A0A087Y9C4_POEFO Loading...

Carboxypeptidase A1

AlphaFold DB , UniProt , Accession A0A087Y9C4, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 601 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40.5Very low32.3Very low244 Ų244154.8 Ų154.8100%1.20285%0.852SS**  0134.10-87.1177.6174.900107.9
2M36.1Very low32.3Very low188 Ų188158.8 Ų158.893%0.92686%0.855SS**  trans71.1122.2-159.8-68.2177.690.400116.5
3R31.3Very low32.1Very low254 Ų254152.9 Ų152.996%0.95883%0.828SS**  171138.1121.9-94.1179.1179.8-164.10.2111.9
4G28.8Very low32.2Very low78 Ų78147.5 Ų147.580%0.80481%0.814SS**  trans114.8108.4132.200000118.9
5L38.3Very low32.3Very low164 Ų164144.3 Ų144.386%0.85980%0.8SS**  trans-56.3151.4156-87.277.4000112.2
6I29.4Very low32.6Very low172 Ų172146.3 Ų146.388%0.88281%0.807SS**  179.5141.8113.1-84.7158000109.9
7A33.9Very low33Very low83 Ų83141.9 Ų141.969%0.68680%0.795SS**  trans-78.4159.6-168.800000116.6
8F30.8Very low34.3Very low208 Ų208141.3 Ų141.391%0.91278%0.783SS**  trans-163.399.9138.1-108.9-85.7000106.7
9A28.7Very low36Very low79 Ų79141.3 Ų141.365%0.65378%0.776SS**  66.484.298.700000114.7
10A29.5Very low38.1Very low89 Ų89138.1 Ų138.174%0.73676%0.761SS**  trans-139.575137.100000104.4F12A10-F12 PolarHBondContact O-N 2.64Å; A10-F12 VanDerWaalsContact O-N 3.12Å
11L28.6Very low40.5Very low144 Ų144133.3 Ų133.375%0.75473%0.733SS**  28.463.289-129.397.5000111.1V13L11-V13 HydrophobicContact CD2-CB 4.02Å; L11-V13 HydrophobicContact CD2-CG2 3.29Å; L11-V13 HydrophobicContact CG-CB 4.41Å; L11-V13 HydrophobicContact CG-CG2 3.69Å; L11-V13 PolarHBondContact O-N 2.97Å
12F32.1Very low42.9Very low202 Ų202127.9 Ų127.989%0.88671%0.705SS**  trans-67.671.2144.3-106.6-86.5000106.6A10 A14A10-F12 PolarHBondContact O-N 2.64Å; A10-F12 VanDerWaalsContact O-N 3.12Å; F12-A14 PolarHBondContact O-N 3.42Å
13V29.6Very low45.3Very low83 Ų83120.4 Ų120.450%0.50368%0.675SS.*  trans-6280.9137.2163.70000103.8L11 V15L11-V13 HydrophobicContact CD2-CB 4.02Å; L11-V13 HydrophobicContact CD2-CG2 3.29Å; L11-V13 HydrophobicContact CG-CB 4.41Å; L11-V13 HydrophobicContact CG-CG2 3.69Å; L11-V13 PolarHBondContact O-N 2.97Å; V13-V15 HydrophobicContact CG1-CB 4.02Å; V13-V15 HydrophobicContact CG1-CG2 3.1Å; V13-V15 VanDerWaalsContact CG1-N 3.33Å; V13-V15 PolarHBondContact O-N 2.84Å
14A32.8Very low48.3Very low77 Ų77109.4 Ų109.464%0.63664%0.635SS**  trans-6387.7132.700000102.4F12 L16F12-A14 PolarHBondContact O-N 3.42Å; A14-L16 PolarHBondContact O-N 3.02Å
15V33.9Very low51.4Low99 Ų99107.2 Ų107.260%0.660%0.603SS**  trans-46.8123.9152.7-171.10000101.6V13 A17V13-V15 HydrophobicContact CG1-CB 4.02Å; V13-V15 HydrophobicContact CG1-CG2 3.1Å; V13-V15 VanDerWaalsContact CG1-N 3.33Å; V13-V15 PolarHBondContact O-N 2.84Å; V15-A17 HydrophobicContact CB-CB 3.97Å; V15-A17 HydrophobicContact CG1-CB 3.84Å; V15-A17 PolarHBondContact O-N 3Å
16L38Very low54Low176 Ų17699.6 Ų99.692%0.92156%0.564SS**  trans-61.660.3154.2-74.4153.5000106.7A14 K18A14-L16 PolarHBondContact O-N 3.02Å; L16-K18 PolarHBondContact O-N 2.88Å
17A39.3Very low56.9Low73 Ų7391.4 Ų91.460%0.60352%0.522SS*.  trans-73.597.7169.800000101.4V15 E19V15-A17 HydrophobicContact CB-CB 3.97Å; V15-A17 HydrophobicContact CG1-CB 3.84Å; V15-A17 PolarHBondContact O-N 3Å; A17-E19 PolarHBondContact O-N 2.88Å
18K55.5Low59.7Low130 Ų13090.9 Ų90.957%0.56550%0.502SS*.  trans-48.9113.9167.1-156.9-179-163.6-169.20105.2L16 T20 R102L16-K18 PolarHBondContact O-N 2.88Å; K18-T20 PolarHBondContact O-N 2.86Å; K18-R102 VanDerWaalsContact CE-NH2 3.34Å
19E66.1Low62.6Low141 Ų14181 Ų8166%0.65946%0.459SS*.  trans-56.4127.1179.1-156.1176.1-178.400107.4A17 F21A17-E19 PolarHBondContact O-N 2.88Å; E19-F21 HydrophobicContact CG-CZ 4.48Å
20T79.9Confident65.3Low77 Ų7779.9 Ų79.947%0.47244%0.444SS..  trans-106.2137.8179.956.40000108.6K18K18-T20 PolarHBondContact O-N 2.86Å
21F88.3Confident68.1Low38 Ų3875.7 Ų75.717%0.16741%0.409CS..  trans-103.928.7179.6-59.4-78.6000111.5E19 G23 H24 V94 Q95 L98E19-F21 HydrophobicContact CG-CZ 4.48Å; F21-G23 PolarHBondContact O-N 2.61Å; F21-H24 WeakPolarHBondContact CA-CD2 3.45Å; F21-H24 HydrophobicContact CB-CB 4.22Å; F21-H24 WeakPolarHBondContact O-CB 3.2Å; F21-H24 PolarHBondContact O-CD2 3.27Å; F21-H24 PolarHBondContact O-N 2.67Å; F21-V94 HydrophobicContact CB-CB 3.99Å; F21-V94 HydrophobicContact CB-CG1 3.84Å; F21-V94 HydrophobicContact CG-CG1 4.21Å; F21-Q95 HydrophobicContact CB-CB 4.47Å; F21-Q95 PolarHBondContact O-N 3.28Å; F21-L98 HydrophobicContact CB-CD1 4.45Å; F21-L98 HydrophobicContact CD2-CD1 3.38Å; F21-L98 HydrophobicContact CE2-CD1 3.98Å; F21-L98 HydrophobicContact CG-CD1 4.22Å
22E89.6Confident71Confident131 Ų13173.1 Ų73.161%0.61239%0.392SS*.THydrogen-bonded Turntrans-56.9120.7-176.7-73-177.7-173.300109.8H24 Q95E22-H24 PolarHBondContact O-N 3.02Å; E22-Q95 HydrophobicContact CB-CB 4.45Å; E22-Q95 HydrophobicContact CG-CB 4.01Å; E22-Q95 HydrophobicContact CG-CG 3.72Å
23G87.4Confident73.8Confident30 Ų3066.9 Ų66.931%0.30937%0.368SS..THydrogen-bonded Turntrans73.36.6178.800000115.1F21 D93F21-G23 PolarHBondContact O-N 2.61Å; G23-D93 PolarHBondContact N-OD1 3.39Å; G23-D93 VanDerWaalsContact N-OD1 3.15Å
24H93.4Very high76.5Confident23 Ų2369.2 Ų69.211%0.10637%0.373CS..  trans-67.8137167.2-72.8-117.5000109.4F21 E22 R67 V68 P69 P70 D93 V94F21-H24 WeakPolarHBondContact CA-CD2 3.45Å; F21-H24 HydrophobicContact CB-CB 4.22Å; F21-H24 WeakPolarHBondContact O-CB 3.2Å; F21-H24 PolarHBondContact O-CD2 3.27Å; F21-H24 PolarHBondContact O-N 2.67Å; E22-H24 PolarHBondContact O-N 3.02Å; H24-R67 HydrophobicContact CB-CG 4.18Å; H24-R67 PolarHBondContact CE1-NH1 3.1Å; H24-R67 PolarHBondContact ND1-NH1 3.14Å; H24-V68 WeakPolarHBondContact CA-O 3.47Å; H24-P69 WeakPolarHBondContact ND1-CA 3.46Å; H24-P70 WeakPolarHBondContact CD2-CD 3.38Å; H24-P70 WeakPolarHBondContact NE2-CD 3.38Å; H24-D93 WeakPolarHBondContact O-CA 3.46Å; H24-V94 HydrophobicContact CB-CB 4.13Å; H24-V94 HydrophobicContact CB-CG2 4.12Å; H24-V94 WeakPolarHBondContact O-CG2 3.26Å; H24-V94 PolarHBondContact O-N 3.36Å
25Q93.9Very high79.1Confident32 Ų3271.6 Ų71.615%0.1537%0.374CS..EExtended strand (participates in β ladder)trans-110.1151175.1-63.7-160.3-30.100111L27 R67 V68 L73 T89 I91 E92Q25-L27 HydrophobicContact CB-CD2 4.29Å; Q25-R67 CarbonylContact O-C 3.53Å; Q25-R67 WeakPolarHBondContact O-CA 3.38Å; Q25-V68 PolarHBondContact N-O 2.64Å; Q25-V68 VanDerWaalsContact N-O 3.14Å; Q25-V68 PolarHBondContact O-N 2.67Å; Q25-L73 HydrophobicContact CB-CD1 3.93Å; Q25-L73 HydrophobicContact CB-CD2 4.36Å; Q25-L73 HydrophobicContact CG-CD1 4.23Å; Q25-L73 HydrophobicContact CG-CD2 3.75Å; Q25-T89 HydrophobicContact CB-CG2 4.42Å; Q25-I91 CarbonylContact C-O 3.58Å; Q25-I91 VanDerWaalsContact CA-O 3.27Å; Q25-I91 WeakPolarHBondContact CA-O 3.36Å; Q25-E92 WeakPolarHBondContact CG-O 3.27Å; Q25-E92 PolarHBondContact NE2-O 2.85Å
26V92.6Very high81.7Confident4 Ų467.2 Ų67.22%0.02435%0.347CS..EExtended strand (participates in β ladder)trans-105120.1165.3-1780000108.3W54 D65 V66 R67 M90 I91 V94V26-W54 HydrophobicContact CG1-CE3 4.12Å; V26-W54 HydrophobicContact CG1-CZ3 4.45Å; V26-W54 HydrophobicContact CG2-CD2 4.33Å; V26-W54 HydrophobicContact CG2-CE3 4.03Å; V26-W54 HydrophobicContact CG2-CH2 3.67Å; V26-W54 HydrophobicContact CG2-CZ2 3.98Å; V26-W54 HydrophobicContact CG2-CZ3 3.7Å; V26-D65 HydrophobicContact CG1-CB 4.44Å; V26-V66 CarbonylContact C-O 3.54Å; V26-V66 WeakPolarHBondContact CA-O 3.35Å; V26-R67 HydrophobicContact CG2-CB 4.17Å; V26-M90 HydrophobicContact CB-CB 4.38Å; V26-M90 HydrophobicContact CG1-CB 4.28Å; V26-M90 WeakPolarHBondContact O-CB 3.46Å; V26-M90 PolarHBondContact O-N 2.6Å; V26-I91 HydrophobicContact CB-CB 3.94Å; V26-I91 HydrophobicContact CB-CD1 4.32Å; V26-I91 HydrophobicContact CB-CG1 4.14Å; V26-I91 HydrophobicContact CG2-CB 4.02Å; V26-I91 HydrophobicContact CG2-CD1 3.96Å; V26-I91 HydrophobicContact CG2-CG1 4.25Å; V26-I91 PolarHBondContact N-O 2.77Å; V26-I91 PolarHBondContact O-N 2.9Å; V26-V94 HydrophobicContact CG2-CG2 3.75Å
27L91.9Very high83.8Confident0 Ų059 Ų590%030%0.304CS..EExtended strand (participates in β ladder)trans-104137.1177.1-54.8-173.9000109.5Q25 D65 V66 V68 L73 F76 K77 L80 Y87 T89Q25-L27 HydrophobicContact CB-CD2 4.29Å; L27-D65 WeakPolarHBondContact O-CA 3.34Å; L27-V66 HydrophobicContact CB-CG2 4.29Å; L27-V66 PolarHBondContact N-O 3.35Å; L27-V66 PolarHBondContact O-N 3.09Å; L27-V68 HydrophobicContact CD1-CG2 4.04Å; L27-V68 HydrophobicContact CG-CG2 4.08Å; L27-L73 HydrophobicContact CD1-CD1 4.32Å; L27-F76 HydrophobicContact CD1-CD1 4.06Å; L27-F76 HydrophobicContact CD1-CE1 4.2Å; L27-K77 HydrophobicContact CD1-CG 4.23Å; L27-L80 HydrophobicContact CD1-CD1 4.28Å; L27-Y87 HydrophobicContact CD1-CD2 4.12Å; L27-Y87 HydrophobicContact CD1-CE2 4.44Å; L27-Y87 HydrophobicContact CD2-CD2 4.27Å; L27-T89 HydrophobicContact CD2-CG2 4.26Å; L27-T89 WeakPolarHBondContact CD2-OG1 3.21Å
28R91.1Very high85.9Confident73 Ų7358.3 Ų58.328%0.27530%0.299SS..EExtended strand (participates in β ladder)trans-100.9124.5167.8171.8163.9-69.81721.1109P63 V64 D65 Y87 S88 M90R28-P63 HydrophobicContact CG-CB 3.92Å; R28-V64 CarbonylContact C-O 3.6Å; R28-V64 WeakPolarHBondContact CA-O 3.46Å; R28-D65 WeakPolarHBondContact CA-OD1 3.41Å; R28-D65 VanDerWaalsContact CB-OD1 3.25Å; R28-D65 WeakPolarHBondContact CB-OD1 3.11Å; R28-D65 WeakPolarHBondContact CG-OD1 3.37Å; R28-D65 IonicContact CZ-OD1 2.72Å; R28-D65 IonicContact CZ-OD2 3.88Å; R28-D65 IonicContact NE-OD1 2.91Å; R28-D65 PolarHBondContact NE-OD1 3.28Å; R28-D65 IonicContact NE-OD2 2.96Å; R28-D65 IonicContact NH2-OD1 3.24Å; R28-D65 PolarHBondContact NH2-OD1 3.15Å; R28-D65 IonicContact NH2-OD2 3.44Å; R28-D65 PolarHBondContact NH2-OD2 3.48Å; R28-Y87 CarbonylContact O-C 3.59Å; R28-Y87 WeakPolarHBondContact O-CA 3.08Å; R28-Y87 WeakPolarHBondContact O-CB 3.48Å; R28-S88 PolarHBondContact N-O 2.87Å; R28-S88 PolarHBondContact O-N 2.8Å; R28-M90 HydrophobicContact CB-CG 3.57Å; R28-M90 HydrophobicContact CB-SD 4.13Å
29I91.6Very high87.3Confident0 Ų054 Ų540%028%0.281CS..EExtended strand (participates in β ladder)trans-120133.7-177-52160.7000108L40 P63 V64 V66 F76 L80 L85I29-L40 HydrophobicContact CB-CD1 4.33Å; I29-L40 HydrophobicContact CD1-CD2 3.94Å; I29-L40 HydrophobicContact CG2-CD1 3.77Å; I29-L40 HydrophobicContact CG2-CD2 4.13Å; I29-P63 WeakPolarHBondContact O-CA 3.49Å; I29-V64 PolarHBondContact N-O 3.39Å; I29-V64 PolarHBondContact O-N 2.72Å; I29-V66 HydrophobicContact CD1-CG2 3.81Å; I29-F76 HydrophobicContact CD1-CE1 4.07Å; I29-F76 HydrophobicContact CD1-CZ 3.93Å; I29-L80 HydrophobicContact CD1-CD1 3.89Å; I29-L80 HydrophobicContact CD1-CD2 3.85Å; I29-L80 HydrophobicContact CG1-CD1 4.06Å; I29-L80 HydrophobicContact CG1-CD2 4.45Å; I29-L80 HydrophobicContact CG2-CD2 4.43Å; I29-L85 HydrophobicContact CG2-CB 4.21Å; I29-L85 HydrophobicContact CG2-CD2 4.07Å
30V86.2Confident87.9Confident56 Ų5648.2 Ų48.234%0.33926%0.255SS..  trans-118.6102.9179.4-174.90000109.7K32 P63 E86V30-K32 PolarHBondContact O-N 2.98Å; V30-P63 HydrophobicContact CG2-CB 4.36Å; V30-E86 PolarHBondContact N-O 3.03Å
31P87.9Confident87.7Confident0 Ų049.8 Ų49.80%026%0.255CS..  trans-71.1128.5179.728-31.6000110.5Q36 L37 L40 S61 Y62P31-Q36 HydrophobicContact CB-CB 3.9Å; P31-L37 HydrophobicContact CB-CB 4.36Å; P31-L37 HydrophobicContact CB-CD1 4.15Å; P31-L37 HydrophobicContact CG-CD1 3.51Å; P31-L40 HydrophobicContact CB-CD1 4.05Å; P31-L40 HydrophobicContact CG-CD1 4.1Å; P31-S61 WeakPolarHBondContact O-CA 3.16Å; P31-S61 PolarHBondContact O-N 3.05Å; P31-Y62 VanDerWaalsContact CD-O 3.31Å; P31-Y62 WeakPolarHBondContact CD-O 2.89Å
32K90.9Very high87.2Confident91 Ų9150.6 Ų50.640%0.39626%0.261SS..  trans-86.3-17.3-178.1-61.7174.7-177.6168.20113.4V30 V60 E86V30-K32 PolarHBondContact O-N 2.98Å; K32-V60 VanDerWaalsContact C-CG1 3.42Å; K32-V60 VanDerWaalsContact O-CG1 3.31Å; K32-V60 WeakPolarHBondContact O-CG1 3.45Å; K32-E86 VanDerWaalsContact CE-CD 3.43Å; K32-E86 WeakPolarHBondContact CE-OE1 3.43Å; K32-E86 WeakPolarHBondContact CE-OE2 3.26Å; K32-E86 IonicContact NZ-OE1 2.69Å; K32-E86 PolarHBondContact NZ-OE1 2.87Å; K32-E86 IonicContact NZ-OE2 3.14Å
33N89.3Confident85.7Confident71 Ų7151.7 Ų51.738%0.3827%0.267SS..SBendtrans-151.9171.4-178.260.859.8000112.1L35 Q36 L37N33-L35 VanDerWaalsContact C-N 3.26Å; N33-L35 PolarHBondContact O-N 3.46Å; N33-L35 WeakPolarHBondContact OD1-CB 3.49Å; N33-L35 PolarHBondContact OD1-N 3.45Å; N33-Q36 PolarHBondContact O-N 3.45Å; N33-Q36 PolarHBondContact OD1-N 3.25Å; N33-L37 PolarHBondContact O-N 3.22Å
34E86.3Confident84.5Confident132 Ų13257.3 Ų57.362%0.61729%0.285SS*.Hα-helixtrans-63-28.6-178.1-69.7-65.1163.900113.7L37 A38 V60E34-L37 WeakPolarHBondContact O-CB 3.5Å; E34-L37 PolarHBondContact O-N 3.43Å; E34-L37 WeakPolarHBondContact OE2-CD2 3.46Å; E34-A38 WeakPolarHBondContact O-CB 3.37Å; E34-A38 PolarHBondContact O-N 3.03Å; E34-V60 HydrophobicContact CG-CG2 3.99Å; E34-V60 WeakPolarHBondContact OE1-CG2 3.42Å
35L87.9Confident83.5Confident126 Ų12658 Ų5866%0.6629%0.288SS*.Hα-helixtrans-71.4-44.7178.4-174.2137.1000110.7N33 L37 A38 L39N33-L35 VanDerWaalsContact C-N 3.26Å; N33-L35 PolarHBondContact O-N 3.46Å; N33-L35 WeakPolarHBondContact OD1-CB 3.49Å; N33-L35 PolarHBondContact OD1-N 3.45Å; L35-L37 VanDerWaalsContact C-N 3.32Å; L35-L37 PolarHBondContact O-N 3.5Å; L35-A38 PolarHBondContact O-N 2.86Å; L35-L39 HydrophobicContact CD2-CD1 4.24Å; L35-L39 WeakPolarHBondContact O-CG 3.3Å; L35-L39 PolarHBondContact O-N 2.93Å; L35-L39 VanDerWaalsContact O-N 3.09Å
36Q88.3Confident82.4Confident7 Ų758.8 Ų58.83%0.03329%0.293CS..Hα-helixtrans-62.5-39.3171.6-78.1-176.3-10.600112.4P31 N33 A38 L39 L40 H83 D84 L85P31-Q36 HydrophobicContact CB-CB 3.9Å; N33-Q36 PolarHBondContact O-N 3.45Å; N33-Q36 PolarHBondContact OD1-N 3.25Å; Q36-A38 VanDerWaalsContact C-N 3.31Å; Q36-A38 PolarHBondContact O-N 2.86Å; Q36-L39 PolarHBondContact O-N 3.22Å; Q36-L40 WeakPolarHBondContact O-CG 3.49Å; Q36-L40 PolarHBondContact O-N 3.17Å; Q36-H83 PolarHBondContact NE2-O 2.94Å; Q36-D84 PolarHBondContact NE2-O 3.24Å; Q36-L85 HydrophobicContact CB-CD2 3.6Å; Q36-L85 HydrophobicContact CG-CD2 3.72Å; Q36-L85 HydrophobicContact CG-CG 4.19Å
37L82.6Confident81.6Confident4 Ų463.9 Ų63.92%0.02132%0.324CS..Hα-helixtrans-61-40.8174-164.174.3000112P31 N33 E34 L35 L40 K41 V57 G59 V60P31-L37 HydrophobicContact CB-CB 4.36Å; P31-L37 HydrophobicContact CB-CD1 4.15Å; P31-L37 HydrophobicContact CG-CD1 3.51Å; N33-L37 PolarHBondContact O-N 3.22Å; E34-L37 WeakPolarHBondContact O-CB 3.5Å; E34-L37 PolarHBondContact O-N 3.43Å; E34-L37 WeakPolarHBondContact OE2-CD2 3.46Å; L35-L37 VanDerWaalsContact C-N 3.32Å; L35-L37 PolarHBondContact O-N 3.5Å; L37-L40 PolarHBondContact O-N 2.67Å; L37-K41 WeakPolarHBondContact O-CG 3.48Å; L37-K41 PolarHBondContact O-N 2.8Å; L37-V57 HydrophobicContact CD1-CG1 3.05Å; L37-V57 HydrophobicContact CD2-CG1 4.41Å; L37-V57 HydrophobicContact CG-CG1 3.56Å; L37-G59 VanDerWaalsContact CD1-C 3.46Å; L37-G59 VanDerWaalsContact CD1-O 3.31Å; L37-G59 WeakPolarHBondContact CD1-O 3.09Å; L37-V60 HydrophobicContact CB-CG2 4.38Å; L37-V60 HydrophobicContact CD2-CG2 4.13Å
38A84.1Confident81.2Confident59 Ų5970 Ų7049%0.48835%0.352SS..Hα-helixtrans-67.4-37.6178.600000112.3E34 L35 Q36 L40 K41 N42E34-A38 WeakPolarHBondContact O-CB 3.37Å; E34-A38 PolarHBondContact O-N 3.03Å; L35-A38 PolarHBondContact O-N 2.86Å; Q36-A38 VanDerWaalsContact C-N 3.31Å; Q36-A38 PolarHBondContact O-N 2.86Å; A38-L40 VanDerWaalsContact C-N 3.34Å; A38-L40 PolarHBondContact O-N 3.32Å; A38-K41 PolarHBondContact O-N 3.33Å; A38-K41 VanDerWaalsContact O-N 3.14Å; A38-N42 PolarHBondContact O-N 3.02Å
39L84.4Confident81Confident38 Ų3867.2 Ų67.220%0.19934%0.342CS..Hα-helixtrans-61.1-42.1174.6-68.3171.2000111.8L35 Q36 K41 N42 H83L35-L39 HydrophobicContact CD2-CD1 4.24Å; L35-L39 WeakPolarHBondContact O-CG 3.3Å; L35-L39 PolarHBondContact O-N 2.93Å; L35-L39 VanDerWaalsContact O-N 3.09Å; Q36-L39 PolarHBondContact O-N 3.22Å; L39-K41 PolarHBondContact O-N 2.93Å; L39-N42 WeakPolarHBondContact O-CB 3.29Å; L39-N42 PolarHBondContact O-N 3.1Å; L39-H83 HydrophobicContact CD1-CB 3.84Å
40L78.6Confident80.8Confident21 Ų2172.5 Ų72.511%0.1137%0.367CS..Hα-helixtrans-72.8-13177.2-62.9175.9000113.8I29 P31 Q36 L37 A38 V57 V64 L80 L85I29-L40 HydrophobicContact CB-CD1 4.33Å; I29-L40 HydrophobicContact CD1-CD2 3.94Å; I29-L40 HydrophobicContact CG2-CD1 3.77Å; I29-L40 HydrophobicContact CG2-CD2 4.13Å; P31-L40 HydrophobicContact CB-CD1 4.05Å; P31-L40 HydrophobicContact CG-CD1 4.1Å; Q36-L40 WeakPolarHBondContact O-CG 3.49Å; Q36-L40 PolarHBondContact O-N 3.17Å; L37-L40 PolarHBondContact O-N 2.67Å; A38-L40 VanDerWaalsContact C-N 3.34Å; A38-L40 PolarHBondContact O-N 3.32Å; L40-V57 HydrophobicContact CB-CG2 4.15Å; L40-V64 HydrophobicContact CD1-CB 4.35Å; L40-V64 HydrophobicContact CD1-CG2 3.98Å; L40-L80 HydrophobicContact CD2-CD2 4.31Å; L40-L85 HydrophobicContact CD1-CD2 4.14Å; L40-L85 HydrophobicContact CD2-CD1 4.1Å; L40-L85 HydrophobicContact CG-CD1 4.42Å; L40-L85 HydrophobicContact CG-CD2 4.31Å
41K74.6Confident80.7Confident110 Ų11071 Ų7148%0.47836%0.356SS..THydrogen-bonded Turntrans-93.1-6.6173.9-73.5177.3-179.5178.20113L37 A38 L39 Q43 V57L37-K41 WeakPolarHBondContact O-CG 3.48Å; L37-K41 PolarHBondContact O-N 2.8Å; A38-K41 PolarHBondContact O-N 3.33Å; A38-K41 VanDerWaalsContact O-N 3.14Å; L39-K41 PolarHBondContact O-N 2.93Å; K41-Q43 PolarHBondContact O-N 2.52Å; K41-V57 HydrophobicContact CD-CG1 4.25Å; K41-V57 VanDerWaalsContact CE-CG1 3.41Å; K41-V57 HydrophobicContact CG-CB 3.89Å; K41-V57 HydrophobicContact CG-CG1 3.89Å; K41-V57 HydrophobicContact CG-CG2 4.01Å
42N79.4Confident80.6Confident54 Ų5473.2 Ų73.229%0.28937%0.368SS..  trans-71118.1-174.9-170.7-7.8000110.8A38 L39 E44 E45 I46A38-N42 PolarHBondContact O-N 3.02Å; L39-N42 WeakPolarHBondContact O-CB 3.29Å; L39-N42 PolarHBondContact O-N 3.1Å; N42-E44 VanDerWaalsContact C-N 3.32Å; N42-E44 PolarHBondContact O-N 3.12Å; N42-E44 PolarHBondContact OD1-N 3.44Å; N42-E45 HydrophobicContact CB-CB 4.3Å; N42-E45 HydrophobicContact CB-CG 3.77Å; N42-E45 PolarHBondContact O-N 2.68Å; N42-I46 WeakPolarHBondContact O-CG1 3.4Å; N42-I46 PolarHBondContact O-N 2.71Å
43Q57.6Low80.3Confident155 Ų15571 Ų7172%0.72436%0.363SS*.Hα-helixtrans-69.6-29.1-178.8-71-171-21.100112.9K41 E45 I46 V47K41-Q43 PolarHBondContact O-N 2.52Å; Q43-E45 VanDerWaalsContact C-N 3.32Å; Q43-I46 PolarHBondContact O-N 3.01Å; Q43-V47 VanDerWaalsContact O-CG2 3.29Å; Q43-V47 WeakPolarHBondContact O-CG2 3.3Å; Q43-V47 PolarHBondContact O-N 3.34Å; Q43-V47 VanDerWaalsContact O-N 3.07Å
44E61.5Low79.8Confident148 Ų14872.8 Ų72.869%0.69236%0.364SS*.Hα-helixtrans-64.6-41.1177.4-67-179.1168.500110.4N42 V47 E48N42-E44 VanDerWaalsContact C-N 3.32Å; N42-E44 PolarHBondContact O-N 3.12Å; N42-E44 PolarHBondContact OD1-N 3.44Å; E44-V47 PolarHBondContact O-N 2.79Å; E44-E48 VanDerWaalsContact O-CB 3.31Å; E44-E48 WeakPolarHBondContact O-CB 3.38Å; E44-E48 PolarHBondContact O-N 3.19Å
45E72.8Confident79.4Confident37 Ų3770.3 Ų70.317%0.17335%0.354CS..Hα-helixtrans-69.3-38.5177.4-55.7-64.5161.400112.3N42 Q43 V47 E48 F49N42-E45 HydrophobicContact CB-CB 4.3Å; N42-E45 HydrophobicContact CB-CG 3.77Å; N42-E45 PolarHBondContact O-N 2.68Å; Q43-E45 VanDerWaalsContact C-N 3.32Å; E45-V47 VanDerWaalsContact C-N 3.26Å; E45-V47 PolarHBondContact O-N 3.23Å; E45-E48 PolarHBondContact O-N 3.11Å; E45-F49 HydrophobicContact CB-CD2 4.41Å; E45-F49 VanDerWaalsContact O-CD2 3.28Å; E45-F49 WeakPolarHBondContact O-CD2 3.39Å; E45-F49 PolarHBondContact O-N 2.86Å; E45-F49 WeakPolarHBondContact OE2-CE2 3.24Å
46I71.3Confident78.5Confident48 Ų4866.1 Ų66.125%0.24634%0.341CS..Hα-helixtrans-61.8-39175.4-69.1168.7000110.4N42 Q43 E50 L51 V53N42-I46 WeakPolarHBondContact O-CG1 3.4Å; N42-I46 PolarHBondContact O-N 2.71Å; Q43-I46 PolarHBondContact O-N 3.01Å; I46-E50 WeakPolarHBondContact O-CA 3.25Å; I46-E50 PolarHBondContact O-N 3.07Å; I46-L51 HydrophobicContact CG1-CD1 4.45Å; I46-L51 HydrophobicContact CG2-CB 4.36Å; I46-L51 PolarHBondContact O-N 2.75Å; I46-V53 HydrophobicContact CD1-CG2 4.41Å
47V75.5Confident77.7Confident112 Ų11267.5 Ų67.568%0.67935%0.349SS*.Hα-helixtrans-75.3-41.9177.3173.40000111.2Q43 E44 E45 E50Q43-V47 VanDerWaalsContact O-CG2 3.29Å; Q43-V47 WeakPolarHBondContact O-CG2 3.3Å; Q43-V47 PolarHBondContact O-N 3.34Å; Q43-V47 VanDerWaalsContact O-N 3.07Å; E44-V47 PolarHBondContact O-N 2.79Å; E45-V47 VanDerWaalsContact C-N 3.26Å; E45-V47 PolarHBondContact O-N 3.23Å; V47-E50 PolarHBondContact O-N 3.31Å
48E83.9Confident77Confident128 Ų12872.4 Ų72.460%0.59838%0.38SS*.Hα-helixtrans-62.8-44.1-178.9179.8169.9176.200112.5E44 E45E44-E48 VanDerWaalsContact O-CB 3.31Å; E44-E48 WeakPolarHBondContact O-CB 3.38Å; E44-E48 PolarHBondContact O-N 3.19Å; E45-E48 PolarHBondContact O-N 3.11Å
49F86Confident76.5Confident15 Ų1570.3 Ų70.37%0.06636%0.364CS..THydrogen-bonded Turntrans-92.92.3-179.4-62.6-64.7000113.9E45 L51 T72 F76 Y79E45-F49 HydrophobicContact CB-CD2 4.41Å; E45-F49 VanDerWaalsContact O-CD2 3.28Å; E45-F49 WeakPolarHBondContact O-CD2 3.39Å; E45-F49 PolarHBondContact O-N 2.86Å; E45-F49 WeakPolarHBondContact OE2-CE2 3.24Å; F49-L51 VanDerWaalsContact C-N 3.28Å; F49-L51 HydrophobicContact CB-CD1 4.34Å; F49-L51 HydrophobicContact CB-CD2 3.67Å; F49-L51 HydrophobicContact CB-CG 3.76Å; F49-L51 PolarHBondContact O-N 3.28Å; F49-T72 PolarHBondContact O-OG1 3.36Å; F49-F76 HydrophobicContact CB-CB 4.46Å; F49-F76 HydrophobicContact CB-CD2 4.07Å; F49-F76 HydrophobicContact CB-CG 4.45Å; F49-F76 HydrophobicContact CD1-CB 3.92Å; F49-F76 HydrophobicContact CD1-CD2 4.22Å; F49-F76 AromaticContact CD2-CD2 3.51Å; F49-F76 HydrophobicContact CD2-CD2 3.51Å; F49-F76 HydrophobicContact CD2-CE2 4.09Å; F49-F76 HydrophobicContact CE1-CB 4.34Å; F49-F76 AromaticContact CE2-CD2 3.92Å; F49-F76 HydrophobicContact CE2-CD2 3.92Å; F49-F76 HydrophobicContact CG-CB 4.12Å; F49-F76 AromaticContact CG-CD2 3.67Å; F49-F76 HydrophobicContact CG-CD2 3.67Å; F49-F76 HydrophobicContact CG-CG 4.26Å; F49-F76 HydrophobicContact CZ-CD2 4.46Å; F49-Y79 HydrophobicContact CE2-CD1 4.11Å; F49-Y79 HydrophobicContact CE2-CD2 4.12Å; F49-Y79 AromaticContact CE2-CG 3.86Å; F49-Y79 HydrophobicContact CE2-CG 3.86Å; F49-Y79 HydrophobicContact CZ-CD2 4.21Å; F49-Y79 AromaticContact CZ-CG 3.96Å; F49-Y79 HydrophobicContact CZ-CG 3.96Å
50E87Confident76.5Confident111 Ų11170.3 Ų70.352%0.51937%0.365SS..THydrogen-bonded Turntrans53.643.3-177.2-59.4-175.4-179.600112.8I46 V47 P69 H71I46-E50 WeakPolarHBondContact O-CA 3.25Å; I46-E50 PolarHBondContact O-N 3.07Å; V47-E50 PolarHBondContact O-N 3.31Å; E50-P69 HydrophobicContact CB-CG 3.99Å; E50-P69 WeakPolarHBondContact O-CD 3.4Å; E50-H71 IonicContact OE1-NE2 3.76Å; E50-H71 IonicContact OE2-CE1 2.9Å; E50-H71 PolarHBondContact OE2-CE1 3.45Å; E50-H71 VanDerWaalsContact OE2-CE1 3.26Å; E50-H71 IonicContact OE2-NE2 3.76Å; E50-H71 PolarHBondContact OE2-NE2 3.33Å
51L85.5Confident76.6Confident23 Ų2373.2 Ų73.212%0.1239%0.388CS..  trans-74.5135.6-175-54.6178.9000111.5I46 F49 V68 F76I46-L51 HydrophobicContact CG1-CD1 4.45Å; I46-L51 HydrophobicContact CG2-CB 4.36Å; I46-L51 PolarHBondContact O-N 2.75Å; F49-L51 VanDerWaalsContact C-N 3.28Å; F49-L51 HydrophobicContact CB-CD1 4.34Å; F49-L51 HydrophobicContact CB-CD2 3.67Å; F49-L51 HydrophobicContact CB-CG 3.76Å; F49-L51 PolarHBondContact O-N 3.28Å; L51-V68 HydrophobicContact CD2-CB 4.37Å; L51-V68 HydrophobicContact CD2-CG1 4Å; L51-V68 HydrophobicContact CD2-CG2 3.94Å; L51-F76 HydrophobicContact CD1-CD2 4.25Å; L51-F76 HydrophobicContact CD1-CE1 4.37Å; L51-F76 HydrophobicContact CD1-CE2 3.53Å; L51-F76 HydrophobicContact CD1-CZ 3.59Å; L51-F76 HydrophobicContact CD2-CD1 4.05Å; L51-F76 HydrophobicContact CD2-CD2 4.16Å; L51-F76 HydrophobicContact CD2-CE1 3.95Å; L51-F76 HydrophobicContact CD2-CE2 4.1Å; L51-F76 HydrophobicContact CD2-CG 4.13Å; L51-F76 HydrophobicContact CD2-CZ 3.97Å; L51-F76 HydrophobicContact CG-CE2 4.41Å; L51-F76 HydrophobicContact CG-CZ 4.46Å
52D85.5Confident76.8Confident47 Ų4774.9 Ų74.925%0.25139%0.392SS..EExtended strand (participates in β ladder)trans-108.2106.7169.7167.628.1000109.7W54 V66 R67D52-W54 VanDerWaalsContact O-CD1 3.24Å; D52-W54 PolarHBondContact O-N 3.25Å; D52-W54 PolarHBondContact OD2-NE1 3.23Å; D52-V66 WeakPolarHBondContact O-CA 3.31Å; D52-R67 HydrophobicContact CB-CB 4.14Å; D52-R67 PolarHBondContact N-O 3.27Å; D52-R67 PolarHBondContact O-N 2.54Å; D52-R67 IonicContact OD2-CZ 3.65Å; D52-R67 IonicContact OD2-NE 2.7Å; D52-R67 PolarHBondContact OD2-NE 3.47Å; D52-R67 IonicContact OD2-NH2 3.48Å; D52-R67 PolarHBondContact OD2-NH2 3.47Å; D52-R67 VanDerWaalsContact OD2-NH2 3.12Å
53V84.3Confident77.1Confident46 Ų4674 Ų7428%0.27939%0.389SS..EExtended strand (participates in β ladder)trans-80.3113.4-174.1-174.30000110.1I46 M55 V66 R184I46-V53 HydrophobicContact CD1-CG2 4.41Å; V53-M55 WeakPolarHBondContact CG1-O 3.1Å; V53-V66 HydrophobicContact CG1-CG1 4.45Å; V53-V66 HydrophobicContact CG2-CG1 4.1Å; V53-R184 PolarHBondContact O-NH1 3.13Å
54W79.1Confident78.4Confident108 Ų10866.8 Ų66.841%0.40936%0.356SS..EExtended strand (participates in β ladder)trans-89-42.6-179.9-73.219.6000111.3V26 D52 D65 R67 I91V26-W54 HydrophobicContact CG1-CE3 4.12Å; V26-W54 HydrophobicContact CG1-CZ3 4.45Å; V26-W54 HydrophobicContact CG2-CD2 4.33Å; V26-W54 HydrophobicContact CG2-CE3 4.03Å; V26-W54 HydrophobicContact CG2-CH2 3.67Å; V26-W54 HydrophobicContact CG2-CZ2 3.98Å; V26-W54 HydrophobicContact CG2-CZ3 3.7Å; D52-W54 VanDerWaalsContact O-CD1 3.24Å; D52-W54 PolarHBondContact O-N 3.25Å; D52-W54 PolarHBondContact OD2-NE1 3.23Å; W54-D65 HydrophobicContact CB-CB 4.23Å; W54-D65 PolarHBondContact N-O 2.93Å; W54-R67 HydrophobicContact CZ2-CB 4.2Å; W54-I91 HydrophobicContact CH2-CD1 4.18Å; W54-I91 HydrophobicContact CZ3-CD1 3.87Å
55M76.6Confident79.7Confident80 Ų8060.5 Ų60.539%0.39433%0.327SS..EExtended strand (participates in β ladder)trans-122.1113.2172-170.1176.7-58.700109.2V53 P63 V64 D65V53-M55 WeakPolarHBondContact CG1-O 3.1Å; M55-P63 HydrophobicContact SD-CG 4.03Å; M55-V64 WeakPolarHBondContact O-CG1 3.4Å; M55-D65 HydrophobicContact CB-CB 3.81Å; M55-D65 PolarHBondContact N-O 3.41Å; M55-D65 VanDerWaalsContact N-O 3.11Å; M55-D65 PolarHBondContact O-N 2.96Å
56G70.9Confident80.5Confident38 Ų3858.9 Ų58.939%0.39232%0.32SS..  trans-72165.6-175.700000113.9T58G56-T58 PolarHBondContact O-N 3.48Å; G56-T58 VanDerWaalsContact O-N 3.16Å
57V71.1Confident81.5Confident35 Ų3558.1 Ų58.121%0.21231%0.314CS..  trans-77.1100.1-174.3-1690000111.5L37 L40 K41 V64L37-V57 HydrophobicContact CD1-CG1 3.05Å; L37-V57 HydrophobicContact CD2-CG1 4.41Å; L37-V57 HydrophobicContact CG-CG1 3.56Å; L40-V57 HydrophobicContact CB-CG2 4.15Å; K41-V57 HydrophobicContact CD-CG1 4.25Å; K41-V57 VanDerWaalsContact CE-CG1 3.41Å; K41-V57 HydrophobicContact CG-CB 3.89Å; K41-V57 HydrophobicContact CG-CG1 3.89Å; K41-V57 HydrophobicContact CG-CG2 4.01Å; V57-V64 HydrophobicContact CB-CG2 4.34Å; V57-V64 HydrophobicContact CG1-CG2 4.31Å; V57-V64 HydrophobicContact CG2-CG1 4.05Å; V57-V64 HydrophobicContact CG2-CG2 3.88Å
58T68.1Low82.2Confident107 Ų10752.8 Ų52.866%0.65628%0.281SS*.  trans-95.4-24.3-175.253.10000114.3G56 Y62G56-T58 PolarHBondContact O-N 3.48Å; G56-T58 VanDerWaalsContact O-N 3.16Å; T58-Y62 WeakPolarHBondContact OG1-CB 3.3Å
59G73.3Confident82.6Confident15 Ų1546.9 Ų46.916%0.15525%0.254CS..SBendtrans169.5173.4177.700000112.6L37 Y62L37-G59 VanDerWaalsContact CD1-C 3.46Å; L37-G59 VanDerWaalsContact CD1-O 3.31Å; L37-G59 WeakPolarHBondContact CD1-O 3.09Å; G59-Y62 PolarHBondContact O-N 2.93Å
60V83.6Confident82.9Confident38 Ų3849.2 Ų49.223%0.2327%0.27CS..THydrogen-bonded Turntrans-59.9142.7172.9178.70000110K32 E34 L37 Y62K32-V60 VanDerWaalsContact C-CG1 3.42Å; K32-V60 VanDerWaalsContact O-CG1 3.31Å; K32-V60 WeakPolarHBondContact O-CG1 3.45Å; E34-V60 HydrophobicContact CG-CG2 3.99Å; E34-V60 WeakPolarHBondContact OE1-CG2 3.42Å; L37-V60 HydrophobicContact CB-CG2 4.38Å; L37-V60 HydrophobicContact CD2-CG2 4.13Å; V60-Y62 VanDerWaalsContact O-CD2 3.31Å; V60-Y62 WeakPolarHBondContact O-CD2 3.3Å; V60-Y62 PolarHBondContact O-N 3.45Å
61S80.9Confident83.2Confident83 Ų8349.8 Ų49.858%0.5827%0.273SS*.THydrogen-bonded Turntrans653.6-176.4-520000115.8P31P31-S61 WeakPolarHBondContact O-CA 3.16Å; P31-S61 PolarHBondContact O-N 3.05Å
62Y79.7Confident83.6Confident144 Ų14449.4 Ų49.457%0.56527%0.271SS*.SBendtrans-92.6136.6169.6-69.1-87.8000110.3P31 T58 G59 V60P31-Y62 VanDerWaalsContact CD-O 3.31Å; P31-Y62 WeakPolarHBondContact CD-O 2.89Å; T58-Y62 WeakPolarHBondContact OG1-CB 3.3Å; G59-Y62 PolarHBondContact O-N 2.93Å; V60-Y62 VanDerWaalsContact O-CD2 3.31Å; V60-Y62 WeakPolarHBondContact O-CD2 3.3Å; V60-Y62 PolarHBondContact O-N 3.45Å
63P85Confident83.9Confident36 Ų3647.8 Ų47.823%0.23426%0.263CS..  trans-66.5145.6-178.227.5-33.8000111.9R28 I29 V30 M55R28-P63 HydrophobicContact CG-CB 3.92Å; I29-P63 WeakPolarHBondContact O-CA 3.49Å; V30-P63 HydrophobicContact CG2-CB 4.36Å; M55-P63 HydrophobicContact SD-CG 4.03Å
64V85.4Confident84.4Confident3 Ų351.1 Ų51.12%0.01828%0.276CS..EExtended strand (participates in β ladder)trans-118.4121.6171.2-175.60000107R28 I29 L40 M55 V57 V66R28-V64 CarbonylContact C-O 3.6Å; R28-V64 WeakPolarHBondContact CA-O 3.46Å; I29-V64 PolarHBondContact N-O 3.39Å; I29-V64 PolarHBondContact O-N 2.72Å; L40-V64 HydrophobicContact CD1-CB 4.35Å; L40-V64 HydrophobicContact CD1-CG2 3.98Å; M55-V64 WeakPolarHBondContact O-CG1 3.4Å; V57-V64 HydrophobicContact CB-CG2 4.34Å; V57-V64 HydrophobicContact CG1-CG2 4.31Å; V57-V64 HydrophobicContact CG2-CG1 4.05Å; V57-V64 HydrophobicContact CG2-CG2 3.88Å; V64-V66 HydrophobicContact CG1-CG1 4.08Å
65D88.2Confident85.1Confident16 Ų1649.4 Ų49.49%0.08628%0.28CS..EExtended strand (participates in β ladder)trans-107.7123.6-179.4-64.3-20.3000108.8V26 L27 R28 W54 M55V26-D65 HydrophobicContact CG1-CB 4.44Å; L27-D65 WeakPolarHBondContact O-CA 3.34Å; R28-D65 WeakPolarHBondContact CA-OD1 3.41Å; R28-D65 VanDerWaalsContact CB-OD1 3.25Å; R28-D65 WeakPolarHBondContact CB-OD1 3.11Å; R28-D65 WeakPolarHBondContact CG-OD1 3.37Å; R28-D65 IonicContact CZ-OD1 2.72Å; R28-D65 IonicContact CZ-OD2 3.88Å; R28-D65 IonicContact NE-OD1 2.91Å; R28-D65 PolarHBondContact NE-OD1 3.28Å; R28-D65 IonicContact NE-OD2 2.96Å; R28-D65 IonicContact NH2-OD1 3.24Å; R28-D65 PolarHBondContact NH2-OD1 3.15Å; R28-D65 IonicContact NH2-OD2 3.44Å; R28-D65 PolarHBondContact NH2-OD2 3.48Å; W54-D65 HydrophobicContact CB-CB 4.23Å; W54-D65 PolarHBondContact N-O 2.93Å; M55-D65 HydrophobicContact CB-CB 3.81Å; M55-D65 PolarHBondContact N-O 3.41Å; M55-D65 VanDerWaalsContact N-O 3.11Å; M55-D65 PolarHBondContact O-N 2.96Å
66V88.9Confident85.9Confident4 Ų445.8 Ų45.82%0.02426%0.262CS..EExtended strand (participates in β ladder)trans-130.5132-177.3-62.60000111V26 L27 I29 D52 V53 V64 V68 F76V26-V66 CarbonylContact C-O 3.54Å; V26-V66 WeakPolarHBondContact CA-O 3.35Å; L27-V66 HydrophobicContact CB-CG2 4.29Å; L27-V66 PolarHBondContact N-O 3.35Å; L27-V66 PolarHBondContact O-N 3.09Å; I29-V66 HydrophobicContact CD1-CG2 3.81Å; D52-V66 WeakPolarHBondContact O-CA 3.31Å; V53-V66 HydrophobicContact CG1-CG1 4.45Å; V53-V66 HydrophobicContact CG2-CG1 4.1Å; V64-V66 HydrophobicContact CG1-CG1 4.08Å; V66-V68 HydrophobicContact CG2-CG2 4.01Å; V66-F76 HydrophobicContact CG2-CE1 3.81Å; V66-F76 HydrophobicContact CG2-CZ 4.2Å
67R92.3Very high87Confident32 Ų3245.2 Ų45.212%0.12125%0.249CC..EExtended strand (participates in β ladder)trans-82.9129.5166.3177.3-175.264.487.44.4108.9H24 Q25 V26 D52 W54 V94H24-R67 HydrophobicContact CB-CG 4.18Å; H24-R67 PolarHBondContact CE1-NH1 3.1Å; H24-R67 PolarHBondContact ND1-NH1 3.14Å; Q25-R67 CarbonylContact O-C 3.53Å; Q25-R67 WeakPolarHBondContact O-CA 3.38Å; V26-R67 HydrophobicContact CG2-CB 4.17Å; D52-R67 HydrophobicContact CB-CB 4.14Å; D52-R67 PolarHBondContact N-O 3.27Å; D52-R67 PolarHBondContact O-N 2.54Å; D52-R67 IonicContact OD2-CZ 3.65Å; D52-R67 IonicContact OD2-NE 2.7Å; D52-R67 PolarHBondContact OD2-NE 3.47Å; D52-R67 IonicContact OD2-NH2 3.48Å; D52-R67 PolarHBondContact OD2-NH2 3.47Å; D52-R67 VanDerWaalsContact OD2-NH2 3.12Å; W54-R67 HydrophobicContact CZ2-CB 4.2Å; R67-V94 HydrophobicContact CG-CG2 4.36Å
68V91.8Very high88.1Confident0 Ų047 Ų470%026%0.262CS..EExtended strand (participates in β ladder)trans-120.6126.1-176-165.10000109.4H24 Q25 L27 L51 V66 L73 F76H24-V68 WeakPolarHBondContact CA-O 3.47Å; Q25-V68 PolarHBondContact N-O 2.64Å; Q25-V68 VanDerWaalsContact N-O 3.14Å; Q25-V68 PolarHBondContact O-N 2.67Å; L27-V68 HydrophobicContact CD1-CG2 4.04Å; L27-V68 HydrophobicContact CG-CG2 4.08Å; L51-V68 HydrophobicContact CD2-CB 4.37Å; L51-V68 HydrophobicContact CD2-CG1 4Å; L51-V68 HydrophobicContact CD2-CG2 3.94Å; V66-V68 HydrophobicContact CG2-CG2 4.01Å; V68-L73 HydrophobicContact CB-CD1 3.95Å; V68-L73 HydrophobicContact CG1-CB 4.37Å; V68-L73 HydrophobicContact CG1-CD1 4.09Å; V68-F76 HydrophobicContact CB-CD1 4.46Å; V68-F76 HydrophobicContact CG1-CB 4.09Å; V68-F76 HydrophobicContact CG1-CD1 3.93Å; V68-F76 HydrophobicContact CG1-CG 4.28Å; V68-F76 HydrophobicContact CG2-CD1 3.66Å; V68-F76 HydrophobicContact CG2-CE1 3.84Å
69P91.6Very high89.3Confident4 Ų443.1 Ų43.13%0.02624%0.236CC..  trans-62.1148.1173.4-24.235000113.8H24 E50 H71 T72 L73H24-P69 WeakPolarHBondContact ND1-CA 3.46Å; E50-P69 HydrophobicContact CB-CG 3.99Å; E50-P69 WeakPolarHBondContact O-CD 3.4Å; P69-H71 VanDerWaalsContact CB-CE1 3.42Å; P69-H71 WeakPolarHBondContact CB-CE1 3.33Å; P69-H71 WeakPolarHBondContact CB-ND1 3.48Å; P69-H71 PolarHBondContact O-N 3.13Å; P69-H71 VanDerWaalsContact O-N 3.15Å; P69-T72 WeakPolarHBondContact CD-OG1 3.4Å; P69-T72 PolarHBondContact O-N 3.13Å; P69-T72 VanDerWaalsContact O-N 3.15Å; P69-T72 PolarHBondContact O-OG1 2.87Å; P69-L73 WeakPolarHBondContact O-CB 3.37Å; P69-L73 PolarHBondContact O-N 2.85Å
70P92.8Very high90.2Very high63 Ų6342.4 Ų42.441%0.40923%0.229SC..THydrogen-bonded Turntrans-60.4-30.1-177.223.7-35.1000113.1H24H24-P70 WeakPolarHBondContact CD2-CD 3.38Å; H24-P70 WeakPolarHBondContact NE2-CD 3.38Å
71H92.2Very high90.6Very high124 Ų12445.6 Ų45.657%0.57424%0.244SC*.THydrogen-bonded Turntrans-78.3-20.5-177.370-87.1000113.5E50 P69E50-H71 IonicContact OE1-NE2 3.76Å; E50-H71 IonicContact OE2-CE1 2.9Å; E50-H71 PolarHBondContact OE2-CE1 3.45Å; E50-H71 VanDerWaalsContact OE2-CE1 3.26Å; E50-H71 IonicContact OE2-NE2 3.76Å; E50-H71 PolarHBondContact OE2-NE2 3.33Å; P69-H71 VanDerWaalsContact CB-CE1 3.42Å; P69-H71 WeakPolarHBondContact CB-CE1 3.33Å; P69-H71 WeakPolarHBondContact CB-ND1 3.48Å; P69-H71 PolarHBondContact O-N 3.13Å; P69-H71 VanDerWaalsContact O-N 3.15Å
72T94.1Very high91.2Very high14 Ų1445.7 Ų45.79%0.08625%0.245CC..THydrogen-bonded Turntrans-106-11.1173.753.80000113.2F49 P69 E74 S75 F76F49-T72 PolarHBondContact O-OG1 3.36Å; P69-T72 WeakPolarHBondContact CD-OG1 3.4Å; P69-T72 PolarHBondContact O-N 3.13Å; P69-T72 VanDerWaalsContact O-N 3.15Å; P69-T72 PolarHBondContact O-OG1 2.87Å; T72-E74 PolarHBondContact O-N 2.88Å; T72-S75 PolarHBondContact O-N 3.27Å; T72-F76 WeakPolarHBondContact O-CB 3.17Å; T72-F76 PolarHBondContact O-N 2.89Å
73L92.6Very high91.7Very high13 Ų1342.3 Ų42.37%0.06823%0.234CC..Hα-helixtrans-51.9-52.1-172-178.464.2000114.3Q25 L27 V68 P69 F76 K77Q25-L73 HydrophobicContact CB-CD1 3.93Å; Q25-L73 HydrophobicContact CB-CD2 4.36Å; Q25-L73 HydrophobicContact CG-CD1 4.23Å; Q25-L73 HydrophobicContact CG-CD2 3.75Å; L27-L73 HydrophobicContact CD1-CD1 4.32Å; V68-L73 HydrophobicContact CB-CD1 3.95Å; V68-L73 HydrophobicContact CG1-CB 4.37Å; V68-L73 HydrophobicContact CG1-CD1 4.09Å; P69-L73 WeakPolarHBondContact O-CB 3.37Å; P69-L73 PolarHBondContact O-N 2.85Å; L73-F76 PolarHBondContact O-N 3.36Å; L73-K77 HydrophobicContact CG-CD 4.43Å; L73-K77 WeakPolarHBondContact O-CG 3.47Å; L73-K77 PolarHBondContact O-N 3.47Å
74E94.2Very high92Very high117 Ų11745.7 Ų45.755%0.54725%0.25SS..Hα-helixtrans-72.9-34.4-176.1-65.9-57.3123.700112.3T72 F76 K77 S78T72-E74 PolarHBondContact O-N 2.88Å; E74-F76 VanDerWaalsContact C-N 3.35Å; E74-K77 IonicContact OE1-NZ 2.64Å; E74-K77 PolarHBondContact OE1-NZ 3.43Å; E74-S78 WeakPolarHBondContact O-CB 3.46Å; E74-S78 PolarHBondContact O-N 3.49Å; E74-S78 PolarHBondContact O-OG 3.4Å
75S93.3Very high92.3Very high72 Ų7245.6 Ų45.650%0.50325%0.25SS..Hα-helixtrans-65.4-40.7172.6-57.40000111.2T72 S78 Y79T72-S75 PolarHBondContact O-N 3.27Å; S75-S78 WeakPolarHBondContact O-CB 3.5Å; S75-S78 PolarHBondContact O-N 2.86Å; S75-Y79 PolarHBondContact O-N 3.26Å
76F94.1Very high92.4Very high3 Ų350.4 Ų50.41%0.01327%0.272CS..Hα-helixtrans-69.1-42.5177.8-176.4-119.4000112L27 I29 F49 L51 V66 V68 T72 L73 E74 S78 Y79 L80L27-F76 HydrophobicContact CD1-CD1 4.06Å; L27-F76 HydrophobicContact CD1-CE1 4.2Å; I29-F76 HydrophobicContact CD1-CE1 4.07Å; I29-F76 HydrophobicContact CD1-CZ 3.93Å; F49-F76 HydrophobicContact CB-CB 4.46Å; F49-F76 HydrophobicContact CB-CD2 4.07Å; F49-F76 HydrophobicContact CB-CG 4.45Å; F49-F76 HydrophobicContact CD1-CB 3.92Å; F49-F76 HydrophobicContact CD1-CD2 4.22Å; F49-F76 AromaticContact CD2-CD2 3.51Å; F49-F76 HydrophobicContact CD2-CD2 3.51Å; F49-F76 HydrophobicContact CD2-CE2 4.09Å; F49-F76 HydrophobicContact CE1-CB 4.34Å; F49-F76 AromaticContact CE2-CD2 3.92Å; F49-F76 HydrophobicContact CE2-CD2 3.92Å; F49-F76 HydrophobicContact CG-CB 4.12Å; F49-F76 AromaticContact CG-CD2 3.67Å; F49-F76 HydrophobicContact CG-CD2 3.67Å; F49-F76 HydrophobicContact CG-CG 4.26Å; F49-F76 HydrophobicContact CZ-CD2 4.46Å; L51-F76 HydrophobicContact CD1-CD2 4.25Å; L51-F76 HydrophobicContact CD1-CE1 4.37Å; L51-F76 HydrophobicContact CD1-CE2 3.53Å; L51-F76 HydrophobicContact CD1-CZ 3.59Å; L51-F76 HydrophobicContact CD2-CD1 4.05Å; L51-F76 HydrophobicContact CD2-CD2 4.16Å; L51-F76 HydrophobicContact CD2-CE1 3.95Å; L51-F76 HydrophobicContact CD2-CE2 4.1Å; L51-F76 HydrophobicContact CD2-CG 4.13Å; L51-F76 HydrophobicContact CD2-CZ 3.97Å; L51-F76 HydrophobicContact CG-CE2 4.41Å; L51-F76 HydrophobicContact CG-CZ 4.46Å; V66-F76 HydrophobicContact CG2-CE1 3.81Å; V66-F76 HydrophobicContact CG2-CZ 4.2Å; V68-F76 HydrophobicContact CB-CD1 4.46Å; V68-F76 HydrophobicContact CG1-CB 4.09Å; V68-F76 HydrophobicContact CG1-CD1 3.93Å; V68-F76 HydrophobicContact CG1-CG 4.28Å; V68-F76 HydrophobicContact CG2-CD1 3.66Å; V68-F76 HydrophobicContact CG2-CE1 3.84Å; T72-F76 WeakPolarHBondContact O-CB 3.17Å; T72-F76 PolarHBondContact O-N 2.89Å; L73-F76 PolarHBondContact O-N 3.36Å; E74-F76 VanDerWaalsContact C-N 3.35Å; F76-S78 VanDerWaalsContact C-N 3.31Å; F76-S78 PolarHBondContact O-N 3.05Å; F76-Y79 HydrophobicContact CD2-CD1 4.19Å; F76-Y79 HydrophobicContact CE2-CD1 4.12Å; F76-Y79 WeakPolarHBondContact O-CB 3.46Å; F76-Y79 PolarHBondContact O-N 3.49Å; F76-Y79 VanDerWaalsContact O-N 3.13Å; F76-L80 HydrophobicContact CD1-CD1 4.1Å; F76-L80 HydrophobicContact CD1-CG 4.48Å; F76-L80 HydrophobicContact CE1-CD1 3.75Å; F76-L80 HydrophobicContact CE1-CD2 4.38Å; F76-L80 HydrophobicContact CE1-CG 4.2Å; F76-L80 HydrophobicContact CE2-CD2 4.13Å; F76-L80 HydrophobicContact CE2-CG 4.34Å; F76-L80 HydrophobicContact CZ-CD1 4.1Å; F76-L80 HydrophobicContact CZ-CD2 3.88Å; F76-L80 HydrophobicContact CZ-CG 4.12Å; F76-L80 WeakPolarHBondContact O-CG 3.36Å; F76-L80 PolarHBondContact O-N 2.83Å
77K93.8Very high92.5Very high27 Ų2753.7 Ų53.712%0.11728%0.284CS..Hα-helixtrans-57.7-44.9171.8-74.1175.9-176.5163.80111.7L27 L73 E74 Y79 L80 D81 Y87L27-K77 HydrophobicContact CD1-CG 4.23Å; L73-K77 HydrophobicContact CG-CD 4.43Å; L73-K77 WeakPolarHBondContact O-CG 3.47Å; L73-K77 PolarHBondContact O-N 3.47Å; E74-K77 IonicContact OE1-NZ 2.64Å; E74-K77 PolarHBondContact OE1-NZ 3.43Å; K77-Y79 VanDerWaalsContact C-N 3.29Å; K77-Y79 PolarHBondContact O-N 3.29Å; K77-L80 WeakPolarHBondContact O-CB 3.42Å; K77-L80 PolarHBondContact O-N 3.03Å; K77-L80 VanDerWaalsContact O-N 3.15Å; K77-D81 VanDerWaalsContact O-CG 3.31Å; K77-D81 PolarHBondContact O-N 3.23Å; K77-Y87 HydrophobicContact CB-CE1 4.41Å; K77-Y87 WeakPolarHBondContact CB-OH 3.29Å; K77-Y87 HydrophobicContact CD-CE2 4.22Å; K77-Y87 HydrophobicContact CG-CE1 4.41Å; K77-Y87 HydrophobicContact CG-CE2 3.9Å; K77-Y87 WeakPolarHBondContact CG-OH 3.33Å
78S93.7Very high92.6Very high71 Ų7155 Ų5550%0.49730%0.298SS..Hα-helixtrans-61.6-38.2175.6-57.90000112.2E74 S75 F76 S82E74-S78 WeakPolarHBondContact O-CB 3.46Å; E74-S78 PolarHBondContact O-N 3.49Å; E74-S78 PolarHBondContact O-OG 3.4Å; S75-S78 WeakPolarHBondContact O-CB 3.5Å; S75-S78 PolarHBondContact O-N 2.86Å; F76-S78 VanDerWaalsContact C-N 3.31Å; F76-S78 PolarHBondContact O-N 3.05Å; S78-S82 WeakPolarHBondContact O-CB 3.46Å; S78-S82 PolarHBondContact O-N 3.41Å; S78-S82 PolarHBondContact O-OG 3.12Å
79Y93.1Very high92.6Very high27 Ų2757.8 Ų57.811%0.10632%0.315CS..Hα-helixtrans-62.7-46.1173.2170.2-93.1000111.5F49 S75 F76 K77 S82 H83F49-Y79 HydrophobicContact CE2-CD1 4.11Å; F49-Y79 HydrophobicContact CE2-CD2 4.12Å; F49-Y79 AromaticContact CE2-CG 3.86Å; F49-Y79 HydrophobicContact CE2-CG 3.86Å; F49-Y79 HydrophobicContact CZ-CD2 4.21Å; F49-Y79 AromaticContact CZ-CG 3.96Å; F49-Y79 HydrophobicContact CZ-CG 3.96Å; S75-Y79 PolarHBondContact O-N 3.26Å; F76-Y79 HydrophobicContact CD2-CD1 4.19Å; F76-Y79 HydrophobicContact CE2-CD1 4.12Å; F76-Y79 WeakPolarHBondContact O-CB 3.46Å; F76-Y79 PolarHBondContact O-N 3.49Å; F76-Y79 VanDerWaalsContact O-N 3.13Å; K77-Y79 VanDerWaalsContact C-N 3.29Å; K77-Y79 PolarHBondContact O-N 3.29Å; Y79-S82 PolarHBondContact O-N 3.27Å; Y79-S82 PolarHBondContact O-OG 3.5Å; Y79-H83 AromaticContact CD2-CE1 3.61Å; Y79-H83 AromaticContact CD2-ND1 3.7Å; Y79-H83 AromaticContact CE2-CE1 3.31Å; Y79-H83 WeakPolarHBondContact CE2-CE1 3.45Å; Y79-H83 AromaticContact CE2-ND1 3.59Å; Y79-H83 AromaticContact CZ-CE1 3.96Å; Y79-H83 AromaticContact CZ-ND1 3.93Å; Y79-H83 PolarHBondContact O-N 3.22Å; Y79-H83 PolarHBondContact O-ND1 3.01Å
80L92.8Very high92.6Very high0 Ų061.9 Ų61.90%034%0.335CS..Hα-helixtrans-60.3-47.2176.1-64.2176.6000111.4L27 I29 L40 F76 K77 S82 H83 D84 L85 Y87L27-L80 HydrophobicContact CD1-CD1 4.28Å; I29-L80 HydrophobicContact CD1-CD1 3.89Å; I29-L80 HydrophobicContact CD1-CD2 3.85Å; I29-L80 HydrophobicContact CG1-CD1 4.06Å; I29-L80 HydrophobicContact CG1-CD2 4.45Å; I29-L80 HydrophobicContact CG2-CD2 4.43Å; L40-L80 HydrophobicContact CD2-CD2 4.31Å; F76-L80 HydrophobicContact CD1-CD1 4.1Å; F76-L80 HydrophobicContact CD1-CG 4.48Å; F76-L80 HydrophobicContact CE1-CD1 3.75Å; F76-L80 HydrophobicContact CE1-CD2 4.38Å; F76-L80 HydrophobicContact CE1-CG 4.2Å; F76-L80 HydrophobicContact CE2-CD2 4.13Å; F76-L80 HydrophobicContact CE2-CG 4.34Å; F76-L80 HydrophobicContact CZ-CD1 4.1Å; F76-L80 HydrophobicContact CZ-CD2 3.88Å; F76-L80 HydrophobicContact CZ-CG 4.12Å; F76-L80 WeakPolarHBondContact O-CG 3.36Å; F76-L80 PolarHBondContact O-N 2.83Å; K77-L80 WeakPolarHBondContact O-CB 3.42Å; K77-L80 PolarHBondContact O-N 3.03Å; K77-L80 VanDerWaalsContact O-N 3.15Å; L80-S82 VanDerWaalsContact C-N 3.33Å; L80-S82 PolarHBondContact O-N 3.04Å; L80-H83 CarbonylContact O-C 3.54Å; L80-H83 PolarHBondContact O-N 3.36Å; L80-H83 VanDerWaalsContact O-N 3.13Å; L80-D84 PolarHBondContact O-N 2.89Å; L80-L85 HydrophobicContact CB-CB 4.04Å; L80-L85 HydrophobicContact CD2-CB 3.86Å; L80-L85 HydrophobicContact CD2-CD1 3.65Å; L80-L85 HydrophobicContact CD2-CG 4.38Å; L80-L85 PolarHBondContact O-N 3.38Å; L80-Y87 HydrophobicContact CB-CD1 3.84Å; L80-Y87 HydrophobicContact CB-CE1 4.1Å; L80-Y87 HydrophobicContact CD1-CD1 3.55Å; L80-Y87 HydrophobicContact CD1-CE1 4.17Å; L80-Y87 HydrophobicContact CD1-CG 3.8Å; L80-Y87 HydrophobicContact CG-CD1 4.35Å
81D93.1Very high92.4Very high104 Ų10460.9 Ų60.956%0.55633%0.326SS*.Hα-helixtrans-60-42.7177.9-70.5-25.1000111.7K77 H83 D84K77-D81 VanDerWaalsContact O-CG 3.31Å; K77-D81 PolarHBondContact O-N 3.23Å; D81-H83 PolarHBondContact O-N 2.89Å; D81-D84 PolarHBondContact O-N 2.72Å
82S92.9Very high92.4Very high86 Ų8662.3 Ų62.360%0.60133%0.333SS*.Hα-helixtrans-65.6-19.1179.571.60000114S78 Y79 L80S78-S82 WeakPolarHBondContact O-CB 3.46Å; S78-S82 PolarHBondContact O-N 3.41Å; S78-S82 PolarHBondContact O-OG 3.12Å; Y79-S82 PolarHBondContact O-N 3.27Å; Y79-S82 PolarHBondContact O-OG 3.5Å; L80-S82 VanDerWaalsContact C-N 3.33Å; L80-S82 PolarHBondContact O-N 3.04Å
83H90.7Very high92.1Very high72 Ų7264.3 Ų64.333%0.33334%0.343SS..THydrogen-bonded Turntrans-11012.6179-66.192.2000113.3Q36 L39 Y79 L80 D81 L85Q36-H83 PolarHBondContact NE2-O 2.94Å; L39-H83 HydrophobicContact CD1-CB 3.84Å; Y79-H83 AromaticContact CD2-CE1 3.61Å; Y79-H83 AromaticContact CD2-ND1 3.7Å; Y79-H83 AromaticContact CE2-CE1 3.31Å; Y79-H83 WeakPolarHBondContact CE2-CE1 3.45Å; Y79-H83 AromaticContact CE2-ND1 3.59Å; Y79-H83 AromaticContact CZ-CE1 3.96Å; Y79-H83 AromaticContact CZ-ND1 3.93Å; Y79-H83 PolarHBondContact O-N 3.22Å; Y79-H83 PolarHBondContact O-ND1 3.01Å; L80-H83 CarbonylContact O-C 3.54Å; L80-H83 PolarHBondContact O-N 3.36Å; L80-H83 VanDerWaalsContact O-N 3.13Å; D81-H83 PolarHBondContact O-N 2.89Å; H83-L85 HydrophobicContact CB-CD1 4.11Å; H83-L85 HydrophobicContact CB-CG 4.36Å; H83-L85 PolarHBondContact O-N 3.29Å
84D91.4Very high91.9Very high107 Ų10764.1 Ų64.157%0.57234%0.343SS*.THydrogen-bonded Turntrans56.131.9-179.2-167.443.3000113.1Q36 L80 D81 E86Q36-D84 PolarHBondContact NE2-O 3.24Å; L80-D84 PolarHBondContact O-N 2.89Å; D81-D84 PolarHBondContact O-N 2.72Å; D84-E86 PolarHBondContact O-N 3.4Å
85L90.7Very high91.6Very high2 Ų258.9 Ų58.91%0.0132%0.318CS..  trans-87.6102.4176.5-77.7164.4000109.3I29 Q36 L40 L80 H83I29-L85 HydrophobicContact CG2-CB 4.21Å; I29-L85 HydrophobicContact CG2-CD2 4.07Å; Q36-L85 HydrophobicContact CB-CD2 3.6Å; Q36-L85 HydrophobicContact CG-CD2 3.72Å; Q36-L85 HydrophobicContact CG-CG 4.19Å; L40-L85 HydrophobicContact CD1-CD2 4.14Å; L40-L85 HydrophobicContact CD2-CD1 4.1Å; L40-L85 HydrophobicContact CG-CD1 4.42Å; L40-L85 HydrophobicContact CG-CD2 4.31Å; L80-L85 HydrophobicContact CB-CB 4.04Å; L80-L85 HydrophobicContact CD2-CB 3.86Å; L80-L85 HydrophobicContact CD2-CD1 3.65Å; L80-L85 HydrophobicContact CD2-CG 4.38Å; L80-L85 PolarHBondContact O-N 3.38Å; H83-L85 HydrophobicContact CB-CD1 4.11Å; H83-L85 HydrophobicContact CB-CG 4.36Å; H83-L85 PolarHBondContact O-N 3.29Å
86E89.4Confident91.2Very high117 Ų11757.6 Ų57.655%0.54731%0.312SS..  trans-65.7135174.2-75.1178.4-171.300111.2V30 K32 D84V30-E86 PolarHBondContact N-O 3.03Å; K32-E86 VanDerWaalsContact CE-CD 3.43Å; K32-E86 WeakPolarHBondContact CE-OE1 3.43Å; K32-E86 WeakPolarHBondContact CE-OE2 3.26Å; K32-E86 IonicContact NZ-OE1 2.69Å; K32-E86 PolarHBondContact NZ-OE1 2.87Å; K32-E86 IonicContact NZ-OE2 3.14Å; D84-E86 PolarHBondContact O-N 3.4Å
87Y92.8Very high90.7Very high73 Ų7360.9 Ų60.929%0.28633%0.332SS..EExtended strand (participates in β ladder)trans-139.9158.8177.369.3-90.1000112.4L27 R28 K77 L80L27-Y87 HydrophobicContact CD1-CD2 4.12Å; L27-Y87 HydrophobicContact CD1-CE2 4.44Å; L27-Y87 HydrophobicContact CD2-CD2 4.27Å; R28-Y87 CarbonylContact O-C 3.59Å; R28-Y87 WeakPolarHBondContact O-CA 3.08Å; R28-Y87 WeakPolarHBondContact O-CB 3.48Å; K77-Y87 HydrophobicContact CB-CE1 4.41Å; K77-Y87 WeakPolarHBondContact CB-OH 3.29Å; K77-Y87 HydrophobicContact CD-CE2 4.22Å; K77-Y87 HydrophobicContact CG-CE1 4.41Å; K77-Y87 HydrophobicContact CG-CE2 3.9Å; K77-Y87 WeakPolarHBondContact CG-OH 3.33Å; L80-Y87 HydrophobicContact CB-CD1 3.84Å; L80-Y87 HydrophobicContact CB-CE1 4.1Å; L80-Y87 HydrophobicContact CD1-CD1 3.55Å; L80-Y87 HydrophobicContact CD1-CE1 4.17Å; L80-Y87 HydrophobicContact CD1-CG 3.8Å; L80-Y87 HydrophobicContact CG-CD1 4.35Å
88S92.9Very high90.1Very high59 Ų5961.7 Ų61.741%0.41334%0.337SS..EExtended strand (participates in β ladder)trans-133.7142.4171.661.10000110.3R28 M90R28-S88 PolarHBondContact N-O 2.87Å; R28-S88 PolarHBondContact O-N 2.8Å; S88-M90 PolarHBondContact O-N 3.21Å
89T92.8Very high89.5Confident58 Ų5861.7 Ų61.736%0.35633%0.332SS..EExtended strand (participates in β ladder)trans-76.2118.5173.5-55.10000110.2Q25 L27 I91 E92Q25-T89 HydrophobicContact CB-CG2 4.42Å; L27-T89 HydrophobicContact CD2-CG2 4.26Å; L27-T89 WeakPolarHBondContact CD2-OG1 3.21Å; T89-I91 WeakPolarHBondContact CG2-O 3.37Å; T89-E92 HydrophobicContact CG2-CG 4.06Å
90M92Very high88.8Confident91 Ų9166.5 Ų66.545%0.44836%0.357SS..EExtended strand (participates in β ladder)trans-87.8-40.6176.6-71.6-71.1-60.700111.9V26 R28 S88V26-M90 HydrophobicContact CB-CB 4.38Å; V26-M90 HydrophobicContact CG1-CB 4.28Å; V26-M90 WeakPolarHBondContact O-CB 3.46Å; V26-M90 PolarHBondContact O-N 2.6Å; R28-M90 HydrophobicContact CB-CG 3.57Å; R28-M90 HydrophobicContact CB-SD 4.13Å; S88-M90 PolarHBondContact O-N 3.21Å
91I88.6Confident87.9Confident42 Ų4268.7 Ų68.722%0.21537%0.367CS..EExtended strand (participates in β ladder)trans-132.9121.4178.9-57.4-179.9000107.5Q25 V26 W54 T89 V94 V97Q25-I91 CarbonylContact C-O 3.58Å; Q25-I91 VanDerWaalsContact CA-O 3.27Å; Q25-I91 WeakPolarHBondContact CA-O 3.36Å; V26-I91 HydrophobicContact CB-CB 3.94Å; V26-I91 HydrophobicContact CB-CD1 4.32Å; V26-I91 HydrophobicContact CB-CG1 4.14Å; V26-I91 HydrophobicContact CG2-CB 4.02Å; V26-I91 HydrophobicContact CG2-CD1 3.96Å; V26-I91 HydrophobicContact CG2-CG1 4.25Å; V26-I91 PolarHBondContact N-O 2.77Å; V26-I91 PolarHBondContact O-N 2.9Å; W54-I91 HydrophobicContact CH2-CD1 4.18Å; W54-I91 HydrophobicContact CZ3-CD1 3.87Å; T89-I91 WeakPolarHBondContact CG2-O 3.37Å; I91-V94 HydrophobicContact CG2-CG2 4.02Å; I91-V97 HydrophobicContact CG2-CG2 3.95Å
92E90.4Very high87.1Confident154 Ų15466.7 Ų66.772%0.7235%0.352SS*.SBendtrans-80.5-29.2-178-65.8-172.8168.800113.4Q25 T89Q25-E92 WeakPolarHBondContact CG-O 3.27Å; Q25-E92 PolarHBondContact NE2-O 2.85Å; T89-E92 HydrophobicContact CG2-CG 4.06Å
93D89.6Confident86.3Confident56 Ų5667.6 Ų67.630%0.29935%0.346SS..  trans-149.5107.6175.3-175.4-0.6000110.1G23 H24 Q95 A96G23-D93 PolarHBondContact N-OD1 3.39Å; G23-D93 VanDerWaalsContact N-OD1 3.15Å; H24-D93 WeakPolarHBondContact O-CA 3.46Å; D93-Q95 VanDerWaalsContact C-N 3.27Å; D93-Q95 PolarHBondContact O-N 3.44Å; D93-Q95 WeakPolarHBondContact OD1-CB 3.47Å; D93-Q95 PolarHBondContact OD1-N 2.94Å; D93-A96 HydrophobicContact CB-CB 4.02Å; D93-A96 PolarHBondContact O-N 2.83Å
94V87Confident85.2Confident9 Ų969.2 Ų69.26%0.05535%0.354CS..Hα-helixtrans-64.3-32.7178.7175.10000111.3F21 H24 V26 R67 I91 V97 L98F21-V94 HydrophobicContact CB-CB 3.99Å; F21-V94 HydrophobicContact CB-CG1 3.84Å; F21-V94 HydrophobicContact CG-CG1 4.21Å; H24-V94 HydrophobicContact CB-CB 4.13Å; H24-V94 HydrophobicContact CB-CG2 4.12Å; H24-V94 WeakPolarHBondContact O-CG2 3.26Å; H24-V94 PolarHBondContact O-N 3.36Å; V26-V94 HydrophobicContact CG2-CG2 3.75Å; R67-V94 HydrophobicContact CG-CG2 4.36Å; I91-V94 HydrophobicContact CG2-CG2 4.02Å; V94-V97 PolarHBondContact O-N 3.47Å; V94-L98 HydrophobicContact CG1-CD1 3.98Å; V94-L98 HydrophobicContact CG1-CG 4.37Å; V94-L98 WeakPolarHBondContact O-CG 3.29Å; V94-L98 PolarHBondContact O-N 3.21Å; V94-L98 VanDerWaalsContact O-N 3.14Å
95Q88.5Confident84.1Confident7 Ų765.8 Ų65.83%0.03334%0.335CS..Hα-helixtrans-67.3-39179.7-170.75851.600112F21 E22 D93 V97 L98 D99F21-Q95 HydrophobicContact CB-CB 4.47Å; F21-Q95 PolarHBondContact O-N 3.28Å; E22-Q95 HydrophobicContact CB-CB 4.45Å; E22-Q95 HydrophobicContact CG-CB 4.01Å; E22-Q95 HydrophobicContact CG-CG 3.72Å; D93-Q95 VanDerWaalsContact C-N 3.27Å; D93-Q95 PolarHBondContact O-N 3.44Å; D93-Q95 WeakPolarHBondContact OD1-CB 3.47Å; D93-Q95 PolarHBondContact OD1-N 2.94Å; Q95-V97 VanDerWaalsContact C-N 3.31Å; Q95-V97 PolarHBondContact O-N 3.15Å; Q95-L98 PolarHBondContact O-N 3.01Å; Q95-D99 VanDerWaalsContact NE2-CG 3.34Å; Q95-D99 PolarHBondContact NE2-OD1 2.56Å; Q95-D99 PolarHBondContact NE2-OD2 3.48Å; Q95-D99 WeakPolarHBondContact O-CB 3.07Å; Q95-D99 PolarHBondContact O-N 3.39Å
96A85.3Confident83.1Confident44 Ų4470.5 Ų70.536%0.36436%0.355SS..Hα-helixtrans-59.3-42177.500000112D93 D99 M100D93-A96 HydrophobicContact CB-CB 4.02Å; D93-A96 PolarHBondContact O-N 2.83Å; A96-D99 PolarHBondContact O-N 2.75Å; A96-M100 WeakPolarHBondContact O-CG 3.48Å; A96-M100 PolarHBondContact O-N 2.95Å; A96-M100 VanDerWaalsContact O-N 3.09Å
97V83.1Confident81.9Confident73 Ų7368.3 Ų68.344%0.44235%0.353SS..Hα-helixtrans-65.6-44.2176.8-177.90000111I91 V94 Q95 D99 M100 E101I91-V97 HydrophobicContact CG2-CG2 3.95Å; V94-V97 PolarHBondContact O-N 3.47Å; Q95-V97 VanDerWaalsContact C-N 3.31Å; Q95-V97 PolarHBondContact O-N 3.15Å; V97-D99 VanDerWaalsContact C-N 3.32Å; V97-D99 PolarHBondContact O-N 2.85Å; V97-M100 PolarHBondContact O-N 3.37Å; V97-E101 PolarHBondContact O-N 2.91Å; V97-E101 VanDerWaalsContact O-N 3.08Å
98L80.8Confident80.2Confident43 Ų4365.5 Ų65.523%0.22535%0.345CS..Hα-helixtrans-66.1-32.5178.1-69.1173.1000113F21 V94 Q95 R102F21-L98 HydrophobicContact CB-CD1 4.45Å; F21-L98 HydrophobicContact CD2-CD1 3.38Å; F21-L98 HydrophobicContact CE2-CD1 3.98Å; F21-L98 HydrophobicContact CG-CD1 4.22Å; V94-L98 HydrophobicContact CG1-CD1 3.98Å; V94-L98 HydrophobicContact CG1-CG 4.37Å; V94-L98 WeakPolarHBondContact O-CG 3.29Å; V94-L98 PolarHBondContact O-N 3.21Å; V94-L98 VanDerWaalsContact O-N 3.14Å; Q95-L98 PolarHBondContact O-N 3.01Å; L98-R102 WeakPolarHBondContact O-CB 3.43Å; L98-R102 VanDerWaalsContact O-CG 3.22Å; L98-R102 WeakPolarHBondContact O-CG 3.42Å; L98-R102 PolarHBondContact O-N 3.36Å
99D81.3Confident78.5Confident72 Ų7265.7 Ų65.739%0.38535%0.35SS..Hα-helixtrans-73.3-38.4177.1-73.1-20.6000111.7Q95 A96 V97 E101 R102 E103Q95-D99 VanDerWaalsContact NE2-CG 3.34Å; Q95-D99 PolarHBondContact NE2-OD1 2.56Å; Q95-D99 PolarHBondContact NE2-OD2 3.48Å; Q95-D99 WeakPolarHBondContact O-CB 3.07Å; Q95-D99 PolarHBondContact O-N 3.39Å; A96-D99 PolarHBondContact O-N 2.75Å; V97-D99 VanDerWaalsContact C-N 3.32Å; V97-D99 PolarHBondContact O-N 2.85Å; D99-E101 VanDerWaalsContact C-N 3.34Å; D99-E101 PolarHBondContact O-N 3.45Å; D99-R102 PolarHBondContact O-N 3.33Å; D99-R102 IonicContact OD1-NH1 2.69Å; D99-E103 WeakPolarHBondContact O-CG 3.17Å; D99-E103 PolarHBondContact O-N 2.98Å
100M78.3Confident76.7Confident128 Ų12872.9 Ų72.963%0.63137%0.371SS*.Hα-helixtrans-58.1-47.1170.3-71.8175.96200111.4A96 V97 E103 Q104A96-M100 WeakPolarHBondContact O-CG 3.48Å; A96-M100 PolarHBondContact O-N 2.95Å; A96-M100 VanDerWaalsContact O-N 3.09Å; V97-M100 PolarHBondContact O-N 3.37Å; M100-E103 PolarHBondContact O-N 2.95Å; M100-Q104 WeakPolarHBondContact O-CG 3.36Å; M100-Q104 PolarHBondContact O-N 3.31Å
101E74.7Confident74.9Confident45 Ų4574 Ų7421%0.2138%0.378CS..Hα-helixtrans-61.9-45.8177.8-172.2-176.5167.100111.7V97 D99 E103 Q104 M105 Y125V97-E101 PolarHBondContact O-N 2.91Å; V97-E101 VanDerWaalsContact O-N 3.08Å; D99-E101 VanDerWaalsContact C-N 3.34Å; D99-E101 PolarHBondContact O-N 3.45Å; E101-E103 PolarHBondContact O-N 3.42Å; E101-Q104 WeakPolarHBondContact O-CB 3.47Å; E101-Q104 PolarHBondContact O-N 2.94Å; E101-M105 WeakPolarHBondContact O-CG 2.91Å; E101-M105 PolarHBondContact O-N 3.26Å; E101-Y125 HydrophobicContact CG-CD2 3.92Å; E101-Y125 HydrophobicContact CG-CE2 4.18Å; E101-Y125 VanDerWaalsContact OE1-CD2 3.24Å; E101-Y125 WeakPolarHBondContact OE1-CD2 3.42Å; E101-Y125 WeakPolarHBondContact OE1-CE2 3.48Å
102R76.4Confident73.3Confident63 Ų6377.5 Ų77.524%0.23840%0.401CS..Hα-helixtrans-64.1-38178.4-76.8169.3-180173.77.9112.9K18 L98 D99 M105 K106K18-R102 VanDerWaalsContact CE-NH2 3.34Å; L98-R102 WeakPolarHBondContact O-CB 3.43Å; L98-R102 VanDerWaalsContact O-CG 3.22Å; L98-R102 WeakPolarHBondContact O-CG 3.42Å; L98-R102 PolarHBondContact O-N 3.36Å; D99-R102 PolarHBondContact O-N 3.33Å; D99-R102 IonicContact OD1-NH1 2.69Å; R102-M105 PolarHBondContact O-N 3.02Å; R102-K106 WeakPolarHBondContact O-CB 3.12Å; R102-K106 VanDerWaalsContact O-CG 3.28Å; R102-K106 WeakPolarHBondContact O-CG 3.43Å; R102-K106 PolarHBondContact O-N 3.47Å
103E75.1Confident71.9Confident105 Ų10577.3 Ų77.349%0.49140%0.4SS..Hα-helixtrans-68.6-37.7175.6-73.7-55129.200111.6D99 M100 E101 K106 S107D99-E103 WeakPolarHBondContact O-CG 3.17Å; D99-E103 PolarHBondContact O-N 2.98Å; M100-E103 PolarHBondContact O-N 2.95Å; E101-E103 PolarHBondContact O-N 3.42Å; E103-K106 PolarHBondContact O-N 3Å; E103-K106 IonicContact OE1-NZ 3.87Å; E103-K106 PolarHBondContact OE1-NZ 3.25Å; E103-S107 WeakPolarHBondContact O-CB 3.31Å; E103-S107 PolarHBondContact O-N 2.75Å; E103-S107 PolarHBondContact O-OG 3.14Å
104Q69.1Low70.5Confident105 Ų10576.4 Ų76.449%0.49140%0.397SS..Hα-helixtrans-59.5-49.8171-73.8175.2-12.400111.3M100 E101 K106 S107 A108M100-Q104 WeakPolarHBondContact O-CG 3.36Å; M100-Q104 PolarHBondContact O-N 3.31Å; E101-Q104 WeakPolarHBondContact O-CB 3.47Å; E101-Q104 PolarHBondContact O-N 2.94Å; Q104-K106 PolarHBondContact O-N 2.94Å; Q104-S107 PolarHBondContact O-N 3.47Å; Q104-S107 VanDerWaalsContact O-N 3.15Å; Q104-S107 PolarHBondContact O-OG 3.4Å; Q104-A108 PolarHBondContact O-N 2.67Å
105M66.9Low69.5Low35 Ų3584.9 Ų84.917%0.17243%0.428CS..Hα-helixtrans-59.8-43.2176.3-68.1179.683.500113.2E101 R102 S107 A108 A109 W186E101-M105 WeakPolarHBondContact O-CG 2.91Å; E101-M105 PolarHBondContact O-N 3.26Å; R102-M105 PolarHBondContact O-N 3.02Å; M105-S107 VanDerWaalsContact C-N 3.29Å; M105-S107 PolarHBondContact O-N 3.36Å; M105-A108 PolarHBondContact O-N 3.2Å; M105-A109 WeakPolarHBondContact O-CB 3.42Å; M105-A109 PolarHBondContact O-N 3.22Å; M105-W186 HydrophobicContact CE-CH2 4.29Å; M105-W186 HydrophobicContact CE-CZ3 3.61Å; M105-W186 HydrophobicContact SD-CE3 4.5Å; M105-W186 HydrophobicContact SD-CH2 4.36Å; M105-W186 HydrophobicContact SD-CZ3 3.57Å; M105-W186 VanDerWaalsContact SD-CZ3 3.57Å
106K69.3Low68.6Low101 Ų10185.6 Ų85.644%0.43943%0.433SS..Hα-helixtrans-64.3-35.7176.8-76.2176.6-165.1165.60112R102 E103 Q104 R110R102-K106 WeakPolarHBondContact O-CB 3.12Å; R102-K106 VanDerWaalsContact O-CG 3.28Å; R102-K106 WeakPolarHBondContact O-CG 3.43Å; R102-K106 PolarHBondContact O-N 3.47Å; E103-K106 PolarHBondContact O-N 3Å; E103-K106 IonicContact OE1-NZ 3.87Å; E103-K106 PolarHBondContact OE1-NZ 3.25Å; Q104-K106 PolarHBondContact O-N 2.94Å; K106-R110 WeakPolarHBondContact O-CG 3.22Å; K106-R110 PolarHBondContact O-N 3.13Å
107S64.4Low68Low71 Ų7183.7 Ų83.750%0.49742%0.416SS..Hα-helixtrans-68.4-39.8176.776.70000111.5E103 Q104 M105 R110E103-S107 WeakPolarHBondContact O-CB 3.31Å; E103-S107 PolarHBondContact O-N 2.75Å; E103-S107 PolarHBondContact O-OG 3.14Å; Q104-S107 PolarHBondContact O-N 3.47Å; Q104-S107 VanDerWaalsContact O-N 3.15Å; Q104-S107 PolarHBondContact O-OG 3.4Å; M105-S107 VanDerWaalsContact C-N 3.29Å; M105-S107 PolarHBondContact O-N 3.36Å; S107-R110 PolarHBondContact O-N 3.43Å
108A57.6Low66.7Low14 Ų1481.8 Ų81.812%0.11640%0.403CS..Hα-helixtrans-66.3-42.9174.700000111.9Q104 M105 R110 L111 N124Q104-A108 PolarHBondContact O-N 2.67Å; M105-A108 PolarHBondContact O-N 3.2Å; A108-R110 PolarHBondContact O-N 3.06Å; A108-R110 VanDerWaalsContact O-N 3.14Å; A108-L111 VanDerWaalsContact O-CB 3.27Å; A108-L111 WeakPolarHBondContact O-CB 3.46Å; A108-L111 PolarHBondContact O-N 3.18Å; A108-N124 HydrophobicContact CB-CB 3.82Å
109A57.5Low65.8Low64 Ų6482.1 Ų82.153%0.52941%0.41SS..THydrogen-bonded Turntrans-66.3-13.317800000114.5M105 L111M105-A109 WeakPolarHBondContact O-CB 3.42Å; M105-A109 PolarHBondContact O-N 3.22Å; A109-L111 VanDerWaalsContact C-N 3.32Å
110R55.3Low65.4Low209 Ų20979 Ų7979%0.78939%0.393SS*.THydrogen-bonded Turntrans-83.3-7.9172.8-74.3174.3-176.6178.94.3113.1K106 S107 A108K106-R110 WeakPolarHBondContact O-CG 3.22Å; K106-R110 PolarHBondContact O-N 3.13Å; S107-R110 PolarHBondContact O-N 3.43Å; A108-R110 PolarHBondContact O-N 3.06Å; A108-R110 VanDerWaalsContact O-N 3.14Å
111L54.2Low65.1Low115 Ų11575 Ų7560%0.60237%0.374SS*.SBendtrans-74.2157.2169.4-62.1167.5000109.8A108 A109 Q113A108-L111 VanDerWaalsContact O-CB 3.27Å; A108-L111 WeakPolarHBondContact O-CB 3.46Å; A108-L111 PolarHBondContact O-N 3.18Å; A109-L111 VanDerWaalsContact C-N 3.32Å; L111-Q113 PolarHBondContact O-N 3.45Å
112V54.8Low65Low115 Ų11574.3 Ų74.370%0.69737%0.37SS*.PPolyproline II helixtrans-55.4133179.2178.90000109.1
113Q60.8Low64.6Low150 Ų15075.5 Ų75.570%0.70139%0.393SS*.PPolyproline II helixtrans-51134.4177.2-77.8-141.8-9.200110.8L111 R115L111-Q113 PolarHBondContact O-N 3.45Å; Q113-R115 PolarHBondContact O-N 2.87Å
114P60.8Low64.4Low37 Ų3772.6 Ų72.624%0.2438%0.381CS..PPolyproline II helixtrans-60.4130.5-176.925.2-33000109.2F120 M137P114-F120 HydrophobicContact CB-CB 4.28Å; P114-F120 HydrophobicContact CB-CD2 4.02Å; P114-F120 HydrophobicContact CG-CD2 3.65Å; P114-F120 HydrophobicContact CG-CE2 4.2Å; P114-M137 HydrophobicContact CB-CE 4.14Å; P114-M137 HydrophobicContact CG-CE 4.13Å
115R66.2Low64.7Low186 Ų18671.5 Ų71.570%0.70237%0.372SS*.SBendtrans-90.6-19.5-177.7-62.7-176.2-172.31773112.4Q113 S119Q113-R115 PolarHBondContact O-N 2.87Å; R115-S119 PolarHBondContact N-OG 2.9Å
116N68.6Low65.1Low23 Ų2371.1 Ų71.112%0.12337%0.37CS..SBendtrans-154.4170.2-178.457.622.3000108.7D118 S119 F120 M137 E141N116-D118 PolarHBondContact O-N 2.83Å; N116-S119 PolarHBondContact N-OG 2.67Å; N116-S119 PolarHBondContact O-N 3.04Å; N116-S119 PolarHBondContact O-OG 2.88Å; N116-S119 VanDerWaalsContact O-OG 3.11Å; N116-S119 VanDerWaalsContact OD1-CB 3.3Å; N116-S119 WeakPolarHBondContact OD1-CB 3.44Å; N116-S119 PolarHBondContact OD1-N 2.93Å; N116-S119 PolarHBondContact OD1-OG 3.36Å; N116-F120 PolarHBondContact O-N 2.88Å; N116-M137 WeakPolarHBondContact CA-SD 3.42Å; N116-M137 PolarHBondContact N-SD 3.47Å; N116-E141 WeakPolarHBondContact CA-OE1 3.37Å; N116-E141 WeakPolarHBondContact CB-OE1 3.44Å
117T73.4Confident65.7Low4 Ų469.2 Ų69.23%0.02537%0.367CS..G310 helixtrans-61.6-32.6-178.864.10000112.7S119 F120 Y122 F134 M137 L138 E141T117-S119 PolarHBondContact O-N 2.64Å; T117-F120 WeakPolarHBondContact O-CB 3.37Å; T117-F120 PolarHBondContact O-N 2.61Å; T117-F120 VanDerWaalsContact O-N 3.12Å; T117-Y122 WeakPolarHBondContact O-CE2 3.4Å; T117-Y122 VanDerWaalsContact O-CZ 3.31Å; T117-Y122 PolarHBondContact O-OH 2.98Å; T117-F134 VanDerWaalsContact CB-CE2 3.44Å; T117-F134 HydrophobicContact CG2-CD2 3.88Å; T117-F134 HydrophobicContact CG2-CE2 3.63Å; T117-F134 HydrophobicContact CG2-CG 4.47Å; T117-F134 HydrophobicContact CG2-CZ 4Å; T117-M137 HydrophobicContact CG2-CB 3.78Å; T117-L138 HydrophobicContact CG2-CB 3.58Å; T117-L138 HydrophobicContact CG2-CD1 3.79Å; T117-L138 HydrophobicContact CG2-CG 4.28Å; T117-E141 WeakPolarHBondContact CB-OE2 3.27Å; T117-E141 WeakPolarHBondContact CG2-OE2 3.32Å; T117-E141 PolarHBondContact N-OE1 2.87Å; T117-E141 PolarHBondContact OG1-OE2 2.95Å
118D55.1Low66.5Low32 Ų3269.3 Ų69.317%0.17136%0.362CS..G310 helixtrans-72.4-29.1-178.5-71.8-44.9000115.4N116 T413 S414N116-D118 PolarHBondContact O-N 2.83Å; D118-T413 WeakPolarHBondContact CB-O 3.43Å; D118-T413 VanDerWaalsContact CG-O 3.25Å; D118-S414 VanDerWaalsContact OD2-CA 3.26Å; D118-S414 WeakPolarHBondContact OD2-CA 3.44Å; D118-S414 WeakPolarHBondContact OD2-CB 2.88Å; D118-S414 PolarHBondContact OD2-OG 2.69Å
119S62.1Low67.6Low51 Ų5172.3 Ų72.336%0.35738%0.382SS..G310 helixtrans-851.8172.1570000112.6R115 N116 T117R115-S119 PolarHBondContact N-OG 2.9Å; N116-S119 PolarHBondContact N-OG 2.67Å; N116-S119 PolarHBondContact O-N 3.04Å; N116-S119 PolarHBondContact O-OG 2.88Å; N116-S119 VanDerWaalsContact O-OG 3.11Å; N116-S119 VanDerWaalsContact OD1-CB 3.3Å; N116-S119 WeakPolarHBondContact OD1-CB 3.44Å; N116-S119 PolarHBondContact OD1-N 2.93Å; N116-S119 PolarHBondContact OD1-OG 3.36Å; T117-S119 PolarHBondContact O-N 2.64Å
120F73.3Confident68.8Low6 Ų671.5 Ų71.53%0.02637%0.367CS..SBendtrans-70.1135.9173.3-161.3-92.1000110.2P114 N116 T117 Y122 H126 E130 F134 M137 L193P114-F120 HydrophobicContact CB-CB 4.28Å; P114-F120 HydrophobicContact CB-CD2 4.02Å; P114-F120 HydrophobicContact CG-CD2 3.65Å; P114-F120 HydrophobicContact CG-CE2 4.2Å; N116-F120 PolarHBondContact O-N 2.88Å; T117-F120 WeakPolarHBondContact O-CB 3.37Å; T117-F120 PolarHBondContact O-N 2.61Å; T117-F120 VanDerWaalsContact O-N 3.12Å; F120-Y122 HydrophobicContact CB-CE2 4.24Å; F120-Y122 HydrophobicContact CD1-CD1 4.36Å; F120-Y122 HydrophobicContact CD1-CE1 4.36Å; F120-Y122 WeakPolarHBondContact O-CD2 3.48Å; F120-Y122 WeakPolarHBondContact O-CE2 3.47Å; F120-Y122 PolarHBondContact O-N 2.77Å; F120-H126 AromaticContact CD1-NE2 3.92Å; F120-H126 AromaticContact CE1-CD2 3.25Å; F120-H126 WeakPolarHBondContact CE1-CD2 3.5Å; F120-H126 AromaticContact CE1-CE1 3.53Å; F120-H126 AromaticContact CE1-CG 3.57Å; F120-H126 AromaticContact CE1-ND1 3.75Å; F120-H126 AromaticContact CE1-NE2 3.22Å; F120-H126 WeakPolarHBondContact CE1-NE2 3.12Å; F120-H126 AromaticContact CE2-ND1 4Å; F120-H126 HydrophobicContact CZ-CB 3.99Å; F120-H126 AromaticContact CZ-CD2 3.54Å; F120-H126 AromaticContact CZ-CE1 3.58Å; F120-H126 AromaticContact CZ-CG 3.3Å; F120-H126 AromaticContact CZ-ND1 3.34Å; F120-H126 VanDerWaalsContact CZ-ND1 3.34Å; F120-H126 WeakPolarHBondContact CZ-ND1 3.49Å; F120-H126 AromaticContact CZ-NE2 3.69Å; F120-E130 HydrophobicContact CE2-CB 4.37Å; F120-F134 HydrophobicContact CB-CD2 3.87Å; F120-F134 HydrophobicContact CB-CE2 4.18Å; F120-F134 AromaticContact CD1-CD2 3.94Å; F120-F134 HydrophobicContact CD1-CD2 3.94Å; F120-F134 HydrophobicContact CD1-CE2 4.38Å; F120-F134 HydrophobicContact CD2-CB 3.93Å; F120-F134 AromaticContact CD2-CD2 3.71Å; F120-F134 HydrophobicContact CD2-CD2 3.71Å; F120-F134 HydrophobicContact CD2-CG 4.28Å; F120-F134 HydrophobicContact CE1-CD2 4.42Å; F120-F134 HydrophobicContact CE2-CB 3.7Å; F120-F134 HydrophobicContact CE2-CD2 4.21Å; F120-F134 HydrophobicContact CE2-CG 4.37Å; F120-F134 AromaticContact CG-CD2 3.55Å; F120-F134 HydrophobicContact CG-CD2 3.55Å; F120-F134 HydrophobicContact CG-CE2 4.19Å; F120-F134 HydrophobicContact CG-CG 4.45Å; F120-F134 HydrophobicContact CZ-CB 4.15Å; F120-M137 HydrophobicContact CD2-CE 4.18Å; F120-L193 HydrophobicContact CD1-CD1 4.33Å; F120-L193 HydrophobicContact CE1-CD1 3.53Å; F120-L193 HydrophobicContact CZ-CD1 4.13Å
121D71.4Confident70.2Confident43 Ų4362.3 Ų62.323%0.2333%0.333CS..  trans-82.287.1-176.2-179.84.6000111.5A123 N124 H126D121-A123 PolarHBondContact O-N 2.97Å; D121-A123 VanDerWaalsContact O-N 3.08Å; D121-A123 WeakPolarHBondContact OD1-CB 3.43Å; D121-A123 PolarHBondContact OD1-N 3.12Å; D121-N124 PolarHBondContact O-N 2.68Å; D121-N124 PolarHBondContact OD2-ND2 3.27Å; D121-H126 PolarHBondContact O-CE1 2.87Å; D121-H126 PolarHBondContact O-NE2 3.16Å
122Y72.8Confident71.8Confident32 Ų3259 Ų5913%0.12531%0.313CS..THydrogen-bonded Turntrans-68-6.8179.6-58-85.5000115.1T117 F120 F134 L193 W194T117-Y122 WeakPolarHBondContact O-CE2 3.4Å; T117-Y122 VanDerWaalsContact O-CZ 3.31Å; T117-Y122 PolarHBondContact O-OH 2.98Å; F120-Y122 HydrophobicContact CB-CE2 4.24Å; F120-Y122 HydrophobicContact CD1-CD1 4.36Å; F120-Y122 HydrophobicContact CD1-CE1 4.36Å; F120-Y122 WeakPolarHBondContact O-CD2 3.48Å; F120-Y122 WeakPolarHBondContact O-CE2 3.47Å; F120-Y122 PolarHBondContact O-N 2.77Å; Y122-F134 AromaticContact CE1-CE2 3.84Å; Y122-F134 HydrophobicContact CE1-CE2 3.84Å; Y122-F134 HydrophobicContact CE1-CZ 4.16Å; Y122-F134 AromaticContact CZ-CE2 3.89Å; Y122-F134 WeakPolarHBondContact OH-CE2 3.37Å; Y122-L193 HydrophobicContact CD1-CB 3.74Å; Y122-L193 VanDerWaalsContact CE1-C 3.47Å; Y122-L193 HydrophobicContact CE1-CB 3.74Å; Y122-L193 WeakPolarHBondContact CE1-O 3.47Å; Y122-W194 HydrophobicContact CD1-CE3 4.4Å; Y122-W194 HydrophobicContact CD2-CE3 4.49Å; Y122-W194 AromaticContact CG-CE3 3.95Å; Y122-W194 HydrophobicContact CG-CE3 3.95Å; Y122-W194 HydrophobicContact CG-CZ3 4.4Å
123A67.9Low73.3Confident88 Ų8856.4 Ų56.473%0.72730%0.3SS*.THydrogen-bonded Turntrans-90.6-9.9-176.900000113.6D121D121-A123 PolarHBondContact O-N 2.97Å; D121-A123 VanDerWaalsContact O-N 3.08Å; D121-A123 WeakPolarHBondContact OD1-CB 3.43Å; D121-A123 PolarHBondContact OD1-N 3.12Å
124N72Confident74.5Confident44 Ų4449.4 Ų49.424%0.23527%0.267CS..SBendtrans-125.6162.4-178.3-71.2-69.3000112A108 D121 H126A108-N124 HydrophobicContact CB-CB 3.82Å; D121-N124 PolarHBondContact O-N 2.68Å; D121-N124 PolarHBondContact OD2-ND2 3.27Å; N124-H126 PolarHBondContact O-CD2 3.43Å; N124-H126 PolarHBondContact O-NE2 3.07Å; N124-H126 VanDerWaalsContact O-NE2 3.13Å
125Y73.9Confident75.9Confident81 Ų8148.9 Ų48.932%0.31826%0.262SS..  trans-77146.8174.1-63.3-56.5000112.1E101 W186E101-Y125 HydrophobicContact CG-CD2 3.92Å; E101-Y125 HydrophobicContact CG-CE2 4.18Å; E101-Y125 VanDerWaalsContact OE1-CD2 3.24Å; E101-Y125 WeakPolarHBondContact OE1-CD2 3.42Å; E101-Y125 WeakPolarHBondContact OE1-CE2 3.48Å; Y125-W186 HydrophobicContact CD1-CB 3.72Å; Y125-W186 HydrophobicContact CD1-CE3 4.46Å; Y125-W186 HydrophobicContact CD2-CE3 4.25Å; Y125-W186 HydrophobicContact CE1-CB 3.73Å; Y125-W186 HydrophobicContact CG-CB 4.29Å; Y125-W186 AromaticContact CG-CE3 3.94Å; Y125-W186 HydrophobicContact CG-CE3 3.94Å
126H76.6Confident77Confident27 Ų2744 Ų4413%0.12525%0.249CC..  trans-122151.2-174.5-68-82.4000112.2F120 D121 N124 E130 I131F120-H126 AromaticContact CD1-NE2 3.92Å; F120-H126 AromaticContact CE1-CD2 3.25Å; F120-H126 WeakPolarHBondContact CE1-CD2 3.5Å; F120-H126 AromaticContact CE1-CE1 3.53Å; F120-H126 AromaticContact CE1-CG 3.57Å; F120-H126 AromaticContact CE1-ND1 3.75Å; F120-H126 AromaticContact CE1-NE2 3.22Å; F120-H126 WeakPolarHBondContact CE1-NE2 3.12Å; F120-H126 AromaticContact CE2-ND1 4Å; F120-H126 HydrophobicContact CZ-CB 3.99Å; F120-H126 AromaticContact CZ-CD2 3.54Å; F120-H126 AromaticContact CZ-CE1 3.58Å; F120-H126 AromaticContact CZ-CG 3.3Å; F120-H126 AromaticContact CZ-ND1 3.34Å; F120-H126 VanDerWaalsContact CZ-ND1 3.34Å; F120-H126 WeakPolarHBondContact CZ-ND1 3.49Å; F120-H126 AromaticContact CZ-NE2 3.69Å; D121-H126 PolarHBondContact O-CE1 2.87Å; D121-H126 PolarHBondContact O-NE2 3.16Å; N124-H126 PolarHBondContact O-CD2 3.43Å; N124-H126 PolarHBondContact O-NE2 3.07Å; N124-H126 VanDerWaalsContact O-NE2 3.13Å; H126-E130 HydrophobicContact CB-CB 4.06Å; H126-I131 HydrophobicContact CB-CD1 4.48Å; H126-I131 HydrophobicContact CB-CG1 3.97Å
127T80.8Confident77.8Confident61 Ų6144.3 Ų44.337%0.37425%0.25SS..  trans-68.3156.4169.365.40000111.1S129 E130 I131T127-S129 PolarHBondContact O-N 2.82Å; T127-S129 PolarHBondContact OG1-OG 3.41Å; T127-E130 VanDerWaalsContact CB-OE2 3.29Å; T127-E130 WeakPolarHBondContact CB-OE2 3.3Å; T127-E130 WeakPolarHBondContact CG2-OE2 3.23Å; T127-E130 PolarHBondContact N-OE2 3.39Å; T127-E130 PolarHBondContact O-N 3.38Å; T127-E130 WeakPolarHBondContact OG1-CG 3.47Å; T127-E130 PolarHBondContact OG1-N 3.12Å; T127-E130 PolarHBondContact OG1-OE2 2.8Å; T127-I131 WeakPolarHBondContact O-CG1 3.48Å; T127-I131 PolarHBondContact O-N 3.48Å
128L80.6Confident78.4Confident73 Ų7344.3 Ų44.338%0.38225%0.25SS..Hα-helixtrans-57.3-34.1176.3-175.461.6000112.8I131 Y132L128-I131 PolarHBondContact O-N 3.4Å; L128-Y132 HydrophobicContact CD1-CD1 4.17Å; L128-Y132 HydrophobicContact CD1-CE1 3.54Å; L128-Y132 HydrophobicContact CD1-CE2 4.46Å; L128-Y132 HydrophobicContact CD2-CE2 4.36Å; L128-Y132 HydrophobicContact CG-CE1 4.03Å; L128-Y132 HydrophobicContact CG-CE2 4.05Å; L128-Y132 PolarHBondContact O-N 2.82Å
129S81.7Confident79.8Confident77 Ų7744.5 Ų44.554%0.53825%0.252SS..Hα-helixtrans-64.8-43.1174.638.10000112.5T127 I131 Y132 S133T127-S129 PolarHBondContact O-N 2.82Å; T127-S129 PolarHBondContact OG1-OG 3.41Å; S129-I131 VanDerWaalsContact C-N 3.33Å; S129-Y132 PolarHBondContact O-N 3Å; S129-S133 PolarHBondContact O-N 3.44Å; S129-S133 PolarHBondContact O-OG 3.31Å
130E81.9Confident80.5Confident47 Ų4745.6 Ų45.622%0.2227%0.265CS..Hα-helixtrans-65.9-38.4177.3-73.2157.6153.500110.9F120 H126 T127 S133 F134F120-E130 HydrophobicContact CE2-CB 4.37Å; H126-E130 HydrophobicContact CB-CB 4.06Å; T127-E130 VanDerWaalsContact CB-OE2 3.29Å; T127-E130 WeakPolarHBondContact CB-OE2 3.3Å; T127-E130 WeakPolarHBondContact CG2-OE2 3.23Å; T127-E130 PolarHBondContact N-OE2 3.39Å; T127-E130 PolarHBondContact O-N 3.38Å; T127-E130 WeakPolarHBondContact OG1-CG 3.47Å; T127-E130 PolarHBondContact OG1-N 3.12Å; T127-E130 PolarHBondContact OG1-OE2 2.8Å; E130-S133 PolarHBondContact O-N 3Å; E130-F134 PolarHBondContact O-N 3.24Å
131I85Confident80.6Confident16 Ų1648.3 Ų48.38%0.08228%0.278CS..Hα-helixtrans-63.4-42.7173.7-64.3170.5000111H126 T127 L128 S129 F134 Q135 Q189H126-I131 HydrophobicContact CB-CD1 4.48Å; H126-I131 HydrophobicContact CB-CG1 3.97Å; T127-I131 WeakPolarHBondContact O-CG1 3.48Å; T127-I131 PolarHBondContact O-N 3.48Å; L128-I131 PolarHBondContact O-N 3.4Å; S129-I131 VanDerWaalsContact C-N 3.33Å; I131-F134 WeakPolarHBondContact O-CB 3.38Å; I131-F134 PolarHBondContact O-N 3.05Å; I131-Q135 VanDerWaalsContact O-CG 3.31Å; I131-Q135 WeakPolarHBondContact O-CG 3.25Å; I131-Q135 PolarHBondContact O-N 3.04Å; I131-Q189 HydrophobicContact CD1-CB 4.35Å
132Y88.8Confident80.7Confident47 Ų4749.1 Ų49.118%0.18428%0.282CS..Hα-helixtrans-64.7-41.1175.4-71.5-7.5000112.3L128 S129 F134 Q135 D136 P159 N161L128-Y132 HydrophobicContact CD1-CD1 4.17Å; L128-Y132 HydrophobicContact CD1-CE1 3.54Å; L128-Y132 HydrophobicContact CD1-CE2 4.46Å; L128-Y132 HydrophobicContact CD2-CE2 4.36Å; L128-Y132 HydrophobicContact CG-CE1 4.03Å; L128-Y132 HydrophobicContact CG-CE2 4.05Å; L128-Y132 PolarHBondContact O-N 2.82Å; S129-Y132 PolarHBondContact O-N 3Å; Y132-F134 VanDerWaalsContact C-N 3.32Å; Y132-F134 PolarHBondContact O-N 2.98Å; Y132-Q135 WeakPolarHBondContact O-CB 3.21Å; Y132-Q135 PolarHBondContact O-N 3.25Å; Y132-D136 PolarHBondContact O-N 2.88Å; Y132-P159 HydrophobicContact CD2-CG 4.48Å; Y132-P159 HydrophobicContact CE2-CG 3.81Å; Y132-P159 PolarHBondContact OH-O 2.85Å; Y132-N161 VanDerWaalsContact CD1-ND2 3.3Å; Y132-N161 WeakPolarHBondContact CD1-ND2 3.29Å; Y132-N161 WeakPolarHBondContact CE1-ND2 3.26Å
133S85.8Confident81Confident59 Ų5951 Ų5141%0.41330%0.298SS..Hα-helixtrans-60.8-41.4173.2-66.10000111.6S129 E130 Q135 D136 M137S129-S133 PolarHBondContact O-N 3.44Å; S129-S133 PolarHBondContact O-OG 3.31Å; E130-S133 PolarHBondContact O-N 3Å; S133-Q135 PolarHBondContact O-N 3.02Å; S133-D136 PolarHBondContact O-N 2.82Å; S133-M137 WeakPolarHBondContact O-CG 3.27Å; S133-M137 PolarHBondContact O-N 2.77Å
134F86.9Confident81.3Confident4 Ų452.4 Ų52.42%0.01829%0.293CS..Hα-helixtrans-58.1-46.7172.3174.2-86.8000112.3T117 F120 Y122 E130 I131 Y132 D136 M137 L138 L193 A196T117-F134 VanDerWaalsContact CB-CE2 3.44Å; T117-F134 HydrophobicContact CG2-CD2 3.88Å; T117-F134 HydrophobicContact CG2-CE2 3.63Å; T117-F134 HydrophobicContact CG2-CG 4.47Å; T117-F134 HydrophobicContact CG2-CZ 4Å; F120-F134 HydrophobicContact CB-CD2 3.87Å; F120-F134 HydrophobicContact CB-CE2 4.18Å; F120-F134 AromaticContact CD1-CD2 3.94Å; F120-F134 HydrophobicContact CD1-CD2 3.94Å; F120-F134 HydrophobicContact CD1-CE2 4.38Å; F120-F134 HydrophobicContact CD2-CB 3.93Å; F120-F134 AromaticContact CD2-CD2 3.71Å; F120-F134 HydrophobicContact CD2-CD2 3.71Å; F120-F134 HydrophobicContact CD2-CG 4.28Å; F120-F134 HydrophobicContact CE1-CD2 4.42Å; F120-F134 HydrophobicContact CE2-CB 3.7Å; F120-F134 HydrophobicContact CE2-CD2 4.21Å; F120-F134 HydrophobicContact CE2-CG 4.37Å; F120-F134 AromaticContact CG-CD2 3.55Å; F120-F134 HydrophobicContact CG-CD2 3.55Å; F120-F134 HydrophobicContact CG-CE2 4.19Å; F120-F134 HydrophobicContact CG-CG 4.45Å; F120-F134 HydrophobicContact CZ-CB 4.15Å; Y122-F134 AromaticContact CE1-CE2 3.84Å; Y122-F134 HydrophobicContact CE1-CE2 3.84Å; Y122-F134 HydrophobicContact CE1-CZ 4.16Å; Y122-F134 AromaticContact CZ-CE2 3.89Å; Y122-F134 WeakPolarHBondContact OH-CE2 3.37Å; E130-F134 PolarHBondContact O-N 3.24Å; I131-F134 WeakPolarHBondContact O-CB 3.38Å; I131-F134 PolarHBondContact O-N 3.05Å; Y132-F134 VanDerWaalsContact C-N 3.32Å; Y132-F134 PolarHBondContact O-N 2.98Å; F134-D136 VanDerWaalsContact C-N 3.27Å; F134-D136 PolarHBondContact O-N 2.94Å; F134-M137 HydrophobicContact CB-CE 4.36Å; F134-M137 PolarHBondContact O-N 3.36Å; F134-L138 HydrophobicContact CE1-CB 4.31Å; F134-L138 HydrophobicContact CE1-CD2 4.04Å; F134-L138 HydrophobicContact CZ-CD2 4.48Å; F134-L138 WeakPolarHBondContact O-CB 3.12Å; F134-L138 PolarHBondContact O-N 3.25Å; F134-L193 HydrophobicContact CB-CD2 4.38Å; F134-L193 HydrophobicContact CD1-CD2 3.14Å; F134-L193 HydrophobicContact CD2-CD2 4.2Å; F134-L193 HydrophobicContact CE1-CB 4.48Å; F134-L193 HydrophobicContact CE1-CD2 3.25Å; F134-L193 HydrophobicContact CE1-CG 4.46Å; F134-L193 HydrophobicContact CE2-CD2 4.27Å; F134-L193 HydrophobicContact CG-CD2 3.65Å; F134-L193 HydrophobicContact CZ-CB 4.32Å; F134-L193 HydrophobicContact CZ-CD2 3.83Å; F134-A196 HydrophobicContact CZ-CB 4.25Å
135Q89.6Confident81.7Confident26 Ų2654 Ų5412%0.12130%0.302CS..Hα-helixtrans-60.1-39.6178.4-69171.8-6.400111.6I131 Y132 S133 V139 K148 N161 L163I131-Q135 VanDerWaalsContact O-CG 3.31Å; I131-Q135 WeakPolarHBondContact O-CG 3.25Å; I131-Q135 PolarHBondContact O-N 3.04Å; Y132-Q135 WeakPolarHBondContact O-CB 3.21Å; Y132-Q135 PolarHBondContact O-N 3.25Å; S133-Q135 PolarHBondContact O-N 3.02Å; Q135-V139 VanDerWaalsContact O-CG2 3.3Å; Q135-V139 WeakPolarHBondContact O-CG2 3.44Å; Q135-V139 PolarHBondContact O-N 3.25Å; Q135-V139 VanDerWaalsContact O-N 3.12Å; Q135-K148 HydrophobicContact CB-CD 4.09Å; Q135-N161 PolarHBondContact OE1-ND2 3.37Å; Q135-L163 HydrophobicContact CB-CD1 4.36Å; Q135-L163 HydrophobicContact CB-CD2 4.07Å; Q135-L163 HydrophobicContact CB-CG 4.41Å; Q135-L163 HydrophobicContact CG-CD1 3.87Å; Q135-L163 HydrophobicContact CG-CD2 4.33Å; Q135-L163 HydrophobicContact CG-CG 4.12Å
136D89Confident82.3Confident83 Ų8350.3 Ų50.344%0.44429%0.287SS..Hα-helixtrans-64.4-44.7174.4-77.1-47.8000112.1Y132 S133 F134 V139 A140 K148Y132-D136 PolarHBondContact O-N 2.88Å; S133-D136 PolarHBondContact O-N 2.82Å; F134-D136 VanDerWaalsContact C-N 3.27Å; F134-D136 PolarHBondContact O-N 2.94Å; D136-V139 PolarHBondContact O-N 2.85Å; D136-A140 WeakPolarHBondContact O-CB 3.46Å; D136-A140 PolarHBondContact O-N 3.28Å; D136-K148 WeakPolarHBondContact OD1-CE 3.44Å; D136-K148 IonicContact OD1-NZ 2.73Å; D136-K148 PolarHBondContact OD1-NZ 2.95Å; D136-K148 IonicContact OD2-NZ 2.61Å; D136-K148 PolarHBondContact OD2-NZ 2.8Å
137M86.2Confident83Confident29 Ų2951.3 Ų51.314%0.14330%0.297CS..Hα-helixtrans-60.5-45.7175.3-69.5-174.8-61.900111.3P114 N116 T117 F120 S133 F134 V139 A140 E141P114-M137 HydrophobicContact CB-CE 4.14Å; P114-M137 HydrophobicContact CG-CE 4.13Å; N116-M137 WeakPolarHBondContact CA-SD 3.42Å; N116-M137 PolarHBondContact N-SD 3.47Å; T117-M137 HydrophobicContact CG2-CB 3.78Å; F120-M137 HydrophobicContact CD2-CE 4.18Å; S133-M137 WeakPolarHBondContact O-CG 3.27Å; S133-M137 PolarHBondContact O-N 2.77Å; F134-M137 HydrophobicContact CB-CE 4.36Å; F134-M137 PolarHBondContact O-N 3.36Å; M137-V139 VanDerWaalsContact C-N 3.33Å; M137-V139 PolarHBondContact O-N 2.97Å; M137-A140 PolarHBondContact O-N 3.09Å; M137-A140 VanDerWaalsContact O-N 3.12Å; M137-E141 WeakPolarHBondContact O-CB 3.42Å; M137-E141 VanDerWaalsContact O-CG 3.27Å; M137-E141 WeakPolarHBondContact O-CG 3.24Å; M137-E141 PolarHBondContact O-N 3.36Å
138L84.3Confident83.6Confident5 Ų551.5 Ų51.53%0.02629%0.293CS..Hα-helixtrans-62.7-40.4-178.5-168.866.8000112.3T117 F134 N142 V146 L163 F165 A196T117-L138 HydrophobicContact CG2-CB 3.58Å; T117-L138 HydrophobicContact CG2-CD1 3.79Å; T117-L138 HydrophobicContact CG2-CG 4.28Å; F134-L138 HydrophobicContact CE1-CB 4.31Å; F134-L138 HydrophobicContact CE1-CD2 4.04Å; F134-L138 HydrophobicContact CZ-CD2 4.48Å; F134-L138 WeakPolarHBondContact O-CB 3.12Å; F134-L138 PolarHBondContact O-N 3.25Å; L138-N142 WeakPolarHBondContact O-CB 3.48Å; L138-N142 PolarHBondContact O-N 3.25Å; L138-N142 PolarHBondContact O-ND2 2.97Å; L138-V146 HydrophobicContact CD2-CG1 4.2Å; L138-V146 HydrophobicContact CG-CG1 4.28Å; L138-L163 HydrophobicContact CD2-CD1 3.75Å; L138-F165 HydrophobicContact CD2-CE1 4.15Å; L138-F165 HydrophobicContact CD2-CZ 3.9Å; L138-A196 HydrophobicContact CD1-CB 3.93Å; L138-A196 HydrophobicContact CD2-CB 4.07Å
139V85.2Confident84.2Confident35 Ų3551.3 Ų51.321%0.21229%0.292CS..Hα-helixtrans-66.8-42.7174.4171.10000111.1Q135 D136 M137 E141 N142 P143 V146 K148 L163Q135-V139 VanDerWaalsContact O-CG2 3.3Å; Q135-V139 WeakPolarHBondContact O-CG2 3.44Å; Q135-V139 PolarHBondContact O-N 3.25Å; Q135-V139 VanDerWaalsContact O-N 3.12Å; D136-V139 PolarHBondContact O-N 2.85Å; M137-V139 VanDerWaalsContact C-N 3.33Å; M137-V139 PolarHBondContact O-N 2.97Å; V139-E141 VanDerWaalsContact C-N 3.29Å; V139-E141 PolarHBondContact O-N 2.83Å; V139-N142 CarbonylContact O-C 3.6Å; V139-N142 PolarHBondContact O-N 2.84Å; V139-P143 VanDerWaalsContact O-CA 3.28Å; V139-P143 WeakPolarHBondContact O-CA 3.19Å; V139-P143 VanDerWaalsContact O-N 3.14Å; V139-V146 HydrophobicContact CG2-CG1 3.98Å; V139-K148 HydrophobicContact CG2-CB 3.8Å; V139-L163 HydrophobicContact CG2-CD2 3.73Å
140A76.1Confident84.8Confident75 Ų7551.7 Ų51.762%0.6229%0.291SS*.Hα-helixtrans-64.1-36.3178.700000112.1D136 M137D136-A140 WeakPolarHBondContact O-CB 3.46Å; D136-A140 PolarHBondContact O-N 3.28Å; M137-A140 PolarHBondContact O-N 3.09Å; M137-A140 VanDerWaalsContact O-N 3.12Å
141E75.2Confident85.3Confident62 Ų6254.4 Ų54.429%0.2931%0.305SS..Hα-helixtrans-77.2-28.9178.5-72.1162.4-149.100112.9N116 T117 M137 V139 P143N116-E141 WeakPolarHBondContact CA-OE1 3.37Å; N116-E141 WeakPolarHBondContact CB-OE1 3.44Å; T117-E141 WeakPolarHBondContact CB-OE2 3.27Å; T117-E141 WeakPolarHBondContact CG2-OE2 3.32Å; T117-E141 PolarHBondContact N-OE1 2.87Å; T117-E141 PolarHBondContact OG1-OE2 2.95Å; M137-E141 WeakPolarHBondContact O-CB 3.42Å; M137-E141 VanDerWaalsContact O-CG 3.27Å; M137-E141 WeakPolarHBondContact O-CG 3.24Å; M137-E141 PolarHBondContact O-N 3.36Å; V139-E141 VanDerWaalsContact C-N 3.29Å; V139-E141 PolarHBondContact O-N 2.83Å; E141-P143 VanDerWaalsContact C-CD 3.43Å
142N74.5Confident85.7Confident61 Ų6155 Ų5533%0.32632%0.316SS..  trans-128.850.8-174-56.6-85.4000113.2L138 V139 N144 L145 V146L138-N142 WeakPolarHBondContact O-CB 3.48Å; L138-N142 PolarHBondContact O-N 3.25Å; L138-N142 PolarHBondContact O-ND2 2.97Å; V139-N142 CarbonylContact O-C 3.6Å; V139-N142 PolarHBondContact O-N 2.84Å; N142-N144 PolarHBondContact O-N 3.32Å; N142-L145 PolarHBondContact O-N 2.74Å; N142-V146 HydrophobicContact CB-CB 4.06Å; N142-V146 HydrophobicContact CB-CG2 3.6Å; N142-V146 PolarHBondContact O-N 3.33Å
143P79.4Confident85.9Confident71 Ų7159.5 Ų59.546%0.46134%0.338SS..THydrogen-bonded Turntrans-66-19.4-165.726.9-36.6000114.7V139 E141V139-P143 VanDerWaalsContact O-CA 3.28Å; V139-P143 WeakPolarHBondContact O-CA 3.19Å; V139-P143 VanDerWaalsContact O-N 3.14Å; E141-P143 VanDerWaalsContact C-CD 3.43Å
144N74.4Confident86Confident117 Ų11758.5 Ų58.563%0.62633%0.332SS*.THydrogen-bonded Turntrans-91.7-12.1179.2-63.6-41.3000113.5N142N142-N144 PolarHBondContact O-N 3.32Å
145L78.9Confident85.9Confident79 Ų7969.6 Ų69.641%0.41438%0.375SS..THydrogen-bonded Turntrans-116-40.4-178179.863.2000110.9N142 F165 S166 T167N142-L145 PolarHBondContact O-N 2.74Å; L145-F165 CarbonylContact O-C 3.45Å; L145-F165 WeakPolarHBondContact O-CA 2.97Å; L145-S166 PolarHBondContact O-N 2.68Å; L145-T167 HydrophobicContact CD1-CG2 4.2Å
146V87.8Confident85.6Confident3 Ų374.8 Ų74.82%0.01840%0.399CS..EExtended strand (participates in β ladder)trans-114.2128.4-171.7-168.20000109.4L138 V139 N142 L163 K164 F165L138-V146 HydrophobicContact CD2-CG1 4.2Å; L138-V146 HydrophobicContact CG-CG1 4.28Å; V139-V146 HydrophobicContact CG2-CG1 3.98Å; N142-V146 HydrophobicContact CB-CB 4.06Å; N142-V146 HydrophobicContact CB-CG2 3.6Å; N142-V146 PolarHBondContact O-N 3.33Å; V146-L163 HydrophobicContact CG1-CB 4.32Å; V146-L163 HydrophobicContact CG1-CD2 3.86Å; V146-K164 CarbonylContact C-O 3.56Å; V146-K164 WeakPolarHBondContact CA-O 3.14Å; V146-F165 HydrophobicContact CB-CE1 4.42Å; V146-F165 HydrophobicContact CG1-CD1 4.43Å; V146-F165 HydrophobicContact CG1-CE1 4.06Å; V146-F165 HydrophobicContact CG1-CZ 4.17Å; V146-F165 HydrophobicContact CG2-CD1 3.51Å; V146-F165 HydrophobicContact CG2-CE1 3.46Å; V146-F165 VanDerWaalsContact CG2-CE1 3.46Å; V146-F165 HydrophobicContact CG2-CG 4.43Å; V146-F165 HydrophobicContact CG2-CZ 4.37Å
147S91.2Very high85.5Confident48 Ų4872.8 Ų72.834%0.33640%0.398SS..EExtended strand (participates in β ladder)trans-130.3142.3172.354.40000109.8L163 K164S147-L163 CarbonylContact O-C 3.43Å; S147-L163 WeakPolarHBondContact O-CA 3.33Å; S147-K164 PolarHBondContact N-O 3.13Å; S147-K164 PolarHBondContact O-N 2.83Å; S147-K164 PolarHBondContact OG-O 3.06Å
148K92.3Very high85.7Confident64 Ų6476.6 Ų76.628%0.27841%0.411SS..EExtended strand (participates in β ladder)trans-94125173.5-177.5167.869168.70109.8Q135 D136 V139 N161 V162 L163Q135-K148 HydrophobicContact CB-CD 4.09Å; D136-K148 WeakPolarHBondContact OD1-CE 3.44Å; D136-K148 IonicContact OD1-NZ 2.73Å; D136-K148 PolarHBondContact OD1-NZ 2.95Å; D136-K148 IonicContact OD2-NZ 2.61Å; D136-K148 PolarHBondContact OD2-NZ 2.8Å; V139-K148 HydrophobicContact CG2-CB 3.8Å; K148-N161 HydrophobicContact CD-CB 4.05Å; K148-N161 HydrophobicContact CG-CB 4.14Å; K148-V162 CarbonylContact C-O 3.59Å; K148-V162 WeakPolarHBondContact CA-O 3.5Å; K148-L163 HydrophobicContact CB-CD2 4.17Å
149I93Very high86Confident70 Ų7078.5 Ų78.536%0.35942%0.423SS..EExtended strand (participates in β ladder)trans-114.8127.6178.7-55.9175.3000107.9I151 N161 V162 K164I149-I151 HydrophobicContact CG2-CG2 3.96Å; I149-N161 CarbonylContact O-C 3.52Å; I149-N161 WeakPolarHBondContact O-CA 3.21Å; I149-V162 HydrophobicContact CB-CB 4.5Å; I149-V162 PolarHBondContact N-O 2.92Å; I149-V162 PolarHBondContact O-N 2.69Å; I149-K164 HydrophobicContact CD1-CB 3.77Å; I149-K164 HydrophobicContact CD1-CD 3.8Å; I149-K164 HydrophobicContact CD1-CG 4.41Å; I149-K164 HydrophobicContact CG1-CB 4.43Å
150V94.3Very high86.2Confident85 Ų8580.5 Ų80.552%0.51543%0.433SS..EExtended strand (participates in β ladder)trans-90.3110.9170.2-175.70000107.7G152 P159 L160V150-G152 WeakPolarHBondContact CG1-O 3.42Å; V150-P159 HydrophobicContact CG1-CB 4.03Å; V150-L160 WeakPolarHBondContact CA-O 3.44Å
151I93.3Very high86.9Confident103 Ų10378.2 Ų78.253%0.52841%0.41SS..EExtended strand (participates in β ladder)trans-91-8.7-176.860163.9000113.1I149 L160 V162 W176I149-I151 HydrophobicContact CG2-CG2 3.96Å; I151-L160 HydrophobicContact CD1-CB 4.47Å; I151-L160 HydrophobicContact CG1-CB 3.84Å; I151-L160 WeakPolarHBondContact CG1-O 3.22Å; I151-L160 PolarHBondContact N-O 2.9Å; I151-V162 HydrophobicContact CB-CG2 4.46Å; I151-V162 HydrophobicContact CD1-CG2 3.72Å; I151-V162 HydrophobicContact CG1-CG2 3.94Å; I151-V162 HydrophobicContact CG2-CB 4.31Å; I151-V162 HydrophobicContact CG2-CG2 3.69Å; I151-W176 HydrophobicContact CD1-CH2 4.19Å
152G93.3Very high87.6Confident29 Ų2976.8 Ų76.830%0.29941%0.406SS..EExtended strand (participates in β ladder)trans166.9-163.1-179.700000111.5V150 L160V150-G152 WeakPolarHBondContact CG1-O 3.42Å; G152-L160 PolarHBondContact O-N 3.48Å
153Q93.5Very high88.3Confident141 Ų14175.8 Ų75.866%0.65940%0.4SS*.EExtended strand (participates in β ladder)trans-133.8146.4174.5-65.6177.5-0.900109.4R158Q153-R158 CarbonylContact C-O 3.48Å; Q153-R158 VanDerWaalsContact CA-O 3.26Å; Q153-R158 WeakPolarHBondContact CA-O 3.48Å
154S87Confident88.8Confident39 Ų3977.1 Ų77.127%0.27340%0.398SS..  trans-64.5166.5167.162.30000111E156 G157 R158S154-E156 PolarHBondContact O-N 3.35Å; S154-G157 WeakPolarHBondContact O-CA 3.23Å; S154-G157 PolarHBondContact O-N 2.87Å; S154-R158 PolarHBondContact N-O 3.14Å; S154-R158 WeakPolarHBondContact OG-CB 3.44Å; S154-R158 PolarHBondContact OG-N 3.41Å; S154-R158 PolarHBondContact OG-O 3Å
155Y84.5Confident89.5Confident236 Ų23677.1 Ų77.193%0.92539%0.393SS*.THydrogen-bonded Turntrans-54.1-36.9175.6179.8-96.3000112.9G157Y155-G157 PolarHBondContact O-N 3.39Å
156E85.3Confident89.7Confident135 Ų13575 Ų7563%0.63139%0.385SS*.THydrogen-bonded Turntrans-83.711.9177.9-59-172.7152.200113.2S154 R158S154-E156 PolarHBondContact O-N 3.35Å; E156-R158 PolarHBondContact O-N 3.1Å; E156-R158 IonicContact OE2-CZ 3.33Å; E156-R158 IonicContact OE2-NH1 2.65Å; E156-R158 PolarHBondContact OE2-NH1 2.79Å; E156-R158 IonicContact OE2-NH2 3.59Å; E156-R158 PolarHBondContact OE2-NH2 3.46Å
157G86.8Confident89.5Confident41 Ų4180.4 Ų80.442%0.42342%0.418SS..SBendtrans81.16.1173.800000115.7S154 Y155S154-G157 WeakPolarHBondContact O-CA 3.23Å; S154-G157 PolarHBondContact O-N 2.87Å; Y155-G157 PolarHBondContact O-N 3.39Å
158R88.5Confident88.8Confident110 Ų11079.7 Ų79.742%0.41542%0.418SS..  trans-75.2139.4176.4-54.9-170.8-168.2766.6111.6Q153 S154 E156Q153-R158 CarbonylContact C-O 3.48Å; Q153-R158 VanDerWaalsContact CA-O 3.26Å; Q153-R158 WeakPolarHBondContact CA-O 3.48Å; S154-R158 PolarHBondContact N-O 3.14Å; S154-R158 WeakPolarHBondContact OG-CB 3.44Å; S154-R158 PolarHBondContact OG-N 3.41Å; S154-R158 PolarHBondContact OG-O 3Å; E156-R158 PolarHBondContact O-N 3.1Å; E156-R158 IonicContact OE2-CZ 3.33Å; E156-R158 IonicContact OE2-NH1 2.65Å; E156-R158 PolarHBondContact OE2-NH1 2.79Å; E156-R158 IonicContact OE2-NH2 3.59Å; E156-R158 PolarHBondContact OE2-NH2 3.46Å
159P91.3Very high87.9Confident44 Ų4479.4 Ų79.429%0.28643%0.433SS..EExtended strand (participates in β ladder)trans-68.6136-17829.4-35.7000112.1Y132 V150 N161Y132-P159 HydrophobicContact CD2-CG 4.48Å; Y132-P159 HydrophobicContact CE2-CG 3.81Å; Y132-P159 PolarHBondContact OH-O 2.85Å; V150-P159 HydrophobicContact CG1-CB 4.03Å; P159-N161 PolarHBondContact O-N 3.06Å
160L90.2Very high87.2Confident77 Ų7781.4 Ų81.440%0.40345%0.453SS..EExtended strand (participates in β ladder)trans-90.496.8171.9-58.6179.8000108.2V150 I151 G152V150-L160 WeakPolarHBondContact CA-O 3.44Å; I151-L160 HydrophobicContact CD1-CB 4.47Å; I151-L160 HydrophobicContact CG1-CB 3.84Å; I151-L160 WeakPolarHBondContact CG1-O 3.22Å; I151-L160 PolarHBondContact N-O 2.9Å; G152-L160 PolarHBondContact O-N 3.48Å
161N90.1Very high86.6Confident28 Ų2885.7 Ų85.715%0.1547%0.473CS..EExtended strand (participates in β ladder)trans-89136.3-176.3-62.3-26.3000111.2Y132 Q135 K148 I149 P159Y132-N161 VanDerWaalsContact CD1-ND2 3.3Å; Y132-N161 WeakPolarHBondContact CD1-ND2 3.29Å; Y132-N161 WeakPolarHBondContact CE1-ND2 3.26Å; Q135-N161 PolarHBondContact OE1-ND2 3.37Å; K148-N161 HydrophobicContact CD-CB 4.05Å; K148-N161 HydrophobicContact CG-CB 4.14Å; I149-N161 CarbonylContact O-C 3.52Å; I149-N161 WeakPolarHBondContact O-CA 3.21Å; P159-N161 PolarHBondContact O-N 3.06Å
162V90.1Very high86Confident32 Ų3287.8 Ų87.819%0.19448%0.475CS..EExtended strand (participates in β ladder)trans-120.7129.4170.4176.40000108.2K148 I149 I151 W176K148-V162 CarbonylContact C-O 3.59Å; K148-V162 WeakPolarHBondContact CA-O 3.5Å; I149-V162 HydrophobicContact CB-CB 4.5Å; I149-V162 PolarHBondContact N-O 2.92Å; I149-V162 PolarHBondContact O-N 2.69Å; I151-V162 HydrophobicContact CB-CG2 4.46Å; I151-V162 HydrophobicContact CD1-CG2 3.72Å; I151-V162 HydrophobicContact CG1-CG2 3.94Å; I151-V162 HydrophobicContact CG2-CB 4.31Å; I151-V162 HydrophobicContact CG2-CG2 3.69Å; V162-W176 HydrophobicContact CG1-CH2 4.29Å; V162-W176 HydrophobicContact CG1-CZ3 4.16Å; V162-W176 HydrophobicContact CG2-CH2 3.61Å; V162-W176 HydrophobicContact CG2-CZ2 4.47Å; V162-W176 HydrophobicContact CG2-CZ3 4.22Å
163L90.1Very high85.6Confident40 Ų4092.9 Ų92.921%0.20950%0.503CS..EExtended strand (participates in β ladder)trans-88.1115.5167.9-69.5173.3000109Q135 L138 V139 V146 S147 K148 F165Q135-L163 HydrophobicContact CB-CD1 4.36Å; Q135-L163 HydrophobicContact CB-CD2 4.07Å; Q135-L163 HydrophobicContact CB-CG 4.41Å; Q135-L163 HydrophobicContact CG-CD1 3.87Å; Q135-L163 HydrophobicContact CG-CD2 4.33Å; Q135-L163 HydrophobicContact CG-CG 4.12Å; L138-L163 HydrophobicContact CD2-CD1 3.75Å; V139-L163 HydrophobicContact CG2-CD2 3.73Å; V146-L163 HydrophobicContact CG1-CB 4.32Å; V146-L163 HydrophobicContact CG1-CD2 3.86Å; S147-L163 CarbonylContact O-C 3.43Å; S147-L163 WeakPolarHBondContact O-CA 3.33Å; K148-L163 HydrophobicContact CB-CD2 4.17Å; L163-F165 HydrophobicContact CB-CD2 4.45Å; L163-F165 HydrophobicContact CB-CE2 3.65Å; L163-F165 HydrophobicContact CB-CZ 4.15Å; L163-F165 HydrophobicContact CD1-CZ 4.4Å
164K89.8Confident85.2Confident98 Ų9890.9 Ų90.943%0.42651%0.51SS..EExtended strand (participates in β ladder)trans-96.1119174.2174-176.3175.9-174.80109.4V146 S147 I149V146-K164 CarbonylContact C-O 3.56Å; V146-K164 WeakPolarHBondContact CA-O 3.14Å; S147-K164 PolarHBondContact N-O 3.13Å; S147-K164 PolarHBondContact O-N 2.83Å; S147-K164 PolarHBondContact OG-O 3.06Å; I149-K164 HydrophobicContact CD1-CB 3.77Å; I149-K164 HydrophobicContact CD1-CD 3.8Å; I149-K164 HydrophobicContact CD1-CG 4.41Å; I149-K164 HydrophobicContact CG1-CB 4.43Å
165F88.9Confident85.1Confident118 Ų11896.5 Ų96.552%0.51854%0.536SS..EExtended strand (participates in β ladder)trans-97.7116.8172.5-59.5-100.9000109.1L138 L145 V146 L163L138-F165 HydrophobicContact CD2-CE1 4.15Å; L138-F165 HydrophobicContact CD2-CZ 3.9Å; L145-F165 CarbonylContact O-C 3.45Å; L145-F165 WeakPolarHBondContact O-CA 2.97Å; V146-F165 HydrophobicContact CB-CE1 4.42Å; V146-F165 HydrophobicContact CG1-CD1 4.43Å; V146-F165 HydrophobicContact CG1-CE1 4.06Å; V146-F165 HydrophobicContact CG1-CZ 4.17Å; V146-F165 HydrophobicContact CG2-CD1 3.51Å; V146-F165 HydrophobicContact CG2-CE1 3.46Å; V146-F165 VanDerWaalsContact CG2-CE1 3.46Å; V146-F165 HydrophobicContact CG2-CG 4.43Å; V146-F165 HydrophobicContact CG2-CZ 4.37Å; L163-F165 HydrophobicContact CB-CD2 4.45Å; L163-F165 HydrophobicContact CB-CE2 3.65Å; L163-F165 HydrophobicContact CB-CZ 4.15Å; L163-F165 HydrophobicContact CD1-CZ 4.4Å
166S83.6Confident85.2Confident33 Ų3393.3 Ų93.323%0.23152%0.522CS..  trans-160.4135.5-175.3-178.30000111.6L145 G168L145-S166 PolarHBondContact O-N 2.68Å; S166-G168 PolarHBondContact O-N 3.37Å; S166-G168 PolarHBondContact OG-N 3.26Å
167T82.5Confident85Confident118 Ų11893 Ų9372%0.72452%0.523SS*.SBendtrans-82.610.3171.1560000113.3L145 R172L145-T167 HydrophobicContact CD1-CG2 4.2Å; T167-R172 PolarHBondContact OG1-NH1 2.81Å
168G77.6Confident84.8Confident32 Ų3294.9 Ų94.933%0.3352%0.524SS..SBendtrans104.5-171.5-179.300000114.7S166 R172S166-G168 PolarHBondContact O-N 3.37Å; S166-G168 PolarHBondContact OG-N 3.26Å; G168-R172 PolarHBondContact O-NE 2.91Å; G168-R172 PolarHBondContact O-NH1 3.34Å
169G72.6Confident84.2Confident58 Ų5892.3 Ų92.360%0.59852%0.52SS*.  trans86.4157.3-176.300000114.7
170S77.8Confident83.3Confident112 Ų11291.3 Ų91.378%0.78352%0.518SS*.SBendtrans-104.5146.5177.353.20000111.4R172S170-R172 PolarHBondContact O-N 3.49Å
171N82Confident82.6Confident175 Ų17593.5 Ų93.594%0.93653%0.529SS*.SBendtrans59.835171.9-134.633.8000116.3
172R81.6Confident81.9Confident147 Ų14796.7 Ų96.756%0.55554%0.543SS*.  trans-79.8147.9174.2-66.8-175.5175.7177.21.7111.2T167 G168 S170T167-R172 PolarHBondContact OG1-NH1 2.81Å; G168-R172 PolarHBondContact O-NE 2.91Å; G168-R172 PolarHBondContact O-NH1 3.34Å; S170-R172 PolarHBondContact O-N 3.49Å
173P84.8Confident80.9Confident137 Ų137100.5 Ų100.589%0.8957%0.571SS**  trans-52.6141.1165.9-23.433.6000110.7
174A84.1Confident79.9Confident99 Ų99106.3 Ų106.382%0.81859%0.59SS**  trans-128148-176.800000110.7
175I85.4Confident79Confident157 Ų157104.8 Ų104.881%0.80558%0.584SS**  trans-104.5130.2170.8-58.5174.3000106.7I177I175-I177 HydrophobicContact CG2-CG1 4.08Å
176W85.9Confident78Confident168 Ų168104 Ų10464%0.63658%0.578SS**  trans-100.2124.9173-175.2-88.8000109.2I151 V162I151-W176 HydrophobicContact CD1-CH2 4.19Å; V162-W176 HydrophobicContact CG1-CH2 4.29Å; V162-W176 HydrophobicContact CG1-CZ3 4.16Å; V162-W176 HydrophobicContact CG2-CH2 3.61Å; V162-W176 HydrophobicContact CG2-CZ2 4.47Å; V162-W176 HydrophobicContact CG2-CZ3 4.22Å
177I81.1Confident77.3Confident129 Ų129106.3 Ų106.366%0.66259%0.59SS**  trans-119.4118174.7-54.7176.8000106.5I175 T179I175-I177 HydrophobicContact CG2-CG1 4.08Å; I177-T179 HydrophobicContact CG2-CG2 4.06Å
178D82Confident76.7Confident80 Ų80102.7 Ų102.743%0.42857%0.568SS.*  trans-99.1129.3173.6-171.5-69.8000109.4G180 I181D178-G180 PolarHBondContact OD1-N 2.98Å; D178-I181 WeakPolarHBondContact OD1-CB 3.44Å; D178-I181 PolarHBondContact OD1-N 2.92Å
179T76Confident76.3Confident56 Ų56103.7 Ų103.734%0.34456%0.564SS.*SBendtrans-129.163.5178.659.70000110I177 T188 Q189I177-T179 HydrophobicContact CG2-CG2 4.06Å; T179-T188 WeakPolarHBondContact CB-O 3.41Å; T179-Q189 WeakPolarHBondContact O-CG 3.34Å
180G73.1Confident76Confident23 Ų23102 Ų10224%0.23755%0.545CS..  trans14926.6169.800000117.2D178 H182D178-G180 PolarHBondContact OD1-N 2.98Å; G180-H182 VanDerWaalsContact C-N 3.27Å; G180-H182 PolarHBondContact O-N 3.41Å
181I75.3Confident75.5Confident123 Ų12399.2 Ų99.263%0.63153%0.525SS*.SBendtrans-58.8-33.5-179.6-161.6159000114.1D178D178-I181 WeakPolarHBondContact OD1-CB 3.44Å; D178-I181 PolarHBondContact OD1-N 2.92Å
182H75Confident74.7Confident95 Ų9592 Ų9244%0.4449%0.493SS..SBendtrans-97.5125.5172.9-53.2122.9000110.6G180 R184 E185G180-H182 VanDerWaalsContact C-N 3.27Å; G180-H182 PolarHBondContact O-N 3.41Å; H182-R184 HydrophobicContact CB-CG 4.4Å; H182-R184 PolarHBondContact O-N 3.32Å; H182-E185 HydrophobicContact CB-CG 3.92Å; H182-E185 IonicContact CE1-OE1 2.58Å; H182-E185 IonicContact CG-OE1 3.11Å; H182-E185 IonicContact CG-OE2 3.66Å; H182-E185 IonicContact ND1-OE1 2.91Å; H182-E185 PolarHBondContact ND1-OE1 3.45Å; H182-E185 IonicContact ND1-OE2 3.8Å; H182-E185 PolarHBondContact ND1-OE2 3.29Å; H182-E185 PolarHBondContact O-N 3.16Å
183S69.8Low74Confident112 Ų11285.7 Ų85.778%0.78347%0.47SS*.THydrogen-bonded Turntrans-63.7-7.7-175.7-49.30000115.4W186S183-W186 PolarHBondContact O-NE1 3.46Å
184R68.6Low72.8Confident162 Ų16285.4 Ų85.461%0.61145%0.451SS*.THydrogen-bonded Turntrans-98.6-0.3177.762.4-177.6174.5-177.61.1114.3V53 H182V53-R184 PolarHBondContact O-NH1 3.13Å; H182-R184 HydrophobicContact CB-CG 4.4Å; H182-R184 PolarHBondContact O-N 3.32Å
185E71.3Confident71.8Confident66 Ų6688.6 Ų88.631%0.30845%0.446SS..  trans-103.666.8-174.2-69175.217300112.6H182 V187 T188H182-E185 HydrophobicContact CB-CG 3.92Å; H182-E185 IonicContact CE1-OE1 2.58Å; H182-E185 IonicContact CG-OE1 3.11Å; H182-E185 IonicContact CG-OE2 3.66Å; H182-E185 IonicContact ND1-OE1 2.91Å; H182-E185 PolarHBondContact ND1-OE1 3.45Å; H182-E185 IonicContact ND1-OE2 3.8Å; H182-E185 PolarHBondContact ND1-OE2 3.29Å; H182-E185 PolarHBondContact O-N 3.16Å; E185-V187 PolarHBondContact O-N 3.42Å; E185-T188 HydrophobicContact CB-CG2 4.08Å; E185-T188 PolarHBondContact O-N 3.15Å; E185-T188 PolarHBondContact O-OG1 2.91Å
186W68.1Low70.5Confident103 Ų10382.7 Ų82.739%0.3942%0.421SS..Hα-helixtrans-68.2-24.6-173.1-68.225000113M105 Y125 S183 T188 Q189 A190M105-W186 HydrophobicContact CE-CH2 4.29Å; M105-W186 HydrophobicContact CE-CZ3 3.61Å; M105-W186 HydrophobicContact SD-CE3 4.5Å; M105-W186 HydrophobicContact SD-CH2 4.36Å; M105-W186 HydrophobicContact SD-CZ3 3.57Å; M105-W186 VanDerWaalsContact SD-CZ3 3.57Å; Y125-W186 HydrophobicContact CD1-CB 3.72Å; Y125-W186 HydrophobicContact CD1-CE3 4.46Å; Y125-W186 HydrophobicContact CD2-CE3 4.25Å; Y125-W186 HydrophobicContact CE1-CB 3.73Å; Y125-W186 HydrophobicContact CG-CB 4.29Å; Y125-W186 AromaticContact CG-CE3 3.94Å; Y125-W186 HydrophobicContact CG-CE3 3.94Å; S183-W186 PolarHBondContact O-NE1 3.46Å; W186-T188 VanDerWaalsContact C-N 3.35Å; W186-T188 PolarHBondContact O-N 3.25Å; W186-Q189 PolarHBondContact O-N 3.48Å; W186-A190 PolarHBondContact O-N 2.68Å
187V68.3Low69.3Low81 Ų8177.1 Ų77.149%0.49140%0.401SS..Hα-helixtrans-66.8-30.8176.969.70000113.6E185 A190 S191E185-V187 PolarHBondContact O-N 3.42Å; V187-A190 PolarHBondContact O-N 3.23Å; V187-S191 WeakPolarHBondContact O-CB 3.4Å; V187-S191 PolarHBondContact O-N 2.87Å; V187-S191 PolarHBondContact O-OG 3.46Å
188T70.8Confident68.7Low41 Ų4175.9 Ų75.925%0.25239%0.392SS..Hα-helixtrans-71.4-38.6-178.560.50000110.2T179 E185 W186 S191 G192T179-T188 WeakPolarHBondContact CB-O 3.41Å; E185-T188 HydrophobicContact CB-CG2 4.08Å; E185-T188 PolarHBondContact O-N 3.15Å; E185-T188 PolarHBondContact O-OG1 2.91Å; W186-T188 VanDerWaalsContact C-N 3.35Å; W186-T188 PolarHBondContact O-N 3.25Å; T188-S191 PolarHBondContact O-N 3.01Å; T188-G192 PolarHBondContact O-N 3.18Å
189Q68.6Low68.6Low53 Ų5374.5 Ų74.525%0.24839%0.386CS..Hα-helixtrans-61.2-48.2173.3-66173.23.300111.5I131 T179 W186 S191 G192 L193I131-Q189 HydrophobicContact CD1-CB 4.35Å; T179-Q189 WeakPolarHBondContact O-CG 3.34Å; W186-Q189 PolarHBondContact O-N 3.48Å; Q189-S191 VanDerWaalsContact C-N 3.33Å; Q189-S191 PolarHBondContact O-N 2.85Å; Q189-G192 PolarHBondContact O-N 3.4Å; Q189-L193 WeakPolarHBondContact O-CG 3.48Å; Q189-L193 PolarHBondContact O-N 2.91Å
190A65.7Low69.1Low23 Ų2371.9 Ų71.919%0.1937%0.37CS..Hα-helixtrans-60.5-41.5177.100000112.5W186 V187 G192 L193 W194W186-A190 PolarHBondContact O-N 2.68Å; V187-A190 PolarHBondContact O-N 3.23Å; A190-G192 VanDerWaalsContact C-N 3.31Å; A190-G192 PolarHBondContact O-N 2.86Å; A190-L193 WeakPolarHBondContact O-CB 3.02Å; A190-L193 PolarHBondContact O-N 3.42Å; A190-W194 PolarHBondContact O-N 2.77Å
191S67.2Low69.7Low54 Ų5476.5 Ų76.538%0.37839%0.385SS..Hα-helixtrans-61.1-39.3175.9-56.60000112.2V187 T188 Q189 L193 W194 F195V187-S191 WeakPolarHBondContact O-CB 3.4Å; V187-S191 PolarHBondContact O-N 2.87Å; V187-S191 PolarHBondContact O-OG 3.46Å; T188-S191 PolarHBondContact O-N 3.01Å; Q189-S191 VanDerWaalsContact C-N 3.33Å; Q189-S191 PolarHBondContact O-N 2.85Å; S191-L193 VanDerWaalsContact C-N 3.29Å; S191-L193 PolarHBondContact O-N 2.87Å; S191-W194 PolarHBondContact O-N 2.75Å; S191-F195 WeakPolarHBondContact O-CD2 3.34Å; S191-F195 PolarHBondContact O-N 2.66Å
192G66.4Low70.4Confident24 Ų2472.1 Ų72.125%0.24737%0.37CS..Hα-helixtrans-60.5-35.7175.800000113.7T188 Q189 A190T188-G192 PolarHBondContact O-N 3.18Å; Q189-G192 PolarHBondContact O-N 3.4Å; A190-G192 VanDerWaalsContact C-N 3.31Å; A190-G192 PolarHBondContact O-N 2.86Å
193L65.6Low71.3Confident14 Ų1468.7 Ų68.77%0.07335%0.354CS..Hα-helixtrans-71.5-41178.3-58.9170.7000111.2F120 Y122 F134 Q189 A190 S191 F195 A196F120-L193 HydrophobicContact CD1-CD1 4.33Å; F120-L193 HydrophobicContact CE1-CD1 3.53Å; F120-L193 HydrophobicContact CZ-CD1 4.13Å; Y122-L193 HydrophobicContact CD1-CB 3.74Å; Y122-L193 VanDerWaalsContact CE1-C 3.47Å; Y122-L193 HydrophobicContact CE1-CB 3.74Å; Y122-L193 WeakPolarHBondContact CE1-O 3.47Å; F134-L193 HydrophobicContact CB-CD2 4.38Å; F134-L193 HydrophobicContact CD1-CD2 3.14Å; F134-L193 HydrophobicContact CD2-CD2 4.2Å; F134-L193 HydrophobicContact CE1-CB 4.48Å; F134-L193 HydrophobicContact CE1-CD2 3.25Å; F134-L193 HydrophobicContact CE1-CG 4.46Å; F134-L193 HydrophobicContact CE2-CD2 4.27Å; F134-L193 HydrophobicContact CG-CD2 3.65Å; F134-L193 HydrophobicContact CZ-CB 4.32Å; F134-L193 HydrophobicContact CZ-CD2 3.83Å; Q189-L193 WeakPolarHBondContact O-CG 3.48Å; Q189-L193 PolarHBondContact O-N 2.91Å; A190-L193 WeakPolarHBondContact O-CB 3.02Å; A190-L193 PolarHBondContact O-N 3.42Å; S191-L193 VanDerWaalsContact C-N 3.29Å; S191-L193 PolarHBondContact O-N 2.87Å; L193-F195 VanDerWaalsContact C-N 3.31Å; L193-F195 PolarHBondContact O-N 2.83Å; L193-A196 WeakPolarHBondContact O-CB 3.08Å; L193-A196 PolarHBondContact O-N 3Å
194W61.1Low72.6Confident130 Ų13064.8 Ų64.849%0.49232%0.324SS..Hα-helixtrans-60-36.6-179-174.9-103.4000113.5Y122 A190 S191 A196 K197Y122-W194 HydrophobicContact CD1-CE3 4.4Å; Y122-W194 HydrophobicContact CD2-CE3 4.49Å; Y122-W194 AromaticContact CG-CE3 3.95Å; Y122-W194 HydrophobicContact CG-CE3 3.95Å; Y122-W194 HydrophobicContact CG-CZ3 4.4Å; A190-W194 PolarHBondContact O-N 2.77Å; S191-W194 PolarHBondContact O-N 2.75Å; W194-A196 PolarHBondContact O-N 2.9Å; W194-K197 HydrophobicContact CZ3-CD 4.4Å; W194-K197 PolarHBondContact O-N 2.85Å
195F62.3Low73.9Confident166 Ų16657 Ų5773%0.72830%0.295SS*.THydrogen-bonded Turntrans-60.7-12.9178.6-71-56.8000114.7S191 L193S191-F195 WeakPolarHBondContact O-CD2 3.34Å; S191-F195 PolarHBondContact O-N 2.66Å; L193-F195 VanDerWaalsContact C-N 3.31Å; L193-F195 PolarHBondContact O-N 2.83Å
196A57.4Low75Confident34 Ų3453.9 Ų53.928%0.28128%0.28SS..THydrogen-bonded Turntrans-88.9-6.8-178.400000114.7F134 L138 L193 W194F134-A196 HydrophobicContact CZ-CB 4.25Å; L138-A196 HydrophobicContact CD1-CB 3.93Å; L138-A196 HydrophobicContact CD2-CB 4.07Å; L193-A196 WeakPolarHBondContact O-CB 3.08Å; L193-A196 PolarHBondContact O-N 3Å; W194-A196 PolarHBondContact O-N 2.9Å
197K61.1Low76.3Confident50 Ų5051.5 Ų51.522%0.21727%0.271CS..SBendtrans-85140.1-174.9-174.4175.5-179.4175.80112.7W194 T199W194-K197 HydrophobicContact CZ3-CD 4.4Å; W194-K197 PolarHBondContact O-N 2.85Å; K197-T199 PolarHBondContact O-N 3.32Å
198K68.1Low77.5Confident104 Ų10447.7 Ų47.745%0.45225%0.247SC..  trans-73123.6172-166.1170.9-175.11780110.8D415K198-D415 HydrophobicContact CD-CB 4.36Å; K198-D415 IonicContact NZ-OD2 3.85Å; K198-D415 PolarHBondContact NZ-OD2 3.39Å
199T80.2Confident78.5Confident50 Ų5048.1 Ų48.131%0.30725%0.25SC..  trans-121166.1174.966.10000110.5K197K197-T199 PolarHBondContact O-N 3.32Å
200F86.2Confident79.6Confident1 Ų145.6 Ų45.60%0.00424%0.238CC..  trans-120.525.5176.5-62.2-85000111.6G202 H203 V273 Q274 L277 D415 M417F200-G202 PolarHBondContact O-N 2.92Å; F200-H203 VanDerWaalsContact CA-CD2 3.41Å; F200-H203 WeakPolarHBondContact CA-CD2 3.09Å; F200-H203 HydrophobicContact CB-CB 4.31Å; F200-H203 WeakPolarHBondContact O-CB 3.18Å; F200-H203 PolarHBondContact O-CD2 3.12Å; F200-H203 PolarHBondContact O-N 2.77Å; F200-V273 HydrophobicContact CB-CB 4.06Å; F200-V273 HydrophobicContact CB-CG1 3.85Å; F200-V273 HydrophobicContact CG-CG1 4.18Å; F200-Q274 HydrophobicContact CB-CB 4.49Å; F200-L277 HydrophobicContact CB-CD1 4.13Å; F200-L277 HydrophobicContact CD2-CD1 3.29Å; F200-L277 HydrophobicContact CE2-CD1 3.98Å; F200-L277 HydrophobicContact CG-CD1 3.99Å; F200-D415 WeakPolarHBondContact CZ-OD1 3.14Å; F200-M417 HydrophobicContact CD1-CG 4.39Å; F200-M417 HydrophobicContact CE1-CB 4.21Å; F200-M417 HydrophobicContact CE1-CG 3.65Å; F200-M417 HydrophobicContact CE2-CG 4.3Å; F200-M417 HydrophobicContact CZ-CB 4Å; F200-M417 HydrophobicContact CZ-CG 3.59Å
201E87.5Confident80.9Confident120 Ų12049.3 Ų49.356%0.56125%0.25SS*.THydrogen-bonded Turntrans-56.6123.8-178.3-72.6177.7-16500110.3H203 Q274E201-H203 PolarHBondContact O-N 3.38Å; E201-Q274 HydrophobicContact CG-CB 4.09Å; E201-Q274 HydrophobicContact CG-CG 3.75Å
202G89.4Confident82.1Confident31 Ų3150 Ų5032%0.3225%0.25SC..THydrogen-bonded Turntrans725.8178.700000115.1F200 D272F200-G202 PolarHBondContact O-N 2.92Å; G202-D272 PolarHBondContact N-OD1 3.32Å
203H94.1Very high83.3Confident23 Ų2355.1 Ų55.111%0.10627%0.267CS..  trans-67.7134.8168.8-76.2-111.1000109.9F200 E201 R246 V247 P248 P249 D272 V273F200-H203 VanDerWaalsContact CA-CD2 3.41Å; F200-H203 WeakPolarHBondContact CA-CD2 3.09Å; F200-H203 HydrophobicContact CB-CB 4.31Å; F200-H203 WeakPolarHBondContact O-CB 3.18Å; F200-H203 PolarHBondContact O-CD2 3.12Å; F200-H203 PolarHBondContact O-N 2.77Å; E201-H203 PolarHBondContact O-N 3.38Å; H203-R246 HydrophobicContact CB-CG 4.3Å; H203-R246 PolarHBondContact CE1-NH1 3.48Å; H203-R246 PolarHBondContact ND1-NH1 2.99Å; H203-V247 WeakPolarHBondContact CA-O 3.19Å; H203-P248 VanDerWaalsContact CE1-CA 3.4Å; H203-P248 WeakPolarHBondContact CE1-CA 3.35Å; H203-P248 WeakPolarHBondContact ND1-CA 3.38Å; H203-P249 WeakPolarHBondContact CD2-CD 3.49Å; H203-P249 WeakPolarHBondContact NE2-CD 3.28Å; H203-D272 WeakPolarHBondContact O-CA 3.46Å; H203-V273 HydrophobicContact CB-CB 4.09Å; H203-V273 HydrophobicContact CB-CG2 4.06Å; H203-V273 WeakPolarHBondContact O-CG2 3.46Å; H203-V273 PolarHBondContact O-N 3Å
204Q96.6Very high84.4Confident30 Ų3060.7 Ų60.714%0.1430%0.296CS..EExtended strand (participates in β ladder)trans-108.6150.3174.4-62.4-159.2-34.600110.9L206 R246 V247 L252 T268 I270 E271Q204-L206 HydrophobicContact CB-CD2 4.2Å; Q204-R246 CarbonylContact O-C 3.56Å; Q204-R246 WeakPolarHBondContact O-CA 3.25Å; Q204-V247 PolarHBondContact N-O 3.47Å; Q204-V247 VanDerWaalsContact N-O 3.16Å; Q204-V247 PolarHBondContact O-N 3.28Å; Q204-L252 HydrophobicContact CB-CD1 3.93Å; Q204-L252 HydrophobicContact CB-CD2 4.43Å; Q204-L252 HydrophobicContact CG-CD1 4.15Å; Q204-L252 HydrophobicContact CG-CD2 3.74Å; Q204-T268 HydrophobicContact CB-CG2 4.42Å; Q204-I270 VanDerWaalsContact CA-O 3.29Å; Q204-I270 WeakPolarHBondContact CA-O 3.46Å; Q204-E271 WeakPolarHBondContact CG-O 3.07Å; Q204-E271 PolarHBondContact NE2-O 3.41Å
205V95.4Very high85.9Confident0 Ų055 Ų550%028%0.275CS..EExtended strand (participates in β ladder)trans-104.9119.4163.6-176.60000108.3W233 D244 V245 R246 M269 I270 V273V205-W233 HydrophobicContact CG1-CD2 4.39Å; V205-W233 HydrophobicContact CG1-CE3 4.12Å; V205-W233 HydrophobicContact CG1-CZ3 4.46Å; V205-W233 HydrophobicContact CG2-CD2 4.32Å; V205-W233 HydrophobicContact CG2-CE3 4.2Å; V205-W233 HydrophobicContact CG2-CH2 3.74Å; V205-W233 HydrophobicContact CG2-CZ2 3.86Å; V205-W233 HydrophobicContact CG2-CZ3 3.92Å; V205-D244 HydrophobicContact CG1-CB 4.47Å; V205-V245 CarbonylContact C-O 3.45Å; V205-V245 WeakPolarHBondContact CA-O 3.36Å; V205-R246 HydrophobicContact CG2-CB 4.11Å; V205-R246 HydrophobicContact CG2-CG 4.38Å; V205-M269 HydrophobicContact CB-CB 4.41Å; V205-M269 HydrophobicContact CG1-CB 4.38Å; V205-M269 HydrophobicContact CG1-SD 4.26Å; V205-M269 WeakPolarHBondContact O-CB 3.31Å; V205-M269 PolarHBondContact O-N 3.41Å; V205-I270 HydrophobicContact CB-CB 3.95Å; V205-I270 HydrophobicContact CB-CD1 4.23Å; V205-I270 HydrophobicContact CB-CG1 4.27Å; V205-I270 HydrophobicContact CG2-CB 4.04Å; V205-I270 HydrophobicContact CG2-CD1 3.92Å; V205-I270 HydrophobicContact CG2-CG1 4.38Å; V205-I270 PolarHBondContact N-O 3.15Å; V205-I270 PolarHBondContact O-N 3.47Å; V205-V273 HydrophobicContact CG2-CG2 3.84Å
206L95.9Very high87Confident0 Ų047.3 Ų47.30%024%0.242CC..EExtended strand (participates in β ladder)trans-102.5137177.8-54.7-173.9000109.8Q204 D244 V245 V247 L252 F255 K256 L259 Y266 S267 T268Q204-L206 HydrophobicContact CB-CD2 4.2Å; L206-D244 WeakPolarHBondContact O-CA 3.38Å; L206-V245 PolarHBondContact N-O 3.34Å; L206-V245 PolarHBondContact O-N 3.07Å; L206-V247 HydrophobicContact CD1-CG2 3.98Å; L206-V247 HydrophobicContact CG-CG2 4.03Å; L206-L252 HydrophobicContact CD1-CD1 4.36Å; L206-F255 HydrophobicContact CD1-CD1 4.04Å; L206-F255 HydrophobicContact CD1-CE1 4.2Å; L206-K256 HydrophobicContact CD1-CG 4.23Å; L206-L259 HydrophobicContact CD1-CD1 4.22Å; L206-Y266 HydrophobicContact CD1-CD2 4.21Å; L206-Y266 HydrophobicContact CD2-CD2 4.4Å; L206-S267 CarbonylContact C-O 3.56Å; L206-S267 WeakPolarHBondContact CA-O 3.46Å; L206-T268 HydrophobicContact CD2-CG2 4.35Å
207R94.3Very high88.3Confident53 Ų5348.5 Ų48.520%0.225%0.252CS..EExtended strand (participates in β ladder)trans-100.6120.5167.5170160-72.7179.5-4.1109.5V209 P242 V243 D244 Y266 S267 M269 T566R207-V209 HydrophobicContact CG-CG2 4.43Å; R207-P242 HydrophobicContact CG-CB 3.84Å; R207-V243 CarbonylContact C-O 3.57Å; R207-V243 WeakPolarHBondContact CA-O 3.23Å; R207-D244 WeakPolarHBondContact CB-OD1 3.41Å; R207-D244 IonicContact CZ-OD1 3.83Å; R207-D244 IonicContact CZ-OD2 2.77Å; R207-D244 IonicContact NE-OD1 3.6Å; R207-D244 PolarHBondContact NE-OD1 2.97Å; R207-D244 IonicContact NE-OD2 3.74Å; R207-D244 IonicContact NH2-OD1 2.78Å; R207-D244 PolarHBondContact NH2-OD1 2.65Å; R207-D244 IonicContact NH2-OD2 2.79Å; R207-D244 PolarHBondContact NH2-OD2 3.34Å; R207-Y266 CarbonylContact O-C 3.58Å; R207-Y266 WeakPolarHBondContact O-CA 3.46Å; R207-S267 PolarHBondContact N-O 3.04Å; R207-S267 PolarHBondContact O-N 3.5Å; R207-M269 HydrophobicContact CB-CG 3.54Å; R207-M269 HydrophobicContact CB-SD 3.64Å; R207-M269 VanDerWaalsContact NH2-CE 3.3Å; R207-T566 PolarHBondContact NH1-O 3.36Å; R207-T566 PolarHBondContact NH2-O 2.85Å
208I94.1Very high89.5Confident0 Ų048 Ų480%025%0.251CS..EExtended strand (participates in β ladder)trans-113.8135.3-177.9-52.3160.3000108.5L219 P242 V243 V245 F255 L259 L264 E265I208-L219 HydrophobicContact CB-CD1 4.4Å; I208-L219 HydrophobicContact CD1-CD2 4.03Å; I208-L219 HydrophobicContact CG2-CD1 3.8Å; I208-L219 HydrophobicContact CG2-CD2 4.1Å; I208-P242 CarbonylContact O-C 3.58Å; I208-P242 WeakPolarHBondContact O-CA 3.14Å; I208-V243 PolarHBondContact N-O 2.88Å; I208-V243 PolarHBondContact O-N 3.25Å; I208-V245 HydrophobicContact CD1-CG2 4.33Å; I208-F255 HydrophobicContact CD1-CE1 4.06Å; I208-F255 HydrophobicContact CD1-CZ 3.92Å; I208-L259 HydrophobicContact CD1-CD1 4.01Å; I208-L259 HydrophobicContact CD1-CD2 3.89Å; I208-L259 HydrophobicContact CG1-CD1 4.09Å; I208-L259 HydrophobicContact CG1-CD2 4.39Å; I208-L259 HydrophobicContact CG2-CD2 4.37Å; I208-L264 HydrophobicContact CG2-CB 4.27Å; I208-L264 HydrophobicContact CG2-CD2 4.07Å; I208-E265 WeakPolarHBondContact CA-O 3.38Å
209V91.8Very high90.2Very high50 Ų5044.1 Ų44.130%0.30324%0.235SC..EExtended strand (participates in β ladder)trans-121.1102.5179.3-174.20000110.1R207 K211 P242 E265R207-V209 HydrophobicContact CG-CG2 4.43Å; V209-K211 PolarHBondContact O-N 2.81Å; V209-P242 HydrophobicContact CG2-CB 4.47Å; V209-E265 PolarHBondContact N-O 3.28Å; V209-E265 VanDerWaalsContact N-O 3.1Å
210P91.4Very high90.1Very high0 Ų047.2 Ų47.20%024%0.244CC..  trans-70.9130.5178.628.3-32.1000110.6Q215 L216 L219 S240 Y241P210-Q215 HydrophobicContact CB-CB 3.89Å; P210-L216 HydrophobicContact CB-CB 4.4Å; P210-L216 HydrophobicContact CB-CD1 4.18Å; P210-L216 HydrophobicContact CG-CD1 3.59Å; P210-L219 HydrophobicContact CB-CD1 4.03Å; P210-L219 HydrophobicContact CG-CD1 4.05Å; P210-S240 WeakPolarHBondContact O-CA 3.38Å; P210-S240 PolarHBondContact O-N 2.88Å; P210-Y241 VanDerWaalsContact CD-O 3.32Å; P210-Y241 WeakPolarHBondContact CD-O 3.37Å
211K93.8Very high89.6Confident102 Ų10249.9 Ų49.944%0.44326%0.259SS..  trans-91.7-15.1-177.6-63176.5179.7173.90114V209 V239 E265V209-K211 PolarHBondContact O-N 2.81Å; K211-V239 VanDerWaalsContact C-CG1 3.4Å; K211-V239 VanDerWaalsContact O-CG1 3.28Å; K211-V239 WeakPolarHBondContact O-CG1 3.26Å; K211-E265 WeakPolarHBondContact CE-OE1 3.19Å; K211-E265 WeakPolarHBondContact CE-OE2 3.44Å; K211-E265 IonicContact NZ-OE1 2.68Å; K211-E265 PolarHBondContact NZ-OE1 3.42Å; K211-E265 IonicContact NZ-OE2 3.73Å; K211-E265 PolarHBondContact NZ-OE2 3.41Å
212N92.3Very high88.4Confident69 Ų6949 Ų4937%0.36925%0.254SS..SBendtrans-153.7170.6-177.95958.2000111.4L214 Q215 L216N212-L214 VanDerWaalsContact C-N 3.27Å; N212-L214 PolarHBondContact O-N 3Å; N212-L214 WeakPolarHBondContact OD1-CB 3.4Å; N212-L214 PolarHBondContact OD1-N 3.08Å; N212-L214 VanDerWaalsContact OD1-N 3.15Å; N212-Q215 PolarHBondContact O-N 2.76Å; N212-Q215 PolarHBondContact OD1-N 2.59Å; N212-L216 PolarHBondContact O-N 2.95Å
213E89.8Confident86.8Confident130 Ų13054.6 Ų54.661%0.60727%0.272SS*.Hα-helixtrans-63.3-29.7-177.8-68.2-62.2156.600113.6L216 A217 V239E213-L216 PolarHBondContact O-N 3Å; E213-L216 WeakPolarHBondContact OE2-CD2 3.38Å; E213-A217 WeakPolarHBondContact O-CB 3.25Å; E213-A217 PolarHBondContact O-N 2.82Å; E213-V239 HydrophobicContact CG-CG2 4.26Å; E213-V239 WeakPolarHBondContact OE1-CG2 3.22Å
214L90.4Very high85.4Confident132 Ų13255.5 Ų55.569%0.69128%0.277SS*.Hα-helixtrans-65.2-49.9176.3-174.9103.9000110.1N212 L216 A217 L218N212-L214 VanDerWaalsContact C-N 3.27Å; N212-L214 PolarHBondContact O-N 3Å; N212-L214 WeakPolarHBondContact OD1-CB 3.4Å; N212-L214 PolarHBondContact OD1-N 3.08Å; N212-L214 VanDerWaalsContact OD1-N 3.15Å; L214-L216 VanDerWaalsContact C-N 3.31Å; L214-L216 PolarHBondContact O-N 3.13Å; L214-A217 WeakPolarHBondContact O-CB 3.14Å; L214-A217 PolarHBondContact O-N 2.78Å; L214-A217 VanDerWaalsContact O-N 3.17Å; L214-L218 WeakPolarHBondContact O-CG 3.49Å; L214-L218 PolarHBondContact O-N 3.28Å
215Q91Very high84.1Confident10 Ų1056.4 Ų56.45%0.04728%0.282CS..Hα-helixtrans-61.1-39.8175.1-77-175.2-10.200112.3P210 N212 A217 L218 L219 H262 D263 L264P210-Q215 HydrophobicContact CB-CB 3.89Å; N212-Q215 PolarHBondContact O-N 2.76Å; N212-Q215 PolarHBondContact OD1-N 2.59Å; Q215-A217 VanDerWaalsContact C-N 3.31Å; Q215-A217 PolarHBondContact O-N 3.22Å; Q215-L218 PolarHBondContact O-N 3.46Å; Q215-L219 WeakPolarHBondContact O-CG 3.33Å; Q215-L219 PolarHBondContact O-N 2.77Å; Q215-H262 PolarHBondContact NE2-O 3.01Å; Q215-H262 VanDerWaalsContact NE2-O 3.16Å; Q215-D263 VanDerWaalsContact NE2-C 3.32Å; Q215-D263 PolarHBondContact NE2-O 3.4Å; Q215-L264 HydrophobicContact CB-CD2 3.62Å; Q215-L264 HydrophobicContact CG-CD2 3.73Å; Q215-L264 HydrophobicContact CG-CG 4.2Å
216L85.9Confident82.9Confident5 Ų560.7 Ų60.73%0.02631%0.308CS..Hα-helixtrans-60.8-41.9174.6-164.275.2000111.8P210 N212 E213 L214 L219 K220 V236 G238 V239P210-L216 HydrophobicContact CB-CB 4.4Å; P210-L216 HydrophobicContact CB-CD1 4.18Å; P210-L216 HydrophobicContact CG-CD1 3.59Å; N212-L216 PolarHBondContact O-N 2.95Å; E213-L216 PolarHBondContact O-N 3Å; E213-L216 WeakPolarHBondContact OE2-CD2 3.38Å; L214-L216 VanDerWaalsContact C-N 3.31Å; L214-L216 PolarHBondContact O-N 3.13Å; L216-L219 PolarHBondContact O-N 2.88Å; L216-K220 WeakPolarHBondContact O-CG 3.3Å; L216-K220 PolarHBondContact O-N 3.03Å; L216-V236 HydrophobicContact CD1-CG1 3.11Å; L216-V236 HydrophobicContact CD2-CG1 4.47Å; L216-V236 HydrophobicContact CG-CG1 3.6Å; L216-G238 WeakPolarHBondContact CD1-O 3.49Å; L216-V239 HydrophobicContact CB-CG2 4.41Å; L216-V239 HydrophobicContact CD2-CG2 4.31Å
217A85.8Confident82.1Confident59 Ų5967.1 Ų67.149%0.48834%0.338SS..Hα-helixtrans-66.7-38177.900000112.2E213 L214 Q215 L219 K220 N221E213-A217 WeakPolarHBondContact O-CB 3.25Å; E213-A217 PolarHBondContact O-N 2.82Å; L214-A217 WeakPolarHBondContact O-CB 3.14Å; L214-A217 PolarHBondContact O-N 2.78Å; L214-A217 VanDerWaalsContact O-N 3.17Å; Q215-A217 VanDerWaalsContact C-N 3.31Å; Q215-A217 PolarHBondContact O-N 3.22Å; A217-L219 VanDerWaalsContact C-N 3.35Å; A217-L219 PolarHBondContact O-N 3.4Å; A217-K220 PolarHBondContact O-N 3.13Å; A217-N221 PolarHBondContact O-N 3.01Å
218L86.4Confident81.5Confident40 Ų4065.1 Ų65.121%0.20933%0.331CS..Hα-helixtrans-59.5-44.6174.1-68.4172.7000111.6L214 Q215 K220 N221 H262L214-L218 WeakPolarHBondContact O-CG 3.49Å; L214-L218 PolarHBondContact O-N 3.28Å; Q215-L218 PolarHBondContact O-N 3.46Å; L218-K220 VanDerWaalsContact C-N 3.26Å; L218-K220 PolarHBondContact O-N 3.14Å; L218-N221 WeakPolarHBondContact O-CB 3.35Å; L218-N221 PolarHBondContact O-N 3.06Å; L218-H262 HydrophobicContact CD1-CB 3.84Å
219L82.6Confident81.1Confident21 Ų2170.8 Ų70.811%0.1136%0.357CS..Hα-helixtrans-71.6-18.5178.6-63.5176000113.8I208 P210 Q215 L216 A217 N221 V236 V243 L259 L264I208-L219 HydrophobicContact CB-CD1 4.4Å; I208-L219 HydrophobicContact CD1-CD2 4.03Å; I208-L219 HydrophobicContact CG2-CD1 3.8Å; I208-L219 HydrophobicContact CG2-CD2 4.1Å; P210-L219 HydrophobicContact CB-CD1 4.03Å; P210-L219 HydrophobicContact CG-CD1 4.05Å; Q215-L219 WeakPolarHBondContact O-CG 3.33Å; Q215-L219 PolarHBondContact O-N 2.77Å; L216-L219 PolarHBondContact O-N 2.88Å; A217-L219 VanDerWaalsContact C-N 3.35Å; A217-L219 PolarHBondContact O-N 3.4Å; L219-N221 VanDerWaalsContact C-N 3.34Å; L219-V236 HydrophobicContact CB-CG2 3.89Å; L219-V243 HydrophobicContact CD1-CB 4.43Å; L219-V243 HydrophobicContact CD1-CG2 4.01Å; L219-L259 HydrophobicContact CD2-CD2 4.46Å; L219-L264 HydrophobicContact CD1-CD2 4.17Å; L219-L264 HydrophobicContact CD2-CD1 4.12Å; L219-L264 HydrophobicContact CG-CD2 4.29Å
220K77.3Confident80.9Confident115 Ų11569.4 Ų69.450%0.535%0.348SS..THydrogen-bonded Turntrans-83.2-10.9174.2-76176.9178.9177.10112.9L216 A217 L218 Q222 V236L216-K220 WeakPolarHBondContact O-CG 3.3Å; L216-K220 PolarHBondContact O-N 3.03Å; A217-K220 PolarHBondContact O-N 3.13Å; L218-K220 VanDerWaalsContact C-N 3.26Å; L218-K220 PolarHBondContact O-N 3.14Å; K220-Q222 PolarHBondContact O-N 3.01Å; K220-Q222 VanDerWaalsContact O-N 3.17Å; K220-V236 HydrophobicContact CD-CG1 4.31Å; K220-V236 HydrophobicContact CG-CB 3.9Å; K220-V236 HydrophobicContact CG-CG1 3.85Å; K220-V236 HydrophobicContact CG-CG2 4.02Å
221N76.5Confident80.8Confident58 Ų5869.9 Ų69.931%0.3135%0.35SS..  trans-69.9113.3-175.8-168.8-5.5000110.7A217 L218 L219 E223 E224 I225A217-N221 PolarHBondContact O-N 3.01Å; L218-N221 WeakPolarHBondContact O-CB 3.35Å; L218-N221 PolarHBondContact O-N 3.06Å; L219-N221 VanDerWaalsContact C-N 3.34Å; N221-E223 VanDerWaalsContact C-N 3.28Å; N221-E223 PolarHBondContact O-N 3.19Å; N221-E223 PolarHBondContact OD1-N 2.99Å; N221-E223 VanDerWaalsContact OD1-N 3.12Å; N221-E224 HydrophobicContact CB-CB 4.49Å; N221-E224 HydrophobicContact CB-CG 3.94Å; N221-E224 PolarHBondContact O-N 3.37Å; N221-I225 PolarHBondContact O-N 2.8Å
222Q61.4Low80.4Confident101 Ų10167.1 Ų67.147%0.47234%0.342SS..Hα-helixtrans-70.1-24.4-178.8-70.3-170.4-10.100113.1K220 I225 V226K220-Q222 PolarHBondContact O-N 3.01Å; K220-Q222 VanDerWaalsContact O-N 3.17Å; Q222-I225 PolarHBondContact O-N 2.82Å; Q222-V226 WeakPolarHBondContact O-CG2 3.42Å; Q222-V226 PolarHBondContact O-N 3.05Å; Q222-V226 VanDerWaalsContact O-N 3.13Å
223E56.8Low80.2Confident149 Ų14964.6 Ų64.670%0.69633%0.327SS*.Hα-helixtrans-64.2-43.9177.1-66-178.916700110.5N221 I225 V226 E227N221-E223 VanDerWaalsContact C-N 3.28Å; N221-E223 PolarHBondContact O-N 3.19Å; N221-E223 PolarHBondContact OD1-N 2.99Å; N221-E223 VanDerWaalsContact OD1-N 3.12Å; E223-I225 VanDerWaalsContact C-N 3.34Å; E223-I225 PolarHBondContact O-N 2.83Å; E223-V226 PolarHBondContact O-N 3.29Å; E223-V226 VanDerWaalsContact O-N 3.16Å; E223-E227 WeakPolarHBondContact O-CB 3.34Å; E223-E227 PolarHBondContact O-N 3.33Å
224E64.6Low79.9Confident42 Ų4259.2 Ų59.220%0.19630%0.302CS..Hα-helixtrans-63.2-38.6176-58.9-67164.700112N221 V226 E227 F228N221-E224 HydrophobicContact CB-CB 4.49Å; N221-E224 HydrophobicContact CB-CG 3.94Å; N221-E224 PolarHBondContact O-N 3.37Å; E224-V226 VanDerWaalsContact C-N 3.27Å; E224-V226 PolarHBondContact O-N 2.8Å; E224-E227 PolarHBondContact O-N 3.42Å; E224-F228 HydrophobicContact CB-CD2 4.43Å; E224-F228 VanDerWaalsContact O-CD2 3.26Å; E224-F228 WeakPolarHBondContact O-CD2 3.31Å; E224-F228 PolarHBondContact O-N 3.37Å; E224-F228 WeakPolarHBondContact OE2-CE2 3.45Å
225I68.5Low79.2Confident49 Ų4953.8 Ų53.825%0.25128%0.278SS..Hα-helixtrans-61.2-40.1176.2-67.8173.6000110.8N221 Q222 E223 E229 L230 V232N221-I225 PolarHBondContact O-N 2.8Å; Q222-I225 PolarHBondContact O-N 2.82Å; E223-I225 VanDerWaalsContact C-N 3.34Å; E223-I225 PolarHBondContact O-N 2.83Å; I225-E229 PolarHBondContact O-N 3.3Å; I225-L230 HydrophobicContact CB-CB 4.49Å; I225-L230 HydrophobicContact CG1-CD1 4.43Å; I225-L230 HydrophobicContact CG2-CB 4.17Å; I225-L230 PolarHBondContact O-N 3.37Å; I225-V232 HydrophobicContact CD1-CG2 4.13Å
226V70.8Confident78.5Confident89 Ų8954.5 Ų54.554%0.53928%0.283SS..Hα-helixtrans-75.1-43.4179.1174.50000111.1Q222 E223 E224 F228 E229Q222-V226 WeakPolarHBondContact O-CG2 3.42Å; Q222-V226 PolarHBondContact O-N 3.05Å; Q222-V226 VanDerWaalsContact O-N 3.13Å; E223-V226 PolarHBondContact O-N 3.29Å; E223-V226 VanDerWaalsContact O-N 3.16Å; E224-V226 VanDerWaalsContact C-N 3.27Å; E224-V226 PolarHBondContact O-N 2.8Å; V226-F228 PolarHBondContact O-N 3.25Å; V226-E229 PolarHBondContact O-N 2.96Å
227E78.6Confident78Confident135 Ų13555.8 Ų55.863%0.63129%0.291SS*.Hα-helixtrans-61-43.5-179.2-178.4170.7175.900112.3E223 E224E223-E227 WeakPolarHBondContact O-CB 3.34Å; E223-E227 PolarHBondContact O-N 3.33Å; E224-E227 PolarHBondContact O-N 3.42Å
228F82.6Confident77.5Confident12 Ų1253.7 Ų53.75%0.05328%0.275CS..THydrogen-bonded Turntrans-89.91.3-180-64.9-60.6000114.2E224 V226 L230 T251 T254 F255 Y258E224-F228 HydrophobicContact CB-CD2 4.43Å; E224-F228 VanDerWaalsContact O-CD2 3.26Å; E224-F228 WeakPolarHBondContact O-CD2 3.31Å; E224-F228 PolarHBondContact O-N 3.37Å; E224-F228 WeakPolarHBondContact OE2-CE2 3.45Å; V226-F228 PolarHBondContact O-N 3.25Å; F228-L230 VanDerWaalsContact C-N 3.28Å; F228-L230 HydrophobicContact CB-CD1 4.16Å; F228-L230 HydrophobicContact CB-CD2 3.56Å; F228-L230 HydrophobicContact CB-CG 3.63Å; F228-L230 PolarHBondContact O-N 3.46Å; F228-T251 PolarHBondContact O-OG1 3.45Å; F228-T254 HydrophobicContact CE1-CG2 3.83Å; F228-F255 HydrophobicContact CB-CD2 4.28Å; F228-F255 HydrophobicContact CD1-CB 4.04Å; F228-F255 HydrophobicContact CD1-CD2 4.29Å; F228-F255 AromaticContact CD2-CD2 3.47Å; F228-F255 HydrophobicContact CD2-CD2 3.47Å; F228-F255 VanDerWaalsContact CD2-CD2 3.47Å; F228-F255 HydrophobicContact CD2-CE2 4.01Å; F228-F255 HydrophobicContact CD2-CG 4.45Å; F228-F255 HydrophobicContact CE1-CB 4.33Å; F228-F255 AromaticContact CE2-CD2 3.75Å; F228-F255 HydrophobicContact CE2-CD2 3.75Å; F228-F255 HydrophobicContact CE2-CE2 4.36Å; F228-F255 HydrophobicContact CG-CB 4.25Å; F228-F255 AromaticContact CG-CD2 3.77Å; F228-F255 HydrophobicContact CG-CD2 3.77Å; F228-F255 HydrophobicContact CG-CG 4.34Å; F228-F255 HydrophobicContact CZ-CD2 4.29Å; F228-Y258 HydrophobicContact CE2-CD1 4.3Å; F228-Y258 HydrophobicContact CE2-CD2 4.33Å; F228-Y258 HydrophobicContact CE2-CG 4.07Å; F228-Y258 HydrophobicContact CZ-CD2 4.41Å; F228-Y258 HydrophobicContact CZ-CG 4.17Å
229E85.5Confident77.4Confident118 Ų11853.6 Ų53.655%0.55128%0.276SS*.THydrogen-bonded Turntrans53.942.8-175.8-59.1-175.2-179.500113I225 V226 P248 H250I225-E229 PolarHBondContact O-N 3.3Å; V226-E229 PolarHBondContact O-N 2.96Å; E229-P248 HydrophobicContact CB-CG 4.03Å; E229-H250 IonicContact OE1-NE2 3.34Å; E229-H250 IonicContact OE2-CE1 3.96Å; E229-H250 PolarHBondContact OE2-CE1 3.48Å; E229-H250 IonicContact OE2-NE2 3.68Å
230L87Confident77.6Confident21 Ų2156.7 Ų56.711%0.1130%0.299CS..  trans-74.5132.7-174.4-58.6-177000111.7I225 F228 V245 V247 F255I225-L230 HydrophobicContact CB-CB 4.49Å; I225-L230 HydrophobicContact CG1-CD1 4.43Å; I225-L230 HydrophobicContact CG2-CB 4.17Å; I225-L230 PolarHBondContact O-N 3.37Å; F228-L230 VanDerWaalsContact C-N 3.28Å; F228-L230 HydrophobicContact CB-CD1 4.16Å; F228-L230 HydrophobicContact CB-CD2 3.56Å; F228-L230 HydrophobicContact CB-CG 3.63Å; F228-L230 PolarHBondContact O-N 3.46Å; L230-V245 HydrophobicContact CB-CG1 3.58Å; L230-V245 HydrophobicContact CD1-CG1 4.09Å; L230-V245 HydrophobicContact CD2-CG1 3.83Å; L230-V245 HydrophobicContact CG-CG1 4Å; L230-V247 HydrophobicContact CD2-CB 4.41Å; L230-V247 HydrophobicContact CD2-CG1 4.04Å; L230-V247 HydrophobicContact CD2-CG2 4.02Å; L230-F255 HydrophobicContact CD1-CD2 4.28Å; L230-F255 HydrophobicContact CD1-CE1 4.38Å; L230-F255 HydrophobicContact CD1-CE2 3.6Å; L230-F255 HydrophobicContact CD1-CZ 3.65Å; L230-F255 HydrophobicContact CD2-CD1 4.23Å; L230-F255 HydrophobicContact CD2-CD2 4.38Å; L230-F255 HydrophobicContact CD2-CE1 4.16Å; L230-F255 HydrophobicContact CD2-CE2 4.34Å; L230-F255 HydrophobicContact CD2-CG 4.32Å; L230-F255 HydrophobicContact CD2-CZ 4.23Å
231D88.4Confident77.9Confident10 Ų1056.1 Ų56.15%0.05330%0.295CS..EExtended strand (participates in β ladder)trans-105.1105.5168.5165.430.5000109.4W233 R246 R363D231-W233 PolarHBondContact O-N 3.01Å; D231-W233 PolarHBondContact OD2-NE1 3.02Å; D231-R246 HydrophobicContact CB-CB 4.16Å; D231-R246 PolarHBondContact N-O 3.11Å; D231-R246 VanDerWaalsContact N-O 3.1Å; D231-R246 PolarHBondContact O-N 2.7Å; D231-R246 IonicContact OD2-CZ 2.63Å; D231-R246 IonicContact OD2-NE 2.86Å; D231-R246 PolarHBondContact OD2-NE 2.88Å; D231-R246 IonicContact OD2-NH2 3.42Å; D231-R246 PolarHBondContact OD2-NH2 2.77Å; D231-R363 IonicContact OD1-CZ 3.08Å; D231-R363 IonicContact OD1-NH1 2.77Å; D231-R363 PolarHBondContact OD1-NH1 2.8Å; D231-R363 IonicContact OD1-NH2 2.59Å; D231-R363 IonicContact OD2-NH1 3.83Å
232V87.1Confident78.5Confident44 Ų4455 Ų5527%0.26729%0.291SS..EExtended strand (participates in β ladder)trans-77.9111.9-176.8-176.90000109.3I225 M234 V245 R363I225-V232 HydrophobicContact CD1-CG2 4.13Å; V232-M234 WeakPolarHBondContact CG1-O 3.28Å; V232-V245 HydrophobicContact CG2-CG2 4.49Å; V232-R363 PolarHBondContact O-NH2 3.28Å
233W87.9Confident79.8Confident17 Ų1750.4 Ų50.46%0.06427%0.27CS..EExtended strand (participates in β ladder)trans-84.6-42.7177.3-74.320.7000111.4V205 D231 D244 R246 I270 M417 Y490 F571 L572V205-W233 HydrophobicContact CG1-CD2 4.39Å; V205-W233 HydrophobicContact CG1-CE3 4.12Å; V205-W233 HydrophobicContact CG1-CZ3 4.46Å; V205-W233 HydrophobicContact CG2-CD2 4.32Å; V205-W233 HydrophobicContact CG2-CE3 4.2Å; V205-W233 HydrophobicContact CG2-CH2 3.74Å; V205-W233 HydrophobicContact CG2-CZ2 3.86Å; V205-W233 HydrophobicContact CG2-CZ3 3.92Å; D231-W233 PolarHBondContact O-N 3.01Å; D231-W233 PolarHBondContact OD2-NE1 3.02Å; W233-D244 HydrophobicContact CB-CB 4.17Å; W233-D244 PolarHBondContact N-O 3Å; W233-R246 HydrophobicContact CZ2-CB 4.45Å; W233-I270 HydrophobicContact CH2-CD1 3.95Å; W233-I270 HydrophobicContact CZ3-CD1 3.77Å; W233-M417 HydrophobicContact CH2-SD 4.34Å; W233-M417 HydrophobicContact CZ2-CE 4.4Å; W233-M417 HydrophobicContact CZ2-SD 3.44Å; W233-M417 WeakPolarHBondContact CZ2-SD 3.23Å; W233-Y490 HydrophobicContact CB-CE1 4.13Å; W233-Y490 VanDerWaalsContact CB-OH 3.3Å; W233-Y490 WeakPolarHBondContact CB-OH 3.32Å; W233-Y490 HydrophobicContact CE3-CE1 4.22Å; W233-F571 HydrophobicContact CB-CE2 3.69Å; W233-F571 HydrophobicContact CB-CZ 4.24Å; W233-F571 AromaticContact CD1-CE2 3.71Å; W233-F571 AromaticContact CD2-CD2 3.65Å; W233-F571 HydrophobicContact CD2-CD2 3.65Å; W233-F571 AromaticContact CD2-CE2 3.66Å; W233-F571 HydrophobicContact CD2-CE2 3.66Å; W233-F571 AromaticContact CE2-CD2 3.82Å; W233-F571 AromaticContact CE3-CD2 3.96Å; W233-F571 HydrophobicContact CE3-CD2 3.96Å; W233-F571 HydrophobicContact CE3-CE2 4.22Å; W233-F571 AromaticContact CG-CD2 3.94Å; W233-F571 HydrophobicContact CG-CD2 3.94Å; W233-F571 AromaticContact CG-CE2 3.42Å; W233-F571 HydrophobicContact CG-CE2 3.42Å; W233-F571 VanDerWaalsContact CG-CE2 3.42Å; W233-F571 HydrophobicContact CG-CZ 4.41Å; W233-F571 HydrophobicContact CZ2-CD2 4.3Å; W233-F571 HydrophobicContact CZ3-CD2 4.4Å; W233-L572 HydrophobicContact CH2-CD1 4.38Å; W233-L572 HydrophobicContact CH2-CG 4.4Å
234M82.4Confident81.5Confident17 Ų1743.3 Ų43.38%0.08424%0.236CC..EExtended strand (participates in β ladder)trans-125.6116.4172.8-173.3179.2-56.200109.3V232 P242 V243 D244 Y490 S491V232-M234 WeakPolarHBondContact CG1-O 3.28Å; M234-P242 HydrophobicContact SD-CG 4.07Å; M234-V243 WeakPolarHBondContact O-CA 3.46Å; M234-V243 VanDerWaalsContact O-CG1 3.32Å; M234-V243 WeakPolarHBondContact O-CG1 3.22Å; M234-D244 HydrophobicContact CB-CB 3.81Å; M234-D244 PolarHBondContact N-O 2.89Å; M234-D244 VanDerWaalsContact N-O 3.08Å; M234-D244 PolarHBondContact O-N 3.39Å; M234-D244 VanDerWaalsContact O-N 3.16Å; M234-Y490 HydrophobicContact CE-CD2 4.23Å; M234-Y490 HydrophobicContact CE-CE2 3.54Å; M234-S491 VanDerWaalsContact CE-OG 3.32Å; M234-S491 WeakPolarHBondContact CE-OG 3.45Å
235G77.2Confident82.8Confident17 Ų1741.6 Ų41.618%0.17523%0.229CC..  trans-73169-174.700000114.6T237G235-T237 WeakPolarHBondContact O-CG2 3.48Å; G235-T237 PolarHBondContact O-N 2.74Å; G235-T237 VanDerWaalsContact O-N 3.15Å
236V75.8Confident84Confident26 Ų2640.3 Ų40.316%0.15822%0.221CC..  trans-71.1108.1-178.5-171.60000111.2L216 L219 K220 V243L216-V236 HydrophobicContact CD1-CG1 3.11Å; L216-V236 HydrophobicContact CD2-CG1 4.47Å; L216-V236 HydrophobicContact CG-CG1 3.6Å; L219-V236 HydrophobicContact CB-CG2 3.89Å; K220-V236 HydrophobicContact CD-CG1 4.31Å; K220-V236 HydrophobicContact CG-CB 3.9Å; K220-V236 HydrophobicContact CG-CG1 3.85Å; K220-V236 HydrophobicContact CG-CG2 4.02Å; V236-V243 HydrophobicContact CB-CG2 4.41Å; V236-V243 HydrophobicContact CG2-CG1 4.27Å; V236-V243 HydrophobicContact CG2-CG2 4.02Å
237T74.1Confident85.1Confident31 Ų3136.1 Ų36.119%0.1920%0.195CC..  trans-93.7-47.7-176.451.20000112.9G235 Y241 I539 Y540G235-T237 WeakPolarHBondContact O-CG2 3.48Å; G235-T237 PolarHBondContact O-N 2.74Å; G235-T237 VanDerWaalsContact O-N 3.15Å; T237-Y241 WeakPolarHBondContact OG1-CB 3.26Å; T237-I539 WeakPolarHBondContact CA-O 3.38Å; T237-I539 WeakPolarHBondContact CB-O 3.48Å; T237-I539 HydrophobicContact CG2-CG1 4.19Å; T237-I539 WeakPolarHBondContact CG2-O 3.48Å; T237-Y540 HydrophobicContact CG2-CD1 4.07Å
238G76.3Confident85.6Confident15 Ų1529.8 Ų29.816%0.15517%0.166CC..SBendtrans176.9176.5-18000000111.4L216 Y241L216-G238 WeakPolarHBondContact CD1-O 3.49Å; G238-Y241 PolarHBondContact O-N 2.91Å
239V85Confident86Confident38 Ų3832.1 Ų32.123%0.2318%0.183CC..THydrogen-bonded Turntrans-58.2141.1173.5176.30000110.1K211 E213 L216 Y241K211-V239 VanDerWaalsContact C-CG1 3.4Å; K211-V239 VanDerWaalsContact O-CG1 3.28Å; K211-V239 WeakPolarHBondContact O-CG1 3.26Å; E213-V239 HydrophobicContact CG-CG2 4.26Å; E213-V239 WeakPolarHBondContact OE1-CG2 3.22Å; L216-V239 HydrophobicContact CB-CG2 4.41Å; L216-V239 HydrophobicContact CD2-CG2 4.31Å; V239-Y241 WeakPolarHBondContact O-CD2 3.31Å; V239-Y241 PolarHBondContact O-N 3.1Å
240S85.5Confident86.2Confident86 Ų8632.5 Ų32.560%0.60118%0.184SC*.THydrogen-bonded Turntrans675.7-178.6-52.60000116.2P210P210-S240 WeakPolarHBondContact O-CA 3.38Å; P210-S240 PolarHBondContact O-N 2.88Å
241Y84.3Confident86.4Confident103 Ų10332.2 Ų32.240%0.40418%0.183SC..SBendtrans-101.5141.6172.4-70.4-84000110.9P210 T237 G238 V239P210-Y241 VanDerWaalsContact CD-O 3.32Å; P210-Y241 WeakPolarHBondContact CD-O 3.37Å; T237-Y241 WeakPolarHBondContact OG1-CB 3.26Å; G238-Y241 PolarHBondContact O-N 2.91Å; V239-Y241 WeakPolarHBondContact O-CD2 3.31Å; V239-Y241 PolarHBondContact O-N 3.1Å
242P88.7Confident86.6Confident35 Ų3532.4 Ų32.423%0.22718%0.184CC..  trans-67.8148.2-176.428.4-34.5000112.4R207 I208 V209 M234R207-P242 HydrophobicContact CG-CB 3.84Å; I208-P242 CarbonylContact O-C 3.58Å; I208-P242 WeakPolarHBondContact O-CA 3.14Å; V209-P242 HydrophobicContact CG2-CB 4.47Å; M234-P242 HydrophobicContact SD-CG 4.07Å
243V89.4Confident86.9Confident4 Ų435.9 Ų35.92%0.02420%0.197CC..EExtended strand (participates in β ladder)trans-120.8123.3168.5-176.80000106.6R207 I208 L219 M234 V236 V245R207-V243 CarbonylContact C-O 3.57Å; R207-V243 WeakPolarHBondContact CA-O 3.23Å; I208-V243 PolarHBondContact N-O 2.88Å; I208-V243 PolarHBondContact O-N 3.25Å; L219-V243 HydrophobicContact CD1-CB 4.43Å; L219-V243 HydrophobicContact CD1-CG2 4.01Å; M234-V243 WeakPolarHBondContact O-CA 3.46Å; M234-V243 VanDerWaalsContact O-CG1 3.32Å; M234-V243 WeakPolarHBondContact O-CG1 3.22Å; V236-V243 HydrophobicContact CB-CG2 4.41Å; V236-V243 HydrophobicContact CG2-CG1 4.27Å; V236-V243 HydrophobicContact CG2-CG2 4.02Å; V243-V245 HydrophobicContact CG1-CG2 3.89Å
244D91.2Very high87.2Confident0 Ų039.2 Ų39.20%022%0.22CC..EExtended strand (participates in β ladder)trans-108.8125.4-177.5-60.3-21.5000108.7V205 L206 R207 W233 M234 M269 Y490V205-D244 HydrophobicContact CG1-CB 4.47Å; L206-D244 WeakPolarHBondContact O-CA 3.38Å; R207-D244 WeakPolarHBondContact CB-OD1 3.41Å; R207-D244 IonicContact CZ-OD1 3.83Å; R207-D244 IonicContact CZ-OD2 2.77Å; R207-D244 IonicContact NE-OD1 3.6Å; R207-D244 PolarHBondContact NE-OD1 2.97Å; R207-D244 IonicContact NE-OD2 3.74Å; R207-D244 IonicContact NH2-OD1 2.78Å; R207-D244 PolarHBondContact NH2-OD1 2.65Å; R207-D244 IonicContact NH2-OD2 2.79Å; R207-D244 PolarHBondContact NH2-OD2 3.34Å; W233-D244 HydrophobicContact CB-CB 4.17Å; W233-D244 PolarHBondContact N-O 3Å; M234-D244 HydrophobicContact CB-CB 3.81Å; M234-D244 PolarHBondContact N-O 2.89Å; M234-D244 VanDerWaalsContact N-O 3.08Å; M234-D244 PolarHBondContact O-N 3.39Å; M234-D244 VanDerWaalsContact O-N 3.16Å; D244-M269 HydrophobicContact CB-SD 4.19Å; D244-M269 VanDerWaalsContact CG-SD 3.51Å; D244-M269 VanDerWaalsContact OD1-SD 3.39Å; D244-Y490 WeakPolarHBondContact CB-OH 3.42Å; D244-Y490 PolarHBondContact OD2-OH 3.19Å; D244-Y490 VanDerWaalsContact OD2-OH 3.1Å
245V92.8Very high87.7Confident6 Ų638.7 Ų38.74%0.03622%0.217CC..EExtended strand (participates in β ladder)trans-135.5126.9-172.9-174.10000110.3V205 L206 I208 L230 V232 V243 V247V205-V245 CarbonylContact C-O 3.45Å; V205-V245 WeakPolarHBondContact CA-O 3.36Å; L206-V245 PolarHBondContact N-O 3.34Å; L206-V245 PolarHBondContact O-N 3.07Å; I208-V245 HydrophobicContact CD1-CG2 4.33Å; L230-V245 HydrophobicContact CB-CG1 3.58Å; L230-V245 HydrophobicContact CD1-CG1 4.09Å; L230-V245 HydrophobicContact CD2-CG1 3.83Å; L230-V245 HydrophobicContact CG-CG1 4Å; V232-V245 HydrophobicContact CG2-CG2 4.49Å; V243-V245 HydrophobicContact CG1-CG2 3.89Å; V245-V247 HydrophobicContact CG1-CG2 4.32Å
246R94.1Very high88.6Confident23 Ų2339.1 Ų39.19%0.08721%0.214CC..EExtended strand (participates in β ladder)trans-81.7126.4168-179-17365.585.110.4109.5H203 Q204 V205 D231 W233 V273H203-R246 HydrophobicContact CB-CG 4.3Å; H203-R246 PolarHBondContact CE1-NH1 3.48Å; H203-R246 PolarHBondContact ND1-NH1 2.99Å; Q204-R246 CarbonylContact O-C 3.56Å; Q204-R246 WeakPolarHBondContact O-CA 3.25Å; V205-R246 HydrophobicContact CG2-CB 4.11Å; V205-R246 HydrophobicContact CG2-CG 4.38Å; D231-R246 HydrophobicContact CB-CB 4.16Å; D231-R246 PolarHBondContact N-O 3.11Å; D231-R246 VanDerWaalsContact N-O 3.1Å; D231-R246 PolarHBondContact O-N 2.7Å; D231-R246 IonicContact OD2-CZ 2.63Å; D231-R246 IonicContact OD2-NE 2.86Å; D231-R246 PolarHBondContact OD2-NE 2.88Å; D231-R246 IonicContact OD2-NH2 3.42Å; D231-R246 PolarHBondContact OD2-NH2 2.77Å; W233-R246 HydrophobicContact CZ2-CB 4.45Å; R246-V273 HydrophobicContact CG-CG2 4.34Å
247V94.3Very high89.5Confident0 Ų041.3 Ų41.30%023%0.23CC..EExtended strand (participates in β ladder)trans-117.4127.5-175.8-166.20000109.4H203 Q204 L206 L230 V245 L252 F255H203-V247 WeakPolarHBondContact CA-O 3.19Å; Q204-V247 PolarHBondContact N-O 3.47Å; Q204-V247 VanDerWaalsContact N-O 3.16Å; Q204-V247 PolarHBondContact O-N 3.28Å; L206-V247 HydrophobicContact CD1-CG2 3.98Å; L206-V247 HydrophobicContact CG-CG2 4.03Å; L230-V247 HydrophobicContact CD2-CB 4.41Å; L230-V247 HydrophobicContact CD2-CG1 4.04Å; L230-V247 HydrophobicContact CD2-CG2 4.02Å; V245-V247 HydrophobicContact CG1-CG2 4.32Å; V247-L252 HydrophobicContact CB-CD1 3.99Å; V247-L252 HydrophobicContact CG1-CB 4.39Å; V247-L252 HydrophobicContact CG1-CD1 4.08Å; V247-F255 HydrophobicContact CB-CD1 4.49Å; V247-F255 HydrophobicContact CG1-CB 4.14Å; V247-F255 HydrophobicContact CG1-CD1 3.99Å; V247-F255 HydrophobicContact CG1-CG 4.35Å; V247-F255 HydrophobicContact CG2-CD1 3.66Å; V247-F255 HydrophobicContact CG2-CE1 3.86Å
248P88.9Confident90.4Very high3 Ų341.2 Ų41.22%0.01923%0.227CC..  trans-62.3148.7172-22.833.6000114.2H203 E229 H250 T251 L252H203-P248 VanDerWaalsContact CE1-CA 3.4Å; H203-P248 WeakPolarHBondContact CE1-CA 3.35Å; H203-P248 WeakPolarHBondContact ND1-CA 3.38Å; E229-P248 HydrophobicContact CB-CG 4.03Å; P248-H250 VanDerWaalsContact CB-CE1 3.41Å; P248-H250 WeakPolarHBondContact CB-CE1 3.45Å; P248-H250 WeakPolarHBondContact CB-ND1 3.38Å; P248-H250 PolarHBondContact O-N 2.91Å; P248-T251 WeakPolarHBondContact CD-OG1 3.4Å; P248-T251 PolarHBondContact O-N 2.87Å; P248-T251 VanDerWaalsContact O-N 3.17Å; P248-T251 PolarHBondContact O-OG1 2.89Å; P248-L252 WeakPolarHBondContact O-CB 3.3Å; P248-L252 PolarHBondContact O-N 2.91Å
249P91.1Very high91.3Very high61 Ų6140.5 Ų40.540%0.39622%0.219SC..Hα-helixtrans-60.6-32.2-177.824.7-36.2000112.8H203H203-P249 WeakPolarHBondContact CD2-CD 3.49Å; H203-P249 WeakPolarHBondContact NE2-CD 3.28Å
250H88.2Confident91.8Very high126 Ų12643 Ų4358%0.58323%0.232SC*.Hα-helixtrans-76.2-20.3-177.469.7-88.1000113.6E229 P248E229-H250 IonicContact OE1-NE2 3.34Å; E229-H250 IonicContact OE2-CE1 3.96Å; E229-H250 PolarHBondContact OE2-CE1 3.48Å; E229-H250 IonicContact OE2-NE2 3.68Å; P248-H250 VanDerWaalsContact CB-CE1 3.41Å; P248-H250 WeakPolarHBondContact CB-CE1 3.45Å; P248-H250 WeakPolarHBondContact CB-ND1 3.38Å; P248-H250 PolarHBondContact O-N 2.91Å
251T91.4Very high92.2Very high14 Ų1442.9 Ų42.99%0.08623%0.23CC..Hα-helixtrans-106.1-9.917452.90000113.3F228 P248 E253 T254 F255F228-T251 PolarHBondContact O-OG1 3.45Å; P248-T251 WeakPolarHBondContact CD-OG1 3.4Å; P248-T251 PolarHBondContact O-N 2.87Å; P248-T251 VanDerWaalsContact O-N 3.17Å; P248-T251 PolarHBondContact O-OG1 2.89Å; T251-E253 PolarHBondContact O-N 2.96Å; T251-T254 PolarHBondContact O-N 2.76Å; T251-F255 WeakPolarHBondContact O-CB 3.3Å; T251-F255 PolarHBondContact O-N 2.95Å
252L92.3Very high92.6Very high14 Ų1441.1 Ų41.17%0.07323%0.226CC..Hα-helixtrans-53.2-53.8-170.8-178.263.5000114.1Q204 L206 V247 P248 F255 K256Q204-L252 HydrophobicContact CB-CD1 3.93Å; Q204-L252 HydrophobicContact CB-CD2 4.43Å; Q204-L252 HydrophobicContact CG-CD1 4.15Å; Q204-L252 HydrophobicContact CG-CD2 3.74Å; L206-L252 HydrophobicContact CD1-CD1 4.36Å; V247-L252 HydrophobicContact CB-CD1 3.99Å; V247-L252 HydrophobicContact CG1-CB 4.39Å; V247-L252 HydrophobicContact CG1-CD1 4.08Å; P248-L252 WeakPolarHBondContact O-CB 3.3Å; P248-L252 PolarHBondContact O-N 2.91Å; L252-F255 PolarHBondContact O-N 2.62Å; L252-K256 HydrophobicContact CD1-CD 4.5Å; L252-K256 HydrophobicContact CG-CD 4.45Å; L252-K256 WeakPolarHBondContact O-CG 3.19Å; L252-K256 PolarHBondContact O-N 3.45Å
253E93.9Very high92.8Very high117 Ų11745.6 Ų45.655%0.54725%0.248SC..Hα-helixtrans-71.9-34.2-175.4-65.2-57121.800112.2T251 K256 S257T251-E253 PolarHBondContact O-N 2.96Å; E253-K256 IonicContact OE1-NZ 3.44Å; E253-K256 PolarHBondContact OE1-NZ 3.42Å; E253-K256 VanDerWaalsContact OE1-NZ 3.14Å; E253-S257 WeakPolarHBondContact O-CB 3.46Å; E253-S257 PolarHBondContact O-N 3.47Å; E253-S257 PolarHBondContact O-OG 3.34Å
254T93.8Very high93Very high88 Ų8845.5 Ų45.554%0.5425%0.247SC..Hα-helixtrans-65.3-42.9172.8-48.40000110.7F228 T251 S257 Y258F228-T254 HydrophobicContact CE1-CG2 3.83Å; T251-T254 PolarHBondContact O-N 2.76Å; T254-S257 WeakPolarHBondContact O-CB 3.36Å; T254-S257 PolarHBondContact O-N 3.2Å; T254-Y258 PolarHBondContact O-N 3.06Å
255F94.3Very high93.1Very high5 Ų551 Ų512%0.02227%0.273CS..Hα-helixtrans-67.5-42.4178.4-175.8-120.1000111.9L206 I208 F228 L230 V247 T251 L252 S257 Y258 L259L206-F255 HydrophobicContact CD1-CD1 4.04Å; L206-F255 HydrophobicContact CD1-CE1 4.2Å; I208-F255 HydrophobicContact CD1-CE1 4.06Å; I208-F255 HydrophobicContact CD1-CZ 3.92Å; F228-F255 HydrophobicContact CB-CD2 4.28Å; F228-F255 HydrophobicContact CD1-CB 4.04Å; F228-F255 HydrophobicContact CD1-CD2 4.29Å; F228-F255 AromaticContact CD2-CD2 3.47Å; F228-F255 HydrophobicContact CD2-CD2 3.47Å; F228-F255 VanDerWaalsContact CD2-CD2 3.47Å; F228-F255 HydrophobicContact CD2-CE2 4.01Å; F228-F255 HydrophobicContact CD2-CG 4.45Å; F228-F255 HydrophobicContact CE1-CB 4.33Å; F228-F255 AromaticContact CE2-CD2 3.75Å; F228-F255 HydrophobicContact CE2-CD2 3.75Å; F228-F255 HydrophobicContact CE2-CE2 4.36Å; F228-F255 HydrophobicContact CG-CB 4.25Å; F228-F255 AromaticContact CG-CD2 3.77Å; F228-F255 HydrophobicContact CG-CD2 3.77Å; F228-F255 HydrophobicContact CG-CG 4.34Å; F228-F255 HydrophobicContact CZ-CD2 4.29Å; L230-F255 HydrophobicContact CD1-CD2 4.28Å; L230-F255 HydrophobicContact CD1-CE1 4.38Å; L230-F255 HydrophobicContact CD1-CE2 3.6Å; L230-F255 HydrophobicContact CD1-CZ 3.65Å; L230-F255 HydrophobicContact CD2-CD1 4.23Å; L230-F255 HydrophobicContact CD2-CD2 4.38Å; L230-F255 HydrophobicContact CD2-CE1 4.16Å; L230-F255 HydrophobicContact CD2-CE2 4.34Å; L230-F255 HydrophobicContact CD2-CG 4.32Å; L230-F255 HydrophobicContact CD2-CZ 4.23Å; V247-F255 HydrophobicContact CB-CD1 4.49Å; V247-F255 HydrophobicContact CG1-CB 4.14Å; V247-F255 HydrophobicContact CG1-CD1 3.99Å; V247-F255 HydrophobicContact CG1-CG 4.35Å; V247-F255 HydrophobicContact CG2-CD1 3.66Å; V247-F255 HydrophobicContact CG2-CE1 3.86Å; T251-F255 WeakPolarHBondContact O-CB 3.3Å; T251-F255 PolarHBondContact O-N 2.95Å; L252-F255 PolarHBondContact O-N 2.62Å; F255-S257 VanDerWaalsContact C-N 3.31Å; F255-S257 PolarHBondContact O-N 3.29Å; F255-Y258 HydrophobicContact CD2-CD1 4.2Å; F255-Y258 HydrophobicContact CE2-CD1 4.11Å; F255-Y258 WeakPolarHBondContact O-CB 3.45Å; F255-Y258 PolarHBondContact O-N 2.92Å; F255-Y258 VanDerWaalsContact O-N 3.13Å; F255-L259 HydrophobicContact CD1-CD1 4.1Å; F255-L259 HydrophobicContact CD1-CG 4.49Å; F255-L259 HydrophobicContact CE1-CD1 3.78Å; F255-L259 HydrophobicContact CE1-CD2 4.39Å; F255-L259 HydrophobicContact CE1-CG 4.23Å; F255-L259 HydrophobicContact CE2-CD2 4.19Å; F255-L259 HydrophobicContact CE2-CG 4.4Å; F255-L259 HydrophobicContact CZ-CD1 4.17Å; F255-L259 HydrophobicContact CZ-CD2 3.92Å; F255-L259 HydrophobicContact CZ-CG 4.18Å; F255-L259 WeakPolarHBondContact O-CG 3.32Å; F255-L259 PolarHBondContact O-N 3.38Å
256K95.1Very high93.2Very high27 Ų2754 Ų5412%0.11728%0.284CS..Hα-helixtrans-57.3-45.1171.8-76.3179.3-175.3161.90111.9L206 L252 E253 Y258 L259 D260 Y266L206-K256 HydrophobicContact CD1-CG 4.23Å; L252-K256 HydrophobicContact CD1-CD 4.5Å; L252-K256 HydrophobicContact CG-CD 4.45Å; L252-K256 WeakPolarHBondContact O-CG 3.19Å; L252-K256 PolarHBondContact O-N 3.45Å; E253-K256 IonicContact OE1-NZ 3.44Å; E253-K256 PolarHBondContact OE1-NZ 3.42Å; E253-K256 VanDerWaalsContact OE1-NZ 3.14Å; K256-Y258 VanDerWaalsContact C-N 3.3Å; K256-Y258 PolarHBondContact O-N 3.02Å; K256-L259 WeakPolarHBondContact O-CB 3.37Å; K256-L259 PolarHBondContact O-N 3.2Å; K256-L259 VanDerWaalsContact O-N 3.15Å; K256-D260 VanDerWaalsContact O-CG 3.3Å; K256-D260 PolarHBondContact O-N 3.42Å; K256-Y266 WeakPolarHBondContact CB-OH 3.25Å; K256-Y266 HydrophobicContact CD-CE2 4.11Å; K256-Y266 HydrophobicContact CG-CE2 3.8Å
257S94.9Very high93.3Very high71 Ų7155.9 Ų55.950%0.49730%0.301SS..Hα-helixtrans-61.6-38.4175.9-580000112.2E253 T254 F255 D260 S261E253-S257 WeakPolarHBondContact O-CB 3.46Å; E253-S257 PolarHBondContact O-N 3.47Å; E253-S257 PolarHBondContact O-OG 3.34Å; T254-S257 WeakPolarHBondContact O-CB 3.36Å; T254-S257 PolarHBondContact O-N 3.2Å; F255-S257 VanDerWaalsContact C-N 3.31Å; F255-S257 PolarHBondContact O-N 3.29Å; S257-D260 PolarHBondContact O-N 3.02Å; S257-S261 WeakPolarHBondContact O-CB 3.31Å; S257-S261 PolarHBondContact O-N 2.98Å; S257-S261 PolarHBondContact O-OG 2.92Å
258Y93.3Very high93.3Very high30 Ų3058.7 Ų58.712%0.11832%0.318CS..Hα-helixtrans-62.1-46.2173.2168.7-91000111.3F228 T254 F255 K256 S261 H262F228-Y258 HydrophobicContact CE2-CD1 4.3Å; F228-Y258 HydrophobicContact CE2-CD2 4.33Å; F228-Y258 HydrophobicContact CE2-CG 4.07Å; F228-Y258 HydrophobicContact CZ-CD2 4.41Å; F228-Y258 HydrophobicContact CZ-CG 4.17Å; T254-Y258 PolarHBondContact O-N 3.06Å; F255-Y258 HydrophobicContact CD2-CD1 4.2Å; F255-Y258 HydrophobicContact CE2-CD1 4.11Å; F255-Y258 WeakPolarHBondContact O-CB 3.45Å; F255-Y258 PolarHBondContact O-N 2.92Å; F255-Y258 VanDerWaalsContact O-N 3.13Å; K256-Y258 VanDerWaalsContact C-N 3.3Å; K256-Y258 PolarHBondContact O-N 3.02Å; Y258-S261 PolarHBondContact O-N 2.85Å; Y258-S261 PolarHBondContact O-OG 2.61Å; Y258-H262 AromaticContact CD2-CE1 3.5Å; Y258-H262 VanDerWaalsContact CD2-CE1 3.5Å; Y258-H262 WeakPolarHBondContact CD2-CE1 3.33Å; Y258-H262 AromaticContact CD2-ND1 3.64Å; Y258-H262 AromaticContact CE2-CE1 3.22Å; Y258-H262 WeakPolarHBondContact CE2-CE1 3.42Å; Y258-H262 AromaticContact CE2-ND1 3.53Å; Y258-H262 AromaticContact CZ-CE1 3.86Å; Y258-H262 AromaticContact CZ-ND1 3.81Å; Y258-H262 PolarHBondContact O-N 3.4Å; Y258-H262 PolarHBondContact O-ND1 2.84Å
259L94.1Very high93.5Very high0 Ų060.7 Ų60.70%033%0.328CS..Hα-helixtrans-60.2-47.3176.5-63.7175.6000111.1L206 I208 L219 F255 K256 S261 H262 D263 L264 Y266L206-L259 HydrophobicContact CD1-CD1 4.22Å; I208-L259 HydrophobicContact CD1-CD1 4.01Å; I208-L259 HydrophobicContact CD1-CD2 3.89Å; I208-L259 HydrophobicContact CG1-CD1 4.09Å; I208-L259 HydrophobicContact CG1-CD2 4.39Å; I208-L259 HydrophobicContact CG2-CD2 4.37Å; L219-L259 HydrophobicContact CD2-CD2 4.46Å; F255-L259 HydrophobicContact CD1-CD1 4.1Å; F255-L259 HydrophobicContact CD1-CG 4.49Å; F255-L259 HydrophobicContact CE1-CD1 3.78Å; F255-L259 HydrophobicContact CE1-CD2 4.39Å; F255-L259 HydrophobicContact CE1-CG 4.23Å; F255-L259 HydrophobicContact CE2-CD2 4.19Å; F255-L259 HydrophobicContact CE2-CG 4.4Å; F255-L259 HydrophobicContact CZ-CD1 4.17Å; F255-L259 HydrophobicContact CZ-CD2 3.92Å; F255-L259 HydrophobicContact CZ-CG 4.18Å; F255-L259 WeakPolarHBondContact O-CG 3.32Å; F255-L259 PolarHBondContact O-N 3.38Å; K256-L259 WeakPolarHBondContact O-CB 3.37Å; K256-L259 PolarHBondContact O-N 3.2Å; K256-L259 VanDerWaalsContact O-N 3.15Å; L259-S261 VanDerWaalsContact C-N 3.35Å; L259-S261 PolarHBondContact O-N 3.28Å; L259-H262 CarbonylContact O-C 3.6Å; L259-H262 PolarHBondContact O-N 3.07Å; L259-H262 VanDerWaalsContact O-N 3.16Å; L259-D263 PolarHBondContact O-N 3.33Å; L259-L264 HydrophobicContact CB-CB 4.06Å; L259-L264 HydrophobicContact CD2-CB 3.89Å; L259-L264 HydrophobicContact CD2-CD1 3.62Å; L259-L264 HydrophobicContact CD2-CG 4.38Å; L259-L264 WeakPolarHBondContact O-CB 3.46Å; L259-L264 PolarHBondContact O-N 3.19Å; L259-Y266 HydrophobicContact CB-CD1 3.69Å; L259-Y266 HydrophobicContact CB-CE1 3.88Å; L259-Y266 HydrophobicContact CD1-CD1 3.51Å; L259-Y266 HydrophobicContact CD1-CD2 4.46Å; L259-Y266 HydrophobicContact CD1-CE1 4.11Å; L259-Y266 HydrophobicContact CD1-CG 3.72Å; L259-Y266 HydrophobicContact CG-CD1 4.25Å
260D95.5Very high93.5Very high91 Ų9158.1 Ų58.149%0.48731%0.31SS..Hα-helixtrans-60.9-41.4178.5-69.2-33.2000111.8K256 S257 H262 D263 Y266K256-D260 VanDerWaalsContact O-CG 3.3Å; K256-D260 PolarHBondContact O-N 3.42Å; S257-D260 PolarHBondContact O-N 3.02Å; D260-H262 PolarHBondContact O-N 2.71Å; D260-D263 PolarHBondContact O-N 2.82Å; D260-Y266 WeakPolarHBondContact OD1-CE1 3.38Å
261S94.6Very high93.8Very high82 Ų8259.6 Ų59.657%0.57332%0.317SS*.Hα-helixtrans-67.5-17.317972.50000114.6S257 Y258 L259S257-S261 WeakPolarHBondContact O-CB 3.31Å; S257-S261 PolarHBondContact O-N 2.98Å; S257-S261 PolarHBondContact O-OG 2.92Å; Y258-S261 PolarHBondContact O-N 2.85Å; Y258-S261 PolarHBondContact O-OG 2.61Å; L259-S261 VanDerWaalsContact C-N 3.35Å; L259-S261 PolarHBondContact O-N 3.28Å
262H92.3Very high93.8Very high67 Ų6761.6 Ų61.631%0.3133%0.328SS..THydrogen-bonded Turntrans-109.513179.4-66.197.9000112.7Q215 L218 Y258 L259 D260 L264Q215-H262 PolarHBondContact NE2-O 3.01Å; Q215-H262 VanDerWaalsContact NE2-O 3.16Å; L218-H262 HydrophobicContact CD1-CB 3.84Å; Y258-H262 AromaticContact CD2-CE1 3.5Å; Y258-H262 VanDerWaalsContact CD2-CE1 3.5Å; Y258-H262 WeakPolarHBondContact CD2-CE1 3.33Å; Y258-H262 AromaticContact CD2-ND1 3.64Å; Y258-H262 AromaticContact CE2-CE1 3.22Å; Y258-H262 WeakPolarHBondContact CE2-CE1 3.42Å; Y258-H262 AromaticContact CE2-ND1 3.53Å; Y258-H262 AromaticContact CZ-CE1 3.86Å; Y258-H262 AromaticContact CZ-ND1 3.81Å; Y258-H262 PolarHBondContact O-N 3.4Å; Y258-H262 PolarHBondContact O-ND1 2.84Å; L259-H262 CarbonylContact O-C 3.6Å; L259-H262 PolarHBondContact O-N 3.07Å; L259-H262 VanDerWaalsContact O-N 3.16Å; D260-H262 PolarHBondContact O-N 2.71Å; H262-L264 HydrophobicContact CB-CD1 4.08Å; H262-L264 HydrophobicContact CB-CG 4.28Å; H262-L264 PolarHBondContact O-N 2.96Å; H262-L264 VanDerWaalsContact O-N 3.15Å
263D94.3Very high93.7Very high128 Ų12861 Ų6168%0.68432%0.324SS*.THydrogen-bonded Turntrans53.130.7-176.4-62.1-43.5000113.1Q215 L259 D260 E265Q215-D263 VanDerWaalsContact NE2-C 3.32Å; Q215-D263 PolarHBondContact NE2-O 3.4Å; L259-D263 PolarHBondContact O-N 3.33Å; D260-D263 PolarHBondContact O-N 2.82Å; D263-E265 PolarHBondContact O-N 3.38Å
264L93.3Very high93.5Very high3 Ų355.8 Ų55.82%0.01630%0.3CS..  trans-82.5108.5176.6-78.9164000109I208 Q215 L219 L259 H262 Y266I208-L264 HydrophobicContact CG2-CB 4.27Å; I208-L264 HydrophobicContact CG2-CD2 4.07Å; Q215-L264 HydrophobicContact CB-CD2 3.62Å; Q215-L264 HydrophobicContact CG-CD2 3.73Å; Q215-L264 HydrophobicContact CG-CG 4.2Å; L219-L264 HydrophobicContact CD1-CD2 4.17Å; L219-L264 HydrophobicContact CD2-CD1 4.12Å; L219-L264 HydrophobicContact CG-CD2 4.29Å; L259-L264 HydrophobicContact CB-CB 4.06Å; L259-L264 HydrophobicContact CD2-CB 3.89Å; L259-L264 HydrophobicContact CD2-CD1 3.62Å; L259-L264 HydrophobicContact CD2-CG 4.38Å; L259-L264 WeakPolarHBondContact O-CB 3.46Å; L259-L264 PolarHBondContact O-N 3.19Å; H262-L264 HydrophobicContact CB-CD1 4.08Å; H262-L264 HydrophobicContact CB-CG 4.28Å; H262-L264 PolarHBondContact O-N 2.96Å; H262-L264 VanDerWaalsContact O-N 3.15Å; L264-Y266 PolarHBondContact O-N 3.08Å
265E93.1Very high93.3Very high115 Ų11553.7 Ų53.754%0.53729%0.292SS..EExtended strand (participates in β ladder)trans-69.2131.8174.6-76-179.1178.400110.9I208 V209 K211 D263I208-E265 WeakPolarHBondContact CA-O 3.38Å; V209-E265 PolarHBondContact N-O 3.28Å; V209-E265 VanDerWaalsContact N-O 3.1Å; K211-E265 WeakPolarHBondContact CE-OE1 3.19Å; K211-E265 WeakPolarHBondContact CE-OE2 3.44Å; K211-E265 IonicContact NZ-OE1 2.68Å; K211-E265 PolarHBondContact NZ-OE1 3.42Å; K211-E265 IonicContact NZ-OE2 3.73Å; K211-E265 PolarHBondContact NZ-OE2 3.41Å; D263-E265 PolarHBondContact O-N 3.38Å
266Y94.9Very high93Very high70 Ų7054.8 Ų54.828%0.27530%0.298SS..EExtended strand (participates in β ladder)trans-136.3161.6175.166.9-87.5000112.4L206 R207 K256 L259 D260 L264L206-Y266 HydrophobicContact CD1-CD2 4.21Å; L206-Y266 HydrophobicContact CD2-CD2 4.4Å; R207-Y266 CarbonylContact O-C 3.58Å; R207-Y266 WeakPolarHBondContact O-CA 3.46Å; K256-Y266 WeakPolarHBondContact CB-OH 3.25Å; K256-Y266 HydrophobicContact CD-CE2 4.11Å; K256-Y266 HydrophobicContact CG-CE2 3.8Å; L259-Y266 HydrophobicContact CB-CD1 3.69Å; L259-Y266 HydrophobicContact CB-CE1 3.88Å; L259-Y266 HydrophobicContact CD1-CD1 3.51Å; L259-Y266 HydrophobicContact CD1-CD2 4.46Å; L259-Y266 HydrophobicContact CD1-CE1 4.11Å; L259-Y266 HydrophobicContact CD1-CG 3.72Å; L259-Y266 HydrophobicContact CG-CD1 4.25Å; D260-Y266 WeakPolarHBondContact OD1-CE1 3.38Å; L264-Y266 PolarHBondContact O-N 3.08Å
267S95.5Very high92.6Very high62 Ų6253.5 Ų53.543%0.43429%0.292SS..EExtended strand (participates in β ladder)trans-137.5146.8171.555.80000109.8L206 R207 M269L206-S267 CarbonylContact C-O 3.56Å; L206-S267 WeakPolarHBondContact CA-O 3.46Å; R207-S267 PolarHBondContact N-O 3.04Å; R207-S267 PolarHBondContact O-N 3.5Å; S267-M269 PolarHBondContact O-N 2.68Å
268T95.2Very high92.1Very high59 Ų5954 Ų5436%0.36229%0.289SS..EExtended strand (participates in β ladder)trans-80.2116.2173.6-56.90000109.2Q204 L206 I270 E271Q204-T268 HydrophobicContact CB-CG2 4.42Å; L206-T268 HydrophobicContact CD2-CG2 4.35Å; T268-I270 WeakPolarHBondContact CG2-O 3.4Å; T268-E271 HydrophobicContact CG2-CG 4.07Å
269M92.3Very high91.6Very high45 Ų4557.8 Ų57.822%0.22231%0.309CS..EExtended strand (participates in β ladder)trans-83.2-44.9175.8-56.9-168.281.900111.8V205 R207 D244 S267 G567V205-M269 HydrophobicContact CB-CB 4.41Å; V205-M269 HydrophobicContact CG1-CB 4.38Å; V205-M269 HydrophobicContact CG1-SD 4.26Å; V205-M269 WeakPolarHBondContact O-CB 3.31Å; V205-M269 PolarHBondContact O-N 3.41Å; R207-M269 HydrophobicContact CB-CG 3.54Å; R207-M269 HydrophobicContact CB-SD 3.64Å; R207-M269 VanDerWaalsContact NH2-CE 3.3Å; D244-M269 HydrophobicContact CB-SD 4.19Å; D244-M269 VanDerWaalsContact CG-SD 3.51Å; D244-M269 VanDerWaalsContact OD1-SD 3.39Å; S267-M269 PolarHBondContact O-N 2.68Å; M269-G567 WeakPolarHBondContact CE-O 3.22Å
270I91.7Very high91.2Very high6 Ų658.4 Ų58.43%0.03131%0.312CS..EExtended strand (participates in β ladder)trans-129.1118.9-178.9-62.3171.7000106.8Q204 V205 W233 T268 V273 I276Q204-I270 VanDerWaalsContact CA-O 3.29Å; Q204-I270 WeakPolarHBondContact CA-O 3.46Å; V205-I270 HydrophobicContact CB-CB 3.95Å; V205-I270 HydrophobicContact CB-CD1 4.23Å; V205-I270 HydrophobicContact CB-CG1 4.27Å; V205-I270 HydrophobicContact CG2-CB 4.04Å; V205-I270 HydrophobicContact CG2-CD1 3.92Å; V205-I270 HydrophobicContact CG2-CG1 4.38Å; V205-I270 PolarHBondContact N-O 3.15Å; V205-I270 PolarHBondContact O-N 3.47Å; W233-I270 HydrophobicContact CH2-CD1 3.95Å; W233-I270 HydrophobicContact CZ3-CD1 3.77Å; T268-I270 WeakPolarHBondContact CG2-O 3.4Å; I270-V273 HydrophobicContact CG2-CG2 3.99Å; I270-I276 HydrophobicContact CB-CD1 4.45Å; I270-I276 HydrophobicContact CD1-CD1 4.03Å; I270-I276 HydrophobicContact CG1-CD1 4.05Å; I270-I276 HydrophobicContact CG2-CD1 3.62Å; I270-I276 HydrophobicContact CG2-CG1 4.43Å
271E94.3Very high90.7Very high157 Ų15756.9 Ų56.973%0.73430%0.299SS*.SBendtrans-76.7-33.3-178.2-66.7-173.7172.700113Q204 T268Q204-E271 WeakPolarHBondContact CG-O 3.07Å; Q204-E271 PolarHBondContact NE2-O 3.41Å; T268-E271 HydrophobicContact CG2-CG 4.07Å
272D91.7Very high90Very high57 Ų5757.4 Ų57.431%0.30529%0.293SS..  trans-148.2109.8176.3-172.8-4.3000109.9G202 H203 Q274 A275G202-D272 PolarHBondContact N-OD1 3.32Å; H203-D272 WeakPolarHBondContact O-CA 3.46Å; D272-Q274 VanDerWaalsContact C-N 3.28Å; D272-Q274 PolarHBondContact O-N 2.97Å; D272-Q274 WeakPolarHBondContact OD1-CB 3.31Å; D272-Q274 PolarHBondContact OD1-N 3Å; D272-A275 HydrophobicContact CB-CB 4.05Å; D272-A275 PolarHBondContact O-N 2.94Å
273V90.3Very high89.3Confident0 Ų058.4 Ų58.40%030%0.298CS..Hα-helixtrans-63-36177174.60000110.9F200 H203 V205 R246 I270 A275 I276 L277 L572F200-V273 HydrophobicContact CB-CB 4.06Å; F200-V273 HydrophobicContact CB-CG1 3.85Å; F200-V273 HydrophobicContact CG-CG1 4.18Å; H203-V273 HydrophobicContact CB-CB 4.09Å; H203-V273 HydrophobicContact CB-CG2 4.06Å; H203-V273 WeakPolarHBondContact O-CG2 3.46Å; H203-V273 PolarHBondContact O-N 3Å; V205-V273 HydrophobicContact CG2-CG2 3.84Å; R246-V273 HydrophobicContact CG-CG2 4.34Å; I270-V273 HydrophobicContact CG2-CG2 3.99Å; V273-A275 VanDerWaalsContact C-N 3.33Å; V273-A275 PolarHBondContact O-N 3.17Å; V273-I276 PolarHBondContact O-N 3.21Å; V273-L277 HydrophobicContact CG1-CD1 4.06Å; V273-L277 HydrophobicContact CG1-CG 4.34Å; V273-L277 WeakPolarHBondContact O-CG 3.24Å; V273-L277 PolarHBondContact O-N 3.38Å; V273-L277 VanDerWaalsContact O-N 3.12Å; V273-L572 HydrophobicContact CG1-CD1 4Å
274Q89.3Confident88.6Confident8 Ų853.9 Ų53.94%0.03727%0.273CS..Hα-helixtrans-64.8-37.9-179.3-170.560.353.300112F200 E201 D272 I276 L277 D278F200-Q274 HydrophobicContact CB-CB 4.49Å; E201-Q274 HydrophobicContact CG-CB 4.09Å; E201-Q274 HydrophobicContact CG-CG 3.75Å; D272-Q274 VanDerWaalsContact C-N 3.28Å; D272-Q274 PolarHBondContact O-N 2.97Å; D272-Q274 WeakPolarHBondContact OD1-CB 3.31Å; D272-Q274 PolarHBondContact OD1-N 3Å; Q274-I276 VanDerWaalsContact C-N 3.3Å; Q274-I276 PolarHBondContact O-N 2.86Å; Q274-L277 WeakPolarHBondContact O-CB 3.23Å; Q274-L277 PolarHBondContact O-N 3.5Å; Q274-L277 VanDerWaalsContact O-N 3.14Å; Q274-D278 PolarHBondContact NE2-OD1 3.15Å; Q274-D278 VanDerWaalsContact O-CG 3.26Å; Q274-D278 PolarHBondContact O-N 3.42Å
275A89Confident87.7Confident45 Ų4559.5 Ų59.537%0.37230%0.297SS..Hα-helixtrans-59.7-39.917800000112.3D272 V273 M279D272-A275 HydrophobicContact CB-CB 4.05Å; D272-A275 PolarHBondContact O-N 2.94Å; V273-A275 VanDerWaalsContact C-N 3.33Å; V273-A275 PolarHBondContact O-N 3.17Å; A275-M279 WeakPolarHBondContact O-CG 3.13Å; A275-M279 PolarHBondContact O-N 3.43Å
276I89.3Confident86.7Confident28 Ų2856.5 Ų56.514%0.14429%0.289CS..Hα-helixtrans-70.3-40.1176.4-55.4-178.1000110.9I270 V273 Q274 D278 M279 E280 L572I270-I276 HydrophobicContact CB-CD1 4.45Å; I270-I276 HydrophobicContact CD1-CD1 4.03Å; I270-I276 HydrophobicContact CG1-CD1 4.05Å; I270-I276 HydrophobicContact CG2-CD1 3.62Å; I270-I276 HydrophobicContact CG2-CG1 4.43Å; V273-I276 PolarHBondContact O-N 3.21Å; Q274-I276 VanDerWaalsContact C-N 3.3Å; Q274-I276 PolarHBondContact O-N 2.86Å; I276-D278 VanDerWaalsContact C-N 3.33Å; I276-D278 PolarHBondContact O-N 3.09Å; I276-M279 HydrophobicContact CB-CE 4.34Å; I276-M279 HydrophobicContact CG1-CE 4.15Å; I276-M279 PolarHBondContact O-N 3.49Å; I276-E280 PolarHBondContact O-N 3.43Å; I276-L572 HydrophobicContact CB-CD1 3.95Å; I276-L572 HydrophobicContact CG2-CB 3.66Å; I276-L572 HydrophobicContact CG2-CD1 3.88Å; I276-L572 HydrophobicContact CG2-CG 4.39Å
277L86.8Confident85.6Confident0 Ų054.2 Ų54.20%029%0.285CS..Hα-helixtrans-62.3-38.2175.8-70.3178.1000113.1F200 V273 Q274 E280 R281 R416 M417 L572F200-L277 HydrophobicContact CB-CD1 4.13Å; F200-L277 HydrophobicContact CD2-CD1 3.29Å; F200-L277 HydrophobicContact CE2-CD1 3.98Å; F200-L277 HydrophobicContact CG-CD1 3.99Å; V273-L277 HydrophobicContact CG1-CD1 4.06Å; V273-L277 HydrophobicContact CG1-CG 4.34Å; V273-L277 WeakPolarHBondContact O-CG 3.24Å; V273-L277 PolarHBondContact O-N 3.38Å; V273-L277 VanDerWaalsContact O-N 3.12Å; Q274-L277 WeakPolarHBondContact O-CB 3.23Å; Q274-L277 PolarHBondContact O-N 3.5Å; Q274-L277 VanDerWaalsContact O-N 3.14Å; L277-E280 PolarHBondContact O-N 3.39Å; L277-R281 WeakPolarHBondContact O-CB 3.15Å; L277-R281 VanDerWaalsContact O-CG 3.28Å; L277-R281 WeakPolarHBondContact O-CG 3.31Å; L277-R281 PolarHBondContact O-N 2.95Å; L277-R416 HydrophobicContact CD2-CB 3.98Å; L277-R416 HydrophobicContact CD2-CG 3.35Å; L277-M417 HydrophobicContact CD2-CE 4.35Å; L277-L572 HydrophobicContact CD2-CD1 4.05Å; L277-L572 HydrophobicContact CD2-CD2 3.49Å; L277-L572 VanDerWaalsContact CD2-CD2 3.49Å; L277-L572 HydrophobicContact CD2-CG 4.44Å; L277-L572 HydrophobicContact CG-CD1 4.17Å; L277-L572 HydrophobicContact CG-CD2 4.47Å
278D83.3Confident84.6Confident82 Ų8253.9 Ų53.944%0.43929%0.286SS..Hα-helixtrans-68-38.6178.1-69-19.7000111.1Q274 I276 R281 E282Q274-D278 PolarHBondContact NE2-OD1 3.15Å; Q274-D278 VanDerWaalsContact O-CG 3.26Å; Q274-D278 PolarHBondContact O-N 3.42Å; I276-D278 VanDerWaalsContact C-N 3.33Å; I276-D278 PolarHBondContact O-N 3.09Å; D278-R281 PolarHBondContact O-N 3.24Å; D278-E282 WeakPolarHBondContact O-CB 3.3Å; D278-E282 PolarHBondContact O-N 3.31Å
279M83.6Confident83.3Confident108 Ų10860.2 Ų60.253%0.53230%0.303SS..Hα-helixtrans-63-44.9171.7-70.4-172.5-7100112.3A275 I276 E282 Q283A275-M279 WeakPolarHBondContact O-CG 3.13Å; A275-M279 PolarHBondContact O-N 3.43Å; I276-M279 HydrophobicContact CB-CE 4.34Å; I276-M279 HydrophobicContact CG1-CE 4.15Å; I276-M279 PolarHBondContact O-N 3.49Å; M279-E282 PolarHBondContact O-N 2.93Å; M279-Q283 VanDerWaalsContact O-CG 3.3Å; M279-Q283 WeakPolarHBondContact O-CG 3.45Å; M279-Q283 PolarHBondContact O-N 2.92Å
280E85.7Confident82.3Confident13 Ų1363.6 Ų63.66%0.06132%0.321CS..Hα-helixtrans-58.2-49.3175.6-178.7-174.974.800110.8I276 L277 E282 Q283 M284 Y304 W365 R416I276-E280 PolarHBondContact O-N 3.43Å; L277-E280 PolarHBondContact O-N 3.39Å; E280-E282 PolarHBondContact O-N 3.01Å; E280-Q283 PolarHBondContact O-N 2.81Å; E280-M284 HydrophobicContact CG-SD 4.26Å; E280-M284 WeakPolarHBondContact O-CG 3.38Å; E280-M284 PolarHBondContact O-N 3.24Å; E280-Y304 HydrophobicContact CG-CD2 4.36Å; E280-W365 HydrophobicContact CG-CZ3 4.01Å; E280-W365 VanDerWaalsContact OE1-CZ3 3.26Å; E280-W365 WeakPolarHBondContact OE1-CZ3 3.43Å; E280-R416 IonicContact OE1-CZ 3.08Å; E280-R416 IonicContact OE1-NE 3.65Å; E280-R416 PolarHBondContact OE1-NE 3.37Å; E280-R416 IonicContact OE1-NH2 3.91Å; E280-R416 IonicContact OE2-CZ 3.98Å; E280-R416 IonicContact OE2-NE 3.95Å; E280-R416 PolarHBondContact OE2-NE 3.37Å; E280-R416 IonicContact OE2-NH2 3.74Å; E280-R416 PolarHBondContact OE2-NH2 2.84Å
281R83.8Confident81.3Confident59 Ų5969.3 Ų69.322%0.22336%0.356CS..Hα-helixtrans-64-41-179.7-75.5172.5173.5175.61.2112.6L277 D278 M284 K285L277-R281 WeakPolarHBondContact O-CB 3.15Å; L277-R281 VanDerWaalsContact O-CG 3.28Å; L277-R281 WeakPolarHBondContact O-CG 3.31Å; L277-R281 PolarHBondContact O-N 2.95Å; D278-R281 PolarHBondContact O-N 3.24Å; R281-M284 PolarHBondContact O-N 2.77Å; R281-K285 WeakPolarHBondContact O-CB 3.3Å; R281-K285 VanDerWaalsContact O-CG 3.27Å; R281-K285 WeakPolarHBondContact O-CG 3.29Å; R281-K285 PolarHBondContact O-N 3.14Å
282E79.5Confident80.4Confident93 Ų9367.3 Ų67.344%0.43535%0.347SS..Hα-helixtrans-68.5-36.8179.3-171.856.6-157.400111.8D278 M279 E280 S286D278-E282 WeakPolarHBondContact O-CB 3.3Å; D278-E282 PolarHBondContact O-N 3.31Å; M279-E282 PolarHBondContact O-N 2.93Å; E280-E282 PolarHBondContact O-N 3.01Å; E282-S286 VanDerWaalsContact O-CB 3.27Å; E282-S286 WeakPolarHBondContact O-CB 3.38Å; E282-S286 PolarHBondContact O-N 3.44Å; E282-S286 PolarHBondContact O-OG 2.84Å
283Q77.6Confident80Confident89 Ų8966.4 Ų66.442%0.41634%0.344SS..Hα-helixtrans-62.1-48.5172.2-74.1173.4700111.2M279 E280 K285 S286 A287M279-Q283 VanDerWaalsContact O-CG 3.3Å; M279-Q283 WeakPolarHBondContact O-CG 3.45Å; M279-Q283 PolarHBondContact O-N 2.92Å; E280-Q283 PolarHBondContact O-N 2.81Å; Q283-K285 PolarHBondContact O-N 2.72Å; Q283-S286 PolarHBondContact O-N 3.45Å; Q283-A287 WeakPolarHBondContact O-CB 3.32Å; Q283-A287 PolarHBondContact O-N 2.78Å
284M80.2Confident79.7Confident33 Ų3376.8 Ų76.816%0.16338%0.383CS..Hα-helixtrans-62.1-43.8177.5-71.5177.269.400112.6E280 R281 S286 A287 A288 W365 H412E280-M284 HydrophobicContact CG-SD 4.26Å; E280-M284 WeakPolarHBondContact O-CG 3.38Å; E280-M284 PolarHBondContact O-N 3.24Å; R281-M284 PolarHBondContact O-N 2.77Å; M284-S286 VanDerWaalsContact C-N 3.32Å; M284-S286 PolarHBondContact O-N 3.27Å; M284-A287 PolarHBondContact O-N 2.85Å; M284-A288 WeakPolarHBondContact O-CB 3.37Å; M284-A288 PolarHBondContact O-N 2.91Å; M284-W365 HydrophobicContact CE-CH2 4.31Å; M284-W365 HydrophobicContact CE-CZ3 4.22Å; M284-W365 HydrophobicContact SD-CH2 3.98Å; M284-W365 HydrophobicContact SD-CZ3 3.51Å; M284-W365 VanDerWaalsContact SD-CZ3 3.51Å; M284-H412 VanDerWaalsContact CE-CE1 3.46Å; M284-H412 WeakPolarHBondContact CE-CE1 3.27Å
285K75.1Confident79.8Confident120 Ų12079.3 Ų79.352%0.52240%0.397SS..Hα-helixtrans-61.8-41.5175.9-76.4175.3-177178.60111.7R281 Q283 A288 R289R281-K285 WeakPolarHBondContact O-CB 3.3Å; R281-K285 VanDerWaalsContact O-CG 3.27Å; R281-K285 WeakPolarHBondContact O-CG 3.29Å; R281-K285 PolarHBondContact O-N 3.14Å; Q283-K285 PolarHBondContact O-N 2.72Å; K285-A288 PolarHBondContact O-N 2.7Å; K285-R289 WeakPolarHBondContact O-CG 3.39Å; K285-R289 PolarHBondContact O-N 2.71Å
286S71.9Confident79.9Confident52 Ų5277.1 Ų77.136%0.36438%0.379SS..Hα-helixtrans-64.1-42.8177.3-64.50000111.4E282 Q283 M284 R289E282-S286 VanDerWaalsContact O-CB 3.27Å; E282-S286 WeakPolarHBondContact O-CB 3.38Å; E282-S286 PolarHBondContact O-N 3.44Å; E282-S286 PolarHBondContact O-OG 2.84Å; Q283-S286 PolarHBondContact O-N 3.45Å; M284-S286 VanDerWaalsContact C-N 3.32Å; M284-S286 PolarHBondContact O-N 3.27Å; S286-R289 PolarHBondContact O-N 2.93Å
287A72.3Confident80Confident23 Ų2381.7 Ų81.719%0.1940%0.404CS..Hα-helixtrans-64.9-41.7175.100000112Q283 M284 R289 L290 N303Q283-A287 WeakPolarHBondContact O-CB 3.32Å; Q283-A287 PolarHBondContact O-N 2.78Å; M284-A287 PolarHBondContact O-N 2.85Å; A287-R289 PolarHBondContact O-N 3.33Å; A287-L290 VanDerWaalsContact O-CB 3.22Å; A287-L290 WeakPolarHBondContact O-CB 3.28Å; A287-L290 WeakPolarHBondContact O-CG 3.26Å; A287-L290 PolarHBondContact O-N 3.1Å; A287-N303 HydrophobicContact CB-CB 4.36Å
288A72.9Confident80.1Confident55 Ų5584.7 Ų84.746%0.45543%0.425SS..Hα-helixtrans-66.2-21.2178.900000114M284 K285 L290M284-A288 WeakPolarHBondContact O-CB 3.37Å; M284-A288 PolarHBondContact O-N 2.91Å; K285-A288 PolarHBondContact O-N 2.7Å; A288-L290 VanDerWaalsContact C-N 3.25Å
289R68.8Low80.4Confident192 Ų19281.4 Ų81.473%0.72541%0.407SS*.THydrogen-bonded Turntrans-74.9-14.1172.4-72.7172.1-179164.12.9113K285 S286 A287K285-R289 WeakPolarHBondContact O-CG 3.39Å; K285-R289 PolarHBondContact O-N 2.71Å; S286-R289 PolarHBondContact O-N 2.93Å; A287-R289 PolarHBondContact O-N 3.33Å
290L71.1Confident80.7Confident116 Ų11678.8 Ų78.861%0.60740%0.395SS*.SBendtrans-72161.6174.5-59.3174000110.5A287 A288 Q292A287-L290 VanDerWaalsContact O-CB 3.22Å; A287-L290 WeakPolarHBondContact O-CB 3.28Å; A287-L290 WeakPolarHBondContact O-CG 3.26Å; A287-L290 PolarHBondContact O-N 3.1Å; A288-L290 VanDerWaalsContact C-N 3.25Å; L290-Q292 PolarHBondContact O-N 3.21Å
291V70.2Confident81Confident126 Ų12679.6 Ų79.676%0.76440%0.398SS*.PPolyproline II helixtrans-60.2126.5179.1179.40000109
292Q76.7Confident81.3Confident115 Ų11578.4 Ų78.454%0.53740%0.4SS..PPolyproline II helixtrans-49.5134.6176-73.9-68.9-32.500110.8L290 R294L290-Q292 PolarHBondContact O-N 3.21Å; Q292-R294 PolarHBondContact O-N 3.01Å
293P82.8Confident81.9Confident38 Ų3875.4 Ų75.425%0.24739%0.387CS..PPolyproline II helixtrans-61.3134.5-175.925.5-33.5000109.9F299 M316P293-F299 HydrophobicContact CB-CB 4.3Å; P293-F299 HydrophobicContact CB-CD2 4.2Å; P293-F299 HydrophobicContact CG-CD2 3.78Å; P293-F299 HydrophobicContact CG-CE2 4.4Å; P293-M316 HydrophobicContact CB-CE 4.42Å; P293-M316 HydrophobicContact CG-CE 4.17Å
294R84.4Confident82.6Confident218 Ų21871.6 Ų71.682%0.82337%0.369SS*.SBendtrans-88.7-22.6179.1-66.3-177.2-179172.20.7112.6Q292 S298Q292-R294 PolarHBondContact O-N 3.01Å; R294-S298 PolarHBondContact N-OG 3.29Å
295N90.3Very high83.2Confident60 Ų6070.9 Ų70.932%0.32137%0.365SS..SBendtrans-158.5171.3-176.259.936.4000108.8D297 S298 F299 E320N295-D297 VanDerWaalsContact C-N 3.27Å; N295-D297 PolarHBondContact O-N 3.25Å; N295-D297 PolarHBondContact OD1-N 3.48Å; N295-S298 PolarHBondContact N-OG 3.42Å; N295-S298 PolarHBondContact O-N 2.91Å; N295-S298 PolarHBondContact O-OG 3.42Å; N295-S298 PolarHBondContact OD1-N 3.34Å; N295-S298 PolarHBondContact OD1-OG 3.12Å; N295-S298 VanDerWaalsContact OD1-OG 3.1Å; N295-F299 PolarHBondContact O-N 3.45Å; N295-E320 WeakPolarHBondContact CA-OE1 3.39Å; N295-E320 WeakPolarHBondContact CB-OE1 3.16Å
296T92.5Very high84Confident0 Ų067.2 Ų67.20%035%0.353CS..G310 helixtrans-68.3-21.6-178.468.90000113.9S298 F299 Y301 F313 M316 L317 E320 K376T296-S298 VanDerWaalsContact C-N 3.33Å; T296-F299 WeakPolarHBondContact O-CB 3.24Å; T296-F299 PolarHBondContact O-N 2.91Å; T296-Y301 WeakPolarHBondContact O-CE2 3.4Å; T296-Y301 PolarHBondContact O-OH 3.14Å; T296-F313 HydrophobicContact CG2-CD2 3.9Å; T296-F313 HydrophobicContact CG2-CE2 3.59Å; T296-M316 HydrophobicContact CG2-CB 3.85Å; T296-L317 HydrophobicContact CG2-CB 3.99Å; T296-L317 HydrophobicContact CG2-CD1 3.97Å; T296-E320 WeakPolarHBondContact CB-OE2 3.26Å; T296-E320 WeakPolarHBondContact CG2-OE2 3.43Å; T296-E320 PolarHBondContact N-OE1 3.03Å; T296-E320 PolarHBondContact OG1-OE2 3.09Å; T296-K376 PolarHBondContact OG1-NZ 3.16Å
297D89.6Confident85.1Confident123 Ų12365.2 Ų65.266%0.65834%0.338SS*.G310 helixtrans-71.5-29.2175-66.5-28.4000112.6N295 K376N295-D297 VanDerWaalsContact C-N 3.27Å; N295-D297 PolarHBondContact O-N 3.25Å; N295-D297 PolarHBondContact OD1-N 3.48Å; D297-K376 VanDerWaalsContact OD1-CE 3.3Å; D297-K376 WeakPolarHBondContact OD1-CE 3.34Å; D297-K376 IonicContact OD1-NZ 3.73Å; D297-K376 PolarHBondContact OD1-NZ 3.1Å
298S89Confident86Confident64 Ų6467.9 Ų67.945%0.44836%0.356SS..G310 helixtrans-91.40.617664.10000113.9R294 N295 T296R294-S298 PolarHBondContact N-OG 3.29Å; N295-S298 PolarHBondContact N-OG 3.42Å; N295-S298 PolarHBondContact O-N 2.91Å; N295-S298 PolarHBondContact O-OG 3.42Å; N295-S298 PolarHBondContact OD1-N 3.34Å; N295-S298 PolarHBondContact OD1-OG 3.12Å; N295-S298 VanDerWaalsContact OD1-OG 3.1Å; T296-S298 VanDerWaalsContact C-N 3.33Å
299F90.6Very high86.9Confident13 Ų1367.2 Ų67.26%0.05734%0.343CS..SBendtrans-74.8140.1178.3-168.8-86.5000110.7P293 N295 T296 Y301 H305 F313 M316 L372P293-F299 HydrophobicContact CB-CB 4.3Å; P293-F299 HydrophobicContact CB-CD2 4.2Å; P293-F299 HydrophobicContact CG-CD2 3.78Å; P293-F299 HydrophobicContact CG-CE2 4.4Å; N295-F299 PolarHBondContact O-N 3.45Å; T296-F299 WeakPolarHBondContact O-CB 3.24Å; T296-F299 PolarHBondContact O-N 2.91Å; F299-Y301 HydrophobicContact CB-CE2 4.07Å; F299-Y301 AromaticContact CD1-CD1 3.99Å; F299-Y301 HydrophobicContact CD1-CD1 3.99Å; F299-Y301 HydrophobicContact CD1-CD2 4.43Å; F299-Y301 AromaticContact CD1-CE1 3.79Å; F299-Y301 HydrophobicContact CD1-CE1 3.79Å; F299-Y301 HydrophobicContact CD1-CE2 4.26Å; F299-Y301 HydrophobicContact CD1-CG 4.3Å; F299-Y301 AromaticContact CD1-CZ 3.93Å; F299-Y301 HydrophobicContact CE1-CD1 4.44Å; F299-Y301 HydrophobicContact CE1-CE1 4.42Å; F299-Y301 VanDerWaalsContact O-CD2 3.26Å; F299-Y301 WeakPolarHBondContact O-CD2 3.37Å; F299-Y301 WeakPolarHBondContact O-CE2 3.37Å; F299-Y301 PolarHBondContact O-N 2.77Å; F299-H305 AromaticContact CE1-CD2 3.48Å; F299-H305 VanDerWaalsContact CE1-CD2 3.48Å; F299-H305 WeakPolarHBondContact CE1-CD2 3.4Å; F299-H305 AromaticContact CE1-CE1 3.9Å; F299-H305 AromaticContact CE1-NE2 3.23Å; F299-H305 WeakPolarHBondContact CE1-NE2 3.46Å; F299-H305 AromaticContact CZ-CD2 3.44Å; F299-H305 VanDerWaalsContact CZ-CD2 3.44Å; F299-H305 WeakPolarHBondContact CZ-CD2 3.33Å; F299-H305 AromaticContact CZ-CE1 3.71Å; F299-H305 AromaticContact CZ-CG 3.71Å; F299-H305 AromaticContact CZ-ND1 3.88Å; F299-H305 AromaticContact CZ-NE2 3.42Å; F299-H305 WeakPolarHBondContact CZ-NE2 3.42Å; F299-F313 HydrophobicContact CD1-CD2 4.27Å; F299-F313 HydrophobicContact CD2-CB 4.16Å; F299-F313 HydrophobicContact CD2-CD2 4.07Å; F299-F313 HydrophobicContact CE2-CB 3.77Å; F299-F313 HydrophobicContact CE2-CD2 4.38Å; F299-F313 HydrophobicContact CE2-CG 4.39Å; F299-F313 HydrophobicContact CG-CD2 4.02Å; F299-F313 HydrophobicContact CZ-CB 4.12Å; F299-F313 HydrophobicContact CZ-CG 4.5Å; F299-M316 HydrophobicContact CD2-CE 4.07Å; F299-L372 HydrophobicContact CE1-CD1 3.95Å; F299-L372 HydrophobicContact CZ-CD1 4.11Å
300D90.6Very high88.3Confident52 Ų5258.1 Ų58.128%0.27831%0.309SS..  trans-90.787-173.9-175.41.5000112.7A302 N303 H305D300-A302 PolarHBondContact O-N 3.12Å; D300-A302 VanDerWaalsContact O-N 3.07Å; D300-A302 WeakPolarHBondContact OD1-CB 3.39Å; D300-A302 PolarHBondContact OD1-N 2.84Å; D300-N303 PolarHBondContact O-N 3Å; D300-N303 PolarHBondContact OD2-ND2 2.77Å; D300-H305 PolarHBondContact O-NE2 2.99Å
301Y91.2Very high89.6Confident31 Ų3154.2 Ų54.212%0.12229%0.286CS..THydrogen-bonded Turntrans-70.1-1.2178.5-58.1-82.3000115.1T296 F299 F313 L372 W373 K376 I578T296-Y301 WeakPolarHBondContact O-CE2 3.4Å; T296-Y301 PolarHBondContact O-OH 3.14Å; F299-Y301 HydrophobicContact CB-CE2 4.07Å; F299-Y301 AromaticContact CD1-CD1 3.99Å; F299-Y301 HydrophobicContact CD1-CD1 3.99Å; F299-Y301 HydrophobicContact CD1-CD2 4.43Å; F299-Y301 AromaticContact CD1-CE1 3.79Å; F299-Y301 HydrophobicContact CD1-CE1 3.79Å; F299-Y301 HydrophobicContact CD1-CE2 4.26Å; F299-Y301 HydrophobicContact CD1-CG 4.3Å; F299-Y301 AromaticContact CD1-CZ 3.93Å; F299-Y301 HydrophobicContact CE1-CD1 4.44Å; F299-Y301 HydrophobicContact CE1-CE1 4.42Å; F299-Y301 VanDerWaalsContact O-CD2 3.26Å; F299-Y301 WeakPolarHBondContact O-CD2 3.37Å; F299-Y301 WeakPolarHBondContact O-CE2 3.37Å; F299-Y301 PolarHBondContact O-N 2.77Å; Y301-F313 AromaticContact CE1-CE2 3.97Å; Y301-F313 HydrophobicContact CE1-CE2 3.97Å; Y301-F313 HydrophobicContact CE1-CZ 4.19Å; Y301-F313 AromaticContact CZ-CE2 3.95Å; Y301-F313 WeakPolarHBondContact OH-CE2 3.32Å; Y301-L372 HydrophobicContact CD1-CB 4.33Å; Y301-L372 HydrophobicContact CE1-CB 4.39Å; Y301-W373 HydrophobicContact CD1-CB 4.31Å; Y301-K376 HydrophobicContact CE1-CB 3.82Å; Y301-K376 HydrophobicContact CE1-CG 4.36Å; Y301-K376 HydrophobicContact CE2-CB 4.44Å; Y301-K376 HydrophobicContact CE2-CG 4.08Å; Y301-K376 WeakPolarHBondContact OH-CB 3.47Å; Y301-K376 VanDerWaalsContact OH-CG 3.29Å; Y301-K376 WeakPolarHBondContact OH-CG 3Å; Y301-I578 VanDerWaalsContact O-CG2 3.32Å; Y301-I578 WeakPolarHBondContact O-CG2 3.37Å
302A90.1Very high90.8Very high34 Ų3451.3 Ų51.328%0.28127%0.272SS..THydrogen-bonded Turntrans-96.45.9-179.700000113.1D300 A575 I579D300-A302 PolarHBondContact O-N 3.12Å; D300-A302 VanDerWaalsContact O-N 3.07Å; D300-A302 WeakPolarHBondContact OD1-CB 3.39Å; D300-A302 PolarHBondContact OD1-N 2.84Å; A302-A575 CarbonylContact O-C 3.57Å; A302-A575 WeakPolarHBondContact O-CB 3.43Å; A302-I579 HydrophobicContact CB-CD1 3.78Å; A302-I579 HydrophobicContact CB-CG1 4.45Å
303N91.7Very high91.7Very high29 Ų2945.9 Ų45.916%0.15525%0.246CC..SBendtrans-131.3164-178.4-82.6-63.5000113.2A287 D300 H305A287-N303 HydrophobicContact CB-CB 4.36Å; D300-N303 PolarHBondContact O-N 3Å; D300-N303 PolarHBondContact OD2-ND2 2.77Å; N303-H305 PolarHBondContact O-CD2 2.9Å; N303-H305 PolarHBondContact O-NE2 2.9Å
304Y93.1Very high92.5Very high10 Ų1044 Ų444%0.03923%0.234CC..  trans-83144171.7-67.1-57.7000110.9E280 W365 A369 L573 I578E280-Y304 HydrophobicContact CG-CD2 4.36Å; Y304-W365 HydrophobicContact CD1-CB 3.74Å; Y304-W365 HydrophobicContact CD1-CE3 4.15Å; Y304-W365 AromaticContact CD2-CE3 3.79Å; Y304-W365 HydrophobicContact CD2-CE3 3.79Å; Y304-W365 HydrophobicContact CD2-CZ3 4.37Å; Y304-W365 VanDerWaalsContact CE1-C 3.5Å; Y304-W365 HydrophobicContact CE1-CB 3.56Å; Y304-W365 WeakPolarHBondContact CE1-O 3.42Å; Y304-W365 HydrophobicContact CE2-CE3 4.38Å; Y304-W365 HydrophobicContact CG-CB 4.41Å; Y304-W365 AromaticContact CG-CE3 3.66Å; Y304-W365 HydrophobicContact CG-CE3 3.66Å; Y304-W365 HydrophobicContact CG-CZ3 4.35Å; Y304-A369 HydrophobicContact CD1-CB 3.99Å; Y304-A369 HydrophobicContact CE1-CB 4Å; Y304-L573 WeakPolarHBondContact CE2-O 3.47Å; Y304-L573 PolarHBondContact OH-O 3.12Å; Y304-I578 HydrophobicContact CD1-CD1 3.77Å; Y304-I578 HydrophobicContact CD2-CD1 4.36Å; Y304-I578 HydrophobicContact CE1-CD1 3.63Å; Y304-I578 HydrophobicContact CE1-CG1 3.9Å; Y304-I578 HydrophobicContact CE2-CD1 4.26Å; Y304-I578 HydrophobicContact CG-CD1 4.13Å
305H91.6Very high93.1Very high17 Ų1737.7 Ų37.78%0.07922%0.217CC..  trans-126.1146.3-173.2-67.9-66.6000112.2F299 D300 N303 E309 I310 L372 Y408 H412F299-H305 AromaticContact CE1-CD2 3.48Å; F299-H305 VanDerWaalsContact CE1-CD2 3.48Å; F299-H305 WeakPolarHBondContact CE1-CD2 3.4Å; F299-H305 AromaticContact CE1-CE1 3.9Å; F299-H305 AromaticContact CE1-NE2 3.23Å; F299-H305 WeakPolarHBondContact CE1-NE2 3.46Å; F299-H305 AromaticContact CZ-CD2 3.44Å; F299-H305 VanDerWaalsContact CZ-CD2 3.44Å; F299-H305 WeakPolarHBondContact CZ-CD2 3.33Å; F299-H305 AromaticContact CZ-CE1 3.71Å; F299-H305 AromaticContact CZ-CG 3.71Å; F299-H305 AromaticContact CZ-ND1 3.88Å; F299-H305 AromaticContact CZ-NE2 3.42Å; F299-H305 WeakPolarHBondContact CZ-NE2 3.42Å; D300-H305 PolarHBondContact O-NE2 2.99Å; N303-H305 PolarHBondContact O-CD2 2.9Å; N303-H305 PolarHBondContact O-NE2 2.9Å; H305-E309 WeakPolarHBondContact CA-OE2 3.31Å; H305-E309 HydrophobicContact CB-CB 3.96Å; H305-E309 IonicContact ND1-OE2 3.7Å; H305-I310 HydrophobicContact CB-CG1 4.27Å; H305-L372 HydrophobicContact CB-CD1 4.47Å; H305-Y408 WeakPolarHBondContact O-CE1 3.46Å; H305-Y408 PolarHBondContact O-OH 3.48Å; H305-H412 PolarHBondContact O-CE1 2.66Å; H305-H412 VanDerWaalsContact O-CE1 3.29Å; H305-H412 PolarHBondContact O-NE2 2.79Å
306T93.2Very high93.4Very high44 Ų4436.5 Ų36.527%0.2721%0.209SC..  trans-64.2160.1170.563.30000111.1S308 E309 I310T306-S308 PolarHBondContact O-N 3.13Å; T306-S308 PolarHBondContact OG1-OG 3.1Å; T306-E309 WeakPolarHBondContact CB-OE2 3.47Å; T306-E309 PolarHBondContact N-OE2 3.25Å; T306-E309 PolarHBondContact O-N 3.18Å; T306-E309 VanDerWaalsContact O-N 3.12Å; T306-E309 VanDerWaalsContact OG1-CD 3.27Å; T306-E309 VanDerWaalsContact OG1-CG 3.3Å; T306-E309 WeakPolarHBondContact OG1-CG 3.4Å; T306-E309 PolarHBondContact OG1-N 2.89Å; T306-E309 PolarHBondContact OG1-OE2 2.86Å; T306-I310 PolarHBondContact O-N 3.32Å
307L93.6Very high93.7Very high10 Ų1036.5 Ų36.55%0.05221%0.209CC..Hα-helixtrans-57.3-37.2176.8-174.164.7000112.7I310 Y311 R337 A402 P405 Y408L307-I310 PolarHBondContact O-N 3.22Å; L307-Y311 HydrophobicContact CD1-CD1 4.2Å; L307-Y311 HydrophobicContact CD1-CE1 3.62Å; L307-Y311 HydrophobicContact CD2-CE2 4.43Å; L307-Y311 HydrophobicContact CG-CE1 4.16Å; L307-Y311 HydrophobicContact CG-CE2 4.27Å; L307-Y311 PolarHBondContact O-N 3.14Å; L307-R337 VanDerWaalsContact CD2-CD 3.46Å; L307-A402 HydrophobicContact CD1-CB 3.84Å; L307-P405 HydrophobicContact CD1-CB 4.03Å; L307-P405 HydrophobicContact CD2-CB 3.81Å; L307-Y408 HydrophobicContact CB-CD1 4.11Å; L307-Y408 HydrophobicContact CD1-CD1 4.17Å
308S92.2Very high94.1Very high79 Ų7932.3 Ų32.355%0.55219%0.188SC*.Hα-helixtrans-64.8-37.8177.638.60000112.9T306 Y311 S312T306-S308 PolarHBondContact O-N 3.13Å; T306-S308 PolarHBondContact OG1-OG 3.1Å; S308-Y311 PolarHBondContact O-N 3.47Å; S308-S312 WeakPolarHBondContact O-CB 3.46Å; S308-S312 PolarHBondContact O-N 3.03Å; S308-S312 PolarHBondContact O-OG 2.94Å
309E92.7Very high94.5Very high41 Ų4133 Ų3319%0.19220%0.198CC..Hα-helixtrans-70.3-38.6176.6-72.2164.1141.800110.9H305 T306 S312 F313H305-E309 WeakPolarHBondContact CA-OE2 3.31Å; H305-E309 HydrophobicContact CB-CB 3.96Å; H305-E309 IonicContact ND1-OE2 3.7Å; T306-E309 WeakPolarHBondContact CB-OE2 3.47Å; T306-E309 PolarHBondContact N-OE2 3.25Å; T306-E309 PolarHBondContact O-N 3.18Å; T306-E309 VanDerWaalsContact O-N 3.12Å; T306-E309 VanDerWaalsContact OG1-CD 3.27Å; T306-E309 VanDerWaalsContact OG1-CG 3.3Å; T306-E309 WeakPolarHBondContact OG1-CG 3.4Å; T306-E309 PolarHBondContact OG1-N 2.89Å; T306-E309 PolarHBondContact OG1-OE2 2.86Å; E309-S312 PolarHBondContact O-N 3.26Å; E309-F313 WeakPolarHBondContact O-CB 3.38Å; E309-F313 PolarHBondContact O-N 3.14Å
310I97.4Very high94.8Very high0 Ų035.7 Ų35.70%021%0.211CC..Hα-helixtrans-59-48.6172.2-66.5173.5000110.8H305 T306 L307 S312 F313 Q314 Q368 L372 I401 Y408H305-I310 HydrophobicContact CB-CG1 4.27Å; T306-I310 PolarHBondContact O-N 3.32Å; L307-I310 PolarHBondContact O-N 3.22Å; I310-S312 VanDerWaalsContact C-N 3.34Å; I310-S312 PolarHBondContact O-N 3.49Å; I310-F313 WeakPolarHBondContact O-CB 3.39Å; I310-F313 PolarHBondContact O-N 3.16Å; I310-Q314 WeakPolarHBondContact O-CG 3.25Å; I310-Q314 PolarHBondContact O-N 3.27Å; I310-Q368 HydrophobicContact CD1-CB 4.24Å; I310-L372 HydrophobicContact CB-CD2 4.4Å; I310-L372 HydrophobicContact CG1-CD1 4.11Å; I310-L372 HydrophobicContact CG1-CD2 4.2Å; I310-L372 HydrophobicContact CG1-CG 4.48Å; I310-L372 HydrophobicContact CG2-CD2 4.13Å; I310-I401 HydrophobicContact CG2-CB 4.3Å; I310-I401 HydrophobicContact CG2-CG2 3.82Å; I310-Y408 HydrophobicContact CD1-CD1 4.32Å; I310-Y408 HydrophobicContact CD1-CE1 3.53Å
311Y97.4Very high95.2Very high35 Ų3535.1 Ų35.114%0.13721%0.208CC..Hα-helixtrans-64.9-39.2179.2-74.13.1000112.2L307 S308 F313 Q314 D315 P338 N340L307-Y311 HydrophobicContact CD1-CD1 4.2Å; L307-Y311 HydrophobicContact CD1-CE1 3.62Å; L307-Y311 HydrophobicContact CD2-CE2 4.43Å; L307-Y311 HydrophobicContact CG-CE1 4.16Å; L307-Y311 HydrophobicContact CG-CE2 4.27Å; L307-Y311 PolarHBondContact O-N 3.14Å; S308-Y311 PolarHBondContact O-N 3.47Å; Y311-F313 VanDerWaalsContact C-N 3.34Å; Y311-Q314 WeakPolarHBondContact O-CB 3.36Å; Y311-Q314 PolarHBondContact O-N 2.98Å; Y311-D315 PolarHBondContact O-N 3.48Å; Y311-D315 VanDerWaalsContact O-N 3.09Å; Y311-P338 HydrophobicContact CE2-CG 3.82Å; Y311-P338 PolarHBondContact OH-O 2.96Å; Y311-N340 WeakPolarHBondContact CD1-ND2 3.42Å; Y311-N340 WeakPolarHBondContact CE1-ND2 3.44Å
312S95.6Very high95.5Very high65 Ų6538 Ų3846%0.45523%0.23SC..Hα-helixtrans-64.3-39.7175.4-580000111.6S308 E309 I310 D315 M316S308-S312 WeakPolarHBondContact O-CB 3.46Å; S308-S312 PolarHBondContact O-N 3.03Å; S308-S312 PolarHBondContact O-OG 2.94Å; E309-S312 PolarHBondContact O-N 3.26Å; I310-S312 VanDerWaalsContact C-N 3.34Å; I310-S312 PolarHBondContact O-N 3.49Å; S312-D315 PolarHBondContact O-N 3.16Å; S312-M316 WeakPolarHBondContact O-CG 3.38Å; S312-M316 PolarHBondContact O-N 3.38Å
313F97.2Very high95.8Very high0 Ų044 Ų440%026%0.257CS..Hα-helixtrans-59.7-45.2172.4166.6-97.2000112.2T296 F299 Y301 E309 I310 Y311 D315 M316 L317 L372 A375 K376 I401T296-F313 HydrophobicContact CG2-CD2 3.9Å; T296-F313 HydrophobicContact CG2-CE2 3.59Å; F299-F313 HydrophobicContact CD1-CD2 4.27Å; F299-F313 HydrophobicContact CD2-CB 4.16Å; F299-F313 HydrophobicContact CD2-CD2 4.07Å; F299-F313 HydrophobicContact CE2-CB 3.77Å; F299-F313 HydrophobicContact CE2-CD2 4.38Å; F299-F313 HydrophobicContact CE2-CG 4.39Å; F299-F313 HydrophobicContact CG-CD2 4.02Å; F299-F313 HydrophobicContact CZ-CB 4.12Å; F299-F313 HydrophobicContact CZ-CG 4.5Å; Y301-F313 AromaticContact CE1-CE2 3.97Å; Y301-F313 HydrophobicContact CE1-CE2 3.97Å; Y301-F313 HydrophobicContact CE1-CZ 4.19Å; Y301-F313 AromaticContact CZ-CE2 3.95Å; Y301-F313 WeakPolarHBondContact OH-CE2 3.32Å; E309-F313 WeakPolarHBondContact O-CB 3.38Å; E309-F313 PolarHBondContact O-N 3.14Å; I310-F313 WeakPolarHBondContact O-CB 3.39Å; I310-F313 PolarHBondContact O-N 3.16Å; Y311-F313 VanDerWaalsContact C-N 3.34Å; F313-D315 VanDerWaalsContact C-N 3.28Å; F313-D315 PolarHBondContact O-N 3.35Å; F313-M316 HydrophobicContact CB-CE 4.47Å; F313-M316 PolarHBondContact O-N 3.47Å; F313-L317 HydrophobicContact CE1-CD2 4.19Å; F313-L317 HydrophobicContact CE2-CD1 4.49Å; F313-L317 HydrophobicContact CZ-CB 4.34Å; F313-L317 HydrophobicContact CZ-CD1 4.22Å; F313-L317 HydrophobicContact CZ-CD2 4.03Å; F313-L317 HydrophobicContact CZ-CG 4.44Å; F313-L317 WeakPolarHBondContact O-CB 3.36Å; F313-L317 PolarHBondContact O-N 2.87Å; F313-L372 HydrophobicContact CB-CD2 4.1Å; F313-L372 HydrophobicContact CD1-CD2 3.16Å; F313-L372 HydrophobicContact CD1-CG 4.47Å; F313-L372 HydrophobicContact CE1-CB 4.43Å; F313-L372 HydrophobicContact CE1-CD2 3.71Å; F313-L372 HydrophobicContact CG-CD2 3.72Å; F313-A375 HydrophobicContact CE1-CB 3.87Å; F313-A375 HydrophobicContact CZ-CB 4.09Å; F313-K376 HydrophobicContact CZ-CB 4.49Å; F313-I401 HydrophobicContact CE1-CD1 4.35Å
314Q98.3Very high96.1Very high0 Ų043.5 Ų43.50%025%0.254CS..Hα-helixtrans-58.8-41.3177-68.7175.6-33.600111.4I310 Y311 V318 K327 N340 L342 I401I310-Q314 WeakPolarHBondContact O-CG 3.25Å; I310-Q314 PolarHBondContact O-N 3.27Å; Y311-Q314 WeakPolarHBondContact O-CB 3.36Å; Y311-Q314 PolarHBondContact O-N 2.98Å; Q314-V318 WeakPolarHBondContact O-CG2 3.49Å; Q314-V318 PolarHBondContact O-N 3.19Å; Q314-V318 VanDerWaalsContact O-N 3.15Å; Q314-K327 HydrophobicContact CB-CD 4.11Å; Q314-N340 VanDerWaalsContact OE1-CB 3.27Å; Q314-N340 PolarHBondContact OE1-ND2 3.15Å; Q314-L342 HydrophobicContact CB-CD2 4.08Å; Q314-L342 HydrophobicContact CG-CD1 4.16Å; Q314-L342 HydrophobicContact CG-CD2 4.23Å; Q314-L342 HydrophobicContact CG-CG 4.21Å; Q314-I401 HydrophobicContact CG-CD1 4.38Å
315D97.3Very high96.4Very high85 Ų8543.2 Ų43.246%0.45525%0.254SS..Hα-helixtrans-65.6-44.1176.4-75.7-43.2000112.6Y311 S312 F313 V318 A319 K327Y311-D315 PolarHBondContact O-N 3.48Å; Y311-D315 VanDerWaalsContact O-N 3.09Å; S312-D315 PolarHBondContact O-N 3.16Å; F313-D315 VanDerWaalsContact C-N 3.28Å; F313-D315 PolarHBondContact O-N 3.35Å; D315-V318 PolarHBondContact O-N 3.44Å; D315-A319 WeakPolarHBondContact O-CB 3.45Å; D315-A319 PolarHBondContact O-N 3.01Å; D315-K327 WeakPolarHBondContact OD1-CE 3.46Å; D315-K327 IonicContact OD1-NZ 2.87Å; D315-K327 PolarHBondContact OD1-NZ 3.47Å; D315-K327 IonicContact OD2-NZ 2.75Å; D315-K327 PolarHBondContact OD2-NZ 2.9Å; D315-K327 VanDerWaalsContact OD2-NZ 3.08Å
316M97.3Very high96.7Very high34 Ų3444.8 Ų44.817%0.16727%0.267CS..Hα-helixtrans-60.7-45.8174.9-70.9-172.3-68.600111.7P293 T296 F299 S312 F313 V318 A319 E320P293-M316 HydrophobicContact CB-CE 4.42Å; P293-M316 HydrophobicContact CG-CE 4.17Å; T296-M316 HydrophobicContact CG2-CB 3.85Å; F299-M316 HydrophobicContact CD2-CE 4.07Å; S312-M316 WeakPolarHBondContact O-CG 3.38Å; S312-M316 PolarHBondContact O-N 3.38Å; F313-M316 HydrophobicContact CB-CE 4.47Å; F313-M316 PolarHBondContact O-N 3.47Å; M316-V318 VanDerWaalsContact C-N 3.34Å; M316-V318 PolarHBondContact O-N 3.06Å; M316-A319 PolarHBondContact O-N 2.93Å; M316-E320 WeakPolarHBondContact O-CB 3.44Å; M316-E320 VanDerWaalsContact O-CG 3.3Å; M316-E320 WeakPolarHBondContact O-CG 3.27Å; M316-E320 PolarHBondContact O-N 2.89Å
317L97.6Very high97Very high0 Ų045.9 Ų45.90%027%0.268CS..Hα-helixtrans-62-41.1-178.3-169.872.6000112.1T296 F313 N321 V325 L342 F344 A375 V379T296-L317 HydrophobicContact CG2-CB 3.99Å; T296-L317 HydrophobicContact CG2-CD1 3.97Å; F313-L317 HydrophobicContact CE1-CD2 4.19Å; F313-L317 HydrophobicContact CE2-CD1 4.49Å; F313-L317 HydrophobicContact CZ-CB 4.34Å; F313-L317 HydrophobicContact CZ-CD1 4.22Å; F313-L317 HydrophobicContact CZ-CD2 4.03Å; F313-L317 HydrophobicContact CZ-CG 4.44Å; F313-L317 WeakPolarHBondContact O-CB 3.36Å; F313-L317 PolarHBondContact O-N 2.87Å; L317-N321 WeakPolarHBondContact O-CB 3.46Å; L317-N321 PolarHBondContact O-N 3.39Å; L317-N321 VanDerWaalsContact O-N 3.11Å; L317-N321 PolarHBondContact O-ND2 2.93Å; L317-V325 HydrophobicContact CD2-CG1 4.38Å; L317-L342 HydrophobicContact CD2-CD1 3.82Å; L317-F344 HydrophobicContact CD2-CE1 4.28Å; L317-F344 HydrophobicContact CD2-CZ 4.28Å; L317-A375 HydrophobicContact CD2-CB 3.74Å; L317-V379 HydrophobicContact CD1-CG1 4.07Å; L317-V379 HydrophobicContact CD1-CG2 3.75Å; L317-V379 HydrophobicContact CG-CG1 4.41Å
318V98.5Very high97.2Very high35 Ų3547.8 Ų47.821%0.21228%0.278CS..Hα-helixtrans-65.8-45.7175.1170.70000111.1Q314 D315 M316 E320 N321 P322 V325 K327 L342Q314-V318 WeakPolarHBondContact O-CG2 3.49Å; Q314-V318 PolarHBondContact O-N 3.19Å; Q314-V318 VanDerWaalsContact O-N 3.15Å; D315-V318 PolarHBondContact O-N 3.44Å; M316-V318 VanDerWaalsContact C-N 3.34Å; M316-V318 PolarHBondContact O-N 3.06Å; V318-E320 VanDerWaalsContact C-N 3.27Å; V318-E320 PolarHBondContact O-N 3.11Å; V318-N321 CarbonylContact O-C 3.59Å; V318-N321 PolarHBondContact O-N 3.31Å; V318-P322 WeakPolarHBondContact O-CA 3.38Å; V318-V325 HydrophobicContact CG2-CG1 3.93Å; V318-K327 HydrophobicContact CG2-CB 3.97Å; V318-L342 HydrophobicContact CG2-CD2 4.02Å
319A97.9Very high97.5Very high78 Ų7848.1 Ų48.165%0.64528%0.276SS*.Hα-helixtrans-62.1-36-179.900000112.5D315 M316D315-A319 WeakPolarHBondContact O-CB 3.45Å; D315-A319 PolarHBondContact O-N 3.01Å; M316-A319 PolarHBondContact O-N 2.93Å
320E97.5Very high97.8Very high71 Ų7147.5 Ų47.533%0.33227%0.273SS..Hα-helixtrans-77.7-26178.2-71.5168.3-157.400113.3N295 T296 M316 V318 P322N295-E320 WeakPolarHBondContact CA-OE1 3.39Å; N295-E320 WeakPolarHBondContact CB-OE1 3.16Å; T296-E320 WeakPolarHBondContact CB-OE2 3.26Å; T296-E320 WeakPolarHBondContact CG2-OE2 3.43Å; T296-E320 PolarHBondContact N-OE1 3.03Å; T296-E320 PolarHBondContact OG1-OE2 3.09Å; M316-E320 WeakPolarHBondContact O-CB 3.44Å; M316-E320 VanDerWaalsContact O-CG 3.3Å; M316-E320 WeakPolarHBondContact O-CG 3.27Å; M316-E320 PolarHBondContact O-N 2.89Å; V318-E320 VanDerWaalsContact C-N 3.27Å; V318-E320 PolarHBondContact O-N 3.11Å; E320-P322 VanDerWaalsContact C-CD 3.43Å
321N97.7Very high97.8Very high40 Ų4048.4 Ų48.421%0.21428%0.283CS..  trans-129.849.8-172.4-55.6-87.6000113.2L317 V318 N323 L324 V325 V379L317-N321 WeakPolarHBondContact O-CB 3.46Å; L317-N321 PolarHBondContact O-N 3.39Å; L317-N321 VanDerWaalsContact O-N 3.11Å; L317-N321 PolarHBondContact O-ND2 2.93Å; V318-N321 CarbonylContact O-C 3.59Å; V318-N321 PolarHBondContact O-N 3.31Å; N321-N323 PolarHBondContact O-N 2.66Å; N321-L324 PolarHBondContact O-N 3.45Å; N321-V325 HydrophobicContact CB-CB 4.27Å; N321-V325 HydrophobicContact CB-CG2 3.75Å; N321-V325 PolarHBondContact O-N 3.13Å; N321-V379 HydrophobicContact CB-CG1 4.32Å
322P97.6Very high97.8Very high91 Ų9152.8 Ų52.859%0.59131%0.305SS*.THydrogen-bonded Turntrans-66.4-19-166.927.3-37.1000114.7V318 E320V318-P322 WeakPolarHBondContact O-CA 3.38Å; E320-P322 VanDerWaalsContact C-CD 3.43Å
323N96.4Very high97.9Very high159 Ų15950 Ų5085%0.8529%0.285SS*.THydrogen-bonded Turntrans-88.2-9.6178.3-64.6-36.2000113.6N321N321-N323 PolarHBondContact O-N 2.66Å
324L98Very high97.8Very high19 Ų1955.3 Ų55.310%0.09931%0.306CS..THydrogen-bonded Turntrans-122.4-36.6-176.4-178.664.5000111.8N321 F344 S345 T346 V379 Y382 L392N321-L324 PolarHBondContact O-N 3.45Å; L324-F344 CarbonylContact O-C 3.58Å; L324-F344 VanDerWaalsContact O-CA 3.29Å; L324-F344 WeakPolarHBondContact O-CA 3.43Å; L324-S345 PolarHBondContact O-N 3.46Å; L324-T346 HydrophobicContact CD1-CG2 4Å; L324-V379 HydrophobicContact CD2-CG1 4.28Å; L324-Y382 HydrophobicContact CD1-CD1 4.12Å; L324-Y382 HydrophobicContact CD1-CE1 4.16Å; L324-Y382 HydrophobicContact CD1-CG 4.37Å; L324-Y382 HydrophobicContact CD2-CD1 3.66Å; L324-Y382 HydrophobicContact CD2-CE1 4.41Å; L324-Y382 HydrophobicContact CD2-CG 3.93Å; L324-L392 HydrophobicContact CD1-CD1 4.39Å
325V98.8Very high97.3Very high4 Ų459.5 Ų59.52%0.02433%0.326CS..EExtended strand (participates in β ladder)trans-117.8134.1-171.7-166.70000110.6L317 V318 N321 L342 K343 F344 V379L317-V325 HydrophobicContact CD2-CG1 4.38Å; V318-V325 HydrophobicContact CG2-CG1 3.93Å; N321-V325 HydrophobicContact CB-CB 4.27Å; N321-V325 HydrophobicContact CB-CG2 3.75Å; N321-V325 PolarHBondContact O-N 3.13Å; V325-L342 HydrophobicContact CG1-CD2 4Å; V325-K343 WeakPolarHBondContact CA-O 3.46Å; V325-F344 HydrophobicContact CG1-CD1 4.35Å; V325-F344 HydrophobicContact CG1-CE1 4.08Å; V325-F344 HydrophobicContact CG1-CZ 4.47Å; V325-F344 HydrophobicContact CG2-CD1 3.61Å; V325-F344 HydrophobicContact CG2-CE1 3.68Å; V325-V379 HydrophobicContact CG2-CG1 3.5Å
326S98.7Very high97.1Very high50 Ų5057.3 Ų57.335%0.3532%0.323SS..EExtended strand (participates in β ladder)trans-133.7152169.751.40000110.1K343S326-K343 PolarHBondContact N-O 3.32Å; S326-K343 PolarHBondContact O-N 2.84Å
327K98.4Very high97Very high67 Ų6758 Ų5829%0.29132%0.324SS..EExtended strand (participates in β ladder)trans-103.4125.4174.2-176.417266.3171.60109.7Q314 D315 V318 N340 L342Q314-K327 HydrophobicContact CB-CD 4.11Å; D315-K327 WeakPolarHBondContact OD1-CE 3.46Å; D315-K327 IonicContact OD1-NZ 2.87Å; D315-K327 PolarHBondContact OD1-NZ 3.47Å; D315-K327 IonicContact OD2-NZ 2.75Å; D315-K327 PolarHBondContact OD2-NZ 2.9Å; D315-K327 VanDerWaalsContact OD2-NZ 3.08Å; V318-K327 HydrophobicContact CG2-CB 3.97Å; K327-N340 HydrophobicContact CD-CB 4.11Å; K327-N340 HydrophobicContact CG-CB 4.28Å; K327-L342 HydrophobicContact CB-CD2 4.4Å
328I98.2Very high97Very high51 Ų5160.2 Ų60.226%0.26234%0.339SS..EExtended strand (participates in β ladder)trans-112137.8178.9-54.7173.6000108.1I330 V341 K343 F398I328-I330 HydrophobicContact CG2-CG2 4.15Å; I328-V341 PolarHBondContact N-O 2.78Å; I328-V341 PolarHBondContact O-N 3.41Å; I328-K343 HydrophobicContact CD1-CB 3.76Å; I328-K343 HydrophobicContact CD1-CD 3.95Å; I328-K343 HydrophobicContact CD1-CG 4.4Å; I328-K343 HydrophobicContact CG1-CB 4.36Å; I328-F398 HydrophobicContact CD1-CD1 4.43Å; I328-F398 HydrophobicContact CD1-CE1 3.85Å
329V98.7Very high97Very high85 Ų8558.6 Ų58.652%0.51533%0.329SS..EExtended strand (participates in β ladder)trans-101.1112.9170.8-177.70000108G331 P338 L339V329-G331 VanDerWaalsContact CG1-O 3.26Å; V329-G331 WeakPolarHBondContact CG1-O 3.28Å; V329-P338 HydrophobicContact CG1-CB 4.02Å; V329-P338 HydrophobicContact CG2-CB 4.43Å; V329-L339 WeakPolarHBondContact CA-O 3.46Å
330I98.6Very high97.1Very high28 Ų2855.2 Ų55.214%0.14430%0.3CS..EExtended strand (participates in β ladder)trans-91-6.6-176.964.2164.9000113.2I328 L339 V341 W355 S470 I471 F474I328-I330 HydrophobicContact CG2-CG2 4.15Å; I330-L339 HydrophobicContact CD1-CB 4.45Å; I330-L339 HydrophobicContact CG1-CB 3.72Å; I330-L339 PolarHBondContact N-O 3Å; I330-V341 HydrophobicContact CB-CG2 4.49Å; I330-V341 HydrophobicContact CD1-CG2 3.9Å; I330-V341 HydrophobicContact CG1-CG2 4.02Å; I330-V341 HydrophobicContact CG2-CB 4.36Å; I330-V341 HydrophobicContact CG2-CG2 3.68Å; I330-W355 HydrophobicContact CD1-CH2 4.03Å; I330-S470 PolarHBondContact O-OG 3.34Å; I330-I471 HydrophobicContact CD1-CG1 4.06Å; I330-F474 HydrophobicContact CB-CD2 4.45Å; I330-F474 HydrophobicContact CG2-CB 4.39Å; I330-F474 HydrophobicContact CG2-CD2 3.54Å; I330-F474 HydrophobicContact CG2-CE2 4.09Å; I330-F474 HydrophobicContact CG2-CG 4.11Å
331G98.5Very high97.1Very high20 Ų2051.8 Ų51.821%0.20628%0.284CS..EExtended strand (participates in β ladder)trans163-158.2178.300000111.8V329 L339 S470V329-G331 VanDerWaalsContact CG1-O 3.26Å; V329-G331 WeakPolarHBondContact CG1-O 3.28Å; G331-L339 PolarHBondContact O-N 3.21Å; G331-S470 WeakPolarHBondContact CA-OG 3.38Å
332Q97.8Very high97.2Very high126 Ų12649.9 Ų49.959%0.58927%0.274SS*.EExtended strand (participates in β ladder)trans-132.1146.5176.7-64.9178.5900109.1R337 S466Q332-R337 CarbonylContact C-O 3.49Å; Q332-R337 VanDerWaalsContact CA-O 3.25Å; Q332-R337 WeakPolarHBondContact CA-O 2.94Å; Q332-S466 WeakPolarHBondContact O-CB 3.04Å
333S97.6Very high97.3Very high6 Ų647.6 Ų47.64%0.04225%0.254CS..  trans-67.5175168.867.60000111.8E335 G336 R337 D406 E467S333-E335 VanDerWaalsContact C-N 3.31Å; S333-E335 PolarHBondContact O-N 3.36Å; S333-G336 PolarHBondContact O-N 2.91Å; S333-R337 PolarHBondContact N-O 3.4Å; S333-R337 WeakPolarHBondContact OG-CB 3.38Å; S333-R337 PolarHBondContact OG-N 3.48Å; S333-R337 PolarHBondContact OG-O 3.26Å; S333-D406 VanDerWaalsContact CB-CG 3.44Å; S333-D406 VanDerWaalsContact CB-OD1 3.23Å; S333-D406 WeakPolarHBondContact CB-OD1 3.39Å; S333-D406 VanDerWaalsContact CB-OD2 3.26Å; S333-D406 WeakPolarHBondContact CB-OD2 3.08Å; S333-D406 PolarHBondContact OG-OD1 3.2Å; S333-D406 PolarHBondContact OG-OD2 3.3Å; S333-D406 VanDerWaalsContact OG-OD2 3.11Å; S333-E467 WeakPolarHBondContact CA-OE1 2.95Å; S333-E467 VanDerWaalsContact CB-OE1 3.24Å; S333-E467 WeakPolarHBondContact CB-OE1 3.45Å
334Y93.6Very high97.4Very high112 Ų11240 Ų4044%0.43921%0.214SC..THydrogen-bonded Turntrans-58.8-41.9179.1180-96.9000112.8G336 D406 K423 P424 S466 E467Y334-G336 PolarHBondContact O-N 3.09Å; Y334-D406 PolarHBondContact N-OD2 3.13Å; Y334-K423 HydrophobicContact CD1-CB 4.3Å; Y334-K423 HydrophobicContact CD2-CB 3.85Å; Y334-K423 HydrophobicContact CD2-CD 4Å; Y334-K423 HydrophobicContact CD2-CG 3.62Å; Y334-K423 HydrophobicContact CE2-CB 4.28Å; Y334-K423 HydrophobicContact CE2-CD 4.27Å; Y334-K423 HydrophobicContact CE2-CG 3.67Å; Y334-K423 HydrophobicContact CG-CB 3.86Å; Y334-K423 HydrophobicContact CG-CG 4.16Å; Y334-P424 HydrophobicContact CE1-CG 4.1Å; Y334-P424 VanDerWaalsContact OH-CD 3.28Å; Y334-P424 WeakPolarHBondContact OH-CD 3.31Å; Y334-S466 PolarHBondContact N-OG 3.4Å; Y334-E467 PolarHBondContact N-OE1 3.04Å
335E88.9Confident97.4Very high89 Ų8939.8 Ų39.842%0.41621%0.214SC..THydrogen-bonded Turntrans-85.112.1178.4-59.9-178.9169.700112.8S333 R337 D406 R422S333-E335 VanDerWaalsContact C-N 3.31Å; S333-E335 PolarHBondContact O-N 3.36Å; E335-R337 IonicContact OE2-CZ 3.95Å; E335-R337 IonicContact OE2-NH1 3.12Å; E335-R337 PolarHBondContact OE2-NH1 3.49Å; E335-R337 IonicContact OE2-NH2 3.98Å; E335-R337 PolarHBondContact OE2-NH2 3.48Å; E335-D406 WeakPolarHBondContact CB-OD2 3.41Å; E335-D406 HydrophobicContact CG-CB 4.37Å; E335-D406 WeakPolarHBondContact CG-OD2 3.28Å; E335-D406 PolarHBondContact N-OD2 3.33Å; E335-R422 HydrophobicContact CG-CB 4.4Å; E335-R422 WeakPolarHBondContact OE1-CB 3.39Å; E335-R422 IonicContact OE1-NE 2.77Å
336G92.4Very high97.4Very high39 Ų3942 Ų4240%0.40223%0.227SC..SBendtrans83.316.6170.700000115.5S333 Y334S333-G336 PolarHBondContact O-N 2.91Å; Y334-G336 PolarHBondContact O-N 3.09Å
337R96.5Very high97.1Very high47 Ų4741.3 Ų41.318%0.17723%0.228CC..  trans-80140.5175-59-174.7179.671.9-0.4110.1L307 Q332 S333 E335 L339 P405 D406 Y409L307-R337 VanDerWaalsContact CD2-CD 3.46Å; Q332-R337 CarbonylContact C-O 3.49Å; Q332-R337 VanDerWaalsContact CA-O 3.25Å; Q332-R337 WeakPolarHBondContact CA-O 2.94Å; S333-R337 PolarHBondContact N-O 3.4Å; S333-R337 WeakPolarHBondContact OG-CB 3.38Å; S333-R337 PolarHBondContact OG-N 3.48Å; S333-R337 PolarHBondContact OG-O 3.26Å; E335-R337 IonicContact OE2-CZ 3.95Å; E335-R337 IonicContact OE2-NH1 3.12Å; E335-R337 PolarHBondContact OE2-NH1 3.49Å; E335-R337 IonicContact OE2-NH2 3.98Å; E335-R337 PolarHBondContact OE2-NH2 3.48Å; R337-L339 PolarHBondContact O-N 3.34Å; R337-P405 HydrophobicContact CB-CB 4.33Å; R337-P405 HydrophobicContact CB-CG 4.22Å; R337-D406 IonicContact CZ-OD1 3.39Å; R337-D406 VanDerWaalsContact NH1-CG 3.35Å; R337-D406 IonicContact NH1-OD1 3.6Å; R337-D406 PolarHBondContact NH1-OD1 3.19Å; R337-Y409 VanDerWaalsContact NH2-CG 3.32Å
338P97.2Very high96.8Very high48 Ų4841.4 Ų41.431%0.31225%0.248SC..EExtended strand (participates in β ladder)trans-67.7135.518028.6-35.3000111.4Y311 V329 N340Y311-P338 HydrophobicContact CE2-CG 3.82Å; Y311-P338 PolarHBondContact OH-O 2.96Å; V329-P338 HydrophobicContact CG1-CB 4.02Å; V329-P338 HydrophobicContact CG2-CB 4.43Å; P338-N340 PolarHBondContact O-N 3.44Å
339L98.8Very high96.4Very high0 Ų044.5 Ų44.50%028%0.275CS..EExtended strand (participates in β ladder)trans-86.793.6172.2-59.7174.6000108.7V329 I330 G331 R337 P405 E467V329-L339 WeakPolarHBondContact CA-O 3.46Å; I330-L339 HydrophobicContact CD1-CB 4.45Å; I330-L339 HydrophobicContact CG1-CB 3.72Å; I330-L339 PolarHBondContact N-O 3Å; G331-L339 PolarHBondContact O-N 3.21Å; R337-L339 PolarHBondContact O-N 3.34Å; L339-P405 HydrophobicContact CD2-CG 3.77Å; L339-E467 HydrophobicContact CD2-CG 4.25Å
340N98.7Very high96.1Very high7 Ų744.8 Ų44.84%0.03727%0.273CS..EExtended strand (participates in β ladder)trans-90.6123.1-172-67.6-33000111.6Y311 Q314 K327 P338Y311-N340 WeakPolarHBondContact CD1-ND2 3.42Å; Y311-N340 WeakPolarHBondContact CE1-ND2 3.44Å; Q314-N340 VanDerWaalsContact OE1-CB 3.27Å; Q314-N340 PolarHBondContact OE1-ND2 3.15Å; K327-N340 HydrophobicContact CD-CB 4.11Å; K327-N340 HydrophobicContact CG-CB 4.28Å; P338-N340 PolarHBondContact O-N 3.44Å
341V98.9Very high96Very high0 Ų044.8 Ų44.80%027%0.271CS..EExtended strand (participates in β ladder)trans-115127.7174.5-177.10000109.5I328 I330 W355 F398 E400I328-V341 PolarHBondContact N-O 2.78Å; I328-V341 PolarHBondContact O-N 3.41Å; I330-V341 HydrophobicContact CB-CG2 4.49Å; I330-V341 HydrophobicContact CD1-CG2 3.9Å; I330-V341 HydrophobicContact CG1-CG2 4.02Å; I330-V341 HydrophobicContact CG2-CB 4.36Å; I330-V341 HydrophobicContact CG2-CG2 3.68Å; V341-W355 HydrophobicContact CG1-CH2 4.43Å; V341-W355 HydrophobicContact CG1-CZ3 4.19Å; V341-W355 HydrophobicContact CG2-CH2 3.85Å; V341-W355 HydrophobicContact CG2-CZ3 4.27Å; V341-F398 HydrophobicContact CG1-CB 3.86Å; V341-F398 HydrophobicContact CG1-CD1 3.98Å; V341-F398 HydrophobicContact CG1-CG 4.41Å; V341-E400 HydrophobicContact CG2-CB 4.14Å; V341-E400 HydrophobicContact CG2-CG 4.16Å
342L98.9Very high95.9Very high0 Ų045.6 Ų45.60%027%0.273CS..EExtended strand (participates in β ladder)trans-82.3124.3168.7-68.5174.7000109.3Q314 L317 V318 V325 K327 F344 A375 F398 L399 I401Q314-L342 HydrophobicContact CB-CD2 4.08Å; Q314-L342 HydrophobicContact CG-CD1 4.16Å; Q314-L342 HydrophobicContact CG-CD2 4.23Å; Q314-L342 HydrophobicContact CG-CG 4.21Å; L317-L342 HydrophobicContact CD2-CD1 3.82Å; V318-L342 HydrophobicContact CG2-CD2 4.02Å; V325-L342 HydrophobicContact CG1-CD2 4Å; K327-L342 HydrophobicContact CB-CD2 4.4Å; L342-F344 HydrophobicContact CB-CE2 3.8Å; L342-F344 HydrophobicContact CB-CZ 4.07Å; L342-F344 HydrophobicContact CD1-CZ 4.16Å; L342-A375 HydrophobicContact CD1-CB 3.9Å; L342-F398 CarbonylContact O-C 3.6Å; L342-F398 WeakPolarHBondContact O-CA 3.42Å; L342-L399 HydrophobicContact CB-CB 4.48Å; L342-L399 PolarHBondContact N-O 2.48Å; L342-L399 PolarHBondContact O-N 2.98Å; L342-I401 HydrophobicContact CD1-CD1 4.04Å
343K98.8Very high96Very high43 Ų4339.6 Ų39.619%0.18725%0.245CC..EExtended strand (participates in β ladder)trans-101.7120.6171.1175.3-179178.2157.40109.4V325 S326 I328 D396 I397 F398V325-K343 WeakPolarHBondContact CA-O 3.46Å; S326-K343 PolarHBondContact N-O 3.32Å; S326-K343 PolarHBondContact O-N 2.84Å; I328-K343 HydrophobicContact CD1-CB 3.76Å; I328-K343 HydrophobicContact CD1-CD 3.95Å; I328-K343 HydrophobicContact CD1-CG 4.4Å; I328-K343 HydrophobicContact CG1-CB 4.36Å; K343-D396 WeakPolarHBondContact CE-OD2 3.25Å; K343-D396 IonicContact NZ-OD2 2.95Å; K343-D396 PolarHBondContact NZ-OD2 3.47Å; K343-I397 WeakPolarHBondContact CA-O 3.46Å; K343-F398 HydrophobicContact CB-CD1 3.9Å; K343-F398 HydrophobicContact CB-CE1 3.73Å; K343-F398 HydrophobicContact CD-CE1 3.67Å; K343-F398 HydrophobicContact CD-CZ 4.01Å; K343-F398 HydrophobicContact CG-CD1 4.11Å; K343-F398 HydrophobicContact CG-CE1 3.59Å; K343-F398 HydrophobicContact CG-CZ 4.15Å
344F98.8Very high96Very high0 Ų039.3 Ų39.30%024%0.243CC..EExtended strand (participates in β ladder)trans-101117.6169.8-54.1-95000109.1L317 L324 V325 L342 A375 I378 V379 L392 D396 I397 L399L317-F344 HydrophobicContact CD2-CE1 4.28Å; L317-F344 HydrophobicContact CD2-CZ 4.28Å; L324-F344 CarbonylContact O-C 3.58Å; L324-F344 VanDerWaalsContact O-CA 3.29Å; L324-F344 WeakPolarHBondContact O-CA 3.43Å; V325-F344 HydrophobicContact CG1-CD1 4.35Å; V325-F344 HydrophobicContact CG1-CE1 4.08Å; V325-F344 HydrophobicContact CG1-CZ 4.47Å; V325-F344 HydrophobicContact CG2-CD1 3.61Å; V325-F344 HydrophobicContact CG2-CE1 3.68Å; L342-F344 HydrophobicContact CB-CE2 3.8Å; L342-F344 HydrophobicContact CB-CZ 4.07Å; L342-F344 HydrophobicContact CD1-CZ 4.16Å; F344-A375 HydrophobicContact CZ-CB 4.02Å; F344-I378 HydrophobicContact CB-CG2 4.19Å; F344-I378 HydrophobicContact CD1-CB 4.09Å; F344-I378 HydrophobicContact CD1-CG2 3.41Å; F344-I378 VanDerWaalsContact CD1-CG2 3.41Å; F344-I378 HydrophobicContact CD2-CD1 4.03Å; F344-I378 HydrophobicContact CD2-CG2 4.49Å; F344-I378 HydrophobicContact CE1-CB 4.03Å; F344-I378 HydrophobicContact CE1-CD1 4.37Å; F344-I378 HydrophobicContact CE1-CG2 3.88Å; F344-I378 HydrophobicContact CE2-CD1 3.85Å; F344-I378 HydrophobicContact CG-CD1 4.39Å; F344-I378 HydrophobicContact CG-CG2 3.78Å; F344-I378 HydrophobicContact CZ-CB 4.48Å; F344-I378 HydrophobicContact CZ-CD1 4.04Å; F344-V379 HydrophobicContact CD1-CG1 4.23Å; F344-V379 HydrophobicContact CE1-CG1 3.86Å; F344-L392 HydrophobicContact CB-CD2 3.78Å; F344-D396 WeakPolarHBondContact O-CA 3.3Å; F344-I397 HydrophobicContact CB-CB 4.24Å; F344-I397 HydrophobicContact CD2-CB 4.25Å; F344-I397 HydrophobicContact CD2-CG2 4.29Å; F344-I397 PolarHBondContact N-O 2.78Å; F344-I397 PolarHBondContact O-N 3.29Å; F344-L399 HydrophobicContact CE2-CB 3.94Å; F344-L399 HydrophobicContact CE2-CD2 4.24Å
345S98.5Very high96.3Very high13 Ų1334 Ų349%0.09122%0.222CC..  trans-155.2145.6-173.9-176.20000111.8L324 G347 D396L324-S345 PolarHBondContact O-N 3.46Å; S345-G347 PolarHBondContact OG-N 3.02Å; S345-G347 PolarHBondContact OG-O 3.08Å; S345-D396 WeakPolarHBondContact CB-OD1 3.46Å; S345-D396 PolarHBondContact OG-OD1 2.79Å
346T97.9Very high96.8Very high50 Ų5029.9 Ų29.931%0.30720%0.203SC..SBendtrans-100.416.917455.30000112.2L324 R351 Y382 L392L324-T346 HydrophobicContact CD1-CG2 4Å; T346-R351 PolarHBondContact OG1-NH1 3.29Å; T346-R351 PolarHBondContact OG1-NH2 3.49Å; T346-Y382 HydrophobicContact CG2-CE1 4.34Å; T346-Y382 HydrophobicContact CG2-CE2 3.78Å; T346-Y382 VanDerWaalsContact CG2-CZ 3.49Å; T346-Y382 WeakPolarHBondContact CG2-OH 3.49Å; T346-L392 HydrophobicContact CG2-CB 4.45Å; T346-L392 VanDerWaalsContact CG2-O 3.24Å; T346-L392 WeakPolarHBondContact CG2-O 3.34Å; T346-L392 PolarHBondContact OG1-O 3.47Å
347G92.9Very high97.1Very high37 Ų3728 Ų2838%0.38118%0.183SC..SBendtrans104.2-163.5179.700000113.1S345 R351S345-G347 PolarHBondContact OG-N 3.02Å; S345-G347 PolarHBondContact OG-O 3.08Å; G347-R351 WeakPolarHBondContact O-CD 3.32Å; G347-R351 PolarHBondContact O-NH1 2.94Å
348G92.2Very high97.2Very high68 Ų6825.8 Ų25.870%0.70118%0.175SC*.  trans83.5171.8-172.700000113.3
349S90.9Very high97.3Very high117 Ų11723.5 Ų23.582%0.81816%0.16SC*.SBendtrans-120131.7-179.7-174.70000110R351S349-R351 VanDerWaalsContact C-N 3.3Å; S349-R351 PolarHBondContact O-N 2.9Å
350N90.8Very high97.3Very high90 Ų9023.5 Ų23.548%0.48116%0.16SC..SBendtrans46.747.3178.7-16423000114.3H478 N480N350-H478 PolarHBondContact OD1-O 3.46Å; N350-N480 PolarHBondContact O-ND2 3.26Å; N350-N480 WeakPolarHBondContact OD1-CB 3.24Å
351R96.6Very high97.3Very high29 Ų2923.3 Ų23.311%0.10916%0.159CC..  trans-66.4154.4178.2-77.1168.961.9179.1-10.5111.1T346 G347 S349 A353 L392 N393 N394 M395 D396 H478T346-R351 PolarHBondContact OG1-NH1 3.29Å; T346-R351 PolarHBondContact OG1-NH2 3.49Å; G347-R351 WeakPolarHBondContact O-CD 3.32Å; G347-R351 PolarHBondContact O-NH1 2.94Å; S349-R351 VanDerWaalsContact C-N 3.3Å; S349-R351 PolarHBondContact O-N 2.9Å; R351-A353 PolarHBondContact O-N 3.37Å; R351-L392 PolarHBondContact NH2-O 2.96Å; R351-N393 PolarHBondContact NH2-O 2.83Å; R351-N394 PolarHBondContact NE-O 3.3Å; R351-M395 PolarHBondContact NH2-O 2.96Å; R351-D396 IonicContact CZ-OD1 3.82Å; R351-D396 IonicContact NE-OD1 2.84Å; R351-H478 PolarHBondContact O-CE1 3.21Å
352P98.1Very high97.2Very high37 Ų3723.3 Ų23.324%0.2416%0.159CC..  trans-51.5134.8167.1-23.734.2000109.8M395 D396 N480 K482P352-M395 HydrophobicContact CB-CE 3.88Å; P352-M395 HydrophobicContact CB-CG 4.33Å; P352-M395 CarbonylContact O-C 3.49Å; P352-M395 WeakPolarHBondContact O-CA 3.33Å; P352-M395 VanDerWaalsContact O-CB 3.26Å; P352-M395 WeakPolarHBondContact O-CB 3.33Å; P352-D396 PolarHBondContact O-N 2.89Å; P352-N480 CarbonylContact C-O 3.52Å; P352-N480 WeakPolarHBondContact CA-O 3.45Å; P352-K482 HydrophobicContact CB-CG 3.81Å
353A98.6Very high97.1Very high0 Ų023.5 Ų23.50%016%0.16CC..EExtended strand (participates in β ladder)trans-128.6156.3-172.200000113.5R351 D396 F398 N480 I481 K482R351-A353 PolarHBondContact O-N 3.37Å; A353-D396 CarbonylContact C-O 3.43Å; A353-D396 WeakPolarHBondContact CA-O 3.27Å; A353-D396 HydrophobicContact CB-CB 4.16Å; A353-F398 HydrophobicContact CB-CD2 3.84Å; A353-F398 HydrophobicContact CB-CE2 3.59Å; A353-N480 PolarHBondContact N-O 3.47Å; A353-I481 HydrophobicContact CB-CG1 4.26Å; A353-I481 CarbonylContact O-C 3.6Å; A353-I481 WeakPolarHBondContact O-CA 3.17Å; A353-K482 PolarHBondContact O-N 3.46Å
354I98.9Very high97.1Very high0 Ų021.6 Ų21.60%015%0.152CC..EExtended strand (participates in β ladder)trans-113.1129.9170.1-65.7149.9000107.4I356 I391 M395 D396 I397 F398 A483 I485 M593 T596I354-I356 HydrophobicContact CG2-CD1 4.46Å; I354-I356 HydrophobicContact CG2-CG1 4.11Å; I354-I391 HydrophobicContact CD1-CG2 3.98Å; I354-M395 HydrophobicContact CD1-CE 4.05Å; I354-M395 HydrophobicContact CD1-SD 3.95Å; I354-M395 HydrophobicContact CG1-CE 3.85Å; I354-M395 HydrophobicContact CG1-SD 4.41Å; I354-D396 PolarHBondContact N-O 3.03Å; I354-I397 HydrophobicContact CB-CG1 4.46Å; I354-I397 HydrophobicContact CD1-CG1 4.49Å; I354-I397 CarbonylContact O-C 3.6Å; I354-I397 WeakPolarHBondContact O-CA 3.36Å; I354-F398 PolarHBondContact O-N 2.76Å; I354-A483 HydrophobicContact CG1-CB 4.17Å; I354-A483 HydrophobicContact CG2-CB 4.29Å; I354-I485 HydrophobicContact CG2-CD1 4.08Å; I354-M593 HydrophobicContact CD1-CB 3.86Å; I354-M593 HydrophobicContact CD1-CG 3.77Å; I354-M593 HydrophobicContact CD1-SD 4.22Å; I354-M593 HydrophobicContact CG2-CG 4.16Å; I354-M593 HydrophobicContact CG2-SD 4.39Å; I354-T596 HydrophobicContact CG1-CG2 4.3Å
355W98.9Very high97.1Very high0 Ų022 Ų220%015%0.153CC..EExtended strand (participates in β ladder)trans-103.4134.4172.8177.7-79000110.3I330 V341 D357 F398 E400 I471 F474 I481 A483 F484 I485I330-W355 HydrophobicContact CD1-CH2 4.03Å; V341-W355 HydrophobicContact CG1-CH2 4.43Å; V341-W355 HydrophobicContact CG1-CZ3 4.19Å; V341-W355 HydrophobicContact CG2-CH2 3.85Å; V341-W355 HydrophobicContact CG2-CZ3 4.27Å; W355-D357 PolarHBondContact NE1-OD2 2.92Å; W355-F398 HydrophobicContact CD2-CB 4.49Å; W355-F398 HydrophobicContact CE3-CB 3.74Å; W355-F398 HydrophobicContact CE3-CG 4.43Å; W355-F398 HydrophobicContact CZ3-CB 4.19Å; W355-E400 HydrophobicContact CH2-CB 4.34Å; W355-E400 HydrophobicContact CZ2-CB 3.96Å; W355-E400 WeakPolarHBondContact CZ2-OE2 3.37Å; W355-I471 HydrophobicContact CH2-CG1 4.33Å; W355-I471 HydrophobicContact CH2-CG2 4.21Å; W355-I471 HydrophobicContact CZ2-CB 4.47Å; W355-I471 HydrophobicContact CZ2-CD1 4.24Å; W355-I471 HydrophobicContact CZ2-CG1 3.97Å; W355-I471 HydrophobicContact CZ2-CG2 3.78Å; W355-F474 AromaticContact CE3-CD1 3.82Å; W355-F474 HydrophobicContact CE3-CD1 3.82Å; W355-F474 AromaticContact CE3-CE1 3.74Å; W355-F474 HydrophobicContact CE3-CE1 3.74Å; W355-F474 HydrophobicContact CH2-CD1 4.33Å; W355-F474 AromaticContact CZ3-CD1 3.37Å; W355-F474 HydrophobicContact CZ3-CD1 3.37Å; W355-F474 AromaticContact CZ3-CE1 3.52Å; W355-F474 HydrophobicContact CZ3-CE1 3.52Å; W355-F474 HydrophobicContact CZ3-CG 4.11Å; W355-F474 HydrophobicContact CZ3-CZ 4.35Å; W355-I481 HydrophobicContact CB-CG2 4.06Å; W355-A483 PolarHBondContact N-O 2.99Å; W355-F484 HydrophobicContact CB-CD2 3.76Å; W355-F484 HydrophobicContact CB-CE2 4.16Å; W355-F484 HydrophobicContact CB-CG 4.21Å; W355-F484 AromaticContact CD1-CD1 3.79Å; W355-F484 AromaticContact CD1-CD2 3.5Å; W355-F484 AromaticContact CD1-CE1 3.48Å; W355-F484 VanDerWaalsContact CD1-CE1 3.48Å; W355-F484 AromaticContact CD1-CE2 3.2Å; W355-F484 AromaticContact CD1-CG 3.79Å; W355-F484 AromaticContact CD1-CZ 3.19Å; W355-F484 HydrophobicContact CD2-CE2 4.01Å; W355-F484 HydrophobicContact CD2-CZ 4.44Å; W355-F484 AromaticContact CE2-CE2 3.99Å; W355-F484 AromaticContact CE2-CZ 4Å; W355-F484 AromaticContact CG-CD2 3.65Å; W355-F484 HydrophobicContact CG-CD2 3.65Å; W355-F484 HydrophobicContact CG-CE1 4.5Å; W355-F484 AromaticContact CG-CE2 3.53Å; W355-F484 HydrophobicContact CG-CE2 3.53Å; W355-F484 HydrophobicContact CG-CG 4.22Å; W355-F484 AromaticContact CG-CZ 3.99Å; W355-F484 HydrophobicContact CG-CZ 3.99Å; W355-F484 AromaticContact NE1-CE1 3.71Å; W355-F484 AromaticContact NE1-CE2 3.49Å; W355-F484 AromaticContact NE1-CZ 3.17Å; W355-F484 WeakPolarHBondContact O-CA 3.36Å; W355-I485 PolarHBondContact O-N 3.44Å
356I98.9Very high97.1Very high2 Ų221.6 Ų21.61%0.0115%0.15CC..EExtended strand (participates in β ladder)trans-131.5127.9173-52.5175.3000108.1I354 I397 F398 L399 E400 I485 I487 L589 M593I354-I356 HydrophobicContact CG2-CD1 4.46Å; I354-I356 HydrophobicContact CG2-CG1 4.11Å; I356-I397 HydrophobicContact CD1-CG2 4.24Å; I356-F398 PolarHBondContact N-O 3.49Å; I356-L399 HydrophobicContact CB-CD1 3.85Å; I356-L399 HydrophobicContact CG2-CD1 3.75Å; I356-L399 CarbonylContact O-C 3.58Å; I356-L399 VanDerWaalsContact O-CA 3.28Å; I356-L399 WeakPolarHBondContact O-CA 3.41Å; I356-E400 PolarHBondContact O-N 2.81Å; I356-I485 VanDerWaalsContact CA-O 3.31Å; I356-I485 WeakPolarHBondContact CA-O 3.08Å; I356-I485 HydrophobicContact CG1-CB 4.43Å; I356-I485 HydrophobicContact CG1-CD1 4.2Å; I356-I487 HydrophobicContact CG2-CD1 3.73Å; I356-I487 HydrophobicContact CG2-CG1 4.39Å; I356-L589 HydrophobicContact CD1-CD2 4.49Å; I356-M593 HydrophobicContact CD1-SD 4.38Å
357D98.9Very high97.2Very high0 Ų019.2 Ų19.20%014%0.136CC..EExtended strand (participates in β ladder)trans-125.4149.7171.16090.3000112.5W355 E400 T403 F484 I485 S486 I487W355-D357 PolarHBondContact NE1-OD2 2.92Å; D357-E400 WeakPolarHBondContact CA-O 3.3Å; D357-E400 HydrophobicContact CB-CB 4.21Å; D357-T403 WeakPolarHBondContact CB-OG1 3.37Å; D357-F484 WeakPolarHBondContact OD2-CE1 3.04Å; D357-F484 WeakPolarHBondContact OD2-CZ 3.2Å; D357-I485 PolarHBondContact N-O 3.23Å; D357-S486 WeakPolarHBondContact OD1-CA 3.48Å; D357-S486 WeakPolarHBondContact OD1-CB 3.39Å; D357-S486 PolarHBondContact OD1-OG 3.41Å; D357-I487 WeakPolarHBondContact O-CB 3.49Å; D357-I487 PolarHBondContact O-N 3.18Å
358T98.9Very high97.5Very high0 Ų017.5 Ų17.50%012%0.118CC..EExtended strand (participates in β ladder)trans-131.4151.2175.354.80000110.4I360 T367 E400 I401 T403 I487T358-I360 PolarHBondContact O-N 3.39Å; T358-T367 WeakPolarHBondContact CB-O 3.5Å; T358-T367 VanDerWaalsContact CG2-O 3.22Å; T358-T367 WeakPolarHBondContact CG2-O 3.25Å; T358-E400 PolarHBondContact N-O 3.34Å; T358-E400 PolarHBondContact OG1-O 2.78Å; T358-I401 CarbonylContact O-C 3.09Å; T358-I401 VanDerWaalsContact O-O 3.12Å; T358-I401 VanDerWaalsContact OG1-C 3.25Å; T358-I401 VanDerWaalsContact OG1-CA 3.26Å; T358-I401 WeakPolarHBondContact OG1-CA 3.35Å; T358-I401 PolarHBondContact OG1-O 3.42Å; T358-T403 PolarHBondContact O-N 3.2Å; T358-T403 PolarHBondContact O-OG1 2.89Å; T358-I487 HydrophobicContact CG2-CB 3.94Å; T358-I487 HydrophobicContact CG2-CD1 4.05Å; T358-I487 HydrophobicContact CG2-CG1 4.42Å; T358-I487 HydrophobicContact CG2-CG2 4.36Å
359G98.6Very high97.8Very high0 Ų014.5 Ų14.50%09%0.086CC..  trans7228.916800000115H361 T367 N404G359-H361 CarbonylContact C-O 3.5Å; G359-H361 PolarHBondContact O-N 3.15Å; G359-T367 WeakPolarHBondContact CA-OG1 3.3Å; G359-T367 PolarHBondContact N-OG1 3.44Å; G359-N404 WeakPolarHBondContact O-CB 3.31Å; G359-N404 PolarHBondContact O-N 2.89Å
360I98.8Very high98.1Very high1 Ų18.9 Ų8.91%0.0055%0.047CC..SBendtrans-62.5-34.1169.6-167.4170.8000110.5T358 T403 N404 P435 W439 H488T358-I360 PolarHBondContact O-N 3.39Å; I360-T403 HydrophobicContact CB-CG2 3.88Å; I360-T403 HydrophobicContact CD1-CG2 4.21Å; I360-T403 HydrophobicContact CG1-CG2 3.8Å; I360-N404 WeakPolarHBondContact O-CB 3.28Å; I360-N404 PolarHBondContact O-ND2 2.99Å; I360-P435 HydrophobicContact CD1-CB 4.17Å; I360-P435 HydrophobicContact CG1-CB 3.72Å; I360-P435 HydrophobicContact CG1-CG 3.76Å; I360-P435 WeakPolarHBondContact O-CG 3.46Å; I360-W439 HydrophobicContact CD1-CZ2 4.25Å; I360-H488 WeakPolarHBondContact CG2-CE1 3.29Å
361H98.8Very high98.5Very high3 Ų34.6 Ų4.61%0.0142%0.024CC..SBendtrans-96131.6160.4-58.7137.3000110.5G359 E364 R419 D434 N436 H488G359-H361 CarbonylContact C-O 3.5Å; G359-H361 PolarHBondContact O-N 3.15Å; H361-E364 VanDerWaalsContact CB-CD 3.44Å; H361-E364 HydrophobicContact CB-CG 3.87Å; H361-E364 WeakPolarHBondContact CB-OE1 3.12Å; H361-E364 IonicContact CE1-OE1 2.69Å; H361-E364 IonicContact CG-OE1 2.66Å; H361-E364 IonicContact ND1-OE1 3.49Å; H361-E364 PolarHBondContact ND1-OE1 3.38Å; H361-E364 IonicContact ND1-OE2 3.62Å; H361-R419 WeakPolarHBondContact CA-O 3.39Å; H361-R419 HydrophobicContact CB-CG 3.96Å; H361-R419 PolarHBondContact CE1-NH1 2.81Å; H361-R419 VanDerWaalsContact CE1-NH1 3.26Å; H361-R419 PolarHBondContact CE1-NH2 3.36Å; H361-R419 VanDerWaalsContact ND1-CZ 3.34Å; H361-R419 PolarHBondContact ND1-NH1 3.38Å; H361-R419 VanDerWaalsContact NE2-CZ 3.32Å; H361-R419 PolarHBondContact NE2-NH2 2.82Å; H361-R419 VanDerWaalsContact NE2-NH2 3.13Å; H361-D434 IonicContact CD2-OD1 3.75Å; H361-D434 IonicContact NE2-OD1 3.83Å; H361-D434 PolarHBondContact NE2-OD1 3.43Å; H361-D434 VanDerWaalsContact NE2-OD1 3.08Å; H361-D434 IonicContact NE2-OD2 3.26Å; H361-N436 WeakPolarHBondContact NE2-CB 3.44Å; H361-H488 AromaticContact CE1-CE1 3.18Å; H361-H488 PolarHBondContact CE1-CE1 3.04Å; H361-H488 AromaticContact CE1-ND1 3.52Å; H361-H488 AromaticContact ND1-CE1 3.25Å; H361-H488 PolarHBondContact ND1-CE1 2.96Å; H361-H488 VanDerWaalsContact ND1-CE1 3.25Å; H361-H488 AromaticContact ND1-ND1 3.13Å; H361-H488 PolarHBondContact ND1-ND1 2.92Å; H361-H488 VanDerWaalsContact ND1-ND1 3.13Å
362S97.9Very high98.6Very high0 Ų03.4 Ų3.40%02%0.02CC..THydrogen-bonded Turntrans-75.3-35.1-165.235.10000114.5E364 W365 G407 W418 R419S362-E364 PolarHBondContact O-N 3.23Å; S362-W365 PolarHBondContact O-NE1 2.99Å; S362-G407 WeakPolarHBondContact CB-O 3.42Å; S362-W418 PolarHBondContact OG-O 3.34Å; S362-R419 PolarHBondContact N-O 2.7Å; S362-R419 VanDerWaalsContact N-O 3.15Å; S362-R419 PolarHBondContact OG-O 3.38Å; S362-R419 VanDerWaalsContact OG-O 3.08Å
363R97.3Very high98.6Very high4 Ų43.3 Ų3.32%0.0152%0.015CC..THydrogen-bonded Turntrans-68.6-12.117864.3-164.6-171.1-179.73.4115.7D231 V232 W365 R416 M417 W418 F571D231-R363 IonicContact OD1-CZ 3.08Å; D231-R363 IonicContact OD1-NH1 2.77Å; D231-R363 PolarHBondContact OD1-NH1 2.8Å; D231-R363 IonicContact OD1-NH2 2.59Å; D231-R363 IonicContact OD2-NH1 3.83Å; V232-R363 PolarHBondContact O-NH2 3.28Å; R363-W365 PolarHBondContact O-N 2.92Å; R363-R416 PolarHBondContact O-NH1 3.26Å; R363-M417 WeakPolarHBondContact CD-O 3.32Å; R363-M417 PolarHBondContact NH1-O 2.63Å; R363-W418 VanDerWaalsContact CB-O 3.26Å; R363-W418 WeakPolarHBondContact CB-O 3.35Å; R363-W418 PolarHBondContact N-O 2.85Å; R363-F571 HydrophobicContact CG-CD1 4.12Å; R363-F571 HydrophobicContact CG-CD2 4.28Å; R363-F571 HydrophobicContact CG-CE1 4.41Å; R363-F571 HydrophobicContact CG-CG 4.07Å; R363-F571 VanDerWaalsContact CZ-CE2 3.44Å; R363-F571 VanDerWaalsContact NE-CE2 3.31Å
364E98.4Very high98.6Very high3 Ų33.3 Ų3.31%0.0142%0.015CC..  trans-85.752.3-171.3-56.5179.3-17200111.9H361 S362 V366 T367 Q368 R419 H488 A489 F571H361-E364 VanDerWaalsContact CB-CD 3.44Å; H361-E364 HydrophobicContact CB-CG 3.87Å; H361-E364 WeakPolarHBondContact CB-OE1 3.12Å; H361-E364 IonicContact CE1-OE1 2.69Å; H361-E364 IonicContact CG-OE1 2.66Å; H361-E364 IonicContact ND1-OE1 3.49Å; H361-E364 PolarHBondContact ND1-OE1 3.38Å; H361-E364 IonicContact ND1-OE2 3.62Å; S362-E364 PolarHBondContact O-N 3.23Å; E364-V366 PolarHBondContact O-N 3.26Å; E364-T367 HydrophobicContact CB-CG2 4.05Å; E364-T367 WeakPolarHBondContact O-CB 3.23Å; E364-T367 VanDerWaalsContact O-CG2 3.31Å; E364-T367 WeakPolarHBondContact O-CG2 3.42Å; E364-T367 PolarHBondContact O-N 3.32Å; E364-T367 PolarHBondContact O-OG1 3.33Å; E364-Q368 PolarHBondContact O-OE1 3.14Å; E364-R419 IonicContact OE1-NH1 3.26Å; E364-R419 PolarHBondContact OE1-NH1 2.93Å; E364-H488 IonicContact OE1-ND1 3.44Å; E364-H488 WeakPolarHBondContact OE2-CA 3.44Å; E364-H488 VanDerWaalsContact OE2-CB 3.24Å; E364-H488 WeakPolarHBondContact OE2-CB 3.42Å; E364-H488 IonicContact OE2-CG 2.76Å; E364-H488 IonicContact OE2-ND1 3.57Å; E364-H488 PolarHBondContact OE2-ND1 3.29Å; E364-A489 HydrophobicContact CB-CB 4.21Å; E364-A489 WeakPolarHBondContact CG-O 3.37Å; E364-A489 PolarHBondContact OE2-N 3.37Å; E364-F571 HydrophobicContact CG-CD1 4.06Å; E364-F571 HydrophobicContact CG-CE1 4.11Å
365W98.6Very high98.6Very high7 Ų73.3 Ų3.33%0.0272%0.015CC..Hα-helixtrans-53.6-29.4-164.9-7711.4000116.2E280 M284 Y304 S362 R363 T367 Q368 A369 Y408 T411 H412 R416E280-W365 HydrophobicContact CG-CZ3 4.01Å; E280-W365 VanDerWaalsContact OE1-CZ3 3.26Å; E280-W365 WeakPolarHBondContact OE1-CZ3 3.43Å; M284-W365 HydrophobicContact CE-CH2 4.31Å; M284-W365 HydrophobicContact CE-CZ3 4.22Å; M284-W365 HydrophobicContact SD-CH2 3.98Å; M284-W365 HydrophobicContact SD-CZ3 3.51Å; M284-W365 VanDerWaalsContact SD-CZ3 3.51Å; Y304-W365 HydrophobicContact CD1-CB 3.74Å; Y304-W365 HydrophobicContact CD1-CE3 4.15Å; Y304-W365 AromaticContact CD2-CE3 3.79Å; Y304-W365 HydrophobicContact CD2-CE3 3.79Å; Y304-W365 HydrophobicContact CD2-CZ3 4.37Å; Y304-W365 VanDerWaalsContact CE1-C 3.5Å; Y304-W365 HydrophobicContact CE1-CB 3.56Å; Y304-W365 WeakPolarHBondContact CE1-O 3.42Å; Y304-W365 HydrophobicContact CE2-CE3 4.38Å; Y304-W365 HydrophobicContact CG-CB 4.41Å; Y304-W365 AromaticContact CG-CE3 3.66Å; Y304-W365 HydrophobicContact CG-CE3 3.66Å; Y304-W365 HydrophobicContact CG-CZ3 4.35Å; S362-W365 PolarHBondContact O-NE1 2.99Å; R363-W365 PolarHBondContact O-N 2.92Å; W365-T367 PolarHBondContact O-N 3.15Å; W365-Q368 PolarHBondContact O-N 3.15Å; W365-Q368 PolarHBondContact O-OE1 3.14Å; W365-A369 PolarHBondContact O-N 2.96Å; W365-A369 VanDerWaalsContact O-N 3.16Å; W365-Y408 AromaticContact CD1-CD2 3.95Å; W365-Y408 AromaticContact CD1-CE2 3.45Å; W365-Y408 VanDerWaalsContact CD1-CE2 3.45Å; W365-Y408 HydrophobicContact CG-CE2 4.06Å; W365-Y408 AromaticContact NE1-CD2 3.9Å; W365-Y408 AromaticContact NE1-CE2 3.57Å; W365-T411 PolarHBondContact NE1-OG1 3.01Å; W365-H412 AromaticContact CE2-CD2 3.76Å; W365-H412 AromaticContact CE2-NE2 3.44Å; W365-H412 AromaticContact CH2-CD2 3.93Å; W365-H412 AromaticContact CH2-CE1 3.56Å; W365-H412 AromaticContact CH2-ND1 3.89Å; W365-H412 AromaticContact CH2-NE2 3.61Å; W365-H412 AromaticContact CZ2-CD2 3.24Å; W365-H412 WeakPolarHBondContact CZ2-CD2 3.21Å; W365-H412 AromaticContact CZ2-CE1 3.63Å; W365-H412 AromaticContact CZ2-CG 3.75Å; W365-H412 AromaticContact CZ2-NE2 3.16Å; W365-H412 WeakPolarHBondContact CZ2-NE2 3.07Å; W365-H412 AromaticContact NE1-NE2 3.95Å; W365-R416 VanDerWaalsContact CE2-NE 3.33Å
366V98.7Very high98.6Very high5 Ų54.7 Ų4.73%0.032%0.021CC..Hα-helixtrans-61.8-25.7176.769.10000112.2E364 S370 A489 L563 L573 T581E364-V366 PolarHBondContact O-N 3.26Å; V366-S370 VanDerWaalsContact O-CB 3.26Å; V366-S370 WeakPolarHBondContact O-CB 3.32Å; V366-S370 PolarHBondContact O-N 3.2Å; V366-S370 PolarHBondContact O-OG 3.26Å; V366-A489 HydrophobicContact CG1-CB 3.44Å; V366-A489 VanDerWaalsContact CG1-CB 3.44Å; V366-L563 HydrophobicContact CG1-CB 4.26Å; V366-L563 HydrophobicContact CG1-CD1 4.35Å; V366-L573 HydrophobicContact CB-CD2 4.12Å; V366-L573 HydrophobicContact CG2-CD2 3.72Å; V366-T581 HydrophobicContact CG2-CG2 3.84Å
367T98.8Very high98.5Very high0 Ų07.3 Ų7.30%03%0.032CC..Hα-helixtrans-69.2-51.3179.267.40000111T358 G359 E364 W365 A369 S370 G371 I487 A489 L563T358-T367 WeakPolarHBondContact CB-O 3.5Å; T358-T367 VanDerWaalsContact CG2-O 3.22Å; T358-T367 WeakPolarHBondContact CG2-O 3.25Å; G359-T367 WeakPolarHBondContact CA-OG1 3.3Å; G359-T367 PolarHBondContact N-OG1 3.44Å; E364-T367 HydrophobicContact CB-CG2 4.05Å; E364-T367 WeakPolarHBondContact O-CB 3.23Å; E364-T367 VanDerWaalsContact O-CG2 3.31Å; E364-T367 WeakPolarHBondContact O-CG2 3.42Å; E364-T367 PolarHBondContact O-N 3.32Å; E364-T367 PolarHBondContact O-OG1 3.33Å; W365-T367 PolarHBondContact O-N 3.15Å; T367-A369 VanDerWaalsContact C-N 3.34Å; T367-A369 PolarHBondContact O-N 2.92Å; T367-S370 PolarHBondContact O-N 3.33Å; T367-G371 PolarHBondContact O-N 3.3Å; T367-I487 HydrophobicContact CG2-CG2 4.15Å; T367-I487 WeakPolarHBondContact CG2-O 3.11Å; T367-A489 HydrophobicContact CG2-CB 4.08Å; T367-L563 HydrophobicContact CG2-CD1 4.28Å
368Q98.8Very high98.5Very high1 Ų17.3 Ų7.31%0.0053%0.032CC..Hα-helixtrans-63.2-41.8177.8-60.787.8-18.600111I310 E364 W365 S370 G371 L372 I401 Y408I310-Q368 HydrophobicContact CD1-CB 4.24Å; E364-Q368 PolarHBondContact O-OE1 3.14Å; W365-Q368 PolarHBondContact O-N 3.15Å; W365-Q368 PolarHBondContact O-OE1 3.14Å; Q368-S370 VanDerWaalsContact C-N 3.35Å; Q368-S370 PolarHBondContact O-N 2.65Å; Q368-G371 WeakPolarHBondContact O-CA 3.41Å; Q368-G371 PolarHBondContact O-N 2.77Å; Q368-G371 VanDerWaalsContact O-N 3.15Å; Q368-L372 PolarHBondContact O-N 2.82Å; Q368-I401 HydrophobicContact CB-CG2 4.38Å; Q368-I401 WeakPolarHBondContact CG-O 3.22Å; Q368-Y408 HydrophobicContact CB-CE2 4.31Å; Q368-Y408 HydrophobicContact CG-CD2 4.13Å; Q368-Y408 HydrophobicContact CG-CE2 3.91Å
369A98.4Very high98.4Very high5 Ų58.1 Ų8.14%0.0414%0.037CC..Hα-helixtrans-62.1-41.7176.600000112Y304 W365 T367 G371 L372 W373 I578Y304-A369 HydrophobicContact CD1-CB 3.99Å; Y304-A369 HydrophobicContact CE1-CB 4Å; W365-A369 PolarHBondContact O-N 2.96Å; W365-A369 VanDerWaalsContact O-N 3.16Å; T367-A369 VanDerWaalsContact C-N 3.34Å; T367-A369 PolarHBondContact O-N 2.92Å; A369-G371 VanDerWaalsContact C-N 3.34Å; A369-L372 PolarHBondContact O-N 2.89Å; A369-W373 PolarHBondContact O-N 3.36Å; A369-I578 HydrophobicContact CB-CD1 4.08Å; A369-I578 HydrophobicContact CB-CG1 4.17Å; A369-I578 HydrophobicContact CB-CG2 3.64Å
370S98.7Very high98.2Very high0 Ų010.5 Ų10.50%05%0.052CC..Hα-helixtrans-65.2-38.1173.1-57.50000111.6V366 T367 Q368 L372 W373 F374V366-S370 VanDerWaalsContact O-CB 3.26Å; V366-S370 WeakPolarHBondContact O-CB 3.32Å; V366-S370 PolarHBondContact O-N 3.2Å; V366-S370 PolarHBondContact O-OG 3.26Å; T367-S370 PolarHBondContact O-N 3.33Å; Q368-S370 VanDerWaalsContact C-N 3.35Å; Q368-S370 PolarHBondContact O-N 2.65Å; S370-L372 PolarHBondContact O-N 2.88Å; S370-W373 CarbonylContact O-C 3.59Å; S370-W373 WeakPolarHBondContact O-CB 3.39Å; S370-W373 PolarHBondContact O-N 3.1Å; S370-W373 VanDerWaalsContact O-N 3.12Å; S370-F374 WeakPolarHBondContact O-CD2 3.5Å; S370-F374 WeakPolarHBondContact O-CG 3.36Å; S370-F374 PolarHBondContact O-N 3.16Å
371G98.7Very high98.1Very high0 Ų011.6 Ų11.60%06%0.058CC..Hα-helixtrans-56.5-44.2173.900000113.5T367 Q368 A369 W373 F374 A375T367-G371 PolarHBondContact O-N 3.3Å; Q368-G371 WeakPolarHBondContact O-CA 3.41Å; Q368-G371 PolarHBondContact O-N 2.77Å; Q368-G371 VanDerWaalsContact O-N 3.15Å; A369-G371 VanDerWaalsContact C-N 3.34Å; G371-W373 VanDerWaalsContact C-N 3.34Å; G371-W373 PolarHBondContact O-N 3.15Å; G371-F374 PolarHBondContact O-N 2.86Å; G371-A375 PolarHBondContact O-N 2.83Å
372L98.4Very high98.1Very high3 Ų315 Ų152%0.0167%0.071CC..Hα-helixtrans-58.8-46173.1-66.2169.4000111.6F299 Y301 H305 I310 F313 Q368 A369 S370 A375 K376 I401F299-L372 HydrophobicContact CE1-CD1 3.95Å; F299-L372 HydrophobicContact CZ-CD1 4.11Å; Y301-L372 HydrophobicContact CD1-CB 4.33Å; Y301-L372 HydrophobicContact CE1-CB 4.39Å; H305-L372 HydrophobicContact CB-CD1 4.47Å; I310-L372 HydrophobicContact CB-CD2 4.4Å; I310-L372 HydrophobicContact CG1-CD1 4.11Å; I310-L372 HydrophobicContact CG1-CD2 4.2Å; I310-L372 HydrophobicContact CG1-CG 4.48Å; I310-L372 HydrophobicContact CG2-CD2 4.13Å; F313-L372 HydrophobicContact CB-CD2 4.1Å; F313-L372 HydrophobicContact CD1-CD2 3.16Å; F313-L372 HydrophobicContact CD1-CG 4.47Å; F313-L372 HydrophobicContact CE1-CB 4.43Å; F313-L372 HydrophobicContact CE1-CD2 3.71Å; F313-L372 HydrophobicContact CG-CD2 3.72Å; Q368-L372 PolarHBondContact O-N 2.82Å; A369-L372 PolarHBondContact O-N 2.89Å; S370-L372 PolarHBondContact O-N 2.88Å; L372-A375 PolarHBondContact O-N 2.83Å; L372-K376 PolarHBondContact O-N 2.9Å; L372-I401 HydrophobicContact CD2-CD1 4.05Å; L372-I401 HydrophobicContact CD2-CG2 4.34Å; L372-I401 HydrophobicContact CG-CG2 4.29Å
373W98.7Very high98Very high35 Ų3517.8 Ų17.813%0.13310%0.1CC..Hα-helixtrans-65.1-43.6179.6-171.398.8000111.7Y301 A369 S370 G371 A375 K376 K377 A582 E583 W586Y301-W373 HydrophobicContact CD1-CB 4.31Å; A369-W373 PolarHBondContact O-N 3.36Å; S370-W373 CarbonylContact O-C 3.59Å; S370-W373 WeakPolarHBondContact O-CB 3.39Å; S370-W373 PolarHBondContact O-N 3.1Å; S370-W373 VanDerWaalsContact O-N 3.12Å; G371-W373 VanDerWaalsContact C-N 3.34Å; G371-W373 PolarHBondContact O-N 3.15Å; W373-A375 VanDerWaalsContact C-N 3.33Å; W373-A375 PolarHBondContact O-N 3.38Å; W373-K376 PolarHBondContact O-N 2.99Å; W373-K377 HydrophobicContact CE3-CB 3.93Å; W373-K377 HydrophobicContact CE3-CG 4.37Å; W373-K377 HydrophobicContact CH2-CB 4.08Å; W373-K377 HydrophobicContact CH2-CD 3.7Å; W373-K377 HydrophobicContact CH2-CG 3.71Å; W373-K377 HydrophobicContact CZ2-CD 4.24Å; W373-K377 HydrophobicContact CZ3-CB 3.65Å; W373-K377 HydrophobicContact CZ3-CD 4.12Å; W373-K377 HydrophobicContact CZ3-CG 3.59Å; W373-K377 WeakPolarHBondContact O-CB 3.45Å; W373-K377 PolarHBondContact O-N 2.8Å; W373-A582 HydrophobicContact CB-CB 3.9Å; W373-A582 HydrophobicContact CD2-CB 3.69Å; W373-A582 HydrophobicContact CE3-CB 3.75Å; W373-A582 HydrophobicContact CG-CB 3.77Å; W373-E583 HydrophobicContact CH2-CB 4.47Å; W373-E583 HydrophobicContact CH2-CG 3.86Å; W373-E583 HydrophobicContact CZ2-CB 4.49Å; W373-E583 HydrophobicContact CZ2-CG 3.46Å; W373-E583 VanDerWaalsContact CZ2-CG 3.46Å; W373-W586 HydrophobicContact CH2-CB 4.28Å; W373-W586 HydrophobicContact CH2-CG 4.36Å; W373-W586 HydrophobicContact CZ3-CB 3.73Å; W373-W586 HydrophobicContact CZ3-CD2 4.35Å; W373-W586 AromaticContact CZ3-CG 3.88Å; W373-W586 HydrophobicContact CZ3-CG 3.88Å
374F98.8Very high98Very high1 Ų125.3 Ų25.30%0.00413%0.133CC..Hα-helixtrans-58.7-44.6175.8-58.8-35.9000111.5S370 G371 K376 K377 I378 L399 I487 A582 T585 W586 L589S370-F374 WeakPolarHBondContact O-CD2 3.5Å; S370-F374 WeakPolarHBondContact O-CG 3.36Å; S370-F374 PolarHBondContact O-N 3.16Å; G371-F374 PolarHBondContact O-N 2.86Å; F374-K376 VanDerWaalsContact C-N 3.3Å; F374-K376 PolarHBondContact O-N 2.8Å; F374-K377 WeakPolarHBondContact O-CB 3.46Å; F374-K377 PolarHBondContact O-N 3.25Å; F374-K377 VanDerWaalsContact O-N 3.12Å; F374-I378 VanDerWaalsContact O-CG1 3.27Å; F374-I378 WeakPolarHBondContact O-CG1 3.36Å; F374-I378 PolarHBondContact O-N 2.9Å; F374-L399 HydrophobicContact CB-CD2 4.38Å; F374-I487 HydrophobicContact CE2-CD1 3.85Å; F374-A582 HydrophobicContact CE1-CB 4.22Å; F374-A582 WeakPolarHBondContact CE1-O 3.43Å; F374-T585 HydrophobicContact CE1-CG2 4.45Å; F374-T585 HydrophobicContact CZ-CG2 3.75Å; F374-W586 HydrophobicContact CB-CE3 4.43Å; F374-W586 HydrophobicContact CB-CZ3 4.37Å; F374-W586 HydrophobicContact CD1-CB 4.47Å; F374-W586 AromaticContact CD1-CE3 3.72Å; F374-W586 HydrophobicContact CD1-CE3 3.72Å; F374-W586 HydrophobicContact CD1-CZ3 4.46Å; F374-W586 HydrophobicContact CE1-CB 4.27Å; F374-W586 HydrophobicContact CE1-CE3 4.4Å; F374-W586 HydrophobicContact CG-CE3 4.31Å; F374-L589 HydrophobicContact CD1-CD1 4.14Å; F374-L589 HydrophobicContact CD2-CD1 4.06Å; F374-L589 HydrophobicContact CE1-CD1 3.89Å; F374-L589 HydrophobicContact CE2-CD1 3.81Å; F374-L589 HydrophobicContact CG-CD1 4.26Å; F374-L589 HydrophobicContact CZ-CD1 3.73Å
375A98.6Very high97.9Very high0 Ų027.9 Ų27.90%015%0.147CC..Hα-helixtrans-57.6-44.5178.500000111.7F313 L317 L342 F344 G371 L372 W373 L399 I401F313-A375 HydrophobicContact CE1-CB 3.87Å; F313-A375 HydrophobicContact CZ-CB 4.09Å; L317-A375 HydrophobicContact CD2-CB 3.74Å; L342-A375 HydrophobicContact CD1-CB 3.9Å; F344-A375 HydrophobicContact CZ-CB 4.02Å; G371-A375 PolarHBondContact O-N 2.83Å; L372-A375 PolarHBondContact O-N 2.83Å; W373-A375 VanDerWaalsContact C-N 3.33Å; W373-A375 PolarHBondContact O-N 3.38Å; A375-L399 HydrophobicContact CB-CD2 3.77Å; A375-I401 HydrophobicContact CB-CD1 4.33Å
376K98.1Very high97.9Very high29 Ų2932.3 Ų32.313%0.12618%0.179CC..Hα-helixtrans-68.5-38.6175.3-176.558.8174.1-179.80112.3T296 D297 Y301 F313 L372 W373 F374 I378 V379 T380T296-K376 PolarHBondContact OG1-NZ 3.16Å; D297-K376 VanDerWaalsContact OD1-CE 3.3Å; D297-K376 WeakPolarHBondContact OD1-CE 3.34Å; D297-K376 IonicContact OD1-NZ 3.73Å; D297-K376 PolarHBondContact OD1-NZ 3.1Å; Y301-K376 HydrophobicContact CE1-CB 3.82Å; Y301-K376 HydrophobicContact CE1-CG 4.36Å; Y301-K376 HydrophobicContact CE2-CB 4.44Å; Y301-K376 HydrophobicContact CE2-CG 4.08Å; Y301-K376 WeakPolarHBondContact OH-CB 3.47Å; Y301-K376 VanDerWaalsContact OH-CG 3.29Å; Y301-K376 WeakPolarHBondContact OH-CG 3Å; F313-K376 HydrophobicContact CZ-CB 4.49Å; L372-K376 PolarHBondContact O-N 2.9Å; W373-K376 PolarHBondContact O-N 2.99Å; F374-K376 VanDerWaalsContact C-N 3.3Å; F374-K376 PolarHBondContact O-N 2.8Å; K376-I378 PolarHBondContact O-N 3.08Å; K376-V379 HydrophobicContact CD-CG2 4.04Å; K376-V379 WeakPolarHBondContact O-CG2 3.26Å; K376-V379 PolarHBondContact O-N 3.24Å; K376-T380 VanDerWaalsContact O-CB 3.29Å; K376-T380 WeakPolarHBondContact O-CB 3.37Å; K376-T380 PolarHBondContact O-N 2.84Å; K376-T380 PolarHBondContact O-OG1 3.33Å
377K97.4Very high97.8Very high56 Ų5633.5 Ų33.524%0.24319%0.189CC..Hα-helixtrans-61.5-44.2178.7-173.657.6167.7157.30111.4W373 F374 V379 T380 D381 W586W373-K377 HydrophobicContact CE3-CB 3.93Å; W373-K377 HydrophobicContact CE3-CG 4.37Å; W373-K377 HydrophobicContact CH2-CB 4.08Å; W373-K377 HydrophobicContact CH2-CD 3.7Å; W373-K377 HydrophobicContact CH2-CG 3.71Å; W373-K377 HydrophobicContact CZ2-CD 4.24Å; W373-K377 HydrophobicContact CZ3-CB 3.65Å; W373-K377 HydrophobicContact CZ3-CD 4.12Å; W373-K377 HydrophobicContact CZ3-CG 3.59Å; W373-K377 WeakPolarHBondContact O-CB 3.45Å; W373-K377 PolarHBondContact O-N 2.8Å; F374-K377 WeakPolarHBondContact O-CB 3.46Å; F374-K377 PolarHBondContact O-N 3.25Å; F374-K377 VanDerWaalsContact O-N 3.12Å; K377-V379 PolarHBondContact O-N 3Å; K377-T380 PolarHBondContact O-N 3.02Å; K377-D381 WeakPolarHBondContact CD-OD2 3.11Å; K377-D381 WeakPolarHBondContact CE-OD2 3.48Å; K377-D381 IonicContact NZ-OD1 3.02Å; K377-D381 PolarHBondContact NZ-OD1 3.28Å; K377-D381 IonicContact NZ-OD2 2.67Å; K377-D381 PolarHBondContact NZ-OD2 3.24Å; K377-D381 WeakPolarHBondContact O-CB 3.4Å; K377-D381 PolarHBondContact O-N 3.03Å; K377-W586 HydrophobicContact CG-CD2 3.88Å; K377-W586 HydrophobicContact CG-CG 4.16Å; K377-W586 HydrophobicContact CG-CZ2 3.95Å
378I98.3Very high97.8Very high0 Ų033.5 Ų33.50%019%0.189CC..Hα-helixtrans-56.7-51.6178.3-68.6162.8000111.2F344 F374 K376 T380 Y382 L392 I397 W586F344-I378 HydrophobicContact CB-CG2 4.19Å; F344-I378 HydrophobicContact CD1-CB 4.09Å; F344-I378 HydrophobicContact CD1-CG2 3.41Å; F344-I378 VanDerWaalsContact CD1-CG2 3.41Å; F344-I378 HydrophobicContact CD2-CD1 4.03Å; F344-I378 HydrophobicContact CD2-CG2 4.49Å; F344-I378 HydrophobicContact CE1-CB 4.03Å; F344-I378 HydrophobicContact CE1-CD1 4.37Å; F344-I378 HydrophobicContact CE1-CG2 3.88Å; F344-I378 HydrophobicContact CE2-CD1 3.85Å; F344-I378 HydrophobicContact CG-CD1 4.39Å; F344-I378 HydrophobicContact CG-CG2 3.78Å; F344-I378 HydrophobicContact CZ-CB 4.48Å; F344-I378 HydrophobicContact CZ-CD1 4.04Å; F374-I378 VanDerWaalsContact O-CG1 3.27Å; F374-I378 WeakPolarHBondContact O-CG1 3.36Å; F374-I378 PolarHBondContact O-N 2.9Å; K376-I378 PolarHBondContact O-N 3.08Å; I378-T380 VanDerWaalsContact C-N 3.32Å; I378-T380 PolarHBondContact O-N 3.31Å; I378-Y382 WeakPolarHBondContact O-CB 3.07Å; I378-Y382 PolarHBondContact O-N 3Å; I378-L392 HydrophobicContact CG2-CD1 3.77Å; I378-I397 HydrophobicContact CD1-CG2 4.36Å; I378-W586 HydrophobicContact CD1-CH2 4.37Å; I378-W586 HydrophobicContact CD1-CZ3 4.47Å; I378-W586 HydrophobicContact CG1-CH2 3.52Å; I378-W586 HydrophobicContact CG1-CZ2 4.46Å; I378-W586 HydrophobicContact CG1-CZ3 4.01Å
379V97.3Very high97.8Very high17 Ų1734.7 Ų34.710%0.10320%0.196CC..Hα-helixtrans-69.3-31.7-178.8-56.90000112.6L317 N321 L324 V325 F344 K376 K377L317-V379 HydrophobicContact CD1-CG1 4.07Å; L317-V379 HydrophobicContact CD1-CG2 3.75Å; L317-V379 HydrophobicContact CG-CG1 4.41Å; N321-V379 HydrophobicContact CB-CG1 4.32Å; L324-V379 HydrophobicContact CD2-CG1 4.28Å; V325-V379 HydrophobicContact CG2-CG1 3.5Å; F344-V379 HydrophobicContact CD1-CG1 4.23Å; F344-V379 HydrophobicContact CE1-CG1 3.86Å; K376-V379 HydrophobicContact CD-CG2 4.04Å; K376-V379 WeakPolarHBondContact O-CG2 3.26Å; K376-V379 PolarHBondContact O-N 3.24Å; K377-V379 PolarHBondContact O-N 3Å
380T95.4Very high97.8Very high51 Ų5135.8 Ų35.831%0.31321%0.205SC..Hα-helixtrans-74-35.2-176.9-59.60000111.8K376 K377 I378 K384K376-T380 VanDerWaalsContact O-CB 3.29Å; K376-T380 WeakPolarHBondContact O-CB 3.37Å; K376-T380 PolarHBondContact O-N 2.84Å; K376-T380 PolarHBondContact O-OG1 3.33Å; K377-T380 PolarHBondContact O-N 3.02Å; I378-T380 VanDerWaalsContact C-N 3.32Å; I378-T380 PolarHBondContact O-N 3.31Å; T380-K384 WeakPolarHBondContact O-CD 3.38Å; T380-K384 WeakPolarHBondContact O-CE 3.44Å; T380-K384 PolarHBondContact O-NZ 2.96Å
381D96.8Very high97.8Very high24 Ų2435.8 Ų35.813%0.12821%0.205CC..Hα-helixtrans-94.3-20.4-175.6-7714.1000113.3K377 G383 K384 D385 L388K377-D381 WeakPolarHBondContact CD-OD2 3.11Å; K377-D381 WeakPolarHBondContact CE-OD2 3.48Å; K377-D381 IonicContact NZ-OD1 3.02Å; K377-D381 PolarHBondContact NZ-OD1 3.28Å; K377-D381 IonicContact NZ-OD2 2.67Å; K377-D381 PolarHBondContact NZ-OD2 3.24Å; K377-D381 WeakPolarHBondContact O-CB 3.4Å; K377-D381 PolarHBondContact O-N 3.03Å; D381-G383 PolarHBondContact O-N 3.02Å; D381-K384 WeakPolarHBondContact O-CA 3.35Å; D381-K384 PolarHBondContact O-N 3.22Å; D381-D385 HydrophobicContact CB-CB 4.11Å; D381-D385 PolarHBondContact O-N 3.47Å; D381-L388 HydrophobicContact CB-CD2 3.52Å
382Y97.5Very high97.7Very high73 Ų7335.8 Ų35.829%0.28621%0.205SC..THydrogen-bonded Turntrans-59.5126.6174.7177.9-105.8000111L324 T346 I378 K384 T389 L392 N393L324-Y382 HydrophobicContact CD1-CD1 4.12Å; L324-Y382 HydrophobicContact CD1-CE1 4.16Å; L324-Y382 HydrophobicContact CD1-CG 4.37Å; L324-Y382 HydrophobicContact CD2-CD1 3.66Å; L324-Y382 HydrophobicContact CD2-CE1 4.41Å; L324-Y382 HydrophobicContact CD2-CG 3.93Å; T346-Y382 HydrophobicContact CG2-CE1 4.34Å; T346-Y382 HydrophobicContact CG2-CE2 3.78Å; T346-Y382 VanDerWaalsContact CG2-CZ 3.49Å; T346-Y382 WeakPolarHBondContact CG2-OH 3.49Å; I378-Y382 WeakPolarHBondContact O-CB 3.07Å; I378-Y382 PolarHBondContact O-N 3Å; Y382-K384 VanDerWaalsContact C-N 3.3Å; Y382-T389 HydrophobicContact CD2-CG2 4.38Å; Y382-T389 HydrophobicContact CE2-CG2 4.06Å; Y382-L392 HydrophobicContact CD2-CB 3.75Å; Y382-L392 HydrophobicContact CD2-CD1 3.51Å; Y382-L392 HydrophobicContact CD2-CG 4.3Å; Y382-L392 HydrophobicContact CE2-CB 3.78Å; Y382-L392 HydrophobicContact CE2-CD1 4.32Å; Y382-L392 HydrophobicContact CG-CD1 3.97Å; Y382-N393 PolarHBondContact OH-OD1 3.45Å; Y382-N393 VanDerWaalsContact OH-OD1 3.12Å
383G96.1Very high97.7Very high60 Ų6039.2 Ų39.262%0.61922%0.224SC*.THydrogen-bonded Turntrans83.5-4.3-17200000115D381 T389D381-G383 PolarHBondContact O-N 3.02Å; G383-T389 WeakPolarHBondContact CA-OG1 3.39Å; G383-T389 PolarHBondContact N-OG1 3.08Å
384K96.6Very high97.6Very high162 Ų16241.5 Ų41.570%0.70424%0.239SC*.THydrogen-bonded Turntrans-116.5-50.3176.7-59.5-179.4-168149.10112.3T380 D381 Y382T380-K384 WeakPolarHBondContact O-CD 3.38Å; T380-K384 WeakPolarHBondContact O-CE 3.44Å; T380-K384 PolarHBondContact O-NZ 2.96Å; D381-K384 WeakPolarHBondContact O-CA 3.35Å; D381-K384 PolarHBondContact O-N 3.22Å; Y382-K384 VanDerWaalsContact C-N 3.3Å
385D97.2Very high97.6Very high56 Ų5641.7 Ų41.730%0.29924%0.24SC..SBendtrans-83.2120.5173.5-178.5-88.1000109.8D381 A387 L388 T389D381-D385 HydrophobicContact CB-CB 4.11Å; D381-D385 PolarHBondContact O-N 3.47Å; D385-A387 VanDerWaalsContact C-N 3.34Å; D385-A387 PolarHBondContact O-N 2.87Å; D385-A387 WeakPolarHBondContact OD1-CA 3.49Å; D385-A387 WeakPolarHBondContact OD1-CB 3.44Å; D385-A387 PolarHBondContact OD1-N 3.09Å; D385-L388 HydrophobicContact CB-CB 4.15Å; D385-L388 WeakPolarHBondContact OD1-CB 3.48Å; D385-L388 PolarHBondContact OD1-N 2.95Å; D385-T389 WeakPolarHBondContact O-CB 3.37Å; D385-T389 PolarHBondContact O-N 3.21Å; D385-T389 PolarHBondContact O-OG1 3.48Å
386S98.1Very high97.6Very high100 Ų10041.7 Ų41.770%0.69924%0.24SC*.Hα-helixtrans-67.4-33-174.154.20000113.3A390S386-A390 WeakPolarHBondContact O-CB 3.5Å; S386-A390 PolarHBondContact O-N 2.84Å
387A97.6Very high97.7Very high31 Ų3140.3 Ų40.326%0.25623%0.234SC..Hα-helixtrans-74.1-49.6-17800000110.5D385 T389 A390 I391 M590D385-A387 VanDerWaalsContact C-N 3.34Å; D385-A387 PolarHBondContact O-N 2.87Å; D385-A387 WeakPolarHBondContact OD1-CA 3.49Å; D385-A387 WeakPolarHBondContact OD1-CB 3.44Å; D385-A387 PolarHBondContact OD1-N 3.09Å; A387-T389 VanDerWaalsContact C-N 3.29Å; A387-T389 PolarHBondContact O-N 3.13Å; A387-A390 WeakPolarHBondContact O-CB 3.22Å; A387-A390 PolarHBondContact O-N 3.49Å; A387-A390 VanDerWaalsContact O-N 3.15Å; A387-I391 WeakPolarHBondContact O-CD1 3.38Å; A387-I391 VanDerWaalsContact O-CG1 3.3Å; A387-I391 WeakPolarHBondContact O-CG1 3.32Å; A387-I391 PolarHBondContact O-N 3.24Å; A387-M590 HydrophobicContact CB-CE 3.93Å
388L98.3Very high97.7Very high0 Ų037.8 Ų37.80%022%0.223CC..Hα-helixtrans-59.9-41.6175.1-179.966.9000111.3D381 D385 A390 I391 L392 I397 W586 M590D381-L388 HydrophobicContact CB-CD2 3.52Å; D385-L388 HydrophobicContact CB-CB 4.15Å; D385-L388 WeakPolarHBondContact OD1-CB 3.48Å; D385-L388 PolarHBondContact OD1-N 2.95Å; L388-A390 VanDerWaalsContact C-N 3.34Å; L388-A390 PolarHBondContact O-N 2.84Å; L388-I391 PolarHBondContact O-N 2.64Å; L388-L392 HydrophobicContact CD1-CD1 4.26Å; L388-L392 HydrophobicContact CD1-CG 4.41Å; L388-L392 HydrophobicContact CG-CD1 4.23Å; L388-L392 PolarHBondContact O-N 2.91Å; L388-I397 HydrophobicContact CD1-CD1 4.37Å; L388-W586 HydrophobicContact CD1-CH2 4.28Å; L388-W586 HydrophobicContact CD1-CZ2 4.26Å; L388-W586 HydrophobicContact CD2-CZ2 4.27Å; L388-M590 HydrophobicContact CB-CE 3.94Å; L388-M590 HydrophobicContact CB-SD 4.28Å; L388-M590 HydrophobicContact CD1-SD 4.17Å
389T98.4Very high97.8Very high25 Ų2537.8 Ų37.815%0.15322%0.223CC..Hα-helixtrans-62.3-42.5176.6-57.70000111.1Y382 G383 D385 A387 L392 N393Y382-T389 HydrophobicContact CD2-CG2 4.38Å; Y382-T389 HydrophobicContact CE2-CG2 4.06Å; G383-T389 WeakPolarHBondContact CA-OG1 3.39Å; G383-T389 PolarHBondContact N-OG1 3.08Å; D385-T389 WeakPolarHBondContact O-CB 3.37Å; D385-T389 PolarHBondContact O-N 3.21Å; D385-T389 PolarHBondContact O-OG1 3.48Å; A387-T389 VanDerWaalsContact C-N 3.29Å; A387-T389 PolarHBondContact O-N 3.13Å; T389-L392 PolarHBondContact O-N 3.08Å; T389-N393 VanDerWaalsContact O-CB 3.25Å; T389-N393 WeakPolarHBondContact O-CB 3.34Å; T389-N393 PolarHBondContact O-N 2.9Å; T389-N393 PolarHBondContact O-ND2 3.17Å
390A98.2Very high97.8Very high28 Ų2837 Ų3723%0.23122%0.218CC..Hα-helixtrans-64-41.3175.300000112.3S386 A387 L388 N393 N394 Y597S386-A390 WeakPolarHBondContact O-CB 3.5Å; S386-A390 PolarHBondContact O-N 2.84Å; A387-A390 WeakPolarHBondContact O-CB 3.22Å; A387-A390 PolarHBondContact O-N 3.49Å; A387-A390 VanDerWaalsContact O-N 3.15Å; L388-A390 VanDerWaalsContact C-N 3.34Å; L388-A390 PolarHBondContact O-N 2.84Å; A390-N393 PolarHBondContact O-N 3.08Å; A390-N394 PolarHBondContact O-N 2.98Å; A390-N394 PolarHBondContact O-ND2 2.9Å; A390-Y597 HydrophobicContact CB-CE1 3.98Å
391I98.4Very high98Very high0 Ų034.6 Ų34.60%020%0.203CC..Hα-helixtrans-58.9-57.3174.3-67.4157.6000109.6I354 A387 L388 N393 N394 M395 I397 M590 M593 D594 Y597I354-I391 HydrophobicContact CD1-CG2 3.98Å; A387-I391 WeakPolarHBondContact O-CD1 3.38Å; A387-I391 VanDerWaalsContact O-CG1 3.3Å; A387-I391 WeakPolarHBondContact O-CG1 3.32Å; A387-I391 PolarHBondContact O-N 3.24Å; L388-I391 PolarHBondContact O-N 2.64Å; I391-N393 PolarHBondContact O-N 3.4Å; I391-N394 PolarHBondContact O-N 3.45Å; I391-M395 HydrophobicContact CG2-CB 4.4Å; I391-M395 WeakPolarHBondContact O-CA 3.5Å; I391-M395 WeakPolarHBondContact O-CB 3.4Å; I391-M395 PolarHBondContact O-N 2.69Å; I391-I397 HydrophobicContact CG2-CD1 4.42Å; I391-M590 HydrophobicContact CD1-CE 4.09Å; I391-M593 HydrophobicContact CD1-CB 3.84Å; I391-D594 HydrophobicContact CD1-CB 4.34Å; I391-Y597 HydrophobicContact CG1-CD1 4.36Å; I391-Y597 HydrophobicContact CG1-CG 4.17Å
392L98.3Very high98.1Very high0 Ų033.7 Ų33.70%020%0.199CC..Hα-helixtrans-68.2-17.8-177.6-79.6174.7000114.5L324 F344 T346 R351 I378 Y382 L388 T389 I397L324-L392 HydrophobicContact CD1-CD1 4.39Å; F344-L392 HydrophobicContact CB-CD2 3.78Å; T346-L392 HydrophobicContact CG2-CB 4.45Å; T346-L392 VanDerWaalsContact CG2-O 3.24Å; T346-L392 WeakPolarHBondContact CG2-O 3.34Å; T346-L392 PolarHBondContact OG1-O 3.47Å; R351-L392 PolarHBondContact NH2-O 2.96Å; I378-L392 HydrophobicContact CG2-CD1 3.77Å; Y382-L392 HydrophobicContact CD2-CB 3.75Å; Y382-L392 HydrophobicContact CD2-CD1 3.51Å; Y382-L392 HydrophobicContact CD2-CG 4.3Å; Y382-L392 HydrophobicContact CE2-CB 3.78Å; Y382-L392 HydrophobicContact CE2-CD1 4.32Å; Y382-L392 HydrophobicContact CG-CD1 3.97Å; L388-L392 HydrophobicContact CD1-CD1 4.26Å; L388-L392 HydrophobicContact CD1-CG 4.41Å; L388-L392 HydrophobicContact CG-CD1 4.23Å; L388-L392 PolarHBondContact O-N 2.91Å; T389-L392 PolarHBondContact O-N 3.08Å; L392-I397 HydrophobicContact CD2-CD1 3.89Å; L392-I397 HydrophobicContact CD2-CG1 4.01Å; L392-I397 HydrophobicContact CG-CD1 4.29Å
393N97.6Very high98.1Very high76 Ų7630.3 Ų30.341%0.40619%0.186SC..Hα-helixtrans-78.9-19.9171.6-76.3-14.7000113.2R351 Y382 T389 A390 I391R351-N393 PolarHBondContact NH2-O 2.83Å; Y382-N393 PolarHBondContact OH-OD1 3.45Å; Y382-N393 VanDerWaalsContact OH-OD1 3.12Å; T389-N393 VanDerWaalsContact O-CB 3.25Å; T389-N393 WeakPolarHBondContact O-CB 3.34Å; T389-N393 PolarHBondContact O-N 2.9Å; T389-N393 PolarHBondContact O-ND2 3.17Å; A390-N393 PolarHBondContact O-N 3.08Å; I391-N393 PolarHBondContact O-N 3.4Å
394N97.3Very high98.3Very high82 Ų8227.5 Ų27.544%0.43916%0.157SC..Hα-helixtrans-118.4-24.3-178-66.3-82.6000114.2R351 A390 I391 Y597R351-N394 PolarHBondContact NE-O 3.3Å; A390-N394 PolarHBondContact O-N 2.98Å; A390-N394 PolarHBondContact O-ND2 2.9Å; I391-N394 PolarHBondContact O-N 3.45Å; N394-Y597 HydrophobicContact CB-CD2 3.99Å; N394-Y597 HydrophobicContact CB-CE2 3.65Å; N394-Y597 WeakPolarHBondContact ND2-CE2 3.28Å
395M98.4Very high98.4Very high5 Ų519.8 Ų19.83%0.02512%0.123CC..  trans-125.3157.4-178.4-56-170.674.600112.6R351 P352 I354 I391 K482 T596R351-M395 PolarHBondContact NH2-O 2.96Å; P352-M395 HydrophobicContact CB-CE 3.88Å; P352-M395 HydrophobicContact CB-CG 4.33Å; P352-M395 CarbonylContact O-C 3.49Å; P352-M395 WeakPolarHBondContact O-CA 3.33Å; P352-M395 VanDerWaalsContact O-CB 3.26Å; P352-M395 WeakPolarHBondContact O-CB 3.33Å; I354-M395 HydrophobicContact CD1-CE 4.05Å; I354-M395 HydrophobicContact CD1-SD 3.95Å; I354-M395 HydrophobicContact CG1-CE 3.85Å; I354-M395 HydrophobicContact CG1-SD 4.41Å; I391-M395 HydrophobicContact CG2-CB 4.4Å; I391-M395 WeakPolarHBondContact O-CA 3.5Å; I391-M395 WeakPolarHBondContact O-CB 3.4Å; I391-M395 PolarHBondContact O-N 2.69Å; M395-K482 HydrophobicContact CE-CB 4Å; M395-K482 HydrophobicContact CE-CG 4.09Å; M395-T596 HydrophobicContact CE-CG2 3.68Å; M395-T596 HydrophobicContact SD-CG2 4.23Å
396D98.8Very high98.3Very high0 Ų017.1 Ų17.10%011%0.109CC..EExtended strand (participates in β ladder)trans-95.3148.6167.2-70.9-10000109.6K343 F344 S345 R351 P352 A353 I354 F398K343-D396 WeakPolarHBondContact CE-OD2 3.25Å; K343-D396 IonicContact NZ-OD2 2.95Å; K343-D396 PolarHBondContact NZ-OD2 3.47Å; F344-D396 WeakPolarHBondContact O-CA 3.3Å; S345-D396 WeakPolarHBondContact CB-OD1 3.46Å; S345-D396 PolarHBondContact OG-OD1 2.79Å; R351-D396 IonicContact CZ-OD1 3.82Å; R351-D396 IonicContact NE-OD1 2.84Å; P352-D396 PolarHBondContact O-N 2.89Å; A353-D396 CarbonylContact C-O 3.43Å; A353-D396 WeakPolarHBondContact CA-O 3.27Å; A353-D396 HydrophobicContact CB-CB 4.16Å; I354-D396 PolarHBondContact N-O 3.03Å; D396-F398 HydrophobicContact CB-CE2 4.13Å; D396-F398 HydrophobicContact CB-CZ 4.47Å
397I98.9Very high98Very high0 Ų012.3 Ų12.30%08%0.076CC..EExtended strand (participates in β ladder)trans-114.6128.2168.8-58173.3000108.4K343 F344 I354 I356 I378 L388 I391 L392 M593K343-I397 WeakPolarHBondContact CA-O 3.46Å; F344-I397 HydrophobicContact CB-CB 4.24Å; F344-I397 HydrophobicContact CD2-CB 4.25Å; F344-I397 HydrophobicContact CD2-CG2 4.29Å; F344-I397 PolarHBondContact N-O 2.78Å; F344-I397 PolarHBondContact O-N 3.29Å; I354-I397 HydrophobicContact CB-CG1 4.46Å; I354-I397 HydrophobicContact CD1-CG1 4.49Å; I354-I397 CarbonylContact O-C 3.6Å; I354-I397 WeakPolarHBondContact O-CA 3.36Å; I356-I397 HydrophobicContact CD1-CG2 4.24Å; I378-I397 HydrophobicContact CD1-CG2 4.36Å; L388-I397 HydrophobicContact CD1-CD1 4.37Å; I391-I397 HydrophobicContact CG2-CD1 4.42Å; L392-I397 HydrophobicContact CD2-CD1 3.89Å; L392-I397 HydrophobicContact CD2-CG1 4.01Å; L392-I397 HydrophobicContact CG-CD1 4.29Å; I397-M593 HydrophobicContact CD1-SD 3.8Å; I397-M593 HydrophobicContact CG1-SD 4.5Å
398F98.9Very high98Very high3 Ų311 Ų111%0.0136%0.064CC..EExtended strand (participates in β ladder)trans-107.7126.6170.7-65.3-79.3000109I328 V341 L342 K343 A353 I354 W355 I356 D396 F474 H478I328-F398 HydrophobicContact CD1-CD1 4.43Å; I328-F398 HydrophobicContact CD1-CE1 3.85Å; V341-F398 HydrophobicContact CG1-CB 3.86Å; V341-F398 HydrophobicContact CG1-CD1 3.98Å; V341-F398 HydrophobicContact CG1-CG 4.41Å; L342-F398 CarbonylContact O-C 3.6Å; L342-F398 WeakPolarHBondContact O-CA 3.42Å; K343-F398 HydrophobicContact CB-CD1 3.9Å; K343-F398 HydrophobicContact CB-CE1 3.73Å; K343-F398 HydrophobicContact CD-CE1 3.67Å; K343-F398 HydrophobicContact CD-CZ 4.01Å; K343-F398 HydrophobicContact CG-CD1 4.11Å; K343-F398 HydrophobicContact CG-CE1 3.59Å; K343-F398 HydrophobicContact CG-CZ 4.15Å; A353-F398 HydrophobicContact CB-CD2 3.84Å; A353-F398 HydrophobicContact CB-CE2 3.59Å; I354-F398 PolarHBondContact O-N 2.76Å; W355-F398 HydrophobicContact CD2-CB 4.49Å; W355-F398 HydrophobicContact CE3-CB 3.74Å; W355-F398 HydrophobicContact CE3-CG 4.43Å; W355-F398 HydrophobicContact CZ3-CB 4.19Å; I356-F398 PolarHBondContact N-O 3.49Å; D396-F398 HydrophobicContact CB-CE2 4.13Å; D396-F398 HydrophobicContact CB-CZ 4.47Å; F398-F474 HydrophobicContact CD1-CE1 4.3Å; F398-F474 AromaticContact CD1-CZ 3.73Å; F398-F474 HydrophobicContact CD1-CZ 3.73Å; F398-F474 HydrophobicContact CD2-CE1 4.22Å; F398-F474 HydrophobicContact CD2-CZ 4.24Å; F398-F474 HydrophobicContact CE1-CE1 4.44Å; F398-F474 HydrophobicContact CE1-CE2 4.38Å; F398-F474 AromaticContact CE1-CZ 3.56Å; F398-F474 HydrophobicContact CE1-CZ 3.56Å; F398-F474 HydrophobicContact CE2-CE1 4.36Å; F398-F474 HydrophobicContact CE2-CZ 4.1Å; F398-F474 HydrophobicContact CG-CE1 4.19Å; F398-F474 HydrophobicContact CG-CZ 4.07Å; F398-F474 HydrophobicContact CZ-CE1 4.47Å; F398-F474 AromaticContact CZ-CZ 3.77Å; F398-F474 HydrophobicContact CZ-CZ 3.77Å; F398-H478 AromaticContact CE2-CD2 3.85Å; F398-H478 AromaticContact CE2-NE2 3.56Å; F398-H478 AromaticContact CZ-CD2 3.92Å; F398-H478 AromaticContact CZ-NE2 3.83Å
399L98.9Very high97.6Very high1 Ų113.7 Ų13.71%0.0058%0.075CC..EExtended strand (participates in β ladder)trans-125.3113.7179.917861.7000110.6L342 F344 I356 F374 A375 I401L342-L399 HydrophobicContact CB-CB 4.48Å; L342-L399 PolarHBondContact N-O 2.48Å; L342-L399 PolarHBondContact O-N 2.98Å; F344-L399 HydrophobicContact CE2-CB 3.94Å; F344-L399 HydrophobicContact CE2-CD2 4.24Å; I356-L399 HydrophobicContact CB-CD1 3.85Å; I356-L399 HydrophobicContact CG2-CD1 3.75Å; I356-L399 CarbonylContact O-C 3.58Å; I356-L399 VanDerWaalsContact O-CA 3.28Å; I356-L399 WeakPolarHBondContact O-CA 3.41Å; F374-L399 HydrophobicContact CB-CD2 4.38Å; A375-L399 HydrophobicContact CB-CD2 3.77Å; L399-I401 HydrophobicContact CD2-CG1 4.22Å; L399-I401 HydrophobicContact CG-CG1 4.01Å
400E98.9Very high97.1Very high0 Ų014.4 Ų14.40%08%0.075CC..EExtended strand (participates in β ladder)trans-100.6105.4172.6-167.7177.1-146.500110V341 W355 I356 D357 T358 T403 I471V341-E400 HydrophobicContact CG2-CB 4.14Å; V341-E400 HydrophobicContact CG2-CG 4.16Å; W355-E400 HydrophobicContact CH2-CB 4.34Å; W355-E400 HydrophobicContact CZ2-CB 3.96Å; W355-E400 WeakPolarHBondContact CZ2-OE2 3.37Å; I356-E400 PolarHBondContact O-N 2.81Å; D357-E400 WeakPolarHBondContact CA-O 3.3Å; D357-E400 HydrophobicContact CB-CB 4.21Å; T358-E400 PolarHBondContact N-O 3.34Å; T358-E400 PolarHBondContact OG1-O 2.78Å; E400-T403 VanDerWaalsContact CD-OG1 3.3Å; E400-T403 WeakPolarHBondContact CG-OG1 3.45Å; E400-T403 PolarHBondContact OE2-OG1 2.98Å; E400-I471 WeakPolarHBondContact OE2-CD1 3.36Å
401I98.8Very high96.4Very high0 Ų013.2 Ų13.20%07%0.066CC..SBendtrans-77.6-34-171.9-61.2178.6000112.2I310 F313 Q314 L342 T358 Q368 L372 A375 L399I310-I401 HydrophobicContact CG2-CB 4.3Å; I310-I401 HydrophobicContact CG2-CG2 3.82Å; F313-I401 HydrophobicContact CE1-CD1 4.35Å; Q314-I401 HydrophobicContact CG-CD1 4.38Å; L342-I401 HydrophobicContact CD1-CD1 4.04Å; T358-I401 CarbonylContact O-C 3.09Å; T358-I401 VanDerWaalsContact O-O 3.12Å; T358-I401 VanDerWaalsContact OG1-C 3.25Å; T358-I401 VanDerWaalsContact OG1-CA 3.26Å; T358-I401 WeakPolarHBondContact OG1-CA 3.35Å; T358-I401 PolarHBondContact OG1-O 3.42Å; Q368-I401 HydrophobicContact CB-CG2 4.38Å; Q368-I401 WeakPolarHBondContact CG-O 3.22Å; L372-I401 HydrophobicContact CD2-CD1 4.05Å; L372-I401 HydrophobicContact CD2-CG2 4.34Å; L372-I401 HydrophobicContact CG-CG2 4.29Å; A375-I401 HydrophobicContact CB-CD1 4.33Å; L399-I401 HydrophobicContact CD2-CG1 4.22Å; L399-I401 HydrophobicContact CG-CG1 4.01Å
402A98.3Very high95.7Very high5 Ų515.2 Ų15.24%0.0418%0.075CC..  trans-130.678.8-176.700000109.8L307 N404 P405L307-A402 HydrophobicContact CD1-CB 3.84Å; A402-N404 VanDerWaalsContact C-N 3.32Å; A402-N404 PolarHBondContact O-N 3.04Å; A402-P405 WeakPolarHBondContact O-CD 3.39Å
403T98.9Very high94.6Very high2 Ų216.4 Ų16.41%0.0128%0.082CC..SBendtrans-68.1-28.5-176.8-64.20000113.6D357 T358 I360 E400 P405 I471D357-T403 WeakPolarHBondContact CB-OG1 3.37Å; T358-T403 PolarHBondContact O-N 3.2Å; T358-T403 PolarHBondContact O-OG1 2.89Å; I360-T403 HydrophobicContact CB-CG2 3.88Å; I360-T403 HydrophobicContact CD1-CG2 4.21Å; I360-T403 HydrophobicContact CG1-CG2 3.8Å; E400-T403 VanDerWaalsContact CD-OG1 3.3Å; E400-T403 WeakPolarHBondContact CG-OG1 3.45Å; E400-T403 PolarHBondContact OE2-OG1 2.98Å; T403-P405 VanDerWaalsContact C-CD 3.5Å; T403-P405 WeakPolarHBondContact O-CD 3.39Å; T403-I471 HydrophobicContact CG2-CD1 3.67Å
404N98.8Very high93.6Very high1 Ų113.4 Ų13.41%0.0057%0.067CC..SBendtrans-11874.9172.7178.97.8000110.4G359 I360 A402 D406 G407 Y408 R419 K420G359-N404 WeakPolarHBondContact O-CB 3.31Å; G359-N404 PolarHBondContact O-N 2.89Å; I360-N404 WeakPolarHBondContact O-CB 3.28Å; I360-N404 PolarHBondContact O-ND2 2.99Å; A402-N404 VanDerWaalsContact C-N 3.32Å; A402-N404 PolarHBondContact O-N 3.04Å; N404-D406 VanDerWaalsContact C-N 3.33Å; N404-D406 PolarHBondContact O-N 3.22Å; N404-G407 PolarHBondContact O-N 3.19Å; N404-G407 PolarHBondContact OD1-N 2.94Å; N404-Y408 WeakPolarHBondContact O-CB 3.32Å; N404-Y408 PolarHBondContact O-N 2.95Å; N404-R419 PolarHBondContact ND2-O 3.13Å; N404-K420 VanDerWaalsContact ND2-C 3.35Å; N404-K420 PolarHBondContact ND2-O 2.86Å
405P98.6Very high92.8Very high0 Ų010.1 Ų10.10%05%0.049CC..Hα-helixtrans-68.8-30.1-172.128.9-36.2000112.9L307 R337 L339 A402 T403 Y408 Y409L307-P405 HydrophobicContact CD1-CB 4.03Å; L307-P405 HydrophobicContact CD2-CB 3.81Å; R337-P405 HydrophobicContact CB-CB 4.33Å; R337-P405 HydrophobicContact CB-CG 4.22Å; L339-P405 HydrophobicContact CD2-CG 3.77Å; A402-P405 WeakPolarHBondContact O-CD 3.39Å; T403-P405 VanDerWaalsContact C-CD 3.5Å; T403-P405 WeakPolarHBondContact O-CD 3.39Å; P405-Y408 PolarHBondContact O-N 3.23Å; P405-Y409 VanDerWaalsContact O-CB 3.32Å; P405-Y409 WeakPolarHBondContact O-CB 3.34Å; P405-Y409 PolarHBondContact O-N 2.81Å
406D95.7Very high92.4Very high0 Ų010 Ų100%05%0.049CC..Hα-helixtrans-69.8-47.7178.4-63.7-7.6000111S333 Y334 E335 R337 N404 Y408 Y409 F410 R422S333-D406 VanDerWaalsContact CB-CG 3.44Å; S333-D406 VanDerWaalsContact CB-OD1 3.23Å; S333-D406 WeakPolarHBondContact CB-OD1 3.39Å; S333-D406 VanDerWaalsContact CB-OD2 3.26Å; S333-D406 WeakPolarHBondContact CB-OD2 3.08Å; S333-D406 PolarHBondContact OG-OD1 3.2Å; S333-D406 PolarHBondContact OG-OD2 3.3Å; S333-D406 VanDerWaalsContact OG-OD2 3.11Å; Y334-D406 PolarHBondContact N-OD2 3.13Å; E335-D406 WeakPolarHBondContact CB-OD2 3.41Å; E335-D406 HydrophobicContact CG-CB 4.37Å; E335-D406 WeakPolarHBondContact CG-OD2 3.28Å; E335-D406 PolarHBondContact N-OD2 3.33Å; R337-D406 IonicContact CZ-OD1 3.39Å; R337-D406 VanDerWaalsContact NH1-CG 3.35Å; R337-D406 IonicContact NH1-OD1 3.6Å; R337-D406 PolarHBondContact NH1-OD1 3.19Å; N404-D406 VanDerWaalsContact C-N 3.33Å; N404-D406 PolarHBondContact O-N 3.22Å; D406-Y408 VanDerWaalsContact C-N 3.33Å; D406-Y408 PolarHBondContact O-N 2.88Å; D406-Y409 PolarHBondContact O-N 3.06Å; D406-F410 WeakPolarHBondContact O-CB 3.42Å; D406-F410 PolarHBondContact O-N 2.86Å; D406-R422 HydrophobicContact CB-CB 3.84Å; D406-R422 HydrophobicContact CB-CG 3.77Å
407G91.6Very high92Very high0 Ų010.3 Ų10.30%05%0.05CC..Hα-helixtrans-59.9-45.3172.400000111.1S362 N404 Y409 F410 T411S362-G407 WeakPolarHBondContact CB-O 3.42Å; N404-G407 PolarHBondContact O-N 3.19Å; N404-G407 PolarHBondContact OD1-N 2.94Å; G407-Y409 PolarHBondContact O-N 2.66Å; G407-F410 CarbonylContact O-C 3.57Å; G407-F410 WeakPolarHBondContact O-CA 3.14Å; G407-F410 WeakPolarHBondContact O-CB 3.5Å; G407-F410 PolarHBondContact O-N 3.41Å; G407-F410 VanDerWaalsContact O-N 3.09Å; G407-T411 WeakPolarHBondContact O-CG2 3.46Å; G407-T411 PolarHBondContact O-N 3.12Å
408Y97.9Very high91.7Very high3 Ų311.8 Ų11.81%0.0126%0.056CC..Hα-helixtrans-61.7-46-178.8-171.7-108.5000111.2H305 L307 I310 W365 Q368 N404 P405 D406 F410 T411 H412H305-Y408 WeakPolarHBondContact O-CE1 3.46Å; H305-Y408 PolarHBondContact O-OH 3.48Å; L307-Y408 HydrophobicContact CB-CD1 4.11Å; L307-Y408 HydrophobicContact CD1-CD1 4.17Å; I310-Y408 HydrophobicContact CD1-CD1 4.32Å; I310-Y408 HydrophobicContact CD1-CE1 3.53Å; W365-Y408 AromaticContact CD1-CD2 3.95Å; W365-Y408 AromaticContact CD1-CE2 3.45Å; W365-Y408 VanDerWaalsContact CD1-CE2 3.45Å; W365-Y408 HydrophobicContact CG-CE2 4.06Å; W365-Y408 AromaticContact NE1-CD2 3.9Å; W365-Y408 AromaticContact NE1-CE2 3.57Å; Q368-Y408 HydrophobicContact CB-CE2 4.31Å; Q368-Y408 HydrophobicContact CG-CD2 4.13Å; Q368-Y408 HydrophobicContact CG-CE2 3.91Å; N404-Y408 WeakPolarHBondContact O-CB 3.32Å; N404-Y408 PolarHBondContact O-N 2.95Å; P405-Y408 PolarHBondContact O-N 3.23Å; D406-Y408 VanDerWaalsContact C-N 3.33Å; D406-Y408 PolarHBondContact O-N 2.88Å; Y408-F410 VanDerWaalsContact C-N 3.29Å; Y408-F410 PolarHBondContact O-N 2.91Å; Y408-T411 PolarHBondContact O-N 3.48Å; Y408-T411 VanDerWaalsContact O-N 3.13Å; Y408-T411 PolarHBondContact O-OG1 3.35Å; Y408-H412 AromaticContact CE1-CD2 3.91Å; Y408-H412 AromaticContact CE1-NE2 3.52Å; Y408-H412 AromaticContact CE2-NE2 3.78Å; Y408-H412 AromaticContact CZ-CD2 3.93Å; Y408-H412 AromaticContact CZ-NE2 3.23Å; Y408-H412 PolarHBondContact O-CD2 3.26Å; Y408-H412 PolarHBondContact O-N 3.29Å; Y408-H412 PolarHBondContact OH-NE2 3.11Å
409Y90Very high91.6Very high57 Ų5712.7 Ų12.722%0.2246%0.059CC..Hα-helixtrans-55.9-45.4172.5-176.9-89.5000111.7R337 P405 D406 G407 T411 H412 T413R337-Y409 VanDerWaalsContact NH2-CG 3.32Å; P405-Y409 VanDerWaalsContact O-CB 3.32Å; P405-Y409 WeakPolarHBondContact O-CB 3.34Å; P405-Y409 PolarHBondContact O-N 2.81Å; D406-Y409 PolarHBondContact O-N 3.06Å; G407-Y409 PolarHBondContact O-N 2.66Å; Y409-T411 VanDerWaalsContact C-N 3.27Å; Y409-T411 PolarHBondContact O-N 2.9Å; Y409-H412 PolarHBondContact O-N 2.73Å; Y409-H412 VanDerWaalsContact O-N 3.09Å; Y409-T413 HydrophobicContact CD1-CG2 4.17Å; Y409-T413 HydrophobicContact CE1-CG2 3.65Å; Y409-T413 HydrophobicContact CE2-CG2 4.32Å; Y409-T413 PolarHBondContact O-N 3.18Å; Y409-T413 VanDerWaalsContact O-N 3.11Å; Y409-T413 PolarHBondContact O-OG1 3.46Å
410F86.8Confident91.5Very high39 Ų3912.8 Ų12.817%0.1716%0.059CC..Hα-helixtrans-63.1-29.7178.8-167-106.8000113.3D406 G407 Y408 H412 S414 D415 W418 R422D406-F410 WeakPolarHBondContact O-CB 3.42Å; D406-F410 PolarHBondContact O-N 2.86Å; G407-F410 CarbonylContact O-C 3.57Å; G407-F410 WeakPolarHBondContact O-CA 3.14Å; G407-F410 WeakPolarHBondContact O-CB 3.5Å; G407-F410 PolarHBondContact O-N 3.41Å; G407-F410 VanDerWaalsContact O-N 3.09Å; Y408-F410 VanDerWaalsContact C-N 3.29Å; Y408-F410 PolarHBondContact O-N 2.91Å; F410-H412 VanDerWaalsContact C-N 3.33Å; F410-S414 VanDerWaalsContact CD2-CB 3.5Å; F410-S414 WeakPolarHBondContact CD2-OG 3.36Å; F410-S414 VanDerWaalsContact CE2-OG 3.27Å; F410-S414 WeakPolarHBondContact CE2-OG 3.39Å; F410-S414 WeakPolarHBondContact O-CA 3.46Å; F410-S414 WeakPolarHBondContact O-CB 2.95Å; F410-S414 PolarHBondContact O-N 2.57Å; F410-D415 HydrophobicContact CD1-CB 4.07Å; F410-D415 HydrophobicContact CE1-CB 3.55Å; F410-D415 HydrophobicContact CZ-CB 4.31Å; F410-D415 PolarHBondContact O-N 3.02Å; F410-W418 HydrophobicContact CD1-CB 3.68Å; F410-W418 AromaticContact CD1-CD1 3.92Å; F410-W418 AromaticContact CD1-CD2 3.66Å; F410-W418 HydrophobicContact CD1-CD2 3.66Å; F410-W418 HydrophobicContact CD1-CE3 4.1Å; F410-W418 AromaticContact CD1-CG 3.46Å; F410-W418 HydrophobicContact CD1-CG 3.46Å; F410-W418 VanDerWaalsContact CD1-CG 3.46Å; F410-W418 HydrophobicContact CE1-CB 4.18Å; F410-W418 AromaticContact CE1-CD2 3.69Å; F410-W418 HydrophobicContact CE1-CD2 3.69Å; F410-W418 AromaticContact CE1-CE3 3.62Å; F410-W418 HydrophobicContact CE1-CE3 3.62Å; F410-W418 AromaticContact CE1-CG 3.95Å; F410-W418 HydrophobicContact CE1-CG 3.95Å; F410-W418 HydrophobicContact CE1-CZ3 4.28Å; F410-R422 HydrophobicContact CB-CG 4.43Å
411T84.8Confident91.4Very high4 Ų412.8 Ų12.83%0.0256%0.059CC..Hα-helixtrans-70.9-26.1173.962.70000114.3W365 G407 Y408 Y409 D415 R416 W418W365-T411 PolarHBondContact NE1-OG1 3.01Å; G407-T411 WeakPolarHBondContact O-CG2 3.46Å; G407-T411 PolarHBondContact O-N 3.12Å; Y408-T411 PolarHBondContact O-N 3.48Å; Y408-T411 VanDerWaalsContact O-N 3.13Å; Y408-T411 PolarHBondContact O-OG1 3.35Å; Y409-T411 VanDerWaalsContact C-N 3.27Å; Y409-T411 PolarHBondContact O-N 2.9Å; T411-D415 VanDerWaalsContact CA-O 3.31Å; T411-D415 WeakPolarHBondContact CA-O 3.29Å; T411-R416 WeakPolarHBondContact O-CA 3.37Å; T411-W418 HydrophobicContact CG2-CB 3.96Å; T411-W418 WeakPolarHBondContact CG2-O 3.39Å
412H82.6Confident91.3Very high42 Ų4214.1 Ų14.119%0.1946%0.064CC..Hα-helixtrans-83.1-35.7176.7-80.6-105.1000111.9M284 H305 W365 Y408 Y409 F410M284-H412 VanDerWaalsContact CE-CE1 3.46Å; M284-H412 WeakPolarHBondContact CE-CE1 3.27Å; H305-H412 PolarHBondContact O-CE1 2.66Å; H305-H412 VanDerWaalsContact O-CE1 3.29Å; H305-H412 PolarHBondContact O-NE2 2.79Å; W365-H412 AromaticContact CE2-CD2 3.76Å; W365-H412 AromaticContact CE2-NE2 3.44Å; W365-H412 AromaticContact CH2-CD2 3.93Å; W365-H412 AromaticContact CH2-CE1 3.56Å; W365-H412 AromaticContact CH2-ND1 3.89Å; W365-H412 AromaticContact CH2-NE2 3.61Å; W365-H412 AromaticContact CZ2-CD2 3.24Å; W365-H412 WeakPolarHBondContact CZ2-CD2 3.21Å; W365-H412 AromaticContact CZ2-CE1 3.63Å; W365-H412 AromaticContact CZ2-CG 3.75Å; W365-H412 AromaticContact CZ2-NE2 3.16Å; W365-H412 WeakPolarHBondContact CZ2-NE2 3.07Å; W365-H412 AromaticContact NE1-NE2 3.95Å; Y408-H412 AromaticContact CE1-CD2 3.91Å; Y408-H412 AromaticContact CE1-NE2 3.52Å; Y408-H412 AromaticContact CE2-NE2 3.78Å; Y408-H412 AromaticContact CZ-CD2 3.93Å; Y408-H412 AromaticContact CZ-NE2 3.23Å; Y408-H412 PolarHBondContact O-CD2 3.26Å; Y408-H412 PolarHBondContact O-N 3.29Å; Y408-H412 PolarHBondContact OH-NE2 3.11Å; Y409-H412 PolarHBondContact O-N 2.73Å; Y409-H412 VanDerWaalsContact O-N 3.09Å; F410-H412 VanDerWaalsContact C-N 3.33Å
413T76.5Confident90.9Very high24 Ų2416.7 Ų16.715%0.1478%0.075CC..Hα-helixtrans-90.3-48.3-177.259.90000112.1D118 Y409D118-T413 WeakPolarHBondContact CB-O 3.43Å; D118-T413 VanDerWaalsContact CG-O 3.25Å; Y409-T413 HydrophobicContact CD1-CG2 4.17Å; Y409-T413 HydrophobicContact CE1-CG2 3.65Å; Y409-T413 HydrophobicContact CE2-CG2 4.32Å; Y409-T413 PolarHBondContact O-N 3.18Å; Y409-T413 VanDerWaalsContact O-N 3.11Å; Y409-T413 PolarHBondContact O-OG1 3.46Å
414S75.3Confident90.4Very high13 Ų1319 Ų199%0.0919%0.09CC..THydrogen-bonded Turntrans-118.2-67.3-157.5-47.20000112.9D118 F410D118-S414 VanDerWaalsContact OD2-CA 3.26Å; D118-S414 WeakPolarHBondContact OD2-CA 3.44Å; D118-S414 WeakPolarHBondContact OD2-CB 2.88Å; D118-S414 PolarHBondContact OD2-OG 2.69Å; F410-S414 VanDerWaalsContact CD2-CB 3.5Å; F410-S414 WeakPolarHBondContact CD2-OG 3.36Å; F410-S414 VanDerWaalsContact CE2-OG 3.27Å; F410-S414 WeakPolarHBondContact CE2-OG 3.39Å; F410-S414 WeakPolarHBondContact O-CA 3.46Å; F410-S414 WeakPolarHBondContact O-CB 2.95Å; F410-S414 PolarHBondContact O-N 2.57Å
415D81.4Confident89.7Confident13 Ų1319.5 Ų19.57%0.079%0.092CC..  trans-129.199.2-172.6-174.8-15.1000110.1K198 F200 F410 T411 M417 W418K198-D415 HydrophobicContact CD-CB 4.36Å; K198-D415 IonicContact NZ-OD2 3.85Å; K198-D415 PolarHBondContact NZ-OD2 3.39Å; F200-D415 WeakPolarHBondContact CZ-OD1 3.14Å; F410-D415 HydrophobicContact CD1-CB 4.07Å; F410-D415 HydrophobicContact CE1-CB 3.55Å; F410-D415 HydrophobicContact CZ-CB 4.31Å; F410-D415 PolarHBondContact O-N 3.02Å; T411-D415 VanDerWaalsContact CA-O 3.31Å; T411-D415 WeakPolarHBondContact CA-O 3.29Å; D415-M417 PolarHBondContact O-N 3.23Å; D415-M417 VanDerWaalsContact O-N 3.08Å; D415-M417 WeakPolarHBondContact OD1-CA 3.38Å; D415-M417 WeakPolarHBondContact OD1-CB 3.49Å; D415-M417 PolarHBondContact OD1-N 2.68Å; D415-W418 HydrophobicContact CB-CB 4.21Å; D415-W418 WeakPolarHBondContact O-CB 3.32Å; D415-W418 PolarHBondContact O-N 3.29Å; D415-W418 PolarHBondContact OD1-N 3.18Å
416R90.6Very high89Confident4 Ų425.4 Ų25.42%0.01513%0.131CC..THydrogen-bonded Turntrans-60.3-20-179.3-177.152.4-176.988.8-1.5113.8L277 E280 R363 W365 T411 F571 L572L277-R416 HydrophobicContact CD2-CB 3.98Å; L277-R416 HydrophobicContact CD2-CG 3.35Å; E280-R416 IonicContact OE1-CZ 3.08Å; E280-R416 IonicContact OE1-NE 3.65Å; E280-R416 PolarHBondContact OE1-NE 3.37Å; E280-R416 IonicContact OE1-NH2 3.91Å; E280-R416 IonicContact OE2-CZ 3.98Å; E280-R416 IonicContact OE2-NE 3.95Å; E280-R416 PolarHBondContact OE2-NE 3.37Å; E280-R416 IonicContact OE2-NH2 3.74Å; E280-R416 PolarHBondContact OE2-NH2 2.84Å; R363-R416 PolarHBondContact O-NH1 3.26Å; W365-R416 VanDerWaalsContact CE2-NE 3.33Å; T411-R416 WeakPolarHBondContact O-CA 3.37Å; R416-F571 PolarHBondContact NH2-O 3.25Å; R416-L572 HydrophobicContact CG-CD2 4.26Å
417M90.7Very high88.1Confident5 Ų529.4 Ų29.43%0.02517%0.172CC..THydrogen-bonded Turntrans-93.22.7178-63.7-60.5114.200113.2F200 W233 L277 R363 D415 R419 L572F200-M417 HydrophobicContact CD1-CG 4.39Å; F200-M417 HydrophobicContact CE1-CB 4.21Å; F200-M417 HydrophobicContact CE1-CG 3.65Å; F200-M417 HydrophobicContact CE2-CG 4.3Å; F200-M417 HydrophobicContact CZ-CB 4Å; F200-M417 HydrophobicContact CZ-CG 3.59Å; W233-M417 HydrophobicContact CH2-SD 4.34Å; W233-M417 HydrophobicContact CZ2-CE 4.4Å; W233-M417 HydrophobicContact CZ2-SD 3.44Å; W233-M417 WeakPolarHBondContact CZ2-SD 3.23Å; L277-M417 HydrophobicContact CD2-CE 4.35Å; R363-M417 WeakPolarHBondContact CD-O 3.32Å; R363-M417 PolarHBondContact NH1-O 2.63Å; D415-M417 PolarHBondContact O-N 3.23Å; D415-M417 VanDerWaalsContact O-N 3.08Å; D415-M417 WeakPolarHBondContact OD1-CA 3.38Å; D415-M417 WeakPolarHBondContact OD1-CB 3.49Å; D415-M417 PolarHBondContact OD1-N 2.68Å; M417-R419 PolarHBondContact O-N 2.75Å; M417-L572 HydrophobicContact CE-CD1 4.23Å; M417-L572 HydrophobicContact CE-CD2 3.54Å; M417-L572 HydrophobicContact CE-CG 4.02Å
418W92.4Very high87.4Confident31 Ų3134.9 Ų34.912%0.11719%0.193CC..  trans-64.8133179.6-167.9-97.1000112.1S362 R363 F410 T411 D415 K420 T421 R422 Y431S362-W418 PolarHBondContact OG-O 3.34Å; R363-W418 VanDerWaalsContact CB-O 3.26Å; R363-W418 WeakPolarHBondContact CB-O 3.35Å; R363-W418 PolarHBondContact N-O 2.85Å; F410-W418 HydrophobicContact CD1-CB 3.68Å; F410-W418 AromaticContact CD1-CD1 3.92Å; F410-W418 AromaticContact CD1-CD2 3.66Å; F410-W418 HydrophobicContact CD1-CD2 3.66Å; F410-W418 HydrophobicContact CD1-CE3 4.1Å; F410-W418 AromaticContact CD1-CG 3.46Å; F410-W418 HydrophobicContact CD1-CG 3.46Å; F410-W418 VanDerWaalsContact CD1-CG 3.46Å; F410-W418 HydrophobicContact CE1-CB 4.18Å; F410-W418 AromaticContact CE1-CD2 3.69Å; F410-W418 HydrophobicContact CE1-CD2 3.69Å; F410-W418 AromaticContact CE1-CE3 3.62Å; F410-W418 HydrophobicContact CE1-CE3 3.62Å; F410-W418 AromaticContact CE1-CG 3.95Å; F410-W418 HydrophobicContact CE1-CG 3.95Å; F410-W418 HydrophobicContact CE1-CZ3 4.28Å; T411-W418 HydrophobicContact CG2-CB 3.96Å; T411-W418 WeakPolarHBondContact CG2-O 3.39Å; D415-W418 HydrophobicContact CB-CB 4.21Å; D415-W418 WeakPolarHBondContact O-CB 3.32Å; D415-W418 PolarHBondContact O-N 3.29Å; D415-W418 PolarHBondContact OD1-N 3.18Å; W418-K420 VanDerWaalsContact CD1-O 3.28Å; W418-K420 HydrophobicContact CZ2-CB 4.29Å; W418-K420 PolarHBondContact NE1-O 2.88Å; W418-T421 WeakPolarHBondContact CZ2-O 2.94Å; W418-T421 PolarHBondContact NE1-O 2.89Å; W418-R422 VanDerWaalsContact CZ2-NH1 3.3Å; W418-Y431 WeakPolarHBondContact CH2-O 3.46Å; W418-Y431 WeakPolarHBondContact CZ2-O 3.37Å
419R95.8Very high86.3Confident23 Ų2338.5 Ų38.59%0.08722%0.219CC..  trans-107.7-47.3-177.6179.4-174.7168.585.2-7.6112.6H361 S362 E364 N404 M417 D434 E455H361-R419 WeakPolarHBondContact CA-O 3.39Å; H361-R419 HydrophobicContact CB-CG 3.96Å; H361-R419 PolarHBondContact CE1-NH1 2.81Å; H361-R419 VanDerWaalsContact CE1-NH1 3.26Å; H361-R419 PolarHBondContact CE1-NH2 3.36Å; H361-R419 VanDerWaalsContact ND1-CZ 3.34Å; H361-R419 PolarHBondContact ND1-NH1 3.38Å; H361-R419 VanDerWaalsContact NE2-CZ 3.32Å; H361-R419 PolarHBondContact NE2-NH2 2.82Å; H361-R419 VanDerWaalsContact NE2-NH2 3.13Å; S362-R419 PolarHBondContact N-O 2.7Å; S362-R419 VanDerWaalsContact N-O 3.15Å; S362-R419 PolarHBondContact OG-O 3.38Å; S362-R419 VanDerWaalsContact OG-O 3.08Å; E364-R419 IonicContact OE1-NH1 3.26Å; E364-R419 PolarHBondContact OE1-NH1 2.93Å; N404-R419 PolarHBondContact ND2-O 3.13Å; M417-R419 PolarHBondContact O-N 2.75Å; R419-D434 IonicContact CZ-OD2 3.89Å; R419-D434 IonicContact NE-OD2 3.45Å; R419-D434 PolarHBondContact NE-OD2 2.9Å; R419-D434 VanDerWaalsContact NE-OD2 3.09Å; R419-D434 IonicContact NH2-OD1 3.28Å; R419-D434 IonicContact NH2-OD2 3.45Å; R419-D434 PolarHBondContact NH2-OD2 3.37Å; R419-E455 WeakPolarHBondContact CB-OE2 3.46Å
420K97.2Very high85.7Confident2 Ų237.4 Ų37.41%0.00922%0.219CC..SBendtrans-76178.7-164.1-66.1-167.1-67175.60114.1N404 W418 Y431 G432 V433 P452 S454N404-K420 VanDerWaalsContact ND2-C 3.35Å; N404-K420 PolarHBondContact ND2-O 2.86Å; W418-K420 VanDerWaalsContact CD1-O 3.28Å; W418-K420 HydrophobicContact CZ2-CB 4.29Å; W418-K420 PolarHBondContact NE1-O 2.88Å; K420-Y431 VanDerWaalsContact CE-O 3.28Å; K420-Y431 WeakPolarHBondContact CE-O 3.47Å; K420-Y431 PolarHBondContact NZ-O 3.13Å; K420-Y431 VanDerWaalsContact NZ-O 3.12Å; K420-G432 PolarHBondContact NZ-O 3.05Å; K420-V433 WeakPolarHBondContact CA-O 3.43Å; K420-V433 VanDerWaalsContact CB-O 3.28Å; K420-V433 WeakPolarHBondContact CB-O 3.37Å; K420-P452 PolarHBondContact NZ-O 3.29Å; K420-P452 VanDerWaalsContact NZ-O 3.17Å; K420-S454 WeakPolarHBondContact CD-O 3.45Å; K420-S454 PolarHBondContact NZ-O 3.05Å
421T97.8Very high85.8Confident0 Ų038.9 Ų38.90%022%0.224CC..  trans-66-177.9163.863.60000111.1W418 G432 V433 P435 E465W418-T421 WeakPolarHBondContact CZ2-O 2.94Å; W418-T421 PolarHBondContact NE1-O 2.89Å; T421-G432 WeakPolarHBondContact O-CA 3.09Å; T421-G432 WeakPolarHBondContact OG1-CA 3.43Å; T421-V433 PolarHBondContact N-O 3.05Å; T421-V433 PolarHBondContact OG1-N 3.36Å; T421-V433 PolarHBondContact OG1-O 3.37Å; T421-P435 HydrophobicContact CG2-CB 4.04Å; T421-P435 HydrophobicContact CG2-CG 4.3Å; T421-E465 WeakPolarHBondContact CB-OE2 3.35Å; T421-E465 HydrophobicContact CG2-CB 4.22Å; T421-E465 HydrophobicContact CG2-CG 4.04Å; T421-E465 PolarHBondContact OG1-OE2 2.84Å
422R95.8Very high86.2Confident29 Ų2938.7 Ų38.711%0.10922%0.223CC..  trans-115.510-179-70.3-62.9-57.1157.40.9115E335 D406 F410 W418E335-R422 HydrophobicContact CG-CB 4.4Å; E335-R422 WeakPolarHBondContact OE1-CB 3.39Å; E335-R422 IonicContact OE1-NE 2.77Å; D406-R422 HydrophobicContact CB-CB 3.84Å; D406-R422 HydrophobicContact CB-CG 3.77Å; F410-R422 HydrophobicContact CB-CG 4.43Å; W418-R422 VanDerWaalsContact CZ2-NH1 3.3Å
423K90.9Very high86.9Confident59 Ų5936.7 Ų36.726%0.25721%0.214SC..  trans-64.7127176.8-175.9172.4-179.3-172.20111.6Y334 G432 S464 E465Y334-K423 HydrophobicContact CD1-CB 4.3Å; Y334-K423 HydrophobicContact CD2-CB 3.85Å; Y334-K423 HydrophobicContact CD2-CD 4Å; Y334-K423 HydrophobicContact CD2-CG 3.62Å; Y334-K423 HydrophobicContact CE2-CB 4.28Å; Y334-K423 HydrophobicContact CE2-CD 4.27Å; Y334-K423 HydrophobicContact CE2-CG 3.67Å; Y334-K423 HydrophobicContact CG-CB 3.86Å; Y334-K423 HydrophobicContact CG-CG 4.16Å; K423-G432 PolarHBondContact O-N 3.35Å; K423-S464 PolarHBondContact NZ-O 3.48Å; K423-E465 IonicContact NZ-OE1 2.81Å
424P87.5Confident87.9Confident51 Ų5135.5 Ų35.533%0.33121%0.207SC..BIsolated β-bridgetrans-62.1139.1174.1-17.627.2000111.7Y334 P426 Y431Y334-P424 HydrophobicContact CE1-CG 4.1Å; Y334-P424 VanDerWaalsContact OH-CD 3.28Å; Y334-P424 WeakPolarHBondContact OH-CD 3.31Å; P424-P426 WeakPolarHBondContact O-CD 3.44Å; P424-Y431 HydrophobicContact CB-CD1 4.09Å; P424-Y431 HydrophobicContact CB-CE1 3.91Å; P424-Y431 HydrophobicContact CG-CD1 4Å; P424-Y431 HydrophobicContact CG-CE1 3.73Å
425N84.2Confident89Confident11 Ų1135 Ų356%0.05920%0.203CC..  trans-96.2112.6174.5-64.4-53.7000110.1G427 Y428 C430 G432 P452 Y457N425-G427 PolarHBondContact O-N 3.11Å; N425-Y428 PolarHBondContact O-N 3.29Å; N425-Y428 VanDerWaalsContact O-N 3.11Å; N425-C430 WeakPolarHBondContact CB-O 3.38Å; N425-C430 PolarHBondContact ND2-O 3.02Å; N425-G432 PolarHBondContact ND2-O 3.3Å; N425-G432 VanDerWaalsContact ND2-O 3.12Å; N425-P452 HydrophobicContact CB-CB 3.9Å; N425-Y457 WeakPolarHBondContact OD1-CE1 3.44Å
426P83.1Confident89.8Confident124 Ų12435.1 Ų35.181%0.80520%0.204SC*.THydrogen-bonded Turntrans-56.8130.7-176.5-2634.9000112.7P424 Y428P424-P426 WeakPolarHBondContact O-CD 3.44Å; P426-Y428 VanDerWaalsContact C-N 3.33Å
427G77.4Confident90.2Very high83 Ų8335.2 Ų35.286%0.85620%0.204SC*.THydrogen-bonded Turntrans83.90.9-179.800000115.2N425N425-G427 PolarHBondContact O-N 3.11Å
428Y76.6Confident90.6Very high116 Ų11635 Ų3546%0.45520%0.203SC..SBendtrans-126.5154.1176.6-65.8-94.6000110.6N425 P426 C430 Y451 P452N425-Y428 PolarHBondContact O-N 3.29Å; N425-Y428 VanDerWaalsContact O-N 3.11Å; P426-Y428 VanDerWaalsContact C-N 3.33Å; Y428-C430 VanDerWaalsContact C-N 3.25Å; Y428-Y451 HydrophobicContact CD1-CE2 4.37Å; Y428-Y451 HydrophobicContact CE1-CD2 4.3Å; Y428-Y451 AromaticContact CE1-CE2 3.89Å; Y428-Y451 HydrophobicContact CE1-CE2 3.89Å; Y428-P452 HydrophobicContact CD1-CB 4.28Å; Y428-P452 HydrophobicContact CD1-CG 4.3Å; Y428-P452 HydrophobicContact CD2-CB 3.98Å; Y428-P452 HydrophobicContact CD2-CG 3.69Å; Y428-P452 HydrophobicContact CE1-CG 4.21Å; Y428-P452 HydrophobicContact CE2-CB 4.37Å; Y428-P452 HydrophobicContact CE2-CG 3.6Å; Y428-P452 HydrophobicContact CG-CB 3.93Å; Y428-P452 HydrophobicContact CG-CG 4.05Å
429S74.6Confident90.9Very high79 Ų7933.5 Ų33.555%0.55220%0.197SC*.SBendtrans-77.9-12.1171.950.60000113.1Y431S429-Y431 WeakPolarHBondContact O-CD2 3.46Å; S429-Y431 WeakPolarHBondContact O-CE2 3.4Å
430C77.4Confident91Very high34 Ų3436.8 Ų36.823%0.2322%0.216CC..  trans-92145.8-173.7-53.70000112.2N425 Y428 C453N425-C430 WeakPolarHBondContact CB-O 3.38Å; N425-C430 PolarHBondContact ND2-O 3.02Å; Y428-C430 VanDerWaalsContact C-N 3.25Å; C430-C453 HydrophobicContact CB-CB 3.7Å; C430-C453 WeakPolarHBondContact CB-SG 3.47Å; C430-C453 VanDerWaalsContact SG-CA 3.56Å; C430-C453 WeakPolarHBondContact SG-CB 3.46Å; C430-C453 CovalentContact SG-SG 2.03Å; C430-C453 PolarHBondContact SG-SG 2.99Å
431Y89.9Confident91.1Very high69 Ų6936.7 Ų36.727%0.27122%0.216SC..BIsolated β-bridgetrans-109.4157.6-177.8-68.6-112.6000110.4W418 K420 P424 S429W418-Y431 WeakPolarHBondContact CH2-O 3.46Å; W418-Y431 WeakPolarHBondContact CZ2-O 3.37Å; K420-Y431 VanDerWaalsContact CE-O 3.28Å; K420-Y431 WeakPolarHBondContact CE-O 3.47Å; K420-Y431 PolarHBondContact NZ-O 3.13Å; K420-Y431 VanDerWaalsContact NZ-O 3.12Å; P424-Y431 HydrophobicContact CB-CD1 4.09Å; P424-Y431 HydrophobicContact CB-CE1 3.91Å; P424-Y431 HydrophobicContact CG-CD1 4Å; P424-Y431 HydrophobicContact CG-CE1 3.73Å; S429-Y431 WeakPolarHBondContact O-CD2 3.46Å; S429-Y431 WeakPolarHBondContact O-CE2 3.4Å
432G92Very high91.1Very high0 Ų037.6 Ų37.60%023%0.226CC..  trans81154.8167.800000114.7K420 T421 K423 N425K420-G432 PolarHBondContact NZ-O 3.05Å; T421-G432 WeakPolarHBondContact O-CA 3.09Å; T421-G432 WeakPolarHBondContact OG1-CA 3.43Å; K423-G432 PolarHBondContact O-N 3.35Å; N425-G432 PolarHBondContact ND2-O 3.3Å; N425-G432 VanDerWaalsContact ND2-O 3.12Å
433V97.1Very high91.2Very high0 Ų038.8 Ų38.80%023%0.232CC..  trans-114.5148.8169.9171.50000107.3K420 T421 P435 N438 Y457 H458 E465K420-V433 WeakPolarHBondContact CA-O 3.43Å; K420-V433 VanDerWaalsContact CB-O 3.28Å; K420-V433 WeakPolarHBondContact CB-O 3.37Å; T421-V433 PolarHBondContact N-O 3.05Å; T421-V433 PolarHBondContact OG1-N 3.36Å; T421-V433 PolarHBondContact OG1-O 3.37Å; V433-P435 WeakPolarHBondContact O-CD 3.47Å; V433-N438 HydrophobicContact CG1-CB 3.98Å; V433-Y457 HydrophobicContact CB-CD1 4.42Å; V433-Y457 WeakPolarHBondContact CG1-O 3.39Å; V433-Y457 HydrophobicContact CG2-CD1 3.82Å; V433-Y457 HydrophobicContact CG2-CE1 3.77Å; V433-H458 WeakPolarHBondContact CG1-O 3.2Å; V433-E465 VanDerWaalsContact CB-CD 3.42Å; V433-E465 HydrophobicContact CB-CG 3.65Å; V433-E465 HydrophobicContact CG1-CG 3.78Å; V433-E465 VanDerWaalsContact CG2-CD 3.46Å; V433-E465 HydrophobicContact CG2-CG 4.18Å; V433-E465 WeakPolarHBondContact CG2-OE1 3.37Å
434D98.3Very high91.2Very high0 Ų037.8 Ų37.80%024%0.238CC..  trans-68.8109.5167.4-175-33.3000108.2H361 R419 N436 R437 N438 E455 Y457H361-D434 IonicContact CD2-OD1 3.75Å; H361-D434 IonicContact NE2-OD1 3.83Å; H361-D434 PolarHBondContact NE2-OD1 3.43Å; H361-D434 VanDerWaalsContact NE2-OD1 3.08Å; H361-D434 IonicContact NE2-OD2 3.26Å; R419-D434 IonicContact CZ-OD2 3.89Å; R419-D434 IonicContact NE-OD2 3.45Å; R419-D434 PolarHBondContact NE-OD2 2.9Å; R419-D434 VanDerWaalsContact NE-OD2 3.09Å; R419-D434 IonicContact NH2-OD1 3.28Å; R419-D434 IonicContact NH2-OD2 3.45Å; R419-D434 PolarHBondContact NH2-OD2 3.37Å; D434-N436 PolarHBondContact O-N 3.04Å; D434-N436 VanDerWaalsContact O-N 3.17Å; D434-N436 WeakPolarHBondContact OD1-CA 3.25Å; D434-N436 PolarHBondContact OD1-N 2.9Å; D434-R437 HydrophobicContact CB-CB 4.02Å; D434-R437 HydrophobicContact CB-CG 3.82Å; D434-R437 PolarHBondContact O-N 2.75Å; D434-R437 PolarHBondContact OD1-N 2.86Å; D434-N438 PolarHBondContact O-N 2.84Å; D434-E455 WeakPolarHBondContact CB-O 3.27Å; D434-Y457 PolarHBondContact N-O 3.33Å
435P98.4Very high91.5Very high1 Ų139.4 Ų39.41%0.00624%0.243CC..THydrogen-bonded Turntrans-65.6-19-176.126.8-32.6000112.8I360 T421 V433 W439 V468I360-P435 HydrophobicContact CD1-CB 4.17Å; I360-P435 HydrophobicContact CG1-CB 3.72Å; I360-P435 HydrophobicContact CG1-CG 3.76Å; I360-P435 WeakPolarHBondContact O-CG 3.46Å; T421-P435 HydrophobicContact CG2-CB 4.04Å; T421-P435 HydrophobicContact CG2-CG 4.3Å; V433-P435 WeakPolarHBondContact O-CD 3.47Å; P435-W439 VanDerWaalsContact O-CD1 3.23Å; P435-W439 PolarHBondContact O-NE1 2.95Å; P435-V468 HydrophobicContact CB-CG2 4.01Å; P435-V468 WeakPolarHBondContact O-CG2 3.23Å
436N98.6Very high91.6Very high17 Ų1742.7 Ų42.79%0.09127%0.265CS..THydrogen-bonded Turntrans-98.521.5173.4-16016.4000112.8H361 D434 H488 G544 S545 T546H361-N436 WeakPolarHBondContact NE2-CB 3.44Å; D434-N436 PolarHBondContact O-N 3.04Å; D434-N436 VanDerWaalsContact O-N 3.17Å; D434-N436 WeakPolarHBondContact OD1-CA 3.25Å; D434-N436 PolarHBondContact OD1-N 2.9Å; N436-H488 PolarHBondContact ND2-NE2 3.42Å; N436-H488 VanDerWaalsContact ND2-NE2 3.1Å; N436-G544 CarbonylContact C-O 3.57Å; N436-S545 VanDerWaalsContact OD1-CA 3.25Å; N436-S545 WeakPolarHBondContact OD1-CA 3.31Å; N436-S545 WeakPolarHBondContact OD1-CB 3.2Å; N436-T546 PolarHBondContact OD1-N 3.13Å; N436-T546 PolarHBondContact OD1-OG1 2.86Å
437R98.4Very high91.6Very high5 Ų538.2 Ų38.22%0.01924%0.242CC..SBendtrans-123.2-0.9162.6-61-61.4-176.6-83.9-4.5112.8D434 G447 A448 H458 Y540 S543 G544D434-R437 HydrophobicContact CB-CB 4.02Å; D434-R437 HydrophobicContact CB-CG 3.82Å; D434-R437 PolarHBondContact O-N 2.75Å; D434-R437 PolarHBondContact OD1-N 2.86Å; R437-G447 PolarHBondContact NE-O 3.43Å; R437-A448 HydrophobicContact CB-CB 4.12Å; R437-A448 HydrophobicContact CG-CB 4.07Å; R437-H458 HydrophobicContact CB-CB 4.05Å; R437-Y540 PolarHBondContact NH2-OH 3.36Å; R437-S543 WeakPolarHBondContact CD-O 3.43Å; R437-G544 CarbonylContact C-O 3.54Å; R437-G544 WeakPolarHBondContact CA-O 3.31Å; R437-G544 PolarHBondContact N-O 3.36Å
438N98.8Very high92.1Very high0 Ų035.3 Ų35.30%021%0.209CC..  trans-95.32.1-171.6-163.4-115.5000113.9V433 D434 H458 S461 A462 H463 S464 E465 V468 G544V433-N438 HydrophobicContact CG1-CB 3.98Å; D434-N438 PolarHBondContact O-N 2.84Å; N438-H458 PolarHBondContact ND2-O 3.34Å; N438-S461 PolarHBondContact ND2-O 3.23Å; N438-S461 VanDerWaalsContact ND2-O 3.11Å; N438-A462 CarbonylContact O-C 3.58Å; N438-A462 WeakPolarHBondContact O-CA 3.49Å; N438-H463 PolarHBondContact O-N 2.64Å; N438-H463 VanDerWaalsContact OD1-CA 3.24Å; N438-H463 WeakPolarHBondContact OD1-CA 3.12Å; N438-H463 PolarHBondContact OD1-N 3.32Å; N438-S464 PolarHBondContact ND2-OG 3.17Å; N438-S464 PolarHBondContact OD1-N 3.32Å; N438-E465 HydrophobicContact CB-CG 4.35Å; N438-E465 PolarHBondContact OD1-N 3.45Å; N438-E465 VanDerWaalsContact OD1-N 3.11Å; N438-V468 HydrophobicContact CB-CG2 4.34Å; N438-G544 PolarHBondContact N-O 3.45Å
439W98.8Very high92.6Very high0 Ų030 Ų300%019%0.189CC..SBendtrans-83.9150.8-177.5-58.976.6000112.1I360 P435 A441 V468 I471 V472 G544 T546 W549I360-W439 HydrophobicContact CD1-CZ2 4.25Å; P435-W439 VanDerWaalsContact O-CD1 3.23Å; P435-W439 PolarHBondContact O-NE1 2.95Å; W439-A441 PolarHBondContact O-N 3.26Å; W439-V468 HydrophobicContact CD2-CG1 3.72Å; W439-V468 HydrophobicContact CE3-CG1 4.06Å; W439-V468 HydrophobicContact CG-CG1 4.17Å; W439-V468 HydrophobicContact CH2-CG1 4.33Å; W439-V468 HydrophobicContact CZ2-CG1 3.99Å; W439-V468 HydrophobicContact CZ2-CG2 4.41Å; W439-V468 HydrophobicContact CZ3-CG1 4.35Å; W439-I471 HydrophobicContact CH2-CB 3.86Å; W439-I471 HydrophobicContact CH2-CD1 4.12Å; W439-I471 HydrophobicContact CH2-CG2 3.76Å; W439-I471 HydrophobicContact CZ2-CD1 4.27Å; W439-I471 HydrophobicContact CZ3-CG2 4.4Å; W439-V472 HydrophobicContact CE3-CG2 3.85Å; W439-V472 HydrophobicContact CZ3-CG2 3.64Å; W439-G544 WeakPolarHBondContact CB-O 3.47Å; W439-G544 VanDerWaalsContact CD1-O 3.25Å; W439-G544 PolarHBondContact N-O 3.43Å; W439-G544 VanDerWaalsContact O-CA 3.25Å; W439-G544 WeakPolarHBondContact O-CA 3.27Å; W439-T546 HydrophobicContact CD2-CG2 4.42Å; W439-T546 VanDerWaalsContact CE2-OG1 3.28Å; W439-T546 HydrophobicContact CH2-CG2 3.81Å; W439-T546 HydrophobicContact CZ2-CG2 3.56Å; W439-T546 HydrophobicContact CZ3-CG2 4.35Å; W439-T546 PolarHBondContact NE1-OG1 3.3Å; W439-W549 HydrophobicContact CB-CB 3.88Å; W439-W549 HydrophobicContact CB-CG 4.34Å; W439-W549 HydrophobicContact CE3-CB 4.11Å; W439-W549 AromaticContact CE3-CD2 3.67Å; W439-W549 HydrophobicContact CE3-CD2 3.67Å; W439-W549 AromaticContact CE3-CE3 3.43Å; W439-W549 HydrophobicContact CE3-CE3 3.43Å; W439-W549 VanDerWaalsContact CE3-CE3 3.43Å; W439-W549 AromaticContact CE3-CG 3.96Å; W439-W549 HydrophobicContact CE3-CG 3.96Å; W439-W549 HydrophobicContact CE3-CZ3 4.16Å; W439-W549 HydrophobicContact CZ3-CD2 4.08Å; W439-W549 AromaticContact CZ3-CE3 3.39Å; W439-W549 HydrophobicContact CZ3-CE3 3.39Å; W439-W549 AromaticContact CZ3-CZ3 3.68Å; W439-W549 HydrophobicContact CZ3-CZ3 3.68Å
440N98.6Very high93.3Very high92 Ų9230.6 Ų30.649%0.49219%0.194SC..SBendtrans-80.256.2-179.6-16947.2000113A462 H463N440-A462 HydrophobicContact CB-CB 3.71Å; N440-H463 WeakPolarHBondContact CB-CE1 3.42Å; N440-H463 WeakPolarHBondContact CB-NE2 3.18Å; N440-H463 PolarHBondContact N-NE2 3.45Å
441A98.3Very high93.7Very high1 Ų133.7 Ų33.71%0.00820%0.201CC..SBendtrans-135.3100.7173.700000109.1W439 F443 Y500 G544 D548 W549W439-A441 PolarHBondContact O-N 3.26Å; A441-F443 PolarHBondContact O-N 2.98Å; A441-Y500 HydrophobicContact CB-CE1 4.48Å; A441-G544 WeakPolarHBondContact O-CA 3.45Å; A441-G544 PolarHBondContact O-N 3Å; A441-D548 HydrophobicContact CB-CB 3.68Å; A441-W549 HydrophobicContact CB-CB 3.84Å
442G97.5Very high93.6Very high19 Ų1930.8 Ų30.820%0.19619%0.191CC..SBendtrans61.523.6-170.600000114.1G444 L445 S543G442-G444 PolarHBondContact O-N 2.67Å; G442-L445 WeakPolarHBondContact O-CB 3.39Å; G442-L445 WeakPolarHBondContact O-CG 3.33Å; G442-L445 PolarHBondContact O-N 3.04Å; G442-S543 VanDerWaalsContact O-CB 3.28Å; G442-S543 WeakPolarHBondContact O-CB 3.4Å
443F98.3Very high93.1Very high54 Ų5432.3 Ų32.324%0.23720%0.201CC..THydrogen-bonded Turntrans-47.6128.9-176.2179.6-93000113A441 L445 H458 S461 A462A441-F443 PolarHBondContact O-N 2.98Å; F443-L445 PolarHBondContact O-N 2.96Å; F443-H458 HydrophobicContact CE2-CB 3.99Å; F443-H458 WeakPolarHBondContact CE2-O 3.49Å; F443-H458 HydrophobicContact CZ-CB 4.23Å; F443-H458 AromaticContact CZ-ND1 3.67Å; F443-S461 VanDerWaalsContact CE2-C 3.49Å; F443-S461 VanDerWaalsContact CZ-CA 3.48Å; F443-A462 HydrophobicContact CB-CB 4.09Å; F443-A462 HydrophobicContact CD1-CB 4.3Å; F443-A462 HydrophobicContact CD2-CB 3.68Å; F443-A462 HydrophobicContact CE2-CB 4.17Å; F443-A462 HydrophobicContact CG-CB 3.75Å; F443-A462 VanDerWaalsContact CZ-N 3.28Å
444G91.6Very high92.4Very high38 Ų3833.5 Ų33.539%0.39221%0.209SC..THydrogen-bonded Turntrans75.41.3178.800000115.6G442G442-G444 PolarHBondContact O-N 2.67Å
445L92.9Very high91.7Very high85 Ų8536.2 Ų36.245%0.44522%0.222SC..SBendtrans-73.4172.1169.7-64.5-176.2000111.3G442 F443 Y500 S543G442-L445 WeakPolarHBondContact O-CB 3.39Å; G442-L445 WeakPolarHBondContact O-CG 3.33Å; G442-L445 PolarHBondContact O-N 3.04Å; F443-L445 PolarHBondContact O-N 2.96Å; L445-Y500 HydrophobicContact CD1-CD2 4.05Å; L445-S543 WeakPolarHBondContact O-CB 3.37Å; L445-S543 PolarHBondContact O-OG 2.8Å
446P88.1Confident91.2Very high80 Ų8038 Ų3852%0.51923%0.233SC..THydrogen-bonded Turntrans-51.9144.6177.7-28.837.2000113.2S543P446-S543 WeakPolarHBondContact O-CB 3.29Å
447G82.7Confident90.9Very high30 Ų3038.2 Ų38.231%0.30923%0.233SC..THydrogen-bonded Turntrans104.10.1-173.100000114.8R437 Q541R437-G447 PolarHBondContact NE-O 3.43Å; G447-Q541 WeakPolarHBondContact CA-O 3.38Å
448A87Confident90.8Very high21 Ų2139.2 Ų39.217%0.17424%0.238CC..SBendtrans-136.1159.3170.200000110.6R437 H458 S543R437-A448 HydrophobicContact CB-CB 4.12Å; R437-A448 HydrophobicContact CG-CB 4.07Å; A448-H458 HydrophobicContact CB-CB 3.88Å; A448-S543 WeakPolarHBondContact CB-OG 3.41Å
449S86.5Confident90.7Very high5 Ų539.2 Ų39.24%0.03524%0.238CC..BIsolated β-bridgetrans-101.6144.1175.3-175.90000111.4Y451 S454 T456 Y457 H458S449-Y451 WeakPolarHBondContact OG-CB 3.34Å; S449-Y451 PolarHBondContact OG-N 2.97Å; S449-Y451 VanDerWaalsContact OG-N 3.11Å; S449-S454 VanDerWaalsContact CB-CB 3.46Å; S449-S454 VanDerWaalsContact CB-OG 3.29Å; S449-S454 WeakPolarHBondContact CB-OG 3.32Å; S449-S454 WeakPolarHBondContact OG-CB 3.26Å; S449-T456 PolarHBondContact N-O 3.1Å; S449-Y457 CarbonylContact O-C 3.58Å; S449-Y457 VanDerWaalsContact O-CA 3.27Å; S449-Y457 WeakPolarHBondContact O-CA 3.14Å; S449-Y457 WeakPolarHBondContact O-CD2 3.46Å; S449-H458 VanDerWaalsContact C-CD2 3.42Å; S449-H458 PolarHBondContact O-CD2 3.46Å; S449-H458 PolarHBondContact O-N 3.49Å; S449-H458 PolarHBondContact O-NE2 3.33Å
450S89.6Confident90.6Very high92 Ų9243.7 Ų43.764%0.64327%0.266SS*.  trans-89.9-6.4169.360.70000113P452 Y457 H458S450-P452 WeakPolarHBondContact O-CD 3.25Å; S450-Y457 WeakPolarHBondContact O-CE2 3.48Å; S450-H458 VanDerWaalsContact CA-NE2 3.28Å; S450-H458 WeakPolarHBondContact CA-NE2 3.43Å; S450-H458 WeakPolarHBondContact CB-NE2 3.36Å
451Y87.3Confident90.6Very high99 Ų9942.1 Ų42.139%0.38826%0.263SS..SBendtrans-83.1118.5-179.8-178.6-129.5000111Y428 S449 C453 S454 Y457Y428-Y451 HydrophobicContact CD1-CE2 4.37Å; Y428-Y451 HydrophobicContact CE1-CD2 4.3Å; Y428-Y451 AromaticContact CE1-CE2 3.89Å; Y428-Y451 HydrophobicContact CE1-CE2 3.89Å; S449-Y451 WeakPolarHBondContact OG-CB 3.34Å; S449-Y451 PolarHBondContact OG-N 2.97Å; S449-Y451 VanDerWaalsContact OG-N 3.11Å; Y451-C453 HydrophobicContact CD1-CB 4.04Å; Y451-C453 HydrophobicContact CE1-CB 3.47Å; Y451-C453 VanDerWaalsContact CE1-CB 3.47Å; Y451-C453 HydrophobicContact CE2-CB 4.48Å; Y451-C453 PolarHBondContact O-N 3.14Å; Y451-C453 VanDerWaalsContact O-N 3.1Å; Y451-S454 WeakPolarHBondContact O-CB 3.43Å; Y451-S454 PolarHBondContact O-N 3.21Å; Y451-Y457 WeakPolarHBondContact O-CB 3.03Å
452P86.8Confident90.6Very high8 Ų843.3 Ų43.35%0.05227%0.272CS..THydrogen-bonded Turntrans-61.7-23.3-171.4-30.440.2000116.6K420 N425 Y428 S450 S454 Y457K420-P452 PolarHBondContact NZ-O 3.29Å; K420-P452 VanDerWaalsContact NZ-O 3.17Å; N425-P452 HydrophobicContact CB-CB 3.9Å; Y428-P452 HydrophobicContact CD1-CB 4.28Å; Y428-P452 HydrophobicContact CD1-CG 4.3Å; Y428-P452 HydrophobicContact CD2-CB 3.98Å; Y428-P452 HydrophobicContact CD2-CG 3.69Å; Y428-P452 HydrophobicContact CE1-CG 4.21Å; Y428-P452 HydrophobicContact CE2-CB 4.37Å; Y428-P452 HydrophobicContact CE2-CG 3.6Å; Y428-P452 HydrophobicContact CG-CB 3.93Å; Y428-P452 HydrophobicContact CG-CG 4.05Å; S450-P452 WeakPolarHBondContact O-CD 3.25Å; P452-S454 VanDerWaalsContact C-N 3.34Å; P452-Y457 HydrophobicContact CB-CD1 4.22Å; P452-Y457 HydrophobicContact CB-CE1 3.99Å; P452-Y457 HydrophobicContact CB-CE2 4.44Å; P452-Y457 HydrophobicContact CG-CE1 4.26Å; P452-Y457 HydrophobicContact CG-CE2 4.02Å
453C80.9Confident90.6Very high32 Ų3243.9 Ų43.922%0.21627%0.27CS..THydrogen-bonded Turntrans-83.2-9.6175.9-630000113.6C430 Y451C430-C453 HydrophobicContact CB-CB 3.7Å; C430-C453 WeakPolarHBondContact CB-SG 3.47Å; C430-C453 VanDerWaalsContact SG-CA 3.56Å; C430-C453 WeakPolarHBondContact SG-CB 3.46Å; C430-C453 CovalentContact SG-SG 2.03Å; C430-C453 PolarHBondContact SG-SG 2.99Å; Y451-C453 HydrophobicContact CD1-CB 4.04Å; Y451-C453 HydrophobicContact CE1-CB 3.47Å; Y451-C453 VanDerWaalsContact CE1-CB 3.47Å; Y451-C453 HydrophobicContact CE2-CB 4.48Å; Y451-C453 PolarHBondContact O-N 3.14Å; Y451-C453 VanDerWaalsContact O-N 3.1Å
454S83.5Confident90.7Very high24 Ų2442.2 Ų42.217%0.16827%0.265CS..SBendtrans-68.3145.6176.8-1740000111.6K420 S449 Y451 P452 T456 Y457K420-S454 WeakPolarHBondContact CD-O 3.45Å; K420-S454 PolarHBondContact NZ-O 3.05Å; S449-S454 VanDerWaalsContact CB-CB 3.46Å; S449-S454 VanDerWaalsContact CB-OG 3.29Å; S449-S454 WeakPolarHBondContact CB-OG 3.32Å; S449-S454 WeakPolarHBondContact OG-CB 3.26Å; Y451-S454 WeakPolarHBondContact O-CB 3.43Å; Y451-S454 PolarHBondContact O-N 3.21Å; P452-S454 VanDerWaalsContact C-N 3.34Å; S454-T456 PolarHBondContact O-N 2.81Å; S454-T456 PolarHBondContact OG-N 3.34Å; S454-T456 PolarHBondContact OG-OG1 3Å; S454-Y457 WeakPolarHBondContact O-CB 3.14Å; S454-Y457 PolarHBondContact O-N 3.3Å
455E83.4Confident91Very high58 Ų5840.5 Ų40.527%0.27125%0.247SC..THydrogen-bonded Turntrans-65.2-20.6171-70.3-53.8113.100113.2R419 D434R419-E455 WeakPolarHBondContact CB-OE2 3.46Å; D434-E455 WeakPolarHBondContact CB-O 3.27Å
456T86.6Confident91.3Very high39 Ų3938 Ų3824%0.23924%0.237CC..THydrogen-bonded Turntrans-108.824.1177.6590000112.3S449 S454 H458S449-T456 PolarHBondContact N-O 3.1Å; S454-T456 PolarHBondContact O-N 2.81Å; S454-T456 PolarHBondContact OG-N 3.34Å; S454-T456 PolarHBondContact OG-OG1 3Å; T456-H458 PolarHBondContact O-N 2.86Å
457Y93.1Very high91.8Very high21 Ų2134.3 Ų34.38%0.08221%0.212CC..BIsolated β-bridgetrans-59.5120.9178176-132.4000111N425 V433 D434 S449 S450 Y451 P452 S454 G459N425-Y457 WeakPolarHBondContact OD1-CE1 3.44Å; V433-Y457 HydrophobicContact CB-CD1 4.42Å; V433-Y457 WeakPolarHBondContact CG1-O 3.39Å; V433-Y457 HydrophobicContact CG2-CD1 3.82Å; V433-Y457 HydrophobicContact CG2-CE1 3.77Å; D434-Y457 PolarHBondContact N-O 3.33Å; S449-Y457 CarbonylContact O-C 3.58Å; S449-Y457 VanDerWaalsContact O-CA 3.27Å; S449-Y457 WeakPolarHBondContact O-CA 3.14Å; S449-Y457 WeakPolarHBondContact O-CD2 3.46Å; S450-Y457 WeakPolarHBondContact O-CE2 3.48Å; Y451-Y457 WeakPolarHBondContact O-CB 3.03Å; P452-Y457 HydrophobicContact CB-CD1 4.22Å; P452-Y457 HydrophobicContact CB-CE1 3.99Å; P452-Y457 HydrophobicContact CB-CE2 4.44Å; P452-Y457 HydrophobicContact CG-CE1 4.26Å; P452-Y457 HydrophobicContact CG-CE2 4.02Å; S454-Y457 WeakPolarHBondContact O-CB 3.14Å; S454-Y457 PolarHBondContact O-N 3.3Å; Y457-G459 VanDerWaalsContact C-N 3.29Å; Y457-G459 VanDerWaalsContact CE1-CA 3.48Å; Y457-G459 PolarHBondContact O-N 3.27Å
458H95.6Very high92.5Very high26 Ų2633 Ų3312%0.1220%0.198CC..  trans-75.9-12.2-177.351.865.4000114.4V433 R437 N438 F443 A448 S449 S450 T456V433-H458 WeakPolarHBondContact CG1-O 3.2Å; R437-H458 HydrophobicContact CB-CB 4.05Å; N438-H458 PolarHBondContact ND2-O 3.34Å; F443-H458 HydrophobicContact CE2-CB 3.99Å; F443-H458 WeakPolarHBondContact CE2-O 3.49Å; F443-H458 HydrophobicContact CZ-CB 4.23Å; F443-H458 AromaticContact CZ-ND1 3.67Å; A448-H458 HydrophobicContact CB-CB 3.88Å; S449-H458 VanDerWaalsContact C-CD2 3.42Å; S449-H458 PolarHBondContact O-CD2 3.46Å; S449-H458 PolarHBondContact O-N 3.49Å; S449-H458 PolarHBondContact O-NE2 3.33Å; S450-H458 VanDerWaalsContact CA-NE2 3.28Å; S450-H458 WeakPolarHBondContact CA-NE2 3.43Å; S450-H458 WeakPolarHBondContact CB-NE2 3.36Å; T456-H458 PolarHBondContact O-N 2.86Å
459G97.2Very high93.1Very high0 Ų036 Ų360%021%0.207CC..  trans89.6172.1-175.500000113.2Y457 S461Y457-G459 VanDerWaalsContact C-N 3.29Å; Y457-G459 VanDerWaalsContact CE1-CA 3.48Å; Y457-G459 PolarHBondContact O-N 3.27Å; G459-S461 VanDerWaalsContact C-N 3.31Å; G459-S461 PolarHBondContact O-N 2.89Å
460P96.8Very high93.7Very high93 Ų9336.4 Ų36.460%0.60421%0.21SC*.SBendtrans-71.4-23.5-17627.7-36.2000113.8
461S98.5Very high94.1Very high60 Ų6032 Ų3242%0.4218%0.18SC..SBendtrans-161.5158.6179.261.50000110N438 F443 G459 H463 S464N438-S461 PolarHBondContact ND2-O 3.23Å; N438-S461 VanDerWaalsContact ND2-O 3.11Å; F443-S461 VanDerWaalsContact CE2-C 3.49Å; F443-S461 VanDerWaalsContact CZ-CA 3.48Å; G459-S461 VanDerWaalsContact C-N 3.31Å; G459-S461 PolarHBondContact O-N 2.89Å; S461-H463 PolarHBondContact O-N 3.02Å; S461-S464 VanDerWaalsContact O-CB 3.26Å; S461-S464 WeakPolarHBondContact O-CB 3.33Å; S461-S464 PolarHBondContact O-N 3.45Å; S461-S464 PolarHBondContact O-OG 3.28Å
462A98.6Very high94.7Very high25 Ų2527.4 Ų27.421%0.20716%0.162CC..THydrogen-bonded Turntrans-58139.1172.600000111.1N438 N440 F443 S464N438-A462 CarbonylContact O-C 3.58Å; N438-A462 WeakPolarHBondContact O-CA 3.49Å; N440-A462 HydrophobicContact CB-CB 3.71Å; F443-A462 HydrophobicContact CB-CB 4.09Å; F443-A462 HydrophobicContact CD1-CB 4.3Å; F443-A462 HydrophobicContact CD2-CB 3.68Å; F443-A462 HydrophobicContact CE2-CB 4.17Å; F443-A462 HydrophobicContact CG-CB 3.75Å; F443-A462 VanDerWaalsContact CZ-N 3.28Å; A462-S464 PolarHBondContact O-N 2.8Å
463H98.4Very high95.2Very high32 Ų3230.5 Ų30.515%0.14818%0.178CC..THydrogen-bonded Turntrans5831.7-177-39140.8000113.7N438 N440 S461 E465 K469 W549N438-H463 PolarHBondContact O-N 2.64Å; N438-H463 VanDerWaalsContact OD1-CA 3.24Å; N438-H463 WeakPolarHBondContact OD1-CA 3.12Å; N438-H463 PolarHBondContact OD1-N 3.32Å; N440-H463 WeakPolarHBondContact CB-CE1 3.42Å; N440-H463 WeakPolarHBondContact CB-NE2 3.18Å; N440-H463 PolarHBondContact N-NE2 3.45Å; S461-H463 PolarHBondContact O-N 3.02Å; H463-E465 PolarHBondContact O-N 2.69Å; H463-K469 HydrophobicContact CB-CD 3.99Å; H463-W549 AromaticContact CE1-NE1 3.91Å; H463-W549 AromaticContact NE2-NE1 3.8Å
464S98.6Very high96.1Very high19 Ų1930.3 Ų30.313%0.13317%0.173CC..  trans-69.2-23.3174.765.10000113.3K423 N438 S461 A462K423-S464 PolarHBondContact NZ-O 3.48Å; N438-S464 PolarHBondContact ND2-OG 3.17Å; N438-S464 PolarHBondContact OD1-N 3.32Å; S461-S464 VanDerWaalsContact O-CB 3.26Å; S461-S464 WeakPolarHBondContact O-CB 3.33Å; S461-S464 PolarHBondContact O-N 3.45Å; S461-S464 PolarHBondContact O-OG 3.28Å; A462-S464 PolarHBondContact O-N 2.8Å
465E98.6Very high96.8Very high1 Ų129.5 Ų29.51%0.00517%0.168CC..SBendtrans-88.1129.9-178.9-55.6-47.693.300110.1T421 K423 V433 N438 H463 E467 V468 K469T421-E465 WeakPolarHBondContact CB-OE2 3.35Å; T421-E465 HydrophobicContact CG2-CB 4.22Å; T421-E465 HydrophobicContact CG2-CG 4.04Å; T421-E465 PolarHBondContact OG1-OE2 2.84Å; K423-E465 IonicContact NZ-OE1 2.81Å; V433-E465 VanDerWaalsContact CB-CD 3.42Å; V433-E465 HydrophobicContact CB-CG 3.65Å; V433-E465 HydrophobicContact CG1-CG 3.78Å; V433-E465 VanDerWaalsContact CG2-CD 3.46Å; V433-E465 HydrophobicContact CG2-CG 4.18Å; V433-E465 WeakPolarHBondContact CG2-OE1 3.37Å; N438-E465 HydrophobicContact CB-CG 4.35Å; N438-E465 PolarHBondContact OD1-N 3.45Å; N438-E465 VanDerWaalsContact OD1-N 3.11Å; H463-E465 PolarHBondContact O-N 2.69Å; E465-E467 PolarHBondContact O-N 3.38Å; E465-V468 HydrophobicContact CB-CB 4.33Å; E465-V468 HydrophobicContact CB-CG2 4.21Å; E465-V468 PolarHBondContact O-N 2.83Å; E465-K469 VanDerWaalsContact O-CB 3.29Å; E465-K469 WeakPolarHBondContact O-CB 3.26Å; E465-K469 PolarHBondContact O-N 2.76Å
466S98.4Very high97.5Very high34 Ų3432.6 Ų32.624%0.23818%0.18CC..Hα-helixtrans-56.5-39.3-178.927.40000112.4Q332 Y334 K469 S470Q332-S466 WeakPolarHBondContact O-CB 3.04Å; Y334-S466 PolarHBondContact N-OG 3.4Å; S466-K469 PolarHBondContact O-N 3.38Å; S466-S470 WeakPolarHBondContact O-CB 3.47Å; S466-S470 PolarHBondContact O-N 3.31Å; S466-S470 PolarHBondContact O-OG 3.38Å
467E98.8Very high98.1Very high2 Ų235.4 Ų35.41%0.00920%0.202CC..Hα-helixtrans-59.4-51.9178.3-62.278.9179.700110.3S333 Y334 L339 E465 I471S333-E467 WeakPolarHBondContact CA-OE1 2.95Å; S333-E467 VanDerWaalsContact CB-OE1 3.24Å; S333-E467 WeakPolarHBondContact CB-OE1 3.45Å; Y334-E467 PolarHBondContact N-OE1 3.04Å; L339-E467 HydrophobicContact CD2-CG 4.25Å; E465-E467 PolarHBondContact O-N 3.38Å; E467-I471 PolarHBondContact O-N 3.25Å
468V98.9Very high98.3Very high1 Ų135.6 Ų35.61%0.00620%0.203CC..Hα-helixtrans-67-44.8177.3173.50000110.9P435 N438 W439 E465 S470 I471 V472P435-V468 HydrophobicContact CB-CG2 4.01Å; P435-V468 WeakPolarHBondContact O-CG2 3.23Å; N438-V468 HydrophobicContact CB-CG2 4.34Å; W439-V468 HydrophobicContact CD2-CG1 3.72Å; W439-V468 HydrophobicContact CE3-CG1 4.06Å; W439-V468 HydrophobicContact CG-CG1 4.17Å; W439-V468 HydrophobicContact CH2-CG1 4.33Å; W439-V468 HydrophobicContact CZ2-CG1 3.99Å; W439-V468 HydrophobicContact CZ2-CG2 4.41Å; W439-V468 HydrophobicContact CZ3-CG1 4.35Å; E465-V468 HydrophobicContact CB-CB 4.33Å; E465-V468 HydrophobicContact CB-CG2 4.21Å; E465-V468 PolarHBondContact O-N 2.83Å; V468-S470 VanDerWaalsContact C-N 3.29Å; V468-S470 PolarHBondContact O-N 2.75Å; V468-I471 PolarHBondContact O-N 3.26Å; V468-V472 HydrophobicContact CG1-CG2 4.33Å; V468-V472 WeakPolarHBondContact O-CG2 3.3Å; V468-V472 PolarHBondContact O-N 2.82Å
469K98.8Very high98.4Very high84 Ų8437.4 Ų37.437%0.36523%0.228SC..Hα-helixtrans-60.3-38.6-178.6-176.761.6168.268.20112H463 E465 S466 V472 D473H463-K469 HydrophobicContact CB-CD 3.99Å; E465-K469 VanDerWaalsContact O-CB 3.29Å; E465-K469 WeakPolarHBondContact O-CB 3.26Å; E465-K469 PolarHBondContact O-N 2.76Å; S466-K469 PolarHBondContact O-N 3.38Å; K469-V472 PolarHBondContact O-N 3Å; K469-D473 IonicContact NZ-OD1 3.29Å; K469-D473 PolarHBondContact NZ-OD1 2.61Å; K469-D473 IonicContact NZ-OD2 2.77Å; K469-D473 PolarHBondContact NZ-OD2 3.45Å; K469-D473 WeakPolarHBondContact O-CB 3.23Å; K469-D473 VanDerWaalsContact O-CG 3.25Å; K469-D473 PolarHBondContact O-N 3.22Å
470S98.9Very high98.4Very high15 Ų1538.9 Ų38.911%0.10524%0.237CC..Hα-helixtrans-63.4-41.4176.9-810000112.8I330 G331 S466 V468 D473 F474I330-S470 PolarHBondContact O-OG 3.34Å; G331-S470 WeakPolarHBondContact CA-OG 3.38Å; S466-S470 WeakPolarHBondContact O-CB 3.47Å; S466-S470 PolarHBondContact O-N 3.31Å; S466-S470 PolarHBondContact O-OG 3.38Å; V468-S470 VanDerWaalsContact C-N 3.29Å; V468-S470 PolarHBondContact O-N 2.75Å; S470-D473 PolarHBondContact O-N 3.19Å; S470-F474 WeakPolarHBondContact O-CB 3.37Å; S470-F474 PolarHBondContact O-N 2.96Å
471I98.9Very high98.5Very high0 Ų035 Ų350%021%0.21CC..Hα-helixtrans-67.4-43.3175.2-55.9169.8000110.3I330 W355 E400 T403 W439 E467 V468 D473 F474 V475 F484I330-I471 HydrophobicContact CD1-CG1 4.06Å; W355-I471 HydrophobicContact CH2-CG1 4.33Å; W355-I471 HydrophobicContact CH2-CG2 4.21Å; W355-I471 HydrophobicContact CZ2-CB 4.47Å; W355-I471 HydrophobicContact CZ2-CD1 4.24Å; W355-I471 HydrophobicContact CZ2-CG1 3.97Å; W355-I471 HydrophobicContact CZ2-CG2 3.78Å; E400-I471 WeakPolarHBondContact OE2-CD1 3.36Å; T403-I471 HydrophobicContact CG2-CD1 3.67Å; W439-I471 HydrophobicContact CH2-CB 3.86Å; W439-I471 HydrophobicContact CH2-CD1 4.12Å; W439-I471 HydrophobicContact CH2-CG2 3.76Å; W439-I471 HydrophobicContact CZ2-CD1 4.27Å; W439-I471 HydrophobicContact CZ3-CG2 4.4Å; E467-I471 PolarHBondContact O-N 3.25Å; V468-I471 PolarHBondContact O-N 3.26Å; I471-D473 VanDerWaalsContact C-N 3.31Å; I471-D473 PolarHBondContact O-N 3.12Å; I471-F474 PolarHBondContact O-N 3.11Å; I471-V475 HydrophobicContact CG2-CG2 3.98Å; I471-V475 WeakPolarHBondContact O-CB 3.29Å; I471-V475 VanDerWaalsContact O-CG2 3.25Å; I471-V475 WeakPolarHBondContact O-CG2 3.35Å; I471-V475 PolarHBondContact O-N 3.33Å; I471-F484 HydrophobicContact CG2-CE2 3.97Å; I471-F484 HydrophobicContact CG2-CZ 4.01Å
472V98.9Very high98.5Very high2 Ų233.6 Ų33.61%0.01220%0.197CC..Hα-helixtrans-56.2-46.3176.5166.70000111.5W439 V468 K469 K476 W549W439-V472 HydrophobicContact CE3-CG2 3.85Å; W439-V472 HydrophobicContact CZ3-CG2 3.64Å; V468-V472 HydrophobicContact CG1-CG2 4.33Å; V468-V472 WeakPolarHBondContact O-CG2 3.3Å; V468-V472 PolarHBondContact O-N 2.82Å; K469-V472 PolarHBondContact O-N 3Å; V472-K476 HydrophobicContact CG1-CD 4.17Å; V472-K476 WeakPolarHBondContact O-CB 3.36Å; V472-K476 WeakPolarHBondContact O-CG 3.35Å; V472-K476 PolarHBondContact O-N 2.89Å; V472-W549 HydrophobicContact CB-CH2 4.11Å; V472-W549 HydrophobicContact CB-CZ2 4.17Å; V472-W549 HydrophobicContact CG1-CH2 4.1Å; V472-W549 HydrophobicContact CG1-CZ2 3.75Å; V472-W549 HydrophobicContact CG2-CH2 3.91Å; V472-W549 HydrophobicContact CG2-CZ2 3.87Å; V472-W549 HydrophobicContact CG2-CZ3 4.26Å
473D98.8Very high98.5Very high73 Ų7332.5 Ų32.539%0.3919%0.187SC..Hα-helixtrans-67.8-39.8179-69.8-17.3000111.6K469 S470 I471 S477K469-D473 IonicContact NZ-OD1 3.29Å; K469-D473 PolarHBondContact NZ-OD1 2.61Å; K469-D473 IonicContact NZ-OD2 2.77Å; K469-D473 PolarHBondContact NZ-OD2 3.45Å; K469-D473 WeakPolarHBondContact O-CB 3.23Å; K469-D473 VanDerWaalsContact O-CG 3.25Å; K469-D473 PolarHBondContact O-N 3.22Å; S470-D473 PolarHBondContact O-N 3.19Å; I471-D473 VanDerWaalsContact C-N 3.31Å; I471-D473 PolarHBondContact O-N 3.12Å; D473-S477 VanDerWaalsContact O-CB 3.22Å; D473-S477 WeakPolarHBondContact O-CB 3.24Å; D473-S477 PolarHBondContact O-N 2.9Å; D473-S477 PolarHBondContact O-OG 2.77Å
474F98.8Very high98.6Very high27 Ų2731 Ų3112%0.11818%0.18CC..Hα-helixtrans-62.4-50.7175.2-177.6-91000111.7I330 W355 F398 S470 I471 K476 S477 H478 I481I330-F474 HydrophobicContact CB-CD2 4.45Å; I330-F474 HydrophobicContact CG2-CB 4.39Å; I330-F474 HydrophobicContact CG2-CD2 3.54Å; I330-F474 HydrophobicContact CG2-CE2 4.09Å; I330-F474 HydrophobicContact CG2-CG 4.11Å; W355-F474 AromaticContact CE3-CD1 3.82Å; W355-F474 HydrophobicContact CE3-CD1 3.82Å; W355-F474 AromaticContact CE3-CE1 3.74Å; W355-F474 HydrophobicContact CE3-CE1 3.74Å; W355-F474 HydrophobicContact CH2-CD1 4.33Å; W355-F474 AromaticContact CZ3-CD1 3.37Å; W355-F474 HydrophobicContact CZ3-CD1 3.37Å; W355-F474 AromaticContact CZ3-CE1 3.52Å; W355-F474 HydrophobicContact CZ3-CE1 3.52Å; W355-F474 HydrophobicContact CZ3-CG 4.11Å; W355-F474 HydrophobicContact CZ3-CZ 4.35Å; F398-F474 HydrophobicContact CD1-CE1 4.3Å; F398-F474 AromaticContact CD1-CZ 3.73Å; F398-F474 HydrophobicContact CD1-CZ 3.73Å; F398-F474 HydrophobicContact CD2-CE1 4.22Å; F398-F474 HydrophobicContact CD2-CZ 4.24Å; F398-F474 HydrophobicContact CE1-CE1 4.44Å; F398-F474 HydrophobicContact CE1-CE2 4.38Å; F398-F474 AromaticContact CE1-CZ 3.56Å; F398-F474 HydrophobicContact CE1-CZ 3.56Å; F398-F474 HydrophobicContact CE2-CE1 4.36Å; F398-F474 HydrophobicContact CE2-CZ 4.1Å; F398-F474 HydrophobicContact CG-CE1 4.19Å; F398-F474 HydrophobicContact CG-CZ 4.07Å; F398-F474 HydrophobicContact CZ-CE1 4.47Å; F398-F474 AromaticContact CZ-CZ 3.77Å; F398-F474 HydrophobicContact CZ-CZ 3.77Å; S470-F474 WeakPolarHBondContact O-CB 3.37Å; S470-F474 PolarHBondContact O-N 2.96Å; I471-F474 PolarHBondContact O-N 3.11Å; F474-K476 VanDerWaalsContact C-N 3.34Å; F474-K476 PolarHBondContact O-N 3.22Å; F474-S477 WeakPolarHBondContact CA-OG 3.33Å; F474-S477 PolarHBondContact O-N 3.36Å; F474-S477 PolarHBondContact O-OG 3.48Å; F474-H478 HydrophobicContact CE1-CB 4.39Å; F474-H478 VanDerWaalsContact O-CB 3.3Å; F474-H478 WeakPolarHBondContact O-CB 3.45Å; F474-H478 PolarHBondContact O-N 3.11Å; F474-I481 HydrophobicContact CD1-CD1 4.28Å; F474-I481 HydrophobicContact CE1-CD1 4.12Å
475V98.6Very high98.6Very high8 Ų830 Ų305%0.04817%0.174CC..Hα-helixtrans-59.4-46.4-179.2168.50000110.8I471 G479 I481 F484 W549 I555I471-V475 HydrophobicContact CG2-CG2 3.98Å; I471-V475 WeakPolarHBondContact O-CB 3.29Å; I471-V475 VanDerWaalsContact O-CG2 3.25Å; I471-V475 WeakPolarHBondContact O-CG2 3.35Å; I471-V475 PolarHBondContact O-N 3.33Å; V475-G479 PolarHBondContact O-N 3.28Å; V475-I481 HydrophobicContact CB-CD1 4.22Å; V475-I481 HydrophobicContact CG1-CD1 4.36Å; V475-I481 HydrophobicContact CG2-CD1 3.81Å; V475-F484 HydrophobicContact CG2-CD2 4.33Å; V475-F484 HydrophobicContact CG2-CE2 3.89Å; V475-W549 HydrophobicContact CB-CH2 4Å; V475-W549 HydrophobicContact CB-CZ3 4.14Å; V475-W549 HydrophobicContact CG1-CH2 3.88Å; V475-W549 HydrophobicContact CG1-CZ3 3.96Å; V475-W549 HydrophobicContact CG2-CZ3 4.29Å; V475-I555 HydrophobicContact CG1-CD1 3.72Å
476K98.4Very high98.6Very high122 Ų12230 Ų3053%0.5317%0.174SC..Hα-helixtrans-66.8-40.2178.8-75.5-179.8171.5176.90113V472 F474V472-K476 HydrophobicContact CG1-CD 4.17Å; V472-K476 WeakPolarHBondContact O-CB 3.36Å; V472-K476 WeakPolarHBondContact O-CG 3.35Å; V472-K476 PolarHBondContact O-N 2.89Å; F474-K476 VanDerWaalsContact C-N 3.34Å; F474-K476 PolarHBondContact O-N 3.22Å
477S98.1Very high98.6Very high99 Ų9928.4 Ų28.469%0.69216%0.163SC*.Hα-helixtrans-73.1-35.9179.959.90000112.6D473 F474D473-S477 VanDerWaalsContact O-CB 3.22Å; D473-S477 WeakPolarHBondContact O-CB 3.24Å; D473-S477 PolarHBondContact O-N 2.9Å; D473-S477 PolarHBondContact O-OG 2.77Å; F474-S477 WeakPolarHBondContact CA-OG 3.33Å; F474-S477 PolarHBondContact O-N 3.36Å; F474-S477 PolarHBondContact O-OG 3.48Å
478H97.9Very high98.6Very high25 Ų2528.3 Ų28.312%0.11616%0.162CC..Hα-helixtrans-67.6-48.7173.9-170.3-82.6000111.1N350 R351 F398 F474 N480 I481N350-H478 PolarHBondContact OD1-O 3.46Å; R351-H478 PolarHBondContact O-CE1 3.21Å; F398-H478 AromaticContact CE2-CD2 3.85Å; F398-H478 AromaticContact CE2-NE2 3.56Å; F398-H478 AromaticContact CZ-CD2 3.92Å; F398-H478 AromaticContact CZ-NE2 3.83Å; F474-H478 HydrophobicContact CE1-CB 4.39Å; F474-H478 VanDerWaalsContact O-CB 3.3Å; F474-H478 WeakPolarHBondContact O-CB 3.45Å; F474-H478 PolarHBondContact O-N 3.11Å; H478-N480 PolarHBondContact ND1-N 3.11Å; H478-N480 PolarHBondContact O-N 2.81Å; H478-I481 HydrophobicContact CB-CD1 4.41Å; H478-I481 HydrophobicContact CB-CG1 4.4Å
479G97.2Very high98.3Very high63 Ų6328.3 Ų28.365%0.64916%0.163SC*.  trans68.4-7.2173.300000116.3V475V475-G479 PolarHBondContact O-N 3.28Å
480N98Very high98.2Very high32 Ų3224.7 Ų24.717%0.17115%0.147CC..  trans-123.628.8-178.6-153.413.5000114.3N350 P352 A353 H478 K482N350-N480 PolarHBondContact O-ND2 3.26Å; N350-N480 WeakPolarHBondContact OD1-CB 3.24Å; P352-N480 CarbonylContact C-O 3.52Å; P352-N480 WeakPolarHBondContact CA-O 3.45Å; A353-N480 PolarHBondContact N-O 3.47Å; H478-N480 PolarHBondContact ND1-N 3.11Å; H478-N480 PolarHBondContact O-N 2.81Å; N480-K482 WeakPolarHBondContact OD1-CE 3.34Å; N480-K482 PolarHBondContact OD1-NZ 3.26Å
481I98.6Very high97.9Very high11 Ų1124.5 Ų24.56%0.05615%0.146CC..EExtended strand (participates in β ladder)trans-79.2129.2172.7-61172.7000108.8A353 W355 F474 V475 H478 A483 I555A353-I481 HydrophobicContact CB-CG1 4.26Å; A353-I481 CarbonylContact O-C 3.6Å; A353-I481 WeakPolarHBondContact O-CA 3.17Å; W355-I481 HydrophobicContact CB-CG2 4.06Å; F474-I481 HydrophobicContact CD1-CD1 4.28Å; F474-I481 HydrophobicContact CE1-CD1 4.12Å; V475-I481 HydrophobicContact CB-CD1 4.22Å; V475-I481 HydrophobicContact CG1-CD1 4.36Å; V475-I481 HydrophobicContact CG2-CD1 3.81Å; H478-I481 HydrophobicContact CB-CD1 4.41Å; H478-I481 HydrophobicContact CB-CG1 4.4Å; I481-A483 VanDerWaalsContact CG2-O 3.23Å; I481-A483 WeakPolarHBondContact CG2-O 3.25Å; I481-I555 HydrophobicContact CB-CD1 4.03Å; I481-I555 HydrophobicContact CG2-CD1 3.94Å; I481-I555 HydrophobicContact CG2-CG2 4.28Å
482K98.6Very high97.8Very high31 Ų3125.8 Ų25.814%0.13515%0.151CC..EExtended strand (participates in β ladder)trans-105.6-31.4-174.9-58.3-54-177.8-1750113.5P352 A353 M395 N480 I555 T596 Y601P352-K482 HydrophobicContact CB-CG 3.81Å; A353-K482 PolarHBondContact O-N 3.46Å; M395-K482 HydrophobicContact CE-CB 4Å; M395-K482 HydrophobicContact CE-CG 4.09Å; N480-K482 WeakPolarHBondContact OD1-CE 3.34Å; N480-K482 PolarHBondContact OD1-NZ 3.26Å; K482-I555 WeakPolarHBondContact O-CG2 3.22Å; K482-T596 HydrophobicContact CB-CG2 3.64Å; K482-Y601 WeakPolarHBondContact CD-O 3.33Å; K482-Y601 WeakPolarHBondContact CE-O 3.46Å; K482-Y601 PolarHBondContact NZ-O 2.97Å; K482-Y601 PolarHBondContact O-OH 3.29Å
483A98.9Very high97.7Very high1 Ų126 Ų261%0.00815%0.153CC..EExtended strand (participates in β ladder)trans-131.4145.5172.600000110.7I354 W355 I481 Y557 T596I354-A483 HydrophobicContact CG1-CB 4.17Å; I354-A483 HydrophobicContact CG2-CB 4.29Å; W355-A483 PolarHBondContact N-O 2.99Å; I481-A483 VanDerWaalsContact CG2-O 3.23Å; I481-A483 WeakPolarHBondContact CG2-O 3.25Å; A483-Y557 CarbonylContact C-O 3.55Å; A483-Y557 VanDerWaalsContact CA-O 3.23Å; A483-Y557 WeakPolarHBondContact CA-O 3.4Å; A483-T596 HydrophobicContact CB-CG2 3.95Å
484F98.9Very high97.7Very high0 Ų022.6 Ų22.60%013%0.134CC..EExtended strand (participates in β ladder)trans-134.6119177.5-165.4-67.3000109W355 D357 I471 V475 T546 T550 I555 Y557 S558 Y559W355-F484 HydrophobicContact CB-CD2 3.76Å; W355-F484 HydrophobicContact CB-CE2 4.16Å; W355-F484 HydrophobicContact CB-CG 4.21Å; W355-F484 AromaticContact CD1-CD1 3.79Å; W355-F484 AromaticContact CD1-CD2 3.5Å; W355-F484 AromaticContact CD1-CE1 3.48Å; W355-F484 VanDerWaalsContact CD1-CE1 3.48Å; W355-F484 AromaticContact CD1-CE2 3.2Å; W355-F484 AromaticContact CD1-CG 3.79Å; W355-F484 AromaticContact CD1-CZ 3.19Å; W355-F484 HydrophobicContact CD2-CE2 4.01Å; W355-F484 HydrophobicContact CD2-CZ 4.44Å; W355-F484 AromaticContact CE2-CE2 3.99Å; W355-F484 AromaticContact CE2-CZ 4Å; W355-F484 AromaticContact CG-CD2 3.65Å; W355-F484 HydrophobicContact CG-CD2 3.65Å; W355-F484 HydrophobicContact CG-CE1 4.5Å; W355-F484 AromaticContact CG-CE2 3.53Å; W355-F484 HydrophobicContact CG-CE2 3.53Å; W355-F484 HydrophobicContact CG-CG 4.22Å; W355-F484 AromaticContact CG-CZ 3.99Å; W355-F484 HydrophobicContact CG-CZ 3.99Å; W355-F484 AromaticContact NE1-CE1 3.71Å; W355-F484 AromaticContact NE1-CE2 3.49Å; W355-F484 AromaticContact NE1-CZ 3.17Å; W355-F484 WeakPolarHBondContact O-CA 3.36Å; D357-F484 WeakPolarHBondContact OD2-CE1 3.04Å; D357-F484 WeakPolarHBondContact OD2-CZ 3.2Å; I471-F484 HydrophobicContact CG2-CE2 3.97Å; I471-F484 HydrophobicContact CG2-CZ 4.01Å; V475-F484 HydrophobicContact CG2-CD2 4.33Å; V475-F484 HydrophobicContact CG2-CE2 3.89Å; F484-T546 HydrophobicContact CD1-CG2 4.15Å; F484-T546 HydrophobicContact CE1-CG2 3.29Å; F484-T546 HydrophobicContact CZ-CG2 3.67Å; F484-T550 HydrophobicContact CB-CG2 4.11Å; F484-T550 HydrophobicContact CD1-CG2 3.88Å; F484-T550 HydrophobicContact CD2-CG2 3.41Å; F484-T550 VanDerWaalsContact CD2-CG2 3.41Å; F484-T550 HydrophobicContact CE1-CG2 4.13Å; F484-T550 HydrophobicContact CE2-CG2 3.66Å; F484-T550 HydrophobicContact CG-CG2 3.53Å; F484-T550 HydrophobicContact CZ-CG2 4.01Å; F484-I555 HydrophobicContact CB-CG2 4.06Å; F484-I555 HydrophobicContact CD2-CD1 4.41Å; F484-Y557 PolarHBondContact N-O 3.32Å; F484-S558 CarbonylContact O-C 3.42Å; F484-S558 WeakPolarHBondContact O-CA 3.47Å; F484-Y559 PolarHBondContact O-N 3.23Å
485I98.9Very high97.7Very high0 Ų021.4 Ų21.40%013%0.129CC..EExtended strand (participates in β ladder)trans-123.7109-174.4-59141.5000109.2I354 W355 I356 D357 I487 Y559 F561 L589 L592I354-I485 HydrophobicContact CG2-CD1 4.08Å; W355-I485 PolarHBondContact O-N 3.44Å; I356-I485 VanDerWaalsContact CA-O 3.31Å; I356-I485 WeakPolarHBondContact CA-O 3.08Å; I356-I485 HydrophobicContact CG1-CB 4.43Å; I356-I485 HydrophobicContact CG1-CD1 4.2Å; D357-I485 PolarHBondContact N-O 3.23Å; I485-I487 HydrophobicContact CG2-CD1 4.43Å; I485-I487 HydrophobicContact CG2-CG1 4Å; I485-Y559 VanDerWaalsContact CA-O 3.3Å; I485-Y559 WeakPolarHBondContact CA-O 3.35Å; I485-F561 HydrophobicContact CG2-CD2 3.75Å; I485-F561 HydrophobicContact CG2-CE2 3.84Å; I485-L589 HydrophobicContact CD1-CD2 4.11Å; I485-L589 HydrophobicContact CG2-CD2 3.77Å; I485-L592 HydrophobicContact CD1-CB 4.49Å; I485-L592 HydrophobicContact CD1-CD1 4.28Å; I485-L592 HydrophobicContact CG1-CD1 4.14Å
486S98.9Very high97.7Very high0 Ų021.3 Ų21.30%013%0.128CC..EExtended strand (participates in β ladder)trans-103.4119.4178.4-171.80000110.5D357 Y559 T560 F561D357-S486 WeakPolarHBondContact OD1-CA 3.48Å; D357-S486 WeakPolarHBondContact OD1-CB 3.39Å; D357-S486 PolarHBondContact OD1-OG 3.41Å; S486-Y559 PolarHBondContact N-O 3.43Å; S486-T560 WeakPolarHBondContact O-CA 3.45Å; S486-T560 WeakPolarHBondContact O-CB 3.27Å; S486-T560 PolarHBondContact O-OG1 3.09Å; S486-F561 PolarHBondContact O-N 3.14Å; S486-F561 VanDerWaalsContact O-N 3.1Å
487I98.9Very high97.7Very high0 Ų015.5 Ų15.50%010%0.102CC..EExtended strand (participates in β ladder)trans-106.9123.1-167.6-55.4179.1000110.7I356 D357 T358 T367 F374 I485 F561 L563 L589I356-I487 HydrophobicContact CG2-CD1 3.73Å; I356-I487 HydrophobicContact CG2-CG1 4.39Å; D357-I487 WeakPolarHBondContact O-CB 3.49Å; D357-I487 PolarHBondContact O-N 3.18Å; T358-I487 HydrophobicContact CG2-CB 3.94Å; T358-I487 HydrophobicContact CG2-CD1 4.05Å; T358-I487 HydrophobicContact CG2-CG1 4.42Å; T358-I487 HydrophobicContact CG2-CG2 4.36Å; T367-I487 HydrophobicContact CG2-CG2 4.15Å; T367-I487 WeakPolarHBondContact CG2-O 3.11Å; F374-I487 HydrophobicContact CE2-CD1 3.85Å; I485-I487 HydrophobicContact CG2-CD1 4.43Å; I485-I487 HydrophobicContact CG2-CG1 4Å; I487-F561 HydrophobicContact CG1-CB 4.44Å; I487-F561 HydrophobicContact CG1-CD2 4.4Å; I487-F561 HydrophobicContact CG2-CB 4.13Å; I487-L563 HydrophobicContact CG2-CD1 3.61Å; I487-L563 HydrophobicContact CG2-CD2 4.08Å; I487-L563 HydrophobicContact CG2-CG 3.75Å; I487-L589 HydrophobicContact CD1-CD1 4.43Å; I487-L589 HydrophobicContact CD1-CD2 4.42Å
488H98.8Very high97.7Very high0 Ų012.4 Ų12.40%08%0.076CC..EExtended strand (participates in β ladder)trans-118.7171.8179.9-70.7-84000112.6I360 H361 E364 N436 T560 F561 E562 L563I360-H488 WeakPolarHBondContact CG2-CE1 3.29Å; H361-H488 AromaticContact CE1-CE1 3.18Å; H361-H488 PolarHBondContact CE1-CE1 3.04Å; H361-H488 AromaticContact CE1-ND1 3.52Å; H361-H488 AromaticContact ND1-CE1 3.25Å; H361-H488 PolarHBondContact ND1-CE1 2.96Å; H361-H488 VanDerWaalsContact ND1-CE1 3.25Å; H361-H488 AromaticContact ND1-ND1 3.13Å; H361-H488 PolarHBondContact ND1-ND1 2.92Å; H361-H488 VanDerWaalsContact ND1-ND1 3.13Å; E364-H488 IonicContact OE1-ND1 3.44Å; E364-H488 WeakPolarHBondContact OE2-CA 3.44Å; E364-H488 VanDerWaalsContact OE2-CB 3.24Å; E364-H488 WeakPolarHBondContact OE2-CB 3.42Å; E364-H488 IonicContact OE2-CG 2.76Å; E364-H488 IonicContact OE2-ND1 3.57Å; E364-H488 PolarHBondContact OE2-ND1 3.29Å; N436-H488 PolarHBondContact ND2-NE2 3.42Å; N436-H488 VanDerWaalsContact ND2-NE2 3.1Å; H488-T560 PolarHBondContact CD2-OG1 3.3Å; H488-F561 CarbonylContact C-O 3.01Å; H488-F561 VanDerWaalsContact CA-O 3.31Å; H488-F561 WeakPolarHBondContact CA-O 3.28Å; H488-F561 VanDerWaalsContact CB-O 3.23Å; H488-F561 WeakPolarHBondContact CB-O 3.38Å; H488-F561 PolarHBondContact N-O 3.45Å; H488-E562 VanDerWaalsContact CB-OE2 3.25Å; H488-E562 WeakPolarHBondContact CB-OE2 3.31Å; H488-E562 CarbonylContact O-C 3.54Å; H488-E562 WeakPolarHBondContact O-CA 3.31Å; H488-L563 VanDerWaalsContact O-CG 3.31Å; H488-L563 WeakPolarHBondContact O-CG 3.35Å; H488-L563 PolarHBondContact O-N 3.29Å
489A92.8Very high97.6Very high2 Ų211.2 Ų11.22%0.0177%0.07CC..EExtended strand (participates in β ladder)trans-143.4150.5162.300000109.7E364 V366 T367 E562 L563 F571E364-A489 HydrophobicContact CB-CB 4.21Å; E364-A489 WeakPolarHBondContact CG-O 3.37Å; E364-A489 PolarHBondContact OE2-N 3.37Å; V366-A489 HydrophobicContact CG1-CB 3.44Å; V366-A489 VanDerWaalsContact CG1-CB 3.44Å; T367-A489 HydrophobicContact CG2-CB 4.08Å; A489-E562 WeakPolarHBondContact CA-OE2 3.21Å; A489-E562 PolarHBondContact N-OE2 3.26Å; A489-L563 HydrophobicContact CB-CB 4.15Å; A489-F571 VanDerWaalsContact O-CE1 3.23Å; A489-F571 WeakPolarHBondContact O-CE1 3.31Å
490Y96.2Very high97.5Very high7 Ų710.5 Ų10.53%0.0275%0.048CC..SBendcis-125.6162.95.964.7-81.5000109.2W233 M234 D244 E562 L563 G567 G570 F571W233-Y490 HydrophobicContact CB-CE1 4.13Å; W233-Y490 VanDerWaalsContact CB-OH 3.3Å; W233-Y490 WeakPolarHBondContact CB-OH 3.32Å; W233-Y490 HydrophobicContact CE3-CE1 4.22Å; M234-Y490 HydrophobicContact CE-CD2 4.23Å; M234-Y490 HydrophobicContact CE-CE2 3.54Å; D244-Y490 WeakPolarHBondContact CB-OH 3.42Å; D244-Y490 PolarHBondContact OD2-OH 3.19Å; D244-Y490 VanDerWaalsContact OD2-OH 3.1Å; Y490-E562 PolarHBondContact N-OE2 3.33Å; Y490-L563 WeakPolarHBondContact CA-O 3.38Å; Y490-G567 VanDerWaalsContact CE2-CA 3.45Å; Y490-G570 VanDerWaalsContact CD1-CA 3.41Å; Y490-F571 AromaticContact CD1-CD1 3.69Å; Y490-F571 HydrophobicContact CD1-CD1 3.69Å; Y490-F571 AromaticContact CD1-CE1 3.53Å; Y490-F571 HydrophobicContact CD1-CE1 3.53Å; Y490-F571 HydrophobicContact CD1-CG 4.26Å; Y490-F571 AromaticContact CD1-CZ 3.96Å; Y490-F571 HydrophobicContact CD1-CZ 3.96Å; Y490-F571 HydrophobicContact CE1-CD1 4.1Å; Y490-F571 HydrophobicContact CE1-CD2 4.31Å; Y490-F571 AromaticContact CE1-CE1 3.73Å; Y490-F571 HydrophobicContact CE1-CE1 3.73Å; Y490-F571 AromaticContact CE1-CE2 3.97Å; Y490-F571 HydrophobicContact CE1-CE2 3.97Å; Y490-F571 HydrophobicContact CE1-CG 4.36Å; Y490-F571 AromaticContact CE1-CZ 3.65Å; Y490-F571 HydrophobicContact CE1-CZ 3.65Å
491S91.6Very high97.4Very high12 Ų1210.5 Ų10.58%0.0845%0.05CC..SBendtrans164.6-7.5161-83.50000112.7M234 L563 D565M234-S491 VanDerWaalsContact CE-OG 3.32Å; M234-S491 WeakPolarHBondContact CE-OG 3.45Å; S491-L563 PolarHBondContact N-O 2.81Å; S491-D565 CarbonylContact C-O 3.5Å; S491-D565 WeakPolarHBondContact CA-O 3.43Å; S491-D565 PolarHBondContact N-O 3.35Å; S491-D565 VanDerWaalsContact N-O 3.13Å
492Q97.4Very high97.3Very high26 Ų2615.2 Ų15.212%0.1218%0.079CC..  trans57.365.9-170.7-61.6175.3-170.600111.9T528 R529 Y530 R531 E562 L563 R564 T566Q492-T528 HydrophobicContact CG-CG2 4.27Å; Q492-R529 WeakPolarHBondContact CB-O 3.13Å; Q492-R529 PolarHBondContact NE2-O 3.45Å; Q492-Y530 HydrophobicContact CB-CD1 4.24Å; Q492-Y530 HydrophobicContact CB-CD2 3.64Å; Q492-Y530 HydrophobicContact CB-CE1 4.28Å; Q492-Y530 HydrophobicContact CB-CE2 3.67Å; Q492-Y530 HydrophobicContact CB-CG 3.91Å; Q492-Y530 HydrophobicContact CG-CD2 4.12Å; Q492-Y530 HydrophobicContact CG-CE2 3.68Å; Q492-Y530 CarbonylContact O-C 3.47Å; Q492-Y530 WeakPolarHBondContact O-CA 3.44Å; Q492-R531 PolarHBondContact O-N 3.01Å; Q492-E562 CarbonylContact C-O 3.58Å; Q492-E562 WeakPolarHBondContact CA-O 3.44Å; Q492-E562 PolarHBondContact N-O 3.31Å; Q492-L563 PolarHBondContact N-O 3.32Å; Q492-R564 HydrophobicContact CG-CG 4.43Å; Q492-T566 HydrophobicContact CB-CG2 4.23Å; Q492-T566 HydrophobicContact CG-CG2 4.1Å
493M97.3Very high97.2Very high8 Ų817.9 Ų17.94%0.03910%0.098CC..EExtended strand (participates in β ladder)trans-131.4145.5178.6-51.4-178.2178.900111.6M495 Y530 R531 V538 I539 F561 E562M493-M495 HydrophobicContact CB-CE 4.09Å; M493-M495 HydrophobicContact CB-CG 4.14Å; M493-M495 HydrophobicContact CB-SD 4.2Å; M493-M495 HydrophobicContact SD-CE 4.43Å; M493-M495 HydrophobicContact SD-SD 4.1Å; M493-Y530 VanDerWaalsContact N-CD1 3.3Å; M493-R531 CarbonylContact C-O 3.51Å; M493-R531 VanDerWaalsContact CA-O 3.25Å; M493-R531 WeakPolarHBondContact CA-O 3.43Å; M493-R531 HydrophobicContact CG-CB 4.42Å; M493-V538 HydrophobicContact CB-CG1 4.2Å; M493-V538 HydrophobicContact CG-CG1 4.09Å; M493-V538 HydrophobicContact SD-CG1 3.65Å; M493-I539 HydrophobicContact CE-CG1 4.24Å; M493-I539 HydrophobicContact SD-CB 4.02Å; M493-I539 HydrophobicContact SD-CD1 4.25Å; M493-I539 HydrophobicContact SD-CG1 3.97Å; M493-F561 CarbonylContact O-C 3.59Å; M493-F561 WeakPolarHBondContact O-CA 3.41Å; M493-E562 HydrophobicContact CB-CB 3.96Å; M493-E562 HydrophobicContact CB-CG 4.25Å; M493-E562 HydrophobicContact CG-CB 4.33Å; M493-E562 PolarHBondContact N-O 3.5Å; M493-E562 PolarHBondContact O-N 3.23Å
494L98.8Very high97.1Very high0 Ų021.6 Ų21.60%012%0.122CC..EExtended strand (participates in β ladder)trans-123.4110.3166.1172.858.9000108.9A515 A518 I519 R531 Y532 G533 Y559 F561L494-A515 HydrophobicContact CD2-CB 4.07Å; L494-A515 HydrophobicContact CG-CB 4.27Å; L494-A518 HydrophobicContact CD2-CB 3.7Å; L494-I519 HydrophobicContact CB-CD1 3.51Å; L494-I519 HydrophobicContact CB-CG1 3.85Å; L494-I519 HydrophobicContact CD2-CD1 3.83Å; L494-I519 HydrophobicContact CD2-CG1 3.97Å; L494-I519 HydrophobicContact CG-CD1 4.32Å; L494-R531 PolarHBondContact N-O 3.17Å; L494-Y532 WeakPolarHBondContact O-CA 3.41Å; L494-Y532 WeakPolarHBondContact O-CB 3.1Å; L494-G533 PolarHBondContact O-N 2.9Å; L494-Y559 HydrophobicContact CD1-CD1 3.89Å; L494-Y559 HydrophobicContact CD1-CG 4.29Å; L494-Y559 HydrophobicContact CG-CD1 4.29Å; L494-F561 HydrophobicContact CB-CD1 4.5Å; L494-F561 HydrophobicContact CB-CE1 4.35Å; L494-F561 HydrophobicContact CD1-CD1 4.14Å; L494-F561 HydrophobicContact CD1-CD2 3.79Å; L494-F561 HydrophobicContact CD1-CE1 3.9Å; L494-F561 HydrophobicContact CD1-CE2 3.53Å; L494-F561 HydrophobicContact CD1-CG 4.09Å; L494-F561 HydrophobicContact CD1-CZ 3.59Å; L494-F561 HydrophobicContact CD2-CE1 4.29Å; L494-F561 HydrophobicContact CD2-CZ 4.08Å; L494-F561 HydrophobicContact CG-CE1 4.41Å; L494-F561 HydrophobicContact CG-CZ 4.35Å
495M98.7Very high97.1Very high3 Ų321.9 Ų21.92%0.01512%0.124CC..EExtended strand (participates in β ladder)trans-118.3154.6-170.6-58.4171.5-72.700111.7M493 G533 I535 V538 I539 Y559 T560 E562M493-M495 HydrophobicContact CB-CE 4.09Å; M493-M495 HydrophobicContact CB-CG 4.14Å; M493-M495 HydrophobicContact CB-SD 4.2Å; M493-M495 HydrophobicContact SD-CE 4.43Å; M493-M495 HydrophobicContact SD-SD 4.1Å; M495-G533 CarbonylContact C-O 3.33Å; M495-G533 WeakPolarHBondContact CA-O 3.41Å; M495-I535 HydrophobicContact CB-CG1 3.71Å; M495-I535 HydrophobicContact SD-CG1 4.36Å; M495-V538 HydrophobicContact CG-CB 3.94Å; M495-V538 HydrophobicContact CG-CG1 3.92Å; M495-V538 HydrophobicContact CG-CG2 4.35Å; M495-V538 HydrophobicContact SD-CB 3.98Å; M495-V538 HydrophobicContact SD-CG1 3.97Å; M495-I539 HydrophobicContact CE-CG2 4.4Å; M495-I539 HydrophobicContact SD-CB 3.84Å; M495-I539 HydrophobicContact SD-CG2 3.77Å; M495-Y559 CarbonylContact O-C 3.59Å; M495-Y559 VanDerWaalsContact O-CA 3.31Å; M495-Y559 WeakPolarHBondContact O-CA 3.35Å; M495-Y559 WeakPolarHBondContact O-CD1 3.22Å; M495-T560 HydrophobicContact CB-CG2 3.76Å; M495-T560 HydrophobicContact CE-CG2 3.89Å; M495-T560 PolarHBondContact N-O 3.35Å; M495-T560 PolarHBondContact O-N 2.55Å; M495-E562 HydrophobicContact CE-CG 3.62Å
496Y98.8Very high97.1Very high5 Ų530.5 Ų30.52%0.0216%0.161CC..EExtended strand (participates in β ladder)trans-128170171.455.9-95.7000109.7V505 Q508 L511 H512 A515 G533 S534 I535 Y559Y496-V505 HydrophobicContact CD2-CG2 4.09Å; Y496-V505 HydrophobicContact CE2-CG2 4.15Å; Y496-Q508 HydrophobicContact CE2-CG 4.11Å; Y496-L511 HydrophobicContact CD1-CB 4.23Å; Y496-L511 HydrophobicContact CD2-CB 4.07Å; Y496-L511 HydrophobicContact CD2-CD1 4.29Å; Y496-L511 HydrophobicContact CG-CB 3.96Å; Y496-H512 HydrophobicContact CE1-CB 4.03Å; Y496-H512 AromaticContact CE1-ND1 3.81Å; Y496-H512 AromaticContact CZ-ND1 3.76Å; Y496-H512 PolarHBondContact OH-ND1 3.23Å; Y496-A515 HydrophobicContact CD1-CB 4.35Å; Y496-G533 WeakPolarHBondContact CD1-O 3.39Å; Y496-G533 VanDerWaalsContact CE1-CA 3.44Å; Y496-G533 WeakPolarHBondContact CE1-O 3.26Å; Y496-G533 VanDerWaalsContact CZ-C 3.45Å; Y496-G533 PolarHBondContact N-O 2.98Å; Y496-S534 CarbonylContact O-C 3.52Å; Y496-S534 WeakPolarHBondContact O-CA 3.24Å; Y496-I535 PolarHBondContact O-N 3.33Å; Y496-Y559 HydrophobicContact CD1-CE1 4.08Å; Y496-Y559 HydrophobicContact CG-CE1 4.36Å
497P98.8Very high97Very high0 Ų031.9 Ų31.90%017%0.169CC..SBendtrans-61.5158180-28.438.3000114.2V505 V547 D548 Y551 S558P497-V505 HydrophobicContact CB-CG1 3.7Å; P497-V505 VanDerWaalsContact O-CG1 3.28Å; P497-V505 WeakPolarHBondContact O-CG1 3.39Å; P497-V547 HydrophobicContact CG-CB 4.21Å; P497-V547 HydrophobicContact CG-CG2 4.2Å; P497-V547 WeakPolarHBondContact CG-O 3.4Å; P497-D548 WeakPolarHBondContact CB-OD1 3.46Å; P497-Y551 HydrophobicContact CB-CG 4.34Å; P497-Y551 HydrophobicContact CG-CG 4.14Å; P497-S558 VanDerWaalsContact CD-O 3.22Å; P497-S558 WeakPolarHBondContact CD-O 3.47Å
498Y98.4Very high97Very high34 Ų3435.5 Ų35.513%0.13319%0.186CC..  cis-98.7154.1-0.4-68.6-76.6000113.2Y500 T501 T503 V505 I536 D548 Y551 E552Y498-Y500 HydrophobicContact CD1-CD1 4.05Å; Y498-Y500 AromaticContact CD1-CE1 3.52Å; Y498-Y500 HydrophobicContact CD1-CE1 3.52Å; Y498-Y500 AromaticContact CE1-CE1 3.91Å; Y498-Y500 HydrophobicContact CE1-CE1 3.91Å; Y498-Y500 HydrophobicContact CG-CE1 4.26Å; Y498-T501 HydrophobicContact CD2-CG2 4.01Å; Y498-T501 HydrophobicContact CG-CG2 3.83Å; Y498-T503 WeakPolarHBondContact CD2-O 3.43Å; Y498-V505 HydrophobicContact CD2-CG1 3.55Å; Y498-V505 HydrophobicContact CE2-CB 4.28Å; Y498-V505 HydrophobicContact CE2-CG1 3.42Å; Y498-V505 VanDerWaalsContact CE2-CG1 3.42Å; Y498-V505 HydrophobicContact CG-CG1 4.24Å; Y498-I536 WeakPolarHBondContact O-CG2 3.49Å; Y498-I536 PolarHBondContact O-N 3.34Å; Y498-I536 VanDerWaalsContact O-N 3.1Å; Y498-D548 WeakPolarHBondContact CA-OD1 3.34Å; Y498-D548 HydrophobicContact CD1-CB 4.14Å; Y498-Y551 HydrophobicContact CE1-CD1 4.11Å; Y498-Y551 HydrophobicContact CE2-CE1 4.38Å; Y498-Y551 AromaticContact CZ-CD1 3.77Å; Y498-Y551 AromaticContact CZ-CE1 3.97Å; Y498-Y551 WeakPolarHBondContact OH-CD1 3.48Å; Y498-Y551 WeakPolarHBondContact OH-CE1 3.44Å; Y498-E552 HydrophobicContact CE1-CG 3.98Å
499G94.6Very high97Very high0 Ų039.5 Ų39.50%022%0.218CC..SBendtrans-93.6-39.616500000113.2Q541 A542 D548G499-Q541 WeakPolarHBondContact O-CA 3.43Å; G499-A542 CarbonylContact C-O 3.6Å; G499-A542 PolarHBondContact O-N 2.95Å; G499-D548 WeakPolarHBondContact CA-OD2 3.45Å; G499-D548 VanDerWaalsContact N-CG 3.32Å; G499-D548 PolarHBondContact N-OD1 2.89Å; G499-D548 PolarHBondContact N-OD2 2.82Å
500Y95.9Very high97.3Very high48 Ų4842.1 Ų42.119%0.18823%0.231CC..SBendtrans-81.5-17.5-17177.7-94.5000114.6A441 L445 Y498 Q541 A542 D548 E552A441-Y500 HydrophobicContact CB-CE1 4.48Å; L445-Y500 HydrophobicContact CD1-CD2 4.05Å; Y498-Y500 HydrophobicContact CD1-CD1 4.05Å; Y498-Y500 AromaticContact CD1-CE1 3.52Å; Y498-Y500 HydrophobicContact CD1-CE1 3.52Å; Y498-Y500 AromaticContact CE1-CE1 3.91Å; Y498-Y500 HydrophobicContact CE1-CE1 3.91Å; Y498-Y500 HydrophobicContact CG-CE1 4.26Å; Y500-Q541 PolarHBondContact O-NE2 3.37Å; Y500-A542 VanDerWaalsContact CA-O 3.31Å; Y500-A542 WeakPolarHBondContact CA-O 3.2Å; Y500-A542 PolarHBondContact N-O 3.43Å; Y500-D548 HydrophobicContact CD1-CB 4.11Å; Y500-D548 WeakPolarHBondContact CD1-OD2 3.38Å; Y500-D548 HydrophobicContact CE1-CB 4.39Å; Y500-D548 PolarHBondContact N-OD2 2.97Å; Y500-E552 VanDerWaalsContact CE1-OE1 3.23Å; Y500-E552 WeakPolarHBondContact CE1-OE1 3.47Å; Y500-E552 VanDerWaalsContact CZ-OE1 3.31Å; Y500-E552 PolarHBondContact OH-OE1 3.12Å
501T96.4Very high97.4Very high32 Ų3241.8 Ų41.820%0.19623%0.229CC..  trans-140150.4-174-1770000112.3Y498 T503Y498-T501 HydrophobicContact CD2-CG2 4.01Å; Y498-T501 HydrophobicContact CG-CG2 3.83Å; T501-T503 VanDerWaalsContact C-N 3.27Å; T501-T503 PolarHBondContact OG1-N 3.36Å
502T95.1Very high97.7Very high110 Ų11044.3 Ų44.368%0.67524%0.24SC*.SBendtrans-79.1-11174.655.30000112.9P504 I536T502-P504 VanDerWaalsContact O-CD 3.3Å; T502-P504 WeakPolarHBondContact O-CD 3.42Å; T502-I536 HydrophobicContact CG2-CD1 3.63Å
503T97.3Very high97.8Very high87 Ų8745.6 Ų45.653%0.53425%0.254SS..SBendtrans-64.3123.7176.2-60.60000109.6Y498 T501Y498-T503 WeakPolarHBondContact CD2-O 3.43Å; T501-T503 VanDerWaalsContact C-N 3.27Å; T501-T503 PolarHBondContact OG1-N 3.36Å
504P97.5Very high97.9Very high80 Ų8045.5 Ų45.552%0.51925%0.254SS..PPolyproline II helixtrans-58146.3174.3-32.541.2000114.4T502 Q508T502-P504 VanDerWaalsContact O-CD 3.3Å; T502-P504 WeakPolarHBondContact O-CD 3.42Å; P504-Q508 VanDerWaalsContact CB-OE1 3.23Å
505V98Very high97.9Very high5 Ų545.5 Ų45.53%0.0325%0.254CS..PPolyproline II helixtrans-60.7143.1162.2-75.60000111.2Y496 P497 Y498 D507 Q508 L511 Y551Y496-V505 HydrophobicContact CD2-CG2 4.09Å; Y496-V505 HydrophobicContact CE2-CG2 4.15Å; P497-V505 HydrophobicContact CB-CG1 3.7Å; P497-V505 VanDerWaalsContact O-CG1 3.28Å; P497-V505 WeakPolarHBondContact O-CG1 3.39Å; Y498-V505 HydrophobicContact CD2-CG1 3.55Å; Y498-V505 HydrophobicContact CE2-CB 4.28Å; Y498-V505 HydrophobicContact CE2-CG1 3.42Å; Y498-V505 VanDerWaalsContact CE2-CG1 3.42Å; Y498-V505 HydrophobicContact CG-CG1 4.24Å; V505-D507 PolarHBondContact O-N 3.04Å; V505-D507 VanDerWaalsContact O-N 3.14Å; V505-Q508 HydrophobicContact CG2-CB 3.86Å; V505-Q508 HydrophobicContact CG2-CG 4.38Å; V505-Q508 WeakPolarHBondContact O-CB 3.4Å; V505-Q508 PolarHBondContact O-N 2.91Å; V505-Q508 VanDerWaalsContact O-N 3.13Å; V505-L511 HydrophobicContact CG2-CD1 4.02Å; V505-Y551 HydrophobicContact CB-CE1 3.88Å; V505-Y551 HydrophobicContact CB-CE2 4.35Å; V505-Y551 WeakPolarHBondContact CB-OH 3.32Å; V505-Y551 HydrophobicContact CG1-CD1 3.89Å; V505-Y551 HydrophobicContact CG1-CE1 3.49Å; V505-Y551 VanDerWaalsContact CG1-CE1 3.49Å; V505-Y551 HydrophobicContact CG1-CE2 4.23Å; V505-Y551 HydrophobicContact CG1-CG 4.42Å
506K98.1Very high97.9Very high181 Ų18149.8 Ų49.879%0.78727%0.274SS*.THydrogen-bonded Turntrans-54.5-32.9175.962168.5-166.5-169.10113.2Y551K506-Y551 WeakPolarHBondContact CG-OH 3.44Å; K506-Y551 PolarHBondContact N-OH 3.32Å
507D98.3Very high97.9Very high29 Ų2954 Ų5416%0.15529%0.293CS..THydrogen-bonded Turntrans-96.318.9-176.3-63.3-70000113.3V505 A509 E510 L511 Y551 K556V505-D507 PolarHBondContact O-N 3.04Å; V505-D507 VanDerWaalsContact O-N 3.14Å; D507-A509 VanDerWaalsContact C-N 3.3Å; D507-A509 PolarHBondContact O-N 3.17Å; D507-A509 VanDerWaalsContact O-N 3.14Å; D507-E510 PolarHBondContact O-N 2.81Å; D507-E510 VanDerWaalsContact O-N 3.1Å; D507-L511 HydrophobicContact CB-CD1 4.19Å; D507-L511 HydrophobicContact CB-CG 4.16Å; D507-L511 PolarHBondContact O-N 2.95Å; D507-Y551 PolarHBondContact N-OH 2.92Å; D507-Y551 PolarHBondContact OD2-OH 3.1Å; D507-Y551 VanDerWaalsContact OD2-OH 3.05Å; D507-K556 HydrophobicContact CB-CD 4.21Å; D507-K556 HydrophobicContact CB-CG 4.37Å; D507-K556 WeakPolarHBondContact OD1-CE 3.38Å; D507-K556 IonicContact OD1-NZ 3.46Å; D507-K556 PolarHBondContact OD1-NZ 3.47Å
508Q98.4Very high97.9Very high77 Ų7754 Ų5436%0.3629%0.293SS..Hα-helixtrans-51-45.4-170.3-169.8-165.5-69.800113.5Y496 P504 V505 E510 L511 H512Y496-Q508 HydrophobicContact CE2-CG 4.11Å; P504-Q508 VanDerWaalsContact CB-OE1 3.23Å; V505-Q508 HydrophobicContact CG2-CB 3.86Å; V505-Q508 HydrophobicContact CG2-CG 4.38Å; V505-Q508 WeakPolarHBondContact O-CB 3.4Å; V505-Q508 PolarHBondContact O-N 2.91Å; V505-Q508 VanDerWaalsContact O-N 3.13Å; Q508-E510 VanDerWaalsContact C-N 3.33Å; Q508-E510 PolarHBondContact O-N 3.36Å; Q508-L511 PolarHBondContact O-N 2.82Å; Q508-H512 WeakPolarHBondContact O-CB 3.14Å; Q508-H512 PolarHBondContact O-N 3.37Å
509A98.6Very high97.9Very high83 Ų8353 Ų5369%0.68629%0.289SS*.Hα-helixtrans-60.8-43.3-176.400000112.1D507 A513D507-A509 VanDerWaalsContact C-N 3.3Å; D507-A509 PolarHBondContact O-N 3.17Å; D507-A509 VanDerWaalsContact O-N 3.14Å; A509-A513 WeakPolarHBondContact O-CB 3.47Å; A509-A513 PolarHBondContact O-N 3.27Å; A509-A513 VanDerWaalsContact O-N 3.13Å
510E98.6Very high98.1Very high58 Ų5857.1 Ų57.127%0.27132%0.315SS..Hα-helixtrans-71.4-46178.4-173.6178.3161.600111.1D507 Q508 H512 A513 L514 K556 Y557 H595D507-E510 PolarHBondContact O-N 2.81Å; D507-E510 VanDerWaalsContact O-N 3.1Å; Q508-E510 VanDerWaalsContact C-N 3.33Å; Q508-E510 PolarHBondContact O-N 3.36Å; E510-H512 VanDerWaalsContact C-N 3.28Å; E510-H512 PolarHBondContact O-N 3.12Å; E510-A513 PolarHBondContact O-N 2.96Å; E510-L514 WeakPolarHBondContact O-CB 3.43Å; E510-L514 PolarHBondContact O-N 3.46Å; E510-K556 IonicContact OE1-NZ 3.09Å; E510-K556 WeakPolarHBondContact OE2-CE 3.06Å; E510-K556 IonicContact OE2-NZ 3.49Å; E510-K556 PolarHBondContact OE2-NZ 3.23Å; E510-Y557 VanDerWaalsContact OE1-CE1 3.3Å; E510-Y557 WeakPolarHBondContact OE1-CE1 3.41Å; E510-Y557 PolarHBondContact OE1-OH 2.99Å; E510-H595 IonicContact OE1-CD2 3.65Å; E510-H595 IonicContact OE1-CE1 3.33Å; E510-H595 IonicContact OE1-NE2 2.75Å; E510-H595 PolarHBondContact OE1-NE2 3.31Å
511L98.8Very high98.2Very high0 Ų057.2 Ų57.20%032%0.318CS..Hα-helixtrans-63.1-37.7-178.8-65.7177.9000112.2Y496 V505 D507 Q508 A515 Y551 K556 Y557 Y559Y496-L511 HydrophobicContact CD1-CB 4.23Å; Y496-L511 HydrophobicContact CD2-CB 4.07Å; Y496-L511 HydrophobicContact CD2-CD1 4.29Å; Y496-L511 HydrophobicContact CG-CB 3.96Å; V505-L511 HydrophobicContact CG2-CD1 4.02Å; D507-L511 HydrophobicContact CB-CD1 4.19Å; D507-L511 HydrophobicContact CB-CG 4.16Å; D507-L511 PolarHBondContact O-N 2.95Å; Q508-L511 PolarHBondContact O-N 2.82Å; L511-A515 WeakPolarHBondContact O-CB 2.94Å; L511-A515 PolarHBondContact O-N 2.84Å; L511-Y551 HydrophobicContact CD1-CD2 4.4Å; L511-Y551 HydrophobicContact CD1-CE2 3.87Å; L511-K556 WeakPolarHBondContact CD2-O 3.43Å; L511-Y557 HydrophobicContact CD2-CD1 3.85Å; L511-Y557 HydrophobicContact CD2-CE1 4.47Å; L511-Y559 WeakPolarHBondContact CA-OH 3.39Å; L511-Y559 HydrophobicContact CD2-CE2 4Å; L511-Y559 WeakPolarHBondContact CD2-OH 3.5Å; L511-Y559 PolarHBondContact O-OH 3.41Å
512H98.8Very high98.3Very high65 Ų6555.7 Ų55.730%0.30131%0.309SS..Hα-helixtrans-69.2-45.2177.4-165.987.8000112.4Y496 Q508 E510 L514 A515 Q516 Y532Y496-H512 HydrophobicContact CE1-CB 4.03Å; Y496-H512 AromaticContact CE1-ND1 3.81Å; Y496-H512 AromaticContact CZ-ND1 3.76Å; Y496-H512 PolarHBondContact OH-ND1 3.23Å; Q508-H512 WeakPolarHBondContact O-CB 3.14Å; Q508-H512 PolarHBondContact O-N 3.37Å; E510-H512 VanDerWaalsContact C-N 3.28Å; E510-H512 PolarHBondContact O-N 3.12Å; H512-L514 VanDerWaalsContact C-N 3.32Å; H512-L514 PolarHBondContact O-N 3Å; H512-A515 PolarHBondContact O-N 3.33Å; H512-Q516 PolarHBondContact O-N 3.19Å; H512-Y532 AromaticContact CE1-CD2 3.89Å; H512-Y532 AromaticContact CE1-CE2 3.75Å; H512-Y532 AromaticContact NE2-CE2 3.5Å
513A98.8Very high98.5Very high52 Ų5252 Ų5243%0.4329%0.29SS..Hα-helixtrans-63.1-39.8177.400000111.7A509 E510 Q516 K517A509-A513 WeakPolarHBondContact O-CB 3.47Å; A509-A513 PolarHBondContact O-N 3.27Å; A509-A513 VanDerWaalsContact O-N 3.13Å; E510-A513 PolarHBondContact O-N 2.96Å; A513-Q516 PolarHBondContact O-N 2.93Å; A513-K517 PolarHBondContact O-N 3.38Å
514L98.8Very high98.5Very high6 Ų652.1 Ų52.13%0.03129%0.294CS..Hα-helixtrans-67.9-40.8176.1178.258.8000111.9E510 H512 Q516 K517 A518 Y557 Y559 L592 H595E510-L514 WeakPolarHBondContact O-CB 3.43Å; E510-L514 PolarHBondContact O-N 3.46Å; H512-L514 VanDerWaalsContact C-N 3.32Å; H512-L514 PolarHBondContact O-N 3Å; L514-Q516 VanDerWaalsContact C-N 3.34Å; L514-Q516 PolarHBondContact O-N 3.2Å; L514-K517 PolarHBondContact O-N 2.95Å; L514-A518 WeakPolarHBondContact O-CB 3.32Å; L514-A518 PolarHBondContact O-N 3.22Å; L514-Y557 HydrophobicContact CD2-CD1 4.01Å; L514-Y557 HydrophobicContact CD2-CE1 4.23Å; L514-Y559 WeakPolarHBondContact CB-OH 3.46Å; L514-Y559 HydrophobicContact CD2-CE2 4.05Å; L514-L592 HydrophobicContact CD1-CD2 4.07Å; L514-L592 HydrophobicContact CD2-CD2 3.83Å; L514-L592 HydrophobicContact CG-CD2 3.59Å; L514-H595 HydrophobicContact CD1-CB 3.56Å; L514-H595 HydrophobicContact CD2-CB 3.91Å; L514-H595 HydrophobicContact CG-CB 4.4Å
515A98.8Very high98.6Very high0 Ų051.9 Ų51.90%029%0.288CS..Hα-helixtrans-60.4-43.8173.700000111.8L494 Y496 L511 H512 K517 A518 I519 Y532 Y559L494-A515 HydrophobicContact CD2-CB 4.07Å; L494-A515 HydrophobicContact CG-CB 4.27Å; Y496-A515 HydrophobicContact CD1-CB 4.35Å; L511-A515 WeakPolarHBondContact O-CB 2.94Å; L511-A515 PolarHBondContact O-N 2.84Å; H512-A515 PolarHBondContact O-N 3.33Å; A515-K517 VanDerWaalsContact C-N 3.34Å; A515-K517 PolarHBondContact O-N 3.05Å; A515-A518 PolarHBondContact O-N 3.23Å; A515-I519 WeakPolarHBondContact O-CG1 3.28Å; A515-I519 PolarHBondContact O-N 3.28Å; A515-Y532 HydrophobicContact CB-CD2 4.18Å; A515-Y532 HydrophobicContact CB-CG 4.37Å; A515-Y559 HydrophobicContact CB-CE1 4.04Å
516Q98.8Very high98.5Very high93 Ų9356.9 Ų56.944%0.43531%0.307SS..Hα-helixtrans-58.9-45.2175.6179.4175.132.200111.7H512 A513 L514 T520 Y532H512-Q516 PolarHBondContact O-N 3.19Å; A513-Q516 PolarHBondContact O-N 2.93Å; L514-Q516 VanDerWaalsContact C-N 3.34Å; L514-Q516 PolarHBondContact O-N 3.2Å; Q516-T520 WeakPolarHBondContact O-CB 3.47Å; Q516-T520 PolarHBondContact O-N 3.16Å; Q516-T520 PolarHBondContact O-OG1 3.15Å; Q516-Y532 HydrophobicContact CB-CD2 4.39Å; Q516-Y532 HydrophobicContact CB-CE1 4.41Å; Q516-Y532 HydrophobicContact CB-CE2 3.68Å; Q516-Y532 HydrophobicContact CG-CE1 4.45Å; Q516-Y532 HydrophobicContact CG-CE2 4.26Å; Q516-Y532 WeakPolarHBondContact CG-OH 3.2Å; Q516-Y532 PolarHBondContact NE2-OH 3.48Å
517K98.8Very high98.5Very high95 Ų9550.6 Ų50.641%0.41329%0.294SS..Hα-helixtrans-61-50.5176.2-175.7-172.2179.6-61.80111A513 L514 A515 I519 T520 D521A513-K517 PolarHBondContact O-N 3.38Å; L514-K517 PolarHBondContact O-N 2.95Å; A515-K517 VanDerWaalsContact C-N 3.34Å; A515-K517 PolarHBondContact O-N 3.05Å; K517-I519 VanDerWaalsContact C-N 3.31Å; K517-I519 PolarHBondContact O-N 2.83Å; K517-T520 WeakPolarHBondContact O-CB 3.28Å; K517-T520 PolarHBondContact O-N 3.12Å; K517-T520 VanDerWaalsContact O-N 3.09Å; K517-D521 IonicContact NZ-OD2 3.77Å; K517-D521 PolarHBondContact NZ-OD2 3.39Å; K517-D521 PolarHBondContact O-N 2.94Å
518A98.8Very high98.5Very high0 Ų049.9 Ų49.90%029%0.29CS..Hα-helixtrans-58.7-42-178.500000112.1L494 L514 A515 D521 L522 A588 A591 L592L494-A518 HydrophobicContact CD2-CB 3.7Å; L514-A518 WeakPolarHBondContact O-CB 3.32Å; L514-A518 PolarHBondContact O-N 3.22Å; A515-A518 PolarHBondContact O-N 3.23Å; A518-D521 PolarHBondContact O-N 3.15Å; A518-L522 WeakPolarHBondContact O-CB 3.28Å; A518-L522 PolarHBondContact O-N 2.88Å; A518-A588 HydrophobicContact CB-CB 3.99Å; A518-A588 WeakPolarHBondContact O-CB 3.48Å; A518-A591 HydrophobicContact CB-CB 4.12Å; A518-L592 HydrophobicContact CB-CD2 4Å; A518-L592 HydrophobicContact CB-CG 4.3Å
519I98.6Very high98.4Very high11 Ų1156.5 Ų56.56%0.05631%0.312CS..Hα-helixtrans-70.4-34.1175.4-67.5-43000112.8L494 A515 K517 D521 L522 A523 Y530 Y532L494-I519 HydrophobicContact CB-CD1 3.51Å; L494-I519 HydrophobicContact CB-CG1 3.85Å; L494-I519 HydrophobicContact CD2-CD1 3.83Å; L494-I519 HydrophobicContact CD2-CG1 3.97Å; L494-I519 HydrophobicContact CG-CD1 4.32Å; A515-I519 WeakPolarHBondContact O-CG1 3.28Å; A515-I519 PolarHBondContact O-N 3.28Å; K517-I519 VanDerWaalsContact C-N 3.31Å; K517-I519 PolarHBondContact O-N 2.83Å; I519-D521 VanDerWaalsContact C-N 3.33Å; I519-L522 HydrophobicContact CD1-CD1 4.29Å; I519-L522 PolarHBondContact O-N 3.15Å; I519-A523 VanDerWaalsContact O-CB 3.31Å; I519-A523 WeakPolarHBondContact O-CB 3.39Å; I519-A523 PolarHBondContact O-N 3.16Å; I519-Y530 VanDerWaalsContact CD1-CB 3.41Å; I519-Y530 HydrophobicContact CD1-CD1 3.73Å; I519-Y530 HydrophobicContact CD1-CG 3.74Å; I519-Y532 HydrophobicContact CB-CD1 4.15Å; I519-Y532 HydrophobicContact CG1-CD1 4.06Å; I519-Y532 HydrophobicContact CG1-CG 4.47Å; I519-Y532 HydrophobicContact CG2-CD1 4.24Å
520T98.8Very high98.4Very high88 Ų8853.3 Ų53.354%0.5428%0.282SS..Hα-helixtrans-62.6-43.6173.6-58.30000110.7Q516 K517 A523 S524Q516-T520 WeakPolarHBondContact O-CB 3.47Å; Q516-T520 PolarHBondContact O-N 3.16Å; Q516-T520 PolarHBondContact O-OG1 3.15Å; K517-T520 WeakPolarHBondContact O-CB 3.28Å; K517-T520 PolarHBondContact O-N 3.12Å; K517-T520 VanDerWaalsContact O-N 3.09Å; T520-A523 PolarHBondContact O-N 3.33Å; T520-S524 PolarHBondContact O-N 3.42Å
521D98.6Very high98.3Very high50 Ų5054.7 Ų54.727%0.26729%0.285SS..Hα-helixtrans-66.7-42.9178-65.6-13.2000111.1K517 A518 I519 S524 L587 A591K517-D521 IonicContact NZ-OD2 3.77Å; K517-D521 PolarHBondContact NZ-OD2 3.39Å; K517-D521 PolarHBondContact O-N 2.94Å; A518-D521 PolarHBondContact O-N 3.15Å; I519-D521 VanDerWaalsContact C-N 3.33Å; D521-S524 WeakPolarHBondContact O-CB 3.45Å; D521-S524 PolarHBondContact O-N 3.34Å; D521-S524 PolarHBondContact O-OG 3.47Å; D521-L587 HydrophobicContact CB-CB 4.31Å; D521-L587 VanDerWaalsContact O-CD1 3.3Å; D521-L587 WeakPolarHBondContact O-CD1 3.47Å; D521-A591 WeakPolarHBondContact OD2-CB 3.15Å
522L98.6Very high98.2Very high0 Ų058 Ų580%030%0.298CS..Hα-helixtrans-57.1-51.1173.6-175.5157.1000112A518 I519 S524 L525 Y530 F561 E584 A588A518-L522 WeakPolarHBondContact O-CB 3.28Å; A518-L522 PolarHBondContact O-N 2.88Å; I519-L522 HydrophobicContact CD1-CD1 4.29Å; I519-L522 PolarHBondContact O-N 3.15Å; L522-S524 PolarHBondContact O-N 2.93Å; L522-S524 VanDerWaalsContact O-N 3.13Å; L522-L525 PolarHBondContact O-N 2.94Å; L522-Y530 HydrophobicContact CD1-CD1 4.34Å; L522-Y530 HydrophobicContact CD1-CD2 4.16Å; L522-Y530 HydrophobicContact CD1-CE1 4.09Å; L522-Y530 HydrophobicContact CD1-CE2 3.91Å; L522-Y530 HydrophobicContact CD1-CG 4.4Å; L522-Y530 HydrophobicContact CD2-CD2 3.7Å; L522-Y530 HydrophobicContact CD2-CE2 3.66Å; L522-Y530 HydrophobicContact CG-CE2 4.48Å; L522-F561 HydrophobicContact CD1-CE1 4.48Å; L522-E584 HydrophobicContact CD1-CG 4.38Å; L522-E584 HydrophobicContact CD2-CB 4.12Å; L522-E584 HydrophobicContact CD2-CG 3.93Å; L522-E584 HydrophobicContact CG-CB 3.89Å; L522-E584 HydrophobicContact CG-CG 3.88Å; L522-E584 WeakPolarHBondContact CG-O 3.31Å; L522-A588 HydrophobicContact CB-CB 4.14Å; L522-A588 HydrophobicContact CD1-CB 4.15Å
523A98.4Very high98.2Very high32 Ų3255.2 Ų55.226%0.26429%0.286SS..Hα-helixtrans-64-20.3-177.400000112.8I519 T520 L525 G527 T528I519-A523 VanDerWaalsContact O-CB 3.31Å; I519-A523 WeakPolarHBondContact O-CB 3.39Å; I519-A523 PolarHBondContact O-N 3.16Å; T520-A523 PolarHBondContact O-N 3.33Å; A523-L525 PolarHBondContact O-N 2.91Å; A523-G527 WeakPolarHBondContact O-CA 3.4Å; A523-G527 PolarHBondContact O-N 3.44Å; A523-T528 WeakPolarHBondContact CB-O 3.49Å
524S98.6Very high98.1Very high90 Ų9053.2 Ų53.263%0.62927%0.27SS*.Hα-helixtrans-64.4-24.5-179.777.40000113.9T520 D521 L522T520-S524 PolarHBondContact O-N 3.42Å; D521-S524 WeakPolarHBondContact O-CB 3.45Å; D521-S524 PolarHBondContact O-N 3.34Å; D521-S524 PolarHBondContact O-OG 3.47Å; L522-S524 PolarHBondContact O-N 2.93Å; L522-S524 VanDerWaalsContact O-N 3.13Å
525L97.8Very high98Very high75 Ų7553.5 Ų53.539%0.39327%0.271SS..Hα-helixtrans-84.3-52.4-175.5-168.362.3000112.5L522 A523 E583 E584 L587L522-L525 PolarHBondContact O-N 2.94Å; A523-L525 PolarHBondContact O-N 2.91Å; L525-E583 HydrophobicContact CD2-CB 3.61Å; L525-E584 HydrophobicContact CB-CB 4.4Å; L525-E584 HydrophobicContact CD2-CB 4.26Å; L525-L587 HydrophobicContact CB-CD1 3.87Å; L525-L587 HydrophobicContact CD2-CD1 4.38Å
526Y97.8Very high97.6Very high110 Ų11054.7 Ų54.743%0.43128%0.277SS..Hα-helixtrans-1241.9-173.8-63.1-53.6000114.4T528 P580 E583 E584Y526-T528 PolarHBondContact O-N 2.81Å; Y526-P580 HydrophobicContact CD2-CB 4.18Å; Y526-P580 HydrophobicContact CE2-CB 3.78Å; Y526-P580 VanDerWaalsContact CE2-O 3.31Å; Y526-P580 WeakPolarHBondContact CE2-O 3.22Å; Y526-E583 HydrophobicContact CE2-CB 4.31Å; Y526-E583 PolarHBondContact OH-OE2 2.83Å; Y526-E584 HydrophobicContact CD2-CB 4.05Å
527G98Very high97.1Very high49 Ų4955.8 Ų55.851%0.50529%0.286SS..  trans72.99.7-176.100000114.1A523 R529A523-G527 WeakPolarHBondContact O-CA 3.4Å; A523-G527 PolarHBondContact O-N 3.44Å; G527-R529 PolarHBondContact O-N 3.31Å
528T97.4Very high96.6Very high14 Ų1451.7 Ų51.79%0.08627%0.269CS..  trans-64.3125.5-179-46.70000110.2Q492 A523 Y526 Y530 R564 E584Q492-T528 HydrophobicContact CG-CG2 4.27Å; A523-T528 WeakPolarHBondContact CB-O 3.49Å; Y526-T528 PolarHBondContact O-N 2.81Å; T528-Y530 HydrophobicContact CG2-CD2 4.1Å; T528-Y530 HydrophobicContact CG2-CE2 3.68Å; T528-R564 HydrophobicContact CG2-CG 4.38Å; T528-R564 PolarHBondContact OG1-NH2 3.04Å; T528-E584 VanDerWaalsContact CB-OE2 3.22Å; T528-E584 WeakPolarHBondContact CB-OE2 3.31Å; T528-E584 PolarHBondContact OG1-OE1 3.43Å; T528-E584 PolarHBondContact OG1-OE2 3.17Å
529R96.9Very high95.8Very high216 Ų21652.4 Ų52.482%0.81527%0.272SS*.  trans-97.3120.6-173.6-63-174.7179.4-173.8-0.7110.4Q492 G527Q492-R529 WeakPolarHBondContact CB-O 3.13Å; Q492-R529 PolarHBondContact NE2-O 3.45Å; G527-R529 PolarHBondContact O-N 3.31Å
530Y97.9Very high94.9Very high15 Ų1554.4 Ų54.46%0.05928%0.28CS..  trans-107.8145.9173.8-81.5-129.1000111Q492 M493 I519 L522 T528 F561 E562 L563Q492-Y530 HydrophobicContact CB-CD1 4.24Å; Q492-Y530 HydrophobicContact CB-CD2 3.64Å; Q492-Y530 HydrophobicContact CB-CE1 4.28Å; Q492-Y530 HydrophobicContact CB-CE2 3.67Å; Q492-Y530 HydrophobicContact CB-CG 3.91Å; Q492-Y530 HydrophobicContact CG-CD2 4.12Å; Q492-Y530 HydrophobicContact CG-CE2 3.68Å; Q492-Y530 CarbonylContact O-C 3.47Å; Q492-Y530 WeakPolarHBondContact O-CA 3.44Å; M493-Y530 VanDerWaalsContact N-CD1 3.3Å; I519-Y530 VanDerWaalsContact CD1-CB 3.41Å; I519-Y530 HydrophobicContact CD1-CD1 3.73Å; I519-Y530 HydrophobicContact CD1-CG 3.74Å; L522-Y530 HydrophobicContact CD1-CD1 4.34Å; L522-Y530 HydrophobicContact CD1-CD2 4.16Å; L522-Y530 HydrophobicContact CD1-CE1 4.09Å; L522-Y530 HydrophobicContact CD1-CE2 3.91Å; L522-Y530 HydrophobicContact CD1-CG 4.4Å; L522-Y530 HydrophobicContact CD2-CD2 3.7Å; L522-Y530 HydrophobicContact CD2-CE2 3.66Å; L522-Y530 HydrophobicContact CG-CE2 4.48Å; T528-Y530 HydrophobicContact CG2-CD2 4.1Å; T528-Y530 HydrophobicContact CG2-CE2 3.68Å; Y530-F561 HydrophobicContact CE1-CD1 4.25Å; Y530-E562 VanDerWaalsContact CE1-O 3.25Å; Y530-E562 WeakPolarHBondContact CE1-O 3.5Å; Y530-L563 WeakPolarHBondContact OH-CA 3.02Å
531R95.6Very high94.4Very high87 Ų8754.1 Ų54.133%0.32827%0.272SS..EExtended strand (participates in β ladder)trans-85.2152.7163.4-65.9174.765.3-146.4-4.1109.4Q492 M493 L494 V538Q492-R531 PolarHBondContact O-N 3.01Å; M493-R531 CarbonylContact C-O 3.51Å; M493-R531 VanDerWaalsContact CA-O 3.25Å; M493-R531 WeakPolarHBondContact CA-O 3.43Å; M493-R531 HydrophobicContact CG-CB 4.42Å; L494-R531 PolarHBondContact N-O 3.17Å; R531-V538 HydrophobicContact CB-CG1 3.97Å; R531-V538 PolarHBondContact NH1-O 3.18Å; R531-V538 PolarHBondContact NH2-O 3.48Å
532Y98.2Very high93.8Very high71 Ų7151.9 Ų51.928%0.27826%0.261SS..EExtended strand (participates in β ladder)trans-147.9156.1176.660.3-92.1000112.6L494 H512 A515 Q516 I519 V538L494-Y532 WeakPolarHBondContact O-CA 3.41Å; L494-Y532 WeakPolarHBondContact O-CB 3.1Å; H512-Y532 AromaticContact CE1-CD2 3.89Å; H512-Y532 AromaticContact CE1-CE2 3.75Å; H512-Y532 AromaticContact NE2-CE2 3.5Å; A515-Y532 HydrophobicContact CB-CD2 4.18Å; A515-Y532 HydrophobicContact CB-CG 4.37Å; Q516-Y532 HydrophobicContact CB-CD2 4.39Å; Q516-Y532 HydrophobicContact CB-CE1 4.41Å; Q516-Y532 HydrophobicContact CB-CE2 3.68Å; Q516-Y532 HydrophobicContact CG-CE1 4.45Å; Q516-Y532 HydrophobicContact CG-CE2 4.26Å; Q516-Y532 WeakPolarHBondContact CG-OH 3.2Å; Q516-Y532 PolarHBondContact NE2-OH 3.48Å; I519-Y532 HydrophobicContact CB-CD1 4.15Å; I519-Y532 HydrophobicContact CG1-CD1 4.06Å; I519-Y532 HydrophobicContact CG1-CG 4.47Å; I519-Y532 HydrophobicContact CG2-CD1 4.24Å; Y532-V538 VanDerWaalsContact C-CG2 3.48Å
533G98Very high93.6Very high5 Ų551.9 Ų51.95%0.05226%0.261CS..EExtended strand (participates in β ladder)trans148.6-169.5-172.700000112.5L494 M495 Y496L494-G533 PolarHBondContact O-N 2.9Å; M495-G533 CarbonylContact C-O 3.33Å; M495-G533 WeakPolarHBondContact CA-O 3.41Å; Y496-G533 WeakPolarHBondContact CD1-O 3.39Å; Y496-G533 VanDerWaalsContact CE1-CA 3.44Å; Y496-G533 WeakPolarHBondContact CE1-O 3.26Å; Y496-G533 VanDerWaalsContact CZ-C 3.45Å; Y496-G533 PolarHBondContact N-O 2.98Å
534S97.9Very high93.5Very high11 Ų1150.4 Ų50.48%0.07725%0.248CC..EExtended strand (participates in β ladder)trans-71.4147.1173.160.40000110.9Y496 I536 N537 V538Y496-S534 CarbonylContact O-C 3.52Å; Y496-S534 WeakPolarHBondContact O-CA 3.24Å; S534-I536 VanDerWaalsContact C-N 3.31Å; S534-I536 PolarHBondContact O-N 2.85Å; S534-N537 PolarHBondContact O-N 3.28Å; S534-N537 PolarHBondContact OG-ND2 3.13Å; S534-V538 WeakPolarHBondContact O-CG2 3.43Å; S534-V538 PolarHBondContact O-N 3.36Å
535I95Very high93.5Very high11 Ų1146.2 Ų46.26%0.05622%0.219CC..Hα-helixtrans-48-53.4-178.2-68166.3000111M495 Y496 N537 V538 I539 Y540 A542 V547 T560M495-I535 HydrophobicContact CB-CG1 3.71Å; M495-I535 HydrophobicContact SD-CG1 4.36Å; Y496-I535 PolarHBondContact O-N 3.33Å; I535-N537 PolarHBondContact O-N 3.42Å; I535-N537 VanDerWaalsContact O-N 3.12Å; I535-V538 PolarHBondContact O-N 3.19Å; I535-I539 HydrophobicContact CG2-CG2 3.73Å; I535-I539 WeakPolarHBondContact O-CG2 3.48Å; I535-I539 PolarHBondContact O-N 3.42Å; I535-Y540 PolarHBondContact O-N 2.9Å; I535-A542 HydrophobicContact CG2-CB 4.48Å; I535-V547 HydrophobicContact CD1-CG2 3.42Å; I535-V547 VanDerWaalsContact CD1-CG2 3.42Å; I535-T560 HydrophobicContact CD1-CG2 4.08Å; I535-T560 HydrophobicContact CG1-CG2 4.11Å
536I91.8Very high93.5Very high26 Ų2642.7 Ų42.713%0.13320%0.201CC..Hα-helixtrans-59-30.1-176.3-166.7163.2000114.2Y498 T502 S534 Q541Y498-I536 WeakPolarHBondContact O-CG2 3.49Å; Y498-I536 PolarHBondContact O-N 3.34Å; Y498-I536 VanDerWaalsContact O-N 3.1Å; T502-I536 HydrophobicContact CG2-CD1 3.63Å; S534-I536 VanDerWaalsContact C-N 3.31Å; S534-I536 PolarHBondContact O-N 2.85Å; I536-Q541 HydrophobicContact CD1-CB 3.91Å; I536-Q541 HydrophobicContact CD1-CG 3.93Å; I536-Q541 HydrophobicContact CG1-CB 4.02Å
537N88.6Confident93.6Very high116 Ų11637.6 Ų37.662%0.6218%0.181SC*.Hα-helixtrans-92.4-24.9-176.7-72-39.1000112.9S534 I535S534-N537 PolarHBondContact O-N 3.28Å; S534-N537 PolarHBondContact OG-ND2 3.13Å; I535-N537 PolarHBondContact O-N 3.42Å; I535-N537 VanDerWaalsContact O-N 3.12Å
538V87.3Confident93.6Very high8 Ų835.3 Ų35.35%0.04816%0.157CC..Hα-helixtrans-92-46.8-178178.20000110.8M493 M495 R531 Y532 S534 I535M493-V538 HydrophobicContact CB-CG1 4.2Å; M493-V538 HydrophobicContact CG-CG1 4.09Å; M493-V538 HydrophobicContact SD-CG1 3.65Å; M495-V538 HydrophobicContact CG-CB 3.94Å; M495-V538 HydrophobicContact CG-CG1 3.92Å; M495-V538 HydrophobicContact CG-CG2 4.35Å; M495-V538 HydrophobicContact SD-CB 3.98Å; M495-V538 HydrophobicContact SD-CG1 3.97Å; R531-V538 HydrophobicContact CB-CG1 3.97Å; R531-V538 PolarHBondContact NH1-O 3.18Å; R531-V538 PolarHBondContact NH2-O 3.48Å; Y532-V538 VanDerWaalsContact C-CG2 3.48Å; S534-V538 WeakPolarHBondContact O-CG2 3.43Å; S534-V538 PolarHBondContact O-N 3.36Å; I535-V538 PolarHBondContact O-N 3.19Å
539I82.6Confident93.7Very high16 Ų1634.7 Ų34.78%0.08215%0.153CC..SBendtrans-107.4-87.7-178.7-149.8-178.7000109.3T237 M493 M495 I535T237-I539 WeakPolarHBondContact CA-O 3.38Å; T237-I539 WeakPolarHBondContact CB-O 3.48Å; T237-I539 HydrophobicContact CG2-CG1 4.19Å; T237-I539 WeakPolarHBondContact CG2-O 3.48Å; M493-I539 HydrophobicContact CE-CG1 4.24Å; M493-I539 HydrophobicContact SD-CB 4.02Å; M493-I539 HydrophobicContact SD-CD1 4.25Å; M493-I539 HydrophobicContact SD-CG1 3.97Å; M495-I539 HydrophobicContact CE-CG2 4.4Å; M495-I539 HydrophobicContact SD-CB 3.84Å; M495-I539 HydrophobicContact SD-CG2 3.77Å; I535-I539 HydrophobicContact CG2-CG2 3.73Å; I535-I539 WeakPolarHBondContact O-CG2 3.48Å; I535-I539 PolarHBondContact O-N 3.42Å
540Y79.8Confident93.8Very high52 Ų5224.4 Ų24.420%0.20411%0.114CC..  trans-164.6170.3-177.953.7-101.4000110.1T237 R437 I535 A542T237-Y540 HydrophobicContact CG2-CD1 4.07Å; R437-Y540 PolarHBondContact NH2-OH 3.36Å; I535-Y540 PolarHBondContact O-N 2.9Å; Y540-A542 HydrophobicContact CD2-CB 4.14Å; Y540-A542 HydrophobicContact CE2-CB 3.81Å; Y540-A542 PolarHBondContact O-N 3.21Å
541Q87.6Confident93.8Very high82 Ų8224.4 Ų24.438%0.38311%0.114SC..  trans-65.7118173.1-174.9177.719.900111G447 G499 Y500 I536G447-Q541 WeakPolarHBondContact CA-O 3.38Å; G499-Q541 WeakPolarHBondContact O-CA 3.43Å; Y500-Q541 PolarHBondContact O-NE2 3.37Å; I536-Q541 HydrophobicContact CD1-CB 3.91Å; I536-Q541 HydrophobicContact CD1-CG 3.93Å; I536-Q541 HydrophobicContact CG1-CB 4.02Å
542A86.5Confident94Very high4 Ų423.7 Ų23.73%0.03312%0.115CC..  trans-133.4122.3-178.400000109.9G499 Y500 I535 Y540G499-A542 CarbonylContact C-O 3.6Å; G499-A542 PolarHBondContact O-N 2.95Å; Y500-A542 VanDerWaalsContact CA-O 3.31Å; Y500-A542 WeakPolarHBondContact CA-O 3.2Å; Y500-A542 PolarHBondContact N-O 3.43Å; I535-A542 HydrophobicContact CG2-CB 4.48Å; Y540-A542 HydrophobicContact CD2-CB 4.14Å; Y540-A542 HydrophobicContact CE2-CB 3.81Å; Y540-A542 PolarHBondContact O-N 3.21Å
543S93.5Very high94Very high0 Ų024.4 Ų24.40%012%0.121CC..SBendtrans-97.9151.9-178.864.30000112.8R437 G442 L445 P446 A448 S545R437-S543 WeakPolarHBondContact CD-O 3.43Å; G442-S543 VanDerWaalsContact O-CB 3.28Å; G442-S543 WeakPolarHBondContact O-CB 3.4Å; L445-S543 WeakPolarHBondContact O-CB 3.37Å; L445-S543 PolarHBondContact O-OG 2.8Å; P446-S543 WeakPolarHBondContact O-CB 3.29Å; A448-S543 WeakPolarHBondContact CB-OG 3.41Å; S543-S545 PolarHBondContact O-N 3.46Å
544G97.6Very high94Very high0 Ų026.5 Ų26.50%014%0.143CC..SBendtrans67.933.2176.800000114.4N436 R437 N438 W439 A441N436-G544 CarbonylContact C-O 3.57Å; R437-G544 CarbonylContact C-O 3.54Å; R437-G544 WeakPolarHBondContact CA-O 3.31Å; R437-G544 PolarHBondContact N-O 3.36Å; N438-G544 PolarHBondContact N-O 3.45Å; W439-G544 WeakPolarHBondContact CB-O 3.47Å; W439-G544 VanDerWaalsContact CD1-O 3.25Å; W439-G544 PolarHBondContact N-O 3.43Å; W439-G544 VanDerWaalsContact O-CA 3.25Å; W439-G544 WeakPolarHBondContact O-CA 3.27Å; A441-G544 WeakPolarHBondContact O-CA 3.45Å; A441-G544 PolarHBondContact O-N 3Å
545S97.7Very high94Very high3 Ų326.3 Ų26.32%0.02114%0.141CC..  trans-84.9154.7-179.477.40000113.2N436 S543 V547 D548 W549N436-S545 VanDerWaalsContact OD1-CA 3.25Å; N436-S545 WeakPolarHBondContact OD1-CA 3.31Å; N436-S545 WeakPolarHBondContact OD1-CB 3.2Å; S543-S545 PolarHBondContact O-N 3.46Å; S545-V547 PolarHBondContact O-N 2.93Å; S545-D548 WeakPolarHBondContact OG-CB 3.18Å; S545-D548 PolarHBondContact OG-OD2 3.17Å; S545-W549 PolarHBondContact O-N 3.26Å
546T98.7Very high94.2Very high1 Ų127.2 Ų27.21%0.00614%0.144CC..Hα-helixtrans-54.2-53.9-179.4-530000112.1N436 W439 F484 D548 W549 T550N436-T546 PolarHBondContact OD1-N 3.13Å; N436-T546 PolarHBondContact OD1-OG1 2.86Å; W439-T546 HydrophobicContact CD2-CG2 4.42Å; W439-T546 VanDerWaalsContact CE2-OG1 3.28Å; W439-T546 HydrophobicContact CH2-CG2 3.81Å; W439-T546 HydrophobicContact CZ2-CG2 3.56Å; W439-T546 HydrophobicContact CZ3-CG2 4.35Å; W439-T546 PolarHBondContact NE1-OG1 3.3Å; F484-T546 HydrophobicContact CD1-CG2 4.15Å; F484-T546 HydrophobicContact CE1-CG2 3.29Å; F484-T546 HydrophobicContact CZ-CG2 3.67Å; T546-D548 PolarHBondContact O-N 3.39Å; T546-W549 PolarHBondContact O-N 3.24Å; T546-T550 HydrophobicContact CG2-CG2 4.47Å; T546-T550 WeakPolarHBondContact O-CG2 3.47Å; T546-T550 PolarHBondContact O-N 3.19Å; T546-T550 PolarHBondContact O-OG1 3.11Å
547V98.5Very high94.5Very high3 Ų326.1 Ų26.12%0.01814%0.138CC..Hα-helixtrans-77.8-24.8-169-630000113.3P497 I535 S545 W549 T550 Y551 Y559 T560P497-V547 HydrophobicContact CG-CB 4.21Å; P497-V547 HydrophobicContact CG-CG2 4.2Å; P497-V547 WeakPolarHBondContact CG-O 3.4Å; I535-V547 HydrophobicContact CD1-CG2 3.42Å; I535-V547 VanDerWaalsContact CD1-CG2 3.42Å; S545-V547 PolarHBondContact O-N 2.93Å; V547-W549 VanDerWaalsContact C-N 3.35Å; V547-T550 VanDerWaalsContact CA-OG1 3.32Å; V547-T550 WeakPolarHBondContact CA-OG1 3.45Å; V547-T550 PolarHBondContact O-OG1 3.17Å; V547-Y551 VanDerWaalsContact O-CB 3.3Å; V547-Y551 WeakPolarHBondContact O-CB 3.33Å; V547-Y551 PolarHBondContact O-N 3.39Å; V547-Y551 VanDerWaalsContact O-N 3.14Å; V547-Y559 VanDerWaalsContact CG1-O 3.29Å; V547-Y559 WeakPolarHBondContact CG1-O 3.29Å; V547-T560 HydrophobicContact CG2-CG2 4.15Å
548D98.8Very high95Very high0 Ų020.6 Ų20.60%011%0.109CC..Hα-helixtrans-63.4-45.9169.3-69.4-15.7000109.8A441 P497 Y498 G499 Y500 S545 T546 E552A441-D548 HydrophobicContact CB-CB 3.68Å; P497-D548 WeakPolarHBondContact CB-OD1 3.46Å; Y498-D548 WeakPolarHBondContact CA-OD1 3.34Å; Y498-D548 HydrophobicContact CD1-CB 4.14Å; G499-D548 WeakPolarHBondContact CA-OD2 3.45Å; G499-D548 VanDerWaalsContact N-CG 3.32Å; G499-D548 PolarHBondContact N-OD1 2.89Å; G499-D548 PolarHBondContact N-OD2 2.82Å; Y500-D548 HydrophobicContact CD1-CB 4.11Å; Y500-D548 WeakPolarHBondContact CD1-OD2 3.38Å; Y500-D548 HydrophobicContact CE1-CB 4.39Å; Y500-D548 PolarHBondContact N-OD2 2.97Å; S545-D548 WeakPolarHBondContact OG-CB 3.18Å; S545-D548 PolarHBondContact OG-OD2 3.17Å; T546-D548 PolarHBondContact O-N 3.39Å; D548-E552 WeakPolarHBondContact O-CG 3.28Å; D548-E552 PolarHBondContact O-N 3.17Å
549W98.9Very high95.5Very high1 Ų120.2 Ų20.20%0.00411%0.106CC..Hα-helixtrans-65.3-46.6179177.680.8000112.6W439 A441 H463 V472 V475 S545 T546 V547 Y551 E552 Q553W439-W549 HydrophobicContact CB-CB 3.88Å; W439-W549 HydrophobicContact CB-CG 4.34Å; W439-W549 HydrophobicContact CE3-CB 4.11Å; W439-W549 AromaticContact CE3-CD2 3.67Å; W439-W549 HydrophobicContact CE3-CD2 3.67Å; W439-W549 AromaticContact CE3-CE3 3.43Å; W439-W549 HydrophobicContact CE3-CE3 3.43Å; W439-W549 VanDerWaalsContact CE3-CE3 3.43Å; W439-W549 AromaticContact CE3-CG 3.96Å; W439-W549 HydrophobicContact CE3-CG 3.96Å; W439-W549 HydrophobicContact CE3-CZ3 4.16Å; W439-W549 HydrophobicContact CZ3-CD2 4.08Å; W439-W549 AromaticContact CZ3-CE3 3.39Å; W439-W549 HydrophobicContact CZ3-CE3 3.39Å; W439-W549 AromaticContact CZ3-CZ3 3.68Å; W439-W549 HydrophobicContact CZ3-CZ3 3.68Å; A441-W549 HydrophobicContact CB-CB 3.84Å; H463-W549 AromaticContact CE1-NE1 3.91Å; H463-W549 AromaticContact NE2-NE1 3.8Å; V472-W549 HydrophobicContact CB-CH2 4.11Å; V472-W549 HydrophobicContact CB-CZ2 4.17Å; V472-W549 HydrophobicContact CG1-CH2 4.1Å; V472-W549 HydrophobicContact CG1-CZ2 3.75Å; V472-W549 HydrophobicContact CG2-CH2 3.91Å; V472-W549 HydrophobicContact CG2-CZ2 3.87Å; V472-W549 HydrophobicContact CG2-CZ3 4.26Å; V475-W549 HydrophobicContact CB-CH2 4Å; V475-W549 HydrophobicContact CB-CZ3 4.14Å; V475-W549 HydrophobicContact CG1-CH2 3.88Å; V475-W549 HydrophobicContact CG1-CZ3 3.96Å; V475-W549 HydrophobicContact CG2-CZ3 4.29Å; S545-W549 PolarHBondContact O-N 3.26Å; T546-W549 PolarHBondContact O-N 3.24Å; V547-W549 VanDerWaalsContact C-N 3.35Å; W549-Y551 VanDerWaalsContact C-N 3.29Å; W549-Y551 PolarHBondContact O-N 2.97Å; W549-E552 CarbonylContact O-C 3.57Å; W549-E552 PolarHBondContact O-N 3.23Å; W549-E552 VanDerWaalsContact O-N 3.16Å; W549-Q553 HydrophobicContact CD2-CG 3.91Å; W549-Q553 VanDerWaalsContact CE2-CG 3.5Å; W549-Q553 HydrophobicContact CE3-CG 4.18Å; W549-Q553 HydrophobicContact CH2-CG 3.74Å; W549-Q553 HydrophobicContact CZ2-CG 3.42Å; W549-Q553 VanDerWaalsContact CZ2-CG 3.42Å; W549-Q553 HydrophobicContact CZ3-CG 4.1Å; W549-Q553 WeakPolarHBondContact O-CG 3.35Å; W549-Q553 PolarHBondContact O-N 3.42Å
550T98.9Very high96.3Very high0 Ų019.8 Ų19.80%011%0.105CC..Hα-helixtrans-63.2-37.8-179.4560000111.7F484 T546 V547 Q553 G554 I555 S558F484-T550 HydrophobicContact CB-CG2 4.11Å; F484-T550 HydrophobicContact CD1-CG2 3.88Å; F484-T550 HydrophobicContact CD2-CG2 3.41Å; F484-T550 VanDerWaalsContact CD2-CG2 3.41Å; F484-T550 HydrophobicContact CE1-CG2 4.13Å; F484-T550 HydrophobicContact CE2-CG2 3.66Å; F484-T550 HydrophobicContact CG-CG2 3.53Å; F484-T550 HydrophobicContact CZ-CG2 4.01Å; T546-T550 HydrophobicContact CG2-CG2 4.47Å; T546-T550 WeakPolarHBondContact O-CG2 3.47Å; T546-T550 PolarHBondContact O-N 3.19Å; T546-T550 PolarHBondContact O-OG1 3.11Å; V547-T550 VanDerWaalsContact CA-OG1 3.32Å; V547-T550 WeakPolarHBondContact CA-OG1 3.45Å; V547-T550 PolarHBondContact O-OG1 3.17Å; T550-Q553 PolarHBondContact O-N 2.65Å; T550-G554 PolarHBondContact O-N 2.92Å; T550-I555 HydrophobicContact CG2-CD1 4.45Å; T550-I555 VanDerWaalsContact O-CB 3.31Å; T550-I555 WeakPolarHBondContact O-CB 3.36Å; T550-I555 PolarHBondContact O-N 3.07Å; T550-S558 WeakPolarHBondContact CB-OG 3.45Å; T550-S558 VanDerWaalsContact OG1-CB 3.3Å; T550-S558 WeakPolarHBondContact OG1-CB 3.41Å; T550-S558 PolarHBondContact OG1-OG 3.16Å
551Y98.8Very high97.2Very high15 Ų1517.3 Ų17.36%0.05910%0.095CC..Hα-helixtrans-66.3-40.8174.2-174.9-91.8000112.3P497 Y498 V505 K506 D507 L511 V547 W549 Q553 G554 K556 S558P497-Y551 HydrophobicContact CB-CG 4.34Å; P497-Y551 HydrophobicContact CG-CG 4.14Å; Y498-Y551 HydrophobicContact CE1-CD1 4.11Å; Y498-Y551 HydrophobicContact CE2-CE1 4.38Å; Y498-Y551 AromaticContact CZ-CD1 3.77Å; Y498-Y551 AromaticContact CZ-CE1 3.97Å; Y498-Y551 WeakPolarHBondContact OH-CD1 3.48Å; Y498-Y551 WeakPolarHBondContact OH-CE1 3.44Å; V505-Y551 HydrophobicContact CB-CE1 3.88Å; V505-Y551 HydrophobicContact CB-CE2 4.35Å; V505-Y551 WeakPolarHBondContact CB-OH 3.32Å; V505-Y551 HydrophobicContact CG1-CD1 3.89Å; V505-Y551 HydrophobicContact CG1-CE1 3.49Å; V505-Y551 VanDerWaalsContact CG1-CE1 3.49Å; V505-Y551 HydrophobicContact CG1-CE2 4.23Å; V505-Y551 HydrophobicContact CG1-CG 4.42Å; K506-Y551 WeakPolarHBondContact CG-OH 3.44Å; K506-Y551 PolarHBondContact N-OH 3.32Å; D507-Y551 PolarHBondContact N-OH 2.92Å; D507-Y551 PolarHBondContact OD2-OH 3.1Å; D507-Y551 VanDerWaalsContact OD2-OH 3.05Å; L511-Y551 HydrophobicContact CD1-CD2 4.4Å; L511-Y551 HydrophobicContact CD1-CE2 3.87Å; V547-Y551 VanDerWaalsContact O-CB 3.3Å; V547-Y551 WeakPolarHBondContact O-CB 3.33Å; V547-Y551 PolarHBondContact O-N 3.39Å; V547-Y551 VanDerWaalsContact O-N 3.14Å; W549-Y551 VanDerWaalsContact C-N 3.29Å; W549-Y551 PolarHBondContact O-N 2.97Å; Y551-Q553 PolarHBondContact O-N 3.36Å; Y551-G554 WeakPolarHBondContact O-CA 3.49Å; Y551-G554 PolarHBondContact O-N 2.93Å; Y551-K556 WeakPolarHBondContact CD2-O 3.35Å; Y551-K556 HydrophobicContact CE2-CB 4.34Å; Y551-S558 PolarHBondContact N-OG 3.06Å
552E98.5Very high97.7Very high72 Ų7214.7 Ų14.734%0.3368%0.082SC..Hα-helixtrans-64.8-25172.6-73.5-178.6177.500113.1Y498 Y500 D548 W549 G554Y498-E552 HydrophobicContact CE1-CG 3.98Å; Y500-E552 VanDerWaalsContact CE1-OE1 3.23Å; Y500-E552 WeakPolarHBondContact CE1-OE1 3.47Å; Y500-E552 VanDerWaalsContact CZ-OE1 3.31Å; Y500-E552 PolarHBondContact OH-OE1 3.12Å; D548-E552 WeakPolarHBondContact O-CG 3.28Å; D548-E552 PolarHBondContact O-N 3.17Å; W549-E552 CarbonylContact O-C 3.57Å; W549-E552 PolarHBondContact O-N 3.23Å; W549-E552 VanDerWaalsContact O-N 3.16Å; E552-G554 PolarHBondContact O-N 2.93Å
553Q98.3Very high98.3Very high87 Ų8714.5 Ų14.541%0.4078%0.081SC..THydrogen-bonded Turntrans-78.3-0.6170.1-60.2-41.9-8400113.6W549 T550 Y551W549-Q553 HydrophobicContact CD2-CG 3.91Å; W549-Q553 VanDerWaalsContact CE2-CG 3.5Å; W549-Q553 HydrophobicContact CE3-CG 4.18Å; W549-Q553 HydrophobicContact CH2-CG 3.74Å; W549-Q553 HydrophobicContact CZ2-CG 3.42Å; W549-Q553 VanDerWaalsContact CZ2-CG 3.42Å; W549-Q553 HydrophobicContact CZ3-CG 4.1Å; W549-Q553 WeakPolarHBondContact O-CG 3.35Å; W549-Q553 PolarHBondContact O-N 3.42Å; T550-Q553 PolarHBondContact O-N 2.65Å; Y551-Q553 PolarHBondContact O-N 3.36Å
554G98Very high98.5Very high49 Ų4915.8 Ų15.851%0.5059%0.086SC..THydrogen-bonded Turntrans93.87.117900000115T550 Y551 E552 K556T550-G554 PolarHBondContact O-N 2.92Å; Y551-G554 WeakPolarHBondContact O-CA 3.49Å; Y551-G554 PolarHBondContact O-N 2.93Å; E552-G554 PolarHBondContact O-N 2.93Å; G554-K556 PolarHBondContact O-N 2.97Å; G554-K556 VanDerWaalsContact O-N 3.11Å
555I98.6Very high98.4Very high7 Ų716.3 Ų16.34%0.0369%0.088CC..  trans-81.986.9173.3-50.1176.4000108.2V475 I481 K482 F484 T550 Y557 S558V475-I555 HydrophobicContact CG1-CD1 3.72Å; I481-I555 HydrophobicContact CB-CD1 4.03Å; I481-I555 HydrophobicContact CG2-CD1 3.94Å; I481-I555 HydrophobicContact CG2-CG2 4.28Å; K482-I555 WeakPolarHBondContact O-CG2 3.22Å; F484-I555 HydrophobicContact CB-CG2 4.06Å; F484-I555 HydrophobicContact CD2-CD1 4.41Å; T550-I555 HydrophobicContact CG2-CD1 4.45Å; T550-I555 VanDerWaalsContact O-CB 3.31Å; T550-I555 WeakPolarHBondContact O-CB 3.36Å; T550-I555 PolarHBondContact O-N 3.07Å; I555-Y557 PolarHBondContact O-N 3.49Å; I555-S558 PolarHBondContact O-OG 3.48Å
556K98.5Very high98Very high30 Ų3019.3 Ų19.313%0.1311%0.107CC..SBendtrans-61.3-40.1-170.1140.2179.1-175.6163.90114D507 E510 L511 Y551 G554 S558 Y601D507-K556 HydrophobicContact CB-CD 4.21Å; D507-K556 HydrophobicContact CB-CG 4.37Å; D507-K556 WeakPolarHBondContact OD1-CE 3.38Å; D507-K556 IonicContact OD1-NZ 3.46Å; D507-K556 PolarHBondContact OD1-NZ 3.47Å; E510-K556 IonicContact OE1-NZ 3.09Å; E510-K556 WeakPolarHBondContact OE2-CE 3.06Å; E510-K556 IonicContact OE2-NZ 3.49Å; E510-K556 PolarHBondContact OE2-NZ 3.23Å; L511-K556 WeakPolarHBondContact CD2-O 3.43Å; Y551-K556 WeakPolarHBondContact CD2-O 3.35Å; Y551-K556 HydrophobicContact CE2-CB 4.34Å; G554-K556 PolarHBondContact O-N 2.97Å; G554-K556 VanDerWaalsContact O-N 3.11Å; K556-S558 PolarHBondContact O-N 3.31Å; K556-Y601 VanDerWaalsContact CA-OH 3.28Å; K556-Y601 WeakPolarHBondContact CA-OH 3.5Å; K556-Y601 HydrophobicContact CB-CE1 3.82Å; K556-Y601 HydrophobicContact CB-CE2 3.78Å; K556-Y601 WeakPolarHBondContact CB-OH 3.35Å; K556-Y601 HydrophobicContact CD-CD1 3.87Å; K556-Y601 HydrophobicContact CD-CE1 3.42Å; K556-Y601 VanDerWaalsContact CD-CE1 3.42Å; K556-Y601 HydrophobicContact CG-CD1 4.46Å; K556-Y601 HydrophobicContact CG-CE1 3.54Å; K556-Y601 HydrophobicContact CG-CE2 4.43Å; K556-Y601 PolarHBondContact N-OH 3.22Å
557Y98.8Very high97.2Very high2 Ų219.3 Ų19.31%0.00811%0.107CC..EExtended strand (participates in β ladder)trans-82.764.3175.5-56.2-51.7000111.3A483 F484 E510 L511 L514 I555 H595 T596 N599 Y601A483-Y557 CarbonylContact C-O 3.55Å; A483-Y557 VanDerWaalsContact CA-O 3.23Å; A483-Y557 WeakPolarHBondContact CA-O 3.4Å; F484-Y557 PolarHBondContact N-O 3.32Å; E510-Y557 VanDerWaalsContact OE1-CE1 3.3Å; E510-Y557 WeakPolarHBondContact OE1-CE1 3.41Å; E510-Y557 PolarHBondContact OE1-OH 2.99Å; L511-Y557 HydrophobicContact CD2-CD1 3.85Å; L511-Y557 HydrophobicContact CD2-CE1 4.47Å; L514-Y557 HydrophobicContact CD2-CD1 4.01Å; L514-Y557 HydrophobicContact CD2-CE1 4.23Å; I555-Y557 PolarHBondContact O-N 3.49Å; Y557-H595 AromaticContact CE1-CD2 3.49Å; Y557-H595 VanDerWaalsContact CE1-CD2 3.49Å; Y557-H595 WeakPolarHBondContact CE1-CD2 3.46Å; Y557-H595 AromaticContact CE1-NE2 3.64Å; Y557-H595 AromaticContact CZ-CD2 3.34Å; Y557-H595 AromaticContact CZ-NE2 3.57Å; Y557-H595 PolarHBondContact OH-CD2 3.01Å; Y557-H595 PolarHBondContact OH-NE2 3.23Å; Y557-T596 HydrophobicContact CD2-CG2 3.83Å; Y557-T596 VanDerWaalsContact CD2-OG1 3.27Å; Y557-T596 WeakPolarHBondContact CD2-OG1 3.35Å; Y557-T596 HydrophobicContact CE2-CG2 4.25Å; Y557-N599 VanDerWaalsContact OH-CB 3.24Å; Y557-N599 WeakPolarHBondContact OH-CB 3.26Å; Y557-Y601 AromaticContact CD2-CE1 3.6Å; Y557-Y601 HydrophobicContact CD2-CE1 3.6Å; Y557-Y601 AromaticContact CD2-CZ 3.76Å; Y557-Y601 WeakPolarHBondContact CD2-OH 3.38Å; Y557-Y601 HydrophobicContact CE1-CE1 4.22Å; Y557-Y601 HydrophobicContact CE2-CD1 4.03Å; Y557-Y601 AromaticContact CE2-CE1 3.16Å; Y557-Y601 HydrophobicContact CE2-CE1 3.16Å; Y557-Y601 AromaticContact CE2-CZ 3.82Å; Y557-Y601 HydrophobicContact CG-CE1 4.3Å; Y557-Y601 AromaticContact CZ-CE1 3.47Å; Y557-Y601 VanDerWaalsContact CZ-CE1 3.47Å; Y557-Y601 PolarHBondContact N-OH 3.34Å
558S98.9Very high96.6Very high0 Ų022.7 Ų22.70%013%0.131CC..EExtended strand (participates in β ladder)trans-97118.4173.8-670000110F484 P497 T550 Y551 I555 K556F484-S558 CarbonylContact O-C 3.42Å; F484-S558 WeakPolarHBondContact O-CA 3.47Å; P497-S558 VanDerWaalsContact CD-O 3.22Å; P497-S558 WeakPolarHBondContact CD-O 3.47Å; T550-S558 WeakPolarHBondContact CB-OG 3.45Å; T550-S558 VanDerWaalsContact OG1-CB 3.3Å; T550-S558 WeakPolarHBondContact OG1-CB 3.41Å; T550-S558 PolarHBondContact OG1-OG 3.16Å; Y551-S558 PolarHBondContact N-OG 3.06Å; I555-S558 PolarHBondContact O-OG 3.48Å; K556-S558 PolarHBondContact O-N 3.31Å
559Y98.9Very high96.1Very high1 Ų126.5 Ų26.50%0.00415%0.145CC..EExtended strand (participates in β ladder)trans-134.6150.8-176.2-73.7-82.7000111.8F484 I485 S486 L494 M495 Y496 L511 L514 A515 V547 L592F484-Y559 PolarHBondContact O-N 3.23Å; I485-Y559 VanDerWaalsContact CA-O 3.3Å; I485-Y559 WeakPolarHBondContact CA-O 3.35Å; S486-Y559 PolarHBondContact N-O 3.43Å; L494-Y559 HydrophobicContact CD1-CD1 3.89Å; L494-Y559 HydrophobicContact CD1-CG 4.29Å; L494-Y559 HydrophobicContact CG-CD1 4.29Å; M495-Y559 CarbonylContact O-C 3.59Å; M495-Y559 VanDerWaalsContact O-CA 3.31Å; M495-Y559 WeakPolarHBondContact O-CA 3.35Å; M495-Y559 WeakPolarHBondContact O-CD1 3.22Å; Y496-Y559 HydrophobicContact CD1-CE1 4.08Å; Y496-Y559 HydrophobicContact CG-CE1 4.36Å; L511-Y559 WeakPolarHBondContact CA-OH 3.39Å; L511-Y559 HydrophobicContact CD2-CE2 4Å; L511-Y559 WeakPolarHBondContact CD2-OH 3.5Å; L511-Y559 PolarHBondContact O-OH 3.41Å; L514-Y559 WeakPolarHBondContact CB-OH 3.46Å; L514-Y559 HydrophobicContact CD2-CE2 4.05Å; A515-Y559 HydrophobicContact CB-CE1 4.04Å; V547-Y559 VanDerWaalsContact CG1-O 3.29Å; V547-Y559 WeakPolarHBondContact CG1-O 3.29Å; Y559-L592 HydrophobicContact CD2-CD1 4.09Å; Y559-L592 HydrophobicContact CD2-CD2 4.07Å; Y559-L592 HydrophobicContact CE2-CD2 3.88Å; Y559-L592 HydrophobicContact CG-CD1 4.16Å; Y559-L592 HydrophobicContact CG-CD2 4.48Å
560T98.8Very high95.7Very high7 Ų726.5 Ų26.54%0.04315%0.146CC..EExtended strand (participates in β ladder)trans-128.1136.1170.8-173.60000111.2S486 H488 M495 I535 V547S486-T560 WeakPolarHBondContact O-CA 3.45Å; S486-T560 WeakPolarHBondContact O-CB 3.27Å; S486-T560 PolarHBondContact O-OG1 3.09Å; H488-T560 PolarHBondContact CD2-OG1 3.3Å; M495-T560 HydrophobicContact CB-CG2 3.76Å; M495-T560 HydrophobicContact CE-CG2 3.89Å; M495-T560 PolarHBondContact N-O 3.35Å; M495-T560 PolarHBondContact O-N 2.55Å; I535-T560 HydrophobicContact CD1-CG2 4.08Å; I535-T560 HydrophobicContact CG1-CG2 4.11Å; V547-T560 HydrophobicContact CG2-CG2 4.15Å
561F98.9Very high95.3Very high0 Ų026.9 Ų26.90%015%0.147CC..EExtended strand (participates in β ladder)trans-101140.8174.7-81.2-95.9000109.7I485 S486 I487 H488 M493 L494 L522 Y530 L563 T585 A588 L589 L592I485-F561 HydrophobicContact CG2-CD2 3.75Å; I485-F561 HydrophobicContact CG2-CE2 3.84Å; S486-F561 PolarHBondContact O-N 3.14Å; S486-F561 VanDerWaalsContact O-N 3.1Å; I487-F561 HydrophobicContact CG1-CB 4.44Å; I487-F561 HydrophobicContact CG1-CD2 4.4Å; I487-F561 HydrophobicContact CG2-CB 4.13Å; H488-F561 CarbonylContact C-O 3.01Å; H488-F561 VanDerWaalsContact CA-O 3.31Å; H488-F561 WeakPolarHBondContact CA-O 3.28Å; H488-F561 VanDerWaalsContact CB-O 3.23Å; H488-F561 WeakPolarHBondContact CB-O 3.38Å; H488-F561 PolarHBondContact N-O 3.45Å; M493-F561 CarbonylContact O-C 3.59Å; M493-F561 WeakPolarHBondContact O-CA 3.41Å; L494-F561 HydrophobicContact CB-CD1 4.5Å; L494-F561 HydrophobicContact CB-CE1 4.35Å; L494-F561 HydrophobicContact CD1-CD1 4.14Å; L494-F561 HydrophobicContact CD1-CD2 3.79Å; L494-F561 HydrophobicContact CD1-CE1 3.9Å; L494-F561 HydrophobicContact CD1-CE2 3.53Å; L494-F561 HydrophobicContact CD1-CG 4.09Å; L494-F561 HydrophobicContact CD1-CZ 3.59Å; L494-F561 HydrophobicContact CD2-CE1 4.29Å; L494-F561 HydrophobicContact CD2-CZ 4.08Å; L494-F561 HydrophobicContact CG-CE1 4.41Å; L494-F561 HydrophobicContact CG-CZ 4.35Å; L522-F561 HydrophobicContact CD1-CE1 4.48Å; Y530-F561 HydrophobicContact CE1-CD1 4.25Å; F561-L563 HydrophobicContact CB-CD2 4.04Å; F561-L563 HydrophobicContact CD1-CD2 4.26Å; F561-L563 HydrophobicContact CG-CD2 4.46Å; F561-T585 HydrophobicContact CD1-CG2 4.38Å; F561-T585 HydrophobicContact CE1-CG2 4.36Å; F561-A588 HydrophobicContact CE1-CB 3.77Å; F561-A588 HydrophobicContact CZ-CB 3.63Å; F561-L589 HydrophobicContact CE2-CD2 4.07Å; F561-L592 HydrophobicContact CE2-CD1 3.84Å; F561-L592 HydrophobicContact CZ-CD1 4.17Å
562E98Very high95Very high26 Ų2626.3 Ų26.312%0.12115%0.146CC..EExtended strand (participates in β ladder)trans-110.1111156.5-68.1-71.9-179.800106.7H488 A489 Y490 Q492 M493 M495 Y530H488-E562 VanDerWaalsContact CB-OE2 3.25Å; H488-E562 WeakPolarHBondContact CB-OE2 3.31Å; H488-E562 CarbonylContact O-C 3.54Å; H488-E562 WeakPolarHBondContact O-CA 3.31Å; A489-E562 WeakPolarHBondContact CA-OE2 3.21Å; A489-E562 PolarHBondContact N-OE2 3.26Å; Y490-E562 PolarHBondContact N-OE2 3.33Å; Q492-E562 CarbonylContact C-O 3.58Å; Q492-E562 WeakPolarHBondContact CA-O 3.44Å; Q492-E562 PolarHBondContact N-O 3.31Å; M493-E562 HydrophobicContact CB-CB 3.96Å; M493-E562 HydrophobicContact CB-CG 4.25Å; M493-E562 HydrophobicContact CG-CB 4.33Å; M493-E562 PolarHBondContact N-O 3.5Å; M493-E562 PolarHBondContact O-N 3.23Å; M495-E562 HydrophobicContact CE-CG 3.62Å; Y530-E562 VanDerWaalsContact CE1-O 3.25Å; Y530-E562 WeakPolarHBondContact CE1-O 3.5Å
563L98.6Very high94.6Very high0 Ų023 Ų230%013%0.13CC..EExtended strand (participates in β ladder)trans-75.1-168.8-174.6-61.2-174.3000112.5V366 T367 I487 H488 A489 Y490 S491 Q492 Y530 F561 T581 T585V366-L563 HydrophobicContact CG1-CB 4.26Å; V366-L563 HydrophobicContact CG1-CD1 4.35Å; T367-L563 HydrophobicContact CG2-CD1 4.28Å; I487-L563 HydrophobicContact CG2-CD1 3.61Å; I487-L563 HydrophobicContact CG2-CD2 4.08Å; I487-L563 HydrophobicContact CG2-CG 3.75Å; H488-L563 VanDerWaalsContact O-CG 3.31Å; H488-L563 WeakPolarHBondContact O-CG 3.35Å; H488-L563 PolarHBondContact O-N 3.29Å; A489-L563 HydrophobicContact CB-CB 4.15Å; Y490-L563 WeakPolarHBondContact CA-O 3.38Å; S491-L563 PolarHBondContact N-O 2.81Å; Q492-L563 PolarHBondContact N-O 3.32Å; Y530-L563 WeakPolarHBondContact OH-CA 3.02Å; F561-L563 HydrophobicContact CB-CD2 4.04Å; F561-L563 HydrophobicContact CD1-CD2 4.26Å; F561-L563 HydrophobicContact CG-CD2 4.46Å; L563-T581 HydrophobicContact CB-CG2 3.99Å; L563-T581 HydrophobicContact CD1-CG2 3.97Å; L563-T581 HydrophobicContact CG-CG2 4.39Å; L563-T585 HydrophobicContact CD2-CG2 3.82Å; L563-T585 WeakPolarHBondContact CD2-OG1 3.31Å
564R96.9Very high94.4Very high28 Ų2820 Ų2011%0.10612%0.118CC..SBendtrans-59153.3174.1-68.7-165.9-172.1-173.44.3111.9Q492 T528 L573 T581 E584Q492-R564 HydrophobicContact CG-CG 4.43Å; T528-R564 HydrophobicContact CG2-CG 4.38Å; T528-R564 PolarHBondContact OG1-NH2 3.04Å; R564-L573 HydrophobicContact CB-CD1 4.35Å; R564-L573 HydrophobicContact CB-CD2 3.96Å; R564-T581 HydrophobicContact CB-CG2 4.34Å; R564-T581 WeakPolarHBondContact CD-OG1 3.41Å; R564-T581 HydrophobicContact CG-CG2 4.28Å; R564-E584 IonicContact CZ-OE1 2.64Å; R564-E584 IonicContact CZ-OE2 2.67Å; R564-E584 IonicContact NE-OE1 3.75Å; R564-E584 PolarHBondContact NE-OE1 2.86Å; R564-E584 IonicContact NE-OE2 3.79Å; R564-E584 VanDerWaalsContact NH2-CD 3.31Å; R564-E584 IonicContact NH2-OE1 2.85Å; R564-E584 PolarHBondContact NH2-OE1 3.04Å; R564-E584 IonicContact NH2-OE2 2.67Å; R564-E584 PolarHBondContact NH2-OE2 3Å
565D95.9Very high94Very high10 Ų1017.9 Ų17.95%0.05310%0.096CC..  cis-105.4-149-4.6647.2000111.5S491 G567 S568 Y569 G570 L573S491-D565 CarbonylContact C-O 3.5Å; S491-D565 WeakPolarHBondContact CA-O 3.43Å; S491-D565 PolarHBondContact N-O 3.35Å; S491-D565 VanDerWaalsContact N-O 3.13Å; D565-G567 VanDerWaalsContact OD1-CA 3.31Å; D565-G567 WeakPolarHBondContact OD1-CA 3.39Å; D565-G567 PolarHBondContact OD1-N 3.24Å; D565-S568 PolarHBondContact OD1-N 3.42Å; D565-S568 WeakPolarHBondContact OD2-CB 3.49Å; D565-S568 PolarHBondContact OD2-N 3.48Å; D565-Y569 VanDerWaalsContact OD2-CD2 3.32Å; D565-Y569 WeakPolarHBondContact OD2-CD2 3.5Å; D565-Y569 PolarHBondContact OD2-N 3.47Å; D565-G570 PolarHBondContact OD1-N 3.23Å; D565-L573 HydrophobicContact CB-CD1 3.88Å
566T89.3Confident93.7Very high67 Ų6725.1 Ų25.141%0.41113%0.127SC..SBendtrans-107.625.6172.854.30000111.7R207 Q492R207-T566 PolarHBondContact NH1-O 3.36Å; R207-T566 PolarHBondContact NH2-O 2.85Å; Q492-T566 HydrophobicContact CB-CG2 4.23Å; Q492-T566 HydrophobicContact CG-CG2 4.1Å
567G82.8Confident93.6Very high0 Ų025.5 Ų25.50%013%0.129CC..SBendtrans107.40.8169.800000116.1M269 Y490 D565 Y569M269-G567 WeakPolarHBondContact CE-O 3.22Å; Y490-G567 VanDerWaalsContact CE2-CA 3.45Å; D565-G567 VanDerWaalsContact OD1-CA 3.31Å; D565-G567 WeakPolarHBondContact OD1-CA 3.39Å; D565-G567 PolarHBondContact OD1-N 3.24Å; G567-Y569 PolarHBondContact O-N 3.32Å
568S85.6Confident93.4Very high74 Ų7425.4 Ų25.452%0.51713%0.129SC..SBendtrans-59.4-35.2175-55.30000111.9D565D565-S568 PolarHBondContact OD1-N 3.42Å; D565-S568 WeakPolarHBondContact OD2-CB 3.49Å; D565-S568 PolarHBondContact OD2-N 3.48Å
569Y87.4Confident93.3Very high80 Ų8028 Ų2831%0.31414%0.142SC..SBendtrans-122.1-24.2172.4-58.8-76.3000112.1D565 G567 F571 L572 L573 P574D565-Y569 VanDerWaalsContact OD2-CD2 3.32Å; D565-Y569 WeakPolarHBondContact OD2-CD2 3.5Å; D565-Y569 PolarHBondContact OD2-N 3.47Å; G567-Y569 PolarHBondContact O-N 3.32Å; Y569-F571 PolarHBondContact O-N 3.29Å; Y569-L572 PolarHBondContact O-N 2.97Å; Y569-L573 HydrophobicContact CD2-CD1 4.28Å; Y569-P574 HydrophobicContact CD1-CG 3.82Å; Y569-P574 VanDerWaalsContact CD2-CD 3.48Å; Y569-P574 HydrophobicContact CD2-CG 4Å; Y569-P574 HydrophobicContact CE1-CG 3.66Å; Y569-P574 HydrophobicContact CE2-CG 3.83Å; Y569-P574 VanDerWaalsContact CG-CD 3.43Å; Y569-P574 HydrophobicContact CG-CG 4Å
570G90.9Very high93.3Very high1 Ų129.4 Ų29.41%0.0115%0.151CC..THydrogen-bonded Turntrans58.9-119.9-177.900000111.1Y490 D565 L572Y490-G570 VanDerWaalsContact CD1-CA 3.41Å; D565-G570 PolarHBondContact OD1-N 3.23Å; G570-L572 PolarHBondContact O-N 3.01Å
571F91.8Very high93.3Very high8 Ų829 Ų294%0.03515%0.149CC..THydrogen-bonded Turntrans-75.3-9.9179.1-51.4-58.8000114.3W233 R363 E364 R416 A489 Y490 Y569W233-F571 HydrophobicContact CB-CE2 3.69Å; W233-F571 HydrophobicContact CB-CZ 4.24Å; W233-F571 AromaticContact CD1-CE2 3.71Å; W233-F571 AromaticContact CD2-CD2 3.65Å; W233-F571 HydrophobicContact CD2-CD2 3.65Å; W233-F571 AromaticContact CD2-CE2 3.66Å; W233-F571 HydrophobicContact CD2-CE2 3.66Å; W233-F571 AromaticContact CE2-CD2 3.82Å; W233-F571 AromaticContact CE3-CD2 3.96Å; W233-F571 HydrophobicContact CE3-CD2 3.96Å; W233-F571 HydrophobicContact CE3-CE2 4.22Å; W233-F571 AromaticContact CG-CD2 3.94Å; W233-F571 HydrophobicContact CG-CD2 3.94Å; W233-F571 AromaticContact CG-CE2 3.42Å; W233-F571 HydrophobicContact CG-CE2 3.42Å; W233-F571 VanDerWaalsContact CG-CE2 3.42Å; W233-F571 HydrophobicContact CG-CZ 4.41Å; W233-F571 HydrophobicContact CZ2-CD2 4.3Å; W233-F571 HydrophobicContact CZ3-CD2 4.4Å; R363-F571 HydrophobicContact CG-CD1 4.12Å; R363-F571 HydrophobicContact CG-CD2 4.28Å; R363-F571 HydrophobicContact CG-CE1 4.41Å; R363-F571 HydrophobicContact CG-CG 4.07Å; R363-F571 VanDerWaalsContact CZ-CE2 3.44Å; R363-F571 VanDerWaalsContact NE-CE2 3.31Å; E364-F571 HydrophobicContact CG-CD1 4.06Å; E364-F571 HydrophobicContact CG-CE1 4.11Å; R416-F571 PolarHBondContact NH2-O 3.25Å; A489-F571 VanDerWaalsContact O-CE1 3.23Å; A489-F571 WeakPolarHBondContact O-CE1 3.31Å; Y490-F571 AromaticContact CD1-CD1 3.69Å; Y490-F571 HydrophobicContact CD1-CD1 3.69Å; Y490-F571 AromaticContact CD1-CE1 3.53Å; Y490-F571 HydrophobicContact CD1-CE1 3.53Å; Y490-F571 HydrophobicContact CD1-CG 4.26Å; Y490-F571 AromaticContact CD1-CZ 3.96Å; Y490-F571 HydrophobicContact CD1-CZ 3.96Å; Y490-F571 HydrophobicContact CE1-CD1 4.1Å; Y490-F571 HydrophobicContact CE1-CD2 4.31Å; Y490-F571 AromaticContact CE1-CE1 3.73Å; Y490-F571 HydrophobicContact CE1-CE1 3.73Å; Y490-F571 AromaticContact CE1-CE2 3.97Å; Y490-F571 HydrophobicContact CE1-CE2 3.97Å; Y490-F571 HydrophobicContact CE1-CG 4.36Å; Y490-F571 AromaticContact CE1-CZ 3.65Å; Y490-F571 HydrophobicContact CE1-CZ 3.65Å; Y569-F571 PolarHBondContact O-N 3.29Å
572L91.6Very high93.3Very high4 Ų429 Ų292%0.02115%0.149CC..  trans-103.237.8-177.6-58.9-177.3000112.1W233 V273 I276 L277 R416 M417 Y569 G570W233-L572 HydrophobicContact CH2-CD1 4.38Å; W233-L572 HydrophobicContact CH2-CG 4.4Å; V273-L572 HydrophobicContact CG1-CD1 4Å; I276-L572 HydrophobicContact CB-CD1 3.95Å; I276-L572 HydrophobicContact CG2-CB 3.66Å; I276-L572 HydrophobicContact CG2-CD1 3.88Å; I276-L572 HydrophobicContact CG2-CG 4.39Å; L277-L572 HydrophobicContact CD2-CD1 4.05Å; L277-L572 HydrophobicContact CD2-CD2 3.49Å; L277-L572 VanDerWaalsContact CD2-CD2 3.49Å; L277-L572 HydrophobicContact CD2-CG 4.44Å; L277-L572 HydrophobicContact CG-CD1 4.17Å; L277-L572 HydrophobicContact CG-CD2 4.47Å; R416-L572 HydrophobicContact CG-CD2 4.26Å; M417-L572 HydrophobicContact CE-CD1 4.23Å; M417-L572 HydrophobicContact CE-CD2 3.54Å; M417-L572 HydrophobicContact CE-CG 4.02Å; Y569-L572 PolarHBondContact O-N 2.97Å; G570-L572 PolarHBondContact O-N 3.01Å
573L91.1Very high93.3Very high2 Ų230.7 Ų30.71%0.0116%0.157CC..  trans-57.1129.7-176.8-166.273.1000110.4Y304 V366 R564 D565 Y569 A575 Q577Y304-L573 WeakPolarHBondContact CE2-O 3.47Å; Y304-L573 PolarHBondContact OH-O 3.12Å; V366-L573 HydrophobicContact CB-CD2 4.12Å; V366-L573 HydrophobicContact CG2-CD2 3.72Å; R564-L573 HydrophobicContact CB-CD1 4.35Å; R564-L573 HydrophobicContact CB-CD2 3.96Å; D565-L573 HydrophobicContact CB-CD1 3.88Å; Y569-L573 HydrophobicContact CD2-CD1 4.28Å; L573-A575 PolarHBondContact O-N 3.2Å; L573-Q577 HydrophobicContact CD1-CB 4.38Å; L573-Q577 HydrophobicContact CD2-CB 3.88Å; L573-Q577 HydrophobicContact CG-CB 3.95Å
574P92.6Very high93.3Very high24 Ų2430.7 Ų30.716%0.15616%0.157CC..  trans-60.7139.8-178.7-27.235000112.2Y569 K576 Q577Y569-P574 HydrophobicContact CD1-CG 3.82Å; Y569-P574 VanDerWaalsContact CD2-CD 3.48Å; Y569-P574 HydrophobicContact CD2-CG 4Å; Y569-P574 HydrophobicContact CE1-CG 3.66Å; Y569-P574 HydrophobicContact CE2-CG 3.83Å; Y569-P574 VanDerWaalsContact CG-CD 3.43Å; Y569-P574 HydrophobicContact CG-CG 4Å; P574-K576 HydrophobicContact CB-CG 4.04Å; P574-K576 PolarHBondContact O-N 3.12Å; P574-Q577 WeakPolarHBondContact O-CB 3.47Å; P574-Q577 PolarHBondContact O-N 2.95Å
575A90.3Very high93.4Very high4 Ų429.3 Ų29.33%0.03315%0.152CC..G310 helixtrans-52-35.6-177.100000113.8A302 L573 Q577 I578A302-A575 CarbonylContact O-C 3.57Å; A302-A575 WeakPolarHBondContact O-CB 3.43Å; L573-A575 PolarHBondContact O-N 3.2Å; A575-Q577 PolarHBondContact O-N 3.36Å; A575-I578 HydrophobicContact CB-CD1 4.1Å; A575-I578 VanDerWaalsContact O-CB 3.29Å; A575-I578 WeakPolarHBondContact O-CB 3.4Å; A575-I578 WeakPolarHBondContact O-CD1 3.43Å; A575-I578 VanDerWaalsContact O-CG1 3.23Å; A575-I578 WeakPolarHBondContact O-CG1 3.39Å; A575-I578 PolarHBondContact O-N 3.48Å
576K92.6Very high93.6Very high159 Ų15929.4 Ų29.469%0.69115%0.151SC*.G310 helixtrans-57.3-16.3173.969.3179.2-178.1-177.20115.3P574 P580P574-K576 HydrophobicContact CB-CG 4.04Å; P574-K576 PolarHBondContact O-N 3.12Å; K576-P580 WeakPolarHBondContact O-CD 3.39Å
577Q95.8Very high94Very high38 Ų3829 Ų2918%0.17815%0.146CC..G310 helixtrans-95.5-4.2176.4-65.4-148.556.400113.6L573 P574 A575 T581L573-Q577 HydrophobicContact CD1-CB 4.38Å; L573-Q577 HydrophobicContact CD2-CB 3.88Å; L573-Q577 HydrophobicContact CG-CB 3.95Å; P574-Q577 WeakPolarHBondContact O-CB 3.47Å; P574-Q577 PolarHBondContact O-N 2.95Å; A575-Q577 PolarHBondContact O-N 3.36Å; Q577-T581 VanDerWaalsContact O-CB 3.26Å; Q577-T581 WeakPolarHBondContact O-CB 3.28Å; Q577-T581 PolarHBondContact O-N 3.44Å; Q577-T581 PolarHBondContact O-OG1 3.06Å
578I95.4Very high94.8Very high0 Ų029 Ų290%015%0.146CC..Hα-helixtrans-59.1-57.4178.8-67.9167.1000110.5Y301 Y304 A369 A575 T581 A582Y301-I578 VanDerWaalsContact O-CG2 3.32Å; Y301-I578 WeakPolarHBondContact O-CG2 3.37Å; Y304-I578 HydrophobicContact CD1-CD1 3.77Å; Y304-I578 HydrophobicContact CD2-CD1 4.36Å; Y304-I578 HydrophobicContact CE1-CD1 3.63Å; Y304-I578 HydrophobicContact CE1-CG1 3.9Å; Y304-I578 HydrophobicContact CE2-CD1 4.26Å; Y304-I578 HydrophobicContact CG-CD1 4.13Å; A369-I578 HydrophobicContact CB-CD1 4.08Å; A369-I578 HydrophobicContact CB-CG1 4.17Å; A369-I578 HydrophobicContact CB-CG2 3.64Å; A575-I578 HydrophobicContact CB-CD1 4.1Å; A575-I578 VanDerWaalsContact O-CB 3.29Å; A575-I578 WeakPolarHBondContact O-CB 3.4Å; A575-I578 WeakPolarHBondContact O-CD1 3.43Å; A575-I578 VanDerWaalsContact O-CG1 3.23Å; A575-I578 WeakPolarHBondContact O-CG1 3.39Å; A575-I578 PolarHBondContact O-N 3.48Å; I578-T581 PolarHBondContact O-N 2.81Å; I578-A582 PolarHBondContact O-N 3.44Å
579I97.1Very high95.4Very high54 Ų5425.4 Ų25.428%0.27712%0.121SC..Hα-helixtrans-61.8-49-178.1-65.1173000111.6A302 T581 A582 E583A302-I579 HydrophobicContact CB-CD1 3.78Å; A302-I579 HydrophobicContact CB-CG1 4.45Å; I579-T581 VanDerWaalsContact C-N 3.26Å; I579-T581 PolarHBondContact O-N 3.31Å; I579-A582 PolarHBondContact O-N 2.86Å; I579-A582 VanDerWaalsContact O-N 3.13Å; I579-E583 HydrophobicContact CG2-CG 4.02Å; I579-E583 WeakPolarHBondContact O-CG 3.39Å; I579-E583 PolarHBondContact O-N 2.92Å
580P98.3Very high95.9Very high31 Ų3122.9 Ų22.920%0.20111%0.113CC..Hα-helixtrans-55.8-39.1175.3-28.935000114.1Y526 K576 E584Y526-P580 HydrophobicContact CD2-CB 4.18Å; Y526-P580 HydrophobicContact CE2-CB 3.78Å; Y526-P580 VanDerWaalsContact CE2-O 3.31Å; Y526-P580 WeakPolarHBondContact CE2-O 3.22Å; K576-P580 WeakPolarHBondContact O-CD 3.39Å; P580-E584 WeakPolarHBondContact O-CG 3.3Å; P580-E584 PolarHBondContact O-N 2.77Å
581T98.6Very high96.3Very high0 Ų023.1 Ų23.10%011%0.114CC..Hα-helixtrans-67.6-43.4177.5-56.30000111.1V366 L563 R564 Q577 I578 I579 E584 T585V366-T581 HydrophobicContact CG2-CG2 3.84Å; L563-T581 HydrophobicContact CB-CG2 3.99Å; L563-T581 HydrophobicContact CD1-CG2 3.97Å; L563-T581 HydrophobicContact CG-CG2 4.39Å; R564-T581 HydrophobicContact CB-CG2 4.34Å; R564-T581 WeakPolarHBondContact CD-OG1 3.41Å; R564-T581 HydrophobicContact CG-CG2 4.28Å; Q577-T581 VanDerWaalsContact O-CB 3.26Å; Q577-T581 WeakPolarHBondContact O-CB 3.28Å; Q577-T581 PolarHBondContact O-N 3.44Å; Q577-T581 PolarHBondContact O-OG1 3.06Å; I578-T581 PolarHBondContact O-N 2.81Å; I579-T581 VanDerWaalsContact C-N 3.26Å; I579-T581 PolarHBondContact O-N 3.31Å; T581-E584 WeakPolarHBondContact O-CG 3.45Å; T581-T585 WeakPolarHBondContact O-CB 3.46Å; T581-T585 PolarHBondContact O-N 2.61Å; T581-T585 VanDerWaalsContact O-N 3.14Å; T581-T585 PolarHBondContact O-OG1 3.42Å
582A98.4Very high96.7Very high0 Ų022.8 Ų22.80%011%0.113CC..Hα-helixtrans-65.3-46.1178.500000111.5W373 F374 I578 I579 E584 T585 W586W373-A582 HydrophobicContact CB-CB 3.9Å; W373-A582 HydrophobicContact CD2-CB 3.69Å; W373-A582 HydrophobicContact CE3-CB 3.75Å; W373-A582 HydrophobicContact CG-CB 3.77Å; F374-A582 HydrophobicContact CE1-CB 4.22Å; F374-A582 WeakPolarHBondContact CE1-O 3.43Å; I578-A582 PolarHBondContact O-N 3.44Å; I579-A582 PolarHBondContact O-N 2.86Å; I579-A582 VanDerWaalsContact O-N 3.13Å; A582-E584 PolarHBondContact O-N 2.95Å; A582-T585 PolarHBondContact O-N 2.73Å; A582-W586 WeakPolarHBondContact O-CB 3.29Å; A582-W586 PolarHBondContact O-N 3.07Å
583E98.6Very high97Very high60 Ų6022.6 Ų22.628%0.2811%0.112SC..Hα-helixtrans-62.5-44.9-177.7-72.8176.3148.100113W373 L525 Y526 I579 W586W373-E583 HydrophobicContact CH2-CB 4.47Å; W373-E583 HydrophobicContact CH2-CG 3.86Å; W373-E583 HydrophobicContact CZ2-CB 4.49Å; W373-E583 HydrophobicContact CZ2-CG 3.46Å; W373-E583 VanDerWaalsContact CZ2-CG 3.46Å; L525-E583 HydrophobicContact CD2-CB 3.61Å; Y526-E583 HydrophobicContact CE2-CB 4.31Å; Y526-E583 PolarHBondContact OH-OE2 2.83Å; I579-E583 HydrophobicContact CG2-CG 4.02Å; I579-E583 WeakPolarHBondContact O-CG 3.39Å; I579-E583 PolarHBondContact O-N 2.92Å; E583-W586 WeakPolarHBondContact O-CB 3.2Å; E583-W586 PolarHBondContact O-N 3.42Å
584E98.8Very high97.4Very high0 Ų024.1 Ų24.10%012%0.12CC..Hα-helixtrans-70.8-38.4178.772.2-173-175.100111.7L522 L525 Y526 T528 R564 P580 T581 A582 W586 L587L522-E584 HydrophobicContact CD1-CG 4.38Å; L522-E584 HydrophobicContact CD2-CB 4.12Å; L522-E584 HydrophobicContact CD2-CG 3.93Å; L522-E584 HydrophobicContact CG-CB 3.89Å; L522-E584 HydrophobicContact CG-CG 3.88Å; L522-E584 WeakPolarHBondContact CG-O 3.31Å; L525-E584 HydrophobicContact CB-CB 4.4Å; L525-E584 HydrophobicContact CD2-CB 4.26Å; Y526-E584 HydrophobicContact CD2-CB 4.05Å; T528-E584 VanDerWaalsContact CB-OE2 3.22Å; T528-E584 WeakPolarHBondContact CB-OE2 3.31Å; T528-E584 PolarHBondContact OG1-OE1 3.43Å; T528-E584 PolarHBondContact OG1-OE2 3.17Å; R564-E584 IonicContact CZ-OE1 2.64Å; R564-E584 IonicContact CZ-OE2 2.67Å; R564-E584 IonicContact NE-OE1 3.75Å; R564-E584 PolarHBondContact NE-OE1 2.86Å; R564-E584 IonicContact NE-OE2 3.79Å; R564-E584 VanDerWaalsContact NH2-CD 3.31Å; R564-E584 IonicContact NH2-OE1 2.85Å; R564-E584 PolarHBondContact NH2-OE1 3.04Å; R564-E584 IonicContact NH2-OE2 2.67Å; R564-E584 PolarHBondContact NH2-OE2 3Å; P580-E584 WeakPolarHBondContact O-CG 3.3Å; P580-E584 PolarHBondContact O-N 2.77Å; T581-E584 WeakPolarHBondContact O-CG 3.45Å; A582-E584 PolarHBondContact O-N 2.95Å; E584-W586 VanDerWaalsContact C-N 3.26Å; E584-W586 PolarHBondContact O-N 2.91Å; E584-L587 WeakPolarHBondContact O-CB 3.12Å; E584-L587 PolarHBondContact O-N 2.58Å
585T98.9Very high97.6Very high0 Ų025 Ų250%012%0.122CC..Hα-helixtrans-64.8-35.1177.3-580000110.8F374 F561 L563 T581 A582 L587 A588 L589F374-T585 HydrophobicContact CE1-CG2 4.45Å; F374-T585 HydrophobicContact CZ-CG2 3.75Å; F561-T585 HydrophobicContact CD1-CG2 4.38Å; F561-T585 HydrophobicContact CE1-CG2 4.36Å; L563-T585 HydrophobicContact CD2-CG2 3.82Å; L563-T585 WeakPolarHBondContact CD2-OG1 3.31Å; T581-T585 WeakPolarHBondContact O-CB 3.46Å; T581-T585 PolarHBondContact O-N 2.61Å; T581-T585 VanDerWaalsContact O-N 3.14Å; T581-T585 PolarHBondContact O-OG1 3.42Å; A582-T585 PolarHBondContact O-N 2.73Å; T585-L587 VanDerWaalsContact C-N 3.27Å; T585-L587 PolarHBondContact O-N 3.4Å; T585-A588 WeakPolarHBondContact O-CB 3.41Å; T585-A588 PolarHBondContact O-N 3.47Å; T585-A588 VanDerWaalsContact O-N 3.14Å; T585-L589 HydrophobicContact CG2-CD1 4.22Å; T585-L589 HydrophobicContact CG2-CG 4.28Å; T585-L589 WeakPolarHBondContact O-CG 3.36Å; T585-L589 PolarHBondContact O-N 2.8Å
586W98.9Very high98Very high12 Ų1224.9 Ų24.95%0.04512%0.121CC..Hα-helixtrans-59.7-36.1176.1-177-110.1000112.8W373 F374 K377 I378 L388 A582 E583 E584 L589 M590 M593W373-W586 HydrophobicContact CH2-CB 4.28Å; W373-W586 HydrophobicContact CH2-CG 4.36Å; W373-W586 HydrophobicContact CZ3-CB 3.73Å; W373-W586 HydrophobicContact CZ3-CD2 4.35Å; W373-W586 AromaticContact CZ3-CG 3.88Å; W373-W586 HydrophobicContact CZ3-CG 3.88Å; F374-W586 HydrophobicContact CB-CE3 4.43Å; F374-W586 HydrophobicContact CB-CZ3 4.37Å; F374-W586 HydrophobicContact CD1-CB 4.47Å; F374-W586 AromaticContact CD1-CE3 3.72Å; F374-W586 HydrophobicContact CD1-CE3 3.72Å; F374-W586 HydrophobicContact CD1-CZ3 4.46Å; F374-W586 HydrophobicContact CE1-CB 4.27Å; F374-W586 HydrophobicContact CE1-CE3 4.4Å; F374-W586 HydrophobicContact CG-CE3 4.31Å; K377-W586 HydrophobicContact CG-CD2 3.88Å; K377-W586 HydrophobicContact CG-CG 4.16Å; K377-W586 HydrophobicContact CG-CZ2 3.95Å; I378-W586 HydrophobicContact CD1-CH2 4.37Å; I378-W586 HydrophobicContact CD1-CZ3 4.47Å; I378-W586 HydrophobicContact CG1-CH2 3.52Å; I378-W586 HydrophobicContact CG1-CZ2 4.46Å; I378-W586 HydrophobicContact CG1-CZ3 4.01Å; L388-W586 HydrophobicContact CD1-CH2 4.28Å; L388-W586 HydrophobicContact CD1-CZ2 4.26Å; L388-W586 HydrophobicContact CD2-CZ2 4.27Å; A582-W586 WeakPolarHBondContact O-CB 3.29Å; A582-W586 PolarHBondContact O-N 3.07Å; E583-W586 WeakPolarHBondContact O-CB 3.2Å; E583-W586 PolarHBondContact O-N 3.42Å; E584-W586 VanDerWaalsContact C-N 3.26Å; E584-W586 PolarHBondContact O-N 2.91Å; W586-L589 HydrophobicContact CE3-CB 4.41Å; W586-L589 HydrophobicContact CE3-CD1 4.15Å; W586-L589 PolarHBondContact O-N 2.91Å; W586-M590 HydrophobicContact CD2-CG 4.25Å; W586-M590 HydrophobicContact CG-CG 4.5Å; W586-M590 HydrophobicContact CH2-SD 4.17Å; W586-M590 HydrophobicContact CZ2-CG 3.98Å; W586-M590 HydrophobicContact CZ2-SD 3.56Å; W586-M590 VanDerWaalsContact CZ2-SD 3.56Å; W586-M590 WeakPolarHBondContact O-CB 3.43Å; W586-M590 WeakPolarHBondContact O-CG 3.3Å; W586-M590 PolarHBondContact O-N 3.42Å; W586-M593 HydrophobicContact CH2-CE 3.79Å; W586-M593 HydrophobicContact CZ2-CE 4.41Å; W586-M593 HydrophobicContact CZ3-CE 4.02Å
587L98.8Very high98.3Very high57 Ų5720.8 Ų20.830%0.29810%0.101SC..Hα-helixtrans-63.9-42.6175.3-60.5-178.7000111.6D521 L525 E584 T585 M590 A591D521-L587 HydrophobicContact CB-CB 4.31Å; D521-L587 VanDerWaalsContact O-CD1 3.3Å; D521-L587 WeakPolarHBondContact O-CD1 3.47Å; L525-L587 HydrophobicContact CB-CD1 3.87Å; L525-L587 HydrophobicContact CD2-CD1 4.38Å; E584-L587 WeakPolarHBondContact O-CB 3.12Å; E584-L587 PolarHBondContact O-N 2.58Å; T585-L587 VanDerWaalsContact C-N 3.27Å; T585-L587 PolarHBondContact O-N 3.4Å; L587-M590 PolarHBondContact O-N 3.02Å; L587-A591 PolarHBondContact O-N 3.12Å; L587-A591 VanDerWaalsContact O-N 3.1Å
588A98.9Very high98.4Very high0 Ų024.9 Ų24.90%012%0.119CC..Hα-helixtrans-64.4-45.8173.900000111.9A518 L522 F561 T585 M590 A591 L592A518-A588 HydrophobicContact CB-CB 3.99Å; A518-A588 WeakPolarHBondContact O-CB 3.48Å; L522-A588 HydrophobicContact CB-CB 4.14Å; L522-A588 HydrophobicContact CD1-CB 4.15Å; F561-A588 HydrophobicContact CE1-CB 3.77Å; F561-A588 HydrophobicContact CZ-CB 3.63Å; T585-A588 WeakPolarHBondContact O-CB 3.41Å; T585-A588 PolarHBondContact O-N 3.47Å; T585-A588 VanDerWaalsContact O-N 3.14Å; A588-M590 VanDerWaalsContact C-N 3.33Å; A588-M590 PolarHBondContact O-N 2.87Å; A588-A591 WeakPolarHBondContact O-CB 3.26Å; A588-A591 PolarHBondContact O-N 3.16Å; A588-A591 VanDerWaalsContact O-N 3.13Å; A588-L592 WeakPolarHBondContact O-CG 3.42Å; A588-L592 PolarHBondContact O-N 3.13Å
589L98.9Very high98.4Very high0 Ų028.1 Ų28.10%014%0.136CC..Hα-helixtrans-57.8-45.8176.5-71.6173.5000111.2I356 F374 I485 I487 F561 T585 W586 A591 L592 M593I356-L589 HydrophobicContact CD1-CD2 4.49Å; F374-L589 HydrophobicContact CD1-CD1 4.14Å; F374-L589 HydrophobicContact CD2-CD1 4.06Å; F374-L589 HydrophobicContact CE1-CD1 3.89Å; F374-L589 HydrophobicContact CE2-CD1 3.81Å; F374-L589 HydrophobicContact CG-CD1 4.26Å; F374-L589 HydrophobicContact CZ-CD1 3.73Å; I485-L589 HydrophobicContact CD1-CD2 4.11Å; I485-L589 HydrophobicContact CG2-CD2 3.77Å; I487-L589 HydrophobicContact CD1-CD1 4.43Å; I487-L589 HydrophobicContact CD1-CD2 4.42Å; F561-L589 HydrophobicContact CE2-CD2 4.07Å; T585-L589 HydrophobicContact CG2-CD1 4.22Å; T585-L589 HydrophobicContact CG2-CG 4.28Å; T585-L589 WeakPolarHBondContact O-CG 3.36Å; T585-L589 PolarHBondContact O-N 2.8Å; W586-L589 HydrophobicContact CE3-CB 4.41Å; W586-L589 HydrophobicContact CE3-CD1 4.15Å; W586-L589 PolarHBondContact O-N 2.91Å; L589-A591 VanDerWaalsContact C-N 3.3Å; L589-A591 PolarHBondContact O-N 3.33Å; L589-L592 PolarHBondContact O-N 2.03Å; L589-L592 VanDerWaalsContact O-N 3.16Å; L589-M593 HydrophobicContact CB-CE 4.33Å; L589-M593 WeakPolarHBondContact O-CB 3.22Å; L589-M593 VanDerWaalsContact O-CG 3.25Å; L589-M593 WeakPolarHBondContact O-CG 3.5Å; L589-M593 PolarHBondContact O-N 2.94Å
590M98.8Very high97.6Very high27 Ų2729.8 Ų29.813%0.13315%0.15CC..Hα-helixtrans-58.9-39.9176-78.2-59.8-60.100112.2A387 L388 I391 W586 L587 A588 M593 D594A387-M590 HydrophobicContact CB-CE 3.93Å; L388-M590 HydrophobicContact CB-CE 3.94Å; L388-M590 HydrophobicContact CB-SD 4.28Å; L388-M590 HydrophobicContact CD1-SD 4.17Å; I391-M590 HydrophobicContact CD1-CE 4.09Å; W586-M590 HydrophobicContact CD2-CG 4.25Å; W586-M590 HydrophobicContact CG-CG 4.5Å; W586-M590 HydrophobicContact CH2-SD 4.17Å; W586-M590 HydrophobicContact CZ2-CG 3.98Å; W586-M590 HydrophobicContact CZ2-SD 3.56Å; W586-M590 VanDerWaalsContact CZ2-SD 3.56Å; W586-M590 WeakPolarHBondContact O-CB 3.43Å; W586-M590 WeakPolarHBondContact O-CG 3.3Å; W586-M590 PolarHBondContact O-N 3.42Å; L587-M590 PolarHBondContact O-N 3.02Å; A588-M590 VanDerWaalsContact C-N 3.33Å; A588-M590 PolarHBondContact O-N 2.87Å; M590-M593 HydrophobicContact CG-CE 4.31Å; M590-M593 PolarHBondContact O-N 3.11Å; M590-M593 HydrophobicContact SD-CE 3.53Å; M590-M593 VanDerWaalsContact SD-CE 3.53Å; M590-D594 WeakPolarHBondContact O-CB 3.46Å; M590-D594 PolarHBondContact O-N 3.27Å
591A98.8Very high96.4Very high5 Ų533.7 Ų33.74%0.04116%0.162CC..Hα-helixtrans-62.7-43175.100000112.5A518 D521 L587 A588 L589 H595A518-A591 HydrophobicContact CB-CB 4.12Å; D521-A591 WeakPolarHBondContact OD2-CB 3.15Å; L587-A591 PolarHBondContact O-N 3.12Å; L587-A591 VanDerWaalsContact O-N 3.1Å; A588-A591 WeakPolarHBondContact O-CB 3.26Å; A588-A591 PolarHBondContact O-N 3.16Å; A588-A591 VanDerWaalsContact O-N 3.13Å; L589-A591 VanDerWaalsContact C-N 3.3Å; L589-A591 PolarHBondContact O-N 3.33Å; A591-H595 WeakPolarHBondContact O-CB 3.48Å; A591-H595 PolarHBondContact O-N 2.94Å; A591-H595 VanDerWaalsContact O-N 3.13Å
592L98.8Very high96.3Very high2 Ų235.4 Ų35.41%0.0117%0.17CC..Hα-helixtrans-65.9-45.3177-60.7-177.7000111.7I485 L514 A518 Y559 F561 A588 L589 T596I485-L592 HydrophobicContact CD1-CB 4.49Å; I485-L592 HydrophobicContact CD1-CD1 4.28Å; I485-L592 HydrophobicContact CG1-CD1 4.14Å; L514-L592 HydrophobicContact CD1-CD2 4.07Å; L514-L592 HydrophobicContact CD2-CD2 3.83Å; L514-L592 HydrophobicContact CG-CD2 3.59Å; A518-L592 HydrophobicContact CB-CD2 4Å; A518-L592 HydrophobicContact CB-CG 4.3Å; Y559-L592 HydrophobicContact CD2-CD1 4.09Å; Y559-L592 HydrophobicContact CD2-CD2 4.07Å; Y559-L592 HydrophobicContact CE2-CD2 3.88Å; Y559-L592 HydrophobicContact CG-CD1 4.16Å; Y559-L592 HydrophobicContact CG-CD2 4.48Å; F561-L592 HydrophobicContact CE2-CD1 3.84Å; F561-L592 HydrophobicContact CZ-CD1 4.17Å; A588-L592 WeakPolarHBondContact O-CG 3.42Å; A588-L592 PolarHBondContact O-N 3.13Å; L589-L592 PolarHBondContact O-N 2.03Å; L589-L592 VanDerWaalsContact O-N 3.16Å; L592-T596 WeakPolarHBondContact O-CB 3.4Å; L592-T596 PolarHBondContact O-N 2.92Å; L592-T596 PolarHBondContact O-OG1 2.78Å
593M98.8Very high96.2Very high0 Ų037.2 Ų37.20%018%0.179CC..Hα-helixtrans-68.1-42.8-178.7-66.4-169.3-67.800112.2I354 I356 I391 I397 W586 L589 M590 T596 Y597I354-M593 HydrophobicContact CD1-CB 3.86Å; I354-M593 HydrophobicContact CD1-CG 3.77Å; I354-M593 HydrophobicContact CD1-SD 4.22Å; I354-M593 HydrophobicContact CG2-CG 4.16Å; I354-M593 HydrophobicContact CG2-SD 4.39Å; I356-M593 HydrophobicContact CD1-SD 4.38Å; I391-M593 HydrophobicContact CD1-CB 3.84Å; I397-M593 HydrophobicContact CD1-SD 3.8Å; I397-M593 HydrophobicContact CG1-SD 4.5Å; W586-M593 HydrophobicContact CH2-CE 3.79Å; W586-M593 HydrophobicContact CZ2-CE 4.41Å; W586-M593 HydrophobicContact CZ3-CE 4.02Å; L589-M593 HydrophobicContact CB-CE 4.33Å; L589-M593 WeakPolarHBondContact O-CB 3.22Å; L589-M593 VanDerWaalsContact O-CG 3.25Å; L589-M593 WeakPolarHBondContact O-CG 3.5Å; L589-M593 PolarHBondContact O-N 2.94Å; M590-M593 HydrophobicContact CG-CE 4.31Å; M590-M593 PolarHBondContact O-N 3.11Å; M590-M593 HydrophobicContact SD-CE 3.53Å; M590-M593 VanDerWaalsContact SD-CE 3.53Å; M593-T596 WeakPolarHBondContact O-CB 2.95Å; M593-T596 PolarHBondContact O-N 3Å; M593-Y597 WeakPolarHBondContact O-CB 3.41Å; M593-Y597 PolarHBondContact O-N 3.03Å
594D98.6Very high96Very high33 Ų3335.9 Ų35.918%0.17617%0.173CC..Hα-helixtrans-64.4-41.1177178.862000111.6I391 M590 Y597 K598I391-D594 HydrophobicContact CD1-CB 4.34Å; M590-D594 WeakPolarHBondContact O-CB 3.46Å; M590-D594 PolarHBondContact O-N 3.27Å; D594-Y597 PolarHBondContact O-N 2.78Å; D594-K598 WeakPolarHBondContact O-CB 3.45Å; D594-K598 WeakPolarHBondContact O-CG 3.47Å; D594-K598 PolarHBondContact O-N 3.37Å; D594-K598 WeakPolarHBondContact OD1-CE 3.39Å; D594-K598 IonicContact OD1-NZ 2.87Å; D594-K598 PolarHBondContact OD1-NZ 2.8Å; D594-K598 WeakPolarHBondContact OD2-CE 3.21Å; D594-K598 IonicContact OD2-NZ 3.47Å; D594-K598 PolarHBondContact OD2-NZ 2.9Å
595H98.6Very high95.9Very high44 Ų4438.1 Ų38.120%0.20418%0.183CC..Hα-helixtrans-63-43.1173.7-172.994.4000111.6E510 L514 Y557 A591 Y597 K598 N599E510-H595 IonicContact OE1-CD2 3.65Å; E510-H595 IonicContact OE1-CE1 3.33Å; E510-H595 IonicContact OE1-NE2 2.75Å; E510-H595 PolarHBondContact OE1-NE2 3.31Å; L514-H595 HydrophobicContact CD1-CB 3.56Å; L514-H595 HydrophobicContact CD2-CB 3.91Å; L514-H595 HydrophobicContact CG-CB 4.4Å; Y557-H595 AromaticContact CE1-CD2 3.49Å; Y557-H595 VanDerWaalsContact CE1-CD2 3.49Å; Y557-H595 WeakPolarHBondContact CE1-CD2 3.46Å; Y557-H595 AromaticContact CE1-NE2 3.64Å; Y557-H595 AromaticContact CZ-CD2 3.34Å; Y557-H595 AromaticContact CZ-NE2 3.57Å; Y557-H595 PolarHBondContact OH-CD2 3.01Å; Y557-H595 PolarHBondContact OH-NE2 3.23Å; A591-H595 WeakPolarHBondContact O-CB 3.48Å; A591-H595 PolarHBondContact O-N 2.94Å; A591-H595 VanDerWaalsContact O-N 3.13Å; H595-Y597 PolarHBondContact O-N 3.4Å; H595-K598 PolarHBondContact O-N 3.48Å; H595-N599 PolarHBondContact CE1-ND2 3.45Å; H595-N599 PolarHBondContact NE2-ND2 2.8Å; H595-N599 WeakPolarHBondContact O-CB 3.39Å; H595-N599 PolarHBondContact O-N 3.25Å; H595-N599 PolarHBondContact O-ND2 2.82Å
596T98.2Very high95.7Very high0 Ų040.4 Ų40.40%020%0.195CC..Hα-helixtrans-60.2-45.9176.8-58.20000111.5I354 M395 K482 A483 Y557 L592 M593 K598 N599I354-T596 HydrophobicContact CG1-CG2 4.3Å; M395-T596 HydrophobicContact CE-CG2 3.68Å; M395-T596 HydrophobicContact SD-CG2 4.23Å; K482-T596 HydrophobicContact CB-CG2 3.64Å; A483-T596 HydrophobicContact CB-CG2 3.95Å; Y557-T596 HydrophobicContact CD2-CG2 3.83Å; Y557-T596 VanDerWaalsContact CD2-OG1 3.27Å; Y557-T596 WeakPolarHBondContact CD2-OG1 3.35Å; Y557-T596 HydrophobicContact CE2-CG2 4.25Å; L592-T596 WeakPolarHBondContact O-CB 3.4Å; L592-T596 PolarHBondContact O-N 2.92Å; L592-T596 PolarHBondContact O-OG1 2.78Å; M593-T596 WeakPolarHBondContact O-CB 2.95Å; M593-T596 PolarHBondContact O-N 3Å; T596-K598 VanDerWaalsContact C-N 3.33Å; T596-K598 PolarHBondContact O-N 2.8Å; T596-N599 CarbonylContact O-C 3.55Å; T596-N599 PolarHBondContact O-N 2.92Å
597Y97.8Very high95.5Very high73 Ų7342.3 Ų42.329%0.28621%0.205SC..Hα-helixtrans-60.3-40.8177.1162.2-115.5000112.6A390 I391 N394 M593 D594 H595 N599A390-Y597 HydrophobicContact CB-CE1 3.98Å; I391-Y597 HydrophobicContact CG1-CD1 4.36Å; I391-Y597 HydrophobicContact CG1-CG 4.17Å; N394-Y597 HydrophobicContact CB-CD2 3.99Å; N394-Y597 HydrophobicContact CB-CE2 3.65Å; N394-Y597 WeakPolarHBondContact ND2-CE2 3.28Å; M593-Y597 WeakPolarHBondContact O-CB 3.41Å; M593-Y597 PolarHBondContact O-N 3.03Å; D594-Y597 PolarHBondContact O-N 2.78Å; H595-Y597 PolarHBondContact O-N 3.4Å; Y597-N599 VanDerWaalsContact C-N 3.31Å; Y597-N599 PolarHBondContact O-N 3.21Å
598K97.8Very high95.2Very high125 Ų12541.3 Ų41.354%0.54320%0.198SC..Hα-helixtrans-76.6-16.9-179.9-72.2170.1179.8164.40113.8D594 H595 T596 P600D594-K598 WeakPolarHBondContact O-CB 3.45Å; D594-K598 WeakPolarHBondContact O-CG 3.47Å; D594-K598 PolarHBondContact O-N 3.37Å; D594-K598 WeakPolarHBondContact OD1-CE 3.39Å; D594-K598 IonicContact OD1-NZ 2.87Å; D594-K598 PolarHBondContact OD1-NZ 2.8Å; D594-K598 WeakPolarHBondContact OD2-CE 3.21Å; D594-K598 IonicContact OD2-NZ 3.47Å; D594-K598 PolarHBondContact OD2-NZ 2.9Å; H595-K598 PolarHBondContact O-N 3.48Å; T596-K598 VanDerWaalsContact C-N 3.33Å; T596-K598 PolarHBondContact O-N 2.8Å; K598-P600 VanDerWaalsContact C-CD 3.43Å
599N96.9Very high95Very high68 Ų6844.5 Ų44.536%0.36421%0.213SC..SBendtrans-129.261.7-177.5-58.6-83000111.5Y557 H595 T596 Y597 Y601Y557-N599 VanDerWaalsContact OH-CB 3.24Å; Y557-N599 WeakPolarHBondContact OH-CB 3.26Å; H595-N599 PolarHBondContact CE1-ND2 3.45Å; H595-N599 PolarHBondContact NE2-ND2 2.8Å; H595-N599 WeakPolarHBondContact O-CB 3.39Å; H595-N599 PolarHBondContact O-N 3.25Å; H595-N599 PolarHBondContact O-ND2 2.82Å; T596-N599 CarbonylContact O-C 3.55Å; T596-N599 PolarHBondContact O-N 2.92Å; Y597-N599 VanDerWaalsContact C-N 3.31Å; Y597-N599 PolarHBondContact O-N 3.21Å; N599-Y601 WeakPolarHBondContact O-CD1 3.37Å; N599-Y601 PolarHBondContact O-N 2.89Å; N599-Y601 VanDerWaalsContact O-N 3.12Å
600P78.8Confident94.6Very high88 Ų8848.2 Ų48.257%0.57123%0.231SC*.  trans-74.8103.6179.931.1-32.1000109.6K598K598-P600 VanDerWaalsContact C-CD 3.43Å
601Y73.7Confident94.2Very high113 Ų11350.1 Ų50.144%0.44324%0.24SC..  trans-97.60173.852-105.8000113K482 K556 Y557 N599K482-Y601 WeakPolarHBondContact CD-O 3.33Å; K482-Y601 WeakPolarHBondContact CE-O 3.46Å; K482-Y601 PolarHBondContact NZ-O 2.97Å; K482-Y601 PolarHBondContact O-OH 3.29Å; K556-Y601 VanDerWaalsContact CA-OH 3.28Å; K556-Y601 WeakPolarHBondContact CA-OH 3.5Å; K556-Y601 HydrophobicContact CB-CE1 3.82Å; K556-Y601 HydrophobicContact CB-CE2 3.78Å; K556-Y601 WeakPolarHBondContact CB-OH 3.35Å; K556-Y601 HydrophobicContact CD-CD1 3.87Å; K556-Y601 HydrophobicContact CD-CE1 3.42Å; K556-Y601 VanDerWaalsContact CD-CE1 3.42Å; K556-Y601 HydrophobicContact CG-CD1 4.46Å; K556-Y601 HydrophobicContact CG-CE1 3.54Å; K556-Y601 HydrophobicContact CG-CE2 4.43Å; K556-Y601 PolarHBondContact N-OH 3.22Å; Y557-Y601 AromaticContact CD2-CE1 3.6Å; Y557-Y601 HydrophobicContact CD2-CE1 3.6Å; Y557-Y601 AromaticContact CD2-CZ 3.76Å; Y557-Y601 WeakPolarHBondContact CD2-OH 3.38Å; Y557-Y601 HydrophobicContact CE1-CE1 4.22Å; Y557-Y601 HydrophobicContact CE2-CD1 4.03Å; Y557-Y601 AromaticContact CE2-CE1 3.16Å; Y557-Y601 HydrophobicContact CE2-CE1 3.16Å; Y557-Y601 AromaticContact CE2-CZ 3.82Å; Y557-Y601 HydrophobicContact CG-CE1 4.3Å; Y557-Y601 AromaticContact CZ-CE1 3.47Å; Y557-Y601 VanDerWaalsContact CZ-CE1 3.47Å; Y557-Y601 PolarHBondContact N-OH 3.34Å; N599-Y601 WeakPolarHBondContact O-CD1 3.37Å; N599-Y601 PolarHBondContact O-N 2.89Å; N599-Y601 VanDerWaalsContact O-N 3.12Å

Retrieved 601 of 601 residues in 681.9 ms (Link to these results)