A0A087YA67_POEFO Loading...

Retinoid isomerohydrolase

AlphaFold DB , UniProt , Accession A0A087YA67, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 532 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M33.1Very low77.8Confident246 Ų24690.3 Ų90.3100%1.21250%0.504SS*.  097.50-130.7-179.3-89.400105.8S3M1-S3 PolarHBondContact O-N 2.74Å
2V40.1Very low79.4Confident138 Ų13882.8 Ų82.884%0.83646%0.462SS*.PPolyproline II helixtrans-71.2119.8174.5-177.40000105.7R4V2-R4 PolarHBondContact O-N 2.88Å; V2-R4 VanDerWaalsContact O-N 3.13Å
3S51.3Low80.7Confident107 Ų10780.8 Ų80.875%0.74845%0.445SS*.PPolyproline II helixtrans-56119.2175.4530000108.2M1 F5M1-S3 PolarHBondContact O-N 2.74Å; S3-F5 PolarHBondContact O-N 2.65Å
4R75.6Confident81.9Confident158 Ų15881 Ų8160%0.59644%0.44SS*.PPolyproline II helixtrans-65130.2174.9-68.8-176.9-178.9-173.1-0107.6V2V2-R4 PolarHBondContact O-N 2.88Å; V2-R4 VanDerWaalsContact O-N 3.13Å
5F87.6Confident82.9Confident57 Ų5775.9 Ų75.925%0.2541%0.412CS..PPolyproline II helixtrans-71129.1173.6-152.6-95.6000107.8S3 H7 N441 Q462 P464S3-F5 PolarHBondContact O-N 2.65Å; F5-H7 AromaticContact CD1-CE1 3.6Å; F5-H7 AromaticContact CD1-NE2 3.76Å; F5-H7 AromaticContact CE1-CE1 3.65Å; F5-N441 PolarHBondContact O-ND2 2.97Å; F5-Q462 HydrophobicContact CD1-CG 4.47Å; F5-Q462 VanDerWaalsContact CD1-NE2 3.31Å; F5-Q462 HydrophobicContact CD2-CG 4.21Å; F5-Q462 HydrophobicContact CE1-CG 4.12Å; F5-Q462 HydrophobicContact CE2-CG 3.84Å; F5-Q462 HydrophobicContact CG-CG 4.5Å; F5-Q462 HydrophobicContact CZ-CG 3.77Å; F5-P464 HydrophobicContact CZ-CB 4.33Å; F5-P464 HydrophobicContact CZ-CG 4.19Å
6E94.1Very high83.9Confident75 Ų7571.4 Ų71.435%0.3539%0.387SS..  trans-120.5149.7-173.3-57.8-76153.500109.3P8 W351 K355E6-P8 VanDerWaalsContact O-CD 3.32Å; E6-P8 WeakPolarHBondContact O-CD 3.45Å; E6-W351 PolarHBondContact OE2-NE1 3.19Å; E6-K355 IonicContact OE1-NZ 3.65Å; E6-K355 IonicContact OE2-NZ 2.59Å; E6-K355 PolarHBondContact OE2-NZ 3.36Å
7H95.4Very high84.7Confident0 Ų072 Ų720%039%0.387CS..  trans-120.955.9179.5-60.8-75.4000112F5 A9 G10 Y12 W351 D446 E465 Y467F5-H7 AromaticContact CD1-CE1 3.6Å; F5-H7 AromaticContact CD1-NE2 3.76Å; F5-H7 AromaticContact CE1-CE1 3.65Å; H7-A9 PolarHBondContact O-N 3.47Å; H7-A9 VanDerWaalsContact O-N 3.17Å; H7-G10 PolarHBondContact O-N 2.89Å; H7-Y12 HydrophobicContact CB-CD1 3.9Å; H7-Y12 HydrophobicContact CB-CE1 3.93Å; H7-W351 HydrophobicContact CB-CD2 4.06Å; H7-W351 HydrophobicContact CB-CE3 4.24Å; H7-W351 HydrophobicContact CB-CG 4.28Å; H7-W351 VanDerWaalsContact O-CB 3.29Å; H7-W351 WeakPolarHBondContact O-CB 3.3Å; H7-D446 VanDerWaalsContact NE2-CB 3.33Å; H7-D446 WeakPolarHBondContact NE2-CB 3.47Å; H7-D446 IonicContact NE2-OD2 2.69Å; H7-E465 IonicContact ND1-OE1 3.95Å; H7-Y467 AromaticContact CE1-CE1 3.85Å; H7-Y467 AromaticContact ND1-CE1 3.66Å
8P94.5Very high85.4Confident109 Ų10970.8 Ų70.871%0.70838%0.383SS*.THydrogen-bonded Turntrans-62.9-26.2-172.128-36.1000113.4E6 G10E6-P8 VanDerWaalsContact O-CD 3.32Å; E6-P8 WeakPolarHBondContact O-CD 3.45Å; P8-G10 PolarHBondContact O-N 2.88Å
9A94.2Very high86Confident77 Ų7767.9 Ų67.964%0.63637%0.368SS*.THydrogen-bonded Turntrans-69.1-18.5175.300000112.8H7 S11 E465H7-A9 PolarHBondContact O-N 3.47Å; H7-A9 VanDerWaalsContact O-N 3.17Å; A9-S11 PolarHBondContact O-N 3.34Å; A9-E465 WeakPolarHBondContact CB-OE2 3.4Å
10G94.4Very high86.6Confident7 Ų772.7 Ų72.77%0.07239%0.388CS..  trans64.824.1176.100000113.7H7 P8 Y12 K13H7-G10 PolarHBondContact O-N 2.89Å; P8-G10 PolarHBondContact O-N 2.88Å; G10-Y12 PolarHBondContact O-N 2.6Å; G10-K13 WeakPolarHBondContact O-CD 3.37Å; G10-K13 WeakPolarHBondContact O-CG 3.38Å; G10-K13 PolarHBondContact O-N 2.82Å
11S95.5Very high87.1Confident19 Ų1972.6 Ų72.613%0.13339%0.385CS..G310 helixtrans-72.2-15.1-172.973.30000113A9 K13 K14 E465 Y467 P494A9-S11 PolarHBondContact O-N 3.34Å; S11-K13 PolarHBondContact O-N 3.27Å; S11-K14 WeakPolarHBondContact O-CB 3.35Å; S11-K14 WeakPolarHBondContact O-CG 3.17Å; S11-K14 PolarHBondContact O-N 2.88Å; S11-E465 VanDerWaalsContact CB-OE2 3.25Å; S11-E465 WeakPolarHBondContact CB-OE2 3.49Å; S11-E465 PolarHBondContact OG-OE2 2.82Å; S11-Y467 VanDerWaalsContact OG-CE2 3.23Å; S11-Y467 WeakPolarHBondContact OG-CE2 3.01Å; S11-Y467 PolarHBondContact OG-OH 3.03Å; S11-P494 WeakPolarHBondContact O-CG 3.4Å
12Y96.6Very high90.1Very high0 Ų062.2 Ų62.20%033%0.334CS..G310 helixtrans-53-25.6170.453.5-100.1000112.9H7 G10 K14 I15 F16 L347 A349 W351 V354 I444 Y467H7-Y12 HydrophobicContact CB-CD1 3.9Å; H7-Y12 HydrophobicContact CB-CE1 3.93Å; G10-Y12 PolarHBondContact O-N 2.6Å; Y12-K14 PolarHBondContact O-N 2.63Å; Y12-I15 WeakPolarHBondContact O-CG1 3.37Å; Y12-I15 PolarHBondContact O-N 2.84Å; Y12-F16 HydrophobicContact CD2-CE2 4.37Å; Y12-L347 WeakPolarHBondContact CD2-O 3.32Å; Y12-L347 VanDerWaalsContact CE2-O 3.24Å; Y12-L347 WeakPolarHBondContact CE2-O 3.22Å; Y12-A349 PolarHBondContact OH-O 2.9Å; Y12-W351 HydrophobicContact CE1-CB 4.34Å; Y12-W351 AromaticContact CE1-CE3 3.99Å; Y12-W351 HydrophobicContact CE1-CE3 3.99Å; Y12-W351 VanDerWaalsContact OH-CA 3.26Å; Y12-W351 WeakPolarHBondContact OH-CA 3.41Å; Y12-W351 PolarHBondContact OH-N 3.39Å; Y12-V354 HydrophobicContact CE2-CG2 4.2Å; Y12-V354 WeakPolarHBondContact OH-CG2 3.4Å; Y12-I444 HydrophobicContact CD1-CG1 4.43Å; Y12-I444 HydrophobicContact CD1-CG2 4.07Å; Y12-I444 HydrophobicContact CD2-CD1 3.75Å; Y12-I444 HydrophobicContact CD2-CG1 4.4Å; Y12-I444 HydrophobicContact CE2-CD1 4.08Å; Y12-I444 HydrophobicContact CG-CD1 4.07Å; Y12-I444 HydrophobicContact CG-CG1 4.33Å; Y12-I444 HydrophobicContact CG-CG2 3.92Å; Y12-Y467 VanDerWaalsContact CA-CZ 3.5Å; Y12-Y467 HydrophobicContact CD1-CE1 4.3Å; Y12-Y467 HydrophobicContact CG-CE1 4.43Å; Y12-Y467 VanDerWaalsContact N-CE2 3.29Å; Y12-Y467 PolarHBondContact N-OH 3.15Å
13K97.3Very high92.8Very high57 Ų5760.6 Ų60.625%0.24834%0.336CS..G310 helixtrans-52-30.4177-65.4175.7-167.2-164.10112.7G10 S11 I15 F16 R348 A349 N350G10-K13 WeakPolarHBondContact O-CD 3.37Å; G10-K13 WeakPolarHBondContact O-CG 3.38Å; G10-K13 PolarHBondContact O-N 2.82Å; S11-K13 PolarHBondContact O-N 3.27Å; K13-I15 VanDerWaalsContact C-N 3.25Å; K13-I15 PolarHBondContact O-N 2.9Å; K13-F16 PolarHBondContact O-N 2.84Å; K13-R348 WeakPolarHBondContact CD-O 3.49Å; K13-R348 WeakPolarHBondContact CE-O 3.37Å; K13-R348 PolarHBondContact NZ-O 3.42Å; K13-A349 VanDerWaalsContact CE-O 3.32Å; K13-A349 WeakPolarHBondContact CE-O 3.24Å; K13-N350 PolarHBondContact NZ-OD1 3.37Å
14K96.8Very high95Very high84 Ų8462.4 Ų62.437%0.36533%0.332SS..G310 helixtrans-63.7-25.1179.9-66.4-77.1168.9-147.10113.9S11 Y12 F16 E17 P494S11-K14 WeakPolarHBondContact O-CB 3.35Å; S11-K14 WeakPolarHBondContact O-CG 3.17Å; S11-K14 PolarHBondContact O-N 2.88Å; Y12-K14 PolarHBondContact O-N 2.63Å; K14-F16 PolarHBondContact O-N 3.24Å; K14-E17 WeakPolarHBondContact CD-OE1 3.45Å; K14-E17 WeakPolarHBondContact CD-OE2 3.46Å; K14-E17 WeakPolarHBondContact CE-OE1 3.4Å; K14-E17 IonicContact NZ-OE1 3.29Å; K14-E17 PolarHBondContact NZ-OE1 3.09Å; K14-E17 IonicContact NZ-OE2 2.82Å; K14-E17 PolarHBondContact NZ-OE2 3.41Å; K14-E17 PolarHBondContact O-N 2.73Å; K14-P494 HydrophobicContact CB-CB 3.82Å; K14-P494 HydrophobicContact CB-CG 4.06Å; K14-P494 HydrophobicContact CG-CB 3.61Å; K14-P494 HydrophobicContact CG-CG 4.13Å
15I97.3Very high96Very high4 Ų458 Ų582%0.02132%0.324CS..G310 helixtrans-75-9.3175.381.5-165.4000112Y12 K13 P445 Y467 A492 P523 V524Y12-I15 WeakPolarHBondContact O-CG1 3.37Å; Y12-I15 PolarHBondContact O-N 2.84Å; K13-I15 VanDerWaalsContact C-N 3.25Å; K13-I15 PolarHBondContact O-N 2.9Å; I15-P445 HydrophobicContact CD1-CG 3.82Å; I15-Y467 HydrophobicContact CG2-CD2 4.34Å; I15-Y467 HydrophobicContact CG2-CG 4.44Å; I15-A492 HydrophobicContact CG2-CB 3.52Å; I15-P523 CarbonylContact O-C 3.54Å; I15-P523 WeakPolarHBondContact O-CA 3.37Å; I15-P523 WeakPolarHBondContact O-CB 3.48Å; I15-V524 HydrophobicContact CB-CB 4.25Å; I15-V524 HydrophobicContact CG1-CB 4.1Å; I15-V524 PolarHBondContact O-N 2.88Å
16F98.1Very high96.5Very high5 Ų557.7 Ų57.72%0.02233%0.325CS..G310 helixtrans-112.223.7177.1-47.6-63.3000111.9Y12 K13 K14 F50 L60 L344 L347 R348 V524Y12-F16 HydrophobicContact CD2-CE2 4.37Å; K13-F16 PolarHBondContact O-N 2.84Å; K14-F16 PolarHBondContact O-N 3.24Å; F16-F50 VanDerWaalsContact C-CE2 3.48Å; F16-F50 WeakPolarHBondContact O-CD2 3.16Å; F16-L60 HydrophobicContact CD1-CD1 4.04Å; F16-L60 HydrophobicContact CE1-CD1 3.83Å; F16-L344 HydrophobicContact CB-CD2 4.1Å; F16-L344 HydrophobicContact CD1-CD2 4.12Å; F16-L344 HydrophobicContact CG-CD2 4.29Å; F16-L347 HydrophobicContact CD2-CB 4.23Å; F16-L347 HydrophobicContact CE1-CB 4.4Å; F16-L347 HydrophobicContact CE1-CD1 4.07Å; F16-L347 HydrophobicContact CE2-CB 3.76Å; F16-L347 HydrophobicContact CZ-CB 3.85Å; F16-L347 HydrophobicContact CZ-CD1 4.13Å; F16-L347 HydrophobicContact CZ-CG 4.41Å; F16-R348 HydrophobicContact CB-CG 4.01Å; F16-R348 HydrophobicContact CD2-CG 4.11Å; F16-R348 HydrophobicContact CG-CG 4.41Å; F16-R348 VanDerWaalsContact O-CZ 3.26Å; F16-R348 PolarHBondContact O-NE 2.94Å; F16-R348 VanDerWaalsContact O-NE 3.16Å; F16-R348 PolarHBondContact O-NH2 3.34Å; F16-V524 HydrophobicContact CD1-CG1 4.11Å; F16-V524 HydrophobicContact CE1-CB 4.47Å; F16-V524 HydrophobicContact CE1-CG1 4.22Å
17E97.4Very high96.7Very high81 Ų8159.3 Ų59.338%0.37934%0.342SS..SBendtrans-105.4144.7178.2-72.5-178.8-166.800111.5K14 F50K14-E17 WeakPolarHBondContact CD-OE1 3.45Å; K14-E17 WeakPolarHBondContact CD-OE2 3.46Å; K14-E17 WeakPolarHBondContact CE-OE1 3.4Å; K14-E17 IonicContact NZ-OE1 3.29Å; K14-E17 PolarHBondContact NZ-OE1 3.09Å; K14-E17 IonicContact NZ-OE2 2.82Å; K14-E17 PolarHBondContact NZ-OE2 3.41Å; K14-E17 PolarHBondContact O-N 2.73Å; E17-F50 VanDerWaalsContact C-CD2 3.49Å; E17-F50 WeakPolarHBondContact O-CE2 3.25Å
18T98.3Very high96.8Very high51 Ų5160.3 Ų60.331%0.31335%0.348SS..  trans-60.2142.6176.8-69.30000110.8G48 L49 F50 E51T18-G48 WeakPolarHBondContact CA-O 3.21Å; T18-L49 HydrophobicContact CG2-CD1 3.42Å; T18-L49 VanDerWaalsContact CG2-CD1 3.42Å; T18-F50 PolarHBondContact OG1-N 3.23Å; T18-E51 WeakPolarHBondContact CB-OE1 3.42Å; T18-E51 PolarHBondContact OG1-OE1 2.95Å; T18-E51 PolarHBondContact OG1-OE2 2.95Å
19C96.6Very high96.9Very high15 Ų1557.8 Ų57.810%0.10133%0.331CS..  trans-135.8151.3174.773.60000111.6G48 L66 R81 F83 P523C19-G48 PolarHBondContact N-O 2.71Å; C19-L66 WeakPolarHBondContact SG-CD2 3.34Å; C19-R81 PolarHBondContact SG-NH1 2.71Å; C19-F83 VanDerWaalsContact O-CZ 3.31Å; C19-F83 WeakPolarHBondContact O-CZ 3.39Å; C19-P523 VanDerWaalsContact SG-CD 3.6Å
20E97.1Very high97.1Very high163 Ų16356.7 Ų56.776%0.76232%0.316SS*.PPolyproline II helixtrans-83.2150.2179-61.2-175.9162.600111.5R81E20-R81 PolarHBondContact O-NE 3.23Å; E20-R81 PolarHBondContact O-NH2 3.29Å
21E96.9Very high97.2Very high72 Ų7259.9 Ų59.934%0.33633%0.334SS..PPolyproline II helixtrans-66161.1169.963.3-176.8-167.700112.2F83 R85E21-F83 HydrophobicContact CB-CD2 4.12Å; E21-F83 HydrophobicContact CB-CE2 4.49Å; E21-R85 IonicContact OE1-CZ 2.72Å; E21-R85 IonicContact OE1-NH2 2.76Å; E21-R85 PolarHBondContact OE1-NH2 2.72Å; E21-R85 IonicContact OE2-CZ 3.73Å; E21-R85 VanDerWaalsContact OE2-CZ 3.22Å; E21-R85 IonicContact OE2-NH1 3.69Å; E21-R85 PolarHBondContact OE2-NH1 2.99Å; E21-R85 IonicContact OE2-NH2 2.73Å; E21-R85 PolarHBondContact OE2-NH2 2.73Å
22L97.9Very high97.3Very high28 Ų2861.8 Ų61.815%0.14736%0.356CS..PPolyproline II helixtrans-99.6140.2177.4-64.2172000109.6L26 Y79 Y80 R81L22-L26 HydrophobicContact CD1-CD1 3.71Å; L22-L26 HydrophobicContact CD1-CG 3.89Å; L22-L26 HydrophobicContact CD2-CD1 3.77Å; L22-L26 HydrophobicContact CD2-CG 4.18Å; L22-L26 HydrophobicContact CG-CD1 4.41Å; L22-Y79 HydrophobicContact CD1-CD1 3.91Å; L22-Y79 HydrophobicContact CD1-CE1 3.86Å; L22-Y80 HydrophobicContact CB-CD2 3.84Å; L22-Y80 HydrophobicContact CB-CE2 3.94Å; L22-Y80 WeakPolarHBondContact O-CE2 3.47Å; L22-R81 HydrophobicContact CD1-CG 3.85Å; L22-R81 HydrophobicContact CG-CG 3.85Å; L22-R81 PolarHBondContact N-O 3.06Å; L22-R81 VanDerWaalsContact N-O 3.12Å
23A96.4Very high97.4Very high104 Ų10471.5 Ų71.586%0.8639%0.393SS*.SBendtrans-76-31.5174.800000112.2
24E96.6Very high97.4Very high144 Ų14469.2 Ų69.267%0.67338%0.383SS*.SBendtrans-144.7158.6179.163.3-173.7165.700111.2L26E24-L26 PolarHBondContact O-N 2.84Å
25P97.9Very high97.4Very high65 Ų6566.3 Ų66.342%0.42237%0.373SS..PPolyproline II helixtrans-61130.1175-23.234.4000112.2Y79 Y80P25-Y79 CarbonylContact C-O 3.5Å; P25-Y79 WeakPolarHBondContact CA-O 3.32Å; P25-Y80 HydrophobicContact CB-CD2 4.48Å; P25-Y80 HydrophobicContact CB-CG 4.49Å; P25-Y80 HydrophobicContact CG-CD2 4.15Å; P25-Y80 HydrophobicContact CG-CG 4.12Å
26L97.5Very high97.3Very high52 Ų5270.6 Ų70.627%0.27240%0.403SS..EExtended strand (participates in β ladder)trans-82.2137.7175.6-63.5177.1000110.7L22 E24 T78 Y79L22-L26 HydrophobicContact CD1-CD1 3.71Å; L22-L26 HydrophobicContact CD1-CG 3.89Å; L22-L26 HydrophobicContact CD2-CD1 3.77Å; L22-L26 HydrophobicContact CD2-CG 4.18Å; L22-L26 HydrophobicContact CG-CD1 4.41Å; E24-L26 PolarHBondContact O-N 2.84Å; L26-T78 CarbonylContact O-C 3.53Å; L26-T78 VanDerWaalsContact O-CA 3.28Å; L26-T78 WeakPolarHBondContact O-CA 3.33Å; L26-T78 WeakPolarHBondContact O-CB 3.29Å; L26-Y79 PolarHBondContact N-O 2.89Å; L26-Y79 PolarHBondContact O-N 3.12Å
27P96.9Very high97.2Very high109 Ų10972.8 Ų72.871%0.70841%0.413SS*.EExtended strand (participates in β ladder)trans-66.5150165.930.7-33.9000109.8
28T97.9Very high97.1Very high21 Ų2169 Ų6913%0.12940%0.395CS..  trans-106156.8171.866.70000110.9F70 V77 A516 E517 V518T28-F70 HydrophobicContact CG2-CE1 4.32Å; T28-V77 WeakPolarHBondContact CB-O 3.38Å; T28-V77 HydrophobicContact CG2-CB 4.4Å; T28-V77 HydrophobicContact CG2-CG1 4.31Å; T28-V77 WeakPolarHBondContact CG2-O 3.33Å; T28-V77 PolarHBondContact N-O 3.01Å; T28-V77 WeakPolarHBondContact OG1-CB 3.2Å; T28-V77 PolarHBondContact OG1-O 2.82Å; T28-A516 HydrophobicContact CG2-CB 4.2Å; T28-A516 WeakPolarHBondContact OG1-CB 3.26Å; T28-E517 CarbonylContact C-O 3.58Å; T28-E517 VanDerWaalsContact CA-O 3.25Å; T28-E517 WeakPolarHBondContact CA-O 3.25Å; T28-E517 WeakPolarHBondContact CB-O 3.42Å; T28-V518 HydrophobicContact CG2-CG1 3.69Å
29T97.5Very high97.1Very high56 Ų5672.3 Ų72.334%0.34441%0.406SS..EExtended strand (participates in β ladder)trans-95.3119.8165.9-58.50000109.6R498 E517T29-R498 PolarHBondContact OG1-NH2 3.23Å; T29-E517 PolarHBondContact N-O 3.05Å; T29-E517 PolarHBondContact O-N 3.48Å
30V97.7Very high97.1Very high54 Ų5472.1 Ų72.133%0.32741%0.406SS..EExtended strand (participates in β ladder)trans-93127.5-176.8176.40000110.6I34 R515 A516V30-I34 HydrophobicContact CG1-CD1 3.96Å; V30-I34 HydrophobicContact CG1-CG1 3.83Å; V30-I34 HydrophobicContact CG2-CG1 4.41Å; V30-R515 WeakPolarHBondContact CA-O 3.2Å; V30-A516 HydrophobicContact CG2-CB 4.26Å
31T97.5Very high97.1Very high74 Ų7464.7 Ų64.745%0.45437%0.372SS..EExtended strand (participates in β ladder)trans-112.3138.7166-60.80000108.6A514 R515T31-A514 CarbonylContact O-C 3.12Å; T31-A514 WeakPolarHBondContact O-CA 3.47Å; T31-A514 WeakPolarHBondContact O-CB 3.11Å; T31-R515 PolarHBondContact N-O 3.2Å; T31-R515 PolarHBondContact O-N 2.81Å
32G97.6Very high97.2Very high58 Ų5861.4 Ų61.460%0.59836%0.357SS*.EExtended strand (participates in β ladder)trans82.8-157.5-171.400000112.7
33R97.8Very high97.3Very high204 Ų20460 Ų6077%0.7735%0.35SS*.  trans-129.2110-178.4-174.1-178.7-177.8-155.70.4111.1P35 I513R33-P35 WeakPolarHBondContact O-CD 3.35Å; R33-I513 PolarHBondContact N-O 2.84Å; R33-I513 WeakPolarHBondContact O-CG2 2.98Å
34I98.1Very high97.4Very high10 Ų1055.1 Ų55.15%0.05131%0.309CS..  trans-59124.4173.7-50.5-63.2000109.2V30 S36 L38 F72 G75 V77 I504 A514V30-I34 HydrophobicContact CG1-CD1 3.96Å; V30-I34 HydrophobicContact CG1-CG1 3.83Å; V30-I34 HydrophobicContact CG2-CG1 4.41Å; I34-S36 PolarHBondContact O-N 3.13Å; I34-L38 HydrophobicContact CG2-CB 4.42Å; I34-L38 HydrophobicContact CG2-CD1 4.32Å; I34-F72 HydrophobicContact CG2-CD1 4.09Å; I34-G75 WeakPolarHBondContact CG1-O 3.49Å; I34-V77 HydrophobicContact CD1-CG2 3.92Å; I34-V77 HydrophobicContact CG1-CG2 4.13Å; I34-I504 HydrophobicContact CD1-CD1 3.49Å; I34-I504 VanDerWaalsContact CD1-CD1 3.49Å; I34-I504 HydrophobicContact CG2-CD1 4.2Å; I34-A514 HydrophobicContact CD1-CB 3.78Å
35P96.7Very high97.5Very high23 Ų2348.3 Ų48.315%0.14928%0.277CS..  trans-55.7133175.8-25.732.2000112.1R33 F37 L38 V486 I513R33-P35 WeakPolarHBondContact O-CD 3.35Å; P35-F37 HydrophobicContact CB-CD1 3.71Å; P35-F37 HydrophobicContact CB-CE1 3.43Å; P35-F37 VanDerWaalsContact CB-CE1 3.43Å; P35-F37 HydrophobicContact CB-CG 4.49Å; P35-F37 HydrophobicContact CB-CZ 4.01Å; P35-F37 HydrophobicContact CG-CE1 4.28Å; P35-F37 PolarHBondContact O-N 3.38Å; P35-F37 VanDerWaalsContact O-N 3.13Å; P35-L38 HydrophobicContact CB-CD1 4.37Å; P35-L38 HydrophobicContact CB-CG 4.26Å; P35-L38 HydrophobicContact CG-CD1 4.16Å; P35-L38 WeakPolarHBondContact O-CB 3.3Å; P35-L38 PolarHBondContact O-N 3.23Å; P35-V486 HydrophobicContact CG-CG1 4.24Å; P35-I513 HydrophobicContact CG-CG2 4.09Å
36S95.1Very high97.5Very high94 Ų9445.2 Ų45.266%0.65726%0.257SS*.THydrogen-bonded Turntrans-67.3-16.8-17454.10000114.5I34 K39I34-S36 PolarHBondContact O-N 3.13Å; S36-K39 VanDerWaalsContact O-CE 3.3Å; S36-K39 WeakPolarHBondContact O-CE 3.19Å
37F95.3Very high97.5Very high50 Ų5042.7 Ų42.722%0.21924%0.244CC..THydrogen-bonded Turntrans-81-17.4175.771.5-99.5000112.7P35 K39 V474 T476 P477 V486P35-F37 HydrophobicContact CB-CD1 3.71Å; P35-F37 HydrophobicContact CB-CE1 3.43Å; P35-F37 VanDerWaalsContact CB-CE1 3.43Å; P35-F37 HydrophobicContact CB-CG 4.49Å; P35-F37 HydrophobicContact CB-CZ 4.01Å; P35-F37 HydrophobicContact CG-CE1 4.28Å; P35-F37 PolarHBondContact O-N 3.38Å; P35-F37 VanDerWaalsContact O-N 3.13Å; F37-K39 PolarHBondContact O-N 2.94Å; F37-V474 HydrophobicContact CE2-CG1 4.3Å; F37-T476 HydrophobicContact CD1-CG2 4.27Å; F37-T476 HydrophobicContact CE1-CG2 4.13Å; F37-P477 HydrophobicContact CB-CG 3.83Å; F37-P477 HydrophobicContact CG-CG 4.33Å; F37-V486 HydrophobicContact CE2-CG2 4.33Å; F37-V486 HydrophobicContact CZ-CG1 4.1Å; F37-V486 HydrophobicContact CZ-CG2 4.11Å
38L96.6Very high97.6Very high2 Ų237.5 Ų37.51%0.0121%0.21CC..  trans-7397.8173-68179.7000109.1I34 P35 F72 V474 V486 L488 I504 Y530I34-L38 HydrophobicContact CG2-CB 4.42Å; I34-L38 HydrophobicContact CG2-CD1 4.32Å; P35-L38 HydrophobicContact CB-CD1 4.37Å; P35-L38 HydrophobicContact CB-CG 4.26Å; P35-L38 HydrophobicContact CG-CD1 4.16Å; P35-L38 WeakPolarHBondContact O-CB 3.3Å; P35-L38 PolarHBondContact O-N 3.23Å; L38-F72 HydrophobicContact CB-CB 4.37Å; L38-F72 HydrophobicContact CB-CD1 4.36Å; L38-F72 HydrophobicContact CB-CG 4.44Å; L38-F72 HydrophobicContact CD1-CD1 4.41Å; L38-F72 HydrophobicContact CD1-CE1 4.43Å; L38-V474 HydrophobicContact CD2-CB 4.19Å; L38-V474 HydrophobicContact CD2-CG1 3.82Å; L38-V486 HydrophobicContact CD1-CG2 4.17Å; L38-V486 HydrophobicContact CD2-CG2 3.93Å; L38-V486 HydrophobicContact CG-CG2 4.41Å; L38-L488 HydrophobicContact CD1-CD2 4.07Å; L38-I504 HydrophobicContact CD1-CD1 3.84Å; L38-I504 HydrophobicContact CD1-CG2 4.32Å; L38-Y530 WeakPolarHBondContact CA-OH 3.17Å; L38-Y530 HydrophobicContact CD2-CE1 4.48Å
39K96.7Very high97.6Very high121 Ų12137.6 Ų37.653%0.52621%0.209SC..  trans-134.4116.2173.9-62.7176.9-176.2174.10105.8S36 F37 F72 Y530S36-K39 VanDerWaalsContact O-CE 3.3Å; S36-K39 WeakPolarHBondContact O-CE 3.19Å; F37-K39 PolarHBondContact O-N 2.94Å; K39-F72 WeakPolarHBondContact CA-O 3.36Å; K39-Y530 PolarHBondContact N-OH 3.15Å; K39-Y530 PolarHBondContact O-OH 2.81Å
40G97Very high97.7Very high11 Ų1134.9 Ų34.911%0.11319%0.193CC..EExtended strand (participates in β ladder)trans144.7-172.8-171.100000111.8F72 K531G40-F72 PolarHBondContact N-O 2.91Å; G40-F72 WeakPolarHBondContact O-CD2 3.23Å; G40-F72 PolarHBondContact O-N 2.83Å; G40-K531 CarbonylContact C-O 3.56Å; G40-K531 WeakPolarHBondContact CA-O 3.49Å
41S98.3Very high97.7Very high7 Ų735.7 Ų35.75%0.04919%0.193CC..EExtended strand (participates in β ladder)trans-122.8129.5-176.7-54.40000111.5F70 D71 K531S41-F70 CarbonylContact C-O 3.55Å; S41-F70 WeakPolarHBondContact CA-O 3.44Å; S41-D71 PolarHBondContact OG-OD1 3.02Å; S41-K531 PolarHBondContact N-O 3.21Å; S41-K531 PolarHBondContact O-N 3.45Å
42L98.6Very high97.6Very high2 Ų232.5 Ų32.51%0.0117%0.173CC..EExtended strand (participates in β ladder)trans-80.6125160.3178.176.1000108.7R44 K69 F70 F72 L472 L488 I490 M502 Y530L42-R44 HydrophobicContact CD1-CG 4.36Å; L42-R44 HydrophobicContact CD2-CG 4.29Å; L42-R44 HydrophobicContact CG-CG 4.15Å; L42-K69 CarbonylContact O-C 3.5Å; L42-K69 VanDerWaalsContact O-CA 3.26Å; L42-K69 WeakPolarHBondContact O-CA 3.37Å; L42-F70 HydrophobicContact CB-CB 4.31Å; L42-F70 PolarHBondContact N-O 2.64Å; L42-F70 PolarHBondContact O-N 2.91Å; L42-F72 HydrophobicContact CB-CE2 4.1Å; L42-L472 HydrophobicContact CD1-CB 4.38Å; L42-L472 HydrophobicContact CD1-CD1 3.29Å; L42-L472 HydrophobicContact CD1-CG 4.17Å; L42-L488 HydrophobicContact CD1-CB 4.41Å; L42-L488 HydrophobicContact CD1-CD1 4.49Å; L42-L488 HydrophobicContact CD2-CB 4.45Å; L42-I490 HydrophobicContact CD2-CG1 4.33Å; L42-M502 HydrophobicContact CD2-CE 3.07Å; L42-M502 HydrophobicContact CD2-SD 3.97Å; L42-M502 HydrophobicContact CG-CE 4.45Å; L42-Y530 HydrophobicContact CB-CD2 4.37Å
43L98.8Very high97.3Very high0 Ų032.6 Ų32.60%018%0.175CC..EExtended strand (participates in β ladder)trans-115.8132.4176.3-56.9165.6000108.9M67 H68 K69 V137 T158 L161 G528 M529 K531L43-M67 HydrophobicContact CB-CE 4.05Å; L43-M67 HydrophobicContact CD1-CE 4.17Å; L43-M67 HydrophobicContact CD2-CE 3.85Å; L43-M67 HydrophobicContact CG-CE 4.24Å; L43-H68 CarbonylContact C-O 3.48Å; L43-H68 VanDerWaalsContact CA-O 3.31Å; L43-H68 WeakPolarHBondContact CA-O 3.34Å; L43-K69 HydrophobicContact CD2-CB 4.03Å; L43-K69 HydrophobicContact CD2-CD 3.93Å; L43-K69 HydrophobicContact CD2-CG 3.74Å; L43-V137 HydrophobicContact CB-CG1 3.96Å; L43-T158 HydrophobicContact CD1-CG2 3.41Å; L43-T158 VanDerWaalsContact CD1-CG2 3.41Å; L43-L161 HydrophobicContact CD2-CD2 4.08Å; L43-G528 CarbonylContact O-C 3.57Å; L43-G528 WeakPolarHBondContact O-CA 3.47Å; L43-M529 HydrophobicContact CB-CG 4.43Å; L43-M529 HydrophobicContact CD1-CG 4.3Å; L43-M529 PolarHBondContact N-O 3Å; L43-M529 PolarHBondContact O-N 2.71Å; L43-K531 HydrophobicContact CD1-CB 4.43Å
44R98.5Very high97Very high1 Ų131 Ų310%0.00418%0.181CC..EExtended strand (participates in β ladder)trans-139.8152.6177.3-63.8-170.359.875.13.3111.6L42 M67 H68 S469 E470 I490 T525 F526 H527L42-R44 HydrophobicContact CD1-CG 4.36Å; L42-R44 HydrophobicContact CD2-CG 4.29Å; L42-R44 HydrophobicContact CG-CG 4.15Å; R44-M67 WeakPolarHBondContact O-CA 3.27Å; R44-H68 HydrophobicContact CB-CB 4.47Å; R44-H68 PolarHBondContact N-O 3.17Å; R44-H68 PolarHBondContact O-N 3.11Å; R44-S469 PolarHBondContact NE-OG 3.13Å; R44-E470 IonicContact CZ-OE2 2.7Å; R44-E470 IonicContact NH1-OE2 3.61Å; R44-E470 PolarHBondContact NH1-OE2 2.86Å; R44-E470 IonicContact NH2-OE2 3.17Å; R44-I490 HydrophobicContact CB-CD1 4.39Å; R44-I490 HydrophobicContact CG-CD1 4.37Å; R44-T525 HydrophobicContact CB-CG2 4.27Å; R44-T525 PolarHBondContact NE-OG1 2.93Å; R44-T525 PolarHBondContact NH2-O 2.48Å; R44-T525 PolarHBondContact NH2-OG1 3.25Å; R44-F526 PolarHBondContact NH2-O 3.08Å; R44-H527 WeakPolarHBondContact CA-O 3.43Å
45L98.7Very high96.8Very high0 Ų033.9 Ų33.90%020%0.195CC..EExtended strand (participates in β ladder)trans-121.8149.5176.2-82152.2000111.3M67 V84 L134 N136 V137 A146 T525 F526 H527L45-M67 HydrophobicContact CD2-CB 3.91Å; L45-M67 HydrophobicContact CD2-CG 4.23Å; L45-M67 HydrophobicContact CG-CG 4.35Å; L45-V84 HydrophobicContact CD2-CG2 3.89Å; L45-L134 CarbonylContact C-O 3.51Å; L45-L134 WeakPolarHBondContact CB-O 3.31Å; L45-N136 WeakPolarHBondContact CD1-O 3.4Å; L45-V137 HydrophobicContact CD1-CB 3.65Å; L45-V137 HydrophobicContact CD1-CG1 4.07Å; L45-A146 HydrophobicContact CD1-CB 3.67Å; L45-A146 HydrophobicContact CD2-CB 4.45Å; L45-T525 CarbonylContact O-C 3.48Å; L45-T525 WeakPolarHBondContact O-CA 3.29Å; L45-T525 WeakPolarHBondContact O-CB 3.49Å; L45-F526 PolarHBondContact O-N 3.05Å; L45-H527 PolarHBondContact N-O 3.26Å
46G98.6Very high96.8Very high0 Ų035.2 Ų35.20%020%0.204CC..EExtended strand (participates in β ladder)trans-173.2176.2174.800000111.3L66 L134G46-L66 PolarHBondContact N-O 3.36Å; G46-L66 PolarHBondContact O-N 2.87Å; G46-L134 WeakPolarHBondContact CA-O 3.46Å; G46-L134 PolarHBondContact N-O 3.3Å
47P98.6Very high97Very high0 Ų030.9 Ų30.90%017%0.173CC..EExtended strand (participates in β ladder)trans-72.2131.117429.6-34.1000110.9F50 L134 P523 V524 F526P47-F50 HydrophobicContact CB-CD1 4.43Å; P47-F50 HydrophobicContact CB-CE1 3.66Å; P47-F50 HydrophobicContact CB-CZ 3.78Å; P47-F50 HydrophobicContact CG-CE1 3.68Å; P47-F50 HydrophobicContact CG-CZ 3.69Å; P47-F50 WeakPolarHBondContact O-CZ 3.34Å; P47-L134 HydrophobicContact CB-CD1 4.12Å; P47-P523 WeakPolarHBondContact O-CB 3.29Å; P47-P523 WeakPolarHBondContact O-CG 3.47Å; P47-V524 HydrophobicContact CG-CG1 3.76Å; P47-F526 HydrophobicContact CG-CE2 4.36Å; P47-F526 HydrophobicContact CG-CZ 4.16Å
48G98.1Very high97.1Very high0 Ų034.3 Ų34.30%019%0.185CC..EExtended strand (participates in β ladder)trans-120.1-13.2177.900000115.8T18 C19 Q64T18-G48 WeakPolarHBondContact CA-O 3.21Å; C19-G48 PolarHBondContact N-O 2.71Å; G48-Q64 PolarHBondContact N-O 3.23Å
49L98.5Very high97.2Very high22 Ų2234.2 Ų34.212%0.11519%0.185CC..EExtended strand (participates in β ladder)trans-132.2114.1178.5178.866.2000108.1T18 E51 V52 G63 Q64 F83 Y89 I93T18-L49 HydrophobicContact CG2-CD1 3.42Å; T18-L49 VanDerWaalsContact CG2-CD1 3.42Å; L49-E51 WeakPolarHBondContact CD1-O 3.14Å; L49-E51 VanDerWaalsContact CG-O 3.29Å; L49-E51 WeakPolarHBondContact CG-O 3.34Å; L49-V52 HydrophobicContact CD2-CG2 4.39Å; L49-G63 CarbonylContact O-C 3.56Å; L49-G63 WeakPolarHBondContact O-CA 3.33Å; L49-Q64 HydrophobicContact CB-CB 4.07Å; L49-Q64 HydrophobicContact CB-CG 4.32Å; L49-Q64 HydrophobicContact CD2-CB 4.49Å; L49-Q64 HydrophobicContact CD2-CG 4.11Å; L49-Q64 PolarHBondContact O-N 2.77Å; L49-F83 HydrophobicContact CB-CE1 3.66Å; L49-F83 HydrophobicContact CB-CZ 3.85Å; L49-Y89 HydrophobicContact CD2-CE2 4.25Å; L49-I93 HydrophobicContact CD2-CD1 3.91Å
50F98.4Very high97.3Very high0 Ų029.2 Ų29.20%016%0.164CC..  trans-105.23.3-172.7-62-90.2000113.7F16 E17 T18 P47 F57 L344 R348 P523F16-F50 VanDerWaalsContact C-CE2 3.48Å; F16-F50 WeakPolarHBondContact O-CD2 3.16Å; E17-F50 VanDerWaalsContact C-CD2 3.49Å; E17-F50 WeakPolarHBondContact O-CE2 3.25Å; T18-F50 PolarHBondContact OG1-N 3.23Å; P47-F50 HydrophobicContact CB-CD1 4.43Å; P47-F50 HydrophobicContact CB-CE1 3.66Å; P47-F50 HydrophobicContact CB-CZ 3.78Å; P47-F50 HydrophobicContact CG-CE1 3.68Å; P47-F50 HydrophobicContact CG-CZ 3.69Å; P47-F50 WeakPolarHBondContact O-CZ 3.34Å; F50-F57 WeakPolarHBondContact O-CB 3.37Å; F50-F57 PolarHBondContact O-N 3.38Å; F50-L344 HydrophobicContact CD1-CD1 3.76Å; F50-L344 HydrophobicContact CD1-CD2 4.01Å; F50-L344 HydrophobicContact CE1-CD1 4.48Å; F50-L344 HydrophobicContact CE1-CD2 4Å; F50-R348 VanDerWaalsContact CG-NH2 3.34Å; F50-P523 HydrophobicContact CE2-CB 4.22Å; F50-P523 HydrophobicContact CZ-CB 4.44Å
51E98.1Very high97.3Very high70 Ų7030.2 Ų30.233%0.32717%0.165SC..EExtended strand (participates in β ladder)trans-155.9153.6176.158.3-76.9161.800110.5T18 L49 E55T18-E51 WeakPolarHBondContact CB-OE1 3.42Å; T18-E51 PolarHBondContact OG1-OE1 2.95Å; T18-E51 PolarHBondContact OG1-OE2 2.95Å; L49-E51 WeakPolarHBondContact CD1-O 3.14Å; L49-E51 VanDerWaalsContact CG-O 3.29Å; L49-E51 WeakPolarHBondContact CG-O 3.34Å; E51-E55 CarbonylContact C-O 3.56Å; E51-E55 VanDerWaalsContact CA-O 3.3Å; E51-E55 WeakPolarHBondContact CA-O 3.48Å
52V96.4Very high97.3Very high7 Ų729.9 Ų29.94%0.04216%0.163CC..EExtended strand (participates in β ladder)trans-125.6100.8174.6-172.70000108.2L49 D54 E55 F57 A92 V98L49-V52 HydrophobicContact CD2-CG2 4.39Å; V52-D54 PolarHBondContact O-N 3.02Å; V52-E55 PolarHBondContact N-O 2.72Å; V52-E55 PolarHBondContact O-N 2.66Å; V52-F57 HydrophobicContact CG2-CE2 3.8Å; V52-F57 HydrophobicContact CG2-CZ 4Å; V52-A92 HydrophobicContact CG1-CB 4.26Å; V52-A92 WeakPolarHBondContact CG1-O 3.14Å; V52-A92 HydrophobicContact CG2-CB 4.05Å; V52-V98 HydrophobicContact CB-CG2 4.45Å; V52-V98 HydrophobicContact CG2-CG2 4.27Å
53G90.4Very high97.3Very high61 Ų6129.8 Ų29.863%0.62916%0.162SC*.THydrogen-bonded Turntrans64.3-122.1-168.900000110.3
54D90.4Very high97.3Very high169 Ų16929.9 Ų29.990%0.90416%0.162SC*.THydrogen-bonded Turntrans-92.2-0.3178.1-61.1-42.7000113.3V52 P56V52-D54 PolarHBondContact O-N 3.02Å; D54-P56 WeakPolarHBondContact O-CD 3.25Å
55E95.1Very high97.3Very high72 Ų7229.9 Ų29.934%0.33616%0.163SC..EExtended strand (participates in β ladder)trans-93.8111.6-178.9-66-175.4-172.800111.1E51 V52 V98E51-E55 CarbonylContact C-O 3.56Å; E51-E55 VanDerWaalsContact CA-O 3.3Å; E51-E55 WeakPolarHBondContact CA-O 3.48Å; V52-E55 PolarHBondContact N-O 2.72Å; V52-E55 PolarHBondContact O-N 2.66Å; E55-V98 HydrophobicContact CB-CG2 4.07Å; E55-V98 WeakPolarHBondContact OE2-CB 3.2Å; E55-V98 PolarHBondContact OE2-N 3.18Å
56P97Very high97.3Very high51 Ų5129.9 Ų29.933%0.33116%0.163SC..EExtended strand (participates in β ladder)trans-81.5149.4179.433.4-35.5000112.2D54 Y58D54-P56 WeakPolarHBondContact O-CD 3.25Å; P56-Y58 HydrophobicContact CG-CD1 4.46Å; P56-Y58 HydrophobicContact CG-CE1 3.72Å
57F98.1Very high97.3Very high3 Ų329.9 Ų29.91%0.01316%0.163CC..  trans-81.1142.4158.2-70.7-61000110F50 V52 D62 Q64 V98 E102 T105 L344F50-F57 WeakPolarHBondContact O-CB 3.37Å; F50-F57 PolarHBondContact O-N 3.38Å; V52-F57 HydrophobicContact CG2-CE2 3.8Å; V52-F57 HydrophobicContact CG2-CZ 4Å; F57-D62 HydrophobicContact CB-CB 3.69Å; F57-D62 HydrophobicContact CD1-CB 3.72Å; F57-D62 HydrophobicContact CG-CB 3.92Å; F57-Q64 HydrophobicContact CE2-CG 3.91Å; F57-Q64 HydrophobicContact CZ-CG 4.17Å; F57-V98 HydrophobicContact CD1-CG2 4.35Å; F57-V98 HydrophobicContact CE1-CB 4.41Å; F57-V98 HydrophobicContact CE1-CG1 3.77Å; F57-V98 HydrophobicContact CE1-CG2 3.7Å; F57-V98 HydrophobicContact CZ-CG1 4.33Å; F57-V98 HydrophobicContact CZ-CG2 3.85Å; F57-E102 HydrophobicContact CD1-CG 4.21Å; F57-E102 HydrophobicContact CE1-CG 3.69Å; F57-T105 WeakPolarHBondContact CA-OG1 3.16Å; F57-T105 HydrophobicContact CD1-CG2 3.98Å; F57-T105 HydrophobicContact CE1-CG2 4.41Å; F57-L344 WeakPolarHBondContact O-CD1 3.47Å
58Y98Very high97.3Very high122 Ų12230 Ų3048%0.47816%0.163SC..  trans-102.8-36.8-169.3-64.2-64.7000112.8P56 D62 T105 L344P56-Y58 HydrophobicContact CG-CD1 4.46Å; P56-Y58 HydrophobicContact CG-CE1 3.72Å; Y58-D62 PolarHBondContact N-OD2 3.13Å; Y58-T105 HydrophobicContact CD2-CG2 4.08Å; Y58-T105 WeakPolarHBondContact CD2-OG1 3.33Å; Y58-T105 HydrophobicContact CE2-CG2 4.23Å; Y58-T105 PolarHBondContact N-OG1 3.39Å; Y58-L344 WeakPolarHBondContact O-CB 3.21Å; Y58-L344 PolarHBondContact O-N 3.23Å
59H98.5Very high97.4Very high0 Ų030.8 Ų30.80%017%0.167CC..BIsolated β-bridgetrans-104.1154.6-176.2-159.9-90.3000112.4F61 D62 F103 Y339 W343 L344H59-F61 AromaticContact CE1-CD2 3.27Å; H59-F61 WeakPolarHBondContact CE1-CD2 3.36Å; H59-F61 AromaticContact CE1-CE2 3.65Å; H59-F61 AromaticContact ND1-CD2 3.34Å; H59-F61 VanDerWaalsContact ND1-CD2 3.34Å; H59-F61 WeakPolarHBondContact ND1-CD2 3.47Å; H59-F61 AromaticContact ND1-CG 3.94Å; H59-F61 PolarHBondContact ND1-N 3.04Å; H59-F61 PolarHBondContact O-N 3.04Å; H59-F61 VanDerWaalsContact O-N 3.08Å; H59-D62 WeakPolarHBondContact CA-OD2 3.37Å; H59-D62 WeakPolarHBondContact CB-OD2 3.39Å; H59-D62 PolarHBondContact N-OD2 2.65Å; H59-D62 WeakPolarHBondContact O-CB 3.44Å; H59-D62 PolarHBondContact O-N 2.97Å; H59-D62 VanDerWaalsContact O-N 3.09Å; H59-F103 HydrophobicContact CB-CD1 4.27Å; H59-F103 AromaticContact CE1-CD1 3.75Å; H59-F103 AromaticContact CE1-CE1 3.59Å; H59-F103 AromaticContact CG-CD1 3.7Å; H59-F103 AromaticContact ND1-CD1 3.42Å; H59-F103 WeakPolarHBondContact ND1-CD1 3.41Å; H59-F103 AromaticContact ND1-CE1 3.76Å; H59-F103 AromaticContact NE2-CE1 3.79Å; H59-Y339 PolarHBondContact NE2-O 3.09Å; H59-W343 HydrophobicContact CB-CE3 4.06Å; H59-W343 HydrophobicContact CB-CZ3 4.04Å; H59-W343 AromaticContact CD2-CD2 3.94Å; H59-W343 AromaticContact CD2-CE3 3.95Å; H59-L344 WeakPolarHBondContact O-CD1 3.28Å
60L98.4Very high97.4Very high16 Ų1629.7 Ų29.78%0.08416%0.161CC..THydrogen-bonded Turntrans-54.7-27.6176.917859000113.5F16 L342 L347 V524 F526F16-L60 HydrophobicContact CD1-CD1 4.04Å; F16-L60 HydrophobicContact CE1-CD1 3.83Å; L60-L342 HydrophobicContact CB-CB 4.21Å; L60-L342 VanDerWaalsContact CB-O 3.3Å; L60-L342 WeakPolarHBondContact CB-O 3.44Å; L60-L342 HydrophobicContact CD2-CB 4.36Å; L60-L342 HydrophobicContact CD2-CD1 4.31Å; L60-L342 HydrophobicContact CD2-CD2 4.49Å; L60-L342 PolarHBondContact N-O 3.45Å; L60-L347 HydrophobicContact CB-CD1 4.02Å; L60-L347 HydrophobicContact CD1-CD1 4.24Å; L60-L347 HydrophobicContact CD2-CD1 4.01Å; L60-L347 HydrophobicContact CG-CD1 4.31Å; L60-V524 HydrophobicContact CD1-CG1 3.93Å; L60-F526 HydrophobicContact CD1-CE1 4.12Å; L60-F526 HydrophobicContact CD1-CZ 4.01Å; L60-F526 HydrophobicContact CD2-CE1 3.99Å; L60-F526 HydrophobicContact CD2-CZ 4.36Å; L60-F526 HydrophobicContact CG-CE1 3.9Å; L60-F526 HydrophobicContact CG-CZ 3.77Å
61F98.2Very high97.4Very high32 Ų3231.8 Ų31.814%0.1417%0.172CC..THydrogen-bonded Turntrans-96.912.3-176.8-56.2-58.6000114H59 F103 Y339 L342 F526H59-F61 AromaticContact CE1-CD2 3.27Å; H59-F61 WeakPolarHBondContact CE1-CD2 3.36Å; H59-F61 AromaticContact CE1-CE2 3.65Å; H59-F61 AromaticContact ND1-CD2 3.34Å; H59-F61 VanDerWaalsContact ND1-CD2 3.34Å; H59-F61 WeakPolarHBondContact ND1-CD2 3.47Å; H59-F61 AromaticContact ND1-CG 3.94Å; H59-F61 PolarHBondContact ND1-N 3.04Å; H59-F61 PolarHBondContact O-N 3.04Å; H59-F61 VanDerWaalsContact O-N 3.08Å; F61-F103 HydrophobicContact CB-CB 4.15Å; F61-F103 HydrophobicContact CB-CD1 4.39Å; F61-F103 HydrophobicContact CB-CG 4.35Å; F61-F103 HydrophobicContact CD2-CD1 4.3Å; F61-F103 HydrophobicContact CD2-CE1 4.48Å; F61-Y339 HydrophobicContact CD2-CD2 4.02Å; F61-Y339 AromaticContact CD2-CE2 3.87Å; F61-Y339 HydrophobicContact CD2-CE2 3.87Å; F61-Y339 AromaticContact CE2-CD1 3.79Å; F61-Y339 HydrophobicContact CE2-CD1 3.79Å; F61-Y339 AromaticContact CE2-CD2 3.69Å; F61-Y339 HydrophobicContact CE2-CD2 3.69Å; F61-Y339 AromaticContact CE2-CE1 3.48Å; F61-Y339 HydrophobicContact CE2-CE1 3.48Å; F61-Y339 VanDerWaalsContact CE2-CE1 3.48Å; F61-Y339 AromaticContact CE2-CE2 3.44Å; F61-Y339 HydrophobicContact CE2-CE2 3.44Å; F61-Y339 VanDerWaalsContact CE2-CE2 3.44Å; F61-Y339 AromaticContact CE2-CG 3.89Å; F61-Y339 HydrophobicContact CE2-CG 3.89Å; F61-Y339 AromaticContact CE2-CZ 3.34Å; F61-Y339 HydrophobicContact CZ-CD1 4.44Å; F61-Y339 AromaticContact CZ-CE1 3.8Å; F61-Y339 HydrophobicContact CZ-CE1 3.8Å; F61-Y339 HydrophobicContact CZ-CE2 4.24Å; F61-Y339 AromaticContact CZ-CZ 3.72Å; F61-L342 HydrophobicContact CE2-CD1 3.97Å; F61-L342 HydrophobicContact CZ-CD1 4.09Å; F61-F526 HydrophobicContact CD1-CD2 4.49Å; F61-F526 HydrophobicContact CD1-CE1 4.29Å; F61-F526 AromaticContact CD1-CE2 3.71Å; F61-F526 HydrophobicContact CD1-CE2 3.71Å; F61-F526 AromaticContact CD1-CZ 3.61Å; F61-F526 HydrophobicContact CD1-CZ 3.61Å; F61-F526 HydrophobicContact CE1-CD1 4.35Å; F61-F526 HydrophobicContact CE1-CD2 4.49Å; F61-F526 AromaticContact CE1-CE1 3.84Å; F61-F526 HydrophobicContact CE1-CE1 3.84Å; F61-F526 AromaticContact CE1-CE2 3.97Å; F61-F526 HydrophobicContact CE1-CE2 3.97Å; F61-F526 AromaticContact CE1-CZ 3.64Å; F61-F526 HydrophobicContact CE1-CZ 3.64Å
62D98.3Very high97.4Very high0 Ų028.6 Ų28.60%016%0.157CC..THydrogen-bonded Turntrans-101.4-26.1-176-65.9-15.7000113.5F57 Y58 H59 Q64 E102 F103 G104 T105 N132F57-D62 HydrophobicContact CB-CB 3.69Å; F57-D62 HydrophobicContact CD1-CB 3.72Å; F57-D62 HydrophobicContact CG-CB 3.92Å; Y58-D62 PolarHBondContact N-OD2 3.13Å; H59-D62 WeakPolarHBondContact CA-OD2 3.37Å; H59-D62 WeakPolarHBondContact CB-OD2 3.39Å; H59-D62 PolarHBondContact N-OD2 2.65Å; H59-D62 WeakPolarHBondContact O-CB 3.44Å; H59-D62 PolarHBondContact O-N 2.97Å; H59-D62 VanDerWaalsContact O-N 3.09Å; D62-Q64 PolarHBondContact O-NE2 3.19Å; D62-E102 HydrophobicContact CB-CB 3.9Å; D62-E102 HydrophobicContact CB-CG 4.45Å; D62-E102 WeakPolarHBondContact OD1-CB 3.3Å; D62-F103 WeakPolarHBondContact OD1-CA 3.45Å; D62-F103 VanDerWaalsContact OD1-CB 3.29Å; D62-F103 WeakPolarHBondContact OD1-CB 3.35Å; D62-F103 PolarHBondContact OD1-N 3.34Å; D62-G104 PolarHBondContact OD1-N 3.05Å; D62-G104 VanDerWaalsContact OD2-C 3.31Å; D62-G104 WeakPolarHBondContact OD2-CA 3.49Å; D62-G104 PolarHBondContact OD2-N 3.43Å; D62-T105 PolarHBondContact OD2-N 2.92Å; D62-T105 VanDerWaalsContact OD2-N 3.09Å; D62-T105 PolarHBondContact OD2-OG1 2.86Å; D62-N132 PolarHBondContact O-ND2 2.78Å
63G98.2Very high97.4Very high0 Ų035 Ų350%018%0.184CC..SBendtrans-61.6146.9-176.300000111.9L49 N132 L134L49-G63 CarbonylContact O-C 3.56Å; L49-G63 WeakPolarHBondContact O-CA 3.33Å; G63-N132 PolarHBondContact O-ND2 2.94Å; G63-L134 WeakPolarHBondContact O-CD1 3.31Å
64Q98.8Very high97.4Very high1 Ų138.3 Ų38.31%0.00519%0.188CC..EExtended strand (participates in β ladder)trans-69.6138.5-172.2-56.4-66-67.700111.9G48 L49 F57 D62 L66 F83 A88 Y89 E102G48-Q64 PolarHBondContact N-O 3.23Å; L49-Q64 HydrophobicContact CB-CB 4.07Å; L49-Q64 HydrophobicContact CB-CG 4.32Å; L49-Q64 HydrophobicContact CD2-CB 4.49Å; L49-Q64 HydrophobicContact CD2-CG 4.11Å; L49-Q64 PolarHBondContact O-N 2.77Å; F57-Q64 HydrophobicContact CE2-CG 3.91Å; F57-Q64 HydrophobicContact CZ-CG 4.17Å; D62-Q64 PolarHBondContact O-NE2 3.19Å; Q64-L66 PolarHBondContact O-N 3Å; Q64-F83 HydrophobicContact CB-CD1 4.5Å; Q64-A88 VanDerWaalsContact OE1-C 3.32Å; Q64-Y89 HydrophobicContact CB-CD2 3.81Å; Q64-Y89 HydrophobicContact CG-CD2 4.14Å; Q64-Y89 VanDerWaalsContact OE1-CA 3.22Å; Q64-Y89 VanDerWaalsContact OE1-N 3.09Å; Q64-E102 PolarHBondContact NE2-OE1 3.17Å
65A98.8Very high97.5Very high1 Ų131.8 Ų31.81%0.00816%0.16CC..EExtended strand (participates in β ladder)trans-57.4120.9-173.600000113F83 V84 N132 L134A65-F83 WeakPolarHBondContact O-CA 3.34Å; A65-V84 HydrophobicContact CB-CB 4.06Å; A65-V84 HydrophobicContact CB-CG2 3.96Å; A65-V84 PolarHBondContact O-N 3.4Å; A65-N132 VanDerWaalsContact CB-OD1 3.29Å; A65-N132 WeakPolarHBondContact CB-OD1 3.35Å; A65-N132 PolarHBondContact N-OD1 2.81Å; A65-L134 HydrophobicContact CB-CB 3.77Å
66L98.9Very high97.5Very high0 Ų035.2 Ų35.20%018%0.176CC..EExtended strand (participates in β ladder)trans-118123175.6-178.366.3000109.6C19 G46 Q64 H68 R81 F83 P523C19-L66 WeakPolarHBondContact SG-CD2 3.34Å; G46-L66 PolarHBondContact N-O 3.36Å; G46-L66 PolarHBondContact O-N 2.87Å; Q64-L66 PolarHBondContact O-N 3Å; L66-H68 WeakPolarHBondContact CD2-CE1 3.44Å; L66-H68 WeakPolarHBondContact CD2-NE2 3.49Å; L66-H68 PolarHBondContact O-CD2 2.82Å; L66-R81 HydrophobicContact CD1-CB 4.17Å; L66-R81 HydrophobicContact CG-CB 4.43Å; L66-F83 HydrophobicContact CB-CD1 4.13Å; L66-F83 HydrophobicContact CB-CE1 4.12Å; L66-F83 HydrophobicContact CD1-CD1 3.98Å; L66-F83 HydrophobicContact CD1-CD2 4.17Å; L66-F83 HydrophobicContact CD1-CE1 4.11Å; L66-F83 HydrophobicContact CD1-CE2 4.29Å; L66-F83 HydrophobicContact CD1-CG 4Å; L66-F83 HydrophobicContact CD1-CZ 4.26Å; L66-P523 HydrophobicContact CD2-CG 4.02Å
67M98.8Very high97.6Very high1 Ų133 Ų331%0.00516%0.162CC..EExtended strand (participates in β ladder)trans-95131.3177.5-165.8176.9-177.200109.6L43 R44 L45 R81 K82 V84 V137 V156 T158 L161L43-M67 HydrophobicContact CB-CE 4.05Å; L43-M67 HydrophobicContact CD1-CE 4.17Å; L43-M67 HydrophobicContact CD2-CE 3.85Å; L43-M67 HydrophobicContact CG-CE 4.24Å; R44-M67 WeakPolarHBondContact O-CA 3.27Å; L45-M67 HydrophobicContact CD2-CB 3.91Å; L45-M67 HydrophobicContact CD2-CG 4.23Å; L45-M67 HydrophobicContact CG-CG 4.35Å; M67-R81 CarbonylContact O-C 3.54Å; M67-R81 WeakPolarHBondContact O-CA 3.47Å; M67-R81 WeakPolarHBondContact O-CB 3.47Å; M67-K82 PolarHBondContact N-O 2.98Å; M67-K82 PolarHBondContact O-N 2.92Å; M67-V84 HydrophobicContact CB-CG2 4.3Å; M67-V137 HydrophobicContact CE-CG1 4.3Å; M67-V137 HydrophobicContact CE-CG2 4.19Å; M67-V156 HydrophobicContact CE-CG2 4.14Å; M67-V156 HydrophobicContact SD-CB 4.34Å; M67-V156 HydrophobicContact SD-CG2 4.11Å; M67-T158 HydrophobicContact CE-CG2 4.26Å; M67-L161 HydrophobicContact CE-CD2 3.94Å; M67-L161 HydrophobicContact CG-CD2 4.12Å; M67-L161 HydrophobicContact SD-CD2 3.74Å
68H98.8Very high97.6Very high1 Ų135 Ų351%0.00518%0.175CC..EExtended strand (participates in β ladder)trans-113.2141.4-179.3-59.2-93.9000110L43 R44 L66 Y79 Y80 I490 T525L43-H68 CarbonylContact C-O 3.48Å; L43-H68 VanDerWaalsContact CA-O 3.31Å; L43-H68 WeakPolarHBondContact CA-O 3.34Å; R44-H68 HydrophobicContact CB-CB 4.47Å; R44-H68 PolarHBondContact N-O 3.17Å; R44-H68 PolarHBondContact O-N 3.11Å; L66-H68 WeakPolarHBondContact CD2-CE1 3.44Å; L66-H68 WeakPolarHBondContact CD2-NE2 3.49Å; L66-H68 PolarHBondContact O-CD2 2.82Å; H68-Y79 HydrophobicContact CB-CE2 4.23Å; H68-Y79 AromaticContact ND1-CE2 3.94Å; H68-Y79 AromaticContact ND1-CZ 3.84Å; H68-Y79 PolarHBondContact ND1-OH 2.96Å; H68-Y80 CarbonylContact C-O 3.51Å; H68-I490 HydrophobicContact CB-CD1 4.44Å; H68-T525 VanDerWaalsContact CD2-CG2 3.47Å; H68-T525 WeakPolarHBondContact CD2-CG2 3.34Å
69K98.8Very high97.6Very high17 Ų1729.2 Ų29.27%0.07415%0.152CC..EExtended strand (participates in β ladder)trans-132.9125.7175.3-171.6174.384.2162.90111.3L42 L43 Y79 Y80 T158 D159 L161L42-K69 CarbonylContact O-C 3.5Å; L42-K69 VanDerWaalsContact O-CA 3.26Å; L42-K69 WeakPolarHBondContact O-CA 3.37Å; L43-K69 HydrophobicContact CD2-CB 4.03Å; L43-K69 HydrophobicContact CD2-CD 3.93Å; L43-K69 HydrophobicContact CD2-CG 3.74Å; K69-Y79 CarbonylContact O-C 3.6Å; K69-Y79 WeakPolarHBondContact O-CA 3.43Å; K69-Y79 WeakPolarHBondContact O-CD2 3.15Å; K69-Y80 PolarHBondContact N-O 2.71Å; K69-Y80 PolarHBondContact O-N 3.26Å; K69-T158 WeakPolarHBondContact CD-O 3.19Å; K69-D159 PolarHBondContact NZ-O 2.87Å; K69-L161 HydrophobicContact CB-CD1 3.91Å; K69-L161 HydrophobicContact CB-CD2 4.05Å; K69-L161 HydrophobicContact CB-CG 4.4Å; K69-L161 HydrophobicContact CD-CD2 4.25Å
70F98.8Very high97.6Very high0 Ų030.3 Ų30.30%016%0.156CC..EExtended strand (participates in β ladder)trans-108.6117.6160.4-78.1-94.1000108.8T28 S41 L42 F72 V77 T78 Y79 I490 M502 V518 I522T28-F70 HydrophobicContact CG2-CE1 4.32Å; S41-F70 CarbonylContact C-O 3.55Å; S41-F70 WeakPolarHBondContact CA-O 3.44Å; L42-F70 HydrophobicContact CB-CB 4.31Å; L42-F70 PolarHBondContact N-O 2.64Å; L42-F70 PolarHBondContact O-N 2.91Å; F70-F72 HydrophobicContact CB-CE2 4.15Å; F70-F72 HydrophobicContact CB-CZ 4.41Å; F70-F72 WeakPolarHBondContact O-CE2 3.39Å; F70-V77 HydrophobicContact CB-CG1 4.25Å; F70-V77 HydrophobicContact CD1-CG1 3.79Å; F70-T78 CarbonylContact C-O 3.32Å; F70-T78 VanDerWaalsContact CA-O 3.28Å; F70-T78 WeakPolarHBondContact CA-O 3.33Å; F70-Y79 HydrophobicContact CD1-CD2 4.25Å; F70-Y79 AromaticContact CD2-CD2 3.73Å; F70-Y79 HydrophobicContact CD2-CD2 3.73Å; F70-Y79 HydrophobicContact CD2-CE2 4.26Å; F70-Y79 AromaticContact CE1-CD2 3.91Å; F70-Y79 HydrophobicContact CE1-CD2 3.91Å; F70-Y79 HydrophobicContact CE1-CG 4.05Å; F70-Y79 AromaticContact CE2-CD2 3.32Å; F70-Y79 HydrophobicContact CE2-CD2 3.32Å; F70-Y79 AromaticContact CE2-CE2 3.67Å; F70-Y79 HydrophobicContact CE2-CE2 3.67Å; F70-Y79 HydrophobicContact CE2-CG 4.22Å; F70-Y79 HydrophobicContact CG-CD2 4.19Å; F70-Y79 AromaticContact CZ-CD2 3.43Å; F70-Y79 HydrophobicContact CZ-CD2 3.43Å; F70-Y79 VanDerWaalsContact CZ-CD2 3.43Å; F70-Y79 HydrophobicContact CZ-CE2 4.04Å; F70-Y79 AromaticContact CZ-CG 3.87Å; F70-Y79 HydrophobicContact CZ-CG 3.87Å; F70-I490 HydrophobicContact CD2-CD1 4.16Å; F70-I490 HydrophobicContact CD2-CG1 4.2Å; F70-I490 HydrophobicContact CE2-CD1 3.83Å; F70-I490 HydrophobicContact CE2-CG1 3.83Å; F70-I490 HydrophobicContact CE2-CG2 4.47Å; F70-M502 HydrophobicContact CB-CE 4.02Å; F70-M502 HydrophobicContact CD1-CB 3.58Å; F70-M502 HydrophobicContact CD1-CE 4.27Å; F70-M502 HydrophobicContact CD1-CG 4.25Å; F70-M502 HydrophobicContact CD2-CE 3.43Å; F70-M502 VanDerWaalsContact CD2-CE 3.43Å; F70-M502 HydrophobicContact CE1-CB 3.58Å; F70-M502 HydrophobicContact CE2-CE 3.86Å; F70-M502 HydrophobicContact CG-CB 4.05Å; F70-M502 HydrophobicContact CG-CE 3.65Å; F70-M502 HydrophobicContact CG-CG 4.37Å; F70-M502 HydrophobicContact CZ-CB 4.07Å; F70-M502 HydrophobicContact CZ-CE 4.44Å; F70-V518 HydrophobicContact CE1-CG1 4.17Å; F70-V518 HydrophobicContact CZ-CG1 4.46Å; F70-I522 HydrophobicContact CE2-CD1 3.98Å; F70-I522 HydrophobicContact CZ-CD1 3.78Å
71D98.6Very high97.6Very high43 Ų4330.2 Ų30.223%0.2316%0.155CC..EExtended strand (participates in β ladder)trans-105.4125.7-176-164.537.9000110.9S41 V77 T78S41-D71 PolarHBondContact OG-OD1 3.02Å; D71-V77 VanDerWaalsContact O-CA 3.25Å; D71-V77 WeakPolarHBondContact O-CA 3.47Å; D71-T78 PolarHBondContact N-O 2.9Å; D71-T78 PolarHBondContact O-N 2.88Å
72F98.4Very high97.7Very high3 Ų330.6 Ų30.61%0.01316%0.156CC..EExtended strand (participates in β ladder)trans-105.9116.8-174.8-59.4-97.6000109.8I34 L38 K39 G40 L42 F70 V77 L488 M502 I504 Y530I34-F72 HydrophobicContact CG2-CD1 4.09Å; L38-F72 HydrophobicContact CB-CB 4.37Å; L38-F72 HydrophobicContact CB-CD1 4.36Å; L38-F72 HydrophobicContact CB-CG 4.44Å; L38-F72 HydrophobicContact CD1-CD1 4.41Å; L38-F72 HydrophobicContact CD1-CE1 4.43Å; K39-F72 WeakPolarHBondContact CA-O 3.36Å; G40-F72 PolarHBondContact N-O 2.91Å; G40-F72 WeakPolarHBondContact O-CD2 3.23Å; G40-F72 PolarHBondContact O-N 2.83Å; L42-F72 HydrophobicContact CB-CE2 4.1Å; F70-F72 HydrophobicContact CB-CE2 4.15Å; F70-F72 HydrophobicContact CB-CZ 4.41Å; F70-F72 WeakPolarHBondContact O-CE2 3.39Å; F72-V77 HydrophobicContact CD1-CG1 4.38Å; F72-V77 HydrophobicContact CD1-CG2 3.58Å; F72-V77 HydrophobicContact CE1-CG1 4.24Å; F72-V77 HydrophobicContact CE1-CG2 3.81Å; F72-V77 HydrophobicContact CG-CG2 4.43Å; F72-L488 HydrophobicContact CE2-CD1 4.2Å; F72-L488 HydrophobicContact CZ-CD1 4.22Å; F72-L488 HydrophobicContact CZ-CD2 4.29Å; F72-M502 HydrophobicContact CE1-CG 4.22Å; F72-M502 HydrophobicContact CZ-CG 3.78Å; F72-M502 HydrophobicContact CZ-SD 4.23Å; F72-I504 HydrophobicContact CE1-CD1 3.98Å; F72-Y530 AromaticContact CD2-CE2 3.94Å; F72-Y530 HydrophobicContact CD2-CE2 3.94Å; F72-Y530 HydrophobicContact CE2-CE2 4.13Å
73K95.6Very high97.7Very high141 Ų14131 Ų3161%0.61316%0.158SC*.EExtended strand (participates in β ladder)trans-145.9120.3179.7-168174.5-175.8175.20111.3G75 Q76K73-G75 PolarHBondContact O-N 3.28Å; K73-Q76 PolarHBondContact N-O 2.81Å; K73-Q76 WeakPolarHBondContact O-CB 3.24Å; K73-Q76 PolarHBondContact O-N 3.01Å
74N91.8Very high97.7Very high131 Ų13131.1 Ų31.170%0.70116%0.159SC*.THydrogen-bonded Turntrans52.439.1175.8-59.1-28.4000113.8Q76N74-Q76 PolarHBondContact O-N 2.84Å
75G91.6Very high97.7Very high32 Ų3235 Ų3533%0.3317%0.173SC..THydrogen-bonded Turntrans77.11.1-178.700000115.1I34 K73I34-G75 WeakPolarHBondContact CG1-O 3.49Å; K73-G75 PolarHBondContact O-N 3.28Å
76Q95.7Very high97.7Very high144 Ų14435.1 Ų35.167%0.67317%0.174SC*.EExtended strand (participates in β ladder)trans-97.7151.6169.8-61.6180-4.900110.1K73 N74K73-Q76 PolarHBondContact N-O 2.81Å; K73-Q76 WeakPolarHBondContact O-CB 3.24Å; K73-Q76 PolarHBondContact O-N 3.01Å; N74-Q76 PolarHBondContact O-N 2.84Å
77V98.4Very high97.6Very high4 Ų438.7 Ų38.72%0.02419%0.193CC..EExtended strand (participates in β ladder)trans-128.2134.3176.3-172.40000109.2T28 I34 F70 D71 F72 A516T28-V77 WeakPolarHBondContact CB-O 3.38Å; T28-V77 HydrophobicContact CG2-CB 4.4Å; T28-V77 HydrophobicContact CG2-CG1 4.31Å; T28-V77 WeakPolarHBondContact CG2-O 3.33Å; T28-V77 PolarHBondContact N-O 3.01Å; T28-V77 WeakPolarHBondContact OG1-CB 3.2Å; T28-V77 PolarHBondContact OG1-O 2.82Å; I34-V77 HydrophobicContact CD1-CG2 3.92Å; I34-V77 HydrophobicContact CG1-CG2 4.13Å; F70-V77 HydrophobicContact CB-CG1 4.25Å; F70-V77 HydrophobicContact CD1-CG1 3.79Å; D71-V77 VanDerWaalsContact O-CA 3.25Å; D71-V77 WeakPolarHBondContact O-CA 3.47Å; F72-V77 HydrophobicContact CD1-CG1 4.38Å; F72-V77 HydrophobicContact CD1-CG2 3.58Å; F72-V77 HydrophobicContact CE1-CG1 4.24Å; F72-V77 HydrophobicContact CE1-CG2 3.81Å; F72-V77 HydrophobicContact CG-CG2 4.43Å; V77-A516 HydrophobicContact CB-CB 3.72Å; V77-A516 HydrophobicContact CG1-CB 3.94Å; V77-A516 HydrophobicContact CG2-CB 3.92Å
78T98.5Very high97.6Very high46 Ų4638.8 Ų38.828%0.28219%0.194SC..EExtended strand (participates in β ladder)trans-116.2153.8169.164.60000110.5L26 F70 D71L26-T78 CarbonylContact O-C 3.53Å; L26-T78 VanDerWaalsContact O-CA 3.28Å; L26-T78 WeakPolarHBondContact O-CA 3.33Å; L26-T78 WeakPolarHBondContact O-CB 3.29Å; F70-T78 CarbonylContact C-O 3.32Å; F70-T78 VanDerWaalsContact CA-O 3.28Å; F70-T78 WeakPolarHBondContact CA-O 3.33Å; D71-T78 PolarHBondContact N-O 2.9Å; D71-T78 PolarHBondContact O-N 2.88Å
79Y98.8Very high97.6Very high0 Ų040 Ų400%020%0.198CC..EExtended strand (participates in β ladder)trans-119.8135.3177172.6-117.7000111L22 P25 L26 H68 K69 F70 R81 V518 I522L22-Y79 HydrophobicContact CD1-CD1 3.91Å; L22-Y79 HydrophobicContact CD1-CE1 3.86Å; P25-Y79 CarbonylContact C-O 3.5Å; P25-Y79 WeakPolarHBondContact CA-O 3.32Å; L26-Y79 PolarHBondContact N-O 2.89Å; L26-Y79 PolarHBondContact O-N 3.12Å; H68-Y79 HydrophobicContact CB-CE2 4.23Å; H68-Y79 AromaticContact ND1-CE2 3.94Å; H68-Y79 AromaticContact ND1-CZ 3.84Å; H68-Y79 PolarHBondContact ND1-OH 2.96Å; K69-Y79 CarbonylContact O-C 3.6Å; K69-Y79 WeakPolarHBondContact O-CA 3.43Å; K69-Y79 WeakPolarHBondContact O-CD2 3.15Å; F70-Y79 HydrophobicContact CD1-CD2 4.25Å; F70-Y79 AromaticContact CD2-CD2 3.73Å; F70-Y79 HydrophobicContact CD2-CD2 3.73Å; F70-Y79 HydrophobicContact CD2-CE2 4.26Å; F70-Y79 AromaticContact CE1-CD2 3.91Å; F70-Y79 HydrophobicContact CE1-CD2 3.91Å; F70-Y79 HydrophobicContact CE1-CG 4.05Å; F70-Y79 AromaticContact CE2-CD2 3.32Å; F70-Y79 HydrophobicContact CE2-CD2 3.32Å; F70-Y79 AromaticContact CE2-CE2 3.67Å; F70-Y79 HydrophobicContact CE2-CE2 3.67Å; F70-Y79 HydrophobicContact CE2-CG 4.22Å; F70-Y79 HydrophobicContact CG-CD2 4.19Å; F70-Y79 AromaticContact CZ-CD2 3.43Å; F70-Y79 HydrophobicContact CZ-CD2 3.43Å; F70-Y79 VanDerWaalsContact CZ-CD2 3.43Å; F70-Y79 HydrophobicContact CZ-CE2 4.04Å; F70-Y79 AromaticContact CZ-CG 3.87Å; F70-Y79 HydrophobicContact CZ-CG 3.87Å; Y79-R81 HydrophobicContact CE1-CG 4.29Å; Y79-R81 WeakPolarHBondContact OH-CD 3.42Å; Y79-V518 HydrophobicContact CD1-CB 4.45Å; Y79-V518 HydrophobicContact CD1-CG1 3.94Å; Y79-V518 HydrophobicContact CG-CG1 3.97Å; Y79-I522 HydrophobicContact CD2-CD1 4.34Å; Y79-I522 HydrophobicContact CE1-CD1 3.99Å; Y79-I522 HydrophobicContact CE1-CG1 4.13Å; Y79-I522 HydrophobicContact CE2-CD1 3.79Å; Y79-I522 HydrophobicContact CE2-CG1 4.49Å
80Y98.6Very high97.5Very high24 Ų2442.1 Ų42.19%0.09421%0.213CC..EExtended strand (participates in β ladder)trans-144.1148.8177.5-170.6-127.2000110.7L22 P25 H68 K69 T160 L161L22-Y80 HydrophobicContact CB-CD2 3.84Å; L22-Y80 HydrophobicContact CB-CE2 3.94Å; L22-Y80 WeakPolarHBondContact O-CE2 3.47Å; P25-Y80 HydrophobicContact CB-CD2 4.48Å; P25-Y80 HydrophobicContact CB-CG 4.49Å; P25-Y80 HydrophobicContact CG-CD2 4.15Å; P25-Y80 HydrophobicContact CG-CG 4.12Å; H68-Y80 CarbonylContact C-O 3.51Å; K69-Y80 PolarHBondContact N-O 2.71Å; K69-Y80 PolarHBondContact O-N 3.26Å; Y80-T160 WeakPolarHBondContact CE1-O 3.41Å; Y80-L161 HydrophobicContact CD1-CB 4.4Å; Y80-L161 HydrophobicContact CD1-CD1 3.47Å; Y80-L161 VanDerWaalsContact CD1-CD1 3.47Å; Y80-L161 HydrophobicContact CD1-CG 3.79Å; Y80-L161 HydrophobicContact CE1-CB 4.23Å; Y80-L161 HydrophobicContact CE1-CD1 4.04Å; Y80-L161 HydrophobicContact CE1-CG 4.11Å; Y80-L161 HydrophobicContact CG-CD1 4.24Å
81R98.6Very high97.4Very high14 Ų1445.3 Ų45.35%0.05323%0.225CC..EExtended strand (participates in β ladder)trans-148145.217558.6159.5-179.7-134.31.2112.4C19 E20 L22 L66 M67 Y79 S521C19-R81 PolarHBondContact SG-NH1 2.71Å; E20-R81 PolarHBondContact O-NE 3.23Å; E20-R81 PolarHBondContact O-NH2 3.29Å; L22-R81 HydrophobicContact CD1-CG 3.85Å; L22-R81 HydrophobicContact CG-CG 3.85Å; L22-R81 PolarHBondContact N-O 3.06Å; L22-R81 VanDerWaalsContact N-O 3.12Å; L66-R81 HydrophobicContact CD1-CB 4.17Å; L66-R81 HydrophobicContact CG-CB 4.43Å; M67-R81 CarbonylContact O-C 3.54Å; M67-R81 WeakPolarHBondContact O-CA 3.47Å; M67-R81 WeakPolarHBondContact O-CB 3.47Å; Y79-R81 HydrophobicContact CE1-CG 4.29Å; Y79-R81 WeakPolarHBondContact OH-CD 3.42Å; R81-S521 PolarHBondContact NH1-O 3.45Å
82K98.6Very high97.3Very high39 Ų3943.3 Ų43.317%0.1722%0.215CC..EExtended strand (participates in β ladder)trans-148.6138.7179.7-164166.5-177.51720110.7M67 L161 E162M67-K82 PolarHBondContact N-O 2.98Å; M67-K82 PolarHBondContact O-N 2.92Å; K82-L161 HydrophobicContact CB-CB 3.87Å; K82-L161 HydrophobicContact CB-CD1 4.49Å; K82-E162 IonicContact NZ-OE1 2.66Å
83F98.8Very high97.2Very high9 Ų947 Ų474%0.03923%0.233CC..EExtended strand (participates in β ladder)trans-67.2137.5174-72.4-80.4000110.4C19 E21 L49 Q64 A65 L66 R85 Y89C19-F83 VanDerWaalsContact O-CZ 3.31Å; C19-F83 WeakPolarHBondContact O-CZ 3.39Å; E21-F83 HydrophobicContact CB-CD2 4.12Å; E21-F83 HydrophobicContact CB-CE2 4.49Å; L49-F83 HydrophobicContact CB-CE1 3.66Å; L49-F83 HydrophobicContact CB-CZ 3.85Å; Q64-F83 HydrophobicContact CB-CD1 4.5Å; A65-F83 WeakPolarHBondContact O-CA 3.34Å; L66-F83 HydrophobicContact CB-CD1 4.13Å; L66-F83 HydrophobicContact CB-CE1 4.12Å; L66-F83 HydrophobicContact CD1-CD1 3.98Å; L66-F83 HydrophobicContact CD1-CD2 4.17Å; L66-F83 HydrophobicContact CD1-CE1 4.11Å; L66-F83 HydrophobicContact CD1-CE2 4.29Å; L66-F83 HydrophobicContact CD1-CG 4Å; L66-F83 HydrophobicContact CD1-CZ 4.26Å; F83-R85 PolarHBondContact O-N 3.02Å; F83-R85 PolarHBondContact O-NH1 3.26Å; F83-Y89 HydrophobicContact CB-CD1 4.47Å; F83-Y89 HydrophobicContact CB-CD2 4.09Å; F83-Y89 HydrophobicContact CB-CE1 4.04Å; F83-Y89 HydrophobicContact CB-CE2 3.6Å; F83-Y89 HydrophobicContact CB-CG 4.49Å; F83-Y89 HydrophobicContact CD1-CD2 4.15Å; F83-Y89 AromaticContact CD1-CE2 3.7Å; F83-Y89 HydrophobicContact CD1-CE2 3.7Å; F83-Y89 AromaticContact CD2-CE2 3.91Å; F83-Y89 HydrophobicContact CD2-CE2 3.91Å; F83-Y89 AromaticContact CD2-CZ 3.91Å; F83-Y89 WeakPolarHBondContact CD2-OH 3.18Å; F83-Y89 HydrophobicContact CE1-CE2 4.32Å; F83-Y89 HydrophobicContact CG-CD2 4.2Å; F83-Y89 AromaticContact CG-CE2 3.47Å; F83-Y89 HydrophobicContact CG-CE2 3.47Å; F83-Y89 VanDerWaalsContact CG-CE2 3.47Å; F83-Y89 AromaticContact CG-CZ 3.73Å
84V98.7Very high97.2Very high2 Ų245.3 Ų45.31%0.01224%0.235CC..  trans-71.2122.7172.7-169.90000107.7L45 A65 M67 T86 T154 V156 T163L45-V84 HydrophobicContact CD2-CG2 3.89Å; A65-V84 HydrophobicContact CB-CB 4.06Å; A65-V84 HydrophobicContact CB-CG2 3.96Å; A65-V84 PolarHBondContact O-N 3.4Å; M67-V84 HydrophobicContact CB-CG2 4.3Å; V84-T86 HydrophobicContact CB-CG2 4.11Å; V84-T86 HydrophobicContact CG1-CG2 3.73Å; V84-T86 PolarHBondContact O-N 3.07Å; V84-T154 HydrophobicContact CG1-CG2 3.65Å; V84-V156 HydrophobicContact CG1-CG1 4.32Å; V84-T163 HydrophobicContact CG1-CG2 4.32Å
85R98.5Very high97.2Very high83 Ų8342.4 Ų42.431%0.31322%0.217SC..  trans-78.962.2-177.5-55-56.7-163.3-110.510111.2E21 F83 V90 T163E21-R85 IonicContact OE1-CZ 2.72Å; E21-R85 IonicContact OE1-NH2 2.76Å; E21-R85 PolarHBondContact OE1-NH2 2.72Å; E21-R85 IonicContact OE2-CZ 3.73Å; E21-R85 VanDerWaalsContact OE2-CZ 3.22Å; E21-R85 IonicContact OE2-NH1 3.69Å; E21-R85 PolarHBondContact OE2-NH1 2.99Å; E21-R85 IonicContact OE2-NH2 2.73Å; E21-R85 PolarHBondContact OE2-NH2 2.73Å; F83-R85 PolarHBondContact O-N 3.02Å; F83-R85 PolarHBondContact O-NH1 3.26Å; R85-V90 HydrophobicContact CB-CG2 4.02Å; R85-T163 HydrophobicContact CB-CG2 4.13Å; R85-T163 PolarHBondContact N-OG1 2.97Å
86T98.5Very high97.3Very high3 Ų348.7 Ų48.72%0.01824%0.236CC..  trans-73.4165174.5610000110.7V84 A88 Y89 V90 D131V84-T86 HydrophobicContact CB-CG2 4.11Å; V84-T86 HydrophobicContact CG1-CG2 3.73Å; V84-T86 PolarHBondContact O-N 3.07Å; T86-A88 PolarHBondContact O-N 3Å; T86-Y89 PolarHBondContact O-N 3.4Å; T86-Y89 WeakPolarHBondContact OG1-CB 3.32Å; T86-Y89 PolarHBondContact OG1-N 3.41Å; T86-Y89 VanDerWaalsContact OG1-N 3.12Å; T86-V90 WeakPolarHBondContact O-CB 3.26Å; T86-V90 VanDerWaalsContact O-CG2 3.3Å; T86-V90 WeakPolarHBondContact O-CG2 3.38Å; T86-V90 PolarHBondContact O-N 3.03Å; T86-D131 WeakPolarHBondContact CB-OD1 3.44Å; T86-D131 WeakPolarHBondContact CG2-O 3.48Å
87D97.9Very high97.2Very high76 Ų7643.4 Ų43.441%0.40621%0.209SC..Hα-helixtrans-61.4-37.6173.6-67.4-23000110.4R91 I100 D131 K166D87-R91 WeakPolarHBondContact O-CB 3.45Å; D87-R91 WeakPolarHBondContact O-CG 3.45Å; D87-R91 PolarHBondContact O-N 3.18Å; D87-I100 HydrophobicContact CB-CD1 4.08Å; D87-D131 VanDerWaalsContact CB-OD2 3.29Å; D87-D131 WeakPolarHBondContact CB-OD2 3.48Å; D87-D131 PolarHBondContact N-OD1 2.93Å; D87-D131 PolarHBondContact N-OD2 3.12Å; D87-K166 IonicContact OD2-NZ 2.78Å; D87-K166 PolarHBondContact OD2-NZ 2.83Å
88A97.3Very high96.9Very high2 Ų243.4 Ų43.42%0.01721%0.209CC..Hα-helixtrans-55.3-52.4173.500000111.7Q64 T86 A92 I100 D131 N132Q64-A88 VanDerWaalsContact OE1-C 3.32Å; T86-A88 PolarHBondContact O-N 3Å; A88-A92 WeakPolarHBondContact O-CB 3.49Å; A88-A92 PolarHBondContact O-N 2.76Å; A88-I100 HydrophobicContact CB-CB 4.35Å; A88-I100 HydrophobicContact CB-CD1 4.3Å; A88-D131 PolarHBondContact N-OD1 2.97Å; A88-N132 HydrophobicContact CB-CB 4.24Å
89Y98.4Very high96.6Very high26 Ų2641.8 Ų41.810%0.10220%0.199CC..Hα-helixtrans-68.3-51-178.7179.6-95.9000112.1L49 Q64 F83 T86 R91 A92 I93L49-Y89 HydrophobicContact CD2-CE2 4.25Å; Q64-Y89 HydrophobicContact CB-CD2 3.81Å; Q64-Y89 HydrophobicContact CG-CD2 4.14Å; Q64-Y89 VanDerWaalsContact OE1-CA 3.22Å; Q64-Y89 VanDerWaalsContact OE1-N 3.09Å; F83-Y89 HydrophobicContact CB-CD1 4.47Å; F83-Y89 HydrophobicContact CB-CD2 4.09Å; F83-Y89 HydrophobicContact CB-CE1 4.04Å; F83-Y89 HydrophobicContact CB-CE2 3.6Å; F83-Y89 HydrophobicContact CB-CG 4.49Å; F83-Y89 HydrophobicContact CD1-CD2 4.15Å; F83-Y89 AromaticContact CD1-CE2 3.7Å; F83-Y89 HydrophobicContact CD1-CE2 3.7Å; F83-Y89 AromaticContact CD2-CE2 3.91Å; F83-Y89 HydrophobicContact CD2-CE2 3.91Å; F83-Y89 AromaticContact CD2-CZ 3.91Å; F83-Y89 WeakPolarHBondContact CD2-OH 3.18Å; F83-Y89 HydrophobicContact CE1-CE2 4.32Å; F83-Y89 HydrophobicContact CG-CD2 4.2Å; F83-Y89 AromaticContact CG-CE2 3.47Å; F83-Y89 HydrophobicContact CG-CE2 3.47Å; F83-Y89 VanDerWaalsContact CG-CE2 3.47Å; F83-Y89 AromaticContact CG-CZ 3.73Å; T86-Y89 PolarHBondContact O-N 3.4Å; T86-Y89 WeakPolarHBondContact OG1-CB 3.32Å; T86-Y89 PolarHBondContact OG1-N 3.41Å; T86-Y89 VanDerWaalsContact OG1-N 3.12Å; Y89-R91 VanDerWaalsContact C-N 3.33Å; Y89-R91 PolarHBondContact O-N 3.03Å; Y89-A92 PolarHBondContact O-N 2.97Å; Y89-I93 HydrophobicContact CD1-CG1 4.28Å; Y89-I93 HydrophobicContact CD2-CG1 4.21Å; Y89-I93 HydrophobicContact CE1-CG1 3.91Å; Y89-I93 HydrophobicContact CE2-CD1 4.14Å; Y89-I93 HydrophobicContact CE2-CG1 3.85Å; Y89-I93 HydrophobicContact CG-CG1 4.43Å; Y89-I93 WeakPolarHBondContact O-CG1 3.03Å; Y89-I93 PolarHBondContact O-N 2.9Å
90V98.3Very high96.2Very high62 Ų6242.1 Ų42.138%0.37620%0.201SC..Hα-helixtrans-61-43.7-175.1170.60000110.8R85 T86 T94R85-V90 HydrophobicContact CB-CG2 4.02Å; T86-V90 WeakPolarHBondContact O-CB 3.26Å; T86-V90 VanDerWaalsContact O-CG2 3.3Å; T86-V90 WeakPolarHBondContact O-CG2 3.38Å; T86-V90 PolarHBondContact O-N 3.03Å; V90-T94 VanDerWaalsContact O-CB 3.23Å; V90-T94 WeakPolarHBondContact O-CB 3.43Å; V90-T94 PolarHBondContact O-N 2.86Å; V90-T94 PolarHBondContact O-OG1 3.2Å
91R96.2Very high95.9Very high67 Ų6741.6 Ų41.625%0.25320%0.201SC..Hα-helixtrans-70.3-40.1177.4-66.3175.167-170.80.2111.6D87 Y89 I93 T94 E95 V99 E128D87-R91 WeakPolarHBondContact O-CB 3.45Å; D87-R91 WeakPolarHBondContact O-CG 3.45Å; D87-R91 PolarHBondContact O-N 3.18Å; Y89-R91 VanDerWaalsContact C-N 3.33Å; Y89-R91 PolarHBondContact O-N 3.03Å; R91-I93 PolarHBondContact O-N 2.85Å; R91-T94 PolarHBondContact O-N 3.14Å; R91-E95 IonicContact NE-OE1 3.78Å; R91-E95 WeakPolarHBondContact O-CB 3.35Å; R91-E95 WeakPolarHBondContact O-CG 3.33Å; R91-E95 PolarHBondContact O-N 2.64Å; R91-V99 HydrophobicContact CB-CB 4Å; R91-V99 HydrophobicContact CB-CG1 4.11Å; R91-V99 HydrophobicContact CB-CG2 4.09Å; R91-E128 IonicContact CZ-OE1 3.58Å; R91-E128 IonicContact CZ-OE2 2.65Å; R91-E128 IonicContact NH1-OE1 3.76Å; R91-E128 PolarHBondContact NH1-OE1 3.32Å; R91-E128 IonicContact NH1-OE2 3.94Å; R91-E128 PolarHBondContact NH1-OE2 2.73Å; R91-E128 IonicContact NH2-OE1 2.77Å; R91-E128 IonicContact NH2-OE2 3.15Å; R91-E128 PolarHBondContact NH2-OE2 2.89Å
92A95.8Very high95.8Very high2 Ų241.1 Ų41.12%0.01720%0.199CC..Hα-helixtrans-59.8-46.6177.600000112.3V52 A88 Y89 K96 R97V52-A92 HydrophobicContact CG1-CB 4.26Å; V52-A92 WeakPolarHBondContact CG1-O 3.14Å; V52-A92 HydrophobicContact CG2-CB 4.05Å; A88-A92 WeakPolarHBondContact O-CB 3.49Å; A88-A92 PolarHBondContact O-N 2.76Å; Y89-A92 PolarHBondContact O-N 2.97Å; A92-K96 VanDerWaalsContact O-CA 3.27Å; A92-K96 WeakPolarHBondContact O-CA 3.47Å; A92-K96 PolarHBondContact O-N 3.43Å; A92-R97 WeakPolarHBondContact CA-O 3.48Å; A92-R97 PolarHBondContact O-N 3.07Å
93I96.4Very high95.6Very high79 Ų7940.7 Ų40.741%0.40520%0.197SC..Hα-helixtrans-68.8-38.7177.9-60.9-55.9000111.9L49 Y89 R91L49-I93 HydrophobicContact CD2-CD1 3.91Å; Y89-I93 HydrophobicContact CD1-CG1 4.28Å; Y89-I93 HydrophobicContact CD2-CG1 4.21Å; Y89-I93 HydrophobicContact CE1-CG1 3.91Å; Y89-I93 HydrophobicContact CE2-CD1 4.14Å; Y89-I93 HydrophobicContact CE2-CG1 3.85Å; Y89-I93 HydrophobicContact CG-CG1 4.43Å; Y89-I93 WeakPolarHBondContact O-CG1 3.03Å; Y89-I93 PolarHBondContact O-N 2.9Å; R91-I93 PolarHBondContact O-N 2.85Å
94T95.4Very high95.5Very high106 Ų10640.4 Ų40.465%0.6520%0.196SC*.Hα-helixtrans-68.4-43.9-179.8-59.50000111.9V90 R91V90-T94 VanDerWaalsContact O-CB 3.23Å; V90-T94 WeakPolarHBondContact O-CB 3.43Å; V90-T94 PolarHBondContact O-N 2.86Å; V90-T94 PolarHBondContact O-OG1 3.2Å; R91-T94 PolarHBondContact O-N 3.14Å
95E92.8Very high95.2Very high70 Ų7040.5 Ų40.533%0.32720%0.197SC..Hα-helixtrans-90.9-6.9-177.1-59.7-174.2-14200113R91 R97 V99R91-E95 IonicContact NE-OE1 3.78Å; R91-E95 WeakPolarHBondContact O-CB 3.35Å; R91-E95 WeakPolarHBondContact O-CG 3.33Å; R91-E95 PolarHBondContact O-N 2.64Å; E95-R97 VanDerWaalsContact C-N 3.26Å; E95-R97 HydrophobicContact CB-CG 3.97Å; E95-R97 PolarHBondContact O-N 3.46Å; E95-R97 IonicContact OE2-CZ 3.61Å; E95-R97 VanDerWaalsContact OE2-CZ 3.29Å; E95-R97 IonicContact OE2-NE 2.78Å; E95-R97 PolarHBondContact OE2-NE 2.94Å; E95-R97 IonicContact OE2-NH2 3.54Å; E95-R97 PolarHBondContact OE2-NH2 2.9Å; E95-V99 HydrophobicContact CB-CG2 3.77Å; E95-V99 HydrophobicContact CG-CG2 4.04Å
96K93.6Very high94.8Very high165 Ų16538.8 Ų38.872%0.71719%0.192SC*.THydrogen-bonded Turntrans54.738.2-179.2-57.5179.6178.5-177.60113.6A92A92-K96 VanDerWaalsContact O-CA 3.27Å; A92-K96 WeakPolarHBondContact O-CA 3.47Å; A92-K96 PolarHBondContact O-N 3.43Å
97R92.7Very high94.2Very high32 Ų3239 Ų3912%0.12120%0.195CC..SBendtrans-159168.3179.465.8-177.1-169.381.83.3110.3A92 E95 V99 Y108A92-R97 WeakPolarHBondContact CA-O 3.48Å; A92-R97 PolarHBondContact O-N 3.07Å; E95-R97 VanDerWaalsContact C-N 3.26Å; E95-R97 HydrophobicContact CB-CG 3.97Å; E95-R97 PolarHBondContact O-N 3.46Å; E95-R97 IonicContact OE2-CZ 3.61Å; E95-R97 VanDerWaalsContact OE2-CZ 3.29Å; E95-R97 IonicContact OE2-NE 2.78Å; E95-R97 PolarHBondContact OE2-NE 2.94Å; E95-R97 IonicContact OE2-NH2 3.54Å; E95-R97 PolarHBondContact OE2-NH2 2.9Å; R97-V99 HydrophobicContact CG-CG2 3.97Å; R97-V99 PolarHBondContact O-N 2.86Å; R97-Y108 PolarHBondContact NH1-O 3Å
98V92.9Very high93.3Very high4 Ų443 Ų432%0.02421%0.205CC..  trans-74.4119170.8-176.20000109.1V52 E55 F57 I100 T105 A107V52-V98 HydrophobicContact CB-CG2 4.45Å; V52-V98 HydrophobicContact CG2-CG2 4.27Å; E55-V98 HydrophobicContact CB-CG2 4.07Å; E55-V98 WeakPolarHBondContact OE2-CB 3.2Å; E55-V98 PolarHBondContact OE2-N 3.18Å; F57-V98 HydrophobicContact CD1-CG2 4.35Å; F57-V98 HydrophobicContact CE1-CB 4.41Å; F57-V98 HydrophobicContact CE1-CG1 3.77Å; F57-V98 HydrophobicContact CE1-CG2 3.7Å; F57-V98 HydrophobicContact CZ-CG1 4.33Å; F57-V98 HydrophobicContact CZ-CG2 3.85Å; V98-I100 WeakPolarHBondContact CG1-O 3.48Å; V98-T105 HydrophobicContact CG1-CG2 4.18Å; V98-A107 HydrophobicContact CG1-CB 4.03Å
99V91.1Very high92.2Very high12 Ų1246.3 Ų46.37%0.07323%0.226CC..  trans-106.2-33.7-173.9-174.70000112.9R91 E95 R97 A107R91-V99 HydrophobicContact CB-CB 4Å; R91-V99 HydrophobicContact CB-CG1 4.11Å; R91-V99 HydrophobicContact CB-CG2 4.09Å; E95-V99 HydrophobicContact CB-CG2 3.77Å; E95-V99 HydrophobicContact CG-CG2 4.04Å; R97-V99 HydrophobicContact CG-CG2 3.97Å; R97-V99 PolarHBondContact O-N 2.86Å; V99-A107 VanDerWaalsContact C-CB 3.48Å; V99-A107 WeakPolarHBondContact O-CB 3.49Å
100I91.7Very high90.5Very high7 Ų746.9 Ų46.94%0.03623%0.231CC..SBendtrans-110.7133.7178.8-72.1177000108.1D87 A88 V98 E102 A107D87-I100 HydrophobicContact CB-CD1 4.08Å; A88-I100 HydrophobicContact CB-CB 4.35Å; A88-I100 HydrophobicContact CB-CD1 4.3Å; V98-I100 WeakPolarHBondContact CG1-O 3.48Å; I100-E102 PolarHBondContact O-N 2.9Å; I100-A107 VanDerWaalsContact C-CB 3.48Å
101T92.7Very high88.6Confident14 Ų1449.5 Ų49.59%0.08625%0.25CC..  trans-65.2123.9175.4-69.70000109.3T105 F106 A107 N275 Y276T101-T105 WeakPolarHBondContact CA-O 3.23Å; T101-F106 HydrophobicContact CG2-CD2 4.27Å; T101-F106 WeakPolarHBondContact OG1-CD2 3.45Å; T101-A107 PolarHBondContact OG1-N 2.87Å; T101-A107 VanDerWaalsContact OG1-N 3.1Å; T101-N275 HydrophobicContact CG2-CB 4.13Å; T101-Y276 HydrophobicContact CG2-CD2 4.48Å; T101-Y276 HydrophobicContact CG2-CE2 4.26Å
102E95.8Very high86.7Confident4 Ų451.9 Ų51.92%0.01928%0.275CS..  trans-94.3-175.1174.2-58.1-65.6-177.700110.3F57 D62 Q64 I100 G104 T105 T130 N132 Y276F57-E102 HydrophobicContact CD1-CG 4.21Å; F57-E102 HydrophobicContact CE1-CG 3.69Å; D62-E102 HydrophobicContact CB-CB 3.9Å; D62-E102 HydrophobicContact CB-CG 4.45Å; D62-E102 WeakPolarHBondContact OD1-CB 3.3Å; Q64-E102 PolarHBondContact NE2-OE1 3.17Å; I100-E102 PolarHBondContact O-N 2.9Å; E102-G104 PolarHBondContact O-N 3.36Å; E102-T105 PolarHBondContact N-O 3.35Å; E102-T130 WeakPolarHBondContact OE2-CB 3.43Å; E102-T130 PolarHBondContact OE2-OG1 2.69Å; E102-N132 WeakPolarHBondContact OE2-CB 3.46Å; E102-Y276 VanDerWaalsContact O-CD2 3.25Å; E102-Y276 WeakPolarHBondContact O-CD2 3.12Å
103F95Very high84.6Confident30 Ų3057 Ų5713%0.13230%0.297CS..SBendtrans-53.4-52.8-173.6-179.2-98.6000113.5H59 F61 D62 N275 Y276 M277 F280 F337 Y339H59-F103 HydrophobicContact CB-CD1 4.27Å; H59-F103 AromaticContact CE1-CD1 3.75Å; H59-F103 AromaticContact CE1-CE1 3.59Å; H59-F103 AromaticContact CG-CD1 3.7Å; H59-F103 AromaticContact ND1-CD1 3.42Å; H59-F103 WeakPolarHBondContact ND1-CD1 3.41Å; H59-F103 AromaticContact ND1-CE1 3.76Å; H59-F103 AromaticContact NE2-CE1 3.79Å; F61-F103 HydrophobicContact CB-CB 4.15Å; F61-F103 HydrophobicContact CB-CD1 4.39Å; F61-F103 HydrophobicContact CB-CG 4.35Å; F61-F103 HydrophobicContact CD2-CD1 4.3Å; F61-F103 HydrophobicContact CD2-CE1 4.48Å; D62-F103 WeakPolarHBondContact OD1-CA 3.45Å; D62-F103 VanDerWaalsContact OD1-CB 3.29Å; D62-F103 WeakPolarHBondContact OD1-CB 3.35Å; D62-F103 PolarHBondContact OD1-N 3.34Å; F103-N275 WeakPolarHBondContact O-CB 3.38Å; F103-Y276 PolarHBondContact O-N 3.22Å; F103-M277 HydrophobicContact CE1-CB 4.12Å; F103-M277 HydrophobicContact CE1-CG 4.27Å; F103-M277 HydrophobicContact CE1-SD 3.45Å; F103-M277 WeakPolarHBondContact CE1-SD 3.34Å; F103-M277 HydrophobicContact CZ-CB 4.34Å; F103-M277 HydrophobicContact CZ-SD 3.46Å; F103-M277 WeakPolarHBondContact CZ-SD 3.39Å; F103-M277 PolarHBondContact O-N 2.93Å; F103-F280 HydrophobicContact CE2-CD2 4.49Å; F103-F280 AromaticContact CE2-CE2 3.61Å; F103-F280 HydrophobicContact CE2-CE2 3.61Å; F103-F280 HydrophobicContact CE2-CZ 4.12Å; F103-F280 HydrophobicContact CZ-CD2 4.46Å; F103-F280 AromaticContact CZ-CE2 3.97Å; F103-F280 HydrophobicContact CZ-CE2 3.97Å; F103-F337 HydrophobicContact CZ-CE1 4.09Å; F103-F337 HydrophobicContact CZ-CZ 4.37Å; F103-Y339 AromaticContact CE1-CD2 3.84Å; F103-Y339 HydrophobicContact CE1-CD2 3.84Å; F103-Y339 HydrophobicContact CE2-CD2 4.29Å; F103-Y339 AromaticContact CZ-CD2 3.53Å; F103-Y339 HydrophobicContact CZ-CD2 3.53Å; F103-Y339 HydrophobicContact CZ-CE2 4.28Å; F103-Y339 HydrophobicContact CZ-CG 4.49Å
104G94.9Very high82.2Confident2 Ų259.5 Ų59.52%0.02131%0.311CS..SBendtrans-114.4-3.9178.800000114.9D62 E102 N275D62-G104 PolarHBondContact OD1-N 3.05Å; D62-G104 VanDerWaalsContact OD2-C 3.31Å; D62-G104 WeakPolarHBondContact OD2-CA 3.49Å; D62-G104 PolarHBondContact OD2-N 3.43Å; E102-G104 PolarHBondContact O-N 3.36Å; G104-N275 PolarHBondContact O-ND2 3.34Å
105T93.4Very high79.9Confident4 Ų459.9 Ų59.93%0.02531%0.308CS..  trans-110.8116.2178-67.60000111.6F57 Y58 D62 V98 T101 E102F57-T105 WeakPolarHBondContact CA-OG1 3.16Å; F57-T105 HydrophobicContact CD1-CG2 3.98Å; F57-T105 HydrophobicContact CE1-CG2 4.41Å; Y58-T105 HydrophobicContact CD2-CG2 4.08Å; Y58-T105 WeakPolarHBondContact CD2-OG1 3.33Å; Y58-T105 HydrophobicContact CE2-CG2 4.23Å; Y58-T105 PolarHBondContact N-OG1 3.39Å; D62-T105 PolarHBondContact OD2-N 2.92Å; D62-T105 VanDerWaalsContact OD2-N 3.09Å; D62-T105 PolarHBondContact OD2-OG1 2.86Å; V98-T105 HydrophobicContact CG1-CG2 4.18Å; T101-T105 WeakPolarHBondContact CA-O 3.23Å; E102-T105 PolarHBondContact N-O 3.35Å
106F90Very high77.5Confident47 Ų4765.4 Ų65.421%0.20633%0.331CS..PPolyproline II helixtrans-78.5129.9172.2178.7-110.9000111.5T101 Y108 S274T101-F106 HydrophobicContact CG2-CD2 4.27Å; T101-F106 WeakPolarHBondContact OG1-CD2 3.45Å; F106-Y108 AromaticContact CD1-CD1 3.87Å; F106-Y108 HydrophobicContact CD1-CD1 3.87Å; F106-Y108 HydrophobicContact CD1-CD2 4.28Å; F106-Y108 AromaticContact CD1-CE1 3.74Å; F106-Y108 HydrophobicContact CD1-CE1 3.74Å; F106-Y108 HydrophobicContact CD1-CE2 4.16Å; F106-Y108 HydrophobicContact CD1-CG 4.14Å; F106-Y108 AromaticContact CD1-CZ 3.9Å; F106-Y108 AromaticContact CE1-CD1 3.7Å; F106-Y108 HydrophobicContact CE1-CD1 3.7Å; F106-Y108 AromaticContact CE1-CE1 3.89Å; F106-Y108 HydrophobicContact CE1-CE1 3.89Å; F106-Y108 HydrophobicContact CE1-CG 4.17Å; F106-S274 VanDerWaalsContact CD2-N 3.27Å; F106-S274 WeakPolarHBondContact CD2-O 3.44Å
107A86.4Confident75.3Confident9 Ų959.8 Ų59.87%0.07431%0.312CS..PPolyproline II helixtrans-84.9119.417300000110.7V98 V99 I100 T101V98-A107 HydrophobicContact CG1-CB 4.03Å; V99-A107 VanDerWaalsContact C-CB 3.48Å; V99-A107 WeakPolarHBondContact O-CB 3.49Å; I100-A107 VanDerWaalsContact C-CB 3.48Å; T101-A107 PolarHBondContact OG1-N 2.87Å; T101-A107 VanDerWaalsContact OG1-N 3.1Å
108Y79.1Confident73.1Confident159 Ų15959.1 Ų59.162%0.62431%0.313SS*.PPolyproline II helixtrans-77.2145.6177-68.9-84000111.4R97 F106R97-Y108 PolarHBondContact NH1-O 3Å; F106-Y108 AromaticContact CD1-CD1 3.87Å; F106-Y108 HydrophobicContact CD1-CD1 3.87Å; F106-Y108 HydrophobicContact CD1-CD2 4.28Å; F106-Y108 AromaticContact CD1-CE1 3.74Å; F106-Y108 HydrophobicContact CD1-CE1 3.74Å; F106-Y108 HydrophobicContact CD1-CE2 4.16Å; F106-Y108 HydrophobicContact CD1-CG 4.14Å; F106-Y108 AromaticContact CD1-CZ 3.9Å; F106-Y108 AromaticContact CE1-CD1 3.7Å; F106-Y108 HydrophobicContact CE1-CD1 3.7Å; F106-Y108 AromaticContact CE1-CE1 3.89Å; F106-Y108 HydrophobicContact CE1-CE1 3.89Å; F106-Y108 HydrophobicContact CE1-CG 4.17Å
109P73.4Confident70.9Confident72 Ų7267.5 Ų67.547%0.46834%0.344SS..PPolyproline II helixtrans-57.6144.4168.5-21.932.5000110.8P111P109-P111 WeakPolarHBondContact O-CD 3.45Å; P109-P111 VanDerWaalsContact O-N 3.13Å
110D63.1Low68.3Low37 Ų3773.5 Ų73.520%0.19837%0.369CS..PPolyproline II helixtrans-50117178.8178.3-6.5000111.2C112 K113D110-C112 PolarHBondContact O-N 2.82Å; D110-C112 VanDerWaalsContact OD1-CB 3.31Å; D110-C112 WeakPolarHBondContact OD1-CB 3.19Å; D110-C112 PolarHBondContact OD1-N 3.28Å; D110-K113 HydrophobicContact CB-CB 4.34Å; D110-K113 HydrophobicContact CB-CD 3.96Å; D110-K113 HydrophobicContact CB-CG 4.03Å; D110-K113 PolarHBondContact O-N 3.05Å; D110-K113 VanDerWaalsContact OD2-CE 3.29Å; D110-K113 WeakPolarHBondContact OD2-CE 3.46Å; D110-K113 IonicContact OD2-NZ 2.98Å
111P58.3Low65.8Low118 Ų11879.8 Ų79.877%0.76640%0.397SS*.THydrogen-bonded Turntrans-66.1-19.7-176.926.5-33.8000112.9P109 K113P109-P111 WeakPolarHBondContact O-CD 3.45Å; P109-P111 VanDerWaalsContact O-N 3.13Å; P111-K113 VanDerWaalsContact C-N 3.32Å
112C56.1Low63.5Low117 Ų11782.7 Ų82.779%0.79142%0.418SS*.THydrogen-bonded Turntrans-81-11.2175.4-63.80000112.9D110D110-C112 PolarHBondContact O-N 2.82Å; D110-C112 VanDerWaalsContact OD1-CB 3.31Å; D110-C112 WeakPolarHBondContact OD1-CB 3.19Å; D110-C112 PolarHBondContact OD1-N 3.28Å
113K51.2Low61Low110 Ų11092 Ų9248%0.47845%0.454SS..SBendtrans-91.6124.6172.9-68.3179.6-171.8165.10109.6D110 P111 I115D110-K113 HydrophobicContact CB-CB 4.34Å; D110-K113 HydrophobicContact CB-CD 3.96Å; D110-K113 HydrophobicContact CB-CG 4.03Å; D110-K113 PolarHBondContact O-N 3.05Å; D110-K113 VanDerWaalsContact OD2-CE 3.29Å; D110-K113 WeakPolarHBondContact OD2-CE 3.46Å; D110-K113 IonicContact OD2-NZ 2.98Å; P111-K113 VanDerWaalsContact C-N 3.32Å; K113-I115 PolarHBondContact O-N 2.85Å
114N46.6Very low58.2Low131 Ų13197.4 Ų97.470%0.70148%0.478SS*.  trans-45.3133.2175.6-81.2-24.7000111.2F116 S117 S118N114-F116 PolarHBondContact O-N 2.86Å; N114-S117 PolarHBondContact N-OG 2.93Å; N114-S117 PolarHBondContact O-N 2.79Å; N114-S117 PolarHBondContact O-OG 2.78Å; N114-S118 PolarHBondContact O-N 2.94Å; N114-S118 PolarHBondContact O-OG 2.94Å
115I47.4Very low56Low113 Ų113104.9 Ų104.958%0.57951%0.51SS*.Hα-helixtrans-50.5-33.5-178.9-69.3167.9000112.4K113 S118 R119K113-I115 PolarHBondContact O-N 2.85Å; I115-S118 WeakPolarHBondContact CA-OG 3.28Å; I115-S118 PolarHBondContact O-OG 2.87Å; I115-R119 WeakPolarHBondContact O-CB 3.4Å; I115-R119 WeakPolarHBondContact O-CG 3.43Å; I115-R119 PolarHBondContact O-N 2.85Å; I115-R119 VanDerWaalsContact O-N 3.14Å
116F42.5Very low54.4Low187 Ų187107.2 Ų107.282%0.8254%0.535SS*.Hα-helixtrans-71.2-38.8175.4-83.3-84.8000113.3N114 F120N114-F116 PolarHBondContact O-N 2.86Å; F116-F120 WeakPolarHBondContact O-CB 3.35Å; F116-F120 PolarHBondContact O-N 2.75Å; F116-F120 VanDerWaalsContact O-N 3.15Å
117S46.9Very low53.5Low46 Ų46108.3 Ų108.332%0.32255%0.545SS..Hα-helixtrans-75.5-38177.5610000111.6N114 F121N114-S117 PolarHBondContact N-OG 2.93Å; N114-S117 PolarHBondContact O-N 2.79Å; N114-S117 PolarHBondContact O-OG 2.78Å; S117-F121 VanDerWaalsContact O-CB 3.32Å; S117-F121 WeakPolarHBondContact O-CB 3.4Å; S117-F121 WeakPolarHBondContact O-CD2 3.3Å; S117-F121 PolarHBondContact O-N 3.47Å
118S46.1Very low53.4Low18 Ų18112 Ų11213%0.12656%0.56CS.*Hα-helixtrans-68.6-41.8178.358.30000112.8N114 I115 S122N114-S118 PolarHBondContact O-N 2.94Å; N114-S118 PolarHBondContact O-OG 2.94Å; I115-S118 WeakPolarHBondContact CA-OG 3.28Å; I115-S118 PolarHBondContact O-OG 2.87Å; S118-S122 VanDerWaalsContact O-CB 3.26Å; S118-S122 WeakPolarHBondContact O-CB 3.39Å; S118-S122 PolarHBondContact O-N 2.77Å; S118-S122 VanDerWaalsContact O-N 3.08Å; S118-S122 PolarHBondContact O-OG 2.73Å
119R46Very low53.9Low181 Ų181106 Ų10668%0.68354%0.541SS*.Hα-helixtrans-70.3-41.5175.6-77.4-174.6165.3149.7-1.9113.3I115 Y123I115-R119 WeakPolarHBondContact O-CB 3.4Å; I115-R119 WeakPolarHBondContact O-CG 3.43Å; I115-R119 PolarHBondContact O-N 2.85Å; I115-R119 VanDerWaalsContact O-N 3.14Å; R119-Y123 PolarHBondContact O-N 3.14Å
120F37.5Very low55Low138 Ų138103 Ų10361%0.60552%0.521SS*.Hα-helixtrans-68.1-46.3-179.7-154.9-97.5000110.7F116 S122 Y123 F124F116-F120 WeakPolarHBondContact O-CB 3.35Å; F116-F120 PolarHBondContact O-N 2.75Å; F116-F120 VanDerWaalsContact O-N 3.15Å; F120-S122 PolarHBondContact O-N 3.3Å; F120-Y123 WeakPolarHBondContact O-CB 3.37Å; F120-Y123 PolarHBondContact O-N 3.38Å; F120-F124 HydrophobicContact CD1-CD2 4.1Å; F120-F124 AromaticContact CD1-CE2 3.68Å; F120-F124 HydrophobicContact CD1-CE2 3.68Å; F120-F124 HydrophobicContact CE1-CD2 4.22Å; F120-F124 AromaticContact CE1-CE2 3.4Å; F120-F124 HydrophobicContact CE1-CE2 3.4Å; F120-F124 HydrophobicContact CE1-CZ 4.19Å; F120-F124 HydrophobicContact CG-CE2 4.36Å; F120-F124 AromaticContact CZ-CE2 3.86Å; F120-F124 HydrophobicContact CZ-CE2 3.86Å; F120-F124 HydrophobicContact CZ-CZ 4.38Å; F120-F124 WeakPolarHBondContact O-CD2 3.4Å
121F38.6Very low56.6Low139 Ų139101.3 Ų101.361%0.6151%0.512SS*.Hα-helixtrans-67.9-34177.4-87.8-84.9000113.8S117 Y123 F124 K125S117-F121 VanDerWaalsContact O-CB 3.32Å; S117-F121 WeakPolarHBondContact O-CB 3.4Å; S117-F121 WeakPolarHBondContact O-CD2 3.3Å; S117-F121 PolarHBondContact O-N 3.47Å; F121-Y123 VanDerWaalsContact C-N 3.28Å; F121-Y123 PolarHBondContact O-N 3.01Å; F121-F124 PolarHBondContact O-N 2.76Å; F121-K125 PolarHBondContact O-N 2.9Å
122S44.7Very low58.6Low75 Ų7595.8 Ų95.852%0.52448%0.476SS..Hα-helixtrans-65.9-32.7175.2-58.10000112S118 F120 F124 K125S118-S122 VanDerWaalsContact O-CB 3.26Å; S118-S122 WeakPolarHBondContact O-CB 3.39Å; S118-S122 PolarHBondContact O-N 2.77Å; S118-S122 VanDerWaalsContact O-N 3.08Å; S118-S122 PolarHBondContact O-OG 2.73Å; F120-S122 PolarHBondContact O-N 3.3Å; S122-F124 PolarHBondContact O-N 3.41Å; S122-K125 PolarHBondContact O-N 3Å
123Y42.8Very low60.6Low198 Ų19890.2 Ų90.278%0.77644%0.438SS*.Hα-helixtrans-63.8-28.8175.1-160.9-91.6000112.9R119 F120 F121R119-Y123 PolarHBondContact O-N 3.14Å; F120-Y123 WeakPolarHBondContact O-CB 3.37Å; F120-Y123 PolarHBondContact O-N 3.38Å; F121-Y123 VanDerWaalsContact C-N 3.28Å; F121-Y123 PolarHBondContact O-N 3.01Å
124F36.9Very low62.8Low145 Ų14585 Ų8564%0.63642%0.416SS*.Hα-helixtrans-93.8-13.3-179.4-73.2-77.1000114.7F120 F121 S122F120-F124 HydrophobicContact CD1-CD2 4.1Å; F120-F124 AromaticContact CD1-CE2 3.68Å; F120-F124 HydrophobicContact CD1-CE2 3.68Å; F120-F124 HydrophobicContact CE1-CD2 4.22Å; F120-F124 AromaticContact CE1-CE2 3.4Å; F120-F124 HydrophobicContact CE1-CE2 3.4Å; F120-F124 HydrophobicContact CE1-CZ 4.19Å; F120-F124 HydrophobicContact CG-CE2 4.36Å; F120-F124 AromaticContact CZ-CE2 3.86Å; F120-F124 HydrophobicContact CZ-CE2 3.86Å; F120-F124 HydrophobicContact CZ-CZ 4.38Å; F120-F124 WeakPolarHBondContact O-CD2 3.4Å; F121-F124 PolarHBondContact O-N 2.76Å; S122-F124 PolarHBondContact O-N 3.41Å
125K49.5Very low65.3Low159 Ų15979.3 Ų79.369%0.69139%0.385SS*.Hα-helixtrans-98.7-2.3-172.5-92.3-167.3169.7-165.60116.4F121 S122F121-K125 PolarHBondContact O-N 2.9Å; S122-K125 PolarHBondContact O-N 3Å
126G59.3Low67.7Low53 Ų5374.8 Ų74.855%0.54636%0.362SS..  trans69.3170-176.600000112.5E128G126-E128 PolarHBondContact O-N 2.95Å
127V71.1Confident70.4Confident70 Ų7066 Ų6642%0.42432%0.324SS..  trans-76.1122.8-179.1171.70000110.1V129 W269V127-V129 HydrophobicContact CG1-CG2 4.29Å; V127-V129 PolarHBondContact O-N 2.89Å; V127-W269 HydrophobicContact CG1-CG 4.3Å; V127-W269 HydrophobicContact CG2-CB 4.25Å; V127-W269 VanDerWaalsContact CG2-CD1 3.46Å; V127-W269 HydrophobicContact CG2-CG 4Å
128E83.4Confident72.9Confident86 Ų8664.2 Ų64.240%0.40231%0.31SS..  trans-81.7100.1173.4-61.4-171.8137.700109.6R91 G126R91-E128 IonicContact CZ-OE1 3.58Å; R91-E128 IonicContact CZ-OE2 2.65Å; R91-E128 IonicContact NH1-OE1 3.76Å; R91-E128 PolarHBondContact NH1-OE1 3.32Å; R91-E128 IonicContact NH1-OE2 3.94Å; R91-E128 PolarHBondContact NH1-OE2 2.73Å; R91-E128 IonicContact NH2-OE1 2.77Å; R91-E128 IonicContact NH2-OE2 3.15Å; R91-E128 PolarHBondContact NH2-OE2 2.89Å; G126-E128 PolarHBondContact O-N 2.95Å
129V91.2Very high75.3Confident34 Ų3465 Ų6521%0.20632%0.315CS..  trans-76.7143.4174.6178.90000109.8V127 T150 Y152V127-V129 HydrophobicContact CG1-CG2 4.29Å; V127-V129 PolarHBondContact O-N 2.89Å; V129-T150 HydrophobicContact CG1-CG2 3.68Å; V129-Y152 HydrophobicContact CB-CD2 4.45Å; V129-Y152 HydrophobicContact CB-CE2 4Å; V129-Y152 WeakPolarHBondContact O-CE2 3.18Å
130T95.5Very high77.8Confident9 Ų956.4 Ų56.46%0.05528%0.282CS..  trans-67.3140.9-178.6-174.70000112.1E102 N132 T150 Y276E102-T130 WeakPolarHBondContact OE2-CB 3.43Å; E102-T130 PolarHBondContact OE2-OG1 2.69Å; T130-N132 WeakPolarHBondContact OG1-CB 3.25Å; T130-N132 PolarHBondContact OG1-N 2.73Å; T130-N132 VanDerWaalsContact OG1-N 3.11Å; T130-T150 HydrophobicContact CG2-CG2 3.79Å; T130-T150 WeakPolarHBondContact O-CG2 3.47Å; T130-T150 PolarHBondContact O-OG1 3.26Å; T130-Y276 HydrophobicContact CG2-CE2 4.15Å; T130-Y276 PolarHBondContact N-OH 3.27Å
131D97.6Very high80.6Confident1 Ų151 Ų511%0.00527%0.266CS..  trans-114.417.4169.867.7-15.5000112T86 D87 A88 C133 Y152 K166T86-D131 WeakPolarHBondContact CB-OD1 3.44Å; T86-D131 WeakPolarHBondContact CG2-O 3.48Å; D87-D131 VanDerWaalsContact CB-OD2 3.29Å; D87-D131 WeakPolarHBondContact CB-OD2 3.48Å; D87-D131 PolarHBondContact N-OD1 2.93Å; D87-D131 PolarHBondContact N-OD2 3.12Å; A88-D131 PolarHBondContact N-OD1 2.97Å; D131-C133 VanDerWaalsContact C-N 3.33Å; D131-C133 PolarHBondContact O-N 3.32Å; D131-C133 PolarHBondContact O-SG 3.01Å; D131-Y152 HydrophobicContact CB-CD2 3.99Å; D131-Y152 HydrophobicContact CB-CG 4.06Å; D131-K166 HydrophobicContact CB-CD 4.42Å; D131-K166 WeakPolarHBondContact OD2-CD 3.1Å; D131-K166 WeakPolarHBondContact OD2-CE 3.29Å; D131-K166 IonicContact OD2-NZ 3.75Å; D131-K166 PolarHBondContact OD2-NZ 3Å
132N98.5Very high83.2Confident1 Ų151.7 Ų51.71%0.00527%0.271CS..  trans-65.188.5175.1-175.114.8000110.8D62 G63 A65 A88 E102 T130 L134 T148D62-N132 PolarHBondContact O-ND2 2.78Å; G63-N132 PolarHBondContact O-ND2 2.94Å; A65-N132 VanDerWaalsContact CB-OD1 3.29Å; A65-N132 WeakPolarHBondContact CB-OD1 3.35Å; A65-N132 PolarHBondContact N-OD1 2.81Å; A88-N132 HydrophobicContact CB-CB 4.24Å; E102-N132 WeakPolarHBondContact OE2-CB 3.46Å; T130-N132 WeakPolarHBondContact OG1-CB 3.25Å; T130-N132 PolarHBondContact OG1-N 2.73Å; T130-N132 VanDerWaalsContact OG1-N 3.11Å; N132-L134 VanDerWaalsContact C-N 3.27Å; N132-L134 WeakPolarHBondContact O-CD2 3.41Å; N132-L134 PolarHBondContact O-N 2.78Å; N132-T148 VanDerWaalsContact O-CB 3.22Å; N132-T148 WeakPolarHBondContact O-CB 3.38Å
133C98.4Very high85.7Confident0 Ų050.3 Ų50.30%026%0.258CS..  trans-8259-172.2-700000113.1D131 A146 V147 T154D131-C133 VanDerWaalsContact C-N 3.33Å; D131-C133 PolarHBondContact O-N 3.32Å; D131-C133 PolarHBondContact O-SG 3.01Å; C133-A146 HydrophobicContact CB-CB 3.84Å; C133-A146 PolarHBondContact SG-O 3.26Å; C133-A146 VanDerWaalsContact SG-O 3.37Å; C133-V147 CarbonylContact C-O 3.52Å; C133-T154 PolarHBondContact SG-OG1 3.34Å
134L98.6Very high88.4Confident2 Ų242.4 Ų42.41%0.0123%0.227CC..  trans-88.6-3.8-172.977.9166.4000115.8L45 G46 P47 G63 A65 N132 F526L45-L134 CarbonylContact C-O 3.51Å; L45-L134 WeakPolarHBondContact CB-O 3.31Å; G46-L134 WeakPolarHBondContact CA-O 3.46Å; G46-L134 PolarHBondContact N-O 3.3Å; P47-L134 HydrophobicContact CB-CD1 4.12Å; G63-L134 WeakPolarHBondContact O-CD1 3.31Å; A65-L134 HydrophobicContact CB-CB 3.77Å; N132-L134 VanDerWaalsContact C-N 3.27Å; N132-L134 WeakPolarHBondContact O-CD2 3.41Å; N132-L134 PolarHBondContact O-N 2.78Å; L134-F526 HydrophobicContact CD1-CE2 3.89Å; L134-F526 HydrophobicContact CG-CE2 4.15Å
135V98.7Very high91.3Very high11 Ų1135.6 Ų35.67%0.06720%0.198CC..SBendtrans-91.3-54.5-164.7-1750000112.5V147 A180 H527V135-V147 WeakPolarHBondContact CB-O 3.32Å; V135-V147 PolarHBondContact N-O 2.88Å; V135-A180 HydrophobicContact CB-CB 3.78Å; V135-A180 HydrophobicContact CG1-CB 3.36Å; V135-H527 WeakPolarHBondContact O-CB 3.32Å; V135-H527 PolarHBondContact O-N 3.42Å; V135-H527 VanDerWaalsContact O-N 3.16Å
136N98.8Very high93.7Very high18 Ų1828 Ų2810%0.09617%0.165CC..EExtended strand (participates in β ladder)trans-151.2163.4-173.1-161.97.9000112.6L45 A146 V147 A180 H527 G528L45-N136 WeakPolarHBondContact CD1-O 3.4Å; N136-A146 CarbonylContact O-C 3.58Å; N136-A146 WeakPolarHBondContact O-CA 3.44Å; N136-V147 HydrophobicContact CB-CG2 3.82Å; N136-V147 PolarHBondContact N-O 2.99Å; N136-V147 WeakPolarHBondContact O-CG2 3.39Å; N136-V147 PolarHBondContact O-N 3.33Å; N136-A180 HydrophobicContact CB-CB 4.15Å; N136-A180 WeakPolarHBondContact CB-O 3.14Å; N136-A180 PolarHBondContact ND2-O 2.68Å; N136-H527 HydrophobicContact CB-CB 3.8Å; N136-H527 VanDerWaalsContact CG-CB 3.44Å; N136-H527 WeakPolarHBondContact OD1-CB 3.14Å; N136-G528 PolarHBondContact OD1-N 3.08Å
137V98.6Very high95.6Very high1 Ų125.5 Ų25.51%0.00614%0.139CC..EExtended strand (participates in β ladder)trans-130.7133.3169.353.70000109.9L43 L45 M67 F144 Y145 V156 M529L43-V137 HydrophobicContact CB-CG1 3.96Å; L45-V137 HydrophobicContact CD1-CB 3.65Å; L45-V137 HydrophobicContact CD1-CG1 4.07Å; M67-V137 HydrophobicContact CE-CG1 4.3Å; M67-V137 HydrophobicContact CE-CG2 4.19Å; V137-F144 HydrophobicContact CG2-CB 4.29Å; V137-Y145 VanDerWaalsContact CA-O 3.27Å; V137-Y145 WeakPolarHBondContact CA-O 3.45Å; V137-V156 HydrophobicContact CG2-CG2 4.28Å; V137-M529 HydrophobicContact CG1-CG 4.35Å
138Y98.1Very high96.9Very high9 Ų923 Ų234%0.03512%0.123CC..EExtended strand (participates in β ladder)trans-146.6159.1178.764.5-100.7000112.3I140 Y145 V147 P182 I184 V190Y138-I140 HydrophobicContact CD2-CG1 4.04Å; Y138-I140 HydrophobicContact CE2-CD1 3.74Å; Y138-I140 HydrophobicContact CE2-CG1 3.59Å; Y138-Y145 PolarHBondContact N-O 3.12Å; Y138-Y145 VanDerWaalsContact N-O 3.13Å; Y138-Y145 PolarHBondContact O-N 3.42Å; Y138-V147 HydrophobicContact CD1-CG1 4.19Å; Y138-V147 HydrophobicContact CD1-CG2 4.06Å; Y138-V147 HydrophobicContact CE1-CB 4.13Å; Y138-V147 HydrophobicContact CE1-CG1 3.38Å; Y138-V147 HydrophobicContact CE1-CG2 3.7Å; Y138-P182 HydrophobicContact CD1-CG 3.52Å; Y138-P182 HydrophobicContact CD2-CG 3.76Å; Y138-P182 HydrophobicContact CE1-CG 3.55Å; Y138-P182 HydrophobicContact CE2-CG 3.81Å; Y138-P182 HydrophobicContact CG-CG 3.63Å; Y138-I184 HydrophobicContact CD2-CD1 4.28Å; Y138-V190 HydrophobicContact CE2-CG1 4.33Å
139P97.9Very high97.5Very high34 Ų3421.3 Ų21.322%0.22112%0.115CC..EExtended strand (participates in β ladder)trans-81.7143.6179.632-33.9000112.5D143 F144 I184 M529P139-D143 CarbonylContact C-O 3.55Å; P139-D143 VanDerWaalsContact CA-O 3.27Å; P139-D143 WeakPolarHBondContact CA-O 3.48Å; P139-F144 HydrophobicContact CB-CD1 4.12Å; P139-F144 HydrophobicContact CB-CE1 3.96Å; P139-I184 HydrophobicContact CG-CD1 3.89Å; P139-M529 HydrophobicContact CG-CE 4.29Å
140I98Very high97.7Very high1 Ų120.4 Ų20.41%0.00511%0.11CC..EExtended strand (participates in β ladder)trans-129.4108.1162.5-56.7174.6000106.6Y138 E142 D143 Y145 I153 V190 I210 P220 I221Y138-I140 HydrophobicContact CD2-CG1 4.04Å; Y138-I140 HydrophobicContact CE2-CD1 3.74Å; Y138-I140 HydrophobicContact CE2-CG1 3.59Å; I140-E142 PolarHBondContact O-N 3.32Å; I140-D143 PolarHBondContact N-O 3.33Å; I140-D143 PolarHBondContact O-N 3.01Å; I140-Y145 HydrophobicContact CB-CD2 3.97Å; I140-Y145 HydrophobicContact CB-CE2 3.82Å; I140-Y145 HydrophobicContact CD1-CD2 3.75Å; I140-Y145 HydrophobicContact CD1-CE2 4.05Å; I140-Y145 HydrophobicContact CD1-CG 4.24Å; I140-Y145 HydrophobicContact CG1-CD2 3.88Å; I140-Y145 HydrophobicContact CG1-CE2 4.2Å; I140-I153 HydrophobicContact CD1-CD1 4.24Å; I140-V190 HydrophobicContact CG1-CG2 4.36Å; I140-I210 HydrophobicContact CD1-CD1 3.95Å; I140-I210 HydrophobicContact CG2-CG2 3.76Å; I140-P220 HydrophobicContact CG2-CB 4.18Å; I140-I221 HydrophobicContact CD1-CD1 4.01Å; I140-I221 HydrophobicContact CD1-CG1 4.16Å; I140-I221 HydrophobicContact CG2-CG1 3.97Å
141G95.5Very high97.8Very high25 Ų2520.5 Ų20.526%0.25811%0.11SC..THydrogen-bonded Turntrans62.9-126-170.700000111.9T213G141-T213 WeakPolarHBondContact CA-OG1 3.21Å
142E94.8Very high97.8Very high153 Ų15322.7 Ų22.772%0.71512%0.119SC*.THydrogen-bonded Turntrans-88.5-7.2177.6-62.8-179.2-176.300113I140I140-E142 PolarHBondContact O-N 3.32Å
143D97.3Very high97.8Very high47 Ų4722.7 Ų22.725%0.25112%0.118SC..EExtended strand (participates in β ladder)trans-102.7160.4-173.3-68.7-47.3000112.2P139 I140 Y145 K155P139-D143 CarbonylContact C-O 3.55Å; P139-D143 VanDerWaalsContact CA-O 3.27Å; P139-D143 WeakPolarHBondContact CA-O 3.48Å; I140-D143 PolarHBondContact N-O 3.33Å; I140-D143 PolarHBondContact O-N 3.01Å; D143-Y145 HydrophobicContact CB-CD2 4.49Å; D143-Y145 HydrophobicContact CB-CE2 3.59Å; D143-K155 HydrophobicContact CB-CD 4.43Å; D143-K155 WeakPolarHBondContact OD1-CE 3.37Å; D143-K155 IonicContact OD1-NZ 2.68Å; D143-K155 PolarHBondContact OD1-NZ 2.84Å; D143-K155 WeakPolarHBondContact OD2-CE 3.48Å; D143-K155 IonicContact OD2-NZ 3.76Å; D143-K155 PolarHBondContact OD2-NZ 3.4Å
144F98.4Very high97.8Very high32 Ų3222.8 Ų22.814%0.1412%0.119CC..EExtended strand (participates in β ladder)trans-124.3139.8180-64.1-96.3000110.8V137 P139 K155 V156 T158 M529 K531V137-F144 HydrophobicContact CG2-CB 4.29Å; P139-F144 HydrophobicContact CB-CD1 4.12Å; P139-F144 HydrophobicContact CB-CE1 3.96Å; F144-K155 WeakPolarHBondContact O-CA 3.19Å; F144-V156 HydrophobicContact CB-CG2 4.24Å; F144-V156 PolarHBondContact O-N 3.49Å; F144-T158 HydrophobicContact CB-CG2 3.49Å; F144-T158 VanDerWaalsContact CB-CG2 3.49Å; F144-T158 HydrophobicContact CD1-CG2 3.72Å; F144-T158 HydrophobicContact CD2-CG2 3.65Å; F144-T158 HydrophobicContact CE1-CG2 4.34Å; F144-T158 HydrophobicContact CE2-CG2 4.3Å; F144-T158 HydrophobicContact CG-CG2 3.32Å; F144-M529 HydrophobicContact CD1-CE 4.45Å; F144-M529 HydrophobicContact CD1-SD 3.76Å; F144-M529 HydrophobicContact CE1-CE 3.78Å; F144-M529 HydrophobicContact CE1-SD 3.69Å; F144-K531 HydrophobicContact CE1-CD 4.42Å; F144-K531 HydrophobicContact CE2-CD 4.45Å; F144-K531 HydrophobicContact CZ-CD 3.91Å; F144-K531 HydrophobicContact CZ-CG 4.2Å
145Y98.8Very high97.8Very high2 Ų224.7 Ų24.71%0.00813%0.127CC..EExtended strand (participates in β ladder)trans-128.7122.1-174.8-65.2-96.7000110.3V137 Y138 I140 D143 I153 T154 K155 V167 I221V137-Y145 VanDerWaalsContact CA-O 3.27Å; V137-Y145 WeakPolarHBondContact CA-O 3.45Å; Y138-Y145 PolarHBondContact N-O 3.12Å; Y138-Y145 VanDerWaalsContact N-O 3.13Å; Y138-Y145 PolarHBondContact O-N 3.42Å; I140-Y145 HydrophobicContact CB-CD2 3.97Å; I140-Y145 HydrophobicContact CB-CE2 3.82Å; I140-Y145 HydrophobicContact CD1-CD2 3.75Å; I140-Y145 HydrophobicContact CD1-CE2 4.05Å; I140-Y145 HydrophobicContact CD1-CG 4.24Å; I140-Y145 HydrophobicContact CG1-CD2 3.88Å; I140-Y145 HydrophobicContact CG1-CE2 4.2Å; D143-Y145 HydrophobicContact CB-CD2 4.49Å; D143-Y145 HydrophobicContact CB-CE2 3.59Å; Y145-I153 HydrophobicContact CD1-CB 4.41Å; Y145-I153 HydrophobicContact CD1-CD1 3.56Å; Y145-I153 HydrophobicContact CD1-CG1 3.78Å; Y145-I153 HydrophobicContact CE1-CD1 4.09Å; Y145-I153 HydrophobicContact CE1-CG1 4.41Å; Y145-I153 HydrophobicContact CG-CD1 3.97Å; Y145-I153 HydrophobicContact CG-CG1 4.49Å; Y145-T154 CarbonylContact C-O 3.59Å; Y145-T154 WeakPolarHBondContact CA-O 3.45Å; Y145-K155 HydrophobicContact CD1-CB 3.9Å; Y145-K155 HydrophobicContact CE1-CB 3.62Å; Y145-K155 HydrophobicContact CE1-CD 4.39Å; Y145-K155 HydrophobicContact CE1-CG 4.05Å; Y145-V167 HydrophobicContact CE1-CG2 3.95Å; Y145-I221 HydrophobicContact CE1-CD1 3.79Å; Y145-I221 HydrophobicContact CE2-CD1 4.13Å; Y145-I221 WeakPolarHBondContact OH-CD1 3.14Å
146A98.8Very high97.8Very high0 Ų024.3 Ų24.30%013%0.125CC..EExtended strand (participates in β ladder)trans-75.1140.3163.100000108.9L45 C133 N136 T154 V156L45-A146 HydrophobicContact CD1-CB 3.67Å; L45-A146 HydrophobicContact CD2-CB 4.45Å; C133-A146 HydrophobicContact CB-CB 3.84Å; C133-A146 PolarHBondContact SG-O 3.26Å; C133-A146 VanDerWaalsContact SG-O 3.37Å; N136-A146 CarbonylContact O-C 3.58Å; N136-A146 WeakPolarHBondContact O-CA 3.44Å; A146-T154 PolarHBondContact N-O 3.22Å; A146-T154 PolarHBondContact O-N 3.42Å; A146-V156 HydrophobicContact CB-CG1 4.13Å
147V98.7Very high97.8Very high0 Ų025.8 Ų25.80%013%0.133CC..EExtended strand (participates in β ladder)trans-137.4156.8-172.8-590000113.3C133 V135 N136 Y138 I153 A180C133-V147 CarbonylContact C-O 3.52Å; V135-V147 WeakPolarHBondContact CB-O 3.32Å; V135-V147 PolarHBondContact N-O 2.88Å; N136-V147 HydrophobicContact CB-CG2 3.82Å; N136-V147 PolarHBondContact N-O 2.99Å; N136-V147 WeakPolarHBondContact O-CG2 3.39Å; N136-V147 PolarHBondContact O-N 3.33Å; Y138-V147 HydrophobicContact CD1-CG1 4.19Å; Y138-V147 HydrophobicContact CD1-CG2 4.06Å; Y138-V147 HydrophobicContact CE1-CB 4.13Å; Y138-V147 HydrophobicContact CE1-CG1 3.38Å; Y138-V147 HydrophobicContact CE1-CG2 3.7Å; V147-I153 HydrophobicContact CB-CG2 4.24Å; V147-I153 HydrophobicContact CG1-CB 3.9Å; V147-I153 HydrophobicContact CG1-CG2 3.47Å; V147-I153 VanDerWaalsContact CG1-CG2 3.47Å; V147-A180 HydrophobicContact CG2-CB 3.79Å
148T98.3Very high97.7Very high16 Ų1626 Ų2610%0.09813%0.134CC..  trans-124.3-155.4159.8-173.20000107.5N132 T150N132-T148 VanDerWaalsContact O-CB 3.22Å; N132-T148 WeakPolarHBondContact O-CB 3.38Å; T148-T150 HydrophobicContact CG2-CG2 4.07Å
149E97.5Very high97.6Very high51 Ų5130 Ų3024%0.23816%0.157CC..SBendtrans-105.522-177.5-56.5-163.8133.200114.3I178 A180 Y240 H242E149-I178 CarbonylContact C-O 3.57Å; E149-I178 VanDerWaalsContact CA-O 3.23Å; E149-I178 WeakPolarHBondContact CA-O 3.14Å; E149-A180 HydrophobicContact CG-CB 4.4Å; E149-Y240 WeakPolarHBondContact OE2-CE2 3.45Å; E149-Y240 VanDerWaalsContact OE2-CZ 3.24Å; E149-Y240 PolarHBondContact OE2-OH 3.42Å; E149-H242 IonicContact OE1-CE1 3.67Å; E149-H242 IonicContact OE1-CG 3.59Å; E149-H242 IonicContact OE1-ND1 2.8Å; E149-H242 PolarHBondContact OE1-ND1 3.25Å; E149-H242 VanDerWaalsContact OE1-ND1 3.15Å
150T95.9Very high97.6Very high15 Ų1530.9 Ų30.99%0.09216%0.161CC..SBendtrans-100.1-171.1176.171.10000110.9V129 T130 T148 Y152 G177 I178V129-T150 HydrophobicContact CG1-CG2 3.68Å; T130-T150 HydrophobicContact CG2-CG2 3.79Å; T130-T150 WeakPolarHBondContact O-CG2 3.47Å; T130-T150 PolarHBondContact O-OG1 3.26Å; T148-T150 HydrophobicContact CG2-CG2 4.07Å; T150-Y152 VanDerWaalsContact C-N 3.28Å; T150-Y152 PolarHBondContact OG1-N 3.01Å; T150-G177 WeakPolarHBondContact O-CA 3.37Å; T150-I178 PolarHBondContact O-N 3.49Å
151N96.1Very high97.6Very high11 Ų1131 Ų316%0.05916%0.162CC..SBendtrans-77.4-13.2172.159.8-57.7000113.4D168 M169 C170N151-D168 PolarHBondContact ND2-OD1 2.84Å; N151-D168 PolarHBondContact ND2-OD2 3.02Å; N151-M169 WeakPolarHBondContact O-CB 3.05Å; N151-M169 PolarHBondContact O-N 2.78Å; N151-C170 WeakPolarHBondContact CB-SG 3.31Å
152Y98.1Very high97.8Very high48 Ų4834 Ų3419%0.18817%0.169CC..EExtended strand (participates in β ladder)trans-92.6127.1-178-64.2-53.6000111.8V129 D131 T150 K166 V167 D168V129-Y152 HydrophobicContact CB-CD2 4.45Å; V129-Y152 HydrophobicContact CB-CE2 4Å; V129-Y152 WeakPolarHBondContact O-CE2 3.18Å; D131-Y152 HydrophobicContact CB-CD2 3.99Å; D131-Y152 HydrophobicContact CB-CG 4.06Å; T150-Y152 VanDerWaalsContact C-N 3.28Å; T150-Y152 PolarHBondContact OG1-N 3.01Å; Y152-K166 HydrophobicContact CD1-CD 4.34Å; Y152-K166 HydrophobicContact CD1-CG 4.24Å; Y152-K166 VanDerWaalsContact CG-CE 3.41Å; Y152-V167 WeakPolarHBondContact CA-O 3.45Å; Y152-D168 HydrophobicContact CD1-CB 3.91Å; Y152-D168 HydrophobicContact CE1-CB 3.67Å; Y152-D168 WeakPolarHBondContact CE1-OD2 3.29Å
153I98.4Very high98Very high0 Ų028.5 Ų28.50%015%0.146CC..EExtended strand (participates in β ladder)trans-121.7149.9169.366.2177.6000109.8I140 Y145 V147 V167 M169 I178 I221I140-I153 HydrophobicContact CD1-CD1 4.24Å; Y145-I153 HydrophobicContact CD1-CB 4.41Å; Y145-I153 HydrophobicContact CD1-CD1 3.56Å; Y145-I153 HydrophobicContact CD1-CG1 3.78Å; Y145-I153 HydrophobicContact CE1-CD1 4.09Å; Y145-I153 HydrophobicContact CE1-CG1 4.41Å; Y145-I153 HydrophobicContact CG-CD1 3.97Å; Y145-I153 HydrophobicContact CG-CG1 4.49Å; V147-I153 HydrophobicContact CB-CG2 4.24Å; V147-I153 HydrophobicContact CG1-CB 3.9Å; V147-I153 HydrophobicContact CG1-CG2 3.47Å; V147-I153 VanDerWaalsContact CG1-CG2 3.47Å; I153-V167 HydrophobicContact CD1-CB 4.42Å; I153-V167 HydrophobicContact CD1-CG1 4.48Å; I153-V167 HydrophobicContact CG1-CB 3.77Å; I153-V167 HydrophobicContact CG1-CG1 4.24Å; I153-V167 PolarHBondContact N-O 3.15Å; I153-V167 PolarHBondContact O-N 2.95Å; I153-M169 HydrophobicContact CD1-CG 4.21Å; I153-M169 HydrophobicContact CD1-SD 3.65Å; I153-M169 HydrophobicContact CG1-CG 4.39Å; I153-M169 HydrophobicContact CG1-SD 4.32Å; I153-M169 HydrophobicContact CG2-CG 4.42Å; I153-I178 HydrophobicContact CG2-CD1 3.76Å; I153-I221 HydrophobicContact CD1-CD1 4.19Å
154T98.8Very high98Very high2 Ų230.8 Ų30.81%0.01216%0.158CC..EExtended strand (participates in β ladder)trans-117.7112.6-174.9-58.70000110.9V84 C133 Y145 A146 V156 T163V84-T154 HydrophobicContact CG1-CG2 3.65Å; C133-T154 PolarHBondContact SG-OG1 3.34Å; Y145-T154 CarbonylContact C-O 3.59Å; Y145-T154 WeakPolarHBondContact CA-O 3.45Å; A146-T154 PolarHBondContact N-O 3.22Å; A146-T154 PolarHBondContact O-N 3.42Å; T154-V156 HydrophobicContact CG2-CG1 4.36Å; T154-V156 PolarHBondContact O-N 3.13Å; T154-T163 HydrophobicContact CG2-CG2 3.48Å; T154-T163 VanDerWaalsContact CG2-CG2 3.48Å
155K98.7Very high98Very high42 Ų4234.8 Ų34.818%0.18318%0.175CC..EExtended strand (participates in β ladder)trans-64.3130.5172.7-170.9175.6170.5162.10109.9D143 F144 Y145 L164 K165D143-K155 HydrophobicContact CB-CD 4.43Å; D143-K155 WeakPolarHBondContact OD1-CE 3.37Å; D143-K155 IonicContact OD1-NZ 2.68Å; D143-K155 PolarHBondContact OD1-NZ 2.84Å; D143-K155 WeakPolarHBondContact OD2-CE 3.48Å; D143-K155 IonicContact OD2-NZ 3.76Å; D143-K155 PolarHBondContact OD2-NZ 3.4Å; F144-K155 WeakPolarHBondContact O-CA 3.19Å; Y145-K155 HydrophobicContact CD1-CB 3.9Å; Y145-K155 HydrophobicContact CE1-CB 3.62Å; Y145-K155 HydrophobicContact CE1-CD 4.39Å; Y145-K155 HydrophobicContact CE1-CG 4.05Å; K155-L164 HydrophobicContact CB-CB 4.31Å; K155-L164 HydrophobicContact CD-CB 4.49Å; K155-L164 HydrophobicContact CD-CD1 4.42Å; K155-L164 HydrophobicContact CG-CB 4.19Å; K155-L164 HydrophobicContact CG-CD1 4.16Å; K155-L164 WeakPolarHBondContact O-CB 3.48Å; K155-L164 PolarHBondContact O-N 3.42Å; K155-K165 HydrophobicContact CB-CB 4.18Å; K155-K165 WeakPolarHBondContact CB-O 3.18Å; K155-K165 PolarHBondContact N-O 3.35Å; K155-K165 PolarHBondContact O-N 3.47Å
156V98.7Very high97.9Very high4 Ų438 Ų382%0.02419%0.189CC..EExtended strand (participates in β ladder)trans-130.3147.9-177.4-66.80000111.5M67 V84 V137 F144 A146 T154 E162M67-V156 HydrophobicContact CE-CG2 4.14Å; M67-V156 HydrophobicContact SD-CB 4.34Å; M67-V156 HydrophobicContact SD-CG2 4.11Å; V84-V156 HydrophobicContact CG1-CG1 4.32Å; V137-V156 HydrophobicContact CG2-CG2 4.28Å; F144-V156 HydrophobicContact CB-CG2 4.24Å; F144-V156 PolarHBondContact O-N 3.49Å; A146-V156 HydrophobicContact CB-CG1 4.13Å; T154-V156 HydrophobicContact CG2-CG1 4.36Å; T154-V156 PolarHBondContact O-N 3.13Å; V156-E162 CarbonylContact C-O 3.58Å; V156-E162 WeakPolarHBondContact CA-O 3.17Å
157N98.4Very high97.9Very high49 Ų4938.3 Ų38.326%0.26219%0.191SC..  trans-84.6117167.3-175.9-44.5000108.6D159 T160 L161 E162 L164N157-D159 VanDerWaalsContact C-N 3.3Å; N157-D159 PolarHBondContact O-N 3.47Å; N157-D159 WeakPolarHBondContact OD1-CA 3.45Å; N157-D159 WeakPolarHBondContact OD1-CB 3.09Å; N157-D159 PolarHBondContact OD1-N 3.02Å; N157-T160 WeakPolarHBondContact CB-OG1 3.49Å; N157-T160 VanDerWaalsContact CG-OG1 3.25Å; N157-T160 PolarHBondContact OD1-N 2.71Å; N157-T160 PolarHBondContact OD1-OG1 3.08Å; N157-L161 WeakPolarHBondContact O-CA 3.48Å; N157-L161 PolarHBondContact O-N 3.19Å; N157-E162 HydrophobicContact CB-CB 4.4Å; N157-E162 PolarHBondContact N-O 3.37Å; N157-L164 HydrophobicContact CB-CD1 4.16Å; N157-L164 HydrophobicContact CB-CD2 4.33Å; N157-L164 HydrophobicContact CB-CG 4.34Å
158T97.3Very high97.9Very high5 Ų539.9 Ų39.93%0.03120%0.199CC..THydrogen-bonded Turntrans-77.3-15.5-176.449.70000114.2L43 M67 K69 F144 K531L43-T158 HydrophobicContact CD1-CG2 3.41Å; L43-T158 VanDerWaalsContact CD1-CG2 3.41Å; M67-T158 HydrophobicContact CE-CG2 4.26Å; K69-T158 WeakPolarHBondContact CD-O 3.19Å; F144-T158 HydrophobicContact CB-CG2 3.49Å; F144-T158 VanDerWaalsContact CB-CG2 3.49Å; F144-T158 HydrophobicContact CD1-CG2 3.72Å; F144-T158 HydrophobicContact CD2-CG2 3.65Å; F144-T158 HydrophobicContact CE1-CG2 4.34Å; F144-T158 HydrophobicContact CE2-CG2 4.3Å; F144-T158 HydrophobicContact CG-CG2 3.32Å; T158-K531 PolarHBondContact OG1-NZ 3.03Å
159D96.3Very high97.8Very high94 Ų9439.2 Ų39.250%0.50320%0.195SC..THydrogen-bonded Turntrans-84.8-41.9177.7-56.6-31.4000110.7K69 N157 K531K69-D159 PolarHBondContact NZ-O 2.87Å; N157-D159 VanDerWaalsContact C-N 3.3Å; N157-D159 PolarHBondContact O-N 3.47Å; N157-D159 WeakPolarHBondContact OD1-CA 3.45Å; N157-D159 WeakPolarHBondContact OD1-CB 3.09Å; N157-D159 PolarHBondContact OD1-N 3.02Å; D159-K531 IonicContact OD1-NZ 3.23Å; D159-K531 PolarHBondContact OD1-NZ 3.44Å; D159-K531 IonicContact OD2-NZ 3.34Å
160T97.5Very high97.7Very high52 Ų5239.3 Ų39.332%0.31920%0.201SC..THydrogen-bonded Turntrans-101.9-9.5-178.166.40000114.7Y80 N157 E162Y80-T160 WeakPolarHBondContact CE1-O 3.41Å; N157-T160 WeakPolarHBondContact CB-OG1 3.49Å; N157-T160 VanDerWaalsContact CG-OG1 3.25Å; N157-T160 PolarHBondContact OD1-N 2.71Å; N157-T160 PolarHBondContact OD1-OG1 3.08Å; T160-E162 PolarHBondContact O-N 2.84Å; T160-E162 WeakPolarHBondContact OG1-CB 3.38Å; T160-E162 VanDerWaalsContact OG1-CG 3.3Å; T160-E162 WeakPolarHBondContact OG1-CG 3.43Å; T160-E162 PolarHBondContact OG1-N 2.84Å; T160-E162 PolarHBondContact OG1-OE2 2.8Å; T160-E162 VanDerWaalsContact OG1-OE2 3.1Å
161L98.4Very high97.7Very high3 Ų344.5 Ų44.52%0.01623%0.228CC..  trans5821.4-170.4-48.6-174000113.8L43 M67 K69 Y80 K82 N157L43-L161 HydrophobicContact CD2-CD2 4.08Å; M67-L161 HydrophobicContact CE-CD2 3.94Å; M67-L161 HydrophobicContact CG-CD2 4.12Å; M67-L161 HydrophobicContact SD-CD2 3.74Å; K69-L161 HydrophobicContact CB-CD1 3.91Å; K69-L161 HydrophobicContact CB-CD2 4.05Å; K69-L161 HydrophobicContact CB-CG 4.4Å; K69-L161 HydrophobicContact CD-CD2 4.25Å; Y80-L161 HydrophobicContact CD1-CB 4.4Å; Y80-L161 HydrophobicContact CD1-CD1 3.47Å; Y80-L161 VanDerWaalsContact CD1-CD1 3.47Å; Y80-L161 HydrophobicContact CD1-CG 3.79Å; Y80-L161 HydrophobicContact CE1-CB 4.23Å; Y80-L161 HydrophobicContact CE1-CD1 4.04Å; Y80-L161 HydrophobicContact CE1-CG 4.11Å; Y80-L161 HydrophobicContact CG-CD1 4.24Å; K82-L161 HydrophobicContact CB-CB 3.87Å; K82-L161 HydrophobicContact CB-CD1 4.49Å; N157-L161 WeakPolarHBondContact O-CA 3.48Å; N157-L161 PolarHBondContact O-N 3.19Å
162E98.4Very high97.7Very high89 Ų8947.4 Ų47.442%0.41624%0.24SC..  trans-78.5139.7177.7-72.1175.115100111.9K82 V156 N157 T160K82-E162 IonicContact NZ-OE1 2.66Å; V156-E162 CarbonylContact C-O 3.58Å; V156-E162 WeakPolarHBondContact CA-O 3.17Å; N157-E162 HydrophobicContact CB-CB 4.4Å; N157-E162 PolarHBondContact N-O 3.37Å; T160-E162 PolarHBondContact O-N 2.84Å; T160-E162 WeakPolarHBondContact OG1-CB 3.38Å; T160-E162 VanDerWaalsContact OG1-CG 3.3Å; T160-E162 WeakPolarHBondContact OG1-CG 3.43Å; T160-E162 PolarHBondContact OG1-N 2.84Å; T160-E162 PolarHBondContact OG1-OE2 2.8Å; T160-E162 VanDerWaalsContact OG1-OE2 3.1Å
163T98.6Very high97.5Very high37 Ų3745.6 Ų45.623%0.22723%0.234CC..EExtended strand (participates in β ladder)trans-77.5128.7171.9-56.70000110V84 R85 T154V84-T163 HydrophobicContact CG1-CG2 4.32Å; R85-T163 HydrophobicContact CB-CG2 4.13Å; R85-T163 PolarHBondContact N-OG1 2.97Å; T154-T163 HydrophobicContact CG2-CG2 3.48Å; T154-T163 VanDerWaalsContact CG2-CG2 3.48Å
164L98.3Very high97.3Very high94 Ų9449.8 Ų49.849%0.49226%0.257SS..EExtended strand (participates in β ladder)trans-105.6-57.5-174.9-58.9-179.8000112.1K155 N157K155-L164 HydrophobicContact CB-CB 4.31Å; K155-L164 HydrophobicContact CD-CB 4.49Å; K155-L164 HydrophobicContact CD-CD1 4.42Å; K155-L164 HydrophobicContact CG-CB 4.19Å; K155-L164 HydrophobicContact CG-CD1 4.16Å; K155-L164 WeakPolarHBondContact O-CB 3.48Å; K155-L164 PolarHBondContact O-N 3.42Å; N157-L164 HydrophobicContact CB-CD1 4.16Å; N157-L164 HydrophobicContact CB-CD2 4.33Å; N157-L164 HydrophobicContact CB-CG 4.34Å
165K97.6Very high97Very high116 Ų11650 Ų5050%0.50426%0.257SS..EExtended strand (participates in β ladder)trans-154.3134.2-170.9-179-179.8175.8-169.20112K155 V167K155-K165 HydrophobicContact CB-CB 4.18Å; K155-K165 WeakPolarHBondContact CB-O 3.18Å; K155-K165 PolarHBondContact N-O 3.35Å; K155-K165 PolarHBondContact O-N 3.47Å; K165-V167 HydrophobicContact CD-CG2 4.35Å; K165-V167 HydrophobicContact CG-CG2 4.28Å
166K98.1Very high96.6Very high69 Ų6952.5 Ų52.530%0.327%0.273SS..EExtended strand (participates in β ladder)trans-78.7134.1164.6-180175.6-179.2160.90110.4D87 D131 Y152D87-K166 IonicContact OD2-NZ 2.78Å; D87-K166 PolarHBondContact OD2-NZ 2.83Å; D131-K166 HydrophobicContact CB-CD 4.42Å; D131-K166 WeakPolarHBondContact OD2-CD 3.1Å; D131-K166 WeakPolarHBondContact OD2-CE 3.29Å; D131-K166 IonicContact OD2-NZ 3.75Å; D131-K166 PolarHBondContact OD2-NZ 3Å; Y152-K166 HydrophobicContact CD1-CD 4.34Å; Y152-K166 HydrophobicContact CD1-CG 4.24Å; Y152-K166 VanDerWaalsContact CG-CE 3.41Å
167V98.1Very high96.3Very high7 Ų752.8 Ų52.84%0.04228%0.277CS..EExtended strand (participates in β ladder)trans-124.4130.6178.5179.70000108.9Y145 Y152 I153 K165 M169 F172 I221Y145-V167 HydrophobicContact CE1-CG2 3.95Å; Y152-V167 WeakPolarHBondContact CA-O 3.45Å; I153-V167 HydrophobicContact CD1-CB 4.42Å; I153-V167 HydrophobicContact CD1-CG1 4.48Å; I153-V167 HydrophobicContact CG1-CB 3.77Å; I153-V167 HydrophobicContact CG1-CG1 4.24Å; I153-V167 PolarHBondContact N-O 3.15Å; I153-V167 PolarHBondContact O-N 2.95Å; K165-V167 HydrophobicContact CD-CG2 4.35Å; K165-V167 HydrophobicContact CG-CG2 4.28Å; V167-M169 HydrophobicContact CG1-SD 4.35Å; V167-F172 HydrophobicContact CG1-CE2 3.7Å; V167-F172 HydrophobicContact CG1-CZ 4.45Å; V167-I221 HydrophobicContact CG1-CD1 4.34Å; V167-I221 HydrophobicContact CG1-CG2 4.47Å
168D97.6Very high96.2Very high34 Ų3450.9 Ų50.918%0.18227%0.266CS..EExtended strand (participates in β ladder)trans-100.1111.6174.3-172.5-18000109.4N151 Y152 C170 N171 F172N151-D168 PolarHBondContact ND2-OD1 2.84Å; N151-D168 PolarHBondContact ND2-OD2 3.02Å; Y152-D168 HydrophobicContact CD1-CB 3.91Å; Y152-D168 HydrophobicContact CE1-CB 3.67Å; Y152-D168 WeakPolarHBondContact CE1-OD2 3.29Å; D168-C170 PolarHBondContact O-N 3.15Å; D168-C170 VanDerWaalsContact OD1-CB 3.22Å; D168-C170 WeakPolarHBondContact OD1-CB 3.26Å; D168-C170 PolarHBondContact OD1-N 2.77Å; D168-N171 WeakPolarHBondContact O-CB 3.38Å; D168-N171 PolarHBondContact O-N 2.79Å; D168-F172 WeakPolarHBondContact O-CD2 3.41Å; D168-F172 WeakPolarHBondContact O-CE2 3.31Å
169M96.9Very high96.2Very high2 Ų250.8 Ų50.81%0.0127%0.266CS..G310 helixtrans-68-22-177.4-67.1-59.5-61.800113.3N151 I153 V167 N171 F172 V173 I175 I178 I210 I221N151-M169 WeakPolarHBondContact O-CB 3.05Å; N151-M169 PolarHBondContact O-N 2.78Å; I153-M169 HydrophobicContact CD1-CG 4.21Å; I153-M169 HydrophobicContact CD1-SD 3.65Å; I153-M169 HydrophobicContact CG1-CG 4.39Å; I153-M169 HydrophobicContact CG1-SD 4.32Å; I153-M169 HydrophobicContact CG2-CG 4.42Å; V167-M169 HydrophobicContact CG1-SD 4.35Å; M169-N171 PolarHBondContact O-N 2.83Å; M169-F172 PolarHBondContact O-N 2.68Å; M169-F172 VanDerWaalsContact O-N 3.09Å; M169-V173 HydrophobicContact CE-CG2 4.33Å; M169-V173 WeakPolarHBondContact O-CG2 3.37Å; M169-V173 PolarHBondContact O-N 2.76Å; M169-V173 VanDerWaalsContact O-N 3.15Å; M169-I175 HydrophobicContact CB-CD1 3.75Å; M169-I178 HydrophobicContact CG-CD1 4.22Å; M169-I210 HydrophobicContact CE-CD1 4.08Å; M169-I221 HydrophobicContact CE-CG2 4.22Å; M169-I221 HydrophobicContact SD-CG2 3.99Å
170C94.8Very high96.3Very high53 Ų5346.3 Ų46.336%0.35824%0.242SC..G310 helixtrans-63.5-21.4175.8-64.20000112.5N151 D168 F172 I175N151-C170 WeakPolarHBondContact CB-SG 3.31Å; D168-C170 PolarHBondContact O-N 3.15Å; D168-C170 VanDerWaalsContact OD1-CB 3.22Å; D168-C170 WeakPolarHBondContact OD1-CB 3.26Å; D168-C170 PolarHBondContact OD1-N 2.77Å; C170-F172 PolarHBondContact O-N 2.78Å; C170-I175 PolarHBondContact SG-O 2.76Å
171N96.5Very high96.4Very high124 Ų12445.4 Ų45.466%0.66323%0.234SC*.G310 helixtrans-73-16.6176.9-68.5-25.6000113.2D168 M169D168-N171 WeakPolarHBondContact O-CB 3.38Å; D168-N171 PolarHBondContact O-N 2.79Å; M169-N171 PolarHBondContact O-N 2.83Å
172F95.9Very high96.4Very high71 Ų7146.1 Ų46.131%0.31124%0.239SC..THydrogen-bonded Turntrans-115.4-33.8-173.4-52.4-77.4000112.7V167 D168 M169 C170 I221 E222V167-F172 HydrophobicContact CG1-CE2 3.7Å; V167-F172 HydrophobicContact CG1-CZ 4.45Å; D168-F172 WeakPolarHBondContact O-CD2 3.41Å; D168-F172 WeakPolarHBondContact O-CE2 3.31Å; M169-F172 PolarHBondContact O-N 2.68Å; M169-F172 VanDerWaalsContact O-N 3.09Å; C170-F172 PolarHBondContact O-N 2.78Å; F172-I221 HydrophobicContact CB-CG2 4.43Å; F172-I221 HydrophobicContact CD1-CG2 4.19Å; F172-I221 HydrophobicContact CD2-CG2 3.51Å; F172-I221 HydrophobicContact CE1-CG2 4.33Å; F172-I221 HydrophobicContact CE2-CG2 3.69Å; F172-I221 HydrophobicContact CG-CG2 3.77Å; F172-I221 HydrophobicContact CZ-CG2 4.09Å; F172-E222 HydrophobicContact CD1-CG 4.48Å; F172-E222 HydrophobicContact CE1-CG 3.98Å
173V94.9Very high96.4Very high11 Ų1143 Ų437%0.06723%0.225CC..SBendtrans-142.6150.5-176-78.10000111.9M169 I175 V208 S224M169-V173 HydrophobicContact CE-CG2 4.33Å; M169-V173 WeakPolarHBondContact O-CG2 3.37Å; M169-V173 PolarHBondContact O-N 2.76Å; M169-V173 VanDerWaalsContact O-N 3.15Å; V173-I175 HydrophobicContact CG2-CD1 4.11Å; V173-I175 HydrophobicContact CG2-CG1 4.05Å; V173-I175 PolarHBondContact O-N 2.92Å; V173-V208 HydrophobicContact CB-CG1 4.5Å; V173-V208 HydrophobicContact CB-CG2 4.27Å; V173-V208 HydrophobicContact CG1-CG1 4.07Å; V173-V208 HydrophobicContact CG2-CG1 4.09Å; V173-V208 HydrophobicContact CG2-CG2 4.04Å; V173-S224 VanDerWaalsContact CG1-CB 3.47Å
174N92.7Very high96.4Very high88 Ų8843.4 Ų43.447%0.47123%0.225SC..SBendtrans-7589.9177.8178.926.7000111C196 M197 N206N174-C196 VanDerWaalsContact O-CB 3.29Å; N174-C196 WeakPolarHBondContact O-CB 3.33Å; N174-M197 PolarHBondContact ND2-O 2.88Å; N174-N206 PolarHBondContact O-ND2 3.04Å
175I92.9Very high96.3Very high5 Ų541.7 Ų41.73%0.02621%0.214CC..  trans-145.9164.9174.458.1164.5000109.6M169 C170 V173 I178 N195 N206 V208M169-I175 HydrophobicContact CB-CD1 3.75Å; C170-I175 PolarHBondContact SG-O 2.76Å; V173-I175 HydrophobicContact CG2-CD1 4.11Å; V173-I175 HydrophobicContact CG2-CG1 4.05Å; V173-I175 PolarHBondContact O-N 2.92Å; I175-I178 HydrophobicContact CD1-CB 4.49Å; I175-I178 HydrophobicContact CD1-CG2 3.22Å; I175-N195 CarbonylContact C-O 3.49Å; I175-N195 VanDerWaalsContact CA-O 3.3Å; I175-N195 WeakPolarHBondContact CA-O 3.39Å; I175-N206 HydrophobicContact CG2-CB 4.33Å; I175-V208 HydrophobicContact CG2-CG2 3.78Å
176N91.6Very high96.1Very high96 Ų9643.8 Ų43.851%0.51323%0.226SC..SBendtrans-104.7-21.1171.4-62.9110.9000112.5N195 C196N176-N195 HydrophobicContact CB-CB 4.44Å; N176-N195 PolarHBondContact N-O 2.95Å; N176-N195 PolarHBondContact OD1-O 3.3Å; N176-C196 WeakPolarHBondContact OD1-CA 3.31Å
177G91.9Very high96Very high10 Ų1044.9 Ų44.910%0.10324%0.235CC..  trans-172.3166.4176.600000109.3T150 G194T150-G177 WeakPolarHBondContact O-CA 3.37Å; G177-G194 WeakPolarHBondContact O-CA 3.36Å
178I94.9Very high95.9Very high8 Ų845.7 Ų45.74%0.04124%0.244CC..  trans-122.1158.7173.555.1173.2000110E149 T150 I153 M169 I175 I193E149-I178 CarbonylContact C-O 3.57Å; E149-I178 VanDerWaalsContact CA-O 3.23Å; E149-I178 WeakPolarHBondContact CA-O 3.14Å; T150-I178 PolarHBondContact O-N 3.49Å; I153-I178 HydrophobicContact CG2-CD1 3.76Å; M169-I178 HydrophobicContact CG-CD1 4.22Å; I175-I178 HydrophobicContact CD1-CB 4.49Å; I175-I178 HydrophobicContact CD1-CG2 3.22Å; I178-I193 WeakPolarHBondContact CA-O 3.48Å
179T98.4Very high95.9Very high3 Ų344 Ų442%0.01824%0.236CC..  trans-71.7159.4170.575.50000111.7H181 N192 I193 V241 H242T179-H181 PolarHBondContact O-N 2.8Å; T179-H181 PolarHBondContact OG1-N 3.33Å; T179-N192 PolarHBondContact N-OD1 3.36Å; T179-N192 PolarHBondContact O-ND2 3.17Å; T179-N192 PolarHBondContact OG1-OD1 2.68Å; T179-I193 HydrophobicContact CG2-CG2 3.41Å; T179-I193 VanDerWaalsContact CG2-CG2 3.41Å; T179-I193 PolarHBondContact N-O 2.89Å; T179-I193 VanDerWaalsContact N-O 3.16Å; T179-V241 HydrophobicContact CG2-CG1 4.09Å; T179-H242 VanDerWaalsContact CB-O 3.3Å; T179-H242 WeakPolarHBondContact CB-O 3.23Å
180A98.4Very high96Very high0 Ų044 Ų440%024%0.235CC..SBendtrans-79.25.5168.900000113.7V135 N136 V147 E149 P182V135-A180 HydrophobicContact CB-CB 3.78Å; V135-A180 HydrophobicContact CG1-CB 3.36Å; N136-A180 HydrophobicContact CB-CB 4.15Å; N136-A180 WeakPolarHBondContact CB-O 3.14Å; N136-A180 PolarHBondContact ND2-O 2.68Å; V147-A180 HydrophobicContact CG2-CB 3.79Å; E149-A180 HydrophobicContact CG-CB 4.4Å; A180-P182 VanDerWaalsContact C-CD 3.44Å; A180-P182 WeakPolarHBondContact O-CD 3.29Å
181H98.6Very high96.2Very high33 Ų3342.1 Ų42.115%0.15322%0.221CC..  trans-124.364.4-172.6-66.4-80.6000112.1T179 H242 H314 H527T179-H181 PolarHBondContact O-N 2.8Å; T179-H181 PolarHBondContact OG1-N 3.33Å; H181-H242 AromaticContact CD2-CD2 3.41Å; H181-H242 PolarHBondContact CD2-CD2 3.33Å; H181-H242 VanDerWaalsContact CD2-CD2 3.41Å; H181-H242 AromaticContact CD2-NE2 3.3Å; H181-H242 PolarHBondContact CD2-NE2 2.92Å; H181-H242 VanDerWaalsContact CD2-NE2 3.3Å; H181-H242 PolarHBondContact CD2-O 2.98Å; H181-H242 AromaticContact CE1-NE2 3.98Å; H181-H242 AromaticContact NE2-CD2 3.5Å; H181-H242 PolarHBondContact NE2-CD2 2.96Å; H181-H242 AromaticContact NE2-CE1 3.82Å; H181-H242 AromaticContact NE2-NE2 2.91Å; H181-H242 PolarHBondContact NE2-NE2 2.77Å; H181-H314 AromaticContact CE1-CD2 3.6Å; H181-H314 AromaticContact CE1-NE2 3.63Å; H181-H314 AromaticContact NE2-CD2 3.79Å; H181-H314 AromaticContact NE2-NE2 3.61Å; H181-H527 AromaticContact CE1-CD2 3.5Å; H181-H527 AromaticContact CE1-CE1 3.4Å; H181-H527 PolarHBondContact CE1-CE1 3.23Å; H181-H527 VanDerWaalsContact CE1-CE1 3.4Å; H181-H527 AromaticContact CE1-CG 3.74Å; H181-H527 AromaticContact CE1-ND1 3.68Å; H181-H527 AromaticContact CE1-NE2 3.31Å; H181-H527 PolarHBondContact CE1-NE2 3.29Å; H181-H527 VanDerWaalsContact CE1-NE2 3.31Å; H181-H527 AromaticContact NE2-CD2 3.68Å; H181-H527 AromaticContact NE2-CE1 3.96Å; H181-H527 AromaticContact NE2-NE2 3.43Å; H181-H527 PolarHBondContact NE2-NE2 3.46Å
182P98.6Very high96.3Very high19 Ų1936.5 Ų36.512%0.12319%0.191CC..  trans-68.6151.2172.333-36.9000111.1Y138 A180 V190 Y191 N192Y138-P182 HydrophobicContact CD1-CG 3.52Å; Y138-P182 HydrophobicContact CD2-CG 3.76Å; Y138-P182 HydrophobicContact CE1-CG 3.55Å; Y138-P182 HydrophobicContact CE2-CG 3.81Å; Y138-P182 HydrophobicContact CG-CG 3.63Å; A180-P182 VanDerWaalsContact C-CD 3.44Å; A180-P182 WeakPolarHBondContact O-CD 3.29Å; P182-V190 HydrophobicContact CB-CG1 3.61Å; P182-V190 HydrophobicContact CG-CG1 4.32Å; P182-Y191 CarbonylContact C-O 3.38Å; P182-Y191 WeakPolarHBondContact CA-O 3.36Å; P182-Y191 VanDerWaalsContact CB-O 3.31Å; P182-Y191 WeakPolarHBondContact CB-O 3.3Å; P182-N192 HydrophobicContact CB-CB 4.19Å
183H98.8Very high96.4Very high24 Ų2433.1 Ų33.111%0.11118%0.176CC..EExtended strand (participates in β ladder)trans-89.5130.2163.9-78.5-69.5000109.9Y191 F244 M246 Y424H183-Y191 PolarHBondContact N-O 2.67Å; H183-Y191 PolarHBondContact O-N 2.8Å; H183-F244 HydrophobicContact CB-CZ 4.28Å; H183-F244 AromaticContact CD2-CE1 3.81Å; H183-F244 AromaticContact CD2-CE2 3.69Å; H183-F244 AromaticContact CD2-CZ 3.55Å; H183-F244 PolarHBondContact NE2-O 3.43Å; H183-M246 HydrophobicContact CB-CB 4.25Å; H183-M246 HydrophobicContact CB-CE 3.55Å; H183-M246 HydrophobicContact CB-SD 3.74Å; H183-M246 VanDerWaalsContact CD2-CB 3.43Å; H183-M246 WeakPolarHBondContact CD2-CB 3.41Å; H183-M246 PolarHBondContact NE2-N 2.68Å; H183-Y424 AromaticContact ND1-CE2 3.76Å; H183-Y424 AromaticContact ND1-CZ 3.63Å; H183-Y424 PolarHBondContact ND1-OH 3.02Å
184I98.3Very high96.5Very high44 Ų4432.8 Ų32.823%0.22618%0.175CC..EExtended strand (participates in β ladder)trans-115.3125.5178.9-53.7-178.2000108.9Y138 P139 T189 V190 Y424Y138-I184 HydrophobicContact CD2-CD1 4.28Å; P139-I184 HydrophobicContact CG-CD1 3.89Å; I184-T189 WeakPolarHBondContact CA-O 3.02Å; I184-V190 HydrophobicContact CG1-CG1 4.32Å; I184-V190 HydrophobicContact CG1-CG2 4.2Å; I184-V190 HydrophobicContact CG2-CG2 4.49Å; I184-Y424 WeakPolarHBondContact O-CE1 3.42Å
185E96.6Very high96.5Very high59 Ų5930.2 Ų30.228%0.27616%0.161SC..  trans-81.5164.9175.7-60.4-157.6105.500111.9D187 G188 T189 Y191 M246 K295E185-D187 WeakPolarHBondContact CB-OD1 3.46Å; E185-D187 PolarHBondContact O-N 2.81Å; E185-G188 PolarHBondContact O-N 2.84Å; E185-T189 PolarHBondContact N-O 2.68Å; E185-Y191 HydrophobicContact CG-CD2 4.34Å; E185-Y191 HydrophobicContact CG-CE2 4.13Å; E185-Y191 WeakPolarHBondContact OE2-CE2 3.46Å; E185-M246 HydrophobicContact CG-CE 4.11Å; E185-K295 VanDerWaalsContact CD-NZ 3.34Å; E185-K295 IonicContact OE1-NZ 2.81Å; E185-K295 PolarHBondContact OE1-NZ 2.84Å; E185-K295 IonicContact OE2-NZ 3.48Å
186Q93.9Very high96.5Very high159 Ų15930 Ų3074%0.74316%0.16SC*.THydrogen-bonded Turntrans-60.6-28.2-180-67-176.2-9.100113.5G188 Q425Q186-G188 VanDerWaalsContact C-N 3.25Å; Q186-G188 PolarHBondContact O-N 2.84Å; Q186-Q425 PolarHBondContact NE2-O 2.82Å
187D95.3Very high96.2Very high93 Ų9330.1 Ų30.150%0.49716%0.159SC..THydrogen-bonded Turntrans-79.5-7.817776-20.5000113.2E185 T189 P212E185-D187 WeakPolarHBondContact CB-OD1 3.46Å; E185-D187 PolarHBondContact O-N 2.81Å; D187-T189 VanDerWaalsContact CG-OG1 3.28Å; D187-T189 WeakPolarHBondContact OD1-CB 3.41Å; D187-T189 PolarHBondContact OD1-N 3.5Å; D187-T189 PolarHBondContact OD1-OG1 3.33Å; D187-T189 PolarHBondContact OD2-OG1 3.12Å; D187-P212 WeakPolarHBondContact O-CB 3.47Å
188G96.6Very high95.6Very high23 Ų2330.1 Ų30.124%0.23716%0.159CC..SBendtrans92.45.4-175.400000114.7E185 Q186 V190E185-G188 PolarHBondContact O-N 2.84Å; Q186-G188 VanDerWaalsContact C-N 3.25Å; Q186-G188 PolarHBondContact O-N 2.84Å; G188-V190 PolarHBondContact O-N 2.93Å
189T98.3Very high94.6Very high0 Ų038.6 Ų38.60%020%0.195CC..  trans-62.9131.1170.4-61.40000109.6I184 E185 D187 Y191 R209 P212I184-T189 WeakPolarHBondContact CA-O 3.02Å; E185-T189 PolarHBondContact N-O 2.68Å; D187-T189 VanDerWaalsContact CG-OG1 3.28Å; D187-T189 WeakPolarHBondContact OD1-CB 3.41Å; D187-T189 PolarHBondContact OD1-N 3.5Å; D187-T189 PolarHBondContact OD1-OG1 3.33Å; D187-T189 PolarHBondContact OD2-OG1 3.12Å; T189-Y191 HydrophobicContact CG2-CD2 3.94Å; T189-Y191 HydrophobicContact CG2-CE2 3.36Å; T189-R209 HydrophobicContact CG2-CG 3.72Å; T189-R209 PolarHBondContact OG1-NH2 3.35Å; T189-P212 WeakPolarHBondContact OG1-CD 3.35Å
190V98.7Very high93.4Very high1 Ų141.4 Ų41.41%0.00623%0.225CC..EExtended strand (participates in β ladder)trans-109.2128.5178.9-173.90000109.7Y138 I140 P182 I184 G188 R209 I210Y138-V190 HydrophobicContact CE2-CG1 4.33Å; I140-V190 HydrophobicContact CG1-CG2 4.36Å; P182-V190 HydrophobicContact CB-CG1 3.61Å; P182-V190 HydrophobicContact CG-CG1 4.32Å; I184-V190 HydrophobicContact CG1-CG1 4.32Å; I184-V190 HydrophobicContact CG1-CG2 4.2Å; I184-V190 HydrophobicContact CG2-CG2 4.49Å; G188-V190 PolarHBondContact O-N 2.93Å; V190-R209 CarbonylContact O-C 3.58Å; V190-R209 WeakPolarHBondContact O-CA 3.34Å; V190-I210 HydrophobicContact CB-CB 4.16Å; V190-I210 PolarHBondContact N-O 2.98Å; V190-I210 PolarHBondContact O-N 3.06Å
191Y98.8Very high92.5Very high13 Ų1344.1 Ų44.15%0.05125%0.248CC..EExtended strand (participates in β ladder)trans-112.7135.3170.9-70.3-89.3000110.2P182 H183 E185 T189 I207 V208 R209 V227 M246 F251 K295P182-Y191 CarbonylContact C-O 3.38Å; P182-Y191 WeakPolarHBondContact CA-O 3.36Å; P182-Y191 VanDerWaalsContact CB-O 3.31Å; P182-Y191 WeakPolarHBondContact CB-O 3.3Å; H183-Y191 PolarHBondContact N-O 2.67Å; H183-Y191 PolarHBondContact O-N 2.8Å; E185-Y191 HydrophobicContact CG-CD2 4.34Å; E185-Y191 HydrophobicContact CG-CE2 4.13Å; E185-Y191 WeakPolarHBondContact OE2-CE2 3.46Å; T189-Y191 HydrophobicContact CG2-CD2 3.94Å; T189-Y191 HydrophobicContact CG2-CE2 3.36Å; Y191-I207 HydrophobicContact CD1-CG2 4.02Å; Y191-V208 CarbonylContact C-O 3.59Å; Y191-V208 VanDerWaalsContact CA-O 3.28Å; Y191-V208 WeakPolarHBondContact CA-O 3.45Å; Y191-R209 HydrophobicContact CD1-CB 3.92Å; Y191-R209 HydrophobicContact CD1-CG 4.2Å; Y191-R209 HydrophobicContact CE1-CB 3.67Å; Y191-R209 HydrophobicContact CE1-CG 3.67Å; Y191-R209 HydrophobicContact CE2-CG 4.4Å; Y191-R209 WeakPolarHBondContact OH-CD 3.44Å; Y191-R209 PolarHBondContact OH-NE 2.76Å; Y191-V227 HydrophobicContact CE1-CG2 4.08Å; Y191-M246 HydrophobicContact CD2-SD 3.78Å; Y191-M246 HydrophobicContact CE2-SD 4.43Å; Y191-M246 HydrophobicContact CG-SD 4.07Å; Y191-F251 AromaticContact CD1-CE1 3.85Å; Y191-F251 HydrophobicContact CD1-CE1 3.85Å; Y191-F251 HydrophobicContact CD1-CE2 4.5Å; Y191-F251 AromaticContact CD1-CZ 3.42Å; Y191-F251 HydrophobicContact CD1-CZ 3.42Å; Y191-F251 VanDerWaalsContact CD1-CZ 3.42Å; Y191-F251 HydrophobicContact CE1-CE1 4.31Å; Y191-F251 HydrophobicContact CE1-CE2 4.45Å; Y191-F251 AromaticContact CE1-CZ 3.53Å; Y191-F251 HydrophobicContact CE1-CZ 3.53Å; Y191-F251 HydrophobicContact CG-CE1 4.08Å; Y191-F251 HydrophobicContact CG-CZ 4.11Å; Y191-K295 WeakPolarHBondContact OH-CE 3.27Å
192N98.6Very high91.8Very high6 Ų644.9 Ų44.93%0.03226%0.255CS..EExtended strand (participates in β ladder)trans-141.9162.8174.9-153.5-24.7000110.4T179 P182 I207 V208T179-N192 PolarHBondContact N-OD1 3.36Å; T179-N192 PolarHBondContact O-ND2 3.17Å; T179-N192 PolarHBondContact OG1-OD1 2.68Å; P182-N192 HydrophobicContact CB-CB 4.19Å; N192-I207 CarbonylContact O-C 3.58Å; N192-I207 WeakPolarHBondContact O-CA 3.48Å; N192-V208 PolarHBondContact N-O 2.88Å; N192-V208 PolarHBondContact O-N 3.02Å
193I98.4Very high91.4Very high1 Ų144.4 Ų44.41%0.00525%0.251CS..EExtended strand (participates in β ladder)trans-117.1146.9176.5-168.1169.1000110.1I178 T179 N206 I207 F230 V241 F244 F253I178-I193 WeakPolarHBondContact CA-O 3.48Å; T179-I193 HydrophobicContact CG2-CG2 3.41Å; T179-I193 VanDerWaalsContact CG2-CG2 3.41Å; T179-I193 PolarHBondContact N-O 2.89Å; T179-I193 VanDerWaalsContact N-O 3.16Å; I193-N206 WeakPolarHBondContact CA-O 3.49Å; I193-I207 HydrophobicContact CB-CD1 3.76Å; I193-I207 HydrophobicContact CD1-CD1 3.97Å; I193-I207 HydrophobicContact CG1-CD1 3.89Å; I193-F230 HydrophobicContact CD1-CD2 4.21Å; I193-F230 HydrophobicContact CD1-CE2 4.47Å; I193-V241 HydrophobicContact CD1-CG1 4.31Å; I193-V241 HydrophobicContact CG2-CG1 3.62Å; I193-F244 HydrophobicContact CB-CD1 4Å; I193-F244 HydrophobicContact CB-CE1 4.44Å; I193-F244 HydrophobicContact CB-CG 4.28Å; I193-F244 HydrophobicContact CD1-CB 4.47Å; I193-F244 HydrophobicContact CG2-CB 4.14Å; I193-F244 HydrophobicContact CG2-CD1 3.59Å; I193-F244 HydrophobicContact CG2-CE1 4.31Å; I193-F244 HydrophobicContact CG2-CG 4.07Å; I193-F253 HydrophobicContact CD1-CB 4.11Å; I193-F253 HydrophobicContact CD1-CD1 4.49Å; I193-F253 HydrophobicContact CD1-CD2 3.72Å; I193-F253 HydrophobicContact CD1-CE2 4.35Å; I193-F253 HydrophobicContact CD1-CG 3.83Å
194G95.8Very high91.2Very high4 Ų443.3 Ų43.34%0.04125%0.246CC..EExtended strand (participates in β ladder)trans-154.7148.8178.800000113G177 Y205 N206G177-G194 WeakPolarHBondContact O-CA 3.36Å; G194-Y205 CarbonylContact O-C 3.42Å; G194-Y205 VanDerWaalsContact O-CA 3.31Å; G194-Y205 WeakPolarHBondContact O-CA 3.49Å; G194-N206 PolarHBondContact N-O 3.16Å; G194-N206 PolarHBondContact O-N 2.82Å
195N93.5Very high91.2Very high34 Ų3441.2 Ų41.218%0.18224%0.236CC..EExtended strand (participates in β ladder)trans-61.4143.4170.7-66-35.7000109.9I175 N176 Y205I175-N195 CarbonylContact C-O 3.49Å; I175-N195 VanDerWaalsContact CA-O 3.3Å; I175-N195 WeakPolarHBondContact CA-O 3.39Å; N176-N195 HydrophobicContact CB-CB 4.44Å; N176-N195 PolarHBondContact N-O 2.95Å; N176-N195 PolarHBondContact OD1-O 3.3Å; N195-Y205 WeakPolarHBondContact OD1-CD1 3.42Å; N195-Y205 WeakPolarHBondContact OD1-CE1 3.43Å
196C91.9Very high91.2Very high1 Ų138.6 Ų38.61%0.00722%0.223CC..EExtended strand (participates in β ladder)trans-150.1166.1175.969.90000112.4N174 N176 G198 A204 N206N174-C196 VanDerWaalsContact O-CB 3.29Å; N174-C196 WeakPolarHBondContact O-CB 3.33Å; N176-C196 WeakPolarHBondContact OD1-CA 3.31Å; C196-G198 PolarHBondContact O-N 3.48Å; C196-A204 PolarHBondContact N-O 2.94Å; C196-A204 PolarHBondContact O-N 3.41Å; C196-A204 PolarHBondContact SG-O 2.6Å; C196-N206 HydrophobicContact CB-CB 4.49Å; C196-N206 PolarHBondContact SG-ND2 3.42Å; C196-N206 PolarHBondContact SG-OD1 2.98Å
197M85.1Confident91.5Very high97 Ų9731 Ų3148%0.47819%0.188SC..EExtended strand (participates in β ladder)trans-79.4115.6163.1-168.561.159.400109.8N174 L203N174-M197 PolarHBondContact ND2-O 2.88Å; M197-L203 HydrophobicContact CE-CD2 3.83Å; M197-L203 HydrophobicContact SD-CD2 4.33Å
198G79.7Confident91.6Very high11 Ų1126.7 Ų26.711%0.11317%0.165CC..  trans-85.4-177.3175.200000113.5C196 T202C196-G198 PolarHBondContact O-N 3.48Å; G198-T202 VanDerWaalsContact CA-O 3.29Å; G198-T202 WeakPolarHBondContact CA-O 3.32Å; G198-T202 PolarHBondContact N-O 3.36Å
199K74.7Confident91.7Very high185 Ų18528.1 Ų28.180%0.80416%0.163SC*.THydrogen-bonded Turntrans-64.5146178.6-65.4-178.1-176.9174.70111A201 T202K199-A201 VanDerWaalsContact C-N 3.34Å; K199-A201 PolarHBondContact O-N 3.35Å; K199-T202 PolarHBondContact O-OG1 3Å
200G73.9Confident91.7Very high62 Ų6228.4 Ų28.464%0.63917%0.165SC*.THydrogen-bonded Turntrans71.423176.500000115.2T202 R235G200-T202 VanDerWaalsContact C-N 3.35Å; G200-R235 PolarHBondContact O-NH2 3.4Å
201A77.5Confident91.6Very high58 Ų5828.8 Ų28.848%0.47917%0.167SC..SBendtrans55.450-175.200000111.8K199 R235K199-A201 VanDerWaalsContact C-N 3.34Å; K199-A201 PolarHBondContact O-N 3.35Å; A201-R235 PolarHBondContact O-NE 3.35Å
202T84.4Confident91.5Very high49 Ų4929.2 Ų29.230%0.30117%0.172SC..  trans-114.3150.1171.560.70000108.2G198 K199 G200 R235G198-T202 VanDerWaalsContact CA-O 3.29Å; G198-T202 WeakPolarHBondContact CA-O 3.32Å; G198-T202 PolarHBondContact N-O 3.36Å; K199-T202 PolarHBondContact O-OG1 3Å; G200-T202 VanDerWaalsContact C-N 3.35Å; T202-R235 HydrophobicContact CG2-CG 4.1Å
203L90.4Very high91.3Very high8 Ų831.7 Ų31.74%0.04219%0.187CC..EExtended strand (participates in β ladder)trans-79149170.6-61.6174.9000110.6M197 S232 R235 P238 L262M197-L203 HydrophobicContact CE-CD2 3.83Å; M197-L203 HydrophobicContact SD-CD2 4.33Å; L203-S232 WeakPolarHBondContact O-CB 3.31Å; L203-S232 PolarHBondContact O-N 2.85Å; L203-R235 WeakPolarHBondContact CG-O 3.07Å; L203-R235 PolarHBondContact N-O 3.31Å; L203-P238 HydrophobicContact CB-CB 4.47Å; L203-P238 HydrophobicContact CD1-CB 4.28Å; L203-P238 HydrophobicContact CD1-CG 3.76Å; L203-L262 HydrophobicContact CD1-CD1 3.4Å; L203-L262 HydrophobicContact CD1-CG 4.15Å; L203-L262 HydrophobicContact CD2-CD1 3.79Å; L203-L262 HydrophobicContact CG-CD1 4.2Å
204A95.3Very high90.8Very high2 Ų235 Ų352%0.01720%0.202CC..EExtended strand (participates in β ladder)trans-151.8177.6-177.300000109.8C196 Q229 F230C196-A204 PolarHBondContact N-O 2.94Å; C196-A204 PolarHBondContact O-N 3.41Å; C196-A204 PolarHBondContact SG-O 2.6Å; A204-Q229 HydrophobicContact CB-CG 3.62Å; A204-F230 WeakPolarHBondContact CA-O 3.36Å; A204-F230 VanDerWaalsContact CB-O 3.31Å; A204-F230 WeakPolarHBondContact CB-O 3.47Å
205Y97.4Very high90.5Very high0 Ų045 Ų450%025%0.245CC..EExtended strand (participates in β ladder)trans-125.4122.7176.5-41.1-93000109.5G194 N195 Q229 F230 P238 S239 V241 F253 E255G194-Y205 CarbonylContact O-C 3.42Å; G194-Y205 VanDerWaalsContact O-CA 3.31Å; G194-Y205 WeakPolarHBondContact O-CA 3.49Å; N195-Y205 WeakPolarHBondContact OD1-CD1 3.42Å; N195-Y205 WeakPolarHBondContact OD1-CE1 3.43Å; Y205-Q229 CarbonylContact O-C 3.53Å; Y205-Q229 WeakPolarHBondContact O-CA 3.18Å; Y205-F230 HydrophobicContact CD2-CB 4.09Å; Y205-F230 PolarHBondContact N-O 2.8Å; Y205-F230 PolarHBondContact O-N 3.24Å; Y205-P238 HydrophobicContact CE1-CB 3.9Å; Y205-P238 WeakPolarHBondContact OH-CA 3.42Å; Y205-S239 PolarHBondContact OH-N 3.19Å; Y205-V241 HydrophobicContact CD1-CG2 3.79Å; Y205-V241 HydrophobicContact CE1-CG2 3.72Å; Y205-F253 HydrophobicContact CD1-CE1 4.32Å; Y205-F253 HydrophobicContact CD1-CZ 4.04Å; Y205-F253 HydrophobicContact CD2-CD1 4.16Å; Y205-F253 AromaticContact CD2-CE1 3.38Å; Y205-F253 HydrophobicContact CD2-CE1 3.38Å; Y205-F253 AromaticContact CD2-CZ 3.9Å; Y205-F253 HydrophobicContact CD2-CZ 3.9Å; Y205-F253 HydrophobicContact CE1-CE1 4.37Å; Y205-F253 AromaticContact CE1-CZ 3.92Å; Y205-F253 HydrophobicContact CE1-CZ 3.92Å; Y205-F253 AromaticContact CE2-CE1 3.42Å; Y205-F253 HydrophobicContact CE2-CE1 3.42Å; Y205-F253 VanDerWaalsContact CE2-CE1 3.42Å; Y205-F253 AromaticContact CE2-CZ 3.77Å; Y205-F253 HydrophobicContact CE2-CZ 3.77Å; Y205-F253 AromaticContact CG-CE1 3.85Å; Y205-F253 HydrophobicContact CG-CE1 3.85Å; Y205-F253 HydrophobicContact CG-CZ 4.03Å; Y205-F253 AromaticContact CZ-CE1 3.95Å; Y205-F253 AromaticContact CZ-CZ 3.79Å; Y205-E255 PolarHBondContact OH-OE1 2.91Å
206N97.9Very high90.3Very high3 Ų348.4 Ų48.42%0.01626%0.263CS..EExtended strand (participates in β ladder)trans-97132.6177.9-79.8-19.9000110.3N174 I175 I193 G194 C196 V226 Q229N174-N206 PolarHBondContact O-ND2 3.04Å; I175-N206 HydrophobicContact CG2-CB 4.33Å; I193-N206 WeakPolarHBondContact CA-O 3.49Å; G194-N206 PolarHBondContact N-O 3.16Å; G194-N206 PolarHBondContact O-N 2.82Å; C196-N206 HydrophobicContact CB-CB 4.49Å; C196-N206 PolarHBondContact SG-ND2 3.42Å; C196-N206 PolarHBondContact SG-OD1 2.98Å; N206-V226 HydrophobicContact CB-CG1 3.95Å; N206-V226 HydrophobicContact CB-CG2 4.19Å; N206-Q229 WeakPolarHBondContact OD1-CB 3.38Å; N206-Q229 WeakPolarHBondContact OD1-CG 3.46Å; N206-Q229 PolarHBondContact OD1-NE2 3.37Å
207I98.4Very high90Very high0 Ų056.9 Ų56.90%030%0.3CS..EExtended strand (participates in β ladder)trans-81.6120.8160.2-62.8-67.2000108.1Y191 N192 I193 V226 V227 V228 F230 F244 F251Y191-I207 HydrophobicContact CD1-CG2 4.02Å; N192-I207 CarbonylContact O-C 3.58Å; N192-I207 WeakPolarHBondContact O-CA 3.48Å; I193-I207 HydrophobicContact CB-CD1 3.76Å; I193-I207 HydrophobicContact CD1-CD1 3.97Å; I193-I207 HydrophobicContact CG1-CD1 3.89Å; I207-V226 CarbonylContact O-C 3.59Å; I207-V226 WeakPolarHBondContact O-CA 3.37Å; I207-V227 HydrophobicContact CG2-CB 4.24Å; I207-V227 PolarHBondContact O-N 3.04Å; I207-V228 HydrophobicContact CB-CG1 3.85Å; I207-V228 HydrophobicContact CG1-CG1 3.72Å; I207-V228 PolarHBondContact N-O 3.1Å; I207-F230 HydrophobicContact CD1-CE2 3.97Å; I207-F230 HydrophobicContact CG1-CD2 4.24Å; I207-F230 HydrophobicContact CG1-CE2 3.63Å; I207-F244 HydrophobicContact CD1-CD2 3.85Å; I207-F244 HydrophobicContact CD1-CE2 3.86Å; I207-F244 HydrophobicContact CD1-CG 4.39Å; I207-F244 HydrophobicContact CD1-CZ 4.43Å; I207-F251 HydrophobicContact CG1-CD2 4.31Å; I207-F251 HydrophobicContact CG1-CG 4.38Å; I207-F251 HydrophobicContact CG2-CD2 4.29Å; I207-F251 HydrophobicContact CG2-CE1 4.19Å; I207-F251 HydrophobicContact CG2-CE2 3.87Å; I207-F251 HydrophobicContact CG2-CZ 3.83Å
208V98Very high90.3Very high2 Ų253.6 Ų53.61%0.01229%0.286CS..EExtended strand (participates in β ladder)trans-99.5137.6175.7176.40000108.9V173 I175 Y191 N192 I210 K225V173-V208 HydrophobicContact CB-CG1 4.5Å; V173-V208 HydrophobicContact CB-CG2 4.27Å; V173-V208 HydrophobicContact CG1-CG1 4.07Å; V173-V208 HydrophobicContact CG2-CG1 4.09Å; V173-V208 HydrophobicContact CG2-CG2 4.04Å; I175-V208 HydrophobicContact CG2-CG2 3.78Å; Y191-V208 CarbonylContact C-O 3.59Å; Y191-V208 VanDerWaalsContact CA-O 3.28Å; Y191-V208 WeakPolarHBondContact CA-O 3.45Å; N192-V208 PolarHBondContact N-O 2.88Å; N192-V208 PolarHBondContact O-N 3.02Å; V208-I210 HydrophobicContact CG1-CG1 4.32Å; V208-K225 CarbonylContact C-O 3.36Å; V208-K225 WeakPolarHBondContact CA-O 3.13Å
209R98.2Very high91Very high53 Ų5355.1 Ų55.120%0.229%0.292CS..EExtended strand (participates in β ladder)trans-116.6127170.5179.4-174.9-177.6-79.5-3.9109.9T189 V190 Y191 S224 K225 V227T189-R209 HydrophobicContact CG2-CG 3.72Å; T189-R209 PolarHBondContact OG1-NH2 3.35Å; V190-R209 CarbonylContact O-C 3.58Å; V190-R209 WeakPolarHBondContact O-CA 3.34Å; Y191-R209 HydrophobicContact CD1-CB 3.92Å; Y191-R209 HydrophobicContact CD1-CG 4.2Å; Y191-R209 HydrophobicContact CE1-CB 3.67Å; Y191-R209 HydrophobicContact CE1-CG 3.67Å; Y191-R209 HydrophobicContact CE2-CG 4.4Å; Y191-R209 WeakPolarHBondContact OH-CD 3.44Å; Y191-R209 PolarHBondContact OH-NE 2.76Å; R209-S224 WeakPolarHBondContact O-CA 3.36Å; R209-K225 HydrophobicContact CB-CG 4.35Å; R209-K225 PolarHBondContact N-O 3.48Å; R209-K225 PolarHBondContact O-N 2.8Å; R209-V227 HydrophobicContact CB-CG2 3.38Å; R209-V227 HydrophobicContact CG-CG2 4.42Å
210I98.4Very high92Very high6 Ų646.7 Ų46.73%0.03126%0.256CS..EExtended strand (participates in β ladder)trans-108.1120.6170-43.7-177.3000106.9I140 M169 V190 V208 P220I140-I210 HydrophobicContact CD1-CD1 3.95Å; I140-I210 HydrophobicContact CG2-CG2 3.76Å; M169-I210 HydrophobicContact CE-CD1 4.08Å; V190-I210 HydrophobicContact CB-CB 4.16Å; V190-I210 PolarHBondContact N-O 2.98Å; V190-I210 PolarHBondContact O-N 3.06Å; V208-I210 HydrophobicContact CG1-CG1 4.32Å; I210-P220 HydrophobicContact CG2-CB 3.96Å; I210-P220 WeakPolarHBondContact CG2-O 3.5Å
211P97.6Very high93.1Very high10 Ų1043.7 Ų43.77%0.06523%0.226CC..PPolyproline II helixtrans-66.5166.5179.929.7-34.9000111.6P220 K223P211-P220 VanDerWaalsContact O-CB 3.29Å; P211-P220 WeakPolarHBondContact O-CB 3.44Å; P211-K223 WeakPolarHBondContact CD-O 3.44Å; P211-K223 HydrophobicContact CG-CB 3.57Å
212P96.9Very high94Very high22 Ų2247 Ų4714%0.14323%0.231CC..PPolyproline II helixtrans-71.7173.9171.232.4-35.9000111.1D187 T189 Q214D187-P212 WeakPolarHBondContact O-CB 3.47Å; T189-P212 WeakPolarHBondContact OG1-CD 3.35Å; P212-Q214 PolarHBondContact O-N 2.86Å; P212-Q214 PolarHBondContact O-NE2 3.29Å
213T93.4Very high94.6Very high57 Ų5748.3 Ų48.335%0.3523%0.232SC..PPolyproline II helixtrans-53.1125174.4-56.30000110.8G141G141-T213 WeakPolarHBondContact CA-OG1 3.21Å
214Q89.4Confident94.9Very high70 Ų7048.6 Ų48.633%0.32724%0.235SC..PPolyproline II helixtrans-92.2158.6-178-61.4-60.5-6000110.7P212 D216 K217 K223P212-Q214 PolarHBondContact O-N 2.86Å; P212-Q214 PolarHBondContact O-NE2 3.29Å; Q214-D216 WeakPolarHBondContact CB-OD1 3.36Å; Q214-D216 PolarHBondContact O-N 3.31Å; Q214-K217 PolarHBondContact O-N 3.35Å; Q214-K223 HydrophobicContact CG-CD 4.02Å
215K88.8Confident95Very high216 Ų21654 Ų5494%0.93926%0.258SS*.THydrogen-bonded Turntrans-60.3-27.7-179.3-69.7-175.7179.9178.50113.7K217K215-K217 PolarHBondContact O-N 2.78Å
216D88.5Confident95Very high105 Ų10557 Ų5756%0.56128%0.276SS*.THydrogen-bonded Turntrans-77.3-2.5177.261-4.8000113.2Q214 S218 K223Q214-D216 WeakPolarHBondContact CB-OD1 3.36Å; Q214-D216 PolarHBondContact O-N 3.31Å; D216-S218 PolarHBondContact O-N 3.28Å; D216-S218 VanDerWaalsContact O-N 3.11Å; D216-S218 PolarHBondContact OD1-N 3.34Å; D216-S218 PolarHBondContact OD1-OG 2.78Å; D216-K223 VanDerWaalsContact CG-NZ 3.28Å; D216-K223 IonicContact OD1-NZ 3.99Å; D216-K223 PolarHBondContact OD1-NZ 3.48Å; D216-K223 IonicContact OD2-NZ 2.71Å; D216-K223 PolarHBondContact OD2-NZ 2.92Å
217K86.4Confident95Very high178 Ų17858.1 Ų58.177%0.77428%0.284SS*.  trans56.519.9-179.9-58.5-172.6173.8-168.50114.4Q214 K215Q214-K217 PolarHBondContact O-N 3.35Å; K215-K217 PolarHBondContact O-N 2.78Å
218S91.1Very high94.9Very high29 Ų2958.6 Ų58.620%0.20329%0.286CS..  trans-62.5148.8170.164.40000110D216 P220 K223D216-S218 PolarHBondContact O-N 3.28Å; D216-S218 VanDerWaalsContact O-N 3.11Å; D216-S218 PolarHBondContact OD1-N 3.34Å; D216-S218 PolarHBondContact OD1-OG 2.78Å; S218-P220 WeakPolarHBondContact O-CD 3.41Å; S218-K223 WeakPolarHBondContact OG-CE 3.45Å; S218-K223 PolarHBondContact OG-NZ 3Å
219D93.9Very high94.8Very high42 Ų4261.7 Ų61.723%0.22530%0.301CS..  trans-57120.2172.3-173.7-22.7000109.6I221 E222D219-I221 PolarHBondContact O-N 3.44Å; D219-I221 WeakPolarHBondContact OD1-CB 3.25Å; D219-I221 PolarHBondContact OD1-N 2.85Å; D219-E222 HydrophobicContact CB-CG 4.13Å; D219-E222 WeakPolarHBondContact O-CB 3.42Å; D219-E222 PolarHBondContact O-N 3.21Å; D219-E222 VanDerWaalsContact O-N 3.13Å
220P96.8Very high94.8Very high8 Ų859.2 Ų59.25%0.05229%0.292CS..G310 helixtrans-58.8-28-178.9-23.933.7000113.8I140 I210 P211 S218 E222 K223I140-P220 HydrophobicContact CG2-CB 4.18Å; I210-P220 HydrophobicContact CG2-CB 3.96Å; I210-P220 WeakPolarHBondContact CG2-O 3.5Å; P211-P220 VanDerWaalsContact O-CB 3.29Å; P211-P220 WeakPolarHBondContact O-CB 3.44Å; S218-P220 WeakPolarHBondContact O-CD 3.41Å; P220-E222 PolarHBondContact O-N 2.65Å; P220-K223 PolarHBondContact O-N 2.77Å
221I96.6Very high94.6Very high0 Ų061.5 Ų61.50%031%0.306CS..G310 helixtrans-61.9-34.3179.1-62.9178.4000111.1I140 Y145 I153 V167 M169 F172 D219 K223 S224I140-I221 HydrophobicContact CD1-CD1 4.01Å; I140-I221 HydrophobicContact CD1-CG1 4.16Å; I140-I221 HydrophobicContact CG2-CG1 3.97Å; Y145-I221 HydrophobicContact CE1-CD1 3.79Å; Y145-I221 HydrophobicContact CE2-CD1 4.13Å; Y145-I221 WeakPolarHBondContact OH-CD1 3.14Å; I153-I221 HydrophobicContact CD1-CD1 4.19Å; V167-I221 HydrophobicContact CG1-CD1 4.34Å; V167-I221 HydrophobicContact CG1-CG2 4.47Å; M169-I221 HydrophobicContact CE-CG2 4.22Å; M169-I221 HydrophobicContact SD-CG2 3.99Å; F172-I221 HydrophobicContact CB-CG2 4.43Å; F172-I221 HydrophobicContact CD1-CG2 4.19Å; F172-I221 HydrophobicContact CD2-CG2 3.51Å; F172-I221 HydrophobicContact CE1-CG2 4.33Å; F172-I221 HydrophobicContact CE2-CG2 3.69Å; F172-I221 HydrophobicContact CG-CG2 3.77Å; F172-I221 HydrophobicContact CZ-CG2 4.09Å; D219-I221 PolarHBondContact O-N 3.44Å; D219-I221 WeakPolarHBondContact OD1-CB 3.25Å; D219-I221 PolarHBondContact OD1-N 2.85Å; I221-K223 PolarHBondContact O-N 2.58Å; I221-K223 VanDerWaalsContact O-N 3.15Å; I221-S224 VanDerWaalsContact O-CB 3.22Å; I221-S224 WeakPolarHBondContact O-CB 3.26Å; I221-S224 PolarHBondContact O-N 2.8Å; I221-S224 VanDerWaalsContact O-N 3.07Å; I221-S224 PolarHBondContact O-OG 2.78Å
222E95.9Very high94.5Very high127 Ų12762 Ų6259%0.59331%0.31SS*.G310 helixtrans-64-20.4177.3-65.4-179.9174.700112.7F172 D219 P220F172-E222 HydrophobicContact CD1-CG 4.48Å; F172-E222 HydrophobicContact CE1-CG 3.98Å; D219-E222 HydrophobicContact CB-CG 4.13Å; D219-E222 WeakPolarHBondContact O-CB 3.42Å; D219-E222 PolarHBondContact O-N 3.21Å; D219-E222 VanDerWaalsContact O-N 3.13Å; P220-E222 PolarHBondContact O-N 2.65Å
223K96.6Very high94.3Very high76 Ų7663.3 Ų63.333%0.3332%0.323SS..G310 helixtrans-101.416179.3-64.3176.3174.7169.70112.4P211 Q214 D216 S218 P220 I221P211-K223 WeakPolarHBondContact CD-O 3.44Å; P211-K223 HydrophobicContact CG-CB 3.57Å; Q214-K223 HydrophobicContact CG-CD 4.02Å; D216-K223 VanDerWaalsContact CG-NZ 3.28Å; D216-K223 IonicContact OD1-NZ 3.99Å; D216-K223 PolarHBondContact OD1-NZ 3.48Å; D216-K223 IonicContact OD2-NZ 2.71Å; D216-K223 PolarHBondContact OD2-NZ 2.92Å; S218-K223 WeakPolarHBondContact OG-CE 3.45Å; S218-K223 PolarHBondContact OG-NZ 3Å; P220-K223 PolarHBondContact O-N 2.77Å; I221-K223 PolarHBondContact O-N 2.58Å; I221-K223 VanDerWaalsContact O-N 3.15Å
224S97.3Very high94.2Very high15 Ų1562.8 Ų62.811%0.10532%0.317CS..  trans-61139175.4-61.60000111.2V173 R209 I221V173-S224 VanDerWaalsContact CG1-CB 3.47Å; R209-S224 WeakPolarHBondContact O-CA 3.36Å; I221-S224 VanDerWaalsContact O-CB 3.22Å; I221-S224 WeakPolarHBondContact O-CB 3.26Å; I221-S224 PolarHBondContact O-N 2.8Å; I221-S224 VanDerWaalsContact O-N 3.07Å; I221-S224 PolarHBondContact O-OG 2.78Å
225K97Very high94.1Very high115 Ų11566 Ų6650%0.533%0.326SS..EExtended strand (participates in β ladder)trans-140.5151.2176.865.4178.3-176.8173.30112.1V208 R209V208-K225 CarbonylContact C-O 3.36Å; V208-K225 WeakPolarHBondContact CA-O 3.13Å; R209-K225 HydrophobicContact CB-CG 4.35Å; R209-K225 PolarHBondContact N-O 3.48Å; R209-K225 PolarHBondContact O-N 2.8Å
226V97.3Very high94.1Very high62 Ų6261.4 Ų61.438%0.37631%0.306SS..EExtended strand (participates in β ladder)trans-76.3131167.4178.40000108.7N206 I207N206-V226 HydrophobicContact CB-CG1 3.95Å; N206-V226 HydrophobicContact CB-CG2 4.19Å; I207-V226 CarbonylContact O-C 3.59Å; I207-V226 WeakPolarHBondContact O-CA 3.37Å
227V97.4Very high94.3Very high28 Ų2859.1 Ų59.117%0.1729%0.291CS..EExtended strand (participates in β ladder)trans-96.5-50.7179.5178.50000111Y191 I207 R209 F251Y191-V227 HydrophobicContact CE1-CG2 4.08Å; I207-V227 HydrophobicContact CG2-CB 4.24Å; I207-V227 PolarHBondContact O-N 3.04Å; R209-V227 HydrophobicContact CB-CG2 3.38Å; R209-V227 HydrophobicContact CG-CG2 4.42Å; V227-F251 HydrophobicContact CG1-CE2 4.12Å
228V97.3Very high94.7Very high10 Ų1050.8 Ų50.86%0.06126%0.255CS..EExtended strand (participates in β ladder)trans-149.3154.6-179.965.10000109.5I207 F230 F251 A293I207-V228 HydrophobicContact CB-CG1 3.85Å; I207-V228 HydrophobicContact CG1-CG1 3.72Å; I207-V228 PolarHBondContact N-O 3.1Å; V228-F230 HydrophobicContact CG1-CE2 4.47Å; V228-F251 HydrophobicContact CG1-CD2 4.02Å; V228-F251 HydrophobicContact CG1-CE2 4.44Å; V228-A293 HydrophobicContact CB-CB 4.33Å; V228-A293 HydrophobicContact CG1-CB 3.8Å; V228-A293 HydrophobicContact CG2-CB 3.8Å
229Q97.1Very high94.9Very high67 Ų6749.4 Ų49.431%0.31325%0.245SC..EExtended strand (participates in β ladder)trans-118.4125.7177.4-179.2167.7102.100109.7A204 Y205 N206A204-Q229 HydrophobicContact CB-CG 3.62Å; Y205-Q229 CarbonylContact O-C 3.53Å; Y205-Q229 WeakPolarHBondContact O-CA 3.18Å; N206-Q229 WeakPolarHBondContact OD1-CB 3.38Å; N206-Q229 WeakPolarHBondContact OD1-CG 3.46Å; N206-Q229 PolarHBondContact OD1-NE2 3.37Å
230F97Very high95Very high1 Ų148.1 Ų48.10%0.00424%0.238CC..EExtended strand (participates in β ladder)trans-90.5139.3170.4-65.3-68.7000110.7I193 A204 Y205 I207 V228 F251 F253 H291 A293 Y300I193-F230 HydrophobicContact CD1-CD2 4.21Å; I193-F230 HydrophobicContact CD1-CE2 4.47Å; A204-F230 WeakPolarHBondContact CA-O 3.36Å; A204-F230 VanDerWaalsContact CB-O 3.31Å; A204-F230 WeakPolarHBondContact CB-O 3.47Å; Y205-F230 HydrophobicContact CD2-CB 4.09Å; Y205-F230 PolarHBondContact N-O 2.8Å; Y205-F230 PolarHBondContact O-N 3.24Å; I207-F230 HydrophobicContact CD1-CE2 3.97Å; I207-F230 HydrophobicContact CG1-CD2 4.24Å; I207-F230 HydrophobicContact CG1-CE2 3.63Å; V228-F230 HydrophobicContact CG1-CE2 4.47Å; F230-F251 HydrophobicContact CE2-CB 4.49Å; F230-F251 HydrophobicContact CZ-CB 4.05Å; F230-F253 HydrophobicContact CB-CD1 4.01Å; F230-F253 HydrophobicContact CD2-CB 3.94Å; F230-F253 HydrophobicContact CD2-CD1 4.17Å; F230-F253 HydrophobicContact CD2-CG 4.32Å; F230-F253 HydrophobicContact CE2-CB 3.81Å; F230-F253 HydrophobicContact CG-CB 4.35Å; F230-F253 HydrophobicContact CG-CD1 4.05Å; F230-F253 HydrophobicContact CZ-CB 4.12Å; F230-H291 HydrophobicContact CD1-CB 3.48Å; F230-H291 VanDerWaalsContact CD1-CB 3.48Å; F230-H291 HydrophobicContact CE1-CB 3.72Å; F230-H291 HydrophobicContact CG-CB 4.24Å; F230-A293 HydrophobicContact CE1-CB 3.57Å; F230-A293 HydrophobicContact CZ-CB 3.6Å; F230-Y300 AromaticContact CD1-CD2 3.61Å; F230-Y300 HydrophobicContact CD1-CD2 3.61Å; F230-Y300 AromaticContact CD1-CE2 3.88Å; F230-Y300 HydrophobicContact CD1-CE2 3.88Å; F230-Y300 AromaticContact CE1-CD2 3.95Å; F230-Y300 HydrophobicContact CE1-CD2 3.95Å; F230-Y300 HydrophobicContact CE1-CE2 4.37Å
231P95.1Very high95Very high53 Ų5348.5 Ų48.534%0.34424%0.24SC..EExtended strand (participates in β ladder)trans-71.2152.717431.7-34.5000111Y300P231-Y300 HydrophobicContact CG-CE1 4.03Å; P231-Y300 HydrophobicContact CG-CE2 4.38Å
232S94.4Very high95.1Very high20 Ų2049 Ų4914%0.1424%0.242CC..PPolyproline II helixtrans-89.8138.2164.6179.20000110.5L203 E234L203-S232 WeakPolarHBondContact O-CB 3.31Å; L203-S232 PolarHBondContact O-N 2.85Å; S232-E234 WeakPolarHBondContact CB-O 3.5Å; S232-E234 PolarHBondContact O-N 2.84Å; S232-E234 PolarHBondContact OG-N 2.98Å; S232-E234 PolarHBondContact OG-O 3.2Å
233A92.9Very high95.2Very high51 Ų5143.3 Ų43.342%0.42122%0.216SC..SBendtrans-62.5-31.917300000112.8E255 I289A233-E255 WeakPolarHBondContact CB-OE2 3.31Å; A233-E255 PolarHBondContact N-OE1 3.35Å; A233-E255 PolarHBondContact N-OE2 2.78Å; A233-E255 VanDerWaalsContact N-OE2 3.12Å; A233-I289 HydrophobicContact CB-CD1 3.48Å; A233-I289 VanDerWaalsContact CB-CD1 3.48Å
234E92Very high95.3Very high45 Ų4539.7 Ų39.721%0.2120%0.201CC..SBendtrans-116.1131.3176.6-73-168.9-118.200111.4S232 F236 K237 K259 N283S232-E234 WeakPolarHBondContact CB-O 3.5Å; S232-E234 PolarHBondContact O-N 2.84Å; S232-E234 PolarHBondContact OG-N 2.98Å; S232-E234 PolarHBondContact OG-O 3.2Å; E234-F236 VanDerWaalsContact C-N 3.29Å; E234-F236 PolarHBondContact O-N 2.97Å; E234-K237 HydrophobicContact CB-CB 4Å; E234-K237 PolarHBondContact O-N 3.43Å; E234-K237 WeakPolarHBondContact OE2-CD 3.3Å; E234-K237 IonicContact OE2-NZ 3.97Å; E234-K259 WeakPolarHBondContact OE1-CE 3.35Å; E234-N283 PolarHBondContact OE1-ND2 3.13Å
235R87.6Confident95.4Very high138 Ų13839 Ų3952%0.52120%0.196SC..THydrogen-bonded Turntrans-57.3-37.3-171.8-179168.7-174.1174.26.4114.6G200 A201 T202 L203G200-R235 PolarHBondContact O-NH2 3.4Å; A201-R235 PolarHBondContact O-NE 3.35Å; T202-R235 HydrophobicContact CG2-CG 4.1Å; L203-R235 WeakPolarHBondContact CG-O 3.07Å; L203-R235 PolarHBondContact N-O 3.31Å
236F88.1Confident95.5Very high119 Ų11934.1 Ų34.152%0.52218%0.175SC..THydrogen-bonded Turntrans-124.110.5-172.6-59.3-63.9000113.6E234E234-F236 VanDerWaalsContact C-N 3.29Å; E234-F236 PolarHBondContact O-N 2.97Å
237K92.4Very high95.5Very high57 Ų5731.2 Ų31.225%0.24816%0.157CC..  trans-137.190.7-178.5-61.9-173.4-166.1169.10109.2E234 K259 I260 E281E234-K237 HydrophobicContact CB-CB 4Å; E234-K237 PolarHBondContact O-N 3.43Å; E234-K237 WeakPolarHBondContact OE2-CD 3.3Å; E234-K237 IonicContact OE2-NZ 3.97Å; K237-K259 HydrophobicContact CB-CB 4.2Å; K237-K259 HydrophobicContact CB-CD 4.47Å; K237-K259 HydrophobicContact CB-CG 4.45Å; K237-I260 WeakPolarHBondContact CA-O 3.33Å; K237-E281 VanDerWaalsContact CD-OE1 3.27Å; K237-E281 WeakPolarHBondContact CD-OE1 3.37Å; K237-E281 WeakPolarHBondContact CE-OE1 3.34Å; K237-E281 IonicContact NZ-OE1 3.06Å; K237-E281 PolarHBondContact NZ-OE1 3.44Å
238P94.2Very high95.5Very high3 Ų336.3 Ų36.32%0.01918%0.179CC..PPolyproline II helixtrans-69.9151.3173.631.1-20.7000108L203 Y205 K259 I260L203-P238 HydrophobicContact CB-CB 4.47Å; L203-P238 HydrophobicContact CD1-CB 4.28Å; L203-P238 HydrophobicContact CD1-CG 3.76Å; Y205-P238 HydrophobicContact CE1-CB 3.9Å; Y205-P238 WeakPolarHBondContact OH-CA 3.42Å; P238-K259 CarbonylContact O-C 3.5Å; P238-K259 WeakPolarHBondContact O-CA 3.41Å; P238-I260 VanDerWaalsContact CD-O 3.26Å; P238-I260 WeakPolarHBondContact CD-O 3.47Å; P238-I260 HydrophobicContact CG-CB 4.27Å; P238-I260 PolarHBondContact O-N 3.25Å
239S96.4Very high95.5Very high0 Ų039.5 Ų39.50%020%0.196CC..BIsolated β-bridgetrans-70.9155167.9-67.40000111Y205 E255 T256 V258 K259Y205-S239 PolarHBondContact OH-N 3.19Å; S239-E255 WeakPolarHBondContact OG-CG 3.47Å; S239-T256 WeakPolarHBondContact CB-O 3.42Å; S239-T256 PolarHBondContact OG-O 2.73Å; S239-V258 CarbonylContact C-O 3.5Å; S239-V258 WeakPolarHBondContact CA-O 3.4Å; S239-V258 WeakPolarHBondContact CB-O 3.42Å; S239-K259 WeakPolarHBondContact OG-CD 3.38Å; S239-K259 WeakPolarHBondContact OG-CE 3.43Å; S239-K259 PolarHBondContact OG-NZ 2.95Å
240Y96.4Very high95.6Very high16 Ų1638 Ų386%0.06319%0.188CC..PPolyproline II helixtrans-63.5134.3163.7-177.1-123.5000110.1E149 H242 V258 F280 F313 F337 Y339E149-Y240 WeakPolarHBondContact OE2-CE2 3.45Å; E149-Y240 VanDerWaalsContact OE2-CZ 3.24Å; E149-Y240 PolarHBondContact OE2-OH 3.42Å; Y240-H242 HydrophobicContact CE1-CB 3.93Å; Y240-H242 AromaticContact CZ-ND1 3.91Å; Y240-H242 PolarHBondContact OH-ND1 3.16Å; Y240-V258 PolarHBondContact N-O 2.83Å; Y240-F280 AromaticContact CD2-CE1 3.73Å; Y240-F280 HydrophobicContact CD2-CE1 3.73Å; Y240-F280 HydrophobicContact CD2-CZ 4.01Å; Y240-F280 AromaticContact CG-CE1 3.91Å; Y240-F280 HydrophobicContact CG-CE1 3.91Å; Y240-F313 AromaticContact CE1-CD1 3.97Å; Y240-F313 HydrophobicContact CE1-CD1 3.97Å; Y240-F313 AromaticContact CE1-CE1 3.85Å; Y240-F313 HydrophobicContact CE1-CE1 3.85Å; Y240-F337 AromaticContact CD1-CE2 3.91Å; Y240-F337 HydrophobicContact CD1-CE2 3.91Å; Y240-F337 HydrophobicContact CD1-CZ 4.23Å; Y240-F337 HydrophobicContact CE1-CE2 4.13Å; Y240-F337 HydrophobicContact CE1-CZ 4.34Å; Y240-Y339 HydrophobicContact CE1-CE2 4.22Å; Y240-Y339 AromaticContact CZ-CE2 3.98Å; Y240-Y339 WeakPolarHBondContact OH-CE2 3.27Å; Y240-Y339 PolarHBondContact OH-OH 3.37Å
241V96.4Very high95.7Very high15 Ų1538 Ų389%0.09119%0.187CC..  trans-130.6116.1179.4-171.60000108.4T179 I193 Y205 F253T179-V241 HydrophobicContact CG2-CG1 4.09Å; I193-V241 HydrophobicContact CD1-CG1 4.31Å; I193-V241 HydrophobicContact CG2-CG1 3.62Å; Y205-V241 HydrophobicContact CD1-CG2 3.79Å; Y205-V241 HydrophobicContact CE1-CG2 3.72Å; V241-F253 HydrophobicContact CB-CE2 4.25Å; V241-F253 HydrophobicContact CG1-CD2 4.17Å; V241-F253 HydrophobicContact CG1-CE2 3.79Å; V241-F253 HydrophobicContact CG2-CE2 3.46Å; V241-F253 VanDerWaalsContact CG2-CE2 3.46Å; V241-F253 HydrophobicContact CG2-CZ 3.76Å
242H98.2Very high95.8Very high11 Ų1135.4 Ų35.45%0.05117%0.171CC..SBendtrans-105.6-32.9-179.8-170.394.2000112.1E149 T179 H181 Y240 F313 H314 Y339E149-H242 IonicContact OE1-CE1 3.67Å; E149-H242 IonicContact OE1-CG 3.59Å; E149-H242 IonicContact OE1-ND1 2.8Å; E149-H242 PolarHBondContact OE1-ND1 3.25Å; E149-H242 VanDerWaalsContact OE1-ND1 3.15Å; T179-H242 VanDerWaalsContact CB-O 3.3Å; T179-H242 WeakPolarHBondContact CB-O 3.23Å; H181-H242 AromaticContact CD2-CD2 3.41Å; H181-H242 PolarHBondContact CD2-CD2 3.33Å; H181-H242 VanDerWaalsContact CD2-CD2 3.41Å; H181-H242 AromaticContact CD2-NE2 3.3Å; H181-H242 PolarHBondContact CD2-NE2 2.92Å; H181-H242 VanDerWaalsContact CD2-NE2 3.3Å; H181-H242 PolarHBondContact CD2-O 2.98Å; H181-H242 AromaticContact CE1-NE2 3.98Å; H181-H242 AromaticContact NE2-CD2 3.5Å; H181-H242 PolarHBondContact NE2-CD2 2.96Å; H181-H242 AromaticContact NE2-CE1 3.82Å; H181-H242 AromaticContact NE2-NE2 2.91Å; H181-H242 PolarHBondContact NE2-NE2 2.77Å; Y240-H242 HydrophobicContact CE1-CB 3.93Å; Y240-H242 AromaticContact CZ-ND1 3.91Å; Y240-H242 PolarHBondContact OH-ND1 3.16Å; H242-F313 HydrophobicContact CB-CB 4.42Å; H242-F313 HydrophobicContact CB-CD1 4.28Å; H242-F313 WeakPolarHBondContact CB-O 3.26Å; H242-F313 PolarHBondContact CD2-O 3.01Å; H242-H314 AromaticContact CD2-CD2 3.73Å; H242-H314 AromaticContact CD2-NE2 3.69Å; H242-H314 AromaticContact NE2-CD2 3.66Å; H242-H314 AromaticContact NE2-CE1 3.95Å; H242-H314 AromaticContact NE2-NE2 3.15Å; H242-H314 PolarHBondContact NE2-NE2 3.01Å; H242-H314 VanDerWaalsContact NE2-NE2 3.15Å; H242-Y339 PolarHBondContact ND1-OH 2.96Å
243S98.7Very high96Very high7 Ų734.5 Ų34.55%0.04916%0.164CC..  trans-155.2170.917466.40000111.1F313 H314 H315S243-F313 WeakPolarHBondContact CB-O 3.23Å; S243-F313 PolarHBondContact OG-O 2.83Å; S243-H314 WeakPolarHBondContact OG-CA 3.12Å; S243-H315 PolarHBondContact O-CE1 2.86Å; S243-H315 PolarHBondContact OG-N 2.98Å; S243-H315 PolarHBondContact OG-ND1 2.84Å
244F98.8Very high96.3Very high1 Ų132.2 Ų32.20%0.00415%0.145CC..  trans-136.5166.9174.369.3-69.4000109.4H183 I193 I207 M246 F251 H315H183-F244 HydrophobicContact CB-CZ 4.28Å; H183-F244 AromaticContact CD2-CE1 3.81Å; H183-F244 AromaticContact CD2-CE2 3.69Å; H183-F244 AromaticContact CD2-CZ 3.55Å; H183-F244 PolarHBondContact NE2-O 3.43Å; I193-F244 HydrophobicContact CB-CD1 4Å; I193-F244 HydrophobicContact CB-CE1 4.44Å; I193-F244 HydrophobicContact CB-CG 4.28Å; I193-F244 HydrophobicContact CD1-CB 4.47Å; I193-F244 HydrophobicContact CG2-CB 4.14Å; I193-F244 HydrophobicContact CG2-CD1 3.59Å; I193-F244 HydrophobicContact CG2-CE1 4.31Å; I193-F244 HydrophobicContact CG2-CG 4.07Å; I207-F244 HydrophobicContact CD1-CD2 3.85Å; I207-F244 HydrophobicContact CD1-CE2 3.86Å; I207-F244 HydrophobicContact CD1-CG 4.39Å; I207-F244 HydrophobicContact CD1-CZ 4.43Å; F244-M246 HydrophobicContact CE2-CB 4.43Å; F244-F251 HydrophobicContact CD2-CD1 4.16Å; F244-F251 AromaticContact CE2-CD1 3.71Å; F244-F251 HydrophobicContact CE2-CD1 3.71Å; F244-F251 HydrophobicContact CE2-CE1 4.04Å; F244-H315 VanDerWaalsContact C-CE1 3.46Å; F244-H315 WeakPolarHBondContact CA-CE1 3.48Å
245G98.7Very high96.6Very high0 Ų030 Ų300%014%0.135CC..EExtended strand (participates in β ladder)trans-99.6144.2175.100000111.5F251 V252 H315 T318G245-F251 WeakPolarHBondContact O-CA 3.33Å; G245-V252 PolarHBondContact N-O 2.83Å; G245-V252 PolarHBondContact O-N 2.97Å; G245-H315 PolarHBondContact N-CD2 3.38Å; G245-H315 PolarHBondContact N-NE2 2.76Å; G245-T318 WeakPolarHBondContact CA-OG1 3.4Å
246M98.6Very high97.1Very high12 Ų1223.7 Ų23.76%0.05911%0.112CC..EExtended strand (participates in β ladder)trans-138.1129.2175.4-172.9-179.681.300110.2H183 E185 Y191 F244 F251 G429H183-M246 HydrophobicContact CB-CB 4.25Å; H183-M246 HydrophobicContact CB-CE 3.55Å; H183-M246 HydrophobicContact CB-SD 3.74Å; H183-M246 VanDerWaalsContact CD2-CB 3.43Å; H183-M246 WeakPolarHBondContact CD2-CB 3.41Å; H183-M246 PolarHBondContact NE2-N 2.68Å; E185-M246 HydrophobicContact CG-CE 4.11Å; Y191-M246 HydrophobicContact CD2-SD 3.78Å; Y191-M246 HydrophobicContact CE2-SD 4.43Å; Y191-M246 HydrophobicContact CG-SD 4.07Å; F244-M246 HydrophobicContact CE2-CB 4.43Å; M246-F251 HydrophobicContact CB-CD1 4.21Å; M246-F251 HydrophobicContact CB-CE1 4.43Å; M246-F251 HydrophobicContact CG-CD1 3.86Å; M246-F251 HydrophobicContact CG-CE1 3.7Å; M246-F251 HydrophobicContact SD-CD1 4.4Å; M246-F251 HydrophobicContact SD-CE1 3.7Å; M246-G429 WeakPolarHBondContact O-CA 3.37Å
247S98.2Very high97.5Very high2 Ų218 Ų181%0.0149%0.087CC..  trans-109.5-172.3168.457.40000109.9N249 Y250 E320S247-N249 VanDerWaalsContact C-N 3.31Å; S247-N249 PolarHBondContact O-N 2.79Å; S247-Y250 PolarHBondContact N-O 3.25Å; S247-Y250 WeakPolarHBondContact OG-CA 3.04Å; S247-Y250 WeakPolarHBondContact OG-CB 3.48Å; S247-Y250 PolarHBondContact OG-N 2.9Å; S247-Y250 PolarHBondContact OG-O 3.25Å; S247-E320 PolarHBondContact OG-OE1 3.44Å
248E96.3Very high97.7Very high134 Ų13415.5 Ų15.563%0.6268%0.076SC*.SBendtrans-58.8-43.8177-173.2167.9178.100111.8K295 E320E248-K295 WeakPolarHBondContact O-CD 3.5Å; E248-K295 PolarHBondContact O-NZ 2.72Å; E248-E320 PolarHBondContact N-OE1 3.25Å
249N98.1Very high97.8Very high78 Ų7815.4 Ų15.442%0.4178%0.076SC..SBendtrans-115.5-12-172.5-56.4-66000114.6S247 K294 K295 E320S247-N249 VanDerWaalsContact C-N 3.31Å; S247-N249 PolarHBondContact O-N 2.79Å; N249-K294 CarbonylContact O-C 3.47Å; N249-K294 WeakPolarHBondContact O-CA 3.14Å; N249-K295 WeakPolarHBondContact O-CB 3.19Å; N249-K295 PolarHBondContact O-N 3.15Å; N249-E320 VanDerWaalsContact CB-OE1 3.29Å; N249-E320 WeakPolarHBondContact CB-OE1 3.35Å; N249-E320 PolarHBondContact N-OE1 3.08Å; N249-E320 PolarHBondContact ND2-OE1 2.98Å; N249-E320 VanDerWaalsContact ND2-OE1 3.12Å; N249-E320 PolarHBondContact ND2-OE2 3.27Å
250Y98.6Very high97.7Very high35 Ų3516.6 Ų16.614%0.1378%0.082CC..EExtended strand (participates in β ladder)trans-132.7147.4-173.4-58.4-90.3000114.5S247 V292 A293 K294 I301 E320 I325 L373S247-Y250 PolarHBondContact N-O 3.25Å; S247-Y250 WeakPolarHBondContact OG-CA 3.04Å; S247-Y250 WeakPolarHBondContact OG-CB 3.48Å; S247-Y250 PolarHBondContact OG-N 2.9Å; S247-Y250 PolarHBondContact OG-O 3.25Å; Y250-V292 HydrophobicContact CD1-CG1 3.86Å; Y250-V292 HydrophobicContact CG-CG1 4.43Å; Y250-A293 CarbonylContact C-O 3.59Å; Y250-A293 VanDerWaalsContact CA-O 3.25Å; Y250-A293 WeakPolarHBondContact CA-O 3.47Å; Y250-K294 HydrophobicContact CD1-CG 4.1Å; Y250-K294 HydrophobicContact CE1-CG 3.65Å; Y250-I301 HydrophobicContact CD1-CD1 4.09Å; Y250-I301 HydrophobicContact CE1-CD1 3.81Å; Y250-E320 HydrophobicContact CD2-CG 3.95Å; Y250-E320 HydrophobicContact CE2-CG 4.3Å; Y250-E320 WeakPolarHBondContact CE2-OE2 3.31Å; Y250-I325 HydrophobicContact CD1-CD1 3.99Å; Y250-I325 HydrophobicContact CD2-CD1 4.03Å; Y250-I325 HydrophobicContact CD2-CG1 4.15Å; Y250-I325 HydrophobicContact CG-CD1 3.62Å; Y250-I325 HydrophobicContact CG-CG1 4.25Å; Y250-L373 HydrophobicContact CD1-CD2 4.23Å; Y250-L373 HydrophobicContact CE1-CD2 3.72Å; Y250-L373 HydrophobicContact CE2-CD1 3.71Å; Y250-L373 HydrophobicContact CE2-CD2 4.22Å
251F98.8Very high97.4Very high0 Ų016.7 Ų16.70%08%0.083CC..EExtended strand (participates in β ladder)trans-98.7140.2161.6-59.7-61.8000110.2Y191 I207 V227 V228 F230 F244 G245 M246 V292 A293 K295Y191-F251 AromaticContact CD1-CE1 3.85Å; Y191-F251 HydrophobicContact CD1-CE1 3.85Å; Y191-F251 HydrophobicContact CD1-CE2 4.5Å; Y191-F251 AromaticContact CD1-CZ 3.42Å; Y191-F251 HydrophobicContact CD1-CZ 3.42Å; Y191-F251 VanDerWaalsContact CD1-CZ 3.42Å; Y191-F251 HydrophobicContact CE1-CE1 4.31Å; Y191-F251 HydrophobicContact CE1-CE2 4.45Å; Y191-F251 AromaticContact CE1-CZ 3.53Å; Y191-F251 HydrophobicContact CE1-CZ 3.53Å; Y191-F251 HydrophobicContact CG-CE1 4.08Å; Y191-F251 HydrophobicContact CG-CZ 4.11Å; I207-F251 HydrophobicContact CG1-CD2 4.31Å; I207-F251 HydrophobicContact CG1-CG 4.38Å; I207-F251 HydrophobicContact CG2-CD2 4.29Å; I207-F251 HydrophobicContact CG2-CE1 4.19Å; I207-F251 HydrophobicContact CG2-CE2 3.87Å; I207-F251 HydrophobicContact CG2-CZ 3.83Å; V227-F251 HydrophobicContact CG1-CE2 4.12Å; V228-F251 HydrophobicContact CG1-CD2 4.02Å; V228-F251 HydrophobicContact CG1-CE2 4.44Å; F230-F251 HydrophobicContact CE2-CB 4.49Å; F230-F251 HydrophobicContact CZ-CB 4.05Å; F244-F251 HydrophobicContact CD2-CD1 4.16Å; F244-F251 AromaticContact CE2-CD1 3.71Å; F244-F251 HydrophobicContact CE2-CD1 3.71Å; F244-F251 HydrophobicContact CE2-CE1 4.04Å; G245-F251 WeakPolarHBondContact O-CA 3.33Å; M246-F251 HydrophobicContact CB-CD1 4.21Å; M246-F251 HydrophobicContact CB-CE1 4.43Å; M246-F251 HydrophobicContact CG-CD1 3.86Å; M246-F251 HydrophobicContact CG-CE1 3.7Å; M246-F251 HydrophobicContact SD-CD1 4.4Å; M246-F251 HydrophobicContact SD-CE1 3.7Å; F251-V292 WeakPolarHBondContact O-CA 3.33Å; F251-A293 PolarHBondContact N-O 3.3Å; F251-A293 PolarHBondContact O-N 3.5Å; F251-K295 HydrophobicContact CD2-CB 4.33Å; F251-K295 HydrophobicContact CE1-CD 4.48Å; F251-K295 HydrophobicContact CE1-CG 4.43Å; F251-K295 HydrophobicContact CE2-CB 3.83Å; F251-K295 HydrophobicContact CE2-CG 3.81Å; F251-K295 HydrophobicContact CZ-CB 4.07Å; F251-K295 HydrophobicContact CZ-CD 4.09Å; F251-K295 HydrophobicContact CZ-CG 3.63Å
252V98.7Very high96.7Very high0 Ų018.6 Ų18.60%09%0.093CC..EExtended strand (participates in β ladder)trans-119.7123.7171.9179.70000108.5G245 H291 T318 I325 F327G245-V252 PolarHBondContact N-O 2.83Å; G245-V252 PolarHBondContact O-N 2.97Å; V252-H291 WeakPolarHBondContact CA-O 3.48Å; V252-T318 HydrophobicContact CG2-CG2 3.89Å; V252-I325 HydrophobicContact CG2-CD1 4.39Å; V252-I325 HydrophobicContact CG2-CG2 3.71Å; V252-F327 HydrophobicContact CG1-CD1 4.22Å; V252-F327 HydrophobicContact CG1-CD2 4.35Å; V252-F327 HydrophobicContact CG1-CE1 4.18Å; V252-F327 HydrophobicContact CG1-CE2 4.3Å; V252-F327 HydrophobicContact CG1-CG 4.3Å; V252-F327 HydrophobicContact CG1-CZ 4.21Å
253F98.5Very high95.9Very high0 Ų024 Ų240%012%0.121CC..EExtended strand (participates in β ladder)trans-118.5128.5174.3164.3-123.3000109.9I193 Y205 F230 V241 E255 H291I193-F253 HydrophobicContact CD1-CB 4.11Å; I193-F253 HydrophobicContact CD1-CD1 4.49Å; I193-F253 HydrophobicContact CD1-CD2 3.72Å; I193-F253 HydrophobicContact CD1-CE2 4.35Å; I193-F253 HydrophobicContact CD1-CG 3.83Å; Y205-F253 HydrophobicContact CD1-CE1 4.32Å; Y205-F253 HydrophobicContact CD1-CZ 4.04Å; Y205-F253 HydrophobicContact CD2-CD1 4.16Å; Y205-F253 AromaticContact CD2-CE1 3.38Å; Y205-F253 HydrophobicContact CD2-CE1 3.38Å; Y205-F253 AromaticContact CD2-CZ 3.9Å; Y205-F253 HydrophobicContact CD2-CZ 3.9Å; Y205-F253 HydrophobicContact CE1-CE1 4.37Å; Y205-F253 AromaticContact CE1-CZ 3.92Å; Y205-F253 HydrophobicContact CE1-CZ 3.92Å; Y205-F253 AromaticContact CE2-CE1 3.42Å; Y205-F253 HydrophobicContact CE2-CE1 3.42Å; Y205-F253 VanDerWaalsContact CE2-CE1 3.42Å; Y205-F253 AromaticContact CE2-CZ 3.77Å; Y205-F253 HydrophobicContact CE2-CZ 3.77Å; Y205-F253 AromaticContact CG-CE1 3.85Å; Y205-F253 HydrophobicContact CG-CE1 3.85Å; Y205-F253 HydrophobicContact CG-CZ 4.03Å; Y205-F253 AromaticContact CZ-CE1 3.95Å; Y205-F253 AromaticContact CZ-CZ 3.79Å; F230-F253 HydrophobicContact CB-CD1 4.01Å; F230-F253 HydrophobicContact CD2-CB 3.94Å; F230-F253 HydrophobicContact CD2-CD1 4.17Å; F230-F253 HydrophobicContact CD2-CG 4.32Å; F230-F253 HydrophobicContact CE2-CB 3.81Å; F230-F253 HydrophobicContact CG-CB 4.35Å; F230-F253 HydrophobicContact CG-CD1 4.05Å; F230-F253 HydrophobicContact CZ-CB 4.12Å; V241-F253 HydrophobicContact CB-CE2 4.25Å; V241-F253 HydrophobicContact CG1-CD2 4.17Å; V241-F253 HydrophobicContact CG1-CE2 3.79Å; V241-F253 HydrophobicContact CG2-CE2 3.46Å; V241-F253 VanDerWaalsContact CG2-CE2 3.46Å; V241-F253 HydrophobicContact CG2-CZ 3.76Å; F253-E255 HydrophobicContact CE1-CB 3.74Å; F253-E255 HydrophobicContact CE1-CG 4.26Å; F253-E255 HydrophobicContact CZ-CB 3.75Å; F253-E255 HydrophobicContact CZ-CG 4.12Å; F253-H291 HydrophobicContact CB-CB 4.22Å; F253-H291 HydrophobicContact CD1-CB 4.1Å; F253-H291 AromaticContact CD1-CD2 3.39Å; F253-H291 WeakPolarHBondContact CD1-CD2 3.04Å; F253-H291 AromaticContact CD1-CG 3.98Å; F253-H291 AromaticContact CE1-CD2 3.66Å; F253-H291 PolarHBondContact N-O 3.18Å; F253-H291 PolarHBondContact O-N 2.64Å
254V98.5Very high95.1Very high3 Ų327.6 Ų27.62%0.01814%0.136CC..EExtended strand (participates in β ladder)trans-104104.3-179.5-174.90000109T256 T288 F290 M312 F327 L329V254-T256 PolarHBondContact O-N 2.8Å; V254-T288 HydrophobicContact CG1-CG2 3.43Å; V254-T288 VanDerWaalsContact CG1-CG2 3.43Å; V254-F290 HydrophobicContact CB-CD1 4.45Å; V254-F290 HydrophobicContact CG1-CD1 4.02Å; V254-F290 HydrophobicContact CG1-CE1 3.88Å; V254-F290 HydrophobicContact CG2-CD1 3.96Å; V254-F290 HydrophobicContact CG2-CE1 4.3Å; V254-M312 HydrophobicContact CB-CE 3.47Å; V254-M312 VanDerWaalsContact CB-CE 3.47Å; V254-M312 HydrophobicContact CG1-CE 4.03Å; V254-M312 HydrophobicContact CG2-CE 3.74Å; V254-F327 HydrophobicContact CG2-CE2 4.21Å; V254-L329 HydrophobicContact CG2-CD1 4.18Å
255E98.3Very high94.1Very high0 Ų029.6 Ų29.60%015%0.145CC..EExtended strand (participates in β ladder)trans-83.2102.6177-170.3178.4-160.200109.8Y205 A233 S239 F253 K259 I289 H291Y205-E255 PolarHBondContact OH-OE1 2.91Å; A233-E255 WeakPolarHBondContact CB-OE2 3.31Å; A233-E255 PolarHBondContact N-OE1 3.35Å; A233-E255 PolarHBondContact N-OE2 2.78Å; A233-E255 VanDerWaalsContact N-OE2 3.12Å; S239-E255 WeakPolarHBondContact OG-CG 3.47Å; F253-E255 HydrophobicContact CE1-CB 3.74Å; F253-E255 HydrophobicContact CE1-CG 4.26Å; F253-E255 HydrophobicContact CZ-CB 3.75Å; F253-E255 HydrophobicContact CZ-CG 4.12Å; E255-K259 IonicContact OE1-NZ 3.79Å; E255-K259 PolarHBondContact OE1-NZ 2.8Å; E255-I289 HydrophobicContact CB-CB 4.21Å; E255-I289 PolarHBondContact N-O 3.3Å; E255-I289 PolarHBondContact O-N 3.05Å; E255-H291 IonicContact OE2-CE1 3.24Å; E255-H291 IonicContact OE2-NE2 3.87Å; E255-H291 PolarHBondContact OE2-NE2 2.91Å
256T97.9Very high93Very high5 Ų535.1 Ų35.13%0.03117%0.174CC..  trans-78163.4-178.6710000111.9S239 V254 V258 Q286 M312S239-T256 WeakPolarHBondContact CB-O 3.42Å; S239-T256 PolarHBondContact OG-O 2.73Å; V254-T256 PolarHBondContact O-N 2.8Å; T256-V258 PolarHBondContact O-N 2.96Å; T256-Q286 PolarHBondContact O-NE2 3.37Å; T256-M312 HydrophobicContact CG2-CB 4.37Å
257P97.3Very high91.7Very high0 Ų037.4 Ų37.40%019%0.191CC..SBendtrans-73.9-3.2175.230.6-36.9000114K259 S282 N283 P309 I310 F335P257-K259 PolarHBondContact O-N 2.84Å; P257-S282 WeakPolarHBondContact O-CA 3.35Å; P257-N283 VanDerWaalsContact CB-O 3.27Å; P257-N283 WeakPolarHBondContact CB-O 3.43Å; P257-N283 PolarHBondContact O-N 3.03Å; P257-P309 HydrophobicContact CG-CB 4.14Å; P257-I310 VanDerWaalsContact CD-O 3.31Å; P257-I310 WeakPolarHBondContact CD-O 3.39Å; P257-F335 HydrophobicContact CB-CB 3.93Å; P257-F335 HydrophobicContact CG-CB 3.59Å
258V97.1Very high90.1Very high4 Ų437.8 Ų37.82%0.02419%0.194CC..EExtended strand (participates in β ladder)trans-80.6114.7176.2178.20000108.8S239 Y240 T256 F280 F337S239-V258 CarbonylContact C-O 3.5Å; S239-V258 WeakPolarHBondContact CA-O 3.4Å; S239-V258 WeakPolarHBondContact CB-O 3.42Å; Y240-V258 PolarHBondContact N-O 2.83Å; T256-V258 PolarHBondContact O-N 2.96Å; V258-F280 HydrophobicContact CG1-CD1 3.8Å; V258-F337 HydrophobicContact CB-CD2 4.45Å; V258-F337 HydrophobicContact CG1-CB 4.12Å; V258-F337 HydrophobicContact CG1-CD1 4.21Å; V258-F337 HydrophobicContact CG1-CD2 3.67Å; V258-F337 HydrophobicContact CG1-CE2 4.03Å; V258-F337 HydrophobicContact CG1-CG 3.76Å; V258-F337 HydrophobicContact CG1-CZ 4.43Å; V258-F337 HydrophobicContact CG2-CB 4.17Å; V258-F337 HydrophobicContact CG2-CD2 4.05Å; V258-F337 HydrophobicContact CG2-CG 4.39Å
259K95.8Very high88.5Confident1 Ų134.7 Ų34.70%0.00418%0.177CC..EExtended strand (participates in β ladder)trans-111.6147.8-171.8-65.4-54-169.1175.10112.4E234 K237 P238 S239 E255 P257 F280 E281 N283E234-K259 WeakPolarHBondContact OE1-CE 3.35Å; K237-K259 HydrophobicContact CB-CB 4.2Å; K237-K259 HydrophobicContact CB-CD 4.47Å; K237-K259 HydrophobicContact CB-CG 4.45Å; P238-K259 CarbonylContact O-C 3.5Å; P238-K259 WeakPolarHBondContact O-CA 3.41Å; S239-K259 WeakPolarHBondContact OG-CD 3.38Å; S239-K259 WeakPolarHBondContact OG-CE 3.43Å; S239-K259 PolarHBondContact OG-NZ 2.95Å; E255-K259 IonicContact OE1-NZ 3.79Å; E255-K259 PolarHBondContact OE1-NZ 2.8Å; P257-K259 PolarHBondContact O-N 2.84Å; K259-F280 CarbonylContact O-C 3.55Å; K259-F280 VanDerWaalsContact O-CA 3.27Å; K259-F280 WeakPolarHBondContact O-CA 3.36Å; K259-E281 HydrophobicContact CB-CG 4.17Å; K259-E281 PolarHBondContact N-O 2.76Å; K259-E281 PolarHBondContact O-N 2.91Å; K259-N283 HydrophobicContact CG-CB 4.28Å
260I92.8Very high86.6Confident25 Ų2535.1 Ų35.113%0.12819%0.186CC..EExtended strand (participates in β ladder)trans-99114.4171-57.7166.5000108.4K237 P238 L262 F280K237-I260 WeakPolarHBondContact CA-O 3.33Å; P238-I260 VanDerWaalsContact CD-O 3.26Å; P238-I260 WeakPolarHBondContact CD-O 3.47Å; P238-I260 HydrophobicContact CG-CB 4.27Å; P238-I260 PolarHBondContact O-N 3.25Å; I260-L262 HydrophobicContact CG2-CD2 4.01Å; I260-L262 PolarHBondContact O-N 2.99Å; I260-F280 HydrophobicContact CD1-CE1 4.07Å; I260-F280 HydrophobicContact CD1-CZ 4.38Å; I260-F280 HydrophobicContact CG1-CD1 3.91Å; I260-F280 HydrophobicContact CG1-CE1 3.47Å; I260-F280 VanDerWaalsContact CG1-CE1 3.47Å; I260-F280 HydrophobicContact CG1-CZ 4.04Å
261N90.4Very high84.6Confident18 Ų1839.8 Ų39.810%0.09621%0.212CC..  trans-82.993177.5-170.7-31.4000110.5L263 K264 F265 C279 E281N261-L263 PolarHBondContact O-N 2.98Å; N261-L263 PolarHBondContact OD1-N 3.06Å; N261-K264 HydrophobicContact CB-CB 4.16Å; N261-K264 HydrophobicContact CB-CD 4Å; N261-K264 HydrophobicContact CB-CG 4.13Å; N261-K264 WeakPolarHBondContact O-CB 3.49Å; N261-K264 PolarHBondContact O-N 3.08Å; N261-K264 VanDerWaalsContact O-N 3.08Å; N261-K264 PolarHBondContact OD1-N 3Å; N261-K264 VanDerWaalsContact OD1-N 3.14Å; N261-F265 PolarHBondContact O-N 3.49Å; N261-C279 WeakPolarHBondContact CB-O 3.31Å; N261-C279 PolarHBondContact N-O 3.11Å; N261-E281 HydrophobicContact CB-CG 4.38Å; N261-E281 PolarHBondContact ND2-OE1 3.01Å; N261-E281 PolarHBondContact ND2-OE2 3.04Å
262L81.7Confident82.8Confident54 Ų5449.3 Ų49.328%0.28325%0.248SC..Hα-helixtrans-62.7-26.2-178.4-66.8-171000113.8L203 I260 F265 L266L203-L262 HydrophobicContact CD1-CD1 3.4Å; L203-L262 HydrophobicContact CD1-CG 4.15Å; L203-L262 HydrophobicContact CD2-CD1 3.79Å; L203-L262 HydrophobicContact CG-CD1 4.2Å; I260-L262 HydrophobicContact CG2-CD2 4.01Å; I260-L262 PolarHBondContact O-N 2.99Å; L262-F265 WeakPolarHBondContact O-CB 3.42Å; L262-F265 PolarHBondContact O-N 2.81Å; L262-L266 WeakPolarHBondContact O-CG 3.4Å; L262-L266 PolarHBondContact O-N 2.95Å
263L81.5Confident81.5Confident124 Ų12451.8 Ų51.865%0.64927%0.273SS*.Hα-helixtrans-68.7-39.2175.1-66.4174.5000111N261 S267N261-L263 PolarHBondContact O-N 2.98Å; N261-L263 PolarHBondContact OD1-N 3.06Å; L263-S267 WeakPolarHBondContact O-CB 3.47Å; L263-S267 PolarHBondContact O-N 3.06Å; L263-S267 PolarHBondContact O-OG 3.37Å
264K83.4Confident80.7Confident84 Ų8452.6 Ų52.637%0.36528%0.279SS..Hα-helixtrans-62.1-46.5169.5-73.3-179.1-176.7163.10110.4N261 L266 S267 A268 E281N261-K264 HydrophobicContact CB-CB 4.16Å; N261-K264 HydrophobicContact CB-CD 4Å; N261-K264 HydrophobicContact CB-CG 4.13Å; N261-K264 WeakPolarHBondContact O-CB 3.49Å; N261-K264 PolarHBondContact O-N 3.08Å; N261-K264 VanDerWaalsContact O-N 3.08Å; N261-K264 PolarHBondContact OD1-N 3Å; N261-K264 VanDerWaalsContact OD1-N 3.14Å; K264-L266 PolarHBondContact O-N 3.09Å; K264-S267 PolarHBondContact O-N 3.22Å; K264-S267 PolarHBondContact O-OG 2.94Å; K264-A268 WeakPolarHBondContact O-CB 3.3Å; K264-A268 PolarHBondContact O-N 2.91Å; K264-E281 IonicContact NZ-OE2 3.54Å; K264-E281 PolarHBondContact NZ-OE2 2.97Å; K264-E281 VanDerWaalsContact NZ-OE2 3.15Å
265F77Confident80.2Confident43 Ų4353.1 Ų53.119%0.18928%0.282CS..Hα-helixtrans-55.6-49.2177.8-170.9-98.8000112.3N261 L262 W269 Y276 C279N261-F265 PolarHBondContact O-N 3.49Å; L262-F265 WeakPolarHBondContact O-CB 3.42Å; L262-F265 PolarHBondContact O-N 2.81Å; F265-W269 HydrophobicContact CD2-CE3 4.18Å; F265-W269 AromaticContact CD2-CH2 3.5Å; F265-W269 HydrophobicContact CD2-CH2 3.5Å; F265-W269 HydrophobicContact CD2-CZ2 4.2Å; F265-W269 AromaticContact CD2-CZ3 3.5Å; F265-W269 HydrophobicContact CD2-CZ3 3.5Å; F265-W269 HydrophobicContact CE2-CE3 4.4Å; F265-W269 AromaticContact CE2-CH2 3.27Å; F265-W269 HydrophobicContact CE2-CH2 3.27Å; F265-W269 AromaticContact CE2-CZ2 3.57Å; F265-W269 HydrophobicContact CE2-CZ2 3.57Å; F265-W269 AromaticContact CE2-CZ3 3.75Å; F265-W269 HydrophobicContact CE2-CZ3 3.75Å; F265-W269 HydrophobicContact CG-CE3 4.45Å; F265-W269 HydrophobicContact CG-CH2 4.49Å; F265-W269 HydrophobicContact CG-CZ3 4.16Å; F265-W269 HydrophobicContact CZ-CH2 4.12Å; F265-W269 AromaticContact CZ-CZ2 3.99Å; F265-W269 HydrophobicContact CZ-CZ2 3.99Å; F265-W269 PolarHBondContact O-N 3.17Å; F265-Y276 AromaticContact CE2-CD1 3.84Å; F265-Y276 HydrophobicContact CE2-CD1 3.84Å; F265-Y276 AromaticContact CE2-CE1 3.79Å; F265-Y276 HydrophobicContact CE2-CE1 3.79Å; F265-Y276 HydrophobicContact CZ-CE1 4.27Å; F265-C279 VanDerWaalsContact CA-SG 3.55Å; F265-C279 HydrophobicContact CB-CB 4.47Å
266L75.3Confident79.8Confident116 Ų11654.8 Ų54.861%0.60729%0.288SS*.Hα-helixtrans-72.7-36.6-179.3-65.2172.2000113.5L262 K264 S270L262-L266 WeakPolarHBondContact O-CG 3.4Å; L262-L266 PolarHBondContact O-N 2.95Å; K264-L266 PolarHBondContact O-N 3.09Å; L266-S270 PolarHBondContact O-OG 2.93Å; L266-S270 VanDerWaalsContact O-OG 3.08Å
267S71.6Confident79.6Confident59 Ų5955.1 Ų55.141%0.41329%0.289SS..Hα-helixtrans-78.8-33.5-178.262.80000113.6L263 K264 S270 I271L263-S267 WeakPolarHBondContact O-CB 3.47Å; L263-S267 PolarHBondContact O-N 3.06Å; L263-S267 PolarHBondContact O-OG 3.37Å; K264-S267 PolarHBondContact O-N 3.22Å; K264-S267 PolarHBondContact O-OG 2.94Å; S267-S270 PolarHBondContact O-N 3.47Å; S267-S270 PolarHBondContact O-OG 2.85Å; S267-I271 PolarHBondContact O-N 3.3Å; S267-I271 VanDerWaalsContact O-N 3.16Å
268A64.8Low79.3Confident10 Ų1058.9 Ų58.98%0.08331%0.309CS..Hα-helixtrans-58.9-54.6172.400000110K264 S270 I271 R272K264-A268 WeakPolarHBondContact O-CB 3.3Å; K264-A268 PolarHBondContact O-N 2.91Å; A268-S270 PolarHBondContact O-N 2.86Å; A268-I271 PolarHBondContact O-N 2.92Å; A268-I271 VanDerWaalsContact O-N 3.08Å; A268-R272 CarbonylContact C-O 3.53Å; A268-R272 WeakPolarHBondContact CA-O 3.47Å; A268-R272 CarbonylContact O-C 3.54Å; A268-R272 VanDerWaalsContact O-C 3.3Å; A268-R272 PolarHBondContact O-N 3.49Å
269W61.8Low79Confident70 Ų7058.7 Ų58.727%0.26531%0.309SS..Hα-helixtrans-58.6-23.9-175.8-90.8-108000114.3V127 F265V127-W269 HydrophobicContact CG1-CG 4.3Å; V127-W269 HydrophobicContact CG2-CB 4.25Å; V127-W269 VanDerWaalsContact CG2-CD1 3.46Å; V127-W269 HydrophobicContact CG2-CG 4Å; F265-W269 HydrophobicContact CD2-CE3 4.18Å; F265-W269 AromaticContact CD2-CH2 3.5Å; F265-W269 HydrophobicContact CD2-CH2 3.5Å; F265-W269 HydrophobicContact CD2-CZ2 4.2Å; F265-W269 AromaticContact CD2-CZ3 3.5Å; F265-W269 HydrophobicContact CD2-CZ3 3.5Å; F265-W269 HydrophobicContact CE2-CE3 4.4Å; F265-W269 AromaticContact CE2-CH2 3.27Å; F265-W269 HydrophobicContact CE2-CH2 3.27Å; F265-W269 AromaticContact CE2-CZ2 3.57Å; F265-W269 HydrophobicContact CE2-CZ2 3.57Å; F265-W269 AromaticContact CE2-CZ3 3.75Å; F265-W269 HydrophobicContact CE2-CZ3 3.75Å; F265-W269 HydrophobicContact CG-CE3 4.45Å; F265-W269 HydrophobicContact CG-CH2 4.49Å; F265-W269 HydrophobicContact CG-CZ3 4.16Å; F265-W269 HydrophobicContact CZ-CH2 4.12Å; F265-W269 AromaticContact CZ-CZ2 3.99Å; F265-W269 HydrophobicContact CZ-CZ2 3.99Å; F265-W269 PolarHBondContact O-N 3.17Å
270S58.5Low78.9Confident87 Ų8760.1 Ų60.161%0.60832%0.315SS*.Hα-helixtrans-95-23.7179.947.70000114.8L266 S267 A268L266-S270 PolarHBondContact O-OG 2.93Å; L266-S270 VanDerWaalsContact O-OG 3.08Å; S267-S270 PolarHBondContact O-N 3.47Å; S267-S270 PolarHBondContact O-OG 2.85Å; A268-S270 PolarHBondContact O-N 2.86Å
271I57.7Low79.1Confident133 Ų13361.3 Ų61.368%0.68232%0.32SS*.Hα-helixtrans-132.4-36.4-168.9-53.4176.2000113.5S267 A268S267-I271 PolarHBondContact O-N 3.3Å; S267-I271 VanDerWaalsContact O-N 3.16Å; A268-I271 PolarHBondContact O-N 2.92Å; A268-I271 VanDerWaalsContact O-N 3.08Å
272R60.9Low79.3Confident200 Ų20062.5 Ų62.576%0.75533%0.33SS*.SBendtrans-133124.7-173-71.4-175.8176.4177.1-1.1110.8A268 S274A268-R272 CarbonylContact C-O 3.53Å; A268-R272 WeakPolarHBondContact CA-O 3.47Å; A268-R272 CarbonylContact O-C 3.54Å; A268-R272 VanDerWaalsContact O-C 3.3Å; A268-R272 PolarHBondContact O-N 3.49Å; R272-S274 PolarHBondContact O-N 2.88Å
273G70.1Confident80Confident52 Ų5261.7 Ų61.754%0.53633%0.325SS..  trans-55.3125.4170.200000111.1
274S82.6Confident80.6Confident17 Ų1762.6 Ų62.612%0.11933%0.326CS..  trans-154.9157.3-172.7-154.90000110.1F106 R272 D278F106-S274 VanDerWaalsContact CD2-N 3.27Å; F106-S274 WeakPolarHBondContact CD2-O 3.44Å; R272-S274 PolarHBondContact O-N 2.88Å; S274-D278 WeakPolarHBondContact CA-OD2 3.3Å; S274-D278 WeakPolarHBondContact CB-OD2 3.35Å; S274-D278 WeakPolarHBondContact OG-CB 3.44Å; S274-D278 VanDerWaalsContact OG-CG 3.29Å; S274-D278 PolarHBondContact OG-OD2 2.81Å
275N87.8Confident81.1Confident14 Ų1463.8 Ų63.88%0.07535%0.345CS..  trans-111.1-176.2177.559.747.2000111.3T101 F103 G104 M277 D278T101-N275 HydrophobicContact CG2-CB 4.13Å; F103-N275 WeakPolarHBondContact O-CB 3.38Å; G104-N275 PolarHBondContact O-ND2 3.34Å; N275-M277 WeakPolarHBondContact OD1-CA 3.13Å; N275-M277 VanDerWaalsContact OD1-CB 3.27Å; N275-M277 WeakPolarHBondContact OD1-CB 3.29Å; N275-M277 PolarHBondContact OD1-N 3.27Å; N275-D278 PolarHBondContact N-OD2 3.1Å; N275-D278 VanDerWaalsContact OD1-CG 3.29Å; N275-D278 PolarHBondContact OD1-N 2.84Å; N275-D278 PolarHBondContact OD1-OD2 2.92Å
276Y90.3Very high82Confident34 Ų3462.5 Ų62.513%0.13334%0.34CS..SBendtrans-68.2-38.3178.4-59.9-94.9000111.5T101 E102 F103 T130 F265 D278 C279 F280T101-Y276 HydrophobicContact CG2-CD2 4.48Å; T101-Y276 HydrophobicContact CG2-CE2 4.26Å; E102-Y276 VanDerWaalsContact O-CD2 3.25Å; E102-Y276 WeakPolarHBondContact O-CD2 3.12Å; F103-Y276 PolarHBondContact O-N 3.22Å; T130-Y276 HydrophobicContact CG2-CE2 4.15Å; T130-Y276 PolarHBondContact N-OH 3.27Å; F265-Y276 AromaticContact CE2-CD1 3.84Å; F265-Y276 HydrophobicContact CE2-CD1 3.84Å; F265-Y276 AromaticContact CE2-CE1 3.79Å; F265-Y276 HydrophobicContact CE2-CE1 3.79Å; F265-Y276 HydrophobicContact CZ-CE1 4.27Å; Y276-D278 VanDerWaalsContact C-N 3.28Å; Y276-D278 PolarHBondContact O-N 3.43Å; Y276-C279 VanDerWaalsContact O-CB 3.29Å; Y276-C279 WeakPolarHBondContact O-CB 3.38Å; Y276-C279 PolarHBondContact O-N 3.34Å; Y276-F280 WeakPolarHBondContact O-CD2 3.4Å; Y276-F280 WeakPolarHBondContact O-CE2 3.47Å
277M93.3Very high83Confident13 Ų1357.5 Ų57.56%0.06432%0.316CS..G310 helixtrans-55.5-40.7-180-167.162.8-177.800112.6F103 N275 C279 F280 F337 N340 W343F103-M277 HydrophobicContact CE1-CB 4.12Å; F103-M277 HydrophobicContact CE1-CG 4.27Å; F103-M277 HydrophobicContact CE1-SD 3.45Å; F103-M277 WeakPolarHBondContact CE1-SD 3.34Å; F103-M277 HydrophobicContact CZ-CB 4.34Å; F103-M277 HydrophobicContact CZ-SD 3.46Å; F103-M277 WeakPolarHBondContact CZ-SD 3.39Å; F103-M277 PolarHBondContact O-N 2.93Å; N275-M277 WeakPolarHBondContact OD1-CA 3.13Å; N275-M277 VanDerWaalsContact OD1-CB 3.27Å; N275-M277 WeakPolarHBondContact OD1-CB 3.29Å; N275-M277 PolarHBondContact OD1-N 3.27Å; M277-C279 PolarHBondContact O-N 2.83Å; M277-C279 VanDerWaalsContact O-N 3.11Å; M277-F280 PolarHBondContact O-N 2.98Å; M277-F280 VanDerWaalsContact O-N 3.09Å; M277-F280 HydrophobicContact SD-CD2 4.5Å; M277-F337 HydrophobicContact CE-CD1 3.69Å; M277-F337 HydrophobicContact CE-CE1 4.07Å; M277-F337 HydrophobicContact SD-CD1 3.92Å; M277-F337 HydrophobicContact SD-CE1 3.72Å; M277-N340 HydrophobicContact CE-CB 4.35Å; M277-N340 WeakPolarHBondContact CE-OD1 3.42Å; M277-W343 HydrophobicContact CB-CH2 4.48Å; M277-W343 HydrophobicContact CG-CH2 4.33Å; M277-W343 HydrophobicContact CG-CZ2 3.94Å
278D90.6Very high84.3Confident78 Ų7854.7 Ų54.742%0.41730%0.297SS..G310 helixtrans-61.8-19.9177.9-62.8-34.9000113.9S274 N275 Y276S274-D278 WeakPolarHBondContact CA-OD2 3.3Å; S274-D278 WeakPolarHBondContact CB-OD2 3.35Å; S274-D278 WeakPolarHBondContact OG-CB 3.44Å; S274-D278 VanDerWaalsContact OG-CG 3.29Å; S274-D278 PolarHBondContact OG-OD2 2.81Å; N275-D278 PolarHBondContact N-OD2 3.1Å; N275-D278 VanDerWaalsContact OD1-CG 3.29Å; N275-D278 PolarHBondContact OD1-N 2.84Å; N275-D278 PolarHBondContact OD1-OD2 2.92Å; Y276-D278 VanDerWaalsContact C-N 3.28Å; Y276-D278 PolarHBondContact O-N 3.43Å
279C91.4Very high85.9Confident1 Ų155.1 Ų55.11%0.00730%0.297CS..G310 helixtrans-86.9-11.9-179.3-58.70000112.5N261 F265 Y276 M277N261-C279 WeakPolarHBondContact CB-O 3.31Å; N261-C279 PolarHBondContact N-O 3.11Å; F265-C279 VanDerWaalsContact CA-SG 3.55Å; F265-C279 HydrophobicContact CB-CB 4.47Å; Y276-C279 VanDerWaalsContact O-CB 3.29Å; Y276-C279 WeakPolarHBondContact O-CB 3.38Å; Y276-C279 PolarHBondContact O-N 3.34Å; M277-C279 PolarHBondContact O-N 2.83Å; M277-C279 VanDerWaalsContact O-N 3.11Å
280F94.6Very high87.6Confident30 Ų3051.8 Ų51.813%0.13229%0.285CS..EExtended strand (participates in β ladder)trans-81.5144.8177.9-68.5-89.9000112.2F103 Y240 V258 K259 I260 Y276 M277 F337F103-F280 HydrophobicContact CE2-CD2 4.49Å; F103-F280 AromaticContact CE2-CE2 3.61Å; F103-F280 HydrophobicContact CE2-CE2 3.61Å; F103-F280 HydrophobicContact CE2-CZ 4.12Å; F103-F280 HydrophobicContact CZ-CD2 4.46Å; F103-F280 AromaticContact CZ-CE2 3.97Å; F103-F280 HydrophobicContact CZ-CE2 3.97Å; Y240-F280 AromaticContact CD2-CE1 3.73Å; Y240-F280 HydrophobicContact CD2-CE1 3.73Å; Y240-F280 HydrophobicContact CD2-CZ 4.01Å; Y240-F280 AromaticContact CG-CE1 3.91Å; Y240-F280 HydrophobicContact CG-CE1 3.91Å; V258-F280 HydrophobicContact CG1-CD1 3.8Å; K259-F280 CarbonylContact O-C 3.55Å; K259-F280 VanDerWaalsContact O-CA 3.27Å; K259-F280 WeakPolarHBondContact O-CA 3.36Å; I260-F280 HydrophobicContact CD1-CE1 4.07Å; I260-F280 HydrophobicContact CD1-CZ 4.38Å; I260-F280 HydrophobicContact CG1-CD1 3.91Å; I260-F280 HydrophobicContact CG1-CE1 3.47Å; I260-F280 VanDerWaalsContact CG1-CE1 3.47Å; I260-F280 HydrophobicContact CG1-CZ 4.04Å; Y276-F280 WeakPolarHBondContact O-CD2 3.4Å; Y276-F280 WeakPolarHBondContact O-CE2 3.47Å; M277-F280 PolarHBondContact O-N 2.98Å; M277-F280 VanDerWaalsContact O-N 3.09Å; M277-F280 HydrophobicContact SD-CD2 4.5Å; F280-F337 HydrophobicContact CB-CD1 3.85Å; F280-F337 HydrophobicContact CB-CE1 4.02Å; F280-F337 HydrophobicContact CD1-CD1 4.23Å; F280-F337 AromaticContact CD1-CE1 3.74Å; F280-F337 HydrophobicContact CD1-CE1 3.74Å; F280-F337 HydrophobicContact CD1-CZ 4.14Å; F280-F337 HydrophobicContact CD2-CD1 4.45Å; F280-F337 AromaticContact CD2-CE1 3.79Å; F280-F337 HydrophobicContact CD2-CE1 3.79Å; F280-F337 HydrophobicContact CE1-CE1 4.09Å; F280-F337 HydrophobicContact CE1-CZ 4.12Å; F280-F337 HydrophobicContact CE2-CE1 4.15Å; F280-F337 AromaticContact CG-CD1 3.92Å; F280-F337 HydrophobicContact CG-CD1 3.92Å; F280-F337 AromaticContact CG-CE1 3.56Å; F280-F337 HydrophobicContact CG-CE1 3.56Å; F280-F337 HydrophobicContact CG-CZ 4.38Å; F280-F337 HydrophobicContact CZ-CE1 4.28Å; F280-F337 HydrophobicContact CZ-CZ 4.37Å
281E95.4Very high89.5Confident50 Ų5048 Ų4823%0.23426%0.258CS..EExtended strand (participates in β ladder)trans-149.3161171.860-170.4-14400110.4K237 K259 N261 K264K237-E281 VanDerWaalsContact CD-OE1 3.27Å; K237-E281 WeakPolarHBondContact CD-OE1 3.37Å; K237-E281 WeakPolarHBondContact CE-OE1 3.34Å; K237-E281 IonicContact NZ-OE1 3.06Å; K237-E281 PolarHBondContact NZ-OE1 3.44Å; K259-E281 HydrophobicContact CB-CG 4.17Å; K259-E281 PolarHBondContact N-O 2.76Å; K259-E281 PolarHBondContact O-N 2.91Å; N261-E281 HydrophobicContact CB-CG 4.38Å; N261-E281 PolarHBondContact ND2-OE1 3.01Å; N261-E281 PolarHBondContact ND2-OE2 3.04Å; K264-E281 IonicContact NZ-OE2 3.54Å; K264-E281 PolarHBondContact NZ-OE2 2.97Å; K264-E281 VanDerWaalsContact NZ-OE2 3.15Å
282S96.1Very high91.4Very high44 Ų4441.8 Ų41.831%0.30823%0.225SC..EExtended strand (participates in β ladder)trans-107.5130.5-180-61.60000110.9P257 F335P257-S282 WeakPolarHBondContact O-CA 3.35Å; S282-F335 VanDerWaalsContact CB-O 3.25Å; S282-F335 WeakPolarHBondContact CB-O 3.13Å; S282-F335 PolarHBondContact OG-O 3.46Å
283N96Very high93.2Very high36 Ų3632.2 Ų32.219%0.19319%0.189CC..  trans-90.6102.5169.5-174.6-26.5000110.3E234 P257 K259 S285 Q286E234-N283 PolarHBondContact OE1-ND2 3.13Å; P257-N283 VanDerWaalsContact CB-O 3.27Å; P257-N283 WeakPolarHBondContact CB-O 3.43Å; P257-N283 PolarHBondContact O-N 3.03Å; K259-N283 HydrophobicContact CG-CB 4.28Å; N283-S285 PolarHBondContact O-N 2.88Å; N283-S285 PolarHBondContact OD1-N 3Å; N283-S285 PolarHBondContact OD1-OG 2.83Å; N283-Q286 HydrophobicContact CB-CB 4.14Å; N283-Q286 PolarHBondContact OD1-N 2.89Å
284E94.3Very high94.5Very high144 Ų14433.3 Ų33.367%0.67318%0.179SC*.THydrogen-bonded Turntrans-64.3-23.6-176.5-56.4-174.1-17200113.9F335E284-F335 HydrophobicContact CB-CD1 4.49Å; E284-F335 HydrophobicContact CB-CE1 4.29Å; E284-F335 HydrophobicContact CB-CZ 4.37Å; E284-F335 HydrophobicContact CG-CD1 4.5Å; E284-F335 HydrophobicContact CG-CD2 4.12Å; E284-F335 HydrophobicContact CG-CE1 4.15Å; E284-F335 HydrophobicContact CG-CE2 3.74Å; E284-F335 HydrophobicContact CG-CG 4.48Å; E284-F335 HydrophobicContact CG-CZ 3.75Å
285S94.3Very high95.2Very high108 Ų10833.7 Ų33.776%0.75518%0.179SC*.THydrogen-bonded Turntrans-98.9-15.5-172.468.70000114.7N283 G287N283-S285 PolarHBondContact O-N 2.88Å; N283-S285 PolarHBondContact OD1-N 3Å; N283-S285 PolarHBondContact OD1-OG 2.83Å; S285-G287 PolarHBondContact O-N 3.46Å
286Q94.3Very high95.4Very high17 Ų1739.9 Ų39.98%0.07921%0.212CC..THydrogen-bonded Turntrans-69.3-35.7-173.5-174.2-177.7-86.700112.6T256 N283 I289T256-Q286 PolarHBondContact O-NE2 3.37Å; N283-Q286 HydrophobicContact CB-CB 4.14Å; N283-Q286 PolarHBondContact OD1-N 2.89Å; Q286-I289 HydrophobicContact CG-CD1 3.86Å; Q286-I289 HydrophobicContact CG-CG1 4.4Å
287G96.6Very high95.5Very high11 Ų1143.1 Ų43.111%0.11324%0.237CC..  trans65.1-153.4-160.500000111.1S285S285-G287 PolarHBondContact O-N 3.46Å
288T98.3Very high95.6Very high0 Ų043.4 Ų43.40%024%0.244CC..EExtended strand (participates in β ladder)trans-110.2136172.8-64.60000109.5V254 F290 K306 G307 A308 I310V254-T288 HydrophobicContact CG1-CG2 3.43Å; V254-T288 VanDerWaalsContact CG1-CG2 3.43Å; T288-F290 HydrophobicContact CG2-CD1 4.48Å; T288-F290 HydrophobicContact CG2-CE1 3.9Å; T288-F290 HydrophobicContact CG2-CE2 4Å; T288-F290 HydrophobicContact CG2-CZ 3.63Å; T288-K306 CarbonylContact O-C 3.54Å; T288-K306 VanDerWaalsContact O-CA 3.26Å; T288-K306 WeakPolarHBondContact O-CA 3.27Å; T288-G307 PolarHBondContact N-O 3.08Å; T288-G307 PolarHBondContact O-N 2.82Å; T288-A308 PolarHBondContact OG1-O 2.95Å; T288-I310 HydrophobicContact CG2-CD1 4.4Å; T288-I310 HydrophobicContact CG2-CG1 3.96Å; T288-I310 VanDerWaalsContact OG1-CG1 3.31Å; T288-I310 WeakPolarHBondContact OG1-CG1 3.46Å; T288-I310 PolarHBondContact OG1-N 2.94Å
289I98.3Very high95.9Very high19 Ų1944.4 Ų44.410%0.09725%0.246CC..EExtended strand (participates in β ladder)trans-111.3137.1177.9-58.6164.2000108.2A233 E255 Q286 H291 F305 K306A233-I289 HydrophobicContact CB-CD1 3.48Å; A233-I289 VanDerWaalsContact CB-CD1 3.48Å; E255-I289 HydrophobicContact CB-CB 4.21Å; E255-I289 PolarHBondContact N-O 3.3Å; E255-I289 PolarHBondContact O-N 3.05Å; Q286-I289 HydrophobicContact CG-CD1 3.86Å; Q286-I289 HydrophobicContact CG-CG1 4.4Å; I289-H291 WeakPolarHBondContact CG2-NE2 3.39Å; I289-F305 WeakPolarHBondContact CA-O 3.39Å; I289-K306 HydrophobicContact CG1-CD 4.33Å; I289-K306 HydrophobicContact CG1-CG 4.19Å
290F98.4Very high96.2Very high0 Ų047.1 Ų47.10%026%0.256CS..EExtended strand (participates in β ladder)trans-113.5118179.1-50.4-94.5000108.9V254 T288 F305 F327 Y369 I371 L404V254-F290 HydrophobicContact CB-CD1 4.45Å; V254-F290 HydrophobicContact CG1-CD1 4.02Å; V254-F290 HydrophobicContact CG1-CE1 3.88Å; V254-F290 HydrophobicContact CG2-CD1 3.96Å; V254-F290 HydrophobicContact CG2-CE1 4.3Å; T288-F290 HydrophobicContact CG2-CD1 4.48Å; T288-F290 HydrophobicContact CG2-CE1 3.9Å; T288-F290 HydrophobicContact CG2-CE2 4Å; T288-F290 HydrophobicContact CG2-CZ 3.63Å; F290-F305 HydrophobicContact CB-CB 3.85Å; F290-F305 HydrophobicContact CD2-CB 4.33Å; F290-F305 PolarHBondContact N-O 2.76Å; F290-F305 WeakPolarHBondContact O-CB 3.36Å; F290-F327 AromaticContact CD1-CE2 3.88Å; F290-F327 HydrophobicContact CD1-CE2 3.88Å; F290-F327 AromaticContact CD1-CZ 3.56Å; F290-F327 HydrophobicContact CD1-CZ 3.56Å; F290-F327 AromaticContact CE1-CE2 3.99Å; F290-F327 HydrophobicContact CE1-CE2 3.99Å; F290-F327 AromaticContact CE1-CZ 3.93Å; F290-F327 HydrophobicContact CE1-CZ 3.93Å; F290-F327 HydrophobicContact CG-CZ 4.37Å; F290-Y369 HydrophobicContact CE1-CD1 4.33Å; F290-Y369 HydrophobicContact CE1-CD2 4.35Å; F290-Y369 HydrophobicContact CE1-CE1 4.35Å; F290-Y369 HydrophobicContact CE1-CE2 4.38Å; F290-Y369 HydrophobicContact CE1-CG 4.32Å; F290-Y369 HydrophobicContact CE2-CE1 4.4Å; F290-Y369 HydrophobicContact CZ-CD1 4Å; F290-Y369 AromaticContact CZ-CE1 3.71Å; F290-Y369 HydrophobicContact CZ-CE1 3.71Å; F290-Y369 HydrophobicContact CZ-CE2 4.35Å; F290-Y369 HydrophobicContact CZ-CG 4.44Å; F290-Y369 AromaticContact CZ-CZ 3.9Å; F290-I371 HydrophobicContact CB-CD1 4.06Å; F290-L404 HydrophobicContact CB-CD1 4.37Å; F290-L404 HydrophobicContact CD2-CD1 3.61Å; F290-L404 HydrophobicContact CD2-CG 4.33Å; F290-L404 HydrophobicContact CE2-CB 4.34Å; F290-L404 HydrophobicContact CE2-CD1 3.95Å; F290-L404 HydrophobicContact CE2-CG 4.46Å; F290-L404 HydrophobicContact CG-CD1 3.93Å
291H98.4Very high96.2Very high8 Ų847.4 Ų47.44%0.03726%0.259CS..EExtended strand (participates in β ladder)trans-101.4142.8177.9-60.9-80.8000110.1F230 V252 F253 E255 I289 Y300F230-H291 HydrophobicContact CD1-CB 3.48Å; F230-H291 VanDerWaalsContact CD1-CB 3.48Å; F230-H291 HydrophobicContact CE1-CB 3.72Å; F230-H291 HydrophobicContact CG-CB 4.24Å; V252-H291 WeakPolarHBondContact CA-O 3.48Å; F253-H291 HydrophobicContact CB-CB 4.22Å; F253-H291 HydrophobicContact CD1-CB 4.1Å; F253-H291 AromaticContact CD1-CD2 3.39Å; F253-H291 WeakPolarHBondContact CD1-CD2 3.04Å; F253-H291 AromaticContact CD1-CG 3.98Å; F253-H291 AromaticContact CE1-CD2 3.66Å; F253-H291 PolarHBondContact N-O 3.18Å; F253-H291 PolarHBondContact O-N 2.64Å; E255-H291 IonicContact OE2-CE1 3.24Å; E255-H291 IonicContact OE2-NE2 3.87Å; E255-H291 PolarHBondContact OE2-NE2 2.91Å; I289-H291 WeakPolarHBondContact CG2-NE2 3.39Å; H291-Y300 HydrophobicContact CB-CE2 4.08Å; H291-Y300 AromaticContact ND1-CE2 3.71Å; H291-Y300 AromaticContact ND1-CZ 3.9Å; H291-Y300 PolarHBondContact ND1-OH 2.81Å
292V98.3Very high96.2Very high1 Ų151 Ų511%0.00628%0.279CS..EExtended strand (participates in β ladder)trans-128140.7176.1-175.60000109.4Y250 F251 Y300 I301 F305 I325 I371Y250-V292 HydrophobicContact CD1-CG1 3.86Å; Y250-V292 HydrophobicContact CG-CG1 4.43Å; F251-V292 WeakPolarHBondContact O-CA 3.33Å; V292-Y300 WeakPolarHBondContact O-CD2 3.5Å; V292-I301 HydrophobicContact CB-CB 4.42Å; V292-I301 HydrophobicContact CB-CD1 4.32Å; V292-I301 HydrophobicContact CG1-CD1 3.75Å; V292-I301 HydrophobicContact CG1-CG1 4.48Å; V292-I301 WeakPolarHBondContact O-CB 3.31Å; V292-I301 PolarHBondContact O-N 3.36Å; V292-F305 HydrophobicContact CG2-CD2 4.47Å; V292-F305 HydrophobicContact CG2-CE2 4.31Å; V292-I325 HydrophobicContact CG1-CD1 3.43Å; V292-I325 VanDerWaalsContact CG1-CD1 3.43Å; V292-I325 HydrophobicContact CG2-CD1 4.31Å; V292-I371 HydrophobicContact CG2-CD1 3.65Å; V292-I371 HydrophobicContact CG2-CG2 4.11Å
293A98.4Very high96Very high0 Ų051.3 Ų51.30%028%0.278CS..EExtended strand (participates in β ladder)trans-137.2144.9170.400000110.7V228 F230 Y250 F251 E299V228-A293 HydrophobicContact CB-CB 4.33Å; V228-A293 HydrophobicContact CG1-CB 3.8Å; V228-A293 HydrophobicContact CG2-CB 3.8Å; F230-A293 HydrophobicContact CE1-CB 3.57Å; F230-A293 HydrophobicContact CZ-CB 3.6Å; Y250-A293 CarbonylContact C-O 3.59Å; Y250-A293 VanDerWaalsContact CA-O 3.25Å; Y250-A293 WeakPolarHBondContact CA-O 3.47Å; F251-A293 PolarHBondContact N-O 3.3Å; F251-A293 PolarHBondContact O-N 3.5Å; A293-E299 CarbonylContact C-O 3.59Å; A293-E299 WeakPolarHBondContact CA-O 3.4Å; A293-E299 WeakPolarHBondContact CB-O 3.3Å
294K97.6Very high95.9Very high74 Ų7455.8 Ų55.832%0.32230%0.295SS..EExtended strand (participates in β ladder)trans-69.7136165.7-66.7177.4-175.5167.20109.2N249 Y250 G298 E299 I301N249-K294 CarbonylContact O-C 3.47Å; N249-K294 WeakPolarHBondContact O-CA 3.14Å; Y250-K294 HydrophobicContact CD1-CG 4.1Å; Y250-K294 HydrophobicContact CE1-CG 3.65Å; K294-G298 CarbonylContact O-C 3.58Å; K294-G298 WeakPolarHBondContact O-CA 3.48Å; K294-G298 PolarHBondContact O-N 3.18Å; K294-E299 HydrophobicContact CB-CB 4.35Å; K294-E299 PolarHBondContact N-O 2.87Å; K294-E299 IonicContact NZ-OE2 3.95Å; K294-E299 PolarHBondContact O-N 3.34Å; K294-I301 HydrophobicContact CG-CD1 4.34Å
295K95.9Very high96.1Very high26 Ų2649 Ų4911%0.11326%0.264CS..THydrogen-bonded Turntrans-72-38.4179178175.4168.5-160.30112.7E185 Y191 E248 N249 F251 G298E185-K295 VanDerWaalsContact CD-NZ 3.34Å; E185-K295 IonicContact OE1-NZ 2.81Å; E185-K295 PolarHBondContact OE1-NZ 2.84Å; E185-K295 IonicContact OE2-NZ 3.48Å; Y191-K295 WeakPolarHBondContact OH-CE 3.27Å; E248-K295 WeakPolarHBondContact O-CD 3.5Å; E248-K295 PolarHBondContact O-NZ 2.72Å; N249-K295 WeakPolarHBondContact O-CB 3.19Å; N249-K295 PolarHBondContact O-N 3.15Å; F251-K295 HydrophobicContact CD2-CB 4.33Å; F251-K295 HydrophobicContact CE1-CD 4.48Å; F251-K295 HydrophobicContact CE1-CG 4.43Å; F251-K295 HydrophobicContact CE2-CB 3.83Å; F251-K295 HydrophobicContact CE2-CG 3.81Å; F251-K295 HydrophobicContact CZ-CB 4.07Å; F251-K295 HydrophobicContact CZ-CD 4.09Å; F251-K295 HydrophobicContact CZ-CG 3.63Å; K295-G298 PolarHBondContact O-N 3.41Å
296D93.6Very high96.3Very high144 Ų14447.1 Ų47.177%0.7724%0.242SC*.THydrogen-bonded Turntrans-134.2119.8174.3-168.924.5000107.7
297P91.8Very high96.4Very high102 Ų10246.3 Ų46.366%0.66224%0.238SC*.THydrogen-bonded Turncis-81.39.812.634.6-37.6000116.7
298G95.4Very high96.5Very high19 Ų1947.3 Ų47.320%0.19625%0.245CC..THydrogen-bonded Turntrans85.266.6-173.600000111.6K294 K295K294-G298 CarbonylContact O-C 3.58Å; K294-G298 WeakPolarHBondContact O-CA 3.48Å; K294-G298 PolarHBondContact O-N 3.18Å; K295-G298 PolarHBondContact O-N 3.41Å
299E96.8Very high96.5Very high99 Ų9949.3 Ų49.346%0.46326%0.258SS..EExtended strand (participates in β ladder)trans-127.8123.9-170.1-174.9-175.7-165.900111.1A293 K294A293-E299 CarbonylContact C-O 3.59Å; A293-E299 WeakPolarHBondContact CA-O 3.4Å; A293-E299 WeakPolarHBondContact CB-O 3.3Å; K294-E299 HydrophobicContact CB-CB 4.35Å; K294-E299 PolarHBondContact N-O 2.87Å; K294-E299 IonicContact NZ-OE2 3.95Å; K294-E299 PolarHBondContact O-N 3.34Å
300Y96.9Very high96.5Very high57 Ų5748.4 Ų48.422%0.22425%0.254CS..EExtended strand (participates in β ladder)trans-70.8130.6173.6173.9-114.7000110.8F230 P231 H291 V292 D302F230-Y300 AromaticContact CD1-CD2 3.61Å; F230-Y300 HydrophobicContact CD1-CD2 3.61Å; F230-Y300 AromaticContact CD1-CE2 3.88Å; F230-Y300 HydrophobicContact CD1-CE2 3.88Å; F230-Y300 AromaticContact CE1-CD2 3.95Å; F230-Y300 HydrophobicContact CE1-CD2 3.95Å; F230-Y300 HydrophobicContact CE1-CE2 4.37Å; P231-Y300 HydrophobicContact CG-CE1 4.03Å; P231-Y300 HydrophobicContact CG-CE2 4.38Å; H291-Y300 HydrophobicContact CB-CE2 4.08Å; H291-Y300 AromaticContact ND1-CE2 3.71Å; H291-Y300 AromaticContact ND1-CZ 3.9Å; H291-Y300 PolarHBondContact ND1-OH 2.81Å; V292-Y300 WeakPolarHBondContact O-CD2 3.5Å; Y300-D302 HydrophobicContact CD1-CB 4.18Å; Y300-D302 HydrophobicContact CE1-CB 3.85Å
301I96Very high96.4Very high36 Ų3648.8 Ų48.819%0.18526%0.257CS..EExtended strand (participates in β ladder)trans-90.1106.9175.3-57-177.8000107.9Y250 V292 K294 L303Y250-I301 HydrophobicContact CD1-CD1 4.09Å; Y250-I301 HydrophobicContact CE1-CD1 3.81Å; V292-I301 HydrophobicContact CB-CB 4.42Å; V292-I301 HydrophobicContact CB-CD1 4.32Å; V292-I301 HydrophobicContact CG1-CD1 3.75Å; V292-I301 HydrophobicContact CG1-CG1 4.48Å; V292-I301 WeakPolarHBondContact O-CB 3.31Å; V292-I301 PolarHBondContact O-N 3.36Å; K294-I301 HydrophobicContact CG-CD1 4.34Å; I301-L303 HydrophobicContact CG2-CB 4.31Å; I301-L303 HydrophobicContact CG2-CD1 3.98Å; I301-L303 HydrophobicContact CG2-CG 3.97Å; I301-L303 PolarHBondContact O-N 2.81Å
302D93.8Very high96.2Very high126 Ų12648.9 Ų48.967%0.67426%0.258SS*.EExtended strand (participates in β ladder)trans-79.662.1-177.1-16624.9000112.5Y300Y300-D302 HydrophobicContact CD1-CB 4.18Å; Y300-D302 HydrophobicContact CE1-CB 3.85Å
303L92.8Very high96.1Very high51 Ų5149.6 Ų49.627%0.26726%0.261SS..EExtended strand (participates in β ladder)trans-115.9139.3170.3-68.6178.2000109.6I301 F305 V375I301-L303 HydrophobicContact CG2-CB 4.31Å; I301-L303 HydrophobicContact CG2-CD1 3.98Å; I301-L303 HydrophobicContact CG2-CG 3.97Å; I301-L303 PolarHBondContact O-N 2.81Å; L303-F305 HydrophobicContact CB-CD2 4.2Å; L303-F305 HydrophobicContact CB-CE2 3.52Å; L303-F305 HydrophobicContact CB-CZ 3.81Å; L303-F305 HydrophobicContact CD1-CE2 4.26Å; L303-F305 HydrophobicContact CD1-CZ 3.87Å; L303-F305 PolarHBondContact O-N 2.81Å; L303-V375 HydrophobicContact CD1-CB 4.34Å; L303-V375 HydrophobicContact CD1-CG2 4.09Å
304K93.7Very high96.2Very high130 Ų13050.1 Ų50.157%0.56526%0.263SS*.EExtended strand (participates in β ladder)trans-94.484.1-173.5-65.3-179.6-174.8174.50111I402K304-I402 PolarHBondContact O-N 2.97Å
305F97.9Very high96.2Very high2 Ų247.5 Ų47.51%0.00925%0.252CS..EExtended strand (participates in β ladder)trans-84.1127.3171.6-55.6-79.3000110.5I289 F290 V292 L303 I371 P372 I402 L404I289-F305 WeakPolarHBondContact CA-O 3.39Å; F290-F305 HydrophobicContact CB-CB 3.85Å; F290-F305 HydrophobicContact CD2-CB 4.33Å; F290-F305 PolarHBondContact N-O 2.76Å; F290-F305 WeakPolarHBondContact O-CB 3.36Å; V292-F305 HydrophobicContact CG2-CD2 4.47Å; V292-F305 HydrophobicContact CG2-CE2 4.31Å; L303-F305 HydrophobicContact CB-CD2 4.2Å; L303-F305 HydrophobicContact CB-CE2 3.52Å; L303-F305 HydrophobicContact CB-CZ 3.81Å; L303-F305 HydrophobicContact CD1-CE2 4.26Å; L303-F305 HydrophobicContact CD1-CZ 3.87Å; L303-F305 PolarHBondContact O-N 2.81Å; F305-I371 HydrophobicContact CD1-CG1 4.3Å; F305-I371 HydrophobicContact CD1-CG2 4.23Å; F305-I371 HydrophobicContact CD2-CG2 4.37Å; F305-I371 HydrophobicContact CE1-CG2 3.66Å; F305-I371 HydrophobicContact CE2-CG2 3.81Å; F305-I371 HydrophobicContact CG-CD1 4.49Å; F305-I371 HydrophobicContact CG-CG1 4.41Å; F305-I371 HydrophobicContact CZ-CG2 3.44Å; F305-I371 VanDerWaalsContact CZ-CG2 3.44Å; F305-P372 HydrophobicContact CE1-CG 4.27Å; F305-I402 CarbonylContact C-O 3.52Å; F305-I402 WeakPolarHBondContact CA-O 3.29Å; F305-I402 HydrophobicContact CD1-CB 3.69Å; F305-I402 HydrophobicContact CD1-CD1 3.88Å; F305-I402 HydrophobicContact CD1-CG1 4.4Å; F305-I402 HydrophobicContact CD1-CG2 3.75Å; F305-I402 HydrophobicContact CE1-CB 4.02Å; F305-I402 HydrophobicContact CE1-CD1 3.35Å; F305-I402 HydrophobicContact CE1-CG1 4.29Å; F305-I402 HydrophobicContact CE1-CG2 3.96Å; F305-I402 HydrophobicContact CZ-CD1 3.93Å; F305-L404 HydrophobicContact CB-CD1 4.17Å; F305-L404 HydrophobicContact CB-CG 4.41Å; F305-L404 HydrophobicContact CD1-CD2 4.19Å
306K98.2Very high96.4Very high67 Ų6746.9 Ų46.929%0.29125%0.25SC..EExtended strand (participates in β ladder)trans-135159.1178.7-70.8-154.1-179.9-173.90112T288 I289 M401 I402 W403 L404T288-K306 CarbonylContact O-C 3.54Å; T288-K306 VanDerWaalsContact O-CA 3.26Å; T288-K306 WeakPolarHBondContact O-CA 3.27Å; I289-K306 HydrophobicContact CG1-CD 4.33Å; I289-K306 HydrophobicContact CG1-CG 4.19Å; K306-M401 HydrophobicContact CB-CG 4.11Å; K306-M401 HydrophobicContact CB-SD 3.79Å; K306-M401 HydrophobicContact CD-CG 4.39Å; K306-M401 HydrophobicContact CD-SD 3.68Å; K306-M401 HydrophobicContact CG-CG 4.08Å; K306-M401 HydrophobicContact CG-SD 3.91Å; K306-I402 PolarHBondContact N-O 3.11Å; K306-W403 HydrophobicContact CB-CE3 4.11Å; K306-W403 HydrophobicContact CB-CZ3 4.25Å; K306-W403 CarbonylContact O-C 3.3Å; K306-W403 WeakPolarHBondContact O-CA 3.25Å; K306-L404 PolarHBondContact O-N 3.34Å
307G97.9Very high96.6Very high0 Ų040.2 Ų40.20%021%0.214CC..EExtended strand (participates in β ladder)trans-157.3-177.8171.900000112.6T288 W403T288-G307 PolarHBondContact N-O 3.08Å; T288-G307 PolarHBondContact O-N 2.82Å; G307-W403 VanDerWaalsContact C-CH2 3.42Å
308A98.1Very high96.9Very high33 Ų3335.5 Ų35.527%0.27318%0.184SC..SBendtrans-57147.2176.600000111.8T288 I310 W403T288-A308 PolarHBondContact OG1-O 2.95Å; A308-I310 PolarHBondContact O-N 3.15Å; A308-W403 HydrophobicContact CB-CZ2 4.44Å
309P98.1Very high97.1Very high42 Ų4234.6 Ų34.627%0.27317%0.174SC..  trans-62.4128.2-176.825.5-34.2000111.9P257 G334 F335P257-P309 HydrophobicContact CG-CB 4.14Å; P309-G334 CarbonylContact C-O 3.56Å; P309-G334 PolarHBondContact O-N 2.95Å; P309-G334 VanDerWaalsContact O-N 3.08Å; P309-F335 HydrophobicContact CB-CB 4.25Å
310I97.8Very high97.2Very high0 Ų032.7 Ų32.70%017%0.166CC..EExtended strand (participates in β ladder)trans-134.2143.2170.855.3169.6000111.3P257 T288 A308 L329 W332 G334 Y369P257-I310 VanDerWaalsContact CD-O 3.31Å; P257-I310 WeakPolarHBondContact CD-O 3.39Å; T288-I310 HydrophobicContact CG2-CD1 4.4Å; T288-I310 HydrophobicContact CG2-CG1 3.96Å; T288-I310 VanDerWaalsContact OG1-CG1 3.31Å; T288-I310 WeakPolarHBondContact OG1-CG1 3.46Å; T288-I310 PolarHBondContact OG1-N 2.94Å; A308-I310 PolarHBondContact O-N 3.15Å; I310-L329 HydrophobicContact CD1-CD1 4.16Å; I310-W332 CarbonylContact C-O 3.57Å; I310-W332 WeakPolarHBondContact CA-O 3.29Å; I310-G334 CarbonylContact C-O 3.58Å; I310-G334 VanDerWaalsContact CA-O 3.29Å; I310-G334 WeakPolarHBondContact CA-O 3.35Å; I310-G334 PolarHBondContact N-O 3.32Å; I310-Y369 HydrophobicContact CD1-CE2 4.23Å
311G96.8Very high97.2Very high7 Ų731.3 Ų31.37%0.07216%0.162CC..EExtended strand (participates in β ladder)trans-80.2150.5153.500000110.3S331 W332 G334G311-S331 CarbonylContact O-C 3.44Å; G311-S331 WeakPolarHBondContact O-CA 3.46Å; G311-W332 PolarHBondContact N-O 3.21Å; G311-W332 PolarHBondContact O-N 3.32Å; G311-G334 PolarHBondContact N-O 3.01Å
312M95.3Very high97.2Very high11 Ų1136.3 Ų36.35%0.05419%0.185CC..EExtended strand (participates in β ladder)trans-152.9141.3176.4177-92.1-75.700109.8V254 T256 H315 L329 C330V254-M312 HydrophobicContact CB-CE 3.47Å; V254-M312 VanDerWaalsContact CB-CE 3.47Å; V254-M312 HydrophobicContact CG1-CE 4.03Å; V254-M312 HydrophobicContact CG2-CE 3.74Å; T256-M312 HydrophobicContact CG2-CB 4.37Å; M312-H315 WeakPolarHBondContact CE-CE1 3.39Å; M312-L329 HydrophobicContact CE-CD2 4.18Å; M312-L329 HydrophobicContact CG-CB 4.45Å; M312-L329 HydrophobicContact CG-CD1 4.49Å; M312-L329 HydrophobicContact CG-CD2 4.35Å; M312-C330 WeakPolarHBondContact CG-O 3.29Å
313F96.4Very high97.3Very high15 Ų1532 Ų327%0.06617%0.169CC..EExtended strand (participates in β ladder)trans-111.2-55.8170.5-58.4-60.4000110.1Y240 H242 S243 W332 F337 V338 Y339Y240-F313 AromaticContact CE1-CD1 3.97Å; Y240-F313 HydrophobicContact CE1-CD1 3.97Å; Y240-F313 AromaticContact CE1-CE1 3.85Å; Y240-F313 HydrophobicContact CE1-CE1 3.85Å; H242-F313 HydrophobicContact CB-CB 4.42Å; H242-F313 HydrophobicContact CB-CD1 4.28Å; H242-F313 WeakPolarHBondContact CB-O 3.26Å; H242-F313 PolarHBondContact CD2-O 3.01Å; S243-F313 WeakPolarHBondContact CB-O 3.23Å; S243-F313 PolarHBondContact OG-O 2.83Å; F313-W332 AromaticContact CD2-CD1 3.98Å; F313-W332 AromaticContact CD2-NE1 3.62Å; F313-W332 AromaticContact CE2-CD1 3.95Å; F313-W332 AromaticContact CE2-NE1 3.72Å; F313-F337 HydrophobicContact CE1-CE2 4.24Å; F313-V338 HydrophobicContact CE2-CB 3.88Å; F313-V338 HydrophobicContact CE2-CG1 3.93Å; F313-V338 HydrophobicContact CE2-CG2 4.39Å; F313-V338 HydrophobicContact CZ-CB 3.78Å; F313-V338 HydrophobicContact CZ-CG1 4.22Å; F313-Y339 AromaticContact CD1-CE1 3.82Å; F313-Y339 HydrophobicContact CD1-CE1 3.82Å; F313-Y339 AromaticContact CD1-CZ 3.94Å; F313-Y339 AromaticContact CE1-CD1 3.7Å; F313-Y339 HydrophobicContact CE1-CD1 3.7Å; F313-Y339 AromaticContact CE1-CE1 3.06Å; F313-Y339 HydrophobicContact CE1-CE1 3.06Å; F313-Y339 HydrophobicContact CE1-CE2 4.34Å; F313-Y339 AromaticContact CE1-CZ 3.43Å; F313-Y339 VanDerWaalsContact CE1-CZ 3.43Å; F313-Y339 HydrophobicContact CE2-CD1 4.36Å; F313-Y339 AromaticContact CE2-CE1 3.96Å; F313-Y339 HydrophobicContact CE2-CE1 3.96Å; F313-Y339 AromaticContact CZ-CD1 3.42Å; F313-Y339 HydrophobicContact CZ-CD1 3.42Å; F313-Y339 VanDerWaalsContact CZ-CD1 3.42Å; F313-Y339 AromaticContact CZ-CE1 3.13Å; F313-Y339 HydrophobicContact CZ-CE1 3.13Å; F313-Y339 HydrophobicContact CZ-CG 4.49Å
314H98.8Very high97.6Very high11 Ų1130.2 Ų30.25%0.05116%0.16CC..EExtended strand (participates in β ladder)trans-113.9126.7-169.9-53.6109.6000113.2H181 H242 S243 C330 E418 P420 H527H181-H314 AromaticContact CE1-CD2 3.6Å; H181-H314 AromaticContact CE1-NE2 3.63Å; H181-H314 AromaticContact NE2-CD2 3.79Å; H181-H314 AromaticContact NE2-NE2 3.61Å; H242-H314 AromaticContact CD2-CD2 3.73Å; H242-H314 AromaticContact CD2-NE2 3.69Å; H242-H314 AromaticContact NE2-CD2 3.66Å; H242-H314 AromaticContact NE2-CE1 3.95Å; H242-H314 AromaticContact NE2-NE2 3.15Å; H242-H314 PolarHBondContact NE2-NE2 3.01Å; H242-H314 VanDerWaalsContact NE2-NE2 3.15Å; S243-H314 WeakPolarHBondContact OG-CA 3.12Å; H314-C330 HydrophobicContact CB-CB 4.44Å; H314-C330 PolarHBondContact O-N 3.48Å; H314-E418 IonicContact CE1-OE2 3.23Å; H314-E418 IonicContact CG-OE2 2.71Å; H314-E418 IonicContact ND1-OE2 3.5Å; H314-E418 PolarHBondContact ND1-OE2 3.18Å; H314-P420 HydrophobicContact CB-CG 3.5Å; H314-H527 AromaticContact CE1-CE1 3.91Å; H314-H527 AromaticContact NE2-CE1 3.25Å; H314-H527 PolarHBondContact NE2-CE1 3.19Å; H314-H527 VanDerWaalsContact NE2-CE1 3.25Å; H314-H527 AromaticContact NE2-NE2 3.35Å; H314-H527 PolarHBondContact NE2-NE2 3.49Å
315H98.8Very high97.8Very high20 Ų2024 Ų249%0.09313%0.133CC..EExtended strand (participates in β ladder)trans-69.7142.9154.4-6870.3000109.3S243 F244 G245 M312 L329S243-H315 PolarHBondContact O-CE1 2.86Å; S243-H315 PolarHBondContact OG-N 2.98Å; S243-H315 PolarHBondContact OG-ND1 2.84Å; F244-H315 VanDerWaalsContact C-CE1 3.46Å; F244-H315 WeakPolarHBondContact CA-CE1 3.48Å; G245-H315 PolarHBondContact N-CD2 3.38Å; G245-H315 PolarHBondContact N-NE2 2.76Å; M312-H315 WeakPolarHBondContact CE-CE1 3.39Å; H315-L329 HydrophobicContact CB-CD2 4.18Å; H315-L329 WeakPolarHBondContact CD2-CD2 3.25Å
316I98.9Very high97.9Very high12 Ų1224 Ų246%0.06213%0.132CC..EExtended strand (participates in β ladder)trans-89.1-57.6172.6-55.9-177.9000109.1D328 V366 F417 P420 I422 Y432 A435I316-D328 HydrophobicContact CB-CB 3.98Å; I316-D328 WeakPolarHBondContact CB-O 3.48Å; I316-D328 HydrophobicContact CD1-CB 4.31Å; I316-D328 HydrophobicContact CG1-CB 4.46Å; I316-D328 PolarHBondContact N-O 2.75Å; I316-V366 HydrophobicContact CD1-CG1 3.4Å; I316-V366 HydrophobicContact CD1-CG2 4.44Å; I316-F417 HydrophobicContact CD1-CD1 4.45Å; I316-F417 HydrophobicContact CD1-CE1 4.13Å; I316-P420 HydrophobicContact CB-CB 4.22Å; I316-P420 HydrophobicContact CD1-CB 4.46Å; I316-P420 HydrophobicContact CG1-CB 3.71Å; I316-P420 HydrophobicContact CG1-CG 3.95Å; I316-P420 HydrophobicContact CG2-CB 4.21Å; I316-I422 HydrophobicContact CG2-CG2 4.09Å; I316-Y432 HydrophobicContact CG2-CE2 4.24Å; I316-Y432 VanDerWaalsContact CG2-OH 3.31Å; I316-Y432 WeakPolarHBondContact CG2-OH 3.46Å; I316-A435 HydrophobicContact CG2-CB 3.64Å
317N98.9Very high97.9Very high5 Ų520.8 Ų20.83%0.02712%0.118CC..EExtended strand (participates in β ladder)trans-159.9165.6175.4-161.112.5000110.5F327 D328 I422 Y427 G429 K430 Y432N317-F327 WeakPolarHBondContact O-CA 3.12Å; N317-D328 PolarHBondContact O-N 3.36Å; N317-I422 HydrophobicContact CB-CD1 4.11Å; N317-Y427 PolarHBondContact ND2-O 2.78Å; N317-G429 PolarHBondContact OD1-N 3.33Å; N317-K430 PolarHBondContact ND2-O 2.78Å; N317-Y432 HydrophobicContact CB-CD1 3.98Å; N317-Y432 HydrophobicContact CB-CE1 3.55Å; N317-Y432 HydrophobicContact CB-CE2 4.19Å; N317-Y432 HydrophobicContact CB-CG 4.5Å; N317-Y432 WeakPolarHBondContact ND2-CD1 3.47Å
318T98.8Very high98Very high2 Ų220.8 Ų20.81%0.01212%0.118CC..EExtended strand (participates in β ladder)trans-143.8133.3176.2-61.10000109G245 V252 I325 V326 F327 G429G245-T318 WeakPolarHBondContact CA-OG1 3.4Å; V252-T318 HydrophobicContact CG2-CG2 3.89Å; T318-I325 HydrophobicContact CG2-CG2 3.7Å; T318-V326 CarbonylContact C-O 3.4Å; T318-V326 WeakPolarHBondContact CA-O 3.27Å; T318-F327 HydrophobicContact CG2-CB 3.99Å; T318-F327 VanDerWaalsContact OG1-CB 3.31Å; T318-F327 WeakPolarHBondContact OG1-CB 3.33Å; T318-G429 CarbonylContact O-C 3.59Å; T318-G429 WeakPolarHBondContact O-CA 3.47Å
319Y98.8Very high98Very high0 Ų019.2 Ų19.20%011%0.105CC..EExtended strand (participates in β ladder)trans-150.6168.1-178.667-89.5000112.1D321 I325 V326 Y389 N431 Y432Y319-D321 HydrophobicContact CD2-CB 4.39Å; Y319-D321 HydrophobicContact CE2-CB 4.08Å; Y319-I325 CarbonylContact O-C 3.54Å; Y319-I325 WeakPolarHBondContact O-CA 3.3Å; Y319-V326 HydrophobicContact CD1-CB 4.21Å; Y319-V326 HydrophobicContact CD2-CB 4.28Å; Y319-V326 HydrophobicContact CE1-CB 3.74Å; Y319-V326 HydrophobicContact CE1-CG1 3.72Å; Y319-V326 HydrophobicContact CE2-CB 3.82Å; Y319-V326 HydrophobicContact CE2-CG1 4.39Å; Y319-V326 HydrophobicContact CE2-CG2 3.9Å; Y319-V326 HydrophobicContact CG-CB 4.46Å; Y319-V326 PolarHBondContact N-O 3.4Å; Y319-V326 PolarHBondContact O-N 3.31Å; Y319-V326 WeakPolarHBondContact OH-CG1 3.44Å; Y319-Y389 PolarHBondContact OH-OH 2.98Å; Y319-N431 HydrophobicContact CD2-CB 3.77Å; Y319-N431 HydrophobicContact CE2-CB 3.93Å; Y319-N431 HydrophobicContact CG-CB 4.28Å; Y319-Y432 HydrophobicContact CD1-CD1 4.17Å; Y319-Y432 HydrophobicContact CD1-CE1 4.37Å; Y319-Y432 HydrophobicContact CE1-CD1 4.11Å; Y319-Y432 HydrophobicContact CE1-CE1 4.14Å
320E98.5Very high98Very high60 Ų6017.2 Ų17.228%0.289%0.093SC..EExtended strand (participates in β ladder)trans-104.7138.1178.7-64.5164.9-122.600110.3S247 E248 N249 Y250 F324S247-E320 PolarHBondContact OG-OE1 3.44Å; E248-E320 PolarHBondContact N-OE1 3.25Å; N249-E320 VanDerWaalsContact CB-OE1 3.29Å; N249-E320 WeakPolarHBondContact CB-OE1 3.35Å; N249-E320 PolarHBondContact N-OE1 3.08Å; N249-E320 PolarHBondContact ND2-OE1 2.98Å; N249-E320 VanDerWaalsContact ND2-OE1 3.12Å; N249-E320 PolarHBondContact ND2-OE2 3.27Å; Y250-E320 HydrophobicContact CD2-CG 3.95Å; Y250-E320 HydrophobicContact CE2-CG 4.3Å; Y250-E320 WeakPolarHBondContact CE2-OE2 3.31Å; E320-F324 WeakPolarHBondContact CA-O 3.35Å
321D97.8Very high98Very high28 Ų2817.3 Ų17.315%0.159%0.093CC..EExtended strand (participates in β ladder)trans-148.7124171.8-167.3-5000110.3Y319 G323 F324 L387 Y389Y319-D321 HydrophobicContact CD2-CB 4.39Å; Y319-D321 HydrophobicContact CE2-CB 4.08Å; D321-G323 VanDerWaalsContact C-N 3.3Å; D321-G323 PolarHBondContact O-N 3.12Å; D321-G323 VanDerWaalsContact O-N 3.1Å; D321-F324 PolarHBondContact N-O 2.88Å; D321-F324 WeakPolarHBondContact O-CB 3.4Å; D321-F324 WeakPolarHBondContact O-CD2 3.48Å; D321-F324 PolarHBondContact O-N 3.27Å; D321-L387 HydrophobicContact CB-CD2 4.48Å; D321-Y389 WeakPolarHBondContact OD2-CE1 3.47Å; D321-Y389 PolarHBondContact OD2-OH 3.26Å
322Q95.8Very high98.1Very high141 Ų14117.5 Ų17.566%0.6599%0.092SC*.THydrogen-bonded Turntrans46.843171.6-70.2162.769.300115.4F324 L387Q322-F324 VanDerWaalsContact O-CD2 3.23Å; Q322-F324 WeakPolarHBondContact O-CD2 3.29Å; Q322-F324 WeakPolarHBondContact O-CE2 3.29Å; Q322-L387 HydrophobicContact CB-CD2 4Å
323G96Very high98.2Very high34 Ų3420.7 Ų20.735%0.35111%0.105SC..THydrogen-bonded Turntrans8412.9179.900000114.6D321 L373D321-G323 VanDerWaalsContact C-N 3.3Å; D321-G323 PolarHBondContact O-N 3.12Å; D321-G323 VanDerWaalsContact O-N 3.1Å; G323-L373 VanDerWaalsContact O-CB 3.24Å; G323-L373 WeakPolarHBondContact O-CB 3.31Å; G323-L373 WeakPolarHBondContact O-CG 3.48Å; G323-L373 PolarHBondContact O-N 2.66Å
324F98.4Very high98.2Very high15 Ų1521.2 Ų21.27%0.06612%0.115CC..EExtended strand (participates in β ladder)trans-121.1150.9174.8-58.3-90.6000111.1E320 D321 Q322 V370 I371 P372 L384 S386 L387E320-F324 WeakPolarHBondContact CA-O 3.35Å; D321-F324 PolarHBondContact N-O 2.88Å; D321-F324 WeakPolarHBondContact O-CB 3.4Å; D321-F324 WeakPolarHBondContact O-CD2 3.48Å; D321-F324 PolarHBondContact O-N 3.27Å; Q322-F324 VanDerWaalsContact O-CD2 3.23Å; Q322-F324 WeakPolarHBondContact O-CD2 3.29Å; Q322-F324 WeakPolarHBondContact O-CE2 3.29Å; F324-V370 HydrophobicContact CB-CG1 3.78Å; F324-V370 HydrophobicContact CD1-CG1 3.72Å; F324-V370 HydrophobicContact CG-CG1 3.98Å; F324-I371 CarbonylContact C-O 3.53Å; F324-I371 VanDerWaalsContact CA-O 3.25Å; F324-I371 WeakPolarHBondContact CA-O 3.35Å; F324-P372 HydrophobicContact CD1-CB 4.01Å; F324-P372 HydrophobicContact CE1-CB 3.82Å; F324-L384 VanDerWaalsContact CE1-O 3.29Å; F324-L384 WeakPolarHBondContact CE1-O 3.16Å; F324-L384 WeakPolarHBondContact CZ-O 3.23Å; F324-S386 WeakPolarHBondContact CE2-OG 3.22Å; F324-S386 VanDerWaalsContact CZ-OG 3.31Å; F324-S386 WeakPolarHBondContact CZ-OG 3.09Å; F324-L387 HydrophobicContact CB-CD1 4Å; F324-L387 HydrophobicContact CD2-CD1 4.03Å; F324-L387 HydrophobicContact CD2-CD2 3.87Å; F324-L387 HydrophobicContact CD2-CG 3.71Å; F324-L387 HydrophobicContact CE2-CD2 4.32Å; F324-L387 HydrophobicContact CE2-CG 4.12Å; F324-L387 HydrophobicContact CG-CD1 4.05Å; F324-L387 HydrophobicContact CG-CG 4.17Å
325I98.7Very high98Very high0 Ų024.1 Ų24.10%013%0.127CC..EExtended strand (participates in β ladder)trans-98.5123.4162.4-57.9166.3000108Y250 V252 V292 T318 Y319 F327 V370 I371 L373Y250-I325 HydrophobicContact CD1-CD1 3.99Å; Y250-I325 HydrophobicContact CD2-CD1 4.03Å; Y250-I325 HydrophobicContact CD2-CG1 4.15Å; Y250-I325 HydrophobicContact CG-CD1 3.62Å; Y250-I325 HydrophobicContact CG-CG1 4.25Å; V252-I325 HydrophobicContact CG2-CD1 4.39Å; V252-I325 HydrophobicContact CG2-CG2 3.71Å; V292-I325 HydrophobicContact CG1-CD1 3.43Å; V292-I325 VanDerWaalsContact CG1-CD1 3.43Å; V292-I325 HydrophobicContact CG2-CD1 4.31Å; T318-I325 HydrophobicContact CG2-CG2 3.7Å; Y319-I325 CarbonylContact O-C 3.54Å; Y319-I325 WeakPolarHBondContact O-CA 3.3Å; I325-F327 HydrophobicContact CG2-CD1 4.46Å; I325-V370 CarbonylContact O-C 3.52Å; I325-V370 WeakPolarHBondContact O-CA 3.34Å; I325-I371 HydrophobicContact CB-CB 4.4Å; I325-I371 PolarHBondContact N-O 2.84Å; I325-I371 PolarHBondContact O-N 3.17Å; I325-L373 HydrophobicContact CD1-CD2 3.63Å; I325-L373 HydrophobicContact CD1-CG 4.5Å; I325-L373 HydrophobicContact CG1-CD1 4.3Å; I325-L373 HydrophobicContact CG1-CD2 3.86Å; I325-L373 HydrophobicContact CG1-CG 4.2Å
326V98.9Very high97.9Very high0 Ų026.3 Ų26.30%014%0.138CC..EExtended strand (participates in β ladder)trans-106.8130.1174.3-173.60000108.6T318 Y319 R368 V370 L387T318-V326 CarbonylContact C-O 3.4Å; T318-V326 WeakPolarHBondContact CA-O 3.27Å; Y319-V326 HydrophobicContact CD1-CB 4.21Å; Y319-V326 HydrophobicContact CD2-CB 4.28Å; Y319-V326 HydrophobicContact CE1-CB 3.74Å; Y319-V326 HydrophobicContact CE1-CG1 3.72Å; Y319-V326 HydrophobicContact CE2-CB 3.82Å; Y319-V326 HydrophobicContact CE2-CG1 4.39Å; Y319-V326 HydrophobicContact CE2-CG2 3.9Å; Y319-V326 HydrophobicContact CG-CB 4.46Å; Y319-V326 PolarHBondContact N-O 3.4Å; Y319-V326 PolarHBondContact O-N 3.31Å; Y319-V326 WeakPolarHBondContact OH-CG1 3.44Å; V326-R368 HydrophobicContact CG1-CG 3.8Å; V326-V370 HydrophobicContact CG1-CG2 4.29Å; V326-V370 HydrophobicContact CG2-CG1 4.41Å; V326-V370 HydrophobicContact CG2-CG2 4.22Å; V326-L387 HydrophobicContact CG2-CD1 3.92Å
327F98.8Very high97.8Very high0 Ų026.1 Ų26.10%014%0.136CC..EExtended strand (participates in β ladder)trans-141.1143176.560.6-78.9000111.7V252 V254 F290 N317 T318 I325 L329 R368 Y369 I371V252-F327 HydrophobicContact CG1-CD1 4.22Å; V252-F327 HydrophobicContact CG1-CD2 4.35Å; V252-F327 HydrophobicContact CG1-CE1 4.18Å; V252-F327 HydrophobicContact CG1-CE2 4.3Å; V252-F327 HydrophobicContact CG1-CG 4.3Å; V252-F327 HydrophobicContact CG1-CZ 4.21Å; V254-F327 HydrophobicContact CG2-CE2 4.21Å; F290-F327 AromaticContact CD1-CE2 3.88Å; F290-F327 HydrophobicContact CD1-CE2 3.88Å; F290-F327 AromaticContact CD1-CZ 3.56Å; F290-F327 HydrophobicContact CD1-CZ 3.56Å; F290-F327 AromaticContact CE1-CE2 3.99Å; F290-F327 HydrophobicContact CE1-CE2 3.99Å; F290-F327 AromaticContact CE1-CZ 3.93Å; F290-F327 HydrophobicContact CE1-CZ 3.93Å; F290-F327 HydrophobicContact CG-CZ 4.37Å; N317-F327 WeakPolarHBondContact O-CA 3.12Å; T318-F327 HydrophobicContact CG2-CB 3.99Å; T318-F327 VanDerWaalsContact OG1-CB 3.31Å; T318-F327 WeakPolarHBondContact OG1-CB 3.33Å; I325-F327 HydrophobicContact CG2-CD1 4.46Å; F327-L329 HydrophobicContact CD2-CD1 4.14Å; F327-L329 HydrophobicContact CD2-CD2 4Å; F327-L329 HydrophobicContact CD2-CG 3.92Å; F327-L329 HydrophobicContact CE2-CD1 3.91Å; F327-L329 HydrophobicContact CE2-CG 4.22Å; F327-R368 WeakPolarHBondContact O-CA 3.17Å; F327-Y369 AromaticContact CE2-CD2 3.98Å; F327-Y369 HydrophobicContact CE2-CD2 3.98Å; F327-Y369 HydrophobicContact CE2-CG 4.02Å; F327-Y369 HydrophobicContact CZ-CD2 4.36Å; F327-Y369 AromaticContact CZ-CG 3.93Å; F327-Y369 HydrophobicContact CZ-CG 3.93Å; F327-Y369 PolarHBondContact N-O 3.49Å; F327-Y369 PolarHBondContact O-N 3.15Å; F327-I371 HydrophobicContact CE1-CD1 3.54Å; F327-I371 HydrophobicContact CE1-CG1 3.87Å; F327-I371 HydrophobicContact CZ-CD1 4.07Å
328D98.9Very high97.7Very high0 Ų026 Ų260%014%0.136CC..EExtended strand (participates in β ladder)trans-115.3135.7-176-61.7-28.3000109.3I316 N317 R367 R368 L409 Y432I316-D328 HydrophobicContact CB-CB 3.98Å; I316-D328 WeakPolarHBondContact CB-O 3.48Å; I316-D328 HydrophobicContact CD1-CB 4.31Å; I316-D328 HydrophobicContact CG1-CB 4.46Å; I316-D328 PolarHBondContact N-O 2.75Å; N317-D328 PolarHBondContact O-N 3.36Å; D328-R367 CarbonylContact C-O 3.58Å; D328-R367 WeakPolarHBondContact CA-O 3.36Å; D328-R368 WeakPolarHBondContact OD1-CA 3.31Å; D328-R368 WeakPolarHBondContact OD1-CB 3.37Å; D328-R368 VanDerWaalsContact OD1-CG 3.26Å; D328-R368 WeakPolarHBondContact OD1-CG 3.36Å; D328-R368 IonicContact OD1-CZ 3.24Å; D328-R368 IonicContact OD1-NE 3.93Å; D328-R368 PolarHBondContact OD1-NE 2.8Å; D328-R368 IonicContact OD1-NH2 3.78Å; D328-R368 PolarHBondContact OD1-NH2 2.58Å; D328-R368 IonicContact OD2-CZ 3.4Å; D328-R368 IonicContact OD2-NE 3.94Å; D328-R368 IonicContact OD2-NH2 2.73Å; D328-R368 PolarHBondContact OD2-NH2 3.29Å; D328-L409 HydrophobicContact CB-CD1 4.36Å; D328-Y432 WeakPolarHBondContact CB-OH 3.44Å; D328-Y432 VanDerWaalsContact OD2-CE1 3.25Å; D328-Y432 WeakPolarHBondContact OD2-CE1 3.37Å; D328-Y432 VanDerWaalsContact OD2-CZ 3.29Å; D328-Y432 PolarHBondContact OD2-OH 2.96Å
329L98.6Very high97.6Very high0 Ų026.4 Ų26.40%014%0.138CC..EExtended strand (participates in β ladder)trans-129.8142.2-172.7-59.2179.6000112V254 I310 M312 H315 F327 V366 R367 Y369V254-L329 HydrophobicContact CG2-CD1 4.18Å; I310-L329 HydrophobicContact CD1-CD1 4.16Å; M312-L329 HydrophobicContact CE-CD2 4.18Å; M312-L329 HydrophobicContact CG-CB 4.45Å; M312-L329 HydrophobicContact CG-CD1 4.49Å; M312-L329 HydrophobicContact CG-CD2 4.35Å; H315-L329 HydrophobicContact CB-CD2 4.18Å; H315-L329 WeakPolarHBondContact CD2-CD2 3.25Å; F327-L329 HydrophobicContact CD2-CD1 4.14Å; F327-L329 HydrophobicContact CD2-CD2 4Å; F327-L329 HydrophobicContact CD2-CG 3.92Å; F327-L329 HydrophobicContact CE2-CD1 3.91Å; F327-L329 HydrophobicContact CE2-CG 4.22Å; L329-V366 VanDerWaalsContact O-CA 3.31Å; L329-V366 WeakPolarHBondContact O-CA 3.33Å; L329-R367 PolarHBondContact N-O 3.04Å; L329-R367 PolarHBondContact O-N 3.04Å; L329-Y369 HydrophobicContact CD1-CD2 4.04Å; L329-Y369 HydrophobicContact CD1-CE2 4.1Å
330C98.8Very high97.5Very high1 Ų129.6 Ų29.61%0.00715%0.154CC..EExtended strand (participates in β ladder)trans-81.5109.8156.5-62.30000108.3M312 H314 F417M312-C330 WeakPolarHBondContact CG-O 3.29Å; H314-C330 HydrophobicContact CB-CB 4.44Å; H314-C330 PolarHBondContact O-N 3.48Å; C330-F417 PolarHBondContact SG-O 2.91Å
331S98.2Very high97.4Very high1 Ų128 Ų281%0.00715%0.146CC..EExtended strand (participates in β ladder)trans-121.5158.2-172.373.70000112.7G311 P364 E365 R367G311-S331 CarbonylContact O-C 3.44Å; G311-S331 WeakPolarHBondContact O-CA 3.46Å; S331-P364 CarbonylContact O-C 3.4Å; S331-P364 VanDerWaalsContact O-CA 3.31Å; S331-P364 WeakPolarHBondContact O-CA 3.45Å; S331-E365 WeakPolarHBondContact CA-O 3.4Å; S331-E365 PolarHBondContact N-O 2.86Å; S331-E365 PolarHBondContact O-N 3.37Å; S331-E365 VanDerWaalsContact O-O 3.13Å; S331-E365 PolarHBondContact OG-O 2.76Å; S331-R367 WeakPolarHBondContact OG-CD 3.43Å; S331-R367 WeakPolarHBondContact OG-CG 3.4Å
332W98.4Very high97.4Very high11 Ų1127.6 Ų27.64%0.04214%0.144CC..EExtended strand (participates in β ladder)trans-126.3117.8178.8-64.886.2000108.8I310 G311 F313 G334 V338 P362 P364 A416 E418 F443I310-W332 CarbonylContact C-O 3.57Å; I310-W332 WeakPolarHBondContact CA-O 3.29Å; G311-W332 PolarHBondContact N-O 3.21Å; G311-W332 PolarHBondContact O-N 3.32Å; F313-W332 AromaticContact CD2-CD1 3.98Å; F313-W332 AromaticContact CD2-NE1 3.62Å; F313-W332 AromaticContact CE2-CD1 3.95Å; F313-W332 AromaticContact CE2-NE1 3.72Å; W332-G334 PolarHBondContact O-N 3.37Å; W332-V338 HydrophobicContact CB-CG2 3.64Å; W332-V338 HydrophobicContact CD2-CG1 4.18Å; W332-V338 HydrophobicContact CD2-CG2 3.8Å; W332-V338 HydrophobicContact CE3-CG1 4.27Å; W332-V338 HydrophobicContact CE3-CG2 4.09Å; W332-V338 HydrophobicContact CG-CG2 3.6Å; W332-V338 HydrophobicContact CZ2-CG1 4.47Å; W332-V338 HydrophobicContact CZ3-CG1 4.46Å; W332-P362 HydrophobicContact CB-CB 3.81Å; W332-P362 HydrophobicContact CE3-CB 4.31Å; W332-P364 HydrophobicContact CD2-CB 4.13Å; W332-P364 HydrophobicContact CE3-CB 3.84Å; W332-P364 HydrophobicContact CE3-CG 4.28Å; W332-P364 HydrophobicContact CH2-CB 3.98Å; W332-P364 HydrophobicContact CH2-CG 4.21Å; W332-P364 HydrophobicContact CZ2-CB 4.25Å; W332-P364 HydrophobicContact CZ3-CB 3.76Å; W332-P364 HydrophobicContact CZ3-CG 3.86Å; W332-A416 HydrophobicContact CH2-CB 3.83Å; W332-A416 HydrophobicContact CZ2-CB 3.92Å; W332-E418 HydrophobicContact CZ2-CG 3.94Å; W332-E418 PolarHBondContact NE1-OE1 3.41Å; W332-F443 AromaticContact CH2-CD1 3.98Å; W332-F443 HydrophobicContact CH2-CD1 3.98Å; W332-F443 AromaticContact CH2-CE1 3.53Å; W332-F443 HydrophobicContact CH2-CE1 3.53Å; W332-F443 HydrophobicContact CH2-CZ 4.48Å; W332-F443 HydrophobicContact CZ2-CE1 4.39Å; W332-F443 HydrophobicContact CZ3-CD1 4.46Å; W332-F443 AromaticContact CZ3-CE1 3.62Å; W332-F443 HydrophobicContact CZ3-CE1 3.62Å; W332-F443 HydrophobicContact CZ3-CZ 4.16Å
333K97.5Very high97.5Very high79 Ų7924.1 Ų24.134%0.34313%0.125SC..EExtended strand (participates in β ladder)trans-66.1127.2-173.3-64.3-173.6-170-168.60111.7P362 Q363 E365K333-P362 WeakPolarHBondContact O-CA 3.17Å; K333-P362 WeakPolarHBondContact O-CB 3.48Å; K333-Q363 HydrophobicContact CB-CB 4.4Å; K333-Q363 HydrophobicContact CD-CB 4.36Å; K333-Q363 HydrophobicContact CD-CG 4.42Å; K333-Q363 WeakPolarHBondContact CG-O 2.97Å; K333-Q363 PolarHBondContact N-O 2.84Å; K333-E365 WeakPolarHBondContact CE-OE1 3.39Å; K333-E365 WeakPolarHBondContact CE-OE2 3.42Å; K333-E365 VanDerWaalsContact NZ-CD 3.35Å; K333-E365 IonicContact NZ-OE1 3.02Å; K333-E365 PolarHBondContact NZ-OE1 3.38Å; K333-E365 IonicContact NZ-OE2 3.21Å; K333-E365 PolarHBondContact NZ-OE2 3.02Å
334G95.9Very high97.6Very high26 Ų2622.6 Ų22.627%0.26811%0.108SC..SBendtrans110.5-174.617800000112.4P309 I310 G311 W332P309-G334 CarbonylContact C-O 3.56Å; P309-G334 PolarHBondContact O-N 2.95Å; P309-G334 VanDerWaalsContact O-N 3.08Å; I310-G334 CarbonylContact C-O 3.58Å; I310-G334 VanDerWaalsContact CA-O 3.29Å; I310-G334 WeakPolarHBondContact CA-O 3.35Å; I310-G334 PolarHBondContact N-O 3.32Å; G311-G334 PolarHBondContact N-O 3.01Å; W332-G334 PolarHBondContact O-N 3.37Å
335F95.3Very high97.6Very high71 Ų7125.6 Ų25.631%0.31114%0.136SC..SBendtrans-107.9-10.9-177.352.4-104.1000113.6P257 S282 E284 P309P257-F335 HydrophobicContact CB-CB 3.93Å; P257-F335 HydrophobicContact CG-CB 3.59Å; S282-F335 VanDerWaalsContact CB-O 3.25Å; S282-F335 WeakPolarHBondContact CB-O 3.13Å; S282-F335 PolarHBondContact OG-O 3.46Å; E284-F335 HydrophobicContact CB-CD1 4.49Å; E284-F335 HydrophobicContact CB-CE1 4.29Å; E284-F335 HydrophobicContact CB-CZ 4.37Å; E284-F335 HydrophobicContact CG-CD1 4.5Å; E284-F335 HydrophobicContact CG-CD2 4.12Å; E284-F335 HydrophobicContact CG-CE1 4.15Å; E284-F335 HydrophobicContact CG-CE2 3.74Å; E284-F335 HydrophobicContact CG-CG 4.48Å; E284-F335 HydrophobicContact CG-CZ 3.75Å; P309-F335 HydrophobicContact CB-CB 4.25Å
336E95.5Very high97.5Very high66 Ų6628.7 Ų28.731%0.30815%0.153SC..SBendtrans-65.7137.3-179.3-169.1-173.6174.600110.5V338 Y341 P362E336-V338 PolarHBondContact O-N 2.85Å; E336-Y341 VanDerWaalsContact CD-OH 3.26Å; E336-Y341 WeakPolarHBondContact OE1-CE2 3.22Å; E336-Y341 PolarHBondContact OE1-OH 2.9Å; E336-Y341 PolarHBondContact OE2-OH 3.12Å; E336-P362 HydrophobicContact CB-CG 4.1Å
337F96.6Very high97.4Very high8 Ų828.9 Ų28.94%0.03515%0.154CC..  trans-73116.2-179.9-169.3-156.3000111.3F103 Y240 V258 M277 F280 F313 Y339 N340F103-F337 HydrophobicContact CZ-CE1 4.09Å; F103-F337 HydrophobicContact CZ-CZ 4.37Å; Y240-F337 AromaticContact CD1-CE2 3.91Å; Y240-F337 HydrophobicContact CD1-CE2 3.91Å; Y240-F337 HydrophobicContact CD1-CZ 4.23Å; Y240-F337 HydrophobicContact CE1-CE2 4.13Å; Y240-F337 HydrophobicContact CE1-CZ 4.34Å; V258-F337 HydrophobicContact CB-CD2 4.45Å; V258-F337 HydrophobicContact CG1-CB 4.12Å; V258-F337 HydrophobicContact CG1-CD1 4.21Å; V258-F337 HydrophobicContact CG1-CD2 3.67Å; V258-F337 HydrophobicContact CG1-CE2 4.03Å; V258-F337 HydrophobicContact CG1-CG 3.76Å; V258-F337 HydrophobicContact CG1-CZ 4.43Å; V258-F337 HydrophobicContact CG2-CB 4.17Å; V258-F337 HydrophobicContact CG2-CD2 4.05Å; V258-F337 HydrophobicContact CG2-CG 4.39Å; M277-F337 HydrophobicContact CE-CD1 3.69Å; M277-F337 HydrophobicContact CE-CE1 4.07Å; M277-F337 HydrophobicContact SD-CD1 3.92Å; M277-F337 HydrophobicContact SD-CE1 3.72Å; F280-F337 HydrophobicContact CB-CD1 3.85Å; F280-F337 HydrophobicContact CB-CE1 4.02Å; F280-F337 HydrophobicContact CD1-CD1 4.23Å; F280-F337 AromaticContact CD1-CE1 3.74Å; F280-F337 HydrophobicContact CD1-CE1 3.74Å; F280-F337 HydrophobicContact CD1-CZ 4.14Å; F280-F337 HydrophobicContact CD2-CD1 4.45Å; F280-F337 AromaticContact CD2-CE1 3.79Å; F280-F337 HydrophobicContact CD2-CE1 3.79Å; F280-F337 HydrophobicContact CE1-CE1 4.09Å; F280-F337 HydrophobicContact CE1-CZ 4.12Å; F280-F337 HydrophobicContact CE2-CE1 4.15Å; F280-F337 AromaticContact CG-CD1 3.92Å; F280-F337 HydrophobicContact CG-CD1 3.92Å; F280-F337 AromaticContact CG-CE1 3.56Å; F280-F337 HydrophobicContact CG-CE1 3.56Å; F280-F337 HydrophobicContact CG-CZ 4.38Å; F280-F337 HydrophobicContact CZ-CE1 4.28Å; F280-F337 HydrophobicContact CZ-CZ 4.37Å; F313-F337 HydrophobicContact CE1-CE2 4.24Å; F337-Y339 HydrophobicContact CD2-CG 4.43Å; F337-Y339 AromaticContact CE1-CD2 3.89Å; F337-Y339 HydrophobicContact CE1-CD2 3.89Å; F337-Y339 HydrophobicContact CE1-CG 4.09Å; F337-Y339 HydrophobicContact CE2-CD1 4.22Å; F337-Y339 AromaticContact CE2-CD2 3.79Å; F337-Y339 HydrophobicContact CE2-CD2 3.79Å; F337-Y339 HydrophobicContact CE2-CE2 4.29Å; F337-Y339 AromaticContact CE2-CG 3.73Å; F337-Y339 HydrophobicContact CE2-CG 3.73Å; F337-Y339 HydrophobicContact CZ-CD1 4.44Å; F337-Y339 AromaticContact CZ-CD2 3.22Å; F337-Y339 HydrophobicContact CZ-CD2 3.22Å; F337-Y339 AromaticContact CZ-CE2 3.88Å; F337-Y339 HydrophobicContact CZ-CE2 3.88Å; F337-Y339 AromaticContact CZ-CG 3.54Å; F337-Y339 HydrophobicContact CZ-CG 3.54Å; F337-Y339 PolarHBondContact O-N 3.02Å; F337-Y339 VanDerWaalsContact O-N 3.17Å; F337-N340 VanDerWaalsContact O-CB 3.29Å; F337-N340 WeakPolarHBondContact O-CB 3.37Å; F337-N340 PolarHBondContact O-N 3.34Å; F337-N340 PolarHBondContact O-ND2 3.32Å
338V97.3Very high97.3Very high4 Ų432.4 Ų32.42%0.02417%0.167CC..G310 helixtrans-61.9-26.1-175.6174.40000112.7F313 W332 E336 N340 Y341 P362 F443F313-V338 HydrophobicContact CE2-CB 3.88Å; F313-V338 HydrophobicContact CE2-CG1 3.93Å; F313-V338 HydrophobicContact CE2-CG2 4.39Å; F313-V338 HydrophobicContact CZ-CB 3.78Å; F313-V338 HydrophobicContact CZ-CG1 4.22Å; W332-V338 HydrophobicContact CB-CG2 3.64Å; W332-V338 HydrophobicContact CD2-CG1 4.18Å; W332-V338 HydrophobicContact CD2-CG2 3.8Å; W332-V338 HydrophobicContact CE3-CG1 4.27Å; W332-V338 HydrophobicContact CE3-CG2 4.09Å; W332-V338 HydrophobicContact CG-CG2 3.6Å; W332-V338 HydrophobicContact CZ2-CG1 4.47Å; W332-V338 HydrophobicContact CZ3-CG1 4.46Å; E336-V338 PolarHBondContact O-N 2.85Å; V338-N340 PolarHBondContact O-N 3.2Å; V338-N340 VanDerWaalsContact O-N 3.11Å; V338-Y341 WeakPolarHBondContact O-CD2 2.89Å; V338-Y341 PolarHBondContact O-N 2.94Å; V338-P362 HydrophobicContact CG2-CB 3.94Å; V338-P362 HydrophobicContact CG2-CG 3.81Å; V338-F443 HydrophobicContact CG1-CE1 3.63Å; V338-F443 HydrophobicContact CG1-CZ 4.15Å
339Y97.3Very high97.3Very high10 Ų1033.3 Ų33.34%0.03917%0.174CC..G310 helixtrans-62.7-18.7176.8-71.54.3000112.9H59 F61 F103 Y240 H242 F313 F337 Y341 L342H59-Y339 PolarHBondContact NE2-O 3.09Å; F61-Y339 HydrophobicContact CD2-CD2 4.02Å; F61-Y339 AromaticContact CD2-CE2 3.87Å; F61-Y339 HydrophobicContact CD2-CE2 3.87Å; F61-Y339 AromaticContact CE2-CD1 3.79Å; F61-Y339 HydrophobicContact CE2-CD1 3.79Å; F61-Y339 AromaticContact CE2-CD2 3.69Å; F61-Y339 HydrophobicContact CE2-CD2 3.69Å; F61-Y339 AromaticContact CE2-CE1 3.48Å; F61-Y339 HydrophobicContact CE2-CE1 3.48Å; F61-Y339 VanDerWaalsContact CE2-CE1 3.48Å; F61-Y339 AromaticContact CE2-CE2 3.44Å; F61-Y339 HydrophobicContact CE2-CE2 3.44Å; F61-Y339 VanDerWaalsContact CE2-CE2 3.44Å; F61-Y339 AromaticContact CE2-CG 3.89Å; F61-Y339 HydrophobicContact CE2-CG 3.89Å; F61-Y339 AromaticContact CE2-CZ 3.34Å; F61-Y339 HydrophobicContact CZ-CD1 4.44Å; F61-Y339 AromaticContact CZ-CE1 3.8Å; F61-Y339 HydrophobicContact CZ-CE1 3.8Å; F61-Y339 HydrophobicContact CZ-CE2 4.24Å; F61-Y339 AromaticContact CZ-CZ 3.72Å; F103-Y339 AromaticContact CE1-CD2 3.84Å; F103-Y339 HydrophobicContact CE1-CD2 3.84Å; F103-Y339 HydrophobicContact CE2-CD2 4.29Å; F103-Y339 AromaticContact CZ-CD2 3.53Å; F103-Y339 HydrophobicContact CZ-CD2 3.53Å; F103-Y339 HydrophobicContact CZ-CE2 4.28Å; F103-Y339 HydrophobicContact CZ-CG 4.49Å; Y240-Y339 HydrophobicContact CE1-CE2 4.22Å; Y240-Y339 AromaticContact CZ-CE2 3.98Å; Y240-Y339 WeakPolarHBondContact OH-CE2 3.27Å; Y240-Y339 PolarHBondContact OH-OH 3.37Å; H242-Y339 PolarHBondContact ND1-OH 2.96Å; F313-Y339 AromaticContact CD1-CE1 3.82Å; F313-Y339 HydrophobicContact CD1-CE1 3.82Å; F313-Y339 AromaticContact CD1-CZ 3.94Å; F313-Y339 AromaticContact CE1-CD1 3.7Å; F313-Y339 HydrophobicContact CE1-CD1 3.7Å; F313-Y339 AromaticContact CE1-CE1 3.06Å; F313-Y339 HydrophobicContact CE1-CE1 3.06Å; F313-Y339 HydrophobicContact CE1-CE2 4.34Å; F313-Y339 AromaticContact CE1-CZ 3.43Å; F313-Y339 VanDerWaalsContact CE1-CZ 3.43Å; F313-Y339 HydrophobicContact CE2-CD1 4.36Å; F313-Y339 AromaticContact CE2-CE1 3.96Å; F313-Y339 HydrophobicContact CE2-CE1 3.96Å; F313-Y339 AromaticContact CZ-CD1 3.42Å; F313-Y339 HydrophobicContact CZ-CD1 3.42Å; F313-Y339 VanDerWaalsContact CZ-CD1 3.42Å; F313-Y339 AromaticContact CZ-CE1 3.13Å; F313-Y339 HydrophobicContact CZ-CE1 3.13Å; F313-Y339 HydrophobicContact CZ-CG 4.49Å; F337-Y339 HydrophobicContact CD2-CG 4.43Å; F337-Y339 AromaticContact CE1-CD2 3.89Å; F337-Y339 HydrophobicContact CE1-CD2 3.89Å; F337-Y339 HydrophobicContact CE1-CG 4.09Å; F337-Y339 HydrophobicContact CE2-CD1 4.22Å; F337-Y339 AromaticContact CE2-CD2 3.79Å; F337-Y339 HydrophobicContact CE2-CD2 3.79Å; F337-Y339 HydrophobicContact CE2-CE2 4.29Å; F337-Y339 AromaticContact CE2-CG 3.73Å; F337-Y339 HydrophobicContact CE2-CG 3.73Å; F337-Y339 HydrophobicContact CZ-CD1 4.44Å; F337-Y339 AromaticContact CZ-CD2 3.22Å; F337-Y339 HydrophobicContact CZ-CD2 3.22Å; F337-Y339 AromaticContact CZ-CE2 3.88Å; F337-Y339 HydrophobicContact CZ-CE2 3.88Å; F337-Y339 AromaticContact CZ-CG 3.54Å; F337-Y339 HydrophobicContact CZ-CG 3.54Å; F337-Y339 PolarHBondContact O-N 3.02Å; F337-Y339 VanDerWaalsContact O-N 3.17Å; Y339-Y341 PolarHBondContact O-N 2.77Å; Y339-L342 HydrophobicContact CD1-CD1 3.58Å; Y339-L342 HydrophobicContact CE1-CD1 4.01Å; Y339-L342 HydrophobicContact CG-CD1 4.38Å; Y339-L342 PolarHBondContact O-N 2.79Å
340N96.3Very high97.2Very high66 Ų6637.6 Ų37.635%0.35320%0.197SC..G310 helixtrans-54.7-22.7169.4-74.3-26.8000113.5M277 F337 V338 W343M277-N340 HydrophobicContact CE-CB 4.35Å; M277-N340 WeakPolarHBondContact CE-OD1 3.42Å; F337-N340 VanDerWaalsContact O-CB 3.29Å; F337-N340 WeakPolarHBondContact O-CB 3.37Å; F337-N340 PolarHBondContact O-N 3.34Å; F337-N340 PolarHBondContact O-ND2 3.32Å; V338-N340 PolarHBondContact O-N 3.2Å; V338-N340 VanDerWaalsContact O-N 3.11Å; N340-W343 PolarHBondContact O-NE1 2.97Å
341Y96.7Very high97.1Very high28 Ų2837.8 Ų37.811%0.1120%0.198CC..G310 helixtrans-97.8-1.7-177.8-60.8-88.8000113.3E336 V338 Y339 A357 M360 A361 F443E336-Y341 VanDerWaalsContact CD-OH 3.26Å; E336-Y341 WeakPolarHBondContact OE1-CE2 3.22Å; E336-Y341 PolarHBondContact OE1-OH 2.9Å; E336-Y341 PolarHBondContact OE2-OH 3.12Å; V338-Y341 WeakPolarHBondContact O-CD2 2.89Å; V338-Y341 PolarHBondContact O-N 2.94Å; Y339-Y341 PolarHBondContact O-N 2.77Å; Y341-A357 WeakPolarHBondContact CE1-O 3.49Å; Y341-M360 HydrophobicContact CE1-CB 4.22Å; Y341-M360 VanDerWaalsContact OH-C 3.27Å; Y341-M360 PolarHBondContact OH-O 3.29Å; Y341-A361 HydrophobicContact CD1-CB 3.84Å; Y341-A361 HydrophobicContact CD2-CB 3.88Å; Y341-A361 HydrophobicContact CE1-CB 3.76Å; Y341-A361 HydrophobicContact CE2-CB 3.82Å; Y341-A361 HydrophobicContact CG-CB 3.91Å; Y341-A361 PolarHBondContact OH-N 3.16Å; Y341-F443 HydrophobicContact CD1-CE2 4.23Å; Y341-F443 HydrophobicContact CD2-CZ 4.38Å; Y341-F443 AromaticContact CG-CE2 3.87Å; Y341-F443 HydrophobicContact CG-CE2 3.87Å; Y341-F443 AromaticContact CG-CZ 3.98Å; Y341-F443 HydrophobicContact CG-CZ 3.98Å
342L97.6Very high97.1Very high18 Ų1843.7 Ų43.79%0.09423%0.225CC..  trans-105.521.4-173.4-56.4-177.6000113.7L60 F61 Y339 L347 F443L60-L342 HydrophobicContact CB-CB 4.21Å; L60-L342 VanDerWaalsContact CB-O 3.3Å; L60-L342 WeakPolarHBondContact CB-O 3.44Å; L60-L342 HydrophobicContact CD2-CB 4.36Å; L60-L342 HydrophobicContact CD2-CD1 4.31Å; L60-L342 HydrophobicContact CD2-CD2 4.49Å; L60-L342 PolarHBondContact N-O 3.45Å; F61-L342 HydrophobicContact CE2-CD1 3.97Å; F61-L342 HydrophobicContact CZ-CD1 4.09Å; Y339-L342 HydrophobicContact CD1-CD1 3.58Å; Y339-L342 HydrophobicContact CE1-CD1 4.01Å; Y339-L342 HydrophobicContact CG-CD1 4.38Å; Y339-L342 PolarHBondContact O-N 2.79Å; L342-L347 HydrophobicContact CB-CD1 4.46Å; L342-L347 HydrophobicContact CD2-CD2 4.3Å; L342-F443 HydrophobicContact CD2-CB 4.16Å; L342-F443 HydrophobicContact CD2-CD1 3.89Å; L342-F443 HydrophobicContact CD2-CG 4.06Å
343W98.1Very high97Very high68 Ų6848.3 Ų48.326%0.25825%0.247SC..BIsolated β-bridgetrans-63.6134.9165.9-64.1103.8000110.5H59 M277 N340 A345 N346 L347H59-W343 HydrophobicContact CB-CE3 4.06Å; H59-W343 HydrophobicContact CB-CZ3 4.04Å; H59-W343 AromaticContact CD2-CD2 3.94Å; H59-W343 AromaticContact CD2-CE3 3.95Å; M277-W343 HydrophobicContact CB-CH2 4.48Å; M277-W343 HydrophobicContact CG-CH2 4.33Å; M277-W343 HydrophobicContact CG-CZ2 3.94Å; N340-W343 PolarHBondContact O-NE1 2.97Å; W343-A345 PolarHBondContact O-N 3.44Å; W343-N346 WeakPolarHBondContact O-CB 3.07Å; W343-N346 PolarHBondContact O-N 2.59Å; W343-L347 PolarHBondContact O-N 2.96Å
344L98.3Very high96.9Very high2 Ų244.9 Ų44.91%0.0123%0.233CC..Hα-helixtrans-59.2-33-179.8-71166000112F16 F50 F57 Y58 H59 N346 L347 R348F16-L344 HydrophobicContact CB-CD2 4.1Å; F16-L344 HydrophobicContact CD1-CD2 4.12Å; F16-L344 HydrophobicContact CG-CD2 4.29Å; F50-L344 HydrophobicContact CD1-CD1 3.76Å; F50-L344 HydrophobicContact CD1-CD2 4.01Å; F50-L344 HydrophobicContact CE1-CD1 4.48Å; F50-L344 HydrophobicContact CE1-CD2 4Å; F57-L344 WeakPolarHBondContact O-CD1 3.47Å; Y58-L344 WeakPolarHBondContact O-CB 3.21Å; Y58-L344 PolarHBondContact O-N 3.23Å; H59-L344 WeakPolarHBondContact O-CD1 3.28Å; L344-N346 VanDerWaalsContact C-N 3.29Å; L344-N346 PolarHBondContact O-N 2.86Å; L344-L347 PolarHBondContact O-N 2.87Å; L344-R348 WeakPolarHBondContact O-CB 3.38Å; L344-R348 WeakPolarHBondContact O-CG 3.23Å; L344-R348 PolarHBondContact O-N 3.37Å
345A97.3Very high97Very high79 Ų7945 Ų4565%0.65323%0.226SC*.Hα-helixtrans-59.5-39.8174.100000112.3W343 A349W343-A345 PolarHBondContact O-N 3.44Å; A345-A349 PolarHBondContact O-N 2.87Å
346N96.4Very high97Very high64 Ų6449.5 Ų49.534%0.34225%0.246SC..Hα-helixtrans-73.5-45.4176.8-65.7-21.6000110.8W343 L344 R348 A349 V354W343-N346 WeakPolarHBondContact O-CB 3.07Å; W343-N346 PolarHBondContact O-N 2.59Å; L344-N346 VanDerWaalsContact C-N 3.29Å; L344-N346 PolarHBondContact O-N 2.86Å; N346-R348 VanDerWaalsContact C-N 3.26Å; N346-R348 PolarHBondContact O-N 2.82Å; N346-A349 WeakPolarHBondContact O-CB 3.46Å; N346-A349 PolarHBondContact O-N 3.46Å; N346-A349 VanDerWaalsContact O-N 3.15Å; N346-V354 WeakPolarHBondContact O-CG2 3.29Å
347L97.3Very high96.9Very high4 Ų448 Ų482%0.02125%0.245CC..Hα-helixtrans-67.8-25-178.9-64.2174.4000113.1Y12 F16 L60 L342 W343 L344 F443Y12-L347 WeakPolarHBondContact CD2-O 3.32Å; Y12-L347 VanDerWaalsContact CE2-O 3.24Å; Y12-L347 WeakPolarHBondContact CE2-O 3.22Å; F16-L347 HydrophobicContact CD2-CB 4.23Å; F16-L347 HydrophobicContact CE1-CB 4.4Å; F16-L347 HydrophobicContact CE1-CD1 4.07Å; F16-L347 HydrophobicContact CE2-CB 3.76Å; F16-L347 HydrophobicContact CZ-CB 3.85Å; F16-L347 HydrophobicContact CZ-CD1 4.13Å; F16-L347 HydrophobicContact CZ-CG 4.41Å; L60-L347 HydrophobicContact CB-CD1 4.02Å; L60-L347 HydrophobicContact CD1-CD1 4.24Å; L60-L347 HydrophobicContact CD2-CD1 4.01Å; L60-L347 HydrophobicContact CG-CD1 4.31Å; L342-L347 HydrophobicContact CB-CD1 4.46Å; L342-L347 HydrophobicContact CD2-CD2 4.3Å; W343-L347 PolarHBondContact O-N 2.96Å; L344-L347 PolarHBondContact O-N 2.87Å; L347-F443 HydrophobicContact CD2-CB 4.1Å
348R97.7Very high96.7Very high75 Ų7547.8 Ų47.828%0.28324%0.244SC..THydrogen-bonded Turntrans-93.20.3175.5-64.6171.7-1781630.3113.5K13 F16 F50 L344 N346K13-R348 WeakPolarHBondContact CD-O 3.49Å; K13-R348 WeakPolarHBondContact CE-O 3.37Å; K13-R348 PolarHBondContact NZ-O 3.42Å; F16-R348 HydrophobicContact CB-CG 4.01Å; F16-R348 HydrophobicContact CD2-CG 4.11Å; F16-R348 HydrophobicContact CG-CG 4.41Å; F16-R348 VanDerWaalsContact O-CZ 3.26Å; F16-R348 PolarHBondContact O-NE 2.94Å; F16-R348 VanDerWaalsContact O-NE 3.16Å; F16-R348 PolarHBondContact O-NH2 3.34Å; F50-R348 VanDerWaalsContact CG-NH2 3.34Å; L344-R348 WeakPolarHBondContact O-CB 3.38Å; L344-R348 WeakPolarHBondContact O-CG 3.23Å; L344-R348 PolarHBondContact O-N 3.37Å; N346-R348 VanDerWaalsContact C-N 3.26Å; N346-R348 PolarHBondContact O-N 2.82Å
349A97.8Very high96.6Very high18 Ų1852.1 Ų52.115%0.14927%0.265CS..SBendtrans-66.1169.117700000111.4Y12 K13 A345 N346 E353 V354Y12-A349 PolarHBondContact OH-O 2.9Å; K13-A349 VanDerWaalsContact CE-O 3.32Å; K13-A349 WeakPolarHBondContact CE-O 3.24Å; A345-A349 PolarHBondContact O-N 2.87Å; N346-A349 WeakPolarHBondContact O-CB 3.46Å; N346-A349 PolarHBondContact O-N 3.46Å; N346-A349 VanDerWaalsContact O-N 3.15Å; A349-E353 HydrophobicContact CB-CB 3.86Å; A349-V354 HydrophobicContact CB-CG2 4.12Å
350N97.3Very high96.3Very high90 Ų9058.5 Ų58.548%0.48130%0.297SS..  trans-71.4158.1173.7-66.8-37.5000110.9K13 E352 E353 V354K13-N350 PolarHBondContact NZ-OD1 3.37Å; N350-E352 VanDerWaalsContact C-N 3.31Å; N350-E352 PolarHBondContact O-N 2.69Å; N350-E353 PolarHBondContact N-OE2 3.03Å; N350-E353 WeakPolarHBondContact O-CA 3.45Å; N350-E353 WeakPolarHBondContact O-CB 3.29Å; N350-E353 PolarHBondContact O-N 2.87Å; N350-V354 PolarHBondContact O-N 3.05Å
351W96.9Very high96.2Very high6 Ų655.6 Ų55.62%0.02328%0.282CS..Hα-helixtrans-58.3-38.8-168.3177.3-122.9000114.4E6 H7 Y12 E353 V354 K355 N441 H442 I444E6-W351 PolarHBondContact OE2-NE1 3.19Å; H7-W351 HydrophobicContact CB-CD2 4.06Å; H7-W351 HydrophobicContact CB-CE3 4.24Å; H7-W351 HydrophobicContact CB-CG 4.28Å; H7-W351 VanDerWaalsContact O-CB 3.29Å; H7-W351 WeakPolarHBondContact O-CB 3.3Å; Y12-W351 HydrophobicContact CE1-CB 4.34Å; Y12-W351 AromaticContact CE1-CE3 3.99Å; Y12-W351 HydrophobicContact CE1-CE3 3.99Å; Y12-W351 VanDerWaalsContact OH-CA 3.26Å; Y12-W351 WeakPolarHBondContact OH-CA 3.41Å; Y12-W351 PolarHBondContact OH-N 3.39Å; W351-E353 VanDerWaalsContact C-N 3.31Å; W351-E353 PolarHBondContact O-N 2.79Å; W351-V354 HydrophobicContact CE3-CB 4.18Å; W351-V354 HydrophobicContact CE3-CG1 4.16Å; W351-V354 HydrophobicContact CZ3-CB 4.48Å; W351-V354 HydrophobicContact CZ3-CG1 3.99Å; W351-V354 PolarHBondContact O-N 2.86Å; W351-K355 HydrophobicContact CD2-CD 4.38Å; W351-K355 HydrophobicContact CD2-CG 4.16Å; W351-K355 HydrophobicContact CE3-CG 4.42Å; W351-K355 HydrophobicContact CH2-CD 4.48Å; W351-K355 HydrophobicContact CH2-CG 3.98Å; W351-K355 HydrophobicContact CZ2-CD 3.71Å; W351-K355 HydrophobicContact CZ2-CG 3.7Å; W351-K355 HydrophobicContact CZ3-CG 4.33Å; W351-K355 WeakPolarHBondContact O-CG 3.25Å; W351-K355 PolarHBondContact O-N 2.65Å; W351-N441 HydrophobicContact CH2-CB 4.46Å; W351-H442 HydrophobicContact CH2-CB 4.24Å; W351-H442 AromaticContact CH2-ND1 3.83Å; W351-H442 HydrophobicContact CZ3-CB 4.39Å; W351-I444 HydrophobicContact CE3-CG1 4.46Å; W351-I444 HydrophobicContact CZ3-CB 4.37Å; W351-I444 HydrophobicContact CZ3-CG1 3.88Å
352E96.9Very high96.3Very high124 Ų12454.7 Ų54.758%0.57928%0.279SS*.Hα-helixtrans-63.7-35.2174.8-65.9-54.6139.700113.1N350 K355 K356N350-E352 VanDerWaalsContact C-N 3.31Å; N350-E352 PolarHBondContact O-N 2.69Å; E352-K355 VanDerWaalsContact CD-CE 3.46Å; E352-K355 WeakPolarHBondContact OE1-CE 3.07Å; E352-K355 IonicContact OE1-NZ 2.65Å; E352-K355 PolarHBondContact OE1-NZ 3.4Å; E352-K355 WeakPolarHBondContact OE2-CE 3.45Å; E352-K355 IonicContact OE2-NZ 3.7Å; E352-K355 PolarHBondContact OE2-NZ 2.82Å; E352-K356 WeakPolarHBondContact O-CB 3.2Å; E352-K356 PolarHBondContact O-N 2.85Å
353E96.8Very high96.3Very high109 Ų10955.3 Ų55.351%0.50928%0.282SS..Hα-helixtrans-73.6-41.3178.3-64.2166.4156.800111A349 N350 W351 K356 A357A349-E353 HydrophobicContact CB-CB 3.86Å; N350-E353 PolarHBondContact N-OE2 3.03Å; N350-E353 WeakPolarHBondContact O-CA 3.45Å; N350-E353 WeakPolarHBondContact O-CB 3.29Å; N350-E353 PolarHBondContact O-N 2.87Å; W351-E353 VanDerWaalsContact C-N 3.31Å; W351-E353 PolarHBondContact O-N 2.79Å; E353-K356 PolarHBondContact O-N 3.3Å; E353-A357 WeakPolarHBondContact O-CB 3.39Å; E353-A357 PolarHBondContact O-N 2.87Å
354V96.8Very high96.3Very high6 Ų652.3 Ų52.34%0.03627%0.271CS..Hα-helixtrans-56.4-51.1172.9172.80000110.3Y12 N346 A349 N350 W351 K356 A357 A358 H442 I444Y12-V354 HydrophobicContact CE2-CG2 4.2Å; Y12-V354 WeakPolarHBondContact OH-CG2 3.4Å; N346-V354 WeakPolarHBondContact O-CG2 3.29Å; A349-V354 HydrophobicContact CB-CG2 4.12Å; N350-V354 PolarHBondContact O-N 3.05Å; W351-V354 HydrophobicContact CE3-CB 4.18Å; W351-V354 HydrophobicContact CE3-CG1 4.16Å; W351-V354 HydrophobicContact CZ3-CB 4.48Å; W351-V354 HydrophobicContact CZ3-CG1 3.99Å; W351-V354 PolarHBondContact O-N 2.86Å; V354-K356 PolarHBondContact O-N 3.36Å; V354-A357 PolarHBondContact O-N 2.85Å; V354-A358 WeakPolarHBondContact O-CB 3.43Å; V354-A358 PolarHBondContact O-N 3.38Å; V354-H442 HydrophobicContact CG1-CB 4.26Å; V354-H442 WeakPolarHBondContact CG1-O 3.43Å; V354-I444 HydrophobicContact CG1-CD1 4.26Å; V354-I444 HydrophobicContact CG1-CG1 3.94Å
355K96.2Very high96.3Very high30 Ų3052.8 Ų52.813%0.1327%0.273CS..Hα-helixtrans-57.3-48.9176.7-74.4-174-65.4-177.80111.4E6 W351 E352 A357 A358 M359E6-K355 IonicContact OE1-NZ 3.65Å; E6-K355 IonicContact OE2-NZ 2.59Å; E6-K355 PolarHBondContact OE2-NZ 3.36Å; W351-K355 HydrophobicContact CD2-CD 4.38Å; W351-K355 HydrophobicContact CD2-CG 4.16Å; W351-K355 HydrophobicContact CE3-CG 4.42Å; W351-K355 HydrophobicContact CH2-CD 4.48Å; W351-K355 HydrophobicContact CH2-CG 3.98Å; W351-K355 HydrophobicContact CZ2-CD 3.71Å; W351-K355 HydrophobicContact CZ2-CG 3.7Å; W351-K355 HydrophobicContact CZ3-CG 4.33Å; W351-K355 WeakPolarHBondContact O-CG 3.25Å; W351-K355 PolarHBondContact O-N 2.65Å; E352-K355 VanDerWaalsContact CD-CE 3.46Å; E352-K355 WeakPolarHBondContact OE1-CE 3.07Å; E352-K355 IonicContact OE1-NZ 2.65Å; E352-K355 PolarHBondContact OE1-NZ 3.4Å; E352-K355 WeakPolarHBondContact OE2-CE 3.45Å; E352-K355 IonicContact OE2-NZ 3.7Å; E352-K355 PolarHBondContact OE2-NZ 2.82Å; K355-A357 VanDerWaalsContact C-N 3.35Å; K355-A357 PolarHBondContact O-N 3.11Å; K355-A358 PolarHBondContact O-N 2.79Å; K355-M359 WeakPolarHBondContact O-CG 3.4Å; K355-M359 PolarHBondContact O-N 2.75Å; K355-M359 VanDerWaalsContact O-N 3.12Å
356K95.6Very high96.4Very high165 Ų16549 Ų4972%0.71724%0.242SC*.Hα-helixtrans-59.7-43.5-179.1-174.5-178.6178-1750112E352 E353 V354 M359E352-K356 WeakPolarHBondContact O-CB 3.2Å; E352-K356 PolarHBondContact O-N 2.85Å; E353-K356 PolarHBondContact O-N 3.3Å; V354-K356 PolarHBondContact O-N 3.36Å; K356-M359 PolarHBondContact O-N 2.88Å
357A93.5Very high96.5Very high35 Ų3547.1 Ų47.129%0.28923%0.23SC..Hα-helixtrans-63.1-45.9177.100000111.3Y341 E353 V354 K355 M359 M360Y341-A357 WeakPolarHBondContact CE1-O 3.49Å; E353-A357 WeakPolarHBondContact O-CB 3.39Å; E353-A357 PolarHBondContact O-N 2.87Å; V354-A357 PolarHBondContact O-N 2.85Å; K355-A357 VanDerWaalsContact C-N 3.35Å; K355-A357 PolarHBondContact O-N 3.11Å; A357-M359 PolarHBondContact O-N 3.4Å; A357-M360 PolarHBondContact O-N 2.67Å
358A93.9Very high96.6Very high2 Ų247 Ų472%0.01723%0.23CC..Hα-helixtrans-69.6-14-17900000114.3V354 K355 M360 A361 R414 H442 F443V354-A358 WeakPolarHBondContact O-CB 3.43Å; V354-A358 PolarHBondContact O-N 3.38Å; K355-A358 PolarHBondContact O-N 2.79Å; A358-M360 PolarHBondContact O-N 3.49Å; A358-A361 WeakPolarHBondContact O-CB 3.45Å; A358-A361 PolarHBondContact O-N 2.84Å; A358-A361 VanDerWaalsContact O-N 3.17Å; A358-R414 PolarHBondContact O-NH1 3.27Å; A358-H442 HydrophobicContact CB-CB 3.65Å; A358-F443 HydrophobicContact CB-CD2 3.93Å; A358-F443 HydrophobicContact CB-CE2 3.8Å
359M93.4Very high96.6Very high96 Ų9643.5 Ų43.547%0.47322%0.216SC..THydrogen-bonded Turntrans-67-23.4175.5-75.4-55.8-58.100113.6K355 K356 A357 R414K355-M359 WeakPolarHBondContact O-CG 3.4Å; K355-M359 PolarHBondContact O-N 2.75Å; K355-M359 VanDerWaalsContact O-N 3.12Å; K356-M359 PolarHBondContact O-N 2.88Å; A357-M359 PolarHBondContact O-N 3.4Å; M359-R414 VanDerWaalsContact C-NH1 3.3Å; M359-R414 PolarHBondContact O-NH1 3.38Å; M359-R414 HydrophobicContact SD-CG 4.34Å
360M91.4Very high96.7Very high144 Ų14442.7 Ų42.771%0.70921%0.21SC*.SBendtrans-85.5-17.5174.1-61.9-59.9109.100112.5Y341 A357 A358Y341-M360 HydrophobicContact CE1-CB 4.22Å; Y341-M360 VanDerWaalsContact OH-C 3.27Å; Y341-M360 PolarHBondContact OH-O 3.29Å; A357-M360 PolarHBondContact O-N 2.67Å; A358-M360 PolarHBondContact O-N 3.49Å
361A95.1Very high96.8Very high4 Ų438.5 Ų38.53%0.03319%0.187CC..SBendtrans-64.7158.7-174.800000113.8Y341 A358 R414 F443Y341-A361 HydrophobicContact CD1-CB 3.84Å; Y341-A361 HydrophobicContact CD2-CB 3.88Å; Y341-A361 HydrophobicContact CE1-CB 3.76Å; Y341-A361 HydrophobicContact CE2-CB 3.82Å; Y341-A361 HydrophobicContact CG-CB 3.91Å; Y341-A361 PolarHBondContact OH-N 3.16Å; A358-A361 WeakPolarHBondContact O-CB 3.45Å; A358-A361 PolarHBondContact O-N 2.84Å; A358-A361 VanDerWaalsContact O-N 3.17Å; A361-R414 PolarHBondContact O-NH1 2.83Å; A361-R414 PolarHBondContact O-NH2 2.9Å; A361-F443 HydrophobicContact CB-CE2 3.82Å; A361-F443 HydrophobicContact CB-CZ 3.6Å
362P97.5Very high96.8Very high9 Ų938.3 Ų38.36%0.05819%0.186CC..PPolyproline II helixtrans-47.7141161.6-33.140.5000112.4W332 K333 E336 V338W332-P362 HydrophobicContact CB-CB 3.81Å; W332-P362 HydrophobicContact CE3-CB 4.31Å; K333-P362 WeakPolarHBondContact O-CA 3.17Å; K333-P362 WeakPolarHBondContact O-CB 3.48Å; E336-P362 HydrophobicContact CB-CG 4.1Å; V338-P362 HydrophobicContact CG2-CB 3.94Å; V338-P362 HydrophobicContact CG2-CG 3.81Å
363Q98.2Very high96.5Very high32 Ų3234.1 Ų34.115%0.1517%0.168CC..EExtended strand (participates in β ladder)trans-84.7125.3178.1170.958.14800109.6K333 G412K333-Q363 HydrophobicContact CB-CB 4.4Å; K333-Q363 HydrophobicContact CD-CB 4.36Å; K333-Q363 HydrophobicContact CD-CG 4.42Å; K333-Q363 WeakPolarHBondContact CG-O 2.97Å; K333-Q363 PolarHBondContact N-O 2.84Å; Q363-G412 PolarHBondContact NE2-O 2.96Å
364P98.4Very high96.2Very high4 Ų434.6 Ų34.63%0.02617%0.174CC..EExtended strand (participates in β ladder)trans-71.6146.717728.5-35.6000112.2S331 W332 A416S331-P364 CarbonylContact O-C 3.4Å; S331-P364 VanDerWaalsContact O-CA 3.31Å; S331-P364 WeakPolarHBondContact O-CA 3.45Å; W332-P364 HydrophobicContact CD2-CB 4.13Å; W332-P364 HydrophobicContact CE3-CB 3.84Å; W332-P364 HydrophobicContact CE3-CG 4.28Å; W332-P364 HydrophobicContact CH2-CB 3.98Å; W332-P364 HydrophobicContact CH2-CG 4.21Å; W332-P364 HydrophobicContact CZ2-CB 4.25Å; W332-P364 HydrophobicContact CZ3-CB 3.76Å; W332-P364 HydrophobicContact CZ3-CG 3.86Å; P364-A416 HydrophobicContact CB-CB 3.53Å; P364-A416 HydrophobicContact CG-CB 3.75Å
365E98.4Very high95.7Very high12 Ų1236 Ų366%0.05618%0.183CC..EExtended strand (participates in β ladder)trans-157.1137.9176-171.5163.180.900110.8S331 K333 R367 V408 F410 S411S331-E365 WeakPolarHBondContact CA-O 3.4Å; S331-E365 PolarHBondContact N-O 2.86Å; S331-E365 PolarHBondContact O-N 3.37Å; S331-E365 VanDerWaalsContact O-O 3.13Å; S331-E365 PolarHBondContact OG-O 2.76Å; K333-E365 WeakPolarHBondContact CE-OE1 3.39Å; K333-E365 WeakPolarHBondContact CE-OE2 3.42Å; K333-E365 VanDerWaalsContact NZ-CD 3.35Å; K333-E365 IonicContact NZ-OE1 3.02Å; K333-E365 PolarHBondContact NZ-OE1 3.38Å; K333-E365 IonicContact NZ-OE2 3.21Å; K333-E365 PolarHBondContact NZ-OE2 3.02Å; E365-R367 HydrophobicContact CB-CG 4.42Å; E365-R367 HydrophobicContact CG-CG 3.98Å; E365-R367 IonicContact OE1-CZ 2.72Å; E365-R367 VanDerWaalsContact OE1-CZ 3.24Å; E365-R367 IonicContact OE1-NE 2.67Å; E365-R367 PolarHBondContact OE1-NE 2.87Å; E365-R367 IonicContact OE1-NH2 2.65Å; E365-R367 PolarHBondContact OE1-NH2 3.3Å; E365-V408 VanDerWaalsContact CD-CG2 3.4Å; E365-V408 HydrophobicContact CG-CB 4.42Å; E365-V408 HydrophobicContact CG-CG1 3.54Å; E365-V408 HydrophobicContact CG-CG2 4.14Å; E365-V408 VanDerWaalsContact OE1-CG2 3.29Å; E365-V408 WeakPolarHBondContact OE1-CG2 3.23Å; E365-F410 WeakPolarHBondContact CA-O 3.48Å; E365-F410 WeakPolarHBondContact CG-O 3.34Å; E365-S411 WeakPolarHBondContact OE2-CB 3.11Å; E365-S411 PolarHBondContact OE2-OG 2.9Å
366V98.9Very high95.3Very high1 Ų139.6 Ų39.61%0.00620%0.2CC..EExtended strand (participates in β ladder)trans-87.5126168.2-177.80000109.1I316 L329 L409 F410 F417 L451I316-V366 HydrophobicContact CD1-CG1 3.4Å; I316-V366 HydrophobicContact CD1-CG2 4.44Å; L329-V366 VanDerWaalsContact O-CA 3.31Å; L329-V366 WeakPolarHBondContact O-CA 3.33Å; V366-L409 HydrophobicContact CB-CB 4.24Å; V366-L409 HydrophobicContact CG1-CB 3.91Å; V366-L409 HydrophobicContact CG1-CD1 4.05Å; V366-L409 HydrophobicContact CG1-CG 4.4Å; V366-L409 PolarHBondContact O-N 2.64Å; V366-F410 HydrophobicContact CB-CB 3.94Å; V366-F410 HydrophobicContact CG2-CB 3.91Å; V366-F410 HydrophobicContact CG2-CD1 4.23Å; V366-F410 PolarHBondContact N-O 3.21Å; V366-F410 PolarHBondContact O-N 2.96Å; V366-F417 HydrophobicContact CG2-CB 3.7Å; V366-F417 HydrophobicContact CG2-CD1 3.74Å; V366-F417 HydrophobicContact CG2-CG 3.97Å; V366-L451 HydrophobicContact CG1-CD2 4.17Å
367R98.8Very high94.7Very high23 Ų2340 Ų409%0.08720%0.202CC..EExtended strand (participates in β ladder)trans-127.3132.7-172.7-68.6-178.6172.1-167.5-7.3111.6D328 L329 S331 E365 Y369 P406D328-R367 CarbonylContact C-O 3.58Å; D328-R367 WeakPolarHBondContact CA-O 3.36Å; L329-R367 PolarHBondContact N-O 3.04Å; L329-R367 PolarHBondContact O-N 3.04Å; S331-R367 WeakPolarHBondContact OG-CD 3.43Å; S331-R367 WeakPolarHBondContact OG-CG 3.4Å; E365-R367 HydrophobicContact CB-CG 4.42Å; E365-R367 HydrophobicContact CG-CG 3.98Å; E365-R367 IonicContact OE1-CZ 2.72Å; E365-R367 VanDerWaalsContact OE1-CZ 3.24Å; E365-R367 IonicContact OE1-NE 2.67Å; E365-R367 PolarHBondContact OE1-NE 2.87Å; E365-R367 IonicContact OE1-NH2 2.65Å; E365-R367 PolarHBondContact OE1-NH2 3.3Å; R367-Y369 HydrophobicContact CB-CD2 4.19Å; R367-Y369 HydrophobicContact CB-CE2 3.72Å; R367-Y369 PolarHBondContact NH1-OH 3.39Å; R367-P406 HydrophobicContact CB-CB 3.84Å; R367-P406 HydrophobicContact CG-CB 4.04Å; R367-P406 HydrophobicContact CG-CG 4.22Å
368R98.9Very high94.3Very high3 Ų345.7 Ų45.71%0.01122%0.222CC..EExtended strand (participates in β ladder)trans-96.6125.1166.6173164.4-71159.60.8109.8V326 F327 D328 V370 P406 E407 L409 V453V326-R368 HydrophobicContact CG1-CG 3.8Å; F327-R368 WeakPolarHBondContact O-CA 3.17Å; D328-R368 WeakPolarHBondContact OD1-CA 3.31Å; D328-R368 WeakPolarHBondContact OD1-CB 3.37Å; D328-R368 VanDerWaalsContact OD1-CG 3.26Å; D328-R368 WeakPolarHBondContact OD1-CG 3.36Å; D328-R368 IonicContact OD1-CZ 3.24Å; D328-R368 IonicContact OD1-NE 3.93Å; D328-R368 PolarHBondContact OD1-NE 2.8Å; D328-R368 IonicContact OD1-NH2 3.78Å; D328-R368 PolarHBondContact OD1-NH2 2.58Å; D328-R368 IonicContact OD2-CZ 3.4Å; D328-R368 IonicContact OD2-NE 3.94Å; D328-R368 IonicContact OD2-NH2 2.73Å; D328-R368 PolarHBondContact OD2-NH2 3.29Å; R368-V370 HydrophobicContact CG-CG2 4.39Å; R368-P406 CarbonylContact O-C 3.54Å; R368-P406 VanDerWaalsContact O-CA 3.23Å; R368-P406 WeakPolarHBondContact O-CA 3.47Å; R368-E407 HydrophobicContact CB-CB 4.16Å; R368-E407 PolarHBondContact N-O 3.03Å; R368-E407 PolarHBondContact O-N 2.7Å; R368-L409 HydrophobicContact CB-CD1 4.07Å; R368-L409 HydrophobicContact CB-CD2 4.15Å; R368-L409 HydrophobicContact CB-CG 4.07Å; R368-V453 PolarHBondContact NH1-O 3.3Å; R368-V453 VanDerWaalsContact NH2-CG2 3.3Å; R368-V453 PolarHBondContact NH2-O 3.23Å
369Y98.9Very high93.9Very high1 Ų149 Ų490%0.00424%0.237CC..EExtended strand (participates in β ladder)trans-112.6152.5170.7-72.8-87.7000109.9F290 I310 F327 L329 R367 L404 P406F290-Y369 HydrophobicContact CE1-CD1 4.33Å; F290-Y369 HydrophobicContact CE1-CD2 4.35Å; F290-Y369 HydrophobicContact CE1-CE1 4.35Å; F290-Y369 HydrophobicContact CE1-CE2 4.38Å; F290-Y369 HydrophobicContact CE1-CG 4.32Å; F290-Y369 HydrophobicContact CE2-CE1 4.4Å; F290-Y369 HydrophobicContact CZ-CD1 4Å; F290-Y369 AromaticContact CZ-CE1 3.71Å; F290-Y369 HydrophobicContact CZ-CE1 3.71Å; F290-Y369 HydrophobicContact CZ-CE2 4.35Å; F290-Y369 HydrophobicContact CZ-CG 4.44Å; F290-Y369 AromaticContact CZ-CZ 3.9Å; I310-Y369 HydrophobicContact CD1-CE2 4.23Å; F327-Y369 AromaticContact CE2-CD2 3.98Å; F327-Y369 HydrophobicContact CE2-CD2 3.98Å; F327-Y369 HydrophobicContact CE2-CG 4.02Å; F327-Y369 HydrophobicContact CZ-CD2 4.36Å; F327-Y369 AromaticContact CZ-CG 3.93Å; F327-Y369 HydrophobicContact CZ-CG 3.93Å; F327-Y369 PolarHBondContact N-O 3.49Å; F327-Y369 PolarHBondContact O-N 3.15Å; L329-Y369 HydrophobicContact CD1-CD2 4.04Å; L329-Y369 HydrophobicContact CD1-CE2 4.1Å; R367-Y369 HydrophobicContact CB-CD2 4.19Å; R367-Y369 HydrophobicContact CB-CE2 3.72Å; R367-Y369 PolarHBondContact NH1-OH 3.39Å; Y369-L404 HydrophobicContact CD1-CB 3.92Å; Y369-L404 HydrophobicContact CD1-CD1 4.34Å; Y369-L404 HydrophobicContact CE1-CB 4.26Å; Y369-P406 HydrophobicContact CD1-CB 4.08Å; Y369-P406 HydrophobicContact CD2-CB 4.26Å; Y369-P406 HydrophobicContact CE1-CB 3.72Å; Y369-P406 HydrophobicContact CE1-CG 4.06Å; Y369-P406 HydrophobicContact CE2-CB 3.9Å; Y369-P406 HydrophobicContact CG-CB 4.34Å
370V98.8Very high93.8Very high1 Ų149.4 Ų49.41%0.00624%0.238CC..EExtended strand (participates in β ladder)trans-133.6121.6-179-177.20000108.9F324 I325 V326 R368 V385 L387 T390 A392F324-V370 HydrophobicContact CB-CG1 3.78Å; F324-V370 HydrophobicContact CD1-CG1 3.72Å; F324-V370 HydrophobicContact CG-CG1 3.98Å; I325-V370 CarbonylContact O-C 3.52Å; I325-V370 WeakPolarHBondContact O-CA 3.34Å; V326-V370 HydrophobicContact CG1-CG2 4.29Å; V326-V370 HydrophobicContact CG2-CG1 4.41Å; V326-V370 HydrophobicContact CG2-CG2 4.22Å; R368-V370 HydrophobicContact CG-CG2 4.39Å; V370-V385 HydrophobicContact CB-CG1 4.28Å; V370-V385 HydrophobicContact CB-CG2 4Å; V370-V385 HydrophobicContact CG1-CG1 3.92Å; V370-V385 HydrophobicContact CG1-CG2 3.92Å; V370-L387 HydrophobicContact CG1-CD1 3.97Å; V370-T390 HydrophobicContact CG2-CG2 4.1Å; V370-A392 HydrophobicContact CB-CB 4.18Å; V370-A392 HydrophobicContact CG2-CB 3.7Å
371I98.4Very high93.8Very high1 Ų145.3 Ų45.31%0.00523%0.233CC..EExtended strand (participates in β ladder)trans-106.9121.4178.7-74.6169.7000109.5F290 V292 F305 F324 I325 F327 L404F290-I371 HydrophobicContact CB-CD1 4.06Å; V292-I371 HydrophobicContact CG2-CD1 3.65Å; V292-I371 HydrophobicContact CG2-CG2 4.11Å; F305-I371 HydrophobicContact CD1-CG1 4.3Å; F305-I371 HydrophobicContact CD1-CG2 4.23Å; F305-I371 HydrophobicContact CD2-CG2 4.37Å; F305-I371 HydrophobicContact CE1-CG2 3.66Å; F305-I371 HydrophobicContact CE2-CG2 3.81Å; F305-I371 HydrophobicContact CG-CD1 4.49Å; F305-I371 HydrophobicContact CG-CG1 4.41Å; F305-I371 HydrophobicContact CZ-CG2 3.44Å; F305-I371 VanDerWaalsContact CZ-CG2 3.44Å; F324-I371 CarbonylContact C-O 3.53Å; F324-I371 VanDerWaalsContact CA-O 3.25Å; F324-I371 WeakPolarHBondContact CA-O 3.35Å; I325-I371 HydrophobicContact CB-CB 4.4Å; I325-I371 PolarHBondContact N-O 2.84Å; I325-I371 PolarHBondContact O-N 3.17Å; F327-I371 HydrophobicContact CE1-CD1 3.54Å; F327-I371 HydrophobicContact CE1-CG1 3.87Å; F327-I371 HydrophobicContact CZ-CD1 4.07Å; I371-L404 HydrophobicContact CD1-CD1 4.29Å; I371-L404 HydrophobicContact CG1-CD1 3.74Å
372P97.1Very high93.7Very high2 Ų251.4 Ų51.41%0.01326%0.259CS..EExtended strand (participates in β ladder)trans-70.3133.7169.328.9-33.1000110.9F305 F324 V375 L384 A394F305-P372 HydrophobicContact CE1-CG 4.27Å; F324-P372 HydrophobicContact CD1-CB 4.01Å; F324-P372 HydrophobicContact CE1-CB 3.82Å; P372-V375 HydrophobicContact CB-CG2 4.01Å; P372-V375 HydrophobicContact CG-CG2 3.86Å; P372-L384 HydrophobicContact CB-CB 4.25Å; P372-L384 HydrophobicContact CG-CB 4.02Å; P372-L384 HydrophobicContact CG-CD1 3.93Å; P372-A394 HydrophobicContact CG-CB 4.13Å
373L91.9Very high93.7Very high36 Ų3654.7 Ų54.719%0.18828%0.275CS..SBendtrans-85.8-38.7174.7-66.7171.4000112.2Y250 G323 I325Y250-L373 HydrophobicContact CD1-CD2 4.23Å; Y250-L373 HydrophobicContact CE1-CD2 3.72Å; Y250-L373 HydrophobicContact CE2-CD1 3.71Å; Y250-L373 HydrophobicContact CE2-CD2 4.22Å; G323-L373 VanDerWaalsContact O-CB 3.24Å; G323-L373 WeakPolarHBondContact O-CB 3.31Å; G323-L373 WeakPolarHBondContact O-CG 3.48Å; G323-L373 PolarHBondContact O-N 2.66Å; I325-L373 HydrophobicContact CD1-CD2 3.63Å; I325-L373 HydrophobicContact CD1-CG 4.5Å; I325-L373 HydrophobicContact CG1-CD1 4.3Å; I325-L373 HydrophobicContact CG1-CD2 3.86Å; I325-L373 HydrophobicContact CG1-CG 4.2Å
374D89.1Confident93.7Very high120 Ų12053.9 Ų53.964%0.64227%0.272SS*.SBendtrans-98.3113.2177.2-68.8-40000109.5
375V88.3Confident93.6Very high35 Ų3554.4 Ų54.421%0.21228%0.275CS..  trans-127.5116.9-172176.10000109.8L303 P372 L384 M396 I402L303-V375 HydrophobicContact CD1-CB 4.34Å; L303-V375 HydrophobicContact CD1-CG2 4.09Å; P372-V375 HydrophobicContact CB-CG2 4.01Å; P372-V375 HydrophobicContact CG-CG2 3.86Å; V375-L384 HydrophobicContact CG1-CD1 4.28Å; V375-L384 HydrophobicContact CG2-CD1 4.47Å; V375-M396 HydrophobicContact CB-CE 4.47Å; V375-M396 HydrophobicContact CG1-CE 2.98Å; V375-I402 HydrophobicContact CG1-CD1 3.94Å; V375-I402 HydrophobicContact CG2-CD1 4.03Å
376H87.8Confident93.5Very high106 Ų10658.1 Ų58.149%0.49130%0.303SS..  trans-112.1139.7-178.5-60.4-70000111.9E378 E379H376-E378 WeakPolarHBondContact CB-OE2 3.4Å; H376-E378 PolarHBondContact O-N 3.3Å; H376-E379 HydrophobicContact CB-CG 4.28Å; H376-E379 IonicContact CD2-OE2 2.96Å; H376-E379 PolarHBondContact O-N 2.6Å
377K81.9Confident93.5Very high174 Ų17458.4 Ų58.476%0.75730%0.304SS*.G310 helixtrans-66.6-26.1-175.5-73.6-175.3177.21800112.6E379 Q380K377-E379 PolarHBondContact O-N 3.05Å; K377-Q380 WeakPolarHBondContact O-CB 3.47Å; K377-Q380 PolarHBondContact O-N 3.11Å
378E84.7Confident93.4Very high154 Ų15463 Ų6372%0.7234%0.337SS*.G310 helixtrans-66.1-13.3178.5-6075.2-163.800112.5H376H376-E378 WeakPolarHBondContact CB-OE2 3.4Å; H376-E378 PolarHBondContact O-N 3.3Å
379E85.3Confident93.3Very high72 Ų7266.5 Ų66.534%0.33635%0.351SS..G310 helixtrans-98.47.8-178.2-55.6-176.9114.200113.1H376 K377 G381 K382 L384H376-E379 HydrophobicContact CB-CG 4.28Å; H376-E379 IonicContact CD2-OE2 2.96Å; H376-E379 PolarHBondContact O-N 2.6Å; K377-E379 PolarHBondContact O-N 3.05Å; E379-G381 PolarHBondContact O-N 2.68Å; E379-K382 WeakPolarHBondContact O-CB 3.47Å; E379-K382 PolarHBondContact O-N 2.84Å; E379-K382 VanDerWaalsContact O-N 3.11Å; E379-L384 HydrophobicContact CB-CD2 3.48Å; E379-L384 VanDerWaalsContact CB-CD2 3.48Å; E379-L384 HydrophobicContact CG-CD2 4.48Å
380Q91.2Very high93.3Very high103 Ų10367.3 Ų67.348%0.48136%0.356SS..THydrogen-bonded Turntrans-50.9135177.5-170.1-171.5-48.800112.3K377 K382 M396 A398K377-Q380 WeakPolarHBondContact O-CB 3.47Å; K377-Q380 PolarHBondContact O-N 3.11Å; Q380-K382 VanDerWaalsContact C-N 3.25Å; Q380-K382 PolarHBondContact O-N 2.97Å; Q380-M396 HydrophobicContact CB-SD 4.49Å; Q380-A398 VanDerWaalsContact NE2-CA 3.34Å
381G92.1Very high93.3Very high59 Ų5971.9 Ų71.961%0.60838%0.384SS*.THydrogen-bonded Turntrans77.9-1.1179.800000115.3E379 M396E379-G381 PolarHBondContact O-N 2.68Å; G381-M396 PolarHBondContact N-O 2.82Å
382K94.2Very high93.3Very high132 Ų13271.9 Ų71.957%0.57438%0.384SS*.SBendtrans-99.8158173.7-59.2175.3-175.6166.40110.7E379 Q380 L384E379-K382 WeakPolarHBondContact O-CB 3.47Å; E379-K382 PolarHBondContact O-N 2.84Å; E379-K382 VanDerWaalsContact O-N 3.11Å; Q380-K382 VanDerWaalsContact C-N 3.25Å; Q380-K382 PolarHBondContact O-N 2.97Å; K382-L384 PolarHBondContact O-N 3.22Å
383N96.8Very high93.4Very high77 Ų7773.8 Ų73.841%0.41240%0.396SS..BIsolated β-bridgetrans-71.7119.6164.7-179.222000109V385 T393 A394N383-V385 PolarHBondContact ND2-O 2.85Å; N383-V385 WeakPolarHBondContact OD1-CB 3.33Å; N383-V385 PolarHBondContact OD1-N 3.27Å; N383-T393 VanDerWaalsContact OD1-CA 3.3Å; N383-T393 WeakPolarHBondContact OD1-CA 3.32Å; N383-T393 WeakPolarHBondContact OD1-CB 3.26Å; N383-A394 PolarHBondContact OD1-N 3.4Å; N383-A394 PolarHBondContact OD1-O 3.01Å
384L97.1Very high93.7Very high16 Ų1672.1 Ų72.18%0.08439%0.387CS..  trans-80.8-17.6178.8-55.1179.1000112.2F324 P372 V375 E379 K382 S386 A394 M396 I402F324-L384 VanDerWaalsContact CE1-O 3.29Å; F324-L384 WeakPolarHBondContact CE1-O 3.16Å; F324-L384 WeakPolarHBondContact CZ-O 3.23Å; P372-L384 HydrophobicContact CB-CB 4.25Å; P372-L384 HydrophobicContact CG-CB 4.02Å; P372-L384 HydrophobicContact CG-CD1 3.93Å; V375-L384 HydrophobicContact CG1-CD1 4.28Å; V375-L384 HydrophobicContact CG2-CD1 4.47Å; E379-L384 HydrophobicContact CB-CD2 3.48Å; E379-L384 VanDerWaalsContact CB-CD2 3.48Å; E379-L384 HydrophobicContact CG-CD2 4.48Å; K382-L384 PolarHBondContact O-N 3.22Å; L384-S386 PolarHBondContact O-N 2.74Å; L384-A394 HydrophobicContact CB-CB 4.39Å; L384-A394 WeakPolarHBondContact CB-O 3.2Å; L384-A394 WeakPolarHBondContact CG-O 3.3Å; L384-A394 PolarHBondContact N-O 2.99Å; L384-M396 HydrophobicContact CD1-CB 4.31Å; L384-I402 HydrophobicContact CD1-CG2 4.4Å
385V97.5Very high94.1Very high14 Ų1468.2 Ų68.29%0.08537%0.367CS..  trans-76.3111.7178.3-179.30000109.8V370 N383 L387 T390 A394V370-V385 HydrophobicContact CB-CG1 4.28Å; V370-V385 HydrophobicContact CB-CG2 4Å; V370-V385 HydrophobicContact CG1-CG1 3.92Å; V370-V385 HydrophobicContact CG1-CG2 3.92Å; N383-V385 PolarHBondContact ND2-O 2.85Å; N383-V385 WeakPolarHBondContact OD1-CB 3.33Å; N383-V385 PolarHBondContact OD1-N 3.27Å; V385-L387 HydrophobicContact CG1-CB 4.33Å; V385-T390 HydrophobicContact CG1-CG2 3.87Å; V385-A394 HydrophobicContact CG2-CB 3.77Å
386S96.6Very high94.5Very high91 Ų9167.2 Ų67.264%0.63636%0.36SS*.  trans-1041.1179.364.50000114.1F324 L384F324-S386 WeakPolarHBondContact CE2-OG 3.22Å; F324-S386 VanDerWaalsContact CZ-OG 3.31Å; F324-S386 WeakPolarHBondContact CZ-OG 3.09Å; L384-S386 PolarHBondContact O-N 2.74Å
387L97.4Very high94.8Very high7 Ų765.9 Ų65.94%0.03735%0.354CS..  trans-65.7126.2178.9-66.4174.6000110.5D321 Q322 F324 V326 V370 V385 Y389 T390D321-L387 HydrophobicContact CB-CD2 4.48Å; Q322-L387 HydrophobicContact CB-CD2 4Å; F324-L387 HydrophobicContact CB-CD1 4Å; F324-L387 HydrophobicContact CD2-CD1 4.03Å; F324-L387 HydrophobicContact CD2-CD2 3.87Å; F324-L387 HydrophobicContact CD2-CG 3.71Å; F324-L387 HydrophobicContact CE2-CD2 4.32Å; F324-L387 HydrophobicContact CE2-CG 4.12Å; F324-L387 HydrophobicContact CG-CD1 4.05Å; F324-L387 HydrophobicContact CG-CG 4.17Å; V326-L387 HydrophobicContact CG2-CD1 3.92Å; V370-L387 HydrophobicContact CG1-CD1 3.97Å; V385-L387 HydrophobicContact CG1-CB 4.33Å; L387-Y389 VanDerWaalsContact C-N 3.28Å; L387-Y389 HydrophobicContact CB-CD1 4.43Å; L387-Y389 HydrophobicContact CB-CE1 4.09Å; L387-Y389 HydrophobicContact CD1-CE1 4.32Å; L387-Y389 HydrophobicContact CD2-CE1 4.09Å; L387-Y389 HydrophobicContact CG-CE1 4.41Å; L387-Y389 PolarHBondContact O-N 3.44Å; L387-T390 HydrophobicContact CB-CG2 3.92Å
388P97.3Very high95.2Very high118 Ų11861.6 Ų61.677%0.76635%0.351SS*.THydrogen-bonded Turntrans-76.1-13.6-169.729.8-36.5000114.3
389Y97.1Very high95.5Very high78 Ų7860 Ų6031%0.30635%0.347SS..THydrogen-bonded Turntrans-102-0.9-17063-101.9000114.3Y319 D321 L387Y319-Y389 PolarHBondContact OH-OH 2.98Å; D321-Y389 WeakPolarHBondContact OD2-CE1 3.47Å; D321-Y389 PolarHBondContact OD2-OH 3.26Å; L387-Y389 VanDerWaalsContact C-N 3.28Å; L387-Y389 HydrophobicContact CB-CD1 4.43Å; L387-Y389 HydrophobicContact CB-CE1 4.09Å; L387-Y389 HydrophobicContact CD1-CE1 4.32Å; L387-Y389 HydrophobicContact CD2-CE1 4.09Å; L387-Y389 HydrophobicContact CG-CE1 4.41Å; L387-Y389 PolarHBondContact O-N 3.44Å
390T98.4Very high95.7Very high18 Ų1858.2 Ų58.211%0.1135%0.349CS..  trans-125149.9-176.4-172.40000111.2V370 V385 L387 A392 E407V370-T390 HydrophobicContact CG2-CG2 4.1Å; V385-T390 HydrophobicContact CG1-CG2 3.87Å; L387-T390 HydrophobicContact CB-CG2 3.92Å; T390-A392 HydrophobicContact CG2-CB 4.44Å; T390-A392 PolarHBondContact OG1-N 3.29Å; T390-E407 WeakPolarHBondContact CA-OE2 3.27Å; T390-E407 WeakPolarHBondContact CB-OE2 3.47Å; T390-E407 PolarHBondContact OG1-OE2 3.17Å
391T98.6Very high95.9Very high97 Ų9754.4 Ų54.460%0.59533%0.331SS*.  trans-97.82.917267.10000112.7E407T391-E407 WeakPolarHBondContact OG1-CB 3.14Å; T391-E407 WeakPolarHBondContact OG1-CG 3.42Å
392A98.7Very high96.2Very high1 Ų151.7 Ų51.71%0.00830%0.303CS..  trans-64.5148.5175.600000110.1V370 T390 E405 E407V370-A392 HydrophobicContact CB-CB 4.18Å; V370-A392 HydrophobicContact CG2-CB 3.7Å; T390-A392 HydrophobicContact CG2-CB 4.44Å; T390-A392 PolarHBondContact OG1-N 3.29Å; A392-E405 WeakPolarHBondContact CA-O 3.46Å; A392-E407 HydrophobicContact CB-CB 4.17Å
393T98.7Very high96.4Very high42 Ų4248.9 Ų48.926%0.25829%0.289SS..EExtended strand (participates in β ladder)trans-132.1151.9179.774.50000111.1N383 L404 E405N383-T393 VanDerWaalsContact OD1-CA 3.3Å; N383-T393 WeakPolarHBondContact OD1-CA 3.32Å; N383-T393 WeakPolarHBondContact OD1-CB 3.26Å; T393-L404 WeakPolarHBondContact O-CA 3.29Å; T393-E405 PolarHBondContact N-O 3.07Å; T393-E405 PolarHBondContact O-N 3.03Å; T393-E405 WeakPolarHBondContact OG1-CB 3.45Å
394A98.4Very high96.5Very high0 Ų045.3 Ų45.30%027%0.269CS..EExtended strand (participates in β ladder)trans-134.3114.8172.100000107.9P372 N383 L384 V385 I402 W403 L404P372-A394 HydrophobicContact CG-CB 4.13Å; N383-A394 PolarHBondContact OD1-N 3.4Å; N383-A394 PolarHBondContact OD1-O 3.01Å; L384-A394 HydrophobicContact CB-CB 4.39Å; L384-A394 WeakPolarHBondContact CB-O 3.2Å; L384-A394 WeakPolarHBondContact CG-O 3.3Å; L384-A394 PolarHBondContact N-O 2.99Å; V385-A394 HydrophobicContact CG2-CB 3.77Å; A394-I402 HydrophobicContact CB-CG2 3.92Å; A394-W403 CarbonylContact C-O 3.14Å; A394-W403 WeakPolarHBondContact CA-O 3.2Å; A394-L404 HydrophobicContact CB-CD2 3.5Å; A394-L404 VanDerWaalsContact CB-CD2 3.5Å
395V98Very high96.6Very high39 Ų3948.5 Ų48.524%0.23628%0.284CS..EExtended strand (participates in β ladder)trans-119.5122.1-175.6-178.70000110.1H397 I402 W403V395-H397 PolarHBondContact O-CD2 2.89Å; V395-I402 WeakPolarHBondContact O-CA 3.38Å; V395-W403 PolarHBondContact N-O 3Å; V395-W403 PolarHBondContact O-N 3.34Å
396M96.3Very high96.6Very high13 Ų1348.9 Ų48.96%0.06429%0.287CS..EExtended strand (participates in β ladder)trans-79.2126.4175.4-174.5-167.4-61.300111.4V375 Q380 G381 L384 M401 I402V375-M396 HydrophobicContact CB-CE 4.47Å; V375-M396 HydrophobicContact CG1-CE 2.98Å; Q380-M396 HydrophobicContact CB-SD 4.49Å; G381-M396 PolarHBondContact N-O 2.82Å; L384-M396 HydrophobicContact CD1-CB 4.31Å; M396-M401 CarbonylContact C-O 3.58Å; M396-M401 WeakPolarHBondContact CA-O 3.45Å; M396-I402 HydrophobicContact CB-CG1 4.31Å; M396-I402 HydrophobicContact CG-CG1 4.37Å
397H94.1Very high96.7Very high78 Ų7845 Ų4536%0.36126%0.259SS..  trans-88.5167.4174.6-70.9-159.2000111.7V395 D399 G400 M401V395-H397 PolarHBondContact O-CD2 2.89Å; H397-D399 WeakPolarHBondContact CB-OD1 3.27Å; H397-D399 PolarHBondContact O-N 2.67Å; H397-G400 PolarHBondContact O-N 2.84Å; H397-M401 HydrophobicContact CB-CE 4.41Å; H397-M401 PolarHBondContact N-O 3Å; H397-M401 WeakPolarHBondContact ND1-CE 3.39Å
398A91.3Very high96.8Very high85 Ų8547.1 Ų47.170%0.70227%0.272SS*.THydrogen-bonded Turntrans-63.3-22.9-176.700000114.8Q380 G400Q380-A398 VanDerWaalsContact NE2-CA 3.34Å; A398-G400 VanDerWaalsContact C-N 3.27Å
399D90.2Very high96.9Very high119 Ų11941.8 Ų41.864%0.63624%0.237SC*.THydrogen-bonded Turntrans-863.1176.365.5-10.4000113.1H397 M401H397-D399 WeakPolarHBondContact CB-OD1 3.27Å; H397-D399 PolarHBondContact O-N 2.67Å; D399-M401 VanDerWaalsContact C-N 3.3Å; D399-M401 VanDerWaalsContact OD1-CB 3.24Å; D399-M401 WeakPolarHBondContact OD1-CB 3.18Å; D399-M401 PolarHBondContact OD1-N 3.09Å
400G90.7Very high96.9Very high35 Ų3540.2 Ų40.236%0.36123%0.232SC..SBendtrans81.42.3-177.600000114.5H397 A398H397-G400 PolarHBondContact O-N 2.84Å; A398-G400 VanDerWaalsContact C-N 3.27Å
401M94.9Very high96.9Very high24 Ų2442.3 Ų42.312%0.11825%0.247CC..  trans-69.9140.9170.3-176.3-168.970.800110.1K306 M396 H397 D399 W403K306-M401 HydrophobicContact CB-CG 4.11Å; K306-M401 HydrophobicContact CB-SD 3.79Å; K306-M401 HydrophobicContact CD-CG 4.39Å; K306-M401 HydrophobicContact CD-SD 3.68Å; K306-M401 HydrophobicContact CG-CG 4.08Å; K306-M401 HydrophobicContact CG-SD 3.91Å; M396-M401 CarbonylContact C-O 3.58Å; M396-M401 WeakPolarHBondContact CA-O 3.45Å; H397-M401 HydrophobicContact CB-CE 4.41Å; H397-M401 PolarHBondContact N-O 3Å; H397-M401 WeakPolarHBondContact ND1-CE 3.39Å; D399-M401 VanDerWaalsContact C-N 3.3Å; D399-M401 VanDerWaalsContact OD1-CB 3.24Å; D399-M401 WeakPolarHBondContact OD1-CB 3.18Å; D399-M401 PolarHBondContact OD1-N 3.09Å; M401-W403 HydrophobicContact CE-CB 4.31Å; M401-W403 HydrophobicContact CE-CE3 3.82Å; M401-W403 HydrophobicContact SD-CE3 4.37Å
402I97.8Very high96.8Very high1 Ų138.2 Ų38.21%0.00522%0.224CC..EExtended strand (participates in β ladder)trans-108.8111.8175.3-57.9162.8000107.7K304 F305 K306 V375 L384 A394 V395 M396 L404K304-I402 PolarHBondContact O-N 2.97Å; F305-I402 CarbonylContact C-O 3.52Å; F305-I402 WeakPolarHBondContact CA-O 3.29Å; F305-I402 HydrophobicContact CD1-CB 3.69Å; F305-I402 HydrophobicContact CD1-CD1 3.88Å; F305-I402 HydrophobicContact CD1-CG1 4.4Å; F305-I402 HydrophobicContact CD1-CG2 3.75Å; F305-I402 HydrophobicContact CE1-CB 4.02Å; F305-I402 HydrophobicContact CE1-CD1 3.35Å; F305-I402 HydrophobicContact CE1-CG1 4.29Å; F305-I402 HydrophobicContact CE1-CG2 3.96Å; F305-I402 HydrophobicContact CZ-CD1 3.93Å; K306-I402 PolarHBondContact N-O 3.11Å; V375-I402 HydrophobicContact CG1-CD1 3.94Å; V375-I402 HydrophobicContact CG2-CD1 4.03Å; L384-I402 HydrophobicContact CD1-CG2 4.4Å; A394-I402 HydrophobicContact CB-CG2 3.92Å; V395-I402 WeakPolarHBondContact O-CA 3.38Å; M396-I402 HydrophobicContact CB-CG1 4.31Å; M396-I402 HydrophobicContact CG-CG1 4.37Å; I402-L404 HydrophobicContact CG2-CD2 4.1Å
403W98.4Very high96.6Very high74 Ų7442.4 Ų42.428%0.2825%0.251SS..EExtended strand (participates in β ladder)trans-85.8123.9179.2-171.7-96000110.7K306 G307 A308 A394 V395 M401 E405K306-W403 HydrophobicContact CB-CE3 4.11Å; K306-W403 HydrophobicContact CB-CZ3 4.25Å; K306-W403 CarbonylContact O-C 3.3Å; K306-W403 WeakPolarHBondContact O-CA 3.25Å; G307-W403 VanDerWaalsContact C-CH2 3.42Å; A308-W403 HydrophobicContact CB-CZ2 4.44Å; A394-W403 CarbonylContact C-O 3.14Å; A394-W403 WeakPolarHBondContact CA-O 3.2Å; V395-W403 PolarHBondContact N-O 3Å; V395-W403 PolarHBondContact O-N 3.34Å; M401-W403 HydrophobicContact CE-CB 4.31Å; M401-W403 HydrophobicContact CE-CE3 3.82Å; M401-W403 HydrophobicContact SD-CE3 4.37Å; W403-E405 PolarHBondContact NE1-OE1 3.1Å
404L98.7Very high96.5Very high1 Ų142.7 Ų42.71%0.00525%0.247CC..EExtended strand (participates in β ladder)trans-101.3127.8179.6-54.6-172.8000110.7F290 F305 K306 Y369 I371 T393 A394 I402F290-L404 HydrophobicContact CB-CD1 4.37Å; F290-L404 HydrophobicContact CD2-CD1 3.61Å; F290-L404 HydrophobicContact CD2-CG 4.33Å; F290-L404 HydrophobicContact CE2-CB 4.34Å; F290-L404 HydrophobicContact CE2-CD1 3.95Å; F290-L404 HydrophobicContact CE2-CG 4.46Å; F290-L404 HydrophobicContact CG-CD1 3.93Å; F305-L404 HydrophobicContact CB-CD1 4.17Å; F305-L404 HydrophobicContact CB-CG 4.41Å; F305-L404 HydrophobicContact CD1-CD2 4.19Å; K306-L404 PolarHBondContact O-N 3.34Å; Y369-L404 HydrophobicContact CD1-CB 3.92Å; Y369-L404 HydrophobicContact CD1-CD1 4.34Å; Y369-L404 HydrophobicContact CE1-CB 4.26Å; I371-L404 HydrophobicContact CD1-CD1 4.29Å; I371-L404 HydrophobicContact CG1-CD1 3.74Å; T393-L404 WeakPolarHBondContact O-CA 3.29Å; A394-L404 HydrophobicContact CB-CD2 3.5Å; A394-L404 VanDerWaalsContact CB-CD2 3.5Å; I402-L404 HydrophobicContact CG2-CD2 4.1Å
405E98.6Very high96.5Very high83 Ų8344.1 Ų44.139%0.38825%0.254SS..EExtended strand (participates in β ladder)trans-112.1131.4166.4-67.9-68.617100109.7A392 T393 W403A392-E405 WeakPolarHBondContact CA-O 3.46Å; T393-E405 PolarHBondContact N-O 3.07Å; T393-E405 PolarHBondContact O-N 3.03Å; T393-E405 WeakPolarHBondContact OG1-CB 3.45Å; W403-E405 PolarHBondContact NE1-OE1 3.1Å
406P98.7Very high96.5Very high23 Ų2342.4 Ų42.415%0.14924%0.244CC..PPolyproline II helixtrans-78.4154.9-175.831.8-34.2000112.5R367 R368 Y369R367-P406 HydrophobicContact CB-CB 3.84Å; R367-P406 HydrophobicContact CG-CB 4.04Å; R367-P406 HydrophobicContact CG-CG 4.22Å; R368-P406 CarbonylContact O-C 3.54Å; R368-P406 VanDerWaalsContact O-CA 3.23Å; R368-P406 WeakPolarHBondContact O-CA 3.47Å; Y369-P406 HydrophobicContact CD1-CB 4.08Å; Y369-P406 HydrophobicContact CD2-CB 4.26Å; Y369-P406 HydrophobicContact CE1-CB 3.72Å; Y369-P406 HydrophobicContact CE1-CG 4.06Å; Y369-P406 HydrophobicContact CE2-CB 3.9Å; Y369-P406 HydrophobicContact CG-CB 4.34Å
407E98.8Very high96.6Very high9 Ų942 Ų424%0.04224%0.242CC..EExtended strand (participates in β ladder)trans-82.6126.4152.1167.6173.8-14900109.4R368 T390 T391 A392 L409 K456R368-E407 HydrophobicContact CB-CB 4.16Å; R368-E407 PolarHBondContact N-O 3.03Å; R368-E407 PolarHBondContact O-N 2.7Å; T390-E407 WeakPolarHBondContact CA-OE2 3.27Å; T390-E407 WeakPolarHBondContact CB-OE2 3.47Å; T390-E407 PolarHBondContact OG1-OE2 3.17Å; T391-E407 WeakPolarHBondContact OG1-CB 3.14Å; T391-E407 WeakPolarHBondContact OG1-CG 3.42Å; A392-E407 HydrophobicContact CB-CB 4.17Å; E407-L409 HydrophobicContact CG-CD2 4.02Å; E407-K456 WeakPolarHBondContact OE1-CE 3.16Å; E407-K456 IonicContact OE1-NZ 3.69Å; E407-K456 PolarHBondContact OE1-NZ 2.8Å
408V98.8Very high96.8Very high51 Ų5138.6 Ų38.631%0.30923%0.226SC..EExtended strand (participates in β ladder)trans-80.7125.2174178.80000109.8E365 K456E365-V408 VanDerWaalsContact CD-CG2 3.4Å; E365-V408 HydrophobicContact CG-CB 4.42Å; E365-V408 HydrophobicContact CG-CG1 3.54Å; E365-V408 HydrophobicContact CG-CG2 4.14Å; E365-V408 VanDerWaalsContact OE1-CG2 3.29Å; E365-V408 WeakPolarHBondContact OE1-CG2 3.23Å; V408-K456 PolarHBondContact O-NZ 3.41Å; V408-K456 VanDerWaalsContact O-NZ 3.15Å
409L98.8Very high97.2Very high6 Ų636.1 Ų36.13%0.03120%0.199CC..EExtended strand (participates in β ladder)trans-97.8-37.2178.7-57-177000112.3D328 V366 R368 E407 L451 V453D328-L409 HydrophobicContact CB-CD1 4.36Å; V366-L409 HydrophobicContact CB-CB 4.24Å; V366-L409 HydrophobicContact CG1-CB 3.91Å; V366-L409 HydrophobicContact CG1-CD1 4.05Å; V366-L409 HydrophobicContact CG1-CG 4.4Å; V366-L409 PolarHBondContact O-N 2.64Å; R368-L409 HydrophobicContact CB-CD1 4.07Å; R368-L409 HydrophobicContact CB-CD2 4.15Å; R368-L409 HydrophobicContact CB-CG 4.07Å; E407-L409 HydrophobicContact CG-CD2 4.02Å; L409-L451 HydrophobicContact CB-CD2 4.22Å; L409-V453 HydrophobicContact CD1-CB 4.03Å; L409-V453 HydrophobicContact CD1-CG1 4.17Å
410F98.7Very high97.6Very high46 Ų4631.1 Ų31.120%0.20217%0.173CC..EExtended strand (participates in β ladder)trans-149.6134.2177.8173.5-94000110.5E365 V366 Q415 F417 L451 T458E365-F410 WeakPolarHBondContact CA-O 3.48Å; E365-F410 WeakPolarHBondContact CG-O 3.34Å; V366-F410 HydrophobicContact CB-CB 3.94Å; V366-F410 HydrophobicContact CG2-CB 3.91Å; V366-F410 HydrophobicContact CG2-CD1 4.23Å; V366-F410 PolarHBondContact N-O 3.21Å; V366-F410 PolarHBondContact O-N 2.96Å; F410-Q415 WeakPolarHBondContact CE1-O 3.42Å; F410-F417 HydrophobicContact CD1-CB 3.7Å; F410-F417 HydrophobicContact CE1-CB 3.88Å; F410-F417 HydrophobicContact CG-CB 4.41Å; F410-L451 HydrophobicContact CB-CD1 4.47Å; F410-L451 HydrophobicContact CB-CD2 4.24Å; F410-T458 HydrophobicContact CD2-CG2 4.03Å; F410-T458 HydrophobicContact CE2-CG2 4.44Å
411S97.9Very high98Very high62 Ų6231.6 Ų31.643%0.43417%0.166SC..  trans-151110.8178.3-159.20000109.8E365E365-S411 WeakPolarHBondContact OE2-CB 3.11Å; E365-S411 PolarHBondContact OE2-OG 2.9Å
412G95.5Very high98.2Very high10 Ų1030.7 Ų30.710%0.10316%0.162CC..BIsolated β-bridgetrans-125.2133177.500000110.7Q363 R414 Q415Q363-G412 PolarHBondContact NE2-O 2.96Å; G412-R414 PolarHBondContact O-N 3.18Å; G412-Q415 PolarHBondContact O-N 2.77Å
413P96.4Very high98.2Very high89 Ų8930.9 Ų30.958%0.57816%0.163SC*.THydrogen-bonded Turntrans-57.2111-177-25.234000112.1Q415P413-Q415 PolarHBondContact O-N 2.8Å; P413-Q415 VanDerWaalsContact O-N 3.12Å
414R96.3Very high98.1Very high49 Ų4930.9 Ų30.919%0.18516%0.163CC..THydrogen-bonded Turntrans54.224-174.2-47.5-61.2140.5138.4-5.6114.7A358 M359 A361 G412 H442A358-R414 PolarHBondContact O-NH1 3.27Å; M359-R414 VanDerWaalsContact C-NH1 3.3Å; M359-R414 PolarHBondContact O-NH1 3.38Å; M359-R414 HydrophobicContact SD-CG 4.34Å; A361-R414 PolarHBondContact O-NH1 2.83Å; A361-R414 PolarHBondContact O-NH2 2.9Å; G412-R414 PolarHBondContact O-N 3.18Å; R414-H442 PolarHBondContact O-N 3.49Å
415Q97.3Very high97.9Very high29 Ų2937.4 Ų37.414%0.13619%0.193CC..EExtended strand (participates in β ladder)trans-112105.7172.8-56.9-53.5-30.300108.2F410 G412 P413 L440 N441 R447F410-Q415 WeakPolarHBondContact CE1-O 3.42Å; G412-Q415 PolarHBondContact O-N 2.77Å; P413-Q415 PolarHBondContact O-N 2.8Å; P413-Q415 VanDerWaalsContact O-N 3.12Å; Q415-L440 CarbonylContact C-O 3.43Å; Q415-L440 VanDerWaalsContact CA-O 3.32Å; Q415-L440 WeakPolarHBondContact CA-O 3.27Å; Q415-N441 PolarHBondContact NE2-OD1 2.97Å; Q415-N441 VanDerWaalsContact OE1-CA 3.28Å; Q415-R447 VanDerWaalsContact CD-NH2 3.33Å
416A98.5Very high97.8Very high3 Ų337.8 Ų37.83%0.02519%0.194CC..EExtended strand (participates in β ladder)trans-87.2142176.700000110.3W332 P364 E418 G439 L440W332-A416 HydrophobicContact CH2-CB 3.83Å; W332-A416 HydrophobicContact CZ2-CB 3.92Å; P364-A416 HydrophobicContact CB-CB 3.53Å; P364-A416 HydrophobicContact CG-CB 3.75Å; A416-E418 HydrophobicContact CB-CB 4.35Å; A416-E418 HydrophobicContact CB-CG 3.88Å; A416-G439 VanDerWaalsContact O-CA 3.25Å; A416-G439 WeakPolarHBondContact O-CA 3.39Å; A416-L440 HydrophobicContact CB-CB 3.89Å; A416-L440 HydrophobicContact CB-CD1 4.26Å; A416-L440 HydrophobicContact CB-CG 4.25Å; A416-L440 PolarHBondContact N-O 3.29Å; A416-L440 PolarHBondContact O-N 3.02Å
417F98.8Very high97.7Very high6 Ų639.6 Ų39.63%0.02620%0.198CC..EExtended strand (participates in β ladder)trans-96.7109.3153.5177.6-79.1000104.9I316 C330 V366 F410 P420 A435 Y436 C449 L451I316-F417 HydrophobicContact CD1-CD1 4.45Å; I316-F417 HydrophobicContact CD1-CE1 4.13Å; C330-F417 PolarHBondContact SG-O 2.91Å; V366-F417 HydrophobicContact CG2-CB 3.7Å; V366-F417 HydrophobicContact CG2-CD1 3.74Å; V366-F417 HydrophobicContact CG2-CG 3.97Å; F410-F417 HydrophobicContact CD1-CB 3.7Å; F410-F417 HydrophobicContact CE1-CB 3.88Å; F410-F417 HydrophobicContact CG-CB 4.41Å; F417-P420 HydrophobicContact CE1-CB 4.01Å; F417-A435 HydrophobicContact CE1-CB 4.26Å; F417-A435 HydrophobicContact CZ-CB 3.84Å; F417-Y436 WeakPolarHBondContact CZ-O 3.25Å; F417-C449 HydrophobicContact CD2-CB 3.63Å; F417-C449 HydrophobicContact CE2-CB 3.83Å; F417-L451 HydrophobicContact CD2-CB 4.49Å; F417-L451 HydrophobicContact CE2-CB 3.92Å; F417-L451 HydrophobicContact CZ-CB 4.26Å
418E98.6Very high97.7Very high5 Ų540.1 Ų40.12%0.02321%0.206CC..EExtended strand (participates in β ladder)trans-134.8175.7-174.3-94.2-67.2-178.100110.8H314 W332 A416 G437 L438 L440H314-E418 IonicContact CE1-OE2 3.23Å; H314-E418 IonicContact CG-OE2 2.71Å; H314-E418 IonicContact ND1-OE2 3.5Å; H314-E418 PolarHBondContact ND1-OE2 3.18Å; W332-E418 HydrophobicContact CZ2-CG 3.94Å; W332-E418 PolarHBondContact NE1-OE1 3.41Å; A416-E418 HydrophobicContact CB-CB 4.35Å; A416-E418 HydrophobicContact CB-CG 3.88Å; E418-G437 CarbonylContact O-C 3.32Å; E418-G437 WeakPolarHBondContact O-CA 3.37Å; E418-L438 PolarHBondContact N-O 3.02Å; E418-L438 PolarHBondContact O-N 2.77Å; E418-L440 HydrophobicContact CB-CD1 3.83Å; E418-L440 HydrophobicContact CB-CG 4.18Å; E418-L440 HydrophobicContact CG-CD1 4.04Å
419F98.8Very high97.7Very high34 Ų3438.1 Ų38.115%0.14920%0.196CC..EExtended strand (participates in β ladder)trans4955.6-174.1-61.3-97.8000111.5L438 L440 E470 F526 H527F419-L438 HydrophobicContact CB-CB 3.95Å; F419-L438 HydrophobicContact CD2-CB 4.05Å; F419-L438 HydrophobicContact CD2-CD2 3.73Å; F419-L438 HydrophobicContact CD2-CG 4.41Å; F419-L438 HydrophobicContact CE2-CD2 4.13Å; F419-L438 HydrophobicContact CG-CB 4.31Å; F419-L438 HydrophobicContact CG-CD2 4.21Å; F419-L440 HydrophobicContact CE2-CD1 4.45Å; F419-E470 HydrophobicContact CB-CB 3.82Å; F419-E470 HydrophobicContact CB-CG 3.88Å; F419-E470 HydrophobicContact CD1-CB 4.23Å; F419-E470 HydrophobicContact CG-CB 4.34Å; F419-F526 WeakPolarHBondContact CD1-O 3.41Å; F419-F526 HydrophobicContact CE1-CB 4.15Å; F419-F526 HydrophobicContact CE1-CD1 4.32Å; F419-F526 HydrophobicContact CZ-CD1 4.33Å; F419-H527 AromaticContact CD1-CE1 3.23Å; F419-H527 WeakPolarHBondContact CD1-CE1 3.33Å; F419-H527 AromaticContact CD1-ND1 3.82Å; F419-H527 AromaticContact CD1-NE2 3.85Å; F419-H527 AromaticContact CE1-CE1 3.57Å; F419-H527 AromaticContact CE1-NE2 3.69Å
420P98.8Very high97.6Very high14 Ų1442.6 Ų42.69%0.09122%0.215CC..EExtended strand (participates in β ladder)trans-70.2141.5-172.332.2-36.6000111.4H314 I316 F417 Y436H314-P420 HydrophobicContact CB-CG 3.5Å; I316-P420 HydrophobicContact CB-CB 4.22Å; I316-P420 HydrophobicContact CD1-CB 4.46Å; I316-P420 HydrophobicContact CG1-CB 3.71Å; I316-P420 HydrophobicContact CG1-CG 3.95Å; I316-P420 HydrophobicContact CG2-CB 4.21Å; F417-P420 HydrophobicContact CE1-CB 4.01Å; P420-Y436 CarbonylContact C-O 3.44Å; P420-Y436 VanDerWaalsContact CA-O 3.29Å; P420-Y436 WeakPolarHBondContact CA-O 3.28Å
421Q98.7Very high97.6Very high45 Ų4543 Ų4321%0.2122%0.22CC..EExtended strand (participates in β ladder)trans-134.6149.6175.7-72.4-67.8-24.600109.1Y436 E470 P471 L472Q421-Y436 PolarHBondContact N-O 3.12Å; Q421-Y436 PolarHBondContact O-N 3.21Å; Q421-E470 HydrophobicContact CG-CG 3.78Å; Q421-E470 VanDerWaalsContact NE2-CD 3.34Å; Q421-E470 PolarHBondContact NE2-OE1 3.18Å; Q421-P471 VanDerWaalsContact CB-O 3.29Å; Q421-P471 WeakPolarHBondContact CB-O 3.29Å; Q421-P471 WeakPolarHBondContact CG-O 3.31Å; Q421-L472 HydrophobicContact CG-CD2 3.96Å
422I98.8Very high97.6Very high5 Ų540.1 Ų40.13%0.02620%0.199CC..  trans-135.3177176.659.5162.3000108.8I316 N317 Y424 Y432 A435I316-I422 HydrophobicContact CG2-CG2 4.09Å; N317-I422 HydrophobicContact CB-CD1 4.11Å; I422-Y424 HydrophobicContact CD1-CD2 4.07Å; I422-Y424 HydrophobicContact CG1-CD2 4.11Å; I422-Y424 PolarHBondContact O-N 2.9Å; I422-Y432 HydrophobicContact CG2-CD2 4.05Å; I422-Y432 HydrophobicContact CG2-CE2 3.8Å; I422-A435 HydrophobicContact CG2-CB 4.19Å
423N98.2Very high97.8Very high4 Ų440.7 Ų40.72%0.02120%0.202CC..  trans-71.172.2161.7-175.5-9000110Q425 K426 Y427 F473 Q475 E482N423-Q425 PolarHBondContact O-N 2.99Å; N423-K426 PolarHBondContact O-N 2.95Å; N423-Y427 HydrophobicContact CB-CD2 3.86Å; N423-Y427 WeakPolarHBondContact O-CB 3.5Å; N423-Y427 PolarHBondContact O-N 2.9Å; N423-F473 HydrophobicContact CB-CD1 3.76Å; N423-F473 HydrophobicContact CB-CE1 3.47Å; N423-F473 VanDerWaalsContact CB-CE1 3.47Å; N423-F473 HydrophobicContact CB-CZ 4.02Å; N423-F473 WeakPolarHBondContact ND2-CE1 3.04Å; N423-Q475 VanDerWaalsContact ND2-CD 3.31Å; N423-Q475 PolarHBondContact ND2-NE2 2.9Å; N423-Q475 PolarHBondContact ND2-OE1 2.82Å; N423-Q475 VanDerWaalsContact ND2-OE1 3.13Å; N423-Q475 PolarHBondContact OD1-OE1 2.63Å; N423-E482 PolarHBondContact ND2-O 3.33Å
424Y97.3Very high97.9Very high74 Ų7438.9 Ų38.929%0.2918%0.184SC..Hα-helixtrans-65.2-37.2-164.2-173.9-89.4000112.6H183 I184 I422 K426 G428H183-Y424 AromaticContact ND1-CE2 3.76Å; H183-Y424 AromaticContact ND1-CZ 3.63Å; H183-Y424 PolarHBondContact ND1-OH 3.02Å; I184-Y424 WeakPolarHBondContact O-CE1 3.42Å; I422-Y424 HydrophobicContact CD1-CD2 4.07Å; I422-Y424 HydrophobicContact CG1-CD2 4.11Å; I422-Y424 PolarHBondContact O-N 2.9Å; Y424-K426 VanDerWaalsContact C-N 3.29Å; Y424-K426 PolarHBondContact O-N 2.78Å; Y424-G428 WeakPolarHBondContact O-CA 3.46Å; Y424-G428 PolarHBondContact O-N 2.94Å
425Q94.1Very high98Very high138 Ų13836.6 Ų36.665%0.64518%0.175SC*.Hα-helixtrans-60.8-35.9-179.5-69.7-173.6-14.800113.3Q186 N423Q186-Q425 PolarHBondContact NE2-O 2.82Å; N423-Q425 PolarHBondContact O-N 2.99Å
426K95.5Very high98.1Very high91 Ų9135.2 Ų35.240%0.39617%0.169SC..Hα-helixtrans-97.8-34.3180-72.3-167.4-175.3169.40113.3N423 Y424 Q475 G479N423-K426 PolarHBondContact O-N 2.95Å; Y424-K426 VanDerWaalsContact C-N 3.29Å; Y424-K426 PolarHBondContact O-N 2.78Å; K426-Q475 VanDerWaalsContact NZ-CD 3.29Å; K426-G479 PolarHBondContact NZ-O 2.79Å
427Y97.8Very high98.1Very high61 Ų6135.1 Ų35.124%0.23917%0.167CC..Hα-helixtrans-120.2-4-167.6-63.9-89.6000114.8N317 N423 G429 K430 N431 E482N317-Y427 PolarHBondContact ND2-O 2.78Å; N423-Y427 HydrophobicContact CB-CD2 3.86Å; N423-Y427 WeakPolarHBondContact O-CB 3.5Å; N423-Y427 PolarHBondContact O-N 2.9Å; Y427-G429 PolarHBondContact O-N 2.89Å; Y427-K430 PolarHBondContact O-N 2.84Å; Y427-K430 VanDerWaalsContact O-O 3.11Å; Y427-N431 WeakPolarHBondContact CD1-O 3.35Å; Y427-E482 HydrophobicContact CD1-CG 4.39Å; Y427-E482 HydrophobicContact CD2-CG 3.86Å; Y427-E482 HydrophobicContact CE1-CB 4.42Å; Y427-E482 HydrophobicContact CE1-CG 4.26Å; Y427-E482 HydrophobicContact CE2-CB 3.91Å; Y427-E482 HydrophobicContact CE2-CG 3.71Å; Y427-E482 HydrophobicContact CG-CG 4.2Å
428G98.1Very high98.1Very high20 Ų2035.1 Ų35.121%0.20617%0.168CC..THydrogen-bonded Turntrans-61.4127.7169.800000110.6Y424 K430Y424-G428 WeakPolarHBondContact O-CA 3.46Å; Y424-G428 PolarHBondContact O-N 2.94Å; G428-K430 VanDerWaalsContact C-N 3.26Å; G428-K430 PolarHBondContact O-N 3.3Å
429G98.1Very high98.1Very high10 Ų1034.9 Ų34.910%0.10317%0.167CC..THydrogen-bonded Turntrans81.10.4-175.900000114.9M246 N317 T318 Y427M246-G429 WeakPolarHBondContact O-CA 3.37Å; N317-G429 PolarHBondContact OD1-N 3.33Å; T318-G429 CarbonylContact O-C 3.59Å; T318-G429 WeakPolarHBondContact O-CA 3.47Å; Y427-G429 PolarHBondContact O-N 2.89Å
430K98.3Very high98.1Very high100 Ų10034.1 Ų34.144%0.43516%0.164SC..SBendtrans-130.6161.2-170.5-62.8179.9-175.6172.60112.1N317 Y427 G428 Y432N317-K430 PolarHBondContact ND2-O 2.78Å; Y427-K430 PolarHBondContact O-N 2.84Å; Y427-K430 VanDerWaalsContact O-O 3.11Å; G428-K430 VanDerWaalsContact C-N 3.26Å; G428-K430 PolarHBondContact O-N 3.3Å; K430-Y432 PolarHBondContact O-N 3.06Å
431N97.8Very high98.1Very high55 Ų5533.5 Ų33.529%0.29416%0.16SC..  trans-59.7132.8176.7-160.5-19.7000110.2Y319 Y427 R454Y319-N431 HydrophobicContact CD2-CB 3.77Å; Y319-N431 HydrophobicContact CE2-CB 3.93Å; Y319-N431 HydrophobicContact CG-CB 4.28Å; Y427-N431 WeakPolarHBondContact CD1-O 3.35Å; N431-R454 PolarHBondContact OD1-NH2 3.48Å
432Y98.7Very high98Very high1 Ų131.7 Ų31.70%0.00415%0.152CC..  trans-149.1172.9-166.282.4-64000111I316 N317 Y319 D328 I422 K430 Y434 A435 V453 R454I316-Y432 HydrophobicContact CG2-CE2 4.24Å; I316-Y432 VanDerWaalsContact CG2-OH 3.31Å; I316-Y432 WeakPolarHBondContact CG2-OH 3.46Å; N317-Y432 HydrophobicContact CB-CD1 3.98Å; N317-Y432 HydrophobicContact CB-CE1 3.55Å; N317-Y432 HydrophobicContact CB-CE2 4.19Å; N317-Y432 HydrophobicContact CB-CG 4.5Å; N317-Y432 WeakPolarHBondContact ND2-CD1 3.47Å; Y319-Y432 HydrophobicContact CD1-CD1 4.17Å; Y319-Y432 HydrophobicContact CD1-CE1 4.37Å; Y319-Y432 HydrophobicContact CE1-CD1 4.11Å; Y319-Y432 HydrophobicContact CE1-CE1 4.14Å; D328-Y432 WeakPolarHBondContact CB-OH 3.44Å; D328-Y432 VanDerWaalsContact OD2-CE1 3.25Å; D328-Y432 WeakPolarHBondContact OD2-CE1 3.37Å; D328-Y432 VanDerWaalsContact OD2-CZ 3.29Å; D328-Y432 PolarHBondContact OD2-OH 2.96Å; I422-Y432 HydrophobicContact CG2-CD2 4.05Å; I422-Y432 HydrophobicContact CG2-CE2 3.8Å; K430-Y432 PolarHBondContact O-N 3.06Å; Y432-Y434 WeakPolarHBondContact CD2-O 3.34Å; Y432-A435 HydrophobicContact CE2-CB 4.33Å; Y432-V453 HydrophobicContact CD1-CG2 4.44Å; Y432-V453 HydrophobicContact CD2-CG2 4.37Å; Y432-V453 HydrophobicContact CE1-CG2 4.01Å; Y432-V453 HydrophobicContact CE2-CG1 4.1Å; Y432-V453 HydrophobicContact CE2-CG2 3.96Å; Y432-R454 PolarHBondContact O-NE 2.96Å; Y432-R454 PolarHBondContact O-NH2 3.15Å; Y432-R454 VanDerWaalsContact O-NH2 3.08Å
433S98.6Very high98Very high22 Ų2232.7 Ų32.715%0.15416%0.156CC..  trans-131.7-27-172-42.30000113.4N452 V453 R454 E482S433-N452 CarbonylContact O-C 3.52Å; S433-N452 VanDerWaalsContact O-CA 3.23Å; S433-N452 WeakPolarHBondContact O-CA 3.36Å; S433-V453 PolarHBondContact O-N 2.77Å; S433-R454 PolarHBondContact OG-NE 2.65Å; S433-E482 WeakPolarHBondContact CA-OE2 3.39Å; S433-E482 WeakPolarHBondContact CB-OE2 3.16Å; S433-E482 PolarHBondContact N-OE1 2.97Å; S433-E482 PolarHBondContact N-OE2 3.09Å; S433-E482 PolarHBondContact OG-OE2 2.95Å
434Y98.9Very high98Very high51 Ų5132.5 Ų32.520%0.216%0.155CC..EExtended strand (participates in β ladder)trans-125.4130.8-172.8-57.4-67.3000112.6Y432 L451 N452 E482 D483Y432-Y434 WeakPolarHBondContact CD2-O 3.34Å; Y434-L451 WeakPolarHBondContact CA-O 3.29Å; Y434-N452 HydrophobicContact CD1-CB 4.14Å; Y434-N452 HydrophobicContact CE1-CB 4.01Å; Y434-E482 HydrophobicContact CD2-CB 3.96Å; Y434-E482 HydrophobicContact CD2-CG 3.96Å; Y434-E482 HydrophobicContact CE2-CB 4.34Å; Y434-E482 PolarHBondContact N-OE1 3.15Å; Y434-D483 HydrophobicContact CD2-CB 3.84Å; Y434-D483 HydrophobicContact CE2-CB 4.14Å; Y434-D483 HydrophobicContact CG-CB 4.35Å
435A98.9Very high98Very high0 Ų029.5 Ų29.50%014%0.144CC..EExtended strand (participates in β ladder)trans-118.6146.6165.300000110I316 F417 I422 Y432 K450 L451 V453I316-A435 HydrophobicContact CG2-CB 3.64Å; F417-A435 HydrophobicContact CE1-CB 4.26Å; F417-A435 HydrophobicContact CZ-CB 3.84Å; I422-A435 HydrophobicContact CG2-CB 4.19Å; Y432-A435 HydrophobicContact CE2-CB 4.33Å; A435-K450 CarbonylContact O-C 3.54Å; A435-K450 WeakPolarHBondContact O-CA 3.4Å; A435-L451 PolarHBondContact N-O 2.81Å; A435-L451 PolarHBondContact O-N 3Å; A435-V453 HydrophobicContact CB-CG1 4.29Å
436Y98.9Very high98.2Very high1 Ų122.9 Ų22.90%0.00411%0.114CC..EExtended strand (participates in β ladder)trans-114.6148.1173.3-48.3-80000108.3F417 P420 Q421 C449 K450 F473 D483 L487 A507F417-Y436 WeakPolarHBondContact CZ-O 3.25Å; P420-Y436 CarbonylContact C-O 3.44Å; P420-Y436 VanDerWaalsContact CA-O 3.29Å; P420-Y436 WeakPolarHBondContact CA-O 3.28Å; Q421-Y436 PolarHBondContact N-O 3.12Å; Q421-Y436 PolarHBondContact O-N 3.21Å; Y436-C449 CarbonylContact C-O 3.55Å; Y436-C449 VanDerWaalsContact CA-O 3.3Å; Y436-C449 WeakPolarHBondContact CA-O 3.48Å; Y436-K450 HydrophobicContact CD1-CB 3.99Å; Y436-K450 HydrophobicContact CD1-CD 4.39Å; Y436-K450 HydrophobicContact CD1-CG 3.9Å; Y436-K450 HydrophobicContact CE1-CB 4.24Å; Y436-K450 HydrophobicContact CE1-CD 3.8Å; Y436-K450 HydrophobicContact CE1-CG 3.73Å; Y436-F473 HydrophobicContact CD2-CB 4.29Å; Y436-F473 HydrophobicContact CD2-CD2 4.13Å; Y436-F473 HydrophobicContact CE2-CB 4.29Å; Y436-F473 AromaticContact CE2-CD2 3.38Å; Y436-F473 HydrophobicContact CE2-CD2 3.38Å; Y436-F473 AromaticContact CE2-CE2 3.97Å; Y436-F473 HydrophobicContact CE2-CE2 3.97Å; Y436-F473 HydrophobicContact CE2-CG 4.07Å; Y436-F473 AromaticContact CZ-CD2 3.75Å; Y436-D483 WeakPolarHBondContact OH-CA 3.14Å; Y436-D483 WeakPolarHBondContact OH-CB 3.43Å; Y436-L487 HydrophobicContact CD1-CD1 3.51Å; Y436-L487 HydrophobicContact CD1-CD2 3.74Å; Y436-L487 HydrophobicContact CD1-CG 4.17Å; Y436-L487 HydrophobicContact CD2-CD2 3.81Å; Y436-L487 HydrophobicContact CE1-CD1 4.1Å; Y436-L487 HydrophobicContact CE1-CD2 4.07Å; Y436-L487 HydrophobicContact CE1-CG 4.47Å; Y436-L487 HydrophobicContact CE2-CD2 4.17Å; Y436-L487 HydrophobicContact CG-CD1 4Å; Y436-L487 HydrophobicContact CG-CD2 3.59Å; Y436-L487 HydrophobicContact CG-CG 4.43Å; Y436-A507 HydrophobicContact CE1-CB 4.05Å; Y436-A507 WeakPolarHBondContact CE1-O 3.45Å
437G98.8Very high98.3Very high0 Ų020.1 Ų20.10%010%0.1CC..EExtended strand (participates in β ladder)trans-159.2161-177.100000112.8E418 C449E418-G437 CarbonylContact O-C 3.32Å; E418-G437 WeakPolarHBondContact O-CA 3.37Å; G437-C449 PolarHBondContact N-O 2.86Å; G437-C449 PolarHBondContact O-N 3.17Å
438L98.9Very high98.4Very high7 Ų717.2 Ų17.24%0.0379%0.089CC..EExtended strand (participates in β ladder)trans-81.5125.3169.2-175.757.1000109.5E418 F419 L440 P445 I448 P468E418-L438 PolarHBondContact N-O 3.02Å; E418-L438 PolarHBondContact O-N 2.77Å; F419-L438 HydrophobicContact CB-CB 3.95Å; F419-L438 HydrophobicContact CD2-CB 4.05Å; F419-L438 HydrophobicContact CD2-CD2 3.73Å; F419-L438 HydrophobicContact CD2-CG 4.41Å; F419-L438 HydrophobicContact CE2-CD2 4.13Å; F419-L438 HydrophobicContact CG-CB 4.31Å; F419-L438 HydrophobicContact CG-CD2 4.21Å; L438-L440 HydrophobicContact CD2-CD2 3.95Å; L438-L440 HydrophobicContact CG-CD2 3.92Å; L438-P445 HydrophobicContact CD1-CB 3.84Å; L438-P445 HydrophobicContact CD2-CB 3.79Å; L438-P445 HydrophobicContact CG-CB 3.99Å; L438-I448 HydrophobicContact CD1-CD1 4.14Å; L438-P468 HydrophobicContact CD1-CB 4.23Å; L438-P468 HydrophobicContact CD1-CG 3.78Å; L438-P468 VanDerWaalsContact CD1-O 3.31Å; L438-P468 WeakPolarHBondContact CD1-O 3.32Å
439G98.6Very high98.4Very high0 Ų016.6 Ų16.60%08%0.081CC..EExtended strand (participates in β ladder)trans-81.7123172.100000111.1A416 P445 D446 R447A416-G439 VanDerWaalsContact O-CA 3.25Å; A416-G439 WeakPolarHBondContact O-CA 3.39Å; G439-P445 WeakPolarHBondContact O-CA 3.37Å; G439-D446 PolarHBondContact O-N 2.81Å; G439-R447 PolarHBondContact N-O 2.67Å
440L98.6Very high98.5Very high17 Ų1716.1 Ų16.19%0.0898%0.077CC..EExtended strand (participates in β ladder)trans-107.2117.2175.7-51.4178.8000110.8Q415 A416 E418 F419 L438 I444 P445Q415-L440 CarbonylContact C-O 3.43Å; Q415-L440 VanDerWaalsContact CA-O 3.32Å; Q415-L440 WeakPolarHBondContact CA-O 3.27Å; A416-L440 HydrophobicContact CB-CB 3.89Å; A416-L440 HydrophobicContact CB-CD1 4.26Å; A416-L440 HydrophobicContact CB-CG 4.25Å; A416-L440 PolarHBondContact N-O 3.29Å; A416-L440 PolarHBondContact O-N 3.02Å; E418-L440 HydrophobicContact CB-CD1 3.83Å; E418-L440 HydrophobicContact CB-CG 4.18Å; E418-L440 HydrophobicContact CG-CD1 4.04Å; F419-L440 HydrophobicContact CE2-CD1 4.45Å; L438-L440 HydrophobicContact CD2-CD2 3.95Å; L438-L440 HydrophobicContact CG-CD2 3.92Å; L440-I444 CarbonylContact C-O 3.54Å; L440-I444 WeakPolarHBondContact CA-O 3.36Å; L440-P445 HydrophobicContact CD2-CB 3.85Å
441N97.9Very high98.5Very high1 Ų111.4 Ų11.41%0.0056%0.056CC..EExtended strand (participates in β ladder)trans-97.7101.6175.7-175.10.9000109.6F5 W351 Q415 F443 I444 D446F5-N441 PolarHBondContact O-ND2 2.97Å; W351-N441 HydrophobicContact CH2-CB 4.46Å; Q415-N441 PolarHBondContact NE2-OD1 2.97Å; Q415-N441 VanDerWaalsContact OE1-CA 3.28Å; N441-F443 PolarHBondContact O-N 3.18Å; N441-I444 PolarHBondContact N-O 2.76Å; N441-I444 WeakPolarHBondContact O-CB 3.43Å; N441-I444 PolarHBondContact O-N 3.27Å; N441-D446 HydrophobicContact CB-CB 4.23Å; N441-D446 VanDerWaalsContact CB-CG 3.42Å; N441-D446 WeakPolarHBondContact CB-OD2 3.39Å; N441-D446 PolarHBondContact ND2-OD2 3.23Å
442H97.8Very high98.5Very high8 Ų89.4 Ų9.44%0.0375%0.046CC..THydrogen-bonded Turntrans51.945.2-172.7-54.478.4000111.7W351 V354 A358 R414 I444W351-H442 HydrophobicContact CH2-CB 4.24Å; W351-H442 AromaticContact CH2-ND1 3.83Å; W351-H442 HydrophobicContact CZ3-CB 4.39Å; V354-H442 HydrophobicContact CG1-CB 4.26Å; V354-H442 WeakPolarHBondContact CG1-O 3.43Å; A358-H442 HydrophobicContact CB-CB 3.65Å; R414-H442 PolarHBondContact O-N 3.49Å; H442-I444 VanDerWaalsContact C-N 3.25Å; H442-I444 PolarHBondContact O-N 2.84Å
443F98Very high98.5Very high25 Ų259.4 Ų9.411%0.115%0.046CC..THydrogen-bonded Turntrans74.1-11.2-174-51.2-70.9000116.9W332 V338 Y341 L342 L347 A358 A361 N441W332-F443 AromaticContact CH2-CD1 3.98Å; W332-F443 HydrophobicContact CH2-CD1 3.98Å; W332-F443 AromaticContact CH2-CE1 3.53Å; W332-F443 HydrophobicContact CH2-CE1 3.53Å; W332-F443 HydrophobicContact CH2-CZ 4.48Å; W332-F443 HydrophobicContact CZ2-CE1 4.39Å; W332-F443 HydrophobicContact CZ3-CD1 4.46Å; W332-F443 AromaticContact CZ3-CE1 3.62Å; W332-F443 HydrophobicContact CZ3-CE1 3.62Å; W332-F443 HydrophobicContact CZ3-CZ 4.16Å; V338-F443 HydrophobicContact CG1-CE1 3.63Å; V338-F443 HydrophobicContact CG1-CZ 4.15Å; Y341-F443 HydrophobicContact CD1-CE2 4.23Å; Y341-F443 HydrophobicContact CD2-CZ 4.38Å; Y341-F443 AromaticContact CG-CE2 3.87Å; Y341-F443 HydrophobicContact CG-CE2 3.87Å; Y341-F443 AromaticContact CG-CZ 3.98Å; Y341-F443 HydrophobicContact CG-CZ 3.98Å; L342-F443 HydrophobicContact CD2-CB 4.16Å; L342-F443 HydrophobicContact CD2-CD1 3.89Å; L342-F443 HydrophobicContact CD2-CG 4.06Å; L347-F443 HydrophobicContact CD2-CB 4.1Å; A358-F443 HydrophobicContact CB-CD2 3.93Å; A358-F443 HydrophobicContact CB-CE2 3.8Å; A361-F443 HydrophobicContact CB-CE2 3.82Å; A361-F443 HydrophobicContact CB-CZ 3.6Å; N441-F443 PolarHBondContact O-N 3.18Å
444I98.1Very high98.5Very high0 Ų013.8 Ų13.80%06%0.059CC..EExtended strand (participates in β ladder)trans-81.9124.2176-55.6-54.3000109.6Y12 W351 V354 L440 N441 H442 D446 Y467Y12-I444 HydrophobicContact CD1-CG1 4.43Å; Y12-I444 HydrophobicContact CD1-CG2 4.07Å; Y12-I444 HydrophobicContact CD2-CD1 3.75Å; Y12-I444 HydrophobicContact CD2-CG1 4.4Å; Y12-I444 HydrophobicContact CE2-CD1 4.08Å; Y12-I444 HydrophobicContact CG-CD1 4.07Å; Y12-I444 HydrophobicContact CG-CG1 4.33Å; Y12-I444 HydrophobicContact CG-CG2 3.92Å; W351-I444 HydrophobicContact CE3-CG1 4.46Å; W351-I444 HydrophobicContact CZ3-CB 4.37Å; W351-I444 HydrophobicContact CZ3-CG1 3.88Å; V354-I444 HydrophobicContact CG1-CD1 4.26Å; V354-I444 HydrophobicContact CG1-CG1 3.94Å; L440-I444 CarbonylContact C-O 3.54Å; L440-I444 WeakPolarHBondContact CA-O 3.36Å; N441-I444 PolarHBondContact N-O 2.76Å; N441-I444 WeakPolarHBondContact O-CB 3.43Å; N441-I444 PolarHBondContact O-N 3.27Å; H442-I444 VanDerWaalsContact C-N 3.25Å; H442-I444 PolarHBondContact O-N 2.84Å; I444-D446 PolarHBondContact O-N 2.81Å; I444-Y467 HydrophobicContact CG2-CD1 3.97Å; I444-Y467 HydrophobicContact CG2-CE1 4.07Å
445P98.2Very high98.5Very high11 Ų1115.4 Ų15.47%0.0717%0.074CC..EExtended strand (participates in β ladder)trans-71116.2177.628.4-33.2000110.6I15 L438 G439 L440 Y467 P468I15-P445 HydrophobicContact CD1-CG 3.82Å; L438-P445 HydrophobicContact CD1-CB 3.84Å; L438-P445 HydrophobicContact CD2-CB 3.79Å; L438-P445 HydrophobicContact CG-CB 3.99Å; G439-P445 WeakPolarHBondContact O-CA 3.37Å; L440-P445 HydrophobicContact CD2-CB 3.85Å; P445-Y467 WeakPolarHBondContact O-CA 3.37Å; P445-Y467 WeakPolarHBondContact O-CD1 3.47Å; P445-P468 WeakPolarHBondContact CB-O 3.34Å
446D97.6Very high98.5Very high0 Ų019.3 Ų19.30%09%0.091CC..EExtended strand (participates in β ladder)trans-130.4-6.5-170.279.2-23.8000115.4H7 G439 N441 I444 Q462H7-D446 VanDerWaalsContact NE2-CB 3.33Å; H7-D446 WeakPolarHBondContact NE2-CB 3.47Å; H7-D446 IonicContact NE2-OD2 2.69Å; G439-D446 PolarHBondContact O-N 2.81Å; N441-D446 HydrophobicContact CB-CB 4.23Å; N441-D446 VanDerWaalsContact CB-CG 3.42Å; N441-D446 WeakPolarHBondContact CB-OD2 3.39Å; N441-D446 PolarHBondContact ND2-OD2 3.23Å; I444-D446 PolarHBondContact O-N 2.81Å; D446-Q462 WeakPolarHBondContact O-CG 3.44Å; D446-Q462 PolarHBondContact O-NE2 2.78Å; D446-Q462 PolarHBondContact OD2-NE2 3.27Å
447R98.6Very high98.5Very high32 Ų3224.1 Ų24.112%0.12111%0.114CC..EExtended strand (participates in β ladder)trans-159.9161.1-17768.3-172.9114.2-110.5-10.1112.8Q415 G439 V460 W461 Q462Q415-R447 VanDerWaalsContact CD-NH2 3.33Å; G439-R447 PolarHBondContact N-O 2.67Å; R447-V460 HydrophobicContact CB-CG1 3.89Å; R447-V460 HydrophobicContact CG-CG1 4.21Å; R447-W461 WeakPolarHBondContact CA-O 3.49Å; R447-W461 WeakPolarHBondContact CB-O 3.38Å; R447-Q462 HydrophobicContact CB-CB 3.92Å; R447-Q462 HydrophobicContact CB-CG 4.27Å
448I98.9Very high98.4Very high0 Ų027.1 Ų27.10%013%0.132CC..EExtended strand (participates in β ladder)trans-102.9134.9165.3-62.1-55.2000108.9L438 V460 W461 P468 S469 P471 L487 T489 L505 L510L438-I448 HydrophobicContact CD1-CD1 4.14Å; I448-V460 WeakPolarHBondContact O-CA 3.38Å; I448-W461 HydrophobicContact CB-CB 4.38Å; I448-W461 HydrophobicContact CB-CE3 4.36Å; I448-W461 HydrophobicContact CG1-CE3 4.05Å; I448-W461 PolarHBondContact N-O 3.4Å; I448-W461 PolarHBondContact O-N 3.11Å; I448-P468 HydrophobicContact CD1-CB 3.7Å; I448-P468 HydrophobicContact CD1-CG 3.97Å; I448-P468 HydrophobicContact CG1-CB 4.01Å; I448-P468 HydrophobicContact CG1-CG 4.22Å; I448-S469 WeakPolarHBondContact CD1-O 3.03Å; I448-P471 HydrophobicContact CD1-CB 3.98Å; I448-P471 HydrophobicContact CD1-CG 4.07Å; I448-P471 HydrophobicContact CG2-CB 3.94Å; I448-P471 HydrophobicContact CG2-CG 4.07Å; I448-L487 HydrophobicContact CG2-CD1 4.15Å; I448-T489 HydrophobicContact CD1-CG2 4.32Å; I448-T489 HydrophobicContact CG1-CG2 4.13Å; I448-L505 HydrophobicContact CB-CD1 4.24Å; I448-L505 HydrophobicContact CG1-CD1 4.41Å; I448-L505 HydrophobicContact CG2-CD1 4.15Å; I448-L510 HydrophobicContact CG2-CD1 4.45Å; I448-L510 HydrophobicContact CG2-CD2 4.39Å
449C98.8Very high98.4Very high7 Ų729.7 Ų29.75%0.04714%0.141CC..EExtended strand (participates in β ladder)trans-117.2143.1-179.9-64.30000110.6F417 Y436 G437 W459F417-C449 HydrophobicContact CD2-CB 3.63Å; F417-C449 HydrophobicContact CE2-CB 3.83Å; Y436-C449 CarbonylContact C-O 3.55Å; Y436-C449 VanDerWaalsContact CA-O 3.3Å; Y436-C449 WeakPolarHBondContact CA-O 3.48Å; G437-C449 PolarHBondContact N-O 2.86Å; G437-C449 PolarHBondContact O-N 3.17Å; C449-W459 WeakPolarHBondContact CA-O 3.41Å
450K98.9Very high98.4Very high1 Ų133.3 Ų33.30%0.00416%0.163CC..EExtended strand (participates in β ladder)trans-114.7138.8160.7177.9-176.6-178.1172.90107.8A435 Y436 T458 W459 D483 A507 K508 L510A435-K450 CarbonylContact O-C 3.54Å; A435-K450 WeakPolarHBondContact O-CA 3.4Å; Y436-K450 HydrophobicContact CD1-CB 3.99Å; Y436-K450 HydrophobicContact CD1-CD 4.39Å; Y436-K450 HydrophobicContact CD1-CG 3.9Å; Y436-K450 HydrophobicContact CE1-CB 4.24Å; Y436-K450 HydrophobicContact CE1-CD 3.8Å; Y436-K450 HydrophobicContact CE1-CG 3.73Å; K450-T458 CarbonylContact O-C 3.53Å; K450-T458 WeakPolarHBondContact O-CA 3.39Å; K450-T458 WeakPolarHBondContact O-CB 3.4Å; K450-W459 HydrophobicContact CB-CB 4.19Å; K450-W459 HydrophobicContact CB-CE3 4.08Å; K450-W459 HydrophobicContact CD-CD2 4.23Å; K450-W459 HydrophobicContact CD-CE3 3.76Å; K450-W459 HydrophobicContact CD-CZ3 4.29Å; K450-W459 HydrophobicContact CG-CE3 3.84Å; K450-W459 HydrophobicContact CG-CZ3 4.37Å; K450-W459 PolarHBondContact N-O 3.06Å; K450-W459 PolarHBondContact O-N 3.45Å; K450-D483 IonicContact NZ-OD2 2.65Å; K450-D483 PolarHBondContact NZ-OD2 2.88Å; K450-A507 WeakPolarHBondContact CD-O 3.08Å; K450-A507 WeakPolarHBondContact CE-O 3.23Å; K450-A507 PolarHBondContact NZ-O 3.08Å; K450-K508 PolarHBondContact NZ-O 2.94Å; K450-L510 HydrophobicContact CB-CD1 3.95Å; K450-L510 HydrophobicContact CB-CD2 4.21Å; K450-L510 HydrophobicContact CB-CG 4.14Å
451L98.9Very high98.4Very high0 Ų033.5 Ų33.50%016%0.162CC..EExtended strand (participates in β ladder)trans-126123.2178.5172.963.4000109.1V366 L409 F410 F417 Y434 A435 V453 T458V366-L451 HydrophobicContact CG1-CD2 4.17Å; L409-L451 HydrophobicContact CB-CD2 4.22Å; F410-L451 HydrophobicContact CB-CD1 4.47Å; F410-L451 HydrophobicContact CB-CD2 4.24Å; F417-L451 HydrophobicContact CD2-CB 4.49Å; F417-L451 HydrophobicContact CE2-CB 3.92Å; F417-L451 HydrophobicContact CZ-CB 4.26Å; Y434-L451 WeakPolarHBondContact CA-O 3.29Å; A435-L451 PolarHBondContact N-O 2.81Å; A435-L451 PolarHBondContact O-N 3Å; L451-V453 HydrophobicContact CD2-CG1 4.09Å; L451-V453 HydrophobicContact CG-CG1 4.08Å; L451-V453 PolarHBondContact O-N 2.9Å; L451-T458 HydrophobicContact CD1-CG2 3.73Å
452N98.8Very high98.4Very high14 Ų1435.9 Ų35.98%0.07517%0.174CC..EExtended strand (participates in β ladder)trans-81109.6162.7-175.9-38.3000108.7S433 Y434 R454 T455 K456 E457 W459S433-N452 CarbonylContact O-C 3.52Å; S433-N452 VanDerWaalsContact O-CA 3.23Å; S433-N452 WeakPolarHBondContact O-CA 3.36Å; Y434-N452 HydrophobicContact CD1-CB 4.14Å; Y434-N452 HydrophobicContact CE1-CB 4.01Å; N452-R454 PolarHBondContact O-N 2.81Å; N452-R454 WeakPolarHBondContact OD1-CA 3.24Å; N452-R454 WeakPolarHBondContact OD1-CB 3.48Å; N452-R454 PolarHBondContact OD1-N 2.74Å; N452-T455 VanDerWaalsContact CB-OG1 3.3Å; N452-T455 WeakPolarHBondContact CB-OG1 3.19Å; N452-T455 PolarHBondContact ND2-OG1 2.88Å; N452-T455 PolarHBondContact OD1-N 2.81Å; N452-T455 PolarHBondContact OD1-OG1 3.33Å; N452-K456 WeakPolarHBondContact O-CA 3.46Å; N452-K456 PolarHBondContact O-N 3.21Å; N452-E457 HydrophobicContact CB-CB 4.34Å; N452-E457 PolarHBondContact N-O 3.17Å; N452-W459 HydrophobicContact CB-CH2 4.31Å; N452-W459 HydrophobicContact CB-CZ3 4.02Å
453V98.8Very high98.3Very high1 Ų138 Ų381%0.00618%0.183CC..THydrogen-bonded Turntrans-76.1-2.7-174.3-57.80000113.9R368 L409 Y432 S433 A435 L451R368-V453 PolarHBondContact NH1-O 3.3Å; R368-V453 VanDerWaalsContact NH2-CG2 3.3Å; R368-V453 PolarHBondContact NH2-O 3.23Å; L409-V453 HydrophobicContact CD1-CB 4.03Å; L409-V453 HydrophobicContact CD1-CG1 4.17Å; Y432-V453 HydrophobicContact CD1-CG2 4.44Å; Y432-V453 HydrophobicContact CD2-CG2 4.37Å; Y432-V453 HydrophobicContact CE1-CG2 4.01Å; Y432-V453 HydrophobicContact CE2-CG1 4.1Å; Y432-V453 HydrophobicContact CE2-CG2 3.96Å; S433-V453 PolarHBondContact O-N 2.77Å; A435-V453 HydrophobicContact CB-CG1 4.29Å; L451-V453 HydrophobicContact CD2-CG1 4.09Å; L451-V453 HydrophobicContact CG-CG1 4.08Å; L451-V453 PolarHBondContact O-N 2.9Å
454R98.1Very high98.1Very high114 Ų11441.4 Ų41.443%0.4321%0.208SC..THydrogen-bonded Turntrans-97.5-46173.8-56.2-178.7-176.5-80.7-3.5111.3N431 Y432 S433 N452N431-R454 PolarHBondContact OD1-NH2 3.48Å; Y432-R454 PolarHBondContact O-NE 2.96Å; Y432-R454 PolarHBondContact O-NH2 3.15Å; Y432-R454 VanDerWaalsContact O-NH2 3.08Å; S433-R454 PolarHBondContact OG-NE 2.65Å; N452-R454 PolarHBondContact O-N 2.81Å; N452-R454 WeakPolarHBondContact OD1-CA 3.24Å; N452-R454 WeakPolarHBondContact OD1-CB 3.48Å; N452-R454 PolarHBondContact OD1-N 2.74Å
455T98.4Very high97.9Very high85 Ų8543.6 Ų43.652%0.52122%0.218SC..THydrogen-bonded Turntrans-96.6-14.8-175.565.90000113.5N452 E457N452-T455 VanDerWaalsContact CB-OG1 3.3Å; N452-T455 WeakPolarHBondContact CB-OG1 3.19Å; N452-T455 PolarHBondContact ND2-OG1 2.88Å; N452-T455 PolarHBondContact OD1-N 2.81Å; N452-T455 PolarHBondContact OD1-OG1 3.33Å; T455-E457 PolarHBondContact O-N 3.19Å; T455-E457 WeakPolarHBondContact OG1-CB 3.14Å; T455-E457 PolarHBondContact OG1-N 3.03Å
456K98.6Very high97.8Very high82 Ų8243.2 Ų43.236%0.35722%0.216SC..  trans65.610.7-172.9-48.1175.3-169.5-170.70113.7E407 V408 N452E407-K456 WeakPolarHBondContact OE1-CE 3.16Å; E407-K456 IonicContact OE1-NZ 3.69Å; E407-K456 PolarHBondContact OE1-NZ 2.8Å; V408-K456 PolarHBondContact O-NZ 3.41Å; V408-K456 VanDerWaalsContact O-NZ 3.15Å; N452-K456 WeakPolarHBondContact O-CA 3.46Å; N452-K456 PolarHBondContact O-N 3.21Å
457E98.6Very high97.9Very high102 Ų10243.4 Ų43.448%0.47722%0.217SC..  trans-66.2141.6173-172.2177-170.100110.4N452 T455 W459N452-E457 HydrophobicContact CB-CB 4.34Å; N452-E457 PolarHBondContact N-O 3.17Å; T455-E457 PolarHBondContact O-N 3.19Å; T455-E457 WeakPolarHBondContact OG1-CB 3.14Å; T455-E457 PolarHBondContact OG1-N 3.03Å; E457-W459 HydrophobicContact CB-CH2 3.86Å; E457-W459 HydrophobicContact CB-CZ3 4.09Å; E457-W459 HydrophobicContact CG-CH2 3.49Å; E457-W459 VanDerWaalsContact CG-CH2 3.49Å; E457-W459 HydrophobicContact CG-CZ2 3.75Å; E457-W459 HydrophobicContact CG-CZ3 3.92Å; E457-W459 VanDerWaalsContact OE1-CZ2 3.32Å; E457-W459 WeakPolarHBondContact OE1-CZ2 3.13Å; E457-W459 VanDerWaalsContact OE2-CH2 3.31Å; E457-W459 WeakPolarHBondContact OE2-CH2 3.46Å
458T98.5Very high97.9Very high62 Ų6242.1 Ų42.138%0.3821%0.213SC..EExtended strand (participates in β ladder)trans-128.1148.1179.161.60000112.5F410 K450 L451F410-T458 HydrophobicContact CD2-CG2 4.03Å; F410-T458 HydrophobicContact CE2-CG2 4.44Å; K450-T458 CarbonylContact O-C 3.53Å; K450-T458 WeakPolarHBondContact O-CA 3.39Å; K450-T458 WeakPolarHBondContact O-CB 3.4Å; L451-T458 HydrophobicContact CD1-CG2 3.73Å
459W98.7Very high97.9Very high62 Ų6242.4 Ų42.424%0.23522%0.215CC..EExtended strand (participates in β ladder)trans-119.7149.1168.6-59.5-104.6000108.4C449 K450 N452 E457 L510C449-W459 WeakPolarHBondContact CA-O 3.41Å; K450-W459 HydrophobicContact CB-CB 4.19Å; K450-W459 HydrophobicContact CB-CE3 4.08Å; K450-W459 HydrophobicContact CD-CD2 4.23Å; K450-W459 HydrophobicContact CD-CE3 3.76Å; K450-W459 HydrophobicContact CD-CZ3 4.29Å; K450-W459 HydrophobicContact CG-CE3 3.84Å; K450-W459 HydrophobicContact CG-CZ3 4.37Å; K450-W459 PolarHBondContact N-O 3.06Å; K450-W459 PolarHBondContact O-N 3.45Å; N452-W459 HydrophobicContact CB-CH2 4.31Å; N452-W459 HydrophobicContact CB-CZ3 4.02Å; E457-W459 HydrophobicContact CB-CH2 3.86Å; E457-W459 HydrophobicContact CB-CZ3 4.09Å; E457-W459 HydrophobicContact CG-CH2 3.49Å; E457-W459 VanDerWaalsContact CG-CH2 3.49Å; E457-W459 HydrophobicContact CG-CZ2 3.75Å; E457-W459 HydrophobicContact CG-CZ3 3.92Å; E457-W459 VanDerWaalsContact OE1-CZ2 3.32Å; E457-W459 WeakPolarHBondContact OE1-CZ2 3.13Å; E457-W459 VanDerWaalsContact OE2-CH2 3.31Å; E457-W459 WeakPolarHBondContact OE2-CH2 3.46Å; W459-L510 HydrophobicContact CB-CD1 3.79Å; W459-L510 HydrophobicContact CB-CG 4.05Å; W459-L510 WeakPolarHBondContact O-CD1 3.45Å
460V98.5Very high97.9Very high75 Ų7542.2 Ų42.246%0.45521%0.213SC..EExtended strand (participates in β ladder)trans-135.1129.3-177.9178.80000109.8R447 I448 Q462R447-V460 HydrophobicContact CB-CG1 3.89Å; R447-V460 HydrophobicContact CG-CG1 4.21Å; I448-V460 WeakPolarHBondContact O-CA 3.38Å; V460-Q462 HydrophobicContact CG1-CB 4.14Å
461W98.6Very high97.9Very high21 Ų2142.1 Ų42.18%0.0821%0.213CC..EExtended strand (participates in β ladder)trans-102.8131159.5174.894.6000108.8R447 I448 E463 P468 V491 L503 L505 L510R447-W461 WeakPolarHBondContact CA-O 3.49Å; R447-W461 WeakPolarHBondContact CB-O 3.38Å; I448-W461 HydrophobicContact CB-CB 4.38Å; I448-W461 HydrophobicContact CB-CE3 4.36Å; I448-W461 HydrophobicContact CG1-CE3 4.05Å; I448-W461 PolarHBondContact N-O 3.4Å; I448-W461 PolarHBondContact O-N 3.11Å; W461-E463 HydrophobicContact CH2-CB 4.36Å; W461-E463 HydrophobicContact CH2-CG 4.29Å; W461-E463 HydrophobicContact CZ2-CB 4.22Å; W461-E463 HydrophobicContact CZ2-CG 3.66Å; W461-P468 HydrophobicContact CZ3-CB 4.25Å; W461-P468 HydrophobicContact CZ3-CG 4.27Å; W461-V491 HydrophobicContact CH2-CG1 4.27Å; W461-V491 HydrophobicContact CH2-CG2 4.03Å; W461-V491 HydrophobicContact CZ3-CG2 4.32Å; W461-L503 HydrophobicContact CD2-CD2 3.77Å; W461-L503 VanDerWaalsContact CE2-CD2 3.47Å; W461-L503 HydrophobicContact CE3-CD2 3.88Å; W461-L503 HydrophobicContact CH2-CD2 3.5Å; W461-L503 HydrophobicContact CZ2-CD1 4.37Å; W461-L503 HydrophobicContact CZ2-CD2 3.34Å; W461-L503 HydrophobicContact CZ2-CG 4.49Å; W461-L503 HydrophobicContact CZ3-CD2 3.76Å; W461-L505 HydrophobicContact CB-CD1 3.78Å; W461-L505 HydrophobicContact CD2-CD1 4.26Å; W461-L505 HydrophobicContact CD2-CD2 4.5Å; W461-L505 HydrophobicContact CG-CD1 3.84Å; W461-L505 HydrophobicContact CG-CD2 4.04Å; W461-L510 HydrophobicContact CB-CB 4.16Å
462Q97.8Very high97.8Very high52 Ų5242.5 Ų42.524%0.24322%0.215CC..  trans-155.6135.8180177.815950.300110.4F5 D446 R447 V460F5-Q462 HydrophobicContact CD1-CG 4.47Å; F5-Q462 VanDerWaalsContact CD1-NE2 3.31Å; F5-Q462 HydrophobicContact CD2-CG 4.21Å; F5-Q462 HydrophobicContact CE1-CG 4.12Å; F5-Q462 HydrophobicContact CE2-CG 3.84Å; F5-Q462 HydrophobicContact CG-CG 4.5Å; F5-Q462 HydrophobicContact CZ-CG 3.77Å; D446-Q462 WeakPolarHBondContact O-CG 3.44Å; D446-Q462 PolarHBondContact O-NE2 2.78Å; D446-Q462 PolarHBondContact OD2-NE2 3.27Å; R447-Q462 HydrophobicContact CB-CB 3.92Å; R447-Q462 HydrophobicContact CB-CG 4.27Å; V460-Q462 HydrophobicContact CG1-CB 4.14Å
463E95.7Very high97.8Very high51 Ų5143 Ų4324%0.23822%0.216CC..  trans-125.4147.8171.5-73.5-172.7171.800110.3W461 Y501 R515W461-E463 HydrophobicContact CH2-CB 4.36Å; W461-E463 HydrophobicContact CH2-CG 4.29Å; W461-E463 HydrophobicContact CZ2-CB 4.22Å; W461-E463 HydrophobicContact CZ2-CG 3.66Å; E463-Y501 PolarHBondContact OE2-OH 2.81Å; E463-Y501 VanDerWaalsContact OE2-OH 3.09Å; E463-R515 IonicContact OE1-CZ 2.83Å; E463-R515 IonicContact OE1-NH1 2.76Å; E463-R515 IonicContact OE1-NH2 3.38Å; E463-R515 PolarHBondContact OE1-NH2 2.8Å; E463-R515 IonicContact OE2-CZ 3.81Å; E463-R515 IonicContact OE2-NH1 3.15Å; E463-R515 PolarHBondContact OE2-NH1 3.05Å; E463-R515 IonicContact OE2-NH2 2.74Å; E463-R515 PolarHBondContact OE2-NH2 3.49Å
464P94.1Very high97.8Very high98 Ų9843.3 Ų43.364%0.63622%0.218SC*.THydrogen-bonded Turntrans-56.3141.8171.9-24.735000112.4F5 S466F5-P464 HydrophobicContact CZ-CB 4.33Å; F5-P464 HydrophobicContact CZ-CG 4.19Å; P464-S466 PolarHBondContact O-N 3.4Å; P464-S466 PolarHBondContact O-OG 2.96Å; P464-S466 VanDerWaalsContact O-OG 3.12Å
465E93.2Very high97.7Very high45 Ų4538.9 Ų38.921%0.2120%0.202CC..THydrogen-bonded Turntrans5133.2175.4-55.7-60.4116.800114.1H7 A9 S11 Y467H7-E465 IonicContact ND1-OE1 3.95Å; A9-E465 WeakPolarHBondContact CB-OE2 3.4Å; S11-E465 VanDerWaalsContact CB-OE2 3.25Å; S11-E465 WeakPolarHBondContact CB-OE2 3.49Å; S11-E465 PolarHBondContact OG-OE2 2.82Å; E465-Y467 PolarHBondContact OE2-OH 3.33Å
466S96.7Very high97.6Very high3 Ų336.9 Ų36.92%0.02119%0.19CC..  trans-125.7124.8-179.3-63.70000109.8P464 P468 A492P464-S466 PolarHBondContact O-N 3.4Å; P464-S466 PolarHBondContact O-OG 2.96Å; P464-S466 VanDerWaalsContact O-OG 3.12Å; S466-P468 WeakPolarHBondContact O-CD 3.34Å; S466-A492 WeakPolarHBondContact CA-O 3.11Å
467Y98.3Very high97.3Very high5 Ų537 Ų372%0.0220%0.199CC..EExtended strand (participates in β ladder)trans-120.294.9-171.3-49.1-74.2000109.4H7 S11 Y12 I15 I444 P445 E465 A492 P494H7-Y467 AromaticContact CE1-CE1 3.85Å; H7-Y467 AromaticContact ND1-CE1 3.66Å; S11-Y467 VanDerWaalsContact OG-CE2 3.23Å; S11-Y467 WeakPolarHBondContact OG-CE2 3.01Å; S11-Y467 PolarHBondContact OG-OH 3.03Å; Y12-Y467 VanDerWaalsContact CA-CZ 3.5Å; Y12-Y467 HydrophobicContact CD1-CE1 4.3Å; Y12-Y467 HydrophobicContact CG-CE1 4.43Å; Y12-Y467 VanDerWaalsContact N-CE2 3.29Å; Y12-Y467 PolarHBondContact N-OH 3.15Å; I15-Y467 HydrophobicContact CG2-CD2 4.34Å; I15-Y467 HydrophobicContact CG2-CG 4.44Å; I444-Y467 HydrophobicContact CG2-CD1 3.97Å; I444-Y467 HydrophobicContact CG2-CE1 4.07Å; P445-Y467 WeakPolarHBondContact O-CA 3.37Å; P445-Y467 WeakPolarHBondContact O-CD1 3.47Å; E465-Y467 PolarHBondContact OE2-OH 3.33Å; Y467-A492 WeakPolarHBondContact CD2-O 3.22Å; Y467-A492 PolarHBondContact N-O 3.49Å; Y467-A492 PolarHBondContact O-N 3.07Å; Y467-P494 HydrophobicContact CD2-CG 4.34Å; Y467-P494 HydrophobicContact CE2-CG 3.94Å
468P98.6Very high96.9Very high5 Ų539.3 Ų39.33%0.03222%0.215CC..EExtended strand (participates in β ladder)trans-75.4162-176.129-32.6000112.8L438 P445 I448 W461 S466 I490 V491L438-P468 HydrophobicContact CD1-CB 4.23Å; L438-P468 HydrophobicContact CD1-CG 3.78Å; L438-P468 VanDerWaalsContact CD1-O 3.31Å; L438-P468 WeakPolarHBondContact CD1-O 3.32Å; P445-P468 WeakPolarHBondContact CB-O 3.34Å; I448-P468 HydrophobicContact CD1-CB 3.7Å; I448-P468 HydrophobicContact CD1-CG 3.97Å; I448-P468 HydrophobicContact CG1-CB 4.01Å; I448-P468 HydrophobicContact CG1-CG 4.22Å; W461-P468 HydrophobicContact CZ3-CB 4.25Å; W461-P468 HydrophobicContact CZ3-CG 4.27Å; S466-P468 WeakPolarHBondContact O-CD 3.34Å; P468-I490 CarbonylContact C-O 3.45Å; P468-I490 WeakPolarHBondContact CA-O 3.49Å; P468-V491 HydrophobicContact CB-CG2 4.14Å
469S98.8Very high96.5Very high6 Ų636.7 Ų36.74%0.04220%0.2CC..  trans-95.2179.2166.475.90000111.1R44 I448 T489 I490 T525R44-S469 PolarHBondContact NE-OG 3.13Å; I448-S469 WeakPolarHBondContact CD1-O 3.03Å; S469-T489 PolarHBondContact N-OG1 3.2Å; S469-T489 VanDerWaalsContact N-OG1 3.14Å; S469-T489 PolarHBondContact O-OG1 2.77Å; S469-T489 PolarHBondContact OG-OG1 3.34Å; S469-I490 PolarHBondContact N-O 2.73Å; S469-I490 PolarHBondContact OG-N 3.17Å; S469-I490 PolarHBondContact OG-O 3.18Å; S469-T525 WeakPolarHBondContact CB-OG1 3.41Å
470E98.8Very high96.2Very high2 Ų239.4 Ų39.41%0.00922%0.223CC..  trans-46.7133168.4175.3-172.9-129.200112.2R44 F419 Q421 L472 H527R44-E470 IonicContact CZ-OE2 2.7Å; R44-E470 IonicContact NH1-OE2 3.61Å; R44-E470 PolarHBondContact NH1-OE2 2.86Å; R44-E470 IonicContact NH2-OE2 3.17Å; F419-E470 HydrophobicContact CB-CB 3.82Å; F419-E470 HydrophobicContact CB-CG 3.88Å; F419-E470 HydrophobicContact CD1-CB 4.23Å; F419-E470 HydrophobicContact CG-CB 4.34Å; Q421-E470 HydrophobicContact CG-CG 3.78Å; Q421-E470 VanDerWaalsContact NE2-CD 3.34Å; Q421-E470 PolarHBondContact NE2-OE1 3.18Å; E470-L472 HydrophobicContact CG-CD2 4.25Å; E470-H527 IonicContact OE1-CE1 2.71Å; E470-H527 IonicContact OE1-ND1 3.02Å; E470-H527 PolarHBondContact OE1-ND1 3.33Å; E470-H527 WeakPolarHBondContact OE2-CA 3.49Å; E470-H527 IonicContact OE2-ND1 3.81Å
471P98.6Very high96.1Very high0 Ų039.6 Ų39.60%022%0.222CC..  trans-88.4103.2179.233.4-33.1000112.3Q421 I448 L487Q421-P471 VanDerWaalsContact CB-O 3.29Å; Q421-P471 WeakPolarHBondContact CB-O 3.29Å; Q421-P471 WeakPolarHBondContact CG-O 3.31Å; I448-P471 HydrophobicContact CD1-CB 3.98Å; I448-P471 HydrophobicContact CD1-CG 4.07Å; I448-P471 HydrophobicContact CG2-CB 3.94Å; I448-P471 HydrophobicContact CG2-CG 4.07Å; P471-L487 HydrophobicContact CB-CB 4.19Å; P471-L487 HydrophobicContact CB-CD1 4.2Å
472L98.4Very high96.1Very high8 Ų839.3 Ų39.34%0.04222%0.221CC..EExtended strand (participates in β ladder)trans-79.5128.5177.4-64.9-171.5000111.7L42 Q421 E470 L487 L488L42-L472 HydrophobicContact CD1-CB 4.38Å; L42-L472 HydrophobicContact CD1-CD1 3.29Å; L42-L472 HydrophobicContact CD1-CG 4.17Å; Q421-L472 HydrophobicContact CG-CD2 3.96Å; E470-L472 HydrophobicContact CG-CD2 4.25Å; L472-L487 CarbonylContact O-C 3.58Å; L472-L487 WeakPolarHBondContact O-CA 3.47Å; L472-L488 PolarHBondContact N-O 2.73Å; L472-L488 PolarHBondContact O-N 2.91Å
473F98.6Very high96.1Very high25 Ų2537.4 Ų37.411%0.1121%0.213CC..EExtended strand (participates in β ladder)trans-82.2131.3177.5-178-89.8000112N423 Y436 Q475 E482 L487 A507N423-F473 HydrophobicContact CB-CD1 3.76Å; N423-F473 HydrophobicContact CB-CE1 3.47Å; N423-F473 VanDerWaalsContact CB-CE1 3.47Å; N423-F473 HydrophobicContact CB-CZ 4.02Å; N423-F473 WeakPolarHBondContact ND2-CE1 3.04Å; Y436-F473 HydrophobicContact CD2-CB 4.29Å; Y436-F473 HydrophobicContact CD2-CD2 4.13Å; Y436-F473 HydrophobicContact CE2-CB 4.29Å; Y436-F473 AromaticContact CE2-CD2 3.38Å; Y436-F473 HydrophobicContact CE2-CD2 3.38Å; Y436-F473 AromaticContact CE2-CE2 3.97Å; Y436-F473 HydrophobicContact CE2-CE2 3.97Å; Y436-F473 HydrophobicContact CE2-CG 4.07Å; Y436-F473 AromaticContact CZ-CD2 3.75Å; F473-Q475 HydrophobicContact CE1-CB 3.79Å; F473-Q475 HydrophobicContact CE1-CG 4.47Å; F473-Q475 HydrophobicContact CZ-CB 4.45Å; F473-E482 WeakPolarHBondContact CZ-O 3.43Å; F473-L487 HydrophobicContact CB-CD2 3.98Å; F473-L487 HydrophobicContact CD2-CD2 3.86Å; F473-L487 HydrophobicContact CG-CD2 4.41Å; F473-A507 HydrophobicContact CD2-CB 3.86Å; F473-A507 HydrophobicContact CE2-CB 3.58Å
474V98.3Very high96.2Very high6 Ų636.6 Ų36.64%0.03621%0.21CC..EExtended strand (participates in β ladder)trans-124.6117.3171.4-1750000108.9F37 L38 G485 V486 L488 Y530F37-V474 HydrophobicContact CE2-CG1 4.3Å; L38-V474 HydrophobicContact CD2-CB 4.19Å; L38-V474 HydrophobicContact CD2-CG1 3.82Å; V474-G485 CarbonylContact O-C 3.58Å; V474-G485 WeakPolarHBondContact O-CA 3.44Å; V474-V486 HydrophobicContact CB-CG2 4.08Å; V474-V486 PolarHBondContact N-O 3.42Å; V474-V486 PolarHBondContact O-N 2.85Å; V474-L488 HydrophobicContact CG2-CD1 3.73Å; V474-L488 HydrophobicContact CG2-CG 4.09Å; V474-Y530 HydrophobicContact CB-CD1 4.38Å; V474-Y530 HydrophobicContact CG1-CD1 3.81Å; V474-Y530 HydrophobicContact CG1-CE1 3.72Å; V474-Y530 HydrophobicContact CG2-CD1 3.59Å; V474-Y530 HydrophobicContact CG2-CD2 4.17Å; V474-Y530 HydrophobicContact CG2-CE1 4.11Å; V474-Y530 HydrophobicContact CG2-CG 3.61Å
475Q96.4Very high96.4Very high21 Ų2132.2 Ų32.210%0.09818%0.182CC..EExtended strand (participates in β ladder)trans-69.9140.4-179.8-172.2149.929.500111.6N423 K426 F473N423-Q475 VanDerWaalsContact ND2-CD 3.31Å; N423-Q475 PolarHBondContact ND2-NE2 2.9Å; N423-Q475 PolarHBondContact ND2-OE1 2.82Å; N423-Q475 VanDerWaalsContact ND2-OE1 3.13Å; N423-Q475 PolarHBondContact OD1-OE1 2.63Å; K426-Q475 VanDerWaalsContact NZ-CD 3.29Å; F473-Q475 HydrophobicContact CE1-CB 3.79Å; F473-Q475 HydrophobicContact CE1-CG 4.47Å; F473-Q475 HydrophobicContact CZ-CB 4.45Å
476T95.8Very high96.6Very high44 Ų4430.2 Ų30.227%0.2717%0.174SC..  trans-66.3133.2165-56.40000108.8F37 D478 G479 D484F37-T476 HydrophobicContact CD1-CG2 4.27Å; F37-T476 HydrophobicContact CE1-CG2 4.13Å; T476-D478 PolarHBondContact O-N 3.04Å; T476-D478 VanDerWaalsContact O-N 3.07Å; T476-G479 PolarHBondContact O-N 2.95Å; T476-D484 WeakPolarHBondContact CB-O 3.1Å; T476-D484 PolarHBondContact N-O 3.01Å; T476-D484 PolarHBondContact OG1-O 3.2Å
477P92.6Very high96.7Very high84 Ų8430.1 Ų30.155%0.54517%0.173SC..THydrogen-bonded Turntrans-50.4-39.5-174.3-31.636000115.4F37F37-P477 HydrophobicContact CB-CG 3.83Å; F37-P477 HydrophobicContact CG-CG 4.33Å
478D89.6Confident96.8Very high150 Ų15029.9 Ų29.980%0.80217%0.172SC*.THydrogen-bonded Turntrans-102.617.2179.6-54.1-52.3000112.9T476 V480T476-D478 PolarHBondContact O-N 3.04Å; T476-D478 VanDerWaalsContact O-N 3.07Å; D478-V480 PolarHBondContact O-N 3.29Å
479G90.3Very high96.8Very high8 Ų829.6 Ų29.68%0.08217%0.17CC..  trans-64.3128179.400000111.8K426 T476 D484K426-G479 PolarHBondContact NZ-O 2.79Å; T476-G479 PolarHBondContact O-N 2.95Å; G479-D484 VanDerWaalsContact CA-CB 3.47Å
480V92.3Very high96.8Very high118 Ų11829.7 Ų29.772%0.71517%0.17SC*.  trans-96-46.8-178.3178.40000109.9D478 D484D478-V480 PolarHBondContact O-N 3.29Å; V480-D484 PolarHBondContact N-OD2 3.24Å
481D96.9Very high96.8Very high80 Ų8029.6 Ų29.643%0.42817%0.169SC..SBendtrans-75.3154.4-179.8-62.1-33.7000110.9D483 D484 K508D481-D483 PolarHBondContact O-N 2.88Å; D481-D484 HydrophobicContact CB-CB 4.45Å; D481-D484 PolarHBondContact N-OD2 3.37Å; D481-D484 WeakPolarHBondContact O-CB 3.35Å; D481-D484 PolarHBondContact O-N 2.99Å; D481-D484 VanDerWaalsContact O-N 3.14Å; D481-K508 IonicContact OD2-NZ 2.63Å; D481-K508 PolarHBondContact OD2-NZ 3.15Å
482E97.8Very high96.7Very high15 Ų1530 Ų307%0.0717%0.173CC..THydrogen-bonded Turntrans-56.2-34.7179.6179.3178.9158.600112.4N423 Y427 S433 Y434 F473N423-E482 PolarHBondContact ND2-O 3.33Å; Y427-E482 HydrophobicContact CD1-CG 4.39Å; Y427-E482 HydrophobicContact CD2-CG 3.86Å; Y427-E482 HydrophobicContact CE1-CB 4.42Å; Y427-E482 HydrophobicContact CE1-CG 4.26Å; Y427-E482 HydrophobicContact CE2-CB 3.91Å; Y427-E482 HydrophobicContact CE2-CG 3.71Å; Y427-E482 HydrophobicContact CG-CG 4.2Å; S433-E482 WeakPolarHBondContact CA-OE2 3.39Å; S433-E482 WeakPolarHBondContact CB-OE2 3.16Å; S433-E482 PolarHBondContact N-OE1 2.97Å; S433-E482 PolarHBondContact N-OE2 3.09Å; S433-E482 PolarHBondContact OG-OE2 2.95Å; Y434-E482 HydrophobicContact CD2-CB 3.96Å; Y434-E482 HydrophobicContact CD2-CG 3.96Å; Y434-E482 HydrophobicContact CE2-CB 4.34Å; Y434-E482 PolarHBondContact N-OE1 3.15Å; F473-E482 WeakPolarHBondContact CZ-O 3.43Å
483D98.3Very high96.7Very high11 Ų1129.6 Ų29.66%0.05917%0.171CC..THydrogen-bonded Turntrans-102.414.2-178.861.9-3.3000114.3Y434 Y436 K450 D481 G485 K508Y434-D483 HydrophobicContact CD2-CB 3.84Å; Y434-D483 HydrophobicContact CE2-CB 4.14Å; Y434-D483 HydrophobicContact CG-CB 4.35Å; Y436-D483 WeakPolarHBondContact OH-CA 3.14Å; Y436-D483 WeakPolarHBondContact OH-CB 3.43Å; K450-D483 IonicContact NZ-OD2 2.65Å; K450-D483 PolarHBondContact NZ-OD2 2.88Å; D481-D483 PolarHBondContact O-N 2.88Å; D483-G485 VanDerWaalsContact C-N 3.29Å; D483-G485 PolarHBondContact O-N 3.19Å; D483-K508 HydrophobicContact CB-CG 4.39Å; D483-K508 WeakPolarHBondContact O-CG 3.39Å; D483-K508 WeakPolarHBondContact OD1-CE 3.22Å
484D97.8Very high96.3Very high35 Ų3530 Ų3019%0.18718%0.176CC..  trans-72.481.3170.8-84.3-25.4000111.2T476 G479 V480 D481 K508T476-D484 WeakPolarHBondContact CB-O 3.1Å; T476-D484 PolarHBondContact N-O 3.01Å; T476-D484 PolarHBondContact OG1-O 3.2Å; G479-D484 VanDerWaalsContact CA-CB 3.47Å; V480-D484 PolarHBondContact N-OD2 3.24Å; D481-D484 HydrophobicContact CB-CB 4.45Å; D481-D484 PolarHBondContact N-OD2 3.37Å; D481-D484 WeakPolarHBondContact O-CB 3.35Å; D481-D484 PolarHBondContact O-N 2.99Å; D481-D484 VanDerWaalsContact O-N 3.14Å; D484-K508 WeakPolarHBondContact OD1-CE 3.4Å; D484-K508 IonicContact OD1-NZ 3.54Å; D484-K508 PolarHBondContact OD1-NZ 3.45Å
485G98.1Very high95.5Very high5 Ų533 Ų335%0.05221%0.207CC..EExtended strand (participates in β ladder)trans-172.1-166.6-176.500000112.7V474 D483 A507V474-G485 CarbonylContact O-C 3.58Å; V474-G485 WeakPolarHBondContact O-CA 3.44Å; D483-G485 VanDerWaalsContact C-N 3.29Å; D483-G485 PolarHBondContact O-N 3.19Å; G485-A507 WeakPolarHBondContact O-CB 3.46Å; G485-A507 PolarHBondContact O-N 3.46Å
486V98.7Very high95Very high4 Ų435.1 Ų35.12%0.02423%0.225CC..EExtended strand (participates in β ladder)trans-126.8156.3175.3-62.50000110.8P35 F37 L38 V474 L488 I504 L505 I513P35-V486 HydrophobicContact CG-CG1 4.24Å; F37-V486 HydrophobicContact CE2-CG2 4.33Å; F37-V486 HydrophobicContact CZ-CG1 4.1Å; F37-V486 HydrophobicContact CZ-CG2 4.11Å; L38-V486 HydrophobicContact CD1-CG2 4.17Å; L38-V486 HydrophobicContact CD2-CG2 3.93Å; L38-V486 HydrophobicContact CG-CG2 4.41Å; V474-V486 HydrophobicContact CB-CG2 4.08Å; V474-V486 PolarHBondContact N-O 3.42Å; V474-V486 PolarHBondContact O-N 2.85Å; V486-L488 HydrophobicContact CG2-CD2 4.26Å; V486-I504 HydrophobicContact CB-CG2 3.89Å; V486-I504 HydrophobicContact CG1-CG2 4.08Å; V486-I504 HydrophobicContact CG2-CG2 4.24Å; V486-L505 CarbonylContact C-O 3.47Å; V486-L505 WeakPolarHBondContact CA-O 3.3Å; V486-L505 WeakPolarHBondContact CB-O 3.47Å; V486-I513 HydrophobicContact CG1-CD1 3.54Å
487L98.9Very high94.5Very high0 Ų042.2 Ų42.20%026%0.255CS..EExtended strand (participates in β ladder)trans-105.2133.6169-54.5176.4000109.4Y436 I448 P471 L472 F473 I504 L505 A507 L510Y436-L487 HydrophobicContact CD1-CD1 3.51Å; Y436-L487 HydrophobicContact CD1-CD2 3.74Å; Y436-L487 HydrophobicContact CD1-CG 4.17Å; Y436-L487 HydrophobicContact CD2-CD2 3.81Å; Y436-L487 HydrophobicContact CE1-CD1 4.1Å; Y436-L487 HydrophobicContact CE1-CD2 4.07Å; Y436-L487 HydrophobicContact CE1-CG 4.47Å; Y436-L487 HydrophobicContact CE2-CD2 4.17Å; Y436-L487 HydrophobicContact CG-CD1 4Å; Y436-L487 HydrophobicContact CG-CD2 3.59Å; Y436-L487 HydrophobicContact CG-CG 4.43Å; I448-L487 HydrophobicContact CG2-CD1 4.15Å; P471-L487 HydrophobicContact CB-CB 4.19Å; P471-L487 HydrophobicContact CB-CD1 4.2Å; L472-L487 CarbonylContact O-C 3.58Å; L472-L487 WeakPolarHBondContact O-CA 3.47Å; F473-L487 HydrophobicContact CB-CD2 3.98Å; F473-L487 HydrophobicContact CD2-CD2 3.86Å; F473-L487 HydrophobicContact CG-CD2 4.41Å; L487-I504 WeakPolarHBondContact O-CA 3.31Å; L487-L505 HydrophobicContact CB-CB 4.27Å; L487-L505 PolarHBondContact N-O 3.22Å; L487-L505 PolarHBondContact O-N 2.96Å; L487-A507 HydrophobicContact CD2-CB 4.23Å; L487-A507 HydrophobicContact CG-CB 4.12Å; L487-L510 HydrophobicContact CD1-CD2 3.39Å
488L98.9Very high94.4Very high0 Ų041 Ų410%024%0.24CC..EExtended strand (participates in β ladder)trans-107.4122.8174-53.6-177.6000109L38 L42 F72 L472 V474 V486 M502 I504 Y530L38-L488 HydrophobicContact CD1-CD2 4.07Å; L42-L488 HydrophobicContact CD1-CB 4.41Å; L42-L488 HydrophobicContact CD1-CD1 4.49Å; L42-L488 HydrophobicContact CD2-CB 4.45Å; F72-L488 HydrophobicContact CE2-CD1 4.2Å; F72-L488 HydrophobicContact CZ-CD1 4.22Å; F72-L488 HydrophobicContact CZ-CD2 4.29Å; L472-L488 PolarHBondContact N-O 2.73Å; L472-L488 PolarHBondContact O-N 2.91Å; V474-L488 HydrophobicContact CG2-CD1 3.73Å; V474-L488 HydrophobicContact CG2-CG 4.09Å; V486-L488 HydrophobicContact CG2-CD2 4.26Å; L488-M502 HydrophobicContact CB-SD 4.11Å; L488-I504 HydrophobicContact CD2-CB 4.46Å; L488-I504 HydrophobicContact CD2-CD1 4.42Å; L488-I504 HydrophobicContact CD2-CG1 3.94Å; L488-I504 HydrophobicContact CD2-CG2 4.15Å; L488-Y530 HydrophobicContact CD1-CD2 3.51Å; L488-Y530 HydrophobicContact CD1-CE2 3.76Å; L488-Y530 HydrophobicContact CD1-CG 4.24Å
489T98.7Very high94.6Very high0 Ų034.9 Ų34.90%021%0.208CC..EExtended strand (participates in β ladder)trans-140141.3176.4-179.40000110.8I448 S469 V491 L503I448-T489 HydrophobicContact CD1-CG2 4.32Å; I448-T489 HydrophobicContact CG1-CG2 4.13Å; S469-T489 PolarHBondContact N-OG1 3.2Å; S469-T489 VanDerWaalsContact N-OG1 3.14Å; S469-T489 PolarHBondContact O-OG1 2.77Å; S469-T489 PolarHBondContact OG-OG1 3.34Å; T489-V491 HydrophobicContact CG2-CG2 4.15Å; T489-L503 HydrophobicContact CG2-CB 3.75Å; T489-L503 HydrophobicContact CG2-CD2 3.79Å; T489-L503 HydrophobicContact CG2-CG 4.16Å; T489-L503 PolarHBondContact N-O 2.68Å; T489-L503 VanDerWaalsContact N-O 3.11Å; T489-L503 PolarHBondContact O-N 3.08Å
490I98.7Very high94.9Very high7 Ų734.5 Ų34.54%0.03620%0.204CC..EExtended strand (participates in β ladder)trans-85129170.9-59176.7000107.3L42 R44 H68 F70 P468 S469 M502 I522 T525L42-I490 HydrophobicContact CD2-CG1 4.33Å; R44-I490 HydrophobicContact CB-CD1 4.39Å; R44-I490 HydrophobicContact CG-CD1 4.37Å; H68-I490 HydrophobicContact CB-CD1 4.44Å; F70-I490 HydrophobicContact CD2-CD1 4.16Å; F70-I490 HydrophobicContact CD2-CG1 4.2Å; F70-I490 HydrophobicContact CE2-CD1 3.83Å; F70-I490 HydrophobicContact CE2-CG1 3.83Å; F70-I490 HydrophobicContact CE2-CG2 4.47Å; P468-I490 CarbonylContact C-O 3.45Å; P468-I490 WeakPolarHBondContact CA-O 3.49Å; S469-I490 PolarHBondContact N-O 2.73Å; S469-I490 PolarHBondContact OG-N 3.17Å; S469-I490 PolarHBondContact OG-O 3.18Å; I490-M502 HydrophobicContact CG1-CE 3.54Å; I490-I522 HydrophobicContact CG2-CB 4.28Å; I490-I522 HydrophobicContact CG2-CD1 3.86Å; I490-I522 HydrophobicContact CG2-CG2 3.98Å; I490-T525 HydrophobicContact CD1-CG2 4.48Å
491V98.8Very high95.2Very high0 Ų029 Ų290%017%0.171CC..EExtended strand (participates in β ladder)trans-115124.5176-172.10000109.6W461 P468 T489 A500 Y501 L503W461-V491 HydrophobicContact CH2-CG1 4.27Å; W461-V491 HydrophobicContact CH2-CG2 4.03Å; W461-V491 HydrophobicContact CZ3-CG2 4.32Å; P468-V491 HydrophobicContact CB-CG2 4.14Å; T489-V491 HydrophobicContact CG2-CG2 4.15Å; V491-A500 CarbonylContact O-C 3.49Å; V491-A500 WeakPolarHBondContact O-CA 3.42Å; V491-A500 WeakPolarHBondContact O-CB 3.42Å; V491-Y501 HydrophobicContact CB-CD1 4.44Å; V491-Y501 HydrophobicContact CB-CD2 3.9Å; V491-Y501 HydrophobicContact CB-CE1 4.07Å; V491-Y501 HydrophobicContact CB-CE2 3.46Å; V491-Y501 VanDerWaalsContact CB-CE2 3.46Å; V491-Y501 HydrophobicContact CB-CG 4.36Å; V491-Y501 HydrophobicContact CG1-CE1 4.03Å; V491-Y501 HydrophobicContact CG1-CE2 4Å; V491-Y501 WeakPolarHBondContact CG1-OH 3.37Å; V491-Y501 HydrophobicContact CG2-CD2 4.1Å; V491-Y501 HydrophobicContact CG2-CE2 3.52Å; V491-Y501 PolarHBondContact N-O 3.3Å; V491-Y501 PolarHBondContact O-N 3.03Å; V491-L503 HydrophobicContact CG2-CB 3.84Å; V491-L503 HydrophobicContact CG2-CD2 3.96Å
492A98.1Very high95.3Very high9 Ų925.2 Ų25.27%0.07415%0.15CC..EExtended strand (participates in β ladder)trans-85.9123.6165.400000109I15 S466 Y467 P494I15-A492 HydrophobicContact CG2-CB 3.52Å; S466-A492 WeakPolarHBondContact CA-O 3.11Å; Y467-A492 WeakPolarHBondContact CD2-O 3.22Å; Y467-A492 PolarHBondContact N-O 3.49Å; Y467-A492 PolarHBondContact O-N 3.07Å; A492-P494 VanDerWaalsContact C-CD 3.44Å; A492-P494 WeakPolarHBondContact O-CD 3.5Å
493A96.6Very high95.3Very high0 Ų024.5 Ų24.50%015%0.147CC..  trans-128.964.1-178.700000110.3G495 S496 P499 Y501A493-G495 PolarHBondContact O-N 3.33Å; A493-S496 VanDerWaalsContact O-CB 3.3Å; A493-S496 WeakPolarHBondContact O-CB 3.35Å; A493-S496 PolarHBondContact O-N 3.17Å; A493-P499 CarbonylContact C-O 3.58Å; A493-P499 PolarHBondContact N-O 3.32Å; A493-Y501 HydrophobicContact CB-CD1 4.21Å; A493-Y501 HydrophobicContact CB-CE1 3.67Å
494P91.4Very high95.4Very high34 Ų3424 Ų2422%0.22114%0.144CC..THydrogen-bonded Turntrans-61.1-17.8-169.924.2-36.1000115.4S11 K14 Y467 A492 S496S11-P494 WeakPolarHBondContact O-CG 3.4Å; K14-P494 HydrophobicContact CB-CB 3.82Å; K14-P494 HydrophobicContact CB-CG 4.06Å; K14-P494 HydrophobicContact CG-CB 3.61Å; K14-P494 HydrophobicContact CG-CG 4.13Å; Y467-P494 HydrophobicContact CD2-CG 4.34Å; Y467-P494 HydrophobicContact CE2-CG 3.94Å; A492-P494 VanDerWaalsContact C-CD 3.44Å; A492-P494 WeakPolarHBondContact O-CD 3.5Å; P494-S496 VanDerWaalsContact C-N 3.32Å
495G81.9Confident95.4Very high67 Ų6722.3 Ų22.369%0.69114%0.135SC*.THydrogen-bonded Turntrans-81.4-7.2173.300000114.6A493A493-G495 PolarHBondContact O-N 3.33Å
496S86.2Confident95.4Very high67 Ų6724.1 Ų24.147%0.46914%0.144SC..SBendtrans-94159.3-177.3-61.60000112A493 P494 R498A493-S496 VanDerWaalsContact O-CB 3.3Å; A493-S496 WeakPolarHBondContact O-CB 3.35Å; A493-S496 PolarHBondContact O-N 3.17Å; P494-S496 VanDerWaalsContact C-N 3.32Å; S496-R498 WeakPolarHBondContact CB-O 3.31Å; S496-R498 PolarHBondContact O-N 3.5Å
497Q84.6Confident95.4Very high193 Ų19324 Ų2490%0.90214%0.143SC*.SBendtrans-56.3-35.5174.1-176179.66.700111.9
498R90Very high95.4Very high58 Ų5827.3 Ų27.322%0.21916%0.157CC..SBendtrans-107.7111.5172.1-70.6-175.3-176.41300.2108.7T29 S496 A500 E517 V518T29-R498 PolarHBondContact OG1-NH2 3.23Å; S496-R498 WeakPolarHBondContact CB-O 3.31Å; S496-R498 PolarHBondContact O-N 3.5Å; R498-A500 PolarHBondContact O-N 3.14Å; R498-E517 HydrophobicContact CB-CB 4Å; R498-E517 HydrophobicContact CG-CB 4.27Å; R498-E517 IonicContact CZ-OE2 3.59Å; R498-E517 IonicContact NH1-OE2 2.72Å; R498-E517 PolarHBondContact NH1-OE2 3.42Å; R498-V518 WeakPolarHBondContact CB-O 3.46Å
499P93.2Very high95.4Very high22 Ų2231.1 Ų31.114%0.14318%0.178CC..SBendtrans-76.3-4.4-164.930.1-37.9000114.4A493 V518 C520A493-P499 CarbonylContact C-O 3.58Å; A493-P499 PolarHBondContact N-O 3.32Å; P499-V518 WeakPolarHBondContact CD-O 3.45Å; P499-C520 VanDerWaalsContact CG-C 3.46Å
500A97.6Very high95.4Very high0 Ų031.4 Ų31.40%018%0.179CC..EExtended strand (participates in β ladder)trans-156.7160171.800000112.2V491 R498 V518 I522V491-A500 CarbonylContact O-C 3.49Å; V491-A500 WeakPolarHBondContact O-CA 3.42Å; V491-A500 WeakPolarHBondContact O-CB 3.42Å; R498-A500 PolarHBondContact O-N 3.14Å; A500-V518 HydrophobicContact CB-CG2 3.84Å; A500-V518 VanDerWaalsContact O-CG2 3.27Å; A500-V518 WeakPolarHBondContact O-CG2 3.34Å; A500-V518 PolarHBondContact O-N 3.01Å; A500-I522 HydrophobicContact CB-CB 3.99Å; A500-I522 HydrophobicContact CB-CD1 3.76Å; A500-I522 HydrophobicContact CB-CG1 3.62Å
501Y98.4Very high95.4Very high2 Ų233.5 Ų33.51%0.00820%0.195CC..EExtended strand (participates in β ladder)trans-153.7154.1176.255-95.3000112.8E463 V491 A493 L503 R515 A516E463-Y501 PolarHBondContact OE2-OH 2.81Å; E463-Y501 VanDerWaalsContact OE2-OH 3.09Å; V491-Y501 HydrophobicContact CB-CD1 4.44Å; V491-Y501 HydrophobicContact CB-CD2 3.9Å; V491-Y501 HydrophobicContact CB-CE1 4.07Å; V491-Y501 HydrophobicContact CB-CE2 3.46Å; V491-Y501 VanDerWaalsContact CB-CE2 3.46Å; V491-Y501 HydrophobicContact CB-CG 4.36Å; V491-Y501 HydrophobicContact CG1-CE1 4.03Å; V491-Y501 HydrophobicContact CG1-CE2 4Å; V491-Y501 WeakPolarHBondContact CG1-OH 3.37Å; V491-Y501 HydrophobicContact CG2-CD2 4.1Å; V491-Y501 HydrophobicContact CG2-CE2 3.52Å; V491-Y501 PolarHBondContact N-O 3.3Å; V491-Y501 PolarHBondContact O-N 3.03Å; A493-Y501 HydrophobicContact CB-CD1 4.21Å; A493-Y501 HydrophobicContact CB-CE1 3.67Å; Y501-L503 HydrophobicContact CD2-CB 4.01Å; Y501-L503 HydrophobicContact CE2-CB 3.89Å; Y501-L503 HydrophobicContact CE2-CD1 4.12Å; Y501-L503 HydrophobicContact CE2-CD2 4.49Å; Y501-L503 HydrophobicContact CE2-CG 4.4Å; Y501-R515 HydrophobicContact CD2-CB 3.89Å; Y501-R515 HydrophobicContact CG-CB 4.4Å; Y501-R515 PolarHBondContact OH-NH1 3.34Å; Y501-A516 CarbonylContact C-O 3.6Å; Y501-A516 WeakPolarHBondContact CA-O 3.4Å
502M98.6Very high95.3Very high0 Ų036.8 Ų36.80%021%0.21CC..EExtended strand (participates in β ladder)trans-82.2118.8163.4172.651.949.300109L42 F70 F72 L488 I490 R515 A516L42-M502 HydrophobicContact CD2-CE 3.07Å; L42-M502 HydrophobicContact CD2-SD 3.97Å; L42-M502 HydrophobicContact CG-CE 4.45Å; F70-M502 HydrophobicContact CB-CE 4.02Å; F70-M502 HydrophobicContact CD1-CB 3.58Å; F70-M502 HydrophobicContact CD1-CE 4.27Å; F70-M502 HydrophobicContact CD1-CG 4.25Å; F70-M502 HydrophobicContact CD2-CE 3.43Å; F70-M502 VanDerWaalsContact CD2-CE 3.43Å; F70-M502 HydrophobicContact CE1-CB 3.58Å; F70-M502 HydrophobicContact CE2-CE 3.86Å; F70-M502 HydrophobicContact CG-CB 4.05Å; F70-M502 HydrophobicContact CG-CE 3.65Å; F70-M502 HydrophobicContact CG-CG 4.37Å; F70-M502 HydrophobicContact CZ-CB 4.07Å; F70-M502 HydrophobicContact CZ-CE 4.44Å; F72-M502 HydrophobicContact CE1-CG 4.22Å; F72-M502 HydrophobicContact CZ-CG 3.78Å; F72-M502 HydrophobicContact CZ-SD 4.23Å; L488-M502 HydrophobicContact CB-SD 4.11Å; I490-M502 HydrophobicContact CG1-CE 3.54Å; M502-R515 CarbonylContact O-C 3.55Å; M502-R515 WeakPolarHBondContact O-CA 3.42Å; M502-A516 HydrophobicContact CB-CB 4.16Å; M502-A516 PolarHBondContact N-O 3.39Å; M502-A516 PolarHBondContact O-N 3.21Å
503L98.8Very high95.4Very high0 Ų038.9 Ų38.90%022%0.219CC..EExtended strand (participates in β ladder)trans-99.9136.4178.1-17966000110.8W461 T489 V491 Y501 L505 E512 R515W461-L503 HydrophobicContact CD2-CD2 3.77Å; W461-L503 VanDerWaalsContact CE2-CD2 3.47Å; W461-L503 HydrophobicContact CE3-CD2 3.88Å; W461-L503 HydrophobicContact CH2-CD2 3.5Å; W461-L503 HydrophobicContact CZ2-CD1 4.37Å; W461-L503 HydrophobicContact CZ2-CD2 3.34Å; W461-L503 HydrophobicContact CZ2-CG 4.49Å; W461-L503 HydrophobicContact CZ3-CD2 3.76Å; T489-L503 HydrophobicContact CG2-CB 3.75Å; T489-L503 HydrophobicContact CG2-CD2 3.79Å; T489-L503 HydrophobicContact CG2-CG 4.16Å; T489-L503 PolarHBondContact N-O 2.68Å; T489-L503 VanDerWaalsContact N-O 3.11Å; T489-L503 PolarHBondContact O-N 3.08Å; V491-L503 HydrophobicContact CG2-CB 3.84Å; V491-L503 HydrophobicContact CG2-CD2 3.96Å; Y501-L503 HydrophobicContact CD2-CB 4.01Å; Y501-L503 HydrophobicContact CE2-CB 3.89Å; Y501-L503 HydrophobicContact CE2-CD1 4.12Å; Y501-L503 HydrophobicContact CE2-CD2 4.49Å; Y501-L503 HydrophobicContact CE2-CG 4.4Å; L503-L505 HydrophobicContact CD1-CD2 3.97Å; L503-L505 HydrophobicContact CD2-CD1 4.12Å; L503-L505 HydrophobicContact CD2-CD2 3.79Å; L503-L505 HydrophobicContact CD2-CG 3.93Å; L503-L505 HydrophobicContact CG-CD2 3.81Å; L503-L505 HydrophobicContact CG-CG 3.98Å; L503-E512 HydrophobicContact CD1-CB 4.46Å; L503-E512 HydrophobicContact CD1-CG 3.7Å; L503-R515 HydrophobicContact CD1-CB 4.44Å
504I98.9Very high95.5Very high0 Ų038.9 Ų38.90%022%0.219CC..EExtended strand (participates in β ladder)trans-118.2113.1175.6-49.6-177.6000108.4I34 L38 F72 V486 L487 L488 I513 A514I34-I504 HydrophobicContact CD1-CD1 3.49Å; I34-I504 VanDerWaalsContact CD1-CD1 3.49Å; I34-I504 HydrophobicContact CG2-CD1 4.2Å; L38-I504 HydrophobicContact CD1-CD1 3.84Å; L38-I504 HydrophobicContact CD1-CG2 4.32Å; F72-I504 HydrophobicContact CE1-CD1 3.98Å; V486-I504 HydrophobicContact CB-CG2 3.89Å; V486-I504 HydrophobicContact CG1-CG2 4.08Å; V486-I504 HydrophobicContact CG2-CG2 4.24Å; L487-I504 WeakPolarHBondContact O-CA 3.31Å; L488-I504 HydrophobicContact CD2-CB 4.46Å; L488-I504 HydrophobicContact CD2-CD1 4.42Å; L488-I504 HydrophobicContact CD2-CG1 3.94Å; L488-I504 HydrophobicContact CD2-CG2 4.15Å; I504-I513 HydrophobicContact CG2-CB 4.29Å; I504-I513 HydrophobicContact CG2-CD1 4.41Å; I504-I513 PolarHBondContact O-N 2.71Å; I504-A514 HydrophobicContact CD1-CB 4.32Å; I504-A514 PolarHBondContact N-O 3.27Å; I504-A514 PolarHBondContact O-N 3.46Å
505L98.9Very high95.8Very high0 Ų038.8 Ų38.80%022%0.215CC..EExtended strand (participates in β ladder)trans-105.6146.6177-58.2179.4000110.7I448 W461 V486 L487 L503 A507 L510 S511 E512I448-L505 HydrophobicContact CB-CD1 4.24Å; I448-L505 HydrophobicContact CG1-CD1 4.41Å; I448-L505 HydrophobicContact CG2-CD1 4.15Å; W461-L505 HydrophobicContact CB-CD1 3.78Å; W461-L505 HydrophobicContact CD2-CD1 4.26Å; W461-L505 HydrophobicContact CD2-CD2 4.5Å; W461-L505 HydrophobicContact CG-CD1 3.84Å; W461-L505 HydrophobicContact CG-CD2 4.04Å; V486-L505 CarbonylContact C-O 3.47Å; V486-L505 WeakPolarHBondContact CA-O 3.3Å; V486-L505 WeakPolarHBondContact CB-O 3.47Å; L487-L505 HydrophobicContact CB-CB 4.27Å; L487-L505 PolarHBondContact N-O 3.22Å; L487-L505 PolarHBondContact O-N 2.96Å; L503-L505 HydrophobicContact CD1-CD2 3.97Å; L503-L505 HydrophobicContact CD2-CD1 4.12Å; L503-L505 HydrophobicContact CD2-CD2 3.79Å; L503-L505 HydrophobicContact CD2-CG 3.93Å; L503-L505 HydrophobicContact CG-CD2 3.81Å; L503-L505 HydrophobicContact CG-CG 3.98Å; L505-A507 PolarHBondContact O-N 2.89Å; L505-L510 HydrophobicContact CD1-CD2 4.4Å; L505-S511 CarbonylContact C-O 3.56Å; L505-S511 WeakPolarHBondContact CA-O 3.27Å; L505-E512 HydrophobicContact CD2-CB 4.03Å
506N98.6Very high96.6Very high44 Ų4435.7 Ų35.724%0.23518%0.182CC..EExtended strand (participates in β ladder)trans-66.9122.2163.6-178-10.5000108.9K508 D509 L510 S511 I513N506-K508 PolarHBondContact O-N 3.16Å; N506-K508 WeakPolarHBondContact OD1-CB 3.36Å; N506-K508 PolarHBondContact OD1-N 3.49Å; N506-D509 WeakPolarHBondContact CB-OD1 3.36Å; N506-D509 PolarHBondContact ND2-OD1 2.88Å; N506-L510 WeakPolarHBondContact O-CA 3.43Å; N506-L510 PolarHBondContact O-N 3.27Å; N506-S511 WeakPolarHBondContact CB-OG 3.42Å; N506-S511 PolarHBondContact N-O 2.98Å; N506-I513 HydrophobicContact CB-CD1 3.89Å; N506-I513 HydrophobicContact CB-CG1 4.08Å
507A98.7Very high97.2Very high0 Ų034.2 Ų34.20%017%0.168CC..THydrogen-bonded Turntrans-68.9-16.5-177.500000113.1Y436 K450 F473 G485 L487 L505Y436-A507 HydrophobicContact CE1-CB 4.05Å; Y436-A507 WeakPolarHBondContact CE1-O 3.45Å; K450-A507 WeakPolarHBondContact CD-O 3.08Å; K450-A507 WeakPolarHBondContact CE-O 3.23Å; K450-A507 PolarHBondContact NZ-O 3.08Å; F473-A507 HydrophobicContact CD2-CB 3.86Å; F473-A507 HydrophobicContact CE2-CB 3.58Å; G485-A507 WeakPolarHBondContact O-CB 3.46Å; G485-A507 PolarHBondContact O-N 3.46Å; L487-A507 HydrophobicContact CD2-CB 4.23Å; L487-A507 HydrophobicContact CG-CB 4.12Å; L505-A507 PolarHBondContact O-N 2.89Å
508K98.1Very high97.7Very high70 Ų7025.1 Ų25.130%0.30413%0.126SC..THydrogen-bonded Turntrans-70.3-49.4177.2-73.9-165151.6167.30113.3K450 D481 D483 D484 N506K450-K508 PolarHBondContact NZ-O 2.94Å; D481-K508 IonicContact OD2-NZ 2.63Å; D481-K508 PolarHBondContact OD2-NZ 3.15Å; D483-K508 HydrophobicContact CB-CG 4.39Å; D483-K508 WeakPolarHBondContact O-CG 3.39Å; D483-K508 WeakPolarHBondContact OD1-CE 3.22Å; D484-K508 WeakPolarHBondContact OD1-CE 3.4Å; D484-K508 IonicContact OD1-NZ 3.54Å; D484-K508 PolarHBondContact OD1-NZ 3.45Å; N506-K508 PolarHBondContact O-N 3.16Å; N506-K508 WeakPolarHBondContact OD1-CB 3.36Å; N506-K508 PolarHBondContact OD1-N 3.49Å
509D97.9Very high98Very high81 Ų8129.8 Ų29.843%0.43315%0.15SC..THydrogen-bonded Turntrans-127.41-169.660.98.7000114.2N506 S511N506-D509 WeakPolarHBondContact CB-OD1 3.36Å; N506-D509 PolarHBondContact ND2-OD1 2.88Å; D509-S511 VanDerWaalsContact CG-OG 3.3Å; D509-S511 PolarHBondContact O-N 3.32Å; D509-S511 WeakPolarHBondContact OD1-CB 3.26Å; D509-S511 PolarHBondContact OD1-N 2.66Å; D509-S511 PolarHBondContact OD1-OG 3.14Å; D509-S511 PolarHBondContact OD2-OG 2.96Å
510L98.6Very high98.1Very high6 Ų629.9 Ų29.93%0.03115%0.151CC..  trans59.520.6-173.3-54.9-175.2000114.4I448 K450 W459 W461 L487 L505 N506I448-L510 HydrophobicContact CG2-CD1 4.45Å; I448-L510 HydrophobicContact CG2-CD2 4.39Å; K450-L510 HydrophobicContact CB-CD1 3.95Å; K450-L510 HydrophobicContact CB-CD2 4.21Å; K450-L510 HydrophobicContact CB-CG 4.14Å; W459-L510 HydrophobicContact CB-CD1 3.79Å; W459-L510 HydrophobicContact CB-CG 4.05Å; W459-L510 WeakPolarHBondContact O-CD1 3.45Å; W461-L510 HydrophobicContact CB-CB 4.16Å; L487-L510 HydrophobicContact CD1-CD2 3.39Å; L505-L510 HydrophobicContact CD1-CD2 4.4Å; N506-L510 WeakPolarHBondContact O-CA 3.43Å; N506-L510 PolarHBondContact O-N 3.27Å
511S98.6Very high97.9Very high51 Ų5132.4 Ų32.436%0.35717%0.169SC..  trans-67.3142.7169.761.30000110.6L505 N506 D509L505-S511 CarbonylContact C-O 3.56Å; L505-S511 WeakPolarHBondContact CA-O 3.27Å; N506-S511 WeakPolarHBondContact CB-OG 3.42Å; N506-S511 PolarHBondContact N-O 2.98Å; D509-S511 VanDerWaalsContact CG-OG 3.3Å; D509-S511 PolarHBondContact O-N 3.32Å; D509-S511 WeakPolarHBondContact OD1-CB 3.26Å; D509-S511 PolarHBondContact OD1-N 2.66Å; D509-S511 PolarHBondContact OD1-OG 3.14Å; D509-S511 PolarHBondContact OD2-OG 2.96Å
512E98.7Very high97.9Very high68 Ų6832.5 Ų32.532%0.31817%0.169SC..EExtended strand (participates in β ladder)trans-74.1129.8176.6-179.6176.3157.100111.8L503 L505 R515L503-E512 HydrophobicContact CD1-CB 4.46Å; L503-E512 HydrophobicContact CD1-CG 3.7Å; L505-E512 HydrophobicContact CD2-CB 4.03Å; E512-R515 VanDerWaalsContact CD-NH2 3.3Å; E512-R515 IonicContact OE1-CZ 2.8Å; E512-R515 IonicContact OE1-NE 3.65Å; E512-R515 PolarHBondContact OE1-NE 2.81Å; E512-R515 IonicContact OE1-NH2 2.73Å; E512-R515 PolarHBondContact OE1-NH2 2.91Å; E512-R515 IonicContact OE2-CZ 3.22Å; E512-R515 IonicContact OE2-NE 2.78Å; E512-R515 IonicContact OE2-NH2 3.9Å; E512-R515 PolarHBondContact OE2-NH2 3.47Å
513I98.6Very high97.9Very high54 Ų5432.8 Ų32.828%0.27717%0.171SC..EExtended strand (participates in β ladder)trans-95.4-46.1175.5-64.1172.8000110.4R33 P35 V486 I504 N506R33-I513 PolarHBondContact N-O 2.84Å; R33-I513 WeakPolarHBondContact O-CG2 2.98Å; P35-I513 HydrophobicContact CG-CG2 4.09Å; V486-I513 HydrophobicContact CG1-CD1 3.54Å; I504-I513 HydrophobicContact CG2-CB 4.29Å; I504-I513 HydrophobicContact CG2-CD1 4.41Å; I504-I513 PolarHBondContact O-N 2.71Å; N506-I513 HydrophobicContact CB-CD1 3.89Å; N506-I513 HydrophobicContact CB-CG1 4.08Å
514A98.6Very high97.9Very high0 Ų033.9 Ų33.90%018%0.178CC..EExtended strand (participates in β ladder)trans-163.2160.8-177.400000111.4T31 I34 I504T31-A514 CarbonylContact O-C 3.12Å; T31-A514 WeakPolarHBondContact O-CA 3.47Å; T31-A514 WeakPolarHBondContact O-CB 3.11Å; I34-A514 HydrophobicContact CD1-CB 3.78Å; I504-A514 HydrophobicContact CD1-CB 4.32Å; I504-A514 PolarHBondContact N-O 3.27Å; I504-A514 PolarHBondContact O-N 3.46Å
515R98.2Very high97.8Very high32 Ų3234.3 Ų34.312%0.12118%0.18CC..EExtended strand (participates in β ladder)trans-135146.1164.564.2179.473-170.53.3111.4V30 T31 E463 Y501 M502 L503 E512 E517V30-R515 WeakPolarHBondContact CA-O 3.2Å; T31-R515 PolarHBondContact N-O 3.2Å; T31-R515 PolarHBondContact O-N 2.81Å; E463-R515 IonicContact OE1-CZ 2.83Å; E463-R515 IonicContact OE1-NH1 2.76Å; E463-R515 IonicContact OE1-NH2 3.38Å; E463-R515 PolarHBondContact OE1-NH2 2.8Å; E463-R515 IonicContact OE2-CZ 3.81Å; E463-R515 IonicContact OE2-NH1 3.15Å; E463-R515 PolarHBondContact OE2-NH1 3.05Å; E463-R515 IonicContact OE2-NH2 2.74Å; E463-R515 PolarHBondContact OE2-NH2 3.49Å; Y501-R515 HydrophobicContact CD2-CB 3.89Å; Y501-R515 HydrophobicContact CG-CB 4.4Å; Y501-R515 PolarHBondContact OH-NH1 3.34Å; M502-R515 CarbonylContact O-C 3.55Å; M502-R515 WeakPolarHBondContact O-CA 3.42Å; L503-R515 HydrophobicContact CD1-CB 4.44Å; E512-R515 VanDerWaalsContact CD-NH2 3.3Å; E512-R515 IonicContact OE1-CZ 2.8Å; E512-R515 IonicContact OE1-NE 3.65Å; E512-R515 PolarHBondContact OE1-NE 2.81Å; E512-R515 IonicContact OE1-NH2 2.73Å; E512-R515 PolarHBondContact OE1-NH2 2.91Å; E512-R515 IonicContact OE2-CZ 3.22Å; E512-R515 IonicContact OE2-NE 2.78Å; E512-R515 IonicContact OE2-NH2 3.9Å; E512-R515 PolarHBondContact OE2-NH2 3.47Å; R515-E517 HydrophobicContact CG-CG 4.08Å
516A98.4Very high97.8Very high1 Ų134.5 Ų34.51%0.00818%0.181CC..EExtended strand (participates in β ladder)trans-117.1102.4175.600000109.2T28 V30 V77 Y501 M502T28-A516 HydrophobicContact CG2-CB 4.2Å; T28-A516 WeakPolarHBondContact OG1-CB 3.26Å; V30-A516 HydrophobicContact CG2-CB 4.26Å; V77-A516 HydrophobicContact CB-CB 3.72Å; V77-A516 HydrophobicContact CG1-CB 3.94Å; V77-A516 HydrophobicContact CG2-CB 3.92Å; Y501-A516 CarbonylContact C-O 3.6Å; Y501-A516 WeakPolarHBondContact CA-O 3.4Å; M502-A516 HydrophobicContact CB-CB 4.16Å; M502-A516 PolarHBondContact N-O 3.39Å; M502-A516 PolarHBondContact O-N 3.21Å
517E98.3Very high97.8Very high37 Ų3732.8 Ų32.817%0.17317%0.171CC..EExtended strand (participates in β ladder)trans-90.7143.8-168.3-52.2177.3125.700112.4T28 T29 R498 R515T28-E517 CarbonylContact C-O 3.58Å; T28-E517 VanDerWaalsContact CA-O 3.25Å; T28-E517 WeakPolarHBondContact CA-O 3.25Å; T28-E517 WeakPolarHBondContact CB-O 3.42Å; T29-E517 PolarHBondContact N-O 3.05Å; T29-E517 PolarHBondContact O-N 3.48Å; R498-E517 HydrophobicContact CB-CB 4Å; R498-E517 HydrophobicContact CG-CB 4.27Å; R498-E517 IonicContact CZ-OE2 3.59Å; R498-E517 IonicContact NH1-OE2 2.72Å; R498-E517 PolarHBondContact NH1-OE2 3.42Å; R515-E517 HydrophobicContact CG-CG 4.08Å
518V97Very high97.8Very high2 Ų233.2 Ų33.21%0.01218%0.176CC..EExtended strand (participates in β ladder)trans-121.5153.3179.2-660000111.5T28 F70 Y79 R498 P499 A500 C520 I522T28-V518 HydrophobicContact CG2-CG1 3.69Å; F70-V518 HydrophobicContact CE1-CG1 4.17Å; F70-V518 HydrophobicContact CZ-CG1 4.46Å; Y79-V518 HydrophobicContact CD1-CB 4.45Å; Y79-V518 HydrophobicContact CD1-CG1 3.94Å; Y79-V518 HydrophobicContact CG-CG1 3.97Å; R498-V518 WeakPolarHBondContact CB-O 3.46Å; P499-V518 WeakPolarHBondContact CD-O 3.45Å; A500-V518 HydrophobicContact CB-CG2 3.84Å; A500-V518 VanDerWaalsContact O-CG2 3.27Å; A500-V518 WeakPolarHBondContact O-CG2 3.34Å; A500-V518 PolarHBondContact O-N 3.01Å; V518-C520 VanDerWaalsContact C-N 3.3Å; V518-C520 WeakPolarHBondContact CG2-O 3.39Å; V518-C520 PolarHBondContact O-N 2.73Å; V518-I522 HydrophobicContact CG2-CD1 3.99Å; V518-I522 HydrophobicContact CG2-CG1 4.41Å
519E94.6Very high97.7Very high156 Ų15631.6 Ų31.673%0.72917%0.17SC*.SBendtrans-89.59.1-178.1-60.5-172.1165.800113.6
520C95Very high97.7Very high23 Ų2329.4 Ų29.416%0.15516%0.156CC..SBendtrans-126.6146.2179.565.40000111.7P499 V518P499-C520 VanDerWaalsContact CG-C 3.46Å; V518-C520 VanDerWaalsContact C-N 3.3Å; V518-C520 WeakPolarHBondContact CG2-O 3.39Å; V518-C520 PolarHBondContact O-N 2.73Å
521S95.2Very high97.6Very high54 Ų5431.4 Ų31.438%0.37816%0.164SC..  trans-66.8144.9177.3-550000110.7R81R81-S521 PolarHBondContact NH1-O 3.45Å
522I97.9Very high97.2Very high3 Ų336.8 Ų36.82%0.01518%0.184CC..  trans-118.2123.3174.1-56-179.7000108.1F70 Y79 I490 A500 V518F70-I522 HydrophobicContact CE2-CD1 3.98Å; F70-I522 HydrophobicContact CZ-CD1 3.78Å; Y79-I522 HydrophobicContact CD2-CD1 4.34Å; Y79-I522 HydrophobicContact CE1-CD1 3.99Å; Y79-I522 HydrophobicContact CE1-CG1 4.13Å; Y79-I522 HydrophobicContact CE2-CD1 3.79Å; Y79-I522 HydrophobicContact CE2-CG1 4.49Å; I490-I522 HydrophobicContact CG2-CB 4.28Å; I490-I522 HydrophobicContact CG2-CD1 3.86Å; I490-I522 HydrophobicContact CG2-CG2 3.98Å; A500-I522 HydrophobicContact CB-CB 3.99Å; A500-I522 HydrophobicContact CB-CD1 3.76Å; A500-I522 HydrophobicContact CB-CG1 3.62Å; V518-I522 HydrophobicContact CG2-CD1 3.99Å; V518-I522 HydrophobicContact CG2-CG1 4.41Å
523P97.9Very high97.1Very high7 Ų735.2 Ų35.25%0.04518%0.177CC..  trans-69.3174.7174.931.1-36.3000111.4I15 C19 P47 F50 L66I15-P523 CarbonylContact O-C 3.54Å; I15-P523 WeakPolarHBondContact O-CA 3.37Å; I15-P523 WeakPolarHBondContact O-CB 3.48Å; C19-P523 VanDerWaalsContact SG-CD 3.6Å; P47-P523 WeakPolarHBondContact O-CB 3.29Å; P47-P523 WeakPolarHBondContact O-CG 3.47Å; F50-P523 HydrophobicContact CE2-CB 4.22Å; F50-P523 HydrophobicContact CZ-CB 4.44Å; L66-P523 HydrophobicContact CD2-CG 4.02Å
524V98.2Very high97.1Very high23 Ų2334.2 Ų34.214%0.13917%0.172CC..  trans-56.7140.1176.664.60000111.1I15 F16 P47 L60 F526I15-V524 HydrophobicContact CB-CB 4.25Å; I15-V524 HydrophobicContact CG1-CB 4.1Å; I15-V524 PolarHBondContact O-N 2.88Å; F16-V524 HydrophobicContact CD1-CG1 4.11Å; F16-V524 HydrophobicContact CE1-CB 4.47Å; F16-V524 HydrophobicContact CE1-CG1 4.22Å; P47-V524 HydrophobicContact CG-CG1 3.76Å; L60-V524 HydrophobicContact CD1-CG1 3.93Å; V524-F526 HydrophobicContact CG2-CE1 4.42Å
525T98.4Very high97Very high8 Ų836.1 Ų36.15%0.04918%0.182CC..  trans-125.2144.1172.359.40000109.5R44 L45 H68 S469 I490R44-T525 HydrophobicContact CB-CG2 4.27Å; R44-T525 PolarHBondContact NE-OG1 2.93Å; R44-T525 PolarHBondContact NH2-O 2.48Å; R44-T525 PolarHBondContact NH2-OG1 3.25Å; L45-T525 CarbonylContact O-C 3.48Å; L45-T525 WeakPolarHBondContact O-CA 3.29Å; L45-T525 WeakPolarHBondContact O-CB 3.49Å; H68-T525 VanDerWaalsContact CD2-CG2 3.47Å; H68-T525 WeakPolarHBondContact CD2-CG2 3.34Å; S469-T525 WeakPolarHBondContact CB-OG1 3.41Å; I490-T525 HydrophobicContact CD1-CG2 4.48Å
526F98.4Very high96.9Very high5 Ų536.4 Ų36.42%0.02219%0.185CC..  trans-93.7-71.3-176.7-56.9-50.9000112R44 L45 P47 L60 F61 L134 F419 V524R44-F526 PolarHBondContact NH2-O 3.08Å; L45-F526 PolarHBondContact O-N 3.05Å; P47-F526 HydrophobicContact CG-CE2 4.36Å; P47-F526 HydrophobicContact CG-CZ 4.16Å; L60-F526 HydrophobicContact CD1-CE1 4.12Å; L60-F526 HydrophobicContact CD1-CZ 4.01Å; L60-F526 HydrophobicContact CD2-CE1 3.99Å; L60-F526 HydrophobicContact CD2-CZ 4.36Å; L60-F526 HydrophobicContact CG-CE1 3.9Å; L60-F526 HydrophobicContact CG-CZ 3.77Å; F61-F526 HydrophobicContact CD1-CD2 4.49Å; F61-F526 HydrophobicContact CD1-CE1 4.29Å; F61-F526 AromaticContact CD1-CE2 3.71Å; F61-F526 HydrophobicContact CD1-CE2 3.71Å; F61-F526 AromaticContact CD1-CZ 3.61Å; F61-F526 HydrophobicContact CD1-CZ 3.61Å; F61-F526 HydrophobicContact CE1-CD1 4.35Å; F61-F526 HydrophobicContact CE1-CD2 4.49Å; F61-F526 AromaticContact CE1-CE1 3.84Å; F61-F526 HydrophobicContact CE1-CE1 3.84Å; F61-F526 AromaticContact CE1-CE2 3.97Å; F61-F526 HydrophobicContact CE1-CE2 3.97Å; F61-F526 AromaticContact CE1-CZ 3.64Å; F61-F526 HydrophobicContact CE1-CZ 3.64Å; L134-F526 HydrophobicContact CD1-CE2 3.89Å; L134-F526 HydrophobicContact CG-CE2 4.15Å; F419-F526 WeakPolarHBondContact CD1-O 3.41Å; F419-F526 HydrophobicContact CE1-CB 4.15Å; F419-F526 HydrophobicContact CE1-CD1 4.32Å; F419-F526 HydrophobicContact CZ-CD1 4.33Å; V524-F526 HydrophobicContact CG2-CE1 4.42Å
527H98.8Very high96.8Very high7 Ų738.6 Ų38.63%0.03220%0.196CC..  trans-130.2170.8-177.3-55.2-71000112.8R44 L45 V135 N136 H181 H314 F419 E470R44-H527 WeakPolarHBondContact CA-O 3.43Å; L45-H527 PolarHBondContact N-O 3.26Å; V135-H527 WeakPolarHBondContact O-CB 3.32Å; V135-H527 PolarHBondContact O-N 3.42Å; V135-H527 VanDerWaalsContact O-N 3.16Å; N136-H527 HydrophobicContact CB-CB 3.8Å; N136-H527 VanDerWaalsContact CG-CB 3.44Å; N136-H527 WeakPolarHBondContact OD1-CB 3.14Å; H181-H527 AromaticContact CE1-CD2 3.5Å; H181-H527 AromaticContact CE1-CE1 3.4Å; H181-H527 PolarHBondContact CE1-CE1 3.23Å; H181-H527 VanDerWaalsContact CE1-CE1 3.4Å; H181-H527 AromaticContact CE1-CG 3.74Å; H181-H527 AromaticContact CE1-ND1 3.68Å; H181-H527 AromaticContact CE1-NE2 3.31Å; H181-H527 PolarHBondContact CE1-NE2 3.29Å; H181-H527 VanDerWaalsContact CE1-NE2 3.31Å; H181-H527 AromaticContact NE2-CD2 3.68Å; H181-H527 AromaticContact NE2-CE1 3.96Å; H181-H527 AromaticContact NE2-NE2 3.43Å; H181-H527 PolarHBondContact NE2-NE2 3.46Å; H314-H527 AromaticContact CE1-CE1 3.91Å; H314-H527 AromaticContact NE2-CE1 3.25Å; H314-H527 PolarHBondContact NE2-CE1 3.19Å; H314-H527 VanDerWaalsContact NE2-CE1 3.25Å; H314-H527 AromaticContact NE2-NE2 3.35Å; H314-H527 PolarHBondContact NE2-NE2 3.49Å; F419-H527 AromaticContact CD1-CE1 3.23Å; F419-H527 WeakPolarHBondContact CD1-CE1 3.33Å; F419-H527 AromaticContact CD1-ND1 3.82Å; F419-H527 AromaticContact CD1-NE2 3.85Å; F419-H527 AromaticContact CE1-CE1 3.57Å; F419-H527 AromaticContact CE1-NE2 3.69Å; E470-H527 IonicContact OE1-CE1 2.71Å; E470-H527 IonicContact OE1-ND1 3.02Å; E470-H527 PolarHBondContact OE1-ND1 3.33Å; E470-H527 WeakPolarHBondContact OE2-CA 3.49Å; E470-H527 IonicContact OE2-ND1 3.81Å
528G97.6Very high96.7Very high10 Ų1038.7 Ų38.710%0.10320%0.198CC..EExtended strand (participates in β ladder)trans-178.3-165.7178.400000112.8L43 N136L43-G528 CarbonylContact O-C 3.57Å; L43-G528 WeakPolarHBondContact O-CA 3.47Å; N136-G528 PolarHBondContact OD1-N 3.08Å
529M97.8Very high96.7Very high36 Ų3641.3 Ų41.318%0.17721%0.211CC..EExtended strand (participates in β ladder)trans-146.2158.2179.666.7173.9-63.700111.3L43 V137 P139 F144 K531L43-M529 HydrophobicContact CB-CG 4.43Å; L43-M529 HydrophobicContact CD1-CG 4.3Å; L43-M529 PolarHBondContact N-O 3Å; L43-M529 PolarHBondContact O-N 2.71Å; V137-M529 HydrophobicContact CG1-CG 4.35Å; P139-M529 HydrophobicContact CG-CE 4.29Å; F144-M529 HydrophobicContact CD1-CE 4.45Å; F144-M529 HydrophobicContact CD1-SD 3.76Å; F144-M529 HydrophobicContact CE1-CE 3.78Å; F144-M529 HydrophobicContact CE1-SD 3.69Å; M529-K531 HydrophobicContact CE-CB 4.43Å
530Y97.9Very high96.8Very high34 Ų3432.5 Ų32.513%0.13317%0.171CC..EExtended strand (participates in β ladder)trans-99118164.4-173.2-108000109.4L38 K39 L42 F72 V474 L488 Q532L38-Y530 WeakPolarHBondContact CA-OH 3.17Å; L38-Y530 HydrophobicContact CD2-CE1 4.48Å; K39-Y530 PolarHBondContact N-OH 3.15Å; K39-Y530 PolarHBondContact O-OH 2.81Å; L42-Y530 HydrophobicContact CB-CD2 4.37Å; F72-Y530 AromaticContact CD2-CE2 3.94Å; F72-Y530 HydrophobicContact CD2-CE2 3.94Å; F72-Y530 HydrophobicContact CE2-CE2 4.13Å; V474-Y530 HydrophobicContact CB-CD1 4.38Å; V474-Y530 HydrophobicContact CG1-CD1 3.81Å; V474-Y530 HydrophobicContact CG1-CE1 3.72Å; V474-Y530 HydrophobicContact CG2-CD1 3.59Å; V474-Y530 HydrophobicContact CG2-CD2 4.17Å; V474-Y530 HydrophobicContact CG2-CE1 4.11Å; V474-Y530 HydrophobicContact CG2-CG 3.61Å; L488-Y530 HydrophobicContact CD1-CD2 3.51Å; L488-Y530 HydrophobicContact CD1-CE2 3.76Å; L488-Y530 HydrophobicContact CD1-CG 4.24Å; Y530-Q532 HydrophobicContact CD1-CG 4.04Å; Y530-Q532 HydrophobicContact CE1-CG 3.6Å
531K96.1Very high97Very high48 Ų4833.3 Ų33.321%0.20917%0.173CC..EExtended strand (participates in β ladder)trans-95.9107.8174.1177.2-170.2173.1-169.50107.8G40 S41 L43 F144 T158 D159 M529G40-K531 CarbonylContact C-O 3.56Å; G40-K531 WeakPolarHBondContact CA-O 3.49Å; S41-K531 PolarHBondContact N-O 3.21Å; S41-K531 PolarHBondContact O-N 3.45Å; L43-K531 HydrophobicContact CD1-CB 4.43Å; F144-K531 HydrophobicContact CE1-CD 4.42Å; F144-K531 HydrophobicContact CE2-CD 4.45Å; F144-K531 HydrophobicContact CZ-CD 3.91Å; F144-K531 HydrophobicContact CZ-CG 4.2Å; T158-K531 PolarHBondContact OG1-NZ 3.03Å; D159-K531 IonicContact OD1-NZ 3.23Å; D159-K531 PolarHBondContact OD1-NZ 3.44Å; D159-K531 IonicContact OD2-NZ 3.34Å; M529-K531 HydrophobicContact CE-CB 4.43Å
532Q89.8Confident97.2Very high164 Ų16431.4 Ų31.477%0.76615%0.154SC*.  trans-65.10172.3-90.6-178.34.100112.2Y530Y530-Q532 HydrophobicContact CD1-CG 4.04Å; Y530-Q532 HydrophobicContact CE1-CG 3.6Å

Retrieved 532 of 532 residues in 1056.6 ms (Link to these results)