A0A087Y9X5_POEFO Loading...

MFSD2 lysolipid transporter A, lysophospholipid b

Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid.

AlphaFold DB , UniProt , Accession A0A087Y9X5, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 524 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	31.8	Very low	27.9	Very low	247 Å²	247	148.1 Å²	148.1	100%	1.217	85%	0.846	S	S	*	*				0	128.4	0	-101.4	173.4	167.5	0	0	108.3
2	A	31.2	Very low	28.1	Very low	96 Å²	96	148.5 Å²	148.5	79%	0.793	84%	0.843	S	S	*	*			trans	56.2	108.5	154	0	0	0	0	0	121.6
3	K	28.3	Very low	28.4	Very low	216 Å²	216	143.7 Å²	143.7	94%	0.939	83%	0.833	S	S	*	*				55.7	127.7	103.3	-138.5	179.7	-171.4	-174.8	0	118.8
4	G	27.5	Very low	28.4	Very low	77 Å²	77	141.5 Å²	141.5	79%	0.794	83%	0.83	S	S	*	*			trans	163.8	112.2	156	0	0	0	0	0	114.8
5	E	29.8	Very low	28.5	Very low	203 Å²	203	143.6 Å²	143.6	95%	0.949	84%	0.835	S	S	*	*			trans	-70.8	161.5	179.8	-64.2	155.9	129.7	0	0	114
6	G	26	Very low	28.9	Very low	75 Å²	75	145.3 Å²	145.3	77%	0.773	84%	0.839	S	S	*	*			trans	155.8	103.4	154.3	0	0	0	0	0	118
7	A	27.3	Very low	29.1	Very low	105 Å²	105	146.4 Å²	146.4	87%	0.868	84%	0.841	S	S	*	*			trans	75.9	120.8	143.3	0	0	0	0	0	122.1
8	E	26.7	Very low	29.3	Very low	173 Å²	173	148.9 Å²	148.9	81%	0.808	84%	0.841	S	S	*	*			trans	-12.6	150.4	149	-54.7	178.6	146.1	0	0	116.9
9	Q	25.8	Very low	29.5	Very low	139 Å²	139	146.3 Å²	146.3	65%	0.65	83%	0.833	S	S	*	*			cis	-179.2	162.1	49.3	-150.5	161.9	2.9	0	0	112.2
10	Y	25	Very low	30	Very low	186 Å²	186	145 Å²	145	73%	0.729	83%	0.828	S	S	*	*			trans	87.5	89.9	164.5	-68.9	-78.6	0	0	0	119.8
11	S	27.2	Very low	30.3	Very low	112 Å²	112	139.9 Å²	139.9	78%	0.783	80%	0.801	S	S	*	*			trans	-122.3	112.9	141.2	-173.9	0	0	0	0	109	A13	S11-A13 PolarHBondContact O-N 3.06Å
12	N	30.4	Very low	30.5	Very low	153 Å²	153	131.7 Å²	131.7	82%	0.818	77%	0.768	S	S	*	*			trans	-70.6	88.8	172.2	-76.2	-28.5	0	0	0	109.3
13	A	31.9	Very low	30.8	Very low	86 Å²	86	131.5 Å²	131.5	71%	0.711	75%	0.754	S	S	*	*			trans	-153.8	61.4	172.3	0	0	0	0	0	111.4	S11	S11-A13 PolarHBondContact O-N 3.06Å
14	S	28.5	Very low	31.5	Very low	113 Å²	113	125.6 Å²	125.6	79%	0.79	74%	0.736	S	S	*	*			trans	-152.5	14.7	166.9	75.8	0	0	0	0	116.3
15	L	30.4	Very low	32.3	Very low	173 Å²	173	127 Å²	127	91%	0.906	72%	0.723	S	S	*	*	S	Bend	trans	-96.3	9.8	178.4	-81.6	169.8	0	0	0	115.3
16	L	34.2	Very low	32.5	Very low	171 Å²	171	123.8 Å²	123.8	90%	0.895	71%	0.706	S	S	*	*	S	Bend	trans	-116.8	31.5	-178.4	-98	164.6	0	0	0	114
17	N	32.8	Very low	33.1	Very low	163 Å²	163	125.7 Å²	125.7	87%	0.872	70%	0.698	S	S	*	*			trans	-147	51.5	169.5	-120.9	-6.8	0	0	0	111.4	S19	N17-S19 PolarHBondContact O-N 3.29Å
18	K	32.9	Very low	33.5	Very low	192 Å²	192	124.4 Å²	124.4	84%	0.835	68%	0.683	S	S	*	*			trans	-83.8	104.6	163.8	-155	171	-171.5	176	0	106.8	V20	K18-V20 PolarHBondContact O-N 3.48Å
19	S	33	Very low	33.7	Very low	99 Å²	99	124.8 Å²	124.8	69%	0.692	68%	0.677	S	S	*	*			trans	-20.9	102.4	168.9	43.8	0	0	0	0	113	N17 S21	N17-S19 PolarHBondContact O-N 3.29Å; S19-S21 WeakPolarHBondContact O-CA 3.45Å; S19-S21 PolarHBondContact O-N 2.95Å
20	V	38.9	Very low	33.9	Very low	121 Å²	121	125.7 Å²	125.7	73%	0.733	68%	0.679	S	S	*	*			trans	-56.8	99.1	158.5	173.8	0	0	0	0	104.8	K18 S22	K18-V20 PolarHBondContact O-N 3.48Å; V20-S22 PolarHBondContact O-N 3.35Å
21	S	37.1	Very low	34.2	Very low	37 Å²	37	123.1 Å²	123.1	26%	0.259	67%	0.673	S	S	.	*			trans	-59.4	138.6	-156.9	169.6	0	0	0	0	110.2	S19 D23 V24 I25	S19-S21 WeakPolarHBondContact O-CA 3.45Å; S19-S21 PolarHBondContact O-N 2.95Å; S21-D23 PolarHBondContact O-N 3.42Å; S21-D23 VanDerWaalsContact OG-CB 3.23Å; S21-D23 WeakPolarHBondContact OG-CB 3.4Å; S21-D23 PolarHBondContact OG-N 3.34Å; S21-D23 PolarHBondContact OG-OD2 3.21Å; S21-V24 PolarHBondContact O-N 3.38Å; S21-I25 PolarHBondContact O-N 3.32Å
22	S	36.3	Very low	34.6	Very low	76 Å²	76	123.3 Å²	123.3	53%	0.531	66%	0.661	S	S	.	*	H	α-helix	trans	-52.8	-18.9	167	81.7	0	0	0	0	112.2	V20 K26	V20-S22 PolarHBondContact O-N 3.35Å; S22-K26 WeakPolarHBondContact O-CB 3.42Å; S22-K26 VanDerWaalsContact O-CG 3.3Å; S22-K26 WeakPolarHBondContact O-CG 3.46Å; S22-K26 PolarHBondContact O-N 3.11Å
23	D	37.4	Very low	34.8	Very low	92 Å²	92	123.6 Å²	123.6	49%	0.492	66%	0.658	S	S	.	*	H	α-helix	trans	-77	-28.1	172.6	-60.8	-42.4	0	0	0	113.7	S21 L27	S21-D23 PolarHBondContact O-N 3.42Å; S21-D23 VanDerWaalsContact OG-CB 3.23Å; S21-D23 WeakPolarHBondContact OG-CB 3.4Å; S21-D23 PolarHBondContact OG-N 3.34Å; S21-D23 PolarHBondContact OG-OD2 3.21Å; D23-L27 WeakPolarHBondContact O-CA 3.45Å; D23-L27 WeakPolarHBondContact O-CB 3.25Å; D23-L27 WeakPolarHBondContact O-CD1 3.29Å; D23-L27 PolarHBondContact O-N 3.23Å
24	V	43.3	Very low	35.2	Very low	92 Å²	92	129.6 Å²	129.6	56%	0.558	66%	0.662	S	S	*	*	H	α-helix	trans	-73.2	-40.2	171.7	178.2	0	0	0	0	109.9	S21 L27 S28	S21-V24 PolarHBondContact O-N 3.38Å; V24-L27 PolarHBondContact O-N 3.14Å; V24-S28 WeakPolarHBondContact O-CB 3.4Å; V24-S28 PolarHBondContact O-N 3.29Å
25	I	44.1	Very low	36.4	Very low	105 Å²	105	127.9 Å²	127.9	54%	0.538	65%	0.647	S	S	.	*	H	α-helix	trans	-69.8	-38.1	174.2	-60.4	174.4	0	0	0	110.7	S21 R29	S21-I25 PolarHBondContact O-N 3.32Å; I25-R29 WeakPolarHBondContact O-CB 3.44Å; I25-R29 PolarHBondContact O-N 2.92Å
26	K	34.4	Very low	37.8	Very low	136 Å²	136	128.2 Å²	128.2	59%	0.591	64%	0.636	S	S	*	*	H	α-helix	trans	-70.2	-36.3	171.9	-85	174.8	176.3	170.6	0	112.6	S22 K30	S22-K26 WeakPolarHBondContact O-CB 3.42Å; S22-K26 VanDerWaalsContact O-CG 3.3Å; S22-K26 WeakPolarHBondContact O-CG 3.46Å; S22-K26 PolarHBondContact O-N 3.11Å; K26-K30 WeakPolarHBondContact O-CB 3.34Å; K26-K30 PolarHBondContact O-N 3.22Å
27	L	36.7	Very low	39.3	Very low	116 Å²	116	121.4 Å²	121.4	61%	0.607	60%	0.6	S	S	*	*	H	α-helix	trans	-66.8	-44.3	173.1	-106.2	90.4	0	0	0	110	D23 V24 K30 H31	D23-L27 WeakPolarHBondContact O-CA 3.45Å; D23-L27 WeakPolarHBondContact O-CB 3.25Å; D23-L27 WeakPolarHBondContact O-CD1 3.29Å; D23-L27 PolarHBondContact O-N 3.23Å; V24-L27 PolarHBondContact O-N 3.14Å; L27-K30 CarbonylContact O-C 3.52Å; L27-K30 PolarHBondContact O-N 3.44Å; L27-K30 VanDerWaalsContact O-N 3.15Å; L27-H31 WeakPolarHBondContact O-CB 3.49Å; L27-H31 PolarHBondContact O-N 3.05Å
28	S	35.8	Very low	41.7	Very low	77 Å²	77	116.8 Å²	116.8	54%	0.538	58%	0.581	S	S	.	*	H	α-helix	trans	-60	-46.5	174.9	-167.6	0	0	0	0	110.8	V24 K30 H31 E32	V24-S28 WeakPolarHBondContact O-CB 3.4Å; V24-S28 PolarHBondContact O-N 3.29Å; S28-K30 VanDerWaalsContact C-N 3.34Å; S28-K30 PolarHBondContact O-N 3.49Å; S28-H31 PolarHBondContact O-N 3.46Å; S28-E32 WeakPolarHBondContact O-CB 3.36Å; S28-E32 PolarHBondContact O-N 3.07Å
29	R	31.9	Very low	44.1	Very low	181 Å²	181	112.9 Å²	112.9	68%	0.683	57%	0.568	S	S	*	*	H	α-helix	trans	-64	-34.4	173.1	-107	-179.9	178.6	172.9	1.3	113.4	I25 H33	I25-R29 WeakPolarHBondContact O-CB 3.44Å; I25-R29 PolarHBondContact O-N 2.92Å; R29-H33 WeakPolarHBondContact O-CB 3.36Å; R29-H33 PolarHBondContact O-N 3.19Å; R29-H33 VanDerWaalsContact O-N 3.13Å
30	K	29	Very low	46.5	Very low	158 Å²	158	111.7 Å²	111.7	69%	0.687	56%	0.559	S	S	*	*	H	α-helix	trans	-77.1	-26.3	178.6	-164.2	176.2	-173.3	-178	0	111.7	K26 L27 S28	K26-K30 WeakPolarHBondContact O-CB 3.34Å; K26-K30 PolarHBondContact O-N 3.22Å; L27-K30 CarbonylContact O-C 3.52Å; L27-K30 PolarHBondContact O-N 3.44Å; L27-K30 VanDerWaalsContact O-N 3.15Å; S28-K30 VanDerWaalsContact C-N 3.34Å; S28-K30 PolarHBondContact O-N 3.49Å
31	H	32.3	Very low	48.7	Very low	132 Å²	132	109.2 Å²	109.2	61%	0.611	54%	0.541	S	S	*	.	H	α-helix	trans	-77.3	-39.4	171.4	-128	-54.3	0	0	0	111.6	L27 S28 H33 R34	L27-H31 WeakPolarHBondContact O-CB 3.49Å; L27-H31 PolarHBondContact O-N 3.05Å; S28-H31 PolarHBondContact O-N 3.46Å; H31-H33 VanDerWaalsContact C-N 3.27Å; H31-H33 PolarHBondContact O-N 3.01Å; H31-R34 PolarHBondContact O-N 3.26Å
32	E	35.3	Very low	51.1	Low	116 Å²	116	108.2 Å²	108.2	54%	0.542	53%	0.532	S	S	.	.	H	α-helix	trans	-65.5	-29.9	175.3	-159.2	-176.8	177.1	0	0	112.2	S28 R34 T35	S28-E32 WeakPolarHBondContact O-CB 3.36Å; S28-E32 PolarHBondContact O-N 3.07Å; E32-R34 VanDerWaalsContact C-N 3.3Å; E32-R34 PolarHBondContact O-N 3.07Å; E32-T35 PolarHBondContact O-OG1 2.95Å
33	H	33.8	Very low	53.5	Low	159 Å²	159	108.1 Å²	108.1	74%	0.736	53%	0.525	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.9	-10.3	176.6	-137.4	-63.9	0	0	0	114.1	R29 H31	R29-H33 WeakPolarHBondContact O-CB 3.36Å; R29-H33 PolarHBondContact O-N 3.19Å; R29-H33 VanDerWaalsContact O-N 3.13Å; H31-H33 VanDerWaalsContact C-N 3.27Å; H31-H33 PolarHBondContact O-N 3.01Å
34	R	41.4	Very low	55.9	Low	213 Å²	213	104.6 Å²	104.6	80%	0.804	51%	0.507	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.4	-4.3	-178	-98.2	-174.8	173.1	-174.1	-2	114.5	H31 E32	H31-R34 PolarHBondContact O-N 3.26Å; E32-R34 VanDerWaalsContact C-N 3.3Å; E32-R34 PolarHBondContact O-N 3.07Å
35	T	53.5	Low	58	Low	77 Å²	77	100.3 Å²	100.3	47%	0.472	48%	0.481	S	S	.	.	S	Bend	trans	-117.9	11.6	-174.4	29.2	0	0	0	0	114.7	E32	E32-T35 PolarHBondContact O-OG1 2.95Å
36	R	59.2	Low	60.2	Low	179 Å²	179	95.3 Å²	95.3	68%	0.675	46%	0.456	S	S	*	.	S	Bend	trans	-95.3	127.7	170.5	-69.2	-169.3	-175.2	177	4	110.9	S38	R36-S38 PolarHBondContact O-N 3.36Å
37	L	67.1	Low	62.8	Low	29 Å²	29	91 Å²	91	15%	0.152	44%	0.439	C	S	.	.	P	Polyproline II helix	trans	-67.8	126.8	177.1	-73.7	164.9	0	0	0	109.8	K42 I170 T171 E176	L37-K42 HydrophobicContact CB-CD 4.48Å; L37-K42 HydrophobicContact CB-CG 4.02Å; L37-I170 HydrophobicContact CD1-CG2 3.59Å; L37-I170 HydrophobicContact CD2-CG2 3.26Å; L37-I170 HydrophobicContact CG-CG2 4.02Å; L37-T171 HydrophobicContact CD1-CG2 3.73Å; L37-E176 HydrophobicContact CD1-CB 4.29Å
38	S	81.5	Confident	65.2	Low	66 Å²	66	85.5 Å²	85.5	46%	0.462	41%	0.41	S	S	.	.	P	Polyproline II helix	trans	-57.2	142.4	169.7	179.1	0	0	0	0	110.1	R36 C40 N41 K42	R36-S38 PolarHBondContact O-N 3.36Å; S38-C40 PolarHBondContact O-N 2.84Å; S38-C40 PolarHBondContact OG-N 2.53Å; S38-N41 PolarHBondContact O-N 3.34Å; S38-K42 PolarHBondContact O-N 2.91Å; S38-K42 VanDerWaalsContact O-N 3.09Å
39	I	83.2	Confident	67.6	Low	109 Å²	109	81.9 Å²	81.9	56%	0.559	39%	0.385	S	S	*	.	H	α-helix	trans	-54.7	-36.1	175.5	-61.9	170	0	0	0	110.3	K42 I43	I39-K42 PolarHBondContact O-N 3.17Å; I39-I43 HydrophobicContact CG2-CD1 3.85Å; I39-I43 HydrophobicContact CG2-CG1 4.4Å; I39-I43 WeakPolarHBondContact O-CG1 3.5Å; I39-I43 PolarHBondContact O-N 3.36Å
40	C	85.2	Confident	70.4	Confident	75 Å²	75	73.6 Å²	73.6	51%	0.507	36%	0.355	S	S	.	.	H	α-helix	trans	-59.5	-47.3	175.2	-171.5	0	0	0	0	111.7	S38 K42 I43 C44	S38-C40 PolarHBondContact O-N 2.84Å; S38-C40 PolarHBondContact OG-N 2.53Å; C40-K42 VanDerWaalsContact C-N 3.31Å; C40-K42 PolarHBondContact O-N 3.42Å; C40-I43 PolarHBondContact O-N 2.99Å; C40-C44 WeakPolarHBondContact O-CB 3.43Å; C40-C44 PolarHBondContact O-N 3.1Å; C40-C44 PolarHBondContact O-SG 3.36Å
41	N	84.4	Confident	73.4	Confident	68 Å²	68	66.1 Å²	66.1	36%	0.364	32%	0.323	S	S	.	.	H	α-helix	trans	-65.2	-36	179.1	-64.1	8.4	0	0	0	111.6	S38 Y45	S38-N41 PolarHBondContact O-N 3.34Å; N41-Y45 VanDerWaalsContact O-CB 3.31Å; N41-Y45 WeakPolarHBondContact O-CB 3.44Å; N41-Y45 PolarHBondContact O-N 3.29Å
42	K	86.3	Confident	76.2	Confident	16 Å²	16	62 Å²	62	7%	0.07	30%	0.302	C	S	.	.	H	α-helix	trans	-64.9	-41.8	174.7	-66.4	-177.2	-177.7	-179.5	0	112	L37 S38 I39 C40 Y45 A46 E176 S179 Y183	L37-K42 HydrophobicContact CB-CD 4.48Å; L37-K42 HydrophobicContact CB-CG 4.02Å; S38-K42 PolarHBondContact O-N 2.91Å; S38-K42 VanDerWaalsContact O-N 3.09Å; I39-K42 PolarHBondContact O-N 3.17Å; C40-K42 VanDerWaalsContact C-N 3.31Å; C40-K42 PolarHBondContact O-N 3.42Å; K42-Y45 PolarHBondContact O-N 3.45Å; K42-A46 WeakPolarHBondContact O-CB 3.29Å; K42-A46 PolarHBondContact O-N 3.47Å; K42-E176 WeakPolarHBondContact CE-OE2 3.34Å; K42-E176 IonicContact NZ-OE1 3.05Å; K42-E176 IonicContact NZ-OE2 2.87Å; K42-E176 PolarHBondContact NZ-OE2 3.28Å; K42-S179 PolarHBondContact NZ-OG 2.67Å; K42-Y183 HydrophobicContact CB-CD2 4.13Å; K42-Y183 HydrophobicContact CB-CG 4.47Å; K42-Y183 HydrophobicContact CD-CD2 4.12Å; K42-Y183 HydrophobicContact CD-CE2 4.04Å
43	I	88.5	Confident	78.8	Confident	75 Å²	75	58.7 Å²	58.7	39%	0.385	29%	0.287	S	S	.	.	H	α-helix	trans	-68.5	-45.5	177.4	-68	169.8	0	0	0	110.6	I39 C40 Y45 A46 I47 Y183	I39-I43 HydrophobicContact CG2-CD1 3.85Å; I39-I43 HydrophobicContact CG2-CG1 4.4Å; I39-I43 WeakPolarHBondContact O-CG1 3.5Å; I39-I43 PolarHBondContact O-N 3.36Å; C40-I43 PolarHBondContact O-N 2.99Å; I43-Y45 VanDerWaalsContact C-N 3.28Å; I43-Y45 PolarHBondContact O-N 2.8Å; I43-A46 PolarHBondContact O-N 3.19Å; I43-A46 VanDerWaalsContact O-N 3.08Å; I43-I47 HydrophobicContact CG2-CD1 3.86Å; I43-I47 HydrophobicContact CG2-CG1 4.42Å; I43-I47 VanDerWaalsContact O-CG1 3.32Å; I43-I47 WeakPolarHBondContact O-CG1 3.49Å; I43-I47 PolarHBondContact O-N 2.98Å; I43-Y183 HydrophobicContact CG1-CD1 4.37Å; I43-Y183 HydrophobicContact CG1-CE1 4.43Å
44	C	87.2	Confident	81.7	Confident	17 Å²	17	51.3 Å²	51.3	12%	0.115	25%	0.252	C	S	.	.	H	α-helix	trans	-59.4	-40.1	175.6	-67.2	0	0	0	0	111.9	C40 V258 V263	C40-C44 WeakPolarHBondContact O-CB 3.43Å; C40-C44 PolarHBondContact O-N 3.1Å; C40-C44 PolarHBondContact O-SG 3.36Å; C44-V258 HydrophobicContact CB-CG1 4.13Å; C44-V263 HydrophobicContact CB-CG2 4.26Å
45	Y	87.5	Confident	84.2	Confident	2 Å²	2	41.2 Å²	41.2	1%	0.008	22%	0.215	C	C	.	.	H	α-helix	trans	-61.8	-48.6	171	175	-106	0	0	0	111.6	N41 K42 I43 I47 G48 Y163 L166 T167 I170 A180 R184 L259	N41-Y45 VanDerWaalsContact O-CB 3.31Å; N41-Y45 WeakPolarHBondContact O-CB 3.44Å; N41-Y45 PolarHBondContact O-N 3.29Å; K42-Y45 PolarHBondContact O-N 3.45Å; I43-Y45 VanDerWaalsContact C-N 3.28Å; I43-Y45 PolarHBondContact O-N 2.8Å; Y45-I47 VanDerWaalsContact C-N 3.31Å; Y45-I47 PolarHBondContact O-N 3.28Å; Y45-G48 PolarHBondContact O-N 3.49Å; Y45-G48 VanDerWaalsContact O-N 3.1Å; Y45-Y163 HydrophobicContact CD2-CD2 4.5Å; Y45-Y163 AromaticContact CD2-CE2 3.79Å; Y45-Y163 HydrophobicContact CD2-CE2 3.79Å; Y45-Y163 AromaticContact CE2-CD2 3.93Å; Y45-Y163 HydrophobicContact CE2-CD2 3.93Å; Y45-Y163 AromaticContact CE2-CE2 3.39Å; Y45-Y163 HydrophobicContact CE2-CE2 3.39Å; Y45-Y163 AromaticContact CE2-CZ 3.91Å; Y45-Y163 AromaticContact CZ-CE2 3.85Å; Y45-Y163 AromaticContact CZ-CZ 3.86Å; Y45-Y163 WeakPolarHBondContact O-CE2 3.46Å; Y45-Y163 PolarHBondContact O-OH 3.29Å; Y45-Y163 PolarHBondContact OH-O 2.87Å; Y45-Y163 VanDerWaalsContact OH-O 3.08Å; Y45-L166 HydrophobicContact CD2-CD2 4.14Å; Y45-L166 HydrophobicContact CE2-CB 4.1Å; Y45-L166 HydrophobicContact CE2-CD2 4.15Å; Y45-L166 HydrophobicContact CE2-CG 4.4Å; Y45-T167 HydrophobicContact CE1-CG2 3.49Å; Y45-T167 VanDerWaalsContact CE1-CG2 3.49Å; Y45-T167 HydrophobicContact CE2-CG2 4.39Å; Y45-T167 WeakPolarHBondContact OH-CG2 3.09Å; Y45-I170 HydrophobicContact CD2-CD1 3.28Å; Y45-I170 HydrophobicContact CE2-CD1 3.76Å; Y45-I170 HydrophobicContact CG-CD1 3.76Å; Y45-A180 HydrophobicContact CD1-CB 4.23Å; Y45-R184 HydrophobicContact CE1-CB 4.05Å; Y45-L259 HydrophobicContact CD2-CD1 4.32Å
46	A	89.1	Confident	85.9	Confident	0 Å²	0	39 Å²	39	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-61.3	-36.8	-178.3	0	0	0	0	0	113.5	K42 I43 G48 G49 Y163 Y183 V187	K42-A46 WeakPolarHBondContact O-CB 3.29Å; K42-A46 PolarHBondContact O-N 3.47Å; I43-A46 PolarHBondContact O-N 3.19Å; I43-A46 VanDerWaalsContact O-N 3.08Å; A46-G48 PolarHBondContact O-N 2.96Å; A46-G49 PolarHBondContact O-N 3.37Å; A46-Y163 PolarHBondContact O-OH 3.23Å; A46-Y183 VanDerWaalsContact CB-C 3.46Å; A46-Y183 WeakPolarHBondContact CB-O 3.23Å; A46-V187 HydrophobicContact CB-CB 4.12Å; A46-V187 HydrophobicContact CB-CG2 3.68Å; A46-V187 WeakPolarHBondContact O-CG1 3.46Å
47	I	90.4	Very high	87.4	Confident	46 Å²	46	30.9 Å²	30.9	24%	0.236	18%	0.178	C	C	.	.	H	α-helix	trans	-58.8	-30.3	176.2	-71.2	166.4	0	0	0	112.2	I43 Y45 G49 A50 C255 V258	I43-I47 HydrophobicContact CG2-CD1 3.86Å; I43-I47 HydrophobicContact CG2-CG1 4.42Å; I43-I47 VanDerWaalsContact O-CG1 3.32Å; I43-I47 WeakPolarHBondContact O-CG1 3.49Å; I43-I47 PolarHBondContact O-N 2.98Å; Y45-I47 VanDerWaalsContact C-N 3.31Å; Y45-I47 PolarHBondContact O-N 3.28Å; I47-G49 PolarHBondContact O-N 3.19Å; I47-A50 PolarHBondContact O-N 2.88Å; I47-C255 HydrophobicContact CG2-CB 3.82Å; I47-V258 HydrophobicContact CB-CG1 4.21Å; I47-V258 HydrophobicContact CD1-CG1 3.83Å; I47-V258 HydrophobicContact CG2-CB 4.11Å; I47-V258 HydrophobicContact CG2-CG1 4.02Å
48	G	86.5	Confident	88.6	Confident	1 Å²	1	29.5 Å²	29.5	1%	0.01	17%	0.17	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.4	-19.5	175.6	0	0	0	0	0	114.8	Y45 A46 P51 F159	Y45-G48 PolarHBondContact O-N 3.49Å; Y45-G48 VanDerWaalsContact O-N 3.1Å; A46-G48 PolarHBondContact O-N 2.96Å; G48-P51 WeakPolarHBondContact O-CD 3.47Å; G48-F159 VanDerWaalsContact O-CE1 3.31Å; G48-F159 WeakPolarHBondContact O-CE1 3.37Å
49	G	86.4	Confident	89.1	Confident	0 Å²	0	26.7 Å²	26.7	0%	0	15%	0.15	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.5	-23.1	-179.4	0	0	0	0	0	113.9	A46 I47 P51 Y52 Y163	A46-G49 PolarHBondContact O-N 3.37Å; I47-G49 PolarHBondContact O-N 3.19Å; G49-P51 VanDerWaalsContact C-CD 3.47Å; G49-Y52 PolarHBondContact O-N 3.43Å; G49-Y163 WeakPolarHBondContact CA-OH 3.41Å; G49-Y163 PolarHBondContact N-OH 2.81Å
50	A	91.5	Very high	89.4	Confident	8 Å²	8	21.5 Å²	21.5	7%	0.066	12%	0.124	C	C	.	.	H	α-helix	trans	-56.3	-44.3	-177.8	0	0	0	0	0	114	I47 Y52 Q53 I54 V187	I47-A50 PolarHBondContact O-N 2.88Å; A50-Y52 VanDerWaalsContact C-N 3.3Å; A50-Y52 PolarHBondContact O-N 3.41Å; A50-Q53 PolarHBondContact O-N 3.04Å; A50-I54 HydrophobicContact CB-CD1 3.96Å; A50-I54 WeakPolarHBondContact O-CB 3.44Å; A50-I54 WeakPolarHBondContact O-CG1 3.37Å; A50-I54 PolarHBondContact O-N 3.19Å; A50-V187 HydrophobicContact CB-CG1 3.91Å
51	P	91.6	Very high	89.5	Confident	1 Å²	1	18.6 Å²	18.6	1%	0.006	10%	0.103	C	C	.	.	H	α-helix	trans	-59.1	-37	-174.9	-26.6	36.3	0	0	0	114.7	G48 G49 T55 F159 Y252 C255	G48-P51 WeakPolarHBondContact O-CD 3.47Å; G49-P51 VanDerWaalsContact C-CD 3.47Å; P51-T55 WeakPolarHBondContact O-CB 3.47Å; P51-T55 WeakPolarHBondContact O-CG2 3.4Å; P51-T55 PolarHBondContact O-N 3.4Å; P51-T55 PolarHBondContact O-OG1 3.35Å; P51-F159 HydrophobicContact CG-CE1 4.4Å; P51-Y252 HydrophobicContact CB-CD1 4.21Å; P51-Y252 HydrophobicContact CB-CD2 3.5Å; P51-Y252 HydrophobicContact CB-CE1 4.22Å; P51-Y252 HydrophobicContact CB-CE2 3.51Å; P51-Y252 HydrophobicContact CB-CG 3.83Å; P51-Y252 HydrophobicContact CG-CG 4.42Å; P51-C255 HydrophobicContact CG-CB 3.49Å; P51-C255 VanDerWaalsContact CG-CB 3.49Å
52	Y	89.9	Confident	89.8	Confident	45 Å²	45	15.4 Å²	15.4	18%	0.176	9%	0.085	C	C	.	.	H	α-helix	trans	-64	-47	178.3	175.3	-105.6	0	0	0	111.5	G49 A50 T55 G56 Q156 H160 K433	G49-Y52 PolarHBondContact O-N 3.43Å; A50-Y52 VanDerWaalsContact C-N 3.3Å; A50-Y52 PolarHBondContact O-N 3.41Å; Y52-T55 PolarHBondContact O-OG1 3.04Å; Y52-G56 PolarHBondContact O-N 3.38Å; Y52-Q156 HydrophobicContact CD2-CG 3.95Å; Y52-H160 AromaticContact CD1-CD2 3.68Å; Y52-H160 AromaticContact CD1-NE2 3.67Å; Y52-H160 HydrophobicContact CD2-CB 3.98Å; Y52-H160 AromaticContact CD2-CD2 3.92Å; Y52-H160 AromaticContact CD2-CG 3.78Å; Y52-H160 AromaticContact CE1-NE2 3.93Å; Y52-H160 HydrophobicContact CG-CB 4.32Å; Y52-H160 AromaticContact CG-CD2 3.48Å; Y52-H160 VanDerWaalsContact CG-CD2 3.48Å; Y52-H160 AromaticContact CG-CG 3.85Å; Y52-H160 AromaticContact CG-NE2 3.98Å; Y52-K433 WeakPolarHBondContact OH-CE 3.5Å; Y52-K433 PolarHBondContact OH-NZ 3.25Å
53	Q	91	Very high	90	Very high	47 Å²	47	14.8 Å²	14.8	22%	0.22	8%	0.083	C	C	.	.	H	α-helix	trans	-72.8	-35.7	179.1	-62.5	-61.9	-6.6	0	0	112.6	A50 C57 E188 T192	A50-Q53 PolarHBondContact O-N 3.04Å; Q53-C57 WeakPolarHBondContact O-CB 3.29Å; Q53-C57 PolarHBondContact O-N 2.92Å; Q53-E188 WeakPolarHBondContact CB-O 3.36Å; Q53-E188 HydrophobicContact CG-CB 3.63Å; Q53-E188 HydrophobicContact CG-CG 3.61Å; Q53-E188 PolarHBondContact NE2-OE2 2.74Å; Q53-E188 VanDerWaalsContact NE2-OE2 3.09Å; Q53-T192 HydrophobicContact CB-CG2 3.82Å; Q53-T192 HydrophobicContact CG-CG2 4.49Å
54	I	93.7	Very high	90.1	Very high	3 Å²	3	11.2 Å²	11.2	2%	0.015	7%	0.065	C	C	.	.	H	α-helix	trans	-61.9	-53	178.4	-69.9	164.4	0	0	0	109.9	A50 A58 G191 S195 I248 M251	A50-I54 HydrophobicContact CB-CD1 3.96Å; A50-I54 WeakPolarHBondContact O-CB 3.44Å; A50-I54 WeakPolarHBondContact O-CG1 3.37Å; A50-I54 PolarHBondContact O-N 3.19Å; I54-A58 WeakPolarHBondContact O-CB 3.49Å; I54-A58 PolarHBondContact O-N 3.02Å; I54-A58 VanDerWaalsContact O-N 3.15Å; I54-G191 VanDerWaalsContact CG1-O 3.27Å; I54-G191 WeakPolarHBondContact CG1-O 3.46Å; I54-S195 VanDerWaalsContact O-CB 3.23Å; I54-S195 WeakPolarHBondContact O-CB 3.44Å; I54-S195 PolarHBondContact O-OG 3.38Å; I54-I248 HydrophobicContact CG2-CB 4.39Å; I54-I248 HydrophobicContact CG2-CD1 4.45Å; I54-I248 HydrophobicContact CG2-CG1 4.06Å; I54-I248 HydrophobicContact CG2-CG2 3.65Å; I54-M251 HydrophobicContact CD1-CE 4.36Å
55	T	93.5	Very high	90.1	Very high	2 Å²	2	10.5 Å²	10.5	1%	0.012	6%	0.06	C	C	.	.	H	α-helix	trans	-70.1	-38.3	-178.8	54.7	0	0	0	0	112.1	P51 Y52 A58 L59 Y128 F152 I248 Y252	P51-T55 WeakPolarHBondContact O-CB 3.47Å; P51-T55 WeakPolarHBondContact O-CG2 3.4Å; P51-T55 PolarHBondContact O-N 3.4Å; P51-T55 PolarHBondContact O-OG1 3.35Å; Y52-T55 PolarHBondContact O-OG1 3.04Å; T55-A58 PolarHBondContact O-N 3.03Å; T55-L59 VanDerWaalsContact O-CG 3.28Å; T55-L59 WeakPolarHBondContact O-CG 2.91Å; T55-L59 PolarHBondContact O-N 3.3Å; T55-Y128 HydrophobicContact CG2-CD2 4.04Å; T55-Y128 HydrophobicContact CG2-CE2 3.86Å; T55-Y128 HydrophobicContact CG2-CG 4.49Å; T55-F152 HydrophobicContact CG2-CE2 4.43Å; T55-F152 HydrophobicContact CG2-CZ 3.96Å; T55-I248 HydrophobicContact CG2-CG2 3.94Å; T55-Y252 HydrophobicContact CG2-CD2 4.2Å
56	G	90.8	Very high	90.3	Very high	29 Å²	29	10.4 Å²	10.4	30%	0.299	6%	0.059	S	C	.	.	H	α-helix	trans	-61.2	-47	176.3	0	0	0	0	0	113	Y52 L59 G60	Y52-G56 PolarHBondContact O-N 3.38Å; G56-L59 PolarHBondContact O-N 2.96Å; G56-G60 PolarHBondContact O-N 3.34Å
57	C	90.1	Very high	90.3	Very high	10 Å²	10	10.4 Å²	10.4	7%	0.068	6%	0.059	C	C	.	.	H	α-helix	trans	-65.2	-40.3	178.2	-172	0	0	0	0	112	Q53 G60 F61 T192 T196	Q53-C57 WeakPolarHBondContact O-CB 3.29Å; Q53-C57 PolarHBondContact O-N 2.92Å; C57-G60 PolarHBondContact O-N 2.92Å; C57-F61 WeakPolarHBondContact O-CD2 3.13Å; C57-F61 PolarHBondContact O-N 3.33Å; C57-T192 HydrophobicContact CB-CG2 4.32Å; C57-T196 PolarHBondContact SG-OG1 3.43Å; C57-T196 VanDerWaalsContact SG-OG1 3.35Å
58	A	91.9	Very high	90.2	Very high	0 Å²	0	8.2 Å²	8.2	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-59.2	-50.1	175.2	0	0	0	0	0	111.6	I54 T55 G60 F62 Y128 S195 I248	I54-A58 WeakPolarHBondContact O-CB 3.49Å; I54-A58 PolarHBondContact O-N 3.02Å; I54-A58 VanDerWaalsContact O-N 3.15Å; T55-A58 PolarHBondContact O-N 3.03Å; A58-G60 VanDerWaalsContact C-N 3.35Å; A58-F62 WeakPolarHBondContact O-CB 3.45Å; A58-F62 PolarHBondContact O-N 2.96Å; A58-F62 VanDerWaalsContact O-N 3.08Å; A58-Y128 VanDerWaalsContact CB-OH 3.23Å; A58-Y128 WeakPolarHBondContact CB-OH 3.36Å; A58-S195 WeakPolarHBondContact CB-OG 3.49Å; A58-S195 PolarHBondContact N-OG 2.92Å; A58-I248 HydrophobicContact CB-CD1 4.25Å
59	L	92.1	Very high	90	Very high	6 Å²	6	8.6 Å²	8.6	3%	0.031	5%	0.05	C	C	.	.	H	α-helix	trans	-69.3	-33.3	179	-63.8	169	0	0	0	112.1	T55 G56 L63 Y128 I131 W132 Y149 F152	T55-L59 VanDerWaalsContact O-CG 3.28Å; T55-L59 WeakPolarHBondContact O-CG 2.91Å; T55-L59 PolarHBondContact O-N 3.3Å; G56-L59 PolarHBondContact O-N 2.96Å; L59-L63 HydrophobicContact CB-CB 4.45Å; L59-L63 HydrophobicContact CB-CD2 4.44Å; L59-L63 HydrophobicContact CD2-CB 4.33Å; L59-L63 HydrophobicContact CD2-CD1 4.17Å; L59-L63 HydrophobicContact CD2-CD2 4Å; L59-L63 HydrophobicContact CD2-CG 4.4Å; L59-L63 WeakPolarHBondContact O-CB 3.21Å; L59-L63 PolarHBondContact O-N 3.14Å; L59-Y128 HydrophobicContact CD1-CE2 4.34Å; L59-Y128 HydrophobicContact CD2-CE2 4.2Å; L59-Y128 HydrophobicContact CG-CE2 4.16Å; L59-I131 HydrophobicContact CD2-CG2 4.25Å; L59-W132 HydrophobicContact CD2-CZ2 3.89Å; L59-Y149 HydrophobicContact CD1-CE2 3.99Å; L59-F152 HydrophobicContact CD1-CD1 3.95Å; L59-F152 HydrophobicContact CD1-CE1 3.49Å; L59-F152 VanDerWaalsContact CD1-CE1 3.49Å; L59-F152 HydrophobicContact CD1-CZ 4.43Å
60	G	89.1	Confident	89.9	Confident	1 Å²	1	8.6 Å²	8.6	1%	0.01	5%	0.05	C	C	.	.	H	α-helix	trans	-61	-52.6	178.2	0	0	0	0	0	113.3	G56 C57 A58	G56-G60 PolarHBondContact O-N 3.34Å; C57-G60 PolarHBondContact O-N 2.92Å; A58-G60 VanDerWaalsContact C-N 3.35Å
61	F	88.8	Confident	89.6	Confident	14 Å²	14	8.2 Å²	8.2	6%	0.061	5%	0.046	C	C	.	.	H	α-helix	trans	-86.9	-34.1	-175.5	-72.6	-68.4	0	0	0	114.6	C57 E309 A313 L330 M334	C57-F61 WeakPolarHBondContact O-CD2 3.13Å; C57-F61 PolarHBondContact O-N 3.33Å; F61-E309 HydrophobicContact CD1-CG 3.93Å; F61-E309 WeakPolarHBondContact CD1-O 3.23Å; F61-E309 HydrophobicContact CD2-CG 4.4Å; F61-E309 HydrophobicContact CE1-CB 4.22Å; F61-E309 HydrophobicContact CE1-CG 3.51Å; F61-E309 HydrophobicContact CE2-CG 4.01Å; F61-E309 HydrophobicContact CG-CG 4.37Å; F61-E309 HydrophobicContact CZ-CB 4.49Å; F61-E309 HydrophobicContact CZ-CG 3.54Å; F61-A313 WeakPolarHBondContact O-CB 3.44Å; F61-L330 HydrophobicContact CB-CD1 4.31Å; F61-L330 HydrophobicContact CD1-CD1 4.29Å; F61-L330 HydrophobicContact CD1-CD2 3.45Å; F61-L330 VanDerWaalsContact CD1-CD2 3.45Å; F61-L330 HydrophobicContact CE1-CD2 3.42Å; F61-L330 VanDerWaalsContact CE1-CD2 3.42Å; F61-L330 HydrophobicContact CG-CD1 4.38Å; F61-L330 HydrophobicContact CG-CD2 4.13Å; F61-L330 HydrophobicContact CZ-CD2 4.1Å; F61-M334 HydrophobicContact CE2-CE 3.79Å; F61-M334 HydrophobicContact CE2-SD 4.09Å; F61-M334 HydrophobicContact CZ-CE 3.47Å; F61-M334 VanDerWaalsContact CZ-CE 3.47Å; F61-M334 HydrophobicContact CZ-SD 4.38Å
62	F	89.8	Confident	89.3	Confident	0 Å²	0	12.4 Å²	12.4	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-108.7	-23.2	-165.8	-62.8	-78.2	0	0	0	114.6	A58 Q64 L65 Y66 W132 Q199 Y241 F326 H327 L330	A58-F62 WeakPolarHBondContact O-CB 3.45Å; A58-F62 PolarHBondContact O-N 2.96Å; A58-F62 VanDerWaalsContact O-N 3.08Å; F62-Q64 PolarHBondContact O-N 2.94Å; F62-L65 PolarHBondContact O-N 3.02Å; F62-Y66 VanDerWaalsContact O-CB 3.31Å; F62-Y66 WeakPolarHBondContact O-CB 3.04Å; F62-Y66 PolarHBondContact O-N 3.28Å; F62-W132 HydrophobicContact CB-CH2 3.88Å; F62-W132 HydrophobicContact CB-CZ3 4.38Å; F62-Q199 HydrophobicContact CB-CG 4.32Å; F62-Q199 HydrophobicContact CD1-CG 4.14Å; F62-Q199 HydrophobicContact CD2-CB 3.98Å; F62-Q199 HydrophobicContact CD2-CG 3.56Å; F62-Q199 HydrophobicContact CE1-CG 4.38Å; F62-Q199 HydrophobicContact CE2-CB 3.79Å; F62-Q199 HydrophobicContact CE2-CG 3.82Å; F62-Q199 HydrophobicContact CG-CG 3.73Å; F62-Q199 HydrophobicContact CZ-CB 4.27Å; F62-Q199 HydrophobicContact CZ-CG 4.22Å; F62-Y241 HydrophobicContact CB-CE1 4.32Å; F62-F326 AromaticContact CE1-CE2 3.92Å; F62-F326 HydrophobicContact CE1-CE2 3.92Å; F62-H327 AromaticContact CE1-CD2 3.54Å; F62-L330 HydrophobicContact CE1-CD1 4.33Å; F62-L330 HydrophobicContact CZ-CD1 4.02Å
63	L	91.4	Very high	89.1	Confident	3 Å²	3	10.9 Å²	10.9	2%	0.016	6%	0.061	C	C	.	.	H	α-helix	trans	-63.5	-44.4	-174.1	-175.9	62.2	0	0	0	112	L59 L65 Y66 L67 L82 I131 Y149	L59-L63 HydrophobicContact CB-CB 4.45Å; L59-L63 HydrophobicContact CB-CD2 4.44Å; L59-L63 HydrophobicContact CD2-CB 4.33Å; L59-L63 HydrophobicContact CD2-CD1 4.17Å; L59-L63 HydrophobicContact CD2-CD2 4Å; L59-L63 HydrophobicContact CD2-CG 4.4Å; L59-L63 WeakPolarHBondContact O-CB 3.21Å; L59-L63 PolarHBondContact O-N 3.14Å; L63-L65 PolarHBondContact O-N 2.94Å; L63-Y66 PolarHBondContact O-N 2.95Å; L63-L67 HydrophobicContact CD1-CD1 4.36Å; L63-L67 HydrophobicContact CD1-CG 4.2Å; L63-L67 HydrophobicContact CG-CD1 4.08Å; L63-L67 HydrophobicContact CG-CG 4.33Å; L63-L67 VanDerWaalsContact O-CG 3.32Å; L63-L67 WeakPolarHBondContact O-CG 3.17Å; L63-L67 PolarHBondContact O-N 2.72Å; L63-L82 HydrophobicContact CB-CD2 4.33Å; L63-L82 HydrophobicContact CD2-CD2 3.51Å; L63-L82 HydrophobicContact CG-CD2 3.83Å; L63-I131 HydrophobicContact CD1-CG2 3.78Å; L63-Y149 HydrophobicContact CD2-CD1 4.37Å; L63-Y149 HydrophobicContact CD2-CE1 3.96Å; L63-Y149 HydrophobicContact CD2-CE2 4.5Å
64	Q	90.2	Very high	88.9	Confident	1 Å²	1	13 Å²	13	1%	0.005	7%	0.074	C	C	.	.	H	α-helix	trans	-61.4	-45.4	179.2	-172.9	176.9	-23	0	0	111.3	F62 Y66 L67 L68 L82 G310 N311 L314 T444	F62-Q64 PolarHBondContact O-N 2.94Å; Q64-Y66 VanDerWaalsContact C-N 3.34Å; Q64-Y66 PolarHBondContact O-N 3Å; Q64-L67 PolarHBondContact O-N 3.23Å; Q64-L68 HydrophobicContact CG-CD1 4.25Å; Q64-L68 WeakPolarHBondContact O-CG 3.18Å; Q64-L68 PolarHBondContact O-N 3.17Å; Q64-L82 HydrophobicContact CB-CD1 3.82Å; Q64-L82 HydrophobicContact CG-CD1 3.78Å; Q64-G310 PolarHBondContact OE1-O 3.32Å; Q64-G310 VanDerWaalsContact OE1-O 3.09Å; Q64-N311 PolarHBondContact NE2-OD1 3.38Å; Q64-L314 HydrophobicContact CG-CD1 3.89Å; Q64-T444 PolarHBondContact NE2-OG1 3.05Å
65	L	87.9	Confident	88.6	Confident	2 Å²	2	13.1 Å²	13.1	1%	0.01	8%	0.075	C	C	.	.	H	α-helix	trans	-63.9	-39	176.3	-174.4	145.3	0	0	0	111.7	F62 L63 D69 Y241 A313 L314 F326	F62-L65 PolarHBondContact O-N 3.02Å; L63-L65 PolarHBondContact O-N 2.94Å; L65-D69 WeakPolarHBondContact O-CB 3.23Å; L65-D69 PolarHBondContact O-N 3.42Å; L65-Y241 WeakPolarHBondContact CD2-OH 3.24Å; L65-A313 HydrophobicContact CD1-CB 4.17Å; L65-L314 HydrophobicContact CB-CD2 4.37Å; L65-L314 HydrophobicContact CD1-CD2 4.42Å; L65-L314 HydrophobicContact CG-CD2 4.4Å; L65-F326 HydrophobicContact CD1-CE2 4.37Å; L65-F326 HydrophobicContact CD1-CZ 4.01Å
66	Y	89.8	Confident	88.4	Confident	0 Å²	0	17.4 Å²	17.4	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-65.7	-45.5	177.1	173.5	-89.4	0	0	0	112.5	F62 L63 Q64 L68 V70 A71 W132 V134 Y145 Y241	F62-Y66 VanDerWaalsContact O-CB 3.31Å; F62-Y66 WeakPolarHBondContact O-CB 3.04Å; F62-Y66 PolarHBondContact O-N 3.28Å; L63-Y66 PolarHBondContact O-N 2.95Å; Q64-Y66 VanDerWaalsContact C-N 3.34Å; Q64-Y66 PolarHBondContact O-N 3Å; Y66-L68 VanDerWaalsContact C-N 3.29Å; Y66-L68 PolarHBondContact O-N 3.16Å; Y66-V70 HydrophobicContact CD2-CB 3.66Å; Y66-V70 HydrophobicContact CD2-CG1 3.86Å; Y66-V70 HydrophobicContact CD2-CG2 3.95Å; Y66-V70 HydrophobicContact CE2-CB 3.88Å; Y66-V70 HydrophobicContact CE2-CG1 3.56Å; Y66-V70 HydrophobicContact CG-CB 4.24Å; Y66-V70 WeakPolarHBondContact O-CA 3.42Å; Y66-V70 WeakPolarHBondContact O-CB 3.13Å; Y66-V70 PolarHBondContact O-N 3.09Å; Y66-A71 HydrophobicContact CE1-CB 4.26Å; Y66-A71 PolarHBondContact O-N 3.11Å; Y66-W132 HydrophobicContact CD1-CE3 4.22Å; Y66-W132 HydrophobicContact CD1-CZ3 4.35Å; Y66-W132 AromaticContact CD2-CE3 3.71Å; Y66-W132 HydrophobicContact CD2-CE3 3.71Å; Y66-W132 AromaticContact CD2-CZ3 3.96Å; Y66-W132 HydrophobicContact CD2-CZ3 3.96Å; Y66-W132 HydrophobicContact CE2-CE3 4.03Å; Y66-W132 AromaticContact CG-CE3 3.81Å; Y66-W132 HydrophobicContact CG-CE3 3.81Å; Y66-W132 AromaticContact CG-CZ3 3.75Å; Y66-W132 HydrophobicContact CG-CZ3 3.75Å; Y66-W132 PolarHBondContact OH-O 2.83Å; Y66-V134 WeakPolarHBondContact OH-CG2 3.26Å; Y66-Y145 HydrophobicContact CE1-CE1 4Å; Y66-Y241 AromaticContact CD2-CD1 3.82Å; Y66-Y241 HydrophobicContact CD2-CD1 3.82Å; Y66-Y241 AromaticContact CD2-CD2 3.78Å; Y66-Y241 HydrophobicContact CD2-CD2 3.78Å; Y66-Y241 HydrophobicContact CD2-CE1 4.06Å; Y66-Y241 HydrophobicContact CD2-CE2 4.03Å; Y66-Y241 AromaticContact CD2-CG 3.67Å; Y66-Y241 HydrophobicContact CD2-CG 3.67Å; Y66-Y241 HydrophobicContact CE2-CD1 4.44Å; Y66-Y241 HydrophobicContact CE2-CD2 4.2Å; Y66-Y241 AromaticContact CE2-CG 3.98Å; Y66-Y241 HydrophobicContact CE2-CG 3.98Å
67	L	89.8	Confident	88.5	Confident	0 Å²	0	20.9 Å²	20.9	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-61.8	-40.1	179.5	-69.5	173.9	0	0	0	111.5	L63 Q64 Q72 L73 A78 I81 L82 Y145	L63-L67 HydrophobicContact CD1-CD1 4.36Å; L63-L67 HydrophobicContact CD1-CG 4.2Å; L63-L67 HydrophobicContact CG-CD1 4.08Å; L63-L67 HydrophobicContact CG-CG 4.33Å; L63-L67 VanDerWaalsContact O-CG 3.32Å; L63-L67 WeakPolarHBondContact O-CG 3.17Å; L63-L67 PolarHBondContact O-N 2.72Å; Q64-L67 PolarHBondContact O-N 3.23Å; L67-Q72 PolarHBondContact O-N 3.32Å; L67-L73 HydrophobicContact CD2-CD1 3.99Å; L67-L73 PolarHBondContact O-N 3.5Å; L67-A78 HydrophobicContact CB-CB 4.11Å; L67-A78 HydrophobicContact CD1-CB 4.35Å; L67-I81 HydrophobicContact CD1-CB 4.25Å; L67-I81 HydrophobicContact CD1-CD1 4.43Å; L67-I81 HydrophobicContact CD1-CG2 3.91Å; L67-I81 HydrophobicContact CD2-CD1 4.31Å; L67-L82 HydrophobicContact CD1-CD2 4.11Å; L67-L82 HydrophobicContact CD1-CG 4.16Å; L67-Y145 HydrophobicContact CD2-CD1 4Å; L67-Y145 HydrophobicContact CD2-CD2 4.07Å; L67-Y145 HydrophobicContact CD2-CE1 4.25Å; L67-Y145 HydrophobicContact CD2-CE2 4.3Å; L67-Y145 HydrophobicContact CD2-CG 3.92Å
68	L	87.8	Confident	88.5	Confident	0 Å²	0	20.4 Å²	20.4	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-75.1	-61.8	178	-63.5	173	0	0	0	111.2	Q64 Y66 Q72 P75 A78 L314 Y452 T454	Q64-L68 HydrophobicContact CG-CD1 4.25Å; Q64-L68 WeakPolarHBondContact O-CG 3.18Å; Q64-L68 PolarHBondContact O-N 3.17Å; Y66-L68 VanDerWaalsContact C-N 3.29Å; Y66-L68 PolarHBondContact O-N 3.16Å; L68-Q72 VanDerWaalsContact O-CA 3.27Å; L68-Q72 WeakPolarHBondContact O-CA 3.44Å; L68-Q72 PolarHBondContact O-N 3.05Å; L68-P75 HydrophobicContact CD2-CB 4.08Å; L68-P75 HydrophobicContact CD2-CG 3.95Å; L68-A78 HydrophobicContact CD2-CB 4.06Å; L68-L314 HydrophobicContact CD1-CD1 3.79Å; L68-L314 HydrophobicContact CD1-CD2 4.1Å; L68-Y452 HydrophobicContact CB-CE1 4.22Å; L68-Y452 HydrophobicContact CD1-CD1 4.44Å; L68-Y452 HydrophobicContact CD1-CE1 4.06Å; L68-T454 WeakPolarHBondContact O-CG2 3.4Å
69	D	82.8	Confident	88.5	Confident	8 Å²	8	20.8 Å²	20.8	4%	0.043	10%	0.098	C	C	.	.	H	α-helix	trans	-84.2	-27	-168.1	-76.5	-15.7	0	0	0	114.5	L65 R455	L65-D69 WeakPolarHBondContact O-CB 3.23Å; L65-D69 PolarHBondContact O-N 3.42Å; D69-R455 HydrophobicContact CB-CG 4.15Å; D69-R455 VanDerWaalsContact O-CD 3.22Å; D69-R455 WeakPolarHBondContact O-CD 3.49Å; D69-R455 WeakPolarHBondContact O-CG 3.33Å; D69-R455 PolarHBondContact OD1-N 2.84Å
70	V	84.8	Confident	88.6	Confident	0 Å²	0	23 Å²	23	0%	0	11%	0.109	C	C	.	.	T	Hydrogen-bonded Turn	trans	-106	-48.5	-173	-176.3	0	0	0	0	112.4	Y66 Q72 V134 Q237 R238 Y241	Y66-V70 HydrophobicContact CD2-CB 3.66Å; Y66-V70 HydrophobicContact CD2-CG1 3.86Å; Y66-V70 HydrophobicContact CD2-CG2 3.95Å; Y66-V70 HydrophobicContact CE2-CB 3.88Å; Y66-V70 HydrophobicContact CE2-CG1 3.56Å; Y66-V70 HydrophobicContact CG-CB 4.24Å; Y66-V70 WeakPolarHBondContact O-CA 3.42Å; Y66-V70 WeakPolarHBondContact O-CB 3.13Å; Y66-V70 PolarHBondContact O-N 3.09Å; V70-Q72 VanDerWaalsContact C-N 3.26Å; V70-V134 HydrophobicContact CG1-CG2 4.3Å; V70-Q237 HydrophobicContact CG2-CG 4.18Å; V70-R238 HydrophobicContact CG1-CB 4.49Å; V70-R238 HydrophobicContact CG1-CG 3.47Å; V70-R238 VanDerWaalsContact CG1-CG 3.47Å; V70-R238 PolarHBondContact O-NH2 2.87Å; V70-Y241 HydrophobicContact CG2-CD2 4.1Å; V70-Y241 HydrophobicContact CG2-CE2 3.72Å
71	A	84.8	Confident	88.8	Confident	0 Å²	0	23.1 Å²	23.1	0%	0	11%	0.109	C	C	.	.	S	Bend	trans	-76.6	-17.6	174.6	0	0	0	0	0	112.1	Y66 L73 Y145	Y66-A71 HydrophobicContact CE1-CB 4.26Å; Y66-A71 PolarHBondContact O-N 3.11Å; A71-L73 VanDerWaalsContact C-N 3.3Å; A71-L73 HydrophobicContact CB-CD1 4.43Å; A71-L73 HydrophobicContact CB-CG 4.24Å; A71-L73 PolarHBondContact O-N 2.62Å; A71-Y145 HydrophobicContact CB-CE2 3.88Å; A71-Y145 WeakPolarHBondContact CB-OH 3.33Å
72	Q	85.4	Confident	88.9	Confident	89 Å²	89	22.6 Å²	22.6	42%	0.416	11%	0.107	S	C	.	.			trans	58.8	40.3	176.1	-55.5	179.7	-60.4	0	0	112.5	L67 L68 V70 T454	L67-Q72 PolarHBondContact O-N 3.32Å; L68-Q72 VanDerWaalsContact O-CA 3.27Å; L68-Q72 WeakPolarHBondContact O-CA 3.44Å; L68-Q72 PolarHBondContact O-N 3.05Å; V70-Q72 VanDerWaalsContact C-N 3.26Å; Q72-T454 HydrophobicContact CB-CG2 4.5Å
73	L	86.6	Confident	89.1	Confident	13 Å²	13	26.4 Å²	26.4	7%	0.068	12%	0.124	C	C	.	.			trans	-87.2	148.4	174.2	-65.2	174.9	0	0	0	110.7	L67 A71 I81 K141 V142 Y145	L67-L73 HydrophobicContact CD2-CD1 3.99Å; L67-L73 PolarHBondContact O-N 3.5Å; A71-L73 VanDerWaalsContact C-N 3.3Å; A71-L73 HydrophobicContact CB-CD1 4.43Å; A71-L73 HydrophobicContact CB-CG 4.24Å; A71-L73 PolarHBondContact O-N 2.62Å; L73-I81 HydrophobicContact CD1-CD1 3.62Å; L73-K141 HydrophobicContact CD2-CB 4.06Å; L73-V142 HydrophobicContact CD2-CG2 4.14Å; L73-Y145 HydrophobicContact CD1-CD2 3.73Å; L73-Y145 HydrophobicContact CD1-CE2 3.94Å
74	D	86.4	Confident	89.2	Confident	93 Å²	93	29.3 Å²	29.3	50%	0.497	14%	0.138	S	C	.	.			trans	-64	147.1	171.6	-59.4	-42.1	0	0	0	110.6	F76 Y77 A78	D74-F76 PolarHBondContact O-N 2.65Å; D74-Y77 HydrophobicContact CB-CD2 4Å; D74-Y77 HydrophobicContact CB-CE2 4.49Å; D74-Y77 PolarHBondContact O-N 3.45Å; D74-A78 PolarHBondContact O-N 3.42Å
75	P	86.9	Confident	89.2	Confident	5 Å²	5	29.3 Å²	29.3	3%	0.032	14%	0.139	C	C	.	.	H	α-helix	trans	-55.6	-36.1	179.5	-21.6	30.7	0	0	0	112.9	L68 Y77 A78 S79 T444 D448 Y452	L68-P75 HydrophobicContact CD2-CB 4.08Å; L68-P75 HydrophobicContact CD2-CG 3.95Å; P75-Y77 PolarHBondContact O-N 2.79Å; P75-A78 PolarHBondContact O-N 3.3Å; P75-S79 WeakPolarHBondContact O-CB 3.32Å; P75-S79 PolarHBondContact O-N 3.45Å; P75-T444 HydrophobicContact CB-CG2 4.25Å; P75-T444 VanDerWaalsContact O-CG2 3.29Å; P75-T444 WeakPolarHBondContact O-CG2 3.46Å; P75-D448 HydrophobicContact CB-CB 3.82Å; P75-Y452 HydrophobicContact CG-CD1 4.22Å
76	F	90.2	Very high	89.3	Confident	92 Å²	92	30.6 Å²	30.6	40%	0.404	14%	0.144	S	C	.	.	H	α-helix	trans	-52.1	-52.3	172.3	-176.7	-102.7	0	0	0	113	D74 S79 I80 L445 D448	D74-F76 PolarHBondContact O-N 2.65Å; F76-S79 WeakPolarHBondContact O-CB 3.36Å; F76-S79 PolarHBondContact O-N 2.99Å; F76-S79 PolarHBondContact O-OG 3.37Å; F76-I80 HydrophobicContact CD1-CD1 4.06Å; F76-I80 HydrophobicContact CE1-CD1 3.51Å; F76-I80 HydrophobicContact CZ-CD1 3.78Å; F76-I80 PolarHBondContact O-N 3.23Å; F76-L445 HydrophobicContact CD2-CD1 3.81Å; F76-L445 HydrophobicContact CE2-CD1 4.25Å; F76-D448 PolarHBondContact N-OD1 3.18Å
77	Y	91.5	Very high	89.3	Confident	102 Å²	102	31.5 Å²	31.5	40%	0.4	15%	0.151	S	C	.	.	H	α-helix	trans	-70.4	-37	-179.7	-63.8	-65.2	0	0	0	112.6	D74 P75 S79 I80 I81 V142	D74-Y77 HydrophobicContact CB-CD2 4Å; D74-Y77 HydrophobicContact CB-CE2 4.49Å; D74-Y77 PolarHBondContact O-N 3.45Å; P75-Y77 PolarHBondContact O-N 2.79Å; Y77-S79 VanDerWaalsContact C-N 3.27Å; Y77-S79 PolarHBondContact O-N 3.46Å; Y77-I80 PolarHBondContact O-N 3.11Å; Y77-I81 WeakPolarHBondContact O-CD1 3.47Å; Y77-I81 WeakPolarHBondContact O-CG1 3.5Å; Y77-I81 PolarHBondContact O-N 3.16Å; Y77-V142 HydrophobicContact CD1-CG1 4.08Å; Y77-V142 HydrophobicContact CD1-CG2 3.8Å; Y77-V142 HydrophobicContact CD2-CG2 4.34Å; Y77-V142 HydrophobicContact CE1-CG2 4.48Å; Y77-V142 HydrophobicContact CG-CG2 3.71Å
78	A	91.3	Very high	89.5	Confident	0 Å²	0	37.1 Å²	37.1	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-60.2	-39	174.3	0	0	0	0	0	111.4	L67 L68 D74 P75 I80 I81 L82 T444	L67-A78 HydrophobicContact CB-CB 4.11Å; L67-A78 HydrophobicContact CD1-CB 4.35Å; L68-A78 HydrophobicContact CD2-CB 4.06Å; D74-A78 PolarHBondContact O-N 3.42Å; P75-A78 PolarHBondContact O-N 3.3Å; A78-I80 PolarHBondContact O-N 2.99Å; A78-I81 PolarHBondContact O-N 2.99Å; A78-L82 VanDerWaalsContact O-CG 3.28Å; A78-L82 WeakPolarHBondContact O-CG 3.32Å; A78-L82 PolarHBondContact O-N 3.25Å; A78-T444 HydrophobicContact CB-CG2 3.93Å
79	S	91.6	Very high	89.5	Confident	8 Å²	8	37.3 Å²	37.3	6%	0.056	17%	0.173	C	C	.	.	H	α-helix	trans	-61	-42.9	176.5	81.1	0	0	0	0	112.4	P75 F76 Y77 L82 F83 G441	P75-S79 WeakPolarHBondContact O-CB 3.32Å; P75-S79 PolarHBondContact O-N 3.45Å; F76-S79 WeakPolarHBondContact O-CB 3.36Å; F76-S79 PolarHBondContact O-N 2.99Å; F76-S79 PolarHBondContact O-OG 3.37Å; Y77-S79 VanDerWaalsContact C-N 3.27Å; Y77-S79 PolarHBondContact O-N 3.46Å; S79-L82 PolarHBondContact O-N 3.27Å; S79-F83 VanDerWaalsContact O-CB 3.23Å; S79-F83 WeakPolarHBondContact O-CB 3.45Å; S79-F83 PolarHBondContact O-N 2.73Å; S79-G441 WeakPolarHBondContact CB-O 3.47Å
80	I	93.2	Very high	89.8	Confident	53 Å²	53	37 Å²	37	27%	0.272	17%	0.171	S	C	.	.	H	α-helix	trans	-65	-45.3	178.3	-66.6	172.7	0	0	0	110.4	F76 Y77 A78 I84 I146	F76-I80 HydrophobicContact CD1-CD1 4.06Å; F76-I80 HydrophobicContact CE1-CD1 3.51Å; F76-I80 HydrophobicContact CZ-CD1 3.78Å; F76-I80 PolarHBondContact O-N 3.23Å; Y77-I80 PolarHBondContact O-N 3.11Å; A78-I80 PolarHBondContact O-N 2.99Å; I80-I84 HydrophobicContact CG2-CD1 3.47Å; I80-I84 VanDerWaalsContact CG2-CD1 3.47Å; I80-I84 HydrophobicContact CG2-CG1 4.19Å; I80-I84 VanDerWaalsContact O-CB 3.32Å; I80-I84 WeakPolarHBondContact O-CB 3.4Å; I80-I84 VanDerWaalsContact O-CG1 3.28Å; I80-I84 WeakPolarHBondContact O-CG1 3.33Å; I80-I84 PolarHBondContact O-N 3.08Å; I80-I146 HydrophobicContact CG2-CD1 4.15Å
81	I	93.4	Very high	89.9	Confident	2 Å²	2	40.4 Å²	40.4	1%	0.01	19%	0.192	C	C	.	.	H	α-helix	trans	-59.7	-49.3	179	-67.4	159.5	0	0	0	110.7	L67 L73 Y77 A78 G85 V142 Y145 I146 Y149	L67-I81 HydrophobicContact CD1-CB 4.25Å; L67-I81 HydrophobicContact CD1-CD1 4.43Å; L67-I81 HydrophobicContact CD1-CG2 3.91Å; L67-I81 HydrophobicContact CD2-CD1 4.31Å; L73-I81 HydrophobicContact CD1-CD1 3.62Å; Y77-I81 WeakPolarHBondContact O-CD1 3.47Å; Y77-I81 WeakPolarHBondContact O-CG1 3.5Å; Y77-I81 PolarHBondContact O-N 3.16Å; A78-I81 PolarHBondContact O-N 2.99Å; I81-G85 PolarHBondContact O-N 3.31Å; I81-V142 HydrophobicContact CD1-CG1 4.3Å; I81-V142 HydrophobicContact CG1-CG1 4.29Å; I81-Y145 HydrophobicContact CD1-CD2 4.39Å; I81-Y145 HydrophobicContact CD1-CG 4.43Å; I81-I146 HydrophobicContact CB-CG1 4.47Å; I81-I146 HydrophobicContact CG1-CD1 4.45Å; I81-I146 HydrophobicContact CG1-CG1 3.76Å; I81-Y149 HydrophobicContact CG2-CD1 4.17Å
82	L	91.9	Very high	90	Very high	3 Å²	3	40.7 Å²	40.7	2%	0.016	19%	0.194	C	C	.	.	H	α-helix	trans	-66.7	-43.2	-177.7	-66.8	172.8	0	0	0	111.9	L63 Q64 L67 A78 S79 R86 L440	L63-L82 HydrophobicContact CB-CD2 4.33Å; L63-L82 HydrophobicContact CD2-CD2 3.51Å; L63-L82 HydrophobicContact CG-CD2 3.83Å; Q64-L82 HydrophobicContact CB-CD1 3.82Å; Q64-L82 HydrophobicContact CG-CD1 3.78Å; L67-L82 HydrophobicContact CD1-CD2 4.11Å; L67-L82 HydrophobicContact CD1-CG 4.16Å; A78-L82 VanDerWaalsContact O-CG 3.28Å; A78-L82 WeakPolarHBondContact O-CG 3.32Å; A78-L82 PolarHBondContact O-N 3.25Å; S79-L82 PolarHBondContact O-N 3.27Å; L82-R86 WeakPolarHBondContact O-CB 3.42Å; L82-R86 WeakPolarHBondContact O-CG 3.42Å; L82-R86 PolarHBondContact O-N 3.01Å; L82-L440 HydrophobicContact CB-CB 4.25Å; L82-L440 HydrophobicContact CD1-CD2 4.24Å
83	F	93	Very high	90	Very high	81 Å²	81	37.3 Å²	37.3	36%	0.355	18%	0.179	S	C	.	.	H	α-helix	trans	-63.8	-53.8	177.8	177.5	-102.2	0	0	0	111.8	S79 G85 R86 A87 V438	S79-F83 VanDerWaalsContact O-CB 3.23Å; S79-F83 WeakPolarHBondContact O-CB 3.45Å; S79-F83 PolarHBondContact O-N 2.73Å; F83-G85 PolarHBondContact O-N 3.12Å; F83-R86 PolarHBondContact O-N 3.31Å; F83-A87 VanDerWaalsContact O-CB 3.23Å; F83-A87 WeakPolarHBondContact O-CB 2.95Å; F83-A87 PolarHBondContact O-N 3.36Å; F83-V438 HydrophobicContact CE2-CG2 3.88Å
84	I	93.7	Very high	89.7	Confident	63 Å²	63	38.1 Å²	38.1	32%	0.323	19%	0.185	S	C	.	.	H	α-helix	trans	-61.5	-44.9	-177.4	-68.7	177.2	0	0	0	110.4	I80 R86 A87 W88 I146	I80-I84 HydrophobicContact CG2-CD1 3.47Å; I80-I84 VanDerWaalsContact CG2-CD1 3.47Å; I80-I84 HydrophobicContact CG2-CG1 4.19Å; I80-I84 VanDerWaalsContact O-CB 3.32Å; I80-I84 WeakPolarHBondContact O-CB 3.4Å; I80-I84 VanDerWaalsContact O-CG1 3.28Å; I80-I84 WeakPolarHBondContact O-CG1 3.33Å; I80-I84 PolarHBondContact O-N 3.08Å; I84-R86 PolarHBondContact O-N 3.18Å; I84-A87 PolarHBondContact O-N 3.21Å; I84-W88 WeakPolarHBondContact O-CB 3.45Å; I84-W88 PolarHBondContact O-N 3.41Å; I84-I146 HydrophobicContact CD1-CD1 4.3Å; I84-I146 HydrophobicContact CG2-CG2 4.19Å
85	G	91.2	Very high	89.5	Confident	1 Å²	1	36.9 Å²	36.9	1%	0.01	18%	0.181	C	C	.	.	H	α-helix	trans	-64.9	-38.1	-178	0	0	0	0	0	113.8	I81 F83 D89	I81-G85 PolarHBondContact O-N 3.31Å; F83-G85 PolarHBondContact O-N 3.12Å; G85-D89 WeakPolarHBondContact O-CB 3.46Å; G85-D89 PolarHBondContact O-N 3.48Å; G85-D89 VanDerWaalsContact O-N 3.1Å
86	R	89.9	Confident	89.2	Confident	30 Å²	30	37.1 Å²	37.1	11%	0.113	18%	0.182	C	C	.	.	H	α-helix	trans	-75.9	-36.7	175.4	-71.2	-71.1	-175	139.6	0.9	112.8	L82 F83 I84 W88 D89 A90 Y149 S436 L440	L82-R86 WeakPolarHBondContact O-CB 3.42Å; L82-R86 WeakPolarHBondContact O-CG 3.42Å; L82-R86 PolarHBondContact O-N 3.01Å; F83-R86 PolarHBondContact O-N 3.31Å; I84-R86 PolarHBondContact O-N 3.18Å; R86-W88 VanDerWaalsContact C-N 3.31Å; R86-D89 PolarHBondContact O-N 3.29Å; R86-A90 PolarHBondContact O-N 3.08Å; R86-Y149 PolarHBondContact NE-OH 2.93Å; R86-S436 PolarHBondContact NH1-OG 2.89Å; R86-S436 VanDerWaalsContact NH1-OG 3.14Å; R86-L440 HydrophobicContact CG-CD1 4.42Å
87	A	90.3	Very high	88.4	Confident	18 Å²	18	33.9 Å²	33.9	15%	0.149	18%	0.175	C	C	.	.	H	α-helix	trans	-64.5	-39	173.6	0	0	0	0	0	111.3	F83 I84 A90 V91	F83-A87 VanDerWaalsContact O-CB 3.23Å; F83-A87 WeakPolarHBondContact O-CB 2.95Å; F83-A87 PolarHBondContact O-N 3.36Å; I84-A87 PolarHBondContact O-N 3.21Å; A87-A90 PolarHBondContact O-N 3.44Å; A87-V91 WeakPolarHBondContact O-CG2 3.32Å; A87-V91 PolarHBondContact O-N 2.88Å
88	W	92	Very high	87.6	Confident	118 Å²	118	34 Å²	34	45%	0.447	18%	0.177	S	C	.	.	H	α-helix	trans	-63.2	-47.2	174.5	-171.3	-99.9	0	0	0	111.5	I84 R86 A90 V91 T92 C150 T154	I84-W88 WeakPolarHBondContact O-CB 3.45Å; I84-W88 PolarHBondContact O-N 3.41Å; R86-W88 VanDerWaalsContact C-N 3.31Å; W88-A90 VanDerWaalsContact C-N 3.29Å; W88-A90 PolarHBondContact O-N 2.96Å; W88-V91 PolarHBondContact O-N 2.94Å; W88-T92 HydrophobicContact CD2-CG2 4.34Å; W88-T92 HydrophobicContact CG-CG2 4.29Å; W88-T92 HydrophobicContact CZ2-CG2 4.3Å; W88-T92 VanDerWaalsContact NE1-CG2 3.29Å; W88-T92 WeakPolarHBondContact O-CG2 3.18Å; W88-T92 PolarHBondContact O-N 2.89Å; W88-T92 PolarHBondContact O-OG1 3.23Å; W88-C150 HydrophobicContact CG-CB 4.11Å; W88-C150 PolarHBondContact NE1-O 3.34Å; W88-T154 PolarHBondContact NE1-OG1 3.15Å
89	D	89.7	Confident	86.8	Confident	5 Å²	5	38.7 Å²	38.7	3%	0.027	20%	0.202	C	C	.	.	H	α-helix	trans	-56.5	-40.4	175.4	-176.3	30.6	0	0	0	112.7	G85 R86 V91 T92 D93 Q153 K433	G85-D89 WeakPolarHBondContact O-CB 3.46Å; G85-D89 PolarHBondContact O-N 3.48Å; G85-D89 VanDerWaalsContact O-N 3.1Å; R86-D89 PolarHBondContact O-N 3.29Å; D89-V91 VanDerWaalsContact C-N 3.34Å; D89-V91 PolarHBondContact O-N 3.15Å; D89-T92 WeakPolarHBondContact CA-OG1 3.3Å; D89-T92 PolarHBondContact O-OG1 2.87Å; D89-D93 PolarHBondContact O-N 3.06Å; D89-Q153 HydrophobicContact CB-CB 4.08Å; D89-Q153 HydrophobicContact CB-CG 4.04Å; D89-K433 IonicContact OD1-NZ 2.62Å; D89-K433 PolarHBondContact OD1-NZ 3.05Å; D89-K433 WeakPolarHBondContact OD2-CD 3.24Å; D89-K433 VanDerWaalsContact OD2-CE 3.22Å; D89-K433 WeakPolarHBondContact OD2-CE 3.46Å; D89-K433 IonicContact OD2-NZ 3.08Å; D89-K433 PolarHBondContact OD2-NZ 3.15Å
90	A	88	Confident	85.8	Confident	0 Å²	0	38.9 Å²	38.9	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-61.3	-41.9	174.2	0	0	0	0	0	111.9	R86 A87 W88 P94 F430 K433 F434	R86-A90 PolarHBondContact O-N 3.08Å; A87-A90 PolarHBondContact O-N 3.44Å; W88-A90 VanDerWaalsContact C-N 3.29Å; W88-A90 PolarHBondContact O-N 2.96Å; A90-P94 WeakPolarHBondContact O-CD 3.36Å; A90-F430 HydrophobicContact CB-CD2 4.01Å; A90-F430 HydrophobicContact CB-CE2 4.12Å; A90-F430 VanDerWaalsContact O-CD2 3.24Å; A90-F430 WeakPolarHBondContact O-CD2 3.32Å; A90-K433 HydrophobicContact CB-CB 3.85Å; A90-F434 HydrophobicContact CB-CB 4.18Å
91	V	86.4	Confident	84.8	Confident	72 Å²	72	39.1 Å²	39.1	44%	0.436	21%	0.21	S	C	.	.	H	α-helix	trans	-75.8	-37.1	-178.5	175.7	0	0	0	0	112.3	A87 W88 D89 D93 P94 T95 F430	A87-V91 WeakPolarHBondContact O-CG2 3.32Å; A87-V91 PolarHBondContact O-N 2.88Å; W88-V91 PolarHBondContact O-N 2.94Å; D89-V91 VanDerWaalsContact C-N 3.34Å; D89-V91 PolarHBondContact O-N 3.15Å; V91-D93 PolarHBondContact O-N 3.02Å; V91-P94 VanDerWaalsContact O-CD 3.27Å; V91-P94 WeakPolarHBondContact O-CD 3.42Å; V91-P94 WeakPolarHBondContact O-CG 3.44Å; V91-T95 HydrophobicContact CG1-CG2 4.49Å; V91-T95 WeakPolarHBondContact O-CG2 3.43Å; V91-F430 HydrophobicContact CG2-CE2 4.34Å
92	T	87.5	Confident	83.6	Confident	7 Å²	7	48.3 Å²	48.3	4%	0.043	24%	0.244	C	C	.	.	H	α-helix	trans	-66	-38.2	-177.2	46.5	0	0	0	0	112.2	W88 D89 T95 V96 T154 T157	W88-T92 HydrophobicContact CD2-CG2 4.34Å; W88-T92 HydrophobicContact CG-CG2 4.29Å; W88-T92 HydrophobicContact CZ2-CG2 4.3Å; W88-T92 VanDerWaalsContact NE1-CG2 3.29Å; W88-T92 WeakPolarHBondContact O-CG2 3.18Å; W88-T92 PolarHBondContact O-N 2.89Å; W88-T92 PolarHBondContact O-OG1 3.23Å; D89-T92 WeakPolarHBondContact CA-OG1 3.3Å; D89-T92 PolarHBondContact O-OG1 2.87Å; T92-T95 WeakPolarHBondContact CA-OG1 3.41Å; T92-T95 PolarHBondContact O-N 3.37Å; T92-T95 VanDerWaalsContact O-N 3.16Å; T92-T95 PolarHBondContact O-OG1 3.35Å; T92-V96 WeakPolarHBondContact O-CG2 3.38Å; T92-V96 PolarHBondContact O-N 3.21Å; T92-T154 HydrophobicContact CG2-CG2 4.36Å; T92-T157 PolarHBondContact OG1-OG1 3.22Å; T92-T157 VanDerWaalsContact OG1-OG1 3.1Å
93	D	84.4	Confident	82.5	Confident	17 Å²	17	48.9 Å²	48.9	9%	0.091	25%	0.248	C	C	.	.	H	α-helix	trans	-49.8	-57.7	-179.1	-81.2	6.7	0	0	0	114.7	D89 V91 T95 G97 T157 K433	D89-D93 PolarHBondContact O-N 3.06Å; V91-D93 PolarHBondContact O-N 3.02Å; D93-T95 PolarHBondContact O-N 3.49Å; D93-G97 PolarHBondContact O-N 3.15Å; D93-T157 HydrophobicContact CB-CG2 4.43Å; D93-T157 WeakPolarHBondContact OD1-CG2 3.33Å; D93-T157 PolarHBondContact OD1-OG1 3.47Å; D93-K433 VanDerWaalsContact CG-NZ 3.31Å; D93-K433 IonicContact OD1-NZ 2.79Å; D93-K433 PolarHBondContact OD1-NZ 3.29Å; D93-K433 WeakPolarHBondContact OD2-CD 3.49Å; D93-K433 VanDerWaalsContact OD2-CE 3.28Å; D93-K433 WeakPolarHBondContact OD2-CE 3.39Å; D93-K433 IonicContact OD2-NZ 2.77Å; D93-K433 PolarHBondContact OD2-NZ 2.87Å
94	P	80.5	Confident	81.3	Confident	31 Å²	31	49 Å²	49	20%	0.201	26%	0.258	C	S	.	.	H	α-helix	trans	-67.8	-33.3	178.5	25.4	-34.3	0	0	0	112.8	A90 V91 G97 F98 F278	A90-P94 WeakPolarHBondContact O-CD 3.36Å; V91-P94 VanDerWaalsContact O-CD 3.27Å; V91-P94 WeakPolarHBondContact O-CD 3.42Å; V91-P94 WeakPolarHBondContact O-CG 3.44Å; P94-G97 PolarHBondContact O-N 3.19Å; P94-F98 PolarHBondContact O-N 3.08Å; P94-F278 HydrophobicContact CB-CZ 4.42Å
95	T	82.1	Confident	80	Confident	67 Å²	67	50.7 Å²	50.7	41%	0.411	26%	0.26	S	S	.	.	H	α-helix	trans	-66.3	-44.8	-179.9	63.5	0	0	0	0	111.8	V91 T92 D93 F98 L99	V91-T95 HydrophobicContact CG1-CG2 4.49Å; V91-T95 WeakPolarHBondContact O-CG2 3.43Å; T92-T95 WeakPolarHBondContact CA-OG1 3.41Å; T92-T95 PolarHBondContact O-N 3.37Å; T92-T95 VanDerWaalsContact O-N 3.16Å; T92-T95 PolarHBondContact O-OG1 3.35Å; D93-T95 PolarHBondContact O-N 3.49Å; T95-F98 PolarHBondContact O-N 3.23Å; T95-L99 WeakPolarHBondContact O-CG 3.29Å; T95-L99 PolarHBondContact O-N 3.5Å
96	V	80.6	Confident	79	Confident	9 Å²	9	53.1 Å²	53.1	6%	0.055	27%	0.274	C	S	.	.	H	α-helix	trans	-67.5	-40.8	175.8	172.8	0	0	0	0	110.4	T92 F98 L99 V100 T157 V161	T92-V96 WeakPolarHBondContact O-CG2 3.38Å; T92-V96 PolarHBondContact O-N 3.21Å; V96-F98 VanDerWaalsContact C-N 3.28Å; V96-F98 PolarHBondContact O-N 2.83Å; V96-L99 PolarHBondContact O-N 2.88Å; V96-L99 VanDerWaalsContact O-N 3.15Å; V96-V100 HydrophobicContact CG1-CG2 3.97Å; V96-V100 WeakPolarHBondContact O-CB 3.36Å; V96-V100 WeakPolarHBondContact O-CG2 3.16Å; V96-V100 PolarHBondContact O-N 2.9Å; V96-T157 HydrophobicContact CB-CG2 3.68Å; V96-T157 HydrophobicContact CG1-CG2 4.13Å; V96-T157 HydrophobicContact CG2-CG2 3.66Å; V96-V161 HydrophobicContact CG1-CB 4.24Å; V96-V161 HydrophobicContact CG1-CG1 4.48Å
97	G	75	Confident	77.7	Confident	25 Å²	25	63.3 Å²	63.3	26%	0.258	31%	0.313	S	S	.	.	H	α-helix	trans	-55.6	-43.8	174.2	0	0	0	0	0	112.5	D93 P94 S101	D93-G97 PolarHBondContact O-N 3.15Å; P94-G97 PolarHBondContact O-N 3.19Å; G97-S101 WeakPolarHBondContact O-CB 3.5Å; G97-S101 PolarHBondContact O-N 3.43Å
98	F	74.3	Confident	76.3	Confident	103 Å²	103	69.3 Å²	69.3	45%	0.452	34%	0.336	S	S	.	.	H	α-helix	trans	-65	-45	174.6	-178.7	-100.8	0	0	0	112.6	P94 T95 V96 V100 S101 R102	P94-F98 PolarHBondContact O-N 3.08Å; T95-F98 PolarHBondContact O-N 3.23Å; V96-F98 VanDerWaalsContact C-N 3.28Å; V96-F98 PolarHBondContact O-N 2.83Å; F98-V100 PolarHBondContact O-N 2.69Å; F98-S101 PolarHBondContact O-N 3.15Å; F98-S101 PolarHBondContact O-OG 3.16Å; F98-R102 PolarHBondContact O-N 2.84Å
99	L	74.7	Confident	75	Confident	99 Å²	99	64 Å²	64	52%	0.518	32%	0.317	S	S	.	.	H	α-helix	trans	-60.6	-46.3	178.2	-73.4	167.6	0	0	0	112.1	T95 V96 S101 R102 S103	T95-L99 WeakPolarHBondContact O-CG 3.29Å; T95-L99 PolarHBondContact O-N 3.5Å; V96-L99 PolarHBondContact O-N 2.88Å; V96-L99 VanDerWaalsContact O-N 3.15Å; L99-S101 VanDerWaalsContact C-N 3.29Å; L99-S101 PolarHBondContact O-N 2.95Å; L99-R102 PolarHBondContact O-N 2.9Å; L99-S103 PolarHBondContact O-N 3.48Å; L99-S103 VanDerWaalsContact O-N 3.16Å
100	V	71.1	Confident	73.8	Confident	13 Å²	13	66.8 Å²	66.8	8%	0.079	33%	0.328	C	S	.	.	H	α-helix	trans	-61.4	-39.5	177.6	171.5	0	0	0	0	110.8	V96 F98 R102 S103 M111 P162	V96-V100 HydrophobicContact CG1-CG2 3.97Å; V96-V100 WeakPolarHBondContact O-CB 3.36Å; V96-V100 WeakPolarHBondContact O-CG2 3.16Å; V96-V100 PolarHBondContact O-N 2.9Å; F98-V100 PolarHBondContact O-N 2.69Å; V100-R102 PolarHBondContact O-N 3.34Å; V100-S103 WeakPolarHBondContact O-CB 3.35Å; V100-S103 PolarHBondContact O-N 3.36Å; V100-S103 VanDerWaalsContact O-N 3.14Å; V100-M111 HydrophobicContact CG1-CE 3.88Å; V100-M111 HydrophobicContact CG1-SD 3.16Å; V100-M111 WeakPolarHBondContact CG1-SD 3.38Å; V100-P162 HydrophobicContact CG1-CG 4.48Å; V100-P162 HydrophobicContact CG2-CG 3.85Å
101	S	70.3	Confident	72.6	Confident	58 Å²	58	67.7 Å²	67.7	41%	0.406	33%	0.332	S	S	.	.	H	α-helix	trans	-66.1	-18.4	175.2	83.3	0	0	0	0	114.1	G97 F98 L99 R110	G97-S101 WeakPolarHBondContact O-CB 3.5Å; G97-S101 PolarHBondContact O-N 3.43Å; F98-S101 PolarHBondContact O-N 3.15Å; F98-S101 PolarHBondContact O-OG 3.16Å; L99-S101 VanDerWaalsContact C-N 3.29Å; L99-S101 PolarHBondContact O-N 2.95Å; S101-R110 PolarHBondContact O-NH2 3.41Å
102	R	68.6	Low	71.4	Confident	194 Å²	194	65 Å²	65	73%	0.732	32%	0.315	S	S	*	.	H	α-helix	trans	-98.2	-8.6	173.1	-90	-171.8	170	169.7	-1.4	113.9	F98 L99 V100	F98-R102 PolarHBondContact O-N 2.84Å; L99-R102 PolarHBondContact O-N 2.9Å; V100-R102 PolarHBondContact O-N 3.34Å
103	S	69.9	Low	69.7	Low	16 Å²	16	66.8 Å²	66.8	11%	0.112	33%	0.327	C	S	.	.	P	Polyproline II helix	trans	-64.2	135.5	-178.6	-171.9	0	0	0	0	111.6	L99 V100 R110	L99-S103 PolarHBondContact O-N 3.48Å; L99-S103 VanDerWaalsContact O-N 3.16Å; V100-S103 WeakPolarHBondContact O-CB 3.35Å; V100-S103 PolarHBondContact O-N 3.36Å; V100-S103 VanDerWaalsContact O-N 3.14Å; S103-R110 PolarHBondContact O-NE 3.14Å; S103-R110 VanDerWaalsContact O-NE 3.17Å
104	P	66.9	Low	68.1	Low	84 Å²	84	72.8 Å²	72.8	55%	0.545	35%	0.348	S	S	.	.	P	Polyproline II helix	trans	-69.2	154.6	175.2	29.5	-34.3	0	0	0	111.8
105	W	66.1	Low	66.7	Low	98 Å²	98	75.3 Å²	75.3	37%	0.371	35%	0.354	S	S	.	.	P	Polyproline II helix	trans	-64.7	133.7	168.2	-87.5	82	0	0	0	110	R110 F169 E267	W105-R110 HydrophobicContact CD2-CB 3.9Å; W105-R110 HydrophobicContact CE3-CB 4.49Å; W105-R110 HydrophobicContact CG-CB 4.02Å; W105-R110 HydrophobicContact CZ2-CB 4.31Å; W105-F169 HydrophobicContact CZ2-CD1 4.33Å; W105-F169 HydrophobicContact CZ2-CE1 4.48Å; W105-E267 HydrophobicContact CH2-CB 3.75Å; W105-E267 HydrophobicContact CH2-CG 4.1Å; W105-E267 HydrophobicContact CZ2-CB 4.03Å; W105-E267 HydrophobicContact CZ2-CG 3.84Å; W105-E267 HydrophobicContact CZ3-CB 4.16Å
106	T	70.1	Confident	65.1	Low	51 Å²	51	72.4 Å²	72.4	31%	0.313	34%	0.337	S	S	.	.	B	Isolated β-bridge	trans	-120.8	177.9	175.1	74.2	0	0	0	0	110.3	F108 G109 P113	T106-F108 PolarHBondContact O-N 3.48Å; T106-F108 VanDerWaalsContact O-N 3.11Å; T106-G109 WeakPolarHBondContact CA-O 3.44Å; T106-G109 PolarHBondContact N-O 2.77Å; T106-G109 PolarHBondContact O-N 3.03Å; T106-G109 PolarHBondContact OG1-O 3.44Å; T106-P113 WeakPolarHBondContact OG1-CB 3.49Å; T106-P113 WeakPolarHBondContact OG1-CG 3.4Å
107	R	62.8	Low	63.9	Low	245 Å²	245	73.5 Å²	73.5	93%	0.925	34%	0.342	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.9	-23.7	-174.6	-57.8	-172.3	-151.3	175.1	6.8	114.7
108	F	61.7	Low	62.8	Low	143 Å²	143	80 Å²	80	63%	0.627	37%	0.37	S	S	*	.	T	Hydrogen-bonded Turn	trans	-102.5	8.3	179.8	-65.2	-79.4	0	0	0	112.3	T106 P113	T106-F108 PolarHBondContact O-N 3.48Å; T106-F108 VanDerWaalsContact O-N 3.11Å; F108-P113 HydrophobicContact CB-CB 3.89Å; F108-P113 HydrophobicContact CB-CG 3.35Å; F108-P113 WeakPolarHBondContact O-CG 3.25Å
109	G	64	Low	62.5	Low	6 Å²	6	80.8 Å²	80.8	6%	0.062	38%	0.379	C	S	.	.	B	Isolated β-bridge	trans	114.6	-171.5	-173.4	0	0	0	0	0	114.1	T106 P113 E265	T106-G109 WeakPolarHBondContact CA-O 3.44Å; T106-G109 PolarHBondContact N-O 2.77Å; T106-G109 PolarHBondContact O-N 3.03Å; T106-G109 PolarHBondContact OG1-O 3.44Å; G109-P113 VanDerWaalsContact C-CD 3.48Å; G109-P113 VanDerWaalsContact O-CD 3.27Å; G109-P113 WeakPolarHBondContact O-CD 3.11Å; G109-P113 WeakPolarHBondContact O-CG 3.36Å; G109-E265 WeakPolarHBondContact CA-OE2 3.28Å
110	R	64.4	Low	62.7	Low	65 Å²	65	76.2 Å²	76.2	25%	0.245	36%	0.355	C	S	.	.	S	Bend	trans	-99.4	-35.1	174.3	-177.2	175.3	173.2	-166.1	-0.5	112.5	S101 S103 W105 E265	S101-R110 PolarHBondContact O-NH2 3.41Å; S103-R110 PolarHBondContact O-NE 3.14Å; S103-R110 VanDerWaalsContact O-NE 3.17Å; W105-R110 HydrophobicContact CD2-CB 3.9Å; W105-R110 HydrophobicContact CE3-CB 4.49Å; W105-R110 HydrophobicContact CG-CB 4.02Å; W105-R110 HydrophobicContact CZ2-CB 4.31Å; R110-E265 PolarHBondContact N-OE2 2.59Å
111	M	63.6	Low	63.3	Low	19 Å²	19	75.8 Å²	75.8	9%	0.094	35%	0.352	C	S	.	.	S	Bend	trans	-95.9	-38.2	-173.5	-52.8	-58.6	-152.9	0	0	113	V100 P162 A165 L166 F169 E265	V100-M111 HydrophobicContact CG1-CE 3.88Å; V100-M111 HydrophobicContact CG1-SD 3.16Å; V100-M111 WeakPolarHBondContact CG1-SD 3.38Å; M111-P162 HydrophobicContact CB-CB 4.26Å; M111-A165 HydrophobicContact CE-CB 3.96Å; M111-L166 HydrophobicContact CB-CD1 4.29Å; M111-F169 HydrophobicContact CE-CD2 4.12Å; M111-F169 HydrophobicContact CE-CE2 3.3Å; M111-F169 HydrophobicContact CE-CZ 3.84Å; M111-F169 HydrophobicContact CG-CD2 4.01Å; M111-F169 HydrophobicContact CG-CE2 4.12Å; M111-E265 WeakPolarHBondContact CA-OE1 3.18Å; M111-E265 WeakPolarHBondContact CB-OE1 3.42Å; M111-E265 PolarHBondContact N-OE1 3.25Å; M111-E265 VanDerWaalsContact N-OE1 3.1Å; M111-E265 PolarHBondContact N-OE2 3.25Å; M111-E265 VanDerWaalsContact N-OE2 3.17Å
112	M	60.7	Low	64.1	Low	16 Å²	16	75.8 Å²	75.8	8%	0.079	35%	0.351	C	S	.	.	S	Bend	trans	-66.1	-38.5	178.4	-80	-71.7	-134.3	0	0	114.2	I117 L166 V263 E265	M112-I117 HydrophobicContact SD-CD1 3.73Å; M112-L166 HydrophobicContact CE-CD2 4.39Å; M112-L166 HydrophobicContact CG-CD1 4.21Å; M112-L166 HydrophobicContact SD-CD2 4.44Å; M112-V263 HydrophobicContact CE-CB 3.93Å; M112-V263 HydrophobicContact CE-CG1 4.31Å; M112-V263 WeakPolarHBondContact CE-O 3.14Å; M112-E265 WeakPolarHBondContact CA-OE1 3.35Å; M112-E265 VanDerWaalsContact CB-OE1 3.23Å; M112-E265 WeakPolarHBondContact CB-OE1 3.24Å; M112-E265 HydrophobicContact CG-CG 3.92Å; M112-E265 WeakPolarHBondContact CG-OE1 3.26Å; M112-E265 PolarHBondContact N-OE1 3.34Å
113	P	52.3	Low	65.1	Low	44 Å²	44	72.3 Å²	72.3	29%	0.286	34%	0.341	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.1	-16.1	-160.1	-20.7	43.2	0	0	0	116.2	T106 F108 G109	T106-P113 WeakPolarHBondContact OG1-CB 3.49Å; T106-P113 WeakPolarHBondContact OG1-CG 3.4Å; F108-P113 HydrophobicContact CB-CB 3.89Å; F108-P113 HydrophobicContact CB-CG 3.35Å; F108-P113 WeakPolarHBondContact O-CG 3.25Å; G109-P113 VanDerWaalsContact C-CD 3.48Å; G109-P113 VanDerWaalsContact O-CD 3.27Å; G109-P113 WeakPolarHBondContact O-CD 3.11Å; G109-P113 WeakPolarHBondContact O-CG 3.36Å
114	W	51.5	Low	66	Low	143 Å²	143	71.5 Å²	71.5	54%	0.542	34%	0.336	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94	-22.1	-167.3	-127.9	87.7	0	0	0	115.5
115	Y	49.6	Very low	67.2	Low	83 Å²	83	68.7 Å²	68.7	33%	0.325	32%	0.317	S	S	.	.	T	Hydrogen-bonded Turn	trans	-142.6	-34.1	-176.1	-84.3	-78.3	0	0	0	115.1	S120 C158	Y115-S120 WeakPolarHBondContact O-CA 3.23Å; Y115-S120 WeakPolarHBondContact O-CB 3.43Å; Y115-S120 PolarHBondContact O-N 2.85Å; Y115-C158 HydrophobicContact CD1-CB 4.26Å; Y115-C158 HydrophobicContact CG-CB 4.43Å
116	A	49.3	Very low	68.5	Low	6 Å²	6	69.3 Å²	69.3	5%	0.05	33%	0.325	C	S	.	.	I	π-helix	trans	-80.8	-38.2	-152.9	0	0	0	0	0	116.6	T121 F159	A116-T121 WeakPolarHBondContact O-CB 3.19Å; A116-T121 PolarHBondContact O-OG1 3.27Å; A116-F159 HydrophobicContact CB-CD2 4.09Å
117	I	54.9	Low	69.6	Low	33 Å²	33	67 Å²	67	17%	0.169	31%	0.311	C	S	.	.	I	π-helix	trans	-108.6	-30.3	-164.3	-68.6	130.4	0	0	0	115.4	M112 F260	M112-I117 HydrophobicContact SD-CD1 3.73Å; I117-F260 HydrophobicContact CB-CB 4.47Å; I117-F260 HydrophobicContact CB-CD2 4.19Å; I117-F260 HydrophobicContact CB-CG 4.42Å; I117-F260 HydrophobicContact CD1-CB 3.73Å; I117-F260 HydrophobicContact CD1-CD2 3.46Å; I117-F260 VanDerWaalsContact CD1-CD2 3.46Å; I117-F260 HydrophobicContact CD1-CE2 4.46Å; I117-F260 HydrophobicContact CD1-CG 3.99Å; I117-F260 HydrophobicContact CG1-CB 3.97Å; I117-F260 HydrophobicContact CG1-CD2 4.17Å; I117-F260 HydrophobicContact CG1-CG 4.36Å; I117-F260 HydrophobicContact CG2-CB 3.88Å; I117-F260 HydrophobicContact CG2-CD1 4.31Å; I117-F260 HydrophobicContact CG2-CD2 3.99Å; I117-F260 HydrophobicContact CG2-CG 3.79Å
118	L	52.8	Low	71	Confident	161 Å²	161	55.5 Å²	55.5	84%	0.843	27%	0.268	S	S	*	.	I	π-helix	trans	-107.2	-31.3	-179.1	-149.2	81.6	0	0	0	115.1	P122	L118-P122 WeakPolarHBondContact O-CD 3.46Å; L118-P122 WeakPolarHBondContact O-CG 3.45Å
119	L	67.2	Low	72.6	Confident	120 Å²	120	52 Å²	52	63%	0.628	25%	0.252	S	S	*	.	I	π-helix	trans	-109.7	-38.9	-177.4	-158.3	76.5	0	0	0	113.7	F123	L119-F123 HydrophobicContact CD1-CD2 4.49Å; L119-F123 HydrophobicContact CD1-CE2 3.82Å; L119-F123 HydrophobicContact CG-CE2 4.33Å; L119-F123 WeakPolarHBondContact O-CD2 3.39Å
120	S	78.1	Confident	73.9	Confident	2 Å²	2	53.3 Å²	53.3	1%	0.014	26%	0.258	C	S	.	.	I	π-helix	trans	-77.7	-49.8	177.8	-166.6	0	0	0	0	112.2	Y115 F123 A124 L155	Y115-S120 WeakPolarHBondContact O-CA 3.23Å; Y115-S120 WeakPolarHBondContact O-CB 3.43Å; Y115-S120 PolarHBondContact O-N 2.85Å; S120-F123 PolarHBondContact O-N 2.97Å; S120-A124 VanDerWaalsContact O-CB 3.29Å; S120-A124 WeakPolarHBondContact O-CB 3.2Å; S120-A124 PolarHBondContact O-N 3.11Å; S120-L155 WeakPolarHBondContact OG-CA 3.14Å; S120-L155 WeakPolarHBondContact OG-CB 3.42Å; S120-L155 PolarHBondContact OG-O 3.26Å
121	T	83.8	Confident	75.3	Confident	5 Å²	5	50.3 Å²	50.3	3%	0.031	25%	0.247	C	C	.	.	H	α-helix	trans	-53.2	-52.9	-175.1	-70.2	0	0	0	0	114.2	A116 F123 A124 V125 Y252 V253 A256	A116-T121 WeakPolarHBondContact O-CB 3.19Å; A116-T121 PolarHBondContact O-OG1 3.27Å; T121-F123 VanDerWaalsContact C-N 3.33Å; T121-F123 PolarHBondContact O-N 3.34Å; T121-A124 PolarHBondContact O-N 3.43Å; T121-V125 HydrophobicContact CG2-CG2 4.33Å; T121-V125 WeakPolarHBondContact O-CB 3.49Å; T121-V125 WeakPolarHBondContact O-CG2 3.33Å; T121-V125 PolarHBondContact O-N 2.96Å; T121-Y252 HydrophobicContact CG2-CD1 3.88Å; T121-Y252 HydrophobicContact CG2-CE1 3.93Å; T121-V253 HydrophobicContact CG2-CG2 4.42Å; T121-A256 HydrophobicContact CG2-CB 3.88Å
122	P	87.1	Confident	76.6	Confident	58 Å²	58	49.4 Å²	49.4	38%	0.377	24%	0.242	S	C	.	.	H	α-helix	trans	-66.5	-34	-178.4	23.6	-30.9	0	0	0	112.8	L118 M126	L118-P122 WeakPolarHBondContact O-CD 3.46Å; L118-P122 WeakPolarHBondContact O-CG 3.45Å; P122-M126 WeakPolarHBondContact O-CB 3.36Å; P122-M126 PolarHBondContact O-N 2.69Å
123	F	89.4	Confident	78	Confident	120 Å²	120	52.9 Å²	52.9	53%	0.526	26%	0.255	S	S	.	.	H	α-helix	trans	-75.1	-32.6	176.3	-74	-96.4	0	0	0	112.2	L119 S120 T121 M126 S127 L155	L119-F123 HydrophobicContact CD1-CD2 4.49Å; L119-F123 HydrophobicContact CD1-CE2 3.82Å; L119-F123 HydrophobicContact CG-CE2 4.33Å; L119-F123 WeakPolarHBondContact O-CD2 3.39Å; S120-F123 PolarHBondContact O-N 2.97Å; T121-F123 VanDerWaalsContact C-N 3.33Å; T121-F123 PolarHBondContact O-N 3.34Å; F123-M126 PolarHBondContact O-N 3.3Å; F123-S127 WeakPolarHBondContact O-CB 3.23Å; F123-S127 PolarHBondContact O-N 2.89Å; F123-S127 PolarHBondContact O-OG 3.4Å; F123-L155 VanDerWaalsContact C-CD1 3.48Å; F123-L155 HydrophobicContact CB-CD1 3.67Å; F123-L155 HydrophobicContact CB-CD2 4.44Å
124	A	90.1	Very high	79.7	Confident	0 Å²	0	51.6 Å²	51.6	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-65.2	-45.9	174.2	0	0	0	0	0	110	S120 T121 S127 Y128 F152 L155	S120-A124 VanDerWaalsContact O-CB 3.29Å; S120-A124 WeakPolarHBondContact O-CB 3.2Å; S120-A124 PolarHBondContact O-N 3.11Å; T121-A124 PolarHBondContact O-N 3.43Å; A124-S127 WeakPolarHBondContact CA-OG 3.3Å; A124-S127 PolarHBondContact O-N 3.28Å; A124-S127 PolarHBondContact O-OG 3.47Å; A124-Y128 WeakPolarHBondContact O-CB 3.17Å; A124-Y128 PolarHBondContact O-N 3.46Å; A124-F152 WeakPolarHBondContact O-CD2 3.49Å; A124-L155 HydrophobicContact CB-CB 3.82Å
125	V	91.9	Very high	81.3	Confident	24 Å²	24	45 Å²	45	15%	0.145	22%	0.222	C	C	.	.	H	α-helix	trans	-62.5	-43.7	176.2	170	0	0	0	0	111.1	T121 F129 C249 Y252 V253	T121-V125 HydrophobicContact CG2-CG2 4.33Å; T121-V125 WeakPolarHBondContact O-CB 3.49Å; T121-V125 WeakPolarHBondContact O-CG2 3.33Å; T121-V125 PolarHBondContact O-N 2.96Å; V125-F129 PolarHBondContact O-N 3.35Å; V125-C249 HydrophobicContact CG1-CB 3.53Å; V125-C249 PolarHBondContact O-SG 3.39Å; V125-Y252 HydrophobicContact CG2-CD1 3.93Å; V125-Y252 HydrophobicContact CG2-CG 3.92Å; V125-V253 HydrophobicContact CG1-CG2 4.29Å; V125-V253 HydrophobicContact CG2-CG2 3.82Å
126	M	92.6	Very high	82.7	Confident	111 Å²	111	46.3 Å²	46.3	55%	0.547	24%	0.241	S	C	.	.	H	α-helix	trans	-63.7	-48.4	175.9	-173.9	64.9	71.2	0	0	111.9	P122 F123 Y128 F129 L130	P122-M126 WeakPolarHBondContact O-CB 3.36Å; P122-M126 PolarHBondContact O-N 2.69Å; F123-M126 PolarHBondContact O-N 3.3Å; M126-Y128 PolarHBondContact O-N 2.97Å; M126-F129 PolarHBondContact O-N 2.98Å; M126-L130 HydrophobicContact CG-CD1 3.95Å; M126-L130 VanDerWaalsContact O-CG 3.25Å; M126-L130 WeakPolarHBondContact O-CG 3.23Å; M126-L130 PolarHBondContact O-N 2.97Å; M126-L130 HydrophobicContact SD-CD1 4.46Å
127	S	92.8	Very high	84.3	Confident	3 Å²	3	50 Å²	50	2%	0.021	26%	0.256	C	S	.	.	H	α-helix	trans	-64	-39.4	179.2	52.1	0	0	0	0	112.2	F123 A124 F129 L130 I131 F152	F123-S127 WeakPolarHBondContact O-CB 3.23Å; F123-S127 PolarHBondContact O-N 2.89Å; F123-S127 PolarHBondContact O-OG 3.4Å; A124-S127 WeakPolarHBondContact CA-OG 3.3Å; A124-S127 PolarHBondContact O-N 3.28Å; A124-S127 PolarHBondContact O-OG 3.47Å; S127-F129 PolarHBondContact O-N 3.47Å; S127-L130 PolarHBondContact O-N 3.25Å; S127-I131 WeakPolarHBondContact O-CG1 3.16Å; S127-I131 PolarHBondContact O-N 2.84Å; S127-I131 VanDerWaalsContact O-N 3.09Å; S127-F152 WeakPolarHBondContact OG-CA 2.93Å
128	Y	94.2	Very high	85.3	Confident	3 Å²	3	54.8 Å²	54.8	1%	0.012	28%	0.278	C	S	.	.	H	α-helix	trans	-59.4	-47.2	173.3	-174.5	-101.5	0	0	0	111.8	T55 A58 L59 A124 M126 L130 I131 W132 F152 I248	T55-Y128 HydrophobicContact CG2-CD2 4.04Å; T55-Y128 HydrophobicContact CG2-CE2 3.86Å; T55-Y128 HydrophobicContact CG2-CG 4.49Å; A58-Y128 VanDerWaalsContact CB-OH 3.23Å; A58-Y128 WeakPolarHBondContact CB-OH 3.36Å; L59-Y128 HydrophobicContact CD1-CE2 4.34Å; L59-Y128 HydrophobicContact CD2-CE2 4.2Å; L59-Y128 HydrophobicContact CG-CE2 4.16Å; A124-Y128 WeakPolarHBondContact O-CB 3.17Å; A124-Y128 PolarHBondContact O-N 3.46Å; M126-Y128 PolarHBondContact O-N 2.97Å; Y128-L130 VanDerWaalsContact C-N 3.28Å; Y128-L130 PolarHBondContact O-N 3.08Å; Y128-I131 WeakPolarHBondContact O-CB 3.49Å; Y128-I131 PolarHBondContact O-N 3.06Å; Y128-W132 AromaticContact CE1-CD1 3.86Å; Y128-W132 AromaticContact CE1-NE1 3.49Å; Y128-W132 AromaticContact CE2-NE1 3.52Å; Y128-W132 AromaticContact CZ-NE1 3.18Å; Y128-W132 PolarHBondContact OH-NE1 3.28Å; Y128-F152 HydrophobicContact CD2-CD2 4.16Å; Y128-F152 HydrophobicContact CD2-CE1 4.18Å; Y128-F152 AromaticContact CD2-CE2 3.71Å; Y128-F152 HydrophobicContact CD2-CE2 3.71Å; Y128-F152 AromaticContact CD2-CZ 3.73Å; Y128-F152 HydrophobicContact CD2-CZ 3.73Å; Y128-F152 HydrophobicContact CE2-CZ 4.44Å; Y128-F152 HydrophobicContact CG-CD2 4.43Å; Y128-F152 HydrophobicContact CG-CE2 4.08Å; Y128-I248 HydrophobicContact CD1-CG2 4.41Å; Y128-I248 HydrophobicContact CE1-CB 4.02Å; Y128-I248 HydrophobicContact CE1-CD1 4.42Å; Y128-I248 HydrophobicContact CE1-CG2 3.67Å; Y128-I248 WeakPolarHBondContact OH-CD1 3.22Å
129	F	93.9	Very high	86.3	Confident	69 Å²	69	56.2 Å²	56.2	30%	0.303	28%	0.279	S	S	.	.	H	α-helix	trans	-59.6	-39.5	176.1	-175.8	-98.4	0	0	0	112	V125 M126 S127 I131 W132 Y133 M242 S245 A246	V125-F129 PolarHBondContact O-N 3.35Å; M126-F129 PolarHBondContact O-N 2.98Å; S127-F129 PolarHBondContact O-N 3.47Å; F129-I131 VanDerWaalsContact C-N 3.3Å; F129-I131 PolarHBondContact O-N 3.01Å; F129-W132 PolarHBondContact O-N 3.27Å; F129-W132 VanDerWaalsContact O-N 3.15Å; F129-Y133 PolarHBondContact O-N 2.87Å; F129-M242 HydrophobicContact CE2-CB 4.29Å; F129-M242 HydrophobicContact CZ-CB 4.46Å; F129-S245 VanDerWaalsContact CD2-OG 3.27Å; F129-S245 WeakPolarHBondContact CD2-OG 3.49Å; F129-A246 HydrophobicContact CE2-CB 4.28Å
130	L	92.3	Very high	87.1	Confident	35 Å²	35	51.6 Å²	51.6	18%	0.183	26%	0.261	C	S	.	.	H	α-helix	trans	-70.5	-20.8	179.5	-67.2	167.4	0	0	0	113.9	M126 S127 Y128 W132 W144 F148	M126-L130 HydrophobicContact CG-CD1 3.95Å; M126-L130 VanDerWaalsContact O-CG 3.25Å; M126-L130 WeakPolarHBondContact O-CG 3.23Å; M126-L130 PolarHBondContact O-N 2.97Å; M126-L130 HydrophobicContact SD-CD1 4.46Å; S127-L130 PolarHBondContact O-N 3.25Å; Y128-L130 VanDerWaalsContact C-N 3.28Å; Y128-L130 PolarHBondContact O-N 3.08Å; L130-W132 VanDerWaalsContact C-N 3.33Å; L130-W144 HydrophobicContact CB-CZ2 4.29Å; L130-W144 HydrophobicContact CD2-CH2 4.39Å; L130-W144 HydrophobicContact CD2-CZ2 3.89Å; L130-W144 PolarHBondContact O-NE1 3.48Å; L130-F148 HydrophobicContact CB-CD1 3.79Å; L130-F148 HydrophobicContact CB-CD2 4.36Å; L130-F148 HydrophobicContact CB-CE1 4.07Å; L130-F148 HydrophobicContact CB-CG 3.95Å; L130-F148 HydrophobicContact CB-CZ 4.47Å; L130-F148 HydrophobicContact CD1-CD1 3.77Å; L130-F148 HydrophobicContact CD1-CE1 3.24Å; L130-F148 HydrophobicContact CD1-CZ 3.72Å; L130-F148 HydrophobicContact CG-CD1 4.43Å; L130-F148 HydrophobicContact CG-CE1 4.26Å
131	I	92.4	Very high	87.6	Confident	2 Å²	2	52.1 Å²	52.1	1%	0.01	26%	0.263	C	S	.	.	H	α-helix	trans	-68	-34.2	170.2	-67	166.7	0	0	0	111	L59 L63 S127 Y128 F129 Y145 F148 Y149 F152	L59-I131 HydrophobicContact CD2-CG2 4.25Å; L63-I131 HydrophobicContact CD1-CG2 3.78Å; S127-I131 WeakPolarHBondContact O-CG1 3.16Å; S127-I131 PolarHBondContact O-N 2.84Å; S127-I131 VanDerWaalsContact O-N 3.09Å; Y128-I131 WeakPolarHBondContact O-CB 3.49Å; Y128-I131 PolarHBondContact O-N 3.06Å; F129-I131 VanDerWaalsContact C-N 3.3Å; F129-I131 PolarHBondContact O-N 3.01Å; I131-Y145 VanDerWaalsContact O-CE1 3.28Å; I131-Y145 WeakPolarHBondContact O-CE1 3.41Å; I131-F148 HydrophobicContact CG1-CB 4.05Å; I131-Y149 HydrophobicContact CD1-CD2 4.16Å; I131-F152 HydrophobicContact CD1-CB 3.73Å; I131-F152 HydrophobicContact CD1-CD1 4.1Å; I131-F152 HydrophobicContact CD1-CG 3.95Å
132	W	91.7	Very high	87.9	Confident	0 Å²	0	53.3 Å²	53.3	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-91.6	-4	179.8	-58.5	101.1	0	0	0	113.2	L59 F62 Y66 Y128 F129 L130 Y241	L59-W132 HydrophobicContact CD2-CZ2 3.89Å; F62-W132 HydrophobicContact CB-CH2 3.88Å; F62-W132 HydrophobicContact CB-CZ3 4.38Å; Y66-W132 HydrophobicContact CD1-CE3 4.22Å; Y66-W132 HydrophobicContact CD1-CZ3 4.35Å; Y66-W132 AromaticContact CD2-CE3 3.71Å; Y66-W132 HydrophobicContact CD2-CE3 3.71Å; Y66-W132 AromaticContact CD2-CZ3 3.96Å; Y66-W132 HydrophobicContact CD2-CZ3 3.96Å; Y66-W132 HydrophobicContact CE2-CE3 4.03Å; Y66-W132 AromaticContact CG-CE3 3.81Å; Y66-W132 HydrophobicContact CG-CE3 3.81Å; Y66-W132 AromaticContact CG-CZ3 3.75Å; Y66-W132 HydrophobicContact CG-CZ3 3.75Å; Y66-W132 PolarHBondContact OH-O 2.83Å; Y128-W132 AromaticContact CE1-CD1 3.86Å; Y128-W132 AromaticContact CE1-NE1 3.49Å; Y128-W132 AromaticContact CE2-NE1 3.52Å; Y128-W132 AromaticContact CZ-NE1 3.18Å; Y128-W132 PolarHBondContact OH-NE1 3.28Å; F129-W132 PolarHBondContact O-N 3.27Å; F129-W132 VanDerWaalsContact O-N 3.15Å; L130-W132 VanDerWaalsContact C-N 3.33Å; W132-Y241 HydrophobicContact CD2-CD1 4.35Å; W132-Y241 AromaticContact CE3-CD1 3.35Å; W132-Y241 HydrophobicContact CE3-CD1 3.35Å; W132-Y241 AromaticContact CE3-CE1 3.99Å; W132-Y241 HydrophobicContact CE3-CE1 3.99Å; W132-Y241 HydrophobicContact CE3-CG 4.1Å; W132-Y241 HydrophobicContact CH2-CD1 4.36Å; W132-Y241 HydrophobicContact CH2-CE1 4.34Å; W132-Y241 AromaticContact CZ3-CD1 3.36Å; W132-Y241 HydrophobicContact CZ3-CD1 3.36Å; W132-Y241 AromaticContact CZ3-CE1 3.49Å; W132-Y241 HydrophobicContact CZ3-CE1 3.49Å; W132-Y241 VanDerWaalsContact CZ3-CE1 3.49Å; W132-Y241 HydrophobicContact CZ3-CG 4.43Å
133	Y	90.6	Very high	88.1	Confident	88 Å²	88	56.4 Å²	56.4	35%	0.345	28%	0.283	S	S	.	.	S	Bend	trans	-84.7	130.3	171.3	-179.1	-103.7	0	0	0	110.7	F129 P135 W144 M242	F129-Y133 PolarHBondContact O-N 2.87Å; Y133-P135 WeakPolarHBondContact O-CD 3.28Å; Y133-W144 HydrophobicContact CD1-CZ2 4.28Å; Y133-M242 HydrophobicContact CD2-SD 3.79Å
134	V	87	Confident	88.3	Confident	18 Å²	18	53.6 Å²	53.6	11%	0.109	27%	0.268	C	S	.	.			trans	-87.3	113.3	174.2	-177.6	0	0	0	0	108.7	Y66 V70 R238	Y66-V134 WeakPolarHBondContact OH-CG2 3.26Å; V70-V134 HydrophobicContact CG1-CG2 4.3Å; V134-R238 HydrophobicContact CG2-CG 4.05Å
135	P	85.3	Confident	88.4	Confident	3 Å²	3	53.7 Å²	53.7	2%	0.019	27%	0.269	C	S	.	.			trans	-63.9	144.6	179.1	24.3	-32.6	0	0	0	111.7	Y133 F137 K141 W144	Y133-P135 WeakPolarHBondContact O-CD 3.28Å; P135-F137 VanDerWaalsContact C-N 3.26Å; P135-F137 HydrophobicContact CB-CD1 3.94Å; P135-F137 HydrophobicContact CB-CD2 4.35Å; P135-F137 HydrophobicContact CB-CE1 3.42Å; P135-F137 VanDerWaalsContact CB-CE1 3.42Å; P135-F137 HydrophobicContact CB-CE2 3.88Å; P135-F137 HydrophobicContact CB-CG 4.37Å; P135-F137 HydrophobicContact CB-CZ 3.38Å; P135-F137 HydrophobicContact CG-CE2 4.18Å; P135-F137 HydrophobicContact CG-CZ 4.05Å; P135-F137 PolarHBondContact O-N 2.89Å; P135-K141 HydrophobicContact CG-CB 4.46Å; P135-K141 HydrophobicContact CG-CG 4.12Å; P135-W144 HydrophobicContact CB-CD2 4.24Å; P135-W144 HydrophobicContact CB-CG 4.3Å; P135-W144 HydrophobicContact CG-CB 4.31Å; P135-W144 HydrophobicContact CG-CD2 4.41Å; P135-W144 HydrophobicContact CG-CG 3.95Å
136	P	78.8	Confident	88.5	Confident	111 Å²	111	54.5 Å²	54.5	72%	0.721	27%	0.272	S	S	*	.	S	Bend	trans	-75.5	-10.2	-177.3	30	-35.4	0	0	0	114.1
137	F	83.6	Confident	88.6	Confident	84 Å²	84	53.4 Å²	53.4	37%	0.368	27%	0.268	S	S	.	.			trans	-93.7	136.8	179	50.7	-94.1	0	0	0	111.5	P135 K141 W144	P135-F137 VanDerWaalsContact C-N 3.26Å; P135-F137 HydrophobicContact CB-CD1 3.94Å; P135-F137 HydrophobicContact CB-CD2 4.35Å; P135-F137 HydrophobicContact CB-CE1 3.42Å; P135-F137 VanDerWaalsContact CB-CE1 3.42Å; P135-F137 HydrophobicContact CB-CE2 3.88Å; P135-F137 HydrophobicContact CB-CG 4.37Å; P135-F137 HydrophobicContact CB-CZ 3.38Å; P135-F137 HydrophobicContact CG-CE2 4.18Å; P135-F137 HydrophobicContact CG-CZ 4.05Å; P135-F137 PolarHBondContact O-N 2.89Å; F137-K141 VanDerWaalsContact O-CE 3.25Å; F137-K141 WeakPolarHBondContact O-CE 3.14Å; F137-K141 WeakPolarHBondContact O-CG 3.37Å; F137-W144 HydrophobicContact CE1-CE3 4.03Å; F137-W144 HydrophobicContact CE1-CZ3 4.32Å; F137-W144 HydrophobicContact CE2-CB 4.18Å; F137-W144 HydrophobicContact CZ-CB 4.03Å; F137-W144 AromaticContact CZ-CD2 3.91Å; F137-W144 HydrophobicContact CZ-CD2 3.91Å; F137-W144 AromaticContact CZ-CE3 3.49Å; F137-W144 HydrophobicContact CZ-CE3 3.49Å; F137-W144 VanDerWaalsContact CZ-CE3 3.49Å; F137-W144 HydrophobicContact CZ-CG 4.18Å; F137-W144 HydrophobicContact CZ-CZ3 4.23Å
138	E	75.9	Confident	88.6	Confident	134 Å²	134	54.9 Å²	54.9	63%	0.626	27%	0.274	S	S	*	.	S	Bend	trans	-81	-46.8	177.6	-68.2	-62.8	147.9	0	0	112.2	G140 K141	E138-G140 PolarHBondContact O-N 3.26Å; E138-G140 VanDerWaalsContact O-N 3.09Å; E138-K141 IonicContact OE1-NZ 2.65Å; E138-K141 PolarHBondContact OE1-NZ 2.75Å; E138-K141 WeakPolarHBondContact OE2-CE 3.21Å; E138-K141 IonicContact OE2-NZ 3.3Å; E138-K141 PolarHBondContact OE2-NZ 3.15Å
139	H	74.5	Confident	88.6	Confident	190 Å²	190	54.9 Å²	54.9	88%	0.88	27%	0.274	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.8	89.6	178.2	-58.2	-39.1	0	0	0	110.1
140	G	83.4	Confident	88.6	Confident	24 Å²	24	52.5 Å²	52.5	25%	0.247	27%	0.266	C	S	.	.	T	Hydrogen-bonded Turn	trans	139.1	-4.1	177.2	0	0	0	0	0	115.3	E138 V142 I143 W144	E138-G140 PolarHBondContact O-N 3.26Å; E138-G140 VanDerWaalsContact O-N 3.09Å; G140-V142 PolarHBondContact O-N 2.79Å; G140-I143 PolarHBondContact O-N 2.91Å; G140-I143 VanDerWaalsContact O-N 3.1Å; G140-W144 PolarHBondContact O-N 3.12Å
141	K	87.8	Confident	88.7	Confident	12 Å²	12	53.6 Å²	53.6	5%	0.052	27%	0.274	C	S	.	.	H	α-helix	trans	-51.5	-42.6	179.9	-63.8	-172.6	171.2	161.5	0	112.7	L73 P135 F137 E138 W144 Y145	L73-K141 HydrophobicContact CD2-CB 4.06Å; P135-K141 HydrophobicContact CG-CB 4.46Å; P135-K141 HydrophobicContact CG-CG 4.12Å; F137-K141 VanDerWaalsContact O-CE 3.25Å; F137-K141 WeakPolarHBondContact O-CE 3.14Å; F137-K141 WeakPolarHBondContact O-CG 3.37Å; E138-K141 IonicContact OE1-NZ 2.65Å; E138-K141 PolarHBondContact OE1-NZ 2.75Å; E138-K141 WeakPolarHBondContact OE2-CE 3.21Å; E138-K141 IonicContact OE2-NZ 3.3Å; E138-K141 PolarHBondContact OE2-NZ 3.15Å; K141-W144 WeakPolarHBondContact O-CB 3.38Å; K141-W144 PolarHBondContact O-N 3.05Å; K141-Y145 HydrophobicContact CB-CE2 4.44Å; K141-Y145 WeakPolarHBondContact O-CD2 3.2Å; K141-Y145 PolarHBondContact O-N 3.35Å
142	V	90.6	Very high	88.7	Confident	31 Å²	31	53.6 Å²	53.6	19%	0.188	27%	0.273	C	S	.	.	H	α-helix	trans	-62.5	-47.3	-179.9	-177.2	0	0	0	0	111.3	L73 Y77 I81 G140 W144 Y145 I146	L73-V142 HydrophobicContact CD2-CG2 4.14Å; Y77-V142 HydrophobicContact CD1-CG1 4.08Å; Y77-V142 HydrophobicContact CD1-CG2 3.8Å; Y77-V142 HydrophobicContact CD2-CG2 4.34Å; Y77-V142 HydrophobicContact CE1-CG2 4.48Å; Y77-V142 HydrophobicContact CG-CG2 3.71Å; I81-V142 HydrophobicContact CD1-CG1 4.3Å; I81-V142 HydrophobicContact CG1-CG1 4.29Å; G140-V142 PolarHBondContact O-N 2.79Å; V142-W144 VanDerWaalsContact C-N 3.29Å; V142-W144 PolarHBondContact O-N 3.4Å; V142-Y145 PolarHBondContact O-N 3.46Å; V142-I146 HydrophobicContact CG1-CD1 3.92Å; V142-I146 WeakPolarHBondContact O-CG1 3.36Å; V142-I146 PolarHBondContact O-N 3.45Å
143	I	91.6	Very high	88.7	Confident	123 Å²	123	54 Å²	54	63%	0.631	28%	0.276	S	S	*	.	H	α-helix	trans	-63.1	-39.7	179.2	-61.2	172.8	0	0	0	110.3	G140 I146 L147	G140-I143 PolarHBondContact O-N 2.91Å; G140-I143 VanDerWaalsContact O-N 3.1Å; I143-I146 PolarHBondContact O-N 3.47Å; I143-L147 VanDerWaalsContact O-CB 3.24Å; I143-L147 WeakPolarHBondContact O-CB 3.15Å; I143-L147 PolarHBondContact O-N 3.44Å
144	W	92.8	Very high	88.7	Confident	60 Å²	60	52 Å²	52	23%	0.227	27%	0.272	C	S	.	.	H	α-helix	trans	-57.3	-53.3	174.9	178.8	-85	0	0	0	111.7	L130 Y133 P135 F137 G140 K141 V142 I146 L147 F148	L130-W144 HydrophobicContact CB-CZ2 4.29Å; L130-W144 HydrophobicContact CD2-CH2 4.39Å; L130-W144 HydrophobicContact CD2-CZ2 3.89Å; L130-W144 PolarHBondContact O-NE1 3.48Å; Y133-W144 HydrophobicContact CD1-CZ2 4.28Å; P135-W144 HydrophobicContact CB-CD2 4.24Å; P135-W144 HydrophobicContact CB-CG 4.3Å; P135-W144 HydrophobicContact CG-CB 4.31Å; P135-W144 HydrophobicContact CG-CD2 4.41Å; P135-W144 HydrophobicContact CG-CG 3.95Å; F137-W144 HydrophobicContact CE1-CE3 4.03Å; F137-W144 HydrophobicContact CE1-CZ3 4.32Å; F137-W144 HydrophobicContact CE2-CB 4.18Å; F137-W144 HydrophobicContact CZ-CB 4.03Å; F137-W144 AromaticContact CZ-CD2 3.91Å; F137-W144 HydrophobicContact CZ-CD2 3.91Å; F137-W144 AromaticContact CZ-CE3 3.49Å; F137-W144 HydrophobicContact CZ-CE3 3.49Å; F137-W144 VanDerWaalsContact CZ-CE3 3.49Å; F137-W144 HydrophobicContact CZ-CG 4.18Å; F137-W144 HydrophobicContact CZ-CZ3 4.23Å; G140-W144 PolarHBondContact O-N 3.12Å; K141-W144 WeakPolarHBondContact O-CB 3.38Å; K141-W144 PolarHBondContact O-N 3.05Å; V142-W144 VanDerWaalsContact C-N 3.29Å; V142-W144 PolarHBondContact O-N 3.4Å; W144-I146 PolarHBondContact O-N 3.5Å; W144-L147 PolarHBondContact O-N 3.08Å; W144-F148 AromaticContact CD1-CD2 3.85Å; W144-F148 AromaticContact CD2-CD2 3.57Å; W144-F148 HydrophobicContact CD2-CD2 3.57Å; W144-F148 AromaticContact CD2-CE2 3.35Å; W144-F148 HydrophobicContact CD2-CE2 3.35Å; W144-F148 AromaticContact CE2-CD2 3.41Å; W144-F148 VanDerWaalsContact CE2-CD2 3.41Å; W144-F148 AromaticContact CE2-CE2 3.3Å; W144-F148 HydrophobicContact CE3-CD2 4.11Å; W144-F148 AromaticContact CE3-CE2 3.41Å; W144-F148 HydrophobicContact CE3-CE2 3.41Å; W144-F148 VanDerWaalsContact CE3-CE2 3.41Å; W144-F148 HydrophobicContact CE3-CZ 4.39Å; W144-F148 AromaticContact CG-CD2 3.86Å; W144-F148 HydrophobicContact CG-CD2 3.86Å; W144-F148 HydrophobicContact CG-CE2 4.1Å; W144-F148 HydrophobicContact CH2-CD2 4.38Å; W144-F148 AromaticContact CH2-CE2 3.46Å; W144-F148 HydrophobicContact CH2-CE2 3.46Å; W144-F148 VanDerWaalsContact CH2-CE2 3.46Å; W144-F148 AromaticContact CH2-CZ 3.82Å; W144-F148 HydrophobicContact CH2-CZ 3.82Å; W144-F148 AromaticContact CZ2-CD2 3.87Å; W144-F148 HydrophobicContact CZ2-CD2 3.87Å; W144-F148 AromaticContact CZ2-CE2 3.37Å; W144-F148 HydrophobicContact CZ2-CE2 3.37Å; W144-F148 AromaticContact CZ2-CZ 3.97Å; W144-F148 HydrophobicContact CZ2-CZ 3.97Å; W144-F148 HydrophobicContact CZ3-CD2 4.49Å; W144-F148 AromaticContact CZ3-CE2 3.48Å; W144-F148 HydrophobicContact CZ3-CE2 3.48Å; W144-F148 VanDerWaalsContact CZ3-CE2 3.48Å; W144-F148 HydrophobicContact CZ3-CZ 4.04Å; W144-F148 AromaticContact NE1-CD2 3.56Å; W144-F148 AromaticContact NE1-CE2 3.96Å; W144-F148 VanDerWaalsContact O-CD2 3.28Å; W144-F148 WeakPolarHBondContact O-CD2 3.48Å; W144-F148 PolarHBondContact O-N 2.85Å
145	Y	93.5	Very high	88.9	Confident	2 Å²	2	52.7 Å²	52.7	1%	0.008	28%	0.275	C	S	.	.	H	α-helix	trans	-64.3	-39.8	-179.9	-71.5	-63.5	0	0	0	112.7	Y66 L67 A71 L73 I81 I131 K141 V142 Y149	Y66-Y145 HydrophobicContact CE1-CE1 4Å; L67-Y145 HydrophobicContact CD2-CD1 4Å; L67-Y145 HydrophobicContact CD2-CD2 4.07Å; L67-Y145 HydrophobicContact CD2-CE1 4.25Å; L67-Y145 HydrophobicContact CD2-CE2 4.3Å; L67-Y145 HydrophobicContact CD2-CG 3.92Å; A71-Y145 HydrophobicContact CB-CE2 3.88Å; A71-Y145 WeakPolarHBondContact CB-OH 3.33Å; L73-Y145 HydrophobicContact CD1-CD2 3.73Å; L73-Y145 HydrophobicContact CD1-CE2 3.94Å; I81-Y145 HydrophobicContact CD1-CD2 4.39Å; I81-Y145 HydrophobicContact CD1-CG 4.43Å; I131-Y145 VanDerWaalsContact O-CE1 3.28Å; I131-Y145 WeakPolarHBondContact O-CE1 3.41Å; K141-Y145 HydrophobicContact CB-CE2 4.44Å; K141-Y145 WeakPolarHBondContact O-CD2 3.2Å; K141-Y145 PolarHBondContact O-N 3.35Å; V142-Y145 PolarHBondContact O-N 3.46Å; Y145-Y149 WeakPolarHBondContact O-CB 3.5Å; Y145-Y149 PolarHBondContact O-N 2.83Å
146	I	93.6	Very high	89.1	Confident	41 Å²	41	52.7 Å²	52.7	21%	0.21	28%	0.275	C	S	.	.	H	α-helix	trans	-60.9	-48.8	175	-67.6	173.1	0	0	0	110.5	I80 I81 I84 V142 I143 W144 Y149 C150	I80-I146 HydrophobicContact CG2-CD1 4.15Å; I81-I146 HydrophobicContact CB-CG1 4.47Å; I81-I146 HydrophobicContact CG1-CD1 4.45Å; I81-I146 HydrophobicContact CG1-CG1 3.76Å; I84-I146 HydrophobicContact CD1-CD1 4.3Å; I84-I146 HydrophobicContact CG2-CG2 4.19Å; V142-I146 HydrophobicContact CG1-CD1 3.92Å; V142-I146 WeakPolarHBondContact O-CG1 3.36Å; V142-I146 PolarHBondContact O-N 3.45Å; I143-I146 PolarHBondContact O-N 3.47Å; W144-I146 PolarHBondContact O-N 3.5Å; I146-Y149 PolarHBondContact O-N 3.22Å; I146-C150 WeakPolarHBondContact O-CB 3.35Å; I146-C150 PolarHBondContact O-N 2.91Å; I146-C150 PolarHBondContact O-SG 3.35Å
147	L	94.1	Very high	89.5	Confident	89 Å²	89	47.4 Å²	47.4	47%	0.466	24%	0.241	S	C	.	.	H	α-helix	trans	-62.9	-53	-176.9	-178.2	144.6	0	0	0	111.3	I143 W144 Y149 C150 V151	I143-L147 VanDerWaalsContact O-CB 3.24Å; I143-L147 WeakPolarHBondContact O-CB 3.15Å; I143-L147 PolarHBondContact O-N 3.44Å; W144-L147 PolarHBondContact O-N 3.08Å; L147-Y149 VanDerWaalsContact C-N 3.32Å; L147-Y149 PolarHBondContact O-N 2.96Å; L147-C150 PolarHBondContact O-N 2.95Å; L147-V151 HydrophobicContact CD2-CG2 4.31Å; L147-V151 WeakPolarHBondContact O-CB 3.31Å; L147-V151 WeakPolarHBondContact O-CG2 3.24Å; L147-V151 PolarHBondContact O-N 3.41Å
148	F	94.1	Very high	89.5	Confident	33 Å²	33	43.9 Å²	43.9	15%	0.145	23%	0.227	C	C	.	.	H	α-helix	trans	-68.5	-32.9	-178.5	-76.6	-69.3	0	0	0	112.6	L130 I131 W144 F152	L130-F148 HydrophobicContact CB-CD1 3.79Å; L130-F148 HydrophobicContact CB-CD2 4.36Å; L130-F148 HydrophobicContact CB-CE1 4.07Å; L130-F148 HydrophobicContact CB-CG 3.95Å; L130-F148 HydrophobicContact CB-CZ 4.47Å; L130-F148 HydrophobicContact CD1-CD1 3.77Å; L130-F148 HydrophobicContact CD1-CE1 3.24Å; L130-F148 HydrophobicContact CD1-CZ 3.72Å; L130-F148 HydrophobicContact CG-CD1 4.43Å; L130-F148 HydrophobicContact CG-CE1 4.26Å; I131-F148 HydrophobicContact CG1-CB 4.05Å; W144-F148 AromaticContact CD1-CD2 3.85Å; W144-F148 AromaticContact CD2-CD2 3.57Å; W144-F148 HydrophobicContact CD2-CD2 3.57Å; W144-F148 AromaticContact CD2-CE2 3.35Å; W144-F148 HydrophobicContact CD2-CE2 3.35Å; W144-F148 AromaticContact CE2-CD2 3.41Å; W144-F148 VanDerWaalsContact CE2-CD2 3.41Å; W144-F148 AromaticContact CE2-CE2 3.3Å; W144-F148 HydrophobicContact CE3-CD2 4.11Å; W144-F148 AromaticContact CE3-CE2 3.41Å; W144-F148 HydrophobicContact CE3-CE2 3.41Å; W144-F148 VanDerWaalsContact CE3-CE2 3.41Å; W144-F148 HydrophobicContact CE3-CZ 4.39Å; W144-F148 AromaticContact CG-CD2 3.86Å; W144-F148 HydrophobicContact CG-CD2 3.86Å; W144-F148 HydrophobicContact CG-CE2 4.1Å; W144-F148 HydrophobicContact CH2-CD2 4.38Å; W144-F148 AromaticContact CH2-CE2 3.46Å; W144-F148 HydrophobicContact CH2-CE2 3.46Å; W144-F148 VanDerWaalsContact CH2-CE2 3.46Å; W144-F148 AromaticContact CH2-CZ 3.82Å; W144-F148 HydrophobicContact CH2-CZ 3.82Å; W144-F148 AromaticContact CZ2-CD2 3.87Å; W144-F148 HydrophobicContact CZ2-CD2 3.87Å; W144-F148 AromaticContact CZ2-CE2 3.37Å; W144-F148 HydrophobicContact CZ2-CE2 3.37Å; W144-F148 AromaticContact CZ2-CZ 3.97Å; W144-F148 HydrophobicContact CZ2-CZ 3.97Å; W144-F148 HydrophobicContact CZ3-CD2 4.49Å; W144-F148 AromaticContact CZ3-CE2 3.48Å; W144-F148 HydrophobicContact CZ3-CE2 3.48Å; W144-F148 VanDerWaalsContact CZ3-CE2 3.48Å; W144-F148 HydrophobicContact CZ3-CZ 4.04Å; W144-F148 AromaticContact NE1-CD2 3.56Å; W144-F148 AromaticContact NE1-CE2 3.96Å; W144-F148 VanDerWaalsContact O-CD2 3.28Å; W144-F148 WeakPolarHBondContact O-CD2 3.48Å; W144-F148 PolarHBondContact O-N 2.85Å; F148-F152 WeakPolarHBondContact O-CB 3.39Å; F148-F152 PolarHBondContact O-N 2.81Å
149	Y	93.6	Very high	90	Very high	3 Å²	3	37.6 Å²	37.6	1%	0.012	20%	0.197	C	C	.	.	H	α-helix	trans	-67.4	-45	174.9	-168.3	-160.6	0	0	0	111.5	L59 L63 I81 R86 I131 Y145 I146 L147 F152 Q153	L59-Y149 HydrophobicContact CD1-CE2 3.99Å; L63-Y149 HydrophobicContact CD2-CD1 4.37Å; L63-Y149 HydrophobicContact CD2-CE1 3.96Å; L63-Y149 HydrophobicContact CD2-CE2 4.5Å; I81-Y149 HydrophobicContact CG2-CD1 4.17Å; R86-Y149 PolarHBondContact NE-OH 2.93Å; I131-Y149 HydrophobicContact CD1-CD2 4.16Å; Y145-Y149 WeakPolarHBondContact O-CB 3.5Å; Y145-Y149 PolarHBondContact O-N 2.83Å; I146-Y149 PolarHBondContact O-N 3.22Å; L147-Y149 VanDerWaalsContact C-N 3.32Å; L147-Y149 PolarHBondContact O-N 2.96Å; Y149-F152 PolarHBondContact O-N 3.18Å; Y149-Q153 HydrophobicContact CD2-CG 3.86Å; Y149-Q153 HydrophobicContact CE2-CG 3.71Å; Y149-Q153 WeakPolarHBondContact O-CG 3.39Å; Y149-Q153 PolarHBondContact O-N 2.95Å; Y149-Q153 PolarHBondContact OH-NE2 3.44Å
150	C	93.8	Very high	90.4	Very high	19 Å²	19	29.8 Å²	29.8	13%	0.128	16%	0.161	C	C	.	.	H	α-helix	trans	-66.4	-40.3	177.2	-64.5	0	0	0	0	112.5	W88 I146 L147 Q153 T154	W88-C150 HydrophobicContact CG-CB 4.11Å; W88-C150 PolarHBondContact NE1-O 3.34Å; I146-C150 WeakPolarHBondContact O-CB 3.35Å; I146-C150 PolarHBondContact O-N 2.91Å; I146-C150 PolarHBondContact O-SG 3.35Å; L147-C150 PolarHBondContact O-N 2.95Å; C150-Q153 PolarHBondContact O-N 2.86Å; C150-T154 PolarHBondContact O-N 2.78Å; C150-T154 PolarHBondContact O-OG1 2.83Å
151	V	93.6	Very high	90.3	Very high	58 Å²	58	29.7 Å²	29.7	35%	0.352	16%	0.156	S	C	.	.	H	α-helix	trans	-62.2	-47.4	175.3	169.2	0	0	0	0	110.2	L147 Q153 T154 L155	L147-V151 HydrophobicContact CD2-CG2 4.31Å; L147-V151 WeakPolarHBondContact O-CB 3.31Å; L147-V151 WeakPolarHBondContact O-CG2 3.24Å; L147-V151 PolarHBondContact O-N 3.41Å; V151-Q153 PolarHBondContact O-N 3.32Å; V151-T154 PolarHBondContact O-N 2.94Å; V151-L155 HydrophobicContact CG1-CD1 3.63Å; V151-L155 HydrophobicContact CG1-CG 4.34Å; V151-L155 WeakPolarHBondContact O-CB 3.21Å; V151-L155 VanDerWaalsContact O-CG 3.24Å; V151-L155 WeakPolarHBondContact O-CG 3.41Å; V151-L155 PolarHBondContact O-N 3.27Å
152	F	93.9	Very high	89.9	Confident	2 Å²	2	29.4 Å²	29.4	1%	0.009	16%	0.155	C	C	.	.	H	α-helix	trans	-57.2	-49.6	176.1	172.4	-104.5	0	0	0	111.4	T55 L59 A124 S127 Y128 I131 F148 Y149 T154 L155 Q156	T55-F152 HydrophobicContact CG2-CE2 4.43Å; T55-F152 HydrophobicContact CG2-CZ 3.96Å; L59-F152 HydrophobicContact CD1-CD1 3.95Å; L59-F152 HydrophobicContact CD1-CE1 3.49Å; L59-F152 VanDerWaalsContact CD1-CE1 3.49Å; L59-F152 HydrophobicContact CD1-CZ 4.43Å; A124-F152 WeakPolarHBondContact O-CD2 3.49Å; S127-F152 WeakPolarHBondContact OG-CA 2.93Å; Y128-F152 HydrophobicContact CD2-CD2 4.16Å; Y128-F152 HydrophobicContact CD2-CE1 4.18Å; Y128-F152 AromaticContact CD2-CE2 3.71Å; Y128-F152 HydrophobicContact CD2-CE2 3.71Å; Y128-F152 AromaticContact CD2-CZ 3.73Å; Y128-F152 HydrophobicContact CD2-CZ 3.73Å; Y128-F152 HydrophobicContact CE2-CZ 4.44Å; Y128-F152 HydrophobicContact CG-CD2 4.43Å; Y128-F152 HydrophobicContact CG-CE2 4.08Å; I131-F152 HydrophobicContact CD1-CB 3.73Å; I131-F152 HydrophobicContact CD1-CD1 4.1Å; I131-F152 HydrophobicContact CD1-CG 3.95Å; F148-F152 WeakPolarHBondContact O-CB 3.39Å; F148-F152 PolarHBondContact O-N 2.81Å; Y149-F152 PolarHBondContact O-N 3.18Å; F152-T154 VanDerWaalsContact C-N 3.34Å; F152-T154 PolarHBondContact O-N 3.25Å; F152-L155 PolarHBondContact O-N 3.07Å; F152-Q156 HydrophobicContact CE1-CB 4.47Å; F152-Q156 HydrophobicContact CZ-CB 4.28Å; F152-Q156 HydrophobicContact CZ-CG 4.29Å; F152-Q156 WeakPolarHBondContact O-CB 3.39Å; F152-Q156 PolarHBondContact O-N 3.12Å
153	Q	91.9	Very high	89.5	Confident	10 Å²	10	28.2 Å²	28.2	5%	0.047	15%	0.147	C	C	.	.	H	α-helix	trans	-60.2	-43.1	179.5	-66.6	-72.9	35	0	0	112.1	D89 Y149 C150 V151 L155 Q156 T157	D89-Q153 HydrophobicContact CB-CB 4.08Å; D89-Q153 HydrophobicContact CB-CG 4.04Å; Y149-Q153 HydrophobicContact CD2-CG 3.86Å; Y149-Q153 HydrophobicContact CE2-CG 3.71Å; Y149-Q153 WeakPolarHBondContact O-CG 3.39Å; Y149-Q153 PolarHBondContact O-N 2.95Å; Y149-Q153 PolarHBondContact OH-NE2 3.44Å; C150-Q153 PolarHBondContact O-N 2.86Å; V151-Q153 PolarHBondContact O-N 3.32Å; Q153-L155 PolarHBondContact O-N 3.07Å; Q153-Q156 PolarHBondContact O-N 3.05Å; Q153-T157 WeakPolarHBondContact O-CB 3.3Å; Q153-T157 PolarHBondContact O-N 3.44Å; Q153-T157 PolarHBondContact O-OG1 3.25Å; Q153-T157 VanDerWaalsContact O-OG1 3.06Å
154	T	90.4	Very high	88.8	Confident	44 Å²	44	24.3 Å²	24.3	27%	0.27	13%	0.131	S	C	.	.	H	α-helix	trans	-60.5	-46.9	177	-49.8	0	0	0	0	111.7	W88 T92 C150 V151 F152 T157 C158	W88-T154 PolarHBondContact NE1-OG1 3.15Å; T92-T154 HydrophobicContact CG2-CG2 4.36Å; C150-T154 PolarHBondContact O-N 2.78Å; C150-T154 PolarHBondContact O-OG1 2.83Å; V151-T154 PolarHBondContact O-N 2.94Å; F152-T154 VanDerWaalsContact C-N 3.34Å; F152-T154 PolarHBondContact O-N 3.25Å; T154-T157 PolarHBondContact O-N 3.17Å; T154-C158 PolarHBondContact O-N 3.02Å; T154-C158 PolarHBondContact O-SG 3.46Å
155	L	90.5	Very high	88	Confident	34 Å²	34	23 Å²	23	18%	0.178	13%	0.132	C	C	.	.	H	α-helix	trans	-69.2	-36.5	-179.1	-65.4	170.4	0	0	0	111.7	S120 F123 A124 V151 F152 Q153 C158 F159	S120-L155 WeakPolarHBondContact OG-CA 3.14Å; S120-L155 WeakPolarHBondContact OG-CB 3.42Å; S120-L155 PolarHBondContact OG-O 3.26Å; F123-L155 VanDerWaalsContact C-CD1 3.48Å; F123-L155 HydrophobicContact CB-CD1 3.67Å; F123-L155 HydrophobicContact CB-CD2 4.44Å; A124-L155 HydrophobicContact CB-CB 3.82Å; V151-L155 HydrophobicContact CG1-CD1 3.63Å; V151-L155 HydrophobicContact CG1-CG 4.34Å; V151-L155 WeakPolarHBondContact O-CB 3.21Å; V151-L155 VanDerWaalsContact O-CG 3.24Å; V151-L155 WeakPolarHBondContact O-CG 3.41Å; V151-L155 PolarHBondContact O-N 3.27Å; F152-L155 PolarHBondContact O-N 3.07Å; Q153-L155 PolarHBondContact O-N 3.07Å; L155-C158 WeakPolarHBondContact O-CB 3.33Å; L155-C158 PolarHBondContact O-N 3.2Å; L155-F159 PolarHBondContact O-N 3.47Å; L155-F159 VanDerWaalsContact O-N 3.17Å
156	Q	88.9	Confident	87.2	Confident	2 Å²	2	23 Å²	23	1%	0.009	13%	0.133	C	C	.	.	H	α-helix	trans	-62.6	-46.5	173.6	-171.7	62.4	36.9	0	0	111.1	Y52 F152 Q153 C158 F159 H160 Y252	Y52-Q156 HydrophobicContact CD2-CG 3.95Å; F152-Q156 HydrophobicContact CE1-CB 4.47Å; F152-Q156 HydrophobicContact CZ-CB 4.28Å; F152-Q156 HydrophobicContact CZ-CG 4.29Å; F152-Q156 WeakPolarHBondContact O-CB 3.39Å; F152-Q156 PolarHBondContact O-N 3.12Å; Q153-Q156 PolarHBondContact O-N 3.05Å; Q156-C158 VanDerWaalsContact C-N 3.34Å; Q156-C158 PolarHBondContact O-N 3.42Å; Q156-F159 WeakPolarHBondContact O-CB 3.27Å; Q156-F159 PolarHBondContact O-N 3.38Å; Q156-F159 VanDerWaalsContact O-N 3.09Å; Q156-H160 WeakPolarHBondContact O-CB 2.94Å; Q156-H160 PolarHBondContact O-N 3.37Å; Q156-Y252 PolarHBondContact NE2-OH 3.31Å; Q156-Y252 PolarHBondContact OE1-OH 2.96Å
157	T	87.4	Confident	86.3	Confident	1 Å²	1	22 Å²	22	1%	0.006	13%	0.128	C	C	.	.	H	α-helix	trans	-59.1	-45	173.9	-64.7	0	0	0	0	111	T92 D93 V96 Q153 T154 F159 H160 V161	T92-T157 PolarHBondContact OG1-OG1 3.22Å; T92-T157 VanDerWaalsContact OG1-OG1 3.1Å; D93-T157 HydrophobicContact CB-CG2 4.43Å; D93-T157 WeakPolarHBondContact OD1-CG2 3.33Å; D93-T157 PolarHBondContact OD1-OG1 3.47Å; V96-T157 HydrophobicContact CB-CG2 3.68Å; V96-T157 HydrophobicContact CG1-CG2 4.13Å; V96-T157 HydrophobicContact CG2-CG2 3.66Å; Q153-T157 WeakPolarHBondContact O-CB 3.3Å; Q153-T157 PolarHBondContact O-N 3.44Å; Q153-T157 PolarHBondContact O-OG1 3.25Å; Q153-T157 VanDerWaalsContact O-OG1 3.06Å; T154-T157 PolarHBondContact O-N 3.17Å; T157-F159 PolarHBondContact O-N 3.03Å; T157-F159 VanDerWaalsContact O-N 3.12Å; T157-H160 PolarHBondContact O-N 3.46Å; T157-V161 HydrophobicContact CG2-CG2 3.66Å; T157-V161 WeakPolarHBondContact O-CB 3.11Å; T157-V161 PolarHBondContact O-N 3.29Å
158	C	84.7	Confident	85.2	Confident	10 Å²	10	22 Å²	22	7%	0.068	13%	0.127	C	C	.	.	H	α-helix	trans	-59.1	-21.1	176	-74	0	0	0	0	113.8	Y115 T154 L155 Q156 P162	Y115-C158 HydrophobicContact CD1-CB 4.26Å; Y115-C158 HydrophobicContact CG-CB 4.43Å; T154-C158 PolarHBondContact O-N 3.02Å; T154-C158 PolarHBondContact O-SG 3.46Å; L155-C158 WeakPolarHBondContact O-CB 3.33Å; L155-C158 PolarHBondContact O-N 3.2Å; Q156-C158 VanDerWaalsContact C-N 3.34Å; Q156-C158 PolarHBondContact O-N 3.42Å; C158-P162 WeakPolarHBondContact O-CD 3.37Å; C158-P162 VanDerWaalsContact O-CG 3.31Å; C158-P162 WeakPolarHBondContact O-CG 3.44Å
159	F	84.8	Confident	84.2	Confident	1 Å²	1	22.1 Å²	22.1	0%	0.004	13%	0.128	C	C	.	.	H	α-helix	trans	-91.4	-51.3	172.9	179.5	-92	0	0	0	111.9	G48 P51 A116 L155 Q156 T157 Y163 Y252 A256 L259	G48-F159 VanDerWaalsContact O-CE1 3.31Å; G48-F159 WeakPolarHBondContact O-CE1 3.37Å; P51-F159 HydrophobicContact CG-CE1 4.4Å; A116-F159 HydrophobicContact CB-CD2 4.09Å; L155-F159 PolarHBondContact O-N 3.47Å; L155-F159 VanDerWaalsContact O-N 3.17Å; Q156-F159 WeakPolarHBondContact O-CB 3.27Å; Q156-F159 PolarHBondContact O-N 3.38Å; Q156-F159 VanDerWaalsContact O-N 3.09Å; T157-F159 PolarHBondContact O-N 3.03Å; T157-F159 VanDerWaalsContact O-N 3.12Å; F159-Y163 WeakPolarHBondContact O-CB 2.97Å; F159-Y163 PolarHBondContact O-N 3.48Å; F159-Y252 WeakPolarHBondContact CB-OH 3.44Å; F159-Y252 WeakPolarHBondContact CD1-OH 3.27Å; F159-Y252 HydrophobicContact CD2-CE1 4.4Å; F159-Y252 HydrophobicContact CE2-CE1 4.42Å; F159-Y252 VanDerWaalsContact CG-OH 3.26Å; F159-Y252 WeakPolarHBondContact CG-OH 3.16Å; F159-A256 HydrophobicContact CE2-CB 4.13Å; F159-L259 HydrophobicContact CE2-CD2 4.44Å; F159-L259 HydrophobicContact CZ-CD2 4.16Å
160	H	83.7	Confident	83.2	Confident	26 Å²	26	22.9 Å²	22.9	12%	0.12	13%	0.132	C	C	.	.	H	α-helix	trans	-69.6	-41.1	-171.4	177	-102.7	0	0	0	113.3	Y52 Q156 T157 Y163 S164	Y52-H160 AromaticContact CD1-CD2 3.68Å; Y52-H160 AromaticContact CD1-NE2 3.67Å; Y52-H160 HydrophobicContact CD2-CB 3.98Å; Y52-H160 AromaticContact CD2-CD2 3.92Å; Y52-H160 AromaticContact CD2-CG 3.78Å; Y52-H160 AromaticContact CE1-NE2 3.93Å; Y52-H160 HydrophobicContact CG-CB 4.32Å; Y52-H160 AromaticContact CG-CD2 3.48Å; Y52-H160 VanDerWaalsContact CG-CD2 3.48Å; Y52-H160 AromaticContact CG-CG 3.85Å; Y52-H160 AromaticContact CG-NE2 3.98Å; Q156-H160 WeakPolarHBondContact O-CB 2.94Å; Q156-H160 PolarHBondContact O-N 3.37Å; T157-H160 PolarHBondContact O-N 3.46Å; H160-Y163 WeakPolarHBondContact O-CB 3.46Å; H160-Y163 PolarHBondContact O-N 2.78Å; H160-S164 WeakPolarHBondContact O-CB 3.38Å; H160-S164 PolarHBondContact O-N 3.42Å; H160-S164 PolarHBondContact O-OG 3.13Å
161	V	81.6	Confident	82.2	Confident	23 Å²	23	22.6 Å²	22.6	14%	0.139	13%	0.13	C	C	.	.	H	α-helix	trans	-64	-52.8	-177.3	172.1	0	0	0	0	111.5	V96 T157 Y163 S164 A165	V96-V161 HydrophobicContact CG1-CB 4.24Å; V96-V161 HydrophobicContact CG1-CG1 4.48Å; T157-V161 HydrophobicContact CG2-CG2 3.66Å; T157-V161 WeakPolarHBondContact O-CB 3.11Å; T157-V161 PolarHBondContact O-N 3.29Å; V161-Y163 VanDerWaalsContact C-N 3.29Å; V161-Y163 PolarHBondContact O-N 3.44Å; V161-S164 PolarHBondContact O-N 3.25Å; V161-S164 PolarHBondContact O-OG 3Å; V161-A165 PolarHBondContact O-N 3.38Å; V161-A165 VanDerWaalsContact O-N 3.17Å
162	P	78.3	Confident	81	Confident	6 Å²	6	24 Å²	24	4%	0.039	14%	0.142	C	C	.	.	H	α-helix	trans	-58.5	-40	173.3	-24.2	34	0	0	0	113.1	V100 M111 C158 S164 A165 L166	V100-P162 HydrophobicContact CG1-CG 4.48Å; V100-P162 HydrophobicContact CG2-CG 3.85Å; M111-P162 HydrophobicContact CB-CB 4.26Å; C158-P162 WeakPolarHBondContact O-CD 3.37Å; C158-P162 VanDerWaalsContact O-CG 3.31Å; C158-P162 WeakPolarHBondContact O-CG 3.44Å; P162-S164 PolarHBondContact O-N 3.03Å; P162-A165 PolarHBondContact O-N 3.05Å; P162-L166 WeakPolarHBondContact O-CB 3.43Å; P162-L166 PolarHBondContact O-N 3.1Å
163	Y	82.4	Confident	79.9	Confident	5 Å²	5	29 Å²	29	2%	0.02	17%	0.165	C	C	.	.	H	α-helix	trans	-60.3	-44.3	178.3	166.6	-103.7	0	0	0	112.9	Y45 A46 G49 F159 H160 V161 L166 R184 L259	Y45-Y163 HydrophobicContact CD2-CD2 4.5Å; Y45-Y163 AromaticContact CD2-CE2 3.79Å; Y45-Y163 HydrophobicContact CD2-CE2 3.79Å; Y45-Y163 AromaticContact CE2-CD2 3.93Å; Y45-Y163 HydrophobicContact CE2-CD2 3.93Å; Y45-Y163 AromaticContact CE2-CE2 3.39Å; Y45-Y163 HydrophobicContact CE2-CE2 3.39Å; Y45-Y163 AromaticContact CE2-CZ 3.91Å; Y45-Y163 AromaticContact CZ-CE2 3.85Å; Y45-Y163 AromaticContact CZ-CZ 3.86Å; Y45-Y163 WeakPolarHBondContact O-CE2 3.46Å; Y45-Y163 PolarHBondContact O-OH 3.29Å; Y45-Y163 PolarHBondContact OH-O 2.87Å; Y45-Y163 VanDerWaalsContact OH-O 3.08Å; A46-Y163 PolarHBondContact O-OH 3.23Å; G49-Y163 WeakPolarHBondContact CA-OH 3.41Å; G49-Y163 PolarHBondContact N-OH 2.81Å; F159-Y163 WeakPolarHBondContact O-CB 2.97Å; F159-Y163 PolarHBondContact O-N 3.48Å; H160-Y163 WeakPolarHBondContact O-CB 3.46Å; H160-Y163 PolarHBondContact O-N 2.78Å; V161-Y163 VanDerWaalsContact C-N 3.29Å; V161-Y163 PolarHBondContact O-N 3.44Å; Y163-L166 VanDerWaalsContact O-CB 3.24Å; Y163-L166 WeakPolarHBondContact O-CB 3.47Å; Y163-L166 PolarHBondContact O-N 3.31Å; Y163-R184 HydrophobicContact CE1-CG 4.19Å; Y163-R184 WeakPolarHBondContact OH-CD 3.39Å; Y163-R184 VanDerWaalsContact OH-CG 3.28Å; Y163-R184 WeakPolarHBondContact OH-CG 3.21Å; Y163-L259 HydrophobicContact CD2-CD1 4.06Å; Y163-L259 HydrophobicContact CD2-CD2 3.73Å; Y163-L259 HydrophobicContact CE2-CD1 3.97Å; Y163-L259 HydrophobicContact CE2-CD2 4.33Å
164	S	78.1	Confident	78.8	Confident	41 Å²	41	34.8 Å²	34.8	29%	0.287	19%	0.192	S	C	.	.	H	α-helix	trans	-65	-41.1	178	68.4	0	0	0	0	111.5	H160 V161 P162 L166 T167	H160-S164 WeakPolarHBondContact O-CB 3.38Å; H160-S164 PolarHBondContact O-N 3.42Å; H160-S164 PolarHBondContact O-OG 3.13Å; V161-S164 PolarHBondContact O-N 3.25Å; V161-S164 PolarHBondContact O-OG 3Å; P162-S164 PolarHBondContact O-N 3.03Å; S164-L166 VanDerWaalsContact C-N 3.29Å; S164-L166 PolarHBondContact O-N 2.88Å; S164-T167 PolarHBondContact O-OG1 2.96Å
165	A	75.2	Confident	77.9	Confident	32 Å²	32	40 Å²	40	26%	0.264	21%	0.212	S	C	.	.	H	α-helix	trans	-70.8	-23.1	177.3	0	0	0	0	0	113.3	M111 V161 P162 T167 M168 F169	M111-A165 HydrophobicContact CE-CB 3.96Å; V161-A165 PolarHBondContact O-N 3.38Å; V161-A165 VanDerWaalsContact O-N 3.17Å; P162-A165 PolarHBondContact O-N 3.05Å; A165-T167 PolarHBondContact O-N 2.95Å; A165-M168 WeakPolarHBondContact O-CB 3.17Å; A165-M168 PolarHBondContact O-N 3.24Å; A165-M168 VanDerWaalsContact O-N 3.08Å; A165-F169 WeakPolarHBondContact O-CD2 3.32Å
166	L	77.1	Confident	77.3	Confident	3 Å²	3	39.5 Å²	39.5	2%	0.016	21%	0.208	C	C	.	.	H	α-helix	trans	-58.4	-29.5	-179.3	-169	68.1	0	0	0	112.5	Y45 M111 M112 P162 Y163 S164 M168 F169 I170 L259 V263 E265	Y45-L166 HydrophobicContact CD2-CD2 4.14Å; Y45-L166 HydrophobicContact CE2-CB 4.1Å; Y45-L166 HydrophobicContact CE2-CD2 4.15Å; Y45-L166 HydrophobicContact CE2-CG 4.4Å; M111-L166 HydrophobicContact CB-CD1 4.29Å; M112-L166 HydrophobicContact CE-CD2 4.39Å; M112-L166 HydrophobicContact CG-CD1 4.21Å; M112-L166 HydrophobicContact SD-CD2 4.44Å; P162-L166 WeakPolarHBondContact O-CB 3.43Å; P162-L166 PolarHBondContact O-N 3.1Å; Y163-L166 VanDerWaalsContact O-CB 3.24Å; Y163-L166 WeakPolarHBondContact O-CB 3.47Å; Y163-L166 PolarHBondContact O-N 3.31Å; S164-L166 VanDerWaalsContact C-N 3.29Å; S164-L166 PolarHBondContact O-N 2.88Å; L166-M168 PolarHBondContact O-N 3.46Å; L166-M168 VanDerWaalsContact O-N 3.1Å; L166-F169 PolarHBondContact O-N 3.31Å; L166-I170 HydrophobicContact CD2-CD1 4.12Å; L166-I170 HydrophobicContact CG-CD1 3.8Å; L166-I170 HydrophobicContact CG-CG1 4Å; L166-I170 VanDerWaalsContact O-CG1 3.26Å; L166-I170 WeakPolarHBondContact O-CG1 3.16Å; L166-I170 PolarHBondContact O-N 3.1Å; L166-I170 VanDerWaalsContact O-N 3.13Å; L166-L259 HydrophobicContact CD2-CD1 4.24Å; L166-V263 HydrophobicContact CD2-CG1 3.93Å; L166-E265 HydrophobicContact CD1-CG 3.45Å; L166-E265 VanDerWaalsContact CD1-CG 3.45Å; L166-E265 VanDerWaalsContact CD1-OE1 3.3Å; L166-E265 WeakPolarHBondContact CD1-OE1 3.07Å
167	T	75.4	Confident	76.7	Confident	19 Å²	19	41.6 Å²	41.6	12%	0.117	22%	0.216	C	C	.	.	H	α-helix	trans	-47.5	-39.7	172.6	41.3	0	0	0	0	113	Y45 S164 A165 F169	Y45-T167 HydrophobicContact CE1-CG2 3.49Å; Y45-T167 VanDerWaalsContact CE1-CG2 3.49Å; Y45-T167 HydrophobicContact CE2-CG2 4.39Å; Y45-T167 WeakPolarHBondContact OH-CG2 3.09Å; S164-T167 PolarHBondContact O-OG1 2.96Å; A165-T167 PolarHBondContact O-N 2.95Å; T167-F169 VanDerWaalsContact C-N 3.32Å; T167-F169 PolarHBondContact O-N 3.25Å
168	M	70.6	Confident	76.2	Confident	90 Å²	90	46.2 Å²	46.2	44%	0.443	24%	0.241	S	C	.	.	H	α-helix	trans	-74.2	-23	-176.2	-61.4	-60.5	-73.9	0	0	113.1	A165 L166 R177	A165-M168 WeakPolarHBondContact O-CB 3.17Å; A165-M168 PolarHBondContact O-N 3.24Å; A165-M168 VanDerWaalsContact O-N 3.08Å; L166-M168 PolarHBondContact O-N 3.46Å; L166-M168 VanDerWaalsContact O-N 3.1Å; M168-R177 VanDerWaalsContact CE-NH1 3.28Å; M168-R177 PolarHBondContact O-NH2 3.04Å
169	F	71.8	Confident	76.1	Confident	35 Å²	35	47.5 Å²	47.5	15%	0.154	25%	0.25	C	C	.	.	H	α-helix	trans	-101.3	-6.7	-177.6	-63.5	-82	0	0	0	113.5	W105 M111 A165 L166 T167 H266 A268	W105-F169 HydrophobicContact CZ2-CD1 4.33Å; W105-F169 HydrophobicContact CZ2-CE1 4.48Å; M111-F169 HydrophobicContact CE-CD2 4.12Å; M111-F169 HydrophobicContact CE-CE2 3.3Å; M111-F169 HydrophobicContact CE-CZ 3.84Å; M111-F169 HydrophobicContact CG-CD2 4.01Å; M111-F169 HydrophobicContact CG-CE2 4.12Å; A165-F169 WeakPolarHBondContact O-CD2 3.32Å; L166-F169 PolarHBondContact O-N 3.31Å; T167-F169 VanDerWaalsContact C-N 3.32Å; T167-F169 PolarHBondContact O-N 3.25Å; F169-H266 PolarHBondContact O-N 3.44Å; F169-A268 HydrophobicContact CD1-CB 4Å; F169-A268 HydrophobicContact CE1-CB 4.25Å
170	I	72.4	Confident	76	Confident	19 Å²	19	47.7 Å²	47.7	10%	0.097	25%	0.251	C	S	.	.	H	α-helix	trans	-84	-35.5	178.1	-70.2	165.7	0	0	0	111.3	L37 Y45 L166 V263	L37-I170 HydrophobicContact CD1-CG2 3.59Å; L37-I170 HydrophobicContact CD2-CG2 3.26Å; L37-I170 HydrophobicContact CG-CG2 4.02Å; Y45-I170 HydrophobicContact CD2-CD1 3.28Å; Y45-I170 HydrophobicContact CE2-CD1 3.76Å; Y45-I170 HydrophobicContact CG-CD1 3.76Å; L166-I170 HydrophobicContact CD2-CD1 4.12Å; L166-I170 HydrophobicContact CG-CD1 3.8Å; L166-I170 HydrophobicContact CG-CG1 4Å; L166-I170 VanDerWaalsContact O-CG1 3.26Å; L166-I170 WeakPolarHBondContact O-CG1 3.16Å; L166-I170 PolarHBondContact O-N 3.1Å; L166-I170 VanDerWaalsContact O-N 3.13Å; I170-V263 HydrophobicContact CD1-CG1 3.68Å; I170-V263 HydrophobicContact CG1-CG1 3.73Å
171	T	74.5	Confident	75.9	Confident	14 Å²	14	48.4 Å²	48.4	9%	0.086	26%	0.257	C	S	.	.			trans	-149.5	148.9	178.5	-175.5	0	0	0	0	110.9	L37 E173 E176 R177	L37-T171 HydrophobicContact CD1-CG2 3.73Å; T171-E173 PolarHBondContact OG1-N 2.76Å; T171-E176 HydrophobicContact CG2-CB 3.74Å; T171-R177 HydrophobicContact CG2-CB 4.43Å; T171-R177 HydrophobicContact CG2-CG 3.49Å; T171-R177 VanDerWaalsContact CG2-CG 3.49Å; T171-R177 VanDerWaalsContact O-CZ 3.25Å; T171-R177 PolarHBondContact O-NE 2.94Å; T171-R177 PolarHBondContact O-NH2 2.79Å
172	S	67.7	Low	76	Confident	87 Å²	87	50 Å²	50	61%	0.608	27%	0.273	S	S	*	.	S	Bend	trans	-83.6	-23.3	171.1	52.9	0	0	0	0	112.6
173	E	71.3	Confident	76.4	Confident	107 Å²	107	54 Å²	54	50%	0.5	29%	0.288	S	S	.	.			trans	-80.1	121.3	-172	-172.5	64	-133.9	0	0	112	T171 K175 E176 R177	T171-E173 PolarHBondContact OG1-N 2.76Å; E173-K175 VanDerWaalsContact C-N 3.34Å; E173-K175 HydrophobicContact CG-CB 4.44Å; E173-K175 PolarHBondContact O-N 3.26Å; E173-E176 HydrophobicContact CB-CB 4.15Å; E173-E176 HydrophobicContact CB-CG 4.1Å; E173-E176 HydrophobicContact CG-CB 4.48Å; E173-E176 HydrophobicContact CG-CG 4.1Å; E173-E176 PolarHBondContact O-N 3.03Å; E173-E176 VanDerWaalsContact O-N 3.12Å; E173-R177 PolarHBondContact O-N 2.97Å; E173-R177 VanDerWaalsContact O-N 3.11Å
174	Q	67.4	Low	76.7	Confident	131 Å²	131	55.3 Å²	55.3	61%	0.612	29%	0.293	S	S	*	.	H	α-helix	trans	-54.8	-47.5	-177.4	-169.3	105.6	7.2	0	0	112.1	E176 R177 D178	Q174-E176 PolarHBondContact O-N 3.14Å; Q174-R177 WeakPolarHBondContact O-CB 3.28Å; Q174-R177 PolarHBondContact O-N 3.36Å; Q174-R177 VanDerWaalsContact O-N 3.09Å; Q174-D178 PolarHBondContact O-N 3.25Å
175	K	73	Confident	77	Confident	155 Å²	155	56.3 Å²	56.3	67%	0.674	29%	0.294	S	S	*	.	H	α-helix	trans	-59.8	-34.8	-178.9	-175	177.9	179.5	177.7	0	112.8	E173 S179	E173-K175 VanDerWaalsContact C-N 3.34Å; E173-K175 HydrophobicContact CG-CB 4.44Å; E173-K175 PolarHBondContact O-N 3.26Å; K175-S179 WeakPolarHBondContact O-CB 3.44Å; K175-S179 PolarHBondContact O-N 3.23Å
176	E	78	Confident	77.7	Confident	23 Å²	23	58.8 Å²	58.8	11%	0.107	31%	0.305	C	S	.	.	H	α-helix	trans	-76.8	-34	178.3	-68.9	-67	139.1	0	0	111.7	L37 K42 T171 E173 Q174 A180	L37-E176 HydrophobicContact CD1-CB 4.29Å; K42-E176 WeakPolarHBondContact CE-OE2 3.34Å; K42-E176 IonicContact NZ-OE1 3.05Å; K42-E176 IonicContact NZ-OE2 2.87Å; K42-E176 PolarHBondContact NZ-OE2 3.28Å; T171-E176 HydrophobicContact CG2-CB 3.74Å; E173-E176 HydrophobicContact CB-CB 4.15Å; E173-E176 HydrophobicContact CB-CG 4.1Å; E173-E176 HydrophobicContact CG-CB 4.48Å; E173-E176 HydrophobicContact CG-CG 4.1Å; E173-E176 PolarHBondContact O-N 3.03Å; E173-E176 VanDerWaalsContact O-N 3.12Å; Q174-E176 PolarHBondContact O-N 3.14Å; E176-A180 WeakPolarHBondContact O-CB 3.48Å; E176-A180 PolarHBondContact O-N 3.48Å
177	R	75.3	Confident	78.4	Confident	46 Å²	46	60.1 Å²	60.1	17%	0.174	31%	0.314	C	S	.	.	H	α-helix	trans	-64.3	-44.4	172.3	-64.9	-178	177.2	162.5	-3.7	112	M168 T171 E173 Q174 S179 A180 T181	M168-R177 VanDerWaalsContact CE-NH1 3.28Å; M168-R177 PolarHBondContact O-NH2 3.04Å; T171-R177 HydrophobicContact CG2-CB 4.43Å; T171-R177 HydrophobicContact CG2-CG 3.49Å; T171-R177 VanDerWaalsContact CG2-CG 3.49Å; T171-R177 VanDerWaalsContact O-CZ 3.25Å; T171-R177 PolarHBondContact O-NE 2.94Å; T171-R177 PolarHBondContact O-NH2 2.79Å; E173-R177 PolarHBondContact O-N 2.97Å; E173-R177 VanDerWaalsContact O-N 3.11Å; Q174-R177 WeakPolarHBondContact O-CB 3.28Å; Q174-R177 PolarHBondContact O-N 3.36Å; Q174-R177 VanDerWaalsContact O-N 3.09Å; R177-S179 VanDerWaalsContact C-N 3.33Å; R177-S179 PolarHBondContact O-N 3.26Å; R177-A180 PolarHBondContact O-N 3.35Å; R177-T181 WeakPolarHBondContact O-CB 3.4Å; R177-T181 PolarHBondContact O-N 3.29Å; R177-T181 PolarHBondContact O-OG1 2.98Å
178	D	76.9	Confident	79.1	Confident	98 Å²	98	59.8 Å²	59.8	52%	0.524	31%	0.311	S	S	.	.	H	α-helix	trans	-62.3	-44.3	178.2	-68.1	-17.5	0	0	0	110.6	Q174 T181 A182	Q174-D178 PolarHBondContact O-N 3.25Å; D178-T181 PolarHBondContact O-N 3.27Å; D178-A182 PolarHBondContact O-N 3.21Å
179	S	82.4	Confident	80	Confident	37 Å²	37	57.2 Å²	57.2	26%	0.259	30%	0.3	S	S	.	.	H	α-helix	trans	-59.9	-50.2	174.4	177.6	0	0	0	0	111.6	K42 K175 R177 T181 A182 Y183	K42-S179 PolarHBondContact NZ-OG 2.67Å; K175-S179 WeakPolarHBondContact O-CB 3.44Å; K175-S179 PolarHBondContact O-N 3.23Å; R177-S179 VanDerWaalsContact C-N 3.33Å; R177-S179 PolarHBondContact O-N 3.26Å; S179-T181 VanDerWaalsContact C-N 3.3Å; S179-T181 PolarHBondContact O-N 3.09Å; S179-A182 WeakPolarHBondContact O-CB 3.42Å; S179-A182 PolarHBondContact O-N 3.38Å; S179-Y183 WeakPolarHBondContact O-CD2 3.03Å; S179-Y183 PolarHBondContact O-N 3.11Å; S179-Y183 VanDerWaalsContact O-N 3.09Å
180	A	82.6	Confident	81	Confident	4 Å²	4	60.2 Å²	60.2	3%	0.033	32%	0.318	C	S	.	.	H	α-helix	trans	-60.7	-38.9	179	0	0	0	0	0	112.5	Y45 E176 R177 Y183 R184	Y45-A180 HydrophobicContact CD1-CB 4.23Å; E176-A180 WeakPolarHBondContact O-CB 3.48Å; E176-A180 PolarHBondContact O-N 3.48Å; R177-A180 PolarHBondContact O-N 3.35Å; A180-Y183 PolarHBondContact O-N 3.39Å; A180-R184 PolarHBondContact O-N 3.14Å
181	T	81.5	Confident	82	Confident	41 Å²	41	59.5 Å²	59.5	25%	0.252	31%	0.314	S	S	.	.	H	α-helix	trans	-65.4	-39.5	176	-57.6	0	0	0	0	111.6	R177 D178 S179 R184 M185	R177-T181 WeakPolarHBondContact O-CB 3.4Å; R177-T181 PolarHBondContact O-N 3.29Å; R177-T181 PolarHBondContact O-OG1 2.98Å; D178-T181 PolarHBondContact O-N 3.27Å; S179-T181 VanDerWaalsContact C-N 3.3Å; S179-T181 PolarHBondContact O-N 3.09Å; T181-R184 WeakPolarHBondContact O-CB 3.28Å; T181-R184 PolarHBondContact O-N 3.32Å; T181-M185 HydrophobicContact CG2-CG 4.43Å; T181-M185 WeakPolarHBondContact O-CG 3.37Å; T181-M185 PolarHBondContact O-N 3.23Å
182	A	83.7	Confident	82.7	Confident	56 Å²	56	60.1 Å²	60.1	46%	0.463	32%	0.318	S	S	.	.	H	α-helix	trans	-63.1	-42	175	0	0	0	0	0	112.4	D178 S179 T186	D178-A182 PolarHBondContact O-N 3.21Å; S179-A182 WeakPolarHBondContact O-CB 3.42Å; S179-A182 PolarHBondContact O-N 3.38Å; A182-T186 PolarHBondContact O-N 2.98Å; A182-T186 VanDerWaalsContact O-N 3.08Å; A182-T186 PolarHBondContact O-OG1 3.09Å
183	Y	87.4	Confident	83.9	Confident	90 Å²	90	57 Å²	57	35%	0.353	30%	0.296	S	S	.	.	H	α-helix	trans	-61	-46.2	172.9	-81.1	-81.1	0	0	0	111.3	K42 I43 A46 S179 A180 T186 V187	K42-Y183 HydrophobicContact CB-CD2 4.13Å; K42-Y183 HydrophobicContact CB-CG 4.47Å; K42-Y183 HydrophobicContact CD-CD2 4.12Å; K42-Y183 HydrophobicContact CD-CE2 4.04Å; I43-Y183 HydrophobicContact CG1-CD1 4.37Å; I43-Y183 HydrophobicContact CG1-CE1 4.43Å; A46-Y183 VanDerWaalsContact CB-C 3.46Å; A46-Y183 WeakPolarHBondContact CB-O 3.23Å; S179-Y183 WeakPolarHBondContact O-CD2 3.03Å; S179-Y183 PolarHBondContact O-N 3.11Å; S179-Y183 VanDerWaalsContact O-N 3.09Å; A180-Y183 PolarHBondContact O-N 3.39Å; Y183-T186 PolarHBondContact O-N 2.73Å; Y183-V187 PolarHBondContact O-N 3.21Å
184	R	88.3	Confident	85	Confident	33 Å²	33	55.1 Å²	55.1	13%	0.125	29%	0.288	C	S	.	.	H	α-helix	trans	-55.2	-54.1	175.9	174.2	179.6	75.5	86.1	-3.6	111.9	Y45 Y163 A180 T181 T186 V187 E188	Y45-R184 HydrophobicContact CE1-CB 4.05Å; Y163-R184 HydrophobicContact CE1-CG 4.19Å; Y163-R184 WeakPolarHBondContact OH-CD 3.39Å; Y163-R184 VanDerWaalsContact OH-CG 3.28Å; Y163-R184 WeakPolarHBondContact OH-CG 3.21Å; A180-R184 PolarHBondContact O-N 3.14Å; T181-R184 WeakPolarHBondContact O-CB 3.28Å; T181-R184 PolarHBondContact O-N 3.32Å; R184-T186 PolarHBondContact O-N 3.32Å; R184-V187 PolarHBondContact O-N 3.23Å; R184-V187 VanDerWaalsContact O-N 3.15Å; R184-E188 WeakPolarHBondContact CD-OE1 3.16Å; R184-E188 HydrophobicContact CG-CG 4.37Å; R184-E188 WeakPolarHBondContact CG-OE1 3.42Å; R184-E188 IonicContact CZ-OE1 3.27Å; R184-E188 IonicContact NE-OE1 2.68Å; R184-E188 VanDerWaalsContact NH1-CD 3.33Å; R184-E188 IonicContact NH1-OE1 2.68Å; R184-E188 PolarHBondContact NH1-OE1 2.91Å; R184-E188 IonicContact NH1-OE2 3.27Å; R184-E188 PolarHBondContact NH1-OE2 3.38Å; R184-E188 WeakPolarHBondContact O-CB 3.43Å; R184-E188 WeakPolarHBondContact O-CG 3.41Å; R184-E188 PolarHBondContact O-N 3.12Å
185	M	85.1	Confident	86.2	Confident	63 Å²	63	48.9 Å²	48.9	31%	0.31	26%	0.259	S	S	.	.	H	α-helix	trans	-59.1	-37.5	-179.2	-68.1	-59.4	-165.3	0	0	112.1	T181 E188 V189	T181-M185 HydrophobicContact CG2-CG 4.43Å; T181-M185 WeakPolarHBondContact O-CG 3.37Å; T181-M185 PolarHBondContact O-N 3.23Å; M185-E188 PolarHBondContact O-N 3.22Å; M185-V189 VanDerWaalsContact O-CG2 3.23Å; M185-V189 WeakPolarHBondContact O-CG2 3.17Å; M185-V189 PolarHBondContact O-N 3.48Å
186	T	88.8	Confident	87	Confident	83 Å²	83	41.5 Å²	41.5	51%	0.509	23%	0.227	S	C	.	.	H	α-helix	trans	-63.9	-46.2	177	-55.2	0	0	0	0	111.4	A182 Y183 R184 V189 L190	A182-T186 PolarHBondContact O-N 2.98Å; A182-T186 VanDerWaalsContact O-N 3.08Å; A182-T186 PolarHBondContact O-OG1 3.09Å; Y183-T186 PolarHBondContact O-N 2.73Å; R184-T186 PolarHBondContact O-N 3.32Å; T186-V189 PolarHBondContact O-N 3.34Å; T186-L190 HydrophobicContact CG2-CD1 4.46Å; T186-L190 WeakPolarHBondContact O-CG 3.45Å; T186-L190 PolarHBondContact O-N 2.96Å
187	V	92.1	Very high	87.7	Confident	32 Å²	32	41.6 Å²	41.6	19%	0.194	23%	0.232	C	C	.	.	H	α-helix	trans	-68	-37.3	178.8	172	0	0	0	0	111.7	A46 A50 Y183 R184 L190 G191	A46-V187 HydrophobicContact CB-CB 4.12Å; A46-V187 HydrophobicContact CB-CG2 3.68Å; A46-V187 WeakPolarHBondContact O-CG1 3.46Å; A50-V187 HydrophobicContact CB-CG1 3.91Å; Y183-V187 PolarHBondContact O-N 3.21Å; R184-V187 PolarHBondContact O-N 3.23Å; R184-V187 VanDerWaalsContact O-N 3.15Å; V187-L190 PolarHBondContact O-N 3.19Å; V187-G191 PolarHBondContact O-N 3.47Å
188	E	90.4	Very high	88.5	Confident	11 Å²	11	40.4 Å²	40.4	5%	0.051	23%	0.229	C	C	.	.	H	α-helix	trans	-58.8	-46.3	173.8	-87.6	-175.1	-150.7	0	0	112.5	Q53 R184 M185 G191 T192	Q53-E188 WeakPolarHBondContact CB-O 3.36Å; Q53-E188 HydrophobicContact CG-CB 3.63Å; Q53-E188 HydrophobicContact CG-CG 3.61Å; Q53-E188 PolarHBondContact NE2-OE2 2.74Å; Q53-E188 VanDerWaalsContact NE2-OE2 3.09Å; R184-E188 WeakPolarHBondContact CD-OE1 3.16Å; R184-E188 HydrophobicContact CG-CG 4.37Å; R184-E188 WeakPolarHBondContact CG-OE1 3.42Å; R184-E188 IonicContact CZ-OE1 3.27Å; R184-E188 IonicContact NE-OE1 2.68Å; R184-E188 VanDerWaalsContact NH1-CD 3.33Å; R184-E188 IonicContact NH1-OE1 2.68Å; R184-E188 PolarHBondContact NH1-OE1 2.91Å; R184-E188 IonicContact NH1-OE2 3.27Å; R184-E188 PolarHBondContact NH1-OE2 3.38Å; R184-E188 WeakPolarHBondContact O-CB 3.43Å; R184-E188 WeakPolarHBondContact O-CG 3.41Å; R184-E188 PolarHBondContact O-N 3.12Å; M185-E188 PolarHBondContact O-N 3.22Å; E188-G191 WeakPolarHBondContact O-CA 3.31Å; E188-G191 PolarHBondContact O-N 3.45Å; E188-G191 VanDerWaalsContact O-N 3.14Å; E188-T192 PolarHBondContact O-N 3.4Å
189	V	89.6	Confident	89.1	Confident	36 Å²	36	35.7 Å²	35.7	22%	0.218	20%	0.204	C	C	.	.	H	α-helix	trans	-65.4	-41.2	175.9	172.1	0	0	0	0	111.5	M185 T186 G191 T192 V193 T338 I341	M185-V189 VanDerWaalsContact O-CG2 3.23Å; M185-V189 WeakPolarHBondContact O-CG2 3.17Å; M185-V189 PolarHBondContact O-N 3.48Å; T186-V189 PolarHBondContact O-N 3.34Å; V189-G191 PolarHBondContact O-N 2.88Å; V189-T192 PolarHBondContact O-N 3.28Å; V189-T192 PolarHBondContact O-OG1 3.15Å; V189-V193 PolarHBondContact O-N 2.81Å; V189-T338 HydrophobicContact CG1-CG2 3.5Å; V189-T338 VanDerWaalsContact CG1-CG2 3.5Å; V189-T338 WeakPolarHBondContact CG1-OG1 3.5Å; V189-I341 HydrophobicContact CB-CD1 4.15Å; V189-I341 HydrophobicContact CG1-CD1 3.65Å; V189-I341 HydrophobicContact CG2-CD1 3.56Å
190	L	92.1	Very high	89.2	Confident	99 Å²	99	34 Å²	34	52%	0.518	19%	0.192	S	C	.	.	H	α-helix	trans	-63.1	-32	173.7	-69.1	172.4	0	0	0	111.7	T186 V187 V193 L194 T338	T186-L190 HydrophobicContact CG2-CD1 4.46Å; T186-L190 WeakPolarHBondContact O-CG 3.45Å; T186-L190 PolarHBondContact O-N 2.96Å; V187-L190 PolarHBondContact O-N 3.19Å; L190-V193 PolarHBondContact O-N 2.7Å; L190-L194 WeakPolarHBondContact O-CB 3.18Å; L190-L194 PolarHBondContact O-N 3.2Å; L190-T338 HydrophobicContact CD2-CG2 4.5Å
191	G	93.1	Very high	89.4	Confident	3 Å²	3	37.8 Å²	37.8	3%	0.031	21%	0.209	C	C	.	.	H	α-helix	trans	-61.8	-40.7	174.1	0	0	0	0	0	113.5	I54 V187 E188 V189 L194 S195	I54-G191 VanDerWaalsContact CG1-O 3.27Å; I54-G191 WeakPolarHBondContact CG1-O 3.46Å; V187-G191 PolarHBondContact O-N 3.47Å; E188-G191 WeakPolarHBondContact O-CA 3.31Å; E188-G191 PolarHBondContact O-N 3.45Å; E188-G191 VanDerWaalsContact O-N 3.14Å; V189-G191 PolarHBondContact O-N 2.88Å; G191-L194 PolarHBondContact O-N 3.18Å; G191-S195 WeakPolarHBondContact O-CB 3.42Å; G191-S195 PolarHBondContact O-N 3.43Å
192	T	90.8	Very high	89.7	Confident	28 Å²	28	38 Å²	38	17%	0.172	21%	0.208	C	C	.	.	H	α-helix	trans	-66.4	-40.9	177.8	62.8	0	0	0	0	111.9	Q53 C57 E188 V189 S195 T196	Q53-T192 HydrophobicContact CB-CG2 3.82Å; Q53-T192 HydrophobicContact CG-CG2 4.49Å; C57-T192 HydrophobicContact CB-CG2 4.32Å; E188-T192 PolarHBondContact O-N 3.4Å; V189-T192 PolarHBondContact O-N 3.28Å; V189-T192 PolarHBondContact O-OG1 3.15Å; T192-S195 PolarHBondContact O-N 2.76Å; T192-T196 PolarHBondContact O-N 3.13Å; T192-T196 VanDerWaalsContact O-N 3.09Å; T192-T196 PolarHBondContact O-OG1 3.42Å; T192-T196 VanDerWaalsContact O-OG1 3.04Å
193	V	93.2	Very high	89.6	Confident	21 Å²	21	35.4 Å²	35.4	13%	0.127	19%	0.187	C	C	.	.	H	α-helix	trans	-61.7	-46.6	174	179.3	0	0	0	0	110.4	V189 L190 S195 T196 A197 L331 M334 L335 T338	V189-V193 PolarHBondContact O-N 2.81Å; L190-V193 PolarHBondContact O-N 2.7Å; V193-S195 PolarHBondContact O-N 3.43Å; V193-T196 PolarHBondContact O-N 3.33Å; V193-A197 WeakPolarHBondContact O-CB 3.29Å; V193-A197 PolarHBondContact O-N 3.41Å; V193-L331 HydrophobicContact CG1-CD1 4.24Å; V193-M334 HydrophobicContact CG2-CB 4.11Å; V193-L335 HydrophobicContact CG1-CD1 4.29Å; V193-T338 WeakPolarHBondContact CG2-OG1 3.19Å
194	L	93.9	Very high	88.9	Confident	67 Å²	67	32 Å²	32	35%	0.351	18%	0.179	S	C	.	.	H	α-helix	trans	-64.8	-39.5	-178.7	-173.5	60.7	0	0	0	112.2	L190 G191 A197 I198 M251	L190-L194 WeakPolarHBondContact O-CB 3.18Å; L190-L194 PolarHBondContact O-N 3.2Å; G191-L194 PolarHBondContact O-N 3.18Å; L194-A197 PolarHBondContact O-N 3.34Å; L194-I198 HydrophobicContact CD1-CD1 4.02Å; L194-I198 HydrophobicContact CD1-CG1 4.17Å; L194-I198 HydrophobicContact CD2-CD1 4.42Å; L194-I198 HydrophobicContact CG-CD1 3.74Å; L194-I198 HydrophobicContact CG-CG1 4.32Å; L194-I198 WeakPolarHBondContact O-CB 3.47Å; L194-I198 WeakPolarHBondContact O-CG1 3.14Å; L194-I198 PolarHBondContact O-N 3Å; L194-M251 HydrophobicContact CD2-CE 3.2Å; L194-M251 HydrophobicContact CD2-SD 3.6Å; L194-M251 HydrophobicContact CG-CE 4.42Å; L194-M251 HydrophobicContact CG-SD 4.28Å
195	S	92.2	Very high	88	Confident	0 Å²	0	37 Å²	37	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-58.6	-50.7	173.4	-179.3	0	0	0	0	112.1	I54 A58 G191 T192 V193 A197 I198 Q199	I54-S195 VanDerWaalsContact O-CB 3.23Å; I54-S195 WeakPolarHBondContact O-CB 3.44Å; I54-S195 PolarHBondContact O-OG 3.38Å; A58-S195 WeakPolarHBondContact CB-OG 3.49Å; A58-S195 PolarHBondContact N-OG 2.92Å; G191-S195 WeakPolarHBondContact O-CB 3.42Å; G191-S195 PolarHBondContact O-N 3.43Å; T192-S195 PolarHBondContact O-N 2.76Å; V193-S195 PolarHBondContact O-N 3.43Å; S195-A197 VanDerWaalsContact C-N 3.27Å; S195-A197 PolarHBondContact O-N 2.9Å; S195-I198 PolarHBondContact O-N 3.44Å; S195-Q199 WeakPolarHBondContact O-CB 3.21Å; S195-Q199 PolarHBondContact O-N 3.47Å
196	T	90.3	Very high	87.1	Confident	0 Å²	0	34.3 Å²	34.3	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-63.5	-35.8	178.6	-55.6	0	0	0	0	111.4	C57 T192 V193 G200 L330 L331 M334	C57-T196 PolarHBondContact SG-OG1 3.43Å; C57-T196 VanDerWaalsContact SG-OG1 3.35Å; T192-T196 PolarHBondContact O-N 3.13Å; T192-T196 VanDerWaalsContact O-N 3.09Å; T192-T196 PolarHBondContact O-OG1 3.42Å; T192-T196 VanDerWaalsContact O-OG1 3.04Å; V193-T196 PolarHBondContact O-N 3.33Å; T196-G200 WeakPolarHBondContact O-CA 3.48Å; T196-G200 PolarHBondContact O-N 3.46Å; T196-L330 HydrophobicContact CG2-CB 3.8Å; T196-L331 HydrophobicContact CG2-CB 4.41Å; T196-M334 HydrophobicContact CG2-CG 4.23Å
197	A	92.1	Very high	86	Confident	26 Å²	26	32.3 Å²	32.3	22%	0.215	18%	0.181	C	C	.	.	H	α-helix	trans	-67.9	-49.7	175.1	0	0	0	0	0	112.2	V193 L194 S195 Q201 L331	V193-A197 WeakPolarHBondContact O-CB 3.29Å; V193-A197 PolarHBondContact O-N 3.41Å; L194-A197 PolarHBondContact O-N 3.34Å; S195-A197 VanDerWaalsContact C-N 3.27Å; S195-A197 PolarHBondContact O-N 2.9Å; A197-Q201 VanDerWaalsContact O-CB 3.26Å; A197-Q201 WeakPolarHBondContact O-CB 3.34Å; A197-Q201 VanDerWaalsContact O-CG 3.23Å; A197-Q201 WeakPolarHBondContact O-CG 3.48Å; A197-Q201 PolarHBondContact O-N 3.47Å; A197-L331 HydrophobicContact CB-CD1 3.8Å
198	I	92.1	Very high	84.5	Confident	20 Å²	20	31 Å²	31	10%	0.103	17%	0.173	C	C	.	.	H	α-helix	trans	-61.6	-54.2	-179.6	-69.2	166.5	0	0	0	109.7	L194 S195 I202 V247 I248 M251	L194-I198 HydrophobicContact CD1-CD1 4.02Å; L194-I198 HydrophobicContact CD1-CG1 4.17Å; L194-I198 HydrophobicContact CD2-CD1 4.42Å; L194-I198 HydrophobicContact CG-CD1 3.74Å; L194-I198 HydrophobicContact CG-CG1 4.32Å; L194-I198 WeakPolarHBondContact O-CB 3.47Å; L194-I198 WeakPolarHBondContact O-CG1 3.14Å; L194-I198 PolarHBondContact O-N 3Å; S195-I198 PolarHBondContact O-N 3.44Å; I198-I202 HydrophobicContact CG2-CD1 3.71Å; I198-I202 VanDerWaalsContact O-CB 3.28Å; I198-I202 WeakPolarHBondContact O-CB 3.48Å; I198-I202 WeakPolarHBondContact O-CD1 3Å; I198-I202 WeakPolarHBondContact O-CG1 3.41Å; I198-I202 PolarHBondContact O-N 3.29Å; I198-I202 VanDerWaalsContact O-N 3.13Å; I198-V247 HydrophobicContact CD1-CG1 4.14Å; I198-V247 HydrophobicContact CG1-CG1 4.49Å; I198-V247 HydrophobicContact CG2-CB 4.18Å; I198-V247 HydrophobicContact CG2-CG1 3.99Å; I198-I248 HydrophobicContact CG2-CD1 4.46Å; I198-I248 HydrophobicContact CG2-CG1 4.08Å; I198-M251 HydrophobicContact CD1-SD 3.61Å
199	Q	88.4	Confident	83.2	Confident	0 Å²	0	33.5 Å²	33.5	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-68.6	-40.2	-177.7	-163.6	139.7	23.9	0	0	111	F62 S195 V203	F62-Q199 HydrophobicContact CB-CG 4.32Å; F62-Q199 HydrophobicContact CD1-CG 4.14Å; F62-Q199 HydrophobicContact CD2-CB 3.98Å; F62-Q199 HydrophobicContact CD2-CG 3.56Å; F62-Q199 HydrophobicContact CE1-CG 4.38Å; F62-Q199 HydrophobicContact CE2-CB 3.79Å; F62-Q199 HydrophobicContact CE2-CG 3.82Å; F62-Q199 HydrophobicContact CG-CG 3.73Å; F62-Q199 HydrophobicContact CZ-CB 4.27Å; F62-Q199 HydrophobicContact CZ-CG 4.22Å; S195-Q199 WeakPolarHBondContact O-CB 3.21Å; S195-Q199 PolarHBondContact O-N 3.47Å; Q199-V203 HydrophobicContact CG-CG2 4.04Å; Q199-V203 WeakPolarHBondContact O-CB 3.17Å; Q199-V203 WeakPolarHBondContact O-CG2 3.3Å; Q199-V203 PolarHBondContact O-N 2.84Å
200	G	85.8	Confident	82	Confident	1 Å²	1	33.6 Å²	33.6	1%	0.01	19%	0.192	C	C	.	.	H	α-helix	trans	-63.1	-48.8	179.1	0	0	0	0	0	114.5	T196 G204	T196-G200 WeakPolarHBondContact O-CA 3.48Å; T196-G200 PolarHBondContact O-N 3.46Å; G200-G204 VanDerWaalsContact O-CA 3.26Å; G200-G204 WeakPolarHBondContact O-CA 3.35Å; G200-G204 PolarHBondContact O-N 2.97Å
201	Q	87.4	Confident	80.7	Confident	83 Å²	83	32.4 Å²	32.4	39%	0.388	19%	0.186	S	C	.	.	H	α-helix	trans	-76.7	-36.8	-176.2	-63.6	-59.3	-46.4	0	0	112.3	A197 N205 N328	A197-Q201 VanDerWaalsContact O-CB 3.26Å; A197-Q201 WeakPolarHBondContact O-CB 3.34Å; A197-Q201 VanDerWaalsContact O-CG 3.23Å; A197-Q201 WeakPolarHBondContact O-CG 3.48Å; A197-Q201 PolarHBondContact O-N 3.47Å; Q201-N205 VanDerWaalsContact O-CG 3.25Å; Q201-N205 PolarHBondContact O-ND2 2.93Å; Q201-N205 VanDerWaalsContact O-ND2 3.09Å; Q201-N328 PolarHBondContact NE2-OD1 3.45Å
202	I	86.6	Confident	79.3	Confident	46 Å²	46	37 Å²	37	24%	0.236	22%	0.216	C	C	.	.	H	α-helix	trans	-73.2	-46.8	179.6	-62.6	171.9	0	0	0	110.5	I198 A240 I243 A244 V247	I198-I202 HydrophobicContact CG2-CD1 3.71Å; I198-I202 VanDerWaalsContact O-CB 3.28Å; I198-I202 WeakPolarHBondContact O-CB 3.48Å; I198-I202 WeakPolarHBondContact O-CD1 3Å; I198-I202 WeakPolarHBondContact O-CG1 3.41Å; I198-I202 PolarHBondContact O-N 3.29Å; I198-I202 VanDerWaalsContact O-N 3.13Å; I202-A240 HydrophobicContact CG2-CB 4.31Å; I202-A240 WeakPolarHBondContact CG2-O 3.35Å; I202-I243 HydrophobicContact CG2-CB 4.35Å; I202-I243 HydrophobicContact CG2-CG2 4.2Å; I202-A244 HydrophobicContact CB-CB 4.1Å; I202-A244 HydrophobicContact CD1-CB 4.1Å; I202-A244 HydrophobicContact CG2-CB 4Å; I202-V247 HydrophobicContact CD1-CG2 4.28Å
203	V	81.8	Confident	77.4	Confident	1 Å²	1	40.5 Å²	40.5	1%	0.006	24%	0.241	C	C	.	.	H	α-helix	trans	-75.4	-36.1	-179.5	179.5	0	0	0	0	111.5	Q199 N205 A206 Y241 A244	Q199-V203 HydrophobicContact CG-CG2 4.04Å; Q199-V203 WeakPolarHBondContact O-CB 3.17Å; Q199-V203 WeakPolarHBondContact O-CG2 3.3Å; Q199-V203 PolarHBondContact O-N 2.84Å; V203-N205 PolarHBondContact O-N 3.39Å; V203-A206 PolarHBondContact O-N 3.06Å; V203-Y241 HydrophobicContact CG1-CD2 4.11Å; V203-Y241 HydrophobicContact CG1-CE1 4.11Å; V203-Y241 HydrophobicContact CG1-CE2 3.44Å; V203-Y241 VanDerWaalsContact CG1-CE2 3.44Å; V203-Y241 VanDerWaalsContact CG1-CZ 3.46Å; V203-Y241 HydrophobicContact CG2-CD1 3.79Å; V203-Y241 HydrophobicContact CG2-CD2 4.21Å; V203-Y241 HydrophobicContact CG2-CE1 3.79Å; V203-Y241 HydrophobicContact CG2-CE2 4.2Å; V203-Y241 HydrophobicContact CG2-CG 4.01Å; V203-A244 HydrophobicContact CG2-CB 4.49Å
204	G	72.8	Confident	75.5	Confident	19 Å²	19	46.7 Å²	46.7	20%	0.196	27%	0.269	C	S	.	.	H	α-helix	trans	-59.3	-31.6	179.7	0	0	0	0	0	113.9	G200 A206 H327	G200-G204 VanDerWaalsContact O-CA 3.26Å; G200-G204 WeakPolarHBondContact O-CA 3.35Å; G200-G204 PolarHBondContact O-N 2.97Å; G204-A206 VanDerWaalsContact C-N 3.29Å; G204-A206 PolarHBondContact O-N 2.92Å; G204-H327 VanDerWaalsContact CA-CE1 3.4Å; G204-H327 WeakPolarHBondContact CA-CE1 3.36Å; G204-H327 WeakPolarHBondContact CA-ND1 3.45Å
205	N	69.9	Low	73.2	Confident	137 Å²	137	50.4 Å²	50.4	73%	0.733	29%	0.288	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.2	-13.8	178.3	-71	-18.7	0	0	0	113.9	Q201 V203	Q201-N205 VanDerWaalsContact O-CG 3.25Å; Q201-N205 PolarHBondContact O-ND2 2.93Å; Q201-N205 VanDerWaalsContact O-ND2 3.09Å; V203-N205 PolarHBondContact O-N 3.39Å
206	A	66	Low	70.8	Confident	8 Å²	8	57.9 Å²	57.9	7%	0.066	33%	0.328	C	S	.	.	T	Hydrogen-bonded Turn	trans	-121.4	39.2	-170.9	0	0	0	0	0	112.9	V203 G204 A208 L236 Q237 A240	V203-A206 PolarHBondContact O-N 3.06Å; G204-A206 VanDerWaalsContact C-N 3.29Å; G204-A206 PolarHBondContact O-N 2.92Å; A206-A208 PolarHBondContact O-N 2.96Å; A206-L236 HydrophobicContact CB-CD2 4.35Å; A206-L236 HydrophobicContact CB-CG 4.03Å; A206-Q237 WeakPolarHBondContact O-CA 3.47Å; A206-Q237 VanDerWaalsContact O-CB 3.27Å; A206-Q237 WeakPolarHBondContact O-CB 2.94Å; A206-Q237 WeakPolarHBondContact O-CG 3.43Å; A206-A240 HydrophobicContact CB-CB 3.46Å; A206-A240 VanDerWaalsContact CB-CB 3.46Å
207	H	65.6	Low	68.7	Low	40 Å²	40	63.1 Å²	63.1	19%	0.185	37%	0.365	C	S	.	.	P	Polyproline II helix	trans	-74.5	119.7	-175.9	-151.3	79.3	0	0	0	112.1
208	A	60.3	Low	66.5	Low	4 Å²	4	68.9 Å²	68.9	3%	0.033	39%	0.392	C	S	.	.	P	Polyproline II helix	trans	-70.7	147.3	172.4	0	0	0	0	0	110.8	A206 L233 Q237	A206-A208 PolarHBondContact O-N 2.96Å; A208-L233 HydrophobicContact CB-CB 4.16Å; A208-Q237 HydrophobicContact CB-CB 4.49Å; A208-Q237 VanDerWaalsContact N-OE1 3.13Å
209	P	62.3	Low	64.2	Low	64 Å²	64	74.1 Å²	74.1	42%	0.416	42%	0.416	S	S	.	.	P	Polyproline II helix	trans	-69.2	151.5	179.3	-1.8	23.2	0	0	0	108.5	L230 L233 R455	P209-L230 HydrophobicContact CG-CD1 4.49Å; P209-L233 HydrophobicContact CG-CD2 3.54Å; P209-R455 PolarHBondContact O-NH2 3.44Å
210	C	65.3	Low	62.2	Low	38 Å²	38	79.3 Å²	79.3	26%	0.257	45%	0.452	S	S	.	.	P	Polyproline II helix	trans	-71.9	156.7	172.5	59.5	0	0	0	0	110.7	R455 C457	C210-R455 WeakPolarHBondContact CA-O 3.43Å; C210-C457 HydrophobicContact CB-CB 3.83Å; C210-C457 WeakPolarHBondContact CB-SG 3.46Å; C210-C457 PolarHBondContact O-SG 2.86Å; C210-C457 WeakPolarHBondContact SG-CA 3.48Å; C210-C457 WeakPolarHBondContact SG-CB 3.29Å; C210-C457 CovalentContact SG-SG 2.03Å; C210-C457 PolarHBondContact SG-SG 3.38Å
211	L	64.4	Low	60.3	Low	75 Å²	75	86.1 Å²	86.1	39%	0.393	49%	0.488	S	S	.	.	B	Isolated β-bridge	trans	-82.5	121	175.1	-72.1	171.6	0	0	0	109.6	L230 R455 C457	L211-L230 HydrophobicContact CD2-CD1 4.45Å; L211-L230 HydrophobicContact CD2-CD2 3.56Å; L211-R455 HydrophobicContact CD1-CB 4.36Å; L211-R455 PolarHBondContact N-O 3.47Å; L211-C457 PolarHBondContact O-N 3.35Å; L211-C457 PolarHBondContact O-SG 3.05Å; L211-C457 VanDerWaalsContact O-SG 3.42Å
212	P	63.8	Low	58.2	Low	100 Å²	100	88.3 Å²	88.3	65%	0.649	50%	0.498	S	S	*	.	P	Polyproline II helix	trans	-65.2	143.8	173.4	26.6	-31.7	0	0	0	109.9	H214	P212-H214 PolarHBondContact O-N 3.23Å
213	S	52.2	Low	56.4	Low	100 Å²	100	91.2 Å²	91.2	70%	0.699	51%	0.51	S	S	*	.	P	Polyproline II helix	trans	-65	127.7	175.1	-166.8	0	0	0	0	109	N215	S213-N215 PolarHBondContact O-N 3.44Å
214	H	51.7	Low	54.8	Low	152 Å²	152	94.3 Å²	94.3	70%	0.704	53%	0.529	S	S	*	.	S	Bend	trans	-62.9	93.5	-178.1	-114.7	-75.8	0	0	0	109.6	P212	P212-H214 PolarHBondContact O-N 3.23Å
215	N	46.5	Very low	53.7	Low	144 Å²	144	98.3 Å²	98.3	77%	0.77	55%	0.55	S	S	*	.			trans	-137.7	2.6	173	-109.8	7.2	0	0	0	115.7	S213	S213-N215 PolarHBondContact O-N 3.44Å
216	N	41.6	Very low	53.3	Low	157 Å²	157	96.8 Å²	96.8	84%	0.84	54%	0.542	S	S	*	.			trans	-125.4	106.1	168.6	-75.1	-14.2	0	0	0	109.8	D218	N216-D218 PolarHBondContact O-N 3.02Å
217	S	47	Very low	53	Low	110 Å²	110	103.7 Å²	103.7	77%	0.769	57%	0.57	S	S	*	*			trans	-68.2	98.2	161.9	46.7	0	0	0	0	108.6
218	D	44.2	Very low	53	Low	147 Å²	147	109.4 Å²	109.4	79%	0.786	59%	0.591	S	S	*	*			trans	-168.1	139.9	147.4	-92.4	-27.8	0	0	0	111.6	N216	N216-D218 PolarHBondContact O-N 3.02Å
219	H	43.8	Very low	53.2	Low	131 Å²	131	112.3 Å²	112.3	61%	0.606	61%	0.611	S	S	*	*			trans	86.3	90.6	173.4	-64.6	-75.1	0	0	0	120.1	L221 Q222 H223	H219-L221 PolarHBondContact O-N 3.42Å; H219-Q222 HydrophobicContact CB-CB 4Å; H219-H223 PolarHBondContact O-N 2.87Å
220	S	47.7	Very low	53.6	Low	108 Å²	108	111.3 Å²	111.3	76%	0.755	60%	0.602	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.3	-18.4	172	50.7	0	0	0	0	115.6	T224	S220-T224 PolarHBondContact O-OG1 3.47Å
221	L	45.4	Very low	54.1	Low	144 Å²	144	113.6 Å²	113.6	75%	0.754	61%	0.611	S	S	*	*	T	Hydrogen-bonded Turn	trans	-89.7	-32.6	177.4	-146.4	85.5	0	0	0	113	H219 H223	H219-L221 PolarHBondContact O-N 3.42Å; L221-H223 VanDerWaalsContact C-N 3.28Å
222	Q	44.1	Very low	54.6	Low	129 Å²	129	115.5 Å²	115.5	60%	0.603	62%	0.621	S	S	*	*	H	α-helix	trans	-68.3	-31.7	173.9	-151.8	114.7	-14.5	0	0	111.1	H219 T224 N226	H219-Q222 HydrophobicContact CB-CB 4Å; Q222-T224 VanDerWaalsContact C-N 3.35Å; Q222-T224 PolarHBondContact O-N 3.09Å; Q222-N226 VanDerWaalsContact O-CB 3.31Å; Q222-N226 WeakPolarHBondContact O-CB 3.43Å; Q222-N226 PolarHBondContact O-N 3.22Å
223	H	48.8	Very low	55.3	Low	107 Å²	107	113.3 Å²	113.3	50%	0.495	60%	0.604	S	S	.	*	H	α-helix	trans	-62.9	-35.5	178.6	-115.5	-82.7	0	0	0	113.3	H219 L221 K227	H219-H223 PolarHBondContact O-N 2.87Å; L221-H223 VanDerWaalsContact C-N 3.28Å; H223-K227 VanDerWaalsContact O-CB 3.25Å; H223-K227 WeakPolarHBondContact O-CB 3.47Å; H223-K227 PolarHBondContact O-N 3.21Å
224	T	47.4	Very low	56.5	Low	66 Å²	66	108.9 Å²	108.9	41%	0.405	57%	0.572	S	S	.	*	H	α-helix	trans	-75.8	-43.9	-178.4	-24.7	0	0	0	0	111.3	S220 Q222 K227 Y228	S220-T224 PolarHBondContact O-OG1 3.47Å; Q222-T224 VanDerWaalsContact C-N 3.35Å; Q222-T224 PolarHBondContact O-N 3.09Å; T224-K227 WeakPolarHBondContact O-CB 3.05Å; T224-K227 PolarHBondContact O-N 2.93Å; T224-K227 VanDerWaalsContact O-N 3.14Å; T224-Y228 HydrophobicContact CG2-CD2 4.35Å; T224-Y228 HydrophobicContact CG2-CE2 3.65Å; T224-Y228 WeakPolarHBondContact O-CD2 3.42Å; T224-Y228 PolarHBondContact O-N 3.08Å
225	V	50	Low	57.8	Low	104 Å²	104	106 Å²	106	63%	0.63	56%	0.56	S	S	*	*	H	α-helix	trans	-64.2	-40.1	174.8	-180	0	0	0	0	111	K227 S229	V225-K227 PolarHBondContact O-N 3.42Å; V225-S229 WeakPolarHBondContact O-CB 3.49Å; V225-S229 PolarHBondContact O-N 3.37Å
226	N	60.3	Low	59.5	Low	105 Å²	105	103.4 Å²	103.4	56%	0.561	55%	0.546	S	S	*	.	H	α-helix	trans	-65.2	-35.4	171.7	-87.4	-7.2	0	0	0	112.6	Q222 S229 L230	Q222-N226 VanDerWaalsContact O-CB 3.31Å; Q222-N226 WeakPolarHBondContact O-CB 3.43Å; Q222-N226 PolarHBondContact O-N 3.22Å; N226-S229 PolarHBondContact O-N 3.23Å; N226-L230 WeakPolarHBondContact O-CB 3.26Å; N226-L230 PolarHBondContact O-N 2.74Å
227	K	60.4	Low	61.5	Low	152 Å²	152	96.1 Å²	96.1	66%	0.661	51%	0.507	S	S	*	.	H	α-helix	trans	-67	-42.9	178.2	-170.4	176.1	-177.7	179.2	0	112	H223 T224 V225 L230 L231	H223-K227 VanDerWaalsContact O-CB 3.25Å; H223-K227 WeakPolarHBondContact O-CB 3.47Å; H223-K227 PolarHBondContact O-N 3.21Å; T224-K227 WeakPolarHBondContact O-CB 3.05Å; T224-K227 PolarHBondContact O-N 2.93Å; T224-K227 VanDerWaalsContact O-N 3.14Å; V225-K227 PolarHBondContact O-N 3.42Å; K227-L230 PolarHBondContact O-N 2.87Å; K227-L231 VanDerWaalsContact O-CB 3.27Å; K227-L231 WeakPolarHBondContact O-CB 3.18Å; K227-L231 PolarHBondContact O-N 3Å
228	Y	65.1	Low	63.4	Low	161 Å²	161	93.7 Å²	93.7	63%	0.631	48%	0.481	S	S	*	.	H	α-helix	trans	-67.1	-41.5	175	-66.6	-68.1	0	0	0	112	T224 L231 L232	T224-Y228 HydrophobicContact CG2-CD2 4.35Å; T224-Y228 HydrophobicContact CG2-CE2 3.65Å; T224-Y228 WeakPolarHBondContact O-CD2 3.42Å; T224-Y228 PolarHBondContact O-N 3.08Å; Y228-L231 PolarHBondContact O-N 3.31Å; Y228-L232 VanDerWaalsContact O-CB 3.3Å; Y228-L232 WeakPolarHBondContact O-CB 3.41Å; Y228-L232 PolarHBondContact O-N 3.06Å
229	S	66.3	Low	65.5	Low	64 Å²	64	90.3 Å²	90.3	45%	0.448	46%	0.463	S	S	.	.	H	α-helix	trans	-63.6	-41.1	175.2	-175.4	0	0	0	0	112.3	V225 N226 L232 L233	V225-S229 WeakPolarHBondContact O-CB 3.49Å; V225-S229 PolarHBondContact O-N 3.37Å; N226-S229 PolarHBondContact O-N 3.23Å; S229-L232 PolarHBondContact O-N 3.26Å; S229-L233 PolarHBondContact O-N 3.09Å
230	L	70.7	Confident	67.6	Low	44 Å²	44	84.3 Å²	84.3	23%	0.23	44%	0.436	C	S	.	.	H	α-helix	trans	-67.1	-41.6	175.8	-178.4	72.9	0	0	0	112.2	P209 L211 N226 K227 L232 L233 L234	P209-L230 HydrophobicContact CG-CD1 4.49Å; L211-L230 HydrophobicContact CD2-CD1 4.45Å; L211-L230 HydrophobicContact CD2-CD2 3.56Å; N226-L230 WeakPolarHBondContact O-CB 3.26Å; N226-L230 PolarHBondContact O-N 2.74Å; K227-L230 PolarHBondContact O-N 2.87Å; L230-L232 VanDerWaalsContact C-N 3.33Å; L230-L233 PolarHBondContact O-N 3.1Å; L230-L234 WeakPolarHBondContact O-CB 3.22Å; L230-L234 PolarHBondContact O-N 3.46Å
231	L	74.3	Confident	69.7	Low	85 Å²	85	79.2 Å²	79.2	45%	0.445	40%	0.4	S	S	.	.	H	α-helix	trans	-63.1	-42.5	175	-171.6	76.8	0	0	0	110.4	K227 Y228 L234 M235	K227-L231 VanDerWaalsContact O-CB 3.27Å; K227-L231 WeakPolarHBondContact O-CB 3.18Å; K227-L231 PolarHBondContact O-N 3Å; Y228-L231 PolarHBondContact O-N 3.31Å; L231-L234 PolarHBondContact O-N 3.47Å; L231-M235 HydrophobicContact CD1-CE 4.42Å; L231-M235 HydrophobicContact CD2-CE 3.94Å; L231-M235 HydrophobicContact CG-CE 3.94Å; L231-M235 HydrophobicContact CG-SD 4.47Å; L231-M235 WeakPolarHBondContact O-CB 3.49Å; L231-M235 VanDerWaalsContact O-CG 3.27Å; L231-M235 WeakPolarHBondContact O-CG 3.21Å; L231-M235 PolarHBondContact O-N 3.4Å
232	L	76.3	Confident	71.9	Confident	116 Å²	116	74.3 Å²	74.3	61%	0.607	37%	0.374	S	S	*	.	H	α-helix	trans	-62.5	-43.9	176	-174.8	70.2	0	0	0	111.7	Y228 S229 L230 M235 L236	Y228-L232 VanDerWaalsContact O-CB 3.3Å; Y228-L232 WeakPolarHBondContact O-CB 3.41Å; Y228-L232 PolarHBondContact O-N 3.06Å; S229-L232 PolarHBondContact O-N 3.26Å; L230-L232 VanDerWaalsContact C-N 3.33Å; L232-M235 PolarHBondContact O-N 2.86Å; L232-L236 WeakPolarHBondContact O-CB 3.26Å; L232-L236 PolarHBondContact O-N 3.17Å
233	L	76.7	Confident	74.2	Confident	53 Å²	53	72.8 Å²	72.8	28%	0.277	37%	0.369	S	S	.	.	H	α-helix	trans	-69	-35.5	177.2	-125.1	68.5	0	0	0	112.5	A208 P209 S229 L230 L236 Q237	A208-L233 HydrophobicContact CB-CB 4.16Å; P209-L233 HydrophobicContact CG-CD2 3.54Å; S229-L233 PolarHBondContact O-N 3.09Å; L230-L233 PolarHBondContact O-N 3.1Å; L233-L236 PolarHBondContact O-N 2.79Å; L233-Q237 WeakPolarHBondContact O-CB 3.35Å; L233-Q237 PolarHBondContact O-N 3.11Å
234	L	77.7	Confident	76.2	Confident	8 Å²	8	67.7 Å²	67.7	4%	0.042	35%	0.346	C	S	.	.	H	α-helix	trans	-65.1	-41.5	172.2	-176.3	103	0	0	0	111.1	L230 L231 L236 Q237 R238	L230-L234 WeakPolarHBondContact O-CB 3.22Å; L230-L234 PolarHBondContact O-N 3.46Å; L231-L234 PolarHBondContact O-N 3.47Å; L234-L236 VanDerWaalsContact C-N 3.33Å; L234-Q237 PolarHBondContact O-N 3.39Å; L234-R238 WeakPolarHBondContact O-CB 3.33Å; L234-R238 VanDerWaalsContact O-CG 3.31Å; L234-R238 WeakPolarHBondContact O-CG 3.36Å; L234-R238 PolarHBondContact O-N 2.98Å
235	M	79.3	Confident	78.4	Confident	90 Å²	90	64.6 Å²	64.6	44%	0.443	33%	0.326	S	S	.	.	H	α-helix	trans	-62.6	-41.1	173.7	-74.4	177	175.6	0	0	111.2	L231 L232 R238 N239	L231-M235 HydrophobicContact CD1-CE 4.42Å; L231-M235 HydrophobicContact CD2-CE 3.94Å; L231-M235 HydrophobicContact CG-CE 3.94Å; L231-M235 HydrophobicContact CG-SD 4.47Å; L231-M235 WeakPolarHBondContact O-CB 3.49Å; L231-M235 VanDerWaalsContact O-CG 3.27Å; L231-M235 WeakPolarHBondContact O-CG 3.21Å; L231-M235 PolarHBondContact O-N 3.4Å; L232-M235 PolarHBondContact O-N 2.86Å; M235-R238 PolarHBondContact O-N 3.06Å; M235-N239 VanDerWaalsContact O-CB 3.32Å; M235-N239 WeakPolarHBondContact O-CB 3.39Å; M235-N239 PolarHBondContact O-N 3.22Å; M235-N239 PolarHBondContact O-ND2 3.12Å; M235-N239 PolarHBondContact O-OD1 3.4Å
236	L	82.6	Confident	80.5	Confident	90 Å²	90	61.8 Å²	61.8	47%	0.471	31%	0.314	S	S	.	.	H	α-helix	trans	-62	-43.2	175	-170.7	67.8	0	0	0	111.6	A206 L232 L233 L234 N239 A240	A206-L236 HydrophobicContact CB-CD2 4.35Å; A206-L236 HydrophobicContact CB-CG 4.03Å; L232-L236 WeakPolarHBondContact O-CB 3.26Å; L232-L236 PolarHBondContact O-N 3.17Å; L233-L236 PolarHBondContact O-N 2.79Å; L234-L236 VanDerWaalsContact C-N 3.33Å; L236-N239 PolarHBondContact O-N 3.4Å; L236-A240 WeakPolarHBondContact O-CB 3.44Å; L236-A240 PolarHBondContact O-N 3.48Å
237	Q	83	Confident	82.1	Confident	5 Å²	5	59.5 Å²	59.5	2%	0.023	30%	0.304	C	S	.	.	H	α-helix	trans	-64.6	-44.7	176.6	-168.8	172.3	-6.6	0	0	111.8	V70 A206 A208 L233 L234 N239 A240 Y241	V70-Q237 HydrophobicContact CG2-CG 4.18Å; A206-Q237 WeakPolarHBondContact O-CA 3.47Å; A206-Q237 VanDerWaalsContact O-CB 3.27Å; A206-Q237 WeakPolarHBondContact O-CB 2.94Å; A206-Q237 WeakPolarHBondContact O-CG 3.43Å; A208-Q237 HydrophobicContact CB-CB 4.49Å; A208-Q237 VanDerWaalsContact N-OE1 3.13Å; L233-Q237 WeakPolarHBondContact O-CB 3.35Å; L233-Q237 PolarHBondContact O-N 3.11Å; L234-Q237 PolarHBondContact O-N 3.39Å; Q237-N239 VanDerWaalsContact C-N 3.33Å; Q237-N239 PolarHBondContact O-N 2.99Å; Q237-A240 WeakPolarHBondContact O-CB 3.4Å; Q237-A240 PolarHBondContact O-N 3.04Å; Q237-Y241 HydrophobicContact CG-CD2 4.24Å; Q237-Y241 HydrophobicContact CG-CE2 4.09Å; Q237-Y241 WeakPolarHBondContact O-CD2 3.46Å; Q237-Y241 PolarHBondContact O-N 3.38Å; Q237-Y241 VanDerWaalsContact O-N 3.09Å
238	R	87.2	Confident	83.7	Confident	58 Å²	58	52.4 Å²	52.4	22%	0.219	27%	0.273	C	S	.	.	H	α-helix	trans	-57.8	-46.6	173.7	-74.5	173.5	178.4	-176.1	-1.4	111.2	V70 V134 L234 M235 A240 Y241 M242	V70-R238 HydrophobicContact CG1-CB 4.49Å; V70-R238 HydrophobicContact CG1-CG 3.47Å; V70-R238 VanDerWaalsContact CG1-CG 3.47Å; V70-R238 PolarHBondContact O-NH2 2.87Å; V134-R238 HydrophobicContact CG2-CG 4.05Å; L234-R238 WeakPolarHBondContact O-CB 3.33Å; L234-R238 VanDerWaalsContact O-CG 3.31Å; L234-R238 WeakPolarHBondContact O-CG 3.36Å; L234-R238 PolarHBondContact O-N 2.98Å; M235-R238 PolarHBondContact O-N 3.06Å; R238-A240 VanDerWaalsContact C-N 3.32Å; R238-A240 PolarHBondContact O-N 3.25Å; R238-Y241 PolarHBondContact O-N 3.42Å; R238-M242 WeakPolarHBondContact O-CG 3.28Å; R238-M242 PolarHBondContact O-N 2.98Å
239	N	88.3	Confident	85.1	Confident	76 Å²	76	45.2 Å²	45.2	41%	0.406	25%	0.247	S	C	.	.	H	α-helix	trans	-63.3	-38.1	177.5	-69.4	-7.9	0	0	0	111.8	M235 L236 Q237 M242 I243	M235-N239 VanDerWaalsContact O-CB 3.32Å; M235-N239 WeakPolarHBondContact O-CB 3.39Å; M235-N239 PolarHBondContact O-N 3.22Å; M235-N239 PolarHBondContact O-ND2 3.12Å; M235-N239 PolarHBondContact O-OD1 3.4Å; L236-N239 PolarHBondContact O-N 3.4Å; Q237-N239 VanDerWaalsContact C-N 3.33Å; Q237-N239 PolarHBondContact O-N 2.99Å; N239-M242 HydrophobicContact CB-CE 4.38Å; N239-M242 PolarHBondContact O-N 2.87Å; N239-M242 WeakPolarHBondContact OD1-CE 3.37Å; N239-I243 WeakPolarHBondContact O-CB 3.24Å; N239-I243 WeakPolarHBondContact O-CD1 3.27Å; N239-I243 WeakPolarHBondContact O-CG1 3.15Å; N239-I243 PolarHBondContact O-N 3.28Å
240	A	88.8	Confident	86.4	Confident	6 Å²	6	46.1 Å²	46.1	5%	0.05	25%	0.253	C	S	.	.	H	α-helix	trans	-63.2	-43	176.4	0	0	0	0	0	112.4	I202 A206 L236 Q237 R238 M242 I243 A244	I202-A240 HydrophobicContact CG2-CB 4.31Å; I202-A240 WeakPolarHBondContact CG2-O 3.35Å; A206-A240 HydrophobicContact CB-CB 3.46Å; A206-A240 VanDerWaalsContact CB-CB 3.46Å; L236-A240 WeakPolarHBondContact O-CB 3.44Å; L236-A240 PolarHBondContact O-N 3.48Å; Q237-A240 WeakPolarHBondContact O-CB 3.4Å; Q237-A240 PolarHBondContact O-N 3.04Å; R238-A240 VanDerWaalsContact C-N 3.32Å; R238-A240 PolarHBondContact O-N 3.25Å; A240-M242 VanDerWaalsContact C-N 3.35Å; A240-I243 PolarHBondContact O-N 2.91Å; A240-A244 WeakPolarHBondContact O-CB 3.22Å; A240-A244 PolarHBondContact O-N 3.38Å
241	Y	90.2	Very high	87.4	Confident	0 Å²	0	46.3 Å²	46.3	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-62.2	-41.6	172.6	-84.5	-77.8	0	0	0	112.1	F62 L65 Y66 V70 W132 V203 Q237 R238 A244 S245	F62-Y241 HydrophobicContact CB-CE1 4.32Å; L65-Y241 WeakPolarHBondContact CD2-OH 3.24Å; Y66-Y241 AromaticContact CD2-CD1 3.82Å; Y66-Y241 HydrophobicContact CD2-CD1 3.82Å; Y66-Y241 AromaticContact CD2-CD2 3.78Å; Y66-Y241 HydrophobicContact CD2-CD2 3.78Å; Y66-Y241 HydrophobicContact CD2-CE1 4.06Å; Y66-Y241 HydrophobicContact CD2-CE2 4.03Å; Y66-Y241 AromaticContact CD2-CG 3.67Å; Y66-Y241 HydrophobicContact CD2-CG 3.67Å; Y66-Y241 HydrophobicContact CE2-CD1 4.44Å; Y66-Y241 HydrophobicContact CE2-CD2 4.2Å; Y66-Y241 AromaticContact CE2-CG 3.98Å; Y66-Y241 HydrophobicContact CE2-CG 3.98Å; V70-Y241 HydrophobicContact CG2-CD2 4.1Å; V70-Y241 HydrophobicContact CG2-CE2 3.72Å; W132-Y241 HydrophobicContact CD2-CD1 4.35Å; W132-Y241 AromaticContact CE3-CD1 3.35Å; W132-Y241 HydrophobicContact CE3-CD1 3.35Å; W132-Y241 AromaticContact CE3-CE1 3.99Å; W132-Y241 HydrophobicContact CE3-CE1 3.99Å; W132-Y241 HydrophobicContact CE3-CG 4.1Å; W132-Y241 HydrophobicContact CH2-CD1 4.36Å; W132-Y241 HydrophobicContact CH2-CE1 4.34Å; W132-Y241 AromaticContact CZ3-CD1 3.36Å; W132-Y241 HydrophobicContact CZ3-CD1 3.36Å; W132-Y241 AromaticContact CZ3-CE1 3.49Å; W132-Y241 HydrophobicContact CZ3-CE1 3.49Å; W132-Y241 VanDerWaalsContact CZ3-CE1 3.49Å; W132-Y241 HydrophobicContact CZ3-CG 4.43Å; V203-Y241 HydrophobicContact CG1-CD2 4.11Å; V203-Y241 HydrophobicContact CG1-CE1 4.11Å; V203-Y241 HydrophobicContact CG1-CE2 3.44Å; V203-Y241 VanDerWaalsContact CG1-CE2 3.44Å; V203-Y241 VanDerWaalsContact CG1-CZ 3.46Å; V203-Y241 HydrophobicContact CG2-CD1 3.79Å; V203-Y241 HydrophobicContact CG2-CD2 4.21Å; V203-Y241 HydrophobicContact CG2-CE1 3.79Å; V203-Y241 HydrophobicContact CG2-CE2 4.2Å; V203-Y241 HydrophobicContact CG2-CG 4.01Å; Q237-Y241 HydrophobicContact CG-CD2 4.24Å; Q237-Y241 HydrophobicContact CG-CE2 4.09Å; Q237-Y241 WeakPolarHBondContact O-CD2 3.46Å; Q237-Y241 PolarHBondContact O-N 3.38Å; Q237-Y241 VanDerWaalsContact O-N 3.09Å; R238-Y241 PolarHBondContact O-N 3.42Å; Y241-A244 PolarHBondContact O-N 3.15Å; Y241-S245 WeakPolarHBondContact O-CB 3.18Å; Y241-S245 PolarHBondContact O-N 2.89Å; Y241-S245 PolarHBondContact O-OG 3.18Å
242	M	92	Very high	88.3	Confident	42 Å²	42	42.5 Å²	42.5	21%	0.207	23%	0.233	C	C	.	.	H	α-helix	trans	-64.4	-43.5	175.6	-69.1	-170.1	-62.5	0	0	112.2	F129 Y133 R238 N239 A240 S245 A246	F129-M242 HydrophobicContact CE2-CB 4.29Å; F129-M242 HydrophobicContact CZ-CB 4.46Å; Y133-M242 HydrophobicContact CD2-SD 3.79Å; R238-M242 WeakPolarHBondContact O-CG 3.28Å; R238-M242 PolarHBondContact O-N 2.98Å; N239-M242 HydrophobicContact CB-CE 4.38Å; N239-M242 PolarHBondContact O-N 2.87Å; N239-M242 WeakPolarHBondContact OD1-CE 3.37Å; A240-M242 VanDerWaalsContact C-N 3.35Å; M242-S245 WeakPolarHBondContact CA-OG 3.4Å; M242-S245 PolarHBondContact O-N 2.96Å; M242-S245 PolarHBondContact O-OG 2.94Å; M242-A246 WeakPolarHBondContact O-CB 3.48Å; M242-A246 PolarHBondContact O-N 3.34Å
243	I	92.3	Very high	89	Confident	97 Å²	97	39.5 Å²	39.5	50%	0.497	22%	0.219	S	C	.	.	H	α-helix	trans	-62.9	-46.6	176.7	-67.8	162.1	0	0	0	110.3	I202 N239 A240 S245 A246 V247	I202-I243 HydrophobicContact CG2-CB 4.35Å; I202-I243 HydrophobicContact CG2-CG2 4.2Å; N239-I243 WeakPolarHBondContact O-CB 3.24Å; N239-I243 WeakPolarHBondContact O-CD1 3.27Å; N239-I243 WeakPolarHBondContact O-CG1 3.15Å; N239-I243 PolarHBondContact O-N 3.28Å; A240-I243 PolarHBondContact O-N 2.91Å; I243-S245 VanDerWaalsContact C-N 3.3Å; I243-S245 PolarHBondContact O-N 3.35Å; I243-A246 PolarHBondContact O-N 2.81Å; I243-A246 VanDerWaalsContact O-N 3.17Å; I243-V247 WeakPolarHBondContact O-CG2 3.35Å; I243-V247 PolarHBondContact O-N 3.43Å
244	A	92.2	Very high	89.7	Confident	0 Å²	0	42 Å²	42	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-58.6	-44	176.1	0	0	0	0	0	111.4	I202 V203 A240 Y241 A246 V247 I248	I202-A244 HydrophobicContact CB-CB 4.1Å; I202-A244 HydrophobicContact CD1-CB 4.1Å; I202-A244 HydrophobicContact CG2-CB 4Å; V203-A244 HydrophobicContact CG2-CB 4.49Å; A240-A244 WeakPolarHBondContact O-CB 3.22Å; A240-A244 PolarHBondContact O-N 3.38Å; Y241-A244 PolarHBondContact O-N 3.15Å; A244-A246 PolarHBondContact O-N 3.43Å; A244-V247 PolarHBondContact O-N 3.3Å; A244-I248 WeakPolarHBondContact O-CG1 3.38Å; A244-I248 PolarHBondContact O-N 3.4Å
245	S	92.7	Very high	90.3	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-64.2	-38.7	176.6	76.4	0	0	0	0	112.4	F129 Y241 M242 I243 V247 I248 C249	F129-S245 VanDerWaalsContact CD2-OG 3.27Å; F129-S245 WeakPolarHBondContact CD2-OG 3.49Å; Y241-S245 WeakPolarHBondContact O-CB 3.18Å; Y241-S245 PolarHBondContact O-N 2.89Å; Y241-S245 PolarHBondContact O-OG 3.18Å; M242-S245 WeakPolarHBondContact CA-OG 3.4Å; M242-S245 PolarHBondContact O-N 2.96Å; M242-S245 PolarHBondContact O-OG 2.94Å; I243-S245 VanDerWaalsContact C-N 3.3Å; I243-S245 PolarHBondContact O-N 3.35Å; S245-V247 PolarHBondContact O-N 3.3Å; S245-I248 PolarHBondContact O-N 3.48Å; S245-C249 WeakPolarHBondContact O-CB 3.27Å; S245-C249 PolarHBondContact O-N 3.39Å; S245-C249 PolarHBondContact O-SG 3.09Å
246	A	94.1	Very high	90.7	Very high	46 Å²	46	38 Å²	38	38%	0.38	21%	0.213	S	C	.	.	H	α-helix	trans	-64.9	-38.5	176.6	0	0	0	0	0	112.3	F129 M242 I243 A244 C249 S250	F129-A246 HydrophobicContact CE2-CB 4.28Å; M242-A246 WeakPolarHBondContact O-CB 3.48Å; M242-A246 PolarHBondContact O-N 3.34Å; I243-A246 PolarHBondContact O-N 2.81Å; I243-A246 VanDerWaalsContact O-N 3.17Å; A244-A246 PolarHBondContact O-N 3.43Å; A246-C249 WeakPolarHBondContact O-CB 3.04Å; A246-C249 PolarHBondContact O-N 3.46Å; A246-S250 PolarHBondContact O-N 3.23Å
247	V	94.9	Very high	90.9	Very high	57 Å²	57	37.9 Å²	37.9	35%	0.345	21%	0.213	S	C	.	.	H	α-helix	trans	-64.6	-47.4	174	175.7	0	0	0	0	110.5	I198 I202 I243 A244 S245 C249 S250 M251	I198-V247 HydrophobicContact CD1-CG1 4.14Å; I198-V247 HydrophobicContact CG1-CG1 4.49Å; I198-V247 HydrophobicContact CG2-CB 4.18Å; I198-V247 HydrophobicContact CG2-CG1 3.99Å; I202-V247 HydrophobicContact CD1-CG2 4.28Å; I243-V247 WeakPolarHBondContact O-CG2 3.35Å; I243-V247 PolarHBondContact O-N 3.43Å; A244-V247 PolarHBondContact O-N 3.3Å; S245-V247 PolarHBondContact O-N 3.3Å; V247-C249 VanDerWaalsContact C-N 3.31Å; V247-C249 PolarHBondContact O-N 3.2Å; V247-S250 PolarHBondContact O-N 3.11Å; V247-M251 WeakPolarHBondContact O-CG 3.37Å; V247-M251 PolarHBondContact O-N 3.01Å
248	I	94.1	Very high	91.2	Very high	2 Å²	2	39.6 Å²	39.6	1%	0.01	22%	0.223	C	C	.	.	H	α-helix	trans	-60	-42.6	176.1	-69.4	169.2	0	0	0	111	I54 T55 A58 Y128 I198 A244 S245 M251 Y252	I54-I248 HydrophobicContact CG2-CB 4.39Å; I54-I248 HydrophobicContact CG2-CD1 4.45Å; I54-I248 HydrophobicContact CG2-CG1 4.06Å; I54-I248 HydrophobicContact CG2-CG2 3.65Å; T55-I248 HydrophobicContact CG2-CG2 3.94Å; A58-I248 HydrophobicContact CB-CD1 4.25Å; Y128-I248 HydrophobicContact CD1-CG2 4.41Å; Y128-I248 HydrophobicContact CE1-CB 4.02Å; Y128-I248 HydrophobicContact CE1-CD1 4.42Å; Y128-I248 HydrophobicContact CE1-CG2 3.67Å; Y128-I248 WeakPolarHBondContact OH-CD1 3.22Å; I198-I248 HydrophobicContact CG2-CD1 4.46Å; I198-I248 HydrophobicContact CG2-CG1 4.08Å; A244-I248 WeakPolarHBondContact O-CG1 3.38Å; A244-I248 PolarHBondContact O-N 3.4Å; S245-I248 PolarHBondContact O-N 3.48Å; I248-M251 WeakPolarHBondContact O-CB 3.43Å; I248-M251 PolarHBondContact O-N 3.42Å; I248-Y252 PolarHBondContact O-N 3.33Å
249	C	93.5	Very high	91.1	Very high	11 Å²	11	37 Å²	37	7%	0.074	21%	0.214	C	C	.	.	H	α-helix	trans	-59	-45.5	174.6	-81.5	0	0	0	0	112.6	V125 S245 A246 V247 M251 Y252 V253	V125-C249 HydrophobicContact CG1-CB 3.53Å; V125-C249 PolarHBondContact O-SG 3.39Å; S245-C249 WeakPolarHBondContact O-CB 3.27Å; S245-C249 PolarHBondContact O-N 3.39Å; S245-C249 PolarHBondContact O-SG 3.09Å; A246-C249 WeakPolarHBondContact O-CB 3.04Å; A246-C249 PolarHBondContact O-N 3.46Å; V247-C249 VanDerWaalsContact C-N 3.31Å; V247-C249 PolarHBondContact O-N 3.2Å; C249-M251 VanDerWaalsContact C-N 3.34Å; C249-M251 PolarHBondContact O-N 2.81Å; C249-Y252 WeakPolarHBondContact O-CB 3.49Å; C249-Y252 PolarHBondContact O-N 3.08Å; C249-V253 WeakPolarHBondContact O-CG2 3.28Å; C249-V253 PolarHBondContact O-N 3.45Å; C249-V253 VanDerWaalsContact O-N 3.07Å
250	S	93.3	Very high	90.8	Very high	82 Å²	82	37.9 Å²	37.9	57%	0.573	21%	0.214	S	C	*	.	H	α-helix	trans	-62	-42.7	176.1	-179.1	0	0	0	0	111.5	A246 V247 Y252 V253 L254	A246-S250 PolarHBondContact O-N 3.23Å; V247-S250 PolarHBondContact O-N 3.11Å; S250-Y252 PolarHBondContact O-N 2.92Å; S250-V253 PolarHBondContact O-N 2.9Å; S250-L254 WeakPolarHBondContact O-CB 3.34Å; S250-L254 PolarHBondContact O-N 3.41Å
251	M	92.5	Very high	90.4	Very high	48 Å²	48	42 Å²	42	24%	0.236	24%	0.243	C	C	.	.	H	α-helix	trans	-63.1	-40.4	174.7	-71.7	-158.5	63.4	0	0	112.8	I54 L194 I198 V247 I248 C249 L254 C255	I54-M251 HydrophobicContact CD1-CE 4.36Å; L194-M251 HydrophobicContact CD2-CE 3.2Å; L194-M251 HydrophobicContact CD2-SD 3.6Å; L194-M251 HydrophobicContact CG-CE 4.42Å; L194-M251 HydrophobicContact CG-SD 4.28Å; I198-M251 HydrophobicContact CD1-SD 3.61Å; V247-M251 WeakPolarHBondContact O-CG 3.37Å; V247-M251 PolarHBondContact O-N 3.01Å; I248-M251 WeakPolarHBondContact O-CB 3.43Å; I248-M251 PolarHBondContact O-N 3.42Å; C249-M251 VanDerWaalsContact C-N 3.34Å; C249-M251 PolarHBondContact O-N 2.81Å; M251-L254 PolarHBondContact O-N 2.67Å; M251-C255 PolarHBondContact O-N 3.37Å; M251-C255 PolarHBondContact O-SG 3.04Å
252	Y	91.8	Very high	89.8	Confident	5 Å²	5	43 Å²	43	2%	0.02	25%	0.253	C	S	.	.	H	α-helix	trans	-56.3	-52.9	175.1	-165.8	-57.5	0	0	0	110.5	P51 T55 T121 V125 Q156 F159 I248 C249 S250 L254 C255 A256	P51-Y252 HydrophobicContact CB-CD1 4.21Å; P51-Y252 HydrophobicContact CB-CD2 3.5Å; P51-Y252 HydrophobicContact CB-CE1 4.22Å; P51-Y252 HydrophobicContact CB-CE2 3.51Å; P51-Y252 HydrophobicContact CB-CG 3.83Å; P51-Y252 HydrophobicContact CG-CG 4.42Å; T55-Y252 HydrophobicContact CG2-CD2 4.2Å; T121-Y252 HydrophobicContact CG2-CD1 3.88Å; T121-Y252 HydrophobicContact CG2-CE1 3.93Å; V125-Y252 HydrophobicContact CG2-CD1 3.93Å; V125-Y252 HydrophobicContact CG2-CG 3.92Å; Q156-Y252 PolarHBondContact NE2-OH 3.31Å; Q156-Y252 PolarHBondContact OE1-OH 2.96Å; F159-Y252 WeakPolarHBondContact CB-OH 3.44Å; F159-Y252 WeakPolarHBondContact CD1-OH 3.27Å; F159-Y252 HydrophobicContact CD2-CE1 4.4Å; F159-Y252 HydrophobicContact CE2-CE1 4.42Å; F159-Y252 VanDerWaalsContact CG-OH 3.26Å; F159-Y252 WeakPolarHBondContact CG-OH 3.16Å; I248-Y252 PolarHBondContact O-N 3.33Å; C249-Y252 WeakPolarHBondContact O-CB 3.49Å; C249-Y252 PolarHBondContact O-N 3.08Å; S250-Y252 PolarHBondContact O-N 2.92Å; Y252-L254 VanDerWaalsContact C-N 3.32Å; Y252-L254 PolarHBondContact O-N 3.46Å; Y252-C255 PolarHBondContact O-N 3.29Å; Y252-A256 PolarHBondContact O-N 2.87Å
253	V	91.1	Very high	89.3	Confident	54 Å²	54	41.6 Å²	41.6	33%	0.327	25%	0.246	S	C	.	.	H	α-helix	trans	-60.5	-43.7	-179.6	174.9	0	0	0	0	110.7	T121 V125 C249 S250 C255 A256 I257	T121-V253 HydrophobicContact CG2-CG2 4.42Å; V125-V253 HydrophobicContact CG1-CG2 4.29Å; V125-V253 HydrophobicContact CG2-CG2 3.82Å; C249-V253 WeakPolarHBondContact O-CG2 3.28Å; C249-V253 PolarHBondContact O-N 3.45Å; C249-V253 VanDerWaalsContact O-N 3.07Å; S250-V253 PolarHBondContact O-N 2.9Å; V253-C255 PolarHBondContact O-N 3.22Å; V253-A256 PolarHBondContact O-N 3Å; V253-I257 HydrophobicContact CG1-CD1 3.78Å; V253-I257 HydrophobicContact CG1-CG1 4.39Å; V253-I257 VanDerWaalsContact O-CG1 3.29Å; V253-I257 WeakPolarHBondContact O-CG1 3.3Å; V253-I257 PolarHBondContact O-N 3.16Å
254	L	91.7	Very high	88.5	Confident	106 Å²	106	46.8 Å²	46.8	56%	0.555	26%	0.26	S	S	*	.	H	α-helix	trans	-59.2	-46.2	177	-174.4	70.2	0	0	0	111.7	S250 M251 Y252 A256 I257 V258	S250-L254 WeakPolarHBondContact O-CB 3.34Å; S250-L254 PolarHBondContact O-N 3.41Å; M251-L254 PolarHBondContact O-N 2.67Å; Y252-L254 VanDerWaalsContact C-N 3.32Å; Y252-L254 PolarHBondContact O-N 3.46Å; L254-A256 VanDerWaalsContact C-N 3.34Å; L254-A256 PolarHBondContact O-N 3.35Å; L254-I257 PolarHBondContact O-N 3.44Å; L254-V258 WeakPolarHBondContact O-CG2 3.47Å; L254-V258 PolarHBondContact O-N 3.02Å
255	C	90.5	Very high	87.6	Confident	10 Å²	10	47.5 Å²	47.5	7%	0.068	26%	0.263	C	S	.	.	H	α-helix	trans	-63.5	-40.1	178.4	-65.1	0	0	0	0	111.9	I47 P51 M251 Y252 V253 V258 L259	I47-C255 HydrophobicContact CG2-CB 3.82Å; P51-C255 HydrophobicContact CG-CB 3.49Å; P51-C255 VanDerWaalsContact CG-CB 3.49Å; M251-C255 PolarHBondContact O-N 3.37Å; M251-C255 PolarHBondContact O-SG 3.04Å; Y252-C255 PolarHBondContact O-N 3.29Å; V253-C255 PolarHBondContact O-N 3.22Å; C255-V258 PolarHBondContact O-N 3.47Å; C255-L259 WeakPolarHBondContact O-CB 3.43Å; C255-L259 PolarHBondContact O-N 3.42Å
256	A	87.8	Confident	86.5	Confident	2 Å²	2	53.2 Å²	53.2	2%	0.017	29%	0.29	C	S	.	.	H	α-helix	trans	-64.9	-40.3	176.9	0	0	0	0	0	112.2	T121 F159 Y252 V253 L254 L259 F260	T121-A256 HydrophobicContact CG2-CB 3.88Å; F159-A256 HydrophobicContact CE2-CB 4.13Å; Y252-A256 PolarHBondContact O-N 2.87Å; V253-A256 PolarHBondContact O-N 3Å; L254-A256 VanDerWaalsContact C-N 3.34Å; L254-A256 PolarHBondContact O-N 3.35Å; A256-L259 PolarHBondContact O-N 3.47Å; A256-F260 WeakPolarHBondContact O-CB 3.47Å; A256-F260 PolarHBondContact O-N 3.16Å
257	I	87.8	Confident	85	Confident	89 Å²	89	57.6 Å²	57.6	46%	0.456	30%	0.302	S	S	.	.	H	α-helix	trans	-63.7	-46.5	175.2	-68.4	166.5	0	0	0	110.5	V253 L254 L259 F260 S261	V253-I257 HydrophobicContact CG1-CD1 3.78Å; V253-I257 HydrophobicContact CG1-CG1 4.39Å; V253-I257 VanDerWaalsContact O-CG1 3.29Å; V253-I257 WeakPolarHBondContact O-CG1 3.3Å; V253-I257 PolarHBondContact O-N 3.16Å; L254-I257 PolarHBondContact O-N 3.44Å; I257-L259 VanDerWaalsContact C-N 3.34Å; I257-L259 PolarHBondContact O-N 3.26Å; I257-F260 PolarHBondContact O-N 3.06Å; I257-S261 WeakPolarHBondContact O-CB 3.41Å; I257-S261 PolarHBondContact O-N 3.39Å; I257-S261 PolarHBondContact O-OG 2.98Å
258	V	88.8	Confident	83.1	Confident	41 Å²	41	57.3 Å²	57.3	25%	0.248	31%	0.306	C	S	.	.	H	α-helix	trans	-61.3	-43	179.1	171.2	0	0	0	0	111.5	C44 I47 L254 C255 G262	C44-V258 HydrophobicContact CB-CG1 4.13Å; I47-V258 HydrophobicContact CB-CG1 4.21Å; I47-V258 HydrophobicContact CD1-CG1 3.83Å; I47-V258 HydrophobicContact CG2-CB 4.11Å; I47-V258 HydrophobicContact CG2-CG1 4.02Å; L254-V258 WeakPolarHBondContact O-CG2 3.47Å; L254-V258 PolarHBondContact O-N 3.02Å; C255-V258 PolarHBondContact O-N 3.47Å; V258-G262 PolarHBondContact O-N 2.66Å
259	L	85.7	Confident	80.8	Confident	4 Å²	4	63.8 Å²	63.8	2%	0.021	35%	0.346	C	S	.	.	H	α-helix	trans	-60.7	-47.8	175.9	-179.6	67.4	0	0	0	111.1	Y45 F159 Y163 L166 C255 A256 I257 V263	Y45-L259 HydrophobicContact CD2-CD1 4.32Å; F159-L259 HydrophobicContact CE2-CD2 4.44Å; F159-L259 HydrophobicContact CZ-CD2 4.16Å; Y163-L259 HydrophobicContact CD2-CD1 4.06Å; Y163-L259 HydrophobicContact CD2-CD2 3.73Å; Y163-L259 HydrophobicContact CE2-CD1 3.97Å; Y163-L259 HydrophobicContact CE2-CD2 4.33Å; L166-L259 HydrophobicContact CD2-CD1 4.24Å; C255-L259 WeakPolarHBondContact O-CB 3.43Å; C255-L259 PolarHBondContact O-N 3.42Å; A256-L259 PolarHBondContact O-N 3.47Å; I257-L259 VanDerWaalsContact C-N 3.34Å; I257-L259 PolarHBondContact O-N 3.26Å; L259-V263 HydrophobicContact CD1-CB 4.42Å; L259-V263 HydrophobicContact CD1-CG2 3.97Å; L259-V263 WeakPolarHBondContact O-CB 3.46Å; L259-V263 PolarHBondContact O-N 3.15Å; L259-V263 VanDerWaalsContact O-N 3.13Å
260	F	81.6	Confident	78.4	Confident	93 Å²	93	66.1 Å²	66.1	41%	0.408	37%	0.372	S	S	.	.	H	α-helix	trans	-63.2	-44.2	-179.3	-177.1	-112.6	0	0	0	112.9	I117 A256 I257	I117-F260 HydrophobicContact CB-CB 4.47Å; I117-F260 HydrophobicContact CB-CD2 4.19Å; I117-F260 HydrophobicContact CB-CG 4.42Å; I117-F260 HydrophobicContact CD1-CB 3.73Å; I117-F260 HydrophobicContact CD1-CD2 3.46Å; I117-F260 VanDerWaalsContact CD1-CD2 3.46Å; I117-F260 HydrophobicContact CD1-CE2 4.46Å; I117-F260 HydrophobicContact CD1-CG 3.99Å; I117-F260 HydrophobicContact CG1-CB 3.97Å; I117-F260 HydrophobicContact CG1-CD2 4.17Å; I117-F260 HydrophobicContact CG1-CG 4.36Å; I117-F260 HydrophobicContact CG2-CB 3.88Å; I117-F260 HydrophobicContact CG2-CD1 4.31Å; I117-F260 HydrophobicContact CG2-CD2 3.99Å; I117-F260 HydrophobicContact CG2-CG 3.79Å; A256-F260 WeakPolarHBondContact O-CB 3.47Å; A256-F260 PolarHBondContact O-N 3.16Å; I257-F260 PolarHBondContact O-N 3.06Å
261	S	81	Confident	76.1	Confident	94 Å²	94	70 Å²	70	66%	0.657	38%	0.384	S	S	*	.	H	α-helix	trans	-77.2	-29.9	-177.8	-61.4	0	0	0	0	113	I257	I257-S261 WeakPolarHBondContact O-CB 3.41Å; I257-S261 PolarHBondContact O-N 3.39Å; I257-S261 PolarHBondContact O-OG 2.98Å
262	G	77.3	Confident	73.8	Confident	20 Å²	20	79.8 Å²	79.8	21%	0.206	42%	0.418	C	S	.	.	H	α-helix	trans	-94.8	-20.3	-171.9	0	0	0	0	0	115.5	V258	V258-G262 PolarHBondContact O-N 2.66Å
263	V	80.5	Confident	71.9	Confident	12 Å²	12	82.5 Å²	82.5	7%	0.073	44%	0.438	C	S	.	.			trans	-119.8	129.1	-173.4	-176	0	0	0	0	110.6	C44 M112 L166 I170 L259	C44-V263 HydrophobicContact CB-CG2 4.26Å; M112-V263 HydrophobicContact CE-CB 3.93Å; M112-V263 HydrophobicContact CE-CG1 4.31Å; M112-V263 WeakPolarHBondContact CE-O 3.14Å; L166-V263 HydrophobicContact CD2-CG1 3.93Å; I170-V263 HydrophobicContact CD1-CG1 3.68Å; I170-V263 HydrophobicContact CG1-CG1 3.73Å; L259-V263 HydrophobicContact CD1-CB 4.42Å; L259-V263 HydrophobicContact CD1-CG2 3.97Å; L259-V263 WeakPolarHBondContact O-CB 3.46Å; L259-V263 PolarHBondContact O-N 3.15Å; L259-V263 VanDerWaalsContact O-N 3.13Å
264	R	75.2	Confident	70	Confident	206 Å²	206	88.8 Å²	88.8	78%	0.777	46%	0.461	S	S	*	.			trans	-119.5	130.5	174.3	-165.5	172.6	-176.4	173.3	0.5	109.7	H266	R264-H266 PolarHBondContact O-ND1 3.5Å
265	E	73.8	Confident	68.3	Low	16 Å²	16	89.9 Å²	89.9	8%	0.075	48%	0.475	C	S	.	.			trans	-70.1	140.6	176.8	-75.4	-176.2	-158.1	0	0	111.8	G109 R110 M111 M112 L166	G109-E265 WeakPolarHBondContact CA-OE2 3.28Å; R110-E265 PolarHBondContact N-OE2 2.59Å; M111-E265 WeakPolarHBondContact CA-OE1 3.18Å; M111-E265 WeakPolarHBondContact CB-OE1 3.42Å; M111-E265 PolarHBondContact N-OE1 3.25Å; M111-E265 VanDerWaalsContact N-OE1 3.1Å; M111-E265 PolarHBondContact N-OE2 3.25Å; M111-E265 VanDerWaalsContact N-OE2 3.17Å; M112-E265 WeakPolarHBondContact CA-OE1 3.35Å; M112-E265 VanDerWaalsContact CB-OE1 3.23Å; M112-E265 WeakPolarHBondContact CB-OE1 3.24Å; M112-E265 HydrophobicContact CG-CG 3.92Å; M112-E265 WeakPolarHBondContact CG-OE1 3.26Å; M112-E265 PolarHBondContact N-OE1 3.34Å; L166-E265 HydrophobicContact CD1-CG 3.45Å; L166-E265 VanDerWaalsContact CD1-CG 3.45Å; L166-E265 VanDerWaalsContact CD1-OE1 3.3Å; L166-E265 WeakPolarHBondContact CD1-OE1 3.07Å
266	H	68.8	Low	67	Low	120 Å²	120	92.6 Å²	92.6	56%	0.556	49%	0.487	S	S	*	.			trans	-115	142	168.5	-65.7	77.1	0	0	0	108.7	F169 R264 A268	F169-H266 PolarHBondContact O-N 3.44Å; R264-H266 PolarHBondContact O-ND1 3.5Å; H266-A268 PolarHBondContact O-N 3.03Å; H266-A268 VanDerWaalsContact O-N 3.08Å
267	E	62.7	Low	66.2	Low	138 Å²	138	96.7 Å²	96.7	65%	0.645	51%	0.513	S	S	*	.			trans	-66	112.1	174.3	-168.9	168.1	-168	0	0	108.7	W105 T269	W105-E267 HydrophobicContact CH2-CB 3.75Å; W105-E267 HydrophobicContact CH2-CG 4.1Å; W105-E267 HydrophobicContact CZ2-CB 4.03Å; W105-E267 HydrophobicContact CZ2-CG 3.84Å; W105-E267 HydrophobicContact CZ3-CB 4.16Å; E267-T269 PolarHBondContact O-N 3.14Å
268	A	56.1	Low	65.2	Low	50 Å²	50	97.7 Å²	97.7	41%	0.413	52%	0.515	S	S	.	.			trans	-67.8	102.3	174.5	0	0	0	0	0	108.3	F169 H266 G270	F169-A268 HydrophobicContact CD1-CB 4Å; F169-A268 HydrophobicContact CE1-CB 4.25Å; H266-A268 PolarHBondContact O-N 3.03Å; H266-A268 VanDerWaalsContact O-N 3.08Å; A268-G270 PolarHBondContact O-N 3.17Å; A268-G270 VanDerWaalsContact O-N 3.14Å
269	T	45.3	Very low	64.5	Low	139 Å²	139	102.3 Å²	102.3	85%	0.853	54%	0.537	S	S	*	.			trans	-72.8	93.9	165.9	44.9	0	0	0	0	108.3	E267	E267-T269 PolarHBondContact O-N 3.14Å
270	G	44.2	Very low	64	Low	60 Å²	60	108.5 Å²	108.5	62%	0.619	56%	0.564	S	S	*	*	S	Bend	trans	160.5	119.4	172.6	0	0	0	0	0	115.3	A268	A268-G270 PolarHBondContact O-N 3.17Å; A268-G270 VanDerWaalsContact O-N 3.14Å
271	I	43.4	Very low	63.6	Low	163 Å²	163	104.2 Å²	104.2	84%	0.836	55%	0.546	S	S	*	.			trans	61.7	83.8	162	-40.6	177.2	0	0	0	115.8	S273	I271-S273 PolarHBondContact O-N 3.15Å
272	R	44.7	Very low	63.3	Low	253 Å²	253	101.6 Å²	101.6	96%	0.955	52%	0.524	S	S	*	.			trans	-69.8	100.7	155.1	-87.4	-179.5	173.2	174.1	-0.7	108.5
273	S	51.3	Low	63.5	Low	62 Å²	62	108.9 Å²	108.9	43%	0.434	55%	0.55	S	S	.	*	P	Polyproline II helix	trans	-63.4	139.1	162.1	57.7	0	0	0	0	109.1	I271	I271-S273 PolarHBondContact O-N 3.15Å
274	K	51.3	Low	63.4	Low	187 Å²	187	111.2 Å²	111.2	81%	0.813	56%	0.561	S	S	*	*	P	Polyproline II helix	trans	-59.8	129	176.3	-77.2	178.9	179.7	171.8	0	108.4	M276	K274-M276 PolarHBondContact O-N 3.43Å; K274-M276 VanDerWaalsContact O-N 3.12Å
275	P	55.9	Low	63.6	Low	129 Å²	129	101.5 Å²	101.5	84%	0.838	53%	0.525	S	S	*	.	P	Polyproline II helix	trans	-64.8	117.8	-179.8	24.5	-31.6	0	0	0	109.7
276	M	63.5	Low	63.8	Low	67 Å²	67	105.4 Å²	105.4	33%	0.33	54%	0.544	S	S	.	.	P	Polyproline II helix	trans	-88.5	151.6	171.7	-88.9	-143.5	-80.2	0	0	111.7	K274 F278 K280 M284 H420	K274-M276 PolarHBondContact O-N 3.43Å; K274-M276 VanDerWaalsContact O-N 3.12Å; M276-F278 PolarHBondContact O-N 3.05Å; M276-K280 HydrophobicContact SD-CD 3.98Å; M276-K280 HydrophobicContact SD-CG 4.43Å; M276-M284 HydrophobicContact CE-SD 4.39Å; M276-H420 WeakPolarHBondContact CE-NE2 3.41Å
277	P	70.8	Confident	64.4	Low	87 Å²	87	102.7 Å²	102.7	57%	0.565	55%	0.548	S	S	*	.	P	Polyproline II helix	trans	-63.8	133.8	171.6	-7.3	18.7	0	0	0	110.7	L279 K280 G281	P277-L279 PolarHBondContact O-N 3.01Å; P277-K280 HydrophobicContact CB-CB 4.46Å; P277-K280 HydrophobicContact CG-CB 4.43Å; P277-K280 WeakPolarHBondContact O-CB 3.23Å; P277-K280 PolarHBondContact O-N 3.14Å; P277-G281 PolarHBondContact O-N 2.7Å
278	F	68.4	Low	65.6	Low	111 Å²	111	97.1 Å²	97.1	49%	0.487	52%	0.522	S	S	.	.	H	α-helix	trans	-50.1	-50.2	-176.7	-178.7	-112.2	0	0	0	113.1	P94 M276 K280 G281 I282 F427	P94-F278 HydrophobicContact CB-CZ 4.42Å; M276-F278 PolarHBondContact O-N 3.05Å; F278-K280 VanDerWaalsContact C-N 3.27Å; F278-K280 PolarHBondContact O-N 3.4Å; F278-G281 WeakPolarHBondContact O-CA 3.48Å; F278-G281 PolarHBondContact O-N 3.32Å; F278-I282 HydrophobicContact CD1-CD1 3.87Å; F278-I282 HydrophobicContact CD1-CG1 4.36Å; F278-I282 HydrophobicContact CE1-CD1 3.5Å; F278-I282 HydrophobicContact CE1-CG1 4.28Å; F278-I282 HydrophobicContact CZ-CD1 3.94Å; F278-I282 HydrophobicContact CZ-CG1 4.47Å; F278-I282 VanDerWaalsContact O-CG1 3.23Å; F278-I282 WeakPolarHBondContact O-CG1 3.31Å; F278-I282 PolarHBondContact O-N 2.95Å; F278-F427 HydrophobicContact CE2-CE2 4.45Å; F278-F427 HydrophobicContact CE2-CZ 4.08Å; F278-F427 AromaticContact CZ-CZ 3.84Å; F278-F427 HydrophobicContact CZ-CZ 3.84Å
279	L	72.4	Confident	67.1	Low	138 Å²	138	96.5 Å²	96.5	72%	0.723	52%	0.521	S	S	*	.	H	α-helix	trans	-58.4	-35.3	179.6	-90.7	86.9	0	0	0	113.6	P277 I282 K283	P277-L279 PolarHBondContact O-N 3.01Å; L279-I282 PolarHBondContact O-N 3.27Å; L279-K283 PolarHBondContact O-N 2.96Å; L279-K283 VanDerWaalsContact O-N 3.15Å
280	K	76.4	Confident	69.2	Low	133 Å²	133	90.8 Å²	90.8	58%	0.578	49%	0.486	S	S	*	.	H	α-helix	trans	-69.5	-39	178.5	-168.8	178.7	177.8	-173.4	0	110.5	M276 P277 F278 K283 M284	M276-K280 HydrophobicContact SD-CD 3.98Å; M276-K280 HydrophobicContact SD-CG 4.43Å; P277-K280 HydrophobicContact CB-CB 4.46Å; P277-K280 HydrophobicContact CG-CB 4.43Å; P277-K280 WeakPolarHBondContact O-CB 3.23Å; P277-K280 PolarHBondContact O-N 3.14Å; F278-K280 VanDerWaalsContact C-N 3.27Å; F278-K280 PolarHBondContact O-N 3.4Å; K280-K283 PolarHBondContact O-N 3.44Å; K280-M284 WeakPolarHBondContact O-CB 2.98Å; K280-M284 PolarHBondContact O-N 3.33Å; K280-M284 VanDerWaalsContact O-N 3.11Å
281	G	72.6	Confident	71.4	Confident	3 Å²	3	88 Å²	88	3%	0.031	46%	0.457	C	S	.	.	H	α-helix	trans	-60.2	-46.3	172.6	0	0	0	0	0	112.5	P277 F278 K283 M284 V285	P277-G281 PolarHBondContact O-N 2.7Å; F278-G281 WeakPolarHBondContact O-CA 3.48Å; F278-G281 PolarHBondContact O-N 3.32Å; G281-K283 PolarHBondContact O-N 3.09Å; G281-M284 PolarHBondContact O-N 2.95Å; G281-V285 WeakPolarHBondContact O-CB 3.38Å; G281-V285 WeakPolarHBondContact O-CG2 3.28Å; G281-V285 PolarHBondContact O-N 3.02Å
282	I	74.6	Confident	73.6	Confident	40 Å²	40	81.8 Å²	81.8	21%	0.205	43%	0.43	C	S	.	.	H	α-helix	trans	-57.6	-50.5	177.6	-41.4	-164.2	0	0	0	111	F278 L279 M284 V285 M286 F427	F278-I282 HydrophobicContact CD1-CD1 3.87Å; F278-I282 HydrophobicContact CD1-CG1 4.36Å; F278-I282 HydrophobicContact CE1-CD1 3.5Å; F278-I282 HydrophobicContact CE1-CG1 4.28Å; F278-I282 HydrophobicContact CZ-CD1 3.94Å; F278-I282 HydrophobicContact CZ-CG1 4.47Å; F278-I282 VanDerWaalsContact O-CG1 3.23Å; F278-I282 WeakPolarHBondContact O-CG1 3.31Å; F278-I282 PolarHBondContact O-N 2.95Å; L279-I282 PolarHBondContact O-N 3.27Å; I282-M284 VanDerWaalsContact C-N 3.26Å; I282-M284 PolarHBondContact O-N 3.32Å; I282-V285 PolarHBondContact O-N 3.48Å; I282-M286 HydrophobicContact CG2-CG 4.16Å; I282-M286 HydrophobicContact CG2-SD 4.26Å; I282-M286 WeakPolarHBondContact O-CB 3.42Å; I282-M286 PolarHBondContact O-N 2.82Å; I282-F427 HydrophobicContact CB-CE1 4.49Å; I282-F427 HydrophobicContact CB-CE2 4.19Å; I282-F427 HydrophobicContact CB-CZ 3.87Å; I282-F427 HydrophobicContact CD1-CE1 3.98Å; I282-F427 HydrophobicContact CD1-CE2 4.44Å; I282-F427 HydrophobicContact CD1-CZ 3.46Å; I282-F427 VanDerWaalsContact CD1-CZ 3.46Å; I282-F427 HydrophobicContact CG1-CE1 4.15Å; I282-F427 HydrophobicContact CG1-CE2 3.81Å; I282-F427 HydrophobicContact CG1-CZ 3.28Å; I282-F427 HydrophobicContact CG2-CE1 3.86Å; I282-F427 HydrophobicContact CG2-CE2 4.28Å; I282-F427 HydrophobicContact CG2-CZ 3.74Å
283	K	80.9	Confident	75.8	Confident	173 Å²	173	73.7 Å²	73.7	75%	0.752	40%	0.401	S	S	*	.	H	α-helix	trans	-62.4	-37.7	-175.9	-172.4	175.6	-179.4	177.6	0	111.4	L279 K280 G281 G287	L279-K283 PolarHBondContact O-N 2.96Å; L279-K283 VanDerWaalsContact O-N 3.15Å; K280-K283 PolarHBondContact O-N 3.44Å; G281-K283 PolarHBondContact O-N 3.09Å; K283-G287 PolarHBondContact O-N 3.37Å
284	M	78.8	Confident	77.7	Confident	60 Å²	60	70.9 Å²	70.9	30%	0.296	38%	0.381	S	S	.	.	H	α-helix	trans	-67.9	-46.5	177.3	-167.8	177.7	-170.4	0	0	111.7	M276 K280 G281 I282 G287 Y288 F410	M276-M284 HydrophobicContact CE-SD 4.39Å; K280-M284 WeakPolarHBondContact O-CB 2.98Å; K280-M284 PolarHBondContact O-N 3.33Å; K280-M284 VanDerWaalsContact O-N 3.11Å; G281-M284 PolarHBondContact O-N 2.95Å; I282-M284 VanDerWaalsContact C-N 3.26Å; I282-M284 PolarHBondContact O-N 3.32Å; M284-G287 PolarHBondContact O-N 2.77Å; M284-Y288 PolarHBondContact O-N 3.35Å; M284-F410 HydrophobicContact CE-CE1 4.32Å; M284-F410 HydrophobicContact CE-CE2 4.22Å; M284-F410 HydrophobicContact CE-CZ 3.45Å; M284-F410 VanDerWaalsContact CE-CZ 3.45Å; M284-F410 HydrophobicContact CG-CE2 4.34Å; M284-F410 HydrophobicContact CG-CZ 4Å; M284-F410 HydrophobicContact SD-CZ 3.99Å
285	V	78.9	Confident	79.6	Confident	3 Å²	3	62.3 Å²	62.3	2%	0.018	34%	0.344	C	S	.	.	H	α-helix	trans	-68.8	-46.8	-178.4	169.7	0	0	0	0	111.7	G281 I282 G287 Y288 Y291 I423 F424	G281-V285 WeakPolarHBondContact O-CB 3.38Å; G281-V285 WeakPolarHBondContact O-CG2 3.28Å; G281-V285 PolarHBondContact O-N 3.02Å; I282-V285 PolarHBondContact O-N 3.48Å; V285-G287 VanDerWaalsContact C-N 3.3Å; V285-G287 PolarHBondContact O-N 3.31Å; V285-Y288 WeakPolarHBondContact O-CB 3.28Å; V285-Y288 PolarHBondContact O-N 3.48Å; V285-Y288 VanDerWaalsContact O-N 3.16Å; V285-Y291 HydrophobicContact CG1-CD1 3.52Å; V285-Y291 HydrophobicContact CG1-CE1 3.17Å; V285-Y291 HydrophobicContact CG1-CE2 4.42Å; V285-Y291 HydrophobicContact CG1-CG 4.28Å; V285-Y291 WeakPolarHBondContact O-CD1 3.3Å; V285-I423 HydrophobicContact CG2-CB 4.42Å; V285-I423 HydrophobicContact CG2-CG2 3.84Å; V285-F424 HydrophobicContact CB-CE1 4.29Å; V285-F424 HydrophobicContact CB-CZ 4.46Å; V285-F424 HydrophobicContact CG1-CD1 3.72Å; V285-F424 HydrophobicContact CG1-CE1 3.8Å; V285-F424 HydrophobicContact CG1-CG 4.26Å; V285-F424 HydrophobicContact CG1-CZ 4.41Å; V285-F424 HydrophobicContact CG2-CD1 4.29Å; V285-F424 HydrophobicContact CG2-CD2 4.12Å; V285-F424 HydrophobicContact CG2-CE1 4.03Å; V285-F424 HydrophobicContact CG2-CE2 3.84Å; V285-F424 HydrophobicContact CG2-CG 4.33Å; V285-F424 HydrophobicContact CG2-CZ 3.79Å
286	M	78.6	Confident	81.2	Confident	97 Å²	97	60.1 Å²	60.1	48%	0.478	32%	0.324	S	S	.	.	H	α-helix	trans	-71.1	-24.2	177.1	-72.5	-154.9	71.7	0	0	113.4	I282 Y288 F431	I282-M286 HydrophobicContact CG2-CG 4.16Å; I282-M286 HydrophobicContact CG2-SD 4.26Å; I282-M286 WeakPolarHBondContact O-CB 3.42Å; I282-M286 PolarHBondContact O-N 2.82Å; M286-Y288 PolarHBondContact O-N 2.78Å; M286-F431 HydrophobicContact CE-CZ 4.27Å; M286-F431 HydrophobicContact SD-CE2 4.46Å; M286-F431 HydrophobicContact SD-CZ 4.21Å
287	G	81.2	Confident	82.6	Confident	63 Å²	63	57 Å²	57	65%	0.649	31%	0.309	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.5	-16.2	172	0	0	0	0	0	113.2	K283 M284 V285 G289	K283-G287 PolarHBondContact O-N 3.37Å; M284-G287 PolarHBondContact O-N 2.77Å; V285-G287 VanDerWaalsContact C-N 3.3Å; V285-G287 PolarHBondContact O-N 3.31Å; G287-G289 PolarHBondContact O-N 2.87Å
288	Y	87.6	Confident	83.5	Confident	21 Å²	21	53 Å²	53	8%	0.082	28%	0.282	C	S	.	.			trans	-80.1	103.8	-180	-164.5	-121.1	0	0	0	111.4	M284 V285 M286 P290 Y291 A292 V406 D409 F410 Q413	M284-Y288 PolarHBondContact O-N 3.35Å; V285-Y288 WeakPolarHBondContact O-CB 3.28Å; V285-Y288 PolarHBondContact O-N 3.48Å; V285-Y288 VanDerWaalsContact O-N 3.16Å; M286-Y288 PolarHBondContact O-N 2.78Å; Y288-P290 HydrophobicContact CD1-CB 4.25Å; Y288-P290 HydrophobicContact CD1-CG 4.3Å; Y288-P290 HydrophobicContact CE1-CB 3.75Å; Y288-P290 HydrophobicContact CE1-CG 3.71Å; Y288-P290 HydrophobicContact CE2-CG 4.27Å; Y288-Y291 WeakPolarHBondContact O-CB 3.39Å; Y288-Y291 PolarHBondContact O-N 3.36Å; Y288-Y291 VanDerWaalsContact O-N 3.08Å; Y288-A292 PolarHBondContact O-N 3.17Å; Y288-V406 HydrophobicContact CD1-CG1 3.96Å; Y288-V406 HydrophobicContact CE1-CG1 3.87Å; Y288-D409 PolarHBondContact OH-OD2 3.3Å; Y288-F410 HydrophobicContact CD1-CB 4.43Å; Y288-F410 HydrophobicContact CD1-CD2 4.21Å; Y288-F410 AromaticContact CD2-CD2 3.91Å; Y288-F410 HydrophobicContact CD2-CD2 3.91Å; Y288-F410 HydrophobicContact CE1-CB 4.13Å; Y288-F410 HydrophobicContact CE1-CD2 4.49Å; Y288-F410 HydrophobicContact CE2-CD2 4.21Å; Y288-F410 AromaticContact CG-CD2 3.93Å; Y288-F410 HydrophobicContact CG-CD2 3.93Å; Y288-Q413 PolarHBondContact OH-NE2 2.99Å; Y288-Q413 PolarHBondContact OH-OE1 3.39Å
289	G	87.7	Confident	84.7	Confident	38 Å²	38	48.9 Å²	48.9	39%	0.392	27%	0.266	S	S	.	.	H	α-helix	trans	-51.4	-47.4	-175	0	0	0	0	0	115.4	G287 Y291 A292 K293	G287-G289 PolarHBondContact O-N 2.87Å; G289-Y291 VanDerWaalsContact C-N 3.34Å; G289-Y291 PolarHBondContact O-N 2.91Å; G289-A292 PolarHBondContact O-N 3.42Å; G289-K293 WeakPolarHBondContact O-CG 3.45Å; G289-K293 PolarHBondContact O-N 3.29Å; G289-K293 VanDerWaalsContact O-N 3.11Å
290	P	89.6	Confident	85.6	Confident	19 Å²	19	44.6 Å²	44.6	12%	0.123	24%	0.241	C	C	.	.	H	α-helix	trans	-61.4	-39.3	177.1	-24.7	35	0	0	0	113.3	Y288 L294 P490 I491	Y288-P290 HydrophobicContact CD1-CB 4.25Å; Y288-P290 HydrophobicContact CD1-CG 4.3Å; Y288-P290 HydrophobicContact CE1-CB 3.75Å; Y288-P290 HydrophobicContact CE1-CG 3.71Å; Y288-P290 HydrophobicContact CE2-CG 4.27Å; P290-L294 WeakPolarHBondContact O-CB 3.3Å; P290-L294 PolarHBondContact O-N 3.18Å; P290-L294 VanDerWaalsContact O-N 3.08Å; P290-P490 HydrophobicContact CB-CG 3.98Å; P290-P490 HydrophobicContact CG-CG 3.91Å; P290-I491 HydrophobicContact CB-CD1 4.02Å
291	Y	89.8	Confident	86.3	Confident	2 Å²	2	38.5 Å²	38.5	1%	0.008	22%	0.215	C	C	.	.	H	α-helix	trans	-66.1	-49.6	176.2	177	-105	0	0	0	111.9	V285 Y288 G289 K293 L294 V295 L403 V406 F424 F427 Y428	V285-Y291 HydrophobicContact CG1-CD1 3.52Å; V285-Y291 HydrophobicContact CG1-CE1 3.17Å; V285-Y291 HydrophobicContact CG1-CE2 4.42Å; V285-Y291 HydrophobicContact CG1-CG 4.28Å; V285-Y291 WeakPolarHBondContact O-CD1 3.3Å; Y288-Y291 WeakPolarHBondContact O-CB 3.39Å; Y288-Y291 PolarHBondContact O-N 3.36Å; Y288-Y291 VanDerWaalsContact O-N 3.08Å; G289-Y291 VanDerWaalsContact C-N 3.34Å; G289-Y291 PolarHBondContact O-N 2.91Å; Y291-K293 VanDerWaalsContact C-N 3.27Å; Y291-K293 PolarHBondContact O-N 3.09Å; Y291-L294 PolarHBondContact O-N 3.36Å; Y291-L294 VanDerWaalsContact O-N 3.08Å; Y291-V295 HydrophobicContact CD1-CG2 4.04Å; Y291-V295 HydrophobicContact CD2-CG2 3.82Å; Y291-V295 HydrophobicContact CE1-CG2 3.61Å; Y291-V295 HydrophobicContact CE2-CG2 3.41Å; Y291-V295 VanDerWaalsContact CE2-CG2 3.41Å; Y291-V295 HydrophobicContact CG-CG2 4.15Å; Y291-V295 WeakPolarHBondContact O-CG2 3.5Å; Y291-V295 PolarHBondContact O-N 3.08Å; Y291-L403 HydrophobicContact CD2-CD1 4.25Å; Y291-L403 HydrophobicContact CE2-CD1 3.78Å; Y291-V406 HydrophobicContact CD2-CG1 4.08Å; Y291-V406 HydrophobicContact CG-CG1 4.38Å; Y291-F424 HydrophobicContact CD1-CD1 4.38Å; Y291-F424 AromaticContact CD2-CD1 3.45Å; Y291-F424 HydrophobicContact CD2-CD1 3.45Å; Y291-F424 VanDerWaalsContact CD2-CD1 3.45Å; Y291-F424 HydrophobicContact CD2-CE1 4.01Å; Y291-F424 HydrophobicContact CE1-CD1 4.49Å; Y291-F424 HydrophobicContact CE2-CB 4.11Å; Y291-F424 AromaticContact CE2-CD1 3.54Å; Y291-F424 HydrophobicContact CE2-CD1 3.54Å; Y291-F424 HydrophobicContact CE2-CE1 4.46Å; Y291-F424 HydrophobicContact CE2-CG 4.31Å; Y291-F424 AromaticContact CG-CD1 3.85Å; Y291-F424 HydrophobicContact CG-CD1 3.85Å; Y291-F424 AromaticContact CG-CE1 3.98Å; Y291-F424 HydrophobicContact CG-CE1 3.98Å; Y291-F424 PolarHBondContact OH-O 3.08Å; Y291-F427 WeakPolarHBondContact OH-CB 3.48Å; Y291-Y428 PolarHBondContact OH-N 2.81Å
292	A	90.1	Very high	87.2	Confident	32 Å²	32	39.4 Å²	39.4	26%	0.264	22%	0.221	S	C	.	.	H	α-helix	trans	-56.9	-42.8	179.8	0	0	0	0	0	111.5	Y288 G289 M296	Y288-A292 PolarHBondContact O-N 3.17Å; G289-A292 PolarHBondContact O-N 3.42Å; A292-M296 VanDerWaalsContact O-CB 3.3Å; A292-M296 WeakPolarHBondContact O-CB 3.17Å; A292-M296 WeakPolarHBondContact O-CG 3.49Å; A292-M296 PolarHBondContact O-N 3.31Å
293	K	91.4	Very high	88	Confident	83 Å²	83	38.7 Å²	38.7	36%	0.361	22%	0.217	S	C	.	.	H	α-helix	trans	-63.2	-43.8	175.2	-71.1	174.7	175.3	-175.8	0	112.7	G289 Y291 G297 I485 T488	G289-K293 WeakPolarHBondContact O-CG 3.45Å; G289-K293 PolarHBondContact O-N 3.29Å; G289-K293 VanDerWaalsContact O-N 3.11Å; Y291-K293 VanDerWaalsContact C-N 3.27Å; Y291-K293 PolarHBondContact O-N 3.09Å; K293-G297 PolarHBondContact O-N 3.2Å; K293-I485 WeakPolarHBondContact O-CG2 3.4Å; K293-T488 PolarHBondContact NZ-O 3.28Å; K293-T488 VanDerWaalsContact NZ-O 3.07Å
294	L	90.8	Very high	88.6	Confident	2 Å²	2	30.5 Å²	30.5	1%	0.01	18%	0.181	C	C	.	.	H	α-helix	trans	-62.9	-50.2	178.7	-170.1	74.5	0	0	0	111.2	P290 Y291 G297 F298 M402 L403 V406 L486 Y489	P290-L294 WeakPolarHBondContact O-CB 3.3Å; P290-L294 PolarHBondContact O-N 3.18Å; P290-L294 VanDerWaalsContact O-N 3.08Å; Y291-L294 PolarHBondContact O-N 3.36Å; Y291-L294 VanDerWaalsContact O-N 3.08Å; L294-G297 PolarHBondContact O-N 2.95Å; L294-F298 HydrophobicContact CD1-CD2 3.92Å; L294-F298 HydrophobicContact CD1-CE2 3.51Å; L294-F298 HydrophobicContact CD2-CE2 4.37Å; L294-F298 HydrophobicContact CG-CD2 3.82Å; L294-F298 HydrophobicContact CG-CE2 3.85Å; L294-F298 WeakPolarHBondContact O-CD2 3.16Å; L294-F298 PolarHBondContact O-N 2.65Å; L294-M402 HydrophobicContact CD1-CB 4.14Å; L294-M402 HydrophobicContact CD1-CE 3.85Å; L294-M402 HydrophobicContact CD2-CB 4.32Å; L294-L403 HydrophobicContact CD2-CD1 4.47Å; L294-V406 HydrophobicContact CB-CG2 4.34Å; L294-V406 HydrophobicContact CD2-CG2 3.49Å; L294-V406 VanDerWaalsContact CD2-CG2 3.49Å; L294-V406 HydrophobicContact CG-CG2 4.41Å; L294-L486 HydrophobicContact CD1-CD2 4.03Å; L294-Y489 HydrophobicContact CB-CD2 4.21Å; L294-Y489 HydrophobicContact CB-CE2 3.87Å; L294-Y489 HydrophobicContact CD1-CD2 4.14Å; L294-Y489 HydrophobicContact CD1-CE1 4.32Å; L294-Y489 HydrophobicContact CD1-CE2 3.79Å; L294-Y489 HydrophobicContact CG-CE2 4.31Å
295	V	90.8	Very high	89.1	Confident	7 Å²	7	28.4 Å²	28.4	4%	0.042	17%	0.171	C	C	.	.	H	α-helix	trans	-62.7	-45	-179.3	174.6	0	0	0	0	110.8	Y291 F298 L299 Y428 F431	Y291-V295 HydrophobicContact CD1-CG2 4.04Å; Y291-V295 HydrophobicContact CD2-CG2 3.82Å; Y291-V295 HydrophobicContact CE1-CG2 3.61Å; Y291-V295 HydrophobicContact CE2-CG2 3.41Å; Y291-V295 VanDerWaalsContact CE2-CG2 3.41Å; Y291-V295 HydrophobicContact CG-CG2 4.15Å; Y291-V295 WeakPolarHBondContact O-CG2 3.5Å; Y291-V295 PolarHBondContact O-N 3.08Å; V295-F298 PolarHBondContact O-N 3.13Å; V295-L299 WeakPolarHBondContact O-CB 3.49Å; V295-L299 PolarHBondContact O-N 3.42Å; V295-Y428 HydrophobicContact CG2-CD2 4.35Å; V295-F431 HydrophobicContact CG1-CB 4.29Å; V295-F431 HydrophobicContact CG1-CD2 3.99Å; V295-F431 HydrophobicContact CG1-CG 4.34Å
296	M	91.1	Very high	89.7	Confident	84 Å²	84	30 Å²	30	41%	0.414	18%	0.178	S	C	.	.	H	α-helix	trans	-63.8	-43.2	178	-71.8	-59.5	-60	0	0	112	A292 L299 F300 I485	A292-M296 VanDerWaalsContact O-CB 3.3Å; A292-M296 WeakPolarHBondContact O-CB 3.17Å; A292-M296 WeakPolarHBondContact O-CG 3.49Å; A292-M296 PolarHBondContact O-N 3.31Å; M296-L299 PolarHBondContact O-N 3.18Å; M296-F300 HydrophobicContact CE-CE2 3.68Å; M296-F300 HydrophobicContact CE-CZ 4.14Å; M296-F300 WeakPolarHBondContact O-CD2 3.35Å; M296-F300 PolarHBondContact O-N 2.87Å; M296-I485 HydrophobicContact CB-CG2 4.36Å
297	G	91.6	Very high	90.3	Very high	0 Å²	0	26 Å²	26	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-58.8	-49.5	176.4	0	0	0	0	0	112.2	K293 L294 F300 T301 G482	K293-G297 PolarHBondContact O-N 3.2Å; L294-G297 PolarHBondContact O-N 2.95Å; G297-F300 PolarHBondContact O-N 3.15Å; G297-T301 PolarHBondContact O-N 2.92Å; G297-T301 PolarHBondContact O-OG1 3.37Å; G297-G482 WeakPolarHBondContact O-CA 3.4Å
298	F	90.8	Very high	90.7	Very high	4 Å²	4	23.8 Å²	23.8	2%	0.018	13%	0.132	C	C	.	.	H	α-helix	trans	-70.6	-32.8	178	-78.6	-56.2	0	0	0	113.7	L294 V295 F300 T301 S302 L398 P399 M402 Y428	L294-F298 HydrophobicContact CD1-CD2 3.92Å; L294-F298 HydrophobicContact CD1-CE2 3.51Å; L294-F298 HydrophobicContact CD2-CE2 4.37Å; L294-F298 HydrophobicContact CG-CD2 3.82Å; L294-F298 HydrophobicContact CG-CE2 3.85Å; L294-F298 WeakPolarHBondContact O-CD2 3.16Å; L294-F298 PolarHBondContact O-N 2.65Å; V295-F298 PolarHBondContact O-N 3.13Å; F298-F300 VanDerWaalsContact C-N 3.32Å; F298-F300 PolarHBondContact O-N 3.28Å; F298-T301 VanDerWaalsContact CA-OG1 3.31Å; F298-T301 WeakPolarHBondContact CA-OG1 3.35Å; F298-T301 PolarHBondContact O-N 2.93Å; F298-T301 PolarHBondContact O-OG1 3.26Å; F298-S302 VanDerWaalsContact O-CB 3.24Å; F298-S302 WeakPolarHBondContact O-CB 3.38Å; F298-S302 PolarHBondContact O-N 3.27Å; F298-S302 PolarHBondContact O-OG 3.2Å; F298-L398 HydrophobicContact CE1-CB 4.04Å; F298-L398 HydrophobicContact CZ-CB 4.19Å; F298-P399 HydrophobicContact CD1-CB 4.03Å; F298-P399 HydrophobicContact CD1-CG 3.63Å; F298-P399 HydrophobicContact CD2-CB 4.03Å; F298-P399 HydrophobicContact CE1-CB 4.14Å; F298-P399 HydrophobicContact CE1-CG 3.74Å; F298-P399 HydrophobicContact CE2-CB 4.13Å; F298-P399 HydrophobicContact CG-CB 3.98Å; F298-P399 HydrophobicContact CG-CG 4.05Å; F298-P399 HydrophobicContact CZ-CB 4.19Å; F298-P399 HydrophobicContact CZ-CG 4.25Å; F298-M402 HydrophobicContact CE2-CB 4.05Å; F298-M402 HydrophobicContact CE2-SD 4.05Å; F298-M402 HydrophobicContact CZ-CB 4.33Å; F298-M402 HydrophobicContact CZ-CG 4.35Å; F298-M402 HydrophobicContact CZ-SD 3.63Å; F298-Y428 HydrophobicContact CB-CE2 4.02Å
299	L	92.1	Very high	90.7	Very high	25 Å²	25	24.1 Å²	24.1	13%	0.131	14%	0.135	C	C	.	.	H	α-helix	trans	-57.2	-47.7	175.2	-178.6	156.3	0	0	0	110.5	V295 M296 S302 L303 F431 A435	V295-L299 WeakPolarHBondContact O-CB 3.49Å; V295-L299 PolarHBondContact O-N 3.42Å; M296-L299 PolarHBondContact O-N 3.18Å; L299-S302 PolarHBondContact O-N 3.03Å; L299-L303 WeakPolarHBondContact O-CB 3.34Å; L299-L303 PolarHBondContact O-N 3.46Å; L299-F431 HydrophobicContact CD1-CB 4.08Å; L299-F431 HydrophobicContact CD1-CD1 4.25Å; L299-F431 HydrophobicContact CD1-CG 4.45Å; L299-A435 HydrophobicContact CD2-CB 4.28Å; L299-A435 HydrophobicContact CG-CB 4.01Å
300	F	93.2	Very high	90.7	Very high	48 Å²	48	22.4 Å²	22.4	21%	0.211	12%	0.117	C	C	.	.	H	α-helix	trans	-66.9	-41.7	178.6	-75.1	-64.7	0	0	0	112.7	M296 G297 F298 L303 A304 L478 I481 I485	M296-F300 HydrophobicContact CE-CE2 3.68Å; M296-F300 HydrophobicContact CE-CZ 4.14Å; M296-F300 WeakPolarHBondContact O-CD2 3.35Å; M296-F300 PolarHBondContact O-N 2.87Å; G297-F300 PolarHBondContact O-N 3.15Å; F298-F300 VanDerWaalsContact C-N 3.32Å; F298-F300 PolarHBondContact O-N 3.28Å; F300-L303 PolarHBondContact O-N 3.38Å; F300-A304 PolarHBondContact O-N 3.17Å; F300-A304 VanDerWaalsContact O-N 3.1Å; F300-L478 HydrophobicContact CD1-CD2 3.87Å; F300-L478 HydrophobicContact CE1-CD2 4.43Å; F300-I481 HydrophobicContact CD1-CG2 4.36Å; F300-I481 HydrophobicContact CD2-CG2 3.92Å; F300-I481 HydrophobicContact CE1-CG2 4.47Å; F300-I481 HydrophobicContact CE2-CG2 4.05Å; F300-I481 HydrophobicContact CG-CG2 4.09Å; F300-I481 HydrophobicContact CZ-CG2 4.32Å; F300-I485 HydrophobicContact CD2-CD1 3.58Å; F300-I485 HydrophobicContact CE2-CD1 3.59Å
301	T	91.2	Very high	90.7	Very high	5 Å²	5	21.5 Å²	21.5	3%	0.031	11%	0.111	C	C	.	.	H	α-helix	trans	-65.8	-42.5	176	55.8	0	0	0	0	111.6	G297 F298 A304 F305	G297-T301 PolarHBondContact O-N 2.92Å; G297-T301 PolarHBondContact O-OG1 3.37Å; F298-T301 VanDerWaalsContact CA-OG1 3.31Å; F298-T301 WeakPolarHBondContact CA-OG1 3.35Å; F298-T301 PolarHBondContact O-N 2.93Å; F298-T301 PolarHBondContact O-OG1 3.26Å; T301-A304 VanDerWaalsContact O-CB 3.31Å; T301-A304 WeakPolarHBondContact O-CB 3.4Å; T301-A304 PolarHBondContact O-N 3.2Å; T301-F305 WeakPolarHBondContact O-CD2 3.45Å; T301-F305 PolarHBondContact O-N 2.96Å
302	S	90.5	Very high	90.6	Very high	21 Å²	21	21.9 Å²	21.9	15%	0.147	11%	0.113	C	C	.	.	H	α-helix	trans	-66.1	-39	177.3	-65.5	0	0	0	0	111.4	F298 L299 A304 F305 M306	F298-S302 VanDerWaalsContact O-CB 3.24Å; F298-S302 WeakPolarHBondContact O-CB 3.38Å; F298-S302 PolarHBondContact O-N 3.27Å; F298-S302 PolarHBondContact O-OG 3.2Å; L299-S302 PolarHBondContact O-N 3.03Å; S302-A304 VanDerWaalsContact C-N 3.26Å; S302-A304 PolarHBondContact O-N 3.43Å; S302-F305 PolarHBondContact O-N 2.69Å; S302-M306 WeakPolarHBondContact O-CB 3.35Å; S302-M306 WeakPolarHBondContact O-CG 3.3Å; S302-M306 PolarHBondContact O-N 3.41Å
303	L	92.1	Very high	90.5	Very high	26 Å²	26	20.4 Å²	20.4	14%	0.136	10%	0.101	C	C	.	.	H	α-helix	trans	-57.3	-41.3	173.5	-172.5	74.4	0	0	0	111.3	L299 F300 M306 L307 A435 S439 L478	L299-L303 WeakPolarHBondContact O-CB 3.34Å; L299-L303 PolarHBondContact O-N 3.46Å; F300-L303 PolarHBondContact O-N 3.38Å; L303-M306 PolarHBondContact O-N 3.29Å; L303-L307 WeakPolarHBondContact O-CB 3.47Å; L303-L307 PolarHBondContact O-N 3.01Å; L303-A435 HydrophobicContact CD1-CB 3.93Å; L303-A435 WeakPolarHBondContact CD1-O 3.42Å; L303-S439 VanDerWaalsContact CD1-CB 3.48Å; L303-L478 HydrophobicContact CB-CD1 4.45Å; L303-L478 HydrophobicContact CD2-CD1 3.83Å; L303-L478 HydrophobicContact CD2-CD2 4Å; L303-L478 HydrophobicContact CG-CD1 4.03Å
304	A	92.5	Very high	90.2	Very high	0 Å²	0	16.5 Å²	16.5	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-61.2	-46.8	176	0	0	0	0	0	112.6	F300 T301 S302 L307 L308 P475 L478 I479	F300-A304 PolarHBondContact O-N 3.17Å; F300-A304 VanDerWaalsContact O-N 3.1Å; T301-A304 VanDerWaalsContact O-CB 3.31Å; T301-A304 WeakPolarHBondContact O-CB 3.4Å; T301-A304 PolarHBondContact O-N 3.2Å; S302-A304 VanDerWaalsContact C-N 3.26Å; S302-A304 PolarHBondContact O-N 3.43Å; A304-L307 PolarHBondContact O-N 2.95Å; A304-L308 PolarHBondContact O-N 2.9Å; A304-L308 VanDerWaalsContact O-N 3.09Å; A304-P475 HydrophobicContact CB-CB 3.91Å; A304-P475 WeakPolarHBondContact CB-O 3Å; A304-L478 HydrophobicContact CB-CB 3.89Å; A304-L478 HydrophobicContact CB-CD1 4.46Å; A304-I479 HydrophobicContact CB-CD1 4.21Å; A304-I479 HydrophobicContact CB-CG1 3.69Å
305	F	90.2	Very high	90	Very high	16 Å²	16	16.4 Å²	16.4	7%	0.07	8%	0.083	C	C	.	.	H	α-helix	trans	-68.7	-35.9	177.9	-76.7	-77.2	0	0	0	112.6	T301 S302 L308 E309 A364 V392 A395	T301-F305 WeakPolarHBondContact O-CD2 3.45Å; T301-F305 PolarHBondContact O-N 2.96Å; S302-F305 PolarHBondContact O-N 2.69Å; F305-L308 WeakPolarHBondContact O-CB 3.24Å; F305-L308 PolarHBondContact O-N 2.87Å; F305-E309 WeakPolarHBondContact O-CB 3.39Å; F305-E309 PolarHBondContact O-N 3.37Å; F305-A364 HydrophobicContact CE1-CB 4.03Å; F305-A364 HydrophobicContact CZ-CB 3.72Å; F305-V392 HydrophobicContact CD1-CG2 4.08Å; F305-V392 HydrophobicContact CE1-CG2 4Å; F305-A395 HydrophobicContact CD1-CB 4.32Å; F305-A395 HydrophobicContact CD2-CB 3.48Å; F305-A395 VanDerWaalsContact CD2-CB 3.48Å; F305-A395 HydrophobicContact CE1-CB 4.05Å; F305-A395 HydrophobicContact CE2-CB 3.2Å; F305-A395 HydrophobicContact CG-CB 4.06Å; F305-A395 HydrophobicContact CZ-CB 3.5Å; F305-A395 VanDerWaalsContact CZ-CB 3.5Å
306	M	90.3	Very high	89.7	Confident	36 Å²	36	16.1 Å²	16.1	18%	0.177	8%	0.081	C	C	.	.	H	α-helix	trans	-69.6	-35.4	176.9	-66.8	-74.4	136.7	0	0	112	S302 L303 E309 G310 S436	S302-M306 WeakPolarHBondContact O-CB 3.35Å; S302-M306 WeakPolarHBondContact O-CG 3.3Å; S302-M306 PolarHBondContact O-N 3.41Å; L303-M306 PolarHBondContact O-N 3.29Å; M306-E309 WeakPolarHBondContact CE-OE2 3.47Å; M306-E309 PolarHBondContact O-N 2.97Å; M306-G310 PolarHBondContact O-N 3.47Å; M306-S436 PolarHBondContact SD-OG 3.34Å; M306-S436 VanDerWaalsContact SD-OG 3.4Å
307	L	91.3	Very high	89.1	Confident	13 Å²	13	12.2 Å²	12.2	7%	0.068	6%	0.062	C	C	.	.	H	α-helix	trans	-63	-44.6	171	-86.1	174.5	0	0	0	110.9	L303 A304 N311 S439 L470 P475 L478	L303-L307 WeakPolarHBondContact O-CB 3.47Å; L303-L307 PolarHBondContact O-N 3.01Å; A304-L307 PolarHBondContact O-N 2.95Å; L307-N311 PolarHBondContact O-N 3.49Å; L307-N311 PolarHBondContact O-ND2 2.97Å; L307-S439 VanDerWaalsContact CA-OG 3.27Å; L307-S439 WeakPolarHBondContact CA-OG 3.36Å; L307-S439 WeakPolarHBondContact CD2-O 3.23Å; L307-S439 WeakPolarHBondContact CD2-OG 3.38Å; L307-S439 WeakPolarHBondContact CG-OG 3.15Å; L307-S439 PolarHBondContact N-OG 3.05Å; L307-S439 VanDerWaalsContact N-OG 3.15Å; L307-L470 HydrophobicContact CD2-CD2 4.49Å; L307-P475 HydrophobicContact CB-CG 4.15Å; L307-L478 HydrophobicContact CD1-CD1 3.61Å
308	L	89.9	Confident	88.4	Confident	17 Å²	17	13.1 Å²	13.1	9%	0.089	7%	0.07	C	C	.	.	H	α-helix	trans	-60.1	-53	174.5	177.6	63.6	0	0	0	110.4	A304 F305 G310 N311 F312 M368 V471	A304-L308 PolarHBondContact O-N 2.9Å; A304-L308 VanDerWaalsContact O-N 3.09Å; F305-L308 WeakPolarHBondContact O-CB 3.24Å; F305-L308 PolarHBondContact O-N 2.87Å; L308-G310 PolarHBondContact O-N 3.04Å; L308-N311 PolarHBondContact O-N 3.28Å; L308-F312 HydrophobicContact CD1-CD2 4.02Å; L308-F312 WeakPolarHBondContact O-CB 3.49Å; L308-F312 PolarHBondContact O-N 2.97Å; L308-M368 HydrophobicContact CB-CE 4.42Å; L308-M368 HydrophobicContact CD2-CE 3.85Å; L308-V471 HydrophobicContact CD1-CB 4.44Å; L308-V471 HydrophobicContact CD1-CG1 3.67Å
309	E	88.8	Confident	87.7	Confident	29 Å²	29	13.9 Å²	13.9	14%	0.136	8%	0.075	C	C	.	.	H	α-helix	trans	-52.7	-52.4	-178.5	-172.2	-176	150.3	0	0	112.5	F61 F305 M306 N311	F61-E309 HydrophobicContact CD1-CG 3.93Å; F61-E309 WeakPolarHBondContact CD1-O 3.23Å; F61-E309 HydrophobicContact CD2-CG 4.4Å; F61-E309 HydrophobicContact CE1-CB 4.22Å; F61-E309 HydrophobicContact CE1-CG 3.51Å; F61-E309 HydrophobicContact CE2-CG 4.01Å; F61-E309 HydrophobicContact CG-CG 4.37Å; F61-E309 HydrophobicContact CZ-CB 4.49Å; F61-E309 HydrophobicContact CZ-CG 3.54Å; F305-E309 WeakPolarHBondContact O-CB 3.39Å; F305-E309 PolarHBondContact O-N 3.37Å; M306-E309 WeakPolarHBondContact CE-OE2 3.47Å; M306-E309 PolarHBondContact O-N 2.97Å; E309-N311 PolarHBondContact O-N 3.06Å
310	G	87.1	Confident	86.9	Confident	2 Å²	2	13.5 Å²	13.5	2%	0.021	7%	0.073	C	C	.	.	H	α-helix	trans	-67.1	-31.5	-176	0	0	0	0	0	114.3	Q64 M306 L308	Q64-G310 PolarHBondContact OE1-O 3.32Å; Q64-G310 VanDerWaalsContact OE1-O 3.09Å; M306-G310 PolarHBondContact O-N 3.47Å; L308-G310 PolarHBondContact O-N 3.04Å
311	N	90.1	Very high	85.8	Confident	0 Å²	0	13.5 Å²	13.5	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-101.7	-13.7	-174.7	-62.6	-74.7	0	0	0	114.3	Q64 L307 L308 E309 A313 L314 F315 S443 V471	Q64-N311 PolarHBondContact NE2-OD1 3.38Å; L307-N311 PolarHBondContact O-N 3.49Å; L307-N311 PolarHBondContact O-ND2 2.97Å; L308-N311 PolarHBondContact O-N 3.28Å; E309-N311 PolarHBondContact O-N 3.06Å; N311-A313 VanDerWaalsContact C-N 3.31Å; N311-A313 PolarHBondContact O-N 3.04Å; N311-L314 PolarHBondContact O-N 3.27Å; N311-L314 VanDerWaalsContact O-N 3.16Å; N311-F315 WeakPolarHBondContact O-CB 3.39Å; N311-F315 PolarHBondContact O-N 3.21Å; N311-S443 PolarHBondContact ND2-OG 3.06Å; N311-S443 PolarHBondContact OD1-OG 3.2Å; N311-V471 HydrophobicContact CB-CG2 3.89Å
312	F	87.9	Confident	84.8	Confident	10 Å²	10	14.3 Å²	14.3	4%	0.044	9%	0.089	C	C	.	.	H	α-helix	trans	-61.1	-39.3	-173.2	-172.3	-99.9	0	0	0	112.7	L308 F315 C316 I329 L330 I333 V371	L308-F312 HydrophobicContact CD1-CD2 4.02Å; L308-F312 WeakPolarHBondContact O-CB 3.49Å; L308-F312 PolarHBondContact O-N 2.97Å; F312-F315 PolarHBondContact O-N 3.38Å; F312-C316 VanDerWaalsContact CE1-SG 3.57Å; F312-C316 PolarHBondContact O-N 3.28Å; F312-C316 PolarHBondContact O-SG 3.09Å; F312-I329 HydrophobicContact CE1-CG2 3.79Å; F312-I329 HydrophobicContact CZ-CG2 3.81Å; F312-L330 HydrophobicContact CD1-CD2 3.48Å; F312-L330 VanDerWaalsContact CD1-CD2 3.48Å; F312-L330 HydrophobicContact CD1-CG 4.14Å; F312-L330 HydrophobicContact CE1-CD2 3.93Å; F312-L330 HydrophobicContact CE1-CG 4.32Å; F312-I333 HydrophobicContact CD1-CD1 4.29Å; F312-I333 HydrophobicContact CE1-CD1 3.57Å; F312-I333 HydrophobicContact CE2-CD1 4.39Å; F312-I333 HydrophobicContact CZ-CD1 3.63Å; F312-V371 HydrophobicContact CE2-CG1 4.42Å
313	A	86.2	Confident	83.8	Confident	1 Å²	1	14.8 Å²	14.8	1%	0.008	9%	0.088	C	C	.	.	H	α-helix	trans	-62.5	-43.9	176.9	0	0	0	0	0	111.8	F61 L65 N311 S317 F326	F61-A313 WeakPolarHBondContact O-CB 3.44Å; L65-A313 HydrophobicContact CD1-CB 4.17Å; N311-A313 VanDerWaalsContact C-N 3.31Å; N311-A313 PolarHBondContact O-N 3.04Å; A313-S317 WeakPolarHBondContact O-CB 3.4Å; A313-S317 PolarHBondContact O-N 3.03Å; A313-S317 VanDerWaalsContact O-N 3.11Å; A313-S317 PolarHBondContact O-OG 2.98Å; A313-F326 HydrophobicContact CB-CD2 4.29Å; A313-F326 HydrophobicContact CB-CE2 4.14Å
314	L	86.3	Confident	82.8	Confident	1 Å²	1	21.5 Å²	21.5	1%	0.005	12%	0.116	C	C	.	.	H	α-helix	trans	-67.7	-39.1	175.9	-73.9	174.2	0	0	0	112.4	Q64 L65 L68 N311 S317 A318 L447 L467	Q64-L314 HydrophobicContact CG-CD1 3.89Å; L65-L314 HydrophobicContact CB-CD2 4.37Å; L65-L314 HydrophobicContact CD1-CD2 4.42Å; L65-L314 HydrophobicContact CG-CD2 4.4Å; L68-L314 HydrophobicContact CD1-CD1 3.79Å; L68-L314 HydrophobicContact CD1-CD2 4.1Å; N311-L314 PolarHBondContact O-N 3.27Å; N311-L314 VanDerWaalsContact O-N 3.16Å; L314-S317 PolarHBondContact O-N 3.42Å; L314-S317 PolarHBondContact O-OG 3.18Å; L314-A318 WeakPolarHBondContact O-CB 3.37Å; L314-A318 PolarHBondContact O-N 3.09Å; L314-L447 HydrophobicContact CD1-CD1 3.88Å; L314-L467 HydrophobicContact CB-CD2 4.22Å
315	F	86.9	Confident	82.1	Confident	0 Å²	0	23.8 Å²	23.8	0%	0	13%	0.128	C	C	.	.	I	π-helix	trans	-62.1	-45.5	176.4	176.8	-99.2	0	0	0	111.7	N311 F312 S317 T319 L320 V371 V372 L467 K468 V471	N311-F315 WeakPolarHBondContact O-CB 3.39Å; N311-F315 PolarHBondContact O-N 3.21Å; F312-F315 PolarHBondContact O-N 3.38Å; F315-S317 VanDerWaalsContact C-N 3.34Å; F315-S317 PolarHBondContact O-N 3.12Å; F315-T319 HydrophobicContact CD2-CG2 4Å; F315-T319 HydrophobicContact CE2-CG2 3.52Å; F315-T319 HydrophobicContact CZ-CG2 4.07Å; F315-T319 WeakPolarHBondContact O-CA 3.32Å; F315-T319 VanDerWaalsContact O-CB 3.23Å; F315-T319 WeakPolarHBondContact O-CB 3.42Å; F315-T319 PolarHBondContact O-N 3.4Å; F315-L320 HydrophobicContact CD1-CD1 4.12Å; F315-L320 HydrophobicContact CD1-CG 4.26Å; F315-L320 HydrophobicContact CE1-CD1 3.68Å; F315-L320 HydrophobicContact CE1-CD2 4.16Å; F315-L320 HydrophobicContact CE1-CG 3.73Å; F315-L320 HydrophobicContact CZ-CD2 4.28Å; F315-L320 HydrophobicContact CZ-CG 4.21Å; F315-L320 PolarHBondContact O-N 3.18Å; F315-L320 VanDerWaalsContact O-N 3.15Å; F315-V371 HydrophobicContact CD1-CG1 4.01Å; F315-V371 HydrophobicContact CE1-CG1 3.33Å; F315-V371 HydrophobicContact CZ-CG1 4.01Å; F315-V372 HydrophobicContact CZ-CG2 4.27Å; F315-L467 HydrophobicContact CD2-CB 4.1Å; F315-K468 HydrophobicContact CE2-CG 3.91Å; F315-V471 HydrophobicContact CB-CG2 3.85Å; F315-V471 HydrophobicContact CD1-CG1 4.36Å; F315-V471 HydrophobicContact CD2-CG2 4.37Å; F315-V471 HydrophobicContact CG-CG1 4.36Å; F315-V471 HydrophobicContact CG-CG2 4.11Å
316	C	83.4	Confident	81.8	Confident	0 Å²	0	23 Å²	23	0%	0	13%	0.125	C	C	.	.	I	π-helix	trans	-63.1	-40.3	177	-67.3	0	0	0	0	112.6	F312 G321 F322 F326	F312-C316 VanDerWaalsContact CE1-SG 3.57Å; F312-C316 PolarHBondContact O-N 3.28Å; F312-C316 PolarHBondContact O-SG 3.09Å; C316-G321 PolarHBondContact O-N 2.73Å; C316-F322 PolarHBondContact O-N 2.9Å; C316-F326 HydrophobicContact CB-CB 3.44Å; C316-F326 VanDerWaalsContact CB-CB 3.44Å; C316-F326 HydrophobicContact CB-CG 4.42Å
317	S	79.1	Confident	81.5	Confident	2 Å²	2	21.4 Å²	21.4	1%	0.014	12%	0.117	C	C	.	.	I	π-helix	trans	-78.2	-43.3	-176.5	71.6	0	0	0	0	113	A313 L314 F315 R323	A313-S317 WeakPolarHBondContact O-CB 3.4Å; A313-S317 PolarHBondContact O-N 3.03Å; A313-S317 VanDerWaalsContact O-N 3.11Å; A313-S317 PolarHBondContact O-OG 2.98Å; L314-S317 PolarHBondContact O-N 3.42Å; L314-S317 PolarHBondContact O-OG 3.18Å; F315-S317 VanDerWaalsContact C-N 3.34Å; F315-S317 PolarHBondContact O-N 3.12Å; S317-R323 WeakPolarHBondContact O-CG 3.18Å
318	A	77.1	Confident	81.3	Confident	19 Å²	19	23.3 Å²	23.3	16%	0.157	13%	0.127	C	C	.	.	I	π-helix	trans	-93.6	-34	-171.3	0	0	0	0	0	113.8	L314 Y452 Q459 L467	L314-A318 WeakPolarHBondContact O-CB 3.37Å; L314-A318 PolarHBondContact O-N 3.09Å; A318-Y452 HydrophobicContact CB-CE2 4.45Å; A318-Q459 HydrophobicContact CB-CG 4Å; A318-L467 HydrophobicContact CB-CD1 4.01Å
319	T	76	Confident	81.3	Confident	21 Å²	21	22.5 Å²	22.5	13%	0.129	12%	0.123	C	C	.	.	I	π-helix	trans	-99.5	-54.6	-176.1	-58.8	0	0	0	0	112.2	F315 G321 D464	F315-T319 HydrophobicContact CD2-CG2 4Å; F315-T319 HydrophobicContact CE2-CG2 3.52Å; F315-T319 HydrophobicContact CZ-CG2 4.07Å; F315-T319 WeakPolarHBondContact O-CA 3.32Å; F315-T319 VanDerWaalsContact O-CB 3.23Å; F315-T319 WeakPolarHBondContact O-CB 3.42Å; F315-T319 PolarHBondContact O-N 3.4Å; T319-G321 VanDerWaalsContact C-N 3.33Å; T319-G321 PolarHBondContact O-N 3.19Å; T319-D464 WeakPolarHBondContact CG2-OD1 3.24Å
320	L	74.3	Confident	81.3	Confident	17 Å²	17	21.1 Å²	21.1	9%	0.089	12%	0.116	C	C	.	.	I	π-helix	trans	-75	-24.8	-177.9	-65	178.3	0	0	0	112.7	F315 F322 T381	F315-L320 HydrophobicContact CD1-CD1 4.12Å; F315-L320 HydrophobicContact CD1-CG 4.26Å; F315-L320 HydrophobicContact CE1-CD1 3.68Å; F315-L320 HydrophobicContact CE1-CD2 4.16Å; F315-L320 HydrophobicContact CE1-CG 3.73Å; F315-L320 HydrophobicContact CZ-CD2 4.28Å; F315-L320 HydrophobicContact CZ-CG 4.21Å; F315-L320 PolarHBondContact O-N 3.18Å; F315-L320 VanDerWaalsContact O-N 3.15Å; L320-F322 VanDerWaalsContact C-N 3.28Å; L320-F322 HydrophobicContact CB-CD2 3.66Å; L320-F322 HydrophobicContact CB-CE2 4.05Å; L320-F322 HydrophobicContact CB-CG 4.24Å; L320-F322 HydrophobicContact CD1-CD2 4.02Å; L320-F322 HydrophobicContact CD1-CE2 4.28Å; L320-F322 HydrophobicContact CG-CD2 4.44Å; L320-T381 HydrophobicContact CD1-CG2 4.5Å
321	G	70.3	Confident	81.5	Confident	47 Å²	47	23.1 Å²	23.1	49%	0.485	13%	0.126	S	C	.	.			trans	77.8	10.8	-177.1	0	0	0	0	0	113.7	C316 T319 R323	C316-G321 PolarHBondContact O-N 2.73Å; T319-G321 VanDerWaalsContact C-N 3.33Å; T319-G321 PolarHBondContact O-N 3.19Å; G321-R323 PolarHBondContact O-N 3.21Å
322	F	71.8	Confident	81.6	Confident	22 Å²	22	25 Å²	25	10%	0.096	14%	0.138	C	C	.	.			trans	-85.3	52.2	178	-61.2	-39.3	0	0	0	112	C316 L320 K324 D325 F326 I329 K376 L378 T381	C316-F322 PolarHBondContact O-N 2.9Å; L320-F322 VanDerWaalsContact C-N 3.28Å; L320-F322 HydrophobicContact CB-CD2 3.66Å; L320-F322 HydrophobicContact CB-CE2 4.05Å; L320-F322 HydrophobicContact CB-CG 4.24Å; L320-F322 HydrophobicContact CD1-CD2 4.02Å; L320-F322 HydrophobicContact CD1-CE2 4.28Å; L320-F322 HydrophobicContact CG-CD2 4.44Å; F322-K324 PolarHBondContact O-N 3.16Å; F322-D325 HydrophobicContact CB-CB 4.48Å; F322-D325 PolarHBondContact O-N 3.46Å; F322-F326 PolarHBondContact O-N 2.99Å; F322-I329 HydrophobicContact CD2-CD1 4.35Å; F322-K376 HydrophobicContact CZ-CB 4.24Å; F322-L378 HydrophobicContact CD1-CD2 3.37Å; F322-L378 HydrophobicContact CD1-CG 4.17Å; F322-L378 HydrophobicContact CD2-CD2 4.04Å; F322-L378 HydrophobicContact CE1-CD2 3.33Å; F322-L378 HydrophobicContact CE1-CG 3.66Å; F322-L378 HydrophobicContact CE2-CD2 4.01Å; F322-L378 HydrophobicContact CG-CD2 3.75Å; F322-L378 HydrophobicContact CZ-CD2 3.66Å; F322-L378 HydrophobicContact CZ-CG 3.94Å; F322-T381 HydrophobicContact CE2-CG2 4.46Å
323	R	68.2	Low	81.8	Confident	31 Å²	31	25 Å²	25	12%	0.117	14%	0.138	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.1	-28.2	-178.4	-71.7	-169.4	-150.1	-115.9	2	114.1	S317 G321 F326 G456 C457	S317-R323 WeakPolarHBondContact O-CG 3.18Å; G321-R323 PolarHBondContact O-N 3.21Å; R323-F326 WeakPolarHBondContact O-CD1 3.47Å; R323-F326 WeakPolarHBondContact O-CE1 3.5Å; R323-G456 PolarHBondContact NH2-O 3.35Å; R323-C457 PolarHBondContact NH2-O 2.96Å
324	K	70.8	Confident	82.1	Confident	167 Å²	167	25.8 Å²	25.8	73%	0.726	14%	0.142	S	C	*	.	T	Hydrogen-bonded Turn	trans	-82.9	-36.7	178.1	-65.1	-176.4	179.3	-179.7	0	112.2	F322	F322-K324 PolarHBondContact O-N 3.16Å
325	D	79.3	Confident	82.4	Confident	49 Å²	49	30.1 Å²	30.1	26%	0.262	16%	0.164	S	C	.	.	T	Hydrogen-bonded Turn	trans	-98.7	-11	-168.3	-59.4	-54.4	0	0	0	114.7	F322 H327 N328 I329 L378	F322-D325 HydrophobicContact CB-CB 4.48Å; F322-D325 PolarHBondContact O-N 3.46Å; D325-H327 PolarHBondContact O-N 3.32Å; D325-H327 VanDerWaalsContact O-N 3.15Å; D325-N328 WeakPolarHBondContact O-CB 3.34Å; D325-N328 PolarHBondContact O-N 3.18Å; D325-I329 WeakPolarHBondContact O-CG1 3.36Å; D325-I329 PolarHBondContact O-N 3.49Å; D325-L378 HydrophobicContact CB-CD2 4.21Å
326	F	83	Confident	82.8	Confident	0 Å²	0	30.2 Å²	30.2	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-58.7	-33	-174.8	80.9	-92.5	0	0	0	114	F62 L65 A313 C316 F322 R323 N328 I329 L330	F62-F326 AromaticContact CE1-CE2 3.92Å; F62-F326 HydrophobicContact CE1-CE2 3.92Å; L65-F326 HydrophobicContact CD1-CE2 4.37Å; L65-F326 HydrophobicContact CD1-CZ 4.01Å; A313-F326 HydrophobicContact CB-CD2 4.29Å; A313-F326 HydrophobicContact CB-CE2 4.14Å; C316-F326 HydrophobicContact CB-CB 3.44Å; C316-F326 VanDerWaalsContact CB-CB 3.44Å; C316-F326 HydrophobicContact CB-CG 4.42Å; F322-F326 PolarHBondContact O-N 2.99Å; R323-F326 WeakPolarHBondContact O-CD1 3.47Å; R323-F326 WeakPolarHBondContact O-CE1 3.5Å; F326-N328 VanDerWaalsContact C-N 3.33Å; F326-N328 PolarHBondContact O-N 3.33Å; F326-I329 WeakPolarHBondContact O-CB 3.09Å; F326-I329 PolarHBondContact O-N 2.95Å; F326-L330 HydrophobicContact CD2-CD1 4Å; F326-L330 HydrophobicContact CE2-CD1 4.36Å; F326-L330 WeakPolarHBondContact O-CG 3.47Å; F326-L330 PolarHBondContact O-N 3.42Å
327	H	84.3	Confident	83.2	Confident	2 Å²	2	30.7 Å²	30.7	1%	0.009	17%	0.169	C	C	.	.	H	α-helix	trans	-63	-39.7	175.8	-53.5	98.3	0	0	0	112.1	F62 G204 D325 L330 L331	F62-H327 AromaticContact CE1-CD2 3.54Å; G204-H327 VanDerWaalsContact CA-CE1 3.4Å; G204-H327 WeakPolarHBondContact CA-CE1 3.36Å; G204-H327 WeakPolarHBondContact CA-ND1 3.45Å; D325-H327 PolarHBondContact O-N 3.32Å; D325-H327 VanDerWaalsContact O-N 3.15Å; H327-L330 PolarHBondContact O-N 3.38Å; H327-L331 WeakPolarHBondContact O-CB 3.21Å; H327-L331 PolarHBondContact O-N 3.45Å
328	N	87.6	Confident	83.8	Confident	52 Å²	52	32 Å²	32	28%	0.278	18%	0.177	S	C	.	.	H	α-helix	trans	-70.9	-37.1	177.2	-65.5	-26.8	0	0	0	110.7	Q201 D325 F326 L331 V332 Y382	Q201-N328 PolarHBondContact NE2-OD1 3.45Å; D325-N328 WeakPolarHBondContact O-CB 3.34Å; D325-N328 PolarHBondContact O-N 3.18Å; F326-N328 VanDerWaalsContact C-N 3.33Å; F326-N328 PolarHBondContact O-N 3.33Å; N328-L331 PolarHBondContact O-N 2.94Å; N328-V332 WeakPolarHBondContact O-CG2 3.49Å; N328-V332 PolarHBondContact O-N 3.43Å; N328-Y382 HydrophobicContact CB-CE1 4.27Å; N328-Y382 VanDerWaalsContact CB-OH 3.29Å; N328-Y382 WeakPolarHBondContact CB-OH 3.31Å
329	I	88.6	Confident	84.5	Confident	0 Å²	0	36.7 Å²	36.7	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-60.4	-49.9	174.1	-65	172	0	0	0	110.2	F312 F322 D325 F326 L331 V332 I333 T381 Y382 S385	F312-I329 HydrophobicContact CE1-CG2 3.79Å; F312-I329 HydrophobicContact CZ-CG2 3.81Å; F322-I329 HydrophobicContact CD2-CD1 4.35Å; D325-I329 WeakPolarHBondContact O-CG1 3.36Å; D325-I329 PolarHBondContact O-N 3.49Å; F326-I329 WeakPolarHBondContact O-CB 3.09Å; F326-I329 PolarHBondContact O-N 2.95Å; I329-L331 VanDerWaalsContact C-N 3.32Å; I329-L331 PolarHBondContact O-N 2.87Å; I329-V332 PolarHBondContact O-N 3.38Å; I329-V332 VanDerWaalsContact O-N 3.17Å; I329-I333 HydrophobicContact CG2-CD1 4.47Å; I329-I333 WeakPolarHBondContact O-CG1 3.44Å; I329-I333 PolarHBondContact O-N 3.07Å; I329-I333 VanDerWaalsContact O-N 3.1Å; I329-T381 HydrophobicContact CD1-CG2 3.76Å; I329-Y382 HydrophobicContact CG1-CD1 4.42Å; I329-Y382 HydrophobicContact CG1-CE1 4Å; I329-S385 WeakPolarHBondContact CG2-OG 3.48Å
330	L	89.4	Confident	85.4	Confident	0 Å²	0	36 Å²	36	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-57.2	-43.8	175.5	-77.4	172.5	0	0	0	112.2	F61 F62 T196 F312 F326 H327 V332 I333 M334	F61-L330 HydrophobicContact CB-CD1 4.31Å; F61-L330 HydrophobicContact CD1-CD1 4.29Å; F61-L330 HydrophobicContact CD1-CD2 3.45Å; F61-L330 VanDerWaalsContact CD1-CD2 3.45Å; F61-L330 HydrophobicContact CE1-CD2 3.42Å; F61-L330 VanDerWaalsContact CE1-CD2 3.42Å; F61-L330 HydrophobicContact CG-CD1 4.38Å; F61-L330 HydrophobicContact CG-CD2 4.13Å; F61-L330 HydrophobicContact CZ-CD2 4.1Å; F62-L330 HydrophobicContact CE1-CD1 4.33Å; F62-L330 HydrophobicContact CZ-CD1 4.02Å; T196-L330 HydrophobicContact CG2-CB 3.8Å; F312-L330 HydrophobicContact CD1-CD2 3.48Å; F312-L330 VanDerWaalsContact CD1-CD2 3.48Å; F312-L330 HydrophobicContact CD1-CG 4.14Å; F312-L330 HydrophobicContact CE1-CD2 3.93Å; F312-L330 HydrophobicContact CE1-CG 4.32Å; F326-L330 HydrophobicContact CD2-CD1 4Å; F326-L330 HydrophobicContact CE2-CD1 4.36Å; F326-L330 WeakPolarHBondContact O-CG 3.47Å; F326-L330 PolarHBondContact O-N 3.42Å; H327-L330 PolarHBondContact O-N 3.38Å; L330-V332 VanDerWaalsContact C-N 3.31Å; L330-V332 PolarHBondContact O-N 3.22Å; L330-I333 PolarHBondContact O-N 3.43Å; L330-M334 WeakPolarHBondContact O-CG 3.45Å; L330-M334 PolarHBondContact O-N 3.34Å
331	L	91.2	Very high	86.1	Confident	44 Å²	44	37.9 Å²	37.9	23%	0.23	21%	0.205	C	C	.	.	H	α-helix	trans	-60.1	-41.4	177.5	-175	65	0	0	0	111.8	V193 T196 A197 H327 N328 I329 M334 L335	V193-L331 HydrophobicContact CG1-CD1 4.24Å; T196-L331 HydrophobicContact CG2-CB 4.41Å; A197-L331 HydrophobicContact CB-CD1 3.8Å; H327-L331 WeakPolarHBondContact O-CB 3.21Å; H327-L331 PolarHBondContact O-N 3.45Å; N328-L331 PolarHBondContact O-N 2.94Å; I329-L331 VanDerWaalsContact C-N 3.32Å; I329-L331 PolarHBondContact O-N 2.87Å; L331-M334 PolarHBondContact O-N 3.4Å; L331-L335 VanDerWaalsContact O-CB 3.29Å; L331-L335 WeakPolarHBondContact O-CB 3.35Å; L331-L335 PolarHBondContact O-N 3.41Å
332	V	92.4	Very high	87.1	Confident	41 Å²	41	39.7 Å²	39.7	25%	0.248	21%	0.209	C	C	.	.	H	α-helix	trans	-63.6	-39.7	176.1	170	0	0	0	0	111.6	N328 I329 L330 S336 Y382 F386	N328-V332 WeakPolarHBondContact O-CG2 3.49Å; N328-V332 PolarHBondContact O-N 3.43Å; I329-V332 PolarHBondContact O-N 3.38Å; I329-V332 VanDerWaalsContact O-N 3.17Å; L330-V332 VanDerWaalsContact C-N 3.31Å; L330-V332 PolarHBondContact O-N 3.22Å; V332-S336 VanDerWaalsContact O-CB 3.3Å; V332-S336 WeakPolarHBondContact O-CB 3.47Å; V332-S336 PolarHBondContact O-N 3.17Å; V332-S336 PolarHBondContact O-OG 3.1Å; V332-Y382 HydrophobicContact CB-CD1 4.44Å; V332-Y382 HydrophobicContact CG2-CD1 3.91Å; V332-Y382 HydrophobicContact CG2-CE1 4.03Å; V332-F386 HydrophobicContact CG1-CB 4.13Å
333	I	91.6	Very high	88.1	Confident	9 Å²	9	43.4 Å²	43.4	5%	0.046	23%	0.225	C	C	.	.	H	α-helix	trans	-62.4	-48	175.9	-59.4	171.3	0	0	0	110.2	F312 I329 L330 S336 A337 S385 G389 V392	F312-I333 HydrophobicContact CD1-CD1 4.29Å; F312-I333 HydrophobicContact CE1-CD1 3.57Å; F312-I333 HydrophobicContact CE2-CD1 4.39Å; F312-I333 HydrophobicContact CZ-CD1 3.63Å; I329-I333 HydrophobicContact CG2-CD1 4.47Å; I329-I333 WeakPolarHBondContact O-CG1 3.44Å; I329-I333 PolarHBondContact O-N 3.07Å; I329-I333 VanDerWaalsContact O-N 3.1Å; L330-I333 PolarHBondContact O-N 3.43Å; I333-S336 WeakPolarHBondContact CA-OG 3.22Å; I333-S336 PolarHBondContact O-N 3.1Å; I333-S336 PolarHBondContact O-OG 2.93Å; I333-A337 VanDerWaalsContact O-CB 3.3Å; I333-A337 WeakPolarHBondContact O-CB 3.12Å; I333-A337 PolarHBondContact O-N 2.73Å; I333-S385 WeakPolarHBondContact CG1-O 3.49Å; I333-G389 WeakPolarHBondContact O-CA 3.46Å; I333-V392 HydrophobicContact CG2-CG2 4.5Å
334	M	91.9	Very high	89.1	Confident	18 Å²	18	42.3 Å²	42.3	9%	0.089	22%	0.221	C	C	.	.	H	α-helix	trans	-67.8	-39.3	-178	-65.2	-60.1	114	0	0	112.6	F61 V193 T196 L330 L331 T338	F61-M334 HydrophobicContact CE2-CE 3.79Å; F61-M334 HydrophobicContact CE2-SD 4.09Å; F61-M334 HydrophobicContact CZ-CE 3.47Å; F61-M334 VanDerWaalsContact CZ-CE 3.47Å; F61-M334 HydrophobicContact CZ-SD 4.38Å; V193-M334 HydrophobicContact CG2-CB 4.11Å; T196-M334 HydrophobicContact CG2-CG 4.23Å; L330-M334 WeakPolarHBondContact O-CG 3.45Å; L330-M334 PolarHBondContact O-N 3.34Å; L331-M334 PolarHBondContact O-N 3.4Å; M334-T338 PolarHBondContact O-N 2.7Å; M334-T338 PolarHBondContact O-OG1 3Å
335	L	93.7	Very high	90	Very high	91 Å²	91	38.9 Å²	38.9	48%	0.476	21%	0.207	S	C	.	.	H	α-helix	trans	-65.5	-46.9	177.1	-169	78.6	0	0	0	111.1	V193 L331 T338 L339	V193-L335 HydrophobicContact CG1-CD1 4.29Å; L331-L335 VanDerWaalsContact O-CB 3.29Å; L331-L335 WeakPolarHBondContact O-CB 3.35Å; L331-L335 PolarHBondContact O-N 3.41Å; L335-T338 WeakPolarHBondContact O-CB 3.23Å; L335-T338 PolarHBondContact O-N 2.93Å; L335-L339 HydrophobicContact CG-CD1 4.33Å; L335-L339 WeakPolarHBondContact O-CG 3.3Å; L335-L339 PolarHBondContact O-N 3.48Å
336	S	94.6	Very high	90.6	Very high	2 Å²	2	42.4 Å²	42.4	1%	0.014	22%	0.217	C	C	.	.	H	α-helix	trans	-65.6	-37.7	177.8	54.6	0	0	0	0	112.3	V332 I333 T338 L339 A340 F386 G389	V332-S336 VanDerWaalsContact O-CB 3.3Å; V332-S336 WeakPolarHBondContact O-CB 3.47Å; V332-S336 PolarHBondContact O-N 3.17Å; V332-S336 PolarHBondContact O-OG 3.1Å; I333-S336 WeakPolarHBondContact CA-OG 3.22Å; I333-S336 PolarHBondContact O-N 3.1Å; I333-S336 PolarHBondContact O-OG 2.93Å; S336-T338 VanDerWaalsContact C-N 3.34Å; S336-T338 PolarHBondContact O-N 3.17Å; S336-L339 PolarHBondContact O-N 2.86Å; S336-A340 VanDerWaalsContact O-CB 3.26Å; S336-A340 WeakPolarHBondContact O-CB 3.27Å; S336-A340 PolarHBondContact O-N 2.81Å; S336-F386 VanDerWaalsContact CB-CD2 3.49Å; S336-F386 WeakPolarHBondContact CB-O 3.28Å; S336-F386 PolarHBondContact OG-O 2.67Å; S336-G389 WeakPolarHBondContact OG-CA 3.02Å
337	A	92.3	Very high	91	Very high	11 Å²	11	43.9 Å²	43.9	9%	0.091	22%	0.223	C	C	.	.	H	α-helix	trans	-59.4	-45.8	172.7	0	0	0	0	0	111.8	I333 L339 A340 I341 G389 V392 A393	I333-A337 VanDerWaalsContact O-CB 3.3Å; I333-A337 WeakPolarHBondContact O-CB 3.12Å; I333-A337 PolarHBondContact O-N 2.73Å; A337-L339 PolarHBondContact O-N 2.86Å; A337-A340 PolarHBondContact O-N 3.16Å; A337-I341 WeakPolarHBondContact O-CG1 3.45Å; A337-I341 PolarHBondContact O-N 3.22Å; A337-G389 WeakPolarHBondContact CA-O 2.95Å; A337-G389 VanDerWaalsContact CB-O 3.26Å; A337-G389 WeakPolarHBondContact CB-O 3.13Å; A337-V392 HydrophobicContact CB-CB 4.48Å; A337-V392 HydrophobicContact CB-CG1 4.41Å; A337-A393 HydrophobicContact CB-CB 4.29Å; A337-A393 WeakPolarHBondContact O-CB 3.05Å
338	T	91.2	Very high	91.1	Very high	29 Å²	29	44.1 Å²	44.1	18%	0.178	22%	0.224	C	C	.	.	H	α-helix	trans	-60.9	-45.6	178.2	-59.5	0	0	0	0	112.1	V189 L190 V193 M334 L335 S336 A340 I341	V189-T338 HydrophobicContact CG1-CG2 3.5Å; V189-T338 VanDerWaalsContact CG1-CG2 3.5Å; V189-T338 WeakPolarHBondContact CG1-OG1 3.5Å; L190-T338 HydrophobicContact CD2-CG2 4.5Å; V193-T338 WeakPolarHBondContact CG2-OG1 3.19Å; M334-T338 PolarHBondContact O-N 2.7Å; M334-T338 PolarHBondContact O-OG1 3Å; L335-T338 WeakPolarHBondContact O-CB 3.23Å; L335-T338 PolarHBondContact O-N 2.93Å; S336-T338 VanDerWaalsContact C-N 3.34Å; S336-T338 PolarHBondContact O-N 3.17Å; T338-A340 VanDerWaalsContact C-N 3.27Å; T338-A340 PolarHBondContact O-N 3.39Å; T338-I341 PolarHBondContact O-N 3.24Å
339	L	93.1	Very high	91	Very high	117 Å²	117	47 Å²	47	61%	0.613	25%	0.245	S	C	*	.	H	α-helix	trans	-68.3	-25.4	178.5	-66.7	172.8	0	0	0	113	L335 S336 A337 P342	L335-L339 HydrophobicContact CG-CD1 4.33Å; L335-L339 WeakPolarHBondContact O-CG 3.3Å; L335-L339 PolarHBondContact O-N 3.48Å; S336-L339 PolarHBondContact O-N 2.86Å; A337-L339 PolarHBondContact O-N 2.86Å; L339-P342 WeakPolarHBondContact O-CD 3.04Å; L339-P342 WeakPolarHBondContact O-CG 3.32Å
340	A	93.3	Very high	91.1	Very high	8 Å²	8	55 Å²	55	7%	0.066	28%	0.275	C	S	.	.	H	α-helix	trans	-82.4	-14.9	179.8	0	0	0	0	0	114.2	S336 A337 T338 F343 W344 V390 A393	S336-A340 VanDerWaalsContact O-CB 3.26Å; S336-A340 WeakPolarHBondContact O-CB 3.27Å; S336-A340 PolarHBondContact O-N 2.81Å; A337-A340 PolarHBondContact O-N 3.16Å; T338-A340 VanDerWaalsContact C-N 3.27Å; T338-A340 PolarHBondContact O-N 3.39Å; A340-F343 WeakPolarHBondContact O-CB 3.16Å; A340-F343 PolarHBondContact O-N 2.93Å; A340-W344 PolarHBondContact O-N 2.73Å; A340-V390 HydrophobicContact CB-CB 4.25Å; A340-V390 HydrophobicContact CB-CG1 4.12Å; A340-V390 HydrophobicContact CB-CG2 4.17Å; A340-A393 HydrophobicContact CB-CB 3.83Å
341	I	90.4	Very high	90.9	Very high	56 Å²	56	60.2 Å²	60.2	29%	0.287	30%	0.297	S	S	.	.	H	α-helix	trans	-53.4	-52.3	177.2	-66.4	176.9	0	0	0	113.3	V189 A337 T338 F343 W344 Q345 A393 L397	V189-I341 HydrophobicContact CB-CD1 4.15Å; V189-I341 HydrophobicContact CG1-CD1 3.65Å; V189-I341 HydrophobicContact CG2-CD1 3.56Å; A337-I341 WeakPolarHBondContact O-CG1 3.45Å; A337-I341 PolarHBondContact O-N 3.22Å; T338-I341 PolarHBondContact O-N 3.24Å; I341-F343 VanDerWaalsContact C-N 3.26Å; I341-F343 PolarHBondContact O-N 2.69Å; I341-W344 PolarHBondContact O-N 3.01Å; I341-Q345 PolarHBondContact O-N 3.37Å; I341-A393 HydrophobicContact CG1-CB 4.37Å; I341-L397 HydrophobicContact CG2-CD1 4.19Å
342	P	90.3	Very high	90.7	Very high	85 Å²	85	58.6 Å²	58.6	55%	0.552	29%	0.292	S	S	*	.	H	α-helix	trans	-63	-34.3	179.2	23.8	-34.9	0	0	0	112.4	L339 Q345 W346	L339-P342 WeakPolarHBondContact O-CD 3.04Å; L339-P342 WeakPolarHBondContact O-CG 3.32Å; P342-Q345 PolarHBondContact O-N 3.05Å; P342-W346 WeakPolarHBondContact O-CB 3.04Å; P342-W346 PolarHBondContact O-N 3.27Å
343	F	92.5	Very high	90.4	Very high	99 Å²	99	58.2 Å²	58.2	43%	0.434	29%	0.287	S	S	.	.	H	α-helix	trans	-61.8	-47.4	174.5	166.5	-97.5	0	0	0	111.2	A340 I341 Q345 W346 F347	A340-F343 WeakPolarHBondContact O-CB 3.16Å; A340-F343 PolarHBondContact O-N 2.93Å; I341-F343 VanDerWaalsContact C-N 3.26Å; I341-F343 PolarHBondContact O-N 2.69Å; F343-Q345 VanDerWaalsContact C-N 3.34Å; F343-Q345 PolarHBondContact O-N 2.77Å; F343-W346 HydrophobicContact CE2-CZ3 4.46Å; F343-W346 PolarHBondContact O-N 3.27Å; F343-F347 WeakPolarHBondContact O-CB 3.2Å; F343-F347 PolarHBondContact O-N 2.86Å
344	W	90.9	Very high	90.1	Very high	9 Å²	9	60.9 Å²	60.9	3%	0.034	30%	0.298	C	S	.	.	H	α-helix	trans	-66.6	-36	176.8	-76	113.2	0	0	0	112.8	A340 I341 W346 F347 L348 V359 V390 A394 L397	A340-W344 PolarHBondContact O-N 2.73Å; I341-W344 PolarHBondContact O-N 3.01Å; W344-W346 VanDerWaalsContact C-N 3.35Å; W344-F347 HydrophobicContact CE3-CB 4.25Å; W344-F347 HydrophobicContact CE3-CD1 4.19Å; W344-F347 HydrophobicContact CE3-CG 4.36Å; W344-F347 HydrophobicContact CZ3-CD1 4Å; W344-F347 HydrophobicContact CZ3-CE1 4.43Å; W344-F347 HydrophobicContact CZ3-CG 4.35Å; W344-F347 PolarHBondContact O-N 3.06Å; W344-L348 WeakPolarHBondContact O-CB 3.37Å; W344-L348 WeakPolarHBondContact O-CD1 3.47Å; W344-L348 WeakPolarHBondContact O-CG 3.33Å; W344-L348 PolarHBondContact O-N 2.96Å; W344-V359 HydrophobicContact CH2-CG1 4.19Å; W344-V359 HydrophobicContact CZ3-CG1 4.46Å; W344-V390 HydrophobicContact CZ2-CG1 4.21Å; W344-V390 PolarHBondContact NE1-O 2.87Å; W344-A394 HydrophobicContact CD2-CB 3.72Å; W344-A394 HydrophobicContact CE3-CB 4.1Å; W344-A394 HydrophobicContact CG-CB 4.18Å; W344-A394 HydrophobicContact CH2-CB 4.2Å; W344-A394 HydrophobicContact CZ2-CB 3.81Å; W344-A394 HydrophobicContact CZ3-CB 4.33Å; W344-L397 HydrophobicContact CB-CD1 4.13Å
345	Q	89.1	Confident	90	Very high	94 Å²	94	65.7 Å²	65.7	44%	0.439	32%	0.321	S	S	.	.	H	α-helix	trans	-65.2	-40	175.7	-169.1	69.5	-49.3	0	0	112.2	I341 P342 F343 L348 T349 L397	I341-Q345 PolarHBondContact O-N 3.37Å; P342-Q345 PolarHBondContact O-N 3.05Å; F343-Q345 VanDerWaalsContact C-N 3.34Å; F343-Q345 PolarHBondContact O-N 2.77Å; Q345-L348 PolarHBondContact O-N 3.3Å; Q345-T349 WeakPolarHBondContact O-CG2 3.14Å; Q345-T349 PolarHBondContact O-N 3.48Å; Q345-T349 PolarHBondContact O-OG1 3.07Å; Q345-T349 VanDerWaalsContact O-OG1 3.08Å; Q345-L397 HydrophobicContact CB-CD1 4.41Å
346	W	91.1	Very high	89.8	Confident	124 Å²	124	61.3 Å²	61.3	47%	0.47	30%	0.299	S	S	.	.	H	α-helix	trans	-63.6	-42.5	171	172.7	85.7	0	0	0	111.8	P342 F343 W344 L348 T349 R350 F351	P342-W346 WeakPolarHBondContact O-CB 3.04Å; P342-W346 PolarHBondContact O-N 3.27Å; F343-W346 HydrophobicContact CE2-CZ3 4.46Å; F343-W346 PolarHBondContact O-N 3.27Å; W344-W346 VanDerWaalsContact C-N 3.35Å; W346-L348 VanDerWaalsContact C-N 3.34Å; W346-L348 PolarHBondContact O-N 2.87Å; W346-T349 PolarHBondContact O-N 2.68Å; W346-T349 PolarHBondContact O-OG1 2.88Å; W346-R350 WeakPolarHBondContact O-CB 3.43Å; W346-R350 PolarHBondContact O-N 2.86Å; W346-R350 VanDerWaalsContact O-N 3.14Å; W346-F351 HydrophobicContact CH2-CE2 4.3Å; W346-F351 HydrophobicContact CZ3-CE2 4.36Å
347	F	91.4	Very high	89.5	Confident	30 Å²	30	61.4 Å²	61.4	13%	0.132	30%	0.299	C	S	.	.	H	α-helix	trans	-63.4	-41.3	178.2	-167.7	-91.5	0	0	0	112	F343 W344 R350 F351 A356 V359	F343-F347 WeakPolarHBondContact O-CB 3.2Å; F343-F347 PolarHBondContact O-N 2.86Å; W344-F347 HydrophobicContact CE3-CB 4.25Å; W344-F347 HydrophobicContact CE3-CD1 4.19Å; W344-F347 HydrophobicContact CE3-CG 4.36Å; W344-F347 HydrophobicContact CZ3-CD1 4Å; W344-F347 HydrophobicContact CZ3-CE1 4.43Å; W344-F347 HydrophobicContact CZ3-CG 4.35Å; W344-F347 PolarHBondContact O-N 3.06Å; F347-R350 PolarHBondContact O-N 3.12Å; F347-F351 HydrophobicContact CD1-CB 4.44Å; F347-F351 HydrophobicContact CD1-CD2 4.38Å; F347-F351 AromaticContact CD2-CD2 3.47Å; F347-F351 HydrophobicContact CD2-CD2 3.47Å; F347-F351 VanDerWaalsContact CD2-CD2 3.47Å; F347-F351 AromaticContact CD2-CE2 3.81Å; F347-F351 HydrophobicContact CD2-CE2 3.81Å; F347-F351 HydrophobicContact CD2-CG 4.44Å; F347-F351 HydrophobicContact CE1-CB 4.06Å; F347-F351 HydrophobicContact CE1-CD2 4.31Å; F347-F351 HydrophobicContact CE1-CG 4.44Å; F347-F351 AromaticContact CE2-CD2 3.4Å; F347-F351 HydrophobicContact CE2-CD2 3.4Å; F347-F351 AromaticContact CE2-CE2 3.71Å; F347-F351 HydrophobicContact CE2-CE2 3.71Å; F347-F351 HydrophobicContact CE2-CG 4.04Å; F347-F351 AromaticContact CG-CD2 3.99Å; F347-F351 HydrophobicContact CG-CD2 3.99Å; F347-F351 HydrophobicContact CZ-CB 4.1Å; F347-F351 AromaticContact CZ-CD2 3.85Å; F347-F351 HydrophobicContact CZ-CD2 3.85Å; F347-F351 HydrophobicContact CZ-CG 4.04Å; F347-F351 PolarHBondContact O-N 3.16Å; F347-A356 HydrophobicContact CD1-CB 3.74Å; F347-A356 HydrophobicContact CE1-CB 4.08Å; F347-V359 HydrophobicContact CE1-CB 4.29Å; F347-V359 HydrophobicContact CE1-CG2 4.44Å; F347-V359 HydrophobicContact CZ-CB 4.35Å; F347-V359 HydrophobicContact CZ-CG1 4.3Å; F347-V359 HydrophobicContact CZ-CG2 4.25Å
348	L	87.3	Confident	89.5	Confident	7 Å²	7	63.4 Å²	63.4	4%	0.037	31%	0.305	C	S	.	.	H	α-helix	trans	-61	-44.7	178.1	-81.2	163.5	0	0	0	113.2	W344 Q345 W346 G352 K353 A356 L397 L398	W344-L348 WeakPolarHBondContact O-CB 3.37Å; W344-L348 WeakPolarHBondContact O-CD1 3.47Å; W344-L348 WeakPolarHBondContact O-CG 3.33Å; W344-L348 PolarHBondContact O-N 2.96Å; Q345-L348 PolarHBondContact O-N 3.3Å; W346-L348 VanDerWaalsContact C-N 3.34Å; W346-L348 PolarHBondContact O-N 2.87Å; L348-G352 CarbonylContact O-C 3.55Å; L348-G352 VanDerWaalsContact O-CA 3.32Å; L348-G352 WeakPolarHBondContact O-CA 3.49Å; L348-G352 PolarHBondContact O-N 3.31Å; L348-G352 VanDerWaalsContact O-N 3.16Å; L348-K353 HydrophobicContact CD2-CB 4.27Å; L348-K353 HydrophobicContact CD2-CG 4.14Å; L348-A356 HydrophobicContact CD2-CB 3.23Å; L348-A356 HydrophobicContact CG-CB 3.77Å; L348-L397 HydrophobicContact CD1-CD1 4.06Å; L348-L397 HydrophobicContact CD1-CD2 3.22Å; L348-L397 HydrophobicContact CD1-CG 4.21Å; L348-L398 HydrophobicContact CD2-CD2 3.66Å
349	T	85.8	Confident	89.6	Confident	114 Å²	114	65.3 Å²	65.3	70%	0.699	32%	0.316	S	S	*	.	H	α-helix	trans	-72.1	-29.9	-179.9	50.7	0	0	0	0	112.4	Q345 W346	Q345-T349 WeakPolarHBondContact O-CG2 3.14Å; Q345-T349 PolarHBondContact O-N 3.48Å; Q345-T349 PolarHBondContact O-OG1 3.07Å; Q345-T349 VanDerWaalsContact O-OG1 3.08Å; W346-T349 PolarHBondContact O-N 2.68Å; W346-T349 PolarHBondContact O-OG1 2.88Å
350	R	89.2	Confident	89.5	Confident	167 Å²	167	59.8 Å²	59.8	63%	0.63	29%	0.287	S	S	*	.	H	α-helix	trans	-88.1	-44.5	-177.3	-172.2	171.2	-174.6	138.8	0.4	114.5	W346 F347	W346-R350 WeakPolarHBondContact O-CB 3.43Å; W346-R350 PolarHBondContact O-N 2.86Å; W346-R350 VanDerWaalsContact O-N 3.14Å; F347-R350 PolarHBondContact O-N 3.12Å
351	F	86.6	Confident	89.3	Confident	109 Å²	109	59.5 Å²	59.5	48%	0.478	29%	0.285	S	S	.	.	H	α-helix	trans	-106.2	-4.6	-172.9	-64.4	-80.6	0	0	0	113.5	W346 F347	W346-F351 HydrophobicContact CH2-CE2 4.3Å; W346-F351 HydrophobicContact CZ3-CE2 4.36Å; F347-F351 HydrophobicContact CD1-CB 4.44Å; F347-F351 HydrophobicContact CD1-CD2 4.38Å; F347-F351 AromaticContact CD2-CD2 3.47Å; F347-F351 HydrophobicContact CD2-CD2 3.47Å; F347-F351 VanDerWaalsContact CD2-CD2 3.47Å; F347-F351 AromaticContact CD2-CE2 3.81Å; F347-F351 HydrophobicContact CD2-CE2 3.81Å; F347-F351 HydrophobicContact CD2-CG 4.44Å; F347-F351 HydrophobicContact CE1-CB 4.06Å; F347-F351 HydrophobicContact CE1-CD2 4.31Å; F347-F351 HydrophobicContact CE1-CG 4.44Å; F347-F351 AromaticContact CE2-CD2 3.4Å; F347-F351 HydrophobicContact CE2-CD2 3.4Å; F347-F351 AromaticContact CE2-CE2 3.71Å; F347-F351 HydrophobicContact CE2-CE2 3.71Å; F347-F351 HydrophobicContact CE2-CG 4.04Å; F347-F351 AromaticContact CG-CD2 3.99Å; F347-F351 HydrophobicContact CG-CD2 3.99Å; F347-F351 HydrophobicContact CZ-CB 4.1Å; F347-F351 AromaticContact CZ-CD2 3.85Å; F347-F351 HydrophobicContact CZ-CD2 3.85Å; F347-F351 HydrophobicContact CZ-CG 4.04Å; F347-F351 PolarHBondContact O-N 3.16Å
352	G	86.2	Confident	89.4	Confident	11 Å²	11	60.7 Å²	60.7	11%	0.113	29%	0.292	C	S	.	.			trans	86.7	158.8	179.5	0	0	0	0	0	113.7	L348 A356	L348-G352 CarbonylContact O-C 3.55Å; L348-G352 VanDerWaalsContact O-CA 3.32Å; L348-G352 WeakPolarHBondContact O-CA 3.49Å; L348-G352 PolarHBondContact O-N 3.31Å; L348-G352 VanDerWaalsContact O-N 3.16Å; G352-A356 WeakPolarHBondContact O-CB 3.1Å; G352-A356 PolarHBondContact O-N 2.85Å; G352-A356 VanDerWaalsContact O-N 3.15Å
353	K	85.6	Confident	89.5	Confident	32 Å²	32	58 Å²	58	14%	0.139	28%	0.275	C	S	.	.	H	α-helix	trans	-68.3	-39.3	-170.3	-59.5	-177.6	-174.8	-179.8	0	113.9	L348 A356 A357 S401 M402 D405	L348-K353 HydrophobicContact CD2-CB 4.27Å; L348-K353 HydrophobicContact CD2-CG 4.14Å; K353-A356 PolarHBondContact O-N 3.21Å; K353-A357 PolarHBondContact O-N 3.4Å; K353-S401 WeakPolarHBondContact CE-OG 3.31Å; K353-S401 PolarHBondContact NZ-O 3.01Å; K353-M402 HydrophobicContact CB-CG 4.04Å; K353-M402 HydrophobicContact CD-CG 4.27Å; K353-D405 WeakPolarHBondContact CD-OD2 3.4Å; K353-D405 WeakPolarHBondContact CE-OD2 3.45Å; K353-D405 IonicContact NZ-OD1 3.93Å; K353-D405 PolarHBondContact NZ-OD1 3.42Å; K353-D405 IonicContact NZ-OD2 3.64Å; K353-D405 PolarHBondContact NZ-OD2 2.96Å
354	K	86.4	Confident	89.4	Confident	66 Å²	66	53.5 Å²	53.5	29%	0.287	26%	0.255	S	S	.	.	H	α-helix	trans	-64.5	-46.6	-179.9	-169.2	169.4	-175.8	170.4	0	111.2	A357 Y358 Y487 Y489	K354-A357 WeakPolarHBondContact O-CB 3.41Å; K354-A357 PolarHBondContact O-N 3.32Å; K354-Y358 HydrophobicContact CD-CE2 4.49Å; K354-Y358 HydrophobicContact CG-CD2 4.14Å; K354-Y358 HydrophobicContact CG-CE2 3.82Å; K354-Y358 WeakPolarHBondContact O-CD2 3.5Å; K354-Y358 PolarHBondContact O-N 3.41Å; K354-Y358 VanDerWaalsContact O-N 3.15Å; K354-Y487 PolarHBondContact NZ-O 3Å; K354-Y487 VanDerWaalsContact NZ-O 3.1Å; K354-Y489 PolarHBondContact NZ-O 2.86Å
355	M	88.9	Confident	89.4	Confident	118 Å²	118	53.8 Å²	53.8	58%	0.581	26%	0.258	S	S	*	.	H	α-helix	trans	-64.5	-42.1	177.4	-72.6	-60.9	-174.7	0	0	112	A357 Y358 V359	M355-A357 VanDerWaalsContact C-N 3.26Å; M355-A357 PolarHBondContact O-N 3.41Å; M355-Y358 PolarHBondContact O-N 2.64Å; M355-V359 WeakPolarHBondContact O-CB 3.06Å; M355-V359 WeakPolarHBondContact O-CG2 3.34Å; M355-V359 PolarHBondContact O-N 3.31Å
356	A	90.1	Very high	89.5	Confident	0 Å²	0	52.5 Å²	52.5	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-59.4	-37.7	173.7	0	0	0	0	0	112.4	F347 L348 G352 K353 G360 L398	F347-A356 HydrophobicContact CD1-CB 3.74Å; F347-A356 HydrophobicContact CE1-CB 4.08Å; L348-A356 HydrophobicContact CD2-CB 3.23Å; L348-A356 HydrophobicContact CG-CB 3.77Å; G352-A356 WeakPolarHBondContact O-CB 3.1Å; G352-A356 PolarHBondContact O-N 2.85Å; G352-A356 VanDerWaalsContact O-N 3.15Å; K353-A356 PolarHBondContact O-N 3.21Å; A356-G360 WeakPolarHBondContact O-CA 3.42Å; A356-G360 PolarHBondContact O-N 2.99Å; A356-L398 HydrophobicContact CB-CD2 3.82Å
357	A	89	Confident	89.2	Confident	3 Å²	3	48.6 Å²	48.6	3%	0.025	25%	0.245	C	C	.	.	H	α-helix	trans	-62.9	-44.4	176	0	0	0	0	0	113.1	K353 K354 M355 S361 L398 M402	K353-A357 PolarHBondContact O-N 3.4Å; K354-A357 WeakPolarHBondContact O-CB 3.41Å; K354-A357 PolarHBondContact O-N 3.32Å; M355-A357 VanDerWaalsContact C-N 3.26Å; M355-A357 PolarHBondContact O-N 3.41Å; A357-S361 WeakPolarHBondContact O-CB 3.46Å; A357-S361 PolarHBondContact O-N 3.17Å; A357-S361 VanDerWaalsContact O-N 3.12Å; A357-S361 PolarHBondContact O-OG 2.71Å; A357-L398 HydrophobicContact CB-CD1 4.23Å; A357-L398 HydrophobicContact CB-CD2 4.08Å; A357-M402 HydrophobicContact CB-SD 4.12Å
358	Y	91.3	Very high	89	Confident	54 Å²	54	47.4 Å²	47.4	21%	0.212	24%	0.239	C	C	.	.	H	α-helix	trans	-65.4	-55.1	175.7	-80.9	-72.6	0	0	0	112.4	K354 M355 G360 S361 L362 L483 L486 Y487	K354-Y358 HydrophobicContact CD-CE2 4.49Å; K354-Y358 HydrophobicContact CG-CD2 4.14Å; K354-Y358 HydrophobicContact CG-CE2 3.82Å; K354-Y358 WeakPolarHBondContact O-CD2 3.5Å; K354-Y358 PolarHBondContact O-N 3.41Å; K354-Y358 VanDerWaalsContact O-N 3.15Å; M355-Y358 PolarHBondContact O-N 2.64Å; Y358-G360 VanDerWaalsContact C-N 3.34Å; Y358-G360 PolarHBondContact O-N 3.1Å; Y358-S361 PolarHBondContact O-N 3Å; Y358-L362 WeakPolarHBondContact O-CB 3.47Å; Y358-L362 PolarHBondContact O-N 2.91Å; Y358-L483 HydrophobicContact CD1-CB 4.33Å; Y358-L483 HydrophobicContact CD1-CD1 4.28Å; Y358-L483 HydrophobicContact CD1-CD2 3.7Å; Y358-L483 HydrophobicContact CD1-CG 4.32Å; Y358-L483 HydrophobicContact CE1-CB 3.94Å; Y358-L483 HydrophobicContact CE1-CD2 3.9Å; Y358-L483 HydrophobicContact CE1-CG 4.39Å; Y358-L483 HydrophobicContact CG-CD2 4.38Å; Y358-L483 PolarHBondContact OH-O 3.47Å; Y358-L486 VanDerWaalsContact OH-C 3.29Å; Y358-Y487 WeakPolarHBondContact OH-CA 3.01Å; Y358-Y487 WeakPolarHBondContact OH-CB 3.32Å; Y358-Y487 PolarHBondContact OH-N 3.36Å
359	V	92.9	Very high	89.1	Confident	69 Å²	69	50.9 Å²	50.9	42%	0.418	26%	0.257	S	S	.	.	H	α-helix	trans	-64.1	-42	-175.9	177	0	0	0	0	110.6	W344 F347 M355 S363	W344-V359 HydrophobicContact CH2-CG1 4.19Å; W344-V359 HydrophobicContact CZ3-CG1 4.46Å; F347-V359 HydrophobicContact CE1-CB 4.29Å; F347-V359 HydrophobicContact CE1-CG2 4.44Å; F347-V359 HydrophobicContact CZ-CB 4.35Å; F347-V359 HydrophobicContact CZ-CG1 4.3Å; F347-V359 HydrophobicContact CZ-CG2 4.25Å; M355-V359 WeakPolarHBondContact O-CB 3.06Å; M355-V359 WeakPolarHBondContact O-CG2 3.34Å; M355-V359 PolarHBondContact O-N 3.31Å; V359-S363 VanDerWaalsContact O-CB 3.23Å; V359-S363 WeakPolarHBondContact O-CB 3.45Å; V359-S363 PolarHBondContact O-N 3.11Å; V359-S363 PolarHBondContact O-OG 3.27Å
360	G	90.9	Very high	89.1	Confident	0 Å²	0	48.8 Å²	48.8	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-60.4	-54	177	0	0	0	0	0	112.8	A356 Y358 S363	A356-G360 WeakPolarHBondContact O-CA 3.42Å; A356-G360 PolarHBondContact O-N 2.99Å; Y358-G360 VanDerWaalsContact C-N 3.34Å; Y358-G360 PolarHBondContact O-N 3.1Å; G360-S363 PolarHBondContact O-N 3.2Å; G360-S363 PolarHBondContact O-OG 2.95Å
361	S	89.9	Confident	88.7	Confident	2 Å²	2	41.7 Å²	41.7	1%	0.014	22%	0.216	C	C	.	.	H	α-helix	trans	-68.5	-38.7	-178.3	-48.2	0	0	0	0	112.1	A357 Y358 S363 A364	A357-S361 WeakPolarHBondContact O-CB 3.46Å; A357-S361 PolarHBondContact O-N 3.17Å; A357-S361 VanDerWaalsContact O-N 3.12Å; A357-S361 PolarHBondContact O-OG 2.71Å; Y358-S361 PolarHBondContact O-N 3Å; S361-S363 VanDerWaalsContact C-N 3.32Å; S361-S363 PolarHBondContact O-N 3.35Å; S361-A364 WeakPolarHBondContact O-CB 3.34Å; S361-A364 PolarHBondContact O-N 3.26Å
362	L	92.2	Very high	88.6	Confident	82 Å²	82	38.5 Å²	38.5	43%	0.429	21%	0.205	S	C	.	.	H	α-helix	trans	-71.9	-27.7	179.9	-160.3	70.3	0	0	0	112.2	Y358 A364 V365 P366 F480 L483	Y358-L362 WeakPolarHBondContact O-CB 3.47Å; Y358-L362 PolarHBondContact O-N 2.91Å; L362-A364 PolarHBondContact O-N 2.95Å; L362-V365 HydrophobicContact CD1-CG2 4.25Å; L362-V365 WeakPolarHBondContact O-CB 3.32Å; L362-V365 PolarHBondContact O-N 3.45Å; L362-P366 VanDerWaalsContact O-CD 3.27Å; L362-P366 WeakPolarHBondContact O-CD 3.21Å; L362-F480 HydrophobicContact CD1-CE1 3.76Å; L362-F480 HydrophobicContact CD1-CZ 4.05Å; L362-L483 HydrophobicContact CB-CD1 4.44Å; L362-L483 HydrophobicContact CD1-CD1 4.22Å
363	S	92	Very high	88.3	Confident	29 Å²	29	42.6 Å²	42.6	20%	0.203	23%	0.231	C	C	.	.	H	α-helix	trans	-61.6	-24.3	173.3	74.6	0	0	0	0	112.9	V359 G360 S361 P366 F367 A391	V359-S363 VanDerWaalsContact O-CB 3.23Å; V359-S363 WeakPolarHBondContact O-CB 3.45Å; V359-S363 PolarHBondContact O-N 3.11Å; V359-S363 PolarHBondContact O-OG 3.27Å; G360-S363 PolarHBondContact O-N 3.2Å; G360-S363 PolarHBondContact O-OG 2.95Å; S361-S363 VanDerWaalsContact C-N 3.32Å; S361-S363 PolarHBondContact O-N 3.35Å; S363-P366 VanDerWaalsContact O-CD 3.3Å; S363-P366 WeakPolarHBondContact O-CD 3.48Å; S363-P366 WeakPolarHBondContact O-CG 3.5Å; S363-F367 WeakPolarHBondContact O-CD2 3.42Å; S363-F367 WeakPolarHBondContact O-CE2 3.14Å; S363-A391 WeakPolarHBondContact OG-CB 3.29Å
364	A	90.1	Very high	87.6	Confident	3 Å²	3	42.1 Å²	42.1	3%	0.025	23%	0.231	C	C	.	.	H	α-helix	trans	-70.6	-31.1	177.1	0	0	0	0	0	113.5	F305 S361 L362 F367 M368 A391 I479	F305-A364 HydrophobicContact CE1-CB 4.03Å; F305-A364 HydrophobicContact CZ-CB 3.72Å; S361-A364 WeakPolarHBondContact O-CB 3.34Å; S361-A364 PolarHBondContact O-N 3.26Å; L362-A364 PolarHBondContact O-N 2.95Å; A364-F367 PolarHBondContact O-N 3.46Å; A364-M368 HydrophobicContact CB-CE 4.37Å; A364-M368 WeakPolarHBondContact O-CG 3.29Å; A364-M368 PolarHBondContact O-N 2.82Å; A364-A391 HydrophobicContact CB-CB 3.78Å; A364-I479 HydrophobicContact CB-CD1 4.17Å
365	V	91.7	Very high	86.6	Confident	15 Å²	15	43.2 Å²	43.2	9%	0.091	24%	0.244	C	C	.	.	H	α-helix	trans	-58.6	-51.9	-174.6	176.8	0	0	0	0	113.5	L362 F367 M368 I369 V476 I479 F480	L362-V365 HydrophobicContact CD1-CG2 4.25Å; L362-V365 WeakPolarHBondContact O-CB 3.32Å; L362-V365 PolarHBondContact O-N 3.45Å; V365-F367 PolarHBondContact O-N 2.93Å; V365-M368 PolarHBondContact O-N 3.5Å; V365-I369 HydrophobicContact CG1-CD1 3.84Å; V365-I369 WeakPolarHBondContact O-CG1 3.36Å; V365-I369 PolarHBondContact O-N 3.04Å; V365-V476 HydrophobicContact CG1-CG1 3.98Å; V365-V476 HydrophobicContact CG1-CG2 4.1Å; V365-V476 HydrophobicContact CG2-CG1 4.47Å; V365-V476 HydrophobicContact CG2-CG2 4.49Å; V365-I479 HydrophobicContact CG2-CG2 4.32Å; V365-F480 HydrophobicContact CG1-CE2 4.49Å
366	P	90.3	Very high	85.7	Confident	68 Å²	68	44.8 Å²	44.8	44%	0.442	25%	0.248	S	C	.	.	H	α-helix	trans	-60.6	-34.3	178.6	23.9	-34.9	0	0	0	111.9	L362 S363 I369 M370	L362-P366 VanDerWaalsContact O-CD 3.27Å; L362-P366 WeakPolarHBondContact O-CD 3.21Å; S363-P366 VanDerWaalsContact O-CD 3.3Å; S363-P366 WeakPolarHBondContact O-CD 3.48Å; S363-P366 WeakPolarHBondContact O-CG 3.5Å; P366-I369 PolarHBondContact O-N 3.09Å; P366-M370 WeakPolarHBondContact O-CB 3.42Å; P366-M370 PolarHBondContact O-N 3.14Å
367	F	85	Confident	85.3	Confident	41 Å²	41	48.8 Å²	48.8	18%	0.18	27%	0.269	C	S	.	.	H	α-helix	trans	-68.7	-45.6	177.4	-52.7	-45.9	0	0	0	111.7	S363 A364 V365 I369 M370 V371 V384 A387 A391	S363-F367 WeakPolarHBondContact O-CD2 3.42Å; S363-F367 WeakPolarHBondContact O-CE2 3.14Å; A364-F367 PolarHBondContact O-N 3.46Å; V365-F367 PolarHBondContact O-N 2.93Å; F367-I369 VanDerWaalsContact C-N 3.26Å; F367-I369 PolarHBondContact O-N 3.45Å; F367-M370 PolarHBondContact O-N 3.33Å; F367-V371 VanDerWaalsContact O-CG2 3.3Å; F367-V371 WeakPolarHBondContact O-CG2 3.28Å; F367-V371 PolarHBondContact O-N 3.41Å; F367-V384 HydrophobicContact CB-CG1 4.35Å; F367-A387 HydrophobicContact CD1-CB 3.63Å; F367-A387 HydrophobicContact CD2-CB 4.47Å; F367-A387 WeakPolarHBondContact CD2-O 3.32Å; F367-A387 HydrophobicContact CE1-CB 3.1Å; F367-A387 VanDerWaalsContact CE2-C 3.43Å; F367-A387 HydrophobicContact CE2-CB 4.01Å; F367-A387 WeakPolarHBondContact CE2-O 3.45Å; F367-A387 HydrophobicContact CG-CB 4.32Å; F367-A387 HydrophobicContact CZ-CB 3.32Å; F367-A391 HydrophobicContact CD2-CB 4.12Å; F367-A391 HydrophobicContact CE2-CB 4.19Å
368	M	88.2	Confident	84.9	Confident	5 Å²	5	51.8 Å²	51.8	3%	0.025	29%	0.285	C	S	.	.	H	α-helix	trans	-58.4	-37.6	175.7	-73.3	176.5	176.9	0	0	112.4	L308 A364 V365 S472 P475 V476 I479	L308-M368 HydrophobicContact CB-CE 4.42Å; L308-M368 HydrophobicContact CD2-CE 3.85Å; A364-M368 HydrophobicContact CB-CE 4.37Å; A364-M368 WeakPolarHBondContact O-CG 3.29Å; A364-M368 PolarHBondContact O-N 2.82Å; V365-M368 PolarHBondContact O-N 3.5Å; M368-S472 VanDerWaalsContact C-OG 3.26Å; M368-S472 VanDerWaalsContact O-CB 3.29Å; M368-S472 WeakPolarHBondContact O-CB 3.2Å; M368-S472 PolarHBondContact O-OG 2.94Å; M368-P475 HydrophobicContact CE-CB 3.67Å; M368-P475 HydrophobicContact SD-CB 3.57Å; M368-P475 VanDerWaalsContact SD-CB 3.57Å; M368-V476 HydrophobicContact CB-CG2 4Å; M368-V476 HydrophobicContact SD-CG2 3.95Å; M368-I479 HydrophobicContact CE-CD1 3.86Å; M368-I479 HydrophobicContact SD-CD1 4Å
369	I	89.3	Confident	84.6	Confident	80 Å²	80	55.5 Å²	55.5	41%	0.41	31%	0.307	S	S	.	.	H	α-helix	trans	-71.7	-46.5	175.5	-64.1	168.2	0	0	0	110.3	V365 P366 F367 V371 V372 C373	V365-I369 HydrophobicContact CG1-CD1 3.84Å; V365-I369 WeakPolarHBondContact O-CG1 3.36Å; V365-I369 PolarHBondContact O-N 3.04Å; P366-I369 PolarHBondContact O-N 3.09Å; F367-I369 VanDerWaalsContact C-N 3.26Å; F367-I369 PolarHBondContact O-N 3.45Å; I369-V371 VanDerWaalsContact C-N 3.34Å; I369-V371 PolarHBondContact O-N 3.35Å; I369-V372 PolarHBondContact O-N 3.19Å; I369-V372 VanDerWaalsContact O-N 3.11Å; I369-C373 PolarHBondContact O-N 3.25Å; I369-C373 PolarHBondContact O-SG 3.31Å; I369-C373 VanDerWaalsContact O-SG 3.4Å
370	M	85.7	Confident	84.2	Confident	71 Å²	71	54.8 Å²	54.8	35%	0.35	30%	0.302	S	S	.	.	H	α-helix	trans	-64.2	-36.9	-176.7	-161.8	159.6	92.8	0	0	112.3	P366 F367 V372 C373 V374 V384	P366-M370 WeakPolarHBondContact O-CB 3.42Å; P366-M370 PolarHBondContact O-N 3.14Å; F367-M370 PolarHBondContact O-N 3.33Å; M370-V372 PolarHBondContact O-N 2.88Å; M370-C373 PolarHBondContact O-N 3.31Å; M370-V374 HydrophobicContact CG-CG2 3.58Å; M370-V374 VanDerWaalsContact O-CB 3.28Å; M370-V374 WeakPolarHBondContact O-CB 3.45Å; M370-V374 WeakPolarHBondContact O-CG2 3.29Å; M370-V374 PolarHBondContact O-N 3.02Å; M370-V384 HydrophobicContact CB-CG1 4.3Å; M370-V384 HydrophobicContact CE-CB 3.95Å; M370-V384 HydrophobicContact CE-CG1 4.11Å; M370-V384 HydrophobicContact CE-CG2 3.17Å; M370-V384 HydrophobicContact CG-CG2 4.03Å; M370-V384 HydrophobicContact SD-CG2 4.39Å
371	V	81.3	Confident	83.9	Confident	18 Å²	18	55.3 Å²	55.3	11%	0.109	31%	0.306	C	S	.	.	H	α-helix	trans	-56.4	-32.8	174.7	166.3	0	0	0	0	112.4	F312 F315 F367 I369 V384 V471	F312-V371 HydrophobicContact CE2-CG1 4.42Å; F315-V371 HydrophobicContact CD1-CG1 4.01Å; F315-V371 HydrophobicContact CE1-CG1 3.33Å; F315-V371 HydrophobicContact CZ-CG1 4.01Å; F367-V371 VanDerWaalsContact O-CG2 3.3Å; F367-V371 WeakPolarHBondContact O-CG2 3.28Å; F367-V371 PolarHBondContact O-N 3.41Å; I369-V371 VanDerWaalsContact C-N 3.34Å; I369-V371 PolarHBondContact O-N 3.35Å; V371-V384 HydrophobicContact CG2-CG1 3.48Å; V371-V384 VanDerWaalsContact CG2-CG1 3.48Å; V371-V471 HydrophobicContact CG1-CG1 4.26Å
372	V	82.8	Confident	83.9	Confident	42 Å²	42	58.5 Å²	58.5	26%	0.255	32%	0.318	S	S	.	.	H	α-helix	trans	-88.5	-35.1	179.7	174.9	0	0	0	0	112.4	F315 I369 M370 K468	F315-V372 HydrophobicContact CZ-CG2 4.27Å; I369-V372 PolarHBondContact O-N 3.19Å; I369-V372 VanDerWaalsContact O-N 3.11Å; M370-V372 PolarHBondContact O-N 2.88Å; V372-K468 HydrophobicContact CG1-CB 4.11Å; V372-K468 HydrophobicContact CG1-CD 3.89Å; V372-K468 HydrophobicContact CG1-CG 3.79Å; V372-K468 HydrophobicContact CG2-CB 4.37Å; V372-K468 HydrophobicContact CG2-CG 4.3Å
373	C	80.5	Confident	83.7	Confident	96 Å²	96	59.7 Å²	59.7	65%	0.649	32%	0.323	S	S	*	.	H	α-helix	trans	-80.6	-22.8	-177.4	-65.4	0	0	0	0	113.8	I369 M370	I369-C373 PolarHBondContact O-N 3.25Å; I369-C373 PolarHBondContact O-SG 3.31Å; I369-C373 VanDerWaalsContact O-SG 3.4Å; M370-C373 PolarHBondContact O-N 3.31Å
374	V	70.9	Confident	83.5	Confident	23 Å²	23	58.4 Å²	58.4	14%	0.139	31%	0.314	C	S	.	.	S	Bend	trans	-71.5	124.9	-174.8	164.2	0	0	0	0	110.7	M370 V380 V384	M370-V374 HydrophobicContact CG-CG2 3.58Å; M370-V374 VanDerWaalsContact O-CB 3.28Å; M370-V374 WeakPolarHBondContact O-CB 3.45Å; M370-V374 WeakPolarHBondContact O-CG2 3.29Å; M370-V374 PolarHBondContact O-N 3.02Å; V374-V380 HydrophobicContact CB-CG1 4.28Å; V374-V380 HydrophobicContact CG1-CB 3.82Å; V374-V380 HydrophobicContact CG1-CG1 3.55Å; V374-V380 HydrophobicContact CG2-CG1 3.6Å; V374-V384 HydrophobicContact CG2-CG2 4.39Å
375	P	65	Low	83.4	Confident	88 Å²	88	58.3 Å²	58.3	57%	0.571	31%	0.313	S	S	*	.			trans	-62.9	160.7	171.1	27.4	-33.4	0	0	0	109.9	N377	P375-N377 PolarHBondContact O-N 3.47Å
376	K	70.7	Confident	83.4	Confident	151 Å²	151	63 Å²	63	66%	0.657	33%	0.333	S	S	*	.	S	Bend	trans	-57.1	65.1	-174.5	-61.7	-178.5	179	-179.1	0	114.7	F322	F322-K376 HydrophobicContact CZ-CB 4.24Å
377	N	81.3	Confident	83.4	Confident	84 Å²	84	60.8 Å²	60.8	45%	0.449	32%	0.32	S	S	.	.			trans	-117.2	111.4	-178.1	-75.2	-26.3	0	0	0	108.1	P375 I379 V380 T381	P375-N377 PolarHBondContact O-N 3.47Å; N377-I379 PolarHBondContact O-N 2.68Å; N377-V380 HydrophobicContact CB-CB 4.18Å; N377-V380 HydrophobicContact CB-CG2 3.94Å; N377-V380 PolarHBondContact O-N 3.06Å; N377-T381 PolarHBondContact O-N 2.93Å; N377-T381 VanDerWaalsContact O-N 3.1Å; N377-T381 PolarHBondContact O-OG1 2.92Å
378	L	81.1	Confident	83.6	Confident	67 Å²	67	59.3 Å²	59.3	35%	0.351	32%	0.315	S	S	.	.	H	α-helix	trans	-58.6	-45.6	-177.7	-74.1	170	0	0	0	112.1	F322 D325 V380 T381 Y382	F322-L378 HydrophobicContact CD1-CD2 3.37Å; F322-L378 HydrophobicContact CD1-CG 4.17Å; F322-L378 HydrophobicContact CD2-CD2 4.04Å; F322-L378 HydrophobicContact CE1-CD2 3.33Å; F322-L378 HydrophobicContact CE1-CG 3.66Å; F322-L378 HydrophobicContact CE2-CD2 4.01Å; F322-L378 HydrophobicContact CG-CD2 3.75Å; F322-L378 HydrophobicContact CZ-CD2 3.66Å; F322-L378 HydrophobicContact CZ-CG 3.94Å; D325-L378 HydrophobicContact CB-CD2 4.21Å; L378-V380 PolarHBondContact O-N 3.18Å; L378-T381 WeakPolarHBondContact O-CB 3.49Å; L378-T381 PolarHBondContact O-N 3.08Å; L378-Y382 WeakPolarHBondContact O-CD2 3.43Å; L378-Y382 PolarHBondContact O-N 3.49Å
379	I	85.1	Confident	83.7	Confident	131 Å²	131	59.1 Å²	59.1	67%	0.672	31%	0.314	S	S	*	.	H	α-helix	trans	-61.3	-46.8	-177.1	-60.1	173.1	0	0	0	111.2	N377 T381 Y382 I383	N377-I379 PolarHBondContact O-N 2.68Å; I379-T381 VanDerWaalsContact C-N 3.29Å; I379-T381 PolarHBondContact O-N 2.89Å; I379-Y382 PolarHBondContact O-N 3.37Å; I379-I383 HydrophobicContact CG2-CD1 4.2Å; I379-I383 WeakPolarHBondContact O-CG1 3.28Å; I379-I383 PolarHBondContact O-N 3.13Å; I379-I383 VanDerWaalsContact O-N 3.12Å
380	V	85.2	Confident	83.9	Confident	54 Å²	54	57.1 Å²	57.1	33%	0.327	31%	0.305	S	S	.	.	H	α-helix	trans	-62.7	-41.8	178.8	-175.9	0	0	0	0	109.8	V374 N377 L378 Y382 I383 V384	V374-V380 HydrophobicContact CB-CG1 4.28Å; V374-V380 HydrophobicContact CG1-CB 3.82Å; V374-V380 HydrophobicContact CG1-CG1 3.55Å; V374-V380 HydrophobicContact CG2-CG1 3.6Å; N377-V380 HydrophobicContact CB-CB 4.18Å; N377-V380 HydrophobicContact CB-CG2 3.94Å; N377-V380 PolarHBondContact O-N 3.06Å; L378-V380 PolarHBondContact O-N 3.18Å; V380-Y382 VanDerWaalsContact C-N 3.33Å; V380-Y382 PolarHBondContact O-N 3.23Å; V380-I383 PolarHBondContact O-N 3.1Å; V380-I383 VanDerWaalsContact O-N 3.17Å; V380-V384 HydrophobicContact CG1-CG2 4.16Å; V380-V384 WeakPolarHBondContact O-CG2 3.2Å; V380-V384 PolarHBondContact O-N 3.32Å
381	T	84.1	Confident	84.1	Confident	12 Å²	12	53.7 Å²	53.7	7%	0.074	29%	0.289	C	S	.	.	H	α-helix	trans	-60.2	-40.8	177.6	-51.5	0	0	0	0	112.1	L320 F322 I329 N377 L378 I379 V384 S385	L320-T381 HydrophobicContact CD1-CG2 4.5Å; F322-T381 HydrophobicContact CE2-CG2 4.46Å; I329-T381 HydrophobicContact CD1-CG2 3.76Å; N377-T381 PolarHBondContact O-N 2.93Å; N377-T381 VanDerWaalsContact O-N 3.1Å; N377-T381 PolarHBondContact O-OG1 2.92Å; L378-T381 WeakPolarHBondContact O-CB 3.49Å; L378-T381 PolarHBondContact O-N 3.08Å; I379-T381 VanDerWaalsContact C-N 3.29Å; I379-T381 PolarHBondContact O-N 2.89Å; T381-V384 PolarHBondContact O-N 2.59Å; T381-S385 VanDerWaalsContact O-CB 3.28Å; T381-S385 WeakPolarHBondContact O-CB 3.41Å; T381-S385 PolarHBondContact O-N 2.84Å; T381-S385 PolarHBondContact O-OG 3.18Å
382	Y	88.4	Confident	84.5	Confident	69 Å²	69	53.5 Å²	53.5	27%	0.271	29%	0.287	S	S	.	.	H	α-helix	trans	-63.8	-42	174.6	-82.2	-67.4	0	0	0	112.9	N328 I329 V332 L378 I379 V380 S385 F386	N328-Y382 HydrophobicContact CB-CE1 4.27Å; N328-Y382 VanDerWaalsContact CB-OH 3.29Å; N328-Y382 WeakPolarHBondContact CB-OH 3.31Å; I329-Y382 HydrophobicContact CG1-CD1 4.42Å; I329-Y382 HydrophobicContact CG1-CE1 4Å; V332-Y382 HydrophobicContact CB-CD1 4.44Å; V332-Y382 HydrophobicContact CG2-CD1 3.91Å; V332-Y382 HydrophobicContact CG2-CE1 4.03Å; L378-Y382 WeakPolarHBondContact O-CD2 3.43Å; L378-Y382 PolarHBondContact O-N 3.49Å; I379-Y382 PolarHBondContact O-N 3.37Å; V380-Y382 VanDerWaalsContact C-N 3.33Å; V380-Y382 PolarHBondContact O-N 3.23Å; Y382-S385 PolarHBondContact O-N 3.1Å; Y382-F386 PolarHBondContact O-N 3.42Å
383	I	89.3	Confident	84.9	Confident	106 Å²	106	51.7 Å²	51.7	54%	0.544	28%	0.277	S	S	.	.	H	α-helix	trans	-63.1	-45.1	176.7	-65.4	168.4	0	0	0	110.4	I379 V380 S385 F386 A387	I379-I383 HydrophobicContact CG2-CD1 4.2Å; I379-I383 WeakPolarHBondContact O-CG1 3.28Å; I379-I383 PolarHBondContact O-N 3.13Å; I379-I383 VanDerWaalsContact O-N 3.12Å; V380-I383 PolarHBondContact O-N 3.1Å; V380-I383 VanDerWaalsContact O-N 3.17Å; I383-S385 VanDerWaalsContact C-N 3.25Å; I383-S385 PolarHBondContact O-N 3.42Å; I383-F386 PolarHBondContact O-N 3.41Å; I383-A387 WeakPolarHBondContact O-CB 3.2Å; I383-A387 PolarHBondContact O-N 3.25Å; I383-A387 VanDerWaalsContact O-N 3.11Å
384	V	88.2	Confident	85.3	Confident	2 Å²	2	47.1 Å²	47.1	1%	0.012	25%	0.246	C	C	.	.	H	α-helix	trans	-60.1	-40.6	176.8	-173	0	0	0	0	110.6	F367 M370 V371 V374 V380 T381 A387 S388	F367-V384 HydrophobicContact CB-CG1 4.35Å; M370-V384 HydrophobicContact CB-CG1 4.3Å; M370-V384 HydrophobicContact CE-CB 3.95Å; M370-V384 HydrophobicContact CE-CG1 4.11Å; M370-V384 HydrophobicContact CE-CG2 3.17Å; M370-V384 HydrophobicContact CG-CG2 4.03Å; M370-V384 HydrophobicContact SD-CG2 4.39Å; V371-V384 HydrophobicContact CG2-CG1 3.48Å; V371-V384 VanDerWaalsContact CG2-CG1 3.48Å; V374-V384 HydrophobicContact CG2-CG2 4.39Å; V380-V384 HydrophobicContact CG1-CG2 4.16Å; V380-V384 WeakPolarHBondContact O-CG2 3.2Å; V380-V384 PolarHBondContact O-N 3.32Å; T381-V384 PolarHBondContact O-N 2.59Å; V384-A387 PolarHBondContact O-N 2.98Å; V384-S388 WeakPolarHBondContact O-CB 3.44Å; V384-S388 PolarHBondContact O-N 2.92Å
385	S	87.9	Confident	86.1	Confident	1 Å²	1	46.9 Å²	46.9	1%	0.007	25%	0.246	C	C	.	.	H	α-helix	trans	-69.8	-41.2	-176.9	-61.1	0	0	0	0	112.3	I329 I333 T381 Y382 I383 A387 S388 G389	I329-S385 WeakPolarHBondContact CG2-OG 3.48Å; I333-S385 WeakPolarHBondContact CG1-O 3.49Å; T381-S385 VanDerWaalsContact O-CB 3.28Å; T381-S385 WeakPolarHBondContact O-CB 3.41Å; T381-S385 PolarHBondContact O-N 2.84Å; T381-S385 PolarHBondContact O-OG 3.18Å; Y382-S385 PolarHBondContact O-N 3.1Å; I383-S385 VanDerWaalsContact C-N 3.25Å; I383-S385 PolarHBondContact O-N 3.42Å; S385-A387 VanDerWaalsContact C-N 3.29Å; S385-A387 PolarHBondContact O-N 3.39Å; S385-S388 PolarHBondContact O-N 3.37Å; S385-G389 PolarHBondContact O-N 3Å
386	F	91.4	Very high	86.9	Confident	115 Å²	115	48 Å²	48	50%	0.504	24%	0.242	S	C	.	.	H	α-helix	trans	-57.8	-45.8	171.2	179.6	-90.9	0	0	0	111.2	V332 S336 Y382 I383 G389 V390	V332-F386 HydrophobicContact CG1-CB 4.13Å; S336-F386 VanDerWaalsContact CB-CD2 3.49Å; S336-F386 WeakPolarHBondContact CB-O 3.28Å; S336-F386 PolarHBondContact OG-O 2.67Å; Y382-F386 PolarHBondContact O-N 3.42Å; I383-F386 PolarHBondContact O-N 3.41Å; F386-G389 PolarHBondContact O-N 2.96Å; F386-V390 HydrophobicContact CE1-CG2 4.48Å; F386-V390 PolarHBondContact O-N 3.25Å
387	A	90.4	Very high	87.6	Confident	20 Å²	20	42.2 Å²	42.2	17%	0.165	22%	0.219	C	C	.	.	H	α-helix	trans	-69.2	-37	-178.8	0	0	0	0	0	112	F367 I383 V384 S385 G389 V390 A391	F367-A387 HydrophobicContact CD1-CB 3.63Å; F367-A387 HydrophobicContact CD2-CB 4.47Å; F367-A387 WeakPolarHBondContact CD2-O 3.32Å; F367-A387 HydrophobicContact CE1-CB 3.1Å; F367-A387 VanDerWaalsContact CE2-C 3.43Å; F367-A387 HydrophobicContact CE2-CB 4.01Å; F367-A387 WeakPolarHBondContact CE2-O 3.45Å; F367-A387 HydrophobicContact CG-CB 4.32Å; F367-A387 HydrophobicContact CZ-CB 3.32Å; I383-A387 WeakPolarHBondContact O-CB 3.2Å; I383-A387 PolarHBondContact O-N 3.25Å; I383-A387 VanDerWaalsContact O-N 3.11Å; V384-A387 PolarHBondContact O-N 2.98Å; S385-A387 VanDerWaalsContact C-N 3.29Å; S385-A387 PolarHBondContact O-N 3.39Å; A387-G389 VanDerWaalsContact C-N 3.33Å; A387-G389 PolarHBondContact O-N 3.1Å; A387-V390 WeakPolarHBondContact O-CB 3.22Å; A387-V390 PolarHBondContact O-N 3.17Å; A387-A391 PolarHBondContact O-N 2.87Å
388	S	89.4	Confident	87.8	Confident	11 Å²	11	38.3 Å²	38.3	8%	0.077	20%	0.198	C	C	.	.	H	α-helix	trans	-60.5	-39.4	171.9	-172.7	0	0	0	0	112.6	V384 S385 V390 A391 V392	V384-S388 WeakPolarHBondContact O-CB 3.44Å; V384-S388 PolarHBondContact O-N 2.92Å; S385-S388 PolarHBondContact O-N 3.37Å; S388-V390 VanDerWaalsContact C-N 3.29Å; S388-V390 PolarHBondContact O-N 3.03Å; S388-A391 PolarHBondContact O-N 3.17Å; S388-A391 VanDerWaalsContact O-N 3.12Å; S388-V392 WeakPolarHBondContact O-CG2 2.92Å; S388-V392 PolarHBondContact O-N 3.4Å
389	G	90.4	Very high	87.9	Confident	0 Å²	0	35.3 Å²	35.3	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-62.1	-36.8	177.3	0	0	0	0	0	112.6	I333 S336 A337 S385 F386 A387 A391 V392 A393	I333-G389 WeakPolarHBondContact O-CA 3.46Å; S336-G389 WeakPolarHBondContact OG-CA 3.02Å; A337-G389 WeakPolarHBondContact CA-O 2.95Å; A337-G389 VanDerWaalsContact CB-O 3.26Å; A337-G389 WeakPolarHBondContact CB-O 3.13Å; S385-G389 PolarHBondContact O-N 3Å; F386-G389 PolarHBondContact O-N 2.96Å; A387-G389 VanDerWaalsContact C-N 3.33Å; A387-G389 PolarHBondContact O-N 3.1Å; G389-A391 VanDerWaalsContact C-N 3.3Å; G389-A391 PolarHBondContact O-N 3.44Å; G389-V392 PolarHBondContact O-N 3.32Å; G389-A393 PolarHBondContact O-N 2.63Å
390	V	91.9	Very high	87.8	Confident	38 Å²	38	34.2 Å²	34.2	23%	0.23	17%	0.17	C	C	.	.	H	α-helix	trans	-58	-43.6	172.8	-178.4	0	0	0	0	111	A340 W344 F386 A387 S388 A393	A340-V390 HydrophobicContact CB-CB 4.25Å; A340-V390 HydrophobicContact CB-CG1 4.12Å; A340-V390 HydrophobicContact CB-CG2 4.17Å; W344-V390 HydrophobicContact CZ2-CG1 4.21Å; W344-V390 PolarHBondContact NE1-O 2.87Å; F386-V390 HydrophobicContact CE1-CG2 4.48Å; F386-V390 PolarHBondContact O-N 3.25Å; A387-V390 WeakPolarHBondContact O-CB 3.22Å; A387-V390 PolarHBondContact O-N 3.17Å; S388-V390 VanDerWaalsContact C-N 3.29Å; S388-V390 PolarHBondContact O-N 3.03Å; V390-A393 PolarHBondContact O-N 3.32Å
391	A	91.1	Very high	87.8	Confident	0 Å²	0	32.8 Å²	32.8	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-68.5	-39.5	178.3	0	0	0	0	0	112.9	S363 A364 F367 A387 S388 G389 A393 A394 A395	S363-A391 WeakPolarHBondContact OG-CB 3.29Å; A364-A391 HydrophobicContact CB-CB 3.78Å; F367-A391 HydrophobicContact CD2-CB 4.12Å; F367-A391 HydrophobicContact CE2-CB 4.19Å; A387-A391 PolarHBondContact O-N 2.87Å; S388-A391 PolarHBondContact O-N 3.17Å; S388-A391 VanDerWaalsContact O-N 3.12Å; G389-A391 VanDerWaalsContact C-N 3.3Å; G389-A391 PolarHBondContact O-N 3.44Å; A391-A393 VanDerWaalsContact C-N 3.3Å; A391-A393 PolarHBondContact O-N 3.42Å; A391-A394 WeakPolarHBondContact O-CB 3.28Å; A391-A394 PolarHBondContact O-N 2.93Å; A391-A395 PolarHBondContact O-N 3.38Å
392	V	89.8	Confident	87.9	Confident	13 Å²	13	32.5 Å²	32.5	8%	0.079	16%	0.16	C	C	.	.	H	α-helix	trans	-59.5	-41.1	176.8	171.3	0	0	0	0	111.1	F305 I333 A337 S388 G389 A394 A395 F396	F305-V392 HydrophobicContact CD1-CG2 4.08Å; F305-V392 HydrophobicContact CE1-CG2 4Å; I333-V392 HydrophobicContact CG2-CG2 4.5Å; A337-V392 HydrophobicContact CB-CB 4.48Å; A337-V392 HydrophobicContact CB-CG1 4.41Å; S388-V392 WeakPolarHBondContact O-CG2 2.92Å; S388-V392 PolarHBondContact O-N 3.4Å; G389-V392 PolarHBondContact O-N 3.32Å; V392-A394 VanDerWaalsContact C-N 3.3Å; V392-A394 PolarHBondContact O-N 3.26Å; V392-A395 WeakPolarHBondContact O-CB 3.34Å; V392-A395 PolarHBondContact O-N 3.03Å; V392-A395 VanDerWaalsContact O-N 3.14Å; V392-F396 HydrophobicContact CG1-CD2 3.65Å; V392-F396 HydrophobicContact CG1-CE2 3.64Å; V392-F396 WeakPolarHBondContact O-CD2 3.26Å; V392-F396 PolarHBondContact O-N 3.15Å; V392-F396 VanDerWaalsContact O-N 3.09Å
393	A	90.3	Very high	87.7	Confident	4 Å²	4	29.2 Å²	29.2	3%	0.033	15%	0.147	C	C	.	.	H	α-helix	trans	-58.1	-40.3	178	0	0	0	0	0	113.1	A337 A340 I341 G389 V390 A391 L397	A337-A393 HydrophobicContact CB-CB 4.29Å; A337-A393 WeakPolarHBondContact O-CB 3.05Å; A340-A393 HydrophobicContact CB-CB 3.83Å; I341-A393 HydrophobicContact CG1-CB 4.37Å; G389-A393 PolarHBondContact O-N 2.63Å; V390-A393 PolarHBondContact O-N 3.32Å; A391-A393 VanDerWaalsContact C-N 3.3Å; A391-A393 PolarHBondContact O-N 3.42Å; A393-L397 WeakPolarHBondContact O-CB 3.46Å; A393-L397 PolarHBondContact O-N 3.46Å; A393-L397 VanDerWaalsContact O-N 3.15Å
394	A	89.4	Confident	87.4	Confident	0 Å²	0	26 Å²	26	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-61.9	-49.2	175.4	0	0	0	0	0	110.7	W344 A391 V392 F396 L397 L398	W344-A394 HydrophobicContact CD2-CB 3.72Å; W344-A394 HydrophobicContact CE3-CB 4.1Å; W344-A394 HydrophobicContact CG-CB 4.18Å; W344-A394 HydrophobicContact CH2-CB 4.2Å; W344-A394 HydrophobicContact CZ2-CB 3.81Å; W344-A394 HydrophobicContact CZ3-CB 4.33Å; A391-A394 WeakPolarHBondContact O-CB 3.28Å; A391-A394 PolarHBondContact O-N 2.93Å; V392-A394 VanDerWaalsContact C-N 3.3Å; V392-A394 PolarHBondContact O-N 3.26Å; A394-F396 PolarHBondContact O-N 3.26Å; A394-L397 PolarHBondContact O-N 3.29Å; A394-L397 VanDerWaalsContact O-N 3.09Å; A394-L398 HydrophobicContact CB-CD1 3.95Å; A394-L398 WeakPolarHBondContact O-CB 3.48Å; A394-L398 WeakPolarHBondContact O-CD1 3.23Å; A394-L398 WeakPolarHBondContact O-CG 3.48Å; A394-L398 PolarHBondContact O-N 2.86Å
395	A	86.8	Confident	87.3	Confident	18 Å²	18	26.4 Å²	26.4	15%	0.149	14%	0.135	C	C	.	.	H	α-helix	trans	-59.5	-34.9	-177.2	0	0	0	0	0	113.1	F305 A391 V392 P399	F305-A395 HydrophobicContact CD1-CB 4.32Å; F305-A395 HydrophobicContact CD2-CB 3.48Å; F305-A395 VanDerWaalsContact CD2-CB 3.48Å; F305-A395 HydrophobicContact CE1-CB 4.05Å; F305-A395 HydrophobicContact CE2-CB 3.2Å; F305-A395 HydrophobicContact CG-CB 4.06Å; F305-A395 HydrophobicContact CZ-CB 3.5Å; F305-A395 VanDerWaalsContact CZ-CB 3.5Å; A391-A395 PolarHBondContact O-N 3.38Å; V392-A395 WeakPolarHBondContact O-CB 3.34Å; V392-A395 PolarHBondContact O-N 3.03Å; V392-A395 VanDerWaalsContact O-N 3.14Å; A395-P399 WeakPolarHBondContact O-CD 3.45Å; A395-P399 WeakPolarHBondContact O-CG 3.45Å
396	F	83.1	Confident	87.2	Confident	112 Å²	112	26.4 Å²	26.4	49%	0.491	14%	0.135	S	C	.	.	H	α-helix	trans	-72.7	-40.6	174	-87.5	-80.9	0	0	0	112.9	V392 A394	V392-F396 HydrophobicContact CG1-CD2 3.65Å; V392-F396 HydrophobicContact CG1-CE2 3.64Å; V392-F396 WeakPolarHBondContact O-CD2 3.26Å; V392-F396 PolarHBondContact O-N 3.15Å; V392-F396 VanDerWaalsContact O-N 3.09Å; A394-F396 PolarHBondContact O-N 3.26Å
397	L	84.5	Confident	86.9	Confident	30 Å²	30	21.2 Å²	21.2	16%	0.157	11%	0.113	C	C	.	.	H	α-helix	trans	-78.4	-42.9	-171.9	-162.3	171.7	0	0	0	112.5	I341 W344 Q345 L348 A393 A394 W400 S401	I341-L397 HydrophobicContact CG2-CD1 4.19Å; W344-L397 HydrophobicContact CB-CD1 4.13Å; Q345-L397 HydrophobicContact CB-CD1 4.41Å; L348-L397 HydrophobicContact CD1-CD1 4.06Å; L348-L397 HydrophobicContact CD1-CD2 3.22Å; L348-L397 HydrophobicContact CD1-CG 4.21Å; A393-L397 WeakPolarHBondContact O-CB 3.46Å; A393-L397 PolarHBondContact O-N 3.46Å; A393-L397 VanDerWaalsContact O-N 3.15Å; A394-L397 PolarHBondContact O-N 3.29Å; A394-L397 VanDerWaalsContact O-N 3.09Å; L397-W400 PolarHBondContact O-N 3.41Å; L397-S401 PolarHBondContact O-N 2.94Å
398	L	85.3	Confident	86.6	Confident	2 Å²	2	22.5 Å²	22.5	1%	0.01	12%	0.117	C	C	.	.	H	α-helix	trans	-57.6	-45.5	-169.2	-71.4	160.2	0	0	0	115.3	F298 L348 A356 A357 A394 W400 S401 M402	F298-L398 HydrophobicContact CE1-CB 4.04Å; F298-L398 HydrophobicContact CZ-CB 4.19Å; L348-L398 HydrophobicContact CD2-CD2 3.66Å; A356-L398 HydrophobicContact CB-CD2 3.82Å; A357-L398 HydrophobicContact CB-CD1 4.23Å; A357-L398 HydrophobicContact CB-CD2 4.08Å; A394-L398 HydrophobicContact CB-CD1 3.95Å; A394-L398 WeakPolarHBondContact O-CB 3.48Å; A394-L398 WeakPolarHBondContact O-CD1 3.23Å; A394-L398 WeakPolarHBondContact O-CG 3.48Å; A394-L398 PolarHBondContact O-N 2.86Å; L398-W400 VanDerWaalsContact C-N 3.33Å; L398-W400 PolarHBondContact O-N 3.41Å; L398-S401 PolarHBondContact O-N 3.3Å; L398-S401 VanDerWaalsContact O-N 3.15Å; L398-M402 PolarHBondContact O-N 3.34Å
399	P	84.5	Confident	86.4	Confident	3 Å²	3	22.1 Å²	22.1	2%	0.019	11%	0.114	C	C	.	.	H	α-helix	trans	-63.5	-40.4	-177.3	-17	28.4	0	0	0	112.5	F298 A395 S401 M402 L403 Y428	F298-P399 HydrophobicContact CD1-CB 4.03Å; F298-P399 HydrophobicContact CD1-CG 3.63Å; F298-P399 HydrophobicContact CD2-CB 4.03Å; F298-P399 HydrophobicContact CE1-CB 4.14Å; F298-P399 HydrophobicContact CE1-CG 3.74Å; F298-P399 HydrophobicContact CE2-CB 4.13Å; F298-P399 HydrophobicContact CG-CB 3.98Å; F298-P399 HydrophobicContact CG-CG 4.05Å; F298-P399 HydrophobicContact CZ-CB 4.19Å; F298-P399 HydrophobicContact CZ-CG 4.25Å; A395-P399 WeakPolarHBondContact O-CD 3.45Å; A395-P399 WeakPolarHBondContact O-CG 3.45Å; P399-S401 VanDerWaalsContact C-N 3.25Å; P399-S401 PolarHBondContact O-N 3.5Å; P399-M402 PolarHBondContact O-N 3.05Å; P399-L403 VanDerWaalsContact O-CB 3.25Å; P399-L403 WeakPolarHBondContact O-CB 3.35Å; P399-L403 PolarHBondContact O-N 3.04Å; P399-Y428 HydrophobicContact CB-CE1 4.24Å; P399-Y428 HydrophobicContact CB-CE2 4.14Å; P399-Y428 WeakPolarHBondContact CB-OH 3.34Å; P399-Y428 WeakPolarHBondContact CG-OH 3.48Å
400	W	82.2	Confident	86.2	Confident	109 Å²	109	22.5 Å²	22.5	41%	0.413	12%	0.116	S	C	.	.	H	α-helix	trans	-68.5	-25.7	178	-63.5	108.5	0	0	0	112.9	L397 L398 P404 Y425 Y428 V429	L397-W400 PolarHBondContact O-N 3.41Å; L398-W400 VanDerWaalsContact C-N 3.33Å; L398-W400 PolarHBondContact O-N 3.41Å; W400-P404 WeakPolarHBondContact O-CD 3.45Å; W400-Y425 HydrophobicContact CE3-CD1 4.28Å; W400-Y425 HydrophobicContact CE3-CE1 4.24Å; W400-Y425 AromaticContact CZ3-CD1 3.87Å; W400-Y425 HydrophobicContact CZ3-CD1 3.87Å; W400-Y425 HydrophobicContact CZ3-CE1 4.27Å; W400-Y428 HydrophobicContact CZ2-CE1 4.5Å; W400-V429 HydrophobicContact CH2-CG2 3.79Å; W400-V429 HydrophobicContact CZ2-CG2 4.47Å
401	S	84.5	Confident	85.8	Confident	23 Å²	23	23.2 Å²	23.2	16%	0.161	12%	0.116	C	C	.	.	H	α-helix	trans	-79.1	-36.5	175.6	-168.9	0	0	0	0	112.7	K353 L397 L398 P399	K353-S401 WeakPolarHBondContact CE-OG 3.31Å; K353-S401 PolarHBondContact NZ-O 3.01Å; L397-S401 PolarHBondContact O-N 2.94Å; L398-S401 PolarHBondContact O-N 3.3Å; L398-S401 VanDerWaalsContact O-N 3.15Å; P399-S401 VanDerWaalsContact C-N 3.25Å; P399-S401 PolarHBondContact O-N 3.5Å
402	M	87.4	Confident	85.5	Confident	6 Å²	6	24.9 Å²	24.9	3%	0.03	13%	0.126	C	C	.	.	H	α-helix	trans	-89	-24	-175.1	-67.6	-176.3	69.7	0	0	114	L294 F298 K353 A357 L398 P399 D405 Y489	L294-M402 HydrophobicContact CD1-CB 4.14Å; L294-M402 HydrophobicContact CD1-CE 3.85Å; L294-M402 HydrophobicContact CD2-CB 4.32Å; F298-M402 HydrophobicContact CE2-CB 4.05Å; F298-M402 HydrophobicContact CE2-SD 4.05Å; F298-M402 HydrophobicContact CZ-CB 4.33Å; F298-M402 HydrophobicContact CZ-CG 4.35Å; F298-M402 HydrophobicContact CZ-SD 3.63Å; K353-M402 HydrophobicContact CB-CG 4.04Å; K353-M402 HydrophobicContact CD-CG 4.27Å; A357-M402 HydrophobicContact CB-SD 4.12Å; L398-M402 PolarHBondContact O-N 3.34Å; P399-M402 PolarHBondContact O-N 3.05Å; M402-D405 WeakPolarHBondContact O-CB 3.39Å; M402-D405 PolarHBondContact O-N 2.91Å; M402-Y489 HydrophobicContact CE-CD1 4.06Å; M402-Y489 HydrophobicContact CE-CE1 3.73Å
403	L	84.4	Confident	85.2	Confident	1 Å²	1	28.7 Å²	28.7	1%	0.005	14%	0.143	C	C	.	.	H	α-helix	trans	-61.6	-44.4	179.5	-176.8	61.9	0	0	0	113.9	Y291 L294 P399 D405 V406 V407 Y425 Y428	Y291-L403 HydrophobicContact CD2-CD1 4.25Å; Y291-L403 HydrophobicContact CE2-CD1 3.78Å; L294-L403 HydrophobicContact CD2-CD1 4.47Å; P399-L403 VanDerWaalsContact O-CB 3.25Å; P399-L403 WeakPolarHBondContact O-CB 3.35Å; P399-L403 PolarHBondContact O-N 3.04Å; L403-D405 PolarHBondContact O-N 3.14Å; L403-V406 PolarHBondContact O-N 2.74Å; L403-V407 PolarHBondContact O-N 3.2Å; L403-Y425 HydrophobicContact CD2-CD1 3.33Å; L403-Y425 HydrophobicContact CD2-CE1 3.52Å; L403-Y425 HydrophobicContact CD2-CG 4.06Å; L403-Y425 HydrophobicContact CG-CD1 4.22Å; L403-Y425 HydrophobicContact CG-CE1 4.02Å; L403-Y428 HydrophobicContact CD2-CD1 4.03Å; L403-Y428 HydrophobicContact CD2-CG 4.01Å
404	P	82.5	Confident	84.7	Confident	37 Å²	37	30.9 Å²	30.9	24%	0.24	16%	0.155	C	C	.	.	H	α-helix	trans	-56.2	-36.7	173.6	-18.5	24.2	0	0	0	113.2	W400 V406 V407 D408 Y425	W400-P404 WeakPolarHBondContact O-CD 3.45Å; P404-V406 PolarHBondContact O-N 3.45Å; P404-V407 WeakPolarHBondContact O-CA 3.44Å; P404-V407 WeakPolarHBondContact O-CB 3.23Å; P404-V407 PolarHBondContact O-N 3.32Å; P404-D408 PolarHBondContact O-N 3.09Å; P404-Y425 WeakPolarHBondContact CG-OH 3.29Å
405	D	85.1	Confident	83.9	Confident	12 Å²	12	34.9 Å²	34.9	6%	0.064	18%	0.18	C	C	.	.	H	α-helix	trans	-63.7	-30.8	-177	-57.5	-21.5	0	0	0	112.4	K353 M402 L403 D409 R496	K353-D405 WeakPolarHBondContact CD-OD2 3.4Å; K353-D405 WeakPolarHBondContact CE-OD2 3.45Å; K353-D405 IonicContact NZ-OD1 3.93Å; K353-D405 PolarHBondContact NZ-OD1 3.42Å; K353-D405 IonicContact NZ-OD2 3.64Å; K353-D405 PolarHBondContact NZ-OD2 2.96Å; M402-D405 WeakPolarHBondContact O-CB 3.39Å; M402-D405 PolarHBondContact O-N 2.91Å; L403-D405 PolarHBondContact O-N 3.14Å; D405-D409 WeakPolarHBondContact O-CB 3.47Å; D405-D409 PolarHBondContact O-N 3.38Å; D405-D409 VanDerWaalsContact O-N 3.15Å; D405-R496 WeakPolarHBondContact OD1-CD 3.47Å; D405-R496 WeakPolarHBondContact OD2-CD 3.5Å
406	V	87.7	Confident	82.9	Confident	0 Å²	0	43.3 Å²	43.3	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-74.9	-37.8	175	179.5	0	0	0	0	111.1	Y288 Y291 L294 L403 P404 D409 F410 Y489 I491	Y288-V406 HydrophobicContact CD1-CG1 3.96Å; Y288-V406 HydrophobicContact CE1-CG1 3.87Å; Y291-V406 HydrophobicContact CD2-CG1 4.08Å; Y291-V406 HydrophobicContact CG-CG1 4.38Å; L294-V406 HydrophobicContact CB-CG2 4.34Å; L294-V406 HydrophobicContact CD2-CG2 3.49Å; L294-V406 VanDerWaalsContact CD2-CG2 3.49Å; L294-V406 HydrophobicContact CG-CG2 4.41Å; L403-V406 PolarHBondContact O-N 2.74Å; P404-V406 PolarHBondContact O-N 3.45Å; V406-D409 PolarHBondContact O-N 2.84Å; V406-F410 WeakPolarHBondContact O-CB 3.23Å; V406-F410 PolarHBondContact O-N 2.95Å; V406-Y489 HydrophobicContact CG2-CE2 3.96Å; V406-Y489 WeakPolarHBondContact CG2-OH 3.25Å; V406-I491 HydrophobicContact CB-CD1 4.5Å; V406-I491 HydrophobicContact CG2-CD1 3.97Å
407	V	83.7	Confident	82	Confident	7 Å²	7	39.3 Å²	39.3	4%	0.042	20%	0.202	C	C	.	.	H	α-helix	trans	-64.2	-45.3	177.2	176.7	0	0	0	0	109.7	L403 P404 D409 F410 Q411 E421 F424	L403-V407 PolarHBondContact O-N 3.2Å; P404-V407 WeakPolarHBondContact O-CA 3.44Å; P404-V407 WeakPolarHBondContact O-CB 3.23Å; P404-V407 PolarHBondContact O-N 3.32Å; V407-D409 PolarHBondContact O-N 3.24Å; V407-F410 WeakPolarHBondContact O-CB 3.46Å; V407-F410 PolarHBondContact O-N 3.46Å; V407-Q411 WeakPolarHBondContact O-CB 3.19Å; V407-Q411 PolarHBondContact O-N 3.4Å; V407-E421 HydrophobicContact CG1-CB 3.91Å; V407-E421 HydrophobicContact CG1-CG 3.59Å; V407-F424 HydrophobicContact CG2-CB 3.83Å; V407-F424 HydrophobicContact CG2-CD1 4.45Å; V407-F424 HydrophobicContact CG2-CD2 4.21Å; V407-F424 HydrophobicContact CG2-CG 3.93Å
408	D	84.2	Confident	80.7	Confident	47 Å²	47	40.5 Å²	40.5	25%	0.251	22%	0.217	S	C	.	.	H	α-helix	trans	-58.9	-47.4	174.6	-70.9	-5.7	0	0	0	111.4	P404 F410 Q411 V412 L503	P404-D408 PolarHBondContact O-N 3.09Å; D408-F410 VanDerWaalsContact C-N 3.27Å; D408-F410 PolarHBondContact O-N 3.39Å; D408-Q411 PolarHBondContact O-N 2.86Å; D408-V412 WeakPolarHBondContact O-CG2 3.38Å; D408-V412 PolarHBondContact O-N 3.34Å; D408-L503 HydrophobicContact CB-CD1 3.6Å
409	D	86.4	Confident	79.5	Confident	2 Å²	2	42.5 Å²	42.5	1%	0.011	24%	0.238	C	C	.	.	H	α-helix	trans	-63.5	-33.2	178.2	-170.9	63.1	0	0	0	112.7	Y288 D405 V406 V407 Q413 I491 R495 N499	Y288-D409 PolarHBondContact OH-OD2 3.3Å; D405-D409 WeakPolarHBondContact O-CB 3.47Å; D405-D409 PolarHBondContact O-N 3.38Å; D405-D409 VanDerWaalsContact O-N 3.15Å; V406-D409 PolarHBondContact O-N 2.84Å; V407-D409 PolarHBondContact O-N 3.24Å; D409-Q413 WeakPolarHBondContact O-CG 3.41Å; D409-Q413 PolarHBondContact O-N 2.8Å; D409-Q413 PolarHBondContact O-NE2 3.26Å; D409-Q413 PolarHBondContact OD2-NE2 2.98Å; D409-I491 HydrophobicContact CB-CD1 3.89Å; D409-R495 IonicContact OD1-CZ 3.35Å; D409-R495 IonicContact OD1-NE 3.84Å; D409-R495 PolarHBondContact OD1-NE 3.48Å; D409-R495 IonicContact OD1-NH2 2.95Å; D409-R495 PolarHBondContact OD1-NH2 3.17Å; D409-R495 IonicContact OD2-CZ 3.81Å; D409-R495 IonicContact OD2-NE 3.77Å; D409-R495 IonicContact OD2-NH2 3.19Å; D409-R495 PolarHBondContact OD2-NH2 2.87Å; D409-N499 VanDerWaalsContact CA-ND2 3.29Å; D409-N499 WeakPolarHBondContact CA-ND2 3.49Å; D409-N499 VanDerWaalsContact CB-ND2 3.25Å; D409-N499 WeakPolarHBondContact CB-ND2 3.45Å; D409-N499 PolarHBondContact OD1-ND2 3.21Å
410	F	86	Confident	78.8	Confident	9 Å²	9	43.6 Å²	43.6	4%	0.039	24%	0.242	C	C	.	.	H	α-helix	trans	-71.7	-40.7	174.2	178	-95.8	0	0	0	112.3	M284 Y288 V406 V407 D408 Q413 N414 F424	M284-F410 HydrophobicContact CE-CE1 4.32Å; M284-F410 HydrophobicContact CE-CE2 4.22Å; M284-F410 HydrophobicContact CE-CZ 3.45Å; M284-F410 VanDerWaalsContact CE-CZ 3.45Å; M284-F410 HydrophobicContact CG-CE2 4.34Å; M284-F410 HydrophobicContact CG-CZ 4Å; M284-F410 HydrophobicContact SD-CZ 3.99Å; Y288-F410 HydrophobicContact CD1-CB 4.43Å; Y288-F410 HydrophobicContact CD1-CD2 4.21Å; Y288-F410 AromaticContact CD2-CD2 3.91Å; Y288-F410 HydrophobicContact CD2-CD2 3.91Å; Y288-F410 HydrophobicContact CE1-CB 4.13Å; Y288-F410 HydrophobicContact CE1-CD2 4.49Å; Y288-F410 HydrophobicContact CE2-CD2 4.21Å; Y288-F410 AromaticContact CG-CD2 3.93Å; Y288-F410 HydrophobicContact CG-CD2 3.93Å; V406-F410 WeakPolarHBondContact O-CB 3.23Å; V406-F410 PolarHBondContact O-N 2.95Å; V407-F410 WeakPolarHBondContact O-CB 3.46Å; V407-F410 PolarHBondContact O-N 3.46Å; D408-F410 VanDerWaalsContact C-N 3.27Å; D408-F410 PolarHBondContact O-N 3.39Å; F410-Q413 PolarHBondContact O-N 3.45Å; F410-N414 HydrophobicContact CE1-CB 4.41Å; F410-N414 HydrophobicContact CZ-CB 4.48Å; F410-N414 WeakPolarHBondContact O-CB 3.27Å; F410-N414 PolarHBondContact O-N 3.3Å; F410-N414 PolarHBondContact O-ND2 3.47Å; F410-F424 HydrophobicContact CB-CZ 4.13Å; F410-F424 AromaticContact CD1-CE2 3.78Å; F410-F424 HydrophobicContact CD1-CE2 3.78Å; F410-F424 AromaticContact CD1-CZ 3.7Å; F410-F424 HydrophobicContact CD1-CZ 3.7Å; F410-F424 AromaticContact CD2-CZ 3.86Å; F410-F424 HydrophobicContact CD2-CZ 3.86Å; F410-F424 AromaticContact CE1-CE2 3.94Å; F410-F424 HydrophobicContact CE1-CE2 3.94Å; F410-F424 AromaticContact CE1-CZ 3.98Å; F410-F424 HydrophobicContact CE1-CZ 3.98Å; F410-F424 HydrophobicContact CE2-CZ 4.11Å; F410-F424 HydrophobicContact CG-CE2 4.17Å; F410-F424 AromaticContact CG-CZ 3.62Å; F410-F424 HydrophobicContact CG-CZ 3.62Å; F410-F424 HydrophobicContact CZ-CE2 4.45Å; F410-F424 HydrophobicContact CZ-CZ 4.14Å
411	Q	82	Confident	78.3	Confident	52 Å²	52	42.6 Å²	42.6	24%	0.243	24%	0.242	C	C	.	.	H	α-helix	trans	-67.2	-40	179.4	-173.6	173.3	3.9	0	0	111.8	V407 D408 Q413 N414 L503	V407-Q411 WeakPolarHBondContact O-CB 3.19Å; V407-Q411 PolarHBondContact O-N 3.4Å; D408-Q411 PolarHBondContact O-N 2.86Å; Q411-Q413 VanDerWaalsContact C-N 3.25Å; Q411-Q413 PolarHBondContact O-N 3.24Å; Q411-N414 CarbonylContact O-C 3.17Å; Q411-N414 PolarHBondContact O-N 3.32Å; Q411-L503 HydrophobicContact CB-CD2 4.27Å; Q411-L503 HydrophobicContact CG-CD2 3.87Å
412	V	85.1	Confident	77.6	Confident	35 Å²	35	44.6 Å²	44.6	21%	0.212	26%	0.261	C	S	.	.	H	α-helix	trans	-60.2	-37.3	173.9	170.5	0	0	0	0	111.5	D408 N499 I502 L503	D408-V412 WeakPolarHBondContact O-CG2 3.38Å; D408-V412 PolarHBondContact O-N 3.34Å; V412-N499 HydrophobicContact CG2-CB 4.04Å; V412-I502 HydrophobicContact CG1-CD1 4.02Å; V412-I502 HydrophobicContact CG1-CG2 4.09Å; V412-I502 HydrophobicContact CG2-CB 4.35Å; V412-I502 HydrophobicContact CG2-CG2 4.23Å; V412-L503 HydrophobicContact CG2-CD1 4.01Å; V412-L503 HydrophobicContact CG2-CD2 4.31Å; V412-L503 HydrophobicContact CG2-CG 3.77Å
413	Q	83.4	Confident	77.1	Confident	93 Å²	93	46.6 Å²	46.6	44%	0.435	27%	0.271	S	S	.	.	H	α-helix	trans	-79.9	-24.4	177.5	-71.4	171.9	40.8	0	0	113.3	Y288 D409 F410 Q411 R495	Y288-Q413 PolarHBondContact OH-NE2 2.99Å; Y288-Q413 PolarHBondContact OH-OE1 3.39Å; D409-Q413 WeakPolarHBondContact O-CG 3.41Å; D409-Q413 PolarHBondContact O-N 2.8Å; D409-Q413 PolarHBondContact O-NE2 3.26Å; D409-Q413 PolarHBondContact OD2-NE2 2.98Å; F410-Q413 PolarHBondContact O-N 3.45Å; Q411-Q413 VanDerWaalsContact C-N 3.25Å; Q411-Q413 PolarHBondContact O-N 3.24Å; Q413-R495 VanDerWaalsContact NE2-NH2 3.14Å
414	N	81.5	Confident	76.9	Confident	51 Å²	51	46.6 Å²	46.6	27%	0.273	27%	0.271	S	S	.	.			trans	-132.5	68.6	-175.5	-56.5	-88.4	0	0	0	111	F410 Q411 E416 S417	F410-N414 HydrophobicContact CE1-CB 4.41Å; F410-N414 HydrophobicContact CZ-CB 4.48Å; F410-N414 WeakPolarHBondContact O-CB 3.27Å; F410-N414 PolarHBondContact O-N 3.3Å; F410-N414 PolarHBondContact O-ND2 3.47Å; Q411-N414 CarbonylContact O-C 3.17Å; Q411-N414 PolarHBondContact O-N 3.32Å; N414-E416 VanDerWaalsContact C-N 3.26Å; N414-E416 PolarHBondContact O-N 2.84Å; N414-S417 PolarHBondContact O-N 3.17Å
415	P	71.9	Confident	76.8	Confident	83 Å²	83	48.2 Å²	48.2	54%	0.539	27%	0.273	S	S	.	.	G	3₁₀ helix	trans	-62.9	-29.9	-176.2	21.8	-31.7	0	0	0	113.2	S417	P415-S417 PolarHBondContact O-N 2.93Å
416	E	65.7	Low	76.5	Confident	196 Å²	196	50.5 Å²	50.5	92%	0.916	29%	0.29	S	S	*	.	G	3₁₀ helix	trans	-70.7	-11.9	175.6	-64	-169.1	167.5	0	0	113.8	N414	N414-E416 VanDerWaalsContact C-N 3.26Å; N414-E416 PolarHBondContact O-N 2.84Å
417	S	63.8	Low	76.2	Confident	27 Å²	27	51.4 Å²	51.4	19%	0.189	29%	0.294	C	S	.	.	G	3₁₀ helix	trans	-103.9	44	-177.6	-66.2	0	0	0	0	112	N414 P415 H420	N414-S417 PolarHBondContact O-N 3.17Å; P415-S417 PolarHBondContact O-N 2.93Å; S417-H420 VanDerWaalsContact C-ND1 3.34Å; S417-H420 PolarHBondContact O-CE1 3.29Å; S417-H420 PolarHBondContact O-ND1 2.81Å
418	A	56.4	Low	76.3	Confident	55 Å²	55	51.7 Å²	51.7	46%	0.455	29%	0.294	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.6	138.4	173.3	0	0	0	0	0	111.7
419	G	62	Low	76.3	Confident	44 Å²	44	50.9 Å²	50.9	45%	0.454	29%	0.291	S	S	.	.	T	Hydrogen-bonded Turn	trans	97.4	13.3	175	0	0	0	0	0	116.9
420	H	68.6	Low	76.3	Confident	26 Å²	26	53.4 Å²	53.4	12%	0.12	30%	0.302	C	S	.	.			trans	-92.9	1.1	177.4	-58.7	100.9	0	0	0	114.7	M276 S417 A422 I423 F424	M276-H420 WeakPolarHBondContact CE-NE2 3.41Å; S417-H420 VanDerWaalsContact C-ND1 3.34Å; S417-H420 PolarHBondContact O-CE1 3.29Å; S417-H420 PolarHBondContact O-ND1 2.81Å; H420-A422 VanDerWaalsContact C-N 3.28Å; H420-A422 PolarHBondContact O-N 3.45Å; H420-I423 HydrophobicContact CB-CD1 4.5Å; H420-I423 WeakPolarHBondContact O-CB 3.45Å; H420-I423 PolarHBondContact O-N 3.01Å; H420-F424 HydrophobicContact CB-CE2 4.42Å; H420-F424 WeakPolarHBondContact O-CD2 3.43Å
421	E	71.8	Confident	76.3	Confident	88 Å²	88	55.4 Å²	55.4	41%	0.411	31%	0.31	S	S	.	.	H	α-helix	trans	-52.8	-45.8	-176.1	-46.7	-178.2	178.6	0	0	111.8	V407 I423 F424 Y425	V407-E421 HydrophobicContact CG1-CB 3.91Å; V407-E421 HydrophobicContact CG1-CG 3.59Å; E421-I423 PolarHBondContact O-N 3.42Å; E421-I423 VanDerWaalsContact O-N 3.13Å; E421-F424 WeakPolarHBondContact O-CB 3.46Å; E421-F424 PolarHBondContact O-N 3.48Å; E421-Y425 WeakPolarHBondContact O-CD2 3.21Å; E421-Y425 PolarHBondContact O-N 3.09Å
422	A	69.4	Low	76.6	Confident	66 Å²	66	54.2 Å²	54.2	55%	0.545	31%	0.307	S	S	.	.	H	α-helix	trans	-55.9	-34.2	179.8	0	0	0	0	0	113	H420 Y425 S426	H420-A422 VanDerWaalsContact C-N 3.28Å; H420-A422 PolarHBondContact O-N 3.45Å; A422-Y425 PolarHBondContact O-N 2.6Å; A422-S426 WeakPolarHBondContact O-CB 3.45Å; A422-S426 PolarHBondContact O-N 3.39Å; A422-S426 PolarHBondContact O-OG 3.36Å; A422-S426 VanDerWaalsContact O-OG 3.05Å
423	I	77.8	Confident	76.7	Confident	47 Å²	47	53.2 Å²	53.2	24%	0.241	30%	0.3	C	S	.	.	H	α-helix	trans	-67.6	-42.5	179.5	-56.4	179.6	0	0	0	110.2	V285 H420 E421 Y425 S426 F427	V285-I423 HydrophobicContact CG2-CB 4.42Å; V285-I423 HydrophobicContact CG2-CG2 3.84Å; H420-I423 HydrophobicContact CB-CD1 4.5Å; H420-I423 WeakPolarHBondContact O-CB 3.45Å; H420-I423 PolarHBondContact O-N 3.01Å; E421-I423 PolarHBondContact O-N 3.42Å; E421-I423 VanDerWaalsContact O-N 3.13Å; I423-Y425 VanDerWaalsContact C-N 3.33Å; I423-Y425 PolarHBondContact O-N 3.31Å; I423-S426 PolarHBondContact O-N 2.77Å; I423-F427 HydrophobicContact CG2-CD2 3.63Å; I423-F427 HydrophobicContact CG2-CE2 3.58Å; I423-F427 VanDerWaalsContact O-CD2 3.28Å; I423-F427 WeakPolarHBondContact O-CD2 3.37Å; I423-F427 PolarHBondContact O-N 3.25Å
424	F	80.9	Confident	76.9	Confident	1 Å²	1	52.7 Å²	52.7	0%	0.004	30%	0.296	C	S	.	.	H	α-helix	trans	-60.6	-42.2	176.9	-72.9	-91.9	0	0	0	111.9	V285 Y291 V407 F410 H420 E421 Y428	V285-F424 HydrophobicContact CB-CE1 4.29Å; V285-F424 HydrophobicContact CB-CZ 4.46Å; V285-F424 HydrophobicContact CG1-CD1 3.72Å; V285-F424 HydrophobicContact CG1-CE1 3.8Å; V285-F424 HydrophobicContact CG1-CG 4.26Å; V285-F424 HydrophobicContact CG1-CZ 4.41Å; V285-F424 HydrophobicContact CG2-CD1 4.29Å; V285-F424 HydrophobicContact CG2-CD2 4.12Å; V285-F424 HydrophobicContact CG2-CE1 4.03Å; V285-F424 HydrophobicContact CG2-CE2 3.84Å; V285-F424 HydrophobicContact CG2-CG 4.33Å; V285-F424 HydrophobicContact CG2-CZ 3.79Å; Y291-F424 HydrophobicContact CD1-CD1 4.38Å; Y291-F424 AromaticContact CD2-CD1 3.45Å; Y291-F424 HydrophobicContact CD2-CD1 3.45Å; Y291-F424 VanDerWaalsContact CD2-CD1 3.45Å; Y291-F424 HydrophobicContact CD2-CE1 4.01Å; Y291-F424 HydrophobicContact CE1-CD1 4.49Å; Y291-F424 HydrophobicContact CE2-CB 4.11Å; Y291-F424 AromaticContact CE2-CD1 3.54Å; Y291-F424 HydrophobicContact CE2-CD1 3.54Å; Y291-F424 HydrophobicContact CE2-CE1 4.46Å; Y291-F424 HydrophobicContact CE2-CG 4.31Å; Y291-F424 AromaticContact CG-CD1 3.85Å; Y291-F424 HydrophobicContact CG-CD1 3.85Å; Y291-F424 AromaticContact CG-CE1 3.98Å; Y291-F424 HydrophobicContact CG-CE1 3.98Å; Y291-F424 PolarHBondContact OH-O 3.08Å; V407-F424 HydrophobicContact CG2-CB 3.83Å; V407-F424 HydrophobicContact CG2-CD1 4.45Å; V407-F424 HydrophobicContact CG2-CD2 4.21Å; V407-F424 HydrophobicContact CG2-CG 3.93Å; F410-F424 HydrophobicContact CB-CZ 4.13Å; F410-F424 AromaticContact CD1-CE2 3.78Å; F410-F424 HydrophobicContact CD1-CE2 3.78Å; F410-F424 AromaticContact CD1-CZ 3.7Å; F410-F424 HydrophobicContact CD1-CZ 3.7Å; F410-F424 AromaticContact CD2-CZ 3.86Å; F410-F424 HydrophobicContact CD2-CZ 3.86Å; F410-F424 AromaticContact CE1-CE2 3.94Å; F410-F424 HydrophobicContact CE1-CE2 3.94Å; F410-F424 AromaticContact CE1-CZ 3.98Å; F410-F424 HydrophobicContact CE1-CZ 3.98Å; F410-F424 HydrophobicContact CE2-CZ 4.11Å; F410-F424 HydrophobicContact CG-CE2 4.17Å; F410-F424 AromaticContact CG-CZ 3.62Å; F410-F424 HydrophobicContact CG-CZ 3.62Å; F410-F424 HydrophobicContact CZ-CE2 4.45Å; F410-F424 HydrophobicContact CZ-CZ 4.14Å; H420-F424 HydrophobicContact CB-CE2 4.42Å; H420-F424 WeakPolarHBondContact O-CD2 3.43Å; E421-F424 WeakPolarHBondContact O-CB 3.46Å; E421-F424 PolarHBondContact O-N 3.48Å; F424-Y428 WeakPolarHBondContact O-CB 3.22Å; F424-Y428 PolarHBondContact O-N 3.43Å
425	Y	80.4	Confident	77.3	Confident	71 Å²	71	50.5 Å²	50.5	28%	0.278	29%	0.285	S	S	.	.	H	α-helix	trans	-66.6	-47.6	176	-74.1	-79.4	0	0	0	112.6	W400 L403 P404 E421 A422 I423 F427 Y428 V429	W400-Y425 HydrophobicContact CE3-CD1 4.28Å; W400-Y425 HydrophobicContact CE3-CE1 4.24Å; W400-Y425 AromaticContact CZ3-CD1 3.87Å; W400-Y425 HydrophobicContact CZ3-CD1 3.87Å; W400-Y425 HydrophobicContact CZ3-CE1 4.27Å; L403-Y425 HydrophobicContact CD2-CD1 3.33Å; L403-Y425 HydrophobicContact CD2-CE1 3.52Å; L403-Y425 HydrophobicContact CD2-CG 4.06Å; L403-Y425 HydrophobicContact CG-CD1 4.22Å; L403-Y425 HydrophobicContact CG-CE1 4.02Å; P404-Y425 WeakPolarHBondContact CG-OH 3.29Å; E421-Y425 WeakPolarHBondContact O-CD2 3.21Å; E421-Y425 PolarHBondContact O-N 3.09Å; A422-Y425 PolarHBondContact O-N 2.6Å; I423-Y425 VanDerWaalsContact C-N 3.33Å; I423-Y425 PolarHBondContact O-N 3.31Å; Y425-F427 PolarHBondContact O-N 3.48Å; Y425-Y428 PolarHBondContact O-N 3.36Å; Y425-V429 WeakPolarHBondContact O-CG2 3.37Å; Y425-V429 PolarHBondContact O-N 3.11Å
426	S	78.4	Confident	78.2	Confident	61 Å²	61	46.7 Å²	46.7	43%	0.427	26%	0.26	S	S	.	.	H	α-helix	trans	-61	-41.5	-179.8	-63	0	0	0	0	112.5	A422 I423 V429 F430	A422-S426 WeakPolarHBondContact O-CB 3.45Å; A422-S426 PolarHBondContact O-N 3.39Å; A422-S426 PolarHBondContact O-OG 3.36Å; A422-S426 VanDerWaalsContact O-OG 3.05Å; I423-S426 PolarHBondContact O-N 2.77Å; S426-V429 PolarHBondContact O-N 3.14Å; S426-F430 WeakPolarHBondContact O-CB 3.21Å; S426-F430 PolarHBondContact O-N 3.08Å
427	F	81.1	Confident	79.3	Confident	18 Å²	18	37.4 Å²	37.4	8%	0.079	22%	0.217	C	C	.	.	H	α-helix	trans	-66.6	-41	177.3	-87.7	-66.1	0	0	0	112.9	F278 I282 Y291 I423 Y425 V429 F430 F431	F278-F427 HydrophobicContact CE2-CE2 4.45Å; F278-F427 HydrophobicContact CE2-CZ 4.08Å; F278-F427 AromaticContact CZ-CZ 3.84Å; F278-F427 HydrophobicContact CZ-CZ 3.84Å; I282-F427 HydrophobicContact CB-CE1 4.49Å; I282-F427 HydrophobicContact CB-CE2 4.19Å; I282-F427 HydrophobicContact CB-CZ 3.87Å; I282-F427 HydrophobicContact CD1-CE1 3.98Å; I282-F427 HydrophobicContact CD1-CE2 4.44Å; I282-F427 HydrophobicContact CD1-CZ 3.46Å; I282-F427 VanDerWaalsContact CD1-CZ 3.46Å; I282-F427 HydrophobicContact CG1-CE1 4.15Å; I282-F427 HydrophobicContact CG1-CE2 3.81Å; I282-F427 HydrophobicContact CG1-CZ 3.28Å; I282-F427 HydrophobicContact CG2-CE1 3.86Å; I282-F427 HydrophobicContact CG2-CE2 4.28Å; I282-F427 HydrophobicContact CG2-CZ 3.74Å; Y291-F427 WeakPolarHBondContact OH-CB 3.48Å; I423-F427 HydrophobicContact CG2-CD2 3.63Å; I423-F427 HydrophobicContact CG2-CE2 3.58Å; I423-F427 VanDerWaalsContact O-CD2 3.28Å; I423-F427 WeakPolarHBondContact O-CD2 3.37Å; I423-F427 PolarHBondContact O-N 3.25Å; Y425-F427 PolarHBondContact O-N 3.48Å; F427-V429 VanDerWaalsContact C-N 3.33Å; F427-V429 PolarHBondContact O-N 3.15Å; F427-F430 WeakPolarHBondContact O-CB 3.37Å; F427-F430 PolarHBondContact O-N 2.97Å; F427-F431 HydrophobicContact CD1-CE2 4.18Å; F427-F431 WeakPolarHBondContact O-CD2 3.42Å; F427-F431 PolarHBondContact O-N 3.07Å
428	Y	85.8	Confident	80.6	Confident	13 Å²	13	38 Å²	38	5%	0.051	22%	0.219	C	C	.	.	H	α-helix	trans	-59.8	-45.7	176.3	171.8	-98.6	0	0	0	111.4	Y291 V295 F298 P399 W400 L403 F424 Y425 F431 T432	Y291-Y428 PolarHBondContact OH-N 2.81Å; V295-Y428 HydrophobicContact CG2-CD2 4.35Å; F298-Y428 HydrophobicContact CB-CE2 4.02Å; P399-Y428 HydrophobicContact CB-CE1 4.24Å; P399-Y428 HydrophobicContact CB-CE2 4.14Å; P399-Y428 WeakPolarHBondContact CB-OH 3.34Å; P399-Y428 WeakPolarHBondContact CG-OH 3.48Å; W400-Y428 HydrophobicContact CZ2-CE1 4.5Å; L403-Y428 HydrophobicContact CD2-CD1 4.03Å; L403-Y428 HydrophobicContact CD2-CG 4.01Å; F424-Y428 WeakPolarHBondContact O-CB 3.22Å; F424-Y428 PolarHBondContact O-N 3.43Å; Y425-Y428 PolarHBondContact O-N 3.36Å; Y428-F431 PolarHBondContact O-N 2.63Å; Y428-T432 HydrophobicContact CD2-CG2 4.34Å; Y428-T432 HydrophobicContact CE1-CG2 4.12Å; Y428-T432 HydrophobicContact CE2-CG2 3.77Å; Y428-T432 WeakPolarHBondContact O-CG2 3.45Å; Y428-T432 PolarHBondContact O-N 3.24Å; Y428-T432 PolarHBondContact O-OG1 3.49Å
429	V	83.6	Confident	82.2	Confident	31 Å²	31	35.5 Å²	35.5	19%	0.188	20%	0.199	C	C	.	.	H	α-helix	trans	-65.1	-42.5	177.3	175.5	0	0	0	0	111.6	W400 Y425 S426 F427 F431 T432 K433	W400-V429 HydrophobicContact CH2-CG2 3.79Å; W400-V429 HydrophobicContact CZ2-CG2 4.47Å; Y425-V429 WeakPolarHBondContact O-CG2 3.37Å; Y425-V429 PolarHBondContact O-N 3.11Å; S426-V429 PolarHBondContact O-N 3.14Å; F427-V429 VanDerWaalsContact C-N 3.33Å; F427-V429 PolarHBondContact O-N 3.15Å; V429-F431 PolarHBondContact O-N 2.86Å; V429-T432 WeakPolarHBondContact CA-OG1 3.19Å; V429-T432 PolarHBondContact O-N 3.03Å; V429-T432 PolarHBondContact O-OG1 3.05Å; V429-K433 HydrophobicContact CG1-CD 4.09Å; V429-K433 HydrophobicContact CG1-CG 4.32Å; V429-K433 WeakPolarHBondContact O-CB 3.34Å; V429-K433 WeakPolarHBondContact O-CG 3.05Å; V429-K433 PolarHBondContact O-N 3.25Å
430	F	86	Confident	83.4	Confident	55 Å²	55	33.7 Å²	33.7	24%	0.241	18%	0.179	C	C	.	.	H	α-helix	trans	-54.3	-52.4	175.2	169.6	-93	0	0	0	111.5	A90 V91 S426 F427 T432 K433 F434	A90-F430 HydrophobicContact CB-CD2 4.01Å; A90-F430 HydrophobicContact CB-CE2 4.12Å; A90-F430 VanDerWaalsContact O-CD2 3.24Å; A90-F430 WeakPolarHBondContact O-CD2 3.32Å; V91-F430 HydrophobicContact CG2-CE2 4.34Å; S426-F430 WeakPolarHBondContact O-CB 3.21Å; S426-F430 PolarHBondContact O-N 3.08Å; F427-F430 WeakPolarHBondContact O-CB 3.37Å; F427-F430 PolarHBondContact O-N 2.97Å; F430-T432 PolarHBondContact O-N 3.19Å; F430-K433 PolarHBondContact O-N 3.25Å; F430-F434 VanDerWaalsContact O-CB 3.28Å; F430-F434 WeakPolarHBondContact O-CB 3.34Å; F430-F434 PolarHBondContact O-N 3.15Å
431	F	86.5	Confident	84.5	Confident	50 Å²	50	32.9 Å²	32.9	22%	0.219	18%	0.177	C	C	.	.	H	α-helix	trans	-66	-38.8	-176.7	-84.5	-58.5	0	0	0	112.8	M286 V295 L299 F427 Y428 V429 A435	M286-F431 HydrophobicContact CE-CZ 4.27Å; M286-F431 HydrophobicContact SD-CE2 4.46Å; M286-F431 HydrophobicContact SD-CZ 4.21Å; V295-F431 HydrophobicContact CG1-CB 4.29Å; V295-F431 HydrophobicContact CG1-CD2 3.99Å; V295-F431 HydrophobicContact CG1-CG 4.34Å; L299-F431 HydrophobicContact CD1-CB 4.08Å; L299-F431 HydrophobicContact CD1-CD1 4.25Å; L299-F431 HydrophobicContact CD1-CG 4.45Å; F427-F431 HydrophobicContact CD1-CE2 4.18Å; F427-F431 WeakPolarHBondContact O-CD2 3.42Å; F427-F431 PolarHBondContact O-N 3.07Å; Y428-F431 PolarHBondContact O-N 2.63Å; V429-F431 PolarHBondContact O-N 2.86Å; F431-A435 VanDerWaalsContact O-CB 3.23Å; F431-A435 WeakPolarHBondContact O-CB 2.97Å; F431-A435 PolarHBondContact O-N 3.32Å
432	T	87.7	Confident	85.4	Confident	27 Å²	27	33.5 Å²	33.5	17%	0.166	18%	0.182	C	C	.	.	H	α-helix	trans	-69.7	-40.9	177.8	49.4	0	0	0	0	112.3	Y428 V429 F430 A435 S436	Y428-T432 HydrophobicContact CD2-CG2 4.34Å; Y428-T432 HydrophobicContact CE1-CG2 4.12Å; Y428-T432 HydrophobicContact CE2-CG2 3.77Å; Y428-T432 WeakPolarHBondContact O-CG2 3.45Å; Y428-T432 PolarHBondContact O-N 3.24Å; Y428-T432 PolarHBondContact O-OG1 3.49Å; V429-T432 WeakPolarHBondContact CA-OG1 3.19Å; V429-T432 PolarHBondContact O-N 3.03Å; V429-T432 PolarHBondContact O-OG1 3.05Å; F430-T432 PolarHBondContact O-N 3.19Å; T432-A435 PolarHBondContact O-N 2.89Å; T432-S436 PolarHBondContact O-N 3.32Å
433	K	88.3	Confident	86.4	Confident	14 Å²	14	30.3 Å²	30.3	6%	0.061	16%	0.156	C	C	.	.	H	α-helix	trans	-65.2	-42.8	173.5	-75.7	-172.8	166.1	-168.6	0	112.3	Y52 D89 A90 D93 V429 F430 S436 G437	Y52-K433 WeakPolarHBondContact OH-CE 3.5Å; Y52-K433 PolarHBondContact OH-NZ 3.25Å; D89-K433 IonicContact OD1-NZ 2.62Å; D89-K433 PolarHBondContact OD1-NZ 3.05Å; D89-K433 WeakPolarHBondContact OD2-CD 3.24Å; D89-K433 VanDerWaalsContact OD2-CE 3.22Å; D89-K433 WeakPolarHBondContact OD2-CE 3.46Å; D89-K433 IonicContact OD2-NZ 3.08Å; D89-K433 PolarHBondContact OD2-NZ 3.15Å; A90-K433 HydrophobicContact CB-CB 3.85Å; D93-K433 VanDerWaalsContact CG-NZ 3.31Å; D93-K433 IonicContact OD1-NZ 2.79Å; D93-K433 PolarHBondContact OD1-NZ 3.29Å; D93-K433 WeakPolarHBondContact OD2-CD 3.49Å; D93-K433 VanDerWaalsContact OD2-CE 3.28Å; D93-K433 WeakPolarHBondContact OD2-CE 3.39Å; D93-K433 IonicContact OD2-NZ 2.77Å; D93-K433 PolarHBondContact OD2-NZ 2.87Å; V429-K433 HydrophobicContact CG1-CD 4.09Å; V429-K433 HydrophobicContact CG1-CG 4.32Å; V429-K433 WeakPolarHBondContact O-CB 3.34Å; V429-K433 WeakPolarHBondContact O-CG 3.05Å; V429-K433 PolarHBondContact O-N 3.25Å; F430-K433 PolarHBondContact O-N 3.25Å; K433-S436 WeakPolarHBondContact O-CB 3.43Å; K433-S436 PolarHBondContact O-N 3.36Å; K433-G437 PolarHBondContact O-N 3.46Å
434	F	88.3	Confident	87	Confident	83 Å²	83	28.1 Å²	28.1	36%	0.364	15%	0.145	S	C	.	.	H	α-helix	trans	-61.5	-46.3	175.5	-177.3	-102.7	0	0	0	111.4	A90 F430 S436 G437 V438	A90-F434 HydrophobicContact CB-CB 4.18Å; F430-F434 VanDerWaalsContact O-CB 3.28Å; F430-F434 WeakPolarHBondContact O-CB 3.34Å; F430-F434 PolarHBondContact O-N 3.15Å; F434-S436 VanDerWaalsContact C-N 3.32Å; F434-S436 PolarHBondContact O-N 3.48Å; F434-G437 PolarHBondContact O-N 2.81Å; F434-G437 VanDerWaalsContact O-N 3.16Å; F434-V438 HydrophobicContact CD1-CG2 4.09Å; F434-V438 HydrophobicContact CE1-CG2 3.69Å; F434-V438 HydrophobicContact CE2-CG2 4.41Å; F434-V438 HydrophobicContact CZ-CG2 3.87Å; F434-V438 WeakPolarHBondContact O-CG2 3.48Å; F434-V438 PolarHBondContact O-N 3.41Å
435	A	89.7	Confident	87.6	Confident	5 Å²	5	30.7 Å²	30.7	4%	0.041	16%	0.158	C	C	.	.	H	α-helix	trans	-58.1	-43.3	174.8	0	0	0	0	0	111.9	L299 L303 F431 T432 G437 V438 S439	L299-A435 HydrophobicContact CD2-CB 4.28Å; L299-A435 HydrophobicContact CG-CB 4.01Å; L303-A435 HydrophobicContact CD1-CB 3.93Å; L303-A435 WeakPolarHBondContact CD1-O 3.42Å; F431-A435 VanDerWaalsContact O-CB 3.23Å; F431-A435 WeakPolarHBondContact O-CB 2.97Å; F431-A435 PolarHBondContact O-N 3.32Å; T432-A435 PolarHBondContact O-N 2.89Å; A435-G437 VanDerWaalsContact C-N 3.35Å; A435-G437 PolarHBondContact O-N 3.27Å; A435-V438 PolarHBondContact O-N 2.98Å; A435-S439 WeakPolarHBondContact O-CB 3.33Å; A435-S439 PolarHBondContact O-N 3.44Å
436	S	89.4	Confident	88.1	Confident	2 Å²	2	29.1 Å²	29.1	1%	0.014	16%	0.158	C	C	.	.	H	α-helix	trans	-56.4	-46.9	174.2	-179	0	0	0	0	111.8	R86 M306 T432 K433 F434 S439 L440	R86-S436 PolarHBondContact NH1-OG 2.89Å; R86-S436 VanDerWaalsContact NH1-OG 3.14Å; M306-S436 PolarHBondContact SD-OG 3.34Å; M306-S436 VanDerWaalsContact SD-OG 3.4Å; T432-S436 PolarHBondContact O-N 3.32Å; K433-S436 WeakPolarHBondContact O-CB 3.43Å; K433-S436 PolarHBondContact O-N 3.36Å; F434-S436 VanDerWaalsContact C-N 3.32Å; F434-S436 PolarHBondContact O-N 3.48Å; S436-S439 WeakPolarHBondContact O-CB 3.29Å; S436-S439 PolarHBondContact O-N 2.92Å; S436-L440 WeakPolarHBondContact O-CD1 3.31Å; S436-L440 PolarHBondContact O-N 3.47Å
437	G	89.5	Confident	88.7	Confident	1 Å²	1	26.2 Å²	26.2	1%	0.01	14%	0.137	C	C	.	.	H	α-helix	trans	-61.3	-46.1	176.4	0	0	0	0	0	113.8	K433 F434 A435 S439 L440 G441	K433-G437 PolarHBondContact O-N 3.46Å; F434-G437 PolarHBondContact O-N 2.81Å; F434-G437 VanDerWaalsContact O-N 3.16Å; A435-G437 VanDerWaalsContact C-N 3.35Å; A435-G437 PolarHBondContact O-N 3.27Å; G437-S439 VanDerWaalsContact C-N 3.33Å; G437-S439 PolarHBondContact O-N 2.91Å; G437-L440 PolarHBondContact O-N 3.13Å; G437-G441 PolarHBondContact O-N 3.33Å
438	V	90.8	Very high	89.1	Confident	39 Å²	39	27.9 Å²	27.9	24%	0.236	15%	0.147	C	C	.	.	H	α-helix	trans	-58.9	-45	175.1	173.3	0	0	0	0	110.8	F83 F434 A435 I442	F83-V438 HydrophobicContact CE2-CG2 3.88Å; F434-V438 HydrophobicContact CD1-CG2 4.09Å; F434-V438 HydrophobicContact CE1-CG2 3.69Å; F434-V438 HydrophobicContact CE2-CG2 4.41Å; F434-V438 HydrophobicContact CZ-CG2 3.87Å; F434-V438 WeakPolarHBondContact O-CG2 3.48Å; F434-V438 PolarHBondContact O-N 3.41Å; A435-V438 PolarHBondContact O-N 2.98Å; V438-I442 HydrophobicContact CG1-CD1 3.48Å; V438-I442 VanDerWaalsContact CG1-CD1 3.48Å; V438-I442 HydrophobicContact CG1-CG1 4.23Å; V438-I442 WeakPolarHBondContact O-CB 3.35Å; V438-I442 VanDerWaalsContact O-CG1 3.28Å; V438-I442 WeakPolarHBondContact O-CG1 3.47Å; V438-I442 PolarHBondContact O-N 3.25Å
439	S	91.2	Very high	89.4	Confident	3 Å²	3	35.2 Å²	35.2	2%	0.021	18%	0.18	C	C	.	.	H	α-helix	trans	-56.9	-56.4	177	150.9	0	0	0	0	111.9	L303 L307 A435 S436 G437 G441 S443	L303-S439 VanDerWaalsContact CD1-CB 3.48Å; L307-S439 VanDerWaalsContact CA-OG 3.27Å; L307-S439 WeakPolarHBondContact CA-OG 3.36Å; L307-S439 WeakPolarHBondContact CD2-O 3.23Å; L307-S439 WeakPolarHBondContact CD2-OG 3.38Å; L307-S439 WeakPolarHBondContact CG-OG 3.15Å; L307-S439 PolarHBondContact N-OG 3.05Å; L307-S439 VanDerWaalsContact N-OG 3.15Å; A435-S439 WeakPolarHBondContact O-CB 3.33Å; A435-S439 PolarHBondContact O-N 3.44Å; S436-S439 WeakPolarHBondContact O-CB 3.29Å; S436-S439 PolarHBondContact O-N 2.92Å; G437-S439 VanDerWaalsContact C-N 3.33Å; G437-S439 PolarHBondContact O-N 2.91Å; S439-G441 PolarHBondContact O-N 3.02Å; S439-S443 WeakPolarHBondContact O-CB 3.21Å; S439-S443 PolarHBondContact O-N 2.87Å
440	L	87.3	Confident	89.7	Confident	7 Å²	7	34.4 Å²	34.4	4%	0.037	18%	0.176	C	C	.	.	H	α-helix	trans	-63.2	-41.3	-178.1	-83.4	139.3	0	0	0	112.2	L82 R86 S436 G437 T444	L82-L440 HydrophobicContact CB-CB 4.25Å; L82-L440 HydrophobicContact CD1-CD2 4.24Å; R86-L440 HydrophobicContact CG-CD1 4.42Å; S436-L440 WeakPolarHBondContact O-CD1 3.31Å; S436-L440 PolarHBondContact O-N 3.47Å; G437-L440 PolarHBondContact O-N 3.13Å; L440-T444 WeakPolarHBondContact O-CB 3.33Å; L440-T444 PolarHBondContact O-N 3.07Å; L440-T444 PolarHBondContact O-OG1 2.98Å
441	G	90.2	Very high	89.7	Confident	8 Å²	8	33.6 Å²	33.6	8%	0.082	18%	0.183	C	C	.	.	H	α-helix	trans	-62.8	-56	177.4	0	0	0	0	0	112.9	S79 G437 S439 S443 T444 L445	S79-G441 WeakPolarHBondContact CB-O 3.47Å; G437-G441 PolarHBondContact O-N 3.33Å; S439-G441 PolarHBondContact O-N 3.02Å; G441-S443 PolarHBondContact O-N 2.84Å; G441-T444 PolarHBondContact O-N 3.31Å; G441-L445 WeakPolarHBondContact O-CB 3.4Å; G441-L445 PolarHBondContact O-N 3.3Å
442	I	90.6	Very high	89.7	Confident	101 Å²	101	31.9 Å²	31.9	52%	0.518	18%	0.175	S	C	.	.	H	α-helix	trans	-59.9	-40.1	178.4	-68.1	174.8	0	0	0	110.5	V438 L445 S446	V438-I442 HydrophobicContact CG1-CD1 3.48Å; V438-I442 VanDerWaalsContact CG1-CD1 3.48Å; V438-I442 HydrophobicContact CG1-CG1 4.23Å; V438-I442 WeakPolarHBondContact O-CB 3.35Å; V438-I442 VanDerWaalsContact O-CG1 3.28Å; V438-I442 WeakPolarHBondContact O-CG1 3.47Å; V438-I442 PolarHBondContact O-N 3.25Å; I442-L445 PolarHBondContact O-N 2.94Å; I442-S446 WeakPolarHBondContact O-CB 3.19Å; I442-S446 PolarHBondContact O-N 2.98Å; I442-S446 PolarHBondContact O-OG 3.44Å
443	S	91.4	Very high	89.5	Confident	0 Å²	0	34.8 Å²	34.8	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-62.8	-47.7	-179.7	-168.4	0	0	0	0	112.4	N311 S439 G441 S446 L447 L470	N311-S443 PolarHBondContact ND2-OG 3.06Å; N311-S443 PolarHBondContact OD1-OG 3.2Å; S439-S443 WeakPolarHBondContact O-CB 3.21Å; S439-S443 PolarHBondContact O-N 2.87Å; G441-S443 PolarHBondContact O-N 2.84Å; S443-S446 WeakPolarHBondContact O-CB 3.11Å; S443-S446 PolarHBondContact O-N 2.95Å; S443-L447 PolarHBondContact O-N 3.23Å; S443-L470 WeakPolarHBondContact OG-CD1 3.4Å
444	T	90.4	Very high	89.2	Confident	0 Å²	0	35.7 Å²	35.7	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-71	-35.7	-178.5	-51.2	0	0	0	0	111.2	Q64 P75 A78 L440 G441 S446 L447 D448	Q64-T444 PolarHBondContact NE2-OG1 3.05Å; P75-T444 HydrophobicContact CB-CG2 4.25Å; P75-T444 VanDerWaalsContact O-CG2 3.29Å; P75-T444 WeakPolarHBondContact O-CG2 3.46Å; A78-T444 HydrophobicContact CB-CG2 3.93Å; L440-T444 WeakPolarHBondContact O-CB 3.33Å; L440-T444 PolarHBondContact O-N 3.07Å; L440-T444 PolarHBondContact O-OG1 2.98Å; G441-T444 PolarHBondContact O-N 3.31Å; T444-S446 VanDerWaalsContact C-N 3.3Å; T444-S446 PolarHBondContact O-N 2.9Å; T444-L447 WeakPolarHBondContact O-CB 3.36Å; T444-L447 PolarHBondContact O-N 3.1Å; T444-D448 PolarHBondContact O-N 3.4Å; T444-D448 VanDerWaalsContact O-N 3.15Å
445	L	92.7	Very high	88.6	Confident	55 Å²	55	32.4 Å²	32.4	29%	0.288	18%	0.181	S	C	.	.	H	α-helix	trans	-63.3	-36.8	171.9	-175.9	66.2	0	0	0	112	F76 G441 I442 L447 D448 F449	F76-L445 HydrophobicContact CD2-CD1 3.81Å; F76-L445 HydrophobicContact CE2-CD1 4.25Å; G441-L445 WeakPolarHBondContact O-CB 3.4Å; G441-L445 PolarHBondContact O-N 3.3Å; I442-L445 PolarHBondContact O-N 2.94Å; L445-L447 VanDerWaalsContact C-N 3.27Å; L445-L447 PolarHBondContact O-N 3.25Å; L445-D448 VanDerWaalsContact O-CB 3.24Å; L445-D448 WeakPolarHBondContact O-CB 3.49Å; L445-D448 PolarHBondContact O-N 3.49Å; L445-D448 VanDerWaalsContact O-N 3.16Å; L445-F449 HydrophobicContact CD1-CE2 4.03Å; L445-F449 HydrophobicContact CD1-CZ 4.46Å; L445-F449 HydrophobicContact CD2-CE2 4.09Å; L445-F449 HydrophobicContact CG-CD2 4.17Å; L445-F449 HydrophobicContact CG-CE2 3.71Å; L445-F449 VanDerWaalsContact O-CD2 3.3Å; L445-F449 WeakPolarHBondContact O-CD2 3.2Å; L445-F449 PolarHBondContact O-N 3.46Å
446	S	92.4	Very high	87.8	Confident	38 Å²	38	32.4 Å²	32.4	27%	0.266	18%	0.182	S	C	.	.	H	α-helix	trans	-64	-33.7	175.1	-57.4	0	0	0	0	111.9	I442 S443 T444 A450	I442-S446 WeakPolarHBondContact O-CB 3.19Å; I442-S446 PolarHBondContact O-N 2.98Å; I442-S446 PolarHBondContact O-OG 3.44Å; S443-S446 WeakPolarHBondContact O-CB 3.11Å; S443-S446 PolarHBondContact O-N 2.95Å; T444-S446 VanDerWaalsContact C-N 3.3Å; T444-S446 PolarHBondContact O-N 2.9Å; S446-A450 WeakPolarHBondContact O-CB 3.45Å; S446-A450 PolarHBondContact O-N 3.36Å; S446-A450 VanDerWaalsContact O-N 3.09Å
447	L	89.6	Confident	87	Confident	0 Å²	0	34.9 Å²	34.9	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-69.6	-32.4	173.9	-65.6	173	0	0	0	112.7	L314 S443 T444 L445 A450 G451 Y452 V463 T466 L467 L470	L314-L447 HydrophobicContact CD1-CD1 3.88Å; S443-L447 PolarHBondContact O-N 3.23Å; T444-L447 WeakPolarHBondContact O-CB 3.36Å; T444-L447 PolarHBondContact O-N 3.1Å; L445-L447 VanDerWaalsContact C-N 3.27Å; L445-L447 PolarHBondContact O-N 3.25Å; L447-A450 PolarHBondContact O-N 2.88Å; L447-G451 PolarHBondContact O-N 2.81Å; L447-Y452 WeakPolarHBondContact O-CB 3.28Å; L447-Y452 PolarHBondContact O-N 2.79Å; L447-V463 HydrophobicContact CD2-CG1 4.42Å; L447-T466 HydrophobicContact CD2-CG2 4.11Å; L447-L467 HydrophobicContact CD1-CD2 4.34Å; L447-L467 HydrophobicContact CD2-CD2 3.69Å; L447-L467 HydrophobicContact CD2-CG 3.81Å; L447-L470 HydrophobicContact CD2-CD1 4.37Å; L447-L470 HydrophobicContact CG-CD1 4.46Å
448	D	89.6	Confident	86.3	Confident	53 Å²	53	39 Å²	39	28%	0.283	23%	0.228	S	C	.	.	H	α-helix	trans	-60.9	-51.5	173	-161.7	66.7	0	0	0	110.8	P75 F76 T444 L445 A450 G451	P75-D448 HydrophobicContact CB-CB 3.82Å; F76-D448 PolarHBondContact N-OD1 3.18Å; T444-D448 PolarHBondContact O-N 3.4Å; T444-D448 VanDerWaalsContact O-N 3.15Å; L445-D448 VanDerWaalsContact O-CB 3.24Å; L445-D448 WeakPolarHBondContact O-CB 3.49Å; L445-D448 PolarHBondContact O-N 3.49Å; L445-D448 VanDerWaalsContact O-N 3.16Å; D448-A450 PolarHBondContact O-N 2.88Å; D448-G451 PolarHBondContact O-N 2.95Å
449	F	91.4	Very high	86	Confident	168 Å²	168	38.3 Å²	38.3	74%	0.737	22%	0.222	S	C	*	.	H	α-helix	trans	-63.4	-29.8	177.4	-71.3	-56.2	0	0	0	113.3	L445 G451	L445-F449 HydrophobicContact CD1-CE2 4.03Å; L445-F449 HydrophobicContact CD1-CZ 4.46Å; L445-F449 HydrophobicContact CD2-CE2 4.09Å; L445-F449 HydrophobicContact CG-CD2 4.17Å; L445-F449 HydrophobicContact CG-CE2 3.71Å; L445-F449 VanDerWaalsContact O-CD2 3.3Å; L445-F449 WeakPolarHBondContact O-CD2 3.2Å; L445-F449 PolarHBondContact O-N 3.46Å; F449-G451 PolarHBondContact O-N 3.44Å
450	A	90	Very high	85.9	Confident	14 Å²	14	39.9 Å²	39.9	12%	0.116	23%	0.231	C	C	.	.	T	Hydrogen-bonded Turn	trans	-74.7	-9.9	174	0	0	0	0	0	113.4	S446 L447 D448 V463 T466	S446-A450 WeakPolarHBondContact O-CB 3.45Å; S446-A450 PolarHBondContact O-N 3.36Å; S446-A450 VanDerWaalsContact O-N 3.09Å; L447-A450 PolarHBondContact O-N 2.88Å; D448-A450 PolarHBondContact O-N 2.88Å; A450-V463 HydrophobicContact CB-CG2 3.87Å; A450-V463 VanDerWaalsContact O-CG2 3.29Å; A450-V463 WeakPolarHBondContact O-CG2 3.43Å; A450-T466 HydrophobicContact CB-CG2 4.26Å; A450-T466 WeakPolarHBondContact CB-OG1 3.28Å
451	G	86.9	Confident	85.9	Confident	38 Å²	38	48 Å²	48	39%	0.392	27%	0.266	S	S	.	.	T	Hydrogen-bonded Turn	trans	77.8	41.6	-179.5	0	0	0	0	0	113.5	L447 D448 F449 I453	L447-G451 PolarHBondContact O-N 2.81Å; D448-G451 PolarHBondContact O-N 2.95Å; F449-G451 PolarHBondContact O-N 3.44Å; G451-I453 PolarHBondContact O-N 3.28Å
452	Y	86.9	Confident	85.9	Confident	13 Å²	13	53.1 Å²	53.1	5%	0.051	29%	0.288	C	S	.	.			trans	-55.1	121.7	177.9	-176.5	-89.7	0	0	0	112.1	L68 P75 A318 L447 V463	L68-Y452 HydrophobicContact CB-CE1 4.22Å; L68-Y452 HydrophobicContact CD1-CD1 4.44Å; L68-Y452 HydrophobicContact CD1-CE1 4.06Å; P75-Y452 HydrophobicContact CG-CD1 4.22Å; A318-Y452 HydrophobicContact CB-CE2 4.45Å; L447-Y452 WeakPolarHBondContact O-CB 3.28Å; L447-Y452 PolarHBondContact O-N 2.79Å; Y452-V463 HydrophobicContact CD2-CG1 3.69Å; Y452-V463 HydrophobicContact CE2-CG1 4.42Å
453	I	83.4	Confident	85.9	Confident	88 Å²	88	48.3 Å²	48.3	45%	0.451	26%	0.264	S	S	.	.			trans	-93.7	109.2	179.9	-55.8	175.6	0	0	0	108.9	G451 R455 G456 Q459 P460	G451-I453 PolarHBondContact O-N 3.28Å; I453-R455 PolarHBondContact O-N 2.75Å; I453-G456 PolarHBondContact O-N 3.47Å; I453-G456 VanDerWaalsContact O-N 3.1Å; I453-Q459 PolarHBondContact O-NE2 3.22Å; I453-P460 HydrophobicContact CD1-CG 4.06Å; I453-P460 HydrophobicContact CG1-CG 4.29Å
454	T	81.4	Confident	85.8	Confident	34 Å²	34	50.7 Å²	50.7	21%	0.209	28%	0.276	C	S	.	.	T	Hydrogen-bonded Turn	trans	-53.5	124	177	-63.9	0	0	0	0	112	L68 Q72 G456	L68-T454 WeakPolarHBondContact O-CG2 3.4Å; Q72-T454 HydrophobicContact CB-CG2 4.5Å; T454-G456 PolarHBondContact O-N 2.87Å; T454-G456 VanDerWaalsContact O-N 3.17Å
455	R	75.2	Confident	85.8	Confident	13 Å²	13	56.2 Å²	56.2	5%	0.049	31%	0.305	C	S	.	.	T	Hydrogen-bonded Turn	trans	59	13.7	-177.2	-55.1	-173.8	70.6	-167.2	-6.5	117	D69 P209 C210 L211 I453	D69-R455 HydrophobicContact CB-CG 4.15Å; D69-R455 VanDerWaalsContact O-CD 3.22Å; D69-R455 WeakPolarHBondContact O-CD 3.49Å; D69-R455 WeakPolarHBondContact O-CG 3.33Å; D69-R455 PolarHBondContact OD1-N 2.84Å; P209-R455 PolarHBondContact O-NH2 3.44Å; C210-R455 WeakPolarHBondContact CA-O 3.43Å; L211-R455 HydrophobicContact CD1-CB 4.36Å; L211-R455 PolarHBondContact N-O 3.47Å; I453-R455 PolarHBondContact O-N 2.75Å
456	G	72.6	Confident	85.8	Confident	6 Å²	6	55 Å²	55	6%	0.062	30%	0.301	C	S	.	.	B	Isolated β-bridge	trans	-63	135.6	176.9	0	0	0	0	0	112.8	R323 I453 T454 S458	R323-G456 PolarHBondContact NH2-O 3.35Å; I453-G456 PolarHBondContact O-N 3.47Å; I453-G456 VanDerWaalsContact O-N 3.1Å; T454-G456 PolarHBondContact O-N 2.87Å; T454-G456 VanDerWaalsContact O-N 3.17Å; G456-S458 VanDerWaalsContact C-N 3.28Å
457	C	72.5	Confident	85.7	Confident	54 Å²	54	53.2 Å²	53.2	37%	0.365	29%	0.288	S	S	.	.	S	Bend	trans	-65	-34	171.9	-73.6	0	0	0	0	112.4	C210 L211 R323	C210-C457 HydrophobicContact CB-CB 3.83Å; C210-C457 WeakPolarHBondContact CB-SG 3.46Å; C210-C457 PolarHBondContact O-SG 2.86Å; C210-C457 WeakPolarHBondContact SG-CA 3.48Å; C210-C457 WeakPolarHBondContact SG-CB 3.29Å; C210-C457 CovalentContact SG-SG 2.03Å; C210-C457 PolarHBondContact SG-SG 3.38Å; L211-C457 PolarHBondContact O-N 3.35Å; L211-C457 PolarHBondContact O-SG 3.05Å; L211-C457 VanDerWaalsContact O-SG 3.42Å; R323-C457 PolarHBondContact NH2-O 2.96Å
458	S	76.1	Confident	85.8	Confident	88 Å²	88	56.3 Å²	56.3	62%	0.615	30%	0.301	S	S	*	.	S	Bend	trans	-121.8	134.5	172.9	-171.3	0	0	0	0	108.5	G456	G456-S458 VanDerWaalsContact C-N 3.28Å
459	Q	84.6	Confident	86	Confident	24 Å²	24	58.2 Å²	58.2	11%	0.112	31%	0.311	C	S	.	.			trans	-94.9	157.2	171	-65.8	-60.2	-27.6	0	0	110.5	A318 I453 V463	A318-Q459 HydrophobicContact CB-CG 4Å; I453-Q459 PolarHBondContact O-NE2 3.22Å; Q459-V463 HydrophobicContact CB-CB 4.08Å; Q459-V463 HydrophobicContact CB-CG1 4.01Å; Q459-V463 HydrophobicContact CG-CG1 4.2Å
460	P	87.6	Confident	86	Confident	35 Å²	35	50.7 Å²	50.7	23%	0.227	28%	0.278	C	S	.	.			trans	-55.8	155.6	167.5	-22.3	32.3	0	0	0	112.3	I453 E462 V463 D464	I453-P460 HydrophobicContact CD1-CG 4.06Å; I453-P460 HydrophobicContact CG1-CG 4.29Å; P460-E462 VanDerWaalsContact CB-OE2 3.28Å; P460-E462 WeakPolarHBondContact CB-OE2 3.26Å; P460-E462 PolarHBondContact O-N 2.85Å; P460-V463 HydrophobicContact CB-CG2 4.19Å; P460-V463 HydrophobicContact CG-CG2 4.09Å; P460-V463 PolarHBondContact O-N 3.37Å; P460-D464 PolarHBondContact O-N 3.23Å
461	K	87.6	Confident	86.1	Confident	177 Å²	177	50 Å²	50	77%	0.77	27%	0.273	S	S	*	.	H	α-helix	trans	-65.1	-30.6	179.5	-68.2	-178.7	-179.2	176.5	0	111.5	V463 D464 L465	K461-V463 VanDerWaalsContact C-N 3.33Å; K461-D464 PolarHBondContact O-N 3.19Å; K461-L465 PolarHBondContact O-N 3.3Å
462	E	91.5	Very high	86.3	Confident	116 Å²	116	48.8 Å²	48.8	54%	0.542	26%	0.258	S	S	.	.	H	α-helix	trans	-63.1	-39.6	177.4	-62.4	72.2	-159	0	0	110.9	P460 T466	P460-E462 VanDerWaalsContact CB-OE2 3.28Å; P460-E462 WeakPolarHBondContact CB-OE2 3.26Å; P460-E462 PolarHBondContact O-N 2.85Å; E462-T466 WeakPolarHBondContact O-CB 3.23Å; E462-T466 PolarHBondContact O-N 3.28Å; E462-T466 PolarHBondContact O-OG1 3.07Å
463	V	90	Very high	86.6	Confident	0 Å²	0	50.6 Å²	50.6	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-69.7	-42.9	176.6	176.2	0	0	0	0	111.4	L447 A450 Y452 Q459 P460 K461 L465 T466 L467	L447-V463 HydrophobicContact CD2-CG1 4.42Å; A450-V463 HydrophobicContact CB-CG2 3.87Å; A450-V463 VanDerWaalsContact O-CG2 3.29Å; A450-V463 WeakPolarHBondContact O-CG2 3.43Å; Y452-V463 HydrophobicContact CD2-CG1 3.69Å; Y452-V463 HydrophobicContact CE2-CG1 4.42Å; Q459-V463 HydrophobicContact CB-CB 4.08Å; Q459-V463 HydrophobicContact CB-CG1 4.01Å; Q459-V463 HydrophobicContact CG-CG1 4.2Å; P460-V463 HydrophobicContact CB-CG2 4.19Å; P460-V463 HydrophobicContact CG-CG2 4.09Å; P460-V463 PolarHBondContact O-N 3.37Å; K461-V463 VanDerWaalsContact C-N 3.33Å; V463-L465 VanDerWaalsContact C-N 3.34Å; V463-L465 PolarHBondContact O-N 3.07Å; V463-T466 PolarHBondContact O-N 3.24Å; V463-L467 HydrophobicContact CG1-CD1 4.04Å; V463-L467 HydrophobicContact CG1-CG 4.47Å; V463-L467 WeakPolarHBondContact O-CG 3.37Å; V463-L467 PolarHBondContact O-N 2.93Å
464	D	88.4	Confident	87.1	Confident	50 Å²	50	47.7 Å²	47.7	27%	0.267	27%	0.265	S	S	.	.	H	α-helix	trans	-58.5	-45.9	174.8	172.2	80.1	0	0	0	111.2	T319 P460 K461 K468	T319-D464 WeakPolarHBondContact CG2-OD1 3.24Å; P460-D464 PolarHBondContact O-N 3.23Å; K461-D464 PolarHBondContact O-N 3.19Å; D464-K468 VanDerWaalsContact O-CG 3.27Å; D464-K468 WeakPolarHBondContact O-CG 3.36Å; D464-K468 PolarHBondContact O-N 3.43Å; D464-K468 VanDerWaalsContact O-N 3.07Å; D464-K468 WeakPolarHBondContact OD1-CE 3.49Å; D464-K468 IonicContact OD1-NZ 3.02Å; D464-K468 PolarHBondContact OD1-NZ 2.99Å; D464-K468 WeakPolarHBondContact OD2-CE 3.06Å; D464-K468 IonicContact OD2-NZ 2.69Å; D464-K468 PolarHBondContact OD2-NZ 2.97Å
465	L	91.5	Very high	87.7	Confident	116 Å²	116	46 Å²	46	61%	0.607	26%	0.255	S	S	*	.	H	α-helix	trans	-62.5	-44.1	175.2	-176.9	67.3	0	0	0	111.8	K461 V463 K468 L469	K461-L465 PolarHBondContact O-N 3.3Å; V463-L465 VanDerWaalsContact C-N 3.34Å; V463-L465 PolarHBondContact O-N 3.07Å; L465-K468 PolarHBondContact O-N 3.22Å; L465-L469 WeakPolarHBondContact O-CB 3.44Å; L465-L469 PolarHBondContact O-N 3.45Å
466	T	92.9	Very high	88.7	Confident	31 Å²	31	46.4 Å²	46.4	19%	0.19	26%	0.258	C	S	.	.	H	α-helix	trans	-63	-45.6	-179.2	-60.2	0	0	0	0	111.2	L447 A450 E462 V463 K468 L469 L470	L447-T466 HydrophobicContact CD2-CG2 4.11Å; A450-T466 HydrophobicContact CB-CG2 4.26Å; A450-T466 WeakPolarHBondContact CB-OG1 3.28Å; E462-T466 WeakPolarHBondContact O-CB 3.23Å; E462-T466 PolarHBondContact O-N 3.28Å; E462-T466 PolarHBondContact O-OG1 3.07Å; V463-T466 PolarHBondContact O-N 3.24Å; T466-K468 PolarHBondContact O-N 3Å; T466-L469 PolarHBondContact O-N 3.13Å; T466-L470 HydrophobicContact CG2-CD1 3.73Å; T466-L470 HydrophobicContact CG2-CG 4.39Å; T466-L470 WeakPolarHBondContact O-CB 3.22Å; T466-L470 WeakPolarHBondContact O-CD1 3.38Å; T466-L470 VanDerWaalsContact O-CG 3.24Å; T466-L470 WeakPolarHBondContact O-CG 3.33Å; T466-L470 PolarHBondContact O-N 3.5Å
467	L	90.2	Very high	89.8	Confident	0 Å²	0	50.1 Å²	50.1	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-63.8	-40.6	176.5	-74.7	169.6	0	0	0	112.2	L314 F315 A318 L447 V463 L469 L470 V471	L314-L467 HydrophobicContact CB-CD2 4.22Å; F315-L467 HydrophobicContact CD2-CB 4.1Å; A318-L467 HydrophobicContact CB-CD1 4.01Å; L447-L467 HydrophobicContact CD1-CD2 4.34Å; L447-L467 HydrophobicContact CD2-CD2 3.69Å; L447-L467 HydrophobicContact CD2-CG 3.81Å; V463-L467 HydrophobicContact CG1-CD1 4.04Å; V463-L467 HydrophobicContact CG1-CG 4.47Å; V463-L467 WeakPolarHBondContact O-CG 3.37Å; V463-L467 PolarHBondContact O-N 2.93Å; L467-L469 VanDerWaalsContact C-N 3.3Å; L467-L469 PolarHBondContact O-N 2.99Å; L467-L470 PolarHBondContact O-N 3.31Å; L467-V471 WeakPolarHBondContact O-CB 2.97Å; L467-V471 WeakPolarHBondContact O-CG2 3.27Å; L467-V471 PolarHBondContact O-N 2.98Å
468	K	91.3	Very high	90.8	Very high	64 Å²	64	48.9 Å²	48.9	28%	0.278	27%	0.269	S	S	.	.	H	α-helix	trans	-61.3	-39.3	174.2	-73.6	171.3	178.9	164.6	0	112.1	F315 V372 D464 L465 T466 S472	F315-K468 HydrophobicContact CE2-CG 3.91Å; V372-K468 HydrophobicContact CG1-CB 4.11Å; V372-K468 HydrophobicContact CG1-CD 3.89Å; V372-K468 HydrophobicContact CG1-CG 3.79Å; V372-K468 HydrophobicContact CG2-CB 4.37Å; V372-K468 HydrophobicContact CG2-CG 4.3Å; D464-K468 VanDerWaalsContact O-CG 3.27Å; D464-K468 WeakPolarHBondContact O-CG 3.36Å; D464-K468 PolarHBondContact O-N 3.43Å; D464-K468 VanDerWaalsContact O-N 3.07Å; D464-K468 WeakPolarHBondContact OD1-CE 3.49Å; D464-K468 IonicContact OD1-NZ 3.02Å; D464-K468 PolarHBondContact OD1-NZ 2.99Å; D464-K468 WeakPolarHBondContact OD2-CE 3.06Å; D464-K468 IonicContact OD2-NZ 2.69Å; D464-K468 PolarHBondContact OD2-NZ 2.97Å; L465-K468 PolarHBondContact O-N 3.22Å; T466-K468 PolarHBondContact O-N 3Å; K468-S472 VanDerWaalsContact O-CB 3.3Å; K468-S472 WeakPolarHBondContact O-CB 3.28Å; K468-S472 PolarHBondContact O-N 3.35Å; K468-S472 VanDerWaalsContact O-N 3.09Å
469	L	93.3	Very high	91.7	Very high	93 Å²	93	44.7 Å²	44.7	49%	0.487	24%	0.24	S	C	.	.	I	π-helix	trans	-67.1	-43.7	176.9	-171.9	147	0	0	0	111.5	L465 T466 L467 A473 A474	L465-L469 WeakPolarHBondContact O-CB 3.44Å; L465-L469 PolarHBondContact O-N 3.45Å; T466-L469 PolarHBondContact O-N 3.13Å; L467-L469 VanDerWaalsContact C-N 3.3Å; L467-L469 PolarHBondContact O-N 2.99Å; L469-A473 HydrophobicContact CG-CB 4.37Å; L469-A473 PolarHBondContact O-N 3.21Å; L469-A474 HydrophobicContact CD2-CB 4.11Å; L469-A474 WeakPolarHBondContact O-CB 3.46Å; L469-A474 PolarHBondContact O-N 3.01Å
470	L	92.4	Very high	92.2	Very high	10 Å²	10	48.7 Å²	48.7	5%	0.052	26%	0.257	C	S	.	.	I	π-helix	trans	-71.2	-32.2	-178.4	-69.3	165.4	0	0	0	113.7	L307 S443 L447 T466 L467 P475	L307-L470 HydrophobicContact CD2-CD2 4.49Å; S443-L470 WeakPolarHBondContact OG-CD1 3.4Å; L447-L470 HydrophobicContact CD2-CD1 4.37Å; L447-L470 HydrophobicContact CG-CD1 4.46Å; T466-L470 HydrophobicContact CG2-CD1 3.73Å; T466-L470 HydrophobicContact CG2-CG 4.39Å; T466-L470 WeakPolarHBondContact O-CB 3.22Å; T466-L470 WeakPolarHBondContact O-CD1 3.38Å; T466-L470 VanDerWaalsContact O-CG 3.24Å; T466-L470 WeakPolarHBondContact O-CG 3.33Å; T466-L470 PolarHBondContact O-N 3.5Å; L467-L470 PolarHBondContact O-N 3.31Å; L470-P475 WeakPolarHBondContact O-CD 3.36Å; L470-P475 WeakPolarHBondContact O-CG 3.04Å
471	V	91.1	Very high	92.6	Very high	0 Å²	0	50.5 Å²	50.5	0%	0	26%	0.264	C	S	.	.	I	π-helix	trans	-88.4	-24	-179.2	166.5	0	0	0	0	112.8	L308 N311 F315 V371 L467	L308-V471 HydrophobicContact CD1-CB 4.44Å; L308-V471 HydrophobicContact CD1-CG1 3.67Å; N311-V471 HydrophobicContact CB-CG2 3.89Å; F315-V471 HydrophobicContact CB-CG2 3.85Å; F315-V471 HydrophobicContact CD1-CG1 4.36Å; F315-V471 HydrophobicContact CD2-CG2 4.37Å; F315-V471 HydrophobicContact CG-CG1 4.36Å; F315-V471 HydrophobicContact CG-CG2 4.11Å; V371-V471 HydrophobicContact CG1-CG1 4.26Å; L467-V471 WeakPolarHBondContact O-CB 2.97Å; L467-V471 WeakPolarHBondContact O-CG2 3.27Å; L467-V471 PolarHBondContact O-N 2.98Å
472	S	91.8	Very high	92.9	Very high	13 Å²	13	42.1 Å²	42.1	9%	0.091	23%	0.228	C	C	.	.	I	π-helix	trans	-124.8	-71.7	-173.4	-169.3	0	0	0	0	113.3	M368 K468 A474 P475 V476	M368-S472 VanDerWaalsContact C-OG 3.26Å; M368-S472 VanDerWaalsContact O-CB 3.29Å; M368-S472 WeakPolarHBondContact O-CB 3.2Å; M368-S472 PolarHBondContact O-OG 2.94Å; K468-S472 VanDerWaalsContact O-CB 3.3Å; K468-S472 WeakPolarHBondContact O-CB 3.28Å; K468-S472 PolarHBondContact O-N 3.35Å; K468-S472 VanDerWaalsContact O-N 3.09Å; S472-A474 PolarHBondContact O-N 2.88Å; S472-P475 WeakPolarHBondContact O-CD 3.48Å; S472-V476 WeakPolarHBondContact O-CB 3.32Å; S472-V476 WeakPolarHBondContact O-CG2 3.33Å; S472-V476 PolarHBondContact O-N 3.44Å
473	A	93.3	Very high	92.9	Very high	51 Å²	51	37 Å²	37	42%	0.421	20%	0.204	S	C	.	.	I	π-helix	trans	-63	-46.1	-168.8	0	0	0	0	0	113.3	L469 V476 V477	L469-A473 HydrophobicContact CG-CB 4.37Å; L469-A473 PolarHBondContact O-N 3.21Å; A473-V476 PolarHBondContact O-N 3.3Å; A473-V477 WeakPolarHBondContact O-CG2 3.38Å; A473-V477 PolarHBondContact O-N 3.06Å; A473-V477 VanDerWaalsContact O-N 3.1Å
474	A	94.1	Very high	93.1	Very high	26 Å²	26	39 Å²	39	22%	0.215	23%	0.225	C	C	.	.	H	α-helix	trans	-65.3	-50.8	180	0	0	0	0	0	112.3	L469 S472 V476 V477 L478	L469-A474 HydrophobicContact CD2-CB 4.11Å; L469-A474 WeakPolarHBondContact O-CB 3.46Å; L469-A474 PolarHBondContact O-N 3.01Å; S472-A474 PolarHBondContact O-N 2.88Å; A474-V476 VanDerWaalsContact C-N 3.32Å; A474-V476 PolarHBondContact O-N 3.1Å; A474-V477 PolarHBondContact O-N 2.9Å; A474-L478 VanDerWaalsContact O-CG 3.28Å; A474-L478 WeakPolarHBondContact O-CG 3.12Å; A474-L478 PolarHBondContact O-N 3.17Å
475	P	94.3	Very high	93.4	Very high	0 Å²	0	38.7 Å²	38.7	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-55.1	-41.4	172.6	-31.2	37.7	0	0	0	114.3	A304 L307 M368 L470 S472 L478 I479	A304-P475 HydrophobicContact CB-CB 3.91Å; A304-P475 WeakPolarHBondContact CB-O 3Å; L307-P475 HydrophobicContact CB-CG 4.15Å; M368-P475 HydrophobicContact CE-CB 3.67Å; M368-P475 HydrophobicContact SD-CB 3.57Å; M368-P475 VanDerWaalsContact SD-CB 3.57Å; L470-P475 WeakPolarHBondContact O-CD 3.36Å; L470-P475 WeakPolarHBondContact O-CG 3.04Å; S472-P475 WeakPolarHBondContact O-CD 3.48Å; P475-L478 PolarHBondContact O-N 3.36Å; P475-I479 WeakPolarHBondContact O-CG1 3.27Å; P475-I479 PolarHBondContact O-N 3.43Å
476	V	95	Very high	93.2	Very high	20 Å²	20	33.5 Å²	33.5	12%	0.121	20%	0.195	C	C	.	.	H	α-helix	trans	-62.3	-46.1	179	169.6	0	0	0	0	111.4	V365 M368 S472 A473 A474 L478 I479 F480	V365-V476 HydrophobicContact CG1-CG1 3.98Å; V365-V476 HydrophobicContact CG1-CG2 4.1Å; V365-V476 HydrophobicContact CG2-CG1 4.47Å; V365-V476 HydrophobicContact CG2-CG2 4.49Å; M368-V476 HydrophobicContact CB-CG2 4Å; M368-V476 HydrophobicContact SD-CG2 3.95Å; S472-V476 WeakPolarHBondContact O-CB 3.32Å; S472-V476 WeakPolarHBondContact O-CG2 3.33Å; S472-V476 PolarHBondContact O-N 3.44Å; A473-V476 PolarHBondContact O-N 3.3Å; A474-V476 VanDerWaalsContact C-N 3.32Å; A474-V476 PolarHBondContact O-N 3.1Å; V476-L478 VanDerWaalsContact C-N 3.34Å; V476-L478 PolarHBondContact O-N 3.02Å; V476-I479 PolarHBondContact O-N 3.41Å; V476-F480 HydrophobicContact CG1-CD2 3.78Å; V476-F480 HydrophobicContact CG1-CE2 3.54Å; V476-F480 WeakPolarHBondContact O-CD2 3.48Å; V476-F480 PolarHBondContact O-N 3.27Å
477	V	95.6	Very high	93.1	Very high	85 Å²	85	40.4 Å²	40.4	52%	0.515	22%	0.219	S	C	.	.	H	α-helix	trans	-61.3	-43.7	176.4	171.9	0	0	0	0	111	A473 A474 I479 F480 I481	A473-V477 WeakPolarHBondContact O-CG2 3.38Å; A473-V477 PolarHBondContact O-N 3.06Å; A473-V477 VanDerWaalsContact O-N 3.1Å; A474-V477 PolarHBondContact O-N 2.9Å; V477-I479 PolarHBondContact O-N 3.32Å; V477-F480 PolarHBondContact O-N 2.95Å; V477-I481 HydrophobicContact CG1-CD1 3.82Å; V477-I481 HydrophobicContact CG1-CG1 4.46Å; V477-I481 WeakPolarHBondContact O-CG1 3.43Å; V477-I481 PolarHBondContact O-N 2.89Å
478	L	95.1	Very high	92.9	Very high	27 Å²	27	43.9 Å²	43.9	14%	0.141	24%	0.24	C	C	.	.	H	α-helix	trans	-63.4	-39.2	178	-68.8	171.9	0	0	0	112.5	F300 L303 A304 L307 A474 P475 V476 I481 G482	F300-L478 HydrophobicContact CD1-CD2 3.87Å; F300-L478 HydrophobicContact CE1-CD2 4.43Å; L303-L478 HydrophobicContact CB-CD1 4.45Å; L303-L478 HydrophobicContact CD2-CD1 3.83Å; L303-L478 HydrophobicContact CD2-CD2 4Å; L303-L478 HydrophobicContact CG-CD1 4.03Å; A304-L478 HydrophobicContact CB-CB 3.89Å; A304-L478 HydrophobicContact CB-CD1 4.46Å; L307-L478 HydrophobicContact CD1-CD1 3.61Å; A474-L478 VanDerWaalsContact O-CG 3.28Å; A474-L478 WeakPolarHBondContact O-CG 3.12Å; A474-L478 PolarHBondContact O-N 3.17Å; P475-L478 PolarHBondContact O-N 3.36Å; V476-L478 VanDerWaalsContact C-N 3.34Å; V476-L478 PolarHBondContact O-N 3.02Å; L478-I481 PolarHBondContact O-N 3.39Å; L478-G482 PolarHBondContact O-N 3.2Å
479	I	94.5	Very high	92.7	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-61.7	-46.2	173.9	-72.5	168	0	0	0	110.5	A304 A364 V365 M368 P475 V476 V477 I481 G482 L483	A304-I479 HydrophobicContact CB-CD1 4.21Å; A304-I479 HydrophobicContact CB-CG1 3.69Å; A364-I479 HydrophobicContact CB-CD1 4.17Å; V365-I479 HydrophobicContact CG2-CG2 4.32Å; M368-I479 HydrophobicContact CE-CD1 3.86Å; M368-I479 HydrophobicContact SD-CD1 4Å; P475-I479 WeakPolarHBondContact O-CG1 3.27Å; P475-I479 PolarHBondContact O-N 3.43Å; V476-I479 PolarHBondContact O-N 3.41Å; V477-I479 PolarHBondContact O-N 3.32Å; I479-I481 PolarHBondContact O-N 3.19Å; I479-G482 PolarHBondContact O-N 3.5Å; I479-L483 HydrophobicContact CG2-CD1 3.83Å; I479-L483 HydrophobicContact CG2-CG 4.18Å; I479-L483 WeakPolarHBondContact O-CB 3.26Å; I479-L483 VanDerWaalsContact O-CG 3.29Å; I479-L483 WeakPolarHBondContact O-CG 3.35Å; I479-L483 PolarHBondContact O-N 2.85Å
480	F	95.5	Very high	92.2	Very high	108 Å²	108	39 Å²	39	47%	0.474	22%	0.221	S	C	.	.	H	α-helix	trans	-63.5	-40.3	178.3	-79.2	-64.8	0	0	0	112.6	L362 V365 V476 V477 L483 G484	L362-F480 HydrophobicContact CD1-CE1 3.76Å; L362-F480 HydrophobicContact CD1-CZ 4.05Å; V365-F480 HydrophobicContact CG1-CE2 4.49Å; V476-F480 HydrophobicContact CG1-CD2 3.78Å; V476-F480 HydrophobicContact CG1-CE2 3.54Å; V476-F480 WeakPolarHBondContact O-CD2 3.48Å; V476-F480 PolarHBondContact O-N 3.27Å; V477-F480 PolarHBondContact O-N 2.95Å; F480-L483 PolarHBondContact O-N 3.4Å; F480-G484 PolarHBondContact O-N 2.81Å
481	I	95.5	Very high	91.8	Very high	74 Å²	74	39 Å²	39	38%	0.379	22%	0.22	S	C	.	.	H	α-helix	trans	-61.8	-48	174.1	-67.1	167	0	0	0	110.3	F300 V477 L478 I479 L483 G484 I485	F300-I481 HydrophobicContact CD1-CG2 4.36Å; F300-I481 HydrophobicContact CD2-CG2 3.92Å; F300-I481 HydrophobicContact CE1-CG2 4.47Å; F300-I481 HydrophobicContact CE2-CG2 4.05Å; F300-I481 HydrophobicContact CG-CG2 4.09Å; F300-I481 HydrophobicContact CZ-CG2 4.32Å; V477-I481 HydrophobicContact CG1-CD1 3.82Å; V477-I481 HydrophobicContact CG1-CG1 4.46Å; V477-I481 WeakPolarHBondContact O-CG1 3.43Å; V477-I481 PolarHBondContact O-N 2.89Å; L478-I481 PolarHBondContact O-N 3.39Å; I479-I481 PolarHBondContact O-N 3.19Å; I481-L483 PolarHBondContact O-N 3.09Å; I481-G484 PolarHBondContact O-N 3.26Å; I481-I485 HydrophobicContact CG2-CD1 4.08Å; I481-I485 WeakPolarHBondContact O-CG1 3.22Å; I481-I485 PolarHBondContact O-N 3.23Å
482	G	93.4	Very high	91.4	Very high	0 Å²	0	42.2 Å²	42.2	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-60.1	-44.7	178.2	0	0	0	0	0	112.8	G297 L478 I479 I485 L486	G297-G482 WeakPolarHBondContact O-CA 3.4Å; L478-G482 PolarHBondContact O-N 3.2Å; I479-G482 PolarHBondContact O-N 3.5Å; G482-I485 PolarHBondContact O-N 2.93Å; G482-L486 WeakPolarHBondContact O-CG 3.25Å; G482-L486 PolarHBondContact O-N 3.15Å
483	L	92.7	Very high	90.8	Very high	10 Å²	10	44.9 Å²	44.9	5%	0.052	25%	0.251	C	S	.	.	H	α-helix	trans	-66.6	-35	176.2	-73.2	-177.7	0	0	0	113.1	Y358 L362 I479 F480 I481 L486 Y487	Y358-L483 HydrophobicContact CD1-CB 4.33Å; Y358-L483 HydrophobicContact CD1-CD1 4.28Å; Y358-L483 HydrophobicContact CD1-CD2 3.7Å; Y358-L483 HydrophobicContact CD1-CG 4.32Å; Y358-L483 HydrophobicContact CE1-CB 3.94Å; Y358-L483 HydrophobicContact CE1-CD2 3.9Å; Y358-L483 HydrophobicContact CE1-CG 4.39Å; Y358-L483 HydrophobicContact CG-CD2 4.38Å; Y358-L483 PolarHBondContact OH-O 3.47Å; L362-L483 HydrophobicContact CB-CD1 4.44Å; L362-L483 HydrophobicContact CD1-CD1 4.22Å; I479-L483 HydrophobicContact CG2-CD1 3.83Å; I479-L483 HydrophobicContact CG2-CG 4.18Å; I479-L483 WeakPolarHBondContact O-CB 3.26Å; I479-L483 VanDerWaalsContact O-CG 3.29Å; I479-L483 WeakPolarHBondContact O-CG 3.35Å; I479-L483 PolarHBondContact O-N 2.85Å; F480-L483 PolarHBondContact O-N 3.4Å; I481-L483 PolarHBondContact O-N 3.09Å; L483-L486 HydrophobicContact CD2-CD1 4.3Å; L483-L486 PolarHBondContact O-N 2.94Å; L483-Y487 PolarHBondContact O-N 3.42Å
484	G	94.1	Very high	90.3	Very high	42 Å²	42	50.1 Å²	50.1	43%	0.433	27%	0.267	S	S	.	.	H	α-helix	trans	-63.6	-41.9	173.1	0	0	0	0	0	112	F480 I481 Y487	F480-G484 PolarHBondContact O-N 2.81Å; I481-G484 PolarHBondContact O-N 3.26Å; G484-Y487 VanDerWaalsContact O-CB 3.29Å; G484-Y487 WeakPolarHBondContact O-CB 3.34Å; G484-Y487 PolarHBondContact O-N 2.85Å
485	I	93.1	Very high	89.8	Confident	43 Å²	43	53.3 Å²	53.3	22%	0.221	27%	0.273	C	S	.	.	H	α-helix	trans	-67.5	-44.3	175	-64.9	165.1	0	0	0	110.6	K293 M296 F300 I481 G482 Y487 T488	K293-I485 WeakPolarHBondContact O-CG2 3.4Å; M296-I485 HydrophobicContact CB-CG2 4.36Å; F300-I485 HydrophobicContact CD2-CD1 3.58Å; F300-I485 HydrophobicContact CE2-CD1 3.59Å; I481-I485 HydrophobicContact CG2-CD1 4.08Å; I481-I485 WeakPolarHBondContact O-CG1 3.22Å; I481-I485 PolarHBondContact O-N 3.23Å; G482-I485 PolarHBondContact O-N 2.93Å; I485-Y487 PolarHBondContact O-N 2.68Å; I485-Y487 VanDerWaalsContact O-N 3.12Å; I485-T488 PolarHBondContact O-N 3.21Å; I485-T488 PolarHBondContact O-OG1 3.05Å
486	L	88.9	Confident	89.1	Confident	6 Å²	6	55.6 Å²	55.6	3%	0.031	28%	0.282	C	S	.	.	H	α-helix	trans	-61.1	-19	175.8	-74.5	173.1	0	0	0	113.1	L294 Y358 G482 L483 Y489	L294-L486 HydrophobicContact CD1-CD2 4.03Å; Y358-L486 VanDerWaalsContact OH-C 3.29Å; G482-L486 WeakPolarHBondContact O-CG 3.25Å; G482-L486 PolarHBondContact O-N 3.15Å; L483-L486 HydrophobicContact CD2-CD1 4.3Å; L483-L486 PolarHBondContact O-N 2.94Å; L486-Y489 WeakPolarHBondContact O-CB 3.38Å; L486-Y489 PolarHBondContact O-N 3.47Å
487	Y	88.9	Confident	88.5	Confident	177 Å²	177	59.6 Å²	59.6	69%	0.694	30%	0.299	S	S	*	.	H	α-helix	trans	-66.8	-42.6	174.8	-177.3	-103.7	0	0	0	111.2	K354 Y358 L483 G484 I485 Y489	K354-Y487 PolarHBondContact NZ-O 3Å; K354-Y487 VanDerWaalsContact NZ-O 3.1Å; Y358-Y487 WeakPolarHBondContact OH-CA 3.01Å; Y358-Y487 WeakPolarHBondContact OH-CB 3.32Å; Y358-Y487 PolarHBondContact OH-N 3.36Å; L483-Y487 PolarHBondContact O-N 3.42Å; G484-Y487 VanDerWaalsContact O-CB 3.29Å; G484-Y487 WeakPolarHBondContact O-CB 3.34Å; G484-Y487 PolarHBondContact O-N 2.85Å; I485-Y487 PolarHBondContact O-N 2.68Å; I485-Y487 VanDerWaalsContact O-N 3.12Å; Y487-Y489 PolarHBondContact O-N 2.97Å
488	T	87.9	Confident	87.9	Confident	72 Å²	72	57 Å²	57	44%	0.442	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74	0.3	178.6	74.7	0	0	0	0	113.9	K293 I485	K293-T488 PolarHBondContact NZ-O 3.28Å; K293-T488 VanDerWaalsContact NZ-O 3.07Å; I485-T488 PolarHBondContact O-N 3.21Å; I485-T488 PolarHBondContact O-OG1 3.05Å
489	Y	87.1	Confident	87.4	Confident	6 Å²	6	56.5 Å²	56.5	2%	0.024	29%	0.287	C	S	.	.			trans	-69.4	121.5	177.3	-177.7	-113.2	0	0	0	110.6	L294 K354 M402 V406 L486 Y487 I491	L294-Y489 HydrophobicContact CB-CD2 4.21Å; L294-Y489 HydrophobicContact CB-CE2 3.87Å; L294-Y489 HydrophobicContact CD1-CD2 4.14Å; L294-Y489 HydrophobicContact CD1-CE1 4.32Å; L294-Y489 HydrophobicContact CD1-CE2 3.79Å; L294-Y489 HydrophobicContact CG-CE2 4.31Å; K354-Y489 PolarHBondContact NZ-O 2.86Å; M402-Y489 HydrophobicContact CE-CD1 4.06Å; M402-Y489 HydrophobicContact CE-CE1 3.73Å; V406-Y489 HydrophobicContact CG2-CE2 3.96Å; V406-Y489 WeakPolarHBondContact CG2-OH 3.25Å; L486-Y489 WeakPolarHBondContact O-CB 3.38Å; L486-Y489 PolarHBondContact O-N 3.47Å; Y487-Y489 PolarHBondContact O-N 2.97Å; Y489-I491 HydrophobicContact CD1-CB 4.38Å; Y489-I491 HydrophobicContact CE1-CB 3.61Å; Y489-I491 HydrophobicContact CE1-CG1 4.48Å; Y489-I491 HydrophobicContact CE1-CG2 4.44Å; Y489-I491 WeakPolarHBondContact CE1-O 3.31Å; Y489-I491 HydrophobicContact CE2-CB 4.42Å; Y489-I491 HydrophobicContact CE2-CD1 4.04Å; Y489-I491 HydrophobicContact CE2-CG1 4.45Å; Y489-I491 VanDerWaalsContact OH-CD1 3.23Å; Y489-I491 WeakPolarHBondContact OH-CD1 3.47Å
490	P	82.4	Confident	86.8	Confident	50 Å²	50	64.2 Å²	64.2	33%	0.325	32%	0.316	S	S	.	.			trans	-85.4	-13.7	-166.4	32.4	-35.5	0	0	0	114.7	P290 T492	P290-P490 HydrophobicContact CB-CG 3.98Å; P290-P490 HydrophobicContact CG-CG 3.91Å; P490-T492 PolarHBondContact O-N 3.28Å
491	I	82.9	Confident	86.3	Confident	9 Å²	9	65.3 Å²	65.3	5%	0.046	32%	0.321	C	S	.	.			trans	-85.3	106.2	-175.1	-61.3	161.9	0	0	0	109.2	P290 V406 D409 Y489	P290-I491 HydrophobicContact CB-CD1 4.02Å; V406-I491 HydrophobicContact CB-CD1 4.5Å; V406-I491 HydrophobicContact CG2-CD1 3.97Å; D409-I491 HydrophobicContact CB-CD1 3.89Å; Y489-I491 HydrophobicContact CD1-CB 4.38Å; Y489-I491 HydrophobicContact CE1-CB 3.61Å; Y489-I491 HydrophobicContact CE1-CG1 4.48Å; Y489-I491 HydrophobicContact CE1-CG2 4.44Å; Y489-I491 WeakPolarHBondContact CE1-O 3.31Å; Y489-I491 HydrophobicContact CE2-CB 4.42Å; Y489-I491 HydrophobicContact CE2-CD1 4.04Å; Y489-I491 HydrophobicContact CE2-CG1 4.45Å; Y489-I491 VanDerWaalsContact OH-CD1 3.23Å; Y489-I491 WeakPolarHBondContact OH-CD1 3.47Å
492	T	83.3	Confident	85.8	Confident	67 Å²	67	65.2 Å²	65.2	41%	0.411	32%	0.32	S	S	.	.			trans	-89.1	168.9	173.9	57.3	0	0	0	0	111.5	P490 E494 R495 R496	P490-T492 PolarHBondContact O-N 3.28Å; T492-E494 PolarHBondContact O-N 3.46Å; T492-R495 PolarHBondContact O-N 2.82Å; T492-R495 PolarHBondContact OG1-N 3.42Å; T492-R496 PolarHBondContact O-N 3.31Å
493	E	79.7	Confident	85.3	Confident	70 Å²	70	66.2 Å²	66.2	33%	0.327	33%	0.326	S	S	.	.	H	α-helix	trans	-55.4	-41.2	174.5	-172.8	65.6	-139.1	0	0	111.9	R496 Q497	E493-R496 PolarHBondContact O-N 2.03Å; E493-R496 IonicContact OE1-CZ 2.67Å; E493-R496 IonicContact OE1-NE 2.65Å; E493-R496 IonicContact OE1-NH1 3.36Å; E493-R496 PolarHBondContact OE1-NH1 3.09Å; E493-R496 IonicContact OE1-NH2 2.7Å; E493-R496 PolarHBondContact OE1-NH2 2.9Å; E493-R496 IonicContact OE2-CZ 2.83Å; E493-R496 IonicContact OE2-NH1 3.74Å; E493-R496 PolarHBondContact OE2-NH1 3.3Å; E493-R496 IonicContact OE2-NH2 2.69Å; E493-R496 PolarHBondContact OE2-NH2 3.4Å; E493-Q497 WeakPolarHBondContact O-CG 3.49Å; E493-Q497 PolarHBondContact O-N 3.32Å
494	E	81.9	Confident	84.7	Confident	160 Å²	160	71 Å²	71	75%	0.748	35%	0.348	S	S	*	.	H	α-helix	trans	-63	-47.7	177.9	-65	176.6	178.8	0	0	112.1	T492 R496 Q497 G498	T492-E494 PolarHBondContact O-N 3.46Å; E494-R496 VanDerWaalsContact C-N 3.28Å; E494-R496 PolarHBondContact O-N 3.41Å; E494-Q497 PolarHBondContact O-N 3.17Å; E494-G498 PolarHBondContact O-N 3.27Å
495	R	83.4	Confident	84.2	Confident	94 Å²	94	75.4 Å²	75.4	36%	0.355	36%	0.357	S	S	.	.	H	α-helix	trans	-62	-38.3	178	-174.3	169.3	173.9	154.8	0.2	111.5	D409 Q413 T492 G498 N499	D409-R495 IonicContact OD1-CZ 3.35Å; D409-R495 IonicContact OD1-NE 3.84Å; D409-R495 PolarHBondContact OD1-NE 3.48Å; D409-R495 IonicContact OD1-NH2 2.95Å; D409-R495 PolarHBondContact OD1-NH2 3.17Å; D409-R495 IonicContact OD2-CZ 3.81Å; D409-R495 IonicContact OD2-NE 3.77Å; D409-R495 IonicContact OD2-NH2 3.19Å; D409-R495 PolarHBondContact OD2-NH2 2.87Å; Q413-R495 VanDerWaalsContact NE2-NH2 3.14Å; T492-R495 PolarHBondContact O-N 2.82Å; T492-R495 PolarHBondContact OG1-N 3.42Å; R495-G498 PolarHBondContact O-N 3.49Å; R495-N499 VanDerWaalsContact O-CG 3.27Å; R495-N499 PolarHBondContact O-N 3.43Å; R495-N499 PolarHBondContact O-OD1 3.33Å
496	R	80.8	Confident	83.5	Confident	47 Å²	47	75.7 Å²	75.7	18%	0.177	36%	0.359	C	S	.	.	H	α-helix	trans	-61.9	-47.3	174.4	-174.7	178.1	77	-118	-151.7	112	D405 T492 E493 E494 G498 N499 R500	D405-R496 WeakPolarHBondContact OD1-CD 3.47Å; D405-R496 WeakPolarHBondContact OD2-CD 3.5Å; T492-R496 PolarHBondContact O-N 3.31Å; E493-R496 PolarHBondContact O-N 2.03Å; E493-R496 IonicContact OE1-CZ 2.67Å; E493-R496 IonicContact OE1-NE 2.65Å; E493-R496 IonicContact OE1-NH1 3.36Å; E493-R496 PolarHBondContact OE1-NH1 3.09Å; E493-R496 IonicContact OE1-NH2 2.7Å; E493-R496 PolarHBondContact OE1-NH2 2.9Å; E493-R496 IonicContact OE2-CZ 2.83Å; E493-R496 IonicContact OE2-NH1 3.74Å; E493-R496 PolarHBondContact OE2-NH1 3.3Å; E493-R496 IonicContact OE2-NH2 2.69Å; E493-R496 PolarHBondContact OE2-NH2 3.4Å; E494-R496 VanDerWaalsContact C-N 3.28Å; E494-R496 PolarHBondContact O-N 3.41Å; R496-G498 VanDerWaalsContact C-N 3.27Å; R496-G498 PolarHBondContact O-N 2.87Å; R496-N499 PolarHBondContact O-N 2.72Å; R496-R500 WeakPolarHBondContact O-CB 3.27Å; R496-R500 PolarHBondContact O-N 3.32Å
497	Q	80.8	Confident	82.9	Confident	105 Å²	105	78.4 Å²	78.4	49%	0.491	38%	0.378	S	S	.	.	H	α-helix	trans	-63.1	-36.7	178.3	-70	-179.3	9.9	0	0	111.7	E493 E494 K501	E493-Q497 WeakPolarHBondContact O-CG 3.49Å; E493-Q497 PolarHBondContact O-N 3.32Å; E494-Q497 PolarHBondContact O-N 3.17Å; Q497-K501 WeakPolarHBondContact O-CG 3.41Å; Q497-K501 PolarHBondContact O-N 3.49Å
498	G	83.8	Confident	82.3	Confident	31 Å²	31	73.8 Å²	73.8	32%	0.32	37%	0.371	S	S	.	.	H	α-helix	trans	-60.9	-53.7	172.2	0	0	0	0	0	112.4	E494 R495 R496 R500 K501 I502	E494-G498 PolarHBondContact O-N 3.27Å; R495-G498 PolarHBondContact O-N 3.49Å; R496-G498 VanDerWaalsContact C-N 3.27Å; R496-G498 PolarHBondContact O-N 2.87Å; G498-R500 VanDerWaalsContact C-N 3.29Å; G498-R500 PolarHBondContact O-N 3.05Å; G498-K501 PolarHBondContact O-N 3.24Å; G498-K501 VanDerWaalsContact O-N 3.14Å; G498-I502 WeakPolarHBondContact O-CG1 3.46Å; G498-I502 PolarHBondContact O-N 2.88Å; G498-I502 VanDerWaalsContact O-N 3.11Å
499	N	85.4	Confident	81.6	Confident	15 Å²	15	77.4 Å²	77.4	8%	0.08	38%	0.377	C	S	.	.	H	α-helix	trans	-59.2	-40.2	179.8	-69	-7.2	0	0	0	112.2	D409 V412 R495 R496 K501 I502 L503	D409-N499 VanDerWaalsContact CA-ND2 3.29Å; D409-N499 WeakPolarHBondContact CA-ND2 3.49Å; D409-N499 VanDerWaalsContact CB-ND2 3.25Å; D409-N499 WeakPolarHBondContact CB-ND2 3.45Å; D409-N499 PolarHBondContact OD1-ND2 3.21Å; V412-N499 HydrophobicContact CG2-CB 4.04Å; R495-N499 VanDerWaalsContact O-CG 3.27Å; R495-N499 PolarHBondContact O-N 3.43Å; R495-N499 PolarHBondContact O-OD1 3.33Å; R496-N499 PolarHBondContact O-N 2.72Å; N499-K501 VanDerWaalsContact C-N 3.33Å; N499-K501 PolarHBondContact O-N 2.91Å; N499-I502 PolarHBondContact O-N 3.09Å; N499-L503 WeakPolarHBondContact O-CG 3.43Å; N499-L503 PolarHBondContact O-N 3.03Å
500	R	81.7	Confident	80.9	Confident	162 Å²	162	81.9 Å²	81.9	61%	0.611	40%	0.401	S	S	*	.	H	α-helix	trans	-62.9	-38.7	178	-168.2	175.7	-174	-178.2	3.9	112.6	R496 G498 Q504	R496-R500 WeakPolarHBondContact O-CB 3.27Å; R496-R500 PolarHBondContact O-N 3.32Å; G498-R500 VanDerWaalsContact C-N 3.29Å; G498-R500 PolarHBondContact O-N 3.05Å; R500-Q504 WeakPolarHBondContact O-CB 3.48Å; R500-Q504 VanDerWaalsContact O-CG 3.29Å; R500-Q504 WeakPolarHBondContact O-CG 3.2Å; R500-Q504 PolarHBondContact O-N 2.99Å
501	K	85.2	Confident	80.3	Confident	131 Å²	131	85.9 Å²	85.9	57%	0.57	42%	0.415	S	S	*	.	H	α-helix	trans	-65.7	-45.2	175.3	-72	175.8	-179.2	-178.1	0	111.3	Q497 G498 N499 L503 Q504 E505	Q497-K501 WeakPolarHBondContact O-CG 3.41Å; Q497-K501 PolarHBondContact O-N 3.49Å; G498-K501 PolarHBondContact O-N 3.24Å; G498-K501 VanDerWaalsContact O-N 3.14Å; N499-K501 VanDerWaalsContact C-N 3.33Å; N499-K501 PolarHBondContact O-N 2.91Å; K501-L503 VanDerWaalsContact C-N 3.34Å; K501-L503 PolarHBondContact O-N 3.09Å; K501-Q504 PolarHBondContact O-N 3.19Å; K501-E505 WeakPolarHBondContact O-CG 3.27Å; K501-E505 PolarHBondContact O-N 3.01Å
502	I	85.5	Confident	79.6	Confident	72 Å²	72	88.2 Å²	88.2	37%	0.369	44%	0.436	S	S	.	.	H	α-helix	trans	-60.9	-44.5	178.4	-63.2	165.5	0	0	0	110.7	V412 G498 N499 E505 L506	V412-I502 HydrophobicContact CG1-CD1 4.02Å; V412-I502 HydrophobicContact CG1-CG2 4.09Å; V412-I502 HydrophobicContact CG2-CB 4.35Å; V412-I502 HydrophobicContact CG2-CG2 4.23Å; G498-I502 WeakPolarHBondContact O-CG1 3.46Å; G498-I502 PolarHBondContact O-N 2.88Å; G498-I502 VanDerWaalsContact O-N 3.11Å; N499-I502 PolarHBondContact O-N 3.09Å; I502-E505 PolarHBondContact O-N 2.96Å; I502-L506 HydrophobicContact CG2-CD1 4.17Å; I502-L506 WeakPolarHBondContact O-CG 3.36Å; I502-L506 PolarHBondContact O-N 2.68Å
503	L	81	Confident	78.8	Confident	22 Å²	22	89.2 Å²	89.2	12%	0.115	44%	0.438	C	S	.	.	H	α-helix	trans	-64.3	-40.3	177	-77.5	160	0	0	0	112.2	D408 Q411 V412 N499 K501 L506 S507	D408-L503 HydrophobicContact CB-CD1 3.6Å; Q411-L503 HydrophobicContact CB-CD2 4.27Å; Q411-L503 HydrophobicContact CG-CD2 3.87Å; V412-L503 HydrophobicContact CG2-CD1 4.01Å; V412-L503 HydrophobicContact CG2-CD2 4.31Å; V412-L503 HydrophobicContact CG2-CG 3.77Å; N499-L503 WeakPolarHBondContact O-CG 3.43Å; N499-L503 PolarHBondContact O-N 3.03Å; K501-L503 VanDerWaalsContact C-N 3.34Å; K501-L503 PolarHBondContact O-N 3.09Å; L503-L506 PolarHBondContact O-N 2.69Å; L503-S507 PolarHBondContact O-N 3.39Å; L503-S507 PolarHBondContact O-OG 2.87Å; L503-S507 VanDerWaalsContact O-OG 3.14Å
504	Q	81.7	Confident	78.2	Confident	109 Å²	109	89.1 Å²	89.1	51%	0.509	45%	0.446	S	S	.	.	H	α-helix	trans	-62.4	-42.1	174.3	-77.6	178.8	-32.6	0	0	112	R500 K501 S507 C508	R500-Q504 WeakPolarHBondContact O-CB 3.48Å; R500-Q504 VanDerWaalsContact O-CG 3.29Å; R500-Q504 WeakPolarHBondContact O-CG 3.2Å; R500-Q504 PolarHBondContact O-N 2.99Å; K501-Q504 PolarHBondContact O-N 3.19Å; Q504-S507 PolarHBondContact O-N 3.44Å; Q504-C508 WeakPolarHBondContact O-CB 3.45Å; Q504-C508 PolarHBondContact O-N 3.21Å; Q504-C508 PolarHBondContact O-SG 3.37Å; Q504-C508 VanDerWaalsContact O-SG 3.32Å
505	E	83.4	Confident	77.3	Confident	136 Å²	136	84 Å²	84	64%	0.636	43%	0.431	S	S	*	.	H	α-helix	trans	-63.1	-40.8	175.7	-73.4	171.6	-169.3	0	0	112	K501 I502 C508 R509	K501-E505 WeakPolarHBondContact O-CG 3.27Å; K501-E505 PolarHBondContact O-N 3.01Å; I502-E505 PolarHBondContact O-N 2.96Å; E505-C508 PolarHBondContact O-N 3.37Å; E505-R509 PolarHBondContact O-N 3.32Å
506	L	78.6	Confident	76.2	Confident	48 Å²	48	82.1 Å²	82.1	25%	0.251	43%	0.432	S	S	.	.	H	α-helix	trans	-63.6	-46.5	174.9	-71.1	170.1	0	0	0	111.6	I502 L503 C508 R509 D510	I502-L506 HydrophobicContact CG2-CD1 4.17Å; I502-L506 WeakPolarHBondContact O-CG 3.36Å; I502-L506 PolarHBondContact O-N 2.68Å; L503-L506 PolarHBondContact O-N 2.69Å; L506-C508 PolarHBondContact O-N 2.9Å; L506-R509 PolarHBondContact O-N 2.88Å; L506-D510 PolarHBondContact O-N 3.33Å
507	S	74.9	Confident	74.9	Confident	63 Å²	63	85 Å²	85	44%	0.441	45%	0.451	S	S	.	.	H	α-helix	trans	-62.4	-41.4	177	-61.1	0	0	0	0	112.6	L503 Q504 R509 D510 E511	L503-S507 PolarHBondContact O-N 3.39Å; L503-S507 PolarHBondContact O-OG 2.87Å; L503-S507 VanDerWaalsContact O-OG 3.14Å; Q504-S507 PolarHBondContact O-N 3.44Å; S507-R509 VanDerWaalsContact C-N 3.29Å; S507-R509 PolarHBondContact O-N 2.85Å; S507-D510 PolarHBondContact O-N 3.02Å; S507-E511 WeakPolarHBondContact O-CB 3.25Å; S507-E511 WeakPolarHBondContact O-CG 3.11Å; S507-E511 PolarHBondContact O-N 3.24Å
508	C	76.8	Confident	73.8	Confident	80 Å²	80	83.4 Å²	83.4	54%	0.541	45%	0.452	S	S	.	.	H	α-helix	trans	-64.5	-33.6	175.7	-72.1	0	0	0	0	112.5	Q504 E505 L506 A512	Q504-C508 WeakPolarHBondContact O-CB 3.45Å; Q504-C508 PolarHBondContact O-N 3.21Å; Q504-C508 PolarHBondContact O-SG 3.37Å; Q504-C508 VanDerWaalsContact O-SG 3.32Å; E505-C508 PolarHBondContact O-N 3.37Å; L506-C508 PolarHBondContact O-N 2.9Å; C508-A512 WeakPolarHBondContact O-CB 3.49Å; C508-A512 PolarHBondContact O-N 3.35Å
509	R	73.7	Confident	72.4	Confident	149 Å²	149	84.8 Å²	84.8	56%	0.562	46%	0.456	S	S	*	.	H	α-helix	trans	-69.3	-45.5	175.3	-168.8	172.4	68.7	-175.4	2.4	111.5	E505 L506 S507 E511 A512 D513	E505-R509 PolarHBondContact O-N 3.32Å; L506-R509 PolarHBondContact O-N 2.88Å; S507-R509 VanDerWaalsContact C-N 3.29Å; S507-R509 PolarHBondContact O-N 2.85Å; R509-E511 VanDerWaalsContact C-N 3.32Å; R509-E511 PolarHBondContact O-N 3.46Å; R509-A512 PolarHBondContact O-N 2.86Å; R509-D513 WeakPolarHBondContact O-CB 3Å; R509-D513 VanDerWaalsContact O-CG 3.27Å; R509-D513 PolarHBondContact O-N 3.35Å
510	D	71.6	Confident	70.7	Confident	100 Å²	100	90.5 Å²	90.5	54%	0.535	48%	0.482	S	S	.	.	H	α-helix	trans	-63.1	-38.5	177.3	-66.3	-14.1	0	0	0	111.6	L506 S507 D513 S514	L506-D510 PolarHBondContact O-N 3.33Å; S507-D510 PolarHBondContact O-N 3.02Å; D510-D513 PolarHBondContact O-N 3.38Å; D510-S514 WeakPolarHBondContact O-CB 3.32Å; D510-S514 PolarHBondContact O-N 2.8Å; D510-S514 PolarHBondContact O-OG 3.37Å
511	E	71.3	Confident	69.2	Low	133 Å²	133	87.8 Å²	87.8	62%	0.621	48%	0.484	S	S	*	.	H	α-helix	trans	-63.9	-43.4	173.4	-77.4	-179.1	-178.9	0	0	111.8	S507 R509 S514 A515	S507-E511 WeakPolarHBondContact O-CB 3.25Å; S507-E511 WeakPolarHBondContact O-CG 3.11Å; S507-E511 PolarHBondContact O-N 3.24Å; R509-E511 VanDerWaalsContact C-N 3.32Å; R509-E511 PolarHBondContact O-N 3.46Å; E511-S514 PolarHBondContact O-N 2.88Å; E511-S514 PolarHBondContact O-OG 3.43Å; E511-A515 WeakPolarHBondContact O-CB 3.31Å; E511-A515 PolarHBondContact O-N 3.4Å
512	A	67.8	Low	67.4	Low	58 Å²	58	87.1 Å²	87.1	48%	0.479	49%	0.491	S	S	.	.	H	α-helix	trans	-63.2	-43.7	176.4	0	0	0	0	0	112.1	C508 R509 A515 S516	C508-A512 WeakPolarHBondContact O-CB 3.49Å; C508-A512 PolarHBondContact O-N 3.35Å; R509-A512 PolarHBondContact O-N 2.86Å; A512-A515 PolarHBondContact O-N 2.91Å; A512-S516 PolarHBondContact O-N 3.21Å; A512-S516 PolarHBondContact O-OG 3.32Å
513	D	66.8	Low	65.5	Low	88 Å²	88	92.1 Å²	92.1	47%	0.471	51%	0.512	S	S	.	.	H	α-helix	trans	-64.8	-40.1	178.3	-68.5	-16.3	0	0	0	111.1	R509 D510 S516 D517	R509-D513 WeakPolarHBondContact O-CB 3Å; R509-D513 VanDerWaalsContact O-CG 3.27Å; R509-D513 PolarHBondContact O-N 3.35Å; D510-D513 PolarHBondContact O-N 3.38Å; D513-S516 WeakPolarHBondContact CA-OG 3.5Å; D513-S516 PolarHBondContact O-N 3.41Å; D513-S516 PolarHBondContact O-OG 2.92Å; D513-D517 PolarHBondContact O-N 3.38Å
514	S	66.1	Low	63.5	Low	68 Å²	68	99.3 Å²	99.3	48%	0.476	56%	0.558	S	S	.	*	H	α-helix	trans	-69.5	-31.8	175.7	73.1	0	0	0	0	113.6	D510 E511 S518	D510-S514 WeakPolarHBondContact O-CB 3.32Å; D510-S514 PolarHBondContact O-N 2.8Å; D510-S514 PolarHBondContact O-OG 3.37Å; E511-S514 PolarHBondContact O-N 2.88Å; E511-S514 PolarHBondContact O-OG 3.43Å; S514-S518 WeakPolarHBondContact O-CB 2.97Å; S514-S518 PolarHBondContact O-N 3.38Å; S514-S518 VanDerWaalsContact O-N 3.08Å; S514-S518 PolarHBondContact O-OG 3.47Å
515	A	64.1	Low	62.6	Low	53 Å²	53	98.8 Å²	98.8	44%	0.438	56%	0.56	S	S	.	*	H	α-helix	trans	-70.6	-37.4	174.5	0	0	0	0	0	111.4	E511 A512 S518 S519	E511-A515 WeakPolarHBondContact O-CB 3.31Å; E511-A515 PolarHBondContact O-N 3.4Å; A512-A515 PolarHBondContact O-N 2.91Å; A515-S518 WeakPolarHBondContact CA-OG 3.27Å; A515-S518 PolarHBondContact O-OG 2.82Å; A515-S518 VanDerWaalsContact O-OG 3.09Å; A515-S519 PolarHBondContact O-N 3.46Å; A515-S519 VanDerWaalsContact O-N 3.16Å; A515-S519 PolarHBondContact O-OG 2.99Å
516	S	58.4	Low	61.5	Low	55 Å²	55	96.8 Å²	96.8	39%	0.385	56%	0.556	S	S	.	*	H	α-helix	trans	-65.6	-45.9	172.2	42.8	0	0	0	0	112.6	A512 D513 S518 S519 E520	A512-S516 PolarHBondContact O-N 3.21Å; A512-S516 PolarHBondContact O-OG 3.32Å; D513-S516 WeakPolarHBondContact CA-OG 3.5Å; D513-S516 PolarHBondContact O-N 3.41Å; D513-S516 PolarHBondContact O-OG 2.92Å; S516-S518 VanDerWaalsContact C-N 3.32Å; S516-S518 PolarHBondContact O-N 3.46Å; S516-S519 WeakPolarHBondContact CA-OG 3.3Å; S516-S519 PolarHBondContact O-N 3.44Å; S516-S519 PolarHBondContact O-OG 3.05Å; S516-E520 PolarHBondContact O-N 2.87Å
517	D	55	Low	60.6	Low	107 Å²	107	99.6 Å²	99.6	57%	0.572	57%	0.573	S	S	*	*	H	α-helix	trans	-61.7	-39	178.6	-96.1	-2.8	0	0	0	112.1	D513 E520 V521	D513-D517 PolarHBondContact O-N 3.38Å; D517-E520 PolarHBondContact O-N 2.86Å; D517-V521 VanDerWaalsContact O-CG2 3.26Å; D517-V521 WeakPolarHBondContact O-CG2 3.38Å; D517-V521 PolarHBondContact O-N 3.36Å
518	S	56.7	Low	59.7	Low	72 Å²	72	101.7 Å²	101.7	50%	0.503	58%	0.581	S	S	.	*	H	α-helix	trans	-72.3	-28.4	178	51.2	0	0	0	0	113.5	S514 A515 S516 T522	S514-S518 WeakPolarHBondContact O-CB 2.97Å; S514-S518 PolarHBondContact O-N 3.38Å; S514-S518 VanDerWaalsContact O-N 3.08Å; S514-S518 PolarHBondContact O-OG 3.47Å; A515-S518 WeakPolarHBondContact CA-OG 3.27Å; A515-S518 PolarHBondContact O-OG 2.82Å; A515-S518 VanDerWaalsContact O-OG 3.09Å; S516-S518 VanDerWaalsContact C-N 3.32Å; S516-S518 PolarHBondContact O-N 3.46Å; S518-T522 PolarHBondContact O-N 3.04Å; S518-T522 PolarHBondContact O-OG1 3.35Å
519	S	54.1	Low	58.7	Low	60 Å²	60	103.1 Å²	103.1	42%	0.42	58%	0.583	S	S	.	*	H	α-helix	trans	-72.8	-37.7	172.1	58.4	0	0	0	0	113.1	A515 S516 V521 T522 E523	A515-S519 PolarHBondContact O-N 3.46Å; A515-S519 VanDerWaalsContact O-N 3.16Å; A515-S519 PolarHBondContact O-OG 2.99Å; S516-S519 WeakPolarHBondContact CA-OG 3.3Å; S516-S519 PolarHBondContact O-N 3.44Å; S516-S519 PolarHBondContact O-OG 3.05Å; S519-V521 PolarHBondContact O-N 3.49Å; S519-T522 PolarHBondContact O-N 2.91Å; S519-T522 PolarHBondContact O-OG1 2.89Å; S519-T522 VanDerWaalsContact O-OG1 3.11Å; S519-E523 PolarHBondContact O-N 3.5Å
520	E	50.8	Low	57.7	Low	134 Å²	134	100 Å²	100	63%	0.626	59%	0.585	S	S	*	*	H	α-helix	trans	-68	-35.3	176.5	-75.2	-171.6	165.2	0	0	112.4	S516 D517 T522 E523	S516-E520 PolarHBondContact O-N 2.87Å; D517-E520 PolarHBondContact O-N 2.86Å; E520-T522 VanDerWaalsContact C-N 3.27Å; E520-T522 PolarHBondContact O-N 3.5Å; E520-E523 PolarHBondContact O-N 3.14Å
521	V	49.7	Very low	56.7	Low	106 Å²	106	100 Å²	100	64%	0.642	59%	0.588	S	S	*	*	H	α-helix	trans	-72.7	-18.1	178.2	176.3	0	0	0	0	112.9	D517 S519	D517-V521 VanDerWaalsContact O-CG2 3.26Å; D517-V521 WeakPolarHBondContact O-CG2 3.38Å; D517-V521 PolarHBondContact O-N 3.36Å; S519-V521 PolarHBondContact O-N 3.49Å
522	T	47.5	Very low	55.6	Low	116 Å²	116	97.5 Å²	97.5	71%	0.712	59%	0.586	S	S	*	*	H	α-helix	trans	-92.1	-9.8	176.9	34.1	0	0	0	0	113.9	S518 S519 E520	S518-T522 PolarHBondContact O-N 3.04Å; S518-T522 PolarHBondContact O-OG1 3.35Å; S519-T522 PolarHBondContact O-N 2.91Å; S519-T522 PolarHBondContact O-OG1 2.89Å; S519-T522 VanDerWaalsContact O-OG1 3.11Å; E520-T522 VanDerWaalsContact C-N 3.27Å; E520-T522 PolarHBondContact O-N 3.5Å
523	E	45.8	Very low	54.6	Low	177 Å²	177	100.8 Å²	100.8	83%	0.827	59%	0.594	S	S	*	*			trans	-98.6	-0.9	177.1	-72.6	-167.7	157.8	0	0	114.5	S519 E520	S519-E523 PolarHBondContact O-N 3.5Å; E520-E523 PolarHBondContact O-N 3.14Å
524	T	39.6	Very low	53.4	Low	173 Å²	173	101.9 Å²	101.9	100%	1.061	61%	0.606	S	S	*	*			trans	-106	0	170.3	60.8	0	0	0	0	111.8

Retrieved 524 of 524 residues in 241.6 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).