A0A087Y8K5_POEFO Loading...

phosphopyruvate hydratase

AlphaFold DB , UniProt , Accession A0A087Y8K5, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 433 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1T59Low91.3Very high156 Ų15656.7 Ų56.796%0.95729%0.29SS*.  0116.5020.20000108
2M71.6Confident91.9Very high44 Ų4454.1 Ų54.122%0.21728%0.276CS..PPolyproline II helixtrans-77.4135.2175.5-67.9-166.1-152.300111.3K28 K29 S84 V85 E126M2-K28 HydrophobicContact CE-CB 4.32Å; M2-K28 HydrophobicContact SD-CB 3.57Å; M2-K28 VanDerWaalsContact SD-CB 3.57Å; M2-K28 HydrophobicContact SD-CD 4.48Å; M2-K28 HydrophobicContact SD-CG 4.24Å; M2-K29 HydrophobicContact CE-CD 3.78Å; M2-K29 VanDerWaalsContact CE-CE 3.48Å; M2-K29 HydrophobicContact CE-CG 3.81Å; M2-K29 HydrophobicContact SD-CD 4.4Å; M2-K29 HydrophobicContact SD-CG 3.78Å; M2-S84 WeakPolarHBondContact O-CA 3.49Å; M2-S84 PolarHBondContact O-OG 3.01Å; M2-S84 VanDerWaalsContact O-OG 3.13Å; M2-V85 PolarHBondContact O-N 3.39Å; M2-E126 WeakPolarHBondContact CB-OE1 3.04Å; M2-E126 WeakPolarHBondContact CB-OE2 3.48Å; M2-E126 WeakPolarHBondContact CE-OE2 3.47Å; M2-E126 WeakPolarHBondContact CG-OE1 3.47Å; M2-E126 WeakPolarHBondContact CG-OE2 3.11Å; M2-E126 PolarHBondContact N-OE1 3.13Å
3S87.1Confident92.4Very high29 Ų2957.8 Ų57.820%0.20329%0.29CS..BIsolated β-bridgetrans-100.5167.6173.852.50000112L5 D82S3-L5 PolarHBondContact O-N 2.85Å; S3-D82 WeakPolarHBondContact CB-OD1 3.48Å; S3-D82 PolarHBondContact OG-OD1 2.74Å
4I97.1Very high92.8Very high6 Ų654.4 Ų54.43%0.03127%0.273CS..PPolyproline II helixtrans-73.1122.4179.9-58.6170000109I7 L25 L78 V79 V85 I91I4-I7 HydrophobicContact CD1-CD1 4.4Å; I4-I7 HydrophobicContact CG2-CD1 3.87Å; I4-I7 HydrophobicContact CG2-CG1 3.66Å; I4-L25 HydrophobicContact CD1-CD1 4.19Å; I4-L25 HydrophobicContact CG1-CD1 4.22Å; I4-L25 HydrophobicContact CG1-CD2 4.47Å; I4-L25 HydrophobicContact CG2-CD1 4.31Å; I4-L25 HydrophobicContact CG2-CD2 4.43Å; I4-L25 HydrophobicContact CG2-CG 4.12Å; I4-L78 HydrophobicContact CD1-CB 4.19Å; I4-V79 HydrophobicContact CG2-CG2 3.91Å; I4-V85 HydrophobicContact CD1-CG1 4.37Å; I4-V85 HydrophobicContact CG1-CG1 3.57Å; I4-I91 HydrophobicContact CD1-CD1 4.25Å
5L97.1Very high93.1Very high92 Ų9252.5 Ų52.548%0.48227%0.267SS..  trans-88.8-38178.6-59.5178.7000112.3S3 Y26 K28S3-L5 PolarHBondContact O-N 2.85Å; L5-Y26 WeakPolarHBondContact CB-O 3.48Å; L5-Y26 PolarHBondContact N-O 2.87Å; L5-K28 HydrophobicContact CD1-CG 4.03Å
6K98.1Very high93.3Very high111 Ų11153.3 Ų53.348%0.48327%0.265SS..EExtended strand (participates in β ladder)trans-158.6145.9-178.4-178.6179.6179.2-175.90109.5Y26K6-Y26 HydrophobicContact CB-CD2 3.86Å; K6-Y26 HydrophobicContact CB-CG 4.25Å; K6-Y26 HydrophobicContact CD-CD2 4.14Å; K6-Y26 HydrophobicContact CD-CE2 4.24Å; K6-Y26 HydrophobicContact CG-CD2 4.05Å; K6-Y26 HydrophobicContact CG-CE2 4.47Å; K6-Y26 PolarHBondContact O-N 3.45Å
7I98.8Very high93.5Very high9 Ų952.8 Ų52.85%0.04628%0.277CS..EExtended strand (participates in β ladder)trans-124.1139.3164.1-64.6168.1000107I4 V23 D24 L25 I70 A75 L78 V115I4-I7 HydrophobicContact CD1-CD1 4.4Å; I4-I7 HydrophobicContact CG2-CD1 3.87Å; I4-I7 HydrophobicContact CG2-CG1 3.66Å; I7-V23 HydrophobicContact CG2-CG1 3.68Å; I7-D24 CarbonylContact C-O 3.6Å; I7-D24 WeakPolarHBondContact CA-O 3.33Å; I7-L25 HydrophobicContact CD1-CD1 4.18Å; I7-L25 HydrophobicContact CG1-CB 4.4Å; I7-L25 HydrophobicContact CG1-CD1 4.06Å; I7-L25 HydrophobicContact CG1-CG 3.99Å; I7-I70 HydrophobicContact CG2-CG2 3.75Å; I7-A75 HydrophobicContact CB-CB 3.64Å; I7-A75 HydrophobicContact CG2-CB 4.07Å; I7-L78 HydrophobicContact CD1-CB 4.22Å; I7-L78 HydrophobicContact CD1-CD1 3.91Å; I7-V115 HydrophobicContact CD1-CG1 4.03Å; I7-V115 HydrophobicContact CG2-CG2 4.35Å
8H98.8Very high93.7Very high66 Ų6651.2 Ų51.231%0.30627%0.269SS..EExtended strand (participates in β ladder)trans-142127.8173.9177.751.6000110.3R10 D24 N71H8-R10 PolarHBondContact CD2-NH2 2.97Å; H8-R10 VanDerWaalsContact CD2-NH2 3.35Å; H8-D24 PolarHBondContact N-O 3.2Å; H8-D24 PolarHBondContact O-N 2.97Å; H8-N71 WeakPolarHBondContact CA-OD1 3.37Å; H8-N71 PolarHBondContact ND1-OD1 3.32Å; H8-N71 VanDerWaalsContact ND1-OD1 3.07Å
9A98.9Very high94Very high1 Ų148.5 Ų48.51%0.00826%0.255CS..EExtended strand (participates in β ladder)trans-106.2151.9174.700000112E22 V23 V67 I70 N71A9-E22 CarbonylContact C-O 3.6Å; A9-E22 WeakPolarHBondContact CA-O 3.45Å; A9-V23 HydrophobicContact CB-CG2 4.17Å; A9-V67 HydrophobicContact CB-CG1 4.17Å; A9-V67 WeakPolarHBondContact O-CG1 3.45Å; A9-I70 HydrophobicContact CB-CB 3.68Å; A9-I70 HydrophobicContact CB-CD1 3.53Å; A9-I70 HydrophobicContact CB-CG1 4.23Å; A9-I70 HydrophobicContact CB-CG2 3.67Å; A9-N71 PolarHBondContact N-OD1 3.46Å; A9-N71 PolarHBondContact O-ND2 3.44Å
10R98.9Very high94.2Very high63 Ų6346.1 Ų46.124%0.23824%0.242CC..EExtended strand (participates in β ladder)trans-142166.7173.667-175.167.281.20.8110.9H8 I12 E22 D24H8-R10 PolarHBondContact CD2-NH2 2.97Å; H8-R10 VanDerWaalsContact CD2-NH2 3.35Å; R10-I12 HydrophobicContact CG-CG2 4.11Å; R10-E22 WeakPolarHBondContact CD-OE1 3.42Å; R10-E22 HydrophobicContact CG-CB 4.04Å; R10-E22 IonicContact CZ-OE1 3.74Å; R10-E22 PolarHBondContact N-O 3.03Å; R10-E22 IonicContact NE-OE1 3.58Å; R10-E22 IonicContact NH1-OE1 3.23Å; R10-E22 PolarHBondContact NH1-OE1 3.08Å; R10-E22 PolarHBondContact O-N 3.12Å; R10-D24 IonicContact CZ-OD1 3.59Å; R10-D24 IonicContact CZ-OD2 2.81Å; R10-D24 VanDerWaalsContact CZ-OD2 3.3Å; R10-D24 IonicContact NH1-OD1 3.08Å; R10-D24 PolarHBondContact NH1-OD1 3.25Å; R10-D24 IonicContact NH1-OD2 3.98Å; R10-D24 PolarHBondContact NH1-OD2 3.48Å; R10-D24 IonicContact NH2-OD1 3.66Å; R10-D24 IonicContact NH2-OD2 3.85Å; R10-D24 PolarHBondContact NH2-OD2 2.88Å
11E98.7Very high94.4Very high47 Ų4743.9 Ų43.922%0.2223%0.231CC..EExtended strand (participates in β ladder)trans-93.8128.5171.8-174.9176.8-100.900109.3P19 T20 R57 Y58 V63 V67E11-P19 HydrophobicContact CG-CB 3.69Å; E11-P19 WeakPolarHBondContact OE1-CB 3.34Å; E11-T20 WeakPolarHBondContact CA-O 3.49Å; E11-R57 IonicContact OE1-CZ 2.62Å; E11-R57 IonicContact OE1-NH1 3.27Å; E11-R57 PolarHBondContact OE1-NH1 3.47Å; E11-R57 IonicContact OE1-NH2 3.49Å; E11-R57 IonicContact OE2-CZ 2.69Å; E11-R57 VanDerWaalsContact OE2-CZ 3.27Å; E11-R57 IonicContact OE2-NH1 3.98Å; E11-R57 PolarHBondContact OE2-NH1 2.84Å; E11-R57 VanDerWaalsContact OE2-NH1 3.14Å; E11-R57 IonicContact OE2-NH2 3.71Å; E11-R57 PolarHBondContact OE2-NH2 3.19Å; E11-Y58 WeakPolarHBondContact OE2-CE2 3.46Å; E11-V63 HydrophobicContact CB-CG2 4.12Å; E11-V63 HydrophobicContact CG-CG2 3.59Å; E11-V63 WeakPolarHBondContact OE1-CG2 3.42Å; E11-V63 PolarHBondContact OE1-N 3.25Å; E11-V67 HydrophobicContact CB-CG2 4.49Å
12I98.8Very high96.3Very high25 Ų2537.2 Ų37.213%0.12819%0.189CC..EExtended strand (participates in β ladder)trans-123.7-173.6171.766.8163.4000109.3R10 P19 T20 E22 A35R10-I12 HydrophobicContact CG-CG2 4.11Å; I12-P19 CarbonylContact O-C 3.53Å; I12-P19 VanDerWaalsContact O-CA 3.25Å; I12-P19 WeakPolarHBondContact O-CA 3.38Å; I12-T20 HydrophobicContact CD1-CG2 4.23Å; I12-T20 HydrophobicContact CG1-CG2 3.72Å; I12-T20 PolarHBondContact N-O 3.13Å; I12-T20 PolarHBondContact O-N 3.36Å; I12-E22 HydrophobicContact CD1-CB 3.97Å; I12-E22 HydrophobicContact CG1-CB 4.02Å; I12-E22 HydrophobicContact CG2-CB 3.82Å; I12-A35 HydrophobicContact CD1-CB 3.76Å
13F98.6Very high97.6Very high103 Ų10335.1 Ų35.145%0.45218%0.178SC..EExtended strand (participates in β ladder)trans-112139.7177.1-66.9-84.7000112G17 N18 P19 Y58F13-G17 WeakPolarHBondContact CD1-O 3.37Å; F13-N18 CarbonylContact C-O 3.57Å; F13-N18 WeakPolarHBondContact CA-O 3.07Å; F13-P19 HydrophobicContact CE1-CG 4.46Å; F13-Y58 HydrophobicContact CE1-CD1 4.15Å; F13-Y58 AromaticContact CE1-CE1 3.63Å; F13-Y58 HydrophobicContact CE1-CE1 3.63Å; F13-Y58 AromaticContact CZ-CE1 3.67Å; F13-Y58 HydrophobicContact CZ-CE1 3.67Å; F13-Y58 AromaticContact CZ-CZ 3.81Å
14D98.4Very high98.2Very high9 Ų933.8 Ų33.85%0.04817%0.169CC..  trans-77.6176.9169.279.33.1000111.8R16 G17 N18 T20 G375 E376D14-R16 PolarHBondContact O-N 3.23Å; D14-R16 WeakPolarHBondContact OD1-CA 3.43Å; D14-R16 WeakPolarHBondContact OD1-CB 3.33Å; D14-R16 PolarHBondContact OD1-N 2.71Å; D14-R16 IonicContact OD2-NE 3.55Å; D14-R16 IonicContact OD2-NH2 3.67Å; D14-G17 PolarHBondContact O-N 2.78Å; D14-G17 PolarHBondContact OD1-N 3.48Å; D14-N18 PolarHBondContact N-O 2.84Å; D14-N18 PolarHBondContact OD1-N 2.96Å; D14-T20 HydrophobicContact CB-CG2 4.33Å; D14-G375 WeakPolarHBondContact OD2-CA 3.37Å; D14-E376 CarbonylContact C-O 3.59Å; D14-E376 WeakPolarHBondContact CA-O 3.43Å
15S97.1Very high98.3Very high26 Ų2633.5 Ų33.518%0.18217%0.167CC..THydrogen-bonded Turntrans-63-12.4-178.764.70000114.8S374 E376 R401 E403S15-S374 PolarHBondContact OG-O 3.35Å; S15-E376 WeakPolarHBondContact CB-O 3.48Å; S15-E376 PolarHBondContact N-O 3.09Å; S15-E376 PolarHBondContact OG-N 3.01Å; S15-E376 VanDerWaalsContact OG-N 3.07Å; S15-E376 PolarHBondContact OG-O 3.17Å; S15-R401 PolarHBondContact O-NH2 2.83Å; S15-E403 VanDerWaalsContact CB-CG 3.48Å
16R95.4Very high98.4Very high66 Ų6632.3 Ų32.325%0.24916%0.157CC..THydrogen-bonded Turntrans-104.52.1177.3-59.5178.2-61.1175.6-4.8111.9D14 N18 G39 D210D14-R16 PolarHBondContact O-N 3.23Å; D14-R16 WeakPolarHBondContact OD1-CA 3.43Å; D14-R16 WeakPolarHBondContact OD1-CB 3.33Å; D14-R16 PolarHBondContact OD1-N 2.71Å; D14-R16 IonicContact OD2-NE 3.55Å; D14-R16 IonicContact OD2-NH2 3.67Å; R16-N18 VanDerWaalsContact C-N 3.34Å; R16-G39 PolarHBondContact NH1-O 3.24Å; R16-G39 PolarHBondContact NH2-O 2.94Å; R16-D210 WeakPolarHBondContact CD-OD2 3.36Å
17G97.1Very high98.4Very high45 Ų4527.3 Ų27.346%0.46414%0.136SC..SBendtrans76.317.8-17800000114F13 D14F13-G17 WeakPolarHBondContact CD1-O 3.37Å; D14-G17 PolarHBondContact O-N 2.78Å; D14-G17 PolarHBondContact OD1-N 3.48Å
18N97.9Very high98.3Very high23 Ų2335 Ų3512%0.12317%0.169CC..  trans-89.6149170.6-54.9-69.3000110.1F13 D14 R16 K61F13-N18 CarbonylContact C-O 3.57Å; F13-N18 WeakPolarHBondContact CA-O 3.07Å; D14-N18 PolarHBondContact N-O 2.84Å; D14-N18 PolarHBondContact OD1-N 2.96Å; R16-N18 VanDerWaalsContact C-N 3.34Å; N18-K61 HydrophobicContact CB-CD 4.29Å; N18-K61 WeakPolarHBondContact OD1-CD 3.47Å; N18-K61 PolarHBondContact OD1-NZ 3.29Å
19P98.4Very high98.2Very high1 Ų137.4 Ų37.41%0.00618%0.178CC..EExtended strand (participates in β ladder)trans-58.2146.6173-26.135.5000113.2E11 I12 F13 R51 Y58 V63E11-P19 HydrophobicContact CG-CB 3.69Å; E11-P19 WeakPolarHBondContact OE1-CB 3.34Å; I12-P19 CarbonylContact O-C 3.53Å; I12-P19 VanDerWaalsContact O-CA 3.25Å; I12-P19 WeakPolarHBondContact O-CA 3.38Å; F13-P19 HydrophobicContact CE1-CG 4.46Å; P19-R51 PolarHBondContact O-NH1 3.11Å; P19-Y58 HydrophobicContact CG-CD1 4.01Å; P19-Y58 HydrophobicContact CG-CD2 3.36Å; P19-Y58 HydrophobicContact CG-CE2 3.95Å; P19-Y58 HydrophobicContact CG-CG 3.41Å; P19-Y58 VanDerWaalsContact CG-CG 3.41Å; P19-V63 HydrophobicContact CB-CG2 4.21Å
20T98.8Very high98.1Very high0 Ų039 Ų390%019%0.194CC..EExtended strand (participates in β ladder)trans-149.7168.6168.3-165.80000111.6E11 I12 D14 V36 T377E11-T20 WeakPolarHBondContact CA-O 3.49Å; I12-T20 HydrophobicContact CD1-CG2 4.23Å; I12-T20 HydrophobicContact CG1-CG2 3.72Å; I12-T20 PolarHBondContact N-O 3.13Å; I12-T20 PolarHBondContact O-N 3.36Å; D14-T20 HydrophobicContact CB-CG2 4.33Å; T20-V36 WeakPolarHBondContact CG2-O 3.25Å; T20-V36 PolarHBondContact OG1-O 3.03Å; T20-T377 HydrophobicContact CG2-CG2 3.89Å
21V98.8Very high98.1Very high0 Ų039.4 Ų39.40%020%0.201CC..EExtended strand (participates in β ladder)trans-86.5131.6-175.8177.50000110.8V23 A35 V36 V63 A66 V67 I70 N110V21-V23 HydrophobicContact CG1-CG2 3.97Å; V21-A35 WeakPolarHBondContact O-CA 3.36Å; V21-V36 PolarHBondContact O-N 3.43Å; V21-V63 HydrophobicContact CG2-CB 4.01Å; V21-V63 HydrophobicContact CG2-CG2 4Å; V21-A66 HydrophobicContact CG2-CB 3.89Å; V21-V67 HydrophobicContact CG2-CG2 4.35Å; V21-I70 HydrophobicContact CG1-CD1 3.53Å; V21-N110 HydrophobicContact CG2-CB 4.27Å
22E98.9Very high98.1Very high16 Ų1638.5 Ų38.58%0.07520%0.196CC..EExtended strand (participates in β ladder)trans-120.4140.3164.8-176.7-176.381.700110A9 R10 I12 R33 A34 A35A9-E22 CarbonylContact C-O 3.6Å; A9-E22 WeakPolarHBondContact CA-O 3.45Å; R10-E22 WeakPolarHBondContact CD-OE1 3.42Å; R10-E22 HydrophobicContact CG-CB 4.04Å; R10-E22 IonicContact CZ-OE1 3.74Å; R10-E22 PolarHBondContact N-O 3.03Å; R10-E22 IonicContact NE-OE1 3.58Å; R10-E22 IonicContact NH1-OE1 3.23Å; R10-E22 PolarHBondContact NH1-OE1 3.08Å; R10-E22 PolarHBondContact O-N 3.12Å; I12-E22 HydrophobicContact CD1-CB 3.97Å; I12-E22 HydrophobicContact CG1-CB 4.02Å; I12-E22 HydrophobicContact CG2-CB 3.82Å; E22-R33 VanDerWaalsContact CD-CD 3.47Å; E22-R33 HydrophobicContact CG-CG 3.81Å; E22-R33 IonicContact OE1-NE 2.82Å; E22-R33 VanDerWaalsContact OE2-CD 3.29Å; E22-R33 WeakPolarHBondContact OE2-CD 3.44Å; E22-R33 IonicContact OE2-NE 2.89Å; E22-A34 CarbonylContact C-O 3.55Å; E22-A34 WeakPolarHBondContact CA-O 2.85Å; E22-A35 HydrophobicContact CB-CB 4.38Å; E22-A35 HydrophobicContact CG-CB 4.39Å
23V98.9Very high98.1Very high0 Ų042.6 Ų42.60%021%0.21CC..EExtended strand (participates in β ladder)trans-125.2128.1-178.8-1770000110.6I7 A9 V21 R33 A34 I70 V115 A118I7-V23 HydrophobicContact CG2-CG1 3.68Å; A9-V23 HydrophobicContact CB-CG2 4.17Å; V21-V23 HydrophobicContact CG1-CG2 3.97Å; V23-R33 CarbonylContact O-C 3.57Å; V23-R33 VanDerWaalsContact O-CA 3.29Å; V23-R33 WeakPolarHBondContact O-CA 3.42Å; V23-A34 PolarHBondContact N-O 3.23Å; V23-A34 PolarHBondContact O-N 3.29Å; V23-I70 HydrophobicContact CG2-CD1 3.7Å; V23-V115 HydrophobicContact CG1-CG2 4.12Å; V23-V115 HydrophobicContact CG2-CG2 4.34Å; V23-A118 HydrophobicContact CB-CB 4.46Å; V23-A118 HydrophobicContact CG1-CB 4.22Å
24D98.9Very high98.1Very high1 Ų137.7 Ų37.71%0.00519%0.189CC..EExtended strand (participates in β ladder)trans-100.7124.3165-710.2000109.8I7 H8 R10 Y26 L31 F32 R33I7-D24 CarbonylContact C-O 3.6Å; I7-D24 WeakPolarHBondContact CA-O 3.33Å; H8-D24 PolarHBondContact N-O 3.2Å; H8-D24 PolarHBondContact O-N 2.97Å; R10-D24 IonicContact CZ-OD1 3.59Å; R10-D24 IonicContact CZ-OD2 2.81Å; R10-D24 VanDerWaalsContact CZ-OD2 3.3Å; R10-D24 IonicContact NH1-OD1 3.08Å; R10-D24 PolarHBondContact NH1-OD1 3.25Å; R10-D24 IonicContact NH1-OD2 3.98Å; R10-D24 PolarHBondContact NH1-OD2 3.48Å; R10-D24 IonicContact NH2-OD1 3.66Å; R10-D24 IonicContact NH2-OD2 3.85Å; R10-D24 PolarHBondContact NH2-OD2 2.88Å; D24-Y26 HydrophobicContact CB-CD2 4.5Å; D24-Y26 HydrophobicContact CB-CE2 3.7Å; D24-L31 HydrophobicContact CB-CD1 4.44Å; D24-L31 HydrophobicContact CB-CD2 4.28Å; D24-L31 HydrophobicContact CB-CG 4.2Å; D24-F32 WeakPolarHBondContact CA-O 3.44Å; D24-R33 WeakPolarHBondContact OD1-CG 3.43Å; D24-R33 IonicContact OD1-CZ 3.36Å; D24-R33 IonicContact OD1-NE 2.78Å; D24-R33 PolarHBondContact OD1-NE 3.05Å; D24-R33 IonicContact OD1-NH2 3.41Å; D24-R33 PolarHBondContact OD1-NH2 3.09Å; D24-R33 IonicContact OD2-CZ 2.84Å; D24-R33 IonicContact OD2-NE 2.86Å; D24-R33 IonicContact OD2-NH2 2.63Å; D24-R33 PolarHBondContact OD2-NH2 3.41Å
25L98.8Very high98.2Very high0 Ų037.5 Ų37.50%019%0.189CC..EExtended strand (participates in β ladder)trans-111.1132.6170.6-172.6153.5000109.5I4 I7 T27 L31 F32 V85 A118 V119 A122I4-L25 HydrophobicContact CD1-CD1 4.19Å; I4-L25 HydrophobicContact CG1-CD1 4.22Å; I4-L25 HydrophobicContact CG1-CD2 4.47Å; I4-L25 HydrophobicContact CG2-CD1 4.31Å; I4-L25 HydrophobicContact CG2-CD2 4.43Å; I4-L25 HydrophobicContact CG2-CG 4.12Å; I7-L25 HydrophobicContact CD1-CD1 4.18Å; I7-L25 HydrophobicContact CG1-CB 4.4Å; I7-L25 HydrophobicContact CG1-CD1 4.06Å; I7-L25 HydrophobicContact CG1-CG 3.99Å; L25-T27 HydrophobicContact CD2-CG2 3.55Å; L25-L31 CarbonylContact O-C 3.49Å; L25-L31 WeakPolarHBondContact O-CA 3.41Å; L25-F32 HydrophobicContact CD2-CD2 4.36Å; L25-F32 PolarHBondContact N-O 3.18Å; L25-F32 PolarHBondContact O-N 2.9Å; L25-V85 HydrophobicContact CD2-CG1 4.18Å; L25-A118 HydrophobicContact CB-CB 3.87Å; L25-V119 HydrophobicContact CD1-CB 4.34Å; L25-V119 HydrophobicContact CD1-CG2 3.42Å; L25-V119 VanDerWaalsContact CD1-CG2 3.42Å; L25-A122 HydrophobicContact CD2-CB 3.75Å
26Y98.6Very high98.2Very high66 Ų6636.3 Ų36.326%0.25918%0.18SC..EExtended strand (participates in β ladder)trans-111.2131.3-179-61.1-101.1000110.7L5 K6 D24 G30 L31L5-Y26 WeakPolarHBondContact CB-O 3.48Å; L5-Y26 PolarHBondContact N-O 2.87Å; K6-Y26 HydrophobicContact CB-CD2 3.86Å; K6-Y26 HydrophobicContact CB-CG 4.25Å; K6-Y26 HydrophobicContact CD-CD2 4.14Å; K6-Y26 HydrophobicContact CD-CE2 4.24Å; K6-Y26 HydrophobicContact CG-CD2 4.05Å; K6-Y26 HydrophobicContact CG-CE2 4.47Å; K6-Y26 PolarHBondContact O-N 3.45Å; D24-Y26 HydrophobicContact CB-CD2 4.5Å; D24-Y26 HydrophobicContact CB-CE2 3.7Å; Y26-G30 WeakPolarHBondContact CA-O 3.17Å; Y26-L31 HydrophobicContact CD1-CB 4.12Å; Y26-L31 HydrophobicContact CD1-CG 4.33Å; Y26-L31 HydrophobicContact CE1-CB 3.96Å; Y26-L31 HydrophobicContact CE1-CD1 3.57Å; Y26-L31 HydrophobicContact CE1-CG 3.83Å; Y26-L31 WeakPolarHBondContact OH-CD1 3.38Å
27T98.1Very high98.3Very high7 Ų733.7 Ų33.74%0.04317%0.171CC..EExtended strand (participates in β ladder)trans-127.5-177.9166.3810000109L25 K29 G30 F32 V85 A122L25-T27 HydrophobicContact CD2-CG2 3.55Å; T27-K29 PolarHBondContact O-N 3.37Å; T27-K29 WeakPolarHBondContact OG1-CB 3.38Å; T27-K29 PolarHBondContact OG1-N 2.86Å; T27-G30 PolarHBondContact N-O 3.27Å; T27-G30 PolarHBondContact O-N 2.93Å; T27-G30 VanDerWaalsContact O-N 3.14Å; T27-F32 HydrophobicContact CG2-CD2 4.33Å; T27-F32 HydrophobicContact CG2-CE2 4.09Å; T27-F32 WeakPolarHBondContact OG1-CE2 3.42Å; T27-V85 HydrophobicContact CG2-CG1 3.92Å; T27-V85 HydrophobicContact CG2-CG2 4.43Å; T27-A122 HydrophobicContact CG2-CB 4.1Å
28K96.4Very high98Very high169 Ų16931.7 Ų31.774%0.73515%0.151SC*.THydrogen-bonded Turntrans-68-12.2172.6-50.5175.7175.6176.30112.9M2 L5M2-K28 HydrophobicContact CE-CB 4.32Å; M2-K28 HydrophobicContact SD-CB 3.57Å; M2-K28 VanDerWaalsContact SD-CB 3.57Å; M2-K28 HydrophobicContact SD-CD 4.48Å; M2-K28 HydrophobicContact SD-CG 4.24Å; L5-K28 HydrophobicContact CD1-CG 4.03Å
29K97.3Very high97.1Very high118 Ų11831.1 Ų31.151%0.51315%0.15SC..THydrogen-bonded Turntrans-81.5-14.8172.6-67.2-63.2-166.7175.40113.4M2 T27 F32M2-K29 HydrophobicContact CE-CD 3.78Å; M2-K29 VanDerWaalsContact CE-CE 3.48Å; M2-K29 HydrophobicContact CE-CG 3.81Å; M2-K29 HydrophobicContact SD-CD 4.4Å; M2-K29 HydrophobicContact SD-CG 3.78Å; T27-K29 PolarHBondContact O-N 3.37Å; T27-K29 WeakPolarHBondContact OG1-CB 3.38Å; T27-K29 PolarHBondContact OG1-N 2.86Å; K29-F32 HydrophobicContact CB-CE2 4.17Å; K29-F32 HydrophobicContact CB-CZ 3.77Å
30G97.9Very high95.5Very high33 Ų3333.2 Ų33.234%0.3417%0.167SC..EExtended strand (participates in β ladder)trans131.3-155.1178.900000113.5Y26 T27Y26-G30 WeakPolarHBondContact CA-O 3.17Å; T27-G30 PolarHBondContact N-O 3.27Å; T27-G30 PolarHBondContact O-N 2.93Å; T27-G30 VanDerWaalsContact O-N 3.14Å
31L98.5Very high93.6Very high73 Ų7333.6 Ų33.638%0.38217%0.17SC..EExtended strand (participates in β ladder)trans-101.2130.3-179.7-176.9166.8000109.6D24 L25 Y26 R33D24-L31 HydrophobicContact CB-CD1 4.44Å; D24-L31 HydrophobicContact CB-CD2 4.28Å; D24-L31 HydrophobicContact CB-CG 4.2Å; L25-L31 CarbonylContact O-C 3.49Å; L25-L31 WeakPolarHBondContact O-CA 3.41Å; Y26-L31 HydrophobicContact CD1-CB 4.12Å; Y26-L31 HydrophobicContact CD1-CG 4.33Å; Y26-L31 HydrophobicContact CE1-CB 3.96Å; Y26-L31 HydrophobicContact CE1-CD1 3.57Å; Y26-L31 HydrophobicContact CE1-CG 3.83Å; Y26-L31 WeakPolarHBondContact OH-CD1 3.38Å; L31-R33 HydrophobicContact CD2-CB 3.92Å
32F98.8Very high92.3Very high27 Ų2737.6 Ų37.612%0.11819%0.194CC..EExtended strand (participates in β ladder)trans-119.1121.3176.2-56.3-78000109.3D24 L25 T27 K29 K121 A122 A125D24-F32 WeakPolarHBondContact CA-O 3.44Å; L25-F32 HydrophobicContact CD2-CD2 4.36Å; L25-F32 PolarHBondContact N-O 3.18Å; L25-F32 PolarHBondContact O-N 2.9Å; T27-F32 HydrophobicContact CG2-CD2 4.33Å; T27-F32 HydrophobicContact CG2-CE2 4.09Å; T27-F32 WeakPolarHBondContact OG1-CE2 3.42Å; K29-F32 HydrophobicContact CB-CE2 4.17Å; K29-F32 HydrophobicContact CB-CZ 3.77Å; F32-K121 HydrophobicContact CB-CB 4.12Å; F32-K121 HydrophobicContact CD1-CB 4.29Å; F32-A122 HydrophobicContact CB-CB 4.13Å; F32-A122 HydrophobicContact CD1-CB 4.28Å; F32-A122 HydrophobicContact CD2-CB 3.37Å; F32-A122 HydrophobicContact CE2-CB 3.83Å; F32-A122 HydrophobicContact CG-CB 3.62Å; F32-A122 HydrophobicContact CZ-CB 4.46Å; F32-A125 HydrophobicContact CD1-CB 4.33Å; F32-A125 HydrophobicContact CE1-CB 3.21Å; F32-A125 HydrophobicContact CZ-CB 3.39Å
33R98.9Very high91.1Very high112 Ų11237 Ų3742%0.42319%0.193SC..EExtended strand (participates in β ladder)trans-113.8136.2-172.1179.8171.2-72.1167.64.6111.1E22 V23 D24 L31 K121E22-R33 VanDerWaalsContact CD-CD 3.47Å; E22-R33 HydrophobicContact CG-CG 3.81Å; E22-R33 IonicContact OE1-NE 2.82Å; E22-R33 VanDerWaalsContact OE2-CD 3.29Å; E22-R33 WeakPolarHBondContact OE2-CD 3.44Å; E22-R33 IonicContact OE2-NE 2.89Å; V23-R33 CarbonylContact O-C 3.57Å; V23-R33 VanDerWaalsContact O-CA 3.29Å; V23-R33 WeakPolarHBondContact O-CA 3.42Å; D24-R33 WeakPolarHBondContact OD1-CG 3.43Å; D24-R33 IonicContact OD1-CZ 3.36Å; D24-R33 IonicContact OD1-NE 2.78Å; D24-R33 PolarHBondContact OD1-NE 3.05Å; D24-R33 IonicContact OD1-NH2 3.41Å; D24-R33 PolarHBondContact OD1-NH2 3.09Å; D24-R33 IonicContact OD2-CZ 2.84Å; D24-R33 IonicContact OD2-NE 2.86Å; D24-R33 IonicContact OD2-NH2 2.63Å; D24-R33 PolarHBondContact OD2-NH2 3.41Å; L31-R33 HydrophobicContact CD2-CB 3.92Å; R33-K121 WeakPolarHBondContact O-CD 3.39Å; R33-K121 WeakPolarHBondContact O-CE 3.27Å; R33-K121 PolarHBondContact O-NZ 2.89Å
34A98.8Very high90.4Very high0 Ų042.4 Ų42.40%022%0.221CC..EExtended strand (participates in β ladder)trans-137.6143.2169.100000112.5E22 V23 L117 A118 K121 D379E22-A34 CarbonylContact C-O 3.55Å; E22-A34 WeakPolarHBondContact CA-O 2.85Å; V23-A34 PolarHBondContact N-O 3.23Å; V23-A34 PolarHBondContact O-N 3.29Å; A34-L117 HydrophobicContact CB-CB 3.39Å; A34-L117 HydrophobicContact CB-CD1 4.29Å; A34-L117 HydrophobicContact CB-CG 4.5Å; A34-A118 HydrophobicContact CB-CB 4.13Å; A34-K121 HydrophobicContact CB-CD 4.42Å; A34-D379 WeakPolarHBondContact CA-OD2 3.48Å
35A98.8Very high89.9Confident5 Ų546.8 Ų46.84%0.04124%0.238CC..EExtended strand (participates in β ladder)trans-118.4149.8173.700000111.3I12 V21 E22 T377 D379I12-A35 HydrophobicContact CD1-CB 3.76Å; V21-A35 WeakPolarHBondContact O-CA 3.36Å; E22-A35 HydrophobicContact CB-CB 4.38Å; E22-A35 HydrophobicContact CG-CB 4.39Å; A35-T377 HydrophobicContact CB-CG2 3.92Å; A35-D379 HydrophobicContact CB-CB 4.32Å; A35-D379 PolarHBondContact N-OD2 3.14Å
36V98.6Very high89.5Confident1 Ų148 Ų481%0.00624%0.243CC..  trans-103.2131.2-174.1176.80000110.8T20 V21 N110 L113 G114 N346T20-V36 WeakPolarHBondContact CG2-O 3.25Å; T20-V36 PolarHBondContact OG1-O 3.03Å; V21-V36 PolarHBondContact O-N 3.43Å; V36-N110 HydrophobicContact CG1-CB 3.95Å; V36-N110 WeakPolarHBondContact CG2-O 3.33Å; V36-L113 HydrophobicContact CG1-CD2 3.9Å; V36-L113 HydrophobicContact CG2-CB 4.29Å; V36-L113 HydrophobicContact CG2-CD2 4.34Å; V36-L113 HydrophobicContact CG2-CG 4.38Å; V36-G114 VanDerWaalsContact CG2-CA 3.47Å; V36-N346 HydrophobicContact CG1-CB 4.5Å
37P97.3Very high89.2Confident10 Ų1045.5 Ų45.57%0.06524%0.236CC..  trans-80.2164.1174.934.9-36.9000112N346 R373 G375P37-N346 HydrophobicContact CG-CB 4.35Å; P37-N346 PolarHBondContact O-ND2 2.64Å; P37-R373 HydrophobicContact CB-CB 4.09Å; P37-R373 HydrophobicContact CB-CG 3.98Å; P37-R373 HydrophobicContact CG-CG 4.08Å; P37-G375 CarbonylContact C-O 3.56Å; P37-G375 VanDerWaalsContact CA-O 3.31Å; P37-G375 WeakPolarHBondContact CA-O 3.35Å; P37-G375 WeakPolarHBondContact CB-O 3.46Å
38S90.7Very high88.9Confident4 Ų448.6 Ų48.63%0.02825%0.252CS..BIsolated β-bridgetrans-130.2145.9177.3-175.80000112E49 R51 R373 G375S38-E49 PolarHBondContact OG-OE2 3.38Å; S38-R51 PolarHBondContact OG-NH2 2.93Å; S38-R373 WeakPolarHBondContact O-CB 3.48Å; S38-G375 PolarHBondContact N-O 3.04Å; S38-G375 CarbonylContact O-C 3.59Å; S38-G375 WeakPolarHBondContact O-CA 3.17Å; S38-G375 PolarHBondContact O-N 2.99Å
39G78.3Confident88.8Confident10 Ų1043 Ų4310%0.10323%0.229CC..  trans-84.7171.5179.600000115.3R16R16-G39 PolarHBondContact NH1-O 3.24Å; R16-G39 PolarHBondContact NH2-O 2.94Å
40A65.3Low88.8Confident46 Ų4638.7 Ų38.738%0.3821%0.211SC..SBendtrans-114-59.4168.100000109.3S374A40-S374 WeakPolarHBondContact CB-OG 3.14Å; A40-S374 PolarHBondContact N-OG 2.89Å
41S59.7Low88.8Confident8 Ų838.7 Ų38.76%0.05620%0.201CC..SBendtrans-79.3127159.153.70000108.5R373S41-R373 PolarHBondContact O-NH2 3.1Å
42T71.8Confident88.7Confident83 Ų8335.7 Ų35.751%0.50919%0.185SC..  trans-129.4115.7177.5550000107.9E46T42-E46 WeakPolarHBondContact CA-OE1 3.46Å
43G72.3Confident88.6Confident5 Ų540.4 Ų40.45%0.05221%0.212CC..  trans-57.1146.417100000111Y45 E46 D320G43-Y45 PolarHBondContact O-N 2.94Å; G43-E46 PolarHBondContact N-OE1 3.17Å; G43-E46 WeakPolarHBondContact O-CG 3.49Å; G43-E46 PolarHBondContact O-N 3.05Å; G43-D320 WeakPolarHBondContact CA-OD1 3.46Å; G43-D320 PolarHBondContact N-OD1 2.97Å; G43-D320 VanDerWaalsContact N-OD1 3.16Å
44I84.6Confident88.5Confident112 Ų11238.4 Ų38.457%0.57421%0.21SC*.THydrogen-bonded Turntrans-70.2-8.4-171.563.5173.1000113.6Q299I44-Q299 VanDerWaalsContact N-OE1 3.13Å
45Y89.3Confident88.4Confident94 Ų9447.5 Ų47.537%0.36925%0.249SC..THydrogen-bonded Turntrans-107.33.7-176.6-60.1-72.2000113.7G43 D300 R328G43-Y45 PolarHBondContact O-N 2.94Å; Y45-D300 PolarHBondContact OH-OD1 2.77Å; Y45-D300 PolarHBondContact OH-OD2 3.35Å; Y45-R328 VanDerWaalsContact CD2-CZ 3.5Å; Y45-R328 VanDerWaalsContact CE2-CZ 3.47Å
46E89.6Confident88.3Confident25 Ų2553.4 Ų53.412%0.11729%0.285CS..SBendtrans-61.9154177.1-69.4-171.7-164.900111.9T42 G43 V323 Q347 R373T42-E46 WeakPolarHBondContact CA-OE1 3.46Å; G43-E46 PolarHBondContact N-OE1 3.17Å; G43-E46 WeakPolarHBondContact O-CG 3.49Å; G43-E46 PolarHBondContact O-N 3.05Å; E46-V323 HydrophobicContact CG-CB 3.91Å; E46-V323 HydrophobicContact CG-CG1 3.68Å; E46-Q347 VanDerWaalsContact CD-CG 3.45Å; E46-Q347 HydrophobicContact CG-CB 4.08Å; E46-Q347 HydrophobicContact CG-CG 3.77Å; E46-Q347 PolarHBondContact OE1-NE2 3.21Å; E46-R373 IonicContact OE1-CZ 3.79Å; E46-R373 IonicContact OE1-NH1 3.3Å; E46-R373 IonicContact OE1-NH2 3.91Å; E46-R373 PolarHBondContact OE1-NH2 2.87Å; E46-R373 IonicContact OE2-CZ 3.59Å; E46-R373 IonicContact OE2-NH1 3.96Å; E46-R373 PolarHBondContact OE2-NH1 3.28Å; E46-R373 IonicContact OE2-NH2 2.93Å; E46-R373 PolarHBondContact OE2-NH2 3.06Å
47A92.4Very high88.3Confident13 Ų1357.3 Ų57.311%0.10730%0.299CS..PPolyproline II helixtrans-59.9141.5161.600000110E49 K104 A109 Q347A47-E49 PolarHBondContact O-N 3.44Å; A47-K104 HydrophobicContact CB-CD 4.07Å; A47-A109 HydrophobicContact CB-CB 3.62Å; A47-Q347 WeakPolarHBondContact CB-O 3.25Å; A47-Q347 PolarHBondContact N-O 2.95Å
48L92.5Very high88.2Confident72 Ų7261.4 Ų61.438%0.37731%0.314SS..PPolyproline II helixtrans-81.8118.9-165.8-174.1135000111.8L50 N103 G108 A109L48-L50 PolarHBondContact O-N 2.82Å; L48-N103 PolarHBondContact N-O 3.46Å; L48-G108 CarbonylContact O-C 3.56Å; L48-G108 WeakPolarHBondContact O-CA 3.35Å; L48-A109 WeakPolarHBondContact O-CB 3.47Å; L48-A109 PolarHBondContact O-N 2.93Å
49E94.3Very high88.5Confident51 Ų5169 Ų6924%0.23835%0.351CS..PPolyproline II helixtrans-69.1120.6165.3-175.4178.1-173.900110S38 A47 R51 N110S38-E49 PolarHBondContact OG-OE2 3.38Å; A47-E49 PolarHBondContact O-N 3.44Å; E49-R51 VanDerWaalsContact CD-NE 3.28Å; E49-R51 VanDerWaalsContact CD-NH2 3.29Å; E49-R51 PolarHBondContact O-N 2.64Å; E49-R51 IonicContact OE1-CZ 3.4Å; E49-R51 IonicContact OE1-NE 3.59Å; E49-R51 PolarHBondContact OE1-NE 3.5Å; E49-R51 IonicContact OE1-NH1 3.35Å; E49-R51 IonicContact OE1-NH2 2.82Å; E49-R51 PolarHBondContact OE1-NH2 3.33Å; E49-R51 IonicContact OE2-CZ 2.79Å; E49-R51 IonicContact OE2-NE 2.77Å; E49-R51 IonicContact OE2-NH2 3.8Å; E49-R51 PolarHBondContact OE2-NH2 3.08Å; E49-N110 HydrophobicContact CG-CB 4.08Å; E49-N110 WeakPolarHBondContact CG-ND2 3.27Å
50L96.6Very high89.4Confident28 Ų2868.9 Ų68.915%0.14735%0.35CS..  trans-83.5115.5178.8-176.865.3000110.7L48 K65 A66 F107 N110L48-L50 PolarHBondContact O-N 2.82Å; L50-K65 HydrophobicContact CD2-CB 3.99Å; L50-K65 HydrophobicContact CG-CB 4.38Å; L50-A66 HydrophobicContact CB-CB 4.41Å; L50-A66 HydrophobicContact CD2-CB 4.49Å; L50-F107 WeakPolarHBondContact CD2-O 3.41Å; L50-N110 PolarHBondContact N-OD1 3.35Å; L50-N110 PolarHBondContact O-ND2 3.3Å
51R97.2Very high90.9Very high33 Ų3370.9 Ų70.913%0.12535%0.35CS..  trans-110.1153.4174-62.7-67.8-172.9166.4-8.5111.3P19 S38 E49 N53 K61 G62P19-R51 PolarHBondContact O-NH1 3.11Å; S38-R51 PolarHBondContact OG-NH2 2.93Å; E49-R51 VanDerWaalsContact CD-NE 3.28Å; E49-R51 VanDerWaalsContact CD-NH2 3.29Å; E49-R51 PolarHBondContact O-N 2.64Å; E49-R51 IonicContact OE1-CZ 3.4Å; E49-R51 IonicContact OE1-NE 3.59Å; E49-R51 PolarHBondContact OE1-NE 3.5Å; E49-R51 IonicContact OE1-NH1 3.35Å; E49-R51 IonicContact OE1-NH2 2.82Å; E49-R51 PolarHBondContact OE1-NH2 3.33Å; E49-R51 IonicContact OE2-CZ 2.79Å; E49-R51 IonicContact OE2-NE 2.77Å; E49-R51 IonicContact OE2-NH2 3.8Å; E49-R51 PolarHBondContact OE2-NH2 3.08Å; R51-N53 VanDerWaalsContact C-N 3.33Å; R51-N53 PolarHBondContact O-N 3.42Å; R51-N53 PolarHBondContact O-ND2 3.11Å; R51-K61 PolarHBondContact NH1-O 2.75Å; R51-G62 CarbonylContact C-O 3.57Å; R51-G62 WeakPolarHBondContact CA-O 3.15Å
52D97.2Very high92.8Very high11 Ų1170.5 Ų70.56%0.05935%0.348CS..  trans-67.9-34.4-177.7-68.3-17.5000112.3D54 R57 G62 V63 S64 K65D52-D54 PolarHBondContact O-N 3.47Å; D52-R57 IonicContact OD2-NH1 3.14Å; D52-G62 WeakPolarHBondContact CB-O 3.12Å; D52-G62 VanDerWaalsContact CG-O 3.25Å; D52-G62 PolarHBondContact N-O 3.05Å; D52-G62 VanDerWaalsContact OD2-CA 3.27Å; D52-G62 WeakPolarHBondContact OD2-CA 3.28Å; D52-V63 PolarHBondContact OD2-N 3.24Å; D52-S64 PolarHBondContact OD1-N 3.29Å; D52-S64 PolarHBondContact OD1-OG 2.89Å; D52-S64 VanDerWaalsContact OD1-OG 3.11Å; D52-S64 WeakPolarHBondContact OD2-CB 3.22Å; D52-S64 PolarHBondContact OD2-N 3.47Å; D52-S64 PolarHBondContact OD2-OG 3.15Å; D52-K65 PolarHBondContact O-NZ 3.35Å; D52-K65 WeakPolarHBondContact OD1-CG 3.25Å; D52-K65 PolarHBondContact OD1-N 3.24Å
53N96.3Very high94.1Very high126 Ų12666.6 Ų66.667%0.67432%0.324SS*.  trans59.120.4-174.1-65-52000114.5R51 K55 G60R51-N53 VanDerWaalsContact C-N 3.33Å; R51-N53 PolarHBondContact O-N 3.42Å; R51-N53 PolarHBondContact O-ND2 3.11Å; N53-K55 PolarHBondContact O-N 3.05Å; N53-G60 VanDerWaalsContact CA-O 3.28Å; N53-G60 WeakPolarHBondContact CA-O 3.45Å; N53-G60 PolarHBondContact N-O 3.34Å
54D96.9Very high95.3Very high70 Ų7068.9 Ų68.937%0.37434%0.339SS..  trans-82103170.6178.80.4000110.6D52 T56 R57 G60D52-D54 PolarHBondContact O-N 3.47Å; D54-T56 VanDerWaalsContact CG-OG1 3.27Å; D54-T56 PolarHBondContact O-N 3.33Å; D54-T56 WeakPolarHBondContact OD1-CB 3.3Å; D54-T56 PolarHBondContact OD1-N 3.4Å; D54-T56 PolarHBondContact OD1-OG1 3.33Å; D54-T56 PolarHBondContact OD2-OG1 2.89Å; D54-R57 HydrophobicContact CB-CB 4.45Å; D54-R57 PolarHBondContact O-N 2.99Å; D54-G60 WeakPolarHBondContact O-CA 3.22Å; D54-G60 PolarHBondContact O-N 2.72Å; D54-G60 VanDerWaalsContact O-N 3.09Å
55K96.1Very high96Very high190 Ų19068.1 Ų68.183%0.82633%0.331SS*.THydrogen-bonded Turntrans-59.3-20.3-178.9-66.3-173.8178.8-178.40113.6N53 R57N53-K55 PolarHBondContact O-N 3.05Å; K55-R57 VanDerWaalsContact C-N 3.31Å
56T97.5Very high96.4Very high130 Ų13063.6 Ų63.680%0.79831%0.314SS*.THydrogen-bonded Turntrans-80.3-14.1178.773.10000112.9D54D54-T56 VanDerWaalsContact CG-OG1 3.27Å; D54-T56 PolarHBondContact O-N 3.33Å; D54-T56 WeakPolarHBondContact OD1-CB 3.3Å; D54-T56 PolarHBondContact OD1-N 3.4Å; D54-T56 PolarHBondContact OD1-OG1 3.33Å; D54-T56 PolarHBondContact OD2-OG1 2.89Å
57R97.6Very high96.9Very high82 Ų8263.3 Ų63.331%0.30931%0.314SS..SBendtrans-125.3118.6-176.7-170.1-177-175.7-93.8-3.8111.2E11 D52 D54 K55 M59 G60E11-R57 IonicContact OE1-CZ 2.62Å; E11-R57 IonicContact OE1-NH1 3.27Å; E11-R57 PolarHBondContact OE1-NH1 3.47Å; E11-R57 IonicContact OE1-NH2 3.49Å; E11-R57 IonicContact OE2-CZ 2.69Å; E11-R57 VanDerWaalsContact OE2-CZ 3.27Å; E11-R57 IonicContact OE2-NH1 3.98Å; E11-R57 PolarHBondContact OE2-NH1 2.84Å; E11-R57 VanDerWaalsContact OE2-NH1 3.14Å; E11-R57 IonicContact OE2-NH2 3.71Å; E11-R57 PolarHBondContact OE2-NH2 3.19Å; D52-R57 IonicContact OD2-NH1 3.14Å; D54-R57 HydrophobicContact CB-CB 4.45Å; D54-R57 PolarHBondContact O-N 2.99Å; K55-R57 VanDerWaalsContact C-N 3.31Å; R57-M59 PolarHBondContact O-N 3.31Å; R57-M59 VanDerWaalsContact O-N 3.08Å; R57-G60 PolarHBondContact O-N 2.78Å
58Y97.1Very high97.2Very high96 Ų9667 Ų6738%0.37633%0.329SS..G310 helixtrans48.437.9179.2-57.1-64.1000113.7E11 F13 P19 G60 K61E11-Y58 WeakPolarHBondContact OE2-CE2 3.46Å; F13-Y58 HydrophobicContact CE1-CD1 4.15Å; F13-Y58 AromaticContact CE1-CE1 3.63Å; F13-Y58 HydrophobicContact CE1-CE1 3.63Å; F13-Y58 AromaticContact CZ-CE1 3.67Å; F13-Y58 HydrophobicContact CZ-CE1 3.67Å; F13-Y58 AromaticContact CZ-CZ 3.81Å; P19-Y58 HydrophobicContact CG-CD1 4.01Å; P19-Y58 HydrophobicContact CG-CD2 3.36Å; P19-Y58 HydrophobicContact CG-CE2 3.95Å; P19-Y58 HydrophobicContact CG-CG 3.41Å; P19-Y58 VanDerWaalsContact CG-CG 3.41Å; Y58-G60 PolarHBondContact O-N 2.89Å; Y58-K61 WeakPolarHBondContact O-CB 3.3Å; Y58-K61 PolarHBondContact O-N 2.93Å
59M96.6Very high97.5Very high163 Ų16366 Ų6680%0.80332%0.322SS*.G310 helixtrans57.331.3-179.7-44.8-56.3146.300113.8R57R57-M59 PolarHBondContact O-N 3.31Å; R57-M59 VanDerWaalsContact O-N 3.08Å
60G96.8Very high97.7Very high8 Ų863.6 Ų63.68%0.08231%0.311CS..G310 helixtrans89.3-5.4-176.400000114.9N53 D54 R57 Y58N53-G60 VanDerWaalsContact CA-O 3.28Å; N53-G60 WeakPolarHBondContact CA-O 3.45Å; N53-G60 PolarHBondContact N-O 3.34Å; D54-G60 WeakPolarHBondContact O-CA 3.22Å; D54-G60 PolarHBondContact O-N 2.72Å; D54-G60 VanDerWaalsContact O-N 3.09Å; R57-G60 PolarHBondContact O-N 2.78Å; Y58-G60 PolarHBondContact O-N 2.89Å
61K97.6Very high97.8Very high89 Ų8964.5 Ų64.539%0.38732%0.316SS..THydrogen-bonded Turntrans-94.412.5-171.1-55.9179.9-177.3-178.20114.4N18 R51 Y58N18-K61 HydrophobicContact CB-CD 4.29Å; N18-K61 WeakPolarHBondContact OD1-CD 3.47Å; N18-K61 PolarHBondContact OD1-NZ 3.29Å; R51-K61 PolarHBondContact NH1-O 2.75Å; Y58-K61 WeakPolarHBondContact O-CB 3.3Å; Y58-K61 PolarHBondContact O-N 2.93Å
62G98.3Very high97.9Very high0 Ų069.8 Ų69.80%034%0.339CS..  trans-56.9155.917200000112.4R51 D52R51-G62 CarbonylContact C-O 3.57Å; R51-G62 WeakPolarHBondContact CA-O 3.15Å; D52-G62 WeakPolarHBondContact CB-O 3.12Å; D52-G62 VanDerWaalsContact CG-O 3.25Å; D52-G62 PolarHBondContact N-O 3.05Å; D52-G62 VanDerWaalsContact OD2-CA 3.27Å; D52-G62 WeakPolarHBondContact OD2-CA 3.28Å
63V98.6Very high97.9Very high0 Ų072 Ų720%035%0.353CS..  trans-124.123.8176.2-64.60000112.2E11 P19 V21 D52 K65 A66 V67E11-V63 HydrophobicContact CB-CG2 4.12Å; E11-V63 HydrophobicContact CG-CG2 3.59Å; E11-V63 WeakPolarHBondContact OE1-CG2 3.42Å; E11-V63 PolarHBondContact OE1-N 3.25Å; P19-V63 HydrophobicContact CB-CG2 4.21Å; V21-V63 HydrophobicContact CG2-CB 4.01Å; V21-V63 HydrophobicContact CG2-CG2 4Å; D52-V63 PolarHBondContact OD2-N 3.24Å; V63-K65 VanDerWaalsContact C-N 3.26Å; V63-K65 PolarHBondContact O-N 3.42Å; V63-A66 HydrophobicContact CB-CB 4.46Å; V63-A66 PolarHBondContact O-N 2.9Å; V63-V67 HydrophobicContact CG2-CG2 4.36Å; V63-V67 WeakPolarHBondContact O-CG2 3.47Å; V63-V67 PolarHBondContact O-N 3.49Å
64S98.5Very high98Very high54 Ų5466 Ų6638%0.37832%0.321SS..Hα-helixtrans-60.5-34.4-177.864.30000112.7D52 V67 E68D52-S64 PolarHBondContact OD1-N 3.29Å; D52-S64 PolarHBondContact OD1-OG 2.89Å; D52-S64 VanDerWaalsContact OD1-OG 3.11Å; D52-S64 WeakPolarHBondContact OD2-CB 3.22Å; D52-S64 PolarHBondContact OD2-N 3.47Å; D52-S64 PolarHBondContact OD2-OG 3.15Å; S64-V67 PolarHBondContact O-N 3.34Å; S64-E68 WeakPolarHBondContact O-CB 3.07Å; S64-E68 PolarHBondContact O-N 2.76Å
65K98.6Very high98.1Very high95 Ų9563 Ų6341%0.41331%0.306SS..Hα-helixtrans-63.5-45.7174.3-68.9175.6-176.6166.20112.5L50 D52 V63 E68 H69L50-K65 HydrophobicContact CD2-CB 3.99Å; L50-K65 HydrophobicContact CG-CB 4.38Å; D52-K65 PolarHBondContact O-NZ 3.35Å; D52-K65 WeakPolarHBondContact OD1-CG 3.25Å; D52-K65 PolarHBondContact OD1-N 3.24Å; V63-K65 VanDerWaalsContact C-N 3.26Å; V63-K65 PolarHBondContact O-N 3.42Å; K65-E68 WeakPolarHBondContact O-CB 3.46Å; K65-E68 PolarHBondContact O-N 2.89Å; K65-H69 PolarHBondContact O-CD2 2.99Å; K65-H69 PolarHBondContact O-N 3.46Å
66A98.6Very high98.2Very high0 Ų057.2 Ų57.20%029%0.288CS..Hα-helixtrans-63.6-43.7177.300000111.2V21 L50 V63 E68 H69 I70 A111V21-A66 HydrophobicContact CG2-CB 3.89Å; L50-A66 HydrophobicContact CB-CB 4.41Å; L50-A66 HydrophobicContact CD2-CB 4.49Å; V63-A66 HydrophobicContact CB-CB 4.46Å; V63-A66 PolarHBondContact O-N 2.9Å; A66-E68 VanDerWaalsContact C-N 3.3Å; A66-E68 PolarHBondContact O-N 2.89Å; A66-H69 PolarHBondContact O-N 3.3Å; A66-I70 WeakPolarHBondContact O-CG1 3.48Å; A66-I70 PolarHBondContact O-N 3.16Å; A66-I70 VanDerWaalsContact O-N 3.1Å; A66-A111 HydrophobicContact CB-CB 4.26Å
67V98.9Very high98.2Very high19 Ų1952.2 Ų52.212%0.11526%0.26CS..Hα-helixtrans-59.9-40.6174.1169.60000111.4A9 E11 V21 V63 S64 I70 N71A9-V67 HydrophobicContact CB-CG1 4.17Å; A9-V67 WeakPolarHBondContact O-CG1 3.45Å; E11-V67 HydrophobicContact CB-CG2 4.49Å; V21-V67 HydrophobicContact CG2-CG2 4.35Å; V63-V67 HydrophobicContact CG2-CG2 4.36Å; V63-V67 WeakPolarHBondContact O-CG2 3.47Å; V63-V67 PolarHBondContact O-N 3.49Å; S64-V67 PolarHBondContact O-N 3.34Å; V67-I70 PolarHBondContact O-N 3.46Å; V67-N71 VanDerWaalsContact CG1-ND2 3.34Å; V67-N71 WeakPolarHBondContact CG1-ND2 3.16Å; V67-N71 WeakPolarHBondContact O-CB 3.44Å; V67-N71 PolarHBondContact O-N 2.91Å; V67-N71 PolarHBondContact O-ND2 2.9Å; V67-N71 VanDerWaalsContact O-ND2 3.09Å
68E98.8Very high98.2Very high90 Ų9048.5 Ų48.542%0.42125%0.246SC..Hα-helixtrans-65.3-44.4176.4-175.4172.4-171.500112S64 K65 A66 I70 N71 K72S64-E68 WeakPolarHBondContact O-CB 3.07Å; S64-E68 PolarHBondContact O-N 2.76Å; K65-E68 WeakPolarHBondContact O-CB 3.46Å; K65-E68 PolarHBondContact O-N 2.89Å; A66-E68 VanDerWaalsContact C-N 3.3Å; A66-E68 PolarHBondContact O-N 2.89Å; E68-I70 VanDerWaalsContact C-N 3.29Å; E68-I70 PolarHBondContact O-N 3.21Å; E68-N71 PolarHBondContact O-N 2.95Å; E68-K72 HydrophobicContact CG-CD 3.65Å; E68-K72 HydrophobicContact CG-CG 4.05Å; E68-K72 WeakPolarHBondContact O-CB 3.27Å; E68-K72 PolarHBondContact O-N 2.93Å; E68-K72 WeakPolarHBondContact OE1-CD 3.42Å; E68-K72 WeakPolarHBondContact OE1-CE 3.46Å; E68-K72 IonicContact OE1-NZ 3.3Å; E68-K72 PolarHBondContact OE1-NZ 3.28Å
69H98.8Very high98.1Very high52 Ų5246.4 Ų46.424%0.24124%0.244CC..Hα-helixtrans-57.4-41.8174.8-73.3-50.7000112.2K65 A66 T73 I74 K106 F107K65-H69 PolarHBondContact O-CD2 2.99Å; K65-H69 PolarHBondContact O-N 3.46Å; A66-H69 PolarHBondContact O-N 3.3Å; H69-T73 WeakPolarHBondContact O-CA 3.44Å; H69-T73 VanDerWaalsContact O-CB 3.27Å; H69-T73 WeakPolarHBondContact O-CB 3.39Å; H69-T73 PolarHBondContact O-N 2.91Å; H69-I74 PolarHBondContact O-N 3.14Å; H69-K106 PolarHBondContact NE2-O 3.1Å; H69-F107 HydrophobicContact CB-CB 4.4Å; H69-F107 HydrophobicContact CB-CD1 4.11Å; H69-F107 AromaticContact CG-CD1 3.91Å; H69-F107 AromaticContact ND1-CD1 3.86Å
70I98.9Very high98.1Very high0 Ų043 Ų430%024%0.236CC..Iπ-helixtrans-63.5-55.1175.5-62.1163.3000110.2I7 A9 V21 V23 A66 V67 E68 K72 I74 A75 A111 V115I7-I70 HydrophobicContact CG2-CG2 3.75Å; A9-I70 HydrophobicContact CB-CB 3.68Å; A9-I70 HydrophobicContact CB-CD1 3.53Å; A9-I70 HydrophobicContact CB-CG1 4.23Å; A9-I70 HydrophobicContact CB-CG2 3.67Å; V21-I70 HydrophobicContact CG1-CD1 3.53Å; V23-I70 HydrophobicContact CG2-CD1 3.7Å; A66-I70 WeakPolarHBondContact O-CG1 3.48Å; A66-I70 PolarHBondContact O-N 3.16Å; A66-I70 VanDerWaalsContact O-N 3.1Å; V67-I70 PolarHBondContact O-N 3.46Å; E68-I70 VanDerWaalsContact C-N 3.29Å; E68-I70 PolarHBondContact O-N 3.21Å; I70-K72 PolarHBondContact O-N 3.12Å; I70-I74 HydrophobicContact CG1-CD1 4.22Å; I70-I74 PolarHBondContact O-N 3.05Å; I70-A75 WeakPolarHBondContact O-CB 3.4Å; I70-A75 PolarHBondContact O-N 3.25Å; I70-A111 HydrophobicContact CD1-CB 4.13Å; I70-A111 HydrophobicContact CG1-CB 3.82Å; I70-V115 HydrophobicContact CD1-CG2 4.45Å; I70-V115 HydrophobicContact CG1-CG2 4.16Å; I70-V115 HydrophobicContact CG2-CG2 3.78Å
71N98.9Very high97.9Very high47 Ų4748.9 Ų48.925%0.25126%0.259SS..Iπ-helixtrans-67.7-36.9-171.3-76.2-45000113.5H8 A9 V67 E68H8-N71 WeakPolarHBondContact CA-OD1 3.37Å; H8-N71 PolarHBondContact ND1-OD1 3.32Å; H8-N71 VanDerWaalsContact ND1-OD1 3.07Å; A9-N71 PolarHBondContact N-OD1 3.46Å; A9-N71 PolarHBondContact O-ND2 3.44Å; V67-N71 VanDerWaalsContact CG1-ND2 3.34Å; V67-N71 WeakPolarHBondContact CG1-ND2 3.16Å; V67-N71 WeakPolarHBondContact O-CB 3.44Å; V67-N71 PolarHBondContact O-N 2.91Å; V67-N71 PolarHBondContact O-ND2 2.9Å; V67-N71 VanDerWaalsContact O-ND2 3.09Å; E68-N71 PolarHBondContact O-N 2.95Å
72K98.7Very high97.5Very high143 Ų14350 Ų5062%0.62227%0.269SS*.Iπ-helixtrans-100.4-20.4-172.8-62.1-169.2-175.1172.20114.3E68 I70E68-K72 HydrophobicContact CG-CD 3.65Å; E68-K72 HydrophobicContact CG-CG 4.05Å; E68-K72 WeakPolarHBondContact O-CB 3.27Å; E68-K72 PolarHBondContact O-N 2.93Å; E68-K72 WeakPolarHBondContact OE1-CD 3.42Å; E68-K72 WeakPolarHBondContact OE1-CE 3.46Å; E68-K72 IonicContact OE1-NZ 3.3Å; E68-K72 PolarHBondContact OE1-NZ 3.28Å; I70-K72 PolarHBondContact O-N 3.12Å
73T98.6Very high97.1Very high57 Ų5750.3 Ų50.335%0.3527%0.271SS..Iπ-helixtrans-122-58.7-174.2-50.80000112.4H69 A77 M98 F107H69-T73 WeakPolarHBondContact O-CA 3.44Å; H69-T73 VanDerWaalsContact O-CB 3.27Å; H69-T73 WeakPolarHBondContact O-CB 3.39Å; H69-T73 PolarHBondContact O-N 2.91Å; T73-A77 VanDerWaalsContact O-CB 3.31Å; T73-A77 WeakPolarHBondContact O-CB 3.26Å; T73-A77 PolarHBondContact O-N 3.28Å; T73-M98 HydrophobicContact CG2-CE 4.03Å; T73-F107 HydrophobicContact CG2-CE1 3.99Å; T73-F107 HydrophobicContact CG2-CZ 3.88Å
74I98.6Very high97Very high0 Ų050.6 Ų50.60%027%0.273CS..Iπ-helixtrans-69.2-47-174.7-58.8172.9000110.6H69 I70 A77 L78 M95 F107 A111 V115H69-I74 PolarHBondContact O-N 3.14Å; I70-I74 HydrophobicContact CG1-CD1 4.22Å; I70-I74 PolarHBondContact O-N 3.05Å; I74-A77 PolarHBondContact O-N 3.44Å; I74-L78 HydrophobicContact CG2-CD1 3.72Å; I74-L78 HydrophobicContact CG2-CG 4.06Å; I74-L78 WeakPolarHBondContact O-CG 3.47Å; I74-L78 PolarHBondContact O-N 2.78Å; I74-M95 HydrophobicContact CG2-CG 4.03Å; I74-M95 HydrophobicContact CG2-SD 3.87Å; I74-F107 HydrophobicContact CD1-CB 4.45Å; I74-F107 HydrophobicContact CD1-CD2 4Å; I74-F107 HydrophobicContact CD1-CG 4.32Å; I74-F107 HydrophobicContact CG1-CD2 4.16Å; I74-F107 HydrophobicContact CG1-CE2 4.21Å; I74-A111 HydrophobicContact CD1-CB 4.35Å; I74-V115 HydrophobicContact CG2-CG1 4.38Å; I74-V115 HydrophobicContact CG2-CG2 4.18Å
75A98.4Very high96.9Very high7 Ų748 Ų486%0.05826%0.255CS..Hα-helixtrans-60.5-52.1-176.400000113I7 I70 A77 V79I7-A75 HydrophobicContact CB-CB 3.64Å; I7-A75 HydrophobicContact CG2-CB 4.07Å; I70-A75 WeakPolarHBondContact O-CB 3.4Å; I70-A75 PolarHBondContact O-N 3.25Å; A75-A77 VanDerWaalsContact C-N 3.3Å; A75-A77 PolarHBondContact O-N 2.85Å; A75-V79 WeakPolarHBondContact O-CB 3.46Å; A75-V79 VanDerWaalsContact O-CG2 3.25Å; A75-V79 WeakPolarHBondContact O-CG2 3.46Å; A75-V79 PolarHBondContact O-N 3.09Å; A75-V79 VanDerWaalsContact O-N 3.09Å
76P97.9Very high96.9Very high70 Ų7045.4 Ų45.446%0.45525%0.247SC..Hα-helixtrans-61.6-38.6176.9-23.235000112.6S80P76-S80 VanDerWaalsContact O-CB 3.3Å; P76-S80 WeakPolarHBondContact O-CB 3.41Å; P76-S80 PolarHBondContact O-N 3.37Å; P76-S80 PolarHBondContact O-OG 2.96Å
77A97.4Very high96.8Very high24 Ų2448.9 Ų48.920%0.19826%0.263CS..Hα-helixtrans-63.8-52.3-18000000111.6T73 I74 A75 V79 S80 K81 M98T73-A77 VanDerWaalsContact O-CB 3.31Å; T73-A77 WeakPolarHBondContact O-CB 3.26Å; T73-A77 PolarHBondContact O-N 3.28Å; I74-A77 PolarHBondContact O-N 3.44Å; A75-A77 VanDerWaalsContact C-N 3.3Å; A75-A77 PolarHBondContact O-N 2.85Å; A77-V79 PolarHBondContact O-N 3.49Å; A77-S80 PolarHBondContact O-N 3.28Å; A77-S80 PolarHBondContact O-OG 3.02Å; A77-K81 VanDerWaalsContact O-CG 3.28Å; A77-K81 WeakPolarHBondContact O-CG 3.29Å; A77-K81 PolarHBondContact O-N 3.21Å; A77-M98 HydrophobicContact CB-CE 3.47Å; A77-M98 VanDerWaalsContact CB-CE 3.47Å; A77-M98 HydrophobicContact CB-SD 3.66Å
78L96.9Very high96.8Very high4 Ų448 Ų482%0.02126%0.258CS..Hα-helixtrans-64.5-40-179.1-67.4-175.5000112.7I4 I7 I74 S80 K81 I91 L94 M95 V115I4-L78 HydrophobicContact CD1-CB 4.19Å; I7-L78 HydrophobicContact CD1-CB 4.22Å; I7-L78 HydrophobicContact CD1-CD1 3.91Å; I74-L78 HydrophobicContact CG2-CD1 3.72Å; I74-L78 HydrophobicContact CG2-CG 4.06Å; I74-L78 WeakPolarHBondContact O-CG 3.47Å; I74-L78 PolarHBondContact O-N 2.78Å; L78-S80 VanDerWaalsContact C-N 3.33Å; L78-S80 PolarHBondContact O-N 3.5Å; L78-K81 PolarHBondContact O-N 3.01Å; L78-I91 HydrophobicContact CD1-CG2 3.96Å; L78-I91 HydrophobicContact CD2-CG2 4.14Å; L78-L94 HydrophobicContact CD2-CB 4.2Å; L78-L94 HydrophobicContact CD2-CD1 4.35Å; L78-M95 HydrophobicContact CD1-CG 4.15Å; L78-M95 HydrophobicContact CD1-SD 4.07Å; L78-M95 HydrophobicContact CD2-CG 4.37Å; L78-V115 HydrophobicContact CD1-CG1 3.68Å
79V96.7Very high96.8Very high53 Ų5349.8 Ų49.832%0.32127%0.266SS..Hα-helixtrans-62.1-42.1175.3172.30000110.7I4 A75 A77 K81 D82I4-V79 HydrophobicContact CG2-CG2 3.91Å; A75-V79 WeakPolarHBondContact O-CB 3.46Å; A75-V79 VanDerWaalsContact O-CG2 3.25Å; A75-V79 WeakPolarHBondContact O-CG2 3.46Å; A75-V79 PolarHBondContact O-N 3.09Å; A75-V79 VanDerWaalsContact O-N 3.09Å; A77-V79 PolarHBondContact O-N 3.49Å; V79-K81 VanDerWaalsContact C-N 3.28Å; V79-K81 PolarHBondContact O-N 3.05Å; V79-D82 PolarHBondContact O-N 2.68Å
80S95.6Very high96.8Very high91 Ų9151.9 Ų51.964%0.63628%0.275SS*.Hα-helixtrans-68.6-23-179.474.40000114.6P76 A77 L78 D82P76-S80 VanDerWaalsContact O-CB 3.3Å; P76-S80 WeakPolarHBondContact O-CB 3.41Å; P76-S80 PolarHBondContact O-N 3.37Å; P76-S80 PolarHBondContact O-OG 2.96Å; A77-S80 PolarHBondContact O-N 3.28Å; A77-S80 PolarHBondContact O-OG 3.02Å; L78-S80 VanDerWaalsContact C-N 3.33Å; L78-S80 PolarHBondContact O-N 3.5Å; S80-D82 VanDerWaalsContact C-N 3.34Å
81K93Very high96.7Very high131 Ų13151.9 Ų51.957%0.5728%0.275SS*.THydrogen-bonded Turntrans-82.1-12.7-178.3-69.1-72.6-177.7-176.30113.3A77 L78 V79 V83 L94A77-K81 VanDerWaalsContact O-CG 3.28Å; A77-K81 WeakPolarHBondContact O-CG 3.29Å; A77-K81 PolarHBondContact O-N 3.21Å; L78-K81 PolarHBondContact O-N 3.01Å; V79-K81 VanDerWaalsContact C-N 3.28Å; V79-K81 PolarHBondContact O-N 3.05Å; K81-V83 HydrophobicContact CB-CG2 3.85Å; K81-V83 PolarHBondContact O-N 3.42Å; K81-V83 VanDerWaalsContact O-N 3.11Å; K81-L94 HydrophobicContact CG-CD1 4.49Å
82D88.6Confident96.7Very high113 Ų11349.7 Ų49.760%0.60426%0.263SS*.THydrogen-bonded Turntrans5134.1178.5-158.439.7000113.7S3 V79 S80S3-D82 WeakPolarHBondContact CB-OD1 3.48Å; S3-D82 PolarHBondContact OG-OD1 2.74Å; V79-D82 PolarHBondContact O-N 2.68Å; S80-D82 VanDerWaalsContact C-N 3.34Å
83V91.3Very high96.7Very high7 Ų748.2 Ų48.24%0.04226%0.256CS..  trans-76.7143.2178.8-177.10000109.6K81 E87 K90 I91 L94K81-V83 HydrophobicContact CB-CG2 3.85Å; K81-V83 PolarHBondContact O-N 3.42Å; K81-V83 VanDerWaalsContact O-N 3.11Å; V83-E87 HydrophobicContact CG1-CB 3.99Å; V83-E87 HydrophobicContact CG1-CG 4.5Å; V83-E87 WeakPolarHBondContact CG1-OE2 3.36Å; V83-K90 HydrophobicContact CG1-CB 4.46Å; V83-K90 HydrophobicContact CG1-CD 3.75Å; V83-K90 HydrophobicContact CG1-CG 4.12Å; V83-K90 HydrophobicContact CG2-CD 4.49Å; V83-I91 HydrophobicContact CB-CG1 4.18Å; V83-I91 HydrophobicContact CG1-CD1 4.12Å; V83-I91 HydrophobicContact CG1-CG1 3.66Å; V83-L94 HydrophobicContact CG2-CD1 3.89Å
84S95.5Very high96.7Very high5 Ų547.5 Ų47.54%0.03525%0.25CS..BIsolated β-bridgetrans-75.5139.3178.5-166.80000111.4M2 V86 E87 I91M2-S84 WeakPolarHBondContact O-CA 3.49Å; M2-S84 PolarHBondContact O-OG 3.01Å; M2-S84 VanDerWaalsContact O-OG 3.13Å; S84-V86 PolarHBondContact O-N 2.9Å; S84-E87 PolarHBondContact N-OE2 3.33Å; S84-E87 WeakPolarHBondContact O-CB 3.38Å; S84-E87 PolarHBondContact O-N 3.07Å; S84-I91 WeakPolarHBondContact O-CD1 3.47Å
85V96.9Very high96.7Very high0 Ų047.5 Ų47.50%025%0.25CS..THydrogen-bonded Turntrans-62.6-13.1179-66.90000114.5M2 I4 L25 T27 E87 A122 G123 E126M2-V85 PolarHBondContact O-N 3.39Å; I4-V85 HydrophobicContact CD1-CG1 4.37Å; I4-V85 HydrophobicContact CG1-CG1 3.57Å; L25-V85 HydrophobicContact CD2-CG1 4.18Å; T27-V85 HydrophobicContact CG2-CG1 3.92Å; T27-V85 HydrophobicContact CG2-CG2 4.43Å; V85-E87 VanDerWaalsContact C-N 3.35Å; V85-A122 HydrophobicContact CB-CB 4.01Å; V85-A122 HydrophobicContact CG1-CB 4.06Å; V85-A122 HydrophobicContact CG2-CB 4.15Å; V85-G123 WeakPolarHBondContact O-CA 3.32Å; V85-E126 HydrophobicContact CG2-CB 3.9Å; V85-E126 HydrophobicContact CG2-CG 4.28Å
86V97.4Very high96.7Very high41 Ų4149.2 Ų49.225%0.24826%0.258CS..THydrogen-bonded Turntrans-81.5-13.5172.9-57.80000113.2S84 Q88 E126 K127S84-V86 PolarHBondContact O-N 2.9Å; V86-Q88 VanDerWaalsContact C-N 3.28Å; V86-Q88 PolarHBondContact O-N 3.5Å; V86-Q88 VanDerWaalsContact O-N 3.17Å; V86-E126 HydrophobicContact CG1-CB 3.93Å; V86-E126 HydrophobicContact CG1-CG 3.72Å; V86-K127 HydrophobicContact CG1-CG 3.94Å
87E97.6Very high96.8Very high72 Ų7250.5 Ų50.534%0.33626%0.261SS..  trans-87.758.5178.6-60.1179.883.600110.9V83 S84 V85 E89 K90 I91V83-E87 HydrophobicContact CG1-CB 3.99Å; V83-E87 HydrophobicContact CG1-CG 4.5Å; V83-E87 WeakPolarHBondContact CG1-OE2 3.36Å; S84-E87 PolarHBondContact N-OE2 3.33Å; S84-E87 WeakPolarHBondContact O-CB 3.38Å; S84-E87 PolarHBondContact O-N 3.07Å; V85-E87 VanDerWaalsContact C-N 3.35Å; E87-E89 VanDerWaalsContact C-N 3.35Å; E87-E89 PolarHBondContact O-N 2.93Å; E87-K90 HydrophobicContact CB-CB 3.97Å; E87-K90 HydrophobicContact CB-CD 4.3Å; E87-K90 WeakPolarHBondContact O-CB 3.45Å; E87-K90 PolarHBondContact O-N 3.44Å; E87-K90 VanDerWaalsContact O-N 3.08Å; E87-K90 WeakPolarHBondContact OE1-CD 3.38Å; E87-K90 IonicContact OE1-NZ 2.74Å; E87-K90 PolarHBondContact OE1-NZ 3.15Å; E87-K90 IonicContact OE2-NZ 3.29Å; E87-K90 PolarHBondContact OE2-NZ 2.92Å; E87-I91 PolarHBondContact O-N 3.17Å
88Q98.7Very high96.8Very high1 Ų152 Ų521%0.00527%0.265CS..Hα-helixtrans-49.3-51.3-175.3-17668.145.600112.7V86 K90 I91 D92 S116 C120 L138 V351V86-Q88 VanDerWaalsContact C-N 3.28Å; V86-Q88 PolarHBondContact O-N 3.5Å; V86-Q88 VanDerWaalsContact O-N 3.17Å; Q88-K90 VanDerWaalsContact C-N 3.3Å; Q88-K90 PolarHBondContact O-N 2.99Å; Q88-I91 PolarHBondContact O-N 3.33Å; Q88-D92 VanDerWaalsContact NE2-CG 3.33Å; Q88-D92 PolarHBondContact NE2-OD1 3.43Å; Q88-D92 PolarHBondContact NE2-OD2 3.23Å; Q88-D92 WeakPolarHBondContact O-CB 3.22Å; Q88-D92 PolarHBondContact O-N 2.97Å; Q88-S116 PolarHBondContact NE2-O 3.43Å; Q88-S116 VanDerWaalsContact NE2-O 3.15Å; Q88-S116 PolarHBondContact NE2-OG 3.26Å; Q88-S116 VanDerWaalsContact NE2-OG 3.15Å; Q88-C120 VanDerWaalsContact OE1-CB 3.25Å; Q88-C120 VanDerWaalsContact OE1-N 3.15Å; Q88-L138 HydrophobicContact CB-CD1 3.97Å; Q88-L138 HydrophobicContact CB-CD2 3.96Å; Q88-L138 HydrophobicContact CG-CD1 4.09Å; Q88-V351 HydrophobicContact CG-CB 4.38Å; Q88-V351 HydrophobicContact CG-CG1 4.28Å
89E98.4Very high96.9Very high128 Ų12852 Ų5260%0.59827%0.265SS*.Hα-helixtrans-59.2-40.1-179.1176.4173.1-165.500112.4E87 K93 T352E87-E89 VanDerWaalsContact C-N 3.35Å; E87-E89 PolarHBondContact O-N 2.93Å; E89-K93 WeakPolarHBondContact O-CB 3.2Å; E89-K93 PolarHBondContact O-N 3.34Å; E89-T352 WeakPolarHBondContact CA-OG1 3.49Å; E89-T352 HydrophobicContact CB-CG2 4.1Å; E89-T352 HydrophobicContact CG-CG2 4.01Å
90K98.2Very high97Very high96 Ų9652.5 Ų52.542%0.41728%0.281SS..Hα-helixtrans-69.9-41.2179.8-175.1177170.8-172.80111.5V83 E87 Q88 L94V83-K90 HydrophobicContact CG1-CB 4.46Å; V83-K90 HydrophobicContact CG1-CD 3.75Å; V83-K90 HydrophobicContact CG1-CG 4.12Å; V83-K90 HydrophobicContact CG2-CD 4.49Å; E87-K90 HydrophobicContact CB-CB 3.97Å; E87-K90 HydrophobicContact CB-CD 4.3Å; E87-K90 WeakPolarHBondContact O-CB 3.45Å; E87-K90 PolarHBondContact O-N 3.44Å; E87-K90 VanDerWaalsContact O-N 3.08Å; E87-K90 WeakPolarHBondContact OE1-CD 3.38Å; E87-K90 IonicContact OE1-NZ 2.74Å; E87-K90 PolarHBondContact OE1-NZ 3.15Å; E87-K90 IonicContact OE2-NZ 3.29Å; E87-K90 PolarHBondContact OE2-NZ 2.92Å; Q88-K90 VanDerWaalsContact C-N 3.3Å; Q88-K90 PolarHBondContact O-N 2.99Å; K90-L94 VanDerWaalsContact O-CG 3.25Å; K90-L94 WeakPolarHBondContact O-CG 3.39Å; K90-L94 PolarHBondContact O-N 3.15Å
91I98.5Very high97.1Very high0 Ų050.6 Ų50.60%027%0.265CS..Hα-helixtrans-68.6-45.7178.5-67.1168.3000110.6I4 L78 V83 S84 E87 Q88 K93 L94 M95 V119I4-I91 HydrophobicContact CD1-CD1 4.25Å; L78-I91 HydrophobicContact CD1-CG2 3.96Å; L78-I91 HydrophobicContact CD2-CG2 4.14Å; V83-I91 HydrophobicContact CB-CG1 4.18Å; V83-I91 HydrophobicContact CG1-CD1 4.12Å; V83-I91 HydrophobicContact CG1-CG1 3.66Å; S84-I91 WeakPolarHBondContact O-CD1 3.47Å; E87-I91 PolarHBondContact O-N 3.17Å; Q88-I91 PolarHBondContact O-N 3.33Å; I91-K93 VanDerWaalsContact C-N 3.35Å; I91-K93 PolarHBondContact O-N 3.36Å; I91-L94 PolarHBondContact O-N 2.88Å; I91-M95 HydrophobicContact CG2-CE 4.26Å; I91-M95 PolarHBondContact O-N 2.88Å; I91-M95 VanDerWaalsContact O-N 3.14Å; I91-V119 HydrophobicContact CB-CG1 4.35Å; I91-V119 HydrophobicContact CD1-CG1 3.52Å; I91-V119 HydrophobicContact CD1-CG2 4.39Å; I91-V119 HydrophobicContact CG2-CG1 4.26Å; I91-V119 HydrophobicContact CG2-CG2 3.92Å
92D98.8Very high97.1Very high0 Ų051.6 Ų51.60%027%0.272CS..Hα-helixtrans-59-47.9175.1-74.3-20.7000110.4Q88 L94 M95 L96 S116 T352Q88-D92 VanDerWaalsContact NE2-CG 3.33Å; Q88-D92 PolarHBondContact NE2-OD1 3.43Å; Q88-D92 PolarHBondContact NE2-OD2 3.23Å; Q88-D92 WeakPolarHBondContact O-CB 3.22Å; Q88-D92 PolarHBondContact O-N 2.97Å; D92-L94 VanDerWaalsContact C-N 3.32Å; D92-L94 PolarHBondContact O-N 3.28Å; D92-M95 PolarHBondContact O-N 3.07Å; D92-M95 VanDerWaalsContact O-N 3.1Å; D92-M95 WeakPolarHBondContact OD1-CE 3.4Å; D92-L96 VanDerWaalsContact O-CG 3.26Å; D92-L96 WeakPolarHBondContact O-CG 3.18Å; D92-L96 PolarHBondContact O-N 3.03Å; D92-S116 VanDerWaalsContact CG-OG 3.23Å; D92-S116 WeakPolarHBondContact OD1-CB 3.4Å; D92-S116 PolarHBondContact OD1-OG 2.86Å; D92-S116 PolarHBondContact OD2-OG 3.05Å; D92-T352 WeakPolarHBondContact OD2-CB 3.02Å; D92-T352 PolarHBondContact OD2-N 2.86Å; D92-T352 PolarHBondContact OD2-OG1 3.02Å
93K98.6Very high97.3Very high112 Ų11249.3 Ų49.349%0.48726%0.26SS..Hα-helixtrans-56.6-42.9176.3177.7163.7176.942.70113E89 I91 M95 L96 D97E89-K93 WeakPolarHBondContact O-CB 3.2Å; E89-K93 PolarHBondContact O-N 3.34Å; I91-K93 VanDerWaalsContact C-N 3.35Å; I91-K93 PolarHBondContact O-N 3.36Å; K93-M95 VanDerWaalsContact C-N 3.33Å; K93-M95 PolarHBondContact O-N 3.38Å; K93-L96 PolarHBondContact O-N 3.16Å; K93-D97 WeakPolarHBondContact CE-OD2 3.25Å; K93-D97 WeakPolarHBondContact CG-OD2 3.3Å; K93-D97 VanDerWaalsContact NZ-CG 3.25Å; K93-D97 IonicContact NZ-OD1 3.07Å; K93-D97 PolarHBondContact NZ-OD1 2.6Å; K93-D97 IonicContact NZ-OD2 3.83Å; K93-D97 PolarHBondContact NZ-OD2 2.95Å; K93-D97 WeakPolarHBondContact O-CB 3.35Å; K93-D97 PolarHBondContact O-N 3.17Å
94L98.3Very high97.6Very high43 Ų4349.2 Ų49.223%0.22526%0.259CS..Hα-helixtrans-60.3-42.9176.9-75.2168.8000111.7L78 K81 V83 K90 I91 D92 M98L78-L94 HydrophobicContact CD2-CB 4.2Å; L78-L94 HydrophobicContact CD2-CD1 4.35Å; K81-L94 HydrophobicContact CG-CD1 4.49Å; V83-L94 HydrophobicContact CG2-CD1 3.89Å; K90-L94 VanDerWaalsContact O-CG 3.25Å; K90-L94 WeakPolarHBondContact O-CG 3.39Å; K90-L94 PolarHBondContact O-N 3.15Å; I91-L94 PolarHBondContact O-N 2.88Å; D92-L94 VanDerWaalsContact C-N 3.32Å; D92-L94 PolarHBondContact O-N 3.28Å; L94-M98 WeakPolarHBondContact O-CB 3.46Å; L94-M98 WeakPolarHBondContact O-CG 3.47Å; L94-M98 PolarHBondContact O-N 2.61Å
95M98.7Very high97.7Very high0 Ų051.2 Ų51.20%027%0.273CS..Hα-helixtrans-66.6-41.4177.5-65.5-172.2-68.500112I74 L78 I91 D92 K93 M98 D99 I112 V115I74-M95 HydrophobicContact CG2-CG 4.03Å; I74-M95 HydrophobicContact CG2-SD 3.87Å; L78-M95 HydrophobicContact CD1-CG 4.15Å; L78-M95 HydrophobicContact CD1-SD 4.07Å; L78-M95 HydrophobicContact CD2-CG 4.37Å; I91-M95 HydrophobicContact CG2-CE 4.26Å; I91-M95 PolarHBondContact O-N 2.88Å; I91-M95 VanDerWaalsContact O-N 3.14Å; D92-M95 PolarHBondContact O-N 3.07Å; D92-M95 VanDerWaalsContact O-N 3.1Å; D92-M95 WeakPolarHBondContact OD1-CE 3.4Å; K93-M95 VanDerWaalsContact C-N 3.33Å; K93-M95 PolarHBondContact O-N 3.38Å; M95-M98 PolarHBondContact O-N 3.18Å; M95-D99 WeakPolarHBondContact O-CB 3.3Å; M95-D99 PolarHBondContact O-N 2.57Å; M95-I112 HydrophobicContact CB-CG2 4.04Å; M95-I112 HydrophobicContact CE-CG2 3.99Å; M95-I112 HydrophobicContact SD-CG2 4.31Å; M95-V115 HydrophobicContact CE-CB 4.34Å; M95-V115 HydrophobicContact CE-CG1 4.23Å; M95-V115 HydrophobicContact SD-CB 3.67Å; M95-V115 HydrophobicContact SD-CG1 3.55Å; M95-V115 VanDerWaalsContact SD-CG1 3.55Å; M95-V115 HydrophobicContact SD-CG2 4.46Å
96L98.6Very high97.7Very high43 Ų4356.4 Ų56.423%0.22530%0.296CS..Hα-helixtrans-62.4-45.7176.2-64.8173.4000111.8D92 K93 M98 D99 G100 K104 E353D92-L96 VanDerWaalsContact O-CG 3.26Å; D92-L96 WeakPolarHBondContact O-CG 3.18Å; D92-L96 PolarHBondContact O-N 3.03Å; K93-L96 PolarHBondContact O-N 3.16Å; L96-M98 VanDerWaalsContact C-N 3.32Å; L96-M98 PolarHBondContact O-N 3.37Å; L96-D99 PolarHBondContact O-N 3.11Å; L96-G100 PolarHBondContact O-N 3.43Å; L96-K104 HydrophobicContact CD2-CD 4.33Å; L96-K104 HydrophobicContact CD2-CG 4.38Å; L96-E353 HydrophobicContact CD1-CG 4.28Å
97D98.4Very high97.8Very high97 Ų9754.8 Ų54.852%0.51929%0.285SS..Hα-helixtrans-66-35.3178.3-67.8-17.2000111.5K93K93-D97 WeakPolarHBondContact CE-OD2 3.25Å; K93-D97 WeakPolarHBondContact CG-OD2 3.3Å; K93-D97 VanDerWaalsContact NZ-CG 3.25Å; K93-D97 IonicContact NZ-OD1 3.07Å; K93-D97 PolarHBondContact NZ-OD1 2.6Å; K93-D97 IonicContact NZ-OD2 3.83Å; K93-D97 PolarHBondContact NZ-OD2 2.95Å; K93-D97 WeakPolarHBondContact O-CB 3.35Å; K93-D97 PolarHBondContact O-N 3.17Å
98M98.3Very high97.8Very high55 Ų5551.3 Ų51.327%0.27127%0.269SS..Hα-helixtrans-70.7-36.1175.8-75.9174.156.200113.3T73 A77 L94 M95 L96 K106 F107T73-M98 HydrophobicContact CG2-CE 4.03Å; A77-M98 HydrophobicContact CB-CE 3.47Å; A77-M98 VanDerWaalsContact CB-CE 3.47Å; A77-M98 HydrophobicContact CB-SD 3.66Å; L94-M98 WeakPolarHBondContact O-CB 3.46Å; L94-M98 WeakPolarHBondContact O-CG 3.47Å; L94-M98 PolarHBondContact O-N 2.61Å; M95-M98 PolarHBondContact O-N 3.18Å; L96-M98 VanDerWaalsContact C-N 3.32Å; L96-M98 PolarHBondContact O-N 3.37Å; M98-K106 PolarHBondContact O-NZ 3.32Å; M98-F107 HydrophobicContact CB-CE2 3.7Å; M98-F107 HydrophobicContact CB-CZ 4.09Å; M98-F107 HydrophobicContact CE-CE2 4.38Å; M98-F107 HydrophobicContact CE-CZ 4.35Å
99D98.6Very high97.7Very high4 Ų451.4 Ų51.42%0.02127%0.27CS..Hα-helixtrans-66.4-52.8172.2-179-80.5000109.7M95 L96 T101 K104 K106 F107 I112M95-D99 WeakPolarHBondContact O-CB 3.3Å; M95-D99 PolarHBondContact O-N 2.57Å; L96-D99 PolarHBondContact O-N 3.11Å; D99-T101 PolarHBondContact O-N 3.12Å; D99-T101 WeakPolarHBondContact OD1-CB 3.46Å; D99-T101 PolarHBondContact OD1-N 3.09Å; D99-T101 PolarHBondContact OD1-OG1 3.47Å; D99-K104 WeakPolarHBondContact OD1-CA 3.31Å; D99-K106 WeakPolarHBondContact O-CD 3.26Å; D99-K106 WeakPolarHBondContact OD2-CB 3.38Å; D99-K106 PolarHBondContact OD2-N 3.32Å; D99-F107 HydrophobicContact CB-CD2 3.7Å; D99-F107 HydrophobicContact CB-CE2 4.03Å; D99-F107 HydrophobicContact CB-CG 4.38Å; D99-F107 PolarHBondContact OD2-N 3.49Å; D99-I112 HydrophobicContact CB-CD1 3.93Å
100G98.1Very high97.7Very high64 Ų6445.5 Ų45.566%0.6624%0.242SC*.  trans73.27.5173.300000115L96L96-G100 PolarHBondContact O-N 3.43Å
101T97.7Very high97.8Very high50 Ų5040.9 Ų40.931%0.30722%0.222SC..SBendtrans-109.4151.8176.874.80000111.4D99 N103 K104 S105 K106D99-T101 PolarHBondContact O-N 3.12Å; D99-T101 WeakPolarHBondContact OD1-CB 3.46Å; D99-T101 PolarHBondContact OD1-N 3.09Å; D99-T101 PolarHBondContact OD1-OG1 3.47Å; T101-N103 VanDerWaalsContact C-N 3.32Å; T101-N103 PolarHBondContact O-N 3.02Å; T101-K104 VanDerWaalsContact OG1-CA 3.3Å; T101-K104 WeakPolarHBondContact OG1-CA 3.37Å; T101-K104 PolarHBondContact OG1-N 3.49Å; T101-S105 PolarHBondContact OG1-N 3.48Å; T101-S105 PolarHBondContact OG1-OG 2.94Å; T101-K106 HydrophobicContact CG2-CB 3.95Å
102E93.8Very high97.8Very high152 Ų15240.9 Ų40.971%0.7122%0.222SC*.THydrogen-bonded Turntrans-64.1-36.9-178.8-178.2171.2-167.800112.7K327E102-K327 IonicContact OE1-NZ 2.97Å; E102-K327 PolarHBondContact OE1-NZ 3.04Å
103N93.8Very high97.8Very high65 Ų6540.9 Ų40.935%0.34822%0.222SC..THydrogen-bonded Turntrans-107.917.4-174.767.3-17.9000113.4L48 T101 S105L48-N103 PolarHBondContact N-O 3.46Å; T101-N103 VanDerWaalsContact C-N 3.32Å; T101-N103 PolarHBondContact O-N 3.02Å; N103-S105 PolarHBondContact O-N 3.22Å; N103-S105 WeakPolarHBondContact OD1-CB 3.17Å; N103-S105 PolarHBondContact OD1-N 2.94Å; N103-S105 PolarHBondContact OD1-OG 3.49Å
104K97.8Very high97.8Very high5 Ų535.6 Ų35.62%0.02220%0.199CC..  trans59.828178.6-56.1171.3169.666.50113.4A47 L96 D99 T101 K106 G108 A109 I112 I348 E353A47-K104 HydrophobicContact CB-CD 4.07Å; L96-K104 HydrophobicContact CD2-CD 4.33Å; L96-K104 HydrophobicContact CD2-CG 4.38Å; D99-K104 WeakPolarHBondContact OD1-CA 3.31Å; T101-K104 VanDerWaalsContact OG1-CA 3.3Å; T101-K104 WeakPolarHBondContact OG1-CA 3.37Å; T101-K104 PolarHBondContact OG1-N 3.49Å; K104-K106 VanDerWaalsContact C-N 3.31Å; K104-K106 PolarHBondContact O-N 3.48Å; K104-G108 CarbonylContact O-C 3.42Å; K104-G108 WeakPolarHBondContact O-CA 3.25Å; K104-G108 PolarHBondContact O-N 3.14Å; K104-A109 HydrophobicContact CB-CB 4.24Å; K104-A109 HydrophobicContact CD-CB 4.11Å; K104-I112 HydrophobicContact CB-CD1 3.97Å; K104-I112 HydrophobicContact CD-CD1 4.07Å; K104-I112 HydrophobicContact CG-CD1 3.88Å; K104-I348 WeakPolarHBondContact CD-O 3.46Å; K104-I348 WeakPolarHBondContact CE-O 3.38Å; K104-I348 PolarHBondContact NZ-O 2.84Å; K104-E353 WeakPolarHBondContact CE-OE2 3.45Å; K104-E353 IonicContact NZ-OE1 3.01Å; K104-E353 PolarHBondContact NZ-OE1 3.45Å; K104-E353 IonicContact NZ-OE2 3.03Å; K104-E353 PolarHBondContact NZ-OE2 2.85Å
105S96.6Very high97.8Very high47 Ų4733.5 Ų33.533%0.32919%0.188SC..THydrogen-bonded Turntrans-75.2-14.8-172.351.50000114.3T101 N103T101-S105 PolarHBondContact OG1-N 3.48Å; T101-S105 PolarHBondContact OG1-OG 2.94Å; N103-S105 PolarHBondContact O-N 3.22Å; N103-S105 WeakPolarHBondContact OD1-CB 3.17Å; N103-S105 PolarHBondContact OD1-N 2.94Å; N103-S105 PolarHBondContact OD1-OG 3.49Å
106K97.6Very high97.8Very high110 Ų11033.5 Ų33.548%0.47819%0.188SC..THydrogen-bonded Turntrans-76.2-48178.4-180-172.9177.5-173.40111.7H69 M98 D99 T101 K104H69-K106 PolarHBondContact NE2-O 3.1Å; M98-K106 PolarHBondContact O-NZ 3.32Å; D99-K106 WeakPolarHBondContact O-CD 3.26Å; D99-K106 WeakPolarHBondContact OD2-CB 3.38Å; D99-K106 PolarHBondContact OD2-N 3.32Å; T101-K106 HydrophobicContact CG2-CB 3.95Å; K104-K106 VanDerWaalsContact C-N 3.31Å; K104-K106 PolarHBondContact O-N 3.48Å
107F98.2Very high97.9Very high6 Ų631.7 Ų31.73%0.02618%0.179CC..THydrogen-bonded Turntrans-97-24.2178.1-62.3-29.6000113.3L50 H69 T73 I74 M98 D99 A111 I112L50-F107 WeakPolarHBondContact CD2-O 3.41Å; H69-F107 HydrophobicContact CB-CB 4.4Å; H69-F107 HydrophobicContact CB-CD1 4.11Å; H69-F107 AromaticContact CG-CD1 3.91Å; H69-F107 AromaticContact ND1-CD1 3.86Å; T73-F107 HydrophobicContact CG2-CE1 3.99Å; T73-F107 HydrophobicContact CG2-CZ 3.88Å; I74-F107 HydrophobicContact CD1-CB 4.45Å; I74-F107 HydrophobicContact CD1-CD2 4Å; I74-F107 HydrophobicContact CD1-CG 4.32Å; I74-F107 HydrophobicContact CG1-CD2 4.16Å; I74-F107 HydrophobicContact CG1-CE2 4.21Å; M98-F107 HydrophobicContact CB-CE2 3.7Å; M98-F107 HydrophobicContact CB-CZ 4.09Å; M98-F107 HydrophobicContact CE-CE2 4.38Å; M98-F107 HydrophobicContact CE-CZ 4.35Å; D99-F107 HydrophobicContact CB-CD2 3.7Å; D99-F107 HydrophobicContact CB-CE2 4.03Å; D99-F107 HydrophobicContact CB-CG 4.38Å; D99-F107 PolarHBondContact OD2-N 3.49Å; F107-A111 HydrophobicContact CB-CB 4.25Å; F107-A111 WeakPolarHBondContact O-CB 3.49Å; F107-I112 HydrophobicContact CB-CG1 4.35Å; F107-I112 HydrophobicContact CD2-CG1 4.47Å
108G98.1Very high97.9Very high0 Ų027 Ų270%015%0.154CC..  trans90.2135-166.100000111.6L48 K104 N110 A111 I112L48-G108 CarbonylContact O-C 3.56Å; L48-G108 WeakPolarHBondContact O-CA 3.35Å; K104-G108 CarbonylContact O-C 3.42Å; K104-G108 WeakPolarHBondContact O-CA 3.25Å; K104-G108 PolarHBondContact O-N 3.14Å; G108-N110 WeakPolarHBondContact CA-OD1 3.48Å; G108-N110 PolarHBondContact O-N 3.38Å; G108-A111 WeakPolarHBondContact O-CB 3.42Å; G108-A111 PolarHBondContact O-N 3.44Å; G108-I112 PolarHBondContact O-N 3.25Å
109A97.9Very high97.9Very high3 Ų324.4 Ų24.43%0.02514%0.141CC..Hα-helixtrans-57.4-33.317300000111.8A47 L48 K104 A111 I112 L113A47-A109 HydrophobicContact CB-CB 3.62Å; L48-A109 WeakPolarHBondContact O-CB 3.47Å; L48-A109 PolarHBondContact O-N 2.93Å; K104-A109 HydrophobicContact CB-CB 4.24Å; K104-A109 HydrophobicContact CD-CB 4.11Å; A109-A111 VanDerWaalsContact C-N 3.35Å; A109-A111 PolarHBondContact O-N 3.24Å; A109-I112 PolarHBondContact O-N 3.01Å; A109-L113 WeakPolarHBondContact O-CB 3.34Å; A109-L113 PolarHBondContact O-N 3.46Å
110N98.3Very high97.9Very high3 Ų324.2 Ų24.22%0.01614%0.14CC..Hα-helixtrans-65.5-32.7173.955.1-17.7000113.5V21 V36 E49 L50 G108 G114V21-N110 HydrophobicContact CG2-CB 4.27Å; V36-N110 HydrophobicContact CG1-CB 3.95Å; V36-N110 WeakPolarHBondContact CG2-O 3.33Å; E49-N110 HydrophobicContact CG-CB 4.08Å; E49-N110 WeakPolarHBondContact CG-ND2 3.27Å; L50-N110 PolarHBondContact N-OD1 3.35Å; L50-N110 PolarHBondContact O-ND2 3.3Å; G108-N110 WeakPolarHBondContact CA-OD1 3.48Å; G108-N110 PolarHBondContact O-N 3.38Å; N110-G114 PolarHBondContact O-N 2.75Å
111A98.8Very high98Very high0 Ų023 Ų230%012%0.117CC..Hα-helixtrans-69.7-49.6174.900000111.7A66 I70 I74 F107 G108 A109A66-A111 HydrophobicContact CB-CB 4.26Å; I70-A111 HydrophobicContact CD1-CB 4.13Å; I70-A111 HydrophobicContact CG1-CB 3.82Å; I74-A111 HydrophobicContact CD1-CB 4.35Å; F107-A111 HydrophobicContact CB-CB 4.25Å; F107-A111 WeakPolarHBondContact O-CB 3.49Å; G108-A111 WeakPolarHBondContact O-CB 3.42Å; G108-A111 PolarHBondContact O-N 3.44Å; A109-A111 VanDerWaalsContact C-N 3.35Å; A109-A111 PolarHBondContact O-N 3.24Å
112I98.9Very high98Very high0 Ų020.7 Ų20.70%010%0.102CC..Hα-helixtrans-64.7-46.5-178.1-62177.9000110.4M95 D99 K104 F107 G108 A109 G114 V115 S116 G349M95-I112 HydrophobicContact CB-CG2 4.04Å; M95-I112 HydrophobicContact CE-CG2 3.99Å; M95-I112 HydrophobicContact SD-CG2 4.31Å; D99-I112 HydrophobicContact CB-CD1 3.93Å; K104-I112 HydrophobicContact CB-CD1 3.97Å; K104-I112 HydrophobicContact CD-CD1 4.07Å; K104-I112 HydrophobicContact CG-CD1 3.88Å; F107-I112 HydrophobicContact CB-CG1 4.35Å; F107-I112 HydrophobicContact CD2-CG1 4.47Å; G108-I112 PolarHBondContact O-N 3.25Å; A109-I112 PolarHBondContact O-N 3.01Å; I112-G114 PolarHBondContact O-N 2.86Å; I112-V115 PolarHBondContact O-N 2.87Å; I112-S116 WeakPolarHBondContact O-CB 3.44Å; I112-S116 PolarHBondContact O-N 3.34Å; I112-G349 WeakPolarHBondContact CG2-O 3.33Å
113L98.9Very high98.2Very high0 Ų013.4 Ų13.40%07%0.068CC..Hα-helixtrans-63-43.9-177.2-175.466.7000111.9V36 A109 V115 S116 L117 V345 N346 G349V36-L113 HydrophobicContact CG1-CD2 3.9Å; V36-L113 HydrophobicContact CG2-CB 4.29Å; V36-L113 HydrophobicContact CG2-CD2 4.34Å; V36-L113 HydrophobicContact CG2-CG 4.38Å; A109-L113 WeakPolarHBondContact O-CB 3.34Å; A109-L113 PolarHBondContact O-N 3.46Å; L113-V115 VanDerWaalsContact C-N 3.27Å; L113-V115 PolarHBondContact O-N 3Å; L113-S116 WeakPolarHBondContact O-CB 3.39Å; L113-S116 PolarHBondContact O-N 3.36Å; L113-S116 VanDerWaalsContact O-N 3.09Å; L113-L117 HydrophobicContact CD1-CD1 4.31Å; L113-L117 HydrophobicContact CD1-CD2 4.13Å; L113-L117 HydrophobicContact CD1-CG 3.98Å; L113-L117 HydrophobicContact CD2-CD1 4.33Å; L113-L117 HydrophobicContact CG-CD1 3.89Å; L113-L117 HydrophobicContact CG-CG 4.01Å; L113-L117 VanDerWaalsContact O-CG 3.25Å; L113-L117 WeakPolarHBondContact O-CG 3.42Å; L113-L117 PolarHBondContact O-N 2.8Å; L113-V345 HydrophobicContact CD1-CB 4.23Å; L113-V345 HydrophobicContact CD1-CG2 4.43Å; L113-V345 HydrophobicContact CD2-CG2 4.15Å; L113-N346 VanDerWaalsContact CD2-CA 3.46Å; L113-N346 HydrophobicContact CD2-CB 3.43Å; L113-N346 VanDerWaalsContact CD2-CB 3.43Å; L113-G349 WeakPolarHBondContact CA-O 3.27Å; L113-G349 PolarHBondContact N-O 3.29Å
114G98.8Very high98.5Very high0 Ų010.5 Ų10.50%05%0.053CC..Hα-helixtrans-56.9-42.6-179.400000112.3V36 N110 I112 A118V36-G114 VanDerWaalsContact CG2-CA 3.47Å; N110-G114 PolarHBondContact O-N 2.75Å; I112-G114 PolarHBondContact O-N 2.86Å; G114-A118 WeakPolarHBondContact O-CB 3.32Å; G114-A118 PolarHBondContact O-N 3.04Å
115V98.9Very high98.5Very high0 Ų011.8 Ų11.80%07%0.065CC..Hα-helixtrans-68.5-45.6174.7179.50000111I7 V23 I70 I74 L78 M95 I112 L113 L117 A118 V119I7-V115 HydrophobicContact CD1-CG1 4.03Å; I7-V115 HydrophobicContact CG2-CG2 4.35Å; V23-V115 HydrophobicContact CG1-CG2 4.12Å; V23-V115 HydrophobicContact CG2-CG2 4.34Å; I70-V115 HydrophobicContact CD1-CG2 4.45Å; I70-V115 HydrophobicContact CG1-CG2 4.16Å; I70-V115 HydrophobicContact CG2-CG2 3.78Å; I74-V115 HydrophobicContact CG2-CG1 4.38Å; I74-V115 HydrophobicContact CG2-CG2 4.18Å; L78-V115 HydrophobicContact CD1-CG1 3.68Å; M95-V115 HydrophobicContact CE-CB 4.34Å; M95-V115 HydrophobicContact CE-CG1 4.23Å; M95-V115 HydrophobicContact SD-CB 3.67Å; M95-V115 HydrophobicContact SD-CG1 3.55Å; M95-V115 VanDerWaalsContact SD-CG1 3.55Å; M95-V115 HydrophobicContact SD-CG2 4.46Å; I112-V115 PolarHBondContact O-N 2.87Å; L113-V115 VanDerWaalsContact C-N 3.27Å; L113-V115 PolarHBondContact O-N 3Å; V115-L117 VanDerWaalsContact C-N 3.33Å; V115-L117 PolarHBondContact O-N 3.3Å; V115-A118 PolarHBondContact O-N 2.91Å; V115-V119 HydrophobicContact CG1-CG2 4.14Å; V115-V119 WeakPolarHBondContact O-CB 3.44Å; V115-V119 VanDerWaalsContact O-CG2 3.22Å; V115-V119 WeakPolarHBondContact O-CG2 3.34Å; V115-V119 PolarHBondContact O-N 3.12Å
116S98.9Very high98.6Very high0 Ų011.6 Ų11.60%06%0.059CC..Hα-helixtrans-55.4-44.7179.5-171.90000112.7Q88 D92 I112 L113 C120 V351Q88-S116 PolarHBondContact NE2-O 3.43Å; Q88-S116 VanDerWaalsContact NE2-O 3.15Å; Q88-S116 PolarHBondContact NE2-OG 3.26Å; Q88-S116 VanDerWaalsContact NE2-OG 3.15Å; D92-S116 VanDerWaalsContact CG-OG 3.23Å; D92-S116 WeakPolarHBondContact OD1-CB 3.4Å; D92-S116 PolarHBondContact OD1-OG 2.86Å; D92-S116 PolarHBondContact OD2-OG 3.05Å; I112-S116 WeakPolarHBondContact O-CB 3.44Å; I112-S116 PolarHBondContact O-N 3.34Å; L113-S116 WeakPolarHBondContact O-CB 3.39Å; L113-S116 PolarHBondContact O-N 3.36Å; L113-S116 VanDerWaalsContact O-N 3.09Å; S116-C120 PolarHBondContact O-N 3.23Å; S116-C120 VanDerWaalsContact O-N 3.07Å; S116-V351 WeakPolarHBondContact OG-CG2 3.25Å; S116-V351 PolarHBondContact OG-N 3.35Å
117L98.9Very high98.6Very high4 Ų410.6 Ų10.62%0.0215%0.054CC..Hα-helixtrans-67.1-43.5177.2-63.7175.8000112.1A34 L113 V115 V119 C120 K121 V351 F381A34-L117 HydrophobicContact CB-CB 3.39Å; A34-L117 HydrophobicContact CB-CD1 4.29Å; A34-L117 HydrophobicContact CB-CG 4.5Å; L113-L117 HydrophobicContact CD1-CD1 4.31Å; L113-L117 HydrophobicContact CD1-CD2 4.13Å; L113-L117 HydrophobicContact CD1-CG 3.98Å; L113-L117 HydrophobicContact CD2-CD1 4.33Å; L113-L117 HydrophobicContact CG-CD1 3.89Å; L113-L117 HydrophobicContact CG-CG 4.01Å; L113-L117 VanDerWaalsContact O-CG 3.25Å; L113-L117 WeakPolarHBondContact O-CG 3.42Å; L113-L117 PolarHBondContact O-N 2.8Å; V115-L117 VanDerWaalsContact C-N 3.33Å; V115-L117 PolarHBondContact O-N 3.3Å; L117-V119 VanDerWaalsContact C-N 3.33Å; L117-V119 PolarHBondContact O-N 2.91Å; L117-C120 PolarHBondContact O-N 3.33Å; L117-K121 WeakPolarHBondContact O-CG 3.44Å; L117-K121 PolarHBondContact O-N 3.2Å; L117-V351 HydrophobicContact CD2-CG2 3.72Å; L117-F381 HydrophobicContact CB-CD2 4.4Å; L117-F381 HydrophobicContact CB-CE2 4.44Å; L117-F381 HydrophobicContact CD2-CD1 3.46Å; L117-F381 VanDerWaalsContact CD2-CD1 3.46Å; L117-F381 HydrophobicContact CD2-CD2 3.73Å; L117-F381 HydrophobicContact CD2-CE1 3.35Å; L117-F381 HydrophobicContact CD2-CE2 3.63Å; L117-F381 HydrophobicContact CD2-CG 3.66Å; L117-F381 HydrophobicContact CD2-CZ 3.44Å; L117-F381 VanDerWaalsContact CD2-CZ 3.44Å
118A98.9Very high98.6Very high0 Ų013.5 Ų13.50%09%0.086CC..Hα-helixtrans-66-36178.600000112V23 L25 A34 G114 V115 K121 A122V23-A118 HydrophobicContact CB-CB 4.46Å; V23-A118 HydrophobicContact CG1-CB 4.22Å; L25-A118 HydrophobicContact CB-CB 3.87Å; A34-A118 HydrophobicContact CB-CB 4.13Å; G114-A118 WeakPolarHBondContact O-CB 3.32Å; G114-A118 PolarHBondContact O-N 3.04Å; V115-A118 PolarHBondContact O-N 2.91Å; A118-K121 PolarHBondContact O-N 2.95Å; A118-A122 WeakPolarHBondContact O-CB 3.43Å; A118-A122 PolarHBondContact O-N 2.98Å
119V98.8Very high98.6Very high0 Ų015.7 Ų15.70%010%0.099CC..Hα-helixtrans-61.8-47.9171.71700000110.6L25 I91 V115 L117 K121 A122 G123L25-V119 HydrophobicContact CD1-CB 4.34Å; L25-V119 HydrophobicContact CD1-CG2 3.42Å; L25-V119 VanDerWaalsContact CD1-CG2 3.42Å; I91-V119 HydrophobicContact CB-CG1 4.35Å; I91-V119 HydrophobicContact CD1-CG1 3.52Å; I91-V119 HydrophobicContact CD1-CG2 4.39Å; I91-V119 HydrophobicContact CG2-CG1 4.26Å; I91-V119 HydrophobicContact CG2-CG2 3.92Å; V115-V119 HydrophobicContact CG1-CG2 4.14Å; V115-V119 WeakPolarHBondContact O-CB 3.44Å; V115-V119 VanDerWaalsContact O-CG2 3.22Å; V115-V119 WeakPolarHBondContact O-CG2 3.34Å; V115-V119 PolarHBondContact O-N 3.12Å; L117-V119 VanDerWaalsContact C-N 3.33Å; L117-V119 PolarHBondContact O-N 2.91Å; V119-K121 VanDerWaalsContact C-N 3.32Å; V119-K121 PolarHBondContact O-N 3.38Å; V119-A122 CarbonylContact O-C 3.57Å; V119-A122 WeakPolarHBondContact O-CB 3.27Å; V119-A122 PolarHBondContact O-N 3.11Å; V119-A122 VanDerWaalsContact O-N 3.09Å; V119-G123 PolarHBondContact O-N 3.38Å
120C98.9Very high98.7Very high0 Ų017.5 Ų17.50%011%0.111CC..Hα-helixtrans-59.4-42.7179.2-172.10000111.9Q88 S116 L117 A122 G123 A124 H134 V351 F381Q88-C120 VanDerWaalsContact OE1-CB 3.25Å; Q88-C120 VanDerWaalsContact OE1-N 3.15Å; S116-C120 PolarHBondContact O-N 3.23Å; S116-C120 VanDerWaalsContact O-N 3.07Å; L117-C120 PolarHBondContact O-N 3.33Å; C120-A122 PolarHBondContact O-N 3.38Å; C120-G123 PolarHBondContact O-N 3.47Å; C120-A124 PolarHBondContact O-N 3.17Å; C120-H134 PolarHBondContact O-CD2 3.19Å; C120-H134 VanDerWaalsContact O-CD2 3.23Å; C120-V351 HydrophobicContact CB-CG2 4.3Å; C120-F381 HydrophobicContact CB-CE2 3.99Å; C120-F381 HydrophobicContact CB-CZ 4.34Å
121K98.9Very high98.7Very high39 Ų3918.5 Ų18.517%0.1712%0.116CC..Hα-helixtrans-60.7-44173.3-72.1175.1177.6179.10112.3F32 R33 A34 L117 A118 V119 A124 A125 L131 D379F32-K121 HydrophobicContact CB-CB 4.12Å; F32-K121 HydrophobicContact CD1-CB 4.29Å; R33-K121 WeakPolarHBondContact O-CD 3.39Å; R33-K121 WeakPolarHBondContact O-CE 3.27Å; R33-K121 PolarHBondContact O-NZ 2.89Å; A34-K121 HydrophobicContact CB-CD 4.42Å; L117-K121 WeakPolarHBondContact O-CG 3.44Å; L117-K121 PolarHBondContact O-N 3.2Å; A118-K121 PolarHBondContact O-N 2.95Å; V119-K121 VanDerWaalsContact C-N 3.32Å; V119-K121 PolarHBondContact O-N 3.38Å; K121-A124 PolarHBondContact O-N 3.34Å; K121-A125 PolarHBondContact O-N 3.16Å; K121-L131 HydrophobicContact CG-CD1 4.35Å; K121-L131 HydrophobicContact CG-CD2 4.01Å; K121-D379 IonicContact NZ-OD1 3.35Å; K121-D379 PolarHBondContact NZ-OD1 2.62Å; K121-D379 IonicContact NZ-OD2 3.47Å; K121-D379 PolarHBondContact NZ-OD2 3.45Å
122A98.8Very high98.7Very high0 Ų019.2 Ų19.20%012%0.119CC..Hα-helixtrans-66.6-37.4176.200000112.6L25 T27 F32 V85 A118 V119 C120 A124 A125 E126L25-A122 HydrophobicContact CD2-CB 3.75Å; T27-A122 HydrophobicContact CG2-CB 4.1Å; F32-A122 HydrophobicContact CB-CB 4.13Å; F32-A122 HydrophobicContact CD1-CB 4.28Å; F32-A122 HydrophobicContact CD2-CB 3.37Å; F32-A122 HydrophobicContact CE2-CB 3.83Å; F32-A122 HydrophobicContact CG-CB 3.62Å; F32-A122 HydrophobicContact CZ-CB 4.46Å; V85-A122 HydrophobicContact CB-CB 4.01Å; V85-A122 HydrophobicContact CG1-CB 4.06Å; V85-A122 HydrophobicContact CG2-CB 4.15Å; A118-A122 WeakPolarHBondContact O-CB 3.43Å; A118-A122 PolarHBondContact O-N 2.98Å; V119-A122 CarbonylContact O-C 3.57Å; V119-A122 WeakPolarHBondContact O-CB 3.27Å; V119-A122 PolarHBondContact O-N 3.11Å; V119-A122 VanDerWaalsContact O-N 3.09Å; C120-A122 PolarHBondContact O-N 3.38Å; A122-A124 VanDerWaalsContact C-N 3.35Å; A122-A125 PolarHBondContact O-N 3.08Å; A122-E126 WeakPolarHBondContact O-CB 3.22Å; A122-E126 PolarHBondContact O-N 3.47Å
123G98.6Very high98.7Very high0 Ų021.9 Ų21.90%013%0.129CC..Hα-helixtrans-61.6-40.4175.400000112.5V85 V119 C120 E126 K127V85-G123 WeakPolarHBondContact O-CA 3.32Å; V119-G123 PolarHBondContact O-N 3.38Å; C120-G123 PolarHBondContact O-N 3.47Å; G123-E126 PolarHBondContact O-N 3.39Å; G123-K127 PolarHBondContact O-N 2.83Å; G123-K127 VanDerWaalsContact O-N 3.09Å
124A98.8Very high98.7Very high4 Ų421.9 Ų21.93%0.03313%0.129CC..Hα-helixtrans-61-48173.800000111.9C120 K121 A122 E126 K127 G128 V129 L131 H134C120-A124 PolarHBondContact O-N 3.17Å; K121-A124 PolarHBondContact O-N 3.34Å; A122-A124 VanDerWaalsContact C-N 3.35Å; A124-E126 PolarHBondContact O-N 2.79Å; A124-K127 CarbonylContact O-C 3.32Å; A124-K127 PolarHBondContact O-N 3.03Å; A124-G128 PolarHBondContact O-N 2.89Å; A124-V129 CarbonylContact C-O 3.5Å; A124-V129 PolarHBondContact O-N 2.79Å; A124-V129 VanDerWaalsContact O-N 3.08Å; A124-L131 HydrophobicContact CB-CB 4.41Å; A124-L131 HydrophobicContact CB-CD1 4.17Å; A124-H134 HydrophobicContact CB-CB 3.5Å
125A98.5Very high98.7Very high32 Ų3221.9 Ų21.926%0.26413%0.129SC..Hα-helixtrans-68.8-32.4179.200000113.8F32 K121 A122 K127 G128F32-A125 HydrophobicContact CD1-CB 4.33Å; F32-A125 HydrophobicContact CE1-CB 3.21Å; F32-A125 HydrophobicContact CZ-CB 3.39Å; K121-A125 PolarHBondContact O-N 3.16Å; A122-A125 PolarHBondContact O-N 3.08Å; A125-K127 VanDerWaalsContact C-N 3.34Å; A125-G128 PolarHBondContact O-N 2.81Å
126E98.1Very high98.7Very high42 Ų4221.9 Ų21.920%0.19613%0.129CC..Hα-helixtrans-64.8-40.2172.7178.765.3174.500111.2M2 V85 V86 A122 G123 A124 G128M2-E126 WeakPolarHBondContact CB-OE1 3.04Å; M2-E126 WeakPolarHBondContact CB-OE2 3.48Å; M2-E126 WeakPolarHBondContact CE-OE2 3.47Å; M2-E126 WeakPolarHBondContact CG-OE1 3.47Å; M2-E126 WeakPolarHBondContact CG-OE2 3.11Å; M2-E126 PolarHBondContact N-OE1 3.13Å; V85-E126 HydrophobicContact CG2-CB 3.9Å; V85-E126 HydrophobicContact CG2-CG 4.28Å; V86-E126 HydrophobicContact CG1-CB 3.93Å; V86-E126 HydrophobicContact CG1-CG 3.72Å; A122-E126 WeakPolarHBondContact O-CB 3.22Å; A122-E126 PolarHBondContact O-N 3.47Å; G123-E126 PolarHBondContact O-N 3.39Å; A124-E126 PolarHBondContact O-N 2.79Å; E126-G128 VanDerWaalsContact C-N 3.26Å; E126-G128 PolarHBondContact O-N 2.94Å
127K98Very high98.7Very high90 Ų9025.1 Ų25.139%0.39115%0.146SC..Hα-helixtrans-74.4-13.8173-70.7-169.6-173.8177.40113.7V86 G123 A124 A125 V129 D137V86-K127 HydrophobicContact CG1-CG 3.94Å; G123-K127 PolarHBondContact O-N 2.83Å; G123-K127 VanDerWaalsContact O-N 3.09Å; A124-K127 CarbonylContact O-C 3.32Å; A124-K127 PolarHBondContact O-N 3.03Å; A125-K127 VanDerWaalsContact C-N 3.34Å; K127-V129 HydrophobicContact CB-CG2 3.94Å; K127-D137 IonicContact NZ-OD2 3.54Å
128G98.1Very high98.7Very high67 Ų6727.5 Ų27.569%0.69116%0.159SC*.THydrogen-bonded Turntrans6931-176.600000113.6A124 A125 E126A124-G128 PolarHBondContact O-N 2.89Å; A125-G128 PolarHBondContact O-N 2.81Å; E126-G128 VanDerWaalsContact C-N 3.26Å; E126-G128 PolarHBondContact O-N 2.94Å
129V98.7Very high98.6Very high45 Ų4528.8 Ų28.827%0.27317%0.169SC..SBendtrans-122.7157.2179.6-600000111.2A124 K127 R133 H134A124-V129 CarbonylContact C-O 3.5Å; A124-V129 PolarHBondContact O-N 2.79Å; A124-V129 VanDerWaalsContact O-N 3.08Å; K127-V129 HydrophobicContact CB-CG2 3.94Å; V129-R133 HydrophobicContact CB-CB 4.2Å; V129-R133 HydrophobicContact CB-CG 4.11Å; V129-R133 HydrophobicContact CG1-CG 4.43Å; V129-R133 HydrophobicContact CG2-CB 4.34Å; V129-R133 HydrophobicContact CG2-CG 4.39Å; V129-H134 HydrophobicContact CG2-CB 3.98Å
130P98.8Very high98.6Very high41 Ų4131.6 Ų31.627%0.26620%0.198SC..  trans-58.3155.4169.7-24.835.9000112.4Y132 R133 H134 E417P130-Y132 HydrophobicContact CB-CD1 3.77Å; P130-Y132 HydrophobicContact CB-CE1 3.3Å; P130-Y132 HydrophobicContact CB-CE2 4.42Å; P130-Y132 HydrophobicContact CG-CE1 4.01Å; P130-Y132 PolarHBondContact O-N 2.98Å; P130-R133 WeakPolarHBondContact O-CB 3.25Å; P130-R133 PolarHBondContact O-N 2.96Å; P130-R133 VanDerWaalsContact O-N 3.12Å; P130-H134 PolarHBondContact O-N 3.49Å; P130-E417 WeakPolarHBondContact CG-OE1 3.31Å
131L98.9Very high98.5Very high24 Ų2433.2 Ų33.213%0.12621%0.207CC..Hα-helixtrans-61.9-44.7-175.4175.164.2000112.3K121 A124 R133 H134 I135 F381 D384K121-L131 HydrophobicContact CG-CD1 4.35Å; K121-L131 HydrophobicContact CG-CD2 4.01Å; A124-L131 HydrophobicContact CB-CB 4.41Å; A124-L131 HydrophobicContact CB-CD1 4.17Å; L131-R133 PolarHBondContact O-N 2.97Å; L131-H134 WeakPolarHBondContact O-CB 3.49Å; L131-H134 PolarHBondContact O-N 2.88Å; L131-H134 VanDerWaalsContact O-N 3.12Å; L131-I135 HydrophobicContact CD1-CD1 3.98Å; L131-I135 HydrophobicContact CD1-CG1 4.1Å; L131-I135 HydrophobicContact CD2-CD1 4.49Å; L131-I135 HydrophobicContact CG-CD1 3.86Å; L131-I135 HydrophobicContact CG-CG1 4.39Å; L131-I135 WeakPolarHBondContact O-CG1 3.42Å; L131-I135 PolarHBondContact O-N 3.03Å; L131-F381 HydrophobicContact CD1-CE2 4.31Å; L131-F381 HydrophobicContact CD2-CD2 3.79Å; L131-F381 HydrophobicContact CD2-CE2 4.1Å; L131-D384 HydrophobicContact CB-CB 4.06Å; L131-D384 WeakPolarHBondContact CB-OD1 3.49Å; L131-D384 HydrophobicContact CD2-CB 3.75Å; L131-D384 HydrophobicContact CG-CB 3.74Å
132Y98.9Very high98.4Very high15 Ų1536.3 Ų36.36%0.05923%0.231CC..Hα-helixtrans-56.8-34.9175.964.4-96000112.9P130 A136 V144 D384 V387 G388 I414 E417 L418P130-Y132 HydrophobicContact CB-CD1 3.77Å; P130-Y132 HydrophobicContact CB-CE1 3.3Å; P130-Y132 HydrophobicContact CB-CE2 4.42Å; P130-Y132 HydrophobicContact CG-CE1 4.01Å; P130-Y132 PolarHBondContact O-N 2.98Å; Y132-A136 WeakPolarHBondContact O-CB 3.39Å; Y132-A136 PolarHBondContact O-N 2.87Å; Y132-V144 HydrophobicContact CD2-CG1 4.34Å; Y132-D384 WeakPolarHBondContact CA-O 3.25Å; Y132-D384 WeakPolarHBondContact CB-O 3.45Å; Y132-D384 WeakPolarHBondContact CD1-OD1 3.33Å; Y132-D384 PolarHBondContact N-OD1 3.5Å; Y132-V387 HydrophobicContact CD2-CG1 4.08Å; Y132-V387 HydrophobicContact CG-CG1 4.13Å; Y132-G388 VanDerWaalsContact O-CA 3.27Å; Y132-G388 WeakPolarHBondContact O-CA 3.17Å; Y132-I414 HydrophobicContact CD1-CB 4.39Å; Y132-I414 HydrophobicContact CD1-CD1 3.98Å; Y132-I414 HydrophobicContact CD1-CG1 3.75Å; Y132-I414 HydrophobicContact CD1-CG2 3.82Å; Y132-I414 HydrophobicContact CE1-CB 4.38Å; Y132-I414 HydrophobicContact CE1-CG1 4.01Å; Y132-I414 HydrophobicContact CE1-CG2 3.83Å; Y132-I414 HydrophobicContact CG-CG2 4.2Å; Y132-E417 WeakPolarHBondContact CE1-OE2 3.46Å; Y132-E417 VanDerWaalsContact OH-CD 3.27Å; Y132-E417 PolarHBondContact OH-OE2 2.99Å; Y132-L418 HydrophobicContact CE2-CD2 4.01Å; Y132-L418 HydrophobicContact CE2-CG 4.46Å
133R98.8Very high98.3Very high56 Ų5641.6 Ų41.621%0.21126%0.259CS..Hα-helixtrans-72.4-41.5178.1-175.261-95.4169.2-7.5111V129 P130 L131 I135 A136 D137 N141 P142V129-R133 HydrophobicContact CB-CB 4.2Å; V129-R133 HydrophobicContact CB-CG 4.11Å; V129-R133 HydrophobicContact CG1-CG 4.43Å; V129-R133 HydrophobicContact CG2-CB 4.34Å; V129-R133 HydrophobicContact CG2-CG 4.39Å; P130-R133 WeakPolarHBondContact O-CB 3.25Å; P130-R133 PolarHBondContact O-N 2.96Å; P130-R133 VanDerWaalsContact O-N 3.12Å; L131-R133 PolarHBondContact O-N 2.97Å; R133-I135 VanDerWaalsContact C-N 3.33Å; R133-I135 PolarHBondContact O-N 3.47Å; R133-A136 PolarHBondContact O-N 2.88Å; R133-D137 IonicContact CZ-OD1 2.8Å; R133-D137 VanDerWaalsContact CZ-OD1 3.29Å; R133-D137 IonicContact NE-OD1 2.84Å; R133-D137 PolarHBondContact NE-OD1 2.95Å; R133-D137 IonicContact NH2-OD1 2.54Å; R133-D137 PolarHBondContact NH2-OD1 3.24Å; R133-D137 VanDerWaalsContact O-CG 3.23Å; R133-D137 PolarHBondContact O-N 3.36Å; R133-N141 PolarHBondContact NH2-O 2.96Å; R133-P142 PolarHBondContact NH1-O 2.91Å
134H98.9Very high98.3Very high0 Ų042.5 Ų42.50%027%0.265CS..Hα-helixtrans-59.5-44.3173-177.464.3000112C120 A124 V129 P130 L131 D137 L138C120-H134 PolarHBondContact O-CD2 3.19Å; C120-H134 VanDerWaalsContact O-CD2 3.23Å; A124-H134 HydrophobicContact CB-CB 3.5Å; V129-H134 HydrophobicContact CG2-CB 3.98Å; P130-H134 PolarHBondContact O-N 3.49Å; L131-H134 WeakPolarHBondContact O-CB 3.49Å; L131-H134 PolarHBondContact O-N 2.88Å; L131-H134 VanDerWaalsContact O-N 3.12Å; H134-D137 WeakPolarHBondContact O-CB 3.48Å; H134-D137 PolarHBondContact O-N 2.83Å; H134-L138 WeakPolarHBondContact O-CG 3.48Å; H134-L138 PolarHBondContact O-N 3.09Å
135I98.9Very high98.3Very high0 Ų043 Ų430%027%0.266CS..Hα-helixtrans-63-44176.2-68.8172.8000110.8L131 R133 D137 L138 A139 L355 F381 D384 L385 L389L131-I135 HydrophobicContact CD1-CD1 3.98Å; L131-I135 HydrophobicContact CD1-CG1 4.1Å; L131-I135 HydrophobicContact CD2-CD1 4.49Å; L131-I135 HydrophobicContact CG-CD1 3.86Å; L131-I135 HydrophobicContact CG-CG1 4.39Å; L131-I135 WeakPolarHBondContact O-CG1 3.42Å; L131-I135 PolarHBondContact O-N 3.03Å; R133-I135 VanDerWaalsContact C-N 3.33Å; R133-I135 PolarHBondContact O-N 3.47Å; I135-D137 VanDerWaalsContact C-N 3.31Å; I135-D137 PolarHBondContact O-N 2.81Å; I135-L138 PolarHBondContact O-N 3.29Å; I135-A139 WeakPolarHBondContact O-CB 3.39Å; I135-A139 PolarHBondContact O-N 3.45Å; I135-L355 HydrophobicContact CG2-CD2 4.14Å; I135-F381 HydrophobicContact CD1-CE1 4.38Å; I135-F381 HydrophobicContact CD1-CE2 4.27Å; I135-F381 HydrophobicContact CD1-CZ 3.95Å; I135-D384 HydrophobicContact CD1-CB 4.24Å; I135-L385 HydrophobicContact CD1-CB 4.3Å; I135-L385 HydrophobicContact CD1-CD1 4.25Å; I135-L385 HydrophobicContact CG2-CD1 3.93Å; I135-L389 HydrophobicContact CG2-CG 4.49Å
136A98.8Very high98.3Very high0 Ų041.4 Ų41.40%025%0.254CS..Hα-helixtrans-59.6-40.6175.800000112.1Y132 R133 A139 G140 N141 V144 G388Y132-A136 WeakPolarHBondContact O-CB 3.39Å; Y132-A136 PolarHBondContact O-N 2.87Å; R133-A136 PolarHBondContact O-N 2.88Å; A136-A139 CarbonylContact O-C 3.59Å; A136-A139 PolarHBondContact O-N 3.22Å; A136-G140 PolarHBondContact O-N 2.92Å; A136-N141 HydrophobicContact CB-CB 4.22Å; A136-N141 PolarHBondContact O-N 3.35Å; A136-V144 HydrophobicContact CB-CG1 3.84Å; A136-G388 WeakPolarHBondContact CA-O 3.34Å; A136-G388 WeakPolarHBondContact CB-O 3.19Å
137D98.6Very high98.3Very high68 Ų6839.4 Ų39.436%0.36424%0.244SC..Hα-helixtrans-63-42.5174.6-61.6-11.1000112K127 R133 H134 I135 A139 G140K127-D137 IonicContact NZ-OD2 3.54Å; R133-D137 IonicContact CZ-OD1 2.8Å; R133-D137 VanDerWaalsContact CZ-OD1 3.29Å; R133-D137 IonicContact NE-OD1 2.84Å; R133-D137 PolarHBondContact NE-OD1 2.95Å; R133-D137 IonicContact NH2-OD1 2.54Å; R133-D137 PolarHBondContact NH2-OD1 3.24Å; R133-D137 VanDerWaalsContact O-CG 3.23Å; R133-D137 PolarHBondContact O-N 3.36Å; H134-D137 WeakPolarHBondContact O-CB 3.48Å; H134-D137 PolarHBondContact O-N 2.83Å; I135-D137 VanDerWaalsContact C-N 3.31Å; I135-D137 PolarHBondContact O-N 2.81Å; D137-A139 VanDerWaalsContact C-N 3.29Å; D137-A139 PolarHBondContact O-N 3.23Å; D137-G140 PolarHBondContact O-N 2.74Å
138L98.6Very high98.4Very high55 Ų5535.1 Ų35.129%0.28823%0.226SC..Hα-helixtrans-64.2-35.4176.6-69.2173.3000111.8Q88 H134 I135 G140 L355Q88-L138 HydrophobicContact CB-CD1 3.97Å; Q88-L138 HydrophobicContact CB-CD2 3.96Å; Q88-L138 HydrophobicContact CG-CD1 4.09Å; H134-L138 WeakPolarHBondContact O-CG 3.48Å; H134-L138 PolarHBondContact O-N 3.09Å; I135-L138 PolarHBondContact O-N 3.29Å; L138-G140 VanDerWaalsContact C-N 3.34Å; L138-L355 HydrophobicContact CB-CD1 3.67Å; L138-L355 HydrophobicContact CD1-CD1 4.38Å
139A98.1Very high98.4Very high27 Ų2732 Ų3222%0.22319%0.193CC..Hα-helixtrans-79.2-15.9177.500000113.5I135 A136 D137 L355 L389I135-A139 WeakPolarHBondContact O-CB 3.39Å; I135-A139 PolarHBondContact O-N 3.45Å; A136-A139 CarbonylContact O-C 3.59Å; A136-A139 PolarHBondContact O-N 3.22Å; D137-A139 VanDerWaalsContact C-N 3.29Å; D137-A139 PolarHBondContact O-N 3.23Å; A139-L355 HydrophobicContact CB-CD2 4.36Å; A139-L389 HydrophobicContact CB-CD2 3.94Å
140G97.9Very high98.4Very high59 Ų5929.8 Ų29.861%0.60818%0.18SC*.THydrogen-bonded Turntrans78.322.8-174.200000114.1A136 D137 L138A136-G140 PolarHBondContact O-N 2.92Å; D137-G140 PolarHBondContact O-N 2.74Å; L138-G140 VanDerWaalsContact C-N 3.34Å
141N97.8Very high98.4Very high34 Ų3427.9 Ų27.918%0.18217%0.167CC..  trans-91.3115.3-179.7-69.2-25.7000110.3R133 A136 G388 L389R133-N141 PolarHBondContact NH2-O 2.96Å; A136-N141 HydrophobicContact CB-CB 4.22Å; A136-N141 PolarHBondContact O-N 3.35Å; N141-G388 PolarHBondContact ND2-O 3.33Å; N141-L389 PolarHBondContact ND2-O 3.41Å
142P96.6Very high98.4Very high103 Ų10326.7 Ų26.767%0.66916%0.161SC*.SBendtrans-71-41.3-18027.1-32.8000111.9R133R133-P142 PolarHBondContact NH1-O 2.91Å
143D95.7Very high98.4Very high112 Ų11226 Ų2660%0.59916%0.158SC*.SBendtrans-99.9171.4177.3-62.4-58.6000111.2C390D143-C390 PolarHBondContact O-SG 3.3Å
144V98.3Very high98.3Very high19 Ų1923.3 Ų23.312%0.11515%0.148CC..  trans-131.7154.1174.9-65.80000111Y132 A136 V387 C390 L418Y132-V144 HydrophobicContact CD2-CG1 4.34Å; A136-V144 HydrophobicContact CB-CG1 3.84Å; V144-V387 HydrophobicContact CB-CG1 3.75Å; V144-V387 HydrophobicContact CG1-CG1 4.29Å; V144-V387 HydrophobicContact CG2-CG1 4.16Å; V144-C390 VanDerWaalsContact CA-SG 3.57Å; V144-L418 HydrophobicContact CG2-CD1 3.8Å; V144-L418 HydrophobicContact CG2-CD2 3.77Å; V144-L418 HydrophobicContact CG2-CG 4.48Å
145I98.7Very high98.1Very high13 Ų1323.3 Ų23.37%0.06715%0.148CC..  trans-133.9140.6178.7-137.7173000112.5V387 C390 R423 A425 P432I145-V387 WeakPolarHBondContact O-CA 3.45Å; I145-C390 HydrophobicContact CG2-CB 4.4Å; I145-R423 HydrophobicContact CD1-CB 4.39Å; I145-R423 HydrophobicContact CG1-CB 3.86Å; I145-R423 VanDerWaalsContact CG1-O 3.22Å; I145-R423 WeakPolarHBondContact CG1-O 3.46Å; I145-A425 HydrophobicContact CD1-CB 4.28Å; I145-P432 HydrophobicContact CD1-CB 3.42Å; I145-P432 VanDerWaalsContact CD1-CB 3.42Å; I145-P432 HydrophobicContact CG1-CB 4.48Å; I145-P432 HydrophobicContact CG2-CB 3.89Å; I145-P432 HydrophobicContact CG2-CG 4.05Å
146L98.9Very high97.8Very high0 Ų023.3 Ų23.30%015%0.148CC..BIsolated β-bridgetrans-79134.6170.5-83.4-67.3000109.7F179 V387 L411 E415 L418 A422 R423 F424 A425L146-F179 HydrophobicContact CB-CB 4.2Å; L146-F179 HydrophobicContact CD1-CB 4.21Å; L146-F179 HydrophobicContact CD1-CG 4.26Å; L146-F179 HydrophobicContact CG-CB 4.2Å; L146-V387 HydrophobicContact CD1-CG2 4.1Å; L146-L411 HydrophobicContact CD1-CB 4.43Å; L146-L411 HydrophobicContact CD1-CD2 4.13Å; L146-E415 HydrophobicContact CD1-CB 4.16Å; L146-E415 HydrophobicContact CG-CB 4.17Å; L146-L418 HydrophobicContact CD2-CD1 3.63Å; L146-A422 HydrophobicContact CD2-CB 4.46Å; L146-R423 WeakPolarHBondContact CB-O 3.36Å; L146-R423 PolarHBondContact N-O 2.65Å; L146-F424 HydrophobicContact CB-CD2 4.29Å; L146-A425 PolarHBondContact O-N 3.04Å
147P98.9Very high97.4Very high0 Ų023.4 Ų23.40%015%0.149CC..PPolyproline II helixtrans-82.4157.1-175.135.7-38.7000112.5P149 F179 V386 G392 I394 L411 F424P147-P149 WeakPolarHBondContact O-CD 3.16Å; P147-F179 HydrophobicContact CG-CE2 4.47Å; P147-F179 VanDerWaalsContact O-CD2 3.32Å; P147-F179 WeakPolarHBondContact O-CD2 3.32Å; P147-V386 HydrophobicContact CB-CG1 4.38Å; P147-V386 HydrophobicContact CB-CG2 3.71Å; P147-V386 HydrophobicContact CG-CG1 3.74Å; P147-V386 HydrophobicContact CG-CG2 4.03Å; P147-G392 CarbonylContact C-O 3.52Å; P147-G392 VanDerWaalsContact CA-C 3.47Å; P147-G392 WeakPolarHBondContact CA-O 3.41Å; P147-I394 HydrophobicContact CB-CB 4.27Å; P147-I394 HydrophobicContact CB-CG2 3.9Å; P147-I394 HydrophobicContact CG-CB 4.21Å; P147-I394 HydrophobicContact CG-CG2 3.55Å; P147-L411 HydrophobicContact CG-CD1 3.96Å; P147-L411 HydrophobicContact CG-CD2 4.06Å; P147-F424 WeakPolarHBondContact O-CE2 3.43Å
148V98.9Very high96.9Very high0 Ų022.9 Ų22.90%015%0.151CC..EExtended strand (participates in β ladder)trans-72.4125.4158.1178.10000108.9L172 V174 G392 Q393 I394 F424 A425 G426 F429V148-L172 HydrophobicContact CG1-CB 4.01Å; V148-L172 HydrophobicContact CG1-CD2 4.45Å; V148-L172 HydrophobicContact CG1-CG 4.49Å; V148-V174 HydrophobicContact CG1-CG1 4Å; V148-V174 HydrophobicContact CG2-CG1 4.41Å; V148-G392 PolarHBondContact N-O 2.89Å; V148-Q393 WeakPolarHBondContact O-CA 3.19Å; V148-I394 PolarHBondContact O-N 3.23Å; V148-I394 VanDerWaalsContact O-N 3.09Å; V148-F424 HydrophobicContact CB-CZ 4.42Å; V148-F424 HydrophobicContact CG2-CE1 4.33Å; V148-F424 HydrophobicContact CG2-CE2 4.13Å; V148-F424 HydrophobicContact CG2-CZ 3.74Å; V148-A425 HydrophobicContact CG2-CB 4.45Å; V148-G426 VanDerWaalsContact CG2-O 3.27Å; V148-G426 WeakPolarHBondContact CG2-O 3.3Å; V148-F429 HydrophobicContact CB-CB 3.99Å; V148-F429 HydrophobicContact CG2-CB 3.66Å
149P98.9Very high96.2Very high0 Ų020.9 Ų20.90%014%0.14CC..EExtended strand (participates in β ladder)trans-76.6130.4173.130.7-33.4000111.2P147 F151 P173 F179 A182 I394 Y408P147-P149 WeakPolarHBondContact O-CD 3.16Å; P149-F151 HydrophobicContact CB-CD1 4.42Å; P149-F151 HydrophobicContact CB-CD2 4.36Å; P149-F151 HydrophobicContact CB-CE1 3.82Å; P149-F151 HydrophobicContact CB-CE2 3.78Å; P149-F151 HydrophobicContact CB-CZ 3.46Å; P149-F151 VanDerWaalsContact CB-CZ 3.46Å; P149-F151 HydrophobicContact CG-CD2 4.34Å; P149-F151 HydrophobicContact CG-CE1 4.21Å; P149-F151 HydrophobicContact CG-CE2 3.43Å; P149-F151 VanDerWaalsContact CG-CE2 3.43Å; P149-F151 HydrophobicContact CG-CZ 3.34Å; P149-P173 HydrophobicContact CG-CG 4.02Å; P149-P173 VanDerWaalsContact O-CD 3.26Å; P149-P173 WeakPolarHBondContact O-CD 3.42Å; P149-F179 HydrophobicContact CB-CE2 4.21Å; P149-F179 HydrophobicContact CG-CE2 4.04Å; P149-A182 HydrophobicContact CG-CB 4.06Å; P149-I394 CarbonylContact C-O 3.07Å; P149-Y408 HydrophobicContact CB-CD1 4.26Å; P149-Y408 HydrophobicContact CB-CE1 3.61Å
150A98.9Very high95.5Very high0 Ų020.2 Ų20.20%014%0.135CC..EExtended strand (participates in β ladder)trans-97.399.3167.600000108.9M170 L172 I394 K395A150-M170 HydrophobicContact CB-CB 4.44Å; A150-M170 HydrophobicContact CB-SD 3.82Å; A150-L172 HydrophobicContact CB-CD1 4.01Å; A150-L172 HydrophobicContact CB-CD2 4.18Å; A150-L172 HydrophobicContact CB-CG 3.83Å; A150-I394 PolarHBondContact N-O 2.86Å; A150-K395 HydrophobicContact CB-CB 4.3Å
151F98.9Very high94.9Very high0 Ų021.8 Ų21.80%015%0.15CC..EExtended strand (participates in β ladder)trans-85.4114-177.1-59.1-72.7000110.4P149 V153 M170 I171 P173 M183 G397 P399 Y408P149-F151 HydrophobicContact CB-CD1 4.42Å; P149-F151 HydrophobicContact CB-CD2 4.36Å; P149-F151 HydrophobicContact CB-CE1 3.82Å; P149-F151 HydrophobicContact CB-CE2 3.78Å; P149-F151 HydrophobicContact CB-CZ 3.46Å; P149-F151 VanDerWaalsContact CB-CZ 3.46Å; P149-F151 HydrophobicContact CG-CD2 4.34Å; P149-F151 HydrophobicContact CG-CE1 4.21Å; P149-F151 HydrophobicContact CG-CE2 3.43Å; P149-F151 VanDerWaalsContact CG-CE2 3.43Å; P149-F151 HydrophobicContact CG-CZ 3.34Å; F151-V153 HydrophobicContact CB-CG1 4.02Å; F151-V153 WeakPolarHBondContact O-CG1 3.39Å; F151-V153 PolarHBondContact O-N 3.35Å; F151-M170 CarbonylContact O-C 3.54Å; F151-M170 WeakPolarHBondContact O-CA 3.5Å; F151-I171 HydrophobicContact CB-CG1 3.92Å; F151-I171 HydrophobicContact CD2-CG1 4.15Å; F151-I171 PolarHBondContact N-O 2.73Å; F151-I171 PolarHBondContact O-N 3.26Å; F151-P173 HydrophobicContact CE2-CG 4.07Å; F151-M183 HydrophobicContact CE1-CE 4Å; F151-M183 HydrophobicContact CE1-SD 3.63Å; F151-M183 HydrophobicContact CZ-CE 4.18Å; F151-M183 HydrophobicContact CZ-SD 3.48Å; F151-M183 WeakPolarHBondContact CZ-SD 3.22Å; F151-G397 WeakPolarHBondContact CA-O 3.17Å; F151-P399 HydrophobicContact CD1-CB 4.37Å; F151-P399 HydrophobicContact CD1-CG 4.38Å; F151-P399 HydrophobicContact CE1-CB 4.4Å; F151-Y408 HydrophobicContact CD1-CE1 4.08Å; F151-Y408 AromaticContact CD1-CE2 3.75Å; F151-Y408 HydrophobicContact CD1-CE2 3.75Å; F151-Y408 AromaticContact CD1-CZ 3.47Å; F151-Y408 VanDerWaalsContact CD1-CZ 3.47Å; F151-Y408 WeakPolarHBondContact CD1-OH 3.31Å; F151-Y408 HydrophobicContact CE1-CD1 4.03Å; F151-Y408 HydrophobicContact CE1-CD2 4.11Å; F151-Y408 AromaticContact CE1-CE1 3.61Å; F151-Y408 HydrophobicContact CE1-CE1 3.61Å; F151-Y408 AromaticContact CE1-CE2 3.7Å; F151-Y408 HydrophobicContact CE1-CE2 3.7Å; F151-Y408 HydrophobicContact CE1-CG 4.27Å; F151-Y408 AromaticContact CE1-CZ 3.43Å; F151-Y408 VanDerWaalsContact CE1-CZ 3.43Å; F151-Y408 HydrophobicContact CZ-CE1 4.43Å
152N98.1Very high94.5Very high0 Ų020.5 Ų20.50%014%0.144CC..EExtended strand (participates in β ladder)trans-68.9111.4170.4-178.312.2000110I154 N155 E168 M170 E211 A398N152-I154 PolarHBondContact OD1-O 3.36Å; N152-N155 PolarHBondContact ND2-OD1 3.16Å; N152-N155 PolarHBondContact OD1-OD1 3.26Å; N152-N155 VanDerWaalsContact OD1-OD1 3.11Å; N152-E168 WeakPolarHBondContact CB-OE2 3.38Å; N152-E168 VanDerWaalsContact CG-OE2 3.3Å; N152-E168 WeakPolarHBondContact ND2-CG 3.38Å; N152-E168 PolarHBondContact ND2-OE2 2.95Å; N152-E168 WeakPolarHBondContact OD1-CB 3.49Å; N152-M170 HydrophobicContact CB-CG 4.16Å; N152-E211 PolarHBondContact ND2-OE2 3.22Å; N152-A398 VanDerWaalsContact O-CA 3.27Å; N152-A398 WeakPolarHBondContact O-CA 3.4Å; N152-A398 WeakPolarHBondContact O-CB 3.37Å; N152-A398 PolarHBondContact O-N 2.9Å
153V98.5Very high94.3Very high0 Ų019.9 Ų19.90%013%0.131CC..EExtended strand (participates in β ladder)trans-118.4-18-170.9-67.20000114.2F151 F169 I171 Y190 L193 G213 F214 L228F151-V153 HydrophobicContact CB-CG1 4.02Å; F151-V153 WeakPolarHBondContact O-CG1 3.39Å; F151-V153 PolarHBondContact O-N 3.35Å; V153-F169 VanDerWaalsContact CG2-O 3.25Å; V153-F169 WeakPolarHBondContact CG2-O 3.32Å; V153-F169 PolarHBondContact N-O 3.34Å; V153-I171 HydrophobicContact CG1-CD1 4.01Å; V153-I171 HydrophobicContact CG1-CG1 3.91Å; V153-I171 HydrophobicContact CG2-CG1 4.32Å; V153-I171 HydrophobicContact CG2-CG2 4.04Å; V153-Y190 HydrophobicContact CB-CD2 4.17Å; V153-Y190 HydrophobicContact CG1-CD2 3.78Å; V153-L193 HydrophobicContact CB-CD2 3.78Å; V153-L193 HydrophobicContact CG2-CD2 3.91Å; V153-G213 WeakPolarHBondContact O-CA 3.5Å; V153-F214 WeakPolarHBondContact O-CD2 3.33Å; V153-F214 PolarHBondContact O-N 2.85Å; V153-L228 HydrophobicContact CG2-CD1 4.36Å; V153-L228 HydrophobicContact CG2-CD2 3.46Å; V153-L228 VanDerWaalsContact CG2-CD2 3.46Å
154I98.2Very high94.2Very high0 Ų014.6 Ų14.60%010%0.102CC..EExtended strand (participates in β ladder)trans-132.1128.7168.5-57.8176000108.4N152 L164 F169 L193 F214 P216 I218 A224 L227 L228N152-I154 PolarHBondContact OD1-O 3.36Å; I154-L164 HydrophobicContact CG2-CD2 4.08Å; I154-F169 HydrophobicContact CB-CB 4.17Å; I154-F169 HydrophobicContact CB-CD2 4.37Å; I154-F169 HydrophobicContact CG2-CD2 4.37Å; I154-F169 PolarHBondContact N-O 2.87Å; I154-F169 PolarHBondContact O-N 2.64Å; I154-L193 HydrophobicContact CD1-CD1 4.27Å; I154-L193 HydrophobicContact CD1-CD2 4.31Å; I154-L193 HydrophobicContact CG1-CD2 3.85Å; I154-F214 CarbonylContact C-O 3.59Å; I154-F214 WeakPolarHBondContact CA-O 3.39Å; I154-P216 HydrophobicContact CG2-CG 4.23Å; I154-I218 HydrophobicContact CG2-CD1 4.5Å; I154-A224 HydrophobicContact CD1-CB 4.2Å; I154-A224 HydrophobicContact CG2-CB 4.42Å; I154-L227 HydrophobicContact CD1-CB 4.13Å; I154-L227 HydrophobicContact CD1-CD1 4.34Å; I154-L228 HydrophobicContact CD1-CD2 3.69Å; I154-L228 HydrophobicContact CD1-CG 3.99Å; I154-L228 HydrophobicContact CG1-CD2 4.02Å
155N93.5Very high94.1Very high0 Ų013.7 Ų13.70%010%0.097CC..EExtended strand (participates in β ladder)trans-105.4138179.6-64.720.4000110.4N152 H159 A160 N162 Q167 G213 F214N152-N155 PolarHBondContact ND2-OD1 3.16Å; N152-N155 PolarHBondContact OD1-OD1 3.26Å; N152-N155 VanDerWaalsContact OD1-OD1 3.11Å; N155-H159 HydrophobicContact CB-CB 4.34Å; N155-A160 HydrophobicContact CB-CB 4.12Å; N155-A160 WeakPolarHBondContact O-CB 3.15Å; N155-N162 PolarHBondContact O-ND2 2.82Å; N155-Q167 WeakPolarHBondContact CA-O 3.36Å; N155-G213 VanDerWaalsContact OD1-CA 3.32Å; N155-G213 WeakPolarHBondContact OD1-CA 3.36Å; N155-F214 PolarHBondContact N-O 2.89Å
156G92.7Very high94Very high0 Ų013.1 Ų13.10%09%0.094CC..  trans-133.5-146.4167.700000110.3S158 H159 A160 L164 M166 Q167G156-S158 PolarHBondContact O-N 2.92Å; G156-H159 PolarHBondContact O-N 3.06Å; G156-H159 VanDerWaalsContact O-N 3.1Å; G156-A160 PolarHBondContact O-N 2.78Å; G156-L164 CarbonylContact C-O 3.48Å; G156-M166 CarbonylContact C-O 3.59Å; G156-M166 WeakPolarHBondContact CA-O 3.17Å; G156-Q167 PolarHBondContact N-O 3.07Å
157G91.6Very high93.8Very high2 Ų213.2 Ų13.22%0.0219%0.094CC..G310 helixtrans50.2-137.9176.700000113H159 L164 A165 M166 K263G157-H159 VanDerWaalsContact C-N 3.26Å; G157-H159 PolarHBondContact O-N 3.1Å; G157-L164 PolarHBondContact N-O 2.82Å; G157-A165 WeakPolarHBondContact CA-O 3.48Å; G157-A165 PolarHBondContact N-O 2.98Å; G157-M166 PolarHBondContact N-O 2.91Å; G157-K263 PolarHBondContact O-NZ 2.95Å
158S88.1Confident93.8Very high57 Ų5713.3 Ų13.340%0.39910%0.095SC..G310 helixtrans-77-8.2178.2-64.60000113.5G156 E251G156-S158 PolarHBondContact O-N 2.92Å; S158-E251 PolarHBondContact OG-OE2 2.97Å
159H83.1Confident93.8Very high12 Ų1213.3 Ų13.36%0.05610%0.095CC..G310 helixtrans-88.6-6.1179-69.4175.4000114N155 G156 G157 Q167 E168 E211N155-H159 HydrophobicContact CB-CB 4.34Å; G156-H159 PolarHBondContact O-N 3.06Å; G156-H159 VanDerWaalsContact O-N 3.1Å; G157-H159 VanDerWaalsContact C-N 3.26Å; G157-H159 PolarHBondContact O-N 3.1Å; H159-Q167 HydrophobicContact CB-CG 4.29Å; H159-Q167 WeakPolarHBondContact ND1-CG 3.37Å; H159-E168 IonicContact CE1-OE1 3.02Å; H159-E168 IonicContact ND1-OE1 3.73Å; H159-E211 IonicContact CE1-OE1 3.74Å; H159-E211 PolarHBondContact CE1-OE1 2.72Å; H159-E211 VanDerWaalsContact CE1-OE1 3.23Å; H159-E211 IonicContact ND1-OE1 2.84Å
160A84.1Confident93.8Very high14 Ų1413.4 Ų13.412%0.11610%0.095CC..  trans-148.8141.7-176.600000113.3N155 G156 N162 A215 K263N155-A160 HydrophobicContact CB-CB 4.12Å; N155-A160 WeakPolarHBondContact O-CB 3.15Å; G156-A160 PolarHBondContact O-N 2.78Å; A160-N162 PolarHBondContact O-N 2.95Å; A160-N162 VanDerWaalsContact O-N 3.12Å; A160-A215 HydrophobicContact CB-CB 3.74Å; A160-K263 PolarHBondContact O-NZ 2.75Å; A160-K263 VanDerWaalsContact O-NZ 3.15Å
161G83.9Confident93.8Very high91 Ų9113.4 Ų13.494%0.93810%0.095SC*.SBendtrans-76.114.9175.100000115.5
162N89.8Confident93.8Very high8 Ų813.5 Ų13.54%0.04310%0.096CC..SBendtrans-82.7-173.7173.160.816.7000111N155 A160 P216 K263N155-N162 PolarHBondContact O-ND2 2.82Å; A160-N162 PolarHBondContact O-N 2.95Å; A160-N162 VanDerWaalsContact O-N 3.12Å; N162-P216 VanDerWaalsContact CB-O 3.24Å; N162-P216 WeakPolarHBondContact CB-O 3.47Å; N162-P216 PolarHBondContact ND2-O 2.86Å; N162-K263 VanDerWaalsContact O-CD 3.3Å; N162-K263 WeakPolarHBondContact O-CD 3.33Å; N162-K263 WeakPolarHBondContact O-CE 3.12Å; N162-K263 PolarHBondContact O-NZ 2.66Å; N162-K263 PolarHBondContact OD1-NZ 2.69Å
163K92.1Very high93.8Very high90 Ų9013.5 Ų13.539%0.39110%0.096SC..SBendtrans-91.5-19.5176.9-65.6-163.1170.6-153.60114.9A165 I218 L219 K263 S264K163-A165 PolarHBondContact O-N 3.43Å; K163-I218 CarbonylContact C-O 3.58Å; K163-I218 PolarHBondContact N-O 2.86Å; K163-L219 HydrophobicContact CB-CB 4.01Å; K163-L219 HydrophobicContact CB-CD1 3.68Å; K163-L219 HydrophobicContact CB-CG 4.44Å; K163-L219 HydrophobicContact CD-CD1 4.29Å; K163-K263 WeakPolarHBondContact O-CE 3.43Å; K163-S264 PolarHBondContact NZ-OG 2.68Å; K163-S264 VanDerWaalsContact NZ-OG 3.16Å
164L94.5Very high93.8Very high0 Ų014.2 Ų14.20%010%0.1CC..  trans-49.5119.4-179-17264.4000111.5I154 G156 G157 F169 I218 N221 A224 K263I154-L164 HydrophobicContact CG2-CD2 4.08Å; G156-L164 CarbonylContact C-O 3.48Å; G157-L164 PolarHBondContact N-O 2.82Å; L164-F169 HydrophobicContact CD1-CE2 4.11Å; L164-F169 HydrophobicContact CD1-CZ 4.14Å; L164-F169 HydrophobicContact CD2-CD2 4.09Å; L164-F169 HydrophobicContact CD2-CE2 3.49Å; L164-F169 VanDerWaalsContact CD2-CE2 3.49Å; L164-F169 HydrophobicContact CD2-CZ 4.31Å; L164-F169 HydrophobicContact CG-CE2 3.99Å; L164-F169 HydrophobicContact CG-CZ 4.5Å; L164-I218 HydrophobicContact CB-CG1 4.23Å; L164-I218 WeakPolarHBondContact CB-O 3.4Å; L164-I218 HydrophobicContact CD1-CD1 4.25Å; L164-I218 HydrophobicContact CD1-CG1 4.2Å; L164-I218 HydrophobicContact CD2-CD1 3.95Å; L164-I218 HydrophobicContact CD2-CG1 4.08Å; L164-I218 HydrophobicContact CG-CG1 4.43Å; L164-I218 PolarHBondContact N-O 3.07Å; L164-N221 HydrophobicContact CD1-CB 4.32Å; L164-N221 WeakPolarHBondContact CD1-OD1 3.16Å; L164-A224 HydrophobicContact CD2-CB 4.35Å; L164-K263 WeakPolarHBondContact O-CE 3.3Å; L164-K263 PolarHBondContact O-NZ 3.17Å
165A95.4Very high93.9Very high1 Ų115.3 Ų15.31%0.00811%0.112CC..  trans-76.4-41.9-175.900000113.4G157 K163 F252 L260 F262G157-A165 WeakPolarHBondContact CA-O 3.48Å; G157-A165 PolarHBondContact N-O 2.98Å; K163-A165 PolarHBondContact O-N 3.43Å; A165-F252 HydrophobicContact CB-CD1 4.3Å; A165-F252 HydrophobicContact CB-CE1 4.38Å; A165-L260 HydrophobicContact CB-CB 4.37Å; A165-L260 HydrophobicContact CB-CD2 4.26Å; A165-L260 VanDerWaalsContact CB-O 3.23Å; A165-L260 WeakPolarHBondContact CB-O 3.38Å; A165-F262 HydrophobicContact CB-CD1 4.02Å; A165-F262 HydrophobicContact CB-CE1 4.09Å
166M97.2Very high94.1Very high0 Ų015.8 Ų15.80%012%0.115CC..SBendtrans-69.3137.2-180-63.2177.9-171.700110.6G156 G157 F169 N221 M245 V247 L260 L280 Y281 F284G156-M166 CarbonylContact C-O 3.59Å; G156-M166 WeakPolarHBondContact CA-O 3.17Å; G157-M166 PolarHBondContact N-O 2.91Å; M166-F169 HydrophobicContact CB-CE2 3.89Å; M166-F169 HydrophobicContact CB-CZ 3.81Å; M166-F169 HydrophobicContact SD-CZ 4.28Å; M166-N221 WeakPolarHBondContact CB-OD1 3.33Å; M166-N221 HydrophobicContact CE-CB 4.03Å; M166-N221 HydrophobicContact CG-CB 4.42Å; M166-N221 WeakPolarHBondContact CG-OD1 2.92Å; M166-N221 PolarHBondContact N-OD1 2.63Å; M166-N221 HydrophobicContact SD-CB 3.7Å; M166-N221 VanDerWaalsContact SD-CG 3.51Å; M166-M245 HydrophobicContact SD-CE 3.27Å; M166-M245 WeakPolarHBondContact SD-CE 3.37Å; M166-V247 HydrophobicContact CE-CG1 4.44Å; M166-V247 HydrophobicContact CG-CB 4.4Å; M166-V247 HydrophobicContact CG-CG1 3.84Å; M166-V247 HydrophobicContact CG-CG2 4.43Å; M166-V247 HydrophobicContact SD-CG1 4.47Å; M166-V247 HydrophobicContact SD-CG2 4.3Å; M166-L260 HydrophobicContact CE-CD2 4.46Å; M166-L280 HydrophobicContact CE-CD2 4.25Å; M166-Y281 HydrophobicContact CE-CD1 4.29Å; M166-Y281 HydrophobicContact CE-CE1 3.53Å; M166-Y281 HydrophobicContact SD-CE1 4.37Å; M166-F284 HydrophobicContact CE-CE2 3.84Å; M166-F284 HydrophobicContact SD-CE2 4.07Å
167Q95.6Very high94.4Very high2 Ų220 Ų201%0.00915%0.145CC..  trans-74.7-41.1-166.3-170.1162.8-99.500113.3N155 G156 H159 D246 V247 A248N155-Q167 WeakPolarHBondContact CA-O 3.36Å; G156-Q167 PolarHBondContact N-O 3.07Å; H159-Q167 HydrophobicContact CB-CG 4.29Å; H159-Q167 WeakPolarHBondContact ND1-CG 3.37Å; Q167-D246 PolarHBondContact N-O 3.16Å; Q167-D246 PolarHBondContact NE2-OD2 2.93Å; Q167-V247 PolarHBondContact N-O 3.41Å; Q167-A248 HydrophobicContact CB-CB 3.78Å; Q167-A248 HydrophobicContact CG-CB 4.4Å
168E97.9Very high94.7Very high3 Ų322.8 Ų22.81%0.01416%0.159CC..EExtended strand (participates in β ladder)trans-144.7141.9-173.3-46.8-176.3-154.800113.8N152 H159 M245 D246 K395N152-E168 WeakPolarHBondContact CB-OE2 3.38Å; N152-E168 VanDerWaalsContact CG-OE2 3.3Å; N152-E168 WeakPolarHBondContact ND2-CG 3.38Å; N152-E168 PolarHBondContact ND2-OE2 2.95Å; N152-E168 WeakPolarHBondContact OD1-CB 3.49Å; H159-E168 IonicContact CE1-OE1 3.02Å; H159-E168 IonicContact ND1-OE1 3.73Å; E168-M245 WeakPolarHBondContact O-CA 3.26Å; E168-D246 HydrophobicContact CB-CB 3.93Å; E168-D246 HydrophobicContact CG-CB 4.03Å; E168-D246 PolarHBondContact N-O 2.96Å; E168-D246 PolarHBondContact O-N 2.55Å; E168-K395 WeakPolarHBondContact OE1-CE 3.44Å; E168-K395 IonicContact OE1-NZ 3.56Å; E168-K395 PolarHBondContact OE1-NZ 2.82Å; E168-K395 WeakPolarHBondContact OE2-CE 3.42Å; E168-K395 IonicContact OE2-NZ 3.9Å; E168-K395 PolarHBondContact OE2-NZ 2.95Å; E168-K395 VanDerWaalsContact OE2-NZ 3.08Å
169F98.7Very high95.2Very high0 Ų020 Ų200%014%0.14CC..EExtended strand (participates in β ladder)trans-123.4115.6170.3-59.4-105.9000108.4V153 I154 L164 M166 N221 A224 L225 L228 M245V153-F169 VanDerWaalsContact CG2-O 3.25Å; V153-F169 WeakPolarHBondContact CG2-O 3.32Å; V153-F169 PolarHBondContact N-O 3.34Å; I154-F169 HydrophobicContact CB-CB 4.17Å; I154-F169 HydrophobicContact CB-CD2 4.37Å; I154-F169 HydrophobicContact CG2-CD2 4.37Å; I154-F169 PolarHBondContact N-O 2.87Å; I154-F169 PolarHBondContact O-N 2.64Å; L164-F169 HydrophobicContact CD1-CE2 4.11Å; L164-F169 HydrophobicContact CD1-CZ 4.14Å; L164-F169 HydrophobicContact CD2-CD2 4.09Å; L164-F169 HydrophobicContact CD2-CE2 3.49Å; L164-F169 VanDerWaalsContact CD2-CE2 3.49Å; L164-F169 HydrophobicContact CD2-CZ 4.31Å; L164-F169 HydrophobicContact CG-CE2 3.99Å; L164-F169 HydrophobicContact CG-CZ 4.5Å; M166-F169 HydrophobicContact CB-CE2 3.89Å; M166-F169 HydrophobicContact CB-CZ 3.81Å; M166-F169 HydrophobicContact SD-CZ 4.28Å; F169-N221 HydrophobicContact CZ-CB 4.06Å; F169-A224 HydrophobicContact CD1-CB 3.77Å; F169-A224 HydrophobicContact CD2-CB 3.95Å; F169-A224 HydrophobicContact CE1-CB 3.63Å; F169-A224 HydrophobicContact CE2-CB 3.88Å; F169-A224 HydrophobicContact CG-CB 3.93Å; F169-A224 HydrophobicContact CZ-CB 3.7Å; F169-L225 HydrophobicContact CD1-CD2 3.84Å; F169-L225 HydrophobicContact CD1-CG 4.15Å; F169-L225 HydrophobicContact CE1-CD2 4.17Å; F169-L225 HydrophobicContact CE1-CG 4.04Å; F169-L228 HydrophobicContact CB-CD1 3.77Å; F169-M245 HydrophobicContact CD1-CE 4.14Å; F169-M245 HydrophobicContact CD1-CG 4.25Å; F169-M245 HydrophobicContact CE1-CE 3.55Å; F169-M245 HydrophobicContact CE1-SD 4.41Å; F169-M245 HydrophobicContact CZ-CE 4.12Å
170M98.8Very high96Very high1 Ų126.4 Ų26.41%0.00517%0.168CC..EExtended strand (participates in β ladder)trans-108.9148-171-64.5173.6-88.500112.1A150 F151 N152 L172 I243 G244 D246 K395A150-M170 HydrophobicContact CB-CB 4.44Å; A150-M170 HydrophobicContact CB-SD 3.82Å; F151-M170 CarbonylContact O-C 3.54Å; F151-M170 WeakPolarHBondContact O-CA 3.5Å; N152-M170 HydrophobicContact CB-CG 4.16Å; M170-L172 HydrophobicContact CB-CD1 4.16Å; M170-I243 WeakPolarHBondContact O-CA 3.42Å; M170-G244 WeakPolarHBondContact CA-O 3.04Å; M170-G244 PolarHBondContact N-O 3.4Å; M170-G244 PolarHBondContact O-N 3.17Å; M170-D246 HydrophobicContact CE-CB 4.2Å; M170-K395 HydrophobicContact CE-CD 4.27Å; M170-K395 HydrophobicContact SD-CB 4.5Å; M170-K395 HydrophobicContact SD-CD 3.74Å; M170-K395 HydrophobicContact SD-CG 3.8Å
171I98.9Very high96.7Very high1 Ų126.7 Ų26.71%0.00517%0.167CC..EExtended strand (participates in β ladder)trans-109.2136.4167.359173000110.4F151 V153 V189 L228 I232 I241F151-I171 HydrophobicContact CB-CG1 3.92Å; F151-I171 HydrophobicContact CD2-CG1 4.15Å; F151-I171 PolarHBondContact N-O 2.73Å; F151-I171 PolarHBondContact O-N 3.26Å; V153-I171 HydrophobicContact CG1-CD1 4.01Å; V153-I171 HydrophobicContact CG1-CG1 3.91Å; V153-I171 HydrophobicContact CG2-CG1 4.32Å; V153-I171 HydrophobicContact CG2-CG2 4.04Å; I171-V189 HydrophobicContact CD1-CB 3.66Å; I171-V189 HydrophobicContact CD1-CG1 3.56Å; I171-L228 HydrophobicContact CG2-CD1 4.27Å; I171-L228 HydrophobicContact CG2-CD2 4.4Å; I171-I232 HydrophobicContact CG2-CD1 4.2Å; I171-I241 HydrophobicContact CB-CG2 3.78Å; I171-I241 HydrophobicContact CG2-CG2 4.08Å
172L98.9Very high97.4Very high1 Ų122.4 Ų22.41%0.00512%0.123CC..EExtended strand (participates in β ladder)trans-123.1109.4-179.6-7081.7000109.1V148 A150 M170 V174 I241 V242 F429V148-L172 HydrophobicContact CG1-CB 4.01Å; V148-L172 HydrophobicContact CG1-CD2 4.45Å; V148-L172 HydrophobicContact CG1-CG 4.49Å; A150-L172 HydrophobicContact CB-CD1 4.01Å; A150-L172 HydrophobicContact CB-CD2 4.18Å; A150-L172 HydrophobicContact CB-CG 3.83Å; M170-L172 HydrophobicContact CB-CD1 4.16Å; L172-V174 HydrophobicContact CB-CG1 4.15Å; L172-V174 PolarHBondContact O-N 3.42Å; L172-I241 WeakPolarHBondContact O-CA 3.14Å; L172-V242 HydrophobicContact CB-CG2 3.8Å; L172-V242 PolarHBondContact N-O 2.81Å; L172-V242 PolarHBondContact O-N 3.17Å; L172-F429 HydrophobicContact CD2-CE2 4.38Å
173P98.8Very high97.8Very high1 Ų122.9 Ų22.91%0.00613%0.125CC..  trans-79.561.618035.8-38.5000111.9P149 F151 G175 A176 A182 I185 K240 I241P149-P173 HydrophobicContact CG-CG 4.02Å; P149-P173 VanDerWaalsContact O-CD 3.26Å; P149-P173 WeakPolarHBondContact O-CD 3.42Å; F151-P173 HydrophobicContact CE2-CG 4.07Å; P173-G175 PolarHBondContact O-N 3.34Å; P173-G175 VanDerWaalsContact O-N 3.16Å; P173-A176 HydrophobicContact CB-CB 4.45Å; P173-A176 WeakPolarHBondContact O-CB 3.35Å; P173-A176 PolarHBondContact O-N 2.9Å; P173-A176 VanDerWaalsContact O-N 3.12Å; P173-A182 HydrophobicContact CB-CB 4.24Å; P173-A182 HydrophobicContact CG-CB 3.54Å; P173-A182 WeakPolarHBondContact CG-O 3.48Å; P173-I185 HydrophobicContact CB-CB 4.2Å; P173-I185 HydrophobicContact CB-CG2 3.79Å; P173-K240 CarbonylContact C-O 3.53Å; P173-K240 VanDerWaalsContact C-O 3.32Å; P173-K240 WeakPolarHBondContact CA-O 3.4Å; P173-I241 HydrophobicContact CB-CG1 4.32Å
174V98.8Very high98.2Very high15 Ų1523.5 Ų23.59%0.09113%0.125CC..THydrogen-bonded Turntrans-62.8-19.8-177.6-63.60000114.1V148 L172 K240 V242 G426 K427 F429V148-V174 HydrophobicContact CG1-CG1 4Å; V148-V174 HydrophobicContact CG2-CG1 4.41Å; L172-V174 HydrophobicContact CB-CG1 4.15Å; L172-V174 PolarHBondContact O-N 3.42Å; V174-K240 PolarHBondContact N-O 2.79Å; V174-K240 VanDerWaalsContact N-O 3.16Å; V174-V242 HydrophobicContact CB-CG2 4.33Å; V174-V242 HydrophobicContact CG1-CG2 3.61Å; V174-V242 HydrophobicContact CG2-CB 4.41Å; V174-V242 HydrophobicContact CG2-CG1 3.87Å; V174-V242 HydrophobicContact CG2-CG2 3.72Å; V174-G426 CarbonylContact O-C 3.52Å; V174-G426 VanDerWaalsContact O-C 3.3Å; V174-G426 WeakPolarHBondContact O-CA 3.37Å; V174-K427 PolarHBondContact O-N 3.05Å; V174-F429 HydrophobicContact CG1-CD1 3.91Å; V174-F429 HydrophobicContact CG1-CE1 4.18Å
175G98.7Very high98.4Very high23 Ų2323.5 Ų23.524%0.23713%0.125CC..THydrogen-bonded Turntrans-93.77.8176.900000114.9P173 K240P173-G175 PolarHBondContact O-N 3.34Å; P173-G175 VanDerWaalsContact O-N 3.16Å; G175-K240 PolarHBondContact N-O 3.39Å
176A98.8Very high98.5Very high9 Ų923.5 Ų23.57%0.07413%0.125CC..  trans-68.4152.2171.500000111.6P173 D181 A182 I185 F424P173-A176 HydrophobicContact CB-CB 4.45Å; P173-A176 WeakPolarHBondContact O-CB 3.35Å; P173-A176 PolarHBondContact O-N 2.9Å; P173-A176 VanDerWaalsContact O-N 3.12Å; A176-D181 HydrophobicContact CB-CB 4.21Å; A176-A182 HydrophobicContact CB-CB 3.69Å; A176-I185 HydrophobicContact CB-CD1 4Å; A176-F424 HydrophobicContact CB-CE1 3.92Å; A176-F424 HydrophobicContact CB-CZ 4.24Å; A176-F424 WeakPolarHBondContact O-CE1 3.32Å
177S98.4Very high98.6Very high90 Ų9024.8 Ų24.863%0.62914%0.135SC*.SBendtrans-78.2-27.1179.455.30000113.7D181S177-D181 PolarHBondContact N-OD2 2.9Å
178N98.8Very high98.8Very high59 Ų5927.8 Ų27.832%0.31615%0.149SC..SBendtrans-160.1176-177.158.739.5000109.5K180 D181 A182 E415N178-K180 PolarHBondContact OD1-N 3.16Å; N178-D181 PolarHBondContact O-N 3.47Å; N178-D181 WeakPolarHBondContact OD1-CB 3.19Å; N178-D181 PolarHBondContact OD1-N 2.87Å; N178-A182 PolarHBondContact O-N 2.82Å; N178-E415 WeakPolarHBondContact CB-OE1 3.22Å
179F98.9Very high98.8Very high0 Ų027.7 Ų27.70%015%0.149CC..Hα-helixtrans-66.2-39.5-176.7-175.3-93.7000112.2L146 P147 P149 D181 A182 M183 Y408 L411 L412 E415 F424L146-F179 HydrophobicContact CB-CB 4.2Å; L146-F179 HydrophobicContact CD1-CB 4.21Å; L146-F179 HydrophobicContact CD1-CG 4.26Å; L146-F179 HydrophobicContact CG-CB 4.2Å; P147-F179 HydrophobicContact CG-CE2 4.47Å; P147-F179 VanDerWaalsContact O-CD2 3.32Å; P147-F179 WeakPolarHBondContact O-CD2 3.32Å; P149-F179 HydrophobicContact CB-CE2 4.21Å; P149-F179 HydrophobicContact CG-CE2 4.04Å; F179-D181 VanDerWaalsContact C-N 3.34Å; F179-D181 PolarHBondContact O-N 3.12Å; F179-A182 WeakPolarHBondContact O-CB 3.48Å; F179-A182 PolarHBondContact O-N 3.44Å; F179-A182 VanDerWaalsContact O-N 3.17Å; F179-M183 HydrophobicContact CD1-CG 3.99Å; F179-M183 HydrophobicContact CE1-CG 3.36Å; F179-M183 HydrophobicContact CE1-SD 4Å; F179-M183 HydrophobicContact CZ-CG 3.69Å; F179-M183 HydrophobicContact CZ-SD 3.76Å; F179-M183 PolarHBondContact O-N 3.17Å; F179-Y408 WeakPolarHBondContact CE1-O 3.35Å; F179-Y408 HydrophobicContact CZ-CD1 4.08Å; F179-L411 HydrophobicContact CD1-CB 3.79Å; F179-L411 HydrophobicContact CD2-CB 4.41Å; F179-L411 HydrophobicContact CE1-CB 3.24Å; F179-L411 HydrophobicContact CE1-CD1 4.26Å; F179-L411 HydrophobicContact CE1-CG 4.37Å; F179-L411 HydrophobicContact CE2-CB 3.94Å; F179-L411 HydrophobicContact CE2-CD1 3.58Å; F179-L411 HydrophobicContact CE2-CG 4.33Å; F179-L411 HydrophobicContact CG-CB 4.35Å; F179-L411 HydrophobicContact CZ-CB 3.33Å; F179-L411 HydrophobicContact CZ-CD1 3.42Å; F179-L411 VanDerWaalsContact CZ-CD1 3.42Å; F179-L411 HydrophobicContact CZ-CG 4Å; F179-L412 HydrophobicContact CD1-CD2 3.9Å; F179-L412 HydrophobicContact CD1-CG 4.22Å; F179-L412 HydrophobicContact CE1-CD2 4.13Å; F179-L412 HydrophobicContact CE1-CG 4.04Å; F179-E415 WeakPolarHBondContact CA-OE1 3.44Å; F179-E415 VanDerWaalsContact CB-OE1 3.25Å; F179-E415 WeakPolarHBondContact CB-OE1 3.26Å; F179-E415 PolarHBondContact N-OE1 3.12Å; F179-F424 HydrophobicContact CB-CD2 4.18Å; F179-F424 HydrophobicContact CB-CE2 4.47Å; F179-F424 HydrophobicContact CD2-CE2 4.35Å
180K98.9Very high98.8Very high146 Ų14628.1 Ų28.164%0.63515%0.151SC*.Hα-helixtrans-58.1-43.1173.7-179.4175-179.6174.80113.1N178 M183 R184 L412 E415N178-K180 PolarHBondContact OD1-N 3.16Å; K180-M183 PolarHBondContact O-N 2.97Å; K180-R184 PolarHBondContact O-N 3.11Å; K180-R184 VanDerWaalsContact O-N 3.11Å; K180-L412 HydrophobicContact CB-CD2 3.83Å; K180-L412 HydrophobicContact CG-CD2 4.14Å; K180-E415 VanDerWaalsContact CB-OE2 3.22Å; K180-E415 WeakPolarHBondContact CB-OE2 3.41Å; K180-E415 PolarHBondContact N-OE2 2.77Å
181D98.9Very high98.8Very high20 Ų2033.2 Ų33.211%0.10717%0.174CC..Hα-helixtrans-67.9-38.9175.3-168.246.5000111.1A176 S177 N178 F179 M183 R184 I185 K240A176-D181 HydrophobicContact CB-CB 4.21Å; S177-D181 PolarHBondContact N-OD2 2.9Å; N178-D181 PolarHBondContact O-N 3.47Å; N178-D181 WeakPolarHBondContact OD1-CB 3.19Å; N178-D181 PolarHBondContact OD1-N 2.87Å; F179-D181 VanDerWaalsContact C-N 3.34Å; F179-D181 PolarHBondContact O-N 3.12Å; D181-M183 PolarHBondContact O-N 3.38Å; D181-R184 PolarHBondContact O-N 3.23Å; D181-R184 IonicContact OD1-CZ 2.64Å; D181-R184 IonicContact OD1-NE 2.66Å; D181-R184 PolarHBondContact OD1-NE 3.13Å; D181-R184 IonicContact OD1-NH2 3.85Å; D181-R184 PolarHBondContact OD1-NH2 3.48Å; D181-I185 WeakPolarHBondContact O-CB 3.45Å; D181-I185 VanDerWaalsContact O-CG1 3.26Å; D181-I185 WeakPolarHBondContact O-CG1 3.42Å; D181-I185 PolarHBondContact O-N 2.96Å; D181-I185 WeakPolarHBondContact OD2-CD1 3.32Å; D181-K240 IonicContact OD2-NZ 3.63Å
182A98.9Very high98.8Very high0 Ų035.2 Ų35.20%019%0.185CC..Hα-helixtrans-58.9-45.117400000112.2P149 P173 A176 N178 F179 I185 G186 F424P149-A182 HydrophobicContact CG-CB 4.06Å; P173-A182 HydrophobicContact CB-CB 4.24Å; P173-A182 HydrophobicContact CG-CB 3.54Å; P173-A182 WeakPolarHBondContact CG-O 3.48Å; A176-A182 HydrophobicContact CB-CB 3.69Å; N178-A182 PolarHBondContact O-N 2.82Å; F179-A182 WeakPolarHBondContact O-CB 3.48Å; F179-A182 PolarHBondContact O-N 3.44Å; F179-A182 VanDerWaalsContact O-N 3.17Å; A182-I185 PolarHBondContact O-N 3.44Å; A182-G186 PolarHBondContact O-N 2.92Å; A182-F424 HydrophobicContact CB-CE2 4.03Å; A182-F424 HydrophobicContact CB-CZ 3.74Å
183M98.9Very high98.8Very high18 Ų1835.2 Ų35.29%0.08919%0.185CC..Hα-helixtrans-60.5-45.9175.1-79-56.6-52.400112.4F151 F179 K180 D181 G186 A187 Y408 L412F151-M183 HydrophobicContact CE1-CE 4Å; F151-M183 HydrophobicContact CE1-SD 3.63Å; F151-M183 HydrophobicContact CZ-CE 4.18Å; F151-M183 HydrophobicContact CZ-SD 3.48Å; F151-M183 WeakPolarHBondContact CZ-SD 3.22Å; F179-M183 HydrophobicContact CD1-CG 3.99Å; F179-M183 HydrophobicContact CE1-CG 3.36Å; F179-M183 HydrophobicContact CE1-SD 4Å; F179-M183 HydrophobicContact CZ-CG 3.69Å; F179-M183 HydrophobicContact CZ-SD 3.76Å; F179-M183 PolarHBondContact O-N 3.17Å; K180-M183 PolarHBondContact O-N 2.97Å; D181-M183 PolarHBondContact O-N 3.38Å; M183-G186 PolarHBondContact O-N 3.24Å; M183-A187 WeakPolarHBondContact O-CB 3.49Å; M183-A187 PolarHBondContact O-N 3.03Å; M183-Y408 HydrophobicContact CE-CD1 4.48Å; M183-Y408 HydrophobicContact CE-CD2 4.24Å; M183-Y408 HydrophobicContact CE-CG 3.88Å; M183-Y408 VanDerWaalsContact SD-CB 3.59Å; M183-Y408 HydrophobicContact SD-CD1 3.67Å; M183-Y408 HydrophobicContact SD-CD2 4.44Å; M183-Y408 HydrophobicContact SD-CE1 4.46Å; M183-Y408 HydrophobicContact SD-CG 3.65Å; M183-L412 HydrophobicContact CB-CD2 4.4Å; M183-L412 HydrophobicContact CG-CD2 4.12Å; M183-L412 HydrophobicContact CG-CG 4.35Å
184R98.9Very high98.8Very high104 Ų10439.4 Ų39.439%0.39220%0.203SC..Hα-helixtrans-61.5-50.6178.2-177.4-17567.581.33.6111.3K180 D181 G186 A187 E188 Y237K180-R184 PolarHBondContact O-N 3.11Å; K180-R184 VanDerWaalsContact O-N 3.11Å; D181-R184 PolarHBondContact O-N 3.23Å; D181-R184 IonicContact OD1-CZ 2.64Å; D181-R184 IonicContact OD1-NE 2.66Å; D181-R184 PolarHBondContact OD1-NE 3.13Å; D181-R184 IonicContact OD1-NH2 3.85Å; D181-R184 PolarHBondContact OD1-NH2 3.48Å; R184-G186 PolarHBondContact O-N 3.05Å; R184-A187 PolarHBondContact O-N 3.4Å; R184-E188 WeakPolarHBondContact CG-OE1 3.43Å; R184-E188 IonicContact CZ-OE1 3.26Å; R184-E188 IonicContact NH1-OE1 2.73Å; R184-E188 PolarHBondContact NH1-OE1 2.93Å; R184-E188 IonicContact NH1-OE2 2.7Å; R184-E188 PolarHBondContact NH1-OE2 3.47Å; R184-E188 WeakPolarHBondContact O-CG 3.43Å; R184-E188 PolarHBondContact O-N 2.95Å; R184-Y237 PolarHBondContact NH1-OH 3.13Å
185I98.9Very high98.8Very high0 Ų043.1 Ų43.10%022%0.222CC..Hα-helixtrans-57-49.5178.3-72.4169.6000110.4P173 A176 D181 A182 A187 E188 V189 Y237 K240 I241P173-I185 HydrophobicContact CB-CB 4.2Å; P173-I185 HydrophobicContact CB-CG2 3.79Å; A176-I185 HydrophobicContact CB-CD1 4Å; D181-I185 WeakPolarHBondContact O-CB 3.45Å; D181-I185 VanDerWaalsContact O-CG1 3.26Å; D181-I185 WeakPolarHBondContact O-CG1 3.42Å; D181-I185 PolarHBondContact O-N 2.96Å; D181-I185 WeakPolarHBondContact OD2-CD1 3.32Å; A182-I185 PolarHBondContact O-N 3.44Å; I185-A187 PolarHBondContact O-N 2.79Å; I185-E188 PolarHBondContact O-N 3.09Å; I185-V189 WeakPolarHBondContact O-CG2 3.35Å; I185-V189 PolarHBondContact O-N 2.91Å; I185-Y237 HydrophobicContact CB-CD2 4.5Å; I185-Y237 HydrophobicContact CB-CE2 4.45Å; I185-Y237 HydrophobicContact CD1-CD1 4.38Å; I185-Y237 HydrophobicContact CD1-CE1 4.31Å; I185-Y237 HydrophobicContact CG1-CD1 4.12Å; I185-Y237 HydrophobicContact CG1-CD2 4.5Å; I185-Y237 HydrophobicContact CG1-CE1 3.82Å; I185-Y237 HydrophobicContact CG1-CE2 4.23Å; I185-Y237 HydrophobicContact CG1-CG 4.46Å; I185-Y237 HydrophobicContact CG2-CD1 4.29Å; I185-Y237 HydrophobicContact CG2-CD2 3.86Å; I185-Y237 HydrophobicContact CG2-CE2 4.29Å; I185-Y237 HydrophobicContact CG2-CG 3.87Å; I185-K240 HydrophobicContact CD1-CD 3.7Å; I185-I241 HydrophobicContact CG2-CD1 3.56Å; I185-I241 HydrophobicContact CG2-CG1 3.76Å
186G98.8Very high98.8Very high0 Ų042.6 Ų42.60%022%0.215CC..Hα-helixtrans-59.5-44.9178.700000113.2A182 M183 R184 V189 Y190A182-G186 PolarHBondContact O-N 2.92Å; M183-G186 PolarHBondContact O-N 3.24Å; R184-G186 PolarHBondContact O-N 3.05Å; G186-V189 PolarHBondContact O-N 3.28Å; G186-Y190 WeakPolarHBondContact O-CB 3.36Å; G186-Y190 PolarHBondContact O-N 2.87Å
187A98.9Very high98.7Very high27 Ų2742.2 Ų42.222%0.22321%0.211CC..Hα-helixtrans-65.4-41.7178.100000112.8M183 R184 I185 Y190 H191 P399M183-A187 WeakPolarHBondContact O-CB 3.49Å; M183-A187 PolarHBondContact O-N 3.03Å; R184-A187 PolarHBondContact O-N 3.4Å; I185-A187 PolarHBondContact O-N 2.79Å; A187-Y190 PolarHBondContact O-N 3.49Å; A187-H191 PolarHBondContact O-N 2.7Å; A187-H191 PolarHBondContact O-ND1 2.78Å; A187-P399 HydrophobicContact CB-CB 4.33Å
188E98.9Very high98.7Very high66 Ų6643.4 Ų43.431%0.30821%0.205SC..Hα-helixtrans-63.9-40.4176.9-74175-159.800111.8R184 I185 N192 Y237R184-E188 WeakPolarHBondContact CG-OE1 3.43Å; R184-E188 IonicContact CZ-OE1 3.26Å; R184-E188 IonicContact NH1-OE1 2.73Å; R184-E188 PolarHBondContact NH1-OE1 2.93Å; R184-E188 IonicContact NH1-OE2 2.7Å; R184-E188 PolarHBondContact NH1-OE2 3.47Å; R184-E188 WeakPolarHBondContact O-CG 3.43Å; R184-E188 PolarHBondContact O-N 2.95Å; I185-E188 PolarHBondContact O-N 3.09Å; E188-N192 PolarHBondContact O-N 2.93Å; E188-N192 PolarHBondContact O-ND2 3.3Å; E188-Y237 HydrophobicContact CB-CE2 4.1Å; E188-Y237 WeakPolarHBondContact OE2-CE2 3.41Å; E188-Y237 VanDerWaalsContact OE2-CZ 3.25Å; E188-Y237 PolarHBondContact OE2-OH 2.75Å
189V98.9Very high98.6Very high1 Ų147.7 Ų47.71%0.00622%0.223CC..Hα-helixtrans-67-42.7173.8176.90000111.7I171 I185 G186 H191 N192 L193 A231 I232 A235 Y237 I241I171-V189 HydrophobicContact CD1-CB 3.66Å; I171-V189 HydrophobicContact CD1-CG1 3.56Å; I185-V189 WeakPolarHBondContact O-CG2 3.35Å; I185-V189 PolarHBondContact O-N 2.91Å; G186-V189 PolarHBondContact O-N 3.28Å; V189-H191 VanDerWaalsContact C-N 3.33Å; V189-H191 PolarHBondContact O-N 2.93Å; V189-N192 PolarHBondContact O-N 2.7Å; V189-L193 WeakPolarHBondContact O-CB 3.33Å; V189-L193 PolarHBondContact O-N 2.89Å; V189-A231 HydrophobicContact CG1-CB 4.27Å; V189-I232 HydrophobicContact CG1-CG1 3.83Å; V189-A235 HydrophobicContact CG2-CB 3.69Å; V189-Y237 HydrophobicContact CG2-CD2 3.87Å; V189-I241 HydrophobicContact CB-CD1 4.17Å; V189-I241 HydrophobicContact CG1-CD1 4.45Å; V189-I241 HydrophobicContact CG2-CD1 3.22Å
190Y98.9Very high98.6Very high9 Ų953.2 Ų53.24%0.03525%0.247CC..Hα-helixtrans-58.8-42.9176.3177.5-100.2000112.1V153 G186 A187 L193 K194 V208 G212 F214 A398 P399 C400V153-Y190 HydrophobicContact CB-CD2 4.17Å; V153-Y190 HydrophobicContact CG1-CD2 3.78Å; G186-Y190 WeakPolarHBondContact O-CB 3.36Å; G186-Y190 PolarHBondContact O-N 2.87Å; A187-Y190 PolarHBondContact O-N 3.49Å; Y190-L193 WeakPolarHBondContact O-CB 3.48Å; Y190-L193 PolarHBondContact O-N 2.71Å; Y190-K194 PolarHBondContact O-N 2.88Å; Y190-V208 VanDerWaalsContact OH-CG1 3.32Å; Y190-V208 WeakPolarHBondContact OH-CG1 3.26Å; Y190-G212 WeakPolarHBondContact CE2-O 3.44Å; Y190-G212 PolarHBondContact OH-O 2.94Å; Y190-F214 HydrophobicContact CD1-CZ 4.36Å; Y190-F214 HydrophobicContact CD2-CD2 4.46Å; Y190-F214 AromaticContact CD2-CE2 3.69Å; Y190-F214 HydrophobicContact CD2-CE2 3.69Å; Y190-F214 HydrophobicContact CD2-CZ 4.14Å; Y190-F214 HydrophobicContact CE1-CE2 4.28Å; Y190-F214 AromaticContact CE1-CZ 3.75Å; Y190-F214 HydrophobicContact CE1-CZ 3.75Å; Y190-F214 HydrophobicContact CE2-CD2 4.02Å; Y190-F214 HydrophobicContact CE2-CE1 4.34Å; Y190-F214 AromaticContact CE2-CE2 3.37Å; Y190-F214 HydrophobicContact CE2-CE2 3.37Å; Y190-F214 AromaticContact CE2-CZ 3.54Å; Y190-F214 HydrophobicContact CE2-CZ 3.54Å; Y190-F214 HydrophobicContact CG-CE2 4.3Å; Y190-F214 AromaticContact CZ-CE1 3.95Å; Y190-F214 AromaticContact CZ-CE2 3.7Å; Y190-F214 AromaticContact CZ-CZ 3.3Å; Y190-F214 WeakPolarHBondContact OH-CZ 3.42Å; Y190-A398 HydrophobicContact CD2-CB 4.49Å; Y190-A398 HydrophobicContact CE2-CB 4.02Å; Y190-P399 HydrophobicContact CD1-CG 4.08Å; Y190-P399 HydrophobicContact CD2-CG 4.3Å; Y190-P399 HydrophobicContact CG-CG 3.75Å; Y190-C400 HydrophobicContact CE1-CB 3.95Å; Y190-C400 WeakPolarHBondContact OH-CB 3.49Å
191H98.8Very high98.4Very high107 Ų10749.2 Ų49.250%0.49523%0.229SC..Hα-helixtrans-68.3-37.2175.6-66.4151.4000113.2A187 V189 K194 N195A187-H191 PolarHBondContact O-N 2.7Å; A187-H191 PolarHBondContact O-ND1 2.78Å; V189-H191 VanDerWaalsContact C-N 3.33Å; V189-H191 PolarHBondContact O-N 2.93Å; H191-K194 WeakPolarHBondContact O-CB 3.32Å; H191-K194 PolarHBondContact O-N 2.84Å; H191-N195 PolarHBondContact O-N 3.46Å; H191-N195 PolarHBondContact O-ND2 3.03Å
192N98.8Very high98.3Very high44 Ų4449.8 Ų49.824%0.23524%0.239CC..Hα-helixtrans-64.7-41.9172.6-86.3-79.5000111.7E188 V189 K194 N195 V196 A235E188-N192 PolarHBondContact O-N 2.93Å; E188-N192 PolarHBondContact O-ND2 3.3Å; V189-N192 PolarHBondContact O-N 2.7Å; N192-K194 VanDerWaalsContact C-N 3.32Å; N192-K194 PolarHBondContact O-N 2.93Å; N192-N195 WeakPolarHBondContact O-CB 3.37Å; N192-N195 PolarHBondContact O-N 2.87Å; N192-N195 VanDerWaalsContact O-N 3.11Å; N192-V196 WeakPolarHBondContact O-CG2 3.34Å; N192-V196 PolarHBondContact O-N 2.8Å; N192-A235 HydrophobicContact CB-CB 4.38Å
193L98.8Very high98.2Very high0 Ų056.6 Ų56.60%027%0.269CS..Hα-helixtrans-59.7-43175.4179.863000111.2V153 I154 V189 Y190 N195 V196 I197 F214 L227 L228 A231V153-L193 HydrophobicContact CB-CD2 3.78Å; V153-L193 HydrophobicContact CG2-CD2 3.91Å; I154-L193 HydrophobicContact CD1-CD1 4.27Å; I154-L193 HydrophobicContact CD1-CD2 4.31Å; I154-L193 HydrophobicContact CG1-CD2 3.85Å; V189-L193 WeakPolarHBondContact O-CB 3.33Å; V189-L193 PolarHBondContact O-N 2.89Å; Y190-L193 WeakPolarHBondContact O-CB 3.48Å; Y190-L193 PolarHBondContact O-N 2.71Å; L193-N195 VanDerWaalsContact C-N 3.26Å; L193-N195 PolarHBondContact O-N 2.89Å; L193-V196 PolarHBondContact O-N 2.79Å; L193-I197 HydrophobicContact CD1-CD1 3.89Å; L193-I197 HydrophobicContact CD1-CG1 4.1Å; L193-I197 HydrophobicContact CD2-CD1 4.42Å; L193-I197 HydrophobicContact CG-CD1 3.8Å; L193-I197 HydrophobicContact CG-CG1 4.38Å; L193-I197 WeakPolarHBondContact O-CB 3.37Å; L193-I197 WeakPolarHBondContact O-CG1 3.35Å; L193-I197 PolarHBondContact O-N 3.03Å; L193-F214 HydrophobicContact CB-CE2 4.38Å; L193-F214 HydrophobicContact CD2-CD2 3.89Å; L193-F214 HydrophobicContact CD2-CE2 4.25Å; L193-F214 HydrophobicContact CG-CD2 3.99Å; L193-F214 HydrophobicContact CG-CE2 4.22Å; L193-L227 HydrophobicContact CD1-CB 4.05Å; L193-L228 HydrophobicContact CD1-CD2 4.13Å; L193-L228 HydrophobicContact CD2-CD2 3.66Å; L193-A231 HydrophobicContact CB-CB 3.67Å; L193-A231 HydrophobicContact CD1-CB 3.91Å; L193-A231 HydrophobicContact CG-CB 4.39Å
194K98.7Very high98Very high89 Ų8961.2 Ų61.239%0.38729%0.294SS..Hα-helixtrans-52.7-45.9173.3-168174.1178.7170.60111.8Y190 H191 N192 K198 T206 F214Y190-K194 PolarHBondContact O-N 2.88Å; H191-K194 WeakPolarHBondContact O-CB 3.32Å; H191-K194 PolarHBondContact O-N 2.84Å; N192-K194 VanDerWaalsContact C-N 3.32Å; N192-K194 PolarHBondContact O-N 2.93Å; K194-K198 VanDerWaalsContact O-CB 3.27Å; K194-K198 WeakPolarHBondContact O-CB 3.28Å; K194-K198 PolarHBondContact O-N 3.3Å; K194-T206 HydrophobicContact CG-CG2 3.85Å; K194-T206 WeakPolarHBondContact O-CG2 3.33Å; K194-F214 HydrophobicContact CB-CE1 4.06Å; K194-F214 HydrophobicContact CB-CE2 3.88Å; K194-F214 HydrophobicContact CB-CZ 3.39Å; K194-F214 HydrophobicContact CD-CE1 4.11Å; K194-F214 HydrophobicContact CD-CZ 4.01Å; K194-F214 HydrophobicContact CG-CE1 3.76Å; K194-F214 HydrophobicContact CG-CE2 4.49Å; K194-F214 HydrophobicContact CG-CZ 3.62Å
195N98.3Very high97.8Very high94 Ų9456.8 Ų56.850%0.50328%0.28SS..Hα-helixtrans-68.5-43-179.3-67.6-26.7000111.8H191 N192 L193 I197 K198 E199H191-N195 PolarHBondContact O-N 3.46Å; H191-N195 PolarHBondContact O-ND2 3.03Å; N192-N195 WeakPolarHBondContact O-CB 3.37Å; N192-N195 PolarHBondContact O-N 2.87Å; N192-N195 VanDerWaalsContact O-N 3.11Å; L193-N195 VanDerWaalsContact C-N 3.26Å; L193-N195 PolarHBondContact O-N 2.89Å; N195-I197 PolarHBondContact O-N 2.82Å; N195-K198 PolarHBondContact O-N 3.04Å; N195-E199 VanDerWaalsContact O-CB 3.31Å; N195-E199 WeakPolarHBondContact O-CB 3.29Å; N195-E199 PolarHBondContact O-N 2.89Å
196V98.1Very high97.7Very high12 Ų1257.9 Ų57.97%0.07329%0.286CS..Hα-helixtrans-59.4-46175.3172.20000111.1N192 L193 E199 K200 L227 K234N192-V196 WeakPolarHBondContact O-CG2 3.34Å; N192-V196 PolarHBondContact O-N 2.8Å; L193-V196 PolarHBondContact O-N 2.79Å; V196-E199 PolarHBondContact O-N 3.5Å; V196-K200 WeakPolarHBondContact O-CB 3.46Å; V196-K200 PolarHBondContact O-N 3.44Å; V196-K200 VanDerWaalsContact O-N 3.09Å; V196-L227 HydrophobicContact CG1-CD2 3.75Å; V196-K234 HydrophobicContact CG2-CD 3.7Å
197I98.1Very high97.5Very high0 Ų063 Ų630%031%0.314CS..Hα-helixtrans-64.8-45178-71.5173.1000110.6L193 N195 E199 K200 Y201 A205 T206 F214 P216 L227L193-I197 HydrophobicContact CD1-CD1 3.89Å; L193-I197 HydrophobicContact CD1-CG1 4.1Å; L193-I197 HydrophobicContact CD2-CD1 4.42Å; L193-I197 HydrophobicContact CG-CD1 3.8Å; L193-I197 HydrophobicContact CG-CG1 4.38Å; L193-I197 WeakPolarHBondContact O-CB 3.37Å; L193-I197 WeakPolarHBondContact O-CG1 3.35Å; L193-I197 PolarHBondContact O-N 3.03Å; N195-I197 PolarHBondContact O-N 2.82Å; I197-E199 VanDerWaalsContact C-N 3.31Å; I197-E199 PolarHBondContact O-N 3.25Å; I197-K200 PolarHBondContact O-N 3.1Å; I197-Y201 HydrophobicContact CG2-CD2 4.15Å; I197-Y201 PolarHBondContact O-N 3.35Å; I197-A205 HydrophobicContact CG2-CB 3.68Å; I197-A205 WeakPolarHBondContact CG2-O 3.18Å; I197-T206 HydrophobicContact CB-CG2 4.48Å; I197-T206 HydrophobicContact CG2-CG2 4.09Å; I197-F214 HydrophobicContact CD1-CB 3.53Å; I197-F214 HydrophobicContact CD1-CD2 3.69Å; I197-F214 HydrophobicContact CD1-CG 3.77Å; I197-P216 HydrophobicContact CD1-CG 4.23Å; I197-P216 HydrophobicContact CG2-CB 4.15Å; I197-L227 HydrophobicContact CG1-CD1 4.44Å
198K97.9Very high97.3Very high115 Ų11564.2 Ų64.250%0.532%0.318SS..Hα-helixtrans-59.1-42.9178.1-174.9174.4176.9-173.90112.3K194 N195 G202 T206K194-K198 VanDerWaalsContact O-CB 3.27Å; K194-K198 WeakPolarHBondContact O-CB 3.28Å; K194-K198 PolarHBondContact O-N 3.3Å; N195-K198 PolarHBondContact O-N 3.04Å; K198-G202 CarbonylContact O-C 3.35Å; K198-G202 WeakPolarHBondContact O-CA 3.39Å; K198-G202 PolarHBondContact O-N 2.79Å; K198-T206 HydrophobicContact CB-CG2 3.71Å; K198-T206 HydrophobicContact CG-CG2 4.45Å
199E97.5Very high96.8Very high150 Ų15061.7 Ų61.770%0.70131%0.31SS*.Hα-helixtrans-65.2-42.4179.8-174.7177.9-175.100111.2N195 V196 I197 K234N195-E199 VanDerWaalsContact O-CB 3.31Å; N195-E199 WeakPolarHBondContact O-CB 3.29Å; N195-E199 PolarHBondContact O-N 2.89Å; V196-E199 PolarHBondContact O-N 3.5Å; I197-E199 VanDerWaalsContact C-N 3.31Å; I197-E199 PolarHBondContact O-N 3.25Å; E199-K234 IonicContact OE2-NZ 2.7Å; E199-K234 PolarHBondContact OE2-NZ 2.82Å
200K97.3Very high96.3Very high116 Ų11664.1 Ų64.150%0.50432%0.323SS..Hα-helixtrans-86-40-174.7-170.2174.3176.1-160.90114.5V196 I197 E223 L227V196-K200 WeakPolarHBondContact O-CB 3.46Å; V196-K200 PolarHBondContact O-N 3.44Å; V196-K200 VanDerWaalsContact O-N 3.09Å; I197-K200 PolarHBondContact O-N 3.1Å; K200-E223 IonicContact NZ-OE1 3.4Å; K200-E223 PolarHBondContact NZ-OE1 3.46Å; K200-L227 HydrophobicContact CD-CD2 4.27Å
201Y96.2Very high96.1Very high62 Ų6263.9 Ų63.924%0.24332%0.322CS..Hα-helixtrans-118.62.7-171.5-51.9-75.7000113.7I197 P216 I218 E223 L227I197-Y201 HydrophobicContact CG2-CD2 4.15Å; I197-Y201 PolarHBondContact O-N 3.35Å; Y201-P216 HydrophobicContact CD2-CB 3.95Å; Y201-P216 HydrophobicContact CE2-CB 4.17Å; Y201-P216 HydrophobicContact CG-CB 4.39Å; Y201-I218 HydrophobicContact CE1-CG2 3.8Å; Y201-I218 HydrophobicContact CE2-CG2 4.2Å; Y201-I218 VanDerWaalsContact OH-CG2 3.32Å; Y201-I218 WeakPolarHBondContact OH-CG2 3.29Å; Y201-E223 WeakPolarHBondContact OH-CG 3.35Å; Y201-E223 PolarHBondContact OH-OE1 3.31Å; Y201-L227 HydrophobicContact CE2-CD1 3.74Å; Y201-L227 HydrophobicContact CE2-CD2 3.88Å; Y201-L227 HydrophobicContact CE2-CG 4.42Å
202G96.9Very high96Very high32 Ų3258.8 Ų58.833%0.3330%0.298SS..  trans84.7170.5-17900000114K198 D204 A205K198-G202 CarbonylContact O-C 3.35Å; K198-G202 WeakPolarHBondContact O-CA 3.39Å; K198-G202 PolarHBondContact O-N 2.79Å; G202-D204 VanDerWaalsContact C-N 3.3Å; G202-D204 PolarHBondContact O-N 2.94Å; G202-A205 PolarHBondContact O-N 3.11Å
203K95.7Very high95.9Very high142 Ų14256.7 Ų56.762%0.61729%0.287SS*.G310 helixtrans-61.8-34.2-173.568.7179-175.8174.90113.5A205 T206K203-A205 PolarHBondContact O-N 2.66Å; K203-T206 WeakPolarHBondContact O-CB 3.4Å; K203-T206 PolarHBondContact O-N 2.88Å; K203-T206 PolarHBondContact O-OG1 3.03Å
204D94.1Very high95.9Very high115 Ų11556.7 Ų56.762%0.61529%0.287SS*.G310 helixtrans-71.5-24.6-173.4-58.7-29.1000111.4G202 T206 N207G202-D204 VanDerWaalsContact C-N 3.3Å; G202-D204 PolarHBondContact O-N 2.94Å; D204-T206 PolarHBondContact O-N 3.39Å; D204-N207 PolarHBondContact O-N 3.4Å; D204-N207 PolarHBondContact O-ND2 3.5Å
205A95.2Very high95.7Very high12 Ų1253.9 Ų53.910%0.09928%0.281CS..G310 helixtrans-70-7.917200000113.7I197 G202 K203 P216I197-A205 HydrophobicContact CG2-CB 3.68Å; I197-A205 WeakPolarHBondContact CG2-O 3.18Å; G202-A205 PolarHBondContact O-N 3.11Å; K203-A205 PolarHBondContact O-N 2.66Å; A205-P216 HydrophobicContact CB-CB 4.39Å
206T96.3Very high95.5Very high22 Ų2249.4 Ų49.414%0.13526%0.257CS..G310 helixtrans-94.16.6175.869.30000114.1K194 I197 K198 K203 D204 F214K194-T206 HydrophobicContact CG-CG2 3.85Å; K194-T206 WeakPolarHBondContact O-CG2 3.33Å; I197-T206 HydrophobicContact CB-CG2 4.48Å; I197-T206 HydrophobicContact CG2-CG2 4.09Å; K198-T206 HydrophobicContact CB-CG2 3.71Å; K198-T206 HydrophobicContact CG-CG2 4.45Å; K203-T206 WeakPolarHBondContact O-CB 3.4Å; K203-T206 PolarHBondContact O-N 2.88Å; K203-T206 PolarHBondContact O-OG1 3.03Å; D204-T206 PolarHBondContact O-N 3.39Å; T206-F214 WeakPolarHBondContact O-CD1 3.4Å; T206-F214 WeakPolarHBondContact O-CE1 3.46Å
207N95.1Very high95.2Very high109 Ų10954.6 Ų54.658%0.58328%0.284SS*.  trans-64.2155162.9-67.1-33.1000109.7D204 A215D204-N207 PolarHBondContact O-N 3.4Å; D204-N207 PolarHBondContact O-ND2 3.5Å; N207-A215 PolarHBondContact O-N 2.89Å
208V94.5Very high94.9Very high52 Ų5254.8 Ų54.832%0.31529%0.285SS..BIsolated β-bridgetrans-112.1145.2-174.3-60.30000111.1Y190 G212 G213 F214 R401Y190-V208 VanDerWaalsContact OH-CG1 3.32Å; Y190-V208 WeakPolarHBondContact OH-CG1 3.26Å; V208-G212 WeakPolarHBondContact CG1-O 3.49Å; V208-G213 CarbonylContact C-O 3.55Å; V208-G213 VanDerWaalsContact CA-O 3.23Å; V208-G213 WeakPolarHBondContact CA-O 3.35Å; V208-F214 HydrophobicContact CG1-CD1 4.1Å; V208-F214 HydrophobicContact CG1-CE1 4.08Å; V208-R401 HydrophobicContact CG2-CG 4.46Å
209G88.9Confident94.6Very high12 Ų1252.1 Ų52.112%0.12428%0.276CS..  trans-78-168.8171.300000112.7E211 G212 G213G209-E211 PolarHBondContact O-N 3.48Å; G209-E211 VanDerWaalsContact O-N 3.08Å; G209-G212 PolarHBondContact O-N 3.37Å; G209-G212 VanDerWaalsContact O-N 3.11Å; G209-G213 PolarHBondContact N-O 3.05Å
210D88.7Confident94.4Very high53 Ų5350.7 Ų50.728%0.28327%0.269SS..THydrogen-bonded Turntrans-53.5-33.8-176.6-76.3-4.2000113.2R16 R401 R404R16-D210 WeakPolarHBondContact CD-OD2 3.36Å; D210-R401 PolarHBondContact O-NE 2.87Å; D210-R404 PolarHBondContact O-NH2 2.79Å
211E94.3Very high94.2Very high4 Ų445.4 Ų45.42%0.01925%0.246CC..THydrogen-bonded Turntrans-103.88.2-173.6-60.7-176.7177.400114.3N152 H159 G209 G213 H372 A398N152-E211 PolarHBondContact ND2-OE2 3.22Å; H159-E211 IonicContact CE1-OE1 3.74Å; H159-E211 PolarHBondContact CE1-OE1 2.72Å; H159-E211 VanDerWaalsContact CE1-OE1 3.23Å; H159-E211 IonicContact ND1-OE1 2.84Å; G209-E211 PolarHBondContact O-N 3.48Å; G209-E211 VanDerWaalsContact O-N 3.08Å; E211-G213 VanDerWaalsContact C-N 3.32Å; E211-G213 PolarHBondContact O-N 2.94Å; E211-H372 IonicContact OE1-CE1 3.03Å; E211-H372 IonicContact OE1-NE2 2.71Å; E211-H372 IonicContact OE2-CE1 2.7Å; E211-H372 PolarHBondContact OE2-CE1 2.95Å; E211-H372 IonicContact OE2-NE2 3.2Å; E211-H372 PolarHBondContact OE2-NE2 2.98Å; E211-A398 WeakPolarHBondContact O-CB 3.36Å; E211-A398 PolarHBondContact O-N 3.2Å
212G96.1Very high94.2Very high0 Ų046.9 Ų46.90%025%0.254CS..SBendtrans86.6-7.3175.800000115Y190 V208 G209 A398Y190-G212 WeakPolarHBondContact CE2-O 3.44Å; Y190-G212 PolarHBondContact OH-O 2.94Å; V208-G212 WeakPolarHBondContact CG1-O 3.49Å; G209-G212 PolarHBondContact O-N 3.37Å; G209-G212 VanDerWaalsContact O-N 3.11Å; G212-A398 WeakPolarHBondContact O-CB 3.48Å
213G97.5Very high94.2Very high0 Ų048.1 Ų48.10%025%0.251CS..  trans-71.9155.4171.200000112.1V153 N155 V208 G209 E211V153-G213 WeakPolarHBondContact O-CA 3.5Å; N155-G213 VanDerWaalsContact OD1-CA 3.32Å; N155-G213 WeakPolarHBondContact OD1-CA 3.36Å; V208-G213 CarbonylContact C-O 3.55Å; V208-G213 VanDerWaalsContact CA-O 3.23Å; V208-G213 WeakPolarHBondContact CA-O 3.35Å; G209-G213 PolarHBondContact N-O 3.05Å; E211-G213 VanDerWaalsContact C-N 3.32Å; E211-G213 PolarHBondContact O-N 2.94Å
214F98.2Very high94.3Very high0 Ų041.3 Ų41.30%022%0.222CC..BIsolated β-bridgetrans-75.1150.6179.8-58.9-65.1000111.6V153 I154 N155 Y190 L193 K194 I197 T206 V208 P216V153-F214 WeakPolarHBondContact O-CD2 3.33Å; V153-F214 PolarHBondContact O-N 2.85Å; I154-F214 CarbonylContact C-O 3.59Å; I154-F214 WeakPolarHBondContact CA-O 3.39Å; N155-F214 PolarHBondContact N-O 2.89Å; Y190-F214 HydrophobicContact CD1-CZ 4.36Å; Y190-F214 HydrophobicContact CD2-CD2 4.46Å; Y190-F214 AromaticContact CD2-CE2 3.69Å; Y190-F214 HydrophobicContact CD2-CE2 3.69Å; Y190-F214 HydrophobicContact CD2-CZ 4.14Å; Y190-F214 HydrophobicContact CE1-CE2 4.28Å; Y190-F214 AromaticContact CE1-CZ 3.75Å; Y190-F214 HydrophobicContact CE1-CZ 3.75Å; Y190-F214 HydrophobicContact CE2-CD2 4.02Å; Y190-F214 HydrophobicContact CE2-CE1 4.34Å; Y190-F214 AromaticContact CE2-CE2 3.37Å; Y190-F214 HydrophobicContact CE2-CE2 3.37Å; Y190-F214 AromaticContact CE2-CZ 3.54Å; Y190-F214 HydrophobicContact CE2-CZ 3.54Å; Y190-F214 HydrophobicContact CG-CE2 4.3Å; Y190-F214 AromaticContact CZ-CE1 3.95Å; Y190-F214 AromaticContact CZ-CE2 3.7Å; Y190-F214 AromaticContact CZ-CZ 3.3Å; Y190-F214 WeakPolarHBondContact OH-CZ 3.42Å; L193-F214 HydrophobicContact CB-CE2 4.38Å; L193-F214 HydrophobicContact CD2-CD2 3.89Å; L193-F214 HydrophobicContact CD2-CE2 4.25Å; L193-F214 HydrophobicContact CG-CD2 3.99Å; L193-F214 HydrophobicContact CG-CE2 4.22Å; K194-F214 HydrophobicContact CB-CE1 4.06Å; K194-F214 HydrophobicContact CB-CE2 3.88Å; K194-F214 HydrophobicContact CB-CZ 3.39Å; K194-F214 HydrophobicContact CD-CE1 4.11Å; K194-F214 HydrophobicContact CD-CZ 4.01Å; K194-F214 HydrophobicContact CG-CE1 3.76Å; K194-F214 HydrophobicContact CG-CE2 4.49Å; K194-F214 HydrophobicContact CG-CZ 3.62Å; I197-F214 HydrophobicContact CD1-CB 3.53Å; I197-F214 HydrophobicContact CD1-CD2 3.69Å; I197-F214 HydrophobicContact CD1-CG 3.77Å; T206-F214 WeakPolarHBondContact O-CD1 3.4Å; T206-F214 WeakPolarHBondContact O-CE1 3.46Å; V208-F214 HydrophobicContact CG1-CD1 4.1Å; V208-F214 HydrophobicContact CG1-CE1 4.08Å; F214-P216 VanDerWaalsContact O-CD 3.3Å; F214-P216 WeakPolarHBondContact O-CD 3.4Å
215A95.5Very high94.5Very high30 Ų3035.9 Ų35.925%0.24819%0.192CC..  trans-119.963.7178.100000111.6A160 N207A160-A215 HydrophobicContact CB-CB 3.74Å; N207-A215 PolarHBondContact O-N 2.89Å
216P94.6Very high94.7Very high0 Ų038.4 Ų38.40%020%0.202CC..  trans-63.2149.6176.530-34.6000110.4I154 N162 I197 Y201 A205 F214 I218 L227I154-P216 HydrophobicContact CG2-CG 4.23Å; N162-P216 VanDerWaalsContact CB-O 3.24Å; N162-P216 WeakPolarHBondContact CB-O 3.47Å; N162-P216 PolarHBondContact ND2-O 2.86Å; I197-P216 HydrophobicContact CD1-CG 4.23Å; I197-P216 HydrophobicContact CG2-CB 4.15Å; Y201-P216 HydrophobicContact CD2-CB 3.95Å; Y201-P216 HydrophobicContact CE2-CB 4.17Å; Y201-P216 HydrophobicContact CG-CB 4.39Å; A205-P216 HydrophobicContact CB-CB 4.39Å; F214-P216 VanDerWaalsContact O-CD 3.3Å; F214-P216 WeakPolarHBondContact O-CD 3.4Å; P216-I218 HydrophobicContact CB-CG2 4.3Å; P216-I218 HydrophobicContact CG-CD1 4.02Å; P216-I218 HydrophobicContact CG-CG1 4.18Å; P216-I218 HydrophobicContact CG-CG2 4.44Å; P216-I218 PolarHBondContact O-N 3.31Å; P216-L227 HydrophobicContact CG-CD1 4.4Å
217N90.6Very high94.7Very high121 Ų12137.5 Ų37.565%0.64720%0.197SC*.SBendtrans-78.270.4179.3-170.732.7000111.3
218I92.6Very high94.9Very high3 Ų332.3 Ų32.32%0.01517%0.169CC..  trans-110.8150.6176.660.1178.5000109.7I154 K163 L164 Y201 P216 E223 A224 L227I154-I218 HydrophobicContact CG2-CD1 4.5Å; K163-I218 CarbonylContact C-O 3.58Å; K163-I218 PolarHBondContact N-O 2.86Å; L164-I218 HydrophobicContact CB-CG1 4.23Å; L164-I218 WeakPolarHBondContact CB-O 3.4Å; L164-I218 HydrophobicContact CD1-CD1 4.25Å; L164-I218 HydrophobicContact CD1-CG1 4.2Å; L164-I218 HydrophobicContact CD2-CD1 3.95Å; L164-I218 HydrophobicContact CD2-CG1 4.08Å; L164-I218 HydrophobicContact CG-CG1 4.43Å; L164-I218 PolarHBondContact N-O 3.07Å; Y201-I218 HydrophobicContact CE1-CG2 3.8Å; Y201-I218 HydrophobicContact CE2-CG2 4.2Å; Y201-I218 VanDerWaalsContact OH-CG2 3.32Å; Y201-I218 WeakPolarHBondContact OH-CG2 3.29Å; P216-I218 HydrophobicContact CB-CG2 4.3Å; P216-I218 HydrophobicContact CG-CD1 4.02Å; P216-I218 HydrophobicContact CG-CG1 4.18Å; P216-I218 HydrophobicContact CG-CG2 4.44Å; P216-I218 PolarHBondContact O-N 3.31Å; I218-E223 HydrophobicContact CB-CG 4.48Å; I218-E223 HydrophobicContact CG2-CG 4Å; I218-E223 WeakPolarHBondContact CG2-OE2 3.35Å; I218-A224 HydrophobicContact CD1-CB 3.67Å; I218-L227 HydrophobicContact CD1-CD1 4.31Å
219L91.6Very high95.1Very high60 Ų6034.5 Ų34.531%0.31417%0.174SC..  trans-105.9-48.8174.8172.264.4000110.4K163 N221 D261K163-L219 HydrophobicContact CB-CB 4.01Å; K163-L219 HydrophobicContact CB-CD1 3.68Å; K163-L219 HydrophobicContact CB-CG 4.44Å; K163-L219 HydrophobicContact CD-CD1 4.29Å; L219-N221 PolarHBondContact O-N 3.39Å; L219-D261 HydrophobicContact CD1-CB 3.98Å; L219-D261 WeakPolarHBondContact CD1-OD1 3.14Å
220E93.6Very high95.5Very high119 Ų11937.7 Ų37.756%0.55619%0.188SC*.  trans-74.2122.1-174.1-66.3-63.5160.300111.9K222 E223E220-K222 PolarHBondContact O-N 2.76Å; E220-E223 HydrophobicContact CB-CB 4.17Å; E220-E223 VanDerWaalsContact O-CB 3.28Å; E220-E223 WeakPolarHBondContact O-CB 3.37Å; E220-E223 PolarHBondContact O-N 3.05Å
221N93.2Very high96Very high5 Ų535.2 Ų35.23%0.02718%0.175CC..Hα-helixtrans-60-31.3177.1-57.3-68.3000112.5L164 M166 F169 L219 E223 A224 L225 F284L164-N221 HydrophobicContact CD1-CB 4.32Å; L164-N221 WeakPolarHBondContact CD1-OD1 3.16Å; M166-N221 WeakPolarHBondContact CB-OD1 3.33Å; M166-N221 HydrophobicContact CE-CB 4.03Å; M166-N221 HydrophobicContact CG-CB 4.42Å; M166-N221 WeakPolarHBondContact CG-OD1 2.92Å; M166-N221 PolarHBondContact N-OD1 2.63Å; M166-N221 HydrophobicContact SD-CB 3.7Å; M166-N221 VanDerWaalsContact SD-CG 3.51Å; F169-N221 HydrophobicContact CZ-CB 4.06Å; L219-N221 PolarHBondContact O-N 3.39Å; N221-E223 VanDerWaalsContact C-N 3.26Å; N221-E223 PolarHBondContact O-N 2.94Å; N221-A224 WeakPolarHBondContact O-CB 3.48Å; N221-A224 PolarHBondContact O-N 2.74Å; N221-L225 PolarHBondContact O-N 2.82Å; N221-F284 HydrophobicContact CB-CE2 3.97Å; N221-F284 HydrophobicContact CB-CZ 3.85Å
222K96.1Very high96.2Very high94 Ų9435.3 Ų35.341%0.40918%0.176SC..Hα-helixtrans-61.4-34.8173.8-169.7172.4-176163.10112.4E220 A224 L225 E226 F284 D287 Y288E220-K222 PolarHBondContact O-N 2.76Å; K222-A224 VanDerWaalsContact C-N 3.33Å; K222-A224 PolarHBondContact O-N 3.38Å; K222-L225 PolarHBondContact O-N 3.25Å; K222-E226 PolarHBondContact O-N 3.5Å; K222-F284 HydrophobicContact CB-CE1 4.16Å; K222-D287 IonicContact NZ-OD2 3.29Å; K222-Y288 WeakPolarHBondContact CE-OH 3.36Å; K222-Y288 HydrophobicContact CG-CE2 4.15Å; K222-Y288 WeakPolarHBondContact CG-OH 3.49Å
223E96.9Very high96.3Very high57 Ų5737.9 Ų37.927%0.26620%0.197SC..Hα-helixtrans-67-35.6179-174.6165-146.200111.8K200 Y201 I218 E220 N221 E226 L227K200-E223 IonicContact NZ-OE1 3.4Å; K200-E223 PolarHBondContact NZ-OE1 3.46Å; Y201-E223 WeakPolarHBondContact OH-CG 3.35Å; Y201-E223 PolarHBondContact OH-OE1 3.31Å; I218-E223 HydrophobicContact CB-CG 4.48Å; I218-E223 HydrophobicContact CG2-CG 4Å; I218-E223 WeakPolarHBondContact CG2-OE2 3.35Å; E220-E223 HydrophobicContact CB-CB 4.17Å; E220-E223 VanDerWaalsContact O-CB 3.28Å; E220-E223 WeakPolarHBondContact O-CB 3.37Å; E220-E223 PolarHBondContact O-N 3.05Å; N221-E223 VanDerWaalsContact C-N 3.26Å; N221-E223 PolarHBondContact O-N 2.94Å; E223-E226 PolarHBondContact O-N 3.5Å; E223-L227 VanDerWaalsContact O-CG 3.3Å; E223-L227 WeakPolarHBondContact O-CG 3.46Å; E223-L227 PolarHBondContact O-N 3.26Å
224A97.3Very high96.3Very high0 Ų043.6 Ų43.60%022%0.221CC..Hα-helixtrans-61.3-45.4172.600000111.4I154 L164 F169 I218 N221 K222 E226 L227 L228I154-A224 HydrophobicContact CD1-CB 4.2Å; I154-A224 HydrophobicContact CG2-CB 4.42Å; L164-A224 HydrophobicContact CD2-CB 4.35Å; F169-A224 HydrophobicContact CD1-CB 3.77Å; F169-A224 HydrophobicContact CD2-CB 3.95Å; F169-A224 HydrophobicContact CE1-CB 3.63Å; F169-A224 HydrophobicContact CE2-CB 3.88Å; F169-A224 HydrophobicContact CG-CB 3.93Å; F169-A224 HydrophobicContact CZ-CB 3.7Å; I218-A224 HydrophobicContact CD1-CB 3.67Å; N221-A224 WeakPolarHBondContact O-CB 3.48Å; N221-A224 PolarHBondContact O-N 2.74Å; K222-A224 VanDerWaalsContact C-N 3.33Å; K222-A224 PolarHBondContact O-N 3.38Å; A224-E226 PolarHBondContact O-N 2.8Å; A224-L227 WeakPolarHBondContact O-CB 3.4Å; A224-L227 PolarHBondContact O-N 2.98Å; A224-L228 WeakPolarHBondContact O-CG 3.41Å; A224-L228 PolarHBondContact O-N 3.26Å
225L98.3Very high96.3Very high0 Ų044.4 Ų44.40%023%0.229CC..Hα-helixtrans-63.6-39.1177.8-66171.9000112.5F169 N221 K222 L228 K229 I243 M245 F284 Y288 V290F169-L225 HydrophobicContact CD1-CD2 3.84Å; F169-L225 HydrophobicContact CD1-CG 4.15Å; F169-L225 HydrophobicContact CE1-CD2 4.17Å; F169-L225 HydrophobicContact CE1-CG 4.04Å; N221-L225 PolarHBondContact O-N 2.82Å; K222-L225 PolarHBondContact O-N 3.25Å; L225-L228 PolarHBondContact O-N 3Å; L225-K229 WeakPolarHBondContact O-CB 3.48Å; L225-K229 PolarHBondContact O-N 3.36Å; L225-I243 HydrophobicContact CD2-CD1 4.13Å; L225-I243 HydrophobicContact CD2-CG2 3.84Å; L225-M245 HydrophobicContact CD1-SD 4.34Å; L225-M245 HydrophobicContact CD2-SD 4.05Å; L225-F284 HydrophobicContact CD1-CB 3.83Å; L225-F284 HydrophobicContact CD1-CD1 3.83Å; L225-F284 HydrophobicContact CD1-CD2 3.82Å; L225-F284 HydrophobicContact CD1-CE1 4.33Å; L225-F284 HydrophobicContact CD1-CE2 4.31Å; L225-F284 HydrophobicContact CD1-CG 3.56Å; L225-Y288 HydrophobicContact CB-CD1 3.81Å; L225-Y288 HydrophobicContact CB-CD2 3.96Å; L225-Y288 HydrophobicContact CB-CE1 3.8Å; L225-Y288 HydrophobicContact CB-CE2 3.94Å; L225-Y288 HydrophobicContact CB-CG 3.9Å; L225-Y288 HydrophobicContact CD1-CD2 3.56Å; L225-Y288 HydrophobicContact CD1-CE2 3.83Å; L225-Y288 HydrophobicContact CD1-CG 4.11Å; L225-Y288 HydrophobicContact CG-CD2 4.31Å; L225-Y288 HydrophobicContact CG-CG 4.46Å; L225-V290 HydrophobicContact CD2-CG2 4.09Å
226E98.1Very high96.5Very high65 Ų6545.9 Ų45.930%0.30425%0.247SC..Hα-helixtrans-64.5-39.6173.6-73.2-59.8156.400112.6K222 E223 A224 L228 K229 N230 Y288K222-E226 PolarHBondContact O-N 3.5Å; E223-E226 PolarHBondContact O-N 3.5Å; A224-E226 PolarHBondContact O-N 2.8Å; E226-L228 VanDerWaalsContact C-N 3.33Å; E226-L228 PolarHBondContact O-N 3.45Å; E226-K229 PolarHBondContact O-N 3.42Å; E226-N230 WeakPolarHBondContact O-CB 3.37Å; E226-N230 VanDerWaalsContact O-CG 3.22Å; E226-N230 PolarHBondContact O-N 3.05Å; E226-N230 PolarHBondContact O-ND2 2.83Å; E226-N230 VanDerWaalsContact O-ND2 3.13Å; E226-Y288 HydrophobicContact CG-CE1 4.2Å; E226-Y288 WeakPolarHBondContact CG-OH 3.23Å; E226-Y288 WeakPolarHBondContact OE1-CE1 3.17Å; E226-Y288 VanDerWaalsContact OE1-CZ 3.24Å; E226-Y288 PolarHBondContact OE1-OH 2.64Å
227L98.1Very high96.6Very high4 Ų447.2 Ų47.22%0.02125%0.252CS..Hα-helixtrans-61.3-43.4174.4-68.5168.4000111.3I154 L193 V196 I197 K200 Y201 P216 I218 E223 A224 N230 A231I154-L227 HydrophobicContact CD1-CB 4.13Å; I154-L227 HydrophobicContact CD1-CD1 4.34Å; L193-L227 HydrophobicContact CD1-CB 4.05Å; V196-L227 HydrophobicContact CG1-CD2 3.75Å; I197-L227 HydrophobicContact CG1-CD1 4.44Å; K200-L227 HydrophobicContact CD-CD2 4.27Å; Y201-L227 HydrophobicContact CE2-CD1 3.74Å; Y201-L227 HydrophobicContact CE2-CD2 3.88Å; Y201-L227 HydrophobicContact CE2-CG 4.42Å; P216-L227 HydrophobicContact CG-CD1 4.4Å; I218-L227 HydrophobicContact CD1-CD1 4.31Å; E223-L227 VanDerWaalsContact O-CG 3.3Å; E223-L227 WeakPolarHBondContact O-CG 3.46Å; E223-L227 PolarHBondContact O-N 3.26Å; A224-L227 WeakPolarHBondContact O-CB 3.4Å; A224-L227 PolarHBondContact O-N 2.98Å; L227-N230 PolarHBondContact O-N 3.29Å; L227-A231 WeakPolarHBondContact O-CB 3.43Å; L227-A231 PolarHBondContact O-N 2.79Å
228L98.3Very high97Very high0 Ų045.6 Ų45.60%025%0.247CC..Hα-helixtrans-63.7-48.3176.4-66.3-168.1000111.9V153 I154 F169 I171 L193 A224 L225 E226 N230 A231 I232 I243V153-L228 HydrophobicContact CG2-CD1 4.36Å; V153-L228 HydrophobicContact CG2-CD2 3.46Å; V153-L228 VanDerWaalsContact CG2-CD2 3.46Å; I154-L228 HydrophobicContact CD1-CD2 3.69Å; I154-L228 HydrophobicContact CD1-CG 3.99Å; I154-L228 HydrophobicContact CG1-CD2 4.02Å; F169-L228 HydrophobicContact CB-CD1 3.77Å; I171-L228 HydrophobicContact CG2-CD1 4.27Å; I171-L228 HydrophobicContact CG2-CD2 4.4Å; L193-L228 HydrophobicContact CD1-CD2 4.13Å; L193-L228 HydrophobicContact CD2-CD2 3.66Å; A224-L228 WeakPolarHBondContact O-CG 3.41Å; A224-L228 PolarHBondContact O-N 3.26Å; L225-L228 PolarHBondContact O-N 3Å; E226-L228 VanDerWaalsContact C-N 3.33Å; E226-L228 PolarHBondContact O-N 3.45Å; L228-N230 VanDerWaalsContact C-N 3.28Å; L228-N230 PolarHBondContact O-N 2.93Å; L228-A231 PolarHBondContact O-N 2.71Å; L228-A231 VanDerWaalsContact O-N 3.14Å; L228-I232 WeakPolarHBondContact O-CB 3.09Å; L228-I232 WeakPolarHBondContact O-CD1 3.4Å; L228-I232 WeakPolarHBondContact O-CG1 3.22Å; L228-I232 PolarHBondContact O-N 3.4Å; L228-I243 HydrophobicContact CB-CD1 4.02Å; L228-I243 HydrophobicContact CD1-CD1 4.17Å; L228-I243 HydrophobicContact CD1-CG1 4.32Å; L228-I243 HydrophobicContact CD1-CG2 4.24Å
229K97.8Very high97.2Very high98 Ų9852.8 Ų52.843%0.42629%0.285SS..Hα-helixtrans-54.7-45.8177-178.7-179.5176.7-179.70111.5L225 E226 A233 Y288L225-K229 WeakPolarHBondContact O-CB 3.48Å; L225-K229 PolarHBondContact O-N 3.36Å; E226-K229 PolarHBondContact O-N 3.42Å; K229-A233 WeakPolarHBondContact O-CB 3.5Å; K229-A233 PolarHBondContact O-N 3.1Å; K229-Y288 HydrophobicContact CD-CD1 4.27Å; K229-Y288 HydrophobicContact CD-CE1 4.23Å
230N98Very high97.5Very high79 Ų7953.4 Ų53.442%0.42229%0.285SS..Hα-helixtrans-65.4-42.3177.3-72.1-29.1000112.5E226 L227 L228 A233 K234E226-N230 WeakPolarHBondContact O-CB 3.37Å; E226-N230 VanDerWaalsContact O-CG 3.22Å; E226-N230 PolarHBondContact O-N 3.05Å; E226-N230 PolarHBondContact O-ND2 2.83Å; E226-N230 VanDerWaalsContact O-ND2 3.13Å; L227-N230 PolarHBondContact O-N 3.29Å; L228-N230 VanDerWaalsContact C-N 3.28Å; L228-N230 PolarHBondContact O-N 2.93Å; N230-A233 PolarHBondContact O-N 3.07Å; N230-K234 WeakPolarHBondContact O-CB 3.27Å; N230-K234 WeakPolarHBondContact O-CG 3.44Å; N230-K234 PolarHBondContact O-N 2.86Å
231A98.4Very high97.8Very high0 Ų048 Ų480%026%0.26CS..Hα-helixtrans-65.8-42.8178.300000112.4V189 L193 L227 L228 K234 A235V189-A231 HydrophobicContact CG1-CB 4.27Å; L193-A231 HydrophobicContact CB-CB 3.67Å; L193-A231 HydrophobicContact CD1-CB 3.91Å; L193-A231 HydrophobicContact CG-CB 4.39Å; L227-A231 WeakPolarHBondContact O-CB 3.43Å; L227-A231 PolarHBondContact O-N 2.79Å; L228-A231 PolarHBondContact O-N 2.71Å; L228-A231 VanDerWaalsContact O-N 3.14Å; A231-K234 PolarHBondContact O-N 3.21Å; A231-A235 WeakPolarHBondContact O-CB 3.38Å; A231-A235 PolarHBondContact O-N 3.4Å
232I98.6Very high98Very high7 Ų748.9 Ų48.94%0.03627%0.266CS..Hα-helixtrans-61.3-45176.1-68163.4000110.4I171 V189 L228 A235 G236 Y237 I241 I243I171-I232 HydrophobicContact CG2-CD1 4.2Å; V189-I232 HydrophobicContact CG1-CG1 3.83Å; L228-I232 WeakPolarHBondContact O-CB 3.09Å; L228-I232 WeakPolarHBondContact O-CD1 3.4Å; L228-I232 WeakPolarHBondContact O-CG1 3.22Å; L228-I232 PolarHBondContact O-N 3.4Å; I232-A235 PolarHBondContact O-N 3.27Å; I232-G236 PolarHBondContact O-N 3.46Å; I232-Y237 PolarHBondContact O-N 3.33Å; I232-Y237 VanDerWaalsContact O-N 3.1Å; I232-I241 HydrophobicContact CD1-CB 4.29Å; I232-I241 HydrophobicContact CD1-CG2 3.63Å; I232-I241 HydrophobicContact CG1-CB 4.38Å; I232-I241 HydrophobicContact CG1-CD1 4.23Å; I232-I241 HydrophobicContact CG1-CG2 4Å; I232-I241 HydrophobicContact CG2-CB 4.18Å; I232-I241 HydrophobicContact CG2-CD1 4.38Å; I232-I243 HydrophobicContact CD1-CD1 4.47Å; I232-I243 HydrophobicContact CD1-CG1 4.36Å
233A98.4Very high98.2Very high53 Ų5344.4 Ų44.444%0.43825%0.246SC..Hα-helixtrans-65.2-45.7177.500000112.1K229 N230 A235 G236K229-A233 WeakPolarHBondContact O-CB 3.5Å; K229-A233 PolarHBondContact O-N 3.1Å; N230-A233 PolarHBondContact O-N 3.07Å; A233-A235 PolarHBondContact O-N 2.83Å; A233-G236 PolarHBondContact O-N 2.82Å
234K98.3Very high98.3Very high120 Ų12041.8 Ų41.852%0.52223%0.234SC..Hα-helixtrans-59.9-32.9176-79.8-170.9177.8-171.80112.4V196 E199 N230 A231 G236V196-K234 HydrophobicContact CG2-CD 3.7Å; E199-K234 IonicContact OE2-NZ 2.7Å; E199-K234 PolarHBondContact OE2-NZ 2.82Å; N230-K234 WeakPolarHBondContact O-CB 3.27Å; N230-K234 WeakPolarHBondContact O-CG 3.44Å; N230-K234 PolarHBondContact O-N 2.86Å; A231-K234 PolarHBondContact O-N 3.21Å; K234-G236 VanDerWaalsContact C-N 3.33Å
235A98.4Very high98.3Very high18 Ų1841.8 Ų41.815%0.14923%0.234CC..THydrogen-bonded Turntrans-80.6-9.517600000114.1V189 N192 A231 I232 A233 Y237V189-A235 HydrophobicContact CG2-CB 3.69Å; N192-A235 HydrophobicContact CB-CB 4.38Å; A231-A235 WeakPolarHBondContact O-CB 3.38Å; A231-A235 PolarHBondContact O-N 3.4Å; I232-A235 PolarHBondContact O-N 3.27Å; A233-A235 PolarHBondContact O-N 2.83Å; A235-Y237 HydrophobicContact CB-CD2 3.71Å; A235-Y237 HydrophobicContact CB-CE2 4.13Å; A235-Y237 WeakPolarHBondContact O-CD2 3.43Å; A235-Y237 VanDerWaalsContact O-CE2 3.31Å; A235-Y237 WeakPolarHBondContact O-CE2 3.3Å
236G98.4Very high98.3Very high61 Ų6141.8 Ų41.863%0.62923%0.234SC*.THydrogen-bonded Turntrans78.625.4179.100000114.9I232 A233 K234I232-G236 PolarHBondContact O-N 3.46Å; A233-G236 PolarHBondContact O-N 2.82Å; K234-G236 VanDerWaalsContact C-N 3.33Å
237Y98.6Very high98.4Very high27 Ų2738.7 Ų38.711%0.10622%0.22CC..  trans-119.724.3-173.1-62.9-54.8000115.2R184 I185 E188 V189 I232 A235 D239 K240 I241R184-Y237 PolarHBondContact NH1-OH 3.13Å; I185-Y237 HydrophobicContact CB-CD2 4.5Å; I185-Y237 HydrophobicContact CB-CE2 4.45Å; I185-Y237 HydrophobicContact CD1-CD1 4.38Å; I185-Y237 HydrophobicContact CD1-CE1 4.31Å; I185-Y237 HydrophobicContact CG1-CD1 4.12Å; I185-Y237 HydrophobicContact CG1-CD2 4.5Å; I185-Y237 HydrophobicContact CG1-CE1 3.82Å; I185-Y237 HydrophobicContact CG1-CE2 4.23Å; I185-Y237 HydrophobicContact CG1-CG 4.46Å; I185-Y237 HydrophobicContact CG2-CD1 4.29Å; I185-Y237 HydrophobicContact CG2-CD2 3.86Å; I185-Y237 HydrophobicContact CG2-CE2 4.29Å; I185-Y237 HydrophobicContact CG2-CG 3.87Å; E188-Y237 HydrophobicContact CB-CE2 4.1Å; E188-Y237 WeakPolarHBondContact OE2-CE2 3.41Å; E188-Y237 VanDerWaalsContact OE2-CZ 3.25Å; E188-Y237 PolarHBondContact OE2-OH 2.75Å; V189-Y237 HydrophobicContact CG2-CD2 3.87Å; I232-Y237 PolarHBondContact O-N 3.33Å; I232-Y237 VanDerWaalsContact O-N 3.1Å; A235-Y237 HydrophobicContact CB-CD2 3.71Å; A235-Y237 HydrophobicContact CB-CE2 4.13Å; A235-Y237 WeakPolarHBondContact O-CD2 3.43Å; A235-Y237 VanDerWaalsContact O-CE2 3.31Å; A235-Y237 WeakPolarHBondContact O-CE2 3.3Å; Y237-D239 PolarHBondContact O-N 3.31Å; Y237-K240 HydrophobicContact CD1-CD 4.09Å; Y237-K240 PolarHBondContact O-N 2.82Å; Y237-I241 PolarHBondContact O-N 3.35Å; Y237-I241 VanDerWaalsContact O-N 3.17Å
238T98.1Very high98.3Very high88 Ų8838.6 Ų38.654%0.5422%0.22SC..THydrogen-bonded Turntrans-51.6-40.2-179.3-56.40000113.3K240T238-K240 VanDerWaalsContact C-N 3.35Å
239D97.3Very high98.3Very high154 Ų15438.6 Ų38.682%0.82422%0.22SC*.THydrogen-bonded Turntrans-86.8-2.8-178.4-57.6-42.3000114.1Y237Y237-D239 PolarHBondContact O-N 3.31Å
240K98.3Very high98.3Very high73 Ų7334.9 Ų34.932%0.31721%0.206SC..THydrogen-bonded Turntrans-111.7-19.1-175.1-68-163176.8-170.70114.3P173 V174 G175 D181 I185 Y237 T238P173-K240 CarbonylContact C-O 3.53Å; P173-K240 VanDerWaalsContact C-O 3.32Å; P173-K240 WeakPolarHBondContact CA-O 3.4Å; V174-K240 PolarHBondContact N-O 2.79Å; V174-K240 VanDerWaalsContact N-O 3.16Å; G175-K240 PolarHBondContact N-O 3.39Å; D181-K240 IonicContact OD2-NZ 3.63Å; I185-K240 HydrophobicContact CD1-CD 3.7Å; Y237-K240 HydrophobicContact CD1-CD 4.09Å; Y237-K240 PolarHBondContact O-N 2.82Å; T238-K240 VanDerWaalsContact C-N 3.35Å
241I98.6Very high98.1Very high4 Ų434.4 Ų34.42%0.02120%0.201CC..  trans-116.6136.8-174.6-64.6174.3000110.6I171 L172 P173 I185 V189 I232 Y237I171-I241 HydrophobicContact CB-CG2 3.78Å; I171-I241 HydrophobicContact CG2-CG2 4.08Å; L172-I241 WeakPolarHBondContact O-CA 3.14Å; P173-I241 HydrophobicContact CB-CG1 4.32Å; I185-I241 HydrophobicContact CG2-CD1 3.56Å; I185-I241 HydrophobicContact CG2-CG1 3.76Å; V189-I241 HydrophobicContact CB-CD1 4.17Å; V189-I241 HydrophobicContact CG1-CD1 4.45Å; V189-I241 HydrophobicContact CG2-CD1 3.22Å; I232-I241 HydrophobicContact CD1-CB 4.29Å; I232-I241 HydrophobicContact CD1-CG2 3.63Å; I232-I241 HydrophobicContact CG1-CB 4.38Å; I232-I241 HydrophobicContact CG1-CD1 4.23Å; I232-I241 HydrophobicContact CG1-CG2 4Å; I232-I241 HydrophobicContact CG2-CB 4.18Å; I232-I241 HydrophobicContact CG2-CD1 4.38Å; Y237-I241 PolarHBondContact O-N 3.35Å; Y237-I241 VanDerWaalsContact O-N 3.17Å
242V98.8Very high98Very high25 Ų2534.5 Ų34.515%0.15220%0.201CC..EExtended strand (participates in β ladder)trans-118.5166.9167.6-63.40000109.4L172 V174 P289 V291L172-V242 HydrophobicContact CB-CG2 3.8Å; L172-V242 PolarHBondContact N-O 2.81Å; L172-V242 PolarHBondContact O-N 3.17Å; V174-V242 HydrophobicContact CB-CG2 4.33Å; V174-V242 HydrophobicContact CG1-CG2 3.61Å; V174-V242 HydrophobicContact CG2-CB 4.41Å; V174-V242 HydrophobicContact CG2-CG1 3.87Å; V174-V242 HydrophobicContact CG2-CG2 3.72Å; V242-P289 WeakPolarHBondContact CB-O 3.21Å; V242-P289 HydrophobicContact CG1-CB 4.49Å; V242-V291 HydrophobicContact CB-CB 4.43Å; V242-V291 HydrophobicContact CB-CG1 3.81Å; V242-V291 HydrophobicContact CB-CG2 3.75Å; V242-V291 HydrophobicContact CG1-CG1 3.93Å; V242-V291 HydrophobicContact CG2-CB 4.4Å; V242-V291 HydrophobicContact CG2-CG1 4.2Å; V242-V291 HydrophobicContact CG2-CG2 3.34Å
243I98.9Very high98Very high0 Ų037.9 Ų37.90%021%0.214CC..EExtended strand (participates in β ladder)trans-107.9138.5-175.8-64.7172.8000110.1M170 L225 L228 I232 M245 P289 V290 V291M170-I243 WeakPolarHBondContact O-CA 3.42Å; L225-I243 HydrophobicContact CD2-CD1 4.13Å; L225-I243 HydrophobicContact CD2-CG2 3.84Å; L228-I243 HydrophobicContact CB-CD1 4.02Å; L228-I243 HydrophobicContact CD1-CD1 4.17Å; L228-I243 HydrophobicContact CD1-CG1 4.32Å; L228-I243 HydrophobicContact CD1-CG2 4.24Å; I232-I243 HydrophobicContact CD1-CD1 4.47Å; I232-I243 HydrophobicContact CD1-CG1 4.36Å; I243-M245 HydrophobicContact CG2-CG 4.26Å; I243-P289 HydrophobicContact CD1-CG 4.26Å; I243-P289 HydrophobicContact CG1-CG 4.35Å; I243-P289 PolarHBondContact N-O 2.95Å; I243-V290 HydrophobicContact CB-CG2 4.11Å; I243-V290 HydrophobicContact CG2-CG2 3.98Å; I243-V290 CarbonylContact O-C 3.57Å; I243-V290 WeakPolarHBondContact O-CA 3.31Å; I243-V291 PolarHBondContact O-N 3.49Å
244G98.8Very high97.9Very high1 Ų139 Ų391%0.0121%0.209CC..EExtended strand (participates in β ladder)trans-113.9155.1165.200000109.8M170 S292M170-G244 WeakPolarHBondContact CA-O 3.04Å; M170-G244 PolarHBondContact N-O 3.4Å; M170-G244 PolarHBondContact O-N 3.17Å; G244-S292 CarbonylContact C-O 3.59Å; G244-S292 VanDerWaalsContact CA-O 3.3Å; G244-S292 WeakPolarHBondContact CA-O 3.46Å
245M98.8Very high97.5Very high0 Ų037.2 Ų37.20%023%0.225CC..EExtended strand (participates in β ladder)trans-134.4139.5176.8-61.3174.959.200109.4M166 E168 F169 L225 I243 F284 V290 S292 I293 E294M166-M245 HydrophobicContact SD-CE 3.27Å; M166-M245 WeakPolarHBondContact SD-CE 3.37Å; E168-M245 WeakPolarHBondContact O-CA 3.26Å; F169-M245 HydrophobicContact CD1-CE 4.14Å; F169-M245 HydrophobicContact CD1-CG 4.25Å; F169-M245 HydrophobicContact CE1-CE 3.55Å; F169-M245 HydrophobicContact CE1-SD 4.41Å; F169-M245 HydrophobicContact CZ-CE 4.12Å; L225-M245 HydrophobicContact CD1-SD 4.34Å; L225-M245 HydrophobicContact CD2-SD 4.05Å; I243-M245 HydrophobicContact CG2-CG 4.26Å; M245-F284 HydrophobicContact CE-CD2 3.93Å; M245-F284 HydrophobicContact CE-CE2 4.15Å; M245-F284 HydrophobicContact SD-CD2 4.2Å; M245-V290 HydrophobicContact CG-CG1 4.46Å; M245-V290 HydrophobicContact SD-CG1 4.15Å; M245-V290 HydrophobicContact SD-CG2 4.05Å; M245-S292 PolarHBondContact N-O 2.66Å; M245-I293 CarbonylContact O-C 3.59Å; M245-I293 WeakPolarHBondContact O-CA 3.34Å; M245-E294 WeakPolarHBondContact O-CB 3.39Å; M245-E294 PolarHBondContact O-N 3.18Å
246D98.4Very high97.4Very high1 Ų137.9 Ų37.91%0.00523%0.234CC..EExtended strand (participates in β ladder)trans-109.7116.6158.7169.623.5000107.8Q167 E168 M170 A248 E294 K395Q167-D246 PolarHBondContact N-O 3.16Å; Q167-D246 PolarHBondContact NE2-OD2 2.93Å; E168-D246 HydrophobicContact CB-CB 3.93Å; E168-D246 HydrophobicContact CG-CB 4.03Å; E168-D246 PolarHBondContact N-O 2.96Å; E168-D246 PolarHBondContact O-N 2.55Å; M170-D246 HydrophobicContact CE-CB 4.2Å; D246-A248 PolarHBondContact OD1-N 3.48Å; D246-E294 HydrophobicContact CB-CB 4Å; D246-E294 HydrophobicContact CB-CG 4.12Å; D246-E294 VanDerWaalsContact CG-OE1 3.27Å; D246-K395 IonicContact OD2-NZ 3.51Å; D246-K395 PolarHBondContact OD2-NZ 3.46Å
247V98.4Very high97.4Very high0 Ų039.1 Ų39.10%022%0.222CC..  trans-83.9-36.7-178.2-176.70000109.8M166 Q167 A249 F252 Y281 I293 E294 D295M166-V247 HydrophobicContact CE-CG1 4.44Å; M166-V247 HydrophobicContact CG-CB 4.4Å; M166-V247 HydrophobicContact CG-CG1 3.84Å; M166-V247 HydrophobicContact CG-CG2 4.43Å; M166-V247 HydrophobicContact SD-CG1 4.47Å; M166-V247 HydrophobicContact SD-CG2 4.3Å; Q167-V247 PolarHBondContact N-O 3.41Å; V247-A249 VanDerWaalsContact C-N 3.34Å; V247-A249 HydrophobicContact CG1-CB 4.06Å; V247-F252 HydrophobicContact CG1-CE1 3.94Å; V247-F252 HydrophobicContact CG1-CZ 3.48Å; V247-F252 VanDerWaalsContact CG1-CZ 3.48Å; V247-F252 WeakPolarHBondContact O-CE1 3.48Å; V247-Y281 HydrophobicContact CG1-CE1 4.25Å; V247-Y281 WeakPolarHBondContact CG1-OH 3.46Å; V247-Y281 HydrophobicContact CG2-CE1 3.76Å; V247-I293 HydrophobicContact CG2-CG2 3.75Å; V247-E294 PolarHBondContact N-O 2.52Å; V247-D295 WeakPolarHBondContact CB-O 3.5Å
248A96.9Very high97.4Very high2 Ų237.9 Ų37.92%0.01722%0.217CC..  trans49.950.4-170.400000112.7Q167 D246 S250 E251Q167-A248 HydrophobicContact CB-CB 3.78Å; Q167-A248 HydrophobicContact CG-CB 4.4Å; D246-A248 PolarHBondContact OD1-N 3.48Å; A248-S250 PolarHBondContact O-N 3.49Å; A248-S250 VanDerWaalsContact O-N 3.09Å; A248-E251 HydrophobicContact CB-CG 4.25Å; A248-E251 WeakPolarHBondContact O-CB 3.26Å; A248-E251 PolarHBondContact O-N 2.89Å
249A98Very high97.4Very high0 Ų033.7 Ų33.70%019%0.191CC..G310 helixtrans-62.5-22-168.100000115.3V247 E251 F252 Y253 Y258 D295V247-A249 VanDerWaalsContact C-N 3.34Å; V247-A249 HydrophobicContact CG1-CB 4.06Å; A249-E251 PolarHBondContact O-N 3.27Å; A249-F252 HydrophobicContact CB-CE1 4.39Å; A249-F252 HydrophobicContact CB-CE2 4.01Å; A249-F252 HydrophobicContact CB-CZ 3.79Å; A249-F252 CarbonylContact O-C 3.51Å; A249-F252 PolarHBondContact O-N 2.98Å; A249-Y253 PolarHBondContact O-N 2.75Å; A249-Y253 VanDerWaalsContact O-N 3.09Å; A249-Y258 HydrophobicContact CB-CD1 4.13Å; A249-Y258 HydrophobicContact CB-CE1 3.85Å; A249-D295 VanDerWaalsContact CB-O 3.25Å; A249-D295 WeakPolarHBondContact CB-O 3.26Å; A249-D295 PolarHBondContact N-O 3.36Å; A249-D295 VanDerWaalsContact N-O 3.08Å
250S97Very high97.4Very high19 Ų1928 Ų2813%0.13316%0.161CC..G310 helixtrans-56.9-32.5172.3-82.20000113.3A248 F252 Y253 D298 Q299A248-S250 PolarHBondContact O-N 3.49Å; A248-S250 VanDerWaalsContact O-N 3.09Å; S250-F252 PolarHBondContact O-N 2.84Å; S250-Y253 PolarHBondContact O-N 3.4Å; S250-D298 WeakPolarHBondContact CA-OD1 3.47Å; S250-D298 WeakPolarHBondContact CB-OD1 3.39Å; S250-D298 WeakPolarHBondContact OG-CA 3.47Å; S250-D298 PolarHBondContact OG-OD1 3.46Å; S250-Q299 PolarHBondContact OG-N 2.96Å
251E95.2Very high97.3Very high70 Ų7026 Ų2633%0.32715%0.153SC..G310 helixtrans-66-24-178.3-64.9-66.9112.500112.8S158 A248 A249S158-E251 PolarHBondContact OG-OE2 2.97Å; A248-E251 HydrophobicContact CB-CG 4.25Å; A248-E251 WeakPolarHBondContact O-CB 3.26Å; A248-E251 PolarHBondContact O-N 2.89Å; A249-E251 PolarHBondContact O-N 3.27Å
252F96.7Very high97.1Very high1 Ų127.7 Ų27.70%0.00416%0.161CC..G310 helixtrans-123.917.5-179.159.1-102.7000113.6A165 V247 A249 S250 Y258 D259 L260 F262 L277A165-F252 HydrophobicContact CB-CD1 4.3Å; A165-F252 HydrophobicContact CB-CE1 4.38Å; V247-F252 HydrophobicContact CG1-CE1 3.94Å; V247-F252 HydrophobicContact CG1-CZ 3.48Å; V247-F252 VanDerWaalsContact CG1-CZ 3.48Å; V247-F252 WeakPolarHBondContact O-CE1 3.48Å; A249-F252 HydrophobicContact CB-CE1 4.39Å; A249-F252 HydrophobicContact CB-CE2 4.01Å; A249-F252 HydrophobicContact CB-CZ 3.79Å; A249-F252 CarbonylContact O-C 3.51Å; A249-F252 PolarHBondContact O-N 2.98Å; S250-F252 PolarHBondContact O-N 2.84Å; F252-Y258 AromaticContact CD2-CD1 3.9Å; F252-Y258 HydrophobicContact CD2-CD1 3.9Å; F252-Y258 HydrophobicContact CD2-CG 4.4Å; F252-Y258 AromaticContact CE2-CD1 3.76Å; F252-Y258 HydrophobicContact CE2-CD1 3.76Å; F252-Y258 HydrophobicContact CE2-CG 4.23Å; F252-Y258 WeakPolarHBondContact O-CA 3.26Å; F252-D259 VanDerWaalsContact CB-O 3.29Å; F252-D259 WeakPolarHBondContact CB-O 3.49Å; F252-D259 PolarHBondContact O-N 3.11Å; F252-L260 HydrophobicContact CD2-CD2 4.38Å; F252-L260 HydrophobicContact CE2-CD2 3.81Å; F252-L260 HydrophobicContact CZ-CD2 4.02Å; F252-F262 HydrophobicContact CB-CB 3.79Å; F252-F262 HydrophobicContact CB-CD1 3.51Å; F252-F262 HydrophobicContact CB-CD2 4.44Å; F252-F262 HydrophobicContact CB-CE1 4.14Å; F252-F262 HydrophobicContact CB-CG 3.67Å; F252-F262 HydrophobicContact CD1-CD1 4.27Å; F252-F262 HydrophobicContact CD1-CE1 4.2Å; F252-F262 HydrophobicContact CG-CD1 4.26Å; F252-L277 HydrophobicContact CE2-CD2 4.39Å
253Y97.8Very high96.9Very high78 Ų7829.7 Ų29.731%0.30617%0.167SC..EExtended strand (participates in β ladder)trans-74.3131.1170.8-178.9-114.1000111A249 S250 G256 K257 Y258 D298A249-Y253 PolarHBondContact O-N 2.75Å; A249-Y253 VanDerWaalsContact O-N 3.09Å; S250-Y253 PolarHBondContact O-N 3.4Å; Y253-G256 VanDerWaalsContact CZ-N 3.3Å; Y253-G256 VanDerWaalsContact OH-CA 3.24Å; Y253-G256 WeakPolarHBondContact OH-CA 3.5Å; Y253-G256 PolarHBondContact OH-N 3.37Å; Y253-K257 CarbonylContact C-O 3.57Å; Y253-K257 WeakPolarHBondContact CA-O 3.41Å; Y253-K257 WeakPolarHBondContact CD2-O 3.12Å; Y253-Y258 HydrophobicContact CD2-CD1 4.04Å; Y253-Y258 AromaticContact CD2-CE1 3.56Å; Y253-Y258 HydrophobicContact CD2-CE1 3.56Å; Y253-Y258 HydrophobicContact CD2-CE2 4.21Å; Y253-Y258 AromaticContact CD2-CZ 3.64Å; Y253-Y258 HydrophobicContact CE2-CE1 4.46Å; Y253-Y258 HydrophobicContact CE2-CE2 4.45Å; Y253-Y258 HydrophobicContact CG-CE1 4.25Å; Y253-D298 HydrophobicContact CD1-CB 3.91Å; Y253-D298 HydrophobicContact CD2-CB 3.82Å; Y253-D298 HydrophobicContact CE1-CB 4.32Å; Y253-D298 HydrophobicContact CE2-CB 4.24Å; Y253-D298 HydrophobicContact CG-CB 3.62Å
254K96.2Very high96.7Very high76 Ų7630.5 Ų30.533%0.3317%0.173SC..EExtended strand (participates in β ladder)trans-137.790.8-174.3-60.6-67.2-179.1173.50110.1G256 K257 D259 D266 Y271K254-G256 PolarHBondContact O-N 2.76Å; K254-K257 PolarHBondContact N-O 3.38Å; K254-K257 PolarHBondContact O-N 3.14Å; K254-K257 VanDerWaalsContact O-N 3.16Å; K254-D259 HydrophobicContact CG-CB 4.1Å; K254-D266 IonicContact NZ-OD1 3.66Å; K254-Y271 HydrophobicContact CB-CD2 3.81Å; K254-Y271 HydrophobicContact CB-CE2 3.45Å; K254-Y271 VanDerWaalsContact CB-CE2 3.45Å; K254-Y271 HydrophobicContact CG-CD2 4.49Å; K254-Y271 HydrophobicContact CG-CE1 4.36Å; K254-Y271 HydrophobicContact CG-CE2 3.9Å
255G89.6Confident96.5Very high84 Ų8436 Ų3687%0.86621%0.208SC*.THydrogen-bonded Turntrans56.647168.600000114.7
256G96.4Very high96.4Very high31 Ų3141 Ų4132%0.3224%0.235SC..THydrogen-bonded Turntrans92.11.2-178.800000115Y253 K254Y253-G256 VanDerWaalsContact CZ-N 3.3Å; Y253-G256 VanDerWaalsContact OH-CA 3.24Å; Y253-G256 WeakPolarHBondContact OH-CA 3.5Å; Y253-G256 PolarHBondContact OH-N 3.37Å; K254-G256 PolarHBondContact O-N 2.76Å
257K98.4Very high96.3Very high88 Ų8844.3 Ų44.338%0.38325%0.253SS..EExtended strand (participates in β ladder)trans-134176.9178.3-63.7-171.2176.3-172.80111Y253 K254 Y271 I272Y253-K257 CarbonylContact C-O 3.57Å; Y253-K257 WeakPolarHBondContact CA-O 3.41Å; Y253-K257 WeakPolarHBondContact CD2-O 3.12Å; K254-K257 PolarHBondContact N-O 3.38Å; K254-K257 PolarHBondContact O-N 3.14Å; K254-K257 VanDerWaalsContact O-N 3.16Å; K257-Y271 HydrophobicContact CB-CD2 4.47Å; K257-I272 CarbonylContact C-O 3.58Å; K257-I272 WeakPolarHBondContact CA-O 2.87Å; K257-I272 WeakPolarHBondContact CB-O 3.45Å
258Y98.6Very high96.2Very high0 Ų048.1 Ų48.10%028%0.278CS..EExtended strand (participates in β ladder)trans-127.2137.5-176.4-62.7-86.4000111.5A249 F252 Y253 Y271 I272 P274 L277 F297 D298 D301A249-Y258 HydrophobicContact CB-CD1 4.13Å; A249-Y258 HydrophobicContact CB-CE1 3.85Å; F252-Y258 AromaticContact CD2-CD1 3.9Å; F252-Y258 HydrophobicContact CD2-CD1 3.9Å; F252-Y258 HydrophobicContact CD2-CG 4.4Å; F252-Y258 AromaticContact CE2-CD1 3.76Å; F252-Y258 HydrophobicContact CE2-CD1 3.76Å; F252-Y258 HydrophobicContact CE2-CG 4.23Å; F252-Y258 WeakPolarHBondContact O-CA 3.26Å; Y253-Y258 HydrophobicContact CD2-CD1 4.04Å; Y253-Y258 AromaticContact CD2-CE1 3.56Å; Y253-Y258 HydrophobicContact CD2-CE1 3.56Å; Y253-Y258 HydrophobicContact CD2-CE2 4.21Å; Y253-Y258 AromaticContact CD2-CZ 3.64Å; Y253-Y258 HydrophobicContact CE2-CE1 4.46Å; Y253-Y258 HydrophobicContact CE2-CE2 4.45Å; Y253-Y258 HydrophobicContact CG-CE1 4.25Å; Y258-Y271 WeakPolarHBondContact O-CA 3.19Å; Y258-I272 PolarHBondContact N-O 3.16Å; Y258-I272 PolarHBondContact O-N 2.54Å; Y258-P274 HydrophobicContact CE2-CB 4.04Å; Y258-P274 HydrophobicContact CE2-CG 3.9Å; Y258-L277 HydrophobicContact CD1-CD2 3.83Å; Y258-L277 HydrophobicContact CD2-CB 4.49Å; Y258-L277 HydrophobicContact CD2-CD2 3.63Å; Y258-L277 HydrophobicContact CE1-CD2 4.23Å; Y258-L277 HydrophobicContact CE2-CD2 4.07Å; Y258-L277 HydrophobicContact CG-CD2 3.51Å; Y258-F297 HydrophobicContact CE2-CD1 4.06Å; Y258-F297 AromaticContact CZ-CD1 3.96Å; Y258-F297 WeakPolarHBondContact OH-CB 3.47Å; Y258-D298 HydrophobicContact CE1-CB 4.23Å; Y258-D298 PolarHBondContact OH-N 2.81Å; Y258-D301 PolarHBondContact OH-OD2 3.38Å
259D98Very high96.2Very high1 Ų152.9 Ų52.91%0.00531%0.311CS..  trans-109.198.2179.7-174.64.3000112.4F252 K254 D261 F262 R270 Y271F252-D259 VanDerWaalsContact CB-O 3.29Å; F252-D259 WeakPolarHBondContact CB-O 3.49Å; F252-D259 PolarHBondContact O-N 3.11Å; K254-D259 HydrophobicContact CG-CB 4.1Å; D259-D261 PolarHBondContact O-N 2.88Å; D259-D261 VanDerWaalsContact O-N 3.08Å; D259-D261 PolarHBondContact OD1-N 2.78Å; D259-F262 HydrophobicContact CB-CB 4.06Å; D259-F262 WeakPolarHBondContact O-CB 3.35Å; D259-F262 PolarHBondContact O-N 2.93Å; D259-F262 PolarHBondContact OD1-N 2.89Å; D259-F262 VanDerWaalsContact OD2-CA 3.26Å; D259-F262 WeakPolarHBondContact OD2-CA 3.38Å; D259-F262 PolarHBondContact OD2-N 3.38Å; D259-R270 VanDerWaalsContact CG-NE 3.33Å; D259-R270 WeakPolarHBondContact OD1-CD 3.35Å; D259-R270 IonicContact OD1-CZ 2.62Å; D259-R270 IonicContact OD1-NE 2.87Å; D259-R270 PolarHBondContact OD1-NE 3.49Å; D259-R270 IonicContact OD1-NH2 3.72Å; D259-R270 IonicContact OD2-CZ 3.9Å; D259-R270 IonicContact OD2-NE 2.82Å; D259-R270 PolarHBondContact OD2-NE 2.96Å; D259-R270 IonicContact OD2-NH2 3.49Å; D259-R270 PolarHBondContact OD2-NH2 2.8Å; D259-Y271 HydrophobicContact CB-CD1 3.62Å; D259-Y271 HydrophobicContact CB-CE1 3.51Å; D259-Y271 VanDerWaalsContact CG-CE1 3.41Å; D259-Y271 VanDerWaalsContact OD2-CE1 3.31Å; D259-Y271 WeakPolarHBondContact OD2-CE1 3.44Å
260L97.3Very high96.1Very high35 Ų3555.9 Ų55.918%0.18332%0.322CS..THydrogen-bonded Turntrans-72.93.3179.1-61.7-178.2000114.7A165 M166 F252 I272 L277 L280A165-L260 HydrophobicContact CB-CB 4.37Å; A165-L260 HydrophobicContact CB-CD2 4.26Å; A165-L260 VanDerWaalsContact CB-O 3.23Å; A165-L260 WeakPolarHBondContact CB-O 3.38Å; M166-L260 HydrophobicContact CE-CD2 4.46Å; F252-L260 HydrophobicContact CD2-CD2 4.38Å; F252-L260 HydrophobicContact CE2-CD2 3.81Å; F252-L260 HydrophobicContact CZ-CD2 4.02Å; L260-I272 HydrophobicContact CD1-CD1 3.6Å; L260-I272 HydrophobicContact CG-CD1 3.97Å; L260-L277 HydrophobicContact CD1-CD1 4.47Å; L260-L277 HydrophobicContact CD2-CD1 4.11Å; L260-L280 HydrophobicContact CD1-CD2 3.57Å
261D96.1Very high96.1Very high29 Ų2956.2 Ų56.216%0.15532%0.32CS..THydrogen-bonded Turntrans-131.333172.2-175.132.8000110.9L219 D259 K263 S264 R270L219-D261 HydrophobicContact CD1-CB 3.98Å; L219-D261 WeakPolarHBondContact CD1-OD1 3.14Å; D259-D261 PolarHBondContact O-N 2.88Å; D259-D261 VanDerWaalsContact O-N 3.08Å; D259-D261 PolarHBondContact OD1-N 2.78Å; D261-K263 PolarHBondContact O-N 2.82Å; D261-S264 VanDerWaalsContact CG-CB 3.45Å; D261-S264 WeakPolarHBondContact O-CB 3.24Å; D261-S264 PolarHBondContact O-N 2.93Å; D261-S264 VanDerWaalsContact OD1-CB 3.28Å; D261-S264 WeakPolarHBondContact OD1-CB 3.25Å; D261-S264 PolarHBondContact OD1-OG 2.64Å; D261-S264 WeakPolarHBondContact OD2-CB 3.44Å; D261-S264 PolarHBondContact OD2-OG 3.06Å; D261-S264 VanDerWaalsContact OD2-OG 3.11Å; D261-R270 VanDerWaalsContact O-CZ 3.22Å; D261-R270 PolarHBondContact O-NH1 2.98Å; D261-R270 PolarHBondContact O-NH2 3.45Å; D261-R270 IonicContact OD2-CZ 2.72Å; D261-R270 IonicContact OD2-NH1 3.25Å; D261-R270 PolarHBondContact OD2-NH1 2.85Å
262F95.7Very high96.3Very high40 Ų4054.6 Ų54.618%0.17531%0.314CS..THydrogen-bonded Turntrans-56.9-15-175.480.1-82.5000116.2A165 F252 D259A165-F262 HydrophobicContact CB-CD1 4.02Å; A165-F262 HydrophobicContact CB-CE1 4.09Å; F252-F262 HydrophobicContact CB-CB 3.79Å; F252-F262 HydrophobicContact CB-CD1 3.51Å; F252-F262 HydrophobicContact CB-CD2 4.44Å; F252-F262 HydrophobicContact CB-CE1 4.14Å; F252-F262 HydrophobicContact CB-CG 3.67Å; F252-F262 HydrophobicContact CD1-CD1 4.27Å; F252-F262 HydrophobicContact CD1-CE1 4.2Å; F252-F262 HydrophobicContact CG-CD1 4.26Å; D259-F262 HydrophobicContact CB-CB 4.06Å; D259-F262 WeakPolarHBondContact O-CB 3.35Å; D259-F262 PolarHBondContact O-N 2.93Å; D259-F262 PolarHBondContact OD1-N 2.89Å; D259-F262 VanDerWaalsContact OD2-CA 3.26Å; D259-F262 WeakPolarHBondContact OD2-CA 3.38Å; D259-F262 PolarHBondContact OD2-N 3.38Å
263K94.1Very high96.4Very high68 Ų6856.8 Ų56.830%0.29633%0.327SS..THydrogen-bonded Turntrans-85.7-12175.9-68.5-174.6-78.3-174.50113.1G157 A160 N162 K163 L164 D261G157-K263 PolarHBondContact O-NZ 2.95Å; A160-K263 PolarHBondContact O-NZ 2.75Å; A160-K263 VanDerWaalsContact O-NZ 3.15Å; N162-K263 VanDerWaalsContact O-CD 3.3Å; N162-K263 WeakPolarHBondContact O-CD 3.33Å; N162-K263 WeakPolarHBondContact O-CE 3.12Å; N162-K263 PolarHBondContact O-NZ 2.66Å; N162-K263 PolarHBondContact OD1-NZ 2.69Å; K163-K263 WeakPolarHBondContact O-CE 3.43Å; L164-K263 WeakPolarHBondContact O-CE 3.3Å; L164-K263 PolarHBondContact O-NZ 3.17Å; D261-K263 PolarHBondContact O-N 2.82Å
264S93.9Very high96.4Very high16 Ų1654.4 Ų54.411%0.11232%0.322CS..SBendtrans-90.6163.5168-63.50000110K163 D261 D266 R270K163-S264 PolarHBondContact NZ-OG 2.68Å; K163-S264 VanDerWaalsContact NZ-OG 3.16Å; D261-S264 VanDerWaalsContact CG-CB 3.45Å; D261-S264 WeakPolarHBondContact O-CB 3.24Å; D261-S264 PolarHBondContact O-N 2.93Å; D261-S264 VanDerWaalsContact OD1-CB 3.28Å; D261-S264 WeakPolarHBondContact OD1-CB 3.25Å; D261-S264 PolarHBondContact OD1-OG 2.64Å; D261-S264 WeakPolarHBondContact OD2-CB 3.44Å; D261-S264 PolarHBondContact OD2-OG 3.06Å; D261-S264 VanDerWaalsContact OD2-OG 3.11Å; S264-D266 PolarHBondContact O-N 3.41Å; S264-R270 PolarHBondContact O-NH2 2.9Å
265P95.4Very high96.5Very high117 Ų11755.2 Ų55.276%0.7633%0.33SS*.SBendtrans-47.6139.9175.3-29.136000112.6D267 R270P265-D267 PolarHBondContact O-N 2.7Å; P265-R270 PolarHBondContact O-NH1 2.87Å; P265-R270 VanDerWaalsContact O-NH1 3.13Å; P265-R270 PolarHBondContact O-NH2 2.83Å
266D95.8Very high96.9Very high105 Ų10556.2 Ų56.256%0.56131%0.311SS*.PPolyproline II helixtrans-59.8127.3-172.8-156.377.8000111.3K254 S264 Y271K254-D266 IonicContact NZ-OD1 3.66Å; S264-D266 PolarHBondContact O-N 3.41Å; D266-Y271 PolarHBondContact OD1-OH 2.78Å; D266-Y271 PolarHBondContact OD2-OH 3.47Å
267D96.3Very high97Very high70 Ų7054.7 Ų54.737%0.37430%0.296SS..  trans-141.8100.4176.5-179-5.1000110.2P265 S269 R270 Y271P265-D267 PolarHBondContact O-N 2.7Å; D267-S269 VanDerWaalsContact CG-OG 3.24Å; D267-S269 PolarHBondContact O-N 2.77Å; D267-S269 VanDerWaalsContact OD1-CB 3.27Å; D267-S269 WeakPolarHBondContact OD1-CB 3.28Å; D267-S269 PolarHBondContact OD1-N 3.49Å; D267-S269 PolarHBondContact OD1-OG 2.82Å; D267-S269 PolarHBondContact OD2-OG 2.61Å; D267-R270 HydrophobicContact CB-CG 4.11Å; D267-R270 WeakPolarHBondContact O-CG 2.74Å; D267-R270 PolarHBondContact O-N 2.97Å; D267-Y271 WeakPolarHBondContact O-CD1 3.49Å; D267-Y271 WeakPolarHBondContact O-CE1 3.49Å
268P96.3Very high97.1Very high81 Ų8150.9 Ų50.953%0.52628%0.281SS..G310 helixtrans-61.7-15.6-179.4-26.535.8000115.5R270 Y271P268-R270 VanDerWaalsContact C-N 3.32Å; P268-Y271 HydrophobicContact CB-CD2 4.15Å; P268-Y271 HydrophobicContact CB-CE2 3.94Å; P268-Y271 HydrophobicContact CG-CE2 4.19Å; P268-Y271 PolarHBondContact O-N 3.12Å
269S96.7Very high97Very high101 Ų10155.3 Ų55.371%0.70631%0.305SS*.G310 helixtrans-73.2-23.5179.875.70000113.3D267D267-S269 VanDerWaalsContact CG-OG 3.24Å; D267-S269 PolarHBondContact O-N 2.77Å; D267-S269 VanDerWaalsContact OD1-CB 3.27Å; D267-S269 WeakPolarHBondContact OD1-CB 3.28Å; D267-S269 PolarHBondContact OD1-N 3.49Å; D267-S269 PolarHBondContact OD1-OG 2.82Å; D267-S269 PolarHBondContact OD2-OG 2.61Å
270R95.8Very high97.1Very high64 Ų6457.5 Ų57.524%0.24232%0.316CS..G310 helixtrans-87.2-4.517559.4167-166.7-132.1-9.5114D259 D261 S264 P265 D267 P268 I272D259-R270 VanDerWaalsContact CG-NE 3.33Å; D259-R270 WeakPolarHBondContact OD1-CD 3.35Å; D259-R270 IonicContact OD1-CZ 2.62Å; D259-R270 IonicContact OD1-NE 2.87Å; D259-R270 PolarHBondContact OD1-NE 3.49Å; D259-R270 IonicContact OD1-NH2 3.72Å; D259-R270 IonicContact OD2-CZ 3.9Å; D259-R270 IonicContact OD2-NE 2.82Å; D259-R270 PolarHBondContact OD2-NE 2.96Å; D259-R270 IonicContact OD2-NH2 3.49Å; D259-R270 PolarHBondContact OD2-NH2 2.8Å; D261-R270 VanDerWaalsContact O-CZ 3.22Å; D261-R270 PolarHBondContact O-NH1 2.98Å; D261-R270 PolarHBondContact O-NH2 3.45Å; D261-R270 IonicContact OD2-CZ 2.72Å; D261-R270 IonicContact OD2-NH1 3.25Å; D261-R270 PolarHBondContact OD2-NH1 2.85Å; S264-R270 PolarHBondContact O-NH2 2.9Å; P265-R270 PolarHBondContact O-NH1 2.87Å; P265-R270 VanDerWaalsContact O-NH1 3.13Å; P265-R270 PolarHBondContact O-NH2 2.83Å; D267-R270 HydrophobicContact CB-CG 4.11Å; D267-R270 WeakPolarHBondContact O-CG 2.74Å; D267-R270 PolarHBondContact O-N 2.97Å; P268-R270 VanDerWaalsContact C-N 3.32Å; R270-I272 PolarHBondContact O-N 2.84Å
271Y98.1Very high97.1Very high25 Ų2555.9 Ų55.910%0.09831%0.308CS..PPolyproline II helixtrans-70.7131-177.3-62.9-4.2000111.4K254 K257 Y258 D259 D266 D267 P268K254-Y271 HydrophobicContact CB-CD2 3.81Å; K254-Y271 HydrophobicContact CB-CE2 3.45Å; K254-Y271 VanDerWaalsContact CB-CE2 3.45Å; K254-Y271 HydrophobicContact CG-CD2 4.49Å; K254-Y271 HydrophobicContact CG-CE1 4.36Å; K254-Y271 HydrophobicContact CG-CE2 3.9Å; K257-Y271 HydrophobicContact CB-CD2 4.47Å; Y258-Y271 WeakPolarHBondContact O-CA 3.19Å; D259-Y271 HydrophobicContact CB-CD1 3.62Å; D259-Y271 HydrophobicContact CB-CE1 3.51Å; D259-Y271 VanDerWaalsContact CG-CE1 3.41Å; D259-Y271 VanDerWaalsContact OD2-CE1 3.31Å; D259-Y271 WeakPolarHBondContact OD2-CE1 3.44Å; D266-Y271 PolarHBondContact OD1-OH 2.78Å; D266-Y271 PolarHBondContact OD2-OH 3.47Å; D267-Y271 WeakPolarHBondContact O-CD1 3.49Å; D267-Y271 WeakPolarHBondContact O-CE1 3.49Å; P268-Y271 HydrophobicContact CB-CD2 4.15Å; P268-Y271 HydrophobicContact CB-CE2 3.94Å; P268-Y271 HydrophobicContact CG-CE2 4.19Å; P268-Y271 PolarHBondContact O-N 3.12Å
272I98.5Very high97.2Very high36 Ų3658.3 Ų58.319%0.18532%0.317CS..BIsolated β-bridgetrans-103.4150.2-179.863172.5000111.4K257 Y258 L260 R270 Q276 L277K257-I272 CarbonylContact C-O 3.58Å; K257-I272 WeakPolarHBondContact CA-O 2.87Å; K257-I272 WeakPolarHBondContact CB-O 3.45Å; Y258-I272 PolarHBondContact N-O 3.16Å; Y258-I272 PolarHBondContact O-N 2.54Å; L260-I272 HydrophobicContact CD1-CD1 3.6Å; L260-I272 HydrophobicContact CG-CD1 3.97Å; R270-I272 PolarHBondContact O-N 2.84Å; I272-Q276 HydrophobicContact CB-CB 3.96Å; I272-L277 HydrophobicContact CD1-CB 3.91Å; I272-L277 HydrophobicContact CD1-CD1 3.92Å; I272-L277 HydrophobicContact CD1-CG 4.48Å; I272-L277 HydrophobicContact CG1-CB 4.41Å
273T98.6Very high97.4Very high47 Ų4758.3 Ų58.329%0.28832%0.322SS..PPolyproline II helixtrans-74.6163.6177.766.90000111.4D275 Q276 L277T273-D275 PolarHBondContact O-N 3.27Å; T273-Q276 PolarHBondContact O-N 3.07Å; T273-Q276 WeakPolarHBondContact OG1-CG 3.34Å; T273-Q276 PolarHBondContact OG1-N 3.03Å; T273-Q276 PolarHBondContact OG1-OE1 3.01Å; T273-L277 PolarHBondContact O-N 2.88Å
274P98.6Very high97.6Very high29 Ų2955.2 Ų55.219%0.18831%0.308CS..Hα-helixtrans-54.7-39.1172.2-19.125.4000112.8Y258 L277 A278 F297 A304Y258-P274 HydrophobicContact CE2-CB 4.04Å; Y258-P274 HydrophobicContact CE2-CG 3.9Å; P274-L277 PolarHBondContact O-N 3Å; P274-A278 WeakPolarHBondContact O-CB 3.42Å; P274-A278 PolarHBondContact O-N 2.8Å; P274-F297 HydrophobicContact CB-CD1 4.29Å; P274-F297 HydrophobicContact CB-CE1 4.23Å; P274-F297 WeakPolarHBondContact O-CE1 3.42Å; P274-A304 HydrophobicContact CB-CB 3.65Å; P274-A304 HydrophobicContact CG-CB 4.46Å
275D98.6Very high97.8Very high93 Ų9356.5 Ų56.550%0.49732%0.315SS..Hα-helixtrans-65.6-42.1178.3-68.2-27.4000112.3T273 L277 A278 D279T273-D275 PolarHBondContact O-N 3.27Å; D275-L277 VanDerWaalsContact C-N 3.32Å; D275-L277 PolarHBondContact O-N 3.24Å; D275-A278 WeakPolarHBondContact O-CB 3.37Å; D275-A278 PolarHBondContact O-N 2.98Å; D275-D279 PolarHBondContact O-N 2.91Å
276Q98.6Very high97.9Very high104 Ų10459.4 Ų59.449%0.48632%0.316SS..Hα-helixtrans-64.5-38.7176-73.3174.2-46.300111.7I272 T273 D279 L280I272-Q276 HydrophobicContact CB-CB 3.96Å; T273-Q276 PolarHBondContact O-N 3.07Å; T273-Q276 WeakPolarHBondContact OG1-CG 3.34Å; T273-Q276 PolarHBondContact OG1-N 3.03Å; T273-Q276 PolarHBondContact OG1-OE1 3.01Å; Q276-D279 PolarHBondContact O-N 3.09Å; Q276-L280 PolarHBondContact O-N 3.03Å
277L98.6Very high97.9Very high0 Ų057.8 Ų57.80%031%0.307CS..Hα-helixtrans-67.5-41175.6-176.560000111.4F252 Y258 L260 I272 T273 P274 D275 D279 L280 Y281 P296 F297F252-L277 HydrophobicContact CE2-CD2 4.39Å; Y258-L277 HydrophobicContact CD1-CD2 3.83Å; Y258-L277 HydrophobicContact CD2-CB 4.49Å; Y258-L277 HydrophobicContact CD2-CD2 3.63Å; Y258-L277 HydrophobicContact CE1-CD2 4.23Å; Y258-L277 HydrophobicContact CE2-CD2 4.07Å; Y258-L277 HydrophobicContact CG-CD2 3.51Å; L260-L277 HydrophobicContact CD1-CD1 4.47Å; L260-L277 HydrophobicContact CD2-CD1 4.11Å; I272-L277 HydrophobicContact CD1-CB 3.91Å; I272-L277 HydrophobicContact CD1-CD1 3.92Å; I272-L277 HydrophobicContact CD1-CG 4.48Å; I272-L277 HydrophobicContact CG1-CB 4.41Å; T273-L277 PolarHBondContact O-N 2.88Å; P274-L277 PolarHBondContact O-N 3Å; D275-L277 VanDerWaalsContact C-N 3.32Å; D275-L277 PolarHBondContact O-N 3.24Å; L277-D279 VanDerWaalsContact C-N 3.33Å; L277-D279 PolarHBondContact O-N 3.17Å; L277-L280 HydrophobicContact CD1-CD2 4.38Å; L277-L280 WeakPolarHBondContact O-CB 3.47Å; L277-L280 PolarHBondContact O-N 3.32Å; L277-Y281 HydrophobicContact CD1-CE1 4.02Å; L277-Y281 HydrophobicContact CD1-CE2 4.04Å; L277-Y281 WeakPolarHBondContact CD1-OH 3.17Å; L277-Y281 HydrophobicContact CD2-CE2 4.13Å; L277-Y281 WeakPolarHBondContact CD2-OH 3.43Å; L277-Y281 HydrophobicContact CG-CD2 4.42Å; L277-Y281 HydrophobicContact CG-CE1 4.43Å; L277-Y281 HydrophobicContact CG-CE2 3.53Å; L277-Y281 WeakPolarHBondContact CG-OH 3.36Å; L277-Y281 VanDerWaalsContact O-CD2 3.27Å; L277-Y281 WeakPolarHBondContact O-CD2 3.31Å; L277-Y281 PolarHBondContact O-N 3.05Å; L277-P296 WeakPolarHBondContact CD2-O 3.47Å; L277-F297 HydrophobicContact CB-CE1 4.31Å; L277-F297 HydrophobicContact CD2-CD1 4.15Å; L277-F297 HydrophobicContact CD2-CE1 4.15Å; L277-F297 HydrophobicContact CG-CE1 4.29Å
278A98.6Very high98Very high8 Ų854.9 Ų54.97%0.06629%0.291CS..Hα-helixtrans-59.5-42.6173.700000112.1P274 D275 L280 Y281 K282 F297 F308P274-A278 WeakPolarHBondContact O-CB 3.42Å; P274-A278 PolarHBondContact O-N 2.8Å; D275-A278 WeakPolarHBondContact O-CB 3.37Å; D275-A278 PolarHBondContact O-N 2.98Å; A278-L280 VanDerWaalsContact C-N 3.34Å; A278-Y281 PolarHBondContact O-N 2.91Å; A278-K282 WeakPolarHBondContact O-CG 3.43Å; A278-K282 PolarHBondContact O-N 3.24Å; A278-F297 HydrophobicContact CB-CE1 4.47Å; A278-F297 HydrophobicContact CB-CZ 3.91Å; A278-F308 HydrophobicContact CB-CD2 4.02Å
279D98.5Very high98.1Very high92 Ų9253.9 Ų53.949%0.49229%0.285SS..Hα-helixtrans-67.6-34.4177.7-74-15.1000112.3D275 Q276 L277 K282 S283D275-D279 PolarHBondContact O-N 2.91Å; Q276-D279 PolarHBondContact O-N 3.09Å; L277-D279 VanDerWaalsContact C-N 3.33Å; L277-D279 PolarHBondContact O-N 3.17Å; D279-K282 PolarHBondContact O-N 2.98Å; D279-K282 IonicContact OD1-NZ 3.78Å; D279-K282 PolarHBondContact OD1-NZ 2.87Å; D279-S283 PolarHBondContact O-N 3.27Å
280L98.4Very high98.2Very high48 Ų4849.3 Ų49.325%0.25125%0.252SS..Hα-helixtrans-60.2-47.2169.8-177.264.3000111.1M166 L260 Q276 L277 A278 K282 S283 F284M166-L280 HydrophobicContact CE-CD2 4.25Å; L260-L280 HydrophobicContact CD1-CD2 3.57Å; Q276-L280 PolarHBondContact O-N 3.03Å; L277-L280 HydrophobicContact CD1-CD2 4.38Å; L277-L280 WeakPolarHBondContact O-CB 3.47Å; L277-L280 PolarHBondContact O-N 3.32Å; A278-L280 VanDerWaalsContact C-N 3.34Å; L280-K282 PolarHBondContact O-N 2.99Å; L280-S283 WeakPolarHBondContact O-CB 3.31Å; L280-S283 PolarHBondContact O-N 3.27Å; L280-S283 VanDerWaalsContact O-N 3.14Å; L280-S283 PolarHBondContact O-OG 3.39Å; L280-F284 HydrophobicContact CD1-CD1 4.49Å; L280-F284 HydrophobicContact CD1-CE1 3.62Å; L280-F284 HydrophobicContact CD1-CE2 4.43Å; L280-F284 HydrophobicContact CD1-CZ 3.58Å; L280-F284 HydrophobicContact CD2-CE2 4.36Å; L280-F284 HydrophobicContact CD2-CZ 4.03Å; L280-F284 HydrophobicContact CG-CE1 4.06Å; L280-F284 HydrophobicContact CG-CE2 4Å; L280-F284 HydrophobicContact CG-CZ 3.61Å; L280-F284 PolarHBondContact O-N 3.06Å; L280-F284 VanDerWaalsContact O-N 3.09Å
281Y98.6Very high98.3Very high0 Ų048 Ų480%025%0.252CS..Hα-helixtrans-61.8-42.2176.4-59.6-41.9000112.9M166 V247 L277 A278 S283 F284 V285 I293 P296 F297 F308M166-Y281 HydrophobicContact CE-CD1 4.29Å; M166-Y281 HydrophobicContact CE-CE1 3.53Å; M166-Y281 HydrophobicContact SD-CE1 4.37Å; V247-Y281 HydrophobicContact CG1-CE1 4.25Å; V247-Y281 WeakPolarHBondContact CG1-OH 3.46Å; V247-Y281 HydrophobicContact CG2-CE1 3.76Å; L277-Y281 HydrophobicContact CD1-CE1 4.02Å; L277-Y281 HydrophobicContact CD1-CE2 4.04Å; L277-Y281 WeakPolarHBondContact CD1-OH 3.17Å; L277-Y281 HydrophobicContact CD2-CE2 4.13Å; L277-Y281 WeakPolarHBondContact CD2-OH 3.43Å; L277-Y281 HydrophobicContact CG-CD2 4.42Å; L277-Y281 HydrophobicContact CG-CE1 4.43Å; L277-Y281 HydrophobicContact CG-CE2 3.53Å; L277-Y281 WeakPolarHBondContact CG-OH 3.36Å; L277-Y281 VanDerWaalsContact O-CD2 3.27Å; L277-Y281 WeakPolarHBondContact O-CD2 3.31Å; L277-Y281 PolarHBondContact O-N 3.05Å; A278-Y281 PolarHBondContact O-N 2.91Å; Y281-S283 PolarHBondContact O-N 3.04Å; Y281-F284 HydrophobicContact CD1-CD2 4.43Å; Y281-F284 WeakPolarHBondContact O-CB 3.45Å; Y281-F284 PolarHBondContact O-N 3.06Å; Y281-V285 WeakPolarHBondContact O-CG2 3.46Å; Y281-V285 PolarHBondContact O-N 3.41Å; Y281-I293 HydrophobicContact CD1-CD1 4.39Å; Y281-I293 HydrophobicContact CG-CD1 4.28Å; Y281-P296 HydrophobicContact CD2-CB 4.01Å; Y281-P296 HydrophobicContact CE2-CB 3.47Å; Y281-P296 VanDerWaalsContact CE2-CB 3.47Å; Y281-P296 WeakPolarHBondContact CE2-O 3.49Å; Y281-P296 PolarHBondContact OH-O 3.3Å; Y281-F297 HydrophobicContact CD2-CZ 4.31Å; Y281-F297 HydrophobicContact CE2-CE1 4.28Å; Y281-F297 HydrophobicContact CE2-CZ 4.08Å; Y281-F308 HydrophobicContact CD2-CE2 4.13Å; Y281-F308 HydrophobicContact CD2-CZ 4.13Å; Y281-F308 HydrophobicContact CG-CE2 4.43Å; Y281-F308 HydrophobicContact CG-CZ 4.32Å
282K98.3Very high98.4Very high81 Ų8147 Ų4735%0.35225%0.248SC..Hα-helixtrans-59.3-37.9175.2-69.1171.2-158.7155.90111.4A278 D279 L280 F284 V285 K286 F308 T311A278-K282 WeakPolarHBondContact O-CG 3.43Å; A278-K282 PolarHBondContact O-N 3.24Å; D279-K282 PolarHBondContact O-N 2.98Å; D279-K282 IonicContact OD1-NZ 3.78Å; D279-K282 PolarHBondContact OD1-NZ 2.87Å; L280-K282 PolarHBondContact O-N 2.99Å; K282-F284 VanDerWaalsContact C-N 3.32Å; K282-F284 PolarHBondContact O-N 3.41Å; K282-V285 PolarHBondContact O-N 3.17Å; K282-K286 WeakPolarHBondContact O-CB 3.19Å; K282-K286 PolarHBondContact O-N 3.42Å; K282-F308 HydrophobicContact CG-CE2 4.44Å; K282-T311 WeakPolarHBondContact CE-OG1 3.5Å
283S98.1Very high98.4Very high40 Ų4045.2 Ų45.228%0.2824%0.239SC..Hα-helixtrans-62.9-39.1174850000111.8D279 L280 Y281 K286 D287D279-S283 PolarHBondContact O-N 3.27Å; L280-S283 WeakPolarHBondContact O-CB 3.31Å; L280-S283 PolarHBondContact O-N 3.27Å; L280-S283 VanDerWaalsContact O-N 3.14Å; L280-S283 PolarHBondContact O-OG 3.39Å; Y281-S283 PolarHBondContact O-N 3.04Å; S283-K286 PolarHBondContact O-N 3.24Å; S283-D287 WeakPolarHBondContact O-CB 3.5Å; S283-D287 PolarHBondContact O-N 3.45Å
284F98.4Very high98.4Very high3 Ų343 Ų431%0.01323%0.226CC..Hα-helixtrans-67.4-43.8177.2-62.7-14.7000112.3M166 N221 K222 L225 M245 L280 Y281 K282 K286 D287 Y288M166-F284 HydrophobicContact CE-CE2 3.84Å; M166-F284 HydrophobicContact SD-CE2 4.07Å; N221-F284 HydrophobicContact CB-CE2 3.97Å; N221-F284 HydrophobicContact CB-CZ 3.85Å; K222-F284 HydrophobicContact CB-CE1 4.16Å; L225-F284 HydrophobicContact CD1-CB 3.83Å; L225-F284 HydrophobicContact CD1-CD1 3.83Å; L225-F284 HydrophobicContact CD1-CD2 3.82Å; L225-F284 HydrophobicContact CD1-CE1 4.33Å; L225-F284 HydrophobicContact CD1-CE2 4.31Å; L225-F284 HydrophobicContact CD1-CG 3.56Å; M245-F284 HydrophobicContact CE-CD2 3.93Å; M245-F284 HydrophobicContact CE-CE2 4.15Å; M245-F284 HydrophobicContact SD-CD2 4.2Å; L280-F284 HydrophobicContact CD1-CD1 4.49Å; L280-F284 HydrophobicContact CD1-CE1 3.62Å; L280-F284 HydrophobicContact CD1-CE2 4.43Å; L280-F284 HydrophobicContact CD1-CZ 3.58Å; L280-F284 HydrophobicContact CD2-CE2 4.36Å; L280-F284 HydrophobicContact CD2-CZ 4.03Å; L280-F284 HydrophobicContact CG-CE1 4.06Å; L280-F284 HydrophobicContact CG-CE2 4Å; L280-F284 HydrophobicContact CG-CZ 3.61Å; L280-F284 PolarHBondContact O-N 3.06Å; L280-F284 VanDerWaalsContact O-N 3.09Å; Y281-F284 HydrophobicContact CD1-CD2 4.43Å; Y281-F284 WeakPolarHBondContact O-CB 3.45Å; Y281-F284 PolarHBondContact O-N 3.06Å; K282-F284 VanDerWaalsContact C-N 3.32Å; K282-F284 PolarHBondContact O-N 3.41Å; F284-K286 PolarHBondContact O-N 2.86Å; F284-D287 PolarHBondContact O-N 3.01Å; F284-Y288 HydrophobicContact CB-CD2 4.44Å; F284-Y288 HydrophobicContact CD1-CE2 4.46Å; F284-Y288 WeakPolarHBondContact O-CB 3.36Å; F284-Y288 WeakPolarHBondContact O-CD2 3.49Å; F284-Y288 PolarHBondContact O-N 3.15Å
285V98.1Very high98.4Very high42 Ų4241.8 Ų41.826%0.25522%0.217SC..Hα-helixtrans-63.5-31.9176.5175.10000111.8Y281 K282 V290 I293 I314Y281-V285 WeakPolarHBondContact O-CG2 3.46Å; Y281-V285 PolarHBondContact O-N 3.41Å; K282-V285 PolarHBondContact O-N 3.17Å; V285-V290 HydrophobicContact CG2-CB 4.31Å; V285-V290 HydrophobicContact CG2-CG1 4.26Å; V285-I293 HydrophobicContact CG2-CD1 4.18Å; V285-I314 HydrophobicContact CG1-CG2 3.77Å; V285-I314 HydrophobicContact CG2-CD1 3.71Å; V285-I314 HydrophobicContact CG2-CG2 4.32Å
286K97.5Very high98.4Very high178 Ų17837.3 Ų37.377%0.77419%0.193SC*.Hα-helixtrans-73.5-44.2176.4-178.4-174.2173.1-171.90112.4K282 S283 F284K282-K286 WeakPolarHBondContact O-CB 3.19Å; K282-K286 PolarHBondContact O-N 3.42Å; S283-K286 PolarHBondContact O-N 3.24Å; F284-K286 PolarHBondContact O-N 2.86Å
287D97.6Very high98.4Very high71 Ų7132.4 Ų32.438%0.3817%0.17SC..Hα-helixtrans-91.1-18.7-169-68.6-5.8000113.2K222 S283 F284K222-D287 IonicContact NZ-OD2 3.29Å; S283-D287 WeakPolarHBondContact O-CB 3.5Å; S283-D287 PolarHBondContact O-N 3.45Å; F284-D287 PolarHBondContact O-N 3.01Å
288Y98.2Very high98.4Very high10 Ų1033.2 Ų33.24%0.03918%0.175CC..SBendtrans-134.6157.6-175.6-54.3-80.3000111.4K222 L225 E226 K229 F284 V290K222-Y288 WeakPolarHBondContact CE-OH 3.36Å; K222-Y288 HydrophobicContact CG-CE2 4.15Å; K222-Y288 WeakPolarHBondContact CG-OH 3.49Å; L225-Y288 HydrophobicContact CB-CD1 3.81Å; L225-Y288 HydrophobicContact CB-CD2 3.96Å; L225-Y288 HydrophobicContact CB-CE1 3.8Å; L225-Y288 HydrophobicContact CB-CE2 3.94Å; L225-Y288 HydrophobicContact CB-CG 3.9Å; L225-Y288 HydrophobicContact CD1-CD2 3.56Å; L225-Y288 HydrophobicContact CD1-CE2 3.83Å; L225-Y288 HydrophobicContact CD1-CG 4.11Å; L225-Y288 HydrophobicContact CG-CD2 4.31Å; L225-Y288 HydrophobicContact CG-CG 4.46Å; E226-Y288 HydrophobicContact CG-CE1 4.2Å; E226-Y288 WeakPolarHBondContact CG-OH 3.23Å; E226-Y288 WeakPolarHBondContact OE1-CE1 3.17Å; E226-Y288 VanDerWaalsContact OE1-CZ 3.24Å; E226-Y288 PolarHBondContact OE1-OH 2.64Å; K229-Y288 HydrophobicContact CD-CD1 4.27Å; K229-Y288 HydrophobicContact CD-CE1 4.23Å; F284-Y288 HydrophobicContact CB-CD2 4.44Å; F284-Y288 HydrophobicContact CD1-CE2 4.46Å; F284-Y288 WeakPolarHBondContact O-CB 3.36Å; F284-Y288 WeakPolarHBondContact O-CD2 3.49Å; F284-Y288 PolarHBondContact O-N 3.15Å; Y288-V290 PolarHBondContact O-N 3.31Å
289P97.6Very high98.3Very high60 Ų6033.9 Ų33.939%0.3918%0.177SC..  trans-76.248.6178.734.5-37.9000112.2V242 I243 V291V242-P289 WeakPolarHBondContact CB-O 3.21Å; V242-P289 HydrophobicContact CG1-CB 4.49Å; I243-P289 HydrophobicContact CD1-CG 4.26Å; I243-P289 HydrophobicContact CG1-CG 4.35Å; I243-P289 PolarHBondContact N-O 2.95Å; P289-V291 PolarHBondContact O-N 3.05Å
290V98.7Very high98.3Very high4 Ų432.6 Ų32.62%0.02417%0.169CC..EExtended strand (participates in β ladder)trans-76.7120.6177177.40000109L225 I243 M245 V285 Y288 I293L225-V290 HydrophobicContact CD2-CG2 4.09Å; I243-V290 HydrophobicContact CB-CG2 4.11Å; I243-V290 HydrophobicContact CG2-CG2 3.98Å; I243-V290 CarbonylContact O-C 3.57Å; I243-V290 WeakPolarHBondContact O-CA 3.31Å; M245-V290 HydrophobicContact CG-CG1 4.46Å; M245-V290 HydrophobicContact SD-CG1 4.15Å; M245-V290 HydrophobicContact SD-CG2 4.05Å; V285-V290 HydrophobicContact CG2-CB 4.31Å; V285-V290 HydrophobicContact CG2-CG1 4.26Å; Y288-V290 PolarHBondContact O-N 3.31Å; V290-I293 HydrophobicContact CG1-CD1 4.09Å; V290-I293 HydrophobicContact CG1-CG1 3.77Å
291V98.7Very high98.3Very high38 Ų3831.5 Ų31.523%0.2316%0.164CC..EExtended strand (participates in β ladder)trans-121-6.7-177.3-59.10000113.7V242 I243 P289 I314 Q315 F429V242-V291 HydrophobicContact CB-CB 4.43Å; V242-V291 HydrophobicContact CB-CG1 3.81Å; V242-V291 HydrophobicContact CB-CG2 3.75Å; V242-V291 HydrophobicContact CG1-CG1 3.93Å; V242-V291 HydrophobicContact CG2-CB 4.4Å; V242-V291 HydrophobicContact CG2-CG1 4.2Å; V242-V291 HydrophobicContact CG2-CG2 3.34Å; I243-V291 PolarHBondContact O-N 3.49Å; P289-V291 PolarHBondContact O-N 3.05Å; V291-I314 WeakPolarHBondContact O-CB 3.38Å; V291-Q315 WeakPolarHBondContact O-CB 3.1Å; V291-Q315 PolarHBondContact O-N 3.07Å; V291-F429 HydrophobicContact CG2-CE1 4.5Å; V291-F429 HydrophobicContact CG2-CZ 4.12Å
292S98.9Very high98.3Very high2 Ų233.1 Ų33.11%0.01417%0.17CC..EExtended strand (participates in β ladder)trans-145.9129.5178.9-168.70000110.3G244 M245 Q315 V317G244-S292 CarbonylContact C-O 3.59Å; G244-S292 VanDerWaalsContact CA-O 3.3Å; G244-S292 WeakPolarHBondContact CA-O 3.46Å; M245-S292 PolarHBondContact N-O 2.66Å; S292-Q315 CarbonylContact C-O 3.59Å; S292-Q315 VanDerWaalsContact CA-O 3.28Å; S292-Q315 WeakPolarHBondContact CA-O 3.37Å; S292-Q315 PolarHBondContact OG-NE2 3.1Å; S292-V317 WeakPolarHBondContact OG-CG2 3.41Å
293I98.9Very high98.3Very high0 Ų035.1 Ų35.10%018%0.181CC..EExtended strand (participates in β ladder)trans-127.6122.9171.5-62.5175.3000108.2M245 V247 Y281 V285 V290 P296 F308 I314 Q315 V316 V317M245-I293 CarbonylContact O-C 3.59Å; M245-I293 WeakPolarHBondContact O-CA 3.34Å; V247-I293 HydrophobicContact CG2-CG2 3.75Å; Y281-I293 HydrophobicContact CD1-CD1 4.39Å; Y281-I293 HydrophobicContact CG-CD1 4.28Å; V285-I293 HydrophobicContact CG2-CD1 4.18Å; V290-I293 HydrophobicContact CG1-CD1 4.09Å; V290-I293 HydrophobicContact CG1-CG1 3.77Å; I293-P296 HydrophobicContact CG2-CB 3.9Å; I293-P296 HydrophobicContact CG2-CG 4.4Å; I293-F308 HydrophobicContact CD1-CZ 4.17Å; I293-I314 HydrophobicContact CB-CD1 4.23Å; I293-I314 HydrophobicContact CD1-CD1 3.67Å; I293-I314 HydrophobicContact CG1-CD1 3.68Å; I293-Q315 PolarHBondContact N-O 2.99Å; I293-V316 CarbonylContact O-C 3.44Å; I293-V316 WeakPolarHBondContact O-CA 3.25Å; I293-V317 PolarHBondContact O-N 3.26Å
294E98.9Very high98.3Very high1 Ų133.5 Ų33.51%0.00517%0.17CC..EExtended strand (participates in β ladder)trans-100.6139.2176.3177.5-179134.100109.7M245 D246 V247 P296 V317 D319 L342 K395M245-E294 WeakPolarHBondContact O-CB 3.39Å; M245-E294 PolarHBondContact O-N 3.18Å; D246-E294 HydrophobicContact CB-CB 4Å; D246-E294 HydrophobicContact CB-CG 4.12Å; D246-E294 VanDerWaalsContact CG-OE1 3.27Å; V247-E294 PolarHBondContact N-O 2.52Å; E294-P296 VanDerWaalsContact C-CD 3.47Å; E294-V317 WeakPolarHBondContact CA-O 3.44Å; E294-V317 HydrophobicContact CB-CB 3.8Å; E294-V317 HydrophobicContact CB-CG1 4.42Å; E294-V317 HydrophobicContact CB-CG2 4.34Å; E294-V317 HydrophobicContact CG-CB 4.06Å; E294-V317 HydrophobicContact CG-CG1 4.2Å; E294-D319 HydrophobicContact CG-CB 3.98Å; E294-L342 WeakPolarHBondContact OE1-CD2 3.44Å; E294-L342 WeakPolarHBondContact OE2-CD1 3.35Å; E294-K395 IonicContact OE1-NZ 3.76Å; E294-K395 PolarHBondContact OE1-NZ 3.04Å; E294-K395 IonicContact OE2-NZ 3.57Å; E294-K395 PolarHBondContact OE2-NZ 3.43Å
295D98.5Very high98.3Very high2 Ų233.3 Ų33.31%0.01117%0.169CC..  trans42.953.4-180-72-2.8000116.1V247 A249 F297 W305 V317 D319 D320V247-D295 WeakPolarHBondContact CB-O 3.5Å; A249-D295 VanDerWaalsContact CB-O 3.25Å; A249-D295 WeakPolarHBondContact CB-O 3.26Å; A249-D295 PolarHBondContact N-O 3.36Å; A249-D295 VanDerWaalsContact N-O 3.08Å; D295-F297 PolarHBondContact O-N 2.93Å; D295-F297 VanDerWaalsContact O-N 3.16Å; D295-W305 HydrophobicContact CB-CH2 4.4Å; D295-W305 HydrophobicContact CB-CZ2 4.32Å; D295-W305 VanDerWaalsContact OD1-CH2 3.23Å; D295-W305 WeakPolarHBondContact OD1-CH2 3.17Å; D295-W305 WeakPolarHBondContact OD1-CZ2 3.31Å; D295-V317 PolarHBondContact N-O 3.49Å; D295-V317 VanDerWaalsContact N-O 3.12Å; D295-D319 PolarHBondContact OD1-N 3.33Å; D295-D319 WeakPolarHBondContact OD2-CB 3.3Å; D295-D320 PolarHBondContact OD1-N 3.45Å; D295-D320 VanDerWaalsContact OD2-CB 3.31Å; D295-D320 WeakPolarHBondContact OD2-CB 3.36Å; D295-D320 PolarHBondContact OD2-N 2.94Å
296P98.7Very high98.3Very high0 Ų033.5 Ų33.50%017%0.17CC..  trans-62.6-19.2178.626.8-36.5000114.3L277 Y281 I293 E294 W305 F308 V316L277-P296 WeakPolarHBondContact CD2-O 3.47Å; Y281-P296 HydrophobicContact CD2-CB 4.01Å; Y281-P296 HydrophobicContact CE2-CB 3.47Å; Y281-P296 VanDerWaalsContact CE2-CB 3.47Å; Y281-P296 WeakPolarHBondContact CE2-O 3.49Å; Y281-P296 PolarHBondContact OH-O 3.3Å; I293-P296 HydrophobicContact CG2-CB 3.9Å; I293-P296 HydrophobicContact CG2-CG 4.4Å; E294-P296 VanDerWaalsContact C-CD 3.47Å; P296-W305 HydrophobicContact CG-CD2 4.44Å; P296-W305 HydrophobicContact CG-CE3 4.08Å; P296-W305 HydrophobicContact CG-CH2 4.3Å; P296-W305 HydrophobicContact CG-CZ3 4.04Å; P296-F308 HydrophobicContact CB-CD1 4.37Å; P296-F308 HydrophobicContact CB-CE1 4.34Å; P296-F308 HydrophobicContact CG-CD1 4.16Å; P296-F308 HydrophobicContact CG-CE1 4.34Å; P296-V316 HydrophobicContact CG-CG1 4.12Å
297F98.8Very high98.4Very high1 Ų129.6 Ų29.60%0.00415%0.153CC..SBendtrans-139.8167.5-179.6-56.2-73.7000110.1Y258 P274 L277 A278 Y281 D295 D301 A304 W305 F308Y258-F297 HydrophobicContact CE2-CD1 4.06Å; Y258-F297 AromaticContact CZ-CD1 3.96Å; Y258-F297 WeakPolarHBondContact OH-CB 3.47Å; P274-F297 HydrophobicContact CB-CD1 4.29Å; P274-F297 HydrophobicContact CB-CE1 4.23Å; P274-F297 WeakPolarHBondContact O-CE1 3.42Å; L277-F297 HydrophobicContact CB-CE1 4.31Å; L277-F297 HydrophobicContact CD2-CD1 4.15Å; L277-F297 HydrophobicContact CD2-CE1 4.15Å; L277-F297 HydrophobicContact CG-CE1 4.29Å; A278-F297 HydrophobicContact CB-CE1 4.47Å; A278-F297 HydrophobicContact CB-CZ 3.91Å; Y281-F297 HydrophobicContact CD2-CZ 4.31Å; Y281-F297 HydrophobicContact CE2-CE1 4.28Å; Y281-F297 HydrophobicContact CE2-CZ 4.08Å; D295-F297 PolarHBondContact O-N 2.93Å; D295-F297 VanDerWaalsContact O-N 3.16Å; F297-D301 HydrophobicContact CB-CB 4.28Å; F297-A304 HydrophobicContact CB-CB 4.08Å; F297-A304 HydrophobicContact CD1-CB 3.59Å; F297-A304 HydrophobicContact CD2-CB 3.9Å; F297-A304 HydrophobicContact CE1-CB 3.99Å; F297-A304 HydrophobicContact CE2-CB 4.3Å; F297-A304 HydrophobicContact CG-CB 3.54Å; F297-A304 HydrophobicContact CZ-CB 4.33Å; F297-W305 HydrophobicContact CB-CG 4.32Å; F297-W305 HydrophobicContact CD2-CD2 4.48Å; F297-W305 HydrophobicContact CD2-CG 4.25Å; F297-W305 PolarHBondContact O-NE1 3.25Å; F297-F308 HydrophobicContact CD2-CB 4.48Å; F297-F308 HydrophobicContact CE2-CB 3.37Å; F297-F308 AromaticContact CE2-CD1 3.98Å; F297-F308 HydrophobicContact CE2-CD1 3.98Å; F297-F308 AromaticContact CE2-CG 3.73Å; F297-F308 HydrophobicContact CE2-CG 3.73Å; F297-F308 HydrophobicContact CZ-CB 3.85Å; F297-F308 HydrophobicContact CZ-CG 4.12Å
298D98.3Very high98.5Very high16 Ų1626.3 Ų26.39%0.08614%0.135CC..  trans-55.9147.4177.8177.268.5000111.9S250 Y253 Y258 D300 D301 W305S250-D298 WeakPolarHBondContact CA-OD1 3.47Å; S250-D298 WeakPolarHBondContact CB-OD1 3.39Å; S250-D298 WeakPolarHBondContact OG-CA 3.47Å; S250-D298 PolarHBondContact OG-OD1 3.46Å; Y253-D298 HydrophobicContact CD1-CB 3.91Å; Y253-D298 HydrophobicContact CD2-CB 3.82Å; Y253-D298 HydrophobicContact CE1-CB 4.32Å; Y253-D298 HydrophobicContact CE2-CB 4.24Å; Y253-D298 HydrophobicContact CG-CB 3.62Å; Y258-D298 HydrophobicContact CE1-CB 4.23Å; Y258-D298 PolarHBondContact OH-N 2.81Å; D298-D300 PolarHBondContact O-N 2.92Å; D298-D300 PolarHBondContact OD2-N 2.99Å; D298-D301 HydrophobicContact CB-CB 4.08Å; D298-D301 PolarHBondContact O-N 3.35Å; D298-W305 PolarHBondContact O-NE1 3.11Å
299Q97.1Very high98.5Very high23 Ų2326.7 Ų26.711%0.10714%0.139CC..THydrogen-bonded Turntrans-53.3-21.8-178.867.4-166.1-41.700114.3I44 S250 D320 L321 R328I44-Q299 VanDerWaalsContact N-OE1 3.13Å; S250-Q299 PolarHBondContact OG-N 2.96Å; Q299-D320 HydrophobicContact CB-CB 4.03Å; Q299-L321 WeakPolarHBondContact O-CD1 3.27Å; Q299-R328 PolarHBondContact O-NH2 3Å
300D97.8Very high98.5Very high64 Ų6428 Ų2834%0.34216%0.155SC..THydrogen-bonded Turntrans-115.23.1176-68.3-44.2000114.8Y45 D298 W302 R328Y45-D300 PolarHBondContact OH-OD1 2.77Å; Y45-D300 PolarHBondContact OH-OD2 3.35Å; D298-D300 PolarHBondContact O-N 2.92Å; D298-D300 PolarHBondContact OD2-N 2.99Å; D300-W302 VanDerWaalsContact O-CD1 3.23Å; D300-W302 PolarHBondContact O-N 3.25Å; D300-R328 IonicContact OD1-CZ 2.64Å; D300-R328 IonicContact OD1-NH1 3.42Å; D300-R328 PolarHBondContact OD1-NH1 2.81Å; D300-R328 IonicContact OD1-NH2 3.79Å; D300-R328 PolarHBondContact OD1-NH2 3.23Å
301D98Very high98.4Very high26 Ų2631.8 Ų31.814%0.13918%0.178CC..  trans-81.753.7175.6-167.9-1.3000112.4Y258 F297 D298 E303 A304 W305Y258-D301 PolarHBondContact OH-OD2 3.38Å; F297-D301 HydrophobicContact CB-CB 4.28Å; D298-D301 HydrophobicContact CB-CB 4.08Å; D298-D301 PolarHBondContact O-N 3.35Å; D301-E303 PolarHBondContact O-N 2.99Å; D301-A304 HydrophobicContact CB-CB 4.32Å; D301-A304 PolarHBondContact O-N 2.9Å; D301-A304 VanDerWaalsContact OD1-CB 3.3Å; D301-A304 WeakPolarHBondContact OD1-CB 3.49Å; D301-A304 PolarHBondContact OD1-N 3.16Å; D301-A304 VanDerWaalsContact OD2-CB 3.26Å; D301-A304 WeakPolarHBondContact OD2-CB 3.32Å; D301-W305 VanDerWaalsContact O-CD1 3.22Å; D301-W305 PolarHBondContact O-N 3.3Å
302W98.6Very high98.3Very high33 Ų3331.4 Ų31.413%0.12518%0.176CC..Hα-helixtrans-53.3-30.8-174.8-68.694.7000114D300 T306 L321 R328 K331 A337D300-W302 VanDerWaalsContact O-CD1 3.23Å; D300-W302 PolarHBondContact O-N 3.25Å; W302-T306 WeakPolarHBondContact O-CB 3.17Å; W302-T306 PolarHBondContact O-N 3.37Å; W302-T306 PolarHBondContact O-OG1 3Å; W302-L321 HydrophobicContact CD2-CD1 3.92Å; W302-L321 HydrophobicContact CE3-CD1 3.76Å; W302-L321 HydrophobicContact CH2-CD1 3.58Å; W302-L321 HydrophobicContact CH2-CG 3.91Å; W302-L321 HydrophobicContact CZ2-CD1 3.77Å; W302-L321 HydrophobicContact CZ2-CG 4.49Å; W302-L321 HydrophobicContact CZ3-CD1 3.55Å; W302-L321 HydrophobicContact CZ3-CD2 4.08Å; W302-L321 HydrophobicContact CZ3-CG 3.93Å; W302-R328 VanDerWaalsContact CZ2-NH2 3.26Å; W302-K331 HydrophobicContact CD2-CD 4.2Å; W302-K331 VanDerWaalsContact CD2-CE 3.43Å; W302-K331 HydrophobicContact CD2-CG 4.45Å; W302-K331 HydrophobicContact CE3-CD 4.46Å; W302-K331 HydrophobicContact CE3-CG 4.21Å; W302-K331 HydrophobicContact CH2-CB 4.06Å; W302-K331 HydrophobicContact CH2-CD 3.97Å; W302-K331 HydrophobicContact CH2-CG 3.81Å; W302-K331 HydrophobicContact CZ2-CB 4.49Å; W302-K331 HydrophobicContact CZ2-CD 3.63Å; W302-K331 HydrophobicContact CZ2-CG 4.02Å; W302-K331 HydrophobicContact CZ3-CB 4.43Å; W302-K331 HydrophobicContact CZ3-CD 4.39Å; W302-K331 HydrophobicContact CZ3-CG 3.93Å; W302-A337 HydrophobicContact CE3-CB 3.76Å; W302-A337 HydrophobicContact CZ3-CB 3.86Å
303E98.5Very high98.2Very high123 Ų12336.2 Ų36.258%0.57521%0.209SC*.Hα-helixtrans-67.2-47.2177.5-171.1-177.1159.400111.2D301 T306 K307D301-E303 PolarHBondContact O-N 2.99Å; E303-T306 PolarHBondContact O-N 3.35Å; E303-K307 HydrophobicContact CG-CD 4.13Å; E303-K307 WeakPolarHBondContact O-CB 3.45Å; E303-K307 WeakPolarHBondContact O-CG 3.39Å; E303-K307 PolarHBondContact O-N 3.45Å; E303-K307 WeakPolarHBondContact OE1-CE 3.42Å; E303-K307 IonicContact OE1-NZ 2.89Å; E303-K307 PolarHBondContact OE1-NZ 3.5Å
304A98.7Very high98.2Very high6 Ų636.8 Ų36.85%0.0521%0.212CC..Hα-helixtrans-63.4-43.8177.600000112.1P274 F297 D301 T306 K307 F308P274-A304 HydrophobicContact CB-CB 3.65Å; P274-A304 HydrophobicContact CG-CB 4.46Å; F297-A304 HydrophobicContact CB-CB 4.08Å; F297-A304 HydrophobicContact CD1-CB 3.59Å; F297-A304 HydrophobicContact CD2-CB 3.9Å; F297-A304 HydrophobicContact CE1-CB 3.99Å; F297-A304 HydrophobicContact CE2-CB 4.3Å; F297-A304 HydrophobicContact CG-CB 3.54Å; F297-A304 HydrophobicContact CZ-CB 4.33Å; D301-A304 HydrophobicContact CB-CB 4.32Å; D301-A304 PolarHBondContact O-N 2.9Å; D301-A304 VanDerWaalsContact OD1-CB 3.3Å; D301-A304 WeakPolarHBondContact OD1-CB 3.49Å; D301-A304 PolarHBondContact OD1-N 3.16Å; D301-A304 VanDerWaalsContact OD2-CB 3.26Å; D301-A304 WeakPolarHBondContact OD2-CB 3.32Å; A304-T306 PolarHBondContact O-N 3.34Å; A304-K307 PolarHBondContact O-N 2.94Å; A304-F308 WeakPolarHBondContact O-CB 3.38Å; A304-F308 PolarHBondContact O-N 3.02Å
305W98.8Very high98.2Very high0 Ų036.7 Ų36.70%021%0.212CC..Hα-helixtrans-53.9-52.7173.5-80.795.2000112.1D295 P296 F297 D298 D301 K307 F308 T309 V316 V317 L321 A337 C338D295-W305 HydrophobicContact CB-CH2 4.4Å; D295-W305 HydrophobicContact CB-CZ2 4.32Å; D295-W305 VanDerWaalsContact OD1-CH2 3.23Å; D295-W305 WeakPolarHBondContact OD1-CH2 3.17Å; D295-W305 WeakPolarHBondContact OD1-CZ2 3.31Å; P296-W305 HydrophobicContact CG-CD2 4.44Å; P296-W305 HydrophobicContact CG-CE3 4.08Å; P296-W305 HydrophobicContact CG-CH2 4.3Å; P296-W305 HydrophobicContact CG-CZ3 4.04Å; F297-W305 HydrophobicContact CB-CG 4.32Å; F297-W305 HydrophobicContact CD2-CD2 4.48Å; F297-W305 HydrophobicContact CD2-CG 4.25Å; F297-W305 PolarHBondContact O-NE1 3.25Å; D298-W305 PolarHBondContact O-NE1 3.11Å; D301-W305 VanDerWaalsContact O-CD1 3.22Å; D301-W305 PolarHBondContact O-N 3.3Å; W305-K307 PolarHBondContact O-N 3.45Å; W305-F308 PolarHBondContact O-N 3.06Å; W305-T309 WeakPolarHBondContact O-CB 3.36Å; W305-T309 PolarHBondContact O-N 2.98Å; W305-T309 PolarHBondContact O-OG1 2.77Å; W305-T309 VanDerWaalsContact O-OG1 3.11Å; W305-V316 HydrophobicContact CE3-CG1 4Å; W305-V316 HydrophobicContact CZ3-CG1 3.82Å; W305-V317 WeakPolarHBondContact CH2-O 3.32Å; W305-V317 WeakPolarHBondContact CZ3-O 3.36Å; W305-L321 HydrophobicContact CD2-CD1 4.32Å; W305-L321 HydrophobicContact CD2-CD2 3.67Å; W305-L321 HydrophobicContact CD2-CG 4.42Å; W305-L321 HydrophobicContact CE3-CD2 3.64Å; W305-L321 HydrophobicContact CG-CD1 4.32Å; W305-L321 HydrophobicContact CG-CD2 4.22Å; W305-L321 HydrophobicContact CH2-CB 3.86Å; W305-L321 HydrophobicContact CH2-CD2 3.93Å; W305-L321 HydrophobicContact CH2-CG 4.47Å; W305-L321 HydrophobicContact CZ2-CB 3.6Å; W305-L321 HydrophobicContact CZ2-CD1 4.47Å; W305-L321 HydrophobicContact CZ2-CD2 4.04Å; W305-L321 HydrophobicContact CZ2-CG 4.23Å; W305-L321 HydrophobicContact CZ3-CD2 3.75Å; W305-A337 CarbonylContact C-O 3.3Å; W305-A337 HydrophobicContact CB-CB 3.97Å; W305-C338 HydrophobicContact CE3-CB 4.03Å; W305-C338 HydrophobicContact CZ3-CB 3.86Å
306T98.8Very high98.2Very high45 Ų4536.6 Ų36.628%0.27621%0.211SC..Hα-helixtrans-62.1-46.4-178.6-58.80000111.7W302 E303 A304 A310 D335W302-T306 WeakPolarHBondContact O-CB 3.17Å; W302-T306 PolarHBondContact O-N 3.37Å; W302-T306 PolarHBondContact O-OG1 3Å; E303-T306 PolarHBondContact O-N 3.35Å; A304-T306 PolarHBondContact O-N 3.34Å; T306-A310 WeakPolarHBondContact O-CB 3.45Å; T306-A310 PolarHBondContact O-N 3.35Å; T306-A310 VanDerWaalsContact O-N 3.1Å; T306-D335 WeakPolarHBondContact CG2-O 3.27Å; T306-D335 PolarHBondContact OG1-O 2.71Å
307K98.5Very high98.2Very high96 Ų9636.6 Ų36.642%0.41721%0.211SC..Hα-helixtrans-60-48.7177.6-79173.9170173.80111.5E303 A304 W305 A310 T311E303-K307 HydrophobicContact CG-CD 4.13Å; E303-K307 WeakPolarHBondContact O-CB 3.45Å; E303-K307 WeakPolarHBondContact O-CG 3.39Å; E303-K307 PolarHBondContact O-N 3.45Å; E303-K307 WeakPolarHBondContact OE1-CE 3.42Å; E303-K307 IonicContact OE1-NZ 2.89Å; E303-K307 PolarHBondContact OE1-NZ 3.5Å; A304-K307 PolarHBondContact O-N 2.94Å; W305-K307 PolarHBondContact O-N 3.45Å; K307-A310 PolarHBondContact O-N 3.26Å; K307-T311 WeakPolarHBondContact O-CG2 3.2Å; K307-T311 PolarHBondContact O-N 3.03Å
308F98.8Very high98.2Very high2 Ų236.6 Ų36.61%0.00921%0.211CC..Hα-helixtrans-65.8-48.1-178.2178-112.5000112A278 Y281 K282 I293 P296 F297 A304 W305 A310 T311 T312 V316A278-F308 HydrophobicContact CB-CD2 4.02Å; Y281-F308 HydrophobicContact CD2-CE2 4.13Å; Y281-F308 HydrophobicContact CD2-CZ 4.13Å; Y281-F308 HydrophobicContact CG-CE2 4.43Å; Y281-F308 HydrophobicContact CG-CZ 4.32Å; K282-F308 HydrophobicContact CG-CE2 4.44Å; I293-F308 HydrophobicContact CD1-CZ 4.17Å; P296-F308 HydrophobicContact CB-CD1 4.37Å; P296-F308 HydrophobicContact CB-CE1 4.34Å; P296-F308 HydrophobicContact CG-CD1 4.16Å; P296-F308 HydrophobicContact CG-CE1 4.34Å; F297-F308 HydrophobicContact CD2-CB 4.48Å; F297-F308 HydrophobicContact CE2-CB 3.37Å; F297-F308 AromaticContact CE2-CD1 3.98Å; F297-F308 HydrophobicContact CE2-CD1 3.98Å; F297-F308 AromaticContact CE2-CG 3.73Å; F297-F308 HydrophobicContact CE2-CG 3.73Å; F297-F308 HydrophobicContact CZ-CB 3.85Å; F297-F308 HydrophobicContact CZ-CG 4.12Å; A304-F308 WeakPolarHBondContact O-CB 3.38Å; A304-F308 PolarHBondContact O-N 3.02Å; W305-F308 PolarHBondContact O-N 3.06Å; F308-A310 PolarHBondContact O-N 3.08Å; F308-T311 PolarHBondContact O-N 3.13Å; F308-T311 PolarHBondContact O-OG1 3.09Å; F308-T312 HydrophobicContact CE1-CG2 4.21Å; F308-T312 HydrophobicContact CZ-CG2 4.31Å; F308-T312 PolarHBondContact O-N 2.73Å; F308-V316 HydrophobicContact CD1-CG2 4.27Å; F308-V316 HydrophobicContact CE1-CG2 4.03Å
309T98.8Very high98.2Very high19 Ų1935.9 Ų35.912%0.11721%0.208CC..Hα-helixtrans-58.8-35179.2-66.90000111.9W305 T311 K336 A337W305-T309 WeakPolarHBondContact O-CB 3.36Å; W305-T309 PolarHBondContact O-N 2.98Å; W305-T309 PolarHBondContact O-OG1 2.77Å; W305-T309 VanDerWaalsContact O-OG1 3.11Å; T309-T311 PolarHBondContact O-N 2.76Å; T309-K336 WeakPolarHBondContact CG2-O 3.48Å; T309-A337 WeakPolarHBondContact CB-O 3.38Å; T309-A337 PolarHBondContact OG1-O 3.47Å
310A98.4Very high98.1Very high87 Ų8735 Ų3572%0.71920%0.203SC*.Hα-helixtrans-67.3-19.6174.800000114.2T306 K307 F308T306-A310 WeakPolarHBondContact O-CB 3.45Å; T306-A310 PolarHBondContact O-N 3.35Å; T306-A310 VanDerWaalsContact O-N 3.1Å; K307-A310 PolarHBondContact O-N 3.26Å; F308-A310 PolarHBondContact O-N 3.08Å
311T97.2Very high98.1Very high84 Ų8431.9 Ų31.952%0.51519%0.187SC..THydrogen-bonded Turntrans-101.1-1.1-175.565.10000114.4K282 K307 F308 T309K282-T311 WeakPolarHBondContact CE-OG1 3.5Å; K307-T311 WeakPolarHBondContact O-CG2 3.2Å; K307-T311 PolarHBondContact O-N 3.03Å; F308-T311 PolarHBondContact O-N 3.13Å; F308-T311 PolarHBondContact O-OG1 3.09Å; T309-T311 PolarHBondContact O-N 2.76Å
312T96.7Very high98.1Very high29 Ų2930.7 Ų30.718%0.17818%0.18CC..  trans-134.1149.8-175.6-167.70000112.9F308 I314 V316F308-T312 HydrophobicContact CE1-CG2 4.21Å; F308-T312 HydrophobicContact CZ-CG2 4.31Å; F308-T312 PolarHBondContact O-N 2.73Å; T312-I314 HydrophobicContact CG2-CG1 3.93Å; T312-I314 WeakPolarHBondContact OG1-CG1 3.32Å; T312-I314 PolarHBondContact OG1-N 2.78Å; T312-V316 HydrophobicContact CG2-CG2 3.84Å
313S96.3Very high98Very high103 Ų10329.1 Ų29.172%0.7218%0.175SC*.  trans-97.5-6.1175.2610000113.2R430S313-R430 PolarHBondContact O-NH1 2.94Å
314I98.6Very high98Very high12 Ų1223.3 Ų23.36%0.06215%0.147CC..SBendtrans-70.5174.3-178.876.3170000111.2V285 V291 I293 T312 V316 N339 R430V285-I314 HydrophobicContact CG1-CG2 3.77Å; V285-I314 HydrophobicContact CG2-CD1 3.71Å; V285-I314 HydrophobicContact CG2-CG2 4.32Å; V291-I314 WeakPolarHBondContact O-CB 3.38Å; I293-I314 HydrophobicContact CB-CD1 4.23Å; I293-I314 HydrophobicContact CD1-CD1 3.67Å; I293-I314 HydrophobicContact CG1-CD1 3.68Å; T312-I314 HydrophobicContact CG2-CG1 3.93Å; T312-I314 WeakPolarHBondContact OG1-CG1 3.32Å; T312-I314 PolarHBondContact OG1-N 2.78Å; I314-V316 HydrophobicContact CG1-CG2 4.47Å; I314-N339 PolarHBondContact O-ND2 2.86Å; I314-R430 PolarHBondContact O-NH2 2.9Å; I314-R430 VanDerWaalsContact O-NH2 3.08Å
315Q98.9Very high97.8Very high0 Ų024.7 Ų24.70%015%0.154CC..EExtended strand (participates in β ladder)trans-73.1129.1168.1-175.9168.9-89.300110.4V291 S292 I293 V317 N339 C340V291-Q315 WeakPolarHBondContact O-CB 3.1Å; V291-Q315 PolarHBondContact O-N 3.07Å; S292-Q315 CarbonylContact C-O 3.59Å; S292-Q315 VanDerWaalsContact CA-O 3.28Å; S292-Q315 WeakPolarHBondContact CA-O 3.37Å; S292-Q315 PolarHBondContact OG-NE2 3.1Å; I293-Q315 PolarHBondContact N-O 2.99Å; Q315-V317 HydrophobicContact CG-CG2 3.83Å; Q315-N339 VanDerWaalsContact CA-OD1 3.32Å; Q315-N339 WeakPolarHBondContact CA-OD1 3.5Å; Q315-C340 VanDerWaalsContact CD-SG 3.56Å; Q315-C340 HydrophobicContact CG-CB 3.48Å; Q315-C340 VanDerWaalsContact CG-CB 3.48Å
316V98.9Very high97.7Very high0 Ų026.9 Ų26.90%017%0.168CC..EExtended strand (participates in β ladder)trans-116.4115171.3-1770000106.9I293 P296 W305 F308 T312 I314 C338 N339 C340I293-V316 CarbonylContact O-C 3.44Å; I293-V316 WeakPolarHBondContact O-CA 3.25Å; P296-V316 HydrophobicContact CG-CG1 4.12Å; W305-V316 HydrophobicContact CE3-CG1 4Å; W305-V316 HydrophobicContact CZ3-CG1 3.82Å; F308-V316 HydrophobicContact CD1-CG2 4.27Å; F308-V316 HydrophobicContact CE1-CG2 4.03Å; T312-V316 HydrophobicContact CG2-CG2 3.84Å; I314-V316 HydrophobicContact CG1-CG2 4.47Å; V316-C338 HydrophobicContact CB-CB 4.36Å; V316-C338 HydrophobicContact CG1-CB 4Å; V316-C338 WeakPolarHBondContact O-CB 3.14Å; V316-N339 PolarHBondContact N-OD1 3.23Å; V316-N339 PolarHBondContact O-N 3.02Å; V316-N339 PolarHBondContact O-OD1 3.18Å; V316-C340 PolarHBondContact O-N 3.28Å
317V98.9Very high97.5Very high0 Ų031.4 Ų31.40%018%0.184CC..EExtended strand (participates in β ladder)trans-101.4126.6-172-168.90000109.3S292 I293 E294 D295 W305 Q315 C340 L342S292-V317 WeakPolarHBondContact OG-CG2 3.41Å; I293-V317 PolarHBondContact O-N 3.26Å; E294-V317 WeakPolarHBondContact CA-O 3.44Å; E294-V317 HydrophobicContact CB-CB 3.8Å; E294-V317 HydrophobicContact CB-CG1 4.42Å; E294-V317 HydrophobicContact CB-CG2 4.34Å; E294-V317 HydrophobicContact CG-CB 4.06Å; E294-V317 HydrophobicContact CG-CG1 4.2Å; D295-V317 PolarHBondContact N-O 3.49Å; D295-V317 VanDerWaalsContact N-O 3.12Å; W305-V317 WeakPolarHBondContact CH2-O 3.32Å; W305-V317 WeakPolarHBondContact CZ3-O 3.36Å; Q315-V317 HydrophobicContact CG-CG2 3.83Å; V317-C340 CarbonylContact C-O 3.57Å; V317-C340 WeakPolarHBondContact CA-O 3.48Å; V317-C340 HydrophobicContact CB-CB 4.34Å; V317-C340 HydrophobicContact CG1-CB 4.39Å; V317-C340 HydrophobicContact CG2-CB 3.97Å; V317-L342 HydrophobicContact CG1-CB 3.74Å; V317-L342 HydrophobicContact CG1-CD1 4.18Å
318G98.6Very high97.5Very high0 Ų028.2 Ų28.20%017%0.169CC..EExtended strand (participates in β ladder)trans-92.8115.5168.800000111T322 C340 L342G318-T322 PolarHBondContact O-OG1 2.73Å; G318-C340 PolarHBondContact N-O 2.7Å; G318-L342 PolarHBondContact O-N 2.98Å
319D97.6Very high97.5Very high2 Ų228.1 Ų28.11%0.01117%0.169CC..SBendtrans-104.9-84.2170.7175.926.7000109.8E294 D295 L321 T322 V323 L342 K344 Q347E294-D319 HydrophobicContact CG-CB 3.98Å; D295-D319 PolarHBondContact OD1-N 3.33Å; D295-D319 WeakPolarHBondContact OD2-CB 3.3Å; D319-L321 PolarHBondContact O-N 3.14Å; D319-T322 PolarHBondContact O-N 2.99Å; D319-T322 PolarHBondContact O-OG1 3.06Å; D319-V323 WeakPolarHBondContact O-CA 3.27Å; D319-V323 PolarHBondContact O-N 3.45Å; D319-L342 HydrophobicContact CB-CB 3.82Å; D319-L342 HydrophobicContact CB-CD2 3.61Å; D319-L342 HydrophobicContact CB-CG 4.36Å; D319-L342 WeakPolarHBondContact OD2-CD2 3.16Å; D319-K344 WeakPolarHBondContact OD1-CE 3.21Å; D319-K344 IonicContact OD1-NZ 3.99Å; D319-K344 PolarHBondContact OD1-NZ 3.01Å; D319-K344 IonicContact OD2-NZ 2.7Å; D319-K344 PolarHBondContact OD2-NZ 3.28Å; D319-Q347 PolarHBondContact OD1-NE2 3.38Å
320D95Very high97.5Very high3 Ų329.5 Ų29.52%0.01618%0.182CC..THydrogen-bonded Turntrans-63.8-27.4177.4-72.1-27.7000112G43 D295 Q299 T322 V323G43-D320 WeakPolarHBondContact CA-OD1 3.46Å; G43-D320 PolarHBondContact N-OD1 2.97Å; G43-D320 VanDerWaalsContact N-OD1 3.16Å; D295-D320 PolarHBondContact OD1-N 3.45Å; D295-D320 VanDerWaalsContact OD2-CB 3.31Å; D295-D320 WeakPolarHBondContact OD2-CB 3.36Å; D295-D320 PolarHBondContact OD2-N 2.94Å; Q299-D320 HydrophobicContact CB-CB 4.03Å; D320-T322 PolarHBondContact O-N 3.05Å; D320-V323 WeakPolarHBondContact O-CG1 3.47Å
321L98Very high97.5Very high0 Ų029.5 Ų29.50%017%0.166CC..THydrogen-bonded Turntrans-57-38.7171-179.770.2000112.1Q299 W302 W305 D319 R328 A337 C338Q299-L321 WeakPolarHBondContact O-CD1 3.27Å; W302-L321 HydrophobicContact CD2-CD1 3.92Å; W302-L321 HydrophobicContact CE3-CD1 3.76Å; W302-L321 HydrophobicContact CH2-CD1 3.58Å; W302-L321 HydrophobicContact CH2-CG 3.91Å; W302-L321 HydrophobicContact CZ2-CD1 3.77Å; W302-L321 HydrophobicContact CZ2-CG 4.49Å; W302-L321 HydrophobicContact CZ3-CD1 3.55Å; W302-L321 HydrophobicContact CZ3-CD2 4.08Å; W302-L321 HydrophobicContact CZ3-CG 3.93Å; W305-L321 HydrophobicContact CD2-CD1 4.32Å; W305-L321 HydrophobicContact CD2-CD2 3.67Å; W305-L321 HydrophobicContact CD2-CG 4.42Å; W305-L321 HydrophobicContact CE3-CD2 3.64Å; W305-L321 HydrophobicContact CG-CD1 4.32Å; W305-L321 HydrophobicContact CG-CD2 4.22Å; W305-L321 HydrophobicContact CH2-CB 3.86Å; W305-L321 HydrophobicContact CH2-CD2 3.93Å; W305-L321 HydrophobicContact CH2-CG 4.47Å; W305-L321 HydrophobicContact CZ2-CB 3.6Å; W305-L321 HydrophobicContact CZ2-CD1 4.47Å; W305-L321 HydrophobicContact CZ2-CD2 4.04Å; W305-L321 HydrophobicContact CZ2-CG 4.23Å; W305-L321 HydrophobicContact CZ3-CD2 3.75Å; D319-L321 PolarHBondContact O-N 3.14Å; L321-R328 PolarHBondContact O-NE 3.26Å; L321-A337 HydrophobicContact CD2-CB 4.1Å; L321-C338 HydrophobicContact CD2-CB 4.38Å
322T98.2Very high97.6Very high0 Ų025.5 Ų25.50%014%0.142CC..THydrogen-bonded Turntrans-112.5-26.8-17069.30000113.6G318 D319 D320 T324 N325 I329 L341 W366G318-T322 PolarHBondContact O-OG1 2.73Å; D319-T322 PolarHBondContact O-N 2.99Å; D319-T322 PolarHBondContact O-OG1 3.06Å; D320-T322 PolarHBondContact O-N 3.05Å; T322-T324 PolarHBondContact O-N 3.22Å; T322-N325 WeakPolarHBondContact O-CB 3.46Å; T322-N325 PolarHBondContact O-N 2.96Å; T322-I329 HydrophobicContact CG2-CG1 4.38Å; T322-L341 WeakPolarHBondContact OG1-CD1 3.44Å; T322-W366 HydrophobicContact CG2-CZ3 4.38Å
323V96.4Very high97.6Very high1 Ų125.6 Ų25.61%0.00614%0.142CC..THydrogen-bonded Turntrans41.636.6-177.3-68.10000113.6E46 D319 D320 N325 Q347E46-V323 HydrophobicContact CG-CB 3.91Å; E46-V323 HydrophobicContact CG-CG1 3.68Å; D319-V323 WeakPolarHBondContact O-CA 3.27Å; D319-V323 PolarHBondContact O-N 3.45Å; D320-V323 WeakPolarHBondContact O-CG1 3.47Å; V323-N325 HydrophobicContact CG2-CB 3.76Å; V323-N325 PolarHBondContact O-N 3.41Å; V323-Q347 VanDerWaalsContact C-OE1 3.24Å; V323-Q347 WeakPolarHBondContact O-CB 3.49Å
324T97.9Very high97.7Very high0 Ų024.1 Ų24.10%014%0.137CC..THydrogen-bonded Turntrans51.723-173-45.20000113.4T322 L342 L343 K344 Q347 I348 A357T322-T324 PolarHBondContact O-N 3.22Å; T324-L342 PolarHBondContact OG1-O 2.61Å; T324-L343 HydrophobicContact CG2-CG 4.11Å; T324-K344 PolarHBondContact OG1-N 3.31Å; T324-K344 PolarHBondContact OG1-O 2.79Å; T324-Q347 PolarHBondContact OG1-OE1 3.48Å; T324-I348 HydrophobicContact CG2-CB 4.06Å; T324-I348 HydrophobicContact CG2-CG2 3.91Å; T324-A357 HydrophobicContact CG2-CB 3.99Å
325N95.6Very high97.7Very high35 Ų3526.3 Ų26.319%0.18715%0.148CC..  trans-96.1120.6-175.6-177.2-50.2000110.9T322 V323 K327 R328 I329T322-N325 WeakPolarHBondContact O-CB 3.46Å; T322-N325 PolarHBondContact O-N 2.96Å; V323-N325 HydrophobicContact CG2-CB 3.76Å; V323-N325 PolarHBondContact O-N 3.41Å; N325-K327 PolarHBondContact O-N 2.96Å; N325-K327 VanDerWaalsContact O-N 3.1Å; N325-K327 WeakPolarHBondContact OD1-CB 3.35Å; N325-K327 PolarHBondContact OD1-N 2.87Å; N325-R328 HydrophobicContact CB-CB 4.46Å; N325-R328 HydrophobicContact CB-CG 4.49Å; N325-R328 PolarHBondContact O-N 2.92Å; N325-I329 VanDerWaalsContact O-CG1 3.31Å; N325-I329 WeakPolarHBondContact O-CG1 3.44Å; N325-I329 PolarHBondContact O-N 2.8Å
326P95Very high97.7Very high47 Ų4733.7 Ų33.731%0.30518%0.18SC..Hα-helixtrans-53.9-34.2-177.7-29.536.1000115.2A330 L360P326-A330 VanDerWaalsContact O-CB 3.3Å; P326-A330 WeakPolarHBondContact O-CB 3.19Å; P326-A330 PolarHBondContact O-N 3.43Å; P326-L360 HydrophobicContact CB-CD2 4.29Å
327K96.1Very high97.7Very high140 Ų14033.7 Ų33.761%0.60918%0.18SC*.Hα-helixtrans-68.2-43.4178.7-64-179.8-179.21760111.5E102 N325 A330 K331E102-K327 IonicContact OE1-NZ 2.97Å; E102-K327 PolarHBondContact OE1-NZ 3.04Å; N325-K327 PolarHBondContact O-N 2.96Å; N325-K327 VanDerWaalsContact O-N 3.1Å; N325-K327 WeakPolarHBondContact OD1-CB 3.35Å; N325-K327 PolarHBondContact OD1-N 2.87Å; K327-A330 PolarHBondContact O-N 2.84Å; K327-K331 PolarHBondContact O-N 2.92Å
328R97.9Very high97.7Very high28 Ų2833.9 Ų33.911%0.10618%0.181CC..Hα-helixtrans-73.3-37.2178.4-64.2-163.873.497.4-7111.7Y45 Q299 D300 W302 L321 N325 A330 K331 G332Y45-R328 VanDerWaalsContact CD2-CZ 3.5Å; Y45-R328 VanDerWaalsContact CE2-CZ 3.47Å; Q299-R328 PolarHBondContact O-NH2 3Å; D300-R328 IonicContact OD1-CZ 2.64Å; D300-R328 IonicContact OD1-NH1 3.42Å; D300-R328 PolarHBondContact OD1-NH1 2.81Å; D300-R328 IonicContact OD1-NH2 3.79Å; D300-R328 PolarHBondContact OD1-NH2 3.23Å; W302-R328 VanDerWaalsContact CZ2-NH2 3.26Å; L321-R328 PolarHBondContact O-NE 3.26Å; N325-R328 HydrophobicContact CB-CB 4.46Å; N325-R328 HydrophobicContact CB-CG 4.49Å; N325-R328 PolarHBondContact O-N 2.92Å; R328-A330 PolarHBondContact O-N 2.83Å; R328-K331 PolarHBondContact O-N 2.96Å; R328-G332 PolarHBondContact O-N 3.43Å
329I98.6Very high97.7Very high0 Ų035.4 Ų35.40%019%0.19CC..Hα-helixtrans-57.8-49.4171-64.5165.2000110.1T322 N325 K331 G332 V333 L341 A357 L360 W366T322-I329 HydrophobicContact CG2-CG1 4.38Å; N325-I329 VanDerWaalsContact O-CG1 3.31Å; N325-I329 WeakPolarHBondContact O-CG1 3.44Å; N325-I329 PolarHBondContact O-N 2.8Å; I329-K331 VanDerWaalsContact C-N 3.31Å; I329-K331 PolarHBondContact O-N 3.44Å; I329-G332 PolarHBondContact O-N 3.31Å; I329-G332 VanDerWaalsContact O-N 3.16Å; I329-V333 HydrophobicContact CG2-CG2 4.47Å; I329-V333 WeakPolarHBondContact O-CG2 3.36Å; I329-V333 PolarHBondContact O-N 2.84Å; I329-L341 HydrophobicContact CD1-CD1 3.94Å; I329-L341 HydrophobicContact CD1-CD2 3.87Å; I329-L341 HydrophobicContact CG1-CD1 4.07Å; I329-A357 HydrophobicContact CD1-CB 3.79Å; I329-L360 HydrophobicContact CB-CD2 3.94Å; I329-L360 HydrophobicContact CG2-CD2 3.63Å; I329-L360 HydrophobicContact CG2-CG 3.83Å; I329-W366 HydrophobicContact CG2-CZ3 4.25Å
330A98.3Very high97.8Very high48 Ų4835.3 Ų35.340%0.39719%0.189SC..Hα-helixtrans-59.8-40.1178.300000112.5P326 K327 R328 V333 A334P326-A330 VanDerWaalsContact O-CB 3.3Å; P326-A330 WeakPolarHBondContact O-CB 3.19Å; P326-A330 PolarHBondContact O-N 3.43Å; K327-A330 PolarHBondContact O-N 2.84Å; R328-A330 PolarHBondContact O-N 2.83Å; A330-V333 PolarHBondContact O-N 2.81Å; A330-A334 WeakPolarHBondContact O-CB 3.41Å; A330-A334 PolarHBondContact O-N 3.08Å
331K98.5Very high98Very high87 Ų8735.1 Ų35.138%0.37819%0.188SC..Hα-helixtrans-63-47.5173.1178.9169.3169.451.20111.9W302 K327 R328 I329 V333 A334 D335W302-K331 HydrophobicContact CD2-CD 4.2Å; W302-K331 VanDerWaalsContact CD2-CE 3.43Å; W302-K331 HydrophobicContact CD2-CG 4.45Å; W302-K331 HydrophobicContact CE3-CD 4.46Å; W302-K331 HydrophobicContact CE3-CG 4.21Å; W302-K331 HydrophobicContact CH2-CB 4.06Å; W302-K331 HydrophobicContact CH2-CD 3.97Å; W302-K331 HydrophobicContact CH2-CG 3.81Å; W302-K331 HydrophobicContact CZ2-CB 4.49Å; W302-K331 HydrophobicContact CZ2-CD 3.63Å; W302-K331 HydrophobicContact CZ2-CG 4.02Å; W302-K331 HydrophobicContact CZ3-CB 4.43Å; W302-K331 HydrophobicContact CZ3-CD 4.39Å; W302-K331 HydrophobicContact CZ3-CG 3.93Å; K327-K331 PolarHBondContact O-N 2.92Å; R328-K331 PolarHBondContact O-N 2.96Å; I329-K331 VanDerWaalsContact C-N 3.31Å; I329-K331 PolarHBondContact O-N 3.44Å; K331-V333 VanDerWaalsContact C-N 3.28Å; K331-V333 PolarHBondContact O-N 3.48Å; K331-A334 PolarHBondContact O-N 2.83Å; K331-A334 VanDerWaalsContact O-N 3.12Å; K331-D335 WeakPolarHBondContact CG-OD2 3.35Å; K331-D335 IonicContact NZ-OD2 3.89Å; K331-D335 PolarHBondContact NZ-OD2 2.7Å; K331-D335 WeakPolarHBondContact O-CB 3.45Å; K331-D335 PolarHBondContact O-N 2.94Å
332G98.6Very high98Very high0 Ų035.1 Ų35.10%019%0.188CC..Hα-helixtrans-62.8-34.8178.800000113.3R328 I329 K336 A337 W366R328-G332 PolarHBondContact O-N 3.43Å; I329-G332 PolarHBondContact O-N 3.31Å; I329-G332 VanDerWaalsContact O-N 3.16Å; G332-K336 CarbonylContact O-C 3.57Å; G332-K336 WeakPolarHBondContact O-CA 3.5Å; G332-K336 PolarHBondContact O-N 2.68Å; G332-A337 PolarHBondContact O-N 2.7Å; G332-W366 WeakPolarHBondContact O-CZ2 3.35Å
333V98.5Very high98Very high31 Ų3135.1 Ų35.119%0.18819%0.188CC..Hα-helixtrans-63.2-49.7170.9167.30000110.9I329 A330 K331 D335 K336 N364 W366I329-V333 HydrophobicContact CG2-CG2 4.47Å; I329-V333 WeakPolarHBondContact O-CG2 3.36Å; I329-V333 PolarHBondContact O-N 2.84Å; A330-V333 PolarHBondContact O-N 2.81Å; K331-V333 VanDerWaalsContact C-N 3.28Å; K331-V333 PolarHBondContact O-N 3.48Å; V333-D335 PolarHBondContact O-N 3.16Å; V333-K336 PolarHBondContact O-N 2.89Å; V333-N364 HydrophobicContact CG1-CB 3.85Å; V333-N364 WeakPolarHBondContact CG1-OD1 3.24Å; V333-N364 HydrophobicContact CG2-CB 3.81Å; V333-W366 HydrophobicContact CB-CZ2 4.26Å; V333-W366 HydrophobicContact CG2-CD2 4.2Å; V333-W366 HydrophobicContact CG2-CH2 4.01Å; V333-W366 HydrophobicContact CG2-CZ2 3.63Å; V333-W366 HydrophobicContact CG2-CZ3 4.45Å
334A98.5Very high98.1Very high73 Ų7335.7 Ų35.760%0.60319%0.191SC*.Hα-helixtrans-61.7-43.4-178.200000112.2A330 K331 K336A330-A334 WeakPolarHBondContact O-CB 3.41Å; A330-A334 PolarHBondContact O-N 3.08Å; K331-A334 PolarHBondContact O-N 2.83Å; K331-A334 VanDerWaalsContact O-N 3.12Å; A334-K336 VanDerWaalsContact C-N 3.29Å; A334-K336 PolarHBondContact O-N 3.33Å
335D98.4Very high98.1Very high58 Ų5836 Ų3631%0.3119%0.193SC..Hα-helixtrans-81.1-11-179.1-64.3-11.6000112.4T306 K331 V333 A337T306-D335 WeakPolarHBondContact CG2-O 3.27Å; T306-D335 PolarHBondContact OG1-O 2.71Å; K331-D335 WeakPolarHBondContact CG-OD2 3.35Å; K331-D335 IonicContact NZ-OD2 3.89Å; K331-D335 PolarHBondContact NZ-OD2 2.7Å; K331-D335 WeakPolarHBondContact O-CB 3.45Å; K331-D335 PolarHBondContact O-N 2.94Å; V333-D335 PolarHBondContact O-N 3.16Å; D335-A337 HydrophobicContact CB-CB 4.4Å; D335-A337 PolarHBondContact O-N 3.2Å
336K98.6Very high98.2Very high155 Ų15535.1 Ų35.167%0.67419%0.188SC*.THydrogen-bonded Turntrans55.438.9-170-53.9178.2-178.5177.70112.1T309 G332 V333 A334T309-K336 WeakPolarHBondContact CG2-O 3.48Å; G332-K336 CarbonylContact O-C 3.57Å; G332-K336 WeakPolarHBondContact O-CA 3.5Å; G332-K336 PolarHBondContact O-N 2.68Å; V333-K336 PolarHBondContact O-N 2.89Å; A334-K336 VanDerWaalsContact C-N 3.29Å; A334-K336 PolarHBondContact O-N 3.33Å
337A98.7Very high98.2Very high0 Ų033 Ų330%017%0.174CC..  trans-69.2-35.2-174.500000112.6W302 W305 T309 L321 G332 D335W302-A337 HydrophobicContact CE3-CB 3.76Å; W302-A337 HydrophobicContact CZ3-CB 3.86Å; W305-A337 CarbonylContact C-O 3.3Å; W305-A337 HydrophobicContact CB-CB 3.97Å; T309-A337 WeakPolarHBondContact CB-O 3.38Å; T309-A337 PolarHBondContact OG1-O 3.47Å; L321-A337 HydrophobicContact CD2-CB 4.1Å; G332-A337 PolarHBondContact O-N 2.7Å; D335-A337 HydrophobicContact CB-CB 4.4Å; D335-A337 PolarHBondContact O-N 3.2Å
338C98.8Very high98.3Very high3 Ų326.8 Ų26.82%0.0215%0.147CC..  trans-146.1-179175.568.90000110.6W305 V316 L321 W366W305-C338 HydrophobicContact CE3-CB 4.03Å; W305-C338 HydrophobicContact CZ3-CB 3.86Å; V316-C338 HydrophobicContact CB-CB 4.36Å; V316-C338 HydrophobicContact CG1-CB 4Å; V316-C338 WeakPolarHBondContact O-CB 3.14Å; L321-C338 HydrophobicContact CD2-CB 4.38Å; C338-W366 WeakPolarHBondContact O-CZ2 3.4Å; C338-W366 PolarHBondContact O-NE1 3.11Å; C338-W366 WeakPolarHBondContact SG-CH2 3.37Å; C338-W366 WeakPolarHBondContact SG-CZ3 3.38Å
339N98.8Very high98.2Very high32 Ų3225.4 Ų25.417%0.17114%0.142CC..SBendtrans-136.813.9-178.966.439.3000113.7I314 Q315 V316 W366 G367 R430I314-N339 PolarHBondContact O-ND2 2.86Å; Q315-N339 VanDerWaalsContact CA-OD1 3.32Å; Q315-N339 WeakPolarHBondContact CA-OD1 3.5Å; V316-N339 PolarHBondContact N-OD1 3.23Å; V316-N339 PolarHBondContact O-N 3.02Å; V316-N339 PolarHBondContact O-OD1 3.18Å; N339-W366 VanDerWaalsContact O-CA 3.29Å; N339-W366 WeakPolarHBondContact O-CA 3.42Å; N339-G367 PolarHBondContact O-N 2.84Å; N339-R430 PolarHBondContact ND2-NH2 2.75Å; N339-R430 PolarHBondContact OD1-NH2 3.05Å
340C98.9Very high98.2Very high0 Ų025.4 Ų25.40%014%0.142CC..EExtended strand (participates in β ladder)trans-150.9141.3173.4-176.90000110Q315 V316 V317 G318 G367Q315-C340 VanDerWaalsContact CD-SG 3.56Å; Q315-C340 HydrophobicContact CG-CB 3.48Å; Q315-C340 VanDerWaalsContact CG-CB 3.48Å; V316-C340 PolarHBondContact O-N 3.28Å; V317-C340 CarbonylContact C-O 3.57Å; V317-C340 WeakPolarHBondContact CA-O 3.48Å; V317-C340 HydrophobicContact CB-CB 4.34Å; V317-C340 HydrophobicContact CG1-CB 4.39Å; V317-C340 HydrophobicContact CG2-CB 3.97Å; G318-C340 PolarHBondContact N-O 2.7Å; C340-G367 CarbonylContact C-O 3.56Å; C340-G367 VanDerWaalsContact CA-O 3.25Å; C340-G367 WeakPolarHBondContact CA-O 3.5Å; C340-G367 VanDerWaalsContact SG-C 3.5Å; C340-G367 PolarHBondContact SG-O 3.08Å
341L98.9Very high98.3Very high0 Ų023.2 Ų23.20%012%0.123CC..EExtended strand (participates in β ladder)trans-93.8132.5171.4168.563.9000109.4T322 I329 L343 A357 A361 W366 G367 V368 M369T322-L341 WeakPolarHBondContact OG1-CD1 3.44Å; I329-L341 HydrophobicContact CD1-CD1 3.94Å; I329-L341 HydrophobicContact CD1-CD2 3.87Å; I329-L341 HydrophobicContact CG1-CD1 4.07Å; L341-L343 HydrophobicContact CD2-CB 4.39Å; L341-L343 HydrophobicContact CD2-CD1 4.36Å; L341-L343 HydrophobicContact CG-CB 4.39Å; L341-A357 HydrophobicContact CD2-CB 4.31Å; L341-A361 HydrophobicContact CB-CB 3.92Å; L341-A361 HydrophobicContact CD2-CB 4Å; L341-W366 HydrophobicContact CB-CE3 4.42Å; L341-G367 PolarHBondContact N-O 3.49Å; L341-V368 HydrophobicContact CB-CG2 4.34Å; L341-V368 HydrophobicContact CD2-CG1 4.41Å; L341-V368 CarbonylContact O-C 3.54Å; L341-V368 WeakPolarHBondContact O-CA 3.42Å; L341-M369 PolarHBondContact O-N 2.83Å
342L98.8Very high98.3Very high0 Ų019.8 Ų19.80%011%0.11CC..EExtended strand (participates in β ladder)trans-84117.7157.9-160.375.2000108.5E294 V317 G318 D319 T324 K344 M369 K395E294-L342 WeakPolarHBondContact OE1-CD2 3.44Å; E294-L342 WeakPolarHBondContact OE2-CD1 3.35Å; V317-L342 HydrophobicContact CG1-CB 3.74Å; V317-L342 HydrophobicContact CG1-CD1 4.18Å; G318-L342 PolarHBondContact O-N 2.98Å; D319-L342 HydrophobicContact CB-CB 3.82Å; D319-L342 HydrophobicContact CB-CD2 3.61Å; D319-L342 HydrophobicContact CB-CG 4.36Å; D319-L342 WeakPolarHBondContact OD2-CD2 3.16Å; T324-L342 PolarHBondContact OG1-O 2.61Å; L342-K344 HydrophobicContact CD2-CD 4.2Å; L342-K344 HydrophobicContact CD2-CG 4.44Å; L342-M369 WeakPolarHBondContact CA-O 3.33Å; L342-M369 HydrophobicContact CD1-CB 3.9Å; L342-M369 HydrophobicContact CD1-CG 3.87Å; L342-M369 HydrophobicContact CD1-SD 3.8Å; L342-K395 HydrophobicContact CD1-CD 4.36Å
343L98.8Very high98.3Very high0 Ų021.4 Ų21.40%012%0.117CC..EExtended strand (participates in β ladder)trans-100.2108-176.3-172.6150.3000110T324 L341 V345 S354 C358 V368 M369 V370 S371 L385 L389T324-L343 HydrophobicContact CG2-CG 4.11Å; L341-L343 HydrophobicContact CD2-CB 4.39Å; L341-L343 HydrophobicContact CD2-CD1 4.36Å; L341-L343 HydrophobicContact CG-CB 4.39Å; L343-V345 HydrophobicContact CD2-CG1 3.93Å; L343-S354 WeakPolarHBondContact CD1-O 3.36Å; L343-C358 HydrophobicContact CD1-CB 3.62Å; L343-V368 HydrophobicContact CB-CG1 3.72Å; L343-V368 HydrophobicContact CD1-CG1 3.91Å; L343-V368 HydrophobicContact CG-CG1 4.48Å; L343-M369 PolarHBondContact N-O 2.94Å; L343-V370 HydrophobicContact CD2-CG2 4.49Å; L343-S371 PolarHBondContact O-N 3.04Å; L343-L385 HydrophobicContact CD2-CD2 3.94Å; L343-L389 HydrophobicContact CD1-CD1 4.23Å
344K98.5Very high98.3Very high13 Ų1319.9 Ų19.96%0.05711%0.108CC..  trans-114.5107.3173.8-71.3167169.8165.90108.8D319 T324 L342 N346 Q347D319-K344 WeakPolarHBondContact OD1-CE 3.21Å; D319-K344 IonicContact OD1-NZ 3.99Å; D319-K344 PolarHBondContact OD1-NZ 3.01Å; D319-K344 IonicContact OD2-NZ 2.7Å; D319-K344 PolarHBondContact OD2-NZ 3.28Å; T324-K344 PolarHBondContact OG1-N 3.31Å; T324-K344 PolarHBondContact OG1-O 2.79Å; L342-K344 HydrophobicContact CD2-CD 4.2Å; L342-K344 HydrophobicContact CD2-CG 4.44Å; K344-N346 PolarHBondContact O-N 2.91Å; K344-Q347 HydrophobicContact CB-CB 4.21Å; K344-Q347 HydrophobicContact CB-CG 3.59Å; K344-Q347 VanDerWaalsContact CD-CD 3.47Å; K344-Q347 HydrophobicContact CD-CG 3.99Å; K344-Q347 HydrophobicContact CG-CG 4.44Å; K344-Q347 WeakPolarHBondContact O-CB 3.37Å; K344-Q347 PolarHBondContact O-N 3.11Å
345V97.8Very high98.3Very high7 Ų717.3 Ų17.34%0.0428%0.084CC..Hα-helixtrans-56.2-30.8-174-66.20000114L113 L343 G349 L385L113-V345 HydrophobicContact CD1-CB 4.23Å; L113-V345 HydrophobicContact CD1-CG2 4.43Å; L113-V345 HydrophobicContact CD2-CG2 4.15Å; L343-V345 HydrophobicContact CD2-CG1 3.93Å; V345-G349 PolarHBondContact O-N 3.46Å; V345-L385 HydrophobicContact CG1-CD2 3.37Å
346N96.3Very high98.3Very high15 Ų1519.1 Ų19.18%0.089%0.091CC..Hα-helixtrans-80.5-17.8179.976-36.6000113.7V36 P37 L113 K344 I348 R373V36-N346 HydrophobicContact CG1-CB 4.5Å; P37-N346 HydrophobicContact CG-CB 4.35Å; P37-N346 PolarHBondContact O-ND2 2.64Å; L113-N346 VanDerWaalsContact CD2-CA 3.46Å; L113-N346 HydrophobicContact CD2-CB 3.43Å; L113-N346 VanDerWaalsContact CD2-CB 3.43Å; K344-N346 PolarHBondContact O-N 2.91Å; N346-I348 VanDerWaalsContact C-N 3.29Å; N346-R373 VanDerWaalsContact CG-NH1 3.26Å; N346-R373 PolarHBondContact ND2-NH1 3.37Å; N346-R373 VanDerWaalsContact OD1-CD 3.31Å; N346-R373 WeakPolarHBondContact OD1-CD 3.46Å; N346-R373 WeakPolarHBondContact OD1-CG 3.02Å; N346-R373 PolarHBondContact OD1-NH1 3.45Å
347Q95.9Very high98.3Very high2 Ų211.8 Ų11.81%0.0096%0.059CC..Hα-helixtrans-70.3-28.1173-68.2-172.9-41.200111.9E46 A47 D319 V323 T324 K344E46-Q347 VanDerWaalsContact CD-CG 3.45Å; E46-Q347 HydrophobicContact CG-CB 4.08Å; E46-Q347 HydrophobicContact CG-CG 3.77Å; E46-Q347 PolarHBondContact OE1-NE2 3.21Å; A47-Q347 WeakPolarHBondContact CB-O 3.25Å; A47-Q347 PolarHBondContact N-O 2.95Å; D319-Q347 PolarHBondContact OD1-NE2 3.38Å; V323-Q347 VanDerWaalsContact C-OE1 3.24Å; V323-Q347 WeakPolarHBondContact O-CB 3.49Å; T324-Q347 PolarHBondContact OG1-OE1 3.48Å; K344-Q347 HydrophobicContact CB-CB 4.21Å; K344-Q347 HydrophobicContact CB-CG 3.59Å; K344-Q347 VanDerWaalsContact CD-CD 3.47Å; K344-Q347 HydrophobicContact CD-CG 3.99Å; K344-Q347 HydrophobicContact CG-CG 4.44Å; K344-Q347 WeakPolarHBondContact O-CB 3.37Å; K344-Q347 PolarHBondContact O-N 3.11Å
348I97.6Very high98.3Very high10 Ų1011.8 Ų11.85%0.0516%0.059CC..Hα-helixtrans-102-33.1175.8-163.457.4000112.7K104 T324 N346 E353 S354K104-I348 WeakPolarHBondContact CD-O 3.46Å; K104-I348 WeakPolarHBondContact CE-O 3.38Å; K104-I348 PolarHBondContact NZ-O 2.84Å; T324-I348 HydrophobicContact CG2-CB 4.06Å; T324-I348 HydrophobicContact CG2-CG2 3.91Å; N346-I348 VanDerWaalsContact C-N 3.29Å; I348-E353 HydrophobicContact CB-CB 4.48Å; I348-E353 HydrophobicContact CD1-CB 4.48Å; I348-E353 HydrophobicContact CG1-CB 3.47Å; I348-E353 VanDerWaalsContact CG1-CB 3.47Å; I348-E353 HydrophobicContact CG1-CG 4.33Å; I348-E353 HydrophobicContact CG2-CB 4.19Å; I348-S354 WeakPolarHBondContact CG2-OG 3.42Å
349G97.1Very high98.3Very high0 Ų018.5 Ų18.50%09%0.088CC..  trans963.4165.500000116.8I112 L113 V345I112-G349 WeakPolarHBondContact CG2-O 3.33Å; L113-G349 WeakPolarHBondContact CA-O 3.27Å; L113-G349 PolarHBondContact N-O 3.29Å; V345-G349 PolarHBondContact O-N 3.46Å
350S98.8Very high98.3Very high0 Ų019.3 Ų19.30%09%0.092CC..SBendtrans-147.4156.3168.973.90000112.1E353 S354S350-E353 WeakPolarHBondContact CB-OE2 3.49Å; S350-E353 WeakPolarHBondContact OG-CB 3.37Å; S350-E353 VanDerWaalsContact OG-CG 3.3Å; S350-E353 WeakPolarHBondContact OG-CG 3.35Å; S350-E353 PolarHBondContact OG-N 3.42Å; S350-E353 VanDerWaalsContact OG-N 3.17Å; S350-E353 PolarHBondContact OG-OE2 3.01Å; S350-S354 WeakPolarHBondContact O-CB 3.43Å; S350-S354 PolarHBondContact O-N 3.14Å; S350-S354 VanDerWaalsContact O-N 3.16Å; S350-S354 PolarHBondContact O-OG 3.41Å
351V98.9Very high98.2Very high1 Ų119.3 Ų19.31%0.0069%0.092CC..Hα-helixtrans-62.6-47.1174.8174.50000109.9Q88 S116 L117 C120 E353 S354 L355 F381Q88-V351 HydrophobicContact CG-CB 4.38Å; Q88-V351 HydrophobicContact CG-CG1 4.28Å; S116-V351 WeakPolarHBondContact OG-CG2 3.25Å; S116-V351 PolarHBondContact OG-N 3.35Å; L117-V351 HydrophobicContact CD2-CG2 3.72Å; C120-V351 HydrophobicContact CB-CG2 4.3Å; V351-E353 PolarHBondContact O-N 2.9Å; V351-S354 WeakPolarHBondContact O-CB 3.47Å; V351-S354 PolarHBondContact O-N 2.94Å; V351-S354 VanDerWaalsContact O-N 3.11Å; V351-L355 HydrophobicContact CG1-CD1 4.15Å; V351-L355 HydrophobicContact CG1-CG 4.24Å; V351-L355 WeakPolarHBondContact O-CG 3.38Å; V351-L355 PolarHBondContact O-N 3.34Å; V351-F381 HydrophobicContact CG1-CZ 4.42Å; V351-F381 HydrophobicContact CG2-CE1 4.3Å; V351-F381 HydrophobicContact CG2-CZ 3.72Å
352T98.8Very high98.2Very high16 Ų1622.6 Ų22.610%0.09811%0.107CC..Hα-helixtrans-57.8-49.2-178.2-62.30000112.5E89 D92 S354 L355 Q356E89-T352 WeakPolarHBondContact CA-OG1 3.49Å; E89-T352 HydrophobicContact CB-CG2 4.1Å; E89-T352 HydrophobicContact CG-CG2 4.01Å; D92-T352 WeakPolarHBondContact OD2-CB 3.02Å; D92-T352 PolarHBondContact OD2-N 2.86Å; D92-T352 PolarHBondContact OD2-OG1 3.02Å; T352-S354 VanDerWaalsContact C-N 3.26Å; T352-S354 PolarHBondContact O-N 2.8Å; T352-L355 PolarHBondContact O-N 2.97Å; T352-Q356 WeakPolarHBondContact O-CG 3.45Å; T352-Q356 PolarHBondContact O-N 2.97Å
353E98.7Very high98.2Very high33 Ų3326.8 Ų26.815%0.15414%0.137CC..Hα-helixtrans-66.4-31.4178.7-66.7164107.700111.6L96 K104 I348 S350 V351 Q356 A357L96-E353 HydrophobicContact CD1-CG 4.28Å; K104-E353 WeakPolarHBondContact CE-OE2 3.45Å; K104-E353 IonicContact NZ-OE1 3.01Å; K104-E353 PolarHBondContact NZ-OE1 3.45Å; K104-E353 IonicContact NZ-OE2 3.03Å; K104-E353 PolarHBondContact NZ-OE2 2.85Å; I348-E353 HydrophobicContact CB-CB 4.48Å; I348-E353 HydrophobicContact CD1-CB 4.48Å; I348-E353 HydrophobicContact CG1-CB 3.47Å; I348-E353 VanDerWaalsContact CG1-CB 3.47Å; I348-E353 HydrophobicContact CG1-CG 4.33Å; I348-E353 HydrophobicContact CG2-CB 4.19Å; S350-E353 WeakPolarHBondContact CB-OE2 3.49Å; S350-E353 WeakPolarHBondContact OG-CB 3.37Å; S350-E353 VanDerWaalsContact OG-CG 3.3Å; S350-E353 WeakPolarHBondContact OG-CG 3.35Å; S350-E353 PolarHBondContact OG-N 3.42Å; S350-E353 VanDerWaalsContact OG-N 3.17Å; S350-E353 PolarHBondContact OG-OE2 3.01Å; V351-E353 PolarHBondContact O-N 2.9Å; E353-Q356 PolarHBondContact O-N 3.33Å; E353-A357 WeakPolarHBondContact O-CB 3.33Å; E353-A357 PolarHBondContact O-N 3.45Å
354S98.8Very high98.1Very high0 Ų030.4 Ų30.40%016%0.156CC..Hα-helixtrans-64.9-44.9173.7-57.50000112L343 I348 S350 V351 T352 Q356 A357 C358L343-S354 WeakPolarHBondContact CD1-O 3.36Å; I348-S354 WeakPolarHBondContact CG2-OG 3.42Å; S350-S354 WeakPolarHBondContact O-CB 3.43Å; S350-S354 PolarHBondContact O-N 3.14Å; S350-S354 VanDerWaalsContact O-N 3.16Å; S350-S354 PolarHBondContact O-OG 3.41Å; V351-S354 WeakPolarHBondContact O-CB 3.47Å; V351-S354 PolarHBondContact O-N 2.94Å; V351-S354 VanDerWaalsContact O-N 3.11Å; T352-S354 VanDerWaalsContact C-N 3.26Å; T352-S354 PolarHBondContact O-N 2.8Å; S354-Q356 VanDerWaalsContact C-N 3.3Å; S354-Q356 PolarHBondContact O-N 3.37Å; S354-A357 PolarHBondContact O-N 3.21Å; S354-C358 PolarHBondContact O-N 3.02Å
355L98.6Very high98.1Very high19 Ų1931 Ų3110%0.09917%0.165CC..Hα-helixtrans-60.6-41.9175.3-62.4175.8000110.9I135 L138 A139 V351 T352 C358 K359 L385 L389I135-L355 HydrophobicContact CG2-CD2 4.14Å; L138-L355 HydrophobicContact CB-CD1 3.67Å; L138-L355 HydrophobicContact CD1-CD1 4.38Å; A139-L355 HydrophobicContact CB-CD2 4.36Å; V351-L355 HydrophobicContact CG1-CD1 4.15Å; V351-L355 HydrophobicContact CG1-CG 4.24Å; V351-L355 WeakPolarHBondContact O-CG 3.38Å; V351-L355 PolarHBondContact O-N 3.34Å; T352-L355 PolarHBondContact O-N 2.97Å; L355-C358 PolarHBondContact O-N 3.34Å; L355-K359 WeakPolarHBondContact O-CB 3.42Å; L355-K359 PolarHBondContact O-N 3.05Å; L355-L385 HydrophobicContact CD2-CD1 4.35Å; L355-L389 HydrophobicContact CD2-CD2 3.36Å; L355-L389 HydrophobicContact CD2-CG 4.08Å
356Q98.5Very high98.1Very high96 Ų9631.5 Ų31.545%0.44917%0.167SC..Hα-helixtrans-65.6-42.2177.6-70171.5-4.600112.2T352 E353 S354 K359 L360T352-Q356 WeakPolarHBondContact O-CG 3.45Å; T352-Q356 PolarHBondContact O-N 2.97Å; E353-Q356 PolarHBondContact O-N 3.33Å; S354-Q356 VanDerWaalsContact C-N 3.3Å; S354-Q356 PolarHBondContact O-N 3.37Å; Q356-K359 PolarHBondContact O-N 3.48Å; Q356-L360 WeakPolarHBondContact O-CB 3.5Å; Q356-L360 PolarHBondContact O-N 2.96Å
357A98.7Very high98.2Very high0 Ų031 Ų310%017%0.165CC..Hα-helixtrans-61.8-44.3175.100000111.7T324 I329 L341 E353 S354 K359 L360 A361T324-A357 HydrophobicContact CG2-CB 3.99Å; I329-A357 HydrophobicContact CD1-CB 3.79Å; L341-A357 HydrophobicContact CD2-CB 4.31Å; E353-A357 WeakPolarHBondContact O-CB 3.33Å; E353-A357 PolarHBondContact O-N 3.45Å; S354-A357 PolarHBondContact O-N 3.21Å; A357-K359 PolarHBondContact O-N 3.33Å; A357-L360 PolarHBondContact O-N 2.68Å; A357-A361 PolarHBondContact O-N 2.53Å
358C98.6Very high98.4Very high0 Ų031 Ų310%017%0.165CC..Hα-helixtrans-57.9-49.5173.8-173.40000111.5L343 S354 L355 L360 A361 Q362 L389L343-C358 HydrophobicContact CD1-CB 3.62Å; S354-C358 PolarHBondContact O-N 3.02Å; L355-C358 PolarHBondContact O-N 3.34Å; C358-L360 VanDerWaalsContact C-N 3.34Å; C358-L360 PolarHBondContact O-N 3.43Å; C358-A361 PolarHBondContact O-N 2.9Å; C358-Q362 WeakPolarHBondContact O-CG 3.35Å; C358-Q362 PolarHBondContact O-N 3.4Å; C358-Q362 VanDerWaalsContact SG-CD 3.56Å; C358-Q362 PolarHBondContact SG-OE1 3.26Å; C358-Q362 VanDerWaalsContact SG-OE1 3.33Å; C358-L389 HydrophobicContact CB-CD1 3.98Å; C358-L389 HydrophobicContact CB-CD2 4.05Å
359K98.1Very high98.5Very high145 Ų14530.6 Ų30.663%0.6316%0.163SC*.Hα-helixtrans-62.2-40.5179.9-174.6174.6-177.4173.50112.1L355 Q356 A357 S363L355-K359 WeakPolarHBondContact O-CB 3.42Å; L355-K359 PolarHBondContact O-N 3.05Å; Q356-K359 PolarHBondContact O-N 3.48Å; A357-K359 PolarHBondContact O-N 3.33Å; K359-S363 VanDerWaalsContact O-CB 3.25Å; K359-S363 WeakPolarHBondContact O-CB 3.27Å; K359-S363 PolarHBondContact O-N 3.47Å; K359-S363 PolarHBondContact O-OG 3.11Å
360L98.4Very high98.5Very high49 Ų4930.6 Ų30.626%0.25716%0.163SC..Hα-helixtrans-60.5-45.9175.6178.161.5000111.1P326 I329 Q356 A357 C358 S363 N364P326-L360 HydrophobicContact CB-CD2 4.29Å; I329-L360 HydrophobicContact CB-CD2 3.94Å; I329-L360 HydrophobicContact CG2-CD2 3.63Å; I329-L360 HydrophobicContact CG2-CG 3.83Å; Q356-L360 WeakPolarHBondContact O-CB 3.5Å; Q356-L360 PolarHBondContact O-N 2.96Å; A357-L360 PolarHBondContact O-N 2.68Å; C358-L360 VanDerWaalsContact C-N 3.34Å; C358-L360 PolarHBondContact O-N 3.43Å; L360-S363 PolarHBondContact O-OG 2.77Å; L360-S363 VanDerWaalsContact O-OG 3.11Å; L360-N364 PolarHBondContact O-N 3.29Å; L360-N364 PolarHBondContact O-ND2 2.63Å
361A98.6Very high98.5Very high0 Ų030.8 Ų30.80%016%0.164CC..Hα-helixtrans-63.4-53.5176.700000111.7L341 A357 C358 S363 N364 G365 W366 V368L341-A361 HydrophobicContact CB-CB 3.92Å; L341-A361 HydrophobicContact CD2-CB 4Å; A357-A361 PolarHBondContact O-N 2.53Å; C358-A361 PolarHBondContact O-N 2.9Å; A361-S363 PolarHBondContact O-N 2.92Å; A361-N364 CarbonylContact O-C 3.56Å; A361-N364 PolarHBondContact O-N 3Å; A361-N364 VanDerWaalsContact O-N 3.07Å; A361-G365 PolarHBondContact O-N 3.38Å; A361-W366 HydrophobicContact CB-CB 4.06Å; A361-W366 HydrophobicContact CB-CE3 4.32Å; A361-W366 WeakPolarHBondContact O-CB 3.41Å; A361-W366 PolarHBondContact O-N 2.97Å; A361-V368 HydrophobicContact CB-CG2 3.66Å
362Q98.2Very high98.5Very high68 Ų6830.9 Ų30.932%0.31816%0.164SC..Hα-helixtrans-61.6-41.5-176.9-73.5172.3-39.800112.6C358 N364 G365 V368 L389C358-Q362 WeakPolarHBondContact O-CG 3.35Å; C358-Q362 PolarHBondContact O-N 3.4Å; C358-Q362 VanDerWaalsContact SG-CD 3.56Å; C358-Q362 PolarHBondContact SG-OE1 3.26Å; C358-Q362 VanDerWaalsContact SG-OE1 3.33Å; Q362-N364 PolarHBondContact O-N 3.47Å; Q362-G365 PolarHBondContact O-N 3.37Å; Q362-V368 HydrophobicContact CG-CG2 3.9Å; Q362-L389 PolarHBondContact NE2-O 2.95Å
363S97.6Very high98.3Very high89 Ų8930.4 Ų30.462%0.62216%0.161SC*.Hα-helixtrans-65.2-20.7177.258.90000113.9K359 L360 A361 G365K359-S363 VanDerWaalsContact O-CB 3.25Å; K359-S363 WeakPolarHBondContact O-CB 3.27Å; K359-S363 PolarHBondContact O-N 3.47Å; K359-S363 PolarHBondContact O-OG 3.11Å; L360-S363 PolarHBondContact O-OG 2.77Å; L360-S363 VanDerWaalsContact O-OG 3.11Å; A361-S363 PolarHBondContact O-N 2.92Å; S363-G365 VanDerWaalsContact C-N 3.34Å
364N98.3Very high98Very high76 Ų7629 Ų2941%0.40616%0.155SC..THydrogen-bonded Turntrans-95.713.8172.3-72.9-77.9000112.8V333 L360 A361 Q362 W366V333-N364 HydrophobicContact CG1-CB 3.85Å; V333-N364 WeakPolarHBondContact CG1-OD1 3.24Å; V333-N364 HydrophobicContact CG2-CB 3.81Å; L360-N364 PolarHBondContact O-N 3.29Å; L360-N364 PolarHBondContact O-ND2 2.63Å; A361-N364 CarbonylContact O-C 3.56Å; A361-N364 PolarHBondContact O-N 3Å; A361-N364 VanDerWaalsContact O-N 3.07Å; Q362-N364 PolarHBondContact O-N 3.47Å; N364-W366 VanDerWaalsContact C-N 3.29Å; N364-W366 PolarHBondContact O-N 3.22Å
365G97.6Very high97.8Very high24 Ų2429 Ų2925%0.24716%0.155CC..THydrogen-bonded Turntrans75.213177.300000114.3A361 Q362 S363 R431A361-G365 PolarHBondContact O-N 3.38Å; Q362-G365 PolarHBondContact O-N 3.37Å; S363-G365 VanDerWaalsContact C-N 3.34Å; G365-R431 PolarHBondContact O-NE 3.35Å; G365-R431 PolarHBondContact O-NH2 3.16Å
366W98.6Very high97.8Very high19 Ų1928.4 Ų28.47%0.07215%0.152CC..  trans-79151.5174.2-70.512.4000111.4T322 I329 G332 V333 C338 N339 L341 A361 N364T322-W366 HydrophobicContact CG2-CZ3 4.38Å; I329-W366 HydrophobicContact CG2-CZ3 4.25Å; G332-W366 WeakPolarHBondContact O-CZ2 3.35Å; V333-W366 HydrophobicContact CB-CZ2 4.26Å; V333-W366 HydrophobicContact CG2-CD2 4.2Å; V333-W366 HydrophobicContact CG2-CH2 4.01Å; V333-W366 HydrophobicContact CG2-CZ2 3.63Å; V333-W366 HydrophobicContact CG2-CZ3 4.45Å; C338-W366 WeakPolarHBondContact O-CZ2 3.4Å; C338-W366 PolarHBondContact O-NE1 3.11Å; C338-W366 WeakPolarHBondContact SG-CH2 3.37Å; C338-W366 WeakPolarHBondContact SG-CZ3 3.38Å; N339-W366 VanDerWaalsContact O-CA 3.29Å; N339-W366 WeakPolarHBondContact O-CA 3.42Å; L341-W366 HydrophobicContact CB-CE3 4.42Å; A361-W366 HydrophobicContact CB-CB 4.06Å; A361-W366 HydrophobicContact CB-CE3 4.32Å; A361-W366 WeakPolarHBondContact O-CB 3.41Å; A361-W366 PolarHBondContact O-N 2.97Å; N364-W366 VanDerWaalsContact C-N 3.29Å; N364-W366 PolarHBondContact O-N 3.22Å
367G98.8Very high97.8Very high4 Ų424 Ų244%0.04113%0.131CC..EExtended strand (participates in β ladder)trans-70.4164.516000000111N339 C340 L341 R430N339-G367 PolarHBondContact O-N 2.84Å; C340-G367 CarbonylContact C-O 3.56Å; C340-G367 VanDerWaalsContact CA-O 3.25Å; C340-G367 WeakPolarHBondContact CA-O 3.5Å; C340-G367 VanDerWaalsContact SG-C 3.5Å; C340-G367 PolarHBondContact SG-O 3.08Å; L341-G367 PolarHBondContact N-O 3.49Å; G367-R430 WeakPolarHBondContact CA-O 3.02Å
368V98.9Very high97.8Very high1 Ų130.1 Ų30.11%0.00616%0.16CC..EExtended strand (participates in β ladder)trans-133.5125.4169.6-1790000108.1L341 L343 A361 Q362 T391 Q393L341-V368 HydrophobicContact CB-CG2 4.34Å; L341-V368 HydrophobicContact CD2-CG1 4.41Å; L341-V368 CarbonylContact O-C 3.54Å; L341-V368 WeakPolarHBondContact O-CA 3.42Å; L343-V368 HydrophobicContact CB-CG1 3.72Å; L343-V368 HydrophobicContact CD1-CG1 3.91Å; L343-V368 HydrophobicContact CG-CG1 4.48Å; A361-V368 HydrophobicContact CB-CG2 3.66Å; Q362-V368 HydrophobicContact CG-CG2 3.9Å; V368-T391 HydrophobicContact CB-CG2 3.98Å; V368-T391 HydrophobicContact CG1-CG2 3.99Å; V368-T391 WeakPolarHBondContact O-CB 3.14Å; V368-T391 PolarHBondContact O-OG1 3.44Å; V368-Q393 VanDerWaalsContact O-CG 3.22Å; V368-Q393 WeakPolarHBondContact O-CG 3.42Å
369M98.9Very high97.8Very high2 Ų231 Ų311%0.0116%0.164CC..EExtended strand (participates in β ladder)trans-107.2109.8173.3-176.2-176.9-63.400108.6L341 L342 L343 S371 Q393 K395L341-M369 PolarHBondContact O-N 2.83Å; L342-M369 WeakPolarHBondContact CA-O 3.33Å; L342-M369 HydrophobicContact CD1-CB 3.9Å; L342-M369 HydrophobicContact CD1-CG 3.87Å; L342-M369 HydrophobicContact CD1-SD 3.8Å; L343-M369 PolarHBondContact N-O 2.94Å; M369-S371 PolarHBondContact O-N 3.32Å; M369-Q393 HydrophobicContact CB-CG 4.04Å; M369-Q393 HydrophobicContact CG-CG 4.35Å; M369-K395 HydrophobicContact CG-CB 4.12Å; M369-K395 HydrophobicContact SD-CB 3.6Å; M369-K395 VanDerWaalsContact SD-CB 3.6Å; M369-K395 HydrophobicContact SD-CD 4.35Å
370V98.9Very high97.8Very high0 Ų025.8 Ų25.80%015%0.145CC..EExtended strand (participates in β ladder)trans-67.3134.8173175.60000108.2L343 I382 L385 V386 T391 Q393 I394 K395L343-V370 HydrophobicContact CD2-CG2 4.49Å; V370-I382 HydrophobicContact CG1-CB 3.85Å; V370-I382 HydrophobicContact CG1-CG2 4.33Å; V370-L385 HydrophobicContact CG1-CD2 4.15Å; V370-V386 HydrophobicContact CB-CB 3.86Å; V370-V386 HydrophobicContact CB-CG2 4.01Å; V370-V386 HydrophobicContact CG1-CB 4.29Å; V370-V386 HydrophobicContact CG2-CB 3.76Å; V370-V386 HydrophobicContact CG2-CG2 3.88Å; V370-T391 HydrophobicContact CG2-CG2 3.95Å; V370-Q393 PolarHBondContact N-O 3.03Å; V370-I394 HydrophobicContact CB-CG1 4.49Å; V370-I394 WeakPolarHBondContact O-CA 3.35Å; V370-I394 WeakPolarHBondContact O-CG1 3.36Å; V370-K395 PolarHBondContact O-N 3.48Å
371S98.8Very high97.9Very high4 Ų423.8 Ų23.83%0.02813%0.134CC..EExtended strand (participates in β ladder)trans-126.7145.4-173.4-177.60000112.9L343 M369 K395L343-S371 PolarHBondContact O-N 3.04Å; M369-S371 PolarHBondContact O-N 3.32Å; S371-K395 WeakPolarHBondContact CA-O 3.32Å
372H97.8Very high97.9Very high3 Ų324.1 Ų24.11%0.01414%0.136CC..  trans-70-174.6159.969170.9000112.4E211 E376 I382 K395 T396 G397 R404E211-H372 IonicContact OE1-CE1 3.03Å; E211-H372 IonicContact OE1-NE2 2.71Å; E211-H372 IonicContact OE2-CE1 2.7Å; E211-H372 PolarHBondContact OE2-CE1 2.95Å; E211-H372 IonicContact OE2-NE2 3.2Å; E211-H372 PolarHBondContact OE2-NE2 2.98Å; H372-E376 HydrophobicContact CB-CG 3.85Å; H372-I382 HydrophobicContact CB-CD1 3.97Å; H372-K395 PolarHBondContact CD2-O 3.47Å; H372-K395 PolarHBondContact N-O 3.26Å; H372-T396 WeakPolarHBondContact ND1-CA 3.09Å; H372-G397 VanDerWaalsContact CE1-CA 3.44Å; H372-G397 WeakPolarHBondContact CE1-CA 3.32Å; H372-G397 PolarHBondContact CE1-N 2.94Å; H372-G397 PolarHBondContact ND1-N 2.89Å; H372-R404 PolarHBondContact ND1-NH1 3.45Å; H372-R404 VanDerWaalsContact ND1-NH1 3.13Å
373R95.4Very high97.9Very high7 Ų720.9 Ų20.93%0.02612%0.121CC..  trans-120.3165.7158-54.7-63.7-66.5-102.113.5110.6P37 S38 S41 E46 N346 G375 E376 R404P37-R373 HydrophobicContact CB-CB 4.09Å; P37-R373 HydrophobicContact CB-CG 3.98Å; P37-R373 HydrophobicContact CG-CG 4.08Å; S38-R373 WeakPolarHBondContact O-CB 3.48Å; S41-R373 PolarHBondContact O-NH2 3.1Å; E46-R373 IonicContact OE1-CZ 3.79Å; E46-R373 IonicContact OE1-NH1 3.3Å; E46-R373 IonicContact OE1-NH2 3.91Å; E46-R373 PolarHBondContact OE1-NH2 2.87Å; E46-R373 IonicContact OE2-CZ 3.59Å; E46-R373 IonicContact OE2-NH1 3.96Å; E46-R373 PolarHBondContact OE2-NH1 3.28Å; E46-R373 IonicContact OE2-NH2 2.93Å; E46-R373 PolarHBondContact OE2-NH2 3.06Å; N346-R373 VanDerWaalsContact CG-NH1 3.26Å; N346-R373 PolarHBondContact ND2-NH1 3.37Å; N346-R373 VanDerWaalsContact OD1-CD 3.31Å; N346-R373 WeakPolarHBondContact OD1-CD 3.46Å; N346-R373 WeakPolarHBondContact OD1-CG 3.02Å; N346-R373 PolarHBondContact OD1-NH1 3.45Å; R373-G375 VanDerWaalsContact C-N 3.34Å; R373-G375 PolarHBondContact O-N 3.33Å; R373-E376 WeakPolarHBondContact O-CG 3.47Å; R373-R404 PolarHBondContact O-NH1 2.92Å
374S91.7Very high98Very high4 Ų417 Ų173%0.0289%0.093CC..SBendtrans-62.1-37.1175.953.30000113S15 A40 R404S15-S374 PolarHBondContact OG-O 3.35Å; A40-S374 WeakPolarHBondContact CB-OG 3.14Å; A40-S374 PolarHBondContact N-OG 2.89Å; S374-R404 PolarHBondContact O-NH2 3.12Å
375G94.8Very high98Very high0 Ų013.4 Ų13.40%07%0.074CC..BIsolated β-bridgetrans-92.786.6166.300000111.5D14 P37 S38 R373D14-G375 WeakPolarHBondContact OD2-CA 3.37Å; P37-G375 CarbonylContact C-O 3.56Å; P37-G375 VanDerWaalsContact CA-O 3.31Å; P37-G375 WeakPolarHBondContact CA-O 3.35Å; P37-G375 WeakPolarHBondContact CB-O 3.46Å; S38-G375 PolarHBondContact N-O 3.04Å; S38-G375 CarbonylContact O-C 3.59Å; S38-G375 WeakPolarHBondContact O-CA 3.17Å; S38-G375 PolarHBondContact O-N 2.99Å; R373-G375 VanDerWaalsContact C-N 3.34Å; R373-G375 PolarHBondContact O-N 3.33Å
376E98.1Very high98.1Very high6 Ų612.2 Ų12.23%0.0286%0.062CC..  trans-93.7172.9177.1-104-68.6179.300112.6D14 S15 H372 R373 E403 R404 K407D14-E376 CarbonylContact C-O 3.59Å; D14-E376 WeakPolarHBondContact CA-O 3.43Å; S15-E376 WeakPolarHBondContact CB-O 3.48Å; S15-E376 PolarHBondContact N-O 3.09Å; S15-E376 PolarHBondContact OG-N 3.01Å; S15-E376 VanDerWaalsContact OG-N 3.07Å; S15-E376 PolarHBondContact OG-O 3.17Å; H372-E376 HydrophobicContact CB-CG 3.85Å; R373-E376 WeakPolarHBondContact O-CG 3.47Å; E376-E403 HydrophobicContact CB-CB 3.9Å; E376-E403 HydrophobicContact CB-CG 3.67Å; E376-R404 VanDerWaalsContact CB-NH1 3.34Å; E376-K407 WeakPolarHBondContact OE1-CE 3.28Å; E376-K407 IonicContact OE1-NZ 3.43Å; E376-K407 WeakPolarHBondContact OE2-CE 3.3Å; E376-K407 IonicContact OE2-NZ 2.84Å; E376-K407 PolarHBondContact OE2-NZ 3.45Å
377T98.8Very high98.1Very high3 Ų311.3 Ų11.32%0.0186%0.058CC..  trans-121.6-178.7173.8680000110T20 A35 D379 E403 K407T20-T377 HydrophobicContact CG2-CG2 3.89Å; A35-T377 HydrophobicContact CB-CG2 3.92Å; T377-D379 PolarHBondContact O-N 2.71Å; T377-D379 VanDerWaalsContact OG1-CB 3.28Å; T377-D379 WeakPolarHBondContact OG1-CB 3.34Å; T377-D379 PolarHBondContact OG1-N 2.98Å; T377-E403 WeakPolarHBondContact O-CB 3.28Å; T377-K407 PolarHBondContact O-NZ 2.92Å
378E98.6Very high98.1Very high128 Ų12811.1 Ų11.160%0.5986%0.056SC*.SBendtrans-73-8169.766.5-92.7-124.600113.7
379D98.8Very high98.1Very high18 Ų1811.2 Ų11.210%0.0966%0.057CC..  trans-60.4137.7178.4-161.7-43.9000110.5A34 A35 K121 T377 F381 K407A34-D379 WeakPolarHBondContact CA-OD2 3.48Å; A35-D379 HydrophobicContact CB-CB 4.32Å; A35-D379 PolarHBondContact N-OD2 3.14Å; K121-D379 IonicContact NZ-OD1 3.35Å; K121-D379 PolarHBondContact NZ-OD1 2.62Å; K121-D379 IonicContact NZ-OD2 3.47Å; K121-D379 PolarHBondContact NZ-OD2 3.45Å; T377-D379 PolarHBondContact O-N 2.71Å; T377-D379 VanDerWaalsContact OG1-CB 3.28Å; T377-D379 WeakPolarHBondContact OG1-CB 3.34Å; T377-D379 PolarHBondContact OG1-N 2.98Å; D379-F381 WeakPolarHBondContact OD1-CB 3.32Å; D379-F381 PolarHBondContact OD1-N 3.09Å; D379-K407 WeakPolarHBondContact O-CD 3.49Å; D379-K407 WeakPolarHBondContact O-CE 3.3Å; D379-K407 PolarHBondContact O-NZ 3.41Å
380T98.9Very high98.1Very high36 Ų3611.3 Ų11.322%0.2216%0.058CC..  trans-106.89-176.153.20000113.6I382 A383 A406 Q410T380-I382 VanDerWaalsContact C-N 3.26Å; T380-I382 PolarHBondContact O-N 2.85Å; T380-A383 VanDerWaalsContact O-CB 3.26Å; T380-A383 WeakPolarHBondContact O-CB 3.44Å; T380-A383 PolarHBondContact O-N 3.38Å; T380-A406 HydrophobicContact CG2-CB 3.77Å; T380-A406 VanDerWaalsContact CG2-O 3.26Å; T380-A406 WeakPolarHBondContact CG2-O 3.46Å; T380-Q410 HydrophobicContact CG2-CB 4.04Å
381F98.9Very high98.1Very high7 Ų711.4 Ų11.43%0.0316%0.058CC..Hα-helixtrans-47.5-43.4-172.5-173.2-88.8000114.4L117 C120 L131 I135 V351 D379 A383 D384 L385L117-F381 HydrophobicContact CB-CD2 4.4Å; L117-F381 HydrophobicContact CB-CE2 4.44Å; L117-F381 HydrophobicContact CD2-CD1 3.46Å; L117-F381 VanDerWaalsContact CD2-CD1 3.46Å; L117-F381 HydrophobicContact CD2-CD2 3.73Å; L117-F381 HydrophobicContact CD2-CE1 3.35Å; L117-F381 HydrophobicContact CD2-CE2 3.63Å; L117-F381 HydrophobicContact CD2-CG 3.66Å; L117-F381 HydrophobicContact CD2-CZ 3.44Å; L117-F381 VanDerWaalsContact CD2-CZ 3.44Å; C120-F381 HydrophobicContact CB-CE2 3.99Å; C120-F381 HydrophobicContact CB-CZ 4.34Å; L131-F381 HydrophobicContact CD1-CE2 4.31Å; L131-F381 HydrophobicContact CD2-CD2 3.79Å; L131-F381 HydrophobicContact CD2-CE2 4.1Å; I135-F381 HydrophobicContact CD1-CE1 4.38Å; I135-F381 HydrophobicContact CD1-CE2 4.27Å; I135-F381 HydrophobicContact CD1-CZ 3.95Å; V351-F381 HydrophobicContact CG1-CZ 4.42Å; V351-F381 HydrophobicContact CG2-CE1 4.3Å; V351-F381 HydrophobicContact CG2-CZ 3.72Å; D379-F381 WeakPolarHBondContact OD1-CB 3.32Å; D379-F381 PolarHBondContact OD1-N 3.09Å; F381-A383 PolarHBondContact O-N 2.88Å; F381-D384 PolarHBondContact O-N 3.22Å; F381-D384 VanDerWaalsContact O-N 3.16Å; F381-L385 HydrophobicContact CD1-CB 4.22Å; F381-L385 HydrophobicContact CD1-CD2 4.49Å; F381-L385 HydrophobicContact CE1-CB 4.12Å; F381-L385 HydrophobicContact CE1-CD1 4.07Å; F381-L385 HydrophobicContact CE1-CD2 4.21Å; F381-L385 HydrophobicContact CE1-CG 4.36Å; F381-L385 WeakPolarHBondContact O-CB 3.39Å; F381-L385 PolarHBondContact O-N 3.28Å
382I98.9Very high98.1Very high8 Ų811.2 Ų11.24%0.0416%0.057CC..Hα-helixtrans-67.8-20-176.563.5171.2000113.8V370 H372 T380 L385 V386 I394 K407V370-I382 HydrophobicContact CG1-CB 3.85Å; V370-I382 HydrophobicContact CG1-CG2 4.33Å; H372-I382 HydrophobicContact CB-CD1 3.97Å; T380-I382 VanDerWaalsContact C-N 3.26Å; T380-I382 PolarHBondContact O-N 2.85Å; I382-L385 HydrophobicContact CG2-CD2 4.47Å; I382-V386 WeakPolarHBondContact O-CG1 3.2Å; I382-V386 PolarHBondContact O-N 3.22Å; I382-I394 HydrophobicContact CD1-CD1 4.49Å; I382-I394 HydrophobicContact CG1-CD1 4.42Å; I382-K407 HydrophobicContact CD1-CG 4.02Å; I382-K407 HydrophobicContact CG1-CG 3.58Å
383A98.9Very high98.1Very high0 Ų011 Ų110%06%0.056CC..Hα-helixtrans-69.5-44.1171.700000111.5T380 F381 L385 V386 V387 K407 Q410 L411T380-A383 VanDerWaalsContact O-CB 3.26Å; T380-A383 WeakPolarHBondContact O-CB 3.44Å; T380-A383 PolarHBondContact O-N 3.38Å; F381-A383 PolarHBondContact O-N 2.88Å; A383-L385 VanDerWaalsContact C-N 3.35Å; A383-V386 VanDerWaalsContact O-CG1 3.27Å; A383-V386 WeakPolarHBondContact O-CG1 3.33Å; A383-V387 WeakPolarHBondContact O-CG2 3.36Å; A383-K407 HydrophobicContact CB-CB 4.21Å; A383-K407 WeakPolarHBondContact CB-O 3.45Å; A383-Q410 HydrophobicContact CB-CB 3.74Å; A383-Q410 HydrophobicContact CB-CG 3.67Å; A383-L411 HydrophobicContact CB-CD2 4.12Å; A383-L411 HydrophobicContact CB-CG 3.89Å; A383-L411 WeakPolarHBondContact O-CD2 3.47Å
384D98.9Very high98.3Very high6 Ų610.7 Ų10.73%0.0326%0.055CC..Hα-helixtrans-69.3-36.1172.9-74.8-100.3000111.6L131 Y132 I135 F381 V387 G388 Q410L131-D384 HydrophobicContact CB-CB 4.06Å; L131-D384 WeakPolarHBondContact CB-OD1 3.49Å; L131-D384 HydrophobicContact CD2-CB 3.75Å; L131-D384 HydrophobicContact CG-CB 3.74Å; Y132-D384 WeakPolarHBondContact CA-O 3.25Å; Y132-D384 WeakPolarHBondContact CB-O 3.45Å; Y132-D384 WeakPolarHBondContact CD1-OD1 3.33Å; Y132-D384 PolarHBondContact N-OD1 3.5Å; I135-D384 HydrophobicContact CD1-CB 4.24Å; F381-D384 PolarHBondContact O-N 3.22Å; F381-D384 VanDerWaalsContact O-N 3.16Å; D384-V387 PolarHBondContact O-N 3.16Å; D384-G388 PolarHBondContact O-N 3.37Å; D384-Q410 WeakPolarHBondContact OD2-CG 2.92Å; D384-Q410 PolarHBondContact OD2-NE2 2.67Å
385L98.9Very high98.6Very high1 Ų110.6 Ų10.61%0.0055%0.054CC..Hα-helixtrans-61-50.2178.4-175.466.6000112.4I135 L343 V345 L355 V370 F381 I382 A383 V387 G388 L389I135-L385 HydrophobicContact CD1-CB 4.3Å; I135-L385 HydrophobicContact CD1-CD1 4.25Å; I135-L385 HydrophobicContact CG2-CD1 3.93Å; L343-L385 HydrophobicContact CD2-CD2 3.94Å; V345-L385 HydrophobicContact CG1-CD2 3.37Å; L355-L385 HydrophobicContact CD2-CD1 4.35Å; V370-L385 HydrophobicContact CG1-CD2 4.15Å; F381-L385 HydrophobicContact CD1-CB 4.22Å; F381-L385 HydrophobicContact CD1-CD2 4.49Å; F381-L385 HydrophobicContact CE1-CB 4.12Å; F381-L385 HydrophobicContact CE1-CD1 4.07Å; F381-L385 HydrophobicContact CE1-CD2 4.21Å; F381-L385 HydrophobicContact CE1-CG 4.36Å; F381-L385 WeakPolarHBondContact O-CB 3.39Å; F381-L385 PolarHBondContact O-N 3.28Å; I382-L385 HydrophobicContact CG2-CD2 4.47Å; A383-L385 VanDerWaalsContact C-N 3.35Å; L385-V387 VanDerWaalsContact C-N 3.28Å; L385-V387 PolarHBondContact O-N 2.75Å; L385-G388 PolarHBondContact O-N 3.43Å; L385-L389 HydrophobicContact CD1-CD1 3.7Å; L385-L389 HydrophobicContact CD1-CG 3.99Å; L385-L389 HydrophobicContact CD2-CD1 4.44Å; L385-L389 HydrophobicContact CG-CD1 3.78Å; L385-L389 HydrophobicContact CG-CG 4.33Å; L385-L389 VanDerWaalsContact O-CB 3.26Å; L385-L389 WeakPolarHBondContact O-CB 3.35Å; L385-L389 WeakPolarHBondContact O-CG 3.18Å; L385-L389 PolarHBondContact O-N 3.29Å
386V98.9Very high98.8Very high0 Ų010.6 Ų10.60%05%0.054CC..Hα-helixtrans-63.2-36.9-177.866.70000112.1P147 V370 I382 A383 C390 T391 Q393 I394 L411P147-V386 HydrophobicContact CB-CG1 4.38Å; P147-V386 HydrophobicContact CB-CG2 3.71Å; P147-V386 HydrophobicContact CG-CG1 3.74Å; P147-V386 HydrophobicContact CG-CG2 4.03Å; V370-V386 HydrophobicContact CB-CB 3.86Å; V370-V386 HydrophobicContact CB-CG2 4.01Å; V370-V386 HydrophobicContact CG1-CB 4.29Å; V370-V386 HydrophobicContact CG2-CB 3.76Å; V370-V386 HydrophobicContact CG2-CG2 3.88Å; I382-V386 WeakPolarHBondContact O-CG1 3.2Å; I382-V386 PolarHBondContact O-N 3.22Å; A383-V386 VanDerWaalsContact O-CG1 3.27Å; A383-V386 WeakPolarHBondContact O-CG1 3.33Å; V386-C390 PolarHBondContact O-N 2.97Å; V386-C390 VanDerWaalsContact O-N 3.17Å; V386-T391 VanDerWaalsContact CG2-OG1 3.27Å; V386-T391 WeakPolarHBondContact CG2-OG1 3.39Å; V386-T391 PolarHBondContact O-N 2.94Å; V386-Q393 WeakPolarHBondContact CG2-O 3.44Å; V386-I394 HydrophobicContact CB-CB 4.41Å; V386-I394 HydrophobicContact CB-CD1 4.33Å; V386-I394 HydrophobicContact CG1-CB 4.27Å; V386-I394 HydrophobicContact CG1-CD1 3.85Å; V386-I394 HydrophobicContact CG2-CB 4.06Å; V386-L411 HydrophobicContact CG1-CD2 3.94Å
387V98.9Very high98.8Very high0 Ų010.3 Ų10.30%05%0.052CC..Hα-helixtrans-69.5-47.3176.71750000110.5Y132 V144 I145 L146 A383 D384 L385 L389 C390 L411 I414Y132-V387 HydrophobicContact CD2-CG1 4.08Å; Y132-V387 HydrophobicContact CG-CG1 4.13Å; V144-V387 HydrophobicContact CB-CG1 3.75Å; V144-V387 HydrophobicContact CG1-CG1 4.29Å; V144-V387 HydrophobicContact CG2-CG1 4.16Å; I145-V387 WeakPolarHBondContact O-CA 3.45Å; L146-V387 HydrophobicContact CD1-CG2 4.1Å; A383-V387 WeakPolarHBondContact O-CG2 3.36Å; D384-V387 PolarHBondContact O-N 3.16Å; L385-V387 VanDerWaalsContact C-N 3.28Å; L385-V387 PolarHBondContact O-N 2.75Å; V387-L389 PolarHBondContact O-N 3.35Å; V387-C390 PolarHBondContact O-N 3.28Å; V387-C390 VanDerWaalsContact O-N 3.16Å; V387-L411 HydrophobicContact CG2-CD2 3.56Å; V387-I414 HydrophobicContact CG1-CG2 4Å; V387-I414 HydrophobicContact CG2-CD1 4.31Å; V387-I414 HydrophobicContact CG2-CG2 4.14Å
388G98.8Very high98.8Very high0 Ų010.2 Ų10.20%05%0.052CC..Hα-helixtrans-65-37.5-179.800000113.3Y132 A136 N141 D384 L385 C390Y132-G388 VanDerWaalsContact O-CA 3.27Å; Y132-G388 WeakPolarHBondContact O-CA 3.17Å; A136-G388 WeakPolarHBondContact CA-O 3.34Å; A136-G388 WeakPolarHBondContact CB-O 3.19Å; N141-G388 PolarHBondContact ND2-O 3.33Å; D384-G388 PolarHBondContact O-N 3.37Å; L385-G388 PolarHBondContact O-N 3.43Å; G388-C390 VanDerWaalsContact C-N 3.26Å; G388-C390 PolarHBondContact O-N 3.21Å
389L98.8Very high98.8Very high3 Ų34.8 Ų4.82%0.0163%0.028CC..THydrogen-bonded Turntrans-77.4-9.3175.8-76-178.8000114.1I135 A139 N141 L343 L355 C358 Q362 L385 V387 T391I135-L389 HydrophobicContact CG2-CG 4.49Å; A139-L389 HydrophobicContact CB-CD2 3.94Å; N141-L389 PolarHBondContact ND2-O 3.41Å; L343-L389 HydrophobicContact CD1-CD1 4.23Å; L355-L389 HydrophobicContact CD2-CD2 3.36Å; L355-L389 HydrophobicContact CD2-CG 4.08Å; C358-L389 HydrophobicContact CB-CD1 3.98Å; C358-L389 HydrophobicContact CB-CD2 4.05Å; Q362-L389 PolarHBondContact NE2-O 2.95Å; L385-L389 HydrophobicContact CD1-CD1 3.7Å; L385-L389 HydrophobicContact CD1-CG 3.99Å; L385-L389 HydrophobicContact CD2-CD1 4.44Å; L385-L389 HydrophobicContact CG-CD1 3.78Å; L385-L389 HydrophobicContact CG-CG 4.33Å; L385-L389 VanDerWaalsContact O-CB 3.26Å; L385-L389 WeakPolarHBondContact O-CB 3.35Å; L385-L389 WeakPolarHBondContact O-CG 3.18Å; L385-L389 PolarHBondContact O-N 3.29Å; V387-L389 PolarHBondContact O-N 3.35Å; L389-T391 HydrophobicContact CB-CG2 3.43Å; L389-T391 VanDerWaalsContact CB-CG2 3.43Å; L389-T391 HydrophobicContact CD1-CG2 4.26Å; L389-T391 HydrophobicContact CG-CG2 4.49Å; L389-T391 PolarHBondContact O-N 3.25Å
390C98.6Very high98.8Very high4 Ų45.5 Ų5.53%0.0273%0.034CC..THydrogen-bonded Turntrans53.138.7-178.3-59.10000113.3D143 V144 I145 V386 V387 G388 G392 P432 I433D143-C390 PolarHBondContact O-SG 3.3Å; V144-C390 VanDerWaalsContact CA-SG 3.57Å; I145-C390 HydrophobicContact CG2-CB 4.4Å; V386-C390 PolarHBondContact O-N 2.97Å; V386-C390 VanDerWaalsContact O-N 3.17Å; V387-C390 PolarHBondContact O-N 3.28Å; V387-C390 VanDerWaalsContact O-N 3.16Å; G388-C390 VanDerWaalsContact C-N 3.26Å; G388-C390 PolarHBondContact O-N 3.21Å; C390-G392 VanDerWaalsContact C-N 3.31Å; C390-G392 PolarHBondContact O-N 3.11Å; C390-P432 WeakPolarHBondContact O-CG 3.18Å; C390-I433 HydrophobicContact CB-CD1 3.46Å; C390-I433 VanDerWaalsContact CB-CD1 3.46Å; C390-I433 HydrophobicContact CB-CG1 4.34Å
391T98.8Very high98.7Very high1 Ų17.7 Ų7.71%0.0064%0.038CC..  trans-79.3-19.7-17284.10000113.2V368 V370 V386 L389 Q393V368-T391 HydrophobicContact CB-CG2 3.98Å; V368-T391 HydrophobicContact CG1-CG2 3.99Å; V368-T391 WeakPolarHBondContact O-CB 3.14Å; V368-T391 PolarHBondContact O-OG1 3.44Å; V370-T391 HydrophobicContact CG2-CG2 3.95Å; V386-T391 VanDerWaalsContact CG2-OG1 3.27Å; V386-T391 WeakPolarHBondContact CG2-OG1 3.39Å; V386-T391 PolarHBondContact O-N 2.94Å; L389-T391 HydrophobicContact CB-CG2 3.43Å; L389-T391 VanDerWaalsContact CB-CG2 3.43Å; L389-T391 HydrophobicContact CD1-CG2 4.26Å; L389-T391 HydrophobicContact CG-CG2 4.49Å; L389-T391 PolarHBondContact O-N 3.25Å; T391-Q393 VanDerWaalsContact C-N 3.28Å; T391-Q393 PolarHBondContact O-N 3.13Å; T391-Q393 PolarHBondContact OG1-O 3.4Å; T391-Q393 VanDerWaalsContact OG1-O 3.13Å
392G98.8Very high98.7Very high0 Ų012 Ų120%07%0.069CC..SBendtrans80.8-1.1174.400000115.2P147 V148 C390 A425 F429P147-G392 CarbonylContact C-O 3.52Å; P147-G392 VanDerWaalsContact CA-C 3.47Å; P147-G392 WeakPolarHBondContact CA-O 3.41Å; V148-G392 PolarHBondContact N-O 2.89Å; C390-G392 VanDerWaalsContact C-N 3.31Å; C390-G392 PolarHBondContact O-N 3.11Å; G392-A425 WeakPolarHBondContact O-CB 3.5Å; G392-F429 WeakPolarHBondContact O-CB 3.41Å
393Q98.9Very high98.7Very high0 Ų012.6 Ų12.60%07%0.071CC..EExtended strand (participates in β ladder)trans-156.1140.4-178.448.3-178.1-46.100112.5V148 V368 M369 V370 V386 T391 F429V148-Q393 WeakPolarHBondContact O-CA 3.19Å; V368-Q393 VanDerWaalsContact O-CG 3.22Å; V368-Q393 WeakPolarHBondContact O-CG 3.42Å; M369-Q393 HydrophobicContact CB-CG 4.04Å; M369-Q393 HydrophobicContact CG-CG 4.35Å; V370-Q393 PolarHBondContact N-O 3.03Å; V386-Q393 WeakPolarHBondContact CG2-O 3.44Å; T391-Q393 VanDerWaalsContact C-N 3.28Å; T391-Q393 PolarHBondContact O-N 3.13Å; T391-Q393 PolarHBondContact OG1-O 3.4Å; T391-Q393 VanDerWaalsContact OG1-O 3.13Å; Q393-F429 HydrophobicContact CB-CB 4.38Å; Q393-F429 HydrophobicContact CB-CD2 4.03Å; Q393-F429 HydrophobicContact CG-CD2 4.23Å; Q393-F429 PolarHBondContact NE2-O 3.43Å; Q393-F429 VanDerWaalsContact NE2-O 3.11Å
394I98.9Very high98.7Very high0 Ų012.6 Ų12.60%07%0.071CC..EExtended strand (participates in β ladder)trans-137.8135.6178.9-174.4167.2000110.8P147 V148 P149 A150 V370 I382 V386 T396 L411P147-I394 HydrophobicContact CB-CB 4.27Å; P147-I394 HydrophobicContact CB-CG2 3.9Å; P147-I394 HydrophobicContact CG-CB 4.21Å; P147-I394 HydrophobicContact CG-CG2 3.55Å; V148-I394 PolarHBondContact O-N 3.23Å; V148-I394 VanDerWaalsContact O-N 3.09Å; P149-I394 CarbonylContact C-O 3.07Å; A150-I394 PolarHBondContact N-O 2.86Å; V370-I394 HydrophobicContact CB-CG1 4.49Å; V370-I394 WeakPolarHBondContact O-CA 3.35Å; V370-I394 WeakPolarHBondContact O-CG1 3.36Å; I382-I394 HydrophobicContact CD1-CD1 4.49Å; I382-I394 HydrophobicContact CG1-CD1 4.42Å; V386-I394 HydrophobicContact CB-CB 4.41Å; V386-I394 HydrophobicContact CB-CD1 4.33Å; V386-I394 HydrophobicContact CG1-CB 4.27Å; V386-I394 HydrophobicContact CG1-CD1 3.85Å; V386-I394 HydrophobicContact CG2-CB 4.06Å; I394-T396 HydrophobicContact CD1-CG2 4Å; I394-T396 HydrophobicContact CG1-CG2 4.12Å; I394-L411 HydrophobicContact CD1-CD1 4.39Å; I394-L411 HydrophobicContact CG2-CD1 4Å
395K98.8Very high98.7Very high2 Ų214.4 Ų14.41%0.0098%0.081CC..EExtended strand (participates in β ladder)trans-108.8106.5168.2173.9-172.7177.8-1790108.1A150 E168 M170 D246 E294 L342 M369 V370 S371 H372A150-K395 HydrophobicContact CB-CB 4.3Å; E168-K395 WeakPolarHBondContact OE1-CE 3.44Å; E168-K395 IonicContact OE1-NZ 3.56Å; E168-K395 PolarHBondContact OE1-NZ 2.82Å; E168-K395 WeakPolarHBondContact OE2-CE 3.42Å; E168-K395 IonicContact OE2-NZ 3.9Å; E168-K395 PolarHBondContact OE2-NZ 2.95Å; E168-K395 VanDerWaalsContact OE2-NZ 3.08Å; M170-K395 HydrophobicContact CE-CD 4.27Å; M170-K395 HydrophobicContact SD-CB 4.5Å; M170-K395 HydrophobicContact SD-CD 3.74Å; M170-K395 HydrophobicContact SD-CG 3.8Å; D246-K395 IonicContact OD2-NZ 3.51Å; D246-K395 PolarHBondContact OD2-NZ 3.46Å; E294-K395 IonicContact OE1-NZ 3.76Å; E294-K395 PolarHBondContact OE1-NZ 3.04Å; E294-K395 IonicContact OE2-NZ 3.57Å; E294-K395 PolarHBondContact OE2-NZ 3.43Å; L342-K395 HydrophobicContact CD1-CD 4.36Å; M369-K395 HydrophobicContact CG-CB 4.12Å; M369-K395 HydrophobicContact SD-CB 3.6Å; M369-K395 VanDerWaalsContact SD-CB 3.6Å; M369-K395 HydrophobicContact SD-CD 4.35Å; V370-K395 PolarHBondContact O-N 3.48Å; S371-K395 WeakPolarHBondContact CA-O 3.32Å; H372-K395 PolarHBondContact CD2-O 3.47Å; H372-K395 PolarHBondContact N-O 3.26Å
396T98.6Very high98.7Very high0 Ų015.3 Ų15.30%09%0.089CC..  trans-135.533-179.5-1640000113H372 I394 R404 K407 Y408H372-T396 WeakPolarHBondContact ND1-CA 3.09Å; I394-T396 HydrophobicContact CD1-CG2 4Å; I394-T396 HydrophobicContact CG1-CG2 4.12Å; T396-R404 VanDerWaalsContact O-CB 3.24Å; T396-R404 WeakPolarHBondContact O-CB 3.43Å; T396-R404 WeakPolarHBondContact O-CD 3.39Å; T396-K407 HydrophobicContact CG2-CB 3.8Å; T396-Y408 HydrophobicContact CG2-CD1 3.74Å; T396-Y408 HydrophobicContact CG2-CD2 4.19Å; T396-Y408 HydrophobicContact CG2-CE1 3.25Å; T396-Y408 HydrophobicContact CG2-CE2 3.74Å; T396-Y408 HydrophobicContact CG2-CG 4.19Å; T396-Y408 PolarHBondContact N-OH 3Å
397G98.1Very high98.7Very high0 Ų015.4 Ų15.40%09%0.089CC..  trans89.7-173172.800000114.3F151 H372 Y408F151-G397 WeakPolarHBondContact CA-O 3.17Å; H372-G397 VanDerWaalsContact CE1-CA 3.44Å; H372-G397 WeakPolarHBondContact CE1-CA 3.32Å; H372-G397 PolarHBondContact CE1-N 2.94Å; H372-G397 PolarHBondContact ND1-N 2.89Å; G397-Y408 WeakPolarHBondContact O-CE2 3.19Å; G397-Y408 PolarHBondContact O-OH 3.09Å
398A98.6Very high98.7Very high0 Ų015.4 Ų15.40%09%0.089CC..  trans-64.6164176.700000111.9N152 Y190 E211 G212 C400 R404N152-A398 VanDerWaalsContact O-CA 3.27Å; N152-A398 WeakPolarHBondContact O-CA 3.4Å; N152-A398 WeakPolarHBondContact O-CB 3.37Å; N152-A398 PolarHBondContact O-N 2.9Å; Y190-A398 HydrophobicContact CD2-CB 4.49Å; Y190-A398 HydrophobicContact CE2-CB 4.02Å; E211-A398 WeakPolarHBondContact O-CB 3.36Å; E211-A398 PolarHBondContact O-N 3.2Å; G212-A398 WeakPolarHBondContact O-CB 3.48Å; A398-C400 HydrophobicContact CB-CB 3.96Å; A398-C400 PolarHBondContact O-N 3.43Å; A398-R404 WeakPolarHBondContact O-CB 3.42Å
399P98.6Very high98.7Very high15 Ų1518.4 Ų18.410%0.09711%0.105CC..SBendtrans-72.347.6160.434.3-36.4000111.1F151 A187 Y190 L405F151-P399 HydrophobicContact CD1-CB 4.37Å; F151-P399 HydrophobicContact CD1-CG 4.38Å; F151-P399 HydrophobicContact CE1-CB 4.4Å; A187-P399 HydrophobicContact CB-CB 4.33Å; Y190-P399 HydrophobicContact CD1-CG 4.08Å; Y190-P399 HydrophobicContact CD2-CG 4.3Å; Y190-P399 HydrophobicContact CG-CG 3.75Å; P399-L405 HydrophobicContact CB-CD2 4.41Å
400C98.4Very high98.7Very high33 Ų3320 Ų2022%0.22311%0.112CC..  trans-150.5149.8-178.1-173.90000109Y190 A398 R404Y190-C400 HydrophobicContact CE1-CB 3.95Å; Y190-C400 WeakPolarHBondContact OH-CB 3.49Å; A398-C400 HydrophobicContact CB-CB 3.96Å; A398-C400 PolarHBondContact O-N 3.43Å; C400-R404 WeakPolarHBondContact O-CB 3.41Å; C400-R404 VanDerWaalsContact O-CG 3.27Å; C400-R404 WeakPolarHBondContact O-CG 3.36Å
401R98.1Very high98.7Very high82 Ų8219.8 Ų19.831%0.30911%0.111SC..SBendtrans66.8132.8-173.3-47.1174.452.7986.3113.3S15 V208 D210 E403 R404 L405S15-R401 PolarHBondContact O-NH2 2.83Å; V208-R401 HydrophobicContact CG2-CG 4.46Å; D210-R401 PolarHBondContact O-NE 2.87Å; R401-E403 WeakPolarHBondContact CB-OE1 3.32Å; R401-E403 WeakPolarHBondContact CB-OE2 3.21Å; R401-E403 IonicContact CZ-OE1 3.45Å; R401-E403 IonicContact NE-OE1 2.75Å; R401-E403 PolarHBondContact NE-OE1 2.99Å; R401-E403 IonicContact NE-OE2 2.98Å; R401-E403 IonicContact NH2-OE1 3.55Å; R401-E403 PolarHBondContact NH2-OE1 2.91Å; R401-E403 PolarHBondContact O-N 3.2Å; R401-R404 HydrophobicContact CB-CG 4.28Å; R401-R404 WeakPolarHBondContact O-CB 3.48Å; R401-R404 PolarHBondContact O-N 2.76Å; R401-R404 VanDerWaalsContact O-N 3.11Å; R401-L405 PolarHBondContact O-N 3.29Å
402S98.8Very high98.7Very high97 Ų9722.2 Ų22.268%0.67812%0.123SC*.Hα-helixtrans-73.1-24.7-164.4-64.80000114.1R404 L405 A406S402-R404 PolarHBondContact O-N 3.15Å; S402-L405 PolarHBondContact O-N 3.49Å; S402-A406 WeakPolarHBondContact O-CA 3.38Å; S402-A406 WeakPolarHBondContact O-CB 3.38Å; S402-A406 PolarHBondContact O-N 3.5Å
403E98.6Very high98.7Very high20 Ų2028.7 Ų28.79%0.09315%0.148CC..Hα-helixtrans-63.8-22.8172.477.3-79-172.400112.3S15 E376 T377 R401 K407S15-E403 VanDerWaalsContact CB-CG 3.48Å; E376-E403 HydrophobicContact CB-CB 3.9Å; E376-E403 HydrophobicContact CB-CG 3.67Å; T377-E403 WeakPolarHBondContact O-CB 3.28Å; R401-E403 WeakPolarHBondContact CB-OE1 3.32Å; R401-E403 WeakPolarHBondContact CB-OE2 3.21Å; R401-E403 IonicContact CZ-OE1 3.45Å; R401-E403 IonicContact NE-OE1 2.75Å; R401-E403 PolarHBondContact NE-OE1 2.99Å; R401-E403 IonicContact NE-OE2 2.98Å; R401-E403 IonicContact NH2-OE1 3.55Å; R401-E403 PolarHBondContact NH2-OE1 2.91Å; R401-E403 PolarHBondContact O-N 3.2Å; E403-K407 VanDerWaalsContact O-CD 3.25Å; E403-K407 WeakPolarHBondContact O-CD 3.42Å; E403-K407 WeakPolarHBondContact O-CE 3.19Å; E403-K407 PolarHBondContact O-NZ 2.8Å
404R98.7Very high98.7Very high0 Ų028.8 Ų28.80%015%0.148CC..Hα-helixtrans-87.2-55.4174-43.6-52.6166.1-178.85.3109.8D210 H372 R373 S374 E376 T396 A398 C400 R401 S402 A406 K407 Y408D210-R404 PolarHBondContact O-NH2 2.79Å; H372-R404 PolarHBondContact ND1-NH1 3.45Å; H372-R404 VanDerWaalsContact ND1-NH1 3.13Å; R373-R404 PolarHBondContact O-NH1 2.92Å; S374-R404 PolarHBondContact O-NH2 3.12Å; E376-R404 VanDerWaalsContact CB-NH1 3.34Å; T396-R404 VanDerWaalsContact O-CB 3.24Å; T396-R404 WeakPolarHBondContact O-CB 3.43Å; T396-R404 WeakPolarHBondContact O-CD 3.39Å; A398-R404 WeakPolarHBondContact O-CB 3.42Å; C400-R404 WeakPolarHBondContact O-CB 3.41Å; C400-R404 VanDerWaalsContact O-CG 3.27Å; C400-R404 WeakPolarHBondContact O-CG 3.36Å; R401-R404 HydrophobicContact CB-CG 4.28Å; R401-R404 WeakPolarHBondContact O-CB 3.48Å; R401-R404 PolarHBondContact O-N 2.76Å; R401-R404 VanDerWaalsContact O-N 3.11Å; S402-R404 PolarHBondContact O-N 3.15Å; R404-A406 PolarHBondContact O-N 3.41Å; R404-A406 VanDerWaalsContact O-N 3.14Å; R404-K407 PolarHBondContact O-N 3.08Å; R404-Y408 HydrophobicContact CB-CE2 4.49Å; R404-Y408 WeakPolarHBondContact O-CD2 3.23Å; R404-Y408 PolarHBondContact O-N 2.69Å
405L98.9Very high98.7Very high45 Ų4529.9 Ų29.924%0.23615%0.154CC..Hα-helixtrans-60.7-26-179.8-67.5171.1000112.7P399 R401 S402 K407 Y408 N409P399-L405 HydrophobicContact CB-CD2 4.41Å; R401-L405 PolarHBondContact O-N 3.29Å; S402-L405 PolarHBondContact O-N 3.49Å; L405-K407 VanDerWaalsContact C-N 3.29Å; L405-K407 PolarHBondContact O-N 3.24Å; L405-Y408 HydrophobicContact CD2-CD2 4.48Å; L405-Y408 PolarHBondContact O-N 3.2Å; L405-N409 WeakPolarHBondContact O-CB 3.47Å; L405-N409 PolarHBondContact O-N 3.08Å; L405-N409 PolarHBondContact O-ND2 2.99Å; L405-N409 VanDerWaalsContact O-ND2 3.11Å
406A98.9Very high98.7Very high20 Ų2037.7 Ų37.717%0.16519%0.19CC..Hα-helixtrans-57-43.6174.700000111.4T380 S402 R404 Q410T380-A406 HydrophobicContact CG2-CB 3.77Å; T380-A406 VanDerWaalsContact CG2-O 3.26Å; T380-A406 WeakPolarHBondContact CG2-O 3.46Å; S402-A406 WeakPolarHBondContact O-CA 3.38Å; S402-A406 WeakPolarHBondContact O-CB 3.38Å; S402-A406 PolarHBondContact O-N 3.5Å; R404-A406 PolarHBondContact O-N 3.41Å; R404-A406 VanDerWaalsContact O-N 3.14Å; A406-Q410 WeakPolarHBondContact O-CB 3.18Å; A406-Q410 PolarHBondContact O-N 3.06Å
407K98.9Very high98.7Very high1 Ų143.3 Ų43.30%0.00422%0.216CC..Hα-helixtrans-72.4-45.6179.4-73.865.1160.2175.40110.9E376 T377 D379 I382 A383 T396 E403 R404 L405 N409 Q410 L411E376-K407 WeakPolarHBondContact OE1-CE 3.28Å; E376-K407 IonicContact OE1-NZ 3.43Å; E376-K407 WeakPolarHBondContact OE2-CE 3.3Å; E376-K407 IonicContact OE2-NZ 2.84Å; E376-K407 PolarHBondContact OE2-NZ 3.45Å; T377-K407 PolarHBondContact O-NZ 2.92Å; D379-K407 WeakPolarHBondContact O-CD 3.49Å; D379-K407 WeakPolarHBondContact O-CE 3.3Å; D379-K407 PolarHBondContact O-NZ 3.41Å; I382-K407 HydrophobicContact CD1-CG 4.02Å; I382-K407 HydrophobicContact CG1-CG 3.58Å; A383-K407 HydrophobicContact CB-CB 4.21Å; A383-K407 WeakPolarHBondContact CB-O 3.45Å; T396-K407 HydrophobicContact CG2-CB 3.8Å; E403-K407 VanDerWaalsContact O-CD 3.25Å; E403-K407 WeakPolarHBondContact O-CD 3.42Å; E403-K407 WeakPolarHBondContact O-CE 3.19Å; E403-K407 PolarHBondContact O-NZ 2.8Å; R404-K407 PolarHBondContact O-N 3.08Å; L405-K407 VanDerWaalsContact C-N 3.29Å; L405-K407 PolarHBondContact O-N 3.24Å; K407-N409 VanDerWaalsContact C-N 3.34Å; K407-N409 PolarHBondContact O-N 2.97Å; K407-Q410 WeakPolarHBondContact O-CB 3.47Å; K407-Q410 PolarHBondContact O-N 2.91Å; K407-Q410 VanDerWaalsContact O-N 3.13Å; K407-L411 WeakPolarHBondContact O-CG 3.29Å; K407-L411 PolarHBondContact O-N 2.92Å
408Y98.9Very high98.8Very high0 Ų044.5 Ų44.50%022%0.223CC..Hα-helixtrans-61.4-41.7176.3-67.9-48.4000112.6P149 F151 F179 M183 T396 G397 R404 L405 Q410 L411 L412P149-Y408 HydrophobicContact CB-CD1 4.26Å; P149-Y408 HydrophobicContact CB-CE1 3.61Å; F151-Y408 HydrophobicContact CD1-CE1 4.08Å; F151-Y408 AromaticContact CD1-CE2 3.75Å; F151-Y408 HydrophobicContact CD1-CE2 3.75Å; F151-Y408 AromaticContact CD1-CZ 3.47Å; F151-Y408 VanDerWaalsContact CD1-CZ 3.47Å; F151-Y408 WeakPolarHBondContact CD1-OH 3.31Å; F151-Y408 HydrophobicContact CE1-CD1 4.03Å; F151-Y408 HydrophobicContact CE1-CD2 4.11Å; F151-Y408 AromaticContact CE1-CE1 3.61Å; F151-Y408 HydrophobicContact CE1-CE1 3.61Å; F151-Y408 AromaticContact CE1-CE2 3.7Å; F151-Y408 HydrophobicContact CE1-CE2 3.7Å; F151-Y408 HydrophobicContact CE1-CG 4.27Å; F151-Y408 AromaticContact CE1-CZ 3.43Å; F151-Y408 VanDerWaalsContact CE1-CZ 3.43Å; F151-Y408 HydrophobicContact CZ-CE1 4.43Å; F179-Y408 WeakPolarHBondContact CE1-O 3.35Å; F179-Y408 HydrophobicContact CZ-CD1 4.08Å; M183-Y408 HydrophobicContact CE-CD1 4.48Å; M183-Y408 HydrophobicContact CE-CD2 4.24Å; M183-Y408 HydrophobicContact CE-CG 3.88Å; M183-Y408 VanDerWaalsContact SD-CB 3.59Å; M183-Y408 HydrophobicContact SD-CD1 3.67Å; M183-Y408 HydrophobicContact SD-CD2 4.44Å; M183-Y408 HydrophobicContact SD-CE1 4.46Å; M183-Y408 HydrophobicContact SD-CG 3.65Å; T396-Y408 HydrophobicContact CG2-CD1 3.74Å; T396-Y408 HydrophobicContact CG2-CD2 4.19Å; T396-Y408 HydrophobicContact CG2-CE1 3.25Å; T396-Y408 HydrophobicContact CG2-CE2 3.74Å; T396-Y408 HydrophobicContact CG2-CG 4.19Å; T396-Y408 PolarHBondContact N-OH 3Å; G397-Y408 WeakPolarHBondContact O-CE2 3.19Å; G397-Y408 PolarHBondContact O-OH 3.09Å; R404-Y408 HydrophobicContact CB-CE2 4.49Å; R404-Y408 WeakPolarHBondContact O-CD2 3.23Å; R404-Y408 PolarHBondContact O-N 2.69Å; L405-Y408 HydrophobicContact CD2-CD2 4.48Å; L405-Y408 PolarHBondContact O-N 3.2Å; Y408-Q410 VanDerWaalsContact C-N 3.31Å; Y408-Q410 PolarHBondContact O-N 3.21Å; Y408-L411 HydrophobicContact CD1-CD1 4.47Å; Y408-L411 WeakPolarHBondContact O-CB 3.23Å; Y408-L411 PolarHBondContact O-N 3.4Å; Y408-L412 PolarHBondContact O-N 3.32Å
409N98.9Very high98.8Very high64 Ų6446.4 Ų46.434%0.34224%0.242SC..Hα-helixtrans-67.3-33.4174.8-71-27.1000111.8L405 K407 L412 R413L405-N409 WeakPolarHBondContact O-CB 3.47Å; L405-N409 PolarHBondContact O-N 3.08Å; L405-N409 PolarHBondContact O-ND2 2.99Å; L405-N409 VanDerWaalsContact O-ND2 3.11Å; K407-N409 VanDerWaalsContact C-N 3.34Å; K407-N409 PolarHBondContact O-N 2.97Å; N409-L412 PolarHBondContact O-N 3.49Å; N409-R413 WeakPolarHBondContact O-CG 3.38Å; N409-R413 PolarHBondContact O-N 3.09Å; N409-R413 VanDerWaalsContact O-N 3.13Å
410Q98.9Very high98.7Very high36 Ų3653.3 Ų53.317%0.16828%0.279CS..Hα-helixtrans-65-41.1172.4-178.861.95.400111.5T380 A383 D384 A406 K407 Y408 L412 R413 I414T380-Q410 HydrophobicContact CG2-CB 4.04Å; A383-Q410 HydrophobicContact CB-CB 3.74Å; A383-Q410 HydrophobicContact CB-CG 3.67Å; D384-Q410 WeakPolarHBondContact OD2-CG 2.92Å; D384-Q410 PolarHBondContact OD2-NE2 2.67Å; A406-Q410 WeakPolarHBondContact O-CB 3.18Å; A406-Q410 PolarHBondContact O-N 3.06Å; K407-Q410 WeakPolarHBondContact O-CB 3.47Å; K407-Q410 PolarHBondContact O-N 2.91Å; K407-Q410 VanDerWaalsContact O-N 3.13Å; Y408-Q410 VanDerWaalsContact C-N 3.31Å; Y408-Q410 PolarHBondContact O-N 3.21Å; Q410-L412 VanDerWaalsContact C-N 3.34Å; Q410-L412 PolarHBondContact O-N 3.29Å; Q410-R413 WeakPolarHBondContact O-CB 3.42Å; Q410-R413 PolarHBondContact O-N 2.9Å; Q410-R413 VanDerWaalsContact O-N 3.12Å; Q410-I414 HydrophobicContact CG-CD1 4.01Å; Q410-I414 HydrophobicContact CG-CG1 4.48Å; Q410-I414 WeakPolarHBondContact O-CG1 3.31Å; Q410-I414 PolarHBondContact O-N 2.65Å
411L98.9Very high98.7Very high0 Ų059.6 Ų59.60%030%0.302CS..Hα-helixtrans-63.1-36.8174.2-69.7168.4000112.7L146 P147 F179 A383 V386 V387 I394 K407 Y408 R413 I414 E415L146-L411 HydrophobicContact CD1-CB 4.43Å; L146-L411 HydrophobicContact CD1-CD2 4.13Å; P147-L411 HydrophobicContact CG-CD1 3.96Å; P147-L411 HydrophobicContact CG-CD2 4.06Å; F179-L411 HydrophobicContact CD1-CB 3.79Å; F179-L411 HydrophobicContact CD2-CB 4.41Å; F179-L411 HydrophobicContact CE1-CB 3.24Å; F179-L411 HydrophobicContact CE1-CD1 4.26Å; F179-L411 HydrophobicContact CE1-CG 4.37Å; F179-L411 HydrophobicContact CE2-CB 3.94Å; F179-L411 HydrophobicContact CE2-CD1 3.58Å; F179-L411 HydrophobicContact CE2-CG 4.33Å; F179-L411 HydrophobicContact CG-CB 4.35Å; F179-L411 HydrophobicContact CZ-CB 3.33Å; F179-L411 HydrophobicContact CZ-CD1 3.42Å; F179-L411 VanDerWaalsContact CZ-CD1 3.42Å; F179-L411 HydrophobicContact CZ-CG 4Å; A383-L411 HydrophobicContact CB-CD2 4.12Å; A383-L411 HydrophobicContact CB-CG 3.89Å; A383-L411 WeakPolarHBondContact O-CD2 3.47Å; V386-L411 HydrophobicContact CG1-CD2 3.94Å; V387-L411 HydrophobicContact CG2-CD2 3.56Å; I394-L411 HydrophobicContact CD1-CD1 4.39Å; I394-L411 HydrophobicContact CG2-CD1 4Å; K407-L411 WeakPolarHBondContact O-CG 3.29Å; K407-L411 PolarHBondContact O-N 2.92Å; Y408-L411 HydrophobicContact CD1-CD1 4.47Å; Y408-L411 WeakPolarHBondContact O-CB 3.23Å; Y408-L411 PolarHBondContact O-N 3.4Å; L411-R413 VanDerWaalsContact C-N 3.32Å; L411-R413 PolarHBondContact O-N 2.81Å; L411-I414 PolarHBondContact O-N 3.44Å; L411-E415 WeakPolarHBondContact O-CB 3.2Å; L411-E415 PolarHBondContact O-N 3.23Å
412L98.9Very high98.6Very high51 Ų5156.7 Ų56.727%0.26730%0.296SS..Hα-helixtrans-60.6-41.3171.3-69.8171.2000111.9F179 K180 M183 Y408 N409 Q410 E416F179-L412 HydrophobicContact CD1-CD2 3.9Å; F179-L412 HydrophobicContact CD1-CG 4.22Å; F179-L412 HydrophobicContact CE1-CD2 4.13Å; F179-L412 HydrophobicContact CE1-CG 4.04Å; K180-L412 HydrophobicContact CB-CD2 3.83Å; K180-L412 HydrophobicContact CG-CD2 4.14Å; M183-L412 HydrophobicContact CB-CD2 4.4Å; M183-L412 HydrophobicContact CG-CD2 4.12Å; M183-L412 HydrophobicContact CG-CG 4.35Å; Y408-L412 PolarHBondContact O-N 3.32Å; N409-L412 PolarHBondContact O-N 3.49Å; Q410-L412 VanDerWaalsContact C-N 3.34Å; Q410-L412 PolarHBondContact O-N 3.29Å; L412-E416 PolarHBondContact O-N 3.06Å
413R98.9Very high98.6Very high136 Ų13659.1 Ų59.151%0.51329%0.29SS..Hα-helixtrans-68.3-41177-66.1178.9-156.9109.93.7112.1N409 Q410 L411 E416 E417N409-R413 WeakPolarHBondContact O-CG 3.38Å; N409-R413 PolarHBondContact O-N 3.09Å; N409-R413 VanDerWaalsContact O-N 3.13Å; Q410-R413 WeakPolarHBondContact O-CB 3.42Å; Q410-R413 PolarHBondContact O-N 2.9Å; Q410-R413 VanDerWaalsContact O-N 3.12Å; L411-R413 VanDerWaalsContact C-N 3.32Å; L411-R413 PolarHBondContact O-N 2.81Å; R413-E416 PolarHBondContact O-N 3.31Å; R413-E417 WeakPolarHBondContact O-CB 3.4Å; R413-E417 PolarHBondContact O-N 2.86Å
414I98.9Very high98.6Very high2 Ų259.8 Ų59.81%0.0129%0.293CS..Hα-helixtrans-63.7-43.1176.6-67167.3000110.4Y132 V387 Q410 L411 E416 E417 L418Y132-I414 HydrophobicContact CD1-CB 4.39Å; Y132-I414 HydrophobicContact CD1-CD1 3.98Å; Y132-I414 HydrophobicContact CD1-CG1 3.75Å; Y132-I414 HydrophobicContact CD1-CG2 3.82Å; Y132-I414 HydrophobicContact CE1-CB 4.38Å; Y132-I414 HydrophobicContact CE1-CG1 4.01Å; Y132-I414 HydrophobicContact CE1-CG2 3.83Å; Y132-I414 HydrophobicContact CG-CG2 4.2Å; V387-I414 HydrophobicContact CG1-CG2 4Å; V387-I414 HydrophobicContact CG2-CD1 4.31Å; V387-I414 HydrophobicContact CG2-CG2 4.14Å; Q410-I414 HydrophobicContact CG-CD1 4.01Å; Q410-I414 HydrophobicContact CG-CG1 4.48Å; Q410-I414 WeakPolarHBondContact O-CG1 3.31Å; Q410-I414 PolarHBondContact O-N 2.65Å; L411-I414 PolarHBondContact O-N 3.44Å; I414-E416 VanDerWaalsContact C-N 3.35Å; I414-E416 PolarHBondContact O-N 3.03Å; I414-E417 PolarHBondContact O-N 3.11Å; I414-L418 HydrophobicContact CG2-CD1 3.79Å; I414-L418 HydrophobicContact CG2-CG 4.39Å; I414-L418 WeakPolarHBondContact O-CB 3.27Å; I414-L418 VanDerWaalsContact O-CG 3.3Å; I414-L418 WeakPolarHBondContact O-CG 3.49Å; I414-L418 PolarHBondContact O-N 2.87Å
415E98.9Very high98.6Very high24 Ų2460 Ų6011%0.11230%0.295CS..Hα-helixtrans-59.4-45.1174.3178.5170.4-110.100111.8L146 N178 F179 K180 L411 L418 G419 A422L146-E415 HydrophobicContact CD1-CB 4.16Å; L146-E415 HydrophobicContact CG-CB 4.17Å; N178-E415 WeakPolarHBondContact CB-OE1 3.22Å; F179-E415 WeakPolarHBondContact CA-OE1 3.44Å; F179-E415 VanDerWaalsContact CB-OE1 3.25Å; F179-E415 WeakPolarHBondContact CB-OE1 3.26Å; F179-E415 PolarHBondContact N-OE1 3.12Å; K180-E415 VanDerWaalsContact CB-OE2 3.22Å; K180-E415 WeakPolarHBondContact CB-OE2 3.41Å; K180-E415 PolarHBondContact N-OE2 2.77Å; L411-E415 WeakPolarHBondContact O-CB 3.2Å; L411-E415 PolarHBondContact O-N 3.23Å; E415-L418 PolarHBondContact O-N 3.34Å; E415-G419 PolarHBondContact O-N 2.62Å; E415-G419 VanDerWaalsContact O-N 3.15Å; E415-A422 HydrophobicContact CG-CB 4.14Å
416E98.8Very high98.6Very high166 Ų16658.2 Ų58.278%0.77629%0.287SS*.Hα-helixtrans-61.8-44.3176.5-175177.59500112.2L412 R413 I414 L418 G419L412-E416 PolarHBondContact O-N 3.06Å; R413-E416 PolarHBondContact O-N 3.31Å; I414-E416 VanDerWaalsContact C-N 3.35Å; I414-E416 PolarHBondContact O-N 3.03Å; E416-L418 VanDerWaalsContact C-N 3.35Å; E416-L418 PolarHBondContact O-N 2.85Å; E416-G419 PolarHBondContact O-N 3.48Å
417E98.8Very high98.6Very high117 Ų11765.1 Ų65.155%0.54731%0.313SS..Hα-helixtrans-64.5-37.7178.8-173.6-178.9-16000112.5P130 Y132 R413 I414 G419P130-E417 WeakPolarHBondContact CG-OE1 3.31Å; Y132-E417 WeakPolarHBondContact CE1-OE2 3.46Å; Y132-E417 VanDerWaalsContact OH-CD 3.27Å; Y132-E417 PolarHBondContact OH-OE2 2.99Å; R413-E417 WeakPolarHBondContact O-CB 3.4Å; R413-E417 PolarHBondContact O-N 2.86Å; I414-E417 PolarHBondContact O-N 3.11Å; E417-G419 VanDerWaalsContact C-N 3.31Å
418L98.6Very high98.6Very high25 Ų2570.3 Ų70.313%0.13134%0.341CS..Hα-helixtrans-71.3-26.1177.3-73168.6000112.7Y132 V144 L146 I414 E415 E416 D420 K421 A422Y132-L418 HydrophobicContact CE2-CD2 4.01Å; Y132-L418 HydrophobicContact CE2-CG 4.46Å; V144-L418 HydrophobicContact CG2-CD1 3.8Å; V144-L418 HydrophobicContact CG2-CD2 3.77Å; V144-L418 HydrophobicContact CG2-CG 4.48Å; L146-L418 HydrophobicContact CD2-CD1 3.63Å; I414-L418 HydrophobicContact CG2-CD1 3.79Å; I414-L418 HydrophobicContact CG2-CG 4.39Å; I414-L418 WeakPolarHBondContact O-CB 3.27Å; I414-L418 VanDerWaalsContact O-CG 3.3Å; I414-L418 WeakPolarHBondContact O-CG 3.49Å; I414-L418 PolarHBondContact O-N 2.87Å; E415-L418 PolarHBondContact O-N 3.34Å; E416-L418 VanDerWaalsContact C-N 3.35Å; E416-L418 PolarHBondContact O-N 2.85Å; L418-D420 PolarHBondContact O-N 3.42Å; L418-K421 WeakPolarHBondContact O-CB 3.39Å; L418-K421 PolarHBondContact O-N 2.92Å; L418-A422 HydrophobicContact CB-CB 3.92Å
419G98.4Very high98.6Very high40 Ų4070.9 Ų70.941%0.41234%0.343SS..G310 helixtrans52.2-128.117900000112.2E415 E416 E417 K421 A422E415-G419 PolarHBondContact O-N 2.62Å; E415-G419 VanDerWaalsContact O-N 3.15Å; E416-G419 PolarHBondContact O-N 3.48Å; E417-G419 VanDerWaalsContact C-N 3.31Å; G419-K421 PolarHBondContact O-N 2.6Å; G419-A422 VanDerWaalsContact O-CB 3.22Å; G419-A422 WeakPolarHBondContact O-CB 3.38Å; G419-A422 PolarHBondContact O-N 3Å
420D97.6Very high98.5Very high161 Ų16171.7 Ų71.786%0.86134%0.342SS*.G310 helixtrans-63.4-14.2-179.5-62.1-27.6000114.3L418 R423L418-D420 PolarHBondContact O-N 3.42Å; D420-R423 PolarHBondContact O-NH1 2.86Å
421K97.3Very high98.4Very high165 Ų16578.2 Ų78.272%0.71737%0.365SS*.G310 helixtrans-84.5-13.2174.5-58.2-179.8-178175.90112.5L418 G419 R423L418-K421 WeakPolarHBondContact O-CB 3.39Å; L418-K421 PolarHBondContact O-N 2.92Å; G419-K421 PolarHBondContact O-N 2.6Å; K421-R423 PolarHBondContact O-N 3.19Å
422A97.8Very high98.1Very high21 Ų2179.6 Ų79.617%0.17437%0.373CS..  trans-60.3131.6177.500000110.2L146 E415 L418 G419L146-A422 HydrophobicContact CD2-CB 4.46Å; E415-A422 HydrophobicContact CG-CB 4.14Å; L418-A422 HydrophobicContact CB-CB 3.92Å; G419-A422 VanDerWaalsContact O-CB 3.22Å; G419-A422 WeakPolarHBondContact O-CB 3.38Å; G419-A422 PolarHBondContact O-N 3Å
423R98.4Very high97.5Very high148 Ų14884.6 Ų84.656%0.55840%0.399SS*.  trans-127129.3173.8-65.8-64.8177.5-87.7-2107.3I145 L146 D420 K421I145-R423 HydrophobicContact CD1-CB 4.39Å; I145-R423 HydrophobicContact CG1-CB 3.86Å; I145-R423 VanDerWaalsContact CG1-O 3.22Å; I145-R423 WeakPolarHBondContact CG1-O 3.46Å; L146-R423 WeakPolarHBondContact CB-O 3.36Å; L146-R423 PolarHBondContact N-O 2.65Å; D420-R423 PolarHBondContact O-NH1 2.86Å; K421-R423 PolarHBondContact O-N 3.19Å
424F98.8Very high97.4Very high34 Ų3482 Ų8215%0.14939%0.393CS..BIsolated β-bridgetrans-102.6132178.3175.4-114.3000109.3L146 P147 V148 A176 F179 A182 G426L146-F424 HydrophobicContact CB-CD2 4.29Å; P147-F424 WeakPolarHBondContact O-CE2 3.43Å; V148-F424 HydrophobicContact CB-CZ 4.42Å; V148-F424 HydrophobicContact CG2-CE1 4.33Å; V148-F424 HydrophobicContact CG2-CE2 4.13Å; V148-F424 HydrophobicContact CG2-CZ 3.74Å; A176-F424 HydrophobicContact CB-CE1 3.92Å; A176-F424 HydrophobicContact CB-CZ 4.24Å; A176-F424 WeakPolarHBondContact O-CE1 3.32Å; F179-F424 HydrophobicContact CB-CD2 4.18Å; F179-F424 HydrophobicContact CB-CE2 4.47Å; F179-F424 HydrophobicContact CD2-CE2 4.35Å; A182-F424 HydrophobicContact CB-CE2 4.03Å; A182-F424 HydrophobicContact CB-CZ 3.74Å; F424-G426 VanDerWaalsContact C-N 3.3Å; F424-G426 VanDerWaalsContact CE1-CA 3.5Å; F424-G426 PolarHBondContact O-N 3.24Å
425A98.8Very high97.3Very high5 Ų586.2 Ų86.24%0.04141%0.413CS..  trans-63.1-35.1-174.400000113.2I145 L146 V148 G392 K427 N428 F429 P432I145-A425 HydrophobicContact CD1-CB 4.28Å; L146-A425 PolarHBondContact O-N 3.04Å; V148-A425 HydrophobicContact CG2-CB 4.45Å; G392-A425 WeakPolarHBondContact O-CB 3.5Å; A425-K427 PolarHBondContact O-N 3.33Å; A425-N428 WeakPolarHBondContact O-CA 3.24Å; A425-N428 WeakPolarHBondContact O-CB 3.28Å; A425-N428 PolarHBondContact O-N 3.13Å; A425-F429 HydrophobicContact CB-CB 4.48Å; A425-P432 HydrophobicContact CB-CB 4.04Å
426G98.7Very high97.2Very high7 Ų789.7 Ų89.77%0.07243%0.43CS..G310 helixtrans49.3-128.8177.100000112.9V148 V174 F424 N428 F429V148-G426 VanDerWaalsContact CG2-O 3.27Å; V148-G426 WeakPolarHBondContact CG2-O 3.3Å; V174-G426 CarbonylContact O-C 3.52Å; V174-G426 VanDerWaalsContact O-C 3.3Å; V174-G426 WeakPolarHBondContact O-CA 3.37Å; F424-G426 VanDerWaalsContact C-N 3.3Å; F424-G426 VanDerWaalsContact CE1-CA 3.5Å; F424-G426 PolarHBondContact O-N 3.24Å; G426-N428 PolarHBondContact O-N 3.25Å; G426-N428 VanDerWaalsContact O-N 3.12Å; G426-F429 WeakPolarHBondContact O-CB 3.19Å; G426-F429 PolarHBondContact O-N 2.72Å
427K98.3Very high97.1Very high164 Ų16485.2 Ų85.271%0.71341%0.41SS*.G310 helixtrans-62.9-17.3178.8-64-174.2178.9-178.10114.1V174 A425 F429V174-K427 PolarHBondContact O-N 3.05Å; A425-K427 PolarHBondContact O-N 3.33Å; K427-F429 VanDerWaalsContact C-N 3.35Å
428N98.3Very high97Very high111 Ų11183.2 Ų83.259%0.59440%0.401SS*.G310 helixtrans-92.514.1179.3-60.6-30.8000113.2A425 G426 R430 R431 P432A425-N428 WeakPolarHBondContact O-CA 3.24Å; A425-N428 WeakPolarHBondContact O-CB 3.28Å; A425-N428 PolarHBondContact O-N 3.13Å; G426-N428 PolarHBondContact O-N 3.25Å; G426-N428 VanDerWaalsContact O-N 3.12Å; N428-R430 PolarHBondContact O-N 3.45Å; N428-R431 CarbonylContact O-C 3.51Å; N428-R431 PolarHBondContact O-N 3.31Å; N428-P432 WeakPolarHBondContact O-CA 3.27Å; N428-P432 VanDerWaalsContact O-N 3.15Å
429F98.7Very high96.9Very high12 Ų1287.1 Ų87.15%0.05342%0.419CS..THydrogen-bonded Turntrans-49.5-28.4-175.477.4-84.9000115.8V148 L172 V174 V291 G392 Q393 A425 G426 K427V148-F429 HydrophobicContact CB-CB 3.99Å; V148-F429 HydrophobicContact CG2-CB 3.66Å; L172-F429 HydrophobicContact CD2-CE2 4.38Å; V174-F429 HydrophobicContact CG1-CD1 3.91Å; V174-F429 HydrophobicContact CG1-CE1 4.18Å; V291-F429 HydrophobicContact CG2-CE1 4.5Å; V291-F429 HydrophobicContact CG2-CZ 4.12Å; G392-F429 WeakPolarHBondContact O-CB 3.41Å; Q393-F429 HydrophobicContact CB-CB 4.38Å; Q393-F429 HydrophobicContact CB-CD2 4.03Å; Q393-F429 HydrophobicContact CG-CD2 4.23Å; Q393-F429 PolarHBondContact NE2-O 3.43Å; Q393-F429 VanDerWaalsContact NE2-O 3.11Å; A425-F429 HydrophobicContact CB-CB 4.48Å; G426-F429 WeakPolarHBondContact O-CB 3.19Å; G426-F429 PolarHBondContact O-N 2.72Å; K427-F429 VanDerWaalsContact C-N 3.35Å
430R98.6Very high96.8Very high81 Ų8190.4 Ų90.431%0.30642%0.419SS..THydrogen-bonded Turntrans-71.5-34.1178-59.5178.165.71795.5113S313 I314 N339 G367 N428S313-R430 PolarHBondContact O-NH1 2.94Å; I314-R430 PolarHBondContact O-NH2 2.9Å; I314-R430 VanDerWaalsContact O-NH2 3.08Å; N339-R430 PolarHBondContact ND2-NH2 2.75Å; N339-R430 PolarHBondContact OD1-NH2 3.05Å; G367-R430 WeakPolarHBondContact CA-O 3.02Å; N428-R430 PolarHBondContact O-N 3.45Å
431R95.8Very high96.7Very high173 Ų17385 Ų8565%0.65339%0.386SS*.SBendtrans-151.178.7-175.3-65.6-171.9-174.7168.73.8108.9G365 N428G365-R431 PolarHBondContact O-NE 3.35Å; G365-R431 PolarHBondContact O-NH2 3.16Å; N428-R431 CarbonylContact O-C 3.51Å; N428-R431 PolarHBondContact O-N 3.31Å
432P93.7Very high96.7Very high28 Ų2878.3 Ų78.318%0.18236%0.358CS..  trans-75.7-21.8-171.727.5-35.8000114.8I145 C390 A425 N428I145-P432 HydrophobicContact CD1-CB 3.42Å; I145-P432 VanDerWaalsContact CD1-CB 3.42Å; I145-P432 HydrophobicContact CG1-CB 4.48Å; I145-P432 HydrophobicContact CG2-CB 3.89Å; I145-P432 HydrophobicContact CG2-CG 4.05Å; C390-P432 WeakPolarHBondContact O-CG 3.18Å; A425-P432 HydrophobicContact CB-CB 4.04Å; N428-P432 WeakPolarHBondContact O-CA 3.27Å; N428-P432 VanDerWaalsContact O-N 3.15Å
433I84.6Confident96.6Very high156 Ų15683.5 Ų83.580%0.838%0.375SS*.  trans-130.60-176.8-54.9-174.1000109.1C390C390-I433 HydrophobicContact CB-CD1 3.46Å; C390-I433 VanDerWaalsContact CB-CD1 3.46Å; C390-I433 HydrophobicContact CB-CG1 4.34Å

Retrieved 433 of 433 residues in 858.6 ms (Link to these results)