A0A087YA76_POEFO Loading...

Archaemetzincin-2

Probable zinc metalloprotease.

AlphaFold DB , UniProt , Accession A0A087YA76, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 363 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M79.8Confident93.2Very high165 Ų16582.1 Ų82.181%0.81342%0.418SS*.  0119.60-173.4-175.3-91.600107.6T54 L55 H56M1-T54 HydrophobicContact CE-CG2 3.92Å; M1-T54 HydrophobicContact CG-CG2 3.29Å; M1-T54 HydrophobicContact SD-CG2 3.57Å; M1-T54 VanDerWaalsContact SD-CG2 3.57Å; M1-L55 CarbonylContact C-O 3.52Å; M1-L55 WeakPolarHBondContact CA-O 3.26Å; M1-H56 WeakPolarHBondContact CE-CE1 3.48Å
2N91.1Very high93.5Very high106 Ų10683.3 Ų83.357%0.56741%0.413SS*.EExtended strand (participates in β ladder)trans-119.7142.6-179.5-175.614.2000108.7L55N2-L55 HydrophobicContact CB-CB 4.34Å; N2-L55 PolarHBondContact N-O 2.8Å; N2-L55 WeakPolarHBondContact O-CB 3.36Å; N2-L55 PolarHBondContact O-N 3.43Å
3V93.3Very high93.8Very high56 Ų5678.8 Ų78.834%0.33940%0.395SS..EExtended strand (participates in β ladder)trans-111123.2-179.1-177.90000109Q5 P52 I53V3-Q5 HydrophobicContact CG1-CG 4.29Å; V3-Q5 VanDerWaalsContact CG1-NE2 3.31Å; V3-Q5 PolarHBondContact O-N 2.98Å; V3-P52 HydrophobicContact CG1-CB 3.6Å; V3-P52 HydrophobicContact CG1-CG 3.46Å; V3-P52 VanDerWaalsContact CG1-CG 3.46Å; V3-I53 CarbonylContact C-O 3.58Å; V3-I53 WeakPolarHBondContact CA-O 3.4Å
4V92.6Very high94.1Very high37 Ų3773.4 Ų73.422%0.22437%0.368CS..EExtended strand (participates in β ladder)trans-78.1116175.4-173.20000108.5I53 L55V4-I53 HydrophobicContact CB-CB 4.03Å; V4-I53 HydrophobicContact CG2-CB 4.11Å; V4-I53 HydrophobicContact CG2-CG2 4.47Å; V4-I53 PolarHBondContact N-O 2.76Å; V4-L55 HydrophobicContact CG2-CD1 3.75Å; V4-L55 HydrophobicContact CG2-CD2 4.49Å; V4-L55 HydrophobicContact CG2-CG 3.97Å
5Q89.4Confident94.4Very high120 Ų12068.7 Ų68.756%0.56135%0.345SS*.  trans-111.5136.4179-68.5-69.6-24.500109.9V3V3-Q5 HydrophobicContact CG1-CG 4.29Å; V3-Q5 VanDerWaalsContact CG1-NE2 3.31Å; V3-Q5 PolarHBondContact O-N 2.98Å
6H94.6Very high94.6Very high31 Ų3165.9 Ų65.914%0.14433%0.333CS..  trans-118.4147171.5-62.5-82.3000108.6K10 L11 Q268 W269H6-K10 HydrophobicContact CB-CD 4.33Å; H6-K10 PolarHBondContact ND1-NZ 3.01Å; H6-K10 VanDerWaalsContact ND1-NZ 3.15Å; H6-L11 HydrophobicContact CB-CD1 4.29Å; H6-L11 HydrophobicContact CB-CD2 3.86Å; H6-L11 HydrophobicContact CB-CG 3.82Å; H6-Q268 PolarHBondContact NE2-O 2.85Å; H6-W269 PolarHBondContact CD2-O 3.34Å
7S95.9Very high94.5Very high70 Ų7062.6 Ų62.649%0.4932%0.317SS..  trans-66.8152.8174.965.30000110.9E9 K10 L11S7-E9 PolarHBondContact O-N 3.19Å; S7-K10 PolarHBondContact O-N 2.98Å; S7-K10 WeakPolarHBondContact OG-CB 3.3Å; S7-K10 PolarHBondContact OG-N 3.31Å; S7-L11 PolarHBondContact O-N 3.27Å
8E96.4Very high94.4Very high87 Ų8767.1 Ų67.141%0.40733%0.334SS..Hα-helixtrans-54-43.2174.6176.4173.7168.600111.7K10 L11 R12 L41 H42E8-K10 VanDerWaalsContact C-N 3.31Å; E8-K10 PolarHBondContact O-N 3.11Å; E8-L11 PolarHBondContact O-N 2.93Å; E8-R12 VanDerWaalsContact O-CB 3.3Å; E8-R12 WeakPolarHBondContact O-CB 3.1Å; E8-R12 PolarHBondContact O-N 3.44Å; E8-R12 IonicContact OE1-NH2 2.8Å; E8-L41 HydrophobicContact CG-CB 4.25Å; E8-H42 IonicContact OE1-CE1 2.79Å; E8-H42 IonicContact OE1-NE2 3.88Å; E8-H42 IonicContact OE2-CD2 3.54Å; E8-H42 IonicContact OE2-CE1 3.64Å; E8-H42 IonicContact OE2-NE2 3.96Å; E8-H42 PolarHBondContact OE2-NE2 3.26Å
9E96.9Very high94.3Very high135 Ų13566.8 Ų66.863%0.63133%0.333SS*.Hα-helixtrans-59.6-41.8177.6-169.9-164.715500111.8S7 S13 K18S7-E9 PolarHBondContact O-N 3.19Å; E9-S13 WeakPolarHBondContact O-CB 3.45Å; E9-S13 PolarHBondContact O-N 3.48Å; E9-S13 PolarHBondContact O-OG 2.9Å; E9-K18 IonicContact OE1-NZ 3.78Å
10K97.1Very high94.2Very high95 Ų9569 Ų6941%0.41335%0.352SS..Hα-helixtrans-68.2-43.4179.4-165.7-174.4179.1-169.40110.9H6 S7 E8 S13 A14 W269H6-K10 HydrophobicContact CB-CD 4.33Å; H6-K10 PolarHBondContact ND1-NZ 3.01Å; H6-K10 VanDerWaalsContact ND1-NZ 3.15Å; S7-K10 PolarHBondContact O-N 2.98Å; S7-K10 WeakPolarHBondContact OG-CB 3.3Å; S7-K10 PolarHBondContact OG-N 3.31Å; E8-K10 VanDerWaalsContact C-N 3.31Å; E8-K10 PolarHBondContact O-N 3.11Å; K10-S13 PolarHBondContact O-N 3.49Å; K10-A14 WeakPolarHBondContact O-CB 3.44Å; K10-A14 PolarHBondContact O-N 3.17Å; K10-W269 HydrophobicContact CD-CZ3 4.05Å; K10-W269 HydrophobicContact CG-CH2 4.33Å; K10-W269 HydrophobicContact CG-CZ3 3.91Å
11L97.7Very high94Very high1 Ų169.9 Ų69.91%0.00537%0.37CS..Hα-helixtrans-64.3-41.6176.1-68.9171.9000111.9H6 S7 E8 A14 L15 L41 P43 W269 M270 I293H6-L11 HydrophobicContact CB-CD1 4.29Å; H6-L11 HydrophobicContact CB-CD2 3.86Å; H6-L11 HydrophobicContact CB-CG 3.82Å; S7-L11 PolarHBondContact O-N 3.27Å; E8-L11 PolarHBondContact O-N 2.93Å; L11-A14 PolarHBondContact O-N 3.02Å; L11-L15 WeakPolarHBondContact O-CB 3.49Å; L11-L15 PolarHBondContact O-N 2.98Å; L11-L41 HydrophobicContact CB-CD2 3.8Å; L11-P43 HydrophobicContact CD1-CG 4.15Å; L11-W269 HydrophobicContact CD2-CE3 4.14Å; L11-M270 HydrophobicContact CD2-CE 3.82Å; L11-I293 HydrophobicContact CD2-CD1 4.39Å
12R97.7Very high94.6Very high96 Ų9662.4 Ų62.436%0.36233%0.334SS..Hα-helixtrans-63.3-44.1176.4-176.7175.7-68.1-794.2111.4E8 A14 L15 V16 E38 L41E8-R12 VanDerWaalsContact O-CB 3.3Å; E8-R12 WeakPolarHBondContact O-CB 3.1Å; E8-R12 PolarHBondContact O-N 3.44Å; E8-R12 IonicContact OE1-NH2 2.8Å; R12-A14 VanDerWaalsContact C-N 3.3Å; R12-A14 PolarHBondContact O-N 3.3Å; R12-L15 PolarHBondContact O-N 3.25Å; R12-V16 PolarHBondContact O-N 2.85Å; R12-E38 IonicContact CZ-OE1 3.45Å; R12-E38 IonicContact NH1-OE1 2.68Å; R12-E38 PolarHBondContact NH1-OE1 3.23Å; R12-E38 IonicContact NH2-OE1 3.71Å; R12-L41 HydrophobicContact CB-CD1 4.47Å; R12-L41 HydrophobicContact CB-CD2 3.92Å; R12-L41 VanDerWaalsContact CZ-CD1 3.44Å
13S97.3Very high94.7Very high26 Ų2658.4 Ų58.418%0.18232%0.315CS..Hα-helixtrans-62.3-40.6175.2-570000111.4E9 K10 L15 S17 K18E9-S13 WeakPolarHBondContact O-CB 3.45Å; E9-S13 PolarHBondContact O-N 3.48Å; E9-S13 PolarHBondContact O-OG 2.9Å; K10-S13 PolarHBondContact O-N 3.49Å; S13-L15 VanDerWaalsContact C-N 3.35Å; S13-S17 WeakPolarHBondContact O-CA 3.35Å; S13-S17 PolarHBondContact O-N 3.14Å; S13-K18 WeakPolarHBondContact OG-CE 3.47Å
14A98.1Very high94.8Very high2 Ų262.6 Ų62.62%0.01733%0.329CS..Hα-helixtrans-69.8-31.8-179.900000113.4K10 L11 R12 D71 F72 W269 I293K10-A14 WeakPolarHBondContact O-CB 3.44Å; K10-A14 PolarHBondContact O-N 3.17Å; L11-A14 PolarHBondContact O-N 3.02Å; R12-A14 VanDerWaalsContact C-N 3.3Å; R12-A14 PolarHBondContact O-N 3.3Å; A14-D71 HydrophobicContact CB-CB 3.84Å; A14-F72 WeakPolarHBondContact O-CB 3.25Å; A14-F72 PolarHBondContact O-N 3.45Å; A14-W269 HydrophobicContact CB-CD2 3.97Å; A14-W269 HydrophobicContact CB-CE3 4.02Å; A14-W269 HydrophobicContact CB-CH2 3.58Å; A14-W269 HydrophobicContact CB-CZ2 3.53Å; A14-W269 HydrophobicContact CB-CZ3 3.83Å; A14-I293 HydrophobicContact CB-CD1 3.74Å; A14-I293 HydrophobicContact CB-CG1 4.49Å
15L98.1Very high94.8Very high3 Ų362.9 Ų62.92%0.01633%0.329CS..Hα-helixtrans-79.3-47177.7178.761.6000112.3L11 R12 S13 Y26 L37 L41 P292 I293 H296L11-L15 WeakPolarHBondContact O-CB 3.49Å; L11-L15 PolarHBondContact O-N 2.98Å; R12-L15 PolarHBondContact O-N 3.25Å; S13-L15 VanDerWaalsContact C-N 3.35Å; L15-Y26 HydrophobicContact CD1-CE2 4.08Å; L15-Y26 HydrophobicContact CD2-CE2 3.93Å; L15-Y26 HydrophobicContact CG-CD2 4.42Å; L15-Y26 HydrophobicContact CG-CE2 3.74Å; L15-L37 HydrophobicContact CD2-CB 4.16Å; L15-L41 HydrophobicContact CD2-CD2 4.45Å; L15-P292 HydrophobicContact CD1-CB 4.27Å; L15-I293 HydrophobicContact CB-CG1 4.07Å; L15-I293 HydrophobicContact CD1-CG1 4.26Å; L15-H296 HydrophobicContact CD1-CB 3.97Å; L15-H296 PolarHBondContact O-CD2 2.96Å
16V96.9Very high95.1Very high25 Ų2557.8 Ų57.815%0.15231%0.305CS..Hα-helixtrans-100.3-22.3-167.6-178.10000113.5R12 A23 Y26R12-V16 PolarHBondContact O-N 2.85Å; V16-A23 HydrophobicContact CG1-CB 3.87Å; V16-A23 VanDerWaalsContact O-CA 3.24Å; V16-A23 WeakPolarHBondContact O-CA 3.42Å; V16-Y26 HydrophobicContact CB-CG 4.42Å; V16-Y26 HydrophobicContact CG1-CD1 4.2Å; V16-Y26 HydrophobicContact CG1-CG 4.12Å; V16-Y26 HydrophobicContact CG2-CD1 3.8Å; V16-Y26 HydrophobicContact CG2-CD2 4.02Å; V16-Y26 HydrophobicContact CG2-CE1 3.9Å; V16-Y26 HydrophobicContact CG2-CE2 4.12Å; V16-Y26 HydrophobicContact CG2-CG 3.87Å
17S94.5Very high94.9Very high9 Ų959.7 Ų59.76%0.06332%0.322CS..  trans72.6147.8-162175.40000113.8S13 L19 E73S13-S17 WeakPolarHBondContact O-CA 3.35Å; S13-S17 PolarHBondContact O-N 3.14Å; S17-L19 PolarHBondContact OG-N 3.12Å; S17-E73 PolarHBondContact OG-OE2 3.49Å
18K91.2Very high94.8Very high143 Ų14362.3 Ų62.362%0.62233%0.33SS*.SBendtrans-87.1-14.2170.9-65.6-172.7178.2-169.70112.4E9 S13 P20E9-K18 IonicContact OE1-NZ 3.78Å; S13-K18 WeakPolarHBondContact OG-CE 3.47Å; K18-P20 WeakPolarHBondContact O-CD 3.33Å
19L93.1Very high94.7Very high63 Ų6358.7 Ų58.733%0.3331%0.313SS..SBendtrans-81.7119.2178.3-67.5-178.4000110.4S17 A21 V22 A23 E73S17-L19 PolarHBondContact OG-N 3.12Å; L19-A21 PolarHBondContact O-N 3.32Å; L19-A21 VanDerWaalsContact O-N 3.11Å; L19-V22 HydrophobicContact CB-CB 4.41Å; L19-V22 HydrophobicContact CB-CG2 4.24Å; L19-V22 PolarHBondContact O-N 2.75Å; L19-A23 PolarHBondContact O-N 2.56Å; L19-E73 VanDerWaalsContact CD1-CD 3.42Å; L19-E73 HydrophobicContact CD1-CG 4.06Å; L19-E73 WeakPolarHBondContact CD1-OE1 3.17Å; L19-E73 WeakPolarHBondContact CG-OE1 3.24Å; L19-E73 WeakPolarHBondContact CG-OE2 3.48Å
20P91.9Very high94.7Very high110 Ų11056.1 Ų56.171%0.71431%0.307SS*.Hα-helixtrans-55.9-35.3-175.2-28.635.6000114.6K18 V22 K24K18-P20 WeakPolarHBondContact O-CD 3.33Å; P20-V22 VanDerWaalsContact C-N 3.31Å; P20-V22 PolarHBondContact O-N 3.42Å; P20-K24 PolarHBondContact O-N 2.94Å
21A91.3Very high94.5Very high88 Ų8857.2 Ų57.273%0.72731%0.313SS*.Hα-helixtrans-65.1-33.617900000113L19L19-A21 PolarHBondContact O-N 3.32Å; L19-A21 VanDerWaalsContact O-N 3.11Å
22V92.2Very high94.4Very high8 Ų857.5 Ų57.55%0.04832%0.316CS..Hα-helixtrans-85.4-42179179.90000110.1L19 P20 K24 L25 F72 Y76L19-V22 HydrophobicContact CB-CB 4.41Å; L19-V22 HydrophobicContact CB-CG2 4.24Å; L19-V22 PolarHBondContact O-N 2.75Å; P20-V22 VanDerWaalsContact C-N 3.31Å; P20-V22 PolarHBondContact O-N 3.42Å; V22-K24 PolarHBondContact O-N 3.19Å; V22-K24 VanDerWaalsContact O-N 3.12Å; V22-L25 WeakPolarHBondContact O-CB 3.38Å; V22-L25 WeakPolarHBondContact O-CG 3.36Å; V22-L25 PolarHBondContact O-N 3.41Å; V22-F72 HydrophobicContact CG1-CD1 3.73Å; V22-F72 HydrophobicContact CG1-CE1 3.45Å; V22-F72 VanDerWaalsContact CG1-CE1 3.45Å; V22-F72 HydrophobicContact CG1-CZ 4.5Å; V22-Y76 HydrophobicContact CG1-CD1 4.37Å; V22-Y76 HydrophobicContact CG1-CG 4.48Å; V22-Y76 HydrophobicContact CG2-CD1 4.19Å
23A93.6Very high94.3Very high21 Ų2153.9 Ų53.917%0.17430%0.303CS..Hα-helixtrans-58.9-24.5177.400000113.9V16 L19 L25 Y26V16-A23 HydrophobicContact CG1-CB 3.87Å; V16-A23 VanDerWaalsContact O-CA 3.24Å; V16-A23 WeakPolarHBondContact O-CA 3.42Å; L19-A23 PolarHBondContact O-N 2.56Å; A23-L25 PolarHBondContact O-N 3.23Å; A23-Y26 WeakPolarHBondContact O-CB 3.24Å; A23-Y26 PolarHBondContact O-N 3.36Å; A23-Y26 VanDerWaalsContact O-N 3.14Å
24K93.9Very high94.3Very high144 Ų14457 Ų5763%0.62631%0.311SS*.Hα-helixtrans-57.6-35.6173.4-170.8179.2177.5-173.50112.4P20 V22 Y26 S27P20-K24 PolarHBondContact O-N 2.94Å; V22-K24 PolarHBondContact O-N 3.19Å; V22-K24 VanDerWaalsContact O-N 3.12Å; K24-Y26 PolarHBondContact O-N 2.99Å; K24-S27 WeakPolarHBondContact O-CA 3.42Å; K24-S27 VanDerWaalsContact O-CB 3.24Å; K24-S27 WeakPolarHBondContact O-CB 3.35Å; K24-S27 PolarHBondContact O-N 2.75Å
25L93.8Very high94.1Very high43 Ų4360.3 Ų60.323%0.22532%0.323CS..Hα-helixtrans-61.5-32.4178.6-62.1168.1000112.2V22 A23 S27 F72 Y76 V300V22-L25 WeakPolarHBondContact O-CB 3.38Å; V22-L25 WeakPolarHBondContact O-CG 3.36Å; V22-L25 PolarHBondContact O-N 3.41Å; A23-L25 PolarHBondContact O-N 3.23Å; L25-S27 VanDerWaalsContact C-N 3.27Å; L25-S27 PolarHBondContact O-N 3.02Å; L25-F72 HydrophobicContact CB-CZ 4.48Å; L25-F72 HydrophobicContact CD1-CE1 4.12Å; L25-F72 HydrophobicContact CD1-CZ 3.9Å; L25-Y76 HydrophobicContact CD1-CD1 4.45Å; L25-Y76 HydrophobicContact CD1-CD2 3.74Å; L25-Y76 HydrophobicContact CD1-CE1 4.1Å; L25-Y76 HydrophobicContact CD1-CE2 3.33Å; L25-Y76 HydrophobicContact CD1-CG 4.29Å; L25-V300 HydrophobicContact CD1-CG1 4.35Å
26Y94.7Very high94Very high13 Ų1360.1 Ų60.15%0.05132%0.322CS..Hα-helixtrans-72.9-22.8175.4-167.6-94.2000112.5L15 V16 A23 K24 D28 Y29 R34 L37 E38 H296L15-Y26 HydrophobicContact CD1-CE2 4.08Å; L15-Y26 HydrophobicContact CD2-CE2 3.93Å; L15-Y26 HydrophobicContact CG-CD2 4.42Å; L15-Y26 HydrophobicContact CG-CE2 3.74Å; V16-Y26 HydrophobicContact CB-CG 4.42Å; V16-Y26 HydrophobicContact CG1-CD1 4.2Å; V16-Y26 HydrophobicContact CG1-CG 4.12Å; V16-Y26 HydrophobicContact CG2-CD1 3.8Å; V16-Y26 HydrophobicContact CG2-CD2 4.02Å; V16-Y26 HydrophobicContact CG2-CE1 3.9Å; V16-Y26 HydrophobicContact CG2-CE2 4.12Å; V16-Y26 HydrophobicContact CG2-CG 3.87Å; A23-Y26 WeakPolarHBondContact O-CB 3.24Å; A23-Y26 PolarHBondContact O-N 3.36Å; A23-Y26 VanDerWaalsContact O-N 3.14Å; K24-Y26 PolarHBondContact O-N 2.99Å; Y26-D28 PolarHBondContact O-N 3.06Å; Y26-Y29 AromaticContact CD2-CD2 3.84Å; Y26-Y29 HydrophobicContact CD2-CD2 3.84Å; Y26-Y29 AromaticContact CD2-CE2 3.85Å; Y26-Y29 HydrophobicContact CD2-CE2 3.85Å; Y26-Y29 HydrophobicContact CE2-CD2 4.07Å; Y26-Y29 HydrophobicContact CE2-CE2 4.16Å; Y26-Y29 HydrophobicContact CG-CD2 4.21Å; Y26-Y29 WeakPolarHBondContact O-CD2 3.34Å; Y26-Y29 PolarHBondContact O-N 2.81Å; Y26-R34 HydrophobicContact CD1-CG 4.41Å; Y26-R34 HydrophobicContact CE1-CB 4.38Å; Y26-R34 HydrophobicContact CE1-CG 3.8Å; Y26-L37 HydrophobicContact CE2-CB 4.27Å; Y26-L37 HydrophobicContact CE2-CD1 3.7Å; Y26-L37 WeakPolarHBondContact OH-CB 3.37Å; Y26-E38 WeakPolarHBondContact OH-CG 2.92Å; Y26-H296 AromaticContact CD2-NE2 3.92Å
27S91Very high94Very high72 Ų7259 Ų5950%0.50332%0.315SS..Hα-helixtrans-74.8-17.3179.4-55.50000112.9K24 L25 Y29K24-S27 WeakPolarHBondContact O-CA 3.42Å; K24-S27 VanDerWaalsContact O-CB 3.24Å; K24-S27 WeakPolarHBondContact O-CB 3.35Å; K24-S27 PolarHBondContact O-N 2.75Å; L25-S27 VanDerWaalsContact C-N 3.27Å; L25-S27 PolarHBondContact O-N 3.02Å; S27-Y29 VanDerWaalsContact C-N 3.26Å; S27-Y29 PolarHBondContact O-N 2.85Å
28D92.6Very high94Very high124 Ų12461.5 Ų61.566%0.66333%0.326SS*.THydrogen-bonded Turntrans-76.3-14.4178.5-64.1-22.9000112.5Y26Y26-D28 PolarHBondContact O-N 3.06Å
29Y96Very high94.1Very high11 Ų1156.8 Ų56.84%0.04331%0.306CS..SBendtrans-67143.6173.8-76.1-55.6000112.3Y26 S27 E33 R34 L37 H296 Q299 I306Y26-Y29 AromaticContact CD2-CD2 3.84Å; Y26-Y29 HydrophobicContact CD2-CD2 3.84Å; Y26-Y29 AromaticContact CD2-CE2 3.85Å; Y26-Y29 HydrophobicContact CD2-CE2 3.85Å; Y26-Y29 HydrophobicContact CE2-CD2 4.07Å; Y26-Y29 HydrophobicContact CE2-CE2 4.16Å; Y26-Y29 HydrophobicContact CG-CD2 4.21Å; Y26-Y29 WeakPolarHBondContact O-CD2 3.34Å; Y26-Y29 PolarHBondContact O-N 2.81Å; S27-Y29 VanDerWaalsContact C-N 3.26Å; S27-Y29 PolarHBondContact O-N 2.85Å; Y29-E33 HydrophobicContact CD1-CB 3.77Å; Y29-E33 HydrophobicContact CD1-CG 4.31Å; Y29-E33 HydrophobicContact CG-CB 4.11Å; Y29-R34 HydrophobicContact CG-CG 4.47Å; Y29-L37 HydrophobicContact CD2-CD1 3.69Å; Y29-L37 HydrophobicContact CE1-CD1 4.34Å; Y29-L37 HydrophobicContact CE2-CD1 3.4Å; Y29-L37 VanDerWaalsContact CE2-CD1 3.4Å; Y29-L37 HydrophobicContact CG-CD1 4.26Å; Y29-H296 AromaticContact CE2-CE1 3.55Å; Y29-H296 AromaticContact CE2-ND1 3.25Å; Y29-H296 VanDerWaalsContact CE2-ND1 3.25Å; Y29-H296 WeakPolarHBondContact CE2-ND1 3.19Å; Y29-H296 AromaticContact CZ-ND1 3.47Å; Y29-H296 PolarHBondContact OH-ND1 3.12Å; Y29-Q299 HydrophobicContact CE1-CG 4.01Å; Y29-Q299 VanDerWaalsContact CE1-OE1 3.27Å; Y29-Q299 VanDerWaalsContact CZ-OE1 3.23Å; Y29-Q299 PolarHBondContact OH-OE1 2.89Å; Y29-I306 HydrophobicContact CE1-CD1 4.06Å
30T95.4Very high94.2Very high82 Ų8254 Ų5450%0.50329%0.292SS..  trans-60.6162.8167.9620000111.2G32 E33 R34T30-G32 VanDerWaalsContact C-N 3.3Å; T30-G32 PolarHBondContact O-N 2.69Å; T30-E33 WeakPolarHBondContact CG2-OE2 3.34Å; T30-E33 PolarHBondContact N-OE2 3.39Å; T30-E33 PolarHBondContact O-N 3.47Å; T30-E33 WeakPolarHBondContact OG1-CB 3.49Å; T30-E33 VanDerWaalsContact OG1-CG 3.25Å; T30-E33 WeakPolarHBondContact OG1-CG 3.12Å; T30-E33 PolarHBondContact OG1-N 3.48Å; T30-E33 PolarHBondContact OG1-OE2 2.94Å; T30-R34 WeakPolarHBondContact O-CG 3.3Å; T30-R34 PolarHBondContact O-N 3.49Å
31E94.1Very high94.3Very high118 Ų11849 Ų4955%0.55126%0.259SS*.Hα-helixtrans-58.9-42.4175.5-163.8-176.4151.500112.1R34 R35E31-R34 PolarHBondContact O-N 3.14Å; E31-R35 WeakPolarHBondContact O-CG 3.43Å; E31-R35 PolarHBondContact O-N 3.4Å; E31-R35 IonicContact OE1-CZ 3.72Å; E31-R35 IonicContact OE1-NH1 3.8Å; E31-R35 PolarHBondContact OE1-NH1 2.92Å; E31-R35 IonicContact OE2-NH1 3.73Å
32G94.9Very high94.4Very high6 Ų647.6 Ų47.66%0.06224%0.238CC..Hα-helixtrans-60.1-45.717600000113.2T30 R35 L36T30-G32 VanDerWaalsContact C-N 3.3Å; T30-G32 PolarHBondContact O-N 2.69Å; G32-R35 VanDerWaalsContact CA-NH2 3.32Å; G32-R35 PolarHBondContact O-N 2.81Å; G32-L36 PolarHBondContact O-N 2.9Å
33E96.6Very high94.5Very high21 Ų2147.9 Ų47.910%0.09824%0.24CC..Hα-helixtrans-64.1-42.5177-73168.2135.800112Y29 T30 L36 L37 I306 L360Y29-E33 HydrophobicContact CD1-CB 3.77Å; Y29-E33 HydrophobicContact CD1-CG 4.31Å; Y29-E33 HydrophobicContact CG-CB 4.11Å; T30-E33 WeakPolarHBondContact CG2-OE2 3.34Å; T30-E33 PolarHBondContact N-OE2 3.39Å; T30-E33 PolarHBondContact O-N 3.47Å; T30-E33 WeakPolarHBondContact OG1-CB 3.49Å; T30-E33 VanDerWaalsContact OG1-CG 3.25Å; T30-E33 WeakPolarHBondContact OG1-CG 3.12Å; T30-E33 PolarHBondContact OG1-N 3.48Å; T30-E33 PolarHBondContact OG1-OE2 2.94Å; E33-L36 PolarHBondContact O-N 3.48Å; E33-L37 VanDerWaalsContact O-CG 3.29Å; E33-L37 WeakPolarHBondContact O-CG 3.45Å; E33-L37 PolarHBondContact O-N 3.2Å; E33-I306 HydrophobicContact CB-CD1 4.34Å; E33-I306 HydrophobicContact CG-CB 4.41Å; E33-I306 HydrophobicContact CG-CD1 4.18Å; E33-I306 PolarHBondContact OE1-N 3.13Å; E33-L360 HydrophobicContact CB-CD2 4.41Å; E33-L360 HydrophobicContact CG-CD2 3.86Å
34R95.8Very high94.3Very high91 Ų9148.8 Ų48.834%0.34325%0.251SS..Hα-helixtrans-62.5-45.2175.5-70.6-172.8-67.8-167.70.2111.6Y26 Y29 T30 E31 L36 L37 E38Y26-R34 HydrophobicContact CD1-CG 4.41Å; Y26-R34 HydrophobicContact CE1-CB 4.38Å; Y26-R34 HydrophobicContact CE1-CG 3.8Å; Y29-R34 HydrophobicContact CG-CG 4.47Å; T30-R34 WeakPolarHBondContact O-CG 3.3Å; T30-R34 PolarHBondContact O-N 3.49Å; E31-R34 PolarHBondContact O-N 3.14Å; R34-L36 VanDerWaalsContact C-N 3.33Å; R34-L36 PolarHBondContact O-N 3.07Å; R34-L37 PolarHBondContact O-N 2.97Å; R34-E38 WeakPolarHBondContact O-CB 3.26Å; R34-E38 VanDerWaalsContact O-CG 3.28Å; R34-E38 WeakPolarHBondContact O-CG 3.43Å; R34-E38 PolarHBondContact O-N 3.13Å
35R94.3Very high94.1Very high71 Ų7147.6 Ų47.627%0.26825%0.246SC..Hα-helixtrans-58.6-44.5176.8-73.9-176.9-55.6-125.5-0.8111.7E31 G32 E38 E39 I362 S363E31-R35 WeakPolarHBondContact O-CG 3.43Å; E31-R35 PolarHBondContact O-N 3.4Å; E31-R35 IonicContact OE1-CZ 3.72Å; E31-R35 IonicContact OE1-NH1 3.8Å; E31-R35 PolarHBondContact OE1-NH1 2.92Å; E31-R35 IonicContact OE2-NH1 3.73Å; G32-R35 VanDerWaalsContact CA-NH2 3.32Å; G32-R35 PolarHBondContact O-N 2.81Å; R35-E38 PolarHBondContact O-N 3.37Å; R35-E39 PolarHBondContact O-N 2.92Å; R35-I362 PolarHBondContact NH2-O 2.97Å; R35-S363 PolarHBondContact NH1-OXT 3.36Å; R35-S363 PolarHBondContact NH2-OXT 3.23Å
36L95.8Very high93.6Very high0 Ų058 Ų580%028%0.282CS..Hα-helixtrans-60.2-47.217517674.8000111.6G32 E33 R34 E38 E39 L49 I306 Y310 C356 R359 L360G32-L36 PolarHBondContact O-N 2.9Å; E33-L36 PolarHBondContact O-N 3.48Å; R34-L36 VanDerWaalsContact C-N 3.33Å; R34-L36 PolarHBondContact O-N 3.07Å; L36-E38 VanDerWaalsContact C-N 3.32Å; L36-E38 PolarHBondContact O-N 2.91Å; L36-E39 WeakPolarHBondContact O-CB 3.48Å; L36-E39 PolarHBondContact O-N 3.36Å; L36-L49 HydrophobicContact CD1-CD1 3.61Å; L36-I306 HydrophobicContact CD2-CG2 3.8Å; L36-Y310 HydrophobicContact CD2-CE2 3.67Å; L36-C356 HydrophobicContact CD1-CB 4.02Å; L36-R359 HydrophobicContact CD1-CB 4.35Å; L36-L360 HydrophobicContact CB-CD2 3.96Å; L36-L360 HydrophobicContact CB-CG 4.42Å; L36-L360 HydrophobicContact CD2-CD1 4Å; L36-L360 HydrophobicContact CD2-CD2 3.75Å; L36-L360 HydrophobicContact CD2-CG 3.91Å; L36-L360 HydrophobicContact CG-CD2 4.45Å
37L96.9Very high92.9Very high0 Ų060.1 Ų60.10%031%0.308CS..Hα-helixtrans-66.3-36.5-178.9-68.1171.5000111.7L15 Y26 Y29 E33 R34 E39 G40 P292 L295 I306L15-L37 HydrophobicContact CD2-CB 4.16Å; Y26-L37 HydrophobicContact CE2-CB 4.27Å; Y26-L37 HydrophobicContact CE2-CD1 3.7Å; Y26-L37 WeakPolarHBondContact OH-CB 3.37Å; Y29-L37 HydrophobicContact CD2-CD1 3.69Å; Y29-L37 HydrophobicContact CE1-CD1 4.34Å; Y29-L37 HydrophobicContact CE2-CD1 3.4Å; Y29-L37 VanDerWaalsContact CE2-CD1 3.4Å; Y29-L37 HydrophobicContact CG-CD1 4.26Å; E33-L37 VanDerWaalsContact O-CG 3.29Å; E33-L37 WeakPolarHBondContact O-CG 3.45Å; E33-L37 PolarHBondContact O-N 3.2Å; R34-L37 PolarHBondContact O-N 2.97Å; L37-E39 VanDerWaalsContact C-N 3.31Å; L37-E39 PolarHBondContact O-N 2.8Å; L37-G40 PolarHBondContact O-N 3.47Å; L37-G40 VanDerWaalsContact O-N 3.17Å; L37-P292 HydrophobicContact CB-CB 4.29Å; L37-P292 HydrophobicContact CD2-CB 3.81Å; L37-P292 VanDerWaalsContact O-CB 3.28Å; L37-P292 WeakPolarHBondContact O-CB 3.43Å; L37-L295 HydrophobicContact CD2-CB 4.42Å; L37-L295 HydrophobicContact CD2-CD2 3.92Å; L37-L295 HydrophobicContact CD2-CG 4.29Å; L37-I306 HydrophobicContact CD1-CD1 4.4Å; L37-I306 HydrophobicContact CD2-CD1 4.35Å; L37-I306 HydrophobicContact CG-CD1 4.44Å
38E95.3Very high92.7Very high63 Ų6357.4 Ų57.429%0.29429%0.289SS..Hα-helixtrans-72.6-17.3179.8-71.5-173.1143.600113.9R12 Y26 R34 R35 L36 G40 L41R12-E38 IonicContact CZ-OE1 3.45Å; R12-E38 IonicContact NH1-OE1 2.68Å; R12-E38 PolarHBondContact NH1-OE1 3.23Å; R12-E38 IonicContact NH2-OE1 3.71Å; Y26-E38 WeakPolarHBondContact OH-CG 2.92Å; R34-E38 WeakPolarHBondContact O-CB 3.26Å; R34-E38 VanDerWaalsContact O-CG 3.28Å; R34-E38 WeakPolarHBondContact O-CG 3.43Å; R34-E38 PolarHBondContact O-N 3.13Å; R35-E38 PolarHBondContact O-N 3.37Å; L36-E38 VanDerWaalsContact C-N 3.32Å; L36-E38 PolarHBondContact O-N 2.91Å; E38-G40 PolarHBondContact O-N 3.06Å; E38-G40 VanDerWaalsContact O-N 3.16Å; E38-L41 HydrophobicContact CB-CD1 4.04Å; E38-L41 HydrophobicContact CB-CG 4.42Å; E38-L41 HydrophobicContact CG-CD1 4.01Å; E38-L41 VanDerWaalsContact O-CB 3.22Å; E38-L41 WeakPolarHBondContact O-CB 3.25Å; E38-L41 VanDerWaalsContact O-CG 3.29Å; E38-L41 WeakPolarHBondContact O-CG 3.45Å; E38-L41 PolarHBondContact O-N 2.91Å
39E93.8Very high92.8Very high44 Ų4452.5 Ų52.521%0.20626%0.263CS..G310 helixtrans-55.9-28.6166.7-77-81.4157.300112R35 L36 L37 L41 H42 S48 F50 R359R35-E39 PolarHBondContact O-N 2.92Å; L36-E39 WeakPolarHBondContact O-CB 3.48Å; L36-E39 PolarHBondContact O-N 3.36Å; L37-E39 VanDerWaalsContact C-N 3.31Å; L37-E39 PolarHBondContact O-N 2.8Å; E39-L41 PolarHBondContact O-N 3.4Å; E39-H42 PolarHBondContact O-N 2.94Å; E39-S48 PolarHBondContact O-OG 2.82Å; E39-F50 HydrophobicContact CB-CD2 3.85Å; E39-F50 HydrophobicContact CB-CE2 3.89Å; E39-R359 IonicContact OE1-CZ 3.76Å; E39-R359 IonicContact OE1-NH1 3.62Å; E39-R359 PolarHBondContact OE1-NH1 3.05Å; E39-R359 IonicContact OE1-NH2 2.86Å
40G93.9Very high92.8Very high3 Ų352.3 Ų52.33%0.03126%0.262CS..G310 helixtrans-70.8-8175.300000114.9L37 E38 H42 P43 M270L37-G40 PolarHBondContact O-N 3.47Å; L37-G40 VanDerWaalsContact O-N 3.17Å; E38-G40 PolarHBondContact O-N 3.06Å; E38-G40 VanDerWaalsContact O-N 3.16Å; G40-H42 PolarHBondContact O-N 3.28Å; G40-P43 WeakPolarHBondContact O-CD 3.4Å; G40-M270 VanDerWaalsContact O-CE 3.25Å; G40-M270 WeakPolarHBondContact O-CE 3.48Å
41L95.4Very high92.8Very high6 Ų652.7 Ų52.73%0.03126%0.258CS..G310 helixtrans-76.7-14.3175.4-59.9-177.8000112.5E8 L11 R12 L15 E38 E39 P43E8-L41 HydrophobicContact CG-CB 4.25Å; L11-L41 HydrophobicContact CB-CD2 3.8Å; R12-L41 HydrophobicContact CB-CD1 4.47Å; R12-L41 HydrophobicContact CB-CD2 3.92Å; R12-L41 VanDerWaalsContact CZ-CD1 3.44Å; L15-L41 HydrophobicContact CD2-CD2 4.45Å; E38-L41 HydrophobicContact CB-CD1 4.04Å; E38-L41 HydrophobicContact CB-CG 4.42Å; E38-L41 HydrophobicContact CG-CD1 4.01Å; E38-L41 VanDerWaalsContact O-CB 3.22Å; E38-L41 WeakPolarHBondContact O-CB 3.25Å; E38-L41 VanDerWaalsContact O-CG 3.29Å; E38-L41 WeakPolarHBondContact O-CG 3.45Å; E38-L41 PolarHBondContact O-N 2.91Å; E39-L41 PolarHBondContact O-N 3.4Å; L41-P43 VanDerWaalsContact C-CD 3.49Å
42H93.1Very high92.9Very high58 Ų5847.6 Ų47.627%0.26924%0.235SC..SBendtrans-132.455.1-178-57.1127.2000112.7E8 E39 G40 G44 K45 S48E8-H42 IonicContact OE1-CE1 2.79Å; E8-H42 IonicContact OE1-NE2 3.88Å; E8-H42 IonicContact OE2-CD2 3.54Å; E8-H42 IonicContact OE2-CE1 3.64Å; E8-H42 IonicContact OE2-NE2 3.96Å; E8-H42 PolarHBondContact OE2-NE2 3.26Å; E39-H42 PolarHBondContact O-N 2.94Å; G40-H42 PolarHBondContact O-N 3.28Å; H42-G44 PolarHBondContact O-N 3.17Å; H42-K45 HydrophobicContact CB-CD 3.63Å; H42-K45 HydrophobicContact CB-CG 3.98Å; H42-K45 PolarHBondContact CD2-NZ 3.3Å; H42-K45 PolarHBondContact O-N 3.21Å; H42-S48 PolarHBondContact O-OG 2.8Å
43P92.8Very high92.9Very high15 Ų1547.3 Ų47.310%0.09723%0.232CC..THydrogen-bonded Turntrans-62.8137.6-173.329.2-35.1000111.2L11 G40 L41 K45 F50 P52L11-P43 HydrophobicContact CD1-CG 4.15Å; G40-P43 WeakPolarHBondContact O-CD 3.4Å; L41-P43 VanDerWaalsContact C-CD 3.49Å; P43-K45 VanDerWaalsContact C-N 3.29Å; P43-K45 PolarHBondContact O-N 3.42Å; P43-F50 CarbonylContact C-O 3.49Å; P43-F50 VanDerWaalsContact CA-O 3.28Å; P43-F50 WeakPolarHBondContact CA-O 3.31Å; P43-P52 HydrophobicContact CB-CB 4.45Å
44G90.3Very high92.9Very high39 Ų3948 Ų4840%0.40224%0.239SC..THydrogen-bonded Turntrans80.2-0.117800000115.3H42 F50H42-G44 PolarHBondContact O-N 3.17Å; G44-F50 PolarHBondContact N-O 2.79Å
45K88.8Confident92.8Very high120 Ų12044.5 Ų44.552%0.52223%0.226SC..SBendtrans-64.3149166.7-72.1-165.7-169.3163.70110H42 P43 G47 S48H42-K45 HydrophobicContact CB-CD 3.63Å; H42-K45 HydrophobicContact CB-CG 3.98Å; H42-K45 PolarHBondContact CD2-NZ 3.3Å; H42-K45 PolarHBondContact O-N 3.21Å; P43-K45 VanDerWaalsContact C-N 3.29Å; P43-K45 PolarHBondContact O-N 3.42Å; K45-G47 PolarHBondContact O-N 3.29Å; K45-G47 VanDerWaalsContact O-N 3.17Å; K45-S48 WeakPolarHBondContact O-CB 3.35Å; K45-S48 PolarHBondContact O-N 3.12Å
46R84.2Confident92.8Very high260 Ų26045 Ų4598%0.98123%0.232SC*.THydrogen-bonded Turntrans-56122.7178.5-174.6-179.6-178.6-174.70.3110.1S48R46-S48 VanDerWaalsContact C-N 3.33Å
47G80.7Confident92.6Very high58 Ų5847.1 Ų47.160%0.59825%0.246SC*.THydrogen-bonded Turntrans83.91-178.100000115.2K45 R359K45-G47 PolarHBondContact O-N 3.29Å; K45-G47 VanDerWaalsContact O-N 3.17Å; G47-R359 PolarHBondContact O-NH2 3.15Å
48S86.9Confident92.4Very high16 Ų1653.8 Ų53.811%0.11228%0.282CS..  trans-72.3140.4172-1780000111E39 H42 K45 R46 F50E39-S48 PolarHBondContact O-OG 2.82Å; H42-S48 PolarHBondContact O-OG 2.8Å; K45-S48 WeakPolarHBondContact O-CB 3.35Å; K45-S48 PolarHBondContact O-N 3.12Å; R46-S48 VanDerWaalsContact C-N 3.33Å; S48-F50 VanDerWaalsContact C-N 3.29Å; S48-F50 PolarHBondContact OG-N 3.27Å; S48-F50 PolarHBondContact OG-O 3.37Å
49L93.4Very high92.2Very high20 Ų2053.5 Ų53.511%0.10529%0.287CS..SBendtrans-74.4-19.4176.2-65171.2000113L36 W352 R359L36-L49 HydrophobicContact CD1-CD1 3.61Å; L49-W352 PolarHBondContact O-NE1 2.93Å; L49-R359 HydrophobicContact CD1-CG 3.87Å
50F95.8Very high92.2Very high7 Ų751.5 Ų51.53%0.03128%0.278CS..  trans-116.7142.9-172.4-58.4-76.6000110.9E39 P43 G44 S48 M270 P292 W352E39-F50 HydrophobicContact CB-CD2 3.85Å; E39-F50 HydrophobicContact CB-CE2 3.89Å; P43-F50 CarbonylContact C-O 3.49Å; P43-F50 VanDerWaalsContact CA-O 3.28Å; P43-F50 WeakPolarHBondContact CA-O 3.31Å; G44-F50 PolarHBondContact N-O 2.79Å; S48-F50 VanDerWaalsContact C-N 3.29Å; S48-F50 PolarHBondContact OG-N 3.27Å; S48-F50 PolarHBondContact OG-O 3.37Å; F50-M270 HydrophobicContact CB-SD 4.06Å; F50-M270 HydrophobicContact CG-SD 4.45Å; F50-P292 HydrophobicContact CD1-CG 3.96Å; F50-P292 HydrophobicContact CD2-CG 3.76Å; F50-P292 VanDerWaalsContact CE1-CD 3.44Å; F50-P292 HydrophobicContact CE1-CG 3.63Å; F50-P292 HydrophobicContact CE2-CG 3.45Å; F50-P292 VanDerWaalsContact CE2-CG 3.45Å; F50-P292 HydrophobicContact CG-CG 4.01Å; F50-P292 HydrophobicContact CZ-CG 3.39Å; F50-W352 HydrophobicContact CD1-CZ2 4.37Å; F50-W352 HydrophobicContact CE1-CH2 4.45Å; F50-W352 AromaticContact CE1-CZ2 3.62Å; F50-W352 HydrophobicContact CE1-CZ2 3.62Å; F50-W352 HydrophobicContact CZ-CZ2 4.05Å
51Q95.6Very high92.1Very high90 Ų9053.8 Ų53.842%0.42129%0.285SS..  trans-115.3144.4-176.2-63.4-58.5-43.100110.7M270 N271Q51-M270 WeakPolarHBondContact O-CB 3.37Å; Q51-N271 HydrophobicContact CB-CB 4.3Å; Q51-N271 WeakPolarHBondContact O-CB 3.34Å; Q51-N271 PolarHBondContact O-N 3.09Å
52P96.3Very high92Very high11 Ų1154.9 Ų54.97%0.07129%0.291CS..  trans-67.6167.9174.132.4-36.7000109.9V3 P43 T54 N271V3-P52 HydrophobicContact CG1-CB 3.6Å; V3-P52 HydrophobicContact CG1-CG 3.46Å; V3-P52 VanDerWaalsContact CG1-CG 3.46Å; P43-P52 HydrophobicContact CB-CB 4.45Å; P52-T54 PolarHBondContact O-N 2.91Å; P52-N271 PolarHBondContact O-ND2 3.46Å; P52-N271 PolarHBondContact O-OD1 2.8Å
53I95.7Very high92Very high0 Ų055 Ų550%030%0.296CS..EExtended strand (participates in β ladder)trans-75.1127.2176.5-48.1178.1000109V3 V4 L55 I62 Q268 Q275V3-I53 CarbonylContact C-O 3.58Å; V3-I53 WeakPolarHBondContact CA-O 3.4Å; V4-I53 HydrophobicContact CB-CB 4.03Å; V4-I53 HydrophobicContact CG2-CB 4.11Å; V4-I53 HydrophobicContact CG2-CG2 4.47Å; V4-I53 PolarHBondContact N-O 2.76Å; I53-L55 HydrophobicContact CG2-CD2 4.2Å; I53-I62 HydrophobicContact CD1-CD1 3.64Å; I53-I62 HydrophobicContact CG2-CD1 3.89Å; I53-Q268 VanDerWaalsContact CD1-C 3.47Å; I53-Q268 WeakPolarHBondContact CD1-O 3.28Å; I53-Q275 VanDerWaalsContact CD1-NE2 3.34Å
54T95.4Very high92Very high37 Ų3756.4 Ų56.423%0.22731%0.308CS..EExtended strand (participates in β ladder)trans-104.5117.2172.5-56.30000109.9M1 P52 H56M1-T54 HydrophobicContact CE-CG2 3.92Å; M1-T54 HydrophobicContact CG-CG2 3.29Å; M1-T54 HydrophobicContact SD-CG2 3.57Å; M1-T54 VanDerWaalsContact SD-CG2 3.57Å; P52-T54 PolarHBondContact O-N 2.91Å; T54-H56 PolarHBondContact O-CD2 3.01Å
55L94.4Very high92Very high17 Ų1757.8 Ų57.89%0.08930%0.304CS..EExtended strand (participates in β ladder)trans-91.4129174.4-57.1175.4000109.9M1 N2 V4 I53 D60 I62 V63M1-L55 CarbonylContact C-O 3.52Å; M1-L55 WeakPolarHBondContact CA-O 3.26Å; N2-L55 HydrophobicContact CB-CB 4.34Å; N2-L55 PolarHBondContact N-O 2.8Å; N2-L55 WeakPolarHBondContact O-CB 3.36Å; N2-L55 PolarHBondContact O-N 3.43Å; V4-L55 HydrophobicContact CG2-CD1 3.75Å; V4-L55 HydrophobicContact CG2-CD2 4.49Å; V4-L55 HydrophobicContact CG2-CG 3.97Å; I53-L55 HydrophobicContact CG2-CD2 4.2Å; L55-D60 WeakPolarHBondContact CA-OD2 3.24Å; L55-D60 HydrophobicContact CD2-CB 4.31Å; L55-I62 HydrophobicContact CD2-CB 4.22Å; L55-V63 HydrophobicContact CD1-CG2 3.85Å; L55-V63 HydrophobicContact CD2-CG2 4.36Å
56H94.4Very high92.1Very high82 Ų8257.7 Ų57.738%0.3832%0.316SS..  trans-102.8-29.8-178.4-73.1-113.5000112.7M1 T54 D60 R285M1-H56 WeakPolarHBondContact CE-CE1 3.48Å; T54-H56 PolarHBondContact O-CD2 3.01Å; H56-D60 PolarHBondContact N-OD2 3.21Å; H56-R285 PolarHBondContact CD2-NE 3.48Å; H56-R285 VanDerWaalsContact NE2-CD 3.33Å; H56-R285 WeakPolarHBondContact NE2-CD 3.48Å
57S92.5Very high92.5Very high44 Ų4448.7 Ų48.731%0.30829%0.285SS..SBendtrans-153.6167.1-175.273.50000112.4S59 D60S57-S59 PolarHBondContact O-N 3.24Å; S57-S59 PolarHBondContact OG-N 3.07Å; S57-S59 PolarHBondContact OG-OG 2.93Å; S57-D60 PolarHBondContact N-OD1 3.24Å; S57-D60 WeakPolarHBondContact O-CB 3.18Å; S57-D60 PolarHBondContact O-N 3.21Å; S57-D60 PolarHBondContact OG-N 3.28Å; S57-D60 PolarHBondContact OG-OD1 3.17Å
58D92Very high93.2Very high139 Ų13954 Ų5474%0.74329%0.294SS*.THydrogen-bonded Turntrans-71.8-11173-61.7-27.1000112.8V63D58-V63 HydrophobicContact CB-CG1 4.33Å
59S91.1Very high93.6Very high58 Ų5855.1 Ų55.141%0.40630%0.301SS..THydrogen-bonded Turntrans-86-7.6172.7540000113.9S57 N278S57-S59 PolarHBondContact O-N 3.24Å; S57-S59 PolarHBondContact OG-N 3.07Å; S57-S59 PolarHBondContact OG-OG 2.93Å; S59-N278 WeakPolarHBondContact O-CB 3.37Å; S59-N278 PolarHBondContact O-ND2 3.21Å
60D92.8Very high93.8Very high1 Ų154.4 Ų54.41%0.00530%0.297CS..SBendtrans-61.9140.5173.8-71.825.9000109.2L55 H56 S57 I62 V63 A64 H279 E282 R285L55-D60 WeakPolarHBondContact CA-OD2 3.24Å; L55-D60 HydrophobicContact CD2-CB 4.31Å; H56-D60 PolarHBondContact N-OD2 3.21Å; S57-D60 PolarHBondContact N-OD1 3.24Å; S57-D60 WeakPolarHBondContact O-CB 3.18Å; S57-D60 PolarHBondContact O-N 3.21Å; S57-D60 PolarHBondContact OG-N 3.28Å; S57-D60 PolarHBondContact OG-OD1 3.17Å; D60-I62 VanDerWaalsContact C-N 3.32Å; D60-I62 PolarHBondContact O-N 2.99Å; D60-I62 VanDerWaalsContact O-N 3.16Å; D60-V63 PolarHBondContact O-N 3.33Å; D60-A64 PolarHBondContact O-N 3.4Å; D60-H279 IonicContact OD1-NE2 3.25Å; D60-E282 WeakPolarHBondContact CA-OE1 3.32Å; D60-R285 IonicContact OD1-NH2 3.94Å; D60-R285 PolarHBondContact OD1-NH2 3.37Å; D60-R285 IonicContact OD2-NH2 3.5Å; D60-R285 PolarHBondContact OD2-NH2 2.9Å
61W93.3Very high93.9Very high51 Ų5156.2 Ų56.219%0.19331%0.307CS..Hα-helixtrans-51-46.9-168.1179.5-85.4000113.6V63 A64 H65 E67 H266 G276 N278 E282W61-V63 PolarHBondContact O-N 2.63Å; W61-A64 PolarHBondContact O-N 2.82Å; W61-H65 HydrophobicContact CD2-CB 4.29Å; W61-H65 AromaticContact CD2-ND1 3.73Å; W61-H65 AromaticContact CE3-CE1 3.96Å; W61-H65 AromaticContact CE3-ND1 3.57Å; W61-H65 HydrophobicContact CZ2-CB 4.18Å; W61-H65 AromaticContact CZ3-CE1 3.96Å; W61-H65 AromaticContact CZ3-ND1 3.87Å; W61-H65 WeakPolarHBondContact O-CA 3.36Å; W61-H65 WeakPolarHBondContact O-CB 3.27Å; W61-H65 PolarHBondContact O-N 3.34Å; W61-E67 PolarHBondContact NE1-OE2 2.79Å; W61-H266 AromaticContact CE2-CE1 3.67Å; W61-H266 AromaticContact CE2-ND1 3.69Å; W61-H266 AromaticContact CZ2-CE1 3.36Å; W61-H266 WeakPolarHBondContact CZ2-CE1 3.36Å; W61-H266 AromaticContact CZ2-ND1 3.65Å; W61-H266 AromaticContact NE1-CE1 3.88Å; W61-H266 AromaticContact NE1-ND1 3.44Å; W61-H266 PolarHBondContact NE1-ND1 3.42Å; W61-G276 VanDerWaalsContact CB-C 3.48Å; W61-G276 WeakPolarHBondContact CB-O 3.34Å; W61-G276 VanDerWaalsContact CG-C 3.46Å; W61-N278 HydrophobicContact CE3-CB 4.37Å; W61-E282 PolarHBondContact N-OE1 3.37Å; W61-E282 PolarHBondContact N-OE2 2.8Å
62I93.4Very high94Very high29 Ų2951.9 Ų51.915%0.14929%0.287CS..Hα-helixtrans-60.7-33.4-177-71.9169.8000112.2I53 L55 D60I53-I62 HydrophobicContact CD1-CD1 3.64Å; I53-I62 HydrophobicContact CG2-CD1 3.89Å; L55-I62 HydrophobicContact CD2-CB 4.22Å; D60-I62 VanDerWaalsContact C-N 3.32Å; D60-I62 PolarHBondContact O-N 2.99Å; D60-I62 VanDerWaalsContact O-N 3.16Å
63V92.8Very high94.1Very high61 Ų6153.6 Ų53.637%0.3729%0.294SS..Hα-helixtrans-81.6-44.6178.6-177.40000110.1L55 D58 D60 W61L55-V63 HydrophobicContact CD1-CG2 3.85Å; L55-V63 HydrophobicContact CD2-CG2 4.36Å; D58-V63 HydrophobicContact CB-CG1 4.33Å; D60-V63 PolarHBondContact O-N 3.33Å; W61-V63 PolarHBondContact O-N 2.63Å
64A91.8Very high94.1Very high44 Ų4456 Ų5636%0.36431%0.313SS..Hα-helixtrans-72.4-29.7-176.300000113.7D60 W61D60-A64 PolarHBondContact O-N 3.4Å; W61-A64 PolarHBondContact O-N 2.82Å
65H90.4Very high94.2Very high69 Ų6954.2 Ų54.232%0.31930%0.302SS..SBendtrans-131.982.4-176.4-54.194000109.6W61 E67W61-H65 HydrophobicContact CD2-CB 4.29Å; W61-H65 AromaticContact CD2-ND1 3.73Å; W61-H65 AromaticContact CE3-CE1 3.96Å; W61-H65 AromaticContact CE3-ND1 3.57Å; W61-H65 HydrophobicContact CZ2-CB 4.18Å; W61-H65 AromaticContact CZ3-CE1 3.96Å; W61-H65 AromaticContact CZ3-ND1 3.87Å; W61-H65 WeakPolarHBondContact O-CA 3.36Å; W61-H65 WeakPolarHBondContact O-CB 3.27Å; W61-H65 PolarHBondContact O-N 3.34Å; H65-E67 PolarHBondContact O-N 2.91Å; H65-E67 VanDerWaalsContact O-N 3.15Å
66P91.6Very high94.3Very high117 Ų11757.4 Ų57.476%0.7631%0.314SS*.  trans-60.8118.4175.8-22.733.9000110.8
67E93.4Very high94.3Very high71 Ų7161.3 Ų61.333%0.33233%0.325SS..  trans-122.4156.5173.2-51.3159.3116.600109.3W61 H65 H266 Q268W61-E67 PolarHBondContact NE1-OE2 2.79Å; H65-E67 PolarHBondContact O-N 2.91Å; H65-E67 VanDerWaalsContact O-N 3.15Å; E67-H266 IonicContact OE1-CE1 3.98Å; E67-H266 IonicContact OE1-CG 3.36Å; E67-H266 IonicContact OE1-ND1 3.34Å; E67-H266 PolarHBondContact OE1-ND1 3.35Å; E67-H266 WeakPolarHBondContact OE2-CB 3.49Å; E67-H266 IonicContact OE2-CG 3.57Å; E67-H266 IonicContact OE2-ND1 3.72Å; E67-H266 PolarHBondContact OE2-ND1 3.37Å; E67-Q268 VanDerWaalsContact C-NE2 3.31Å; E67-Q268 VanDerWaalsContact CB-NE2 3.31Å; E67-Q268 VanDerWaalsContact O-CD 3.23Å; E67-Q268 PolarHBondContact O-NE2 3.37Å; E67-Q268 PolarHBondContact O-OE1 2.87Å
68E94.2Very high94.3Very high171 Ų17160.8 Ų60.880%0.79932%0.319SS*.  trans-77.1133.6172.2-72-61.7146.500110.5Q70E68-Q70 PolarHBondContact O-N 2.65Å
69P95.7Very high94.2Very high38 Ų3859.6 Ų59.625%0.24732%0.319CS..  trans-59.6128.9174.3-21.130.5000111.3Q268 W269P69-Q268 HydrophobicContact CB-CB 4.19Å; P69-Q268 HydrophobicContact CG-CB 4.12Å; P69-W269 HydrophobicContact CB-CD2 4.43Å; P69-W269 HydrophobicContact CB-CH2 4.15Å; P69-W269 HydrophobicContact CB-CZ2 3.53Å
70Q97.3Very high94Very high6 Ų665.6 Ų65.63%0.02833%0.334CS..  trans-87.3110.8168.9-169-166.751.700108.6E68 A74 F75 G263 K265 W269 K297E68-Q70 PolarHBondContact O-N 2.65Å; Q70-A74 HydrophobicContact CG-CB 4.23Å; Q70-F75 HydrophobicContact CG-CB 4.09Å; Q70-G263 PolarHBondContact NE2-O 2.89Å; Q70-K265 HydrophobicContact CB-CB 4.05Å; Q70-K265 HydrophobicContact CB-CD 4.24Å; Q70-K265 HydrophobicContact CG-CD 4.35Å; Q70-W269 PolarHBondContact O-NE1 3.28Å; Q70-K297 PolarHBondContact O-NZ 3.22Å
71D98Very high93.8Very high44 Ų4468.3 Ų68.324%0.23534%0.344CS..  trans-80-179.5166.658.330000111.9A14 E73 A74 F75 W269 K297A14-D71 HydrophobicContact CB-CB 3.84Å; D71-E73 PolarHBondContact OD1-N 3.3Å; D71-A74 WeakPolarHBondContact OD1-CB 3.34Å; D71-A74 PolarHBondContact OD1-N 3.42Å; D71-F75 WeakPolarHBondContact O-CB 3.48Å; D71-F75 PolarHBondContact O-N 3.18Å; D71-F75 VanDerWaalsContact O-N 3.13Å; D71-W269 HydrophobicContact CB-CZ2 3.89Å; D71-K297 VanDerWaalsContact O-CE 3.25Å; D71-K297 WeakPolarHBondContact O-CE 3.4Å
72F98.1Very high93.6Very high0 Ų068.3 Ų68.30%035%0.346CS..Hα-helixtrans-63.8-39.1177.1178.3-111.9000112.6A14 V22 L25 F75 Y76 H296 K297 V300A14-F72 WeakPolarHBondContact O-CB 3.25Å; A14-F72 PolarHBondContact O-N 3.45Å; V22-F72 HydrophobicContact CG1-CD1 3.73Å; V22-F72 HydrophobicContact CG1-CE1 3.45Å; V22-F72 VanDerWaalsContact CG1-CE1 3.45Å; V22-F72 HydrophobicContact CG1-CZ 4.5Å; L25-F72 HydrophobicContact CB-CZ 4.48Å; L25-F72 HydrophobicContact CD1-CE1 4.12Å; L25-F72 HydrophobicContact CD1-CZ 3.9Å; F72-F75 HydrophobicContact CD2-CD1 4.29Å; F72-F75 HydrophobicContact CE2-CD1 4.34Å; F72-F75 PolarHBondContact O-N 2.86Å; F72-Y76 HydrophobicContact CZ-CD2 4.11Å; F72-Y76 HydrophobicContact CZ-CG 4.44Å; F72-Y76 WeakPolarHBondContact O-CB 3.37Å; F72-Y76 PolarHBondContact O-N 3.18Å; F72-H296 AromaticContact CD1-CD2 3.57Å; F72-H296 AromaticContact CD1-NE2 3.36Å; F72-H296 WeakPolarHBondContact CD1-NE2 3.19Å; F72-H296 AromaticContact CD2-CD2 3.24Å; F72-H296 WeakPolarHBondContact CD2-CD2 3.33Å; F72-H296 AromaticContact CD2-CG 3.93Å; F72-H296 AromaticContact CD2-NE2 3.64Å; F72-H296 AromaticContact CE1-CD2 3.82Å; F72-H296 AromaticContact CE1-NE2 3.18Å; F72-H296 WeakPolarHBondContact CE1-NE2 3.37Å; F72-H296 AromaticContact CE2-CD2 3.52Å; F72-H296 AromaticContact CE2-CE1 3.92Å; F72-H296 AromaticContact CE2-NE2 3.48Å; F72-H296 WeakPolarHBondContact CE2-NE2 3.3Å; F72-H296 AromaticContact CG-CD2 3.27Å; F72-H296 WeakPolarHBondContact CG-CD2 3.39Å; F72-H296 AromaticContact CG-NE2 3.59Å; F72-H296 AromaticContact CZ-CD2 3.82Å; F72-H296 AromaticContact CZ-CE1 3.73Å; F72-H296 AromaticContact CZ-NE2 3.26Å; F72-H296 VanDerWaalsContact CZ-NE2 3.26Å; F72-H296 WeakPolarHBondContact CZ-NE2 3.33Å; F72-K297 HydrophobicContact CD2-CG 3.96Å; F72-V300 HydrophobicContact CE2-CB 4Å; F72-V300 HydrophobicContact CE2-CG1 4.2Å; F72-V300 HydrophobicContact CE2-CG2 3.83Å; F72-V300 HydrophobicContact CZ-CB 4.21Å; F72-V300 HydrophobicContact CZ-CG1 4.08Å; F72-V300 HydrophobicContact CZ-CG2 3.78Å
73E97.4Very high93.5Very high47 Ų4769.8 Ų69.822%0.2236%0.356CS..Hα-helixtrans-64.1-49.5-179.5-173.2179135.700111.8S17 L19 D71 F75 Y76 R77S17-E73 PolarHBondContact OG-OE2 3.49Å; L19-E73 VanDerWaalsContact CD1-CD 3.42Å; L19-E73 HydrophobicContact CD1-CG 4.06Å; L19-E73 WeakPolarHBondContact CD1-OE1 3.17Å; L19-E73 WeakPolarHBondContact CG-OE1 3.24Å; L19-E73 WeakPolarHBondContact CG-OE2 3.48Å; D71-E73 PolarHBondContact OD1-N 3.3Å; E73-F75 VanDerWaalsContact C-N 3.29Å; E73-F75 PolarHBondContact O-N 2.97Å; E73-Y76 PolarHBondContact O-N 3.41Å; E73-R77 HydrophobicContact CG-CG 4.44Å; E73-R77 WeakPolarHBondContact O-CB 3.4Å; E73-R77 VanDerWaalsContact O-CG 3.3Å; E73-R77 WeakPolarHBondContact O-CG 3.46Å; E73-R77 PolarHBondContact O-N 2.84Å
74A97Very high93.5Very high49 Ų4968.1 Ų68.141%0.40535%0.346SS..Hα-helixtrans-61.5-38.3177.500000111.4Q70 D71 D78Q70-A74 HydrophobicContact CG-CB 4.23Å; D71-A74 WeakPolarHBondContact OD1-CB 3.34Å; D71-A74 PolarHBondContact OD1-N 3.42Å; A74-D78 PolarHBondContact O-N 3.35Å
75F96.7Very high93.5Very high0 Ų069.9 Ų69.90%035%0.349CS..Hα-helixtrans-62.7-54.2171.8167.1-100.7000111.5Q70 D71 F72 E73 R77 D78 R81 F262 I264 K297 A301Q70-F75 HydrophobicContact CG-CB 4.09Å; D71-F75 WeakPolarHBondContact O-CB 3.48Å; D71-F75 PolarHBondContact O-N 3.18Å; D71-F75 VanDerWaalsContact O-N 3.13Å; F72-F75 HydrophobicContact CD2-CD1 4.29Å; F72-F75 HydrophobicContact CE2-CD1 4.34Å; F72-F75 PolarHBondContact O-N 2.86Å; E73-F75 VanDerWaalsContact C-N 3.29Å; E73-F75 PolarHBondContact O-N 2.97Å; F75-R77 VanDerWaalsContact C-N 3.28Å; F75-R77 PolarHBondContact O-N 2.94Å; F75-D78 WeakPolarHBondContact O-CB 3.16Å; F75-D78 PolarHBondContact O-N 3.49Å; F75-D78 VanDerWaalsContact O-N 3.14Å; F75-R81 HydrophobicContact CD2-CG 4.4Å; F75-R81 VanDerWaalsContact CE1-CD 3.43Å; F75-R81 HydrophobicContact CE1-CG 4.39Å; F75-R81 HydrophobicContact CE2-CG 3.84Å; F75-R81 HydrophobicContact CZ-CG 3.85Å; F75-R81 WeakPolarHBondContact O-CD 3.37Å; F75-F262 VanDerWaalsContact CE2-O 3.31Å; F75-F262 WeakPolarHBondContact CE2-O 3.32Å; F75-I264 HydrophobicContact CD2-CG1 4.27Å; F75-I264 HydrophobicContact CE2-CG1 3.7Å; F75-I264 HydrophobicContact CZ-CG1 4.29Å; F75-K297 HydrophobicContact CB-CD 3.79Å; F75-K297 HydrophobicContact CB-CG 3.91Å; F75-K297 HydrophobicContact CD1-CB 3.67Å; F75-K297 HydrophobicContact CD1-CD 4.16Å; F75-K297 HydrophobicContact CD1-CG 3.5Å; F75-K297 HydrophobicContact CD2-CB 4.29Å; F75-K297 HydrophobicContact CD2-CD 3.99Å; F75-K297 HydrophobicContact CD2-CG 4.21Å; F75-K297 HydrophobicContact CE1-CB 3.56Å; F75-K297 HydrophobicContact CE1-CG 3.97Å; F75-K297 WeakPolarHBondContact CE1-O 3.48Å; F75-K297 HydrophobicContact CE2-CB 4.21Å; F75-K297 HydrophobicContact CG-CB 4.02Å; F75-K297 HydrophobicContact CG-CD 3.72Å; F75-K297 HydrophobicContact CG-CG 3.61Å; F75-K297 HydrophobicContact CZ-CB 3.84Å; F75-K297 HydrophobicContact CZ-CG 4.5Å; F75-A301 HydrophobicContact CZ-CB 4.31Å
76Y96.3Very high93.3Very high85 Ų8573.9 Ų73.933%0.33338%0.379SS..Hα-helixtrans-63-36.5-172.3-173.6-97.3000112.5V22 L25 F72 E73 V300V22-Y76 HydrophobicContact CG1-CD1 4.37Å; V22-Y76 HydrophobicContact CG1-CG 4.48Å; V22-Y76 HydrophobicContact CG2-CD1 4.19Å; L25-Y76 HydrophobicContact CD1-CD1 4.45Å; L25-Y76 HydrophobicContact CD1-CD2 3.74Å; L25-Y76 HydrophobicContact CD1-CE1 4.1Å; L25-Y76 HydrophobicContact CD1-CE2 3.33Å; L25-Y76 HydrophobicContact CD1-CG 4.29Å; F72-Y76 HydrophobicContact CZ-CD2 4.11Å; F72-Y76 HydrophobicContact CZ-CG 4.44Å; F72-Y76 WeakPolarHBondContact O-CB 3.37Å; F72-Y76 PolarHBondContact O-N 3.18Å; E73-Y76 PolarHBondContact O-N 3.41Å; Y76-V300 HydrophobicContact CD2-CG1 4.01Å; Y76-V300 HydrophobicContact CE2-CG1 3.96Å
77R94.8Very high93.1Very high164 Ų16470.1 Ų70.162%0.61936%0.361SS*.THydrogen-bonded Turntrans-82.8-8.6179.7-65.3177.764.7101.55.8114.1E73 F75 P79E73-R77 HydrophobicContact CG-CG 4.44Å; E73-R77 WeakPolarHBondContact O-CB 3.4Å; E73-R77 VanDerWaalsContact O-CG 3.3Å; E73-R77 WeakPolarHBondContact O-CG 3.46Å; E73-R77 PolarHBondContact O-N 2.84Å; F75-R77 VanDerWaalsContact C-N 3.28Å; F75-R77 PolarHBondContact O-N 2.94Å; R77-P79 WeakPolarHBondContact O-CD 3.44Å
78D92.8Very high93Very high33 Ų3370.7 Ų70.718%0.17636%0.364CS..  trans-66117.2-179.5-166.2-31.4000109.4A74 F75 Y80 R81A74-D78 PolarHBondContact O-N 3.35Å; F75-D78 WeakPolarHBondContact O-CB 3.16Å; F75-D78 PolarHBondContact O-N 3.49Å; F75-D78 VanDerWaalsContact O-N 3.14Å; D78-Y80 PolarHBondContact O-N 3.42Å; D78-Y80 WeakPolarHBondContact OD1-CB 3.47Å; D78-Y80 WeakPolarHBondContact OD1-CD2 3.46Å; D78-Y80 PolarHBondContact OD1-N 2.73Å; D78-R81 HydrophobicContact CB-CB 4.31Å; D78-R81 WeakPolarHBondContact O-CB 3.47Å; D78-R81 PolarHBondContact O-N 3.33Å
79P89.7Confident93.1Very high113 Ų11364.5 Ų64.573%0.73434%0.34SS*.THydrogen-bonded Turntrans-66.6-15.718029-36000112.8R77R77-P79 WeakPolarHBondContact O-CD 3.44Å
80Y85.9Confident93.2Very high185 Ų18563.1 Ų63.173%0.72533%0.33SS*.THydrogen-bonded Turntrans-92.70.3175.5-55.3-74.2000112.8D78 K82D78-Y80 PolarHBondContact O-N 3.42Å; D78-Y80 WeakPolarHBondContact OD1-CB 3.47Å; D78-Y80 WeakPolarHBondContact OD1-CD2 3.46Å; D78-Y80 PolarHBondContact OD1-N 2.73Å; Y80-K82 PolarHBondContact O-N 2.73Å
81R89.8Confident93.2Very high57 Ų5762.9 Ų62.922%0.21533%0.329CS..  trans-60.2135171.6-175.3179.768.197.64109.6F75 D78 T83 F262F75-R81 HydrophobicContact CD2-CG 4.4Å; F75-R81 VanDerWaalsContact CE1-CD 3.43Å; F75-R81 HydrophobicContact CE1-CG 4.39Å; F75-R81 HydrophobicContact CE2-CG 3.84Å; F75-R81 HydrophobicContact CZ-CG 3.85Å; F75-R81 WeakPolarHBondContact O-CD 3.37Å; D78-R81 HydrophobicContact CB-CB 4.31Å; D78-R81 WeakPolarHBondContact O-CB 3.47Å; D78-R81 PolarHBondContact O-N 3.33Å; R81-T83 PolarHBondContact NH1-OG1 3.17Å; R81-F262 WeakPolarHBondContact CG-O 3.3Å
82K88.7Confident93.2Very high52 Ų5261.3 Ų61.323%0.22632%0.32CS..  trans-110.1139.5174.6-64.6-177.8172.2179.70110.6Y80 F170 L195 S196 G198 M261 F262Y80-K82 PolarHBondContact O-N 2.73Å; K82-F170 HydrophobicContact CB-CE2 4.06Å; K82-F170 HydrophobicContact CB-CZ 4.35Å; K82-L195 VanDerWaalsContact CE-O 3.26Å; K82-L195 WeakPolarHBondContact CE-O 3.4Å; K82-L195 PolarHBondContact NZ-O 3.14Å; K82-S196 WeakPolarHBondContact CE-O 3.2Å; K82-S196 PolarHBondContact NZ-O 3.26Å; K82-G198 VanDerWaalsContact NZ-N 3.15Å; K82-M261 WeakPolarHBondContact CB-O 3.36Å; K82-F262 PolarHBondContact N-O 3.03Å
83T91.6Very high93.2Very high59 Ų5961.3 Ų61.336%0.36232%0.32SS..  trans-126.8129.8177.7-56.10000106.1R81 A301R81-T83 PolarHBondContact NH1-OG1 3.17Å; T83-A301 WeakPolarHBondContact CG2-O 3.33Å
84P92.6Very high93.2Very high26 Ų2659.1 Ų59.117%0.16931%0.31CS..  trans-54.7141.7170.7-22.732.8000110.6H88 L124 F170 F262 A301P84-H88 WeakPolarHBondContact CA-O 3.46Å; P84-L124 HydrophobicContact CB-CD2 4.27Å; P84-L124 HydrophobicContact CB-CG 4.39Å; P84-L124 HydrophobicContact CG-CD1 4.12Å; P84-L124 HydrophobicContact CG-CD2 3.74Å; P84-L124 HydrophobicContact CG-CG 4.13Å; P84-F170 HydrophobicContact CB-CD2 4.07Å; P84-F170 HydrophobicContact CB-CE2 4.37Å; P84-F170 HydrophobicContact CG-CD2 3.78Å; P84-F170 HydrophobicContact CG-CE1 4.47Å; P84-F170 HydrophobicContact CG-CE2 3.69Å; P84-F170 HydrophobicContact CG-CG 4.22Å; P84-F170 HydrophobicContact CG-CZ 4.06Å; P84-F262 HydrophobicContact CG-CD1 4.46Å; P84-F262 HydrophobicContact CG-CE1 3.62Å; P84-F262 HydrophobicContact CG-CZ 4.26Å; P84-A301 WeakPolarHBondContact CD-O 3.09Å
85D91.3Very high93.1Very high81 Ų8157.3 Ų57.343%0.43329%0.294SS..BIsolated β-bridgetrans-129.9175.8174.767.344.5000110.1G87 H88 S89D85-G87 PolarHBondContact O-N 2.94Å; D85-G87 VanDerWaalsContact O-N 3.12Å; D85-G87 VanDerWaalsContact OD1-CA 3.3Å; D85-G87 WeakPolarHBondContact OD1-CA 3.49Å; D85-G87 PolarHBondContact OD1-N 2.96Å; D85-H88 PolarHBondContact N-O 3.42Å; D85-H88 CarbonylContact O-C 3.31Å; D85-H88 VanDerWaalsContact O-C 3.31Å; D85-H88 PolarHBondContact O-N 3.3Å; D85-H88 IonicContact OD1-CG 3.74Å; D85-H88 PolarHBondContact OD1-N 3.38Å; D85-H88 IonicContact OD1-ND1 3.02Å; D85-H88 PolarHBondContact OD1-ND1 2.72Å; D85-H88 IonicContact OD2-ND1 3.36Å; D85-H88 PolarHBondContact OD2-ND1 2.76Å; D85-S89 WeakPolarHBondContact O-CB 3.28Å; D85-S89 PolarHBondContact O-N 3.32Å
86T86Confident93Very high154 Ų15457.3 Ų57.395%0.94529%0.294SS*.THydrogen-bonded Turntrans-63.4-17.6-177.151.30000114.1
87G88.3Confident92.7Very high37 Ų3754 Ų5438%0.38129%0.285SS..THydrogen-bonded Turntrans-97.1-17.6174.600000113.8D85 D168D85-G87 PolarHBondContact O-N 2.94Å; D85-G87 VanDerWaalsContact O-N 3.12Å; D85-G87 VanDerWaalsContact OD1-CA 3.3Å; D85-G87 WeakPolarHBondContact OD1-CA 3.49Å; D85-G87 PolarHBondContact OD1-N 2.96Å; G87-D168 WeakPolarHBondContact O-CA 3.25Å; G87-D168 WeakPolarHBondContact O-CB 3.32Å
88H92Very high92.2Very high84 Ų8448.1 Ų48.139%0.38927%0.269SS..BIsolated β-bridgetrans-137.971.3-175.4-50.288.6000111.1P84 D85 K167 D168 F170P84-H88 WeakPolarHBondContact CA-O 3.46Å; D85-H88 PolarHBondContact N-O 3.42Å; D85-H88 CarbonylContact O-C 3.31Å; D85-H88 VanDerWaalsContact O-C 3.31Å; D85-H88 PolarHBondContact O-N 3.3Å; D85-H88 IonicContact OD1-CG 3.74Å; D85-H88 PolarHBondContact OD1-N 3.38Å; D85-H88 IonicContact OD1-ND1 3.02Å; D85-H88 PolarHBondContact OD1-ND1 2.72Å; D85-H88 IonicContact OD2-ND1 3.36Å; D85-H88 PolarHBondContact OD2-ND1 2.76Å; H88-K167 PolarHBondContact CD2-O 2.84Å; H88-K167 VanDerWaalsContact CD2-O 3.23Å; H88-K167 PolarHBondContact NE2-O 3.45Å; H88-D168 WeakPolarHBondContact CA-O 3.44Å; H88-F170 WeakPolarHBondContact O-CB 3.29Å
89S94.6Very high91.8Very high41 Ų4146.7 Ų46.729%0.28726%0.261SS..  trans-119.16.9-175.859.80000114.2D85 L124 S125D85-S89 WeakPolarHBondContact O-CB 3.28Å; D85-S89 PolarHBondContact O-N 3.32Å; S89-L124 WeakPolarHBondContact O-CA 3.16Å; S89-L124 WeakPolarHBondContact O-CB 3.41Å; S89-S125 PolarHBondContact O-N 2.99Å; S89-S125 VanDerWaalsContact O-N 3.12Å
90T97.8Very high90.9Very high9 Ų942 Ų426%0.05523%0.234CC..EExtended strand (participates in β ladder)trans-108.9128.4-175.6-49.70000111.7Y92 S125 E127 A169 F170T90-Y92 HydrophobicContact CG2-CD2 3.92Å; T90-Y92 HydrophobicContact CG2-CE1 4.11Å; T90-Y92 HydrophobicContact CG2-CE2 3.41Å; T90-Y92 VanDerWaalsContact CG2-CE2 3.41Å; T90-Y92 HydrophobicContact CG2-CG 4.49Å; T90-Y92 VanDerWaalsContact CG2-CZ 3.49Å; T90-S125 CarbonylContact C-O 3.46Å; T90-S125 WeakPolarHBondContact CA-O 3.49Å; T90-E127 HydrophobicContact CG2-CB 4.23Å; T90-E127 HydrophobicContact CG2-CG 3.85Å; T90-A169 CarbonylContact O-C 3.53Å; T90-A169 WeakPolarHBondContact O-CA 3.3Å; T90-F170 PolarHBondContact O-N 3.15Å
91I98.1Very high89.8Confident0 Ų040.7 Ų40.70%024%0.24CC..EExtended strand (participates in β ladder)trans-92.4121.6167.9-61.2165.6000107.6F121 L124 S125 V126 E127 F170 V173 T258I91-F121 HydrophobicContact CD1-CB 3.81Å; I91-F121 HydrophobicContact CD1-CD2 3.98Å; I91-F121 HydrophobicContact CD1-CG 3.94Å; I91-L124 HydrophobicContact CD1-CB 4.31Å; I91-L124 HydrophobicContact CD1-CD2 3.82Å; I91-L124 HydrophobicContact CG1-CD2 3.87Å; I91-S125 PolarHBondContact N-O 3.15Å; I91-V126 HydrophobicContact CB-CG1 4.32Å; I91-V126 HydrophobicContact CB-CG2 4.19Å; I91-V126 HydrophobicContact CD1-CG2 4.32Å; I91-V126 HydrophobicContact CG2-CG1 4.32Å; I91-V126 VanDerWaalsContact O-CA 3.3Å; I91-V126 WeakPolarHBondContact O-CA 3.32Å; I91-E127 PolarHBondContact O-N 3.39Å; I91-F170 HydrophobicContact CG1-CD1 4.3Å; I91-V173 HydrophobicContact CG2-CG2 4.45Å; I91-T258 HydrophobicContact CD1-CG2 3.91Å
92Y98.3Very high88.1Confident12 Ų1245 Ų455%0.04727%0.272CS..EExtended strand (participates in β ladder)trans-99.7133.4175.8-73.5-85.9000111.2T90 E127 L129 P166 D168 A169 C171 I172 V173T90-Y92 HydrophobicContact CG2-CD2 3.92Å; T90-Y92 HydrophobicContact CG2-CE1 4.11Å; T90-Y92 HydrophobicContact CG2-CE2 3.41Å; T90-Y92 VanDerWaalsContact CG2-CE2 3.41Å; T90-Y92 HydrophobicContact CG2-CG 4.49Å; T90-Y92 VanDerWaalsContact CG2-CZ 3.49Å; Y92-E127 CarbonylContact C-O 3.52Å; Y92-E127 WeakPolarHBondContact CA-O 3.43Å; Y92-E127 HydrophobicContact CD1-CB 3.83Å; Y92-E127 HydrophobicContact CE1-CB 3.7Å; Y92-E127 HydrophobicContact CE1-CG 4.34Å; Y92-E127 WeakPolarHBondContact CE1-OE2 3.48Å; Y92-E127 PolarHBondContact OH-OE2 3.16Å; Y92-L129 HydrophobicContact CD1-CD1 4.42Å; Y92-L129 HydrophobicContact CD1-CD2 3.67Å; Y92-L129 HydrophobicContact CD1-CG 3.92Å; Y92-L129 HydrophobicContact CE1-CD2 4.16Å; Y92-P166 HydrophobicContact CD1-CG 3.84Å; Y92-P166 HydrophobicContact CD2-CB 4.13Å; Y92-P166 HydrophobicContact CD2-CG 3.74Å; Y92-P166 HydrophobicContact CE1-CB 4.33Å; Y92-P166 HydrophobicContact CE1-CG 3.73Å; Y92-P166 HydrophobicContact CE2-CB 3.58Å; Y92-P166 HydrophobicContact CE2-CG 3.61Å; Y92-P166 HydrophobicContact CG-CG 3.83Å; Y92-D168 PolarHBondContact OH-OD1 2.87Å; Y92-D168 PolarHBondContact OH-OD2 3Å; Y92-A169 HydrophobicContact CD2-CB 3.45Å; Y92-A169 VanDerWaalsContact CD2-CB 3.45Å; Y92-A169 HydrophobicContact CE2-CB 3.74Å; Y92-C171 PolarHBondContact N-O 2.64Å; Y92-I172 CarbonylContact O-C 3.52Å; Y92-I172 WeakPolarHBondContact O-CA 3.27Å; Y92-V173 PolarHBondContact O-N 3.32Å
93I97.5Very high86.7Confident0 Ų044.1 Ų44.10%028%0.278CS..EExtended strand (participates in β ladder)trans-107.9120.5173.3-56.1177.4000108.7R114 V126 E127 L128 L129 V173 I175 I254I93-R114 HydrophobicContact CD1-CB 4.33Å; I93-V126 HydrophobicContact CD1-CG1 3.71Å; I93-V126 HydrophobicContact CG1-CG1 4.01Å; I93-E127 PolarHBondContact N-O 3.41Å; I93-L128 HydrophobicContact CB-CD2 3.73Å; I93-L128 HydrophobicContact CD1-CD2 4.13Å; I93-L128 HydrophobicContact CG1-CD2 4.4Å; I93-L128 HydrophobicContact CG2-CD2 4.06Å; I93-L129 PolarHBondContact O-N 3.47Å; I93-V173 CarbonylContact C-O 3.57Å; I93-V173 WeakPolarHBondContact CA-O 3.37Å; I93-V173 HydrophobicContact CB-CG2 4.36Å; I93-V173 HydrophobicContact CG1-CG2 3.81Å; I93-I175 HydrophobicContact CG2-CD1 3.65Å; I93-I175 HydrophobicContact CG2-CG1 3.8Å; I93-I175 HydrophobicContact CG2-CG2 4.33Å; I93-I254 HydrophobicContact CD1-CD1 3.79Å; I93-I254 HydrophobicContact CG1-CD1 4.44Å
94Q96.9Very high85.4Confident0 Ų046.9 Ų46.90%029%0.29CS..EExtended strand (participates in β ladder)trans-103.8109.4174.6177.464.281.700109.9I96 L129 P130 V132 F160 L161 I172 V173 G174 I175Q94-I96 HydrophobicContact CG-CD1 4.49Å; Q94-I96 HydrophobicContact CG-CG1 4.03Å; Q94-L129 HydrophobicContact CB-CD1 4.31Å; Q94-P130 PolarHBondContact NE2-O 3.36Å; Q94-V132 HydrophobicContact CG-CG2 4.37Å; Q94-F160 HydrophobicContact CG-CE1 4.32Å; Q94-L161 HydrophobicContact CB-CD2 3.66Å; Q94-L161 HydrophobicContact CG-CD2 3.72Å; Q94-I172 HydrophobicContact CB-CD1 4.41Å; Q94-V173 PolarHBondContact N-O 3.49Å; Q94-G174 CarbonylContact O-C 3.55Å; Q94-G174 VanDerWaalsContact O-CA 3.29Å; Q94-G174 WeakPolarHBondContact O-CA 3.22Å; Q94-I175 PolarHBondContact O-N 3.22Å
95T95.3Very high84.2Confident12 Ų1250.3 Ų50.37%0.07430%0.303CS..EExtended strand (participates in β ladder)trans-73.8128.4171.7-52.90000110F99 V110 A131 V132T95-F99 HydrophobicContact CG2-CD2 3.51Å; T95-F99 HydrophobicContact CG2-CE2 3.4Å; T95-F99 HydrophobicContact CG2-CG 4.44Å; T95-F99 HydrophobicContact CG2-CZ 4.24Å; T95-V110 HydrophobicContact CG2-CG2 4.47Å; T95-A131 HydrophobicContact CG2-CB 4.2Å; T95-V132 WeakPolarHBondContact O-CG2 3.42Å; T95-V132 PolarHBondContact O-N 2.95Å
96I94.6Very high83.2Confident0 Ų047.2 Ų47.20%029%0.287CS..EExtended strand (participates in β ladder)trans-122.3117.8-179.9-55.9175.2000109.9Q94 V132 T137 L157 I175 T176Q94-I96 HydrophobicContact CG-CD1 4.49Å; Q94-I96 HydrophobicContact CG-CG1 4.03Å; I96-V132 HydrophobicContact CB-CG2 4.44Å; I96-V132 HydrophobicContact CG1-CG2 3.99Å; I96-T137 HydrophobicContact CG2-CG2 3.69Å; I96-L157 HydrophobicContact CD1-CD2 4.21Å; I96-L157 HydrophobicContact CG2-CD2 4.48Å; I96-I175 PolarHBondContact N-O 2.81Å; I96-T176 VanDerWaalsContact O-CB 3.31Å; I96-T176 WeakPolarHBondContact O-CB 3.35Å; I96-T176 PolarHBondContact O-OG1 3.25Å
97G90.8Very high82.9Confident14 Ų1444.4 Ų44.414%0.14427%0.267CS..SBendtrans80.2-169.2-172.800000112.8V132 Y237G97-V132 PolarHBondContact N-O 2.89Å; G97-Y237 WeakPolarHBondContact CA-OH 3.35Å
98S84.7Confident82.9Confident42 Ų4246.5 Ų46.529%0.29426%0.263SS..  trans-86.5152.7174-1550000113G100 Y237 T239S98-G100 PolarHBondContact OG-O 3.09Å; S98-Y237 WeakPolarHBondContact CA-OH 3.48Å; S98-Y237 PolarHBondContact N-OH 2.79Å; S98-Y237 PolarHBondContact O-OH 3.38Å; S98-T239 WeakPolarHBondContact O-CG2 3.49Å
99F82.9Confident82.8Confident2 Ų242.5 Ų42.51%0.00925%0.245CC..SBendtrans-122.828178-86.4-116.2000111.3T95 T106 Y109 V110 I175 T176 M177 F204T95-F99 HydrophobicContact CG2-CD2 3.51Å; T95-F99 HydrophobicContact CG2-CE2 3.4Å; T95-F99 HydrophobicContact CG2-CG 4.44Å; T95-F99 HydrophobicContact CG2-CZ 4.24Å; F99-T106 VanDerWaalsContact C-OG1 3.23Å; F99-T106 HydrophobicContact CB-CG2 3.29Å; F99-T106 PolarHBondContact O-OG1 3.36Å; F99-Y109 AromaticContact CD1-CD1 3.88Å; F99-Y109 HydrophobicContact CD1-CD1 3.88Å; F99-Y109 AromaticContact CD1-CE1 3.68Å; F99-Y109 HydrophobicContact CD1-CE1 3.68Å; F99-Y109 HydrophobicContact CE1-CD1 4.47Å; F99-Y109 AromaticContact CE1-CE1 3.94Å; F99-Y109 HydrophobicContact CE1-CE1 3.94Å; F99-V110 HydrophobicContact CD1-CG2 4.27Å; F99-V110 HydrophobicContact CG-CG2 4.46Å; F99-I175 HydrophobicContact CE1-CD1 4.01Å; F99-I175 HydrophobicContact CE1-CG1 4.32Å; F99-I175 HydrophobicContact CE2-CG1 4.38Å; F99-I175 HydrophobicContact CZ-CB 3.9Å; F99-I175 HydrophobicContact CZ-CD1 3.81Å; F99-I175 HydrophobicContact CZ-CG1 3.64Å; F99-T176 VanDerWaalsContact CZ-CA 3.47Å; F99-M177 HydrophobicContact CB-CG 4.21Å; F99-M177 HydrophobicContact CD1-CE 3.47Å; F99-M177 VanDerWaalsContact CD1-CE 3.47Å; F99-M177 HydrophobicContact CD1-CG 3.56Å; F99-M177 HydrophobicContact CD1-SD 4.29Å; F99-M177 HydrophobicContact CD2-CG 4.15Å; F99-M177 HydrophobicContact CE1-CE 3.86Å; F99-M177 HydrophobicContact CE1-CG 3.93Å; F99-M177 HydrophobicContact CE1-SD 4.48Å; F99-M177 HydrophobicContact CE2-CG 4.46Å; F99-M177 HydrophobicContact CG-CE 4.37Å; F99-M177 HydrophobicContact CG-CG 3.67Å; F99-M177 HydrophobicContact CZ-CG 4.35Å; F99-F204 AromaticContact CE1-CD2 3.7Å; F99-F204 HydrophobicContact CE1-CD2 3.7Å; F99-F204 AromaticContact CE1-CE2 3.83Å; F99-F204 HydrophobicContact CE1-CE2 3.83Å; F99-F204 HydrophobicContact CZ-CD2 4.36Å; F99-F204 HydrophobicContact CZ-CE2 4.37Å
100G72.2Confident82.7Confident16 Ų1641 Ų4117%0.16523%0.234CC..SBendtrans152.6-174.2-173.900000111.2S98 T106 T239S98-G100 PolarHBondContact OG-O 3.09Å; G100-T106 VanDerWaalsContact CA-OG1 3.29Å; G100-T106 WeakPolarHBondContact CA-OG1 3.29Å; G100-T106 PolarHBondContact N-OG1 2.82Å; G100-T239 WeakPolarHBondContact CA-OG1 3.31Å; G100-T239 PolarHBondContact N-OG1 3.37Å
101D61.7Low82.5Confident157 Ų15742.8 Ų42.884%0.8424%0.241SC*.SBendtrans-64.9140.5156-70.5-39.5000108.6G103D101-G103 PolarHBondContact O-N 3.11Å
102V55Low82.3Confident146 Ų14643.4 Ų43.489%0.88524%0.244SC*.SBendtrans-56117.1180-178.30000109.3
103G59.4Low82.2Confident34 Ų3442.9 Ų42.935%0.35124%0.241SC..SBendtrans165178.9-17800000113.8D101 Q105 T106D101-G103 PolarHBondContact O-N 3.11Å; G103-Q105 VanDerWaalsContact C-N 3.27Å; G103-Q105 PolarHBondContact O-N 3.49Å; G103-Q105 VanDerWaalsContact O-N 3.11Å; G103-T106 PolarHBondContact O-N 3.2Å
104L63Low82.2Confident118 Ų11846.4 Ų46.462%0.61826%0.255SS*.Hα-helixtrans-55-32.8-169.9-66.6167.1000114.6T106 R108 F339L104-T106 PolarHBondContact O-N 3.4Å; L104-R108 VanDerWaalsContact O-CG 3.25Å; L104-R108 WeakPolarHBondContact O-CG 3.32Å; L104-R108 PolarHBondContact O-N 2.95Å; L104-R108 VanDerWaalsContact O-N 3.16Å; L104-F339 HydrophobicContact CB-CE2 4.34Å
105Q67.1Low82.2Confident97 Ų9749.1 Ų49.145%0.45327%0.269SS..Hα-helixtrans-63.9-41.7-178.2-71.4-172.817.500113.4G103 R108 Y109 I242 F339G103-Q105 VanDerWaalsContact C-N 3.27Å; G103-Q105 PolarHBondContact O-N 3.49Å; G103-Q105 VanDerWaalsContact O-N 3.11Å; Q105-R108 PolarHBondContact O-N 2.98Å; Q105-Y109 PolarHBondContact O-N 3.49Å; Q105-I242 HydrophobicContact CB-CD1 4.32Å; Q105-F339 HydrophobicContact CB-CD2 4.45Å; Q105-F339 HydrophobicContact CB-CE2 4.43Å; Q105-F339 HydrophobicContact CG-CD1 3.53Å; Q105-F339 HydrophobicContact CG-CD2 3.51Å; Q105-F339 HydrophobicContact CG-CE1 3.35Å; Q105-F339 HydrophobicContact CG-CE2 3.27Å; Q105-F339 HydrophobicContact CG-CG 3.64Å; Q105-F339 HydrophobicContact CG-CZ 3.18Å
106T71.6Confident82.4Confident16 Ų1648.6 Ų48.610%0.09827%0.266CS..Hα-helixtrans-70.3-42.3-176-70.70000111.3F99 G100 G103 L104 R108 Y109 V110F99-T106 VanDerWaalsContact C-OG1 3.23Å; F99-T106 HydrophobicContact CB-CG2 3.29Å; F99-T106 PolarHBondContact O-OG1 3.36Å; G100-T106 VanDerWaalsContact CA-OG1 3.29Å; G100-T106 WeakPolarHBondContact CA-OG1 3.29Å; G100-T106 PolarHBondContact N-OG1 2.82Å; G103-T106 PolarHBondContact O-N 3.2Å; L104-T106 PolarHBondContact O-N 3.4Å; T106-R108 VanDerWaalsContact C-N 3.31Å; T106-R108 PolarHBondContact O-N 2.94Å; T106-Y109 PolarHBondContact O-N 2.79Å; T106-V110 PolarHBondContact O-N 3.25Å
107D80.1Confident82.5Confident95 Ų9548.6 Ų48.651%0.50827%0.266SS..Hα-helixtrans-62-43.1176.7-63.9-23.1000110.2Y109 V110 E111D107-Y109 PolarHBondContact O-N 2.94Å; D107-V110 PolarHBondContact O-N 3.26Å; D107-E111 WeakPolarHBondContact O-CG 3.28Å; D107-E111 PolarHBondContact O-N 3.21Å
108R87.5Confident82.9Confident82 Ų8251.8 Ų51.831%0.30928%0.277SS..Hα-helixtrans-58.3-44173.9-72.1-58.292159.97113.2L104 Q105 T106 V110 E111 W112 E321L104-R108 VanDerWaalsContact O-CG 3.25Å; L104-R108 WeakPolarHBondContact O-CG 3.32Å; L104-R108 PolarHBondContact O-N 2.95Å; L104-R108 VanDerWaalsContact O-N 3.16Å; Q105-R108 PolarHBondContact O-N 2.98Å; T106-R108 VanDerWaalsContact C-N 3.31Å; T106-R108 PolarHBondContact O-N 2.94Å; R108-V110 PolarHBondContact O-N 3.23Å; R108-E111 VanDerWaalsContact CZ-CD 3.46Å; R108-E111 IonicContact CZ-OE1 3.18Å; R108-E111 IonicContact CZ-OE2 2.68Å; R108-E111 IonicContact NE-OE1 2.65Å; R108-E111 IonicContact NE-OE2 3.43Å; R108-E111 PolarHBondContact NE-OE2 3.12Å; R108-E111 IonicContact NH1-OE2 3.41Å; R108-E111 PolarHBondContact NH1-OE2 3.28Å; R108-E111 IonicContact NH2-OE1 3.31Å; R108-E111 PolarHBondContact NH2-OE1 2.93Å; R108-E111 IonicContact NH2-OE2 3.37Å; R108-E111 PolarHBondContact NH2-OE2 3.26Å; R108-E111 PolarHBondContact O-N 3.33Å; R108-W112 HydrophobicContact CB-CH2 4.27Å; R108-W112 HydrophobicContact CB-CZ2 3.93Å; R108-W112 PolarHBondContact O-N 3.38Å; R108-E321 IonicContact NH1-OE1 3.44Å
109Y89.9Confident83.5Confident0 Ų050.3 Ų50.30%027%0.268CS..Hα-helixtrans-62.5-43.1-179.5171.7-97.4000112.8F99 Q105 T106 D107 E111 W112 L113 M177 F204 I242 L247 S250F99-Y109 AromaticContact CD1-CD1 3.88Å; F99-Y109 HydrophobicContact CD1-CD1 3.88Å; F99-Y109 AromaticContact CD1-CE1 3.68Å; F99-Y109 HydrophobicContact CD1-CE1 3.68Å; F99-Y109 HydrophobicContact CE1-CD1 4.47Å; F99-Y109 AromaticContact CE1-CE1 3.94Å; F99-Y109 HydrophobicContact CE1-CE1 3.94Å; Q105-Y109 PolarHBondContact O-N 3.49Å; T106-Y109 PolarHBondContact O-N 2.79Å; D107-Y109 PolarHBondContact O-N 2.94Å; Y109-E111 VanDerWaalsContact C-N 3.33Å; Y109-W112 HydrophobicContact CD2-CE3 4.46Å; Y109-W112 PolarHBondContact O-N 3.39Å; Y109-L113 HydrophobicContact CD1-CD1 4.2Å; Y109-L113 HydrophobicContact CE1-CD1 3.57Å; Y109-L113 HydrophobicContact CE1-CG 4.38Å; Y109-L113 WeakPolarHBondContact O-CG 3.46Å; Y109-L113 PolarHBondContact O-N 2.87Å; Y109-L113 VanDerWaalsContact O-N 3.12Å; Y109-M177 HydrophobicContact CD1-CE 4.37Å; Y109-M177 HydrophobicContact CE1-CE 3.57Å; Y109-F204 HydrophobicContact CE1-CD2 4.33Å; Y109-F204 HydrophobicContact CE1-CE2 4.43Å; Y109-F204 WeakPolarHBondContact OH-CD2 3.41Å; Y109-I242 HydrophobicContact CD2-CD1 4.49Å; Y109-I242 HydrophobicContact CD2-CG1 4.12Å; Y109-I242 HydrophobicContact CD2-CG2 3.68Å; Y109-I242 HydrophobicContact CE2-CG2 4.34Å; Y109-I242 HydrophobicContact CG-CD1 4.16Å; Y109-I242 HydrophobicContact CG-CG1 4.19Å; Y109-I242 HydrophobicContact CG-CG2 4.41Å; Y109-L247 HydrophobicContact CD2-CD1 4.1Å; Y109-L247 HydrophobicContact CE2-CB 4.41Å; Y109-L247 HydrophobicContact CE2-CD1 3.82Å; Y109-S250 WeakPolarHBondContact OH-CB 3.46Å; Y109-S250 PolarHBondContact OH-OG 3.39Å
110V92.1Very high84.3Confident9 Ų950.3 Ų50.36%0.05527%0.268CS..Hα-helixtrans-68-36.3177.1178.20000111.1T95 F99 T106 D107 R108 L113 R114 L128 I175T95-V110 HydrophobicContact CG2-CG2 4.47Å; F99-V110 HydrophobicContact CD1-CG2 4.27Å; F99-V110 HydrophobicContact CG-CG2 4.46Å; T106-V110 PolarHBondContact O-N 3.25Å; D107-V110 PolarHBondContact O-N 3.26Å; R108-V110 PolarHBondContact O-N 3.23Å; V110-L113 PolarHBondContact O-N 3.44Å; V110-R114 PolarHBondContact O-N 3.02Å; V110-L128 HydrophobicContact CG1-CD1 3.82Å; V110-L128 HydrophobicContact CG1-CD2 3.66Å; V110-L128 HydrophobicContact CG1-CG 4.37Å; V110-I175 HydrophobicContact CG1-CD1 4.22Å; V110-I175 HydrophobicContact CG2-CD1 4.42Å
111E93.6Very high85.5Confident47 Ų4749.6 Ų49.622%0.2226%0.26CS..Hα-helixtrans-64.3-42.6173.1-74.2176.5-146.300112.7D107 R108 Y109 L113 R114 D115 L128D107-E111 WeakPolarHBondContact O-CG 3.28Å; D107-E111 PolarHBondContact O-N 3.21Å; R108-E111 VanDerWaalsContact CZ-CD 3.46Å; R108-E111 IonicContact CZ-OE1 3.18Å; R108-E111 IonicContact CZ-OE2 2.68Å; R108-E111 IonicContact NE-OE1 2.65Å; R108-E111 IonicContact NE-OE2 3.43Å; R108-E111 PolarHBondContact NE-OE2 3.12Å; R108-E111 IonicContact NH1-OE2 3.41Å; R108-E111 PolarHBondContact NH1-OE2 3.28Å; R108-E111 IonicContact NH2-OE1 3.31Å; R108-E111 PolarHBondContact NH2-OE1 2.93Å; R108-E111 IonicContact NH2-OE2 3.37Å; R108-E111 PolarHBondContact NH2-OE2 3.26Å; R108-E111 PolarHBondContact O-N 3.33Å; Y109-E111 VanDerWaalsContact C-N 3.33Å; E111-L113 VanDerWaalsContact C-N 3.27Å; E111-L113 PolarHBondContact O-N 3.05Å; E111-R114 WeakPolarHBondContact O-CB 3.36Å; E111-R114 PolarHBondContact O-N 3.08Å; E111-R114 VanDerWaalsContact O-N 3.09Å; E111-D115 VanDerWaalsContact O-CG 3.28Å; E111-D115 PolarHBondContact O-N 2.93Å; E111-L128 HydrophobicContact CG-CD1 4.12Å
112W95.3Very high87.1Confident13 Ų1343.5 Ų43.55%0.04923%0.229CC..Hα-helixtrans-59.1-40.2174.2-63.8-25.7000111.7R108 Y109 D115 Y116 I242 L247 W316 F339 K341 P342R108-W112 HydrophobicContact CB-CH2 4.27Å; R108-W112 HydrophobicContact CB-CZ2 3.93Å; R108-W112 PolarHBondContact O-N 3.38Å; Y109-W112 HydrophobicContact CD2-CE3 4.46Å; Y109-W112 PolarHBondContact O-N 3.39Å; W112-D115 PolarHBondContact O-N 3.36Å; W112-Y116 VanDerWaalsContact O-CB 3.3Å; W112-Y116 WeakPolarHBondContact O-CB 3.28Å; W112-Y116 PolarHBondContact O-N 2.98Å; W112-I242 HydrophobicContact CZ3-CG2 4.13Å; W112-L247 HydrophobicContact CB-CD1 4.43Å; W112-L247 HydrophobicContact CE3-CD2 4.25Å; W112-W316 HydrophobicContact CB-CZ2 4.11Å; W112-W316 WeakPolarHBondContact O-CZ2 3.35Å; W112-W316 PolarHBondContact O-NE1 2.84Å; W112-F339 HydrophobicContact CH2-CB 4.47Å; W112-K341 HydrophobicContact CB-CD 4.37Å; W112-K341 HydrophobicContact CD2-CB 4.02Å; W112-K341 HydrophobicContact CD2-CD 4.24Å; W112-K341 HydrophobicContact CD2-CG 3.74Å; W112-K341 HydrophobicContact CE3-CB 4.49Å; W112-K341 HydrophobicContact CE3-CG 4.15Å; W112-K341 HydrophobicContact CG-CD 3.89Å; W112-K341 HydrophobicContact CG-CG 3.94Å; W112-K341 HydrophobicContact CH2-CB 4.32Å; W112-K341 VanDerWaalsContact CZ2-CA 3.49Å; W112-K341 HydrophobicContact CZ2-CB 3.81Å; W112-K341 HydrophobicContact CZ2-CG 4.45Å; W112-P342 VanDerWaalsContact CZ3-CD 3.48Å; W112-P342 HydrophobicContact CZ3-CG 4.49Å
113L95.8Very high88.9Confident0 Ų040 Ų400%022%0.222CC..Hα-helixtrans-64.9-40.7174.1-69.6176.4000112.3Y109 V110 E111 C117 I175 F204 L247Y109-L113 HydrophobicContact CD1-CD1 4.2Å; Y109-L113 HydrophobicContact CE1-CD1 3.57Å; Y109-L113 HydrophobicContact CE1-CG 4.38Å; Y109-L113 WeakPolarHBondContact O-CG 3.46Å; Y109-L113 PolarHBondContact O-N 2.87Å; Y109-L113 VanDerWaalsContact O-N 3.12Å; V110-L113 PolarHBondContact O-N 3.44Å; E111-L113 VanDerWaalsContact C-N 3.27Å; E111-L113 PolarHBondContact O-N 3.05Å; L113-C117 WeakPolarHBondContact O-CB 3.23Å; L113-C117 PolarHBondContact O-N 2.55Å; L113-I175 HydrophobicContact CD1-CD1 4.21Å; L113-F204 HydrophobicContact CD1-CE2 3.66Å; L113-F204 HydrophobicContact CD1-CZ 3.97Å; L113-L247 HydrophobicContact CD2-CD1 3.98Å; L113-L247 HydrophobicContact CG-CD1 4.45Å
114R97.3Very high90.7Very high75 Ų7538.9 Ų38.928%0.28321%0.209SC..Hα-helixtrans-59.5-51174.6-177.1-83.4-62.5-105.30.4110.9I93 V110 E111 Y116 C117 Q118 V126 L128I93-R114 HydrophobicContact CD1-CB 4.33Å; V110-R114 PolarHBondContact O-N 3.02Å; E111-R114 WeakPolarHBondContact O-CB 3.36Å; E111-R114 PolarHBondContact O-N 3.08Å; E111-R114 VanDerWaalsContact O-N 3.09Å; R114-Y116 PolarHBondContact O-N 3.31Å; R114-C117 WeakPolarHBondContact O-CB 3.33Å; R114-C117 PolarHBondContact O-N 2.76Å; R114-Q118 PolarHBondContact O-N 2.84Å; R114-V126 WeakPolarHBondContact CD-O 3.05Å; R114-V126 HydrophobicContact CG-CB 4.12Å; R114-V126 HydrophobicContact CG-CG1 3.87Å; R114-L128 HydrophobicContact CB-CD1 4.43Å; R114-L128 HydrophobicContact CB-CD2 3.83Å; R114-L128 HydrophobicContact CB-CG 4.13Å; R114-L128 HydrophobicContact CG-CD2 4.08Å; R114-L128 HydrophobicContact CG-CG 4.07Å
115D97.6Very high92.3Very high57 Ų5736 Ų3631%0.30520%0.198SC..Hα-helixtrans-65-41.1-177-64.4-17.1000111.2E111 W112 Q118 A119E111-D115 VanDerWaalsContact O-CG 3.28Å; E111-D115 PolarHBondContact O-N 2.93Å; W112-D115 PolarHBondContact O-N 3.36Å; D115-Q118 PolarHBondContact O-N 3.25Å; D115-A119 WeakPolarHBondContact O-CB 3.28Å; D115-A119 PolarHBondContact O-N 3.26Å
116Y98.3Very high93.8Very high1 Ų131.5 Ų31.50%0.00418%0.177CC..Hα-helixtrans-60.8-48.1173.3172.2-98.5000111.5W112 R114 Q118 A119 F120 C251 I254 T255 L288 L313 W316W112-Y116 VanDerWaalsContact O-CB 3.3Å; W112-Y116 WeakPolarHBondContact O-CB 3.28Å; W112-Y116 PolarHBondContact O-N 2.98Å; R114-Y116 PolarHBondContact O-N 3.31Å; Y116-Q118 VanDerWaalsContact C-N 3.27Å; Y116-Q118 PolarHBondContact O-N 3.48Å; Y116-A119 PolarHBondContact O-N 3.23Å; Y116-F120 HydrophobicContact CE1-CB 4.45Å; Y116-F120 HydrophobicContact CE1-CD2 4.38Å; Y116-F120 HydrophobicContact CE2-CD2 4.37Å; Y116-F120 AromaticContact CZ-CD2 3.77Å; Y116-F120 WeakPolarHBondContact O-CB 3.13Å; Y116-F120 PolarHBondContact O-N 2.87Å; Y116-F120 VanDerWaalsContact OH-CD2 3.25Å; Y116-F120 WeakPolarHBondContact OH-CD2 3.37Å; Y116-C251 HydrophobicContact CD1-CB 3.72Å; Y116-C251 VanDerWaalsContact CD1-SG 3.56Å; Y116-C251 HydrophobicContact CD2-CB 4.25Å; Y116-C251 HydrophobicContact CE1-CB 3.44Å; Y116-C251 VanDerWaalsContact CE1-CB 3.44Å; Y116-C251 WeakPolarHBondContact CE1-O 3.14Å; Y116-C251 HydrophobicContact CE2-CB 4.01Å; Y116-C251 HydrophobicContact CG-CB 4.12Å; Y116-C251 VanDerWaalsContact CG-SG 3.53Å; Y116-I254 HydrophobicContact CD1-CG2 4.04Å; Y116-I254 HydrophobicContact CE1-CG2 4.06Å; Y116-T255 VanDerWaalsContact CE1-OG1 3.24Å; Y116-T255 WeakPolarHBondContact CE1-OG1 3.21Å; Y116-T255 PolarHBondContact OH-OG1 3.08Å; Y116-L288 HydrophobicContact CE2-CD2 4.16Å; Y116-L288 HydrophobicContact CE2-CG 4.5Å; Y116-L288 VanDerWaalsContact OH-CD1 3.22Å; Y116-L288 WeakPolarHBondContact OH-CD1 3.48Å; Y116-L288 WeakPolarHBondContact OH-CG 3.37Å; Y116-L313 HydrophobicContact CD2-CD2 4.08Å; Y116-L313 HydrophobicContact CE2-CD2 3.76Å; Y116-W316 HydrophobicContact CD2-CD2 4.12Å; Y116-W316 AromaticContact CD2-CE3 3.81Å; Y116-W316 HydrophobicContact CD2-CE3 3.81Å; Y116-W316 HydrophobicContact CD2-CH2 4.15Å; Y116-W316 HydrophobicContact CD2-CZ2 4.43Å; Y116-W316 AromaticContact CD2-CZ3 3.85Å; Y116-W316 HydrophobicContact CD2-CZ3 3.85Å; Y116-W316 HydrophobicContact CG-CH2 4.41Å; Y116-W316 HydrophobicContact CG-CZ2 4.36Å
117C98Very high95.1Very high0 Ų035.2 Ų35.20%019%0.193CC..Hα-helixtrans-58.5-43179.8-172.10000110.5L113 R114 F120 F121 V126 I254L113-C117 WeakPolarHBondContact O-CB 3.23Å; L113-C117 PolarHBondContact O-N 2.55Å; R114-C117 WeakPolarHBondContact O-CB 3.33Å; R114-C117 PolarHBondContact O-N 2.76Å; C117-F120 PolarHBondContact O-N 2.79Å; C117-F121 VanDerWaalsContact O-CD2 3.32Å; C117-F121 WeakPolarHBondContact O-CD2 3.17Å; C117-F121 PolarHBondContact O-N 3.19Å; C117-V126 HydrophobicContact CB-CG1 4.2Å; C117-V126 HydrophobicContact CB-CG2 4.33Å; C117-I254 HydrophobicContact CB-CD1 4.1Å
118Q98.1Very high95.9Very high80 Ų8033.7 Ų33.737%0.37419%0.185SC..Hα-helixtrans-65.8-41.6176.8-170.8165.9-90.700112.6R114 D115 Y116 F120 F121 C122 V126R114-Q118 PolarHBondContact O-N 2.84Å; D115-Q118 PolarHBondContact O-N 3.25Å; Y116-Q118 VanDerWaalsContact C-N 3.27Å; Y116-Q118 PolarHBondContact O-N 3.48Å; Q118-F120 VanDerWaalsContact C-N 3.32Å; Q118-F120 PolarHBondContact O-N 3.39Å; Q118-F121 CarbonylContact O-C 3.57Å; Q118-C122 PolarHBondContact O-N 3.4Å; Q118-V126 VanDerWaalsContact CA-CG2 3.48Å; Q118-V126 HydrophobicContact CB-CB 4.08Å; Q118-V126 HydrophobicContact CB-CG2 3.62Å; Q118-V126 HydrophobicContact CG-CG2 4.18Å
119A98.2Very high96.3Very high12 Ų1231.3 Ų31.310%0.09918%0.178CC..Hα-helixtrans-63.1-39.6175.100000111.8D115 Y116 A312 L313 W316D115-A119 WeakPolarHBondContact O-CB 3.28Å; D115-A119 PolarHBondContact O-N 3.26Å; Y116-A119 PolarHBondContact O-N 3.23Å; A119-A312 HydrophobicContact CB-CB 3.97Å; A119-L313 HydrophobicContact CB-CD2 3.99Å; A119-L313 HydrophobicContact CB-CG 4.37Å; A119-W316 HydrophobicContact CB-CB 4.49Å
120F98.6Very high96.5Very high1 Ų136 Ų360%0.00421%0.209CC..Hα-helixtrans-72.7-46.8-179.2-162.5-78000112.5Y116 C117 Q118 C122 T255 V273 L290 L298 R309 L313Y116-F120 HydrophobicContact CE1-CB 4.45Å; Y116-F120 HydrophobicContact CE1-CD2 4.38Å; Y116-F120 HydrophobicContact CE2-CD2 4.37Å; Y116-F120 AromaticContact CZ-CD2 3.77Å; Y116-F120 WeakPolarHBondContact O-CB 3.13Å; Y116-F120 PolarHBondContact O-N 2.87Å; Y116-F120 VanDerWaalsContact OH-CD2 3.25Å; Y116-F120 WeakPolarHBondContact OH-CD2 3.37Å; C117-F120 PolarHBondContact O-N 2.79Å; Q118-F120 VanDerWaalsContact C-N 3.32Å; Q118-F120 PolarHBondContact O-N 3.39Å; F120-C122 PolarHBondContact O-N 3.12Å; F120-T255 HydrophobicContact CD1-CG2 4.1Å; F120-T255 HydrophobicContact CD2-CG2 4.19Å; F120-T255 WeakPolarHBondContact CD2-OG1 3.4Å; F120-T255 HydrophobicContact CE1-CG2 3.44Å; F120-T255 VanDerWaalsContact CE1-CG2 3.44Å; F120-T255 HydrophobicContact CE2-CG2 3.51Å; F120-T255 HydrophobicContact CG-CG2 4.45Å; F120-T255 HydrophobicContact CZ-CG2 3.09Å; F120-V273 HydrophobicContact CZ-CG1 4.36Å; F120-L290 HydrophobicContact CE1-CD1 4.12Å; F120-L290 HydrophobicContact CE1-CG 4.33Å; F120-L290 HydrophobicContact CZ-CD1 4.24Å; F120-L290 HydrophobicContact CZ-CG 3.99Å; F120-L298 HydrophobicContact CD1-CD2 4.46Å; F120-L298 HydrophobicContact CE1-CD2 4.1Å; F120-R309 VanDerWaalsContact O-CD 3.28Å; F120-R309 WeakPolarHBondContact O-CD 3.49Å; F120-R309 PolarHBondContact O-NE 3.48Å; F120-L313 HydrophobicContact CB-CD2 4.02Å; F120-L313 HydrophobicContact CD2-CD1 4.14Å; F120-L313 HydrophobicContact CD2-CD2 4Å; F120-L313 HydrophobicContact CG-CD2 4.47Å
121F97.7Very high96.5Very high2 Ų238.9 Ų38.91%0.00923%0.234CC..THydrogen-bonded Turntrans-93.155.7177.2-61.8-73.3000110.1I91 C117 Q118 G123 L124 T258 F262 L298I91-F121 HydrophobicContact CD1-CB 3.81Å; I91-F121 HydrophobicContact CD1-CD2 3.98Å; I91-F121 HydrophobicContact CD1-CG 3.94Å; C117-F121 VanDerWaalsContact O-CD2 3.32Å; C117-F121 WeakPolarHBondContact O-CD2 3.17Å; C117-F121 PolarHBondContact O-N 3.19Å; Q118-F121 CarbonylContact O-C 3.57Å; F121-G123 PolarHBondContact O-N 3.46Å; F121-L124 HydrophobicContact CB-CD1 4.31Å; F121-L124 WeakPolarHBondContact O-CB 3.28Å; F121-L124 WeakPolarHBondContact O-CD1 3.43Å; F121-L124 PolarHBondContact O-N 2.83Å; F121-L124 VanDerWaalsContact O-N 3.09Å; F121-T258 HydrophobicContact CD1-CG2 4.39Å; F121-T258 HydrophobicContact CD2-CG2 3.9Å; F121-T258 HydrophobicContact CE1-CG2 4Å; F121-T258 VanDerWaalsContact CE2-CB 3.49Å; F121-T258 HydrophobicContact CE2-CG2 3.47Å; F121-T258 VanDerWaalsContact CE2-CG2 3.47Å; F121-T258 HydrophobicContact CG-CG2 4.36Å; F121-T258 VanDerWaalsContact CZ-CB 3.44Å; F121-T258 HydrophobicContact CZ-CG2 3.53Å; F121-F262 HydrophobicContact CD1-CD2 4.46Å; F121-F262 AromaticContact CD1-CE2 3.47Å; F121-F262 HydrophobicContact CD1-CE2 3.47Å; F121-F262 VanDerWaalsContact CD1-CE2 3.47Å; F121-F262 AromaticContact CD1-CZ 3.81Å; F121-F262 HydrophobicContact CD1-CZ 3.81Å; F121-F262 HydrophobicContact CE1-CD2 4.22Å; F121-F262 AromaticContact CE1-CE2 3.59Å; F121-F262 HydrophobicContact CE1-CE2 3.59Å; F121-F262 HydrophobicContact CE1-CZ 4.37Å; F121-F262 HydrophobicContact CG-CE2 4.44Å; F121-L298 HydrophobicContact CD1-CD1 4.1Å; F121-L298 HydrophobicContact CD1-CD2 4.25Å; F121-L298 HydrophobicContact CE1-CD1 4.19Å; F121-L298 HydrophobicContact CE1-CD2 4.26Å
122C95.4Very high96.6Very high29 Ų2936.9 Ų36.920%0.19623%0.225CC..THydrogen-bonded Turntrans-51.6131.1-175.8-172.70000111.6Q118 F120 F304 R309Q118-C122 PolarHBondContact O-N 3.4Å; F120-C122 PolarHBondContact O-N 3.12Å; C122-F304 HydrophobicContact CB-CB 3.98Å; C122-F304 HydrophobicContact CB-CD1 4.4Å; C122-F304 HydrophobicContact CB-CG 4.05Å; C122-F304 WeakPolarHBondContact O-CD1 3.49Å; C122-R309 HydrophobicContact CB-CB 3.84Å; C122-R309 HydrophobicContact CB-CG 4.03Å
123G93.3Very high96.5Very high71 Ų7138.5 Ų38.573%0.73224%0.238SC*.THydrogen-bonded Turntrans96.8-11.2-176.500000114.6F121F121-G123 PolarHBondContact O-N 3.46Å
124L96.3Very high96.5Very high12 Ų1238.8 Ų38.86%0.06324%0.239CC..SBendtrans-100.6150.5172.1-68.382.2000110.8P84 S89 I91 F121 F170 F262P84-L124 HydrophobicContact CB-CD2 4.27Å; P84-L124 HydrophobicContact CB-CG 4.39Å; P84-L124 HydrophobicContact CG-CD1 4.12Å; P84-L124 HydrophobicContact CG-CD2 3.74Å; P84-L124 HydrophobicContact CG-CG 4.13Å; S89-L124 WeakPolarHBondContact O-CA 3.16Å; S89-L124 WeakPolarHBondContact O-CB 3.41Å; I91-L124 HydrophobicContact CD1-CB 4.31Å; I91-L124 HydrophobicContact CD1-CD2 3.82Å; I91-L124 HydrophobicContact CG1-CD2 3.87Å; F121-L124 HydrophobicContact CB-CD1 4.31Å; F121-L124 WeakPolarHBondContact O-CB 3.28Å; F121-L124 WeakPolarHBondContact O-CD1 3.43Å; F121-L124 PolarHBondContact O-N 2.83Å; F121-L124 VanDerWaalsContact O-N 3.09Å; L124-F170 HydrophobicContact CD2-CB 4.4Å; L124-F170 HydrophobicContact CD2-CD1 3.88Å; L124-F170 HydrophobicContact CD2-CE1 4.45Å; L124-F170 HydrophobicContact CD2-CG 4.16Å; L124-F262 HydrophobicContact CD1-CZ 4.3Å; L124-F262 HydrophobicContact CD2-CZ 4Å
125S97.1Very high96.4Very high57 Ų5738.2 Ų38.240%0.39925%0.247SC..EExtended strand (participates in β ladder)trans-83.3142.8168.6-65.80000109.8S89 T90 I91S89-S125 PolarHBondContact O-N 2.99Å; S89-S125 VanDerWaalsContact O-N 3.12Å; T90-S125 CarbonylContact C-O 3.46Å; T90-S125 WeakPolarHBondContact CA-O 3.49Å; I91-S125 PolarHBondContact N-O 3.15Å
126V98.3Very high96.3Very high3 Ų340.3 Ų40.32%0.01826%0.255CS..EExtended strand (participates in β ladder)trans-122.9122173.2-168.50000110.5I91 I93 R114 C117 Q118I91-V126 HydrophobicContact CB-CG1 4.32Å; I91-V126 HydrophobicContact CB-CG2 4.19Å; I91-V126 HydrophobicContact CD1-CG2 4.32Å; I91-V126 HydrophobicContact CG2-CG1 4.32Å; I91-V126 VanDerWaalsContact O-CA 3.3Å; I91-V126 WeakPolarHBondContact O-CA 3.32Å; I93-V126 HydrophobicContact CD1-CG1 3.71Å; I93-V126 HydrophobicContact CG1-CG1 4.01Å; R114-V126 WeakPolarHBondContact CD-O 3.05Å; R114-V126 HydrophobicContact CG-CB 4.12Å; R114-V126 HydrophobicContact CG-CG1 3.87Å; C117-V126 HydrophobicContact CB-CG1 4.2Å; C117-V126 HydrophobicContact CB-CG2 4.33Å; Q118-V126 VanDerWaalsContact CA-CG2 3.48Å; Q118-V126 HydrophobicContact CB-CB 4.08Å; Q118-V126 HydrophobicContact CB-CG2 3.62Å; Q118-V126 HydrophobicContact CG-CG2 4.18Å
127E98.1Very high96.2Very high93 Ų9341 Ų4144%0.43526%0.259SS..EExtended strand (participates in β ladder)trans-120.8138.9-175.6-66.2-168.217300111.8T90 I91 Y92 I93T90-E127 HydrophobicContact CG2-CB 4.23Å; T90-E127 HydrophobicContact CG2-CG 3.85Å; I91-E127 PolarHBondContact O-N 3.39Å; Y92-E127 CarbonylContact C-O 3.52Å; Y92-E127 WeakPolarHBondContact CA-O 3.43Å; Y92-E127 HydrophobicContact CD1-CB 3.83Å; Y92-E127 HydrophobicContact CE1-CB 3.7Å; Y92-E127 HydrophobicContact CE1-CG 4.34Å; Y92-E127 WeakPolarHBondContact CE1-OE2 3.48Å; Y92-E127 PolarHBondContact OH-OE2 3.16Å; I93-E127 PolarHBondContact N-O 3.41Å
128L96.9Very high96.1Very high64 Ų6443.2 Ų43.234%0.33528%0.282SS..EExtended strand (participates in β ladder)trans-88.3126.2171.9-61.7-177.6000109.4I93 V110 E111 R114I93-L128 HydrophobicContact CB-CD2 3.73Å; I93-L128 HydrophobicContact CD1-CD2 4.13Å; I93-L128 HydrophobicContact CG1-CD2 4.4Å; I93-L128 HydrophobicContact CG2-CD2 4.06Å; V110-L128 HydrophobicContact CG1-CD1 3.82Å; V110-L128 HydrophobicContact CG1-CD2 3.66Å; V110-L128 HydrophobicContact CG1-CG 4.37Å; E111-L128 HydrophobicContact CG-CD1 4.12Å; R114-L128 HydrophobicContact CB-CD1 4.43Å; R114-L128 HydrophobicContact CB-CD2 3.83Å; R114-L128 HydrophobicContact CB-CG 4.13Å; R114-L128 HydrophobicContact CG-CD2 4.08Å; R114-L128 HydrophobicContact CG-CG 4.07Å
129L96.1Very high96Very high32 Ų3239.4 Ų39.417%0.16826%0.264CS..EExtended strand (participates in β ladder)trans-81.2153.8166.3-65.2176.8000109.9Y92 I93 Q94 A131 P166 I172Y92-L129 HydrophobicContact CD1-CD1 4.42Å; Y92-L129 HydrophobicContact CD1-CD2 3.67Å; Y92-L129 HydrophobicContact CD1-CG 3.92Å; Y92-L129 HydrophobicContact CE1-CD2 4.16Å; I93-L129 PolarHBondContact O-N 3.47Å; Q94-L129 HydrophobicContact CB-CD1 4.31Å; L129-A131 PolarHBondContact O-N 3.28Å; L129-P166 HydrophobicContact CD2-CG 4.48Å; L129-I172 HydrophobicContact CD1-CD1 3.64Å; L129-I172 HydrophobicContact CD1-CG1 4.42Å
130P93.9Very high96Very high98 Ų9840.8 Ų40.864%0.63627%0.273SS*.EExtended strand (participates in β ladder)trans-52.5131.9174.4-2634.5000111.1Q94Q94-P130 PolarHBondContact NE2-O 3.36Å
131A93.4Very high95.8Very high70 Ų7040.8 Ų40.858%0.57927%0.273SS*.EExtended strand (participates in β ladder)trans-57.4141.3177.700000110.6T95 L129T95-A131 HydrophobicContact CG2-CB 4.2Å; L129-A131 PolarHBondContact O-N 3.28Å
132V94.7Very high95.6Very high5 Ų542.8 Ų42.83%0.0328%0.281CS..EExtended strand (participates in β ladder)trans-119.5143.9178.5-62.10000110.2Q94 T95 I96 G97 E136 T137 F160Q94-V132 HydrophobicContact CG-CG2 4.37Å; T95-V132 WeakPolarHBondContact O-CG2 3.42Å; T95-V132 PolarHBondContact O-N 2.95Å; I96-V132 HydrophobicContact CB-CG2 4.44Å; I96-V132 HydrophobicContact CG1-CG2 3.99Å; G97-V132 PolarHBondContact N-O 2.89Å; V132-E136 HydrophobicContact CB-CB 4.35Å; V132-T137 HydrophobicContact CG2-CG2 4.31Å; V132-F160 HydrophobicContact CB-CZ 4.29Å; V132-F160 HydrophobicContact CG1-CZ 4.14Å; V132-F160 HydrophobicContact CG2-CE1 3.91Å; V132-F160 HydrophobicContact CG2-CZ 3.85Å
133S94.5Very high95.4Very high46 Ų4643.6 Ų43.632%0.32229%0.285SS..  trans-68.5159.1170.968.60000111.2S135 E136S133-S135 PolarHBondContact O-N 3.29Å; S133-S135 PolarHBondContact OG-OG 2.86Å; S133-E136 WeakPolarHBondContact CB-OE2 3.25Å; S133-E136 PolarHBondContact N-OE2 3.05Å; S133-E136 PolarHBondContact O-N 3.14Å; S133-E136 WeakPolarHBondContact OG-CG 3.45Å; S133-E136 PolarHBondContact OG-N 3.49Å; S133-E136 PolarHBondContact OG-OE2 3.37Å
134V95.1Very high95.3Very high6 Ų640.4 Ų40.44%0.03625%0.251CS..Hα-helixtrans-58.6-36.3173.2-171.10000110.8E136 T137 I152 I178 Y231 F234V134-E136 VanDerWaalsContact C-N 3.33Å; V134-E136 PolarHBondContact O-N 3.06Å; V134-T137 WeakPolarHBondContact O-CB 3.36Å; V134-T137 PolarHBondContact O-N 2.87Å; V134-T137 VanDerWaalsContact O-N 3.15Å; V134-T137 PolarHBondContact O-OG1 2.93Å; V134-I152 HydrophobicContact CG1-CG2 4.02Å; V134-I178 HydrophobicContact CG2-CD1 3.31Å; V134-Y231 HydrophobicContact CB-CD1 4.28Å; V134-Y231 HydrophobicContact CG1-CD1 3.86Å; V134-Y231 HydrophobicContact CG1-CE1 4.07Å; V134-F234 HydrophobicContact CB-CB 4.41Å; V134-F234 HydrophobicContact CB-CD2 4.02Å; V134-F234 HydrophobicContact CB-CE2 4.46Å; V134-F234 HydrophobicContact CB-CG 4.11Å; V134-F234 HydrophobicContact CG1-CD1 4.46Å; V134-F234 HydrophobicContact CG1-CD2 3.79Å; V134-F234 HydrophobicContact CG1-CE1 4.4Å; V134-F234 HydrophobicContact CG1-CE2 3.72Å; V134-F234 HydrophobicContact CG1-CG 4.17Å; V134-F234 HydrophobicContact CG1-CZ 4.04Å; V134-F234 HydrophobicContact CG2-CB 4.1Å; V134-F234 HydrophobicContact CG2-CD1 4.1Å; V134-F234 HydrophobicContact CG2-CD2 4.35Å; V134-F234 HydrophobicContact CG2-CG 3.93Å
135S95.4Very high94.8Very high63 Ų6344.4 Ų44.444%0.44128%0.28SS..Hα-helixtrans-62.6-36.3-179.671.40000113.7S133 T137 G138 Y231S133-S135 PolarHBondContact O-N 3.29Å; S133-S135 PolarHBondContact OG-OG 2.86Å; S135-T137 PolarHBondContact O-N 3.44Å; S135-G138 PolarHBondContact O-N 3.45Å; S135-Y231 VanDerWaalsContact CA-CG 3.48Å
136E96.1Very high94.3Very high102 Ų10245.6 Ų45.648%0.47729%0.288SS..Hα-helixtrans-67.8-24177.9-74.4166.183.200113V132 S133 V134 G138 F160V132-E136 HydrophobicContact CB-CB 4.35Å; S133-E136 WeakPolarHBondContact CB-OE2 3.25Å; S133-E136 PolarHBondContact N-OE2 3.05Å; S133-E136 PolarHBondContact O-N 3.14Å; S133-E136 WeakPolarHBondContact OG-CG 3.45Å; S133-E136 PolarHBondContact OG-N 3.49Å; S133-E136 PolarHBondContact OG-OE2 3.37Å; V134-E136 VanDerWaalsContact C-N 3.33Å; V134-E136 PolarHBondContact O-N 3.06Å; E136-G138 VanDerWaalsContact C-N 3.29Å; E136-F160 WeakPolarHBondContact O-CE2 3.34Å
137T96.2Very high93.7Very high14 Ų1446.1 Ų46.19%0.08629%0.292CS..Hα-helixtrans-72.9-25.9176.7740000112.3I96 V132 V134 S135 C139 L157 F160I96-T137 HydrophobicContact CG2-CG2 3.69Å; V132-T137 HydrophobicContact CG2-CG2 4.31Å; V134-T137 WeakPolarHBondContact O-CB 3.36Å; V134-T137 PolarHBondContact O-N 2.87Å; V134-T137 VanDerWaalsContact O-N 3.15Å; V134-T137 PolarHBondContact O-OG1 2.93Å; S135-T137 PolarHBondContact O-N 3.44Å; T137-C139 PolarHBondContact O-N 2.83Å; T137-C139 WeakPolarHBondContact OG1-CB 3.23Å; T137-C139 PolarHBondContact OG1-N 2.78Å; T137-C139 VanDerWaalsContact OG1-N 3.14Å; T137-C139 PolarHBondContact OG1-SG 2.81Å; T137-L157 HydrophobicContact CG2-CD2 3.89Å; T137-F160 HydrophobicContact CG2-CD1 4.27Å; T137-F160 HydrophobicContact CG2-CE1 4.24Å; T137-F160 HydrophobicContact CG2-CG 4.43Å; T137-F160 HydrophobicContact CG2-CZ 4.35Å
138G95.7Very high93.3Very high47 Ų4745.5 Ų45.549%0.48529%0.289SS..THydrogen-bonded Turntrans61.620.4-171.500000113.4S135 E136 Y231S135-G138 PolarHBondContact O-N 3.45Å; E136-G138 VanDerWaalsContact C-N 3.29Å; G138-Y231 VanDerWaalsContact CA-OH 3.27Å; G138-Y231 WeakPolarHBondContact CA-OH 3.39Å; G138-Y231 PolarHBondContact O-OH 2.81Å
139C96.2Very high93Very high0 Ų042.8 Ų42.80%028%0.275CS..  trans-70.9147.2-175.870.80000112.6T137 D156 L157 Y231T137-C139 PolarHBondContact O-N 2.83Å; T137-C139 WeakPolarHBondContact OG1-CB 3.23Å; T137-C139 PolarHBondContact OG1-N 2.78Å; T137-C139 VanDerWaalsContact OG1-N 3.14Å; T137-C139 PolarHBondContact OG1-SG 2.81Å; C139-D156 HydrophobicContact CB-CB 3.77Å; C139-L157 HydrophobicContact CB-CD2 3.72Å; C139-L157 HydrophobicContact CB-CG 4.32Å; C139-Y231 PolarHBondContact N-OH 3.14Å; C139-Y231 WeakPolarHBondContact O-CE1 3.36Å; C139-Y231 PolarHBondContact O-OH 2.64Å
140S96.3Very high92.9Very high41 Ų4142.2 Ų42.229%0.28727%0.272SS..  trans-67147166.5-51.80000110.4L153 D156S140-L153 PolarHBondContact O-N 3.02Å; S140-D156 VanDerWaalsContact CB-OD2 3.3Å; S140-D156 WeakPolarHBondContact CB-OD2 3.3Å; S140-D156 PolarHBondContact N-OD2 3.13Å; S140-D156 PolarHBondContact OG-OD2 3.24Å
141F95.6Very high92.9Very high1 Ų137.5 Ų37.50%0.00424%0.241CC..EExtended strand (participates in β ladder)trans-141.4159.2178.255.7-92.8000113.1Q151 I152 L226 R227 Q228 D230 Y231 V233 F234F141-Q151 CarbonylContact C-O 3.48Å; F141-Q151 WeakPolarHBondContact CA-O 3.48Å; F141-Q151 VanDerWaalsContact CB-O 3.25Å; F141-Q151 WeakPolarHBondContact CB-O 3.19Å; F141-I152 HydrophobicContact CB-CG2 4.03Å; F141-L226 HydrophobicContact CD2-CD1 4.08Å; F141-L226 HydrophobicContact CD2-CD2 4.22Å; F141-L226 HydrophobicContact CE2-CB 4.25Å; F141-L226 HydrophobicContact CE2-CD1 4.41Å; F141-L226 HydrophobicContact CE2-CD2 3.97Å; F141-L226 HydrophobicContact CE2-CG 4.45Å; F141-R227 WeakPolarHBondContact CZ-O 3.45Å; F141-Q228 PolarHBondContact O-NE2 3.39Å; F141-D230 WeakPolarHBondContact CZ-O 3.48Å; F141-Y231 HydrophobicContact CD1-CD1 4.15Å; F141-Y231 AromaticContact CD1-CE1 3.72Å; F141-Y231 HydrophobicContact CD1-CE1 3.72Å; F141-Y231 AromaticContact CE1-CD1 3.82Å; F141-Y231 HydrophobicContact CE1-CD1 3.82Å; F141-Y231 AromaticContact CE1-CE1 3.6Å; F141-Y231 HydrophobicContact CE1-CE1 3.6Å; F141-Y231 HydrophobicContact CE1-CG 4.4Å; F141-V233 HydrophobicContact CD2-CG2 4.26Å; F141-V233 HydrophobicContact CE2-CG2 3.84Å; F141-V233 HydrophobicContact CZ-CG2 4.24Å; F141-F234 HydrophobicContact CB-CE2 4.06Å; F141-F234 HydrophobicContact CB-CZ 3.69Å; F141-F234 AromaticContact CD1-CE2 3.76Å; F141-F234 HydrophobicContact CD1-CE2 3.76Å; F141-F234 HydrophobicContact CD1-CZ 4.28Å; F141-F234 HydrophobicContact CD2-CE2 4.14Å; F141-F234 HydrophobicContact CD2-CZ 4.31Å; F141-F234 HydrophobicContact CE1-CE2 4.2Å; F141-F234 AromaticContact CG-CE2 3.73Å; F141-F234 HydrophobicContact CG-CE2 3.73Å; F141-F234 AromaticContact CG-CZ 3.86Å; F141-F234 HydrophobicContact CG-CZ 3.86Å
142R93.4Very high93Very high44 Ų4434.2 Ų34.217%0.16621%0.214CC..EExtended strand (participates in β ladder)trans-145.4168.5178.169.3-178.9-170.4-177.71.7111.9L150 Q151 Y181 D184 W186 N187 L226R142-L150 CarbonylContact O-C 3.59Å; R142-L150 WeakPolarHBondContact O-CA 3.29Å; R142-Q151 HydrophobicContact CG-CB 4.01Å; R142-Q151 VanDerWaalsContact CZ-OE1 3.3Å; R142-Q151 PolarHBondContact N-O 2.87Å; R142-Q151 PolarHBondContact O-N 2.69Å; R142-Y181 HydrophobicContact CG-CD1 4.23Å; R142-Y181 HydrophobicContact CG-CE1 3.87Å; R142-Y181 HydrophobicContact CG-CE2 4.41Å; R142-D184 PolarHBondContact NH1-O 3.48Å; R142-W186 PolarHBondContact NH1-O 3.5Å; R142-W186 PolarHBondContact NH2-O 3.3Å; R142-N187 PolarHBondContact NH2-O 3.31Å; R142-L226 VanDerWaalsContact C-CD1 3.49Å
143V92.1Very high93.1Very high47 Ų4735.4 Ų35.429%0.28522%0.22SC..EExtended strand (participates in β ladder)trans-95.5124.2160.6-1770000107.4S145 N149 L150 V220 L226V143-S145 PolarHBondContact O-N 3.38Å; V143-N149 WeakPolarHBondContact CA-O 3.22Å; V143-L150 HydrophobicContact CG2-CD2 4.24Å; V143-V220 HydrophobicContact CG2-CG2 4.45Å; V143-L226 HydrophobicContact CB-CD1 4.45Å; V143-L226 HydrophobicContact CG2-CD1 3.69Å; V143-L226 HydrophobicContact CG2-CD2 4.26Å; V143-L226 HydrophobicContact CG2-CG 4.07Å
144N90.5Very high93.1Very high4 Ų433.2 Ų33.22%0.02121%0.205CC..  trans-64.1132.3175.2-173.1-89.9000110.5S146 S147 H148 N149 Q151 N187N144-S146 VanDerWaalsContact C-N 3.27Å; N144-S146 PolarHBondContact O-N 2.85Å; N144-S146 WeakPolarHBondContact OD1-CA 3.46Å; N144-S146 WeakPolarHBondContact OD1-CB 3.43Å; N144-S146 PolarHBondContact OD1-N 3.19Å; N144-S147 VanDerWaalsContact CB-OG 3.24Å; N144-S147 WeakPolarHBondContact CB-OG 3.36Å; N144-S147 PolarHBondContact OD1-N 2.94Å; N144-S147 PolarHBondContact OD1-OG 3.37Å; N144-H148 WeakPolarHBondContact O-CA 3.45Å; N144-H148 PolarHBondContact O-N 3.5Å; N144-N149 PolarHBondContact N-O 3.32Å; N144-Q151 HydrophobicContact CB-CG 4.04Å; N144-Q151 PolarHBondContact ND2-NE2 3.47Å; N144-Q151 PolarHBondContact ND2-OE1 3.07Å; N144-N187 PolarHBondContact ND2-O 3.41Å
145S86.3Confident93.1Very high95 Ų9534.2 Ų34.266%0.66422%0.217SC*.THydrogen-bonded Turntrans-67.7-25.3-178.150.70000114.2V143 H148V143-S145 PolarHBondContact O-N 3.38Å; S145-H148 PolarHBondContact O-NE2 2.95Å
146S86.1Confident93.1Very high82 Ų8232.6 Ų32.657%0.57320%0.203SC*.THydrogen-bonded Turntrans-94.9-51.7-175.8-55.30000112.1N144 H148N144-S146 VanDerWaalsContact C-N 3.27Å; N144-S146 PolarHBondContact O-N 2.85Å; N144-S146 WeakPolarHBondContact OD1-CA 3.46Å; N144-S146 WeakPolarHBondContact OD1-CB 3.43Å; N144-S146 PolarHBondContact OD1-N 3.19Å; S146-H148 PolarHBondContact O-CD2 2.97Å
147S86.1Confident93.1Very high15 Ų1527.7 Ų27.711%0.10518%0.18CC..THydrogen-bonded Turntrans-80-28179.164.40000112.5N144 N149 R219N144-S147 VanDerWaalsContact CB-OG 3.24Å; N144-S147 WeakPolarHBondContact CB-OG 3.36Å; N144-S147 PolarHBondContact OD1-N 2.94Å; N144-S147 PolarHBondContact OD1-OG 3.37Å; S147-N149 PolarHBondContact O-N 2.88Å; S147-N149 PolarHBondContact O-OD1 3.26Å; S147-N149 PolarHBondContact OG-N 3.32Å; S147-R219 WeakPolarHBondContact O-CG 3.25Å; S147-R219 PolarHBondContact O-NE 3.25Å; S147-R219 VanDerWaalsContact O-NE 3.08Å
148H89.2Confident93.1Very high79 Ų7927.8 Ų27.837%0.36618%0.18SC..  trans63.822.2-168.9-52.8-96.2000114N144 S145 S146 R219 V220N144-H148 WeakPolarHBondContact O-CA 3.45Å; N144-H148 PolarHBondContact O-N 3.5Å; S145-H148 PolarHBondContact O-NE2 2.95Å; S146-H148 PolarHBondContact O-CD2 2.97Å; H148-R219 PolarHBondContact CD2-NH2 3.41Å; H148-V220 WeakPolarHBondContact O-CG2 3.29Å; H148-V220 PolarHBondContact O-N 2.92Å
149N90.8Very high93.1Very high7 Ų733.2 Ų33.24%0.03719%0.186CC..  trans-93.6156.1174.7-61.1-11.6000110.2V143 N144 S147 F211 Y216 G218 R219V143-N149 WeakPolarHBondContact CA-O 3.22Å; N144-N149 PolarHBondContact N-O 3.32Å; S147-N149 PolarHBondContact O-N 2.88Å; S147-N149 PolarHBondContact O-OD1 3.26Å; S147-N149 PolarHBondContact OG-N 3.32Å; N149-F211 WeakPolarHBondContact ND2-CE2 3.49Å; N149-F211 WeakPolarHBondContact ND2-CZ 3.48Å; N149-Y216 WeakPolarHBondContact ND2-CE1 3.47Å; N149-G218 PolarHBondContact OD1-O 2.76Å; N149-R219 WeakPolarHBondContact OD1-CA 3.46Å; N149-R219 WeakPolarHBondContact OD1-CG 3.38Å; N149-R219 PolarHBondContact OD1-N 2.91Å
150L92.8Very high93.1Very high20 Ų2034.2 Ų34.211%0.10519%0.19CC..EExtended strand (participates in β ladder)trans-66.7137.1168.8-72.1168.5000109.8R142 V143 D179 V220 L226 V233 F234R142-L150 CarbonylContact O-C 3.59Å; R142-L150 WeakPolarHBondContact O-CA 3.29Å; V143-L150 HydrophobicContact CG2-CD2 4.24Å; L150-D179 WeakPolarHBondContact O-CB 3.47Å; L150-V220 HydrophobicContact CD2-CG2 4.5Å; L150-V220 HydrophobicContact CG-CG2 4.07Å; L150-L226 HydrophobicContact CD2-CD2 4.17Å; L150-V233 HydrophobicContact CD1-CG2 4.49Å; L150-V233 WeakPolarHBondContact CD1-O 3.35Å; L150-V233 HydrophobicContact CD2-CG2 4.37Å; L150-F234 HydrophobicContact CB-CE1 3.93Å; L150-F234 HydrophobicContact CD1-CD1 3.92Å; L150-F234 HydrophobicContact CD1-CE1 3.87Å; L150-F234 HydrophobicContact CG-CE1 4.37Å
151Q94.9Very high93.1Very high0 Ų032.3 Ų32.30%018%0.176CC..EExtended strand (participates in β ladder)trans-127.3144174.1-65.8-172.8-57.500110.9F141 R142 N144 D179 L180 Y181 N187F141-Q151 CarbonylContact C-O 3.48Å; F141-Q151 WeakPolarHBondContact CA-O 3.48Å; F141-Q151 VanDerWaalsContact CB-O 3.25Å; F141-Q151 WeakPolarHBondContact CB-O 3.19Å; R142-Q151 HydrophobicContact CG-CB 4.01Å; R142-Q151 VanDerWaalsContact CZ-OE1 3.3Å; R142-Q151 PolarHBondContact N-O 2.87Å; R142-Q151 PolarHBondContact O-N 2.69Å; N144-Q151 HydrophobicContact CB-CG 4.04Å; N144-Q151 PolarHBondContact ND2-NE2 3.47Å; N144-Q151 PolarHBondContact ND2-OE1 3.07Å; Q151-D179 CarbonylContact C-O 3.55Å; Q151-D179 WeakPolarHBondContact CA-O 3.41Å; Q151-D179 HydrophobicContact CG-CB 3.86Å; Q151-D179 VanDerWaalsContact CG-OD2 3.31Å; Q151-D179 WeakPolarHBondContact CG-OD2 3.24Å; Q151-D179 PolarHBondContact NE2-OD2 3.32Å; Q151-L180 PolarHBondContact NE2-O 3.04Å; Q151-Y181 HydrophobicContact CB-CD1 3.65Å; Q151-Y181 HydrophobicContact CB-CE1 4.24Å; Q151-Y181 HydrophobicContact CB-CG 4.44Å; Q151-N187 PolarHBondContact NE2-O 3.45Å; Q151-N187 PolarHBondContact OE1-O 3.17Å
152I96.2Very high93.1Very high0 Ų034.1 Ų34.10%020%0.196CC..EExtended strand (participates in β ladder)trans-114.9144.3174.758.3-179.7000111.1V134 F141 T154 L157 T176 I178 D179 L180 Y181 F234V134-I152 HydrophobicContact CG1-CG2 4.02Å; F141-I152 HydrophobicContact CB-CG2 4.03Å; I152-T154 PolarHBondContact O-N 3.12Å; I152-L157 HydrophobicContact CD1-CD1 3.61Å; I152-L157 HydrophobicContact CD1-CD2 4.35Å; I152-L157 HydrophobicContact CG1-CD1 3.9Å; I152-T176 HydrophobicContact CD1-CG2 4.3Å; I152-I178 HydrophobicContact CD1-CB 4.07Å; I152-I178 HydrophobicContact CD1-CD1 4.26Å; I152-I178 HydrophobicContact CD1-CG2 4.18Å; I152-I178 HydrophobicContact CG1-CB 4.38Å; I152-I178 HydrophobicContact CG1-CG2 4.03Å; I152-I178 HydrophobicContact CG2-CG2 4.01Å; I152-D179 PolarHBondContact N-O 3.29Å; I152-L180 HydrophobicContact CD1-CD2 4.06Å; I152-L180 HydrophobicContact CG1-CD2 3.5Å; I152-Y181 VanDerWaalsContact C-CD1 3.46Å; I152-Y181 VanDerWaalsContact C-CE1 3.4Å; I152-Y181 VanDerWaalsContact O-CD1 3.28Å; I152-Y181 WeakPolarHBondContact O-CD1 3.45Å; I152-Y181 PolarHBondContact O-N 2.99Å; I152-F234 HydrophobicContact CG2-CE1 3.88Å; I152-F234 HydrophobicContact CG2-CE2 4.43Å; I152-F234 HydrophobicContact CG2-CZ 3.53Å
153L96.4Very high93.3Very high30 Ų3040.2 Ų40.216%0.15722%0.224CC..EExtended strand (participates in β ladder)trans-78.8119.5-172.6-176.865.7000110.8S140 G155 D156 L157 Y181 P182S140-L153 PolarHBondContact O-N 3.02Å; L153-G155 VanDerWaalsContact C-N 3.31Å; L153-G155 PolarHBondContact O-N 3.5Å; L153-D156 PolarHBondContact O-N 3.16Å; L153-L157 PolarHBondContact O-N 3.36Å; L153-Y181 HydrophobicContact CB-CD1 4.45Å; L153-Y181 HydrophobicContact CB-CE1 3.74Å; L153-Y181 HydrophobicContact CB-CE2 4.39Å; L153-Y181 HydrophobicContact CD1-CD2 3.9Å; L153-Y181 HydrophobicContact CD1-CE1 4.3Å; L153-Y181 HydrophobicContact CD1-CE2 3.54Å; L153-Y181 HydrophobicContact CD1-CG 4.43Å; L153-Y181 HydrophobicContact CG-CE2 4.49Å; L153-Y181 VanDerWaalsContact N-CE1 3.29Å; L153-P182 WeakPolarHBondContact CD1-O 3.23Å
154T95Very high93.4Very high0 Ų042.9 Ų42.90%023%0.228CC..Hα-helixtrans-60.6-37.2-177.654.30000113.1I152 D156 L157 L158 L180 Y181 P182 V189 Q192 V201I152-T154 PolarHBondContact O-N 3.12Å; T154-D156 VanDerWaalsContact C-N 3.28Å; T154-D156 PolarHBondContact O-N 2.94Å; T154-L157 PolarHBondContact O-N 3.22Å; T154-L157 VanDerWaalsContact O-N 3.15Å; T154-L158 WeakPolarHBondContact O-CG 3.38Å; T154-L158 PolarHBondContact O-N 2.91Å; T154-L180 HydrophobicContact CG2-CB 3.8Å; T154-L180 HydrophobicContact CG2-CD1 4.13Å; T154-L180 HydrophobicContact CG2-CD2 4.21Å; T154-L180 HydrophobicContact CG2-CG 4.25Å; T154-Y181 PolarHBondContact N-O 3.25Å; T154-Y181 PolarHBondContact OG1-O 3.33Å; T154-P182 WeakPolarHBondContact OG1-CA 3.45Å; T154-V189 HydrophobicContact CG2-CG2 3.83Å; T154-Q192 HydrophobicContact CG2-CB 4.07Å; T154-Q192 PolarHBondContact OG1-OE1 3.16Å; T154-V201 HydrophobicContact CG2-CG1 4.07Å
155G94.1Very high93.7Very high28 Ų2845.6 Ų45.629%0.28924%0.24SC..Hα-helixtrans-61.1-34.2-178.700000113.6L153 R159L153-G155 VanDerWaalsContact C-N 3.31Å; L153-G155 PolarHBondContact O-N 3.5Å; G155-R159 PolarHBondContact O-N 3.33Å
156D96.1Very high94.2Very high28 Ų2842.5 Ų42.515%0.1522%0.218CC..Hα-helixtrans-75-38.7175.9-68.8-22.1000111.1C139 S140 L153 T154 R159 F160C139-D156 HydrophobicContact CB-CB 3.77Å; S140-D156 VanDerWaalsContact CB-OD2 3.3Å; S140-D156 WeakPolarHBondContact CB-OD2 3.3Å; S140-D156 PolarHBondContact N-OD2 3.13Å; S140-D156 PolarHBondContact OG-OD2 3.24Å; L153-D156 PolarHBondContact O-N 3.16Å; T154-D156 VanDerWaalsContact C-N 3.28Å; T154-D156 PolarHBondContact O-N 2.94Å; D156-R159 WeakPolarHBondContact O-CB 3.42Å; D156-R159 PolarHBondContact O-N 3.04Å; D156-R159 IonicContact OD1-NH2 2.72Å; D156-F160 PolarHBondContact O-N 3.06Å
157L96.3Very high94.5Very high0 Ų048.2 Ų48.20%023%0.232CC..Hα-helixtrans-63.8-43.7175.4-58.2-179.9000111.8I96 T137 C139 I152 L153 T154 R159 F160 L161 L180 V201I96-L157 HydrophobicContact CD1-CD2 4.21Å; I96-L157 HydrophobicContact CG2-CD2 4.48Å; T137-L157 HydrophobicContact CG2-CD2 3.89Å; C139-L157 HydrophobicContact CB-CD2 3.72Å; C139-L157 HydrophobicContact CB-CG 4.32Å; I152-L157 HydrophobicContact CD1-CD1 3.61Å; I152-L157 HydrophobicContact CD1-CD2 4.35Å; I152-L157 HydrophobicContact CG1-CD1 3.9Å; L153-L157 PolarHBondContact O-N 3.36Å; T154-L157 PolarHBondContact O-N 3.22Å; T154-L157 VanDerWaalsContact O-N 3.15Å; L157-R159 VanDerWaalsContact C-N 3.29Å; L157-R159 PolarHBondContact O-N 3.44Å; L157-F160 WeakPolarHBondContact O-CB 3.43Å; L157-F160 PolarHBondContact O-N 3.29Å; L157-F160 VanDerWaalsContact O-N 3.12Å; L157-L161 VanDerWaalsContact O-CG 3.32Å; L157-L161 WeakPolarHBondContact O-CG 3.38Å; L157-L161 PolarHBondContact O-N 2.96Å; L157-L180 HydrophobicContact CD1-CD2 3.83Å; L157-V201 HydrophobicContact CB-CB 4.44Å; L157-V201 HydrophobicContact CB-CG1 4.26Å; L157-V201 HydrophobicContact CB-CG2 4.11Å; L157-V201 HydrophobicContact CD1-CG2 3.65Å
158L95.3Very high95Very high16 Ų1650.7 Ų50.78%0.08424%0.244CC..Hα-helixtrans-60.6-39.6175.6-70.7173.3000111.6T154 F160 L161 G162 Q192 M199 V201T154-L158 WeakPolarHBondContact O-CG 3.38Å; T154-L158 PolarHBondContact O-N 2.91Å; L158-F160 VanDerWaalsContact C-N 3.33Å; L158-L161 PolarHBondContact O-N 2.76Å; L158-G162 PolarHBondContact O-N 2.83Å; L158-Q192 HydrophobicContact CD1-CB 4.49Å; L158-Q192 HydrophobicContact CD1-CG 4.05Å; L158-M199 HydrophobicContact CD2-CB 4.11Å; L158-V201 HydrophobicContact CD2-CG1 4.12Å; L158-V201 HydrophobicContact CG-CG1 4.12Å
159R95.8Very high95.4Very high161 Ų16147 Ų4761%0.60823%0.228SC*.Hα-helixtrans-65.6-37.7175-165.5-174.7-46.9178.714112.2G155 D156 L157 K163G155-R159 PolarHBondContact O-N 3.33Å; D156-R159 WeakPolarHBondContact O-CB 3.42Å; D156-R159 PolarHBondContact O-N 3.04Å; D156-R159 IonicContact OD1-NH2 2.72Å; L157-R159 VanDerWaalsContact C-N 3.29Å; L157-R159 PolarHBondContact O-N 3.44Å; R159-K163 PolarHBondContact O-N 3.15Å
160F96.7Very high95.6Very high21 Ų2147.1 Ų47.19%0.09223%0.228CC..Hα-helixtrans-64.3-48.6173.8170.2-95.4000111.4Q94 V132 E136 T137 D156 L157 L158 G162 K163 R164Q94-F160 HydrophobicContact CG-CE1 4.32Å; V132-F160 HydrophobicContact CB-CZ 4.29Å; V132-F160 HydrophobicContact CG1-CZ 4.14Å; V132-F160 HydrophobicContact CG2-CE1 3.91Å; V132-F160 HydrophobicContact CG2-CZ 3.85Å; E136-F160 WeakPolarHBondContact O-CE2 3.34Å; T137-F160 HydrophobicContact CG2-CD1 4.27Å; T137-F160 HydrophobicContact CG2-CE1 4.24Å; T137-F160 HydrophobicContact CG2-CG 4.43Å; T137-F160 HydrophobicContact CG2-CZ 4.35Å; D156-F160 PolarHBondContact O-N 3.06Å; L157-F160 WeakPolarHBondContact O-CB 3.43Å; L157-F160 PolarHBondContact O-N 3.29Å; L157-F160 VanDerWaalsContact O-N 3.12Å; L158-F160 VanDerWaalsContact C-N 3.33Å; F160-G162 VanDerWaalsContact C-N 3.29Å; F160-G162 PolarHBondContact O-N 3.28Å; F160-K163 PolarHBondContact O-N 3.28Å; F160-K163 VanDerWaalsContact O-N 3.11Å; F160-R164 HydrophobicContact CZ-CG 4.42Å; F160-R164 PolarHBondContact O-N 3.11Å
161L96.7Very high95.8Very high0 Ų046.2 Ų46.20%022%0.223CC..Hα-helixtrans-59.7-39.4177.4-66.6176000111.7Q94 L157 L158 K163 R164 K165 I172 M199 G200 V201Q94-L161 HydrophobicContact CB-CD2 3.66Å; Q94-L161 HydrophobicContact CG-CD2 3.72Å; L157-L161 VanDerWaalsContact O-CG 3.32Å; L157-L161 WeakPolarHBondContact O-CG 3.38Å; L157-L161 PolarHBondContact O-N 2.96Å; L158-L161 PolarHBondContact O-N 2.76Å; L161-K163 PolarHBondContact O-N 3.31Å; L161-R164 CarbonylContact O-C 3.57Å; L161-R164 PolarHBondContact O-N 3.3Å; L161-K165 PolarHBondContact O-N 3.48Å; L161-I172 HydrophobicContact CB-CD1 4.43Å; L161-I172 HydrophobicContact CB-CG2 4.22Å; L161-I172 HydrophobicContact CD2-CD1 3.88Å; L161-I172 HydrophobicContact CD2-CG1 4.17Å; L161-M199 HydrophobicContact CB-SD 4.3Å; L161-G200 WeakPolarHBondContact CD1-O 3.4Å; L161-V201 HydrophobicContact CD1-CB 4.27Å
162G95.6Very high95.9Very high40 Ų4046.2 Ų46.241%0.41222%0.223SC..Hα-helixtrans-60.6-28.8177.300000114.1L158 F160 M199L158-G162 PolarHBondContact O-N 2.83Å; F160-G162 VanDerWaalsContact C-N 3.29Å; F160-G162 PolarHBondContact O-N 3.28Å; G162-M199 WeakPolarHBondContact CA-SD 3.36Å; G162-M199 PolarHBondContact N-SD 3.42Å
163K95.6Very high95.9Very high172 Ų17246.2 Ų46.275%0.74822%0.223SC*.Hα-helixtrans-79.8-19.7174.6-64.8175.5-176.7178.80113.3R159 F160 L161R159-K163 PolarHBondContact O-N 3.15Å; F160-K163 PolarHBondContact O-N 3.28Å; F160-K163 VanDerWaalsContact O-N 3.11Å; L161-K163 PolarHBondContact O-N 3.31Å
164R95.6Very high95.9Very high102 Ų10244.8 Ų44.839%0.38522%0.215SC..Hα-helixtrans-106.6-13.6-176.7-62.8-167.890.2126.2-1.8113.7F160 L161 P166F160-R164 HydrophobicContact CZ-CG 4.42Å; F160-R164 PolarHBondContact O-N 3.11Å; L161-R164 CarbonylContact O-C 3.57Å; L161-R164 PolarHBondContact O-N 3.3Å; R164-P166 WeakPolarHBondContact O-CD 3.48Å; R164-P166 VanDerWaalsContact O-N 3.11Å
165K95.8Very high95.9Very high61 Ų6144.8 Ų44.827%0.26522%0.215SC..  trans-52.6115.7179.9-171.6179.4179.2-174.10109.8L161 A169 I172 D197L161-K165 PolarHBondContact O-N 3.48Å; K165-A169 HydrophobicContact CD-CB 4.43Å; K165-A169 WeakPolarHBondContact CE-O 3.19Å; K165-A169 HydrophobicContact CG-CB 3.77Å; K165-I172 HydrophobicContact CB-CG2 3.86Å; K165-I172 HydrophobicContact CD-CG2 4.09Å; K165-I172 HydrophobicContact CG-CB 4.24Å; K165-I172 HydrophobicContact CG-CG2 3.75Å; K165-D197 PolarHBondContact NZ-O 3.02Å
166P96.6Very high95.9Very high31 Ų3143.4 Ų43.420%0.20120%0.202CC..  trans-60.8155.7175-27.439.4000111.7Y92 L129 R164 D168 A169Y92-P166 HydrophobicContact CD1-CG 3.84Å; Y92-P166 HydrophobicContact CD2-CB 4.13Å; Y92-P166 HydrophobicContact CD2-CG 3.74Å; Y92-P166 HydrophobicContact CE1-CB 4.33Å; Y92-P166 HydrophobicContact CE1-CG 3.73Å; Y92-P166 HydrophobicContact CE2-CB 3.58Å; Y92-P166 HydrophobicContact CE2-CG 3.61Å; Y92-P166 HydrophobicContact CG-CG 3.83Å; L129-P166 HydrophobicContact CD2-CG 4.48Å; R164-P166 WeakPolarHBondContact O-CD 3.48Å; R164-P166 VanDerWaalsContact O-N 3.11Å; P166-D168 VanDerWaalsContact C-N 3.29Å; P166-D168 WeakPolarHBondContact CB-OD1 3.46Å; P166-D168 PolarHBondContact O-N 2.96Å; P166-A169 HydrophobicContact CB-CB 4.31Å; P166-A169 WeakPolarHBondContact O-CB 3.35Å; P166-A169 PolarHBondContact O-N 3.24Å
167K94.2Very high95.8Very high202 Ų20242.4 Ų42.488%0.87820%0.196SC*.THydrogen-bonded Turntrans-68.6-31.6-175.1-69.7-175.8179.2178.70112.6H88 A169H88-K167 PolarHBondContact CD2-O 2.84Å; H88-K167 VanDerWaalsContact CD2-O 3.23Å; H88-K167 PolarHBondContact NE2-O 3.45Å; K167-A169 VanDerWaalsContact C-N 3.29Å
168D95.6Very high95.6Very high66 Ų6642.6 Ų42.635%0.35320%0.197SC..THydrogen-bonded Turntrans-89.26.1177.765.2-37.5000113.3G87 H88 Y92 P166 F170G87-D168 WeakPolarHBondContact O-CA 3.25Å; G87-D168 WeakPolarHBondContact O-CB 3.32Å; H88-D168 WeakPolarHBondContact CA-O 3.44Å; Y92-D168 PolarHBondContact OH-OD1 2.87Å; Y92-D168 PolarHBondContact OH-OD2 3Å; P166-D168 VanDerWaalsContact C-N 3.29Å; P166-D168 WeakPolarHBondContact CB-OD1 3.46Å; P166-D168 PolarHBondContact O-N 2.96Å; D168-F170 PolarHBondContact O-N 3.21Å
169A96.6Very high95.6Very high2 Ų242 Ų422%0.01719%0.194CC..EExtended strand (participates in β ladder)trans-71.2120.4178.400000110.7T90 Y92 K165 P166 K167 C171T90-A169 CarbonylContact O-C 3.53Å; T90-A169 WeakPolarHBondContact O-CA 3.3Å; Y92-A169 HydrophobicContact CD2-CB 3.45Å; Y92-A169 VanDerWaalsContact CD2-CB 3.45Å; Y92-A169 HydrophobicContact CE2-CB 3.74Å; K165-A169 HydrophobicContact CD-CB 4.43Å; K165-A169 WeakPolarHBondContact CE-O 3.19Å; K165-A169 HydrophobicContact CG-CB 3.77Å; P166-A169 HydrophobicContact CB-CB 4.31Å; P166-A169 WeakPolarHBondContact O-CB 3.35Å; P166-A169 PolarHBondContact O-N 3.24Å; K167-A169 VanDerWaalsContact C-N 3.29Å; A169-C171 VanDerWaalsContact C-N 3.33Å
170F96.3Very high95.5Very high10 Ų1034.4 Ų34.44%0.04417%0.165CC..EExtended strand (participates in β ladder)trans-56.8-54.3158.2177.7-112.1000109.1K82 P84 H88 T90 I91 L124 D168 M261 F262K82-F170 HydrophobicContact CB-CE2 4.06Å; K82-F170 HydrophobicContact CB-CZ 4.35Å; P84-F170 HydrophobicContact CB-CD2 4.07Å; P84-F170 HydrophobicContact CB-CE2 4.37Å; P84-F170 HydrophobicContact CG-CD2 3.78Å; P84-F170 HydrophobicContact CG-CE1 4.47Å; P84-F170 HydrophobicContact CG-CE2 3.69Å; P84-F170 HydrophobicContact CG-CG 4.22Å; P84-F170 HydrophobicContact CG-CZ 4.06Å; H88-F170 WeakPolarHBondContact O-CB 3.29Å; T90-F170 PolarHBondContact O-N 3.15Å; I91-F170 HydrophobicContact CG1-CD1 4.3Å; L124-F170 HydrophobicContact CD2-CB 4.4Å; L124-F170 HydrophobicContact CD2-CD1 3.88Å; L124-F170 HydrophobicContact CD2-CE1 4.45Å; L124-F170 HydrophobicContact CD2-CG 4.16Å; D168-F170 PolarHBondContact O-N 3.21Å; F170-M261 HydrophobicContact CE1-CB 3.88Å; F170-M261 HydrophobicContact CZ-CB 4.39Å; F170-F262 HydrophobicContact CD1-CZ 4.38Å; F170-F262 HydrophobicContact CE1-CD1 4.2Å; F170-F262 AromaticContact CE1-CD2 3.95Å; F170-F262 HydrophobicContact CE1-CD2 3.95Å; F170-F262 AromaticContact CE1-CE1 3.91Å; F170-F262 HydrophobicContact CE1-CE1 3.91Å; F170-F262 AromaticContact CE1-CE2 3.6Å; F170-F262 HydrophobicContact CE1-CE2 3.6Å; F170-F262 HydrophobicContact CE1-CG 4.23Å; F170-F262 AromaticContact CE1-CZ 3.59Å; F170-F262 HydrophobicContact CE1-CZ 3.59Å; F170-F262 AromaticContact CZ-CD1 3.75Å; F170-F262 HydrophobicContact CZ-CD1 3.75Å; F170-F262 HydrophobicContact CZ-CD2 4.14Å; F170-F262 AromaticContact CZ-CE1 3.77Å; F170-F262 HydrophobicContact CZ-CE1 3.77Å; F170-F262 HydrophobicContact CZ-CE2 4.13Å; F170-F262 AromaticContact CZ-CG 3.95Å; F170-F262 HydrophobicContact CZ-CG 3.95Å; F170-F262 AromaticContact CZ-CZ 3.95Å; F170-F262 HydrophobicContact CZ-CZ 3.95Å
171C96.5Very high95.3Very high0 Ų033.7 Ų33.70%016%0.162CC..EExtended strand (participates in β ladder)trans-149.1165172.667.50000112Y92 A169 G198 M261Y92-C171 PolarHBondContact N-O 2.64Å; A169-C171 VanDerWaalsContact C-N 3.33Å; C171-G198 CarbonylContact C-O 3.56Å; C171-G198 WeakPolarHBondContact CA-O 3.46Å; C171-G198 VanDerWaalsContact CB-O 3.29Å; C171-G198 WeakPolarHBondContact CB-O 3.31Å; C171-M261 HydrophobicContact CB-CB 4.06Å; C171-M261 HydrophobicContact CB-CG 3.7Å; C171-M261 HydrophobicContact CB-SD 3.84Å
172I97.2Very high95Very high0 Ų035.2 Ų35.20%017%0.172CC..EExtended strand (participates in β ladder)trans-123.7131.6168.6-176.1172.8000109.1Y92 Q94 L129 L161 K165 G198 M199 G200Y92-I172 CarbonylContact O-C 3.52Å; Y92-I172 WeakPolarHBondContact O-CA 3.27Å; Q94-I172 HydrophobicContact CB-CD1 4.41Å; L129-I172 HydrophobicContact CD1-CD1 3.64Å; L129-I172 HydrophobicContact CD1-CG1 4.42Å; L161-I172 HydrophobicContact CB-CD1 4.43Å; L161-I172 HydrophobicContact CB-CG2 4.22Å; L161-I172 HydrophobicContact CD2-CD1 3.88Å; L161-I172 HydrophobicContact CD2-CG1 4.17Å; K165-I172 HydrophobicContact CB-CG2 3.86Å; K165-I172 HydrophobicContact CD-CG2 4.09Å; K165-I172 HydrophobicContact CG-CB 4.24Å; K165-I172 HydrophobicContact CG-CG2 3.75Å; I172-G198 PolarHBondContact N-O 2.63Å; I172-M199 HydrophobicContact CG2-CB 4.33Å; I172-M199 HydrophobicContact CG2-CG 3.83Å; I172-M199 CarbonylContact O-C 3.57Å; I172-M199 VanDerWaalsContact O-CA 3.28Å; I172-M199 WeakPolarHBondContact O-CA 3.49Å; I172-G200 PolarHBondContact O-N 3.03Å
173V96.3Very high94.7Very high0 Ų038.7 Ų38.70%018%0.176CC..EExtended strand (participates in β ladder)trans-120.1124177.4-65.40000110.4I91 Y92 I93 Q94 G200 F202I91-V173 HydrophobicContact CG2-CG2 4.45Å; Y92-V173 PolarHBondContact O-N 3.32Å; I93-V173 CarbonylContact C-O 3.57Å; I93-V173 WeakPolarHBondContact CA-O 3.37Å; I93-V173 HydrophobicContact CB-CG2 4.36Å; I93-V173 HydrophobicContact CG1-CG2 3.81Å; Q94-V173 PolarHBondContact N-O 3.49Å; V173-G200 CarbonylContact C-O 3.48Å; V173-G200 WeakPolarHBondContact CA-O 3.47Å; V173-F202 HydrophobicContact CB-CE2 3.64Å; V173-F202 HydrophobicContact CB-CZ 4.19Å; V173-F202 HydrophobicContact CG1-CE2 3.65Å; V173-F202 HydrophobicContact CG1-CZ 3.8Å
174G96.1Very high94.1Very high0 Ų036.6 Ų36.60%017%0.173CC..EExtended strand (participates in β ladder)trans-84.6133.3170.300000110.5Q94 G200 V201 F202Q94-G174 CarbonylContact O-C 3.55Å; Q94-G174 VanDerWaalsContact O-CA 3.29Å; Q94-G174 WeakPolarHBondContact O-CA 3.22Å; G174-G200 PolarHBondContact N-O 2.99Å; G174-V201 CarbonylContact O-C 3.59Å; G174-V201 VanDerWaalsContact O-CA 3.28Å; G174-V201 WeakPolarHBondContact O-CA 3.19Å; G174-F202 PolarHBondContact O-N 3.26Å
175I95.8Very high93.5Very high0 Ų036.4 Ų36.40%019%0.187CC..EExtended strand (participates in β ladder)trans-120.3142.7172.859.6169.1000110.2I93 Q94 I96 F99 V110 L113 F202 F204I93-I175 HydrophobicContact CG2-CD1 3.65Å; I93-I175 HydrophobicContact CG2-CG1 3.8Å; I93-I175 HydrophobicContact CG2-CG2 4.33Å; Q94-I175 PolarHBondContact O-N 3.22Å; I96-I175 PolarHBondContact N-O 2.81Å; F99-I175 HydrophobicContact CE1-CD1 4.01Å; F99-I175 HydrophobicContact CE1-CG1 4.32Å; F99-I175 HydrophobicContact CE2-CG1 4.38Å; F99-I175 HydrophobicContact CZ-CB 3.9Å; F99-I175 HydrophobicContact CZ-CD1 3.81Å; F99-I175 HydrophobicContact CZ-CG1 3.64Å; V110-I175 HydrophobicContact CG1-CD1 4.22Å; V110-I175 HydrophobicContact CG2-CD1 4.42Å; L113-I175 HydrophobicContact CD1-CD1 4.21Å; I175-F202 WeakPolarHBondContact CA-O 3.32Å; I175-F204 HydrophobicContact CB-CE2 3.96Å; I175-F204 HydrophobicContact CB-CZ 4.23Å; I175-F204 HydrophobicContact CD1-CE2 4.32Å; I175-F204 HydrophobicContact CG2-CE2 4.18Å; I175-F204 HydrophobicContact CG2-CZ 3.93Å
176T94.5Very high92.7Very high0 Ų039.8 Ų39.80%020%0.198CC..EExtended strand (participates in β ladder)trans-147.1156.5176.7-170.10000113I96 F99 I152 I178 L180 F202 S203 F204I96-T176 VanDerWaalsContact O-CB 3.31Å; I96-T176 WeakPolarHBondContact O-CB 3.35Å; I96-T176 PolarHBondContact O-OG1 3.25Å; F99-T176 VanDerWaalsContact CZ-CA 3.47Å; I152-T176 HydrophobicContact CD1-CG2 4.3Å; T176-I178 VanDerWaalsContact C-N 3.34Å; T176-I178 HydrophobicContact CG2-CB 4.46Å; T176-I178 VanDerWaalsContact CG2-O 3.27Å; T176-I178 WeakPolarHBondContact CG2-O 3.28Å; T176-I178 PolarHBondContact OG1-N 3.14Å; T176-I178 VanDerWaalsContact OG1-N 3.17Å; T176-L180 HydrophobicContact CG2-CD2 4.02Å; T176-L180 HydrophobicContact CG2-CG 4.36Å; T176-F202 PolarHBondContact N-O 2.83Å; T176-S203 VanDerWaalsContact O-CA 3.26Å; T176-S203 WeakPolarHBondContact O-CA 3.4Å; T176-F204 PolarHBondContact O-N 2.77Å
177M92.9Very high91.9Very high6 Ų643 Ų433%0.0321%0.214CC..SBendtrans-94.19.4167-71.4-67.5-179.500112.7F99 Y109 F204 A205 Y237 T239 P240 L246F99-M177 HydrophobicContact CB-CG 4.21Å; F99-M177 HydrophobicContact CD1-CE 3.47Å; F99-M177 VanDerWaalsContact CD1-CE 3.47Å; F99-M177 HydrophobicContact CD1-CG 3.56Å; F99-M177 HydrophobicContact CD1-SD 4.29Å; F99-M177 HydrophobicContact CD2-CG 4.15Å; F99-M177 HydrophobicContact CE1-CE 3.86Å; F99-M177 HydrophobicContact CE1-CG 3.93Å; F99-M177 HydrophobicContact CE1-SD 4.48Å; F99-M177 HydrophobicContact CE2-CG 4.46Å; F99-M177 HydrophobicContact CG-CE 4.37Å; F99-M177 HydrophobicContact CG-CG 3.67Å; F99-M177 HydrophobicContact CZ-CG 4.35Å; Y109-M177 HydrophobicContact CD1-CE 4.37Å; Y109-M177 HydrophobicContact CE1-CE 3.57Å; M177-F204 HydrophobicContact CE-CB 4.04Å; M177-F204 HydrophobicContact CE-CD2 3.99Å; M177-F204 HydrophobicContact SD-CB 3.71Å; M177-F204 HydrophobicContact SD-CD2 4.38Å; M177-A205 VanDerWaalsContact O-CB 3.24Å; M177-A205 WeakPolarHBondContact O-CB 3.23Å; M177-Y237 HydrophobicContact CB-CE2 4.36Å; M177-T239 HydrophobicContact CB-CG2 4Å; M177-T239 HydrophobicContact CG-CG2 4.4Å; M177-P240 HydrophobicContact CE-CG 4.4Å; M177-P240 HydrophobicContact SD-CG 3.6Å; M177-L246 HydrophobicContact CE-CD2 4.09Å
178I93.1Very high91.4Very high5 Ų535.8 Ų35.83%0.02618%0.182CC..SBendtrans-101.6137.4178.8-56.4165.8000109.2V134 I152 T176 S203 F234 Y237V134-I178 HydrophobicContact CG2-CD1 3.31Å; I152-I178 HydrophobicContact CD1-CB 4.07Å; I152-I178 HydrophobicContact CD1-CD1 4.26Å; I152-I178 HydrophobicContact CD1-CG2 4.18Å; I152-I178 HydrophobicContact CG1-CB 4.38Å; I152-I178 HydrophobicContact CG1-CG2 4.03Å; I152-I178 HydrophobicContact CG2-CG2 4.01Å; T176-I178 VanDerWaalsContact C-N 3.34Å; T176-I178 HydrophobicContact CG2-CB 4.46Å; T176-I178 VanDerWaalsContact CG2-O 3.27Å; T176-I178 WeakPolarHBondContact CG2-O 3.28Å; T176-I178 PolarHBondContact OG1-N 3.14Å; T176-I178 VanDerWaalsContact OG1-N 3.17Å; I178-S203 VanDerWaalsContact C-OG 3.29Å; I178-S203 WeakPolarHBondContact O-CB 3.49Å; I178-S203 PolarHBondContact O-OG 3.24Å; I178-F234 HydrophobicContact CD1-CD1 3.8Å; I178-F234 HydrophobicContact CD1-CE1 4Å; I178-F234 HydrophobicContact CG2-CE1 3.99Å; I178-Y237 HydrophobicContact CD1-CD1 4.33Å; I178-Y237 HydrophobicContact CD1-CE1 3.67Å; I178-Y237 HydrophobicContact CD1-CE2 4.2Å; I178-Y237 HydrophobicContact CG1-CD1 4.43Å; I178-Y237 HydrophobicContact CG1-CD2 4.08Å; I178-Y237 HydrophobicContact CG1-CE1 3.91Å; I178-Y237 HydrophobicContact CG1-CE2 3.5Å; I178-Y237 VanDerWaalsContact CG1-CE2 3.5Å
179D93.6Very high90.6Very high4 Ų434 Ų342%0.02117%0.174CC..EExtended strand (participates in β ladder)trans-61.5148.3-179.5-174.718.9000111.8L150 Q151 I152 A205 R206 F211L150-D179 WeakPolarHBondContact O-CB 3.47Å; Q151-D179 CarbonylContact C-O 3.55Å; Q151-D179 WeakPolarHBondContact CA-O 3.41Å; Q151-D179 HydrophobicContact CG-CB 3.86Å; Q151-D179 VanDerWaalsContact CG-OD2 3.31Å; Q151-D179 WeakPolarHBondContact CG-OD2 3.24Å; Q151-D179 PolarHBondContact NE2-OD2 3.32Å; I152-D179 PolarHBondContact N-O 3.29Å; D179-A205 HydrophobicContact CB-CB 4.15Å; D179-R206 IonicContact OD1-CZ 3.66Å; D179-R206 IonicContact OD1-NE 3.91Å; D179-R206 PolarHBondContact OD1-NE 3.31Å; D179-R206 IonicContact OD1-NH2 2.78Å; D179-R206 PolarHBondContact OD1-NH2 3.23Å; D179-R206 IonicContact OD2-CZ 2.82Å; D179-R206 IonicContact OD2-NE 3.74Å; D179-R206 PolarHBondContact OD2-NE 3.33Å; D179-R206 IonicContact OD2-NH2 3.69Å; D179-R206 PolarHBondContact OD2-NH2 2.9Å; D179-F211 HydrophobicContact CB-CZ 4.45Å
180L94.1Very high89.8Confident0 Ų035.2 Ų35.20%018%0.179CC..EExtended strand (participates in β ladder)trans-115.8149.4-172.5-65.3176.5000111.8Q151 I152 T154 L157 T176 F188 V189 V201Q151-L180 PolarHBondContact NE2-O 3.04Å; I152-L180 HydrophobicContact CD1-CD2 4.06Å; I152-L180 HydrophobicContact CG1-CD2 3.5Å; T154-L180 HydrophobicContact CG2-CB 3.8Å; T154-L180 HydrophobicContact CG2-CD1 4.13Å; T154-L180 HydrophobicContact CG2-CD2 4.21Å; T154-L180 HydrophobicContact CG2-CG 4.25Å; L157-L180 HydrophobicContact CD1-CD2 3.83Å; T176-L180 HydrophobicContact CG2-CD2 4.02Å; T176-L180 HydrophobicContact CG2-CG 4.36Å; L180-F188 WeakPolarHBondContact O-CA 3.25Å; L180-F188 WeakPolarHBondContact O-CB 3.48Å; L180-V189 HydrophobicContact CB-CG2 4.06Å; L180-V189 PolarHBondContact O-N 3.13Å; L180-V189 VanDerWaalsContact O-N 3.13Å; L180-V201 HydrophobicContact CD1-CG2 4.4Å
181Y93.7Very high89.2Confident7 Ų735.3 Ų35.33%0.02718%0.183CC..EExtended strand (participates in β ladder)trans-139.7145.8169.175.2-70.9000111.6R142 Q151 I152 L153 T154R142-Y181 HydrophobicContact CG-CD1 4.23Å; R142-Y181 HydrophobicContact CG-CE1 3.87Å; R142-Y181 HydrophobicContact CG-CE2 4.41Å; Q151-Y181 HydrophobicContact CB-CD1 3.65Å; Q151-Y181 HydrophobicContact CB-CE1 4.24Å; Q151-Y181 HydrophobicContact CB-CG 4.44Å; I152-Y181 VanDerWaalsContact C-CD1 3.46Å; I152-Y181 VanDerWaalsContact C-CE1 3.4Å; I152-Y181 VanDerWaalsContact O-CD1 3.28Å; I152-Y181 WeakPolarHBondContact O-CD1 3.45Å; I152-Y181 PolarHBondContact O-N 2.99Å; L153-Y181 HydrophobicContact CB-CD1 4.45Å; L153-Y181 HydrophobicContact CB-CE1 3.74Å; L153-Y181 HydrophobicContact CB-CE2 4.39Å; L153-Y181 HydrophobicContact CD1-CD2 3.9Å; L153-Y181 HydrophobicContact CD1-CE1 4.3Å; L153-Y181 HydrophobicContact CD1-CE2 3.54Å; L153-Y181 HydrophobicContact CD1-CG 4.43Å; L153-Y181 HydrophobicContact CG-CE2 4.49Å; L153-Y181 VanDerWaalsContact N-CE1 3.29Å; T154-Y181 PolarHBondContact N-O 3.25Å; T154-Y181 PolarHBondContact OG1-O 3.33Å
182P89.2Confident88.6Confident31 Ų3138.4 Ų38.420%0.20120%0.197CC..SBendtrans-90.2-31.5-175.634.4-35.2000113.8L153 T154 W186 V189L153-P182 WeakPolarHBondContact CD1-O 3.23Å; T154-P182 WeakPolarHBondContact OG1-CA 3.45Å; P182-W186 HydrophobicContact CG-CB 3.6Å; P182-W186 HydrophobicContact CG-CD2 4.04Å; P182-W186 HydrophobicContact CG-CE3 4.18Å; P182-W186 HydrophobicContact CG-CG 3.8Å; P182-V189 HydrophobicContact CB-CG1 4.25Å; P182-V189 HydrophobicContact CG-CG1 3.78Å
183K88.7Confident87.9Confident113 Ų11339.9 Ų39.949%0.49121%0.209SC..SBendtrans-164.1165.4176.362.5-176.3175.8-175.90110.4S185 W186K183-S185 WeakPolarHBondContact CE-OG 3.3Å; K183-S185 PolarHBondContact O-N 2.9Å; K183-S185 VanDerWaalsContact O-N 3.13Å; K183-W186 HydrophobicContact CG-CB 4.41Å; K183-W186 HydrophobicContact CG-CG 4.1Å; K183-W186 PolarHBondContact O-N 3.32Å
184D84.5Confident87.3Confident128 Ų12841 Ų4168%0.68422%0.217SC*.THydrogen-bonded Turntrans-57.8-33.9-171.7-67.4-26.2000114.3R142 W186R142-D184 PolarHBondContact NH1-O 3.48Å; D184-W186 VanDerWaalsContact C-N 3.28Å; D184-W186 PolarHBondContact O-N 2.85Å
185S82.7Confident86.4Confident98 Ų9844.5 Ų44.569%0.68524%0.236SC*.THydrogen-bonded Turntrans-78.6-3.6-179.259.50000115.4K183K183-S185 WeakPolarHBondContact CE-OG 3.3Å; K183-S185 PolarHBondContact O-N 2.9Å; K183-S185 VanDerWaalsContact O-N 3.13Å
186W79Confident85.3Confident132 Ų13248.4 Ų48.450%0.526%0.263SS..  trans-105.9148.6-178.8-79.753.9000110.8R142 P182 K183 D184R142-W186 PolarHBondContact NH1-O 3.5Å; R142-W186 PolarHBondContact NH2-O 3.3Å; P182-W186 HydrophobicContact CG-CB 3.6Å; P182-W186 HydrophobicContact CG-CD2 4.04Å; P182-W186 HydrophobicContact CG-CE3 4.18Å; P182-W186 HydrophobicContact CG-CG 3.8Å; K183-W186 HydrophobicContact CG-CB 4.41Å; K183-W186 HydrophobicContact CG-CG 4.1Å; K183-W186 PolarHBondContact O-N 3.32Å; D184-W186 VanDerWaalsContact C-N 3.28Å; D184-W186 PolarHBondContact O-N 2.85Å
187N78.8Confident84.7Confident99 Ų9952.3 Ų52.353%0.52928%0.284SS..  trans-72.6-53.9178.5-74.1-31.2000111.6R142 N144 Q151R142-N187 PolarHBondContact NH2-O 3.31Å; N144-N187 PolarHBondContact ND2-O 3.41Å; Q151-N187 PolarHBondContact NE2-O 3.45Å; Q151-N187 PolarHBondContact OE1-O 3.17Å
188F83.6Confident84.5Confident50 Ų5052 Ų5222%0.21928%0.283CS..  trans-166.6173179.868.8-84.7000111.6L180 F190 R206L180-F188 WeakPolarHBondContact O-CA 3.25Å; L180-F188 WeakPolarHBondContact O-CB 3.48Å; F188-F190 HydrophobicContact CE2-CD2 4.16Å; F188-F190 AromaticContact CE2-CE2 3.79Å; F188-F190 HydrophobicContact CE2-CE2 3.79Å; F188-F190 HydrophobicContact CE2-CZ 4.06Å; F188-R206 VanDerWaalsContact CD2-CZ 3.45Å; F188-R206 VanDerWaalsContact CE2-CD 3.48Å
189V79.4Confident84.5Confident28 Ų2852.6 Ų52.617%0.1729%0.285CS..BIsolated β-bridgetrans-137.3152.3161-71.10000109T154 L180 P182 G191T154-V189 HydrophobicContact CG2-CG2 3.83Å; L180-V189 HydrophobicContact CB-CG2 4.06Å; L180-V189 PolarHBondContact O-N 3.13Å; L180-V189 VanDerWaalsContact O-N 3.13Å; P182-V189 HydrophobicContact CB-CG1 4.25Å; P182-V189 HydrophobicContact CG-CG1 3.78Å; V189-G191 WeakPolarHBondContact CB-O 3.14Å; V189-G191 WeakPolarHBondContact CG2-O 3.38Å
190F81.1Confident84.5Confident28 Ų2852.4 Ų52.412%0.12328%0.284CS..SBendtrans-71.7-28.3166.9-70-79.6000111.2F188 F202 S203 R206 Y207F188-F190 HydrophobicContact CE2-CD2 4.16Å; F188-F190 AromaticContact CE2-CE2 3.79Å; F188-F190 HydrophobicContact CE2-CE2 3.79Å; F188-F190 HydrophobicContact CE2-CZ 4.06Å; F190-F202 CarbonylContact O-C 3.44Å; F190-F202 WeakPolarHBondContact O-CA 3.47Å; F190-S203 PolarHBondContact O-N 2.75Å; F190-R206 HydrophobicContact CD1-CB 4.11Å; F190-R206 HydrophobicContact CE1-CB 3.56Å; F190-R206 HydrophobicContact CZ-CB 4.42Å; F190-Y207 HydrophobicContact CD1-CD1 4.43Å; F190-Y207 AromaticContact CD1-CE1 3.58Å; F190-Y207 HydrophobicContact CD1-CE1 3.58Å; F190-Y207 AromaticContact CD1-CZ 3.62Å; F190-Y207 WeakPolarHBondContact CD1-OH 3.33Å; F190-Y207 HydrophobicContact CE1-CD1 4.03Å; F190-Y207 AromaticContact CE1-CE1 3.4Å; F190-Y207 HydrophobicContact CE1-CE1 3.4Å; F190-Y207 AromaticContact CE1-CZ 3.96Å; F190-Y207 HydrophobicContact CZ-CE1 4.3Å
191G82.8Confident84.4Confident13 Ų1352.4 Ų52.413%0.13428%0.284CS..EExtended strand (participates in β ladder)trans-167.5165.5-176.900000113V189 V201V189-G191 WeakPolarHBondContact CB-O 3.14Å; V189-G191 WeakPolarHBondContact CG2-O 3.38Å; G191-V201 CarbonylContact C-O 3.51Å; G191-V201 WeakPolarHBondContact CA-O 3.44Å
192Q83.6Confident84.3Confident64 Ų6452.1 Ų52.130%0.29928%0.283SS..EExtended strand (participates in β ladder)trans-145.6139.6169.8-172.5175.6-31.600110.3T154 L158 G200 V201T154-Q192 HydrophobicContact CG2-CB 4.07Å; T154-Q192 PolarHBondContact OG1-OE1 3.16Å; L158-Q192 HydrophobicContact CD1-CB 4.49Å; L158-Q192 HydrophobicContact CD1-CG 4.05Å; Q192-G200 CarbonylContact O-C 3.6Å; Q192-G200 WeakPolarHBondContact O-CA 3.44Å; Q192-V201 PolarHBondContact N-O 2.74Å; Q192-V201 PolarHBondContact O-N 3.36Å
193A82.7Confident84.5Confident31 Ų3150.7 Ų50.726%0.25627%0.274SS..EExtended strand (participates in β ladder)trans-125.4143.4-177.900000112.5L195 M199 M261A193-L195 HydrophobicContact CB-CD2 3.73Å; A193-M199 CarbonylContact C-O 3.53Å; A193-M199 WeakPolarHBondContact CA-O 3.23Å; A193-M261 HydrophobicContact CB-CE 3.65Å
194S82.7Confident84.6Confident24 Ų2445.3 Ų45.317%0.16825%0.251CS..EExtended strand (participates in β ladder)trans-104.498160-177.80000108.6D197 G198 M199S194-D197 PolarHBondContact O-N 3.25Å; S194-D197 WeakPolarHBondContact OG-CB 3.4Å; S194-D197 PolarHBondContact OG-OD2 3.19Å; S194-G198 PolarHBondContact O-N 2.81Å; S194-M199 PolarHBondContact N-O 2.85Å; S194-M199 PolarHBondContact O-N 3.43Å
195L77.8Confident84.7Confident73 Ų7339.4 Ų39.438%0.38222%0.22SC..THydrogen-bonded Turntrans-66.2-42.5-174.9-50.5-170.8000111.3K82 A193 D197 G198 H260 M261K82-L195 VanDerWaalsContact CE-O 3.26Å; K82-L195 WeakPolarHBondContact CE-O 3.4Å; K82-L195 PolarHBondContact NZ-O 3.14Å; A193-L195 HydrophobicContact CB-CD2 3.73Å; L195-D197 PolarHBondContact O-N 2.77Å; L195-G198 PolarHBondContact O-N 2.71Å; L195-H260 HydrophobicContact CD1-CB 4.33Å; L195-H260 HydrophobicContact CD2-CB 3.43Å; L195-H260 VanDerWaalsContact CD2-CB 3.43Å; L195-M261 HydrophobicContact CD2-CE 3.57Å
196S72.8Confident85Confident82 Ų8235.1 Ų35.157%0.57319%0.189SC*.THydrogen-bonded Turntrans-60.8-30177.656.60000112.6K82K82-S196 WeakPolarHBondContact CE-O 3.2Å; K82-S196 PolarHBondContact NZ-O 3.26Å
197D82.4Confident85.4Confident83 Ų8329.2 Ų29.244%0.44417%0.166SC..THydrogen-bonded Turntrans-100.3-9.2-177.9-50.6-32.9000112.4K165 S194 L195 M199K165-D197 PolarHBondContact NZ-O 3.02Å; S194-D197 PolarHBondContact O-N 3.25Å; S194-D197 WeakPolarHBondContact OG-CB 3.4Å; S194-D197 PolarHBondContact OG-OD2 3.19Å; L195-D197 PolarHBondContact O-N 2.77Å; D197-M199 HydrophobicContact CB-CE 3.54Å; D197-M199 HydrophobicContact CB-CG 4.18Å; D197-M199 HydrophobicContact CB-SD 4.47Å
198G89.1Confident85.7Confident0 Ų025 Ų250%014%0.144CC..THydrogen-bonded Turntrans67.446.5-179.700000111.1K82 C171 I172 S194 L195 M261K82-G198 VanDerWaalsContact NZ-N 3.15Å; C171-G198 CarbonylContact C-O 3.56Å; C171-G198 WeakPolarHBondContact CA-O 3.46Å; C171-G198 VanDerWaalsContact CB-O 3.29Å; C171-G198 WeakPolarHBondContact CB-O 3.31Å; I172-G198 PolarHBondContact N-O 2.63Å; S194-G198 PolarHBondContact O-N 2.81Å; L195-G198 PolarHBondContact O-N 2.71Å; G198-M261 VanDerWaalsContact C-SD 3.51Å; G198-M261 VanDerWaalsContact CA-SD 3.6Å
199M93.3Very high85.6Confident17 Ų1727.4 Ų27.48%0.08416%0.159CC..EExtended strand (participates in β ladder)trans-131.2142.6-179.1-55.8-171.2-70.500110.3L158 L161 G162 I172 A193 S194 D197L158-M199 HydrophobicContact CD2-CB 4.11Å; L161-M199 HydrophobicContact CB-SD 4.3Å; G162-M199 WeakPolarHBondContact CA-SD 3.36Å; G162-M199 PolarHBondContact N-SD 3.42Å; I172-M199 HydrophobicContact CG2-CB 4.33Å; I172-M199 HydrophobicContact CG2-CG 3.83Å; I172-M199 CarbonylContact O-C 3.57Å; I172-M199 VanDerWaalsContact O-CA 3.28Å; I172-M199 WeakPolarHBondContact O-CA 3.49Å; A193-M199 CarbonylContact C-O 3.53Å; A193-M199 WeakPolarHBondContact CA-O 3.23Å; S194-M199 PolarHBondContact N-O 2.85Å; S194-M199 PolarHBondContact O-N 3.43Å; D197-M199 HydrophobicContact CB-CE 3.54Å; D197-M199 HydrophobicContact CB-CG 4.18Å; D197-M199 HydrophobicContact CB-SD 4.47Å
200G92Very high85.9Confident0 Ų032 Ų320%018%0.178CC..EExtended strand (participates in β ladder)trans-145157.7169.600000111.9L161 I172 V173 G174 Q192L161-G200 WeakPolarHBondContact CD1-O 3.4Å; I172-G200 PolarHBondContact O-N 3.03Å; V173-G200 CarbonylContact C-O 3.48Å; V173-G200 WeakPolarHBondContact CA-O 3.47Å; G174-G200 PolarHBondContact N-O 2.99Å; Q192-G200 CarbonylContact O-C 3.6Å; Q192-G200 WeakPolarHBondContact O-CA 3.44Å
201V92.8Very high86.1Confident0 Ų030.9 Ų30.90%017%0.173CC..EExtended strand (participates in β ladder)trans-139.8129.1170.564.30000110.2T154 L157 L158 L161 G174 L180 G191 Q192T154-V201 HydrophobicContact CG2-CG1 4.07Å; L157-V201 HydrophobicContact CB-CB 4.44Å; L157-V201 HydrophobicContact CB-CG1 4.26Å; L157-V201 HydrophobicContact CB-CG2 4.11Å; L157-V201 HydrophobicContact CD1-CG2 3.65Å; L158-V201 HydrophobicContact CD2-CG1 4.12Å; L158-V201 HydrophobicContact CG-CG1 4.12Å; L161-V201 HydrophobicContact CD1-CB 4.27Å; G174-V201 CarbonylContact O-C 3.59Å; G174-V201 VanDerWaalsContact O-CA 3.28Å; G174-V201 WeakPolarHBondContact O-CA 3.19Å; L180-V201 HydrophobicContact CD1-CG2 4.4Å; G191-V201 CarbonylContact C-O 3.51Å; G191-V201 WeakPolarHBondContact CA-O 3.44Å; Q192-V201 PolarHBondContact N-O 2.74Å; Q192-V201 PolarHBondContact O-N 3.36Å
202F92.1Very high86.2Confident0 Ų036.4 Ų36.40%019%0.191CC..EExtended strand (participates in β ladder)trans-137.5154.5-174.1-22.6-66.9000111.1V173 G174 I175 T176 F190 T253 E257V173-F202 HydrophobicContact CB-CE2 3.64Å; V173-F202 HydrophobicContact CB-CZ 4.19Å; V173-F202 HydrophobicContact CG1-CE2 3.65Å; V173-F202 HydrophobicContact CG1-CZ 3.8Å; G174-F202 PolarHBondContact O-N 3.26Å; I175-F202 WeakPolarHBondContact CA-O 3.32Å; T176-F202 PolarHBondContact N-O 2.83Å; F190-F202 CarbonylContact O-C 3.44Å; F190-F202 WeakPolarHBondContact O-CA 3.47Å; F202-T253 HydrophobicContact CB-CG2 3.89Å; F202-T253 HydrophobicContact CG-CG2 4.37Å; F202-E257 HydrophobicContact CD1-CB 3.64Å; F202-E257 HydrophobicContact CD1-CG 3.33Å; F202-E257 HydrophobicContact CD2-CB 4.05Å; F202-E257 HydrophobicContact CD2-CG 4.18Å; F202-E257 HydrophobicContact CE1-CB 3.17Å; F202-E257 HydrophobicContact CE1-CG 3.42Å; F202-E257 VanDerWaalsContact CE1-CG 3.42Å; F202-E257 WeakPolarHBondContact CE1-OE2 3.46Å; F202-E257 HydrophobicContact CE2-CB 3.55Å; F202-E257 HydrophobicContact CE2-CG 4.18Å; F202-E257 HydrophobicContact CG-CB 4.09Å; F202-E257 HydrophobicContact CG-CG 3.77Å; F202-E257 HydrophobicContact CZ-CB 3.11Å; F202-E257 HydrophobicContact CZ-CG 3.86Å
203S91.9Very high86.3Confident2 Ų235.7 Ų35.71%0.01419%0.193CC..EExtended strand (participates in β ladder)trans-126.1136.9-176.8173.20000112.5T176 I178 F190 A205T176-S203 VanDerWaalsContact O-CA 3.26Å; T176-S203 WeakPolarHBondContact O-CA 3.4Å; I178-S203 VanDerWaalsContact C-OG 3.29Å; I178-S203 WeakPolarHBondContact O-CB 3.49Å; I178-S203 PolarHBondContact O-OG 3.24Å; F190-S203 PolarHBondContact O-N 2.75Å; S203-A205 VanDerWaalsContact OG-CB 3.32Å; S203-A205 WeakPolarHBondContact OG-CB 3.45Å; S203-A205 PolarHBondContact OG-N 2.8Å; S203-A205 VanDerWaalsContact OG-N 3.12Å
204F91.1Very high86.4Confident0 Ų044.4 Ų44.40%022%0.219CC..  trans-96.21.5174.6-47.5-48.7000112.6F99 Y109 L113 I175 T176 M177 R206 Y207 L246 S250 T253F99-F204 AromaticContact CE1-CD2 3.7Å; F99-F204 HydrophobicContact CE1-CD2 3.7Å; F99-F204 AromaticContact CE1-CE2 3.83Å; F99-F204 HydrophobicContact CE1-CE2 3.83Å; F99-F204 HydrophobicContact CZ-CD2 4.36Å; F99-F204 HydrophobicContact CZ-CE2 4.37Å; Y109-F204 HydrophobicContact CE1-CD2 4.33Å; Y109-F204 HydrophobicContact CE1-CE2 4.43Å; Y109-F204 WeakPolarHBondContact OH-CD2 3.41Å; L113-F204 HydrophobicContact CD1-CE2 3.66Å; L113-F204 HydrophobicContact CD1-CZ 3.97Å; I175-F204 HydrophobicContact CB-CE2 3.96Å; I175-F204 HydrophobicContact CB-CZ 4.23Å; I175-F204 HydrophobicContact CD1-CE2 4.32Å; I175-F204 HydrophobicContact CG2-CE2 4.18Å; I175-F204 HydrophobicContact CG2-CZ 3.93Å; T176-F204 PolarHBondContact O-N 2.77Å; M177-F204 HydrophobicContact CE-CB 4.04Å; M177-F204 HydrophobicContact CE-CD2 3.99Å; M177-F204 HydrophobicContact SD-CB 3.71Å; M177-F204 HydrophobicContact SD-CD2 4.38Å; F204-R206 PolarHBondContact O-N 3.02Å; F204-Y207 HydrophobicContact CB-CD2 4.05Å; F204-Y207 AromaticContact CD1-CD2 3.95Å; F204-Y207 HydrophobicContact CD1-CD2 3.95Å; F204-Y207 AromaticContact CD1-CE2 3.96Å; F204-Y207 HydrophobicContact CD1-CE2 3.96Å; F204-Y207 HydrophobicContact CG-CD2 4.48Å; F204-Y207 WeakPolarHBondContact O-CB 3.42Å; F204-Y207 PolarHBondContact O-N 3.29Å; F204-L246 HydrophobicContact CB-CD1 4.24Å; F204-S250 WeakPolarHBondContact CD1-OG 3.35Å; F204-S250 WeakPolarHBondContact CG-OG 3.26Å; F204-T253 HydrophobicContact CE1-CG2 4.33Å
205A87.8Confident86.5Confident4 Ų450.4 Ų50.43%0.03325%0.249CC..G310 helixtrans-54.3-42-176.400000112.5M177 D179 S203 Y207 F211M177-A205 VanDerWaalsContact O-CB 3.24Å; M177-A205 WeakPolarHBondContact O-CB 3.23Å; D179-A205 HydrophobicContact CB-CB 4.15Å; S203-A205 VanDerWaalsContact OG-CB 3.32Å; S203-A205 WeakPolarHBondContact OG-CB 3.45Å; S203-A205 PolarHBondContact OG-N 2.8Å; S203-A205 VanDerWaalsContact OG-N 3.12Å; A205-Y207 PolarHBondContact O-N 2.86Å; A205-F211 HydrophobicContact CB-CE2 4.24Å; A205-F211 WeakPolarHBondContact O-CD2 3.48Å
206R88.3Confident86.9Confident8 Ų847.6 Ų47.63%0.0323%0.233CC..G310 helixtrans-79.2-1.3-176.7-69.6-174.7175.3-101.6-5.6114.2D179 F188 F190 F204 D208 F211 Y212D179-R206 IonicContact OD1-CZ 3.66Å; D179-R206 IonicContact OD1-NE 3.91Å; D179-R206 PolarHBondContact OD1-NE 3.31Å; D179-R206 IonicContact OD1-NH2 2.78Å; D179-R206 PolarHBondContact OD1-NH2 3.23Å; D179-R206 IonicContact OD2-CZ 2.82Å; D179-R206 IonicContact OD2-NE 3.74Å; D179-R206 PolarHBondContact OD2-NE 3.33Å; D179-R206 IonicContact OD2-NH2 3.69Å; D179-R206 PolarHBondContact OD2-NH2 2.9Å; F188-R206 VanDerWaalsContact CD2-CZ 3.45Å; F188-R206 VanDerWaalsContact CE2-CD 3.48Å; F190-R206 HydrophobicContact CD1-CB 4.11Å; F190-R206 HydrophobicContact CE1-CB 3.56Å; F190-R206 HydrophobicContact CZ-CB 4.42Å; F204-R206 PolarHBondContact O-N 3.02Å; R206-D208 VanDerWaalsContact C-N 3.34Å; R206-F211 HydrophobicContact CG-CD1 4.13Å; R206-F211 HydrophobicContact CG-CD2 4.22Å; R206-F211 HydrophobicContact CG-CE1 3.71Å; R206-F211 HydrophobicContact CG-CE2 3.75Å; R206-F211 HydrophobicContact CG-CG 4.38Å; R206-F211 HydrophobicContact CG-CZ 3.48Å; R206-F211 VanDerWaalsContact CG-CZ 3.48Å; R206-Y212 PolarHBondContact NH1-OH 3.18Å
207Y87.7Confident87.6Confident8 Ų846.3 Ų46.33%0.03123%0.228CC..G310 helixtrans-92.13.5176.9-63-34.2000113.6F190 F204 A205 R249 T253 L280F190-Y207 HydrophobicContact CD1-CD1 4.43Å; F190-Y207 AromaticContact CD1-CE1 3.58Å; F190-Y207 HydrophobicContact CD1-CE1 3.58Å; F190-Y207 AromaticContact CD1-CZ 3.62Å; F190-Y207 WeakPolarHBondContact CD1-OH 3.33Å; F190-Y207 HydrophobicContact CE1-CD1 4.03Å; F190-Y207 AromaticContact CE1-CE1 3.4Å; F190-Y207 HydrophobicContact CE1-CE1 3.4Å; F190-Y207 AromaticContact CE1-CZ 3.96Å; F190-Y207 HydrophobicContact CZ-CE1 4.3Å; F204-Y207 HydrophobicContact CB-CD2 4.05Å; F204-Y207 AromaticContact CD1-CD2 3.95Å; F204-Y207 HydrophobicContact CD1-CD2 3.95Å; F204-Y207 AromaticContact CD1-CE2 3.96Å; F204-Y207 HydrophobicContact CD1-CE2 3.96Å; F204-Y207 HydrophobicContact CG-CD2 4.48Å; F204-Y207 WeakPolarHBondContact O-CB 3.42Å; F204-Y207 PolarHBondContact O-N 3.29Å; A205-Y207 PolarHBondContact O-N 2.86Å; Y207-R249 HydrophobicContact CD1-CB 3.98Å; Y207-R249 HydrophobicContact CD1-CG 4.26Å; Y207-R249 HydrophobicContact CD2-CB 3.73Å; Y207-R249 HydrophobicContact CE1-CB 4.4Å; Y207-R249 HydrophobicContact CE2-CB 4.21Å; Y207-R249 HydrophobicContact CG-CB 3.63Å; Y207-R249 HydrophobicContact CG-CG 4.28Å; Y207-R249 PolarHBondContact O-NH1 3.49Å; Y207-T253 HydrophobicContact CE2-CG2 4.44Å; Y207-T253 WeakPolarHBondContact CE2-OG1 3.47Å; Y207-T253 VanDerWaalsContact CZ-OG1 3.25Å; Y207-T253 PolarHBondContact OH-OG1 2.98Å; Y207-L280 HydrophobicContact CD1-CD1 3.42Å; Y207-L280 VanDerWaalsContact CD1-CD1 3.42Å; Y207-L280 HydrophobicContact CE1-CD1 3.64Å
208D85.4Confident87.7Confident10 Ų1043.3 Ų43.35%0.05322%0.216CC..SBendtrans-70.4127.4164.1-165.2-53.1000110.6R206 H210 F211 Y216 Y238 P240R206-D208 VanDerWaalsContact C-N 3.34Å; D208-H210 PolarHBondContact O-N 3.17Å; D208-H210 VanDerWaalsContact O-N 3.11Å; D208-H210 WeakPolarHBondContact OD1-CA 3.28Å; D208-H210 WeakPolarHBondContact OD1-CB 3.17Å; D208-H210 IonicContact OD1-CD2 3.96Å; D208-H210 IonicContact OD1-CG 3.93Å; D208-H210 PolarHBondContact OD1-N 3.38Å; D208-F211 HydrophobicContact CB-CB 4.25Å; D208-F211 VanDerWaalsContact O-CB 3.28Å; D208-F211 WeakPolarHBondContact O-CB 3.36Å; D208-F211 PolarHBondContact O-N 3.31Å; D208-Y216 HydrophobicContact CB-CE2 3.94Å; D208-Y216 WeakPolarHBondContact OD2-CE2 3.41Å; D208-Y238 WeakPolarHBondContact OD2-CE1 3.49Å; D208-Y238 PolarHBondContact OD2-OH 3.39Å; D208-P240 HydrophobicContact CB-CB 3.85Å; D208-P240 WeakPolarHBondContact OD2-CB 3.22Å
209D81.9Confident87.7Confident100 Ų10046.7 Ų46.754%0.53523%0.229SC..THydrogen-bonded Turntrans-60.8-21.7178.5-67.3-31.5000113R249D209-R249 IonicContact OD1-CZ 2.64Å; D209-R249 IonicContact OD1-NH1 3.39Å; D209-R249 PolarHBondContact OD1-NH1 2.92Å; D209-R249 IonicContact OD1-NH2 2.71Å; D209-R249 PolarHBondContact OD1-NH2 2.83Å
210H85.3Confident87.4Confident124 Ų12447.5 Ų47.557%0.57424%0.235SC*.THydrogen-bonded Turntrans-98.63.4177.6-58.8-50.7000113.5D208 Y212 S213 Y216D208-H210 PolarHBondContact O-N 3.17Å; D208-H210 VanDerWaalsContact O-N 3.11Å; D208-H210 WeakPolarHBondContact OD1-CA 3.28Å; D208-H210 WeakPolarHBondContact OD1-CB 3.17Å; D208-H210 IonicContact OD1-CD2 3.96Å; D208-H210 IonicContact OD1-CG 3.93Å; D208-H210 PolarHBondContact OD1-N 3.38Å; H210-Y212 VanDerWaalsContact C-N 3.25Å; H210-Y212 PolarHBondContact O-N 3.24Å; H210-Y212 VanDerWaalsContact O-N 3.12Å; H210-S213 WeakPolarHBondContact O-CB 3.36Å; H210-S213 PolarHBondContact O-N 3.32Å; H210-Y216 VanDerWaalsContact C-CD2 3.49Å; H210-Y216 HydrophobicContact CB-CD2 4.1Å; H210-Y216 WeakPolarHBondContact O-CB 3.35Å; H210-Y216 WeakPolarHBondContact O-CD2 3.38Å
211F85.6Confident86.6Confident5 Ų556.9 Ų56.92%0.02228%0.276CS..THydrogen-bonded Turntrans-52.1-41.2-173.8-174.1-91000113.7N149 D179 A205 R206 D208 S213 Y216N149-F211 WeakPolarHBondContact ND2-CE2 3.49Å; N149-F211 WeakPolarHBondContact ND2-CZ 3.48Å; D179-F211 HydrophobicContact CB-CZ 4.45Å; A205-F211 HydrophobicContact CB-CE2 4.24Å; A205-F211 WeakPolarHBondContact O-CD2 3.48Å; R206-F211 HydrophobicContact CG-CD1 4.13Å; R206-F211 HydrophobicContact CG-CD2 4.22Å; R206-F211 HydrophobicContact CG-CE1 3.71Å; R206-F211 HydrophobicContact CG-CE2 3.75Å; R206-F211 HydrophobicContact CG-CG 4.38Å; R206-F211 HydrophobicContact CG-CZ 3.48Å; R206-F211 VanDerWaalsContact CG-CZ 3.48Å; D208-F211 HydrophobicContact CB-CB 4.25Å; D208-F211 VanDerWaalsContact O-CB 3.28Å; D208-F211 WeakPolarHBondContact O-CB 3.36Å; D208-F211 PolarHBondContact O-N 3.31Å; F211-S213 VanDerWaalsContact C-N 3.35Å; F211-Y216 AromaticContact CD2-CE1 3.78Å; F211-Y216 HydrophobicContact CD2-CE1 3.78Å; F211-Y216 AromaticContact CD2-CZ 3.84Å; F211-Y216 HydrophobicContact CE2-CE1 4.23Å
212Y83.6Confident85.6Confident130 Ų13065.2 Ų65.251%0.5131%0.312SS..THydrogen-bonded Turntrans-88.60.7-179.4-60.4-74.4000113.8R206 H210R206-Y212 PolarHBondContact NH1-OH 3.18Å; H210-Y212 VanDerWaalsContact C-N 3.25Å; H210-Y212 PolarHBondContact O-N 3.24Å; H210-Y212 VanDerWaalsContact O-N 3.12Å
213S86Confident84.4Confident48 Ų4875.6 Ų75.634%0.33636%0.357SS..SBendtrans-69.4142.8177.7178.70000111.5H210 F211 N215 Y216H210-S213 WeakPolarHBondContact O-CB 3.36Å; H210-S213 PolarHBondContact O-N 3.32Å; F211-S213 VanDerWaalsContact C-N 3.35Å; S213-N215 PolarHBondContact O-N 3.15Å; S213-N215 VanDerWaalsContact O-N 3.15Å; S213-N215 PolarHBondContact OG-N 2.89Å; S213-Y216 VanDerWaalsContact O-CB 3.27Å; S213-Y216 WeakPolarHBondContact O-CB 3.38Å; S213-Y216 PolarHBondContact O-N 3.27Å
214R84.2Confident83.6Confident215 Ų21579 Ų7981%0.81138%0.375SS*.THydrogen-bonded Turntrans-58.7-28.3172.6-70-176178.3-177.60.4112.5R219R214-R219 PolarHBondContact O-NH1 2.95Å
215N84.9Confident82.8Confident149 Ų14987.2 Ų87.280%0.79741%0.413SS*.THydrogen-bonded Turntrans-99.415.2-178.9-61.7-22.2000112.6S213 A217S213-N215 PolarHBondContact O-N 3.15Å; S213-N215 VanDerWaalsContact O-N 3.15Å; S213-N215 PolarHBondContact OG-N 2.89Å; N215-A217 PolarHBondContact O-N 2.92Å
216Y87.6Confident82.6Confident14 Ų1489.3 Ų89.36%0.05542%0.424CS..  trans-56.7128.5178.5-178.3-118.9000111.3N149 D208 H210 F211 S213 G218 R219 Y238N149-Y216 WeakPolarHBondContact ND2-CE1 3.47Å; D208-Y216 HydrophobicContact CB-CE2 3.94Å; D208-Y216 WeakPolarHBondContact OD2-CE2 3.41Å; H210-Y216 VanDerWaalsContact C-CD2 3.49Å; H210-Y216 HydrophobicContact CB-CD2 4.1Å; H210-Y216 WeakPolarHBondContact O-CB 3.35Å; H210-Y216 WeakPolarHBondContact O-CD2 3.38Å; F211-Y216 AromaticContact CD2-CE1 3.78Å; F211-Y216 HydrophobicContact CD2-CE1 3.78Å; F211-Y216 AromaticContact CD2-CZ 3.84Å; F211-Y216 HydrophobicContact CE2-CE1 4.23Å; S213-Y216 VanDerWaalsContact O-CB 3.27Å; S213-Y216 WeakPolarHBondContact O-CB 3.38Å; S213-Y216 PolarHBondContact O-N 3.27Å; Y216-G218 PolarHBondContact O-N 2.9Å; Y216-R219 HydrophobicContact CD1-CG 4.13Å; Y216-R219 WeakPolarHBondContact O-CB 3.5Å; Y216-R219 WeakPolarHBondContact O-CG 3.28Å; Y216-R219 PolarHBondContact O-N 3.49Å; Y216-R219 VanDerWaalsContact O-N 3.15Å; Y216-Y238 HydrophobicContact CD2-CE1 4.37Å; Y216-Y238 HydrophobicContact CE1-CD1 4.28Å; Y216-Y238 AromaticContact CE2-CD1 3.94Å; Y216-Y238 HydrophobicContact CE2-CD1 3.94Å; Y216-Y238 AromaticContact CE2-CE1 3.44Å; Y216-Y238 HydrophobicContact CE2-CE1 3.44Å; Y216-Y238 VanDerWaalsContact CE2-CE1 3.44Å; Y216-Y238 AromaticContact CZ-CD1 3.63Å; Y216-Y238 AromaticContact CZ-CE1 3.58Å; Y216-Y238 WeakPolarHBondContact OH-CD1 3.46Å; Y216-Y238 WeakPolarHBondContact OH-CE1 3.36Å
217A86Confident82.5Confident55 Ų5597.5 Ų97.546%0.45546%0.455SS..THydrogen-bonded Turntrans-66.1-26.5-171.900000113N215 R219 Y238N215-A217 PolarHBondContact O-N 2.92Å; A217-R219 VanDerWaalsContact C-N 3.29Å; A217-R219 PolarHBondContact O-N 3.25Å; A217-Y238 HydrophobicContact CB-CD1 4.16Å; A217-Y238 HydrophobicContact CB-CD2 3.42Å; A217-Y238 VanDerWaalsContact CB-CD2 3.42Å; A217-Y238 HydrophobicContact CB-CE1 4.22Å; A217-Y238 HydrophobicContact CB-CE2 3.5Å; A217-Y238 VanDerWaalsContact CB-CE2 3.5Å; A217-Y238 HydrophobicContact CB-CG 3.75Å
218G85.9Confident82.6Confident20 Ų20102.8 Ų102.821%0.20648%0.48CS..THydrogen-bonded Turntrans-77.3-4.2176.400000115.8N149 Y216 Y238N149-G218 PolarHBondContact OD1-O 2.76Å; Y216-G218 PolarHBondContact O-N 2.9Å; G218-Y238 VanDerWaalsContact CA-CB 3.49Å
219R88.6Confident82.7Confident71 Ų71104.9 Ų104.927%0.26850%0.504SS..SBendtrans-71.1132.1177.2-63.4-179.282.3-1534.4110.7S147 H148 N149 R214 Y216 A217 K221S147-R219 WeakPolarHBondContact O-CG 3.25Å; S147-R219 PolarHBondContact O-NE 3.25Å; S147-R219 VanDerWaalsContact O-NE 3.08Å; H148-R219 PolarHBondContact CD2-NH2 3.41Å; N149-R219 WeakPolarHBondContact OD1-CA 3.46Å; N149-R219 WeakPolarHBondContact OD1-CG 3.38Å; N149-R219 PolarHBondContact OD1-N 2.91Å; R214-R219 PolarHBondContact O-NH1 2.95Å; Y216-R219 HydrophobicContact CD1-CG 4.13Å; Y216-R219 WeakPolarHBondContact O-CB 3.5Å; Y216-R219 WeakPolarHBondContact O-CG 3.28Å; Y216-R219 PolarHBondContact O-N 3.49Å; Y216-R219 VanDerWaalsContact O-N 3.15Å; A217-R219 VanDerWaalsContact C-N 3.29Å; A217-R219 PolarHBondContact O-N 3.25Å; R219-K221 PolarHBondContact O-N 2.94Å; R219-K221 VanDerWaalsContact O-N 3.14Å
220V86.6Confident83.2Confident34 Ų34103.3 Ų103.321%0.20650%0.495CS..  trans-71.6109.3176-174.10000109.1V143 H148 L150 K222 L224V143-V220 HydrophobicContact CG2-CG2 4.45Å; H148-V220 WeakPolarHBondContact O-CG2 3.29Å; H148-V220 PolarHBondContact O-N 2.92Å; L150-V220 HydrophobicContact CD2-CG2 4.5Å; L150-V220 HydrophobicContact CG-CG2 4.07Å; V220-K222 PolarHBondContact O-N 3.33Å; V220-L224 HydrophobicContact CG1-CB 3.88Å; V220-L224 HydrophobicContact CG1-CD1 4.12Å; V220-L224 HydrophobicContact CG1-CD2 4.27Å; V220-L224 HydrophobicContact CG1-CG 4.33Å
221K75.2Confident83.5Confident198 Ų19899.3 Ų99.386%0.86148%0.476SS*.  trans-72.4-21-169.6-64.2-178.4-179175.10115.3R219R219-K221 PolarHBondContact O-N 2.94Å; R219-K221 VanDerWaalsContact O-N 3.14Å
222K71.3Confident83.8Confident174 Ų174101.8 Ų101.876%0.75749%0.493SS*.SBendtrans-119.5157.8-179.1-68-177.8180177.50109.7V220 L224V220-K222 PolarHBondContact O-N 3.33Å; K222-L224 PolarHBondContact O-N 2.92Å
223K68.2Low84.1Confident218 Ų21897 Ų9795%0.94848%0.478SS*.  trans-62.787165.6-77.9-174.2177.3-179.10108.5Q225K223-Q225 PolarHBondContact O-N 3.45Å
224L73.4Confident84.3Confident75 Ų7595.5 Ų95.539%0.39347%0.465SS..  trans-71.1118.4174.4-136.678.8000107V220 K222 L226 V233V220-L224 HydrophobicContact CG1-CB 3.88Å; V220-L224 HydrophobicContact CG1-CD1 4.12Å; V220-L224 HydrophobicContact CG1-CD2 4.27Å; V220-L224 HydrophobicContact CG1-CG 4.33Å; K222-L224 PolarHBondContact O-N 2.92Å; L224-L226 HydrophobicContact CB-CD2 4.45Å; L224-L226 HydrophobicContact CD2-CD2 3.77Å; L224-L226 PolarHBondContact O-N 3.04Å; L224-V233 HydrophobicContact CD2-CB 4.01Å; L224-V233 HydrophobicContact CD2-CG1 3.65Å
225Q75.1Confident84.4Confident171 Ų17193 Ų9380%0.79946%0.462SS*.  trans-78.399.3165.8-72.2-157.1-7.100107.7K223K223-Q225 PolarHBondContact O-N 3.45Å
226L83.6Confident84.2Confident49 Ų4989.9 Ų89.926%0.25747%0.466SS..  trans-68.6134.3175.1-62-179.5000109.9F141 R142 V143 L150 L224 V233F141-L226 HydrophobicContact CD2-CD1 4.08Å; F141-L226 HydrophobicContact CD2-CD2 4.22Å; F141-L226 HydrophobicContact CE2-CB 4.25Å; F141-L226 HydrophobicContact CE2-CD1 4.41Å; F141-L226 HydrophobicContact CE2-CD2 3.97Å; F141-L226 HydrophobicContact CE2-CG 4.45Å; R142-L226 VanDerWaalsContact C-CD1 3.49Å; V143-L226 HydrophobicContact CB-CD1 4.45Å; V143-L226 HydrophobicContact CG2-CD1 3.69Å; V143-L226 HydrophobicContact CG2-CD2 4.26Å; V143-L226 HydrophobicContact CG2-CG 4.07Å; L150-L226 HydrophobicContact CD2-CD2 4.17Å; L224-L226 HydrophobicContact CB-CD2 4.45Å; L224-L226 HydrophobicContact CD2-CD2 3.77Å; L224-L226 PolarHBondContact O-N 3.04Å; L226-V233 HydrophobicContact CD2-CG1 4.07Å; L226-V233 HydrophobicContact CD2-CG2 4.5Å
227R87.3Confident84.1Confident179 Ų17991 Ų9168%0.67547%0.47SS*.  trans-114.9123.2166.6-65.1-180-178.9-1780.5107.1F141 G229 D230F141-R227 WeakPolarHBondContact CZ-O 3.45Å; R227-G229 PolarHBondContact O-N 3.5Å; R227-D230 HydrophobicContact CB-CB 4.12Å; R227-D230 WeakPolarHBondContact O-CB 3.3Å; R227-D230 PolarHBondContact O-N 3.07Å
228Q88.4Confident84.1Confident119 Ų11992.1 Ų92.156%0.55646%0.463SS*.THydrogen-bonded Turntrans-57.8136.4175.1-68.8-57.6-28.400109.5F141 D230F141-Q228 PolarHBondContact O-NE2 3.39Å; Q228-D230 VanDerWaalsContact C-N 3.33Å
229G88.1Confident84.1Confident54 Ų5492.3 Ų92.356%0.55746%0.46SS*.THydrogen-bonded Turntrans86.9-12.7-173.200000115.4R227 Y231R227-G229 PolarHBondContact O-N 3.5Å; G229-Y231 VanDerWaalsContact O-CD2 3.29Å; G229-Y231 WeakPolarHBondContact O-CD2 3.42Å; G229-Y231 PolarHBondContact O-N 2.73Å
230D92.4Very high83.9Confident68 Ų6889.1 Ų89.136%0.36445%0.449SS..  trans-88.984.9172.4-175.34.2000111.1F141 R227 Q228 S232F141-D230 WeakPolarHBondContact CZ-O 3.48Å; R227-D230 HydrophobicContact CB-CB 4.12Å; R227-D230 WeakPolarHBondContact O-CB 3.3Å; R227-D230 PolarHBondContact O-N 3.07Å; Q228-D230 VanDerWaalsContact C-N 3.33Å; D230-S232 PolarHBondContact O-N 2.91Å; D230-S232 VanDerWaalsContact OD1-CB 3.29Å; D230-S232 WeakPolarHBondContact OD1-CB 3.37Å; D230-S232 PolarHBondContact OD1-N 3.25Å; D230-S232 PolarHBondContact OD1-OG 3.22Å
231Y92.6Very high83.8Confident40 Ų4091.3 Ų91.316%0.15746%0.464CS..G310 helixtrans-79.21.5-179.3-64.7-83.4000114V134 S135 G138 C139 F141 G229 V233 F234V134-Y231 HydrophobicContact CB-CD1 4.28Å; V134-Y231 HydrophobicContact CG1-CD1 3.86Å; V134-Y231 HydrophobicContact CG1-CE1 4.07Å; S135-Y231 VanDerWaalsContact CA-CG 3.48Å; G138-Y231 VanDerWaalsContact CA-OH 3.27Å; G138-Y231 WeakPolarHBondContact CA-OH 3.39Å; G138-Y231 PolarHBondContact O-OH 2.81Å; C139-Y231 PolarHBondContact N-OH 3.14Å; C139-Y231 WeakPolarHBondContact O-CE1 3.36Å; C139-Y231 PolarHBondContact O-OH 2.64Å; F141-Y231 HydrophobicContact CD1-CD1 4.15Å; F141-Y231 AromaticContact CD1-CE1 3.72Å; F141-Y231 HydrophobicContact CD1-CE1 3.72Å; F141-Y231 AromaticContact CE1-CD1 3.82Å; F141-Y231 HydrophobicContact CE1-CD1 3.82Å; F141-Y231 AromaticContact CE1-CE1 3.6Å; F141-Y231 HydrophobicContact CE1-CE1 3.6Å; F141-Y231 HydrophobicContact CE1-CG 4.4Å; G229-Y231 VanDerWaalsContact O-CD2 3.29Å; G229-Y231 WeakPolarHBondContact O-CD2 3.42Å; G229-Y231 PolarHBondContact O-N 2.73Å; Y231-V233 PolarHBondContact O-N 3.07Å; Y231-V233 VanDerWaalsContact O-N 3.11Å; Y231-F234 AromaticContact CD1-CD2 3.98Å; Y231-F234 HydrophobicContact CD1-CD2 3.98Å; Y231-F234 AromaticContact CD1-CE2 3.99Å; Y231-F234 HydrophobicContact CD1-CE2 3.99Å; Y231-F234 PolarHBondContact O-N 2.87Å
232S91Very high84.4Confident56 Ų5683.8 Ų83.839%0.39243%0.433SS..G310 helixtrans-60.2-22.3175.1690000112.2D230 F234 Q235D230-S232 PolarHBondContact O-N 2.91Å; D230-S232 VanDerWaalsContact OD1-CB 3.29Å; D230-S232 WeakPolarHBondContact OD1-CB 3.37Å; D230-S232 PolarHBondContact OD1-N 3.25Å; D230-S232 PolarHBondContact OD1-OG 3.22Å; S232-F234 PolarHBondContact O-N 3.31Å; S232-F234 VanDerWaalsContact O-N 3.12Å; S232-Q235 WeakPolarHBondContact O-CB 3.4Å; S232-Q235 WeakPolarHBondContact O-CG 3.47Å; S232-Q235 PolarHBondContact O-N 3.25Å
233V89.3Confident85.3Confident30 Ų3078 Ų7818%0.18241%0.412CS..G310 helixtrans-60.6-18.5174.1-55.30000113.8F141 L150 L224 L226 Y231F141-V233 HydrophobicContact CD2-CG2 4.26Å; F141-V233 HydrophobicContact CE2-CG2 3.84Å; F141-V233 HydrophobicContact CZ-CG2 4.24Å; L150-V233 HydrophobicContact CD1-CG2 4.49Å; L150-V233 WeakPolarHBondContact CD1-O 3.35Å; L150-V233 HydrophobicContact CD2-CG2 4.37Å; L224-V233 HydrophobicContact CD2-CB 4.01Å; L224-V233 HydrophobicContact CD2-CG1 3.65Å; L226-V233 HydrophobicContact CD2-CG1 4.07Å; L226-V233 HydrophobicContact CD2-CG2 4.5Å; Y231-V233 PolarHBondContact O-N 3.07Å; Y231-V233 VanDerWaalsContact O-N 3.11Å
234F90.1Very high86.5Confident17 Ų1768.5 Ų68.58%0.07537%0.373CS..G310 helixtrans-96.89175.1-61.6-77.5000113V134 F141 L150 I152 I178 Y231 S232 G236 Y237V134-F234 HydrophobicContact CB-CB 4.41Å; V134-F234 HydrophobicContact CB-CD2 4.02Å; V134-F234 HydrophobicContact CB-CE2 4.46Å; V134-F234 HydrophobicContact CB-CG 4.11Å; V134-F234 HydrophobicContact CG1-CD1 4.46Å; V134-F234 HydrophobicContact CG1-CD2 3.79Å; V134-F234 HydrophobicContact CG1-CE1 4.4Å; V134-F234 HydrophobicContact CG1-CE2 3.72Å; V134-F234 HydrophobicContact CG1-CG 4.17Å; V134-F234 HydrophobicContact CG1-CZ 4.04Å; V134-F234 HydrophobicContact CG2-CB 4.1Å; V134-F234 HydrophobicContact CG2-CD1 4.1Å; V134-F234 HydrophobicContact CG2-CD2 4.35Å; V134-F234 HydrophobicContact CG2-CG 3.93Å; F141-F234 HydrophobicContact CB-CE2 4.06Å; F141-F234 HydrophobicContact CB-CZ 3.69Å; F141-F234 AromaticContact CD1-CE2 3.76Å; F141-F234 HydrophobicContact CD1-CE2 3.76Å; F141-F234 HydrophobicContact CD1-CZ 4.28Å; F141-F234 HydrophobicContact CD2-CE2 4.14Å; F141-F234 HydrophobicContact CD2-CZ 4.31Å; F141-F234 HydrophobicContact CE1-CE2 4.2Å; F141-F234 AromaticContact CG-CE2 3.73Å; F141-F234 HydrophobicContact CG-CE2 3.73Å; F141-F234 AromaticContact CG-CZ 3.86Å; F141-F234 HydrophobicContact CG-CZ 3.86Å; L150-F234 HydrophobicContact CB-CE1 3.93Å; L150-F234 HydrophobicContact CD1-CD1 3.92Å; L150-F234 HydrophobicContact CD1-CE1 3.87Å; L150-F234 HydrophobicContact CG-CE1 4.37Å; I152-F234 HydrophobicContact CG2-CE1 3.88Å; I152-F234 HydrophobicContact CG2-CE2 4.43Å; I152-F234 HydrophobicContact CG2-CZ 3.53Å; I178-F234 HydrophobicContact CD1-CD1 3.8Å; I178-F234 HydrophobicContact CD1-CE1 4Å; I178-F234 HydrophobicContact CG2-CE1 3.99Å; Y231-F234 AromaticContact CD1-CD2 3.98Å; Y231-F234 HydrophobicContact CD1-CD2 3.98Å; Y231-F234 AromaticContact CD1-CE2 3.99Å; Y231-F234 HydrophobicContact CD1-CE2 3.99Å; Y231-F234 PolarHBondContact O-N 2.87Å; S232-F234 PolarHBondContact O-N 3.31Å; S232-F234 VanDerWaalsContact O-N 3.12Å; F234-G236 PolarHBondContact O-N 2.93Å; F234-Y237 HydrophobicContact CB-CD1 3.93Å; F234-Y237 HydrophobicContact CB-CE1 4.36Å; F234-Y237 HydrophobicContact CD1-CD1 4.12Å; F234-Y237 WeakPolarHBondContact O-CD1 3.31Å
235Q86.6Confident87.5Confident161 Ų16167.1 Ų67.175%0.75237%0.367SS*.THydrogen-bonded Turntrans-76.3118.2171.3-69-178.4-7.500109.7S232 Y237S232-Q235 WeakPolarHBondContact O-CB 3.4Å; S232-Q235 WeakPolarHBondContact O-CG 3.47Å; S232-Q235 PolarHBondContact O-N 3.25Å; Q235-Y237 VanDerWaalsContact C-N 3.3Å; Q235-Y237 PolarHBondContact O-N 2.86Å
236G81.6Confident88.3Confident84 Ų8459.1 Ų59.187%0.86633%0.33SS*.THydrogen-bonded Turntrans63.831.2179.100000113.9F234F234-G236 PolarHBondContact O-N 2.93Å
237Y85.9Confident88.8Confident39 Ų3956.8 Ų56.815%0.15332%0.318CS..  trans-61.9149.3171.370.2-98.8000109.9G97 S98 M177 I178 F234 Q235 T239G97-Y237 WeakPolarHBondContact CA-OH 3.35Å; S98-Y237 WeakPolarHBondContact CA-OH 3.48Å; S98-Y237 PolarHBondContact N-OH 2.79Å; S98-Y237 PolarHBondContact O-OH 3.38Å; M177-Y237 HydrophobicContact CB-CE2 4.36Å; I178-Y237 HydrophobicContact CD1-CD1 4.33Å; I178-Y237 HydrophobicContact CD1-CE1 3.67Å; I178-Y237 HydrophobicContact CD1-CE2 4.2Å; I178-Y237 HydrophobicContact CG1-CD1 4.43Å; I178-Y237 HydrophobicContact CG1-CD2 4.08Å; I178-Y237 HydrophobicContact CG1-CE1 3.91Å; I178-Y237 HydrophobicContact CG1-CE2 3.5Å; I178-Y237 VanDerWaalsContact CG1-CE2 3.5Å; F234-Y237 HydrophobicContact CB-CD1 3.93Å; F234-Y237 HydrophobicContact CB-CE1 4.36Å; F234-Y237 HydrophobicContact CD1-CD1 4.12Å; F234-Y237 WeakPolarHBondContact O-CD1 3.31Å; Q235-Y237 VanDerWaalsContact C-N 3.3Å; Q235-Y237 PolarHBondContact O-N 2.86Å; Y237-T239 HydrophobicContact CD2-CG2 4.18Å; Y237-T239 HydrophobicContact CE2-CG2 3.68Å; Y237-T239 PolarHBondContact O-N 3.5Å
238Y86.1Confident89.3Confident77 Ų7749.4 Ų49.430%0.30229%0.292SS..  trans-65.8132.1-177.7177.3-104.2000111.8D208 Y216 A217 G218 P241D208-Y238 WeakPolarHBondContact OD2-CE1 3.49Å; D208-Y238 PolarHBondContact OD2-OH 3.39Å; Y216-Y238 HydrophobicContact CD2-CE1 4.37Å; Y216-Y238 HydrophobicContact CE1-CD1 4.28Å; Y216-Y238 AromaticContact CE2-CD1 3.94Å; Y216-Y238 HydrophobicContact CE2-CD1 3.94Å; Y216-Y238 AromaticContact CE2-CE1 3.44Å; Y216-Y238 HydrophobicContact CE2-CE1 3.44Å; Y216-Y238 VanDerWaalsContact CE2-CE1 3.44Å; Y216-Y238 AromaticContact CZ-CD1 3.63Å; Y216-Y238 AromaticContact CZ-CE1 3.58Å; Y216-Y238 WeakPolarHBondContact OH-CD1 3.46Å; Y216-Y238 WeakPolarHBondContact OH-CE1 3.36Å; A217-Y238 HydrophobicContact CB-CD1 4.16Å; A217-Y238 HydrophobicContact CB-CD2 3.42Å; A217-Y238 VanDerWaalsContact CB-CD2 3.42Å; A217-Y238 HydrophobicContact CB-CE1 4.22Å; A217-Y238 HydrophobicContact CB-CE2 3.5Å; A217-Y238 VanDerWaalsContact CB-CE2 3.5Å; A217-Y238 HydrophobicContact CB-CG 3.75Å; G218-Y238 VanDerWaalsContact CA-CB 3.49Å; Y238-P241 WeakPolarHBondContact OH-CD 3.46Å
239T85.8Confident89.6Confident24 Ų2444.3 Ų44.315%0.14727%0.268CS..  trans-114.6136.6168.852.50000109.4S98 G100 M177 Y237S98-T239 WeakPolarHBondContact O-CG2 3.49Å; G100-T239 WeakPolarHBondContact CA-OG1 3.31Å; G100-T239 PolarHBondContact N-OG1 3.37Å; M177-T239 HydrophobicContact CB-CG2 4Å; M177-T239 HydrophobicContact CG-CG2 4.4Å; Y237-T239 HydrophobicContact CD2-CG2 4.18Å; Y237-T239 HydrophobicContact CE2-CG2 3.68Å; Y237-T239 PolarHBondContact O-N 3.5Å
240P83.9Confident89.9Confident5 Ų541.8 Ų41.83%0.03224%0.241CC..  trans-62.9149.2178.928.7-36.4000111.4M177 D208 L246M177-P240 HydrophobicContact CE-CG 4.4Å; M177-P240 HydrophobicContact SD-CG 3.6Å; D208-P240 HydrophobicContact CB-CB 3.85Å; D208-P240 WeakPolarHBondContact OD2-CB 3.22Å; P240-L246 HydrophobicContact CB-CD2 4.17Å; P240-L246 HydrophobicContact CG-CD2 3.88Å
241P84.8Confident90.1Very high79 Ų7938.5 Ų38.551%0.51322%0.224SC..  trans-62.5143.3173.327.5-34.6000110.8Y238 T243 L246Y238-P241 WeakPolarHBondContact OH-CD 3.46Å; P241-T243 HydrophobicContact CG-CG2 4.39Å; P241-T243 PolarHBondContact O-N 3.26Å; P241-T243 VanDerWaalsContact O-N 3.13Å; P241-L246 VanDerWaalsContact O-CD2 3.31Å; P241-L246 WeakPolarHBondContact O-CD2 3.4Å
242I87.4Confident90.2Very high41 Ų4137.2 Ų37.221%0.2122%0.219CC..  trans-74.7104.7176.5-61.9157.9000109Q105 Y109 W112 P342Q105-I242 HydrophobicContact CB-CD1 4.32Å; Y109-I242 HydrophobicContact CD2-CD1 4.49Å; Y109-I242 HydrophobicContact CD2-CG1 4.12Å; Y109-I242 HydrophobicContact CD2-CG2 3.68Å; Y109-I242 HydrophobicContact CE2-CG2 4.34Å; Y109-I242 HydrophobicContact CG-CD1 4.16Å; Y109-I242 HydrophobicContact CG-CG1 4.19Å; Y109-I242 HydrophobicContact CG-CG2 4.41Å; W112-I242 HydrophobicContact CZ3-CG2 4.13Å; I242-P342 HydrophobicContact CG2-CG 4.27Å
243T90.8Very high90.3Very high53 Ų5334.9 Ų34.933%0.32520%0.202SC..  trans-115.2165175.967.80000110.7P241 T245 L246 L247P241-T243 HydrophobicContact CG-CG2 4.39Å; P241-T243 PolarHBondContact O-N 3.26Å; P241-T243 VanDerWaalsContact O-N 3.13Å; T243-T245 VanDerWaalsContact C-N 3.27Å; T243-T245 PolarHBondContact O-N 3.05Å; T243-L246 PolarHBondContact O-N 3.48Å; T243-L246 WeakPolarHBondContact OG1-CB 3.29Å; T243-L246 PolarHBondContact OG1-N 3.45Å; T243-L246 VanDerWaalsContact OG1-N 3.09Å; T243-L247 PolarHBondContact O-N 3.05Å
244S93.4Very high90.5Very high18 Ų1833.4 Ų33.413%0.12619%0.193CC..Hα-helixtrans-63.3-34174.645.40000113L247 L248 P342 E344S244-L247 PolarHBondContact O-N 3.38Å; S244-L248 WeakPolarHBondContact O-CB 3.12Å; S244-L248 PolarHBondContact O-N 2.73Å; S244-P342 WeakPolarHBondContact CA-O 3.09Å; S244-P342 VanDerWaalsContact CB-C 3.48Å; S244-P342 WeakPolarHBondContact CB-O 3.05Å; S244-E344 WeakPolarHBondContact CB-OE2 3.45Å; S244-E344 PolarHBondContact OG-OE2 2.92Å
245T93.7Very high90.8Very high45 Ų4532.7 Ų32.728%0.27619%0.19SC..Hα-helixtrans-64.4-45.1173.3-530000111.7T243 L248 R249T243-T245 VanDerWaalsContact C-N 3.27Å; T243-T245 PolarHBondContact O-N 3.05Å; T245-L248 PolarHBondContact O-N 2.83Å; T245-R249 WeakPolarHBondContact O-CB 3.27Å; T245-R249 WeakPolarHBondContact O-CG 3.33Å; T245-R249 PolarHBondContact O-N 3.39Å
246L92.3Very high91.2Very high3 Ų326.1 Ų26.12%0.01616%0.159CC..Hα-helixtrans-61.5-46176.7-179.561.8000110.5M177 F204 P240 P241 T243 R249 S250M177-L246 HydrophobicContact CE-CD2 4.09Å; F204-L246 HydrophobicContact CB-CD1 4.24Å; P240-L246 HydrophobicContact CB-CD2 4.17Å; P240-L246 HydrophobicContact CG-CD2 3.88Å; P241-L246 VanDerWaalsContact O-CD2 3.31Å; P241-L246 WeakPolarHBondContact O-CD2 3.4Å; T243-L246 PolarHBondContact O-N 3.48Å; T243-L246 WeakPolarHBondContact OG1-CB 3.29Å; T243-L246 PolarHBondContact OG1-N 3.45Å; T243-L246 VanDerWaalsContact OG1-N 3.09Å; L246-R249 PolarHBondContact O-N 3.02Å; L246-S250 VanDerWaalsContact O-CB 3.31Å; L246-S250 WeakPolarHBondContact O-CB 3.16Å; L246-S250 PolarHBondContact O-N 3.16Å; L246-S250 PolarHBondContact O-OG 3.13Å
247L94.3Very high91.6Very high0 Ų023.3 Ų23.30%012%0.124CC..Hα-helixtrans-60.5-46.4177.5-176.258.5000111.4Y109 W112 L113 T243 S244 R249 S250 C251 W316 K341 P342 F346Y109-L247 HydrophobicContact CD2-CD1 4.1Å; Y109-L247 HydrophobicContact CE2-CB 4.41Å; Y109-L247 HydrophobicContact CE2-CD1 3.82Å; W112-L247 HydrophobicContact CB-CD1 4.43Å; W112-L247 HydrophobicContact CE3-CD2 4.25Å; L113-L247 HydrophobicContact CD2-CD1 3.98Å; L113-L247 HydrophobicContact CG-CD1 4.45Å; T243-L247 PolarHBondContact O-N 3.05Å; S244-L247 PolarHBondContact O-N 3.38Å; L247-R249 PolarHBondContact O-N 2.91Å; L247-S250 PolarHBondContact O-N 2.97Å; L247-C251 WeakPolarHBondContact O-CB 3.49Å; L247-C251 PolarHBondContact O-N 2.68Å; L247-C251 PolarHBondContact O-SG 2.83Å; L247-W316 HydrophobicContact CD1-CH2 4.48Å; L247-W316 HydrophobicContact CD2-CH2 4.01Å; L247-W316 HydrophobicContact CD2-CZ2 4.41Å; L247-W316 HydrophobicContact CG-CH2 4.21Å; L247-K341 HydrophobicContact CD2-CG 3.95Å; L247-P342 HydrophobicContact CD2-CG 4.35Å; L247-F346 HydrophobicContact CB-CE2 4.29Å; L247-F346 HydrophobicContact CD2-CE2 4.27Å; L247-F346 HydrophobicContact CD2-CZ 4.49Å; L247-F346 HydrophobicContact CG-CE2 4.07Å; L247-F346 HydrophobicContact CG-CZ 4.02Å
248L96.4Very high92Very high24 Ų2421.4 Ų21.413%0.12612%0.116CC..Hα-helixtrans-58-49.1176.5178.968.1000112.3S244 T245 S250 C251 K252 L288 A345 F346S244-L248 WeakPolarHBondContact O-CB 3.12Å; S244-L248 PolarHBondContact O-N 2.73Å; T245-L248 PolarHBondContact O-N 2.83Å; L248-S250 VanDerWaalsContact C-N 3.26Å; L248-S250 PolarHBondContact O-N 2.8Å; L248-C251 PolarHBondContact O-N 3.29Å; L248-K252 WeakPolarHBondContact O-CG 3.08Å; L248-K252 PolarHBondContact O-N 3.45Å; L248-L288 HydrophobicContact CD1-CB 4.43Å; L248-L288 HydrophobicContact CD1-CD1 4.01Å; L248-L288 HydrophobicContact CD1-CD2 3.89Å; L248-L288 HydrophobicContact CD1-CG 4.34Å; L248-A345 HydrophobicContact CB-CB 4.17Å; L248-A345 HydrophobicContact CD2-CB 3.96Å; L248-F346 VanDerWaalsContact CA-CZ 3.41Å; L248-F346 HydrophobicContact CB-CD2 4.32Å; L248-F346 HydrophobicContact CB-CE1 4.5Å; L248-F346 HydrophobicContact CB-CE2 3.78Å; L248-F346 HydrophobicContact CB-CZ 3.9Å; L248-F346 HydrophobicContact CD1-CD1 3.78Å; L248-F346 HydrophobicContact CD1-CD2 4.35Å; L248-F346 HydrophobicContact CD1-CE1 3.67Å; L248-F346 HydrophobicContact CD1-CE2 4.27Å; L248-F346 HydrophobicContact CD1-CG 4.14Å; L248-F346 HydrophobicContact CD1-CZ 3.95Å
249R95Very high92.4Very high13 Ų1317.9 Ų17.95%0.04910%0.103CC..Hα-helixtrans-61.6-37.3178.4-72.3171.8173.2155.61.6111.6Y207 D209 T245 L246 L247 K252 T253 D284Y207-R249 HydrophobicContact CD1-CB 3.98Å; Y207-R249 HydrophobicContact CD1-CG 4.26Å; Y207-R249 HydrophobicContact CD2-CB 3.73Å; Y207-R249 HydrophobicContact CE1-CB 4.4Å; Y207-R249 HydrophobicContact CE2-CB 4.21Å; Y207-R249 HydrophobicContact CG-CB 3.63Å; Y207-R249 HydrophobicContact CG-CG 4.28Å; Y207-R249 PolarHBondContact O-NH1 3.49Å; D209-R249 IonicContact OD1-CZ 2.64Å; D209-R249 IonicContact OD1-NH1 3.39Å; D209-R249 PolarHBondContact OD1-NH1 2.92Å; D209-R249 IonicContact OD1-NH2 2.71Å; D209-R249 PolarHBondContact OD1-NH2 2.83Å; T245-R249 WeakPolarHBondContact O-CB 3.27Å; T245-R249 WeakPolarHBondContact O-CG 3.33Å; T245-R249 PolarHBondContact O-N 3.39Å; L246-R249 PolarHBondContact O-N 3.02Å; L247-R249 PolarHBondContact O-N 2.91Å; R249-K252 PolarHBondContact O-N 3.19Å; R249-T253 WeakPolarHBondContact O-CB 3.45Å; R249-T253 PolarHBondContact O-N 2.69Å; R249-T253 PolarHBondContact O-OG1 2.98Å; R249-D284 IonicContact CZ-OD1 3.17Å; R249-D284 IonicContact CZ-OD2 3.89Å; R249-D284 IonicContact NE-OD1 3.87Å; R249-D284 PolarHBondContact NE-OD1 3.47Å; R249-D284 IonicContact NE-OD2 3.45Å; R249-D284 PolarHBondContact NE-OD2 3.42Å; R249-D284 IonicContact NH2-OD1 2.86Å; R249-D284 IonicContact NH2-OD2 3.97Å; R249-D284 PolarHBondContact NH2-OD2 2.95Å
250S94.2Very high92.8Very high0 Ų017.7 Ų17.70%010%0.1CC..Hα-helixtrans-69.5-42178.6-53.30000111.6Y109 F204 L246 L247 L248 T253 I254Y109-S250 WeakPolarHBondContact OH-CB 3.46Å; Y109-S250 PolarHBondContact OH-OG 3.39Å; F204-S250 WeakPolarHBondContact CD1-OG 3.35Å; F204-S250 WeakPolarHBondContact CG-OG 3.26Å; L246-S250 VanDerWaalsContact O-CB 3.31Å; L246-S250 WeakPolarHBondContact O-CB 3.16Å; L246-S250 PolarHBondContact O-N 3.16Å; L246-S250 PolarHBondContact O-OG 3.13Å; L247-S250 PolarHBondContact O-N 2.97Å; L248-S250 VanDerWaalsContact C-N 3.26Å; L248-S250 PolarHBondContact O-N 2.8Å; S250-T253 PolarHBondContact O-N 3.21Å; S250-I254 WeakPolarHBondContact O-CG2 3.32Å; S250-I254 PolarHBondContact O-N 3.38Å
251C96.7Very high93.2Very high0 Ų017.5 Ų17.50%010%0.099CC..Hα-helixtrans-60.5-44.6171.6-71.50000112.2Y116 L247 L248 T253 I254 T255 L288 F346Y116-C251 HydrophobicContact CD1-CB 3.72Å; Y116-C251 VanDerWaalsContact CD1-SG 3.56Å; Y116-C251 HydrophobicContact CD2-CB 4.25Å; Y116-C251 HydrophobicContact CE1-CB 3.44Å; Y116-C251 VanDerWaalsContact CE1-CB 3.44Å; Y116-C251 WeakPolarHBondContact CE1-O 3.14Å; Y116-C251 HydrophobicContact CE2-CB 4.01Å; Y116-C251 HydrophobicContact CG-CB 4.12Å; Y116-C251 VanDerWaalsContact CG-SG 3.53Å; L247-C251 WeakPolarHBondContact O-CB 3.49Å; L247-C251 PolarHBondContact O-N 2.68Å; L247-C251 PolarHBondContact O-SG 2.83Å; L248-C251 PolarHBondContact O-N 3.29Å; C251-T253 VanDerWaalsContact C-N 3.3Å; C251-T253 PolarHBondContact O-N 3.42Å; C251-I254 WeakPolarHBondContact O-CG2 3.28Å; C251-T255 VanDerWaalsContact O-CB 3.23Å; C251-T255 WeakPolarHBondContact O-CB 3.37Å; C251-T255 PolarHBondContact O-N 2.99Å; C251-T255 PolarHBondContact O-OG1 3.27Å; C251-T255 VanDerWaalsContact O-OG1 3.12Å; C251-L288 HydrophobicContact CB-CD1 3.95Å; C251-F346 HydrophobicContact CB-CE1 4.3Å; C251-F346 HydrophobicContact CB-CZ 4.31Å
252K95.9Very high93.6Very high13 Ų1313.8 Ų13.86%0.0578%0.075CC..Hα-helixtrans-57.4-44.8173.7-74.1179.4173.5-178.70111.8L248 R249 T255 H256 V273 S283 D284 R286 L288L248-K252 WeakPolarHBondContact O-CG 3.08Å; L248-K252 PolarHBondContact O-N 3.45Å; R249-K252 PolarHBondContact O-N 3.19Å; K252-T255 PolarHBondContact O-N 3.33Å; K252-H256 VanDerWaalsContact O-CB 3.31Å; K252-H256 WeakPolarHBondContact O-CB 3.11Å; K252-H256 PolarHBondContact O-N 3.5Å; K252-V273 HydrophobicContact CB-CG2 4.36Å; K252-S283 PolarHBondContact NZ-O 3.17Å; K252-D284 PolarHBondContact NZ-O 3.47Å; K252-R286 WeakPolarHBondContact CE-O 3.5Å; K252-R286 PolarHBondContact NZ-O 2.59Å; K252-L288 HydrophobicContact CB-CD1 4.35Å; K252-L288 HydrophobicContact CG-CD1 3.54Å
253T92.7Very high94Very high6 Ų612.4 Ų12.44%0.0377%0.071CC..Hα-helixtrans-67.9-50.8-176.1-54.20000111.6F202 F204 Y207 R249 S250 C251 T255 H256 E257F202-T253 HydrophobicContact CB-CG2 3.89Å; F202-T253 HydrophobicContact CG-CG2 4.37Å; F204-T253 HydrophobicContact CE1-CG2 4.33Å; Y207-T253 HydrophobicContact CE2-CG2 4.44Å; Y207-T253 WeakPolarHBondContact CE2-OG1 3.47Å; Y207-T253 VanDerWaalsContact CZ-OG1 3.25Å; Y207-T253 PolarHBondContact OH-OG1 2.98Å; R249-T253 WeakPolarHBondContact O-CB 3.45Å; R249-T253 PolarHBondContact O-N 2.69Å; R249-T253 PolarHBondContact O-OG1 2.98Å; S250-T253 PolarHBondContact O-N 3.21Å; C251-T253 VanDerWaalsContact C-N 3.3Å; C251-T253 PolarHBondContact O-N 3.42Å; T253-T255 PolarHBondContact O-N 3.15Å; T253-H256 PolarHBondContact O-N 3.27Å; T253-E257 HydrophobicContact CG2-CG 4.16Å; T253-E257 WeakPolarHBondContact O-CB 3.42Å; T253-E257 WeakPolarHBondContact O-CG 3.48Å; T253-E257 PolarHBondContact O-N 2.77Å
254I93.7Very high94.2Very high0 Ų010 Ų100%06%0.056CC..Hα-helixtrans-61.5-36.7179.2-164168.4000110.9I93 Y116 C117 S250 C251 T258I93-I254 HydrophobicContact CD1-CD1 3.79Å; I93-I254 HydrophobicContact CG1-CD1 4.44Å; Y116-I254 HydrophobicContact CD1-CG2 4.04Å; Y116-I254 HydrophobicContact CE1-CG2 4.06Å; C117-I254 HydrophobicContact CB-CD1 4.1Å; S250-I254 WeakPolarHBondContact O-CG2 3.32Å; S250-I254 PolarHBondContact O-N 3.38Å; C251-I254 WeakPolarHBondContact O-CG2 3.28Å; I254-T258 WeakPolarHBondContact O-CB 3.36Å; I254-T258 PolarHBondContact O-N 2.91Å; I254-T258 PolarHBondContact O-OG1 2.71Å
255T95.9Very high94.3Very high1 Ų114.3 Ų14.31%0.0067%0.073CC..Hα-helixtrans-62.7-52.8173.2-77.50000112.4Y116 F120 C251 K252 T253 E257 G259 V273Y116-T255 VanDerWaalsContact CE1-OG1 3.24Å; Y116-T255 WeakPolarHBondContact CE1-OG1 3.21Å; Y116-T255 PolarHBondContact OH-OG1 3.08Å; F120-T255 HydrophobicContact CD1-CG2 4.1Å; F120-T255 HydrophobicContact CD2-CG2 4.19Å; F120-T255 WeakPolarHBondContact CD2-OG1 3.4Å; F120-T255 HydrophobicContact CE1-CG2 3.44Å; F120-T255 VanDerWaalsContact CE1-CG2 3.44Å; F120-T255 HydrophobicContact CE2-CG2 3.51Å; F120-T255 HydrophobicContact CG-CG2 4.45Å; F120-T255 HydrophobicContact CZ-CG2 3.09Å; C251-T255 VanDerWaalsContact O-CB 3.23Å; C251-T255 WeakPolarHBondContact O-CB 3.37Å; C251-T255 PolarHBondContact O-N 2.99Å; C251-T255 PolarHBondContact O-OG1 3.27Å; C251-T255 VanDerWaalsContact O-OG1 3.12Å; K252-T255 PolarHBondContact O-N 3.33Å; T253-T255 PolarHBondContact O-N 3.15Å; T255-E257 VanDerWaalsContact C-N 3.35Å; T255-E257 PolarHBondContact O-N 3.39Å; T255-G259 PolarHBondContact O-N 3.29Å; T255-V273 HydrophobicContact CG2-CB 4.18Å; T255-V273 HydrophobicContact CG2-CG1 3.51Å; T255-V273 HydrophobicContact CG2-CG2 3.64Å
256H94Very high94.4Very high23 Ų2313.9 Ų13.911%0.1067%0.067CC..Hα-helixtrans-56.8-52-178.1-178.8100.3000110.7K252 T253 G259 H260 H266 V273 M274 Q275K252-H256 VanDerWaalsContact O-CB 3.31Å; K252-H256 WeakPolarHBondContact O-CB 3.11Å; K252-H256 PolarHBondContact O-N 3.5Å; T253-H256 PolarHBondContact O-N 3.27Å; H256-G259 PolarHBondContact O-N 3.41Å; H256-H260 AromaticContact CD2-CD2 3.86Å; H256-H260 AromaticContact CD2-NE2 3.46Å; H256-H260 PolarHBondContact CD2-NE2 3.28Å; H256-H260 AromaticContact NE2-CD2 4Å; H256-H260 AromaticContact NE2-CE1 3.9Å; H256-H260 AromaticContact NE2-NE2 3.12Å; H256-H260 PolarHBondContact NE2-NE2 3.33Å; H256-H260 VanDerWaalsContact NE2-NE2 3.12Å; H256-H260 PolarHBondContact O-N 3.23Å; H256-H266 AromaticContact CE1-CD2 3.6Å; H256-H266 AromaticContact CE1-NE2 3.8Å; H256-H266 AromaticContact NE2-CD2 3.67Å; H256-H266 AromaticContact NE2-NE2 3.49Å; H256-H266 PolarHBondContact NE2-NE2 2.95Å; H256-V273 PolarHBondContact ND1-O 3.41Å; H256-M274 VanDerWaalsContact O-CE 3.25Å; H256-M274 WeakPolarHBondContact O-CE 3.41Å; H256-M274 VanDerWaalsContact O-SD 3.41Å; H256-Q275 PolarHBondContact CE1-O 3.49Å; H256-Q275 VanDerWaalsContact CE1-O 3.26Å
257E90.9Very high94.6Very high25 Ų2513.9 Ų13.912%0.1177%0.067CC..Hα-helixtrans-75.9-37.6-171-60.6-74.7172.100112.5F202 T253 T255 G259 H260F202-E257 HydrophobicContact CD1-CB 3.64Å; F202-E257 HydrophobicContact CD1-CG 3.33Å; F202-E257 HydrophobicContact CD2-CB 4.05Å; F202-E257 HydrophobicContact CD2-CG 4.18Å; F202-E257 HydrophobicContact CE1-CB 3.17Å; F202-E257 HydrophobicContact CE1-CG 3.42Å; F202-E257 VanDerWaalsContact CE1-CG 3.42Å; F202-E257 WeakPolarHBondContact CE1-OE2 3.46Å; F202-E257 HydrophobicContact CE2-CB 3.55Å; F202-E257 HydrophobicContact CE2-CG 4.18Å; F202-E257 HydrophobicContact CG-CB 4.09Å; F202-E257 HydrophobicContact CG-CG 3.77Å; F202-E257 HydrophobicContact CZ-CB 3.11Å; F202-E257 HydrophobicContact CZ-CG 3.86Å; T253-E257 HydrophobicContact CG2-CG 4.16Å; T253-E257 WeakPolarHBondContact O-CB 3.42Å; T253-E257 WeakPolarHBondContact O-CG 3.48Å; T253-E257 PolarHBondContact O-N 2.77Å; T255-E257 VanDerWaalsContact C-N 3.35Å; T255-E257 PolarHBondContact O-N 3.39Å; E257-G259 VanDerWaalsContact C-N 3.27Å; E257-G259 PolarHBondContact O-N 3.45Å; E257-H260 WeakPolarHBondContact O-CB 3.47Å; E257-H260 PolarHBondContact O-N 2.82Å; E257-H260 IonicContact OE2-CD2 2.71Å
258T93.6Very high94.7Very high0 Ų015 Ų150%07%0.072CC..Hα-helixtrans-67.7-32.3172.1-540000110.6I91 F121 I254 H260 M261 F262I91-T258 HydrophobicContact CD1-CG2 3.91Å; F121-T258 HydrophobicContact CD1-CG2 4.39Å; F121-T258 HydrophobicContact CD2-CG2 3.9Å; F121-T258 HydrophobicContact CE1-CG2 4Å; F121-T258 VanDerWaalsContact CE2-CB 3.49Å; F121-T258 HydrophobicContact CE2-CG2 3.47Å; F121-T258 VanDerWaalsContact CE2-CG2 3.47Å; F121-T258 HydrophobicContact CG-CG2 4.36Å; F121-T258 VanDerWaalsContact CZ-CB 3.44Å; F121-T258 HydrophobicContact CZ-CG2 3.53Å; I254-T258 WeakPolarHBondContact O-CB 3.36Å; I254-T258 PolarHBondContact O-N 2.91Å; I254-T258 PolarHBondContact O-OG1 2.71Å; T258-H260 PolarHBondContact O-N 3.36Å; T258-M261 WeakPolarHBondContact O-CB 3.36Å; T258-M261 WeakPolarHBondContact O-CG 3.12Å; T258-M261 PolarHBondContact O-N 3.49Å; T258-F262 HydrophobicContact CG2-CE2 4.44Å; T258-F262 WeakPolarHBondContact O-CD2 3.41Å
259G95.1Very high94.7Very high2 Ų214.5 Ų14.52%0.0217%0.069CC..Hα-helixtrans-57.2-37.3172.500000112.8T255 H256 E257 M261 F262 I264T255-G259 PolarHBondContact O-N 3.29Å; H256-G259 PolarHBondContact O-N 3.41Å; E257-G259 VanDerWaalsContact C-N 3.27Å; E257-G259 PolarHBondContact O-N 3.45Å; G259-M261 PolarHBondContact O-N 2.86Å; G259-F262 PolarHBondContact O-N 2.68Å; G259-I264 WeakPolarHBondContact O-CB 3.47Å
260H93.2Very high94.8Very high20 Ų2014 Ų149%0.0937%0.067CC..Hα-helixtrans-63.3-26.4173.7-65.6-50.1000113.4L195 H256 E257 T258 F262 G263 I264 H266 M274L195-H260 HydrophobicContact CD1-CB 4.33Å; L195-H260 HydrophobicContact CD2-CB 3.43Å; L195-H260 VanDerWaalsContact CD2-CB 3.43Å; H256-H260 AromaticContact CD2-CD2 3.86Å; H256-H260 AromaticContact CD2-NE2 3.46Å; H256-H260 PolarHBondContact CD2-NE2 3.28Å; H256-H260 AromaticContact NE2-CD2 4Å; H256-H260 AromaticContact NE2-CE1 3.9Å; H256-H260 AromaticContact NE2-NE2 3.12Å; H256-H260 PolarHBondContact NE2-NE2 3.33Å; H256-H260 VanDerWaalsContact NE2-NE2 3.12Å; H256-H260 PolarHBondContact O-N 3.23Å; E257-H260 WeakPolarHBondContact O-CB 3.47Å; E257-H260 PolarHBondContact O-N 2.82Å; E257-H260 IonicContact OE2-CD2 2.71Å; T258-H260 PolarHBondContact O-N 3.36Å; H260-F262 PolarHBondContact O-N 3.34Å; H260-G263 PolarHBondContact O-N 2.78Å; H260-I264 PolarHBondContact ND1-O 3.36Å; H260-H266 AromaticContact CE1-CD2 3.75Å; H260-H266 AromaticContact NE2-CD2 3.94Å; H260-H266 AromaticContact NE2-NE2 3.82Å; H260-M274 WeakPolarHBondContact ND1-CE 3.31Å
261M93.1Very high94.9Very high2 Ų215.6 Ų15.61%0.018%0.076CC..Hα-helixtrans-62.8-24.4176.8-57-65.9113.100112.6K82 F170 C171 A193 L195 G198 T258 G259 G263K82-M261 WeakPolarHBondContact CB-O 3.36Å; F170-M261 HydrophobicContact CE1-CB 3.88Å; F170-M261 HydrophobicContact CZ-CB 4.39Å; C171-M261 HydrophobicContact CB-CB 4.06Å; C171-M261 HydrophobicContact CB-CG 3.7Å; C171-M261 HydrophobicContact CB-SD 3.84Å; A193-M261 HydrophobicContact CB-CE 3.65Å; L195-M261 HydrophobicContact CD2-CE 3.57Å; G198-M261 VanDerWaalsContact C-SD 3.51Å; G198-M261 VanDerWaalsContact CA-SD 3.6Å; T258-M261 WeakPolarHBondContact O-CB 3.36Å; T258-M261 WeakPolarHBondContact O-CG 3.12Å; T258-M261 PolarHBondContact O-N 3.49Å; G259-M261 PolarHBondContact O-N 2.86Å; M261-G263 VanDerWaalsContact C-N 3.3Å
262F94.1Very high94.9Very high1 Ų115.6 Ų15.60%0.0048%0.076CC..THydrogen-bonded Turntrans-81.8-6.8173.8-65.6-96.4000112.9F75 R81 K82 P84 F121 L124 F170 T258 G259 H260 I264 L298 A301F75-F262 VanDerWaalsContact CE2-O 3.31Å; F75-F262 WeakPolarHBondContact CE2-O 3.32Å; R81-F262 WeakPolarHBondContact CG-O 3.3Å; K82-F262 PolarHBondContact N-O 3.03Å; P84-F262 HydrophobicContact CG-CD1 4.46Å; P84-F262 HydrophobicContact CG-CE1 3.62Å; P84-F262 HydrophobicContact CG-CZ 4.26Å; F121-F262 HydrophobicContact CD1-CD2 4.46Å; F121-F262 AromaticContact CD1-CE2 3.47Å; F121-F262 HydrophobicContact CD1-CE2 3.47Å; F121-F262 VanDerWaalsContact CD1-CE2 3.47Å; F121-F262 AromaticContact CD1-CZ 3.81Å; F121-F262 HydrophobicContact CD1-CZ 3.81Å; F121-F262 HydrophobicContact CE1-CD2 4.22Å; F121-F262 AromaticContact CE1-CE2 3.59Å; F121-F262 HydrophobicContact CE1-CE2 3.59Å; F121-F262 HydrophobicContact CE1-CZ 4.37Å; F121-F262 HydrophobicContact CG-CE2 4.44Å; L124-F262 HydrophobicContact CD1-CZ 4.3Å; L124-F262 HydrophobicContact CD2-CZ 4Å; F170-F262 HydrophobicContact CD1-CZ 4.38Å; F170-F262 HydrophobicContact CE1-CD1 4.2Å; F170-F262 AromaticContact CE1-CD2 3.95Å; F170-F262 HydrophobicContact CE1-CD2 3.95Å; F170-F262 AromaticContact CE1-CE1 3.91Å; F170-F262 HydrophobicContact CE1-CE1 3.91Å; F170-F262 AromaticContact CE1-CE2 3.6Å; F170-F262 HydrophobicContact CE1-CE2 3.6Å; F170-F262 HydrophobicContact CE1-CG 4.23Å; F170-F262 AromaticContact CE1-CZ 3.59Å; F170-F262 HydrophobicContact CE1-CZ 3.59Å; F170-F262 AromaticContact CZ-CD1 3.75Å; F170-F262 HydrophobicContact CZ-CD1 3.75Å; F170-F262 HydrophobicContact CZ-CD2 4.14Å; F170-F262 AromaticContact CZ-CE1 3.77Å; F170-F262 HydrophobicContact CZ-CE1 3.77Å; F170-F262 HydrophobicContact CZ-CE2 4.13Å; F170-F262 AromaticContact CZ-CG 3.95Å; F170-F262 HydrophobicContact CZ-CG 3.95Å; F170-F262 AromaticContact CZ-CZ 3.95Å; F170-F262 HydrophobicContact CZ-CZ 3.95Å; T258-F262 HydrophobicContact CG2-CE2 4.44Å; T258-F262 WeakPolarHBondContact O-CD2 3.41Å; G259-F262 PolarHBondContact O-N 2.68Å; H260-F262 PolarHBondContact O-N 3.34Å; F262-I264 HydrophobicContact CB-CD1 4.32Å; F262-I264 HydrophobicContact CB-CG1 4.19Å; F262-L298 HydrophobicContact CD1-CD1 3.88Å; F262-L298 HydrophobicContact CD2-CD1 3.88Å; F262-L298 HydrophobicContact CE1-CD1 3.85Å; F262-L298 HydrophobicContact CE2-CD1 3.88Å; F262-L298 HydrophobicContact CG-CD1 3.88Å; F262-L298 HydrophobicContact CZ-CD1 3.87Å; F262-A301 HydrophobicContact CD1-CB 3.76Å; F262-A301 HydrophobicContact CE1-CB 4.44Å
263G94.1Very high95Very high12 Ų1215.3 Ų15.312%0.1248%0.075CC..THydrogen-bonded Turntrans88.411.8-17300000114.3Q70 H260 M261 K265Q70-G263 PolarHBondContact NE2-O 2.89Å; H260-G263 PolarHBondContact O-N 2.78Å; M261-G263 VanDerWaalsContact C-N 3.3Å; G263-K265 PolarHBondContact O-N 2.71Å
264I95.6Very high95.3Very high1 Ų115 Ų151%0.0057%0.074CC..  trans-74.9120.6175.7-56174.5000108.2F75 G259 H260 F262 M274 K297 L298F75-I264 HydrophobicContact CD2-CG1 4.27Å; F75-I264 HydrophobicContact CE2-CG1 3.7Å; F75-I264 HydrophobicContact CZ-CG1 4.29Å; G259-I264 WeakPolarHBondContact O-CB 3.47Å; H260-I264 PolarHBondContact ND1-O 3.36Å; F262-I264 HydrophobicContact CB-CD1 4.32Å; F262-I264 HydrophobicContact CB-CG1 4.19Å; I264-M274 HydrophobicContact CB-CE 4.13Å; I264-M274 HydrophobicContact CG2-CB 4.46Å; I264-M274 HydrophobicContact CG2-CE 3.93Å; I264-M274 HydrophobicContact CG2-CG 4.01Å; I264-M274 HydrophobicContact CG2-SD 4.5Å; I264-K297 HydrophobicContact CD1-CB 4.28Å; I264-K297 HydrophobicContact CG1-CB 4.24Å; I264-K297 HydrophobicContact CG1-CD 4.44Å; I264-K297 HydrophobicContact CG2-CD 4.28Å; I264-L298 HydrophobicContact CD1-CB 4.07Å; I264-L298 HydrophobicContact CD1-CD1 4.41Å
265K95.1Very high95.4Very high110 Ų11015.1 Ų15.148%0.4787%0.074SC..  trans-83.9174.5175.8-67.2178-176.5175.90111.5Q70 G263 C267Q70-K265 HydrophobicContact CB-CB 4.05Å; Q70-K265 HydrophobicContact CB-CD 4.24Å; Q70-K265 HydrophobicContact CG-CD 4.35Å; G263-K265 PolarHBondContact O-N 2.71Å; K265-C267 PolarHBondContact O-N 3.01Å
266H95.8Very high95.2Very high35 Ų3515.1 Ų15.116%0.1627%0.074CC..  trans-52.1132.9172.5-70.3144.7000111.9W61 E67 H256 H260 M274 G276W61-H266 AromaticContact CE2-CE1 3.67Å; W61-H266 AromaticContact CE2-ND1 3.69Å; W61-H266 AromaticContact CZ2-CE1 3.36Å; W61-H266 WeakPolarHBondContact CZ2-CE1 3.36Å; W61-H266 AromaticContact CZ2-ND1 3.65Å; W61-H266 AromaticContact NE1-CE1 3.88Å; W61-H266 AromaticContact NE1-ND1 3.44Å; W61-H266 PolarHBondContact NE1-ND1 3.42Å; E67-H266 IonicContact OE1-CE1 3.98Å; E67-H266 IonicContact OE1-CG 3.36Å; E67-H266 IonicContact OE1-ND1 3.34Å; E67-H266 PolarHBondContact OE1-ND1 3.35Å; E67-H266 WeakPolarHBondContact OE2-CB 3.49Å; E67-H266 IonicContact OE2-CG 3.57Å; E67-H266 IonicContact OE2-ND1 3.72Å; E67-H266 PolarHBondContact OE2-ND1 3.37Å; H256-H266 AromaticContact CE1-CD2 3.6Å; H256-H266 AromaticContact CE1-NE2 3.8Å; H256-H266 AromaticContact NE2-CD2 3.67Å; H256-H266 AromaticContact NE2-NE2 3.49Å; H256-H266 PolarHBondContact NE2-NE2 2.95Å; H260-H266 AromaticContact CE1-CD2 3.75Å; H260-H266 AromaticContact NE2-CD2 3.94Å; H260-H266 AromaticContact NE2-NE2 3.82Å; H266-M274 CarbonylContact C-O 3.55Å; H266-M274 WeakPolarHBondContact CA-O 3.18Å; H266-G276 PolarHBondContact CD2-N 3.26Å
267C97.6Very high95Very high3 Ų315.3 Ų15.32%0.028%0.078CC..  trans-80.6132.1-179.4-169.50000110.6K265 C272 M274 Q275 C294K265-C267 PolarHBondContact O-N 3.01Å; C267-C272 HydrophobicContact CB-CB 3.84Å; C267-M274 HydrophobicContact CB-CB 4.09Å; C267-M274 PolarHBondContact N-O 2.86Å; C267-Q275 HydrophobicContact CB-CG 4.05Å; C267-Q275 WeakPolarHBondContact O-CG 2.99Å; C267-C294 VanDerWaalsContact SG-SG 3.67Å
268Q96.7Very high94.8Very high23 Ų2317.3 Ų17.311%0.1079%0.089CC..  trans-12311.1174.2-62.1-165.21.300113.5H6 I53 E67 P69H6-Q268 PolarHBondContact NE2-O 2.85Å; I53-Q268 VanDerWaalsContact CD1-C 3.47Å; I53-Q268 WeakPolarHBondContact CD1-O 3.28Å; E67-Q268 VanDerWaalsContact C-NE2 3.31Å; E67-Q268 VanDerWaalsContact CB-NE2 3.31Å; E67-Q268 VanDerWaalsContact O-CD 3.23Å; E67-Q268 PolarHBondContact O-NE2 3.37Å; E67-Q268 PolarHBondContact O-OE1 2.87Å; P69-Q268 HydrophobicContact CB-CB 4.19Å; P69-Q268 HydrophobicContact CG-CB 4.12Å
269W96.8Very high94.3Very high14 Ų1419.3 Ų19.35%0.05310%0.099CC..SBendtrans-90.4-44-172.9-65.6111.4000113.4H6 K10 L11 A14 P69 Q70 D71 I293H6-W269 PolarHBondContact CD2-O 3.34Å; K10-W269 HydrophobicContact CD-CZ3 4.05Å; K10-W269 HydrophobicContact CG-CH2 4.33Å; K10-W269 HydrophobicContact CG-CZ3 3.91Å; L11-W269 HydrophobicContact CD2-CE3 4.14Å; A14-W269 HydrophobicContact CB-CD2 3.97Å; A14-W269 HydrophobicContact CB-CE3 4.02Å; A14-W269 HydrophobicContact CB-CH2 3.58Å; A14-W269 HydrophobicContact CB-CZ2 3.53Å; A14-W269 HydrophobicContact CB-CZ3 3.83Å; P69-W269 HydrophobicContact CB-CD2 4.43Å; P69-W269 HydrophobicContact CB-CH2 4.15Å; P69-W269 HydrophobicContact CB-CZ2 3.53Å; Q70-W269 PolarHBondContact O-NE1 3.28Å; D71-W269 HydrophobicContact CB-CZ2 3.89Å; W269-I293 HydrophobicContact CB-CD1 3.58Å; W269-I293 HydrophobicContact CD2-CD1 3.84Å; W269-I293 HydrophobicContact CE3-CD1 4.4Å; W269-I293 HydrophobicContact CG-CD1 3.44Å; W269-I293 VanDerWaalsContact CG-CD1 3.44Å
270M95.9Very high93.9Very high2 Ų219.8 Ų19.81%0.0110%0.101CC..SBendtrans-165.9180-178.665.2-16974.500109.4L11 G40 F50 Q51 C272 C291 P292 I293L11-M270 HydrophobicContact CD2-CE 3.82Å; G40-M270 VanDerWaalsContact O-CE 3.25Å; G40-M270 WeakPolarHBondContact O-CE 3.48Å; F50-M270 HydrophobicContact CB-SD 4.06Å; F50-M270 HydrophobicContact CG-SD 4.45Å; Q51-M270 WeakPolarHBondContact O-CB 3.37Å; M270-C272 PolarHBondContact O-N 2.63Å; M270-C291 HydrophobicContact CG-CB 3.25Å; M270-C291 HydrophobicContact SD-CB 3.65Å; M270-P292 VanDerWaalsContact SD-CD 3.56Å; M270-I293 HydrophobicContact CE-CD1 4.22Å
271N96.1Very high93.7Very high35 Ų3523.9 Ų23.919%0.18712%0.12CC..SBendtrans-57.2125.8177.2-87.2-4.9000111Q51 P52 Q275 P287Q51-N271 HydrophobicContact CB-CB 4.3Å; Q51-N271 WeakPolarHBondContact O-CB 3.34Å; Q51-N271 PolarHBondContact O-N 3.09Å; P52-N271 PolarHBondContact O-ND2 3.46Å; P52-N271 PolarHBondContact O-OD1 2.8Å; N271-Q275 VanDerWaalsContact CA-OE1 3.29Å; N271-P287 HydrophobicContact CB-CG 4.27Å
272C98.1Very high93.7Very high0 Ų023.8 Ų23.80%012%0.12CC..  trans-159.1145.2-172.3-176.20000110C267 M270 M274 Q275 C291C267-C272 HydrophobicContact CB-CB 3.84Å; M270-C272 PolarHBondContact O-N 2.63Å; C272-M274 PolarHBondContact O-N 3.12Å; C272-M274 PolarHBondContact SG-N 3.01Å; C272-M274 VanDerWaalsContact SG-N 3.41Å; C272-Q275 HydrophobicContact CB-CG 4.1Å; C272-Q275 WeakPolarHBondContact O-CB 3.4Å; C272-Q275 VanDerWaalsContact O-CG 3.23Å; C272-Q275 WeakPolarHBondContact O-CG 3.29Å; C272-Q275 PolarHBondContact O-N 2.82Å; C272-Q275 VanDerWaalsContact O-N 3.14Å; C272-Q275 PolarHBondContact O-OE1 2.76Å; C272-C291 HydrophobicContact CB-CB 3.92Å; C272-C291 PolarHBondContact SG-N 2.62Å; C272-C291 VanDerWaalsContact SG-N 3.39Å
273V97.6Very high93.5Very high6 Ų624.5 Ų24.54%0.03612%0.124CC..THydrogen-bonded Turntrans-60.6-25.9172.467.60000112.8F120 K252 T255 H256 Q275 P287 D289 L290F120-V273 HydrophobicContact CZ-CG1 4.36Å; K252-V273 HydrophobicContact CB-CG2 4.36Å; T255-V273 HydrophobicContact CG2-CB 4.18Å; T255-V273 HydrophobicContact CG2-CG1 3.51Å; T255-V273 HydrophobicContact CG2-CG2 3.64Å; H256-V273 PolarHBondContact ND1-O 3.41Å; V273-Q275 PolarHBondContact O-N 2.73Å; V273-P287 WeakPolarHBondContact CB-O 3.46Å; V273-D289 PolarHBondContact N-O 2.96Å; V273-L290 HydrophobicContact CG1-CD2 3.63Å; V273-L290 HydrophobicContact CG1-CG 4.19Å
274M97.4Very high93.5Very high1 Ų126.6 Ų26.61%0.00513%0.133CC..THydrogen-bonded Turntrans-798.6177-63.5-59.8-52.500113.7H256 H260 I264 H266 C267 C272 L290 C294H256-M274 VanDerWaalsContact O-CE 3.25Å; H256-M274 WeakPolarHBondContact O-CE 3.41Å; H256-M274 VanDerWaalsContact O-SD 3.41Å; H260-M274 WeakPolarHBondContact ND1-CE 3.31Å; I264-M274 HydrophobicContact CB-CE 4.13Å; I264-M274 HydrophobicContact CG2-CB 4.46Å; I264-M274 HydrophobicContact CG2-CE 3.93Å; I264-M274 HydrophobicContact CG2-CG 4.01Å; I264-M274 HydrophobicContact CG2-SD 4.5Å; H266-M274 CarbonylContact C-O 3.55Å; H266-M274 WeakPolarHBondContact CA-O 3.18Å; C267-M274 HydrophobicContact CB-CB 4.09Å; C267-M274 PolarHBondContact N-O 2.86Å; C272-M274 PolarHBondContact O-N 3.12Å; C272-M274 PolarHBondContact SG-N 3.01Å; C272-M274 VanDerWaalsContact SG-N 3.41Å; M274-L290 HydrophobicContact CG-CD2 3.46Å; M274-L290 VanDerWaalsContact CG-CD2 3.46Å; M274-L290 HydrophobicContact SD-CD2 4.39Å; M274-C294 HydrophobicContact CG-CB 4.5Å
275Q96Very high93.4Very high1 Ų130.6 Ų30.61%0.00515%0.148CC..SBendtrans-74.9136.1175.2-66.8-178.2-79.600110.7I53 H256 C267 N271 C272 V273I53-Q275 VanDerWaalsContact CD1-NE2 3.34Å; H256-Q275 PolarHBondContact CE1-O 3.49Å; H256-Q275 VanDerWaalsContact CE1-O 3.26Å; C267-Q275 HydrophobicContact CB-CG 4.05Å; C267-Q275 WeakPolarHBondContact O-CG 2.99Å; N271-Q275 VanDerWaalsContact CA-OE1 3.29Å; C272-Q275 HydrophobicContact CB-CG 4.1Å; C272-Q275 WeakPolarHBondContact O-CB 3.4Å; C272-Q275 VanDerWaalsContact O-CG 3.23Å; C272-Q275 WeakPolarHBondContact O-CG 3.29Å; C272-Q275 PolarHBondContact O-N 2.82Å; C272-Q275 VanDerWaalsContact O-N 3.14Å; C272-Q275 PolarHBondContact O-OE1 2.76Å; V273-Q275 PolarHBondContact O-N 2.73Å
276G92.1Very high93.3Very high1 Ų125.9 Ų25.91%0.0113%0.127CC..  trans-60.1151.6170.200000111.1W61 H266W61-G276 VanDerWaalsContact CB-C 3.48Å; W61-G276 WeakPolarHBondContact CB-O 3.34Å; W61-G276 VanDerWaalsContact CG-C 3.46Å; H266-G276 PolarHBondContact CD2-N 3.26Å
277S90.4Very high93.3Very high28 Ų2826.4 Ų26.420%0.19613%0.134CC..  trans-141.3133179.5-620000110.3E282S277-E282 WeakPolarHBondContact CA-OE2 3.39Å
278N85.7Confident93.3Very high66 Ų6626.4 Ų26.435%0.35313%0.133SC..SBendtrans-92.9-23.1-179.6-164.235.2000112.1S59 W61 E282S59-N278 WeakPolarHBondContact O-CB 3.37Å; S59-N278 PolarHBondContact O-ND2 3.21Å; W61-N278 HydrophobicContact CE3-CB 4.37Å; N278-E282 PolarHBondContact N-OE2 3.32Å
279H84.5Confident93.3Very high42 Ų4225.6 Ų25.619%0.19413%0.13CC..SBendtrans-150.3169.4-179.460.293.6000112.3D60 E281 E282 S283D60-H279 IonicContact OD1-NE2 3.25Å; H279-E281 IonicContact CE1-OE2 3.45Å; H279-E281 IonicContact CG-OE2 3.24Å; H279-E281 IonicContact ND1-OE2 3.44Å; H279-E281 PolarHBondContact ND1-OE2 3.18Å; H279-E281 PolarHBondContact O-N 3.12Å; H279-E282 PolarHBondContact ND1-N 2.65Å; H279-E282 WeakPolarHBondContact O-CB 3.25Å; H279-E282 PolarHBondContact O-N 3.05Å; H279-S283 PolarHBondContact O-N 2.69Å; H279-S283 VanDerWaalsContact O-N 3.15Å
280L85.8Confident93.4Very high12 Ų1225.1 Ų25.16%0.06313%0.129CC..Hα-helixtrans-64.2-44.6-170.618054.9000112.6Y207 E282 S283 D284Y207-L280 HydrophobicContact CD1-CD1 3.42Å; Y207-L280 VanDerWaalsContact CD1-CD1 3.42Å; Y207-L280 HydrophobicContact CE1-CD1 3.64Å; L280-E282 PolarHBondContact O-N 3.28Å; L280-S283 CarbonylContact O-C 3.59Å; L280-S283 WeakPolarHBondContact O-CB 3.24Å; L280-S283 PolarHBondContact O-N 2.8Å; L280-S283 VanDerWaalsContact O-N 3.08Å; L280-D284 PolarHBondContact O-N 3Å
281E90.2Very high93.5Very high107 Ų10725 Ų2550%0.513%0.128SC..Hα-helixtrans-63-31.5-179.2-56.776.1-17100111.2H279 R285H279-E281 IonicContact CE1-OE2 3.45Å; H279-E281 IonicContact CG-OE2 3.24Å; H279-E281 IonicContact ND1-OE2 3.44Å; H279-E281 PolarHBondContact ND1-OE2 3.18Å; H279-E281 PolarHBondContact O-N 3.12Å; E281-R285 WeakPolarHBondContact O-CG 3.44Å; E281-R285 PolarHBondContact O-N 3.49Å; E281-R285 PolarHBondContact O-NH1 3.05Å
282E91.9Very high93.6Very high0 Ų023.4 Ų23.40%012%0.119CC..Hα-helixtrans-68.5-46.6172.8-174.9179.1-163.900111.5D60 W61 S277 N278 H279 L280 D284 R285 R286D60-E282 WeakPolarHBondContact CA-OE1 3.32Å; W61-E282 PolarHBondContact N-OE1 3.37Å; W61-E282 PolarHBondContact N-OE2 2.8Å; S277-E282 WeakPolarHBondContact CA-OE2 3.39Å; N278-E282 PolarHBondContact N-OE2 3.32Å; H279-E282 PolarHBondContact ND1-N 2.65Å; H279-E282 WeakPolarHBondContact O-CB 3.25Å; H279-E282 PolarHBondContact O-N 3.05Å; L280-E282 PolarHBondContact O-N 3.28Å; E282-D284 VanDerWaalsContact C-N 3.3Å; E282-D284 PolarHBondContact O-N 3.34Å; E282-R285 PolarHBondContact O-N 3.01Å; E282-R286 WeakPolarHBondContact O-CG 3.36Å; E282-R286 IonicContact OE1-CZ 2.81Å; E282-R286 IonicContact OE1-NH2 3.9Å; E282-R286 PolarHBondContact OE1-NH2 3.12Å
283S90.8Very high93.6Very high15 Ų1523.5 Ų23.511%0.10512%0.12CC..Hα-helixtrans-60.5-37.6175.8-174.50000112.5K252 H279 L280 R285 R286K252-S283 PolarHBondContact NZ-O 3.17Å; H279-S283 PolarHBondContact O-N 2.69Å; H279-S283 VanDerWaalsContact O-N 3.15Å; L280-S283 CarbonylContact O-C 3.59Å; L280-S283 WeakPolarHBondContact O-CB 3.24Å; L280-S283 PolarHBondContact O-N 2.8Å; L280-S283 VanDerWaalsContact O-N 3.08Å; S283-R285 VanDerWaalsContact C-N 3.33Å; S283-R285 PolarHBondContact O-N 2.67Å; S283-R286 WeakPolarHBondContact O-CB 3.41Å; S283-R286 PolarHBondContact O-N 3.21Å
284D92.6Very high93.7Very high57 Ų5723.2 Ų23.231%0.30512%0.118SC..Hα-helixtrans-65.8-35.3179.3-78.9-15.8000112.3R249 K252 L280 E282 R286R249-D284 IonicContact CZ-OD1 3.17Å; R249-D284 IonicContact CZ-OD2 3.89Å; R249-D284 IonicContact NE-OD1 3.87Å; R249-D284 PolarHBondContact NE-OD1 3.47Å; R249-D284 IonicContact NE-OD2 3.45Å; R249-D284 PolarHBondContact NE-OD2 3.42Å; R249-D284 IonicContact NH2-OD1 2.86Å; R249-D284 IonicContact NH2-OD2 3.97Å; R249-D284 PolarHBondContact NH2-OD2 2.95Å; K252-D284 PolarHBondContact NZ-O 3.47Å; L280-D284 PolarHBondContact O-N 3Å; E282-D284 VanDerWaalsContact C-N 3.3Å; E282-D284 PolarHBondContact O-N 3.34Å; D284-R286 PolarHBondContact O-N 3.29Å
285R93.7Very high93.8Very high84 Ų8423.2 Ų23.232%0.31712%0.118SC..Hα-helixtrans-69.5-18175.6-68.3-175.3-56.8-95.116.1113.7H56 D60 E281 E282 S283H56-R285 PolarHBondContact CD2-NE 3.48Å; H56-R285 VanDerWaalsContact NE2-CD 3.33Å; H56-R285 WeakPolarHBondContact NE2-CD 3.48Å; D60-R285 IonicContact OD1-NH2 3.94Å; D60-R285 PolarHBondContact OD1-NH2 3.37Å; D60-R285 IonicContact OD2-NH2 3.5Å; D60-R285 PolarHBondContact OD2-NH2 2.9Å; E281-R285 WeakPolarHBondContact O-CG 3.44Å; E281-R285 PolarHBondContact O-N 3.49Å; E281-R285 PolarHBondContact O-NH1 3.05Å; E282-R285 PolarHBondContact O-N 3.01Å; S283-R285 VanDerWaalsContact C-N 3.33Å; S283-R285 PolarHBondContact O-N 2.67Å
286R93.9Very high93.9Very high12 Ų1223.1 Ų23.15%0.04512%0.118CC..SBendtrans-71.6145.7179-52.6-53.9-178.7-173.8-5.1110.5K252 E282 S283 D284K252-R286 WeakPolarHBondContact CE-O 3.5Å; K252-R286 PolarHBondContact NZ-O 2.59Å; E282-R286 WeakPolarHBondContact O-CG 3.36Å; E282-R286 IonicContact OE1-CZ 2.81Å; E282-R286 IonicContact OE1-NH2 3.9Å; E282-R286 PolarHBondContact OE1-NH2 3.12Å; S283-R286 WeakPolarHBondContact O-CB 3.41Å; S283-R286 PolarHBondContact O-N 3.21Å; D284-R286 PolarHBondContact O-N 3.29Å
287P96.3Very high94.2Very high46 Ų4623.2 Ų23.230%0.29912%0.118SC..  trans-68.4166.4172.731.7-35.8000110.8N271 V273 D289N271-P287 HydrophobicContact CB-CG 4.27Å; V273-P287 WeakPolarHBondContact CB-O 3.46Å; P287-D289 VanDerWaalsContact C-N 3.33Å
288L97Very high94.5Very high2 Ų222 Ų221%0.0111%0.109CC..SBendtrans-77.2-21.5171.9-173.160.6000112.7Y116 L248 C251 K252 M317 F346 S349Y116-L288 HydrophobicContact CE2-CD2 4.16Å; Y116-L288 HydrophobicContact CE2-CG 4.5Å; Y116-L288 VanDerWaalsContact OH-CD1 3.22Å; Y116-L288 WeakPolarHBondContact OH-CD1 3.48Å; Y116-L288 WeakPolarHBondContact OH-CG 3.37Å; L248-L288 HydrophobicContact CD1-CB 4.43Å; L248-L288 HydrophobicContact CD1-CD1 4.01Å; L248-L288 HydrophobicContact CD1-CD2 3.89Å; L248-L288 HydrophobicContact CD1-CG 4.34Å; C251-L288 HydrophobicContact CB-CD1 3.95Å; K252-L288 HydrophobicContact CB-CD1 4.35Å; K252-L288 HydrophobicContact CG-CD1 3.54Å; L288-M317 HydrophobicContact CD2-CE 3.62Å; L288-F346 HydrophobicContact CD2-CD1 3.6Å; L288-F346 HydrophobicContact CD2-CE1 3.61Å; L288-S349 WeakPolarHBondContact CB-OG 3.48Å
289D96.9Very high95.1Very high6 Ų620.3 Ų20.33%0.03210%0.099CC..SBendtrans-109.9168.8-171.8-83-78.4000114.3V273 P287 R309 W352V273-D289 PolarHBondContact N-O 2.96Å; P287-D289 VanDerWaalsContact C-N 3.33Å; D289-R309 IonicContact OD1-CZ 2.89Å; D289-R309 IonicContact OD1-NH1 3.29Å; D289-R309 PolarHBondContact OD1-NH1 2.88Å; D289-R309 IonicContact OD1-NH2 3.84Å; D289-R309 PolarHBondContact OD1-NH2 2.78Å; D289-W352 HydrophobicContact CB-CE3 4.13Å; D289-W352 HydrophobicContact CB-CH2 3.63Å; D289-W352 HydrophobicContact CB-CZ2 4.47Å; D289-W352 HydrophobicContact CB-CZ3 3.42Å; D289-W352 VanDerWaalsContact CB-CZ3 3.42Å
290L98.6Very high95.7Very high5 Ų519.9 Ų19.93%0.02610%0.099CC..  trans-79.9144179.1-62.4167.7000111.3F120 V273 M274 C294 L295 L298F120-L290 HydrophobicContact CE1-CD1 4.12Å; F120-L290 HydrophobicContact CE1-CG 4.33Å; F120-L290 HydrophobicContact CZ-CD1 4.24Å; F120-L290 HydrophobicContact CZ-CG 3.99Å; V273-L290 HydrophobicContact CG1-CD2 3.63Å; V273-L290 HydrophobicContact CG1-CG 4.19Å; M274-L290 HydrophobicContact CG-CD2 3.46Å; M274-L290 VanDerWaalsContact CG-CD2 3.46Å; M274-L290 HydrophobicContact SD-CD2 4.39Å; L290-C294 HydrophobicContact CB-CB 4.19Å; L290-C294 HydrophobicContact CD2-CB 3.76Å; L290-C294 HydrophobicContact CG-CB 4.45Å; L290-L295 HydrophobicContact CB-CB 4.09Å; L290-L295 HydrophobicContact CD1-CD1 4.48Å; L290-L298 HydrophobicContact CD1-CB 3.94Å; L290-L298 HydrophobicContact CD1-CD2 3.49Å; L290-L298 VanDerWaalsContact CD1-CD2 3.49Å; L290-L298 HydrophobicContact CD1-CG 4.34Å
291C98.4Very high96.1Very high0 Ų019.5 Ų19.50%010%0.098CC..  trans-69.4164.4162.573.10000111.5M270 C272 I293 C294 L295M270-C291 HydrophobicContact CG-CB 3.25Å; M270-C291 HydrophobicContact SD-CB 3.65Å; C272-C291 HydrophobicContact CB-CB 3.92Å; C272-C291 PolarHBondContact SG-N 2.62Å; C272-C291 VanDerWaalsContact SG-N 3.39Å; C291-I293 VanDerWaalsContact C-N 3.25Å; C291-I293 PolarHBondContact O-N 3.18Å; C291-I293 VanDerWaalsContact O-N 3.14Å; C291-C294 PolarHBondContact O-N 2.94Å; C291-C294 VanDerWaalsContact SG-SG 3.69Å; C291-L295 WeakPolarHBondContact O-CB 3.5Å; C291-L295 PolarHBondContact O-N 3.38Å
292P98.1Very high96.3Very high1 Ų115.5 Ų15.51%0.0069%0.086CC..Hα-helixtrans-57.1-35.7-176.1-33.744.8000114.2L15 L37 F50 M270 L295 H296L15-P292 HydrophobicContact CD1-CB 4.27Å; L37-P292 HydrophobicContact CB-CB 4.29Å; L37-P292 HydrophobicContact CD2-CB 3.81Å; L37-P292 VanDerWaalsContact O-CB 3.28Å; L37-P292 WeakPolarHBondContact O-CB 3.43Å; F50-P292 HydrophobicContact CD1-CG 3.96Å; F50-P292 HydrophobicContact CD2-CG 3.76Å; F50-P292 VanDerWaalsContact CE1-CD 3.44Å; F50-P292 HydrophobicContact CE1-CG 3.63Å; F50-P292 HydrophobicContact CE2-CG 3.45Å; F50-P292 VanDerWaalsContact CE2-CG 3.45Å; F50-P292 HydrophobicContact CG-CG 4.01Å; F50-P292 HydrophobicContact CZ-CG 3.39Å; M270-P292 VanDerWaalsContact SD-CD 3.56Å; P292-L295 PolarHBondContact O-N 3.01Å; P292-H296 WeakPolarHBondContact O-CB 3.17Å; P292-H296 PolarHBondContact O-N 3.39Å
293I98.6Very high96.4Very high2 Ų218.5 Ų18.51%0.0112%0.117CC..Hα-helixtrans-66.7-45.2178-63.8164.3000110.5L11 A14 L15 W269 M270 C291 K297L11-I293 HydrophobicContact CD2-CD1 4.39Å; A14-I293 HydrophobicContact CB-CD1 3.74Å; A14-I293 HydrophobicContact CB-CG1 4.49Å; L15-I293 HydrophobicContact CB-CG1 4.07Å; L15-I293 HydrophobicContact CD1-CG1 4.26Å; W269-I293 HydrophobicContact CB-CD1 3.58Å; W269-I293 HydrophobicContact CD2-CD1 3.84Å; W269-I293 HydrophobicContact CE3-CD1 4.4Å; W269-I293 HydrophobicContact CG-CD1 3.44Å; W269-I293 VanDerWaalsContact CG-CD1 3.44Å; M270-I293 HydrophobicContact CE-CD1 4.22Å; C291-I293 VanDerWaalsContact C-N 3.25Å; C291-I293 PolarHBondContact O-N 3.18Å; C291-I293 VanDerWaalsContact O-N 3.14Å; I293-K297 VanDerWaalsContact O-CG 3.31Å; I293-K297 WeakPolarHBondContact O-CG 3.46Å; I293-K297 PolarHBondContact O-N 2.89Å
294C98.8Very high96.7Very high0 Ų018.5 Ų18.50%011%0.114CC..Hα-helixtrans-76-30.3179-60.40000112.3C267 M274 L290 C291 K297 L298C267-C294 VanDerWaalsContact SG-SG 3.67Å; M274-C294 HydrophobicContact CG-CB 4.5Å; L290-C294 HydrophobicContact CB-CB 4.19Å; L290-C294 HydrophobicContact CD2-CB 3.76Å; L290-C294 HydrophobicContact CG-CB 4.45Å; C291-C294 PolarHBondContact O-N 2.94Å; C291-C294 VanDerWaalsContact SG-SG 3.69Å; C294-K297 PolarHBondContact O-N 3.37Å; C294-L298 WeakPolarHBondContact O-CB 3.31Å; C294-L298 PolarHBondContact O-N 3.39Å
295L98.6Very high96.9Very high0 Ų022.3 Ų22.30%013%0.128CC..Hα-helixtrans-63.3-44.5171.6-179.960.2000110.8L37 L290 C291 P292 K297 L298 Q299 F304 I306 Y310L37-L295 HydrophobicContact CD2-CB 4.42Å; L37-L295 HydrophobicContact CD2-CD2 3.92Å; L37-L295 HydrophobicContact CD2-CG 4.29Å; L290-L295 HydrophobicContact CB-CB 4.09Å; L290-L295 HydrophobicContact CD1-CD1 4.48Å; C291-L295 WeakPolarHBondContact O-CB 3.5Å; C291-L295 PolarHBondContact O-N 3.38Å; P292-L295 PolarHBondContact O-N 3.01Å; L295-K297 PolarHBondContact O-N 3Å; L295-L298 PolarHBondContact O-N 3.1Å; L295-Q299 VanDerWaalsContact O-CB 3.22Å; L295-Q299 WeakPolarHBondContact O-CB 3.49Å; L295-Q299 PolarHBondContact O-N 2.81Å; L295-F304 HydrophobicContact CD1-CE2 4.38Å; L295-F304 HydrophobicContact CD1-CZ 4.48Å; L295-I306 HydrophobicContact CD2-CD1 4.03Å; L295-I306 HydrophobicContact CD2-CG1 4.48Å; L295-I306 HydrophobicContact CD2-CG2 4.05Å; L295-I306 HydrophobicContact CG-CD1 4.27Å; L295-Y310 VanDerWaalsContact CD2-OH 3.23Å; L295-Y310 WeakPolarHBondContact CD2-OH 3.42Å
296H98.4Very high97Very high0 Ų018.3 Ų18.30%011%0.113CC..Hα-helixtrans-60.5-45.3175.5-177.637.7000111.7L15 Y26 Y29 F72 P292 L298 Q299 V300L15-H296 HydrophobicContact CD1-CB 3.97Å; L15-H296 PolarHBondContact O-CD2 2.96Å; Y26-H296 AromaticContact CD2-NE2 3.92Å; Y29-H296 AromaticContact CE2-CE1 3.55Å; Y29-H296 AromaticContact CE2-ND1 3.25Å; Y29-H296 VanDerWaalsContact CE2-ND1 3.25Å; Y29-H296 WeakPolarHBondContact CE2-ND1 3.19Å; Y29-H296 AromaticContact CZ-ND1 3.47Å; Y29-H296 PolarHBondContact OH-ND1 3.12Å; F72-H296 AromaticContact CD1-CD2 3.57Å; F72-H296 AromaticContact CD1-NE2 3.36Å; F72-H296 WeakPolarHBondContact CD1-NE2 3.19Å; F72-H296 AromaticContact CD2-CD2 3.24Å; F72-H296 WeakPolarHBondContact CD2-CD2 3.33Å; F72-H296 AromaticContact CD2-CG 3.93Å; F72-H296 AromaticContact CD2-NE2 3.64Å; F72-H296 AromaticContact CE1-CD2 3.82Å; F72-H296 AromaticContact CE1-NE2 3.18Å; F72-H296 WeakPolarHBondContact CE1-NE2 3.37Å; F72-H296 AromaticContact CE2-CD2 3.52Å; F72-H296 AromaticContact CE2-CE1 3.92Å; F72-H296 AromaticContact CE2-NE2 3.48Å; F72-H296 WeakPolarHBondContact CE2-NE2 3.3Å; F72-H296 AromaticContact CG-CD2 3.27Å; F72-H296 WeakPolarHBondContact CG-CD2 3.39Å; F72-H296 AromaticContact CG-NE2 3.59Å; F72-H296 AromaticContact CZ-CD2 3.82Å; F72-H296 AromaticContact CZ-CE1 3.73Å; F72-H296 AromaticContact CZ-NE2 3.26Å; F72-H296 VanDerWaalsContact CZ-NE2 3.26Å; F72-H296 WeakPolarHBondContact CZ-NE2 3.33Å; P292-H296 WeakPolarHBondContact O-CB 3.17Å; P292-H296 PolarHBondContact O-N 3.39Å; H296-L298 PolarHBondContact O-N 2.88Å; H296-Q299 PolarHBondContact O-N 2.68Å; H296-V300 VanDerWaalsContact CE1-CG2 3.43Å; H296-V300 WeakPolarHBondContact CE1-CG2 3.37Å; H296-V300 WeakPolarHBondContact O-CB 3.24Å; H296-V300 WeakPolarHBondContact O-CG2 3.4Å; H296-V300 PolarHBondContact O-N 3.43Å
297K98.3Very high97.2Very high2 Ų218.9 Ų18.91%0.00912%0.12CC..Hα-helixtrans-56-50174.3-68174.3-173.5178.50112.1Q70 D71 F72 F75 I264 I293 C294 L295 A301Q70-K297 PolarHBondContact O-NZ 3.22Å; D71-K297 VanDerWaalsContact O-CE 3.25Å; D71-K297 WeakPolarHBondContact O-CE 3.4Å; F72-K297 HydrophobicContact CD2-CG 3.96Å; F75-K297 HydrophobicContact CB-CD 3.79Å; F75-K297 HydrophobicContact CB-CG 3.91Å; F75-K297 HydrophobicContact CD1-CB 3.67Å; F75-K297 HydrophobicContact CD1-CD 4.16Å; F75-K297 HydrophobicContact CD1-CG 3.5Å; F75-K297 HydrophobicContact CD2-CB 4.29Å; F75-K297 HydrophobicContact CD2-CD 3.99Å; F75-K297 HydrophobicContact CD2-CG 4.21Å; F75-K297 HydrophobicContact CE1-CB 3.56Å; F75-K297 HydrophobicContact CE1-CG 3.97Å; F75-K297 WeakPolarHBondContact CE1-O 3.48Å; F75-K297 HydrophobicContact CE2-CB 4.21Å; F75-K297 HydrophobicContact CG-CB 4.02Å; F75-K297 HydrophobicContact CG-CD 3.72Å; F75-K297 HydrophobicContact CG-CG 3.61Å; F75-K297 HydrophobicContact CZ-CB 3.84Å; F75-K297 HydrophobicContact CZ-CG 4.5Å; I264-K297 HydrophobicContact CD1-CB 4.28Å; I264-K297 HydrophobicContact CG1-CB 4.24Å; I264-K297 HydrophobicContact CG1-CD 4.44Å; I264-K297 HydrophobicContact CG2-CD 4.28Å; I293-K297 VanDerWaalsContact O-CG 3.31Å; I293-K297 WeakPolarHBondContact O-CG 3.46Å; I293-K297 PolarHBondContact O-N 2.89Å; C294-K297 PolarHBondContact O-N 3.37Å; L295-K297 PolarHBondContact O-N 3Å; K297-A301 WeakPolarHBondContact O-CB 3.35Å; K297-A301 PolarHBondContact O-N 3.37Å; K297-A301 VanDerWaalsContact O-N 3.13Å
298L97.9Very high97.3Very high2 Ų220.4 Ų20.41%0.0113%0.126CC..Hα-helixtrans-67.5-41.3-178.4-175.963.1000111.5F120 F121 F262 I264 L290 C294 L295 H296 A301 G302 F304F120-L298 HydrophobicContact CD1-CD2 4.46Å; F120-L298 HydrophobicContact CE1-CD2 4.1Å; F121-L298 HydrophobicContact CD1-CD1 4.1Å; F121-L298 HydrophobicContact CD1-CD2 4.25Å; F121-L298 HydrophobicContact CE1-CD1 4.19Å; F121-L298 HydrophobicContact CE1-CD2 4.26Å; F262-L298 HydrophobicContact CD1-CD1 3.88Å; F262-L298 HydrophobicContact CD2-CD1 3.88Å; F262-L298 HydrophobicContact CE1-CD1 3.85Å; F262-L298 HydrophobicContact CE2-CD1 3.88Å; F262-L298 HydrophobicContact CG-CD1 3.88Å; F262-L298 HydrophobicContact CZ-CD1 3.87Å; I264-L298 HydrophobicContact CD1-CB 4.07Å; I264-L298 HydrophobicContact CD1-CD1 4.41Å; L290-L298 HydrophobicContact CD1-CB 3.94Å; L290-L298 HydrophobicContact CD1-CD2 3.49Å; L290-L298 VanDerWaalsContact CD1-CD2 3.49Å; L290-L298 HydrophobicContact CD1-CG 4.34Å; C294-L298 WeakPolarHBondContact O-CB 3.31Å; C294-L298 PolarHBondContact O-N 3.39Å; L295-L298 PolarHBondContact O-N 3.1Å; H296-L298 PolarHBondContact O-N 2.88Å; L298-A301 PolarHBondContact O-N 2.72Å; L298-G302 PolarHBondContact O-N 2.82Å; L298-F304 HydrophobicContact CB-CZ 4.48Å; L298-F304 HydrophobicContact CD2-CE1 4.27Å; L298-F304 HydrophobicContact CD2-CZ 4.14Å; L298-F304 HydrophobicContact CG-CE1 3.87Å; L298-F304 HydrophobicContact CG-CZ 3.99Å
299Q97.6Very high97.3Very high32 Ų3220.3 Ų20.315%0.1513%0.125CC..Hα-helixtrans-65.3-42180-169.9-76.1-31.100111.4Y29 L295 H296 A301 G302 G303 F304 I306Y29-Q299 HydrophobicContact CE1-CG 4.01Å; Y29-Q299 VanDerWaalsContact CE1-OE1 3.27Å; Y29-Q299 VanDerWaalsContact CZ-OE1 3.23Å; Y29-Q299 PolarHBondContact OH-OE1 2.89Å; L295-Q299 VanDerWaalsContact O-CB 3.22Å; L295-Q299 WeakPolarHBondContact O-CB 3.49Å; L295-Q299 PolarHBondContact O-N 2.81Å; H296-Q299 PolarHBondContact O-N 2.68Å; Q299-A301 VanDerWaalsContact C-N 3.26Å; Q299-A301 PolarHBondContact O-N 3.33Å; Q299-G302 PolarHBondContact O-N 2.91Å; Q299-G303 WeakPolarHBondContact O-CA 3.25Å; Q299-G303 PolarHBondContact O-N 2.94Å; Q299-F304 HydrophobicContact CB-CE2 4.08Å; Q299-F304 HydrophobicContact CB-CZ 3.94Å; Q299-F304 HydrophobicContact CG-CD2 4.3Å; Q299-F304 HydrophobicContact CG-CE2 4.06Å; Q299-F304 HydrophobicContact CG-CZ 4.36Å; Q299-F304 VanDerWaalsContact CG-O 3.28Å; Q299-F304 WeakPolarHBondContact CG-O 3.28Å; Q299-F304 PolarHBondContact NE2-O 3.45Å; Q299-I306 HydrophobicContact CG-CG1 4.15Å
300V96.4Very high97.4Very high32 Ų3220 Ų2019%0.19412%0.124CC..Hα-helixtrans-66-31.3175.2168.30000111.7L25 F72 Y76 H296L25-V300 HydrophobicContact CD1-CG1 4.35Å; F72-V300 HydrophobicContact CE2-CB 4Å; F72-V300 HydrophobicContact CE2-CG1 4.2Å; F72-V300 HydrophobicContact CE2-CG2 3.83Å; F72-V300 HydrophobicContact CZ-CB 4.21Å; F72-V300 HydrophobicContact CZ-CG1 4.08Å; F72-V300 HydrophobicContact CZ-CG2 3.78Å; Y76-V300 HydrophobicContact CD2-CG1 4.01Å; Y76-V300 HydrophobicContact CE2-CG1 3.96Å; H296-V300 VanDerWaalsContact CE1-CG2 3.43Å; H296-V300 WeakPolarHBondContact CE1-CG2 3.37Å; H296-V300 WeakPolarHBondContact O-CB 3.24Å; H296-V300 WeakPolarHBondContact O-CG2 3.4Å; H296-V300 PolarHBondContact O-N 3.43Å
301A95.3Very high97.4Very high5 Ų523.6 Ų23.64%0.04114%0.139CC..Hα-helixtrans-78.2-37.3175.800000113F75 T83 P84 F262 K297 L298 Q299F75-A301 HydrophobicContact CZ-CB 4.31Å; T83-A301 WeakPolarHBondContact CG2-O 3.33Å; P84-A301 WeakPolarHBondContact CD-O 3.09Å; F262-A301 HydrophobicContact CD1-CB 3.76Å; F262-A301 HydrophobicContact CE1-CB 4.44Å; K297-A301 WeakPolarHBondContact O-CB 3.35Å; K297-A301 PolarHBondContact O-N 3.37Å; K297-A301 VanDerWaalsContact O-N 3.13Å; L298-A301 PolarHBondContact O-N 2.72Å; Q299-A301 VanDerWaalsContact C-N 3.26Å; Q299-A301 PolarHBondContact O-N 3.33Å
302G93.9Very high97.3Very high23 Ų2324.5 Ų24.524%0.23715%0.147CC..Hα-helixtrans-96.5-19-174.700000115.4L298 Q299 F304L298-G302 PolarHBondContact O-N 2.82Å; Q299-G302 PolarHBondContact O-N 2.91Å; G302-F304 PolarHBondContact O-N 3.35Å
303G95Very high97.3Very high63 Ų6324.4 Ų24.465%0.64915%0.146SC*.  trans68.114.2178.900000115.7Q299Q299-G303 WeakPolarHBondContact O-CA 3.25Å; Q299-G303 PolarHBondContact O-N 2.94Å
304F95.6Very high97.3Very high14 Ų1425.2 Ų25.26%0.06115%0.151CC..  trans-80.7162.6179.758.8-95.5000112.7C122 L295 L298 Q299 G302 R309C122-F304 HydrophobicContact CB-CB 3.98Å; C122-F304 HydrophobicContact CB-CD1 4.4Å; C122-F304 HydrophobicContact CB-CG 4.05Å; C122-F304 WeakPolarHBondContact O-CD1 3.49Å; L295-F304 HydrophobicContact CD1-CE2 4.38Å; L295-F304 HydrophobicContact CD1-CZ 4.48Å; L298-F304 HydrophobicContact CB-CZ 4.48Å; L298-F304 HydrophobicContact CD2-CE1 4.27Å; L298-F304 HydrophobicContact CD2-CZ 4.14Å; L298-F304 HydrophobicContact CG-CE1 3.87Å; L298-F304 HydrophobicContact CG-CZ 3.99Å; Q299-F304 HydrophobicContact CB-CE2 4.08Å; Q299-F304 HydrophobicContact CB-CZ 3.94Å; Q299-F304 HydrophobicContact CG-CD2 4.3Å; Q299-F304 HydrophobicContact CG-CE2 4.06Å; Q299-F304 HydrophobicContact CG-CZ 4.36Å; Q299-F304 VanDerWaalsContact CG-O 3.28Å; Q299-F304 WeakPolarHBondContact CG-O 3.28Å; Q299-F304 PolarHBondContact NE2-O 3.45Å; G302-F304 PolarHBondContact O-N 3.35Å; F304-R309 HydrophobicContact CD2-CB 3.91Å; F304-R309 HydrophobicContact CE2-CB 4.1Å; F304-R309 HydrophobicContact CE2-CG 4.34Å
305K96.7Very high97.2Very high138 Ų13832.2 Ų32.260%0.618%0.177SC*.  trans-84.2133.9167.6-61.3-175.7-175.11700110A307 D308 R309K305-A307 VanDerWaalsContact C-N 3.3Å; K305-A307 PolarHBondContact O-N 3.35Å; K305-D308 HydrophobicContact CB-CB 4.26Å; K305-D308 WeakPolarHBondContact CD-OD2 3.49Å; K305-D308 PolarHBondContact O-N 2.84Å; K305-R309 PolarHBondContact O-N 3.21Å
306I97.7Very high97.1Very high0 Ų032.9 Ų32.90%018%0.179CC..Hα-helixtrans-61.1-41.5-175.3-63.5176.1000111.1Y29 E33 L36 L37 L295 Q299 D308 R309 Y310 L360Y29-I306 HydrophobicContact CE1-CD1 4.06Å; E33-I306 HydrophobicContact CB-CD1 4.34Å; E33-I306 HydrophobicContact CG-CB 4.41Å; E33-I306 HydrophobicContact CG-CD1 4.18Å; E33-I306 PolarHBondContact OE1-N 3.13Å; L36-I306 HydrophobicContact CD2-CG2 3.8Å; L37-I306 HydrophobicContact CD1-CD1 4.4Å; L37-I306 HydrophobicContact CD2-CD1 4.35Å; L37-I306 HydrophobicContact CG-CD1 4.44Å; L295-I306 HydrophobicContact CD2-CD1 4.03Å; L295-I306 HydrophobicContact CD2-CG1 4.48Å; L295-I306 HydrophobicContact CD2-CG2 4.05Å; L295-I306 HydrophobicContact CG-CD1 4.27Å; Q299-I306 HydrophobicContact CG-CG1 4.15Å; I306-D308 PolarHBondContact O-N 2.88Å; I306-R309 PolarHBondContact O-N 3.25Å; I306-Y310 HydrophobicContact CG2-CD2 3.84Å; I306-Y310 HydrophobicContact CG2-CE2 3.44Å; I306-Y310 VanDerWaalsContact CG2-CE2 3.44Å; I306-Y310 PolarHBondContact O-N 3.47Å; I306-L360 HydrophobicContact CG2-CD1 4.07Å
307A97.3Very high97Very high23 Ų2332.9 Ų32.919%0.1918%0.179CC..Hα-helixtrans-60.9-41.9178.700000112.8K305 Y310 K311 L357 L360K305-A307 VanDerWaalsContact C-N 3.3Å; K305-A307 PolarHBondContact O-N 3.35Å; A307-Y310 PolarHBondContact O-N 3.5Å; A307-K311 WeakPolarHBondContact O-CB 3.29Å; A307-K311 VanDerWaalsContact O-CG 3.3Å; A307-K311 WeakPolarHBondContact O-CG 3.29Å; A307-K311 PolarHBondContact O-N 3.08Å; A307-L357 HydrophobicContact CB-CD2 4.48Å; A307-L360 HydrophobicContact CB-CD1 4.01Å
308D97.4Very high96.7Very high78 Ų7836.2 Ų36.242%0.41720%0.195SC..Hα-helixtrans-66.2-41.7-178.4-65.9-16.1000111K305 I306 K311 A312K305-D308 HydrophobicContact CB-CB 4.26Å; K305-D308 WeakPolarHBondContact CD-OD2 3.49Å; K305-D308 PolarHBondContact O-N 2.84Å; I306-D308 PolarHBondContact O-N 2.88Å; D308-K311 PolarHBondContact O-N 2.59Å; D308-A312 WeakPolarHBondContact O-CB 3.34Å; D308-A312 PolarHBondContact O-N 3.24Å
309R98Very high96.2Very high0 Ų040.2 Ų40.20%022%0.217CC..Hα-helixtrans-59.8-48.8173.3-179.2-177166.4-77-6.4111.5F120 C122 D289 F304 K305 I306 K311 A312 L313F120-R309 VanDerWaalsContact O-CD 3.28Å; F120-R309 WeakPolarHBondContact O-CD 3.49Å; F120-R309 PolarHBondContact O-NE 3.48Å; C122-R309 HydrophobicContact CB-CB 3.84Å; C122-R309 HydrophobicContact CB-CG 4.03Å; D289-R309 IonicContact OD1-CZ 2.89Å; D289-R309 IonicContact OD1-NH1 3.29Å; D289-R309 PolarHBondContact OD1-NH1 2.88Å; D289-R309 IonicContact OD1-NH2 3.84Å; D289-R309 PolarHBondContact OD1-NH2 2.78Å; F304-R309 HydrophobicContact CD2-CB 3.91Å; F304-R309 HydrophobicContact CE2-CB 4.1Å; F304-R309 HydrophobicContact CE2-CG 4.34Å; K305-R309 PolarHBondContact O-N 3.21Å; I306-R309 PolarHBondContact O-N 3.25Å; R309-K311 PolarHBondContact O-N 3.43Å; R309-A312 PolarHBondContact O-N 2.84Å; R309-L313 HydrophobicContact CG-CD1 4.23Å; R309-L313 WeakPolarHBondContact O-CG 3.49Å; R309-L313 PolarHBondContact O-N 3.4Å
310Y98.4Very high94.7Very high1 Ų142.3 Ų42.30%0.00423%0.229CC..Hα-helixtrans-65.5-38178.9-69.4-23.3000113.1L36 L295 I306 A307 A312 L313 L314 W352 L353 C356 L360L36-Y310 HydrophobicContact CD2-CE2 3.67Å; L295-Y310 VanDerWaalsContact CD2-OH 3.23Å; L295-Y310 WeakPolarHBondContact CD2-OH 3.42Å; I306-Y310 HydrophobicContact CG2-CD2 3.84Å; I306-Y310 HydrophobicContact CG2-CE2 3.44Å; I306-Y310 VanDerWaalsContact CG2-CE2 3.44Å; I306-Y310 PolarHBondContact O-N 3.47Å; A307-Y310 PolarHBondContact O-N 3.5Å; Y310-A312 VanDerWaalsContact C-N 3.34Å; Y310-L313 HydrophobicContact CD1-CD1 4.43Å; Y310-L313 PolarHBondContact O-N 3.47Å; Y310-L314 WeakPolarHBondContact O-CB 3.31Å; Y310-L314 PolarHBondContact O-N 3.48Å; Y310-W352 HydrophobicContact CE1-CH2 4.15Å; Y310-W352 HydrophobicContact CE1-CZ3 4Å; Y310-W352 AromaticContact CZ-CH2 3.94Å; Y310-W352 WeakPolarHBondContact OH-CH2 3.35Å; Y310-L353 HydrophobicContact CD1-CD2 3.38Å; Y310-L353 HydrophobicContact CE1-CD2 4Å; Y310-L353 HydrophobicContact CG-CD2 3.77Å; Y310-C356 HydrophobicContact CD2-CB 3.83Å; Y310-C356 HydrophobicContact CE2-CB 3.61Å; Y310-L360 HydrophobicContact CD2-CD1 3.84Å; Y310-L360 HydrophobicContact CE2-CD1 4.19Å
311K98Very high92.7Very high79 Ų7946.7 Ų46.734%0.34325%0.247SC..Hα-helixtrans-63.7-37.9173-73.2173.7-175.6-174.50111.8A307 D308 R309 R315 L357 E361A307-K311 WeakPolarHBondContact O-CB 3.29Å; A307-K311 VanDerWaalsContact O-CG 3.3Å; A307-K311 WeakPolarHBondContact O-CG 3.29Å; A307-K311 PolarHBondContact O-N 3.08Å; D308-K311 PolarHBondContact O-N 2.59Å; R309-K311 PolarHBondContact O-N 3.43Å; K311-R315 WeakPolarHBondContact O-CB 3.06Å; K311-R315 VanDerWaalsContact O-CG 3.28Å; K311-R315 WeakPolarHBondContact O-CG 3.19Å; K311-R315 PolarHBondContact O-N 2.82Å; K311-R315 PolarHBondContact O-NE 2.86Å; K311-L357 HydrophobicContact CD-CD2 4.46Å; K311-L357 HydrophobicContact CG-CD1 4.19Å; K311-L357 HydrophobicContact CG-CD2 3.79Å; K311-E361 WeakPolarHBondContact CE-OE1 3.29Å; K311-E361 IonicContact NZ-OE1 3.84Å; K311-E361 PolarHBondContact NZ-OE1 3.11Å
312A97.9Very high90.2Very high19 Ų1950.9 Ų50.916%0.15728%0.276CS..Hα-helixtrans-66.6-44.5175.500000111.9A119 D308 R309 Y310 R315 W316A119-A312 HydrophobicContact CB-CB 3.97Å; D308-A312 WeakPolarHBondContact O-CB 3.34Å; D308-A312 PolarHBondContact O-N 3.24Å; R309-A312 PolarHBondContact O-N 2.84Å; Y310-A312 VanDerWaalsContact C-N 3.34Å; A312-R315 PolarHBondContact O-N 3.16Å; A312-W316 WeakPolarHBondContact O-CB 3.03Å; A312-W316 PolarHBondContact O-N 3.37Å
313L98.2Very high87.7Confident0 Ų058.4 Ų58.40%031%0.305CS..Hα-helixtrans-63.7-43.5176.8-73.4169000112.3Y116 A119 F120 R309 Y310 W316 M317 L353Y116-L313 HydrophobicContact CD2-CD2 4.08Å; Y116-L313 HydrophobicContact CE2-CD2 3.76Å; A119-L313 HydrophobicContact CB-CD2 3.99Å; A119-L313 HydrophobicContact CB-CG 4.37Å; F120-L313 HydrophobicContact CB-CD2 4.02Å; F120-L313 HydrophobicContact CD2-CD1 4.14Å; F120-L313 HydrophobicContact CD2-CD2 4Å; F120-L313 HydrophobicContact CG-CD2 4.47Å; R309-L313 HydrophobicContact CG-CD1 4.23Å; R309-L313 WeakPolarHBondContact O-CG 3.49Å; R309-L313 PolarHBondContact O-N 3.4Å; Y310-L313 HydrophobicContact CD1-CD1 4.43Å; Y310-L313 PolarHBondContact O-N 3.47Å; L313-W316 PolarHBondContact O-N 3.24Å; L313-M317 WeakPolarHBondContact O-CG 3.17Å; L313-M317 PolarHBondContact O-N 3.47Å; L313-L353 HydrophobicContact CB-CD1 3.81Å; L313-L353 HydrophobicContact CB-CD2 4.45Å; L313-L353 HydrophobicContact CD1-CD2 4.44Å
314L97.6Very high85.3Confident19 Ų1962.8 Ų62.810%0.09931%0.313CS..Hα-helixtrans-63.8-46.8178.9-173.863.4000111.1Y310 W316 M317 E318 R350 L353 R354 L357Y310-L314 WeakPolarHBondContact O-CB 3.31Å; Y310-L314 PolarHBondContact O-N 3.48Å; L314-W316 PolarHBondContact O-N 3.07Å; L314-M317 PolarHBondContact O-N 3.07Å; L314-E318 HydrophobicContact CD1-CG 4.26Å; L314-E318 VanDerWaalsContact CD1-OE1 3.28Å; L314-E318 WeakPolarHBondContact CD1-OE1 3.35Å; L314-E318 HydrophobicContact CG-CG 4.42Å; L314-E318 WeakPolarHBondContact O-CB 3.17Å; L314-E318 WeakPolarHBondContact O-CG 3.5Å; L314-E318 PolarHBondContact O-N 3.26Å; L314-R350 HydrophobicContact CD1-CB 4.16Å; L314-R350 HydrophobicContact CD1-CG 4.31Å; L314-L353 HydrophobicContact CB-CD1 4.39Å; L314-L353 HydrophobicContact CD1-CB 4.35Å; L314-R354 HydrophobicContact CD1-CG 4.1Å; L314-R354 HydrophobicContact CD2-CG 3.72Å; L314-L357 HydrophobicContact CD2-CD1 3.96Å
315R96.9Very high82.6Confident147 Ų14766.5 Ų66.556%0.55534%0.341SS*.Hα-helixtrans-55.7-49.5172.9-77.3-178-68.8167.7-0.5111.2K311 A312 M317 E318 D319K311-R315 WeakPolarHBondContact O-CB 3.06Å; K311-R315 VanDerWaalsContact O-CG 3.28Å; K311-R315 WeakPolarHBondContact O-CG 3.19Å; K311-R315 PolarHBondContact O-N 2.82Å; K311-R315 PolarHBondContact O-NE 2.86Å; A312-R315 PolarHBondContact O-N 3.16Å; R315-M317 PolarHBondContact O-N 2.63Å; R315-M317 VanDerWaalsContact O-N 3.12Å; R315-E318 CarbonylContact O-C 3.54Å; R315-E318 PolarHBondContact O-N 3.42Å; R315-D319 VanDerWaalsContact O-CB 3.3Å; R315-D319 WeakPolarHBondContact O-CB 3.44Å; R315-D319 PolarHBondContact O-N 2.59Å
316W96.6Very high79.8Confident13 Ų1369.8 Ų69.85%0.04936%0.358CS..Hα-helixtrans-57-33.2176.9-179.491.7000112.9W112 Y116 A119 L247 A312 L313 L314 K341 F346W112-W316 HydrophobicContact CB-CZ2 4.11Å; W112-W316 WeakPolarHBondContact O-CZ2 3.35Å; W112-W316 PolarHBondContact O-NE1 2.84Å; Y116-W316 HydrophobicContact CD2-CD2 4.12Å; Y116-W316 AromaticContact CD2-CE3 3.81Å; Y116-W316 HydrophobicContact CD2-CE3 3.81Å; Y116-W316 HydrophobicContact CD2-CH2 4.15Å; Y116-W316 HydrophobicContact CD2-CZ2 4.43Å; Y116-W316 AromaticContact CD2-CZ3 3.85Å; Y116-W316 HydrophobicContact CD2-CZ3 3.85Å; Y116-W316 HydrophobicContact CG-CH2 4.41Å; Y116-W316 HydrophobicContact CG-CZ2 4.36Å; A119-W316 HydrophobicContact CB-CB 4.49Å; L247-W316 HydrophobicContact CD1-CH2 4.48Å; L247-W316 HydrophobicContact CD2-CH2 4.01Å; L247-W316 HydrophobicContact CD2-CZ2 4.41Å; L247-W316 HydrophobicContact CG-CH2 4.21Å; A312-W316 WeakPolarHBondContact O-CB 3.03Å; A312-W316 PolarHBondContact O-N 3.37Å; L313-W316 PolarHBondContact O-N 3.24Å; L314-W316 PolarHBondContact O-N 3.07Å; W316-K341 HydrophobicContact CH2-CD 4.39Å; W316-K341 HydrophobicContact CZ2-CD 3.91Å; W316-K341 WeakPolarHBondContact O-CE 3.33Å; W316-K341 PolarHBondContact O-NZ 3.09Å; W316-F346 HydrophobicContact CH2-CE1 4.03Å; W316-F346 AromaticContact CH2-CZ 3.84Å; W316-F346 HydrophobicContact CH2-CZ 3.84Å; W316-F346 HydrophobicContact CZ3-CD1 4.07Å; W316-F346 AromaticContact CZ3-CE1 3.57Å; W316-F346 HydrophobicContact CZ3-CE1 3.57Å; W316-F346 AromaticContact CZ3-CZ 3.84Å; W316-F346 HydrophobicContact CZ3-CZ 3.84Å
317M95.8Very high77Confident0 Ų073.9 Ų73.90%039%0.392CS..Hα-helixtrans-79.5-25.2177.2-65.2177.6-163.600114L288 L313 L314 R315 T343 F346 R350 L353L288-M317 HydrophobicContact CD2-CE 3.62Å; L313-M317 WeakPolarHBondContact O-CG 3.17Å; L313-M317 PolarHBondContact O-N 3.47Å; L314-M317 PolarHBondContact O-N 3.07Å; R315-M317 PolarHBondContact O-N 2.63Å; R315-M317 VanDerWaalsContact O-N 3.12Å; M317-T343 PolarHBondContact O-OG1 3.37Å; M317-F346 HydrophobicContact CE-CD1 3.97Å; M317-F346 HydrophobicContact CG-CB 4.34Å; M317-F346 HydrophobicContact CG-CD1 4.08Å; M317-F346 HydrophobicContact CG-CG 4.48Å; M317-F346 HydrophobicContact SD-CB 4.05Å; M317-F346 HydrophobicContact SD-CD1 4.03Å; M317-R350 HydrophobicContact CB-CG 3.7Å; M317-R350 HydrophobicContact CG-CG 4.26Å; M317-R350 HydrophobicContact SD-CG 3.59Å; M317-R350 VanDerWaalsContact SD-CG 3.59Å; M317-L353 HydrophobicContact CE-CD1 3.66Å; M317-L353 HydrophobicContact SD-CD1 3.93Å
318E93.1Very high74.3Confident72 Ų7280.7 Ų80.734%0.33642%0.42SS..Hα-helixtrans-99.9-18.8-175.3-68.6177.5169.400113.5L314 R315 D320 R354L314-E318 HydrophobicContact CD1-CG 4.26Å; L314-E318 VanDerWaalsContact CD1-OE1 3.28Å; L314-E318 WeakPolarHBondContact CD1-OE1 3.35Å; L314-E318 HydrophobicContact CG-CG 4.42Å; L314-E318 WeakPolarHBondContact O-CB 3.17Å; L314-E318 WeakPolarHBondContact O-CG 3.5Å; L314-E318 PolarHBondContact O-N 3.26Å; R315-E318 CarbonylContact O-C 3.54Å; R315-E318 PolarHBondContact O-N 3.42Å; E318-D320 VanDerWaalsContact C-N 3.28Å; E318-D320 PolarHBondContact O-N 3.22Å; E318-R354 IonicContact OE1-CZ 3.47Å; E318-R354 VanDerWaalsContact OE1-CZ 3.31Å; E318-R354 IonicContact OE1-NE 2.72Å; E318-R354 PolarHBondContact OE1-NE 3.17Å; E318-R354 IonicContact OE1-NH2 3.67Å; E318-R354 PolarHBondContact OE1-NH2 2.86Å
319D86.3Confident71.4Confident87 Ų8780.6 Ų80.647%0.46544%0.438SS..  trans-6790.3175.9-71.5-16.3000108.5R315 K341R315-D319 VanDerWaalsContact O-CB 3.3Å; R315-D319 WeakPolarHBondContact O-CB 3.44Å; R315-D319 PolarHBondContact O-N 2.59Å; D319-K341 VanDerWaalsContact O-CE 3.28Å; D319-K341 WeakPolarHBondContact O-CE 3.34Å; D319-K341 PolarHBondContact O-NZ 3.34Å
320D65.6Low68.6Low75 Ų7585.2 Ų85.240%0.40148%0.475SS..  trans-70.6131.9150.9-63.8-16.2000105.4E318 S322 H340E318-D320 VanDerWaalsContact C-N 3.28Å; E318-D320 PolarHBondContact O-N 3.22Å; D320-S322 PolarHBondContact O-N 3.01Å; D320-S322 PolarHBondContact O-OG 3.11Å; D320-S322 VanDerWaalsContact O-OG 3.08Å; D320-H340 IonicContact OD1-CE1 2.72Å; D320-H340 PolarHBondContact OD1-CE1 2.94Å; D320-H340 IonicContact OD1-ND1 3.39Å; D320-H340 IonicContact OD1-NE2 2.7Å; D320-H340 PolarHBondContact OD1-NE2 3.12Å; D320-H340 VanDerWaalsContact OD1-NE2 3.17Å; D320-H340 IonicContact OD2-NE2 3.69Å
321E56Low65.7Low124 Ų12489.8 Ų89.858%0.57951%0.513SS*.SBendtrans-60.371.6178-71.4-176.1170.500111.5R108R108-E321 IonicContact NH1-OE1 3.44Å
322S42.8Very low62.8Low94 Ų9490.3 Ų90.366%0.65753%0.533SS*.  trans-113.75.7-17857.80000111.7D320D320-S322 PolarHBondContact O-N 3.01Å; D320-S322 PolarHBondContact O-OG 3.11Å; D320-S322 VanDerWaalsContact O-OG 3.08Å
323Q41.8Very low60.1Low180 Ų18098.4 Ų98.484%0.84157%0.567SS**SBendtrans-111.425.7179.5-66.6-151.5-5.400115.1
324L44.2Very low57.2Low156 Ų156107.3 Ų107.382%0.81761%0.608SS**SBendtrans-13468.4167.2-71.8171.8000111
325S38.8Very low54.4Low92 Ų92112 Ų11264%0.64364%0.643SS**SBendtrans-1425.5156.869.70000114.7A327S325-A327 VanDerWaalsContact C-N 3.26Å; S325-A327 PolarHBondContact O-N 3.36Å
326E37.7Very low52Low207 Ų207107.7 Ų107.797%0.96764%0.638SS**SBendtrans-82.1-2.7166.8-71.9-167.7163.500113.3
327A39.2Very low49.7Very low86 Ų86111.3 Ų111.371%0.71166%0.662SS**SBendtrans-112.2-2.1175.300000114.8S325S325-A327 VanDerWaalsContact C-N 3.26Å; S325-A327 PolarHBondContact O-N 3.36Å
328E40.6Very low47.8Very low165 Ų165119.2 Ų119.277%0.77170%0.698SS**  trans-103.541.8174-69.7-169.7160.800111.8A330E328-A330 VanDerWaalsContact C-N 3.31Å; E328-A330 PolarHBondContact O-N 2.96Å; E328-A330 VanDerWaalsContact O-N 3.12Å
329G36.5Very low46.6Very low77 Ų77118.2 Ų118.279%0.79469%0.693SS**SBendtrans-73.589.915300000109.1
330A39.5Very low46.5Very low96 Ų96119.3 Ų119.379%0.79370%0.695SS**SBendtrans96.983.7169.700000117.7E328E328-A330 VanDerWaalsContact C-N 3.31Å; E328-A330 PolarHBondContact O-N 2.96Å; E328-A330 VanDerWaalsContact O-N 3.12Å
331A36.7Very low47.7Very low97 Ų97116.5 Ų116.580%0.80268%0.679SS**  -177.8111.6123.400000112.8
332A37.3Very low49.4Very low90 Ų90111.4 Ų111.474%0.74466%0.657SS**  trans35.3117.3144.400000122.1
333H41.3Very low51.9Low189 Ų189107.2 Ų107.288%0.87563%0.627SS**  trans43.977.7133.3-78.4-66.9000118.8
334H36.7Very low54.4Low187 Ų187104.3 Ų104.387%0.86661%0.614SS**  trans-140.7127.3137.1-82.4-71000108.5A336H334-A336 PolarHBondContact O-N 3.23Å
335S38.9Very low56.9Low119 Ų11998.6 Ų98.683%0.83259%0.589SS**  trans-66.179.2170.3170.60000108.6V337S335-V337 PolarHBondContact O-N 3.46Å; S335-V337 VanDerWaalsContact O-N 3.12Å
336A46.5Very low59.7Low55 Ų5594.2 Ų94.246%0.45556%0.558SS.*  trans-63.2113.4171.900000107.2H334 H338H334-A336 PolarHBondContact O-N 3.23Å; A336-H338 PolarHBondContact O-CD2 3.39Å; A336-H338 PolarHBondContact O-N 3.26Å
337V49Very low62.5Low90 Ų9088 Ų8855%0.54553%0.532SS..  trans-65.7105170.6-176.10000105.9S335 F339S335-V337 PolarHBondContact O-N 3.46Å; S335-V337 VanDerWaalsContact O-N 3.12Å; V337-F339 HydrophobicContact CB-CE1 4.38Å; V337-F339 HydrophobicContact CB-CE2 3.9Å; V337-F339 HydrophobicContact CB-CZ 3.67Å; V337-F339 HydrophobicContact CG1-CD1 4.39Å; V337-F339 HydrophobicContact CG1-CE1 3.5Å; V337-F339 VanDerWaalsContact CG1-CE1 3.5Å; V337-F339 HydrophobicContact CG1-CE2 3.92Å; V337-F339 HydrophobicContact CG1-CZ 3.24Å; V337-F339 VanDerWaalsContact O-CD2 3.23Å; V337-F339 WeakPolarHBondContact O-CD2 3.37Å; V337-F339 VanDerWaalsContact O-CE2 3.27Å; V337-F339 WeakPolarHBondContact O-CE2 3.43Å; V337-F339 PolarHBondContact O-N 2.94Å
338H54.4Low65.2Low165 Ų16591.6 Ų91.676%0.76453%0.534SS*.  trans-69.7118.3179.3-67.8-76.5000109.2A336A336-H338 PolarHBondContact O-CD2 3.39Å; A336-H338 PolarHBondContact O-N 3.26Å
339F68.9Low67.9Low52 Ų5284.5 Ų84.523%0.22850%0.503CS..  trans-100.3106.2175.4-65.8-63.8000109.5L104 Q105 W112 V337L104-F339 HydrophobicContact CB-CE2 4.34Å; Q105-F339 HydrophobicContact CB-CD2 4.45Å; Q105-F339 HydrophobicContact CB-CE2 4.43Å; Q105-F339 HydrophobicContact CG-CD1 3.53Å; Q105-F339 HydrophobicContact CG-CD2 3.51Å; Q105-F339 HydrophobicContact CG-CE1 3.35Å; Q105-F339 HydrophobicContact CG-CE2 3.27Å; Q105-F339 HydrophobicContact CG-CG 3.64Å; Q105-F339 HydrophobicContact CG-CZ 3.18Å; W112-F339 HydrophobicContact CH2-CB 4.47Å; V337-F339 HydrophobicContact CB-CE1 4.38Å; V337-F339 HydrophobicContact CB-CE2 3.9Å; V337-F339 HydrophobicContact CB-CZ 3.67Å; V337-F339 HydrophobicContact CG1-CD1 4.39Å; V337-F339 HydrophobicContact CG1-CE1 3.5Å; V337-F339 VanDerWaalsContact CG1-CE1 3.5Å; V337-F339 HydrophobicContact CG1-CE2 3.92Å; V337-F339 HydrophobicContact CG1-CZ 3.24Å; V337-F339 VanDerWaalsContact O-CD2 3.23Å; V337-F339 WeakPolarHBondContact O-CD2 3.37Å; V337-F339 VanDerWaalsContact O-CE2 3.27Å; V337-F339 WeakPolarHBondContact O-CE2 3.43Å; V337-F339 PolarHBondContact O-N 2.94Å
340H83.2Confident70.7Confident110 Ų11083.6 Ų83.651%0.50948%0.475SS..  trans-67.5133.1172.8-170.1-42.6000109.8D320 P342D320-H340 IonicContact OD1-CE1 2.72Å; D320-H340 PolarHBondContact OD1-CE1 2.94Å; D320-H340 IonicContact OD1-ND1 3.39Å; D320-H340 IonicContact OD1-NE2 2.7Å; D320-H340 PolarHBondContact OD1-NE2 3.12Å; D320-H340 VanDerWaalsContact OD1-NE2 3.17Å; D320-H340 IonicContact OD2-NE2 3.69Å; H340-P342 VanDerWaalsContact O-CD 3.29Å; H340-P342 WeakPolarHBondContact O-CD 3.09Å
341K91.3Very high73.5Confident15 Ų1583.2 Ų83.27%0.06546%0.459CS..  trans-62.3112.9170.5-177.917658.7-150.50109.7W112 L247 W316 D319 T343W112-K341 HydrophobicContact CB-CD 4.37Å; W112-K341 HydrophobicContact CD2-CB 4.02Å; W112-K341 HydrophobicContact CD2-CD 4.24Å; W112-K341 HydrophobicContact CD2-CG 3.74Å; W112-K341 HydrophobicContact CE3-CB 4.49Å; W112-K341 HydrophobicContact CE3-CG 4.15Å; W112-K341 HydrophobicContact CG-CD 3.89Å; W112-K341 HydrophobicContact CG-CG 3.94Å; W112-K341 HydrophobicContact CH2-CB 4.32Å; W112-K341 VanDerWaalsContact CZ2-CA 3.49Å; W112-K341 HydrophobicContact CZ2-CB 3.81Å; W112-K341 HydrophobicContact CZ2-CG 4.45Å; L247-K341 HydrophobicContact CD2-CG 3.95Å; W316-K341 HydrophobicContact CH2-CD 4.39Å; W316-K341 HydrophobicContact CZ2-CD 3.91Å; W316-K341 WeakPolarHBondContact O-CE 3.33Å; W316-K341 PolarHBondContact O-NZ 3.09Å; D319-K341 VanDerWaalsContact O-CE 3.28Å; D319-K341 WeakPolarHBondContact O-CE 3.34Å; D319-K341 PolarHBondContact O-NZ 3.34Å; K341-T343 HydrophobicContact CD-CG2 4.15Å; K341-T343 HydrophobicContact CG-CG2 3.82Å; K341-T343 PolarHBondContact O-N 2.87Å
342P91.9Very high76.3Confident18 Ų1880.9 Ų80.912%0.11743%0.43CS..  trans-78.6102.1-171.132.5-35.2000109.4W112 I242 S244 L247 H340W112-P342 VanDerWaalsContact CZ3-CD 3.48Å; W112-P342 HydrophobicContact CZ3-CG 4.49Å; I242-P342 HydrophobicContact CG2-CG 4.27Å; S244-P342 WeakPolarHBondContact CA-O 3.09Å; S244-P342 VanDerWaalsContact CB-C 3.48Å; S244-P342 WeakPolarHBondContact CB-O 3.05Å; L247-P342 HydrophobicContact CD2-CG 4.35Å; H340-P342 VanDerWaalsContact O-CD 3.29Å; H340-P342 WeakPolarHBondContact O-CD 3.09Å
343T94.5Very high79.2Confident6 Ų676.6 Ų76.64%0.03739%0.394CS..  trans-112.513.8-175.461.50000114.1M317 K341 A345 F346M317-T343 PolarHBondContact O-OG1 3.37Å; K341-T343 HydrophobicContact CD-CG2 4.15Å; K341-T343 HydrophobicContact CG-CG2 3.82Å; K341-T343 PolarHBondContact O-N 2.87Å; T343-A345 VanDerWaalsContact C-N 3.29Å; T343-A345 PolarHBondContact O-N 3.18Å; T343-F346 HydrophobicContact CG2-CD2 4.45Å; T343-F346 WeakPolarHBondContact O-CB 3.28Å; T343-F346 PolarHBondContact O-N 3.19Å
344E95.5Very high81.9Confident119 Ų11973.2 Ų73.256%0.55637%0.374SS*.G310 helixtrans-59.6-40.3-177-55.978.4-167.800112.2S244 F346 N347S244-E344 WeakPolarHBondContact CB-OE2 3.45Å; S244-E344 PolarHBondContact OG-OE2 2.92Å; E344-F346 PolarHBondContact O-N 2.87Å; E344-N347 PolarHBondContact O-N 3.48Å
345A96.3Very high84.7Confident36 Ų3666.7 Ų66.730%0.29835%0.349SS..G310 helixtrans-65.9-13.6176.700000114L248 T343 N347L248-A345 HydrophobicContact CB-CB 4.17Å; L248-A345 HydrophobicContact CD2-CB 3.96Å; T343-A345 VanDerWaalsContact C-N 3.29Å; T343-A345 PolarHBondContact O-N 3.18Å; A345-N347 VanDerWaalsContact C-N 3.33Å
346F97.3Very high87.4Confident0 Ų061 Ų610%031%0.31CS..G310 helixtrans-87.91.1-179.2-68.1-105.6000113.1L247 L248 C251 L288 W316 M317 T343 E344 E348 S349 R350L247-F346 HydrophobicContact CB-CE2 4.29Å; L247-F346 HydrophobicContact CD2-CE2 4.27Å; L247-F346 HydrophobicContact CD2-CZ 4.49Å; L247-F346 HydrophobicContact CG-CE2 4.07Å; L247-F346 HydrophobicContact CG-CZ 4.02Å; L248-F346 VanDerWaalsContact CA-CZ 3.41Å; L248-F346 HydrophobicContact CB-CD2 4.32Å; L248-F346 HydrophobicContact CB-CE1 4.5Å; L248-F346 HydrophobicContact CB-CE2 3.78Å; L248-F346 HydrophobicContact CB-CZ 3.9Å; L248-F346 HydrophobicContact CD1-CD1 3.78Å; L248-F346 HydrophobicContact CD1-CD2 4.35Å; L248-F346 HydrophobicContact CD1-CE1 3.67Å; L248-F346 HydrophobicContact CD1-CE2 4.27Å; L248-F346 HydrophobicContact CD1-CG 4.14Å; L248-F346 HydrophobicContact CD1-CZ 3.95Å; C251-F346 HydrophobicContact CB-CE1 4.3Å; C251-F346 HydrophobicContact CB-CZ 4.31Å; L288-F346 HydrophobicContact CD2-CD1 3.6Å; L288-F346 HydrophobicContact CD2-CE1 3.61Å; W316-F346 HydrophobicContact CH2-CE1 4.03Å; W316-F346 AromaticContact CH2-CZ 3.84Å; W316-F346 HydrophobicContact CH2-CZ 3.84Å; W316-F346 HydrophobicContact CZ3-CD1 4.07Å; W316-F346 AromaticContact CZ3-CE1 3.57Å; W316-F346 HydrophobicContact CZ3-CE1 3.57Å; W316-F346 AromaticContact CZ3-CZ 3.84Å; W316-F346 HydrophobicContact CZ3-CZ 3.84Å; M317-F346 HydrophobicContact CE-CD1 3.97Å; M317-F346 HydrophobicContact CG-CB 4.34Å; M317-F346 HydrophobicContact CG-CD1 4.08Å; M317-F346 HydrophobicContact CG-CG 4.48Å; M317-F346 HydrophobicContact SD-CB 4.05Å; M317-F346 HydrophobicContact SD-CD1 4.03Å; T343-F346 HydrophobicContact CG2-CD2 4.45Å; T343-F346 WeakPolarHBondContact O-CB 3.28Å; T343-F346 PolarHBondContact O-N 3.19Å; E344-F346 PolarHBondContact O-N 2.87Å; F346-E348 VanDerWaalsContact C-N 3.31Å; F346-E348 PolarHBondContact O-N 3.41Å; F346-S349 WeakPolarHBondContact O-CA 3.15Å; F346-S349 WeakPolarHBondContact O-CB 3.23Å; F346-S349 PolarHBondContact O-N 3.33Å; F346-R350 PolarHBondContact O-N 2.99Å
347N96.4Very high89.8Confident75 Ų7559 Ų5940%0.40129%0.291SS..Hα-helixtrans-55.4-42.8-172.1-171.259.3000113.8E344 A345 R350 L351E344-N347 PolarHBondContact O-N 3.48Å; A345-N347 VanDerWaalsContact C-N 3.33Å; N347-R350 PolarHBondContact O-N 2.78Å; N347-R350 PolarHBondContact OD1-NH2 2.72Å; N347-L351 WeakPolarHBondContact O-CG 3.49Å; N347-L351 PolarHBondContact O-N 3.39Å; N347-L351 VanDerWaalsContact O-N 3.1Å
348E95.8Very high91.9Very high163 Ų16359.3 Ų59.376%0.76229%0.29SS*.Hα-helixtrans-62-44.4176.3-174179176.300111.5F346 R350 L351 W352F346-E348 VanDerWaalsContact C-N 3.31Å; F346-E348 PolarHBondContact O-N 3.41Å; E348-R350 PolarHBondContact O-N 3.24Å; E348-L351 PolarHBondContact O-N 3.33Å; E348-W352 VanDerWaalsContact O-CB 3.32Å; E348-W352 WeakPolarHBondContact O-CB 3.18Å; E348-W352 PolarHBondContact O-N 3.49Å
349S96.9Very high93.6Very high16 Ų1655.5 Ų55.511%0.11227%0.268CS..Hα-helixtrans-64.5-39.1177.6-52.70000112.2L288 F346 W352 L353L288-S349 WeakPolarHBondContact CB-OG 3.48Å; F346-S349 WeakPolarHBondContact O-CA 3.15Å; F346-S349 WeakPolarHBondContact O-CB 3.23Å; F346-S349 PolarHBondContact O-N 3.33Å; S349-W352 PolarHBondContact O-N 3.11Å; S349-L353 WeakPolarHBondContact O-CB 3.41Å; S349-L353 VanDerWaalsContact O-CG 3.29Å; S349-L353 WeakPolarHBondContact O-CG 3.42Å; S349-L353 PolarHBondContact O-N 3.32Å
350R97.2Very high94.8Very high57 Ų5754.2 Ų54.222%0.21526%0.264CS..Hα-helixtrans-60.7-48.9174.8-69.1-173.5-56.3-164.50.8112L314 M317 F346 N347 E348 W352 L353 R354L314-R350 HydrophobicContact CD1-CB 4.16Å; L314-R350 HydrophobicContact CD1-CG 4.31Å; M317-R350 HydrophobicContact CB-CG 3.7Å; M317-R350 HydrophobicContact CG-CG 4.26Å; M317-R350 HydrophobicContact SD-CG 3.59Å; M317-R350 VanDerWaalsContact SD-CG 3.59Å; F346-R350 PolarHBondContact O-N 2.99Å; N347-R350 PolarHBondContact O-N 2.78Å; N347-R350 PolarHBondContact OD1-NH2 2.72Å; E348-R350 PolarHBondContact O-N 3.24Å; R350-W352 VanDerWaalsContact C-N 3.32Å; R350-W352 PolarHBondContact O-N 2.7Å; R350-L353 PolarHBondContact O-N 3.08Å; R350-R354 WeakPolarHBondContact O-CG 3.27Å; R350-R354 PolarHBondContact O-N 3.5Å
351L96.8Very high94.8Very high88 Ų8854.5 Ų54.546%0.46127%0.266SS..Hα-helixtrans-62.7-41.8178.9-68.3174.7000111.4N347 E348 R354 S355N347-L351 WeakPolarHBondContact O-CG 3.49Å; N347-L351 PolarHBondContact O-N 3.39Å; N347-L351 VanDerWaalsContact O-N 3.1Å; E348-L351 PolarHBondContact O-N 3.33Å; L351-R354 PolarHBondContact O-N 3.34Å; L351-S355 PolarHBondContact O-N 3.32Å; L351-S355 PolarHBondContact O-OG 3.43Å
352W96.9Very high93.7Very high49 Ų4958.7 Ų58.719%0.18629%0.288CS..Hα-helixtrans-62.7-45.7176.5-178.286.6000112.4L49 F50 D289 Y310 E348 S349 R350 R354 S355 C356L49-W352 PolarHBondContact O-NE1 2.93Å; F50-W352 HydrophobicContact CD1-CZ2 4.37Å; F50-W352 HydrophobicContact CE1-CH2 4.45Å; F50-W352 AromaticContact CE1-CZ2 3.62Å; F50-W352 HydrophobicContact CE1-CZ2 3.62Å; F50-W352 HydrophobicContact CZ-CZ2 4.05Å; D289-W352 HydrophobicContact CB-CE3 4.13Å; D289-W352 HydrophobicContact CB-CH2 3.63Å; D289-W352 HydrophobicContact CB-CZ2 4.47Å; D289-W352 HydrophobicContact CB-CZ3 3.42Å; D289-W352 VanDerWaalsContact CB-CZ3 3.42Å; Y310-W352 HydrophobicContact CE1-CH2 4.15Å; Y310-W352 HydrophobicContact CE1-CZ3 4Å; Y310-W352 AromaticContact CZ-CH2 3.94Å; Y310-W352 WeakPolarHBondContact OH-CH2 3.35Å; E348-W352 VanDerWaalsContact O-CB 3.32Å; E348-W352 WeakPolarHBondContact O-CB 3.18Å; E348-W352 PolarHBondContact O-N 3.49Å; S349-W352 PolarHBondContact O-N 3.11Å; R350-W352 VanDerWaalsContact C-N 3.32Å; R350-W352 PolarHBondContact O-N 2.7Å; W352-R354 PolarHBondContact O-N 3.12Å; W352-S355 PolarHBondContact O-N 3.06Å; W352-C356 WeakPolarHBondContact CZ2-SG 3.45Å; W352-C356 PolarHBondContact O-N 3.13Å; W352-C356 PolarHBondContact O-SG 3.41Å
353L97.5Very high91.7Very high0 Ų064.8 Ų64.80%033%0.33CS..Hα-helixtrans-61.1-43.6177.1-77.1170.5000111.9Y310 L313 L314 M317 S349 R350 S355 C356 L357Y310-L353 HydrophobicContact CD1-CD2 3.38Å; Y310-L353 HydrophobicContact CE1-CD2 4Å; Y310-L353 HydrophobicContact CG-CD2 3.77Å; L313-L353 HydrophobicContact CB-CD1 3.81Å; L313-L353 HydrophobicContact CB-CD2 4.45Å; L313-L353 HydrophobicContact CD1-CD2 4.44Å; L314-L353 HydrophobicContact CB-CD1 4.39Å; L314-L353 HydrophobicContact CD1-CB 4.35Å; M317-L353 HydrophobicContact CE-CD1 3.66Å; M317-L353 HydrophobicContact SD-CD1 3.93Å; S349-L353 WeakPolarHBondContact O-CB 3.41Å; S349-L353 VanDerWaalsContact O-CG 3.29Å; S349-L353 WeakPolarHBondContact O-CG 3.42Å; S349-L353 PolarHBondContact O-N 3.32Å; R350-L353 PolarHBondContact O-N 3.08Å; L353-S355 PolarHBondContact O-N 3.38Å; L353-C356 WeakPolarHBondContact O-CB 3.41Å; L353-C356 PolarHBondContact O-N 2.82Å; L353-L357 WeakPolarHBondContact O-CG 3.46Å; L353-L357 PolarHBondContact O-N 3.14Å
354R97.1Very high91.6Very high118 Ų11867.7 Ų67.745%0.44535%0.345SS..Hα-helixtrans-59.3-47175.1-71.4175.2-177.5178.4-2.3111.3L314 E318 R350 L351 W352 C356 L357 D358L314-R354 HydrophobicContact CD1-CG 4.1Å; L314-R354 HydrophobicContact CD2-CG 3.72Å; E318-R354 IonicContact OE1-CZ 3.47Å; E318-R354 VanDerWaalsContact OE1-CZ 3.31Å; E318-R354 IonicContact OE1-NE 2.72Å; E318-R354 PolarHBondContact OE1-NE 3.17Å; E318-R354 IonicContact OE1-NH2 3.67Å; E318-R354 PolarHBondContact OE1-NH2 2.86Å; R350-R354 WeakPolarHBondContact O-CG 3.27Å; R350-R354 PolarHBondContact O-N 3.5Å; L351-R354 PolarHBondContact O-N 3.34Å; W352-R354 PolarHBondContact O-N 3.12Å; R354-C356 VanDerWaalsContact C-N 3.3Å; R354-C356 PolarHBondContact O-N 3.41Å; R354-L357 WeakPolarHBondContact O-CB 3.48Å; R354-L357 PolarHBondContact O-N 3.15Å; R354-L357 VanDerWaalsContact O-N 3.16Å; R354-D358 VanDerWaalsContact O-CG 3.29Å; R354-D358 PolarHBondContact O-N 3.27Å
355S96Very high91.4Very high50 Ų5065 Ų6535%0.3533%0.334SS..Hα-helixtrans-63.1-35.3176.8-610000112.8L351 W352 L353 R359L351-S355 PolarHBondContact O-N 3.32Å; L351-S355 PolarHBondContact O-OG 3.43Å; W352-S355 PolarHBondContact O-N 3.06Å; L353-S355 PolarHBondContact O-N 3.38Å; S355-R359 WeakPolarHBondContact O-CG 3.32Å; S355-R359 PolarHBondContact O-N 2.75Å
356C96.6Very high91.1Very high0 Ų066.6 Ų66.60%034%0.336CS..Hα-helixtrans-65-43.1173.6-68.80000112.1L36 Y310 W352 L353 R354 R359 L360L36-C356 HydrophobicContact CD1-CB 4.02Å; Y310-C356 HydrophobicContact CD2-CB 3.83Å; Y310-C356 HydrophobicContact CE2-CB 3.61Å; W352-C356 WeakPolarHBondContact CZ2-SG 3.45Å; W352-C356 PolarHBondContact O-N 3.13Å; W352-C356 PolarHBondContact O-SG 3.41Å; L353-C356 WeakPolarHBondContact O-CB 3.41Å; L353-C356 PolarHBondContact O-N 2.82Å; R354-C356 VanDerWaalsContact C-N 3.3Å; R354-C356 PolarHBondContact O-N 3.41Å; C356-R359 PolarHBondContact O-N 3.23Å; C356-L360 WeakPolarHBondContact O-CG 3.41Å; C356-L360 PolarHBondContact O-N 2.75Å; C356-L360 VanDerWaalsContact O-N 3.13Å
357L96.8Very high90.8Very high13 Ų1370.5 Ų70.57%0.06836%0.356CS..Hα-helixtrans-62.5-42.8177.4-73.6166.6000111.6A307 K311 L314 L353 R354 R359 L360 E361A307-L357 HydrophobicContact CB-CD2 4.48Å; K311-L357 HydrophobicContact CD-CD2 4.46Å; K311-L357 HydrophobicContact CG-CD1 4.19Å; K311-L357 HydrophobicContact CG-CD2 3.79Å; L314-L357 HydrophobicContact CD2-CD1 3.96Å; L353-L357 WeakPolarHBondContact O-CG 3.46Å; L353-L357 PolarHBondContact O-N 3.14Å; R354-L357 WeakPolarHBondContact O-CB 3.48Å; R354-L357 PolarHBondContact O-N 3.15Å; R354-L357 VanDerWaalsContact O-N 3.16Å; L357-R359 VanDerWaalsContact C-N 3.27Å; L357-R359 PolarHBondContact O-N 2.75Å; L357-L360 HydrophobicContact CD2-CD1 4.42Å; L357-L360 WeakPolarHBondContact O-CB 3.35Å; L357-L360 PolarHBondContact O-N 2.86Å; L357-E361 WeakPolarHBondContact O-CG 3.11Å; L357-E361 PolarHBondContact O-N 3.06Å
358D93.6Very high90.4Very high95 Ų9570.3 Ų70.351%0.50835%0.353SS..Hα-helixtrans-56.6-42174.7-63.9-24.2000111.2R354 L360 E361 I362R354-D358 VanDerWaalsContact O-CG 3.29Å; R354-D358 PolarHBondContact O-N 3.27Å; D358-L360 VanDerWaalsContact C-N 3.33Å; D358-L360 PolarHBondContact O-N 3.12Å; D358-E361 PolarHBondContact O-N 2.79Å; D358-I362 WeakPolarHBondContact O-CD1 3.27Å; D358-I362 VanDerWaalsContact O-CG1 3.23Å; D358-I362 WeakPolarHBondContact O-CG1 3.22Å; D358-I362 PolarHBondContact O-N 3.3Å; D358-I362 VanDerWaalsContact O-N 3.11Å
359R90.1Very high90.1Very high85 Ų8564.1 Ų64.132%0.32133%0.326SS..Hα-helixtrans-68.8-28.9177.6-62.6-43.7-170.587.515.4114.1L36 E39 G47 L49 S355 C356 L357L36-R359 HydrophobicContact CD1-CB 4.35Å; E39-R359 IonicContact OE1-CZ 3.76Å; E39-R359 IonicContact OE1-NH1 3.62Å; E39-R359 PolarHBondContact OE1-NH1 3.05Å; E39-R359 IonicContact OE1-NH2 2.86Å; G47-R359 PolarHBondContact O-NH2 3.15Å; L49-R359 HydrophobicContact CD1-CG 3.87Å; S355-R359 WeakPolarHBondContact O-CG 3.32Å; S355-R359 PolarHBondContact O-N 2.75Å; C356-R359 PolarHBondContact O-N 3.23Å; L357-R359 VanDerWaalsContact C-N 3.27Å; L357-R359 PolarHBondContact O-N 2.75Å
360L92.4Very high89.6Confident25 Ų2567.5 Ų67.513%0.13134%0.341CS..Hα-helixtrans-75.5-29.1176.4-71.9167.4000112.1E33 L36 I306 A307 Y310 C356 L357 D358E33-L360 HydrophobicContact CB-CD2 4.41Å; E33-L360 HydrophobicContact CG-CD2 3.86Å; L36-L360 HydrophobicContact CB-CD2 3.96Å; L36-L360 HydrophobicContact CB-CG 4.42Å; L36-L360 HydrophobicContact CD2-CD1 4Å; L36-L360 HydrophobicContact CD2-CD2 3.75Å; L36-L360 HydrophobicContact CD2-CG 3.91Å; L36-L360 HydrophobicContact CG-CD2 4.45Å; I306-L360 HydrophobicContact CG2-CD1 4.07Å; A307-L360 HydrophobicContact CB-CD1 4.01Å; Y310-L360 HydrophobicContact CD2-CD1 3.84Å; Y310-L360 HydrophobicContact CE2-CD1 4.19Å; C356-L360 WeakPolarHBondContact O-CG 3.41Å; C356-L360 PolarHBondContact O-N 2.75Å; C356-L360 VanDerWaalsContact O-N 3.13Å; L357-L360 HydrophobicContact CD2-CD1 4.42Å; L357-L360 WeakPolarHBondContact O-CB 3.35Å; L357-L360 PolarHBondContact O-N 2.86Å; D358-L360 VanDerWaalsContact C-N 3.33Å; D358-L360 PolarHBondContact O-N 3.12Å
361E84.6Confident89Confident117 Ų11768.3 Ų68.355%0.54735%0.351SS..Hα-helixtrans-95.4-18.5-174.5-67.5-175173.100114.4K311 L357 D358 S363K311-E361 WeakPolarHBondContact CE-OE1 3.29Å; K311-E361 IonicContact NZ-OE1 3.84Å; K311-E361 PolarHBondContact NZ-OE1 3.11Å; L357-E361 WeakPolarHBondContact O-CG 3.11Å; L357-E361 PolarHBondContact O-N 3.06Å; D358-E361 PolarHBondContact O-N 2.79Å; E361-S363 PolarHBondContact O-N 3.12Å; E361-S363 VanDerWaalsContact O-N 3.08Å
362I68Low88.3Confident103 Ų10366.7 Ų66.753%0.52834%0.341SS..  trans-59.4114.7169.1-70.2160.4000107.4R35 D358R35-I362 PolarHBondContact NH2-O 2.97Å; D358-I362 WeakPolarHBondContact O-CD1 3.27Å; D358-I362 VanDerWaalsContact O-CG1 3.23Å; D358-I362 WeakPolarHBondContact O-CG1 3.22Å; D358-I362 PolarHBondContact O-N 3.3Å; D358-I362 VanDerWaalsContact O-N 3.11Å
363S50.5Low87.6Confident145 Ų14568.3 Ų68.3100%1.01436%0.356SS*.  trans-74.50177.855.80000111.2R35 E361R35-S363 PolarHBondContact NH1-OXT 3.36Å; R35-S363 PolarHBondContact NH2-OXT 3.23Å; E361-S363 PolarHBondContact O-N 3.12Å; E361-S363 VanDerWaalsContact O-N 3.08Å

Retrieved 363 of 363 residues in 252.6 ms (Link to these results)