarHBondContact O-CD1 3.38Å; K105-I109 VanDerWaalsContact O-CG1 3.29Å; K105-I109 WeakPolarHBondContact O-CG1 3.49Å; K105-I109 PolarHBondContact O-N 3.31Å; K105-I109 VanDerWaalsContact O-N 3.14Å; I106-I109 PolarHBondContact O-N 3.17Å; I109-G111 VanDerWaalsContact C-N 3.32Å
110E88.6Confident90.6Very high20 Ų2025.7 Ų25.79%0.09314%0.14CC..Hα-helixtrans-80.4-12.9178.9-66.7-174.9155.600113L75 R79 I106 C107 Y108L75-E110 WeakPolarHBondContact CB-OE1 3.48Å; L75-E110 HydrophobicContact CD1-CG 4.12Å; R79-E110 IonicContact CZ-OE2 2.71Å; R79-E110 VanDerWaalsContact CZ-OE2 3.26Å; R79-E110 IonicContact NE-OE2 3.65Å; R79-E110 PolarHBondContact NE-OE2 3.04Å; R79-E110 VanDerWaalsContact NE-OE2 3.12Å; R79-E110 IonicContact NH2-OE2 3.55Å; R79-E110 PolarHBondContact NH2-OE2 3.21Å; I106-E110 HydrophobicContact CG2-CG 4.19Å; I106-E110 PolarHBondContact O-N 2.97Å; C107-E110 PolarHBondContact O-N 3.49Å; Y108-E110 VanDerWaalsContact C-N 3.29Å; Y108-E110 PolarHBondContact O-N 3.47Å
111G85.9Confident90.4Very high24 Ų2428.9 Ų28.925%0.24716%0.162CC..THydrogen-bonded Turntrans95.38.2177.700000114.9C107 Y108 I109 Y113C107-G111 PolarHBondContact O-N 3.44Å; Y108-G111 PolarHBondContact O-N 3.01Å; Y108-G111 VanDerWaalsContact O-N 3.15Å; I109-G111 VanDerWaalsContact C-N 3.32Å; G111-Y113 VanDerWaalsContact C-N 3.32Å; G111-Y113 PolarHBondContact O-N 3.25Å; G111-Y113 VanDerWaalsContact O-N 3.14Å
112E89.8Confident90Very high73 Ų7335 Ų3534%0.34119%0.191SC..  trans-85.566.3176.8-61.7-178178.800111.3R79 C107 S114 N115 A116R79-E112 IonicContact NH2-OE1 3.58Å; R79-E112 IonicContact NH2-OE2 2.71Å; R79-E112 PolarHBondContact NH2-OE2 3.42Å; C107-E112 HydrophobicContact CB-CB 4.1Å; C107-E112 WeakPolarHBondContact O-CA 3.11Å; C107-E112 PolarHBondContact O-N 3.47Å; E112-S114 PolarHBondContact O-N 3Å; E112-N115 HydrophobicContact CB-CB 4.13Å; E112-N115 PolarHBondContact O-N 2.9Å; E112-N115 PolarHBondContact OE2-ND2 3.49Å; E112-A116 PolarHBondContact O-N 3.14Å; E112-A116 VanDerWaalsContact O-N 3.13Å
113Y90.3Very high89.8Confident45 Ų4535.7 Ų35.718%0.17620%0.195CC..Hα-helixtrans-62.8-37.8-172.6-50.5-55.9000113.9Y108 G111 A116 L117 Q154Y108-Y113 AromaticContact CD2-CD1 3.81Å; Y108-Y113 HydrophobicContact CD2-CD1 3.81Å; Y108-Y113 AromaticContact CD2-CE1 3.76Å; Y108-Y113 HydrophobicContact CD2-CE1 3.76Å; Y108-Y113 HydrophobicContact CE2-CD1 4.29Å; Y108-Y113 AromaticContact CE2-CE1 3.9Å; Y108-Y113 HydrophobicContact CE2-CE1 3.9Å; G111-Y113 VanDerWaalsContact C-N 3.32Å; G111-Y113 PolarHBondContact O-N 3.25Å; G111-Y113 VanDerWaalsContact O-N 3.14Å; Y113-A116 WeakPolarHBondContact O-CB 3.26Å; Y113-A116 PolarHBondContact O-N 3.13Å; Y113-L117 WeakPolarHBondContact O-CG 3.4Å; Y113-L117 PolarHBondContact O-N 3.11Å; Y113-L117 VanDerWaalsContact O-N 3.12Å; Y113-Q154 HydrophobicContact CD1-CB 4.3Å; Y113-Q154 HydrophobicContact CD1-CG 4.4Å; Y113-Q154 HydrophobicContact CD2-CB 3.58Å; Y113-Q154 HydrophobicContact CD2-CG 4.33Å; Y113-Q154 HydrophobicContact CE1-CB 4.31Å; Y113-Q154 HydrophobicContact CE1-CG 4.05Å; Y113-Q154 HydrophobicContact CE2-CB 3.57Å; Y113-Q154 HydrophobicContact CE2-CG 3.95Å; Y113-Q154 HydrophobicContact CG-CB 3.94Å
114S88.8Confident89.6Confident70 Ų7038.8 Ų38.849%0.4921%0.211SC..Hα-helixtrans-64.6-46178.4-51.70000111.7E112 A116 L117 D118E112-S114 PolarHBondContact O-N 3Å; S114-A116 VanDerWaalsContact C-N 3.27Å; S114-A116 PolarHBondContact O-N 3.29Å; S114-L117 PolarHBondContact O-N 2.99Å; S114-L117 VanDerWaalsContact O-N 3.09Å; S114-D118 PolarHBondContact O-N 3.19Å
115N89.4Confident89.3Confident73 Ų7339.1 Ų39.139%0.3921%0.213SC..Hα-helixtrans-61.6-37.9177.4-64.3-9000111.3C107 E112 D118 H119C107-N115 HydrophobicContact CB-CB 4.37Å; E112-N115 HydrophobicContact CB-CB 4.13Å; E112-N115 PolarHBondContact O-N 2.9Å; E112-N115 PolarHBondContact OE2-ND2 3.49Å; N115-D118 PolarHBondContact O-N 2.99Å; N115-H119 PolarHBondContact O-CD2 3.16Å; N115-H119 PolarHBondContact O-N 3.25Å; N115-H119 VanDerWaalsContact O-N 3.12Å
116A91.3Very high89Confident0 Ų043.2 Ų43.20%024%0.235CC..Hα-helixtrans-62.4-41.9174.900000112.1A104 C107 E112 Y113 S114 H119 Y120A104-A116 HydrophobicContact CB-CB 4.43Å; A104-A116 WeakPolarHBondContact O-CB 3.48Å; C107-A116 HydrophobicContact CB-CB 3.82Å; E112-A116 PolarHBondContact O-N 3.14Å; E112-A116 VanDerWaalsContact O-N 3.13Å; Y113-A116 WeakPolarHBondContact O-CB 3.26Å; Y113-A116 PolarHBondContact O-N 3.13Å; S114-A116 VanDerWaalsContact C-N 3.27Å; S114-A116 PolarHBondContact O-N 3.29Å; A116-H119 PolarHBondContact O-N 2.62Å; A116-Y120 HydrophobicContact CB-CE2 4.46Å; A116-Y120 WeakPolarHBondContact O-CD2 3.5Å; A116-Y120 PolarHBondContact O-N 2.95Å; A116-Y120 VanDerWaalsContact O-N 3.08Å
117L90.3Very high88.7Confident32 Ų3248.8 Ų48.817%0.16827%0.265CS..Hα-helixtrans-66.8-36.4176.6-68.7179.9000112.6Y113 S114 H119 Y120 S121 K148 C151 L152 I155Y113-L117 WeakPolarHBondContact O-CG 3.4Å; Y113-L117 PolarHBondContact O-N 3.11Å; Y113-L117 VanDerWaalsContact O-N 3.12Å; S114-L117 PolarHBondContact O-N 2.99Å; S114-L117 VanDerWaalsContact O-N 3.09Å; L117-H119 VanDerWaalsContact C-N 3.34Å; L117-Y120 PolarHBondContact O-N 3.5Å; L117-S121 WeakPolarHBondContact O-CB 3.47Å; L117-S121 PolarHBondContact O-N 2.89Å; L117-S121 PolarHBondContact O-OG 3.47Å; L117-K148 HydrophobicContact CD2-CG 3.89Å; L117-C151 HydrophobicContact CD1-CB 4.44Å; L117-C151 HydrophobicContact CD2-CB 3.75Å; L117-C151 HydrophobicContact CG-CB 3.89Å; L117-L152 HydrophobicContact CD1-CD2 3.8Å; L117-L152 HydrophobicContact CD1-CG 4.41Å; L117-L152 HydrophobicContact CD2-CD2 4.11Å; L117-L152 HydrophobicContact CD2-CG 4Å; L117-I155 HydrophobicContact CD1-CD1 3.42Å; L117-I155 VanDerWaalsContact CD1-CD1 3.42Å; L117-I155 HydrophobicContact CG-CD1 4.42Å
118D90Very high88.6Confident87 Ų8749.2 Ų49.247%0.46527%0.267SS..Hα-helixtrans-62.9-41.5175-68.8-24.6000111.6S114 N115 S121 Q122S114-D118 PolarHBondContact O-N 3.19Å; N115-D118 PolarHBondContact O-N 2.99Å; D118-S121 PolarHBondContact O-N 3.02Å; D118-S121 PolarHBondContact O-OG 2.86Å; D118-Q122 WeakPolarHBondContact O-CG 3.44Å; D118-Q122 PolarHBondContact O-N 3.48Å
119H90.3Very high88.4Confident39 Ų3955 Ų5518%0.18130%0.295CS..Hα-helixtrans-65-40.4173.8-75.4-60.6000112.4A104 N115 A116 L117 Q122 V123A104-H119 HydrophobicContact CB-CB 3.75Å; N115-H119 PolarHBondContact O-CD2 3.16Å; N115-H119 PolarHBondContact O-N 3.25Å; N115-H119 VanDerWaalsContact O-N 3.12Å; A116-H119 PolarHBondContact O-N 2.62Å; L117-H119 VanDerWaalsContact C-N 3.34Å; H119-Q122 PolarHBondContact O-N 3.07Å; H119-V123 WeakPolarHBondContact O-CG2 3.48Å; H119-V123 PolarHBondContact O-N 3.39Å; H119-V123 VanDerWaalsContact O-N 3.16Å
120Y91.3Very high88.4Confident4 Ų455.1 Ų55.12%0.01630%0.296CS..Hα-helixtrans-67.9-34.9176.5-68.7-47.7000113.2L101 A104 A116 L117 N124 L125 A144 T147 K148L101-Y120 HydrophobicContact CD2-CD1 3.8Å; L101-Y120 HydrophobicContact CD2-CE1 3.79Å; A104-Y120 HydrophobicContact CB-CD1 4Å; A104-Y120 HydrophobicContact CB-CD2 4.22Å; A104-Y120 HydrophobicContact CB-CE1 3.51Å; A104-Y120 HydrophobicContact CB-CE2 3.77Å; A104-Y120 HydrophobicContact CB-CG 4.32Å; A116-Y120 HydrophobicContact CB-CE2 4.46Å; A116-Y120 WeakPolarHBondContact O-CD2 3.5Å; A116-Y120 PolarHBondContact O-N 2.95Å; A116-Y120 VanDerWaalsContact O-N 3.08Å; L117-Y120 PolarHBondContact O-N 3.5Å; Y120-N124 PolarHBondContact O-N 3.38Å; Y120-N124 VanDerWaalsContact O-N 3.14Å; Y120-L125 HydrophobicContact CD1-CD1 4.19Å; Y120-L125 HydrophobicContact CD1-CD2 4.02Å; Y120-L125 HydrophobicContact CD1-CG 4.4Å; Y120-L125 HydrophobicContact CG-CD1 4.43Å; Y120-A144 HydrophobicContact CD1-CB 4.37Å; Y120-A144 HydrophobicContact CE1-CB 3.7Å; Y120-T147 HydrophobicContact CE2-CG2 4.06Å; Y120-T147 VanDerWaalsContact OH-CB 3.24Å; Y120-T147 WeakPolarHBondContact OH-CB 3.29Å; Y120-T147 VanDerWaalsContact OH-CG2 3.25Å; Y120-T147 WeakPolarHBondContact OH-CG2 3.48Å; Y120-K148 HydrophobicContact CD2-CB 3.82Å; Y120-K148 HydrophobicContact CD2-CG 4.2Å; Y120-K148 HydrophobicContact CE2-CB 4.11Å; Y120-K148 HydrophobicContact CG-CB 4.33Å
121S87.8Confident88.2Confident85 Ų8557 Ų5759%0.59432%0.315SS*.Hα-helixtrans-69.8-36.4176.669.80000111.8L117 D118 N124L117-S121 WeakPolarHBondContact O-CB 3.47Å; L117-S121 PolarHBondContact O-N 2.89Å; L117-S121 PolarHBondContact O-OG 3.47Å; D118-S121 PolarHBondContact O-N 3.02Å; D118-S121 PolarHBondContact O-OG 2.86Å; S121-N124 PolarHBondContact O-N 2.97Å
122Q86.1Confident87.9Confident139 Ų13959.7 Ų59.765%0.6534%0.343SS*.Hα-helixtrans-66.1-37174.5-73.11711700113.3D118 H119D118-Q122 WeakPolarHBondContact O-CG 3.44Å; D118-Q122 PolarHBondContact O-N 3.48Å; H119-Q122 PolarHBondContact O-N 3.07Å
123V87.8Confident87.8Confident14 Ų1457.1 Ų57.19%0.08533%0.334CS..Hα-helixtrans-77.3-25.5179.1173.70000112.1Q97 S100 L101 H119 L125 L128Q97-V123 HydrophobicContact CB-CG1 4.2Å; Q97-V123 HydrophobicContact CG-CG1 4.17Å; S100-V123 VanDerWaalsContact CB-CG2 3.44Å; L101-V123 HydrophobicContact CD2-CB 4.4Å; L101-V123 HydrophobicContact CD2-CG1 4Å; L101-V123 HydrophobicContact CD2-CG2 4.44Å; L101-V123 HydrophobicContact CG-CG1 4.4Å; H119-V123 WeakPolarHBondContact O-CG2 3.48Å; H119-V123 PolarHBondContact O-N 3.39Å; H119-V123 VanDerWaalsContact O-N 3.16Å; V123-L125 HydrophobicContact CG1-CD2 4.47Å; V123-L128 HydrophobicContact CG1-CD1 4.24Å; V123-L128 HydrophobicContact CG1-CD2 4.08Å
124N86.9Confident87.7Confident70 Ų7056.7 Ų56.737%0.37434%0.337SS..THydrogen-bonded Turntrans48.284.6-170.6-165.714.5000112.9Y120 S121 D126 D127Y120-N124 PolarHBondContact O-N 3.38Å; Y120-N124 VanDerWaalsContact O-N 3.14Å; S121-N124 PolarHBondContact O-N 2.97Å; N124-D126 PolarHBondContact O-N 3.02Å; N124-D127 PolarHBondContact ND2-OD2 3.4Å; N124-D127 PolarHBondContact O-N 3.27Å
125L87.6Confident87.7Confident8 Ų854.5 Ų54.54%0.04232%0.32CS..G310 helixtrans-53.9-29.7-173.5-61.6-178.9000114.3L101 Y120 V123 D127 L128 A144 Y145 K148L101-L125 HydrophobicContact CD2-CD2 3.53Å; Y120-L125 HydrophobicContact CD1-CD1 4.19Å; Y120-L125 HydrophobicContact CD1-CD2 4.02Å; Y120-L125 HydrophobicContact CD1-CG 4.4Å; Y120-L125 HydrophobicContact CG-CD1 4.43Å; V123-L125 HydrophobicContact CG1-CD2 4.47Å; L125-D127 VanDerWaalsContact C-N 3.27Å; L125-D127 PolarHBondContact O-N 3.05Å; L125-L128 HydrophobicContact CD2-CD1 3.89Å; L125-L128 WeakPolarHBondContact O-CB 3.32Å; L125-L128 WeakPolarHBondContact O-CG 3.33Å; L125-L128 PolarHBondContact O-N 3.37Å; L125-A144 HydrophobicContact CD1-CB 4.41Å; L125-A144 HydrophobicContact CD2-CB 3.99Å; L125-Y145 HydrophobicContact CB-CD1 4.39Å; L125-Y145 HydrophobicContact CB-CE1 3.69Å; L125-Y145 HydrophobicContact CB-CE2 4.06Å; L125-Y145 HydrophobicContact CD1-CD1 3.77Å; L125-Y145 HydrophobicContact CD1-CE1 3.9Å; L125-Y145 HydrophobicContact CD1-CG 4.1Å; L125-Y145 HydrophobicContact CG-CE1 4.46Å; L125-Y145 PolarHBondContact O-OH 3.23Å; L125-Y145 VanDerWaalsContact O-OH 3.11Å; L125-K148 HydrophobicContact CD1-CB 4.3Å; L125-K148 HydrophobicContact CD1-CD 3.95Å
126D85.7Confident87.7Confident92 Ų9251.6 Ų51.649%0.49230%0.304SS..G310 helixtrans-71.2-20.1-177.1-71.6-8.8000113.5N124 Y145 K187N124-D126 PolarHBondContact O-N 3.02Å; D126-Y145 WeakPolarHBondContact CA-OH 3.31Å; D126-Y145 PolarHBondContact N-OH 3.3Å; D126-Y145 PolarHBondContact OD1-OH 2.99Å; D126-K187 IonicContact OD1-NZ 2.94Å; D126-K187 PolarHBondContact OD1-NZ 3.09Å; D126-K187 IonicContact OD2-NZ 2.79Å; D126-K187 PolarHBondContact OD2-NZ 3.03Å
127D86.2Confident87.8Confident117 Ų11752.9 Ų52.963%0.62631%0.309SS*.G310 helixtrans-87.2-6.5178.5-65.9-20.9000112.9N124 L125 Q129N124-D127 PolarHBondContact ND2-OD2 3.4Å; N124-D127 PolarHBondContact O-N 3.27Å; L125-D127 VanDerWaalsContact C-N 3.27Å; L125-D127 PolarHBondContact O-N 3.05Å; D127-Q129 PolarHBondContact O-N 2.68Å
128L87.3Confident87.9Confident10 Ų1051.4 Ų51.45%0.05230%0.301CS..  trans-71.7128.8-176.4-61.9178.2000111.6L101 V123 L125 L130 I141L101-L128 HydrophobicContact CD1-CD1 4.31Å; V123-L128 HydrophobicContact CG1-CD1 4.24Å; V123-L128 HydrophobicContact CG1-CD2 4.08Å; L125-L128 HydrophobicContact CD2-CD1 3.89Å; L125-L128 WeakPolarHBondContact O-CB 3.32Å; L125-L128 WeakPolarHBondContact O-CG 3.33Å; L125-L128 PolarHBondContact O-N 3.37Å; L128-L130 PolarHBondContact O-N 2.99Å; L128-I141 HydrophobicContact CB-CD1 4Å; L128-I141 HydrophobicContact CB-CG1 4.42Å; L128-I141 HydrophobicContact CD1-CD1 4.38Å; L128-I141 HydrophobicContact CD1-CG1 3.9Å; L128-I141 HydrophobicContact CD1-CG2 4.5Å
129Q86.3Confident88Confident146 Ų14648 Ų4868%0.68228%0.284SS*.  trans-76.2125.2-177.8-65.1-174.41.600112D127 A133D127-Q129 PolarHBondContact O-N 2.68Å; Q129-A133 WeakPolarHBondContact O-CB 3.34Å
130L89.1Confident88.1Confident10 Ų1046.7 Ų46.75%0.05228%0.278CS..  trans-95.3-26.6174.2-57.6177.8000113.1L128 L138 I141 I191 L316 R318L128-L130 PolarHBondContact O-N 2.99Å; L130-L138 HydrophobicContact CB-CD2 4.36Å; L130-L138 HydrophobicContact CD2-CD2 3.96Å; L130-I141 HydrophobicContact CD2-CD1 3.87Å; L130-I141 HydrophobicContact CD2-CG2 4.26Å; L130-I191 HydrophobicContact CD1-CD1 4.22Å; L130-I191 HydrophobicContact CD1-CG1 4.09Å; L130-I191 HydrophobicContact CD2-CD1 4.18Å; L130-I191 HydrophobicContact CD2-CG1 4.37Å; L130-I191 HydrophobicContact CD2-CG2 4.16Å; L130-L316 HydrophobicContact CD1-CB 4.26Å; L130-L316 HydrophobicContact CD1-CD2 4.24Å; L130-R318 HydrophobicContact CB-CB 4.09Å
131A84.6Confident88.3Confident60 Ų6046.6 Ų46.650%0.49628%0.278SS..THydrogen-bonded Turntrans-79.7127.3178.300000109.7A133A131-A133 PolarHBondContact O-N 3.17Å
132G79.9Confident88.6Confident80 Ų8042.5 Ų42.583%0.82525%0.249SC*.THydrogen-bonded Turntrans75-2-177.700000115.4
133A86.1Confident89Confident18 Ų1836.6 Ų36.615%0.14922%0.221CC..  trans-68.1143.6176.400000112.1Q129 A131 L138Q129-A133 WeakPolarHBondContact O-CB 3.34Å; A131-A133 PolarHBondContact O-N 3.17Å; A133-L138 HydrophobicContact CB-CD2 4.22Å
134P88.7Confident89.4Confident37 Ų3736 Ų3624%0.2422%0.218CC..  trans-66.8155173.129-34000111Y136 R137 L138P134-Y136 HydrophobicContact CB-CD1 3.83Å; P134-Y136 HydrophobicContact CB-CE1 3.58Å; P134-Y136 HydrophobicContact CG-CD1 3.95Å; P134-Y136 HydrophobicContact CG-CE1 3.31Å; P134-Y136 PolarHBondContact O-N 3.16Å; P134-R137 HydrophobicContact CG-CB 3.9Å; P134-R137 WeakPolarHBondContact O-CB 3.49Å; P134-R137 PolarHBondContact O-N 2.82Å; P134-L138 PolarHBondContact O-N 3.38Å
135V89.3Confident89.8Confident24 Ų2433.2 Ų33.215%0.14520%0.202CC..Hα-helixtrans-57.9-44.6-171.7175.30000112.2R137 L138 S139 Y195 E198 A199V135-R137 PolarHBondContact O-N 3.38Å; V135-L138 WeakPolarHBondContact O-CB 3.35Å; V135-L138 PolarHBondContact O-N 2.99Å; V135-S139 PolarHBondContact O-N 3.3Å; V135-Y195 HydrophobicContact CG1-CD2 3.76Å; V135-Y195 HydrophobicContact CG1-CE2 3.73Å; V135-Y195 WeakPolarHBondContact O-CD2 3.38Å; V135-E198 HydrophobicContact CG2-CB 4.29Å; V135-A199 HydrophobicContact CG1-CB 3.81Å
136Y89.8Confident90.2Very high11 Ų1132.8 Ų32.84%0.04320%0.2CC..Hα-helixtrans-57.7-34.4177.477.6-96.1000112.7E15 R18 S19 E98 P134 S139 M140E15-Y136 HydrophobicContact CB-CE1 4.22Å; E15-Y136 HydrophobicContact CG-CE1 4Å; R18-Y136 HydrophobicContact CB-CD1 4.07Å; R18-Y136 HydrophobicContact CB-CD2 4.47Å; R18-Y136 HydrophobicContact CB-CG 3.87Å; R18-Y136 VanDerWaalsContact CZ-CD2 3.49Å; R18-Y136 PolarHBondContact NH1-OH 3.11Å; R18-Y136 VanDerWaalsContact NH2-CE2 3.29Å; S19-Y136 PolarHBondContact OG-N 3.35Å; E98-Y136 WeakPolarHBondContact OE1-CE2 3.47Å; E98-Y136 PolarHBondContact OE1-OH 2.88Å; P134-Y136 HydrophobicContact CB-CD1 3.83Å; P134-Y136 HydrophobicContact CB-CE1 3.58Å; P134-Y136 HydrophobicContact CG-CD1 3.95Å; P134-Y136 HydrophobicContact CG-CE1 3.31Å; P134-Y136 PolarHBondContact O-N 3.16Å; Y136-S139 WeakPolarHBondContact O-CB 3.4Å; Y136-S139 PolarHBondContact O-N 2.9Å; Y136-M140 HydrophobicContact CD2-SD 3.93Å; Y136-M140 HydrophobicContact CE2-SD 4.08Å; Y136-M140 WeakPolarHBondContact O-CG 3.3Å; Y136-M140 PolarHBondContact O-N 3.46Å
137R92.1Very high90.6Very high28 Ų2828.4 Ų28.411%0.10618%0.177CC..Hα-helixtrans-72.8-33.1-177.6-169.8165.6-174.2174.7-3.6111.7D94 P134 V135 S139 M140 I141D94-R137 VanDerWaalsContact CB-NH1 3.27Å; D94-R137 IonicContact OD1-CZ 3.06Å; D94-R137 VanDerWaalsContact OD1-CZ 3.28Å; D94-R137 IonicContact OD1-NH1 3.68Å; D94-R137 PolarHBondContact OD1-NH1 3.45Å; D94-R137 IonicContact OD1-NH2 2.91Å; D94-R137 PolarHBondContact OD1-NH2 2.96Å; D94-R137 IonicContact OD2-NH1 3.64Å; P134-R137 HydrophobicContact CG-CB 3.9Å; P134-R137 WeakPolarHBondContact O-CB 3.49Å; P134-R137 PolarHBondContact O-N 2.82Å; V135-R137 PolarHBondContact O-N 3.38Å; R137-S139 VanDerWaalsContact C-N 3.32Å; R137-M140 PolarHBondContact O-N 3.27Å; R137-I141 HydrophobicContact CG-CD1 4.14Å; R137-I141 WeakPolarHBondContact O-CG1 3.38Å; R137-I141 PolarHBondContact O-N 2.98Å
138L92.6Very high90.9Very high1 Ų125.1 Ų25.11%0.00516%0.157CC..Hα-helixtrans-60.9-42.9170.8-61.7174.3000111.1L130 A133 P134 V135 I141 A142 I191 L194L130-L138 HydrophobicContact CB-CD2 4.36Å; L130-L138 HydrophobicContact CD2-CD2 3.96Å; A133-L138 HydrophobicContact CB-CD2 4.22Å; P134-L138 PolarHBondContact O-N 3.38Å; V135-L138 WeakPolarHBondContact O-CB 3.35Å; V135-L138 PolarHBondContact O-N 2.99Å; L138-I141 PolarHBondContact O-N 2.88Å; L138-A142 WeakPolarHBondContact O-CB 3.43Å; L138-A142 PolarHBondContact O-N 3.21Å; L138-I191 WeakPolarHBondContact O-CG2 3.46Å; L138-L194 HydrophobicContact CD1-CD2 4.36Å; L138-L194 HydrophobicContact CD1-CG 4.25Å; L138-L194 HydrophobicContact CD2-CD2 4.15Å
139S92.8Very high91.2Very high15 Ų1524.7 Ų24.711%0.10516%0.155CC..Hα-helixtrans-60.2-48.9173.7-170.40000111.3V135 Y136 R137 I141 A142 E143V135-S139 PolarHBondContact O-N 3.3Å; Y136-S139 WeakPolarHBondContact O-CB 3.4Å; Y136-S139 PolarHBondContact O-N 2.9Å; R137-S139 VanDerWaalsContact C-N 3.32Å; S139-I141 VanDerWaalsContact C-N 3.31Å; S139-I141 PolarHBondContact O-N 3.14Å; S139-A142 PolarHBondContact O-N 3.38Å; S139-E143 VanDerWaalsContact O-CG 3.28Å; S139-E143 WeakPolarHBondContact O-CG 3.37Å; S139-E143 PolarHBondContact O-N 3.05Å
140M93.1Very high91.5Very high11 Ų1118.1 Ų18.15%0.05412%0.124CC..Hα-helixtrans-58.1-42.1179.2-71.2-177.36700112.7E98 L101 L102 Y136 R137 A144E98-M140 HydrophobicContact CB-CE 3.78Å; E98-M140 HydrophobicContact CG-CE 3.87Å; E98-M140 HydrophobicContact CG-SD 4.07Å; L101-M140 HydrophobicContact CB-CE 4.32Å; L101-M140 HydrophobicContact CD1-CE 4.49Å; L102-M140 HydrophobicContact CD1-CE 4.32Å; L102-M140 HydrophobicContact CD2-CE 4.15Å; L102-M140 HydrophobicContact CG-CE 3.9Å; Y136-M140 HydrophobicContact CD2-SD 3.93Å; Y136-M140 HydrophobicContact CE2-SD 4.08Å; Y136-M140 WeakPolarHBondContact O-CG 3.3Å; Y136-M140 PolarHBondContact O-N 3.46Å; R137-M140 PolarHBondContact O-N 3.27Å; M140-A144 VanDerWaalsContact O-CB 3.26Å; M140-A144 WeakPolarHBondContact O-CB 3.39Å; M140-A144 PolarHBondContact O-N 3.05Å
141I94.5Very high91.6Very high2 Ų217.7 Ų17.71%0.0112%0.122CC..Hα-helixtrans-66.8-44.9178.4-64.7166.3000110.4L128 L130 R137 L138 S139 E143 A144 Y145 I191L128-I141 HydrophobicContact CB-CD1 4Å; L128-I141 HydrophobicContact CB-CG1 4.42Å; L128-I141 HydrophobicContact CD1-CD1 4.38Å; L128-I141 HydrophobicContact CD1-CG1 3.9Å; L128-I141 HydrophobicContact CD1-CG2 4.5Å; L130-I141 HydrophobicContact CD2-CD1 3.87Å; L130-I141 HydrophobicContact CD2-CG2 4.26Å; R137-I141 HydrophobicContact CG-CD1 4.14Å; R137-I141 WeakPolarHBondContact O-CG1 3.38Å; R137-I141 PolarHBondContact O-N 2.98Å; L138-I141 PolarHBondContact O-N 2.88Å; S139-I141 VanDerWaalsContact C-N 3.31Å; S139-I141 PolarHBondContact O-N 3.14Å; I141-E143 PolarHBondContact O-N 3.29Å; I141-A144 PolarHBondContact O-N 2.85Å; I141-Y145 HydrophobicContact CG2-CD2 3.88Å; I141-Y145 HydrophobicContact CG2-CE2 3.74Å; I141-Y145 WeakPolarHBondContact O-CD2 3.21Å; I141-Y145 PolarHBondContact O-N 3.39Å; I141-Y145 VanDerWaalsContact O-N 3.07Å; I141-I191 HydrophobicContact CG2-CD1 3.82Å; I141-I191 HydrophobicContact CG2-CG2 4.43Å
142A94.8Very high91.8Very high0 Ų015.6 Ų15.60%010%0.102CC..Hα-helixtrans-59.4-46.7177.200000111.7L138 S139 Y145 A146 S188 I191 A192 L227L138-A142 WeakPolarHBondContact O-CB 3.43Å; L138-A142 PolarHBondContact O-N 3.21Å; S139-A142 PolarHBondContact O-N 3.38Å; A142-Y145 PolarHBondContact O-N 3.27Å; A142-A146 PolarHBondContact O-N 3.37Å; A142-A146 VanDerWaalsContact O-N 3.11Å; A142-S188 WeakPolarHBondContact O-CB 3.4Å; A142-S188 PolarHBondContact O-OG 2.82Å; A142-I191 HydrophobicContact CB-CB 4.15Å; A142-I191 HydrophobicContact CB-CG2 3.97Å; A142-A192 HydrophobicContact CB-CB 4.11Å; A142-L227 HydrophobicContact CB-CD2 3.77Å
143E94.8Very high92.2Very high14 Ų1414.5 Ų14.57%0.0658%0.076CC..Hα-helixtrans-64.2-40.2176.7-66.2178.2135.600111.8K105 S139 I141 Y145 A146 T147 F226 L227K105-E143 VanDerWaalsContact NZ-CD 3.34Å; K105-E143 IonicContact NZ-OE1 3.62Å; K105-E143 IonicContact NZ-OE2 3.56Å; K105-E143 PolarHBondContact NZ-OE2 3.11Å; S139-E143 VanDerWaalsContact O-CG 3.28Å; S139-E143 WeakPolarHBondContact O-CG 3.37Å; S139-E143 PolarHBondContact O-N 3.05Å; I141-E143 PolarHBondContact O-N 3.29Å; E143-Y145 PolarHBondContact O-N 3.37Å; E143-A146 PolarHBondContact O-N 3.5Å; E143-T147 WeakPolarHBondContact O-CB 3.41Å; E143-T147 PolarHBondContact O-N 3.17Å; E143-T147 PolarHBondContact O-OG1 3.33Å; E143-F226 HydrophobicContact CB-CB 4.06Å; E143-F226 HydrophobicContact CG-CB 3.88Å; E143-L227 HydrophobicContact CG-CD2 3.85Å; E143-L227 HydrophobicContact CG-CG 4.06Å
144A95.1Very high92.2Very high2 Ų218.3 Ų18.32%0.0179%0.09CC..Hα-helixtrans-59.6-44.1177.200000112.2L101 Y120 L125 M140 I141 T147 K148L101-A144 HydrophobicContact CD1-CB 4.46Å; L101-A144 HydrophobicContact CD2-CB 3.86Å; Y120-A144 HydrophobicContact CD1-CB 4.37Å; Y120-A144 HydrophobicContact CE1-CB 3.7Å; L125-A144 HydrophobicContact CD1-CB 4.41Å; L125-A144 HydrophobicContact CD2-CB 3.99Å; M140-A144 VanDerWaalsContact O-CB 3.26Å; M140-A144 WeakPolarHBondContact O-CB 3.39Å; M140-A144 PolarHBondContact O-N 3.05Å; I141-A144 PolarHBondContact O-N 2.85Å; A144-T147 PolarHBondContact O-N 3.11Å; A144-K148 WeakPolarHBondContact O-CB 3.35Å; A144-K148 PolarHBondContact O-N 2.93Å
145Y95.9Very high91.9Very high11 Ų1118.6 Ų18.64%0.0439%0.089CC..Hα-helixtrans-64.8-40.7174.3-82.9-69.7000112.5L125 D126 I141 A142 E143 K148 G149 K187 I191L125-Y145 HydrophobicContact CB-CD1 4.39Å; L125-Y145 HydrophobicContact CB-CE1 3.69Å; L125-Y145 HydrophobicContact CB-CE2 4.06Å; L125-Y145 HydrophobicContact CD1-CD1 3.77Å; L125-Y145 HydrophobicContact CD1-CE1 3.9Å; L125-Y145 HydrophobicContact CD1-CG 4.1Å; L125-Y145 HydrophobicContact CG-CE1 4.46Å; L125-Y145 PolarHBondContact O-OH 3.23Å; L125-Y145 VanDerWaalsContact O-OH 3.11Å; D126-Y145 WeakPolarHBondContact CA-OH 3.31Å; D126-Y145 PolarHBondContact N-OH 3.3Å; D126-Y145 PolarHBondContact OD1-OH 2.99Å; I141-Y145 HydrophobicContact CG2-CD2 3.88Å; I141-Y145 HydrophobicContact CG2-CE2 3.74Å; I141-Y145 WeakPolarHBondContact O-CD2 3.21Å; I141-Y145 PolarHBondContact O-N 3.39Å; I141-Y145 VanDerWaalsContact O-N 3.07Å; A142-Y145 PolarHBondContact O-N 3.27Å; E143-Y145 PolarHBondContact O-N 3.37Å; Y145-K148 PolarHBondContact O-N 3.47Å; Y145-G149 PolarHBondContact O-N 3.18Å; Y145-K187 HydrophobicContact CD1-CB 4.17Å; Y145-K187 HydrophobicContact CD1-CD 4.27Å; Y145-K187 HydrophobicContact CD2-CB 4.31Å; Y145-K187 HydrophobicContact CE1-CB 4.28Å; Y145-K187 HydrophobicContact CE1-CD 3.62Å; Y145-K187 HydrophobicContact CE2-CB 4.4Å; Y145-K187 HydrophobicContact CG-CB 4.19Å; Y145-I191 HydrophobicContact CD2-CD1 3.9Å; Y145-I191 HydrophobicContact CE2-CD1 3.78Å
146A95.1Very high91Very high0 Ų022.7 Ų22.70%012%0.117CC..Hα-helixtrans-62-46.4175.400000111.4A142 E143 G149 L150 S188 F226A142-A146 PolarHBondContact O-N 3.37Å; A142-A146 VanDerWaalsContact O-N 3.11Å; E143-A146 PolarHBondContact O-N 3.5Å; A146-G149 PolarHBondContact O-N 3.28Å; A146-L150 WeakPolarHBondContact O-CG 3.47Å; A146-L150 PolarHBondContact O-N 2.97Å; A146-S188 WeakPolarHBondContact CB-OG 3.47Å; A146-F226 HydrophobicContact CB-CB 4.42Å; A146-F226 VanDerWaalsContact CB-O 3.25Å; A146-F226 WeakPolarHBondContact CB-O 3.4Å
147T94.3Very high89.6Confident0 Ų026.5 Ų26.50%014%0.138CC..Hα-helixtrans-65.8-39.7178.1-54.90000111.6Y108 Y120 E143 A144 G149 L150 C151 F226Y108-T147 VanDerWaalsContact CB-CG2 3.49Å; Y108-T147 HydrophobicContact CD1-CG2 4.08Å; Y108-T147 HydrophobicContact CD2-CG2 4.12Å; Y108-T147 HydrophobicContact CG-CG2 3.62Å; Y120-T147 HydrophobicContact CE2-CG2 4.06Å; Y120-T147 VanDerWaalsContact OH-CB 3.24Å; Y120-T147 WeakPolarHBondContact OH-CB 3.29Å; Y120-T147 VanDerWaalsContact OH-CG2 3.25Å; Y120-T147 WeakPolarHBondContact OH-CG2 3.48Å; E143-T147 WeakPolarHBondContact O-CB 3.41Å; E143-T147 PolarHBondContact O-N 3.17Å; E143-T147 PolarHBondContact O-OG1 3.33Å; A144-T147 PolarHBondContact O-N 3.11Å; T147-G149 VanDerWaalsContact C-N 3.34Å; T147-G149 PolarHBondContact O-N 3.5Å; T147-L150 PolarHBondContact O-N 3.3Å; T147-C151 PolarHBondContact O-N 2.82Å; T147-C151 PolarHBondContact O-SG 3.24Å; T147-F226 VanDerWaalsContact OG1-CD1 3.31Å; T147-F226 WeakPolarHBondContact OG1-CD1 3.38Å; T147-F226 WeakPolarHBondContact OG1-CE1 3.3Å
148K94.1Very high87.5Confident48 Ų4830.9 Ų30.921%0.20917%0.173CC..Hα-helixtrans-57.8-47.3172.5-175.8-175.5171.4-1670110.7L117 Y120 L125 A144 Y145 L150 C151 L152 E180L117-K148 HydrophobicContact CD2-CG 3.89Å; Y120-K148 HydrophobicContact CD2-CB 3.82Å; Y120-K148 HydrophobicContact CD2-CG 4.2Å; Y120-K148 HydrophobicContact CE2-CB 4.11Å; Y120-K148 HydrophobicContact CG-CB 4.33Å; L125-K148 HydrophobicContact CD1-CB 4.3Å; L125-K148 HydrophobicContact CD1-CD 3.95Å; A144-K148 WeakPolarHBondContact O-CB 3.35Å; A144-K148 PolarHBondContact O-N 2.93Å; Y145-K148 PolarHBondContact O-N 3.47Å; K148-L150 PolarHBondContact O-N 2.97Å; K148-C151 PolarHBondContact O-N 3.5Å; K148-L152 HydrophobicContact CG-CD1 4.32Å; K148-L152 WeakPolarHBondContact O-CG 3.45Å; K148-L152 PolarHBondContact O-N 3.37Å; K148-E180 WeakPolarHBondContact CE-OE1 3.37Å; K148-E180 IonicContact NZ-OE1 3.01Å; K148-E180 PolarHBondContact NZ-OE1 3.24Å
149G92.3Very high85Confident0 Ų034.9 Ų34.90%020%0.201CC..Hα-helixtrans-58.4-45.3175.300000112.6Y145 A146 T147 L152 E153 Y185Y145-G149 PolarHBondContact O-N 3.18Å; A146-G149 PolarHBondContact O-N 3.28Å; T147-G149 VanDerWaalsContact C-N 3.34Å; T147-G149 PolarHBondContact O-N 3.5Å; G149-L152 PolarHBondContact O-N 3.21Å; G149-E153 PolarHBondContact O-N 3.49Å; G149-Y185 VanDerWaalsContact C-OH 3.32Å
150L91.9Very high82.5Confident9 Ų940.1 Ų40.15%0.04723%0.234CC..Hα-helixtrans-63.3-43.5177.3-73.3164.6000112.6Y108 A146 T147 K148 L152 E153 Q154 Y185 Y225 F226 T229Y108-L150 HydrophobicContact CD2-CB 4.37Å; Y108-L150 HydrophobicContact CE1-CD1 4.36Å; Y108-L150 HydrophobicContact CE2-CB 3.61Å; Y108-L150 HydrophobicContact CE2-CD1 4.38Å; A146-L150 WeakPolarHBondContact O-CG 3.47Å; A146-L150 PolarHBondContact O-N 2.97Å; T147-L150 PolarHBondContact O-N 3.3Å; K148-L150 PolarHBondContact O-N 2.97Å; L150-L152 VanDerWaalsContact C-N 3.33Å; L150-L152 PolarHBondContact O-N 3.4Å; L150-E153 PolarHBondContact O-N 3.18Å; L150-Q154 WeakPolarHBondContact O-CG 3.35Å; L150-Q154 PolarHBondContact O-N 2.88Å; L150-Y185 HydrophobicContact CG-CE1 4.35Å; L150-Y185 PolarHBondContact N-OH 3.38Å; L150-Y225 HydrophobicContact CD1-CE1 4Å; L150-F226 HydrophobicContact CD1-CD1 4.1Å; L150-F226 HydrophobicContact CD1-CE1 4.25Å; L150-T229 HydrophobicContact CD1-CG2 4.12Å; L150-T229 HydrophobicContact CD2-CG2 4.04Å; L150-T229 HydrophobicContact CG-CG2 4.16Å
151C91.7Very high79.8Confident0 Ų043.1 Ų43.10%026%0.257CS..Hα-helixtrans-61.4-42.3175.3-690000111.6Y108 L117 T147 K148 E153 Q154 I155Y108-C151 VanDerWaalsContact CD2-SG 3.59Å; L117-C151 HydrophobicContact CD1-CB 4.44Å; L117-C151 HydrophobicContact CD2-CB 3.75Å; L117-C151 HydrophobicContact CG-CB 3.89Å; T147-C151 PolarHBondContact O-N 2.82Å; T147-C151 PolarHBondContact O-SG 3.24Å; K148-C151 PolarHBondContact O-N 3.5Å; C151-E153 VanDerWaalsContact C-N 3.28Å; C151-E153 PolarHBondContact O-N 3.49Å; C151-Q154 PolarHBondContact O-N 2.97Å; C151-Q154 VanDerWaalsContact O-N 3.17Å; C151-I155 PolarHBondContact O-N 3.38Å
152L90.1Very high77.2Confident16 Ų1651.5 Ų51.58%0.08430%0.301CS..Hα-helixtrans-64.2-30.8177.2-73.8173.2000112.5L117 K148 G149 L150 R177 E180 I181L117-L152 HydrophobicContact CD1-CD2 3.8Å; L117-L152 HydrophobicContact CD1-CG 4.41Å; L117-L152 HydrophobicContact CD2-CD2 4.11Å; L117-L152 HydrophobicContact CD2-CG 4Å; K148-L152 HydrophobicContact CG-CD1 4.32Å; K148-L152 WeakPolarHBondContact O-CG 3.45Å; K148-L152 PolarHBondContact O-N 3.37Å; G149-L152 PolarHBondContact O-N 3.21Å; L150-L152 VanDerWaalsContact C-N 3.33Å; L150-L152 PolarHBondContact O-N 3.4Å; L152-R177 PolarHBondContact O-NE 3.08Å; L152-R177 PolarHBondContact O-NH2 3.33Å; L152-E180 HydrophobicContact CD1-CG 4.08Å; L152-I181 HydrophobicContact CB-CD1 4.07Å; L152-I181 HydrophobicContact CB-CG1 3.57Å; L152-I181 HydrophobicContact CD1-CG1 4.18Å
153E88.5Confident74.3Confident58 Ų5855.4 Ų55.427%0.27133%0.328SS..Hα-helixtrans-70.5-29.4173.4-73.9-174.4-166.200113.3G149 L150 C151 I181 Y185 R233G149-E153 PolarHBondContact O-N 3.49Å; L150-E153 PolarHBondContact O-N 3.18Å; C151-E153 VanDerWaalsContact C-N 3.28Å; C151-E153 PolarHBondContact O-N 3.49Å; E153-I181 HydrophobicContact CG-CD1 4.19Å; E153-I181 HydrophobicContact CG-CG2 3.88Å; E153-Y185 WeakPolarHBondContact OE1-CE2 3.43Å; E153-Y185 PolarHBondContact OE1-OH 3.4Å; E153-R233 IonicContact OE1-CZ 3.81Å; E153-R233 IonicContact OE1-NE 3.34Å; E153-R233 PolarHBondContact OE1-NE 2.95Å; E153-R233 IonicContact OE1-NH2 3.24Å; E153-R233 PolarHBondContact OE1-NH2 3.27Å; E153-R233 IonicContact OE2-CZ 3.12Å; E153-R233 IonicContact OE2-NE 3.21Å; E153-R233 IonicContact OE2-NH2 3.47Å; E153-R233 PolarHBondContact OE2-NH2 3.35Å
154Q85.5Confident71.5Confident97 Ų9763.1 Ų63.145%0.45337%0.369SS..Hα-helixtrans-85.6-23.8-173-66.2-61.5-44.300114.2Y113 L150 C151Y113-Q154 HydrophobicContact CD1-CB 4.3Å; Y113-Q154 HydrophobicContact CD1-CG 4.4Å; Y113-Q154 HydrophobicContact CD2-CB 3.58Å; Y113-Q154 HydrophobicContact CD2-CG 4.33Å; Y113-Q154 HydrophobicContact CE1-CB 4.31Å; Y113-Q154 HydrophobicContact CE1-CG 4.05Å; Y113-Q154 HydrophobicContact CE2-CB 3.57Å; Y113-Q154 HydrophobicContact CE2-CG 3.95Å; Y113-Q154 HydrophobicContact CG-CB 3.94Å; L150-Q154 WeakPolarHBondContact O-CG 3.35Å; L150-Q154 PolarHBondContact O-N 2.88Å; C151-Q154 PolarHBondContact O-N 2.97Å; C151-Q154 VanDerWaalsContact O-N 3.17Å
155I81.3Confident68.4Low43 Ų4366.9 Ų66.922%0.22140%0.396CS..SBendtrans-85.5126.8-179.3-64.7164.6000108.8L117 C151 R177L117-I155 HydrophobicContact CD1-CD1 3.42Å; L117-I155 VanDerWaalsContact CD1-CD1 3.42Å; L117-I155 HydrophobicContact CG-CD1 4.42Å; C151-I155 PolarHBondContact O-N 3.38Å; I155-R177 VanDerWaalsContact CB-NH2 3.34Å; I155-R177 PolarHBondContact O-NH1 2.93Å; I155-R177 PolarHBondContact O-NH2 3.44Å
156P70.8Confident65.4Low111 Ų11170.8 Ų70.872%0.72144%0.44SS*.PPolyproline II helixtrans-67.3150.7176.624.6-30.8000111.9S158 R177P156-S158 PolarHBondContact O-N 3.32Å; P156-R177 PolarHBondContact O-NH1 3.09Å
157D61Low62.2Low90 Ų9074.2 Ų74.248%0.48146%0.463SS..PPolyproline II helixtrans-65.2130.8172.5-84.8-25.4000110.5S159 R177D157-S159 PolarHBondContact O-N 3.08Å; D157-R177 WeakPolarHBondContact OD1-CD 3.3Å; D157-R177 IonicContact OD1-CZ 3.47Å; D157-R177 IonicContact OD1-NE 3.91Å; D157-R177 IonicContact OD1-NH1 3.84Å; D157-R177 PolarHBondContact OD1-NH1 3.47Å
158S47.7Very low59.4Low121 Ų12180.4 Ų80.485%0.84650%0.504SS*.SBendtrans-70.86.5176.348.10000114.1P156P156-S158 PolarHBondContact O-N 3.32Å
159S40.7Very low56.5Low85 Ų8582.6 Ų82.659%0.59453%0.525SS*.  trans-122.3103.7-177.9-49.80000109.9D157 S161D157-S159 PolarHBondContact O-N 3.08Å; S159-S161 VanDerWaalsContact C-N 3.31Å; S159-S161 PolarHBondContact O-N 3.04Å
160P40.2Very low54Low124 Ų12487.1 Ų87.181%0.80555%0.553SS**  trans-73.892.1169.530.7-28.8000107.4L162P160-L162 PolarHBondContact O-N 3.46Å
161S35.7Very low52Low75 Ų7591.7 Ų91.752%0.52458%0.577SS.*  trans-69111.8157.751.70000106.8S159 S163 R172S159-S161 VanDerWaalsContact C-N 3.31Å; S159-S161 PolarHBondContact O-N 3.04Å; S161-S163 PolarHBondContact O-N 3Å; S161-R172 PolarHBondContact OG-NH2 3.26Å
162L39.6Very low50.2Low178 Ų17898.2 Ų98.293%0.93260%0.602SS**SBendtrans-54.596.1174.6-84.4139.2000110.2P160P160-L162 PolarHBondContact O-N 3.46Å
163S33.4Very low48.5Very low82 Ų82101.4 Ų101.457%0.57363%0.626SS**  trans-146.175.9152.764.50000108.2S161 S165S161-S163 PolarHBondContact O-N 3Å; S163-S165 VanDerWaalsContact C-N 3.28Å; S163-S165 PolarHBondContact O-N 3.38Å; S163-S165 VanDerWaalsContact O-N 3.1Å
164N36.4Very low47.1Very low175 Ų175100.9 Ų100.994%0.93663%0.627SS**  trans-75.186.8165-15218.3000107.2
165S31.1Very low46.5Very low81 Ų8197.4 Ų97.457%0.56661%0.613SS**  trans-136.8112.4159.356.20000108.7S163 S167S163-S165 VanDerWaalsContact C-N 3.28Å; S163-S165 PolarHBondContact O-N 3.38Å; S163-S165 VanDerWaalsContact O-N 3.1Å; S165-S167 PolarHBondContact O-N 3.44Å
166G31.1Very low46.3Very low94 Ų94101 Ų10197%0.96964%0.639SS**  trans-69.470.3174.600000112
167S30Very low46.8Very low71 Ų7197.9 Ų97.950%0.49761%0.613SS.*SBendtrans-144.3129.9169.851.20000108.7S165 S169S165-S167 PolarHBondContact O-N 3.44Å; S167-S169 VanDerWaalsContact C-N 3.31Å; S167-S169 PolarHBondContact O-N 2.92Å
168P34.5Very low47.8Very low131 Ų13196.8 Ų96.885%0.85161%0.605SS**  trans-70.988.9176.929.7-31.1000108.5T170P168-T170 PolarHBondContact O-N 2.97Å
169S33.6Very low49.6Very low94 Ų9492.7 Ų92.766%0.65757%0.572SS**  trans-77.2112.2169.657.90000108.1S167 N171S167-S169 VanDerWaalsContact C-N 3.31Å; S167-S169 PolarHBondContact O-N 2.92Å; S169-N171 PolarHBondContact O-N 3.22Å
170T40.2Very low51.8Low94 Ų9492.5 Ų92.558%0.57756%0.562SS**SBendtrans-658.8179.348.60000114.4P168P168-T170 PolarHBondContact O-N 2.97Å
171N49.5Very low54.2Low105 Ų10587.2 Ų87.256%0.56153%0.527SS*.  trans-138.674.6-155.7-63.4-12.8000111.6S169S169-N171 PolarHBondContact O-N 3.22Å
172R53.3Low56.8Low137 Ų13783.7 Ų83.752%0.51750%0.502SS..  trans-132.4137.2169.4-159-179.5-175.2179.53.5109.8S161S161-R172 PolarHBondContact OG-NH2 3.26Å
173S54.5Low59.3Low84 Ų8476.3 Ų76.359%0.58747%0.465SS*.PPolyproline II helixtrans-61.6141.5167.347.70000109.4T175S173-T175 PolarHBondContact O-N 3.05Å
174P59.6Low62.1Low46 Ų4672.6 Ų72.630%0.29944%0.439SS..PPolyproline II helixtrans-62.1130.6-177.123.4-30.8000109.6E178P174-E178 VanDerWaalsContact CA-OE2 3.24Å; P174-E178 WeakPolarHBondContact CA-OE2 3.47Å; P174-E178 HydrophobicContact CB-CB 4.03Å
175T72.8Confident64.9Low25 Ų2564.3 Ų64.315%0.15339%0.394CS..PPolyproline II helixtrans-59.4155.5170.365.80000109.5S173 R177 E178 Q179S173-T175 PolarHBondContact O-N 3.05Å; T175-R177 PolarHBondContact O-N 3Å; T175-E178 PolarHBondContact N-OE2 2.98Å; T175-E178 PolarHBondContact O-N 3.32Å; T175-E178 WeakPolarHBondContact OG1-CB 3.01Å; T175-E178 VanDerWaalsContact OG1-CG 3.28Å; T175-E178 WeakPolarHBondContact OG1-CG 3.15Å; T175-E178 PolarHBondContact OG1-N 2.66Å; T175-E178 VanDerWaalsContact OG1-N 3.13Å; T175-Q179 PolarHBondContact O-N 3.19Å
176P75.8Confident67.9Low119 Ų11961.3 Ų61.377%0.77337%0.371SS*.Hα-helixtrans-53.9-32.2177.619.8-32.6000112.4E180P176-E180 PolarHBondContact O-N 3.21Å; P176-E180 VanDerWaalsContact O-N 3.09Å
177R82.4Confident70.9Confident45 Ų4557.8 Ų57.817%0.1733%0.329CS..Hα-helixtrans-70.4-44.7173.9-172.5-179.4-179.6174.9-1113.1L152 I155 P156 D157 T175 Q179 E180 I181L152-R177 PolarHBondContact O-NE 3.08Å; L152-R177 PolarHBondContact O-NH2 3.33Å; I155-R177 VanDerWaalsContact CB-NH2 3.34Å; I155-R177 PolarHBondContact O-NH1 2.93Å; I155-R177 PolarHBondContact O-NH2 3.44Å; P156-R177 PolarHBondContact O-NH1 3.09Å; D157-R177 WeakPolarHBondContact OD1-CD 3.3Å; D157-R177 IonicContact OD1-CZ 3.47Å; D157-R177 IonicContact OD1-NE 3.91Å; D157-R177 IonicContact OD1-NH1 3.84Å; D157-R177 PolarHBondContact OD1-NH1 3.47Å; T175-R177 PolarHBondContact O-N 3Å; R177-Q179 VanDerWaalsContact C-N 3.25Å; R177-Q179 PolarHBondContact O-N 2.95Å; R177-E180 WeakPolarHBondContact O-CB 3.48Å; R177-E180 PolarHBondContact O-N 2.98Å; R177-E180 VanDerWaalsContact O-N 3.11Å; R177-I181 HydrophobicContact CG-CD1 4.3Å; R177-I181 WeakPolarHBondContact O-CG1 3.37Å; R177-I181 PolarHBondContact O-N 3.39Å
178E81.9Confident74Confident67 Ų6754.4 Ų54.431%0.31331%0.306SS..Hα-helixtrans-60.2-37.7174-76.8168.9169.300111.7P174 T175 E180 I181 I182P174-E178 VanDerWaalsContact CA-OE2 3.24Å; P174-E178 WeakPolarHBondContact CA-OE2 3.47Å; P174-E178 HydrophobicContact CB-CB 4.03Å; T175-E178 PolarHBondContact N-OE2 2.98Å; T175-E178 PolarHBondContact O-N 3.32Å; T175-E178 WeakPolarHBondContact OG1-CB 3.01Å; T175-E178 VanDerWaalsContact OG1-CG 3.28Å; T175-E178 WeakPolarHBondContact OG1-CG 3.15Å; T175-E178 PolarHBondContact OG1-N 2.66Å; T175-E178 VanDerWaalsContact OG1-N 3.13Å; E178-E180 VanDerWaalsContact C-N 3.35Å; E178-I181 WeakPolarHBondContact O-CB 3.44Å; E178-I181 PolarHBondContact O-N 3.34Å; E178-I182 VanDerWaalsContact O-CG1 3.25Å; E178-I182 WeakPolarHBondContact O-CG1 3.43Å; E178-I182 PolarHBondContact O-N 2.98Å
179Q84.6Confident76.8Confident34 Ų3448.2 Ų48.216%0.15927%0.265CS..Hα-helixtrans-65.9-36.5174.1-173.960.263.600112.1T175 R177 T183 N313T175-Q179 PolarHBondContact O-N 3.19Å; R177-Q179 VanDerWaalsContact C-N 3.25Å; R177-Q179 PolarHBondContact O-N 2.95Å; Q179-T183 WeakPolarHBondContact O-CB 3.3Å; Q179-T183 PolarHBondContact O-N 2.75Å; Q179-T183 PolarHBondContact O-OG1 3.44Å; Q179-N313 PolarHBondContact NE2-ND2 2.6Å
180E87.7Confident79.8Confident81 Ų8144.2 Ų44.238%0.37924%0.237SC..Hα-helixtrans-64.2-44.3171.8-171.6-177179.200111.5K148 L152 P176 R177 E178 I182 T183 C184K148-E180 WeakPolarHBondContact CE-OE1 3.37Å; K148-E180 IonicContact NZ-OE1 3.01Å; K148-E180 PolarHBondContact NZ-OE1 3.24Å; L152-E180 HydrophobicContact CD1-CG 4.08Å; P176-E180 PolarHBondContact O-N 3.21Å; P176-E180 VanDerWaalsContact O-N 3.09Å; R177-E180 WeakPolarHBondContact O-CB 3.48Å; R177-E180 PolarHBondContact O-N 2.98Å; R177-E180 VanDerWaalsContact O-N 3.11Å; E178-E180 VanDerWaalsContact C-N 3.35Å; E180-I182 PolarHBondContact O-N 2.81Å; E180-T183 PolarHBondContact O-N 3.45Å; E180-C184 PolarHBondContact O-N 3.03Å; E180-C184 PolarHBondContact O-SG 3.47Å
181I90.6Very high82.4Confident14 Ų1439.9 Ų39.97%0.07221%0.21CC..Hα-helixtrans-57.9-50.4176.9-69.6166.7000110.5L152 E153 R177 E178 T183 C184 Y185 I237L152-I181 HydrophobicContact CB-CD1 4.07Å; L152-I181 HydrophobicContact CB-CG1 3.57Å; L152-I181 HydrophobicContact CD1-CG1 4.18Å; E153-I181 HydrophobicContact CG-CD1 4.19Å; E153-I181 HydrophobicContact CG-CG2 3.88Å; R177-I181 HydrophobicContact CG-CD1 4.3Å; R177-I181 WeakPolarHBondContact O-CG1 3.37Å; R177-I181 PolarHBondContact O-N 3.39Å; E178-I181 WeakPolarHBondContact O-CB 3.44Å; E178-I181 PolarHBondContact O-N 3.34Å; I181-T183 VanDerWaalsContact C-N 3.32Å; I181-T183 PolarHBondContact O-N 2.78Å; I181-C184 WeakPolarHBondContact O-CB 3.39Å; I181-C184 PolarHBondContact O-N 2.99Å; I181-Y185 HydrophobicContact CG2-CD2 3.89Å; I181-Y185 HydrophobicContact CG2-CE2 3.39Å; I181-Y185 WeakPolarHBondContact O-CD2 3.47Å; I181-Y185 PolarHBondContact O-N 3.02Å; I181-Y185 VanDerWaalsContact O-N 3.16Å; I181-I237 HydrophobicContact CG2-CD1 4.08Å
182I90.1Very high84.5Confident1 Ų134.9 Ų34.91%0.00518%0.183CC..Hα-helixtrans-58-47.2177.3-69.1165.1000110.2E178 E180 C184 Y185 E186 I237 H238E178-I182 VanDerWaalsContact O-CG1 3.25Å; E178-I182 WeakPolarHBondContact O-CG1 3.43Å; E178-I182 PolarHBondContact O-N 2.98Å; E180-I182 PolarHBondContact O-N 2.81Å; I182-C184 VanDerWaalsContact C-N 3.27Å; I182-C184 PolarHBondContact O-N 3.21Å; I182-Y185 PolarHBondContact O-N 3.2Å; I182-Y185 VanDerWaalsContact O-N 3.09Å; I182-E186 HydrophobicContact CG2-CG 4.12Å; I182-E186 WeakPolarHBondContact O-CG 3.38Å; I182-E186 PolarHBondContact O-N 3.3Å; I182-I237 HydrophobicContact CD1-CG2 3.78Å; I182-I237 HydrophobicContact CG1-CB 4.27Å; I182-I237 HydrophobicContact CG1-CD1 4.48Å; I182-I237 HydrophobicContact CG1-CG2 3.68Å; I182-H238 VanDerWaalsContact CG2-CE1 3.45Å; I182-H238 WeakPolarHBondContact CG2-CE1 3.45Å; I182-H238 WeakPolarHBondContact CG2-NE2 3.42Å
183T91.4Very high86.5Confident23 Ų2328.7 Ų28.714%0.14116%0.16CC..Hα-helixtrans-61.4-36.7-179.5-53.70000111.7Q179 E180 I181 E186 K187 Y314Q179-T183 WeakPolarHBondContact O-CB 3.3Å; Q179-T183 PolarHBondContact O-N 2.75Å; Q179-T183 PolarHBondContact O-OG1 3.44Å; E180-T183 PolarHBondContact O-N 3.45Å; I181-T183 VanDerWaalsContact C-N 3.32Å; I181-T183 PolarHBondContact O-N 2.78Å; T183-E186 PolarHBondContact O-N 3.41Å; T183-K187 HydrophobicContact CG2-CD 4.42Å; T183-K187 WeakPolarHBondContact O-CB 3.36Å; T183-K187 WeakPolarHBondContact O-CG 3.48Å; T183-K187 PolarHBondContact O-N 3.38Å; T183-Y314 HydrophobicContact CG2-CD1 3.91Å; T183-Y314 HydrophobicContact CG2-CE1 4.41Å
184C93.4Very high88.4Confident4 Ų424.8 Ų24.83%0.02713%0.133CC..Hα-helixtrans-61.1-46.6174-67.80000111.2E180 I181 I182 S188E180-C184 PolarHBondContact O-N 3.03Å; E180-C184 PolarHBondContact O-SG 3.47Å; I181-C184 WeakPolarHBondContact O-CB 3.39Å; I181-C184 PolarHBondContact O-N 2.99Å; I182-C184 VanDerWaalsContact C-N 3.27Å; I182-C184 PolarHBondContact O-N 3.21Å; C184-S188 VanDerWaalsContact O-CB 3.27Å; C184-S188 WeakPolarHBondContact O-CB 3.3Å; C184-S188 PolarHBondContact O-N 2.85Å
185Y95.1Very high90Very high0 Ų023.5 Ų23.50%012%0.122CC..Hα-helixtrans-69.1-36.8177.7-63.8-55.6000113.1G149 L150 E153 I181 I182 S188 G189 T229 G230 R233 I237G149-Y185 VanDerWaalsContact C-OH 3.32Å; L150-Y185 HydrophobicContact CG-CE1 4.35Å; L150-Y185 PolarHBondContact N-OH 3.38Å; E153-Y185 WeakPolarHBondContact OE1-CE2 3.43Å; E153-Y185 PolarHBondContact OE1-OH 3.4Å; I181-Y185 HydrophobicContact CG2-CD2 3.89Å; I181-Y185 HydrophobicContact CG2-CE2 3.39Å; I181-Y185 WeakPolarHBondContact O-CD2 3.47Å; I181-Y185 PolarHBondContact O-N 3.02Å; I181-Y185 VanDerWaalsContact O-N 3.16Å; I182-Y185 PolarHBondContact O-N 3.2Å; I182-Y185 VanDerWaalsContact O-N 3.09Å; Y185-S188 WeakPolarHBondContact O-CB 3.22Å; Y185-S188 PolarHBondContact O-N 3.12Å; Y185-G189 PolarHBondContact O-N 2.71Å; Y185-T229 HydrophobicContact CD1-CG2 4.44Å; Y185-T229 HydrophobicContact CE1-CG2 3.85Å; Y185-G230 VanDerWaalsContact O-O 3.09Å; Y185-R233 HydrophobicContact CD1-CB 3.9Å; Y185-R233 HydrophobicContact CD1-CG 4.11Å; Y185-R233 HydrophobicContact CD2-CB 4.03Å; Y185-R233 HydrophobicContact CD2-CG 3.62Å; Y185-R233 HydrophobicContact CE1-CB 4.05Å; Y185-R233 HydrophobicContact CE1-CG 3.88Å; Y185-R233 HydrophobicContact CE2-CB 4.14Å; Y185-R233 HydrophobicContact CE2-CG 3.32Å; Y185-R233 HydrophobicContact CG-CB 3.89Å; Y185-R233 HydrophobicContact CG-CG 3.99Å; Y185-R233 VanDerWaalsContact CZ-CG 3.45Å; Y185-I237 HydrophobicContact CD2-CD1 3.84Å; Y185-I237 HydrophobicContact CE2-CD1 3.76Å
186E93.4Very high91Very high18 Ų1822.4 Ų22.48%0.08412%0.115CC..Hα-helixtrans-62.6-47.6175.9-70179.7161.300111.5I182 T183 S188 G189 D190 A234 H238 Y314I182-E186 HydrophobicContact CG2-CG 4.12Å; I182-E186 WeakPolarHBondContact O-CG 3.38Å; I182-E186 PolarHBondContact O-N 3.3Å; T183-E186 PolarHBondContact O-N 3.41Å; E186-S188 PolarHBondContact O-N 3.37Å; E186-G189 PolarHBondContact O-N 3.08Å; E186-D190 WeakPolarHBondContact O-CB 3.36Å; E186-D190 VanDerWaalsContact O-CG 3.23Å; E186-D190 PolarHBondContact O-N 2.96Å; E186-A234 HydrophobicContact CG-CB 3.86Å; E186-H238 IonicContact OE1-CD2 3.72Å; E186-H238 IonicContact OE1-CE1 3.12Å; E186-H238 IonicContact OE1-NE2 3.26Å; E186-H238 PolarHBondContact OE1-NE2 2.86Å; E186-Y314 VanDerWaalsContact C-OH 3.25Å; E186-Y314 HydrophobicContact CB-CE1 3.83Å; E186-Y314 WeakPolarHBondContact CB-OH 3.38Å; E186-Y314 PolarHBondContact O-OH 3.06Å
187K93.8Very high91.8Very high21 Ų2117.6 Ų17.69%0.0918%0.082CC..Hα-helixtrans-60.5-44.3173.2-72.4-177.1-179-178.70111.5D126 Y145 T183 D190 I191 Y314 L316D126-K187 IonicContact OD1-NZ 2.94Å; D126-K187 PolarHBondContact OD1-NZ 3.09Å; D126-K187 IonicContact OD2-NZ 2.79Å; D126-K187 PolarHBondContact OD2-NZ 3.03Å; Y145-K187 HydrophobicContact CD1-CB 4.17Å; Y145-K187 HydrophobicContact CD1-CD 4.27Å; Y145-K187 HydrophobicContact CD2-CB 4.31Å; Y145-K187 HydrophobicContact CE1-CB 4.28Å; Y145-K187 HydrophobicContact CE1-CD 3.62Å; Y145-K187 HydrophobicContact CE2-CB 4.4Å; Y145-K187 HydrophobicContact CG-CB 4.19Å; T183-K187 HydrophobicContact CG2-CD 4.42Å; T183-K187 WeakPolarHBondContact O-CB 3.36Å; T183-K187 WeakPolarHBondContact O-CG 3.48Å; T183-K187 PolarHBondContact O-N 3.38Å; K187-D190 PolarHBondContact O-N 3.34Å; K187-I191 WeakPolarHBondContact O-CB 3.5Å; K187-I191 WeakPolarHBondContact O-CD1 3.42Å; K187-I191 WeakPolarHBondContact O-CG1 3.45Å; K187-I191 PolarHBondContact O-N 3.22Å; K187-Y314 HydrophobicContact CD-CD2 4.41Å; K187-Y314 HydrophobicContact CD-CG 4.45Å; K187-Y314 HydrophobicContact CG-CD1 4.17Å; K187-Y314 HydrophobicContact CG-CD2 3.74Å; K187-Y314 HydrophobicContact CG-CE1 4.11Å; K187-Y314 HydrophobicContact CG-CE2 3.68Å; K187-Y314 HydrophobicContact CG-CG 4Å; K187-L316 HydrophobicContact CG-CD2 4.45Å
188S95.4Very high92.2Very high0 Ų016.6 Ų16.60%08%0.08CC..Hα-helixtrans-58.3-50.5177.3-178.90000111.9A142 A146 C184 Y185 E186 I191 A192 G230A142-S188 WeakPolarHBondContact O-CB 3.4Å; A142-S188 PolarHBondContact O-OG 2.82Å; A146-S188 WeakPolarHBondContact CB-OG 3.47Å; C184-S188 VanDerWaalsContact O-CB 3.27Å; C184-S188 WeakPolarHBondContact O-CB 3.3Å; C184-S188 PolarHBondContact O-N 2.85Å; Y185-S188 WeakPolarHBondContact O-CB 3.22Å; Y185-S188 PolarHBondContact O-N 3.12Å; E186-S188 PolarHBondContact O-N 3.37Å; S188-I191 PolarHBondContact O-N 2.96Å; S188-A192 WeakPolarHBondContact O-CB 3.45Å; S188-A192 PolarHBondContact O-N 3.44Å; S188-G230 VanDerWaalsContact OG-CA 3.31Å; S188-G230 WeakPolarHBondContact OG-CA 3.33Å
189G94.6Very high92.5Very high0 Ų013.6 Ų13.60%07%0.067CC..Hα-helixtrans-63-42.3179.400000113Y185 E186 A192 L193 G230Y185-G189 PolarHBondContact O-N 2.71Å; E186-G189 PolarHBondContact O-N 3.08Å; G189-A192 PolarHBondContact O-N 3.45Å; G189-L193 WeakPolarHBondContact O-CG 3.45Å; G189-L193 PolarHBondContact O-N 3.43Å; G189-G230 WeakPolarHBondContact CA-O 3.21Å; G189-G230 PolarHBondContact N-O 3.41Å
190D94.9Very high92.6Very high11 Ų1114.4 Ų14.46%0.0597%0.07CC..Hα-helixtrans-65.2-42.4179.2-69.72.3000111.7E186 K187 L194 R250 K312 Y314 L316E186-D190 WeakPolarHBondContact O-CB 3.36Å; E186-D190 VanDerWaalsContact O-CG 3.23Å; E186-D190 PolarHBondContact O-N 2.96Å; K187-D190 PolarHBondContact O-N 3.34Å; D190-L194 PolarHBondContact O-N 3.17Å; D190-R250 IonicContact OD1-CZ 2.59Å; D190-R250 VanDerWaalsContact OD1-CZ 3.3Å; D190-R250 IonicContact OD1-NH1 2.94Å; D190-R250 PolarHBondContact OD1-NH1 3.44Å; D190-R250 IonicContact OD1-NH2 3.57Å; D190-R250 PolarHBondContact OD1-NH2 3.43Å; D190-R250 IonicContact OD2-NH1 3.99Å; D190-K312 IonicContact OD2-NZ 3.67Å; D190-K312 PolarHBondContact OD2-NZ 3.4Å; D190-Y314 PolarHBondContact OD2-OH 3.01Å; D190-L316 HydrophobicContact CB-CD1 3.54Å
191I95.2Very high92.6Very high2 Ų215.7 Ų15.71%0.017%0.074CC..Hα-helixtrans-72.2-35177.2-60.3167.2000110.6L130 L138 I141 A142 Y145 K187 S188 L194 Y195 L316L130-I191 HydrophobicContact CD1-CD1 4.22Å; L130-I191 HydrophobicContact CD1-CG1 4.09Å; L130-I191 HydrophobicContact CD2-CD1 4.18Å; L130-I191 HydrophobicContact CD2-CG1 4.37Å; L130-I191 HydrophobicContact CD2-CG2 4.16Å; L138-I191 WeakPolarHBondContact O-CG2 3.46Å; I141-I191 HydrophobicContact CG2-CD1 3.82Å; I141-I191 HydrophobicContact CG2-CG2 4.43Å; A142-I191 HydrophobicContact CB-CB 4.15Å; A142-I191 HydrophobicContact CB-CG2 3.97Å; Y145-I191 HydrophobicContact CD2-CD1 3.9Å; Y145-I191 HydrophobicContact CE2-CD1 3.78Å; K187-I191 WeakPolarHBondContact O-CB 3.5Å; K187-I191 WeakPolarHBondContact O-CD1 3.42Å; K187-I191 WeakPolarHBondContact O-CG1 3.45Å; K187-I191 PolarHBondContact O-N 3.22Å; S188-I191 PolarHBondContact O-N 2.96Å; I191-L194 WeakPolarHBondContact O-CB 3.39Å; I191-L194 PolarHBondContact O-N 2.9Å; I191-Y195 WeakPolarHBondContact O-CB 3.45Å; I191-Y195 PolarHBondContact O-N 3.33Å; I191-L316 HydrophobicContact CD1-CD2 4.4Å; I191-L316 HydrophobicContact CG1-CD1 3.97Å; I191-L316 HydrophobicContact CG1-CD2 4.47Å
192A95.1Very high92.1Very high0 Ų017.4 Ų17.40%09%0.091CC..Hα-helixtrans-61.9-44.8174.200000111.4A142 S188 G189 L194 Y195 L196 L227 L231A142-A192 HydrophobicContact CB-CB 4.11Å; S188-A192 WeakPolarHBondContact O-CB 3.45Å; S188-A192 PolarHBondContact O-N 3.44Å; G189-A192 PolarHBondContact O-N 3.45Å; A192-L194 VanDerWaalsContact C-N 3.32Å; A192-L194 PolarHBondContact O-N 3.13Å; A192-Y195 WeakPolarHBondContact O-CB 3.11Å; A192-Y195 PolarHBondContact O-N 2.89Å; A192-L196 VanDerWaalsContact O-CG 3.27Å; A192-L196 WeakPolarHBondContact O-CG 3.28Å; A192-L196 PolarHBondContact O-N 3.14Å; A192-L227 HydrophobicContact CB-CD2 4Å; A192-L231 HydrophobicContact CB-CD2 4.18Å; A192-L231 HydrophobicContact CB-CG 4.15Å
193L94.9Very high91.6Very high8 Ų820.7 Ų20.74%0.04211%0.108CC..Hα-helixtrans-59.7-42.6174.3-71.6171.9000111.8G189 L196 Q197 L231 I254 A257 T263 P320G189-L193 WeakPolarHBondContact O-CG 3.45Å; G189-L193 PolarHBondContact O-N 3.43Å; L193-L196 PolarHBondContact O-N 3.27Å; L193-Q197 VanDerWaalsContact O-CG 3.31Å; L193-Q197 WeakPolarHBondContact O-CG 3.42Å; L193-Q197 PolarHBondContact O-N 3.37Å; L193-Q197 VanDerWaalsContact O-N 3.15Å; L193-L231 HydrophobicContact CD2-CD2 3.81Å; L193-L231 HydrophobicContact CG-CD2 3.74Å; L193-I254 HydrophobicContact CD1-CG1 4.41Å; L193-A257 HydrophobicContact CD1-CB 3.93Å; L193-A257 HydrophobicContact CD2-CB 4.38Å; L193-T263 HydrophobicContact CD2-CG2 4.13Å; L193-P320 HydrophobicContact CB-CB 3.9Å; L193-P320 HydrophobicContact CB-CG 4.17Å
194L94.8Very high90.8Very high2 Ų222.4 Ų22.41%0.0112%0.121CC..Hα-helixtrans-62.1-45.7175.6174.266.3000111.6L138 D190 I191 A192 Q197 E198 R318 P320L138-L194 HydrophobicContact CD1-CD2 4.36Å; L138-L194 HydrophobicContact CD1-CG 4.25Å; L138-L194 HydrophobicContact CD2-CD2 4.15Å; D190-L194 PolarHBondContact O-N 3.17Å; I191-L194 WeakPolarHBondContact O-CB 3.39Å; I191-L194 PolarHBondContact O-N 2.9Å; A192-L194 VanDerWaalsContact C-N 3.32Å; A192-L194 PolarHBondContact O-N 3.13Å; L194-Q197 PolarHBondContact O-N 2.65Å; L194-E198 HydrophobicContact CD1-CG 4.16Å; L194-E198 WeakPolarHBondContact O-CG 3.44Å; L194-E198 PolarHBondContact O-N 3.41Å; L194-E198 VanDerWaalsContact O-N 3.07Å; L194-R318 HydrophobicContact CD1-CG 4.23Å; L194-R318 HydrophobicContact CD2-CB 4.28Å; L194-R318 HydrophobicContact CD2-CG 3.92Å; L194-R318 WeakPolarHBondContact CD2-O 3.43Å; L194-P320 HydrophobicContact CB-CB 4.34Å
195Y93.4Very high89.6Confident18 Ų1824.8 Ų24.87%0.07114%0.141CC..Hα-helixtrans-56.8-51.7176.4155.9-111.7000111.2V135 I191 A192 Q197 E198 A199 L227V135-Y195 HydrophobicContact CG1-CD2 3.76Å; V135-Y195 HydrophobicContact CG1-CE2 3.73Å; V135-Y195 WeakPolarHBondContact O-CD2 3.38Å; I191-Y195 WeakPolarHBondContact O-CB 3.45Å; I191-Y195 PolarHBondContact O-N 3.33Å; A192-Y195 WeakPolarHBondContact O-CB 3.11Å; A192-Y195 PolarHBondContact O-N 2.89Å; Y195-Q197 VanDerWaalsContact C-N 3.31Å; Y195-Q197 PolarHBondContact O-N 3.49Å; Y195-E198 PolarHBondContact O-N 3.26Å; Y195-A199 HydrophobicContact CD2-CB 4.4Å; Y195-A199 HydrophobicContact CE2-CB 4.01Å; Y195-A199 VanDerWaalsContact O-CB 3.31Å; Y195-A199 WeakPolarHBondContact O-CB 3.28Å; Y195-A199 PolarHBondContact O-N 3.03Å; Y195-L227 HydrophobicContact CD1-CD1 4.05Å; Y195-L227 HydrophobicContact CE1-CD1 3.63Å
196L92.9Very high87.7Confident3 Ų325.7 Ų25.72%0.01615%0.151CC..Hα-helixtrans-61.4-40.2-176.9-65.7172.1000111.8A192 L193 A199 E200 L221 L223 L231 T260 T263A192-L196 VanDerWaalsContact O-CG 3.27Å; A192-L196 WeakPolarHBondContact O-CG 3.28Å; A192-L196 PolarHBondContact O-N 3.14Å; L193-L196 PolarHBondContact O-N 3.27Å; L196-A199 PolarHBondContact O-N 3.41Å; L196-E200 WeakPolarHBondContact O-CB 3.45Å; L196-E200 PolarHBondContact O-N 3.03Å; L196-L221 HydrophobicContact CD2-CD2 3.97Å; L196-L223 HydrophobicContact CD1-CD1 3.88Å; L196-L223 HydrophobicContact CD2-CD1 4Å; L196-L231 HydrophobicContact CD1-CD1 4.3Å; L196-T260 HydrophobicContact CB-CG2 4.35Å; L196-T263 HydrophobicContact CD1-CG2 3.59Å
197Q92.8Very high85.9Confident17 Ų1730.1 Ų30.18%0.07917%0.174CC..Hα-helixtrans-65.5-41.6176.5-71.9175.4-4.800112.6L193 L194 Y195 K201 V258 T260 R321L193-Q197 VanDerWaalsContact O-CG 3.31Å; L193-Q197 WeakPolarHBondContact O-CG 3.42Å; L193-Q197 PolarHBondContact O-N 3.37Å; L193-Q197 VanDerWaalsContact O-N 3.15Å; L194-Q197 PolarHBondContact O-N 2.65Å; Y195-Q197 VanDerWaalsContact C-N 3.31Å; Y195-Q197 PolarHBondContact O-N 3.49Å; Q197-K201 WeakPolarHBondContact O-CB 3.3Å; Q197-K201 PolarHBondContact O-N 2.66Å; Q197-K201 VanDerWaalsContact O-N 3.15Å; Q197-V258 PolarHBondContact NE2-O 2.93Å; Q197-T260 HydrophobicContact CB-CG2 4.3Å; Q197-T260 HydrophobicContact CG-CG2 3.67Å; Q197-R321 PolarHBondContact NE2-O 3.23Å
198E90.3Very high83.8Confident24 Ų2437.4 Ų37.411%0.11221%0.208CC..Hα-helixtrans-75.6-32.3179.2-66.4-66.3147.600112V135 L194 Y195 K201 A202 R318 R321V135-E198 HydrophobicContact CG2-CB 4.29Å; L194-E198 HydrophobicContact CD1-CG 4.16Å; L194-E198 WeakPolarHBondContact O-CG 3.44Å; L194-E198 PolarHBondContact O-N 3.41Å; L194-E198 VanDerWaalsContact O-N 3.07Å; Y195-E198 PolarHBondContact O-N 3.26Å; E198-K201 PolarHBondContact O-N 3Å; E198-A202 WeakPolarHBondContact O-CB 3.29Å; E198-A202 PolarHBondContact O-N 3.42Å; E198-R318 IonicContact OE1-NH2 2.78Å; E198-R318 PolarHBondContact OE1-NH2 3.15Å; E198-R318 IonicContact OE2-NH2 2.87Å; E198-R318 PolarHBondContact OE2-NH2 3.15Å; E198-R321 IonicContact OE1-CZ 2.72Å; E198-R321 IonicContact OE1-NE 2.69Å; E198-R321 IonicContact OE1-NH2 3.31Å; E198-R321 PolarHBondContact OE1-NH2 2.74Å
199A88.1Confident81.4Confident5 Ų544.4 Ų44.44%0.04125%0.246CC..Hα-helixtrans-63.2-47.1172.900000111.7V135 Y195 L196 K201 A202 L203 L221V135-A199 HydrophobicContact CG1-CB 3.81Å; Y195-A199 HydrophobicContact CD2-CB 4.4Å; Y195-A199 HydrophobicContact CE2-CB 4.01Å; Y195-A199 VanDerWaalsContact O-CB 3.31Å; Y195-A199 WeakPolarHBondContact O-CB 3.28Å; Y195-A199 PolarHBondContact O-N 3.03Å; L196-A199 PolarHBondContact O-N 3.41Å; A199-K201 VanDerWaalsContact C-N 3.34Å; A199-K201 PolarHBondContact O-N 3.45Å; A199-A202 PolarHBondContact O-N 3.12Å; A199-L203 WeakPolarHBondContact O-CG 3.45Å; A199-L203 PolarHBondContact O-N 3.43Å; A199-L221 HydrophobicContact CB-CD2 4.04Å
200E87.1Confident79Confident50 Ų5052.4 Ų52.423%0.23428%0.276CS..Hα-helixtrans-64.5-38.4177-172.7174.3-126.600112.3L196 L203 S204 T260 R261L196-E200 WeakPolarHBondContact O-CB 3.45Å; L196-E200 PolarHBondContact O-N 3.03Å; E200-L203 PolarHBondContact O-N 3.12Å; E200-S204 WeakPolarHBondContact O-CB 3.46Å; E200-S204 PolarHBondContact O-N 3.15Å; E200-S204 PolarHBondContact O-OG 3.11Å; E200-T260 VanDerWaalsContact OE2-CA 3.31Å; E200-T260 WeakPolarHBondContact OE2-CA 3.41Å; E200-T260 WeakPolarHBondContact OE2-CB 3.25Å; E200-T260 WeakPolarHBondContact OE2-CG2 3.5Å; E200-R261 VanDerWaalsContact OE1-CG 3.28Å; E200-R261 WeakPolarHBondContact OE1-CG 3.49Å; E200-R261 PolarHBondContact OE1-N 3.05Å; E200-R261 IonicContact OE1-NE 3.85Å
201K86.7Confident76.1Confident108 Ų10856.7 Ų56.747%0.4731%0.306SS..Hα-helixtrans-62.5-43173.7-175.3-176.2177-170.70111.8Q197 E198 A199 S204 A205 R321Q197-K201 WeakPolarHBondContact O-CB 3.3Å; Q197-K201 PolarHBondContact O-N 2.66Å; Q197-K201 VanDerWaalsContact O-N 3.15Å; E198-K201 PolarHBondContact O-N 3Å; A199-K201 VanDerWaalsContact C-N 3.34Å; A199-K201 PolarHBondContact O-N 3.45Å; K201-S204 PolarHBondContact O-N 3.46Å; K201-A205 PolarHBondContact O-N 3.44Å; K201-A205 VanDerWaalsContact O-N 3.07Å; K201-R321 VanDerWaalsContact NZ-NH2 3.19Å
202A81.7Confident73.3Confident50 Ų5063 Ų6341%0.41335%0.347SS..Hα-helixtrans-64.8-43.1177.700000111.8E198 A199 S204 A205 G206E198-A202 WeakPolarHBondContact O-CB 3.29Å; E198-A202 PolarHBondContact O-N 3.42Å; A199-A202 PolarHBondContact O-N 3.12Å; A202-S204 PolarHBondContact O-N 2.65Å; A202-A205 PolarHBondContact O-N 2.89Å; A202-G206 PolarHBondContact O-N 3.29Å
203L77.9Confident70.1Confident70 Ų7071.6 Ų71.637%0.36639%0.385SS..Hα-helixtrans-61.2-42.9175.1-72.7165.4000111.8E20 A199 E200 G206 I207E20-L203 HydrophobicContact CG-CD2 4.37Å; A199-L203 WeakPolarHBondContact O-CG 3.45Å; A199-L203 PolarHBondContact O-N 3.43Å; E200-L203 PolarHBondContact O-N 3.12Å; L203-G206 PolarHBondContact O-N 3.02Å; L203-I207 WeakPolarHBondContact O-CG1 3.49Å; L203-I207 PolarHBondContact O-N 3.25Å
204S75.6Confident67.1Low60 Ų6077.9 Ų77.942%0.4243%0.426SS..Hα-helixtrans-66.1-38.9179.5-59.90000113E200 K201 A202 G206 I207E200-S204 WeakPolarHBondContact O-CB 3.46Å; E200-S204 PolarHBondContact O-N 3.15Å; E200-S204 PolarHBondContact O-OG 3.11Å; K201-S204 PolarHBondContact O-N 3.46Å; A202-S204 PolarHBondContact O-N 2.65Å; S204-G206 VanDerWaalsContact C-N 3.31Å; S204-G206 PolarHBondContact O-N 3.42Å; S204-I207 PolarHBondContact O-N 3.34Å
205A67.4Low64Low53 Ų5380.4 Ų80.444%0.43845%0.452SS..Hα-helixtrans-68.2-29.7175.700000112.9K201 A202 I207K201-A205 PolarHBondContact O-N 3.44Å; K201-A205 VanDerWaalsContact O-N 3.07Å; A202-A205 PolarHBondContact O-N 2.89Å; A205-I207 VanDerWaalsContact C-N 3.3Å; A205-I207 PolarHBondContact O-N 2.86Å
206G56.2Low61Low20 Ų2086 Ų8621%0.20649%0.491CS..Hα-helixtrans-68.2-25.8175.800000114.2A202 L203 S204A202-G206 PolarHBondContact O-N 3.29Å; L203-G206 PolarHBondContact O-N 3.02Å; S204-G206 VanDerWaalsContact C-N 3.31Å; S204-G206 PolarHBondContact O-N 3.42Å
207I54.4Low58.2Low111 Ų11190.1 Ų90.157%0.56953%0.526SS*.Hα-helixtrans-77.5-36.6-178.6-65.7166.3000111.6L203 S204 A205 N209 R210L203-I207 WeakPolarHBondContact O-CG1 3.49Å; L203-I207 PolarHBondContact O-N 3.25Å; S204-I207 PolarHBondContact O-N 3.34Å; A205-I207 VanDerWaalsContact C-N 3.3Å; A205-I207 PolarHBondContact O-N 2.86Å; I207-N209 PolarHBondContact O-N 2.86Å; I207-R210 PolarHBondContact O-N 3.4Å
208Q51.5Low55.7Low174 Ų17494.2 Ų94.281%0.81355%0.552SS**Hα-helixtrans-67.3-20.3178.3-69.9-175.9-1300113.6
209N45.2Very low53.9Low147 Ų14799.8 Ų99.879%0.78658%0.578SS**THydrogen-bonded Turntrans-99.87-177.4-74.8-31.1000114.4I207I207-N209 PolarHBondContact O-N 2.86Å
210R43.3Very low52.5Low168 Ų168105.9 Ų105.963%0.63461%0.61SS**SBendtrans-115.3129176.5-72.2-177.1175.5174.92.9110.5I207I207-R210 PolarHBondContact O-N 3.4Å
211S33Very low51.7Low100 Ų100105.8 Ų105.870%0.69961%0.611SS**  trans-64.2146.9166.3450000110.1K213S211-K213 PolarHBondContact O-N 2.88Å
212P36.3Very low51.1Low134 Ų134108.9 Ų108.987%0.8763%0.627SS**  trans-70.498.7-173.328.2-32000109.4
213K29Very low51.2Low181 Ų181108 Ų10879%0.78762%0.615SS**  trans-113138.3161-84.3-173.2175.7-178.10108.6S211 G215S211-K213 PolarHBondContact O-N 2.88Å; K213-G215 PolarHBondContact O-N 2.85Å
214P32.4Very low51.6Low140 Ų140106.2 Ų106.291%0.90961%0.614SS**  trans-74.893178.830.3-28.3000108.4
215G29Very low52.3Low55 Ų55104.9 Ų104.957%0.56760%0.6SS**  trans-102.5165.8164.800000110.1K213K213-G215 PolarHBondContact O-N 2.85Å
216P30Very low53.4Low135 Ų135102.6 Ų102.688%0.87758%0.58SS**SBendtrans-59.5148.5-169.727.3-34.5000111.4
217A33.9Very low55.1Low91 Ų91101.9 Ų101.975%0.75257%0.572SS**  trans-38.5138.7-175.500000113Q219A217-Q219 PolarHBondContact O-N 2.99Å
218T41.5Very low56.8Low103 Ų103100.6 Ų100.663%0.63256%0.563SS**  trans-44115.3171.239.60000109.7D220T218-D220 PolarHBondContact O-N 2.79Å; T218-D220 VanDerWaalsContact O-N 3.15Å
219Q52Low58.8Low140 Ų14093 Ų9365%0.65453%0.528SS*.  trans-64.6114.3171.8-97.5171.8-21.700107.9A217 L221A217-Q219 PolarHBondContact O-N 2.99Å; Q219-L221 PolarHBondContact O-N 3.48Å
220D58.6Low61Low134 Ų13486 Ų8672%0.71749%0.491SS*.  trans-66.1128.9172.4-69.5-37.7000108.7T218 E222T218-D220 PolarHBondContact O-N 2.79Å; T218-D220 VanDerWaalsContact O-N 3.15Å; D220-E222 PolarHBondContact O-N 3.29Å; D220-E222 VanDerWaalsContact O-N 3.12Å
221L69.8Low63.4Low47 Ų4778 Ų7825%0.24646%0.461CS..  trans-66.6108.4175.7-17672.8000108L196 A199 Q219 T262L196-L221 HydrophobicContact CD2-CD2 3.97Å; A199-L221 HydrophobicContact CB-CD2 4.04Å; Q219-L221 PolarHBondContact O-N 3.48Å; L221-T262 HydrophobicContact CB-CG2 3.87Å; L221-T262 HydrophobicContact CD2-CG2 4.17Å; L221-T262 HydrophobicContact CG-CG2 4.26Å; L221-T262 WeakPolarHBondContact O-CG2 3.23Å
222E75.8Confident66.2Low174 Ų17477.2 Ų77.281%0.81345%0.446SS*.  trans-85.1140.5179-164.1175.1-176.200110.8D220 G224D220-E222 PolarHBondContact O-N 3.29Å; D220-E222 VanDerWaalsContact O-N 3.12Å; E222-G224 PolarHBondContact O-N 3.11Å
223L83.8Confident68.9Low30 Ų3072.9 Ų72.916%0.15741%0.412CS..  trans-80.6114.6-177.7-160.367.1000109.7L196 L227 E228 L231L196-L223 HydrophobicContact CD1-CD1 3.88Å; L196-L223 HydrophobicContact CD2-CD1 4Å; L223-L227 HydrophobicContact CD1-CB 3.85Å; L223-L227 HydrophobicContact CD1-CD1 4.23Å; L223-L227 HydrophobicContact CG-CB 4.2Å; L223-E228 HydrophobicContact CB-CG 4.04Å; L223-E228 HydrophobicContact CD2-CB 4.47Å; L223-E228 HydrophobicContact CD2-CG 3.55Å; L223-E228 HydrophobicContact CG-CG 3.67Å; L223-L231 HydrophobicContact CD1-CD1 4.21Å; L223-L231 HydrophobicContact CD2-CD1 3.83Å
224G85.8Confident71.9Confident33 Ų3364.3 Ų64.334%0.3438%0.375SS..  trans-72.8155.7179.700000113.4E222 F226 L227 E228E222-G224 PolarHBondContact O-N 3.11Å; G224-F226 VanDerWaalsContact C-N 3.26Å; G224-F226 PolarHBondContact O-N 3.24Å; G224-F226 VanDerWaalsContact O-N 3.08Å; G224-L227 PolarHBondContact O-N 3.11Å; G224-E228 PolarHBondContact O-N 3.29Å
225Y89.3Confident74.7Confident32 Ų3258 Ų5813%0.12533%0.333CS..Hα-helixtrans-45-43.9-179.3169.7-106000114.6I62 Q64 L150 T229I62-Y225 HydrophobicContact CB-CD1 3.81Å; I62-Y225 HydrophobicContact CB-CD2 4.37Å; I62-Y225 HydrophobicContact CB-CE1 4.28Å; I62-Y225 HydrophobicContact CB-CG 3.86Å; I62-Y225 HydrophobicContact CD1-CD1 4.26Å; I62-Y225 HydrophobicContact CG2-CD1 3.72Å; I62-Y225 HydrophobicContact CG2-CD2 4.27Å; I62-Y225 HydrophobicContact CG2-CE1 3.65Å; I62-Y225 HydrophobicContact CG2-CE2 4.22Å; I62-Y225 HydrophobicContact CG2-CG 4.04Å; I62-Y225 WeakPolarHBondContact O-CD2 3.46Å; Q64-Y225 HydrophobicContact CB-CE2 4.38Å; L150-Y225 HydrophobicContact CD1-CE1 4Å; Y225-T229 VanDerWaalsContact O-CB 3.31Å; Y225-T229 WeakPolarHBondContact O-CB 3.47Å; Y225-T229 PolarHBondContact O-N 3.07Å; Y225-T229 PolarHBondContact O-OG1 3.03Å
226F91.4Very high77.7Confident5 Ų557.7 Ų57.72%0.02232%0.32CS..Hα-helixtrans-70.2-38.4-178.3-63.2-69.4000112.4L57 I62 K105 Y108 E143 A146 T147 L150 G224 T229 G230L57-F226 HydrophobicContact CD1-CE2 4.3Å; I62-F226 HydrophobicContact CD1-CE2 4.13Å; I62-F226 HydrophobicContact CD1-CZ 3.83Å; K105-F226 HydrophobicContact CD-CE2 4.1Å; K105-F226 HydrophobicContact CG-CE2 4.21Å; K105-F226 HydrophobicContact CG-CZ 4.21Å; Y108-F226 AromaticContact CD1-CE1 3.73Å; Y108-F226 HydrophobicContact CD1-CE1 3.73Å; Y108-F226 AromaticContact CD1-CZ 3.93Å; Y108-F226 HydrophobicContact CD1-CZ 3.93Å; Y108-F226 AromaticContact CE1-CE1 3.59Å; Y108-F226 HydrophobicContact CE1-CE1 3.59Å; Y108-F226 HydrophobicContact CE1-CZ 4.01Å; E143-F226 HydrophobicContact CB-CB 4.06Å; E143-F226 HydrophobicContact CG-CB 3.88Å; A146-F226 HydrophobicContact CB-CB 4.42Å; A146-F226 VanDerWaalsContact CB-O 3.25Å; A146-F226 WeakPolarHBondContact CB-O 3.4Å; T147-F226 VanDerWaalsContact OG1-CD1 3.31Å; T147-F226 WeakPolarHBondContact OG1-CD1 3.38Å; T147-F226 WeakPolarHBondContact OG1-CE1 3.3Å; L150-F226 HydrophobicContact CD1-CD1 4.1Å; L150-F226 HydrophobicContact CD1-CE1 4.25Å; G224-F226 VanDerWaalsContact C-N 3.26Å; G224-F226 PolarHBondContact O-N 3.24Å; G224-F226 VanDerWaalsContact O-N 3.08Å; F226-T229 PolarHBondContact O-N 3.44Å; F226-G230 PolarHBondContact O-N 3.04Å
227L91.2Very high80.5Confident6 Ų652.1 Ų52.13%0.03128%0.283CS..Hα-helixtrans-71-41.2176.6-65178000111.2A142 E143 A192 Y195 L223 G224 T229 G230 L231A142-L227 HydrophobicContact CB-CD2 3.77Å; E143-L227 HydrophobicContact CG-CD2 3.85Å; E143-L227 HydrophobicContact CG-CG 4.06Å; A192-L227 HydrophobicContact CB-CD2 4Å; Y195-L227 HydrophobicContact CD1-CD1 4.05Å; Y195-L227 HydrophobicContact CE1-CD1 3.63Å; L223-L227 HydrophobicContact CD1-CB 3.85Å; L223-L227 HydrophobicContact CD1-CD1 4.23Å; L223-L227 HydrophobicContact CG-CB 4.2Å; G224-L227 PolarHBondContact O-N 3.11Å; L227-T229 VanDerWaalsContact C-N 3.32Å; L227-T229 PolarHBondContact O-N 3.13Å; L227-G230 PolarHBondContact O-N 3.17Å; L227-L231 WeakPolarHBondContact O-CB 3.42Å; L227-L231 WeakPolarHBondContact O-CG 3.41Å; L227-L231 PolarHBondContact O-N 2.9Å
228E91.3Very high83Confident84 Ų8447.9 Ų47.939%0.39325%0.248SC..Hα-helixtrans-57.5-46.6171.5-71.5-174.5154.500111.4L223 G224 L231 Q232L223-E228 HydrophobicContact CB-CG 4.04Å; L223-E228 HydrophobicContact CD2-CB 4.47Å; L223-E228 HydrophobicContact CD2-CG 3.55Å; L223-E228 HydrophobicContact CG-CG 3.67Å; G224-E228 PolarHBondContact O-N 3.29Å; E228-L231 PolarHBondContact O-N 3.16Å; E228-Q232 WeakPolarHBondContact O-CB 3.19Å; E228-Q232 PolarHBondContact O-N 3.07Å
229T92.3Very high85.2Confident13 Ų1345.5 Ų45.58%0.0823%0.229CC..Hα-helixtrans-61.5-46.3177-59.40000110.9L150 Y185 Y225 F226 L227 L231 Q232 R233L150-T229 HydrophobicContact CD1-CG2 4.12Å; L150-T229 HydrophobicContact CD2-CG2 4.04Å; L150-T229 HydrophobicContact CG-CG2 4.16Å; Y185-T229 HydrophobicContact CD1-CG2 4.44Å; Y185-T229 HydrophobicContact CE1-CG2 3.85Å; Y225-T229 VanDerWaalsContact O-CB 3.31Å; Y225-T229 WeakPolarHBondContact O-CB 3.47Å; Y225-T229 PolarHBondContact O-N 3.07Å; Y225-T229 PolarHBondContact O-OG1 3.03Å; F226-T229 PolarHBondContact O-N 3.44Å; L227-T229 VanDerWaalsContact C-N 3.32Å; L227-T229 PolarHBondContact O-N 3.13Å; T229-L231 VanDerWaalsContact C-N 3.33Å; T229-L231 PolarHBondContact O-N 3.3Å; T229-Q232 PolarHBondContact O-N 2.88Å; T229-R233 HydrophobicContact CG2-CB 4.02Å; T229-R233 HydrophobicContact CG2-CG 4.44Å; T229-R233 WeakPolarHBondContact O-CB 3.29Å; T229-R233 PolarHBondContact O-N 2.8Å
230G92.5Very high86.9Confident0 Ų045.4 Ų45.40%023%0.226CC..Hα-helixtrans-58.7-42177.600000113.2Y185 S188 G189 F226 L227Y185-G230 VanDerWaalsContact O-O 3.09Å; S188-G230 VanDerWaalsContact OG-CA 3.31Å; S188-G230 WeakPolarHBondContact OG-CA 3.33Å; G189-G230 WeakPolarHBondContact CA-O 3.21Å; G189-G230 PolarHBondContact N-O 3.41Å; F226-G230 PolarHBondContact O-N 3.04Å; L227-G230 PolarHBondContact O-N 3.17Å
231L93.1Very high88Confident2 Ų240.9 Ų40.91%0.0120%0.202CC..Hα-helixtrans-70.6-38.2-179.9-73.9164.1000112.9A192 L193 L196 L223 L227 E228 T229 L266A192-L231 HydrophobicContact CB-CD2 4.18Å; A192-L231 HydrophobicContact CB-CG 4.15Å; L193-L231 HydrophobicContact CD2-CD2 3.81Å; L193-L231 HydrophobicContact CG-CD2 3.74Å; L196-L231 HydrophobicContact CD1-CD1 4.3Å; L223-L231 HydrophobicContact CD1-CD1 4.21Å; L223-L231 HydrophobicContact CD2-CD1 3.83Å; L227-L231 WeakPolarHBondContact O-CB 3.42Å; L227-L231 WeakPolarHBondContact O-CG 3.41Å; L227-L231 PolarHBondContact O-N 2.9Å; E228-L231 PolarHBondContact O-N 3.16Å; T229-L231 VanDerWaalsContact C-N 3.33Å; T229-L231 PolarHBondContact O-N 3.3Å; L231-L266 HydrophobicContact CB-CD2 3.91Å; L231-L266 HydrophobicContact CD1-CD2 3.99Å; L231-L266 HydrophobicContact CD2-CD2 4.37Å; L231-L266 HydrophobicContact CG-CD2 4.32Å
232Q92.4Very high88.4Confident82 Ų8240.3 Ų40.338%0.38321%0.207SC..Hα-helixtrans-100.2-34.2-169.5-64.1178.313.700114.8E228 T229 A234 H235 V236 L266E228-Q232 WeakPolarHBondContact O-CB 3.19Å; E228-Q232 PolarHBondContact O-N 3.07Å; T229-Q232 PolarHBondContact O-N 2.88Å; Q232-A234 VanDerWaalsContact C-N 3.33Å; Q232-A234 PolarHBondContact O-N 2.99Å; Q232-H235 VanDerWaalsContact CA-NE2 3.35Å; Q232-H235 WeakPolarHBondContact CA-NE2 3.35Å; Q232-H235 PolarHBondContact O-CD2 2.95Å; Q232-H235 PolarHBondContact O-CE1 3.42Å; Q232-H235 PolarHBondContact O-ND1 3.29Å; Q232-H235 PolarHBondContact O-NE2 3.04Å; Q232-V236 WeakPolarHBondContact O-CG2 3.46Å; Q232-V236 PolarHBondContact O-N 3.35Å; Q232-L266 HydrophobicContact CG-CD1 3.8Å
233R92.4Very high88.8Confident44 Ų4433 Ų3317%0.16617%0.174CC..Hα-helixtrans-66.2-33.4-165.1-171.557.4168.7-166.8-3.9113.3E153 Y185 T229 V236 I237E153-R233 IonicContact OE1-CZ 3.81Å; E153-R233 IonicContact OE1-NE 3.34Å; E153-R233 PolarHBondContact OE1-NE 2.95Å; E153-R233 IonicContact OE1-NH2 3.24Å; E153-R233 PolarHBondContact OE1-NH2 3.27Å; E153-R233 IonicContact OE2-CZ 3.12Å; E153-R233 IonicContact OE2-NE 3.21Å; E153-R233 IonicContact OE2-NH2 3.47Å; E153-R233 PolarHBondContact OE2-NH2 3.35Å; Y185-R233 HydrophobicContact CD1-CB 3.9Å; Y185-R233 HydrophobicContact CD1-CG 4.11Å; Y185-R233 HydrophobicContact CD2-CB 4.03Å; Y185-R233 HydrophobicContact CD2-CG 3.62Å; Y185-R233 HydrophobicContact CE1-CB 4.05Å; Y185-R233 HydrophobicContact CE1-CG 3.88Å; Y185-R233 HydrophobicContact CE2-CB 4.14Å; Y185-R233 HydrophobicContact CE2-CG 3.32Å; Y185-R233 HydrophobicContact CG-CB 3.89Å; Y185-R233 HydrophobicContact CG-CG 3.99Å; Y185-R233 VanDerWaalsContact CZ-CG 3.45Å; T229-R233 HydrophobicContact CG2-CB 4.02Å; T229-R233 HydrophobicContact CG2-CG 4.44Å; T229-R233 WeakPolarHBondContact O-CB 3.29Å; T229-R233 PolarHBondContact O-N 2.8Å; R233-V236 PolarHBondContact O-N 3.15Å; R233-I237 HydrophobicContact CG-CD1 3.94Å; R233-I237 HydrophobicContact CG-CG1 4.41Å; R233-I237 WeakPolarHBondContact O-CG1 3.46Å; R233-I237 PolarHBondContact O-N 3.04Å
234A91.4Very high88.8Confident0 Ų033.6 Ų33.60%018%0.177CC..Hα-helixtrans-57.9-55.8179.900000112.5E186 Q232 V236 I237 H238E186-A234 HydrophobicContact CG-CB 3.86Å; Q232-A234 VanDerWaalsContact C-N 3.33Å; Q232-A234 PolarHBondContact O-N 2.99Å; A234-V236 VanDerWaalsContact C-N 3.33Å; A234-V236 PolarHBondContact O-N 3.36Å; A234-I237 PolarHBondContact O-N 3.44Å; A234-H238 PolarHBondContact O-CD2 3.25Å; A234-H238 VanDerWaalsContact O-CD2 3.22Å; A234-H238 PolarHBondContact O-N 2.97Å; A234-H238 VanDerWaalsContact O-N 3.1Å
235H90.9Very high88.8Confident8 Ų832.6 Ų32.64%0.03716%0.164CC..Hα-helixtrans-69-32-179.461.370.7000112.1Q232 I237 H238 F239 R250 F251Q232-H235 VanDerWaalsContact CA-NE2 3.35Å; Q232-H235 WeakPolarHBondContact CA-NE2 3.35Å; Q232-H235 PolarHBondContact O-CD2 2.95Å; Q232-H235 PolarHBondContact O-CE1 3.42Å; Q232-H235 PolarHBondContact O-ND1 3.29Å; Q232-H235 PolarHBondContact O-NE2 3.04Å; H235-I237 VanDerWaalsContact C-N 3.32Å; H235-I237 PolarHBondContact O-N 3.26Å; H235-H238 PolarHBondContact O-N 3.35Å; H235-F239 HydrophobicContact CB-CD2 4.49Å; H235-F239 HydrophobicContact CB-CE2 4.13Å; H235-F239 WeakPolarHBondContact O-CD2 3.32Å; H235-F239 PolarHBondContact O-N 3.19Å; H235-R250 HydrophobicContact CB-CB 3.93Å; H235-F251 HydrophobicContact CB-CD1 4.12Å; H235-F251 HydrophobicContact CB-CE1 4.06Å; H235-F251 AromaticContact CD2-CD1 3.97Å; H235-F251 AromaticContact CD2-CE1 3.79Å; H235-F251 AromaticContact CE1-CE1 3.61Å; H235-F251 AromaticContact CG-CD1 3.88Å; H235-F251 AromaticContact CG-CE1 3.52Å; H235-F251 AromaticContact ND1-CE1 3.39Å; H235-F251 WeakPolarHBondContact ND1-CE1 3.43Å; H235-F251 AromaticContact NE2-CE1 3.82Å
236V91.7Very high88.6Confident48 Ų4832.7 Ų32.729%0.29116%0.164SC..Hα-helixtrans-60.1-42.1173.9170.90000111.3Q232 R233 A234 K240Q232-V236 WeakPolarHBondContact O-CG2 3.46Å; Q232-V236 PolarHBondContact O-N 3.35Å; R233-V236 PolarHBondContact O-N 3.15Å; A234-V236 VanDerWaalsContact C-N 3.33Å; A234-V236 PolarHBondContact O-N 3.36Å; V236-K240 HydrophobicContact CG1-CD 4.3Å; V236-K240 WeakPolarHBondContact O-CB 3.45Å; V236-K240 VanDerWaalsContact O-CG 3.31Å; V236-K240 WeakPolarHBondContact O-CG 3.36Å; V236-K240 PolarHBondContact O-N 3.33Å
237I89.1Confident88.5Confident19 Ų1932.4 Ų32.410%0.09716%0.163CC..Hα-helixtrans-67.9-44.3176.6-65.6167.7000110.6I181 I182 Y185 R233 A234 H235 F239 K240 N241I181-I237 HydrophobicContact CG2-CD1 4.08Å; I182-I237 HydrophobicContact CD1-CG2 3.78Å; I182-I237 HydrophobicContact CG1-CB 4.27Å; I182-I237 HydrophobicContact CG1-CD1 4.48Å; I182-I237 HydrophobicContact CG1-CG2 3.68Å; Y185-I237 HydrophobicContact CD2-CD1 3.84Å; Y185-I237 HydrophobicContact CE2-CD1 3.76Å; R233-I237 HydrophobicContact CG-CD1 3.94Å; R233-I237 HydrophobicContact CG-CG1 4.41Å; R233-I237 WeakPolarHBondContact O-CG1 3.46Å; R233-I237 PolarHBondContact O-N 3.04Å; A234-I237 PolarHBondContact O-N 3.44Å; H235-I237 VanDerWaalsContact C-N 3.32Å; H235-I237 PolarHBondContact O-N 3.26Å; I237-F239 VanDerWaalsContact C-N 3.33Å; I237-F239 PolarHBondContact O-N 3.35Å; I237-K240 PolarHBondContact O-N 3.47Å; I237-K240 VanDerWaalsContact O-N 3.16Å; I237-N241 WeakPolarHBondContact O-CB 3.02Å; I237-N241 VanDerWaalsContact O-CG 3.28Å; I237-N241 PolarHBondContact O-N 3Å; I237-N241 PolarHBondContact O-OD1 3.38Å
238H86.8Confident88.5Confident2 Ų232.1 Ų32.11%0.00916%0.162CC..Hα-helixtrans-54.9-47.5177-73.6-52000112.1I182 E186 A234 H235 N241 G242 N243 R246I182-H238 VanDerWaalsContact CG2-CE1 3.45Å; I182-H238 WeakPolarHBondContact CG2-CE1 3.45Å; I182-H238 WeakPolarHBondContact CG2-NE2 3.42Å; E186-H238 IonicContact OE1-CD2 3.72Å; E186-H238 IonicContact OE1-CE1 3.12Å; E186-H238 IonicContact OE1-NE2 3.26Å; E186-H238 PolarHBondContact OE1-NE2 2.86Å; A234-H238 PolarHBondContact O-CD2 3.25Å; A234-H238 VanDerWaalsContact O-CD2 3.22Å; A234-H238 PolarHBondContact O-N 2.97Å; A234-H238 VanDerWaalsContact O-N 3.1Å; H235-H238 PolarHBondContact O-N 3.35Å; H238-N241 PolarHBondContact O-N 3.05Å; H238-G242 PolarHBondContact O-N 2.9Å; H238-N243 PolarHBondContact O-N 2.88Å; H238-R246 HydrophobicContact CB-CB 4.41Å
239F88.1Confident88.5Confident53 Ų5328.3 Ų28.323%0.23215%0.145CC..Hα-helixtrans-68.4-36.3177.4-66.5-54.6000113.4H235 I237 N241 G242 L244 F251 I277H235-F239 HydrophobicContact CB-CD2 4.49Å; H235-F239 HydrophobicContact CB-CE2 4.13Å; H235-F239 WeakPolarHBondContact O-CD2 3.32Å; H235-F239 PolarHBondContact O-N 3.19Å; I237-F239 VanDerWaalsContact C-N 3.33Å; I237-F239 PolarHBondContact O-N 3.35Å; F239-N241 PolarHBondContact O-N 2.86Å; F239-G242 PolarHBondContact O-N 3.25Å; F239-G242 VanDerWaalsContact O-N 3.15Å; F239-L244 HydrophobicContact CD1-CD1 4.08Å; F239-L244 HydrophobicContact CE1-CD1 4.46Å; F239-L244 HydrophobicContact CE1-CG 4.41Å; F239-F251 HydrophobicContact CD2-CZ 4.39Å; F239-F251 HydrophobicContact CE2-CD1 4.39Å; F239-F251 HydrophobicContact CE2-CD2 4.04Å; F239-F251 AromaticContact CE2-CE1 3.9Å; F239-F251 HydrophobicContact CE2-CE1 3.9Å; F239-F251 AromaticContact CE2-CE2 3.48Å; F239-F251 HydrophobicContact CE2-CE2 3.48Å; F239-F251 VanDerWaalsContact CE2-CE2 3.48Å; F239-F251 HydrophobicContact CE2-CG 4.49Å; F239-F251 AromaticContact CE2-CZ 3.43Å; F239-F251 HydrophobicContact CE2-CZ 3.43Å; F239-F251 VanDerWaalsContact CE2-CZ 3.43Å; F239-F251 AromaticContact CZ-CD2 3.84Å; F239-F251 HydrophobicContact CZ-CD2 3.84Å; F239-F251 AromaticContact CZ-CE2 3.59Å; F239-F251 HydrophobicContact CZ-CE2 3.59Å; F239-F251 HydrophobicContact CZ-CG 4.47Å; F239-F251 HydrophobicContact CZ-CZ 4.05Å; F239-I277 HydrophobicContact CD1-CD1 4.38Å; F239-I277 HydrophobicContact CE1-CD1 3.51Å; F239-I277 HydrophobicContact CE2-CD1 4.2Å; F239-I277 HydrophobicContact CZ-CD1 3.39Å
240K86.5Confident88.5Confident137 Ų13727.9 Ų27.960%0.59614%0.142SC*.Hα-helixtrans-62-34173.7-79.8-179.5177.1-172.10112.6V236 I237 G242V236-K240 HydrophobicContact CG1-CD 4.3Å; V236-K240 WeakPolarHBondContact O-CB 3.45Å; V236-K240 VanDerWaalsContact O-CG 3.31Å; V236-K240 WeakPolarHBondContact O-CG 3.36Å; V236-K240 PolarHBondContact O-N 3.33Å; I237-K240 PolarHBondContact O-N 3.47Å; I237-K240 VanDerWaalsContact O-N 3.16Å; K240-G242 PolarHBondContact O-N 3.15Å
241N82.4Confident88.6Confident40 Ų4028 Ų2821%0.21414%0.142CC..THydrogen-bonded Turntrans-84.42.9179.3-65-2.1000112.9I237 H238 F239 N243I237-N241 WeakPolarHBondContact O-CB 3.02Å; I237-N241 VanDerWaalsContact O-CG 3.28Å; I237-N241 PolarHBondContact O-N 3Å; I237-N241 PolarHBondContact O-OD1 3.38Å; H238-N241 PolarHBondContact O-N 3.05Å; F239-N241 PolarHBondContact O-N 2.86Å; N241-N243 PolarHBondContact O-N 3.25Å
242G78.9Confident88.7Confident34 Ų3428.5 Ų28.535%0.35114%0.144SC..THydrogen-bonded Turntrans69.812.7-176.700000114.4H238 F239 K240 L244H238-G242 PolarHBondContact O-N 2.9Å; F239-G242 PolarHBondContact O-N 3.25Å; F239-G242 VanDerWaalsContact O-N 3.15Å; K240-G242 PolarHBondContact O-N 3.15Å; G242-L244 PolarHBondContact O-N 3.01Å
243N82.8Confident88.7Confident21 Ų2126.4 Ų26.411%0.11213%0.134CC..  trans-87.882178.6-167.1-38.3000109.8H238 N241 T245 R246 G247H238-N243 PolarHBondContact O-N 2.88Å; N241-N243 PolarHBondContact O-N 3.25Å; N243-T245 PolarHBondContact OD1-OG1 3.47Å; N243-T245 VanDerWaalsContact OD1-OG1 3.06Å; N243-R246 WeakPolarHBondContact ND2-CD 3.49Å; N243-R246 VanDerWaalsContact OD1-CB 3.31Å; N243-R246 WeakPolarHBondContact OD1-CB 3.49Å; N243-R246 VanDerWaalsContact OD1-CG 3.28Å; N243-R246 WeakPolarHBondContact OD1-CG 3.34Å; N243-R246 PolarHBondContact OD1-N 2.59Å; N243-R246 VanDerWaalsContact OD1-N 3.12Å; N243-G247 PolarHBondContact O-N 3.46Å
244L83.9Confident88.8Confident42 Ų4224.4 Ų24.422%0.2213%0.127CC..Hα-helixtrans-68.4-37.2-173.2-119.270.8000111.6F239 G242 G247 V248 I277 L300 D301F239-L244 HydrophobicContact CD1-CD1 4.08Å; F239-L244 HydrophobicContact CE1-CD1 4.46Å; F239-L244 HydrophobicContact CE1-CG 4.41Å; G242-L244 PolarHBondContact O-N 3.01Å; L244-G247 PolarHBondContact O-N 2.68Å; L244-V248 WeakPolarHBondContact O-CB 3.43Å; L244-V248 VanDerWaalsContact O-CG2 3.3Å; L244-V248 WeakPolarHBondContact O-CG2 3.25Å; L244-V248 PolarHBondContact O-N 2.69Å; L244-I277 HydrophobicContact CD2-CG2 4.22Å; L244-L300 HydrophobicContact CB-CB 4.34Å; L244-D301 PolarHBondContact N-OD1 2.71Å
245T85.9Confident89Confident12 Ų1225.3 Ų25.37%0.07413%0.132CC..Hα-helixtrans-61.4-48.7-179.150.40000112.5N243 G249 W288 S298 D301N243-T245 PolarHBondContact OD1-OG1 3.47Å; N243-T245 VanDerWaalsContact OD1-OG1 3.06Å; T245-G249 PolarHBondContact O-N 3.31Å; T245-W288 HydrophobicContact CG2-CH2 4.28Å; T245-W288 HydrophobicContact CG2-CZ3 4.47Å; T245-S298 WeakPolarHBondContact CG2-OG 3.32Å; T245-D301 WeakPolarHBondContact CB-OD2 3.49Å; T245-D301 WeakPolarHBondContact CG2-OD2 3.3Å; T245-D301 PolarHBondContact OG1-OD2 2.72Å
246R85.5Confident89.2Confident34 Ų3429.4 Ų29.413%0.12815%0.147CC..Hα-helixtrans-68.9-36.7177.6-67.3-172.5-179.5-178-3.5112.2H238 N243 G249 R250 Y310H238-R246 HydrophobicContact CB-CB 4.41Å; N243-R246 WeakPolarHBondContact ND2-CD 3.49Å; N243-R246 VanDerWaalsContact OD1-CB 3.31Å; N243-R246 WeakPolarHBondContact OD1-CB 3.49Å; N243-R246 VanDerWaalsContact OD1-CG 3.28Å; N243-R246 WeakPolarHBondContact OD1-CG 3.34Å; N243-R246 PolarHBondContact OD1-N 2.59Å; N243-R246 VanDerWaalsContact OD1-N 3.12Å; R246-G249 PolarHBondContact O-N 3.48Å; R246-R250 WeakPolarHBondContact O-CG 3.32Å; R246-R250 PolarHBondContact O-N 3.27Å; R246-Y310 HydrophobicContact CG-CD2 4.19Å; R246-Y310 HydrophobicContact CG-CE2 4.46Å
247G89.6Confident89.4Confident0 Ų027.2 Ų27.20%013%0.134CC..Hα-helixtrans-60.4-50.2174.300000112.4N243 L244 R250 F251N243-G247 PolarHBondContact O-N 3.46Å; L244-G247 PolarHBondContact O-N 2.68Å; G247-R250 PolarHBondContact O-N 3.31Å; G247-F251 PolarHBondContact O-N 2.67Å
248V91.9Very high89.7Confident0 Ų028.7 Ų28.70%014%0.144CC..Hα-helixtrans-62.5-42.1175.9168.20000111.2L244 R250 F251 R252 L274 I277 M282 W288L244-V248 WeakPolarHBondContact O-CB 3.43Å; L244-V248 VanDerWaalsContact O-CG2 3.3Å; L244-V248 WeakPolarHBondContact O-CG2 3.25Å; L244-V248 PolarHBondContact O-N 2.69Å; V248-R250 VanDerWaalsContact C-N 3.35Å; V248-R250 PolarHBondContact O-N 3.19Å; V248-F251 WeakPolarHBondContact O-CB 3.41Å; V248-F251 PolarHBondContact O-N 3.28Å; V248-R252 HydrophobicContact CG1-CG 4.48Å; V248-R252 WeakPolarHBondContact O-CG 3.5Å; V248-R252 PolarHBondContact O-N 3.32Å; V248-L274 HydrophobicContact CB-CD1 4.37Å; V248-L274 HydrophobicContact CG1-CD1 3.85Å; V248-L274 HydrophobicContact CG2-CD1 4.1Å; V248-I277 HydrophobicContact CG2-CG2 3.85Å; V248-M282 HydrophobicContact CG2-SD 4.32Å; V248-W288 HydrophobicContact CB-CH2 3.9Å; V248-W288 HydrophobicContact CB-CZ2 4.17Å; V248-W288 HydrophobicContact CG1-CH2 3.65Å; V248-W288 HydrophobicContact CG1-CZ2 3.7Å
249G90.9Very high90Very high4 Ų431 Ų314%0.04116%0.155CC..Hα-helixtrans-55.5-47.8173.900000112.1T245 R246 F251 R252 E253T245-G249 PolarHBondContact O-N 3.31Å; R246-G249 PolarHBondContact O-N 3.48Å; G249-F251 PolarHBondContact O-N 3Å; G249-R252 PolarHBondContact O-N 3.03Å; G249-E253 VanDerWaalsContact O-CG 3.31Å; G249-E253 WeakPolarHBondContact O-CG 3.42Å; G249-E253 PolarHBondContact O-N 3.3Å
250R91.9Very high90.1Very high4 Ų428.7 Ų28.72%0.01515%0.145CC..Hα-helixtrans-63.5-39.3176.2-72.6-55.6-58.2178.5-6113D190 H235 R246 G247 V248 E253 I254D190-R250 IonicContact OD1-CZ 2.59Å; D190-R250 VanDerWaalsContact OD1-CZ 3.3Å; D190-R250 IonicContact OD1-NH1 2.94Å; D190-R250 PolarHBondContact OD1-NH1 3.44Å; D190-R250 IonicContact OD1-NH2 3.57Å; D190-R250 PolarHBondContact OD1-NH2 3.43Å; D190-R250 IonicContact OD2-NH1 3.99Å; H235-R250 HydrophobicContact CB-CB 3.93Å; R246-R250 WeakPolarHBondContact O-CG 3.32Å; R246-R250 PolarHBondContact O-N 3.27Å; G247-R250 PolarHBondContact O-N 3.31Å; V248-R250 VanDerWaalsContact C-N 3.35Å; V248-R250 PolarHBondContact O-N 3.19Å; R250-E253 IonicContact CZ-OE2 3.61Å; R250-E253 IonicContact NE-OE2 3.37Å; R250-E253 IonicContact NH1-OE2 3.59Å; R250-E253 PolarHBondContact NH1-OE2 3.24Å; R250-E253 PolarHBondContact O-N 2.93Å; R250-I254 WeakPolarHBondContact O-CG1 3.35Å; R250-I254 PolarHBondContact O-N 3.36Å; R250-I254 VanDerWaalsContact O-N 3.11Å
251F95.1Very high90.2Very high3 Ų329.9 Ų29.91%0.01315%0.145CC..Hα-helixtrans-60-47.8172.8-78.6-11.3000112.3H235 F239 G247 V248 G249 E253 I254 L255 I270 Q273 L274 I277H235-F251 HydrophobicContact CB-CD1 4.12Å; H235-F251 HydrophobicContact CB-CE1 4.06Å; H235-F251 AromaticContact CD2-CD1 3.97Å; H235-F251 AromaticContact CD2-CE1 3.79Å; H235-F251 AromaticContact CE1-CE1 3.61Å; H235-F251 AromaticContact CG-CD1 3.88Å; H235-F251 AromaticContact CG-CE1 3.52Å; H235-F251 AromaticContact ND1-CE1 3.39Å; H235-F251 WeakPolarHBondContact ND1-CE1 3.43Å; H235-F251 AromaticContact NE2-CE1 3.82Å; F239-F251 HydrophobicContact CD2-CZ 4.39Å; F239-F251 HydrophobicContact CE2-CD1 4.39Å; F239-F251 HydrophobicContact CE2-CD2 4.04Å; F239-F251 AromaticContact CE2-CE1 3.9Å; F239-F251 HydrophobicContact CE2-CE1 3.9Å; F239-F251 AromaticContact CE2-CE2 3.48Å; F239-F251 HydrophobicContact CE2-CE2 3.48Å; F239-F251 VanDerWaalsContact CE2-CE2 3.48Å; F239-F251 HydrophobicContact CE2-CG 4.49Å; F239-F251 AromaticContact CE2-CZ 3.43Å; F239-F251 HydrophobicContact CE2-CZ 3.43Å; F239-F251 VanDerWaalsContact CE2-CZ 3.43Å; F239-F251 AromaticContact CZ-CD2 3.84Å; F239-F251 HydrophobicContact CZ-CD2 3.84Å; F239-F251 AromaticContact CZ-CE2 3.59Å; F239-F251 HydrophobicContact CZ-CE2 3.59Å; F239-F251 HydrophobicContact CZ-CG 4.47Å; F239-F251 HydrophobicContact CZ-CZ 4.05Å; G247-F251 PolarHBondContact O-N 2.67Å; V248-F251 WeakPolarHBondContact O-CB 3.41Å; V248-F251 PolarHBondContact O-N 3.28Å; G249-F251 PolarHBondContact O-N 3Å; F251-E253 PolarHBondContact O-N 3.46Å; F251-I254 PolarHBondContact O-N 3.34Å; F251-L255 WeakPolarHBondContact O-CB 3.41Å; F251-L255 WeakPolarHBondContact O-CG 3.46Å; F251-L255 PolarHBondContact O-N 2.97Å; F251-I270 HydrophobicContact CB-CG2 3.86Å; F251-I270 HydrophobicContact CD1-CB 4.47Å; F251-I270 HydrophobicContact CD1-CD1 4.42Å; F251-I270 HydrophobicContact CD1-CG1 4.3Å; F251-I270 HydrophobicContact CD1-CG2 3.51Å; F251-I270 HydrophobicContact CD2-CG2 4.39Å; F251-I270 HydrophobicContact CE1-CD1 4.47Å; F251-I270 HydrophobicContact CE1-CG1 4.07Å; F251-I270 HydrophobicContact CE1-CG2 3.97Å; F251-I270 HydrophobicContact CG-CG2 3.71Å; F251-Q273 HydrophobicContact CE2-CB 3.83Å; F251-Q273 HydrophobicContact CZ-CB 3.92Å; F251-L274 HydrophobicContact CB-CB 4.32Å; F251-L274 HydrophobicContact CB-CD1 4.33Å; F251-L274 HydrophobicContact CB-CD2 4.12Å; F251-L274 HydrophobicContact CB-CG 4.49Å; F251-L274 HydrophobicContact CD2-CB 3.78Å; F251-L274 HydrophobicContact CD2-CD1 4.13Å; F251-L274 HydrophobicContact CD2-CG 4.46Å; F251-L274 HydrophobicContact CE2-CB 4.48Å; F251-L274 HydrophobicContact CG-CB 4.45Å; F251-I277 HydrophobicContact CD2-CD1 4.13Å; F251-I277 HydrophobicContact CE2-CD1 3.69Å
252R94.9Very high90.4Very high11 Ų1129.7 Ų29.74%0.04215%0.146CC..Hα-helixtrans-61.7-42.3177.5-73.2174.4170.1177.82.2111.9V248 G249 I254 L255 R256 L274 W288 E337V248-R252 HydrophobicContact CG1-CG 4.48Å; V248-R252 WeakPolarHBondContact O-CG 3.5Å; V248-R252 PolarHBondContact O-N 3.32Å; G249-R252 PolarHBondContact O-N 3.03Å; R252-I254 PolarHBondContact O-N 3.5Å; R252-L255 PolarHBondContact O-N 2.85Å; R252-R256 WeakPolarHBondContact O-CB 3.48Å; R252-R256 WeakPolarHBondContact O-CG 3.34Å; R252-R256 PolarHBondContact O-N 3.19Å; R252-L274 HydrophobicContact CG-CD2 3.99Å; R252-W288 VanDerWaalsContact CZ-O 3.24Å; R252-W288 PolarHBondContact NH1-O 3.17Å; R252-W288 PolarHBondContact NH2-O 2.83Å; R252-E337 IonicContact CZ-OE1 3.84Å; R252-E337 IonicContact CZ-OE2 3.89Å; R252-E337 IonicContact NE-OE1 2.88Å; R252-E337 PolarHBondContact NE-OE1 3.48Å; R252-E337 IonicContact NE-OE2 2.87Å; R252-E337 IonicContact NH2-OE1 2.76Å; R252-E337 IonicContact NH2-OE2 3.28Å; R252-E337 PolarHBondContact NH2-OE2 3.01Å
253E92.7Very high91Very high38 Ų3828.3 Ų28.318%0.17813%0.131CC..Hα-helixtrans-59.1-46.4176.9-74.7175.4-161.700112.4G249 R250 F251 A257 Y310 K312G249-E253 VanDerWaalsContact O-CG 3.31Å; G249-E253 WeakPolarHBondContact O-CG 3.42Å; G249-E253 PolarHBondContact O-N 3.3Å; R250-E253 IonicContact CZ-OE2 3.61Å; R250-E253 IonicContact NE-OE2 3.37Å; R250-E253 IonicContact NH1-OE2 3.59Å; R250-E253 PolarHBondContact NH1-OE2 3.24Å; R250-E253 PolarHBondContact O-N 2.93Å; F251-E253 PolarHBondContact O-N 3.46Å; E253-A257 PolarHBondContact O-N 3.24Å; E253-Y310 PolarHBondContact OE1-OH 2.8Å; E253-K312 VanDerWaalsContact CD-NZ 3.3Å; E253-K312 WeakPolarHBondContact OE1-CE 3.3Å; E253-K312 IonicContact OE1-NZ 3.07Å; E253-K312 PolarHBondContact OE1-NZ 3.06Å; E253-K312 WeakPolarHBondContact OE2-CE 3.18Å; E253-K312 IonicContact OE2-NZ 3.53Å; E253-K312 PolarHBondContact OE2-NZ 2.89Å
254I94.4Very high91.3Very high3 Ų330.2 Ų30.22%0.01514%0.139CC..Hα-helixtrans-65.3-42.4178.1-65.2165.6000110.9L193 R250 F251 R252 A257 L266 I270L193-I254 HydrophobicContact CD1-CG1 4.41Å; R250-I254 WeakPolarHBondContact O-CG1 3.35Å; R250-I254 PolarHBondContact O-N 3.36Å; R250-I254 VanDerWaalsContact O-N 3.11Å; F251-I254 PolarHBondContact O-N 3.34Å; R252-I254 PolarHBondContact O-N 3.5Å; I254-A257 PolarHBondContact O-N 3.48Å; I254-L266 HydrophobicContact CG2-CD2 4.38Å; I254-I270 HydrophobicContact CB-CD1 4.35Å; I254-I270 HydrophobicContact CD1-CD1 3.83Å; I254-I270 HydrophobicContact CG2-CD1 3.86Å
255L95.9Very high91.5Very high19 Ų1933.2 Ų33.210%0.09916%0.155CC..Hα-helixtrans-71.2-32.3-178.1-73.6169.7000113.5F251 R252 R267 I270 A271 L274 L341F251-L255 WeakPolarHBondContact O-CB 3.41Å; F251-L255 WeakPolarHBondContact O-CG 3.46Å; F251-L255 PolarHBondContact O-N 2.97Å; R252-L255 PolarHBondContact O-N 2.85Å; L255-R267 HydrophobicContact CD2-CB 4.11Å; L255-R267 HydrophobicContact CD2-CG 4.36Å; L255-R267 WeakPolarHBondContact CD2-O 3.41Å; L255-R267 PolarHBondContact O-NH2 3.49Å; L255-I270 HydrophobicContact CD1-CG2 3.93Å; L255-I270 HydrophobicContact CD2-CG2 4.27Å; L255-I270 HydrophobicContact CG-CG2 3.88Å; L255-A271 HydrophobicContact CD1-CB 4.47Å; L255-A271 HydrophobicContact CD2-CB 3.96Å; L255-L274 HydrophobicContact CD1-CD2 3.74Å; L255-L341 HydrophobicContact CD1-CD2 3.6Å
256R95.1Very high91.7Very high93 Ų9333.3 Ų33.335%0.35116%0.155SC..Hα-helixtrans-73.4-25.3176.5-77.9-178.766-165.9-5.8112.7R252 P290 L291 V322 Y323R252-R256 WeakPolarHBondContact O-CB 3.48Å; R252-R256 WeakPolarHBondContact O-CG 3.34Å; R252-R256 PolarHBondContact O-N 3.19Å; R256-P290 PolarHBondContact NH1-O 2.9Å; R256-L291 VanDerWaalsContact CZ-CD2 3.44Å; R256-L291 VanDerWaalsContact NH2-CD2 3.31Å; R256-V322 HydrophobicContact CB-CG1 3.92Å; R256-V322 CarbonylContact O-C 3.26Å; R256-V322 VanDerWaalsContact O-CA 3.29Å; R256-V322 WeakPolarHBondContact O-CA 3.39Å; R256-V322 WeakPolarHBondContact O-CG1 3.09Å; R256-Y323 VanDerWaalsContact O-CD2 3.24Å; R256-Y323 WeakPolarHBondContact O-CD2 3.44Å; R256-Y323 PolarHBondContact O-N 2.88Å
257A95.3Very high92Very high2 Ų232.4 Ų32.42%0.01715%0.151CC..BIsolated β-bridgetrans-60.4138.8172.200000110.7L193 E253 I254 E259 R321 Y323L193-A257 HydrophobicContact CD1-CB 3.93Å; L193-A257 HydrophobicContact CD2-CB 4.38Å; E253-A257 PolarHBondContact O-N 3.24Å; I254-A257 PolarHBondContact O-N 3.48Å; A257-E259 PolarHBondContact O-N 2.99Å; A257-R321 WeakPolarHBondContact CA-O 3.48Å; A257-Y323 WeakPolarHBondContact O-CE2 3.41Å
258V94.8Very high92.1Very high51 Ų5133.6 Ų33.631%0.30916%0.158SC..PPolyproline II helixtrans-57.6132.9178.5176.70000109.5Q197 R321 Y323Q197-V258 PolarHBondContact NE2-O 2.93Å; V258-R321 HydrophobicContact CB-CB 4.49Å; V258-R321 HydrophobicContact CG2-CB 4.04Å; V258-R321 PolarHBondContact N-O 3.37Å; V258-Y323 HydrophobicContact CG1-CE1 4.43Å; V258-Y323 HydrophobicContact CG2-CD1 4.31Å; V258-Y323 HydrophobicContact CG2-CE1 4.36Å
259E93.3Very high92Very high51 Ų5135.7 Ų35.724%0.23817%0.17CC..PPolyproline II helixtrans-62.4143.5-176.4-173.9177.9145.400111.8A257 Q264 R267 Y323A257-E259 PolarHBondContact O-N 2.99Å; E259-Q264 HydrophobicContact CG-CG 4.1Å; E259-Q264 WeakPolarHBondContact OE1-CG 3.37Å; E259-Q264 PolarHBondContact OE1-NE2 3.05Å; E259-R267 VanDerWaalsContact CD-NH1 3.33Å; E259-R267 VanDerWaalsContact CG-NH1 3.35Å; E259-R267 IonicContact OE2-CZ 3.13Å; E259-R267 IonicContact OE2-NH1 2.98Å; E259-R267 PolarHBondContact OE2-NH1 3.45Å; E259-Y323 WeakPolarHBondContact CB-OH 3.45Å; E259-Y323 PolarHBondContact N-OH 3.29Å
260T91.1Very high92.2Very high4 Ų435.5 Ų35.53%0.02517%0.168CC..  trans-128.7155.4169.163.90000108.2L196 Q197 E200 T262 T263 Q264L196-T260 HydrophobicContact CB-CG2 4.35Å; Q197-T260 HydrophobicContact CB-CG2 4.3Å; Q197-T260 HydrophobicContact CG-CG2 3.67Å; E200-T260 VanDerWaalsContact OE2-CA 3.31Å; E200-T260 WeakPolarHBondContact OE2-CA 3.41Å; E200-T260 WeakPolarHBondContact OE2-CB 3.25Å; E200-T260 WeakPolarHBondContact OE2-CG2 3.5Å; T260-T262 PolarHBondContact O-N 3.25Å; T260-T262 VanDerWaalsContact O-N 3.14Å; T260-T262 PolarHBondContact OG1-OG1 3.46Å; T260-T262 VanDerWaalsContact OG1-OG1 3.12Å; T260-T263 PolarHBondContact N-OG1 2.73Å; T260-T263 VanDerWaalsContact N-OG1 3.1Å; T260-T263 PolarHBondContact O-N 3.27Å; T260-T263 PolarHBondContact O-OG1 3.26Å; T260-T263 VanDerWaalsContact O-OG1 3.11Å; T260-T263 VanDerWaalsContact OG1-CG2 3.28Å; T260-T263 WeakPolarHBondContact OG1-CG2 3.22Å; T260-T263 PolarHBondContact OG1-N 3.05Å; T260-T263 PolarHBondContact OG1-OG1 2.91Å; T260-Q264 PolarHBondContact O-N 3.18Å
261R88.3Confident92.4Very high161 Ų16135.3 Ų35.361%0.60817%0.168SC*.G310 helixtrans-50.6-40.4177.3-71.9170.1-167.6-164.22.2113E200 T263E200-R261 VanDerWaalsContact OE1-CG 3.28Å; E200-R261 WeakPolarHBondContact OE1-CG 3.49Å; E200-R261 PolarHBondContact OE1-N 3.05Å; E200-R261 IonicContact OE1-NE 3.85Å; R261-T263 VanDerWaalsContact C-N 3.33Å; R261-T263 PolarHBondContact O-N 3.02Å
262T87.1Confident92.4Very high37 Ų3737.9 Ų37.923%0.22718%0.177CC..G310 helixtrans-72.4-21.6-178.851.50000114.3L221 T260L221-T262 HydrophobicContact CB-CG2 3.87Å; L221-T262 HydrophobicContact CD2-CG2 4.17Å; L221-T262 HydrophobicContact CG-CG2 4.26Å; L221-T262 WeakPolarHBondContact O-CG2 3.23Å; T260-T262 PolarHBondContact O-N 3.25Å; T260-T262 VanDerWaalsContact O-N 3.14Å; T260-T262 PolarHBondContact OG1-OG1 3.46Å; T260-T262 VanDerWaalsContact OG1-OG1 3.12Å
263T90.8Very high92.4Very high5 Ų540.8 Ų40.83%0.03119%0.191CC..G310 helixtrans-95.9-2-179.5580000113.6L193 L196 T260 R261 N265 L266 R267L193-T263 HydrophobicContact CD2-CG2 4.13Å; L196-T263 HydrophobicContact CD1-CG2 3.59Å; T260-T263 PolarHBondContact N-OG1 2.73Å; T260-T263 VanDerWaalsContact N-OG1 3.1Å; T260-T263 PolarHBondContact O-N 3.27Å; T260-T263 PolarHBondContact O-OG1 3.26Å; T260-T263 VanDerWaalsContact O-OG1 3.11Å; T260-T263 VanDerWaalsContact OG1-CG2 3.28Å; T260-T263 WeakPolarHBondContact OG1-CG2 3.22Å; T260-T263 PolarHBondContact OG1-N 3.05Å; T260-T263 PolarHBondContact OG1-OG1 2.91Å; R261-T263 VanDerWaalsContact C-N 3.33Å; R261-T263 PolarHBondContact O-N 3.02Å; T263-N265 PolarHBondContact O-N 3.36Å; T263-L266 PolarHBondContact O-N 3.25Å; T263-R267 WeakPolarHBondContact O-CB 3.3Å; T263-R267 VanDerWaalsContact O-CG 3.28Å; T263-R267 WeakPolarHBondContact O-CG 3.43Å; T263-R267 PolarHBondContact O-N 3.09Å
264Q89.2Confident92.5Very high61 Ų6139 Ų3929%0.28518%0.183SC..Hα-helixtrans-58.6-52.1-174.9-70.7-177-28.500113E259 T260 L266 R267 M268E259-Q264 HydrophobicContact CG-CG 4.1Å; E259-Q264 WeakPolarHBondContact OE1-CG 3.37Å; E259-Q264 PolarHBondContact OE1-NE2 3.05Å; T260-Q264 PolarHBondContact O-N 3.18Å; Q264-L266 VanDerWaalsContact C-N 3.35Å; Q264-L266 PolarHBondContact O-N 2.93Å; Q264-R267 PolarHBondContact O-N 3.2Å; Q264-M268 PolarHBondContact O-N 3.45Å
265N87.4Confident92.6Very high104 Ų10438.9 Ų38.956%0.55618%0.182SC*.Hα-helixtrans-63.9-39.9-179.7-170.517.4000112.2T263 M268 T269T263-N265 PolarHBondContact O-N 3.36Å; N265-M268 PolarHBondContact O-N 3.09Å; N265-M268 WeakPolarHBondContact OD1-CE 3.47Å; N265-T269 WeakPolarHBondContact O-CG2 3.4Å; N265-T269 PolarHBondContact O-N 3.43Å; N265-T269 PolarHBondContact O-OG1 2.94Å
266L90.3Very high92.6Very high15 Ų1539.3 Ų39.38%0.07918%0.184CC..Hα-helixtrans-61.7-45.3174.4-179.363.8000111.4L231 Q232 I254 T263 Q264 T269 I270L231-L266 HydrophobicContact CB-CD2 3.91Å; L231-L266 HydrophobicContact CD1-CD2 3.99Å; L231-L266 HydrophobicContact CD2-CD2 4.37Å; L231-L266 HydrophobicContact CG-CD2 4.32Å; Q232-L266 HydrophobicContact CG-CD1 3.8Å; I254-L266 HydrophobicContact CG2-CD2 4.38Å; T263-L266 PolarHBondContact O-N 3.25Å; Q264-L266 VanDerWaalsContact C-N 3.35Å; Q264-L266 PolarHBondContact O-N 2.93Å; L266-T269 PolarHBondContact O-N 2.98Å; L266-T269 PolarHBondContact O-OG1 2.67Å; L266-I270 HydrophobicContact CD1-CD1 3.59Å; L266-I270 HydrophobicContact CD1-CG1 4.03Å; L266-I270 HydrophobicContact CD2-CD1 4.36Å; L266-I270 HydrophobicContact CG-CD1 3.73Å; L266-I270 HydrophobicContact CG-CG1 4.4Å; L266-I270 WeakPolarHBondContact O-CB 3.48Å; L266-I270 WeakPolarHBondContact O-CG1 3.28Å; L266-I270 PolarHBondContact O-N 2.93Å
267R92.9Very high92.5Very high14 Ų1436 Ų365%0.05317%0.173CC..Hα-helixtrans-67-39.1179.6-71.2177.777.3-1182111.8L255 E259 T263 Q264 A271L255-R267 HydrophobicContact CD2-CB 4.11Å; L255-R267 HydrophobicContact CD2-CG 4.36Å; L255-R267 WeakPolarHBondContact CD2-O 3.41Å; L255-R267 PolarHBondContact O-NH2 3.49Å; E259-R267 VanDerWaalsContact CD-NH1 3.33Å; E259-R267 VanDerWaalsContact CG-NH1 3.35Å; E259-R267 IonicContact OE2-CZ 3.13Å; E259-R267 IonicContact OE2-NH1 2.98Å; E259-R267 PolarHBondContact OE2-NH1 3.45Å; T263-R267 WeakPolarHBondContact O-CB 3.3Å; T263-R267 VanDerWaalsContact O-CG 3.28Å; T263-R267 WeakPolarHBondContact O-CG 3.43Å; T263-R267 PolarHBondContact O-N 3.09Å; Q264-R267 PolarHBondContact O-N 3.2Å; R267-A271 WeakPolarHBondContact O-CB 3.45Å; R267-A271 PolarHBondContact O-N 3.17Å
268M90.7Very high92.4Very high26 Ų2636 Ų3613%0.12817%0.173CC..Hα-helixtrans-57.8-51.4173.8-177.7-178.469.500111.2Q264 N265 A271 R272 S345 M348 A349Q264-M268 PolarHBondContact O-N 3.45Å; N265-M268 PolarHBondContact O-N 3.09Å; N265-M268 WeakPolarHBondContact OD1-CE 3.47Å; M268-A271 PolarHBondContact O-N 3.25Å; M268-R272 PolarHBondContact O-N 3.11Å; M268-R272 VanDerWaalsContact O-N 3.15Å; M268-S345 PolarHBondContact O-OG 3.02Å; M268-M348 HydrophobicContact CB-CB 4.07Å; M268-M348 HydrophobicContact CB-SD 3.85Å; M268-M348 HydrophobicContact CG-CB 3.96Å; M268-M348 HydrophobicContact SD-CB 3.95Å; M268-A349 HydrophobicContact SD-CB 3.98Å
269T90.5Very high92.4Very high43 Ų4334 Ų3426%0.26416%0.16SC..Hα-helixtrans-66.8-43.5-178.450.50000112.8N265 L266 R272 Q273N265-T269 WeakPolarHBondContact O-CG2 3.4Å; N265-T269 PolarHBondContact O-N 3.43Å; N265-T269 PolarHBondContact O-OG1 2.94Å; L266-T269 PolarHBondContact O-N 2.98Å; L266-T269 PolarHBondContact O-OG1 2.67Å; T269-R272 PolarHBondContact O-N 3.45Å; T269-Q273 WeakPolarHBondContact O-CG 3.29Å; T269-Q273 PolarHBondContact O-N 3.43Å
270I94.6Very high92.2Very high1 Ų140.7 Ų40.71%0.00518%0.183CC..Hα-helixtrans-65.6-41.1176.6-71.2178.7000111.3F251 I254 L255 L266 R272 Q273 L274F251-I270 HydrophobicContact CB-CG2 3.86Å; F251-I270 HydrophobicContact CD1-CB 4.47Å; F251-I270 HydrophobicContact CD1-CD1 4.42Å; F251-I270 HydrophobicContact CD1-CG1 4.3Å; F251-I270 HydrophobicContact CD1-CG2 3.51Å; F251-I270 HydrophobicContact CD2-CG2 4.39Å; F251-I270 HydrophobicContact CE1-CD1 4.47Å; F251-I270 HydrophobicContact CE1-CG1 4.07Å; F251-I270 HydrophobicContact CE1-CG2 3.97Å; F251-I270 HydrophobicContact CG-CG2 3.71Å; I254-I270 HydrophobicContact CB-CD1 4.35Å; I254-I270 HydrophobicContact CD1-CD1 3.83Å; I254-I270 HydrophobicContact CG2-CD1 3.86Å; L255-I270 HydrophobicContact CD1-CG2 3.93Å; L255-I270 HydrophobicContact CD2-CG2 4.27Å; L255-I270 HydrophobicContact CG-CG2 3.88Å; L266-I270 HydrophobicContact CD1-CD1 3.59Å; L266-I270 HydrophobicContact CD1-CG1 4.03Å; L266-I270 HydrophobicContact CD2-CD1 4.36Å; L266-I270 HydrophobicContact CG-CD1 3.73Å; L266-I270 HydrophobicContact CG-CG1 4.4Å; L266-I270 WeakPolarHBondContact O-CB 3.48Å; L266-I270 WeakPolarHBondContact O-CG1 3.28Å; L266-I270 PolarHBondContact O-N 2.93Å; I270-R272 VanDerWaalsContact C-N 3.35Å; I270-R272 PolarHBondContact O-N 3.19Å; I270-Q273 PolarHBondContact O-N 3.33Å; I270-L274 WeakPolarHBondContact O-CB 3.37Å; I270-L274 PolarHBondContact O-N 2.93Å
271A95.7Very high92Very high0 Ų042.2 Ų42.20%020%0.199CC..Hα-helixtrans-59.1-47.1177.700000111.2L255 R267 M268 L274 A275 L341L255-A271 HydrophobicContact CD1-CB 4.47Å; L255-A271 HydrophobicContact CD2-CB 3.96Å; R267-A271 WeakPolarHBondContact O-CB 3.45Å; R267-A271 PolarHBondContact O-N 3.17Å; M268-A271 PolarHBondContact O-N 3.25Å; A271-L274 PolarHBondContact O-N 3.42Å; A271-A275 WeakPolarHBondContact O-CB 3.26Å; A271-A275 PolarHBondContact O-N 3.12Å; A271-L341 HydrophobicContact CB-CB 4.27Å; A271-L341 HydrophobicContact CB-CD2 4.01Å
272R95.1Very high91.9Very high56 Ų5635.4 Ų35.421%0.21118%0.175CC..Hα-helixtrans-60.3-47.9174.7-177.2-177.158.275.9-2.3112M268 T269 I270 L274 A275 E276 V374 V375 L378M268-R272 PolarHBondContact O-N 3.11Å; M268-R272 VanDerWaalsContact O-N 3.15Å; T269-R272 PolarHBondContact O-N 3.45Å; I270-R272 VanDerWaalsContact C-N 3.35Å; I270-R272 PolarHBondContact O-N 3.19Å; R272-L274 VanDerWaalsContact C-N 3.33Å; R272-L274 PolarHBondContact O-N 3.4Å; R272-A275 WeakPolarHBondContact O-CB 3.35Å; R272-A275 PolarHBondContact O-N 3.21Å; R272-E276 IonicContact CZ-OE1 2.67Å; R272-E276 IonicContact NH1-OE1 3.79Å; R272-E276 PolarHBondContact NH1-OE1 3.03Å; R272-E276 WeakPolarHBondContact O-CG 3.38Å; R272-E276 PolarHBondContact O-N 2.88Å; R272-V374 HydrophobicContact CG-CG1 4.46Å; R272-V375 HydrophobicContact CG-CG2 4.38Å; R272-L378 HydrophobicContact CG-CD1 4.02Å
273Q94.7Very high91.9Very high73 Ų7336.9 Ų36.934%0.34119%0.186SC..Hα-helixtrans-62.8-39.1179.7-74.5177.2-13.700112.5F251 T269 I270 E276 I277F251-Q273 HydrophobicContact CE2-CB 3.83Å; F251-Q273 HydrophobicContact CZ-CB 3.92Å; T269-Q273 WeakPolarHBondContact O-CG 3.29Å; T269-Q273 PolarHBondContact O-N 3.43Å; I270-Q273 PolarHBondContact O-N 3.33Å; Q273-E276 WeakPolarHBondContact O-CB 3.41Å; Q273-E276 PolarHBondContact O-N 2.89Å; Q273-I277 WeakPolarHBondContact O-CG1 3.47Å; Q273-I277 PolarHBondContact O-N 3.28Å; Q273-I277 VanDerWaalsContact O-N 3.08Å
274L95.9Very high91.6Very high0 Ų042.4 Ų42.40%021%0.211CC..Hα-helixtrans-66.5-43.1175178.657.7000111.1V248 F251 R252 L255 I270 A271 R272 E276 I277 L278 L341V248-L274 HydrophobicContact CB-CD1 4.37Å; V248-L274 HydrophobicContact CG1-CD1 3.85Å; V248-L274 HydrophobicContact CG2-CD1 4.1Å; F251-L274 HydrophobicContact CB-CB 4.32Å; F251-L274 HydrophobicContact CB-CD1 4.33Å; F251-L274 HydrophobicContact CB-CD2 4.12Å; F251-L274 HydrophobicContact CB-CG 4.49Å; F251-L274 HydrophobicContact CD2-CB 3.78Å; F251-L274 HydrophobicContact CD2-CD1 4.13Å; F251-L274 HydrophobicContact CD2-CG 4.46Å; F251-L274 HydrophobicContact CE2-CB 4.48Å; F251-L274 HydrophobicContact CG-CB 4.45Å; R252-L274 HydrophobicContact CG-CD2 3.99Å; L255-L274 HydrophobicContact CD1-CD2 3.74Å; I270-L274 WeakPolarHBondContact O-CB 3.37Å; I270-L274 PolarHBondContact O-N 2.93Å; A271-L274 PolarHBondContact O-N 3.42Å; R272-L274 VanDerWaalsContact C-N 3.33Å; R272-L274 PolarHBondContact O-N 3.4Å; L274-E276 VanDerWaalsContact C-N 3.29Å; L274-E276 PolarHBondContact O-N 2.97Å; L274-I277 PolarHBondContact O-N 2.75Å; L274-I277 VanDerWaalsContact O-N 3.12Å; L274-L278 HydrophobicContact CD1-CD1 4.22Å; L274-L278 HydrophobicContact CD1-CG 4.21Å; L274-L278 HydrophobicContact CG-CD1 3.94Å; L274-L278 HydrophobicContact CG-CG 4.43Å; L274-L278 VanDerWaalsContact O-CG 3.32Å; L274-L278 WeakPolarHBondContact O-CG 3.36Å; L274-L278 PolarHBondContact O-N 3.48Å; L274-L341 HydrophobicContact CB-CD1 3.88Å; L274-L341 HydrophobicContact CD2-CD1 3.57Å; L274-L341 HydrophobicContact CD2-CD2 4.36Å; L274-L341 HydrophobicContact CG-CD1 3.52Å
275A96.5Very high91.4Very high0 Ų048.3 Ų48.30%024%0.239CC..Hα-helixtrans-58.8-40.2174.400000112.2A271 R272 L278 L279 A338 L341 L342A271-A275 WeakPolarHBondContact O-CB 3.26Å; A271-A275 PolarHBondContact O-N 3.12Å; R272-A275 WeakPolarHBondContact O-CB 3.35Å; R272-A275 PolarHBondContact O-N 3.21Å; A275-L278 PolarHBondContact O-N 2.95Å; A275-L279 WeakPolarHBondContact O-CB 3.35Å; A275-L279 VanDerWaalsContact O-CG 3.28Å; A275-L279 WeakPolarHBondContact O-CG 3.14Å; A275-L279 PolarHBondContact O-N 3.47Å; A275-A338 HydrophobicContact CB-CB 4.36Å; A275-L341 HydrophobicContact CB-CB 4.06Å; A275-L341 HydrophobicContact CB-CD1 4.41Å; A275-L342 HydrophobicContact CB-CD1 4.34Å; A275-L342 HydrophobicContact CB-CD2 3.79Å; A275-L342 HydrophobicContact CB-CG 3.71Å
276E94.5Very high91.3Very high29 Ų2943.4 Ų43.414%0.13621%0.213CC..Hα-helixtrans-58.3-51172-71.9176.2-158.500111.4R272 Q273 L274 L278 L279 R280 L378R272-E276 IonicContact CZ-OE1 2.67Å; R272-E276 IonicContact NH1-OE1 3.79Å; R272-E276 PolarHBondContact NH1-OE1 3.03Å; R272-E276 WeakPolarHBondContact O-CG 3.38Å; R272-E276 PolarHBondContact O-N 2.88Å; Q273-E276 WeakPolarHBondContact O-CB 3.41Å; Q273-E276 PolarHBondContact O-N 2.89Å; L274-E276 VanDerWaalsContact C-N 3.29Å; L274-E276 PolarHBondContact O-N 2.97Å; E276-L278 VanDerWaalsContact C-N 3.28Å; E276-L278 PolarHBondContact O-N 2.82Å; E276-L279 PolarHBondContact O-N 2.93Å; E276-L279 VanDerWaalsContact O-N 3.17Å; E276-R280 WeakPolarHBondContact O-CG 3.25Å; E276-R280 PolarHBondContact O-N 3.29Å; E276-R280 IonicContact OE2-CZ 3.68Å; E276-R280 IonicContact OE2-NH2 2.86Å; E276-R280 PolarHBondContact OE2-NH2 3.38Å; E276-L378 HydrophobicContact CG-CD1 3.39Å; E276-L378 HydrophobicContact CG-CD2 3.78Å; E276-L378 HydrophobicContact CG-CG 4.21Å
277I93.3Very high91.2Very high24 Ų2444.3 Ų44.312%0.12322%0.215CC..Iπ-helixtrans-59.5-41.8180-65.5165.7000110.7F239 L244 V248 F251 Q273 L274 L279 G281 M282F239-I277 HydrophobicContact CD1-CD1 4.38Å; F239-I277 HydrophobicContact CE1-CD1 3.51Å; F239-I277 HydrophobicContact CE2-CD1 4.2Å; F239-I277 HydrophobicContact CZ-CD1 3.39Å; L244-I277 HydrophobicContact CD2-CG2 4.22Å; V248-I277 HydrophobicContact CG2-CG2 3.85Å; F251-I277 HydrophobicContact CD2-CD1 4.13Å; F251-I277 HydrophobicContact CE2-CD1 3.69Å; Q273-I277 WeakPolarHBondContact O-CG1 3.47Å; Q273-I277 PolarHBondContact O-N 3.28Å; Q273-I277 VanDerWaalsContact O-N 3.08Å; L274-I277 PolarHBondContact O-N 2.75Å; L274-I277 VanDerWaalsContact O-N 3.12Å; I277-L279 VanDerWaalsContact C-N 3.31Å; I277-L279 PolarHBondContact O-N 3.19Å; I277-G281 CarbonylContact O-C 3.39Å; I277-G281 WeakPolarHBondContact O-CA 3.44Å; I277-G281 PolarHBondContact O-N 3.26Å; I277-M282 HydrophobicContact CG2-CG 4.39Å; I277-M282 HydrophobicContact CG2-SD 4.41Å; I277-M282 PolarHBondContact O-N 3.04Å; I277-M282 VanDerWaalsContact O-N 3.17Å
278L94Very high91.1Very high1 Ų144.2 Ų44.21%0.00522%0.215CC..Iπ-helixtrans-64-34.6178.7-70.7163.4000112.9L274 A275 E276 M282 Y287 E337 A338 L341L274-L278 HydrophobicContact CD1-CD1 4.22Å; L274-L278 HydrophobicContact CD1-CG 4.21Å; L274-L278 HydrophobicContact CG-CD1 3.94Å; L274-L278 HydrophobicContact CG-CG 4.43Å; L274-L278 VanDerWaalsContact O-CG 3.32Å; L274-L278 WeakPolarHBondContact O-CG 3.36Å; L274-L278 PolarHBondContact O-N 3.48Å; A275-L278 PolarHBondContact O-N 2.95Å; E276-L278 VanDerWaalsContact C-N 3.28Å; E276-L278 PolarHBondContact O-N 2.82Å; L278-M282 HydrophobicContact CD2-CE 4.23Å; L278-M282 HydrophobicContact CD2-SD 3.82Å; L278-Y287 HydrophobicContact CD2-CD2 4.25Å; L278-Y287 HydrophobicContact CD2-CE2 4.24Å; L278-E337 HydrophobicContact CD1-CB 3.82Å; L278-E337 HydrophobicContact CD1-CG 3.59Å; L278-E337 WeakPolarHBondContact CD2-OE2 3.32Å; L278-A338 HydrophobicContact CB-CB 4.23Å; L278-L341 HydrophobicContact CD1-CD1 3.67Å
279L93.7Very high91.1Very high10 Ų1043.3 Ų43.35%0.05221%0.211CC..Iπ-helixtrans-85.2-31.6-176-71173.5000114.8A275 E276 I277 A338 L342 L378 A382 R385A275-L279 WeakPolarHBondContact O-CB 3.35Å; A275-L279 VanDerWaalsContact O-CG 3.28Å; A275-L279 WeakPolarHBondContact O-CG 3.14Å; A275-L279 PolarHBondContact O-N 3.47Å; E276-L279 PolarHBondContact O-N 2.93Å; E276-L279 VanDerWaalsContact O-N 3.17Å; I277-L279 VanDerWaalsContact C-N 3.31Å; I277-L279 PolarHBondContact O-N 3.19Å; L279-A338 HydrophobicContact CD1-CB 4.26Å; L279-A338 HydrophobicContact CD2-CB 3.85Å; L279-A338 HydrophobicContact CG-CB 3.8Å; L279-L342 HydrophobicContact CD1-CD1 4.27Å; L279-L378 HydrophobicContact CD1-CB 4.14Å; L279-L378 HydrophobicContact CD1-CD2 4.06Å; L279-A382 HydrophobicContact CD1-CB 4.13Å; L279-A382 HydrophobicContact CD2-CB 3.82Å; L279-R385 PolarHBondContact O-NH1 2.99Å; L279-R385 PolarHBondContact O-NH2 2.99Å
280R90.6Very high91.2Very high191 Ų19142.2 Ų42.272%0.72121%0.205SC*.Iπ-helixtrans-118.5-21.2-177.351.9155.6175.5159.2-4.5115.1E276E276-R280 WeakPolarHBondContact O-CG 3.25Å; E276-R280 PolarHBondContact O-N 3.29Å; E276-R280 IonicContact OE2-CZ 3.68Å; E276-R280 IonicContact OE2-NH2 2.86Å; E276-R280 PolarHBondContact OE2-NH2 3.38Å
281G85.6Confident90.8Very high35 Ų3547.5 Ų47.536%0.36123%0.232SC..Iπ-helixtrans-104.6-11.5-175.500000114.5I277 L300I277-G281 CarbonylContact O-C 3.39Å; I277-G281 WeakPolarHBondContact O-CA 3.44Å; I277-G281 PolarHBondContact O-N 3.26Å; G281-L300 VanDerWaalsContact O-CD2 3.31Å; G281-L300 WeakPolarHBondContact O-CD2 3.34Å
282M86.4Confident90.3Very high18 Ų1853 Ų539%0.08926%0.258CS..  trans-133.3153.8-178.1-62.6-178.954.600111.5V248 I277 L278 Y287 W288 L300 N334V248-M282 HydrophobicContact CG2-SD 4.32Å; I277-M282 HydrophobicContact CG2-CG 4.39Å; I277-M282 HydrophobicContact CG2-SD 4.41Å; I277-M282 PolarHBondContact O-N 3.04Å; I277-M282 VanDerWaalsContact O-N 3.17Å; L278-M282 HydrophobicContact CD2-CE 4.23Å; L278-M282 HydrophobicContact CD2-SD 3.82Å; M282-Y287 HydrophobicContact CE-CD2 4.43Å; M282-W288 HydrophobicContact CE-CE3 3.92Å; M282-W288 HydrophobicContact CE-CH2 4.34Å; M282-W288 HydrophobicContact CE-CZ3 3.5Å; M282-W288 VanDerWaalsContact CE-CZ3 3.5Å; M282-W288 HydrophobicContact SD-CZ3 4.33Å; M282-L300 HydrophobicContact CB-CD2 4.33Å; M282-L300 HydrophobicContact CE-CD1 3.87Å; M282-L300 HydrophobicContact CG-CD1 3.65Å; M282-L300 HydrophobicContact CG-CD2 3.87Å; M282-L300 HydrophobicContact CG-CG 4.42Å; M282-L300 HydrophobicContact SD-CD1 3.9Å; M282-N334 VanDerWaalsContact CB-ND2 3.34Å; M282-N334 WeakPolarHBondContact CB-ND2 3.38Å
283C86.8Confident89.6Confident69 Ų6957.1 Ų57.147%0.46629%0.285SS..  trans-119.2171.5170.168.60000111.1Q285 S286 Y287 N334C283-Q285 VanDerWaalsContact C-N 3.26Å; C283-Q285 PolarHBondContact O-N 3.45Å; C283-S286 PolarHBondContact N-OG 3.3Å; C283-S286 PolarHBondContact O-N 3.09Å; C283-S286 PolarHBondContact O-OG 2.84Å; C283-Y287 PolarHBondContact O-N 3.08Å; C283-N334 PolarHBondContact O-ND2 3.47Å; C283-N334 PolarHBondContact O-OD1 3.07Å
284E85.5Confident88.8Confident120 Ų12054.2 Ų54.256%0.56127%0.272SS*.G310 helixtrans-57.3-36.4-177.7-68.2169.4-169.600112.9S286 Y287 N334 R386E284-S286 VanDerWaalsContact C-N 3.29Å; E284-S286 PolarHBondContact O-N 2.83Å; E284-Y287 PolarHBondContact O-N 2.95Å; E284-N334 VanDerWaalsContact CA-OD1 3.29Å; E284-N334 WeakPolarHBondContact CA-OD1 3.46Å; E284-N334 PolarHBondContact N-OD1 3.48Å; E284-R386 IonicContact OE1-CZ 2.59Å; E284-R386 VanDerWaalsContact OE1-CZ 3.32Å; E284-R386 IonicContact OE1-NH1 2.68Å; E284-R386 PolarHBondContact OE1-NH1 3.12Å; E284-R386 IonicContact OE1-NH2 3.93Å; E284-R386 PolarHBondContact OE1-NH2 3.18Å
285Q84.3Confident87.7Confident185 Ų18556.7 Ų56.786%0.86429%0.288SS*.G310 helixtrans-72.5-22.2178.7-63.2179.3-0.600113.8C283C283-Q285 VanDerWaalsContact C-N 3.26Å; C283-Q285 PolarHBondContact O-N 3.45Å
286S85.3Confident86.2Confident2 Ų261.3 Ų61.31%0.01432%0.316CS..G310 helixtrans-96-4.4-178.865.90000113.3C283 E284C283-S286 PolarHBondContact N-OG 3.3Å; C283-S286 PolarHBondContact O-N 3.09Å; C283-S286 PolarHBondContact O-OG 2.84Å; E284-S286 VanDerWaalsContact C-N 3.29Å; E284-S286 PolarHBondContact O-N 2.83Å
287Y89.4Confident84.6Confident33 Ų3364.8 Ų64.813%0.12934%0.339CS..  trans-76.9145.4-177.1-177.8-93.2000111.7L278 M282 C283 E284 P331 Q332 E333 N334 E337L278-Y287 HydrophobicContact CD2-CD2 4.25Å; L278-Y287 HydrophobicContact CD2-CE2 4.24Å; M282-Y287 HydrophobicContact CE-CD2 4.43Å; C283-Y287 PolarHBondContact O-N 3.08Å; E284-Y287 PolarHBondContact O-N 2.95Å; Y287-P331 WeakPolarHBondContact OH-CB 3.41Å; Y287-P331 PolarHBondContact OH-O 3.28Å; Y287-Q332 WeakPolarHBondContact CD1-O 3.41Å; Y287-Q332 WeakPolarHBondContact CE1-O 3.37Å; Y287-E333 VanDerWaalsContact CE2-C 3.49Å; Y287-N334 VanDerWaalsContact CB-OD1 3.27Å; Y287-N334 WeakPolarHBondContact CB-OD1 3.39Å; Y287-N334 HydrophobicContact CD2-CB 4.26Å; Y287-E337 HydrophobicContact CE2-CB 4.22Å; Y287-E337 VanDerWaalsContact CE2-OE2 3.24Å; Y287-E337 WeakPolarHBondContact CE2-OE2 3.26Å
288W90.6Very high83.2Confident13 Ų1364 Ų645%0.04934%0.336CS..  trans-137.6146.8167.871.1103000108.9T245 V248 R252 M282 P294 L300T245-W288 HydrophobicContact CG2-CH2 4.28Å; T245-W288 HydrophobicContact CG2-CZ3 4.47Å; V248-W288 HydrophobicContact CB-CH2 3.9Å; V248-W288 HydrophobicContact CB-CZ2 4.17Å; V248-W288 HydrophobicContact CG1-CH2 3.65Å; V248-W288 HydrophobicContact CG1-CZ2 3.7Å; R252-W288 VanDerWaalsContact CZ-O 3.24Å; R252-W288 PolarHBondContact NH1-O 3.17Å; R252-W288 PolarHBondContact NH2-O 2.83Å; M282-W288 HydrophobicContact CE-CE3 3.92Å; M282-W288 HydrophobicContact CE-CH2 4.34Å; M282-W288 HydrophobicContact CE-CZ3 3.5Å; M282-W288 VanDerWaalsContact CE-CZ3 3.5Å; M282-W288 HydrophobicContact SD-CZ3 4.33Å; W288-P294 HydrophobicContact CD2-CB 4.03Å; W288-P294 HydrophobicContact CG-CB 4.22Å; W288-P294 HydrophobicContact CZ2-CB 4.1Å; W288-L300 HydrophobicContact CZ3-CD1 3.96Å
289S90.8Very high81.5Confident6 Ų668.4 Ų68.44%0.04237%0.365CS..  trans-63.1147-179174.50000111.6L291 E292 C330S289-L291 PolarHBondContact O-N 3.34Å; S289-L291 PolarHBondContact OG-N 2.79Å; S289-E292 WeakPolarHBondContact CB-OE2 3.15Å; S289-E292 PolarHBondContact N-OE2 2.96Å; S289-E292 VanDerWaalsContact N-OE2 3.16Å; S289-E292 PolarHBondContact O-N 2.95Å; S289-C330 PolarHBondContact OG-SG 3.44Å
290P91.3Very high79.9Confident20 Ų2069.8 Ų69.813%0.1337%0.372CS..THydrogen-bonded Turntrans-60-14.8175.2-2534.5000115.5R256R256-P290 PolarHBondContact NH1-O 2.9Å
291L88Confident78.5Confident112 Ų11261.9 Ų61.959%0.58634%0.344SS*.THydrogen-bonded Turntrans-100.2-11.7176-61.4-176.8000113.4R256 S289 C330R256-L291 VanDerWaalsContact CZ-CD2 3.44Å; R256-L291 VanDerWaalsContact NH2-CD2 3.31Å; S289-L291 PolarHBondContact O-N 3.34Å; S289-L291 PolarHBondContact OG-N 2.79Å; L291-C330 HydrophobicContact CD1-CB 4.16Å
292E84.9Confident77Confident117 Ų11764.4 Ų64.455%0.54735%0.349SS..SBendtrans-90.4153.7178.3-72.9172.2166.200111.3S289S289-E292 WeakPolarHBondContact CB-OE2 3.15Å; S289-E292 PolarHBondContact N-OE2 2.96Å; S289-E292 VanDerWaalsContact N-OE2 3.16Å; S289-E292 PolarHBondContact O-N 2.95Å
293D78.9Confident75.1Confident142 Ų14269.1 Ų69.176%0.75938%0.381SS*.PPolyproline II helixtrans-68.3137.1168.3-70.1-38.8000109.2
294P78.7Confident73.3Confident12 Ų1271.8 Ų71.88%0.07840%0.396CS..PPolyproline II helixtrans-66.3156.8177.928.7-34.4000111.1W288 Y310W288-P294 HydrophobicContact CD2-CB 4.03Å; W288-P294 HydrophobicContact CG-CB 4.22Å; W288-P294 HydrophobicContact CZ2-CB 4.1Å; P294-Y310 HydrophobicContact CB-CG 4.5Å; P294-Y310 HydrophobicContact CG-CD1 3.24Å; P294-Y310 HydrophobicContact CG-CD2 3.74Å; P294-Y310 HydrophobicContact CG-CE1 3.9Å; P294-Y310 HydrophobicContact CG-CE2 4.36Å; P294-Y310 HydrophobicContact CG-CG 3.13Å
295P72.4Confident71.6Confident51 Ų5170 Ų7033%0.33139%0.387SS..PPolyproline II helixtrans-59.9144.6-177.424.5-34.4000112.1V297P295-V297 PolarHBondContact O-N 2.94Å
296T64.4Low69.4Low97 Ų9769.6 Ų69.660%0.59539%0.385SS*.SBendtrans-65.3-27.9179.852.80000113.2T309T296-T309 HydrophobicContact CG2-CG2 3.96Å
297V62.8Low67.4Low102 Ų10271.9 Ų71.962%0.61841%0.409SS*.SBendtrans-130.1106168.3-178.80000106.3P295P295-V297 PolarHBondContact O-N 2.94Å
298S62.5Low65.4Low7 Ų777.6 Ų77.65%0.04944%0.437CS..  trans-82.7133.5178.6-179.20000110.7T245 L300 D301T245-S298 WeakPolarHBondContact CG2-OG 3.32Å; S298-L300 PolarHBondContact O-N 3.4Å; S298-L300 VanDerWaalsContact O-N 3.13Å; S298-L300 WeakPolarHBondContact OG-CB 3.16Å; S298-L300 PolarHBondContact OG-N 2.82Å; S298-D301 PolarHBondContact O-N 2.85Å; S298-D301 VanDerWaalsContact O-N 3.13Å; S298-D301 VanDerWaalsContact O-O 3.09Å
299P59.1Low63.5Low95 Ų9581.4 Ų81.462%0.61746%0.462SS*.THydrogen-bonded Turntrans-61.7-15.8170.8-16.828.6000113.4
300L60.3Low61.8Low39 Ų3984.2 Ų84.220%0.20447%0.472CS..THydrogen-bonded Turntrans-82.5-20.1179.5-55.4170.5000112.6L244 G281 M282 W288 S298L244-L300 HydrophobicContact CB-CB 4.34Å; G281-L300 VanDerWaalsContact O-CD2 3.31Å; G281-L300 WeakPolarHBondContact O-CD2 3.34Å; M282-L300 HydrophobicContact CB-CD2 4.33Å; M282-L300 HydrophobicContact CE-CD1 3.87Å; M282-L300 HydrophobicContact CG-CD1 3.65Å; M282-L300 HydrophobicContact CG-CD2 3.87Å; M282-L300 HydrophobicContact CG-CG 4.42Å; M282-L300 HydrophobicContact SD-CD1 3.9Å; W288-L300 HydrophobicContact CZ3-CD1 3.96Å; S298-L300 PolarHBondContact O-N 3.4Å; S298-L300 VanDerWaalsContact O-N 3.13Å; S298-L300 WeakPolarHBondContact OG-CB 3.16Å; S298-L300 PolarHBondContact OG-N 2.82Å
301D61Low60.3Low24 Ų2492.9 Ų92.913%0.12850%0.502CS..SBendtrans-103.6141.5178.6-59.8-38.1000108.4L244 T245 S298L244-D301 PolarHBondContact N-OD1 2.71Å; T245-D301 WeakPolarHBondContact CB-OD2 3.49Å; T245-D301 WeakPolarHBondContact CG2-OD2 3.3Å; T245-D301 PolarHBondContact OG1-OD2 2.72Å; S298-D301 PolarHBondContact O-N 2.85Å; S298-D301 VanDerWaalsContact O-N 3.13Å; S298-D301 VanDerWaalsContact O-O 3.09Å
302N52.6Low59.3Low88 Ų8891.5 Ų91.547%0.47149%0.491SS..  trans-58138-175.7-96.8-47.8000111.9T304 Q305N302-T304 PolarHBondContact O-N 3.05Å; N302-Q305 PolarHBondContact O-N 3.25Å
303P47.9Very low58.7Low117 Ų11790.9 Ų90.976%0.7649%0.491SS*.THydrogen-bonded Turntrans-63.5-10.3-17818.6-27.1000114.8
304T47.4Very low59Low126 Ų12685 Ų8577%0.77346%0.459SS*.THydrogen-bonded Turntrans-81.9-12.5173.552.30000113.6N302 Q306N302-T304 PolarHBondContact O-N 3.05Å; T304-Q306 PolarHBondContact O-N 3Å
305Q50.4Low59.3Low81 Ų8190.7 Ų90.738%0.37949%0.494SS..SBendtrans-81.192.1169.5-65.9-172.410.700108.5N302 G307N302-Q305 PolarHBondContact O-N 3.25Å; Q305-G307 PolarHBondContact O-N 3.44Å; Q305-G307 VanDerWaalsContact O-N 3.15Å
306Q39Very low59.9Low177 Ų17789.7 Ų89.783%0.82749%0.485SS*.  trans-54.3119.9174.3-81.8179.5-19.300110.9T304 H308T304-Q306 PolarHBondContact O-N 3Å; Q306-H308 PolarHBondContact O-N 3.5Å
307G43.1Very low60.9Low51 Ų5191.8 Ų91.853%0.52649%0.493SS..  trans9.885.9160.900000117.2Q305Q305-G307 PolarHBondContact O-N 3.44Å; Q305-G307 VanDerWaalsContact O-N 3.15Å
308H47.2Very low62.1Low153 Ų15390 Ų9071%0.70848%0.475SS*.  trans-103.9103.8154-71.2-48.9000107.6Q306 Y310Q306-H308 PolarHBondContact O-N 3.5Å; H308-Y310 PolarHBondContact O-N 3.27Å
309T49.7Very low63.3Low92 Ų9293.9 Ų93.956%0.56450%0.5SS*.  trans-45.7125.8165.922.30000108.8T296 R311T296-T309 HydrophobicContact CG2-CG2 3.96Å; T309-R311 VanDerWaalsContact C-N 3.28Å; T309-R311 PolarHBondContact O-N 2.85Å
310Y55.6Low64.9Low66 Ų6690.3 Ų90.326%0.25948%0.477SS..  trans-61.198.5167.5178-93.9000107.5R246 E253 P294 H308R246-Y310 HydrophobicContact CG-CD2 4.19Å; R246-Y310 HydrophobicContact CG-CE2 4.46Å; E253-Y310 PolarHBondContact OE1-OH 2.8Å; P294-Y310 HydrophobicContact CB-CG 4.5Å; P294-Y310 HydrophobicContact CG-CD1 3.24Å; P294-Y310 HydrophobicContact CG-CD2 3.74Å; P294-Y310 HydrophobicContact CG-CE1 3.9Å; P294-Y310 HydrophobicContact CG-CE2 4.36Å; P294-Y310 HydrophobicContact CG-CG 3.13Å; H308-Y310 PolarHBondContact O-N 3.27Å
311R60.3Low66.5Low202 Ų20294.4 Ų94.476%0.76249%0.489SS*.  trans-134.6123.9171.8-161.1171.8-173.21742.4105.7T309 N313T309-R311 VanDerWaalsContact C-N 3.28Å; T309-R311 PolarHBondContact O-N 2.85Å; R311-N313 PolarHBondContact O-N 3.33Å; R311-N313 PolarHBondContact O-OD1 3.21Å
312K67.4Low68.1Low83 Ų8395.7 Ų95.736%0.36150%0.498SS..  trans-53.2127.6170.2-78.7-164.7173.5-167.60107.9D190 E253 Y314D190-K312 IonicContact OD2-NZ 3.67Å; D190-K312 PolarHBondContact OD2-NZ 3.4Å; E253-K312 VanDerWaalsContact CD-NZ 3.3Å; E253-K312 WeakPolarHBondContact OE1-CE 3.3Å; E253-K312 IonicContact OE1-NZ 3.07Å; E253-K312 PolarHBondContact OE1-NZ 3.06Å; E253-K312 WeakPolarHBondContact OE2-CE 3.18Å; E253-K312 IonicContact OE2-NZ 3.53Å; E253-K312 PolarHBondContact OE2-NZ 2.89Å; K312-Y314 PolarHBondContact O-N 2.83Å; K312-Y314 VanDerWaalsContact O-N 3.16Å
313N72.9Confident70.1Confident103 Ų10396.2 Ų96.255%0.55149%0.494SS*.SBendtrans-74.20.1-179.6-67.8-20.6000112.5Q179 R311Q179-N313 PolarHBondContact NE2-ND2 2.6Å; R311-N313 PolarHBondContact O-N 3.33Å; R311-N313 PolarHBondContact O-OD1 3.21Å
314Y83.8Confident72.1Confident20 Ų2095.8 Ų95.88%0.07849%0.494CS..  trans-146.6164-179.169.1-84.6000111.2T183 E186 K187 D190 K312 L316T183-Y314 HydrophobicContact CG2-CD1 3.91Å; T183-Y314 HydrophobicContact CG2-CE1 4.41Å; E186-Y314 VanDerWaalsContact C-OH 3.25Å; E186-Y314 HydrophobicContact CB-CE1 3.83Å; E186-Y314 WeakPolarHBondContact CB-OH 3.38Å; E186-Y314 PolarHBondContact O-OH 3.06Å; K187-Y314 HydrophobicContact CD-CD2 4.41Å; K187-Y314 HydrophobicContact CD-CG 4.45Å; K187-Y314 HydrophobicContact CG-CD1 4.17Å; K187-Y314 HydrophobicContact CG-CD2 3.74Å; K187-Y314 HydrophobicContact CG-CE1 4.11Å; K187-Y314 HydrophobicContact CG-CE2 3.68Å; K187-Y314 HydrophobicContact CG-CG 4Å; D190-Y314 PolarHBondContact OD2-OH 3.01Å; K312-Y314 PolarHBondContact O-N 2.83Å; K312-Y314 VanDerWaalsContact O-N 3.16Å; Y314-L316 HydrophobicContact CD2-CD2 3.92Å; Y314-L316 HydrophobicContact CD2-CG 4.02Å; Y314-L316 HydrophobicContact CE2-CD1 4.25Å; Y314-L316 HydrophobicContact CE2-CD2 3.96Å; Y314-L316 HydrophobicContact CE2-CG 3.79Å
315T84.4Confident74Confident131 Ų13192.1 Ų92.180%0.80448%0.481SS*.  trans-134.7130.4169.8-57.60000108
316L86Confident75.7Confident29 Ų2997.9 Ų97.915%0.15251%0.508CS..  trans-86.7139.7176-60.9178.6000109.8L130 K187 D190 I191 Y314 R318L130-L316 HydrophobicContact CD1-CB 4.26Å; L130-L316 HydrophobicContact CD1-CD2 4.24Å; K187-L316 HydrophobicContact CG-CD2 4.45Å; D190-L316 HydrophobicContact CB-CD1 3.54Å; I191-L316 HydrophobicContact CD1-CD2 4.4Å; I191-L316 HydrophobicContact CG1-CD1 3.97Å; I191-L316 HydrophobicContact CG1-CD2 4.47Å; Y314-L316 HydrophobicContact CD2-CD2 3.92Å; Y314-L316 HydrophobicContact CD2-CG 4.02Å; Y314-L316 HydrophobicContact CE2-CD1 4.25Å; Y314-L316 HydrophobicContact CE2-CD2 3.96Å; Y314-L316 HydrophobicContact CE2-CG 3.79Å; L316-R318 PolarHBondContact O-N 3.18Å; L316-R318 VanDerWaalsContact O-N 3.16Å
317N84.8Confident78.2Confident141 Ų14197.3 Ų97.375%0.75451%0.511SS*.SBendtrans-63.1-20.5175.6-67.1-18.2000112.9
318R87.6Confident80.5Confident65 Ų6599.5 Ų99.525%0.24551%0.51CS..SBendtrans-144.9104.8175.3-174.6177.4177.5-1680.6109.9L130 L194 E198 L316L130-R318 HydrophobicContact CB-CB 4.09Å; L194-R318 HydrophobicContact CD1-CG 4.23Å; L194-R318 HydrophobicContact CD2-CB 4.28Å; L194-R318 HydrophobicContact CD2-CG 3.92Å; L194-R318 WeakPolarHBondContact CD2-O 3.43Å; E198-R318 IonicContact OE1-NH2 2.78Å; E198-R318 PolarHBondContact OE1-NH2 3.15Å; E198-R318 IonicContact OE2-NH2 2.87Å; E198-R318 PolarHBondContact OE2-NH2 3.15Å; L316-R318 PolarHBondContact O-N 3.18Å; L316-R318 VanDerWaalsContact O-N 3.16Å
319P88.8Confident82.7Confident88 Ų8898.6 Ų98.657%0.57150%0.504SS*.PPolyproline II helixtrans-82.5162.7175.232.3-34.1000112.3
320P93.1Very high84.8Confident21 Ų2195.4 Ų95.414%0.13649%0.486CS..PPolyproline II helixtrans-63.4156.1169.427.9-34.8000111.5L193 L194L193-P320 HydrophobicContact CB-CB 3.9Å; L193-P320 HydrophobicContact CB-CG 4.17Å; L194-P320 HydrophobicContact CB-CB 4.34Å
321R94.2Very high86.6Confident124 Ų12492.7 Ų92.747%0.46848%0.476SS..PPolyproline II helixtrans-71.5138.2174.3-60.1-178-167.1166.29.6109.7Q197 E198 K201 A257 V258Q197-R321 PolarHBondContact NE2-O 3.23Å; E198-R321 IonicContact OE1-CZ 2.72Å; E198-R321 IonicContact OE1-NE 2.69Å; E198-R321 IonicContact OE1-NH2 3.31Å; E198-R321 PolarHBondContact OE1-NH2 2.74Å; K201-R321 VanDerWaalsContact NZ-NH2 3.19Å; A257-R321 WeakPolarHBondContact CA-O 3.48Å; V258-R321 HydrophobicContact CB-CB 4.49Å; V258-R321 HydrophobicContact CG2-CB 4.04Å; V258-R321 PolarHBondContact N-O 3.37Å
322V94.5Very high88.2Confident51 Ų5188.7 Ų88.731%0.30947%0.466SS..BIsolated β-bridgetrans-119.3149.6-179.1165.90000109.1R256 S324R256-V322 HydrophobicContact CB-CG1 3.92Å; R256-V322 CarbonylContact O-C 3.26Å; R256-V322 VanDerWaalsContact O-CA 3.29Å; R256-V322 WeakPolarHBondContact O-CA 3.39Å; R256-V322 WeakPolarHBondContact O-CG1 3.09Å; V322-S324 PolarHBondContact O-N 2.95Å
323Y93.3Very high89.3Confident100 Ų10087.5 Ų87.539%0.39246%0.462SS..  trans-58.8117.7170.4-66.1-72.4000110.2R256 A257 V258 E259R256-Y323 VanDerWaalsContact O-CD2 3.24Å; R256-Y323 WeakPolarHBondContact O-CD2 3.44Å; R256-Y323 PolarHBondContact O-N 2.88Å; A257-Y323 WeakPolarHBondContact O-CE2 3.41Å; V258-Y323 HydrophobicContact CG1-CE1 4.43Å; V258-Y323 HydrophobicContact CG2-CD1 4.31Å; V258-Y323 HydrophobicContact CG2-CE1 4.36Å; E259-Y323 WeakPolarHBondContact CB-OH 3.45Å; E259-Y323 PolarHBondContact N-OH 3.29Å
324S90Very high90.2Very high108 Ų10883 Ų8376%0.75544%0.437SS*.  trans-138.2135.5-176.861.50000111V322 L328V322-S324 PolarHBondContact O-N 2.95Å; S324-L328 VanDerWaalsContact C-CD1 3.48Å
325G88.4Confident90.7Very high49 Ų4982.3 Ų82.351%0.50544%0.435SS..  trans168.6143.8176.400000110.7N327 L328G325-N327 PolarHBondContact O-N 2.9Å; G325-L328 PolarHBondContact O-N 3.02Å
326E85.1Confident91.2Very high201 Ų20179.4 Ų79.494%0.93941%0.413SS*.THydrogen-bonded Turntrans-65.6-25.4-175-64179.8173.900113.2
327N91.6Very high91.7Very high166 Ų16678.4 Ų78.489%0.88841%0.407SS*.THydrogen-bonded Turntrans-98.69.5-178.7-62.8-34.4000113.6G325G325-N327 PolarHBondContact O-N 2.9Å
328L90.9Very high92.2Very high97 Ų9771.7 Ų71.751%0.50837%0.371SS..SBendtrans-75.6135.2176.8-68.1178.3000110.1S324 G325 C330S324-L328 VanDerWaalsContact C-CD1 3.48Å; G325-L328 PolarHBondContact O-N 3.02Å; L328-C330 PolarHBondContact O-N 3.09Å
329F94.1Very high92.7Very high133 Ų13370.2 Ų70.258%0.58337%0.368SS*.  trans-63.4132.1173.7176.2-105.6000110.6P331 E336 L340F329-P331 HydrophobicContact CD1-CG 4.44Å; F329-P331 HydrophobicContact CE1-CB 4.37Å; F329-P331 HydrophobicContact CE1-CG 3.85Å; F329-E336 HydrophobicContact CZ-CB 4.42Å; F329-L340 HydrophobicContact CD1-CD2 4.07Å; F329-L340 HydrophobicContact CE1-CD2 4.21Å
330C93.3Very high93.1Very high26 Ų2669 Ų6918%0.17636%0.357CS..  trans-125.8118.6175-173.80000108.8S289 L291 L328 Q332S289-C330 PolarHBondContact OG-SG 3.44Å; L291-C330 HydrophobicContact CD1-CB 4.16Å; L328-C330 PolarHBondContact O-N 3.09Å; C330-Q332 PolarHBondContact O-NE2 2.93Å
331P95.1Very high93.2Very high8 Ų868.5 Ų68.55%0.05235%0.353CS..  trans-60.9136-180-23.633.2000113.1Y287 F329 E336 E337 L340Y287-P331 WeakPolarHBondContact OH-CB 3.41Å; Y287-P331 PolarHBondContact OH-O 3.28Å; F329-P331 HydrophobicContact CD1-CG 4.44Å; F329-P331 HydrophobicContact CE1-CB 4.37Å; F329-P331 HydrophobicContact CE1-CG 3.85Å; P331-E336 HydrophobicContact CB-CB 4.05Å; P331-E337 HydrophobicContact CB-CB 3.59Å; P331-E337 HydrophobicContact CB-CG 4.25Å; P331-E337 HydrophobicContact CG-CB 3.91Å; P331-E337 HydrophobicContact CG-CG 4.11Å; P331-L340 HydrophobicContact CG-CD2 3.78Å
332Q92.3Very high93.3Very high119 Ų11962.6 Ų62.656%0.55633%0.33SS*.  trans-104.2-14.3-178.7-57.4-56.6-50.400113.3Y287 C330 E336Y287-Q332 WeakPolarHBondContact CD1-O 3.41Å; Y287-Q332 WeakPolarHBondContact CE1-O 3.37Å; C330-Q332 PolarHBondContact O-NE2 2.93Å; Q332-E336 PolarHBondContact N-OE2 3.39Å
333E91.6Very high93.4Very high58 Ų5863.1 Ų63.127%0.27133%0.331SS..SBendtrans-141.5167.5176.660151.4-150.600113.3Y287 T335 E336 E337 R386Y287-E333 VanDerWaalsContact CE2-C 3.49Å; E333-T335 VanDerWaalsContact C-N 3.3Å; E333-T335 PolarHBondContact O-N 3.16Å; E333-T335 WeakPolarHBondContact OE1-CB 3.37Å; E333-E336 HydrophobicContact CG-CB 3.99Å; E333-E336 HydrophobicContact CG-CG 3.6Å; E333-E336 PolarHBondContact O-N 2.93Å; E333-E337 PolarHBondContact O-N 2.94Å; E333-E337 VanDerWaalsContact O-N 3.11Å; E333-R386 IonicContact OE1-NH2 3.43Å; E333-R386 IonicContact OE2-NH2 2.68Å; E333-R386 PolarHBondContact OE2-NH2 3.08Å
334N91.8Very high93.4Very high7 Ų760.7 Ų60.74%0.03732%0.324CS..Hα-helixtrans-55-43.6-178.5-5468.8000112.6M282 C283 E284 Y287 A338M282-N334 VanDerWaalsContact CB-ND2 3.34Å; M282-N334 WeakPolarHBondContact CB-ND2 3.38Å; C283-N334 PolarHBondContact O-ND2 3.47Å; C283-N334 PolarHBondContact O-OD1 3.07Å; E284-N334 VanDerWaalsContact CA-OD1 3.29Å; E284-N334 WeakPolarHBondContact CA-OD1 3.46Å; E284-N334 PolarHBondContact N-OD1 3.48Å; Y287-N334 VanDerWaalsContact CB-OD1 3.27Å; Y287-N334 WeakPolarHBondContact CB-OD1 3.39Å; Y287-N334 HydrophobicContact CD2-CB 4.26Å; N334-A338 VanDerWaalsContact O-CB 3.23Å; N334-A338 WeakPolarHBondContact O-CB 3.47Å; N334-A338 PolarHBondContact O-N 3.43Å
335T92.9Very high93.5Very high7 Ų755.7 Ų55.74%0.04329%0.289CS..Hα-helixtrans-72.7-39.9-174.2-49.90000110.7E333 A338 L339 A382 R386E333-T335 VanDerWaalsContact C-N 3.3Å; E333-T335 PolarHBondContact O-N 3.16Å; E333-T335 WeakPolarHBondContact OE1-CB 3.37Å; T335-A338 PolarHBondContact O-N 3.35Å; T335-L339 HydrophobicContact CG2-CD1 4.06Å; T335-L339 HydrophobicContact CG2-CG 4.25Å; T335-L339 WeakPolarHBondContact O-CB 3.27Å; T335-L339 WeakPolarHBondContact O-CG 3.34Å; T335-L339 PolarHBondContact O-N 3.02Å; T335-A382 HydrophobicContact CG2-CB 4.46Å; T335-R386 HydrophobicContact CG2-CG 4.03Å; T335-R386 PolarHBondContact OG1-NE 2.98Å; T335-R386 PolarHBondContact OG1-NH2 3.44Å
336E95Very high93.6Very high70 Ų7053.6 Ų53.633%0.32727%0.266SS..Hα-helixtrans-58.8-47.8173.2-73.5-180177.900112.2F329 P331 Q332 E333 L339 L340F329-E336 HydrophobicContact CZ-CB 4.42Å; P331-E336 HydrophobicContact CB-CB 4.05Å; Q332-E336 PolarHBondContact N-OE2 3.39Å; E333-E336 HydrophobicContact CG-CB 3.99Å; E333-E336 HydrophobicContact CG-CG 3.6Å; E333-E336 PolarHBondContact O-N 2.93Å; E336-L339 PolarHBondContact O-N 3.4Å; E336-L340 WeakPolarHBondContact O-CB 3.46Å; E336-L340 PolarHBondContact O-N 3.05Å
337E97Very high93.9Very high8 Ų846.6 Ų46.64%0.03724%0.239CC..Hα-helixtrans-66-44.9179.5-169.9-180-17200110.4R252 L278 Y287 P331 E333 L339 L340 L341R252-E337 IonicContact CZ-OE1 3.84Å; R252-E337 IonicContact CZ-OE2 3.89Å; R252-E337 IonicContact NE-OE1 2.88Å; R252-E337 PolarHBondContact NE-OE1 3.48Å; R252-E337 IonicContact NE-OE2 2.87Å; R252-E337 IonicContact NH2-OE1 2.76Å; R252-E337 IonicContact NH2-OE2 3.28Å; R252-E337 PolarHBondContact NH2-OE2 3.01Å; L278-E337 HydrophobicContact CD1-CB 3.82Å; L278-E337 HydrophobicContact CD1-CG 3.59Å; L278-E337 WeakPolarHBondContact CD2-OE2 3.32Å; Y287-E337 HydrophobicContact CE2-CB 4.22Å; Y287-E337 VanDerWaalsContact CE2-OE2 3.24Å; Y287-E337 WeakPolarHBondContact CE2-OE2 3.26Å; P331-E337 HydrophobicContact CB-CB 3.59Å; P331-E337 HydrophobicContact CB-CG 4.25Å; P331-E337 HydrophobicContact CG-CB 3.91Å; P331-E337 HydrophobicContact CG-CG 4.11Å; E333-E337 PolarHBondContact O-N 2.94Å; E333-E337 VanDerWaalsContact O-N 3.11Å; E337-L339 PolarHBondContact O-N 2.95Å; E337-L340 PolarHBondContact O-N 3.35Å; E337-L341 HydrophobicContact CG-CD1 3.88Å; E337-L341 HydrophobicContact CG-CG 4.32Å; E337-L341 WeakPolarHBondContact O-CB 3.21Å; E337-L341 WeakPolarHBondContact O-CD1 3.15Å; E337-L341 WeakPolarHBondContact O-CG 3.38Å; E337-L341 PolarHBondContact O-N 3.32Å
338A96.6Very high93.7Very high0 Ų039.2 Ų39.20%020%0.2CC..Hα-helixtrans-59.2-44.7176.700000111.9A275 L278 L279 N334 T335 L341 L342A275-A338 HydrophobicContact CB-CB 4.36Å; L278-A338 HydrophobicContact CB-CB 4.23Å; L279-A338 HydrophobicContact CD1-CB 4.26Å; L279-A338 HydrophobicContact CD2-CB 3.85Å; L279-A338 HydrophobicContact CG-CB 3.8Å; N334-A338 VanDerWaalsContact O-CB 3.23Å; N334-A338 WeakPolarHBondContact O-CB 3.47Å; N334-A338 PolarHBondContact O-N 3.43Å; T335-A338 PolarHBondContact O-N 3.35Å; A338-L341 PolarHBondContact O-N 3.46Å; A338-L342 WeakPolarHBondContact O-CB 2.8Å; A338-L342 WeakPolarHBondContact O-CD1 3.1Å; A338-L342 WeakPolarHBondContact O-CG 3.29Å; A338-L342 PolarHBondContact O-N 3Å
339L96.4Very high93.3Very high34 Ų3435.1 Ų35.118%0.17818%0.18CC..Hα-helixtrans-63.4-45.7177.5-73.8174.5000111.7T335 E336 E337 L341 L342 L343 L379 A382 L383T335-L339 HydrophobicContact CG2-CD1 4.06Å; T335-L339 HydrophobicContact CG2-CG 4.25Å; T335-L339 WeakPolarHBondContact O-CB 3.27Å; T335-L339 WeakPolarHBondContact O-CG 3.34Å; T335-L339 PolarHBondContact O-N 3.02Å; E336-L339 PolarHBondContact O-N 3.4Å; E337-L339 PolarHBondContact O-N 2.95Å; L339-L341 VanDerWaalsContact C-N 3.32Å; L339-L341 PolarHBondContact O-N 3.49Å; L339-L342 PolarHBondContact O-N 3.07Å; L339-L343 WeakPolarHBondContact O-CB 3.33Å; L339-L343 VanDerWaalsContact O-CG 3.24Å; L339-L343 WeakPolarHBondContact O-CG 3.5Å; L339-L343 PolarHBondContact O-N 3.21Å; L339-L379 HydrophobicContact CD2-CD2 3.89Å; L339-A382 HydrophobicContact CD2-CB 3.89Å; L339-A382 HydrophobicContact CG-CB 4.43Å; L339-L383 HydrophobicContact CD1-CD2 4.1Å; L339-L383 HydrophobicContact CD2-CD2 3.74Å; L339-L383 HydrophobicContact CD2-CG 3.92Å
340L96.9Very high92.8Very high63 Ų6330.8 Ų30.833%0.3316%0.163SC..Hα-helixtrans-56.8-48.2176.5176.663000111.1F329 P331 E336 E337 L343 I344F329-L340 HydrophobicContact CD1-CD2 4.07Å; F329-L340 HydrophobicContact CE1-CD2 4.21Å; P331-L340 HydrophobicContact CG-CD2 3.78Å; E336-L340 WeakPolarHBondContact O-CB 3.46Å; E336-L340 PolarHBondContact O-N 3.05Å; E337-L340 PolarHBondContact O-N 3.35Å; L340-L343 PolarHBondContact O-N 3.3Å; L340-I344 HydrophobicContact CD1-CD1 4.09Å; L340-I344 HydrophobicContact CD1-CG1 4.49Å; L340-I344 HydrophobicContact CG-CD1 4.01Å; L340-I344 VanDerWaalsContact O-CG1 3.26Å; L340-I344 WeakPolarHBondContact O-CG1 3.49Å; L340-I344 PolarHBondContact O-N 2.96Å
341L97.3Very high92.3Very high10 Ų1037.5 Ų37.55%0.05218%0.184CC..Hα-helixtrans-65-41.3-179.6-67.8170.5000112.6L255 A271 L274 A275 L278 E337 A338 L339 I344 S345L255-L341 HydrophobicContact CD1-CD2 3.6Å; A271-L341 HydrophobicContact CB-CB 4.27Å; A271-L341 HydrophobicContact CB-CD2 4.01Å; L274-L341 HydrophobicContact CB-CD1 3.88Å; L274-L341 HydrophobicContact CD2-CD1 3.57Å; L274-L341 HydrophobicContact CD2-CD2 4.36Å; L274-L341 HydrophobicContact CG-CD1 3.52Å; A275-L341 HydrophobicContact CB-CB 4.06Å; A275-L341 HydrophobicContact CB-CD1 4.41Å; L278-L341 HydrophobicContact CD1-CD1 3.67Å; E337-L341 HydrophobicContact CG-CD1 3.88Å; E337-L341 HydrophobicContact CG-CG 4.32Å; E337-L341 WeakPolarHBondContact O-CB 3.21Å; E337-L341 WeakPolarHBondContact O-CD1 3.15Å; E337-L341 WeakPolarHBondContact O-CG 3.38Å; E337-L341 PolarHBondContact O-N 3.32Å; A338-L341 PolarHBondContact O-N 3.46Å; L339-L341 VanDerWaalsContact C-N 3.32Å; L339-L341 PolarHBondContact O-N 3.49Å; L341-I344 PolarHBondContact O-N 3.31Å; L341-S345 WeakPolarHBondContact O-CB 3.4Å; L341-S345 PolarHBondContact O-N 3.47Å
342L96.1Very high91.1Very high0 Ų042.7 Ų42.70%021%0.212CC..Hα-helixtrans-67.2-39.1177.2-69.9168.8000111.6A275 L279 A338 L339 S345 E346 V375 L378 L379A275-L342 HydrophobicContact CB-CD1 4.34Å; A275-L342 HydrophobicContact CB-CD2 3.79Å; A275-L342 HydrophobicContact CB-CG 3.71Å; L279-L342 HydrophobicContact CD1-CD1 4.27Å; A338-L342 WeakPolarHBondContact O-CB 2.8Å; A338-L342 WeakPolarHBondContact O-CD1 3.1Å; A338-L342 WeakPolarHBondContact O-CG 3.29Å; A338-L342 PolarHBondContact O-N 3Å; L339-L342 PolarHBondContact O-N 3.07Å; L342-S345 PolarHBondContact O-N 2.86Å; L342-E346 WeakPolarHBondContact O-CB 3.36Å; L342-E346 PolarHBondContact O-N 3.28Å; L342-V375 HydrophobicContact CB-CG1 4.28Å; L342-V375 HydrophobicContact CD2-CG1 4.01Å; L342-V375 WeakPolarHBondContact O-CG1 3.32Å; L342-L378 HydrophobicContact CD1-CB 3.75Å; L342-L378 HydrophobicContact CD2-CB 3.59Å; L342-L378 HydrophobicContact CD2-CD1 3.82Å; L342-L378 HydrophobicContact CD2-CG 4.38Å; L342-L378 HydrophobicContact CG-CB 4.34Å; L342-L379 HydrophobicContact CB-CD2 3.63Å; L342-L379 HydrophobicContact CB-CG 3.94Å; L342-L379 HydrophobicContact CD1-CD2 3.88Å; L342-L379 HydrophobicContact CD1-CG 4.06Å; L342-L379 HydrophobicContact CG-CD2 4.4Å
343L94.7Very high90.3Very high61 Ų6138 Ų3832%0.31919%0.193SC..Hα-helixtrans-66.6-38.7174.9-69.9173.3000111.9L339 L340 E346 S347L339-L343 WeakPolarHBondContact O-CB 3.33Å; L339-L343 VanDerWaalsContact O-CG 3.24Å; L339-L343 WeakPolarHBondContact O-CG 3.5Å; L339-L343 PolarHBondContact O-N 3.21Å; L340-L343 PolarHBondContact O-N 3.3Å; L343-E346 PolarHBondContact O-N 3.07Å; L343-S347 WeakPolarHBondContact O-CB 3.45Å; L343-S347 PolarHBondContact O-N 3.49Å; L343-S347 PolarHBondContact O-OG 3.12Å
344I93.7Very high89.6Confident50 Ų5037.4 Ų37.426%0.25619%0.194SC..Hα-helixtrans-61.2-51.6172.1-69.4165.8000109.5L340 L341 E346 S347 M348L340-I344 HydrophobicContact CD1-CD1 4.09Å; L340-I344 HydrophobicContact CD1-CG1 4.49Å; L340-I344 HydrophobicContact CG-CD1 4.01Å; L340-I344 VanDerWaalsContact O-CG1 3.26Å; L340-I344 WeakPolarHBondContact O-CG1 3.49Å; L340-I344 PolarHBondContact O-N 2.96Å; L341-I344 PolarHBondContact O-N 3.31Å; I344-E346 VanDerWaalsContact C-N 3.33Å; I344-E346 PolarHBondContact O-N 3.36Å; I344-S347 PolarHBondContact O-N 2.96Å; I344-S347 PolarHBondContact O-OG 2.92Å; I344-M348 HydrophobicContact CG2-CE 3.72Å; I344-M348 HydrophobicContact CG2-SD 3.98Å; I344-M348 WeakPolarHBondContact O-CG 3.36Å; I344-M348 PolarHBondContact O-N 2.94Å
345S92.9Very high88.9Confident2 Ų241.7 Ų41.71%0.01422%0.216CC..Hα-helixtrans-61-39.9179.2-171.80000112.3M268 L341 L342 M348 A349M268-S345 PolarHBondContact O-OG 3.02Å; L341-S345 WeakPolarHBondContact O-CB 3.4Å; L341-S345 PolarHBondContact O-N 3.47Å; L342-S345 PolarHBondContact O-N 2.86Å; S345-M348 PolarHBondContact O-N 3.21Å; S345-A349 WeakPolarHBondContact O-CB 3.44Å; S345-A349 PolarHBondContact O-N 2.86Å
346E91.3Very high88.1Confident5 Ų543.3 Ų43.32%0.02323%0.228CC..Hα-helixtrans-61.7-48.3175.5-172.2-158.6-17900110.3L342 L343 I344 M348 A349 N350 V375 Y376 R398L342-E346 WeakPolarHBondContact O-CB 3.36Å; L342-E346 PolarHBondContact O-N 3.28Å; L343-E346 PolarHBondContact O-N 3.07Å; I344-E346 VanDerWaalsContact C-N 3.33Å; I344-E346 PolarHBondContact O-N 3.36Å; E346-M348 VanDerWaalsContact C-N 3.27Å; E346-M348 PolarHBondContact O-N 3.35Å; E346-A349 PolarHBondContact O-N 3.47Å; E346-N350 WeakPolarHBondContact O-CB 3.44Å; E346-N350 PolarHBondContact O-N 2.6Å; E346-N350 PolarHBondContact O-ND2 3.02Å; E346-N350 VanDerWaalsContact O-ND2 3.1Å; E346-V375 HydrophobicContact CB-CG1 4.04Å; E346-Y376 HydrophobicContact CG-CE1 4.12Å; E346-Y376 WeakPolarHBondContact CG-OH 3.23Å; E346-Y376 WeakPolarHBondContact OE1-CE1 3.47Å; E346-Y376 PolarHBondContact OE1-OH 2.84Å; E346-R398 IonicContact OE1-CZ 2.85Å; E346-R398 IonicContact OE1-NE 2.82Å; E346-R398 IonicContact OE1-NH1 3.94Å; E346-R398 PolarHBondContact OE1-NH1 3.49Å; E346-R398 IonicContact OE1-NH2 3.37Å; E346-R398 PolarHBondContact OE1-NH2 2.86Å; E346-R398 IonicContact OE2-CZ 3.03Å; E346-R398 IonicContact OE2-NH1 3.45Å; E346-R398 PolarHBondContact OE2-NH1 3.43Å; E346-R398 IonicContact OE2-NH2 3.12Å; E346-R398 PolarHBondContact OE2-NH2 2.91Å; E346-R398 VanDerWaalsContact OE2-NH2 3.12Å
347S90.1Very high87.2Confident54 Ų5449.5 Ų49.538%0.37825%0.248SC..Hα-helixtrans-62.9-34.6-17978.20000112.6L343 I344L343-S347 WeakPolarHBondContact O-CB 3.45Å; L343-S347 PolarHBondContact O-N 3.49Å; L343-S347 PolarHBondContact O-OG 3.12Å; I344-S347 PolarHBondContact O-N 2.96Å; I344-S347 PolarHBondContact O-OG 2.92Å
348M87.3Confident86.4Confident12 Ų1253.2 Ų53.26%0.05927%0.267CS..Hα-helixtrans-73.8-48.6176.5-70176.3174.500111.1M268 I344 S345 E346 N350 R351M268-M348 HydrophobicContact CB-CB 4.07Å; M268-M348 HydrophobicContact CB-SD 3.85Å; M268-M348 HydrophobicContact CG-CB 3.96Å; M268-M348 HydrophobicContact SD-CB 3.95Å; I344-M348 HydrophobicContact CG2-CE 3.72Å; I344-M348 HydrophobicContact CG2-SD 3.98Å; I344-M348 WeakPolarHBondContact O-CG 3.36Å; I344-M348 PolarHBondContact O-N 2.94Å; S345-M348 PolarHBondContact O-N 3.21Å; E346-M348 VanDerWaalsContact C-N 3.27Å; E346-M348 PolarHBondContact O-N 3.35Å; M348-N350 PolarHBondContact O-N 3.06Å; M348-R351 WeakPolarHBondContact O-CB 3.41Å; M348-R351 PolarHBondContact O-N 3.26Å
349A83.7Confident85.5Confident10 Ų1058.5 Ų58.58%0.08330%0.302CS..Hα-helixtrans-58.6-32.2177.600000112.4M268 S345 E346 R351 A353M268-A349 HydrophobicContact SD-CB 3.98Å; S345-A349 WeakPolarHBondContact O-CB 3.44Å; S345-A349 PolarHBondContact O-N 2.86Å; E346-A349 PolarHBondContact O-N 3.47Å; A349-R351 VanDerWaalsContact C-N 3.31Å; A349-R351 PolarHBondContact O-N 3.11Å; A349-A353 PolarHBondContact O-N 2.91Å
350N83.2Confident84.8Confident42 Ų4264.9 Ų64.923%0.22533%0.33CS..THydrogen-bonded Turntrans-67.9-23.4176.7-74.3-30.9000114.7E346 M348 K401 F402E346-N350 WeakPolarHBondContact O-CB 3.44Å; E346-N350 PolarHBondContact O-N 2.6Å; E346-N350 PolarHBondContact O-ND2 3.02Å; E346-N350 VanDerWaalsContact O-ND2 3.1Å; M348-N350 PolarHBondContact O-N 3.06Å; N350-K401 PolarHBondContact ND2-NZ 3.4Å; N350-K401 WeakPolarHBondContact OD1-CE 3.15Å; N350-K401 PolarHBondContact OD1-NZ 3.4Å; N350-F402 VanDerWaalsContact OD1-CE2 3.26Å; N350-F402 WeakPolarHBondContact OD1-CE2 3.25Å; N350-F402 WeakPolarHBondContact OD1-CZ 3.35Å
351R81.6Confident84Confident167 Ų16765 Ų6563%0.6333%0.33SS*.THydrogen-bonded Turntrans-77.5-38.2-179.1-69.4176.1-177.6177.82.1112M348 A349M348-R351 WeakPolarHBondContact O-CB 3.41Å; M348-R351 PolarHBondContact O-N 3.26Å; A349-R351 VanDerWaalsContact C-N 3.31Å; A349-R351 PolarHBondContact O-N 3.11Å
352D71Confident83.1Confident117 Ų11767.8 Ų67.863%0.62634%0.344SS*.SBendtrans-95.76.5-175.9-59.7-29.5000112.7V354D352-V354 PolarHBondContact O-N 3.37Å
353A76.2Confident82.4Confident20 Ų2073.3 Ų73.317%0.16537%0.374CS..  trans-68.2119.7-17700000112.8A349 L355 F402A349-A353 PolarHBondContact O-N 2.91Å; A353-L355 HydrophobicContact CB-CD2 4.28Å; A353-L355 HydrophobicContact CB-CG 4.45Å; A353-L355 PolarHBondContact O-N 3.24Å; A353-F402 HydrophobicContact CB-CD1 4.44Å; A353-F402 HydrophobicContact CB-CE1 3.45Å; A353-F402 VanDerWaalsContact CB-CE1 3.45Å; A353-F402 HydrophobicContact CB-CZ 4.08Å
354V75.7Confident81.7Confident47 Ų4773.6 Ų73.629%0.28538%0.376SS..  trans-82.3105.6170.5-178.20000109.5D352 H361 D364 R365 S368D352-V354 PolarHBondContact O-N 3.37Å; V354-H361 HydrophobicContact CG1-CB 3.92Å; V354-D364 HydrophobicContact CB-CB 3.98Å; V354-D364 HydrophobicContact CG1-CB 4.1Å; V354-D364 HydrophobicContact CG2-CB 3.89Å; V354-R365 WeakPolarHBondContact O-CG 3.44Å; V354-S368 PolarHBondContact N-OG 3.28Å
355L76.8Confident81Confident96 Ų9673.7 Ų73.750%0.50337%0.373SS..  trans-97.4-3.6-178.9-58.7178.3000113.9A353 R357 K401 F402A353-L355 HydrophobicContact CB-CD2 4.28Å; A353-L355 HydrophobicContact CB-CG 4.45Å; A353-L355 PolarHBondContact O-N 3.24Å; L355-R357 PolarHBondContact O-N 3.08Å; L355-K401 HydrophobicContact CD2-CG 4.42Å; L355-F402 HydrophobicContact CD2-CD1 4.25Å; L355-F402 HydrophobicContact CD2-CE1 4.43Å
356S77Confident80.5Confident42 Ų4277.7 Ų77.729%0.29439%0.393SS..  trans-62.6133.9-177.9-176.80000111.2I358 R365S356-I358 VanDerWaalsContact C-N 3.31Å; S356-I358 WeakPolarHBondContact OG-CD1 3.45Å; S356-I358 WeakPolarHBondContact OG-CG1 3.45Å; S356-R365 WeakPolarHBondContact O-CD 3.48Å
357R76.2Confident79.9Confident200 Ų20082.6 Ų82.676%0.75542%0.418SS*.  trans-89.75.2-179.2-63.1-175.3-177.3-178.9-0.4113.9L355L355-R357 PolarHBondContact O-N 3.08Å
358I80.7Confident79.5Confident85 Ų8580.7 Ų80.744%0.43641%0.405SS..SBendtrans-67.3136.9-179.6-57.7169.7000109S356 E360 H361S356-I358 VanDerWaalsContact C-N 3.31Å; S356-I358 WeakPolarHBondContact OG-CD1 3.45Å; S356-I358 WeakPolarHBondContact OG-CG1 3.45Å; I358-E360 HydrophobicContact CG2-CB 4.19Å; I358-E360 HydrophobicContact CG2-CG 4.28Å; I358-E360 PolarHBondContact O-N 3.28Å; I358-E360 VanDerWaalsContact O-N 3.1Å; I358-H361 PolarHBondContact O-N 3.28Å; I358-H361 VanDerWaalsContact O-N 3.11Å
359P76.8Confident79.2Confident112 Ų11282.2 Ų82.273%0.72741%0.413SS*.G310 helixtrans-54.7-30.1-178.1-28.335.5000114.8H361 N362P359-H361 VanDerWaalsContact C-N 3.27Å; P359-H361 PolarHBondContact O-N 2.94Å; P359-N362 WeakPolarHBondContact O-CB 3.47Å; P359-N362 PolarHBondContact O-N 3.47Å
360E81Confident79.2Confident167 Ų16788.1 Ų88.178%0.7844%0.439SS*.G310 helixtrans-63.3-29.6-179.6-64.7170.7-173.500113.1I358I358-E360 HydrophobicContact CG2-CB 4.19Å; I358-E360 HydrophobicContact CG2-CG 4.28Å; I358-E360 PolarHBondContact O-N 3.28Å; I358-E360 VanDerWaalsContact O-N 3.1Å
361H80.8Confident78.8Confident67 Ų6788.3 Ų88.331%0.3144%0.444SS..G310 helixtrans-9414.7179.7-68.8-59.7000113.6V354 I358 P359 N363 D364 R365V354-H361 HydrophobicContact CG1-CB 3.92Å; I358-H361 PolarHBondContact O-N 3.28Å; I358-H361 VanDerWaalsContact O-N 3.11Å; P359-H361 VanDerWaalsContact C-N 3.27Å; P359-H361 PolarHBondContact O-N 2.94Å; H361-N363 VanDerWaalsContact C-N 3.3Å; H361-N363 PolarHBondContact O-N 3.46Å; H361-D364 IonicContact CG-OD2 3.84Å; H361-D364 IonicContact ND1-OD2 2.65Å; H361-D364 PolarHBondContact ND1-OD2 3.33Å; H361-D364 PolarHBondContact O-N 2.86Å; H361-R365 WeakPolarHBondContact O-CG 3.5Å; H361-R365 PolarHBondContact O-N 2.95Å
362N78.6Confident78.9Confident68 Ų6880.5 Ų80.536%0.36442%0.415SS..Hα-helixtrans-59.8-40.9-175.9-169.936.8000112.5P359 R365 I366P359-N362 WeakPolarHBondContact O-CB 3.47Å; P359-N362 PolarHBondContact O-N 3.47Å; N362-R365 PolarHBondContact O-N 3.48Å; N362-R365 PolarHBondContact OD1-NH2 2.83Å; N362-I366 WeakPolarHBondContact O-CG1 3.42Å; N362-I366 PolarHBondContact O-N 3.05Å; N362-I366 VanDerWaalsContact O-N 3.14Å
363N81.9Confident79.6Confident115 Ų11576.4 Ų76.462%0.61540%0.396SS*.Hα-helixtrans-66.7-41.7178.5-68.9-20.3000112H361 R365 I366 I367H361-N363 VanDerWaalsContact C-N 3.3Å; H361-N363 PolarHBondContact O-N 3.46Å; N363-R365 VanDerWaalsContact C-N 3.28Å; N363-R365 PolarHBondContact O-N 3.41Å; N363-I366 PolarHBondContact O-N 3.43Å; N363-I366 VanDerWaalsContact O-N 3.15Å; N363-I367 WeakPolarHBondContact O-CG1 3.35Å; N363-I367 PolarHBondContact O-N 3.05Å; N363-I367 VanDerWaalsContact O-N 3.09Å
364D78.9Confident80.3Confident68 Ų6877.7 Ų77.736%0.36440%0.401SS..Hα-helixtrans-64.1-35.9179.3-55.2-31.7000111.6V354 H361 I367 S368V354-D364 HydrophobicContact CB-CB 3.98Å; V354-D364 HydrophobicContact CG1-CB 4.1Å; V354-D364 HydrophobicContact CG2-CB 3.89Å; H361-D364 IonicContact CG-OD2 3.84Å; H361-D364 IonicContact ND1-OD2 2.65Å; H361-D364 PolarHBondContact ND1-OD2 3.33Å; H361-D364 PolarHBondContact O-N 2.86Å; D364-I367 PolarHBondContact O-N 2.62Å; D364-S368 WeakPolarHBondContact O-CB 3.42Å; D364-S368 PolarHBondContact O-N 3.22Å; D364-S368 PolarHBondContact O-OG 2.93Å
365R80.5Confident81.1Confident51 Ų5175.5 Ų75.519%0.19239%0.388CS..Hα-helixtrans-65.9-41.3173.2-69.1175.2-16.8-178.81.5112.3V354 S356 H361 N362 N363 I367 S368 L369V354-R365 WeakPolarHBondContact O-CG 3.44Å; S356-R365 WeakPolarHBondContact O-CD 3.48Å; H361-R365 WeakPolarHBondContact O-CG 3.5Å; H361-R365 PolarHBondContact O-N 2.95Å; N362-R365 PolarHBondContact O-N 3.48Å; N362-R365 PolarHBondContact OD1-NH2 2.83Å; N363-R365 VanDerWaalsContact C-N 3.28Å; N363-R365 PolarHBondContact O-N 3.41Å; R365-I367 VanDerWaalsContact C-N 3.3Å; R365-I367 PolarHBondContact O-N 3.11Å; R365-S368 PolarHBondContact O-N 3.32Å; R365-L369 VanDerWaalsContact O-CB 3.23Å; R365-L369 WeakPolarHBondContact O-CB 3.44Å; R365-L369 PolarHBondContact O-N 3.07Å
366I80.5Confident81.9Confident87 Ų8771.1 Ų71.145%0.44637%0.365SS..Hα-helixtrans-62.4-41.9178.2-68.7165.2000109.9N362 N363 L369 Q370N362-I366 WeakPolarHBondContact O-CG1 3.42Å; N362-I366 PolarHBondContact O-N 3.05Å; N362-I366 VanDerWaalsContact O-N 3.14Å; N363-I366 PolarHBondContact O-N 3.43Å; N363-I366 VanDerWaalsContact O-N 3.15Å; I366-L369 PolarHBondContact O-N 2.88Å; I366-Q370 WeakPolarHBondContact O-CB 3.14Å; I366-Q370 PolarHBondContact O-N 3.22Å
367I80.6Confident82.7Confident107 Ų10771.6 Ų71.655%0.54936%0.364SS..Hα-helixtrans-66.6-44176.7-63165.5000110.9N363 D364 R365 L369 Q370 S371N363-I367 WeakPolarHBondContact O-CG1 3.35Å; N363-I367 PolarHBondContact O-N 3.05Å; N363-I367 VanDerWaalsContact O-N 3.09Å; D364-I367 PolarHBondContact O-N 2.62Å; R365-I367 VanDerWaalsContact C-N 3.3Å; R365-I367 PolarHBondContact O-N 3.11Å; I367-L369 VanDerWaalsContact C-N 3.3Å; I367-L369 PolarHBondContact O-N 3.45Å; I367-Q370 PolarHBondContact O-N 3.23Å; I367-S371 WeakPolarHBondContact O-CB 3.43Å; I367-S371 PolarHBondContact O-N 2.99Å; I367-S371 PolarHBondContact O-OG 3.4Å
368S80.3Confident83.7Confident14 Ų1462.9 Ų62.910%0.09833%0.332CS..Hα-helixtrans-60.9-39.9175.6-59.20000111.6V354 D364 R365 S371 A372V354-S368 PolarHBondContact N-OG 3.28Å; D364-S368 WeakPolarHBondContact O-CB 3.42Å; D364-S368 PolarHBondContact O-N 3.22Å; D364-S368 PolarHBondContact O-OG 2.93Å; R365-S368 PolarHBondContact O-N 3.32Å; S368-S371 PolarHBondContact O-OG 2.88Å; S368-A372 WeakPolarHBondContact O-CB 3.47Å; S368-A372 PolarHBondContact O-N 3.49Å; S368-A372 VanDerWaalsContact O-N 3.14Å
369L81.8Confident84.4Confident45 Ų4558.9 Ų58.924%0.23631%0.312CS..Hα-helixtrans-68-47.4177.117765.3000111.4R365 I366 I367 S371 A372 S373 F402 E406R365-L369 VanDerWaalsContact O-CB 3.23Å; R365-L369 WeakPolarHBondContact O-CB 3.44Å; R365-L369 PolarHBondContact O-N 3.07Å; I366-L369 PolarHBondContact O-N 2.88Å; I367-L369 VanDerWaalsContact C-N 3.3Å; I367-L369 PolarHBondContact O-N 3.45Å; L369-S371 VanDerWaalsContact C-N 3.3Å; L369-S371 PolarHBondContact O-N 2.93Å; L369-A372 PolarHBondContact O-N 3.28Å; L369-S373 WeakPolarHBondContact O-CB 3.5Å; L369-S373 PolarHBondContact O-N 3.5Å; L369-S373 PolarHBondContact O-OG 3.42Å; L369-F402 HydrophobicContact CD1-CB 4.09Å; L369-E406 HydrophobicContact CD2-CG 3.99Å
370Q82.6Confident85.3Confident133 Ų13354.7 Ų54.762%0.62128%0.284SS*.Hα-helixtrans-64.4-35.9-178.5-172.2179.29.900112.3I366 I367 S373I366-Q370 WeakPolarHBondContact O-CB 3.14Å; I366-Q370 PolarHBondContact O-N 3.22Å; I367-Q370 PolarHBondContact O-N 3.23Å; Q370-S373 PolarHBondContact O-OG 2.97Å
371S75.4Confident86Confident47 Ų4750.5 Ų50.533%0.32927%0.267SS..Hα-helixtrans-70.6-38.3176.253.10000112.3I367 S368 L369I367-S371 WeakPolarHBondContact O-CB 3.43Å; I367-S371 PolarHBondContact O-N 2.99Å; I367-S371 PolarHBondContact O-OG 3.4Å; S368-S371 PolarHBondContact O-OG 2.88Å; L369-S371 VanDerWaalsContact C-N 3.3Å; L369-S371 PolarHBondContact O-N 2.93Å
372A83Confident86.7Confident3 Ų347.3 Ų47.33%0.02525%0.252CS..Hα-helixtrans-78.5-37.2177.900000113.5S368 L369 V374 V375 Y376 F402S368-A372 WeakPolarHBondContact O-CB 3.47Å; S368-A372 PolarHBondContact O-N 3.49Å; S368-A372 VanDerWaalsContact O-N 3.14Å; L369-A372 PolarHBondContact O-N 3.28Å; A372-V374 VanDerWaalsContact C-N 3.35Å; A372-V374 PolarHBondContact O-N 3.25Å; A372-V375 WeakPolarHBondContact O-CB 3.46Å; A372-V375 PolarHBondContact O-N 3.04Å; A372-Y376 HydrophobicContact CB-CD2 4.35Å; A372-Y376 HydrophobicContact CB-CE2 4.21Å; A372-Y376 WeakPolarHBondContact O-CD2 3.42Å; A372-Y376 PolarHBondContact O-N 3.04Å; A372-Y376 VanDerWaalsContact O-N 3.08Å; A372-F402 HydrophobicContact CB-CD1 4.48Å; A372-F402 HydrophobicContact CB-CD2 4.15Å; A372-F402 HydrophobicContact CB-CE1 4.31Å; A372-F402 HydrophobicContact CB-CE2 4.02Å; A372-F402 HydrophobicContact CB-CG 4.38Å; A372-F402 HydrophobicContact CB-CZ 4.09Å
373S87.2Confident87.4Confident31 Ų3144.3 Ų44.322%0.21724%0.236CC..Hα-helixtrans-61-43.3-17368.20000111.7L369 Q370 V375 Y376 D377L369-S373 WeakPolarHBondContact O-CB 3.5Å; L369-S373 PolarHBondContact O-N 3.5Å; L369-S373 PolarHBondContact O-OG 3.42Å; Q370-S373 PolarHBondContact O-OG 2.97Å; S373-V375 VanDerWaalsContact C-N 3.26Å; S373-V375 PolarHBondContact O-N 3.45Å; S373-Y376 PolarHBondContact O-N 3.43Å; S373-Y376 VanDerWaalsContact O-N 3.14Å; S373-D377 VanDerWaalsContact O-CG 3.28Å; S373-D377 PolarHBondContact O-N 3.23Å
374V89.8Confident87.9Confident46 Ų4639.8 Ų39.828%0.27922%0.216SC..Hα-helixtrans-61.1-37.6177.2-178.70000111.2R272 A372 D377 L378R272-V374 HydrophobicContact CG-CG1 4.46Å; A372-V374 VanDerWaalsContact C-N 3.35Å; A372-V374 PolarHBondContact O-N 3.25Å; V374-D377 PolarHBondContact O-N 2.85Å; V374-L378 HydrophobicContact CG1-CD1 4Å; V374-L378 WeakPolarHBondContact O-CB 3.36Å; V374-L378 WeakPolarHBondContact O-CD1 3.39Å; V374-L378 WeakPolarHBondContact O-CG 3.37Å; V374-L378 PolarHBondContact O-N 3.12Å
375V92.8Very high88.4Confident2 Ų242.6 Ų42.61%0.01222%0.221CC..Hα-helixtrans-64.8-45.1176.7-179.20000110.4R272 L342 E346 A372 S373 L378 L379R272-V375 HydrophobicContact CG-CG2 4.38Å; L342-V375 HydrophobicContact CB-CG1 4.28Å; L342-V375 HydrophobicContact CD2-CG1 4.01Å; L342-V375 WeakPolarHBondContact O-CG1 3.32Å; E346-V375 HydrophobicContact CB-CG1 4.04Å; A372-V375 WeakPolarHBondContact O-CB 3.46Å; A372-V375 PolarHBondContact O-N 3.04Å; S373-V375 VanDerWaalsContact C-N 3.26Å; S373-V375 PolarHBondContact O-N 3.45Å; V375-L378 PolarHBondContact O-N 3.04Å; V375-L379 HydrophobicContact CG1-CD1 4.33Å; V375-L379 WeakPolarHBondContact O-CG 3.41Å; V375-L379 PolarHBondContact O-N 3.29Å
376Y93.8Very high88.8Confident4 Ų444.6 Ų44.62%0.01623%0.229CC..Hα-helixtrans-70.2-32.1178.9-71.7-65.8000113.5E346 A372 S373 L379 T380 C395 A399 F402E346-Y376 HydrophobicContact CG-CE1 4.12Å; E346-Y376 WeakPolarHBondContact CG-OH 3.23Å; E346-Y376 WeakPolarHBondContact OE1-CE1 3.47Å; E346-Y376 PolarHBondContact OE1-OH 2.84Å; A372-Y376 HydrophobicContact CB-CD2 4.35Å; A372-Y376 HydrophobicContact CB-CE2 4.21Å; A372-Y376 WeakPolarHBondContact O-CD2 3.42Å; A372-Y376 PolarHBondContact O-N 3.04Å; A372-Y376 VanDerWaalsContact O-N 3.08Å; S373-Y376 PolarHBondContact O-N 3.43Å; S373-Y376 VanDerWaalsContact O-N 3.14Å; Y376-L379 HydrophobicContact CD1-CD1 3.88Å; Y376-L379 HydrophobicContact CE1-CD1 4.2Å; Y376-L379 PolarHBondContact O-N 3.4Å; Y376-T380 WeakPolarHBondContact O-CB 3.29Å; Y376-T380 PolarHBondContact O-N 2.99Å; Y376-T380 PolarHBondContact O-OG1 3.27Å; Y376-C395 WeakPolarHBondContact CE1-O 3.22Å; Y376-A399 HydrophobicContact CD1-CB 3.71Å; Y376-A399 HydrophobicContact CD2-CB 3.44Å; Y376-A399 VanDerWaalsContact CD2-CB 3.44Å; Y376-A399 HydrophobicContact CE1-CB 3.63Å; Y376-A399 HydrophobicContact CE2-CB 3.33Å; Y376-A399 HydrophobicContact CG-CB 3.63Å; Y376-A399 VanDerWaalsContact CZ-CB 3.43Å; Y376-F402 HydrophobicContact CE2-CD2 4.1Å; Y376-F402 AromaticContact CE2-CE2 3.96Å; Y376-F402 HydrophobicContact CE2-CE2 3.96Å
377D94.6Very high89.3Confident51 Ų5142.2 Ų42.227%0.27323%0.226SC..Hα-helixtrans-65.1-42.8172.1-71-26.2000111.1S373 V374 T380 I381 H408S373-D377 VanDerWaalsContact O-CG 3.28Å; S373-D377 PolarHBondContact O-N 3.23Å; V374-D377 PolarHBondContact O-N 2.85Å; D377-T380 VanDerWaalsContact O-CB 3.32Å; D377-T380 WeakPolarHBondContact O-CB 3.45Å; D377-T380 PolarHBondContact O-N 3.38Å; D377-I381 WeakPolarHBondContact O-CG1 3.42Å; D377-I381 PolarHBondContact O-N 3.29Å; D377-H408 IonicContact OD1-CD2 3.4Å; D377-H408 IonicContact OD1-CE1 3.63Å; D377-H408 PolarHBondContact OD1-CE1 3.32Å; D377-H408 IonicContact OD1-NE2 3.46Å; D377-H408 PolarHBondContact OD1-NE2 3.48Å; D377-H408 IonicContact OD2-NE2 2.65Å
378L95.4Very high89.9Confident17 Ų1742.1 Ų42.19%0.08922%0.223CC..Hα-helixtrans-67.9-37.3175.6-67.4166.1000112.1R272 E276 L279 L342 V374 V375 T380 I381 A382R272-L378 HydrophobicContact CG-CD1 4.02Å; E276-L378 HydrophobicContact CG-CD1 3.39Å; E276-L378 HydrophobicContact CG-CD2 3.78Å; E276-L378 HydrophobicContact CG-CG 4.21Å; L279-L378 HydrophobicContact CD1-CB 4.14Å; L279-L378 HydrophobicContact CD1-CD2 4.06Å; L342-L378 HydrophobicContact CD1-CB 3.75Å; L342-L378 HydrophobicContact CD2-CB 3.59Å; L342-L378 HydrophobicContact CD2-CD1 3.82Å; L342-L378 HydrophobicContact CD2-CG 4.38Å; L342-L378 HydrophobicContact CG-CB 4.34Å; V374-L378 HydrophobicContact CG1-CD1 4Å; V374-L378 WeakPolarHBondContact O-CB 3.36Å; V374-L378 WeakPolarHBondContact O-CD1 3.39Å; V374-L378 WeakPolarHBondContact O-CG 3.37Å; V374-L378 PolarHBondContact O-N 3.12Å; V375-L378 PolarHBondContact O-N 3.04Å; L378-T380 VanDerWaalsContact C-N 3.29Å; L378-T380 PolarHBondContact O-N 3.43Å; L378-I381 HydrophobicContact CD2-CD1 4.46Å; L378-I381 PolarHBondContact O-N 3.37Å; L378-A382 WeakPolarHBondContact O-CB 3.3Å; L378-A382 PolarHBondContact O-N 3.17Å
379L95.9Very high90.4Very high1 Ų145.8 Ų45.81%0.00524%0.235CC..Hα-helixtrans-61.8-39.6171.1-76.2171.4000111.2L339 L342 V375 Y376 A382 L383 C395L339-L379 HydrophobicContact CD2-CD2 3.89Å; L342-L379 HydrophobicContact CB-CD2 3.63Å; L342-L379 HydrophobicContact CB-CG 3.94Å; L342-L379 HydrophobicContact CD1-CD2 3.88Å; L342-L379 HydrophobicContact CD1-CG 4.06Å; L342-L379 HydrophobicContact CG-CD2 4.4Å; V375-L379 HydrophobicContact CG1-CD1 4.33Å; V375-L379 WeakPolarHBondContact O-CG 3.41Å; V375-L379 PolarHBondContact O-N 3.29Å; Y376-L379 HydrophobicContact CD1-CD1 3.88Å; Y376-L379 HydrophobicContact CE1-CD1 4.2Å; Y376-L379 PolarHBondContact O-N 3.4Å; L379-A382 PolarHBondContact O-N 3.3Å; L379-L383 WeakPolarHBondContact O-CB 3.43Å; L379-L383 WeakPolarHBondContact O-CG 3.46Å; L379-L383 PolarHBondContact O-N 3.22Å; L379-C395 HydrophobicContact CD1-CB 4.48Å
380T96.4Very high91Very high25 Ų2549.6 Ų49.615%0.15325%0.252CS..Hα-helixtrans-60.9-44.5174.7-58.30000111.2Y376 D377 L378 G384 L392Y376-T380 WeakPolarHBondContact O-CB 3.29Å; Y376-T380 PolarHBondContact O-N 2.99Å; Y376-T380 PolarHBondContact O-OG1 3.27Å; D377-T380 VanDerWaalsContact O-CB 3.32Å; D377-T380 WeakPolarHBondContact O-CB 3.45Å; D377-T380 PolarHBondContact O-N 3.38Å; L378-T380 VanDerWaalsContact C-N 3.29Å; L378-T380 PolarHBondContact O-N 3.43Å; T380-G384 VanDerWaalsContact O-CA 3.29Å; T380-G384 WeakPolarHBondContact O-CA 3.47Å; T380-G384 PolarHBondContact O-N 2.91Å; T380-L392 HydrophobicContact CG2-CD1 4.45Å; T380-L392 HydrophobicContact CG2-CD2 4.12Å
381I95.7Very high91.5Very high79 Ų7946.9 Ų46.941%0.40524%0.24SC..Hα-helixtrans-65.3-44.5176.7-67.6165.6000111.4D377 L378 R385D377-I381 WeakPolarHBondContact O-CG1 3.42Å; D377-I381 PolarHBondContact O-N 3.29Å; L378-I381 HydrophobicContact CD2-CD1 4.46Å; L378-I381 PolarHBondContact O-N 3.37Å; I381-R385 WeakPolarHBondContact O-CB 3.34Å; I381-R385 VanDerWaalsContact O-CG 3.24Å; I381-R385 WeakPolarHBondContact O-CG 3.5Å; I381-R385 PolarHBondContact O-N 3.06Å; I381-R385 PolarHBondContact O-NE 3.35Å
382A94.1Very high92.4Very high0 Ų045 Ų450%023%0.226CC..Hα-helixtrans-68.9-48.3-176.400000112.5L279 T335 L339 L378 L379 R385L279-A382 HydrophobicContact CD1-CB 4.13Å; L279-A382 HydrophobicContact CD2-CB 3.82Å; T335-A382 HydrophobicContact CG2-CB 4.46Å; L339-A382 HydrophobicContact CD2-CB 3.89Å; L339-A382 HydrophobicContact CG-CB 4.43Å; L378-A382 WeakPolarHBondContact O-CB 3.3Å; L378-A382 PolarHBondContact O-N 3.17Å; L379-A382 PolarHBondContact O-N 3.3Å; A382-R385 WeakPolarHBondContact O-CG 3.31Å
383L93.3Very high93Very high5 Ų544.8 Ų44.83%0.02623%0.225CC..Hα-helixtrans-76.7-38.8-179.8-65.2171.7000111.5L339 L379 R385 R386 G387 Q388 M391 L392L339-L383 HydrophobicContact CD1-CD2 4.1Å; L339-L383 HydrophobicContact CD2-CD2 3.74Å; L339-L383 HydrophobicContact CD2-CG 3.92Å; L379-L383 WeakPolarHBondContact O-CB 3.43Å; L379-L383 WeakPolarHBondContact O-CG 3.46Å; L379-L383 PolarHBondContact O-N 3.22Å; L383-R385 PolarHBondContact O-N 2.97Å; L383-R386 CarbonylContact O-C 3.38Å; L383-R386 PolarHBondContact O-N 3.5Å; L383-G387 PolarHBondContact O-N 3.42Å; L383-Q388 HydrophobicContact CB-CB 4.22Å; L383-Q388 HydrophobicContact CD2-CB 3.99Å; L383-Q388 PolarHBondContact O-N 3.06Å; L383-M391 HydrophobicContact CD1-CG 4.17Å; L383-M391 HydrophobicContact CD1-SD 4.46Å; L383-M391 HydrophobicContact CD2-CG 4.43Å; L383-M391 HydrophobicContact CD2-SD 3.83Å; L383-L392 HydrophobicContact CB-CB 4.01Å; L383-L392 HydrophobicContact CB-CD1 4.49Å; L383-L392 HydrophobicContact CD1-CB 4.02Å; L383-L392 HydrophobicContact CD1-CD1 4.24Å
384G92.9Very high93.3Very high19 Ų1948.4 Ų48.420%0.19624%0.238CC..Hα-helixtrans-62.7-40.6-178.800000113.2T380 R386 G387 Y389T380-G384 VanDerWaalsContact O-CA 3.29Å; T380-G384 WeakPolarHBondContact O-CA 3.47Å; T380-G384 PolarHBondContact O-N 2.91Å; G384-R386 VanDerWaalsContact C-N 3.25Å; G384-R386 PolarHBondContact O-N 2.95Å; G384-G387 PolarHBondContact O-N 3.29Å; G384-Y389 PolarHBondContact O-OH 3.26Å
385R89.5Confident93.5Very high128 Ų12846.3 Ų46.348%0.48323%0.225SC..THydrogen-bonded Turntrans-69.4-20.7177.371178.253.6-179-9.4114L279 I381 A382 L383L279-R385 PolarHBondContact O-NH1 2.99Å; L279-R385 PolarHBondContact O-NH2 2.99Å; I381-R385 WeakPolarHBondContact O-CB 3.34Å; I381-R385 VanDerWaalsContact O-CG 3.24Å; I381-R385 WeakPolarHBondContact O-CG 3.5Å; I381-R385 PolarHBondContact O-N 3.06Å; I381-R385 PolarHBondContact O-NE 3.35Å; A382-R385 WeakPolarHBondContact O-CG 3.31Å; L383-R385 PolarHBondContact O-N 2.97Å
386R89.4Confident93.6Very high93 Ų9346.3 Ų46.335%0.35123%0.225SC..THydrogen-bonded Turntrans-97.66.1175.3-64.1-58-161.8-138.46.3112.6E284 E333 T335 L383 G384 Q388E284-R386 IonicContact OE1-CZ 2.59Å; E284-R386 VanDerWaalsContact OE1-CZ 3.32Å; E284-R386 IonicContact OE1-NH1 2.68Å; E284-R386 PolarHBondContact OE1-NH1 3.12Å; E284-R386 IonicContact OE1-NH2 3.93Å; E284-R386 PolarHBondContact OE1-NH2 3.18Å; E333-R386 IonicContact OE1-NH2 3.43Å; E333-R386 IonicContact OE2-NH2 2.68Å; E333-R386 PolarHBondContact OE2-NH2 3.08Å; T335-R386 HydrophobicContact CG2-CG 4.03Å; T335-R386 PolarHBondContact OG1-NE 2.98Å; T335-R386 PolarHBondContact OG1-NH2 3.44Å; L383-R386 CarbonylContact O-C 3.38Å; L383-R386 PolarHBondContact O-N 3.5Å; G384-R386 VanDerWaalsContact C-N 3.25Å; G384-R386 PolarHBondContact O-N 2.95Å; R386-Q388 HydrophobicContact CB-CG 4.08Å; R386-Q388 PolarHBondContact O-N 3.36Å; R386-Q388 PolarHBondContact O-NE2 2.86Å
387G89.9Confident93.5Very high37 Ų3749 Ų4938%0.38124%0.238SC..THydrogen-bonded Turntrans6815.7-179.100000114.8L383 G384 Y389L383-G387 PolarHBondContact O-N 3.42Å; G384-G387 PolarHBondContact O-N 3.29Å; G387-Y389 WeakPolarHBondContact O-CD2 3.41Å; G387-Y389 PolarHBondContact O-N 3.17Å
388Q93.1Very high93.3Very high105 Ų10551.6 Ų51.649%0.49124%0.244SC..  trans-85.659.1-175.4-62.7-58.4-43.700111.7L383 R386 E390 L392L383-Q388 HydrophobicContact CB-CB 4.22Å; L383-Q388 HydrophobicContact CD2-CB 3.99Å; L383-Q388 PolarHBondContact O-N 3.06Å; R386-Q388 HydrophobicContact CB-CG 4.08Å; R386-Q388 PolarHBondContact O-N 3.36Å; R386-Q388 PolarHBondContact O-NE2 2.86Å; Q388-E390 PolarHBondContact O-N 3.36Å; Q388-L392 WeakPolarHBondContact O-CB 3.26Å; Q388-L392 PolarHBondContact O-N 2.93Å; Q388-L392 VanDerWaalsContact O-N 3.11Å
389Y92.7Very high93Very high91 Ų9150.8 Ų50.836%0.35724%0.24SC..Hα-helixtrans-71.7-27.6-172.5-53.6-61000113.7G384 G387 L392 S393 A419G384-Y389 PolarHBondContact O-OH 3.26Å; G387-Y389 WeakPolarHBondContact O-CD2 3.41Å; G387-Y389 PolarHBondContact O-N 3.17Å; Y389-L392 HydrophobicContact CD1-CD2 4.47Å; Y389-L392 PolarHBondContact O-N 2.95Å; Y389-S393 WeakPolarHBondContact O-CB 3.18Å; Y389-S393 PolarHBondContact O-N 3.38Å; Y389-A419 HydrophobicContact CD1-CB 3.68Å; Y389-A419 HydrophobicContact CD2-CB 3.77Å; Y389-A419 HydrophobicContact CE1-CB 4.14Å; Y389-A419 HydrophobicContact CE2-CB 4.21Å; Y389-A419 HydrophobicContact CG-CB 3.49Å; Y389-A419 VanDerWaalsContact CG-CB 3.49Å
390E93.1Very high92.7Very high125 Ų12552.5 Ų52.558%0.58425%0.249SC*.Hα-helixtrans-64.7-54.3176.7-68.6-168.9170.300111.4Q388 L392 S393 E394 A420Q388-E390 PolarHBondContact O-N 3.36Å; E390-L392 VanDerWaalsContact C-N 3.27Å; E390-L392 PolarHBondContact O-N 3.32Å; E390-S393 PolarHBondContact O-N 3.15Å; E390-S393 VanDerWaalsContact O-N 3.15Å; E390-S393 PolarHBondContact O-OG 3.08Å; E390-E394 PolarHBondContact O-N 2.98Å; E390-A420 HydrophobicContact CG-CB 4.14Å
391M93.1Very high92.1Very high75 Ų7556.1 Ų56.137%0.36926%0.262SS..Hα-helixtrans-60.4-39.1175.4-175-179.7178.400111.3L383 S393 E394 C395L383-M391 HydrophobicContact CD1-CG 4.17Å; L383-M391 HydrophobicContact CD1-SD 4.46Å; L383-M391 HydrophobicContact CD2-CG 4.43Å; L383-M391 HydrophobicContact CD2-SD 3.83Å; M391-S393 VanDerWaalsContact C-N 3.34Å; M391-S393 PolarHBondContact O-N 3.35Å; M391-E394 PolarHBondContact O-N 3.3Å; M391-C395 PolarHBondContact O-N 3.24Å; M391-C395 PolarHBondContact O-SG 2.83Å
392L94.7Very high91.3Very high7 Ų753.5 Ų53.54%0.03725%0.248CC..Hα-helixtrans-60.1-44.2175.7176.857.4000112T380 L383 Q388 Y389 E390 E394 C395 L396T380-L392 HydrophobicContact CG2-CD1 4.45Å; T380-L392 HydrophobicContact CG2-CD2 4.12Å; L383-L392 HydrophobicContact CB-CB 4.01Å; L383-L392 HydrophobicContact CB-CD1 4.49Å; L383-L392 HydrophobicContact CD1-CB 4.02Å; L383-L392 HydrophobicContact CD1-CD1 4.24Å; Q388-L392 WeakPolarHBondContact O-CB 3.26Å; Q388-L392 PolarHBondContact O-N 2.93Å; Q388-L392 VanDerWaalsContact O-N 3.11Å; Y389-L392 HydrophobicContact CD1-CD2 4.47Å; Y389-L392 PolarHBondContact O-N 2.95Å; E390-L392 VanDerWaalsContact C-N 3.27Å; E390-L392 PolarHBondContact O-N 3.32Å; L392-E394 PolarHBondContact O-N 3.13Å; L392-C395 WeakPolarHBondContact O-CB 3.36Å; L392-C395 PolarHBondContact O-N 3.31Å; L392-L396 HydrophobicContact CD1-CD1 3.89Å; L392-L396 HydrophobicContact CD1-CG 4.03Å; L392-L396 HydrophobicContact CG-CD1 4.01Å; L392-L396 WeakPolarHBondContact O-CG 3.44Å; L392-L396 PolarHBondContact O-N 2.87Å
393S95.2Very high90.3Very high0 Ų054.4 Ų54.40%026%0.255CS..Hα-helixtrans-59.7-38177.370.60000111.9Y389 E390 M391 L396 E397 S416 K422Y389-S393 WeakPolarHBondContact O-CB 3.18Å; Y389-S393 PolarHBondContact O-N 3.38Å; E390-S393 PolarHBondContact O-N 3.15Å; E390-S393 VanDerWaalsContact O-N 3.15Å; E390-S393 PolarHBondContact O-OG 3.08Å; M391-S393 VanDerWaalsContact C-N 3.34Å; M391-S393 PolarHBondContact O-N 3.35Å; S393-L396 PolarHBondContact O-N 3.19Å; S393-E397 WeakPolarHBondContact O-CB 3.47Å; S393-E397 VanDerWaalsContact O-CG 3.26Å; S393-E397 WeakPolarHBondContact O-CG 3.39Å; S393-E397 PolarHBondContact O-N 3.11Å; S393-S416 WeakPolarHBondContact CA-OG 3.41Å; S393-K422 PolarHBondContact OG-NZ 3.28Å
394E94.4Very high89.4Confident107 Ų10759.8 Ų59.850%0.528%0.279SS..Hα-helixtrans-69.7-39.8176.2-65.7175.8-174.300112.4E390 M391 L392 E397 R398E390-E394 PolarHBondContact O-N 2.98Å; M391-E394 PolarHBondContact O-N 3.3Å; L392-E394 PolarHBondContact O-N 3.13Å; E394-E397 PolarHBondContact O-N 3.43Å; E394-R398 WeakPolarHBondContact O-CG 3.45Å; E394-R398 PolarHBondContact O-N 2.9Å
395C93.6Very high88.8Confident1 Ų163.9 Ų63.91%0.00729%0.293CS..Hα-helixtrans-59.6-47.6173-68.20000111.6Y376 L379 M391 L392 E397 R398 A399Y376-C395 WeakPolarHBondContact CE1-O 3.22Å; L379-C395 HydrophobicContact CD1-CB 4.48Å; M391-C395 PolarHBondContact O-N 3.24Å; M391-C395 PolarHBondContact O-SG 2.83Å; L392-C395 WeakPolarHBondContact O-CB 3.36Å; L392-C395 PolarHBondContact O-N 3.31Å; C395-E397 VanDerWaalsContact C-N 3.35Å; C395-R398 WeakPolarHBondContact O-CB 3.42Å; C395-R398 PolarHBondContact O-N 3.5Å; C395-R398 PolarHBondContact SG-NH2 3.39Å; C395-A399 PolarHBondContact O-N 2.92Å
396L94.1Very high88.8Confident2 Ų260.4 Ų60.41%0.0128%0.282CS..Hα-helixtrans-69.7-32179.5-68171.9000112.1L392 S393 R398 A399 M400 L409 Q412 L413L392-L396 HydrophobicContact CD1-CD1 3.89Å; L392-L396 HydrophobicContact CD1-CG 4.03Å; L392-L396 HydrophobicContact CG-CD1 4.01Å; L392-L396 WeakPolarHBondContact O-CG 3.44Å; L392-L396 PolarHBondContact O-N 2.87Å; S393-L396 PolarHBondContact O-N 3.19Å; L396-R398 VanDerWaalsContact C-N 3.35Å; L396-R398 PolarHBondContact O-N 2.98Å; L396-A399 WeakPolarHBondContact O-CA 3.42Å; L396-A399 VanDerWaalsContact O-CB 3.25Å; L396-A399 WeakPolarHBondContact O-CB 3.42Å; L396-A399 PolarHBondContact O-N 3.1Å; L396-A399 VanDerWaalsContact O-N 3.13Å; L396-M400 WeakPolarHBondContact O-CG 3.45Å; L396-M400 PolarHBondContact O-N 2.9Å; L396-M400 VanDerWaalsContact O-N 3.12Å; L396-L409 HydrophobicContact CD2-CD1 3.92Å; L396-Q412 HydrophobicContact CD1-CB 3.96Å; L396-Q412 HydrophobicContact CD2-CB 4.38Å; L396-L413 HydrophobicContact CB-CB 4.26Å; L396-L413 HydrophobicContact CB-CD1 3.95Å
397E92.6Very high88.9Confident62 Ų6258.2 Ų58.229%0.2928%0.275SS..Hα-helixtrans-61.6-41.7170.1-79.2173.9-152.200112.2S393 E394 C395 A399 M400 L413 R425S393-E397 WeakPolarHBondContact O-CB 3.47Å; S393-E397 VanDerWaalsContact O-CG 3.26Å; S393-E397 WeakPolarHBondContact O-CG 3.39Å; S393-E397 PolarHBondContact O-N 3.11Å; E394-E397 PolarHBondContact O-N 3.43Å; C395-E397 VanDerWaalsContact C-N 3.35Å; E397-A399 PolarHBondContact O-N 3.46Å; E397-M400 WeakPolarHBondContact O-CB 3.41Å; E397-M400 PolarHBondContact O-N 3.23Å; E397-M400 VanDerWaalsContact O-N 3.17Å; E397-L413 HydrophobicContact CG-CD1 3.73Å; E397-L413 HydrophobicContact CG-CD2 4.25Å; E397-R425 IonicContact OE1-CZ 3.49Å; E397-R425 IonicContact OE1-NH1 3.71Å; E397-R425 PolarHBondContact OE1-NH1 3.18Å; E397-R425 IonicContact OE1-NH2 2.65Å; E397-R425 PolarHBondContact OE1-NH2 3.09Å; E397-R425 IonicContact OE2-CZ 2.75Å; E397-R425 IonicContact OE2-NH1 2.63Å; E397-R425 IonicContact OE2-NH2 3.46Å; E397-R425 PolarHBondContact OE2-NH2 3.4Å
398R90.1Very high89.1Confident104 Ų10459.5 Ų59.539%0.39227%0.271SS..Hα-helixtrans-63.4-33.8173.3-68.5-177.8-65.7137.73.6111.8E346 E394 C395 L396 M400 K401E346-R398 IonicContact OE1-CZ 2.85Å; E346-R398 IonicContact OE1-NE 2.82Å; E346-R398 IonicContact OE1-NH1 3.94Å; E346-R398 PolarHBondContact OE1-NH1 3.49Å; E346-R398 IonicContact OE1-NH2 3.37Å; E346-R398 PolarHBondContact OE1-NH2 2.86Å; E346-R398 IonicContact OE2-CZ 3.03Å; E346-R398 IonicContact OE2-NH1 3.45Å; E346-R398 PolarHBondContact OE2-NH1 3.43Å; E346-R398 IonicContact OE2-NH2 3.12Å; E346-R398 PolarHBondContact OE2-NH2 2.91Å; E346-R398 VanDerWaalsContact OE2-NH2 3.12Å; E394-R398 WeakPolarHBondContact O-CG 3.45Å; E394-R398 PolarHBondContact O-N 2.9Å; C395-R398 WeakPolarHBondContact O-CB 3.42Å; C395-R398 PolarHBondContact O-N 3.5Å; C395-R398 PolarHBondContact SG-NH2 3.39Å; L396-R398 VanDerWaalsContact C-N 3.35Å; L396-R398 PolarHBondContact O-N 2.98Å; R398-M400 VanDerWaalsContact C-N 3.28Å; R398-M400 PolarHBondContact O-N 3.32Å; R398-K401 WeakPolarHBondContact O-CD 3.45Å; R398-K401 WeakPolarHBondContact O-CE 3.36Å; R398-K401 VanDerWaalsContact O-CG 3.28Å; R398-K401 WeakPolarHBondContact O-CG 3.27Å
399A89.8Confident89.1Confident0 Ų054.9 Ų54.90%025%0.25CC..Hα-helixtrans-67-26.9175.900000112.9Y376 C395 L396 E397 K401 F402 L409Y376-A399 HydrophobicContact CD1-CB 3.71Å; Y376-A399 HydrophobicContact CD2-CB 3.44Å; Y376-A399 VanDerWaalsContact CD2-CB 3.44Å; Y376-A399 HydrophobicContact CE1-CB 3.63Å; Y376-A399 HydrophobicContact CE2-CB 3.33Å; Y376-A399 HydrophobicContact CG-CB 3.63Å; Y376-A399 VanDerWaalsContact CZ-CB 3.43Å; C395-A399 PolarHBondContact O-N 2.92Å; L396-A399 WeakPolarHBondContact O-CA 3.42Å; L396-A399 VanDerWaalsContact O-CB 3.25Å; L396-A399 WeakPolarHBondContact O-CB 3.42Å; L396-A399 PolarHBondContact O-N 3.1Å; L396-A399 VanDerWaalsContact O-N 3.13Å; E397-A399 PolarHBondContact O-N 3.46Å; A399-K401 PolarHBondContact O-N 3.05Å; A399-F402 WeakPolarHBondContact O-CB 3.43Å; A399-F402 VanDerWaalsContact O-CD2 3.3Å; A399-F402 WeakPolarHBondContact O-CD2 3.46Å; A399-F402 PolarHBondContact O-N 2.92Å; A399-L409 HydrophobicContact CB-CD1 3.81Å; A399-L409 HydrophobicContact CB-CD2 3.78Å; A399-L409 HydrophobicContact CB-CG 4.28Å; A399-L409 WeakPolarHBondContact O-CD2 3.36Å
400M88.3Confident89.2Confident38 Ų3853.5 Ų53.519%0.18724%0.244CC..THydrogen-bonded Turntrans-59.6-18.8-176.9-66.6-53.9-67.800114.4L396 E397 R398 F402 A403 L409 W410 L413L396-M400 WeakPolarHBondContact O-CG 3.45Å; L396-M400 PolarHBondContact O-N 2.9Å; L396-M400 VanDerWaalsContact O-N 3.12Å; E397-M400 WeakPolarHBondContact O-CB 3.41Å; E397-M400 PolarHBondContact O-N 3.23Å; E397-M400 VanDerWaalsContact O-N 3.17Å; R398-M400 VanDerWaalsContact C-N 3.28Å; R398-M400 PolarHBondContact O-N 3.32Å; M400-F402 PolarHBondContact O-N 3.5Å; M400-A403 HydrophobicContact CE-CB 3.98Å; M400-A403 PolarHBondContact O-N 3.22Å; M400-A403 VanDerWaalsContact O-N 3.13Å; M400-A403 HydrophobicContact SD-CB 4.26Å; M400-L409 HydrophobicContact SD-CD2 3.9Å; M400-L409 HydrophobicContact SD-CG 3.89Å; M400-W410 HydrophobicContact CE-CD2 3.41Å; M400-W410 VanDerWaalsContact CE-CD2 3.41Å; M400-W410 HydrophobicContact CE-CE3 3.93Å; M400-W410 HydrophobicContact CE-CG 3.81Å; M400-W410 HydrophobicContact CE-CH2 3.99Å; M400-W410 HydrophobicContact CE-CZ2 3.51Å; M400-W410 HydrophobicContact CE-CZ3 4.18Å; M400-L413 HydrophobicContact CE-CD2 4.46Å; M400-L413 HydrophobicContact CG-CD2 3.66Å; M400-L413 HydrophobicContact SD-CB 4.49Å; M400-L413 HydrophobicContact SD-CD2 3.78Å
401K84.8Confident89.3Confident100 Ų10049.6 Ų49.644%0.43522%0.224SC..THydrogen-bonded Turntrans-61.4-24.2171.771.4-167.7172.6-178.90113.3N350 L355 R398 A399N350-K401 PolarHBondContact ND2-NZ 3.4Å; N350-K401 WeakPolarHBondContact OD1-CE 3.15Å; N350-K401 PolarHBondContact OD1-NZ 3.4Å; L355-K401 HydrophobicContact CD2-CG 4.42Å; R398-K401 WeakPolarHBondContact O-CD 3.45Å; R398-K401 WeakPolarHBondContact O-CE 3.36Å; R398-K401 VanDerWaalsContact O-CG 3.28Å; R398-K401 WeakPolarHBondContact O-CG 3.27Å; A399-K401 PolarHBondContact O-N 3.05Å
402F79.1Confident89.5Confident24 Ų2448.1 Ų48.111%0.10522%0.216CC..THydrogen-bonded Turntrans-89.1-20.7176.2-58.9-75.6000113N350 A353 L355 L369 A372 Y376 A399 M400 F404N350-F402 VanDerWaalsContact OD1-CE2 3.26Å; N350-F402 WeakPolarHBondContact OD1-CE2 3.25Å; N350-F402 WeakPolarHBondContact OD1-CZ 3.35Å; A353-F402 HydrophobicContact CB-CD1 4.44Å; A353-F402 HydrophobicContact CB-CE1 3.45Å; A353-F402 VanDerWaalsContact CB-CE1 3.45Å; A353-F402 HydrophobicContact CB-CZ 4.08Å; L355-F402 HydrophobicContact CD2-CD1 4.25Å; L355-F402 HydrophobicContact CD2-CE1 4.43Å; L369-F402 HydrophobicContact CD1-CB 4.09Å; A372-F402 HydrophobicContact CB-CD1 4.48Å; A372-F402 HydrophobicContact CB-CD2 4.15Å; A372-F402 HydrophobicContact CB-CE1 4.31Å; A372-F402 HydrophobicContact CB-CE2 4.02Å; A372-F402 HydrophobicContact CB-CG 4.38Å; A372-F402 HydrophobicContact CB-CZ 4.09Å; Y376-F402 HydrophobicContact CE2-CD2 4.1Å; Y376-F402 AromaticContact CE2-CE2 3.96Å; Y376-F402 HydrophobicContact CE2-CE2 3.96Å; A399-F402 WeakPolarHBondContact O-CB 3.43Å; A399-F402 VanDerWaalsContact O-CD2 3.3Å; A399-F402 WeakPolarHBondContact O-CD2 3.46Å; A399-F402 PolarHBondContact O-N 2.92Å; M400-F402 PolarHBondContact O-N 3.5Å; F402-F404 PolarHBondContact O-N 3.13Å
403A72.5Confident89.6Confident19 Ų1948.1 Ų48.116%0.15722%0.216CC..  trans-80115.1-176.500000111.7M400 L409M400-A403 HydrophobicContact CE-CB 3.98Å; M400-A403 PolarHBondContact O-N 3.22Å; M400-A403 VanDerWaalsContact O-N 3.13Å; M400-A403 HydrophobicContact SD-CB 4.26Å; A403-L409 HydrophobicContact CB-CB 4.33Å; A403-L409 HydrophobicContact CB-CD2 3.58Å; A403-L409 HydrophobicContact CB-CG 4.47Å
404F74.8Confident89.6Confident118 Ų11848.1 Ų48.152%0.51822%0.216SC..SBendtrans-117.5102.8162.9-175.7-99.1000108.6F402 E406F402-F404 PolarHBondContact O-N 3.13Å; F404-E406 PolarHBondContact O-N 3.49Å
405E80.4Confident89.8Confident106 Ų10645.6 Ų45.650%0.49521%0.206SC..SBendtrans51.925.6-177.7-57.3-160.4124.400115F407 R435 L436E405-F407 PolarHBondContact O-N 3.16Å; E405-R435 IonicContact OE1-CZ 3.57Å; E405-R435 IonicContact OE1-NH1 2.76Å; E405-R435 PolarHBondContact OE1-NH1 3Å; E405-R435 IonicContact OE1-NH2 2.71Å; E405-R435 PolarHBondContact OE1-NH2 2.86Å; E405-L436 HydrophobicContact CB-CD2 3.85Å; E405-L436 HydrophobicContact CG-CD2 4.23Å
406E88.7Confident89.9Confident54 Ų5445.8 Ų45.825%0.25221%0.207SC..  trans-87.5107.9-179.5-160.4-62.1113.600110.1L369 F404 H408 L409 W410L369-E406 HydrophobicContact CD2-CG 3.99Å; F404-E406 PolarHBondContact O-N 3.49Å; E406-H408 VanDerWaalsContact CD-N 3.29Å; E406-H408 PolarHBondContact O-N 3.5Å; E406-H408 VanDerWaalsContact OE1-CB 3.25Å; E406-H408 WeakPolarHBondContact OE1-CB 3.47Å; E406-H408 PolarHBondContact OE1-N 3.43Å; E406-H408 WeakPolarHBondContact OE2-CA 3.47Å; E406-H408 WeakPolarHBondContact OE2-CB 3.3Å; E406-H408 PolarHBondContact OE2-N 2.94Å; E406-H408 VanDerWaalsContact OE2-N 3.1Å; E406-L409 WeakPolarHBondContact OE2-CB 3.34Å; E406-L409 PolarHBondContact OE2-N 2.9Å; E406-W410 VanDerWaalsContact O-CD1 3.22Å
407F92.5Very high90Very high47 Ų4745.7 Ų45.721%0.20621%0.207CC..Hα-helixtrans-58.8-41.8-172.7172.1-98.5000113.8E405 L409 W410 Y411 C433 L436 K437 I443E405-F407 PolarHBondContact O-N 3.16Å; F407-L409 PolarHBondContact O-N 2.93Å; F407-W410 PolarHBondContact O-N 3.08Å; F407-Y411 HydrophobicContact CE1-CD1 4.16Å; F407-Y411 HydrophobicContact CE1-CG 4.15Å; F407-Y411 HydrophobicContact CE2-CG 4.49Å; F407-Y411 HydrophobicContact CZ-CD1 4.15Å; F407-Y411 HydrophobicContact CZ-CD2 4.16Å; F407-Y411 AromaticContact CZ-CG 3.83Å; F407-Y411 HydrophobicContact CZ-CG 3.83Å; F407-Y411 VanDerWaalsContact O-CB 3.29Å; F407-Y411 WeakPolarHBondContact O-CB 3.31Å; F407-Y411 PolarHBondContact O-N 3.13Å; F407-C433 HydrophobicContact CE2-CB 4.16Å; F407-L436 HydrophobicContact CD2-CB 4.18Å; F407-K437 HydrophobicContact CD1-CD 4.24Å; F407-K437 HydrophobicContact CD2-CB 3.65Å; F407-K437 HydrophobicContact CD2-CD 4.24Å; F407-K437 HydrophobicContact CE1-CD 3.83Å; F407-K437 HydrophobicContact CE2-CB 3.55Å; F407-K437 HydrophobicContact CE2-CD 3.82Å; F407-K437 HydrophobicContact CE2-CG 4.36Å; F407-K437 HydrophobicContact CG-CB 4.38Å; F407-K437 HydrophobicContact CG-CD 4.44Å; F407-K437 HydrophobicContact CZ-CB 4.23Å; F407-K437 HydrophobicContact CZ-CD 3.6Å; F407-I443 HydrophobicContact CE2-CD1 3.58Å; F407-I443 HydrophobicContact CZ-CD1 3.81Å
408H93.1Very high90.2Very high65 Ų6544.5 Ų44.530%0.30120%0.202SC..Hα-helixtrans-59.3-47.9-173.9170.971.9000111.7D377 E406 Y411 Q412D377-H408 IonicContact OD1-CD2 3.4Å; D377-H408 IonicContact OD1-CE1 3.63Å; D377-H408 PolarHBondContact OD1-CE1 3.32Å; D377-H408 IonicContact OD1-NE2 3.46Å; D377-H408 PolarHBondContact OD1-NE2 3.48Å; D377-H408 IonicContact OD2-NE2 2.65Å; E406-H408 VanDerWaalsContact CD-N 3.29Å; E406-H408 PolarHBondContact O-N 3.5Å; E406-H408 VanDerWaalsContact OE1-CB 3.25Å; E406-H408 WeakPolarHBondContact OE1-CB 3.47Å; E406-H408 PolarHBondContact OE1-N 3.43Å; E406-H408 WeakPolarHBondContact OE2-CA 3.47Å; E406-H408 WeakPolarHBondContact OE2-CB 3.3Å; E406-H408 PolarHBondContact OE2-N 2.94Å; E406-H408 VanDerWaalsContact OE2-N 3.1Å; H408-Y411 PolarHBondContact O-N 3.41Å; H408-Q412 PolarHBondContact CE1-NE2 3.45Å; H408-Q412 WeakPolarHBondContact O-CG 3.45Å; H408-Q412 PolarHBondContact O-N 2.84Å
409L92.8Very high90.3Very high8 Ų842 Ų424%0.04220%0.204CC..Hα-helixtrans-68.6-41.1-178-163.467.7000112.4L396 A399 M400 A403 E406 F407 Y411 L413L396-L409 HydrophobicContact CD2-CD1 3.92Å; A399-L409 HydrophobicContact CB-CD1 3.81Å; A399-L409 HydrophobicContact CB-CD2 3.78Å; A399-L409 HydrophobicContact CB-CG 4.28Å; A399-L409 WeakPolarHBondContact O-CD2 3.36Å; M400-L409 HydrophobicContact SD-CD2 3.9Å; M400-L409 HydrophobicContact SD-CG 3.89Å; A403-L409 HydrophobicContact CB-CB 4.33Å; A403-L409 HydrophobicContact CB-CD2 3.58Å; A403-L409 HydrophobicContact CB-CG 4.47Å; E406-L409 WeakPolarHBondContact OE2-CB 3.34Å; E406-L409 PolarHBondContact OE2-N 2.9Å; F407-L409 PolarHBondContact O-N 2.93Å; L409-Y411 VanDerWaalsContact C-N 3.27Å; L409-Y411 PolarHBondContact O-N 3.15Å; L409-L413 WeakPolarHBondContact O-CB 3.39Å; L409-L413 PolarHBondContact O-N 3.47Å
410W95.2Very high90.4Very high61 Ų6142.9 Ų42.923%0.23121%0.21CC..Hα-helixtrans-58.7-42.8172.2-81.894.6000110.9M400 E406 F407 L413 A414 V429 E432 C433 L436M400-W410 HydrophobicContact CE-CD2 3.41Å; M400-W410 VanDerWaalsContact CE-CD2 3.41Å; M400-W410 HydrophobicContact CE-CE3 3.93Å; M400-W410 HydrophobicContact CE-CG 3.81Å; M400-W410 HydrophobicContact CE-CH2 3.99Å; M400-W410 HydrophobicContact CE-CZ2 3.51Å; M400-W410 HydrophobicContact CE-CZ3 4.18Å; E406-W410 VanDerWaalsContact O-CD1 3.22Å; F407-W410 PolarHBondContact O-N 3.08Å; W410-L413 PolarHBondContact O-N 3.47Å; W410-A414 WeakPolarHBondContact O-CB 3.26Å; W410-A414 PolarHBondContact O-N 3.43Å; W410-V429 HydrophobicContact CE3-CG1 3.7Å; W410-V429 HydrophobicContact CZ3-CG1 4.22Å; W410-V429 VanDerWaalsContact O-CG1 3.31Å; W410-V429 WeakPolarHBondContact O-CG1 3.38Å; W410-E432 HydrophobicContact CD2-CB 4.25Å; W410-E432 HydrophobicContact CE3-CB 3.62Å; W410-E432 HydrophobicContact CE3-CG 4.17Å; W410-E432 HydrophobicContact CH2-CB 4.32Å; W410-E432 HydrophobicContact CH2-CG 4.04Å; W410-E432 HydrophobicContact CZ3-CB 3.67Å; W410-E432 HydrophobicContact CZ3-CG 3.67Å; W410-C433 VanDerWaalsContact C-SG 3.52Å; W410-L436 HydrophobicContact CB-CD1 4.23Å; W410-L436 HydrophobicContact CG-CD1 3.92Å
411Y96.4Very high90.4Very high43 Ų4343.7 Ų43.717%0.16923%0.228CC..Hα-helixtrans-70-45.3-179.2-168.5-128.2000112.5F407 H408 L409 L413 A414 L415 I443 L446F407-Y411 HydrophobicContact CE1-CD1 4.16Å; F407-Y411 HydrophobicContact CE1-CG 4.15Å; F407-Y411 HydrophobicContact CE2-CG 4.49Å; F407-Y411 HydrophobicContact CZ-CD1 4.15Å; F407-Y411 HydrophobicContact CZ-CD2 4.16Å; F407-Y411 AromaticContact CZ-CG 3.83Å; F407-Y411 HydrophobicContact CZ-CG 3.83Å; F407-Y411 VanDerWaalsContact O-CB 3.29Å; F407-Y411 WeakPolarHBondContact O-CB 3.31Å; F407-Y411 PolarHBondContact O-N 3.13Å; H408-Y411 PolarHBondContact O-N 3.41Å; L409-Y411 VanDerWaalsContact C-N 3.27Å; L409-Y411 PolarHBondContact O-N 3.15Å; Y411-L413 VanDerWaalsContact C-N 3.3Å; Y411-L413 PolarHBondContact O-N 3.12Å; Y411-A414 WeakPolarHBondContact O-CB 3.44Å; Y411-A414 PolarHBondContact O-N 3.49Å; Y411-A414 VanDerWaalsContact O-N 3.16Å; Y411-L415 HydrophobicContact CD1-CD1 4.1Å; Y411-L415 HydrophobicContact CE1-CD1 3.79Å; Y411-L415 HydrophobicContact CE1-CG 4.48Å; Y411-L415 HydrophobicContact CE2-CD1 4.44Å; Y411-L415 HydrophobicContact CE2-CD2 4.21Å; Y411-L415 HydrophobicContact CE2-CG 4.27Å; Y411-L415 WeakPolarHBondContact O-CG 3.48Å; Y411-L415 PolarHBondContact O-N 3.19Å; Y411-I443 HydrophobicContact CE2-CG1 4.08Å; Y411-L446 HydrophobicContact CE2-CD1 4.44Å
412Q96.1Very high90.9Very high44 Ų4441.5 Ų41.521%0.20622%0.219CC..Hα-helixtrans-60-41174.3-64.6-51-31.300111.8L396 H408 A414 L415 S416L396-Q412 HydrophobicContact CD1-CB 3.96Å; L396-Q412 HydrophobicContact CD2-CB 4.38Å; H408-Q412 PolarHBondContact CE1-NE2 3.45Å; H408-Q412 WeakPolarHBondContact O-CG 3.45Å; H408-Q412 PolarHBondContact O-N 2.84Å; Q412-A414 PolarHBondContact O-N 2.94Å; Q412-L415 PolarHBondContact O-N 3.21Å; Q412-S416 WeakPolarHBondContact O-CB 3.45Å; Q412-S416 PolarHBondContact O-N 3.15Å; Q412-S416 PolarHBondContact O-OG 3.49Å
413L96.4Very high91.6Very high8 Ų841 Ų414%0.04222%0.218CC..Hα-helixtrans-61.6-45.517517759.2000111.1L396 E397 M400 L409 W410 Y411 L415 S416 L417 V429L396-L413 HydrophobicContact CB-CB 4.26Å; L396-L413 HydrophobicContact CB-CD1 3.95Å; E397-L413 HydrophobicContact CG-CD1 3.73Å; E397-L413 HydrophobicContact CG-CD2 4.25Å; M400-L413 HydrophobicContact CE-CD2 4.46Å; M400-L413 HydrophobicContact CG-CD2 3.66Å; M400-L413 HydrophobicContact SD-CB 4.49Å; M400-L413 HydrophobicContact SD-CD2 3.78Å; L409-L413 WeakPolarHBondContact O-CB 3.39Å; L409-L413 PolarHBondContact O-N 3.47Å; W410-L413 PolarHBondContact O-N 3.47Å; Y411-L413 VanDerWaalsContact C-N 3.3Å; Y411-L413 PolarHBondContact O-N 3.12Å; L413-L415 PolarHBondContact O-N 3.47Å; L413-S416 PolarHBondContact O-N 3.14Å; L413-S416 PolarHBondContact O-OG 2.79Å; L413-L417 HydrophobicContact CD1-CD1 3.95Å; L413-L417 HydrophobicContact CD1-CG 3.95Å; L413-L417 HydrophobicContact CG-CD1 3.93Å; L413-L417 HydrophobicContact CG-CG 4.39Å; L413-L417 WeakPolarHBondContact O-CB 3.48Å; L413-L417 VanDerWaalsContact O-CG 3.31Å; L413-L417 WeakPolarHBondContact O-CG 3.38Å; L413-L417 PolarHBondContact O-N 2.94Å; L413-V429 HydrophobicContact CB-CG1 4.43Å; L413-V429 HydrophobicContact CD2-CG1 4.35Å; L413-V429 HydrophobicContact CD2-CG2 4.43Å; L413-V429 HydrophobicContact CG-CG1 4.28Å
414A96.8Very high92.7Very high0 Ų041.8 Ų41.80%023%0.225CC..Hα-helixtrans-59.1-44.8177.900000112.4W410 Y411 Q412 L417 M418 V429 L430W410-A414 WeakPolarHBondContact O-CB 3.26Å; W410-A414 PolarHBondContact O-N 3.43Å; Y411-A414 WeakPolarHBondContact O-CB 3.44Å; Y411-A414 PolarHBondContact O-N 3.49Å; Y411-A414 VanDerWaalsContact O-N 3.16Å; Q412-A414 PolarHBondContact O-N 2.94Å; A414-L417 PolarHBondContact O-N 3.28Å; A414-M418 WeakPolarHBondContact O-CB 3.37Å; A414-M418 PolarHBondContact O-N 2.95Å; A414-V429 HydrophobicContact CB-CB 4.13Å; A414-V429 HydrophobicContact CB-CG1 3.74Å; A414-L430 HydrophobicContact CB-CD2 3.68Å; A414-L430 HydrophobicContact CB-CG 3.95Å
415L97.4Very high93.7Very high54 Ų5441.4 Ų41.428%0.28322%0.22SC..Hα-helixtrans-66.1-42.7177.8-65.1177.7000111.9Y411 Q412 L413 M418 A419 L446Y411-L415 HydrophobicContact CD1-CD1 4.1Å; Y411-L415 HydrophobicContact CE1-CD1 3.79Å; Y411-L415 HydrophobicContact CE1-CG 4.48Å; Y411-L415 HydrophobicContact CE2-CD1 4.44Å; Y411-L415 HydrophobicContact CE2-CD2 4.21Å; Y411-L415 HydrophobicContact CE2-CG 4.27Å; Y411-L415 WeakPolarHBondContact O-CG 3.48Å; Y411-L415 PolarHBondContact O-N 3.19Å; Q412-L415 PolarHBondContact O-N 3.21Å; L413-L415 PolarHBondContact O-N 3.47Å; L415-M418 WeakPolarHBondContact O-CB 3.22Å; L415-M418 PolarHBondContact O-N 3.15Å; L415-A419 WeakPolarHBondContact O-CB 3.49Å; L415-A419 PolarHBondContact O-N 2.9Å; L415-L446 HydrophobicContact CD2-CD1 3.82Å
416S96.9Very high94.5Very high4 Ų436.3 Ų36.33%0.02820%0.196CC..Hα-helixtrans-64.1-40.7176.8720000112.5S393 Q412 L413 M418 A419 A420S393-S416 WeakPolarHBondContact CA-OG 3.41Å; Q412-S416 WeakPolarHBondContact O-CB 3.45Å; Q412-S416 PolarHBondContact O-N 3.15Å; Q412-S416 PolarHBondContact O-OG 3.49Å; L413-S416 PolarHBondContact O-N 3.14Å; L413-S416 PolarHBondContact O-OG 2.79Å; S416-M418 VanDerWaalsContact C-N 3.33Å; S416-M418 PolarHBondContact O-N 3.45Å; S416-A419 PolarHBondContact O-N 3.34Å; S416-A420 VanDerWaalsContact O-CB 3.23Å; S416-A420 WeakPolarHBondContact O-CB 3.49Å; S416-A420 PolarHBondContact O-N 3.37Å
417L96.3Very high94.9Very high1 Ų133.8 Ų33.81%0.00519%0.185CC..Hα-helixtrans-65.5-37.1175.5-73170.9000111.9L413 A414 G421 K422 R425 A426 V429L413-L417 HydrophobicContact CD1-CD1 3.95Å; L413-L417 HydrophobicContact CD1-CG 3.95Å; L413-L417 HydrophobicContact CG-CD1 3.93Å; L413-L417 HydrophobicContact CG-CG 4.39Å; L413-L417 WeakPolarHBondContact O-CB 3.48Å; L413-L417 VanDerWaalsContact O-CG 3.31Å; L413-L417 WeakPolarHBondContact O-CG 3.38Å; L413-L417 PolarHBondContact O-N 2.94Å; A414-L417 PolarHBondContact O-N 3.28Å; L417-G421 PolarHBondContact O-N 3.21Å; L417-K422 HydrophobicContact CB-CB 4.46Å; L417-K422 HydrophobicContact CD2-CB 3.98Å; L417-K422 HydrophobicContact CD2-CD 3.71Å; L417-K422 HydrophobicContact CD2-CG 4.47Å; L417-K422 PolarHBondContact O-N 3.49Å; L417-R425 HydrophobicContact CD1-CB 4.16Å; L417-R425 HydrophobicContact CD2-CB 4.43Å; L417-A426 HydrophobicContact CB-CB 3.81Å; L417-V429 HydrophobicContact CD1-CB 4.45Å; L417-V429 HydrophobicContact CD1-CG2 3.69Å
418M95.3Very high95.1Very high37 Ų3738.3 Ų38.318%0.18220%0.204CC..Hα-helixtrans-63.5-49.2174.2-176.4178.1-62.800111.1A414 L415 S416 A420 G421 A426 L430 L446 L450A414-M418 WeakPolarHBondContact O-CB 3.37Å; A414-M418 PolarHBondContact O-N 2.95Å; L415-M418 WeakPolarHBondContact O-CB 3.22Å; L415-M418 PolarHBondContact O-N 3.15Å; S416-M418 VanDerWaalsContact C-N 3.33Å; S416-M418 PolarHBondContact O-N 3.45Å; M418-A420 VanDerWaalsContact C-N 3.3Å; M418-A420 PolarHBondContact O-N 3.47Å; M418-G421 PolarHBondContact O-N 2.87Å; M418-G421 VanDerWaalsContact O-N 3.11Å; M418-A426 HydrophobicContact CB-CB 4.28Å; M418-L430 HydrophobicContact CE-CD1 3.81Å; M418-L446 HydrophobicContact CE-CB 3.64Å; M418-L446 HydrophobicContact CE-CD1 4.39Å; M418-L446 HydrophobicContact CE-CD2 4.05Å; M418-L446 HydrophobicContact CE-CG 4.23Å; M418-L446 HydrophobicContact SD-CD2 3.95Å; M418-L450 HydrophobicContact CE-CD1 3.6Å; M418-L450 HydrophobicContact CE-CG 3.86Å; M418-L450 HydrophobicContact CG-CD1 4.21Å; M418-L450 HydrophobicContact CG-CD2 4Å; M418-L450 HydrophobicContact CG-CG 4.34Å
419A93.2Very high95.2Very high52 Ų5236 Ų3643%0.4320%0.195SC..Hα-helixtrans-66.1-31.717900000112.7Y389 L415 S416 G421Y389-A419 HydrophobicContact CD1-CB 3.68Å; Y389-A419 HydrophobicContact CD2-CB 3.77Å; Y389-A419 HydrophobicContact CE1-CB 4.14Å; Y389-A419 HydrophobicContact CE2-CB 4.21Å; Y389-A419 HydrophobicContact CG-CB 3.49Å; Y389-A419 VanDerWaalsContact CG-CB 3.49Å; L415-A419 WeakPolarHBondContact O-CB 3.49Å; L415-A419 PolarHBondContact O-N 2.9Å; S416-A419 PolarHBondContact O-N 3.34Å; A419-G421 PolarHBondContact O-N 3.44Å
420A91.1Very high95.4Very high17 Ų1735.7 Ų35.714%0.1419%0.193CC..THydrogen-bonded Turntrans-76.11.5173.500000114.1E390 S416 M418 K422E390-A420 HydrophobicContact CG-CB 4.14Å; S416-A420 VanDerWaalsContact O-CB 3.23Å; S416-A420 WeakPolarHBondContact O-CB 3.49Å; S416-A420 PolarHBondContact O-N 3.37Å; M418-A420 VanDerWaalsContact C-N 3.3Å; M418-A420 PolarHBondContact O-N 3.47Å; A420-K422 HydrophobicContact CB-CD 4.45Å; A420-K422 HydrophobicContact CB-CG 4.41Å; A420-K422 PolarHBondContact O-N 2.93Å
421G89.6Confident95.5Very high55 Ų5536.8 Ų36.857%0.56720%0.199SC*.THydrogen-bonded Turntrans71.87.7-178.200000115L417 M418 A419 S423L417-G421 PolarHBondContact O-N 3.21Å; M418-G421 PolarHBondContact O-N 2.87Å; M418-G421 VanDerWaalsContact O-N 3.11Å; A419-G421 PolarHBondContact O-N 3.44Å; G421-S423 PolarHBondContact O-N 2.72Å; G421-S423 PolarHBondContact O-OG 3.36Å
422K93.8Very high95.4Very high55 Ų5538.1 Ų38.124%0.23921%0.207CC..  trans-80.554.5177.2-65.2174.6-176.8168.80110.8S393 L417 A420 A424 R425 A426S393-K422 PolarHBondContact OG-NZ 3.28Å; L417-K422 HydrophobicContact CB-CB 4.46Å; L417-K422 HydrophobicContact CD2-CB 3.98Å; L417-K422 HydrophobicContact CD2-CD 3.71Å; L417-K422 HydrophobicContact CD2-CG 4.47Å; L417-K422 PolarHBondContact O-N 3.49Å; A420-K422 HydrophobicContact CB-CD 4.45Å; A420-K422 HydrophobicContact CB-CG 4.41Å; A420-K422 PolarHBondContact O-N 2.93Å; K422-A424 PolarHBondContact O-N 2.62Å; K422-R425 PolarHBondContact O-N 2.83Å; K422-R425 VanDerWaalsContact O-N 3.11Å; K422-A426 PolarHBondContact O-N 3.42Å
423S94.4Very high95.4Very high13 Ų1336 Ų369%0.09120%0.197CC..Hα-helixtrans-54.5-45.2-166.7-52.50000114.2G421 R425 A426 V427 P454G421-S423 PolarHBondContact O-N 2.72Å; G421-S423 PolarHBondContact O-OG 3.36Å; S423-R425 VanDerWaalsContact C-N 3.32Å; S423-R425 PolarHBondContact O-N 2.87Å; S423-A426 PolarHBondContact O-N 3.11Å; S423-V427 WeakPolarHBondContact O-CG2 3.49Å; S423-V427 PolarHBondContact O-N 3.47Å; S423-P454 WeakPolarHBondContact OG-CG 3.47Å
424A95Very high95.4Very high36 Ų3636.5 Ų36.530%0.29820%0.2SC..Hα-helixtrans-64.1-36.5-17800000112.7K422 L455 W457K422-A424 PolarHBondContact O-N 2.62Å; A424-L455 HydrophobicContact CB-CD2 3.9Å; A424-W457 HydrophobicContact CB-CH2 3.79Å; A424-W457 HydrophobicContact CB-CZ2 4.21Å
425R96.1Very high95.3Very high109 Ų10942.6 Ų42.641%0.41122%0.223SC..Hα-helixtrans-72.6-43.8175.7-66-179.867.3-170.50.8110.3E397 L417 K422 S423 V427 K428 V429E397-R425 IonicContact OE1-CZ 3.49Å; E397-R425 IonicContact OE1-NH1 3.71Å; E397-R425 PolarHBondContact OE1-NH1 3.18Å; E397-R425 IonicContact OE1-NH2 2.65Å; E397-R425 PolarHBondContact OE1-NH2 3.09Å; E397-R425 IonicContact OE2-CZ 2.75Å; E397-R425 IonicContact OE2-NH1 2.63Å; E397-R425 IonicContact OE2-NH2 3.46Å; E397-R425 PolarHBondContact OE2-NH2 3.4Å; L417-R425 HydrophobicContact CD1-CB 4.16Å; L417-R425 HydrophobicContact CD2-CB 4.43Å; K422-R425 PolarHBondContact O-N 2.83Å; K422-R425 VanDerWaalsContact O-N 3.11Å; S423-R425 VanDerWaalsContact C-N 3.32Å; S423-R425 PolarHBondContact O-N 2.87Å; R425-V427 VanDerWaalsContact C-N 3.31Å; R425-V427 PolarHBondContact O-N 3.23Å; R425-K428 WeakPolarHBondContact O-CB 3.28Å; R425-K428 PolarHBondContact O-N 3.35Å; R425-V429 WeakPolarHBondContact O-CG2 3.48Å; R425-V429 PolarHBondContact O-N 3Å
426A96.9Very high95.2Very high0 Ų042 Ų420%022%0.22CC..Hα-helixtrans-55.1-44.9176.800000111.9L417 M418 K422 S423 K428 V429 L430 L450L417-A426 HydrophobicContact CB-CB 3.81Å; M418-A426 HydrophobicContact CB-CB 4.28Å; K422-A426 PolarHBondContact O-N 3.42Å; S423-A426 PolarHBondContact O-N 3.11Å; A426-K428 VanDerWaalsContact C-N 3.3Å; A426-K428 PolarHBondContact O-N 3.24Å; A426-V429 PolarHBondContact O-N 2.91Å; A426-L430 WeakPolarHBondContact O-CB 3.46Å; A426-L430 VanDerWaalsContact O-CG 3.26Å; A426-L430 WeakPolarHBondContact O-CG 3.25Å; A426-L430 PolarHBondContact O-N 3.4Å; A426-L450 HydrophobicContact CB-CD1 3.56Å
427V97.3Very high95Very high1 Ų145.9 Ų45.91%0.00624%0.236CC..Hα-helixtrans-58.6-39.8176.11730000112.3S423 R425 L430 K431 L450 L455 W457 F464S423-V427 WeakPolarHBondContact O-CG2 3.49Å; S423-V427 PolarHBondContact O-N 3.47Å; R425-V427 VanDerWaalsContact C-N 3.31Å; R425-V427 PolarHBondContact O-N 3.23Å; V427-L430 PolarHBondContact O-N 3Å; V427-K431 WeakPolarHBondContact O-CG 3.49Å; V427-K431 PolarHBondContact O-N 3.45Å; V427-L450 HydrophobicContact CG2-CB 3.72Å; V427-L450 HydrophobicContact CG2-CD1 3.91Å; V427-L455 HydrophobicContact CG2-CD1 3.79Å; V427-W457 HydrophobicContact CB-CZ3 4.36Å; V427-W457 HydrophobicContact CG1-CE3 4.49Å; V427-W457 HydrophobicContact CG1-CZ3 4.22Å; V427-F464 HydrophobicContact CG1-CE2 4.02Å; V427-F464 HydrophobicContact CG1-CZ 4.27Å
428K96.2Very high94.8Very high142 Ų14249.5 Ų49.562%0.61726%0.259SS*.Hα-helixtrans-65.7-44.2177.4-66.3176.2-178.8-1790111.8R425 A426 K431 E432R425-K428 WeakPolarHBondContact O-CB 3.28Å; R425-K428 PolarHBondContact O-N 3.35Å; A426-K428 VanDerWaalsContact C-N 3.3Å; A426-K428 PolarHBondContact O-N 3.24Å; K428-K431 WeakPolarHBondContact O-CB 3.4Å; K428-K431 PolarHBondContact O-N 2.58Å; K428-E432 PolarHBondContact O-N 2.88Å
429V96.5Very high94.4Very high17 Ų1753.4 Ų53.410%0.10328%0.281CS..Hα-helixtrans-66.6-39.3177.6-176.20000110.5W410 L413 A414 L417 R425 A426 K431 E432 C433W410-V429 HydrophobicContact CE3-CG1 3.7Å; W410-V429 HydrophobicContact CZ3-CG1 4.22Å; W410-V429 VanDerWaalsContact O-CG1 3.31Å; W410-V429 WeakPolarHBondContact O-CG1 3.38Å; L413-V429 HydrophobicContact CB-CG1 4.43Å; L413-V429 HydrophobicContact CD2-CG1 4.35Å; L413-V429 HydrophobicContact CD2-CG2 4.43Å; L413-V429 HydrophobicContact CG-CG1 4.28Å; A414-V429 HydrophobicContact CB-CB 4.13Å; A414-V429 HydrophobicContact CB-CG1 3.74Å; L417-V429 HydrophobicContact CD1-CB 4.45Å; L417-V429 HydrophobicContact CD1-CG2 3.69Å; R425-V429 WeakPolarHBondContact O-CG2 3.48Å; R425-V429 PolarHBondContact O-N 3Å; A426-V429 PolarHBondContact O-N 2.91Å; V429-K431 VanDerWaalsContact C-N 3.3Å; V429-K431 PolarHBondContact O-N 3.49Å; V429-E432 WeakPolarHBondContact O-CB 3.26Å; V429-E432 PolarHBondContact O-N 2.95Å; V429-E432 VanDerWaalsContact O-N 3.08Å; V429-C433 PolarHBondContact O-N 3.03Å; V429-C433 PolarHBondContact O-SG 3.28Å
430L97Very high94.4Very high0 Ų052.2 Ų52.20%027%0.267CS..Hα-helixtrans-61.1-35.1174.1-71.7169.9000112.7A414 M418 A426 V427 E432 C433 I434 I443 L446 A447 L450A414-L430 HydrophobicContact CB-CD2 3.68Å; A414-L430 HydrophobicContact CB-CG 3.95Å; M418-L430 HydrophobicContact CE-CD1 3.81Å; A426-L430 WeakPolarHBondContact O-CB 3.46Å; A426-L430 VanDerWaalsContact O-CG 3.26Å; A426-L430 WeakPolarHBondContact O-CG 3.25Å; A426-L430 PolarHBondContact O-N 3.4Å; V427-L430 PolarHBondContact O-N 3Å; L430-E432 VanDerWaalsContact C-N 3.3Å; L430-E432 PolarHBondContact O-N 3.01Å; L430-C433 WeakPolarHBondContact O-CB 3.43Å; L430-C433 PolarHBondContact O-N 2.86Å; L430-I434 VanDerWaalsContact O-CG1 3.27Å; L430-I434 WeakPolarHBondContact O-CG1 3.31Å; L430-I434 PolarHBondContact O-N 3.31Å; L430-I443 HydrophobicContact CB-CG2 4.25Å; L430-I443 HydrophobicContact CD2-CG2 3.62Å; L430-L446 HydrophobicContact CD1-CB 4.23Å; L430-A447 HydrophobicContact CB-CB 4.39Å; L430-A447 HydrophobicContact CD1-CB 4.01Å; L430-L450 HydrophobicContact CD1-CD1 4.24Å
431K96.4Very high94.5Very high85 Ų8551.9 Ų51.937%0.3726%0.264SS..Hα-helixtrans-59.9-40.3172.8-73.8178.7176.9-171.60112V427 K428 V429 I434 R435 E460 F464V427-K431 WeakPolarHBondContact O-CG 3.49Å; V427-K431 PolarHBondContact O-N 3.45Å; K428-K431 WeakPolarHBondContact O-CB 3.4Å; K428-K431 PolarHBondContact O-N 2.58Å; V429-K431 VanDerWaalsContact C-N 3.3Å; V429-K431 PolarHBondContact O-N 3.49Å; K431-I434 PolarHBondContact O-N 3.28Å; K431-R435 PolarHBondContact O-N 3.43Å; K431-R435 VanDerWaalsContact O-N 3.07Å; K431-E460 WeakPolarHBondContact CE-OE2 3.37Å; K431-E460 IonicContact NZ-OE2 3.65Å; K431-E460 PolarHBondContact NZ-OE2 3.2Å; K431-F464 HydrophobicContact CD-CZ 4.17Å; K431-F464 HydrophobicContact CG-CE1 4.02Å; K431-F464 HydrophobicContact CG-CZ 3.64Å
432E95.3Very high94.7Very high70 Ų7051.6 Ų51.633%0.32725%0.251SS..Hα-helixtrans-68.2-39.8173.7-66.5-55.8138.600111.7W410 K428 V429 L430 I434 R435 L436W410-E432 HydrophobicContact CD2-CB 4.25Å; W410-E432 HydrophobicContact CE3-CB 3.62Å; W410-E432 HydrophobicContact CE3-CG 4.17Å; W410-E432 HydrophobicContact CH2-CB 4.32Å; W410-E432 HydrophobicContact CH2-CG 4.04Å; W410-E432 HydrophobicContact CZ3-CB 3.67Å; W410-E432 HydrophobicContact CZ3-CG 3.67Å; K428-E432 PolarHBondContact O-N 2.88Å; V429-E432 WeakPolarHBondContact O-CB 3.26Å; V429-E432 PolarHBondContact O-N 2.95Å; V429-E432 VanDerWaalsContact O-N 3.08Å; L430-E432 VanDerWaalsContact C-N 3.3Å; L430-E432 PolarHBondContact O-N 3.01Å; E432-I434 VanDerWaalsContact C-N 3.31Å; E432-I434 PolarHBondContact O-N 3.2Å; E432-R435 WeakPolarHBondContact O-CB 3.45Å; E432-R435 PolarHBondContact O-N 3.39Å; E432-R435 VanDerWaalsContact O-N 3.13Å; E432-R435 IonicContact OE2-CZ 2.81Å; E432-R435 IonicContact OE2-NE 3.45Å; E432-R435 PolarHBondContact OE2-NE 3.35Å; E432-R435 IonicContact OE2-NH2 3.84Å; E432-L436 WeakPolarHBondContact O-CG 3.42Å; E432-L436 PolarHBondContact O-N 2.79Å
433C96.4Very high94.8Very high0 Ų049 Ų490%024%0.24CC..Hα-helixtrans-60.2-40.2173.9-610000112.3F407 W410 V429 L430 R435 L436 K437 I443F407-C433 HydrophobicContact CE2-CB 4.16Å; W410-C433 VanDerWaalsContact C-SG 3.52Å; V429-C433 PolarHBondContact O-N 3.03Å; V429-C433 PolarHBondContact O-SG 3.28Å; L430-C433 WeakPolarHBondContact O-CB 3.43Å; L430-C433 PolarHBondContact O-N 2.86Å; C433-R435 VanDerWaalsContact C-N 3.34Å; C433-L436 PolarHBondContact O-N 3.23Å; C433-K437 PolarHBondContact O-N 2.97Å; C433-I443 HydrophobicContact CB-CD1 4.18Å; C433-I443 HydrophobicContact CB-CG2 3.67Å
434I95.3Very high94.9Very high19 Ų1948.4 Ų48.410%0.09724%0.236CC..Hα-helixtrans-62.2-42174.3-68.7163.6000110.5L430 K431 E432 L436 K437 P438 I443 P444 F464 M467L430-I434 VanDerWaalsContact O-CG1 3.27Å; L430-I434 WeakPolarHBondContact O-CG1 3.31Å; L430-I434 PolarHBondContact O-N 3.31Å; K431-I434 PolarHBondContact O-N 3.28Å; E432-I434 VanDerWaalsContact C-N 3.31Å; E432-I434 PolarHBondContact O-N 3.2Å; I434-L436 VanDerWaalsContact C-N 3.34Å; I434-L436 PolarHBondContact O-N 3.43Å; I434-K437 CarbonylContact O-C 3.58Å; I434-P438 VanDerWaalsContact O-CA 3.31Å; I434-P438 WeakPolarHBondContact O-CA 3.43Å; I434-I443 HydrophobicContact CD1-CG2 4.44Å; I434-I443 HydrophobicContact CG1-CB 4.08Å; I434-I443 HydrophobicContact CG1-CG2 3.68Å; I434-P444 HydrophobicContact CD1-CB 3.93Å; I434-P444 HydrophobicContact CG1-CB 4.48Å; I434-F464 HydrophobicContact CD1-CD1 3.82Å; I434-F464 HydrophobicContact CD1-CE1 3.55Å; I434-M467 HydrophobicContact CD1-SD 4.48Å; I434-M467 HydrophobicContact CG2-CE 4.39Å; I434-M467 HydrophobicContact CG2-SD 3.66Å
435R95.3Very high94.9Very high128 Ų12847.8 Ų47.848%0.48323%0.227SC..Hα-helixtrans-62.1-42176.2-173.9-170.466.881.2-3.8111.8E405 K431 E432 C433E405-R435 IonicContact OE1-CZ 3.57Å; E405-R435 IonicContact OE1-NH1 2.76Å; E405-R435 PolarHBondContact OE1-NH1 3Å; E405-R435 IonicContact OE1-NH2 2.71Å; E405-R435 PolarHBondContact OE1-NH2 2.86Å; K431-R435 PolarHBondContact O-N 3.43Å; K431-R435 VanDerWaalsContact O-N 3.07Å; E432-R435 WeakPolarHBondContact O-CB 3.45Å; E432-R435 PolarHBondContact O-N 3.39Å; E432-R435 VanDerWaalsContact O-N 3.13Å; E432-R435 IonicContact OE2-CZ 2.81Å; E432-R435 IonicContact OE2-NE 3.45Å; E432-R435 PolarHBondContact OE2-NE 3.35Å; E432-R435 IonicContact OE2-NH2 3.84Å; C433-R435 VanDerWaalsContact C-N 3.34Å
436L94.4Very high94.9Very high41 Ų4144.2 Ų44.222%0.21522%0.216CC..Hα-helixtrans-73.7-35.1-178.9-67.8176.6000112.8E405 F407 W410 E432 C433 I434E405-L436 HydrophobicContact CB-CD2 3.85Å; E405-L436 HydrophobicContact CG-CD2 4.23Å; F407-L436 HydrophobicContact CD2-CB 4.18Å; W410-L436 HydrophobicContact CB-CD1 4.23Å; W410-L436 HydrophobicContact CG-CD1 3.92Å; E432-L436 WeakPolarHBondContact O-CG 3.42Å; E432-L436 PolarHBondContact O-N 2.79Å; C433-L436 PolarHBondContact O-N 3.23Å; I434-L436 VanDerWaalsContact C-N 3.34Å; I434-L436 PolarHBondContact O-N 3.43Å
437K93.4Very high94.9Very high85 Ų8544.2 Ų44.237%0.3722%0.216SC..  trans-137.679.5-178-165.4-175.3178.3-158.60110.9F407 C433 I434 D439 D440 I443F407-K437 HydrophobicContact CD1-CD 4.24Å; F407-K437 HydrophobicContact CD2-CB 3.65Å; F407-K437 HydrophobicContact CD2-CD 4.24Å; F407-K437 HydrophobicContact CE1-CD 3.83Å; F407-K437 HydrophobicContact CE2-CB 3.55Å; F407-K437 HydrophobicContact CE2-CD 3.82Å; F407-K437 HydrophobicContact CE2-CG 4.36Å; F407-K437 HydrophobicContact CG-CB 4.38Å; F407-K437 HydrophobicContact CG-CD 4.44Å; F407-K437 HydrophobicContact CZ-CB 4.23Å; F407-K437 HydrophobicContact CZ-CD 3.6Å; C433-K437 PolarHBondContact O-N 2.97Å; I434-K437 CarbonylContact O-C 3.58Å; K437-D439 PolarHBondContact O-N 3.47Å; K437-D440 HydrophobicContact CD-CB 4Å; K437-D440 HydrophobicContact CG-CB 4.21Å; K437-D440 IonicContact NZ-OD2 2.66Å; K437-D440 PolarHBondContact NZ-OD2 3.03Å; K437-D440 PolarHBondContact O-N 3.28Å; K437-I443 HydrophobicContact CB-CD1 4.42Å
438P91.2Very high94.9Very high77 Ų7744.2 Ų44.250%0.522%0.216SC..THydrogen-bonded Turntrans-70.5-16.6-174.928.4-35.9000113.9I434 D440 M471I434-P438 VanDerWaalsContact O-CA 3.31Å; I434-P438 WeakPolarHBondContact O-CA 3.43Å; P438-D440 VanDerWaalsContact C-N 3.32Å; P438-D440 PolarHBondContact O-N 3.24Å; P438-M471 WeakPolarHBondContact O-CE 3.34Å
439D88.6Confident94.9Very high120 Ų12041.9 Ų41.964%0.64221%0.206SC*.THydrogen-bonded Turntrans-80.2-8.3-177.1-66.4-24.1000114K437 P441K437-D439 PolarHBondContact O-N 3.47Å; D439-P441 VanDerWaalsContact O-CD 3.31Å; D439-P441 WeakPolarHBondContact O-CD 3.47Å
440D91.6Very high94.9Very high26 Ų2641.6 Ų41.614%0.13920%0.204CC..  trans-96.6107.4-174.4-163.3-33.7000111.5K437 P438 T442 I443 P444K437-D440 HydrophobicContact CD-CB 4Å; K437-D440 HydrophobicContact CG-CB 4.21Å; K437-D440 IonicContact NZ-OD2 2.66Å; K437-D440 PolarHBondContact NZ-OD2 3.03Å; K437-D440 PolarHBondContact O-N 3.28Å; P438-D440 VanDerWaalsContact C-N 3.32Å; P438-D440 PolarHBondContact O-N 3.24Å; D440-T442 PolarHBondContact O-N 3.36Å; D440-T442 WeakPolarHBondContact OD1-CB 3.25Å; D440-T442 PolarHBondContact OD1-N 2.95Å; D440-T442 VanDerWaalsContact OD1-N 3.07Å; D440-T442 PolarHBondContact OD1-OG1 2.94Å; D440-I443 HydrophobicContact CB-CD1 3.76Å; D440-I443 HydrophobicContact CB-CG1 4.02Å; D440-P444 WeakPolarHBondContact O-CD 3.47Å
441P93.4Very high94.9Very high11 Ų1141.6 Ų41.67%0.07120%0.204CC..THydrogen-bonded Turntrans-70.9-16.8-177.528.9-35.3000113.2D439 I443 P444 L445 V468 M471 A475 F478D439-P441 VanDerWaalsContact O-CD 3.31Å; D439-P441 WeakPolarHBondContact O-CD 3.47Å; P441-I443 PolarHBondContact O-N 3.31Å; P441-P444 WeakPolarHBondContact O-CD 3.47Å; P441-P444 WeakPolarHBondContact O-CG 3.33Å; P441-L445 VanDerWaalsContact O-CG 3.3Å; P441-L445 WeakPolarHBondContact O-CG 3.46Å; P441-L445 PolarHBondContact O-N 2.89Å; P441-V468 HydrophobicContact CB-CG1 4.26Å; P441-M471 VanDerWaalsContact CA-SD 3.58Å; P441-M471 HydrophobicContact CB-SD 3.69Å; P441-A475 HydrophobicContact CB-CB 4.16Å; P441-A475 HydrophobicContact CG-CB 4.06Å; P441-F478 HydrophobicContact CB-CB 3.78Å; P441-F478 HydrophobicContact CB-CD1 4.36Å; P441-F478 HydrophobicContact CB-CD2 4.4Å; P441-F478 HydrophobicContact CB-CG 3.94Å; P441-F478 HydrophobicContact CG-CB 3.83Å; P441-F478 HydrophobicContact CG-CD1 4.08Å; P441-F478 HydrophobicContact CG-CD2 3.51Å; P441-F478 HydrophobicContact CG-CE2 4.05Å; P441-F478 HydrophobicContact CG-CG 3.53Å
442T94.3Very high94.8Very high49 Ų4938 Ų3830%0.30119%0.188SC..Hα-helixtrans-66.5-39.9-177.4-41.90000111.3D440 L445 L446D440-T442 PolarHBondContact O-N 3.36Å; D440-T442 WeakPolarHBondContact OD1-CB 3.25Å; D440-T442 PolarHBondContact OD1-N 2.95Å; D440-T442 VanDerWaalsContact OD1-N 3.07Å; D440-T442 PolarHBondContact OD1-OG1 2.94Å; T442-L445 PolarHBondContact O-N 3.07Å; T442-L446 HydrophobicContact CG2-CD1 4.29Å; T442-L446 HydrophobicContact CG2-CG 4.39Å; T442-L446 WeakPolarHBondContact O-CB 3.43Å; T442-L446 VanDerWaalsContact O-CG 3.3Å; T442-L446 WeakPolarHBondContact O-CG 3.26Å; T442-L446 PolarHBondContact O-N 3.47Å
443I95.8Very high94.6Very high0 Ų036.2 Ų36.20%019%0.189CC..Hα-helixtrans-63.4-52.5-174.8-46.4171.6000111.8F407 Y411 L430 C433 I434 K437 D440 P441 L445 L446 A447F407-I443 HydrophobicContact CE2-CD1 3.58Å; F407-I443 HydrophobicContact CZ-CD1 3.81Å; Y411-I443 HydrophobicContact CE2-CG1 4.08Å; L430-I443 HydrophobicContact CB-CG2 4.25Å; L430-I443 HydrophobicContact CD2-CG2 3.62Å; C433-I443 HydrophobicContact CB-CD1 4.18Å; C433-I443 HydrophobicContact CB-CG2 3.67Å; I434-I443 HydrophobicContact CD1-CG2 4.44Å; I434-I443 HydrophobicContact CG1-CB 4.08Å; I434-I443 HydrophobicContact CG1-CG2 3.68Å; K437-I443 HydrophobicContact CB-CD1 4.42Å; D440-I443 HydrophobicContact CB-CD1 3.76Å; D440-I443 HydrophobicContact CB-CG1 4.02Å; P441-I443 PolarHBondContact O-N 3.31Å; I443-L445 PolarHBondContact O-N 3.5Å; I443-L446 PolarHBondContact O-N 3.29Å; I443-A447 PolarHBondContact O-N 3.36Å; I443-A447 VanDerWaalsContact O-N 3.11Å
444P96.1Very high94.1Very high1 Ų140.9 Ų40.91%0.00622%0.22CC..Hα-helixtrans-65.8-34.1174.124-31.3000112.6I434 D440 P441 L446 A447 V448 F464 M467 V468 M471I434-P444 HydrophobicContact CD1-CB 3.93Å; I434-P444 HydrophobicContact CG1-CB 4.48Å; D440-P444 WeakPolarHBondContact O-CD 3.47Å; P441-P444 WeakPolarHBondContact O-CD 3.47Å; P441-P444 WeakPolarHBondContact O-CG 3.33Å; P444-L446 PolarHBondContact O-N 3.44Å; P444-A447 CarbonylContact O-C 3.56Å; P444-A447 WeakPolarHBondContact O-CA 3.47Å; P444-A447 WeakPolarHBondContact O-CB 3.23Å; P444-A447 PolarHBondContact O-N 3.3Å; P444-A447 VanDerWaalsContact O-N 3.1Å; P444-V448 WeakPolarHBondContact O-CG2 3.39Å; P444-V448 PolarHBondContact O-N 2.97Å; P444-F464 HydrophobicContact CB-CB 4.24Å; P444-F464 HydrophobicContact CB-CD1 4.25Å; P444-M467 HydrophobicContact CB-SD 4.34Å; P444-V468 HydrophobicContact CB-CG2 3.9Å; P444-V468 HydrophobicContact CG-CG2 3.62Å; P444-M471 HydrophobicContact CG-CE 3.72Å
445L95.5Very high94Very high22 Ų2241.8 Ų41.812%0.11522%0.224CC..Hα-helixtrans-61.3-42.7174.7-76.9172.5000112.5P441 T442 I443 A447 V448 K449 V468 F478 K481 A485P441-L445 VanDerWaalsContact O-CG 3.3Å; P441-L445 WeakPolarHBondContact O-CG 3.46Å; P441-L445 PolarHBondContact O-N 2.89Å; T442-L445 PolarHBondContact O-N 3.07Å; I443-L445 PolarHBondContact O-N 3.5Å; L445-A447 VanDerWaalsContact C-N 3.28Å; L445-A447 PolarHBondContact O-N 3.37Å; L445-V448 PolarHBondContact O-N 3.24Å; L445-K449 PolarHBondContact O-N 3.13Å; L445-V468 HydrophobicContact CD1-CG1 4.41Å; L445-V468 HydrophobicContact CD2-CG1 4.25Å; L445-V468 HydrophobicContact CD2-CG2 4.01Å; L445-V468 HydrophobicContact CG-CG1 4.22Å; L445-V468 HydrophobicContact CG-CG2 3.81Å; L445-F478 HydrophobicContact CD1-CD1 3.69Å; L445-F478 HydrophobicContact CD1-CE1 4.45Å; L445-K481 HydrophobicContact CD1-CB 4.09Å; L445-K481 HydrophobicContact CD1-CD 4.48Å; L445-K481 HydrophobicContact CD2-CB 4.32Å; L445-A485 HydrophobicContact CD2-CB 4.21Å
446L96.6Very high94Very high35 Ų3539.7 Ų39.718%0.18322%0.22CC..Hα-helixtrans-60.4-38.2172.5-75.3177.5000111.7Y411 L415 M418 L430 T442 I443 P444 K449 L450Y411-L446 HydrophobicContact CE2-CD1 4.44Å; L415-L446 HydrophobicContact CD2-CD1 3.82Å; M418-L446 HydrophobicContact CE-CB 3.64Å; M418-L446 HydrophobicContact CE-CD1 4.39Å; M418-L446 HydrophobicContact CE-CD2 4.05Å; M418-L446 HydrophobicContact CE-CG 4.23Å; M418-L446 HydrophobicContact SD-CD2 3.95Å; L430-L446 HydrophobicContact CD1-CB 4.23Å; T442-L446 HydrophobicContact CG2-CD1 4.29Å; T442-L446 HydrophobicContact CG2-CG 4.39Å; T442-L446 WeakPolarHBondContact O-CB 3.43Å; T442-L446 VanDerWaalsContact O-CG 3.3Å; T442-L446 WeakPolarHBondContact O-CG 3.26Å; T442-L446 PolarHBondContact O-N 3.47Å; I443-L446 PolarHBondContact O-N 3.29Å; P444-L446 PolarHBondContact O-N 3.44Å; L446-K449 PolarHBondContact O-N 3.48Å; L446-L450 PolarHBondContact O-N 3.05Å
447A97.1Very high94.1Very high0 Ų042.6 Ų42.60%023%0.228CC..Hα-helixtrans-66-41.617400000111.8L430 I443 P444 L445 K449 L450 C451 F464L430-A447 HydrophobicContact CB-CB 4.39Å; L430-A447 HydrophobicContact CD1-CB 4.01Å; I443-A447 PolarHBondContact O-N 3.36Å; I443-A447 VanDerWaalsContact O-N 3.11Å; P444-A447 CarbonylContact O-C 3.56Å; P444-A447 WeakPolarHBondContact O-CA 3.47Å; P444-A447 WeakPolarHBondContact O-CB 3.23Å; P444-A447 PolarHBondContact O-N 3.3Å; P444-A447 VanDerWaalsContact O-N 3.1Å; L445-A447 VanDerWaalsContact C-N 3.28Å; L445-A447 PolarHBondContact O-N 3.37Å; A447-K449 PolarHBondContact O-N 3.36Å; A447-L450 PolarHBondContact O-N 3.4Å; A447-C451 WeakPolarHBondContact O-CB 3.38Å; A447-C451 PolarHBondContact O-N 3.28Å; A447-C451 PolarHBondContact O-SG 3.36Å; A447-F464 HydrophobicContact CB-CD1 4.24Å; A447-F464 HydrophobicContact CB-CD2 3.71Å; A447-F464 HydrophobicContact CB-CE1 4.25Å; A447-F464 HydrophobicContact CB-CE2 3.72Å; A447-F464 HydrophobicContact CB-CG 3.96Å; A447-F464 HydrophobicContact CB-CZ 3.96Å
448V97.3Very high94.3Very high0 Ų039 Ų390%021%0.213CC..Hα-helixtrans-58.7-47.9174.4-174.10000110.4P444 L445 L450 C451 I452 F464 A465 A485 V489 L854P444-V448 WeakPolarHBondContact O-CG2 3.39Å; P444-V448 PolarHBondContact O-N 2.97Å; L445-V448 PolarHBondContact O-N 3.24Å; V448-L450 VanDerWaalsContact C-N 3.28Å; V448-L450 PolarHBondContact O-N 3.24Å; V448-C451 WeakPolarHBondContact O-CA 3.18Å; V448-C451 WeakPolarHBondContact O-CB 3.29Å; V448-C451 PolarHBondContact O-N 3.32Å; V448-I452 HydrophobicContact CG1-CG2 3.92Å; V448-I452 WeakPolarHBondContact O-CG1 3.39Å; V448-I452 PolarHBondContact O-N 2.84Å; V448-F464 HydrophobicContact CG2-CB 3.51Å; V448-A465 HydrophobicContact CG1-CB 4.39Å; V448-A465 HydrophobicContact CG2-CB 3.79Å; V448-A485 HydrophobicContact CG1-CB 4.13Å; V448-V489 HydrophobicContact CG1-CG2 4.23Å; V448-L854 HydrophobicContact CB-CD1 3.76Å; V448-L854 HydrophobicContact CG1-CD1 3.46Å; V448-L854 VanDerWaalsContact CG1-CD1 3.46Å
449K96.3Very high94.6Very high94 Ų9440.3 Ų40.341%0.40922%0.216SC..Hα-helixtrans-52.9-44.9178.9177.4176.5-179.4123.20112.3L445 L446 A447 G453 L854L445-K449 PolarHBondContact O-N 3.13Å; L446-K449 PolarHBondContact O-N 3.48Å; A447-K449 PolarHBondContact O-N 3.36Å; K449-G453 PolarHBondContact O-N 2.75Å; K449-G453 VanDerWaalsContact O-N 3.08Å; K449-L854 HydrophobicContact CB-CB 3.98Å; K449-L854 WeakPolarHBondContact CD-O 3.36Å; K449-L854 VanDerWaalsContact CE-O 3.23Å; K449-L854 WeakPolarHBondContact CE-O 2.93Å; K449-L854 HydrophobicContact CG-CB 4.25Å; K449-L854 WeakPolarHBondContact CG-O 3.37Å; K449-L854 PolarHBondContact NZ-O 3.2Å
450L96.2Very high95Very high11 Ų1136.8 Ų36.86%0.05820%0.195CC..Hα-helixtrans-68.5-39.4176.2-72.5-176.8000113M418 A426 V427 L430 L446 A447 V448 L455M418-L450 HydrophobicContact CE-CD1 3.6Å; M418-L450 HydrophobicContact CE-CG 3.86Å; M418-L450 HydrophobicContact CG-CD1 4.21Å; M418-L450 HydrophobicContact CG-CD2 4Å; M418-L450 HydrophobicContact CG-CG 4.34Å; A426-L450 HydrophobicContact CB-CD1 3.56Å; V427-L450 HydrophobicContact CG2-CB 3.72Å; V427-L450 HydrophobicContact CG2-CD1 3.91Å; L430-L450 HydrophobicContact CD1-CD1 4.24Å; L446-L450 PolarHBondContact O-N 3.05Å; A447-L450 PolarHBondContact O-N 3.4Å; V448-L450 VanDerWaalsContact C-N 3.28Å; V448-L450 PolarHBondContact O-N 3.24Å; L450-L455 HydrophobicContact CB-CD1 4.49Å; L450-L455 WeakPolarHBondContact O-CB 3.38Å; L450-L455 PolarHBondContact O-N 3.42Å
451C96.7Very high95.2Very high0 Ų035.5 Ų35.50%019%0.189CC..Hα-helixtrans-66-44.2179.1-75.10000112.4A447 V448 H456 W457A447-C451 WeakPolarHBondContact O-CB 3.38Å; A447-C451 PolarHBondContact O-N 3.28Å; A447-C451 PolarHBondContact O-SG 3.36Å; V448-C451 WeakPolarHBondContact O-CA 3.18Å; V448-C451 WeakPolarHBondContact O-CB 3.29Å; V448-C451 PolarHBondContact O-N 3.32Å; C451-H456 CarbonylContact O-C 3.59Å; C451-H456 VanDerWaalsContact O-CA 3.26Å; C451-H456 WeakPolarHBondContact O-CA 3.34Å; C451-H456 PolarHBondContact O-N 3.22Å; C451-W457 HydrophobicContact CB-CB 4.25Å; C451-W457 PolarHBondContact O-N 2.95Å
452I94.5Very high95.4Very high8 Ų836.6 Ų36.64%0.04119%0.193CC..Hα-helixtrans-82.5-21-17969.4173.8000113.6V448 L458 L488 V489 L492 L854V448-I452 HydrophobicContact CG1-CG2 3.92Å; V448-I452 WeakPolarHBondContact O-CG1 3.39Å; V448-I452 PolarHBondContact O-N 2.84Å; I452-L458 HydrophobicContact CG2-CD2 4.38Å; I452-L488 HydrophobicContact CD1-CB 4.12Å; I452-L488 HydrophobicContact CD1-CD1 4.13Å; I452-V489 HydrophobicContact CG2-CG2 3.49Å; I452-V489 VanDerWaalsContact CG2-CG2 3.49Å; I452-L492 HydrophobicContact CB-CD1 3.8Å; I452-L492 HydrophobicContact CG2-CD1 4.29Å; I452-L854 HydrophobicContact CD1-CB 4.04Å; I452-L854 HydrophobicContact CD1-CD1 3.76Å; I452-L854 HydrophobicContact CD1-CG 3.69Å
453G91.3Very high95.6Very high33 Ų3340.1 Ų40.134%0.3420%0.204SC..THydrogen-bonded Turntrans-83.8-113.817800000111.8K449 L455K449-G453 PolarHBondContact O-N 2.75Å; K449-G453 VanDerWaalsContact O-N 3.08Å; G453-L455 VanDerWaalsContact C-N 3.32Å; G453-L455 PolarHBondContact O-N 3.05Å
454P86Confident95.6Very high99 Ų9940.6 Ų40.664%0.64321%0.206SC*.THydrogen-bonded Turntrans-68.6-23.7-168.927.3-35.5000114.9S423S423-P454 WeakPolarHBondContact OG-CG 3.47Å
455L92.9Very high95.6Very high38 Ų3840.5 Ų40.520%0.19921%0.206CC..THydrogen-bonded Turntrans-86.6-26.1-175.6-65.2176.6000113.9A424 V427 L450 G453 W457A424-L455 HydrophobicContact CB-CD2 3.9Å; V427-L455 HydrophobicContact CG2-CD1 3.79Å; L450-L455 HydrophobicContact CB-CD1 4.49Å; L450-L455 WeakPolarHBondContact O-CB 3.38Å; L450-L455 PolarHBondContact O-N 3.42Å; G453-L455 VanDerWaalsContact C-N 3.32Å; G453-L455 PolarHBondContact O-N 3.05Å; L455-W457 HydrophobicContact CB-CD2 4.04Å; L455-W457 HydrophobicContact CB-CG 3.98Å; L455-W457 HydrophobicContact CD1-CD2 4.11Å; L455-W457 HydrophobicContact CD1-CE3 3.88Å; L455-W457 HydrophobicContact CD1-CH2 4.28Å; L455-W457 HydrophobicContact CD1-CZ2 4.5Å; L455-W457 HydrophobicContact CD1-CZ3 3.96Å; L455-W457 HydrophobicContact CD2-CZ2 4.35Å; L455-W457 PolarHBondContact O-N 2.9Å
456H95.1Very high95.6Very high84 Ų8443.3 Ų43.339%0.38922%0.217SC..  trans53.833.9-174.3-153.261.4000114.4C451 L458 D496C451-H456 CarbonylContact O-C 3.59Å; C451-H456 VanDerWaalsContact O-CA 3.26Å; C451-H456 WeakPolarHBondContact O-CA 3.34Å; C451-H456 PolarHBondContact O-N 3.22Å; H456-L458 VanDerWaalsContact C-N 3.32Å; H456-L458 PolarHBondContact O-N 3.42Å; H456-L458 VanDerWaalsContact O-N 3.15Å; H456-D496 IonicContact CD2-OD2 3.86Å; H456-D496 IonicContact CE1-OD1 2.85Å; H456-D496 IonicContact CE1-OD2 3.85Å; H456-D496 PolarHBondContact CE1-OD2 3.38Å; H456-D496 IonicContact NE2-OD1 2.84Å; H456-D496 PolarHBondContact NE2-OD1 3.41Å; H456-D496 IonicContact NE2-OD2 2.65Å; H456-D496 PolarHBondContact NE2-OD2 3.47Å
457W97.2Very high95.5Very high101 Ų10145.3 Ų45.338%0.38323%0.226SC..  trans-87.266176.9-66.5-4.6000111.1A424 V427 C451 L455 D459 E460 G461A424-W457 HydrophobicContact CB-CH2 3.79Å; A424-W457 HydrophobicContact CB-CZ2 4.21Å; V427-W457 HydrophobicContact CB-CZ3 4.36Å; V427-W457 HydrophobicContact CG1-CE3 4.49Å; V427-W457 HydrophobicContact CG1-CZ3 4.22Å; C451-W457 HydrophobicContact CB-CB 4.25Å; C451-W457 PolarHBondContact O-N 2.95Å; L455-W457 HydrophobicContact CB-CD2 4.04Å; L455-W457 HydrophobicContact CB-CG 3.98Å; L455-W457 HydrophobicContact CD1-CD2 4.11Å; L455-W457 HydrophobicContact CD1-CE3 3.88Å; L455-W457 HydrophobicContact CD1-CH2 4.28Å; L455-W457 HydrophobicContact CD1-CZ2 4.5Å; L455-W457 HydrophobicContact CD1-CZ3 3.96Å; L455-W457 HydrophobicContact CD2-CZ2 4.35Å; L455-W457 PolarHBondContact O-N 2.9Å; W457-D459 VanDerWaalsContact C-N 3.31Å; W457-D459 PolarHBondContact O-N 3.12Å; W457-E460 HydrophobicContact CB-CB 4.29Å; W457-E460 PolarHBondContact O-N 3.43Å; W457-G461 PolarHBondContact O-N 2.89Å
458L97.3Very high95.4Very high11 Ų1145.3 Ų45.36%0.05823%0.226CC..Hα-helixtrans-60.7-34.8-170.8-56.4-175.9000113.8I452 H456 G461 E462 V489 L492 K493 D496I452-L458 HydrophobicContact CG2-CD2 4.38Å; H456-L458 VanDerWaalsContact C-N 3.32Å; H456-L458 PolarHBondContact O-N 3.42Å; H456-L458 VanDerWaalsContact O-N 3.15Å; L458-G461 PolarHBondContact O-N 2.89Å; L458-E462 PolarHBondContact O-N 3.17Å; L458-V489 HydrophobicContact CB-CG1 4.43Å; L458-V489 VanDerWaalsContact O-CG1 3.29Å; L458-V489 WeakPolarHBondContact O-CG1 3.17Å; L458-L492 HydrophobicContact CD1-CB 3.84Å; L458-L492 HydrophobicContact CD2-CB 3.8Å; L458-L492 HydrophobicContact CD2-CD1 3.85Å; L458-L492 HydrophobicContact CD2-CG 4.46Å; L458-K493 HydrophobicContact CB-CG 3.91Å; L458-K493 HydrophobicContact CD1-CB 4.45Å; L458-K493 HydrophobicContact CD1-CG 3.72Å; L458-K493 HydrophobicContact CG-CG 4.47Å; L458-D496 WeakPolarHBondContact CD1-OD2 3.29Å
459D97.2Very high95.2Very high104 Ų10446.5 Ų46.556%0.55623%0.232SC*.Hα-helixtrans-67.9-39.3177.5-68.1-38.5000113W457 E462 K463 K493W457-D459 VanDerWaalsContact C-N 3.31Å; W457-D459 PolarHBondContact O-N 3.12Å; D459-E462 PolarHBondContact O-N 3.45Å; D459-K463 WeakPolarHBondContact O-CG 3.45Å; D459-K463 PolarHBondContact O-N 3.41Å; D459-K493 VanDerWaalsContact OD1-CE 3.3Å; D459-K493 WeakPolarHBondContact OD1-CE 3.45Å; D459-K493 IonicContact OD1-NZ 2.93Å; D459-K493 PolarHBondContact OD1-NZ 2.96Å
460E96.5Very high94.9Very high45 Ų4548.3 Ų48.321%0.2125%0.246CC..Hα-helixtrans-71.5-39174.8-69.5-68.5119.300110.7K431 W457 E462 K463 F464K431-E460 WeakPolarHBondContact CE-OE2 3.37Å; K431-E460 IonicContact NZ-OE2 3.65Å; K431-E460 PolarHBondContact NZ-OE2 3.2Å; W457-E460 HydrophobicContact CB-CB 4.29Å; W457-E460 PolarHBondContact O-N 3.43Å; E460-E462 VanDerWaalsContact C-N 3.29Å; E460-E462 PolarHBondContact O-N 2.98Å; E460-K463 PolarHBondContact O-N 3.47Å; E460-K463 VanDerWaalsContact O-N 3.16Å; E460-K463 IonicContact OE1-NZ 3.29Å; E460-K463 PolarHBondContact OE1-NZ 3.46Å; E460-F464 HydrophobicContact CB-CE2 4.42Å; E460-F464 WeakPolarHBondContact O-CD2 3.35Å; E460-F464 PolarHBondContact O-N 2.95Å
461G96.5Very high94.6Very high0 Ų049.3 Ų49.30%025%0.251CS..Hα-helixtrans-56.9-41.4172.300000112.4W457 L458 K463 F464 A465W457-G461 PolarHBondContact O-N 2.89Å; L458-G461 PolarHBondContact O-N 2.89Å; G461-K463 PolarHBondContact O-N 3.45Å; G461-F464 PolarHBondContact O-N 3.27Å; G461-A465 VanDerWaalsContact O-CB 3.25Å; G461-A465 WeakPolarHBondContact O-CB 3.5Å; G461-A465 PolarHBondContact O-N 3.49Å
462E97.6Very high93.8Very high33 Ų3352 Ų5215%0.15428%0.279CS..Hα-helixtrans-60.3-45175.2-167.8-175.8143.800112.1L458 D459 E460 A465 K466 V489 Y490 K493L458-E462 PolarHBondContact O-N 3.17Å; D459-E462 PolarHBondContact O-N 3.45Å; E460-E462 VanDerWaalsContact C-N 3.29Å; E460-E462 PolarHBondContact O-N 2.98Å; E462-A465 PolarHBondContact O-N 3.29Å; E462-K466 HydrophobicContact CG-CD 4.16Å; E462-K466 WeakPolarHBondContact O-CB 3.41Å; E462-K466 WeakPolarHBondContact O-CG 3.15Å; E462-K466 PolarHBondContact O-N 3.29Å; E462-K466 VanDerWaalsContact OE1-CE 3.28Å; E462-K466 WeakPolarHBondContact OE1-CE 3.43Å; E462-K466 IonicContact OE1-NZ 2.9Å; E462-K466 PolarHBondContact OE1-NZ 3.49Å; E462-V489 HydrophobicContact CB-CG1 3.92Å; E462-Y490 PolarHBondContact OE1-OH 3.07Å; E462-K493 IonicContact OE2-NZ 2.84Å; E462-K493 PolarHBondContact OE2-NZ 3.1Å
463K97.3Very high92.8Very high124 Ų12460.7 Ų60.754%0.53932%0.32SS..Hα-helixtrans-62.2-47.1-179.8-67.3171.8-168.4170.10111.4D459 E460 G461 K466 M467D459-K463 WeakPolarHBondContact O-CG 3.45Å; D459-K463 PolarHBondContact O-N 3.41Å; E460-K463 PolarHBondContact O-N 3.47Å; E460-K463 VanDerWaalsContact O-N 3.16Å; E460-K463 IonicContact OE1-NZ 3.29Å; E460-K463 PolarHBondContact OE1-NZ 3.46Å; G461-K463 PolarHBondContact O-N 3.45Å; K463-K466 PolarHBondContact O-N 2.92Å; K463-M467 WeakPolarHBondContact O-CB 3.42Å; K463-M467 PolarHBondContact O-N 3.17Å
464F96.8Very high91.6Very high9 Ų968.4 Ų68.44%0.03934%0.344CS..Hα-helixtrans-66.3-40178.2-68.8-55.8000112.4V427 K431 I434 P444 A447 V448 E460 G461 M467 V468V427-F464 HydrophobicContact CG1-CE2 4.02Å; V427-F464 HydrophobicContact CG1-CZ 4.27Å; K431-F464 HydrophobicContact CD-CZ 4.17Å; K431-F464 HydrophobicContact CG-CE1 4.02Å; K431-F464 HydrophobicContact CG-CZ 3.64Å; I434-F464 HydrophobicContact CD1-CD1 3.82Å; I434-F464 HydrophobicContact CD1-CE1 3.55Å; P444-F464 HydrophobicContact CB-CB 4.24Å; P444-F464 HydrophobicContact CB-CD1 4.25Å; A447-F464 HydrophobicContact CB-CD1 4.24Å; A447-F464 HydrophobicContact CB-CD2 3.71Å; A447-F464 HydrophobicContact CB-CE1 4.25Å; A447-F464 HydrophobicContact CB-CE2 3.72Å; A447-F464 HydrophobicContact CB-CG 3.96Å; A447-F464 HydrophobicContact CB-CZ 3.96Å; V448-F464 HydrophobicContact CG2-CB 3.51Å; E460-F464 HydrophobicContact CB-CE2 4.42Å; E460-F464 WeakPolarHBondContact O-CD2 3.35Å; E460-F464 PolarHBondContact O-N 2.95Å; G461-F464 PolarHBondContact O-N 3.27Å; F464-M467 WeakPolarHBondContact O-CB 3.36Å; F464-M467 PolarHBondContact O-N 2.62Å; F464-V468 WeakPolarHBondContact O-CG2 3.38Å; F464-V468 PolarHBondContact O-N 3Å; F464-V468 VanDerWaalsContact O-N 3.17Å
465A96.1Very high91Very high0 Ų064 Ų640%032%0.315CS..Hα-helixtrans-67.1-39.8179.100000111.7V448 G461 E462 V468 I469 A485 V486V448-A465 HydrophobicContact CG1-CB 4.39Å; V448-A465 HydrophobicContact CG2-CB 3.79Å; G461-A465 VanDerWaalsContact O-CB 3.25Å; G461-A465 WeakPolarHBondContact O-CB 3.5Å; G461-A465 PolarHBondContact O-N 3.49Å; E462-A465 PolarHBondContact O-N 3.29Å; A465-V468 PolarHBondContact O-N 3.41Å; A465-I469 WeakPolarHBondContact O-CG1 3.43Å; A465-I469 PolarHBondContact O-N 2.75Å; A465-A485 HydrophobicContact CB-CB 3.82Å; A465-V486 HydrophobicContact CB-CB 4.35Å; A465-V486 HydrophobicContact CB-CG2 3.39Å
466K95.6Very high90.3Very high81 Ų8165.3 Ų65.335%0.35233%0.332SS..Hα-helixtrans-63.9-41.1171.7-75.6177.3172.8174.70112.3E462 K463 V468 I469 D470 V486E462-K466 HydrophobicContact CG-CD 4.16Å; E462-K466 WeakPolarHBondContact O-CB 3.41Å; E462-K466 WeakPolarHBondContact O-CG 3.15Å; E462-K466 PolarHBondContact O-N 3.29Å; E462-K466 VanDerWaalsContact OE1-CE 3.28Å; E462-K466 WeakPolarHBondContact OE1-CE 3.43Å; E462-K466 IonicContact OE1-NZ 2.9Å; E462-K466 PolarHBondContact OE1-NZ 3.49Å; K463-K466 PolarHBondContact O-N 2.92Å; K466-V468 PolarHBondContact O-N 3.24Å; K466-I469 WeakPolarHBondContact O-CB 3.43Å; K466-I469 PolarHBondContact O-N 3.1Å; K466-D470 PolarHBondContact O-N 2.98Å; K466-V486 HydrophobicContact CG-CG2 4.26Å
467M94.5Very high89.5Confident76 Ų7669.4 Ų69.437%0.37435%0.351SS..Hα-helixtrans-54-42.9175.2-175.1-177.6-66.500111.6I434 P444 K463 F464 I469 D470 M471I434-M467 HydrophobicContact CD1-SD 4.48Å; I434-M467 HydrophobicContact CG2-CE 4.39Å; I434-M467 HydrophobicContact CG2-SD 3.66Å; P444-M467 HydrophobicContact CB-SD 4.34Å; K463-M467 WeakPolarHBondContact O-CB 3.42Å; K463-M467 PolarHBondContact O-N 3.17Å; F464-M467 WeakPolarHBondContact O-CB 3.36Å; F464-M467 PolarHBondContact O-N 2.62Å; M467-I469 PolarHBondContact O-N 3.06Å; M467-D470 PolarHBondContact O-N 3.39Å; M467-M471 HydrophobicContact CG-CE 4.28Å; M467-M471 WeakPolarHBondContact O-CG 3.31Å; M467-M471 PolarHBondContact O-N 2.98Å
468V93.8Very high89.1Confident1 Ų167.5 Ų67.51%0.00635%0.346CS..Hα-helixtrans-62.7-39.7176177.70000112.2P441 P444 L445 F464 A465 K466 D470 M471 F478P441-V468 HydrophobicContact CB-CG1 4.26Å; P444-V468 HydrophobicContact CB-CG2 3.9Å; P444-V468 HydrophobicContact CG-CG2 3.62Å; L445-V468 HydrophobicContact CD1-CG1 4.41Å; L445-V468 HydrophobicContact CD2-CG1 4.25Å; L445-V468 HydrophobicContact CD2-CG2 4.01Å; L445-V468 HydrophobicContact CG-CG1 4.22Å; L445-V468 HydrophobicContact CG-CG2 3.81Å; F464-V468 WeakPolarHBondContact O-CG2 3.38Å; F464-V468 PolarHBondContact O-N 3Å; F464-V468 VanDerWaalsContact O-N 3.17Å; A465-V468 PolarHBondContact O-N 3.41Å; K466-V468 PolarHBondContact O-N 3.24Å; V468-D470 VanDerWaalsContact C-N 3.32Å; V468-M471 PolarHBondContact O-N 3.39Å; V468-F478 HydrophobicContact CG1-CB 4.48Å
469I93.1Very high88.9Confident24 Ų2470.9 Ų70.912%0.12336%0.36CS..Hα-helixtrans-67.7-36-179.9-65.1169000111.4A465 K466 M467 M471 K479 V486A465-I469 WeakPolarHBondContact O-CG1 3.43Å; A465-I469 PolarHBondContact O-N 2.75Å; K466-I469 WeakPolarHBondContact O-CB 3.43Å; K466-I469 PolarHBondContact O-N 3.1Å; M467-I469 PolarHBondContact O-N 3.06Å; I469-M471 VanDerWaalsContact C-N 3.28Å; I469-K479 WeakPolarHBondContact O-CE 3.08Å; I469-V486 HydrophobicContact CD1-CB 4.25Å; I469-V486 HydrophobicContact CD1-CG2 3.51Å
470D91.6Very high88.7Confident132 Ų13266.2 Ų66.271%0.70634%0.336SS*.THydrogen-bonded Turntrans-82.2-4.7-177.2-63.2-23.7000112.8K466 M467 V468K466-D470 PolarHBondContact O-N 2.98Å; M467-D470 PolarHBondContact O-N 3.39Å; V468-D470 VanDerWaalsContact C-N 3.32Å
471M89.4Confident88.6Confident32 Ų3268.8 Ų68.816%0.15835%0.346CS..SBendtrans-66150.1174.2-71.1-175.9177.600112P438 P441 P444 M467 V468 I469 A475P438-M471 WeakPolarHBondContact O-CE 3.34Å; P441-M471 VanDerWaalsContact CA-SD 3.58Å; P441-M471 HydrophobicContact CB-SD 3.69Å; P444-M471 HydrophobicContact CG-CE 3.72Å; M467-M471 HydrophobicContact CG-CE 4.28Å; M467-M471 WeakPolarHBondContact O-CG 3.31Å; M467-M471 PolarHBondContact O-N 2.98Å; V468-M471 PolarHBondContact O-N 3.39Å; I469-M471 VanDerWaalsContact C-N 3.28Å; M471-A475 HydrophobicContact CB-CB 3.74Å; M471-A475 HydrophobicContact SD-CB 4.39Å
472G79.4Confident88.5Confident58 Ų5868.8 Ų68.860%0.59835%0.346SS*.  trans-66.8-177-177.900000114.6K474 A475G472-K474 PolarHBondContact O-N 3.36Å; G472-A475 PolarHBondContact O-N 2.9Å
473E74.6Confident88.5Confident189 Ų18968.2 Ų68.288%0.88334%0.344SS*.G310 helixtrans-56.1-26.2-171.3-64.4-174.5164.500115A475 A476E473-A475 PolarHBondContact O-N 3.29Å; E473-A476 VanDerWaalsContact O-CB 3.27Å; E473-A476 WeakPolarHBondContact O-CB 3.36Å; E473-A476 PolarHBondContact O-N 2.98Å; E473-A476 VanDerWaalsContact O-N 3.1Å
474K65.9Low88.4Confident196 Ų19662.5 Ų62.585%0.85232%0.319SS*.G310 helixtrans-62.4-21.6176.8-65.6-177.1-177.5174.70113.6G472G472-K474 PolarHBondContact O-N 3.36Å
475A73.6Confident88.5Confident5 Ų562 Ų624%0.04132%0.317CS..G310 helixtrans-101.415.5178.300000112.9P441 M471 G472 E473 E477 F478 K479P441-A475 HydrophobicContact CB-CB 4.16Å; P441-A475 HydrophobicContact CG-CB 4.06Å; M471-A475 HydrophobicContact CB-CB 3.74Å; M471-A475 HydrophobicContact SD-CB 4.39Å; G472-A475 PolarHBondContact O-N 2.9Å; E473-A475 PolarHBondContact O-N 3.29Å; A475-E477 VanDerWaalsContact C-N 3.26Å; A475-E477 PolarHBondContact O-N 3.4Å; A475-F478 CarbonylContact O-C 3.21Å; A475-F478 WeakPolarHBondContact O-CA 3.33Å; A475-F478 PolarHBondContact O-N 3.4Å; A475-K479 PolarHBondContact O-N 3.47Å
476A76.7Confident88.5Confident66 Ų6662.5 Ų62.555%0.54532%0.32SS..Hα-helixtrans-54.2-40.1-17500000113.3E473 F478 K479E473-A476 VanDerWaalsContact O-CB 3.27Å; E473-A476 WeakPolarHBondContact O-CB 3.36Å; E473-A476 PolarHBondContact O-N 2.98Å; E473-A476 VanDerWaalsContact O-N 3.1Å; A476-F478 VanDerWaalsContact C-N 3.29Å; A476-F478 PolarHBondContact O-N 3.32Å; A476-K479 WeakPolarHBondContact O-CB 3.2Å; A476-K479 PolarHBondContact O-N 3.21Å
477E79.1Confident88.6Confident171 Ų17158.6 Ų58.680%0.79930%0.303SS*.Hα-helixtrans-65.9-30.7176.6-62.7-174.3172.200112.8A475A475-E477 VanDerWaalsContact C-N 3.26Å; A475-E477 PolarHBondContact O-N 3.4Å
478F89.3Confident88.8Confident61 Ų6155 Ų5527%0.26829%0.285SS..Hα-helixtrans-86.6-11.9178.7-70.5-90.5000113.1P441 L445 V468 A475 A476 A480 K481 G482P441-F478 HydrophobicContact CB-CB 3.78Å; P441-F478 HydrophobicContact CB-CD1 4.36Å; P441-F478 HydrophobicContact CB-CD2 4.4Å; P441-F478 HydrophobicContact CB-CG 3.94Å; P441-F478 HydrophobicContact CG-CB 3.83Å; P441-F478 HydrophobicContact CG-CD1 4.08Å; P441-F478 HydrophobicContact CG-CD2 3.51Å; P441-F478 HydrophobicContact CG-CE2 4.05Å; P441-F478 HydrophobicContact CG-CG 3.53Å; L445-F478 HydrophobicContact CD1-CD1 3.69Å; L445-F478 HydrophobicContact CD1-CE1 4.45Å; V468-F478 HydrophobicContact CG1-CB 4.48Å; A475-F478 CarbonylContact O-C 3.21Å; A475-F478 WeakPolarHBondContact O-CA 3.33Å; A475-F478 PolarHBondContact O-N 3.4Å; A476-F478 VanDerWaalsContact C-N 3.29Å; A476-F478 PolarHBondContact O-N 3.32Å; F478-A480 VanDerWaalsContact C-N 3.27Å; F478-A480 PolarHBondContact O-N 3.41Å; F478-K481 HydrophobicContact CD1-CD 4.23Å; F478-K481 CarbonylContact O-C 3.48Å; F478-K481 WeakPolarHBondContact O-CA 3.46Å; F478-K481 WeakPolarHBondContact O-CB 3.37Å; F478-K481 PolarHBondContact O-N 3.25Å; F478-G482 PolarHBondContact O-N 2.75Å
479K92.2Very high89Confident82 Ų8255 Ų5536%0.35729%0.285SS..Hα-helixtrans-61.4-37.8178.4-165.5167.8-171.9162.50111.8I469 A475 A476 G482 H483 M520I469-K479 WeakPolarHBondContact O-CE 3.08Å; A475-K479 PolarHBondContact O-N 3.47Å; A476-K479 WeakPolarHBondContact O-CB 3.2Å; A476-K479 PolarHBondContact O-N 3.21Å; K479-G482 PolarHBondContact O-N 2.92Å; K479-H483 PolarHBondContact O-CD2 3.38Å; K479-H483 VanDerWaalsContact O-CD2 3.32Å; K479-H483 PolarHBondContact O-N 3.24Å; K479-M520 HydrophobicContact CD-SD 4.45Å; K479-M520 HydrophobicContact CG-SD 4.17Å
480A93.3Very high89.2Confident6 Ų655.1 Ų55.15%0.0528%0.284CS..Hα-helixtrans-58-46.6171.600000111.6F478 G482 H483 L484 A517 M520F478-A480 VanDerWaalsContact C-N 3.27Å; F478-A480 PolarHBondContact O-N 3.41Å; A480-G482 PolarHBondContact O-N 3.35Å; A480-H483 PolarHBondContact O-N 3.43Å; A480-L484 PolarHBondContact O-N 3.07Å; A480-A517 WeakPolarHBondContact O-CB 3.43Å; A480-M520 HydrophobicContact CB-CB 4.06Å; A480-M520 HydrophobicContact CB-CE 4.45Å
481K94.4Very high89.5Confident99 Ų9949.1 Ų49.143%0.4325%0.252SS..Hα-helixtrans-64.9-35.6175.3-67.8-173.8175.7-178.50113L445 F478 L484 A485L445-K481 HydrophobicContact CD1-CB 4.09Å; L445-K481 HydrophobicContact CD1-CD 4.48Å; L445-K481 HydrophobicContact CD2-CB 4.32Å; F478-K481 HydrophobicContact CD1-CD 4.23Å; F478-K481 CarbonylContact O-C 3.48Å; F478-K481 WeakPolarHBondContact O-CA 3.46Å; F478-K481 WeakPolarHBondContact O-CB 3.37Å; F478-K481 PolarHBondContact O-N 3.25Å; K481-L484 PolarHBondContact O-N 3.41Å; K481-A485 VanDerWaalsContact O-CB 3.22Å; K481-A485 WeakPolarHBondContact O-CB 3.43Å; K481-A485 PolarHBondContact O-N 3.47Å
482G95.1Very high89.9Confident0 Ų048.4 Ų48.40%025%0.249CC..Hα-helixtrans-61.3-44.8172.100000112.1F478 K479 A480 A485 V486F478-G482 PolarHBondContact O-N 2.75Å; K479-G482 PolarHBondContact O-N 2.92Å; A480-G482 PolarHBondContact O-N 3.35Å; G482-A485 WeakPolarHBondContact O-CB 3.39Å; G482-A485 PolarHBondContact O-N 2.87Å; G482-V486 WeakPolarHBondContact O-CG2 3.47Å; G482-V486 PolarHBondContact O-N 3.17Å
483H96.4Very high90.7Very high20 Ų2046.3 Ų46.39%0.09322%0.224CC..Hα-helixtrans-66-39.9174.7-83.8-75.3000112.9K479 A480 V486 G487 R516 A517 M520K479-H483 PolarHBondContact O-CD2 3.38Å; K479-H483 VanDerWaalsContact O-CD2 3.32Å; K479-H483 PolarHBondContact O-N 3.24Å; A480-H483 PolarHBondContact O-N 3.43Å; H483-V486 PolarHBondContact O-N 3.41Å; H483-G487 PolarHBondContact O-N 3.36Å; H483-R516 HydrophobicContact CB-CB 4.5Å; H483-A517 HydrophobicContact CB-CB 4.01Å; H483-M520 HydrophobicContact CB-CE 3.84Å; H483-M520 WeakPolarHBondContact CD2-CE 3.22Å
484L96.6Very high91.7Very high4 Ų437.7 Ų37.72%0.02119%0.185CC..Hα-helixtrans-58.8-48172.3-177.768.9000111.1A480 K481 V486 G487 L488 F514 A517 L526 Y530 L854A480-L484 PolarHBondContact O-N 3.07Å; K481-L484 PolarHBondContact O-N 3.41Å; L484-V486 PolarHBondContact O-N 2.88Å; L484-G487 WeakPolarHBondContact O-CA 3.09Å; L484-G487 PolarHBondContact O-N 3.17Å; L484-G487 VanDerWaalsContact O-N 3.12Å; L484-L488 HydrophobicContact CG-CD1 4.46Å; L484-L488 WeakPolarHBondContact O-CG 3.44Å; L484-L488 PolarHBondContact O-N 3.36Å; L484-F514 HydrophobicContact CD1-CD1 3.75Å; L484-F514 HydrophobicContact CD1-CE1 3.76Å; L484-F514 WeakPolarHBondContact O-CE1 3.43Å; L484-A517 HydrophobicContact CB-CB 4.14Å; L484-L526 HydrophobicContact CD2-CB 4.15Å; L484-Y530 HydrophobicContact CD1-CD2 3.68Å; L484-Y530 HydrophobicContact CD1-CG 4.23Å; L484-Y530 HydrophobicContact CG-CD2 4.4Å; L484-L854 HydrophobicContact CD2-CD2 4.37Å
485A97.1Very high93Very high0 Ų032 Ų320%017%0.166CC..Hα-helixtrans-59.1-46.2177.800000112.4L445 V448 A465 K481 G482 G487 L488 V489 L854L445-A485 HydrophobicContact CD2-CB 4.21Å; V448-A485 HydrophobicContact CG1-CB 4.13Å; A465-A485 HydrophobicContact CB-CB 3.82Å; K481-A485 VanDerWaalsContact O-CB 3.22Å; K481-A485 WeakPolarHBondContact O-CB 3.43Å; K481-A485 PolarHBondContact O-N 3.47Å; G482-A485 WeakPolarHBondContact O-CB 3.39Å; G482-A485 PolarHBondContact O-N 2.87Å; A485-G487 VanDerWaalsContact C-N 3.32Å; A485-G487 PolarHBondContact O-N 2.9Å; A485-L488 PolarHBondContact O-N 3.33Å; A485-V489 WeakPolarHBondContact O-CG2 3.41Å; A485-V489 PolarHBondContact O-N 2.87Å; A485-L854 HydrophobicContact CB-CD1 3.65Å; A485-L854 HydrophobicContact CB-CD2 4.16Å; A485-L854 HydrophobicContact CB-CG 4.46Å
486V97.5Very high93.9Very high9 Ų936.1 Ų36.16%0.05519%0.187CC..Hα-helixtrans-61.9-40.5173.7169.10000111.4A465 K466 I469 G482 H483 L484 L488 V489 Y490 A513A465-V486 HydrophobicContact CB-CB 4.35Å; A465-V486 HydrophobicContact CB-CG2 3.39Å; K466-V486 HydrophobicContact CG-CG2 4.26Å; I469-V486 HydrophobicContact CD1-CB 4.25Å; I469-V486 HydrophobicContact CD1-CG2 3.51Å; G482-V486 WeakPolarHBondContact O-CG2 3.47Å; G482-V486 PolarHBondContact O-N 3.17Å; H483-V486 PolarHBondContact O-N 3.41Å; L484-V486 PolarHBondContact O-N 2.88Å; V486-L488 PolarHBondContact O-N 3.37Å; V486-V489 PolarHBondContact O-N 3.37Å; V486-Y490 HydrophobicContact CG1-CD2 3.53Å; V486-Y490 HydrophobicContact CG1-CE2 3.21Å; V486-Y490 WeakPolarHBondContact O-CD2 3.3Å; V486-Y490 PolarHBondContact O-N 2.88Å; V486-A513 HydrophobicContact CG1-CB 4.28Å
487G97.6Very high94.7Very high0 Ų033.7 Ų33.70%017%0.167CC..Hα-helixtrans-59.5-44.9176.700000112.5H483 L484 A485 Y490 S491 A510 F514H483-G487 PolarHBondContact O-N 3.36Å; L484-G487 WeakPolarHBondContact O-CA 3.09Å; L484-G487 PolarHBondContact O-N 3.17Å; L484-G487 VanDerWaalsContact O-N 3.12Å; A485-G487 VanDerWaalsContact C-N 3.32Å; A485-G487 PolarHBondContact O-N 2.9Å; G487-Y490 PolarHBondContact O-N 3.14Å; G487-S491 WeakPolarHBondContact O-CB 3.29Å; G487-S491 PolarHBondContact O-N 2.87Å; G487-A510 WeakPolarHBondContact O-CB 3.48Å; G487-F514 WeakPolarHBondContact O-CZ 3.34Å
488L97.9Very high95.1Very high1 Ų130 Ų301%0.00516%0.16CC..Hα-helixtrans-62.5-45.7176.4-71.3167.8000112I452 L484 A485 V486 Y490 S491 L492 F514 Y530 R852 L854I452-L488 HydrophobicContact CD1-CB 4.12Å; I452-L488 HydrophobicContact CD1-CD1 4.13Å; L484-L488 HydrophobicContact CG-CD1 4.46Å; L484-L488 WeakPolarHBondContact O-CG 3.44Å; L484-L488 PolarHBondContact O-N 3.36Å; A485-L488 PolarHBondContact O-N 3.33Å; V486-L488 PolarHBondContact O-N 3.37Å; L488-Y490 PolarHBondContact O-N 3.45Å; L488-S491 PolarHBondContact O-N 3.2Å; L488-L492 WeakPolarHBondContact O-CG 3.39Å; L488-L492 PolarHBondContact O-N 3.27Å; L488-F514 HydrophobicContact CD2-CE1 4.32Å; L488-F514 HydrophobicContact CD2-CZ 4.07Å; L488-F514 HydrophobicContact CG-CE1 4.05Å; L488-F514 HydrophobicContact CG-CZ 4.11Å; L488-Y530 HydrophobicContact CD1-CD2 4.43Å; L488-Y530 HydrophobicContact CD1-CE2 4.12Å; L488-Y530 HydrophobicContact CD2-CD1 3.58Å; L488-Y530 HydrophobicContact CD2-CD2 4.07Å; L488-Y530 HydrophobicContact CD2-CE1 3.53Å; L488-Y530 HydrophobicContact CD2-CE2 3.99Å; L488-Y530 HydrophobicContact CD2-CG 3.87Å; L488-R852 HydrophobicContact CD2-CB 3.91Å; L488-R852 HydrophobicContact CD2-CG 4.44Å; L488-L854 HydrophobicContact CD1-CD2 3.71Å; L488-L854 HydrophobicContact CD1-CG 3.63Å
489V98.1Very high95.1Very high0 Ų031.7 Ų31.70%017%0.172CC..Hα-helixtrans-57.3-48.7176.1172.10000110.8V448 I452 L458 E462 A485 V486 S491 L492 K493V448-V489 HydrophobicContact CG1-CG2 4.23Å; I452-V489 HydrophobicContact CG2-CG2 3.49Å; I452-V489 VanDerWaalsContact CG2-CG2 3.49Å; L458-V489 HydrophobicContact CB-CG1 4.43Å; L458-V489 VanDerWaalsContact O-CG1 3.29Å; L458-V489 WeakPolarHBondContact O-CG1 3.17Å; E462-V489 HydrophobicContact CB-CG1 3.92Å; A485-V489 WeakPolarHBondContact O-CG2 3.41Å; A485-V489 PolarHBondContact O-N 2.87Å; V486-V489 PolarHBondContact O-N 3.37Å; V489-S491 PolarHBondContact O-N 3.45Å; V489-L492 PolarHBondContact O-N 2.89Å; V489-K493 HydrophobicContact CG1-CD 4.21Å; V489-K493 HydrophobicContact CG1-CG 4.43Å; V489-K493 WeakPolarHBondContact O-CG 3.35Å; V489-K493 PolarHBondContact O-N 2.78Å
490Y98.3Very high94.9Very high27 Ų2733 Ų3311%0.10618%0.175CC..Hα-helixtrans-67.2-35.9178.9-71.8-44.9000112.8E462 V486 G487 L488 L492 K493 A494 Y506 K509E462-Y490 PolarHBondContact OE1-OH 3.07Å; V486-Y490 HydrophobicContact CG1-CD2 3.53Å; V486-Y490 HydrophobicContact CG1-CE2 3.21Å; V486-Y490 WeakPolarHBondContact O-CD2 3.3Å; V486-Y490 PolarHBondContact O-N 2.88Å; G487-Y490 PolarHBondContact O-N 3.14Å; L488-Y490 PolarHBondContact O-N 3.45Å; Y490-L492 VanDerWaalsContact C-N 3.33Å; Y490-L492 PolarHBondContact O-N 3.43Å; Y490-K493 HydrophobicContact CD1-CD 4.38Å; Y490-K493 PolarHBondContact O-N 2.85Å; Y490-A494 WeakPolarHBondContact O-CB 3.34Å; Y490-A494 PolarHBondContact O-N 3.23Å; Y490-Y506 AromaticContact CD1-CD1 3.67Å; Y490-Y506 HydrophobicContact CD1-CD1 3.67Å; Y490-Y506 HydrophobicContact CD1-CE1 4.06Å; Y490-Y506 HydrophobicContact CE1-CD1 4.24Å; Y490-Y506 HydrophobicContact CE1-CE1 4.26Å; Y490-K509 HydrophobicContact CD1-CB 4.41Å; Y490-K509 HydrophobicContact CD1-CD 4.48Å; Y490-K509 HydrophobicContact CD2-CB 3.63Å; Y490-K509 HydrophobicContact CE1-CD 4.22Å; Y490-K509 HydrophobicContact CE2-CB 3.9Å; Y490-K509 HydrophobicContact CE2-CD 4.49Å; Y490-K509 HydrophobicContact CG-CB 3.9Å
491S97.6Very high94.8Very high5 Ų536.6 Ų36.64%0.03520%0.2CC..Hα-helixtrans-60.5-44.5174.6-171.20000111.3G487 L488 V489 A494 T495 Q534 R852G487-S491 WeakPolarHBondContact O-CB 3.29Å; G487-S491 PolarHBondContact O-N 2.87Å; L488-S491 PolarHBondContact O-N 3.2Å; V489-S491 PolarHBondContact O-N 3.45Å; S491-A494 WeakPolarHBondContact O-CB 3.45Å; S491-A494 PolarHBondContact O-N 3.33Å; S491-T495 PolarHBondContact O-N 3.32Å; S491-T495 PolarHBondContact O-OG1 3.18Å; S491-Q534 PolarHBondContact OG-OE1 2.63Å; S491-R852 PolarHBondContact O-NH1 3.45Å; S491-R852 WeakPolarHBondContact OG-CD 3.47Å; S491-R852 PolarHBondContact OG-NH1 3.1Å
492L96.9Very high94.8Very high17 Ų1734.3 Ų34.39%0.08919%0.194CC..Hα-helixtrans-65.7-45.7175.9-71166.2000111.5I452 L458 L488 V489 Y490 A494 T495 D496 R852I452-L492 HydrophobicContact CB-CD1 3.8Å; I452-L492 HydrophobicContact CG2-CD1 4.29Å; L458-L492 HydrophobicContact CD1-CB 3.84Å; L458-L492 HydrophobicContact CD2-CB 3.8Å; L458-L492 HydrophobicContact CD2-CD1 3.85Å; L458-L492 HydrophobicContact CD2-CG 4.46Å; L488-L492 WeakPolarHBondContact O-CG 3.39Å; L488-L492 PolarHBondContact O-N 3.27Å; V489-L492 PolarHBondContact O-N 2.89Å; Y490-L492 VanDerWaalsContact C-N 3.33Å; Y490-L492 PolarHBondContact O-N 3.43Å; L492-A494 PolarHBondContact O-N 3.01Å; L492-T495 WeakPolarHBondContact O-CA 3.36Å; L492-T495 WeakPolarHBondContact O-CB 3.28Å; L492-T495 PolarHBondContact O-N 3.25Å; L492-D496 PolarHBondContact O-N 3.26Å; L492-D496 VanDerWaalsContact O-N 3.11Å; L492-R852 HydrophobicContact CD2-CB 4.22Å; L492-R852 HydrophobicContact CG-CB 4.39Å
493K97Very high94.7Very high15 Ų1535 Ų357%0.06520%0.197CC..Hα-helixtrans-58.4-34.4174.3-75.3-173.8169.5-162.80112.6L458 D459 E462 V489 Y490 T495 D496 A497 Y506L458-K493 HydrophobicContact CB-CG 3.91Å; L458-K493 HydrophobicContact CD1-CB 4.45Å; L458-K493 HydrophobicContact CD1-CG 3.72Å; L458-K493 HydrophobicContact CG-CG 4.47Å; D459-K493 VanDerWaalsContact OD1-CE 3.3Å; D459-K493 WeakPolarHBondContact OD1-CE 3.45Å; D459-K493 IonicContact OD1-NZ 2.93Å; D459-K493 PolarHBondContact OD1-NZ 2.96Å; E462-K493 IonicContact OE2-NZ 2.84Å; E462-K493 PolarHBondContact OE2-NZ 3.1Å; V489-K493 HydrophobicContact CG1-CD 4.21Å; V489-K493 HydrophobicContact CG1-CG 4.43Å; V489-K493 WeakPolarHBondContact O-CG 3.35Å; V489-K493 PolarHBondContact O-N 2.78Å; Y490-K493 HydrophobicContact CD1-CD 4.38Å; Y490-K493 PolarHBondContact O-N 2.85Å; K493-T495 VanDerWaalsContact C-N 3.26Å; K493-T495 PolarHBondContact O-N 3.06Å; K493-D496 PolarHBondContact O-N 3Å; K493-A497 VanDerWaalsContact O-CB 3.28Å; K493-A497 WeakPolarHBondContact O-CB 3.3Å; K493-A497 PolarHBondContact O-N 2.79Å; K493-Y506 HydrophobicContact CB-CD1 4.24Å; K493-Y506 HydrophobicContact CB-CD2 4Å; K493-Y506 HydrophobicContact CB-CE1 4.36Å; K493-Y506 HydrophobicContact CB-CE2 4.13Å; K493-Y506 HydrophobicContact CB-CG 4.07Å; K493-Y506 HydrophobicContact CD-CE1 4.07Å
494A95.8Very high94.5Very high8 Ų837.6 Ų37.67%0.06621%0.209CC..Hα-helixtrans-67.2-27.4174.400000112.8Y490 S491 L492 Q503 Q507Y490-A494 WeakPolarHBondContact O-CB 3.34Å; Y490-A494 PolarHBondContact O-N 3.23Å; S491-A494 WeakPolarHBondContact O-CB 3.45Å; S491-A494 PolarHBondContact O-N 3.33Å; L492-A494 PolarHBondContact O-N 3.01Å; A494-Q503 WeakPolarHBondContact O-CG 3.08Å; A494-Q507 HydrophobicContact CB-CG 3.83Å
495T93Very high94.5Very high76 Ų7640 Ų4047%0.46622%0.222SC..Hα-helixtrans-78.3-36.3176-51.70000111.7S491 L492 K493 R852S491-T495 PolarHBondContact O-N 3.32Å; S491-T495 PolarHBondContact O-OG1 3.18Å; L492-T495 WeakPolarHBondContact O-CA 3.36Å; L492-T495 WeakPolarHBondContact O-CB 3.28Å; L492-T495 PolarHBondContact O-N 3.25Å; K493-T495 VanDerWaalsContact C-N 3.26Å; K493-T495 PolarHBondContact O-N 3.06Å; T495-R852 PolarHBondContact OG1-NH1 3.11Å; T495-R852 PolarHBondContact OG1-NH2 2.77Å
496D92.6Very high94.5Very high91 Ų9143.1 Ų43.149%0.48723%0.234SC..Hα-helixtrans-79.2-21.2178.8-69.4-0.5000113.6H456 L458 L492 K493 S498H456-D496 IonicContact CD2-OD2 3.86Å; H456-D496 IonicContact CE1-OD1 2.85Å; H456-D496 IonicContact CE1-OD2 3.85Å; H456-D496 PolarHBondContact CE1-OD2 3.38Å; H456-D496 IonicContact NE2-OD1 2.84Å; H456-D496 PolarHBondContact NE2-OD1 3.41Å; H456-D496 IonicContact NE2-OD2 2.65Å; H456-D496 PolarHBondContact NE2-OD2 3.47Å; L458-D496 WeakPolarHBondContact CD1-OD2 3.29Å; L492-D496 PolarHBondContact O-N 3.26Å; L492-D496 VanDerWaalsContact O-N 3.11Å; K493-D496 PolarHBondContact O-N 3Å; D496-S498 PolarHBondContact O-N 2.99Å
497A93.1Very high94.4Very high15 Ų1545.1 Ų45.112%0.12424%0.243CC..  trans-62.7129.8-177.300000111.2K493 Q503 Y506K493-A497 VanDerWaalsContact O-CB 3.28Å; K493-A497 WeakPolarHBondContact O-CB 3.3Å; K493-A497 PolarHBondContact O-N 2.79Å; A497-Q503 HydrophobicContact CB-CB 4.47Å; A497-Q503 HydrophobicContact CB-CG 3.65Å; A497-Q503 WeakPolarHBondContact O-CG 3.46Å; A497-Q503 PolarHBondContact O-NE2 3.32Å; A497-Y506 HydrophobicContact CB-CD2 4.22Å; A497-Y506 HydrophobicContact CB-CE2 4.5Å
498S87.5Confident94.4Very high93 Ų9352.2 Ų52.265%0.6527%0.27SS*.SBendtrans-84.9-23.4-177.461.20000114.1D496D496-S498 PolarHBondContact O-N 2.99Å
499L89.8Confident94.4Very high98 Ų9856 Ų5651%0.51329%0.286SS..SBendtrans-103.3130.7-178.1-62.7172.5000110.1S501 T502 Q503L499-S501 VanDerWaalsContact C-N 3.28Å; L499-S501 PolarHBondContact O-N 3.5Å; L499-T502 HydrophobicContact CB-CG2 4.23Å; L499-T502 HydrophobicContact CD1-CG2 4.49Å; L499-T502 PolarHBondContact O-N 3.26Å; L499-T502 PolarHBondContact O-OG1 3.19Å; L499-Q503 WeakPolarHBondContact O-CG 3.3Å; L499-Q503 PolarHBondContact O-N 3.02Å
500R87.6Confident94.4Very high109 Ų10956 Ų5641%0.41129%0.286SS..Hα-helixtrans-51-43.4177.6-177.8178.3169.4172.31.8113.7T502 Q503 E504R500-T502 VanDerWaalsContact C-N 3.29Å; R500-T502 PolarHBondContact O-N 3.03Å; R500-Q503 WeakPolarHBondContact O-CB 3.48Å; R500-Q503 PolarHBondContact O-N 3.44Å; R500-E504 HydrophobicContact CG-CG 4.44Å; R500-E504 WeakPolarHBondContact CG-OE1 3.43Å; R500-E504 IonicContact CZ-OE1 3.24Å; R500-E504 IonicContact NE-OE1 3.61Å; R500-E504 PolarHBondContact NE-OE1 3.36Å; R500-E504 IonicContact NH2-OE1 2.86Å; R500-E504 PolarHBondContact NH2-OE1 3.28Å; R500-E504 WeakPolarHBondContact O-CG 3.48Å; R500-E504 PolarHBondContact O-N 2.85Å
501S91.1Very high94.4Very high82 Ų8256 Ų5657%0.57329%0.288SS*.Hα-helixtrans-61.3-37.417957.30000112.9L499 D505L499-S501 VanDerWaalsContact C-N 3.28Å; L499-S501 PolarHBondContact O-N 3.5Å; S501-D505 PolarHBondContact O-N 3.38Å; S501-D505 VanDerWaalsContact O-N 3.12Å
502T94Very high94.4Very high50 Ų5057.9 Ų57.931%0.30730%0.301SS..Hα-helixtrans-74.6-36.1176.558.70000112.2L499 R500 D505 Y506L499-T502 HydrophobicContact CB-CG2 4.23Å; L499-T502 HydrophobicContact CD1-CG2 4.49Å; L499-T502 PolarHBondContact O-N 3.26Å; L499-T502 PolarHBondContact O-OG1 3.19Å; R500-T502 VanDerWaalsContact C-N 3.29Å; R500-T502 PolarHBondContact O-N 3.03Å; T502-D505 PolarHBondContact O-N 3.39Å; T502-Y506 WeakPolarHBondContact O-CD2 3.5Å; T502-Y506 PolarHBondContact O-N 3.4Å
503Q92.6Very high94.4Very high14 Ų1457.4 Ų57.47%0.06530%0.3CS..Hα-helixtrans-59.5-49.6172.5-63.6169.1-2.200110.3A494 A497 L499 R500 D505 Y506 Q507 Q803A494-Q503 WeakPolarHBondContact O-CG 3.08Å; A497-Q503 HydrophobicContact CB-CB 4.47Å; A497-Q503 HydrophobicContact CB-CG 3.65Å; A497-Q503 WeakPolarHBondContact O-CG 3.46Å; A497-Q503 PolarHBondContact O-NE2 3.32Å; L499-Q503 WeakPolarHBondContact O-CG 3.3Å; L499-Q503 PolarHBondContact O-N 3.02Å; R500-Q503 WeakPolarHBondContact O-CB 3.48Å; R500-Q503 PolarHBondContact O-N 3.44Å; Q503-D505 PolarHBondContact O-N 3.26Å; Q503-Y506 PolarHBondContact O-N 2.75Å; Q503-Q507 WeakPolarHBondContact O-CB 3.06Å; Q503-Q507 VanDerWaalsContact O-CG 3.29Å; Q503-Q507 WeakPolarHBondContact O-CG 3.26Å; Q503-Q507 PolarHBondContact O-N 2.89Å; Q503-Q803 PolarHBondContact NE2-O 3.41Å
504E93.4Very high94.5Very high76 Ų7656.9 Ų56.936%0.35530%0.297SS..Hα-helixtrans-62.3-38.9179.2-71.4173.2-174.900112.4R500 R508R500-E504 HydrophobicContact CG-CG 4.44Å; R500-E504 WeakPolarHBondContact CG-OE1 3.43Å; R500-E504 IonicContact CZ-OE1 3.24Å; R500-E504 IonicContact NE-OE1 3.61Å; R500-E504 PolarHBondContact NE-OE1 3.36Å; R500-E504 IonicContact NH2-OE1 2.86Å; R500-E504 PolarHBondContact NH2-OE1 3.28Å; R500-E504 WeakPolarHBondContact O-CG 3.48Å; R500-E504 PolarHBondContact O-N 2.85Å; E504-R508 WeakPolarHBondContact O-CB 3.34Å; E504-R508 PolarHBondContact O-N 2.95Å
505D96.4Very high94.5Very high55 Ų5560.7 Ų60.729%0.29431%0.314SS..Hα-helixtrans-65-46.2175.4-174.746.1000112.2S501 T502 Q503 R508 K509S501-D505 PolarHBondContact O-N 3.38Å; S501-D505 VanDerWaalsContact O-N 3.12Å; T502-D505 PolarHBondContact O-N 3.39Å; Q503-D505 PolarHBondContact O-N 3.26Å; D505-R508 PolarHBondContact O-N 3.14Å; D505-R508 IonicContact OD1-NH1 3.22Å; D505-R508 PolarHBondContact OD1-NH1 3.3Å; D505-K509 WeakPolarHBondContact O-CG 3.41Å; D505-K509 PolarHBondContact O-N 3.1Å; D505-K509 IonicContact OD1-NZ 3.16Å; D505-K509 VanDerWaalsContact OD2-CE 3.3Å; D505-K509 WeakPolarHBondContact OD2-CE 3.35Å; D505-K509 IonicContact OD2-NZ 3.4Å; D505-K509 PolarHBondContact OD2-NZ 2.86Å
506Y97.4Very high94.7Very high65 Ų6563.7 Ų63.726%0.25532%0.317SS..Hα-helixtrans-66.3-38.3176.7-73.5-49000112.6Y490 K493 A497 T502 Q503 R508 K509 A510Y490-Y506 AromaticContact CD1-CD1 3.67Å; Y490-Y506 HydrophobicContact CD1-CD1 3.67Å; Y490-Y506 HydrophobicContact CD1-CE1 4.06Å; Y490-Y506 HydrophobicContact CE1-CD1 4.24Å; Y490-Y506 HydrophobicContact CE1-CE1 4.26Å; K493-Y506 HydrophobicContact CB-CD1 4.24Å; K493-Y506 HydrophobicContact CB-CD2 4Å; K493-Y506 HydrophobicContact CB-CE1 4.36Å; K493-Y506 HydrophobicContact CB-CE2 4.13Å; K493-Y506 HydrophobicContact CB-CG 4.07Å; K493-Y506 HydrophobicContact CD-CE1 4.07Å; A497-Y506 HydrophobicContact CB-CD2 4.22Å; A497-Y506 HydrophobicContact CB-CE2 4.5Å; T502-Y506 WeakPolarHBondContact O-CD2 3.5Å; T502-Y506 PolarHBondContact O-N 3.4Å; Q503-Y506 PolarHBondContact O-N 2.75Å; Y506-R508 VanDerWaalsContact C-N 3.34Å; Y506-R508 PolarHBondContact O-N 2.71Å; Y506-K509 HydrophobicContact CD1-CD 4.32Å; Y506-K509 PolarHBondContact O-N 2.88Å; Y506-A510 WeakPolarHBondContact O-CB 3.21Å; Y506-A510 PolarHBondContact O-N 3.43Å
507Q95.8Very high94.8Very high50 Ų5059.4 Ų59.423%0.23429%0.293CS..Hα-helixtrans-60.1-43173.3-75.1176.1-2.200111.7A494 Q503 A510 L511A494-Q507 HydrophobicContact CB-CG 3.83Å; Q503-Q507 WeakPolarHBondContact O-CB 3.06Å; Q503-Q507 VanDerWaalsContact O-CG 3.29Å; Q503-Q507 WeakPolarHBondContact O-CG 3.26Å; Q503-Q507 PolarHBondContact O-N 2.89Å; Q507-A510 PolarHBondContact O-N 3.5Å; Q507-L511 WeakPolarHBondContact O-CB 3.44Å; Q507-L511 PolarHBondContact O-N 3.38Å
508R97Very high94.9Very high149 Ų14959.3 Ų59.356%0.56229%0.29SS*.Hα-helixtrans-63.5-42.4176.5-167.2-172.9-55.7106.94111.9E504 D505 Y506 L511 S512E504-R508 WeakPolarHBondContact O-CB 3.34Å; E504-R508 PolarHBondContact O-N 2.95Å; D505-R508 PolarHBondContact O-N 3.14Å; D505-R508 IonicContact OD1-NH1 3.22Å; D505-R508 PolarHBondContact OD1-NH1 3.3Å; Y506-R508 VanDerWaalsContact C-N 3.34Å; Y506-R508 PolarHBondContact O-N 2.71Å; R508-L511 PolarHBondContact O-N 3.43Å; R508-S512 PolarHBondContact O-N 2.83Å
509K97.8Very high95.3Very high81 Ų8159 Ų5935%0.35229%0.289SS..Hα-helixtrans-64.3-42.6175.7-73.8170176.1162.80111.9Y490 D505 Y506 S512 A513Y490-K509 HydrophobicContact CD1-CB 4.41Å; Y490-K509 HydrophobicContact CD1-CD 4.48Å; Y490-K509 HydrophobicContact CD2-CB 3.63Å; Y490-K509 HydrophobicContact CE1-CD 4.22Å; Y490-K509 HydrophobicContact CE2-CB 3.9Å; Y490-K509 HydrophobicContact CE2-CD 4.49Å; Y490-K509 HydrophobicContact CG-CB 3.9Å; D505-K509 WeakPolarHBondContact O-CG 3.41Å; D505-K509 PolarHBondContact O-N 3.1Å; D505-K509 IonicContact OD1-NZ 3.16Å; D505-K509 VanDerWaalsContact OD2-CE 3.3Å; D505-K509 WeakPolarHBondContact OD2-CE 3.35Å; D505-K509 IonicContact OD2-NZ 3.4Å; D505-K509 PolarHBondContact OD2-NZ 2.86Å; Y506-K509 HydrophobicContact CD1-CD 4.32Å; Y506-K509 PolarHBondContact O-N 2.88Å; K509-S512 PolarHBondContact O-N 3.14Å; K509-A513 WeakPolarHBondContact O-CB 3.37Å; K509-A513 PolarHBondContact O-N 2.84Å
510A98.1Very high95.4Very high0 Ų058.2 Ų58.20%028%0.283CS..Hα-helixtrans-60.6-49.6175.800000111.1G487 Y506 Q507 S512 A513 F514 Q534G487-A510 WeakPolarHBondContact O-CB 3.48Å; Y506-A510 WeakPolarHBondContact O-CB 3.21Å; Y506-A510 PolarHBondContact O-N 3.43Å; Q507-A510 PolarHBondContact O-N 3.5Å; A510-S512 PolarHBondContact O-N 3.36Å; A510-A513 PolarHBondContact O-N 3.08Å; A510-A513 VanDerWaalsContact O-N 3.15Å; A510-F514 HydrophobicContact CB-CE2 4.18Å; A510-F514 WeakPolarHBondContact O-CD2 3.42Å; A510-F514 WeakPolarHBondContact O-CG 3.34Å; A510-F514 PolarHBondContact O-N 3.32Å; A510-Q534 HydrophobicContact CB-CG 4.21Å
511L97.6Very high95.6Very high28 Ų2854.4 Ų54.415%0.14727%0.274CS..Hα-helixtrans-59.1-46.8178.7-170.971.4000111.8Q507 R508 A513 F514 Q515 L531 Q534 L535Q507-L511 WeakPolarHBondContact O-CB 3.44Å; Q507-L511 PolarHBondContact O-N 3.38Å; R508-L511 PolarHBondContact O-N 3.43Å; L511-A513 VanDerWaalsContact C-N 3.3Å; L511-A513 PolarHBondContact O-N 2.71Å; L511-F514 PolarHBondContact O-N 3.22Å; L511-Q515 WeakPolarHBondContact O-CB 3.29Å; L511-Q515 VanDerWaalsContact O-CG 3.28Å; L511-Q515 WeakPolarHBondContact O-CG 3.22Å; L511-Q515 PolarHBondContact O-N 3.36Å; L511-L531 HydrophobicContact CD1-CD1 3.67Å; L511-Q534 HydrophobicContact CB-CG 4.33Å; L511-Q534 HydrophobicContact CD1-CG 4.24Å; L511-L535 HydrophobicContact CD1-CD2 3.56Å; L511-L535 HydrophobicContact CD1-CG 3.77Å; L511-L535 HydrophobicContact CD2-CD2 4.39Å
512S97.9Very high95.7Very high44 Ų4453.8 Ų53.831%0.30827%0.267SS..Hα-helixtrans-61-39176.9-173.70000112.2R508 K509 A510 R516R508-S512 PolarHBondContact O-N 2.83Å; K509-S512 PolarHBondContact O-N 3.14Å; A510-S512 PolarHBondContact O-N 3.36Å; S512-R516 VanDerWaalsContact O-CG 3.3Å; S512-R516 WeakPolarHBondContact O-CG 3.48Å; S512-R516 PolarHBondContact O-N 3.06Å; S512-R516 VanDerWaalsContact O-N 3.08Å
513A97.4Very high95.7Very high7 Ų756.7 Ų56.76%0.05829%0.285CS..Hα-helixtrans-67.8-43.5178.300000112V486 K509 A510 L511 R516 A517V486-A513 HydrophobicContact CG1-CB 4.28Å; K509-A513 WeakPolarHBondContact O-CB 3.37Å; K509-A513 PolarHBondContact O-N 2.84Å; A510-A513 PolarHBondContact O-N 3.08Å; A510-A513 VanDerWaalsContact O-N 3.15Å; L511-A513 VanDerWaalsContact C-N 3.3Å; L511-A513 PolarHBondContact O-N 2.71Å; A513-R516 PolarHBondContact O-N 3.47Å; A513-A517 PolarHBondContact O-N 3.39Å
514F97.8Very high95.7Very high3 Ų357.2 Ų57.21%0.01329%0.289CS..Hα-helixtrans-65.8-40.6176-66.4-48.4000112.8L484 G487 L488 A510 L511 R516 A517 Q518 Y530 L531 Q534L484-F514 HydrophobicContact CD1-CD1 3.75Å; L484-F514 HydrophobicContact CD1-CE1 3.76Å; L484-F514 WeakPolarHBondContact O-CE1 3.43Å; G487-F514 WeakPolarHBondContact O-CZ 3.34Å; L488-F514 HydrophobicContact CD2-CE1 4.32Å; L488-F514 HydrophobicContact CD2-CZ 4.07Å; L488-F514 HydrophobicContact CG-CE1 4.05Å; L488-F514 HydrophobicContact CG-CZ 4.11Å; A510-F514 HydrophobicContact CB-CE2 4.18Å; A510-F514 WeakPolarHBondContact O-CD2 3.42Å; A510-F514 WeakPolarHBondContact O-CG 3.34Å; A510-F514 PolarHBondContact O-N 3.32Å; L511-F514 PolarHBondContact O-N 3.22Å; F514-R516 VanDerWaalsContact C-N 3.31Å; F514-R516 PolarHBondContact O-N 3.48Å; F514-A517 WeakPolarHBondContact O-CB 3.44Å; F514-A517 PolarHBondContact O-N 3.19Å; F514-Q518 WeakPolarHBondContact O-CB 3.24Å; F514-Q518 PolarHBondContact O-N 3.46Å; F514-Y530 HydrophobicContact CE1-CG 4.33Å; F514-L531 HydrophobicContact CB-CB 3.97Å; F514-L531 HydrophobicContact CB-CD1 3.95Å; F514-Q534 HydrophobicContact CD2-CB 3.68Å; F514-Q534 HydrophobicContact CD2-CG 3.96Å; F514-Q534 HydrophobicContact CE2-CB 3.79Å; F514-Q534 HydrophobicContact CE2-CG 4.04Å
515Q97.3Very high95.8Very high89 Ų8955.6 Ų55.642%0.41628%0.281SS..Hα-helixtrans-59.6-42.1173.6-73.7172.4-17.800111.7L511 Q518 S519 L531L511-Q515 WeakPolarHBondContact O-CB 3.29Å; L511-Q515 VanDerWaalsContact O-CG 3.28Å; L511-Q515 WeakPolarHBondContact O-CG 3.22Å; L511-Q515 PolarHBondContact O-N 3.36Å; Q515-Q518 PolarHBondContact O-N 3.4Å; Q515-S519 WeakPolarHBondContact O-CB 3.21Å; Q515-S519 PolarHBondContact O-N 3.48Å; Q515-S519 PolarHBondContact O-OG 3.36Å; Q515-L531 HydrophobicContact CG-CD1 3.71Å; Q515-L531 HydrophobicContact CG-CD2 4.27Å
516R95.9Very high95.7Very high139 Ų13955.5 Ų55.553%0.52528%0.28SS..Hα-helixtrans-63.3-46.8174.4-72.1178.8-157.8-146.74.9111.4H483 S512 A513 F514 Q518 S519 M520H483-R516 HydrophobicContact CB-CB 4.5Å; S512-R516 VanDerWaalsContact O-CG 3.3Å; S512-R516 WeakPolarHBondContact O-CG 3.48Å; S512-R516 PolarHBondContact O-N 3.06Å; S512-R516 VanDerWaalsContact O-N 3.08Å; A513-R516 PolarHBondContact O-N 3.47Å; F514-R516 VanDerWaalsContact C-N 3.31Å; F514-R516 PolarHBondContact O-N 3.48Å; R516-Q518 VanDerWaalsContact C-N 3.33Å; R516-Q518 PolarHBondContact O-N 3.27Å; R516-S519 WeakPolarHBondContact CA-OG 3.34Å; R516-S519 PolarHBondContact O-N 2.8Å; R516-S519 PolarHBondContact O-OG 3.04Å; R516-M520 HydrophobicContact CB-CE 4.23Å; R516-M520 VanDerWaalsContact O-CE 3.29Å; R516-M520 WeakPolarHBondContact O-CE 3.36Å; R516-M520 WeakPolarHBondContact O-CG 3.4Å; R516-M520 PolarHBondContact O-N 2.93Å
517A95.3Very high95.6Very high0 Ų052.5 Ų52.50%027%0.268CS..Hα-helixtrans-55-49.117700000111.1A480 H483 L484 A513 F514 S519 M520 S521 A527A480-A517 WeakPolarHBondContact O-CB 3.43Å; H483-A517 HydrophobicContact CB-CB 4.01Å; L484-A517 HydrophobicContact CB-CB 4.14Å; A513-A517 PolarHBondContact O-N 3.39Å; F514-A517 WeakPolarHBondContact O-CB 3.44Å; F514-A517 PolarHBondContact O-N 3.19Å; A517-S519 PolarHBondContact O-N 2.76Å; A517-M520 PolarHBondContact O-N 3.44Å; A517-S521 PolarHBondContact O-N 3.04Å; A517-A527 HydrophobicContact CB-CB 4.23Å
518Q95.4Very high95.7Very high13 Ų1350.1 Ų50.16%0.06126%0.257CS..Hα-helixtrans-65.5-36.3178.9-17559.39.400113.1F514 Q515 R516 M520 S521 P522 A527 L531 Y547F514-Q518 WeakPolarHBondContact O-CB 3.24Å; F514-Q518 PolarHBondContact O-N 3.46Å; Q515-Q518 PolarHBondContact O-N 3.4Å; R516-Q518 VanDerWaalsContact C-N 3.33Å; R516-Q518 PolarHBondContact O-N 3.27Å; Q518-M520 VanDerWaalsContact C-N 3.33Å; Q518-M520 PolarHBondContact O-N 3.49Å; Q518-S521 CarbonylContact O-C 3.59Å; Q518-P522 WeakPolarHBondContact O-CA 3.38Å; Q518-A527 HydrophobicContact CB-CB 4.4Å; Q518-A527 VanDerWaalsContact OE1-CB 3.28Å; Q518-L531 HydrophobicContact CB-CD2 4.12Å; Q518-L531 HydrophobicContact CG-CD2 4.26Å; Q518-Y547 HydrophobicContact CG-CE1 4.46Å
519S94.7Very high95.7Very high88 Ų8843 Ų4362%0.61523%0.231SC*.Hα-helixtrans-68.4-32.7177.271.70000113Q515 R516 A517Q515-S519 WeakPolarHBondContact O-CB 3.21Å; Q515-S519 PolarHBondContact O-N 3.48Å; Q515-S519 PolarHBondContact O-OG 3.36Å; R516-S519 WeakPolarHBondContact CA-OG 3.34Å; R516-S519 PolarHBondContact O-N 2.8Å; R516-S519 PolarHBondContact O-OG 3.04Å; A517-S519 PolarHBondContact O-N 2.76Å
520M93.3Very high95.7Very high80 Ų8039.9 Ų39.939%0.39422%0.217SC..Hα-helixtrans-83.6-33.1179.5-67.4-177.7-71.700112.4K479 A480 H483 R516 A517 Q518K479-M520 HydrophobicContact CD-SD 4.45Å; K479-M520 HydrophobicContact CG-SD 4.17Å; A480-M520 HydrophobicContact CB-CB 4.06Å; A480-M520 HydrophobicContact CB-CE 4.45Å; H483-M520 HydrophobicContact CB-CE 3.84Å; H483-M520 WeakPolarHBondContact CD2-CE 3.22Å; R516-M520 HydrophobicContact CB-CE 4.23Å; R516-M520 VanDerWaalsContact O-CE 3.29Å; R516-M520 WeakPolarHBondContact O-CE 3.36Å; R516-M520 WeakPolarHBondContact O-CG 3.4Å; R516-M520 PolarHBondContact O-N 2.93Å; A517-M520 PolarHBondContact O-N 3.44Å; Q518-M520 VanDerWaalsContact C-N 3.33Å; Q518-M520 PolarHBondContact O-N 3.49Å
521S92.5Very high95.7Very high30 Ų3039.9 Ų39.921%0.2122%0.217CC..  trans-132.181.3176.4-164.10000111.4A517 Q518 T523 D524A517-S521 PolarHBondContact O-N 3.04Å; Q518-S521 CarbonylContact O-C 3.59Å; S521-T523 PolarHBondContact O-N 2.91Å; S521-D524 PolarHBondContact O-N 2.77Å
522P92.9Very high95.7Very high68 Ų6838.6 Ų38.644%0.44221%0.21SC..THydrogen-bonded Turntrans-67.2-15.1-180-21.333.4000114.4Q518Q518-P522 WeakPolarHBondContact O-CA 3.38Å
523T92.8Very high95.7Very high112 Ų11236.7 Ų36.769%0.68720%0.196SC*.THydrogen-bonded Turntrans-88.7-11.7179.154.20000113.1S521 H525S521-T523 PolarHBondContact O-N 2.91Å; T523-H525 PolarHBondContact O-N 3.48Å
524D93Very high95.8Very high25 Ų2536.5 Ų36.513%0.13419%0.194CC..  trans-80.2109.9177.7-174.1-3.6000109.8S521 L526 A527 A528S521-D524 PolarHBondContact O-N 2.77Å; D524-L526 PolarHBondContact O-N 3.21Å; D524-L526 WeakPolarHBondContact OD1-CB 3.34Å; D524-L526 PolarHBondContact OD1-N 2.87Å; D524-A527 HydrophobicContact CB-CB 4.13Å; D524-A527 PolarHBondContact O-N 3.37Å; D524-A528 PolarHBondContact O-N 3.21Å
525H95.2Very high95.8Very high41 Ų4136.4 Ų36.419%0.1919%0.194CC..Hα-helixtrans-63.3-30.1179.379.9100.5000112.2T523 A528 F529 L554 Q555T523-H525 PolarHBondContact O-N 3.48Å; H525-A528 PolarHBondContact O-N 3.14Å; H525-F529 WeakPolarHBondContact O-CB 3.33Å; H525-F529 PolarHBondContact O-N 3.48Å; H525-L554 HydrophobicContact CB-CB 3.84Å; H525-L554 HydrophobicContact CB-CD1 4.23Å; H525-Q555 HydrophobicContact CB-CB 4.19Å; H525-Q555 HydrophobicContact CB-CG 3.84Å
526L94.9Very high95.8Very high54 Ų5432.2 Ų32.228%0.28317%0.174SC..Hα-helixtrans-69.1-36.1-179.9-66.1175.6000111.4L484 D524 F529 Y530L484-L526 HydrophobicContact CD2-CB 4.15Å; D524-L526 PolarHBondContact O-N 3.21Å; D524-L526 WeakPolarHBondContact OD1-CB 3.34Å; D524-L526 PolarHBondContact OD1-N 2.87Å; L526-F529 PolarHBondContact O-N 2.95Å; L526-Y530 HydrophobicContact CB-CD2 4.43Å; L526-Y530 WeakPolarHBondContact O-CB 3.32Å; L526-Y530 VanDerWaalsContact O-CD2 3.25Å; L526-Y530 WeakPolarHBondContact O-CD2 3.44Å; L526-Y530 PolarHBondContact O-N 3.4Å
527A95.2Very high95.8Very high1 Ų126.9 Ų26.91%0.00816%0.157CC..Hα-helixtrans-64.8-44.9175.600000111.3A517 Q518 D524 L531A517-A527 HydrophobicContact CB-CB 4.23Å; Q518-A527 HydrophobicContact CB-CB 4.4Å; Q518-A527 VanDerWaalsContact OE1-CB 3.28Å; D524-A527 HydrophobicContact CB-CB 4.13Å; D524-A527 PolarHBondContact O-N 3.37Å; A527-L531 VanDerWaalsContact O-CB 3.26Å; A527-L531 WeakPolarHBondContact O-CB 3.22Å; A527-L531 PolarHBondContact O-N 3.07Å; A527-L531 VanDerWaalsContact O-N 3.08Å
528A96.8Very high95.7Very high0 Ų028.6 Ų28.60%017%0.169CC..Hα-helixtrans-64.1-45.3174.800000111.7D524 H525 L531 A532 A551D524-A528 PolarHBondContact O-N 3.21Å; H525-A528 PolarHBondContact O-N 3.14Å; A528-L531 PolarHBondContact O-N 3.42Å; A528-A532 WeakPolarHBondContact O-CB 3.33Å; A528-A532 PolarHBondContact O-N 2.95Å; A528-A551 HydrophobicContact CB-CB 3.97Å
529F97.8Very high95.7Very high1 Ų130.4 Ų30.40%0.00418%0.175CC..Hα-helixtrans-60.9-51.3179.6167.2-103.4000112.1H525 L526 L531 A532 L533 A551 H560 S561 L564 I850H525-F529 WeakPolarHBondContact O-CB 3.33Å; H525-F529 PolarHBondContact O-N 3.48Å; L526-F529 PolarHBondContact O-N 2.95Å; F529-L531 VanDerWaalsContact C-N 3.35Å; F529-L531 PolarHBondContact O-N 3.41Å; F529-A532 WeakPolarHBondContact O-CB 3.43Å; F529-A532 PolarHBondContact O-N 2.84Å; F529-A532 VanDerWaalsContact O-N 3.15Å; F529-L533 HydrophobicContact CE1-CD2 4.4Å; F529-L533 HydrophobicContact CZ-CD2 4.23Å; F529-L533 PolarHBondContact O-N 3.43Å; F529-A551 HydrophobicContact CB-CB 4.11Å; F529-H560 HydrophobicContact CE1-CB 4.13Å; F529-H560 HydrophobicContact CE2-CB 3.83Å; F529-H560 WeakPolarHBondContact CE2-O 3.31Å; F529-H560 HydrophobicContact CZ-CB 3.64Å; F529-S561 WeakPolarHBondContact CD2-OG 3.23Å; F529-L564 HydrophobicContact CD2-CD2 4.12Å; F529-L564 HydrophobicContact CE2-CB 3.99Å; F529-L564 HydrophobicContact CE2-CD2 3.75Å; F529-I850 HydrophobicContact CE1-CG2 4.47Å; F529-I850 HydrophobicContact CZ-CG2 3.72Å
530Y97.9Very high95.8Very high14 Ų1429.7 Ų29.76%0.05516%0.162CC..Hα-helixtrans-70.9-30.5-178.8-78-56.5000113.2L484 L488 F514 L526 L533 Q534 R852 A853L484-Y530 HydrophobicContact CD1-CD2 3.68Å; L484-Y530 HydrophobicContact CD1-CG 4.23Å; L484-Y530 HydrophobicContact CG-CD2 4.4Å; L488-Y530 HydrophobicContact CD1-CD2 4.43Å; L488-Y530 HydrophobicContact CD1-CE2 4.12Å; L488-Y530 HydrophobicContact CD2-CD1 3.58Å; L488-Y530 HydrophobicContact CD2-CD2 4.07Å; L488-Y530 HydrophobicContact CD2-CE1 3.53Å; L488-Y530 HydrophobicContact CD2-CE2 3.99Å; L488-Y530 HydrophobicContact CD2-CG 3.87Å; F514-Y530 HydrophobicContact CE1-CG 4.33Å; L526-Y530 HydrophobicContact CB-CD2 4.43Å; L526-Y530 WeakPolarHBondContact O-CB 3.32Å; L526-Y530 VanDerWaalsContact O-CD2 3.25Å; L526-Y530 WeakPolarHBondContact O-CD2 3.44Å; L526-Y530 PolarHBondContact O-N 3.4Å; Y530-L533 HydrophobicContact CD1-CD2 4.01Å; Y530-L533 HydrophobicContact CE1-CD2 4.2Å; Y530-L533 PolarHBondContact O-N 3.18Å; Y530-Q534 WeakPolarHBondContact O-CB 3.33Å; Y530-Q534 PolarHBondContact O-N 3.35Å; Y530-R852 HydrophobicContact CE1-CG 4.48Å; Y530-A853 PolarHBondContact OH-N 2.87Å; Y530-A853 VanDerWaalsContact OH-N 3.07Å; Y530-A853 PolarHBondContact OH-O 2.92Å
531L97.9Very high96Very high1 Ų126.5 Ų26.51%0.00515%0.146CC..Hα-helixtrans-60.5-47.8167.8178.154.4000110.7L511 F514 Q515 Q518 A527 A528 F529 L533 Q534 L535 Y547L511-L531 HydrophobicContact CD1-CD1 3.67Å; F514-L531 HydrophobicContact CB-CB 3.97Å; F514-L531 HydrophobicContact CB-CD1 3.95Å; Q515-L531 HydrophobicContact CG-CD1 3.71Å; Q515-L531 HydrophobicContact CG-CD2 4.27Å; Q518-L531 HydrophobicContact CB-CD2 4.12Å; Q518-L531 HydrophobicContact CG-CD2 4.26Å; A527-L531 VanDerWaalsContact O-CB 3.26Å; A527-L531 WeakPolarHBondContact O-CB 3.22Å; A527-L531 PolarHBondContact O-N 3.07Å; A527-L531 VanDerWaalsContact O-N 3.08Å; A528-L531 PolarHBondContact O-N 3.42Å; F529-L531 VanDerWaalsContact C-N 3.35Å; F529-L531 PolarHBondContact O-N 3.41Å; L531-L533 PolarHBondContact O-N 3.49Å; L531-Q534 PolarHBondContact O-N 2.88Å; L531-L535 HydrophobicContact CD1-CD1 4.13Å; L531-L535 HydrophobicContact CD1-CG 4.31Å; L531-L535 HydrophobicContact CG-CD1 4.09Å; L531-L535 WeakPolarHBondContact O-CG 3.25Å; L531-L535 PolarHBondContact O-N 3.4Å; L531-Y547 HydrophobicContact CD2-CD1 3.85Å; L531-Y547 HydrophobicContact CD2-CD2 4.15Å; L531-Y547 HydrophobicContact CD2-CE1 3.58Å; L531-Y547 HydrophobicContact CD2-CE2 3.89Å; L531-Y547 HydrophobicContact CD2-CG 4.12Å; L531-Y547 HydrophobicContact CG-CD1 4.48Å; L531-Y547 HydrophobicContact CG-CD2 4.21Å; L531-Y547 HydrophobicContact CG-CE2 4.29Å; L531-Y547 HydrophobicContact CG-CG 4.3Å
532A98.3Very high96.1Very high0 Ų029.6 Ų29.60%017%0.166CC..Hα-helixtrans-61.7-42.9177.500000112.3A528 F529 Q534 L535 A536 A544 V548 L564A528-A532 WeakPolarHBondContact O-CB 3.33Å; A528-A532 PolarHBondContact O-N 2.95Å; F529-A532 WeakPolarHBondContact O-CB 3.43Å; F529-A532 PolarHBondContact O-N 2.84Å; F529-A532 VanDerWaalsContact O-N 3.15Å; A532-Q534 VanDerWaalsContact C-N 3.34Å; A532-Q534 PolarHBondContact O-N 2.97Å; A532-L535 PolarHBondContact O-N 3.4Å; A532-A536 WeakPolarHBondContact O-CB 3.43Å; A532-A536 PolarHBondContact O-N 2.9Å; A532-A544 WeakPolarHBondContact O-CB 3.33Å; A532-V548 HydrophobicContact CB-CB 4.4Å; A532-V548 HydrophobicContact CB-CG2 3.42Å; A532-V548 VanDerWaalsContact CB-CG2 3.42Å; A532-L564 HydrophobicContact CB-CD2 4.07Å
533L98.3Very high96.3Very high5 Ų531.5 Ų31.53%0.02617%0.169CC..Hα-helixtrans-61.7-43.1176.7-176.662.5000111.1F529 Y530 L531 A536 V537 L564 F847 I850 R852F529-L533 HydrophobicContact CE1-CD2 4.4Å; F529-L533 HydrophobicContact CZ-CD2 4.23Å; F529-L533 PolarHBondContact O-N 3.43Å; Y530-L533 HydrophobicContact CD1-CD2 4.01Å; Y530-L533 HydrophobicContact CE1-CD2 4.2Å; Y530-L533 PolarHBondContact O-N 3.18Å; L531-L533 PolarHBondContact O-N 3.49Å; L533-A536 WeakPolarHBondContact O-CB 3.33Å; L533-A536 PolarHBondContact O-N 2.73Å; L533-V537 WeakPolarHBondContact O-CG2 3.35Å; L533-V537 PolarHBondContact O-N 2.88Å; L533-L564 HydrophobicContact CB-CD2 3.92Å; L533-L564 HydrophobicContact CD1-CD1 3.79Å; L533-L564 HydrophobicContact CD1-CD2 4.19Å; L533-F847 HydrophobicContact CD1-CB 4.09Å; L533-I850 HydrophobicContact CD1-CD1 4.45Å; L533-R852 HydrophobicContact CD2-CG 3.98Å
534Q98.1Very high96.6Very high3 Ų326.2 Ų26.21%0.01414%0.136CC..Hα-helixtrans-67.3-38.8178.6-171.257.458.800112S491 A510 L511 F514 Y530 L531 A532 A536 V537 S538S491-Q534 PolarHBondContact OG-OE1 2.63Å; A510-Q534 HydrophobicContact CB-CG 4.21Å; L511-Q534 HydrophobicContact CB-CG 4.33Å; L511-Q534 HydrophobicContact CD1-CG 4.24Å; F514-Q534 HydrophobicContact CD2-CB 3.68Å; F514-Q534 HydrophobicContact CD2-CG 3.96Å; F514-Q534 HydrophobicContact CE2-CB 3.79Å; F514-Q534 HydrophobicContact CE2-CG 4.04Å; Y530-Q534 WeakPolarHBondContact O-CB 3.33Å; Y530-Q534 PolarHBondContact O-N 3.35Å; L531-Q534 PolarHBondContact O-N 2.88Å; A532-Q534 VanDerWaalsContact C-N 3.34Å; A532-Q534 PolarHBondContact O-N 2.97Å; Q534-A536 VanDerWaalsContact C-N 3.34Å; Q534-V537 PolarHBondContact O-N 3.25Å; Q534-S538 PolarHBondContact O-N 3.27Å; Q534-S538 PolarHBondContact O-OG 3.48Å; Q534-S538 VanDerWaalsContact O-OG 3.05Å
535L98Very high96.8Very high1 Ų125.4 Ų25.41%0.00513%0.132CC..Hα-helixtrans-63.7-39.9172.4-72.3166.4000111.6L511 L531 A532 S538 R539 Q540 E543 A544 Y547L511-L535 HydrophobicContact CD1-CD2 3.56Å; L511-L535 HydrophobicContact CD1-CG 3.77Å; L511-L535 HydrophobicContact CD2-CD2 4.39Å; L531-L535 HydrophobicContact CD1-CD1 4.13Å; L531-L535 HydrophobicContact CD1-CG 4.31Å; L531-L535 HydrophobicContact CG-CD1 4.09Å; L531-L535 WeakPolarHBondContact O-CG 3.25Å; L531-L535 PolarHBondContact O-N 3.4Å; A532-L535 PolarHBondContact O-N 3.4Å; L535-S538 CarbonylContact O-C 3.51Å; L535-S538 PolarHBondContact O-N 3.27Å; L535-R539 PolarHBondContact O-N 3.06Å; L535-Q540 HydrophobicContact CB-CB 4.44Å; L535-Q540 HydrophobicContact CD2-CB 4.23Å; L535-Q540 PolarHBondContact O-N 3.31Å; L535-E543 HydrophobicContact CD1-CB 4.11Å; L535-A544 HydrophobicContact CB-CB 3.89Å; L535-Y547 HydrophobicContact CD1-CD2 3.44Å; L535-Y547 VanDerWaalsContact CD1-CD2 3.44Å; L535-Y547 HydrophobicContact CD1-CE2 3.75Å
536A97.6Very high96.9Very high0 Ų025.4 Ų25.40%014%0.143CC..Hα-helixtrans-62.3-45.5175.700000111.6A532 L533 Q534 S538 R539 A544 L564 L568 F847A532-A536 WeakPolarHBondContact O-CB 3.43Å; A532-A536 PolarHBondContact O-N 2.9Å; L533-A536 WeakPolarHBondContact O-CB 3.33Å; L533-A536 PolarHBondContact O-N 2.73Å; Q534-A536 VanDerWaalsContact C-N 3.34Å; A536-S538 VanDerWaalsContact C-N 3.26Å; A536-S538 PolarHBondContact O-N 3.07Å; A536-R539 WeakPolarHBondContact O-CA 3.2Å; A536-R539 PolarHBondContact O-N 3.37Å; A536-A544 HydrophobicContact CB-CB 4.11Å; A536-L564 HydrophobicContact CB-CD1 4.08Å; A536-L568 HydrophobicContact CB-CD2 3.79Å; A536-F847 VanDerWaalsContact C-CD2 3.48Å; A536-F847 HydrophobicContact CB-CB 4.44Å; A536-F847 HydrophobicContact CB-CD1 3.87Å; A536-F847 HydrophobicContact CB-CD2 3.85Å; A536-F847 HydrophobicContact CB-CE1 3.99Å; A536-F847 HydrophobicContact CB-CE2 3.97Å; A536-F847 HydrophobicContact CB-CG 3.79Å; A536-F847 HydrophobicContact CB-CZ 4.05Å; A536-F847 VanDerWaalsContact O-CD2 3.25Å; A536-F847 WeakPolarHBondContact O-CD2 3.33Å; A536-F847 WeakPolarHBondContact O-CE2 3.49Å
537V95.1Very high97.1Very high28 Ų2826.3 Ų26.317%0.1714%0.144CC..Hα-helixtrans-59.2-38.4174.11710000111.3L533 Q534 R539 F847 T848L533-V537 WeakPolarHBondContact O-CG2 3.35Å; L533-V537 PolarHBondContact O-N 2.88Å; Q534-V537 PolarHBondContact O-N 3.25Å; V537-R539 PolarHBondContact O-N 3.05Å; V537-F847 HydrophobicContact CG2-CB 4.11Å; V537-T848 HydrophobicContact CG2-CG2 4.1Å
538S94.6Very high97.2Very high35 Ų3526.3 Ų26.325%0.24514%0.143CC..THydrogen-bonded Turntrans-76.67173.8-56.10000114.4Q534 L535 A536 Q540Q534-S538 PolarHBondContact O-N 3.27Å; Q534-S538 PolarHBondContact O-OG 3.48Å; Q534-S538 VanDerWaalsContact O-OG 3.05Å; L535-S538 CarbonylContact O-C 3.51Å; L535-S538 PolarHBondContact O-N 3.27Å; A536-S538 VanDerWaalsContact C-N 3.26Å; A536-S538 PolarHBondContact O-N 3.07Å; S538-Q540 PolarHBondContact O-N 2.96Å
539R94.9Very high97.2Very high52 Ų5233.5 Ų33.520%0.19617%0.17CC..THydrogen-bonded Turntrans61.320.4-178.7-52.8-59.9-179.81403.4115.6L535 A536 V537 I541 T807 S841L535-R539 PolarHBondContact O-N 3.06Å; A536-R539 WeakPolarHBondContact O-CA 3.2Å; A536-R539 PolarHBondContact O-N 3.37Å; V537-R539 PolarHBondContact O-N 3.05Å; R539-I541 VanDerWaalsContact C-N 3.29Å; R539-I541 PolarHBondContact O-N 3.39Å; R539-I541 VanDerWaalsContact O-N 3.09Å; R539-T807 PolarHBondContact NH2-O 3.4Å; R539-T807 PolarHBondContact NH2-OG1 2.93Å; R539-S841 PolarHBondContact NH1-O 2.96Å
540Q96.2Very high97.2Very high73 Ų7336.4 Ų36.434%0.34118%0.184SC..  trans-87.667.8174.6-66.1174.316.500110.4L535 S538 E543 A544L535-Q540 HydrophobicContact CB-CB 4.44Å; L535-Q540 HydrophobicContact CD2-CB 4.23Å; L535-Q540 PolarHBondContact O-N 3.31Å; S538-Q540 PolarHBondContact O-N 2.96Å; Q540-E543 PolarHBondContact O-N 2.93Å; Q540-E543 PolarHBondContact OE1-OE2 3.11Å; Q540-A544 WeakPolarHBondContact O-CB 3.4Å; Q540-A544 PolarHBondContact O-N 3.42Å
541I97.1Very high97.1Very high12 Ų1235.8 Ų35.86%0.06218%0.181CC..Hα-helixtrans-58.3-45.5-169-49.3-55.9000113.9R539 E543 A544 L545 L568 A571 Q572 F847R539-I541 VanDerWaalsContact C-N 3.29Å; R539-I541 PolarHBondContact O-N 3.39Å; R539-I541 VanDerWaalsContact O-N 3.09Å; I541-E543 PolarHBondContact O-N 3.42Å; I541-A544 PolarHBondContact O-N 3.32Å; I541-L545 HydrophobicContact CG2-CD1 4.3Å; I541-L545 PolarHBondContact O-N 3.42Å; I541-L568 HydrophobicContact CD1-CD2 4.11Å; I541-L568 HydrophobicContact CG2-CD2 4.02Å; I541-A571 HydrophobicContact CD1-CB 4.11Å; I541-Q572 HydrophobicContact CG2-CG 3.84Å; I541-F847 HydrophobicContact CD1-CE2 4.22Å; I541-F847 HydrophobicContact CD1-CZ 3.96Å
542P96.4Very high97.1Very high96 Ų9637 Ų3762%0.62319%0.188SC*.Hα-helixtrans-65.8-40.5-177.4-22.235.1000113.3L545 G546P542-L545 PolarHBondContact O-N 3.17Å; P542-G546 PolarHBondContact O-N 2.72Å
543E96.8Very high97.1Very high108 Ų10845 Ų4551%0.50523%0.225SC..Hα-helixtrans-68.2-43.4178.4-63.9175.2-154.700110.6L535 Q540 I541 L545 G546 Y547L535-E543 HydrophobicContact CD1-CB 4.11Å; Q540-E543 PolarHBondContact O-N 2.93Å; Q540-E543 PolarHBondContact OE1-OE2 3.11Å; I541-E543 PolarHBondContact O-N 3.42Å; E543-L545 VanDerWaalsContact C-N 3.33Å; E543-L545 PolarHBondContact O-N 2.85Å; E543-G546 PolarHBondContact O-N 3.17Å; E543-G546 VanDerWaalsContact O-N 3.13Å; E543-Y547 WeakPolarHBondContact O-CD2 3.49Å; E543-Y547 PolarHBondContact O-N 2.96Å; E543-Y547 VanDerWaalsContact O-N 3.15Å
544A98.1Very high97Very high0 Ų047.5 Ų47.50%024%0.239CC..Hα-helixtrans-56.7-45.6174.100000111.6A532 L535 A536 Q540 I541 G546 Y547 V548 L568A532-A544 WeakPolarHBondContact O-CB 3.33Å; L535-A544 HydrophobicContact CB-CB 3.89Å; A536-A544 HydrophobicContact CB-CB 4.11Å; Q540-A544 WeakPolarHBondContact O-CB 3.4Å; Q540-A544 PolarHBondContact O-N 3.42Å; I541-A544 PolarHBondContact O-N 3.32Å; A544-G546 VanDerWaalsContact C-N 3.3Å; A544-G546 PolarHBondContact O-N 3.28Å; A544-Y547 PolarHBondContact O-N 3.42Å; A544-V548 WeakPolarHBondContact O-CG2 3.28Å; A544-V548 PolarHBondContact O-N 3.01Å; A544-L568 HydrophobicContact CB-CD1 3.91Å; A544-L568 HydrophobicContact CB-CD2 3.72Å
545L97.9Very high96.8Very high8 Ų852.4 Ų52.44%0.04226%0.261CS..Hα-helixtrans-59.8-38.1176.5-81.2170.5000113I541 P542 E543 R549 L565 L568I541-L545 HydrophobicContact CG2-CD1 4.3Å; I541-L545 PolarHBondContact O-N 3.42Å; P542-L545 PolarHBondContact O-N 3.17Å; E543-L545 VanDerWaalsContact C-N 3.33Å; E543-L545 PolarHBondContact O-N 2.85Å; L545-R549 WeakPolarHBondContact O-CB 3.2Å; L545-R549 VanDerWaalsContact O-CG 3.29Å; L545-R549 WeakPolarHBondContact O-CG 3.39Å; L545-R549 PolarHBondContact O-N 2.96Å; L545-R549 VanDerWaalsContact O-N 3.09Å; L545-L565 HydrophobicContact CD2-CD1 3.68Å; L545-L568 HydrophobicContact CD2-CB 3.58Å; L545-L568 HydrophobicContact CD2-CD1 3.94Å; L545-L568 HydrophobicContact CD2-CG 4.38Å; L545-L568 HydrophobicContact CG-CB 3.96Å; L545-L568 HydrophobicContact CG-CD1 4.1Å
546G97.3Very high96.6Very high41 Ų4154.4 Ų54.442%0.42328%0.282SS..Hα-helixtrans-59.4-50.2174.900000111.8P542 E543 A544 R549 Q550P542-G546 PolarHBondContact O-N 2.72Å; E543-G546 PolarHBondContact O-N 3.17Å; E543-G546 VanDerWaalsContact O-N 3.13Å; A544-G546 VanDerWaalsContact C-N 3.3Å; A544-G546 PolarHBondContact O-N 3.28Å; G546-R549 PolarHBondContact O-N 3.2Å; G546-Q550 PolarHBondContact O-N 2.83Å; G546-Q550 VanDerWaalsContact O-N 3.07Å
547Y98Very high96.3Very high74 Ų7459.7 Ų59.729%0.2931%0.31SS..Hα-helixtrans-72.4-34.1-179.3-74.2-69.1000113.8Q518 L531 L535 E543 A544 R549 Q550 A551Q518-Y547 HydrophobicContact CG-CE1 4.46Å; L531-Y547 HydrophobicContact CD2-CD1 3.85Å; L531-Y547 HydrophobicContact CD2-CD2 4.15Å; L531-Y547 HydrophobicContact CD2-CE1 3.58Å; L531-Y547 HydrophobicContact CD2-CE2 3.89Å; L531-Y547 HydrophobicContact CD2-CG 4.12Å; L531-Y547 HydrophobicContact CG-CD1 4.48Å; L531-Y547 HydrophobicContact CG-CD2 4.21Å; L531-Y547 HydrophobicContact CG-CE2 4.29Å; L531-Y547 HydrophobicContact CG-CG 4.3Å; L535-Y547 HydrophobicContact CD1-CD2 3.44Å; L535-Y547 VanDerWaalsContact CD1-CD2 3.44Å; L535-Y547 HydrophobicContact CD1-CE2 3.75Å; E543-Y547 WeakPolarHBondContact O-CD2 3.49Å; E543-Y547 PolarHBondContact O-N 2.96Å; E543-Y547 VanDerWaalsContact O-N 3.15Å; A544-Y547 PolarHBondContact O-N 3.42Å; Y547-R549 VanDerWaalsContact C-N 3.34Å; Y547-Q550 WeakPolarHBondContact O-CB 3.4Å; Y547-Q550 PolarHBondContact O-N 3.14Å; Y547-A551 PolarHBondContact O-N 2.8Å
548V98.1Very high96.3Very high0 Ų059.5 Ų59.50%031%0.309CS..Hα-helixtrans-62.8-42.5172.3174.30000111A532 A544 Q550 A551 L552 S561 L564 L565 L568A532-V548 HydrophobicContact CB-CB 4.4Å; A532-V548 HydrophobicContact CB-CG2 3.42Å; A532-V548 VanDerWaalsContact CB-CG2 3.42Å; A544-V548 WeakPolarHBondContact O-CG2 3.28Å; A544-V548 PolarHBondContact O-N 3.01Å; V548-Q550 VanDerWaalsContact C-N 3.28Å; V548-Q550 PolarHBondContact O-N 3.43Å; V548-A551 WeakPolarHBondContact O-CB 3.43Å; V548-A551 PolarHBondContact O-N 3.47Å; V548-L552 HydrophobicContact CG1-CD1 3.95Å; V548-L552 HydrophobicContact CG1-CG 4.37Å; V548-L552 WeakPolarHBondContact O-CG 3.32Å; V548-L552 PolarHBondContact O-N 3.15Å; V548-S561 WeakPolarHBondContact CG1-O 3.45Å; V548-L564 HydrophobicContact CG2-CB 4.28Å; V548-L564 HydrophobicContact CG2-CD2 3.45Å; V548-L564 VanDerWaalsContact CG2-CD2 3.45Å; V548-L564 HydrophobicContact CG2-CG 3.69Å; V548-L565 HydrophobicContact CG1-CB 3.81Å; V548-L565 HydrophobicContact CG1-CD1 4.47Å; V548-L568 HydrophobicContact CB-CD1 4.33Å; V548-L568 HydrophobicContact CG2-CD1 3.57Å
549R97.3Very high96.4Very high151 Ų15158.7 Ų58.757%0.5730%0.302SS*.Hα-helixtrans-63.2-37.2175.4-73.7174.2179.5158.60.8111.8L545 G546 Y547 L552 Q553L545-R549 WeakPolarHBondContact O-CB 3.2Å; L545-R549 VanDerWaalsContact O-CG 3.29Å; L545-R549 WeakPolarHBondContact O-CG 3.39Å; L545-R549 PolarHBondContact O-N 2.96Å; L545-R549 VanDerWaalsContact O-N 3.09Å; G546-R549 PolarHBondContact O-N 3.2Å; Y547-R549 VanDerWaalsContact C-N 3.34Å; R549-L552 PolarHBondContact O-N 3.38Å; R549-Q553 WeakPolarHBondContact O-CB 3.34Å; R549-Q553 PolarHBondContact O-N 3.44Å
550Q96.8Very high96.5Very high63 Ų6359 Ų5929%0.29431%0.305SS..Hα-helixtrans-63.3-44172.2-174.3177.99.400111.7G546 Y547 V548 L552 Q553 L554G546-Q550 PolarHBondContact O-N 2.83Å; G546-Q550 VanDerWaalsContact O-N 3.07Å; Y547-Q550 WeakPolarHBondContact O-CB 3.4Å; Y547-Q550 PolarHBondContact O-N 3.14Å; V548-Q550 VanDerWaalsContact C-N 3.28Å; V548-Q550 PolarHBondContact O-N 3.43Å; Q550-L552 PolarHBondContact O-N 3.1Å; Q550-Q553 WeakPolarHBondContact O-CB 3.4Å; Q550-Q553 PolarHBondContact O-N 3.18Å; Q550-L554 WeakPolarHBondContact O-CG 3.36Å; Q550-L554 PolarHBondContact O-N 2.92Å; Q550-L554 VanDerWaalsContact O-N 3.14Å
551A97.4Very high96.5Very high0 Ų055.5 Ų55.50%029%0.289CS..Hα-helixtrans-60.4-44.6176.100000111.6A528 F529 Y547 V548 Q553 L554 Q555A528-A551 HydrophobicContact CB-CB 3.97Å; F529-A551 HydrophobicContact CB-CB 4.11Å; Y547-A551 PolarHBondContact O-N 2.8Å; V548-A551 WeakPolarHBondContact O-CB 3.43Å; V548-A551 PolarHBondContact O-N 3.47Å; A551-Q553 VanDerWaalsContact C-N 3.32Å; A551-Q553 PolarHBondContact O-N 3.09Å; A551-L554 WeakPolarHBondContact O-CB 3.43Å; A551-L554 PolarHBondContact O-N 3.15Å; A551-L554 VanDerWaalsContact O-N 3.14Å; A551-Q555 PolarHBondContact O-N 3.06Å
552L97Very high96.6Very high26 Ų2655.3 Ų55.314%0.13629%0.288CS..Hα-helixtrans-67.2-29.8175.5-70.3170000113.2V548 R549 Q550 L554 Q555 G556 L562 L565V548-L552 HydrophobicContact CG1-CD1 3.95Å; V548-L552 HydrophobicContact CG1-CG 4.37Å; V548-L552 WeakPolarHBondContact O-CG 3.32Å; V548-L552 PolarHBondContact O-N 3.15Å; R549-L552 PolarHBondContact O-N 3.38Å; Q550-L552 PolarHBondContact O-N 3.1Å; L552-L554 VanDerWaalsContact C-N 3.27Å; L552-L554 PolarHBondContact O-N 2.89Å; L552-Q555 WeakPolarHBondContact CA-O 3.42Å; L552-Q555 CarbonylContact O-C 3.39Å; L552-G556 WeakPolarHBondContact O-CA 3.39Å; L552-G556 PolarHBondContact O-N 3.03Å; L552-G556 VanDerWaalsContact O-N 3.07Å; L552-L562 HydrophobicContact CD1-CD2 4.24Å; L552-L562 HydrophobicContact CD2-CD2 3.67Å; L552-L562 HydrophobicContact CD2-CG 3.86Å; L552-L565 HydrophobicContact CD1-CB 4.27Å; L552-L565 HydrophobicContact CD1-CD2 3.67Å
553Q97.3Very high96.7Very high168 Ų16851 Ų5179%0.78526%0.26SS*.Hα-helixtrans-67.5-31.6173-172.317712.600111.7R549 Q550 A551R549-Q553 WeakPolarHBondContact O-CB 3.34Å; R549-Q553 PolarHBondContact O-N 3.44Å; Q550-Q553 WeakPolarHBondContact O-CB 3.4Å; Q550-Q553 PolarHBondContact O-N 3.18Å; A551-Q553 VanDerWaalsContact C-N 3.32Å; A551-Q553 PolarHBondContact O-N 3.09Å
554L96.1Very high96.7Very high59 Ų5945.8 Ų45.831%0.30924%0.236SC..Hα-helixtrans-80.2-39.8175.5-64.3168.9000111.9H525 Q550 A551 L552H525-L554 HydrophobicContact CB-CB 3.84Å; H525-L554 HydrophobicContact CB-CD1 4.23Å; Q550-L554 WeakPolarHBondContact O-CG 3.36Å; Q550-L554 PolarHBondContact O-N 2.92Å; Q550-L554 VanDerWaalsContact O-N 3.14Å; A551-L554 WeakPolarHBondContact O-CB 3.43Å; A551-L554 PolarHBondContact O-N 3.15Å; A551-L554 VanDerWaalsContact O-N 3.14Å; L552-L554 VanDerWaalsContact C-N 3.27Å; L552-L554 PolarHBondContact O-N 2.89Å
555Q95.8Very high96.8Very high106 Ų10646.7 Ų46.750%0.49524%0.24SC..  trans-140.696.8178.2-69.1-64-64.500110.1H525 A551 L552 D557 D558H525-Q555 HydrophobicContact CB-CB 4.19Å; H525-Q555 HydrophobicContact CB-CG 3.84Å; A551-Q555 PolarHBondContact O-N 3.06Å; L552-Q555 WeakPolarHBondContact CA-O 3.42Å; L552-Q555 CarbonylContact O-C 3.39Å; Q555-D557 VanDerWaalsContact C-N 3.31Å; Q555-D557 PolarHBondContact O-N 2.9Å; Q555-D558 HydrophobicContact CB-CB 4.2Å
556G93.4Very high96.8Very high43 Ų4346.3 Ų46.344%0.44324%0.238SC..THydrogen-bonded Turntrans-65.6-31.1-174.600000114.5L552L552-G556 WeakPolarHBondContact O-CA 3.39Å; L552-G556 PolarHBondContact O-N 3.03Å; L552-G556 VanDerWaalsContact O-N 3.07Å
557D91.5Very high96.8Very high110 Ų11044.3 Ų44.359%0.58822%0.218SC*.THydrogen-bonded Turntrans-99.111.5-171.9-51.4-29.2000112.4Q555 V559 Y589Q555-D557 VanDerWaalsContact C-N 3.31Å; Q555-D557 PolarHBondContact O-N 2.9Å; D557-V559 PolarHBondContact O-N 2.86Å; D557-Y589 WeakPolarHBondContact O-CE2 3.41Å; D557-Y589 PolarHBondContact O-OH 3.48Å
558D95.2Very high96.8Very high25 Ų2540.8 Ų40.813%0.13420%0.204CC..  trans-68.4116.7-179.7176.249.4000111.7Q555 H560 S561 L562Q555-D558 HydrophobicContact CB-CB 4.2Å; D558-H560 VanDerWaalsContact C-N 3.27Å; D558-H560 PolarHBondContact O-N 3.12Å; D558-S561 PolarHBondContact O-N 2.98Å; D558-S561 WeakPolarHBondContact OD2-CB 3.46Å; D558-S561 PolarHBondContact OD2-N 3.46Å; D558-S561 PolarHBondContact OD2-OG 3.32Å; D558-L562 WeakPolarHBondContact O-CG 3.43Å; D558-L562 PolarHBondContact O-N 3.42Å
559V95.9Very high96.8Very high18 Ų1841.7 Ų41.711%0.10921%0.209CC..Hα-helixtrans-57.7-38.9-175.969.20000112.5D557 H563 Y589 N592 L595D557-V559 PolarHBondContact O-N 2.86Å; V559-H563 VanDerWaalsContact O-CB 3.3Å; V559-H563 WeakPolarHBondContact O-CB 3.31Å; V559-H563 PolarHBondContact O-N 2.79Å; V559-Y589 HydrophobicContact CB-CD2 3.9Å; V559-Y589 HydrophobicContact CB-CE1 4.36Å; V559-Y589 HydrophobicContact CB-CE2 3.74Å; V559-Y589 HydrophobicContact CB-CG 4.29Å; V559-Y589 HydrophobicContact CG2-CD1 4.48Å; V559-Y589 HydrophobicContact CG2-CD2 3.78Å; V559-Y589 HydrophobicContact CG2-CE2 4.17Å; V559-Y589 HydrophobicContact CG2-CG 3.96Å; V559-N592 WeakPolarHBondContact CG2-ND2 3.42Å; V559-L595 HydrophobicContact CG2-CD1 3.84Å; V559-L595 HydrophobicContact CG2-CG 4.32Å
560H96.8Very high96.8Very high57 Ų5734.5 Ų34.526%0.26418%0.182SC..Hα-helixtrans-76.3-39.3-176.8-65.6-46000111.9F529 D558 H563 L564 I850F529-H560 HydrophobicContact CE1-CB 4.13Å; F529-H560 HydrophobicContact CE2-CB 3.83Å; F529-H560 WeakPolarHBondContact CE2-O 3.31Å; F529-H560 HydrophobicContact CZ-CB 3.64Å; D558-H560 VanDerWaalsContact C-N 3.27Å; D558-H560 PolarHBondContact O-N 3.12Å; H560-H563 PolarHBondContact O-N 3.14Å; H560-L564 WeakPolarHBondContact O-CB 3.19Å; H560-L564 PolarHBondContact O-N 3.43Å; H560-I850 HydrophobicContact CB-CG2 3.93Å
561S97.4Very high96.8Very high0 Ų031.6 Ų31.60%017%0.168CC..Hα-helixtrans-65.8-41.5174.7-62.70000112.2F529 V548 D558 L564 L565F529-S561 WeakPolarHBondContact CD2-OG 3.23Å; V548-S561 WeakPolarHBondContact CG1-O 3.45Å; D558-S561 PolarHBondContact O-N 2.98Å; D558-S561 WeakPolarHBondContact OD2-CB 3.46Å; D558-S561 PolarHBondContact OD2-N 3.46Å; D558-S561 PolarHBondContact OD2-OG 3.32Å; S561-L564 PolarHBondContact O-N 2.9Å; S561-L565 WeakPolarHBondContact O-CB 3.4Å; S561-L565 PolarHBondContact O-N 3.44Å
562L97.8Very high96.8Very high9 Ų935 Ų355%0.04718%0.184CC..Hα-helixtrans-63.5-43.4173.7-70.3175.6000111.6L552 D558 L564 L565 A566 I581 M584 A585L552-L562 HydrophobicContact CD1-CD2 4.24Å; L552-L562 HydrophobicContact CD2-CD2 3.67Å; L552-L562 HydrophobicContact CD2-CG 3.86Å; D558-L562 WeakPolarHBondContact O-CG 3.43Å; D558-L562 PolarHBondContact O-N 3.42Å; L562-L564 PolarHBondContact O-N 2.99Å; L562-L565 WeakPolarHBondContact O-CB 3.26Å; L562-L565 PolarHBondContact O-N 3.43Å; L562-A566 PolarHBondContact O-N 3.46Å; L562-I581 HydrophobicContact CB-CG2 4.48Å; L562-I581 HydrophobicContact CD2-CG2 4.36Å; L562-I581 WeakPolarHBondContact O-CG2 3.49Å; L562-M584 HydrophobicContact CD1-CE 4.32Å; L562-M584 HydrophobicContact CD2-CE 3.46Å; L562-M584 VanDerWaalsContact CD2-CE 3.46Å; L562-A585 HydrophobicContact CB-CB 4.04Å; L562-A585 HydrophobicContact CD1-CB 3.94Å
563H98.3Very high96.8Very high4 Ų437.1 Ų37.12%0.01919%0.192CC..Hα-helixtrans-60.6-46.6175.9-167179.9000111.4V559 H560 L565 A566 L567 L595 T598 I850V559-H563 VanDerWaalsContact O-CB 3.3Å; V559-H563 WeakPolarHBondContact O-CB 3.31Å; V559-H563 PolarHBondContact O-N 2.79Å; H560-H563 PolarHBondContact O-N 3.14Å; H563-L565 VanDerWaalsContact C-N 3.34Å; H563-L565 PolarHBondContact O-N 3.22Å; H563-A566 PolarHBondContact O-N 2.98Å; H563-L567 WeakPolarHBondContact O-CG 3.14Å; H563-L567 PolarHBondContact O-N 3.35Å; H563-L595 HydrophobicContact CB-CD2 3.67Å; H563-T598 PolarHBondContact CE1-OG1 3.38Å; H563-T598 PolarHBondContact NE2-OG1 2.86Å; H563-I850 HydrophobicContact CB-CD1 4.1Å; H563-I850 HydrophobicContact CB-CG1 4.47Å
564L98.3Very high96.8Very high0 Ų033.6 Ų33.60%018%0.176CC..Hα-helixtrans-64.7-38178.6-175.557.7000112F529 A532 L533 A536 V548 H560 S561 L562 A566 L567 L568 F847 I850F529-L564 HydrophobicContact CD2-CD2 4.12Å; F529-L564 HydrophobicContact CE2-CB 3.99Å; F529-L564 HydrophobicContact CE2-CD2 3.75Å; A532-L564 HydrophobicContact CB-CD2 4.07Å; L533-L564 HydrophobicContact CB-CD2 3.92Å; L533-L564 HydrophobicContact CD1-CD1 3.79Å; L533-L564 HydrophobicContact CD1-CD2 4.19Å; A536-L564 HydrophobicContact CB-CD1 4.08Å; V548-L564 HydrophobicContact CG2-CB 4.28Å; V548-L564 HydrophobicContact CG2-CD2 3.45Å; V548-L564 VanDerWaalsContact CG2-CD2 3.45Å; V548-L564 HydrophobicContact CG2-CG 3.69Å; H560-L564 WeakPolarHBondContact O-CB 3.19Å; H560-L564 PolarHBondContact O-N 3.43Å; S561-L564 PolarHBondContact O-N 2.9Å; L562-L564 PolarHBondContact O-N 2.99Å; L564-A566 PolarHBondContact O-N 3.06Å; L564-L567 PolarHBondContact O-N 3.49Å; L564-L568 HydrophobicContact CD1-CD1 4.42Å; L564-L568 HydrophobicContact CD1-CG 4.29Å; L564-L568 HydrophobicContact CG-CD1 4.05Å; L564-L568 HydrophobicContact CG-CG 4.4Å; L564-L568 WeakPolarHBondContact O-CB 3.35Å; L564-L568 VanDerWaalsContact O-CG 3.29Å; L564-L568 WeakPolarHBondContact O-CG 3.24Å; L564-L568 PolarHBondContact O-N 2.93Å; L564-F847 HydrophobicContact CD1-CD1 3.75Å; L564-F847 HydrophobicContact CD1-CE1 4.32Å; L564-I850 HydrophobicContact CB-CD1 3.67Å; L564-I850 HydrophobicContact CD1-CD1 4.21Å; L564-I850 HydrophobicContact CG-CD1 4.47Å
565L98.3Very high96.8Very high18 Ų1833.5 Ų33.59%0.09417%0.171CC..Hα-helixtrans-58.5-48.1173.8179.559.4000111L545 V548 L552 S561 L562 H563 L567 L568 L569 I581L545-L565 HydrophobicContact CD2-CD1 3.68Å; V548-L565 HydrophobicContact CG1-CB 3.81Å; V548-L565 HydrophobicContact CG1-CD1 4.47Å; L552-L565 HydrophobicContact CD1-CB 4.27Å; L552-L565 HydrophobicContact CD1-CD2 3.67Å; S561-L565 WeakPolarHBondContact O-CB 3.4Å; S561-L565 PolarHBondContact O-N 3.44Å; L562-L565 WeakPolarHBondContact O-CB 3.26Å; L562-L565 PolarHBondContact O-N 3.43Å; H563-L565 VanDerWaalsContact C-N 3.34Å; H563-L565 PolarHBondContact O-N 3.22Å; L565-L567 VanDerWaalsContact C-N 3.34Å; L565-L567 PolarHBondContact O-N 3.4Å; L565-L568 PolarHBondContact O-N 3.45Å; L565-L569 HydrophobicContact CD1-CD1 4.3Å; L565-L569 HydrophobicContact CD1-CG 4.3Å; L565-L569 HydrophobicContact CG-CD1 4.16Å; L565-L569 WeakPolarHBondContact O-CG 3.35Å; L565-L569 PolarHBondContact O-N 3.41Å; L565-I581 HydrophobicContact CD2-CD1 4.07Å; L565-I581 HydrophobicContact CD2-CG1 4.26Å; L565-I581 HydrophobicContact CD2-CG2 4.31Å; L565-I581 HydrophobicContact CG-CG2 4.48Å
566A98.1Very high96.9Very high0 Ų033.7 Ų33.70%017%0.172CC..Hα-helixtrans-61.2-4217700000112.2L562 H563 L564 L569 S570 A578 I581 I582L562-A566 PolarHBondContact O-N 3.46Å; H563-A566 PolarHBondContact O-N 2.98Å; L564-A566 PolarHBondContact O-N 3.06Å; A566-L569 PolarHBondContact O-N 3.45Å; A566-S570 WeakPolarHBondContact O-CB 3.49Å; A566-S570 PolarHBondContact O-N 3.49Å; A566-A578 HydrophobicContact CB-CB 4.41Å; A566-A578 VanDerWaalsContact O-CB 3.31Å; A566-A578 WeakPolarHBondContact O-CB 3.48Å; A566-I581 HydrophobicContact CB-CB 4.31Å; A566-I581 HydrophobicContact CB-CG2 4.11Å; A566-I582 HydrophobicContact CB-CD1 3.6Å; A566-I582 HydrophobicContact CB-CG1 3.58Å
567L98.4Very high97.1Very high0 Ų035.7 Ų35.70%017%0.173CC..Hα-helixtrans-64.2-40.7176.5-66.3177.4000111.9H563 L564 L565 S570 A571 T598 I844 L845 F847 I849 I850H563-L567 WeakPolarHBondContact O-CG 3.14Å; H563-L567 PolarHBondContact O-N 3.35Å; L564-L567 PolarHBondContact O-N 3.49Å; L565-L567 VanDerWaalsContact C-N 3.34Å; L565-L567 PolarHBondContact O-N 3.4Å; L567-S570 PolarHBondContact O-N 3.15Å; L567-S570 PolarHBondContact O-OG 2.96Å; L567-A571 PolarHBondContact O-N 3.24Å; L567-T598 HydrophobicContact CD2-CG2 3.87Å; L567-I844 HydrophobicContact CD2-CG2 4.09Å; L567-L845 HydrophobicContact CD2-CB 4.03Å; L567-F847 HydrophobicContact CB-CD1 3.82Å; L567-F847 HydrophobicContact CB-CE1 3.76Å; L567-F847 HydrophobicContact CD1-CD1 4.24Å; L567-I849 HydrophobicContact CD1-CG2 3.8Å; L567-I850 HydrophobicContact CD1-CD1 4.11Å; L567-I850 HydrophobicContact CD1-CG1 4.41Å
568L98.4Very high97.4Very high0 Ų030.5 Ų30.50%015%0.145CC..Hα-helixtrans-66.6-41.2176.8-72.8168.2000112.3A536 I541 A544 L545 V548 L564 L565 S570 A571 Q572 F847A536-L568 HydrophobicContact CB-CD2 3.79Å; I541-L568 HydrophobicContact CD1-CD2 4.11Å; I541-L568 HydrophobicContact CG2-CD2 4.02Å; A544-L568 HydrophobicContact CB-CD1 3.91Å; A544-L568 HydrophobicContact CB-CD2 3.72Å; L545-L568 HydrophobicContact CD2-CB 3.58Å; L545-L568 HydrophobicContact CD2-CD1 3.94Å; L545-L568 HydrophobicContact CD2-CG 4.38Å; L545-L568 HydrophobicContact CG-CB 3.96Å; L545-L568 HydrophobicContact CG-CD1 4.1Å; V548-L568 HydrophobicContact CB-CD1 4.33Å; V548-L568 HydrophobicContact CG2-CD1 3.57Å; L564-L568 HydrophobicContact CD1-CD1 4.42Å; L564-L568 HydrophobicContact CD1-CG 4.29Å; L564-L568 HydrophobicContact CG-CD1 4.05Å; L564-L568 HydrophobicContact CG-CG 4.4Å; L564-L568 WeakPolarHBondContact O-CB 3.35Å; L564-L568 VanDerWaalsContact O-CG 3.29Å; L564-L568 WeakPolarHBondContact O-CG 3.24Å; L564-L568 PolarHBondContact O-N 2.93Å; L565-L568 PolarHBondContact O-N 3.45Å; L568-S570 VanDerWaalsContact C-N 3.32Å; L568-A571 WeakPolarHBondContact O-CB 3.4Å; L568-A571 PolarHBondContact O-N 2.91Å; L568-Q572 PolarHBondContact O-N 3.45Å; L568-Q572 VanDerWaalsContact O-N 3.17Å; L568-F847 HydrophobicContact CD2-CE1 3.89Å; L568-F847 HydrophobicContact CD2-CZ 3.97Å; L568-F847 HydrophobicContact CG-CE1 4.16Å
569L97.9Very high97.5Very high19 Ų1929.3 Ų29.310%0.09914%0.139CC..Hα-helixtrans-63.1-40.4173.2-70.3172.9000111.3L565 A566 A571 Q572 K573 H574 D577 A578 I581L565-L569 HydrophobicContact CD1-CD1 4.3Å; L565-L569 HydrophobicContact CD1-CG 4.3Å; L565-L569 HydrophobicContact CG-CD1 4.16Å; L565-L569 WeakPolarHBondContact O-CG 3.35Å; L565-L569 PolarHBondContact O-N 3.41Å; A566-L569 PolarHBondContact O-N 3.45Å; L569-A571 VanDerWaalsContact C-N 3.28Å; L569-A571 PolarHBondContact O-N 3.15Å; L569-Q572 CarbonylContact O-C 3.36Å; L569-Q572 PolarHBondContact O-N 3.11Å; L569-Q572 VanDerWaalsContact O-N 3.12Å; L569-K573 PolarHBondContact O-N 3.15Å; L569-H574 HydrophobicContact CB-CB 4.44Å; L569-H574 PolarHBondContact O-N 3.04Å; L569-D577 HydrophobicContact CD1-CB 4.13Å; L569-A578 HydrophobicContact CB-CB 3.97Å; L569-I581 HydrophobicContact CD1-CG1 4.05Å
570S97.8Very high97.5Very high0 Ų032.5 Ų32.50%016%0.155CC..Hα-helixtrans-63.8-33.8174.183.40000112.4A566 L567 L568 Q572 K573 I844A566-S570 WeakPolarHBondContact O-CB 3.49Å; A566-S570 PolarHBondContact O-N 3.49Å; L567-S570 PolarHBondContact O-N 3.15Å; L567-S570 PolarHBondContact O-OG 2.96Å; L568-S570 VanDerWaalsContact C-N 3.32Å; S570-Q572 VanDerWaalsContact C-N 3.26Å; S570-Q572 PolarHBondContact O-N 3.1Å; S570-K573 WeakPolarHBondContact O-CA 3.16Å; S570-K573 PolarHBondContact O-N 2.81Å; S570-I844 PolarHBondContact OG-N 2.71Å
571A96.9Very high97.6Very high1 Ų131.4 Ų31.41%0.00815%0.151CC..Hα-helixtrans-66.4-30.2174.800000112.3I541 L567 L568 L569 K573 S842 P843 F847I541-A571 HydrophobicContact CD1-CB 4.11Å; L567-A571 PolarHBondContact O-N 3.24Å; L568-A571 WeakPolarHBondContact O-CB 3.4Å; L568-A571 PolarHBondContact O-N 2.91Å; L569-A571 VanDerWaalsContact C-N 3.28Å; L569-A571 PolarHBondContact O-N 3.15Å; A571-K573 PolarHBondContact O-N 3.35Å; A571-S842 WeakPolarHBondContact CA-O 3.34Å; A571-P843 HydrophobicContact CB-CB 4.09Å; A571-F847 HydrophobicContact CB-CZ 4.11Å
572Q96.7Very high97.6Very high72 Ų7231.4 Ų31.434%0.33615%0.151SC..THydrogen-bonded Turntrans-82.25.7170.4-63.1-175.1-29.900113.4I541 L568 L569 S570 H574I541-Q572 HydrophobicContact CG2-CG 3.84Å; L568-Q572 PolarHBondContact O-N 3.45Å; L568-Q572 VanDerWaalsContact O-N 3.17Å; L569-Q572 CarbonylContact O-C 3.36Å; L569-Q572 PolarHBondContact O-N 3.11Å; L569-Q572 VanDerWaalsContact O-N 3.12Å; S570-Q572 VanDerWaalsContact C-N 3.26Å; S570-Q572 PolarHBondContact O-N 3.1Å; Q572-H574 PolarHBondContact O-N 3.44Å
573K96.1Very high97.5Very high71 Ų7134.6 Ų34.631%0.30917%0.166SC..THydrogen-bonded Turntrans63.616.8-176-44.5-57.7-177-1720114.3L569 S570 A571 Y575 E839 S842L569-K573 PolarHBondContact O-N 3.15Å; S570-K573 WeakPolarHBondContact O-CA 3.16Å; S570-K573 PolarHBondContact O-N 2.81Å; A571-K573 PolarHBondContact O-N 3.35Å; K573-Y575 VanDerWaalsContact C-N 3.25Å; K573-Y575 HydrophobicContact CB-CE2 4.42Å; K573-Y575 HydrophobicContact CD-CE1 4.48Å; K573-Y575 VanDerWaalsContact CD-OH 3.3Å; K573-Y575 WeakPolarHBondContact CD-OH 3.24Å; K573-Y575 PolarHBondContact O-N 2.87Å; K573-E839 WeakPolarHBondContact CE-O 3.31Å; K573-E839 PolarHBondContact NZ-O 2.85Å; K573-E839 VanDerWaalsContact NZ-O 3.07Å; K573-E839 IonicContact NZ-OE1 2.67Å; K573-E839 PolarHBondContact NZ-OE1 2.86Å; K573-E839 IonicContact NZ-OE2 3.48Å; K573-S842 PolarHBondContact NZ-O 3.09Å; K573-S842 VanDerWaalsContact NZ-O 3.17Å
574H97.1Very high97.4Very high93 Ų9338.8 Ų38.843%0.43119%0.186SC..  trans-82.966.1171.8-60.7152.6000110.7L569 Q572 H576 D577 A578L569-H574 HydrophobicContact CB-CB 4.44Å; L569-H574 PolarHBondContact O-N 3.04Å; Q572-H574 PolarHBondContact O-N 3.44Å; H574-H576 PolarHBondContact O-N 3.25Å; H574-D577 HydrophobicContact CB-CB 4.38Å; H574-D577 PolarHBondContact O-N 2.94Å; H574-A578 WeakPolarHBondContact O-CB 3.42Å; H574-A578 PolarHBondContact O-N 3.45Å
575Y97.3Very high97.3Very high57 Ų5738.8 Ų38.822%0.22419%0.186CC..Hα-helixtrans-66.9-33.8-171.9-59.9-52.1000114.3K573 L579 L602 I844K573-Y575 VanDerWaalsContact C-N 3.25Å; K573-Y575 HydrophobicContact CB-CE2 4.42Å; K573-Y575 HydrophobicContact CD-CE1 4.48Å; K573-Y575 VanDerWaalsContact CD-OH 3.3Å; K573-Y575 WeakPolarHBondContact CD-OH 3.24Å; K573-Y575 PolarHBondContact O-N 2.87Å; Y575-L579 WeakPolarHBondContact O-CB 3.41Å; Y575-L579 PolarHBondContact O-N 3.47Å; Y575-L602 HydrophobicContact CD1-CD2 3.94Å; Y575-I844 HydrophobicContact CE1-CD1 4.5Å
576H96.8Very high97.2Very high111 Ų11138.7 Ų38.751%0.51419%0.186SC..Hα-helixtrans-67.9-44.5177.7-67.7-59.6000111.8H574 L579 N580H574-H576 PolarHBondContact O-N 3.25Å; H576-L579 PolarHBondContact O-N 3.37Å; H576-N580 VanDerWaalsContact O-CG 3.24Å; H576-N580 PolarHBondContact O-N 2.94Å; H576-N580 PolarHBondContact O-ND2 3.41Å
577D97.2Very high97.1Very high85 Ų8542.5 Ų42.546%0.45521%0.212SC..Hα-helixtrans-65.5-41.6176.5-62.2-29000111.1L569 H574 L579 N580 I581L569-D577 HydrophobicContact CD1-CB 4.13Å; H574-D577 HydrophobicContact CB-CB 4.38Å; H574-D577 PolarHBondContact O-N 2.94Å; D577-L579 VanDerWaalsContact C-N 3.32Å; D577-L579 PolarHBondContact O-N 3.31Å; D577-N580 PolarHBondContact O-N 3.04Å; D577-I581 WeakPolarHBondContact O-CG1 3.48Å; D577-I581 PolarHBondContact O-N 2.93Å
578A97.9Very high96.9Very high0 Ų048.4 Ų48.40%024%0.24CC..Hα-helixtrans-58.6-43.317400000112A566 L569 H574 I581 I582 L602A566-A578 HydrophobicContact CB-CB 4.41Å; A566-A578 VanDerWaalsContact O-CB 3.31Å; A566-A578 WeakPolarHBondContact O-CB 3.48Å; L569-A578 HydrophobicContact CB-CB 3.97Å; H574-A578 WeakPolarHBondContact O-CB 3.42Å; H574-A578 PolarHBondContact O-N 3.45Å; A578-I581 PolarHBondContact O-N 3.39Å; A578-I582 WeakPolarHBondContact O-CG1 3.23Å; A578-I582 PolarHBondContact O-N 2.88Å; A578-L602 HydrophobicContact CB-CD1 4.01Å; A578-L602 HydrophobicContact CB-CD2 4.02Å
579L97.8Very high96.7Very high1 Ų152.4 Ų52.41%0.00526%0.256CS..Hα-helixtrans-64.8-42.8177.9-177.562000111.5Y575 H576 D577 I581 I582 E583 K599 L602 E603 R607Y575-L579 WeakPolarHBondContact O-CB 3.41Å; Y575-L579 PolarHBondContact O-N 3.47Å; H576-L579 PolarHBondContact O-N 3.37Å; D577-L579 VanDerWaalsContact C-N 3.32Å; D577-L579 PolarHBondContact O-N 3.31Å; L579-I581 VanDerWaalsContact C-N 3.31Å; L579-I581 PolarHBondContact O-N 3.07Å; L579-I582 PolarHBondContact O-N 2.88Å; L579-I582 VanDerWaalsContact O-N 3.12Å; L579-E583 HydrophobicContact CD1-CG 4.42Å; L579-E583 HydrophobicContact CG-CG 4.47Å; L579-E583 WeakPolarHBondContact O-CG 3.43Å; L579-E583 PolarHBondContact O-N 3.42Å; L579-K599 HydrophobicContact CD1-CG 4.05Å; L579-L602 HydrophobicContact CB-CB 4.46Å; L579-L602 HydrophobicContact CD1-CB 4.15Å; L579-E603 HydrophobicContact CD1-CG 4.05Å; L579-E603 HydrophobicContact CD2-CG 4.36Å; L579-R607 HydrophobicContact CD2-CG 4.07Å
580N97.4Very high96.4Very high85 Ų8554.5 Ų54.546%0.45527%0.27SS..Hα-helixtrans-59.4-41.4176.2-66.7-23.1000111.8H576 D577 E583 M584H576-N580 VanDerWaalsContact O-CG 3.24Å; H576-N580 PolarHBondContact O-N 2.94Å; H576-N580 PolarHBondContact O-ND2 3.41Å; D577-N580 PolarHBondContact O-N 3.04Å; N580-E583 PolarHBondContact O-N 3.05Å; N580-M584 WeakPolarHBondContact O-CB 3.33Å; N580-M584 PolarHBondContact O-N 3.39Å
581I97.4Very high96Very high34 Ų3459.6 Ų59.617%0.17429%0.294CS..Hα-helixtrans-64.9-40.4175.6-64.1-61.6000111.2L562 L565 A566 L569 D577 A578 L579 M584 A585L562-I581 HydrophobicContact CB-CG2 4.48Å; L562-I581 HydrophobicContact CD2-CG2 4.36Å; L562-I581 WeakPolarHBondContact O-CG2 3.49Å; L565-I581 HydrophobicContact CD2-CD1 4.07Å; L565-I581 HydrophobicContact CD2-CG1 4.26Å; L565-I581 HydrophobicContact CD2-CG2 4.31Å; L565-I581 HydrophobicContact CG-CG2 4.48Å; A566-I581 HydrophobicContact CB-CB 4.31Å; A566-I581 HydrophobicContact CB-CG2 4.11Å; L569-I581 HydrophobicContact CD1-CG1 4.05Å; D577-I581 WeakPolarHBondContact O-CG1 3.48Å; D577-I581 PolarHBondContact O-N 2.93Å; A578-I581 PolarHBondContact O-N 3.39Å; L579-I581 VanDerWaalsContact C-N 3.31Å; L579-I581 PolarHBondContact O-N 3.07Å; I581-M584 HydrophobicContact CD1-CE 4.08Å; I581-M584 PolarHBondContact O-N 3.17Å; I581-A585 WeakPolarHBondContact O-CB 3.48Å; I581-A585 PolarHBondContact O-N 2.93Å
582I97.8Very high95.8Very high0 Ų061.5 Ų61.50%030%0.304CS..Hα-helixtrans-66.2-40.7176.1-69.5-65.5000111.6A566 A578 L579 M584 A585 L586 L595 T598 K599 L602A566-I582 HydrophobicContact CB-CD1 3.6Å; A566-I582 HydrophobicContact CB-CG1 3.58Å; A578-I582 WeakPolarHBondContact O-CG1 3.23Å; A578-I582 PolarHBondContact O-N 2.88Å; L579-I582 PolarHBondContact O-N 2.88Å; L579-I582 VanDerWaalsContact O-N 3.12Å; I582-M584 VanDerWaalsContact C-N 3.35Å; I582-A585 PolarHBondContact O-N 3.32Å; I582-L586 HydrophobicContact CG2-CD1 3.73Å; I582-L586 HydrophobicContact CG2-CG 4.32Å; I582-L586 WeakPolarHBondContact O-CB 3.15Å; I582-L586 VanDerWaalsContact O-CG 3.26Å; I582-L586 WeakPolarHBondContact O-CG 3.39Å; I582-L586 PolarHBondContact O-N 3Å; I582-L595 HydrophobicContact CD1-CD2 3.83Å; I582-T598 HydrophobicContact CD1-CG2 4.03Å; I582-T598 HydrophobicContact CG1-CG2 4.29Å; I582-K599 HydrophobicContact CG2-CB 3.71Å; I582-K599 HydrophobicContact CG2-CG 4.3Å; I582-L602 HydrophobicContact CG1-CD1 3.88Å
583E96.4Very high95.6Very high76 Ų7659.3 Ų59.336%0.35529%0.294SS..Hα-helixtrans-63.5-40.5175.8-72.8177.2168.800111.8L579 N580 L586 S587L579-E583 HydrophobicContact CD1-CG 4.42Å; L579-E583 HydrophobicContact CG-CG 4.47Å; L579-E583 WeakPolarHBondContact O-CG 3.43Å; L579-E583 PolarHBondContact O-N 3.42Å; N580-E583 PolarHBondContact O-N 3.05Å; E583-L586 PolarHBondContact O-N 2.97Å; E583-S587 PolarHBondContact O-N 2.67Å
584M95.8Very high95.5Very high91 Ų9158.4 Ų58.445%0.44829%0.292SS..Hα-helixtrans-64.5-43.5172.1-176.8-172.472.200111.8L562 N580 I581 I582 L586 S587L562-M584 HydrophobicContact CD1-CE 4.32Å; L562-M584 HydrophobicContact CD2-CE 3.46Å; L562-M584 VanDerWaalsContact CD2-CE 3.46Å; N580-M584 WeakPolarHBondContact O-CB 3.33Å; N580-M584 PolarHBondContact O-N 3.39Å; I581-M584 HydrophobicContact CD1-CE 4.08Å; I581-M584 PolarHBondContact O-N 3.17Å; I582-M584 VanDerWaalsContact C-N 3.35Å; M584-L586 VanDerWaalsContact C-N 3.28Å; M584-L586 PolarHBondContact O-N 3.23Å; M584-S587 PolarHBondContact O-N 3.37Å; M584-S587 PolarHBondContact O-OG 3.25Å
585A96.6Very high95.4Very high0 Ų054 Ų540%027%0.272CS..Hα-helixtrans-64.1-35.7176.200000111.7L562 I581 I582 S587 E588 Y589 L595L562-A585 HydrophobicContact CB-CB 4.04Å; L562-A585 HydrophobicContact CD1-CB 3.94Å; I581-A585 WeakPolarHBondContact O-CB 3.48Å; I581-A585 PolarHBondContact O-N 2.93Å; I582-A585 PolarHBondContact O-N 3.32Å; A585-S587 VanDerWaalsContact C-N 3.35Å; A585-E588 PolarHBondContact O-N 2.86Å; A585-Y589 WeakPolarHBondContact O-CB 3.27Å; A585-Y589 WeakPolarHBondContact O-CD2 3.39Å; A585-Y589 PolarHBondContact O-N 2.93Å; A585-L595 HydrophobicContact CB-CD1 3.7Å; A585-L595 HydrophobicContact CB-CD2 4.38Å
586L96.6Very high95.4Very high17 Ų1751.4 Ų51.49%0.08926%0.262CS..Hα-helixtrans-75.6-18177.1-73.6168.5000113.6I582 E583 M584 E588 Y589 P590 L595 L596 K599I582-L586 HydrophobicContact CG2-CD1 3.73Å; I582-L586 HydrophobicContact CG2-CG 4.32Å; I582-L586 WeakPolarHBondContact O-CB 3.15Å; I582-L586 VanDerWaalsContact O-CG 3.26Å; I582-L586 WeakPolarHBondContact O-CG 3.39Å; I582-L586 PolarHBondContact O-N 3Å; E583-L586 PolarHBondContact O-N 2.97Å; M584-L586 VanDerWaalsContact C-N 3.28Å; M584-L586 PolarHBondContact O-N 3.23Å; L586-E588 VanDerWaalsContact C-N 3.32Å; L586-Y589 WeakPolarHBondContact CD2-O 3.12Å; L586-Y589 CarbonylContact O-C 3.55Å; L586-P590 WeakPolarHBondContact O-CA 3.41Å; L586-P590 VanDerWaalsContact O-N 3.14Å; L586-L595 HydrophobicContact CD2-CB 3.65Å; L586-L595 HydrophobicContact CD2-CD1 4.13Å; L586-L595 HydrophobicContact CG-CB 4.06Å; L586-L595 HydrophobicContact CG-CD1 4.35Å; L586-L596 HydrophobicContact CD1-CD2 3.81Å; L586-L596 HydrophobicContact CD2-CD2 3.73Å; L586-L596 HydrophobicContact CD2-CG 3.8Å; L586-L596 HydrophobicContact CG-CD2 4.44Å; L586-K599 HydrophobicContact CD1-CB 4.25Å; L586-K599 HydrophobicContact CD1-CD 3.49Å; L586-K599 VanDerWaalsContact CD1-CD 3.49Å; L586-K599 HydrophobicContact CD1-CG 4.44Å
587S95.2Very high95.3Very high80 Ų8046.4 Ų46.456%0.55924%0.239SC*.Hα-helixtrans-69-35.1171.167.90000111.6E583 M584 A585E583-S587 PolarHBondContact O-N 2.67Å; M584-S587 PolarHBondContact O-N 3.37Å; M584-S587 PolarHBondContact O-OG 3.25Å; A585-S587 VanDerWaalsContact C-N 3.35Å
588E94.4Very high95.3Very high123 Ų12342.4 Ų42.458%0.57522%0.217SC*.Hα-helixtrans-85-35.5174.6-59.4-53.213500112.5A585 L586 P590A585-E588 PolarHBondContact O-N 2.86Å; L586-E588 VanDerWaalsContact C-N 3.32Å; E588-P590 VanDerWaalsContact C-CD 3.42Å; E588-P590 WeakPolarHBondContact O-CD 3.35Å
589Y94.7Very high95.3Very high84 Ų8444.2 Ų44.233%0.32923%0.225SC..  trans-123.365.5-176.7-55.8-78.1000112.3D557 V559 A585 L586 E591 N592D557-Y589 WeakPolarHBondContact O-CE2 3.41Å; D557-Y589 PolarHBondContact O-OH 3.48Å; V559-Y589 HydrophobicContact CB-CD2 3.9Å; V559-Y589 HydrophobicContact CB-CE1 4.36Å; V559-Y589 HydrophobicContact CB-CE2 3.74Å; V559-Y589 HydrophobicContact CB-CG 4.29Å; V559-Y589 HydrophobicContact CG2-CD1 4.48Å; V559-Y589 HydrophobicContact CG2-CD2 3.78Å; V559-Y589 HydrophobicContact CG2-CE2 4.17Å; V559-Y589 HydrophobicContact CG2-CG 3.96Å; A585-Y589 WeakPolarHBondContact O-CB 3.27Å; A585-Y589 WeakPolarHBondContact O-CD2 3.39Å; A585-Y589 PolarHBondContact O-N 2.93Å; L586-Y589 WeakPolarHBondContact CD2-O 3.12Å; L586-Y589 CarbonylContact O-C 3.55Å; Y589-E591 PolarHBondContact O-N 2.8Å; Y589-N592 PolarHBondContact O-N 3.37Å
590P91.6Very high95.3Very high63 Ų6344.2 Ų44.241%0.40923%0.225SC..THydrogen-bonded Turntrans-62.1-20.8-171.921.1-31.4000114.3L586 E588 I622L586-P590 WeakPolarHBondContact O-CA 3.41Å; L586-P590 VanDerWaalsContact O-N 3.14Å; E588-P590 VanDerWaalsContact C-CD 3.42Å; E588-P590 WeakPolarHBondContact O-CD 3.35Å; P590-I622 WeakPolarHBondContact O-CD1 3.34Å
591E88.3Confident95.2Very high108 Ų10841.9 Ų41.951%0.50521%0.211SC..THydrogen-bonded Turntrans-106.36.2-169-56.9167151.800112.3Y589 F593 I622 F626Y589-E591 PolarHBondContact O-N 2.8Å; E591-F593 PolarHBondContact O-N 3.29Å; E591-I622 HydrophobicContact CB-CG2 4.37Å; E591-I622 HydrophobicContact CG-CG2 4.42Å; E591-F626 HydrophobicContact CB-CE2 3.71Å; E591-F626 HydrophobicContact CB-CZ 4Å; E591-F626 HydrophobicContact CG-CE2 3.54Å; E591-F626 HydrophobicContact CG-CZ 3.84Å; E591-F626 WeakPolarHBondContact OE1-CE2 3.24Å; E591-F626 VanDerWaalsContact OE1-CZ 3.22Å; E591-F626 WeakPolarHBondContact OE1-CZ 3.37Å; E591-F626 WeakPolarHBondContact OE2-CZ 3.31Å
592N92.8Very high95.2Very high41 Ų4140.2 Ų40.222%0.21920%0.202CC..  trans-80.6103.4-179.4-169.1-50.4000111.6V559 Y589 N594 L595 L596V559-N592 WeakPolarHBondContact CG2-ND2 3.42Å; Y589-N592 PolarHBondContact O-N 3.37Å; N592-N594 VanDerWaalsContact C-N 3.3Å; N592-N594 PolarHBondContact O-N 2.97Å; N592-N594 WeakPolarHBondContact OD1-CB 3.35Å; N592-N594 PolarHBondContact OD1-N 3.05Å; N592-L595 HydrophobicContact CB-CB 4.27Å; N592-L595 HydrophobicContact CB-CD1 4.01Å; N592-L595 HydrophobicContact CB-CG 4.08Å; N592-L595 PolarHBondContact O-N 2.83Å; N592-L595 PolarHBondContact OD1-N 3.25Å; N592-L596 WeakPolarHBondContact O-CG 3.49Å; N592-L596 PolarHBondContact O-N 3.4Å; N592-L596 VanDerWaalsContact O-N 3.09Å
593F92.3Very high95.1Very high25 Ų2540.9 Ų40.911%0.1121%0.205CC..Hα-helixtrans-60.7-31.8-179.5-70.3-82.6000114.2E591 L596 Y597 M619 I622 W623 T705 I709E591-F593 PolarHBondContact O-N 3.29Å; F593-L596 PolarHBondContact O-N 3.45Å; F593-Y597 HydrophobicContact CB-CE2 4.06Å; F593-Y597 WeakPolarHBondContact O-CD2 3.21Å; F593-Y597 PolarHBondContact O-N 3.41Å; F593-M619 HydrophobicContact CD1-CE 3.76Å; F593-M619 HydrophobicContact CE1-CB 4.39Å; F593-I622 HydrophobicContact CE1-CG2 4.43Å; F593-I622 HydrophobicContact CE2-CG2 4.32Å; F593-I622 HydrophobicContact CZ-CB 4.43Å; F593-I622 HydrophobicContact CZ-CG2 3.79Å; F593-W623 HydrophobicContact CE1-CB 4.34Å; F593-W623 HydrophobicContact CZ-CB 4.1Å; F593-T705 HydrophobicContact CB-CG2 4.11Å; F593-T705 HydrophobicContact CD1-CG2 3.54Å; F593-T705 HydrophobicContact CD2-CG2 3.79Å; F593-T705 HydrophobicContact CE1-CG2 3.85Å; F593-T705 HydrophobicContact CE2-CG2 4.06Å; F593-T705 HydrophobicContact CG-CG2 3.52Å; F593-T705 HydrophobicContact CZ-CG2 4.09Å; F593-I709 HydrophobicContact CD1-CD1 4.08Å; F593-I709 HydrophobicContact CD1-CG1 4.45Å; F593-I709 HydrophobicContact CE1-CD1 3.68Å
594N93.4Very high95Very high52 Ų5238.8 Ų38.828%0.27820%0.201SC..Hα-helixtrans-67.7-38.5178.3-73.2-25.9000112.2N592 T598N592-N594 VanDerWaalsContact C-N 3.3Å; N592-N594 PolarHBondContact O-N 2.97Å; N592-N594 WeakPolarHBondContact OD1-CB 3.35Å; N592-N594 PolarHBondContact OD1-N 3.05Å; N594-T598 PolarHBondContact O-N 3.01Å; N594-T598 PolarHBondContact O-OG1 3.16Å
595L96.6Very high94.8Very high0 Ų039.8 Ų39.80%021%0.206CC..Hα-helixtrans-65.6-44.5172.1-67-176.5000110.8V559 H563 I582 A585 L586 N592 Y597 T598 K599V559-L595 HydrophobicContact CG2-CD1 3.84Å; V559-L595 HydrophobicContact CG2-CG 4.32Å; H563-L595 HydrophobicContact CB-CD2 3.67Å; I582-L595 HydrophobicContact CD1-CD2 3.83Å; A585-L595 HydrophobicContact CB-CD1 3.7Å; A585-L595 HydrophobicContact CB-CD2 4.38Å; L586-L595 HydrophobicContact CD2-CB 3.65Å; L586-L595 HydrophobicContact CD2-CD1 4.13Å; L586-L595 HydrophobicContact CG-CB 4.06Å; L586-L595 HydrophobicContact CG-CD1 4.35Å; N592-L595 HydrophobicContact CB-CB 4.27Å; N592-L595 HydrophobicContact CB-CD1 4.01Å; N592-L595 HydrophobicContact CB-CG 4.08Å; N592-L595 PolarHBondContact O-N 2.83Å; N592-L595 PolarHBondContact OD1-N 3.25Å; L595-Y597 PolarHBondContact O-N 2.73Å; L595-T598 CarbonylContact O-C 3.56Å; L595-T598 WeakPolarHBondContact O-CB 3.39Å; L595-T598 PolarHBondContact O-N 3.35Å; L595-T598 VanDerWaalsContact O-N 3.12Å; L595-K599 PolarHBondContact O-N 3.39Å
596L96.6Very high94.6Very high3 Ų341.1 Ų41.12%0.01622%0.215CC..Hα-helixtrans-63-40178.1-67.7167.2000112.3L586 N592 F593 T598 K599 V600 T615 M619 I622L586-L596 HydrophobicContact CD1-CD2 3.81Å; L586-L596 HydrophobicContact CD2-CD2 3.73Å; L586-L596 HydrophobicContact CD2-CG 3.8Å; L586-L596 HydrophobicContact CG-CD2 4.44Å; N592-L596 WeakPolarHBondContact O-CG 3.49Å; N592-L596 PolarHBondContact O-N 3.4Å; N592-L596 VanDerWaalsContact O-N 3.09Å; F593-L596 PolarHBondContact O-N 3.45Å; L596-T598 VanDerWaalsContact C-N 3.27Å; L596-T598 PolarHBondContact O-N 2.7Å; L596-K599 WeakPolarHBondContact O-CB 3.48Å; L596-K599 PolarHBondContact O-N 3.02Å; L596-V600 WeakPolarHBondContact O-CG2 3.42Å; L596-V600 PolarHBondContact O-N 3.29Å; L596-T615 HydrophobicContact CD2-CG2 4.26Å; L596-M619 HydrophobicContact CB-CE 3.43Å; L596-M619 VanDerWaalsContact CB-CE 3.43Å; L596-M619 HydrophobicContact CB-CG 3.82Å; L596-M619 HydrophobicContact CB-SD 3.76Å; L596-M619 HydrophobicContact CD1-CE 4.44Å; L596-M619 HydrophobicContact CD1-CG 3.91Å; L596-M619 HydrophobicContact CG-CG 4.29Å; L596-I622 HydrophobicContact CD1-CD1 3.67Å
597Y95.7Very high94.4Very high7 Ų747.3 Ų47.33%0.02724%0.237CC..Hα-helixtrans-59.5-40.7172.8-63.3-38.2000111.7F593 L595 K601 M619 T705 Q708 I709 H712F593-Y597 HydrophobicContact CB-CE2 4.06Å; F593-Y597 WeakPolarHBondContact O-CD2 3.21Å; F593-Y597 PolarHBondContact O-N 3.41Å; L595-Y597 PolarHBondContact O-N 2.73Å; Y597-K601 WeakPolarHBondContact O-CG 3.49Å; Y597-K601 PolarHBondContact O-N 3.4Å; Y597-M619 HydrophobicContact CD1-CE 3.22Å; Y597-M619 HydrophobicContact CD1-SD 4.25Å; Y597-M619 HydrophobicContact CE1-CE 3.19Å; Y597-M619 HydrophobicContact CE1-SD 4.46Å; Y597-M619 HydrophobicContact CG-CE 4.14Å; Y597-T705 WeakPolarHBondContact OH-CG2 3.49Å; Y597-T705 PolarHBondContact OH-O 3.41Å; Y597-Q708 HydrophobicContact CE1-CB 4.19Å; Y597-Q708 VanDerWaalsContact OH-CB 3.25Å; Y597-Q708 WeakPolarHBondContact OH-CB 3.49Å; Y597-Q708 PolarHBondContact OH-OE1 3.18Å; Y597-I709 HydrophobicContact CE1-CG1 4.15Å; Y597-H712 AromaticContact CD1-CD2 3.18Å; Y597-H712 WeakPolarHBondContact CD1-CD2 3.48Å; Y597-H712 AromaticContact CD1-NE2 3.42Å; Y597-H712 WeakPolarHBondContact CD1-NE2 3.46Å; Y597-H712 AromaticContact CE1-CD2 3.5Å; Y597-H712 VanDerWaalsContact CE1-CD2 3.5Å; Y597-H712 WeakPolarHBondContact CE1-CD2 3.48Å; Y597-H712 AromaticContact CE1-NE2 3.93Å; Y597-H712 AromaticContact CG-CD2 3.92Å; Y597-H712 AromaticContact CG-NE2 3.64Å
598T96.9Very high94.3Very high0 Ų044.2 Ų44.20%022%0.218CC..Hα-helixtrans-68.3-38.8177.1-51.10000111.3H563 L567 I582 N594 L595 L596 K601 L602 I844 L845H563-T598 PolarHBondContact CE1-OG1 3.38Å; H563-T598 PolarHBondContact NE2-OG1 2.86Å; L567-T598 HydrophobicContact CD2-CG2 3.87Å; I582-T598 HydrophobicContact CD1-CG2 4.03Å; I582-T598 HydrophobicContact CG1-CG2 4.29Å; N594-T598 PolarHBondContact O-N 3.01Å; N594-T598 PolarHBondContact O-OG1 3.16Å; L595-T598 CarbonylContact O-C 3.56Å; L595-T598 WeakPolarHBondContact O-CB 3.39Å; L595-T598 PolarHBondContact O-N 3.35Å; L595-T598 VanDerWaalsContact O-N 3.12Å; L596-T598 VanDerWaalsContact C-N 3.27Å; L596-T598 PolarHBondContact O-N 2.7Å; T598-K601 PolarHBondContact O-N 3.1Å; T598-L602 HydrophobicContact CG2-CD1 4.09Å; T598-L602 WeakPolarHBondContact O-CG 3.49Å; T598-L602 PolarHBondContact O-N 3.12Å; T598-I844 HydrophobicContact CG2-CG2 4.19Å; T598-L845 HydrophobicContact CG2-CD1 4.46Å
599K97.7Very high94.1Very high39 Ų3940.8 Ų40.817%0.1721%0.206CC..Hα-helixtrans-58.6-52.3174-175.9169.4170.51700111.7L579 I582 L586 L595 L596 K601 L602 E603 T615L579-K599 HydrophobicContact CD1-CG 4.05Å; I582-K599 HydrophobicContact CG2-CB 3.71Å; I582-K599 HydrophobicContact CG2-CG 4.3Å; L586-K599 HydrophobicContact CD1-CB 4.25Å; L586-K599 HydrophobicContact CD1-CD 3.49Å; L586-K599 VanDerWaalsContact CD1-CD 3.49Å; L586-K599 HydrophobicContact CD1-CG 4.44Å; L595-K599 PolarHBondContact O-N 3.39Å; L596-K599 WeakPolarHBondContact O-CB 3.48Å; L596-K599 PolarHBondContact O-N 3.02Å; K599-K601 PolarHBondContact O-N 2.88Å; K599-L602 PolarHBondContact O-N 3.19Å; K599-L602 VanDerWaalsContact O-N 3.08Å; K599-E603 WeakPolarHBondContact CE-OE1 3.44Å; K599-E603 HydrophobicContact CG-CG 4.16Å; K599-E603 IonicContact NZ-OE1 3.3Å; K599-E603 WeakPolarHBondContact O-CB 3.28Å; K599-E603 WeakPolarHBondContact O-CG 3.28Å; K599-E603 PolarHBondContact O-N 3.06Å; K599-T615 HydrophobicContact CB-CG2 4.43Å; K599-T615 HydrophobicContact CD-CG2 4.12Å; K599-T615 HydrophobicContact CG-CG2 4.19Å
600V97.1Very high93.9Very high1 Ų141.9 Ų41.91%0.00621%0.214CC..Hα-helixtrans-52.4-42.8177.2170.60000110.8L596 A604 A612 T615 M619 V716L596-V600 WeakPolarHBondContact O-CG2 3.42Å; L596-V600 PolarHBondContact O-N 3.29Å; V600-A604 WeakPolarHBondContact O-CB 3.44Å; V600-A604 PolarHBondContact O-N 3.2Å; V600-A612 HydrophobicContact CG1-CB 4.16Å; V600-A612 WeakPolarHBondContact O-CB 3.41Å; V600-T615 HydrophobicContact CG2-CG2 3.57Å; V600-M619 HydrophobicContact CG2-SD 3.9Å; V600-V716 HydrophobicContact CG1-CG2 4.15Å
601K95.7Very high94Very high35 Ų3542.6 Ų42.615%0.15221%0.212CC..Hα-helixtrans-69.4-40.8179.3-70.1-66.5-173-179.10114Y597 T598 K599 M605 E715 I844 L845Y597-K601 WeakPolarHBondContact O-CG 3.49Å; Y597-K601 PolarHBondContact O-N 3.4Å; T598-K601 PolarHBondContact O-N 3.1Å; K599-K601 PolarHBondContact O-N 2.88Å; K601-M605 WeakPolarHBondContact O-CG 3.12Å; K601-M605 PolarHBondContact O-N 3.05Å; K601-E715 WeakPolarHBondContact CE-OE2 3.45Å; K601-E715 IonicContact NZ-OE1 3.53Å; K601-E715 PolarHBondContact NZ-OE1 2.88Å; K601-E715 IonicContact NZ-OE2 3.65Å; K601-E715 PolarHBondContact NZ-OE2 3.19Å; K601-I844 HydrophobicContact CB-CG1 3.71Å; K601-L845 HydrophobicContact CB-CG 4.44Å; K601-L845 HydrophobicContact CD-CD2 4.47Å; K601-L845 HydrophobicContact CG-CD1 4.14Å; K601-L845 HydrophobicContact CG-CD2 3.92Å; K601-L845 HydrophobicContact CG-CG 4.01Å
602L96.7Very high94.2Very high0 Ų037.4 Ų37.40%019%0.188CC..Hα-helixtrans-68.5-44.2176.7-72.3169.3000111.2Y575 A578 L579 I582 T598 K599 A604 M605 C606 I844Y575-L602 HydrophobicContact CD1-CD2 3.94Å; A578-L602 HydrophobicContact CB-CD1 4.01Å; A578-L602 HydrophobicContact CB-CD2 4.02Å; L579-L602 HydrophobicContact CB-CB 4.46Å; L579-L602 HydrophobicContact CD1-CB 4.15Å; I582-L602 HydrophobicContact CG1-CD1 3.88Å; T598-L602 HydrophobicContact CG2-CD1 4.09Å; T598-L602 WeakPolarHBondContact O-CG 3.49Å; T598-L602 PolarHBondContact O-N 3.12Å; K599-L602 PolarHBondContact O-N 3.19Å; K599-L602 VanDerWaalsContact O-N 3.08Å; L602-A604 VanDerWaalsContact C-N 3.35Å; L602-A604 PolarHBondContact O-N 3.31Å; L602-M605 PolarHBondContact O-N 3.08Å; L602-C606 PolarHBondContact O-N 3.08Å; L602-C606 PolarHBondContact O-SG 3.47Å; L602-I844 HydrophobicContact CD2-CB 4.21Å; L602-I844 HydrophobicContact CD2-CG1 4.29Å; L602-I844 HydrophobicContact CD2-CG2 3.92Å; L602-I844 HydrophobicContact CG-CG2 4.15Å
603E96.4Very high94.1Very high14 Ų1436 Ų367%0.06518%0.18CC..Hα-helixtrans-59.5-44.7177-73.1174.8152.700111.6L579 K599 M605 C606 R607 G608 E611 A612 T615L579-E603 HydrophobicContact CD1-CG 4.05Å; L579-E603 HydrophobicContact CD2-CG 4.36Å; K599-E603 WeakPolarHBondContact CE-OE1 3.44Å; K599-E603 HydrophobicContact CG-CG 4.16Å; K599-E603 IonicContact NZ-OE1 3.3Å; K599-E603 WeakPolarHBondContact O-CB 3.28Å; K599-E603 WeakPolarHBondContact O-CG 3.28Å; K599-E603 PolarHBondContact O-N 3.06Å; E603-M605 PolarHBondContact O-N 3.25Å; E603-M605 VanDerWaalsContact O-N 3.15Å; E603-C606 PolarHBondContact O-N 3.34Å; E603-R607 WeakPolarHBondContact O-CA 3.49Å; E603-R607 PolarHBondContact O-N 2.94Å; E603-G608 PolarHBondContact O-N 2.65Å; E603-E611 HydrophobicContact CB-CB 4.41Å; E603-A612 HydrophobicContact CB-CB 4.13Å; E603-T615 VanDerWaalsContact CD-OG1 3.28Å; E603-T615 PolarHBondContact OE1-OG1 3.47Å; E603-T615 WeakPolarHBondContact OE2-CB 3.34Å; E603-T615 PolarHBondContact OE2-OG1 3.42Å
604A94Very high94Very high31 Ų3140.3 Ų40.326%0.25620%0.204SC..Hα-helixtrans-58.8-27.9175.900000113.1V600 L602 A612V600-A604 WeakPolarHBondContact O-CB 3.44Å; V600-A604 PolarHBondContact O-N 3.2Å; L602-A604 VanDerWaalsContact C-N 3.35Å; L602-A604 PolarHBondContact O-N 3.31Å; A604-A612 HydrophobicContact CB-CB 4.06Å
605M92.8Very high94Very high113 Ų11338.2 Ų38.256%0.55719%0.193SC*.Hα-helixtrans-88.5-37.8178.6-67-60.797.600114.1K601 L602 E603 I844K601-M605 WeakPolarHBondContact O-CG 3.12Å; K601-M605 PolarHBondContact O-N 3.05Å; L602-M605 PolarHBondContact O-N 3.08Å; E603-M605 PolarHBondContact O-N 3.25Å; E603-M605 VanDerWaalsContact O-N 3.15Å; M605-I844 HydrophobicContact CG-CD1 3.44Å; M605-I844 VanDerWaalsContact CG-CD1 3.44Å; M605-I844 HydrophobicContact SD-CD1 4.34Å
606C92.4Very high93.7Very high28 Ų2838.2 Ų38.219%0.18919%0.193CC..Hα-helixtrans-117.4-14-168.773.30000115.8L602 E603L602-C606 PolarHBondContact O-N 3.08Å; L602-C606 PolarHBondContact O-SG 3.47Å; E603-C606 PolarHBondContact O-N 3.34Å
607R92.4Very high93.3Very high146 Ų14642 Ų4255%0.55121%0.21SC*.THydrogen-bonded Turntrans-113-50.3178-66.7-69.6-172.1167.81111.6L579 E603 E611L579-R607 HydrophobicContact CD2-CG 4.07Å; E603-R607 WeakPolarHBondContact O-CA 3.49Å; E603-R607 PolarHBondContact O-N 2.94Å; R607-E611 HydrophobicContact CB-CB 4.11Å; R607-E611 HydrophobicContact CB-CG 4.01Å
608G91.7Very high93Very high16 Ų1645.8 Ų45.817%0.16523%0.227CC..  trans144.5166.3-17500000112.2E603 E610 E611E603-G608 PolarHBondContact O-N 2.65Å; G608-E610 VanDerWaalsContact C-N 3.33Å; G608-E611 WeakPolarHBondContact CA-OE2 3.31Å
609P91.6Very high92.7Very high50 Ų5045.8 Ų45.833%0.32523%0.227SC..Hα-helixtrans-71.4-26.3179.229-34.8000113.2A612 L613 V716 M720P609-A612 PolarHBondContact O-N 3.35Å; P609-L613 WeakPolarHBondContact O-CG 3.45Å; P609-L613 PolarHBondContact O-N 2.79Å; P609-V716 HydrophobicContact CB-CG1 3.58Å; P609-V716 WeakPolarHBondContact O-CG1 3.48Å; P609-M720 HydrophobicContact CB-CE 4.4Å; P609-M720 HydrophobicContact CB-CG 3.52Å; P609-M720 HydrophobicContact CB-SD 3.76Å; P609-M720 HydrophobicContact CG-CE 4.12Å; P609-M720 HydrophobicContact CG-CG 3.73Å; P609-M720 HydrophobicContact CG-SD 4.11Å
610E89.8Confident92.2Very high107 Ų10744.2 Ų44.250%0.522%0.221SC..Hα-helixtrans-67.5-44.3-179.2-62.5-64.3164.500111.3G608 A612 L613 L614 M720G608-E610 VanDerWaalsContact C-N 3.33Å; E610-A612 VanDerWaalsContact C-N 3.34Å; E610-A612 PolarHBondContact O-N 3.34Å; E610-L613 PolarHBondContact O-N 3.36Å; E610-L614 WeakPolarHBondContact O-CG 3.45Å; E610-L614 PolarHBondContact O-N 2.75Å; E610-M720 WeakPolarHBondContact OE1-CE 3.44Å
611E92.9Very high91.7Very high78 Ų7849 Ų4936%0.36424%0.243SC..Hα-helixtrans-61.4-42.6174.3-68.881.8177.900111.8E603 R607 G608 L613 L614 T615E603-E611 HydrophobicContact CB-CB 4.41Å; R607-E611 HydrophobicContact CB-CB 4.11Å; R607-E611 HydrophobicContact CB-CG 4.01Å; G608-E611 WeakPolarHBondContact CA-OE2 3.31Å; E611-L613 VanDerWaalsContact C-N 3.31Å; E611-L613 PolarHBondContact O-N 3Å; E611-L614 WeakPolarHBondContact O-CB 3.44Å; E611-L614 PolarHBondContact O-N 3.21Å; E611-L614 VanDerWaalsContact O-N 3.15Å; E611-T615 PolarHBondContact O-N 3.13Å
612A92.7Very high91.3Very high0 Ų048 Ų480%024%0.239CC..Hα-helixtrans-61.2-39.117700000112.1V600 E603 A604 P609 E610 T615 C616 V716V600-A612 HydrophobicContact CG1-CB 4.16Å; V600-A612 WeakPolarHBondContact O-CB 3.41Å; E603-A612 HydrophobicContact CB-CB 4.13Å; A604-A612 HydrophobicContact CB-CB 4.06Å; P609-A612 PolarHBondContact O-N 3.35Å; E610-A612 VanDerWaalsContact C-N 3.34Å; E610-A612 PolarHBondContact O-N 3.34Å; A612-T615 PolarHBondContact O-N 3.32Å; A612-C616 PolarHBondContact O-N 3.24Å; A612-C616 PolarHBondContact O-SG 3.26Å; A612-V716 HydrophobicContact CB-CG1 4.36Å; A612-V716 HydrophobicContact CB-CG2 4.06Å
613L90.5Very high90.8Very high11 Ų1148.6 Ų48.66%0.05824%0.241CC..Hα-helixtrans-68.6-35.7174.8-72.1173000112.5P609 E610 E611 T615 C616 K617 L657 A713 V716 Y717 M720P609-L613 WeakPolarHBondContact O-CG 3.45Å; P609-L613 PolarHBondContact O-N 2.79Å; E610-L613 PolarHBondContact O-N 3.36Å; E611-L613 VanDerWaalsContact C-N 3.31Å; E611-L613 PolarHBondContact O-N 3Å; L613-T615 VanDerWaalsContact C-N 3.32Å; L613-C616 WeakPolarHBondContact O-CB 3.46Å; L613-C616 PolarHBondContact O-N 2.92Å; L613-K617 PolarHBondContact O-N 3.01Å; L613-L657 WeakPolarHBondContact O-CD1 3.35Å; L613-A713 HydrophobicContact CD2-CB 4.29Å; L613-V716 HydrophobicContact CD1-CG1 4.34Å; L613-V716 HydrophobicContact CD2-CB 4.05Å; L613-V716 HydrophobicContact CD2-CG1 4.05Å; L613-V716 HydrophobicContact CG-CB 4.36Å; L613-V716 HydrophobicContact CG-CG1 3.8Å; L613-Y717 HydrophobicContact CD1-CD1 4.2Å; L613-Y717 HydrophobicContact CD1-CE1 3.59Å; L613-Y717 HydrophobicContact CD1-CE2 4.44Å; L613-Y717 HydrophobicContact CD2-CD2 4.17Å; L613-Y717 HydrophobicContact CD2-CE1 4.36Å; L613-Y717 HydrophobicContact CD2-CE2 3.75Å; L613-M720 HydrophobicContact CD1-SD 3.89Å
614L90.9Very high90Very high115 Ų11550.1 Ų50.160%0.60225%0.248SC*.Hα-helixtrans-61.2-42.1171.8-70.9173.9000111.2E610 E611 K617 H618E610-L614 WeakPolarHBondContact O-CG 3.45Å; E610-L614 PolarHBondContact O-N 2.75Å; E611-L614 WeakPolarHBondContact O-CB 3.44Å; E611-L614 PolarHBondContact O-N 3.21Å; E611-L614 VanDerWaalsContact O-N 3.15Å; L614-K617 WeakPolarHBondContact O-CB 3.4Å; L614-K617 PolarHBondContact O-N 3.08Å; L614-H618 PolarHBondContact O-N 2.85Å
615T93Very high89.4Confident9 Ų952.2 Ų52.26%0.05526%0.261CS..Hα-helixtrans-63.5-44.1173.3-63.10000111.1L596 K599 V600 E603 E611 A612 L613 K617 H618 M619L596-T615 HydrophobicContact CD2-CG2 4.26Å; K599-T615 HydrophobicContact CB-CG2 4.43Å; K599-T615 HydrophobicContact CD-CG2 4.12Å; K599-T615 HydrophobicContact CG-CG2 4.19Å; V600-T615 HydrophobicContact CG2-CG2 3.57Å; E603-T615 VanDerWaalsContact CD-OG1 3.28Å; E603-T615 PolarHBondContact OE1-OG1 3.47Å; E603-T615 WeakPolarHBondContact OE2-CB 3.34Å; E603-T615 PolarHBondContact OE2-OG1 3.42Å; E611-T615 PolarHBondContact O-N 3.13Å; A612-T615 PolarHBondContact O-N 3.32Å; L613-T615 VanDerWaalsContact C-N 3.32Å; T615-K617 VanDerWaalsContact C-N 3.3Å; T615-K617 PolarHBondContact O-N 3.19Å; T615-H618 CarbonylContact O-C 3.49Å; T615-H618 WeakPolarHBondContact O-CA 3.28Å; T615-H618 WeakPolarHBondContact O-CB 3.32Å; T615-H618 PolarHBondContact O-N 2.93Å; T615-M619 HydrophobicContact CG2-CG 4.5Å; T615-M619 VanDerWaalsContact O-CG 3.27Å; T615-M619 WeakPolarHBondContact O-CG 3.17Å; T615-M619 PolarHBondContact O-N 2.84Å
616C90.2Very high88.3Confident0 Ų051.2 Ų51.20%025%0.253CS..Hα-helixtrans-56.9-41.5172.8-72.30000112.6A612 L613 H618 M619 L620 A713A612-C616 PolarHBondContact O-N 3.24Å; A612-C616 PolarHBondContact O-SG 3.26Å; L613-C616 WeakPolarHBondContact O-CB 3.46Å; L613-C616 PolarHBondContact O-N 2.92Å; C616-H618 VanDerWaalsContact C-N 3.32Å; C616-H618 PolarHBondContact O-N 2.83Å; C616-M619 WeakPolarHBondContact O-CB 3.29Å; C616-M619 PolarHBondContact O-N 3.27Å; C616-L620 WeakPolarHBondContact O-CG 3.19Å; C616-L620 PolarHBondContact O-N 3.11Å; C616-A713 HydrophobicContact CB-CB 4.19Å
617K87.6Confident87.2Confident83 Ų8353.7 Ų53.736%0.36126%0.259SS..Hα-helixtrans-61.2-42.1174.6-167.7176-179.6172.10111.2L613 L614 T615 L620 Q621 L657L613-K617 PolarHBondContact O-N 3.01Å; L614-K617 WeakPolarHBondContact O-CB 3.4Å; L614-K617 PolarHBondContact O-N 3.08Å; T615-K617 VanDerWaalsContact C-N 3.3Å; T615-K617 PolarHBondContact O-N 3.19Å; K617-L620 PolarHBondContact O-N 3.47Å; K617-Q621 WeakPolarHBondContact O-CG 3.45Å; K617-Q621 PolarHBondContact O-N 3.44Å; K617-Q621 VanDerWaalsContact O-N 3.09Å; K617-L657 HydrophobicContact CB-CD1 3.83Å; K617-L657 HydrophobicContact CG-CD1 4.47Å
618H90.9Very high85.2Confident85 Ų8551.1 Ų51.139%0.39426%0.256SS..Hα-helixtrans-64-42175.6-176.554.3000112L614 T615 C616 L620 Q621 I622L614-H618 PolarHBondContact O-N 2.85Å; T615-H618 CarbonylContact O-C 3.49Å; T615-H618 WeakPolarHBondContact O-CA 3.28Å; T615-H618 WeakPolarHBondContact O-CB 3.32Å; T615-H618 PolarHBondContact O-N 2.93Å; C616-H618 VanDerWaalsContact C-N 3.32Å; C616-H618 PolarHBondContact O-N 2.83Å; H618-L620 VanDerWaalsContact C-N 3.3Å; H618-L620 PolarHBondContact O-N 3.35Å; H618-Q621 WeakPolarHBondContact O-CA 3.48Å; H618-Q621 WeakPolarHBondContact O-CB 3.24Å; H618-Q621 PolarHBondContact O-N 3.47Å; H618-I622 WeakPolarHBondContact NE2-CD1 3.37Å; H618-I622 WeakPolarHBondContact O-CG1 3.29Å; H618-I622 PolarHBondContact O-N 3.02Å
619M90.6Very high83Confident0 Ų056.5 Ų56.50%028%0.281CS..Hα-helixtrans-59.7-40.1174.4-63176.381.900112.1F593 L596 Y597 V600 T615 C616 Q621 I622 W623 I709F593-M619 HydrophobicContact CD1-CE 3.76Å; F593-M619 HydrophobicContact CE1-CB 4.39Å; L596-M619 HydrophobicContact CB-CE 3.43Å; L596-M619 VanDerWaalsContact CB-CE 3.43Å; L596-M619 HydrophobicContact CB-CG 3.82Å; L596-M619 HydrophobicContact CB-SD 3.76Å; L596-M619 HydrophobicContact CD1-CE 4.44Å; L596-M619 HydrophobicContact CD1-CG 3.91Å; L596-M619 HydrophobicContact CG-CG 4.29Å; Y597-M619 HydrophobicContact CD1-CE 3.22Å; Y597-M619 HydrophobicContact CD1-SD 4.25Å; Y597-M619 HydrophobicContact CE1-CE 3.19Å; Y597-M619 HydrophobicContact CE1-SD 4.46Å; Y597-M619 HydrophobicContact CG-CE 4.14Å; V600-M619 HydrophobicContact CG2-SD 3.9Å; T615-M619 HydrophobicContact CG2-CG 4.5Å; T615-M619 VanDerWaalsContact O-CG 3.27Å; T615-M619 WeakPolarHBondContact O-CG 3.17Å; T615-M619 PolarHBondContact O-N 2.84Å; C616-M619 WeakPolarHBondContact O-CB 3.29Å; C616-M619 PolarHBondContact O-N 3.27Å; M619-Q621 VanDerWaalsContact C-N 3.32Å; M619-Q621 PolarHBondContact O-N 3.19Å; M619-I622 PolarHBondContact O-N 2.96Å; M619-W623 WeakPolarHBondContact O-CB 2.99Å; M619-W623 PolarHBondContact O-N 3.36Å; M619-I709 HydrophobicContact CB-CD1 3.97Å; M619-I709 HydrophobicContact CB-CG1 4.04Å; M619-I709 HydrophobicContact CB-CG2 3.99Å; M619-I709 HydrophobicContact CE-CG1 4.07Å
620L86.5Confident80.1Confident6 Ų660.7 Ų60.73%0.03131%0.306CS..Hα-helixtrans-64.3-36.2173.5-68.5175000112C616 K617 H618 K624 L657 L706 I709 W710C616-L620 WeakPolarHBondContact O-CG 3.19Å; C616-L620 PolarHBondContact O-N 3.11Å; K617-L620 PolarHBondContact O-N 3.47Å; H618-L620 VanDerWaalsContact C-N 3.3Å; H618-L620 PolarHBondContact O-N 3.35Å; L620-K624 WeakPolarHBondContact O-CB 3.45Å; L620-K624 VanDerWaalsContact O-CG 3.22Å; L620-K624 WeakPolarHBondContact O-CG 3.27Å; L620-K624 PolarHBondContact O-N 2.76Å; L620-L657 HydrophobicContact CD1-CD2 4.37Å; L620-L657 HydrophobicContact CD1-CG 4.31Å; L620-L706 HydrophobicContact CD2-CD1 3.45Å; L620-L706 VanDerWaalsContact CD2-CD1 3.45Å; L620-I709 HydrophobicContact CD2-CB 4.25Å; L620-I709 HydrophobicContact CD2-CD1 4.47Å; L620-I709 HydrophobicContact CD2-CG2 3.62Å; L620-I709 HydrophobicContact CG-CG2 3.75Å; L620-W710 HydrophobicContact CD1-CH2 3.98Å; L620-W710 HydrophobicContact CD1-CZ2 4.06Å; L620-W710 HydrophobicContact CD1-CZ3 4.36Å; L620-W710 HydrophobicContact CD2-CZ2 4.22Å
621Q86.4Confident77.3Confident103 Ų10360.3 Ų60.348%0.48131%0.307SS..Hα-helixtrans-67.4-44.8175.7-69.1167.9-12.700111.7K617 H618 M619 K624 S625K617-Q621 WeakPolarHBondContact O-CG 3.45Å; K617-Q621 PolarHBondContact O-N 3.44Å; K617-Q621 VanDerWaalsContact O-N 3.09Å; H618-Q621 WeakPolarHBondContact O-CA 3.48Å; H618-Q621 WeakPolarHBondContact O-CB 3.24Å; H618-Q621 PolarHBondContact O-N 3.47Å; M619-Q621 VanDerWaalsContact C-N 3.32Å; M619-Q621 PolarHBondContact O-N 3.19Å; Q621-K624 WeakPolarHBondContact O-CB 3.47Å; Q621-K624 PolarHBondContact O-N 3.04Å; Q621-S625 PolarHBondContact O-N 2.9Å
622I86.7Confident74.5Confident12 Ų1261.6 Ų61.66%0.06232%0.322CS..Hα-helixtrans-59.2-50.5173.5-67.4168.1000109.4P590 E591 F593 L596 H618 M619 K624 S625 F626P590-I622 WeakPolarHBondContact O-CD1 3.34Å; E591-I622 HydrophobicContact CB-CG2 4.37Å; E591-I622 HydrophobicContact CG-CG2 4.42Å; F593-I622 HydrophobicContact CE1-CG2 4.43Å; F593-I622 HydrophobicContact CE2-CG2 4.32Å; F593-I622 HydrophobicContact CZ-CB 4.43Å; F593-I622 HydrophobicContact CZ-CG2 3.79Å; L596-I622 HydrophobicContact CD1-CD1 3.67Å; H618-I622 WeakPolarHBondContact NE2-CD1 3.37Å; H618-I622 WeakPolarHBondContact O-CG1 3.29Å; H618-I622 PolarHBondContact O-N 3.02Å; M619-I622 PolarHBondContact O-N 2.96Å; I622-K624 VanDerWaalsContact C-N 3.26Å; I622-K624 PolarHBondContact O-N 3.47Å; I622-S625 PolarHBondContact O-N 3.2Å; I622-S625 PolarHBondContact O-OG 2.89Å; I622-F626 HydrophobicContact CG2-CD2 3.62Å; I622-F626 HydrophobicContact CG2-CE2 3.75Å; I622-F626 VanDerWaalsContact O-CD2 3.26Å; I622-F626 WeakPolarHBondContact O-CD2 3.27Å; I622-F626 PolarHBondContact O-N 3.12Å
623W85.9Confident71.8Confident14 Ų1465.2 Ų65.25%0.05335%0.347CS..Hα-helixtrans-56.1-43.6178.5-172.794.1000111.6F593 M619 F626 Y627 M655 P702 W703 L706 I709F593-W623 HydrophobicContact CE1-CB 4.34Å; F593-W623 HydrophobicContact CZ-CB 4.1Å; M619-W623 WeakPolarHBondContact O-CB 2.99Å; M619-W623 PolarHBondContact O-N 3.36Å; W623-F626 PolarHBondContact O-N 3.17Å; W623-Y627 AromaticContact CD1-CD2 3.43Å; W623-Y627 VanDerWaalsContact CD1-CD2 3.43Å; W623-Y627 AromaticContact CD1-CE2 3.48Å; W623-Y627 VanDerWaalsContact CD1-CE2 3.48Å; W623-Y627 AromaticContact CD2-CD2 3.72Å; W623-Y627 HydrophobicContact CD2-CD2 3.72Å; W623-Y627 AromaticContact CE2-CD2 3.44Å; W623-Y627 VanDerWaalsContact CE2-CD2 3.44Å; W623-Y627 AromaticContact CG-CD2 3.69Å; W623-Y627 HydrophobicContact CG-CD2 3.69Å; W623-Y627 HydrophobicContact CG-CE2 4.11Å; W623-Y627 HydrophobicContact CZ2-CD2 4.09Å; W623-Y627 HydrophobicContact CZ2-CG 4.31Å; W623-Y627 AromaticContact NE1-CD2 3.26Å; W623-Y627 VanDerWaalsContact NE1-CD2 3.26Å; W623-Y627 AromaticContact NE1-CE2 3.51Å; W623-Y627 WeakPolarHBondContact O-CD2 3.43Å; W623-Y627 PolarHBondContact O-N 2.92Å; W623-M655 HydrophobicContact CZ3-SD 4.25Å; W623-P702 PolarHBondContact NE1-O 3.45Å; W623-W703 HydrophobicContact CH2-CE3 4.21Å; W623-W703 HydrophobicContact CH2-CH2 4.29Å; W623-W703 AromaticContact CH2-CZ3 3.74Å; W623-W703 HydrophobicContact CH2-CZ3 3.74Å; W623-W703 AromaticContact CZ2-CE3 3.99Å; W623-W703 HydrophobicContact CZ2-CE3 3.99Å; W623-W703 HydrophobicContact CZ2-CZ3 4.01Å; W623-L706 HydrophobicContact CD2-CB 4.19Å; W623-L706 HydrophobicContact CD2-CD1 3.9Å; W623-L706 HydrophobicContact CD2-CD2 4.25Å; W623-L706 HydrophobicContact CD2-CG 4.33Å; W623-L706 HydrophobicContact CE3-CD1 4.07Å; W623-L706 HydrophobicContact CE3-CD2 4.16Å; W623-L706 HydrophobicContact CG-CB 4.48Å; W623-L706 HydrophobicContact CG-CD1 4.18Å; W623-L706 HydrophobicContact CH2-CD2 3.65Å; W623-L706 HydrophobicContact CZ2-CB 4Å; W623-L706 HydrophobicContact CZ2-CD2 3.71Å; W623-L706 HydrophobicContact CZ2-CG 4.35Å; W623-L706 HydrophobicContact CZ3-CD2 3.88Å; W623-I709 HydrophobicContact CB-CD1 4.11Å; W623-I709 HydrophobicContact CG-CD1 4.44Å
624K80.3Confident68.8Low46 Ų4672.6 Ų72.620%0.239%0.387CS..Hα-helixtrans-61.5-48.3173.5-72.1171.7-167.3-174.60111.8L620 Q621 I622 F626 Y627 N628 M655L620-K624 WeakPolarHBondContact O-CB 3.45Å; L620-K624 VanDerWaalsContact O-CG 3.22Å; L620-K624 WeakPolarHBondContact O-CG 3.27Å; L620-K624 PolarHBondContact O-N 2.76Å; Q621-K624 WeakPolarHBondContact O-CB 3.47Å; Q621-K624 PolarHBondContact O-N 3.04Å; I622-K624 VanDerWaalsContact C-N 3.26Å; I622-K624 PolarHBondContact O-N 3.47Å; K624-F626 PolarHBondContact O-N 3.27Å; K624-Y627 PolarHBondContact O-N 3.41Å; K624-N628 WeakPolarHBondContact O-CA 3.27Å; K624-N628 WeakPolarHBondContact O-CB 3.45Å; K624-N628 PolarHBondContact O-N 3.43Å; K624-N628 PolarHBondContact O-ND2 2.91Å; K624-N628 PolarHBondContact O-OD1 3.25Å; K624-M655 HydrophobicContact CD-CE 4.28Å; K624-M655 WeakPolarHBondContact CE-O 3.37Å; K624-M655 HydrophobicContact CG-CE 4.06Å; K624-M655 HydrophobicContact CG-SD 4.38Å; K624-M655 VanDerWaalsContact NZ-CB 3.34Å; K624-M655 PolarHBondContact NZ-O 3.48Å
625S81.7Confident66Low75 Ų7572.4 Ų72.452%0.52440%0.395SS..Hα-helixtrans-59-35.7-17962.50000112.5Q621 I622Q621-S625 PolarHBondContact O-N 2.9Å; I622-S625 PolarHBondContact O-N 3.2Å; I622-S625 PolarHBondContact O-OG 2.89Å
626F70Confident63Low91 Ų9175.5 Ų75.540%0.39943%0.429SS..Hα-helixtrans-72.7-46.8177.5-89.4-72.1000114.5E591 I622 W623 K624E591-F626 HydrophobicContact CB-CE2 3.71Å; E591-F626 HydrophobicContact CB-CZ 4Å; E591-F626 HydrophobicContact CG-CE2 3.54Å; E591-F626 HydrophobicContact CG-CZ 3.84Å; E591-F626 WeakPolarHBondContact OE1-CE2 3.24Å; E591-F626 VanDerWaalsContact OE1-CZ 3.22Å; E591-F626 WeakPolarHBondContact OE1-CZ 3.37Å; E591-F626 WeakPolarHBondContact OE2-CZ 3.31Å; I622-F626 HydrophobicContact CG2-CD2 3.62Å; I622-F626 HydrophobicContact CG2-CE2 3.75Å; I622-F626 VanDerWaalsContact O-CD2 3.26Å; I622-F626 WeakPolarHBondContact O-CD2 3.27Å; I622-F626 PolarHBondContact O-N 3.12Å; W623-F626 PolarHBondContact O-N 3.17Å; K624-F626 PolarHBondContact O-N 3.27Å
627Y69.3Low60.3Low80 Ų8087.8 Ų87.831%0.31448%0.475SS..Hα-helixtrans-109.814.5-168.9-52.3-67000112.2W623 K624 L629 P702W623-Y627 AromaticContact CD1-CD2 3.43Å; W623-Y627 VanDerWaalsContact CD1-CD2 3.43Å; W623-Y627 AromaticContact CD1-CE2 3.48Å; W623-Y627 VanDerWaalsContact CD1-CE2 3.48Å; W623-Y627 AromaticContact CD2-CD2 3.72Å; W623-Y627 HydrophobicContact CD2-CD2 3.72Å; W623-Y627 AromaticContact CE2-CD2 3.44Å; W623-Y627 VanDerWaalsContact CE2-CD2 3.44Å; W623-Y627 AromaticContact CG-CD2 3.69Å; W623-Y627 HydrophobicContact CG-CD2 3.69Å; W623-Y627 HydrophobicContact CG-CE2 4.11Å; W623-Y627 HydrophobicContact CZ2-CD2 4.09Å; W623-Y627 HydrophobicContact CZ2-CG 4.31Å; W623-Y627 AromaticContact NE1-CD2 3.26Å; W623-Y627 VanDerWaalsContact NE1-CD2 3.26Å; W623-Y627 AromaticContact NE1-CE2 3.51Å; W623-Y627 WeakPolarHBondContact O-CD2 3.43Å; W623-Y627 PolarHBondContact O-N 2.92Å; K624-Y627 PolarHBondContact O-N 3.41Å; Y627-L629 VanDerWaalsContact C-N 3.28Å; Y627-L629 PolarHBondContact O-N 2.89Å; Y627-P702 HydrophobicContact CD1-CB 3.76Å; Y627-P702 HydrophobicContact CD1-CG 3.79Å; Y627-P702 HydrophobicContact CD2-CB 4.06Å; Y627-P702 HydrophobicContact CE1-CB 3.54Å; Y627-P702 HydrophobicContact CE1-CG 3.22Å; Y627-P702 HydrophobicContact CE2-CB 3.86Å; Y627-P702 HydrophobicContact CE2-CG 4.32Å; Y627-P702 HydrophobicContact CG-CB 4.02Å
628N49.4Very low57.5Low92 Ų9287.5 Ų87.549%0.49250%0.496SS..  trans-55.597.7165.7-90.2-18.4000107.3K624 T630K624-N628 WeakPolarHBondContact O-CA 3.27Å; K624-N628 WeakPolarHBondContact O-CB 3.45Å; K624-N628 PolarHBondContact O-N 3.43Å; K624-N628 PolarHBondContact O-ND2 2.91Å; K624-N628 PolarHBondContact O-OD1 3.25Å; N628-T630 PolarHBondContact O-N 3.19Å
629L46Very low54.6Low130 Ų13089.2 Ų89.268%0.68152%0.517SS*.  trans-25110.2165.1-70.6141.8000110.1Y627 N631 L652Y627-L629 VanDerWaalsContact C-N 3.28Å; Y627-L629 PolarHBondContact O-N 2.89Å; L629-N631 VanDerWaalsContact C-N 3.3Å; L629-N631 PolarHBondContact O-N 3.28Å; L629-L652 HydrophobicContact CD1-CD1 4.26Å
630T31.5Very low51.8Low138 Ų13894 Ų9485%0.84755%0.551SS**  trans-49.399.6158.334.40000107.8N628 P632N628-T630 PolarHBondContact O-N 3.19Å; T630-P632 VanDerWaalsContact O-CD 3.29Å; T630-P632 WeakPolarHBondContact O-CD 3.32Å
631N30.5Very low49.1Very low98 Ų98101.7 Ų101.752%0.52459%0.591SS.*  trans-70.2119.1156.9-101.7-28.7000106.4L629 S633L629-N631 VanDerWaalsContact C-N 3.3Å; L629-N631 PolarHBondContact O-N 3.28Å; N631-S633 PolarHBondContact O-N 3.25Å
632P33.5Very low46.5Very low105 Ų105104.3 Ų104.368%0.68261%0.608SS**  trans-79.848.9170.434.5-33.8000110.5T630T630-P632 VanDerWaalsContact O-CD 3.29Å; T630-P632 WeakPolarHBondContact O-CD 3.32Å
633S36.2Very low43.8Very low76 Ų76111 Ų11153%0.53164%0.644SS.*  trans-138.650.2-174.973.90000112.8N631N631-S633 PolarHBondContact O-N 3.25Å
634D27.8Very low41Very low167 Ų167121.9 Ų121.989%0.89369%0.685SS**SBendtrans-158.738.9147.3-132.62.2000115
635S31Very low38.6Very low111 Ų111124.3 Ų124.378%0.77671%0.713SS**  trans-107.996.4158.7470000108.9R637S635-R637 PolarHBondContact O-N 3.25Å
636G30.2Very low36.2Very low74 Ų74128.4 Ų128.476%0.76373%0.728SS**  trans-56.9121.5174.200000112.1
637R33.3Very low34.5Very low257 Ų257130 Ų13097%0.9775%0.747SS**SBendtrans62.6100.8157.4-65.6-172.8-178.8-145.50.8118.1S635S635-R637 PolarHBondContact O-N 3.25Å
638G28.7Very low32.6Very low78 Ų78131.9 Ų131.980%0.80476%0.763SS**  trans165.1107.7156.400000111.4
639S31.9Very low31.7Very low120 Ų120136.5 Ų136.584%0.83977%0.773SS**  trans-66.1130.1-167.7-175.40000114.5
640S30.4Very low31.2Very low102 Ų102141 Ų14171%0.71378%0.781SS**  trans-132.3128.2158.21740000109.4L642S640-L642 PolarHBondContact O-N 3.46Å
641L30.1Very low31.6Very low166 Ų166140.8 Ų140.887%0.86977%0.771SS**THydrogen-bonded Turntrans-86.443.8-162.9-99.9163.5000113.9
642L32.6Very low32.1Very low159 Ų159139.4 Ų139.483%0.83276%0.763SS**THydrogen-bonded Turntrans-132.84.9-173.7-81.3170.6000118S640S640-L642 PolarHBondContact O-N 3.46Å
643D28.8Very low32Very low153 Ų153142 Ų14282%0.81877%0.771SS**  trans-111.5117.2-178.8-109.4-23.8000113.1
644R28.5Very low32.2Very low241 Ų241142 Ų14291%0.90978%0.776SS**  trans-130.6124.4176.6-173.2173.2154.8162.4-5.4111.4
645A28.3Very low33.1Very low97 Ų97135.8 Ų135.880%0.80274%0.742SS**  trans99.6122.6152.300000119.9
646I32.7Very low33.6Very low161 Ų161135 Ų13583%0.82673%0.733SS**  trans-99.3144176.6-65.1163.8000109.6
647P33.1Very low33.9Very low125 Ų125132.3 Ų132.381%0.81270%0.701SS**  -147165.1100.930.1-9.1000113.3
648D29.4Very low34.3Very low119 Ų119121.8 Ų121.864%0.63667%0.666SS**  cis-162.7145.2-13.4-169.32.5000106.2R650D648-R650 VanDerWaalsContact C-N 3.32Å; D648-R650 PolarHBondContact O-N 3.09Å; D648-R650 VanDerWaalsContact O-N 3.15Å
649R31.4Very low34.6Very low189 Ų189124.3 Ų124.371%0.71366%0.661SS**THydrogen-bonded Turntrans-82.310.9-158.6-145.5176.3179.51771.5115.5
650R36.1Very low35.4Very low225 Ų225125.6 Ų125.685%0.84965%0.651SS**THydrogen-bonded Turntrans-96.6-11.6-168.5-67.9-178.1-179.6176.71115.9D648D648-R650 VanDerWaalsContact C-N 3.32Å; D648-R650 PolarHBondContact O-N 3.09Å; D648-R650 VanDerWaalsContact O-N 3.15Å
651Q39.5Very low35.6Very low134 Ų134124.9 Ų124.963%0.62665%0.647SS**SBendtrans-85.4-14.4-176.3-73.9-178.2-0.600115.2N653Q651-N653 PolarHBondContact O-N 3.46Å
652L39.8Very low35.5Very low69 Ų69124.2 Ų124.236%0.36164%0.644SS.*G310 helixtrans-79.1-17.2-168.6-83.5141000114.9L629 M655L629-L652 HydrophobicContact CD1-CD1 4.26Å; L652-M655 HydrophobicContact CD2-CE 3.81Å; L652-M655 HydrophobicContact CG-CE 4.49Å
653N32Very low35.7Very low158 Ų158122.6 Ų122.685%0.84564%0.643SS**G310 helixtrans-84.5-4.6-178-72.8-4000114.1Q651Q651-N653 PolarHBondContact O-N 3.46Å
654A40.2Very low35.8Very low77 Ų77122.7 Ų122.764%0.63664%0.643SS**G310 helixtrans-102.7-1-173.300000115.4T656A654-T656 VanDerWaalsContact C-N 3.26Å; A654-T656 PolarHBondContact O-N 3.22Å
655M46.5Very low36Very low36 Ų36115.7 Ų115.718%0.17764%0.637CS.*  trans-8651.5-175.7-70.9-173.5-79.900113.1W623 K624 L652W623-M655 HydrophobicContact CZ3-SD 4.25Å; K624-M655 HydrophobicContact CD-CE 4.28Å; K624-M655 WeakPolarHBondContact CE-O 3.37Å; K624-M655 HydrophobicContact CG-CE 4.06Å; K624-M655 HydrophobicContact CG-SD 4.38Å; K624-M655 VanDerWaalsContact NZ-CB 3.34Å; K624-M655 PolarHBondContact NZ-O 3.48Å; L652-M655 HydrophobicContact CD2-CE 3.81Å; L652-M655 HydrophobicContact CG-CE 4.49Å
656T42.1Very low36.1Very low95 Ų95114.9 Ų114.958%0.58364%0.638SS**SBendtrans-112.8139.6170.145.40000108.7A654A654-T656 VanDerWaalsContact C-N 3.26Å; A654-T656 PolarHBondContact O-N 3.22Å
657L36.2Very low35.8Very low18 Ų18113 Ų1139%0.09464%0.639CS.*  trans-54.6142.2168.5-71.8172.6000108.8L613 K617 L620 D659 W710 A713L613-L657 WeakPolarHBondContact O-CD1 3.35Å; K617-L657 HydrophobicContact CB-CD1 3.83Å; K617-L657 HydrophobicContact CG-CD1 4.47Å; L620-L657 HydrophobicContact CD1-CD2 4.37Å; L620-L657 HydrophobicContact CD1-CG 4.31Å; L657-D659 PolarHBondContact O-N 3.08Å; L657-D659 VanDerWaalsContact O-N 3.12Å; L657-W710 HydrophobicContact CD2-CE3 4.45Å; L657-W710 HydrophobicContact CD2-CZ3 3.85Å; L657-A713 HydrophobicContact CD2-CB 4.04Å
658P41.2Very low36Very low36 Ų36112.1 Ų112.123%0.23464%0.636CS.*  trans-59.8117.3-179.9-1930000110.8F660 A728P658-F660 HydrophobicContact CB-CD2 3.83Å; P658-F660 HydrophobicContact CB-CE2 3.4Å; P658-F660 VanDerWaalsContact CB-CE2 3.4Å; P658-F660 HydrophobicContact CB-CZ 4.33Å; P658-A728 HydrophobicContact CG-CB 4.25Å
659D36.4Very low36.2Very low130 Ų130112.3 Ų112.370%0.69564%0.641SS**  trans-93.7113.3-179.8-135.6-10.5000108.8L657L657-D659 PolarHBondContact O-N 3.08Å; L657-D659 VanDerWaalsContact O-N 3.12Å
660F47.1Very low36.2Very low147 Ų147110 Ų11065%0.64564%0.638SS**  trans-134.644.5-176.8-67.2-68.1000112.7P658 E725P658-F660 HydrophobicContact CB-CD2 3.83Å; P658-F660 HydrophobicContact CB-CE2 3.4Å; P658-F660 VanDerWaalsContact CB-CE2 3.4Å; P658-F660 HydrophobicContact CB-CZ 4.33Å; F660-E725 HydrophobicContact CD2-CG 4.29Å
661S34.9Very low36Very low88 Ų88103.5 Ų103.562%0.61563%0.633SS**  trans-10190.6169.453.20000110.6
662D29.1Very low35.8Very low152 Ų152103 Ų10381%0.81364%0.639SS**  trans-170.7107145.2-101.6-22.7000112
663P36.8Very low35.8Very low124 Ų124102.9 Ų102.981%0.80564%0.644SS**  trans-93.9-1.5167.2-4.324000114.7
664D31Very low36.1Very low155 Ų155100 Ų10083%0.82963%0.627SS**  trans-110.170-171.4-80.8-26000113.3
665A32.2Very low35.9Very low95 Ų9599.2 Ų99.279%0.78562%0.621SS**  trans-145.491.415400000109S667A665-S667 PolarHBondContact O-N 3.42Å
666G30.4Very low35.3Very low80 Ų80100 Ų10083%0.82563%0.634SS**  trans-61.5122.4178.200000112.5
667S26.5Very low35.1Very low121 Ų12198.3 Ų98.385%0.84663%0.626SS**  173.7154120.557.90000110.4A665A665-S667 PolarHBondContact O-N 3.42Å
668S37Very low35.2Very low106 Ų106105.3 Ų105.374%0.74165%0.651SS**  trans-72.2163.7-159.848.90000115.6
669V32.9Very low35.1Very low124 Ų124107.7 Ų107.775%0.75267%0.665SS**SBendtrans101.6-8.3156-165.20000118.8
670H31.8Very low35.2Very low139 Ų139108.2 Ų108.264%0.64466%0.663SS**  trans-116.54.8178.6-82.7-31.8000118.2T672 S673 I674H670-T672 VanDerWaalsContact C-N 3.33Å; H670-T672 PolarHBondContact O-N 3.26Å; H670-S673 PolarHBondContact O-N 3.08Å; H670-S673 VanDerWaalsContact O-N 3.12Å; H670-I674 PolarHBondContact O-N 3.01Å
671A33.3Very low34.8Very low90 Ų90106.2 Ų106.274%0.74466%0.656SS**Hα-helixtrans-65.2-26.5-174.900000115.3
672T34.6Very low34.9Very low122 Ų122104.4 Ų104.475%0.74865%0.646SS**Hα-helixtrans-82.7-18.7175.7450000113.4H670 A676H670-T672 VanDerWaalsContact C-N 3.33Å; H670-T672 PolarHBondContact O-N 3.26Å; T672-A676 WeakPolarHBondContact O-CB 3.36Å
673S39.9Very low35.1Very low67 Ų67102.4 Ų102.447%0.46963%0.634SS.*Hα-helixtrans-85.2-35.1-176.9-174.40000112.5H670 S677H670-S673 PolarHBondContact O-N 3.08Å; H670-S673 VanDerWaalsContact O-N 3.12Å; S673-S677 WeakPolarHBondContact O-CB 3.37Å; S673-S677 PolarHBondContact O-N 3.4Å
674I37.1Very low35Very low97 Ų97100.5 Ų100.550%0.49762%0.624SS.*Hα-helixtrans-81.6-36.8-176-61.3172.8000111.9H670 R678H670-I674 PolarHBondContact O-N 3.01Å; I674-R678 WeakPolarHBondContact O-CB 3.44Å; I674-R678 WeakPolarHBondContact O-CG 3.34Å; I674-R678 PolarHBondContact O-N 3.46Å
675A36.4Very low35.4Very low61 Ų6198.8 Ų98.850%0.50461%0.611SS.*Hα-helixtrans-68.2-40.9173.300000111.4V679A675-V679 WeakPolarHBondContact O-CB 3.47Å; A675-V679 WeakPolarHBondContact O-CG2 3.37Å; A675-V679 PolarHBondContact O-N 2.91Å
676A34.8Very low35.6Very low53 Ų5397.6 Ų97.644%0.43859%0.594SS.*Hα-helixtrans-67.6-39.2173.900000112.2T672 V679 E680T672-A676 WeakPolarHBondContact O-CB 3.36Å; A676-V679 PolarHBondContact O-N 3.45Å; A676-E680 WeakPolarHBondContact O-CB 3.34Å; A676-E680 PolarHBondContact O-N 2.88Å
677S36.7Very low35.6Very low60 Ų6096.4 Ų96.442%0.4258%0.577SS.*Hα-helixtrans-65.8-39.5175.6169.60000112.5S673 E680 Q681S673-S677 WeakPolarHBondContact O-CB 3.37Å; S673-S677 PolarHBondContact O-N 3.4Å; S677-E680 PolarHBondContact O-N 3.26Å; S677-Q681 WeakPolarHBondContact O-CB 3.49Å; S677-Q681 PolarHBondContact O-N 2.93Å
678R40.1Very low35.9Very low165 Ų16594.5 Ų94.562%0.62356%0.563SS**Hα-helixtrans-73.5-30.5175.4-73.6-175.6179.9-173.31.4112.8I674 A682I674-R678 WeakPolarHBondContact O-CB 3.44Å; I674-R678 WeakPolarHBondContact O-CG 3.34Å; I674-R678 PolarHBondContact O-N 3.46Å; R678-A682 WeakPolarHBondContact O-CB 2.91Å; R678-A682 PolarHBondContact O-N 3.35Å
679V38Very low35.9Very low86 Ų8692.7 Ų92.752%0.52155%0.551SS.*Hα-helixtrans-72.2-39.9171.6170.40000110.9A675 A676 A682 L683A675-V679 WeakPolarHBondContact O-CB 3.47Å; A675-V679 WeakPolarHBondContact O-CG2 3.37Å; A675-V679 PolarHBondContact O-N 2.91Å; A676-V679 PolarHBondContact O-N 3.45Å; V679-A682 PolarHBondContact O-N 3Å; V679-L683 HydrophobicContact CG1-CD1 3.65Å; V679-L683 HydrophobicContact CG1-CG 4.28Å; V679-L683 WeakPolarHBondContact O-CB 3.31Å; V679-L683 WeakPolarHBondContact O-CD1 3.39Å; V679-L683 WeakPolarHBondContact O-CG 3.3Å; V679-L683 PolarHBondContact O-N 2.96Å
680E38.4Very low36Very low140 Ų14093.2 Ų93.265%0.65455%0.548SS*.Hα-helixtrans-67.4-34172.5-86.4-166.5158.200113.1A676 S677 S684A676-E680 WeakPolarHBondContact O-CB 3.34Å; A676-E680 PolarHBondContact O-N 2.88Å; S677-E680 PolarHBondContact O-N 3.26Å; E680-S684 VanDerWaalsContact O-CB 3.23Å; E680-S684 WeakPolarHBondContact O-CB 3.31Å; E680-S684 PolarHBondContact O-N 3.08Å; E680-S684 PolarHBondContact O-OG 3.04Å
681Q39Very low36Very low106 Ų10695 Ų9550%0.49556%0.557SS.*Hα-helixtrans-73.9-40.9176.2-158.7169.59.900111S677 S684 E685S677-Q681 WeakPolarHBondContact O-CB 3.49Å; S677-Q681 PolarHBondContact O-N 2.93Å; Q681-S684 PolarHBondContact O-N 2.96Å; Q681-E685 VanDerWaalsContact O-CB 3.31Å; Q681-E685 WeakPolarHBondContact O-CB 3.11Å; Q681-E685 VanDerWaalsContact O-CG 3.28Å; Q681-E685 WeakPolarHBondContact O-CG 3.5Å; Q681-E685 PolarHBondContact O-N 2.93Å
682A36.2Very low36Very low49 Ų4994.8 Ų94.841%0.40555%0.55SS..Hα-helixtrans-64.5-38.6169.800000112.1R678 V679 V686R678-A682 WeakPolarHBondContact O-CB 2.91Å; R678-A682 PolarHBondContact O-N 3.35Å; V679-A682 PolarHBondContact O-N 3Å; A682-V686 WeakPolarHBondContact O-CB 3.45Å; A682-V686 WeakPolarHBondContact O-CG2 3.39Å; A682-V686 PolarHBondContact O-N 3.22Å
683L34.1Very low35.8Very low110 Ų11094.7 Ų94.758%0.57655%0.554SS**Hα-helixtrans-72.2-33.9176.4-72.8167.3000112.5V679 A687V679-L683 HydrophobicContact CG1-CD1 3.65Å; V679-L683 HydrophobicContact CG1-CG 4.28Å; V679-L683 WeakPolarHBondContact O-CB 3.31Å; V679-L683 WeakPolarHBondContact O-CD1 3.39Å; V679-L683 WeakPolarHBondContact O-CG 3.3Å; V679-L683 PolarHBondContact O-N 2.96Å; L683-A687 WeakPolarHBondContact O-CB 3.41Å; L683-A687 PolarHBondContact O-N 3.33Å
684S34.1Very low35.4Very low85 Ų8594.7 Ų94.759%0.59456%0.559SS**Hα-helixtrans-72.8-35173.3-73.40000112.9E680 Q681 A687 S688E680-S684 VanDerWaalsContact O-CB 3.23Å; E680-S684 WeakPolarHBondContact O-CB 3.31Å; E680-S684 PolarHBondContact O-N 3.08Å; E680-S684 PolarHBondContact O-OG 3.04Å; Q681-S684 PolarHBondContact O-N 2.96Å; S684-A687 PolarHBondContact O-N 3.19Å; S684-S688 PolarHBondContact O-N 3.35Å
685E39.9Very low35.3Very low119 Ų11995.1 Ų95.156%0.55657%0.567SS**Hα-helixtrans-74.8-33.5173.5-73174.2-178.400111.6Q681 S688 S689Q681-E685 VanDerWaalsContact O-CB 3.31Å; Q681-E685 WeakPolarHBondContact O-CB 3.11Å; Q681-E685 VanDerWaalsContact O-CG 3.28Å; Q681-E685 WeakPolarHBondContact O-CG 3.5Å; Q681-E685 PolarHBondContact O-N 2.93Å; E685-S688 PolarHBondContact O-N 3.35Å; E685-S688 VanDerWaalsContact O-N 3.16Å; E685-S688 PolarHBondContact O-OG 3.41Å; E685-S689 PolarHBondContact O-N 3.04Å
686V35.9Very low35.6Very low69 Ų6997.4 Ų97.442%0.41857%0.566SS.*Hα-helixtrans-64.7-36.6168.7166.50000111.8A682 S688 S689 L690A682-V686 WeakPolarHBondContact O-CB 3.45Å; A682-V686 WeakPolarHBondContact O-CG2 3.39Å; A682-V686 PolarHBondContact O-N 3.22Å; V686-S688 PolarHBondContact O-N 2.96Å; V686-S689 WeakPolarHBondContact CA-OG 3.45Å; V686-S689 PolarHBondContact O-N 3.01Å; V686-S689 PolarHBondContact O-OG 2.99Å; V686-S689 VanDerWaalsContact O-OG 3.06Å; V686-L690 HydrophobicContact CG1-CD1 4.1Å; V686-L690 HydrophobicContact CG1-CG 4.4Å; V686-L690 WeakPolarHBondContact O-CB 3.33Å; V686-L690 WeakPolarHBondContact O-CD1 3.38Å; V686-L690 VanDerWaalsContact O-CG 3.24Å; V686-L690 WeakPolarHBondContact O-CG 3.33Å; V686-L690 PolarHBondContact O-N 3.26Å
687A31.6Very low35.6Very low56 Ų56103.8 Ų103.846%0.46359%0.586SS.*Hα-helixtrans-62.4-29.8172.100000112.8L683 S684L683-A687 WeakPolarHBondContact O-CB 3.41Å; L683-A687 PolarHBondContact O-N 3.33Å; S684-A687 PolarHBondContact O-N 3.19Å
688S32.1Very low36.1Very low80 Ų80103 Ų10356%0.55959%0.587SS**Hα-helixtrans-82.2-27.3175.277.20000113.8S684 E685 V686S684-S688 PolarHBondContact O-N 3.35Å; E685-S688 PolarHBondContact O-N 3.35Å; E685-S688 VanDerWaalsContact O-N 3.16Å; E685-S688 PolarHBondContact O-OG 3.41Å; V686-S688 PolarHBondContact O-N 2.96Å
689S37.2Very low36.9Very low69 Ų6999.3 Ų99.348%0.48359%0.585SS.*Hα-helixtrans-83.2-22.2176.4680000113.5E685 V686 Q691 S692E685-S689 PolarHBondContact O-N 3.04Å; V686-S689 WeakPolarHBondContact CA-OG 3.45Å; V686-S689 PolarHBondContact O-N 3.01Å; V686-S689 PolarHBondContact O-OG 2.99Å; V686-S689 VanDerWaalsContact O-OG 3.06Å; S689-Q691 PolarHBondContact O-N 3.29Å; S689-Q691 VanDerWaalsContact O-N 3.13Å; S689-S692 PolarHBondContact O-N 3.38Å; S689-S692 VanDerWaalsContact O-N 3.14Å
690L34.5Very low38.3Very low134 Ų13499.7 Ų99.770%0.70259%0.59SS**THydrogen-bonded Turntrans-61.5-14.2172.3-81163.2000113.9V686V686-L690 HydrophobicContact CG1-CD1 4.1Å; V686-L690 HydrophobicContact CG1-CG 4.4Å; V686-L690 WeakPolarHBondContact O-CB 3.33Å; V686-L690 WeakPolarHBondContact O-CD1 3.38Å; V686-L690 VanDerWaalsContact O-CG 3.24Å; V686-L690 WeakPolarHBondContact O-CG 3.33Å; V686-L690 PolarHBondContact O-N 3.26Å
691Q31.2Very low40Very low177 Ų17799.2 Ų99.283%0.82759%0.587SS**THydrogen-bonded Turntrans-88.6-5.6176-80.5176.4-14.200114.6S689S689-Q691 PolarHBondContact O-N 3.29Å; S689-Q691 VanDerWaalsContact O-N 3.13Å
692S35Very low41.9Very low85 Ų8594.7 Ų94.759%0.59457%0.567SS**  trans-111.462.6-180169.40000111.2S689 A694S689-S692 PolarHBondContact O-N 3.38Å; S689-S692 VanDerWaalsContact O-N 3.14Å; S692-A694 PolarHBondContact O-N 3.27Å
693S30.6Very low44.1Very low120 Ų12095.7 Ų95.784%0.83956%0.56SS**  trans-7554.1168.562.70000111.7
694A30.3Very low46.5Very low68 Ų6894.7 Ų94.756%0.56256%0.555SS**  trans-113.4125.7174.700000109.5S692 K696S692-A694 PolarHBondContact O-N 3.27Å; A694-K696 PolarHBondContact O-N 3.16Å
695P36.2Very low49Very low105 Ų10590.8 Ų90.868%0.68253%0.527SS*.  trans-64.3127177.126-31.5000109.6H697P695-H697 PolarHBondContact O-N 3.37Å; P695-H697 VanDerWaalsContact O-N 3.08Å
696K42.8Very low51.3Low109 Ų10985.4 Ų85.447%0.47450%0.502SS..  trans-62.8109.6178.9-67.6177.8176.4-179.50109.2A694 G698 W703A694-K696 PolarHBondContact O-N 3.16Å; K696-G698 PolarHBondContact O-N 3.28Å; K696-W703 HydrophobicContact CB-CZ2 4.45Å; K696-W703 HydrophobicContact CD-CH2 4.32Å
697H34.6Very low53.8Low187 Ų18782.4 Ų82.487%0.86649%0.485SS*.  trans-71.8119177.4-76.4-76.2000110.6P695P695-H697 PolarHBondContact O-N 3.37Å; P695-H697 VanDerWaalsContact O-N 3.08Å
698G46.4Very low56.7Low43 Ų4383.3 Ų83.344%0.44348%0.48SS..SBendtrans176.6167.8174.700000110.4K696K696-G698 PolarHBondContact O-N 3.28Å
699P55.9Low59.5Low89 Ų8979.5 Ų79.558%0.57845%0.453SS*.  trans-53.8137.8174.321.4-31.1000109.8H701 P702P699-H701 VanDerWaalsContact C-N 3.33Å; P699-H701 PolarHBondContact O-N 2.81Å; P699-P702 HydrophobicContact CB-CG 4.49Å; P699-P702 HydrophobicContact CG-CG 4Å; P699-P702 WeakPolarHBondContact O-CD 3.4Å
700P67.4Low62Low94 Ų9476.7 Ų76.761%0.6143%0.432SS*.Hα-helixtrans-68.1-35.2-174.425-33.1000111.8W703 L704P700-W703 PolarHBondContact O-N 2.99Å; P700-W703 VanDerWaalsContact O-N 3.13Å; P700-L704 HydrophobicContact CB-CD1 3.93Å; P700-L704 WeakPolarHBondContact O-CD1 3.46Å; P700-L704 PolarHBondContact O-N 3.42Å
701H74.6Confident64.8Low130 Ų13071 Ų7160%0.60240%0.402SS*.Hα-helixtrans-55.9-49.5-172.2178.6-80.6000113.9P699 W703 L704 T705P699-H701 VanDerWaalsContact C-N 3.33Å; P699-H701 PolarHBondContact O-N 2.81Å; H701-W703 VanDerWaalsContact C-N 3.31Å; H701-W703 PolarHBondContact O-N 3.35Å; H701-L704 WeakPolarHBondContact O-CB 3.47Å; H701-L704 PolarHBondContact O-N 3.43Å; H701-L704 VanDerWaalsContact O-N 3.16Å; H701-T705 PolarHBondContact O-N 3.03Å; H701-T705 PolarHBondContact O-OG1 3.01Å; H701-T705 VanDerWaalsContact O-OG1 3.04Å
702P79.7Confident67.8Low10 Ų1064.1 Ų64.17%0.06537%0.369CS..Hα-helixtrans-55.6-40.6175.8-30.938.4000114.6W623 Y627 P699 T705 L706W623-P702 PolarHBondContact NE1-O 3.45Å; Y627-P702 HydrophobicContact CD1-CB 3.76Å; Y627-P702 HydrophobicContact CD1-CG 3.79Å; Y627-P702 HydrophobicContact CD2-CB 4.06Å; Y627-P702 HydrophobicContact CE1-CB 3.54Å; Y627-P702 HydrophobicContact CE1-CG 3.22Å; Y627-P702 HydrophobicContact CE2-CB 3.86Å; Y627-P702 HydrophobicContact CE2-CG 4.32Å; Y627-P702 HydrophobicContact CG-CB 4.02Å; P699-P702 HydrophobicContact CB-CG 4.49Å; P699-P702 HydrophobicContact CG-CG 4Å; P699-P702 WeakPolarHBondContact O-CD 3.4Å; P702-T705 WeakPolarHBondContact O-CB 3.44Å; P702-T705 PolarHBondContact O-N 2.84Å; P702-L706 PolarHBondContact O-N 2.9Å
703W81.4Confident70.5Confident71 Ų7160.1 Ų60.127%0.26934%0.342SS..Hα-helixtrans-70.7-36.6179-58.7113.5000111.9W623 K696 P700 H701 L706 A707 L736W623-W703 HydrophobicContact CH2-CE3 4.21Å; W623-W703 HydrophobicContact CH2-CH2 4.29Å; W623-W703 AromaticContact CH2-CZ3 3.74Å; W623-W703 HydrophobicContact CH2-CZ3 3.74Å; W623-W703 AromaticContact CZ2-CE3 3.99Å; W623-W703 HydrophobicContact CZ2-CE3 3.99Å; W623-W703 HydrophobicContact CZ2-CZ3 4.01Å; K696-W703 HydrophobicContact CB-CZ2 4.45Å; K696-W703 HydrophobicContact CD-CH2 4.32Å; P700-W703 PolarHBondContact O-N 2.99Å; P700-W703 VanDerWaalsContact O-N 3.13Å; H701-W703 VanDerWaalsContact C-N 3.31Å; H701-W703 PolarHBondContact O-N 3.35Å; W703-L706 HydrophobicContact CE3-CD2 4.42Å; W703-L706 HydrophobicContact CZ3-CD2 4.48Å; W703-L706 PolarHBondContact O-N 3.47Å; W703-A707 WeakPolarHBondContact O-CB 3.35Å; W703-A707 PolarHBondContact O-N 3.47Å; W703-L736 HydrophobicContact CE3-CD2 3.85Å; W703-L736 HydrophobicContact CZ3-CD2 4.17Å
704L85.4Confident73.5Confident88 Ų8854.4 Ų54.446%0.46130%0.302SS..Hα-helixtrans-62.7-43.3171-84.893.7000111.4P700 H701 A707 Q708P700-L704 HydrophobicContact CB-CD1 3.93Å; P700-L704 WeakPolarHBondContact O-CD1 3.46Å; P700-L704 PolarHBondContact O-N 3.42Å; H701-L704 WeakPolarHBondContact O-CB 3.47Å; H701-L704 PolarHBondContact O-N 3.43Å; H701-L704 VanDerWaalsContact O-N 3.16Å; L704-A707 PolarHBondContact O-N 2.6Å; L704-Q708 WeakPolarHBondContact O-CB 3.37Å; L704-Q708 VanDerWaalsContact O-CG 3.32Å; L704-Q708 WeakPolarHBondContact O-CG 3.35Å; L704-Q708 PolarHBondContact O-N 2.75Å
705T87.2Confident76.5Confident3 Ų353.3 Ų53.32%0.01829%0.285CS..Hα-helixtrans-59.5-46.4175-53.50000110.9F593 Y597 H701 P702 A707 Q708 I709F593-T705 HydrophobicContact CB-CG2 4.11Å; F593-T705 HydrophobicContact CD1-CG2 3.54Å; F593-T705 HydrophobicContact CD2-CG2 3.79Å; F593-T705 HydrophobicContact CE1-CG2 3.85Å; F593-T705 HydrophobicContact CE2-CG2 4.06Å; F593-T705 HydrophobicContact CG-CG2 3.52Å; F593-T705 HydrophobicContact CZ-CG2 4.09Å; Y597-T705 WeakPolarHBondContact OH-CG2 3.49Å; Y597-T705 PolarHBondContact OH-O 3.41Å; H701-T705 PolarHBondContact O-N 3.03Å; H701-T705 PolarHBondContact O-OG1 3.01Å; H701-T705 VanDerWaalsContact O-OG1 3.04Å; P702-T705 WeakPolarHBondContact O-CB 3.44Å; P702-T705 PolarHBondContact O-N 2.84Å; T705-A707 PolarHBondContact O-N 3.31Å; T705-Q708 WeakPolarHBondContact O-CB 3.48Å; T705-Q708 PolarHBondContact O-N 2.63Å; T705-I709 HydrophobicContact CG2-CD1 4.32Å; T705-I709 VanDerWaalsContact O-CG1 3.32Å; T705-I709 WeakPolarHBondContact O-CG1 3.19Å; T705-I709 PolarHBondContact O-N 3.12Å
706L87.7Confident79.2Confident6 Ų649 Ų493%0.03126%0.257CS..Hα-helixtrans-61.4-44.7177.8-17559.4000112.1L620 W623 P702 W703 Q708 I709 W710 L736L620-L706 HydrophobicContact CD2-CD1 3.45Å; L620-L706 VanDerWaalsContact CD2-CD1 3.45Å; W623-L706 HydrophobicContact CD2-CB 4.19Å; W623-L706 HydrophobicContact CD2-CD1 3.9Å; W623-L706 HydrophobicContact CD2-CD2 4.25Å; W623-L706 HydrophobicContact CD2-CG 4.33Å; W623-L706 HydrophobicContact CE3-CD1 4.07Å; W623-L706 HydrophobicContact CE3-CD2 4.16Å; W623-L706 HydrophobicContact CG-CB 4.48Å; W623-L706 HydrophobicContact CG-CD1 4.18Å; W623-L706 HydrophobicContact CH2-CD2 3.65Å; W623-L706 HydrophobicContact CZ2-CB 4Å; W623-L706 HydrophobicContact CZ2-CD2 3.71Å; W623-L706 HydrophobicContact CZ2-CG 4.35Å; W623-L706 HydrophobicContact CZ3-CD2 3.88Å; P702-L706 PolarHBondContact O-N 2.9Å; W703-L706 HydrophobicContact CE3-CD2 4.42Å; W703-L706 HydrophobicContact CZ3-CD2 4.48Å; W703-L706 PolarHBondContact O-N 3.47Å; L706-Q708 VanDerWaalsContact C-N 3.3Å; L706-Q708 PolarHBondContact O-N 2.76Å; L706-I709 PolarHBondContact O-N 3.27Å; L706-W710 PolarHBondContact O-N 3.26Å; L706-W710 VanDerWaalsContact O-N 3.14Å; L706-L736 HydrophobicContact CB-CD1 3.88Å; L706-L736 HydrophobicContact CD2-CD1 3.54Å; L706-L736 HydrophobicContact CD2-CD2 4.16Å; L706-L736 HydrophobicContact CD2-CG 4.49Å; L706-L736 HydrophobicContact CG-CD1 3.5Å
707A88.9Confident81.5Confident6 Ų644.6 Ų44.65%0.0524%0.237CC..Hα-helixtrans-59.8-42.4175.400000111.2W703 L704 T705 W710 L711 L736W703-A707 WeakPolarHBondContact O-CB 3.35Å; W703-A707 PolarHBondContact O-N 3.47Å; L704-A707 PolarHBondContact O-N 2.6Å; T705-A707 PolarHBondContact O-N 3.31Å; A707-W710 PolarHBondContact O-N 3.22Å; A707-L711 WeakPolarHBondContact O-CG 3.39Å; A707-L711 PolarHBondContact O-N 3.16Å; A707-L736 HydrophobicContact CB-CB 4.35Å; A707-L736 HydrophobicContact CB-CD1 4.27Å
708Q90.9Very high84.3Confident76 Ų7637 Ų3736%0.35520%0.203SC..Hα-helixtrans-61.7-41.9175.8-76173.4-17.700112.7Y597 L704 T705 L706 W710 L711 H712Y597-Q708 HydrophobicContact CE1-CB 4.19Å; Y597-Q708 VanDerWaalsContact OH-CB 3.25Å; Y597-Q708 WeakPolarHBondContact OH-CB 3.49Å; Y597-Q708 PolarHBondContact OH-OE1 3.18Å; L704-Q708 WeakPolarHBondContact O-CB 3.37Å; L704-Q708 VanDerWaalsContact O-CG 3.32Å; L704-Q708 WeakPolarHBondContact O-CG 3.35Å; L704-Q708 PolarHBondContact O-N 2.75Å; T705-Q708 WeakPolarHBondContact O-CB 3.48Å; T705-Q708 PolarHBondContact O-N 2.63Å; L706-Q708 VanDerWaalsContact C-N 3.3Å; L706-Q708 PolarHBondContact O-N 2.76Å; Q708-W710 VanDerWaalsContact C-N 3.34Å; Q708-W710 PolarHBondContact O-N 2.95Å; Q708-L711 PolarHBondContact O-N 3.43Å; Q708-H712 PolarHBondContact O-CD2 3.34Å; Q708-H712 PolarHBondContact O-N 2.86Å
709I91.1Very high86.4Confident0 Ų038 Ų380%021%0.213CC..Hα-helixtrans-58.3-47.8175.8-63162.8000110.5F593 Y597 M619 L620 W623 T705 L706 L711 H712 A713F593-I709 HydrophobicContact CD1-CD1 4.08Å; F593-I709 HydrophobicContact CD1-CG1 4.45Å; F593-I709 HydrophobicContact CE1-CD1 3.68Å; Y597-I709 HydrophobicContact CE1-CG1 4.15Å; M619-I709 HydrophobicContact CB-CD1 3.97Å; M619-I709 HydrophobicContact CB-CG1 4.04Å; M619-I709 HydrophobicContact CB-CG2 3.99Å; M619-I709 HydrophobicContact CE-CG1 4.07Å; L620-I709 HydrophobicContact CD2-CB 4.25Å; L620-I709 HydrophobicContact CD2-CD1 4.47Å; L620-I709 HydrophobicContact CD2-CG2 3.62Å; L620-I709 HydrophobicContact CG-CG2 3.75Å; W623-I709 HydrophobicContact CB-CD1 4.11Å; W623-I709 HydrophobicContact CG-CD1 4.44Å; T705-I709 HydrophobicContact CG2-CD1 4.32Å; T705-I709 VanDerWaalsContact O-CG1 3.32Å; T705-I709 WeakPolarHBondContact O-CG1 3.19Å; T705-I709 PolarHBondContact O-N 3.12Å; L706-I709 PolarHBondContact O-N 3.27Å; I709-L711 VanDerWaalsContact C-N 3.34Å; I709-L711 PolarHBondContact O-N 2.94Å; I709-H712 PolarHBondContact O-N 3.22Å; I709-A713 PolarHBondContact O-N 3.13Å
710W91.2Very high88.1Confident10 Ų1035.8 Ų35.84%0.03820%0.196CC..Hα-helixtrans-62.1-39.5177.1-75.4119.1000112.9L620 L657 L706 A707 Q708 A713 A714 C729 E732 A733L620-W710 HydrophobicContact CD1-CH2 3.98Å; L620-W710 HydrophobicContact CD1-CZ2 4.06Å; L620-W710 HydrophobicContact CD1-CZ3 4.36Å; L620-W710 HydrophobicContact CD2-CZ2 4.22Å; L657-W710 HydrophobicContact CD2-CE3 4.45Å; L657-W710 HydrophobicContact CD2-CZ3 3.85Å; L706-W710 PolarHBondContact O-N 3.26Å; L706-W710 VanDerWaalsContact O-N 3.14Å; A707-W710 PolarHBondContact O-N 3.22Å; Q708-W710 VanDerWaalsContact C-N 3.34Å; Q708-W710 PolarHBondContact O-N 2.95Å; W710-A713 PolarHBondContact O-N 3.22Å; W710-A714 WeakPolarHBondContact O-CB 3.46Å; W710-A714 PolarHBondContact O-N 3.36Å; W710-C729 HydrophobicContact CE3-CB 4.09Å; W710-E732 HydrophobicContact CD2-CB 3.72Å; W710-E732 HydrophobicContact CD2-CG 4.37Å; W710-E732 HydrophobicContact CE3-CB 4.17Å; W710-E732 HydrophobicContact CE3-CG 4.49Å; W710-E732 HydrophobicContact CG-CB 3.95Å; W710-E732 HydrophobicContact CH2-CG 4.27Å; W710-E732 HydrophobicContact CZ2-CB 4.23Å; W710-E732 HydrophobicContact CZ2-CG 4.16Å; W710-E732 HydrophobicContact CZ3-CG 4.42Å; W710-A733 HydrophobicContact CB-CB 3.99Å
711L93.3Very high89.3Confident14 Ų1435.3 Ų35.37%0.07319%0.194CC..Hα-helixtrans-67.7-37.2176.9-66.5172.3000112A707 Q708 I709 A714 E715 T730 A733 N742 M743 M746A707-L711 WeakPolarHBondContact O-CG 3.39Å; A707-L711 PolarHBondContact O-N 3.16Å; Q708-L711 PolarHBondContact O-N 3.43Å; I709-L711 VanDerWaalsContact C-N 3.34Å; I709-L711 PolarHBondContact O-N 2.94Å; L711-A714 PolarHBondContact O-N 2.73Å; L711-E715 PolarHBondContact O-N 3.4Å; L711-T730 HydrophobicContact CD2-CG2 4.41Å; L711-A733 HydrophobicContact CD2-CB 3.72Å; L711-A733 HydrophobicContact CG-CB 3.85Å; L711-N742 HydrophobicContact CD1-CB 3.73Å; L711-M743 HydrophobicContact CD2-CB 4.1Å; L711-M743 HydrophobicContact CD2-CG 4.48Å; L711-M746 HydrophobicContact CB-CG 4.49Å; L711-M746 HydrophobicContact CD2-CB 4.16Å; L711-M746 HydrophobicContact CD2-CG 3.64Å
712H92.8Very high90Very high32 Ų3232.8 Ų32.815%0.14818%0.182CC..Hα-helixtrans-65.3-42.5173.4-77.9-56.7000112.2Y597 Q708 I709 A714 E715 V716Y597-H712 AromaticContact CD1-CD2 3.18Å; Y597-H712 WeakPolarHBondContact CD1-CD2 3.48Å; Y597-H712 AromaticContact CD1-NE2 3.42Å; Y597-H712 WeakPolarHBondContact CD1-NE2 3.46Å; Y597-H712 AromaticContact CE1-CD2 3.5Å; Y597-H712 VanDerWaalsContact CE1-CD2 3.5Å; Y597-H712 WeakPolarHBondContact CE1-CD2 3.48Å; Y597-H712 AromaticContact CE1-NE2 3.93Å; Y597-H712 AromaticContact CG-CD2 3.92Å; Y597-H712 AromaticContact CG-NE2 3.64Å; Q708-H712 PolarHBondContact O-CD2 3.34Å; Q708-H712 PolarHBondContact O-N 2.86Å; I709-H712 PolarHBondContact O-N 3.22Å; H712-A714 VanDerWaalsContact C-N 3.35Å; H712-A714 PolarHBondContact O-N 2.7Å; H712-E715 IonicContact ND1-OE2 3.61Å; H712-E715 WeakPolarHBondContact O-CB 3.01Å; H712-E715 PolarHBondContact O-N 3.21Å; H712-V716 WeakPolarHBondContact O-CG2 3.44Å; H712-V716 PolarHBondContact O-N 3.13Å; H712-V716 VanDerWaalsContact O-N 3.15Å
713A91.4Very high90.5Very high1 Ų134.3 Ų34.31%0.00819%0.192CC..Hα-helixtrans-61.4-43.2173.300000111.8L613 C616 L657 I709 W710 E715 V716 Y717L613-A713 HydrophobicContact CD2-CB 4.29Å; C616-A713 HydrophobicContact CB-CB 4.19Å; L657-A713 HydrophobicContact CD2-CB 4.04Å; I709-A713 PolarHBondContact O-N 3.13Å; W710-A713 PolarHBondContact O-N 3.22Å; A713-E715 VanDerWaalsContact C-N 3.29Å; A713-E715 PolarHBondContact O-N 2.98Å; A713-V716 PolarHBondContact O-N 3.34Å; A713-Y717 VanDerWaalsContact O-CD2 3.23Å; A713-Y717 WeakPolarHBondContact O-CD2 3.45Å; A713-Y717 PolarHBondContact O-N 2.95Å
714A93.5Very high90.8Very high0 Ų034.1 Ų34.10%021%0.205CC..Hα-helixtrans-58.9-40.8175.100000112.2W710 L711 H712 V716 Y717 I718 C729 T730 M746W710-A714 WeakPolarHBondContact O-CB 3.46Å; W710-A714 PolarHBondContact O-N 3.36Å; L711-A714 PolarHBondContact O-N 2.73Å; H712-A714 VanDerWaalsContact C-N 3.35Å; H712-A714 PolarHBondContact O-N 2.7Å; A714-V716 VanDerWaalsContact C-N 3.33Å; A714-V716 PolarHBondContact O-N 3.02Å; A714-Y717 PolarHBondContact O-N 2.98Å; A714-I718 VanDerWaalsContact O-CG1 3.3Å; A714-I718 WeakPolarHBondContact O-CG1 3.18Å; A714-I718 PolarHBondContact O-N 3.2Å; A714-C729 HydrophobicContact CB-CB 3.79Å; A714-T730 HydrophobicContact CB-CG2 3.67Å; A714-M746 HydrophobicContact CB-CE 3.98Å
715E94.4Very high90.9Very high45 Ų4531.4 Ų31.421%0.2119%0.19CC..Hα-helixtrans-64-38.2178.8-161.4175.6176.800112.2K601 L711 H712 A713 I718 G719 M746K601-E715 WeakPolarHBondContact CE-OE2 3.45Å; K601-E715 IonicContact NZ-OE1 3.53Å; K601-E715 PolarHBondContact NZ-OE1 2.88Å; K601-E715 IonicContact NZ-OE2 3.65Å; K601-E715 PolarHBondContact NZ-OE2 3.19Å; L711-E715 PolarHBondContact O-N 3.4Å; H712-E715 IonicContact ND1-OE2 3.61Å; H712-E715 WeakPolarHBondContact O-CB 3.01Å; H712-E715 PolarHBondContact O-N 3.21Å; A713-E715 VanDerWaalsContact C-N 3.29Å; A713-E715 PolarHBondContact O-N 2.98Å; E715-I718 PolarHBondContact O-N 3.42Å; E715-G719 PolarHBondContact O-N 3.41Å; E715-G719 VanDerWaalsContact O-N 3.09Å; E715-M746 HydrophobicContact CB-CE 3.53Å; E715-M746 HydrophobicContact CG-CE 4.02Å; E715-M746 VanDerWaalsContact N-CE 3.32Å
716V93.1Very high90.9Very high15 Ų1531.2 Ų31.29%0.09119%0.189CC..Hα-helixtrans-65-45.5173.5-179.90000110.9V600 P609 A612 L613 H712 A713 A714 I718 G719 M720V600-V716 HydrophobicContact CG1-CG2 4.15Å; P609-V716 HydrophobicContact CB-CG1 3.58Å; P609-V716 WeakPolarHBondContact O-CG1 3.48Å; A612-V716 HydrophobicContact CB-CG1 4.36Å; A612-V716 HydrophobicContact CB-CG2 4.06Å; L613-V716 HydrophobicContact CD1-CG1 4.34Å; L613-V716 HydrophobicContact CD2-CB 4.05Å; L613-V716 HydrophobicContact CD2-CG1 4.05Å; L613-V716 HydrophobicContact CG-CB 4.36Å; L613-V716 HydrophobicContact CG-CG1 3.8Å; H712-V716 WeakPolarHBondContact O-CG2 3.44Å; H712-V716 PolarHBondContact O-N 3.13Å; H712-V716 VanDerWaalsContact O-N 3.15Å; A713-V716 PolarHBondContact O-N 3.34Å; A714-V716 VanDerWaalsContact C-N 3.33Å; A714-V716 PolarHBondContact O-N 3.02Å; V716-I718 VanDerWaalsContact C-N 3.32Å; V716-I718 PolarHBondContact O-N 3.12Å; V716-G719 WeakPolarHBondContact O-CA 3.19Å; V716-G719 PolarHBondContact O-N 3.11Å; V716-G719 VanDerWaalsContact O-N 3.08Å; V716-M720 HydrophobicContact CG1-SD 4.46Å; V716-M720 WeakPolarHBondContact O-CG 3.37Å; V716-M720 PolarHBondContact O-N 2.9Å
717Y91.5Very high91.1Very high16 Ų1633 Ų336%0.06320%0.2CC..Hα-helixtrans-63.3-34.4176.8-76.3-59.5000113.6L613 A713 A714 G719 M720 S721 K722 E725L613-Y717 HydrophobicContact CD1-CD1 4.2Å; L613-Y717 HydrophobicContact CD1-CE1 3.59Å; L613-Y717 HydrophobicContact CD1-CE2 4.44Å; L613-Y717 HydrophobicContact CD2-CD2 4.17Å; L613-Y717 HydrophobicContact CD2-CE1 4.36Å; L613-Y717 HydrophobicContact CD2-CE2 3.75Å; A713-Y717 VanDerWaalsContact O-CD2 3.23Å; A713-Y717 WeakPolarHBondContact O-CD2 3.45Å; A713-Y717 PolarHBondContact O-N 2.95Å; A714-Y717 PolarHBondContact O-N 2.98Å; Y717-G719 VanDerWaalsContact C-N 3.35Å; Y717-M720 HydrophobicContact CD1-SD 4.09Å; Y717-M720 HydrophobicContact CE1-SD 4.47Å; Y717-M720 CarbonylContact O-C 3.34Å; Y717-M720 PolarHBondContact O-N 3.49Å; Y717-S721 PolarHBondContact O-N 2.83Å; Y717-K722 HydrophobicContact CD1-CB 4.25Å; Y717-K722 HydrophobicContact CD1-CD 4.25Å; Y717-K722 PolarHBondContact O-N 2.92Å; Y717-E725 HydrophobicContact CD1-CB 3.64Å; Y717-E725 HydrophobicContact CD1-CG 4.33Å; Y717-E725 HydrophobicContact CD2-CB 3.93Å; Y717-E725 HydrophobicContact CE1-CB 3.78Å; Y717-E725 HydrophobicContact CE1-CG 4.16Å; Y717-E725 HydrophobicContact CE2-CB 4.06Å; Y717-E725 HydrophobicContact CG-CB 3.73Å
718I93Very high91Very high27 Ų2734.7 Ų34.714%0.13821%0.214CC..Hα-helixtrans-62.8-44171.8-69.6171.3000110.1A714 E715 V716 M720 S721 A726 M746 Q749 I750A714-I718 VanDerWaalsContact O-CG1 3.3Å; A714-I718 WeakPolarHBondContact O-CG1 3.18Å; A714-I718 PolarHBondContact O-N 3.2Å; E715-I718 PolarHBondContact O-N 3.42Å; V716-I718 VanDerWaalsContact C-N 3.32Å; V716-I718 PolarHBondContact O-N 3.12Å; I718-M720 PolarHBondContact O-N 3.02Å; I718-S721 PolarHBondContact O-N 2.98Å; I718-A726 HydrophobicContact CG1-CB 3.76Å; I718-M746 HydrophobicContact CD1-CE 3.51Å; I718-Q749 HydrophobicContact CD1-CB 3.75Å; I718-I750 HydrophobicContact CD1-CG1 3.77Å; I718-I750 HydrophobicContact CG1-CG1 4.02Å
719G90.6Very high90.8Very high65 Ų6531 Ų3167%0.6720%0.197SC*.Hα-helixtrans-59.4-33.2173.600000113.5E715 V716 Y717 S721E715-G719 PolarHBondContact O-N 3.41Å; E715-G719 VanDerWaalsContact O-N 3.09Å; V716-G719 WeakPolarHBondContact O-CA 3.19Å; V716-G719 PolarHBondContact O-N 3.11Å; V716-G719 VanDerWaalsContact O-N 3.08Å; Y717-G719 VanDerWaalsContact C-N 3.35Å; G719-S721 PolarHBondContact O-N 2.68Å
720M90.6Very high90.6Very high43 Ų4331.1 Ų31.121%0.21220%0.198CC..THydrogen-bonded Turntrans-78.2-0.3174.1-62.7176.382.500114.2P609 E610 L613 V716 Y717 I718 K722P609-M720 HydrophobicContact CB-CE 4.4Å; P609-M720 HydrophobicContact CB-CG 3.52Å; P609-M720 HydrophobicContact CB-SD 3.76Å; P609-M720 HydrophobicContact CG-CE 4.12Å; P609-M720 HydrophobicContact CG-CG 3.73Å; P609-M720 HydrophobicContact CG-SD 4.11Å; E610-M720 WeakPolarHBondContact OE1-CE 3.44Å; L613-M720 HydrophobicContact CD1-SD 3.89Å; V716-M720 HydrophobicContact CG1-SD 4.46Å; V716-M720 WeakPolarHBondContact O-CG 3.37Å; V716-M720 PolarHBondContact O-N 2.9Å; Y717-M720 HydrophobicContact CD1-SD 4.09Å; Y717-M720 HydrophobicContact CE1-SD 4.47Å; Y717-M720 CarbonylContact O-C 3.34Å; Y717-M720 PolarHBondContact O-N 3.49Å; I718-M720 PolarHBondContact O-N 3.02Å; M720-K722 VanDerWaalsContact C-N 3.26Å; M720-K722 HydrophobicContact CB-CB 4.43Å; M720-K722 HydrophobicContact CB-CD 4.27Å; M720-K722 HydrophobicContact CB-CG 4.17Å; M720-K722 HydrophobicContact CE-CD 4.26Å; M720-K722 PolarHBondContact O-N 2.87Å; M720-K722 HydrophobicContact SD-CD 4.49Å
721S92.6Very high90.5Very high83 Ų8334.5 Ų34.558%0.5821%0.214SC*.THydrogen-bonded Turntrans5834.6-172.7-56.10000114Y717 I718 G719 P723Y717-S721 PolarHBondContact O-N 2.83Å; I718-S721 PolarHBondContact O-N 2.98Å; G719-S721 PolarHBondContact O-N 2.68Å; S721-P723 WeakPolarHBondContact O-CD 3.39Å
722K89.9Confident90.1Very high77 Ų7737.7 Ų37.734%0.33523%0.229SC..  trans-108.282.4179.5-76.2-175176.7-175.40111.1Y717 M720 A724 E725 A726Y717-K722 HydrophobicContact CD1-CB 4.25Å; Y717-K722 HydrophobicContact CD1-CD 4.25Å; Y717-K722 PolarHBondContact O-N 2.92Å; M720-K722 VanDerWaalsContact C-N 3.26Å; M720-K722 HydrophobicContact CB-CB 4.43Å; M720-K722 HydrophobicContact CB-CD 4.27Å; M720-K722 HydrophobicContact CB-CG 4.17Å; M720-K722 HydrophobicContact CE-CD 4.26Å; M720-K722 PolarHBondContact O-N 2.87Å; M720-K722 HydrophobicContact SD-CD 4.49Å; K722-A724 PolarHBondContact O-N 2.74Å; K722-E725 WeakPolarHBondContact CB-OE2 2.93Å; K722-A726 PolarHBondContact O-N 2.93Å
723P90.5Very high89.8Confident42 Ų4236.2 Ų36.227%0.27322%0.222SC..Hα-helixtrans-71-24.6-171.527.2-35.2000114.3S721 T727 I750 L753 R754S721-P723 WeakPolarHBondContact O-CD 3.39Å; P723-T727 WeakPolarHBondContact O-CB 3.09Å; P723-T727 PolarHBondContact O-N 3.24Å; P723-T727 VanDerWaalsContact O-N 3.07Å; P723-T727 PolarHBondContact O-OG1 2.89Å; P723-I750 HydrophobicContact CB-CG2 4.4Å; P723-L753 HydrophobicContact CB-CD2 3.9Å; P723-L753 HydrophobicContact CB-CG 4.35Å; P723-L753 HydrophobicContact CG-CD2 4.42Å; P723-R754 HydrophobicContact CB-CG 4.17Å
724A87.9Confident89.6Confident67 Ų6736.5 Ų36.555%0.55422%0.224SC*.Hα-helixtrans-71.5-46.6-17800000111.3K722 T727 A728K722-A724 PolarHBondContact O-N 2.74Å; A724-T727 WeakPolarHBondContact O-CB 3.12Å; A724-T727 PolarHBondContact O-N 2.78Å; A724-T727 VanDerWaalsContact O-N 3.16Å; A724-A728 PolarHBondContact O-N 3.31Å
725E86.6Confident89.2Confident31 Ų3140.6 Ų40.615%0.14525%0.246CC..Hα-helixtrans-67.7-40.8178.7-61.591.2143.900111.3F660 Y717 K722 T727 A728 C729F660-E725 HydrophobicContact CD2-CG 4.29Å; Y717-E725 HydrophobicContact CD1-CB 3.64Å; Y717-E725 HydrophobicContact CD1-CG 4.33Å; Y717-E725 HydrophobicContact CD2-CB 3.93Å; Y717-E725 HydrophobicContact CE1-CB 3.78Å; Y717-E725 HydrophobicContact CE1-CG 4.16Å; Y717-E725 HydrophobicContact CE2-CB 4.06Å; Y717-E725 HydrophobicContact CG-CB 3.73Å; K722-E725 WeakPolarHBondContact CB-OE2 2.93Å; E725-T727 VanDerWaalsContact C-N 3.27Å; E725-T727 PolarHBondContact O-N 2.87Å; E725-A728 PolarHBondContact O-N 3.21Å; E725-C729 PolarHBondContact O-N 3.33Å; E725-C729 PolarHBondContact O-SG 2.91Å
726A88.6Confident88.6Confident0 Ų040 Ų400%024%0.244CC..Hα-helixtrans-60.5-37.4171.200000112I718 K722 C729 T730 I750I718-A726 HydrophobicContact CG1-CB 3.76Å; K722-A726 PolarHBondContact O-N 2.93Å; A726-C729 PolarHBondContact O-N 3.47Å; A726-T730 WeakPolarHBondContact O-CB 3.49Å; A726-T730 WeakPolarHBondContact O-CG2 3.48Å; A726-T730 PolarHBondContact O-N 3.47Å; A726-T730 PolarHBondContact O-OG1 2.89Å; A726-I750 HydrophobicContact CB-CD1 3.84Å; A726-I750 HydrophobicContact CB-CG1 3.86Å; A726-I750 WeakPolarHBondContact O-CD1 3.05Å
727T90.3Very high87.9Confident42 Ų4240.8 Ų40.826%0.25825%0.251SS..Hα-helixtrans-66.4-41.6176-55.20000111.4P723 A724 E725 T730 Q731 I750 R754P723-T727 WeakPolarHBondContact O-CB 3.09Å; P723-T727 PolarHBondContact O-N 3.24Å; P723-T727 VanDerWaalsContact O-N 3.07Å; P723-T727 PolarHBondContact O-OG1 2.89Å; A724-T727 WeakPolarHBondContact O-CB 3.12Å; A724-T727 PolarHBondContact O-N 2.78Å; A724-T727 VanDerWaalsContact O-N 3.16Å; E725-T727 VanDerWaalsContact C-N 3.27Å; E725-T727 PolarHBondContact O-N 2.87Å; T727-T730 WeakPolarHBondContact CA-OG1 3.4Å; T727-T730 PolarHBondContact O-N 2.78Å; T727-T730 PolarHBondContact O-OG1 2.88Å; T727-Q731 VanDerWaalsContact O-CB 3.29Å; T727-Q731 WeakPolarHBondContact O-CB 3.35Å; T727-Q731 PolarHBondContact O-N 3.27Å; T727-I750 WeakPolarHBondContact OG1-CG2 3.42Å; T727-R754 PolarHBondContact OG1-NH2 2.95Å
728A87.7Confident87.4Confident42 Ų4244.2 Ų44.235%0.34728%0.275SS..Hα-helixtrans-61.6-48.1176.100000111.4P658 A724 E725 T730 Q731 E732P658-A728 HydrophobicContact CG-CB 4.25Å; A724-A728 PolarHBondContact O-N 3.31Å; E725-A728 PolarHBondContact O-N 3.21Å; A728-T730 PolarHBondContact O-N 3.47Å; A728-Q731 WeakPolarHBondContact O-CB 3.49Å; A728-Q731 PolarHBondContact O-N 3.31Å; A728-E732 PolarHBondContact O-N 3.06Å
729C86Confident87Confident0 Ų048 Ų480%030%0.299CS..Hα-helixtrans-62.7-43178.7-64.10000112.3W710 A714 E725 A726 Q731 E732 A733W710-C729 HydrophobicContact CE3-CB 4.09Å; A714-C729 HydrophobicContact CB-CB 3.79Å; E725-C729 PolarHBondContact O-N 3.33Å; E725-C729 PolarHBondContact O-SG 2.91Å; A726-C729 PolarHBondContact O-N 3.47Å; C729-Q731 VanDerWaalsContact C-N 3.32Å; C729-Q731 PolarHBondContact O-N 3.41Å; C729-E732 PolarHBondContact O-N 2.87Å; C729-A733 PolarHBondContact O-N 2.97Å; C729-A733 VanDerWaalsContact O-N 3.08Å
730T88.1Confident86.9Confident2 Ų246.2 Ų46.21%0.01228%0.276CS..Hα-helixtrans-68.1-30.4175.950.80000112.9L711 A714 A726 T727 A728 A733 A734 M746 I750L711-T730 HydrophobicContact CD2-CG2 4.41Å; A714-T730 HydrophobicContact CB-CG2 3.67Å; A726-T730 WeakPolarHBondContact O-CB 3.49Å; A726-T730 WeakPolarHBondContact O-CG2 3.48Å; A726-T730 PolarHBondContact O-N 3.47Å; A726-T730 PolarHBondContact O-OG1 2.89Å; T727-T730 WeakPolarHBondContact CA-OG1 3.4Å; T727-T730 PolarHBondContact O-N 2.78Å; T727-T730 PolarHBondContact O-OG1 2.88Å; A728-T730 PolarHBondContact O-N 3.47Å; T730-A733 PolarHBondContact O-N 3.07Å; T730-A734 WeakPolarHBondContact O-CB 3.34Å; T730-A734 PolarHBondContact O-N 3.11Å; T730-M746 HydrophobicContact CG2-CB 3.48Å; T730-M746 VanDerWaalsContact CG2-CB 3.48Å; T730-M746 HydrophobicContact CG2-CG 4.38Å; T730-I750 HydrophobicContact CG2-CD1 3.64Å; T730-I750 WeakPolarHBondContact OG1-CD1 3.28Å
731Q88Confident86.9Confident80 Ų8046.1 Ų46.137%0.37428%0.275SS..Hα-helixtrans-66.8-40.4173.2-174.957.54100111.4T727 A728 C729 A734 N735T727-Q731 VanDerWaalsContact O-CB 3.29Å; T727-Q731 WeakPolarHBondContact O-CB 3.35Å; T727-Q731 PolarHBondContact O-N 3.27Å; A728-Q731 WeakPolarHBondContact O-CB 3.49Å; A728-Q731 PolarHBondContact O-N 3.31Å; C729-Q731 VanDerWaalsContact C-N 3.32Å; C729-Q731 PolarHBondContact O-N 3.41Å; Q731-A734 WeakPolarHBondContact O-CB 3.29Å; Q731-A734 PolarHBondContact O-N 3.42Å; Q731-N735 PolarHBondContact NE2-OD1 3.1Å; Q731-N735 PolarHBondContact O-N 2.91Å; Q731-N735 PolarHBondContact O-ND2 3.45Å; Q731-N735 PolarHBondContact O-OD1 3.3Å
732E86Confident86.8Confident82 Ų8244.8 Ų44.838%0.38326%0.262SS..Hα-helixtrans-62.9-43.3173.1-69.3-52.8140.300112.1W710 A728 C729 A734 N735 L736W710-E732 HydrophobicContact CD2-CB 3.72Å; W710-E732 HydrophobicContact CD2-CG 4.37Å; W710-E732 HydrophobicContact CE3-CB 4.17Å; W710-E732 HydrophobicContact CE3-CG 4.49Å; W710-E732 HydrophobicContact CG-CB 3.95Å; W710-E732 HydrophobicContact CH2-CG 4.27Å; W710-E732 HydrophobicContact CZ2-CB 4.23Å; W710-E732 HydrophobicContact CZ2-CG 4.16Å; W710-E732 HydrophobicContact CZ3-CG 4.42Å; A728-E732 PolarHBondContact O-N 3.06Å; C729-E732 PolarHBondContact O-N 2.87Å; E732-A734 VanDerWaalsContact C-N 3.3Å; E732-A734 PolarHBondContact O-N 3.32Å; E732-N735 WeakPolarHBondContact O-CB 3.23Å; E732-N735 PolarHBondContact O-N 3.49Å; E732-N735 PolarHBondContact OE2-ND2 2.86Å; E732-L736 WeakPolarHBondContact O-CG 3.49Å; E732-L736 PolarHBondContact O-N 3.44Å
733A85.6Confident87Confident1 Ų141.3 Ų41.31%0.00825%0.247CC..Hα-helixtrans-60.6-39.317200000112.3W710 L711 C729 T730 N735 L736 S737W710-A733 HydrophobicContact CB-CB 3.99Å; L711-A733 HydrophobicContact CD2-CB 3.72Å; L711-A733 HydrophobicContact CG-CB 3.85Å; C729-A733 PolarHBondContact O-N 2.97Å; C729-A733 VanDerWaalsContact O-N 3.08Å; T730-A733 PolarHBondContact O-N 3.07Å; A733-N735 VanDerWaalsContact C-N 3.35Å; A733-N735 PolarHBondContact O-N 2.66Å; A733-L736 PolarHBondContact O-N 3.27Å; A733-S737 PolarHBondContact O-N 3.44Å
734A87.3Confident87.1Confident7 Ų740.3 Ų40.36%0.05824%0.239CC..Hα-helixtrans-64.5-37.7177.600000112.2T730 Q731 E732 L736 S737 P738 M743T730-A734 WeakPolarHBondContact O-CB 3.34Å; T730-A734 PolarHBondContact O-N 3.11Å; Q731-A734 WeakPolarHBondContact O-CB 3.29Å; Q731-A734 PolarHBondContact O-N 3.42Å; E732-A734 VanDerWaalsContact C-N 3.3Å; E732-A734 PolarHBondContact O-N 3.32Å; A734-L736 PolarHBondContact O-N 3.03Å; A734-S737 CarbonylContact O-C 3.59Å; A734-S737 PolarHBondContact O-N 3.37Å; A734-P738 VanDerWaalsContact O-CA 3.3Å; A734-P738 WeakPolarHBondContact O-CA 3.3Å; A734-P738 WeakPolarHBondContact O-CD 3.36Å; A734-P738 WeakPolarHBondContact O-CG 3.5Å; A734-P738 VanDerWaalsContact O-N 3.08Å; A734-M743 HydrophobicContact CB-CG 4.11Å; A734-M743 HydrophobicContact CB-SD 3.4Å; A734-M743 WeakPolarHBondContact CB-SD 3.28Å
735N84.6Confident87.5Confident85 Ų8538 Ų3846%0.45522%0.216SC..Hα-helixtrans-62.5-25.4176.9-64.4-22.3000112.4Q731 E732 A733Q731-N735 PolarHBondContact NE2-OD1 3.1Å; Q731-N735 PolarHBondContact O-N 2.91Å; Q731-N735 PolarHBondContact O-ND2 3.45Å; Q731-N735 PolarHBondContact O-OD1 3.3Å; E732-N735 WeakPolarHBondContact O-CB 3.23Å; E732-N735 PolarHBondContact O-N 3.49Å; E732-N735 PolarHBondContact OE2-ND2 2.86Å; A733-N735 VanDerWaalsContact C-N 3.35Å; A733-N735 PolarHBondContact O-N 2.66Å
736L81.8Confident87.8Confident33 Ų3336.8 Ų36.817%0.17321%0.21CC..Hα-helixtrans-93.4-39.9-179.5-59.2172.1000112.6W703 L706 A707 E732 A733 A734W703-L736 HydrophobicContact CE3-CD2 3.85Å; W703-L736 HydrophobicContact CZ3-CD2 4.17Å; L706-L736 HydrophobicContact CB-CD1 3.88Å; L706-L736 HydrophobicContact CD2-CD1 3.54Å; L706-L736 HydrophobicContact CD2-CD2 4.16Å; L706-L736 HydrophobicContact CD2-CG 4.49Å; L706-L736 HydrophobicContact CG-CD1 3.5Å; A707-L736 HydrophobicContact CB-CB 4.35Å; A707-L736 HydrophobicContact CB-CD1 4.27Å; E732-L736 WeakPolarHBondContact O-CG 3.49Å; E732-L736 PolarHBondContact O-N 3.44Å; A733-L736 PolarHBondContact O-N 3.27Å; A734-L736 PolarHBondContact O-N 3.03Å
737S78.2Confident88.1Confident32 Ų3239.8 Ų39.822%0.22422%0.221CC..  trans-143.982179.6-77.70000110.5A733 A734 T739 S740A733-S737 PolarHBondContact O-N 3.44Å; A734-S737 CarbonylContact O-C 3.59Å; A734-S737 PolarHBondContact O-N 3.37Å; S737-T739 PolarHBondContact O-N 3Å; S737-S740 WeakPolarHBondContact O-CB 3.23Å; S737-S740 PolarHBondContact O-N 3.22Å; S737-S740 VanDerWaalsContact O-N 3.17Å
738P82Confident88.3Confident88 Ų8837.8 Ų37.857%0.57121%0.209SC*.THydrogen-bonded Turntrans-60.2-29.1-176.7-21.329.1000113.5A734A734-P738 VanDerWaalsContact O-CA 3.3Å; A734-P738 WeakPolarHBondContact O-CA 3.3Å; A734-P738 WeakPolarHBondContact O-CD 3.36Å; A734-P738 WeakPolarHBondContact O-CG 3.5Å; A734-P738 VanDerWaalsContact O-N 3.08Å
739T84.2Confident88.7Confident105 Ų10537.1 Ų37.164%0.64420%0.199SC*.THydrogen-bonded Turntrans-96.217.3-176.558.50000113.1S737S737-T739 PolarHBondContact O-N 3Å
740S87.4Confident89.1Confident28 Ų2837.4 Ų37.420%0.19620%0.2CC..  trans-78.5122.7-179.81790000111.8S737 N742 M743 M744S737-S740 WeakPolarHBondContact O-CB 3.23Å; S737-S740 PolarHBondContact O-N 3.22Å; S737-S740 VanDerWaalsContact O-N 3.17Å; S740-N742 PolarHBondContact O-N 3.16Å; S740-N742 PolarHBondContact OG-N 3.38Å; S740-M743 WeakPolarHBondContact O-CB 3.31Å; S740-M743 PolarHBondContact O-N 3.15Å; S740-M743 VanDerWaalsContact O-N 3.11Å; S740-M744 PolarHBondContact O-N 3.28Å; S740-M744 VanDerWaalsContact O-N 3.09Å
741H91.9Very high89.4Confident41 Ų4137.4 Ų37.419%0.1920%0.2CC..Hα-helixtrans-59.8-34.1175.168.1-86.6000112.6M743 M744 Y745 I770 N771 H774H741-M743 VanDerWaalsContact C-N 3.35Å; H741-M744 PolarHBondContact O-N 2.94Å; H741-Y745 WeakPolarHBondContact O-CB 3.26Å; H741-Y745 PolarHBondContact O-N 2.76Å; H741-I770 HydrophobicContact CB-CB 4.17Å; H741-I770 HydrophobicContact CB-CG2 4.07Å; H741-N771 HydrophobicContact CB-CB 3.77Å; H741-N771 PolarHBondContact CE1-ND2 3.29Å; H741-N771 PolarHBondContact NE2-ND2 3.37Å; H741-N771 VanDerWaalsContact NE2-ND2 3.14Å; H741-H774 AromaticContact CD2-CD2 3.8Å; H741-H774 AromaticContact CD2-CG 3.77Å; H741-H774 AromaticContact NE2-CD2 3.93Å
742N91Very high89.6Confident56 Ų5635.4 Ų35.430%0.29919%0.191SC..Hα-helixtrans-65.4-39.8176.5-69.6-37.8000111.1L711 S740 Y745 M746L711-N742 HydrophobicContact CD1-CB 3.73Å; S740-N742 PolarHBondContact O-N 3.16Å; S740-N742 PolarHBondContact OG-N 3.38Å; N742-Y745 WeakPolarHBondContact O-CB 3.31Å; N742-Y745 PolarHBondContact O-N 3.47Å; N742-M746 VanDerWaalsContact O-CG 3.3Å; N742-M746 WeakPolarHBondContact O-CG 3.37Å; N742-M746 PolarHBondContact O-N 3.38Å
743M92.8Very high90Very high4 Ų434.4 Ų34.42%0.0219%0.188CC..Hα-helixtrans-64.2-42.1174.4-179.7-115.353.500111.4L711 A734 S740 H741 Y745 M746 R747L711-M743 HydrophobicContact CD2-CB 4.1Å; L711-M743 HydrophobicContact CD2-CG 4.48Å; A734-M743 HydrophobicContact CB-CG 4.11Å; A734-M743 HydrophobicContact CB-SD 3.4Å; A734-M743 WeakPolarHBondContact CB-SD 3.28Å; S740-M743 WeakPolarHBondContact O-CB 3.31Å; S740-M743 PolarHBondContact O-N 3.15Å; S740-M743 VanDerWaalsContact O-N 3.11Å; H741-M743 VanDerWaalsContact C-N 3.35Å; M743-Y745 VanDerWaalsContact C-N 3.33Å; M743-Y745 PolarHBondContact O-N 2.99Å; M743-M746 PolarHBondContact O-N 3.19Å; M743-R747 HydrophobicContact CE-CG 4.43Å; M743-R747 PolarHBondContact O-N 3.36Å
744M93.5Very high90.3Very high20 Ų2040.1 Ų40.110%0.09921%0.21CC..Hα-helixtrans-65-41.7-179.8-68175.317300110.6S740 H741 M746 R747 G748 E766 A767 I770S740-M744 PolarHBondContact O-N 3.28Å; S740-M744 VanDerWaalsContact O-N 3.09Å; H741-M744 PolarHBondContact O-N 2.94Å; M744-M746 PolarHBondContact O-N 3.06Å; M744-R747 PolarHBondContact O-N 3.34Å; M744-G748 PolarHBondContact O-N 2.82Å; M744-E766 HydrophobicContact SD-CB 3.95Å; M744-A767 HydrophobicContact CB-CB 3.65Å; M744-I770 HydrophobicContact CE-CG1 4.07Å; M744-I770 HydrophobicContact SD-CG1 3.82Å
745Y95.3Very high90.5Very high18 Ų1842.3 Ų42.37%0.07123%0.233CC..Hα-helixtrans-56.4-47.1171.7169.6-100.1000112.4H741 N742 M743 R747 G748 Q749 Y764 H774 K776 T777 R780H741-Y745 WeakPolarHBondContact O-CB 3.26Å; H741-Y745 PolarHBondContact O-N 2.76Å; N742-Y745 WeakPolarHBondContact O-CB 3.31Å; N742-Y745 PolarHBondContact O-N 3.47Å; M743-Y745 VanDerWaalsContact C-N 3.33Å; M743-Y745 PolarHBondContact O-N 2.99Å; Y745-R747 VanDerWaalsContact C-N 3.35Å; Y745-R747 PolarHBondContact O-N 2.88Å; Y745-G748 PolarHBondContact O-N 3.17Å; Y745-Q749 HydrophobicContact CE1-CG 4.17Å; Y745-Q749 HydrophobicContact CE2-CG 4.31Å; Y745-Q749 PolarHBondContact O-N 3.33Å; Y745-Q749 PolarHBondContact OH-NE2 2.97Å; Y745-Y764 HydrophobicContact CD2-CD1 4.28Å; Y745-Y764 AromaticContact CD2-CE1 3.79Å; Y745-Y764 HydrophobicContact CD2-CE1 3.79Å; Y745-Y764 HydrophobicContact CE2-CE1 4.26Å; Y745-Y764 WeakPolarHBondContact O-CE1 3.5Å; Y745-H774 AromaticContact CD2-CE1 3.96Å; Y745-H774 AromaticContact CG-CE1 3.83Å; Y745-K776 HydrophobicContact CD2-CB 4.41Å; Y745-K776 HydrophobicContact CE1-CD 4.43Å; Y745-K776 HydrophobicContact CE2-CB 3.68Å; Y745-T777 WeakPolarHBondContact CD2-OG1 3.35Å; Y745-R780 HydrophobicContact CE2-CG 3.94Å
746M94.2Very high90.9Very high6 Ų642.1 Ų42.13%0.0323%0.232CC..Hα-helixtrans-63.5-38.5177.7-64.5-50.1-72.500112.3L711 A714 E715 I718 T730 N742 M743 M744 G748 Q749 I750L711-M746 HydrophobicContact CB-CG 4.49Å; L711-M746 HydrophobicContact CD2-CB 4.16Å; L711-M746 HydrophobicContact CD2-CG 3.64Å; A714-M746 HydrophobicContact CB-CE 3.98Å; E715-M746 HydrophobicContact CB-CE 3.53Å; E715-M746 HydrophobicContact CG-CE 4.02Å; E715-M746 VanDerWaalsContact N-CE 3.32Å; I718-M746 HydrophobicContact CD1-CE 3.51Å; T730-M746 HydrophobicContact CG2-CB 3.48Å; T730-M746 VanDerWaalsContact CG2-CB 3.48Å; T730-M746 HydrophobicContact CG2-CG 4.38Å; N742-M746 VanDerWaalsContact O-CG 3.3Å; N742-M746 WeakPolarHBondContact O-CG 3.37Å; N742-M746 PolarHBondContact O-N 3.38Å; M743-M746 PolarHBondContact O-N 3.19Å; M744-M746 PolarHBondContact O-N 3.06Å; M746-G748 VanDerWaalsContact C-N 3.34Å; M746-G748 PolarHBondContact O-N 3.21Å; M746-Q749 PolarHBondContact O-N 3.3Å; M746-I750 VanDerWaalsContact O-CG1 3.31Å; M746-I750 WeakPolarHBondContact O-CG1 3.25Å; M746-I750 PolarHBondContact O-N 3.16Å
747R93.8Very high91.5Very high63 Ų6343 Ų4324%0.23824%0.239CC..Hα-helixtrans-62.3-40.6173.1-74.8-170.9172.4-175-3.2112.5M743 M744 Y745 Q749 I750 A751 W763M743-R747 HydrophobicContact CE-CG 4.43Å; M743-R747 PolarHBondContact O-N 3.36Å; M744-R747 PolarHBondContact O-N 3.34Å; Y745-R747 VanDerWaalsContact C-N 3.35Å; Y745-R747 PolarHBondContact O-N 2.88Å; R747-Q749 VanDerWaalsContact C-N 3.34Å; R747-Q749 PolarHBondContact O-N 3.18Å; R747-I750 PolarHBondContact O-N 3.29Å; R747-A751 PolarHBondContact O-N 3.33Å; R747-W763 HydrophobicContact CB-CD2 3.96Å; R747-W763 HydrophobicContact CB-CE3 4.43Å; R747-W763 HydrophobicContact CB-CG 4.04Å
748G95.1Very high92.1Very high0 Ų046.3 Ų46.30%025%0.254CS..Hα-helixtrans-58.6-44.9172.900000112.1M744 Y745 M746 I750 A751 E752 A760 Y764M744-G748 PolarHBondContact O-N 2.82Å; Y745-G748 PolarHBondContact O-N 3.17Å; M746-G748 VanDerWaalsContact C-N 3.34Å; M746-G748 PolarHBondContact O-N 3.21Å; G748-I750 PolarHBondContact O-N 3.07Å; G748-A751 PolarHBondContact O-N 2.98Å; G748-E752 PolarHBondContact O-N 2.94Å; G748-A760 WeakPolarHBondContact O-CB 3.48Å; G748-Y764 VanDerWaalsContact C-OH 3.26Å
749Q95.1Very high92.7Very high28 Ų2845.2 Ų45.213%0.13124%0.241CC..Hα-helixtrans-63.5-38.5176.4-71-164.6-37.100112.9I718 Y745 M746 R747 A751 E752 L753 Y764I718-Q749 HydrophobicContact CD1-CB 3.75Å; Y745-Q749 HydrophobicContact CE1-CG 4.17Å; Y745-Q749 HydrophobicContact CE2-CG 4.31Å; Y745-Q749 PolarHBondContact O-N 3.33Å; Y745-Q749 PolarHBondContact OH-NE2 2.97Å; M746-Q749 PolarHBondContact O-N 3.3Å; R747-Q749 VanDerWaalsContact C-N 3.34Å; R747-Q749 PolarHBondContact O-N 3.18Å; Q749-A751 VanDerWaalsContact C-N 3.35Å; Q749-E752 PolarHBondContact O-N 3.49Å; Q749-L753 PolarHBondContact O-N 3.12Å; Q749-Y764 WeakPolarHBondContact CA-OH 3.35Å; Q749-Y764 WeakPolarHBondContact CG-OH 3.45Å; Q749-Y764 PolarHBondContact N-OH 3.45Å; Q749-Y764 VanDerWaalsContact N-OH 3.11Å
750I94.4Very high93.2Very high6 Ų640.2 Ų40.23%0.03121%0.21CC..Hα-helixtrans-65.1-40.1175.4-66.7163.6000110.8I718 P723 A726 T727 T730 M746 R747 G748 L753 R754I718-I750 HydrophobicContact CD1-CG1 3.77Å; I718-I750 HydrophobicContact CG1-CG1 4.02Å; P723-I750 HydrophobicContact CB-CG2 4.4Å; A726-I750 HydrophobicContact CB-CD1 3.84Å; A726-I750 HydrophobicContact CB-CG1 3.86Å; A726-I750 WeakPolarHBondContact O-CD1 3.05Å; T727-I750 WeakPolarHBondContact OG1-CG2 3.42Å; T730-I750 HydrophobicContact CG2-CD1 3.64Å; T730-I750 WeakPolarHBondContact OG1-CD1 3.28Å; M746-I750 VanDerWaalsContact O-CG1 3.31Å; M746-I750 WeakPolarHBondContact O-CG1 3.25Å; M746-I750 PolarHBondContact O-N 3.16Å; R747-I750 PolarHBondContact O-N 3.29Å; G748-I750 PolarHBondContact O-N 3.07Å; I750-L753 PolarHBondContact O-N 3.03Å; I750-R754 WeakPolarHBondContact O-CG 3.34Å; I750-R754 PolarHBondContact O-N 3.13Å
751A94.6Very high93.6Very high2 Ų240.6 Ų40.62%0.01721%0.209CC..Hα-helixtrans-64.9-39.8175.900000111.8R747 G748 Q749 R754 G755 N756 E759 A760R747-A751 PolarHBondContact O-N 3.33Å; G748-A751 PolarHBondContact O-N 2.98Å; Q749-A751 VanDerWaalsContact C-N 3.35Å; A751-R754 PolarHBondContact O-N 3.32Å; A751-G755 PolarHBondContact O-N 3.43Å; A751-N756 PolarHBondContact O-N 3.42Å; A751-E759 HydrophobicContact CB-CB 4.14Å; A751-E759 HydrophobicContact CB-CG 4.08Å; A751-A760 HydrophobicContact CB-CB 3.91Å
752E93.4Very high93.8Very high38 Ų3846.2 Ų46.218%0.17823%0.228CC..Hα-helixtrans-60.6-44.6171.2-72.5-158.9-124.400112.1G748 Q749 R754 G755 A760 Y764 R780 I784G748-E752 PolarHBondContact O-N 2.94Å; Q749-E752 PolarHBondContact O-N 3.49Å; E752-R754 PolarHBondContact O-N 3.45Å; E752-G755 WeakPolarHBondContact O-CA 3.31Å; E752-G755 PolarHBondContact O-N 3.03Å; E752-A760 HydrophobicContact CB-CB 4.48Å; E752-A760 HydrophobicContact CG-CB 3.49Å; E752-A760 VanDerWaalsContact CG-CB 3.49Å; E752-Y764 HydrophobicContact CG-CE2 4.33Å; E752-Y764 WeakPolarHBondContact OE1-CE2 3.27Å; E752-Y764 PolarHBondContact OE1-OH 3Å; E752-R780 IonicContact OE1-CZ 3.65Å; E752-R780 IonicContact OE1-NE 2.96Å; E752-R780 PolarHBondContact OE1-NE 3.26Å; E752-R780 IonicContact OE1-NH2 3.32Å; E752-R780 PolarHBondContact OE1-NH2 2.95Å; E752-R780 VanDerWaalsContact OE1-NH2 3.16Å; E752-R780 IonicContact OE2-CZ 2.72Å; E752-R780 IonicContact OE2-NE 3.93Å; E752-R780 IonicContact OE2-NH2 3.01Å; E752-R780 PolarHBondContact OE2-NH2 3.27Å; E752-I784 HydrophobicContact CG-CD1 4.18Å
753L93.1Very high94Very high61 Ų6145.9 Ų45.932%0.31922%0.223SC..Hα-helixtrans-62.3-29177.8-175.663000112.5P723 Q749 I750 G755P723-L753 HydrophobicContact CB-CD2 3.9Å; P723-L753 HydrophobicContact CB-CG 4.35Å; P723-L753 HydrophobicContact CG-CD2 4.42Å; Q749-L753 PolarHBondContact O-N 3.12Å; I750-L753 PolarHBondContact O-N 3.03Å; L753-G755 VanDerWaalsContact C-N 3.31Å
754R92.9Very high94.1Very high122 Ų12245.7 Ų45.746%0.4622%0.222SC..THydrogen-bonded Turntrans-80.2-8.3172.9-69.7175.6-179.8171.20.9113.8P723 T727 I750 A751 E752P723-R754 HydrophobicContact CB-CG 4.17Å; T727-R754 PolarHBondContact OG1-NH2 2.95Å; I750-R754 WeakPolarHBondContact O-CG 3.34Å; I750-R754 PolarHBondContact O-N 3.13Å; A751-R754 PolarHBondContact O-N 3.32Å; E752-R754 PolarHBondContact O-N 3.45Å
755G91.3Very high94.2Very high53 Ų5349.1 Ų49.155%0.54624%0.238SC..THydrogen-bonded Turntrans82.87.6-175.300000114.9A751 E752 L753 T757A751-G755 PolarHBondContact O-N 3.43Å; E752-G755 WeakPolarHBondContact O-CA 3.31Å; E752-G755 PolarHBondContact O-N 3.03Å; L753-G755 VanDerWaalsContact C-N 3.31Å; G755-T757 PolarHBondContact O-N 3Å
756N93.6Very high94.1Very high80 Ų8052.2 Ų52.243%0.42825%0.253SS..  trans-89.881.8-179.9-72.8-11.1000111.2A751 D758 E759 A760A751-N756 PolarHBondContact O-N 3.42Å; N756-D758 PolarHBondContact O-N 3.3Å; N756-E759 HydrophobicContact CB-CB 3.98Å; N756-E759 PolarHBondContact ND2-OE2 3.42Å; N756-E759 PolarHBondContact O-N 3.38Å; N756-A760 PolarHBondContact O-N 3.15Å
757T92.9Very high94.2Very high53 Ų5352 Ų5233%0.32525%0.251SS..Hα-helixtrans-64-37.5-176.852.10000113.9G755 A760 K761G755-T757 PolarHBondContact O-N 3Å; T757-A760 PolarHBondContact O-N 3.47Å; T757-K761 WeakPolarHBondContact O-CB 3.37Å; T757-K761 PolarHBondContact O-N 2.93Å
758D92.2Very high94.2Very high101 Ų10150.3 Ų50.354%0.5425%0.247SC..Hα-helixtrans-66.6-37.5178.3-74.9-36.3000112.7N756 R762N756-D758 PolarHBondContact O-N 3.3Å; D758-R762 WeakPolarHBondContact O-CG 3.22Å; D758-R762 PolarHBondContact O-N 3.18Å
759E94.3Very high94.2Very high64 Ų6454.5 Ų54.530%0.29928%0.276SS..Hα-helixtrans-70.7-44.7176.7-172.9-177.3179.300110.4A751 N756 K761 R762 W763A751-E759 HydrophobicContact CB-CB 4.14Å; A751-E759 HydrophobicContact CB-CG 4.08Å; N756-E759 HydrophobicContact CB-CB 3.98Å; N756-E759 PolarHBondContact ND2-OE2 3.42Å; N756-E759 PolarHBondContact O-N 3.38Å; E759-K761 VanDerWaalsContact C-N 3.3Å; E759-K761 PolarHBondContact O-N 2.59Å; E759-R762 PolarHBondContact O-N 2.88Å; E759-W763 VanDerWaalsContact O-CD1 3.24Å; E759-W763 PolarHBondContact O-N 3.06Å; E759-W763 VanDerWaalsContact O-N 3.1Å
760A94.9Very high94.1Very high0 Ų057.1 Ų57.10%029%0.29CS..Hα-helixtrans-56.8-44.8175.400000112G748 A751 E752 N756 T757 R762 W763 Y764 I784G748-A760 WeakPolarHBondContact O-CB 3.48Å; A751-A760 HydrophobicContact CB-CB 3.91Å; E752-A760 HydrophobicContact CB-CB 4.48Å; E752-A760 HydrophobicContact CG-CB 3.49Å; E752-A760 VanDerWaalsContact CG-CB 3.49Å; N756-A760 PolarHBondContact O-N 3.15Å; T757-A760 PolarHBondContact O-N 3.47Å; A760-R762 PolarHBondContact O-N 3.22Å; A760-W763 PolarHBondContact O-N 2.93Å; A760-Y764 HydrophobicContact CB-CE2 4.25Å; A760-Y764 WeakPolarHBondContact O-CD2 3.42Å; A760-Y764 PolarHBondContact O-N 3.39Å; A760-I784 HydrophobicContact CB-CD1 3.66Å
761K95.1Very high94Very high37 Ų3758.7 Ų58.716%0.16130%0.299CS..Hα-helixtrans-55.8-48.3176-174.4-174.5163.9-165.80112.1T757 E759 Y764 E765 L781 I784 L788T757-K761 WeakPolarHBondContact O-CB 3.37Å; T757-K761 PolarHBondContact O-N 2.93Å; E759-K761 VanDerWaalsContact C-N 3.3Å; E759-K761 PolarHBondContact O-N 2.59Å; K761-Y764 PolarHBondContact O-N 3Å; K761-E765 WeakPolarHBondContact CE-OE1 3.47Å; K761-E765 IonicContact NZ-OE1 3.92Å; K761-E765 WeakPolarHBondContact O-CG 3.45Å; K761-E765 PolarHBondContact O-N 3.27Å; K761-L781 HydrophobicContact CG-CD1 3.85Å; K761-I784 HydrophobicContact CB-CG2 4.19Å; K761-L788 HydrophobicContact CD-CD1 4.39Å
762R95.9Very high93.9Very high158 Ų15862.8 Ų62.860%0.59633%0.325SS*.Hα-helixtrans-60.9-46.1179.6-68.9178-150.7162.56.1111.4D758 E759 A760 Y764 E765 E766D758-R762 WeakPolarHBondContact O-CG 3.22Å; D758-R762 PolarHBondContact O-N 3.18Å; E759-R762 PolarHBondContact O-N 2.88Å; A760-R762 PolarHBondContact O-N 3.22Å; R762-Y764 VanDerWaalsContact C-N 3.28Å; R762-Y764 PolarHBondContact O-N 3.3Å; R762-E765 PolarHBondContact O-N 3.47Å; R762-E766 WeakPolarHBondContact O-CG 3.4Å; R762-E766 PolarHBondContact O-N 3.4Å
763W95.1Very high93.9Very high50 Ų5064.9 Ų64.919%0.18934%0.341CS..Hα-helixtrans-61.6-36.2177.8-74.7121.1000112.8R747 E759 A760 E766 A767R747-W763 HydrophobicContact CB-CD2 3.96Å; R747-W763 HydrophobicContact CB-CE3 4.43Å; R747-W763 HydrophobicContact CB-CG 4.04Å; E759-W763 VanDerWaalsContact O-CD1 3.24Å; E759-W763 PolarHBondContact O-N 3.06Å; E759-W763 VanDerWaalsContact O-N 3.1Å; A760-W763 PolarHBondContact O-N 2.93Å; W763-E766 VanDerWaalsContact CE3-OE2 3.29Å; W763-E766 WeakPolarHBondContact CZ3-OE2 3.38Å; W763-A767 WeakPolarHBondContact O-CB 3.5Å; W763-A767 PolarHBondContact O-N 3.42Å
764Y96.2Very high93.9Very high0 Ų063.2 Ų63.20%033%0.331CS..Hα-helixtrans-71.5-38.7174.5-66.1-34.6000113.3Y745 G748 Q749 E752 A760 K761 R762 E766 A767 L768 T777 R780 I784Y745-Y764 HydrophobicContact CD2-CD1 4.28Å; Y745-Y764 AromaticContact CD2-CE1 3.79Å; Y745-Y764 HydrophobicContact CD2-CE1 3.79Å; Y745-Y764 HydrophobicContact CE2-CE1 4.26Å; Y745-Y764 WeakPolarHBondContact O-CE1 3.5Å; G748-Y764 VanDerWaalsContact C-OH 3.26Å; Q749-Y764 WeakPolarHBondContact CA-OH 3.35Å; Q749-Y764 WeakPolarHBondContact CG-OH 3.45Å; Q749-Y764 PolarHBondContact N-OH 3.45Å; Q749-Y764 VanDerWaalsContact N-OH 3.11Å; E752-Y764 HydrophobicContact CG-CE2 4.33Å; E752-Y764 WeakPolarHBondContact OE1-CE2 3.27Å; E752-Y764 PolarHBondContact OE1-OH 3Å; A760-Y764 HydrophobicContact CB-CE2 4.25Å; A760-Y764 WeakPolarHBondContact O-CD2 3.42Å; A760-Y764 PolarHBondContact O-N 3.39Å; K761-Y764 PolarHBondContact O-N 3Å; R762-Y764 VanDerWaalsContact C-N 3.28Å; R762-Y764 PolarHBondContact O-N 3.3Å; Y764-E766 VanDerWaalsContact C-N 3.34Å; Y764-A767 PolarHBondContact O-N 3.42Å; Y764-L768 WeakPolarHBondContact O-CB 3.45Å; Y764-L768 WeakPolarHBondContact O-CG 3.31Å; Y764-L768 PolarHBondContact O-N 3.28Å; Y764-T777 HydrophobicContact CD1-CG2 3.75Å; Y764-T777 HydrophobicContact CG-CG2 3.94Å; Y764-T777 VanDerWaalsContact O-CG2 3.25Å; Y764-T777 WeakPolarHBondContact O-CG2 3.33Å; Y764-R780 HydrophobicContact CD2-CB 3.99Å; Y764-R780 HydrophobicContact CE1-CB 4.12Å; Y764-R780 HydrophobicContact CE1-CG 4.49Å; Y764-R780 HydrophobicContact CE2-CB 3.42Å; Y764-R780 VanDerWaalsContact CE2-CB 3.42Å; Y764-R780 HydrophobicContact CE2-CG 4.36Å; Y764-R780 VanDerWaalsContact CZ-CB 3.49Å; Y764-I784 HydrophobicContact CD2-CD1 3.74Å; Y764-I784 HydrophobicContact CE2-CD1 3.64Å
765E94.8Very high94Very high92 Ų9258.4 Ų58.443%0.4332%0.315SS..Hα-helixtrans-62.1-42.1172.2-72.7174.9161.100111.1K761 R762 L768 S769 L781K761-E765 WeakPolarHBondContact CE-OE1 3.47Å; K761-E765 IonicContact NZ-OE1 3.92Å; K761-E765 WeakPolarHBondContact O-CG 3.45Å; K761-E765 PolarHBondContact O-N 3.27Å; R762-E765 PolarHBondContact O-N 3.47Å; E765-L768 PolarHBondContact O-N 3.03Å; E765-S769 PolarHBondContact O-N 2.98Å; E765-L781 HydrophobicContact CG-CD1 4.38Å; E765-L781 HydrophobicContact CG-CD2 4.39Å
766E94.1Very high94.2Very high83 Ų8360.3 Ų60.339%0.38831%0.309SS..Hα-helixtrans-63.3-46.3173.6-73.7-177.6-166.400111.8M744 R762 W763 Y764 L768 S769 I770M744-E766 HydrophobicContact SD-CB 3.95Å; R762-E766 WeakPolarHBondContact O-CG 3.4Å; R762-E766 PolarHBondContact O-N 3.4Å; W763-E766 VanDerWaalsContact CE3-OE2 3.29Å; W763-E766 WeakPolarHBondContact CZ3-OE2 3.38Å; Y764-E766 VanDerWaalsContact C-N 3.34Å; E766-L768 VanDerWaalsContact C-N 3.28Å; E766-L768 PolarHBondContact O-N 2.83Å; E766-S769 WeakPolarHBondContact O-CB 3.28Å; E766-S769 PolarHBondContact O-N 2.82Å; E766-S769 VanDerWaalsContact O-N 3.07Å; E766-S769 PolarHBondContact O-OG 3.44Å; E766-I770 PolarHBondContact O-N 3.19Å
767A94.8Very high94.3Very high0 Ų056.5 Ų56.50%029%0.288CS..Hα-helixtrans-58.3-40.2176.600000112.2M744 W763 Y764 I770 N771 T777M744-A767 HydrophobicContact CB-CB 3.65Å; W763-A767 WeakPolarHBondContact O-CB 3.5Å; W763-A767 PolarHBondContact O-N 3.42Å; Y764-A767 PolarHBondContact O-N 3.42Å; A767-I770 PolarHBondContact O-N 3.44Å; A767-N771 PolarHBondContact O-N 3.28Å; A767-T777 HydrophobicContact CB-CG2 3.97Å
768L94.9Very high94.5Very high29 Ų2954.6 Ų54.615%0.15228%0.276CS..Hα-helixtrans-73.7-27.3176.1-74.4174.7000113.4Y764 E765 E766 I770 N771 P772 T777 M778 L781Y764-L768 WeakPolarHBondContact O-CB 3.45Å; Y764-L768 WeakPolarHBondContact O-CG 3.31Å; Y764-L768 PolarHBondContact O-N 3.28Å; E765-L768 PolarHBondContact O-N 3.03Å; E766-L768 VanDerWaalsContact C-N 3.28Å; E766-L768 PolarHBondContact O-N 2.83Å; L768-I770 PolarHBondContact O-N 2.92Å; L768-N771 WeakPolarHBondContact CD2-O 3.45Å; L768-N771 CarbonylContact O-C 3.51Å; L768-P772 VanDerWaalsContact O-CA 3.26Å; L768-P772 WeakPolarHBondContact O-CA 3.37Å; L768-P772 WeakPolarHBondContact O-CG 3.3Å; L768-P772 VanDerWaalsContact O-N 3.13Å; L768-T777 HydrophobicContact CD1-CG2 4.03Å; L768-T777 HydrophobicContact CD2-CG2 4.12Å; L768-T777 HydrophobicContact CG-CG2 3.61Å; L768-M778 HydrophobicContact CD1-CG 4.23Å; L768-M778 HydrophobicContact CD2-CG 3.66Å; L768-L781 HydrophobicContact CD1-CD2 3.6Å
769S94.9Very high94.7Very high88 Ų8850.8 Ų50.862%0.61526%0.255SS*.Hα-helixtrans-65.2-30.2172.179.60000112E765 E766E765-S769 PolarHBondContact O-N 2.98Å; E766-S769 WeakPolarHBondContact O-CB 3.28Å; E766-S769 PolarHBondContact O-N 2.82Å; E766-S769 VanDerWaalsContact O-N 3.07Å; E766-S769 PolarHBondContact O-OG 3.44Å
770I92.6Very high94.8Very high83 Ų8351 Ų5143%0.42625%0.253SS..Hα-helixtrans-84.3-47.9175.3-57.9-57.1000111.6H741 M744 E766 A767 L768H741-I770 HydrophobicContact CB-CB 4.17Å; H741-I770 HydrophobicContact CB-CG2 4.07Å; M744-I770 HydrophobicContact CE-CG1 4.07Å; M744-I770 HydrophobicContact SD-CG1 3.82Å; E766-I770 PolarHBondContact O-N 3.19Å; A767-I770 PolarHBondContact O-N 3.44Å; L768-I770 PolarHBondContact O-N 2.92Å
771N92.2Very high94.8Very high38 Ų3851.5 Ų51.520%0.20326%0.256CS..  trans-128.393.1177.9-174.8-2.7000110.7H741 A767 L768 T773 H774H741-N771 HydrophobicContact CB-CB 3.77Å; H741-N771 PolarHBondContact CE1-ND2 3.29Å; H741-N771 PolarHBondContact NE2-ND2 3.37Å; H741-N771 VanDerWaalsContact NE2-ND2 3.14Å; A767-N771 PolarHBondContact O-N 3.28Å; L768-N771 WeakPolarHBondContact CD2-O 3.45Å; L768-N771 CarbonylContact O-C 3.51Å; N771-T773 PolarHBondContact O-N 2.94Å; N771-T773 VanDerWaalsContact O-N 3.08Å; N771-T773 PolarHBondContact OD1-N 2.71Å; N771-T773 PolarHBondContact OD1-OG1 3.1Å; N771-H774 HydrophobicContact CB-CB 4.24Å; N771-H774 PolarHBondContact O-N 2.77Å
772P93.4Very high94.8Very high88 Ų8849.8 Ų49.857%0.57125%0.248SC*.THydrogen-bonded Turntrans-62.6-16.9-177.5-24.934.8000114.7L768L768-P772 VanDerWaalsContact O-CA 3.26Å; L768-P772 WeakPolarHBondContact O-CA 3.37Å; L768-P772 WeakPolarHBondContact O-CG 3.3Å; L768-P772 VanDerWaalsContact O-N 3.13Å
773T92.4Very high94.8Very high82 Ų8243.6 Ų43.650%0.50323%0.227SC..THydrogen-bonded Turntrans-105.815.2-176.759.40000112.6N771 V775 V804N771-T773 PolarHBondContact O-N 2.94Å; N771-T773 VanDerWaalsContact O-N 3.08Å; N771-T773 PolarHBondContact OD1-N 2.71Å; N771-T773 PolarHBondContact OD1-OG1 3.1Å; T773-V775 PolarHBondContact O-N 3.42Å; T773-V804 HydrophobicContact CG2-CG2 4.19Å; T773-V804 WeakPolarHBondContact O-CG1 3.25Å
774H94.4Very high94.8Very high26 Ų2641.2 Ų41.212%0.1222%0.218CC..  trans-77.595.1178.5-171.6-118.5000111.9H741 Y745 N771 K776 T777 M778H741-H774 AromaticContact CD2-CD2 3.8Å; H741-H774 AromaticContact CD2-CG 3.77Å; H741-H774 AromaticContact NE2-CD2 3.93Å; Y745-H774 AromaticContact CD2-CE1 3.96Å; Y745-H774 AromaticContact CG-CE1 3.83Å; N771-H774 HydrophobicContact CB-CB 4.24Å; N771-H774 PolarHBondContact O-N 2.77Å; H774-K776 PolarHBondContact O-N 3.02Å; H774-T777 PolarHBondContact ND1-N 3.33Å; H774-T777 PolarHBondContact ND1-OG1 2.94Å; H774-T777 PolarHBondContact O-N 2.94Å; H774-M778 WeakPolarHBondContact O-CG 3.49Å; H774-M778 PolarHBondContact O-N 3.32Å; H774-M778 VanDerWaalsContact O-N 3.1Å
775V94.5Very high94.7Very high21 Ų2141.7 Ų41.713%0.12722%0.22CC..Hα-helixtrans-53.5-44.6-172.7-1790000113.4T773 T777 M778 Q779 V804 N805 V811T773-V775 PolarHBondContact O-N 3.42Å; V775-T777 VanDerWaalsContact C-N 3.32Å; V775-T777 PolarHBondContact O-N 2.96Å; V775-M778 PolarHBondContact O-N 2.99Å; V775-Q779 PolarHBondContact O-N 3.09Å; V775-V804 HydrophobicContact CG2-CB 4.01Å; V775-V804 HydrophobicContact CG2-CG1 3.53Å; V775-N805 HydrophobicContact CG1-CB 4.34Å; V775-N805 HydrophobicContact CG2-CB 3.73Å; V775-V811 HydrophobicContact CG1-CG2 3.7Å
776K94.4Very high94.6Very high94 Ų9439.3 Ų39.341%0.40921%0.209SC..Hα-helixtrans-62.2-39.4179.7-68-175175.4-175.20111.9Y745 H774 Q779 R780Y745-K776 HydrophobicContact CD2-CB 4.41Å; Y745-K776 HydrophobicContact CE1-CD 4.43Å; Y745-K776 HydrophobicContact CE2-CB 3.68Å; H774-K776 PolarHBondContact O-N 3.02Å; K776-Q779 PolarHBondContact O-N 3.16Å; K776-R780 WeakPolarHBondContact O-CG 3.41Å; K776-R780 PolarHBondContact O-N 3.21Å; K776-R780 VanDerWaalsContact O-N 3.11Å
777T96.3Very high94.6Very high0 Ų041 Ų410%022%0.217CC..Hα-helixtrans-66.7-42.9175.2-62.80000111.4Y745 Y764 A767 L768 H774 V775 Q779 R780 L781Y745-T777 WeakPolarHBondContact CD2-OG1 3.35Å; Y764-T777 HydrophobicContact CD1-CG2 3.75Å; Y764-T777 HydrophobicContact CG-CG2 3.94Å; Y764-T777 VanDerWaalsContact O-CG2 3.25Å; Y764-T777 WeakPolarHBondContact O-CG2 3.33Å; A767-T777 HydrophobicContact CB-CG2 3.97Å; L768-T777 HydrophobicContact CD1-CG2 4.03Å; L768-T777 HydrophobicContact CD2-CG2 4.12Å; L768-T777 HydrophobicContact CG-CG2 3.61Å; H774-T777 PolarHBondContact ND1-N 3.33Å; H774-T777 PolarHBondContact ND1-OG1 2.94Å; H774-T777 PolarHBondContact O-N 2.94Å; V775-T777 VanDerWaalsContact C-N 3.32Å; V775-T777 PolarHBondContact O-N 2.96Å; T777-Q779 VanDerWaalsContact C-N 3.29Å; T777-Q779 PolarHBondContact O-N 3.42Å; T777-R780 PolarHBondContact O-N 3.47Å; T777-L781 VanDerWaalsContact O-CB 3.32Å; T777-L781 WeakPolarHBondContact O-CB 3.39Å; T777-L781 PolarHBondContact O-N 3.32Å
778M96.8Very high94.5Very high13 Ų1344.2 Ų44.26%0.06423%0.233CC..Hα-helixtrans-59.6-42.2177.5-61173.581.400111.4L768 H774 V775 G782 V797 D800 A801L768-M778 HydrophobicContact CD1-CG 4.23Å; L768-M778 HydrophobicContact CD2-CG 3.66Å; H774-M778 WeakPolarHBondContact O-CG 3.49Å; H774-M778 PolarHBondContact O-N 3.32Å; H774-M778 VanDerWaalsContact O-N 3.1Å; V775-M778 PolarHBondContact O-N 2.99Å; M778-G782 PolarHBondContact O-N 3.11Å; M778-V797 HydrophobicContact CB-CG1 3.9Å; M778-V797 WeakPolarHBondContact CE-O 3.17Å; M778-V797 VanDerWaalsContact O-CG1 3.31Å; M778-V797 WeakPolarHBondContact O-CG1 3.44Å; M778-D800 HydrophobicContact CE-CB 3.45Å; M778-D800 VanDerWaalsContact CE-CB 3.45Å; M778-A801 HydrophobicContact CB-CB 3.75Å; M778-A801 HydrophobicContact CE-CB 4.01Å; M778-A801 VanDerWaalsContact CE-N 3.3Å; M778-A801 HydrophobicContact CG-CB 4.47Å; M778-A801 HydrophobicContact SD-CB 3.96Å
779Q96.4Very high94.4Very high20 Ų2049.7 Ų49.79%0.09326%0.258CS..Hα-helixtrans-59.5-53.5175.3-174.1-153.1-11.800111.6V775 K776 T777 L781 G782 L783 V811V775-Q779 PolarHBondContact O-N 3.09Å; K776-Q779 PolarHBondContact O-N 3.16Å; T777-Q779 VanDerWaalsContact C-N 3.29Å; T777-Q779 PolarHBondContact O-N 3.42Å; Q779-L781 PolarHBondContact O-N 3Å; Q779-G782 WeakPolarHBondContact O-CA 3.41Å; Q779-G782 PolarHBondContact O-N 3.04Å; Q779-G782 VanDerWaalsContact O-N 3.15Å; Q779-L783 HydrophobicContact CG-CD1 4.48Å; Q779-L783 PolarHBondContact O-N 2.92Å; Q779-V811 HydrophobicContact CB-CG2 4.04Å; Q779-V811 HydrophobicContact CG-CG2 4.27Å
780R96Very high94.4Very high69 Ų6951.4 Ų51.426%0.2625%0.251SS..Hα-helixtrans-63.2-41.1-179.2-62.3-56-68.6-163.1-5.7112.2Y745 E752 Y764 K776 T777 G782 L783 I784Y745-R780 HydrophobicContact CE2-CG 3.94Å; E752-R780 IonicContact OE1-CZ 3.65Å; E752-R780 IonicContact OE1-NE 2.96Å; E752-R780 PolarHBondContact OE1-NE 3.26Å; E752-R780 IonicContact OE1-NH2 3.32Å; E752-R780 PolarHBondContact OE1-NH2 2.95Å; E752-R780 VanDerWaalsContact OE1-NH2 3.16Å; E752-R780 IonicContact OE2-CZ 2.72Å; E752-R780 IonicContact OE2-NE 3.93Å; E752-R780 IonicContact OE2-NH2 3.01Å; E752-R780 PolarHBondContact OE2-NH2 3.27Å; Y764-R780 HydrophobicContact CD2-CB 3.99Å; Y764-R780 HydrophobicContact CE1-CB 4.12Å; Y764-R780 HydrophobicContact CE1-CG 4.49Å; Y764-R780 HydrophobicContact CE2-CB 3.42Å; Y764-R780 VanDerWaalsContact CE2-CB 3.42Å; Y764-R780 HydrophobicContact CE2-CG 4.36Å; Y764-R780 VanDerWaalsContact CZ-CB 3.49Å; K776-R780 WeakPolarHBondContact O-CG 3.41Å; K776-R780 PolarHBondContact O-N 3.21Å; K776-R780 VanDerWaalsContact O-N 3.11Å; T777-R780 PolarHBondContact O-N 3.47Å; R780-G782 VanDerWaalsContact C-N 3.33Å; R780-G782 PolarHBondContact O-N 2.59Å; R780-L783 PolarHBondContact O-N 2.96Å; R780-I784 WeakPolarHBondContact O-CG1 3.26Å; R780-I784 PolarHBondContact O-N 3.45Å
781L95.9Very high94.5Very high11 Ų1150.9 Ų50.96%0.05825%0.245CC..Hα-helixtrans-62.2-41.7173.6-177.660.6000111.5K761 E765 L768 T777 Q779 L783 I784 L785K761-L781 HydrophobicContact CG-CD1 3.85Å; E765-L781 HydrophobicContact CG-CD1 4.38Å; E765-L781 HydrophobicContact CG-CD2 4.39Å; L768-L781 HydrophobicContact CD1-CD2 3.6Å; T777-L781 VanDerWaalsContact O-CB 3.32Å; T777-L781 WeakPolarHBondContact O-CB 3.39Å; T777-L781 PolarHBondContact O-N 3.32Å; Q779-L781 PolarHBondContact O-N 3Å; L781-L783 VanDerWaalsContact C-N 3.35Å; L781-L783 PolarHBondContact O-N 3.4Å; L781-I784 PolarHBondContact O-N 3.38Å; L781-L785 HydrophobicContact CD1-CD1 4.5Å; L781-L785 HydrophobicContact CD1-CG 4.42Å; L781-L785 HydrophobicContact CG-CD1 4.13Å; L781-L785 WeakPolarHBondContact O-CB 3.37Å; L781-L785 VanDerWaalsContact O-CG 3.25Å; L781-L785 WeakPolarHBondContact O-CG 3.42Å; L781-L785 PolarHBondContact O-N 3.23Å
782G95.1Very high94.6Very high0 Ų053.2 Ų53.20%026%0.264CS..Hα-helixtrans-57.8-45173.800000112.4M778 Q779 R780 L785 H786 S794M778-G782 PolarHBondContact O-N 3.11Å; Q779-G782 WeakPolarHBondContact O-CA 3.41Å; Q779-G782 PolarHBondContact O-N 3.04Å; Q779-G782 VanDerWaalsContact O-N 3.15Å; R780-G782 VanDerWaalsContact C-N 3.33Å; R780-G782 PolarHBondContact O-N 2.59Å; G782-L785 PolarHBondContact O-N 3.21Å; G782-H786 WeakPolarHBondContact O-CB 3.37Å; G782-H786 PolarHBondContact O-N 2.93Å; G782-S794 WeakPolarHBondContact O-CB 3.35Å; G782-S794 PolarHBondContact O-OG 3.03Å
783L95Very high94.6Very high29 Ų2953.1 Ų53.115%0.15226%0.258CS..Hα-helixtrans-64-43176-72.5171.2000112.5Q779 R780 L781 L785 H786 Q787Q779-L783 HydrophobicContact CG-CD1 4.48Å; Q779-L783 PolarHBondContact O-N 2.92Å; R780-L783 PolarHBondContact O-N 2.96Å; L781-L783 VanDerWaalsContact C-N 3.35Å; L781-L783 PolarHBondContact O-N 3.4Å; L783-L785 PolarHBondContact O-N 3.49Å; L783-H786 WeakPolarHBondContact O-CB 3.49Å; L783-H786 PolarHBondContact O-N 3.3Å; L783-Q787 WeakPolarHBondContact O-CG 3.48Å; L783-Q787 PolarHBondContact O-N 3.04Å
784I94.7Very high94.8Very high0 Ų049.2 Ų49.20%023%0.234CC..Hα-helixtrans-63.5-42.5174.7-68.2178.2000110.7E752 A760 K761 Y764 R780 L781 H786 Q787 L788E752-I784 HydrophobicContact CG-CD1 4.18Å; A760-I784 HydrophobicContact CB-CD1 3.66Å; K761-I784 HydrophobicContact CB-CG2 4.19Å; Y764-I784 HydrophobicContact CD2-CD1 3.74Å; Y764-I784 HydrophobicContact CE2-CD1 3.64Å; R780-I784 WeakPolarHBondContact O-CG1 3.26Å; R780-I784 PolarHBondContact O-N 3.45Å; L781-I784 PolarHBondContact O-N 3.38Å; I784-H786 VanDerWaalsContact C-N 3.28Å; I784-H786 PolarHBondContact O-N 2.73Å; I784-Q787 WeakPolarHBondContact O-CB 3.45Å; I784-Q787 PolarHBondContact O-N 2.64Å; I784-L788 HydrophobicContact CG2-CD1 4.08Å; I784-L788 HydrophobicContact CG2-CG 4.43Å; I784-L788 VanDerWaalsContact O-CG 3.32Å; I784-L788 WeakPolarHBondContact O-CG 3.4Å; I784-L788 PolarHBondContact O-N 3.27Å
785L94.6Very high94.8Very high10 Ų1049.8 Ų49.85%0.05224%0.237CC..Hα-helixtrans-63.7-35.1176.4-71.4170.6000112.2L781 G782 L783 L788 Q789 R790 L793 V797L781-L785 HydrophobicContact CD1-CD1 4.5Å; L781-L785 HydrophobicContact CD1-CG 4.42Å; L781-L785 HydrophobicContact CG-CD1 4.13Å; L781-L785 WeakPolarHBondContact O-CB 3.37Å; L781-L785 VanDerWaalsContact O-CG 3.25Å; L781-L785 WeakPolarHBondContact O-CG 3.42Å; L781-L785 PolarHBondContact O-N 3.23Å; G782-L785 PolarHBondContact O-N 3.21Å; L783-L785 PolarHBondContact O-N 3.49Å; L785-L788 CarbonylContact O-C 3.56Å; L785-L788 PolarHBondContact O-N 2.66Å; L785-Q789 PolarHBondContact O-N 2.99Å; L785-R790 HydrophobicContact CD2-CB 4.32Å; L785-R790 PolarHBondContact O-N 2.88Å; L785-L793 HydrophobicContact CD1-CB 4.17Å; L785-V797 HydrophobicContact CD1-CG2 4.19Å
786H94.3Very high94.9Very high42 Ų4255.1 Ų55.119%0.19426%0.258CS..Hα-helixtrans-63.5-46.5172.6173.8-112.7000111.4G782 L783 I784 L788 Q789 Y791 V818G782-H786 WeakPolarHBondContact O-CB 3.37Å; G782-H786 PolarHBondContact O-N 2.93Å; L783-H786 WeakPolarHBondContact O-CB 3.49Å; L783-H786 PolarHBondContact O-N 3.3Å; I784-H786 VanDerWaalsContact C-N 3.28Å; I784-H786 PolarHBondContact O-N 2.73Å; H786-L788 VanDerWaalsContact C-N 3.27Å; H786-L788 PolarHBondContact O-N 2.95Å; H786-Q789 WeakPolarHBondContact O-CA 3.31Å; H786-Q789 PolarHBondContact O-N 2.93Å; H786-Y791 AromaticContact CD2-CD1 3.68Å; H786-Y791 AromaticContact CD2-CE1 3.5Å; H786-Y791 AromaticContact NE2-CE1 3.89Å; H786-V818 HydrophobicContact CB-CG2 3.87Å
787Q92.1Very high95Very high118 Ų11852 Ų5255%0.55125%0.247SC*.Hα-helixtrans-60.3-36.2174.9-69.8174.2-1.600112.5L783 I784 Q789L783-Q787 WeakPolarHBondContact O-CG 3.48Å; L783-Q787 PolarHBondContact O-N 3.04Å; I784-Q787 WeakPolarHBondContact O-CB 3.45Å; I784-Q787 PolarHBondContact O-N 2.64Å; Q787-Q789 PolarHBondContact O-N 3.15Å
788L92.7Very high95Very high67 Ų6752 Ų5235%0.35125%0.247SC..THydrogen-bonded Turntrans-77.68.3174.2-64.2176.2000113.7K761 I784 L785 H786 R790K761-L788 HydrophobicContact CD-CD1 4.39Å; I784-L788 HydrophobicContact CG2-CD1 4.08Å; I784-L788 HydrophobicContact CG2-CG 4.43Å; I784-L788 VanDerWaalsContact O-CG 3.32Å; I784-L788 WeakPolarHBondContact O-CG 3.4Å; I784-L788 PolarHBondContact O-N 3.27Å; L785-L788 CarbonylContact O-C 3.56Å; L785-L788 PolarHBondContact O-N 2.66Å; H786-L788 VanDerWaalsContact C-N 3.27Å; H786-L788 PolarHBondContact O-N 2.95Å; L788-R790 HydrophobicContact CB-CG 4.34Å; L788-R790 PolarHBondContact O-N 2.75Å; L788-R790 VanDerWaalsContact O-N 3.15Å
789Q93.5Very high94.9Very high144 Ų14457.2 Ų57.267%0.67327%0.266SS*.THydrogen-bonded Turntrans58.422.4-178.6-55.8-179.2-7.500114.4L785 H786 Q787 Y791L785-Q789 PolarHBondContact O-N 2.99Å; H786-Q789 WeakPolarHBondContact O-CA 3.31Å; H786-Q789 PolarHBondContact O-N 2.93Å; Q787-Q789 PolarHBondContact O-N 3.15Å; Q789-Y791 VanDerWaalsContact C-N 3.29Å; Q789-Y791 HydrophobicContact CB-CE2 4.27Å; Q789-Y791 PolarHBondContact O-N 3.18Å
790R95Very high94.8Very high124 Ų12459.9 Ų59.947%0.46828%0.281SS..  trans-91.960.9176.5-61.8-175.1-176.3-165.10.7110.4L785 L788 S792 L793 S794L785-R790 HydrophobicContact CD2-CB 4.32Å; L785-R790 PolarHBondContact O-N 2.88Å; L788-R790 HydrophobicContact CB-CG 4.34Å; L788-R790 PolarHBondContact O-N 2.75Å; L788-R790 VanDerWaalsContact O-N 3.15Å; R790-S792 VanDerWaalsContact C-N 3.33Å; R790-S792 PolarHBondContact O-N 3.3Å; R790-L793 HydrophobicContact CB-CD1 4.47Å; R790-L793 PolarHBondContact O-N 3.19Å; R790-S794 PolarHBondContact O-N 2.66Å
791Y94.4Very high94.7Very high73 Ų7356.6 Ų56.629%0.28627%0.269SS..Hα-helixtrans-59.2-37.4-168.9-54.8-53.9000114.4H786 Q789 S794 E795 V818 A821 Q822H786-Y791 AromaticContact CD2-CD1 3.68Å; H786-Y791 AromaticContact CD2-CE1 3.5Å; H786-Y791 AromaticContact NE2-CE1 3.89Å; Q789-Y791 VanDerWaalsContact C-N 3.29Å; Q789-Y791 HydrophobicContact CB-CE2 4.27Å; Q789-Y791 PolarHBondContact O-N 3.18Å; Y791-S794 PolarHBondContact O-N 3.05Å; Y791-E795 WeakPolarHBondContact O-CB 3.32Å; Y791-E795 PolarHBondContact O-N 3.04Å; Y791-V818 WeakPolarHBondContact O-CG1 3.41Å; Y791-A821 HydrophobicContact CD1-CB 4.17Å; Y791-A821 HydrophobicContact CE1-CB 3.75Å; Y791-Q822 HydrophobicContact CG-CG 4.23Å; Y791-Q822 PolarHBondContact O-NE2 2.99Å
792S93.8Very high94.6Very high87 Ų8756.6 Ų56.661%0.60827%0.269SS*.Hα-helixtrans-68-40.3-179.753.70000113.1R790 K796R790-S792 VanDerWaalsContact C-N 3.33Å; R790-S792 PolarHBondContact O-N 3.3Å; S792-K796 PolarHBondContact O-N 3Å; S792-K796 VanDerWaalsContact O-N 3.12Å
793L94.6Very high94.4Very high86 Ų8660.4 Ų60.445%0.4529%0.287SS..Hα-helixtrans-70.2-40.5175.1-69174.9000111.1L785 R790 K796 V797L785-L793 HydrophobicContact CD1-CB 4.17Å; R790-L793 HydrophobicContact CB-CD1 4.47Å; R790-L793 PolarHBondContact O-N 3.19Å; L793-K796 PolarHBondContact O-N 3.34Å; L793-V797 WeakPolarHBondContact O-CG2 3.34Å; L793-V797 PolarHBondContact O-N 3.49Å
794S95.7Very high94.2Very high0 Ų061.7 Ų61.70%030%0.296CS..Hα-helixtrans-59.1-50.2175.5-177.70000111.3G782 R790 Y791 K796 V797 L798 V818G782-S794 WeakPolarHBondContact O-CB 3.35Å; G782-S794 PolarHBondContact O-OG 3.03Å; R790-S794 PolarHBondContact O-N 2.66Å; Y791-S794 PolarHBondContact O-N 3.05Å; S794-K796 VanDerWaalsContact C-N 3.32Å; S794-K796 PolarHBondContact O-N 3.29Å; S794-V797 PolarHBondContact O-N 2.83Å; S794-L798 WeakPolarHBondContact O-CB 3.45Å; S794-L798 VanDerWaalsContact O-CG 3.29Å; S794-L798 WeakPolarHBondContact O-CG 3.24Å; S794-L798 PolarHBondContact O-N 3.15Å; S794-V818 WeakPolarHBondContact OG-CG2 3.35Å
795E96.3Very high94Very high38 Ų3864.5 Ų64.518%0.17831%0.311CS..Hα-helixtrans-58.3-44.2177.1-173.5-172.5168.500111.6Y791 L798 R799 L815 V818 L819 Q822Y791-E795 WeakPolarHBondContact O-CB 3.32Å; Y791-E795 PolarHBondContact O-N 3.04Å; E795-L798 PolarHBondContact O-N 3.48Å; E795-R799 HydrophobicContact CG-CG 4.34Å; E795-R799 WeakPolarHBondContact O-CB 3.2Å; E795-R799 WeakPolarHBondContact O-CG 3.48Å; E795-R799 PolarHBondContact O-N 3.36Å; E795-R799 IonicContact OE1-CZ 2.73Å; E795-R799 VanDerWaalsContact OE1-CZ 3.29Å; E795-R799 IonicContact OE1-NE 3.58Å; E795-R799 PolarHBondContact OE1-NE 3.44Å; E795-R799 IonicContact OE1-NH2 2.82Å; E795-R799 PolarHBondContact OE1-NH2 2.98Å; E795-L815 HydrophobicContact CG-CD1 3.84Å; E795-V818 HydrophobicContact CB-CG1 4.09Å; E795-L819 HydrophobicContact CG-CD2 4.5Å; E795-Q822 PolarHBondContact OE2-NE2 2.93Å; E795-Q822 PolarHBondContact OE2-OE1 3.31Å
796K95.8Very high93.9Very high133 Ų13365.3 Ų65.358%0.57832%0.317SS*.Hα-helixtrans-58.8-51.6177.9-175.9-176.1175-174.70111.5S792 L793 S794 L798 R799 D800S792-K796 PolarHBondContact O-N 3Å; S792-K796 VanDerWaalsContact O-N 3.12Å; L793-K796 PolarHBondContact O-N 3.34Å; S794-K796 VanDerWaalsContact C-N 3.32Å; S794-K796 PolarHBondContact O-N 3.29Å; K796-L798 VanDerWaalsContact C-N 3.29Å; K796-L798 PolarHBondContact O-N 2.85Å; K796-R799 PolarHBondContact O-N 3.45Å; K796-D800 VanDerWaalsContact O-CG 3.27Å; K796-D800 PolarHBondContact O-N 2.95Å
797V95.8Very high93.8Very high28 Ų2864.9 Ų64.917%0.1732%0.317CS..Hα-helixtrans-60.5-41179.7172.60000111M778 L785 L793 S794 D800 A801M778-V797 HydrophobicContact CB-CG1 3.9Å; M778-V797 WeakPolarHBondContact CE-O 3.17Å; M778-V797 VanDerWaalsContact O-CG1 3.31Å; M778-V797 WeakPolarHBondContact O-CG1 3.44Å; L785-V797 HydrophobicContact CD1-CG2 4.19Å; L793-V797 WeakPolarHBondContact O-CG2 3.34Å; L793-V797 PolarHBondContact O-N 3.49Å; S794-V797 PolarHBondContact O-N 2.83Å; V797-D800 PolarHBondContact O-N 3.33Å; V797-A801 WeakPolarHBondContact O-CB 3.33Å; V797-A801 PolarHBondContact O-N 3.07Å
798L96.2Very high93.9Very high0 Ų060 Ų600%030%0.296CS..Hα-helixtrans-70.4-37.7178.9-68.4169.5000112.4S794 E795 K796 A801 V802 V811 L815 V818S794-L798 WeakPolarHBondContact O-CB 3.45Å; S794-L798 VanDerWaalsContact O-CG 3.29Å; S794-L798 WeakPolarHBondContact O-CG 3.24Å; S794-L798 PolarHBondContact O-N 3.15Å; E795-L798 PolarHBondContact O-N 3.48Å; K796-L798 VanDerWaalsContact C-N 3.29Å; K796-L798 PolarHBondContact O-N 2.85Å; L798-A801 WeakPolarHBondContact O-CB 3.48Å; L798-A801 PolarHBondContact O-N 2.99Å; L798-V802 WeakPolarHBondContact O-CG2 3.35Å; L798-V802 PolarHBondContact O-N 3.38Å; L798-V811 HydrophobicContact CD2-CG1 4.19Å; L798-V811 WeakPolarHBondContact O-CG1 3.41Å; L798-L815 HydrophobicContact CB-CB 4.29Å; L798-L815 HydrophobicContact CB-CD1 4.06Å; L798-L815 HydrophobicContact CD1-CB 4.4Å; L798-V818 HydrophobicContact CD1-CG2 3.82Å
799R94.9Very high94.1Very high123 Ų12358.4 Ų58.446%0.46429%0.287SS..Hα-helixtrans-65-39.8172.5-75.7-171.8-175.3-89.90.5111.9E795 K796 A801 V802 Q803 L815E795-R799 HydrophobicContact CG-CG 4.34Å; E795-R799 WeakPolarHBondContact O-CB 3.2Å; E795-R799 WeakPolarHBondContact O-CG 3.48Å; E795-R799 PolarHBondContact O-N 3.36Å; E795-R799 IonicContact OE1-CZ 2.73Å; E795-R799 VanDerWaalsContact OE1-CZ 3.29Å; E795-R799 IonicContact OE1-NE 3.58Å; E795-R799 PolarHBondContact OE1-NE 3.44Å; E795-R799 IonicContact OE1-NH2 2.82Å; E795-R799 PolarHBondContact OE1-NH2 2.98Å; K796-R799 PolarHBondContact O-N 3.45Å; R799-A801 VanDerWaalsContact C-N 3.28Å; R799-A801 PolarHBondContact O-N 3.11Å; R799-V802 PolarHBondContact O-N 3.37Å; R799-Q803 PolarHBondContact O-N 3.28Å; R799-Q803 VanDerWaalsContact O-N 3.08Å; R799-L815 HydrophobicContact CG-CD1 4.34Å; R799-L815 HydrophobicContact CG-CD2 4.42Å
800D93.7Very high94.1Very high76 Ų7655 Ų5541%0.40627%0.273SS..Hα-helixtrans-61.8-39.9173-67.7-18000110M778 K796 V797 V802 Q803 V804M778-D800 HydrophobicContact CE-CB 3.45Å; M778-D800 VanDerWaalsContact CE-CB 3.45Å; K796-D800 VanDerWaalsContact O-CG 3.27Å; K796-D800 PolarHBondContact O-N 2.95Å; V797-D800 PolarHBondContact O-N 3.33Å; D800-V802 PolarHBondContact O-N 3.26Å; D800-Q803 WeakPolarHBondContact O-CB 3.39Å; D800-Q803 PolarHBondContact O-N 3.14Å; D800-Q803 VanDerWaalsContact O-N 3.17Å; D800-V804 WeakPolarHBondContact O-CG2 3.36Å; D800-V804 PolarHBondContact O-N 3.31Å; D800-V804 VanDerWaalsContact O-N 3.16Å
801A94.6Very high94.2Very high0 Ų049 Ų490%025%0.251CS..Hα-helixtrans-64.2-37.5175.800000112.7M778 V797 L798 R799 Q803 V804 N805 V811M778-A801 HydrophobicContact CB-CB 3.75Å; M778-A801 HydrophobicContact CE-CB 4.01Å; M778-A801 VanDerWaalsContact CE-N 3.3Å; M778-A801 HydrophobicContact CG-CB 4.47Å; M778-A801 HydrophobicContact SD-CB 3.96Å; V797-A801 WeakPolarHBondContact O-CB 3.33Å; V797-A801 PolarHBondContact O-N 3.07Å; L798-A801 WeakPolarHBondContact O-CB 3.48Å; L798-A801 PolarHBondContact O-N 2.99Å; R799-A801 VanDerWaalsContact C-N 3.28Å; R799-A801 PolarHBondContact O-N 3.11Å; A801-Q803 VanDerWaalsContact C-N 3.34Å; A801-V804 PolarHBondContact O-N 2.95Å; A801-N805 PolarHBondContact O-N 3.26Å; A801-V811 HydrophobicContact CB-CG1 3.78Å; A801-V811 HydrophobicContact CB-CG2 4.13Å
802V93.9Very high94.3Very high11 Ų1147.2 Ų47.27%0.06724%0.244CC..Hα-helixtrans-64.4-35.6172.8170.60000111.9L798 R799 D800 V804 N805 S806 V811 W812 L815L798-V802 WeakPolarHBondContact O-CG2 3.35Å; L798-V802 PolarHBondContact O-N 3.38Å; R799-V802 PolarHBondContact O-N 3.37Å; D800-V802 PolarHBondContact O-N 3.26Å; V802-V804 VanDerWaalsContact C-N 3.33Å; V802-N805 CarbonylContact O-C 3.33Å; V802-S806 WeakPolarHBondContact O-CA 3.47Å; V802-S806 PolarHBondContact O-N 3.15Å; V802-S806 VanDerWaalsContact O-N 3.11Å; V802-V811 HydrophobicContact CG2-CG1 3.64Å; V802-W812 HydrophobicContact CG1-CH2 3.86Å; V802-W812 HydrophobicContact CG1-CZ2 3.44Å; V802-W812 VanDerWaalsContact CG1-CZ2 3.44Å; V802-W812 HydrophobicContact CG2-CD2 4.28Å; V802-W812 HydrophobicContact CG2-CH2 4.5Å; V802-W812 HydrophobicContact CG2-CZ2 4.22Å; V802-L815 HydrophobicContact CG2-CD2 4.41Å
803Q91.7Very high94.5Very high80 Ų8046 Ų4637%0.37423%0.231SC..Hα-helixtrans-66.1-38.2175.3-66.8-59-36.500111.7Q503 R799 D800 A801Q503-Q803 PolarHBondContact NE2-O 3.41Å; R799-Q803 PolarHBondContact O-N 3.28Å; R799-Q803 VanDerWaalsContact O-N 3.08Å; D800-Q803 WeakPolarHBondContact O-CB 3.39Å; D800-Q803 PolarHBondContact O-N 3.14Å; D800-Q803 VanDerWaalsContact O-N 3.17Å; A801-Q803 VanDerWaalsContact C-N 3.34Å
804V91Very high94.6Very high56 Ų5642.1 Ų42.134%0.33921%0.21SC..Hα-helixtrans-70.8-45.61771780000111.4T773 V775 D800 A801 V802T773-V804 HydrophobicContact CG2-CG2 4.19Å; T773-V804 WeakPolarHBondContact O-CG1 3.25Å; V775-V804 HydrophobicContact CG2-CB 4.01Å; V775-V804 HydrophobicContact CG2-CG1 3.53Å; D800-V804 WeakPolarHBondContact O-CG2 3.36Å; D800-V804 PolarHBondContact O-N 3.31Å; D800-V804 VanDerWaalsContact O-N 3.16Å; A801-V804 PolarHBondContact O-N 2.95Å; V802-V804 VanDerWaalsContact C-N 3.33Å
805N90.6Very high94.6Very high58 Ų5842.2 Ų42.231%0.3121%0.211SC..  trans-143.598.1177.4-177.15.2000111.6V775 A801 V802 T807 S808V775-N805 HydrophobicContact CG1-CB 4.34Å; V775-N805 HydrophobicContact CG2-CB 3.73Å; A801-N805 PolarHBondContact O-N 3.26Å; V802-N805 CarbonylContact O-C 3.33Å; N805-T807 PolarHBondContact O-N 2.87Å; N805-T807 PolarHBondContact OD1-N 3.37Å; N805-T807 PolarHBondContact OD1-OG1 3.04Å; N805-S808 PolarHBondContact O-N 3.36Å
806S91.6Very high94.6Very high27 Ų2740.4 Ų40.419%0.18920%0.202CC..THydrogen-bonded Turntrans-70.3-11.1178.560.50000113.9V802 W812 L838V802-S806 WeakPolarHBondContact O-CA 3.47Å; V802-S806 PolarHBondContact O-N 3.15Å; V802-S806 VanDerWaalsContact O-N 3.11Å; S806-W812 PolarHBondContact O-NE1 3.36Å; S806-L838 WeakPolarHBondContact O-CD1 3.21Å
807T92.4Very high94.6Very high33 Ų3337.2 Ų37.220%0.20219%0.19CC..THydrogen-bonded Turntrans-97.64.7-177.973.90000113.9R539 N805 H809R539-T807 PolarHBondContact NH2-O 3.4Å; R539-T807 PolarHBondContact NH2-OG1 2.93Å; N805-T807 PolarHBondContact O-N 2.87Å; N805-T807 PolarHBondContact OD1-N 3.37Å; N805-T807 PolarHBondContact OD1-OG1 3.04Å; T807-H809 PolarHBondContact O-N 2.9Å
808S94.3Very high94.6Very high16 Ų1636 Ų3611%0.11218%0.182CC..  trans-82.5100.5176.4-178.50000110.7N805 D810 V811 W812N805-S808 PolarHBondContact O-N 3.36Å; S808-D810 PolarHBondContact O-N 2.93Å; S808-V811 PolarHBondContact O-N 3.28Å; S808-V811 WeakPolarHBondContact OG-CG2 3.47Å; S808-W812 VanDerWaalsContact O-CD1 3.22Å; S808-W812 PolarHBondContact O-N 3.18Å
809H95.7Very high94.6Very high33 Ų3336 Ų3615%0.15318%0.182CC..Hα-helixtrans-59-37.8176.667.6-83.4000112.1T807 V811 W812 N813 A835 L838 E839T807-H809 PolarHBondContact O-N 2.9Å; H809-V811 VanDerWaalsContact C-N 3.33Å; H809-V811 PolarHBondContact O-N 3.47Å; H809-W812 PolarHBondContact O-N 3.25Å; H809-N813 PolarHBondContact O-N 3.48Å; H809-A835 HydrophobicContact CB-CB 4.37Å; H809-A835 VanDerWaalsContact CB-O 3.25Å; H809-A835 WeakPolarHBondContact CB-O 3.41Å; H809-A835 WeakPolarHBondContact O-CB 3.46Å; H809-L838 HydrophobicContact CB-CB 3.82Å; H809-E839 HydrophobicContact CB-CB 4.03Å; H809-E839 IonicContact CD2-OE2 3.89Å; H809-E839 PolarHBondContact CD2-OE2 2.83Å; H809-E839 IonicContact CE1-OE2 3.31Å; H809-E839 PolarHBondContact CE1-OE2 3.05Å; H809-E839 IonicContact CG-OE2 2.97Å; H809-E839 IonicContact ND1-OE2 2.86Å; H809-E839 PolarHBondContact ND1-OE2 3.39Å; H809-E839 VanDerWaalsContact ND1-OE2 3.12Å; H809-E839 IonicContact NE2-OE2 2.79Å; H809-E839 PolarHBondContact NE2-OE2 2.89Å
810D95.2Very high94.6Very high72 Ų7235.9 Ų35.939%0.38519%0.187SC..Hα-helixtrans-52.9-45.7175.6-81.5-46.4000113.3S808 N813 S814S808-D810 PolarHBondContact O-N 2.93Å; D810-N813 PolarHBondContact O-N 3.32Å; D810-S814 PolarHBondContact O-N 3.24Å; D810-S814 PolarHBondContact O-OG 3.07Å
811V96.5Very high94.6Very high0 Ų034.4 Ų34.40%019%0.185CC..Hα-helixtrans-69.1-42.7178.3174.50000110.7V775 Q779 L798 A801 V802 S808 H809 N813 S814 L815V775-V811 HydrophobicContact CG1-CG2 3.7Å; Q779-V811 HydrophobicContact CB-CG2 4.04Å; Q779-V811 HydrophobicContact CG-CG2 4.27Å; L798-V811 HydrophobicContact CD2-CG1 4.19Å; L798-V811 WeakPolarHBondContact O-CG1 3.41Å; A801-V811 HydrophobicContact CB-CG1 3.78Å; A801-V811 HydrophobicContact CB-CG2 4.13Å; V802-V811 HydrophobicContact CG2-CG1 3.64Å; S808-V811 PolarHBondContact O-N 3.28Å; S808-V811 WeakPolarHBondContact OG-CG2 3.47Å; H809-V811 VanDerWaalsContact C-N 3.33Å; H809-V811 PolarHBondContact O-N 3.47Å; V811-N813 VanDerWaalsContact C-N 3.32Å; V811-N813 PolarHBondContact O-N 2.88Å; V811-S814 PolarHBondContact O-N 3.48Å; V811-L815 WeakPolarHBondContact O-CB 3.45Å; V811-L815 PolarHBondContact O-N 3.05Å
812W97.2Very high94.5Very high34 Ų3438.1 Ų38.113%0.12920%0.203CC..Hα-helixtrans-62-40.2176-76.7110.2000112.1V802 S806 S808 H809 L815 G816 C831 T834 A835 L838V802-W812 HydrophobicContact CG1-CH2 3.86Å; V802-W812 HydrophobicContact CG1-CZ2 3.44Å; V802-W812 VanDerWaalsContact CG1-CZ2 3.44Å; V802-W812 HydrophobicContact CG2-CD2 4.28Å; V802-W812 HydrophobicContact CG2-CH2 4.5Å; V802-W812 HydrophobicContact CG2-CZ2 4.22Å; S806-W812 PolarHBondContact O-NE1 3.36Å; S808-W812 VanDerWaalsContact O-CD1 3.22Å; S808-W812 PolarHBondContact O-N 3.18Å; H809-W812 PolarHBondContact O-N 3.25Å; W812-L815 HydrophobicContact CE3-CD2 4.18Å; W812-L815 HydrophobicContact CZ3-CD2 4.16Å; W812-L815 PolarHBondContact O-N 3.4Å; W812-G816 PolarHBondContact O-N 2.99Å; W812-C831 HydrophobicContact CE3-CB 4.13Å; W812-C831 WeakPolarHBondContact O-CB 3.08Å; W812-T834 HydrophobicContact CD2-CG2 3.9Å; W812-T834 HydrophobicContact CE3-CG2 4.46Å; W812-T834 HydrophobicContact CG-CG2 4.05Å; W812-T834 HydrophobicContact CZ2-CG2 4.31Å; W812-A835 HydrophobicContact CB-CB 3.87Å; W812-L838 VanDerWaalsContact CD1-CD1 3.43Å; W812-L838 HydrophobicContact CG-CD1 4.47Å
813N96.6Very high94.4Very high63 Ų6340.7 Ų40.734%0.33723%0.231SC..Hα-helixtrans-63.8-48.3175.2-174.360.5000111.3H809 D810 V811 L815 G816 E817 F832 A835H809-N813 PolarHBondContact O-N 3.48Å; D810-N813 PolarHBondContact O-N 3.32Å; V811-N813 VanDerWaalsContact C-N 3.32Å; V811-N813 PolarHBondContact O-N 2.88Å; N813-L815 VanDerWaalsContact C-N 3.28Å; N813-L815 PolarHBondContact O-N 3.34Å; N813-G816 PolarHBondContact O-N 3.24Å; N813-G816 VanDerWaalsContact O-N 3.12Å; N813-E817 PolarHBondContact ND2-OE1 3.08Å; N813-E817 PolarHBondContact O-N 3.25Å; N813-F832 WeakPolarHBondContact O-CE1 3.33Å; N813-F832 WeakPolarHBondContact OD1-CD1 3.28Å; N813-F832 WeakPolarHBondContact OD1-CE1 3.41Å; N813-A835 HydrophobicContact CB-CB 4.16Å
814S96.5Very high94.6Very high3 Ų340.4 Ų40.42%0.02123%0.232CC..Hα-helixtrans-61-36.9176.8-59.70000112.1D810 V811 E817 V818D810-S814 PolarHBondContact O-N 3.24Å; D810-S814 PolarHBondContact O-OG 3.07Å; V811-S814 PolarHBondContact O-N 3.48Å; S814-E817 PolarHBondContact O-N 3.29Å; S814-V818 VanDerWaalsContact O-CG2 3.29Å; S814-V818 WeakPolarHBondContact O-CG2 3.29Å; S814-V818 PolarHBondContact O-N 3.45Å; S814-V818 VanDerWaalsContact O-N 3.16Å
815L96.4Very high94.7Very high3 Ų340.8 Ų40.82%0.01624%0.242CC..Hα-helixtrans-67.4-40.4175.6-178.261.3000111.3E795 L798 R799 V802 V811 W812 N813 V818 L819E795-L815 HydrophobicContact CG-CD1 3.84Å; L798-L815 HydrophobicContact CB-CB 4.29Å; L798-L815 HydrophobicContact CB-CD1 4.06Å; L798-L815 HydrophobicContact CD1-CB 4.4Å; R799-L815 HydrophobicContact CG-CD1 4.34Å; R799-L815 HydrophobicContact CG-CD2 4.42Å; V802-L815 HydrophobicContact CG2-CD2 4.41Å; V811-L815 WeakPolarHBondContact O-CB 3.45Å; V811-L815 PolarHBondContact O-N 3.05Å; W812-L815 HydrophobicContact CE3-CD2 4.18Å; W812-L815 HydrophobicContact CZ3-CD2 4.16Å; W812-L815 PolarHBondContact O-N 3.4Å; N813-L815 VanDerWaalsContact C-N 3.28Å; N813-L815 PolarHBondContact O-N 3.34Å; L815-V818 PolarHBondContact O-N 3.27Å; L815-L819 HydrophobicContact CD1-CD1 4.26Å; L815-L819 HydrophobicContact CD1-CG 4.3Å; L815-L819 HydrophobicContact CG-CD1 3.97Å; L815-L819 HydrophobicContact CG-CG 4.44Å; L815-L819 WeakPolarHBondContact O-CB 3.48Å; L815-L819 VanDerWaalsContact O-CG 3.27Å; L815-L819 WeakPolarHBondContact O-CG 3.38Å; L815-L819 PolarHBondContact O-N 3.43Å
816G96.3Very high94.8Very high0 Ų041.4 Ų41.40%025%0.254CS..Hα-helixtrans-59.3-45.517400000112.4W812 N813 V818 L819 Q820 A828W812-G816 PolarHBondContact O-N 2.99Å; N813-G816 PolarHBondContact O-N 3.24Å; N813-G816 VanDerWaalsContact O-N 3.12Å; G816-V818 PolarHBondContact O-N 3.16Å; G816-L819 PolarHBondContact O-N 2.84Å; G816-Q820 VanDerWaalsContact O-CB 3.3Å; G816-Q820 WeakPolarHBondContact O-CB 3.43Å; G816-Q820 PolarHBondContact O-N 2.91Å; G816-A828 WeakPolarHBondContact O-CB 3.41Å
817E95.8Very high94.9Very high66 Ų6641.1 Ų41.131%0.30825%0.254SS..Hα-helixtrans-58.9-45.3176-70.4172.7-165.300111.8N813 S814 Q820 A821 F832N813-E817 PolarHBondContact ND2-OE1 3.08Å; N813-E817 PolarHBondContact O-N 3.25Å; S814-E817 PolarHBondContact O-N 3.29Å; E817-Q820 PolarHBondContact O-N 3.11Å; E817-A821 WeakPolarHBondContact O-CB 3.42Å; E817-A821 PolarHBondContact O-N 3.09Å; E817-F832 HydrophobicContact CG-CE1 4.21Å; E817-F832 HydrophobicContact CG-CZ 4.29Å
818V96.3Very high95Very high1 Ų139.6 Ų39.61%0.00625%0.245CC..Hα-helixtrans-65.2-44.6178.5173.60000111.4H786 Y791 S794 E795 L798 S814 L815 G816 Q820 A821 Q822H786-V818 HydrophobicContact CB-CG2 3.87Å; Y791-V818 WeakPolarHBondContact O-CG1 3.41Å; S794-V818 WeakPolarHBondContact OG-CG2 3.35Å; E795-V818 HydrophobicContact CB-CG1 4.09Å; L798-V818 HydrophobicContact CD1-CG2 3.82Å; S814-V818 VanDerWaalsContact O-CG2 3.29Å; S814-V818 WeakPolarHBondContact O-CG2 3.29Å; S814-V818 PolarHBondContact O-N 3.45Å; S814-V818 VanDerWaalsContact O-N 3.16Å; L815-V818 PolarHBondContact O-N 3.27Å; G816-V818 PolarHBondContact O-N 3.16Å; V818-Q820 VanDerWaalsContact C-N 3.31Å; V818-Q820 PolarHBondContact O-N 3.01Å; V818-A821 PolarHBondContact O-N 2.91Å; V818-Q822 WeakPolarHBondContact O-CG 3.32Å; V818-Q822 PolarHBondContact O-N 3.14Å
819L95Very high95.1Very high2 Ų242.8 Ų42.81%0.0126%0.263CS..Hα-helixtrans-65.8-35.9178.1-72171.3000111.9E795 L815 G816 Q822 G823 N824 A827 A828E795-L819 HydrophobicContact CG-CD2 4.5Å; L815-L819 HydrophobicContact CD1-CD1 4.26Å; L815-L819 HydrophobicContact CD1-CG 4.3Å; L815-L819 HydrophobicContact CG-CD1 3.97Å; L815-L819 HydrophobicContact CG-CG 4.44Å; L815-L819 WeakPolarHBondContact O-CB 3.48Å; L815-L819 VanDerWaalsContact O-CG 3.27Å; L815-L819 WeakPolarHBondContact O-CG 3.38Å; L815-L819 PolarHBondContact O-N 3.43Å; G816-L819 PolarHBondContact O-N 2.84Å; L819-Q822 PolarHBondContact O-N 3.38Å; L819-G823 PolarHBondContact O-N 3.13Å; L819-N824 PolarHBondContact O-N 3.28Å; L819-A827 HydrophobicContact CD1-CB 3.94Å; L819-A828 HydrophobicContact CB-CB 4.05Å
820Q95Very high95.1Very high119 Ų11947.6 Ų47.656%0.55629%0.286SS*.Hα-helixtrans-64.6-44.4173.6-173.2176.917.500111G816 E817 V818 Q822 G823 A828G816-Q820 VanDerWaalsContact O-CB 3.3Å; G816-Q820 WeakPolarHBondContact O-CB 3.43Å; G816-Q820 PolarHBondContact O-N 2.91Å; E817-Q820 PolarHBondContact O-N 3.11Å; V818-Q820 VanDerWaalsContact C-N 3.31Å; V818-Q820 PolarHBondContact O-N 3.01Å; Q820-Q822 VanDerWaalsContact C-N 3.26Å; Q820-Q822 PolarHBondContact O-N 2.93Å; Q820-G823 PolarHBondContact O-N 2.97Å; Q820-A828 HydrophobicContact CB-CB 3.96Å
821A93.5Very high95.2Very high46 Ų4644.5 Ų44.538%0.3827%0.27SS..Hα-helixtrans-63.6-30.6175.900000113Y791 E817 V818 G823Y791-A821 HydrophobicContact CD1-CB 4.17Å; Y791-A821 HydrophobicContact CE1-CB 3.75Å; E817-A821 WeakPolarHBondContact O-CB 3.42Å; E817-A821 PolarHBondContact O-N 3.09Å; V818-A821 PolarHBondContact O-N 2.91Å; A821-G823 VanDerWaalsContact C-N 3.27Å; A821-G823 PolarHBondContact O-N 2.89Å
822Q93.5Very high95.2Very high78 Ų7847 Ų4736%0.36428%0.281SS..THydrogen-bonded Turntrans-77-8172.4-68.1177.6-1.200113.9Y791 E795 V818 L819 Q820Y791-Q822 HydrophobicContact CG-CG 4.23Å; Y791-Q822 PolarHBondContact O-NE2 2.99Å; E795-Q822 PolarHBondContact OE2-NE2 2.93Å; E795-Q822 PolarHBondContact OE2-OE1 3.31Å; V818-Q822 WeakPolarHBondContact O-CG 3.32Å; V818-Q822 PolarHBondContact O-N 3.14Å; L819-Q822 PolarHBondContact O-N 3.38Å; Q820-Q822 VanDerWaalsContact C-N 3.26Å; Q820-Q822 PolarHBondContact O-N 2.93Å
823G92.3Very high95.2Very high64 Ų6450.4 Ų50.466%0.6630%0.301SS*.THydrogen-bonded Turntrans87.66.7-178.400000115.2L819 Q820 A821 A825L819-G823 PolarHBondContact O-N 3.13Å; Q820-G823 PolarHBondContact O-N 2.97Å; A821-G823 VanDerWaalsContact C-N 3.27Å; A821-G823 PolarHBondContact O-N 2.89Å; G823-A825 PolarHBondContact O-N 3.07Å
824N94.2Very high95.1Very high74 Ų7449.2 Ų49.240%0.39630%0.296SS..  trans-89.770.9175.9-168.8-7.4000111.3L819 A826 A827 A828L819-N824 PolarHBondContact O-N 3.28Å; N824-A826 VanDerWaalsContact C-N 3.32Å; N824-A826 PolarHBondContact O-N 2.95Å; N824-A827 WeakPolarHBondContact ND2-CB 3Å; N824-A827 PolarHBondContact O-N 3.12Å; N824-A827 WeakPolarHBondContact OD1-CB 3.42Å; N824-A827 PolarHBondContact OD1-N 3.42Å; N824-A828 WeakPolarHBondContact O-CB 3.45Å; N824-A828 PolarHBondContact O-N 3.08Å; N824-A828 VanDerWaalsContact O-N 3.08Å
825A92.9Very high95.1Very high65 Ų6549.4 Ų49.454%0.53730%0.298SS..Hα-helixtrans-61.1-35.5-174.500000113.7G823 A828 T829G823-A825 PolarHBondContact O-N 3.07Å; A825-A828 PolarHBondContact O-N 3.45Å; A825-T829 WeakPolarHBondContact O-CG2 3.39Å; A825-T829 PolarHBondContact O-N 2.93Å; A825-T829 PolarHBondContact O-OG1 2.83Å
826A93.8Very high95.1Very high70 Ų7055.1 Ų55.158%0.57933%0.328SS*.Hα-helixtrans-65.9-50-17900000111.9N824 A828 T829 E830N824-A826 VanDerWaalsContact C-N 3.32Å; N824-A826 PolarHBondContact O-N 2.95Å; A826-A828 VanDerWaalsContact C-N 3.29Å; A826-A828 PolarHBondContact O-N 3.19Å; A826-T829 PolarHBondContact O-N 3.2Å; A826-T829 PolarHBondContact O-OG1 2.95Å; A826-E830 PolarHBondContact O-N 2.62Å; A826-E830 VanDerWaalsContact O-N 3.15Å
827A94.1Very high95.1Very high21 Ų2161.8 Ų61.817%0.17436%0.359CS..Hα-helixtrans-65.9-33.717700000111.9L819 N824 E830 C831L819-A827 HydrophobicContact CD1-CB 3.94Å; N824-A827 WeakPolarHBondContact ND2-CB 3Å; N824-A827 PolarHBondContact O-N 3.12Å; N824-A827 WeakPolarHBondContact OD1-CB 3.42Å; N824-A827 PolarHBondContact OD1-N 3.42Å; A827-E830 PolarHBondContact O-N 3.05Å; A827-C831 PolarHBondContact O-N 3.15Å; A827-C831 PolarHBondContact O-SG 3.24Å
828A94.9Very high95Very high2 Ų259.9 Ų59.92%0.01735%0.351CS..Hα-helixtrans-61.7-45.7173.300000111.8G816 L819 Q820 N824 A825 A826 E830 C831 F832G816-A828 WeakPolarHBondContact O-CB 3.41Å; L819-A828 HydrophobicContact CB-CB 4.05Å; Q820-A828 HydrophobicContact CB-CB 3.96Å; N824-A828 WeakPolarHBondContact O-CB 3.45Å; N824-A828 PolarHBondContact O-N 3.08Å; N824-A828 VanDerWaalsContact O-N 3.08Å; A825-A828 PolarHBondContact O-N 3.45Å; A826-A828 VanDerWaalsContact C-N 3.29Å; A826-A828 PolarHBondContact O-N 3.19Å; A828-E830 VanDerWaalsContact C-N 3.32Å; A828-E830 PolarHBondContact O-N 3.39Å; A828-C831 WeakPolarHBondContact O-CB 3.36Å; A828-C831 PolarHBondContact O-N 2.91Å; A828-C831 VanDerWaalsContact O-N 3.17Å; A828-F832 HydrophobicContact CB-CE2 4.1Å; A828-F832 WeakPolarHBondContact O-CD2 3.34Å; A828-F832 WeakPolarHBondContact O-CG 3.25Å; A828-F832 PolarHBondContact O-N 3.03Å
829T95.6Very high95Very high82 Ų8262.9 Ų62.950%0.50337%0.365SS..Hα-helixtrans-61.1-39.3176.851.20000112.8A825 A826 F832 L833A825-T829 WeakPolarHBondContact O-CG2 3.39Å; A825-T829 PolarHBondContact O-N 2.93Å; A825-T829 PolarHBondContact O-OG1 2.83Å; A826-T829 PolarHBondContact O-N 3.2Å; A826-T829 PolarHBondContact O-OG1 2.95Å; T829-F832 PolarHBondContact O-N 3.14Å; T829-L833 VanDerWaalsContact O-CG 3.3Å; T829-L833 WeakPolarHBondContact O-CG 3.43Å; T829-L833 PolarHBondContact O-N 3.42Å
830E96Very high95Very high134 Ų13466.3 Ų66.363%0.62639%0.393SS*.Hα-helixtrans-63.3-41.8174.9-171.7-178.4179.500111.7A826 A827 A828 L833 T834A826-E830 PolarHBondContact O-N 2.62Å; A826-E830 VanDerWaalsContact O-N 3.15Å; A827-E830 PolarHBondContact O-N 3.05Å; A828-E830 VanDerWaalsContact C-N 3.32Å; A828-E830 PolarHBondContact O-N 3.39Å; E830-L833 PolarHBondContact O-N 2.91Å; E830-T834 WeakPolarHBondContact O-CB 3.24Å; E830-T834 PolarHBondContact O-N 3.34Å; E830-T834 PolarHBondContact O-OG1 3.38Å
831C96.3Very high95Very high8 Ų861.5 Ų61.55%0.05437%0.373CS..Hα-helixtrans-63.5-43.9176.1-67.10000112W812 A827 A828 T834 A835W812-C831 HydrophobicContact CE3-CB 4.13Å; W812-C831 WeakPolarHBondContact O-CB 3.08Å; A827-C831 PolarHBondContact O-N 3.15Å; A827-C831 PolarHBondContact O-SG 3.24Å; A828-C831 WeakPolarHBondContact O-CB 3.36Å; A828-C831 PolarHBondContact O-N 2.91Å; A828-C831 VanDerWaalsContact O-N 3.17Å; C831-T834 PolarHBondContact O-N 3.36Å; C831-A835 WeakPolarHBondContact O-CB 3.34Å; C831-A835 PolarHBondContact O-N 3.39Å
832F96.8Very high95.1Very high51 Ų5160.1 Ų60.122%0.22436%0.36CS..Hα-helixtrans-66-40.6177.7-65.4-46.9000112.5N813 E817 A828 T829 A835 L836N813-F832 WeakPolarHBondContact O-CE1 3.33Å; N813-F832 WeakPolarHBondContact OD1-CD1 3.28Å; N813-F832 WeakPolarHBondContact OD1-CE1 3.41Å; E817-F832 HydrophobicContact CG-CE1 4.21Å; E817-F832 HydrophobicContact CG-CZ 4.29Å; A828-F832 HydrophobicContact CB-CE2 4.1Å; A828-F832 WeakPolarHBondContact O-CD2 3.34Å; A828-F832 WeakPolarHBondContact O-CG 3.25Å; A828-F832 PolarHBondContact O-N 3.03Å; T829-F832 PolarHBondContact O-N 3.14Å; F832-A835 PolarHBondContact O-N 3.37Å; F832-L836 WeakPolarHBondContact O-CG 3.49Å; F832-L836 PolarHBondContact O-N 2.78Å
833L96.6Very high95.2Very high107 Ų10757 Ų5756%0.5635%0.347SS*.Hα-helixtrans-60.9-46.8174.2-72.5172.3000111.1T829 E830 A835 L836 E837T829-L833 VanDerWaalsContact O-CG 3.3Å; T829-L833 WeakPolarHBondContact O-CG 3.43Å; T829-L833 PolarHBondContact O-N 3.42Å; E830-L833 PolarHBondContact O-N 2.91Å; L833-A835 VanDerWaalsContact C-N 3.3Å; L833-A835 PolarHBondContact O-N 3.5Å; L833-L836 PolarHBondContact O-N 3.2Å; L833-E837 WeakPolarHBondContact O-CG 3.37Å; L833-E837 PolarHBondContact O-N 3.13Å
834T95.8Very high95.4Very high37 Ų3755.6 Ų55.623%0.22732%0.324CS..Hα-helixtrans-59.8-41.3175.9-550000111.5W812 E830 C831 E837 L838W812-T834 HydrophobicContact CD2-CG2 3.9Å; W812-T834 HydrophobicContact CE3-CG2 4.46Å; W812-T834 HydrophobicContact CG-CG2 4.05Å; W812-T834 HydrophobicContact CZ2-CG2 4.31Å; E830-T834 WeakPolarHBondContact O-CB 3.24Å; E830-T834 PolarHBondContact O-N 3.34Å; E830-T834 PolarHBondContact O-OG1 3.38Å; C831-T834 PolarHBondContact O-N 3.36Å; T834-E837 PolarHBondContact O-N 3.13Å; T834-L838 HydrophobicContact CG2-CD1 3.9Å; T834-L838 HydrophobicContact CG2-CG 4.46Å; T834-L838 WeakPolarHBondContact O-CB 3.49Å; T834-L838 VanDerWaalsContact O-CG 3.28Å; T834-L838 WeakPolarHBondContact O-CG 3.46Å; T834-L838 PolarHBondContact O-N 3.12Å
835A96.5Very high95.4Very high7 Ų753.1 Ų53.16%0.05831%0.311CS..Hα-helixtrans-62-44.3176.400000111.9H809 W812 N813 C831 F832 L833 L838 E839H809-A835 HydrophobicContact CB-CB 4.37Å; H809-A835 VanDerWaalsContact CB-O 3.25Å; H809-A835 WeakPolarHBondContact CB-O 3.41Å; H809-A835 WeakPolarHBondContact O-CB 3.46Å; W812-A835 HydrophobicContact CB-CB 3.87Å; N813-A835 HydrophobicContact CB-CB 4.16Å; C831-A835 WeakPolarHBondContact O-CB 3.34Å; C831-A835 PolarHBondContact O-N 3.39Å; F832-A835 PolarHBondContact O-N 3.37Å; L833-A835 VanDerWaalsContact C-N 3.3Å; L833-A835 PolarHBondContact O-N 3.5Å; A835-L838 PolarHBondContact O-N 3.36Å; A835-E839 VanDerWaalsContact O-CB 3.3Å; A835-E839 WeakPolarHBondContact O-CB 3.43Å; A835-E839 PolarHBondContact O-N 2.65Å
836L96.3Very high95.5Very high123 Ų12353.9 Ų53.964%0.64431%0.31SS*.Hα-helixtrans-64.4-42.5178.5-70.8171.3000112.4F832 L833 E839 A840F832-L836 WeakPolarHBondContact O-CG 3.49Å; F832-L836 PolarHBondContact O-N 2.78Å; L833-L836 PolarHBondContact O-N 3.2Å; L836-E839 PolarHBondContact O-N 3.06Å; L836-A840 WeakPolarHBondContact O-CB 3.46Å; L836-A840 PolarHBondContact O-N 3.12Å; L836-A840 VanDerWaalsContact O-N 3.09Å
837E95Very high95.6Very high141 Ų14151 Ų5166%0.65928%0.284SS*.Hα-helixtrans-62.1-42.8176.4-71.6177.4-176.200112L833 T834 S841L833-E837 WeakPolarHBondContact O-CG 3.37Å; L833-E837 PolarHBondContact O-N 3.13Å; T834-E837 PolarHBondContact O-N 3.13Å; E837-S841 PolarHBondContact O-OG 3Å
838L95.6Very high95.6Very high25 Ų2553 Ų5313%0.13130%0.295CS..Hα-helixtrans-71.6-35.8178.4-71.5172.5000112.5S806 H809 W812 T834 A835 S841 S842S806-L838 WeakPolarHBondContact O-CD1 3.21Å; H809-L838 HydrophobicContact CB-CB 3.82Å; W812-L838 VanDerWaalsContact CD1-CD1 3.43Å; W812-L838 HydrophobicContact CG-CD1 4.47Å; T834-L838 HydrophobicContact CG2-CD1 3.9Å; T834-L838 HydrophobicContact CG2-CG 4.46Å; T834-L838 WeakPolarHBondContact O-CB 3.49Å; T834-L838 VanDerWaalsContact O-CG 3.28Å; T834-L838 WeakPolarHBondContact O-CG 3.46Å; T834-L838 PolarHBondContact O-N 3.12Å; A835-L838 PolarHBondContact O-N 3.36Å; L838-S841 CarbonylContact O-C 3.58Å; L838-S841 PolarHBondContact O-N 3.39Å; L838-S841 PolarHBondContact O-OG 3.4Å; L838-S842 PolarHBondContact O-N 3.17Å; L838-S842 VanDerWaalsContact O-N 3.11Å
839E95.4Very high95.6Very high65 Ų6555.8 Ų55.830%0.30431%0.309SS..Hα-helixtrans-67.1-38.1178.117747.2-151.800111.9K573 H809 A835 L836 S841 S842K573-E839 WeakPolarHBondContact CE-O 3.31Å; K573-E839 PolarHBondContact NZ-O 2.85Å; K573-E839 VanDerWaalsContact NZ-O 3.07Å; K573-E839 IonicContact NZ-OE1 2.67Å; K573-E839 PolarHBondContact NZ-OE1 2.86Å; K573-E839 IonicContact NZ-OE2 3.48Å; H809-E839 HydrophobicContact CB-CB 4.03Å; H809-E839 IonicContact CD2-OE2 3.89Å; H809-E839 PolarHBondContact CD2-OE2 2.83Å; H809-E839 IonicContact CE1-OE2 3.31Å; H809-E839 PolarHBondContact CE1-OE2 3.05Å; H809-E839 IonicContact CG-OE2 2.97Å; H809-E839 IonicContact ND1-OE2 2.86Å; H809-E839 PolarHBondContact ND1-OE2 3.39Å; H809-E839 VanDerWaalsContact ND1-OE2 3.12Å; H809-E839 IonicContact NE2-OE2 2.79Å; H809-E839 PolarHBondContact NE2-OE2 2.89Å; A835-E839 VanDerWaalsContact O-CB 3.3Å; A835-E839 WeakPolarHBondContact O-CB 3.43Å; A835-E839 PolarHBondContact O-N 2.65Å; L836-E839 PolarHBondContact O-N 3.06Å; E839-S841 PolarHBondContact O-N 3.42Å; E839-S841 VanDerWaalsContact O-N 3.11Å; E839-S842 WeakPolarHBondContact O-CB 3.38Å; E839-S842 PolarHBondContact O-N 2.86Å; E839-S842 VanDerWaalsContact OE2-CB 3.29Å; E839-S842 WeakPolarHBondContact OE2-CB 3.35Å
840A94.7Very high95.6Very high73 Ų7351.9 Ų51.960%0.60329%0.285SS*.THydrogen-bonded Turntrans-60.4-20.5175.300000113.7L836L836-A840 WeakPolarHBondContact O-CB 3.46Å; L836-A840 PolarHBondContact O-N 3.12Å; L836-A840 VanDerWaalsContact O-N 3.09Å
841S94.9Very high95.4Very high18 Ų1848.5 Ų48.513%0.12627%0.274CS..THydrogen-bonded Turntrans-117.516.5177.562.50000113R539 E837 L838 E839 P843R539-S841 PolarHBondContact NH1-O 2.96Å; E837-S841 PolarHBondContact O-OG 3Å; L838-S841 CarbonylContact O-C 3.58Å; L838-S841 PolarHBondContact O-N 3.39Å; L838-S841 PolarHBondContact O-OG 3.4Å; E839-S841 PolarHBondContact O-N 3.42Å; E839-S841 VanDerWaalsContact O-N 3.11Å; S841-P843 WeakPolarHBondContact O-CD 3.46Å
842S95.8Very high95.3Very high18 Ų1849.6 Ų49.613%0.12628%0.277CS..  trans-82.5114.8-176.3-166.10000112.6A571 K573 L838 E839A571-S842 WeakPolarHBondContact CA-O 3.34Å; K573-S842 PolarHBondContact NZ-O 3.09Å; K573-S842 VanDerWaalsContact NZ-O 3.17Å; L838-S842 PolarHBondContact O-N 3.17Å; L838-S842 VanDerWaalsContact O-N 3.11Å; E839-S842 WeakPolarHBondContact O-CB 3.38Å; E839-S842 PolarHBondContact O-N 2.86Å; E839-S842 VanDerWaalsContact OE2-CB 3.29Å; E839-S842 WeakPolarHBondContact OE2-CB 3.35Å
843P96.6Very high95.1Very high11 Ų1149.3 Ų49.37%0.07128%0.284CS..  trans-73.6159.9173.834.3-36.9000110.7A571 S841 L845 F847A571-P843 HydrophobicContact CB-CB 4.09Å; S841-P843 WeakPolarHBondContact O-CD 3.46Å; P843-L845 VanDerWaalsContact CB-O 3.3Å; P843-L845 WeakPolarHBondContact CB-O 3.33Å; P843-L845 WeakPolarHBondContact CG-O 3.41Å; P843-L845 PolarHBondContact O-N 2.72Å; P843-F847 HydrophobicContact CB-CD1 4.42Å; P843-F847 HydrophobicContact CB-CE1 3.82Å; P843-F847 HydrophobicContact CB-CE2 4.27Å; P843-F847 HydrophobicContact CB-CZ 3.73Å; P843-F847 HydrophobicContact CG-CD1 4.38Å; P843-F847 HydrophobicContact CG-CD2 4.06Å; P843-F847 HydrophobicContact CG-CE1 4.06Å; P843-F847 HydrophobicContact CG-CE2 3.7Å; P843-F847 HydrophobicContact CG-CG 4.39Å; P843-F847 HydrophobicContact CG-CZ 3.7Å
844I94.9Very high94.5Very high35 Ų3547.1 Ų47.118%0.17927%0.273CS..SBendtrans-62.7-32.5179.7-165.464000113.1L567 S570 Y575 T598 K601 L602 M605L567-I844 HydrophobicContact CD2-CG2 4.09Å; S570-I844 PolarHBondContact OG-N 2.71Å; Y575-I844 HydrophobicContact CE1-CD1 4.5Å; T598-I844 HydrophobicContact CG2-CG2 4.19Å; K601-I844 HydrophobicContact CB-CG1 3.71Å; L602-I844 HydrophobicContact CD2-CB 4.21Å; L602-I844 HydrophobicContact CD2-CG1 4.29Å; L602-I844 HydrophobicContact CD2-CG2 3.92Å; L602-I844 HydrophobicContact CG-CG2 4.15Å; M605-I844 HydrophobicContact CG-CD1 3.44Å; M605-I844 VanDerWaalsContact CG-CD1 3.44Å; M605-I844 HydrophobicContact SD-CD1 4.34Å
845L94.8Very high94.5Very high23 Ų2347.6 Ų47.612%0.1228%0.275CS..SBendtrans-133150.8171.5-75179.2000109.2L567 T598 K601 P843 F847L567-L845 HydrophobicContact CD2-CB 4.03Å; T598-L845 HydrophobicContact CG2-CD1 4.46Å; K601-L845 HydrophobicContact CB-CG 4.44Å; K601-L845 HydrophobicContact CD-CD2 4.47Å; K601-L845 HydrophobicContact CG-CD1 4.14Å; K601-L845 HydrophobicContact CG-CD2 3.92Å; K601-L845 HydrophobicContact CG-CG 4.01Å; P843-L845 VanDerWaalsContact CB-O 3.3Å; P843-L845 WeakPolarHBondContact CB-O 3.33Å; P843-L845 WeakPolarHBondContact CG-O 3.41Å; P843-L845 PolarHBondContact O-N 2.72Å; L845-F847 PolarHBondContact O-N 3.28Å
846P95.1Very high94.4Very high81 Ų8149.7 Ų49.753%0.52629%0.286SS..  trans-56.5136.8178.9-23.633.5000111.9T848 I849P846-T848 PolarHBondContact O-N 2.89Å; P846-T848 VanDerWaalsContact O-N 3.09Å; P846-I849 WeakPolarHBondContact O-CB 3.48Å; P846-I849 WeakPolarHBondContact O-CG2 3.22Å; P846-I849 PolarHBondContact O-N 3.05Å
847F96.7Very high94.3Very high8 Ų845.7 Ų45.74%0.03527%0.267CS..G310 helixtrans-56-29.5176.7-62.3-62000113L533 A536 V537 I541 L564 L567 L568 A571 P843 L845 I849 I850L533-F847 HydrophobicContact CD1-CB 4.09Å; A536-F847 VanDerWaalsContact C-CD2 3.48Å; A536-F847 HydrophobicContact CB-CB 4.44Å; A536-F847 HydrophobicContact CB-CD1 3.87Å; A536-F847 HydrophobicContact CB-CD2 3.85Å; A536-F847 HydrophobicContact CB-CE1 3.99Å; A536-F847 HydrophobicContact CB-CE2 3.97Å; A536-F847 HydrophobicContact CB-CG 3.79Å; A536-F847 HydrophobicContact CB-CZ 4.05Å; A536-F847 VanDerWaalsContact O-CD2 3.25Å; A536-F847 WeakPolarHBondContact O-CD2 3.33Å; A536-F847 WeakPolarHBondContact O-CE2 3.49Å; V537-F847 HydrophobicContact CG2-CB 4.11Å; I541-F847 HydrophobicContact CD1-CE2 4.22Å; I541-F847 HydrophobicContact CD1-CZ 3.96Å; L564-F847 HydrophobicContact CD1-CD1 3.75Å; L564-F847 HydrophobicContact CD1-CE1 4.32Å; L567-F847 HydrophobicContact CB-CD1 3.82Å; L567-F847 HydrophobicContact CB-CE1 3.76Å; L567-F847 HydrophobicContact CD1-CD1 4.24Å; L568-F847 HydrophobicContact CD2-CE1 3.89Å; L568-F847 HydrophobicContact CD2-CZ 3.97Å; L568-F847 HydrophobicContact CG-CE1 4.16Å; A571-F847 HydrophobicContact CB-CZ 4.11Å; P843-F847 HydrophobicContact CB-CD1 4.42Å; P843-F847 HydrophobicContact CB-CE1 3.82Å; P843-F847 HydrophobicContact CB-CE2 4.27Å; P843-F847 HydrophobicContact CB-CZ 3.73Å; P843-F847 HydrophobicContact CG-CD1 4.38Å; P843-F847 HydrophobicContact CG-CD2 4.06Å; P843-F847 HydrophobicContact CG-CE1 4.06Å; P843-F847 HydrophobicContact CG-CE2 3.7Å; P843-F847 HydrophobicContact CG-CG 4.39Å; P843-F847 HydrophobicContact CG-CZ 3.7Å; L845-F847 PolarHBondContact O-N 3.28Å; F847-I849 PolarHBondContact O-N 3.42Å; F847-I849 VanDerWaalsContact O-N 3.11Å; F847-I850 PolarHBondContact O-N 3.34Å
848T93.9Very high94.2Very high65 Ų6540.1 Ų40.140%0.39924%0.243SC..G310 helixtrans-70.20.9177.7590000114.2V537 P846 I850V537-T848 HydrophobicContact CG2-CG2 4.1Å; P846-T848 PolarHBondContact O-N 2.89Å; P846-T848 VanDerWaalsContact O-N 3.09Å; T848-I850 PolarHBondContact O-N 3.48Å
849I94.1Very high94.1Very high60 Ų6041 Ų4131%0.30825%0.251SS..G310 helixtrans-63.3-28.2167.6-167.759.4000111.4L567 P846 F847L567-I849 HydrophobicContact CD1-CG2 3.8Å; P846-I849 WeakPolarHBondContact O-CB 3.48Å; P846-I849 WeakPolarHBondContact O-CG2 3.22Å; P846-I849 PolarHBondContact O-N 3.05Å; F847-I849 PolarHBondContact O-N 3.42Å; F847-I849 VanDerWaalsContact O-N 3.11Å
850I95.5Very high94.1Very high0 Ų039.4 Ų39.40%025%0.247CC..SBendtrans-79122.9176-54.8171000108.2F529 L533 H560 H563 L564 L567 F847 T848F529-I850 HydrophobicContact CE1-CG2 4.47Å; F529-I850 HydrophobicContact CZ-CG2 3.72Å; L533-I850 HydrophobicContact CD1-CD1 4.45Å; H560-I850 HydrophobicContact CB-CG2 3.93Å; H563-I850 HydrophobicContact CB-CD1 4.1Å; H563-I850 HydrophobicContact CB-CG1 4.47Å; L564-I850 HydrophobicContact CB-CD1 3.67Å; L564-I850 HydrophobicContact CD1-CD1 4.21Å; L564-I850 HydrophobicContact CG-CD1 4.47Å; L567-I850 HydrophobicContact CD1-CD1 4.11Å; L567-I850 HydrophobicContact CD1-CG1 4.41Å; F847-I850 PolarHBondContact O-N 3.34Å; T848-I850 PolarHBondContact O-N 3.48Å
851P92.9Very high94Very high62 Ų6237 Ų3740%0.40322%0.222SC..  trans-64.8138.5-175.725.7-34.5000111.5
852R94.4Very high93.9Very high31 Ų3138.5 Ų38.512%0.11723%0.229CC..  trans-96.390175.1-70.2169.4-73.4176.4-1109L488 S491 L492 T495 Y530 L533L488-R852 HydrophobicContact CD2-CB 3.91Å; L488-R852 HydrophobicContact CD2-CG 4.44Å; S491-R852 PolarHBondContact O-NH1 3.45Å; S491-R852 WeakPolarHBondContact OG-CD 3.47Å; S491-R852 PolarHBondContact OG-NH1 3.1Å; L492-R852 HydrophobicContact CD2-CB 4.22Å; L492-R852 HydrophobicContact CG-CB 4.39Å; T495-R852 PolarHBondContact OG1-NH1 3.11Å; T495-R852 PolarHBondContact OG1-NH2 2.77Å; Y530-R852 HydrophobicContact CE1-CG 4.48Å; L533-R852 HydrophobicContact CD2-CG 3.98Å
853A90.8Very high93.8Very high45 Ų4540.2 Ų40.237%0.37224%0.237SC..  trans-134.7156.1-173.300000112.8Y530Y530-A853 PolarHBondContact OH-N 2.87Å; Y530-A853 VanDerWaalsContact OH-N 3.07Å; Y530-A853 PolarHBondContact OH-O 2.92Å
854L85.8Confident93.5Very high61 Ų6142.8 Ų42.832%0.31925%0.253SS..  trans-95.20176.4-84168.4000113.3V448 K449 I452 L484 A485 L488V448-L854 HydrophobicContact CB-CD1 3.76Å; V448-L854 HydrophobicContact CG1-CD1 3.46Å; V448-L854 VanDerWaalsContact CG1-CD1 3.46Å; K449-L854 HydrophobicContact CB-CB 3.98Å; K449-L854 WeakPolarHBondContact CD-O 3.36Å; K449-L854 VanDerWaalsContact CE-O 3.23Å; K449-L854 WeakPolarHBondContact CE-O 2.93Å; K449-L854 HydrophobicContact CG-CB 4.25Å; K449-L854 WeakPolarHBondContact CG-O 3.37Å; K449-L854 PolarHBondContact NZ-O 3.2Å; I452-L854 HydrophobicContact CD1-CB 4.04Å; I452-L854 HydrophobicContact CD1-CD1 3.76Å; I452-L854 HydrophobicContact CD1-CG 3.69Å; L484-L854 HydrophobicContact CD2-CD2 4.37Å; A485-L854 HydrophobicContact CB-CD1 3.65Å; A485-L854 HydrophobicContact CB-CD2 4.16Å; A485-L854 HydrophobicContact CB-CG 4.46Å; L488-L854 HydrophobicContact CD1-CD2 3.71Å; L488-L854 HydrophobicContact CD1-CG 3.63Å

Retrieved 854 of 854 residues in 2218.5 ms (Link to these results)