A0A087Y8Y4_POEFO Loading...

FAM20B glycosaminoglycan xylosylkinase

AlphaFold DB , UniProt , Accession A0A087Y8Y4, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 411 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M55.4Low70.4Confident141 Ų141128.6 Ų128.670%0.69563%0.632SS**  0127.80-80.1164.668.400109.7Q5 R6 V9M1-Q5 HydrophobicContact CB-CB 4.01Å; M1-Q5 HydrophobicContact CE-CB 3.84Å; M1-Q5 HydrophobicContact CG-CB 4.28Å; M1-R6 HydrophobicContact CB-CG 4.33Å; M1-V9 HydrophobicContact CE-CG2 3.8Å
2K70.4Confident70.9Confident177 Ų177122 Ų12277%0.7761%0.613SS**  trans-63.2151.4176.4-69.5176.7175.6176.70109.7K4 Q5 R6K2-K4 PolarHBondContact O-N 3.01Å; K2-Q5 WeakPolarHBondContact O-CA 3.38Å; K2-Q5 WeakPolarHBondContact O-CB 3.29Å; K2-Q5 PolarHBondContact O-N 3.49Å; K2-R6 PolarHBondContact O-N 3.4Å
3L69.2Low71.4Confident151 Ų151118 Ų11879%0.79160%0.598SS**Hα-helixtrans-49.1-37.3-175.5-159.876.8000113.1Q5 R6 M7L3-Q5 PolarHBondContact O-N 3.46Å; L3-R6 PolarHBondContact O-N 3.33Å; L3-M7 PolarHBondContact O-N 3.19Å; L3-M7 VanDerWaalsContact O-N 3.11Å
4K67.6Low71.7Confident180 Ų180117.3 Ų117.378%0.78360%0.596SS**Hα-helixtrans-59.9-40.4174.1-70.4-172.8175-175.30113.7K2 M7 V8K2-K4 PolarHBondContact O-N 3.01Å; K4-M7 PolarHBondContact O-N 3.13Å; K4-V8 VanDerWaalsContact O-CG2 3.32Å; K4-V8 WeakPolarHBondContact O-CG2 3.34Å; K4-V8 PolarHBondContact O-N 3.08Å; K4-V8 VanDerWaalsContact O-N 3.12Å
5Q68.1Low72.1Confident111 Ų111117.3 Ų117.352%0.51960%0.597SS.*Hα-helixtrans-68.4-34.6177.3-100.5174.1-24.800112.2M1 K2 L3 V9M1-Q5 HydrophobicContact CB-CB 4.01Å; M1-Q5 HydrophobicContact CE-CB 3.84Å; M1-Q5 HydrophobicContact CG-CB 4.28Å; K2-Q5 WeakPolarHBondContact O-CA 3.38Å; K2-Q5 WeakPolarHBondContact O-CB 3.29Å; K2-Q5 PolarHBondContact O-N 3.49Å; L3-Q5 PolarHBondContact O-N 3.46Å; Q5-V9 WeakPolarHBondContact O-CG2 3.12Å; Q5-V9 PolarHBondContact O-N 3.11Å; Q5-V9 VanDerWaalsContact O-N 3.16Å
6R72.1Confident72.1Confident168 Ų168117.3 Ų117.363%0.63460%0.598SS**Hα-helixtrans-68.7-38.7175.4-72.4-177173.3173.6-1.6111.7M1 K2 L3 V9 L10M1-R6 HydrophobicContact CB-CG 4.33Å; K2-R6 PolarHBondContact O-N 3.4Å; L3-R6 PolarHBondContact O-N 3.33Å; R6-V9 PolarHBondContact O-N 2.85Å; R6-L10 WeakPolarHBondContact O-CB 3.36Å; R6-L10 PolarHBondContact O-N 2.97Å
7M70.6Confident71.9Confident130 Ų130116.8 Ų116.864%0.6460%0.596SS**Hα-helixtrans-65.4-40.1176.5-122.8-173.584.600112.5L3 K4 L10 C11L3-M7 PolarHBondContact O-N 3.19Å; L3-M7 VanDerWaalsContact O-N 3.11Å; K4-M7 PolarHBondContact O-N 3.13Å; M7-L10 PolarHBondContact O-N 3.06Å; M7-C11 WeakPolarHBondContact O-CB 3.45Å; M7-C11 PolarHBondContact O-N 3.31Å; M7-C11 PolarHBondContact O-SG 3.09Å
8V76Confident71.5Confident103 Ų103112 Ų11262%0.62458%0.581SS**Hα-helixtrans-66-42.6177.61720000111.2K4 C11 A12K4-V8 VanDerWaalsContact O-CG2 3.32Å; K4-V8 WeakPolarHBondContact O-CG2 3.34Å; K4-V8 PolarHBondContact O-N 3.08Å; K4-V8 VanDerWaalsContact O-N 3.12Å; V8-C11 PolarHBondContact O-N 3.14Å; V8-A12 WeakPolarHBondContact O-CB 3.37Å; V8-A12 PolarHBondContact O-N 3.35Å
9V75.3Confident70.9Confident77 Ų77110.7 Ų110.747%0.46757%0.574SS.*Hα-helixtrans-66.2-40.8176.4173.10000111.2M1 Q5 R6 A12 V13M1-V9 HydrophobicContact CE-CG2 3.8Å; Q5-V9 WeakPolarHBondContact O-CG2 3.12Å; Q5-V9 PolarHBondContact O-N 3.11Å; Q5-V9 VanDerWaalsContact O-N 3.16Å; R6-V9 PolarHBondContact O-N 2.85Å; V9-A12 PolarHBondContact O-N 3.38Å; V9-V13 HydrophobicContact CG1-CG2 4.36Å; V9-V13 WeakPolarHBondContact O-CB 3.49Å; V9-V13 VanDerWaalsContact O-CG2 3.27Å; V9-V13 WeakPolarHBondContact O-CG2 3.46Å; V9-V13 PolarHBondContact O-N 3.25Å
10L75.6Confident70.1Confident112 Ų112107.3 Ų107.359%0.58656%0.563SS**Hα-helixtrans-64.6-41.2177.2-159.780.1000111.9R6 M7 V13 L14R6-L10 WeakPolarHBondContact O-CB 3.36Å; R6-L10 PolarHBondContact O-N 2.97Å; M7-L10 PolarHBondContact O-N 3.06Å; L10-V13 PolarHBondContact O-N 2.93Å; L10-L14 HydrophobicContact CG-CD1 4.33Å; L10-L14 WeakPolarHBondContact O-CB 3.45Å; L10-L14 WeakPolarHBondContact O-CG 3.48Å; L10-L14 PolarHBondContact O-N 2.96Å
11C74.5Confident69Low65 Ų65108.9 Ų108.944%0.43957%0.566SS.*Hα-helixtrans-64.7-41.6174.9-70.50000111.6M7 V8 L14 L15M7-C11 WeakPolarHBondContact O-CB 3.45Å; M7-C11 PolarHBondContact O-N 3.31Å; M7-C11 PolarHBondContact O-SG 3.09Å; V8-C11 PolarHBondContact O-N 3.14Å; C11-L14 PolarHBondContact O-N 3.48Å; C11-L15 WeakPolarHBondContact O-CB 3.46Å; C11-L15 PolarHBondContact O-N 2.89Å
12A75.8Confident68.8Low49 Ų49106.9 Ų106.941%0.40556%0.557SS.*Hα-helixtrans-64.3-40.6177.300000112.2V8 V9 L15 L16V8-A12 WeakPolarHBondContact O-CB 3.37Å; V8-A12 PolarHBondContact O-N 3.35Å; V9-A12 PolarHBondContact O-N 3.38Å; A12-L15 PolarHBondContact O-N 3.24Å; A12-L16 WeakPolarHBondContact O-CB 3.28Å; A12-L16 WeakPolarHBondContact O-CG 3.27Å; A12-L16 PolarHBondContact O-N 2.89Å
13V77.9Confident67.8Low70 Ų70106.4 Ų106.442%0.42456%0.555SS.*Hα-helixtrans-67.3-41.1176.3171.50000111.4V9 L10 L16 L17V9-V13 HydrophobicContact CG1-CG2 4.36Å; V9-V13 WeakPolarHBondContact O-CB 3.49Å; V9-V13 VanDerWaalsContact O-CG2 3.27Å; V9-V13 WeakPolarHBondContact O-CG2 3.46Å; V9-V13 PolarHBondContact O-N 3.25Å; L10-V13 PolarHBondContact O-N 2.93Å; V13-L16 PolarHBondContact O-N 3.33Å; V13-L17 HydrophobicContact CG1-CD1 3.88Å; V13-L17 HydrophobicContact CG1-CG 4.44Å; V13-L17 WeakPolarHBondContact O-CB 3.43Å; V13-L17 VanDerWaalsContact O-CG 3.31Å; V13-L17 WeakPolarHBondContact O-CG 3.42Å; V13-L17 PolarHBondContact O-N 3.47Å
14L75.9Confident66.7Low108 Ų108106.2 Ų106.257%0.56555%0.554SS**Hα-helixtrans-67-35.7175.7-75.3166.7000112.3L10 C11 L17 G18L10-L14 HydrophobicContact CG-CD1 4.33Å; L10-L14 WeakPolarHBondContact O-CB 3.45Å; L10-L14 WeakPolarHBondContact O-CG 3.48Å; L10-L14 PolarHBondContact O-N 2.96Å; C11-L14 PolarHBondContact O-N 3.48Å; L14-L17 PolarHBondContact O-N 3.24Å; L14-G18 PolarHBondContact O-N 2.82Å
15L76.6Confident65.6Low118 Ų118104.4 Ų104.462%0.61855%0.552SS**Hα-helixtrans-66.8-42.5173.7-127.3117.6000111.4C11 A12 G18 L19C11-L15 WeakPolarHBondContact O-CB 3.46Å; C11-L15 PolarHBondContact O-N 2.89Å; A12-L15 PolarHBondContact O-N 3.24Å; L15-G18 PolarHBondContact O-N 2.75Å; L15-L19 HydrophobicContact CD2-CD1 4.24Å; L15-L19 WeakPolarHBondContact O-CB 3.29Å; L15-L19 VanDerWaalsContact O-CG 3.29Å; L15-L19 WeakPolarHBondContact O-CG 3.37Å; L15-L19 PolarHBondContact O-N 3.15Å
16L72.6Confident64.2Low117 Ų117104.8 Ų104.861%0.61356%0.557SS**Hα-helixtrans-65.5-39.5175.8-79163.6000112A12 V13 A20A12-L16 WeakPolarHBondContact O-CB 3.28Å; A12-L16 WeakPolarHBondContact O-CG 3.27Å; A12-L16 PolarHBondContact O-N 2.89Å; V13-L16 PolarHBondContact O-N 3.33Å; L16-A20 WeakPolarHBondContact O-CB 3.25Å; L16-A20 PolarHBondContact O-N 3.47Å
17L68.8Low62.6Low108 Ų10899.9 Ų99.957%0.56556%0.559SS**Hα-helixtrans-68.9-36.9174.3-74.1168000111.9V13 L14 K21V13-L17 HydrophobicContact CG1-CD1 3.88Å; V13-L17 HydrophobicContact CG1-CG 4.44Å; V13-L17 WeakPolarHBondContact O-CB 3.43Å; V13-L17 VanDerWaalsContact O-CG 3.31Å; V13-L17 WeakPolarHBondContact O-CG 3.42Å; V13-L17 PolarHBondContact O-N 3.47Å; L14-L17 PolarHBondContact O-N 3.24Å; L17-K21 VanDerWaalsContact O-CB 3.27Å; L17-K21 WeakPolarHBondContact O-CB 3.43Å; L17-K21 PolarHBondContact O-N 3.3Å
18G64.8Low61Low31 Ų3196.6 Ų96.632%0.3256%0.559SS.*Hα-helixtrans-64.5-45.7172.900000112.2L14 L15 K21 I22L14-G18 PolarHBondContact O-N 2.82Å; L15-G18 PolarHBondContact O-N 2.75Å; G18-K21 PolarHBondContact O-N 3.28Å; G18-I22 VanDerWaalsContact O-CG1 3.28Å; G18-I22 WeakPolarHBondContact O-CG1 3.36Å; G18-I22 PolarHBondContact O-N 3.45Å
19L60.6Low59.4Low87 Ų87100.7 Ų100.746%0.45557%0.571SS.*Hα-helixtrans-66.6-38.1175.5-73.7171000112.3L15 K21 I22 F23L15-L19 HydrophobicContact CD2-CD1 4.24Å; L15-L19 WeakPolarHBondContact O-CB 3.29Å; L15-L19 VanDerWaalsContact O-CG 3.29Å; L15-L19 WeakPolarHBondContact O-CG 3.37Å; L15-L19 PolarHBondContact O-N 3.15Å; L19-K21 VanDerWaalsContact C-N 3.34Å; L19-I22 PolarHBondContact O-N 3.38Å; L19-F23 WeakPolarHBondContact O-CB 3.25Å; L19-F23 PolarHBondContact O-N 2.87Å
20A54Low57.9Low42 Ų4298.3 Ų98.335%0.34756%0.562SS.*Hα-helixtrans-67.1-35.7173.600000111.7L16 F23 L24L16-A20 WeakPolarHBondContact O-CB 3.25Å; L16-A20 PolarHBondContact O-N 3.47Å; A20-F23 PolarHBondContact O-N 3.11Å; A20-L24 WeakPolarHBondContact O-CB 3.35Å; A20-L24 WeakPolarHBondContact O-CD1 3.26Å; A20-L24 VanDerWaalsContact O-CG 3.31Å; A20-L24 WeakPolarHBondContact O-CG 3.32Å; A20-L24 PolarHBondContact O-N 3.42Å
21K47.7Very low56.6Low142 Ų14296.6 Ų96.662%0.61756%0.56SS**Hα-helixtrans-70.9-35.2174.9-154.2179.1-172.8-178.30111.8L17 G18 L19 L25L17-K21 VanDerWaalsContact O-CB 3.27Å; L17-K21 WeakPolarHBondContact O-CB 3.43Å; L17-K21 PolarHBondContact O-N 3.3Å; G18-K21 PolarHBondContact O-N 3.28Å; L19-K21 VanDerWaalsContact C-N 3.34Å; K21-L25 HydrophobicContact CG-CD1 3.86Å; K21-L25 HydrophobicContact CG-CG 4.42Å; K21-L25 WeakPolarHBondContact O-CB 3.49Å; K21-L25 WeakPolarHBondContact O-CD1 3.47Å; K21-L25 WeakPolarHBondContact O-CG 3.36Å; K21-L25 PolarHBondContact O-N 3.45Å
22I51.6Low55.1Low99 Ų9996.7 Ų96.751%0.50857%0.565SS.*Hα-helixtrans-65.9-47.5170.2-67.4163.1000109.5G18 L19 L24 L25 D26G18-I22 VanDerWaalsContact O-CG1 3.28Å; G18-I22 WeakPolarHBondContact O-CG1 3.36Å; G18-I22 PolarHBondContact O-N 3.45Å; L19-I22 PolarHBondContact O-N 3.38Å; I22-L24 VanDerWaalsContact C-N 3.33Å; I22-L24 PolarHBondContact O-N 3.45Å; I22-L25 PolarHBondContact O-N 3.26Å; I22-D26 WeakPolarHBondContact O-CA 3.33Å; I22-D26 WeakPolarHBondContact O-CB 3.18Å; I22-D26 PolarHBondContact O-N 3.37Å
23F48.2Very low53.6Low166 Ų16696.8 Ų96.873%0.72857%0.566SS**Hα-helixtrans-66.5-28.5176.8-100.3-89.1000114.6L19 A20 G27L19-F23 WeakPolarHBondContact O-CB 3.25Å; L19-F23 PolarHBondContact O-N 2.87Å; A20-F23 PolarHBondContact O-N 3.11Å; F23-G27 WeakPolarHBondContact O-CA 3.24Å; F23-G27 PolarHBondContact O-N 2.83Å; F23-G27 VanDerWaalsContact O-N 3.16Å
24L46.6Very low52.3Low148 Ų14896 Ų9678%0.77556%0.564SS**Hα-helixtrans-84.2-26.7176.3-80.6161.6000113.3A20 I22A20-L24 WeakPolarHBondContact O-CB 3.35Å; A20-L24 WeakPolarHBondContact O-CD1 3.26Å; A20-L24 VanDerWaalsContact O-CG 3.31Å; A20-L24 WeakPolarHBondContact O-CG 3.32Å; A20-L24 PolarHBondContact O-N 3.42Å; I22-L24 VanDerWaalsContact C-N 3.33Å; I22-L24 PolarHBondContact O-N 3.45Å
25L45Very low51.2Low141 Ų14198.7 Ų98.774%0.73857%0.566SS**Hα-helixtrans-89.9-24.4175.1-69.2169.9000112.6K21 I22K21-L25 HydrophobicContact CG-CD1 3.86Å; K21-L25 HydrophobicContact CG-CG 4.42Å; K21-L25 WeakPolarHBondContact O-CB 3.49Å; K21-L25 WeakPolarHBondContact O-CD1 3.47Å; K21-L25 WeakPolarHBondContact O-CG 3.36Å; K21-L25 PolarHBondContact O-N 3.45Å; I22-L25 PolarHBondContact O-N 3.26Å
26D39.2Very low50.3Low119 Ų119102 Ų10264%0.63657%0.571SS**SBendtrans-103.82.7-179.7-137.712.4000112I22 G28I22-D26 WeakPolarHBondContact O-CA 3.33Å; I22-D26 WeakPolarHBondContact O-CB 3.18Å; I22-D26 PolarHBondContact O-N 3.37Å; D26-G28 VanDerWaalsContact C-N 3.28Å; D26-G28 PolarHBondContact O-N 3.29Å
27G36.9Very low49.5Very low65 Ų6599.6 Ų99.667%0.6756%0.558SS**SBendtrans-7965.5175.100000112.5F23F23-G27 WeakPolarHBondContact O-CA 3.24Å; F23-G27 PolarHBondContact O-N 2.83Å; F23-G27 VanDerWaalsContact O-N 3.16Å
28G38.1Very low49.2Very low61 Ų6198.9 Ų98.963%0.62956%0.555SS**SBendtrans166.2-10.6168.300000118.9D26 G30D26-G28 VanDerWaalsContact C-N 3.28Å; D26-G28 PolarHBondContact O-N 3.29Å; G28-G30 PolarHBondContact O-N 2.8Å
29E42Very low49.3Very low189 Ų189106.8 Ų106.888%0.88358%0.575SS**SBendtrans-98.492.5-179.5-70.4-164156.200111.4
30G43.4Very low49.4Very low28 Ų28105.5 Ų105.529%0.28958%0.576SS.*  trans135.121161.100000117.8G28 R35G28-G30 PolarHBondContact O-N 2.8Å; G30-R35 PolarHBondContact O-NE 3.25Å; G30-R35 PolarHBondContact O-NH2 3.5Å
31S47.8Very low49.9Very low75 Ų75105.9 Ų105.952%0.52457%0.57SS.*  trans-55.4143.2163.2173.10000110.4A33 S34 R35S31-A33 PolarHBondContact O-N 2.87Å; S31-A33 VanDerWaalsContact O-N 3.17Å; S31-A33 PolarHBondContact OG-N 3.46Å; S31-S34 PolarHBondContact O-N 2.99Å; S31-R35 PolarHBondContact O-N 2.9Å
32A44.5Very low50.9Low67 Ų67107 Ų10755%0.55457%0.571SS**Hα-helixtrans-56.8-27.117300000112.2R36A32-R36 WeakPolarHBondContact O-CB 3.26Å; A32-R36 VanDerWaalsContact O-CG 3.27Å; A32-R36 WeakPolarHBondContact O-CG 3.26Å; A32-R36 PolarHBondContact O-N 2.67Å
33A43.3Very low51.7Low51 Ų51106.4 Ų106.442%0.42156%0.564SS.*Hα-helixtrans-64.1-54.317100000111S31 R35 R36 D37S31-A33 PolarHBondContact O-N 2.87Å; S31-A33 VanDerWaalsContact O-N 3.17Å; S31-A33 PolarHBondContact OG-N 3.46Å; A33-R35 VanDerWaalsContact C-N 3.29Å; A33-R35 PolarHBondContact O-N 3.04Å; A33-R36 WeakPolarHBondContact O-CB 3.31Å; A33-R36 PolarHBondContact O-N 3.16Å; A33-D37 WeakPolarHBondContact O-CB 3.49Å; A33-D37 PolarHBondContact O-N 2.88Å; A33-D37 VanDerWaalsContact O-OD2 3.11Å
34S50.6Low52.6Low54 Ų5498.9 Ų98.938%0.37853%0.531SS..Hα-helixtrans-56.8-38.1177.2170.10000113.2S31 D37 L38S31-S34 PolarHBondContact O-N 2.99Å; S34-D37 PolarHBondContact O-N 3.24Å; S34-L38 WeakPolarHBondContact O-CB 3.43Å; S34-L38 PolarHBondContact O-N 3.33Å
35R53.1Low53.6Low164 Ų16496.4 Ų96.462%0.61952%0.516SS*.Hα-helixtrans-70.8-34.4174.8-81.9-174.7-101.5-172.7-9113.7G30 S31 A33 R39G30-R35 PolarHBondContact O-NE 3.25Å; G30-R35 PolarHBondContact O-NH2 3.5Å; S31-R35 PolarHBondContact O-N 2.9Å; A33-R35 VanDerWaalsContact C-N 3.29Å; A33-R35 PolarHBondContact O-N 3.04Å; R35-R39 WeakPolarHBondContact O-CG 2.96Å; R35-R39 PolarHBondContact O-N 3.08Å
36R57.5Low54.7Low189 Ų18993.9 Ų93.971%0.71351%0.51SS*.Hα-helixtrans-69.3-41.4173.1-77.2176.1-176-169.11.7110.7A32 A33 R39 A40A32-R36 WeakPolarHBondContact O-CB 3.26Å; A32-R36 VanDerWaalsContact O-CG 3.27Å; A32-R36 WeakPolarHBondContact O-CG 3.26Å; A32-R36 PolarHBondContact O-N 2.67Å; A33-R36 WeakPolarHBondContact O-CB 3.31Å; A33-R36 PolarHBondContact O-N 3.16Å; R36-R39 PolarHBondContact O-N 2.94Å; R36-A40 WeakPolarHBondContact O-CB 3.47Å; R36-A40 PolarHBondContact O-N 2.89Å
37D56.6Low56Low66 Ų6689.6 Ų89.635%0.35349%0.494SS..Hα-helixtrans-63-43.3177.9-63.4-23.4000111.5A33 S34 R39 A40 F41 F346A33-D37 WeakPolarHBondContact O-CB 3.49Å; A33-D37 PolarHBondContact O-N 2.88Å; A33-D37 VanDerWaalsContact O-OD2 3.11Å; S34-D37 PolarHBondContact O-N 3.24Å; D37-R39 PolarHBondContact O-N 3.03Å; D37-A40 PolarHBondContact O-N 3.24Å; D37-F41 WeakPolarHBondContact O-CB 3.43Å; D37-F41 PolarHBondContact O-N 2.76Å; D37-F346 HydrophobicContact CB-CE1 3.74Å; D37-F346 HydrophobicContact CB-CZ 3.71Å
38L61.3Low57.5Low93 Ų9387 Ų8749%0.48747%0.465SS..Hα-helixtrans-66.2-36176.1-153.786.7000112.7S34 R42S34-L38 WeakPolarHBondContact O-CB 3.43Å; S34-L38 PolarHBondContact O-N 3.33Å; L38-R42 WeakPolarHBondContact O-CG 3.45Å; L38-R42 PolarHBondContact O-N 3.45Å
39R66.6Low59.2Low197 Ų19787.2 Ų87.274%0.74346%0.456SS*.Hα-helixtrans-68.9-42.1174.7-77.8-179-177.3-1620.8111.6R35 R36 D37 F41 R42 K43R35-R39 WeakPolarHBondContact O-CG 2.96Å; R35-R39 PolarHBondContact O-N 3.08Å; R36-R39 PolarHBondContact O-N 2.94Å; D37-R39 PolarHBondContact O-N 3.03Å; R39-F41 VanDerWaalsContact C-N 3.3Å; R39-F41 PolarHBondContact O-N 3.37Å; R39-R42 PolarHBondContact O-N 3.25Å; R39-K43 WeakPolarHBondContact O-CB 3.43Å; R39-K43 PolarHBondContact O-N 3.23Å
40A63.6Low61Low59 Ų5980 Ų8049%0.48842%0.424SS..Hα-helixtrans-61.1-42.1174.700000111R36 D37 K43 M44R36-A40 WeakPolarHBondContact O-CB 3.47Å; R36-A40 PolarHBondContact O-N 2.89Å; D37-A40 PolarHBondContact O-N 3.24Å; A40-K43 PolarHBondContact O-N 2.68Å; A40-M44 PolarHBondContact O-N 3.11Å
41F65.4Low62.7Low50 Ų5082.5 Ų82.522%0.21944%0.435CS..Hα-helixtrans-61.8-48.5174.6-172.7-90.2000112.6D37 R39 K43 M44 E45 I158 V351D37-F41 WeakPolarHBondContact O-CB 3.43Å; D37-F41 PolarHBondContact O-N 2.76Å; R39-F41 VanDerWaalsContact C-N 3.3Å; R39-F41 PolarHBondContact O-N 3.37Å; F41-K43 PolarHBondContact O-N 2.89Å; F41-M44 HydrophobicContact CB-CE 4.44Å; F41-M44 HydrophobicContact CD1-CE 4.2Å; F41-M44 HydrophobicContact CD2-CE 3.26Å; F41-M44 HydrophobicContact CE1-CE 4.24Å; F41-M44 HydrophobicContact CE2-CE 3.32Å; F41-M44 HydrophobicContact CG-CE 3.73Å; F41-M44 HydrophobicContact CZ-CE 3.83Å; F41-M44 WeakPolarHBondContact O-CA 3.13Å; F41-M44 VanDerWaalsContact O-CB 3.31Å; F41-M44 WeakPolarHBondContact O-CB 3.46Å; F41-M44 WeakPolarHBondContact O-CE 3.11Å; F41-M44 PolarHBondContact O-N 2.87Å; F41-M44 VanDerWaalsContact O-N 3.08Å; F41-E45 HydrophobicContact CD1-CG 4.33Å; F41-E45 VanDerWaalsContact CE1-CD 3.47Å; F41-E45 HydrophobicContact CE1-CG 3.86Å; F41-E45 WeakPolarHBondContact CE1-OE1 3.24Å; F41-E45 HydrophobicContact CZ-CG 4.34Å; F41-E45 PolarHBondContact O-N 2.96Å; F41-I158 HydrophobicContact CE2-CD1 4.48Å; F41-V351 HydrophobicContact CE2-CG1 3.89Å; F41-V351 HydrophobicContact CZ-CG1 4.17Å
42R67.9Low64Low166 Ų16688.2 Ų88.263%0.62645%0.445SS*.Hα-helixtrans-63.6-39.5177.4-74.7-179.4-179.7176.91113L38 R39 M44 E45 S46L38-R42 WeakPolarHBondContact O-CG 3.45Å; L38-R42 PolarHBondContact O-N 3.45Å; R39-R42 PolarHBondContact O-N 3.25Å; R42-M44 PolarHBondContact O-N 3.22Å; R42-E45 PolarHBondContact O-N 2.88Å; R42-S46 PolarHBondContact O-N 2.68Å; R42-S46 PolarHBondContact O-OG 3.39Å
43K68.8Low65.2Low87 Ų8787.4 Ų87.438%0.37844%0.443SS..Hα-helixtrans-61.8-37.1173.6-171.8178.1-179.3-1730110.6R39 A40 F41 S46 G47 E80R39-K43 WeakPolarHBondContact O-CB 3.43Å; R39-K43 PolarHBondContact O-N 3.23Å; A40-K43 PolarHBondContact O-N 2.68Å; F41-K43 PolarHBondContact O-N 2.89Å; K43-S46 PolarHBondContact O-OG 2.81Å; K43-G47 PolarHBondContact O-N 2.81Å; K43-E80 WeakPolarHBondContact CE-OE1 3.38Å; K43-E80 IonicContact NZ-OE1 3.12Å; K43-E80 PolarHBondContact NZ-OE1 3.5Å
44M67.3Low66.9Low7 Ų786 Ų863%0.03443%0.431CS..Hα-helixtrans-62.9-55.3172171-107.6-25.600112.5A40 F41 R42 S46 G47 L48 R157 I158A40-M44 PolarHBondContact O-N 3.11Å; F41-M44 HydrophobicContact CB-CE 4.44Å; F41-M44 HydrophobicContact CD1-CE 4.2Å; F41-M44 HydrophobicContact CD2-CE 3.26Å; F41-M44 HydrophobicContact CE1-CE 4.24Å; F41-M44 HydrophobicContact CE2-CE 3.32Å; F41-M44 HydrophobicContact CG-CE 3.73Å; F41-M44 HydrophobicContact CZ-CE 3.83Å; F41-M44 WeakPolarHBondContact O-CA 3.13Å; F41-M44 VanDerWaalsContact O-CB 3.31Å; F41-M44 WeakPolarHBondContact O-CB 3.46Å; F41-M44 WeakPolarHBondContact O-CE 3.11Å; F41-M44 PolarHBondContact O-N 2.87Å; F41-M44 VanDerWaalsContact O-N 3.08Å; R42-M44 PolarHBondContact O-N 3.22Å; M44-S46 PolarHBondContact O-N 2.97Å; M44-G47 CarbonylContact O-C 3.27Å; M44-G47 WeakPolarHBondContact O-CA 3.47Å; M44-G47 PolarHBondContact O-N 3.25Å; M44-L48 HydrophobicContact CG-CG 4.36Å; M44-L48 PolarHBondContact O-N 3.47Å; M44-L48 VanDerWaalsContact O-N 3.17Å; M44-L48 HydrophobicContact SD-CD1 3.67Å; M44-L48 HydrophobicContact SD-CD2 4.4Å; M44-L48 HydrophobicContact SD-CG 4.09Å; M44-R157 HydrophobicContact CB-CB 4.33Å; M44-R157 HydrophobicContact CG-CB 3.86Å; M44-I158 HydrophobicContact CB-CG1 4.24Å; M44-I158 HydrophobicContact CE-CD1 3.14Å; M44-I158 HydrophobicContact CE-CG1 3.69Å; M44-I158 HydrophobicContact CG-CD1 4.13Å; M44-I158 HydrophobicContact CG-CG1 3.64Å; M44-I158 HydrophobicContact SD-CD1 3.42Å; M44-I158 WeakPolarHBondContact SD-CD1 3.41Å; M44-I158 HydrophobicContact SD-CG1 3.66Å
45E66.3Low68.2Low97 Ų9789.9 Ų89.945%0.45344%0.443SS..Hα-helixtrans-54.1-40.7-179.5-78.2-172.8144.900111.8F41 R42 G47 L48F41-E45 HydrophobicContact CD1-CG 4.33Å; F41-E45 VanDerWaalsContact CE1-CD 3.47Å; F41-E45 HydrophobicContact CE1-CG 3.86Å; F41-E45 WeakPolarHBondContact CE1-OE1 3.24Å; F41-E45 HydrophobicContact CZ-CG 4.34Å; F41-E45 PolarHBondContact O-N 2.96Å; R42-E45 PolarHBondContact O-N 2.88Å; E45-G47 PolarHBondContact O-N 2.98Å; E45-L48 PolarHBondContact O-N 3.28Å
46S67.6Low69.5Low87 Ų8784.4 Ų84.461%0.60843%0.426SS*.Hα-helixtrans-64.4-24.3177.171.40000114.2R42 K43 M44R42-S46 PolarHBondContact O-N 2.68Å; R42-S46 PolarHBondContact O-OG 3.39Å; K43-S46 PolarHBondContact O-OG 2.81Å; M44-S46 PolarHBondContact O-N 2.97Å
47G66.5Low70Confident29 Ų2980.6 Ų80.630%0.29942%0.424SS..Hα-helixtrans-94.7-6.8178.500000114.9K43 M44 E45K43-G47 PolarHBondContact O-N 2.81Å; M44-G47 CarbonylContact O-C 3.27Å; M44-G47 WeakPolarHBondContact O-CA 3.47Å; M44-G47 PolarHBondContact O-N 3.25Å; E45-G47 PolarHBondContact O-N 2.98Å
48L69.6Low70.3Confident12 Ų1285.8 Ų85.86%0.06345%0.446CS..Hα-helixtrans-76.2-29.5177.6-69.2176.3000112.4M44 E45 L156 A355 Q358M44-L48 HydrophobicContact CG-CG 4.36Å; M44-L48 PolarHBondContact O-N 3.47Å; M44-L48 VanDerWaalsContact O-N 3.17Å; M44-L48 HydrophobicContact SD-CD1 3.67Å; M44-L48 HydrophobicContact SD-CD2 4.4Å; M44-L48 HydrophobicContact SD-CG 4.09Å; E45-L48 PolarHBondContact O-N 3.28Å; L48-L156 HydrophobicContact CD2-CD1 4.38Å; L48-L156 HydrophobicContact CD2-CG 3.91Å; L48-A355 HydrophobicContact CD1-CB 3.61Å; L48-A355 HydrophobicContact CD2-CB 4.41Å; L48-Q358 HydrophobicContact CB-CG 4.35Å
49S73.5Confident70.6Confident64 Ų6484.2 Ų84.245%0.44844%0.44SS..SBendtrans-92.5109.6179.5-63.90000110.3Q358S49-Q358 PolarHBondContact OG-NE2 3.07Å
50L80.3Confident71Confident38 Ų3883.9 Ų83.920%0.19945%0.452CS..PPolyproline II helixtrans-84.6136.4172.1-65.2179.4000110.4R52 L84 A85 L88 F362L50-R52 PolarHBondContact O-N 2.92Å; L50-L84 HydrophobicContact CD1-CD2 4.07Å; L50-L84 HydrophobicContact CD1-CG 4.31Å; L50-L84 HydrophobicContact CD2-CD2 4.11Å; L50-A85 HydrophobicContact CB-CB 3.97Å; L50-A85 HydrophobicContact CD2-CB 4.25Å; L50-A85 HydrophobicContact CG-CB 4.48Å; L50-L88 HydrophobicContact CD1-CD1 3.83Å; L50-F362 HydrophobicContact CB-CB 4.29Å; L50-F362 HydrophobicContact CB-CD1 4.31Å; L50-F362 HydrophobicContact CB-CD2 3.46Å; L50-F362 VanDerWaalsContact CB-CD2 3.46Å; L50-F362 HydrophobicContact CB-CE2 3.79Å; L50-F362 HydrophobicContact CB-CG 3.75Å; L50-F362 HydrophobicContact CB-CZ 4.35Å; L50-F362 HydrophobicContact CD1-CD1 3.9Å; L50-F362 HydrophobicContact CD1-CE1 4.11Å; L50-F362 HydrophobicContact CD1-CG 4.13Å; L50-F362 HydrophobicContact CG-CG 4.5Å
51P78.6Confident71.9Confident81 Ų8185.1 Ų85.153%0.52645%0.447SS..PPolyproline II helixtrans-66128177.225-32000110.7A54 A85 F362P51-A54 HydrophobicContact CG-CB 4.21Å; P51-A85 HydrophobicContact CG-CB 3.96Å; P51-F362 WeakPolarHBondContact O-CE2 3.36Å
52R74.1Confident73Confident195 Ų19584.4 Ų84.474%0.73645%0.449SS*.THydrogen-bonded Turntrans-71.5142.6174.1-69.3-175.9179174.5-0.9110.7L50 A54 A361 F362L50-R52 PolarHBondContact O-N 2.92Å; R52-A54 VanDerWaalsContact C-N 3.27Å; R52-A54 PolarHBondContact O-N 2.84Å; R52-A361 PolarHBondContact NH2-O 2.96Å; R52-F362 HydrophobicContact CG-CD2 4.4Å
53G69.9Low74.2Confident49 Ų4977.6 Ų77.651%0.50543%0.426SS..THydrogen-bonded Turntrans68.427.4-179.600000113.2H55G53-H55 PolarHBondContact O-CD2 2.91Å; G53-H55 PolarHBondContact O-N 3.36Å; G53-H55 PolarHBondContact O-NE2 2.61Å
54A79.3Confident75.4Confident21 Ų2174.2 Ų74.217%0.17441%0.411CS..  trans-66.5132.1173.900000110.1P51 R52 A85 A86P51-A54 HydrophobicContact CG-CB 4.21Å; R52-A54 VanDerWaalsContact C-N 3.27Å; R52-A54 PolarHBondContact O-N 2.84Å; A54-A85 HydrophobicContact CB-CB 3.64Å; A54-A86 HydrophobicContact CB-CB 4.17Å; A54-A86 WeakPolarHBondContact O-CA 3.29Å
55H78.7Confident76.6Confident136 Ų13678.6 Ų78.663%0.6343%0.431SS*.  trans-129.7149.9177-63.9-65.2000109.4G53 T57G53-H55 PolarHBondContact O-CD2 2.91Å; G53-H55 PolarHBondContact O-N 3.36Å; G53-H55 PolarHBondContact O-NE2 2.61Å; H55-T57 PolarHBondContact O-N 3.3Å; H55-T57 VanDerWaalsContact O-N 3.13Å
56L80.6Confident77.8Confident49 Ų4974.5 Ų74.526%0.25741%0.412SS..  trans-71.9104.1171.8-63.4173.3000108.1P63 I66 E83 A86L56-P63 HydrophobicContact CD1-CB 3.84Å; L56-P63 HydrophobicContact CD1-CG 4.42Å; L56-I66 HydrophobicContact CD1-CD1 3.73Å; L56-I66 HydrophobicContact CD2-CD1 3.8Å; L56-I66 HydrophobicContact CG-CD1 4.43Å; L56-E83 HydrophobicContact CD2-CB 4.06Å; L56-E83 HydrophobicContact CD2-CG 4.08Å; L56-A86 HydrophobicContact CD2-CB 3.91Å; L56-A86 HydrophobicContact CG-CB 4.04Å
57T66.7Low79Confident110 Ų11070.6 Ų70.668%0.67539%0.386SS*.SBendtrans-91.1-14.3-174.348.50000113.8H55H55-T57 PolarHBondContact O-N 3.3Å; H55-T57 VanDerWaalsContact O-N 3.13Å
58H64.6Low80.3Confident175 Ų17571.4 Ų71.481%0.8139%0.386SS*.SBendtrans-141.824.5-168.9-64.7-65.5000115.1
59T65.8Low81.4Confident60 Ų6076.8 Ų76.837%0.36841%0.411SS..  trans-126.2130.5179.9640000111.4Q61 I66T59-Q61 PolarHBondContact OG1-O 3.02Å; T59-I66 HydrophobicContact CG2-CD1 4.32Å
60L75.8Confident82.3Confident190 Ų19075.4 Ų75.4100%0.99540%0.396SS*.SBendtrans-74-13163.8-69.1172.2000111.9
61Q81.7Confident82.9Confident84 Ų8474.2 Ų74.239%0.39339%0.391SS..SBendtrans-75.4144.4179-68.4177.1-42.900111.3T59 E65 I66T59-Q61 PolarHBondContact OG1-O 3.02Å; Q61-E65 WeakPolarHBondContact CA-OE2 3.18Å; Q61-I66 HydrophobicContact CB-CD1 4.47Å; Q61-I66 HydrophobicContact CB-CG1 4.12Å
62S89.9Confident83.4Confident35 Ų3571 Ų7125%0.24537%0.372CS..  trans-70.4151.7173.587.70000110.6W64 E65 I66S62-W64 PolarHBondContact O-N 3.12Å; S62-W64 VanDerWaalsContact O-N 3.11Å; S62-W64 PolarHBondContact OG-N 2.89Å; S62-E65 PolarHBondContact N-OE2 2.83Å; S62-E65 PolarHBondContact O-N 3.48Å; S62-E65 VanDerWaalsContact O-N 3.14Å; S62-E65 WeakPolarHBondContact OG-CG 3.33Å; S62-E65 PolarHBondContact OG-N 2.86Å; S62-E65 VanDerWaalsContact OG-N 3.09Å; S62-I66 PolarHBondContact O-N 2.91Å
63P92.4Very high84.1Confident23 Ų2364.6 Ų64.615%0.14936%0.356CS..Hα-helixtrans-57.3-26.8174.321.8-32000112.7L56 A67 V87L56-P63 HydrophobicContact CD1-CB 3.84Å; L56-P63 HydrophobicContact CD1-CG 4.42Å; P63-A67 WeakPolarHBondContact O-CB 3.22Å; P63-A67 PolarHBondContact O-N 2.8Å; P63-A67 VanDerWaalsContact O-N 3.11Å; P63-V87 HydrophobicContact CB-CG2 4.16Å
64W93.6Very high84.9Confident17 Ų1763.9 Ų63.96%0.06434%0.338CS..Hα-helixtrans-75.7-37.8179.9-37.6137.1000112.2S62 A67 S68 L91 A94 L114 D115 Q118 L225S62-W64 PolarHBondContact O-N 3.12Å; S62-W64 VanDerWaalsContact O-N 3.11Å; S62-W64 PolarHBondContact OG-N 2.89Å; W64-A67 PolarHBondContact O-N 3.1Å; W64-S68 VanDerWaalsContact O-CB 3.27Å; W64-S68 WeakPolarHBondContact O-CB 3.45Å; W64-S68 PolarHBondContact O-N 3.38Å; W64-L91 HydrophobicContact CZ3-CB 4.37Å; W64-L91 HydrophobicContact CZ3-CD1 4.38Å; W64-A94 HydrophobicContact CH2-CB 4.15Å; W64-A94 HydrophobicContact CZ2-CB 3.8Å; W64-L114 HydrophobicContact CH2-CD1 4.15Å; W64-L114 HydrophobicContact CZ2-CB 4.47Å; W64-L114 HydrophobicContact CZ2-CD1 4.19Å; W64-D115 PolarHBondContact NE1-O 3.09Å; W64-Q118 HydrophobicContact CB-CB 4.16Å; W64-Q118 HydrophobicContact CB-CG 4.08Å; W64-Q118 VanDerWaalsContact CD1-CB 3.48Å; W64-Q118 HydrophobicContact CD2-CB 3.93Å; W64-Q118 HydrophobicContact CD2-CG 3.87Å; W64-Q118 HydrophobicContact CE3-CG 4.28Å; W64-Q118 HydrophobicContact CG-CB 3.59Å; W64-Q118 HydrophobicContact CG-CG 3.77Å; W64-L225 HydrophobicContact CE3-CD1 4.36Å
65E92.3Very high85.4Confident98 Ų9865.7 Ų65.746%0.45834%0.343SS..Hα-helixtrans-65-43.1174.7-72.9169.117100111Q61 S62 S68 Q69Q61-E65 WeakPolarHBondContact CA-OE2 3.18Å; S62-E65 PolarHBondContact N-OE2 2.83Å; S62-E65 PolarHBondContact O-N 3.48Å; S62-E65 VanDerWaalsContact O-N 3.14Å; S62-E65 WeakPolarHBondContact OG-CG 3.33Å; S62-E65 PolarHBondContact OG-N 2.86Å; S62-E65 VanDerWaalsContact OG-N 3.09Å; E65-S68 PolarHBondContact O-N 2.93Å; E65-Q69 VanDerWaalsContact O-CG 3.29Å; E65-Q69 WeakPolarHBondContact O-CG 3.26Å; E65-Q69 PolarHBondContact O-N 2.89Å
66I92.5Very high86Confident11 Ų1159.5 Ų59.56%0.05632%0.315CS..Hα-helixtrans-58.8-50.7175.1-63.9171.5000109.7L56 T59 Q61 S62 S68 Q69 W70 E83L56-I66 HydrophobicContact CD1-CD1 3.73Å; L56-I66 HydrophobicContact CD2-CD1 3.8Å; L56-I66 HydrophobicContact CG-CD1 4.43Å; T59-I66 HydrophobicContact CG2-CD1 4.32Å; Q61-I66 HydrophobicContact CB-CD1 4.47Å; Q61-I66 HydrophobicContact CB-CG1 4.12Å; S62-I66 PolarHBondContact O-N 2.91Å; I66-S68 VanDerWaalsContact C-N 3.31Å; I66-S68 PolarHBondContact O-N 3.32Å; I66-Q69 PolarHBondContact O-N 2.89Å; I66-W70 HydrophobicContact CG2-CH2 4.32Å; I66-W70 HydrophobicContact CG2-CZ2 3.49Å; I66-W70 VanDerWaalsContact CG2-CZ2 3.49Å; I66-W70 PolarHBondContact O-N 3.19Å; I66-E83 HydrophobicContact CG2-CB 4.35Å; I66-E83 HydrophobicContact CG2-CG 4.49Å
67A93.3Very high86.4Confident6 Ų657.3 Ų57.35%0.0530%0.303CS..Hα-helixtrans-63.1-35.8179.400000113.2P63 W64 W70 V87 L166 L225P63-A67 WeakPolarHBondContact O-CB 3.22Å; P63-A67 PolarHBondContact O-N 2.8Å; P63-A67 VanDerWaalsContact O-N 3.11Å; W64-A67 PolarHBondContact O-N 3.1Å; A67-W70 HydrophobicContact CB-CE3 4.12Å; A67-W70 HydrophobicContact CB-CZ3 4.18Å; A67-W70 WeakPolarHBondContact O-CB 3.35Å; A67-W70 PolarHBondContact O-N 2.82Å; A67-V87 HydrophobicContact CB-CG1 4.07Å; A67-L166 HydrophobicContact CB-CD1 4.22Å; A67-L225 HydrophobicContact CB-CD2 3.82Å
68S93.3Very high87.4Confident45 Ų4553.7 Ų53.732%0.31528%0.282SS..Hα-helixtrans-65-40176.9179.70000112.2W64 E65 I66 W70 V71 P228W64-S68 VanDerWaalsContact O-CB 3.27Å; W64-S68 WeakPolarHBondContact O-CB 3.45Å; W64-S68 PolarHBondContact O-N 3.38Å; E65-S68 PolarHBondContact O-N 2.93Å; I66-S68 VanDerWaalsContact C-N 3.31Å; I66-S68 PolarHBondContact O-N 3.32Å; S68-W70 PolarHBondContact O-N 2.88Å; S68-V71 PolarHBondContact O-N 2.99Å; S68-P228 VanDerWaalsContact OG-CB 3.25Å; S68-P228 WeakPolarHBondContact OG-CB 3.45Å
69Q92.8Very high88.3Confident126 Ų12649.6 Ų49.659%0.58926%0.263SS*.Hα-helixtrans-68-19.2179.3-71.6167.620.700113.5E65 I66 V71E65-Q69 VanDerWaalsContact O-CG 3.29Å; E65-Q69 WeakPolarHBondContact O-CG 3.26Å; E65-Q69 PolarHBondContact O-N 2.89Å; I66-Q69 PolarHBondContact O-N 2.89Å; Q69-V71 VanDerWaalsContact C-N 3.35Å
70W92.8Very high89.1Confident34 Ų3452.5 Ų52.513%0.12927%0.272CS..THydrogen-bonded Turntrans-74.4-24.8177.2-65.5-18.7000114.1I66 A67 S68 G72 V76 P78 T81 E83 L84 V87 L166I66-W70 HydrophobicContact CG2-CH2 4.32Å; I66-W70 HydrophobicContact CG2-CZ2 3.49Å; I66-W70 VanDerWaalsContact CG2-CZ2 3.49Å; I66-W70 PolarHBondContact O-N 3.19Å; A67-W70 HydrophobicContact CB-CE3 4.12Å; A67-W70 HydrophobicContact CB-CZ3 4.18Å; A67-W70 WeakPolarHBondContact O-CB 3.35Å; A67-W70 PolarHBondContact O-N 2.82Å; S68-W70 PolarHBondContact O-N 2.88Å; W70-G72 PolarHBondContact O-N 2.85Å; W70-V76 CarbonylContact C-O 3.58Å; W70-P78 HydrophobicContact CG-CG 4.35Å; W70-T81 HydrophobicContact CD2-CG2 4.34Å; W70-T81 HydrophobicContact CE3-CG2 4.48Å; W70-T81 HydrophobicContact CH2-CG2 4.47Å; W70-T81 HydrophobicContact CZ2-CG2 4.28Å; W70-E83 HydrophobicContact CH2-CB 4.45Å; W70-E83 HydrophobicContact CZ2-CB 4.06Å; W70-L84 HydrophobicContact CZ3-CD1 4.38Å; W70-V87 HydrophobicContact CH2-CB 4.33Å; W70-V87 HydrophobicContact CH2-CG2 3.73Å; W70-V87 HydrophobicContact CZ2-CG2 4.5Å; W70-V87 HydrophobicContact CZ3-CG2 4.31Å; W70-L166 HydrophobicContact CZ3-CD1 3.99Å
71V92.6Very high89.5Confident13 Ų1344.6 Ų44.68%0.07923%0.232CC..  trans-73.2124.3-171.9-174.80000109.7S68 Q69 V76 L227 P228 W231 F298S68-V71 PolarHBondContact O-N 2.99Å; Q69-V71 VanDerWaalsContact C-N 3.35Å; V71-V76 HydrophobicContact CG2-CG1 4.31Å; V71-L227 HydrophobicContact CG2-CD2 4.4Å; V71-P228 HydrophobicContact CB-CG 4.2Å; V71-P228 HydrophobicContact CG2-CG 4.02Å; V71-W231 HydrophobicContact CG1-CB 4.4Å; V71-W231 HydrophobicContact CG1-CD2 4.32Å; V71-W231 HydrophobicContact CG1-CG 3.82Å; V71-W231 PolarHBondContact O-NE1 3.37Å; V71-F298 HydrophobicContact CG1-CE1 4.27Å; V71-F298 HydrophobicContact CG1-CE2 3.95Å; V71-F298 HydrophobicContact CG1-CZ 3.49Å; V71-F298 VanDerWaalsContact CG1-CZ 3.49Å
72G89.8Confident89.6Confident14 Ų1445.5 Ų45.514%0.14425%0.245CC..BIsolated β-bridgetrans-134.5177.717600000112.8W70 R74 E75 F298W70-G72 PolarHBondContact O-N 2.85Å; G72-R74 PolarHBondContact O-N 3.31Å; G72-R74 VanDerWaalsContact O-N 3.09Å; G72-E75 PolarHBondContact N-O 2.81Å; G72-E75 VanDerWaalsContact O-O 3.05Å; G72-F298 VanDerWaalsContact O-CE2 3.29Å; G72-F298 WeakPolarHBondContact O-CE2 3.3Å
73P87Confident89.6Confident61 Ų6147.1 Ų47.140%0.39625%0.249SC..THydrogen-bonded Turntrans-60.3-26.3-174.8-23.431.7000114.9W231 M306P73-W231 HydrophobicContact CG-CH2 3.61Å; P73-W231 HydrophobicContact CG-CZ3 4.05Å; P73-M306 WeakPolarHBondContact O-CG 3.45Å; P73-M306 PolarHBondContact O-N 2.76Å
74R87.7Confident89.5Confident33 Ų3346.4 Ų46.413%0.12524%0.243CC..THydrogen-bonded Turntrans-127.52.8-171.6-63.2-58.1-54.7-178.3-0.3114.6G72 D276 A304 M306 M406 L408G72-R74 PolarHBondContact O-N 3.31Å; G72-R74 VanDerWaalsContact O-N 3.09Å; R74-D276 IonicContact CZ-OD1 2.97Å; R74-D276 IonicContact CZ-OD2 3.8Å; R74-D276 VanDerWaalsContact CZ-OD2 3.29Å; R74-D276 IonicContact NH1-OD2 3.39Å; R74-D276 PolarHBondContact NH1-OD2 2.81Å; R74-D276 VanDerWaalsContact NH2-CG 3.3Å; R74-D276 IonicContact NH2-OD1 2.72Å; R74-D276 PolarHBondContact NH2-OD1 3.28Å; R74-D276 IonicContact NH2-OD2 2.83Å; R74-D276 PolarHBondContact NH2-OD2 2.89Å; R74-A304 WeakPolarHBondContact CD-O 3.36Å; R74-A304 PolarHBondContact NH1-O 3.37Å; R74-M306 VanDerWaalsContact NH1-CA 3.3Å; R74-M406 HydrophobicContact CG-CE 4.17Å; R74-L408 HydrophobicContact CG-CD2 4.02Å
75E89.7Confident89.4Confident60 Ų6045.6 Ų45.628%0.2824%0.241SC..BIsolated β-bridgetrans-156142.3172.658-174.5-16800110.6G72 R162 M306G72-E75 PolarHBondContact N-O 2.81Å; G72-E75 VanDerWaalsContact O-O 3.05Å; E75-R162 CarbonylContact C-O 3.59Å; E75-R162 WeakPolarHBondContact CA-O 3.4Å; E75-R162 HydrophobicContact CB-CB 4.23Å; E75-R162 IonicContact OE2-CZ 2.57Å; E75-R162 IonicContact OE2-NE 3.63Å; E75-R162 PolarHBondContact OE2-NE 2.89Å; E75-R162 VanDerWaalsContact OE2-NE 3.1Å; E75-R162 IonicContact OE2-NH2 3.63Å; E75-R162 PolarHBondContact OE2-NH2 2.81Å; E75-M306 VanDerWaalsContact CA-CE 3.41Å
76V91.2Very high89.4Confident6 Ų641.2 Ų41.24%0.03622%0.221CC..SBendtrans-82.7-28.7174.5178.90000110W70 V71 R162 L227 M306W70-V76 CarbonylContact C-O 3.58Å; V71-V76 HydrophobicContact CG2-CG1 4.31Å; V76-R162 PolarHBondContact N-O 3.05Å; V76-L227 HydrophobicContact CG1-CD2 3.96Å; V76-M306 HydrophobicContact CG2-CE 3.63Å
77Y89.9Confident89.4Confident2 Ų240.7 Ų40.71%0.00822%0.219CC..SBendtrans-148149.317750.4-96.5000111.3F151 D154 I155 R162 A164 L166Y77-F151 HydrophobicContact CE1-CE2 4.15Å; Y77-D154 PolarHBondContact OH-OD2 3.07Å; Y77-I155 HydrophobicContact CD2-CD1 3.86Å; Y77-I155 HydrophobicContact CD2-CG1 4.28Å; Y77-I155 HydrophobicContact CE1-CD1 4.26Å; Y77-I155 HydrophobicContact CE2-CB 3.97Å; Y77-I155 HydrophobicContact CE2-CD1 3.34Å; Y77-I155 HydrophobicContact CE2-CG1 3.4Å; Y77-I155 WeakPolarHBondContact OH-CA 3.47Å; Y77-I155 WeakPolarHBondContact OH-CB 3.48Å; Y77-I155 PolarHBondContact OH-N 2.92Å; Y77-I155 VanDerWaalsContact OH-N 3.16Å; Y77-R162 HydrophobicContact CD2-CB 4.05Å; Y77-R162 HydrophobicContact CD2-CG 4.05Å; Y77-R162 HydrophobicContact CE2-CB 3.62Å; Y77-R162 HydrophobicContact CE2-CG 3.48Å; Y77-R162 VanDerWaalsContact CE2-CG 3.48Å; Y77-R162 WeakPolarHBondContact O-CD 3.13Å; Y77-R162 PolarHBondContact O-NE 2.99Å; Y77-R162 WeakPolarHBondContact OH-CA 3.34Å; Y77-A164 WeakPolarHBondContact CE1-O 3.44Å; Y77-L166 HydrophobicContact CD1-CD2 3.9Å; Y77-L166 HydrophobicContact CE1-CD2 4.32Å
78P88.1Confident89.5Confident35 Ų3540.5 Ų40.523%0.22722%0.216CC..  trans-71.3163.5-178.221.6-26.8000112.6W70 E80 T81W70-P78 HydrophobicContact CG-CG 4.35Å; P78-E80 VanDerWaalsContact C-N 3.26Å; P78-E80 PolarHBondContact O-N 3.44Å; P78-T81 HydrophobicContact CB-CG2 4.43Å; P78-T81 VanDerWaalsContact CD-CG2 3.47Å; P78-T81 HydrophobicContact CG-CG2 3.54Å; P78-T81 WeakPolarHBondContact O-CG2 3.43Å
79E81.7Confident89.5Confident88 Ų8839.2 Ų39.241%0.41121%0.207SC..SBendtrans-64.6-30.8177.6-174.4-179.2158.500112.9R157E79-R157 PolarHBondContact O-NH2 3.38Å
80E82.6Confident89.6Confident121 Ų12134.4 Ų34.457%0.56519%0.187SC*.  trans-109.7104.4174-72.5-178.7-169.400108.9K43 P78K43-E80 WeakPolarHBondContact CE-OE1 3.38Å; K43-E80 IonicContact NZ-OE1 3.12Å; K43-E80 PolarHBondContact NZ-OE1 3.5Å; P78-E80 VanDerWaalsContact C-N 3.26Å; P78-E80 PolarHBondContact O-N 3.44Å
81T84.3Confident89.7Confident24 Ų2432.8 Ų32.815%0.14718%0.181CC..  trans-126.874.1-177.733.80000110.5W70 P78 E83 L84W70-T81 HydrophobicContact CD2-CG2 4.34Å; W70-T81 HydrophobicContact CE3-CG2 4.48Å; W70-T81 HydrophobicContact CH2-CG2 4.47Å; W70-T81 HydrophobicContact CZ2-CG2 4.28Å; P78-T81 HydrophobicContact CB-CG2 4.43Å; P78-T81 VanDerWaalsContact CD-CG2 3.47Å; P78-T81 HydrophobicContact CG-CG2 3.54Å; P78-T81 WeakPolarHBondContact O-CG2 3.43Å; T81-E83 PolarHBondContact O-N 3.18Å; T81-L84 VanDerWaalsContact O-CB 3.26Å; T81-L84 WeakPolarHBondContact O-CB 3.43Å; T81-L84 PolarHBondContact O-N 3.44Å; T81-L84 VanDerWaalsContact O-N 3.16Å
82P85.1Confident89.9Confident103 Ų10333.2 Ų33.267%0.66918%0.184SC*.THydrogen-bonded Turntrans-60.9-28-178.920.8-27000113.4
83E89.8Confident90.1Very high69 Ų6937.2 Ų37.232%0.32221%0.206SC..THydrogen-bonded Turntrans-84.8-5.6179.6-52.175.5-169.300113.6L56 I66 W70 T81 A85 A86 V87L56-E83 HydrophobicContact CD2-CB 4.06Å; L56-E83 HydrophobicContact CD2-CG 4.08Å; I66-E83 HydrophobicContact CG2-CB 4.35Å; I66-E83 HydrophobicContact CG2-CG 4.49Å; W70-E83 HydrophobicContact CH2-CB 4.45Å; W70-E83 HydrophobicContact CZ2-CB 4.06Å; T81-E83 PolarHBondContact O-N 3.18Å; E83-A85 VanDerWaalsContact C-N 3.3Å; E83-A85 PolarHBondContact O-N 3.06Å; E83-A86 WeakPolarHBondContact O-CA 3.48Å; E83-A86 WeakPolarHBondContact O-CB 3.22Å; E83-A86 PolarHBondContact O-N 3.36Å; E83-V87 PolarHBondContact O-N 2.93Å
84L89.9Confident90.6Very high8 Ų835.1 Ų35.14%0.04219%0.194CC..Hα-helixtrans-53.4-46.5-177177.666.7000112.3L50 W70 T81 A86 V87 L88 F151 I155 L166L50-L84 HydrophobicContact CD1-CD2 4.07Å; L50-L84 HydrophobicContact CD1-CG 4.31Å; L50-L84 HydrophobicContact CD2-CD2 4.11Å; W70-L84 HydrophobicContact CZ3-CD1 4.38Å; T81-L84 VanDerWaalsContact O-CB 3.26Å; T81-L84 WeakPolarHBondContact O-CB 3.43Å; T81-L84 PolarHBondContact O-N 3.44Å; T81-L84 VanDerWaalsContact O-N 3.16Å; L84-A86 PolarHBondContact O-N 3.17Å; L84-V87 PolarHBondContact O-N 3.08Å; L84-L88 HydrophobicContact CD1-CD1 4.08Å; L84-L88 HydrophobicContact CD1-CG 4.06Å; L84-L88 HydrophobicContact CG-CD1 3.98Å; L84-L88 HydrophobicContact CG-CG 4.31Å; L84-L88 WeakPolarHBondContact O-CG 3.35Å; L84-L88 PolarHBondContact O-N 3.25Å; L84-F151 HydrophobicContact CD1-CZ 4.42Å; L84-I155 HydrophobicContact CD1-CD1 4.18Å; L84-I155 HydrophobicContact CD2-CD1 3.36Å; L84-I155 HydrophobicContact CD2-CG1 4.41Å; L84-I155 HydrophobicContact CG-CD1 4.4Å; L84-L166 HydrophobicContact CD1-CD1 4.47Å; L84-L166 HydrophobicContact CD1-CD2 3.76Å
85A90.5Very high91Very high1 Ų142.1 Ų42.11%0.00822%0.22CC..Hα-helixtrans-60-38.3178.900000111.7L50 P51 A54 E83 T89 F362L50-A85 HydrophobicContact CB-CB 3.97Å; L50-A85 HydrophobicContact CD2-CB 4.25Å; L50-A85 HydrophobicContact CG-CB 4.48Å; P51-A85 HydrophobicContact CG-CB 3.96Å; A54-A85 HydrophobicContact CB-CB 3.64Å; E83-A85 VanDerWaalsContact C-N 3.3Å; E83-A85 PolarHBondContact O-N 3.06Å; A85-T89 VanDerWaalsContact O-CB 3.28Å; A85-T89 WeakPolarHBondContact O-CB 3.4Å; A85-T89 PolarHBondContact O-N 2.87Å; A85-T89 PolarHBondContact O-OG1 2.88Å; A85-F362 HydrophobicContact CB-CE2 4.32Å; A85-F362 HydrophobicContact CB-CZ 4.27Å
86A92.2Very high91.4Very high5 Ų539.5 Ų39.54%0.04121%0.208CC..Hα-helixtrans-72.3-38.2178.800000111.7A54 L56 E83 L84 S90A54-A86 HydrophobicContact CB-CB 4.17Å; A54-A86 WeakPolarHBondContact O-CA 3.29Å; L56-A86 HydrophobicContact CD2-CB 3.91Å; L56-A86 HydrophobicContact CG-CB 4.04Å; E83-A86 WeakPolarHBondContact O-CA 3.48Å; E83-A86 WeakPolarHBondContact O-CB 3.22Å; E83-A86 PolarHBondContact O-N 3.36Å; L84-A86 PolarHBondContact O-N 3.17Å; A86-S90 WeakPolarHBondContact O-CB 3.49Å; A86-S90 PolarHBondContact O-N 2.85Å; A86-S90 PolarHBondContact O-OG 3.43Å
87V94Very high91.7Very high1 Ų143.2 Ų43.21%0.00623%0.225CC..Hα-helixtrans-65.5-46.8175.2175.60000111.1P63 A67 W70 E83 L84 S90 L91 L166P63-V87 HydrophobicContact CB-CG2 4.16Å; A67-V87 HydrophobicContact CB-CG1 4.07Å; W70-V87 HydrophobicContact CH2-CB 4.33Å; W70-V87 HydrophobicContact CH2-CG2 3.73Å; W70-V87 HydrophobicContact CZ2-CG2 4.5Å; W70-V87 HydrophobicContact CZ3-CG2 4.31Å; E83-V87 PolarHBondContact O-N 2.93Å; L84-V87 PolarHBondContact O-N 3.08Å; V87-S90 WeakPolarHBondContact O-CB 3.23Å; V87-S90 PolarHBondContact O-N 3.18Å; V87-L91 WeakPolarHBondContact O-CB 3.48Å; V87-L91 PolarHBondContact O-N 3.25Å; V87-L166 HydrophobicContact CG1-CD1 3.64Å
88L94.4Very high92.1Very high1 Ų151.6 Ų51.61%0.00526%0.257CS..Hα-helixtrans-64.7-40.5176.7-65.6177.3000111.9L50 L84 S90 L91 S92 F151 L166 F362L50-L88 HydrophobicContact CD1-CD1 3.83Å; L84-L88 HydrophobicContact CD1-CD1 4.08Å; L84-L88 HydrophobicContact CD1-CG 4.06Å; L84-L88 HydrophobicContact CG-CD1 3.98Å; L84-L88 HydrophobicContact CG-CG 4.31Å; L84-L88 WeakPolarHBondContact O-CG 3.35Å; L84-L88 PolarHBondContact O-N 3.25Å; L88-S90 VanDerWaalsContact C-N 3.33Å; L88-S90 PolarHBondContact O-N 3.12Å; L88-L91 WeakPolarHBondContact O-CB 3.25Å; L88-L91 PolarHBondContact O-N 3.01Å; L88-S92 PolarHBondContact O-N 2.85Å; L88-F151 HydrophobicContact CD1-CE1 3.99Å; L88-F151 HydrophobicContact CD1-CZ 4.2Å; L88-F151 HydrophobicContact CD2-CE1 3.99Å; L88-F151 HydrophobicContact CD2-CZ 4.1Å; L88-L166 HydrophobicContact CD2-CB 4.13Å; L88-F362 HydrophobicContact CB-CE1 3.78Å; L88-F362 HydrophobicContact CB-CZ 4.37Å; L88-F362 HydrophobicContact CD1-CD1 4.36Å; L88-F362 HydrophobicContact CD1-CE1 3.93Å
89T94.3Very high92.6Very high19 Ų1950 Ų5012%0.11725%0.246CC..Hα-helixtrans-58.4-48.1172.8-59.30000110.2A85 L91 S92 T93A85-T89 VanDerWaalsContact O-CB 3.28Å; A85-T89 WeakPolarHBondContact O-CB 3.4Å; A85-T89 PolarHBondContact O-N 2.87Å; A85-T89 PolarHBondContact O-OG1 2.88Å; T89-L91 VanDerWaalsContact C-N 3.32Å; T89-L91 PolarHBondContact O-N 3.29Å; T89-S92 PolarHBondContact O-N 2.94Å; T89-S92 VanDerWaalsContact O-N 3.08Å; T89-S92 PolarHBondContact O-OG 3.02Å; T89-T93 PolarHBondContact O-N 3.15Å; T89-T93 VanDerWaalsContact O-N 3.11Å; T89-T93 PolarHBondContact O-OG1 3.09Å
90S94.9Very high93.2Very high24 Ų2448.3 Ų48.317%0.16824%0.24CC..Hα-helixtrans-59.6-41.9177.5-57.60000111.7A86 V87 L88 S92 T93 A94A86-S90 WeakPolarHBondContact O-CB 3.49Å; A86-S90 PolarHBondContact O-N 2.85Å; A86-S90 PolarHBondContact O-OG 3.43Å; V87-S90 WeakPolarHBondContact O-CB 3.23Å; V87-S90 PolarHBondContact O-N 3.18Å; L88-S90 VanDerWaalsContact C-N 3.33Å; L88-S90 PolarHBondContact O-N 3.12Å; S90-S92 PolarHBondContact O-N 2.85Å; S90-T93 PolarHBondContact O-N 2.9Å; S90-A94 WeakPolarHBondContact O-CB 3.3Å; S90-A94 PolarHBondContact O-N 3.02Å
91L95.1Very high93.5Very high1 Ų143 Ų431%0.00522%0.216CC..Hα-helixtrans-60.6-36.6177.1-169.665.9000111.4W64 V87 L88 T89 L114 V120 V168 R170 L223 L225W64-L91 HydrophobicContact CZ3-CB 4.37Å; W64-L91 HydrophobicContact CZ3-CD1 4.38Å; V87-L91 WeakPolarHBondContact O-CB 3.48Å; V87-L91 PolarHBondContact O-N 3.25Å; L88-L91 WeakPolarHBondContact O-CB 3.25Å; L88-L91 PolarHBondContact O-N 3.01Å; T89-L91 VanDerWaalsContact C-N 3.32Å; T89-L91 PolarHBondContact O-N 3.29Å; L91-L114 HydrophobicContact CD1-CD1 3.8Å; L91-V120 HydrophobicContact CD1-CG1 3.63Å; L91-V168 HydrophobicContact CB-CG1 3.81Å; L91-V168 HydrophobicContact CD2-CB 4.11Å; L91-V168 HydrophobicContact CD2-CG1 3.58Å; L91-V168 HydrophobicContact CG-CG1 3.55Å; L91-R170 PolarHBondContact O-NH1 3.26Å; L91-L223 HydrophobicContact CD1-CB 4.5Å; L91-L223 HydrophobicContact CD2-CB 4.44Å; L91-L223 HydrophobicContact CG-CB 4.2Å; L91-L223 VanDerWaalsContact O-CD1 3.26Å; L91-L223 WeakPolarHBondContact O-CD1 3.45Å; L91-L225 HydrophobicContact CD1-CD1 4.25Å
92S95.5Very high93.2Very high21 Ų2142.4 Ų42.415%0.14721%0.214CC..Hα-helixtrans-75.8-25.917975.50000114.3L88 T89 S90 R170L88-S92 PolarHBondContact O-N 2.85Å; T89-S92 PolarHBondContact O-N 2.94Å; T89-S92 VanDerWaalsContact O-N 3.08Å; T89-S92 PolarHBondContact O-OG 3.02Å; S90-S92 PolarHBondContact O-N 2.85Å; S92-R170 VanDerWaalsContact O-CD 3.24Å; S92-R170 WeakPolarHBondContact O-CD 3.36Å; S92-R170 WeakPolarHBondContact O-CG 3.29Å; S92-R170 PolarHBondContact O-NE 3.43Å
93T94.8Very high92Very high99 Ų9946 Ų4661%0.60722%0.216SC*.Hα-helixtrans-115.9-16.2-172.760.30000115.5T89 S90T89-T93 PolarHBondContact O-N 3.15Å; T89-T93 VanDerWaalsContact O-N 3.11Å; T89-T93 PolarHBondContact O-OG1 3.09Å; S90-T93 PolarHBondContact O-N 2.9Å
94A96.3Very high90.9Very high16 Ų1649.9 Ų49.913%0.13223%0.232CC..SBendtrans-58.7142.9-176.100000111.6W64 S90 L114 R170W64-A94 HydrophobicContact CH2-CB 4.15Å; W64-A94 HydrophobicContact CZ2-CB 3.8Å; S90-A94 WeakPolarHBondContact O-CB 3.3Å; S90-A94 PolarHBondContact O-N 3.02Å; A94-L114 HydrophobicContact CB-CB 4.22Å; A94-L114 HydrophobicContact CB-CD1 4.17Å; A94-R170 VanDerWaalsContact O-CZ 3.28Å; A94-R170 PolarHBondContact O-NH1 3.12Å; A94-R170 PolarHBondContact O-NH2 3.41Å
95R97.2Very high90.2Very high180 Ų18051.2 Ų51.268%0.67925%0.247SC*.PPolyproline II helixtrans-64.3138.1179.2-178178.7178.2177.6-0.7110L114 D115R95-L114 CarbonylContact O-C 3.6Å; R95-L114 VanDerWaalsContact O-CA 3.29Å; R95-L114 WeakPolarHBondContact O-CA 3.31Å; R95-D115 HydrophobicContact CB-CB 4.44Å; R95-D115 PolarHBondContact O-N 2.88Å
96I98.3Very high89.9Confident5 Ų554.6 Ų54.63%0.02627%0.268CS..EExtended strand (participates in β ladder)trans-86.2121.2171.6-60.2160.5000107.6L112 L114 V172 E177 I178 V181I96-L112 HydrophobicContact CD1-CD1 3.92Å; I96-L112 HydrophobicContact CG1-CD1 4.31Å; I96-L112 HydrophobicContact CG2-CB 4.23Å; I96-L112 HydrophobicContact CG2-CD2 4.37Å; I96-L114 HydrophobicContact CG1-CD2 3.78Å; I96-V172 HydrophobicContact CD1-CG1 3.87Å; I96-V172 HydrophobicContact CD1-CG2 4.4Å; I96-E177 HydrophobicContact CD1-CB 4.26Å; I96-I178 HydrophobicContact CD1-CD1 3.88Å; I96-I178 HydrophobicContact CG2-CD1 4.33Å; I96-V181 HydrophobicContact CG2-CG2 4.07Å
97E97.7Very high89.8Confident84 Ų8455.4 Ų55.439%0.39327%0.271SS..EExtended strand (participates in β ladder)trans-100.2-27.6-178.1-63.8-163.2138.400113.2V113 V181E97-V113 PolarHBondContact N-O 3.03Å; E97-V181 WeakPolarHBondContact O-CB 3.47Å; E97-V181 WeakPolarHBondContact O-CG1 3.07Å
98R97.4Very high89.7Confident179 Ų17955.8 Ų55.868%0.67527%0.273SS*.EExtended strand (participates in β ladder)trans-145.5145.9175.8-54.9-176.3-177.2-165.80.1110.7L112 V113 V181R98-L112 CarbonylContact O-C 3.5Å; R98-L112 WeakPolarHBondContact O-CA 3.49Å; R98-V113 HydrophobicContact CB-CB 3.97Å; R98-V113 HydrophobicContact CB-CG2 4.06Å; R98-V113 HydrophobicContact CG-CB 4.46Å; R98-V113 PolarHBondContact N-O 3.3Å; R98-V113 PolarHBondContact O-N 2.99Å; R98-V181 WeakPolarHBondContact CA-O 3.38Å
99A97.6Very high89.7Confident1 Ų158.1 Ų58.11%0.00828%0.283CS..EExtended strand (participates in β ladder)trans-133.5132.7173.400000110.6L112 I178 V181 A182 T183 L186A99-L112 HydrophobicContact CB-CD2 3.54Å; A99-I178 HydrophobicContact CB-CD1 4.23Å; A99-I178 HydrophobicContact CB-CG2 3.99Å; A99-V181 HydrophobicContact CB-CG2 4.31Å; A99-V181 PolarHBondContact N-O 3.33Å; A99-A182 HydrophobicContact CB-CB 4.26Å; A99-A182 CarbonylContact O-C 3.48Å; A99-A182 VanDerWaalsContact O-CA 3.22Å; A99-A182 WeakPolarHBondContact O-CA 3.42Å; A99-T183 PolarHBondContact O-N 3.06Å; A99-L186 HydrophobicContact CB-CD2 3.86Å
100D95.8Very high89.7Confident52 Ų5257.4 Ų57.428%0.27828%0.279SS..EExtended strand (participates in β ladder)trans-141.2166.8178.2-160.75.7000110.5A110 L111 T183D100-A110 CarbonylContact O-C 3.58Å; D100-A110 WeakPolarHBondContact O-CA 3.37Å; D100-L111 PolarHBondContact N-O 3.27Å; D100-L111 PolarHBondContact O-N 2.73Å; D100-T183 HydrophobicContact CB-CG2 3.81Å; D100-T183 VanDerWaalsContact CG-CG2 3.45Å; D100-T183 WeakPolarHBondContact OD1-CG2 3.5Å; D100-T183 PolarHBondContact OD1-OG1 2.81Å
101V89.3Confident89.8Confident11 Ų1158.3 Ų58.37%0.06728%0.281CS..EExtended strand (participates in β ladder)trans-67.4144.9169.2-62.80000110Y103 Q185 L186 K202V101-Y103 PolarHBondContact O-N 2.93Å; V101-Q185 HydrophobicContact CG1-CG 4.18Å; V101-Q185 VanDerWaalsContact CG2-CD 3.47Å; V101-Q185 HydrophobicContact CG2-CG 3.68Å; V101-Q185 VanDerWaalsContact CG2-NE2 3.3Å; V101-L186 HydrophobicContact CG1-CB 4.01Å; V101-L186 HydrophobicContact CG1-CD1 3.92Å; V101-K202 HydrophobicContact CB-CB 4.4Å; V101-K202 HydrophobicContact CG1-CB 4.26Å; V101-K202 HydrophobicContact CG1-CG 4.35Å; V101-K202 HydrophobicContact CG2-CB 4.41Å
102G76.2Confident89.9Confident10 Ų1058.3 Ų58.310%0.10328%0.281CS..  trans-60.1134.5173.900000112K104 K109G102-K104 PolarHBondContact O-N 3.46Å; G102-K109 PolarHBondContact N-O 3.21Å; G102-K109 VanDerWaalsContact N-O 3.09Å
103Y60.7Low90Very high180 Ų18058.5 Ų58.571%0.70628%0.282SS*.SBendtrans-73.6112.4174.3-174.9-99.4000110.3V101V101-Y103 PolarHBondContact O-N 2.93Å
104K67.2Low90.1Very high150 Ų15053.8 Ų53.865%0.65225%0.253SS*.SBendtrans60.7148176.4-60.1178.1177.71640114.2G102 K109G102-K104 PolarHBondContact O-N 3.46Å; K104-K109 VanDerWaalsContact O-CE 3.3Å; K104-K109 WeakPolarHBondContact O-CE 3.38Å; K104-K109 PolarHBondContact O-NZ 2.81Å
105G75.4Confident90Very high36 Ų3657.4 Ų57.437%0.37127%0.27SS..  trans140.4167179.100000112.5Y204G105-Y204 PolarHBondContact O-N 3.33Å; G105-Y204 VanDerWaalsContact O-N 3.08Å
106T82.7Confident89.6Confident71 Ų7151.8 Ų51.844%0.43627%0.268SS..SBendtrans-88.8-32.1-178.248.10000112.7C203 Y205T106-C203 PolarHBondContact O-SG 2.95Å; T106-Y205 HydrophobicContact CG2-CD2 4.39Å; T106-Y205 HydrophobicContact CG2-CE2 3.93Å; T106-Y205 WeakPolarHBondContact O-CB 3.47Å; T106-Y205 VanDerWaalsContact O-CD2 3.23Å; T106-Y205 WeakPolarHBondContact O-CD2 3.44Å; T106-Y205 PolarHBondContact O-N 2.86Å
107Q90.6Very high89.4Confident22 Ų2253.7 Ų53.710%0.10329%0.289CS..SBendtrans-111.8159.6-171.6-62.1-66.8-29.800112.6K109 D142Q107-K109 PolarHBondContact O-N 2.84Å; Q107-D142 HydrophobicContact CB-CB 4.3Å; Q107-D142 WeakPolarHBondContact CG-OD1 3.36Å
108L92.5Very high89.3Confident9 Ų951.5 Ų51.55%0.04728%0.279CS..  trans-67.3122.2-179.9177.355.9000111.3P124 F199 Y200 A212L108-P124 HydrophobicContact CD2-CG 4.01Å; L108-P124 HydrophobicContact CG-CG 4.11Å; L108-F199 HydrophobicContact CD1-CD2 4.09Å; L108-F199 HydrophobicContact CD1-CE2 3.73Å; L108-F199 HydrophobicContact CD2-CD2 4.49Å; L108-F199 HydrophobicContact CD2-CE2 4.2Å; L108-F199 HydrophobicContact CG-CE2 4.18Å; L108-Y200 VanDerWaalsContact CD1-O 3.27Å; L108-Y200 WeakPolarHBondContact CD1-O 3.47Å; L108-A212 HydrophobicContact CD2-CB 3.65Å
109K94.3Very high89.3Confident51 Ų5147 Ų4722%0.22226%0.264CS..  trans-151.3152.2172.163.2-172.9179.1-179.80110.1G102 K104 Q107 V121 F122 K123G102-K109 PolarHBondContact N-O 3.21Å; G102-K109 VanDerWaalsContact N-O 3.09Å; K104-K109 VanDerWaalsContact O-CE 3.3Å; K104-K109 WeakPolarHBondContact O-CE 3.38Å; K104-K109 PolarHBondContact O-NZ 2.81Å; Q107-K109 PolarHBondContact O-N 2.84Å; K109-V121 HydrophobicContact CB-CG1 4.05Å; K109-V121 HydrophobicContact CD-CG1 4.11Å; K109-V121 HydrophobicContact CG-CG1 4.5Å; K109-F122 WeakPolarHBondContact CA-O 3.47Å; K109-K123 HydrophobicContact CB-CG 4.29Å
110A95Very high89.3Confident3 Ų346.9 Ų46.93%0.02526%0.263CS..EExtended strand (participates in β ladder)trans-111.2146.5171.100000110D100 L112 F122D100-A110 CarbonylContact O-C 3.58Å; D100-A110 WeakPolarHBondContact O-CA 3.37Å; A110-L112 HydrophobicContact CB-CD2 4.23Å; A110-F122 HydrophobicContact CB-CB 4.31Å; A110-F122 HydrophobicContact CB-CD1 4.35Å; A110-F122 PolarHBondContact N-O 2.89Å; A110-F122 PolarHBondContact O-N 3.09Å
111L96.8Very high89.3Confident43 Ų4345.4 Ų45.423%0.22526%0.256CS..EExtended strand (participates in β ladder)trans-94.5119.6167.7176.466.4000107.2D100 K119 W226D100-L111 PolarHBondContact N-O 3.27Å; D100-L111 PolarHBondContact O-N 2.73Å; L111-K119 HydrophobicContact CD1-CB 4.23Å; L111-W226 HydrophobicContact CD1-CE3 4.38Å; L111-W226 HydrophobicContact CD1-CZ3 4.39Å
112L97.3Very high89.7Confident1 Ų145 Ų451%0.00525%0.253CS..EExtended strand (participates in β ladder)trans-110.5150.6173.7-47.7179.3000109.5I96 R98 A99 A110 K119 V120 F122 I178 L223I96-L112 HydrophobicContact CD1-CD1 3.92Å; I96-L112 HydrophobicContact CG1-CD1 4.31Å; I96-L112 HydrophobicContact CG2-CB 4.23Å; I96-L112 HydrophobicContact CG2-CD2 4.37Å; R98-L112 CarbonylContact O-C 3.5Å; R98-L112 WeakPolarHBondContact O-CA 3.49Å; A99-L112 HydrophobicContact CB-CD2 3.54Å; A110-L112 HydrophobicContact CB-CD2 4.23Å; L112-K119 WeakPolarHBondContact O-CA 3.07Å; L112-V120 HydrophobicContact CB-CG2 3.69Å; L112-V120 HydrophobicContact CG-CG2 4.48Å; L112-V120 PolarHBondContact N-O 3.45Å; L112-V120 PolarHBondContact O-N 3.16Å; L112-F122 HydrophobicContact CD1-CB 3.66Å; L112-F122 HydrophobicContact CD1-CD2 4.46Å; L112-F122 HydrophobicContact CD1-CG 4.1Å; L112-F122 HydrophobicContact CG-CB 3.91Å; L112-I178 HydrophobicContact CD1-CD1 4.21Å; L112-I178 HydrophobicContact CD2-CD1 3.74Å; L112-L223 HydrophobicContact CD1-CD2 3.85Å
113V97.7Very high90.7Very high26 Ų2644.7 Ų44.716%0.15825%0.249CC..EExtended strand (participates in β ladder)trans-116.3119.6169.4-1740000107.1E97 R98 Q118 K119E97-V113 PolarHBondContact N-O 3.03Å; R98-V113 HydrophobicContact CB-CB 3.97Å; R98-V113 HydrophobicContact CB-CG2 4.06Å; R98-V113 HydrophobicContact CG-CB 4.46Å; R98-V113 PolarHBondContact N-O 3.3Å; R98-V113 PolarHBondContact O-N 2.99Å; V113-Q118 WeakPolarHBondContact CA-O 3.15Å; V113-K119 HydrophobicContact CG2-CG 4.47Å
114L97.3Very high92.4Very high0 Ų036.3 Ų36.30%022%0.217CC..EExtended strand (participates in β ladder)trans-85.7164.9176.1-55.9-178.6000110.3W64 L91 A94 R95 I96 G116 G117 Q118 V120W64-L114 HydrophobicContact CH2-CD1 4.15Å; W64-L114 HydrophobicContact CZ2-CB 4.47Å; W64-L114 HydrophobicContact CZ2-CD1 4.19Å; L91-L114 HydrophobicContact CD1-CD1 3.8Å; A94-L114 HydrophobicContact CB-CB 4.22Å; A94-L114 HydrophobicContact CB-CD1 4.17Å; R95-L114 CarbonylContact O-C 3.6Å; R95-L114 VanDerWaalsContact O-CA 3.29Å; R95-L114 WeakPolarHBondContact O-CA 3.31Å; I96-L114 HydrophobicContact CG1-CD2 3.78Å; L114-G116 PolarHBondContact O-N 3.41Å; L114-G117 PolarHBondContact O-N 3Å; L114-Q118 PolarHBondContact N-O 2.86Å; L114-Q118 PolarHBondContact O-N 3.16Å; L114-V120 HydrophobicContact CD1-CG1 3.61Å; L114-V120 HydrophobicContact CD1-CG2 4.2Å; L114-V120 HydrophobicContact CD2-CG2 4.19Å; L114-V120 HydrophobicContact CG-CG1 4.02Å; L114-V120 HydrophobicContact CG-CG2 3.96Å
115D93.1Very high93.9Very high92 Ų9232 Ų3249%0.49220%0.198SC..THydrogen-bonded Turntrans-47.9138.3169.7-172.12.6000111.1W64 R95 G117W64-D115 PolarHBondContact NE1-O 3.09Å; R95-D115 HydrophobicContact CB-CB 4.44Å; R95-D115 PolarHBondContact O-N 2.88Å; D115-G117 VanDerWaalsContact C-N 3.35Å
116G89.6Confident94.9Very high62 Ų6232.5 Ų32.564%0.63919%0.189SC*.THydrogen-bonded Turntrans81.110.8-168.700000114.2L114 Q118L114-G116 PolarHBondContact O-N 3.41Å; G116-Q118 VanDerWaalsContact C-N 3.26Å; G116-Q118 PolarHBondContact O-N 2.97Å
117G93.2Very high95.5Very high45 Ų4530.9 Ų30.946%0.46418%0.175SC..THydrogen-bonded Turntrans74.810175.400000115L114 D115 K119L114-G117 PolarHBondContact O-N 3Å; D115-G117 VanDerWaalsContact C-N 3.35Å; G117-K119 PolarHBondContact O-N 3.14Å
118Q96.3Very high95.8Very high38 Ų3835.2 Ų35.218%0.17820%0.199CC..EExtended strand (participates in β ladder)trans-73.6125.2-176.8178.757.552.800111.4W64 V113 L114 G116 L225 W226W64-Q118 HydrophobicContact CB-CB 4.16Å; W64-Q118 HydrophobicContact CB-CG 4.08Å; W64-Q118 VanDerWaalsContact CD1-CB 3.48Å; W64-Q118 HydrophobicContact CD2-CB 3.93Å; W64-Q118 HydrophobicContact CD2-CG 3.87Å; W64-Q118 HydrophobicContact CE3-CG 4.28Å; W64-Q118 HydrophobicContact CG-CB 3.59Å; W64-Q118 HydrophobicContact CG-CG 3.77Å; V113-Q118 WeakPolarHBondContact CA-O 3.15Å; L114-Q118 PolarHBondContact N-O 2.86Å; L114-Q118 PolarHBondContact O-N 3.16Å; G116-Q118 VanDerWaalsContact C-N 3.26Å; G116-Q118 PolarHBondContact O-N 2.97Å; Q118-L225 HydrophobicContact CG-CD1 3.47Å; Q118-L225 VanDerWaalsContact CG-CD1 3.47Å; Q118-W226 PolarHBondContact NE2-O 2.62Å
119K96.8Very high95.9Very high83 Ų8336.6 Ų36.636%0.36120%0.203SC..EExtended strand (participates in β ladder)trans-80142176.8-64.4174.9-168.7160.80110.8L111 L112 V113 G117 W226L111-K119 HydrophobicContact CD1-CB 4.23Å; L112-K119 WeakPolarHBondContact O-CA 3.07Å; V113-K119 HydrophobicContact CG2-CG 4.47Å; G117-K119 PolarHBondContact O-N 3.14Å; K119-W226 HydrophobicContact CB-CB 3.73Å; K119-W226 HydrophobicContact CB-CD2 4.48Å; K119-W226 HydrophobicContact CB-CG 4.02Å; K119-W226 WeakPolarHBondContact O-CB 3.4Å; K119-W226 PolarHBondContact O-N 3.23Å; K119-W226 VanDerWaalsContact O-N 3.09Å
120V96.9Very high95.9Very high0 Ų040.4 Ų40.40%023%0.226CC..EExtended strand (participates in β ladder)trans-142.2149173.6-57.70000110.4L91 L112 L114 L223 T224 L225L91-V120 HydrophobicContact CD1-CG1 3.63Å; L112-V120 HydrophobicContact CB-CG2 3.69Å; L112-V120 HydrophobicContact CG-CG2 4.48Å; L112-V120 PolarHBondContact N-O 3.45Å; L112-V120 PolarHBondContact O-N 3.16Å; L114-V120 HydrophobicContact CD1-CG1 3.61Å; L114-V120 HydrophobicContact CD1-CG2 4.2Å; L114-V120 HydrophobicContact CD2-CG2 4.19Å; L114-V120 HydrophobicContact CG-CG1 4.02Å; L114-V120 HydrophobicContact CG-CG2 3.96Å; V120-L223 HydrophobicContact CB-CD2 4.46Å; V120-L223 HydrophobicContact CG2-CD2 3.79Å; V120-T224 CarbonylContact C-O 3.53Å; V120-T224 VanDerWaalsContact CA-O 3.24Å; V120-T224 WeakPolarHBondContact CA-O 3.26Å; V120-T224 WeakPolarHBondContact CB-O 3.41Å; V120-L225 HydrophobicContact CG1-CD1 4.2Å
121V96.5Very high96Very high21 Ų2145.9 Ų45.913%0.12725%0.247CC..EExtended strand (participates in β ladder)trans-93.8125.7171.3-178.70000108.9K109 K123 L223 T224 W226K109-V121 HydrophobicContact CB-CG1 4.05Å; K109-V121 HydrophobicContact CD-CG1 4.11Å; K109-V121 HydrophobicContact CG-CG1 4.5Å; V121-K123 HydrophobicContact CG1-CG 4.29Å; V121-L223 CarbonylContact O-C 3.31Å; V121-L223 WeakPolarHBondContact O-CA 3.25Å; V121-T224 PolarHBondContact N-O 2.87Å; V121-T224 PolarHBondContact O-N 3.39Å; V121-W226 HydrophobicContact CG2-CE3 3.62Å; V121-W226 HydrophobicContact CG2-CZ3 3.48Å; V121-W226 VanDerWaalsContact CG2-CZ3 3.48Å
122F97.4Very high96Very high2 Ų246.5 Ų46.51%0.00925%0.253CS..EExtended strand (participates in β ladder)trans-102.2119.1171.7179.5-107.2000110.6K109 A110 L112 P124 V172 F199 M219 S222 L223K109-F122 WeakPolarHBondContact CA-O 3.47Å; A110-F122 HydrophobicContact CB-CB 4.31Å; A110-F122 HydrophobicContact CB-CD1 4.35Å; A110-F122 PolarHBondContact N-O 2.89Å; A110-F122 PolarHBondContact O-N 3.09Å; L112-F122 HydrophobicContact CD1-CB 3.66Å; L112-F122 HydrophobicContact CD1-CD2 4.46Å; L112-F122 HydrophobicContact CD1-CG 4.1Å; L112-F122 HydrophobicContact CG-CB 3.91Å; F122-P124 HydrophobicContact CE1-CB 3.9Å; F122-P124 HydrophobicContact CZ-CB 4.38Å; F122-V172 HydrophobicContact CE2-CG2 3.95Å; F122-V172 HydrophobicContact CZ-CG2 4.36Å; F122-F199 HydrophobicContact CE1-CZ 4.44Å; F122-M219 HydrophobicContact CE1-CG 4.47Å; F122-M219 HydrophobicContact CE1-SD 3.93Å; F122-M219 HydrophobicContact CZ-CG 4.13Å; F122-M219 HydrophobicContact CZ-SD 4.19Å; F122-S222 WeakPolarHBondContact CA-O 3.23Å; F122-L223 HydrophobicContact CB-CD2 3.88Å; F122-L223 HydrophobicContact CD2-CD2 3.71Å; F122-L223 HydrophobicContact CD2-CG 4.34Å; F122-L223 HydrophobicContact CG-CD2 4.26Å
123K97.3Very high95.9Very high4 Ų447.3 Ų47.32%0.01726%0.257CS..EExtended strand (participates in β ladder)trans-107.1116.9169.6-62.6-169.2-177.8-174.90109.1K109 V121 D142 H144 E147 G221 S222 D311 A313K109-K123 HydrophobicContact CB-CG 4.29Å; V121-K123 HydrophobicContact CG1-CG 4.29Å; K123-D142 HydrophobicContact CD-CB 4.4Å; K123-D142 IonicContact NZ-OD2 3.9Å; K123-D142 PolarHBondContact NZ-OD2 2.98Å; K123-H144 VanDerWaalsContact O-CB 3.23Å; K123-H144 WeakPolarHBondContact O-CB 3.33Å; K123-E147 HydrophobicContact CD-CG 4.15Å; K123-E147 WeakPolarHBondContact CE-OE1 3.35Å; K123-E147 IonicContact NZ-OE1 3.72Å; K123-E147 PolarHBondContact NZ-OE1 2.84Å; K123-G221 CarbonylContact O-C 3.57Å; K123-G221 VanDerWaalsContact O-CA 3.23Å; K123-G221 WeakPolarHBondContact O-CA 3.4Å; K123-S222 PolarHBondContact N-O 3.41Å; K123-S222 PolarHBondContact O-N 2.86Å; K123-D311 IonicContact NZ-OD1 3.64Å; K123-D311 PolarHBondContact NZ-OD1 2.82Å; K123-A313 HydrophobicContact CD-CB 4.01Å
124P97.3Very high95.7Very high3 Ų353.8 Ų53.82%0.01929%0.286CS..EExtended strand (participates in β ladder)trans-76.9156.3-176.432.1-36.1000112.1L108 F122 R126 F199 A212 M219L108-P124 HydrophobicContact CD2-CG 4.01Å; L108-P124 HydrophobicContact CG-CG 4.11Å; F122-P124 HydrophobicContact CE1-CB 3.9Å; F122-P124 HydrophobicContact CZ-CB 4.38Å; P124-R126 PolarHBondContact O-N 2.98Å; P124-F199 HydrophobicContact CB-CZ 4.36Å; P124-F199 HydrophobicContact CG-CZ 4.16Å; P124-A212 HydrophobicContact CB-CB 3.81Å; P124-A212 HydrophobicContact CG-CB 3.61Å; P124-M219 HydrophobicContact CB-CE 4.37Å; P124-M219 HydrophobicContact CB-CG 4.28Å; P124-M219 HydrophobicContact CB-SD 3.43Å; P124-M219 WeakPolarHBondContact CB-SD 3.38Å
125K97.6Very high95.4Very high60 Ų6057.1 Ų57.126%0.26132%0.321SS..  trans-59.7129.5170.2177.5177.7174.6-174.60111Y127 N128 H144 E220K125-Y127 WeakPolarHBondContact CE-O 3.3Å; K125-Y127 WeakPolarHBondContact CG-O 3.34Å; K125-N128 PolarHBondContact NZ-OD1 2.93Å; K125-H144 WeakPolarHBondContact CA-ND1 3.48Å; K125-H144 VanDerWaalsContact CB-CE1 3.49Å; K125-H144 WeakPolarHBondContact CB-CE1 3.23Å; K125-E220 HydrophobicContact CB-CB 4.17Å; K125-E220 VanDerWaalsContact CB-O 3.25Å; K125-E220 WeakPolarHBondContact CB-O 3.18Å; K125-E220 HydrophobicContact CD-CB 4.17Å; K125-E220 PolarHBondContact N-O 2.92Å; K125-E220 IonicContact NZ-OE2 3.75Å
126R96.3Very high95.2Very high46 Ų4658.2 Ų58.217%0.17432%0.323CS..  trans-115.9-25.6176.7-59-57.5-57.5-74.14.1114P124 Y141 E210P124-R126 PolarHBondContact O-N 2.98Å; R126-Y141 HydrophobicContact CB-CD2 4.05Å; R126-Y141 HydrophobicContact CB-CG 4.34Å; R126-Y141 HydrophobicContact CG-CG 4.4Å; R126-Y141 VanDerWaalsContact NH2-CE2 3.32Å; R126-Y141 VanDerWaalsContact NH2-CZ 3.26Å; R126-E210 PolarHBondContact NH2-O 3.34Å
127Y96.5Very high95.1Very high38 Ų3857.2 Ų57.215%0.14931%0.305CS..SBendtrans-135.4160.1-177.1-59.5-69.2000111.2K125 Y131 G140 Y141 R143K125-Y127 WeakPolarHBondContact CE-O 3.3Å; K125-Y127 WeakPolarHBondContact CG-O 3.34Å; Y127-Y131 AromaticContact CD1-CD1 3.38Å; Y127-Y131 HydrophobicContact CD1-CD1 3.38Å; Y127-Y131 HydrophobicContact CD1-CD2 4.21Å; Y127-Y131 AromaticContact CD1-CE1 3.44Å; Y127-Y131 HydrophobicContact CD1-CE1 3.44Å; Y127-Y131 VanDerWaalsContact CD1-CE1 3.44Å; Y127-Y131 HydrophobicContact CD1-CE2 4.27Å; Y127-Y131 AromaticContact CD1-CG 3.78Å; Y127-Y131 HydrophobicContact CD1-CG 3.78Å; Y127-Y131 AromaticContact CD1-CZ 3.91Å; Y127-Y131 HydrophobicContact CD2-CD1 4.29Å; Y127-Y131 AromaticContact CE1-CD1 3.82Å; Y127-Y131 HydrophobicContact CE1-CD1 3.82Å; Y127-Y131 AromaticContact CE1-CE1 3.35Å; Y127-Y131 HydrophobicContact CE1-CE1 3.35Å; Y127-Y131 HydrophobicContact CE1-CE2 4.44Å; Y127-Y131 AromaticContact CE1-CZ 3.72Å; Y127-Y131 HydrophobicContact CE2-CE1 4.49Å; Y127-Y131 AromaticContact CG-CD1 3.64Å; Y127-Y131 HydrophobicContact CG-CD1 3.64Å; Y127-Y131 HydrophobicContact CG-CE1 4.07Å; Y127-Y131 HydrophobicContact CG-CG 4.12Å; Y127-Y131 AromaticContact CZ-CE1 3.9Å; Y127-G140 WeakPolarHBondContact OH-CA 3.36Å; Y127-Y141 AromaticContact CE1-CD2 3.94Å; Y127-Y141 HydrophobicContact CE1-CD2 3.94Å; Y127-Y141 HydrophobicContact CE1-CE2 4.35Å; Y127-Y141 AromaticContact CE2-CD2 3.75Å; Y127-Y141 HydrophobicContact CE2-CD2 3.75Å; Y127-Y141 HydrophobicContact CE2-CG 4.17Å; Y127-Y141 AromaticContact CZ-CD2 3.31Å; Y127-Y141 WeakPolarHBondContact OH-CD2 3.47Å; Y127-Y141 PolarHBondContact OH-N 3.18Å; Y127-R143 HydrophobicContact CD2-CG 3.88Å; Y127-R143 HydrophobicContact CE2-CG 4.44Å
128N95.8Very high94.9Very high113 Ų11358 Ų5860%0.60429%0.294SS*.  trans-75.2160.1167.7-70.4-31.2000110.8K125 D130 Y131K125-N128 PolarHBondContact NZ-OD1 2.93Å; N128-D130 PolarHBondContact O-N 3.29Å; N128-Y131 VanDerWaalsContact O-CB 3.29Å; N128-Y131 WeakPolarHBondContact O-CB 3.32Å; N128-Y131 PolarHBondContact O-N 2.78Å; N128-Y131 VanDerWaalsContact O-N 3.13Å
129R95.3Very high94.6Very high38 Ų3857.5 Ų57.514%0.14330%0.297CS..THydrogen-bonded Turntrans-61.3-31.3-176.1-67.2-63.3-167.2-84.1-7.5113.7H144 E220 I365 P367 V368R129-H144 PolarHBondContact NH1-CE1 3.39Å; R129-H144 VanDerWaalsContact NH1-CE1 3.25Å; R129-H144 PolarHBondContact NH1-NE2 3.38Å; R129-E220 IonicContact CZ-OE1 3.39Å; R129-E220 IonicContact NH1-OE1 3.65Å; R129-E220 PolarHBondContact NH1-OE1 2.94Å; R129-E220 IonicContact NH2-OE1 2.72Å; R129-E220 PolarHBondContact NH2-OE1 3.01Å; R129-I365 PolarHBondContact NH2-O 3.35Å; R129-I365 VanDerWaalsContact NH2-O 3.12Å; R129-P367 PolarHBondContact NE-O 2.99Å; R129-P367 PolarHBondContact NH2-O 2.9Å; R129-V368 VanDerWaalsContact CD-O 3.25Å; R129-V368 WeakPolarHBondContact CD-O 3.41Å; R129-V368 PolarHBondContact NE-O 3.14Å; R129-V368 VanDerWaalsContact NE-O 3.09Å
130D94.8Very high94.4Very high131 Ų13154.9 Ų54.970%0.70129%0.293SS*.THydrogen-bonded Turntrans-91.82-178.8-52.2-48.9000113.1N128 V132N128-D130 PolarHBondContact O-N 3.29Å; D130-V132 PolarHBondContact O-N 3.04Å
131Y96.6Very high94.3Very high117 Ų11757.5 Ų57.546%0.45930%0.304SS..PPolyproline II helixtrans-70.9125.6-179.9-175.3-94.6000110.4Y127 N128 V133Y127-Y131 AromaticContact CD1-CD1 3.38Å; Y127-Y131 HydrophobicContact CD1-CD1 3.38Å; Y127-Y131 HydrophobicContact CD1-CD2 4.21Å; Y127-Y131 AromaticContact CD1-CE1 3.44Å; Y127-Y131 HydrophobicContact CD1-CE1 3.44Å; Y127-Y131 VanDerWaalsContact CD1-CE1 3.44Å; Y127-Y131 HydrophobicContact CD1-CE2 4.27Å; Y127-Y131 AromaticContact CD1-CG 3.78Å; Y127-Y131 HydrophobicContact CD1-CG 3.78Å; Y127-Y131 AromaticContact CD1-CZ 3.91Å; Y127-Y131 HydrophobicContact CD2-CD1 4.29Å; Y127-Y131 AromaticContact CE1-CD1 3.82Å; Y127-Y131 HydrophobicContact CE1-CD1 3.82Å; Y127-Y131 AromaticContact CE1-CE1 3.35Å; Y127-Y131 HydrophobicContact CE1-CE1 3.35Å; Y127-Y131 HydrophobicContact CE1-CE2 4.44Å; Y127-Y131 AromaticContact CE1-CZ 3.72Å; Y127-Y131 HydrophobicContact CE2-CE1 4.49Å; Y127-Y131 AromaticContact CG-CD1 3.64Å; Y127-Y131 HydrophobicContact CG-CD1 3.64Å; Y127-Y131 HydrophobicContact CG-CE1 4.07Å; Y127-Y131 HydrophobicContact CG-CG 4.12Å; Y127-Y131 AromaticContact CZ-CE1 3.9Å; N128-Y131 VanDerWaalsContact O-CB 3.29Å; N128-Y131 WeakPolarHBondContact O-CB 3.32Å; N128-Y131 PolarHBondContact O-N 2.78Å; N128-Y131 VanDerWaalsContact O-N 3.13Å; Y131-V133 HydrophobicContact CD1-CG2 4.09Å; Y131-V133 HydrophobicContact CE1-CG2 3.96Å
132V96.7Very high94.3Very high57 Ų5757.4 Ų57.435%0.34530%0.303SS..PPolyproline II helixtrans-98.2126.9176.31800000109.2D130 N318D130-V132 PolarHBondContact O-N 3.04Å; V132-N318 HydrophobicContact CG1-CB 4.16Å; V132-N318 WeakPolarHBondContact CG1-ND2 3.41Å
133V95.8Very high94.3Very high17 Ų1758.1 Ų58.110%0.10331%0.305CS..PPolyproline II helixtrans-83.3123.4172.9-176.60000109.5Y131 A139 G317 N318Y131-V133 HydrophobicContact CD1-CG2 4.09Å; Y131-V133 HydrophobicContact CE1-CG2 3.96Å; V133-A139 HydrophobicContact CG1-CB 4.15Å; V133-G317 PolarHBondContact N-O 2.8Å; V133-N318 PolarHBondContact O-ND2 2.76Å
134E92.5Very high94.3Very high162 Ų16258 Ų5876%0.75730%0.304SS*.  trans-105.4164.5176.9-60.4-175.1161.900111.1
135G90.4Very high94.3Very high71 Ų7158.5 Ų58.573%0.73231%0.307SS*.SBendtrans93.7-144.3179.600000113.1
136E89.8Confident94.3Very high114 Ų11455.6 Ų55.653%0.53330%0.295SS..SBendtrans-61.3148.5-177.4-66.9-61.3146.800112.3Y138 A139E136-Y138 HydrophobicContact CB-CD1 4.24Å; E136-Y138 HydrophobicContact CB-CE1 3.91Å; E136-Y138 HydrophobicContact CB-CE2 4.19Å; E136-Y138 HydrophobicContact CG-CE1 4.36Å; E136-Y138 PolarHBondContact O-N 2.8Å; E136-A139 HydrophobicContact CB-CB 4.4Å; E136-A139 WeakPolarHBondContact O-CB 3.39Å; E136-A139 PolarHBondContact O-N 2.93Å
137P87.8Confident94.3Very high41 Ų4153.7 Ų53.727%0.26629%0.288SS..THydrogen-bonded Turntrans-56.8-19.4-178.8-28.636.4000115.9A290 E323P137-A290 HydrophobicContact CB-CB 3.39Å; P137-E323 HydrophobicContact CB-CG 4.25Å; P137-E323 HydrophobicContact CG-CG 4.35Å; P137-E323 WeakPolarHBondContact CG-OE2 3.41Å
138Y88.6Confident94.3Very high62 Ų6251.9 Ų51.924%0.24328%0.281CS..THydrogen-bonded Turntrans-106.28.4179.754.6-94.3000113.8E136 Y244 K314E136-Y138 HydrophobicContact CB-CD1 4.24Å; E136-Y138 HydrophobicContact CB-CE1 3.91Å; E136-Y138 HydrophobicContact CB-CE2 4.19Å; E136-Y138 HydrophobicContact CG-CE1 4.36Å; E136-Y138 PolarHBondContact O-N 2.8Å; Y138-Y244 HydrophobicContact CD1-CD1 4.07Å; Y138-Y244 AromaticContact CD1-CE1 3.92Å; Y138-Y244 HydrophobicContact CD1-CE1 3.92Å; Y138-Y244 AromaticContact CD2-CD1 3.84Å; Y138-Y244 HydrophobicContact CD2-CD1 3.84Å; Y138-Y244 AromaticContact CD2-CE1 3.94Å; Y138-Y244 HydrophobicContact CD2-CE1 3.94Å; Y138-Y244 HydrophobicContact CE1-CD1 4.02Å; Y138-Y244 HydrophobicContact CE1-CE1 4.33Å; Y138-Y244 AromaticContact CE2-CD1 3.79Å; Y138-Y244 HydrophobicContact CE2-CD1 3.79Å; Y138-Y244 HydrophobicContact CE2-CE1 4.35Å; Y138-Y244 AromaticContact CG-CD1 3.98Å; Y138-Y244 HydrophobicContact CG-CD1 3.98Å; Y138-Y244 AromaticContact CG-CE1 3.71Å; Y138-Y244 HydrophobicContact CG-CE1 3.71Å; Y138-Y244 AromaticContact CZ-CD1 3.87Å; Y138-K314 PolarHBondContact O-NZ 3.27Å
139A90.9Very high94.3Very high28 Ų2846.5 Ų46.523%0.23125%0.252CS..  trans-69.8168.2-17600000113.9V133 E136V133-A139 HydrophobicContact CG1-CB 4.15Å; E136-A139 HydrophobicContact CB-CB 4.4Å; E136-A139 WeakPolarHBondContact O-CB 3.39Å; E136-A139 PolarHBondContact O-N 2.93Å
140G92.8Very high94.4Very high28 Ų2844.7 Ų44.729%0.28925%0.245SC..SBendtrans79.6176.7176.500000114.7Y127 K314Y127-G140 WeakPolarHBondContact OH-CA 3.36Å; G140-K314 PolarHBondContact O-NZ 3.19Å
141Y94.7Very high94.3Very high54 Ų5438.5 Ų38.521%0.21221%0.212CC..  trans-78.1162.6175.1-52.7-60000112.6R126 Y127 R143 E210R126-Y141 HydrophobicContact CB-CD2 4.05Å; R126-Y141 HydrophobicContact CB-CG 4.34Å; R126-Y141 HydrophobicContact CG-CG 4.4Å; R126-Y141 VanDerWaalsContact NH2-CE2 3.32Å; R126-Y141 VanDerWaalsContact NH2-CZ 3.26Å; Y127-Y141 AromaticContact CE1-CD2 3.94Å; Y127-Y141 HydrophobicContact CE1-CD2 3.94Å; Y127-Y141 HydrophobicContact CE1-CE2 4.35Å; Y127-Y141 AromaticContact CE2-CD2 3.75Å; Y127-Y141 HydrophobicContact CE2-CD2 3.75Å; Y127-Y141 HydrophobicContact CE2-CG 4.17Å; Y127-Y141 AromaticContact CZ-CD2 3.31Å; Y127-Y141 WeakPolarHBondContact OH-CD2 3.47Å; Y127-Y141 PolarHBondContact OH-N 3.18Å; Y141-R143 PolarHBondContact O-N 3.26Å; Y141-E210 WeakPolarHBondContact OH-CG 3.02Å; Y141-E210 PolarHBondContact OH-OE1 2.86Å
142D95.8Very high94.1Very high20 Ų2033.1 Ų33.111%0.10719%0.191CC..  trans-56.1132.8164.4-85.818.7000110.7Q107 K123 A313 K314Q107-D142 HydrophobicContact CB-CB 4.3Å; Q107-D142 WeakPolarHBondContact CG-OD1 3.36Å; K123-D142 HydrophobicContact CD-CB 4.4Å; K123-D142 IonicContact NZ-OD2 3.9Å; K123-D142 PolarHBondContact NZ-OD2 2.98Å; D142-A313 HydrophobicContact CB-CB 3.51Å; D142-A313 WeakPolarHBondContact OD2-CB 3.44Å; D142-K314 WeakPolarHBondContact OD1-CE 3.46Å
143R96.9Very high93.8Very high16 Ų1630.4 Ų30.46%0.0617%0.174CC..  trans-105.2118.1178.5-70.9166.4-66-98.47.2109.2Y127 Y141 N145 A146 A313 K314 S315Y127-R143 HydrophobicContact CD2-CG 3.88Å; Y127-R143 HydrophobicContact CE2-CG 4.44Å; Y141-R143 PolarHBondContact O-N 3.26Å; R143-N145 PolarHBondContact O-N 3.01Å; R143-A146 HydrophobicContact CB-CB 3.77Å; R143-A146 VanDerWaalsContact O-CB 3.29Å; R143-A146 WeakPolarHBondContact O-CB 3.23Å; R143-A146 PolarHBondContact O-N 3.27Å; R143-A313 PolarHBondContact N-O 3.18Å; R143-K314 PolarHBondContact NH2-O 2.77Å; R143-S315 VanDerWaalsContact CZ-O 3.22Å; R143-S315 PolarHBondContact NE-O 2.9Å; R143-S315 PolarHBondContact NH2-O 3.08Å
144H97.4Very high93.2Very high1 Ų129.6 Ų29.61%0.00517%0.17CC..Hα-helixtrans-65.9-38.6-177.571.3-63.2000112.4K123 K125 R129 A146 E147 V148 E220 S222K123-H144 VanDerWaalsContact O-CB 3.23Å; K123-H144 WeakPolarHBondContact O-CB 3.33Å; K125-H144 WeakPolarHBondContact CA-ND1 3.48Å; K125-H144 VanDerWaalsContact CB-CE1 3.49Å; K125-H144 WeakPolarHBondContact CB-CE1 3.23Å; R129-H144 PolarHBondContact NH1-CE1 3.39Å; R129-H144 VanDerWaalsContact NH1-CE1 3.25Å; R129-H144 PolarHBondContact NH1-NE2 3.38Å; H144-A146 PolarHBondContact O-N 2.92Å; H144-E147 PolarHBondContact O-N 2.9Å; H144-V148 PolarHBondContact O-N 2.9Å; H144-E220 IonicContact CD2-OE1 3.21Å; H144-E220 IonicContact CE1-OE1 2.68Å; H144-E220 PolarHBondContact CE1-OE1 3.38Å; H144-E220 IonicContact NE2-OE1 3.54Å; H144-E220 PolarHBondContact NE2-OE1 3.25Å; H144-S222 WeakPolarHBondContact CB-OG 3.28Å; H144-S222 WeakPolarHBondContact O-CB 3.45Å
145N97.6Very high92.4Very high14 Ų1423.3 Ų23.38%0.07514%0.141CC..Hα-helixtrans-65.2-26.117767.5-53.5000112.2R143 A149 V368R143-N145 PolarHBondContact O-N 3.01Å; N145-A149 VanDerWaalsContact O-CB 3.3Å; N145-A149 WeakPolarHBondContact O-CB 3.27Å; N145-A149 PolarHBondContact O-N 3.44Å; N145-V368 HydrophobicContact CB-CG1 3.96Å; N145-V368 WeakPolarHBondContact CB-O 3.25Å; N145-V368 PolarHBondContact ND2-O 3.47Å; N145-V368 VanDerWaalsContact O-CG1 3.29Å; N145-V368 WeakPolarHBondContact O-CG1 3.38Å
146A97.4Very high90.8Very high0 Ų020 Ų200%011%0.106CC..Hα-helixtrans-70.5-35.7175.700000112.3R143 H144 A150 S315 F316R143-A146 HydrophobicContact CB-CB 3.77Å; R143-A146 VanDerWaalsContact O-CB 3.29Å; R143-A146 WeakPolarHBondContact O-CB 3.23Å; R143-A146 PolarHBondContact O-N 3.27Å; H144-A146 PolarHBondContact O-N 2.92Å; A146-A150 WeakPolarHBondContact O-CB 3.47Å; A146-A150 PolarHBondContact O-N 3.49Å; A146-S315 WeakPolarHBondContact CB-O 3.38Å; A146-S315 WeakPolarHBondContact CB-OG 3.3Å; A146-F316 HydrophobicContact CB-CB 4.36Å; A146-F316 HydrophobicContact CB-CD2 3.93Å
147E96.8Very high89.2Confident6 Ų617 Ų173%0.0289%0.09CC..Hα-helixtrans-64.6-45.7172.5-66.1-72.6-172.200111.5K123 H144 A149 A150 F151 V167 N312 A313K123-E147 HydrophobicContact CD-CG 4.15Å; K123-E147 WeakPolarHBondContact CE-OE1 3.35Å; K123-E147 IonicContact NZ-OE1 3.72Å; K123-E147 PolarHBondContact NZ-OE1 2.84Å; H144-E147 PolarHBondContact O-N 2.9Å; E147-A149 PolarHBondContact O-N 2.94Å; E147-A150 PolarHBondContact O-N 2.69Å; E147-F151 PolarHBondContact O-N 2.72Å; E147-V167 HydrophobicContact CB-CG1 3.98Å; E147-N312 PolarHBondContact OE1-N 2.86Å; E147-N312 VanDerWaalsContact OE1-N 3.13Å; E147-N312 WeakPolarHBondContact OE2-CB 3.33Å; E147-N312 PolarHBondContact OE2-N 3.25Å; E147-A313 HydrophobicContact CG-CB 3.74Å; E147-A313 VanDerWaalsContact OE1-CB 3.25Å; E147-A313 WeakPolarHBondContact OE1-CB 3.43Å; E147-A313 PolarHBondContact OE1-N 2.92Å
148V96.8Very high87.4Confident0 Ų015.5 Ų15.50%08%0.08CC..Hα-helixtrans-59.6-49.1177176.50000110H144 A150 F151 H152 V167 L360 D363 I365 V368H144-V148 PolarHBondContact O-N 2.9Å; V148-A150 PolarHBondContact O-N 3.45Å; V148-F151 PolarHBondContact O-N 2.94Å; V148-H152 PolarHBondContact O-CD2 2.78Å; V148-H152 VanDerWaalsContact O-CD2 3.27Å; V148-H152 PolarHBondContact O-N 2.86Å; V148-V167 HydrophobicContact CB-CG1 4.45Å; V148-V167 HydrophobicContact CG2-CG1 3.84Å; V148-L360 HydrophobicContact CG1-CD2 4.41Å; V148-D363 HydrophobicContact CG1-CB 4.26Å; V148-D363 VanDerWaalsContact CG1-OD2 3.22Å; V148-D363 WeakPolarHBondContact CG1-OD2 3.44Å; V148-I365 HydrophobicContact CG2-CD1 4.27Å; V148-V368 HydrophobicContact CB-CG1 3.9Å; V148-V368 HydrophobicContact CG1-CG1 3.79Å; V148-V368 HydrophobicContact CG1-CG2 4.04Å
149A96.1Very high86.6Confident0 Ų012.7 Ų12.70%07%0.069CC..Hα-helixtrans-64.2-39.617900000113.2N145 E147 H152 L153 F316 M356 L360 V368 L369N145-A149 VanDerWaalsContact O-CB 3.3Å; N145-A149 WeakPolarHBondContact O-CB 3.27Å; N145-A149 PolarHBondContact O-N 3.44Å; E147-A149 PolarHBondContact O-N 2.94Å; A149-H152 PolarHBondContact O-N 2.88Å; A149-L153 VanDerWaalsContact O-CB 3.31Å; A149-L153 WeakPolarHBondContact O-CB 3.47Å; A149-L153 PolarHBondContact O-N 3.06Å; A149-F316 HydrophobicContact CB-CD2 4.12Å; A149-F316 HydrophobicContact CB-CE2 3.58Å; A149-F316 HydrophobicContact CB-CZ 3.98Å; A149-M356 HydrophobicContact CB-CE 4.36Å; A149-M356 WeakPolarHBondContact O-CE 3.49Å; A149-L360 HydrophobicContact CB-CD2 4.48Å; A149-V368 HydrophobicContact CB-CG1 4.28Å; A149-L369 HydrophobicContact CB-CD1 3.82Å; A149-L369 HydrophobicContact CB-CD2 3.75Å; A149-L369 HydrophobicContact CB-CG 3.78Å
150A95.6Very high85.7Confident0 Ų011.9 Ų11.90%06%0.063CC..Hα-helixtrans-63.6-43.6176.900000111.7A146 E147 V148 L153 D154 F283 I287 N312A146-A150 WeakPolarHBondContact O-CB 3.47Å; A146-A150 PolarHBondContact O-N 3.49Å; E147-A150 PolarHBondContact O-N 2.69Å; V148-A150 PolarHBondContact O-N 3.45Å; A150-L153 PolarHBondContact O-N 3.4Å; A150-D154 WeakPolarHBondContact O-CB 3.36Å; A150-D154 PolarHBondContact O-N 3.25Å; A150-F283 HydrophobicContact CB-CE1 4.46Å; A150-F283 HydrophobicContact CB-CZ 3.88Å; A150-F283 WeakPolarHBondContact O-CZ 3.29Å; A150-I287 HydrophobicContact CB-CD1 4.41Å; A150-N312 HydrophobicContact CB-CB 3.37Å
151F94.1Very high85.3Confident1 Ų111.1 Ų11.10%0.0045%0.052CC..Hα-helixtrans-59.3-50.1173.3161.4-111.5000111.7Y77 L84 L88 E147 V148 L153 D154 I155 P165 L166 V167Y77-F151 HydrophobicContact CE1-CE2 4.15Å; L84-F151 HydrophobicContact CD1-CZ 4.42Å; L88-F151 HydrophobicContact CD1-CE1 3.99Å; L88-F151 HydrophobicContact CD1-CZ 4.2Å; L88-F151 HydrophobicContact CD2-CE1 3.99Å; L88-F151 HydrophobicContact CD2-CZ 4.1Å; E147-F151 PolarHBondContact O-N 2.72Å; V148-F151 PolarHBondContact O-N 2.94Å; F151-L153 PolarHBondContact O-N 2.65Å; F151-D154 PolarHBondContact O-N 2.93Å; F151-I155 HydrophobicContact CE2-CB 4.3Å; F151-I155 HydrophobicContact CE2-CD1 3.88Å; F151-I155 HydrophobicContact CZ-CD1 3.85Å; F151-I155 HydrophobicContact CZ-CG2 4.44Å; F151-I155 WeakPolarHBondContact O-CG2 3.5Å; F151-I155 PolarHBondContact O-N 3Å; F151-P165 VanDerWaalsContact CD2-O 3.26Å; F151-P165 WeakPolarHBondContact CD2-O 3.21Å; F151-L166 HydrophobicContact CE2-CD2 3.56Å; F151-L166 HydrophobicContact CZ-CD2 3.82Å; F151-V167 HydrophobicContact CB-CB 3.74Å; F151-V167 HydrophobicContact CB-CG2 3.8Å; F151-V167 HydrophobicContact CD1-CB 4.21Å; F151-V167 WeakPolarHBondContact CD1-O 3.23Å; F151-V167 WeakPolarHBondContact CE1-O 3.03Å; F151-V167 HydrophobicContact CG-CB 4.06Å; F151-V167 HydrophobicContact CG-CG2 4.34Å
152H91.6Very high85.1Confident4 Ų410.6 Ų10.62%0.0195%0.05CC..Hα-helixtrans-64.3-27.1179.6-82.5-76.9000113.2V148 A149 I155 L156 M356 A359 L360V148-H152 PolarHBondContact O-CD2 2.78Å; V148-H152 VanDerWaalsContact O-CD2 3.27Å; V148-H152 PolarHBondContact O-N 2.86Å; A149-H152 PolarHBondContact O-N 2.88Å; H152-I155 WeakPolarHBondContact O-CG2 3.26Å; H152-L156 WeakPolarHBondContact O-CB 3.46Å; H152-L156 PolarHBondContact O-N 3.22Å; H152-M356 HydrophobicContact CB-CE 3.35Å; H152-A359 HydrophobicContact CB-CB 4.45Å; H152-A359 PolarHBondContact CE1-O 3.49Å; H152-A359 PolarHBondContact ND1-O 3.39Å; H152-L360 HydrophobicContact CB-CD2 3.78Å
153L90Very high84.9Confident0 Ų010.3 Ų10.30%05%0.047CC..Hα-helixtrans-76.2-41174-176.267000111.8A149 A150 F151 L156 L159 F283 L286 I287 L352 M356 L377A149-L153 VanDerWaalsContact O-CB 3.31Å; A149-L153 WeakPolarHBondContact O-CB 3.47Å; A149-L153 PolarHBondContact O-N 3.06Å; A150-L153 PolarHBondContact O-N 3.4Å; F151-L153 PolarHBondContact O-N 2.65Å; L153-L156 WeakPolarHBondContact O-CB 3.31Å; L153-L156 PolarHBondContact O-N 3.06Å; L153-L159 HydrophobicContact CD1-CD1 3.38Å; L153-L159 HydrophobicContact CD2-CD1 4.23Å; L153-L159 HydrophobicContact CG-CD1 3.47Å; L153-L159 VanDerWaalsContact CG-CD1 3.47Å; L153-L159 WeakPolarHBondContact O-CD1 3.4Å; L153-F283 HydrophobicContact CB-CE2 4.16Å; L153-F283 HydrophobicContact CD2-CD2 4.14Å; L153-F283 HydrophobicContact CD2-CE2 3.91Å; L153-F283 HydrophobicContact CG-CD2 4.43Å; L153-F283 HydrophobicContact CG-CE2 4.06Å; L153-L286 HydrophobicContact CD2-CB 4.33Å; L153-I287 HydrophobicContact CD2-CG2 3.31Å; L153-L352 HydrophobicContact CD1-CD1 3.74Å; L153-M356 HydrophobicContact CB-CE 4.29Å; L153-M356 HydrophobicContact CB-SD 3.95Å; L153-M356 HydrophobicContact CD1-SD 3.98Å; L153-L377 HydrophobicContact CD2-CD2 4.39Å
154D84.5Confident84.7Confident0 Ų09.6 Ų9.60%05%0.045CC..Hα-helixtrans-62.5-42.5175.7172.369.4000111.9Y77 A150 F151 L156 F161 R162 R163 A164 F283 L309Y77-D154 PolarHBondContact OH-OD2 3.07Å; A150-D154 WeakPolarHBondContact O-CB 3.36Å; A150-D154 PolarHBondContact O-N 3.25Å; F151-D154 PolarHBondContact O-N 2.93Å; D154-L156 VanDerWaalsContact C-N 3.33Å; D154-F161 PolarHBondContact O-N 3.49Å; D154-F161 WeakPolarHBondContact OD1-CB 3.42Å; D154-R162 PolarHBondContact OD1-N 2.98Å; D154-R162 VanDerWaalsContact OD1-N 3.14Å; D154-R162 WeakPolarHBondContact OD2-CA 3.42Å; D154-R163 PolarHBondContact OD1-N 3.34Å; D154-R163 PolarHBondContact OD2-N 3.32Å; D154-A164 HydrophobicContact CB-CB 3.83Å; D154-A164 VanDerWaalsContact OD2-CB 3.31Å; D154-A164 WeakPolarHBondContact OD2-CB 3.43Å; D154-A164 PolarHBondContact OD2-N 3.4Å; D154-F283 HydrophobicContact CB-CE2 4.09Å; D154-F283 HydrophobicContact CB-CZ 4.47Å; D154-L309 HydrophobicContact CB-CD1 4.37Å; D154-L309 WeakPolarHBondContact OD1-CD1 3.49Å
155I74.1Confident84.6Confident30 Ų309.8 Ų9.815%0.1545%0.046CC..Hα-helixtrans-78.6-19177.1-161.9148.8000113Y77 L84 F151 H152 R157Y77-I155 HydrophobicContact CD2-CD1 3.86Å; Y77-I155 HydrophobicContact CD2-CG1 4.28Å; Y77-I155 HydrophobicContact CE1-CD1 4.26Å; Y77-I155 HydrophobicContact CE2-CB 3.97Å; Y77-I155 HydrophobicContact CE2-CD1 3.34Å; Y77-I155 HydrophobicContact CE2-CG1 3.4Å; Y77-I155 WeakPolarHBondContact OH-CA 3.47Å; Y77-I155 WeakPolarHBondContact OH-CB 3.48Å; Y77-I155 PolarHBondContact OH-N 2.92Å; Y77-I155 VanDerWaalsContact OH-N 3.16Å; L84-I155 HydrophobicContact CD1-CD1 4.18Å; L84-I155 HydrophobicContact CD2-CD1 3.36Å; L84-I155 HydrophobicContact CD2-CG1 4.41Å; L84-I155 HydrophobicContact CG-CD1 4.4Å; F151-I155 HydrophobicContact CE2-CB 4.3Å; F151-I155 HydrophobicContact CE2-CD1 3.88Å; F151-I155 HydrophobicContact CZ-CD1 3.85Å; F151-I155 HydrophobicContact CZ-CG2 4.44Å; F151-I155 WeakPolarHBondContact O-CG2 3.5Å; F151-I155 PolarHBondContact O-N 3Å; H152-I155 WeakPolarHBondContact O-CG2 3.26Å; I155-R157 VanDerWaalsContact O-CA 3.32Å; I155-R157 WeakPolarHBondContact O-CA 3.41Å; I155-R157 PolarHBondContact O-N 3.06Å
156L57.4Low84.5Confident2 Ų29.4 Ų9.41%0.014%0.044CC..SBendtrans-49.4111-179.1-159.8130.3000106.4L48 H152 L153 D154 I158 L159 G160 L347 L352 A355 M356L48-L156 HydrophobicContact CD2-CD1 4.38Å; L48-L156 HydrophobicContact CD2-CG 3.91Å; H152-L156 WeakPolarHBondContact O-CB 3.46Å; H152-L156 PolarHBondContact O-N 3.22Å; L153-L156 WeakPolarHBondContact O-CB 3.31Å; L153-L156 PolarHBondContact O-N 3.06Å; D154-L156 VanDerWaalsContact C-N 3.33Å; L156-I158 HydrophobicContact CD2-CB 4.16Å; L156-I158 CarbonylContact O-C 3.54Å; L156-I158 VanDerWaalsContact O-C 3.31Å; L156-I158 PolarHBondContact O-N 3.17Å; L156-L159 PolarHBondContact O-N 3.46Å; L156-G160 PolarHBondContact O-N 2.96Å; L156-L347 HydrophobicContact CD2-CD1 4.44Å; L156-L347 HydrophobicContact CD2-CD2 3.72Å; L156-L352 HydrophobicContact CD2-CD1 4.49Å; L156-A355 HydrophobicContact CD1-CB 3.86Å; L156-A355 HydrophobicContact CD2-CB 4.12Å; L156-A355 HydrophobicContact CG-CB 4.33Å; L156-M356 HydrophobicContact CD1-CB 4.44Å; L156-M356 HydrophobicContact CD1-SD 4.07Å
157R55.6Low84.5Confident50 Ų509.6 Ų9.619%0.1895%0.045CC..THydrogen-bonded Turntrans-57.9-18.9-157.7-166.3165-174.8171.515.7112.7M44 E79 I155 R343M44-R157 HydrophobicContact CB-CB 4.33Å; M44-R157 HydrophobicContact CG-CB 3.86Å; E79-R157 PolarHBondContact O-NH2 3.38Å; I155-R157 VanDerWaalsContact O-CA 3.32Å; I155-R157 WeakPolarHBondContact O-CA 3.41Å; I155-R157 PolarHBondContact O-N 3.06Å; R157-R343 PolarHBondContact O-NH1 3.29Å
158I51.5Low84.5Confident10 Ų109.3 Ų9.35%0.0514%0.044CC..THydrogen-bonded Turntrans-73-56.7166.1-64.8165.9000113.7F41 M44 L156 G160 R343 F346 L347F41-I158 HydrophobicContact CE2-CD1 4.48Å; M44-I158 HydrophobicContact CB-CG1 4.24Å; M44-I158 HydrophobicContact CE-CD1 3.14Å; M44-I158 HydrophobicContact CE-CG1 3.69Å; M44-I158 HydrophobicContact CG-CD1 4.13Å; M44-I158 HydrophobicContact CG-CG1 3.64Å; M44-I158 HydrophobicContact SD-CD1 3.42Å; M44-I158 WeakPolarHBondContact SD-CD1 3.41Å; M44-I158 HydrophobicContact SD-CG1 3.66Å; L156-I158 HydrophobicContact CD2-CB 4.16Å; L156-I158 CarbonylContact O-C 3.54Å; L156-I158 VanDerWaalsContact O-C 3.31Å; L156-I158 PolarHBondContact O-N 3.17Å; I158-G160 PolarHBondContact O-N 3.22Å; I158-R343 HydrophobicContact CG2-CB 3.68Å; I158-R343 HydrophobicContact CG2-CG 4.18Å; I158-R343 WeakPolarHBondContact CG2-O 3.41Å; I158-R343 WeakPolarHBondContact O-CB 3.49Å; I158-R343 WeakPolarHBondContact O-CD 3.45Å; I158-R343 WeakPolarHBondContact O-CG 3.39Å; I158-R343 PolarHBondContact O-NH1 2.89Å; I158-F346 HydrophobicContact CD1-CB 4.32Å; I158-F346 HydrophobicContact CG2-CB 4.4Å; I158-L347 HydrophobicContact CB-CD1 3.97Å; I158-L347 HydrophobicContact CB-CD2 3.91Å; I158-L347 HydrophobicContact CB-CG 3.93Å; I158-L347 HydrophobicContact CD1-CD2 3.3Å; I158-L347 HydrophobicContact CD1-CG 3.79Å; I158-L347 HydrophobicContact CG1-CD2 4.2Å; I158-L347 HydrophobicContact CG1-CG 4.47Å; I158-L347 HydrophobicContact CG2-CD1 3.56Å; I158-L347 HydrophobicContact CG2-CD2 4.09Å; I158-L347 HydrophobicContact CG2-CG 3.53Å
159L70.9Confident84.5Confident2 Ų29.3 Ų9.31%0.014%0.044CC..THydrogen-bonded Turntrans-58.6-42.9178.6-81.8172.3000110.4L153 L156 F161 L286 R343 L344 L347L153-L159 HydrophobicContact CD1-CD1 3.38Å; L153-L159 HydrophobicContact CD2-CD1 4.23Å; L153-L159 HydrophobicContact CG-CD1 3.47Å; L153-L159 VanDerWaalsContact CG-CD1 3.47Å; L153-L159 WeakPolarHBondContact O-CD1 3.4Å; L156-L159 PolarHBondContact O-N 3.46Å; L159-F161 HydrophobicContact CB-CD2 4.27Å; L159-F161 HydrophobicContact CB-CE2 4.4Å; L159-F161 HydrophobicContact CD2-CE2 3.94Å; L159-F161 HydrophobicContact CD2-CZ 4.26Å; L159-F161 PolarHBondContact O-N 2.84Å; L159-L286 HydrophobicContact CD1-CD1 4.29Å; L159-L286 HydrophobicContact CD2-CD1 4.45Å; L159-R343 WeakPolarHBondContact O-CD 3.32Å; L159-L344 HydrophobicContact CD2-CD2 3.73Å; L159-L347 HydrophobicContact CD2-CD1 4.31Å; L159-L347 HydrophobicContact CG-CD1 4.01Å
160G72.3Confident84.6Confident11 Ų119.9 Ų9.911%0.1135%0.046CC..  trans55.330.4163.400000113.7L156 I158 R162L156-G160 PolarHBondContact O-N 2.96Å; I158-G160 PolarHBondContact O-N 3.22Å; G160-R162 PolarHBondContact O-NH1 2.9Å
161F83.9Confident84.8Confident13 Ų1315.2 Ų15.26%0.0577%0.067CC..  trans-70.2-42.9176.8-71.7-41.6000109.8D154 L159 R163 D279 F283 T340D154-F161 PolarHBondContact O-N 3.49Å; D154-F161 WeakPolarHBondContact OD1-CB 3.42Å; L159-F161 HydrophobicContact CB-CD2 4.27Å; L159-F161 HydrophobicContact CB-CE2 4.4Å; L159-F161 HydrophobicContact CD2-CE2 3.94Å; L159-F161 HydrophobicContact CD2-CZ 4.26Å; L159-F161 PolarHBondContact O-N 2.84Å; F161-R163 VanDerWaalsContact C-N 3.28Å; F161-R163 HydrophobicContact CB-CG 4.01Å; F161-R163 WeakPolarHBondContact O-CG 3.48Å; F161-R163 PolarHBondContact O-N 2.92Å; F161-D279 HydrophobicContact CD1-CB 4.31Å; F161-D279 HydrophobicContact CE1-CB 3.63Å; F161-D279 VanDerWaalsContact CE1-CG 3.48Å; F161-D279 HydrophobicContact CZ-CB 3.9Å; F161-F283 HydrophobicContact CD2-CB 4.43Å; F161-F283 HydrophobicContact CD2-CD2 4.26Å; F161-F283 HydrophobicContact CE2-CB 4.01Å; F161-F283 HydrophobicContact CE2-CD2 4.41Å; F161-T340 HydrophobicContact CE1-CG2 3.91Å; F161-T340 HydrophobicContact CZ-CG2 3.85Å
162R90.2Very high84.9Confident43 Ų4315.2 Ų15.216%0.1627%0.067CC..  trans56.441.9177.6-49-170.5-63.2-72.4-1.4112.5E75 V76 Y77 D154 G160E75-R162 CarbonylContact C-O 3.59Å; E75-R162 WeakPolarHBondContact CA-O 3.4Å; E75-R162 HydrophobicContact CB-CB 4.23Å; E75-R162 IonicContact OE2-CZ 2.57Å; E75-R162 IonicContact OE2-NE 3.63Å; E75-R162 PolarHBondContact OE2-NE 2.89Å; E75-R162 VanDerWaalsContact OE2-NE 3.1Å; E75-R162 IonicContact OE2-NH2 3.63Å; E75-R162 PolarHBondContact OE2-NH2 2.81Å; V76-R162 PolarHBondContact N-O 3.05Å; Y77-R162 HydrophobicContact CD2-CB 4.05Å; Y77-R162 HydrophobicContact CD2-CG 4.05Å; Y77-R162 HydrophobicContact CE2-CB 3.62Å; Y77-R162 HydrophobicContact CE2-CG 3.48Å; Y77-R162 VanDerWaalsContact CE2-CG 3.48Å; Y77-R162 WeakPolarHBondContact O-CD 3.13Å; Y77-R162 PolarHBondContact O-NE 2.99Å; Y77-R162 WeakPolarHBondContact OH-CA 3.34Å; D154-R162 PolarHBondContact OD1-N 2.98Å; D154-R162 VanDerWaalsContact OD1-N 3.14Å; D154-R162 WeakPolarHBondContact OD2-CA 3.42Å; G160-R162 PolarHBondContact O-NH1 2.9Å
163R92.7Very high85.2Confident13 Ų1316.7 Ų16.75%0.0498%0.075CC..  trans-115.7-7.8-173.6-48.7-167.5-172.4157.5-6.7113.3D154 F161 D276 D279 M306 L307 I308 L309D154-R163 PolarHBondContact OD1-N 3.34Å; D154-R163 PolarHBondContact OD2-N 3.32Å; F161-R163 VanDerWaalsContact C-N 3.28Å; F161-R163 HydrophobicContact CB-CG 4.01Å; F161-R163 WeakPolarHBondContact O-CG 3.48Å; F161-R163 PolarHBondContact O-N 2.92Å; R163-D276 IonicContact CZ-OD1 3.12Å; R163-D276 PolarHBondContact NH1-O 2.97Å; R163-D276 IonicContact NH1-OD1 3.47Å; R163-D276 IonicContact NH2-OD1 3.4Å; R163-D276 PolarHBondContact NH2-OD1 3.32Å; R163-D279 IonicContact CZ-OD2 2.65Å; R163-D279 IonicContact NH1-OD2 2.86Å; R163-D279 IonicContact NH2-OD2 3.82Å; R163-D279 PolarHBondContact NH2-OD2 3.48Å; R163-M306 HydrophobicContact CB-CE 4.43Å; R163-M306 HydrophobicContact CB-SD 4.06Å; R163-M306 HydrophobicContact CG-CE 4.46Å; R163-M306 HydrophobicContact CG-SD 3.56Å; R163-M306 VanDerWaalsContact CG-SD 3.56Å; R163-L307 WeakPolarHBondContact CB-O 3.42Å; R163-L307 WeakPolarHBondContact CD-O 3.22Å; R163-I308 WeakPolarHBondContact O-CA 3.46Å; R163-I308 WeakPolarHBondContact O-CG2 3.37Å; R163-L309 HydrophobicContact CB-CB 4.46Å; R163-L309 HydrophobicContact CB-CD1 4.08Å; R163-L309 HydrophobicContact CB-CG 3.91Å; R163-L309 PolarHBondContact O-N 3.48Å
164A93.3Very high85.6Confident1 Ų116.7 Ų16.71%0.0088%0.075CC..SBendtrans-91.3147.1176.600000110.9Y77 D154 L309Y77-A164 WeakPolarHBondContact CE1-O 3.44Å; D154-A164 HydrophobicContact CB-CB 3.83Å; D154-A164 VanDerWaalsContact OD2-CB 3.31Å; D154-A164 WeakPolarHBondContact OD2-CB 3.43Å; D154-A164 PolarHBondContact OD2-N 3.4Å; A164-L309 HydrophobicContact CB-CB 4.1Å
165P94.4Very high86.1Confident6 Ų623.8 Ų23.84%0.03910%0.102CC..PPolyproline II helixtrans-64.1162.2167.429.9-36.2000111F151 V167 T224 L227 L310F151-P165 VanDerWaalsContact CD2-O 3.26Å; F151-P165 WeakPolarHBondContact CD2-O 3.21Å; P165-V167 PolarHBondContact O-N 3.32Å; P165-T224 HydrophobicContact CB-CG2 3.82Å; P165-T224 HydrophobicContact CG-CG2 3.44Å; P165-T224 VanDerWaalsContact CG-CG2 3.44Å; P165-L227 HydrophobicContact CB-CD2 4.42Å; P165-L310 HydrophobicContact CG-CD2 3.64Å
166L95.4Very high87.2Confident6 Ų626.7 Ų26.73%0.03112%0.121CC..PPolyproline II helixtrans-67.2131.1175.3-55.8-176.8000110.3A67 W70 Y77 L84 V87 L88 F151 T224 L225A67-L166 HydrophobicContact CB-CD1 4.22Å; W70-L166 HydrophobicContact CZ3-CD1 3.99Å; Y77-L166 HydrophobicContact CD1-CD2 3.9Å; Y77-L166 HydrophobicContact CE1-CD2 4.32Å; L84-L166 HydrophobicContact CD1-CD1 4.47Å; L84-L166 HydrophobicContact CD1-CD2 3.76Å; V87-L166 HydrophobicContact CG1-CD1 3.64Å; L88-L166 HydrophobicContact CD2-CB 4.13Å; F151-L166 HydrophobicContact CE2-CD2 3.56Å; F151-L166 HydrophobicContact CZ-CD2 3.82Å; L166-T224 WeakPolarHBondContact O-CA 3.24Å; L166-L225 HydrophobicContact CB-CB 4.12Å; L166-L225 HydrophobicContact CB-CD2 4.41Å; L166-L225 HydrophobicContact CD1-CD2 3.95Å; L166-L225 HydrophobicContact CG-CD2 4.38Å; L166-L225 PolarHBondContact O-N 3.04Å
167V96.6Very high89.1Confident3 Ų329.2 Ų29.22%0.01813%0.132CC..EExtended strand (participates in β ladder)trans-130.1137.5178.3-170.90000110.3E147 V148 F151 P165 L223 T224E147-V167 HydrophobicContact CB-CG1 3.98Å; V148-V167 HydrophobicContact CB-CG1 4.45Å; V148-V167 HydrophobicContact CG2-CG1 3.84Å; F151-V167 HydrophobicContact CB-CB 3.74Å; F151-V167 HydrophobicContact CB-CG2 3.8Å; F151-V167 HydrophobicContact CD1-CB 4.21Å; F151-V167 WeakPolarHBondContact CD1-O 3.23Å; F151-V167 WeakPolarHBondContact CE1-O 3.03Å; F151-V167 HydrophobicContact CG-CB 4.06Å; F151-V167 HydrophobicContact CG-CG2 4.34Å; P165-V167 PolarHBondContact O-N 3.32Å; V167-L223 CarbonylContact C-O 3.59Å; V167-L223 VanDerWaalsContact CA-O 3.26Å; V167-L223 WeakPolarHBondContact CA-O 3.3Å; V167-T224 HydrophobicContact CG2-CG2 4.01Å
168V97.3Very high91.2Very high1 Ų127.1 Ų27.11%0.00613%0.125CC..EExtended strand (participates in β ladder)trans-136.4147.2172.376.70000110.9L91 S222 L223 P364L91-V168 HydrophobicContact CB-CG1 3.81Å; L91-V168 HydrophobicContact CD2-CB 4.11Å; L91-V168 HydrophobicContact CD2-CG1 3.58Å; L91-V168 HydrophobicContact CG-CG1 3.55Å; V168-S222 WeakPolarHBondContact O-CA 3.14Å; V168-L223 HydrophobicContact CG1-CB 4.21Å; V168-L223 PolarHBondContact N-O 2.89Å; V168-L223 PolarHBondContact O-N 2.97Å; V168-P364 HydrophobicContact CG2-CG 4.27Å
169G98Very high93.3Very high0 Ų029.9 Ų29.90%014%0.137CC..EExtended strand (participates in β ladder)trans-72.3143166.400000112.2G221 D363 P364G169-G221 WeakPolarHBondContact CA-O 3.48Å; G169-D363 WeakPolarHBondContact CA-OD1 3.48Å; G169-D363 PolarHBondContact N-OD1 2.76Å; G169-D363 PolarHBondContact N-OD2 2.94Å; G169-P364 WeakPolarHBondContact O-CG 3.36Å
170R97.9Very high94.6Very high11 Ų1134.2 Ų34.24%0.04217%0.165CC..EExtended strand (participates in β ladder)trans-146.6141.9174.7-174.4178.1175.3158.7-4.8111.8L91 S92 A94 V172 E177 G221 L223L91-R170 PolarHBondContact O-NH1 3.26Å; S92-R170 VanDerWaalsContact O-CD 3.24Å; S92-R170 WeakPolarHBondContact O-CD 3.36Å; S92-R170 WeakPolarHBondContact O-CG 3.29Å; S92-R170 PolarHBondContact O-NE 3.43Å; A94-R170 VanDerWaalsContact O-CZ 3.28Å; A94-R170 PolarHBondContact O-NH1 3.12Å; A94-R170 PolarHBondContact O-NH2 3.41Å; R170-V172 HydrophobicContact CB-CG2 4.43Å; R170-V172 HydrophobicContact CG-CG2 3.85Å; R170-E177 IonicContact CZ-OE2 2.67Å; R170-E177 IonicContact NE-OE2 3.77Å; R170-E177 IonicContact NH2-OE2 3.94Å; R170-E177 PolarHBondContact NH2-OE2 3.03Å; R170-G221 PolarHBondContact N-O 3.4Å; R170-G221 PolarHBondContact O-N 3.23Å; R170-L223 HydrophobicContact CB-CD1 4.01Å; R170-L223 HydrophobicContact CB-CG 4.32Å; R170-L223 HydrophobicContact CG-CD1 4.35Å
171Y98.1Very high95.8Very high113 Ų11335.5 Ų35.544%0.44317%0.171SC..EExtended strand (participates in β ladder)trans-92124.9163.3-64.6-82.3000109T218 M219 E220 I365Y171-T218 HydrophobicContact CD1-CG2 4.12Å; Y171-T218 HydrophobicContact CG-CG2 4.45Å; Y171-M219 WeakPolarHBondContact CA-O 3.29Å; Y171-E220 HydrophobicContact CD1-CB 3.88Å; Y171-E220 HydrophobicContact CD1-CG 4.06Å; Y171-E220 HydrophobicContact CE1-CB 3.69Å; Y171-E220 HydrophobicContact CE1-CG 3.58Å; Y171-I365 HydrophobicContact CD2-CG2 4.28Å; Y171-I365 HydrophobicContact CE2-CB 4.42Å; Y171-I365 HydrophobicContact CE2-CG2 3.8Å
172V97.4Very high96.5Very high0 Ų035.7 Ų35.70%017%0.174CC..EExtended strand (participates in β ladder)trans-121.6126.8-176.9-1780000109.1I96 F122 R170 L174 E177 I178 M219I96-V172 HydrophobicContact CD1-CG1 3.87Å; I96-V172 HydrophobicContact CD1-CG2 4.4Å; F122-V172 HydrophobicContact CE2-CG2 3.95Å; F122-V172 HydrophobicContact CZ-CG2 4.36Å; R170-V172 HydrophobicContact CB-CG2 4.43Å; R170-V172 HydrophobicContact CG-CG2 3.85Å; V172-L174 PolarHBondContact O-N 2.8Å; V172-E177 HydrophobicContact CG1-CB 3.97Å; V172-I178 HydrophobicContact CG1-CD1 3.8Å; V172-I178 HydrophobicContact CG1-CG1 3.56Å; V172-M219 PolarHBondContact N-O 3.01Å; V172-M219 PolarHBondContact O-N 2.95Å
173N97.8Very high96.8Very high35 Ų3536 Ų3619%0.18718%0.181CC..EExtended strand (participates in β ladder)trans-79.5112.6171.9-175.7-52.1000110R175 T176 E177 I178 E217N173-R175 PolarHBondContact O-N 3.48Å; N173-R175 WeakPolarHBondContact OD1-CA 3.3Å; N173-R175 WeakPolarHBondContact OD1-CB 3.17Å; N173-R175 PolarHBondContact OD1-N 3.13Å; N173-T176 VanDerWaalsContact CB-OG1 3.26Å; N173-T176 WeakPolarHBondContact CB-OG1 3.21Å; N173-T176 PolarHBondContact O-N 3.43Å; N173-T176 PolarHBondContact OD1-N 3.06Å; N173-T176 PolarHBondContact OD1-OG1 2.7Å; N173-E177 HydrophobicContact CB-CG 4.48Å; N173-E177 PolarHBondContact N-OE1 3.27Å; N173-E177 WeakPolarHBondContact O-CA 3.49Å; N173-E177 VanDerWaalsContact O-CB 3.31Å; N173-E177 WeakPolarHBondContact O-CB 3.38Å; N173-E177 PolarHBondContact O-N 2.81Å; N173-I178 PolarHBondContact O-N 3.49Å; N173-E217 WeakPolarHBondContact CA-O 3.09Å
174L97.6Very high96.9Very high0 Ų042 Ų420%021%0.214CC..Iπ-helixtrans-64.7-28.9-175.7-63.5-177000113V172 I178 K179 F190 T197 F199 A214 E217 M219V172-L174 PolarHBondContact O-N 2.8Å; L174-I178 HydrophobicContact CD2-CB 4.32Å; L174-I178 HydrophobicContact CD2-CG1 3.92Å; L174-K179 WeakPolarHBondContact O-CB 3.49Å; L174-K179 VanDerWaalsContact O-CG 3.3Å; L174-K179 WeakPolarHBondContact O-CG 3.24Å; L174-K179 PolarHBondContact O-N 3.02Å; L174-F190 HydrophobicContact CB-CE1 4.19Å; L174-F190 HydrophobicContact CD1-CE1 4.13Å; L174-T197 HydrophobicContact CB-CG2 4.08Å; L174-T197 HydrophobicContact CD1-CG2 3.84Å; L174-F199 HydrophobicContact CD1-CD1 4.42Å; L174-F199 HydrophobicContact CD2-CE1 4.29Å; L174-A214 HydrophobicContact CD1-CB 3.78Å; L174-A214 HydrophobicContact CG-CB 4.4Å; L174-E217 PolarHBondContact N-O 3.28Å; L174-M219 HydrophobicContact CD1-CB 4.16Å; L174-M219 HydrophobicContact CD1-CE 3.84Å; L174-M219 HydrophobicContact CD1-SD 4.3Å; L174-M219 HydrophobicContact CD2-CB 3.96Å; L174-M219 HydrophobicContact CD2-SD 4.13Å; L174-M219 HydrophobicContact CG-CB 3.96Å
175R96.1Very high97Very high150 Ų15046.1 Ų46.157%0.56623%0.233SC*.Iπ-helixtrans-81.3-39.8-178.1179.7176.1177.3-169.9-0.5112.8N173 P180 E217N173-R175 PolarHBondContact O-N 3.48Å; N173-R175 WeakPolarHBondContact OD1-CA 3.3Å; N173-R175 WeakPolarHBondContact OD1-CB 3.17Å; N173-R175 PolarHBondContact OD1-N 3.13Å; R175-P180 VanDerWaalsContact O-CD 3.25Å; R175-P180 WeakPolarHBondContact O-CD 3.28Å; R175-P180 WeakPolarHBondContact O-CG 3.27Å; R175-E217 HydrophobicContact CB-CG 4.42Å; R175-E217 VanDerWaalsContact CD-CD 3.44Å; R175-E217 WeakPolarHBondContact CD-OE1 3.12Å; R175-E217 WeakPolarHBondContact CD-OE2 3.49Å; R175-E217 IonicContact CZ-OE1 2.81Å; R175-E217 IonicContact NE-OE1 3.96Å; R175-E217 IonicContact NH1-OE1 3.82Å; R175-E217 PolarHBondContact NH1-OE1 3.1Å
176T97.4Very high97Very high90 Ų9046 Ų4655%0.55223%0.232SC*.Iπ-helixtrans-98.2-30-174.259.50000113N173N173-T176 VanDerWaalsContact CB-OG1 3.26Å; N173-T176 WeakPolarHBondContact CB-OG1 3.21Å; N173-T176 PolarHBondContact O-N 3.43Å; N173-T176 PolarHBondContact OD1-N 3.06Å; N173-T176 PolarHBondContact OD1-OG1 2.7Å
177E97.8Very high97.1Very high55 Ų5548.7 Ų48.726%0.25725%0.247SC..Iπ-helixtrans-105.2-28-175.7-62.5178.3-9600114I96 R170 V172 N173 V181I96-E177 HydrophobicContact CD1-CB 4.26Å; R170-E177 IonicContact CZ-OE2 2.67Å; R170-E177 IonicContact NE-OE2 3.77Å; R170-E177 IonicContact NH2-OE2 3.94Å; R170-E177 PolarHBondContact NH2-OE2 3.03Å; V172-E177 HydrophobicContact CG1-CB 3.97Å; N173-E177 HydrophobicContact CB-CG 4.48Å; N173-E177 PolarHBondContact N-OE1 3.27Å; N173-E177 WeakPolarHBondContact O-CA 3.49Å; N173-E177 VanDerWaalsContact O-CB 3.31Å; N173-E177 WeakPolarHBondContact O-CB 3.38Å; N173-E177 PolarHBondContact O-N 2.81Å; E177-V181 WeakPolarHBondContact O-CG2 3.31Å
178I97.8Very high97Very high6 Ų652 Ų523%0.03127%0.27CS..Iπ-helixtrans-104.1-62.6-176.6-60.2-61.4000112.5I96 A99 L112 V172 N173 L174 P180 V181 A182 L186 F190I96-I178 HydrophobicContact CD1-CD1 3.88Å; I96-I178 HydrophobicContact CG2-CD1 4.33Å; A99-I178 HydrophobicContact CB-CD1 4.23Å; A99-I178 HydrophobicContact CB-CG2 3.99Å; L112-I178 HydrophobicContact CD1-CD1 4.21Å; L112-I178 HydrophobicContact CD2-CD1 3.74Å; V172-I178 HydrophobicContact CG1-CD1 3.8Å; V172-I178 HydrophobicContact CG1-CG1 3.56Å; N173-I178 PolarHBondContact O-N 3.49Å; L174-I178 HydrophobicContact CD2-CB 4.32Å; L174-I178 HydrophobicContact CD2-CG1 3.92Å; I178-P180 VanDerWaalsContact C-N 3.34Å; I178-V181 CarbonylContact O-C 3.57Å; I178-V181 WeakPolarHBondContact O-CG2 3.18Å; I178-V181 PolarHBondContact O-N 2.75Å; I178-A182 HydrophobicContact CG2-CB 4.43Å; I178-A182 WeakPolarHBondContact O-CB 3.46Å; I178-A182 PolarHBondContact O-N 3.27Å; I178-L186 HydrophobicContact CG2-CD2 4.19Å; I178-F190 HydrophobicContact CG2-CE2 4.41Å; I178-F190 HydrophobicContact CG2-CZ 3.91Å
179K96.9Very high96.9Very high68 Ų6852 Ų5230%0.29627%0.27SS..G310 helixtrans-51.5-41.4-174.4-77.1178.9-179.4178.10114.3L174 V181 A182 L187 F190L174-K179 WeakPolarHBondContact O-CB 3.49Å; L174-K179 VanDerWaalsContact O-CG 3.3Å; L174-K179 WeakPolarHBondContact O-CG 3.24Å; L174-K179 PolarHBondContact O-N 3.02Å; K179-V181 PolarHBondContact O-N 3.25Å; K179-A182 PolarHBondContact O-N 2.99Å; K179-L187 HydrophobicContact CB-CD2 4.2Å; K179-L187 HydrophobicContact CG-CD2 4.13Å; K179-F190 HydrophobicContact CG-CD1 4.44Å; K179-F190 HydrophobicContact CG-CE1 4.12Å; K179-F190 HydrophobicContact CG-CE2 4.31Å; K179-F190 HydrophobicContact CG-CZ 4.05Å
180P97.8Very high96.9Very high93 Ų9353.7 Ų53.760%0.60428%0.277SS*.G310 helixtrans-68.7-18.8-177.9-22.136.1000114.5R175 I178R175-P180 VanDerWaalsContact O-CD 3.25Å; R175-P180 WeakPolarHBondContact O-CD 3.28Å; R175-P180 WeakPolarHBondContact O-CG 3.27Å; I178-P180 VanDerWaalsContact C-N 3.34Å
181V97.9Very high96.9Very high39 Ų3954.8 Ų54.824%0.23628%0.283CS..G310 helixtrans-119.97.9-176.3-61.20000112.4I96 E97 R98 A99 E177 I178 K179I96-V181 HydrophobicContact CG2-CG2 4.07Å; E97-V181 WeakPolarHBondContact O-CB 3.47Å; E97-V181 WeakPolarHBondContact O-CG1 3.07Å; R98-V181 WeakPolarHBondContact CA-O 3.38Å; A99-V181 HydrophobicContact CB-CG2 4.31Å; A99-V181 PolarHBondContact N-O 3.33Å; E177-V181 WeakPolarHBondContact O-CG2 3.31Å; I178-V181 CarbonylContact O-C 3.57Å; I178-V181 WeakPolarHBondContact O-CG2 3.18Å; I178-V181 PolarHBondContact O-N 2.75Å; K179-V181 PolarHBondContact O-N 3.25Å
182A97.5Very high96.8Very high16 Ų1654.7 Ų54.713%0.13229%0.288CS..BIsolated β-bridgetrans-82.1144.9-17800000111.8A99 I178 K179 L186 L187A99-A182 HydrophobicContact CB-CB 4.26Å; A99-A182 CarbonylContact O-C 3.48Å; A99-A182 VanDerWaalsContact O-CA 3.22Å; A99-A182 WeakPolarHBondContact O-CA 3.42Å; I178-A182 HydrophobicContact CG2-CB 4.43Å; I178-A182 WeakPolarHBondContact O-CB 3.46Å; I178-A182 PolarHBondContact O-N 3.27Å; K179-A182 PolarHBondContact O-N 2.99Å; A182-L186 HydrophobicContact CB-CB 4.4Å; A182-L186 HydrophobicContact CB-CD2 3.97Å; A182-L186 HydrophobicContact CB-CG 4.32Å; A182-L187 HydrophobicContact CB-CD2 3.86Å; A182-L187 HydrophobicContact CB-CG 3.79Å
183T96.9Very high96.6Very high51 Ų5159 Ų5931%0.31331%0.308SS..  trans-66.4155.316963.40000111A99 D100 Q185 L186 L187A99-T183 PolarHBondContact O-N 3.06Å; D100-T183 HydrophobicContact CB-CG2 3.81Å; D100-T183 VanDerWaalsContact CG-CG2 3.45Å; D100-T183 WeakPolarHBondContact OD1-CG2 3.5Å; D100-T183 PolarHBondContact OD1-OG1 2.81Å; T183-Q185 PolarHBondContact O-N 2.85Å; T183-Q185 VanDerWaalsContact O-N 3.12Å; T183-L186 PolarHBondContact O-N 3.44Å; T183-L186 PolarHBondContact OG1-N 3.31Å; T183-L187 WeakPolarHBondContact O-CG 3.25Å; T183-L187 PolarHBondContact O-N 2.73Å
184D96.1Very high96.4Very high138 Ų13860.6 Ų60.674%0.73833%0.333SS*.Hα-helixtrans-54.7-33.1173.8-66.9-28.8000112L187 S188D184-L187 PolarHBondContact O-N 3.26Å; D184-S188 WeakPolarHBondContact O-CB 3.13Å; D184-S188 PolarHBondContact O-N 2.96Å
185Q93.6Very high96.2Very high88 Ų8867.6 Ų67.641%0.41137%0.371SS..Hα-helixtrans-65.3-37.9178.1179.1165.3-300113.3V101 T183 S188 T189 K202V101-Q185 HydrophobicContact CG1-CG 4.18Å; V101-Q185 VanDerWaalsContact CG2-CD 3.47Å; V101-Q185 HydrophobicContact CG2-CG 3.68Å; V101-Q185 VanDerWaalsContact CG2-NE2 3.3Å; T183-Q185 PolarHBondContact O-N 2.85Å; T183-Q185 VanDerWaalsContact O-N 3.12Å; Q185-S188 PolarHBondContact O-OG 2.88Å; Q185-T189 WeakPolarHBondContact O-CG2 3.24Å; Q185-K202 HydrophobicContact CG-CD 3.75Å
186L95.2Very high96.2Very high3 Ų363 Ų632%0.01636%0.358CS..Hα-helixtrans-78.5-43.4174.5177.859.7000110.4A99 V101 I178 A182 T183 S188 T189 F190 F199A99-L186 HydrophobicContact CB-CD2 3.86Å; V101-L186 HydrophobicContact CG1-CB 4.01Å; V101-L186 HydrophobicContact CG1-CD1 3.92Å; I178-L186 HydrophobicContact CG2-CD2 4.19Å; A182-L186 HydrophobicContact CB-CB 4.4Å; A182-L186 HydrophobicContact CB-CD2 3.97Å; A182-L186 HydrophobicContact CB-CG 4.32Å; T183-L186 PolarHBondContact O-N 3.44Å; T183-L186 PolarHBondContact OG1-N 3.31Å; L186-S188 VanDerWaalsContact C-N 3.27Å; L186-S188 PolarHBondContact O-N 3.13Å; L186-T189 PolarHBondContact O-N 2.79Å; L186-T189 PolarHBondContact O-OG1 2.91Å; L186-F190 HydrophobicContact CD1-CE2 4.42Å; L186-F190 HydrophobicContact CG-CE2 4.06Å; L186-F190 WeakPolarHBondContact O-CD2 3.36Å; L186-F199 HydrophobicContact CD1-CD2 4.12Å; L186-F199 HydrophobicContact CD1-CE2 4.5Å
187L96.8Very high96.2Very high63 Ų6359 Ų5933%0.3333%0.333SS..Hα-helixtrans-56-40178.5-74.6174000112.5K179 A182 T183 D184 T189 F190K179-L187 HydrophobicContact CB-CD2 4.2Å; K179-L187 HydrophobicContact CG-CD2 4.13Å; A182-L187 HydrophobicContact CB-CD2 3.86Å; A182-L187 HydrophobicContact CB-CG 3.79Å; T183-L187 WeakPolarHBondContact O-CG 3.25Å; T183-L187 PolarHBondContact O-N 2.73Å; D184-L187 PolarHBondContact O-N 3.26Å; L187-T189 PolarHBondContact O-N 2.84Å; L187-F190 PolarHBondContact O-N 3.06Å; L187-F190 VanDerWaalsContact O-N 3.16Å
188S96Very high96.2Very high73 Ų7356.3 Ų56.351%0.5132%0.321SS..THydrogen-bonded Turntrans-64.5-9.5178.279.90000114.3D184 Q185 L186D184-S188 WeakPolarHBondContact O-CB 3.13Å; D184-S188 PolarHBondContact O-N 2.96Å; Q185-S188 PolarHBondContact O-OG 2.88Å; L186-S188 VanDerWaalsContact C-N 3.27Å; L186-S188 PolarHBondContact O-N 3.13Å
189T95.4Very high96.1Very high0 Ų056.3 Ų56.30%032%0.32CS..THydrogen-bonded Turntrans-103.2-2.3-17973.70000113.2Q185 L186 L187 F199 Y200 G201 K202Q185-T189 WeakPolarHBondContact O-CG2 3.24Å; L186-T189 PolarHBondContact O-N 2.79Å; L186-T189 PolarHBondContact O-OG1 2.91Å; L187-T189 PolarHBondContact O-N 2.84Å; T189-F199 WeakPolarHBondContact O-CA 3.16Å; T189-Y200 HydrophobicContact CG2-CD2 4.4Å; T189-Y200 HydrophobicContact CG2-CE1 4.44Å; T189-Y200 HydrophobicContact CG2-CE2 3.84Å; T189-Y200 WeakPolarHBondContact O-CD1 3.14Å; T189-Y200 VanDerWaalsContact O-CE1 3.28Å; T189-Y200 WeakPolarHBondContact O-CE1 3.29Å; T189-Y200 PolarHBondContact O-N 2.99Å; T189-G201 WeakPolarHBondContact CG2-O 3.4Å; T189-G201 PolarHBondContact OG1-N 2.97Å; T189-K202 HydrophobicContact CG2-CG 4.07Å
190F97.2Very high96Very high36 Ų3655.4 Ų55.416%0.15832%0.315CS..EExtended strand (participates in β ladder)trans-76.4140.3176.4-85.3-93.7000111.3L174 I178 K179 L186 L187 T197 C198 F199L174-F190 HydrophobicContact CB-CE1 4.19Å; L174-F190 HydrophobicContact CD1-CE1 4.13Å; I178-F190 HydrophobicContact CG2-CE2 4.41Å; I178-F190 HydrophobicContact CG2-CZ 3.91Å; K179-F190 HydrophobicContact CG-CD1 4.44Å; K179-F190 HydrophobicContact CG-CE1 4.12Å; K179-F190 HydrophobicContact CG-CE2 4.31Å; K179-F190 HydrophobicContact CG-CZ 4.05Å; L186-F190 HydrophobicContact CD1-CE2 4.42Å; L186-F190 HydrophobicContact CG-CE2 4.06Å; L186-F190 WeakPolarHBondContact O-CD2 3.36Å; L187-F190 PolarHBondContact O-N 3.06Å; L187-F190 VanDerWaalsContact O-N 3.16Å; F190-T197 HydrophobicContact CD1-CG2 3.64Å; F190-T197 HydrophobicContact CE1-CG2 3.81Å; F190-C198 VanDerWaalsContact CA-O 3.3Å; F190-C198 WeakPolarHBondContact CA-O 3.45Å; F190-C198 WeakPolarHBondContact CD1-O 2.94Å; F190-F199 HydrophobicContact CD1-CB 4.1Å; F190-F199 HydrophobicContact CD2-CB 4.19Å; F190-F199 HydrophobicContact CE1-CB 4.17Å; F190-F199 HydrophobicContact CE1-CD1 4.23Å; F190-F199 HydrophobicContact CE2-CB 4.27Å; F190-F199 HydrophobicContact CG-CB 4.13Å; F190-F199 HydrophobicContact CZ-CB 4.26Å; F190-F199 HydrophobicContact CZ-CD1 4.23Å; F190-F199 HydrophobicContact CZ-CG 4.45Å
191L96.8Very high95.8Very high33 Ų3351 Ų5117%0.17329%0.287CS..EExtended strand (participates in β ladder)trans-147.5164175.762.895000110Q193 C198 Y200 E208 P211L191-Q193 HydrophobicContact CD1-CG 3.47Å; L191-Q193 VanDerWaalsContact CD1-CG 3.47Å; L191-C198 HydrophobicContact CD1-CB 3.97Å; L191-C198 HydrophobicContact CG-CB 4.25Å; L191-C198 PolarHBondContact N-O 2.87Å; L191-C198 PolarHBondContact O-N 3.03Å; L191-C198 VanDerWaalsContact O-O 3.11Å; L191-Y200 HydrophobicContact CD2-CD1 3.77Å; L191-Y200 HydrophobicContact CD2-CE1 4.23Å; L191-E208 HydrophobicContact CD2-CG 3.67Å; L191-P211 HydrophobicContact CD1-CG 4.27Å; L191-P211 HydrophobicContact CD2-CB 4.34Å
192M95.9Very high95.4Very high111 Ų11153.8 Ų53.855%0.54730%0.296SS..EExtended strand (participates in β ladder)trans-105.3130.3174.4-66.6-62.2-62.100109.4N196M192-N196 WeakPolarHBondContact CA-O 3.3Å
193Q94.3Very high95.1Very high90 Ų9054.6 Ų54.642%0.42130%0.3SS..EExtended strand (participates in β ladder)trans-116.3104.4166-66.9-167.8-10.300108.9L191 N195 N196 P211L191-Q193 HydrophobicContact CD1-CG 3.47Å; L191-Q193 VanDerWaalsContact CD1-CG 3.47Å; Q193-N195 PolarHBondContact O-N 3.39Å; Q193-N196 PolarHBondContact N-O 2.86Å; Q193-N196 WeakPolarHBondContact O-CB 3.13Å; Q193-N196 PolarHBondContact O-N 3.17Å; Q193-P211 VanDerWaalsContact NE2-CG 3.3Å
194G92.8Very high94.6Very high69 Ų6960.8 Ų60.871%0.71132%0.319SS*.THydrogen-bonded Turntrans60.2-121.9-169.300000110.7
195N93.5Very high94.1Very high148 Ų14860 Ų6079%0.79131%0.307SS*.THydrogen-bonded Turntrans-92.10.4177.9-67.3-14000113.6Q193Q193-N195 PolarHBondContact O-N 3.39Å
196N96.9Very high94Very high53 Ų5357.1 Ų57.128%0.28330%0.296SS..EExtended strand (participates in β ladder)trans-97.4132.8-174-66.3-21000111.4M192 Q193 C213 A214 G216M192-N196 WeakPolarHBondContact CA-O 3.3Å; Q193-N196 PolarHBondContact N-O 2.86Å; Q193-N196 WeakPolarHBondContact O-CB 3.13Å; Q193-N196 PolarHBondContact O-N 3.17Å; N196-C213 HydrophobicContact CB-CB 4.38Å; N196-A214 VanDerWaalsContact CB-O 3.26Å; N196-A214 WeakPolarHBondContact CB-O 3.16Å; N196-A214 PolarHBondContact ND2-O 3.35Å; N196-A214 PolarHBondContact OD1-O 3.19Å; N196-G216 WeakPolarHBondContact CA-O 3.31Å; N196-G216 PolarHBondContact OD1-N 3.28Å
197T97.1Very high93.9Very high5 Ų564.3 Ų64.33%0.03132%0.323CS..EExtended strand (participates in β ladder)trans-78.9125.8168.5-61.90000109.2L174 F190 A214 G216L174-T197 HydrophobicContact CB-CG2 4.08Å; L174-T197 HydrophobicContact CD1-CG2 3.84Å; F190-T197 HydrophobicContact CD1-CG2 3.64Å; F190-T197 HydrophobicContact CE1-CG2 3.81Å; T197-A214 WeakPolarHBondContact O-CB 3.36Å; T197-A214 PolarHBondContact O-N 3.46Å; T197-G216 PolarHBondContact N-O 3.2Å
198C97.3Very high93.7Very high0 Ų067.5 Ų67.50%034%0.336CS..EExtended strand (participates in β ladder)trans-127.5160.2-178.6-450000111.3F190 L191 P211 A212 C213F190-C198 VanDerWaalsContact CA-O 3.3Å; F190-C198 WeakPolarHBondContact CA-O 3.45Å; F190-C198 WeakPolarHBondContact CD1-O 2.94Å; L191-C198 HydrophobicContact CD1-CB 3.97Å; L191-C198 HydrophobicContact CG-CB 4.25Å; L191-C198 PolarHBondContact N-O 2.87Å; L191-C198 PolarHBondContact O-N 3.03Å; L191-C198 VanDerWaalsContact O-O 3.11Å; C198-P211 HydrophobicContact CB-CB 3.93Å; C198-P211 HydrophobicContact CB-CG 4.17Å; C198-A212 CarbonylContact C-O 3.47Å; C198-A212 WeakPolarHBondContact CA-O 3.46Å; C198-A212 WeakPolarHBondContact CB-O 3Å; C198-C213 HydrophobicContact CB-CB 3.98Å; C198-C213 WeakPolarHBondContact CB-SG 3.04Å; C198-C213 VanDerWaalsContact SG-CA 3.54Å; C198-C213 WeakPolarHBondContact SG-CB 2.94Å; C198-C213 CovalentContact SG-SG 2.04Å; C198-C213 PolarHBondContact SG-SG 3.5Å
199F96.9Very high93.6Very high5 Ų569.4 Ų69.42%0.02235%0.345CS..EExtended strand (participates in β ladder)trans-144.7147.3165.570.9-86.6000110.8L108 F122 P124 L174 L186 T189 F190 A212 M219L108-F199 HydrophobicContact CD1-CD2 4.09Å; L108-F199 HydrophobicContact CD1-CE2 3.73Å; L108-F199 HydrophobicContact CD2-CD2 4.49Å; L108-F199 HydrophobicContact CD2-CE2 4.2Å; L108-F199 HydrophobicContact CG-CE2 4.18Å; F122-F199 HydrophobicContact CE1-CZ 4.44Å; P124-F199 HydrophobicContact CB-CZ 4.36Å; P124-F199 HydrophobicContact CG-CZ 4.16Å; L174-F199 HydrophobicContact CD1-CD1 4.42Å; L174-F199 HydrophobicContact CD2-CE1 4.29Å; L186-F199 HydrophobicContact CD1-CD2 4.12Å; L186-F199 HydrophobicContact CD1-CE2 4.5Å; T189-F199 WeakPolarHBondContact O-CA 3.16Å; F190-F199 HydrophobicContact CD1-CB 4.1Å; F190-F199 HydrophobicContact CD2-CB 4.19Å; F190-F199 HydrophobicContact CE1-CB 4.17Å; F190-F199 HydrophobicContact CE1-CD1 4.23Å; F190-F199 HydrophobicContact CE2-CB 4.27Å; F190-F199 HydrophobicContact CG-CB 4.13Å; F190-F199 HydrophobicContact CZ-CB 4.26Å; F190-F199 HydrophobicContact CZ-CD1 4.23Å; F190-F199 HydrophobicContact CZ-CG 4.45Å; F199-A212 PolarHBondContact N-O 2.98Å; F199-A212 PolarHBondContact O-N 2.75Å; F199-M219 HydrophobicContact CD1-CE 4.16Å; F199-M219 HydrophobicContact CD1-SD 4.34Å; F199-M219 HydrophobicContact CE1-CE 3.84Å; F199-M219 HydrophobicContact CE1-SD 3.48Å; F199-M219 WeakPolarHBondContact CE1-SD 3.4Å; F199-M219 HydrophobicContact CZ-SD 4.21Å
200Y94.5Very high93.5Very high50 Ų5073 Ų7320%0.19636%0.361CS..  trans-106-9.9176.364.3-91.9000113.4L108 T189 L191 C206 R207 E208L108-Y200 VanDerWaalsContact CD1-O 3.27Å; L108-Y200 WeakPolarHBondContact CD1-O 3.47Å; T189-Y200 HydrophobicContact CG2-CD2 4.4Å; T189-Y200 HydrophobicContact CG2-CE1 4.44Å; T189-Y200 HydrophobicContact CG2-CE2 3.84Å; T189-Y200 WeakPolarHBondContact O-CD1 3.14Å; T189-Y200 VanDerWaalsContact O-CE1 3.28Å; T189-Y200 WeakPolarHBondContact O-CE1 3.29Å; T189-Y200 PolarHBondContact O-N 2.99Å; L191-Y200 HydrophobicContact CD2-CD1 3.77Å; L191-Y200 HydrophobicContact CD2-CE1 4.23Å; Y200-C206 VanDerWaalsContact O-CB 3.24Å; Y200-C206 WeakPolarHBondContact O-CB 3.44Å; Y200-C206 PolarHBondContact O-SG 3.13Å; Y200-R207 VanDerWaalsContact CB-O 3.24Å; Y200-R207 WeakPolarHBondContact CB-O 3.21Å; Y200-E208 HydrophobicContact CD1-CB 4.19Å; Y200-E208 HydrophobicContact CD1-CG 4.23Å; Y200-E208 HydrophobicContact CE1-CB 4.14Å; Y200-E208 HydrophobicContact CE1-CG 4.07Å
201G92.9Very high93.4Very high1 Ų172 Ų721%0.0136%0.359CS..  trans60.2-160.6177.300000114T189T189-G201 WeakPolarHBondContact CG2-O 3.4Å; T189-G201 PolarHBondContact OG1-N 2.97Å
202K90.3Very high93.4Very high97 Ų9770.5 Ų70.542%0.42235%0.351SS..SBendtrans-133.5112.6176.2-65.9-170.4-174.6-178.30110.4V101 Q185 T189V101-K202 HydrophobicContact CB-CB 4.4Å; V101-K202 HydrophobicContact CG1-CB 4.26Å; V101-K202 HydrophobicContact CG1-CG 4.35Å; V101-K202 HydrophobicContact CG2-CB 4.41Å; Q185-K202 HydrophobicContact CG-CD 3.75Å; T189-K202 HydrophobicContact CG2-CG 4.07Å
203C90.1Very high93.4Very high33 Ų3367.3 Ų67.322%0.22334%0.339CS..SBendtrans-158.4173.3178.375.70000110T106 Y205 C206T106-C203 PolarHBondContact O-SG 2.95Å; C203-Y205 VanDerWaalsContact C-N 3.33Å; C203-Y205 PolarHBondContact O-N 2.89Å; C203-C206 HydrophobicContact CB-CB 4.04Å; C203-C206 WeakPolarHBondContact CB-SG 3.33Å; C203-C206 PolarHBondContact N-SG 2.92Å; C203-C206 VanDerWaalsContact N-SG 3.42Å; C203-C206 PolarHBondContact O-N 3.32Å; C203-C206 VanDerWaalsContact SG-CA 3.59Å; C203-C206 WeakPolarHBondContact SG-CB 3.16Å; C203-C206 PolarHBondContact SG-N 3.06Å; C203-C206 CovalentContact SG-SG 2.03Å; C203-C206 PolarHBondContact SG-SG 2.76Å
204Y86.9Confident93.6Very high181 Ų18163.2 Ų63.271%0.7132%0.321SS*.THydrogen-bonded Turntrans-60.2-37.2-175.3-174.7-99.7000113.9G105G105-Y204 PolarHBondContact O-N 3.33Å; G105-Y204 VanDerWaalsContact O-N 3.08Å
205Y86.5Confident93.7Very high121 Ų12166.5 Ų66.548%0.47532%0.322SS..THydrogen-bonded Turntrans-1036.3177.4-59.7-57.4000114T106 C203 R207T106-Y205 HydrophobicContact CG2-CD2 4.39Å; T106-Y205 HydrophobicContact CG2-CE2 3.93Å; T106-Y205 WeakPolarHBondContact O-CB 3.47Å; T106-Y205 VanDerWaalsContact O-CD2 3.23Å; T106-Y205 WeakPolarHBondContact O-CD2 3.44Å; T106-Y205 PolarHBondContact O-N 2.86Å; C203-Y205 VanDerWaalsContact C-N 3.33Å; C203-Y205 PolarHBondContact O-N 2.89Å; Y205-R207 PolarHBondContact O-N 3.05Å
206C91.3Very high93.8Very high28 Ų2860.5 Ų60.519%0.18930%0.295CS..  trans-76.1125.8-177.1-73.60000110.6Y200 C203Y200-C206 VanDerWaalsContact O-CB 3.24Å; Y200-C206 WeakPolarHBondContact O-CB 3.44Å; Y200-C206 PolarHBondContact O-SG 3.13Å; C203-C206 HydrophobicContact CB-CB 4.04Å; C203-C206 WeakPolarHBondContact CB-SG 3.33Å; C203-C206 PolarHBondContact N-SG 2.92Å; C203-C206 VanDerWaalsContact N-SG 3.42Å; C203-C206 PolarHBondContact O-N 3.32Å; C203-C206 VanDerWaalsContact SG-CA 3.59Å; C203-C206 WeakPolarHBondContact SG-CB 3.16Å; C203-C206 PolarHBondContact SG-N 3.06Å; C203-C206 CovalentContact SG-SG 2.03Å; C203-C206 PolarHBondContact SG-SG 2.76Å
207R92.2Very high93.8Very high153 Ų15361 Ų6158%0.57730%0.296SS*.  trans-137.2148.7-179.4-59.3179.2-175.1-1531.2110.1Y200 Y205 T209 E210Y200-R207 VanDerWaalsContact CB-O 3.24Å; Y200-R207 WeakPolarHBondContact CB-O 3.21Å; Y205-R207 PolarHBondContact O-N 3.05Å; R207-T209 PolarHBondContact O-N 2.91Å; R207-E210 CarbonylContact O-C 3.59Å; R207-E210 PolarHBondContact O-N 3.29Å
208E92.6Very high93.9Very high131 Ų13163.7 Ų63.761%0.61231%0.312SS*.THydrogen-bonded Turntrans-59.7-26.6175.5-168178.2171.300112.8L191 Y200 E210 P211L191-E208 HydrophobicContact CD2-CG 3.67Å; Y200-E208 HydrophobicContact CD1-CB 4.19Å; Y200-E208 HydrophobicContact CD1-CG 4.23Å; Y200-E208 HydrophobicContact CE1-CB 4.14Å; Y200-E208 HydrophobicContact CE1-CG 4.07Å; E208-E210 VanDerWaalsContact C-N 3.29Å; E208-E210 PolarHBondContact O-N 2.97Å; E208-P211 WeakPolarHBondContact O-CD 3.06Å
209T93.6Very high93.9Very high113 Ų11363.8 Ų63.869%0.69331%0.313SS*.THydrogen-bonded Turntrans-73.8-16.4176.154.80000113.9R207R207-T209 PolarHBondContact O-N 2.91Å
210E93.1Very high94Very high74 Ų7464.6 Ų64.635%0.34632%0.317SS..SBendtrans-127.751.6-173.5-63.7176.9129.600112.3R126 Y141 R207 E208R126-E210 PolarHBondContact NH2-O 3.34Å; Y141-E210 WeakPolarHBondContact OH-CG 3.02Å; Y141-E210 PolarHBondContact OH-OE1 2.86Å; R207-E210 CarbonylContact O-C 3.59Å; R207-E210 PolarHBondContact O-N 3.29Å; E208-E210 VanDerWaalsContact C-N 3.29Å; E208-E210 PolarHBondContact O-N 2.97Å
211P95.3Very high94.1Very high17 Ų1762.2 Ų62.211%0.1131%0.307CS..  trans-74165.2-177.234.9-35.8000112L191 Q193 C198 E208L191-P211 HydrophobicContact CD1-CG 4.27Å; L191-P211 HydrophobicContact CD2-CB 4.34Å; Q193-P211 VanDerWaalsContact NE2-CG 3.3Å; C198-P211 HydrophobicContact CB-CB 3.93Å; C198-P211 HydrophobicContact CB-CG 4.17Å; E208-P211 WeakPolarHBondContact O-CD 3.06Å
212A96.7Very high94.4Very high1 Ų162.2 Ų62.21%0.00831%0.307CS..EExtended strand (participates in β ladder)trans-91.8129.7160.200000108.9L108 P124 C198 F199 M219L108-A212 HydrophobicContact CD2-CB 3.65Å; P124-A212 HydrophobicContact CB-CB 3.81Å; P124-A212 HydrophobicContact CG-CB 3.61Å; C198-A212 CarbonylContact C-O 3.47Å; C198-A212 WeakPolarHBondContact CA-O 3.46Å; C198-A212 WeakPolarHBondContact CB-O 3Å; F199-A212 PolarHBondContact N-O 2.98Å; F199-A212 PolarHBondContact O-N 2.75Å; A212-M219 HydrophobicContact CB-CE 3.97Å; A212-M219 WeakPolarHBondContact O-CE 3.49Å
213C96.8Very high94.7Very high44 Ų4457.6 Ų57.630%0.29729%0.287SS..EExtended strand (participates in β ladder)trans-113.8138.8-177.1-69.40000111.6N196 C198 M219N196-C213 HydrophobicContact CB-CB 4.38Å; C198-C213 HydrophobicContact CB-CB 3.98Å; C198-C213 WeakPolarHBondContact CB-SG 3.04Å; C198-C213 VanDerWaalsContact SG-CA 3.54Å; C198-C213 WeakPolarHBondContact SG-CB 2.94Å; C198-C213 CovalentContact SG-SG 2.04Å; C198-C213 PolarHBondContact SG-SG 3.5Å; C213-M219 VanDerWaalsContact C-CE 3.45Å
214A97.2Very high95.1Very high4 Ų456.8 Ų56.83%0.03328%0.281CS..  trans-73.5164.6168.300000111.2L174 N196 T197 T218 M219L174-A214 HydrophobicContact CD1-CB 3.78Å; L174-A214 HydrophobicContact CG-CB 4.4Å; N196-A214 VanDerWaalsContact CB-O 3.26Å; N196-A214 WeakPolarHBondContact CB-O 3.16Å; N196-A214 PolarHBondContact ND2-O 3.35Å; N196-A214 PolarHBondContact OD1-O 3.19Å; T197-A214 WeakPolarHBondContact O-CB 3.36Å; T197-A214 PolarHBondContact O-N 3.46Å; A214-T218 WeakPolarHBondContact CB-O 3.3Å; A214-M219 HydrophobicContact CB-CB 4.01Å; A214-M219 HydrophobicContact CB-CE 4.43Å
215D96.5Very high95.5Very high138 Ų13849 Ų4974%0.73825%0.252SS*.BIsolated β-bridgetrans-86.4103.5159.5-171.79000108E217 T218D215-E217 PolarHBondContact O-N 3.48Å; D215-T218 PolarHBondContact N-O 2.04Å; D215-T218 PolarHBondContact O-N 3.4Å
216G96Very high95.9Very high22 Ų2248.7 Ų48.723%0.22725%0.25CC..THydrogen-bonded Turntrans61.5-100.3-163.900000111.6N196 T197N196-G216 WeakPolarHBondContact CA-O 3.31Å; N196-G216 PolarHBondContact OD1-N 3.28Å; T197-G216 PolarHBondContact N-O 3.2Å
217E96.5Very high96Very high63 Ų6348.3 Ų48.329%0.29425%0.246SC..THydrogen-bonded Turntrans-113.8-10.1178.3-62-177.9167.300113N173 L174 R175 D215N173-E217 WeakPolarHBondContact CA-O 3.09Å; L174-E217 PolarHBondContact N-O 3.28Å; R175-E217 HydrophobicContact CB-CG 4.42Å; R175-E217 VanDerWaalsContact CD-CD 3.44Å; R175-E217 WeakPolarHBondContact CD-OE1 3.12Å; R175-E217 WeakPolarHBondContact CD-OE2 3.49Å; R175-E217 IonicContact CZ-OE1 2.81Å; R175-E217 IonicContact NE-OE1 3.96Å; R175-E217 IonicContact NH1-OE1 3.82Å; R175-E217 PolarHBondContact NH1-OE1 3.1Å; D215-E217 PolarHBondContact O-N 3.48Å
218T97.9Very high96.1Very high61 Ų6142.1 Ų42.137%0.37423%0.226SC..EExtended strand (participates in β ladder)trans-96.7117.7-175.1-55.90000110.6Y171 A214 D215Y171-T218 HydrophobicContact CD1-CG2 4.12Å; Y171-T218 HydrophobicContact CG-CG2 4.45Å; A214-T218 WeakPolarHBondContact CB-O 3.3Å; D215-T218 PolarHBondContact N-O 2.04Å; D215-T218 PolarHBondContact O-N 3.4Å
219M97.9Very high96Very high2 Ų242 Ų421%0.0123%0.229CC..EExtended strand (participates in β ladder)trans-107.3124.8178.7-176.2169.5-83.600110.9F122 P124 Y171 V172 L174 F199 A212 C213 A214F122-M219 HydrophobicContact CE1-CG 4.47Å; F122-M219 HydrophobicContact CE1-SD 3.93Å; F122-M219 HydrophobicContact CZ-CG 4.13Å; F122-M219 HydrophobicContact CZ-SD 4.19Å; P124-M219 HydrophobicContact CB-CE 4.37Å; P124-M219 HydrophobicContact CB-CG 4.28Å; P124-M219 HydrophobicContact CB-SD 3.43Å; P124-M219 WeakPolarHBondContact CB-SD 3.38Å; Y171-M219 WeakPolarHBondContact CA-O 3.29Å; V172-M219 PolarHBondContact N-O 3.01Å; V172-M219 PolarHBondContact O-N 2.95Å; L174-M219 HydrophobicContact CD1-CB 4.16Å; L174-M219 HydrophobicContact CD1-CE 3.84Å; L174-M219 HydrophobicContact CD1-SD 4.3Å; L174-M219 HydrophobicContact CD2-CB 3.96Å; L174-M219 HydrophobicContact CD2-SD 4.13Å; L174-M219 HydrophobicContact CG-CB 3.96Å; F199-M219 HydrophobicContact CD1-CE 4.16Å; F199-M219 HydrophobicContact CD1-SD 4.34Å; F199-M219 HydrophobicContact CE1-CE 3.84Å; F199-M219 HydrophobicContact CE1-SD 3.48Å; F199-M219 WeakPolarHBondContact CE1-SD 3.4Å; F199-M219 HydrophobicContact CZ-SD 4.21Å; A212-M219 HydrophobicContact CB-CE 3.97Å; A212-M219 WeakPolarHBondContact O-CE 3.49Å; C213-M219 VanDerWaalsContact C-CE 3.45Å; A214-M219 HydrophobicContact CB-CB 4.01Å; A214-M219 HydrophobicContact CB-CE 4.43Å
220E98.3Very high95.8Very high23 Ų2342 Ų4211%0.10723%0.229CC..EExtended strand (participates in β ladder)trans-78.9140.3168.1-166.8-17112900110.3K125 R129 H144 Y171 I365K125-E220 HydrophobicContact CB-CB 4.17Å; K125-E220 VanDerWaalsContact CB-O 3.25Å; K125-E220 WeakPolarHBondContact CB-O 3.18Å; K125-E220 HydrophobicContact CD-CB 4.17Å; K125-E220 PolarHBondContact N-O 2.92Å; K125-E220 IonicContact NZ-OE2 3.75Å; R129-E220 IonicContact CZ-OE1 3.39Å; R129-E220 IonicContact NH1-OE1 3.65Å; R129-E220 PolarHBondContact NH1-OE1 2.94Å; R129-E220 IonicContact NH2-OE1 2.72Å; R129-E220 PolarHBondContact NH2-OE1 3.01Å; H144-E220 IonicContact CD2-OE1 3.21Å; H144-E220 IonicContact CE1-OE1 2.68Å; H144-E220 PolarHBondContact CE1-OE1 3.38Å; H144-E220 IonicContact NE2-OE1 3.54Å; H144-E220 PolarHBondContact NE2-OE1 3.25Å; Y171-E220 HydrophobicContact CD1-CB 3.88Å; Y171-E220 HydrophobicContact CD1-CG 4.06Å; Y171-E220 HydrophobicContact CE1-CB 3.69Å; Y171-E220 HydrophobicContact CE1-CG 3.58Å; E220-I365 HydrophobicContact CG-CB 4.28Å; E220-I365 HydrophobicContact CG-CG2 3.8Å
221G97.9Very high95.7Very high0 Ų041.5 Ų41.50%022%0.224CC..EExtended strand (participates in β ladder)trans-164.7-176.6173.400000112.7K123 G169 R170K123-G221 CarbonylContact O-C 3.57Å; K123-G221 VanDerWaalsContact O-CA 3.23Å; K123-G221 WeakPolarHBondContact O-CA 3.4Å; G169-G221 WeakPolarHBondContact CA-O 3.48Å; R170-G221 PolarHBondContact N-O 3.4Å; R170-G221 PolarHBondContact O-N 3.23Å
222S98.1Very high95.5Very high0 Ų043.4 Ų43.40%024%0.236CC..EExtended strand (participates in β ladder)trans-111.3139.1175.5600000109.8F122 K123 H144 V168F122-S222 WeakPolarHBondContact CA-O 3.23Å; K123-S222 PolarHBondContact N-O 3.41Å; K123-S222 PolarHBondContact O-N 2.86Å; H144-S222 WeakPolarHBondContact CB-OG 3.28Å; H144-S222 WeakPolarHBondContact O-CB 3.45Å; V168-S222 WeakPolarHBondContact O-CA 3.14Å
223L97.8Very high95.3Very high0 Ų046.2 Ų46.20%025%0.251CS..EExtended strand (participates in β ladder)trans-107.9120.4171.6-70.2177.6000109.2L91 L112 V120 V121 F122 V167 V168 R170L91-L223 HydrophobicContact CD1-CB 4.5Å; L91-L223 HydrophobicContact CD2-CB 4.44Å; L91-L223 HydrophobicContact CG-CB 4.2Å; L91-L223 VanDerWaalsContact O-CD1 3.26Å; L91-L223 WeakPolarHBondContact O-CD1 3.45Å; L112-L223 HydrophobicContact CD1-CD2 3.85Å; V120-L223 HydrophobicContact CB-CD2 4.46Å; V120-L223 HydrophobicContact CG2-CD2 3.79Å; V121-L223 CarbonylContact O-C 3.31Å; V121-L223 WeakPolarHBondContact O-CA 3.25Å; F122-L223 HydrophobicContact CB-CD2 3.88Å; F122-L223 HydrophobicContact CD2-CD2 3.71Å; F122-L223 HydrophobicContact CD2-CG 4.34Å; F122-L223 HydrophobicContact CG-CD2 4.26Å; V167-L223 CarbonylContact C-O 3.59Å; V167-L223 VanDerWaalsContact CA-O 3.26Å; V167-L223 WeakPolarHBondContact CA-O 3.3Å; V168-L223 HydrophobicContact CG1-CB 4.21Å; V168-L223 PolarHBondContact N-O 2.89Å; V168-L223 PolarHBondContact O-N 2.97Å; R170-L223 HydrophobicContact CB-CD1 4.01Å; R170-L223 HydrophobicContact CB-CG 4.32Å; R170-L223 HydrophobicContact CG-CD1 4.35Å
224T96.9Very high95.1Very high17 Ų1748.4 Ų48.410%0.10426%0.257CS..EExtended strand (participates in β ladder)trans-104.7124.7173.2-54.70000109.4V120 V121 P165 L166 V167 W226V120-T224 CarbonylContact C-O 3.53Å; V120-T224 VanDerWaalsContact CA-O 3.24Å; V120-T224 WeakPolarHBondContact CA-O 3.26Å; V120-T224 WeakPolarHBondContact CB-O 3.41Å; V121-T224 PolarHBondContact N-O 2.87Å; V121-T224 PolarHBondContact O-N 3.39Å; P165-T224 HydrophobicContact CB-CG2 3.82Å; P165-T224 HydrophobicContact CG-CG2 3.44Å; P165-T224 VanDerWaalsContact CG-CG2 3.44Å; L166-T224 WeakPolarHBondContact O-CA 3.24Å; V167-T224 HydrophobicContact CG2-CG2 4.01Å; T224-W226 PolarHBondContact O-N 2.93Å
225L96.3Very high94.8Very high18 Ų1854.4 Ų54.49%0.09428%0.282CS..EExtended strand (participates in β ladder)trans-66.4130.2177.3-17367000110.4W64 A67 L91 Q118 V120 L166W64-L225 HydrophobicContact CE3-CD1 4.36Å; A67-L225 HydrophobicContact CB-CD2 3.82Å; L91-L225 HydrophobicContact CD1-CD1 4.25Å; Q118-L225 HydrophobicContact CG-CD1 3.47Å; Q118-L225 VanDerWaalsContact CG-CD1 3.47Å; V120-L225 HydrophobicContact CG1-CD1 4.2Å; L166-L225 HydrophobicContact CB-CB 4.12Å; L166-L225 HydrophobicContact CB-CD2 4.41Å; L166-L225 HydrophobicContact CD1-CD2 3.95Å; L166-L225 HydrophobicContact CG-CD2 4.38Å; L166-L225 PolarHBondContact O-N 3.04Å
226W95Very high94.6Very high114 Ų11449.3 Ų49.343%0.43225%0.254SS..PPolyproline II helixtrans-69.8133.4175.3-158.4-91.1000110.3L111 Q118 K119 V121 T224L111-W226 HydrophobicContact CD1-CE3 4.38Å; L111-W226 HydrophobicContact CD1-CZ3 4.39Å; Q118-W226 PolarHBondContact NE2-O 2.62Å; K119-W226 HydrophobicContact CB-CB 3.73Å; K119-W226 HydrophobicContact CB-CD2 4.48Å; K119-W226 HydrophobicContact CB-CG 4.02Å; K119-W226 WeakPolarHBondContact O-CB 3.4Å; K119-W226 PolarHBondContact O-N 3.23Å; K119-W226 VanDerWaalsContact O-N 3.09Å; V121-W226 HydrophobicContact CG2-CE3 3.62Å; V121-W226 HydrophobicContact CG2-CZ3 3.48Å; V121-W226 VanDerWaalsContact CG2-CZ3 3.48Å; T224-W226 PolarHBondContact O-N 2.93Å
227L94.1Very high94.5Very high19 Ų1957.4 Ų57.410%0.09928%0.277CS..PPolyproline II helixtrans-67144.2176.1-67.6173.4000110.2V71 V76 P165 L233 F298 I308V71-L227 HydrophobicContact CG2-CD2 4.4Å; V76-L227 HydrophobicContact CG1-CD2 3.96Å; P165-L227 HydrophobicContact CB-CD2 4.42Å; L227-L233 HydrophobicContact CD1-CD1 4.34Å; L227-L233 HydrophobicContact CD1-CD2 4.1Å; L227-F298 HydrophobicContact CD1-CE1 4Å; L227-F298 HydrophobicContact CD1-CZ 4.28Å; L227-I308 HydrophobicContact CD1-CG2 4.05Å
228P92.8Very high94.5Very high24 Ų2455 Ų5516%0.15627%0.266CS..PPolyproline II helixtrans-64.2144.2-175.729.2-39.9000112.6S68 V71 V230 W231S68-P228 VanDerWaalsContact OG-CB 3.25Å; S68-P228 WeakPolarHBondContact OG-CB 3.45Å; V71-P228 HydrophobicContact CB-CG 4.2Å; V71-P228 HydrophobicContact CG2-CG 4.02Å; P228-V230 HydrophobicContact CB-CG2 4.26Å; P228-V230 HydrophobicContact CG-CG2 4.4Å; P228-V230 PolarHBondContact O-N 3.42Å; P228-W231 PolarHBondContact O-N 3.47Å
229D90.9Very high94.4Very high128 Ų12853 Ų5368%0.68425%0.254SS*.THydrogen-bonded Turntrans-62.4-20.8-172.8-67.9-28.7000113.7W231D229-W231 PolarHBondContact O-N 3.09Å
230V90.8Very high94.4Very high114 Ų11453.6 Ų53.669%0.69126%0.256SS*.THydrogen-bonded Turntrans-67.3-16175.1-57.30000113.1P228 P232P228-V230 HydrophobicContact CB-CG2 4.26Å; P228-V230 HydrophobicContact CG-CG2 4.4Å; P228-V230 PolarHBondContact O-N 3.42Å; V230-P232 WeakPolarHBondContact O-CD 3.5Å
231W90.7Very high94.2Very high62 Ų6253 Ų5324%0.23526%0.257CS..SBendtrans-112.870.3178.3-71.2113.4000110.6V71 P73 P228 D229 F298V71-W231 HydrophobicContact CG1-CB 4.4Å; V71-W231 HydrophobicContact CG1-CD2 4.32Å; V71-W231 HydrophobicContact CG1-CG 3.82Å; V71-W231 PolarHBondContact O-NE1 3.37Å; P73-W231 HydrophobicContact CG-CH2 3.61Å; P73-W231 HydrophobicContact CG-CZ3 4.05Å; P228-W231 PolarHBondContact O-N 3.47Å; D229-W231 PolarHBondContact O-N 3.09Å; W231-F298 HydrophobicContact CB-CD1 3.61Å; W231-F298 HydrophobicContact CB-CE1 3.58Å; W231-F298 HydrophobicContact CB-CG 4.35Å; W231-F298 HydrophobicContact CB-CZ 4.3Å; W231-F298 HydrophobicContact CD2-CG 4.47Å; W231-F298 HydrophobicContact CE3-CB 3.99Å; W231-F298 HydrophobicContact CE3-CD1 4.3Å; W231-F298 HydrophobicContact CE3-CD2 4.09Å; W231-F298 AromaticContact CE3-CG 3.87Å; W231-F298 HydrophobicContact CE3-CG 3.87Å; W231-F298 HydrophobicContact CG-CD1 4.35Å; W231-F298 HydrophobicContact CG-CE1 4.27Å
232P91.4Very high94Very high58 Ų5855.1 Ų55.138%0.37727%0.265SS..  trans-64.7140.1-177.725.8-32.4000111.2V230 Q299V230-P232 WeakPolarHBondContact O-CD 3.5Å; P232-Q299 HydrophobicContact CG-CB 4.16Å; P232-Q299 HydrophobicContact CG-CG 4.45Å; P232-Q299 PolarHBondContact O-N 3.25Å
233L91.9Very high93.6Very high60 Ų6057.1 Ų57.131%0.31428%0.277SS..EExtended strand (participates in β ladder)trans-88.2141.6-176.9-61.2167.8000111L227 E296 S297 F298 Q299 I308 L310L227-L233 HydrophobicContact CD1-CD1 4.34Å; L227-L233 HydrophobicContact CD1-CD2 4.1Å; L233-E296 HydrophobicContact CB-CB 4.5Å; L233-E296 VanDerWaalsContact CD1-OE2 3.3Å; L233-E296 WeakPolarHBondContact CD1-OE2 3.44Å; L233-S297 CarbonylContact C-O 3.52Å; L233-F298 HydrophobicContact CD2-CD1 3.76Å; L233-F298 HydrophobicContact CD2-CE1 3.8Å; L233-Q299 PolarHBondContact O-NE2 2.8Å; L233-Q299 VanDerWaalsContact O-NE2 3.1Å; L233-I308 HydrophobicContact CD2-CG1 4.15Å; L233-L310 HydrophobicContact CD1-CD1 3.81Å
234Q91.4Very high93.1Very high90 Ų9060.6 Ų60.642%0.42129%0.291SS..EExtended strand (participates in β ladder)trans-112.7126.6170.6-166.5179.518.300109H236 E296 S297 Q299Q234-H236 VanDerWaalsContact CD-CE1 3.45Å; Q234-H236 PolarHBondContact O-CD2 3.35Å; Q234-H236 VanDerWaalsContact O-CD2 3.27Å; Q234-H236 PolarHBondContact OE1-CE1 3.43Å; Q234-H236 PolarHBondContact OE1-NE2 3.44Å; Q234-E296 CarbonylContact O-C 3.5Å; Q234-E296 VanDerWaalsContact O-CA 3.24Å; Q234-E296 WeakPolarHBondContact O-CA 3.41Å; Q234-S297 PolarHBondContact N-O 3.35Å; Q234-S297 PolarHBondContact O-N 2.87Å; Q234-Q299 HydrophobicContact CB-CG 3.75Å; Q234-Q299 HydrophobicContact CG-CG 4.48Å
235K91.8Very high92.7Very high130 Ų13067.9 Ų67.957%0.56532%0.316SS*.EExtended strand (participates in β ladder)trans-90.2130.3178.4-174.6171.7-178.8167.40111.1H294 E296K235-H294 HydrophobicContact CD-CB 4.46Å; K235-H294 VanDerWaalsContact CE-CB 3.49Å; K235-H294 WeakPolarHBondContact CE-CD2 3.37Å; K235-H294 HydrophobicContact CG-CB 4.14Å; K235-E296 HydrophobicContact CB-CG 4.46Å
236H92.7Very high92.1Very high30 Ų3076.7 Ų76.714%0.13936%0.357CS..EExtended strand (participates in β ladder)trans-122146.1178.9-61.2-86.8000110.4Q234 H294 Y295 S297Q234-H236 VanDerWaalsContact CD-CE1 3.45Å; Q234-H236 PolarHBondContact O-CD2 3.35Å; Q234-H236 VanDerWaalsContact O-CD2 3.27Å; Q234-H236 PolarHBondContact OE1-CE1 3.43Å; Q234-H236 PolarHBondContact OE1-NE2 3.44Å; H236-H294 WeakPolarHBondContact O-CA 3.37Å; H236-H294 VanDerWaalsContact O-CB 3.28Å; H236-H294 WeakPolarHBondContact O-CB 3.44Å; H236-H294 PolarHBondContact O-CD2 2.57Å; H236-Y295 HydrophobicContact CB-CD1 4.3Å; H236-Y295 HydrophobicContact CB-CD2 3.91Å; H236-Y295 HydrophobicContact CB-CE1 3.84Å; H236-Y295 HydrophobicContact CB-CE2 3.33Å; H236-Y295 HydrophobicContact CB-CG 4.35Å; H236-Y295 AromaticContact CD2-CE2 3.5Å; H236-Y295 VanDerWaalsContact CD2-CE2 3.5Å; H236-Y295 WeakPolarHBondContact CD2-CE2 3.39Å; H236-Y295 AromaticContact CG-CE2 3.52Å; H236-Y295 AromaticContact CG-CZ 3.83Å; H236-Y295 PolarHBondContact N-O 2.7Å; H236-Y295 PolarHBondContact O-N 3Å; H236-S297 PolarHBondContact CD2-OG 3.35Å; H236-S297 PolarHBondContact NE2-OG 2.81Å
237R94.1Very high91.7Very high192 Ų19275.3 Ų75.373%0.72538%0.378SS*.EExtended strand (participates in β ladder)trans-78.3130.2172-172.8175-179.5-178-0.1109.5Y268R237-Y268 PolarHBondContact O-OH 2.66Å
238H95.6Very high91.5Very high12 Ų1280 Ų806%0.05640%0.398CS..  trans-70.8129.2178-160.5-75.7000110W240 G241 R292 H293 Y295H238-W240 VanDerWaalsContact C-N 3.3Å; H238-W240 PolarHBondContact ND1-N 2.97Å; H238-W240 VanDerWaalsContact ND1-N 3.17Å; H238-W240 PolarHBondContact O-N 3.43Å; H238-G241 PolarHBondContact O-N 3.22Å; H238-R292 WeakPolarHBondContact CB-O 3.34Å; H238-H293 WeakPolarHBondContact CB-O 3.09Å; H238-H293 PolarHBondContact N-O 3.37Å; H238-Y295 HydrophobicContact CB-CD1 4.34Å; H238-Y295 AromaticContact CD2-CD1 3.81Å
239P96.2Very high91.5Very high20 Ų2084 Ų8413%0.1342%0.417CS..THydrogen-bonded Turntrans-61.7-40.1-179.6-21.832.6000111.8G241 Y258 V262 Y268P239-G241 PolarHBondContact O-N 2.95Å; P239-Y258 HydrophobicContact CB-CE1 4.35Å; P239-Y258 PolarHBondContact O-OH 2.84Å; P239-V262 HydrophobicContact CB-CG1 4.26Å; P239-V262 HydrophobicContact CB-CG2 4.05Å; P239-V262 HydrophobicContact CG-CG1 4.27Å; P239-Y268 WeakPolarHBondContact CD-OH 3.41Å; P239-Y268 HydrophobicContact CG-CD2 4.26Å; P239-Y268 HydrophobicContact CG-CE1 3.92Å; P239-Y268 HydrophobicContact CG-CE2 3.52Å; P239-Y268 WeakPolarHBondContact CG-OH 3.43Å
240W97.2Very high91.7Very high15 Ų1578.3 Ų78.36%0.05739%0.388CS..THydrogen-bonded Turntrans-84.424.2172.1-65.8-96.8000114.2H238 W252 Y258 C259 V262 L274 V277 A328 P329H238-W240 VanDerWaalsContact C-N 3.3Å; H238-W240 PolarHBondContact ND1-N 2.97Å; H238-W240 VanDerWaalsContact ND1-N 3.17Å; H238-W240 PolarHBondContact O-N 3.43Å; W240-W252 VanDerWaalsContact C-NE1 3.31Å; W240-W252 HydrophobicContact CB-CD2 4.42Å; W240-W252 HydrophobicContact CB-CG 4.35Å; W240-W252 AromaticContact CD1-CD2 3.8Å; W240-W252 AromaticContact CD1-CG 3.6Å; W240-W252 HydrophobicContact CG-CB 4.4Å; W240-W252 HydrophobicContact CG-CG 4.24Å; W240-W252 PolarHBondContact O-NE1 3.33Å; W240-Y258 HydrophobicContact CD2-CE1 4.17Å; W240-Y258 AromaticContact CE2-CD1 3.81Å; W240-Y258 AromaticContact CE2-CE1 3.84Å; W240-Y258 HydrophobicContact CG-CE1 4.45Å; W240-Y258 HydrophobicContact CZ2-CD1 4.02Å; W240-Y258 HydrophobicContact CZ2-CE1 4.18Å; W240-Y258 AromaticContact NE1-CD1 3.65Å; W240-Y258 AromaticContact NE1-CE1 3.93Å; W240-C259 HydrophobicContact CZ2-CB 4.11Å; W240-V262 HydrophobicContact CH2-CB 4.07Å; W240-V262 HydrophobicContact CH2-CG1 3.82Å; W240-V262 HydrophobicContact CH2-CG2 4.01Å; W240-V262 HydrophobicContact CZ2-CG2 4.29Å; W240-V262 HydrophobicContact CZ3-CG1 4Å; W240-V262 HydrophobicContact CZ3-CG2 4.46Å; W240-L274 HydrophobicContact CH2-CD1 4.04Å; W240-L274 HydrophobicContact CZ3-CD1 4.2Å; W240-V277 HydrophobicContact CE3-CG1 4.02Å; W240-V277 HydrophobicContact CZ3-CG1 3.97Å; W240-A328 HydrophobicContact CG-CB 4.49Å; W240-P329 HydrophobicContact CB-CG 4.2Å; W240-P329 HydrophobicContact CD2-CB 4.11Å; W240-P329 HydrophobicContact CD2-CG 3.59Å; W240-P329 HydrophobicContact CE3-CB 4.09Å; W240-P329 HydrophobicContact CE3-CG 3.77Å; W240-P329 HydrophobicContact CG-CG 3.76Å; W240-P329 HydrophobicContact CH2-CB 4.36Å; W240-P329 HydrophobicContact CZ2-CB 4.35Å; W240-P329 HydrophobicContact CZ3-CB 4.23Å; W240-P329 HydrophobicContact CZ3-CG 4.4Å
241G94.8Very high91.9Very high11 Ų1179 Ų7911%0.11338%0.378CS..  trans-65.1137.1174.800000111.6H238 P239 W252H238-G241 PolarHBondContact O-N 3.22Å; P239-G241 PolarHBondContact O-N 2.95Å; G241-W252 PolarHBondContact O-NE1 3.16Å; G241-W252 VanDerWaalsContact O-NE1 3.12Å
242R93.6Very high92.2Very high44 Ų4476.6 Ų76.617%0.16637%0.369CS..  trans-70163.1174.2-64.8177-171.5-84.5-4111.4Y244 W252 A290 S325R242-Y244 HydrophobicContact CB-CD2 4.22Å; R242-Y244 HydrophobicContact CB-CE2 3.92Å; R242-Y244 WeakPolarHBondContact O-CD2 3.09Å; R242-Y244 WeakPolarHBondContact O-CE2 3.23Å; R242-W252 HydrophobicContact CG-CZ2 4.09Å; R242-A290 PolarHBondContact NE-O 3.39Å; R242-A290 VanDerWaalsContact NE-O 3.09Å; R242-S325 PolarHBondContact NH2-OG 2.88Å
243T89.6Confident92.3Very high42 Ų4277.2 Ų77.226%0.25837%0.367SS..  trans-83.2-22.8177.760.70000113.6R245 K248 A250T243-R245 PolarHBondContact O-N 3Å; T243-R245 PolarHBondContact OG1-N 3.29Å; T243-K248 WeakPolarHBondContact CB-O 3.37Å; T243-K248 HydrophobicContact CG2-CD 4.42Å; T243-K248 HydrophobicContact CG2-CG 4.2Å; T243-K248 WeakPolarHBondContact CG2-O 3.47Å; T243-K248 PolarHBondContact OG1-O 3.03Å; T243-A250 HydrophobicContact CG2-CB 3.91Å
244Y87.8Confident92.4Very high73 Ų7381.6 Ų81.629%0.28638%0.38SS..  trans53.628.2-173.3-57.5-88.7000113.5Y138 R242 D291 H293Y138-Y244 HydrophobicContact CD1-CD1 4.07Å; Y138-Y244 AromaticContact CD1-CE1 3.92Å; Y138-Y244 HydrophobicContact CD1-CE1 3.92Å; Y138-Y244 AromaticContact CD2-CD1 3.84Å; Y138-Y244 HydrophobicContact CD2-CD1 3.84Å; Y138-Y244 AromaticContact CD2-CE1 3.94Å; Y138-Y244 HydrophobicContact CD2-CE1 3.94Å; Y138-Y244 HydrophobicContact CE1-CD1 4.02Å; Y138-Y244 HydrophobicContact CE1-CE1 4.33Å; Y138-Y244 AromaticContact CE2-CD1 3.79Å; Y138-Y244 HydrophobicContact CE2-CD1 3.79Å; Y138-Y244 HydrophobicContact CE2-CE1 4.35Å; Y138-Y244 AromaticContact CG-CD1 3.98Å; Y138-Y244 HydrophobicContact CG-CD1 3.98Å; Y138-Y244 AromaticContact CG-CE1 3.71Å; Y138-Y244 HydrophobicContact CG-CE1 3.71Å; Y138-Y244 AromaticContact CZ-CD1 3.87Å; R242-Y244 HydrophobicContact CB-CD2 4.22Å; R242-Y244 HydrophobicContact CB-CE2 3.92Å; R242-Y244 WeakPolarHBondContact O-CD2 3.09Å; R242-Y244 WeakPolarHBondContact O-CE2 3.23Å; Y244-D291 WeakPolarHBondContact CE1-OD1 3.4Å; Y244-D291 PolarHBondContact OH-O 3.07Å; Y244-D291 PolarHBondContact OH-OD1 3.27Å; Y244-H293 HydrophobicContact CE2-CB 3.58Å; Y244-H293 AromaticContact CE2-CG 3.93Å; Y244-H293 AromaticContact CZ-CG 3.96Å; Y244-H293 AromaticContact CZ-ND1 3.96Å; Y244-H293 VanDerWaalsContact OH-CB 3.28Å; Y244-H293 WeakPolarHBondContact OH-CB 3.46Å; Y244-H293 PolarHBondContact OH-ND1 3Å
245R87.8Confident92.6Very high170 Ų17078.5 Ų78.564%0.64237%0.366SS*.SBendtrans-127.7123.7178.8-69-177.1-171.4-167.11108.8T243 G247 K248T243-R245 PolarHBondContact O-N 3Å; T243-R245 PolarHBondContact OG1-N 3.29Å; R245-G247 PolarHBondContact O-N 3.08Å; R245-K248 HydrophobicContact CB-CB 4.01Å; R245-K248 PolarHBondContact O-N 3.21Å; R245-K248 VanDerWaalsContact O-N 3.12Å
246E84.6Confident92.6Very high202 Ų20281.1 Ų81.194%0.94438%0.381SS*.THydrogen-bonded Turntrans-54.8134176-165.9177.2-179.700110.5K248E246-K248 PolarHBondContact O-N 3.32Å
247G85.3Confident92.6Very high85 Ų8583 Ų8388%0.87640%0.397SS*.THydrogen-bonded Turntrans72.22.5-179.600000116.1R245R245-G247 PolarHBondContact O-N 3.08Å
248K91.8Very high92.8Very high119 Ų11975.3 Ų75.352%0.51737%0.368SS..  trans-113.6105.5178-171-179.4180171.90111.6T243 R245 E246T243-K248 WeakPolarHBondContact CB-O 3.37Å; T243-K248 HydrophobicContact CG2-CD 4.42Å; T243-K248 HydrophobicContact CG2-CG 4.2Å; T243-K248 WeakPolarHBondContact CG2-O 3.47Å; T243-K248 PolarHBondContact OG1-O 3.03Å; R245-K248 HydrophobicContact CB-CB 4.01Å; R245-K248 PolarHBondContact O-N 3.21Å; R245-K248 VanDerWaalsContact O-N 3.12Å; E246-K248 PolarHBondContact O-N 3.32Å
249L91.7Very high92.8Very high107 Ų10774.8 Ų74.856%0.5637%0.366SS*.  trans-72.6143.1174.8-53.8178.2000111.5E253 Y254L249-E253 WeakPolarHBondContact CA-OE2 3.44Å; L249-E253 HydrophobicContact CB-CB 4.27Å; L249-E253 WeakPolarHBondContact CD2-OE2 3.49Å; L249-Y254 HydrophobicContact CB-CD1 4.14Å
250A94.4Very high92.8Very high9 Ų978 Ų787%0.07438%0.38CS..  trans-72.9158.216700000110.7T243 W252 E253 Y254T243-A250 HydrophobicContact CG2-CB 3.91Å; A250-W252 VanDerWaalsContact C-N 3.27Å; A250-W252 VanDerWaalsContact CB-CD1 3.47Å; A250-W252 HydrophobicContact CB-CD2 4.45Å; A250-W252 HydrophobicContact CB-CG 4.23Å; A250-W252 PolarHBondContact O-N 3.46Å; A250-E253 HydrophobicContact CB-CG 4.17Å; A250-E253 VanDerWaalsContact CB-OE1 3.22Å; A250-E253 WeakPolarHBondContact CB-OE1 3.47Å; A250-E253 VanDerWaalsContact N-CD 3.33Å; A250-E253 PolarHBondContact N-OE1 3.25Å; A250-E253 WeakPolarHBondContact O-CB 3.41Å; A250-E253 PolarHBondContact O-N 3.42Å; A250-Y254 VanDerWaalsContact O-CD1 3.27Å; A250-Y254 WeakPolarHBondContact O-CD1 3.41Å; A250-Y254 WeakPolarHBondContact O-CE1 3.45Å
251R95.4Very high92.8Very high129 Ų12979 Ų7949%0.48739%0.391SS..Hα-helixtrans-57.3-41.2-178.5-175.3178167.4-177.9-1.6112.7E253 Y254 D255 Y258R251-E253 PolarHBondContact O-N 3.27Å; R251-Y254 HydrophobicContact CB-CE1 4.5Å; R251-Y254 HydrophobicContact CG-CE2 4.31Å; R251-Y254 PolarHBondContact O-N 2.82Å; R251-D255 HydrophobicContact CG-CB 4.08Å; R251-D255 IonicContact CZ-OD2 2.8Å; R251-D255 IonicContact NE-OD2 3.81Å; R251-D255 PolarHBondContact NE-OD2 3.12Å; R251-D255 IonicContact NH2-OD2 3.95Å; R251-D255 PolarHBondContact NH2-OD2 2.57Å; R251-D255 VanDerWaalsContact O-CB 3.24Å; R251-D255 WeakPolarHBondContact O-CB 3.46Å; R251-D255 PolarHBondContact O-N 2.8Å; R251-Y258 HydrophobicContact CB-CD2 4.16Å; R251-Y258 HydrophobicContact CB-CE2 4Å; R251-Y258 HydrophobicContact CG-CD2 3.77Å; R251-Y258 HydrophobicContact CG-CE2 3.99Å
252W96.5Very high92.8Very high10 Ų1078.6 Ų78.64%0.03839%0.386CS..Hα-helixtrans-65.5-16.6179.964.2-99.4000113.9W240 G241 R242 A250 Y258 A328 Q332W240-W252 VanDerWaalsContact C-NE1 3.31Å; W240-W252 HydrophobicContact CB-CD2 4.42Å; W240-W252 HydrophobicContact CB-CG 4.35Å; W240-W252 AromaticContact CD1-CD2 3.8Å; W240-W252 AromaticContact CD1-CG 3.6Å; W240-W252 HydrophobicContact CG-CB 4.4Å; W240-W252 HydrophobicContact CG-CG 4.24Å; W240-W252 PolarHBondContact O-NE1 3.33Å; G241-W252 PolarHBondContact O-NE1 3.16Å; G241-W252 VanDerWaalsContact O-NE1 3.12Å; R242-W252 HydrophobicContact CG-CZ2 4.09Å; A250-W252 VanDerWaalsContact C-N 3.27Å; A250-W252 VanDerWaalsContact CB-CD1 3.47Å; A250-W252 HydrophobicContact CB-CD2 4.45Å; A250-W252 HydrophobicContact CB-CG 4.23Å; A250-W252 PolarHBondContact O-N 3.46Å; W252-Y258 HydrophobicContact CB-CD1 3.36Å; W252-Y258 HydrophobicContact CB-CD2 4.2Å; W252-Y258 HydrophobicContact CB-CE1 3.58Å; W252-Y258 HydrophobicContact CB-CE2 4.39Å; W252-Y258 HydrophobicContact CB-CG 3.69Å; W252-A328 HydrophobicContact CE3-CB 3.77Å; W252-A328 HydrophobicContact CZ3-CB 3.88Å; W252-Q332 PolarHBondContact O-NE2 3.12Å
253E94.9Very high92.9Very high71 Ų7179.5 Ų79.533%0.33239%0.391SS..Hα-helixtrans-79.4-23.4-179.3-65.5170.3-139.800112.7L249 A250 R251L249-E253 WeakPolarHBondContact CA-OE2 3.44Å; L249-E253 HydrophobicContact CB-CB 4.27Å; L249-E253 WeakPolarHBondContact CD2-OE2 3.49Å; A250-E253 HydrophobicContact CB-CG 4.17Å; A250-E253 VanDerWaalsContact CB-OE1 3.22Å; A250-E253 WeakPolarHBondContact CB-OE1 3.47Å; A250-E253 VanDerWaalsContact N-CD 3.33Å; A250-E253 PolarHBondContact N-OE1 3.25Å; A250-E253 WeakPolarHBondContact O-CB 3.41Å; A250-E253 PolarHBondContact O-N 3.42Å; R251-E253 PolarHBondContact O-N 3.27Å
254Y94.3Very high93.1Very high152 Ų15285.1 Ų85.160%0.59641%0.412SS*.Hα-helixtrans-123.2-17.3-178.663.3-101000114.6L249 A250 R251L249-Y254 HydrophobicContact CB-CD1 4.14Å; A250-Y254 VanDerWaalsContact O-CD1 3.27Å; A250-Y254 WeakPolarHBondContact O-CD1 3.41Å; A250-Y254 WeakPolarHBondContact O-CE1 3.45Å; R251-Y254 HydrophobicContact CB-CE1 4.5Å; R251-Y254 HydrophobicContact CG-CE2 4.31Å; R251-Y254 PolarHBondContact O-N 2.82Å
255D95.1Very high93.3Very high25 Ų2586.5 Ų86.513%0.13442%0.423CS..  trans-93.6101.1178-176.7-4.9000109.7R251 S257 Y258R251-D255 HydrophobicContact CG-CB 4.08Å; R251-D255 IonicContact CZ-OD2 2.8Å; R251-D255 IonicContact NE-OD2 3.81Å; R251-D255 PolarHBondContact NE-OD2 3.12Å; R251-D255 IonicContact NH2-OD2 3.95Å; R251-D255 PolarHBondContact NH2-OD2 2.57Å; R251-D255 VanDerWaalsContact O-CB 3.24Å; R251-D255 WeakPolarHBondContact O-CB 3.46Å; R251-D255 PolarHBondContact O-N 2.8Å; D255-S257 PolarHBondContact O-N 3.05Å; D255-S257 WeakPolarHBondContact OD1-CA 3.45Å; D255-S257 PolarHBondContact OD1-N 2.91Å; D255-S257 PolarHBondContact OD1-OG 3.47Å; D255-Y258 WeakPolarHBondContact O-CB 3.43Å; D255-Y258 PolarHBondContact O-N 3.46Å; D255-Y258 VanDerWaalsContact O-N 3.1Å; D255-Y258 PolarHBondContact OD1-N 3.46Å
256E90.6Very high93.4Very high185 Ų18582.7 Ų82.786%0.86442%0.42SS*.THydrogen-bonded Turntrans-62.5-24.6178.1-65.1-175169.400112.6Y258E256-Y258 VanDerWaalsContact C-N 3.33Å
257S94.1Very high93.6Very high70 Ų7075.9 Ų75.949%0.4939%0.393SS..THydrogen-bonded Turntrans-91.79.2178.271.50000113.5D255 C259 E260D255-S257 PolarHBondContact O-N 3.05Å; D255-S257 WeakPolarHBondContact OD1-CA 3.45Å; D255-S257 PolarHBondContact OD1-N 2.91Å; D255-S257 PolarHBondContact OD1-OG 3.47Å; S257-C259 VanDerWaalsContact C-N 3.29Å; S257-C259 PolarHBondContact O-N 2.96Å; S257-E260 WeakPolarHBondContact O-CB 3.44Å; S257-E260 PolarHBondContact O-N 2.68Å
258Y97.3Very high93.9Very high30 Ų3072.7 Ų72.712%0.11836%0.355CS..Hα-helixtrans-54.8-41.2-172.9-178.2-103.4000113.3P239 W240 R251 W252 D255 E256 E260 A261 V262P239-Y258 HydrophobicContact CB-CE1 4.35Å; P239-Y258 PolarHBondContact O-OH 2.84Å; W240-Y258 HydrophobicContact CD2-CE1 4.17Å; W240-Y258 AromaticContact CE2-CD1 3.81Å; W240-Y258 AromaticContact CE2-CE1 3.84Å; W240-Y258 HydrophobicContact CG-CE1 4.45Å; W240-Y258 HydrophobicContact CZ2-CD1 4.02Å; W240-Y258 HydrophobicContact CZ2-CE1 4.18Å; W240-Y258 AromaticContact NE1-CD1 3.65Å; W240-Y258 AromaticContact NE1-CE1 3.93Å; R251-Y258 HydrophobicContact CB-CD2 4.16Å; R251-Y258 HydrophobicContact CB-CE2 4Å; R251-Y258 HydrophobicContact CG-CD2 3.77Å; R251-Y258 HydrophobicContact CG-CE2 3.99Å; W252-Y258 HydrophobicContact CB-CD1 3.36Å; W252-Y258 HydrophobicContact CB-CD2 4.2Å; W252-Y258 HydrophobicContact CB-CE1 3.58Å; W252-Y258 HydrophobicContact CB-CE2 4.39Å; W252-Y258 HydrophobicContact CB-CG 3.69Å; D255-Y258 WeakPolarHBondContact O-CB 3.43Å; D255-Y258 PolarHBondContact O-N 3.46Å; D255-Y258 VanDerWaalsContact O-N 3.1Å; D255-Y258 PolarHBondContact OD1-N 3.46Å; E256-Y258 VanDerWaalsContact C-N 3.33Å; Y258-E260 VanDerWaalsContact C-N 3.27Å; Y258-E260 PolarHBondContact O-N 3.21Å; Y258-A261 WeakPolarHBondContact O-CB 3.47Å; Y258-A261 PolarHBondContact O-N 3.29Å; Y258-A261 VanDerWaalsContact O-N 3.09Å; Y258-V262 HydrophobicContact CD1-CG2 3.84Å; Y258-V262 HydrophobicContact CE1-CG2 3.37Å; Y258-V262 HydrophobicContact CE2-CG2 4.45Å; Y258-V262 PolarHBondContact O-N 3.2Å; Y258-V262 VanDerWaalsContact O-N 3.11Å
259C96.9Very high93.8Very high1 Ų171.2 Ų71.21%0.00735%0.352CS..Hα-helixtrans-62.8-33179.7-174.30000112.9W240 S257 A261 V262 K263 Q332 C333W240-C259 HydrophobicContact CZ2-CB 4.11Å; S257-C259 VanDerWaalsContact C-N 3.29Å; S257-C259 PolarHBondContact O-N 2.96Å; C259-A261 PolarHBondContact O-N 2.03Å; C259-V262 PolarHBondContact O-N 3.18Å; C259-K263 WeakPolarHBondContact O-CG 3.49Å; C259-K263 PolarHBondContact O-N 3.46Å; C259-Q332 HydrophobicContact CB-CB 3.94Å; C259-C333 HydrophobicContact CB-CB 4.04Å; C259-C333 WeakPolarHBondContact CB-SG 3.2Å; C259-C333 WeakPolarHBondContact SG-CA 3.14Å; C259-C333 WeakPolarHBondContact SG-CB 3.42Å; C259-C333 CovalentContact SG-SG 2.02Å; C259-C333 PolarHBondContact SG-SG 3.12Å
260E95.8Very high93.5Very high89 Ų8969.4 Ų69.442%0.41635%0.353SS..Hα-helixtrans-66.6-26.8177.2-63.8-55.2125.300112.6S257 Y258 K263 K264S257-E260 WeakPolarHBondContact O-CB 3.44Å; S257-E260 PolarHBondContact O-N 2.68Å; Y258-E260 VanDerWaalsContact C-N 3.27Å; Y258-E260 PolarHBondContact O-N 3.21Å; E260-K263 IonicContact OE1-NZ 2.92Å; E260-K263 PolarHBondContact OE1-NZ 3.04Å; E260-K264 WeakPolarHBondContact O-CG 3.49Å
261A96Very high93Very high36 Ų3672 Ų7230%0.29838%0.381SS..Hα-helixtrans-75.3-39.5169.500000111.6Y258 C259 K264Y258-A261 WeakPolarHBondContact O-CB 3.47Å; Y258-A261 PolarHBondContact O-N 3.29Å; Y258-A261 VanDerWaalsContact O-N 3.09Å; C259-A261 PolarHBondContact O-N 2.03Å; A261-K264 PolarHBondContact O-N 3.04Å
262V96.5Very high92.7Very high2 Ų266.4 Ų66.41%0.01236%0.361CS..Hα-helixtrans-64.2-43177.5177.50000111.3P239 W240 Y258 C259 K264 M265 Y268 L274P239-V262 HydrophobicContact CB-CG1 4.26Å; P239-V262 HydrophobicContact CB-CG2 4.05Å; P239-V262 HydrophobicContact CG-CG1 4.27Å; W240-V262 HydrophobicContact CH2-CB 4.07Å; W240-V262 HydrophobicContact CH2-CG1 3.82Å; W240-V262 HydrophobicContact CH2-CG2 4.01Å; W240-V262 HydrophobicContact CZ2-CG2 4.29Å; W240-V262 HydrophobicContact CZ3-CG1 4Å; W240-V262 HydrophobicContact CZ3-CG2 4.46Å; Y258-V262 HydrophobicContact CD1-CG2 3.84Å; Y258-V262 HydrophobicContact CE1-CG2 3.37Å; Y258-V262 HydrophobicContact CE2-CG2 4.45Å; Y258-V262 PolarHBondContact O-N 3.2Å; Y258-V262 VanDerWaalsContact O-N 3.11Å; C259-V262 PolarHBondContact O-N 3.18Å; V262-K264 PolarHBondContact O-N 3.23Å; V262-M265 WeakPolarHBondContact O-CB 3.24Å; V262-M265 PolarHBondContact O-N 2.97Å; V262-Y268 HydrophobicContact CG1-CD2 3.89Å; V262-Y268 HydrophobicContact CG1-CG 3.88Å; V262-L274 HydrophobicContact CG1-CD1 4.27Å
263K94.9Very high92.5Very high62 Ų6266.3 Ų66.327%0.2736%0.361SS..THydrogen-bonded Turntrans-57.9-12.8176.2-74.9174.5-179.1170.80114.3C259 E260 D269 L274C259-K263 WeakPolarHBondContact O-CG 3.49Å; C259-K263 PolarHBondContact O-N 3.46Å; E260-K263 IonicContact OE1-NZ 2.92Å; E260-K263 PolarHBondContact OE1-NZ 3.04Å; K263-D269 VanDerWaalsContact O-CA 3.27Å; K263-D269 WeakPolarHBondContact O-CA 3.38Å; K263-L274 HydrophobicContact CG-CD2 3.65Å
264K94.4Very high92.4Very high161 Ų16163.4 Ų63.470%0.735%0.347SS*.THydrogen-bonded Turntrans-107.21.8178.9-62.1174.3-172.2175.40112.9E260 A261 V262E260-K264 WeakPolarHBondContact O-CG 3.49Å; A261-K264 PolarHBondContact O-N 3.04Å; V262-K264 PolarHBondContact O-N 3.23Å
265M92.1Very high92.4Very high102 Ų10256.6 Ų56.650%0.50232%0.321SS..SBendtrans-108.3126.3-174.5-176.1-176.4-62.300110.3V262 Y268 D269V262-M265 WeakPolarHBondContact O-CB 3.24Å; V262-M265 PolarHBondContact O-N 2.97Å; M265-Y268 WeakPolarHBondContact O-CA 3.49Å; M265-Y268 WeakPolarHBondContact O-CB 3.25Å; M265-Y268 WeakPolarHBondContact O-CD2 3.43Å; M265-Y268 PolarHBondContact O-N 3.02Å; M265-D269 PolarHBondContact O-N 3.41Å
266P88.9Confident92.4Very high90 Ų9055.4 Ų55.458%0.58432%0.315SS*.THydrogen-bonded Turntrans-59.6140.2169.7-2432.9000112.3D269P266-D269 VanDerWaalsContact CA-OD1 3.29Å; P266-D269 WeakPolarHBondContact CA-OD1 3.37Å
267P89.7Confident92.7Very high58 Ų5846.6 Ų46.638%0.37727%0.274SS..THydrogen-bonded Turncis-93.722.80.637.7-36.4000114.3R273P267-R273 HydrophobicContact CG-CG 4.17Å; P267-R273 WeakPolarHBondContact O-CB 3.45Å
268Y91.6Very high92.8Very high18 Ų1843.3 Ų43.37%0.07125%0.251CS..SBendtrans-93.6-8.7-176-48.2-72.3000113.7R237 P239 V262 M265 A270 R273 V277 Y295R237-Y268 PolarHBondContact O-OH 2.66Å; P239-Y268 WeakPolarHBondContact CD-OH 3.41Å; P239-Y268 HydrophobicContact CG-CD2 4.26Å; P239-Y268 HydrophobicContact CG-CE1 3.92Å; P239-Y268 HydrophobicContact CG-CE2 3.52Å; P239-Y268 WeakPolarHBondContact CG-OH 3.43Å; V262-Y268 HydrophobicContact CG1-CD2 3.89Å; V262-Y268 HydrophobicContact CG1-CG 3.88Å; M265-Y268 WeakPolarHBondContact O-CA 3.49Å; M265-Y268 WeakPolarHBondContact O-CB 3.25Å; M265-Y268 WeakPolarHBondContact O-CD2 3.43Å; M265-Y268 PolarHBondContact O-N 3.02Å; Y268-A270 VanDerWaalsContact C-N 3.32Å; Y268-R273 HydrophobicContact CD1-CB 4.47Å; Y268-R273 HydrophobicContact CD1-CG 3.83Å; Y268-R273 HydrophobicContact CE1-CG 3.83Å; Y268-V277 HydrophobicContact CE1-CG2 3.99Å; Y268-Y295 HydrophobicContact CE1-CE1 4.45Å; Y268-Y295 WeakPolarHBondContact CE1-OH 3.4Å; Y268-Y295 WeakPolarHBondContact OH-CE1 3.35Å; Y268-Y295 PolarHBondContact OH-OH 3.42Å
269D89.1Confident92.7Very high88 Ų8842 Ų4247%0.47125%0.245SC..SBendtrans-77.8-16178.861.4-24000113.7K263 M265 P266K263-D269 VanDerWaalsContact O-CA 3.27Å; K263-D269 WeakPolarHBondContact O-CA 3.38Å; M265-D269 PolarHBondContact O-N 3.41Å; P266-D269 VanDerWaalsContact CA-OD1 3.29Å; P266-D269 WeakPolarHBondContact CA-OD1 3.37Å
270A84.3Confident92.7Very high69 Ų6941.9 Ų41.957%0.5725%0.245SC*.SBendtrans-147.1163.4175.800000112.2Y268Y268-A270 VanDerWaalsContact C-N 3.32Å
271G85.5Confident92.8Very high64 Ų6437.8 Ų37.866%0.6623%0.226SC*.THydrogen-bonded Turntrans71-165.5174.200000114.6R273G271-R273 VanDerWaalsContact C-N 3.32Å; G271-R273 PolarHBondContact O-N 3.25Å
272P89.2Confident92.8Very high11 Ų1136 Ų367%0.07121%0.212CC..THydrogen-bonded Turntrans-83.8-4.7-170.933.1-36.2000113.8L274 L275 D276 M406P272-L274 PolarHBondContact O-N 3.48Å; P272-L275 PolarHBondContact O-N 2.91Å; P272-L275 VanDerWaalsContact O-N 3.16Å; P272-D276 PolarHBondContact O-N 2.72Å; P272-M406 HydrophobicContact CB-SD 4.08Å; P272-M406 HydrophobicContact CG-SD 4.07Å
273R91.1Very high92.9Very high9 Ų936 Ų363%0.03421%0.211CC..Hα-helixtrans-62.6-41.8-164.6-173.159.660.5126.9-2.3113.5P267 Y268 G271 D276 V277 Y295 S297 S305P267-R273 HydrophobicContact CG-CG 4.17Å; P267-R273 WeakPolarHBondContact O-CB 3.45Å; Y268-R273 HydrophobicContact CD1-CB 4.47Å; Y268-R273 HydrophobicContact CD1-CG 3.83Å; Y268-R273 HydrophobicContact CE1-CG 3.83Å; G271-R273 VanDerWaalsContact C-N 3.32Å; G271-R273 PolarHBondContact O-N 3.25Å; R273-D276 PolarHBondContact O-N 2.99Å; R273-V277 WeakPolarHBondContact O-CG2 3.41Å; R273-V277 PolarHBondContact O-N 2.82Å; R273-Y295 VanDerWaalsContact NH1-CE2 3.26Å; R273-S297 PolarHBondContact NH1-OG 3.16Å; R273-S297 PolarHBondContact NH2-OG 3.43Å; R273-S305 PolarHBondContact NH2-O 3.09Å; R273-S305 PolarHBondContact NH2-OG 2.74Å
274L94.1Very high93Very high9 Ų933.2 Ų33.25%0.04720%0.2CC..Hα-helixtrans-65.8-41.2177.9-178.458.8000111.6W240 V262 K263 P272 D276 V277 I278 M335W240-L274 HydrophobicContact CH2-CD1 4.04Å; W240-L274 HydrophobicContact CZ3-CD1 4.2Å; V262-L274 HydrophobicContact CG1-CD1 4.27Å; K263-L274 HydrophobicContact CG-CD2 3.65Å; P272-L274 PolarHBondContact O-N 3.48Å; L274-D276 VanDerWaalsContact C-N 3.3Å; L274-D276 PolarHBondContact O-N 3.41Å; L274-V277 WeakPolarHBondContact O-CB 3.16Å; L274-V277 PolarHBondContact O-N 3.02Å; L274-I278 HydrophobicContact CG-CD1 4.28Å; L274-I278 WeakPolarHBondContact O-CG1 3.24Å; L274-I278 PolarHBondContact O-N 3.46Å; L274-M335 HydrophobicContact CD2-CE 4.22Å; L274-M335 HydrophobicContact CD2-SD 3.71Å; L274-M335 HydrophobicContact CG-SD 4.24Å
275L94.2Very high93.2Very high10 Ų1026.4 Ų26.45%0.05217%0.17CC..Hα-helixtrans-64.8-35.9174.5-70.1174.6000111.8P272 I278 D279 M335 I402 D404P272-L275 PolarHBondContact O-N 2.91Å; P272-L275 VanDerWaalsContact O-N 3.16Å; L275-I278 PolarHBondContact O-N 2.99Å; L275-D279 PolarHBondContact O-N 3.18Å; L275-M335 HydrophobicContact CD2-CE 3.55Å; L275-M335 HydrophobicContact CD2-CG 4.32Å; L275-M335 HydrophobicContact CG-CE 4.01Å; L275-I402 HydrophobicContact CD1-CB 4.26Å; L275-I402 HydrophobicContact CD1-CG2 3.95Å; L275-I402 HydrophobicContact CD2-CB 4.24Å; L275-I402 HydrophobicContact CD2-CG1 4.28Å; L275-D404 HydrophobicContact CD1-CB 4.37Å
276D94.1Very high93.4Very high0 Ų021.6 Ų21.60%015%0.146CC..Hα-helixtrans-65.1-40.2174.8-69.8-22.4000111.9R74 R163 P272 R273 L274 I278 D279 T280 L307 R337R74-D276 IonicContact CZ-OD1 2.97Å; R74-D276 IonicContact CZ-OD2 3.8Å; R74-D276 VanDerWaalsContact CZ-OD2 3.29Å; R74-D276 IonicContact NH1-OD2 3.39Å; R74-D276 PolarHBondContact NH1-OD2 2.81Å; R74-D276 VanDerWaalsContact NH2-CG 3.3Å; R74-D276 IonicContact NH2-OD1 2.72Å; R74-D276 PolarHBondContact NH2-OD1 3.28Å; R74-D276 IonicContact NH2-OD2 2.83Å; R74-D276 PolarHBondContact NH2-OD2 2.89Å; R163-D276 IonicContact CZ-OD1 3.12Å; R163-D276 PolarHBondContact NH1-O 2.97Å; R163-D276 IonicContact NH1-OD1 3.47Å; R163-D276 IonicContact NH2-OD1 3.4Å; R163-D276 PolarHBondContact NH2-OD1 3.32Å; P272-D276 PolarHBondContact O-N 2.72Å; R273-D276 PolarHBondContact O-N 2.99Å; L274-D276 VanDerWaalsContact C-N 3.3Å; L274-D276 PolarHBondContact O-N 3.41Å; D276-I278 VanDerWaalsContact C-N 3.3Å; D276-I278 PolarHBondContact O-N 3.42Å; D276-D279 PolarHBondContact O-N 3.36Å; D276-T280 WeakPolarHBondContact O-CB 3.41Å; D276-T280 PolarHBondContact O-N 3.45Å; D276-T280 PolarHBondContact O-OG1 3.35Å; D276-T280 VanDerWaalsContact O-OG1 3.05Å; D276-L307 HydrophobicContact CB-CB 4.15Å; D276-R337 IonicContact OD1-CZ 3.06Å; D276-R337 IonicContact OD1-NH1 2.84Å; D276-R337 IonicContact OD1-NH2 2.79Å; D276-R337 PolarHBondContact OD1-NH2 3.47Å; D276-R337 VanDerWaalsContact OD1-NH2 3.12Å
277V95.9Very high93.8Very high0 Ų017.3 Ų17.30%012%0.118CC..Hα-helixtrans-60.5-40.8172.4170.10000111.2W240 Y268 R273 L274 T280 A281 Y295 L307 P329W240-V277 HydrophobicContact CE3-CG1 4.02Å; W240-V277 HydrophobicContact CZ3-CG1 3.97Å; Y268-V277 HydrophobicContact CE1-CG2 3.99Å; R273-V277 WeakPolarHBondContact O-CG2 3.41Å; R273-V277 PolarHBondContact O-N 2.82Å; L274-V277 WeakPolarHBondContact O-CB 3.16Å; L274-V277 PolarHBondContact O-N 3.02Å; V277-T280 PolarHBondContact O-N 3.29Å; V277-A281 WeakPolarHBondContact O-CB 3.44Å; V277-A281 PolarHBondContact O-N 3.13Å; V277-Y295 HydrophobicContact CG2-CE1 4.31Å; V277-L307 HydrophobicContact CG2-CD1 4.13Å; V277-P329 HydrophobicContact CG1-CB 4.31Å; V277-P329 HydrophobicContact CG1-CG 4.36Å
278I96.9Very high94.2Very high1 Ų115.4 Ų15.41%0.00511%0.109CC..Hα-helixtrans-70.3-42.7-179.7-65.3165.2000111.7L274 L275 D276 T280 A281 V282 P329 L330 C333 M335L274-I278 HydrophobicContact CG-CD1 4.28Å; L274-I278 WeakPolarHBondContact O-CG1 3.24Å; L274-I278 PolarHBondContact O-N 3.46Å; L275-I278 PolarHBondContact O-N 2.99Å; D276-I278 VanDerWaalsContact C-N 3.3Å; D276-I278 PolarHBondContact O-N 3.42Å; I278-T280 VanDerWaalsContact C-N 3.27Å; I278-T280 PolarHBondContact O-N 2.87Å; I278-A281 WeakPolarHBondContact O-CB 3.46Å; I278-A281 PolarHBondContact O-N 3.08Å; I278-V282 PolarHBondContact O-N 3.47Å; I278-P329 HydrophobicContact CG1-CB 3.98Å; I278-L330 HydrophobicContact CG2-CB 4.19Å; I278-L330 HydrophobicContact CG2-CD1 3.8Å; I278-C333 HydrophobicContact CD1-CB 3.91Å; I278-M335 HydrophobicContact CD1-CG 3.27Å; I278-M335 WeakPolarHBondContact CD1-O 3.47Å; I278-M335 HydrophobicContact CD1-SD 4.05Å; I278-M335 WeakPolarHBondContact CG2-O 3.38Å
279D95.4Very high94.5Very high1 Ų114.8 Ų14.81%0.00511%0.107CC..Hα-helixtrans-56.6-45171.5-79.9-13.7000111.3F161 R163 L275 D276 A281 V282 F283 R337 T340F161-D279 HydrophobicContact CD1-CB 4.31Å; F161-D279 HydrophobicContact CE1-CB 3.63Å; F161-D279 VanDerWaalsContact CE1-CG 3.48Å; F161-D279 HydrophobicContact CZ-CB 3.9Å; R163-D279 IonicContact CZ-OD2 2.65Å; R163-D279 IonicContact NH1-OD2 2.86Å; R163-D279 IonicContact NH2-OD2 3.82Å; R163-D279 PolarHBondContact NH2-OD2 3.48Å; L275-D279 PolarHBondContact O-N 3.18Å; D276-D279 PolarHBondContact O-N 3.36Å; D279-A281 VanDerWaalsContact C-N 3.32Å; D279-A281 PolarHBondContact O-N 3.19Å; D279-V282 WeakPolarHBondContact O-CB 3.45Å; D279-V282 PolarHBondContact O-N 3.35Å; D279-F283 PolarHBondContact O-N 2.62Å; D279-R337 IonicContact OD1-NH1 3.52Å; D279-R337 IonicContact OD2-CZ 2.88Å; D279-R337 IonicContact OD2-NH1 3.45Å; D279-R337 PolarHBondContact OD2-NH1 3.21Å; D279-T340 WeakPolarHBondContact OD1-CB 3.46Å; D279-T340 WeakPolarHBondContact OD1-CG2 3.29Å; D279-T340 PolarHBondContact OD1-OG1 2.91Å
280T96.3Very high94.8Very high0 Ų011 Ų110%09%0.088CC..Hα-helixtrans-64.6-37177.7-67.10000111.6D276 V277 I278 F283 D284 L307 L309D276-T280 WeakPolarHBondContact O-CB 3.41Å; D276-T280 PolarHBondContact O-N 3.45Å; D276-T280 PolarHBondContact O-OG1 3.35Å; D276-T280 VanDerWaalsContact O-OG1 3.05Å; V277-T280 PolarHBondContact O-N 3.29Å; I278-T280 VanDerWaalsContact C-N 3.27Å; I278-T280 PolarHBondContact O-N 2.87Å; T280-F283 WeakPolarHBondContact O-CB 3.02Å; T280-F283 PolarHBondContact O-N 3.18Å; T280-D284 VanDerWaalsContact O-CB 3.32Å; T280-D284 WeakPolarHBondContact O-CB 3.28Å; T280-D284 PolarHBondContact O-N 2.74Å; T280-L307 HydrophobicContact CG2-CD1 4.36Å; T280-L307 HydrophobicContact CG2-CD2 3.99Å; T280-L307 WeakPolarHBondContact OG1-CD2 3.43Å; T280-L309 HydrophobicContact CG2-CD2 3.61Å
281A97.6Very high95.4Very high2 Ų29.1 Ų9.12%0.0177%0.068CC..Hα-helixtrans-65.4-38.5174.300000112.3V277 I278 D279 Y285 P329V277-A281 WeakPolarHBondContact O-CB 3.44Å; V277-A281 PolarHBondContact O-N 3.13Å; I278-A281 WeakPolarHBondContact O-CB 3.46Å; I278-A281 PolarHBondContact O-N 3.08Å; D279-A281 VanDerWaalsContact C-N 3.32Å; D279-A281 PolarHBondContact O-N 3.19Å; A281-Y285 VanDerWaalsContact O-CB 3.28Å; A281-Y285 WeakPolarHBondContact O-CB 3.06Å; A281-Y285 PolarHBondContact O-N 2.92Å; A281-P329 HydrophobicContact CB-CB 4.01Å; A281-P329 HydrophobicContact CB-CG 3.71Å
282V97.4Very high95.8Very high0 Ų07.2 Ų7.20%04%0.041CC..Hα-helixtrans-61.7-48.1171.5168.10000110.4I278 D279 Y285 L286 L327 L330 I336 L344 V384I278-V282 PolarHBondContact O-N 3.47Å; D279-V282 WeakPolarHBondContact O-CB 3.45Å; D279-V282 PolarHBondContact O-N 3.35Å; V282-Y285 PolarHBondContact O-N 3.15Å; V282-L286 HydrophobicContact CG1-CD1 4.3Å; V282-L286 WeakPolarHBondContact O-CG 3.5Å; V282-L286 PolarHBondContact O-N 3.48Å; V282-L286 VanDerWaalsContact O-N 3.08Å; V282-L327 HydrophobicContact CG2-CD2 4.45Å; V282-L330 HydrophobicContact CG2-CD2 4.15Å; V282-I336 HydrophobicContact CG2-CD1 4.4Å; V282-L344 HydrophobicContact CG1-CD1 4.05Å; V282-L344 HydrophobicContact CG1-CD2 4.04Å; V282-V384 HydrophobicContact CG1-CG1 3.96Å; V282-V384 HydrophobicContact CG1-CG2 4.3Å; V282-V384 HydrophobicContact CG2-CG1 3.96Å
283F97.3Very high96.1Very high0 Ų010 Ų100%05%0.053CC..Hα-helixtrans-58.4-51.5176.9176.4-97.3000111.9A150 L153 D154 F161 D279 T280 Y285 L286 I287 L309A150-F283 HydrophobicContact CB-CE1 4.46Å; A150-F283 HydrophobicContact CB-CZ 3.88Å; A150-F283 WeakPolarHBondContact O-CZ 3.29Å; L153-F283 HydrophobicContact CB-CE2 4.16Å; L153-F283 HydrophobicContact CD2-CD2 4.14Å; L153-F283 HydrophobicContact CD2-CE2 3.91Å; L153-F283 HydrophobicContact CG-CD2 4.43Å; L153-F283 HydrophobicContact CG-CE2 4.06Å; D154-F283 HydrophobicContact CB-CE2 4.09Å; D154-F283 HydrophobicContact CB-CZ 4.47Å; F161-F283 HydrophobicContact CD2-CB 4.43Å; F161-F283 HydrophobicContact CD2-CD2 4.26Å; F161-F283 HydrophobicContact CE2-CB 4.01Å; F161-F283 HydrophobicContact CE2-CD2 4.41Å; D279-F283 PolarHBondContact O-N 2.62Å; T280-F283 WeakPolarHBondContact O-CB 3.02Å; T280-F283 PolarHBondContact O-N 3.18Å; F283-Y285 VanDerWaalsContact C-N 3.28Å; F283-Y285 PolarHBondContact O-N 3.13Å; F283-L286 WeakPolarHBondContact O-CB 3.47Å; F283-L286 PolarHBondContact O-N 3.15Å; F283-I287 HydrophobicContact CD1-CD1 3.97Å; F283-I287 HydrophobicContact CE1-CD1 3.52Å; F283-I287 HydrophobicContact CZ-CD1 4.13Å; F283-I287 HydrophobicContact CZ-CG2 4.43Å; F283-I287 PolarHBondContact O-N 2.98Å; F283-I287 VanDerWaalsContact O-N 3.13Å; F283-L309 HydrophobicContact CD1-CD1 3.9Å; F283-L309 HydrophobicContact CD1-CD2 3.96Å; F283-L309 HydrophobicContact CD1-CG 4.5Å; F283-L309 HydrophobicContact CD2-CD1 4.17Å; F283-L309 HydrophobicContact CE1-CD1 3.9Å; F283-L309 HydrophobicContact CE1-CD2 4.29Å; F283-L309 HydrophobicContact CE1-CG 4.48Å; F283-L309 HydrophobicContact CE2-CD1 4.18Å; F283-L309 HydrophobicContact CG-CD1 4.02Å; F283-L309 HydrophobicContact CZ-CD1 4.03Å
284D97.9Very high96.2Very high5 Ų512.8 Ų12.83%0.0277%0.066CC..Hα-helixtrans-60.2-38.2179.1-79-27.2000111.7T280 I287 G288 N289 R292 I326T280-D284 VanDerWaalsContact O-CB 3.32Å; T280-D284 WeakPolarHBondContact O-CB 3.28Å; T280-D284 PolarHBondContact O-N 2.74Å; D284-I287 WeakPolarHBondContact O-CG1 3.37Å; D284-I287 PolarHBondContact O-N 3.15Å; D284-G288 CarbonylContact O-C 3.58Å; D284-G288 VanDerWaalsContact O-CA 3.31Å; D284-G288 WeakPolarHBondContact O-CA 3.18Å; D284-G288 PolarHBondContact O-N 3.26Å; D284-N289 HydrophobicContact CB-CB 4.08Å; D284-N289 PolarHBondContact O-N 3.07Å; D284-N289 WeakPolarHBondContact OD1-CB 3.29Å; D284-N289 PolarHBondContact OD1-ND2 3.49Å; D284-R292 VanDerWaalsContact CG-NE 3.33Å; D284-R292 IonicContact OD1-CZ 3.59Å; D284-R292 IonicContact OD1-NE 2.92Å; D284-R292 PolarHBondContact OD1-NE 2.96Å; D284-R292 IonicContact OD1-NH2 2.74Å; D284-R292 PolarHBondContact OD1-NH2 3.26Å; D284-R292 VanDerWaalsContact OD2-CD 3.26Å; D284-R292 WeakPolarHBondContact OD2-CD 3.47Å; D284-R292 IonicContact OD2-CZ 3.66Å; D284-R292 IonicContact OD2-NE 2.75Å; D284-R292 PolarHBondContact OD2-NE 3.25Å; D284-R292 IonicContact OD2-NH2 2.7Å; D284-I326 HydrophobicContact CB-CG2 3.61Å
285Y98.3Very high96.2Very high18 Ų1812.6 Ų12.67%0.0717%0.065CC..Hα-helixtrans-66.5-42.6177.3176.6-105.9000111.9A281 V282 F283 I287 G288 D322 E323 I326 L327 R380 V384A281-Y285 VanDerWaalsContact O-CB 3.28Å; A281-Y285 WeakPolarHBondContact O-CB 3.06Å; A281-Y285 PolarHBondContact O-N 2.92Å; V282-Y285 PolarHBondContact O-N 3.15Å; F283-Y285 VanDerWaalsContact C-N 3.28Å; F283-Y285 PolarHBondContact O-N 3.13Å; Y285-I287 VanDerWaalsContact C-N 3.34Å; Y285-I287 PolarHBondContact O-N 3.07Å; Y285-G288 PolarHBondContact O-N 3.44Å; Y285-D322 HydrophobicContact CE2-CB 4.38Å; Y285-E323 WeakPolarHBondContact CD2-O 3.28Å; Y285-I326 HydrophobicContact CD2-CB 4.28Å; Y285-L327 HydrophobicContact CD1-CD1 3.65Å; Y285-L327 HydrophobicContact CD1-CD2 3.94Å; Y285-L327 HydrophobicContact CD1-CG 3.83Å; Y285-L327 HydrophobicContact CD2-CD1 4.02Å; Y285-L327 HydrophobicContact CD2-CD2 4.41Å; Y285-L327 HydrophobicContact CD2-CG 3.7Å; Y285-L327 HydrophobicContact CE1-CD1 3.65Å; Y285-L327 HydrophobicContact CE1-CG 4.28Å; Y285-L327 HydrophobicContact CE2-CD1 4.05Å; Y285-L327 HydrophobicContact CE2-CG 4.2Å; Y285-L327 HydrophobicContact CG-CD1 3.81Å; Y285-L327 HydrophobicContact CG-CD2 3.71Å; Y285-L327 HydrophobicContact CG-CG 3.47Å; Y285-L327 VanDerWaalsContact CG-CG 3.47Å; Y285-R380 HydrophobicContact CD1-CB 4.19Å; Y285-R380 HydrophobicContact CE1-CB 3.78Å; Y285-R380 HydrophobicContact CE1-CG 4.2Å; Y285-R380 WeakPolarHBondContact CE1-O 3.17Å; Y285-R380 WeakPolarHBondContact O-CD 3.27Å; Y285-V384 HydrophobicContact CD1-CG2 3.49Å; Y285-V384 VanDerWaalsContact CD1-CG2 3.49Å; Y285-V384 HydrophobicContact CE1-CG2 3.87Å
286L97.6Very high96.2Very high1 Ų114.5 Ų14.51%0.0057%0.074CC..Hα-helixtrans-58.6-46.7177-69.1171.3000111L153 L159 V282 F283 G288 L344 L352 L377 R380 L381 V384L153-L286 HydrophobicContact CD2-CB 4.33Å; L159-L286 HydrophobicContact CD1-CD1 4.29Å; L159-L286 HydrophobicContact CD2-CD1 4.45Å; V282-L286 HydrophobicContact CG1-CD1 4.3Å; V282-L286 WeakPolarHBondContact O-CG 3.5Å; V282-L286 PolarHBondContact O-N 3.48Å; V282-L286 VanDerWaalsContact O-N 3.08Å; F283-L286 WeakPolarHBondContact O-CB 3.47Å; F283-L286 PolarHBondContact O-N 3.15Å; L286-G288 VanDerWaalsContact C-N 3.34Å; L286-L344 HydrophobicContact CD1-CD2 4.46Å; L286-L352 HydrophobicContact CD2-CD2 4.3Å; L286-L377 HydrophobicContact CB-CD2 4.18Å; L286-L377 WeakPolarHBondContact O-CD2 3.43Å; L286-R380 HydrophobicContact CD2-CB 4.06Å; L286-R380 WeakPolarHBondContact O-CD 3.27Å; L286-R380 PolarHBondContact O-NH1 3.46Å; L286-L381 HydrophobicContact CD2-CB 4.03Å; L286-V384 HydrophobicContact CD2-CG2 4.37Å
287I97Very high96.1Very high0 Ų014.5 Ų14.50%07%0.074CC..Hα-helixtrans-80.3-16.3179.570.1178.5000112.8A150 L153 F283 D284 Y285 N289 N312 S315 F316 R380A150-I287 HydrophobicContact CB-CD1 4.41Å; L153-I287 HydrophobicContact CD2-CG2 3.31Å; F283-I287 HydrophobicContact CD1-CD1 3.97Å; F283-I287 HydrophobicContact CE1-CD1 3.52Å; F283-I287 HydrophobicContact CZ-CD1 4.13Å; F283-I287 HydrophobicContact CZ-CG2 4.43Å; F283-I287 PolarHBondContact O-N 2.98Å; F283-I287 VanDerWaalsContact O-N 3.13Å; D284-I287 WeakPolarHBondContact O-CG1 3.37Å; D284-I287 PolarHBondContact O-N 3.15Å; Y285-I287 VanDerWaalsContact C-N 3.34Å; Y285-I287 PolarHBondContact O-N 3.07Å; I287-N289 HydrophobicContact CD1-CB 3.78Å; I287-N289 HydrophobicContact CG1-CB 3.77Å; I287-N312 HydrophobicContact CD1-CB 4.26Å; I287-S315 VanDerWaalsContact CD1-CB 3.48Å; I287-S315 VanDerWaalsContact CG1-CB 3.43Å; I287-S315 WeakPolarHBondContact O-CB 3.26Å; I287-F316 HydrophobicContact CB-CD2 4.21Å; I287-F316 HydrophobicContact CB-CE1 4.41Å; I287-F316 HydrophobicContact CB-CE2 3.65Å; I287-F316 HydrophobicContact CB-CZ 3.78Å; I287-F316 HydrophobicContact CG2-CE1 4.46Å; I287-F316 HydrophobicContact CG2-CE2 3.66Å; I287-F316 HydrophobicContact CG2-CZ 3.55Å; I287-F316 PolarHBondContact O-N 3.25Å; I287-R380 PolarHBondContact O-NH1 3.43Å
288G97.4Very high95.9Very high18 Ų1814.5 Ų14.519%0.1867%0.074CC..THydrogen-bonded Turntrans73.939.2-175.300000113.2D284 Y285 L286D284-G288 CarbonylContact O-C 3.58Å; D284-G288 VanDerWaalsContact O-CA 3.31Å; D284-G288 WeakPolarHBondContact O-CA 3.18Å; D284-G288 PolarHBondContact O-N 3.26Å; Y285-G288 PolarHBondContact O-N 3.44Å; L286-G288 VanDerWaalsContact C-N 3.34Å
289N97.7Very high95.4Very high4 Ų419.4 Ų19.42%0.02110%0.097CC..  trans-90.199.8174.7-177.518.5000110.8D284 I287 D291 R292D284-N289 HydrophobicContact CB-CB 4.08Å; D284-N289 PolarHBondContact O-N 3.07Å; D284-N289 WeakPolarHBondContact OD1-CB 3.29Å; D284-N289 PolarHBondContact OD1-ND2 3.49Å; I287-N289 HydrophobicContact CD1-CB 3.78Å; I287-N289 HydrophobicContact CG1-CB 3.77Å; N289-D291 PolarHBondContact OD1-N 3.13Å; N289-R292 PolarHBondContact ND2-NH2 3.27Å
290A96.3Very high94.2Very high9 Ų922.3 Ų22.37%0.07411%0.112CC..  trans-93.47.817700000113.8P137 R242 E323 I326P137-A290 HydrophobicContact CB-CB 3.39Å; R242-A290 PolarHBondContact NE-O 3.39Å; R242-A290 VanDerWaalsContact NE-O 3.09Å; A290-E323 HydrophobicContact CB-CG 4.36Å; A290-I326 HydrophobicContact CB-CD1 4.07Å; A290-I326 HydrophobicContact CB-CG1 4.1Å
291D95.4Very high92.4Very high30 Ų3031 Ų3116%0.1616%0.158CC..  trans-108.414-170.4-158.929.1000113.9Y244 N289 H293 K314Y244-D291 WeakPolarHBondContact CE1-OD1 3.4Å; Y244-D291 PolarHBondContact OH-O 3.07Å; Y244-D291 PolarHBondContact OH-OD1 3.27Å; N289-D291 PolarHBondContact OD1-N 3.13Å; D291-H293 VanDerWaalsContact C-N 3.3Å; D291-H293 PolarHBondContact O-N 3.13Å; D291-H293 PolarHBondContact O-ND1 3.2Å; D291-H293 IonicContact OD1-ND1 3.37Å; D291-K314 HydrophobicContact CB-CB 3.88Å; D291-K314 HydrophobicContact CB-CG 4.13Å
292R95.7Very high90.7Very high23 Ų2333.9 Ų33.99%0.08719%0.189CC..  trans-78.374.5177.2-164.3175.9-59-77.1-0.9112.5H238 D284 N289 H294 L310 N312H238-R292 WeakPolarHBondContact CB-O 3.34Å; D284-R292 VanDerWaalsContact CG-NE 3.33Å; D284-R292 IonicContact OD1-CZ 3.59Å; D284-R292 IonicContact OD1-NE 2.92Å; D284-R292 PolarHBondContact OD1-NE 2.96Å; D284-R292 IonicContact OD1-NH2 2.74Å; D284-R292 PolarHBondContact OD1-NH2 3.26Å; D284-R292 VanDerWaalsContact OD2-CD 3.26Å; D284-R292 WeakPolarHBondContact OD2-CD 3.47Å; D284-R292 IonicContact OD2-CZ 3.66Å; D284-R292 IonicContact OD2-NE 2.75Å; D284-R292 PolarHBondContact OD2-NE 3.25Å; D284-R292 IonicContact OD2-NH2 2.7Å; N289-R292 PolarHBondContact ND2-NH2 3.27Å; R292-H294 WeakPolarHBondContact CG-O 3.4Å; R292-L310 PolarHBondContact NH1-O 2.91Å; R292-N312 PolarHBondContact NH2-OD1 2.96Å
293H93.8Very high89.2Confident70 Ų7036.1 Ų36.132%0.32421%0.212SC..SBendtrans-87.6-19.8179.555.5-73.7000114.2H238 Y244 D291H238-H293 WeakPolarHBondContact CB-O 3.09Å; H238-H293 PolarHBondContact N-O 3.37Å; Y244-H293 HydrophobicContact CE2-CB 3.58Å; Y244-H293 AromaticContact CE2-CG 3.93Å; Y244-H293 AromaticContact CZ-CG 3.96Å; Y244-H293 AromaticContact CZ-ND1 3.96Å; Y244-H293 VanDerWaalsContact OH-CB 3.28Å; Y244-H293 WeakPolarHBondContact OH-CB 3.46Å; Y244-H293 PolarHBondContact OH-ND1 3Å; D291-H293 VanDerWaalsContact C-N 3.3Å; D291-H293 PolarHBondContact O-N 3.13Å; D291-H293 PolarHBondContact O-ND1 3.2Å; D291-H293 IonicContact OD1-ND1 3.37Å
294H94.4Very high88Confident68 Ų6837.9 Ų37.932%0.31523%0.227SC..EExtended strand (participates in β ladder)trans-129.6158.7165.2-64.386.7000108.7K235 H236 R292K235-H294 HydrophobicContact CD-CB 4.46Å; K235-H294 VanDerWaalsContact CE-CB 3.49Å; K235-H294 WeakPolarHBondContact CE-CD2 3.37Å; K235-H294 HydrophobicContact CG-CB 4.14Å; H236-H294 WeakPolarHBondContact O-CA 3.37Å; H236-H294 VanDerWaalsContact O-CB 3.28Å; H236-H294 WeakPolarHBondContact O-CB 3.44Å; H236-H294 PolarHBondContact O-CD2 2.57Å; R292-H294 WeakPolarHBondContact CG-O 3.4Å
295Y94.3Very high87.2Confident4 Ų437.8 Ų37.82%0.01623%0.226CC..EExtended strand (participates in β ladder)trans-131.7162.2165.866.8-99.4000109H236 H238 Y268 R273 V277 L307H236-Y295 HydrophobicContact CB-CD1 4.3Å; H236-Y295 HydrophobicContact CB-CD2 3.91Å; H236-Y295 HydrophobicContact CB-CE1 3.84Å; H236-Y295 HydrophobicContact CB-CE2 3.33Å; H236-Y295 HydrophobicContact CB-CG 4.35Å; H236-Y295 AromaticContact CD2-CE2 3.5Å; H236-Y295 VanDerWaalsContact CD2-CE2 3.5Å; H236-Y295 WeakPolarHBondContact CD2-CE2 3.39Å; H236-Y295 AromaticContact CG-CE2 3.52Å; H236-Y295 AromaticContact CG-CZ 3.83Å; H236-Y295 PolarHBondContact N-O 2.7Å; H236-Y295 PolarHBondContact O-N 3Å; H238-Y295 HydrophobicContact CB-CD1 4.34Å; H238-Y295 AromaticContact CD2-CD1 3.81Å; Y268-Y295 HydrophobicContact CE1-CE1 4.45Å; Y268-Y295 WeakPolarHBondContact CE1-OH 3.4Å; Y268-Y295 WeakPolarHBondContact OH-CE1 3.35Å; Y268-Y295 PolarHBondContact OH-OH 3.42Å; R273-Y295 VanDerWaalsContact NH1-CE2 3.26Å; V277-Y295 HydrophobicContact CG2-CE1 4.31Å; Y295-L307 HydrophobicContact CD1-CD1 3.97Å; Y295-L307 HydrophobicContact CD2-CB 4.49Å; Y295-L307 HydrophobicContact CD2-CD1 3.71Å; Y295-L307 HydrophobicContact CD2-CG 3.63Å; Y295-L307 HydrophobicContact CE2-CD1 4.34Å; Y295-L307 HydrophobicContact CE2-CG 4.47Å; Y295-L307 HydrophobicContact CG-CD1 3.5Å; Y295-L307 HydrophobicContact CG-CG 3.77Å
296E93.4Very high86.7Confident50 Ų5037 Ų3723%0.23422%0.223CC..EExtended strand (participates in β ladder)trans-117.7150.1178.3-60.1-172.5174.400109.9L233 Q234 K235 I308 L310L233-E296 HydrophobicContact CB-CB 4.5Å; L233-E296 VanDerWaalsContact CD1-OE2 3.3Å; L233-E296 WeakPolarHBondContact CD1-OE2 3.44Å; Q234-E296 CarbonylContact O-C 3.5Å; Q234-E296 VanDerWaalsContact O-CA 3.24Å; Q234-E296 WeakPolarHBondContact O-CA 3.41Å; K235-E296 HydrophobicContact CB-CG 4.46Å; E296-I308 PolarHBondContact O-N 2.83Å; E296-L310 HydrophobicContact CB-CD1 4.13Å; E296-L310 HydrophobicContact CG-CD1 4.41Å; E296-L310 WeakPolarHBondContact OE2-CD1 3.35Å
297S92.4Very high86.5Confident0 Ų036.9 Ų36.90%022%0.223CC..EExtended strand (participates in β ladder)trans-137.1160.7169.862.50000109.2L233 Q234 H236 R273 M306L233-S297 CarbonylContact C-O 3.52Å; Q234-S297 PolarHBondContact N-O 3.35Å; Q234-S297 PolarHBondContact O-N 2.87Å; H236-S297 PolarHBondContact CD2-OG 3.35Å; H236-S297 PolarHBondContact NE2-OG 2.81Å; R273-S297 PolarHBondContact NH1-OG 3.16Å; R273-S297 PolarHBondContact NH2-OG 3.43Å; S297-M306 WeakPolarHBondContact CA-O 3.2Å; S297-M306 WeakPolarHBondContact CB-O 3.28Å
298F90.8Very high86.3Confident0 Ų036.9 Ų36.90%022%0.223CC..EExtended strand (participates in β ladder)trans-61.9141.4168.1-59.7-51.2000110.4V71 G72 L227 W231 L233 D300 S305 M306 I308V71-F298 HydrophobicContact CG1-CE1 4.27Å; V71-F298 HydrophobicContact CG1-CE2 3.95Å; V71-F298 HydrophobicContact CG1-CZ 3.49Å; V71-F298 VanDerWaalsContact CG1-CZ 3.49Å; G72-F298 VanDerWaalsContact O-CE2 3.29Å; G72-F298 WeakPolarHBondContact O-CE2 3.3Å; L227-F298 HydrophobicContact CD1-CE1 4Å; L227-F298 HydrophobicContact CD1-CZ 4.28Å; W231-F298 HydrophobicContact CB-CD1 3.61Å; W231-F298 HydrophobicContact CB-CE1 3.58Å; W231-F298 HydrophobicContact CB-CG 4.35Å; W231-F298 HydrophobicContact CB-CZ 4.3Å; W231-F298 HydrophobicContact CD2-CG 4.47Å; W231-F298 HydrophobicContact CE3-CB 3.99Å; W231-F298 HydrophobicContact CE3-CD1 4.3Å; W231-F298 HydrophobicContact CE3-CD2 4.09Å; W231-F298 AromaticContact CE3-CG 3.87Å; W231-F298 HydrophobicContact CE3-CG 3.87Å; W231-F298 HydrophobicContact CG-CD1 4.35Å; W231-F298 HydrophobicContact CG-CE1 4.27Å; L233-F298 HydrophobicContact CD2-CD1 3.76Å; L233-F298 HydrophobicContact CD2-CE1 3.8Å; F298-D300 PolarHBondContact O-N 3.38Å; F298-S305 WeakPolarHBondContact O-CB 3.28Å; F298-S305 PolarHBondContact O-OG 3.17Å; F298-M306 HydrophobicContact CE2-CE 4.1Å; F298-I308 HydrophobicContact CD2-CD1 3.91Å; F298-I308 HydrophobicContact CE1-CD1 4.12Å; F298-I308 HydrophobicContact CE1-CG1 4.32Å; F298-I308 HydrophobicContact CE2-CD1 3.42Å; F298-I308 VanDerWaalsContact CE2-CD1 3.42Å; F298-I308 HydrophobicContact CE2-CG1 4.4Å; F298-I308 HydrophobicContact CG-CD1 4.45Å; F298-I308 HydrophobicContact CZ-CD1 3.55Å; F298-I308 HydrophobicContact CZ-CG1 4.21Å
299Q86.4Confident86.1Confident105 Ų10536.1 Ų36.149%0.49121%0.214SC..  trans-66.5118.6165.5-65.7175.821.600106.9P232 L233 Q234P232-Q299 HydrophobicContact CG-CB 4.16Å; P232-Q299 HydrophobicContact CG-CG 4.45Å; P232-Q299 PolarHBondContact O-N 3.25Å; L233-Q299 PolarHBondContact O-NE2 2.8Å; L233-Q299 VanDerWaalsContact O-NE2 3.1Å; Q234-Q299 HydrophobicContact CB-CG 3.75Å; Q234-Q299 HydrophobicContact CG-CG 4.48Å
300D70.8Confident85.9Confident61 Ų6137.5 Ų37.533%0.32622%0.221SC..  trans-139.3132.9-177.9160.624.2000107F298 G302 G303 A304 S305F298-D300 PolarHBondContact O-N 3.38Å; D300-G302 PolarHBondContact O-N 3.02Å; D300-G302 PolarHBondContact OD1-N 3.06Å; D300-G303 PolarHBondContact OD2-N 2.86Å; D300-A304 PolarHBondContact OD2-N 2.82Å; D300-S305 PolarHBondContact OD2-N 3.45Å
301D57.9Low85.5Confident182 Ų18241.6 Ų41.697%0.97324%0.242SC*.THydrogen-bonded Turntrans-69.7-12.8-179.2-65.6-32.7000113.1
302G62.8Low85.6Confident63 Ų6340.3 Ų40.365%0.64924%0.235SC*.THydrogen-bonded Turntrans-108.2-0.6-177.500000116.2D300 A304D300-G302 PolarHBondContact O-N 3.02Å; D300-G302 PolarHBondContact OD1-N 3.06Å; G302-A304 PolarHBondContact O-N 3.27Å; G302-A304 VanDerWaalsContact O-N 3.13Å
303G65.3Low85.6Confident48 Ų4839.2 Ų39.250%0.49523%0.231SC..SBendtrans65.412.4178.200000115.3D300D300-G303 PolarHBondContact OD2-N 2.86Å
304A72Confident85.7Confident37 Ų3736.9 Ų36.931%0.30622%0.22SC..  trans-90.3-11.1-179.700000112.4R74 D300 G302 M306R74-A304 WeakPolarHBondContact CD-O 3.36Å; R74-A304 PolarHBondContact NH1-O 3.37Å; D300-A304 PolarHBondContact OD2-N 2.82Å; G302-A304 PolarHBondContact O-N 3.27Å; G302-A304 VanDerWaalsContact O-N 3.13Å; A304-M306 PolarHBondContact O-N 2.91Å
305S82.4Confident85.8Confident3 Ų333.7 Ų33.72%0.02121%0.205CC..PPolyproline II helixtrans-52.6137.8-179.7660000113R273 F298 D300R273-S305 PolarHBondContact NH2-O 3.09Å; R273-S305 PolarHBondContact NH2-OG 2.74Å; F298-S305 WeakPolarHBondContact O-CB 3.28Å; F298-S305 PolarHBondContact O-OG 3.17Å; D300-S305 PolarHBondContact OD2-N 3.45Å
306M87.7Confident85.9Confident0 Ų033.7 Ų33.70%021%0.205CC..PPolyproline II helixtrans-75.3159.8178.270.4174.9173.300112.5P73 R74 E75 V76 R163 S297 F298 A304 I308P73-M306 WeakPolarHBondContact O-CG 3.45Å; P73-M306 PolarHBondContact O-N 2.76Å; R74-M306 VanDerWaalsContact NH1-CA 3.3Å; E75-M306 VanDerWaalsContact CA-CE 3.41Å; V76-M306 HydrophobicContact CG2-CE 3.63Å; R163-M306 HydrophobicContact CB-CE 4.43Å; R163-M306 HydrophobicContact CB-SD 4.06Å; R163-M306 HydrophobicContact CG-CE 4.46Å; R163-M306 HydrophobicContact CG-SD 3.56Å; R163-M306 VanDerWaalsContact CG-SD 3.56Å; S297-M306 WeakPolarHBondContact CA-O 3.2Å; S297-M306 WeakPolarHBondContact CB-O 3.28Å; F298-M306 HydrophobicContact CE2-CE 4.1Å; A304-M306 PolarHBondContact O-N 2.91Å; M306-I308 HydrophobicContact CE-CD1 3.56Å; M306-I308 HydrophobicContact CG-CD1 3.79Å; M306-I308 HydrophobicContact SD-CD1 4.39Å
307L91.8Very high86.1Confident0 Ų031.8 Ų31.80%020%0.199CC..EExtended strand (participates in β ladder)trans-73.5123.1166.8-169.2162.6000109.7R163 D276 V277 T280 Y295 L309R163-L307 WeakPolarHBondContact CB-O 3.42Å; R163-L307 WeakPolarHBondContact CD-O 3.22Å; D276-L307 HydrophobicContact CB-CB 4.15Å; V277-L307 HydrophobicContact CG2-CD1 4.13Å; T280-L307 HydrophobicContact CG2-CD1 4.36Å; T280-L307 HydrophobicContact CG2-CD2 3.99Å; T280-L307 WeakPolarHBondContact OG1-CD2 3.43Å; Y295-L307 HydrophobicContact CD1-CD1 3.97Å; Y295-L307 HydrophobicContact CD2-CB 4.49Å; Y295-L307 HydrophobicContact CD2-CD1 3.71Å; Y295-L307 HydrophobicContact CD2-CG 3.63Å; Y295-L307 HydrophobicContact CE2-CD1 4.34Å; Y295-L307 HydrophobicContact CE2-CG 4.47Å; Y295-L307 HydrophobicContact CG-CD1 3.5Å; Y295-L307 HydrophobicContact CG-CG 3.77Å; L307-L309 HydrophobicContact CD2-CD2 4.14Å
308I93.2Very high86.3Confident0 Ų033.5 Ų33.50%021%0.208CC..EExtended strand (participates in β ladder)trans-87.5129.3177.9-47.1-58000110.2R163 L227 L233 E296 F298 M306 L310R163-I308 WeakPolarHBondContact O-CA 3.46Å; R163-I308 WeakPolarHBondContact O-CG2 3.37Å; L227-I308 HydrophobicContact CD1-CG2 4.05Å; L233-I308 HydrophobicContact CD2-CG1 4.15Å; E296-I308 PolarHBondContact O-N 2.83Å; F298-I308 HydrophobicContact CD2-CD1 3.91Å; F298-I308 HydrophobicContact CE1-CD1 4.12Å; F298-I308 HydrophobicContact CE1-CG1 4.32Å; F298-I308 HydrophobicContact CE2-CD1 3.42Å; F298-I308 VanDerWaalsContact CE2-CD1 3.42Å; F298-I308 HydrophobicContact CE2-CG1 4.4Å; F298-I308 HydrophobicContact CG-CD1 4.45Å; F298-I308 HydrophobicContact CZ-CD1 3.55Å; F298-I308 HydrophobicContact CZ-CG1 4.21Å; M306-I308 HydrophobicContact CE-CD1 3.56Å; M306-I308 HydrophobicContact CG-CD1 3.79Å; M306-I308 HydrophobicContact SD-CD1 4.39Å; I308-L310 VanDerWaalsContact C-N 3.28Å; I308-L310 HydrophobicContact CB-CD1 4.48Å; I308-L310 HydrophobicContact CB-CG 4.21Å; I308-L310 HydrophobicContact CG2-CD1 4.15Å; I308-L310 HydrophobicContact CG2-CD2 3.79Å; I308-L310 HydrophobicContact CG2-CG 3.64Å; I308-L310 PolarHBondContact O-N 2.55Å
309L93.9Very high86.6Confident1 Ų134 Ų341%0.00521%0.212CC..  trans-8272.4-179.7-65.2176.1000110.8D154 R163 A164 T280 F283 L307 N312D154-L309 HydrophobicContact CB-CD1 4.37Å; D154-L309 WeakPolarHBondContact OD1-CD1 3.49Å; R163-L309 HydrophobicContact CB-CB 4.46Å; R163-L309 HydrophobicContact CB-CD1 4.08Å; R163-L309 HydrophobicContact CB-CG 3.91Å; R163-L309 PolarHBondContact O-N 3.48Å; A164-L309 HydrophobicContact CB-CB 4.1Å; T280-L309 HydrophobicContact CG2-CD2 3.61Å; F283-L309 HydrophobicContact CD1-CD1 3.9Å; F283-L309 HydrophobicContact CD1-CD2 3.96Å; F283-L309 HydrophobicContact CD1-CG 4.5Å; F283-L309 HydrophobicContact CD2-CD1 4.17Å; F283-L309 HydrophobicContact CE1-CD1 3.9Å; F283-L309 HydrophobicContact CE1-CD2 4.29Å; F283-L309 HydrophobicContact CE1-CG 4.48Å; F283-L309 HydrophobicContact CE2-CD1 4.18Å; F283-L309 HydrophobicContact CG-CD1 4.02Å; F283-L309 HydrophobicContact CZ-CD1 4.03Å; L307-L309 HydrophobicContact CD2-CD2 4.14Å; L309-N312 PolarHBondContact O-ND2 2.8Å
310L92.4Very high87.1Confident33 Ų3334 Ų3417%0.17322%0.223CC..  trans-91.7157.8174.3-59.4176.3000112P165 L233 R292 E296 I308P165-L310 HydrophobicContact CG-CD2 3.64Å; L233-L310 HydrophobicContact CD1-CD1 3.81Å; R292-L310 PolarHBondContact NH1-O 2.91Å; E296-L310 HydrophobicContact CB-CD1 4.13Å; E296-L310 HydrophobicContact CG-CD1 4.41Å; E296-L310 WeakPolarHBondContact OE2-CD1 3.35Å; I308-L310 VanDerWaalsContact C-N 3.28Å; I308-L310 HydrophobicContact CB-CD1 4.48Å; I308-L310 HydrophobicContact CB-CG 4.21Å; I308-L310 HydrophobicContact CG2-CD1 4.15Å; I308-L310 HydrophobicContact CG2-CD2 3.79Å; I308-L310 HydrophobicContact CG2-CG 3.64Å; I308-L310 PolarHBondContact O-N 2.55Å
311D89.4Confident88.3Confident96 Ų9635.3 Ų35.351%0.51323%0.23SC..  trans52.163174.9-75.9-40.1000113.8K123K123-D311 IonicContact NZ-OD1 3.64Å; K123-D311 PolarHBondContact NZ-OD1 2.82Å
312N95.9Very high90.2Very high3 Ų328.7 Ų28.72%0.01619%0.194CC..  trans-92.14.2-179.8-51.2-65.9000112.9E147 A150 I287 R292 L309 K314 S315E147-N312 PolarHBondContact OE1-N 2.86Å; E147-N312 VanDerWaalsContact OE1-N 3.13Å; E147-N312 WeakPolarHBondContact OE2-CB 3.33Å; E147-N312 PolarHBondContact OE2-N 3.25Å; A150-N312 HydrophobicContact CB-CB 3.37Å; I287-N312 HydrophobicContact CD1-CB 4.26Å; R292-N312 PolarHBondContact NH2-OD1 2.96Å; L309-N312 PolarHBondContact O-ND2 2.8Å; N312-K314 PolarHBondContact O-N 2.91Å; N312-K314 VanDerWaalsContact O-N 3.09Å; N312-S315 VanDerWaalsContact O-CB 3.25Å; N312-S315 WeakPolarHBondContact O-CB 3.08Å; N312-S315 PolarHBondContact O-N 2.71Å; N312-S315 VanDerWaalsContact O-N 3.08Å; N312-S315 PolarHBondContact O-OG 3.44Å
313A96.1Very high91.8Very high0 Ų028 Ų280%017%0.174CC..THydrogen-bonded Turntrans-61.3-18.1-177.400000115K123 D142 R143 E147 S315K123-A313 HydrophobicContact CD-CB 4.01Å; D142-A313 HydrophobicContact CB-CB 3.51Å; D142-A313 WeakPolarHBondContact OD2-CB 3.44Å; R143-A313 PolarHBondContact N-O 3.18Å; E147-A313 HydrophobicContact CG-CB 3.74Å; E147-A313 VanDerWaalsContact OE1-CB 3.25Å; E147-A313 WeakPolarHBondContact OE1-CB 3.43Å; E147-A313 PolarHBondContact OE1-N 2.92Å; A313-S315 PolarHBondContact O-N 2.98Å
314K95.9Very high93.3Very high21 Ų2132.9 Ų32.99%0.09118%0.178CC..THydrogen-bonded Turntrans-84.116.5174.9-69.4-74.2-162.1155.20113.5Y138 G140 D142 R143 D291 N312Y138-K314 PolarHBondContact O-NZ 3.27Å; G140-K314 PolarHBondContact O-NZ 3.19Å; D142-K314 WeakPolarHBondContact OD1-CE 3.46Å; R143-K314 PolarHBondContact NH2-O 2.77Å; D291-K314 HydrophobicContact CB-CB 3.88Å; D291-K314 HydrophobicContact CB-CG 4.13Å; N312-K314 PolarHBondContact O-N 2.91Å; N312-K314 VanDerWaalsContact O-N 3.09Å
315S96.8Very high94.4Very high0 Ų032.3 Ų32.30%017%0.172CC..  trans-103174.5175.468.20000113.2R143 A146 I287 N312 A313 G317R143-S315 VanDerWaalsContact CZ-O 3.22Å; R143-S315 PolarHBondContact NE-O 2.9Å; R143-S315 PolarHBondContact NH2-O 3.08Å; A146-S315 WeakPolarHBondContact CB-O 3.38Å; A146-S315 WeakPolarHBondContact CB-OG 3.3Å; I287-S315 VanDerWaalsContact CD1-CB 3.48Å; I287-S315 VanDerWaalsContact CG1-CB 3.43Å; I287-S315 WeakPolarHBondContact O-CB 3.26Å; N312-S315 VanDerWaalsContact O-CB 3.25Å; N312-S315 WeakPolarHBondContact O-CB 3.08Å; N312-S315 PolarHBondContact O-N 2.71Å; N312-S315 VanDerWaalsContact O-N 3.08Å; N312-S315 PolarHBondContact O-OG 3.44Å; A313-S315 PolarHBondContact O-N 2.98Å; S315-G317 PolarHBondContact O-N 3.34Å
316F97.2Very high95.2Very high4 Ų433 Ų332%0.01818%0.175CC..SBendtrans51.738.3-179.3-58-79.5000113.9A146 A149 I287 L369 H373 L377A146-F316 HydrophobicContact CB-CB 4.36Å; A146-F316 HydrophobicContact CB-CD2 3.93Å; A149-F316 HydrophobicContact CB-CD2 4.12Å; A149-F316 HydrophobicContact CB-CE2 3.58Å; A149-F316 HydrophobicContact CB-CZ 3.98Å; I287-F316 HydrophobicContact CB-CD2 4.21Å; I287-F316 HydrophobicContact CB-CE1 4.41Å; I287-F316 HydrophobicContact CB-CE2 3.65Å; I287-F316 HydrophobicContact CB-CZ 3.78Å; I287-F316 HydrophobicContact CG2-CE1 4.46Å; I287-F316 HydrophobicContact CG2-CE2 3.66Å; I287-F316 HydrophobicContact CG2-CZ 3.55Å; I287-F316 PolarHBondContact O-N 3.25Å; F316-L369 HydrophobicContact CB-CD2 4.15Å; F316-L369 HydrophobicContact CD1-CD1 4.1Å; F316-L369 HydrophobicContact CD1-CD2 3.8Å; F316-L369 HydrophobicContact CD2-CD2 4.15Å; F316-L369 HydrophobicContact CE1-CD1 3.68Å; F316-L369 HydrophobicContact CE1-CD2 4.18Å; F316-L369 HydrophobicContact CG-CD2 3.77Å; F316-L369 HydrophobicContact CZ-CD1 3.99Å; F316-H373 VanDerWaalsContact C-CE1 3.45Å; F316-H373 HydrophobicContact CD1-CB 4.17Å; F316-H373 AromaticContact CD1-ND1 3.92Å; F316-H373 PolarHBondContact O-CE1 3.48Å; F316-H373 PolarHBondContact O-NE2 3.2Å; F316-L377 HydrophobicContact CE1-CD1 4.4Å; F316-L377 HydrophobicContact CE1-CD2 4.04Å; F316-L377 HydrophobicContact CE1-CG 4.31Å; F316-L377 HydrophobicContact CZ-CD2 4.38Å
317G96.9Very high95.6Very high10 Ų1033.1 Ų33.110%0.10318%0.175CC..SBendtrans-82.4-36.5178.800000113.7V133 S315V133-G317 PolarHBondContact N-O 2.8Å; S315-G317 PolarHBondContact O-N 3.34Å
318N97.4Very high95.9Very high37 Ų3733.1 Ų33.120%0.19818%0.175CC..  trans-139.4117.9-177.2-168.4-37.2000110.1V132 V133 S320 L321 R380V132-N318 HydrophobicContact CG1-CB 4.16Å; V132-N318 WeakPolarHBondContact CG1-ND2 3.41Å; V133-N318 PolarHBondContact O-ND2 2.76Å; N318-S320 VanDerWaalsContact C-N 3.33Å; N318-S320 WeakPolarHBondContact OD1-CA 3.46Å; N318-S320 WeakPolarHBondContact OD1-CB 3.32Å; N318-S320 PolarHBondContact OD1-N 3.48Å; N318-L321 HydrophobicContact CB-CB 4.25Å; N318-L321 PolarHBondContact OD1-N 2.79Å; N318-R380 PolarHBondContact O-NH2 3.3Å
319P97.1Very high96.2Very high10 Ų1033.2 Ų33.27%0.06518%0.176CC..SBendtrans-80.6-13.1179.231.1-33000113.4P372 A376 R379P319-P372 HydrophobicContact CB-CB 3.67Å; P319-P372 HydrophobicContact CG-CB 3.82Å; P319-A376 HydrophobicContact CB-CB 4.45Å; P319-A376 WeakPolarHBondContact O-CB 3.32Å; P319-R379 PolarHBondContact O-NH1 3.22Å; P319-R379 PolarHBondContact O-NH2 2.88Å
320S96.7Very high96.3Very high104 Ų10433.2 Ų33.273%0.72718%0.176SC*.SBendtrans-99.3-11.3-175.5-580000113.4N318N318-S320 VanDerWaalsContact C-N 3.33Å; N318-S320 WeakPolarHBondContact OD1-CA 3.46Å; N318-S320 WeakPolarHBondContact OD1-CB 3.32Å; N318-S320 PolarHBondContact OD1-N 3.48Å
321L95.7Very high96.6Very high90 Ų9035.2 Ų35.247%0.47118%0.182SC..  trans-111.9131.3179.2-176.966.7000110.8N318 R380N318-L321 HydrophobicContact CB-CB 4.25Å; N318-L321 PolarHBondContact OD1-N 2.79Å; L321-R380 PolarHBondContact O-NH2 2.95Å
322D96.8Very high96.9Very high43 Ų4332 Ų3223%0.2316%0.164CC..  trans-114.4100.3174.1-60.4-27.4000109.2Y285 R324 R379 R380Y285-D322 HydrophobicContact CE2-CB 4.38Å; D322-R324 PolarHBondContact O-N 3.18Å; D322-R379 IonicContact OD1-CZ 3.33Å; D322-R379 IonicContact OD1-NE 2.77Å; D322-R379 IonicContact OD1-NH2 3.38Å; D322-R379 PolarHBondContact OD1-NH2 2.9Å; D322-R379 IonicContact OD2-CZ 2.82Å; D322-R379 IonicContact OD2-NE 3.23Å; D322-R379 PolarHBondContact OD2-NE 3.45Å; D322-R379 IonicContact OD2-NH2 2.94Å; D322-R379 PolarHBondContact OD2-NH2 3.06Å; D322-R380 HydrophobicContact CB-CG 4.3Å; D322-R380 VanDerWaalsContact OD1-CG 3.23Å; D322-R380 WeakPolarHBondContact OD1-CG 3.34Å; D322-R380 IonicContact OD1-CZ 2.95Å; D322-R380 IonicContact OD1-NE 2.97Å; D322-R380 PolarHBondContact OD1-NE 3.44Å; D322-R380 IonicContact OD1-NH2 3.8Å
323E96.8Very high97Very high48 Ų4831.9 Ų31.922%0.22416%0.163CC..  trans-7589.9-173.4-178.551.2-108.600111.6P137 Y285 A290 S325 I326P137-E323 HydrophobicContact CB-CG 4.25Å; P137-E323 HydrophobicContact CG-CG 4.35Å; P137-E323 WeakPolarHBondContact CG-OE2 3.41Å; Y285-E323 WeakPolarHBondContact CD2-O 3.28Å; A290-E323 HydrophobicContact CB-CG 4.36Å; E323-S325 VanDerWaalsContact CD-OG 3.23Å; E323-S325 WeakPolarHBondContact CG-OG 3.47Å; E323-S325 PolarHBondContact O-N 2.94Å; E323-S325 VanDerWaalsContact O-N 3.15Å; E323-S325 VanDerWaalsContact OE1-CB 3.32Å; E323-S325 WeakPolarHBondContact OE1-CB 3.33Å; E323-S325 PolarHBondContact OE1-N 3.37Å; E323-S325 PolarHBondContact OE1-OG 2.99Å; E323-I326 HydrophobicContact CB-CD1 3.83Å; E323-I326 HydrophobicContact CB-CG1 4.19Å; E323-I326 HydrophobicContact CG-CD1 4.07Å; E323-I326 HydrophobicContact CG-CG1 3.93Å; E323-I326 PolarHBondContact O-N 3.41Å; E323-I326 VanDerWaalsContact O-N 3.15Å
324R96.2Very high97Very high150 Ų15032.4 Ų32.457%0.56617%0.167SC*.G310 helixtrans-56.7-30.6-176.4-175.6177.9179.4-168.20.3113.1D322 I326 L327D322-R324 PolarHBondContact O-N 3.18Å; R324-I326 PolarHBondContact O-N 2.86Å; R324-I326 VanDerWaalsContact O-N 3.14Å; R324-L327 PolarHBondContact O-N 2.93Å
325S96.4Very high97Very high26 Ų2632.8 Ų32.818%0.18217%0.169CC..G310 helixtrans-63.5-19.3-178.462.70000113.6R242 E323 L327 A328R242-S325 PolarHBondContact NH2-OG 2.88Å; E323-S325 VanDerWaalsContact CD-OG 3.23Å; E323-S325 WeakPolarHBondContact CG-OG 3.47Å; E323-S325 PolarHBondContact O-N 2.94Å; E323-S325 VanDerWaalsContact O-N 3.15Å; E323-S325 VanDerWaalsContact OE1-CB 3.32Å; E323-S325 WeakPolarHBondContact OE1-CB 3.33Å; E323-S325 PolarHBondContact OE1-N 3.37Å; E323-S325 PolarHBondContact OE1-OG 2.99Å; S325-L327 PolarHBondContact O-N 2.96Å; S325-A328 VanDerWaalsContact O-CB 3.25Å; S325-A328 WeakPolarHBondContact O-CB 3.44Å; S325-A328 PolarHBondContact O-N 3.33Å
326I98.1Very high96.9Very high17 Ų1732.8 Ų32.89%0.08717%0.169CC..G310 helixtrans-63.2-33.1171.8-58.8166.6000111.1D284 Y285 A290 E323 R324 A328 P329D284-I326 HydrophobicContact CB-CG2 3.61Å; Y285-I326 HydrophobicContact CD2-CB 4.28Å; A290-I326 HydrophobicContact CB-CD1 4.07Å; A290-I326 HydrophobicContact CB-CG1 4.1Å; E323-I326 HydrophobicContact CB-CD1 3.83Å; E323-I326 HydrophobicContact CB-CG1 4.19Å; E323-I326 HydrophobicContact CG-CD1 4.07Å; E323-I326 HydrophobicContact CG-CG1 3.93Å; E323-I326 PolarHBondContact O-N 3.41Å; E323-I326 VanDerWaalsContact O-N 3.15Å; R324-I326 PolarHBondContact O-N 2.86Å; R324-I326 VanDerWaalsContact O-N 3.14Å; I326-A328 PolarHBondContact O-N 2.88Å; I326-P329 VanDerWaalsContact O-CD 3.31Å; I326-P329 WeakPolarHBondContact O-CD 3.04Å
327L97.9Very high96.7Very high2 Ų233.4 Ų33.41%0.0117%0.172CC..G310 helixtrans-78.37.5177.8-69.4-179.7000113.9V282 Y285 R324 S325 P329 L330 Y331 V384V282-L327 HydrophobicContact CG2-CD2 4.45Å; Y285-L327 HydrophobicContact CD1-CD1 3.65Å; Y285-L327 HydrophobicContact CD1-CD2 3.94Å; Y285-L327 HydrophobicContact CD1-CG 3.83Å; Y285-L327 HydrophobicContact CD2-CD1 4.02Å; Y285-L327 HydrophobicContact CD2-CD2 4.41Å; Y285-L327 HydrophobicContact CD2-CG 3.7Å; Y285-L327 HydrophobicContact CE1-CD1 3.65Å; Y285-L327 HydrophobicContact CE1-CG 4.28Å; Y285-L327 HydrophobicContact CE2-CD1 4.05Å; Y285-L327 HydrophobicContact CE2-CG 4.2Å; Y285-L327 HydrophobicContact CG-CD1 3.81Å; Y285-L327 HydrophobicContact CG-CD2 3.71Å; Y285-L327 HydrophobicContact CG-CG 3.47Å; Y285-L327 VanDerWaalsContact CG-CG 3.47Å; R324-L327 PolarHBondContact O-N 2.93Å; S325-L327 PolarHBondContact O-N 2.96Å; L327-P329 VanDerWaalsContact C-CD 3.46Å; L327-P329 VanDerWaalsContact C-N 3.35Å; L327-L330 HydrophobicContact CD2-CD2 4.16Å; L327-L330 WeakPolarHBondContact O-CA 3.3Å; L327-L330 WeakPolarHBondContact O-CB 3.39Å; L327-L330 PolarHBondContact O-N 2.85Å; L327-Y331 HydrophobicContact CB-CD1 4.09Å; L327-Y331 WeakPolarHBondContact O-CD1 3.31Å; L327-Y331 PolarHBondContact O-N 2.82Å; L327-V384 HydrophobicContact CD1-CG2 4.3Å; L327-V384 HydrophobicContact CD2-CG2 4.23Å
328A97.8Very high96.5Very high0 Ų034.8 Ų34.80%018%0.178CC..Hα-helixtrans-50.5-44.6178.500000114.6W240 W252 S325 I326 L330 Y331 Q332W240-A328 HydrophobicContact CG-CB 4.49Å; W252-A328 HydrophobicContact CE3-CB 3.77Å; W252-A328 HydrophobicContact CZ3-CB 3.88Å; S325-A328 VanDerWaalsContact O-CB 3.25Å; S325-A328 WeakPolarHBondContact O-CB 3.44Å; S325-A328 PolarHBondContact O-N 3.33Å; I326-A328 PolarHBondContact O-N 2.88Å; A328-L330 VanDerWaalsContact C-N 3.27Å; A328-L330 PolarHBondContact O-N 2.83Å; A328-Y331 VanDerWaalsContact CA-CZ 3.4Å; A328-Y331 HydrophobicContact CB-CE1 3.93Å; A328-Y331 HydrophobicContact CB-CE2 4.41Å; A328-Y331 WeakPolarHBondContact CB-OH 3.34Å; A328-Y331 VanDerWaalsContact N-CE1 3.3Å; A328-Q332 WeakPolarHBondContact O-CB 3.33Å; A328-Q332 VanDerWaalsContact O-CG 3.27Å; A328-Q332 WeakPolarHBondContact O-CG 3.33Å; A328-Q332 PolarHBondContact O-N 3.48Å
329P97.9Very high96Very high3 Ų335.4 Ų35.42%0.01919%0.185CC..Hα-helixtrans-57.8-40.2174.4-23.634.5000112.6W240 V277 I278 A281 I326 L327 C333W240-P329 HydrophobicContact CB-CG 4.2Å; W240-P329 HydrophobicContact CD2-CB 4.11Å; W240-P329 HydrophobicContact CD2-CG 3.59Å; W240-P329 HydrophobicContact CE3-CB 4.09Å; W240-P329 HydrophobicContact CE3-CG 3.77Å; W240-P329 HydrophobicContact CG-CG 3.76Å; W240-P329 HydrophobicContact CH2-CB 4.36Å; W240-P329 HydrophobicContact CZ2-CB 4.35Å; W240-P329 HydrophobicContact CZ3-CB 4.23Å; W240-P329 HydrophobicContact CZ3-CG 4.4Å; V277-P329 HydrophobicContact CG1-CB 4.31Å; V277-P329 HydrophobicContact CG1-CG 4.36Å; I278-P329 HydrophobicContact CG1-CB 3.98Å; A281-P329 HydrophobicContact CB-CB 4.01Å; A281-P329 HydrophobicContact CB-CG 3.71Å; I326-P329 VanDerWaalsContact O-CD 3.31Å; I326-P329 WeakPolarHBondContact O-CD 3.04Å; L327-P329 VanDerWaalsContact C-CD 3.46Å; L327-P329 VanDerWaalsContact C-N 3.35Å; P329-C333 WeakPolarHBondContact O-CB 3.23Å; P329-C333 PolarHBondContact O-N 2.84Å; P329-C333 VanDerWaalsContact O-N 3.12Å; P329-C333 PolarHBondContact O-SG 3.28Å
330L97.9Very high95.7Very high1 Ų135.1 Ų35.11%0.00518%0.183CC..Hα-helixtrans-70.2-52.5-178.9179.663.8000111.9I278 V282 L327 A328 C334 I336 V384 T387 V388I278-L330 HydrophobicContact CG2-CB 4.19Å; I278-L330 HydrophobicContact CG2-CD1 3.8Å; V282-L330 HydrophobicContact CG2-CD2 4.15Å; L327-L330 HydrophobicContact CD2-CD2 4.16Å; L327-L330 WeakPolarHBondContact O-CA 3.3Å; L327-L330 WeakPolarHBondContact O-CB 3.39Å; L327-L330 PolarHBondContact O-N 2.85Å; A328-L330 VanDerWaalsContact C-N 3.27Å; A328-L330 PolarHBondContact O-N 2.83Å; L330-C334 VanDerWaalsContact O-CA 3.27Å; L330-C334 WeakPolarHBondContact O-CA 3.35Å; L330-C334 PolarHBondContact O-N 3.42Å; L330-I336 HydrophobicContact CD1-CB 4.1Å; L330-I336 HydrophobicContact CD1-CD1 4.41Å; L330-V384 HydrophobicContact CD2-CG1 4.13Å; L330-T387 HydrophobicContact CD2-CG2 3.84Å; L330-T387 HydrophobicContact CG-CG2 3.99Å; L330-V388 HydrophobicContact CD1-CG2 4.19Å; L330-V388 HydrophobicContact CD2-CG2 3.98Å
331Y96.8Very high95.6Very high75 Ų7531.6 Ų31.629%0.29415%0.154SC..Hα-helixtrans-77.4-21.9-174.569.2-112.6000113.7L327 A328L327-Y331 HydrophobicContact CB-CD1 4.09Å; L327-Y331 WeakPolarHBondContact O-CD1 3.31Å; L327-Y331 PolarHBondContact O-N 2.82Å; A328-Y331 VanDerWaalsContact CA-CZ 3.4Å; A328-Y331 HydrophobicContact CB-CE1 3.93Å; A328-Y331 HydrophobicContact CB-CE2 4.41Å; A328-Y331 WeakPolarHBondContact CB-OH 3.34Å; A328-Y331 VanDerWaalsContact N-CE1 3.3Å
332Q97.2Very high95.3Very high27 Ų2730.9 Ų30.913%0.12615%0.15CC..Hα-helixtrans-84.9-40.8175-66.7-178.7-17.800112W252 C259 A328W252-Q332 PolarHBondContact O-NE2 3.12Å; C259-Q332 HydrophobicContact CB-CB 3.94Å; A328-Q332 WeakPolarHBondContact O-CB 3.33Å; A328-Q332 VanDerWaalsContact O-CG 3.27Å; A328-Q332 WeakPolarHBondContact O-CG 3.33Å; A328-Q332 PolarHBondContact O-N 3.48Å
333C97Very high94.8Very high2 Ų231.9 Ų31.91%0.01415%0.151CC..Hα-helixtrans-83-22.9-179.6-57.50000113C259 I278 P329 M335C259-C333 HydrophobicContact CB-CB 4.04Å; C259-C333 WeakPolarHBondContact CB-SG 3.2Å; C259-C333 WeakPolarHBondContact SG-CA 3.14Å; C259-C333 WeakPolarHBondContact SG-CB 3.42Å; C259-C333 CovalentContact SG-SG 2.02Å; C259-C333 PolarHBondContact SG-SG 3.12Å; I278-C333 HydrophobicContact CD1-CB 3.91Å; P329-C333 WeakPolarHBondContact O-CB 3.23Å; P329-C333 PolarHBondContact O-N 2.84Å; P329-C333 VanDerWaalsContact O-N 3.12Å; P329-C333 PolarHBondContact O-SG 3.28Å; C333-M335 HydrophobicContact CB-CG 3.83Å; C333-M335 HydrophobicContact CB-SD 4.05Å; C333-M335 PolarHBondContact O-N 3.32Å
334C96.7Very high94.5Very high10 Ų1029.7 Ų29.77%0.06814%0.141CC..  trans46.944.5-176.6-85.70000113.9L330 C391 T400L330-C334 VanDerWaalsContact O-CA 3.27Å; L330-C334 WeakPolarHBondContact O-CA 3.35Å; L330-C334 PolarHBondContact O-N 3.42Å; C334-C391 WeakPolarHBondContact CA-SG 3.37Å; C334-C391 HydrophobicContact CB-CB 3.52Å; C334-C391 WeakPolarHBondContact CB-SG 3.35Å; C334-C391 VanDerWaalsContact SG-CA 3.59Å; C334-C391 WeakPolarHBondContact SG-CB 3.31Å; C334-C391 CovalentContact SG-SG 2.06Å; C334-C391 PolarHBondContact SG-SG 2.97Å; C334-T400 VanDerWaalsContact O-CA 3.31Å; C334-T400 WeakPolarHBondContact O-CA 3.34Å
335M95.2Very high94.2Very high30 Ų3024.1 Ų24.115%0.14813%0.125CC..  trans-138144178.363.3-167.7-71.500109.9L274 L275 I278 C333 T400 I402L274-M335 HydrophobicContact CD2-CE 4.22Å; L274-M335 HydrophobicContact CD2-SD 3.71Å; L274-M335 HydrophobicContact CG-SD 4.24Å; L275-M335 HydrophobicContact CD2-CE 3.55Å; L275-M335 HydrophobicContact CD2-CG 4.32Å; L275-M335 HydrophobicContact CG-CE 4.01Å; I278-M335 HydrophobicContact CD1-CG 3.27Å; I278-M335 WeakPolarHBondContact CD1-O 3.47Å; I278-M335 HydrophobicContact CD1-SD 4.05Å; I278-M335 WeakPolarHBondContact CG2-O 3.38Å; C333-M335 HydrophobicContact CB-CG 3.83Å; C333-M335 HydrophobicContact CB-SD 4.05Å; C333-M335 PolarHBondContact O-N 3.32Å; M335-T400 CarbonylContact C-O 3.6Å; M335-T400 VanDerWaalsContact CA-O 3.3Å; M335-T400 WeakPolarHBondContact CA-O 3.27Å; M335-I402 HydrophobicContact CB-CG1 4.02Å; M335-I402 HydrophobicContact CE-CG1 4.27Å
336I95.6Very high93.8Very high0 Ų026.5 Ų26.50%013%0.132CC..EExtended strand (participates in β ladder)trans-151.7147.9176.3-171169.7000109.2V282 L330 T340 W341 L344 V388 T400 L401 I402V282-I336 HydrophobicContact CG2-CD1 4.4Å; L330-I336 HydrophobicContact CD1-CB 4.1Å; L330-I336 HydrophobicContact CD1-CD1 4.41Å; I336-T340 HydrophobicContact CD1-CG2 4.02Å; I336-T340 HydrophobicContact CG1-CG2 4.25Å; I336-W341 HydrophobicContact CG2-CB 4.38Å; I336-L344 HydrophobicContact CD1-CD1 3.98Å; I336-V388 HydrophobicContact CD1-CG2 4Å; I336-V388 HydrophobicContact CG2-CG1 3.92Å; I336-V388 HydrophobicContact CG2-CG2 4.29Å; I336-T400 HydrophobicContact CG2-CG2 4.5Å; I336-T400 PolarHBondContact N-O 3.11Å; I336-L401 HydrophobicContact CG2-CD2 3.73Å; I336-I402 PolarHBondContact O-N 3.33Å
337R93.3Very high93.3Very high17 Ų1725.7 Ų25.76%0.06413%0.128CC..EExtended strand (participates in β ladder)trans-66.9136.4177.3-163.4178.9-75.4101.4-9.1110.4D276 D279 S339 T340 W341 I402 D404D276-R337 IonicContact OD1-CZ 3.06Å; D276-R337 IonicContact OD1-NH1 2.84Å; D276-R337 IonicContact OD1-NH2 2.79Å; D276-R337 PolarHBondContact OD1-NH2 3.47Å; D276-R337 VanDerWaalsContact OD1-NH2 3.12Å; D279-R337 IonicContact OD1-NH1 3.52Å; D279-R337 IonicContact OD2-CZ 2.88Å; D279-R337 IonicContact OD2-NH1 3.45Å; D279-R337 PolarHBondContact OD2-NH1 3.21Å; R337-S339 WeakPolarHBondContact CD-OG 3.27Å; R337-S339 VanDerWaalsContact CG-OG 3.31Å; R337-S339 WeakPolarHBondContact CG-OG 3.19Å; R337-S339 PolarHBondContact O-N 3.39Å; R337-T340 WeakPolarHBondContact O-CB 3.46Å; R337-T340 PolarHBondContact O-N 2.85Å; R337-W341 PolarHBondContact O-N 3.29Å; R337-I402 WeakPolarHBondContact CA-O 3.14Å; R337-D404 HydrophobicContact CG-CB 3.89Å; R337-D404 IonicContact CZ-OD2 3.69Å; R337-D404 VanDerWaalsContact CZ-OD2 3.23Å; R337-D404 VanDerWaalsContact NE-CB 3.26Å; R337-D404 IonicContact NE-OD2 3.67Å; R337-D404 PolarHBondContact NE-OD2 3.27Å; R337-D404 IonicContact NH2-OD2 2.79Å; R337-D404 PolarHBondContact NH2-OD2 3.34Å
338V91.8Very high92.9Very high39 Ų3928.8 Ų28.824%0.23614%0.141CC..Hα-helixtrans-53.6-41.6176.7171.70000111.4T340 W341 N342 L401 I402 E403V338-T340 PolarHBondContact O-N 2.96Å; V338-W341 PolarHBondContact O-N 2.81Å; V338-N342 WeakPolarHBondContact O-CB 3.42Å; V338-N342 VanDerWaalsContact O-CG 3.24Å; V338-N342 PolarHBondContact O-N 2.94Å; V338-N342 PolarHBondContact O-ND2 3.37Å; V338-L401 HydrophobicContact CG2-CB 3.88Å; V338-I402 PolarHBondContact N-O 3.1Å; V338-E403 HydrophobicContact CG2-CG 4.11Å
339S87.5Confident92.5Very high50 Ų5032.7 Ų32.735%0.3518%0.181SC..Hα-helixtrans-59.7-44.9177.260.20000111.9R337 R343R337-S339 WeakPolarHBondContact CD-OG 3.27Å; R337-S339 VanDerWaalsContact CG-OG 3.31Å; R337-S339 WeakPolarHBondContact CG-OG 3.19Å; R337-S339 PolarHBondContact O-N 3.39Å; S339-R343 WeakPolarHBondContact O-CB 3.31Å; S339-R343 VanDerWaalsContact O-CD 3.3Å; S339-R343 WeakPolarHBondContact O-CD 3.36Å; S339-R343 WeakPolarHBondContact O-CG 3.2Å; S339-R343 PolarHBondContact O-N 3.46Å
340T90.9Very high92.1Very high3 Ų333.9 Ų33.92%0.01819%0.194CC..Hα-helixtrans-64.9-46.3178.9-52.30000110.3F161 D279 I336 R337 V338 N342 R343 L344F161-T340 HydrophobicContact CE1-CG2 3.91Å; F161-T340 HydrophobicContact CZ-CG2 3.85Å; D279-T340 WeakPolarHBondContact OD1-CB 3.46Å; D279-T340 WeakPolarHBondContact OD1-CG2 3.29Å; D279-T340 PolarHBondContact OD1-OG1 2.91Å; I336-T340 HydrophobicContact CD1-CG2 4.02Å; I336-T340 HydrophobicContact CG1-CG2 4.25Å; R337-T340 WeakPolarHBondContact O-CB 3.46Å; R337-T340 PolarHBondContact O-N 2.85Å; V338-T340 PolarHBondContact O-N 2.96Å; T340-N342 PolarHBondContact O-N 3.34Å; T340-R343 PolarHBondContact O-N 3.38Å; T340-L344 HydrophobicContact CG2-CD1 3.97Å; T340-L344 HydrophobicContact CG2-CG 4.3Å; T340-L344 WeakPolarHBondContact O-CB 3.17Å; T340-L344 VanDerWaalsContact O-CG 3.24Å; T340-L344 WeakPolarHBondContact O-CG 3.09Å; T340-L344 PolarHBondContact O-N 2.81Å
341W93.2Very high91.8Very high31 Ų3135.7 Ų35.712%0.11721%0.205CC..Hα-helixtrans-58-46.1177.1171-111.2000113.3I336 R337 V338 L344 S345 I385 V388 K389 M392 L401I336-W341 HydrophobicContact CG2-CB 4.38Å; R337-W341 PolarHBondContact O-N 3.29Å; V338-W341 PolarHBondContact O-N 2.81Å; W341-L344 PolarHBondContact O-N 2.84Å; W341-S345 WeakPolarHBondContact O-CB 3.1Å; W341-S345 PolarHBondContact O-N 2.9Å; W341-S345 PolarHBondContact O-OG 3.36Å; W341-S345 VanDerWaalsContact O-OG 3.07Å; W341-I385 HydrophobicContact CH2-CG2 4.06Å; W341-I385 HydrophobicContact CZ3-CB 4.46Å; W341-I385 HydrophobicContact CZ3-CG1 4.38Å; W341-I385 HydrophobicContact CZ3-CG2 4.24Å; W341-V388 HydrophobicContact CD2-CG1 4.19Å; W341-V388 HydrophobicContact CE3-CB 3.9Å; W341-V388 HydrophobicContact CE3-CG1 3.56Å; W341-V388 HydrophobicContact CE3-CG2 4.07Å; W341-V388 HydrophobicContact CH2-CB 4.31Å; W341-V388 HydrophobicContact CH2-CG1 4.17Å; W341-V388 HydrophobicContact CZ3-CB 3.53Å; W341-V388 HydrophobicContact CZ3-CG1 3.56Å; W341-V388 HydrophobicContact CZ3-CG2 4.03Å; W341-K389 HydrophobicContact CH2-CG 4.18Å; W341-M392 HydrophobicContact CZ2-SD 4.33Å; W341-L401 HydrophobicContact CB-CD2 3.89Å; W341-L401 HydrophobicContact CD2-CD2 4.3Å; W341-L401 HydrophobicContact CG-CD2 3.74Å
342N89.4Confident91.5Very high74 Ų7432.1 Ų32.140%0.39619%0.191SC..Hα-helixtrans-62.6-46.2178.8-70.4-16.2000110.5V338 T340 S345 F346V338-N342 WeakPolarHBondContact O-CB 3.42Å; V338-N342 VanDerWaalsContact O-CG 3.24Å; V338-N342 PolarHBondContact O-N 2.94Å; V338-N342 PolarHBondContact O-ND2 3.37Å; T340-N342 PolarHBondContact O-N 3.34Å; N342-S345 WeakPolarHBondContact O-CB 2.99Å; N342-S345 PolarHBondContact O-N 2.85Å; N342-S345 VanDerWaalsContact O-N 3.15Å; N342-F346 HydrophobicContact CB-CE2 4.4Å; N342-F346 WeakPolarHBondContact O-CD2 3.33Å; N342-F346 PolarHBondContact O-N 3.26Å; N342-F346 VanDerWaalsContact O-N 3.15Å
343R86.9Confident91.4Very high65 Ų6531.4 Ų31.425%0.24519%0.189CC..Hα-helixtrans-59.5-50.1177.6-72.9167.6178.3-77.53.7112R157 I158 L159 S339 T340 S345 F346 L347R157-R343 PolarHBondContact O-NH1 3.29Å; I158-R343 HydrophobicContact CG2-CB 3.68Å; I158-R343 HydrophobicContact CG2-CG 4.18Å; I158-R343 WeakPolarHBondContact CG2-O 3.41Å; I158-R343 WeakPolarHBondContact O-CB 3.49Å; I158-R343 WeakPolarHBondContact O-CD 3.45Å; I158-R343 WeakPolarHBondContact O-CG 3.39Å; I158-R343 PolarHBondContact O-NH1 2.89Å; L159-R343 WeakPolarHBondContact O-CD 3.32Å; S339-R343 WeakPolarHBondContact O-CB 3.31Å; S339-R343 VanDerWaalsContact O-CD 3.3Å; S339-R343 WeakPolarHBondContact O-CD 3.36Å; S339-R343 WeakPolarHBondContact O-CG 3.2Å; S339-R343 PolarHBondContact O-N 3.46Å; T340-R343 PolarHBondContact O-N 3.38Å; R343-S345 PolarHBondContact O-N 3.42Å; R343-F346 PolarHBondContact O-N 2.84Å; R343-F346 VanDerWaalsContact O-N 3.13Å; R343-L347 PolarHBondContact O-N 2.89Å
344L91.1Very high91.1Very high1 Ų134.5 Ų34.51%0.00521%0.21CC..Hα-helixtrans-58.5-36.1175.4-67.5169.6000112.2L159 V282 L286 I336 T340 W341 F346 L347 L381 V384L159-L344 HydrophobicContact CD2-CD2 3.73Å; V282-L344 HydrophobicContact CG1-CD1 4.05Å; V282-L344 HydrophobicContact CG1-CD2 4.04Å; L286-L344 HydrophobicContact CD1-CD2 4.46Å; I336-L344 HydrophobicContact CD1-CD1 3.98Å; T340-L344 HydrophobicContact CG2-CD1 3.97Å; T340-L344 HydrophobicContact CG2-CG 4.3Å; T340-L344 WeakPolarHBondContact O-CB 3.17Å; T340-L344 VanDerWaalsContact O-CG 3.24Å; T340-L344 WeakPolarHBondContact O-CG 3.09Å; T340-L344 PolarHBondContact O-N 2.81Å; W341-L344 PolarHBondContact O-N 2.84Å; L344-F346 VanDerWaalsContact C-N 3.34Å; L344-F346 PolarHBondContact O-N 3.39Å; L344-L347 PolarHBondContact O-N 3.39Å; L344-L381 HydrophobicContact CB-CD1 4.03Å; L344-L381 HydrophobicContact CD2-CD1 3.63Å; L344-L381 HydrophobicContact CG-CD1 4.4Å; L344-V384 HydrophobicContact CD1-CG1 3.88Å
345S90.1Very high90.8Very high33 Ų3334.2 Ų34.223%0.23121%0.209CC..Hα-helixtrans-67.4-32.4178.4-71.80000113.6W341 N342 R343 L347 K348W341-S345 WeakPolarHBondContact O-CB 3.1Å; W341-S345 PolarHBondContact O-N 2.9Å; W341-S345 PolarHBondContact O-OG 3.36Å; W341-S345 VanDerWaalsContact O-OG 3.07Å; N342-S345 WeakPolarHBondContact O-CB 2.99Å; N342-S345 PolarHBondContact O-N 2.85Å; N342-S345 VanDerWaalsContact O-N 3.15Å; R343-S345 PolarHBondContact O-N 3.42Å; S345-L347 VanDerWaalsContact C-N 3.27Å; S345-L347 PolarHBondContact O-N 2.96Å; S345-K348 WeakPolarHBondContact O-CD 3.31Å; S345-K348 WeakPolarHBondContact O-CG 3.35Å; S345-K348 PolarHBondContact OG-NZ 2.97Å
346F86.9Confident90.6Very high76 Ų7632.8 Ų32.833%0.33320%0.202SC..Hα-helixtrans-72.3-19.7174.9-69.5-59.8000113.8D37 I158 N342 R343 L344D37-F346 HydrophobicContact CB-CE1 3.74Å; D37-F346 HydrophobicContact CB-CZ 3.71Å; I158-F346 HydrophobicContact CD1-CB 4.32Å; I158-F346 HydrophobicContact CG2-CB 4.4Å; N342-F346 HydrophobicContact CB-CE2 4.4Å; N342-F346 WeakPolarHBondContact O-CD2 3.33Å; N342-F346 PolarHBondContact O-N 3.26Å; N342-F346 VanDerWaalsContact O-N 3.15Å; R343-F346 PolarHBondContact O-N 2.84Å; R343-F346 VanDerWaalsContact O-N 3.13Å; L344-F346 VanDerWaalsContact C-N 3.34Å; L344-F346 PolarHBondContact O-N 3.39Å
347L88.4Confident90.5Very high0 Ų037.4 Ų37.40%022%0.219CC..THydrogen-bonded Turntrans-88.80.2-177.2-73.5168.6000114.2L156 I158 L159 R343 L344 S345 V351 L352 L381L156-L347 HydrophobicContact CD2-CD1 4.44Å; L156-L347 HydrophobicContact CD2-CD2 3.72Å; I158-L347 HydrophobicContact CB-CD1 3.97Å; I158-L347 HydrophobicContact CB-CD2 3.91Å; I158-L347 HydrophobicContact CB-CG 3.93Å; I158-L347 HydrophobicContact CD1-CD2 3.3Å; I158-L347 HydrophobicContact CD1-CG 3.79Å; I158-L347 HydrophobicContact CG1-CD2 4.2Å; I158-L347 HydrophobicContact CG1-CG 4.47Å; I158-L347 HydrophobicContact CG2-CD1 3.56Å; I158-L347 HydrophobicContact CG2-CD2 4.09Å; I158-L347 HydrophobicContact CG2-CG 3.53Å; L159-L347 HydrophobicContact CD2-CD1 4.31Å; L159-L347 HydrophobicContact CG-CD1 4.01Å; R343-L347 PolarHBondContact O-N 2.89Å; L344-L347 PolarHBondContact O-N 3.39Å; S345-L347 VanDerWaalsContact C-N 3.27Å; S345-L347 PolarHBondContact O-N 2.96Å; L347-V351 HydrophobicContact CD2-CG1 4.18Å; L347-L352 HydrophobicContact CB-CB 4.17Å; L347-L352 HydrophobicContact CD1-CD1 4.19Å; L347-L352 HydrophobicContact CD2-CB 4.33Å; L347-L352 HydrophobicContact CD2-CD1 4.17Å; L347-L352 PolarHBondContact O-N 3.17Å; L347-L352 VanDerWaalsContact O-N 3.15Å; L347-L381 VanDerWaalsContact C-CD2 3.42Å; L347-L381 HydrophobicContact CB-CD2 3.58Å; L347-L381 WeakPolarHBondContact O-CD2 3.27Å
348K90.3Very high90.3Very high68 Ų6840.4 Ų40.430%0.29623%0.234SC..THydrogen-bonded Turntrans-64.6161.7-178.4-71.9171.1179.5153.50112.5S345 V351 I385S345-K348 WeakPolarHBondContact O-CD 3.31Å; S345-K348 WeakPolarHBondContact O-CG 3.35Å; S345-K348 PolarHBondContact OG-NZ 2.97Å; K348-V351 VanDerWaalsContact O-CG2 3.3Å; K348-V351 WeakPolarHBondContact O-CG2 3.47Å; K348-I385 HydrophobicContact CD-CD1 3.84Å; K348-I385 HydrophobicContact CG-CD1 3.43Å; K348-I385 VanDerWaalsContact CG-CD1 3.43Å
349G89.2Confident90.2Very high82 Ų8238.8 Ų38.885%0.84523%0.225SC*.THydrogen-bonded Turntrans72.530.7167.900000114.9
350G89.3Confident90.5Very high27 Ų2736.6 Ų36.628%0.27821%0.209SC..THydrogen-bonded Turntrans89.7-0.1178.900000114.7S353 S354 D378G350-S353 PolarHBondContact O-OG 2.89Å; G350-S354 WeakPolarHBondContact O-CB 3.07Å; G350-S354 PolarHBondContact O-N 3.19Å; G350-D378 WeakPolarHBondContact CA-OD2 3.43Å
351V90.2Very high90.5Very high40 Ų4038.1 Ų38.124%0.24222%0.222CC..Hα-helixtrans-66.5-39178.4174.90000110.8F41 L347 K348 S354 A355F41-V351 HydrophobicContact CE2-CG1 3.89Å; F41-V351 HydrophobicContact CZ-CG1 4.17Å; L347-V351 HydrophobicContact CD2-CG1 4.18Å; K348-V351 VanDerWaalsContact O-CG2 3.3Å; K348-V351 WeakPolarHBondContact O-CG2 3.47Å; V351-S354 PolarHBondContact O-N 3.25Å; V351-A355 VanDerWaalsContact O-CB 3.23Å; V351-A355 WeakPolarHBondContact O-CB 3.35Å; V351-A355 PolarHBondContact O-N 2.02Å
352L92.1Very high90.4Very high0 Ų037.8 Ų37.80%022%0.221CC..Hα-helixtrans-59.7-53.5179.6179.254.4000112.3L153 L156 L286 L347 S354 A355 M356 L377 D378 L381L153-L352 HydrophobicContact CD1-CD1 3.74Å; L156-L352 HydrophobicContact CD2-CD1 4.49Å; L286-L352 HydrophobicContact CD2-CD2 4.3Å; L347-L352 HydrophobicContact CB-CB 4.17Å; L347-L352 HydrophobicContact CD1-CD1 4.19Å; L347-L352 HydrophobicContact CD2-CB 4.33Å; L347-L352 HydrophobicContact CD2-CD1 4.17Å; L347-L352 PolarHBondContact O-N 3.17Å; L347-L352 VanDerWaalsContact O-N 3.15Å; L352-S354 VanDerWaalsContact C-N 3.31Å; L352-S354 PolarHBondContact O-N 2.96Å; L352-A355 PolarHBondContact O-N 3.12Å; L352-M356 VanDerWaalsContact O-CB 3.28Å; L352-M356 WeakPolarHBondContact O-CB 3.31Å; L352-M356 PolarHBondContact O-N 3.25Å; L352-L377 HydrophobicContact CD2-CB 3.9Å; L352-L377 HydrophobicContact CG-CB 4.13Å; L352-D378 WeakPolarHBondContact CB-OD1 3.47Å; L352-L381 HydrophobicContact CB-CD2 4.1Å; L352-L381 HydrophobicContact CD2-CB 4.05Å; L352-L381 HydrophobicContact CD2-CD2 4.06Å
353S93.6Very high90.7Very high12 Ų1234.5 Ų34.58%0.08420%0.204CC..Hα-helixtrans-62.9-37.9179.264.90000112.8G350 M356 R357 L374 D378G350-S353 PolarHBondContact O-OG 2.89Å; S353-M356 PolarHBondContact O-N 3.25Å; S353-R357 WeakPolarHBondContact O-CB 3.37Å; S353-R357 PolarHBondContact O-N 3.49Å; S353-L374 VanDerWaalsContact CB-O 3.24Å; S353-L374 WeakPolarHBondContact CB-O 3.4Å; S353-D378 WeakPolarHBondContact CB-OD2 3.42Å; S353-D378 PolarHBondContact N-OD1 3.45Å; S353-D378 PolarHBondContact OG-OD2 2.74Å
354S91.7Very high91.1Very high66 Ų6634.4 Ų34.446%0.46221%0.212SC..Hα-helixtrans-63.8-49.4176.6-169.80000112.2G350 V351 L352 M356 R357 Q358G350-S354 WeakPolarHBondContact O-CB 3.07Å; G350-S354 PolarHBondContact O-N 3.19Å; V351-S354 PolarHBondContact O-N 3.25Å; L352-S354 VanDerWaalsContact C-N 3.31Å; L352-S354 PolarHBondContact O-N 2.96Å; S354-M356 VanDerWaalsContact C-N 3.3Å; S354-M356 PolarHBondContact O-N 3.45Å; S354-R357 PolarHBondContact O-N 3.34Å; S354-Q358 PolarHBondContact O-N 3.37Å
355A89.9Confident91.4Very high4 Ų434.4 Ų34.43%0.03321%0.212CC..Hα-helixtrans-62.1-40.7177.400000111.3L48 L156 V351 L352 Q358 A359L48-A355 HydrophobicContact CD1-CB 3.61Å; L48-A355 HydrophobicContact CD2-CB 4.41Å; L156-A355 HydrophobicContact CD1-CB 3.86Å; L156-A355 HydrophobicContact CD2-CB 4.12Å; L156-A355 HydrophobicContact CG-CB 4.33Å; V351-A355 VanDerWaalsContact O-CB 3.23Å; V351-A355 WeakPolarHBondContact O-CB 3.35Å; V351-A355 PolarHBondContact O-N 2.02Å; L352-A355 PolarHBondContact O-N 3.12Å; A355-Q358 PolarHBondContact O-N 3.45Å; A355-A359 WeakPolarHBondContact O-CB 3.36Å; A355-A359 PolarHBondContact O-N 3.31Å
356M92.3Very high91.6Very high0 Ų036.7 Ų36.70%022%0.221CC..Hα-helixtrans-62.6-44.6176.3-164.272.1-142.700111.4A149 H152 L153 L156 L352 S353 S354 Q358 A359 L360 L369 L374 L377A149-M356 HydrophobicContact CB-CE 4.36Å; A149-M356 WeakPolarHBondContact O-CE 3.49Å; H152-M356 HydrophobicContact CB-CE 3.35Å; L153-M356 HydrophobicContact CB-CE 4.29Å; L153-M356 HydrophobicContact CB-SD 3.95Å; L153-M356 HydrophobicContact CD1-SD 3.98Å; L156-M356 HydrophobicContact CD1-CB 4.44Å; L156-M356 HydrophobicContact CD1-SD 4.07Å; L352-M356 VanDerWaalsContact O-CB 3.28Å; L352-M356 WeakPolarHBondContact O-CB 3.31Å; L352-M356 PolarHBondContact O-N 3.25Å; S353-M356 PolarHBondContact O-N 3.25Å; S354-M356 VanDerWaalsContact C-N 3.3Å; S354-M356 PolarHBondContact O-N 3.45Å; M356-Q358 VanDerWaalsContact C-N 3.31Å; M356-Q358 PolarHBondContact O-N 2.89Å; M356-A359 PolarHBondContact O-N 3.18Å; M356-L360 HydrophobicContact CE-CD1 3.68Å; M356-L360 HydrophobicContact CE-CD2 3.55Å; M356-L360 HydrophobicContact CE-CG 3.56Å; M356-L360 HydrophobicContact CG-CD1 3.83Å; M356-L360 HydrophobicContact CG-CG 4.36Å; M356-L360 WeakPolarHBondContact O-CB 3.49Å; M356-L360 WeakPolarHBondContact O-CG 3.46Å; M356-L360 PolarHBondContact O-N 2.96Å; M356-L369 HydrophobicContact CG-CD1 4.47Å; M356-L374 HydrophobicContact CB-CD2 3.87Å; M356-L374 HydrophobicContact CG-CD2 3.84Å; M356-L377 HydrophobicContact CB-CD1 4.28Å; M356-L377 HydrophobicContact CG-CD1 3.94Å
357R92.2Very high92.1Very high97 Ų9737.2 Ų37.237%0.36623%0.232SC..Hα-helixtrans-59.7-41.9176.9-168.9-179.2-65.195.9-1.2111.7S353 S354 A361 E371 L374S353-R357 WeakPolarHBondContact O-CB 3.37Å; S353-R357 PolarHBondContact O-N 3.49Å; S354-R357 PolarHBondContact O-N 3.34Å; R357-A361 PolarHBondContact O-N 3.23Å; R357-E371 IonicContact CZ-OE1 3.89Å; R357-E371 IonicContact CZ-OE2 3.29Å; R357-E371 IonicContact NE-OE1 3.71Å; R357-E371 PolarHBondContact NE-OE1 3.43Å; R357-E371 IonicContact NE-OE2 2.96Å; R357-E371 IonicContact NH2-OE1 3.47Å; R357-E371 PolarHBondContact NH2-OE1 3.17Å; R357-E371 IonicContact NH2-OE2 2.73Å; R357-E371 PolarHBondContact NH2-OE2 3.27Å; R357-L374 HydrophobicContact CB-CD1 4.25Å; R357-L374 HydrophobicContact CG-CD1 4.37Å
358Q90Very high92.5Very high81 Ų8137.3 Ų37.338%0.37923%0.233SC..Hα-helixtrans-67.3-44.8177.4-172.1173.732.600112.2L48 S49 S354 A355 M356 L360 A361L48-Q358 HydrophobicContact CB-CG 4.35Å; S49-Q358 PolarHBondContact OG-NE2 3.07Å; S354-Q358 PolarHBondContact O-N 3.37Å; A355-Q358 PolarHBondContact O-N 3.45Å; M356-Q358 VanDerWaalsContact C-N 3.31Å; M356-Q358 PolarHBondContact O-N 2.89Å; Q358-L360 PolarHBondContact O-N 2.99Å; Q358-A361 WeakPolarHBondContact O-CB 3.14Å; Q358-A361 PolarHBondContact O-N 2.92Å
359A89.4Confident92.8Very high5 Ų534.5 Ų34.54%0.04122%0.221CC..Hα-helixtrans-63-41.8179.400000112.2H152 A355 M356 A361H152-A359 HydrophobicContact CB-CB 4.45Å; H152-A359 PolarHBondContact CE1-O 3.49Å; H152-A359 PolarHBondContact ND1-O 3.39Å; A355-A359 WeakPolarHBondContact O-CB 3.36Å; A355-A359 PolarHBondContact O-N 3.31Å; M356-A359 PolarHBondContact O-N 3.18Å; A359-A361 VanDerWaalsContact C-N 3.3Å; A359-A361 PolarHBondContact O-N 3.39Å
360L92.8Very high93.2Very high4 Ų431.2 Ų31.22%0.02119%0.186CC..Hα-helixtrans-72.3-21.1180-66.2171.2000113.7V148 A149 H152 M356 Q358 F362 D363 V368 L369V148-L360 HydrophobicContact CG1-CD2 4.41Å; A149-L360 HydrophobicContact CB-CD2 4.48Å; H152-L360 HydrophobicContact CB-CD2 3.78Å; M356-L360 HydrophobicContact CE-CD1 3.68Å; M356-L360 HydrophobicContact CE-CD2 3.55Å; M356-L360 HydrophobicContact CE-CG 3.56Å; M356-L360 HydrophobicContact CG-CD1 3.83Å; M356-L360 HydrophobicContact CG-CG 4.36Å; M356-L360 WeakPolarHBondContact O-CB 3.49Å; M356-L360 WeakPolarHBondContact O-CG 3.46Å; M356-L360 PolarHBondContact O-N 2.96Å; Q358-L360 PolarHBondContact O-N 2.99Å; L360-F362 PolarHBondContact O-N 3.14Å; L360-F362 VanDerWaalsContact O-N 3.15Å; L360-D363 WeakPolarHBondContact O-CB 3.49Å; L360-D363 PolarHBondContact O-N 3.15Å; L360-V368 HydrophobicContact CB-CB 4.36Å; L360-V368 HydrophobicContact CB-CG2 4.22Å; L360-V368 HydrophobicContact CD1-CB 4.18Å; L360-V368 HydrophobicContact CD2-CB 3.89Å; L360-V368 HydrophobicContact CD2-CG1 4.02Å; L360-V368 HydrophobicContact CD2-CG2 3.99Å; L360-V368 HydrophobicContact CG-CB 4.35Å; L360-L369 HydrophobicContact CD1-CB 4.25Å; L360-L369 HydrophobicContact CD1-CD1 3.96Å; L360-L369 HydrophobicContact CD1-CG 3.95Å
361A92.5Very high93.5Very high34 Ų3435 Ų3528%0.28120%0.196SC..THydrogen-bonded Turntrans-67.5-12.8-179.200000113.8R52 R357 Q358 A359R52-A361 PolarHBondContact NH2-O 2.96Å; R357-A361 PolarHBondContact O-N 3.23Å; Q358-A361 WeakPolarHBondContact O-CB 3.14Å; Q358-A361 PolarHBondContact O-N 2.92Å; A359-A361 VanDerWaalsContact C-N 3.3Å; A359-A361 PolarHBondContact O-N 3.39Å
362F90.3Very high93.9Very high25 Ų2536.5 Ų36.511%0.1121%0.207CC..THydrogen-bonded Turntrans-75.4-31.7170.8175.6-99000112.4L50 P51 R52 A85 L88 L360L50-F362 HydrophobicContact CB-CB 4.29Å; L50-F362 HydrophobicContact CB-CD1 4.31Å; L50-F362 HydrophobicContact CB-CD2 3.46Å; L50-F362 VanDerWaalsContact CB-CD2 3.46Å; L50-F362 HydrophobicContact CB-CE2 3.79Å; L50-F362 HydrophobicContact CB-CG 3.75Å; L50-F362 HydrophobicContact CB-CZ 4.35Å; L50-F362 HydrophobicContact CD1-CD1 3.9Å; L50-F362 HydrophobicContact CD1-CE1 4.11Å; L50-F362 HydrophobicContact CD1-CG 4.13Å; L50-F362 HydrophobicContact CG-CG 4.5Å; P51-F362 WeakPolarHBondContact O-CE2 3.36Å; R52-F362 HydrophobicContact CG-CD2 4.4Å; A85-F362 HydrophobicContact CB-CE2 4.32Å; A85-F362 HydrophobicContact CB-CZ 4.27Å; L88-F362 HydrophobicContact CB-CE1 3.78Å; L88-F362 HydrophobicContact CB-CZ 4.37Å; L88-F362 HydrophobicContact CD1-CD1 4.36Å; L88-F362 HydrophobicContact CD1-CE1 3.93Å; L360-F362 PolarHBondContact O-N 3.14Å; L360-F362 VanDerWaalsContact O-N 3.15Å
363D95.1Very high94.1Very high4 Ų436.9 Ų36.92%0.02121%0.209CC..SBendtrans-70.3138.1-169.9-167.6-73.8000112.2V148 G169 L360 I365 N366 V368V148-D363 HydrophobicContact CG1-CB 4.26Å; V148-D363 VanDerWaalsContact CG1-OD2 3.22Å; V148-D363 WeakPolarHBondContact CG1-OD2 3.44Å; G169-D363 WeakPolarHBondContact CA-OD1 3.48Å; G169-D363 PolarHBondContact N-OD1 2.76Å; G169-D363 PolarHBondContact N-OD2 2.94Å; L360-D363 WeakPolarHBondContact O-CB 3.49Å; L360-D363 PolarHBondContact O-N 3.15Å; D363-I365 PolarHBondContact O-N 3.46Å; D363-I365 VanDerWaalsContact OD1-CG1 3.29Å; D363-I365 WeakPolarHBondContact OD1-CG1 3.49Å; D363-I365 PolarHBondContact OD1-N 2.93Å; D363-N366 VanDerWaalsContact O-CB 3.23Å; D363-N366 WeakPolarHBondContact O-CB 3.43Å; D363-N366 PolarHBondContact O-N 3.09Å; D363-N366 VanDerWaalsContact O-N 3.12Å; D363-V368 HydrophobicContact CB-CG2 3.95Å
364P96.2Very high94.3Very high64 Ų6436.6 Ų36.642%0.41621%0.206SC..THydrogen-bonded Turntrans-57.8-26.5179.4-26.435.5000115.5V168 G169 N366V168-P364 HydrophobicContact CG2-CG 4.27Å; G169-P364 WeakPolarHBondContact O-CG 3.36Å; P364-N366 VanDerWaalsContact C-N 3.31Å
365I96.8Very high94.5Very high1 Ų136 Ų361%0.00521%0.205CC..THydrogen-bonded Turntrans-94.417.6-179.976.7177.9000112.8R129 V148 Y171 E220 D363 P367 V368R129-I365 PolarHBondContact NH2-O 3.35Å; R129-I365 VanDerWaalsContact NH2-O 3.12Å; V148-I365 HydrophobicContact CG2-CD1 4.27Å; Y171-I365 HydrophobicContact CD2-CG2 4.28Å; Y171-I365 HydrophobicContact CE2-CB 4.42Å; Y171-I365 HydrophobicContact CE2-CG2 3.8Å; E220-I365 HydrophobicContact CG-CB 4.28Å; E220-I365 HydrophobicContact CG-CG2 3.8Å; D363-I365 PolarHBondContact O-N 3.46Å; D363-I365 VanDerWaalsContact OD1-CG1 3.29Å; D363-I365 WeakPolarHBondContact OD1-CG1 3.49Å; D363-I365 PolarHBondContact OD1-N 2.93Å; I365-P367 CarbonylContact O-C 3.49Å; I365-P367 VanDerWaalsContact O-C 3.27Å; I365-P367 VanDerWaalsContact O-O 3.08Å; I365-V368 HydrophobicContact CG1-CG2 4.08Å
366N95.4Very high94.9Very high81 Ų8135.9 Ų35.943%0.43320%0.204SC..  trans-58.2130.3175.3178.774.3000111.2D363 P364D363-N366 VanDerWaalsContact O-CB 3.23Å; D363-N366 WeakPolarHBondContact O-CB 3.43Å; D363-N366 PolarHBondContact O-N 3.09Å; D363-N366 VanDerWaalsContact O-N 3.12Å; P364-N366 VanDerWaalsContact C-N 3.31Å
367P96.7Very high95.1Very high87 Ų8735.9 Ų35.957%0.56520%0.204SC*.  cis-74.91294.929.6-34.8000114.4R129 I365R129-P367 PolarHBondContact NE-O 2.99Å; R129-P367 PolarHBondContact NH2-O 2.9Å; I365-P367 CarbonylContact O-C 3.49Å; I365-P367 VanDerWaalsContact O-C 3.27Å; I365-P367 VanDerWaalsContact O-O 3.08Å
368V96.9Very high95.4Very high1 Ų132.5 Ų32.51%0.00619%0.193CC..  trans-82.8-43178.8-176.50000111.8R129 N145 V148 A149 L360 D363 I365R129-V368 VanDerWaalsContact CD-O 3.25Å; R129-V368 WeakPolarHBondContact CD-O 3.41Å; R129-V368 PolarHBondContact NE-O 3.14Å; R129-V368 VanDerWaalsContact NE-O 3.09Å; N145-V368 HydrophobicContact CB-CG1 3.96Å; N145-V368 WeakPolarHBondContact CB-O 3.25Å; N145-V368 PolarHBondContact ND2-O 3.47Å; N145-V368 VanDerWaalsContact O-CG1 3.29Å; N145-V368 WeakPolarHBondContact O-CG1 3.38Å; V148-V368 HydrophobicContact CB-CG1 3.9Å; V148-V368 HydrophobicContact CG1-CG1 3.79Å; V148-V368 HydrophobicContact CG1-CG2 4.04Å; A149-V368 HydrophobicContact CB-CG1 4.28Å; L360-V368 HydrophobicContact CB-CB 4.36Å; L360-V368 HydrophobicContact CB-CG2 4.22Å; L360-V368 HydrophobicContact CD1-CB 4.18Å; L360-V368 HydrophobicContact CD2-CB 3.89Å; L360-V368 HydrophobicContact CD2-CG1 4.02Å; L360-V368 HydrophobicContact CD2-CG2 3.99Å; L360-V368 HydrophobicContact CG-CB 4.35Å; D363-V368 HydrophobicContact CB-CG2 3.95Å; I365-V368 HydrophobicContact CG1-CG2 4.08Å
369L96.9Very high95.8Very high10 Ų1033.6 Ų33.65%0.05219%0.194CC..SBendtrans-116.1143177-67.6-178.4000110.4A149 F316 M356 L360 H373 L374A149-L369 HydrophobicContact CB-CD1 3.82Å; A149-L369 HydrophobicContact CB-CD2 3.75Å; A149-L369 HydrophobicContact CB-CG 3.78Å; F316-L369 HydrophobicContact CB-CD2 4.15Å; F316-L369 HydrophobicContact CD1-CD1 4.1Å; F316-L369 HydrophobicContact CD1-CD2 3.8Å; F316-L369 HydrophobicContact CD2-CD2 4.15Å; F316-L369 HydrophobicContact CE1-CD1 3.68Å; F316-L369 HydrophobicContact CE1-CD2 4.18Å; F316-L369 HydrophobicContact CG-CD2 3.77Å; F316-L369 HydrophobicContact CZ-CD1 3.99Å; M356-L369 HydrophobicContact CG-CD1 4.47Å; L360-L369 HydrophobicContact CD1-CB 4.25Å; L360-L369 HydrophobicContact CD1-CD1 3.96Å; L360-L369 HydrophobicContact CD1-CG 3.95Å; L369-H373 HydrophobicContact CB-CB 4.41Å; L369-H373 HydrophobicContact CD2-CB 4.5Å; L369-L374 HydrophobicContact CB-CD2 4.45Å; L369-L374 HydrophobicContact CB-CG 4.39Å; L369-L374 HydrophobicContact CD1-CD2 4.14Å
370A96.6Very high96.2Very high13 Ų1333.5 Ų33.511%0.10719%0.193CC..  trans-73.2151.6168.500000110.7P372 H373 L374A370-P372 VanDerWaalsContact C-CD 3.42Å; A370-P372 VanDerWaalsContact C-N 3.33Å; A370-H373 WeakPolarHBondContact O-CB 3.5Å; A370-H373 PolarHBondContact O-N 3.41Å; A370-L374 PolarHBondContact O-N 3.17Å
371E96.1Very high96.4Very high107 Ų10733.4 Ų33.450%0.519%0.192SC..Hα-helixtrans-53.2-38-178.8-74.7-63.6153.300114.6R357 H373 L374 A375R357-E371 IonicContact CZ-OE1 3.89Å; R357-E371 IonicContact CZ-OE2 3.29Å; R357-E371 IonicContact NE-OE1 3.71Å; R357-E371 PolarHBondContact NE-OE1 3.43Å; R357-E371 IonicContact NE-OE2 2.96Å; R357-E371 IonicContact NH2-OE1 3.47Å; R357-E371 PolarHBondContact NH2-OE1 3.17Å; R357-E371 IonicContact NH2-OE2 2.73Å; R357-E371 PolarHBondContact NH2-OE2 3.27Å; E371-H373 VanDerWaalsContact C-N 3.26Å; E371-H373 PolarHBondContact O-N 2.97Å; E371-L374 WeakPolarHBondContact O-CB 3.31Å; E371-L374 PolarHBondContact O-N 2.99Å; E371-L374 VanDerWaalsContact O-N 3.13Å; E371-A375 PolarHBondContact O-N 3.28Å
372P97.8Very high96.6Very high71 Ų7136 Ų3646%0.46120%0.201SC..Hα-helixtrans-57.9-34.4174.1-27.937.1000114.2P319 A370 A376P319-P372 HydrophobicContact CB-CB 3.67Å; P319-P372 HydrophobicContact CG-CB 3.82Å; A370-P372 VanDerWaalsContact C-CD 3.42Å; A370-P372 VanDerWaalsContact C-N 3.33Å; P372-A376 WeakPolarHBondContact O-CB 3.45Å; P372-A376 PolarHBondContact O-N 3.41Å
373H97.7Very high97Very high8 Ų835.9 Ų35.94%0.03721%0.207CC..Hα-helixtrans-72.2-36.5176.7-75.6-73.6000112.1F316 L369 A370 E371 A376 L377F316-H373 VanDerWaalsContact C-CE1 3.45Å; F316-H373 HydrophobicContact CD1-CB 4.17Å; F316-H373 AromaticContact CD1-ND1 3.92Å; F316-H373 PolarHBondContact O-CE1 3.48Å; F316-H373 PolarHBondContact O-NE2 3.2Å; L369-H373 HydrophobicContact CB-CB 4.41Å; L369-H373 HydrophobicContact CD2-CB 4.5Å; A370-H373 WeakPolarHBondContact O-CB 3.5Å; A370-H373 PolarHBondContact O-N 3.41Å; E371-H373 VanDerWaalsContact C-N 3.26Å; E371-H373 PolarHBondContact O-N 2.97Å; H373-A376 WeakPolarHBondContact O-CB 3.27Å; H373-A376 PolarHBondContact O-N 3.13Å; H373-L377 PolarHBondContact O-N 3.15Å
374L96.6Very high97.1Very high5 Ų535.7 Ų35.73%0.02621%0.206CC..Hα-helixtrans-63.4-44.9174.3-68.3173.5000110.6S353 M356 R357 L369 A370 E371 A376 L377S353-L374 VanDerWaalsContact CB-O 3.24Å; S353-L374 WeakPolarHBondContact CB-O 3.4Å; M356-L374 HydrophobicContact CB-CD2 3.87Å; M356-L374 HydrophobicContact CG-CD2 3.84Å; R357-L374 HydrophobicContact CB-CD1 4.25Å; R357-L374 HydrophobicContact CG-CD1 4.37Å; L369-L374 HydrophobicContact CB-CD2 4.45Å; L369-L374 HydrophobicContact CB-CG 4.39Å; L369-L374 HydrophobicContact CD1-CD2 4.14Å; A370-L374 PolarHBondContact O-N 3.17Å; E371-L374 WeakPolarHBondContact O-CB 3.31Å; E371-L374 PolarHBondContact O-N 2.99Å; E371-L374 VanDerWaalsContact O-N 3.13Å; L374-A376 VanDerWaalsContact C-N 3.31Å; L374-A376 PolarHBondContact O-N 3.38Å; L374-L377 HydrophobicContact CD2-CD1 4.35Å; L374-L377 WeakPolarHBondContact O-CB 3.35Å; L374-L377 PolarHBondContact O-N 2.92Å
375A97.3Very high97.2Very high55 Ų5533 Ų3346%0.45519%0.188SC..Hα-helixtrans-63.3-36.4173.900000112.7E371 L377 D378 R379E371-A375 PolarHBondContact O-N 3.28Å; A375-L377 VanDerWaalsContact C-N 3.32Å; A375-L377 PolarHBondContact O-N 3.45Å; A375-D378 PolarHBondContact O-N 3.15Å; A375-R379 PolarHBondContact O-N 3.33Å
376A97.9Very high97.2Very high0 Ų035 Ų350%021%0.205CC..Hα-helixtrans-63.8-35.3176.200000112.5P319 P372 H373 L374 D378 R379 R380P319-A376 HydrophobicContact CB-CB 4.45Å; P319-A376 WeakPolarHBondContact O-CB 3.32Å; P372-A376 WeakPolarHBondContact O-CB 3.45Å; P372-A376 PolarHBondContact O-N 3.41Å; H373-A376 WeakPolarHBondContact O-CB 3.27Å; H373-A376 PolarHBondContact O-N 3.13Å; L374-A376 VanDerWaalsContact C-N 3.31Å; L374-A376 PolarHBondContact O-N 3.38Å; A376-D378 PolarHBondContact O-N 2.79Å; A376-R379 PolarHBondContact O-N 2.76Å; A376-R380 WeakPolarHBondContact O-CB 3.43Å; A376-R380 WeakPolarHBondContact O-CD 3.21Å; A376-R380 WeakPolarHBondContact O-CG 3.39Å; A376-R380 PolarHBondContact O-N 2.86Å
377L97.1Very high97.4Very high0 Ų031.6 Ų31.60%019%0.187CC..Hα-helixtrans-58.4-46.5175.9-73.7170.3000111.9L153 L286 F316 L352 M356 H373 L374 A375 R380 L381L153-L377 HydrophobicContact CD2-CD2 4.39Å; L286-L377 HydrophobicContact CB-CD2 4.18Å; L286-L377 WeakPolarHBondContact O-CD2 3.43Å; F316-L377 HydrophobicContact CE1-CD1 4.4Å; F316-L377 HydrophobicContact CE1-CD2 4.04Å; F316-L377 HydrophobicContact CE1-CG 4.31Å; F316-L377 HydrophobicContact CZ-CD2 4.38Å; L352-L377 HydrophobicContact CD2-CB 3.9Å; L352-L377 HydrophobicContact CG-CB 4.13Å; M356-L377 HydrophobicContact CB-CD1 4.28Å; M356-L377 HydrophobicContact CG-CD1 3.94Å; H373-L377 PolarHBondContact O-N 3.15Å; L374-L377 HydrophobicContact CD2-CD1 4.35Å; L374-L377 WeakPolarHBondContact O-CB 3.35Å; L374-L377 PolarHBondContact O-N 2.92Å; A375-L377 VanDerWaalsContact C-N 3.32Å; A375-L377 PolarHBondContact O-N 3.45Å; L377-R380 PolarHBondContact O-N 3.5Å; L377-L381 WeakPolarHBondContact O-CB 3.11Å; L377-L381 PolarHBondContact O-N 3.41Å
378D97Very high97.4Very high27 Ų2727.5 Ų27.514%0.14416%0.16CC..Hα-helixtrans-65-41.2178.2-66.7-37.9000111.7G350 L352 S353 A375 A376 L381 N382G350-D378 WeakPolarHBondContact CA-OD2 3.43Å; L352-D378 WeakPolarHBondContact CB-OD1 3.47Å; S353-D378 WeakPolarHBondContact CB-OD2 3.42Å; S353-D378 PolarHBondContact N-OD1 3.45Å; S353-D378 PolarHBondContact OG-OD2 2.74Å; A375-D378 PolarHBondContact O-N 3.15Å; A376-D378 PolarHBondContact O-N 2.79Å; D378-L381 PolarHBondContact O-N 3.12Å; D378-N382 PolarHBondContact O-N 2.93Å; D378-N382 VanDerWaalsContact O-N 3.12Å; D378-N382 PolarHBondContact O-ND2 2.97Å
379R97.9Very high97.4Very high103 Ų10332.4 Ų32.439%0.38918%0.181SC..Hα-helixtrans-62.8-45.8177-172.6179.766.8-119.2-5.1111.4P319 D322 A375 A376 N382 G383P319-R379 PolarHBondContact O-NH1 3.22Å; P319-R379 PolarHBondContact O-NH2 2.88Å; D322-R379 IonicContact OD1-CZ 3.33Å; D322-R379 IonicContact OD1-NE 2.77Å; D322-R379 IonicContact OD1-NH2 3.38Å; D322-R379 PolarHBondContact OD1-NH2 2.9Å; D322-R379 IonicContact OD2-CZ 2.82Å; D322-R379 IonicContact OD2-NE 3.23Å; D322-R379 PolarHBondContact OD2-NE 3.45Å; D322-R379 IonicContact OD2-NH2 2.94Å; D322-R379 PolarHBondContact OD2-NH2 3.06Å; A375-R379 PolarHBondContact O-N 3.33Å; A376-R379 PolarHBondContact O-N 2.76Å; R379-N382 WeakPolarHBondContact O-CB 3.07Å; R379-N382 PolarHBondContact O-N 3.42Å; R379-G383 PolarHBondContact O-N 3.05Å; R379-G383 VanDerWaalsContact O-N 3.15Å
380R98.3Very high97.5Very high4 Ų436.9 Ų36.92%0.01520%0.202CC..Hα-helixtrans-65.4-40.1177-70.4165.1-176.4-179.9-1.7111.4Y285 L286 I287 N318 L321 D322 A376 L377 N382 G383 V384Y285-R380 HydrophobicContact CD1-CB 4.19Å; Y285-R380 HydrophobicContact CE1-CB 3.78Å; Y285-R380 HydrophobicContact CE1-CG 4.2Å; Y285-R380 WeakPolarHBondContact CE1-O 3.17Å; Y285-R380 WeakPolarHBondContact O-CD 3.27Å; L286-R380 HydrophobicContact CD2-CB 4.06Å; L286-R380 WeakPolarHBondContact O-CD 3.27Å; L286-R380 PolarHBondContact O-NH1 3.46Å; I287-R380 PolarHBondContact O-NH1 3.43Å; N318-R380 PolarHBondContact O-NH2 3.3Å; L321-R380 PolarHBondContact O-NH2 2.95Å; D322-R380 HydrophobicContact CB-CG 4.3Å; D322-R380 VanDerWaalsContact OD1-CG 3.23Å; D322-R380 WeakPolarHBondContact OD1-CG 3.34Å; D322-R380 IonicContact OD1-CZ 2.95Å; D322-R380 IonicContact OD1-NE 2.97Å; D322-R380 PolarHBondContact OD1-NE 3.44Å; D322-R380 IonicContact OD1-NH2 3.8Å; A376-R380 WeakPolarHBondContact O-CB 3.43Å; A376-R380 WeakPolarHBondContact O-CD 3.21Å; A376-R380 WeakPolarHBondContact O-CG 3.39Å; A376-R380 PolarHBondContact O-N 2.86Å; L377-R380 PolarHBondContact O-N 3.5Å; R380-N382 VanDerWaalsContact C-N 3.28Å; R380-N382 PolarHBondContact O-N 3.43Å; R380-G383 CarbonylContact O-C 3.59Å; R380-G383 WeakPolarHBondContact O-CA 3.22Å; R380-G383 PolarHBondContact O-N 2.93Å; R380-V384 PolarHBondContact O-N 2.92Å
381L97.3Very high97.5Very high1 Ų136.4 Ų36.41%0.00520%0.198CC..Hα-helixtrans-55.6-45.4174.1176.461000111.2L286 L344 L347 L352 L377 D378 G383 V384 I385L286-L381 HydrophobicContact CD2-CB 4.03Å; L344-L381 HydrophobicContact CB-CD1 4.03Å; L344-L381 HydrophobicContact CD2-CD1 3.63Å; L344-L381 HydrophobicContact CG-CD1 4.4Å; L347-L381 VanDerWaalsContact C-CD2 3.42Å; L347-L381 HydrophobicContact CB-CD2 3.58Å; L347-L381 WeakPolarHBondContact O-CD2 3.27Å; L352-L381 HydrophobicContact CB-CD2 4.1Å; L352-L381 HydrophobicContact CD2-CB 4.05Å; L352-L381 HydrophobicContact CD2-CD2 4.06Å; L377-L381 WeakPolarHBondContact O-CB 3.11Å; L377-L381 PolarHBondContact O-N 3.41Å; D378-L381 PolarHBondContact O-N 3.12Å; L381-G383 VanDerWaalsContact C-N 3.28Å; L381-G383 PolarHBondContact O-N 3.47Å; L381-V384 PolarHBondContact O-N 3.16Å; L381-I385 HydrophobicContact CD1-CD1 3.94Å; L381-I385 HydrophobicContact CD1-CG1 4.41Å; L381-I385 HydrophobicContact CG-CD1 3.77Å; L381-I385 VanDerWaalsContact O-CD1 3.3Å; L381-I385 WeakPolarHBondContact O-CD1 3.42Å; L381-I385 WeakPolarHBondContact O-CG1 3.05Å; L381-I385 PolarHBondContact O-N 3.24Å
382N97.5Very high97.6Very high89 Ų8933.6 Ų33.648%0.47619%0.185SC..Hα-helixtrans-60-38.3174.3-68.4-33.8000112.3D378 R379 R380 I385 A386D378-N382 PolarHBondContact O-N 2.93Å; D378-N382 VanDerWaalsContact O-N 3.12Å; D378-N382 PolarHBondContact O-ND2 2.97Å; R379-N382 WeakPolarHBondContact O-CB 3.07Å; R379-N382 PolarHBondContact O-N 3.42Å; R380-N382 VanDerWaalsContact C-N 3.28Å; R380-N382 PolarHBondContact O-N 3.43Å; N382-I385 PolarHBondContact O-N 3.11Å; N382-A386 WeakPolarHBondContact O-CB 3.41Å; N382-A386 PolarHBondContact O-N 3.09Å
383G97.8Very high97.5Very high22 Ų2237.9 Ų37.923%0.22720%0.199CC..Hα-helixtrans-57.6-49.117200000112.8R379 R380 L381 I385 A386 T387R379-G383 PolarHBondContact O-N 3.05Å; R379-G383 VanDerWaalsContact O-N 3.15Å; R380-G383 CarbonylContact O-C 3.59Å; R380-G383 WeakPolarHBondContact O-CA 3.22Å; R380-G383 PolarHBondContact O-N 2.93Å; L381-G383 VanDerWaalsContact C-N 3.28Å; L381-G383 PolarHBondContact O-N 3.47Å; G383-I385 PolarHBondContact O-N 3.31Å; G383-A386 PolarHBondContact O-N 2.77Å; G383-T387 PolarHBondContact O-N 3.31Å; G383-T387 PolarHBondContact O-OG1 3.12Å; G383-T387 VanDerWaalsContact O-OG1 3.13Å
384V98Very high97.4Very high0 Ų041.3 Ų41.30%023%0.229CC..Hα-helixtrans-58.4-49.1176.4178.90000110.8V282 Y285 L286 L327 L330 L344 R380 L381 A386 T387 V388V282-V384 HydrophobicContact CG1-CG1 3.96Å; V282-V384 HydrophobicContact CG1-CG2 4.3Å; V282-V384 HydrophobicContact CG2-CG1 3.96Å; Y285-V384 HydrophobicContact CD1-CG2 3.49Å; Y285-V384 VanDerWaalsContact CD1-CG2 3.49Å; Y285-V384 HydrophobicContact CE1-CG2 3.87Å; L286-V384 HydrophobicContact CD2-CG2 4.37Å; L327-V384 HydrophobicContact CD1-CG2 4.3Å; L327-V384 HydrophobicContact CD2-CG2 4.23Å; L330-V384 HydrophobicContact CD2-CG1 4.13Å; L344-V384 HydrophobicContact CD1-CG1 3.88Å; R380-V384 PolarHBondContact O-N 2.92Å; L381-V384 PolarHBondContact O-N 3.16Å; V384-A386 VanDerWaalsContact C-N 3.3Å; V384-A386 PolarHBondContact O-N 3Å; V384-T387 WeakPolarHBondContact O-CB 3.25Å; V384-T387 PolarHBondContact O-N 3.19Å; V384-V388 WeakPolarHBondContact O-CG2 3.32Å; V384-V388 PolarHBondContact O-N 3.18Å
385I97.5Very high97.3Very high8 Ų845.2 Ų45.24%0.04125%0.247CC..Hα-helixtrans-60.6-42.4-179.3-69.8150.7000111.1W341 K348 L381 N382 G383 T387 V388 K389W341-I385 HydrophobicContact CH2-CG2 4.06Å; W341-I385 HydrophobicContact CZ3-CB 4.46Å; W341-I385 HydrophobicContact CZ3-CG1 4.38Å; W341-I385 HydrophobicContact CZ3-CG2 4.24Å; K348-I385 HydrophobicContact CD-CD1 3.84Å; K348-I385 HydrophobicContact CG-CD1 3.43Å; K348-I385 VanDerWaalsContact CG-CD1 3.43Å; L381-I385 HydrophobicContact CD1-CD1 3.94Å; L381-I385 HydrophobicContact CD1-CG1 4.41Å; L381-I385 HydrophobicContact CG-CD1 3.77Å; L381-I385 VanDerWaalsContact O-CD1 3.3Å; L381-I385 WeakPolarHBondContact O-CD1 3.42Å; L381-I385 WeakPolarHBondContact O-CG1 3.05Å; L381-I385 PolarHBondContact O-N 3.24Å; N382-I385 PolarHBondContact O-N 3.11Å; G383-I385 PolarHBondContact O-N 3.31Å; I385-T387 VanDerWaalsContact C-N 3.34Å; I385-V388 PolarHBondContact O-N 2.83Å; I385-K389 HydrophobicContact CG2-CD 4.26Å; I385-K389 WeakPolarHBondContact O-CG 3.5Å; I385-K389 PolarHBondContact O-N 3.43Å
386A97.8Very high97.2Very high43 Ų4343.7 Ų43.736%0.35524%0.237SC..Hα-helixtrans-62.4-42.7177.300000111.2N382 G383 V384 K389 Q390N382-A386 WeakPolarHBondContact O-CB 3.41Å; N382-A386 PolarHBondContact O-N 3.09Å; G383-A386 PolarHBondContact O-N 2.77Å; V384-A386 VanDerWaalsContact C-N 3.3Å; V384-A386 PolarHBondContact O-N 3Å; A386-K389 PolarHBondContact O-N 2.94Å; A386-Q390 VanDerWaalsContact O-CG 3.31Å; A386-Q390 WeakPolarHBondContact O-CG 3.38Å; A386-Q390 PolarHBondContact O-N 2.06Å
387T98.1Very high96.9Very high10 Ų1046.7 Ų46.76%0.06126%0.257CS..Hα-helixtrans-61.6-45.4175.6-59.40000112.3L330 G383 V384 I385 K389 Q390 C391L330-T387 HydrophobicContact CD2-CG2 3.84Å; L330-T387 HydrophobicContact CG-CG2 3.99Å; G383-T387 PolarHBondContact O-N 3.31Å; G383-T387 PolarHBondContact O-OG1 3.12Å; G383-T387 VanDerWaalsContact O-OG1 3.13Å; V384-T387 WeakPolarHBondContact O-CB 3.25Å; V384-T387 PolarHBondContact O-N 3.19Å; I385-T387 VanDerWaalsContact C-N 3.34Å; T387-K389 VanDerWaalsContact C-N 3.35Å; T387-K389 PolarHBondContact O-N 2.88Å; T387-Q390 WeakPolarHBondContact O-CB 3.37Å; T387-Q390 PolarHBondContact O-N 2.97Å; T387-C391 PolarHBondContact O-N 2.52Å
388V97.8Very high96.6Very high1 Ų153.5 Ų53.51%0.00629%0.293CS..Hα-helixtrans-62.7-43.3177.2179.50000110.9L330 I336 W341 V384 I385 Q390 C391 M392 T400 L401L330-V388 HydrophobicContact CD1-CG2 4.19Å; L330-V388 HydrophobicContact CD2-CG2 3.98Å; I336-V388 HydrophobicContact CD1-CG2 4Å; I336-V388 HydrophobicContact CG2-CG1 3.92Å; I336-V388 HydrophobicContact CG2-CG2 4.29Å; W341-V388 HydrophobicContact CD2-CG1 4.19Å; W341-V388 HydrophobicContact CE3-CB 3.9Å; W341-V388 HydrophobicContact CE3-CG1 3.56Å; W341-V388 HydrophobicContact CE3-CG2 4.07Å; W341-V388 HydrophobicContact CH2-CB 4.31Å; W341-V388 HydrophobicContact CH2-CG1 4.17Å; W341-V388 HydrophobicContact CZ3-CB 3.53Å; W341-V388 HydrophobicContact CZ3-CG1 3.56Å; W341-V388 HydrophobicContact CZ3-CG2 4.03Å; V384-V388 WeakPolarHBondContact O-CG2 3.32Å; V384-V388 PolarHBondContact O-N 3.18Å; I385-V388 PolarHBondContact O-N 2.83Å; V388-Q390 VanDerWaalsContact C-N 3.33Å; V388-Q390 PolarHBondContact O-N 2.83Å; V388-C391 WeakPolarHBondContact O-CB 3.37Å; V388-C391 PolarHBondContact O-N 3.03Å; V388-C391 VanDerWaalsContact O-N 3.14Å; V388-M392 HydrophobicContact CG1-CG 4.34Å; V388-M392 HydrophobicContact CG1-SD 4.17Å; V388-M392 WeakPolarHBondContact O-CG 3.4Å; V388-M392 PolarHBondContact O-N 2.59Å; V388-T400 HydrophobicContact CG1-CG2 4.12Å; V388-L401 HydrophobicContact CG1-CD2 4.44Å
389K97.2Very high96.3Very high103 Ų10357.4 Ų57.445%0.44831%0.314SS..Hα-helixtrans-60-42.5176.7-75.4179.9174.4-171.90112.3W341 I385 A386 T387 C391 M392 E393W341-K389 HydrophobicContact CH2-CG 4.18Å; I385-K389 HydrophobicContact CG2-CD 4.26Å; I385-K389 WeakPolarHBondContact O-CG 3.5Å; I385-K389 PolarHBondContact O-N 3.43Å; A386-K389 PolarHBondContact O-N 2.94Å; T387-K389 VanDerWaalsContact C-N 3.35Å; T387-K389 PolarHBondContact O-N 2.88Å; K389-C391 VanDerWaalsContact C-N 3.3Å; K389-C391 PolarHBondContact O-N 3.21Å; K389-M392 WeakPolarHBondContact O-CB 3.47Å; K389-M392 PolarHBondContact O-N 3.42Å; K389-M392 VanDerWaalsContact O-N 3.17Å; K389-E393 WeakPolarHBondContact O-CG 3.48Å; K389-E393 PolarHBondContact O-N 3.38Å
390Q97.4Very high96.1Very high104 Ų10452.5 Ų52.549%0.48630%0.296SS..Hα-helixtrans-59.4-41.5174.6-73.1168.9300111.7A386 T387 V388 E393 A394A386-Q390 VanDerWaalsContact O-CG 3.31Å; A386-Q390 WeakPolarHBondContact O-CG 3.38Å; A386-Q390 PolarHBondContact O-N 2.06Å; T387-Q390 WeakPolarHBondContact O-CB 3.37Å; T387-Q390 PolarHBondContact O-N 2.97Å; V388-Q390 VanDerWaalsContact C-N 3.33Å; V388-Q390 PolarHBondContact O-N 2.83Å; Q390-E393 PolarHBondContact O-N 2.89Å; Q390-A394 WeakPolarHBondContact O-CB 3.46Å; Q390-A394 PolarHBondContact O-N 3.42Å
391C97.4Very high96Very high4 Ų454.1 Ų54.13%0.02730%0.304CS..Hα-helixtrans-64.2-42.2173.8-74.70000112.6C334 T387 V388 K389 E393 A394 Q395 T400C334-C391 WeakPolarHBondContact CA-SG 3.37Å; C334-C391 HydrophobicContact CB-CB 3.52Å; C334-C391 WeakPolarHBondContact CB-SG 3.35Å; C334-C391 VanDerWaalsContact SG-CA 3.59Å; C334-C391 WeakPolarHBondContact SG-CB 3.31Å; C334-C391 CovalentContact SG-SG 2.06Å; C334-C391 PolarHBondContact SG-SG 2.97Å; T387-C391 PolarHBondContact O-N 2.52Å; V388-C391 WeakPolarHBondContact O-CB 3.37Å; V388-C391 PolarHBondContact O-N 3.03Å; V388-C391 VanDerWaalsContact O-N 3.14Å; K389-C391 VanDerWaalsContact C-N 3.3Å; K389-C391 PolarHBondContact O-N 3.21Å; C391-E393 VanDerWaalsContact C-N 3.31Å; C391-E393 PolarHBondContact O-N 3.17Å; C391-A394 PolarHBondContact O-N 3.06Å; C391-Q395 PolarHBondContact O-N 2.97Å; C391-T400 HydrophobicContact CB-CG2 3.82Å; C391-T400 PolarHBondContact O-OG1 3.25Å
392M97.4Very high95.8Very high47 Ų4756.5 Ų56.523%0.23232%0.317CS..Hα-helixtrans-62.4-38.3175.9-66.1173.373.900112.1W341 V388 K389 G396 P397 T400 L401W341-M392 HydrophobicContact CZ2-SD 4.33Å; V388-M392 HydrophobicContact CG1-CG 4.34Å; V388-M392 HydrophobicContact CG1-SD 4.17Å; V388-M392 WeakPolarHBondContact O-CG 3.4Å; V388-M392 PolarHBondContact O-N 2.59Å; K389-M392 WeakPolarHBondContact O-CB 3.47Å; K389-M392 PolarHBondContact O-N 3.42Å; K389-M392 VanDerWaalsContact O-N 3.17Å; M392-G396 CarbonylContact O-C 3.47Å; M392-G396 WeakPolarHBondContact O-CA 3.24Å; M392-G396 PolarHBondContact O-N 3.29Å; M392-P397 HydrophobicContact CE-CB 3.71Å; M392-T400 HydrophobicContact CG-CG2 3.83Å; M392-T400 PolarHBondContact N-OG1 2.94Å; M392-L401 HydrophobicContact CE-CD1 3.98Å
393E97.3Very high95.3Very high161 Ų16158.2 Ų58.275%0.75232%0.321SS*.Hα-helixtrans-68-37.8175.3-73.1169-17000111.9K389 Q390 C391K389-E393 WeakPolarHBondContact O-CG 3.48Å; K389-E393 PolarHBondContact O-N 3.38Å; Q390-E393 PolarHBondContact O-N 2.89Å; C391-E393 VanDerWaalsContact C-N 3.31Å; C391-E393 PolarHBondContact O-N 3.17Å
394A95.3Very high93.9Very high81 Ų8159.5 Ų59.567%0.66932%0.323SS*.Hα-helixtrans-78.9-39.3-177.300000114Q390 C391Q390-A394 WeakPolarHBondContact O-CB 3.46Å; Q390-A394 PolarHBondContact O-N 3.42Å; C391-A394 PolarHBondContact O-N 3.06Å
395Q94.7Very high91.9Very high86 Ų8668.7 Ų68.740%0.40236%0.358SS..Hα-helixtrans-121.2-6.9-170.3-57.9-174.27.500113.9C391 N399C391-Q395 PolarHBondContact O-N 2.97Å; Q395-N399 HydrophobicContact CB-CB 4.38Å; Q395-N399 PolarHBondContact O-ND2 3.45Å
396G94.6Very high89.7Confident24 Ų2471.5 Ų71.525%0.24737%0.372CS..  trans89.4153.9-174.900000113.1M392 D398 N399 T400M392-G396 CarbonylContact O-C 3.47Å; M392-G396 WeakPolarHBondContact O-CA 3.24Å; M392-G396 PolarHBondContact O-N 3.29Å; G396-D398 PolarHBondContact O-N 3.19Å; G396-N399 PolarHBondContact O-N 2.95Å; G396-T400 PolarHBondContact O-N 3.02Å; G396-T400 PolarHBondContact O-OG1 2.92Å
397P92.5Very high87Confident63 Ų6376.9 Ų76.941%0.40940%0.395SS..Hα-helixtrans-64.1-39.1-176.525.6-34.6000112.7M392 N399 T400 L401M392-P397 HydrophobicContact CE-CB 3.71Å; P397-N399 VanDerWaalsContact C-N 3.29Å; P397-N399 PolarHBondContact O-N 2.81Å; P397-T400 PolarHBondContact O-N 3.36Å; P397-T400 VanDerWaalsContact O-N 3.17Å; P397-L401 WeakPolarHBondContact O-CB 3.37Å; P397-L401 PolarHBondContact O-N 2.66Å
398D90.4Very high84.1Confident142 Ų14280.5 Ų80.576%0.75941%0.413SS*.Hα-helixtrans-68.1-29.4-176.1-60.4-24000112.6G396G396-D398 PolarHBondContact O-N 3.19Å
399N90.9Very high80.9Confident109 Ų10986.2 Ų86.258%0.58345%0.45SS*.Hα-helixtrans-84.6-21.7176.3-65.7-39.9000112.4Q395 G396 P397Q395-N399 HydrophobicContact CB-CB 4.38Å; Q395-N399 PolarHBondContact O-ND2 3.45Å; G396-N399 PolarHBondContact O-N 2.95Å; P397-N399 VanDerWaalsContact C-N 3.29Å; P397-N399 PolarHBondContact O-N 2.81Å
400T94.2Very high77.6Confident1 Ų189.3 Ų89.31%0.00647%0.466CS..Hα-helixtrans-91.9-39.5-178.5-550000112.1C334 M335 I336 V388 C391 M392 G396 P397C334-T400 VanDerWaalsContact O-CA 3.31Å; C334-T400 WeakPolarHBondContact O-CA 3.34Å; M335-T400 CarbonylContact C-O 3.6Å; M335-T400 VanDerWaalsContact CA-O 3.3Å; M335-T400 WeakPolarHBondContact CA-O 3.27Å; I336-T400 HydrophobicContact CG2-CG2 4.5Å; I336-T400 PolarHBondContact N-O 3.11Å; V388-T400 HydrophobicContact CG1-CG2 4.12Å; C391-T400 HydrophobicContact CB-CG2 3.82Å; C391-T400 PolarHBondContact O-OG1 3.25Å; M392-T400 HydrophobicContact CG-CG2 3.83Å; M392-T400 PolarHBondContact N-OG1 2.94Å; G396-T400 PolarHBondContact O-N 3.02Å; G396-T400 PolarHBondContact O-OG1 2.92Å; P397-T400 PolarHBondContact O-N 3.36Å; P397-T400 VanDerWaalsContact O-N 3.17Å
401L94.8Very high74.6Confident38 Ų3893.8 Ų93.820%0.19950%0.504CS..EExtended strand (participates in β ladder)trans-98.6102.1-175.4-60.5-178.4000110.1I336 V338 W341 V388 M392 P397I336-L401 HydrophobicContact CG2-CD2 3.73Å; V338-L401 HydrophobicContact CG2-CB 3.88Å; W341-L401 HydrophobicContact CB-CD2 3.89Å; W341-L401 HydrophobicContact CD2-CD2 4.3Å; W341-L401 HydrophobicContact CG-CD2 3.74Å; V388-L401 HydrophobicContact CG1-CD2 4.44Å; M392-L401 HydrophobicContact CE-CD1 3.98Å; P397-L401 WeakPolarHBondContact O-CB 3.37Å; P397-L401 PolarHBondContact O-N 2.66Å
402I93.6Very high73.5Confident51 Ų5198.3 Ų98.326%0.26253%0.528SS..EExtended strand (participates in β ladder)trans-93.3120.5-174.9-50.8-56.1000110.3L275 M335 I336 R337 V338 D404L275-I402 HydrophobicContact CD1-CB 4.26Å; L275-I402 HydrophobicContact CD1-CG2 3.95Å; L275-I402 HydrophobicContact CD2-CB 4.24Å; L275-I402 HydrophobicContact CD2-CG1 4.28Å; M335-I402 HydrophobicContact CB-CG1 4.02Å; M335-I402 HydrophobicContact CE-CG1 4.27Å; I336-I402 PolarHBondContact O-N 3.33Å; R337-I402 WeakPolarHBondContact CA-O 3.14Å; V338-I402 PolarHBondContact N-O 3.1Å; I402-D404 PolarHBondContact O-N 3.02Å
403E86.7Confident72.2Confident124 Ų124100.9 Ų100.958%0.57954%0.543SS*.  trans-73.6105.4167-77.6-164.517800109.4V338 R405V338-E403 HydrophobicContact CG2-CG 4.11Å; E403-R405 PolarHBondContact O-N 3.19Å; E403-R405 VanDerWaalsContact O-N 3.13Å; E403-R405 IonicContact OE2-CZ 2.8Å; E403-R405 IonicContact OE2-NE 2.69Å; E403-R405 PolarHBondContact OE2-NE 3Å; E403-R405 IonicContact OE2-NH2 3.1Å; E403-R405 PolarHBondContact OE2-NH2 3.04Å
404D69.3Low70.8Confident50 Ų5097.6 Ų97.627%0.26753%0.532SS..  trans-84.386.9171.3-163.21000109L275 R337 I402 M406L275-D404 HydrophobicContact CD1-CB 4.37Å; R337-D404 HydrophobicContact CG-CB 3.89Å; R337-D404 IonicContact CZ-OD2 3.69Å; R337-D404 VanDerWaalsContact CZ-OD2 3.23Å; R337-D404 VanDerWaalsContact NE-CB 3.26Å; R337-D404 IonicContact NE-OD2 3.67Å; R337-D404 PolarHBondContact NE-OD2 3.27Å; R337-D404 IonicContact NH2-OD2 2.79Å; R337-D404 PolarHBondContact NH2-OD2 3.34Å; I402-D404 PolarHBondContact O-N 3.02Å; D404-M406 PolarHBondContact O-N 3.23Å; D404-M406 VanDerWaalsContact OD1-CG 3.23Å; D404-M406 WeakPolarHBondContact OD1-CG 3.5Å
405R54.6Low69.4Low193 Ų19398.6 Ų98.673%0.72852%0.524SS*.  trans-79.471.5168-64.3-174.2-171.4-1742.7108.6E403 N407E403-R405 PolarHBondContact O-N 3.19Å; E403-R405 VanDerWaalsContact O-N 3.13Å; E403-R405 IonicContact OE2-CZ 2.8Å; E403-R405 IonicContact OE2-NE 2.69Å; E403-R405 PolarHBondContact OE2-NE 3Å; E403-R405 IonicContact OE2-NH2 3.1Å; E403-R405 PolarHBondContact OE2-NH2 3.04Å; R405-N407 VanDerWaalsContact C-N 3.33Å; R405-N407 PolarHBondContact O-N 3.22Å
406M52.8Low67.8Low66 Ų6699.4 Ų99.433%0.32553%0.531SS..  trans-66.8101.2163.6-68.8-161.4-6300107.5R74 P272 D404 L408R74-M406 HydrophobicContact CG-CE 4.17Å; P272-M406 HydrophobicContact CB-SD 4.08Å; P272-M406 HydrophobicContact CG-SD 4.07Å; D404-M406 PolarHBondContact O-N 3.23Å; D404-M406 VanDerWaalsContact OD1-CG 3.23Å; D404-M406 WeakPolarHBondContact OD1-CG 3.5Å; M406-L408 HydrophobicContact CB-CD2 4.41Å; M406-L408 HydrophobicContact CB-CG 4.17Å; M406-L408 PolarHBondContact O-N 3.12Å
407N39.6Very low66Low157 Ų157104.4 Ų104.484%0.8455%0.55SS**  trans-67.380158.2-75-20.1000106.4R405 P409R405-N407 VanDerWaalsContact C-N 3.33Å; R405-N407 PolarHBondContact O-N 3.22Å; N407-P409 VanDerWaalsContact O-CD 3.25Å; N407-P409 WeakPolarHBondContact O-CD 3.35Å
408L38.3Very low64.2Low85 Ų85107.4 Ų107.445%0.44556%0.56SS.*  trans-64.4119.7167.3-67171.7000105.9R74 M406 H410R74-L408 HydrophobicContact CG-CD2 4.02Å; M406-L408 HydrophobicContact CB-CD2 4.41Å; M406-L408 HydrophobicContact CB-CG 4.17Å; M406-L408 PolarHBondContact O-N 3.12Å; L408-H410 VanDerWaalsContact C-N 3.32Å; L408-H410 PolarHBondContact O-N 3.42Å
409P29.2Very low62.1Low121 Ų121104.7 Ų104.779%0.78655%0.545SS*.  trans-60.7108161.525.6-27.8000105N407N407-P409 VanDerWaalsContact O-CD 3.25Å; N407-P409 WeakPolarHBondContact O-CD 3.35Å
410H28.7Very low59.7Low168 Ų168104.3 Ų104.378%0.77854%0.542SS*.  trans-54.9135.8167.6-70.9-60.9000107.5L408L408-H410 VanDerWaalsContact C-N 3.32Å; L408-H410 PolarHBondContact O-N 3.42Å
411P35.1Very low56.6Low198 Ų198113.7 Ų113.7100%1.28659%0.59SS**  trans-59.60165.725.5-31.3000111.3

Retrieved 411 of 411 residues in 106.1 ms (Link to these results)