A0A087YAD3_POEFO Loading...

Caspase-8

AlphaFold DB , UniProt , Accession A0A087YAD3, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 456 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M68.3Low87.7Confident78 Ų7866.7 Ų66.738%0.38433%0.333SS..  0160.60-122.5-162.8-75.300110.6R3 L6 L53 N54 L58 L74M1-R3 PolarHBondContact O-N 3Å; M1-L6 HydrophobicContact CB-CD1 4.12Å; M1-L6 HydrophobicContact CE-CD2 4.28Å; M1-L6 HydrophobicContact SD-CD2 3.9Å; M1-L53 HydrophobicContact CE-CD1 3.63Å; M1-L53 HydrophobicContact CE-CG 3.63Å; M1-N54 WeakPolarHBondContact CE-O 3.43Å; M1-L58 HydrophobicContact CE-CD1 3.23Å; M1-L58 HydrophobicContact CE-CG 3.69Å; M1-L58 HydrophobicContact SD-CD1 3.67Å; M1-L74 HydrophobicContact SD-CD2 4.39Å
2N80.5Confident88.2Confident68 Ų6867.8 Ų67.836%0.36434%0.341SS..  trans-69.1114.2-178.8-173.2-6.7000111.2P4 L5 L6 D77N2-P4 WeakPolarHBondContact OD1-CD 3.49Å; N2-P4 WeakPolarHBondContact OD1-CG 3.44Å; N2-L5 HydrophobicContact CB-CB 3.96Å; N2-L5 WeakPolarHBondContact O-CB 3.38Å; N2-L5 PolarHBondContact O-N 3.47Å; N2-L5 VanDerWaalsContact O-N 3.13Å; N2-L6 PolarHBondContact O-N 3.19Å; N2-L6 VanDerWaalsContact O-N 3.16Å; N2-D77 WeakPolarHBondContact CB-OD2 3.5Å; N2-D77 PolarHBondContact ND2-OD2 3.07Å
3R86.1Confident88.7Confident132 Ų13264 Ų6450%0.49832%0.322SS..Hα-helixtrans-60.3-46-176.4-67.7-73.3-169.7-160.6-6.2113M1 L5 L6 A7 E48M1-R3 PolarHBondContact O-N 3Å; R3-L5 VanDerWaalsContact C-N 3.29Å; R3-L5 PolarHBondContact O-N 2.68Å; R3-L6 PolarHBondContact O-N 3.35Å; R3-A7 PolarHBondContact O-N 3.2Å; R3-E48 IonicContact CZ-OE1 3.2Å; R3-E48 IonicContact CZ-OE2 2.82Å; R3-E48 IonicContact NH1-OE1 2.88Å; R3-E48 IonicContact NH1-OE2 2.86Å; R3-E48 PolarHBondContact NH1-OE2 2.92Å; R3-E48 VanDerWaalsContact NH2-CD 3.3Å; R3-E48 IonicContact NH2-OE1 2.81Å; R3-E48 PolarHBondContact NH2-OE1 3.45Å; R3-E48 IonicContact NH2-OE2 3.35Å; R3-E48 PolarHBondContact NH2-OE2 3.37Å
4P87.7Confident89Confident89 Ų8963.6 Ų63.658%0.57832%0.321SS*.Hα-helixtrans-51.4-40.3169.2-30.527.5000115.3N2 A7 R8N2-P4 WeakPolarHBondContact OD1-CD 3.49Å; N2-P4 WeakPolarHBondContact OD1-CG 3.44Å; P4-A7 PolarHBondContact O-N 2.94Å; P4-R8 WeakPolarHBondContact O-CG 3.31Å; P4-R8 PolarHBondContact O-N 3.12Å
5L88.3Confident89.1Confident15 Ų1565.9 Ų65.98%0.07935%0.345CS..Hα-helixtrans-65.6-46.6177.9178.868.4000111.1N2 R3 A7 R8 I9 L74 D77N2-L5 HydrophobicContact CB-CB 3.96Å; N2-L5 WeakPolarHBondContact O-CB 3.38Å; N2-L5 PolarHBondContact O-N 3.47Å; N2-L5 VanDerWaalsContact O-N 3.13Å; R3-L5 VanDerWaalsContact C-N 3.29Å; R3-L5 PolarHBondContact O-N 2.68Å; L5-A7 VanDerWaalsContact C-N 3.27Å; L5-A7 PolarHBondContact O-N 3.22Å; L5-R8 PolarHBondContact O-N 3.46Å; L5-R8 VanDerWaalsContact O-N 3.16Å; L5-I9 HydrophobicContact CD1-CD1 4.41Å; L5-I9 HydrophobicContact CD2-CD1 4.5Å; L5-I9 HydrophobicContact CG-CD1 3.97Å; L5-I9 WeakPolarHBondContact O-CG1 3.41Å; L5-I9 PolarHBondContact O-N 3.23Å; L5-L74 HydrophobicContact CD2-CD2 3.98Å; L5-D77 HydrophobicContact CD1-CB 4.21Å; L5-D77 HydrophobicContact CD2-CB 3.86Å; L5-D77 WeakPolarHBondContact CD2-OD2 3.37Å
6L90.9Very high89.2Confident8 Ų872.7 Ų72.74%0.04237%0.365CS..Hα-helixtrans-62.3-34.1178.8-65.3174.4000112.6M1 N2 R3 D10 F44 L53 L58M1-L6 HydrophobicContact CB-CD1 4.12Å; M1-L6 HydrophobicContact CE-CD2 4.28Å; M1-L6 HydrophobicContact SD-CD2 3.9Å; N2-L6 PolarHBondContact O-N 3.19Å; N2-L6 VanDerWaalsContact O-N 3.16Å; R3-L6 PolarHBondContact O-N 3.35Å; L6-D10 WeakPolarHBondContact O-CB 3.26Å; L6-D10 PolarHBondContact O-N 3Å; L6-F44 HydrophobicContact CB-CD2 3.98Å; L6-F44 HydrophobicContact CB-CE2 4.42Å; L6-F44 HydrophobicContact CD2-CD2 3.9Å; L6-F44 HydrophobicContact CD2-CE2 4.23Å; L6-F44 HydrophobicContact CD2-CG 4.17Å; L6-F44 HydrophobicContact CG-CD2 4.4Å; L6-L53 HydrophobicContact CD1-CD2 3.87Å; L6-L53 HydrophobicContact CD2-CD1 4.49Å; L6-L58 HydrophobicContact CD2-CD1 3.69Å
7A91.4Very high89.4Confident46 Ų4670.8 Ų70.838%0.3836%0.355SS..Hα-helixtrans-65.8-41.9174.400000111.8R3 P4 L5 D10 D11R3-A7 PolarHBondContact O-N 3.2Å; P4-A7 PolarHBondContact O-N 2.94Å; L5-A7 VanDerWaalsContact C-N 3.27Å; L5-A7 PolarHBondContact O-N 3.22Å; A7-D10 WeakPolarHBondContact O-CB 3.46Å; A7-D10 PolarHBondContact O-N 3.49Å; A7-D11 PolarHBondContact O-N 3.21Å
8R91.3Very high89.7Confident162 Ų16267.3 Ų67.361%0.61134%0.338SS*.Hα-helixtrans-65.4-40.7176.1-65.9176.477.3-174.94.4112.1P4 L5 D10 D11 D12 M73P4-R8 WeakPolarHBondContact O-CG 3.31Å; P4-R8 PolarHBondContact O-N 3.12Å; L5-R8 PolarHBondContact O-N 3.46Å; L5-R8 VanDerWaalsContact O-N 3.16Å; R8-D10 VanDerWaalsContact C-N 3.3Å; R8-D10 PolarHBondContact O-N 2.66Å; R8-D11 PolarHBondContact O-N 3.14Å; R8-D12 PolarHBondContact O-N 3.02Å; R8-M73 HydrophobicContact CB-CE 3.85Å
9I92.9Very high89.8Confident0 Ų066.5 Ų66.50%034%0.342CS..Hα-helixtrans-61-41.2174.5-69.7169.8000110.8L5 D12 L13 F44 F62 L70 M73 L74L5-I9 HydrophobicContact CD1-CD1 4.41Å; L5-I9 HydrophobicContact CD2-CD1 4.5Å; L5-I9 HydrophobicContact CG-CD1 3.97Å; L5-I9 WeakPolarHBondContact O-CG1 3.41Å; L5-I9 PolarHBondContact O-N 3.23Å; I9-D12 PolarHBondContact O-N 3.12Å; I9-L13 HydrophobicContact CG2-CD1 3.9Å; I9-L13 WeakPolarHBondContact O-CD1 3.2Å; I9-L13 WeakPolarHBondContact O-CG 3.49Å; I9-L13 PolarHBondContact O-N 3.2Å; I9-F44 HydrophobicContact CB-CE2 4.38Å; I9-F44 HydrophobicContact CG2-CE2 3.91Å; I9-F44 HydrophobicContact CG2-CZ 3.61Å; I9-F62 HydrophobicContact CD1-CE2 4.17Å; I9-F62 HydrophobicContact CG2-CE1 4.36Å; I9-F62 HydrophobicContact CG2-CE2 4.1Å; I9-F62 HydrophobicContact CG2-CZ 3.51Å; I9-L70 HydrophobicContact CG1-CD2 4.45Å; I9-L70 HydrophobicContact CG2-CD1 4.38Å; I9-M73 HydrophobicContact CG1-CE 4.43Å; I9-L74 HydrophobicContact CD1-CD2 3.75Å; I9-L74 HydrophobicContact CD1-CG 4.26Å
10D94.6Very high90Very high10 Ų1065.1 Ų65.15%0.05333%0.334CS..Hα-helixtrans-63.5-40.4176.4179.565.5000112.7L6 A7 R8 D12 L13 F39 A40 R41L6-D10 WeakPolarHBondContact O-CB 3.26Å; L6-D10 PolarHBondContact O-N 3Å; A7-D10 WeakPolarHBondContact O-CB 3.46Å; A7-D10 PolarHBondContact O-N 3.49Å; R8-D10 VanDerWaalsContact C-N 3.3Å; R8-D10 PolarHBondContact O-N 2.66Å; D10-D12 PolarHBondContact O-N 3.48Å; D10-L13 PolarHBondContact O-N 3.39Å; D10-F39 WeakPolarHBondContact OD1-CB 3.49Å; D10-A40 HydrophobicContact CB-CB 4.21Å; D10-A40 WeakPolarHBondContact OD1-CA 3.23Å; D10-A40 WeakPolarHBondContact OD1-CB 3.15Å; D10-A40 PolarHBondContact OD1-N 3.38Å; D10-R41 HydrophobicContact CB-CB 4.21Å; D10-R41 PolarHBondContact OD1-N 2.69Å; D10-R41 WeakPolarHBondContact OD2-CD 3.45Å; D10-R41 WeakPolarHBondContact OD2-CG 3.19Å; D10-R41 IonicContact OD2-CZ 3.97Å; D10-R41 IonicContact OD2-NE 3.19Å; D10-R41 IonicContact OD2-NH1 3.37Å; D10-R41 PolarHBondContact OD2-NH1 2.92Å
11D93.3Very high90.2Very high126 Ų12662 Ų6267%0.67432%0.318SS*.Hα-helixtrans-64.8-27.2177-68.2-29.6000112.9A7 R8A7-D11 PolarHBondContact O-N 3.21Å; R8-D11 PolarHBondContact O-N 3.14Å
12D93.6Very high91.4Very high80 Ų8058.9 Ų58.943%0.42830%0.304SS..THydrogen-bonded Turntrans-94.14.2-177.6-76.9-31000113.6R8 I9 D10 R67 L70R8-D12 PolarHBondContact O-N 3.02Å; I9-D12 PolarHBondContact O-N 3.12Å; D10-D12 PolarHBondContact O-N 3.48Å; D12-R67 VanDerWaalsContact O-CZ 3.28Å; D12-R67 PolarHBondContact O-NH1 3.13Å; D12-R67 PolarHBondContact O-NH2 2.83Å; D12-L70 HydrophobicContact CB-CD2 3.78Å
13L93.9Very high92.1Very high18 Ų1856.3 Ų56.39%0.09429%0.29CS..  trans-110.5126.9178.7-76163.9000111.6I9 D10 E17 V18 L21 A40 F44 F62 L70I9-L13 HydrophobicContact CG2-CD1 3.9Å; I9-L13 WeakPolarHBondContact O-CD1 3.2Å; I9-L13 WeakPolarHBondContact O-CG 3.49Å; I9-L13 PolarHBondContact O-N 3.2Å; D10-L13 PolarHBondContact O-N 3.39Å; L13-E17 WeakPolarHBondContact CA-OE2 3.35Å; L13-E17 HydrophobicContact CD2-CB 3.73Å; L13-V18 HydrophobicContact CB-CG2 4.12Å; L13-L21 HydrophobicContact CD1-CD1 3.69Å; L13-L21 HydrophobicContact CD2-CD1 4.06Å; L13-A40 HydrophobicContact CB-CB 4.4Å; L13-A40 HydrophobicContact CD1-CB 3.52Å; L13-F44 HydrophobicContact CD1-CZ 4.4Å; L13-F62 HydrophobicContact CD1-CE1 4.42Å; L13-L70 HydrophobicContact CD1-CD1 4.26Å; L13-L70 HydrophobicContact CD2-CD1 3.7Å; L13-L70 HydrophobicContact CG-CD1 3.86Å
14D93.6Very high92.4Very high58 Ų5850.1 Ų50.131%0.3127%0.267SS..  trans-81.4169.9173.990.712.2000112.5R16 E17 V18D14-R16 PolarHBondContact O-N 3.32Å; D14-R16 WeakPolarHBondContact OD1-CA 3.41Å; D14-R16 VanDerWaalsContact OD1-CB 3.29Å; D14-R16 WeakPolarHBondContact OD1-CB 3.23Å; D14-R16 PolarHBondContact OD1-N 2.59Å; D14-R16 IonicContact OD1-NE 2.88Å; D14-R16 IonicContact OD2-CZ 2.67Å; D14-R16 IonicContact OD2-NE 2.68Å; D14-R16 PolarHBondContact OD2-NE 3.26Å; D14-R16 IonicContact OD2-NH2 3.82Å; D14-R16 PolarHBondContact OD2-NH2 2.9Å; D14-E17 PolarHBondContact N-OE2 3.24Å; D14-E17 PolarHBondContact O-N 3.17Å; D14-E17 PolarHBondContact OD1-N 3.25Å; D14-V18 VanDerWaalsContact O-CG2 3.32Å; D14-V18 WeakPolarHBondContact O-CG2 3.4Å; D14-V18 PolarHBondContact O-N 3.16Å
15S90.8Very high92.6Very high98 Ų9845.9 Ų45.969%0.68524%0.239SC*.Hα-helixtrans-65.8-23.4-176.858.90000114.4A19S15-A19 PolarHBondContact O-N 3.29Å
16R90.3Very high92.6Very high175 Ų17546.9 Ų46.966%0.6625%0.248SC*.Hα-helixtrans-76.7-45174.5-65174.5-70.3-179.20.4109.9D14 V18 A19 E20D14-R16 PolarHBondContact O-N 3.32Å; D14-R16 WeakPolarHBondContact OD1-CA 3.41Å; D14-R16 VanDerWaalsContact OD1-CB 3.29Å; D14-R16 WeakPolarHBondContact OD1-CB 3.23Å; D14-R16 PolarHBondContact OD1-N 2.59Å; D14-R16 IonicContact OD1-NE 2.88Å; D14-R16 IonicContact OD2-CZ 2.67Å; D14-R16 IonicContact OD2-NE 2.68Å; D14-R16 PolarHBondContact OD2-NE 3.26Å; D14-R16 IonicContact OD2-NH2 3.82Å; D14-R16 PolarHBondContact OD2-NH2 2.9Å; R16-V18 VanDerWaalsContact C-N 3.32Å; R16-V18 PolarHBondContact O-N 2.9Å; R16-A19 WeakPolarHBondContact O-CA 3.41Å; R16-A19 WeakPolarHBondContact O-CB 3.38Å; R16-A19 PolarHBondContact O-N 2.92Å; R16-E20 WeakPolarHBondContact O-CG 3.31Å; R16-E20 PolarHBondContact O-N 2.98Å
17E92.8Very high92.4Very high40 Ų4050.2 Ų50.219%0.18727%0.265CS..Hα-helixtrans-63.2-39.4177.2-62.7175.6122.600111.4L13 D14 A19 E20 L21 R67L13-E17 WeakPolarHBondContact CA-OE2 3.35Å; L13-E17 HydrophobicContact CD2-CB 3.73Å; D14-E17 PolarHBondContact N-OE2 3.24Å; D14-E17 PolarHBondContact O-N 3.17Å; D14-E17 PolarHBondContact OD1-N 3.25Å; E17-A19 VanDerWaalsContact C-N 3.3Å; E17-A19 PolarHBondContact O-N 2.71Å; E17-E20 WeakPolarHBondContact O-CB 3.26Å; E17-E20 PolarHBondContact O-N 2.76Å; E17-L21 VanDerWaalsContact O-CG 3.29Å; E17-L21 WeakPolarHBondContact O-CG 3.27Å; E17-L21 PolarHBondContact O-N 3.35Å; E17-R67 VanDerWaalsContact OE1-CD 3.27Å; E17-R67 WeakPolarHBondContact OE1-CD 3.49Å; E17-R67 IonicContact OE1-CZ 2.96Å; E17-R67 IonicContact OE1-NE 3.18Å; E17-R67 IonicContact OE1-NH1 3.57Å; E17-R67 PolarHBondContact OE1-NH1 3.37Å; E17-R67 IonicContact OE2-NH1 2.8Å; E17-R67 PolarHBondContact OE2-NH1 3.02Å
18V93.8Very high92.1Very high8 Ų849.4 Ų49.45%0.04826%0.255CS..Hα-helixtrans-60.4-41.1172.2173.40000111.3L13 D14 R16 L21 C22 I37 A40L13-V18 HydrophobicContact CB-CG2 4.12Å; D14-V18 VanDerWaalsContact O-CG2 3.32Å; D14-V18 WeakPolarHBondContact O-CG2 3.4Å; D14-V18 PolarHBondContact O-N 3.16Å; R16-V18 VanDerWaalsContact C-N 3.32Å; R16-V18 PolarHBondContact O-N 2.9Å; V18-L21 PolarHBondContact O-N 3.08Å; V18-C22 WeakPolarHBondContact O-CB 3.1Å; V18-C22 PolarHBondContact O-N 2.96Å; V18-C22 PolarHBondContact O-SG 3.4Å; V18-I37 HydrophobicContact CG1-CG2 4.01Å; V18-A40 HydrophobicContact CG2-CB 4.03Å
19A92.1Very high91.9Very high52 Ų5241.7 Ų41.743%0.4323%0.227SC..Hα-helixtrans-66.6-37.7177.600000112.2S15 R16 E17 C22 F23S15-A19 PolarHBondContact O-N 3.29Å; R16-A19 WeakPolarHBondContact O-CA 3.41Å; R16-A19 WeakPolarHBondContact O-CB 3.38Å; R16-A19 PolarHBondContact O-N 2.92Å; E17-A19 VanDerWaalsContact C-N 3.3Å; E17-A19 PolarHBondContact O-N 2.71Å; A19-C22 WeakPolarHBondContact O-CB 3.5Å; A19-C22 PolarHBondContact O-N 3.47Å; A19-F23 PolarHBondContact O-N 2.88Å
20E94.4Very high91.5Very high38 Ų3845.3 Ų45.318%0.17825%0.246CC..Hα-helixtrans-62.6-45.8173.1-73.4174-152.700112.2R16 E17 C22 F23 L24 T65 Y99 L133R16-E20 WeakPolarHBondContact O-CG 3.31Å; R16-E20 PolarHBondContact O-N 2.98Å; E17-E20 WeakPolarHBondContact O-CB 3.26Å; E17-E20 PolarHBondContact O-N 2.76Å; E20-C22 VanDerWaalsContact C-N 3.31Å; E20-C22 PolarHBondContact O-N 3.19Å; E20-F23 WeakPolarHBondContact O-CB 3.44Å; E20-F23 PolarHBondContact O-N 3.49Å; E20-L24 WeakPolarHBondContact O-CG 3.46Å; E20-L24 PolarHBondContact O-N 3.26Å; E20-T65 HydrophobicContact CB-CG2 4.48Å; E20-Y99 HydrophobicContact CB-CE2 3.98Å; E20-Y99 HydrophobicContact CG-CE2 4.03Å; E20-Y99 PolarHBondContact OE2-OH 3.49Å; E20-L133 HydrophobicContact CB-CD1 4.47Å; E20-L133 HydrophobicContact CG-CD1 3.89Å
21L94.5Very high90.9Very high0 Ų048.8 Ų48.80%026%0.258CS..Hα-helixtrans-61.5-40.6174.9-66.3176.9000111.5L13 E17 V18 L24 C25 L43 L61 F62 T65L13-L21 HydrophobicContact CD1-CD1 3.69Å; L13-L21 HydrophobicContact CD2-CD1 4.06Å; E17-L21 VanDerWaalsContact O-CG 3.29Å; E17-L21 WeakPolarHBondContact O-CG 3.27Å; E17-L21 PolarHBondContact O-N 3.35Å; V18-L21 PolarHBondContact O-N 3.08Å; L21-L24 PolarHBondContact O-N 3.22Å; L21-C25 WeakPolarHBondContact O-CB 3.26Å; L21-C25 PolarHBondContact O-N 2.86Å; L21-C25 PolarHBondContact O-SG 3.1Å; L21-L43 HydrophobicContact CB-CD2 3.65Å; L21-L61 HydrophobicContact CD2-CB 3.8Å; L21-L61 HydrophobicContact CD2-CD1 4.39Å; L21-L61 HydrophobicContact CD2-CD2 3.98Å; L21-L61 HydrophobicContact CD2-CG 4.29Å; L21-F62 HydrophobicContact CD1-CE1 4.21Å; L21-F62 HydrophobicContact CD2-CD1 4.44Å; L21-F62 HydrophobicContact CD2-CE1 4.37Å; L21-T65 HydrophobicContact CD2-CG2 3.83Å
22C93.4Very high90.5Very high13 Ų1350.8 Ų50.89%0.08826%0.261CS..Hα-helixtrans-62.6-42.4174.5-700000111.7V18 A19 E20 C25 S26 L34V18-C22 WeakPolarHBondContact O-CB 3.1Å; V18-C22 PolarHBondContact O-N 2.96Å; V18-C22 PolarHBondContact O-SG 3.4Å; A19-C22 WeakPolarHBondContact O-CB 3.5Å; A19-C22 PolarHBondContact O-N 3.47Å; E20-C22 VanDerWaalsContact C-N 3.31Å; E20-C22 PolarHBondContact O-N 3.19Å; C22-C25 PolarHBondContact O-N 3.27Å; C22-S26 PolarHBondContact O-N 2.98Å; C22-S26 PolarHBondContact O-OG 3.16Å; C22-L34 HydrophobicContact CB-CD2 4.1Å; C22-L34 WeakPolarHBondContact O-CD1 3.29Å
23F94.1Very high90.2Very high14 Ų1449.2 Ų49.26%0.06125%0.251CS..Hα-helixtrans-58.6-49.6175.1176.3-88.7000111.1A19 E20 C25 S26 R95 L98 L133 F136A19-F23 PolarHBondContact O-N 2.88Å; E20-F23 WeakPolarHBondContact O-CB 3.44Å; E20-F23 PolarHBondContact O-N 3.49Å; F23-C25 PolarHBondContact O-N 2.78Å; F23-S26 WeakPolarHBondContact O-CB 3.41Å; F23-S26 PolarHBondContact O-N 3.24Å; F23-S26 VanDerWaalsContact O-N 3.11Å; F23-S26 PolarHBondContact O-OG 3.47Å; F23-S26 VanDerWaalsContact O-OG 3.05Å; F23-R95 WeakPolarHBondContact O-CD 3.49Å; F23-L98 HydrophobicContact CE1-CB 3.98Å; F23-L98 HydrophobicContact CZ-CB 3.72Å; F23-L98 HydrophobicContact CZ-CD1 3.73Å; F23-L98 HydrophobicContact CZ-CG 4.39Å; F23-L133 HydrophobicContact CB-CD1 4.18Å; F23-L133 HydrophobicContact CD1-CD1 4.19Å; F23-L133 HydrophobicContact CD1-CD2 3.69Å; F23-L133 HydrophobicContact CD1-CG 4.4Å; F23-L133 HydrophobicContact CD2-CB 3.95Å; F23-L133 HydrophobicContact CD2-CD2 4.22Å; F23-L133 HydrophobicContact CE1-CD2 3.57Å; F23-L133 HydrophobicContact CE2-CB 4.25Å; F23-L133 HydrophobicContact CE2-CD2 4.1Å; F23-L133 HydrophobicContact CG-CB 4.18Å; F23-L133 HydrophobicContact CG-CD1 4.09Å; F23-L133 HydrophobicContact CG-CD2 4.03Å; F23-L133 HydrophobicContact CG-CG 4.33Å; F23-L133 HydrophobicContact CZ-CD2 3.77Å; F23-F136 HydrophobicContact CE2-CB 4.36Å
24L92.7Very high89.9Confident2 Ų249.1 Ų49.11%0.0125%0.25CS..Hα-helixtrans-61.4-33.3178.8-69.3173.8000112.3E20 L21 S26 L61 T64 T65 L91 R95 Y99E20-L24 WeakPolarHBondContact O-CG 3.46Å; E20-L24 PolarHBondContact O-N 3.26Å; L21-L24 PolarHBondContact O-N 3.22Å; L24-S26 VanDerWaalsContact C-N 3.31Å; L24-S26 PolarHBondContact O-N 3.02Å; L24-L61 HydrophobicContact CB-CD2 3.71Å; L24-L61 HydrophobicContact CD1-CD2 3.98Å; L24-T64 HydrophobicContact CD1-CG2 3.71Å; L24-T64 HydrophobicContact CD2-CG2 4.01Å; L24-T65 HydrophobicContact CD1-CG2 3.88Å; L24-L91 HydrophobicContact CB-CD1 4.37Å; L24-L91 HydrophobicContact CB-CD2 4.06Å; L24-L91 HydrophobicContact CD1-CD1 4.27Å; L24-L91 HydrophobicContact CD2-CD1 4.39Å; L24-R95 HydrophobicContact CD2-CB 4.33Å; L24-Y99 HydrophobicContact CD1-CD2 4.21Å; L24-Y99 HydrophobicContact CD1-CE2 4.32Å; L24-Y99 HydrophobicContact CD2-CD2 3.88Å; L24-Y99 HydrophobicContact CD2-CG 3.96Å; L24-Y99 HydrophobicContact CG-CD2 4.08Å
25C91.6Very high89.5Confident0 Ų052.4 Ų52.40%026%0.264CS..G310 helixtrans-83.33.9178.3-640000114.7L21 C22 F23 D27 V28 I29 L43 L47L21-C25 WeakPolarHBondContact O-CB 3.26Å; L21-C25 PolarHBondContact O-N 2.86Å; L21-C25 PolarHBondContact O-SG 3.1Å; C22-C25 PolarHBondContact O-N 3.27Å; F23-C25 PolarHBondContact O-N 2.78Å; C25-D27 PolarHBondContact O-N 3.06Å; C25-D27 VanDerWaalsContact O-N 3.15Å; C25-V28 PolarHBondContact O-N 3.43Å; C25-I29 HydrophobicContact CB-CD1 4.41Å; C25-I29 PolarHBondContact O-N 3.27Å; C25-L43 HydrophobicContact CB-CD1 4.19Å; C25-L47 HydrophobicContact CB-CD2 4.47Å
26S89.5Confident89.4Confident37 Ų3755 Ų5526%0.25927%0.265SS..G310 helixtrans-67.1-14.9-173.4-680000115.3C22 F23 L24 L34C22-S26 PolarHBondContact O-N 2.98Å; C22-S26 PolarHBondContact O-OG 3.16Å; F23-S26 WeakPolarHBondContact O-CB 3.41Å; F23-S26 PolarHBondContact O-N 3.24Å; F23-S26 VanDerWaalsContact O-N 3.11Å; F23-S26 PolarHBondContact O-OG 3.47Å; F23-S26 VanDerWaalsContact O-OG 3.05Å; L24-S26 VanDerWaalsContact C-N 3.31Å; L24-S26 PolarHBondContact O-N 3.02Å; S26-L34 WeakPolarHBondContact OG-CD1 3.29Å
27D85.6Confident89.4Confident77 Ų7747.7 Ų47.741%0.41224%0.239SC..G310 helixtrans-87.4-13.6173.5-63-10.7000112.5C25 S92 R95C25-D27 PolarHBondContact O-N 3.06Å; C25-D27 VanDerWaalsContact O-N 3.15Å; D27-S92 VanDerWaalsContact OD2-CB 3.24Å; D27-S92 WeakPolarHBondContact OD2-CB 3.06Å; D27-S92 PolarHBondContact OD2-OG 2.78Å; D27-R95 IonicContact OD1-CZ 3.83Å; D27-R95 VanDerWaalsContact OD1-CZ 3.32Å; D27-R95 IonicContact OD1-NE 3.57Å; D27-R95 PolarHBondContact OD1-NE 3.44Å; D27-R95 IonicContact OD1-NH2 2.85Å; D27-R95 PolarHBondContact OD1-NH2 3.11Å; D27-R95 VanDerWaalsContact OD2-CG 3.25Å; D27-R95 WeakPolarHBondContact OD2-CG 3.32Å; D27-R95 IonicContact OD2-NE 3.4Å
28V85.3Confident89.4Confident29 Ų2953.5 Ų53.518%0.17626%0.264CS..THydrogen-bonded Turntrans-106.5-42.4-174.8176.40000111.3C25 L47 F52C25-V28 PolarHBondContact O-N 3.43Å; V28-L47 HydrophobicContact CG1-CD2 4.1Å; V28-F52 HydrophobicContact CG1-CB 3.9Å; V28-F52 HydrophobicContact CG1-CD1 3.77Å; V28-F52 HydrophobicContact CG1-CD2 3.26Å; V28-F52 HydrophobicContact CG1-CE1 4.06Å; V28-F52 HydrophobicContact CG1-CE2 3.59Å; V28-F52 HydrophobicContact CG1-CG 3.35Å; V28-F52 HydrophobicContact CG1-CZ 3.98Å; V28-F52 HydrophobicContact CG2-CD1 4.06Å; V28-F52 HydrophobicContact CG2-CE1 3.98Å; V28-F52 HydrophobicContact CG2-CG 4.48Å; V28-F52 HydrophobicContact CG2-CZ 4.36Å
29I86.3Confident89.4Confident1 Ų157.7 Ų57.71%0.00528%0.282CS..SBendtrans-109.3138.1179.7-60168.7000108.3C25 Q33 L34 L43 K46 L47C25-I29 HydrophobicContact CB-CD1 4.41Å; C25-I29 PolarHBondContact O-N 3.27Å; I29-Q33 HydrophobicContact CG2-CB 3.76Å; I29-L34 HydrophobicContact CB-CD1 4.22Å; I29-L34 HydrophobicContact CB-CD2 3.78Å; I29-L34 HydrophobicContact CB-CG 3.93Å; I29-L34 HydrophobicContact CD1-CD2 4.06Å; I29-L34 HydrophobicContact CG2-CD1 4.48Å; I29-L34 HydrophobicContact CG2-CD2 3.74Å; I29-L34 HydrophobicContact CG2-CG 3.73Å; I29-L34 WeakPolarHBondContact O-CD1 3.36Å; I29-L43 HydrophobicContact CD1-CD1 3.49Å; I29-L43 VanDerWaalsContact CD1-CD1 3.49Å; I29-K46 HydrophobicContact CD1-CB 3.65Å; I29-K46 HydrophobicContact CG1-CB 4.34Å; I29-K46 HydrophobicContact CG2-CB 4.37Å; I29-L47 HydrophobicContact CD1-CD2 3.62Å; I29-L47 HydrophobicContact CD1-CG 3.8Å; I29-L47 HydrophobicContact CG1-CD2 4.17Å
30N85.3Confident89.5Confident75 Ų7555.2 Ų55.240%0.40126%0.261SS..  trans-66.8146.5179.975.253.8000110.9K32 Q33 L34N30-K32 VanDerWaalsContact C-N 3.29Å; N30-K32 PolarHBondContact O-N 3.11Å; N30-K32 PolarHBondContact OD1-N 2.92Å; N30-Q33 PolarHBondContact ND2-OE1 2.73Å; N30-Q33 WeakPolarHBondContact O-CB 3.25Å; N30-Q33 PolarHBondContact O-N 3.34Å; N30-Q33 VanDerWaalsContact O-N 3.08Å; N30-Q33 WeakPolarHBondContact OD1-CB 3.13Å; N30-Q33 WeakPolarHBondContact OD1-CG 3.45Å; N30-Q33 PolarHBondContact OD1-N 2.87Å; N30-L34 PolarHBondContact O-N 3.43Å; N30-L34 VanDerWaalsContact O-N 3.16Å
31R82.3Confident89.5Confident84 Ų8458.5 Ų58.532%0.31727%0.272SS..Hα-helixtrans-56.2-38.8-175-176.9176.8170.1152.36.5114.2Q33 L34 E35 A137 E138R31-Q33 VanDerWaalsContact C-N 3.29Å; R31-Q33 PolarHBondContact O-N 3.42Å; R31-L34 PolarHBondContact O-N 3.28Å; R31-L34 VanDerWaalsContact O-N 3.15Å; R31-E35 HydrophobicContact CG-CG 4.48Å; R31-E35 IonicContact CZ-OE1 3.98Å; R31-E35 IonicContact NE-OE1 2.71Å; R31-E35 PolarHBondContact NE-OE1 3.04Å; R31-E35 IonicContact NH2-OE1 2.61Å; R31-E35 WeakPolarHBondContact O-CG 3.28Å; R31-E35 PolarHBondContact O-N 2.96Å; R31-A137 PolarHBondContact NH1-O 3.36Å; R31-E138 IonicContact CZ-OE1 3.85Å; R31-E138 IonicContact NH2-OE1 3.96Å; R31-E138 PolarHBondContact NH2-OE1 3.25Å
32K85.2Confident89.5Confident168 Ų16861.3 Ų61.373%0.7329%0.287SS*.Hα-helixtrans-61.5-39.7179.5-69.5-174.4178.9-178.80111.7N30N30-K32 VanDerWaalsContact C-N 3.29Å; N30-K32 PolarHBondContact O-N 3.11Å; N30-K32 PolarHBondContact OD1-N 2.92Å
33Q87.1Confident89.6Confident47 Ų4760.7 Ų60.722%0.2228%0.283CS..Hα-helixtrans-69.5-36.4176.1-73.1174.8-32.900111.8I29 N30 R31 E36I29-Q33 HydrophobicContact CG2-CB 3.76Å; N30-Q33 PolarHBondContact ND2-OE1 2.73Å; N30-Q33 WeakPolarHBondContact O-CB 3.25Å; N30-Q33 PolarHBondContact O-N 3.34Å; N30-Q33 VanDerWaalsContact O-N 3.08Å; N30-Q33 WeakPolarHBondContact OD1-CB 3.13Å; N30-Q33 WeakPolarHBondContact OD1-CG 3.45Å; N30-Q33 PolarHBondContact OD1-N 2.87Å; R31-Q33 VanDerWaalsContact C-N 3.29Å; R31-Q33 PolarHBondContact O-N 3.42Å; Q33-E36 PolarHBondContact O-N 2.95Å
34L87.9Confident89.6Confident15 Ų1560.2 Ų60.28%0.07928%0.28CS..Hα-helixtrans-68.9-33.5178.3-67.8172.1000112.9C22 S26 I29 N30 R31 E36 I37 L43C22-L34 HydrophobicContact CB-CD2 4.1Å; C22-L34 WeakPolarHBondContact O-CD1 3.29Å; S26-L34 WeakPolarHBondContact OG-CD1 3.29Å; I29-L34 HydrophobicContact CB-CD1 4.22Å; I29-L34 HydrophobicContact CB-CD2 3.78Å; I29-L34 HydrophobicContact CB-CG 3.93Å; I29-L34 HydrophobicContact CD1-CD2 4.06Å; I29-L34 HydrophobicContact CG2-CD1 4.48Å; I29-L34 HydrophobicContact CG2-CD2 3.74Å; I29-L34 HydrophobicContact CG2-CG 3.73Å; I29-L34 WeakPolarHBondContact O-CD1 3.36Å; N30-L34 PolarHBondContact O-N 3.43Å; N30-L34 VanDerWaalsContact O-N 3.16Å; R31-L34 PolarHBondContact O-N 3.28Å; R31-L34 VanDerWaalsContact O-N 3.15Å; L34-E36 PolarHBondContact O-N 3.39Å; L34-I37 HydrophobicContact CD2-CD1 3.65Å; L34-I37 PolarHBondContact O-N 2.78Å; L34-L43 HydrophobicContact CD2-CD1 3.82Å
35E85.1Confident89.6Confident128 Ų12863 Ų6360%0.59830%0.297SS*.THydrogen-bonded Turntrans-65.6-19.7176.7-73.1173.8-171.700113.2R31R31-E35 HydrophobicContact CG-CG 4.48Å; R31-E35 IonicContact CZ-OE1 3.98Å; R31-E35 IonicContact NE-OE1 2.71Å; R31-E35 PolarHBondContact NE-OE1 3.04Å; R31-E35 IonicContact NH2-OE1 2.61Å; R31-E35 WeakPolarHBondContact O-CG 3.28Å; R31-E35 PolarHBondContact O-N 2.96Å
36E88.1Confident89.6Confident151 Ų15165.4 Ų65.471%0.70631%0.308SS*.THydrogen-bonded Turntrans-89.5-14.6178.3-66.1179.2171.700113.5Q33 L34Q33-E36 PolarHBondContact O-N 2.95Å; L34-E36 PolarHBondContact O-N 3.39Å
37I91.6Very high89.6Confident23 Ų2363.6 Ų63.612%0.11830%0.295CS..  trans-74.5128.2-176-69.1171.3000110.2V18 L34 F39 D42 L43 K46V18-I37 HydrophobicContact CG1-CG2 4.01Å; L34-I37 HydrophobicContact CD2-CD1 3.65Å; L34-I37 PolarHBondContact O-N 2.78Å; I37-F39 WeakPolarHBondContact CG2-O 3.29Å; I37-D42 HydrophobicContact CG1-CB 4.25Å; I37-D42 HydrophobicContact CG2-CB 4.21Å; I37-L43 HydrophobicContact CD1-CB 3.99Å; I37-L43 HydrophobicContact CD1-CD1 3.71Å; I37-L43 HydrophobicContact CD1-CG 4.48Å; I37-L43 HydrophobicContact CG2-CB 4.11Å; I37-K46 HydrophobicContact CD1-CG 4.45Å
38K91Very high89.7Confident161 Ų16163.4 Ų63.470%0.729%0.292SS*.  trans-116.6-29.3175.4-65.7-177.5-177.6177.60112.8D42K38-D42 PolarHBondContact N-OD2 3.14Å
39F94.8Very high89.8Confident97 Ų9767.4 Ų67.443%0.42531%0.309SS..SBendtrans-122.5151.2-178.5-57.1-81.7000110.3D10 I37 R41 D42 L43D10-F39 WeakPolarHBondContact OD1-CB 3.49Å; I37-F39 WeakPolarHBondContact CG2-O 3.29Å; F39-R41 HydrophobicContact CB-CG 3.77Å; F39-R41 VanDerWaalsContact CG-NH2 3.27Å; F39-R41 PolarHBondContact O-N 3.48Å; F39-D42 PolarHBondContact N-OD2 3.11Å; F39-D42 VanDerWaalsContact N-OD2 3.08Å; F39-D42 WeakPolarHBondContact O-CB 3.48Å; F39-D42 PolarHBondContact O-N 2.88Å; F39-L43 PolarHBondContact O-N 3.45Å
40A94.2Very high89.5Confident0 Ų072.2 Ų72.20%033%0.33CS..Hα-helixtrans-60.5-33.4179.100000111.7D10 L13 V18 D42 L43 F44D10-A40 HydrophobicContact CB-CB 4.21Å; D10-A40 WeakPolarHBondContact OD1-CA 3.23Å; D10-A40 WeakPolarHBondContact OD1-CB 3.15Å; D10-A40 PolarHBondContact OD1-N 3.38Å; L13-A40 HydrophobicContact CB-CB 4.4Å; L13-A40 HydrophobicContact CD1-CB 3.52Å; V18-A40 HydrophobicContact CG2-CB 4.03Å; A40-D42 PolarHBondContact O-N 2.92Å; A40-L43 CarbonylContact O-C 3.6Å; A40-L43 WeakPolarHBondContact O-CA 3.44Å; A40-L43 WeakPolarHBondContact O-CB 3.5Å; A40-L43 PolarHBondContact O-N 3.15Å; A40-L43 VanDerWaalsContact O-N 3.1Å; A40-F44 HydrophobicContact CB-CE1 4.4Å; A40-F44 HydrophobicContact CB-CE2 3.81Å; A40-F44 HydrophobicContact CB-CZ 3.69Å; A40-F44 WeakPolarHBondContact O-CD1 3.44Å; A40-F44 VanDerWaalsContact O-CD2 3.27Å; A40-F44 WeakPolarHBondContact O-CD2 3.21Å; A40-F44 WeakPolarHBondContact O-CG 3.26Å; A40-F44 PolarHBondContact O-N 2.82Å
41R93.9Very high89.3Confident107 Ų10771.8 Ų71.840%0.40434%0.343SS..Hα-helixtrans-57.1-35.8173.363.1-179.6176-104.3-1.4113.2D10 F39 F44 V45D10-R41 HydrophobicContact CB-CB 4.21Å; D10-R41 PolarHBondContact OD1-N 2.69Å; D10-R41 WeakPolarHBondContact OD2-CD 3.45Å; D10-R41 WeakPolarHBondContact OD2-CG 3.19Å; D10-R41 IonicContact OD2-CZ 3.97Å; D10-R41 IonicContact OD2-NE 3.19Å; D10-R41 IonicContact OD2-NH1 3.37Å; D10-R41 PolarHBondContact OD2-NH1 2.92Å; F39-R41 HydrophobicContact CB-CG 3.77Å; F39-R41 VanDerWaalsContact CG-NH2 3.27Å; F39-R41 PolarHBondContact O-N 3.48Å; R41-F44 PolarHBondContact O-N 2.84Å; R41-V45 WeakPolarHBondContact O-CG2 3.27Å; R41-V45 PolarHBondContact O-N 3.35Å
42D94.8Very high89.1Confident59 Ų5971.5 Ų71.532%0.31634%0.344SS..Hα-helixtrans-68.7-41.1178.4-51.7-39.2000109.5I37 K38 F39 A40 V45 K46I37-D42 HydrophobicContact CG1-CB 4.25Å; I37-D42 HydrophobicContact CG2-CB 4.21Å; K38-D42 PolarHBondContact N-OD2 3.14Å; F39-D42 PolarHBondContact N-OD2 3.11Å; F39-D42 VanDerWaalsContact N-OD2 3.08Å; F39-D42 WeakPolarHBondContact O-CB 3.48Å; F39-D42 PolarHBondContact O-N 2.88Å; A40-D42 PolarHBondContact O-N 2.92Å; D42-V45 PolarHBondContact O-N 2.98Å; D42-K46 WeakPolarHBondContact O-CG 3.45Å; D42-K46 PolarHBondContact O-N 2.6Å; D42-K46 VanDerWaalsContact O-N 3.13Å
43L94.7Very high89.1Confident0 Ų064.5 Ų64.50%031%0.314CS..Hα-helixtrans-61.1-44.3172.5-17963.6000111.9L21 C25 I29 L34 I37 F39 A40 V45 K46 L47L21-L43 HydrophobicContact CB-CD2 3.65Å; C25-L43 HydrophobicContact CB-CD1 4.19Å; I29-L43 HydrophobicContact CD1-CD1 3.49Å; I29-L43 VanDerWaalsContact CD1-CD1 3.49Å; L34-L43 HydrophobicContact CD2-CD1 3.82Å; I37-L43 HydrophobicContact CD1-CB 3.99Å; I37-L43 HydrophobicContact CD1-CD1 3.71Å; I37-L43 HydrophobicContact CD1-CG 4.48Å; I37-L43 HydrophobicContact CG2-CB 4.11Å; F39-L43 PolarHBondContact O-N 3.45Å; A40-L43 CarbonylContact O-C 3.6Å; A40-L43 WeakPolarHBondContact O-CA 3.44Å; A40-L43 WeakPolarHBondContact O-CB 3.5Å; A40-L43 PolarHBondContact O-N 3.15Å; A40-L43 VanDerWaalsContact O-N 3.1Å; L43-V45 VanDerWaalsContact C-N 3.33Å; L43-V45 PolarHBondContact O-N 2.88Å; L43-K46 PolarHBondContact O-N 2.8Å; L43-K46 VanDerWaalsContact O-N 3.12Å; L43-L47 HydrophobicContact CD1-CD1 4.46Å; L43-L47 HydrophobicContact CD1-CG 4.36Å; L43-L47 HydrophobicContact CG-CD1 4.05Å; L43-L47 HydrophobicContact CG-CG 4.39Å; L43-L47 WeakPolarHBondContact O-CG 3.38Å; L43-L47 PolarHBondContact O-N 3.05Å
44F94.8Very high88.9Confident3 Ų364.3 Ų64.31%0.01332%0.315CS..Hα-helixtrans-62-41.2178.9-57.2-30.5000111.9L6 I9 L13 A40 R41 K46 L47 E48 L53 L58L6-F44 HydrophobicContact CB-CD2 3.98Å; L6-F44 HydrophobicContact CB-CE2 4.42Å; L6-F44 HydrophobicContact CD2-CD2 3.9Å; L6-F44 HydrophobicContact CD2-CE2 4.23Å; L6-F44 HydrophobicContact CD2-CG 4.17Å; L6-F44 HydrophobicContact CG-CD2 4.4Å; I9-F44 HydrophobicContact CB-CE2 4.38Å; I9-F44 HydrophobicContact CG2-CE2 3.91Å; I9-F44 HydrophobicContact CG2-CZ 3.61Å; L13-F44 HydrophobicContact CD1-CZ 4.4Å; A40-F44 HydrophobicContact CB-CE1 4.4Å; A40-F44 HydrophobicContact CB-CE2 3.81Å; A40-F44 HydrophobicContact CB-CZ 3.69Å; A40-F44 WeakPolarHBondContact O-CD1 3.44Å; A40-F44 VanDerWaalsContact O-CD2 3.27Å; A40-F44 WeakPolarHBondContact O-CD2 3.21Å; A40-F44 WeakPolarHBondContact O-CG 3.26Å; A40-F44 PolarHBondContact O-N 2.82Å; R41-F44 PolarHBondContact O-N 2.84Å; F44-K46 VanDerWaalsContact C-N 3.32Å; F44-K46 PolarHBondContact O-N 3.46Å; F44-L47 HydrophobicContact CD1-CD1 4.44Å; F44-L47 PolarHBondContact O-N 2.69Å; F44-E48 WeakPolarHBondContact O-CB 3.36Å; F44-E48 PolarHBondContact O-N 3.16Å; F44-L53 HydrophobicContact CB-CD1 3.98Å; F44-L53 HydrophobicContact CB-CD2 4.29Å; F44-L53 HydrophobicContact CD1-CD1 4.1Å; F44-L53 HydrophobicContact CG-CD1 4.29Å; F44-L58 HydrophobicContact CD1-CD2 4.02Å; F44-L58 HydrophobicContact CE1-CD2 3.74Å
45V92.8Very high88.6Confident60 Ų6065.2 Ų65.236%0.36432%0.322SS..Hα-helixtrans-59.5-43.8173.6172.20000110.8R41 D42 L43 E48 E49R41-V45 WeakPolarHBondContact O-CG2 3.27Å; R41-V45 PolarHBondContact O-N 3.35Å; D42-V45 PolarHBondContact O-N 2.98Å; L43-V45 VanDerWaalsContact C-N 3.33Å; L43-V45 PolarHBondContact O-N 2.88Å; V45-E48 WeakPolarHBondContact O-CB 3.48Å; V45-E48 PolarHBondContact O-N 2.54Å; V45-E49 WeakPolarHBondContact O-CG 3.43Å; V45-E49 PolarHBondContact O-N 3.01Å
46K92Very high88.2Confident51 Ų5160.1 Ų60.122%0.22230%0.3CS..Hα-helixtrans-67-38.1177.5-66.2-45.9-176.7-167.10113.7I29 I37 D42 L43 F44 E48 E49 K50I29-K46 HydrophobicContact CD1-CB 3.65Å; I29-K46 HydrophobicContact CG1-CB 4.34Å; I29-K46 HydrophobicContact CG2-CB 4.37Å; I37-K46 HydrophobicContact CD1-CG 4.45Å; D42-K46 WeakPolarHBondContact O-CG 3.45Å; D42-K46 PolarHBondContact O-N 2.6Å; D42-K46 VanDerWaalsContact O-N 3.13Å; L43-K46 PolarHBondContact O-N 2.8Å; L43-K46 VanDerWaalsContact O-N 3.12Å; F44-K46 VanDerWaalsContact C-N 3.32Å; F44-K46 PolarHBondContact O-N 3.46Å; K46-E48 VanDerWaalsContact C-N 3.29Å; K46-E48 PolarHBondContact O-N 2.81Å; K46-E49 WeakPolarHBondContact CD-OE2 3.46Å; K46-E49 VanDerWaalsContact NZ-CD 3.25Å; K46-E49 IonicContact NZ-OE1 2.74Å; K46-E49 PolarHBondContact NZ-OE1 3.05Å; K46-E49 IonicContact NZ-OE2 3.91Å; K46-E49 PolarHBondContact NZ-OE2 2.99Å; K46-K50 WeakPolarHBondContact O-CG 3.41Å; K46-K50 PolarHBondContact O-N 3.36Å
47L89.2Confident87.9Confident0 Ų052.9 Ų52.90%027%0.266CS..Hα-helixtrans-64.8-36173.1-70.7171.5000111.4C25 V28 I29 L43 F44 K50 G51 F52 L53 F57C25-L47 HydrophobicContact CB-CD2 4.47Å; V28-L47 HydrophobicContact CG1-CD2 4.1Å; I29-L47 HydrophobicContact CD1-CD2 3.62Å; I29-L47 HydrophobicContact CD1-CG 3.8Å; I29-L47 HydrophobicContact CG1-CD2 4.17Å; L43-L47 HydrophobicContact CD1-CD1 4.46Å; L43-L47 HydrophobicContact CD1-CG 4.36Å; L43-L47 HydrophobicContact CG-CD1 4.05Å; L43-L47 HydrophobicContact CG-CG 4.39Å; L43-L47 WeakPolarHBondContact O-CG 3.38Å; L43-L47 PolarHBondContact O-N 3.05Å; F44-L47 HydrophobicContact CD1-CD1 4.44Å; F44-L47 PolarHBondContact O-N 2.69Å; L47-K50 PolarHBondContact O-N 3.05Å; L47-G51 PolarHBondContact O-N 2.91Å; L47-G51 VanDerWaalsContact O-N 3.11Å; L47-F52 HydrophobicContact CD2-CB 4.08Å; L47-F52 PolarHBondContact O-N 2.84Å; L47-L53 HydrophobicContact CB-CB 3.93Å; L47-L53 HydrophobicContact CB-CD1 4.24Å; L47-L53 HydrophobicContact CD1-CD1 4.48Å; L47-L53 PolarHBondContact O-N 3.35Å; L47-F57 HydrophobicContact CD1-CD1 4.06Å; L47-F57 HydrophobicContact CD1-CE1 3.7Å; L47-F57 HydrophobicContact CD2-CD1 4.32Å; L47-F57 HydrophobicContact CD2-CE1 3.52Å; L47-F57 HydrophobicContact CD2-CZ 4.18Å; L47-F57 HydrophobicContact CG-CE1 4.23Å
48E87.6Confident87.8Confident73 Ų7351.8 Ų51.834%0.34126%0.261SS..Hα-helixtrans-69.1-45.9177.3-166.2173.6-136.800111.7R3 F44 V45 K46 K50 G51 L53R3-E48 IonicContact CZ-OE1 3.2Å; R3-E48 IonicContact CZ-OE2 2.82Å; R3-E48 IonicContact NH1-OE1 2.88Å; R3-E48 IonicContact NH1-OE2 2.86Å; R3-E48 PolarHBondContact NH1-OE2 2.92Å; R3-E48 VanDerWaalsContact NH2-CD 3.3Å; R3-E48 IonicContact NH2-OE1 2.81Å; R3-E48 PolarHBondContact NH2-OE1 3.45Å; R3-E48 IonicContact NH2-OE2 3.35Å; R3-E48 PolarHBondContact NH2-OE2 3.37Å; F44-E48 WeakPolarHBondContact O-CB 3.36Å; F44-E48 PolarHBondContact O-N 3.16Å; V45-E48 WeakPolarHBondContact O-CB 3.48Å; V45-E48 PolarHBondContact O-N 2.54Å; K46-E48 VanDerWaalsContact C-N 3.29Å; K46-E48 PolarHBondContact O-N 2.81Å; E48-K50 PolarHBondContact O-N 2.74Å; E48-K50 VanDerWaalsContact O-N 3.16Å; E48-G51 PolarHBondContact O-N 2.74Å; E48-L53 HydrophobicContact CB-CB 3.92Å; E48-L53 HydrophobicContact CB-CD2 3.76Å; E48-L53 HydrophobicContact CB-CG 4.48Å; E48-L53 HydrophobicContact CG-CB 4.5Å; E48-L53 HydrophobicContact CG-CD2 4.16Å
49E87Confident87.4Confident113 Ų11344.5 Ų44.553%0.52823%0.23SC..Hα-helixtrans-55-32.3173.5-74.6174.3-169.400112.2V45 K46V45-E49 WeakPolarHBondContact O-CG 3.43Å; V45-E49 PolarHBondContact O-N 3.01Å; K46-E49 WeakPolarHBondContact CD-OE2 3.46Å; K46-E49 VanDerWaalsContact NZ-CD 3.25Å; K46-E49 IonicContact NZ-OE1 2.74Å; K46-E49 PolarHBondContact NZ-OE1 3.05Å; K46-E49 IonicContact NZ-OE2 3.91Å; K46-E49 PolarHBondContact NZ-OE2 2.99Å
50K80.8Confident86.9Confident102 Ų10240.5 Ų40.544%0.44321%0.213SC..THydrogen-bonded Turntrans-90.1-5.2178.6-64.6-65.5-177.8-176.80114.1K46 L47 E48 F52K46-K50 WeakPolarHBondContact O-CG 3.41Å; K46-K50 PolarHBondContact O-N 3.36Å; L47-K50 PolarHBondContact O-N 3.05Å; E48-K50 PolarHBondContact O-N 2.74Å; E48-K50 VanDerWaalsContact O-N 3.16Å; K50-F52 VanDerWaalsContact C-N 3.34Å; K50-F52 HydrophobicContact CB-CD2 3.74Å; K50-F52 HydrophobicContact CB-CE2 4.32Å; K50-F52 WeakPolarHBondContact O-CD2 3.1Å
51G79.9Confident86.7Confident65 Ų6540.5 Ų40.567%0.6721%0.213SC*.THydrogen-bonded Turntrans75.616.3-177.600000115L47 E48L47-G51 PolarHBondContact O-N 2.91Å; L47-G51 VanDerWaalsContact O-N 3.11Å; E48-G51 PolarHBondContact O-N 2.74Å
52F79.9Confident86.5Confident79 Ų7935.4 Ų35.435%0.34619%0.193SC..  trans-99.2-10.9179.9-74.9-95.9000113.7V28 L47 K50 N54 F57V28-F52 HydrophobicContact CG1-CB 3.9Å; V28-F52 HydrophobicContact CG1-CD1 3.77Å; V28-F52 HydrophobicContact CG1-CD2 3.26Å; V28-F52 HydrophobicContact CG1-CE1 4.06Å; V28-F52 HydrophobicContact CG1-CE2 3.59Å; V28-F52 HydrophobicContact CG1-CG 3.35Å; V28-F52 HydrophobicContact CG1-CZ 3.98Å; V28-F52 HydrophobicContact CG2-CD1 4.06Å; V28-F52 HydrophobicContact CG2-CE1 3.98Å; V28-F52 HydrophobicContact CG2-CG 4.48Å; V28-F52 HydrophobicContact CG2-CZ 4.36Å; L47-F52 HydrophobicContact CD2-CB 4.08Å; L47-F52 PolarHBondContact O-N 2.84Å; K50-F52 VanDerWaalsContact C-N 3.34Å; K50-F52 HydrophobicContact CB-CD2 3.74Å; K50-F52 HydrophobicContact CB-CE2 4.32Å; K50-F52 WeakPolarHBondContact O-CD2 3.1Å; F52-N54 PolarHBondContact O-N 3.28Å; F52-N54 PolarHBondContact O-ND2 2.89Å; F52-F57 WeakPolarHBondContact O-CB 3.31Å; F52-F57 WeakPolarHBondContact O-CG 3.36Å
53L85.1Confident86.1Confident21 Ų2137.1 Ų37.111%0.1120%0.195CC..  trans-74.594.9180-172.470.3000111.9M1 L6 F44 L47 E48 L58M1-L53 HydrophobicContact CE-CD1 3.63Å; M1-L53 HydrophobicContact CE-CG 3.63Å; L6-L53 HydrophobicContact CD1-CD2 3.87Å; L6-L53 HydrophobicContact CD2-CD1 4.49Å; F44-L53 HydrophobicContact CB-CD1 3.98Å; F44-L53 HydrophobicContact CB-CD2 4.29Å; F44-L53 HydrophobicContact CD1-CD1 4.1Å; F44-L53 HydrophobicContact CG-CD1 4.29Å; L47-L53 HydrophobicContact CB-CB 3.93Å; L47-L53 HydrophobicContact CB-CD1 4.24Å; L47-L53 HydrophobicContact CD1-CD1 4.48Å; L47-L53 PolarHBondContact O-N 3.35Å; E48-L53 HydrophobicContact CB-CB 3.92Å; E48-L53 HydrophobicContact CB-CD2 3.76Å; E48-L53 HydrophobicContact CB-CG 4.48Å; E48-L53 HydrophobicContact CG-CB 4.5Å; E48-L53 HydrophobicContact CG-CD2 4.16Å; L53-L58 HydrophobicContact CD1-CD1 4.17Å; L53-L58 HydrophobicContact CD1-CD2 4.14Å; L53-L58 HydrophobicContact CD1-CG 4.27Å
54N82.4Confident85.7Confident43 Ų4338.4 Ų38.423%0.2320%0.203CC..  trans-140.8161.6172.658.760.7000110.7M1 F52 T56 F57 L58 Y90M1-N54 WeakPolarHBondContact CE-O 3.43Å; F52-N54 PolarHBondContact O-N 3.28Å; F52-N54 PolarHBondContact O-ND2 2.89Å; N54-T56 PolarHBondContact O-N 2.96Å; N54-T56 PolarHBondContact OD1-N 2.67Å; N54-T56 PolarHBondContact OD1-OG1 2.88Å; N54-F57 PolarHBondContact O-N 3.39Å; N54-F57 WeakPolarHBondContact OD1-CB 3.37Å; N54-F57 PolarHBondContact OD1-N 3.37Å; N54-L58 PolarHBondContact O-N 2.85Å; N54-L58 VanDerWaalsContact O-N 3.12Å; N54-Y90 PolarHBondContact OD1-OH 2.85Å
55S80.7Confident85.4Confident33 Ų3339 Ų3923%0.23121%0.207CC..Hα-helixtrans-60.4-34.9-174.545.90000112.6A59S55-A59 WeakPolarHBondContact O-CB 3.32Å; S55-A59 PolarHBondContact O-N 2.78Å
56T77.2Confident85.2Confident21 Ų2144.5 Ų44.513%0.12922%0.222CC..Hα-helixtrans-72.9-39.3-178.746.70000112.1N54 A59 E60 E82 Y90N54-T56 PolarHBondContact O-N 2.96Å; N54-T56 PolarHBondContact OD1-N 2.67Å; N54-T56 PolarHBondContact OD1-OG1 2.88Å; T56-A59 PolarHBondContact O-N 3.04Å; T56-E60 PolarHBondContact O-N 3.04Å; T56-E82 HydrophobicContact CG2-CG 4.43Å; T56-E82 WeakPolarHBondContact CG2-OE1 3.45Å; T56-Y90 WeakPolarHBondContact OG1-CE2 3.31Å; T56-Y90 PolarHBondContact OG1-OH 3.34Å
57F82.4Confident85.1Confident0 Ų043.5 Ų43.50%022%0.216CC..Hα-helixtrans-61.7-49.3171.6-172.9-111.8000111.5L47 F52 N54 A59 E60 L61 Y90 L91L47-F57 HydrophobicContact CD1-CD1 4.06Å; L47-F57 HydrophobicContact CD1-CE1 3.7Å; L47-F57 HydrophobicContact CD2-CD1 4.32Å; L47-F57 HydrophobicContact CD2-CE1 3.52Å; L47-F57 HydrophobicContact CD2-CZ 4.18Å; L47-F57 HydrophobicContact CG-CE1 4.23Å; F52-F57 WeakPolarHBondContact O-CB 3.31Å; F52-F57 WeakPolarHBondContact O-CG 3.36Å; N54-F57 PolarHBondContact O-N 3.39Å; N54-F57 WeakPolarHBondContact OD1-CB 3.37Å; N54-F57 PolarHBondContact OD1-N 3.37Å; F57-A59 VanDerWaalsContact C-N 3.31Å; F57-A59 PolarHBondContact O-N 2.94Å; F57-E60 PolarHBondContact O-N 3.44Å; F57-L61 HydrophobicContact CD1-CD1 3.81Å; F57-L61 HydrophobicContact CE1-CD1 3.55Å; F57-L61 HydrophobicContact CE1-CG 4.23Å; F57-L61 HydrophobicContact CZ-CD1 4.22Å; F57-L61 HydrophobicContact CZ-CG 4.48Å; F57-L61 PolarHBondContact O-N 2.91Å; F57-Y90 HydrophobicContact CB-CD1 4.49Å; F57-Y90 HydrophobicContact CB-CD2 4.09Å; F57-Y90 HydrophobicContact CB-CE2 4.27Å; F57-Y90 HydrophobicContact CB-CG 4.26Å; F57-Y90 AromaticContact CD2-CD1 3.92Å; F57-Y90 HydrophobicContact CD2-CD1 3.92Å; F57-Y90 AromaticContact CD2-CD2 3.91Å; F57-Y90 HydrophobicContact CD2-CD2 3.91Å; F57-Y90 AromaticContact CD2-CG 3.44Å; F57-Y90 HydrophobicContact CD2-CG 3.44Å; F57-Y90 VanDerWaalsContact CD2-CG 3.44Å; F57-Y90 VanDerWaalsContact CE2-CB 3.4Å; F57-Y90 HydrophobicContact CE2-CG 4.19Å; F57-Y90 HydrophobicContact CG-CG 4.35Å; F57-L91 HydrophobicContact CE2-CD2 4.05Å; F57-L91 HydrophobicContact CZ-CD2 4.13Å
58L87.7Confident84.9Confident0 Ų046.2 Ų46.20%024%0.239CC..Hα-helixtrans-64.1-38.6176.9-67.6-170.9000111.7M1 L6 F44 L53 N54 E60 L61 F62 L74M1-L58 HydrophobicContact CE-CD1 3.23Å; M1-L58 HydrophobicContact CE-CG 3.69Å; M1-L58 HydrophobicContact SD-CD1 3.67Å; L6-L58 HydrophobicContact CD2-CD1 3.69Å; F44-L58 HydrophobicContact CD1-CD2 4.02Å; F44-L58 HydrophobicContact CE1-CD2 3.74Å; L53-L58 HydrophobicContact CD1-CD1 4.17Å; L53-L58 HydrophobicContact CD1-CD2 4.14Å; L53-L58 HydrophobicContact CD1-CG 4.27Å; N54-L58 PolarHBondContact O-N 2.85Å; N54-L58 VanDerWaalsContact O-N 3.12Å; L58-E60 VanDerWaalsContact C-N 3.3Å; L58-E60 PolarHBondContact O-N 2.76Å; L58-L61 HydrophobicContact CD2-CD1 4.01Å; L58-L61 WeakPolarHBondContact O-CB 3.45Å; L58-L61 PolarHBondContact O-N 2.86Å; L58-F62 HydrophobicContact CB-CE2 3.99Å; L58-F62 HydrophobicContact CB-CZ 4.34Å; L58-F62 VanDerWaalsContact O-CD2 3.24Å; L58-F62 WeakPolarHBondContact O-CD2 3.38Å; L58-F62 VanDerWaalsContact O-CG 3.22Å; L58-F62 WeakPolarHBondContact O-CG 3.43Å; L58-F62 PolarHBondContact O-N 3.41Å; L58-L74 HydrophobicContact CB-CD1 3.68Å; L58-L74 HydrophobicContact CB-CD2 4.33Å; L58-L74 HydrophobicContact CD1-CD2 4.13Å
59A84.4Confident84.9Confident7 Ų746.1 Ų46.16%0.05824%0.241CC..Hα-helixtrans-62.7-37.4176.300000112S55 T56 F57 R63 L71 L74S55-A59 WeakPolarHBondContact O-CB 3.32Å; S55-A59 PolarHBondContact O-N 2.78Å; T56-A59 PolarHBondContact O-N 3.04Å; F57-A59 VanDerWaalsContact C-N 3.31Å; F57-A59 PolarHBondContact O-N 2.94Å; A59-R63 WeakPolarHBondContact O-CB 3.42Å; A59-R63 WeakPolarHBondContact O-CG 3.38Å; A59-R63 PolarHBondContact O-N 2.86Å; A59-L71 HydrophobicContact CB-CD1 3.56Å; A59-L74 HydrophobicContact CB-CD1 4.18Å
60E84.1Confident85Confident13 Ų1340.8 Ų40.86%0.06122%0.216CC..Hα-helixtrans-69.4-42.2173.9-172.4-169.8-169.600112.8T56 F57 L58 F62 R63 T64 A89 Y90 L91T56-E60 PolarHBondContact O-N 3.04Å; F57-E60 PolarHBondContact O-N 3.44Å; L58-E60 VanDerWaalsContact C-N 3.3Å; L58-E60 PolarHBondContact O-N 2.76Å; E60-F62 VanDerWaalsContact C-N 3.33Å; E60-F62 PolarHBondContact O-N 3.13Å; E60-R63 PolarHBondContact O-N 2.97Å; E60-T64 WeakPolarHBondContact O-CB 3.47Å; E60-T64 PolarHBondContact O-N 3.44Å; E60-T64 PolarHBondContact O-OG1 2.81Å; E60-A89 WeakPolarHBondContact OE1-CA 3.48Å; E60-A89 WeakPolarHBondContact OE1-CB 3.34Å; E60-A89 WeakPolarHBondContact OE2-CA 3.27Å; E60-Y90 VanDerWaalsContact CD-N 3.3Å; E60-Y90 PolarHBondContact OE1-N 2.76Å; E60-Y90 WeakPolarHBondContact OE2-CA 3.47Å; E60-Y90 VanDerWaalsContact OE2-CB 3.29Å; E60-Y90 WeakPolarHBondContact OE2-CB 3.28Å; E60-Y90 WeakPolarHBondContact OE2-CD2 3.06Å; E60-Y90 PolarHBondContact OE2-N 2.61Å; E60-L91 HydrophobicContact CG-CD1 4.06Å; E60-L91 HydrophobicContact CG-CG 4.25Å; E60-L91 WeakPolarHBondContact OE1-CB 3.3Å; E60-L91 PolarHBondContact OE1-N 2.89Å; E60-L91 VanDerWaalsContact OE1-N 3.07Å; E60-L91 PolarHBondContact OE2-N 3.34Å; E60-L91 VanDerWaalsContact OE2-N 3.14Å
61L89.3Confident85.2Confident0 Ų037 Ų370%020%0.201CC..Hα-helixtrans-55-50.1172.6-78.5170.4000110.7L21 L24 F57 L58 R63 T64 T65 L91L21-L61 HydrophobicContact CD2-CB 3.8Å; L21-L61 HydrophobicContact CD2-CD1 4.39Å; L21-L61 HydrophobicContact CD2-CD2 3.98Å; L21-L61 HydrophobicContact CD2-CG 4.29Å; L24-L61 HydrophobicContact CB-CD2 3.71Å; L24-L61 HydrophobicContact CD1-CD2 3.98Å; F57-L61 HydrophobicContact CD1-CD1 3.81Å; F57-L61 HydrophobicContact CE1-CD1 3.55Å; F57-L61 HydrophobicContact CE1-CG 4.23Å; F57-L61 HydrophobicContact CZ-CD1 4.22Å; F57-L61 HydrophobicContact CZ-CG 4.48Å; F57-L61 PolarHBondContact O-N 2.91Å; L58-L61 HydrophobicContact CD2-CD1 4.01Å; L58-L61 WeakPolarHBondContact O-CB 3.45Å; L58-L61 PolarHBondContact O-N 2.86Å; L61-R63 PolarHBondContact O-N 2.83Å; L61-T64 WeakPolarHBondContact O-CB 3.44Å; L61-T64 PolarHBondContact O-N 2.81Å; L61-T64 VanDerWaalsContact O-N 3.13Å; L61-T65 PolarHBondContact O-N 2.9Å; L61-T65 PolarHBondContact O-OG1 2.97Å; L61-L91 HydrophobicContact CD2-CD1 3.98Å; L61-L91 HydrophobicContact CD2-CD2 3.85Å; L61-L91 HydrophobicContact CD2-CG 4.44Å; L61-L91 HydrophobicContact CG-CD1 4.5Å
62F90.8Very high85.3Confident0 Ų038.4 Ų38.40%019%0.193CC..Hα-helixtrans-71.8-29.8-178.7-57.7-29.1000113.8I9 L13 L21 L58 E60 T64 R66 R67 L70 L74I9-F62 HydrophobicContact CD1-CE2 4.17Å; I9-F62 HydrophobicContact CG2-CE1 4.36Å; I9-F62 HydrophobicContact CG2-CE2 4.1Å; I9-F62 HydrophobicContact CG2-CZ 3.51Å; L13-F62 HydrophobicContact CD1-CE1 4.42Å; L21-F62 HydrophobicContact CD1-CE1 4.21Å; L21-F62 HydrophobicContact CD2-CD1 4.44Å; L21-F62 HydrophobicContact CD2-CE1 4.37Å; L58-F62 HydrophobicContact CB-CE2 3.99Å; L58-F62 HydrophobicContact CB-CZ 4.34Å; L58-F62 VanDerWaalsContact O-CD2 3.24Å; L58-F62 WeakPolarHBondContact O-CD2 3.38Å; L58-F62 VanDerWaalsContact O-CG 3.22Å; L58-F62 WeakPolarHBondContact O-CG 3.43Å; L58-F62 PolarHBondContact O-N 3.41Å; E60-F62 VanDerWaalsContact C-N 3.33Å; E60-F62 PolarHBondContact O-N 3.13Å; F62-T64 VanDerWaalsContact C-N 3.33Å; F62-R66 CarbonylContact O-C 3.53Å; F62-R66 WeakPolarHBondContact O-CA 3.5Å; F62-R66 PolarHBondContact O-N 3.32Å; F62-R67 HydrophobicContact CB-CB 4.23Å; F62-R67 PolarHBondContact O-N 3.13Å; F62-L70 HydrophobicContact CB-CB 4.43Å; F62-L70 HydrophobicContact CD1-CB 4.33Å; F62-L70 HydrophobicContact CD1-CD1 3.99Å; F62-L70 HydrophobicContact CD2-CB 3.59Å; F62-L70 HydrophobicContact CE1-CD1 3.89Å; F62-L70 HydrophobicContact CE2-CB 3.87Å; F62-L70 HydrophobicContact CE2-CD1 4.46Å; F62-L70 HydrophobicContact CG-CB 3.87Å; F62-L70 HydrophobicContact CG-CD1 4.38Å; F62-L70 HydrophobicContact CZ-CB 4.39Å; F62-L70 HydrophobicContact CZ-CD1 4.16Å; F62-L74 HydrophobicContact CD2-CD1 3.47Å; F62-L74 VanDerWaalsContact CD2-CD1 3.47Å; F62-L74 HydrophobicContact CD2-CG 4.26Å; F62-L74 HydrophobicContact CE2-CD1 3.56Å; F62-L74 HydrophobicContact CE2-CG 4.08Å
63R86.1Confident85.6Confident95 Ų9536.3 Ų36.336%0.35818%0.184SC..Hα-helixtrans-65-40.3168.2-76.7176.1-150.2121.40.3111.3A59 E60 L61 R66 L71A59-R63 WeakPolarHBondContact O-CB 3.42Å; A59-R63 WeakPolarHBondContact O-CG 3.38Å; A59-R63 PolarHBondContact O-N 2.86Å; E60-R63 PolarHBondContact O-N 2.97Å; L61-R63 PolarHBondContact O-N 2.83Å; R63-R66 PolarHBondContact O-N 3.09Å; R63-L71 HydrophobicContact CG-CD1 4.07Å; R63-L71 HydrophobicContact CG-CD2 4.01Å
64T85.8Confident85.3Confident27 Ų2735.7 Ų35.717%0.16618%0.181CC..Hα-helixtrans-67.5-45.8-179.6-56.20000110.9L24 E60 L61 F62 R66 L91 L96 Y99L24-T64 HydrophobicContact CD1-CG2 3.71Å; L24-T64 HydrophobicContact CD2-CG2 4.01Å; E60-T64 WeakPolarHBondContact O-CB 3.47Å; E60-T64 PolarHBondContact O-N 3.44Å; E60-T64 PolarHBondContact O-OG1 2.81Å; L61-T64 WeakPolarHBondContact O-CB 3.44Å; L61-T64 PolarHBondContact O-N 2.81Å; L61-T64 VanDerWaalsContact O-N 3.13Å; F62-T64 VanDerWaalsContact C-N 3.33Å; T64-R66 PolarHBondContact O-N 2.88Å; T64-L91 HydrophobicContact CG2-CD1 4.43Å; T64-L96 HydrophobicContact CG2-CD2 3.71Å; T64-Y99 HydrophobicContact CG2-CD1 3.71Å; T64-Y99 HydrophobicContact CG2-CE1 4.09Å; T64-Y99 HydrophobicContact CG2-CG 4.1Å; T64-Y99 VanDerWaalsContact O-CE1 3.24Å; T64-Y99 WeakPolarHBondContact O-CE1 3.38Å
65T89.3Confident84.8Confident15 Ų1538.8 Ų38.89%0.09219%0.194CC..THydrogen-bonded Turntrans-81.26.4176650000114E20 L21 L24 L61 R67 Y99E20-T65 HydrophobicContact CB-CG2 4.48Å; L21-T65 HydrophobicContact CD2-CG2 3.83Å; L24-T65 HydrophobicContact CD1-CG2 3.88Å; L61-T65 PolarHBondContact O-N 2.9Å; L61-T65 PolarHBondContact O-OG1 2.97Å; T65-R67 PolarHBondContact O-N 3.46Å; T65-R67 VanDerWaalsContact O-N 3.17Å; T65-Y99 WeakPolarHBondContact CA-OH 3.17Å; T65-Y99 HydrophobicContact CG2-CE2 4.4Å
66R86.6Confident84.2Confident177 Ų17742 Ų4267%0.66822%0.216SC*.THydrogen-bonded Turntrans56.926.3178.8-54.2-176.1-178.7178.47.5115.2F62 R63 T64 A68 E103F62-R66 CarbonylContact O-C 3.53Å; F62-R66 WeakPolarHBondContact O-CA 3.5Å; F62-R66 PolarHBondContact O-N 3.32Å; R63-R66 PolarHBondContact O-N 3.09Å; T64-R66 PolarHBondContact O-N 2.88Å; R66-A68 PolarHBondContact O-N 3.01Å; R66-A68 VanDerWaalsContact O-N 3.1Å; R66-E103 IonicContact CZ-OE2 3Å; R66-E103 IonicContact NE-OE2 3.38Å; R66-E103 IonicContact NH1-OE2 3.64Å; R66-E103 IonicContact NH2-OE2 2.86Å
67R90.1Very high83.4Confident29 Ų2944.4 Ų44.411%0.10923%0.229CC..  trans-83.972.8173.7-73.2-63.4-61.1-85.9-0.2112.3D12 E17 F62 T65 D69 L70 L71D12-R67 VanDerWaalsContact O-CZ 3.28Å; D12-R67 PolarHBondContact O-NH1 3.13Å; D12-R67 PolarHBondContact O-NH2 2.83Å; E17-R67 VanDerWaalsContact OE1-CD 3.27Å; E17-R67 WeakPolarHBondContact OE1-CD 3.49Å; E17-R67 IonicContact OE1-CZ 2.96Å; E17-R67 IonicContact OE1-NE 3.18Å; E17-R67 IonicContact OE1-NH1 3.57Å; E17-R67 PolarHBondContact OE1-NH1 3.37Å; E17-R67 IonicContact OE2-NH1 2.8Å; E17-R67 PolarHBondContact OE2-NH1 3.02Å; F62-R67 HydrophobicContact CB-CB 4.23Å; F62-R67 PolarHBondContact O-N 3.13Å; T65-R67 PolarHBondContact O-N 3.46Å; T65-R67 VanDerWaalsContact O-N 3.17Å; R67-D69 WeakPolarHBondContact CA-OD1 3.47Å; R67-D69 IonicContact CZ-OD1 2.71Å; R67-D69 IonicContact CZ-OD2 3.96Å; R67-D69 IonicContact NE-OD1 3.23Å; R67-D69 PolarHBondContact NE-OD1 2.82Å; R67-D69 IonicContact NE-OD2 2.96Å; R67-D69 PolarHBondContact NE-OD2 3.25Å; R67-D69 IonicContact NH2-OD1 3.83Å; R67-D69 IonicContact NH2-OD2 3.93Å; R67-D69 PolarHBondContact NH2-OD2 2.83Å; R67-D69 PolarHBondContact O-N 2.81Å; R67-L70 HydrophobicContact CB-CB 4.18Å; R67-L70 HydrophobicContact CB-CD1 3.92Å; R67-L70 HydrophobicContact CB-CG 4.08Å; R67-L70 HydrophobicContact CG-CD1 4.17Å; R67-L70 PolarHBondContact O-N 3.42Å; R67-L71 PolarHBondContact O-N 2.84Å; R67-L71 VanDerWaalsContact O-N 3.08Å
68A85.1Confident82Confident58 Ų5846.8 Ų46.848%0.47925%0.245SC..Hα-helixtrans-63-29.5-179.300000113.4R66 L71 N72R66-A68 PolarHBondContact O-N 3.01Å; R66-A68 VanDerWaalsContact O-N 3.1Å; A68-L71 WeakPolarHBondContact O-CB 3.3Å; A68-L71 PolarHBondContact O-N 2.8Å; A68-N72 WeakPolarHBondContact O-CB 3.4Å; A68-N72 PolarHBondContact O-N 2.93Å; A68-N72 PolarHBondContact O-ND2 3.1Å; A68-N72 VanDerWaalsContact O-ND2 3.08Å
69D87.8Confident80.2Confident71 Ų7158.6 Ų58.638%0.3829%0.29SS..Hα-helixtrans-62-48.6173.559.3-47.9000111.9R67 L71 N72 M73R67-D69 WeakPolarHBondContact CA-OD1 3.47Å; R67-D69 IonicContact CZ-OD1 2.71Å; R67-D69 IonicContact CZ-OD2 3.96Å; R67-D69 IonicContact NE-OD1 3.23Å; R67-D69 PolarHBondContact NE-OD1 2.82Å; R67-D69 IonicContact NE-OD2 2.96Å; R67-D69 PolarHBondContact NE-OD2 3.25Å; R67-D69 IonicContact NH2-OD1 3.83Å; R67-D69 IonicContact NH2-OD2 3.93Å; R67-D69 PolarHBondContact NH2-OD2 2.83Å; R67-D69 PolarHBondContact O-N 2.81Å; D69-L71 VanDerWaalsContact C-N 3.33Å; D69-L71 PolarHBondContact O-N 3.38Å; D69-N72 PolarHBondContact O-N 2.94Å; D69-M73 WeakPolarHBondContact O-CG 3.17Å; D69-M73 PolarHBondContact O-N 2.76Å
70L89.8Confident78.2Confident0 Ų065.9 Ų65.90%032%0.322CS..Hα-helixtrans-67.7-34.9176.9-60.4-177.2000111.9I9 D12 L13 F62 R67 M73 L74I9-L70 HydrophobicContact CG1-CD2 4.45Å; I9-L70 HydrophobicContact CG2-CD1 4.38Å; D12-L70 HydrophobicContact CB-CD2 3.78Å; L13-L70 HydrophobicContact CD1-CD1 4.26Å; L13-L70 HydrophobicContact CD2-CD1 3.7Å; L13-L70 HydrophobicContact CG-CD1 3.86Å; F62-L70 HydrophobicContact CB-CB 4.43Å; F62-L70 HydrophobicContact CD1-CB 4.33Å; F62-L70 HydrophobicContact CD1-CD1 3.99Å; F62-L70 HydrophobicContact CD2-CB 3.59Å; F62-L70 HydrophobicContact CE1-CD1 3.89Å; F62-L70 HydrophobicContact CE2-CB 3.87Å; F62-L70 HydrophobicContact CE2-CD1 4.46Å; F62-L70 HydrophobicContact CG-CB 3.87Å; F62-L70 HydrophobicContact CG-CD1 4.38Å; F62-L70 HydrophobicContact CZ-CB 4.39Å; F62-L70 HydrophobicContact CZ-CD1 4.16Å; R67-L70 HydrophobicContact CB-CB 4.18Å; R67-L70 HydrophobicContact CB-CD1 3.92Å; R67-L70 HydrophobicContact CB-CG 4.08Å; R67-L70 HydrophobicContact CG-CD1 4.17Å; R67-L70 PolarHBondContact O-N 3.42Å; L70-M73 HydrophobicContact CD2-SD 3.98Å; L70-M73 WeakPolarHBondContact O-CB 3.49Å; L70-M73 PolarHBondContact O-N 2.71Å; L70-L74 WeakPolarHBondContact O-CG 3.47Å; L70-L74 PolarHBondContact O-N 3.44Å
71L85.1Confident76.3Confident24 Ų2475.8 Ų75.813%0.12636%0.359CS..Hα-helixtrans-60.3-48.4172.5-173.674.5000111.1A59 R63 R67 A68 D69 M73 L74 E75A59-L71 HydrophobicContact CB-CD1 3.56Å; R63-L71 HydrophobicContact CG-CD1 4.07Å; R63-L71 HydrophobicContact CG-CD2 4.01Å; R67-L71 PolarHBondContact O-N 2.84Å; R67-L71 VanDerWaalsContact O-N 3.08Å; A68-L71 WeakPolarHBondContact O-CB 3.3Å; A68-L71 PolarHBondContact O-N 2.8Å; D69-L71 VanDerWaalsContact C-N 3.33Å; D69-L71 PolarHBondContact O-N 3.38Å; L71-M73 VanDerWaalsContact C-N 3.28Å; L71-M73 PolarHBondContact O-N 2.79Å; L71-L74 WeakPolarHBondContact O-CB 3.41Å; L71-L74 PolarHBondContact O-N 2.81Å; L71-E75 WeakPolarHBondContact O-CG 3.39Å; L71-E75 PolarHBondContact O-N 2.87Å
72N82.7Confident74.1Confident94 Ų9479.6 Ų79.650%0.50338%0.377SS..Hα-helixtrans-62.4-36.6177.2-68.6-29.8000111.6A68 D69 E75 S76A68-N72 WeakPolarHBondContact O-CB 3.4Å; A68-N72 PolarHBondContact O-N 2.93Å; A68-N72 PolarHBondContact O-ND2 3.1Å; A68-N72 VanDerWaalsContact O-ND2 3.08Å; D69-N72 PolarHBondContact O-N 2.94Å; N72-E75 PolarHBondContact O-N 2.78Å; N72-S76 WeakPolarHBondContact O-CB 3.13Å; N72-S76 PolarHBondContact O-N 3.05Å; N72-S76 PolarHBondContact O-OG 2.94Å
73M85Confident72.1Confident35 Ų3584.2 Ų84.217%0.17240%0.398CS..Hα-helixtrans-61.8-44.3174.1-73.1171.461.800111.8R8 I9 D69 L70 L71 S76 D77R8-M73 HydrophobicContact CB-CE 3.85Å; I9-M73 HydrophobicContact CG1-CE 4.43Å; D69-M73 WeakPolarHBondContact O-CG 3.17Å; D69-M73 PolarHBondContact O-N 2.76Å; L70-M73 HydrophobicContact CD2-SD 3.98Å; L70-M73 WeakPolarHBondContact O-CB 3.49Å; L70-M73 PolarHBondContact O-N 2.71Å; L71-M73 VanDerWaalsContact C-N 3.28Å; L71-M73 PolarHBondContact O-N 2.79Å; M73-S76 PolarHBondContact O-N 2.87Å; M73-S76 PolarHBondContact O-OG 2.76Å; M73-D77 PolarHBondContact O-N 2.81Å
74L79.6Confident69.8Low7 Ų784.4 Ų84.44%0.03741%0.411CS..Hα-helixtrans-62.4-42.3174.2-72.4173.9000112.5M1 L5 I9 L58 A59 F62 L70 L71 S76 S78M1-L74 HydrophobicContact SD-CD2 4.39Å; L5-L74 HydrophobicContact CD2-CD2 3.98Å; I9-L74 HydrophobicContact CD1-CD2 3.75Å; I9-L74 HydrophobicContact CD1-CG 4.26Å; L58-L74 HydrophobicContact CB-CD1 3.68Å; L58-L74 HydrophobicContact CB-CD2 4.33Å; L58-L74 HydrophobicContact CD1-CD2 4.13Å; A59-L74 HydrophobicContact CB-CD1 4.18Å; F62-L74 HydrophobicContact CD2-CD1 3.47Å; F62-L74 VanDerWaalsContact CD2-CD1 3.47Å; F62-L74 HydrophobicContact CD2-CG 4.26Å; F62-L74 HydrophobicContact CE2-CD1 3.56Å; F62-L74 HydrophobicContact CE2-CG 4.08Å; L70-L74 WeakPolarHBondContact O-CG 3.47Å; L70-L74 PolarHBondContact O-N 3.44Å; L71-L74 WeakPolarHBondContact O-CB 3.41Å; L71-L74 PolarHBondContact O-N 2.81Å; L74-S76 VanDerWaalsContact C-N 3.31Å; L74-S76 PolarHBondContact O-N 3Å; L74-S78 WeakPolarHBondContact O-CB 3.39Å; L74-S78 PolarHBondContact O-N 3.17Å; L74-S78 PolarHBondContact O-OG 2.79Å
75E72.1Confident67.5Low109 Ų10985.8 Ų85.851%0.50942%0.417SS..Hα-helixtrans-69.1-28.8-179.6-71.4-178.9-178.200112.5L71 N72 S78L71-E75 WeakPolarHBondContact O-CG 3.39Å; L71-E75 PolarHBondContact O-N 2.87Å; N72-E75 PolarHBondContact O-N 2.78Å; E75-S78 VanDerWaalsContact CA-OG 3.3Å; E75-S78 WeakPolarHBondContact CA-OG 3.49Å; E75-S78 PolarHBondContact O-OG 3.41Å
76S67.3Low65.1Low99 Ų9986.1 Ų86.169%0.69242%0.421SS*.Hα-helixtrans-77.5-26.8178.272.10000114.7N72 M73 L74N72-S76 WeakPolarHBondContact O-CB 3.13Å; N72-S76 PolarHBondContact O-N 3.05Å; N72-S76 PolarHBondContact O-OG 2.94Å; M73-S76 PolarHBondContact O-N 2.87Å; M73-S76 PolarHBondContact O-OG 2.76Å; L74-S76 VanDerWaalsContact C-N 3.31Å; L74-S76 PolarHBondContact O-N 3Å
77D61Low62.7Low73 Ų7378 Ų7839%0.3939%0.392SS..Hα-helixtrans-94.2-16.4179.4-161.346.9000112.6N2 L5 M73 R79N2-D77 WeakPolarHBondContact CB-OD2 3.5Å; N2-D77 PolarHBondContact ND2-OD2 3.07Å; L5-D77 HydrophobicContact CD1-CB 4.21Å; L5-D77 HydrophobicContact CD2-CB 3.86Å; L5-D77 WeakPolarHBondContact CD2-OD2 3.37Å; M73-D77 PolarHBondContact O-N 2.81Å; D77-R79 PolarHBondContact O-N 3.07Å; D77-R79 VanDerWaalsContact O-N 3.08Å
78S52.6Low60.4Low49 Ų4976.9 Ų76.934%0.34339%0.388SS..  trans-78.396.1-177.236.50000111.9L74 E75 E80L74-S78 WeakPolarHBondContact O-CB 3.39Å; L74-S78 PolarHBondContact O-N 3.17Å; L74-S78 PolarHBondContact O-OG 2.79Å; E75-S78 VanDerWaalsContact CA-OG 3.3Å; E75-S78 WeakPolarHBondContact CA-OG 3.49Å; E75-S78 PolarHBondContact O-OG 3.41Å; S78-E80 PolarHBondContact O-N 3.46Å
79R49.7Very low58.8Low249 Ų24975.5 Ų75.594%0.9438%0.376SS*.  trans-68.8-0157.4-76.2-175.1177.8178.40.5113.4D77 R81D77-R79 PolarHBondContact O-N 3.07Å; D77-R79 VanDerWaalsContact O-N 3.08Å; R79-R81 PolarHBondContact O-N 2.81Å
80E42.3Very low57.7Low159 Ų15974.7 Ų74.774%0.74337%0.368SS*.  trans-96.590.9175.3-72.2175.6178.900109.2S78 E82S78-E80 PolarHBondContact O-N 3.46Å; E80-E82 PolarHBondContact O-N 3.5Å
81R45.1Very low57.1Low222 Ų22275.2 Ų75.284%0.83837%0.371SS*.  trans-68.7115.1171.3-69.8176.5177.1165.6-1.4108.5R79 E83R79-R81 PolarHBondContact O-N 2.81Å; R81-E83 PolarHBondContact O-N 3.07Å; R81-E83 VanDerWaalsContact O-N 3.12Å
82E42.1Very low57.2Low80 Ų8075.9 Ų75.937%0.37438%0.377SS..  trans-60.6110.9151.3-68.6-170.4142.600107T56 E80 T84 C87T56-E82 HydrophobicContact CG2-CG 4.43Å; T56-E82 WeakPolarHBondContact CG2-OE1 3.45Å; E80-E82 PolarHBondContact O-N 3.5Å; E82-T84 PolarHBondContact O-N 3.49Å; E82-C87 VanDerWaalsContact CD-SG 3.55Å; E82-C87 PolarHBondContact OE1-SG 3.04Å; E82-C87 WeakPolarHBondContact OE2-CB 3.38Å; E82-C87 PolarHBondContact OE2-SG 3.17Å
83E48.8Very low57.3Low96 Ų9675.8 Ų75.845%0.44937%0.374SS..  trans-74.2124.4161.7-72-160.7-156.400106.6R81 R228R81-E83 PolarHBondContact O-N 3.07Å; R81-E83 VanDerWaalsContact O-N 3.12Å; E83-R228 WeakPolarHBondContact OE2-CD 3.46Å; E83-R228 IonicContact OE2-CZ 3.75Å; E83-R228 IonicContact OE2-NE 2.81Å; E83-R228 IonicContact OE2-NH1 3.07Å; E83-R228 PolarHBondContact OE2-NH1 2.73Å
84T38.2Very low57.6Low100 Ų10074.3 Ų74.361%0.61337%0.367SS*.SBendtrans-54.9156.8-174.449.40000109.7E82E82-T84 PolarHBondContact O-N 3.49Å
85D37.2Very low58.3Low56 Ų5674.5 Ų74.530%0.29937%0.367SS..SBendcis-140.747.432.5-60.635.1000115.6K378 Y380D85-K378 IonicContact OD2-NZ 3.72Å; D85-K378 PolarHBondContact OD2-NZ 2.99Å; D85-Y380 VanDerWaalsContact C-CD1 3.46Å; D85-Y380 HydrophobicContact CB-CD1 3.67Å; D85-Y380 HydrophobicContact CB-CE1 3.39Å; D85-Y380 WeakPolarHBondContact O-CD1 3.43Å; D85-Y380 WeakPolarHBondContact O-CE1 3.47Å
86A38.9Very low59Low21 Ų2172 Ų7217%0.17436%0.357CS..  153.2160.6119.600000117.4M425 R427A86-M425 CarbonylContact C-O 3.58Å; A86-M425 VanDerWaalsContact C-O 3.24Å; A86-R427 HydrophobicContact CB-CB 3.87Å; A86-R427 HydrophobicContact CB-CG 3.49Å; A86-R427 VanDerWaalsContact CB-CG 3.49Å
87C36.8Very low60.3Low8 Ų867.9 Ų67.95%0.05433%0.327CS..  trans-68136-168.1-158.60000115.5E82E82-C87 VanDerWaalsContact CD-SG 3.55Å; E82-C87 PolarHBondContact OE1-SG 3.04Å; E82-C87 WeakPolarHBondContact OE2-CB 3.38Å; E82-C87 PolarHBondContact OE2-SG 3.17Å
88P41.8Very low61.9Low5 Ų564.4 Ų64.43%0.03231%0.308CS..  trans-63.9130171.718.7-25.1000115.6Y90 F424 M425P88-Y90 HydrophobicContact CB-CD2 4.32Å; P88-Y90 HydrophobicContact CB-CE2 3.91Å; P88-Y90 HydrophobicContact CG-CE2 3.64Å; P88-Y90 WeakPolarHBondContact CG-OH 3.38Å; P88-Y90 WeakPolarHBondContact O-CD2 3.46Å; P88-Y90 WeakPolarHBondContact O-CE2 3.48Å; P88-F424 HydrophobicContact CB-CD2 4.17Å; P88-F424 HydrophobicContact CB-CE2 3.45Å; P88-F424 VanDerWaalsContact CB-CE2 3.45Å; P88-F424 HydrophobicContact CB-CZ 4.43Å; P88-M425 HydrophobicContact CB-CE 3.83Å; P88-M425 HydrophobicContact CB-CG 3.72Å; P88-M425 HydrophobicContact CB-SD 4.22Å; P88-M425 HydrophobicContact CG-CE 3.83Å
89A51.1Low63.8Low28 Ų2862.5 Ų62.523%0.23129%0.293CS..  trans-74104.6150.900000113.7E60 F424E60-A89 WeakPolarHBondContact OE1-CA 3.48Å; E60-A89 WeakPolarHBondContact OE1-CB 3.34Å; E60-A89 WeakPolarHBondContact OE2-CA 3.27Å; A89-F424 VanDerWaalsContact C-CD2 3.49Å; A89-F424 HydrophobicContact CB-CB 3.69Å; A89-F424 HydrophobicContact CB-CD2 3.75Å; A89-F424 HydrophobicContact CB-CG 4.12Å; A89-F424 WeakPolarHBondContact O-CD2 3.43Å; A89-F424 WeakPolarHBondContact O-CE2 3.31Å; A89-F424 WeakPolarHBondContact O-CG 3.46Å
90Y65.1Low65.7Low55 Ų5555.9 Ų55.922%0.21627%0.272CS..  trans-86.3-17.4174.6-58-100.6000114.1N54 T56 F57 E60 P88N54-Y90 PolarHBondContact OD1-OH 2.85Å; T56-Y90 WeakPolarHBondContact OG1-CE2 3.31Å; T56-Y90 PolarHBondContact OG1-OH 3.34Å; F57-Y90 HydrophobicContact CB-CD1 4.49Å; F57-Y90 HydrophobicContact CB-CD2 4.09Å; F57-Y90 HydrophobicContact CB-CE2 4.27Å; F57-Y90 HydrophobicContact CB-CG 4.26Å; F57-Y90 AromaticContact CD2-CD1 3.92Å; F57-Y90 HydrophobicContact CD2-CD1 3.92Å; F57-Y90 AromaticContact CD2-CD2 3.91Å; F57-Y90 HydrophobicContact CD2-CD2 3.91Å; F57-Y90 AromaticContact CD2-CG 3.44Å; F57-Y90 HydrophobicContact CD2-CG 3.44Å; F57-Y90 VanDerWaalsContact CD2-CG 3.44Å; F57-Y90 VanDerWaalsContact CE2-CB 3.4Å; F57-Y90 HydrophobicContact CE2-CG 4.19Å; F57-Y90 HydrophobicContact CG-CG 4.35Å; E60-Y90 VanDerWaalsContact CD-N 3.3Å; E60-Y90 PolarHBondContact OE1-N 2.76Å; E60-Y90 WeakPolarHBondContact OE2-CA 3.47Å; E60-Y90 VanDerWaalsContact OE2-CB 3.29Å; E60-Y90 WeakPolarHBondContact OE2-CB 3.28Å; E60-Y90 WeakPolarHBondContact OE2-CD2 3.06Å; E60-Y90 PolarHBondContact OE2-N 2.61Å; P88-Y90 HydrophobicContact CB-CD2 4.32Å; P88-Y90 HydrophobicContact CB-CE2 3.91Å; P88-Y90 HydrophobicContact CG-CE2 3.64Å; P88-Y90 WeakPolarHBondContact CG-OH 3.38Å; P88-Y90 WeakPolarHBondContact O-CD2 3.46Å; P88-Y90 WeakPolarHBondContact O-CE2 3.48Å
91L77.8Confident68Low11 Ų1148.3 Ų48.36%0.05824%0.236CC..SBendtrans-81.1136.5175.9-62.5175.8000109.9L24 F57 E60 L61 T64 L96L24-L91 HydrophobicContact CB-CD1 4.37Å; L24-L91 HydrophobicContact CB-CD2 4.06Å; L24-L91 HydrophobicContact CD1-CD1 4.27Å; L24-L91 HydrophobicContact CD2-CD1 4.39Å; F57-L91 HydrophobicContact CE2-CD2 4.05Å; F57-L91 HydrophobicContact CZ-CD2 4.13Å; E60-L91 HydrophobicContact CG-CD1 4.06Å; E60-L91 HydrophobicContact CG-CG 4.25Å; E60-L91 WeakPolarHBondContact OE1-CB 3.3Å; E60-L91 PolarHBondContact OE1-N 2.89Å; E60-L91 VanDerWaalsContact OE1-N 3.07Å; E60-L91 PolarHBondContact OE2-N 3.34Å; E60-L91 VanDerWaalsContact OE2-N 3.14Å; L61-L91 HydrophobicContact CD2-CD1 3.98Å; L61-L91 HydrophobicContact CD2-CD2 3.85Å; L61-L91 HydrophobicContact CD2-CG 4.44Å; L61-L91 HydrophobicContact CG-CD1 4.5Å; T64-L91 HydrophobicContact CG2-CD1 4.43Å; L91-L96 HydrophobicContact CB-CD2 4.07Å; L91-L96 HydrophobicContact CB-CG 4.13Å; L91-L96 HydrophobicContact CD1-CD2 4.06Å
92S85.4Confident70.2Confident37 Ų3739.1 Ų39.126%0.25920%0.203SC..  trans-66.2144.118074.50000110.9D27 Y94 R95 L96D27-S92 VanDerWaalsContact OD2-CB 3.24Å; D27-S92 WeakPolarHBondContact OD2-CB 3.06Å; D27-S92 PolarHBondContact OD2-OG 2.78Å; S92-Y94 PolarHBondContact O-N 2.84Å; S92-Y94 VanDerWaalsContact O-N 3.08Å; S92-R95 PolarHBondContact O-N 2.82Å; S92-R95 VanDerWaalsContact OG-CG 3.25Å; S92-R95 WeakPolarHBondContact OG-CG 3.44Å; S92-R95 PolarHBondContact OG-N 2.75Å; S92-R95 VanDerWaalsContact OG-N 3.13Å; S92-L96 PolarHBondContact O-N 2.78Å
93E85.7Confident72.5Confident93 Ų9339 Ų3944%0.43520%0.202SC..Hα-helixtrans-54-31.2174.2-76-166.7-163.400112.1M97 Y172 R175E93-M97 VanDerWaalsContact O-CB 3.27Å; E93-M97 WeakPolarHBondContact O-CB 3.26Å; E93-M97 PolarHBondContact O-N 2.62Å; E93-Y172 HydrophobicContact CB-CD2 4.35Å; E93-Y172 HydrophobicContact CB-CE2 3.94Å; E93-R175 IonicContact OE2-CZ 3.84Å; E93-R175 IonicContact OE2-NE 3.91Å; E93-R175 PolarHBondContact OE2-NE 3.3Å; E93-R175 IonicContact OE2-NH2 2.66Å; E93-R175 PolarHBondContact OE2-NH2 3.05Å
94Y91.4Very high74.3Confident3 Ų338.2 Ų38.21%0.01220%0.201CC..Hα-helixtrans-63.5-48.7175174.5-110.3000112.2S92 M97 L98 E140 S146 K147 V150 Y172S92-Y94 PolarHBondContact O-N 2.84Å; S92-Y94 VanDerWaalsContact O-N 3.08Å; Y94-M97 HydrophobicContact CD2-CE 4.03Å; Y94-M97 HydrophobicContact CE2-CE 4.33Å; Y94-M97 WeakPolarHBondContact O-CB 3.21Å; Y94-M97 PolarHBondContact O-N 2.98Å; Y94-L98 HydrophobicContact CD1-CD1 4.36Å; Y94-L98 HydrophobicContact CE1-CD1 3.73Å; Y94-L98 HydrophobicContact CE2-CD1 3.91Å; Y94-L98 HydrophobicContact CE2-CG 4.25Å; Y94-L98 VanDerWaalsContact CZ-CD1 3.48Å; Y94-L98 WeakPolarHBondContact O-CG 3.31Å; Y94-L98 PolarHBondContact O-N 2.86Å; Y94-E140 WeakPolarHBondContact CE1-OE1 3.49Å; Y94-E140 WeakPolarHBondContact OH-CG 3.36Å; Y94-E140 PolarHBondContact OH-OE1 2.95Å; Y94-S146 VanDerWaalsContact CE2-C 3.43Å; Y94-S146 VanDerWaalsContact CE2-O 3.31Å; Y94-S146 WeakPolarHBondContact CE2-O 3.28Å; Y94-K147 HydrophobicContact CD1-CB 4.08Å; Y94-K147 HydrophobicContact CD2-CB 4.39Å; Y94-K147 HydrophobicContact CG-CB 3.96Å; Y94-V150 HydrophobicContact CD2-CG1 4.26Å; Y94-V150 HydrophobicContact CE2-CG1 4.06Å; Y94-Y172 WeakPolarHBondContact CB-OH 3.13Å; Y94-Y172 HydrophobicContact CD2-CE1 4.25Å
95R93.1Very high76.7Confident12 Ų1234.2 Ų34.25%0.04518%0.176CC..Hα-helixtrans-64.6-41.6176.8-69.4-72170.3-151.2-11.8111.5F23 L24 D27 S92 M97 L98 Y99 E140F23-R95 WeakPolarHBondContact O-CD 3.49Å; L24-R95 HydrophobicContact CD2-CB 4.33Å; D27-R95 IonicContact OD1-CZ 3.83Å; D27-R95 VanDerWaalsContact OD1-CZ 3.32Å; D27-R95 IonicContact OD1-NE 3.57Å; D27-R95 PolarHBondContact OD1-NE 3.44Å; D27-R95 IonicContact OD1-NH2 2.85Å; D27-R95 PolarHBondContact OD1-NH2 3.11Å; D27-R95 VanDerWaalsContact OD2-CG 3.25Å; D27-R95 WeakPolarHBondContact OD2-CG 3.32Å; D27-R95 IonicContact OD2-NE 3.4Å; S92-R95 PolarHBondContact O-N 2.82Å; S92-R95 VanDerWaalsContact OG-CG 3.25Å; S92-R95 WeakPolarHBondContact OG-CG 3.44Å; S92-R95 PolarHBondContact OG-N 2.75Å; S92-R95 VanDerWaalsContact OG-N 3.13Å; R95-M97 VanDerWaalsContact C-N 3.34Å; R95-M97 PolarHBondContact O-N 3.17Å; R95-L98 PolarHBondContact O-N 2.79Å; R95-Y99 WeakPolarHBondContact O-CB 3.46Å; R95-Y99 PolarHBondContact O-N 2.66Å; R95-E140 IonicContact CZ-OE1 3.57Å; R95-E140 IonicContact CZ-OE2 2.74Å; R95-E140 IonicContact NH1-OE1 3.32Å; R95-E140 PolarHBondContact NH1-OE1 3.01Å; R95-E140 IonicContact NH1-OE2 3.02Å; R95-E140 PolarHBondContact NH1-OE2 3Å; R95-E140 IonicContact NH2-OE1 2.91Å; R95-E140 PolarHBondContact NH2-OE1 3.43Å; R95-E140 IonicContact NH2-OE2 2.93Å; R95-E140 PolarHBondContact NH2-OE2 3.09Å
96L88.8Confident79.2Confident56 Ų5635.1 Ų35.129%0.29318%0.183SC..Hα-helixtrans-62.3-40.8175.6-66.6176.2000111.9T64 L91 S92 K100T64-L96 HydrophobicContact CG2-CD2 3.71Å; L91-L96 HydrophobicContact CB-CD2 4.07Å; L91-L96 HydrophobicContact CB-CG 4.13Å; L91-L96 HydrophobicContact CD1-CD2 4.06Å; S92-L96 PolarHBondContact O-N 2.78Å; L96-K100 WeakPolarHBondContact O-CB 3.43Å; L96-K100 PolarHBondContact O-N 3.27Å
97M93.6Very high81.6Confident13 Ų1340.3 Ų40.36%0.06421%0.208CC..Hα-helixtrans-61.9-50.2175-179.4-16164.200111.1E93 Y94 R95 Y99 K100 I101 V150 L153 T168 V169 Y172E93-M97 VanDerWaalsContact O-CB 3.27Å; E93-M97 WeakPolarHBondContact O-CB 3.26Å; E93-M97 PolarHBondContact O-N 2.62Å; Y94-M97 HydrophobicContact CD2-CE 4.03Å; Y94-M97 HydrophobicContact CE2-CE 4.33Å; Y94-M97 WeakPolarHBondContact O-CB 3.21Å; Y94-M97 PolarHBondContact O-N 2.98Å; R95-M97 VanDerWaalsContact C-N 3.34Å; R95-M97 PolarHBondContact O-N 3.17Å; M97-Y99 VanDerWaalsContact C-N 3.33Å; M97-Y99 PolarHBondContact O-N 2.68Å; M97-K100 PolarHBondContact O-N 3.14Å; M97-I101 HydrophobicContact CE-CD1 4.43Å; M97-I101 HydrophobicContact CG-CD1 3.83Å; M97-I101 WeakPolarHBondContact O-CD1 2.99Å; M97-I101 VanDerWaalsContact O-CG1 3.22Å; M97-I101 WeakPolarHBondContact O-CG1 3.37Å; M97-I101 PolarHBondContact O-N 2.78Å; M97-I101 HydrophobicContact SD-CD1 4.34Å; M97-V150 HydrophobicContact CE-CG1 4.04Å; M97-L153 HydrophobicContact CE-CD2 3.75Å; M97-T168 HydrophobicContact CG-CG2 4.13Å; M97-V169 HydrophobicContact SD-CB 4.45Å; M97-V169 HydrophobicContact SD-CG1 4.41Å; M97-V169 HydrophobicContact SD-CG2 4.36Å; M97-Y172 HydrophobicContact CE-CD1 4.29Å; M97-Y172 HydrophobicContact CE-CG 4.38Å; M97-Y172 WeakPolarHBondContact SD-CB 3.45Å; M97-Y172 HydrophobicContact SD-CD1 3.91Å; M97-Y172 HydrophobicContact SD-CD2 4.16Å; M97-Y172 HydrophobicContact SD-CG 3.54Å; M97-Y172 VanDerWaalsContact SD-CG 3.54Å
98L94.1Very high84.1Confident0 Ų044.2 Ų44.20%023%0.229CC..Hα-helixtrans-62.4-40.7179.6-68.6-178.5000112.2F23 Y94 R95 I101 H102 F136 I145 L153F23-L98 HydrophobicContact CE1-CB 3.98Å; F23-L98 HydrophobicContact CZ-CB 3.72Å; F23-L98 HydrophobicContact CZ-CD1 3.73Å; F23-L98 HydrophobicContact CZ-CG 4.39Å; Y94-L98 HydrophobicContact CD1-CD1 4.36Å; Y94-L98 HydrophobicContact CE1-CD1 3.73Å; Y94-L98 HydrophobicContact CE2-CD1 3.91Å; Y94-L98 HydrophobicContact CE2-CG 4.25Å; Y94-L98 VanDerWaalsContact CZ-CD1 3.48Å; Y94-L98 WeakPolarHBondContact O-CG 3.31Å; Y94-L98 PolarHBondContact O-N 2.86Å; R95-L98 PolarHBondContact O-N 2.79Å; L98-I101 PolarHBondContact O-N 3.37Å; L98-H102 PolarHBondContact O-N 2.62Å; L98-F136 HydrophobicContact CB-CD2 4.06Å; L98-F136 HydrophobicContact CB-CE2 4.49Å; L98-F136 HydrophobicContact CD1-CB 4.36Å; L98-F136 HydrophobicContact CD2-CD2 3.99Å; L98-F136 HydrophobicContact CD2-CE2 4.36Å; L98-F136 HydrophobicContact CD2-CG 4.1Å; L98-F136 HydrophobicContact CG-CD2 4.48Å; L98-F136 WeakPolarHBondContact O-CE2 3.37Å; L98-I145 HydrophobicContact CD2-CD1 4.38Å; L98-L153 HydrophobicContact CD2-CD2 3.47Å; L98-L153 VanDerWaalsContact CD2-CD2 3.47Å
99Y93.3Very high86.4Confident8 Ų846.4 Ų46.43%0.03124%0.238CC..Hα-helixtrans-65.3-41.9177.2-167.3-90.3000111.9E20 L24 T64 T65 R95 M97 I101 H102 E103 L133E20-Y99 HydrophobicContact CB-CE2 3.98Å; E20-Y99 HydrophobicContact CG-CE2 4.03Å; E20-Y99 PolarHBondContact OE2-OH 3.49Å; L24-Y99 HydrophobicContact CD1-CD2 4.21Å; L24-Y99 HydrophobicContact CD1-CE2 4.32Å; L24-Y99 HydrophobicContact CD2-CD2 3.88Å; L24-Y99 HydrophobicContact CD2-CG 3.96Å; L24-Y99 HydrophobicContact CG-CD2 4.08Å; T64-Y99 HydrophobicContact CG2-CD1 3.71Å; T64-Y99 HydrophobicContact CG2-CE1 4.09Å; T64-Y99 HydrophobicContact CG2-CG 4.1Å; T64-Y99 VanDerWaalsContact O-CE1 3.24Å; T64-Y99 WeakPolarHBondContact O-CE1 3.38Å; T65-Y99 WeakPolarHBondContact CA-OH 3.17Å; T65-Y99 HydrophobicContact CG2-CE2 4.4Å; R95-Y99 WeakPolarHBondContact O-CB 3.46Å; R95-Y99 PolarHBondContact O-N 2.66Å; M97-Y99 VanDerWaalsContact C-N 3.33Å; M97-Y99 PolarHBondContact O-N 2.68Å; Y99-I101 PolarHBondContact O-N 2.94Å; Y99-H102 WeakPolarHBondContact O-CB 3.22Å; Y99-H102 PolarHBondContact O-N 2.69Å; Y99-E103 HydrophobicContact CD1-CG 4.18Å; Y99-E103 HydrophobicContact CE1-CG 3.86Å; Y99-E103 PolarHBondContact O-N 3.5Å; Y99-L133 HydrophobicContact CD2-CD1 4.09Å; Y99-L133 HydrophobicContact CD2-CD2 4.34Å; Y99-L133 HydrophobicContact CE2-CD1 4.17Å
100K89.8Confident88.3Confident111 Ų11145.3 Ų45.348%0.48323%0.228SC..Hα-helixtrans-61.6-43.3173.9-176.7178.1179.2-175.60112.2L96 M97 H102 E103 D104 T168L96-K100 WeakPolarHBondContact O-CB 3.43Å; L96-K100 PolarHBondContact O-N 3.27Å; M97-K100 PolarHBondContact O-N 3.14Å; K100-H102 VanDerWaalsContact C-N 3.26Å; K100-H102 PolarHBondContact O-N 2.8Å; K100-E103 PolarHBondContact O-N 3.01Å; K100-D104 PolarHBondContact O-N 3.08Å; K100-T168 HydrophobicContact CD-CG2 4.44Å
101I90.4Very high89.6Confident0 Ų047.8 Ų47.80%024%0.242CC..Hα-helixtrans-61.8-39.2176.6-67.9165.5000110.2M97 L98 Y99 D104 L105 F136 L153 M157 L165 T168 V169M97-I101 HydrophobicContact CE-CD1 4.43Å; M97-I101 HydrophobicContact CG-CD1 3.83Å; M97-I101 WeakPolarHBondContact O-CD1 2.99Å; M97-I101 VanDerWaalsContact O-CG1 3.22Å; M97-I101 WeakPolarHBondContact O-CG1 3.37Å; M97-I101 PolarHBondContact O-N 2.78Å; M97-I101 HydrophobicContact SD-CD1 4.34Å; L98-I101 PolarHBondContact O-N 3.37Å; Y99-I101 PolarHBondContact O-N 2.94Å; I101-D104 PolarHBondContact O-N 3.41Å; I101-L105 HydrophobicContact CG2-CD1 3.58Å; I101-L105 HydrophobicContact CG2-CG 4.23Å; I101-L105 VanDerWaalsContact O-CB 3.3Å; I101-L105 WeakPolarHBondContact O-CB 3.34Å; I101-L105 WeakPolarHBondContact O-CD1 3.15Å; I101-L105 VanDerWaalsContact O-CG 3.22Å; I101-L105 WeakPolarHBondContact O-CG 3.39Å; I101-L105 PolarHBondContact O-N 2.92Å; I101-F136 HydrophobicContact CB-CE2 4.38Å; I101-F136 HydrophobicContact CB-CZ 4.35Å; I101-F136 HydrophobicContact CG2-CE2 4.09Å; I101-F136 HydrophobicContact CG2-CZ 3.59Å; I101-L153 HydrophobicContact CD1-CD2 3.99Å; I101-M157 HydrophobicContact CG2-CE 4.4Å; I101-M157 HydrophobicContact CG2-SD 3.81Å; I101-L165 HydrophobicContact CB-CD2 4.48Å; I101-L165 HydrophobicContact CG1-CD2 4.17Å; I101-L165 HydrophobicContact CG2-CD1 4.11Å; I101-T168 HydrophobicContact CG1-CG2 4.47Å; I101-V169 HydrophobicContact CD1-CG2 3.45Å; I101-V169 VanDerWaalsContact CD1-CG2 3.45Å
102H92.1Very high90.2Very high29 Ų2949.7 Ų49.713%0.13425%0.253CS..Hα-helixtrans-61.1-47.2175.5163.246.2000113L98 Y99 K100 D104 L105 A132 L133 F136L98-H102 PolarHBondContact O-N 2.62Å; Y99-H102 WeakPolarHBondContact O-CB 3.22Å; Y99-H102 PolarHBondContact O-N 2.69Å; K100-H102 VanDerWaalsContact C-N 3.26Å; K100-H102 PolarHBondContact O-N 2.8Å; H102-D104 PolarHBondContact O-N 3.01Å; H102-L105 PolarHBondContact O-N 3.38Å; H102-A132 HydrophobicContact CB-CB 3.98Å; H102-L133 HydrophobicContact CB-CD2 3.54Å; H102-L133 HydrophobicContact CB-CG 3.91Å; H102-L133 VanDerWaalsContact CD2-CG 3.41Å; H102-L133 WeakPolarHBondContact CD2-CG 3.27Å; H102-F136 HydrophobicContact CB-CE2 4.36Å
103E89.6Confident90.5Very high76 Ų7647.9 Ų47.936%0.35524%0.241SC..Hα-helixtrans-61-34179-78.9-81.394.200112.8R66 Y99 K100R66-E103 IonicContact CZ-OE2 3Å; R66-E103 IonicContact NE-OE2 3.38Å; R66-E103 IonicContact NH1-OE2 3.64Å; R66-E103 IonicContact NH2-OE2 2.86Å; Y99-E103 HydrophobicContact CD1-CG 4.18Å; Y99-E103 HydrophobicContact CE1-CG 3.86Å; Y99-E103 PolarHBondContact O-N 3.5Å; K100-E103 PolarHBondContact O-N 3.01Å
104D86.3Confident90.9Very high81 Ų8144.5 Ų44.543%0.43323%0.225SC..THydrogen-bonded Turntrans-95.3-0.7-175.9-71.5-19.8000112.6K100 I101 H102 L165K100-D104 PolarHBondContact O-N 3.08Å; I101-D104 PolarHBondContact O-N 3.41Å; H102-D104 PolarHBondContact O-N 3.01Å; D104-L165 HydrophobicContact CB-CD1 4.29Å; D104-L165 HydrophobicContact CB-CD2 3.72Å; D104-L165 HydrophobicContact CB-CG 4.44Å
105L88.9Confident90.9Very high16 Ų1652 Ų528%0.08426%0.258CS..  trans-92.5128.5177-93.3163.8000111I101 H102 K109 V110 L113 A132 F136 L165I101-L105 HydrophobicContact CG2-CD1 3.58Å; I101-L105 HydrophobicContact CG2-CG 4.23Å; I101-L105 VanDerWaalsContact O-CB 3.3Å; I101-L105 WeakPolarHBondContact O-CB 3.34Å; I101-L105 WeakPolarHBondContact O-CD1 3.15Å; I101-L105 VanDerWaalsContact O-CG 3.22Å; I101-L105 WeakPolarHBondContact O-CG 3.39Å; I101-L105 PolarHBondContact O-N 2.92Å; H102-L105 PolarHBondContact O-N 3.38Å; L105-K109 HydrophobicContact CD2-CB 3.56Å; L105-V110 HydrophobicContact CB-CG2 4.28Å; L105-L113 HydrophobicContact CD1-CD1 3.75Å; L105-L113 HydrophobicContact CD2-CD1 3.94Å; L105-A132 HydrophobicContact CB-CB 4.46Å; L105-A132 HydrophobicContact CD1-CB 3.7Å; L105-F136 HydrophobicContact CD1-CZ 3.73Å; L105-L165 HydrophobicContact CD2-CD1 4.28Å; L105-L165 HydrophobicContact CG-CD1 3.86Å
106T89.2Confident90.7Very high74 Ų7454 Ų5445%0.45427%0.269SS..  trans-83155.7171.556.10000111.6D108 K109 V110T106-D108 VanDerWaalsContact C-N 3.27Å; T106-D108 WeakPolarHBondContact CB-OD1 3.31Å; T106-D108 PolarHBondContact O-N 2.95Å; T106-D108 PolarHBondContact OG1-OD1 3.24Å; T106-K109 WeakPolarHBondContact O-CA 3.46Å; T106-K109 WeakPolarHBondContact O-CB 3.41Å; T106-K109 PolarHBondContact O-N 3.12Å; T106-K109 WeakPolarHBondContact OG1-CG 3.33Å; T106-V110 PolarHBondContact O-N 2.72Å
107D89Confident90.9Very high131 Ų13151.3 Ų51.370%0.70126%0.255SS*.Hα-helixtrans-56.7-38-178.3-66.6-22.9000113K109 V110 E111D107-K109 VanDerWaalsContact C-N 3.26Å; D107-K109 PolarHBondContact O-N 2.97Å; D107-V110 WeakPolarHBondContact O-CB 3.47Å; D107-V110 PolarHBondContact O-N 3.3Å; D107-E111 PolarHBondContact O-N 3.4Å
108D89Confident90.7Very high90 Ų9053.9 Ų53.948%0.48127%0.269SS..Hα-helixtrans-62.9-34.5176.169.1-74.8000112.3T106 E111 T112T106-D108 VanDerWaalsContact C-N 3.27Å; T106-D108 WeakPolarHBondContact CB-OD1 3.31Å; T106-D108 PolarHBondContact O-N 2.95Å; T106-D108 PolarHBondContact OG1-OD1 3.24Å; D108-E111 PolarHBondContact O-N 3.19Å; D108-T112 PolarHBondContact O-N 2.95Å; D108-T112 PolarHBondContact O-OG1 3.33Å
109K90.4Very high90.5Very high51 Ų5160.1 Ų60.122%0.22230%0.303CS..Hα-helixtrans-76.2-32.5176.5-61.5-62.8177.6174.10111.3L105 T106 D107 T112 L113 T160L105-K109 HydrophobicContact CD2-CB 3.56Å; T106-K109 WeakPolarHBondContact O-CA 3.46Å; T106-K109 WeakPolarHBondContact O-CB 3.41Å; T106-K109 PolarHBondContact O-N 3.12Å; T106-K109 WeakPolarHBondContact OG1-CG 3.33Å; D107-K109 VanDerWaalsContact C-N 3.26Å; D107-K109 PolarHBondContact O-N 2.97Å; K109-T112 WeakPolarHBondContact O-CB 3.49Å; K109-T112 PolarHBondContact O-N 3.16Å; K109-L113 VanDerWaalsContact O-CG 3.31Å; K109-L113 WeakPolarHBondContact O-CG 3.44Å; K109-L113 PolarHBondContact O-N 3.01Å; K109-T160 WeakPolarHBondContact CD-O 3.29Å; K109-T160 WeakPolarHBondContact CE-O 3.23Å; K109-T160 PolarHBondContact NZ-O 2.77Å
110V91.7Very high90.5Very high5 Ų563.2 Ų63.23%0.0332%0.317CS..Hα-helixtrans-62.8-43.3170.51780000111L105 T106 D107 T112 L113 K114 A132 V135L105-V110 HydrophobicContact CB-CG2 4.28Å; T106-V110 PolarHBondContact O-N 2.72Å; D107-V110 WeakPolarHBondContact O-CB 3.47Å; D107-V110 PolarHBondContact O-N 3.3Å; V110-T112 VanDerWaalsContact C-N 3.33Å; V110-T112 PolarHBondContact O-N 3.26Å; V110-L113 WeakPolarHBondContact O-CB 3.35Å; V110-L113 PolarHBondContact O-N 2.92Å; V110-K114 WeakPolarHBondContact O-CG 3.47Å; V110-K114 PolarHBondContact O-N 3.05Å; V110-A132 HydrophobicContact CG2-CB 3.94Å; V110-V135 HydrophobicContact CG1-CG2 4.21Å
111E91.9Very high90.6Very high107 Ų10758.2 Ų58.250%0.530%0.296SS..Hα-helixtrans-64.1-39.3174.5-68.7-53.9129.800112.2D107 D108 L113 K114 F115D107-E111 PolarHBondContact O-N 3.4Å; D108-E111 PolarHBondContact O-N 3.19Å; E111-L113 VanDerWaalsContact C-N 3.34Å; E111-L113 PolarHBondContact O-N 2.81Å; E111-K114 PolarHBondContact O-N 2.79Å; E111-K114 IonicContact OE1-NZ 2.67Å; E111-K114 PolarHBondContact OE1-NZ 3.38Å; E111-K114 IonicContact OE2-NZ 3.52Å; E111-F115 PolarHBondContact O-N 3.31Å
112T90.8Very high90.6Very high50 Ų5061 Ų6131%0.30732%0.318SS..Hα-helixtrans-61.3-43.1173.2-55.60000111.3D108 K109 V110 K114 F115 L116 T160D108-T112 PolarHBondContact O-N 2.95Å; D108-T112 PolarHBondContact O-OG1 3.33Å; K109-T112 WeakPolarHBondContact O-CB 3.49Å; K109-T112 PolarHBondContact O-N 3.16Å; V110-T112 VanDerWaalsContact C-N 3.33Å; V110-T112 PolarHBondContact O-N 3.26Å; T112-K114 PolarHBondContact O-N 3.27Å; T112-F115 WeakPolarHBondContact O-CB 3.25Å; T112-F115 PolarHBondContact O-N 3.38Å; T112-L116 HydrophobicContact CG2-CD1 4.12Å; T112-L116 HydrophobicContact CG2-CG 4.48Å; T112-L116 VanDerWaalsContact O-CG 3.31Å; T112-L116 WeakPolarHBondContact O-CG 3.26Å; T112-L116 PolarHBondContact O-N 3.49Å; T112-T160 HydrophobicContact CG2-CG2 3.87Å
113L92.1Very high90.4Very high0 Ų065.8 Ų65.80%034%0.339CS..Hα-helixtrans-59.7-47175.8-74.9172.1000111.8L105 K109 V110 E111 F115 L116 V117 F136 L156 M157 T160L105-L113 HydrophobicContact CD1-CD1 3.75Å; L105-L113 HydrophobicContact CD2-CD1 3.94Å; K109-L113 VanDerWaalsContact O-CG 3.31Å; K109-L113 WeakPolarHBondContact O-CG 3.44Å; K109-L113 PolarHBondContact O-N 3.01Å; V110-L113 WeakPolarHBondContact O-CB 3.35Å; V110-L113 PolarHBondContact O-N 2.92Å; E111-L113 VanDerWaalsContact C-N 3.34Å; E111-L113 PolarHBondContact O-N 2.81Å; L113-F115 VanDerWaalsContact C-N 3.29Å; L113-F115 PolarHBondContact O-N 2.84Å; L113-L116 PolarHBondContact O-N 3.22Å; L113-V117 WeakPolarHBondContact O-CG2 3.41Å; L113-V117 PolarHBondContact O-N 3.06Å; L113-F136 HydrophobicContact CD1-CE1 4.42Å; L113-L156 HydrophobicContact CD2-CB 3.71Å; L113-L156 HydrophobicContact CD2-CD1 4.39Å; L113-L156 HydrophobicContact CD2-CD2 4.45Å; L113-L156 HydrophobicContact CD2-CG 4.41Å; L113-M157 HydrophobicContact CD1-CE 4.04Å; L113-M157 HydrophobicContact CD2-CE 3.67Å; L113-M157 HydrophobicContact CG-CE 4.44Å; L113-T160 HydrophobicContact CD2-CG2 3.77Å; L113-T160 HydrophobicContact CG-CG2 4.01Å
114K93Very high90.3Very high22 Ų2271.1 Ų71.110%0.09636%0.356CS..Hα-helixtrans-56.9-45.2176.4-70.2173.3-176.41730111.4V110 E111 T112 L116 V117 N118 L126 S129 V135V110-K114 WeakPolarHBondContact O-CG 3.47Å; V110-K114 PolarHBondContact O-N 3.05Å; E111-K114 PolarHBondContact O-N 2.79Å; E111-K114 IonicContact OE1-NZ 2.67Å; E111-K114 PolarHBondContact OE1-NZ 3.38Å; E111-K114 IonicContact OE2-NZ 3.52Å; T112-K114 PolarHBondContact O-N 3.27Å; K114-L116 VanDerWaalsContact C-N 3.33Å; K114-L116 PolarHBondContact O-N 3.23Å; K114-V117 PolarHBondContact O-N 2.83Å; K114-N118 WeakPolarHBondContact O-CB 3.39Å; K114-N118 PolarHBondContact O-N 2.97Å; K114-L126 HydrophobicContact CB-CB 4.49Å; K114-L126 HydrophobicContact CG-CB 4.41Å; K114-L126 HydrophobicContact CG-CD2 4.42Å; K114-L126 WeakPolarHBondContact O-CD1 3.49Å; K114-S129 WeakPolarHBondContact CE-O 3.05Å; K114-S129 PolarHBondContact NZ-O 2.87Å; K114-V135 HydrophobicContact CG-CG2 3.82Å
115F91.2Very high90.3Very high161 Ų16170.6 Ų70.671%0.70635%0.351SS*.Hα-helixtrans-59.7-44.2178.3179.3-98.9000111.9E111 T112 L113 V117 N118E111-F115 PolarHBondContact O-N 3.31Å; T112-F115 WeakPolarHBondContact O-CB 3.25Å; T112-F115 PolarHBondContact O-N 3.38Å; L113-F115 VanDerWaalsContact C-N 3.29Å; L113-F115 PolarHBondContact O-N 2.84Å; F115-V117 VanDerWaalsContact C-N 3.29Å; F115-V117 PolarHBondContact O-N 3.2Å; F115-N118 PolarHBondContact O-N 3.36Å
116L89.9Confident90.3Very high52 Ų5270 Ų7027%0.27235%0.348SS..Hα-helixtrans-69.6-19-178.2-69173000114.6T112 L113 K114 L156 N159 T160T112-L116 HydrophobicContact CG2-CD1 4.12Å; T112-L116 HydrophobicContact CG2-CG 4.48Å; T112-L116 VanDerWaalsContact O-CG 3.31Å; T112-L116 WeakPolarHBondContact O-CG 3.26Å; T112-L116 PolarHBondContact O-N 3.49Å; L113-L116 PolarHBondContact O-N 3.22Å; K114-L116 VanDerWaalsContact C-N 3.33Å; K114-L116 PolarHBondContact O-N 3.23Å; L116-L156 HydrophobicContact CB-CD2 3.5Å; L116-L156 HydrophobicContact CD1-CD2 3.89Å; L116-L156 HydrophobicContact CG-CD2 4.34Å; L116-N159 HydrophobicContact CD1-CB 3.86Å; L116-T160 HydrophobicContact CD1-CG2 4.12Å
117V92.7Very high90.2Very high0 Ų071.9 Ų71.90%036%0.355CS..Hα-helixtrans-110.13.7179.4-56.50000113.8L113 K114 F115 D119 Q120 I121 L126 M139 L156L113-V117 WeakPolarHBondContact O-CG2 3.41Å; L113-V117 PolarHBondContact O-N 3.06Å; K114-V117 PolarHBondContact O-N 2.83Å; F115-V117 VanDerWaalsContact C-N 3.29Å; F115-V117 PolarHBondContact O-N 3.2Å; V117-D119 PolarHBondContact O-N 3.26Å; V117-Q120 PolarHBondContact O-N 3.49Å; V117-I121 HydrophobicContact CB-CD1 4.2Å; V117-I121 HydrophobicContact CG2-CD1 3.89Å; V117-I121 HydrophobicContact CG2-CG1 4.49Å; V117-I121 PolarHBondContact O-N 2.74Å; V117-L126 HydrophobicContact CG2-CD1 4.03Å; V117-L126 HydrophobicContact CG2-CD2 3.84Å; V117-M139 HydrophobicContact CG1-SD 4.46Å; V117-L156 HydrophobicContact CG1-CD1 3.59Å; V117-L156 HydrophobicContact CG1-CD2 3.99Å; V117-L156 HydrophobicContact CG1-CG 4.44Å
118N90.4Very high90.1Very high67 Ų6772.6 Ų72.636%0.35835%0.352SS..THydrogen-bonded Turntrans-68.4-13.1-175.1-177.245.9000114.2K114 F115 K123 L126K114-N118 WeakPolarHBondContact O-CB 3.39Å; K114-N118 PolarHBondContact O-N 2.97Å; F115-N118 PolarHBondContact O-N 3.36Å; N118-K123 WeakPolarHBondContact OD1-CB 3.29Å; N118-L126 HydrophobicContact CB-CD1 3.99Å
119D89.1Confident90Very high132 Ų13268.5 Ų68.571%0.70633%0.33SS*.THydrogen-bonded Turntrans-82.3-23.2171.565.2-25000113V117V117-D119 PolarHBondContact O-N 3.26Å
120Q92.8Very high89.8Confident73 Ų7370.3 Ų70.334%0.34135%0.349SS..THydrogen-bonded Turntrans-107.1-25.1-176.3-70.1154.884.700113V117 L144V117-Q120 PolarHBondContact O-N 3.49Å; Q120-L144 HydrophobicContact CB-CD1 3.76Å; Q120-L144 HydrophobicContact CB-CD2 4.14Å; Q120-L144 HydrophobicContact CG-CD2 4.28Å
121I92.1Very high89.7Confident6 Ų672.2 Ų72.23%0.03136%0.361CS..SBendtrans-119.4136179.2-56176.8000108.9V117 K123 Q125 L126 E138 M139 A142 L144V117-I121 HydrophobicContact CB-CD1 4.2Å; V117-I121 HydrophobicContact CG2-CD1 3.89Å; V117-I121 HydrophobicContact CG2-CG1 4.49Å; V117-I121 PolarHBondContact O-N 2.74Å; I121-K123 PolarHBondContact O-N 3.32Å; I121-Q125 HydrophobicContact CG2-CB 4.18Å; I121-L126 HydrophobicContact CB-CD1 4.16Å; I121-L126 HydrophobicContact CB-CD2 4.11Å; I121-L126 HydrophobicContact CB-CG 4.13Å; I121-L126 HydrophobicContact CD1-CD2 4.23Å; I121-L126 HydrophobicContact CG2-CD1 4.37Å; I121-L126 HydrophobicContact CG2-CD2 3.8Å; I121-L126 HydrophobicContact CG2-CG 3.81Å; I121-E138 HydrophobicContact CD1-CB 4.13Å; I121-E138 HydrophobicContact CG2-CB 4.08Å; I121-M139 HydrophobicContact CD1-CB 4.28Å; I121-M139 HydrophobicContact CD1-CG 3.64Å; I121-A142 HydrophobicContact CG1-CB 3.97Å; I121-L144 HydrophobicContact CD1-CD1 4.04Å; I121-L144 HydrophobicContact CG1-CD1 4.01Å
122A90.4Very high89.7Confident57 Ų5767.1 Ų67.147%0.47134%0.337SS..  trans-62.3129-177.200000111.3R124 Q125 L126A122-R124 PolarHBondContact O-N 2.81Å; A122-Q125 HydrophobicContact CB-CG 4.46Å; A122-Q125 WeakPolarHBondContact O-CA 3.36Å; A122-Q125 WeakPolarHBondContact O-CB 3.42Å; A122-Q125 PolarHBondContact O-N 3.47Å; A122-L126 PolarHBondContact O-N 2.61Å
123K87.3Confident89.8Confident131 Ų13165 Ų6557%0.5732%0.324SS*.Hα-helixtrans-45.6-43.1-179.4-170.8174.8179177.10114.1N118 I121 Q125 L126 D127N118-K123 WeakPolarHBondContact OD1-CB 3.29Å; I121-K123 PolarHBondContact O-N 3.32Å; K123-Q125 PolarHBondContact O-N 3.42Å; K123-L126 PolarHBondContact O-N 2.84Å; K123-L126 VanDerWaalsContact O-N 3.13Å; K123-D127 PolarHBondContact O-N 2.59Å
124R88Confident89.8Confident188 Ų18868 Ų6871%0.70934%0.34SS*.Hα-helixtrans-57.9-29.9177.4-175.4-178.9-179.5-162.90.5113.9A122 K128A122-R124 PolarHBondContact O-N 2.81Å; R124-K128 WeakPolarHBondContact O-CG 3.11Å
125Q87.1Confident89.8Confident70 Ų7066.9 Ų66.933%0.32734%0.335SS..Hα-helixtrans-79.7-40.7177.5-69170.1-28.600111I121 A122 K123 K128 S129 E138I121-Q125 HydrophobicContact CG2-CB 4.18Å; A122-Q125 HydrophobicContact CB-CG 4.46Å; A122-Q125 WeakPolarHBondContact O-CA 3.36Å; A122-Q125 WeakPolarHBondContact O-CB 3.42Å; A122-Q125 PolarHBondContact O-N 3.47Å; K123-Q125 PolarHBondContact O-N 3.42Å; Q125-K128 PolarHBondContact O-N 3.17Å; Q125-S129 PolarHBondContact O-N 3.33Å; Q125-S129 PolarHBondContact O-OG 2.75Å; Q125-E138 HydrophobicContact CB-CG 4.32Å; Q125-E138 WeakPolarHBondContact CB-OE2 3.34Å; Q125-E138 PolarHBondContact OE1-OE2 3.02Å
126L88.8Confident90Very high4 Ų459.2 Ų59.22%0.02130%0.302CS..Hα-helixtrans-67-38176.8-63.3174000112.2K114 V117 N118 I121 A122 K123 K128 S129K114-L126 HydrophobicContact CB-CB 4.49Å; K114-L126 HydrophobicContact CG-CB 4.41Å; K114-L126 HydrophobicContact CG-CD2 4.42Å; K114-L126 WeakPolarHBondContact O-CD1 3.49Å; V117-L126 HydrophobicContact CG2-CD1 4.03Å; V117-L126 HydrophobicContact CG2-CD2 3.84Å; N118-L126 HydrophobicContact CB-CD1 3.99Å; I121-L126 HydrophobicContact CB-CD1 4.16Å; I121-L126 HydrophobicContact CB-CD2 4.11Å; I121-L126 HydrophobicContact CB-CG 4.13Å; I121-L126 HydrophobicContact CD1-CD2 4.23Å; I121-L126 HydrophobicContact CG2-CD1 4.37Å; I121-L126 HydrophobicContact CG2-CD2 3.8Å; I121-L126 HydrophobicContact CG2-CG 3.81Å; A122-L126 PolarHBondContact O-N 2.61Å; K123-L126 PolarHBondContact O-N 2.84Å; K123-L126 VanDerWaalsContact O-N 3.13Å; L126-K128 PolarHBondContact O-N 2.9Å; L126-S129 WeakPolarHBondContact O-CB 3.23Å; L126-S129 PolarHBondContact O-N 3.41Å
127D87.4Confident90.1Very high113 Ų11357.8 Ų57.860%0.60430%0.297SS*.THydrogen-bonded Turntrans-61.8-27.1176.2-67.1-20.7000112.4K123K123-D127 PolarHBondContact O-N 2.59Å
128K85.3Confident90.1Very high145 Ų14559 Ų5963%0.6330%0.303SS*.THydrogen-bonded Turntrans-86.3-10.7176.3-69.4179.7177.2-169.30113.6R124 Q125 L126 S130R124-K128 WeakPolarHBondContact O-CG 3.11Å; Q125-K128 PolarHBondContact O-N 3.17Å; L126-K128 PolarHBondContact O-N 2.9Å; K128-S130 PolarHBondContact O-N 2.98Å
129S87.2Confident90.3Very high4 Ų455.8 Ų55.83%0.02829%0.286CS..  trans-88.3104.2-176.4-62.90000108.8K114 Q125 L126K114-S129 WeakPolarHBondContact CE-O 3.05Å; K114-S129 PolarHBondContact NZ-O 2.87Å; Q125-S129 PolarHBondContact O-N 3.33Å; Q125-S129 PolarHBondContact O-OG 2.75Å; L126-S129 WeakPolarHBondContact O-CB 3.23Å; L126-S129 PolarHBondContact O-N 3.41Å
130S85.9Confident90.5Very high90 Ų9051.7 Ų51.763%0.62926%0.262SS*.  trans-88.2-18.4-17951.40000113.8K128K128-S130 PolarHBondContact O-N 2.98Å
131T90.1Very high90.3Very high44 Ų4453.8 Ų53.827%0.2727%0.27SS..SBendtrans-124.1162.8-176.466.80000111.2L133 N134 V135T131-L133 PolarHBondContact O-N 3.37Å; T131-N134 PolarHBondContact O-N 3.02Å; T131-N134 PolarHBondContact OG1-N 2.97Å; T131-N134 PolarHBondContact OG1-OD1 3.36Å; T131-V135 PolarHBondContact O-N 3.45Å
132A92.1Very high90.3Very high1 Ų155.8 Ų55.81%0.00829%0.288CS..Hα-helixtrans-58.1-37.8172.400000112H102 L105 V110 N134 V135 F136H102-A132 HydrophobicContact CB-CB 3.98Å; L105-A132 HydrophobicContact CB-CB 4.46Å; L105-A132 HydrophobicContact CD1-CB 3.7Å; V110-A132 HydrophobicContact CG2-CB 3.94Å; A132-N134 VanDerWaalsContact C-N 3.32Å; A132-N134 PolarHBondContact O-N 3.42Å; A132-V135 PolarHBondContact O-N 2.94Å; A132-V135 VanDerWaalsContact O-N 3.15Å; A132-F136 HydrophobicContact CB-CE2 3.89Å; A132-F136 HydrophobicContact CB-CZ 3.96Å; A132-F136 VanDerWaalsContact O-CD2 3.27Å; A132-F136 WeakPolarHBondContact O-CD2 3.01Å; A132-F136 WeakPolarHBondContact O-CG 3.35Å; A132-F136 PolarHBondContact O-N 2.9Å
133L93.6Very high90.3Very high6 Ų655.8 Ų55.83%0.03129%0.293CS..Hα-helixtrans-59.3-41.1176.7-61.2-176.6000112.4E20 F23 Y99 H102 T131 V135 F136 A137E20-L133 HydrophobicContact CB-CD1 4.47Å; E20-L133 HydrophobicContact CG-CD1 3.89Å; F23-L133 HydrophobicContact CB-CD1 4.18Å; F23-L133 HydrophobicContact CD1-CD1 4.19Å; F23-L133 HydrophobicContact CD1-CD2 3.69Å; F23-L133 HydrophobicContact CD1-CG 4.4Å; F23-L133 HydrophobicContact CD2-CB 3.95Å; F23-L133 HydrophobicContact CD2-CD2 4.22Å; F23-L133 HydrophobicContact CE1-CD2 3.57Å; F23-L133 HydrophobicContact CE2-CB 4.25Å; F23-L133 HydrophobicContact CE2-CD2 4.1Å; F23-L133 HydrophobicContact CG-CB 4.18Å; F23-L133 HydrophobicContact CG-CD1 4.09Å; F23-L133 HydrophobicContact CG-CD2 4.03Å; F23-L133 HydrophobicContact CG-CG 4.33Å; F23-L133 HydrophobicContact CZ-CD2 3.77Å; Y99-L133 HydrophobicContact CD2-CD1 4.09Å; Y99-L133 HydrophobicContact CD2-CD2 4.34Å; Y99-L133 HydrophobicContact CE2-CD1 4.17Å; H102-L133 HydrophobicContact CB-CD2 3.54Å; H102-L133 HydrophobicContact CB-CG 3.91Å; H102-L133 VanDerWaalsContact CD2-CG 3.41Å; H102-L133 WeakPolarHBondContact CD2-CG 3.27Å; T131-L133 PolarHBondContact O-N 3.37Å; L133-V135 VanDerWaalsContact C-N 3.34Å; L133-F136 HydrophobicContact CD2-CD2 4.32Å; L133-F136 PolarHBondContact O-N 3.35Å; L133-A137 WeakPolarHBondContact O-CB 3.32Å; L133-A137 PolarHBondContact O-N 2.96Å
134N91.1Very high90.6Very high61 Ų6150.9 Ų50.933%0.32627%0.273SS..Hα-helixtrans-65-41.1176.9-68.631000111.1T131 A132 A137 E138T131-N134 PolarHBondContact O-N 3.02Å; T131-N134 PolarHBondContact OG1-N 2.97Å; T131-N134 PolarHBondContact OG1-OD1 3.36Å; A132-N134 VanDerWaalsContact C-N 3.32Å; A132-N134 PolarHBondContact O-N 3.42Å; N134-A137 PolarHBondContact O-N 2.99Å; N134-E138 PolarHBondContact O-N 3.35Å; N134-E138 VanDerWaalsContact O-N 3.07Å
135V93.6Very high90.9Very high0 Ų042 Ų420%024%0.24CC..Hα-helixtrans-63.3-44.8176.1179.80000110.4V110 K114 T131 A132 L133 A137 E138 M139V110-V135 HydrophobicContact CG1-CG2 4.21Å; K114-V135 HydrophobicContact CG-CG2 3.82Å; T131-V135 PolarHBondContact O-N 3.45Å; A132-V135 PolarHBondContact O-N 2.94Å; A132-V135 VanDerWaalsContact O-N 3.15Å; L133-V135 VanDerWaalsContact C-N 3.34Å; V135-A137 VanDerWaalsContact C-N 3.35Å; V135-A137 PolarHBondContact O-N 3.31Å; V135-E138 PolarHBondContact O-N 2.86Å; V135-M139 HydrophobicContact CG1-CG 4.41Å; V135-M139 HydrophobicContact CG1-SD 4.01Å; V135-M139 VanDerWaalsContact O-CG 3.28Å; V135-M139 WeakPolarHBondContact O-CG 3.45Å; V135-M139 PolarHBondContact O-N 3.42Å
136F95.4Very high91.2Very high0 Ų040.9 Ų40.90%024%0.239CC..Hα-helixtrans-60.8-42.7175.9-58.3-29.2000111.9F23 L98 I101 H102 L105 L113 A132 L133 E138 M139 E140 I145 L153F23-F136 HydrophobicContact CE2-CB 4.36Å; L98-F136 HydrophobicContact CB-CD2 4.06Å; L98-F136 HydrophobicContact CB-CE2 4.49Å; L98-F136 HydrophobicContact CD1-CB 4.36Å; L98-F136 HydrophobicContact CD2-CD2 3.99Å; L98-F136 HydrophobicContact CD2-CE2 4.36Å; L98-F136 HydrophobicContact CD2-CG 4.1Å; L98-F136 HydrophobicContact CG-CD2 4.48Å; L98-F136 WeakPolarHBondContact O-CE2 3.37Å; I101-F136 HydrophobicContact CB-CE2 4.38Å; I101-F136 HydrophobicContact CB-CZ 4.35Å; I101-F136 HydrophobicContact CG2-CE2 4.09Å; I101-F136 HydrophobicContact CG2-CZ 3.59Å; H102-F136 HydrophobicContact CB-CE2 4.36Å; L105-F136 HydrophobicContact CD1-CZ 3.73Å; L113-F136 HydrophobicContact CD1-CE1 4.42Å; A132-F136 HydrophobicContact CB-CE2 3.89Å; A132-F136 HydrophobicContact CB-CZ 3.96Å; A132-F136 VanDerWaalsContact O-CD2 3.27Å; A132-F136 WeakPolarHBondContact O-CD2 3.01Å; A132-F136 WeakPolarHBondContact O-CG 3.35Å; A132-F136 PolarHBondContact O-N 2.9Å; L133-F136 HydrophobicContact CD2-CD2 4.32Å; L133-F136 PolarHBondContact O-N 3.35Å; F136-E138 VanDerWaalsContact C-N 3.3Å; F136-E138 PolarHBondContact O-N 3.49Å; F136-M139 HydrophobicContact CD1-SD 4.07Å; F136-M139 WeakPolarHBondContact O-CB 3.46Å; F136-M139 PolarHBondContact O-N 3.29Å; F136-M139 VanDerWaalsContact O-N 3.15Å; F136-E140 WeakPolarHBondContact O-CG 3.41Å; F136-E140 PolarHBondContact O-N 3.48Å; F136-I145 HydrophobicContact CB-CD1 4.2Å; F136-L153 HydrophobicContact CD1-CD1 4.13Å; F136-L153 HydrophobicContact CE1-CD1 3.75Å; F136-L153 HydrophobicContact CZ-CD1 4.47Å
137A91.2Very high91.3Very high22 Ų2246.4 Ų46.418%0.18226%0.263CS..Hα-helixtrans-62.9-33.517700000113R31 L133 N134 V135 K141R31-A137 PolarHBondContact NH1-O 3.36Å; L133-A137 WeakPolarHBondContact O-CB 3.32Å; L133-A137 PolarHBondContact O-N 2.96Å; N134-A137 PolarHBondContact O-N 2.99Å; V135-A137 VanDerWaalsContact C-N 3.35Å; V135-A137 PolarHBondContact O-N 3.31Å; A137-K141 PolarHBondContact O-N 3.1Å; A137-K141 VanDerWaalsContact O-N 3.17Å
138E92.7Very high91.4Very high25 Ų2545.3 Ų45.312%0.11726%0.258CS..Hα-helixtrans-75.4-35.5172.8-68.4-55.2108.300112.2R31 I121 Q125 N134 V135 F136 E140 K141 A142R31-E138 IonicContact CZ-OE1 3.85Å; R31-E138 IonicContact NH2-OE1 3.96Å; R31-E138 PolarHBondContact NH2-OE1 3.25Å; I121-E138 HydrophobicContact CD1-CB 4.13Å; I121-E138 HydrophobicContact CG2-CB 4.08Å; Q125-E138 HydrophobicContact CB-CG 4.32Å; Q125-E138 WeakPolarHBondContact CB-OE2 3.34Å; Q125-E138 PolarHBondContact OE1-OE2 3.02Å; N134-E138 PolarHBondContact O-N 3.35Å; N134-E138 VanDerWaalsContact O-N 3.07Å; V135-E138 PolarHBondContact O-N 2.86Å; F136-E138 VanDerWaalsContact C-N 3.3Å; F136-E138 PolarHBondContact O-N 3.49Å; E138-E140 VanDerWaalsContact C-N 3.33Å; E138-E140 PolarHBondContact O-N 3.23Å; E138-K141 VanDerWaalsContact O-CB 3.3Å; E138-K141 WeakPolarHBondContact O-CB 3.39Å; E138-K141 PolarHBondContact O-N 3.27Å; E138-A142 WeakPolarHBondContact O-CB 3.45Å; E138-A142 PolarHBondContact O-N 3.25Å
139M94.3Very high91.7Very high0 Ų041.6 Ų41.60%025%0.245CC..Hα-helixtrans-63.2-39.3172.5-68.1169.86400111.9V117 I121 V135 F136 K141 A142 G143 L144 I145 L153 L156V117-M139 HydrophobicContact CG1-SD 4.46Å; I121-M139 HydrophobicContact CD1-CB 4.28Å; I121-M139 HydrophobicContact CD1-CG 3.64Å; V135-M139 HydrophobicContact CG1-CG 4.41Å; V135-M139 HydrophobicContact CG1-SD 4.01Å; V135-M139 VanDerWaalsContact O-CG 3.28Å; V135-M139 WeakPolarHBondContact O-CG 3.45Å; V135-M139 PolarHBondContact O-N 3.42Å; F136-M139 HydrophobicContact CD1-SD 4.07Å; F136-M139 WeakPolarHBondContact O-CB 3.46Å; F136-M139 PolarHBondContact O-N 3.29Å; F136-M139 VanDerWaalsContact O-N 3.15Å; M139-K141 VanDerWaalsContact C-N 3.34Å; M139-A142 PolarHBondContact O-N 2.69Å; M139-G143 PolarHBondContact O-N 3.39Å; M139-L144 HydrophobicContact CB-CB 4.27Å; M139-L144 HydrophobicContact CG-CD1 4.38Å; M139-L144 WeakPolarHBondContact O-CB 3.29Å; M139-L144 PolarHBondContact O-N 3.36Å; M139-I145 HydrophobicContact CB-CD1 3.82Å; M139-I145 HydrophobicContact CB-CG1 3.76Å; M139-I145 HydrophobicContact CE-CD1 4.19Å; M139-I145 HydrophobicContact CE-CG2 3.59Å; M139-L153 HydrophobicContact CE-CD1 4.26Å; M139-L156 HydrophobicContact CE-CD1 3.34Å; M139-L156 HydrophobicContact SD-CD1 4.16Å
140E93.7Very high92.1Very high46 Ų4641.4 Ų41.422%0.21524%0.243CC..Hα-helixtrans-62-42.2171.9-72-174.5118.700111.6Y94 R95 F136 E138 A142 G143 I145Y94-E140 WeakPolarHBondContact CE1-OE1 3.49Å; Y94-E140 WeakPolarHBondContact OH-CG 3.36Å; Y94-E140 PolarHBondContact OH-OE1 2.95Å; R95-E140 IonicContact CZ-OE1 3.57Å; R95-E140 IonicContact CZ-OE2 2.74Å; R95-E140 IonicContact NH1-OE1 3.32Å; R95-E140 PolarHBondContact NH1-OE1 3.01Å; R95-E140 IonicContact NH1-OE2 3.02Å; R95-E140 PolarHBondContact NH1-OE2 3Å; R95-E140 IonicContact NH2-OE1 2.91Å; R95-E140 PolarHBondContact NH2-OE1 3.43Å; R95-E140 IonicContact NH2-OE2 2.93Å; R95-E140 PolarHBondContact NH2-OE2 3.09Å; F136-E140 WeakPolarHBondContact O-CG 3.41Å; F136-E140 PolarHBondContact O-N 3.48Å; E138-E140 VanDerWaalsContact C-N 3.33Å; E138-E140 PolarHBondContact O-N 3.23Å; E140-A142 VanDerWaalsContact C-N 3.31Å; E140-A142 PolarHBondContact O-N 2.91Å; E140-G143 PolarHBondContact O-N 3.02Å; E140-I145 HydrophobicContact CG-CD1 4.08Å; E140-I145 HydrophobicContact CG-CG1 3.74Å
141K90.1Very high92.4Very high117 Ų11740.5 Ų40.551%0.50923%0.231SC..Hα-helixtrans-62.1-40.3178.4-160179.8-177.3166.80112.6A137 E138 M139 G143A137-K141 PolarHBondContact O-N 3.1Å; A137-K141 VanDerWaalsContact O-N 3.17Å; E138-K141 VanDerWaalsContact O-CB 3.3Å; E138-K141 WeakPolarHBondContact O-CB 3.39Å; E138-K141 PolarHBondContact O-N 3.27Å; M139-K141 VanDerWaalsContact C-N 3.34Å; K141-G143 PolarHBondContact O-N 3.13Å
142A91.4Very high92.5Very high48 Ų4840.2 Ų40.240%0.39723%0.226SC..THydrogen-bonded Turntrans-78.2-2.5177.800000112.5I121 E138 M139 E140 L144I121-A142 HydrophobicContact CG1-CB 3.97Å; E138-A142 WeakPolarHBondContact O-CB 3.45Å; E138-A142 PolarHBondContact O-N 3.25Å; M139-A142 PolarHBondContact O-N 2.69Å; E140-A142 VanDerWaalsContact C-N 3.31Å; E140-A142 PolarHBondContact O-N 2.91Å; A142-L144 HydrophobicContact CB-CD1 4.24Å; A142-L144 HydrophobicContact CB-CG 3.88Å; A142-L144 PolarHBondContact O-N 3.1Å
143G90.5Very high92.6Very high57 Ų5740.2 Ų40.259%0.58823%0.226SC*.THydrogen-bonded Turntrans71.116.8-179.400000113.9M139 E140 K141M139-G143 PolarHBondContact O-N 3.39Å; E140-G143 PolarHBondContact O-N 3.02Å; K141-G143 PolarHBondContact O-N 3.13Å
144L92.9Very high92.6Very high27 Ų2741.8 Ų41.814%0.14123%0.233CC..SBendtrans-76.3-31.3-179.4-58.1-176.8000112.1Q120 I121 M139 A142 K152Q120-L144 HydrophobicContact CB-CD1 3.76Å; Q120-L144 HydrophobicContact CB-CD2 4.14Å; Q120-L144 HydrophobicContact CG-CD2 4.28Å; I121-L144 HydrophobicContact CD1-CD1 4.04Å; I121-L144 HydrophobicContact CG1-CD1 4.01Å; M139-L144 HydrophobicContact CB-CB 4.27Å; M139-L144 HydrophobicContact CG-CD1 4.38Å; M139-L144 WeakPolarHBondContact O-CB 3.29Å; M139-L144 PolarHBondContact O-N 3.36Å; A142-L144 HydrophobicContact CB-CD1 4.24Å; A142-L144 HydrophobicContact CB-CG 3.88Å; A142-L144 PolarHBondContact O-N 3.1Å; L144-K152 HydrophobicContact CB-CG 4.33Å; L144-K152 WeakPolarHBondContact O-CB 3.42Å
145I95.3Very high92.7Very high3 Ų342.7 Ų42.72%0.01524%0.235CC..  trans-135.3150.3176.865.6175.8000109.9L98 F136 M139 E140 N149 K152 L153L98-I145 HydrophobicContact CD2-CD1 4.38Å; F136-I145 HydrophobicContact CB-CD1 4.2Å; M139-I145 HydrophobicContact CB-CD1 3.82Å; M139-I145 HydrophobicContact CB-CG1 3.76Å; M139-I145 HydrophobicContact CE-CD1 4.19Å; M139-I145 HydrophobicContact CE-CG2 3.59Å; E140-I145 HydrophobicContact CG-CD1 4.08Å; E140-I145 HydrophobicContact CG-CG1 3.74Å; I145-N149 CarbonylContact C-O 3.44Å; I145-N149 WeakPolarHBondContact CA-O 3.46Å; I145-K152 HydrophobicContact CG2-CB 4.36Å; I145-L153 HydrophobicContact CG2-CB 3.83Å
146S93.3Very high92.6Very high45 Ų4542.7 Ų42.732%0.31524%0.236SC..BIsolated β-bridgetrans-155.6173.2171.575.10000109.6Y94 D148 N149Y94-S146 VanDerWaalsContact CE2-C 3.43Å; Y94-S146 VanDerWaalsContact CE2-O 3.31Å; Y94-S146 WeakPolarHBondContact CE2-O 3.28Å; S146-D148 PolarHBondContact O-N 3.19Å; S146-D148 VanDerWaalsContact O-N 3.08Å; S146-D148 PolarHBondContact OG-N 3.35Å; S146-N149 PolarHBondContact N-O 3.44Å; S146-N149 CarbonylContact O-C 3.52Å; S146-N149 PolarHBondContact O-N 3.47Å; S146-N149 VanDerWaalsContact O-N 3.15Å; S146-N149 VanDerWaalsContact O-O 3.07Å; S146-N149 PolarHBondContact OG-N 2.88Å; S146-N149 VanDerWaalsContact OG-N 3.16Å
147K90.8Very high92.5Very high121 Ų12142.7 Ų42.753%0.52624%0.236SC..THydrogen-bonded Turntrans-53.8-27.7172.968.8177.9-173.51770113.6Y94 Y172 L176Y94-K147 HydrophobicContact CD1-CB 4.08Å; Y94-K147 HydrophobicContact CD2-CB 4.39Å; Y94-K147 HydrophobicContact CG-CB 3.96Å; K147-Y172 WeakPolarHBondContact O-CE1 3.47Å; K147-Y172 PolarHBondContact O-OH 3.42Å; K147-L176 WeakPolarHBondContact O-CD2 3.25Å
148D90Very high92.4Very high90 Ų9045.8 Ų45.848%0.48125%0.248SC..THydrogen-bonded Turntrans-105.1-7.9-175.8-55.8-53.3000112.6S146S146-D148 PolarHBondContact O-N 3.19Å; S146-D148 VanDerWaalsContact O-N 3.08Å; S146-D148 PolarHBondContact OG-N 3.35Å
149N91.5Very high92.1Very high67 Ų6748.3 Ų48.336%0.35826%0.262SS..BIsolated β-bridgetrans-143.9107.1179.5-177.93000110.8I145 S146 D151I145-N149 CarbonylContact C-O 3.44Å; I145-N149 WeakPolarHBondContact CA-O 3.46Å; S146-N149 PolarHBondContact N-O 3.44Å; S146-N149 CarbonylContact O-C 3.52Å; S146-N149 PolarHBondContact O-N 3.47Å; S146-N149 VanDerWaalsContact O-N 3.15Å; S146-N149 VanDerWaalsContact O-O 3.07Å; S146-N149 PolarHBondContact OG-N 2.88Å; S146-N149 VanDerWaalsContact OG-N 3.16Å; N149-D151 WeakPolarHBondContact OD1-CB 3.06Å; N149-D151 PolarHBondContact OD1-N 3.14Å; N149-D151 VanDerWaalsContact OD1-N 3.12Å
150V94.4Very high91.6Very high0 Ų048.4 Ų48.40%026%0.263CS..  trans-116.317.8178.3-61.80000112.3Y94 M97 K152 L153 H154 V169 Y172 K173 L176Y94-V150 HydrophobicContact CD2-CG1 4.26Å; Y94-V150 HydrophobicContact CE2-CG1 4.06Å; M97-V150 HydrophobicContact CE-CG1 4.04Å; V150-K152 PolarHBondContact O-N 2.97Å; V150-L153 HydrophobicContact CB-CB 4.44Å; V150-L153 WeakPolarHBondContact O-CB 3.28Å; V150-L153 PolarHBondContact O-N 3.07Å; V150-H154 PolarHBondContact O-N 3.35Å; V150-V169 HydrophobicContact CB-CG1 3.89Å; V150-V169 HydrophobicContact CG2-CG1 3.79Å; V150-Y172 HydrophobicContact CB-CD1 4.47Å; V150-Y172 HydrophobicContact CG1-CD1 3.81Å; V150-Y172 HydrophobicContact CG1-CE1 3.74Å; V150-Y172 HydrophobicContact CG2-CD1 3.9Å; V150-Y172 HydrophobicContact CG2-CE1 4.44Å; V150-K173 HydrophobicContact CG2-CB 3.73Å; V150-K173 HydrophobicContact CG2-CG 4.26Å; V150-L176 HydrophobicContact CG2-CD1 4.32Å
151D91.9Very high90.9Very high70 Ų7052.7 Ų52.737%0.37429%0.287SS..Hα-helixtrans-62.4-45.4-173.3-72.6-7.2000111.8N149 L153 H154 E155 K173N149-D151 WeakPolarHBondContact OD1-CB 3.06Å; N149-D151 PolarHBondContact OD1-N 3.14Å; N149-D151 VanDerWaalsContact OD1-N 3.12Å; D151-L153 VanDerWaalsContact C-N 3.31Å; D151-L153 PolarHBondContact O-N 2.96Å; D151-H154 PolarHBondContact O-N 3.32Å; D151-E155 PolarHBondContact O-N 3.09Å; D151-K173 VanDerWaalsContact CG-NZ 3.31Å; D151-K173 VanDerWaalsContact OD1-CD 3.27Å; D151-K173 WeakPolarHBondContact OD1-CD 3.24Å; D151-K173 WeakPolarHBondContact OD1-CE 3.49Å; D151-K173 IonicContact OD1-NZ 3.86Å; D151-K173 PolarHBondContact OD1-NZ 3.47Å; D151-K173 IonicContact OD2-NZ 3.35Å
152K93.6Very high90.4Very high39 Ų3948.6 Ų48.617%0.1727%0.271CS..Hα-helixtrans-64.9-37.7177.4-168.555.2173.7178.70111.7L144 I145 V150 E155 L156L144-K152 HydrophobicContact CB-CG 4.33Å; L144-K152 WeakPolarHBondContact O-CB 3.42Å; I145-K152 HydrophobicContact CG2-CB 4.36Å; V150-K152 PolarHBondContact O-N 2.97Å; K152-E155 VanDerWaalsContact CD-OE2 3.26Å; K152-E155 WeakPolarHBondContact CD-OE2 3.39Å; K152-E155 VanDerWaalsContact NZ-CD 3.28Å; K152-E155 IonicContact NZ-OE1 3.82Å; K152-E155 PolarHBondContact NZ-OE1 2.8Å; K152-E155 IonicContact NZ-OE2 3.88Å; K152-E155 PolarHBondContact NZ-OE2 2.71Å; K152-E155 PolarHBondContact O-N 2.96Å; K152-L156 HydrophobicContact CG-CD1 4.22Å; K152-L156 WeakPolarHBondContact O-CB 3.44Å; K152-L156 WeakPolarHBondContact O-CG 3.34Å; K152-L156 PolarHBondContact O-N 2.61Å
153L94.6Very high90Very high0 Ų050.6 Ų50.60%028%0.278CS..Hα-helixtrans-63.5-43.9176.1-170.963.1000111.4M97 L98 I101 F136 M139 I145 V150 D151 L156 M157 V169M97-L153 HydrophobicContact CE-CD2 3.75Å; L98-L153 HydrophobicContact CD2-CD2 3.47Å; L98-L153 VanDerWaalsContact CD2-CD2 3.47Å; I101-L153 HydrophobicContact CD1-CD2 3.99Å; F136-L153 HydrophobicContact CD1-CD1 4.13Å; F136-L153 HydrophobicContact CE1-CD1 3.75Å; F136-L153 HydrophobicContact CZ-CD1 4.47Å; M139-L153 HydrophobicContact CE-CD1 4.26Å; I145-L153 HydrophobicContact CG2-CB 3.83Å; V150-L153 HydrophobicContact CB-CB 4.44Å; V150-L153 WeakPolarHBondContact O-CB 3.28Å; V150-L153 PolarHBondContact O-N 3.07Å; D151-L153 VanDerWaalsContact C-N 3.31Å; D151-L153 PolarHBondContact O-N 2.96Å; L153-L156 PolarHBondContact O-N 3.43Å; L153-M157 HydrophobicContact CD1-CE 4.14Å; L153-M157 WeakPolarHBondContact O-CG 3.19Å; L153-M157 PolarHBondContact O-N 2.89Å; L153-V169 HydrophobicContact CB-CG1 4.22Å; L153-V169 HydrophobicContact CD2-CG1 4.19Å; L153-V169 HydrophobicContact CD2-CG2 3.88Å; L153-V169 HydrophobicContact CG-CG1 4.26Å; L153-V169 HydrophobicContact CG-CG2 3.92Å
154H93.4Very high89.7Confident39 Ų3952 Ų5218%0.18128%0.277CS..Hα-helixtrans-63-44.3178.6-178.9-101.7000111.7V150 D151 L156 M157 I158 A166 V169V150-H154 PolarHBondContact O-N 3.35Å; D151-H154 PolarHBondContact O-N 3.32Å; H154-L156 VanDerWaalsContact C-N 3.33Å; H154-L156 PolarHBondContact O-N 3.16Å; H154-M157 PolarHBondContact O-N 2.79Å; H154-I158 VanDerWaalsContact CE1-CD1 3.45Å; H154-I158 WeakPolarHBondContact CE1-CD1 3.17Å; H154-I158 WeakPolarHBondContact O-CG1 3.33Å; H154-I158 PolarHBondContact O-N 2.91Å; H154-I158 VanDerWaalsContact O-N 3.15Å; H154-A166 PolarHBondContact CD2-O 2.85Å; H154-A166 VanDerWaalsContact CD2-O 3.22Å; H154-V169 HydrophobicContact CB-CB 4.26Å; H154-V169 HydrophobicContact CB-CG1 3.7Å
155E92.8Very high89.5Confident80 Ų8050.9 Ų50.937%0.37427%0.271SS..Hα-helixtrans-56.7-47173.4-172.6-157.5137.600111.2D151 K152 M157 I158 N159D151-E155 PolarHBondContact O-N 3.09Å; K152-E155 VanDerWaalsContact CD-OE2 3.26Å; K152-E155 WeakPolarHBondContact CD-OE2 3.39Å; K152-E155 VanDerWaalsContact NZ-CD 3.28Å; K152-E155 IonicContact NZ-OE1 3.82Å; K152-E155 PolarHBondContact NZ-OE1 2.8Å; K152-E155 IonicContact NZ-OE2 3.88Å; K152-E155 PolarHBondContact NZ-OE2 2.71Å; K152-E155 PolarHBondContact O-N 2.96Å; E155-M157 PolarHBondContact O-N 3.38Å; E155-I158 WeakPolarHBondContact O-CB 3.41Å; E155-I158 PolarHBondContact O-N 3.48Å; E155-N159 VanDerWaalsContact O-CG 3.29Å; E155-N159 PolarHBondContact O-N 2.9Å; E155-N159 PolarHBondContact O-ND2 2.88Å
156L91.9Very high89.2Confident1 Ų151.1 Ų51.11%0.00527%0.274CS..Hα-helixtrans-65-38.4179.5-70.9168.8000112.8L113 L116 V117 M139 K152 L153 H154 I158 N159 T160L113-L156 HydrophobicContact CD2-CB 3.71Å; L113-L156 HydrophobicContact CD2-CD1 4.39Å; L113-L156 HydrophobicContact CD2-CD2 4.45Å; L113-L156 HydrophobicContact CD2-CG 4.41Å; L116-L156 HydrophobicContact CB-CD2 3.5Å; L116-L156 HydrophobicContact CD1-CD2 3.89Å; L116-L156 HydrophobicContact CG-CD2 4.34Å; V117-L156 HydrophobicContact CG1-CD1 3.59Å; V117-L156 HydrophobicContact CG1-CD2 3.99Å; V117-L156 HydrophobicContact CG1-CG 4.44Å; M139-L156 HydrophobicContact CE-CD1 3.34Å; M139-L156 HydrophobicContact SD-CD1 4.16Å; K152-L156 HydrophobicContact CG-CD1 4.22Å; K152-L156 WeakPolarHBondContact O-CB 3.44Å; K152-L156 WeakPolarHBondContact O-CG 3.34Å; K152-L156 PolarHBondContact O-N 2.61Å; L153-L156 PolarHBondContact O-N 3.43Å; H154-L156 VanDerWaalsContact C-N 3.33Å; H154-L156 PolarHBondContact O-N 3.16Å; L156-I158 VanDerWaalsContact C-N 3.27Å; L156-I158 PolarHBondContact O-N 2.96Å; L156-N159 PolarHBondContact O-N 3.44Å; L156-T160 WeakPolarHBondContact O-CB 3.44Å; L156-T160 WeakPolarHBondContact O-CG2 3.26Å; L156-T160 PolarHBondContact O-N 3.4Å; L156-T160 PolarHBondContact O-OG1 2.91Å
157M93.3Very high88.9Confident0 Ų056 Ų560%029%0.289CS..Hα-helixtrans-64.8-31175-67.3-54.797.800112.7I101 L113 L153 H154 E155 T160 N162 L165 A166 V169I101-M157 HydrophobicContact CG2-CE 4.4Å; I101-M157 HydrophobicContact CG2-SD 3.81Å; L113-M157 HydrophobicContact CD1-CE 4.04Å; L113-M157 HydrophobicContact CD2-CE 3.67Å; L113-M157 HydrophobicContact CG-CE 4.44Å; L153-M157 HydrophobicContact CD1-CE 4.14Å; L153-M157 WeakPolarHBondContact O-CG 3.19Å; L153-M157 PolarHBondContact O-N 2.89Å; H154-M157 PolarHBondContact O-N 2.79Å; E155-M157 PolarHBondContact O-N 3.38Å; M157-T160 WeakPolarHBondContact CA-OG1 3.32Å; M157-T160 PolarHBondContact O-OG1 3.37Å; M157-N162 PolarHBondContact O-N 3.18Å; M157-N162 VanDerWaalsContact O-N 3.11Å; M157-L165 HydrophobicContact CB-CB 4.48Å; M157-L165 HydrophobicContact CG-CB 4.12Å; M157-L165 HydrophobicContact SD-CB 3.64Å; M157-L165 HydrophobicContact SD-CD1 4.12Å; M157-A166 HydrophobicContact CB-CB 3.8Å; M157-V169 HydrophobicContact CG-CG2 3.77Å
158I88.3Confident88.8Confident87 Ų8752 Ų5245%0.44628%0.275SS..Hα-helixtrans-70.9-48.7172.2-67.3168.8000110.2H154 E155 L156 T160 D161 A166H154-I158 VanDerWaalsContact CE1-CD1 3.45Å; H154-I158 WeakPolarHBondContact CE1-CD1 3.17Å; H154-I158 WeakPolarHBondContact O-CG1 3.33Å; H154-I158 PolarHBondContact O-N 2.91Å; H154-I158 VanDerWaalsContact O-N 3.15Å; E155-I158 WeakPolarHBondContact O-CB 3.41Å; E155-I158 PolarHBondContact O-N 3.48Å; L156-I158 VanDerWaalsContact C-N 3.27Å; L156-I158 PolarHBondContact O-N 2.96Å; I158-T160 PolarHBondContact O-N 3.08Å; I158-D161 PolarHBondContact O-N 2.81Å; I158-A166 HydrophobicContact CG1-CB 3.89Å
159N86Confident88.8Confident78 Ų7847.7 Ų47.742%0.41725%0.252SS..Hα-helixtrans-69.2-13.3-176.4-67.2-14.9000113.7L116 E155 L156 D161L116-N159 HydrophobicContact CD1-CB 3.86Å; E155-N159 VanDerWaalsContact O-CG 3.29Å; E155-N159 PolarHBondContact O-N 2.9Å; E155-N159 PolarHBondContact O-ND2 2.88Å; L156-N159 PolarHBondContact O-N 3.44Å; N159-D161 VanDerWaalsContact C-N 3.35Å
160T83.3Confident88.8Confident1 Ų149.5 Ų49.51%0.00626%0.257CS..THydrogen-bonded Turntrans-93.75.5173.345.70000112.6K109 T112 L113 L116 L156 M157 I158 N162K109-T160 WeakPolarHBondContact CD-O 3.29Å; K109-T160 WeakPolarHBondContact CE-O 3.23Å; K109-T160 PolarHBondContact NZ-O 2.77Å; T112-T160 HydrophobicContact CG2-CG2 3.87Å; L113-T160 HydrophobicContact CD2-CG2 3.77Å; L113-T160 HydrophobicContact CG-CG2 4.01Å; L116-T160 HydrophobicContact CD1-CG2 4.12Å; L156-T160 WeakPolarHBondContact O-CB 3.44Å; L156-T160 WeakPolarHBondContact O-CG2 3.26Å; L156-T160 PolarHBondContact O-N 3.4Å; L156-T160 PolarHBondContact O-OG1 2.91Å; M157-T160 WeakPolarHBondContact CA-OG1 3.32Å; M157-T160 PolarHBondContact O-OG1 3.37Å; I158-T160 PolarHBondContact O-N 3.08Å; T160-N162 PolarHBondContact O-N 3.2Å
161D79.2Confident88.5Confident137 Ų13750.7 Ų50.773%0.73327%0.269SS*.THydrogen-bonded Turntrans59.123.1-174.7-62.5-47000114.2I158 N159 V163I158-D161 PolarHBondContact O-N 2.81Å; N159-D161 VanDerWaalsContact C-N 3.35Å; D161-V163 PolarHBondContact O-N 3.17Å
162N80.7Confident88.3Confident31 Ų3148.4 Ų48.417%0.16626%0.255CS..  trans-97.574.4-178-154.7-40.3000111.6M157 T160 P164 L165 A166M157-N162 PolarHBondContact O-N 3.18Å; M157-N162 VanDerWaalsContact O-N 3.11Å; T160-N162 PolarHBondContact O-N 3.2Å; N162-P164 WeakPolarHBondContact OD1-CD 3.44Å; N162-L165 HydrophobicContact CB-CB 4.18Å; N162-L165 HydrophobicContact CB-CD1 4.29Å; N162-L165 HydrophobicContact CB-CG 4.4Å; N162-L165 VanDerWaalsContact CG-CD1 3.48Å; N162-L165 VanDerWaalsContact ND2-CD1 3.27Å; N162-L165 WeakPolarHBondContact ND2-CD1 3.49Å; N162-L165 PolarHBondContact O-N 3.47Å; N162-L165 VanDerWaalsContact O-N 3.11Å; N162-L165 VanDerWaalsContact OD1-CG 3.26Å; N162-L165 WeakPolarHBondContact OD1-CG 3.5Å; N162-L165 PolarHBondContact OD1-N 2.86Å; N162-A166 PolarHBondContact O-N 2.86Å
163V81.8Confident88.1Confident90 Ų9050.2 Ų50.255%0.54526%0.263SS..Hα-helixtrans-54.3-42-176.9-178.90000113.5D161 A166 K167D161-V163 PolarHBondContact O-N 3.17Å; V163-A166 PolarHBondContact O-N 3.16Å; V163-K167 WeakPolarHBondContact O-CG 3.41Å; V163-K167 PolarHBondContact O-N 2.94Å
164P84.7Confident87.7Confident87 Ų8755.5 Ų55.557%0.56529%0.291SS*.Hα-helixtrans-62.9-40.1175.4-24.135.4000113.8N162 K167 T168N162-P164 WeakPolarHBondContact OD1-CD 3.44Å; P164-K167 PolarHBondContact O-N 3.43Å; P164-T168 PolarHBondContact O-N 3.48Å; P164-T168 PolarHBondContact O-OG1 2.93Å
165L88.3Confident87.2Confident3 Ų360.7 Ų60.72%0.01631%0.309CS..Hα-helixtrans-72.7-37.7177.7-64.2-176.1000111.9I101 D104 L105 M157 N162 K167 T168 V169I101-L165 HydrophobicContact CB-CD2 4.48Å; I101-L165 HydrophobicContact CG1-CD2 4.17Å; I101-L165 HydrophobicContact CG2-CD1 4.11Å; D104-L165 HydrophobicContact CB-CD1 4.29Å; D104-L165 HydrophobicContact CB-CD2 3.72Å; D104-L165 HydrophobicContact CB-CG 4.44Å; L105-L165 HydrophobicContact CD2-CD1 4.28Å; L105-L165 HydrophobicContact CG-CD1 3.86Å; M157-L165 HydrophobicContact CB-CB 4.48Å; M157-L165 HydrophobicContact CG-CB 4.12Å; M157-L165 HydrophobicContact SD-CB 3.64Å; M157-L165 HydrophobicContact SD-CD1 4.12Å; N162-L165 HydrophobicContact CB-CB 4.18Å; N162-L165 HydrophobicContact CB-CD1 4.29Å; N162-L165 HydrophobicContact CB-CG 4.4Å; N162-L165 VanDerWaalsContact CG-CD1 3.48Å; N162-L165 VanDerWaalsContact ND2-CD1 3.27Å; N162-L165 WeakPolarHBondContact ND2-CD1 3.49Å; N162-L165 PolarHBondContact O-N 3.47Å; N162-L165 VanDerWaalsContact O-N 3.11Å; N162-L165 VanDerWaalsContact OD1-CG 3.26Å; N162-L165 WeakPolarHBondContact OD1-CG 3.5Å; N162-L165 PolarHBondContact OD1-N 2.86Å; L165-K167 VanDerWaalsContact C-N 3.3Å; L165-K167 PolarHBondContact O-N 3.25Å; L165-T168 WeakPolarHBondContact O-CA 3.45Å; L165-T168 WeakPolarHBondContact O-CB 3.44Å; L165-T168 PolarHBondContact O-N 2.95Å; L165-V169 WeakPolarHBondContact O-CG2 3.5Å; L165-V169 PolarHBondContact O-N 3.14Å
166A89.3Confident86.4Confident8 Ų858.7 Ų58.77%0.06630%0.301CS..Hα-helixtrans-58.5-43.2171.800000111.1H154 M157 I158 N162 V163 T168 V169 K170H154-A166 PolarHBondContact CD2-O 2.85Å; H154-A166 VanDerWaalsContact CD2-O 3.22Å; M157-A166 HydrophobicContact CB-CB 3.8Å; I158-A166 HydrophobicContact CG1-CB 3.89Å; N162-A166 PolarHBondContact O-N 2.86Å; V163-A166 PolarHBondContact O-N 3.16Å; A166-T168 VanDerWaalsContact C-N 3.31Å; A166-T168 PolarHBondContact O-N 3.13Å; A166-V169 PolarHBondContact O-N 2.98Å; A166-K170 WeakPolarHBondContact O-CB 3.21Å; A166-K170 PolarHBondContact O-N 3.19Å
167K88.1Confident85.2Confident146 Ų14663.3 Ų63.364%0.63533%0.331SS*.Hα-helixtrans-62.2-37.1173-74.5178-178.8179.10112.7V163 P164 L165 K170 G171V163-K167 WeakPolarHBondContact O-CG 3.41Å; V163-K167 PolarHBondContact O-N 2.94Å; P164-K167 PolarHBondContact O-N 3.43Å; L165-K167 VanDerWaalsContact C-N 3.3Å; L165-K167 PolarHBondContact O-N 3.25Å; K167-K170 PolarHBondContact O-N 2.67Å; K167-G171 PolarHBondContact O-N 3.03Å
168T87.9Confident83.4Confident38 Ų3869.5 Ų69.523%0.23337%0.371CS..Hα-helixtrans-63-47.6176.8-61.60000110.9M97 K100 I101 P164 L165 A166 G171 Y172M97-T168 HydrophobicContact CG-CG2 4.13Å; K100-T168 HydrophobicContact CD-CG2 4.44Å; I101-T168 HydrophobicContact CG1-CG2 4.47Å; P164-T168 PolarHBondContact O-N 3.48Å; P164-T168 PolarHBondContact O-OG1 2.93Å; L165-T168 WeakPolarHBondContact O-CA 3.45Å; L165-T168 WeakPolarHBondContact O-CB 3.44Å; L165-T168 PolarHBondContact O-N 2.95Å; A166-T168 VanDerWaalsContact C-N 3.31Å; A166-T168 PolarHBondContact O-N 3.13Å; T168-G171 PolarHBondContact O-N 3.3Å; T168-Y172 PolarHBondContact O-N 3.18Å
169V91Very high81.6Confident0 Ų070.8 Ų70.80%038%0.383CS..Hα-helixtrans-66.2-41.1176.5-1750000111.4M97 I101 V150 L153 H154 M157 L165 A166 G171 Y172 K173M97-V169 HydrophobicContact SD-CB 4.45Å; M97-V169 HydrophobicContact SD-CG1 4.41Å; M97-V169 HydrophobicContact SD-CG2 4.36Å; I101-V169 HydrophobicContact CD1-CG2 3.45Å; I101-V169 VanDerWaalsContact CD1-CG2 3.45Å; V150-V169 HydrophobicContact CB-CG1 3.89Å; V150-V169 HydrophobicContact CG2-CG1 3.79Å; L153-V169 HydrophobicContact CB-CG1 4.22Å; L153-V169 HydrophobicContact CD2-CG1 4.19Å; L153-V169 HydrophobicContact CD2-CG2 3.88Å; L153-V169 HydrophobicContact CG-CG1 4.26Å; L153-V169 HydrophobicContact CG-CG2 3.92Å; H154-V169 HydrophobicContact CB-CB 4.26Å; H154-V169 HydrophobicContact CB-CG1 3.7Å; M157-V169 HydrophobicContact CG-CG2 3.77Å; L165-V169 WeakPolarHBondContact O-CG2 3.5Å; L165-V169 PolarHBondContact O-N 3.14Å; A166-V169 PolarHBondContact O-N 2.98Å; V169-G171 VanDerWaalsContact C-N 3.34Å; V169-G171 PolarHBondContact O-N 3.06Å; V169-Y172 WeakPolarHBondContact O-CB 3.36Å; V169-Y172 PolarHBondContact O-N 2.97Å; V169-K173 WeakPolarHBondContact O-CB 3.23Å; V169-K173 PolarHBondContact O-N 3.02Å
170K90Very high79.6Confident105 Ų10570 Ų7046%0.45739%0.394SS..Hα-helixtrans-60-45.5176.3-170.4175.3175.6178.90111.6A166 K167 Y172 K173 D174A166-K170 WeakPolarHBondContact O-CB 3.21Å; A166-K170 PolarHBondContact O-N 3.19Å; K167-K170 PolarHBondContact O-N 2.67Å; K170-Y172 PolarHBondContact O-N 2.9Å; K170-K173 WeakPolarHBondContact O-CB 3.31Å; K170-K173 PolarHBondContact O-N 3.43Å; K170-K173 VanDerWaalsContact O-N 3.1Å; K170-D174 WeakPolarHBondContact O-CB 3.22Å; K170-D174 VanDerWaalsContact O-CG 3.22Å; K170-D174 PolarHBondContact O-N 3.12Å
171G88.1Confident77.7Confident25 Ų2576.4 Ų76.426%0.25844%0.435SS..Hα-helixtrans-60.3-33.8177.900000112.7K167 T168 V169 R175K167-G171 PolarHBondContact O-N 3.03Å; T168-G171 PolarHBondContact O-N 3.3Å; V169-G171 VanDerWaalsContact C-N 3.34Å; V169-G171 PolarHBondContact O-N 3.06Å; G171-R175 VanDerWaalsContact C-NH1 3.34Å; G171-R175 WeakPolarHBondContact O-CG 3.37Å; G171-R175 PolarHBondContact O-NH1 2.98Å
172Y88.3Confident75.7Confident22 Ų2273.4 Ų73.49%0.08644%0.437CS..Hα-helixtrans-70.9-48.3170.7-179.7-90.8000111.6E93 Y94 M97 K147 V150 T168 V169 K170 D174 R175 L176E93-Y172 HydrophobicContact CB-CD2 4.35Å; E93-Y172 HydrophobicContact CB-CE2 3.94Å; Y94-Y172 WeakPolarHBondContact CB-OH 3.13Å; Y94-Y172 HydrophobicContact CD2-CE1 4.25Å; M97-Y172 HydrophobicContact CE-CD1 4.29Å; M97-Y172 HydrophobicContact CE-CG 4.38Å; M97-Y172 WeakPolarHBondContact SD-CB 3.45Å; M97-Y172 HydrophobicContact SD-CD1 3.91Å; M97-Y172 HydrophobicContact SD-CD2 4.16Å; M97-Y172 HydrophobicContact SD-CG 3.54Å; M97-Y172 VanDerWaalsContact SD-CG 3.54Å; K147-Y172 WeakPolarHBondContact O-CE1 3.47Å; K147-Y172 PolarHBondContact O-OH 3.42Å; V150-Y172 HydrophobicContact CB-CD1 4.47Å; V150-Y172 HydrophobicContact CG1-CD1 3.81Å; V150-Y172 HydrophobicContact CG1-CE1 3.74Å; V150-Y172 HydrophobicContact CG2-CD1 3.9Å; V150-Y172 HydrophobicContact CG2-CE1 4.44Å; T168-Y172 PolarHBondContact O-N 3.18Å; V169-Y172 WeakPolarHBondContact O-CB 3.36Å; V169-Y172 PolarHBondContact O-N 2.97Å; K170-Y172 PolarHBondContact O-N 2.9Å; Y172-D174 VanDerWaalsContact C-N 3.35Å; Y172-D174 PolarHBondContact O-N 3.19Å; Y172-R175 WeakPolarHBondContact O-CB 3.32Å; Y172-R175 PolarHBondContact O-N 3.18Å; Y172-L176 HydrophobicContact CD1-CD1 4.27Å; Y172-L176 HydrophobicContact CD1-CG 4.39Å; Y172-L176 HydrophobicContact CE1-CD1 3.91Å; Y172-L176 HydrophobicContact CE1-CD2 3.81Å; Y172-L176 HydrophobicContact CE1-CG 4.04Å; Y172-L176 PolarHBondContact O-N 3.5Å
173K88.7Confident73.4Confident76 Ų7676.2 Ų76.233%0.3347%0.473SS..Hα-helixtrans-56.3-44.3178.9-177.8176.5169165.90112.9V150 D151 V169 K170 R175 L176V150-K173 HydrophobicContact CG2-CB 3.73Å; V150-K173 HydrophobicContact CG2-CG 4.26Å; D151-K173 VanDerWaalsContact CG-NZ 3.31Å; D151-K173 VanDerWaalsContact OD1-CD 3.27Å; D151-K173 WeakPolarHBondContact OD1-CD 3.24Å; D151-K173 WeakPolarHBondContact OD1-CE 3.49Å; D151-K173 IonicContact OD1-NZ 3.86Å; D151-K173 PolarHBondContact OD1-NZ 3.47Å; D151-K173 IonicContact OD2-NZ 3.35Å; V169-K173 WeakPolarHBondContact O-CB 3.23Å; V169-K173 PolarHBondContact O-N 3.02Å; K170-K173 WeakPolarHBondContact O-CB 3.31Å; K170-K173 PolarHBondContact O-N 3.43Å; K170-K173 VanDerWaalsContact O-N 3.1Å; K173-R175 PolarHBondContact O-N 3.12Å; K173-R175 VanDerWaalsContact O-N 3.15Å; K173-L176 WeakPolarHBondContact O-CB 3.49Å; K173-L176 PolarHBondContact O-N 3.3Å
174D86.3Confident70.8Confident111 Ų11175.4 Ų75.459%0.59448%0.483SS*.THydrogen-bonded Turntrans-65.9-16.3-179.5-66.7-16000112.3K170 Y172K170-D174 WeakPolarHBondContact O-CB 3.22Å; K170-D174 VanDerWaalsContact O-CG 3.22Å; K170-D174 PolarHBondContact O-N 3.12Å; Y172-D174 VanDerWaalsContact C-N 3.35Å; Y172-D174 PolarHBondContact O-N 3.19Å
175R83.7Confident68.4Low149 Ų14977.4 Ų77.456%0.56249%0.493SS*.THydrogen-bonded Turntrans-91-12174-64.2-170.4-57.5-100.615.5113.4E93 G171 Y172 K173E93-R175 IonicContact OE2-CZ 3.84Å; E93-R175 IonicContact OE2-NE 3.91Å; E93-R175 PolarHBondContact OE2-NE 3.3Å; E93-R175 IonicContact OE2-NH2 2.66Å; E93-R175 PolarHBondContact OE2-NH2 3.05Å; G171-R175 VanDerWaalsContact C-NH1 3.34Å; G171-R175 WeakPolarHBondContact O-CG 3.37Å; G171-R175 PolarHBondContact O-NH1 2.98Å; Y172-R175 WeakPolarHBondContact O-CB 3.32Å; Y172-R175 PolarHBondContact O-N 3.18Å; K173-R175 PolarHBondContact O-N 3.12Å; K173-R175 VanDerWaalsContact O-N 3.15Å
176L76.2Confident65.4Low37 Ų3784 Ų8419%0.19453%0.528CS..SBendtrans-72.3144.8176.6-64.6175.7000110.7K147 V150 Y172 K173K147-L176 WeakPolarHBondContact O-CD2 3.25Å; V150-L176 HydrophobicContact CG2-CD1 4.32Å; Y172-L176 HydrophobicContact CD1-CD1 4.27Å; Y172-L176 HydrophobicContact CD1-CG 4.39Å; Y172-L176 HydrophobicContact CE1-CD1 3.91Å; Y172-L176 HydrophobicContact CE1-CD2 3.81Å; Y172-L176 HydrophobicContact CE1-CG 4.04Å; Y172-L176 PolarHBondContact O-N 3.5Å; K173-L176 WeakPolarHBondContact O-CB 3.49Å; K173-L176 PolarHBondContact O-N 3.3Å
177P65.8Low62.5Low99 Ų9990.5 Ų90.564%0.64356%0.562SS**PPolyproline II helixtrans-60.1144.6171.925.3-32000110.1T179P177-T179 PolarHBondContact O-N 3.31Å
178P55.1Low59.7Low130 Ų13092.9 Ų92.984%0.84458%0.575SS**PPolyproline II helixtrans-59.4118.3-177.922.4-31.5000109.9G180P178-G180 PolarHBondContact O-N 3.28Å
179T50.5Low56.9Low113 Ų11396.4 Ų96.469%0.69360%0.601SS**PPolyproline II helixtrans-65120.2170.537.60000108P177P177-T179 PolarHBondContact O-N 3.31Å
180G44Very low54.3Low62 Ų62101.3 Ų101.364%0.63964%0.642SS**PPolyproline II helixtrans-57.3150170.400000110.1P178 G182P178-G180 PolarHBondContact O-N 3.28Å; G180-G182 PolarHBondContact O-N 3.41Å
181P45Very low51.5Low135 Ų135105 Ų10588%0.87766%0.661SS**PPolyproline II helixtrans-63.1126-177.914.5-13.8000109.9
182G35.6Very low48.9Very low75 Ų75113 Ų11377%0.77369%0.691SS**PPolyproline II helixtrans-53.6145.8173.600000112G180 G184G180-G182 PolarHBondContact O-N 3.41Å; G182-G184 PolarHBondContact O-N 2.68Å
183G34.2Very low46.2Very low90 Ų90120.8 Ų120.893%0.92873%0.729SS**PPolyproline II helixtrans-53.4125.1-173.400000114.2
184G26.6Very low43.6Very low72 Ų72123.6 Ų123.674%0.74275%0.752SS**  trans-115126.2152.700000108.1G182G182-G184 PolarHBondContact O-N 2.68Å
185V33.1Very low40.9Very low130 Ų130126.3 Ų126.379%0.78876%0.763SS**  trans-56.6131179.6-176.30000110.8
186N26.8Very low38.8Very low141 Ų141124.6 Ų124.675%0.75477%0.771SS**  -179.8121.1127.9-89.8-23.4000114.1
187N27.5Very low37.1Very low144 Ų144128.5 Ų128.577%0.7780%0.802SS**  trans42.2115.5144-67.6-10.6000121.5S189N187-S189 PolarHBondContact O-N 3.48Å
188H30.6Very low36.4Very low196 Ų196129.1 Ų129.191%0.90780%0.796SS**  trans-36.8126.2157-68.1-77.9000114.3
189S29.1Very low36.3Very low113 Ų113128.5 Ų128.579%0.7979%0.786SS**  trans-139121.3132.948.70000107.9N187 Q191N187-S189 PolarHBondContact O-N 3.48Å; S189-Q191 PolarHBondContact O-N 3.08Å
190A35.5Very low36.8Very low103 Ų103130.9 Ų130.985%0.85179%0.792SS**  trans-69.5120.3179.700000109.2
191Q30.8Very low38.2Very low182 Ų182133.1 Ų133.185%0.8579%0.79SS**  trans-123.9120.8154.7-75.2-172.9-8.300108S189 E193S189-Q191 PolarHBondContact O-N 3.08Å; Q191-E193 PolarHBondContact O-N 3.39Å
192Q34.7Very low40.3Very low193 Ų193130.6 Ų130.690%0.90277%0.767SS**  trans-72.599.5-177-1591655.700106.9T194Q192-T194 PolarHBondContact O-N 3.39Å
193E31.3Very low43Very low186 Ų186128.5 Ų128.587%0.86974%0.736SS**PPolyproline II helixtrans-68.7116.4172.7-77.8-175.417100109.2Q191Q191-E193 PolarHBondContact O-N 3.39Å
194T32.7Very low45.8Very low135 Ų135125.1 Ų125.183%0.82870%0.695SS**PPolyproline II helixtrans-75.9122.6167.918.70000107.5Q192Q192-T194 PolarHBondContact O-N 3.39Å
195M29.9Very low48.8Very low168 Ų168125.4 Ų125.483%0.82869%0.686SS**PPolyproline II helixtrans-58.3131.2179.9-68-78-82.200110.5
196P39.3Very low51.6Low112 Ų112120.2 Ų120.273%0.72765%0.654SS**PPolyproline II helixtrans-67.7137.1172.528.3-31.4000109.4E198P196-E198 PolarHBondContact O-N 2.86Å; P196-E198 VanDerWaalsContact O-N 3.17Å
197S41.8Very low54.5Low119 Ų119118.6 Ų118.683%0.83265%0.649SS**  trans-59.3114.9175.354.10000110.1
198E51.2Low57.5Low112 Ų112115.9 Ų115.952%0.52363%0.632SS.*  trans-66.8136.8178.8-62.4-178.415400110.9P196 I200 R406P196-E198 PolarHBondContact O-N 2.86Å; P196-E198 VanDerWaalsContact O-N 3.17Å; E198-I200 PolarHBondContact O-N 2.82Å; E198-I200 VanDerWaalsContact O-N 3.13Å; E198-R406 IonicContact OE1-CZ 2.8Å; E198-R406 IonicContact OE1-NH1 3.64Å; E198-R406 PolarHBondContact OE1-NH1 3.46Å; E198-R406 IonicContact OE2-CZ 3.14Å; E198-R406 IonicContact OE2-NH1 2.66Å; E198-R406 PolarHBondContact OE2-NH1 3.37Å
199D53.2Low60.2Low118 Ų118113.1 Ų113.163%0.63162%0.624SS**  trans-67.3108.2175.3-156.8-12.6000108.8D201 E202D199-D201 PolarHBondContact O-N 3Å; D199-E202 PolarHBondContact O-N 3.1Å; D199-E202 VanDerWaalsContact O-N 3.09Å
200I60Low63.2Low162 Ų162110 Ų11083%0.83160%0.601SS**THydrogen-bonded Turntrans-59.1-21.8-170.4-62.5170000111.6E198E198-I200 PolarHBondContact O-N 2.82Å; E198-I200 VanDerWaalsContact O-N 3.13Å
201D74.3Confident66Low110 Ų110106.5 Ų106.559%0.58857%0.566SS**THydrogen-bonded Turntrans-88.7-8.2-177.1-154.232.3000114.5D199 F203 K440D199-D201 PolarHBondContact O-N 3Å; D201-F203 VanDerWaalsContact C-N 3.35Å; D201-F203 PolarHBondContact O-N 3.15Å; D201-K440 WeakPolarHBondContact O-CD 3.39Å; D201-K440 WeakPolarHBondContact OD1-CE 3.35Å; D201-K440 IonicContact OD1-NZ 3.32Å; D201-K440 PolarHBondContact OD1-NZ 3.04Å
202E88.2Confident69Low82 Ų8297.8 Ų97.838%0.38353%0.525SS..SBendtrans-73.4-25.4-177.2-167.8-170.9163.600112.8D199 R441D199-E202 PolarHBondContact O-N 3.1Å; D199-E202 VanDerWaalsContact O-N 3.09Å; E202-R441 HydrophobicContact CG-CG 4.39Å; E202-R441 WeakPolarHBondContact O-CB 3.35Å; E202-R441 PolarHBondContact O-N 2.85Å; E202-R441 WeakPolarHBondContact OE1-CD 3.48Å; E202-R441 IonicContact OE1-CZ 3.4Å; E202-R441 IonicContact OE1-NE 3.54Å; E202-R441 IonicContact OE1-NH1 2.88Å; E202-R441 PolarHBondContact OE1-NH1 2.68Å
203F91.6Very high71.9Confident30 Ų3088.8 Ų88.813%0.13248%0.483CS..BIsolated β-bridgetrans-121.3148.4-170.9-62.9-89.7000113.7D201 R441 V443D201-F203 VanDerWaalsContact C-N 3.35Å; D201-F203 PolarHBondContact O-N 3.15Å; F203-R441 VanDerWaalsContact CA-O 3.28Å; F203-R441 WeakPolarHBondContact CA-O 3.35Å; F203-R441 HydrophobicContact CD1-CB 3.59Å; F203-R441 HydrophobicContact CE1-CB 3.7Å; F203-R441 HydrophobicContact CG-CB 4.36Å; F203-V443 HydrophobicContact CD1-CG2 3.82Å; F203-V443 HydrophobicContact CE1-CG2 3.76Å
204Y92.8Very high75.1Confident19 Ų1979.9 Ų79.98%0.07544%0.442CS..  trans-69.7132.4165-70.3-75.9000110.6G318 P320 D366 L438 T439 K440 R441 L442Y204-G318 WeakPolarHBondContact CE1-O 3.28Å; Y204-P320 HydrophobicContact CD1-CG 4.29Å; Y204-P320 HydrophobicContact CD2-CB 4.44Å; Y204-P320 HydrophobicContact CD2-CG 4.42Å; Y204-P320 HydrophobicContact CE2-CB 4.38Å; Y204-P320 HydrophobicContact CG-CG 4.15Å; Y204-D366 HydrophobicContact CE1-CB 4.45Å; Y204-D366 WeakPolarHBondContact OH-CB 3.32Å; Y204-D366 PolarHBondContact OH-OD1 2.95Å; Y204-L438 HydrophobicContact CE2-CB 4.33Å; Y204-L438 HydrophobicContact CE2-CD2 4Å; Y204-T439 PolarHBondContact OH-N 3.34Å; Y204-T439 PolarHBondContact OH-OG1 3.5Å; Y204-K440 HydrophobicContact CD1-CB 4.25Å; Y204-K440 HydrophobicContact CD1-CD 4.37Å; Y204-K440 HydrophobicContact CD2-CB 3.71Å; Y204-K440 HydrophobicContact CE1-CB 4.21Å; Y204-K440 HydrophobicContact CE1-CG 4.39Å; Y204-K440 HydrophobicContact CE2-CB 3.68Å; Y204-K440 WeakPolarHBondContact CE2-O 3.4Å; Y204-K440 HydrophobicContact CG-CB 4.01Å; Y204-R441 PolarHBondContact N-O 3.33Å; Y204-L442 HydrophobicContact CD2-CB 3.92Å; Y204-L442 HydrophobicContact CD2-CD1 4.23Å
205S90.5Very high78.2Confident79 Ų7973.6 Ų73.655%0.55240%0.403SS*.  trans-78.9124174.4-170.80000110.6T207S205-T207 WeakPolarHBondContact OG-CG2 3.49Å; S205-T207 PolarHBondContact OG-OG1 3.45Å
206L91.1Very high81.5Confident21 Ų2165.6 Ų65.611%0.1136%0.363CS..  trans-119.960.8179.7-67-173.2000110.8R211 D278 A279 L442 L444L206-R211 PolarHBondContact O-NE 3.29Å; L206-D278 VanDerWaalsContact CA-OD2 3.28Å; L206-D278 WeakPolarHBondContact CA-OD2 3.4Å; L206-D278 HydrophobicContact CD2-CB 3.63Å; L206-A279 HydrophobicContact CD2-CB 4.27Å; L206-L442 HydrophobicContact CD1-CD1 3.86Å; L206-L442 HydrophobicContact CD2-CD1 4.3Å; L206-L442 HydrophobicContact CG-CD1 4.29Å; L206-L444 HydrophobicContact CD1-CD2 3.72Å
207T89.3Confident84.2Confident107 Ų10760.3 Ų60.366%0.65633%0.329SS*.  trans-102.3-16.1-169.148.20000114.8S205 D278S205-T207 WeakPolarHBondContact OG-CG2 3.49Å; S205-T207 PolarHBondContact OG-OG1 3.45Å; T207-D278 PolarHBondContact N-OD2 2.8Å
208Q88.8Confident86.8Confident86 Ų8654.7 Ų54.740%0.40229%0.29SS..SBendtrans-72.1153.8179.9-61.1-69.3-21.500111.2P210 R211 D278Q208-P210 CarbonylContact C-O 3.54Å; Q208-P210 WeakPolarHBondContact CB-O 3.47Å; Q208-P210 CarbonylContact O-C 3.44Å; Q208-R211 WeakPolarHBondContact O-CG 3.19Å; Q208-R211 PolarHBondContact O-N 3.19Å; Q208-D278 WeakPolarHBondContact CA-OD2 3.15Å; Q208-D278 VanDerWaalsContact CB-OD2 3.3Å; Q208-D278 WeakPolarHBondContact CB-OD2 3.42Å; Q208-D278 WeakPolarHBondContact CG-OD1 3.42Å; Q208-D278 PolarHBondContact N-OD2 3.2Å
209N87.8Confident88.9Confident139 Ų13949.3 Ų49.374%0.74327%0.265SS*.SBendtrans-134.1106.2172.8-173.110.1000109.2
210P91.5Very high90.7Very high47 Ų4745.9 Ų45.931%0.30525%0.245SC..SBendcis-70.9152.6431.3-35.9000112.9Q208 G212 G248 V250Q208-P210 CarbonylContact C-O 3.54Å; Q208-P210 WeakPolarHBondContact CB-O 3.47Å; Q208-P210 CarbonylContact O-C 3.44Å; P210-G212 PolarHBondContact O-N 3.28Å; P210-G248 WeakPolarHBondContact CA-O 3.34Å; P210-V250 HydrophobicContact CB-CG2 3.61Å; P210-V250 HydrophobicContact CG-CG2 4.01Å
211R94.8Very high92Very high29 Ų2939.9 Ų39.911%0.10922%0.215CC..  trans-68.2-21.3173.6-70.8-170.1-178.1153.3-1.9112.9L206 Q208 F247 G248 F249 D278 A279 R445L206-R211 PolarHBondContact O-NE 3.29Å; Q208-R211 WeakPolarHBondContact O-CG 3.19Å; Q208-R211 PolarHBondContact O-N 3.19Å; R211-F247 WeakPolarHBondContact CD-O 3.25Å; R211-F247 PolarHBondContact NH1-O 2.88Å; R211-G248 PolarHBondContact N-O 2.82Å; R211-F249 HydrophobicContact CB-CE2 4.33Å; R211-F249 HydrophobicContact CB-CZ 4.34Å; R211-D278 WeakPolarHBondContact O-CA 3.19Å; R211-D278 WeakPolarHBondContact O-CB 3.3Å; R211-D278 PolarHBondContact O-N 2.66Å; R211-A279 PolarHBondContact O-N 3.11Å; R211-R445 PolarHBondContact NH1-O 3.03Å; R211-R445 PolarHBondContact NH2-O 3Å
212G94.9Very high92.5Very high0 Ų034.7 Ų34.70%019%0.187CC..EExtended strand (participates in β ladder)trans156.4-173.7171.400000113.9P210 F249 V250 E277 A279P210-G212 PolarHBondContact O-N 3.28Å; G212-F249 CarbonylContact O-C 3.47Å; G212-F249 WeakPolarHBondContact O-CA 3.42Å; G212-F249 WeakPolarHBondContact O-CB 3.31Å; G212-F249 WeakPolarHBondContact O-CD1 3.37Å; G212-V250 PolarHBondContact O-N 2.65Å; G212-E277 WeakPolarHBondContact CA-OE2 3.18Å; G212-A279 WeakPolarHBondContact CA-O 3.34Å
213C95.6Very high92.1Very high3 Ų336.4 Ų36.42%0.0220%0.203CC..EExtended strand (participates in β ladder)trans-86.6142.3176.6-169.90000112.3I252 E277 L280 V281C213-I252 WeakPolarHBondContact SG-CD1 3.18Å; C213-E277 PolarHBondContact N-OE2 2.9Å; C213-E277 VanDerWaalsContact N-OE2 3.14Å; C213-L280 HydrophobicContact CB-CD1 4.49Å; C213-V281 PolarHBondContact O-N 3.39Å
214C97.9Very high91.1Very high0 Ų039.3 Ų39.30%024%0.241CC..EExtended strand (participates in β ladder)trans-119.5106.8167.8177.10000109.2F244 F249 V250 P251 I252 V281C214-F244 HydrophobicContact CB-CB 3.99Å; C214-F244 HydrophobicContact CB-CG 4.25Å; C214-F249 HydrophobicContact CB-CB 4.03Å; C214-V250 PolarHBondContact N-O 3.37Å; C214-P251 CarbonylContact O-C 3.52Å; C214-P251 WeakPolarHBondContact O-CA 3.39Å; C214-I252 PolarHBondContact O-N 2.95Å; C214-V281 CarbonylContact C-O 3.52Å; C214-V281 VanDerWaalsContact CA-O 3.32Å; C214-V281 WeakPolarHBondContact CA-O 3.19Å; C214-V281 HydrophobicContact CB-CB 4.09Å
215V98.1Very high90.4Very high2 Ų239.9 Ų39.91%0.01225%0.248CC..EExtended strand (participates in β ladder)trans-94.9125.7179.6178.10000109.6I217 I252 M265 L269 V281 V282 C283V215-I217 HydrophobicContact CG1-CG1 4.31Å; V215-I252 WeakPolarHBondContact CA-O 3.16Å; V215-M265 HydrophobicContact CG1-CE 3.82Å; V215-M265 HydrophobicContact CG1-SD 4.02Å; V215-L269 HydrophobicContact CB-CD2 4.3Å; V215-L269 HydrophobicContact CG2-CD1 4.22Å; V215-L269 HydrophobicContact CG2-CD2 3.59Å; V215-V281 PolarHBondContact N-O 3.5Å; V215-V282 CarbonylContact O-C 3.51Å; V215-V282 WeakPolarHBondContact O-CA 3.4Å; V215-C283 PolarHBondContact O-N 3.03Å
216I98.3Very high89.6Confident0 Ų043.6 Ų43.60%025%0.254CS..EExtended strand (participates in β ladder)trans-116.4111.1179.3-59.1163.1000108.4L240 I252 I253 H254 C283 L285I216-L240 HydrophobicContact CD1-CB 3.68Å; I216-L240 HydrophobicContact CG1-CB 4.36Å; I216-L240 HydrophobicContact CG2-CD1 4.37Å; I216-I252 PolarHBondContact N-O 3.14Å; I216-I253 HydrophobicContact CB-CG1 4.25Å; I216-I253 HydrophobicContact CD1-CG1 4.1Å; I216-I253 CarbonylContact O-C 3.53Å; I216-I253 WeakPolarHBondContact O-CA 3.24Å; I216-H254 PolarHBondContact O-N 2.62Å; I216-C283 CarbonylContact C-O 3.56Å; I216-C283 WeakPolarHBondContact CA-O 3.45Å; I216-C283 HydrophobicContact CG1-CB 4.12Å; I216-C283 HydrophobicContact CG2-CB 4.45Å; I216-L285 HydrophobicContact CG2-CD1 3.66Å
217I97.6Very high88.8Confident1 Ų144.4 Ų44.41%0.00526%0.256CS..EExtended strand (participates in β ladder)trans-96.9111.5173.2-51.4178.4000108V215 L257 I262 M265 L266 C283 V284 L285V215-I217 HydrophobicContact CG1-CG1 4.31Å; I217-L257 HydrophobicContact CG2-CD1 4.27Å; I217-I262 HydrophobicContact CD1-CG2 4.12Å; I217-I262 HydrophobicContact CG2-CD1 4.49Å; I217-I262 HydrophobicContact CG2-CG1 4.23Å; I217-M265 HydrophobicContact CD1-CE 3.31Å; I217-M265 HydrophobicContact CG1-CE 3.55Å; I217-L266 HydrophobicContact CD1-CD1 4.49Å; I217-L266 HydrophobicContact CD1-CD2 4.31Å; I217-L266 HydrophobicContact CD1-CG 4.45Å; I217-C283 PolarHBondContact N-O 3.31Å; I217-V284 HydrophobicContact CB-CG1 4.48Å; I217-V284 HydrophobicContact CD1-CG2 4.2Å; I217-L285 PolarHBondContact O-N 3.15Å
218S96.4Very high88.2Confident1 Ų146.9 Ų46.91%0.00725%0.254CS..EExtended strand (participates in β ladder)trans-120.499.8-175.6-161.20000111.1D237 H254 T255 N256S218-D237 WeakPolarHBondContact CB-OD1 3.38Å; S218-D237 WeakPolarHBondContact CB-OD2 3.28Å; S218-D237 VanDerWaalsContact OG-CG 3.28Å; S218-D237 PolarHBondContact OG-OD1 2.94Å; S218-D237 PolarHBondContact OG-OD2 3.07Å; S218-D237 VanDerWaalsContact OG-OD2 3.14Å; S218-H254 PolarHBondContact N-O 3.36Å; S218-T255 CarbonylContact O-C 3.58Å; S218-T255 VanDerWaalsContact O-CA 3.26Å; S218-T255 WeakPolarHBondContact O-CA 3.39Å; S218-N256 PolarHBondContact O-N 3.12Å
219N94Very high87.8Confident0 Ų047.4 Ų47.40%025%0.254CS..  trans-95.2109.7176.9-75.5-3.9000109.5F222 R230 N256 L257 L285 S286 I294 T296N219-F222 HydrophobicContact CB-CE1 4.24Å; N219-F222 HydrophobicContact CB-CE2 4.04Å; N219-F222 HydrophobicContact CB-CZ 3.49Å; N219-F222 VanDerWaalsContact CB-CZ 3.49Å; N219-F222 VanDerWaalsContact O-CE2 3.29Å; N219-F222 WeakPolarHBondContact O-CE2 3.38Å; N219-R230 WeakPolarHBondContact O-CD 3.34Å; N219-R230 PolarHBondContact O-NH1 3.31Å; N219-N256 WeakPolarHBondContact OD1-CA 2.99Å; N219-N256 PolarHBondContact OD1-N 3.28Å; N219-L257 PolarHBondContact ND2-O 2.99Å; N219-L257 PolarHBondContact OD1-N 2.71Å; N219-L257 PolarHBondContact OD1-O 3.13Å; N219-L285 PolarHBondContact N-O 3.33Å; N219-S286 WeakPolarHBondContact CB-OG 3.46Å; N219-I294 PolarHBondContact ND2-O 3.31Å; N219-T296 HydrophobicContact CB-CG2 4.1Å
220E90.3Very high87.5Confident45 Ų4541.2 Ų41.221%0.2122%0.221CC..  trans-105.2-48.2178.4169.7162158.600112F222 K229 R230 N256E220-F222 WeakPolarHBondContact O-CD2 3.45Å; E220-K229 HydrophobicContact CG-CG 4.08Å; E220-K229 CarbonylContact O-C 3.57Å; E220-K229 WeakPolarHBondContact O-CA 3.43Å; E220-K229 WeakPolarHBondContact O-CG 3.33Å; E220-K229 WeakPolarHBondContact OE1-CE 3.25Å; E220-R230 VanDerWaalsContact CG-O 3.22Å; E220-R230 WeakPolarHBondContact CG-O 3.42Å; E220-R230 PolarHBondContact O-N 2.96Å; E220-N256 WeakPolarHBondContact CA-OD1 2.97Å; E220-N256 PolarHBondContact N-OD1 3.18Å
221D88.8Confident86.7Confident37 Ų3742.9 Ų42.920%0.19823%0.227CC..  trans-97.9113.9-171.8-155.8-38.7000111.5T223 K229 N256 T296D221-T223 VanDerWaalsContact OD1-CB 3.23Å; D221-T223 WeakPolarHBondContact OD1-CB 3.46Å; D221-T223 WeakPolarHBondContact OD1-CG2 3.34Å; D221-T223 PolarHBondContact OD1-N 3.48Å; D221-T223 PolarHBondContact OD1-OG1 3.41Å; D221-K229 IonicContact OD2-NZ 3.66Å; D221-K229 PolarHBondContact OD2-NZ 3.25Å; D221-N256 PolarHBondContact N-OD1 3.08Å; D221-T296 VanDerWaalsContact O-CB 3.31Å; D221-T296 WeakPolarHBondContact O-CB 3.19Å; D221-T296 WeakPolarHBondContact O-CG2 3.37Å
222F85.3Confident85.6Confident1 Ų142.1 Ų42.10%0.00423%0.228CC..  trans-113.321.8179.5-65.9-94.9000111.5N219 E220 G224 S225 Y227 R230 S286 H287 I294 G295N219-F222 HydrophobicContact CB-CE1 4.24Å; N219-F222 HydrophobicContact CB-CE2 4.04Å; N219-F222 HydrophobicContact CB-CZ 3.49Å; N219-F222 VanDerWaalsContact CB-CZ 3.49Å; N219-F222 VanDerWaalsContact O-CE2 3.29Å; N219-F222 WeakPolarHBondContact O-CE2 3.38Å; E220-F222 WeakPolarHBondContact O-CD2 3.45Å; F222-G224 PolarHBondContact O-N 3.41Å; F222-S225 WeakPolarHBondContact CB-OG 3.16Å; F222-S225 WeakPolarHBondContact O-CB 3.13Å; F222-S225 PolarHBondContact O-N 3.21Å; F222-S225 PolarHBondContact O-OG 3.07Å; F222-Y227 WeakPolarHBondContact CB-O 3.43Å; F222-R230 HydrophobicContact CD2-CG 4.48Å; F222-R230 HydrophobicContact CE2-CG 3.93Å; F222-S286 WeakPolarHBondContact CZ-OG 3.33Å; F222-H287 AromaticContact CD2-CD2 3.71Å; F222-H287 AromaticContact CE2-CD2 3.49Å; F222-H287 VanDerWaalsContact CE2-CD2 3.49Å; F222-H287 WeakPolarHBondContact CE2-CD2 2.95Å; F222-H287 HydrophobicContact CZ-CB 4.47Å; F222-H287 AromaticContact CZ-CD2 3.63Å; F222-I294 HydrophobicContact CD1-CG2 4.44Å; F222-I294 HydrophobicContact CE1-CG2 4.1Å; F222-G295 WeakPolarHBondContact CD1-O 3.27Å; F222-G295 WeakPolarHBondContact CE1-O 3.35Å
223T78.2Confident84.9Confident117 Ų11742.1 Ų42.172%0.71823%0.228SC*.THydrogen-bonded Turntrans-53.1127177.442.90000110.7D221D221-T223 VanDerWaalsContact OD1-CB 3.23Å; D221-T223 WeakPolarHBondContact OD1-CB 3.46Å; D221-T223 WeakPolarHBondContact OD1-CG2 3.34Å; D221-T223 PolarHBondContact OD1-N 3.48Å; D221-T223 PolarHBondContact OD1-OG1 3.41Å
224G72.1Confident84.5Confident91 Ų9148.4 Ų48.494%0.93826%0.255SS*.THydrogen-bonded Turntrans95-1.3-174.300000115.1F222F222-G224 PolarHBondContact O-N 3.41Å
225S77.1Confident84.1Confident32 Ų3252 Ų5222%0.22427%0.273CS..SBendtrans-114178.1171.582.50000112.4F222 Y227F222-S225 WeakPolarHBondContact CB-OG 3.16Å; F222-S225 WeakPolarHBondContact O-CB 3.13Å; F222-S225 PolarHBondContact O-N 3.21Å; F222-S225 PolarHBondContact O-OG 3.07Å; S225-Y227 PolarHBondContact O-N 3.34Å; S225-Y227 PolarHBondContact OG-N 2.76Å; S225-Y227 VanDerWaalsContact OG-N 3.13Å
226K74.7Confident83.7Confident156 Ų15652 Ų5268%0.67827%0.272SS*.SBendtrans-72.7-11.1173.168.2179.9-177.6178.40113.8E289K226-E289 IonicContact NZ-OE1 2.87Å
227Y74.1Confident83.5Confident38 Ų3852.6 Ų52.615%0.14928%0.276CS..SBendtrans-93.8146.4-173.9-61.2-89000111.9F222 S225 H287 E289 I294F222-Y227 WeakPolarHBondContact CB-O 3.43Å; S225-Y227 PolarHBondContact O-N 3.34Å; S225-Y227 PolarHBondContact OG-N 2.76Å; S225-Y227 VanDerWaalsContact OG-N 3.13Å; Y227-H287 HydrophobicContact CD1-CB 3.91Å; Y227-H287 AromaticContact CD1-CG 3.92Å; Y227-H287 HydrophobicContact CE1-CB 4.34Å; Y227-H287 HydrophobicContact CG-CB 4.5Å; Y227-E289 PolarHBondContact OH-OE1 2.99Å; Y227-I294 HydrophobicContact CD2-CG2 3.68Å; Y227-I294 HydrophobicContact CE1-CG1 4.06Å; Y227-I294 HydrophobicContact CE1-CG2 4.46Å; Y227-I294 HydrophobicContact CE2-CB 4.46Å; Y227-I294 HydrophobicContact CE2-CD1 4.3Å; Y227-I294 HydrophobicContact CE2-CG1 4.21Å; Y227-I294 HydrophobicContact CE2-CG2 3.49Å; Y227-I294 VanDerWaalsContact CE2-CG2 3.49Å; Y227-I294 HydrophobicContact CG-CG2 4.26Å; Y227-I294 WeakPolarHBondContact OH-CD1 3.5Å
228R75.7Confident83.4Confident159 Ų15956.8 Ų56.860%0.630%0.296SS*.PPolyproline II helixtrans-79.5159.4179.5-62.3-171.2-171.8168.44.4112.2E83 H287E83-R228 WeakPolarHBondContact OE2-CD 3.46Å; E83-R228 IonicContact OE2-CZ 3.75Å; E83-R228 IonicContact OE2-NE 2.81Å; E83-R228 IonicContact OE2-NH1 3.07Å; E83-R228 PolarHBondContact OE2-NH1 2.73Å; R228-H287 PolarHBondContact O-NE2 3.34Å
229K80.9Confident83.3Confident97 Ų9759.1 Ų59.142%0.42231%0.308SS..PPolyproline II helixtrans-65.6136.3173.5-171.4165-174.4148.80111.6E220 D221 L231E220-K229 HydrophobicContact CG-CG 4.08Å; E220-K229 CarbonylContact O-C 3.57Å; E220-K229 WeakPolarHBondContact O-CA 3.43Å; E220-K229 WeakPolarHBondContact O-CG 3.33Å; E220-K229 WeakPolarHBondContact OE1-CE 3.25Å; D221-K229 IonicContact OD2-NZ 3.66Å; D221-K229 PolarHBondContact OD2-NZ 3.25Å; K229-L231 HydrophobicContact CD-CD2 4.06Å; K229-L231 HydrophobicContact CG-CD2 4.13Å; K229-L231 PolarHBondContact O-N 3.12Å
230R81.8Confident83.5Confident9 Ų959.1 Ų59.13%0.03431%0.308CS..  trans-95.875.7179.2-60.5175.962.4-113.85.4111.3N219 E220 F222 S233 L285 S286 H287 R381N219-R230 WeakPolarHBondContact O-CD 3.34Å; N219-R230 PolarHBondContact O-NH1 3.31Å; E220-R230 VanDerWaalsContact CG-O 3.22Å; E220-R230 WeakPolarHBondContact CG-O 3.42Å; E220-R230 PolarHBondContact O-N 2.96Å; F222-R230 HydrophobicContact CD2-CG 4.48Å; F222-R230 HydrophobicContact CE2-CG 3.93Å; R230-S233 PolarHBondContact O-OG 3.45Å; R230-L285 PolarHBondContact NH1-O 3.48Å; R230-S286 PolarHBondContact NE-O 3.18Å; R230-H287 WeakPolarHBondContact CG-NE2 3.27Å; R230-R381 VanDerWaalsContact C-CZ 3.44Å; R230-R381 VanDerWaalsContact C-NH2 3.26Å; R230-R381 VanDerWaalsContact CA-NH2 3.34Å; R230-R381 PolarHBondContact O-NH1 2.8Å
231L74.7Confident83.8Confident82 Ų8258.2 Ų58.243%0.42931%0.306SS..THydrogen-bonded Turntrans-62.6129177.8-61.8177.2000113.2K229 R381 T383K229-L231 HydrophobicContact CD-CD2 4.06Å; K229-L231 HydrophobicContact CG-CD2 4.13Å; K229-L231 PolarHBondContact O-N 3.12Å; L231-R381 VanDerWaalsContact N-NH2 3.17Å; L231-R381 PolarHBondContact O-NH1 2.71Å; L231-R381 PolarHBondContact O-NH2 2.74Å; L231-T383 CarbonylContact C-O 3.59Å; L231-T383 CarbonylContact O-C 3.59Å; L231-T383 VanDerWaalsContact O-CA 3.26Å; L231-T383 WeakPolarHBondContact O-CA 3.38Å
232G72Confident84.2Confident14 Ų1461 Ų6114%0.14432%0.321CS..THydrogen-bonded Turntrans102.71.818000000114.5K234 M235 T383 G386G232-K234 PolarHBondContact O-N 3.48Å; G232-M235 PolarHBondContact O-N 3.26Å; G232-T383 WeakPolarHBondContact CA-O 3.27Å; G232-T383 PolarHBondContact N-O 3.39Å; G232-T383 VanDerWaalsContact N-O 3.13Å; G232-G386 WeakPolarHBondContact O-CA 3.49Å
233S79.9Confident84.7Confident0 Ų061.2 Ų61.20%032%0.323CS..Hα-helixtrans-64.8-28.5176-53.90000111.8R230 M235 D236 D237 R381R230-S233 PolarHBondContact O-OG 3.45Å; S233-M235 VanDerWaalsContact C-N 3.27Å; S233-M235 PolarHBondContact O-N 3.01Å; S233-D236 WeakPolarHBondContact O-CB 3.39Å; S233-D236 PolarHBondContact O-N 3.03Å; S233-D236 VanDerWaalsContact O-N 3.1Å; S233-D237 VanDerWaalsContact O-CG 3.23Å; S233-D237 PolarHBondContact O-N 2.85Å; S233-R381 PolarHBondContact OG-NH1 3.23Å
234K87.3Confident85.7Confident135 Ų13555.7 Ų55.759%0.58729%0.288SS*.Hα-helixtrans-55.5-38.5173.6-170.1-179.7179.1-166.40113.7G232 D237 E238G232-K234 PolarHBondContact O-N 3.48Å; K234-D237 PolarHBondContact O-N 3.35Å; K234-E238 WeakPolarHBondContact CE-OE1 3.36Å; K234-E238 IonicContact NZ-OE1 3.2Å; K234-E238 WeakPolarHBondContact O-CG 3.26Å; K234-E238 PolarHBondContact O-N 3.21Å
235M88.1Confident86.9Confident76 Ų7658.1 Ų58.137%0.37427%0.273SS..Hα-helixtrans-68.4-38178.8-172.360.9161.200111.3G232 S233 N239 K385G232-M235 PolarHBondContact O-N 3.26Å; S233-M235 VanDerWaalsContact C-N 3.27Å; S233-M235 PolarHBondContact O-N 3.01Å; M235-N239 WeakPolarHBondContact O-CB 3.27Å; M235-N239 PolarHBondContact O-N 3.39Å; M235-N239 PolarHBondContact O-ND2 2.81Å; M235-N239 VanDerWaalsContact O-ND2 3.13Å; M235-K385 VanDerWaalsContact CG-O 3.27Å; M235-K385 WeakPolarHBondContact CG-O 3.48Å
236D91.2Very high87.8Confident0 Ų061.7 Ų61.70%028%0.282CS..Hα-helixtrans-63.6-44.1173.8-69.2-31.4000111.2S233 E238 N239 L240 L285 G386 S387 I390S233-D236 WeakPolarHBondContact O-CB 3.39Å; S233-D236 PolarHBondContact O-N 3.03Å; S233-D236 VanDerWaalsContact O-N 3.1Å; D236-E238 PolarHBondContact O-N 3.42Å; D236-N239 PolarHBondContact O-N 3.02Å; D236-L240 WeakPolarHBondContact O-CB 3.1Å; D236-L240 VanDerWaalsContact O-CG 3.32Å; D236-L240 WeakPolarHBondContact O-CG 3.42Å; D236-L240 PolarHBondContact O-N 3.22Å; D236-L285 HydrophobicContact CB-CD2 3.41Å; D236-L285 VanDerWaalsContact CB-CD2 3.41Å; D236-G386 VanDerWaalsContact OD1-CA 3.28Å; D236-G386 WeakPolarHBondContact OD1-CA 3.22Å; D236-S387 PolarHBondContact OD1-N 3.19Å; D236-S387 VanDerWaalsContact OD2-CB 3.23Å; D236-S387 WeakPolarHBondContact OD2-CB 3.17Å; D236-S387 PolarHBondContact OD2-N 3.45Å; D236-S387 PolarHBondContact OD2-OG 3.43Å; D236-I390 HydrophobicContact CB-CG2 3.97Å
237D93.6Very high88.8Confident14 Ų1454.2 Ų54.28%0.07525%0.249CC..Hα-helixtrans-59.7-46.9178.8-61.4-15.2000111.4S218 S233 K234 S241 I253S218-D237 WeakPolarHBondContact CB-OD1 3.38Å; S218-D237 WeakPolarHBondContact CB-OD2 3.28Å; S218-D237 VanDerWaalsContact OG-CG 3.28Å; S218-D237 PolarHBondContact OG-OD1 2.94Å; S218-D237 PolarHBondContact OG-OD2 3.07Å; S218-D237 VanDerWaalsContact OG-OD2 3.14Å; S233-D237 VanDerWaalsContact O-CG 3.23Å; S233-D237 PolarHBondContact O-N 2.85Å; K234-D237 PolarHBondContact O-N 3.35Å; D237-S241 WeakPolarHBondContact O-CB 3.49Å; D237-S241 PolarHBondContact O-N 2.62Å; D237-I253 HydrophobicContact CB-CD1 4.35Å
238E94.6Very high89.8Confident89 Ų8952.9 Ų52.942%0.41625%0.247SC..Hα-helixtrans-63.9-45.6177.9-73.8177.4-172.100111.5K234 D236 S241 N242K234-E238 WeakPolarHBondContact CE-OE1 3.36Å; K234-E238 IonicContact NZ-OE1 3.2Å; K234-E238 WeakPolarHBondContact O-CG 3.26Å; K234-E238 PolarHBondContact O-N 3.21Å; D236-E238 PolarHBondContact O-N 3.42Å; E238-S241 PolarHBondContact O-N 3.48Å; E238-N242 VanDerWaalsContact O-CB 3.25Å; E238-N242 WeakPolarHBondContact O-CB 3.36Å; E238-N242 PolarHBondContact O-N 3.42Å; E238-N242 PolarHBondContact O-ND2 3.03Å; E238-N242 VanDerWaalsContact O-ND2 3.09Å
239N95.1Very high90.9Very high50 Ų5045.7 Ų45.727%0.26722%0.22SC..Hα-helixtrans-63.1-49.2179.5-74.6-27.2000112M235 D236 L243M235-N239 WeakPolarHBondContact O-CB 3.27Å; M235-N239 PolarHBondContact O-N 3.39Å; M235-N239 PolarHBondContact O-ND2 2.81Å; M235-N239 VanDerWaalsContact O-ND2 3.13Å; D236-N239 PolarHBondContact O-N 3.02Å; N239-L243 WeakPolarHBondContact O-CB 3.27Å; N239-L243 PolarHBondContact O-N 3.31Å
240L97.3Very high91.7Very high0 Ų044.6 Ų44.60%022%0.221CC..Hα-helixtrans-62.4-47.4178.1-73.2168000111I216 D236 L243 F244 C283 L285 I390I216-L240 HydrophobicContact CD1-CB 3.68Å; I216-L240 HydrophobicContact CG1-CB 4.36Å; I216-L240 HydrophobicContact CG2-CD1 4.37Å; D236-L240 WeakPolarHBondContact O-CB 3.1Å; D236-L240 VanDerWaalsContact O-CG 3.32Å; D236-L240 WeakPolarHBondContact O-CG 3.42Å; D236-L240 PolarHBondContact O-N 3.22Å; L240-L243 PolarHBondContact O-N 3.08Å; L240-F244 HydrophobicContact CD2-CD2 4.36Å; L240-F244 HydrophobicContact CD2-CE2 3.91Å; L240-F244 WeakPolarHBondContact O-CB 3.33Å; L240-F244 VanDerWaalsContact O-CD2 3.29Å; L240-F244 WeakPolarHBondContact O-CD2 2.84Å; L240-F244 PolarHBondContact O-N 3.31Å; L240-C283 HydrophobicContact CD1-CB 3.99Å; L240-L285 HydrophobicContact CD1-CD1 3.95Å; L240-L285 HydrophobicContact CD1-CD2 4.24Å; L240-I390 HydrophobicContact CD1-CD1 4.35Å; L240-I390 HydrophobicContact CD1-CG2 3.88Å; L240-I390 HydrophobicContact CD2-CG2 4Å; L240-I390 HydrophobicContact CG-CG2 3.73Å
241S97.3Very high92.4Very high25 Ų2545.6 Ų45.618%0.17523%0.229CC..Hα-helixtrans-60.2-50.5-179.7-177.90000111.7D237 E238 L243 K245 P251D237-S241 WeakPolarHBondContact O-CB 3.49Å; D237-S241 PolarHBondContact O-N 2.62Å; E238-S241 PolarHBondContact O-N 3.48Å; S241-L243 PolarHBondContact O-N 2.87Å; S241-K245 WeakPolarHBondContact O-CB 3.41Å; S241-K245 PolarHBondContact O-N 3.5Å; S241-P251 VanDerWaalsContact O-CG 3.28Å; S241-P251 WeakPolarHBondContact O-CG 3.38Å; S241-P251 WeakPolarHBondContact OG-CB 3.28Å
242N96.8Very high93.5Very high95 Ų9544.9 Ų44.951%0.50823%0.225SC..Hα-helixtrans-62.9-42-179.8-72.7-30.5000112.1E238 R246E238-N242 VanDerWaalsContact O-CB 3.25Å; E238-N242 WeakPolarHBondContact O-CB 3.36Å; E238-N242 PolarHBondContact O-N 3.42Å; E238-N242 PolarHBondContact O-ND2 3.03Å; E238-N242 VanDerWaalsContact O-ND2 3.09Å; N242-R246 WeakPolarHBondContact O-CG 3.26Å; N242-R246 PolarHBondContact O-N 3.34Å; N242-R246 VanDerWaalsContact O-N 3.12Å
243L97.3Very high94.7Very high7 Ų747.7 Ų47.74%0.03724%0.236CC..Hα-helixtrans-66.4-52.4-179.6179.866.1000112N239 L240 S241 K245 R246 F247 C394 L397 E398 F446N239-L243 WeakPolarHBondContact O-CB 3.27Å; N239-L243 PolarHBondContact O-N 3.31Å; L240-L243 PolarHBondContact O-N 3.08Å; S241-L243 PolarHBondContact O-N 2.87Å; L243-K245 VanDerWaalsContact C-N 3.27Å; L243-K245 PolarHBondContact O-N 2.94Å; L243-R246 WeakPolarHBondContact O-CB 3.44Å; L243-R246 PolarHBondContact O-N 3.13Å; L243-R246 VanDerWaalsContact O-N 3.08Å; L243-F247 HydrophobicContact CD1-CD2 4.18Å; L243-F247 HydrophobicContact CD1-CE2 3.55Å; L243-F247 HydrophobicContact CD1-CZ 3.99Å; L243-F247 HydrophobicContact CD2-CE2 4.03Å; L243-F247 HydrophobicContact CG-CD2 3.92Å; L243-F247 HydrophobicContact CG-CE2 3.54Å; L243-F247 HydrophobicContact CG-CZ 4.45Å; L243-F247 WeakPolarHBondContact O-CD2 3.44Å; L243-F247 PolarHBondContact O-N 2.89Å; L243-C394 VanDerWaalsContact CD2-CA 3.5Å; L243-C394 HydrophobicContact CD2-CB 3.8Å; L243-L397 HydrophobicContact CD2-CB 3.93Å; L243-L397 HydrophobicContact CD2-CD1 3.96Å; L243-E398 HydrophobicContact CD1-CB 4.08Å; L243-F446 HydrophobicContact CD1-CE1 3.95Å; L243-F446 HydrophobicContact CD1-CZ 4.22Å
244F97.6Very high95.5Very high0 Ų050.4 Ų50.40%025%0.249CC..Hα-helixtrans-67.2-30.7-178.7-80.1-71.6000112.1C214 L240 F247 G248 F249 V281 F324 L397C214-F244 HydrophobicContact CB-CB 3.99Å; C214-F244 HydrophobicContact CB-CG 4.25Å; L240-F244 HydrophobicContact CD2-CD2 4.36Å; L240-F244 HydrophobicContact CD2-CE2 3.91Å; L240-F244 WeakPolarHBondContact O-CB 3.33Å; L240-F244 VanDerWaalsContact O-CD2 3.29Å; L240-F244 WeakPolarHBondContact O-CD2 2.84Å; L240-F244 PolarHBondContact O-N 3.31Å; F244-F247 HydrophobicContact CD1-CD2 4.18Å; F244-F247 HydrophobicContact CE1-CD2 4.45Å; F244-F247 CarbonylContact O-C 3.5Å; F244-F247 WeakPolarHBondContact O-CB 3.27Å; F244-F247 PolarHBondContact O-N 2.92Å; F244-G248 PolarHBondContact O-N 3.27Å; F244-F249 HydrophobicContact CB-CB 4.18Å; F244-F249 AromaticContact CD1-CD2 3.99Å; F244-F249 HydrophobicContact CD1-CD2 3.99Å; F244-F249 HydrophobicContact CD1-CE2 4.37Å; F244-F249 HydrophobicContact CD1-CG 4.35Å; F244-F249 WeakPolarHBondContact O-CB 3.38Å; F244-F249 PolarHBondContact O-N 3.08Å; F244-V281 HydrophobicContact CD1-CG1 4.31Å; F244-V281 HydrophobicContact CD1-CG2 4.15Å; F244-V281 HydrophobicContact CE1-CB 4.35Å; F244-V281 HydrophobicContact CE1-CG1 3.82Å; F244-V281 HydrophobicContact CE1-CG2 3.85Å; F244-V281 HydrophobicContact CE2-CG1 4.13Å; F244-V281 HydrophobicContact CZ-CG1 3.73Å; F244-F324 HydrophobicContact CZ-CD2 4.26Å; F244-F324 AromaticContact CZ-CE2 3.83Å; F244-F324 HydrophobicContact CZ-CE2 3.83Å; F244-L397 HydrophobicContact CZ-CD1 4.38Å
245K97Very high95.9Very high143 Ų14347.9 Ų47.962%0.62225%0.245SC*.Hα-helixtrans-60.7-43.8169.1-172176.5-178.91800112.3S241 L243 F247 G248 P251S241-K245 WeakPolarHBondContact O-CB 3.41Å; S241-K245 PolarHBondContact O-N 3.5Å; L243-K245 VanDerWaalsContact C-N 3.27Å; L243-K245 PolarHBondContact O-N 2.94Å; K245-F247 VanDerWaalsContact C-N 3.26Å; K245-F247 PolarHBondContact O-N 2.96Å; K245-G248 PolarHBondContact O-N 3.47Å; K245-P251 HydrophobicContact CB-CG 4.05Å
246R96.2Very high96.3Very high106 Ų10647.4 Ų47.440%0.424%0.244SC..Hα-helixtrans-65.9-29.2174.9-71.5170.764.1-171.41.2112.7N242 L243 G248 E398 F446 V447N242-R246 WeakPolarHBondContact O-CG 3.26Å; N242-R246 PolarHBondContact O-N 3.34Å; N242-R246 VanDerWaalsContact O-N 3.12Å; L243-R246 WeakPolarHBondContact O-CB 3.44Å; L243-R246 PolarHBondContact O-N 3.13Å; L243-R246 VanDerWaalsContact O-N 3.08Å; R246-G248 PolarHBondContact O-N 3.48Å; R246-E398 IonicContact CZ-OE1 3.79Å; R246-E398 IonicContact NH1-OE1 3.77Å; R246-E398 PolarHBondContact NH1-OE1 3.4Å; R246-E398 IonicContact NH1-OE2 3.75Å; R246-E398 IonicContact NH2-OE1 3.62Å; R246-E398 PolarHBondContact NH2-OE1 3.15Å; R246-F446 HydrophobicContact CB-CD1 3.56Å; R246-F446 HydrophobicContact CB-CE1 3.78Å; R246-F446 HydrophobicContact CB-CG 4.42Å; R246-F446 VanDerWaalsContact NH2-CZ 3.3Å; R246-F446 WeakPolarHBondContact O-CA 3.18Å; R246-V447 PolarHBondContact O-N 3.31Å
247F96.4Very high96.5Very high0 Ų048.5 Ų48.50%025%0.25CC..THydrogen-bonded Turntrans-74.5-1.3169.7-71-48.7000113.9R211 L243 F244 K245 F249 L397 A401 L444 R445 F446R211-F247 WeakPolarHBondContact CD-O 3.25Å; R211-F247 PolarHBondContact NH1-O 2.88Å; L243-F247 HydrophobicContact CD1-CD2 4.18Å; L243-F247 HydrophobicContact CD1-CE2 3.55Å; L243-F247 HydrophobicContact CD1-CZ 3.99Å; L243-F247 HydrophobicContact CD2-CE2 4.03Å; L243-F247 HydrophobicContact CG-CD2 3.92Å; L243-F247 HydrophobicContact CG-CE2 3.54Å; L243-F247 HydrophobicContact CG-CZ 4.45Å; L243-F247 WeakPolarHBondContact O-CD2 3.44Å; L243-F247 PolarHBondContact O-N 2.89Å; F244-F247 HydrophobicContact CD1-CD2 4.18Å; F244-F247 HydrophobicContact CE1-CD2 4.45Å; F244-F247 CarbonylContact O-C 3.5Å; F244-F247 WeakPolarHBondContact O-CB 3.27Å; F244-F247 PolarHBondContact O-N 2.92Å; K245-F247 VanDerWaalsContact C-N 3.26Å; K245-F247 PolarHBondContact O-N 2.96Å; F247-F249 HydrophobicContact CB-CD2 3.76Å; F247-F249 HydrophobicContact CB-CE2 4.01Å; F247-L397 HydrophobicContact CE2-CB 4.02Å; F247-L397 HydrophobicContact CZ-CB 4.08Å; F247-A401 HydrophobicContact CE1-CB 3.56Å; F247-A401 HydrophobicContact CZ-CB 3.94Å; F247-L444 HydrophobicContact CD1-CB 3.96Å; F247-L444 HydrophobicContact CE1-CB 3.74Å; F247-L444 HydrophobicContact CE2-CB 4.42Å; F247-L444 HydrophobicContact CG-CB 4.42Å; F247-L444 HydrophobicContact CZ-CB 4Å; F247-R445 WeakPolarHBondContact CD1-O 3.49Å; F247-F446 AromaticContact CD1-CD1 3.71Å; F247-F446 HydrophobicContact CD1-CD1 3.71Å; F247-F446 AromaticContact CD1-CE1 3.94Å; F247-F446 HydrophobicContact CD1-CE1 3.94Å; F247-F446 AromaticContact CE1-CD1 3.71Å; F247-F446 HydrophobicContact CE1-CD1 3.71Å; F247-F446 AromaticContact CE1-CE1 3.6Å; F247-F446 HydrophobicContact CE1-CE1 3.6Å; F247-F446 HydrophobicContact CE1-CZ 4.46Å; F247-F446 HydrophobicContact CE2-CE1 4.45Å; F247-F446 HydrophobicContact CG-CD1 4.43Å; F247-F446 HydrophobicContact CG-CE1 4.49Å; F247-F446 HydrophobicContact CZ-CD1 4.43Å; F247-F446 AromaticContact CZ-CE1 3.87Å; F247-F446 HydrophobicContact CZ-CE1 3.87Å
248G95.9Very high96.7Very high10 Ų1049.6 Ų49.610%0.10326%0.257CS..THydrogen-bonded Turntrans86.911.3178.100000114.8P210 R211 F244 K245 R246P210-G248 WeakPolarHBondContact CA-O 3.34Å; R211-G248 PolarHBondContact N-O 2.82Å; F244-G248 PolarHBondContact O-N 3.27Å; K245-G248 PolarHBondContact O-N 3.47Å; R246-G248 PolarHBondContact O-N 3.48Å
249F97.6Very high96.7Very high7 Ų745.5 Ų45.53%0.03124%0.238CC..EExtended strand (participates in β ladder)trans-85.6164.2171.8-66.7-98.8000111R211 G212 C214 F244 F247 P251 A279 V281 L444R211-F249 HydrophobicContact CB-CE2 4.33Å; R211-F249 HydrophobicContact CB-CZ 4.34Å; G212-F249 CarbonylContact O-C 3.47Å; G212-F249 WeakPolarHBondContact O-CA 3.42Å; G212-F249 WeakPolarHBondContact O-CB 3.31Å; G212-F249 WeakPolarHBondContact O-CD1 3.37Å; C214-F249 HydrophobicContact CB-CB 4.03Å; F244-F249 HydrophobicContact CB-CB 4.18Å; F244-F249 AromaticContact CD1-CD2 3.99Å; F244-F249 HydrophobicContact CD1-CD2 3.99Å; F244-F249 HydrophobicContact CD1-CE2 4.37Å; F244-F249 HydrophobicContact CD1-CG 4.35Å; F244-F249 WeakPolarHBondContact O-CB 3.38Å; F244-F249 PolarHBondContact O-N 3.08Å; F247-F249 HydrophobicContact CB-CD2 3.76Å; F247-F249 HydrophobicContact CB-CE2 4.01Å; F249-P251 WeakPolarHBondContact O-CD 3.43Å; F249-A279 HydrophobicContact CE1-CB 3.77Å; F249-A279 HydrophobicContact CZ-CB 3.89Å; F249-V281 HydrophobicContact CD1-CG2 4.01Å; F249-V281 HydrophobicContact CE1-CG2 3.65Å; F249-V281 HydrophobicContact CZ-CG2 4Å; F249-L444 HydrophobicContact CE2-CD2 4.18Å; F249-L444 HydrophobicContact CZ-CD2 4.47Å
250V97.5Very high96.7Very high74 Ų7448 Ų4845%0.44825%0.252SS..EExtended strand (participates in β ladder)trans-105103.3172.3-177.30000109P210 G212 C214P210-V250 HydrophobicContact CB-CG2 3.61Å; P210-V250 HydrophobicContact CG-CG2 4.01Å; G212-V250 PolarHBondContact O-N 2.65Å; C214-V250 PolarHBondContact N-O 3.37Å
251P97.1Very high96.7Very high31 Ų3153.6 Ų53.620%0.20128%0.276CS..EExtended strand (participates in β ladder)trans-70.9134.5177.6-16.530.8000112.3C214 S241 K245 F249C214-P251 CarbonylContact O-C 3.52Å; C214-P251 WeakPolarHBondContact O-CA 3.39Å; S241-P251 VanDerWaalsContact O-CG 3.28Å; S241-P251 WeakPolarHBondContact O-CG 3.38Å; S241-P251 WeakPolarHBondContact OG-CB 3.28Å; K245-P251 HydrophobicContact CB-CG 4.05Å; F249-P251 WeakPolarHBondContact O-CD 3.43Å
252I97.6Very high96.7Very high66 Ų6652.4 Ų52.434%0.33827%0.268SS..EExtended strand (participates in β ladder)trans-126.7114.4172.8-53.1-178.9000107.7C213 C214 V215 I216 H254C213-I252 WeakPolarHBondContact SG-CD1 3.18Å; C214-I252 PolarHBondContact O-N 2.95Å; V215-I252 WeakPolarHBondContact CA-O 3.16Å; I216-I252 PolarHBondContact N-O 3.14Å; I252-H254 WeakPolarHBondContact CG2-NE2 2.87Å
253I97.5Very high96.6Very high74 Ų7450 Ų5038%0.37926%0.256SS..EExtended strand (participates in β ladder)trans-100.8126.8-176.6-55.9166.3000109.4I216 D237 T255I216-I253 HydrophobicContact CB-CG1 4.25Å; I216-I253 HydrophobicContact CD1-CG1 4.1Å; I216-I253 CarbonylContact O-C 3.53Å; I216-I253 WeakPolarHBondContact O-CA 3.24Å; D237-I253 HydrophobicContact CB-CD1 4.35Å; I253-T255 HydrophobicContact CG2-CG2 4.01Å
254H97.3Very high96.5Very high56 Ų5655.6 Ų55.626%0.25928%0.282SS..EExtended strand (participates in β ladder)trans-115.2121.3170.9-63-82.1000109.6I216 S218 I252 L257I216-H254 PolarHBondContact O-N 2.62Å; S218-H254 PolarHBondContact N-O 3.36Å; I252-H254 WeakPolarHBondContact CG2-NE2 2.87Å; H254-L257 HydrophobicContact CB-CD1 3.73Å; H254-L257 HydrophobicContact CB-CD2 4.39Å; H254-L257 HydrophobicContact CB-CG 4.06Å
255T95.6Very high96.4Very high82 Ų8257 Ų5750%0.50329%0.289SS..EExtended strand (participates in β ladder)trans-105.4140.2-178.254.90000112S218 I253 L257S218-T255 CarbonylContact O-C 3.58Å; S218-T255 VanDerWaalsContact O-CA 3.26Å; S218-T255 WeakPolarHBondContact O-CA 3.39Å; I253-T255 HydrophobicContact CG2-CG2 4.01Å; T255-L257 PolarHBondContact O-N 3.01Å
256N95.4Very high96.3Very high67 Ų6750.3 Ų50.336%0.35826%0.26SS..SBendtrans55.247.8168.5-59-35.6000115.1S218 N219 E220 D221 T296S218-N256 PolarHBondContact O-N 3.12Å; N219-N256 WeakPolarHBondContact OD1-CA 2.99Å; N219-N256 PolarHBondContact OD1-N 3.28Å; E220-N256 WeakPolarHBondContact CA-OD1 2.97Å; E220-N256 PolarHBondContact N-OD1 3.18Å; D221-N256 PolarHBondContact N-OD1 3.08Å; N256-T296 VanDerWaalsContact C-CG2 3.41Å; N256-T296 VanDerWaalsContact CA-CG2 3.45Å; N256-T296 HydrophobicContact CB-CG2 3.87Å; N256-T296 PolarHBondContact O-OG1 3.34Å
257L96.4Very high96.2Very high23 Ų2350.2 Ų50.212%0.1226%0.263CS..  trans-80.3138.7177.6-60.3-171.3000112.3I217 N219 H254 T255 K261 I262 T296I217-L257 HydrophobicContact CG2-CD1 4.27Å; N219-L257 PolarHBondContact ND2-O 2.99Å; N219-L257 PolarHBondContact OD1-N 2.71Å; N219-L257 PolarHBondContact OD1-O 3.13Å; H254-L257 HydrophobicContact CB-CD1 3.73Å; H254-L257 HydrophobicContact CB-CD2 4.39Å; H254-L257 HydrophobicContact CB-CG 4.06Å; T255-L257 PolarHBondContact O-N 3.01Å; L257-K261 HydrophobicContact CB-CB 4.17Å; L257-K261 HydrophobicContact CD2-CB 4.25Å; L257-K261 HydrophobicContact CD2-CD 4.45Å; L257-I262 HydrophobicContact CB-CD1 4.38Å; L257-I262 HydrophobicContact CB-CG1 3.57Å; L257-I262 HydrophobicContact CD1-CG1 4.16Å; L257-T296 VanDerWaalsContact C-OG1 3.32Å; L257-T296 PolarHBondContact O-N 2.77Å; L257-T296 PolarHBondContact O-OG1 3.45Å
258T96.3Very high96.1Very high36 Ų3655.1 Ų55.122%0.22129%0.286CS..  trans-70.5163.1166.761.60000110.6D260 K261 I262 T296 D297T258-D260 VanDerWaalsContact C-N 3.27Å; T258-D260 PolarHBondContact O-N 3.28Å; T258-K261 PolarHBondContact O-N 3.24Å; T258-K261 VanDerWaalsContact O-N 3.11Å; T258-K261 WeakPolarHBondContact OG1-CG 3.22Å; T258-K261 PolarHBondContact OG1-N 2.99Å; T258-I262 WeakPolarHBondContact O-CG1 3.45Å; T258-I262 PolarHBondContact O-N 3.41Å; T258-T296 PolarHBondContact N-OG1 2.9Å; T258-D297 HydrophobicContact CG2-CB 4.02Å
259A95.3Very high96Very high4 Ų455.5 Ų55.53%0.03329%0.285CS..Hα-helixtrans-54.9-42.8179.600000112.9I262 T263 D297 K299 V301A259-I262 PolarHBondContact O-N 2.99Å; A259-T263 PolarHBondContact O-N 3.38Å; A259-T263 VanDerWaalsContact O-N 3.1Å; A259-T263 PolarHBondContact O-OG1 3Å; A259-D297 PolarHBondContact N-OD1 3.19Å; A259-K299 HydrophobicContact CB-CB 3.63Å; A259-V301 HydrophobicContact CB-CG2 3.52Å
260D95.9Very high95.8Very high102 Ų10256.4 Ų56.455%0.54529%0.292SS..Hα-helixtrans-64.5-42.6178.2-64.8-32.7000111.5T258 T263 E264 K299T258-D260 VanDerWaalsContact C-N 3.27Å; T258-D260 PolarHBondContact O-N 3.28Å; D260-T263 PolarHBondContact O-N 3.18Å; D260-E264 WeakPolarHBondContact O-CB 3.05Å; D260-E264 PolarHBondContact O-N 3.38Å; D260-K299 IonicContact OD2-NZ 3.85Å
261K97.2Very high95.6Very high117 Ų11759.7 Ų59.751%0.50930%0.301SS..Hα-helixtrans-68.6-36.2178.5-73.7-179.9178.3-178.80112.9L257 T258 T263 M265L257-K261 HydrophobicContact CB-CB 4.17Å; L257-K261 HydrophobicContact CD2-CB 4.25Å; L257-K261 HydrophobicContact CD2-CD 4.45Å; T258-K261 PolarHBondContact O-N 3.24Å; T258-K261 VanDerWaalsContact O-N 3.11Å; T258-K261 WeakPolarHBondContact OG1-CG 3.22Å; T258-K261 PolarHBondContact OG1-N 2.99Å; K261-T263 VanDerWaalsContact C-N 3.32Å; K261-M265 VanDerWaalsContact O-CB 3.23Å; K261-M265 WeakPolarHBondContact O-CB 3.35Å; K261-M265 PolarHBondContact O-N 3.31Å
262I96.1Very high95.4Very high1 Ų164.1 Ų64.11%0.00531%0.313CS..Hα-helixtrans-58.6-50.1172-69169.7000109I217 L257 T258 A259 M265 L266 I293 V301I217-I262 HydrophobicContact CD1-CG2 4.12Å; I217-I262 HydrophobicContact CG2-CD1 4.49Å; I217-I262 HydrophobicContact CG2-CG1 4.23Å; L257-I262 HydrophobicContact CB-CD1 4.38Å; L257-I262 HydrophobicContact CB-CG1 3.57Å; L257-I262 HydrophobicContact CD1-CG1 4.16Å; T258-I262 WeakPolarHBondContact O-CG1 3.45Å; T258-I262 PolarHBondContact O-N 3.41Å; A259-I262 PolarHBondContact O-N 2.99Å; I262-M265 PolarHBondContact O-N 2.88Å; I262-L266 HydrophobicContact CG2-CD1 3.78Å; I262-L266 WeakPolarHBondContact O-CD1 3.43Å; I262-L266 VanDerWaalsContact O-CG 3.29Å; I262-L266 WeakPolarHBondContact O-CG 2.98Å; I262-L266 PolarHBondContact O-N 3.45Å; I262-I293 HydrophobicContact CG2-CD1 4.16Å; I262-V301 HydrophobicContact CB-CG2 4.47Å; I262-V301 HydrophobicContact CG2-CG1 4.39Å; I262-V301 HydrophobicContact CG2-CG2 4.48Å
263T94.7Very high95.2Very high44 Ų4465.8 Ų65.827%0.2732%0.323SS..Hα-helixtrans-63.6-44.6-178.2-57.50000111.9A259 D260 K261 K267A259-T263 PolarHBondContact O-N 3.38Å; A259-T263 VanDerWaalsContact O-N 3.1Å; A259-T263 PolarHBondContact O-OG1 3Å; D260-T263 PolarHBondContact O-N 3.18Å; K261-T263 VanDerWaalsContact C-N 3.32Å; T263-K267 HydrophobicContact CG2-CD 4.13Å; T263-K267 WeakPolarHBondContact O-CB 3.49Å; T263-K267 VanDerWaalsContact O-CG 3.26Å; T263-K267 WeakPolarHBondContact O-CG 3.34Å; T263-K267 PolarHBondContact O-N 3.36Å
264E96Very high95Very high124 Ų12462.3 Ų62.358%0.57931%0.305SS*.Hα-helixtrans-62.1-48.1177.3-175.6179.5-168.100111.6D260 L266 K267 E268D260-E264 WeakPolarHBondContact O-CB 3.05Å; D260-E264 PolarHBondContact O-N 3.38Å; E264-L266 PolarHBondContact O-N 2.84Å; E264-K267 WeakPolarHBondContact O-CB 3.4Å; E264-K267 PolarHBondContact O-N 3.16Å; E264-E268 PolarHBondContact O-N 3.08Å
265M96.1Very high94.7Very high30 Ų3063 Ų6315%0.14832%0.316CS..Hα-helixtrans-59.9-46.1179.7-178.2-78-68.600111.7V215 I217 K261 I262 K267 E268 L269V215-M265 HydrophobicContact CG1-CE 3.82Å; V215-M265 HydrophobicContact CG1-SD 4.02Å; I217-M265 HydrophobicContact CD1-CE 3.31Å; I217-M265 HydrophobicContact CG1-CE 3.55Å; K261-M265 VanDerWaalsContact O-CB 3.23Å; K261-M265 WeakPolarHBondContact O-CB 3.35Å; K261-M265 PolarHBondContact O-N 3.31Å; I262-M265 PolarHBondContact O-N 2.88Å; M265-K267 VanDerWaalsContact C-N 3.34Å; M265-K267 PolarHBondContact O-N 3.15Å; M265-E268 PolarHBondContact O-N 2.88Å; M265-L269 WeakPolarHBondContact O-CB 3.46Å; M265-L269 PolarHBondContact O-N 2.56Å
266L94Very high94.5Very high2 Ų267.1 Ų67.11%0.0133%0.327CS..Hα-helixtrans-66.2-36.9178.7-68.2166.5000112I217 I262 E264 L269 S270 V282 L306 L309 F310I217-L266 HydrophobicContact CD1-CD1 4.49Å; I217-L266 HydrophobicContact CD1-CD2 4.31Å; I217-L266 HydrophobicContact CD1-CG 4.45Å; I262-L266 HydrophobicContact CG2-CD1 3.78Å; I262-L266 WeakPolarHBondContact O-CD1 3.43Å; I262-L266 VanDerWaalsContact O-CG 3.29Å; I262-L266 WeakPolarHBondContact O-CG 2.98Å; I262-L266 PolarHBondContact O-N 3.45Å; E264-L266 PolarHBondContact O-N 2.84Å; L266-L269 PolarHBondContact O-N 2.86Å; L266-S270 PolarHBondContact O-N 3.18Å; L266-V282 HydrophobicContact CD2-CG1 4.4Å; L266-L306 HydrophobicContact CD1-CB 4.26Å; L266-L306 HydrophobicContact CD1-CD1 3.57Å; L266-L306 HydrophobicContact CD1-CG 3.67Å; L266-L306 HydrophobicContact CD2-CG 4.47Å; L266-L309 HydrophobicContact CB-CD1 3.77Å; L266-F310 HydrophobicContact CD2-CE2 4.12Å; L266-F310 HydrophobicContact CD2-CZ 4.12Å
267K94.3Very high94.5Very high105 Ų10564.4 Ų64.446%0.45731%0.312SS..Hα-helixtrans-62.6-44.3172.8-78.6173.4179.1176.90111.4T263 E264 M265 L269 S270 K271 L309T263-K267 HydrophobicContact CG2-CD 4.13Å; T263-K267 WeakPolarHBondContact O-CB 3.49Å; T263-K267 VanDerWaalsContact O-CG 3.26Å; T263-K267 WeakPolarHBondContact O-CG 3.34Å; T263-K267 PolarHBondContact O-N 3.36Å; E264-K267 WeakPolarHBondContact O-CB 3.4Å; E264-K267 PolarHBondContact O-N 3.16Å; M265-K267 VanDerWaalsContact C-N 3.34Å; M265-K267 PolarHBondContact O-N 3.15Å; K267-L269 VanDerWaalsContact C-N 3.35Å; K267-S270 PolarHBondContact O-N 3.25Å; K267-S270 PolarHBondContact O-OG 3.16Å; K267-K271 WeakPolarHBondContact O-CG 3.05Å; K267-K271 PolarHBondContact O-N 3.13Å; K267-L309 HydrophobicContact CG-CD1 4.18Å; K267-L309 HydrophobicContact CG-CD2 3.84Å
268E94.6Very high94.3Very high102 Ų10264.1 Ų64.148%0.47731%0.311SS..Hα-helixtrans-64.8-39.9175.2-70-52.3132.600111.9E264 M265 S270 K271E264-E268 PolarHBondContact O-N 3.08Å; M265-E268 PolarHBondContact O-N 2.88Å; E268-S270 VanDerWaalsContact C-N 3.31Å; E268-S270 PolarHBondContact O-N 2.87Å; E268-K271 WeakPolarHBondContact O-CB 3.43Å; E268-K271 PolarHBondContact O-N 3.31Å; E268-K271 VanDerWaalsContact O-N 3.12Å; E268-K271 IonicContact OE1-NZ 2.68Å; E268-K271 PolarHBondContact OE1-NZ 3.11Å; E268-K271 IonicContact OE2-NZ 3.66Å
269L94.3Very high94.3Very high18 Ų1862.4 Ų62.49%0.09430%0.301CS..Hα-helixtrans-61-39.6175-173.964.4000112V215 M265 L266 K267 K271 R272 F274 L280 F310V215-L269 HydrophobicContact CB-CD2 4.3Å; V215-L269 HydrophobicContact CG2-CD1 4.22Å; V215-L269 HydrophobicContact CG2-CD2 3.59Å; M265-L269 WeakPolarHBondContact O-CB 3.46Å; M265-L269 PolarHBondContact O-N 2.56Å; L266-L269 PolarHBondContact O-N 2.86Å; K267-L269 VanDerWaalsContact C-N 3.35Å; L269-K271 PolarHBondContact O-N 2.95Å; L269-R272 VanDerWaalsContact O-CB 3.29Å; L269-R272 WeakPolarHBondContact O-CB 3.06Å; L269-R272 PolarHBondContact O-N 2.95Å; L269-R272 VanDerWaalsContact O-N 3.11Å; L269-F274 HydrophobicContact CD1-CZ 4.01Å; L269-F274 HydrophobicContact CG-CZ 4.21Å; L269-F274 WeakPolarHBondContact O-CE2 3.34Å; L269-L280 HydrophobicContact CD2-CD1 4.33Å; L269-F310 HydrophobicContact CB-CE1 4.38Å; L269-F310 HydrophobicContact CB-CZ 4.34Å; L269-F310 HydrophobicContact CD2-CE1 3.97Å; L269-F310 HydrophobicContact CD2-CZ 3.81Å; L269-F310 HydrophobicContact CG-CE1 3.99Å; L269-F310 HydrophobicContact CG-CZ 4.19Å
270S93Very high94.4Very high26 Ų2662.2 Ų62.218%0.18230%0.299CS..Hα-helixtrans-63.9-19.3177.775.20000113.9L266 K267 E268 V313L266-S270 PolarHBondContact O-N 3.18Å; K267-S270 PolarHBondContact O-N 3.25Å; K267-S270 PolarHBondContact O-OG 3.16Å; E268-S270 VanDerWaalsContact C-N 3.31Å; E268-S270 PolarHBondContact O-N 2.87Å; S270-V313 WeakPolarHBondContact O-CG2 3.48Å
271K93.3Very high94.5Very high143 Ų14357.4 Ų57.462%0.62227%0.273SS*.THydrogen-bonded Turntrans-87.5-10.5177-62.4170.9-171.2170.40113.4K267 E268 L269K267-K271 WeakPolarHBondContact O-CG 3.05Å; K267-K271 PolarHBondContact O-N 3.13Å; E268-K271 WeakPolarHBondContact O-CB 3.43Å; E268-K271 PolarHBondContact O-N 3.31Å; E268-K271 VanDerWaalsContact O-N 3.12Å; E268-K271 IonicContact OE1-NZ 2.68Å; E268-K271 PolarHBondContact OE1-NZ 3.11Å; E268-K271 IonicContact OE2-NZ 3.66Å; L269-K271 PolarHBondContact O-N 2.95Å
272R92.9Very high94.5Very high124 Ų12451.8 Ų51.847%0.46825%0.249SC..SBendtrans-68145.3179.5-179.6-176.5169.593-1.2110.3L269 F274 E277L269-R272 VanDerWaalsContact O-CB 3.29Å; L269-R272 WeakPolarHBondContact O-CB 3.06Å; L269-R272 PolarHBondContact O-N 2.95Å; L269-R272 VanDerWaalsContact O-N 3.11Å; R272-F274 HydrophobicContact CB-CD2 4.49Å; R272-F274 HydrophobicContact CB-CE2 3.84Å; R272-F274 HydrophobicContact CB-CZ 4Å; R272-F274 HydrophobicContact CG-CE2 4.33Å; R272-F274 HydrophobicContact CG-CZ 4.29Å; R272-F274 WeakPolarHBondContact O-CD2 3.29Å; R272-F274 VanDerWaalsContact O-CE2 3.28Å; R272-F274 WeakPolarHBondContact O-CE2 3.49Å; R272-E277 IonicContact CZ-OE1 3.62Å; R272-E277 IonicContact NE-OE1 3.74Å; R272-E277 PolarHBondContact NE-OE1 3.16Å; R272-E277 IonicContact NH2-OE1 2.62Å; R272-E277 PolarHBondContact NH2-OE1 3.23Å
273D92.8Very high94.6Very high102 Ų10251.8 Ų51.855%0.54525%0.249SC..  trans-81.7119.8169.1178.424.8000111S275 S315D273-S275 WeakPolarHBondContact OD1-CB 3.45Å; D273-S275 PolarHBondContact OD1-N 3.19Å; D273-S275 PolarHBondContact OD1-OG 2.93Å; D273-S315 WeakPolarHBondContact OD1-CB 3.36Å
274F92.8Very high94.7Very high0 Ų049.7 Ų49.70%024%0.236CC..  trans-100.911.7178.2-63-91.6000112.8L269 R272 K276 E277 L280 V313 S315 L316 K319L269-F274 HydrophobicContact CD1-CZ 4.01Å; L269-F274 HydrophobicContact CG-CZ 4.21Å; L269-F274 WeakPolarHBondContact O-CE2 3.34Å; R272-F274 HydrophobicContact CB-CD2 4.49Å; R272-F274 HydrophobicContact CB-CE2 3.84Å; R272-F274 HydrophobicContact CB-CZ 4Å; R272-F274 HydrophobicContact CG-CE2 4.33Å; R272-F274 HydrophobicContact CG-CZ 4.29Å; R272-F274 WeakPolarHBondContact O-CD2 3.29Å; R272-F274 VanDerWaalsContact O-CE2 3.28Å; R272-F274 WeakPolarHBondContact O-CE2 3.49Å; F274-K276 PolarHBondContact O-N 3.38Å; F274-K276 VanDerWaalsContact O-N 3.11Å; F274-E277 WeakPolarHBondContact CD1-OE2 3.08Å; F274-E277 PolarHBondContact O-N 3.49Å; F274-E277 VanDerWaalsContact O-O 3.07Å; F274-L280 HydrophobicContact CE1-CD1 4.01Å; F274-L280 HydrophobicContact CZ-CD1 4.41Å; F274-V313 HydrophobicContact CD2-CG1 3.9Å; F274-V313 HydrophobicContact CE2-CG1 4.18Å; F274-S315 PolarHBondContact N-OG 3.37Å; F274-L316 HydrophobicContact CB-CD2 3.55Å; F274-L316 HydrophobicContact CB-CG 3.84Å; F274-L316 HydrophobicContact CD1-CD2 3.92Å; F274-L316 HydrophobicContact CD1-CG 4.4Å; F274-L316 HydrophobicContact CD2-CD1 3.83Å; F274-L316 HydrophobicContact CD2-CD2 4.15Å; F274-L316 HydrophobicContact CD2-CG 3.75Å; F274-L316 HydrophobicContact CE2-CD1 3.99Å; F274-L316 HydrophobicContact CE2-CG 4.42Å; F274-L316 HydrophobicContact CG-CD1 4.11Å; F274-L316 HydrophobicContact CG-CD2 3.61Å; F274-L316 HydrophobicContact CG-CG 3.74Å; F274-L316 HydrophobicContact CZ-CD1 4.43Å; F274-K319 PolarHBondContact O-NZ 3.36Å
275S91.5Very high94.7Very high70 Ų7043.9 Ų43.949%0.4921%0.209SC..THydrogen-bonded Turntrans-58.2-30.6-173.1-63.80000113.5D273 K319D273-S275 WeakPolarHBondContact OD1-CB 3.45Å; D273-S275 PolarHBondContact OD1-N 3.19Å; D273-S275 PolarHBondContact OD1-OG 2.93Å; S275-K319 PolarHBondContact O-NZ 3.16Å
276K92.8Very high94.5Very high169 Ų16942.6 Ų42.674%0.73520%0.203SC*.THydrogen-bonded Turntrans-94.48.4178.4-60.4-177.2-179178.60114.4F274F274-K276 PolarHBondContact O-N 3.38Å; F274-K276 VanDerWaalsContact O-N 3.11Å
277E93.9Very high94.1Very high11 Ų1144.6 Ų44.65%0.05121%0.212CC..  trans-118.4148.5-180-64.2-178.9-171.400108.7G212 C213 R272 F274 K319G212-E277 WeakPolarHBondContact CA-OE2 3.18Å; C213-E277 PolarHBondContact N-OE2 2.9Å; C213-E277 VanDerWaalsContact N-OE2 3.14Å; R272-E277 IonicContact CZ-OE1 3.62Å; R272-E277 IonicContact NE-OE1 3.74Å; R272-E277 PolarHBondContact NE-OE1 3.16Å; R272-E277 IonicContact NH2-OE1 2.62Å; R272-E277 PolarHBondContact NH2-OE1 3.23Å; F274-E277 WeakPolarHBondContact CD1-OE2 3.08Å; F274-E277 PolarHBondContact O-N 3.49Å; F274-E277 VanDerWaalsContact O-O 3.07Å; E277-K319 VanDerWaalsContact O-CD 3.29Å; E277-K319 WeakPolarHBondContact O-CD 3.4Å; E277-K319 WeakPolarHBondContact O-CE 3.45Å; E277-K319 PolarHBondContact O-NZ 3.22Å
278D93.6Very high93.5Very high16 Ų1639.9 Ų39.99%0.08619%0.193CC..SBendtrans-88.4-29.6179.6-63.2-47.8000113L206 T207 Q208 R211 K319 P320L206-D278 VanDerWaalsContact CA-OD2 3.28Å; L206-D278 WeakPolarHBondContact CA-OD2 3.4Å; L206-D278 HydrophobicContact CD2-CB 3.63Å; T207-D278 PolarHBondContact N-OD2 2.8Å; Q208-D278 WeakPolarHBondContact CA-OD2 3.15Å; Q208-D278 VanDerWaalsContact CB-OD2 3.3Å; Q208-D278 WeakPolarHBondContact CB-OD2 3.42Å; Q208-D278 WeakPolarHBondContact CG-OD1 3.42Å; Q208-D278 PolarHBondContact N-OD2 3.2Å; R211-D278 WeakPolarHBondContact O-CA 3.19Å; R211-D278 WeakPolarHBondContact O-CB 3.3Å; R211-D278 PolarHBondContact O-N 2.66Å; D278-K319 VanDerWaalsContact O-CB 3.25Å; D278-K319 WeakPolarHBondContact O-CB 3.43Å; D278-K319 WeakPolarHBondContact O-CG 3.32Å; D278-P320 WeakPolarHBondContact O-CD 3.47Å
279A95.9Very high92.8Very high1 Ų136.6 Ų36.61%0.00818%0.178CC..EExtended strand (participates in β ladder)trans-153.7158.9-169.100000112.4L206 R211 G212 F249 P320L206-A279 HydrophobicContact CD2-CB 4.27Å; R211-A279 PolarHBondContact O-N 3.11Å; G212-A279 WeakPolarHBondContact CA-O 3.34Å; F249-A279 HydrophobicContact CE1-CB 3.77Å; F249-A279 HydrophobicContact CZ-CB 3.89Å; A279-P320 WeakPolarHBondContact CA-O 3.44Å; A279-P320 HydrophobicContact CB-CG 3.77Å
280L96.7Very high92.1Very high0 Ų041.1 Ų41.10%019%0.194CC..EExtended strand (participates in β ladder)trans-117.3135.6171.1172.364.2000109.6C213 L269 F274 V282 F310 L316 P320 L322C213-L280 HydrophobicContact CB-CD1 4.49Å; L269-L280 HydrophobicContact CD2-CD1 4.33Å; F274-L280 HydrophobicContact CE1-CD1 4.01Å; F274-L280 HydrophobicContact CZ-CD1 4.41Å; L280-V282 HydrophobicContact CD1-CG2 4.11Å; L280-V282 HydrophobicContact CD2-CG2 4.23Å; L280-V282 HydrophobicContact CG-CG2 4.07Å; L280-F310 HydrophobicContact CD2-CD1 3.41Å; L280-F310 VanDerWaalsContact CD2-CD1 3.41Å; L280-F310 HydrophobicContact CD2-CE1 3.64Å; L280-F310 HydrophobicContact CD2-CG 3.98Å; L280-F310 HydrophobicContact CD2-CZ 4.37Å; L280-L316 HydrophobicContact CB-CD1 4.31Å; L280-L316 HydrophobicContact CB-CD2 4.15Å; L280-L316 HydrophobicContact CD2-CD1 3.86Å; L280-P320 PolarHBondContact N-O 3.47Å; L280-L322 PolarHBondContact O-N 2.85Å
281V98.1Very high91.4Very high0 Ų041.2 Ų41.20%020%0.198CC..EExtended strand (participates in β ladder)trans-121.8132.5170.7-176.20000109.7C213 C214 V215 F244 F249 L322 F324C213-V281 PolarHBondContact O-N 3.39Å; C214-V281 CarbonylContact C-O 3.52Å; C214-V281 VanDerWaalsContact CA-O 3.32Å; C214-V281 WeakPolarHBondContact CA-O 3.19Å; C214-V281 HydrophobicContact CB-CB 4.09Å; V215-V281 PolarHBondContact N-O 3.5Å; F244-V281 HydrophobicContact CD1-CG1 4.31Å; F244-V281 HydrophobicContact CD1-CG2 4.15Å; F244-V281 HydrophobicContact CE1-CB 4.35Å; F244-V281 HydrophobicContact CE1-CG1 3.82Å; F244-V281 HydrophobicContact CE1-CG2 3.85Å; F244-V281 HydrophobicContact CE2-CG1 4.13Å; F244-V281 HydrophobicContact CZ-CG1 3.73Å; F249-V281 HydrophobicContact CD1-CG2 4.01Å; F249-V281 HydrophobicContact CE1-CG2 3.65Å; F249-V281 HydrophobicContact CZ-CG2 4Å; V281-L322 CarbonylContact C-O 3.53Å; V281-L322 WeakPolarHBondContact CA-O 3.46Å; V281-L322 HydrophobicContact CG2-CB 4.26Å; V281-L322 HydrophobicContact CG2-CD1 4.07Å; V281-L322 HydrophobicContact CG2-CG 4.36Å; V281-F324 HydrophobicContact CG1-CD2 4.09Å; V281-F324 HydrophobicContact CG1-CE2 4.13Å
282V97.8Very high91.1Very high0 Ų035.7 Ų35.70%018%0.176CC..EExtended strand (participates in β ladder)trans-130.5117.3174.3-176.80000109.3V215 L266 L280 V284 L322 F323 F324V215-V282 CarbonylContact O-C 3.51Å; V215-V282 WeakPolarHBondContact O-CA 3.4Å; L266-V282 HydrophobicContact CD2-CG1 4.4Å; L280-V282 HydrophobicContact CD1-CG2 4.11Å; L280-V282 HydrophobicContact CD2-CG2 4.23Å; L280-V282 HydrophobicContact CG-CG2 4.07Å; V282-V284 HydrophobicContact CG1-CG2 4.16Å; V282-L322 PolarHBondContact N-O 3.12Å; V282-F323 HydrophobicContact CB-CD1 3.71Å; V282-F323 HydrophobicContact CB-CE1 3.94Å; V282-F323 HydrophobicContact CG1-CD1 4.29Å; V282-F323 HydrophobicContact CG2-CD1 4.19Å; V282-F323 HydrophobicContact CG2-CE1 3.9Å; V282-F323 CarbonylContact O-C 3.46Å; V282-F323 VanDerWaalsContact O-CA 3.27Å; V282-F323 WeakPolarHBondContact O-CA 3.34Å; V282-F324 PolarHBondContact O-N 3.42Å
283C98Very high91Very high0 Ų029.8 Ų29.80%015%0.153CC..EExtended strand (participates in β ladder)trans-106.2128174.8-61.20000109.2V215 I216 I217 L240 L285 F324V215-C283 PolarHBondContact O-N 3.03Å; I216-C283 CarbonylContact C-O 3.56Å; I216-C283 WeakPolarHBondContact CA-O 3.45Å; I216-C283 HydrophobicContact CG1-CB 4.12Å; I216-C283 HydrophobicContact CG2-CB 4.45Å; I217-C283 PolarHBondContact N-O 3.31Å; L240-C283 HydrophobicContact CD1-CB 3.99Å; C283-L285 HydrophobicContact CB-CD1 4.36Å; C283-F324 CarbonylContact C-O 3.5Å; C283-F324 VanDerWaalsContact CA-O 3.31Å; C283-F324 WeakPolarHBondContact CA-O 3.32Å
284V96.5Very high90.8Very high1 Ų125 Ų251%0.00613%0.127CC..EExtended strand (participates in β ladder)trans-121.3119.5176.4-174.60000109.2I217 V282 I293 L306 F324 I325 Q326I217-V284 HydrophobicContact CB-CG1 4.48Å; I217-V284 HydrophobicContact CD1-CG2 4.2Å; V282-V284 HydrophobicContact CG1-CG2 4.16Å; V284-I293 HydrophobicContact CG1-CD1 3.77Å; V284-I293 HydrophobicContact CG1-CG2 4.17Å; V284-L306 HydrophobicContact CG2-CD1 4Å; V284-F324 PolarHBondContact N-O 2.89Å; V284-I325 HydrophobicContact CB-CD1 3.82Å; V284-I325 HydrophobicContact CG2-CD1 3.74Å; V284-Q326 PolarHBondContact O-N 2.86Å
285L95.3Very high90.8Very high1 Ų125 Ų251%0.00513%0.127CC..EExtended strand (participates in β ladder)trans-119103.3178.3-52.396.8000108.1I216 I217 N219 R230 D236 L240 C283 Q326 I390I216-L285 HydrophobicContact CG2-CD1 3.66Å; I217-L285 PolarHBondContact O-N 3.15Å; N219-L285 PolarHBondContact N-O 3.33Å; R230-L285 PolarHBondContact NH1-O 3.48Å; D236-L285 HydrophobicContact CB-CD2 3.41Å; D236-L285 VanDerWaalsContact CB-CD2 3.41Å; L240-L285 HydrophobicContact CD1-CD1 3.95Å; L240-L285 HydrophobicContact CD1-CD2 4.24Å; C283-L285 HydrophobicContact CB-CD1 4.36Å; L285-Q326 HydrophobicContact CB-CB 4.5Å; L285-Q326 HydrophobicContact CG-CB 4.29Å; L285-I390 HydrophobicContact CD2-CD1 4.37Å; L285-I390 HydrophobicContact CD2-CG1 3.86Å
286S92Very high90.8Very high4 Ų422.5 Ų22.53%0.02811%0.11CC..SBendtrans-149.9-179.3179.6-160.30000112.2N219 F222 R230 I294 Q326N219-S286 WeakPolarHBondContact CB-OG 3.46Å; F222-S286 WeakPolarHBondContact CZ-OG 3.33Å; R230-S286 PolarHBondContact NE-O 3.18Å; S286-I294 PolarHBondContact OG-O 3.45Å; S286-Q326 PolarHBondContact N-O 3.35Å; S286-Q326 VanDerWaalsContact O-O 3.11Å
287H86.3Confident90.8Very high44 Ų4417 Ų1720%0.2049%0.088CC..  trans-69.4158154.5-71.9-66000109.5F222 Y227 R228 R230 I294F222-H287 AromaticContact CD2-CD2 3.71Å; F222-H287 AromaticContact CE2-CD2 3.49Å; F222-H287 VanDerWaalsContact CE2-CD2 3.49Å; F222-H287 WeakPolarHBondContact CE2-CD2 2.95Å; F222-H287 HydrophobicContact CZ-CB 4.47Å; F222-H287 AromaticContact CZ-CD2 3.63Å; Y227-H287 HydrophobicContact CD1-CB 3.91Å; Y227-H287 AromaticContact CD1-CG 3.92Å; Y227-H287 HydrophobicContact CE1-CB 4.34Å; Y227-H287 HydrophobicContact CG-CB 4.5Å; R228-H287 PolarHBondContact O-NE2 3.34Å; R230-H287 WeakPolarHBondContact CG-NE2 3.27Å; H287-I294 HydrophobicContact CB-CB 4.05Å; H287-I294 HydrophobicContact CB-CG1 4.24Å; H287-I294 PolarHBondContact O-N 2.96Å
288G82Confident90.4Very high6 Ų617.4 Ų17.46%0.06210%0.095CC..EExtended strand (participates in β ladder)trans-163.3169.5177.800000112.1I292 C328G288-I292 WeakPolarHBondContact CA-O 3.37Å; G288-C328 CarbonylContact C-O 3.52Å; G288-C328 VanDerWaalsContact C-O 3.29Å; G288-C328 WeakPolarHBondContact O-CB 3.22Å
289E78.4Confident90.3Very high32 Ų3221.9 Ų21.915%0.1511%0.114CC..EExtended strand (participates in β ladder)trans-133.5178.6174.7-61.9179.4-163.400106.8K226 Y227 G291 I292 C328 Q329 V332K226-E289 IonicContact NZ-OE1 2.87Å; Y227-E289 PolarHBondContact OH-OE1 2.99Å; E289-G291 PolarHBondContact O-N 3.44Å; E289-I292 HydrophobicContact CB-CB 4.44Å; E289-I292 PolarHBondContact N-O 3.34Å; E289-I292 PolarHBondContact O-N 3Å; E289-I292 VanDerWaalsContact O-O 3.05Å; E289-C328 PolarHBondContact N-O 3.43Å; E289-Q329 PolarHBondContact O-NE2 3.1Å; E289-V332 HydrophobicContact CG-CG2 4.22Å; E289-V332 WeakPolarHBondContact OE1-CG2 3.45Å; E289-V332 VanDerWaalsContact OE2-CG2 3.3Å; E289-V332 WeakPolarHBondContact OE2-CG2 3.47Å
290R81.1Confident90Very high114 Ų11427.1 Ų27.143%0.4314%0.138SC..THydrogen-bonded Turntrans-53.2114.2-179.2-167.6-178.274.5-154.9-11111.6I292 D330 E331 Y376R290-I292 VanDerWaalsContact C-N 3.26Å; R290-I292 PolarHBondContact O-N 3.27Å; R290-D330 PolarHBondContact N-O 3.45Å; R290-E331 IonicContact CZ-OE1 3.38Å; R290-E331 IonicContact NH1-OE1 3.46Å; R290-E331 PolarHBondContact NH1-OE1 2.93Å; R290-E331 IonicContact NH2-OE1 2.88Å; R290-Y376 VanDerWaalsContact NH1-CE1 3.29Å; R290-Y376 PolarHBondContact NH1-OH 3.27Å
291G78.3Confident89.8Confident27 Ų2727.5 Ų27.528%0.27814%0.141SC..THydrogen-bonded Turntrans73.37.5179.700000115.9E289 L303E289-G291 PolarHBondContact O-N 3.44Å; G291-L303 PolarHBondContact O-N 2.83Å
292I85.6Confident89.5Confident28 Ų2833.4 Ų33.414%0.14417%0.166CC..EExtended strand (participates in β ladder)trans-132.4141.2-169.2-64.3167.6000110.8G288 E289 R290 I294 E300 V301G288-I292 WeakPolarHBondContact CA-O 3.37Å; E289-I292 HydrophobicContact CB-CB 4.44Å; E289-I292 PolarHBondContact N-O 3.34Å; E289-I292 PolarHBondContact O-N 3Å; E289-I292 VanDerWaalsContact O-O 3.05Å; R290-I292 VanDerWaalsContact C-N 3.26Å; R290-I292 PolarHBondContact O-N 3.27Å; I292-I294 HydrophobicContact CG2-CD1 4.04Å; I292-E300 HydrophobicContact CG2-CB 3.56Å; I292-E300 HydrophobicContact CG2-CG 3.75Å; I292-V301 WeakPolarHBondContact CA-O 3.44Å
293I90.9Very high89Confident0 Ų033.6 Ų33.60%017%0.168CC..EExtended strand (participates in β ladder)trans-109.5148.9164.464.4179000109.7I262 V284 V301 L303 L306 I325 A327I262-I293 HydrophobicContact CG2-CD1 4.16Å; V284-I293 HydrophobicContact CG1-CD1 3.77Å; V284-I293 HydrophobicContact CG1-CG2 4.17Å; I293-V301 HydrophobicContact CD1-CB 4.17Å; I293-V301 HydrophobicContact CD1-CG1 4.29Å; I293-V301 HydrophobicContact CG1-CB 3.68Å; I293-V301 HydrophobicContact CG1-CG1 4.26Å; I293-V301 WeakPolarHBondContact CG1-O 3.44Å; I293-V301 PolarHBondContact N-O 2.89Å; I293-V301 PolarHBondContact O-N 3.17Å; I293-L303 HydrophobicContact CG2-CD2 3.65Å; I293-L303 HydrophobicContact CG2-CG 4.12Å; I293-L306 HydrophobicContact CD1-CD1 4.38Å; I293-I325 HydrophobicContact CG2-CG2 4.34Å; I293-A327 HydrophobicContact CG2-CB 4.28Å
294I89.1Confident88.5Confident0 Ų038.6 Ų38.60%019%0.194CC..EExtended strand (participates in β ladder)trans-103.4131.8-176.6-59-61000110.4N219 F222 Y227 S286 H287 I292 K299 E300N219-I294 PolarHBondContact ND2-O 3.31Å; F222-I294 HydrophobicContact CD1-CG2 4.44Å; F222-I294 HydrophobicContact CE1-CG2 4.1Å; Y227-I294 HydrophobicContact CD2-CG2 3.68Å; Y227-I294 HydrophobicContact CE1-CG1 4.06Å; Y227-I294 HydrophobicContact CE1-CG2 4.46Å; Y227-I294 HydrophobicContact CE2-CB 4.46Å; Y227-I294 HydrophobicContact CE2-CD1 4.3Å; Y227-I294 HydrophobicContact CE2-CG1 4.21Å; Y227-I294 HydrophobicContact CE2-CG2 3.49Å; Y227-I294 VanDerWaalsContact CE2-CG2 3.49Å; Y227-I294 HydrophobicContact CG-CG2 4.26Å; Y227-I294 WeakPolarHBondContact OH-CD1 3.5Å; S286-I294 PolarHBondContact OG-O 3.45Å; H287-I294 HydrophobicContact CB-CB 4.05Å; H287-I294 HydrophobicContact CB-CG1 4.24Å; H287-I294 PolarHBondContact O-N 2.96Å; I292-I294 HydrophobicContact CG2-CD1 4.04Å; I294-K299 WeakPolarHBondContact CA-O 3.49Å; I294-E300 HydrophobicContact CD1-CG 3.79Å
295G93Very high88.1Confident0 Ų043.1 Ų43.10%022%0.218CC..  trans-75.8163.8169.300000112.2F222 D297 G298 K299F222-G295 WeakPolarHBondContact CD1-O 3.27Å; F222-G295 WeakPolarHBondContact CE1-O 3.35Å; G295-D297 PolarHBondContact O-N 3.46Å; G295-D297 VanDerWaalsContact O-N 3.13Å; G295-G298 WeakPolarHBondContact O-CA 3.49Å; G295-G298 PolarHBondContact O-N 2.9Å; G295-K299 PolarHBondContact N-O 3.02Å
296T92.3Very high87.8Confident19 Ų1943.2 Ų43.212%0.11722%0.219CC..THydrogen-bonded Turntrans-62.2-20.7178.251.50000114.2N219 D221 N256 L257 T258 G298N219-T296 HydrophobicContact CB-CG2 4.1Å; D221-T296 VanDerWaalsContact O-CB 3.31Å; D221-T296 WeakPolarHBondContact O-CB 3.19Å; D221-T296 WeakPolarHBondContact O-CG2 3.37Å; N256-T296 VanDerWaalsContact C-CG2 3.41Å; N256-T296 VanDerWaalsContact CA-CG2 3.45Å; N256-T296 HydrophobicContact CB-CG2 3.87Å; N256-T296 PolarHBondContact O-OG1 3.34Å; L257-T296 VanDerWaalsContact C-OG1 3.32Å; L257-T296 PolarHBondContact O-N 2.77Å; L257-T296 PolarHBondContact O-OG1 3.45Å; T258-T296 PolarHBondContact N-OG1 2.9Å; T296-G298 PolarHBondContact O-N 2.93Å
297D91.1Very high87.6Confident52 Ų5243.9 Ų43.928%0.27822%0.221SC..THydrogen-bonded Turntrans-78.51.4171.359.2-23.5000113.9T258 A259 G295 K299T258-D297 HydrophobicContact CG2-CB 4.02Å; A259-D297 PolarHBondContact N-OD1 3.19Å; G295-D297 PolarHBondContact O-N 3.46Å; G295-D297 VanDerWaalsContact O-N 3.13Å; D297-K299 PolarHBondContact O-N 3.31Å; D297-K299 VanDerWaalsContact OD2-CD 3.26Å; D297-K299 WeakPolarHBondContact OD2-CD 3.4Å; D297-K299 WeakPolarHBondContact OD2-CG 3.37Å; D297-K299 IonicContact OD2-NZ 2.71Å
298G86.4Confident87.7Confident20 Ų2045.1 Ų45.121%0.20623%0.23CC..SBendtrans755.9-178.500000114.4G295 T296G295-G298 WeakPolarHBondContact O-CA 3.49Å; G295-G298 PolarHBondContact O-N 2.9Å; T296-G298 PolarHBondContact O-N 2.93Å
299K91.4Very high88.1Confident111 Ų11147 Ų4748%0.48324%0.238SC..  trans-85.5158.8176.4-65.6-172.5-164.8164.90111.6A259 D260 I294 G295 D297A259-K299 HydrophobicContact CB-CB 3.63Å; D260-K299 IonicContact OD2-NZ 3.85Å; I294-K299 WeakPolarHBondContact CA-O 3.49Å; G295-K299 PolarHBondContact N-O 3.02Å; D297-K299 PolarHBondContact O-N 3.31Å; D297-K299 VanDerWaalsContact OD2-CD 3.26Å; D297-K299 WeakPolarHBondContact OD2-CD 3.4Å; D297-K299 WeakPolarHBondContact OD2-CG 3.37Å; D297-K299 IonicContact OD2-NZ 2.71Å
300E90.8Very high88.5Confident110 Ų11045.5 Ų45.551%0.51423%0.231SC..EExtended strand (participates in β ladder)trans-94.7141.6-172.1-63.4173.6-168.100112.2I292 I294I292-E300 HydrophobicContact CG2-CB 3.56Å; I292-E300 HydrophobicContact CG2-CG 3.75Å; I294-E300 HydrophobicContact CD1-CG 3.79Å
301V91.9Very high88.8Confident9 Ų942.8 Ų42.86%0.05522%0.222CC..EExtended strand (participates in β ladder)trans-125.5123.3167.6-177.40000107.9A259 I262 I292 I293A259-V301 HydrophobicContact CB-CG2 3.52Å; I262-V301 HydrophobicContact CB-CG2 4.47Å; I262-V301 HydrophobicContact CG2-CG1 4.39Å; I262-V301 HydrophobicContact CG2-CG2 4.48Å; I292-V301 WeakPolarHBondContact CA-O 3.44Å; I293-V301 HydrophobicContact CD1-CB 4.17Å; I293-V301 HydrophobicContact CD1-CG1 4.29Å; I293-V301 HydrophobicContact CG1-CB 3.68Å; I293-V301 HydrophobicContact CG1-CG1 4.26Å; I293-V301 WeakPolarHBondContact CG1-O 3.44Å; I293-V301 PolarHBondContact N-O 2.89Å; I293-V301 PolarHBondContact O-N 3.17Å
302K90.8Very high88.9Confident123 Ų12346.6 Ų46.654%0.53524%0.236SC..EExtended strand (participates in β ladder)trans-71.6134.4177.8-65.1-175178.2-175.90110.7D304 N305 L306K302-D304 VanDerWaalsContact C-N 3.32Å; K302-D304 PolarHBondContact O-N 2.85Å; K302-N305 HydrophobicContact CB-CB 4.41Å; K302-N305 PolarHBondContact O-N 3.17Å; K302-L306 PolarHBondContact O-N 2.83Å
303L88.4Confident89.1Confident5 Ų545.5 Ų45.53%0.02623%0.231CC..Hα-helixtrans-64.8-35.8176.6-76.9171000112.3G291 I293 N305 L306 F307 I325 M371G291-L303 PolarHBondContact O-N 2.83Å; I293-L303 HydrophobicContact CG2-CD2 3.65Å; I293-L303 HydrophobicContact CG2-CG 4.12Å; L303-N305 VanDerWaalsContact C-N 3.29Å; L303-N305 PolarHBondContact O-N 3.43Å; L303-L306 WeakPolarHBondContact O-CA 3.48Å; L303-L306 VanDerWaalsContact O-CB 3.27Å; L303-L306 WeakPolarHBondContact O-CB 3.24Å; L303-L306 PolarHBondContact O-N 3.21Å; L303-F307 HydrophobicContact CB-CE2 3.8Å; L303-F307 HydrophobicContact CB-CZ 4.08Å; L303-F307 HydrophobicContact CD2-CZ 4.21Å; L303-F307 WeakPolarHBondContact O-CD2 3.44Å; L303-F307 WeakPolarHBondContact O-CG 3.49Å; L303-F307 PolarHBondContact O-N 2.84Å; L303-I325 HydrophobicContact CD1-CG2 4.29Å; L303-I325 HydrophobicContact CD2-CD1 4.18Å; L303-I325 HydrophobicContact CD2-CG1 4.27Å; L303-I325 HydrophobicContact CD2-CG2 4Å; L303-M371 HydrophobicContact CD1-CE 3.69Å; L303-M371 HydrophobicContact CD1-SD 4.27Å
304D87.5Confident89Confident104 Ų10450.1 Ų50.156%0.55626%0.261SS*.Hα-helixtrans-59-42.8177.5-62.4-25.8000111.5K302 L306 F307 D308K302-D304 VanDerWaalsContact C-N 3.32Å; K302-D304 PolarHBondContact O-N 2.85Å; D304-L306 PolarHBondContact O-N 3.28Å; D304-F307 PolarHBondContact O-N 3.34Å; D304-F307 VanDerWaalsContact O-N 3.16Å; D304-D308 WeakPolarHBondContact O-CB 3.43Å; D304-D308 VanDerWaalsContact O-CG 3.24Å; D304-D308 PolarHBondContact O-N 2.98Å
305N86.9Confident89Confident96 Ų9651 Ų5151%0.51327%0.267SS..Hα-helixtrans-60.6-32.8175.2-66.90.8000112.1K302 L303 L309K302-N305 HydrophobicContact CB-CB 4.41Å; K302-N305 PolarHBondContact O-N 3.17Å; L303-N305 VanDerWaalsContact C-N 3.29Å; L303-N305 PolarHBondContact O-N 3.43Å; N305-L309 VanDerWaalsContact O-CG 3.31Å; N305-L309 WeakPolarHBondContact O-CG 3.39Å
306L89Confident88.9Confident3 Ų351 Ų512%0.01627%0.267CS..Hα-helixtrans-69.6-46.3176.9-179.6157.4000110.5L266 V284 I293 K302 L303 D304 F310 F323L266-L306 HydrophobicContact CD1-CB 4.26Å; L266-L306 HydrophobicContact CD1-CD1 3.57Å; L266-L306 HydrophobicContact CD1-CG 3.67Å; L266-L306 HydrophobicContact CD2-CG 4.47Å; V284-L306 HydrophobicContact CG2-CD1 4Å; I293-L306 HydrophobicContact CD1-CD1 4.38Å; K302-L306 PolarHBondContact O-N 2.83Å; L303-L306 WeakPolarHBondContact O-CA 3.48Å; L303-L306 VanDerWaalsContact O-CB 3.27Å; L303-L306 WeakPolarHBondContact O-CB 3.24Å; L303-L306 PolarHBondContact O-N 3.21Å; D304-L306 PolarHBondContact O-N 3.28Å; L306-F310 VanDerWaalsContact O-CD2 3.26Å; L306-F310 WeakPolarHBondContact O-CD2 3.22Å; L306-F323 HydrophobicContact CD2-CD1 3.44Å; L306-F323 VanDerWaalsContact CD2-CD1 3.44Å; L306-F323 HydrophobicContact CD2-CE1 3.43Å; L306-F323 VanDerWaalsContact CD2-CE1 3.43Å; L306-F323 HydrophobicContact CD2-CG 4.49Å; L306-F323 HydrophobicContact CD2-CZ 4.47Å
307F88.9Confident88.8Confident18 Ų1853.1 Ų53.18%0.07928%0.275CS..Hα-helixtrans-68.7-40.7-178.8-53.8-42.7000112.1L303 D304 L309 F310 K311 F323 I325 I369L303-F307 HydrophobicContact CB-CE2 3.8Å; L303-F307 HydrophobicContact CB-CZ 4.08Å; L303-F307 HydrophobicContact CD2-CZ 4.21Å; L303-F307 WeakPolarHBondContact O-CD2 3.44Å; L303-F307 WeakPolarHBondContact O-CG 3.49Å; L303-F307 PolarHBondContact O-N 2.84Å; D304-F307 PolarHBondContact O-N 3.34Å; D304-F307 VanDerWaalsContact O-N 3.16Å; F307-L309 PolarHBondContact O-N 3.2Å; F307-F310 PolarHBondContact O-N 3.4Å; F307-F310 VanDerWaalsContact O-N 3.08Å; F307-K311 PolarHBondContact O-N 3.05Å; F307-F323 HydrophobicContact CD1-CB 4.43Å; F307-F323 AromaticContact CD1-CD1 3.95Å; F307-F323 HydrophobicContact CD1-CD1 3.95Å; F307-F323 HydrophobicContact CD1-CD2 4.04Å; F307-F323 HydrophobicContact CD1-CE1 4.2Å; F307-F323 HydrophobicContact CD1-CE2 4.27Å; F307-F323 AromaticContact CD1-CG 3.87Å; F307-F323 HydrophobicContact CD1-CG 3.87Å; F307-F323 HydrophobicContact CD1-CZ 4.36Å; F307-F323 HydrophobicContact CE1-CB 3.84Å; F307-F323 AromaticContact CE1-CD1 3.98Å; F307-F323 HydrophobicContact CE1-CD1 3.98Å; F307-F323 HydrophobicContact CE1-CD2 4.28Å; F307-F323 AromaticContact CE1-CG 3.77Å; F307-F323 HydrophobicContact CE1-CG 3.77Å; F307-I325 HydrophobicContact CZ-CG1 4.48Å; F307-I369 HydrophobicContact CD1-CD1 4.13Å; F307-I369 HydrophobicContact CD1-CG1 4.26Å; F307-I369 HydrophobicContact CD2-CD1 3.78Å; F307-I369 HydrophobicContact CE1-CD1 3.99Å; F307-I369 HydrophobicContact CE1-CG1 3.9Å; F307-I369 HydrophobicContact CE1-CG2 4.22Å; F307-I369 HydrophobicContact CE2-CD1 3.61Å; F307-I369 HydrophobicContact CE2-CG1 4.35Å; F307-I369 HydrophobicContact CE2-CG2 4.45Å; F307-I369 HydrophobicContact CG-CD1 4.05Å; F307-I369 HydrophobicContact CZ-CD1 3.72Å; F307-I369 HydrophobicContact CZ-CG1 3.95Å; F307-I369 HydrophobicContact CZ-CG2 3.74Å
308D87.9Confident88.6Confident71 Ų7152.1 Ų52.138%0.3828%0.277SS..Hα-helixtrans-62.6-29.9-177.1-74.4-18.9000113.3D304 F310 K311D304-D308 WeakPolarHBondContact O-CB 3.43Å; D304-D308 VanDerWaalsContact O-CG 3.24Å; D304-D308 PolarHBondContact O-N 2.98Å; D308-F310 PolarHBondContact O-N 2.82Å; D308-K311 PolarHBondContact O-N 2.86Å; D308-K311 WeakPolarHBondContact OD1-CD 3.48Å; D308-K311 VanDerWaalsContact OD1-CE 3.23Å; D308-K311 WeakPolarHBondContact OD1-CE 3.25Å; D308-K311 IonicContact OD1-NZ 3.82Å; D308-K311 PolarHBondContact OD1-NZ 3.11Å
309L89.5Confident88.9Confident44 Ų4453.1 Ų53.123%0.2328%0.275CS..Hα-helixtrans-58.8-31175.4-73.7169.2000112.7L266 K267 N305 F307 V313L266-L309 HydrophobicContact CB-CD1 3.77Å; K267-L309 HydrophobicContact CG-CD1 4.18Å; K267-L309 HydrophobicContact CG-CD2 3.84Å; N305-L309 VanDerWaalsContact O-CG 3.31Å; N305-L309 WeakPolarHBondContact O-CG 3.39Å; F307-L309 PolarHBondContact O-N 3.2Å; L309-V313 WeakPolarHBondContact O-CG2 3.48Å
310F88.8Confident89.2Confident1 Ų147.9 Ų47.90%0.00425%0.253CS..Hα-helixtrans-99.6-8.1-175-60.5-76.7000114L266 L269 L280 L306 F307 D308 N312 V313 L316 K321 F323L266-F310 HydrophobicContact CD2-CE2 4.12Å; L266-F310 HydrophobicContact CD2-CZ 4.12Å; L269-F310 HydrophobicContact CB-CE1 4.38Å; L269-F310 HydrophobicContact CB-CZ 4.34Å; L269-F310 HydrophobicContact CD2-CE1 3.97Å; L269-F310 HydrophobicContact CD2-CZ 3.81Å; L269-F310 HydrophobicContact CG-CE1 3.99Å; L269-F310 HydrophobicContact CG-CZ 4.19Å; L280-F310 HydrophobicContact CD2-CD1 3.41Å; L280-F310 VanDerWaalsContact CD2-CD1 3.41Å; L280-F310 HydrophobicContact CD2-CE1 3.64Å; L280-F310 HydrophobicContact CD2-CG 3.98Å; L280-F310 HydrophobicContact CD2-CZ 4.37Å; L306-F310 VanDerWaalsContact O-CD2 3.26Å; L306-F310 WeakPolarHBondContact O-CD2 3.22Å; F307-F310 PolarHBondContact O-N 3.4Å; F307-F310 VanDerWaalsContact O-N 3.08Å; D308-F310 PolarHBondContact O-N 2.82Å; F310-N312 VanDerWaalsContact C-N 3.29Å; F310-N312 PolarHBondContact O-N 3.29Å; F310-V313 HydrophobicContact CD1-CG2 4.38Å; F310-L316 HydrophobicContact CD1-CD1 4.3Å; F310-K321 HydrophobicContact CB-CD 4.46Å; F310-F323 HydrophobicContact CB-CZ 4.14Å; F310-F323 AromaticContact CD2-CE1 3.83Å; F310-F323 HydrophobicContact CD2-CE1 3.83Å; F310-F323 AromaticContact CD2-CZ 3.69Å; F310-F323 HydrophobicContact CD2-CZ 3.69Å; F310-F323 HydrophobicContact CE2-CE1 4.19Å; F310-F323 HydrophobicContact CE2-CZ 4.47Å; F310-F323 HydrophobicContact CG-CZ 4.1Å
311K85.6Confident89.4Confident57 Ų5742.9 Ų42.925%0.24823%0.229CC..Hα-helixtrans-67.3-30.3173.5-70179178.7171.60112.8F307 D308 F317 D364 I367F307-K311 PolarHBondContact O-N 3.05Å; D308-K311 PolarHBondContact O-N 2.86Å; D308-K311 WeakPolarHBondContact OD1-CD 3.48Å; D308-K311 VanDerWaalsContact OD1-CE 3.23Å; D308-K311 WeakPolarHBondContact OD1-CE 3.25Å; D308-K311 IonicContact OD1-NZ 3.82Å; D308-K311 PolarHBondContact OD1-NZ 3.11Å; K311-F317 WeakPolarHBondContact O-CE1 3.25Å; K311-D364 WeakPolarHBondContact CD-OD1 3.24Å; K311-D364 IonicContact NZ-OD1 3.28Å; K311-I367 HydrophobicContact CG-CD1 3.91Å
312N82.3Confident89.7Confident107 Ų10742.5 Ų42.557%0.57223%0.227SC*.THydrogen-bonded Turntrans-109.124.3-173.9-67.4-58.3000113.6F310 P314F310-N312 VanDerWaalsContact C-N 3.29Å; F310-N312 PolarHBondContact O-N 3.29Å; N312-P314 VanDerWaalsContact O-CD 3.31Å; N312-P314 WeakPolarHBondContact O-CD 3.24Å
313V88.9Confident90Very high6 Ų636.7 Ų36.74%0.03620%0.202CC..  trans-95104.4176.5-179.70000109.1S270 F274 L309 F310 S315 L316S270-V313 WeakPolarHBondContact O-CG2 3.48Å; F274-V313 HydrophobicContact CD2-CG1 3.9Å; F274-V313 HydrophobicContact CE2-CG1 4.18Å; L309-V313 WeakPolarHBondContact O-CG2 3.48Å; F310-V313 HydrophobicContact CD1-CG2 4.38Å; V313-S315 VanDerWaalsContact C-N 3.29Å; V313-S315 PolarHBondContact O-N 3.15Å; V313-L316 HydrophobicContact CB-CB 4.32Å; V313-L316 HydrophobicContact CB-CD1 4.06Å; V313-L316 HydrophobicContact CB-CG 4.4Å; V313-L316 HydrophobicContact CG1-CB 4.29Å; V313-L316 HydrophobicContact CG1-CD1 3.9Å; V313-L316 HydrophobicContact CG1-CG 3.99Å; V313-L316 PolarHBondContact O-N 3.24Å
314P87.8Confident90.5Very high96 Ų9636.4 Ų36.462%0.62320%0.2SC*.G310 helixtrans-60.9-34.9-169.7-25.436.1000113.9N312 L316 F317N312-P314 VanDerWaalsContact O-CD 3.31Å; N312-P314 WeakPolarHBondContact O-CD 3.24Å; P314-L316 PolarHBondContact O-N 2.99Å; P314-L316 VanDerWaalsContact O-N 3.14Å; P314-F317 HydrophobicContact CB-CD2 4.49Å; P314-F317 HydrophobicContact CB-CE2 4.19Å; P314-F317 WeakPolarHBondContact O-CG 3.4Å; P314-F317 PolarHBondContact O-N 3.24Å
315S90.3Very high90.8Very high20 Ų2031.5 Ų31.514%0.1417%0.174CC..G310 helixtrans-69.1-7.517957.30000114.4D273 F274 V313 K319D273-S315 WeakPolarHBondContact OD1-CB 3.36Å; F274-S315 PolarHBondContact N-OG 3.37Å; V313-S315 VanDerWaalsContact C-N 3.29Å; V313-S315 PolarHBondContact O-N 3.15Å; S315-K319 WeakPolarHBondContact O-CD 3.47Å; S315-K319 PolarHBondContact O-NZ 3.43Å
316L90Very high91.2Very high0 Ų027.2 Ų27.20%015%0.151CC..G310 helixtrans-107.94.9176.6-71.3175.4000113.6F274 L280 F310 V313 P314 K319 K321F274-L316 HydrophobicContact CB-CD2 3.55Å; F274-L316 HydrophobicContact CB-CG 3.84Å; F274-L316 HydrophobicContact CD1-CD2 3.92Å; F274-L316 HydrophobicContact CD1-CG 4.4Å; F274-L316 HydrophobicContact CD2-CD1 3.83Å; F274-L316 HydrophobicContact CD2-CD2 4.15Å; F274-L316 HydrophobicContact CD2-CG 3.75Å; F274-L316 HydrophobicContact CE2-CD1 3.99Å; F274-L316 HydrophobicContact CE2-CG 4.42Å; F274-L316 HydrophobicContact CG-CD1 4.11Å; F274-L316 HydrophobicContact CG-CD2 3.61Å; F274-L316 HydrophobicContact CG-CG 3.74Å; F274-L316 HydrophobicContact CZ-CD1 4.43Å; L280-L316 HydrophobicContact CB-CD1 4.31Å; L280-L316 HydrophobicContact CB-CD2 4.15Å; L280-L316 HydrophobicContact CD2-CD1 3.86Å; F310-L316 HydrophobicContact CD1-CD1 4.3Å; V313-L316 HydrophobicContact CB-CB 4.32Å; V313-L316 HydrophobicContact CB-CD1 4.06Å; V313-L316 HydrophobicContact CB-CG 4.4Å; V313-L316 HydrophobicContact CG1-CB 4.29Å; V313-L316 HydrophobicContact CG1-CD1 3.9Å; V313-L316 HydrophobicContact CG1-CG 3.99Å; V313-L316 PolarHBondContact O-N 3.24Å; P314-L316 PolarHBondContact O-N 2.99Å; P314-L316 VanDerWaalsContact O-N 3.14Å; L316-K319 HydrophobicContact CD2-CB 4.45Å; L316-K319 HydrophobicContact CD2-CD 4.46Å; L316-K319 PolarHBondContact O-N 3.01Å; L316-K321 HydrophobicContact CB-CD 4.26Å; L316-K321 HydrophobicContact CD1-CD 4.5Å; L316-K321 HydrophobicContact CD1-CG 4.38Å; L316-K321 PolarHBondContact O-NZ 3.15Å
317F90.4Very high91.1Very high63 Ų6327.1 Ų27.128%0.27615%0.15SC..THydrogen-bonded Turntrans-66134.1173.9-66.2-15.7000111K311 P314 K319 K363K311-F317 WeakPolarHBondContact O-CE1 3.25Å; P314-F317 HydrophobicContact CB-CD2 4.49Å; P314-F317 HydrophobicContact CB-CE2 4.19Å; P314-F317 WeakPolarHBondContact O-CG 3.4Å; P314-F317 PolarHBondContact O-N 3.24Å; F317-K319 PolarHBondContact O-N 2.99Å; F317-K363 HydrophobicContact CE1-CG 4.44Å; F317-K363 HydrophobicContact CZ-CG 4.24Å
318G87.6Confident90.6Very high31 Ų3127.6 Ų27.632%0.3216%0.156SC..THydrogen-bonded Turntrans73.82.2-175.700000114.7Y204 D366Y204-G318 WeakPolarHBondContact CE1-O 3.28Å; G318-D366 WeakPolarHBondContact CA-OD2 3.1Å; G318-D366 PolarHBondContact N-OD2 3.42Å; G318-D366 VanDerWaalsContact N-OD2 3.16Å
319K93.4Very high89.9Confident40 Ų4024.8 Ų24.817%0.17414%0.14CC..SBendtrans-110.3138-177.1-68-178.3-173.7172.70111.2F274 S275 E277 D278 S315 L316 F317 K321 D366F274-K319 PolarHBondContact O-NZ 3.36Å; S275-K319 PolarHBondContact O-NZ 3.16Å; E277-K319 VanDerWaalsContact O-CD 3.29Å; E277-K319 WeakPolarHBondContact O-CD 3.4Å; E277-K319 WeakPolarHBondContact O-CE 3.45Å; E277-K319 PolarHBondContact O-NZ 3.22Å; D278-K319 VanDerWaalsContact O-CB 3.25Å; D278-K319 WeakPolarHBondContact O-CB 3.43Å; D278-K319 WeakPolarHBondContact O-CG 3.32Å; S315-K319 WeakPolarHBondContact O-CD 3.47Å; S315-K319 PolarHBondContact O-NZ 3.43Å; L316-K319 HydrophobicContact CD2-CB 4.45Å; L316-K319 HydrophobicContact CD2-CD 4.46Å; L316-K319 PolarHBondContact O-N 3.01Å; F317-K319 PolarHBondContact O-N 2.99Å; K319-K321 PolarHBondContact O-N 2.99Å; K319-K321 PolarHBondContact O-NZ 2.94Å; K319-D366 VanDerWaalsContact O-CB 3.31Å; K319-D366 WeakPolarHBondContact O-CB 3.4Å
320P96Very high89Confident2 Ų224.8 Ų24.81%0.01314%0.141CC..  trans-67.9131.9-17927.2-33.6000111.7Y204 D278 A279 L280 L322 D366 L438 L442Y204-P320 HydrophobicContact CD1-CG 4.29Å; Y204-P320 HydrophobicContact CD2-CB 4.44Å; Y204-P320 HydrophobicContact CD2-CG 4.42Å; Y204-P320 HydrophobicContact CE2-CB 4.38Å; Y204-P320 HydrophobicContact CG-CG 4.15Å; D278-P320 WeakPolarHBondContact O-CD 3.47Å; A279-P320 WeakPolarHBondContact CA-O 3.44Å; A279-P320 HydrophobicContact CB-CG 3.77Å; L280-P320 PolarHBondContact N-O 3.47Å; P320-L322 HydrophobicContact CB-CD2 4.15Å; P320-D366 CarbonylContact C-O 3.58Å; P320-D366 WeakPolarHBondContact CA-O 3.49Å; P320-L438 HydrophobicContact CB-CD2 4.09Å; P320-L442 HydrophobicContact CB-CD1 4.42Å; P320-L442 HydrophobicContact CB-CD2 4.01Å; P320-L442 HydrophobicContact CG-CD1 3.97Å; P320-L442 HydrophobicContact CG-CD2 4.36Å
321K96.4Very high87.3Confident5 Ų530.2 Ų30.22%0.02217%0.166CC..EExtended strand (participates in β ladder)trans-116.6104178.4-65.5159.9-76.8-760108.1F310 L316 K319 F323 G365 D366 I367 L368F310-K321 HydrophobicContact CB-CD 4.46Å; L316-K321 HydrophobicContact CB-CD 4.26Å; L316-K321 HydrophobicContact CD1-CD 4.5Å; L316-K321 HydrophobicContact CD1-CG 4.38Å; L316-K321 PolarHBondContact O-NZ 3.15Å; K319-K321 PolarHBondContact O-N 2.99Å; K319-K321 PolarHBondContact O-NZ 2.94Å; K321-F323 HydrophobicContact CB-CE2 3.96Å; K321-G365 VanDerWaalsContact CE-O 3.27Å; K321-G365 WeakPolarHBondContact CE-O 3.46Å; K321-G365 PolarHBondContact NZ-O 3.5Å; K321-D366 PolarHBondContact N-O 3.3Å; K321-I367 HydrophobicContact CB-CG1 4.2Å; K321-I367 HydrophobicContact CD-CG1 4.19Å; K321-I367 WeakPolarHBondContact O-CA 3.39Å; K321-L368 PolarHBondContact O-N 3.19Å
322L97.6Very high85.7Confident1 Ų131 Ų311%0.00518%0.176CC..EExtended strand (participates in β ladder)trans-102.7126.6-172.8-43.6-176.1000110.3L280 V281 V282 P320 F324 L368 L442L280-L322 PolarHBondContact O-N 2.85Å; V281-L322 CarbonylContact C-O 3.53Å; V281-L322 WeakPolarHBondContact CA-O 3.46Å; V281-L322 HydrophobicContact CG2-CB 4.26Å; V281-L322 HydrophobicContact CG2-CD1 4.07Å; V281-L322 HydrophobicContact CG2-CG 4.36Å; V282-L322 PolarHBondContact N-O 3.12Å; P320-L322 HydrophobicContact CB-CD2 4.15Å; L322-F324 HydrophobicContact CB-CE2 3.95Å; L322-F324 HydrophobicContact CB-CZ 4.28Å; L322-F324 HydrophobicContact CD1-CE2 4.37Å; L322-F324 HydrophobicContact CD1-CZ 4.44Å; L322-L368 CarbonylContact C-O 3.5Å; L322-L368 WeakPolarHBondContact CA-O 3.31Å; L322-L368 HydrophobicContact CD2-CB 3.72Å; L322-L368 HydrophobicContact CD2-CD2 3.82Å; L322-L368 HydrophobicContact CD2-CG 4.37Å; L322-L442 HydrophobicContact CD1-CD2 3.82Å; L322-L442 HydrophobicContact CD2-CD2 3.63Å; L322-L442 HydrophobicContact CG-CD2 4.28Å
323F97.5Very high83.6Confident0 Ų030.9 Ų30.90%018%0.18CC..EExtended strand (participates in β ladder)trans-119.4121.4177-60.8-88.3000109.3V282 L306 F307 F310 K321 I325 I367 L368 I369 G370V282-F323 HydrophobicContact CB-CD1 3.71Å; V282-F323 HydrophobicContact CB-CE1 3.94Å; V282-F323 HydrophobicContact CG1-CD1 4.29Å; V282-F323 HydrophobicContact CG2-CD1 4.19Å; V282-F323 HydrophobicContact CG2-CE1 3.9Å; V282-F323 CarbonylContact O-C 3.46Å; V282-F323 VanDerWaalsContact O-CA 3.27Å; V282-F323 WeakPolarHBondContact O-CA 3.34Å; L306-F323 HydrophobicContact CD2-CD1 3.44Å; L306-F323 VanDerWaalsContact CD2-CD1 3.44Å; L306-F323 HydrophobicContact CD2-CE1 3.43Å; L306-F323 VanDerWaalsContact CD2-CE1 3.43Å; L306-F323 HydrophobicContact CD2-CG 4.49Å; L306-F323 HydrophobicContact CD2-CZ 4.47Å; F307-F323 HydrophobicContact CD1-CB 4.43Å; F307-F323 AromaticContact CD1-CD1 3.95Å; F307-F323 HydrophobicContact CD1-CD1 3.95Å; F307-F323 HydrophobicContact CD1-CD2 4.04Å; F307-F323 HydrophobicContact CD1-CE1 4.2Å; F307-F323 HydrophobicContact CD1-CE2 4.27Å; F307-F323 AromaticContact CD1-CG 3.87Å; F307-F323 HydrophobicContact CD1-CG 3.87Å; F307-F323 HydrophobicContact CD1-CZ 4.36Å; F307-F323 HydrophobicContact CE1-CB 3.84Å; F307-F323 AromaticContact CE1-CD1 3.98Å; F307-F323 HydrophobicContact CE1-CD1 3.98Å; F307-F323 HydrophobicContact CE1-CD2 4.28Å; F307-F323 AromaticContact CE1-CG 3.77Å; F307-F323 HydrophobicContact CE1-CG 3.77Å; F310-F323 HydrophobicContact CB-CZ 4.14Å; F310-F323 AromaticContact CD2-CE1 3.83Å; F310-F323 HydrophobicContact CD2-CE1 3.83Å; F310-F323 AromaticContact CD2-CZ 3.69Å; F310-F323 HydrophobicContact CD2-CZ 3.69Å; F310-F323 HydrophobicContact CE2-CE1 4.19Å; F310-F323 HydrophobicContact CE2-CZ 4.47Å; F310-F323 HydrophobicContact CG-CZ 4.1Å; K321-F323 HydrophobicContact CB-CE2 3.96Å; F323-I325 HydrophobicContact CB-CD1 4.37Å; F323-I367 HydrophobicContact CD2-CG2 3.96Å; F323-I367 HydrophobicContact CE2-CG2 3.99Å; F323-L368 PolarHBondContact N-O 3.15Å; F323-I369 HydrophobicContact CB-CG1 4.29Å; F323-I369 HydrophobicContact CD2-CG1 4.32Å; F323-I369 CarbonylContact O-C 3.29Å; F323-I369 WeakPolarHBondContact O-CA 3.44Å; F323-G370 PolarHBondContact O-N 3.47Å
324F97.6Very high81.1Confident0 Ų039.2 Ų39.20%022%0.224CC..EExtended strand (participates in β ladder)trans-115.8111175.6-61.4-68.1000109.4F244 V281 V282 C283 V284 L322 G370 L393 L413F244-F324 HydrophobicContact CZ-CD2 4.26Å; F244-F324 AromaticContact CZ-CE2 3.83Å; F244-F324 HydrophobicContact CZ-CE2 3.83Å; V281-F324 HydrophobicContact CG1-CD2 4.09Å; V281-F324 HydrophobicContact CG1-CE2 4.13Å; V282-F324 PolarHBondContact O-N 3.42Å; C283-F324 CarbonylContact C-O 3.5Å; C283-F324 VanDerWaalsContact CA-O 3.31Å; C283-F324 WeakPolarHBondContact CA-O 3.32Å; V284-F324 PolarHBondContact N-O 2.89Å; L322-F324 HydrophobicContact CB-CE2 3.95Å; L322-F324 HydrophobicContact CB-CZ 4.28Å; L322-F324 HydrophobicContact CD1-CE2 4.37Å; L322-F324 HydrophobicContact CD1-CZ 4.44Å; F324-G370 WeakPolarHBondContact CA-O 3.35Å; F324-L393 HydrophobicContact CB-CD2 4.09Å; F324-L393 HydrophobicContact CD1-CD1 4.29Å; F324-L393 HydrophobicContact CD1-CD2 3.55Å; F324-L393 HydrophobicContact CD2-CD2 4.28Å; F324-L393 HydrophobicContact CE1-CD1 3.97Å; F324-L393 HydrophobicContact CE1-CD2 4Å; F324-L393 HydrophobicContact CG-CD2 3.7Å; F324-L393 HydrophobicContact CZ-CD1 4.49Å; F324-L413 HydrophobicContact CE1-CD2 4.24Å
325I95.2Very high78.5Confident0 Ų040.6 Ų40.60%023%0.231CC..EExtended strand (participates in β ladder)trans-113.5107.4-168.9-49.2-59.5000109.8V284 I293 L303 F307 F323 A327 G370 M371 A372V284-I325 HydrophobicContact CB-CD1 3.82Å; V284-I325 HydrophobicContact CG2-CD1 3.74Å; I293-I325 HydrophobicContact CG2-CG2 4.34Å; L303-I325 HydrophobicContact CD1-CG2 4.29Å; L303-I325 HydrophobicContact CD2-CD1 4.18Å; L303-I325 HydrophobicContact CD2-CG1 4.27Å; L303-I325 HydrophobicContact CD2-CG2 4Å; F307-I325 HydrophobicContact CZ-CG1 4.48Å; F323-I325 HydrophobicContact CB-CD1 4.37Å; I325-A327 HydrophobicContact CG2-CB 4.15Å; I325-G370 PolarHBondContact N-O 2.94Å; I325-M371 HydrophobicContact CB-CE 4.13Å; I325-M371 HydrophobicContact CB-SD 3.62Å; I325-M371 HydrophobicContact CG1-SD 3.83Å; I325-M371 HydrophobicContact CG2-CE 3.94Å; I325-M371 HydrophobicContact CG2-SD 4.05Å; I325-A372 WeakPolarHBondContact O-CB 3.44Å; I325-A372 PolarHBondContact O-N 2.73Å
326Q93.8Very high76.3Confident6 Ų644 Ų443%0.02826%0.26CS..EExtended strand (participates in β ladder)trans-96.192170172.559.640.900109.3V284 L285 S286 A379 S387 I390V284-Q326 PolarHBondContact O-N 2.86Å; L285-Q326 HydrophobicContact CB-CB 4.5Å; L285-Q326 HydrophobicContact CG-CB 4.29Å; S286-Q326 PolarHBondContact N-O 3.35Å; S286-Q326 VanDerWaalsContact O-O 3.11Å; Q326-A379 VanDerWaalsContact NE2-CB 3.28Å; Q326-S387 WeakPolarHBondContact CG-OG 3.5Å; Q326-I390 HydrophobicContact CB-CD1 4.22Å; Q326-I390 HydrophobicContact CB-CG1 4.13Å; Q326-I390 HydrophobicContact CG-CG1 4.4Å
327A87.7Confident73.7Confident1 Ų150.6 Ų50.61%0.00830%0.301CS..  trans-152.7152.2175.700000110.2I293 I325I293-A327 HydrophobicContact CG2-CB 4.28Å; I325-A327 HydrophobicContact CG2-CB 4.15Å
328C79.4Confident71.1Confident28 Ų2855.9 Ų55.919%0.18933%0.326CS..  trans-67.6157.3171.9-65.40000110.8G288 E289 D330G288-C328 CarbonylContact C-O 3.52Å; G288-C328 VanDerWaalsContact C-O 3.29Å; G288-C328 WeakPolarHBondContact O-CB 3.22Å; E289-C328 PolarHBondContact N-O 3.43Å; C328-D330 WeakPolarHBondContact CB-OD1 3.36Å
329Q73.3Confident68.6Low12 Ų1264 Ų646%0.05635%0.353CS..  trans-130.123.4178.7-67.1-63.6-65.200111.8E289 M371 T373 Y376 S377E289-Q329 PolarHBondContact O-NE2 3.1Å; Q329-M371 HydrophobicContact CG-CE 4.05Å; Q329-T373 HydrophobicContact CB-CG2 4.07Å; Q329-T373 HydrophobicContact CG-CG2 4.02Å; Q329-Y376 VanDerWaalsContact O-CA 3.27Å; Q329-Y376 WeakPolarHBondContact O-CA 3.21Å; Q329-Y376 PolarHBondContact O-N 3.29Å; Q329-S377 CarbonylContact C-O 3.34Å; Q329-S377 PolarHBondContact N-O 3Å
330D69.4Low65.6Low45 Ų4568.2 Ų68.224%0.24138%0.382CS..PPolyproline II helixtrans-79.8161.2176.753.3-14.5000112.5R290 C328 S377 K378R290-D330 PolarHBondContact N-O 3.45Å; C328-D330 WeakPolarHBondContact CB-OD1 3.36Å; D330-S377 PolarHBondContact N-O 3.04Å; D330-K378 WeakPolarHBondContact OD2-CE 3.35Å
331E53.7Low62.8Low114 Ų11475 Ų7553%0.53342%0.418SS..PPolyproline II helixtrans-91.1138.7169.3-70.7-172.5164.400109.3R290 Y376R290-E331 IonicContact CZ-OE1 3.38Å; R290-E331 IonicContact NH1-OE1 3.46Å; R290-E331 PolarHBondContact NH1-OE1 2.93Å; R290-E331 IonicContact NH2-OE1 2.88Å; E331-Y376 HydrophobicContact CG-CD1 4.17Å; E331-Y376 HydrophobicContact CG-CE1 4.16Å
332V51Low59.8Low75 Ų7583.1 Ų83.146%0.45546%0.456SS..PPolyproline II helixtrans-67.8134.5173.5-170.10000109.1E289 L334E289-V332 HydrophobicContact CG-CG2 4.22Å; E289-V332 WeakPolarHBondContact OE1-CG2 3.45Å; E289-V332 VanDerWaalsContact OE2-CG2 3.3Å; E289-V332 WeakPolarHBondContact OE2-CG2 3.47Å; V332-L334 PolarHBondContact O-N 3.25Å; V332-L334 VanDerWaalsContact O-N 3.1Å
333P38Very low57Low103 Ų10391 Ų9167%0.66950%0.498SS*.PPolyproline II helixtrans-59.5118.7165.7-16.128.2000108.2T335P333-T335 PolarHBondContact O-N 3.35Å
334L37.7Very low53.9Low181 Ų18199.3 Ų99.395%0.94854%0.537SS*.  trans-58.682.8175.8-71.9162.4000110.8V332V332-L334 PolarHBondContact O-N 3.25Å; V332-L334 VanDerWaalsContact O-N 3.1Å
335T33.5Very low50.9Low126 Ų126108.1 Ų108.177%0.77358%0.578SS**  trans-96.399.5164.652.90000108.6P333P333-T335 PolarHBondContact O-N 3.35Å
336A43.8Very low47.8Very low92 Ų92113.4 Ų113.476%0.7662%0.615SS**SBendtrans54.183.4153.800000117.9
337T34Very low44.8Very low138 Ų138122.2 Ų122.285%0.84765%0.653SS**  -160.3113.5127.63.70000111.3
338Q36.3Very low41.9Very low174 Ų174131.1 Ų131.181%0.81370%0.695SS**  trans38.7103.6157-61.3-175.95.900118.9T340Q338-T340 PolarHBondContact O-N 2.98Å; Q338-T340 VanDerWaalsContact O-N 3.17Å
339K35.9Very low39.4Very low201 Ų201135.7 Ų135.787%0.87472%0.722SS**  trans-50.2116150.8-69180175.9-177.20109.3
340T29.9Very low37.3Very low129 Ų129141.1 Ų141.179%0.79176%0.758SS**  trans-116.2117.9147.338.60000106.7Q338Q338-T340 PolarHBondContact O-N 2.98Å; Q338-T340 VanDerWaalsContact O-N 3.17Å
341N37.4Very low35.4Very low144 Ų144144.6 Ų144.677%0.7779%0.787SS**  trans-60.2137.8173.7-60-36.3000108.7
342Q33.1Very low34.1Very low176 Ų176146.6 Ų146.682%0.82280%0.801SS**  trans-163.2114.1134.3-105.7162.136.100109.3
343D38.1Very low33.5Very low166 Ų166148 Ų14889%0.88881%0.814SS**  trans-60.4123.5159.9-66.7-52.2000108.3
344E33.9Very low33Very low175 Ų175149.6 Ų149.682%0.81882%0.821SS**  trans-131.5113.8157.2-75.2-160.6162.400111
345Q34.2Very low32.7Very low184 Ų184150.7 Ų150.786%0.8682%0.819SS**  trans-83.7102.3179.4-166.7173.45200107.4K347Q345-K347 PolarHBondContact O-N 3.32Å
346S30.2Very low32.5Very low112 Ų112149.9 Ų149.978%0.78382%0.819SS**  trans-78.8105.8176.9570000110.3
347K30Very low31.9Very low190 Ų190151.5 Ų151.583%0.82681%0.814SS**PPolyproline II helixtrans-68.5122.7163.1-71177.3175.4176.40109.3Q345Q345-K347 PolarHBondContact O-N 3.32Å
348E26.8Very low31.9Very low188 Ų188150 Ų15088%0.87982%0.816SS**PPolyproline II helixtrans-92.7120.2163.1-70.8-174.6173.500109.4
349T26.7Very low32.1Very low124 Ų124146.6 Ų146.676%0.76181%0.811SS**PPolyproline II helixtrans-83.5140.9167.842.50000109.9S351T349-S351 PolarHBondContact O-N 3.13Å
350P28.7Very low32.1Very low126 Ų126140.9 Ų140.982%0.81880%0.796SS**PPolyproline II helixtrans-77.1124.2173.931.2-29000108.9
351S29.8Very low33.2Very low119 Ų119137.6 Ų137.683%0.83278%0.776SS**PPolyproline II helixtrans-100.2128.2168.564.70000110.2T349T349-S351 PolarHBondContact O-N 3.13Å
352D27.4Very low33.8Very low156 Ų156134.4 Ų134.483%0.83477%0.765SS**PPolyproline II helixtrans-54.5154.2-173.4-75.6-47.7000116.6
353S37.5Very low35.2Very low105 Ų105131.8 Ų131.873%0.73475%0.751SS**PPolyproline II helixtrans-50.8137.9175.452.90000116.2
354V28.1Very low36.5Very low135 Ų135128.1 Ų128.182%0.81873%0.732SS**  trans-129.6124.7149.2-1770000107.2S356V354-S356 PolarHBondContact O-N 3.44Å
355F32Very low38.6Very low205 Ų205120 Ų12090%0.89970%0.696SS**  trans-50.9107.6175-81.6-97.8000110.1
356S29.4Very low41.4Very low109 Ų109111.4 Ų111.476%0.76266%0.655SS**  trans-87.2120.1170.655.90000108.8V354 A358V354-S356 PolarHBondContact O-N 3.44Å; S356-A358 PolarHBondContact O-N 3.05Å
357D29.6Very low44.4Very low126 Ų126106.6 Ų106.667%0.67462%0.621SS**  trans-43.4117.6167.9-168.90.3000110.3S359 C360D357-S359 PolarHBondContact O-N 3.39Å; D357-C360 PolarHBondContact O-N 2.81Å; D357-C360 VanDerWaalsContact O-N 3.12Å
358A34.4Very low47.6Very low106 Ų10697.6 Ų97.688%0.87658%0.582SS**THydrogen-bonded Turntrans-64.2-5.2-173.400000113.5S356S356-A358 PolarHBondContact O-N 3.05Å
359S40.5Very low50.9Low102 Ų10289.8 Ų89.871%0.71355%0.546SS*.THydrogen-bonded Turntrans-84.2-12.2175.3-178.50000114.5D357D357-S359 PolarHBondContact O-N 3.39Å
360C35.5Very low54.1Low82 Ų8283.9 Ų83.955%0.55451%0.51SS*.SBendtrans-94.6123.2-178.8-162.70000110.7D357D357-C360 PolarHBondContact O-N 2.81Å; D357-C360 VanDerWaalsContact O-N 3.12Å
361P53Low57.1Low59 Ų5978.4 Ų78.438%0.38347%0.473SS..PPolyproline II helixtrans-54.9140.7175.3-24.233.1000111.6K363P361-K363 PolarHBondContact O-N 2.88Å
362S51.1Low59.9Low77 Ų7772.7 Ų72.754%0.53843%0.434SS..PPolyproline II helixtrans-56.8137.8176.11760000110.9D364 G365S362-D364 PolarHBondContact O-N 3.18Å; S362-D364 PolarHBondContact OG-N 2.97Å; S362-G365 PolarHBondContact O-N 3.11Å
363K62Low62.4Low121 Ų12165.3 Ų65.353%0.52639%0.394SS..THydrogen-bonded Turntrans-61-23.3174.7-62.8179.3-179.1178.60112.8F317 P361F317-K363 HydrophobicContact CE1-CG 4.44Å; F317-K363 HydrophobicContact CZ-CG 4.24Å; P361-K363 PolarHBondContact O-N 2.88Å
364D66.6Low64.1Low89 Ų8962.2 Ų62.248%0.47637%0.37SS..THydrogen-bonded Turntrans-94.31.1177.7-61.1-55.5000112.9K311 S362 T437K311-D364 WeakPolarHBondContact CD-OD1 3.24Å; K311-D364 IonicContact NZ-OD1 3.28Å; S362-D364 PolarHBondContact O-N 3.18Å; S362-D364 PolarHBondContact OG-N 2.97Å; D364-T437 WeakPolarHBondContact O-CB 3.47Å; D364-T437 PolarHBondContact O-OG1 3.3Å
365G78.1Confident66.1Low6 Ų657.9 Ų57.96%0.06235%0.345CS..  trans-85.5162.7-17700000114.5K321 S362 I367K321-G365 VanDerWaalsContact CE-O 3.27Å; K321-G365 WeakPolarHBondContact CE-O 3.46Å; K321-G365 PolarHBondContact NZ-O 3.5Å; S362-G365 PolarHBondContact O-N 3.11Å; G365-I367 VanDerWaalsContact C-N 3.33Å; G365-I367 PolarHBondContact O-N 3Å
366D91.9Very high67.8Low2 Ų255.1 Ų55.11%0.01133%0.33CS..SBendtrans6628.5172.3-39-57.3000114.7Y204 G318 K319 P320 K321 T437 T439Y204-D366 HydrophobicContact CE1-CB 4.45Å; Y204-D366 WeakPolarHBondContact OH-CB 3.32Å; Y204-D366 PolarHBondContact OH-OD1 2.95Å; G318-D366 WeakPolarHBondContact CA-OD2 3.1Å; G318-D366 PolarHBondContact N-OD2 3.42Å; G318-D366 VanDerWaalsContact N-OD2 3.16Å; K319-D366 VanDerWaalsContact O-CB 3.31Å; K319-D366 WeakPolarHBondContact O-CB 3.4Å; P320-D366 CarbonylContact C-O 3.58Å; P320-D366 WeakPolarHBondContact CA-O 3.49Å; K321-D366 PolarHBondContact N-O 3.3Å; D366-T437 PolarHBondContact N-O 3.44Å; D366-T439 PolarHBondContact OD1-OG1 3.02Å
367I94.3Very high69.9Low12 Ų1251.5 Ų51.56%0.06231%0.305CS..EExtended strand (participates in β ladder)trans-102.5138.8174.5-63.4175.1000109.8K311 K321 F323 G365 I369 Y436 T437K311-I367 HydrophobicContact CG-CD1 3.91Å; K321-I367 HydrophobicContact CB-CG1 4.2Å; K321-I367 HydrophobicContact CD-CG1 4.19Å; K321-I367 WeakPolarHBondContact O-CA 3.39Å; F323-I367 HydrophobicContact CD2-CG2 3.96Å; F323-I367 HydrophobicContact CE2-CG2 3.99Å; G365-I367 VanDerWaalsContact C-N 3.33Å; G365-I367 PolarHBondContact O-N 3Å; I367-I369 HydrophobicContact CG2-CD1 4.19Å; I367-I369 HydrophobicContact CG2-CG1 3.88Å; I367-Y436 CarbonylContact O-C 3.51Å; I367-Y436 VanDerWaalsContact O-CA 3.26Å; I367-Y436 WeakPolarHBondContact O-CA 3.32Å; I367-T437 PolarHBondContact N-OG1 3.45Å; I367-T437 VanDerWaalsContact N-OG1 3.15Å; I367-T437 PolarHBondContact O-N 3.03Å
368L96.5Very high71.9Confident0 Ų049.7 Ų49.70%029%0.291CS..EExtended strand (participates in β ladder)trans-127.9125168.217566000108.7K321 L322 F323 I409 L410 L413 L438K321-L368 PolarHBondContact O-N 3.19Å; L322-L368 CarbonylContact C-O 3.5Å; L322-L368 WeakPolarHBondContact CA-O 3.31Å; L322-L368 HydrophobicContact CD2-CB 3.72Å; L322-L368 HydrophobicContact CD2-CD2 3.82Å; L322-L368 HydrophobicContact CD2-CG 4.37Å; F323-L368 PolarHBondContact N-O 3.15Å; L368-I409 HydrophobicContact CD2-CB 4.37Å; L368-I409 HydrophobicContact CD2-CG1 3.46Å; L368-I409 VanDerWaalsContact CD2-CG1 3.46Å; L368-I409 HydrophobicContact CD2-CG2 3.93Å; L368-L410 HydrophobicContact CD1-CD2 4.05Å; L368-L413 HydrophobicContact CD1-CD1 3.78Å; L368-L413 HydrophobicContact CD2-CD1 3.74Å; L368-L413 HydrophobicContact CG-CD1 4.14Å; L368-L438 HydrophobicContact CB-CD1 4.07Å; L368-L438 HydrophobicContact CB-CD2 4.33Å; L368-L438 HydrophobicContact CB-CG 4.16Å; L368-L438 HydrophobicContact CD2-CD1 4.19Å
369I95.5Very high73.9Confident24 Ų2445.3 Ų45.312%0.12325%0.254CS..EExtended strand (participates in β ladder)trans-116.3111.1176.2-57.5162.1000107.6F307 F323 I367 M371 P434 K435F307-I369 HydrophobicContact CD1-CD1 4.13Å; F307-I369 HydrophobicContact CD1-CG1 4.26Å; F307-I369 HydrophobicContact CD2-CD1 3.78Å; F307-I369 HydrophobicContact CE1-CD1 3.99Å; F307-I369 HydrophobicContact CE1-CG1 3.9Å; F307-I369 HydrophobicContact CE1-CG2 4.22Å; F307-I369 HydrophobicContact CE2-CD1 3.61Å; F307-I369 HydrophobicContact CE2-CG1 4.35Å; F307-I369 HydrophobicContact CE2-CG2 4.45Å; F307-I369 HydrophobicContact CG-CD1 4.05Å; F307-I369 HydrophobicContact CZ-CD1 3.72Å; F307-I369 HydrophobicContact CZ-CG1 3.95Å; F307-I369 HydrophobicContact CZ-CG2 3.74Å; F323-I369 HydrophobicContact CB-CG1 4.29Å; F323-I369 HydrophobicContact CD2-CG1 4.32Å; F323-I369 CarbonylContact O-C 3.29Å; F323-I369 WeakPolarHBondContact O-CA 3.44Å; I367-I369 HydrophobicContact CG2-CD1 4.19Å; I367-I369 HydrophobicContact CG2-CG1 3.88Å; I369-M371 HydrophobicContact CG2-CG 3.97Å; I369-M371 HydrophobicContact CG2-SD 3.74Å; I369-P434 CarbonylContact O-C 3.44Å; I369-P434 VanDerWaalsContact O-CA 3.31Å; I369-P434 WeakPolarHBondContact O-CA 3.47Å; I369-K435 HydrophobicContact CB-CB 4.45Å; I369-K435 PolarHBondContact N-O 3.5Å; I369-K435 PolarHBondContact O-N 3.48Å
370G94.8Very high75.4Confident1 Ų141 Ų411%0.0122%0.223CC..EExtended strand (participates in β ladder)trans-94.599.9168.100000110.1F323 F324 I325 Y389F323-G370 PolarHBondContact O-N 3.47Å; F324-G370 WeakPolarHBondContact CA-O 3.35Å; I325-G370 PolarHBondContact N-O 2.94Å; G370-Y389 WeakPolarHBondContact CA-OH 3.27Å; G370-Y389 PolarHBondContact O-OH 2.92Å
371M92.1Very high77.3Confident10 Ų1039.4 Ų39.45%0.04921%0.205CC..EExtended strand (participates in β ladder)trans-82.3135.2171-61.2-61.6-65.900109.5L303 I325 Q329 I369 T373 P432 E433L303-M371 HydrophobicContact CD1-CE 3.69Å; L303-M371 HydrophobicContact CD1-SD 4.27Å; I325-M371 HydrophobicContact CB-CE 4.13Å; I325-M371 HydrophobicContact CB-SD 3.62Å; I325-M371 HydrophobicContact CG1-SD 3.83Å; I325-M371 HydrophobicContact CG2-CE 3.94Å; I325-M371 HydrophobicContact CG2-SD 4.05Å; Q329-M371 HydrophobicContact CG-CE 4.05Å; I369-M371 HydrophobicContact CG2-CG 3.97Å; I369-M371 HydrophobicContact CG2-SD 3.74Å; M371-T373 PolarHBondContact O-N 3.43Å; M371-P432 CarbonylContact O-C 3.24Å; M371-P432 VanDerWaalsContact O-CA 3.29Å; M371-P432 WeakPolarHBondContact O-CA 3.3Å; M371-P432 WeakPolarHBondContact O-CB 3.1Å; M371-E433 HydrophobicContact CB-CB 4.28Å; M371-E433 WeakPolarHBondContact CB-O 3.48Å; M371-E433 PolarHBondContact N-O 3Å; M371-E433 PolarHBondContact O-N 2.84Å
372A86.9Confident77.9Confident0 Ų037.8 Ų37.80%019%0.192CC..SBendtrans-61.8-27.5178.300000113.3I325 A379 Y389 Q430 P432I325-A372 WeakPolarHBondContact O-CB 3.44Å; I325-A372 PolarHBondContact O-N 2.73Å; A372-A379 HydrophobicContact CB-CB 4Å; A372-Y389 HydrophobicContact CB-CD1 3.49Å; A372-Y389 VanDerWaalsContact CB-CD1 3.49Å; A372-Y389 HydrophobicContact CB-CD2 4.29Å; A372-Y389 HydrophobicContact CB-CE1 4.14Å; A372-Y389 HydrophobicContact CB-CG 3.58Å; A372-Q430 PolarHBondContact O-NE2 3.06Å; A372-P432 WeakPolarHBondContact O-CA 3.43Å
373T79.7Confident78.7Confident1 Ų136.6 Ų36.61%0.00618%0.182CC..SBendtrans-148.7151-178.1-158.30000110.8Q329 M371 S377 K378 A379 M431Q329-T373 HydrophobicContact CB-CG2 4.07Å; Q329-T373 HydrophobicContact CG-CG2 4.02Å; M371-T373 PolarHBondContact O-N 3.43Å; T373-S377 VanDerWaalsContact CG2-O 3.26Å; T373-S377 WeakPolarHBondContact CG2-O 3.39Å; T373-S377 WeakPolarHBondContact OG1-CB 3.44Å; T373-K378 VanDerWaalsContact CB-O 3.32Å; T373-K378 WeakPolarHBondContact CB-O 3.4Å; T373-K378 PolarHBondContact OG1-O 2.86Å; T373-A379 HydrophobicContact CG2-CB 4.1Å; T373-M431 CarbonylContact C-O 3.52Å; T373-M431 VanDerWaalsContact CA-O 3.23Å; T373-M431 WeakPolarHBondContact CA-O 3.48Å
374V73.4Confident79Confident39 Ų3938 Ų3824%0.23619%0.191CC..  trans-65.5161.5173.2-73.30000111.4S377 M431 E433V374-S377 WeakPolarHBondContact CG2-OG 3.45Å; V374-S377 WeakPolarHBondContact O-CB 3.41Å; V374-S377 PolarHBondContact O-N 3.35Å; V374-M431 HydrophobicContact CG1-CB 4.17Å; V374-M431 HydrophobicContact CG1-CG 4.09Å; V374-M431 WeakPolarHBondContact CG1-O 3.37Å; V374-M431 HydrophobicContact CG2-CB 4.22Å; V374-M431 PolarHBondContact N-O 3.08Å; V374-E433 HydrophobicContact CG1-CB 3.85Å; V374-E433 HydrophobicContact CG1-CG 4.22Å
375P70.7Confident79.1Confident44 Ų4438.4 Ų38.429%0.28619%0.188SC..THydrogen-bonded Turntrans-50.7147.7172.7-28.436.1000112.8S377 E433P375-S377 PolarHBondContact O-N 3.03Å; P375-E433 WeakPolarHBondContact CD-OE2 3.44Å
376Y68.5Low79.1Confident147 Ų14738.1 Ų38.158%0.57619%0.185SC*.THydrogen-bonded Turntrans64.815.8-179-44.3-78.1000114.7R290 Q329 E331R290-Y376 VanDerWaalsContact NH1-CE1 3.29Å; R290-Y376 PolarHBondContact NH1-OH 3.27Å; Q329-Y376 VanDerWaalsContact O-CA 3.27Å; Q329-Y376 WeakPolarHBondContact O-CA 3.21Å; Q329-Y376 PolarHBondContact O-N 3.29Å; E331-Y376 HydrophobicContact CG-CD1 4.17Å; E331-Y376 HydrophobicContact CG-CE1 4.16Å
377S72.2Confident79Confident34 Ų3438 Ų3824%0.23818%0.184CC..  trans-123.5160.5-179.3-61.70000112.4Q329 D330 T373 V374 P375Q329-S377 CarbonylContact C-O 3.34Å; Q329-S377 PolarHBondContact N-O 3Å; D330-S377 PolarHBondContact N-O 3.04Å; T373-S377 VanDerWaalsContact CG2-O 3.26Å; T373-S377 WeakPolarHBondContact CG2-O 3.39Å; T373-S377 WeakPolarHBondContact OG1-CB 3.44Å; V374-S377 WeakPolarHBondContact CG2-OG 3.45Å; V374-S377 WeakPolarHBondContact O-CB 3.41Å; V374-S377 PolarHBondContact O-N 3.35Å; P375-S377 PolarHBondContact O-N 3.03Å
378K73.1Confident78.7Confident87 Ų8737.5 Ų37.538%0.37818%0.182SC..  trans-93.4157.4178-64.5-174.4178.4-172.80111.1D85 D330 T373 Y380D85-K378 IonicContact OD2-NZ 3.72Å; D85-K378 PolarHBondContact OD2-NZ 2.99Å; D330-K378 WeakPolarHBondContact OD2-CE 3.35Å; T373-K378 VanDerWaalsContact CB-O 3.32Å; T373-K378 WeakPolarHBondContact CB-O 3.4Å; T373-K378 PolarHBondContact OG1-O 2.86Å; K378-Y380 HydrophobicContact CB-CE1 4.42Å
379A75.1Confident78.5Confident14 Ų1437.6 Ų37.612%0.11618%0.182CC..  trans-114.2130.7173.200000109.9Q326 A372 T373Q326-A379 VanDerWaalsContact NE2-CB 3.28Å; A372-A379 HydrophobicContact CB-CB 4Å; T373-A379 HydrophobicContact CG2-CB 4.1Å
380Y71.6Confident78.5Confident12 Ų1236.5 Ų36.55%0.04718%0.176CC..  trans-102.2153.3-168.9-60.7-74.8000113.8D85 K378 I388 I426 N428 Q430D85-Y380 VanDerWaalsContact C-CD1 3.46Å; D85-Y380 HydrophobicContact CB-CD1 3.67Å; D85-Y380 HydrophobicContact CB-CE1 3.39Å; D85-Y380 WeakPolarHBondContact O-CD1 3.43Å; D85-Y380 WeakPolarHBondContact O-CE1 3.47Å; K378-Y380 HydrophobicContact CB-CE1 4.42Å; Y380-I388 PolarHBondContact O-N 2.61Å; Y380-I388 VanDerWaalsContact O-N 3.09Å; Y380-I426 HydrophobicContact CD2-CB 4.28Å; Y380-I426 HydrophobicContact CD2-CD1 4.02Å; Y380-I426 HydrophobicContact CD2-CG1 3.96Å; Y380-I426 HydrophobicContact CD2-CG2 3.54Å; Y380-I426 HydrophobicContact CE2-CG2 3.59Å; Y380-I426 HydrophobicContact CG-CG1 4.33Å; Y380-I426 HydrophobicContact CG-CG2 4.45Å; Y380-N428 VanDerWaalsContact CE2-O 3.28Å; Y380-N428 WeakPolarHBondContact CE2-O 3.37Å; Y380-N428 WeakPolarHBondContact OH-CB 3.29Å; Y380-Q430 HydrophobicContact CD2-CB 3.76Å; Y380-Q430 HydrophobicContact CD2-CG 4.26Å; Y380-Q430 HydrophobicContact CE2-CB 3.89Å
381R76.4Confident78.4Confident48 Ų4838.5 Ų38.518%0.18119%0.186CC..EExtended strand (participates in β ladder)trans-154.9143.7-172-174.517177.685.231.1112.1R230 L231 S233 S387R230-R381 VanDerWaalsContact C-CZ 3.44Å; R230-R381 VanDerWaalsContact C-NH2 3.26Å; R230-R381 VanDerWaalsContact CA-NH2 3.34Å; R230-R381 PolarHBondContact O-NH1 2.8Å; L231-R381 VanDerWaalsContact N-NH2 3.17Å; L231-R381 PolarHBondContact O-NH1 2.71Å; L231-R381 PolarHBondContact O-NH2 2.74Å; S233-R381 PolarHBondContact OG-NH1 3.23Å; R381-S387 VanDerWaalsContact CD-OG 3.24Å; R381-S387 WeakPolarHBondContact CD-OG 3.26Å; R381-S387 WeakPolarHBondContact CG-OG 3.38Å
382H65.8Low78.6Confident26 Ų2638.2 Ų38.212%0.1218%0.184CC..EExtended strand (participates in β ladder)trans-93.1137.9171.4-165.7-93.4000110.3E384 K385 G386 M425H382-E384 PolarHBondContact ND1-N 2.9Å; H382-E384 VanDerWaalsContact ND1-N 3.19Å; H382-E384 PolarHBondContact O-N 3.35Å; H382-K385 HydrophobicContact CB-CB 3.89Å; H382-K385 PolarHBondContact ND1-N 3.15Å; H382-K385 VanDerWaalsContact ND1-N 3.12Å; H382-G386 PolarHBondContact N-O 3.36Å; H382-G386 PolarHBondContact O-N 2.87Å; H382-M425 HydrophobicContact CB-CE 3.94Å; H382-M425 WeakPolarHBondContact CD2-CE 3.38Å
383T67.9Low79.1Confident51 Ų5138.2 Ų38.231%0.31318%0.184SC..THydrogen-bonded Turntrans-63.8-23.4-177480000113.9L231 G232L231-T383 CarbonylContact C-O 3.59Å; L231-T383 CarbonylContact O-C 3.59Å; L231-T383 VanDerWaalsContact O-CA 3.26Å; L231-T383 WeakPolarHBondContact O-CA 3.38Å; G232-T383 WeakPolarHBondContact CA-O 3.27Å; G232-T383 PolarHBondContact N-O 3.39Å; G232-T383 VanDerWaalsContact N-O 3.13Å
384E66.9Low79.9Confident152 Ų15238.7 Ų38.771%0.7119%0.187SC*.THydrogen-bonded Turntrans-115-28.8179.9-58.5-178.2163.500114H382H382-E384 PolarHBondContact ND1-N 2.9Å; H382-E384 VanDerWaalsContact ND1-N 3.19Å; H382-E384 PolarHBondContact O-N 3.35Å
385K69.4Low81Confident96 Ų9641.4 Ų41.442%0.41720%0.198SC..THydrogen-bonded Turntrans-100.4-7.7-170.9-64.5-177.5179.1-178.70112.8M235 H382 Q391M235-K385 VanDerWaalsContact CG-O 3.27Å; M235-K385 WeakPolarHBondContact CG-O 3.48Å; H382-K385 HydrophobicContact CB-CB 3.89Å; H382-K385 PolarHBondContact ND1-N 3.15Å; H382-K385 VanDerWaalsContact ND1-N 3.12Å; K385-Q391 PolarHBondContact O-NE2 2.83Å; K385-Q391 VanDerWaalsContact O-NE2 3.08Å
386G79.3Confident82.2Confident0 Ų039.7 Ų39.70%019%0.186CC..EExtended strand (participates in β ladder)trans87.8-166.9-176.900000113.3G232 D236 H382 Q391G232-G386 WeakPolarHBondContact O-CA 3.49Å; D236-G386 VanDerWaalsContact OD1-CA 3.28Å; D236-G386 WeakPolarHBondContact OD1-CA 3.22Å; H382-G386 PolarHBondContact N-O 3.36Å; H382-G386 PolarHBondContact O-N 2.87Å; G386-Q391 VanDerWaalsContact C-NE2 3.29Å; G386-Q391 PolarHBondContact O-NE2 2.84Å
387S88.3Confident83.6Confident0 Ų032.8 Ų32.80%016%0.159CC..EExtended strand (participates in β ladder)trans-79.2135.5-171.1-53.50000110.8D236 Q326 R381 Y389 I390 Q391D236-S387 PolarHBondContact OD1-N 3.19Å; D236-S387 VanDerWaalsContact OD2-CB 3.23Å; D236-S387 WeakPolarHBondContact OD2-CB 3.17Å; D236-S387 PolarHBondContact OD2-N 3.45Å; D236-S387 PolarHBondContact OD2-OG 3.43Å; Q326-S387 WeakPolarHBondContact CG-OG 3.5Å; R381-S387 VanDerWaalsContact CD-OG 3.24Å; R381-S387 WeakPolarHBondContact CD-OG 3.26Å; R381-S387 WeakPolarHBondContact CG-OG 3.38Å; S387-Y389 VanDerWaalsContact C-N 3.32Å; S387-Y389 PolarHBondContact O-N 2.97Å; S387-I390 PolarHBondContact O-N 3.43Å; S387-I390 VanDerWaalsContact O-N 3.17Å; S387-Q391 WeakPolarHBondContact O-CB 3.21Å; S387-Q391 WeakPolarHBondContact O-CG 3.41Å; S387-Q391 PolarHBondContact O-N 2.94Å
388I87.9Confident84.7Confident1 Ų134.2 Ų34.21%0.00516%0.162CC..Hα-helixtrans-64.3-42.8-174.7-66.6164.8000110.4Y380 I390 Q391 V392 H423 M425 I426Y380-I388 PolarHBondContact O-N 2.61Å; Y380-I388 VanDerWaalsContact O-N 3.09Å; I388-I390 VanDerWaalsContact C-N 3.34Å; I388-I390 PolarHBondContact O-N 3.41Å; I388-Q391 PolarHBondContact O-N 2.93Å; I388-V392 HydrophobicContact CG2-CG2 4.25Å; I388-V392 WeakPolarHBondContact O-CB 3.35Å; I388-V392 VanDerWaalsContact O-CG2 3.25Å; I388-V392 WeakPolarHBondContact O-CG2 3.44Å; I388-V392 PolarHBondContact O-N 3.36Å; I388-H423 HydrophobicContact CG2-CB 3.97Å; I388-M425 HydrophobicContact CD1-CB 3.56Å; I388-M425 HydrophobicContact CD1-CG 4.43Å; I388-M425 HydrophobicContact CD1-SD 4.31Å; I388-M425 HydrophobicContact CG1-CB 4.42Å; I388-M425 HydrophobicContact CG1-SD 4.19Å; I388-I426 HydrophobicContact CB-CD1 4.3Å; I388-I426 HydrophobicContact CD1-CD1 4.03Å; I388-I426 HydrophobicContact CD1-CG1 3.56Å; I388-I426 HydrophobicContact CG2-CD1 3.82Å; I388-I426 HydrophobicContact CG2-CG1 4.36Å
389Y94.1Very high85.8Confident2 Ų233.3 Ų33.31%0.00816%0.161CC..Hα-helixtrans-56.8-46.8174.4171.6-111.8000112.1G370 A372 S387 V392 L393 V416 V420 P432G370-Y389 WeakPolarHBondContact CA-OH 3.27Å; G370-Y389 PolarHBondContact O-OH 2.92Å; A372-Y389 HydrophobicContact CB-CD1 3.49Å; A372-Y389 VanDerWaalsContact CB-CD1 3.49Å; A372-Y389 HydrophobicContact CB-CD2 4.29Å; A372-Y389 HydrophobicContact CB-CE1 4.14Å; A372-Y389 HydrophobicContact CB-CG 3.58Å; S387-Y389 VanDerWaalsContact C-N 3.32Å; S387-Y389 PolarHBondContact O-N 2.97Å; Y389-V392 PolarHBondContact O-N 2.94Å; Y389-L393 HydrophobicContact CE1-CD2 4.19Å; Y389-L393 WeakPolarHBondContact O-CB 3.35Å; Y389-L393 PolarHBondContact O-N 3.26Å; Y389-V416 HydrophobicContact CD2-CG1 4.01Å; Y389-V416 HydrophobicContact CE2-CG1 3.85Å; Y389-V420 HydrophobicContact CD2-CG2 4.4Å; Y389-P432 HydrophobicContact CD2-CB 3.92Å; Y389-P432 HydrophobicContact CD2-CG 3.9Å; Y389-P432 HydrophobicContact CE2-CB 3.83Å; Y389-P432 HydrophobicContact CE2-CG 4.25Å
390I95.3Very high86.7Confident1 Ų133 Ų331%0.00516%0.158CC..Hα-helixtrans-68.7-43-178.1-62-61.7000111.5D236 L240 L285 Q326 S387 I388 V392 L393 C394D236-I390 HydrophobicContact CB-CG2 3.97Å; L240-I390 HydrophobicContact CD1-CD1 4.35Å; L240-I390 HydrophobicContact CD1-CG2 3.88Å; L240-I390 HydrophobicContact CD2-CG2 4Å; L240-I390 HydrophobicContact CG-CG2 3.73Å; L285-I390 HydrophobicContact CD2-CD1 4.37Å; L285-I390 HydrophobicContact CD2-CG1 3.86Å; Q326-I390 HydrophobicContact CB-CD1 4.22Å; Q326-I390 HydrophobicContact CB-CG1 4.13Å; Q326-I390 HydrophobicContact CG-CG1 4.4Å; S387-I390 PolarHBondContact O-N 3.43Å; S387-I390 VanDerWaalsContact O-N 3.17Å; I388-I390 VanDerWaalsContact C-N 3.34Å; I388-I390 PolarHBondContact O-N 3.41Å; I390-V392 PolarHBondContact O-N 3.44Å; I390-L393 HydrophobicContact CD1-CD2 4.45Å; I390-L393 PolarHBondContact O-N 3.24Å; I390-C394 WeakPolarHBondContact O-CB 3.22Å; I390-C394 PolarHBondContact O-N 3.49Å; I390-C394 PolarHBondContact O-SG 3.41Å
391Q92.6Very high87.7Confident44 Ų4432.9 Ų32.921%0.20616%0.16CC..Hα-helixtrans-57.8-50.1174.9-72.9175.764.600111.3K385 G386 S387 I388 C394 Q395K385-Q391 PolarHBondContact O-NE2 2.83Å; K385-Q391 VanDerWaalsContact O-NE2 3.08Å; G386-Q391 VanDerWaalsContact C-NE2 3.29Å; G386-Q391 PolarHBondContact O-NE2 2.84Å; S387-Q391 WeakPolarHBondContact O-CB 3.21Å; S387-Q391 WeakPolarHBondContact O-CG 3.41Å; S387-Q391 PolarHBondContact O-N 2.94Å; I388-Q391 PolarHBondContact O-N 2.93Å; Q391-C394 PolarHBondContact O-N 2.86Å; Q391-Q395 WeakPolarHBondContact O-CB 3.37Å; Q391-Q395 PolarHBondContact O-N 3.19Å
392V95.3Very high88.4Confident3 Ų335.3 Ų35.32%0.01818%0.176CC..Hα-helixtrans-66.2-41.3179.7175.30000111.2I388 Y389 I390 Q395 E396 V416 K419 V420I388-V392 HydrophobicContact CG2-CG2 4.25Å; I388-V392 WeakPolarHBondContact O-CB 3.35Å; I388-V392 VanDerWaalsContact O-CG2 3.25Å; I388-V392 WeakPolarHBondContact O-CG2 3.44Å; I388-V392 PolarHBondContact O-N 3.36Å; Y389-V392 PolarHBondContact O-N 2.94Å; I390-V392 PolarHBondContact O-N 3.44Å; V392-Q395 PolarHBondContact O-N 3.34Å; V392-E396 HydrophobicContact CG1-CG 4.28Å; V392-E396 WeakPolarHBondContact O-CB 3.26Å; V392-E396 WeakPolarHBondContact O-CG 3.2Å; V392-E396 PolarHBondContact O-N 3.32Å; V392-V416 HydrophobicContact CG1-CB 4.38Å; V392-V416 HydrophobicContact CG1-CG1 4.11Å; V392-V416 HydrophobicContact CG1-CG2 4.42Å; V392-K419 HydrophobicContact CG1-CB 3.47Å; V392-K419 VanDerWaalsContact CG1-CB 3.47Å; V392-K419 HydrophobicContact CG1-CD 4.11Å; V392-K419 HydrophobicContact CG1-CG 4.43Å; V392-V420 HydrophobicContact CB-CG2 3.89Å; V392-V420 HydrophobicContact CG1-CG2 3.91Å; V392-V420 HydrophobicContact CG2-CG2 4.09Å
393L97.3Very high89.4Confident0 Ų035.4 Ų35.40%018%0.18CC..Hα-helixtrans-57.8-51.4175.5175.565.1000110.8F324 Y389 I390 Q395 E396 L397 L413 V416F324-L393 HydrophobicContact CB-CD2 4.09Å; F324-L393 HydrophobicContact CD1-CD1 4.29Å; F324-L393 HydrophobicContact CD1-CD2 3.55Å; F324-L393 HydrophobicContact CD2-CD2 4.28Å; F324-L393 HydrophobicContact CE1-CD1 3.97Å; F324-L393 HydrophobicContact CE1-CD2 4Å; F324-L393 HydrophobicContact CG-CD2 3.7Å; F324-L393 HydrophobicContact CZ-CD1 4.49Å; Y389-L393 HydrophobicContact CE1-CD2 4.19Å; Y389-L393 WeakPolarHBondContact O-CB 3.35Å; Y389-L393 PolarHBondContact O-N 3.26Å; I390-L393 HydrophobicContact CD1-CD2 4.45Å; I390-L393 PolarHBondContact O-N 3.24Å; L393-Q395 VanDerWaalsContact C-N 3.34Å; L393-Q395 PolarHBondContact O-N 3.39Å; L393-E396 PolarHBondContact O-N 2.9Å; L393-L397 HydrophobicContact CD1-CD1 3.79Å; L393-L397 HydrophobicContact CD1-CG 4.16Å; L393-L397 HydrophobicContact CG-CD1 3.84Å; L393-L397 WeakPolarHBondContact O-CB 3.41Å; L393-L397 VanDerWaalsContact O-CG 3.25Å; L393-L397 WeakPolarHBondContact O-CG 3.37Å; L393-L397 PolarHBondContact O-N 3.34Å; L393-L413 HydrophobicContact CD1-CD2 3.78Å; L393-V416 HydrophobicContact CD1-CG2 4.19Å
394C97.2Very high90Very high11 Ų1139 Ų397%0.07421%0.205CC..Hα-helixtrans-60.8-44.6179.3-73.30000111.6L243 I390 Q391 E398L243-C394 VanDerWaalsContact CD2-CA 3.5Å; L243-C394 HydrophobicContact CD2-CB 3.8Å; I390-C394 WeakPolarHBondContact O-CB 3.22Å; I390-C394 PolarHBondContact O-N 3.49Å; I390-C394 PolarHBondContact O-SG 3.41Å; Q391-C394 PolarHBondContact O-N 2.86Å; C394-E398 WeakPolarHBondContact O-CB 3.3Å; C394-E398 PolarHBondContact O-N 3.34Å
395Q95.9Very high90.8Very high97 Ų9738.4 Ų38.445%0.45320%0.2SC..Hα-helixtrans-62.1-45.7178.5-171.4-174.427.900112.1Q391 V392 L393 E398 N399Q391-Q395 WeakPolarHBondContact O-CB 3.37Å; Q391-Q395 PolarHBondContact O-N 3.19Å; V392-Q395 PolarHBondContact O-N 3.34Å; L393-Q395 VanDerWaalsContact C-N 3.34Å; L393-Q395 PolarHBondContact O-N 3.39Å; Q395-E398 PolarHBondContact O-N 2.94Å; Q395-N399 WeakPolarHBondContact O-CB 3.28Å; Q395-N399 PolarHBondContact O-N 3.31Å; Q395-N399 PolarHBondContact O-ND2 3.15Å
396E97.1Very high91.5Very high7 Ų738.4 Ų38.43%0.03320%0.197CC..Hα-helixtrans-72.1-35.1-177.9-71.5-54.895.300112.9V392 L393 N399 A400 V412 R415 V416 K419V392-E396 HydrophobicContact CG1-CG 4.28Å; V392-E396 WeakPolarHBondContact O-CB 3.26Å; V392-E396 WeakPolarHBondContact O-CG 3.2Å; V392-E396 PolarHBondContact O-N 3.32Å; L393-E396 PolarHBondContact O-N 2.9Å; E396-N399 PolarHBondContact O-N 3.01Å; E396-N399 PolarHBondContact OE1-ND2 2.85Å; E396-A400 VanDerWaalsContact O-CB 3.32Å; E396-A400 WeakPolarHBondContact O-CB 3.47Å; E396-A400 PolarHBondContact O-N 3.42Å; E396-V412 HydrophobicContact CB-CG1 3.82Å; E396-R415 HydrophobicContact CG-CB 4.22Å; E396-R415 WeakPolarHBondContact OE2-CB 3.44Å; E396-R415 WeakPolarHBondContact OE2-CD 3.49Å; E396-V416 HydrophobicContact CB-CG2 3.75Å; E396-V416 HydrophobicContact CG-CG2 3.96Å; E396-K419 VanDerWaalsContact CD-CE 3.49Å; E396-K419 HydrophobicContact CG-CD 3.9Å; E396-K419 WeakPolarHBondContact OE1-CE 3.47Å; E396-K419 IonicContact OE1-NZ 3.49Å; E396-K419 PolarHBondContact OE1-NZ 3.17Å; E396-K419 IonicContact OE2-NZ 3.73Å
397L97Very high92Very high3 Ų339.5 Ų39.52%0.01620%0.203CC..Hα-helixtrans-62.5-44.2170.8-75.3169.7000111.2L243 F244 F247 L393 A400 A401 I409 V412 L444L243-L397 HydrophobicContact CD2-CB 3.93Å; L243-L397 HydrophobicContact CD2-CD1 3.96Å; F244-L397 HydrophobicContact CZ-CD1 4.38Å; F247-L397 HydrophobicContact CE2-CB 4.02Å; F247-L397 HydrophobicContact CZ-CB 4.08Å; L393-L397 HydrophobicContact CD1-CD1 3.79Å; L393-L397 HydrophobicContact CD1-CG 4.16Å; L393-L397 HydrophobicContact CG-CD1 3.84Å; L393-L397 WeakPolarHBondContact O-CB 3.41Å; L393-L397 VanDerWaalsContact O-CG 3.25Å; L393-L397 WeakPolarHBondContact O-CG 3.37Å; L393-L397 PolarHBondContact O-N 3.34Å; L397-A400 PolarHBondContact O-N 3.36Å; L397-A401 WeakPolarHBondContact O-CB 3.27Å; L397-A401 PolarHBondContact O-N 2.89Å; L397-I409 HydrophobicContact CD2-CD1 3.58Å; L397-V412 HydrophobicContact CD2-CG1 4.01Å; L397-V412 HydrophobicContact CG-CG1 4.19Å; L397-L444 HydrophobicContact CD2-CD1 3.88Å
398E96.2Very high92.4Very high64 Ų6440.3 Ų40.330%0.29921%0.207SC..Hα-helixtrans-64.7-43.4176174158.1-148.200112.4L243 R246 C394 Q395 A400 A401 N402 F446L243-E398 HydrophobicContact CD1-CB 4.08Å; R246-E398 IonicContact CZ-OE1 3.79Å; R246-E398 IonicContact NH1-OE1 3.77Å; R246-E398 PolarHBondContact NH1-OE1 3.4Å; R246-E398 IonicContact NH1-OE2 3.75Å; R246-E398 IonicContact NH2-OE1 3.62Å; R246-E398 PolarHBondContact NH2-OE1 3.15Å; C394-E398 WeakPolarHBondContact O-CB 3.3Å; C394-E398 PolarHBondContact O-N 3.34Å; Q395-E398 PolarHBondContact O-N 2.94Å; E398-A400 VanDerWaalsContact C-N 3.32Å; E398-A400 PolarHBondContact O-N 3.05Å; E398-A401 WeakPolarHBondContact O-CB 3.27Å; E398-A401 PolarHBondContact O-N 3.1Å; E398-N402 WeakPolarHBondContact CG-ND2 3.44Å; E398-N402 WeakPolarHBondContact O-CB 3.18Å; E398-N402 PolarHBondContact O-N 3.44Å; E398-N402 PolarHBondContact O-ND2 3.28Å; E398-N402 VanDerWaalsContact O-ND2 3.14Å; E398-F446 HydrophobicContact CB-CZ 4.23Å; E398-F446 HydrophobicContact CG-CE2 4.34Å; E398-F446 HydrophobicContact CG-CZ 3.94Å
399N94.3Very high92.8Very high68 Ų6840.4 Ų40.436%0.36421%0.208SC..Hα-helixtrans-60.2-43.1175.9-73.1-24.1000111.5Q395 E396 N402 S403Q395-N399 WeakPolarHBondContact O-CB 3.28Å; Q395-N399 PolarHBondContact O-N 3.31Å; Q395-N399 PolarHBondContact O-ND2 3.15Å; E396-N399 PolarHBondContact O-N 3.01Å; E396-N399 PolarHBondContact OE1-ND2 2.85Å; N399-N402 PolarHBondContact O-N 3.47Å; N399-S403 WeakPolarHBondContact O-CB 3.48Å; N399-S403 PolarHBondContact O-N 3.25Å
400A94.8Very high92.9Very high6 Ų642.5 Ų42.55%0.0522%0.218CC..Hα-helixtrans-65.2-40.2176.500000112E396 L397 E398 N402 S403 D407 V412 R445E396-A400 VanDerWaalsContact O-CB 3.32Å; E396-A400 WeakPolarHBondContact O-CB 3.47Å; E396-A400 PolarHBondContact O-N 3.42Å; L397-A400 PolarHBondContact O-N 3.36Å; E398-A400 VanDerWaalsContact C-N 3.32Å; E398-A400 PolarHBondContact O-N 3.05Å; A400-N402 PolarHBondContact O-N 3.43Å; A400-S403 PolarHBondContact O-N 3.02Å; A400-D407 HydrophobicContact CB-CB 4.18Å; A400-V412 HydrophobicContact CB-CG2 3.44Å; A400-V412 VanDerWaalsContact CB-CG2 3.44Å; A400-R445 PolarHBondContact O-NH1 3.39Å
401A93.1Very high92.9Very high10 Ų1044.8 Ų44.88%0.08323%0.233CC..Hα-helixtrans-62.5-42.6177.600000112.4F247 L397 E398 R445 F446F247-A401 HydrophobicContact CE1-CB 3.56Å; F247-A401 HydrophobicContact CZ-CB 3.94Å; L397-A401 WeakPolarHBondContact O-CB 3.27Å; L397-A401 PolarHBondContact O-N 2.89Å; E398-A401 WeakPolarHBondContact O-CB 3.27Å; E398-A401 PolarHBondContact O-N 3.1Å; A401-R445 PolarHBondContact O-NH1 3.22Å; A401-F446 HydrophobicContact CB-CD1 4.11Å; A401-F446 HydrophobicContact CB-CD2 3.79Å; A401-F446 HydrophobicContact CB-CE1 3.85Å; A401-F446 HydrophobicContact CB-CE2 3.49Å; A401-F446 VanDerWaalsContact CB-CE2 3.49Å; A401-F446 HydrophobicContact CB-CG 4.09Å; A401-F446 HydrophobicContact CB-CZ 3.55Å
402N90.6Very high93.2Very high99 Ų9942.9 Ų42.953%0.52922%0.224SC..Hα-helixtrans-79-22.3179.5-71.5-40.4000113.7E398 N399 A400 F446E398-N402 WeakPolarHBondContact CG-ND2 3.44Å; E398-N402 WeakPolarHBondContact O-CB 3.18Å; E398-N402 PolarHBondContact O-N 3.44Å; E398-N402 PolarHBondContact O-ND2 3.28Å; E398-N402 VanDerWaalsContact O-ND2 3.14Å; N399-N402 PolarHBondContact O-N 3.47Å; A400-N402 PolarHBondContact O-N 3.43Å; N402-F446 VanDerWaalsContact OD1-CE2 3.31Å; N402-F446 WeakPolarHBondContact OD1-CE2 3.41Å
403S86.5Confident93.3Very high28 Ų2842.9 Ų42.920%0.19622%0.224CC..SBendtrans-69.7138.9-179.6175.10000110.8N399 A400 K405 R445N399-S403 WeakPolarHBondContact O-CB 3.48Å; N399-S403 PolarHBondContact O-N 3.25Å; A400-S403 PolarHBondContact O-N 3.02Å; S403-K405 PolarHBondContact O-N 3.02Å; S403-K405 WeakPolarHBondContact OG-CB 3.42Å; S403-K405 PolarHBondContact OG-N 3.27Å; S403-K405 VanDerWaalsContact OG-N 3.16Å; S403-R445 PolarHBondContact O-NH1 3.44Å
404P81.7Confident93.2Very high128 Ų12847.2 Ų47.283%0.83125%0.25SS*.SBendtrans-64.3-19.917227.5-34.1000112.1
405K82.2Confident93.2Very high139 Ų13949.4 Ų49.460%0.60426%0.257SS*.SBendtrans-69.6134.3176.2-57.8-177.3177.9-179.20110.1S403 D407 R445S403-K405 PolarHBondContact O-N 3.02Å; S403-K405 WeakPolarHBondContact OG-CB 3.42Å; S403-K405 PolarHBondContact OG-N 3.27Å; S403-K405 VanDerWaalsContact OG-N 3.16Å; K405-D407 PolarHBondContact O-N 2.77Å; K405-R445 PolarHBondContact O-NH2 2.84Å
406R84.4Confident93.2Very high96 Ų9644.8 Ų44.836%0.36224%0.236SC..  trans-80.165.3173-69.3-175.683.1-174.66.1110.3E198 D408E198-R406 IonicContact OE1-CZ 2.8Å; E198-R406 IonicContact OE1-NH1 3.64Å; E198-R406 PolarHBondContact OE1-NH1 3.46Å; E198-R406 IonicContact OE2-CZ 3.14Å; E198-R406 IonicContact OE2-NH1 2.66Å; E198-R406 PolarHBondContact OE2-NH1 3.37Å; R406-D408 PolarHBondContact O-N 3.39Å
407D91.3Very high93Very high22 Ų2246 Ų4612%0.11824%0.242CC..  trans-68.3120.2177.6-66.7-39.9000109.7A400 K405 T411 V412 R415A400-D407 HydrophobicContact CB-CB 4.18Å; K405-D407 PolarHBondContact O-N 2.77Å; D407-T411 HydrophobicContact CB-CG2 4.33Å; D407-V412 HydrophobicContact CB-CG2 4.39Å; D407-R415 IonicContact OD1-CZ 3.81Å; D407-R415 IonicContact OD1-NH2 2.79Å; D407-R415 PolarHBondContact OD1-NH2 3.03Å; D407-R415 IonicContact OD2-CZ 3.5Å; D407-R415 IonicContact OD2-NH1 2.62Å; D407-R415 PolarHBondContact OD2-NH1 3.19Å; D407-R415 IonicContact OD2-NH2 3.69Å; D407-R415 PolarHBondContact OD2-NH2 3.33Å
408D95Very high92.8Very high17 Ų1753.1 Ų53.19%0.09127%0.269CS..  trans-76.7163.3174.264.482.3000111.9R406 L410 T411 V412 R441 L442 V443R406-D408 PolarHBondContact O-N 3.39Å; D408-L410 PolarHBondContact O-N 2.81Å; D408-L410 VanDerWaalsContact O-N 3.17Å; D408-L410 WeakPolarHBondContact OD1-CB 3.41Å; D408-L410 PolarHBondContact OD1-N 3.08Å; D408-T411 WeakPolarHBondContact O-CA 3.49Å; D408-T411 VanDerWaalsContact O-CB 3.31Å; D408-T411 WeakPolarHBondContact O-CB 3.49Å; D408-T411 PolarHBondContact O-N 2.85Å; D408-T411 PolarHBondContact OD1-N 2.99Å; D408-T411 PolarHBondContact OD1-OG1 3.34Å; D408-T411 PolarHBondContact OD2-OG1 3.21Å; D408-T411 VanDerWaalsContact OD2-OG1 3.07Å; D408-V412 WeakPolarHBondContact O-CG2 3.29Å; D408-V412 PolarHBondContact O-N 2.91Å; D408-R441 HydrophobicContact CB-CB 4.21Å; D408-R441 IonicContact OD2-CZ 2.67Å; D408-R441 IonicContact OD2-NE 3.99Å; D408-R441 PolarHBondContact OD2-NE 3Å; D408-R441 IonicContact OD2-NH2 3.71Å; D408-R441 PolarHBondContact OD2-NH2 2.66Å; D408-R441 VanDerWaalsContact OD2-NH2 3.07Å; D408-L442 CarbonylContact C-O 3.1Å; D408-L442 VanDerWaalsContact CA-O 3.25Å; D408-L442 WeakPolarHBondContact CA-O 3.45Å; D408-V443 HydrophobicContact CB-CG2 4.32Å
409I96.9Very high92.6Very high4 Ų453.2 Ų53.22%0.02127%0.268CS..Hα-helixtrans-58.1-32.5-174.2-166.558.9000113.3L368 L397 V412 L413 L438 L442 L444L368-I409 HydrophobicContact CD2-CB 4.37Å; L368-I409 HydrophobicContact CD2-CG1 3.46Å; L368-I409 VanDerWaalsContact CD2-CG1 3.46Å; L368-I409 HydrophobicContact CD2-CG2 3.93Å; L397-I409 HydrophobicContact CD2-CD1 3.58Å; I409-V412 PolarHBondContact O-N 3.16Å; I409-L413 HydrophobicContact CG1-CD1 4.22Å; I409-L413 HydrophobicContact CG1-CG 4.44Å; I409-L413 WeakPolarHBondContact O-CB 3.43Å; I409-L413 VanDerWaalsContact O-CG 3.26Å; I409-L413 WeakPolarHBondContact O-CG 3.47Å; I409-L413 PolarHBondContact O-N 3.36Å; I409-L438 HydrophobicContact CG2-CD1 3.66Å; I409-L442 HydrophobicContact CB-CB 4.23Å; I409-L442 HydrophobicContact CB-CD2 4.35Å; I409-L442 HydrophobicContact CB-CG 4.44Å; I409-L442 HydrophobicContact CG2-CB 3.78Å; I409-L442 HydrophobicContact CG2-CD2 4.22Å; I409-L442 HydrophobicContact CG2-CG 4.39Å; I409-L442 PolarHBondContact N-O 3.15Å; I409-L444 HydrophobicContact CD1-CD1 4.27Å
410L96.6Very high92.2Very high45 Ų4550 Ų5024%0.23625%0.251CS..Hα-helixtrans-73.9-38.2179.5-57.6-179.6000110.6L368 D408 V412 L413 T414 Y436L368-L410 HydrophobicContact CD1-CD2 4.05Å; D408-L410 PolarHBondContact O-N 2.81Å; D408-L410 VanDerWaalsContact O-N 3.17Å; D408-L410 WeakPolarHBondContact OD1-CB 3.41Å; D408-L410 PolarHBondContact OD1-N 3.08Å; L410-V412 VanDerWaalsContact C-N 3.31Å; L410-V412 PolarHBondContact O-N 2.56Å; L410-L413 PolarHBondContact O-N 3.31Å; L410-T414 WeakPolarHBondContact O-CB 3.32Å; L410-T414 PolarHBondContact O-N 3.39Å; L410-T414 PolarHBondContact O-OG1 2.91Å; L410-Y436 HydrophobicContact CD1-CD1 4.33Å; L410-Y436 HydrophobicContact CD1-CD2 4.04Å; L410-Y436 HydrophobicContact CD1-CE1 3.96Å; L410-Y436 HydrophobicContact CD1-CE2 3.63Å; L410-Y436 HydrophobicContact CD1-CG 4.38Å; L410-Y436 HydrophobicContact CD2-CD1 3.6Å; L410-Y436 HydrophobicContact CD2-CD2 4.29Å; L410-Y436 HydrophobicContact CD2-CE1 3.89Å; L410-Y436 HydrophobicContact CD2-CG 3.83Å
411T96Very high91.8Very high50 Ų5051.5 Ų51.531%0.30726%0.259SS..Hα-helixtrans-59.1-44.6169.5-62.70000110.8D407 D408 T414 R415D407-T411 HydrophobicContact CB-CG2 4.33Å; D408-T411 WeakPolarHBondContact O-CA 3.49Å; D408-T411 VanDerWaalsContact O-CB 3.31Å; D408-T411 WeakPolarHBondContact O-CB 3.49Å; D408-T411 PolarHBondContact O-N 2.85Å; D408-T411 PolarHBondContact OD1-N 2.99Å; D408-T411 PolarHBondContact OD1-OG1 3.34Å; D408-T411 PolarHBondContact OD2-OG1 3.21Å; D408-T411 VanDerWaalsContact OD2-OG1 3.07Å; T411-T414 WeakPolarHBondContact O-CB 3.47Å; T411-T414 PolarHBondContact O-N 3.19Å; T411-R415 WeakPolarHBondContact O-CG 3.48Å; T411-R415 PolarHBondContact O-N 3.18Å
412V97.3Very high91.1Very high4 Ų455.2 Ų55.22%0.02428%0.277CS..Hα-helixtrans-60.8-50.4175.7179.10000111E396 L397 A400 D407 D408 I409 L410 T414 R415 V416E396-V412 HydrophobicContact CB-CG1 3.82Å; L397-V412 HydrophobicContact CD2-CG1 4.01Å; L397-V412 HydrophobicContact CG-CG1 4.19Å; A400-V412 HydrophobicContact CB-CG2 3.44Å; A400-V412 VanDerWaalsContact CB-CG2 3.44Å; D407-V412 HydrophobicContact CB-CG2 4.39Å; D408-V412 WeakPolarHBondContact O-CG2 3.29Å; D408-V412 PolarHBondContact O-N 2.91Å; I409-V412 PolarHBondContact O-N 3.16Å; L410-V412 VanDerWaalsContact C-N 3.31Å; L410-V412 PolarHBondContact O-N 2.56Å; V412-T414 VanDerWaalsContact C-N 3.26Å; V412-T414 PolarHBondContact O-N 3.2Å; V412-R415 WeakPolarHBondContact O-CA 3.44Å; V412-R415 WeakPolarHBondContact O-CB 3.35Å; V412-R415 PolarHBondContact O-N 3.32Å; V412-V416 HydrophobicContact CG1-CG2 4.46Å; V412-V416 WeakPolarHBondContact O-CG2 3.45Å; V412-V416 PolarHBondContact O-N 2.9Å
413L97.1Very high90.3Very high2 Ų251.9 Ų51.91%0.0126%0.258CS..Hα-helixtrans-64.6-29.9-179.4-70.1175.2000112.8F324 L368 L393 I409 L410 R415 V416 N417 P434F324-L413 HydrophobicContact CE1-CD2 4.24Å; L368-L413 HydrophobicContact CD1-CD1 3.78Å; L368-L413 HydrophobicContact CD2-CD1 3.74Å; L368-L413 HydrophobicContact CG-CD1 4.14Å; L393-L413 HydrophobicContact CD1-CD2 3.78Å; I409-L413 HydrophobicContact CG1-CD1 4.22Å; I409-L413 HydrophobicContact CG1-CG 4.44Å; I409-L413 WeakPolarHBondContact O-CB 3.43Å; I409-L413 VanDerWaalsContact O-CG 3.26Å; I409-L413 WeakPolarHBondContact O-CG 3.47Å; I409-L413 PolarHBondContact O-N 3.36Å; L410-L413 PolarHBondContact O-N 3.31Å; L413-R415 VanDerWaalsContact C-N 3.33Å; L413-R415 PolarHBondContact O-N 2.95Å; L413-V416 HydrophobicContact CD2-CG2 4.44Å; L413-V416 WeakPolarHBondContact O-CB 3.32Å; L413-V416 PolarHBondContact O-N 3.36Å; L413-N417 PolarHBondContact O-N 3.24Å; L413-N417 PolarHBondContact O-OD1 2.91Å; L413-P434 HydrophobicContact CB-CB 4.31Å; L413-P434 HydrophobicContact CB-CG 4.48Å; L413-P434 HydrophobicContact CD1-CB 3.95Å
414T96.1Very high88.9Confident91 Ų9155.7 Ų55.756%0.55827%0.271SS*.Hα-helixtrans-63.3-40.1170.3-58.10000111.5L410 T411 V412 N417 R418L410-T414 WeakPolarHBondContact O-CB 3.32Å; L410-T414 PolarHBondContact O-N 3.39Å; L410-T414 PolarHBondContact O-OG1 2.91Å; T411-T414 WeakPolarHBondContact O-CB 3.47Å; T411-T414 PolarHBondContact O-N 3.19Å; V412-T414 VanDerWaalsContact C-N 3.26Å; V412-T414 PolarHBondContact O-N 3.2Å; T414-N417 PolarHBondContact O-N 3.48Å; T414-R418 PolarHBondContact O-N 3.23Å; T414-R418 VanDerWaalsContact O-N 3.07Å
415R96.4Very high87.4Confident58 Ų5849.9 Ų49.922%0.21923%0.233CC..Hα-helixtrans-68.5-38.1173.9-60.9174.6-172.7162.25.9111.6E396 D407 T411 V412 L413 R418 K419E396-R415 HydrophobicContact CG-CB 4.22Å; E396-R415 WeakPolarHBondContact OE2-CB 3.44Å; E396-R415 WeakPolarHBondContact OE2-CD 3.49Å; D407-R415 IonicContact OD1-CZ 3.81Å; D407-R415 IonicContact OD1-NH2 2.79Å; D407-R415 PolarHBondContact OD1-NH2 3.03Å; D407-R415 IonicContact OD2-CZ 3.5Å; D407-R415 IonicContact OD2-NH1 2.62Å; D407-R415 PolarHBondContact OD2-NH1 3.19Å; D407-R415 IonicContact OD2-NH2 3.69Å; D407-R415 PolarHBondContact OD2-NH2 3.33Å; T411-R415 WeakPolarHBondContact O-CG 3.48Å; T411-R415 PolarHBondContact O-N 3.18Å; V412-R415 WeakPolarHBondContact O-CA 3.44Å; V412-R415 WeakPolarHBondContact O-CB 3.35Å; V412-R415 PolarHBondContact O-N 3.32Å; L413-R415 VanDerWaalsContact C-N 3.33Å; L413-R415 PolarHBondContact O-N 2.95Å; R415-R418 PolarHBondContact O-N 3.28Å; R415-K419 WeakPolarHBondContact O-CB 3.34Å; R415-K419 WeakPolarHBondContact O-CG 3.39Å; R415-K419 PolarHBondContact O-N 2.9Å
416V96.3Very high86.1Confident0 Ų044 Ų440%021%0.208CC..Hα-helixtrans-58-49.9172.51750000110Y389 V392 L393 E396 V412 L413 R418 K419 V420Y389-V416 HydrophobicContact CD2-CG1 4.01Å; Y389-V416 HydrophobicContact CE2-CG1 3.85Å; V392-V416 HydrophobicContact CG1-CB 4.38Å; V392-V416 HydrophobicContact CG1-CG1 4.11Å; V392-V416 HydrophobicContact CG1-CG2 4.42Å; L393-V416 HydrophobicContact CD1-CG2 4.19Å; E396-V416 HydrophobicContact CB-CG2 3.75Å; E396-V416 HydrophobicContact CG-CG2 3.96Å; V412-V416 HydrophobicContact CG1-CG2 4.46Å; V412-V416 WeakPolarHBondContact O-CG2 3.45Å; V412-V416 PolarHBondContact O-N 2.9Å; L413-V416 HydrophobicContact CD2-CG2 4.44Å; L413-V416 WeakPolarHBondContact O-CB 3.32Å; L413-V416 PolarHBondContact O-N 3.36Å; V416-R418 VanDerWaalsContact C-N 3.33Å; V416-R418 PolarHBondContact O-N 3.05Å; V416-K419 PolarHBondContact O-N 3.2Å; V416-K419 VanDerWaalsContact O-N 3.16Å; V416-V420 HydrophobicContact CG1-CG2 4Å; V416-V420 WeakPolarHBondContact O-CB 3.22Å; V416-V420 WeakPolarHBondContact O-CG2 3.4Å; V416-V420 PolarHBondContact O-N 3.44Å
417N94Very high84.4Confident32 Ų3247.2 Ų47.217%0.17122%0.22CC..Hα-helixtrans-55-49.2176.9-74.39.1000111.6L413 T414 K419 N421 M431 P432 P434L413-N417 PolarHBondContact O-N 3.24Å; L413-N417 PolarHBondContact O-OD1 2.91Å; T414-N417 PolarHBondContact O-N 3.48Å; N417-K419 PolarHBondContact O-N 3.26Å; N417-N421 WeakPolarHBondContact O-CB 3.49Å; N417-N421 PolarHBondContact O-N 3.21Å; N417-M431 HydrophobicContact CB-SD 4.14Å; N417-P432 PolarHBondContact ND2-O 3.49Å; N417-P432 WeakPolarHBondContact OD1-CB 3.47Å; N417-P432 PolarHBondContact OD1-O 2.67Å; N417-P434 WeakPolarHBondContact ND2-CD 3.47Å
418R91.3Very high83Confident152 Ų15251.5 Ų51.557%0.57424%0.243SC*.Hα-helixtrans-60-45.8177.9-178.7175.861.5179-0.7111.9T414 R415 V416 N422T414-R418 PolarHBondContact O-N 3.23Å; T414-R418 VanDerWaalsContact O-N 3.07Å; R415-R418 PolarHBondContact O-N 3.28Å; V416-R418 VanDerWaalsContact C-N 3.33Å; V416-R418 PolarHBondContact O-N 3.05Å; R418-N422 WeakPolarHBondContact O-CB 3.48Å; R418-N422 VanDerWaalsContact O-CG 3.29Å; R418-N422 PolarHBondContact O-N 2.91Å; R418-N422 PolarHBondContact O-ND2 2.79Å
419K92.3Very high81.9Confident66 Ų6658.6 Ų58.629%0.28727%0.273SS..Hα-helixtrans-71.9-37.2-177.3-79.3-168.3173.8-165.60112.8V392 E396 R415 V416 N417 N422 H423V392-K419 HydrophobicContact CG1-CB 3.47Å; V392-K419 VanDerWaalsContact CG1-CB 3.47Å; V392-K419 HydrophobicContact CG1-CD 4.11Å; V392-K419 HydrophobicContact CG1-CG 4.43Å; E396-K419 VanDerWaalsContact CD-CE 3.49Å; E396-K419 HydrophobicContact CG-CD 3.9Å; E396-K419 WeakPolarHBondContact OE1-CE 3.47Å; E396-K419 IonicContact OE1-NZ 3.49Å; E396-K419 PolarHBondContact OE1-NZ 3.17Å; E396-K419 IonicContact OE2-NZ 3.73Å; R415-K419 WeakPolarHBondContact O-CB 3.34Å; R415-K419 WeakPolarHBondContact O-CG 3.39Å; R415-K419 PolarHBondContact O-N 2.9Å; V416-K419 PolarHBondContact O-N 3.2Å; V416-K419 VanDerWaalsContact O-N 3.16Å; N417-K419 PolarHBondContact O-N 3.26Å; K419-N422 CarbonylContact O-C 3.39Å; K419-H423 VanDerWaalsContact O-CA 3.27Å; K419-H423 WeakPolarHBondContact O-CA 3.2Å; K419-H423 VanDerWaalsContact O-CB 3.26Å; K419-H423 WeakPolarHBondContact O-CB 3.13Å; K419-H423 PolarHBondContact O-N 3.26Å
420V87.1Confident81.1Confident0 Ų058.4 Ų58.40%027%0.272CS..Hα-helixtrans-70.7-45.3175177.50000110.5Y389 V392 V416 N422 H423 I426 Q430 P432Y389-V420 HydrophobicContact CD2-CG2 4.4Å; V392-V420 HydrophobicContact CB-CG2 3.89Å; V392-V420 HydrophobicContact CG1-CG2 3.91Å; V392-V420 HydrophobicContact CG2-CG2 4.09Å; V416-V420 HydrophobicContact CG1-CG2 4Å; V416-V420 WeakPolarHBondContact O-CB 3.22Å; V416-V420 WeakPolarHBondContact O-CG2 3.4Å; V416-V420 PolarHBondContact O-N 3.44Å; V420-N422 VanDerWaalsContact C-N 3.26Å; V420-N422 PolarHBondContact O-N 3.25Å; V420-H423 WeakPolarHBondContact O-CB 3.48Å; V420-H423 PolarHBondContact O-N 2.96Å; V420-I426 HydrophobicContact CG1-CD1 3.85Å; V420-Q430 HydrophobicContact CG1-CB 3.96Å; V420-Q430 HydrophobicContact CG1-CG 3.79Å; V420-P432 HydrophobicContact CB-CG 3.53Å; V420-P432 HydrophobicContact CG1-CG 3.62Å; V420-P432 HydrophobicContact CG2-CG 3.76Å
421N85.2Confident80.9Confident39 Ų3959.4 Ų59.421%0.20928%0.276CS..Hα-helixtrans-61.9-34.5178.2175.876.8000113.2N417 H423 Q430 M431N417-N421 WeakPolarHBondContact O-CB 3.49Å; N417-N421 PolarHBondContact O-N 3.21Å; N421-H423 VanDerWaalsContact C-N 3.35Å; N421-Q430 VanDerWaalsContact CA-O 3.24Å; N421-Q430 WeakPolarHBondContact CA-O 3.32Å; N421-Q430 PolarHBondContact N-O 3.26Å; N421-M431 HydrophobicContact CB-CE 3.53Å; N421-M431 HydrophobicContact CB-SD 4.23Å; N421-M431 VanDerWaalsContact CG-CE 3.42Å; N421-M431 VanDerWaalsContact OD1-CE 3.27Å; N421-M431 WeakPolarHBondContact OD1-CE 3.46Å
422N78.7Confident80.7Confident88 Ų8857.1 Ų57.147%0.47126%0.263SS..THydrogen-bonded Turntrans-98.215.4176.2-56.7-34.6000111.7R418 K419 V420 F424R418-N422 WeakPolarHBondContact O-CB 3.48Å; R418-N422 VanDerWaalsContact O-CG 3.29Å; R418-N422 PolarHBondContact O-N 2.91Å; R418-N422 PolarHBondContact O-ND2 2.79Å; K419-N422 CarbonylContact O-C 3.39Å; V420-N422 VanDerWaalsContact C-N 3.26Å; V420-N422 PolarHBondContact O-N 3.25Å; N422-F424 PolarHBondContact O-N 3.07Å
423H73.1Confident80.4Confident28 Ų2859.4 Ų59.413%0.1327%0.273CS..  trans-71.7119.7-175.8-155.1-82.5000109.1I388 K419 V420 N421 M425 I426I388-H423 HydrophobicContact CG2-CB 3.97Å; K419-H423 VanDerWaalsContact O-CA 3.27Å; K419-H423 WeakPolarHBondContact O-CA 3.2Å; K419-H423 VanDerWaalsContact O-CB 3.26Å; K419-H423 WeakPolarHBondContact O-CB 3.13Å; K419-H423 PolarHBondContact O-N 3.26Å; V420-H423 WeakPolarHBondContact O-CB 3.48Å; V420-H423 PolarHBondContact O-N 2.96Å; N421-H423 VanDerWaalsContact C-N 3.35Å; H423-M425 WeakPolarHBondContact CE1-CG 3.43Å; H423-M425 PolarHBondContact CE1-SD 3.29Å; H423-M425 WeakPolarHBondContact ND1-CB 3.4Å; H423-M425 WeakPolarHBondContact ND1-CG 3.31Å; H423-M425 PolarHBondContact ND1-N 2.74Å; H423-M425 PolarHBondContact O-N 3.18Å; H423-I426 HydrophobicContact CB-CD1 3.85Å; H423-I426 HydrophobicContact CB-CG1 4.01Å; H423-I426 WeakPolarHBondContact O-CB 3.49Å; H423-I426 PolarHBondContact O-N 3.39Å
424F57.3Low80.2Confident109 Ų10961.1 Ų61.148%0.47828%0.284SS..THydrogen-bonded Turntrans-58.1-23.4-174.867-102.8000113.8P88 A89 N422 I426P88-F424 HydrophobicContact CB-CD2 4.17Å; P88-F424 HydrophobicContact CB-CE2 3.45Å; P88-F424 VanDerWaalsContact CB-CE2 3.45Å; P88-F424 HydrophobicContact CB-CZ 4.43Å; A89-F424 VanDerWaalsContact C-CD2 3.49Å; A89-F424 HydrophobicContact CB-CB 3.69Å; A89-F424 HydrophobicContact CB-CD2 3.75Å; A89-F424 HydrophobicContact CB-CG 4.12Å; A89-F424 WeakPolarHBondContact O-CD2 3.43Å; A89-F424 WeakPolarHBondContact O-CE2 3.31Å; A89-F424 WeakPolarHBondContact O-CG 3.46Å; N422-F424 PolarHBondContact O-N 3.07Å; F424-I426 VanDerWaalsContact C-N 3.29Å; F424-I426 PolarHBondContact O-N 3.01Å
425M50.3Low80Confident5 Ų561.3 Ų61.33%0.02528%0.277CS..THydrogen-bonded Turntrans-76.4-11.3176.4-54.6-17671.400113.7A86 P88 H382 I388 H423A86-M425 CarbonylContact C-O 3.58Å; A86-M425 VanDerWaalsContact C-O 3.24Å; P88-M425 HydrophobicContact CB-CE 3.83Å; P88-M425 HydrophobicContact CB-CG 3.72Å; P88-M425 HydrophobicContact CB-SD 4.22Å; P88-M425 HydrophobicContact CG-CE 3.83Å; H382-M425 HydrophobicContact CB-CE 3.94Å; H382-M425 WeakPolarHBondContact CD2-CE 3.38Å; I388-M425 HydrophobicContact CD1-CB 3.56Å; I388-M425 HydrophobicContact CD1-CG 4.43Å; I388-M425 HydrophobicContact CD1-SD 4.31Å; I388-M425 HydrophobicContact CG1-CB 4.42Å; I388-M425 HydrophobicContact CG1-SD 4.19Å; H423-M425 WeakPolarHBondContact CE1-CG 3.43Å; H423-M425 PolarHBondContact CE1-SD 3.29Å; H423-M425 WeakPolarHBondContact ND1-CB 3.4Å; H423-M425 WeakPolarHBondContact ND1-CG 3.31Å; H423-M425 PolarHBondContact ND1-N 2.74Å; H423-M425 PolarHBondContact O-N 3.18Å
426I55.3Low79.9Confident17 Ų1764.8 Ų64.89%0.08729%0.291CS..  trans-104.5102.3-169.4-63.1-175.5000109.2Y380 I388 V420 H423 F424 N428 Q430Y380-I426 HydrophobicContact CD2-CB 4.28Å; Y380-I426 HydrophobicContact CD2-CD1 4.02Å; Y380-I426 HydrophobicContact CD2-CG1 3.96Å; Y380-I426 HydrophobicContact CD2-CG2 3.54Å; Y380-I426 HydrophobicContact CE2-CG2 3.59Å; Y380-I426 HydrophobicContact CG-CG1 4.33Å; Y380-I426 HydrophobicContact CG-CG2 4.45Å; I388-I426 HydrophobicContact CB-CD1 4.3Å; I388-I426 HydrophobicContact CD1-CD1 4.03Å; I388-I426 HydrophobicContact CD1-CG1 3.56Å; I388-I426 HydrophobicContact CG2-CD1 3.82Å; I388-I426 HydrophobicContact CG2-CG1 4.36Å; V420-I426 HydrophobicContact CG1-CD1 3.85Å; H423-I426 HydrophobicContact CB-CD1 3.85Å; H423-I426 HydrophobicContact CB-CG1 4.01Å; H423-I426 WeakPolarHBondContact O-CB 3.49Å; H423-I426 PolarHBondContact O-N 3.39Å; F424-I426 VanDerWaalsContact C-N 3.29Å; F424-I426 PolarHBondContact O-N 3.01Å; I426-N428 WeakPolarHBondContact CG2-O 3.35Å; I426-Q430 HydrophobicContact CD1-CB 3.64Å; I426-Q430 HydrophobicContact CD1-CG 4.39Å; I426-Q430 HydrophobicContact CG2-CB 3.87Å
427R49.4Very low79.7Confident162 Ų16268 Ų6861%0.61131%0.311SS*.SBendtrans-67.2-40.2-179.3-78.1-178.5-172.1-175.24.8113.1A86A86-R427 HydrophobicContact CB-CB 3.87Å; A86-R427 HydrophobicContact CB-CG 3.49Å; A86-R427 VanDerWaalsContact CB-CG 3.49Å
428N61.5Low79.7Confident112 Ų11267.6 Ų67.660%0.59931%0.309SS*.SBendtrans-108124.8173.8-63.3-40.4000108.2Y380 I426 Q430Y380-N428 VanDerWaalsContact CE2-O 3.28Å; Y380-N428 WeakPolarHBondContact CE2-O 3.37Å; Y380-N428 WeakPolarHBondContact OH-CB 3.29Å; I426-N428 WeakPolarHBondContact CG2-O 3.35Å; N428-Q430 PolarHBondContact O-N 3.24Å; N428-Q430 VanDerWaalsContact O-N 3.14Å
429K71.8Confident79.7Confident166 Ų16665 Ų6572%0.72231%0.31SS*.  trans-45.6120.2-173.2-65.8-175.1177.2-179.10112.3
430Q81.3Confident79.7Confident0 Ų065.3 Ų65.30%031%0.311CS..  trans-97128.3166.5-177.4179.8-31.400107.8A372 Y380 V420 N421 I426 N428A372-Q430 PolarHBondContact O-NE2 3.06Å; Y380-Q430 HydrophobicContact CD2-CB 3.76Å; Y380-Q430 HydrophobicContact CD2-CG 4.26Å; Y380-Q430 HydrophobicContact CE2-CB 3.89Å; V420-Q430 HydrophobicContact CG1-CB 3.96Å; V420-Q430 HydrophobicContact CG1-CG 3.79Å; N421-Q430 VanDerWaalsContact CA-O 3.24Å; N421-Q430 WeakPolarHBondContact CA-O 3.32Å; N421-Q430 PolarHBondContact N-O 3.26Å; I426-Q430 HydrophobicContact CD1-CB 3.64Å; I426-Q430 HydrophobicContact CD1-CG 4.39Å; I426-Q430 HydrophobicContact CG2-CB 3.87Å; N428-Q430 PolarHBondContact O-N 3.24Å; N428-Q430 VanDerWaalsContact O-N 3.14Å
431M91.1Very high80.1Confident66 Ų6669.7 Ų69.733%0.32533%0.328SS..  trans-119.3109.2174.8-1775968.900108.3T373 V374 N417 N421T373-M431 CarbonylContact C-O 3.52Å; T373-M431 VanDerWaalsContact CA-O 3.23Å; T373-M431 WeakPolarHBondContact CA-O 3.48Å; V374-M431 HydrophobicContact CG1-CB 4.17Å; V374-M431 HydrophobicContact CG1-CG 4.09Å; V374-M431 WeakPolarHBondContact CG1-O 3.37Å; V374-M431 HydrophobicContact CG2-CB 4.22Å; V374-M431 PolarHBondContact N-O 3.08Å; N417-M431 HydrophobicContact CB-SD 4.14Å; N421-M431 HydrophobicContact CB-CE 3.53Å; N421-M431 HydrophobicContact CB-SD 4.23Å; N421-M431 VanDerWaalsContact CG-CE 3.42Å; N421-M431 VanDerWaalsContact OD1-CE 3.27Å; N421-M431 WeakPolarHBondContact OD1-CE 3.46Å
432P92.8Very high80.6Confident3 Ų368 Ų682%0.01932%0.319CS..  trans-63.5151.8169.9-13.726.4000111.2M371 A372 Y389 N417 V420M371-P432 CarbonylContact O-C 3.24Å; M371-P432 VanDerWaalsContact O-CA 3.29Å; M371-P432 WeakPolarHBondContact O-CA 3.3Å; M371-P432 WeakPolarHBondContact O-CB 3.1Å; A372-P432 WeakPolarHBondContact O-CA 3.43Å; Y389-P432 HydrophobicContact CD2-CB 3.92Å; Y389-P432 HydrophobicContact CD2-CG 3.9Å; Y389-P432 HydrophobicContact CE2-CB 3.83Å; Y389-P432 HydrophobicContact CE2-CG 4.25Å; N417-P432 PolarHBondContact ND2-O 3.49Å; N417-P432 WeakPolarHBondContact OD1-CB 3.47Å; N417-P432 PolarHBondContact OD1-O 2.67Å; V420-P432 HydrophobicContact CB-CG 3.53Å; V420-P432 HydrophobicContact CG1-CG 3.62Å; V420-P432 HydrophobicContact CG2-CG 3.76Å
433E90.4Very high81.3Confident52 Ų5264.6 Ų64.624%0.24330%0.301CS..EExtended strand (participates in β ladder)trans-126.7100-176-167.5-172.4-157.300110M371 V374 P375 K435M371-E433 HydrophobicContact CB-CB 4.28Å; M371-E433 WeakPolarHBondContact CB-O 3.48Å; M371-E433 PolarHBondContact N-O 3Å; M371-E433 PolarHBondContact O-N 2.84Å; V374-E433 HydrophobicContact CG1-CB 3.85Å; V374-E433 HydrophobicContact CG1-CG 4.22Å; P375-E433 WeakPolarHBondContact CD-OE2 3.44Å; E433-K435 WeakPolarHBondContact OE1-CE 3.49Å; E433-K435 IonicContact OE1-NZ 2.6Å; E433-K435 WeakPolarHBondContact OE2-CE 2.87Å; E433-K435 IonicContact OE2-NZ 2.69Å; E433-K435 PolarHBondContact OE2-NZ 2.99Å
434P92.4Very high82.4Confident37 Ų3763.9 Ų63.924%0.2430%0.298CS..EExtended strand (participates in β ladder)trans-80129.2169.431.4-32.5000111I369 L413 N417I369-P434 CarbonylContact O-C 3.44Å; I369-P434 VanDerWaalsContact O-CA 3.31Å; I369-P434 WeakPolarHBondContact O-CA 3.47Å; L413-P434 HydrophobicContact CB-CB 4.31Å; L413-P434 HydrophobicContact CB-CG 4.48Å; L413-P434 HydrophobicContact CD1-CB 3.95Å; N417-P434 WeakPolarHBondContact ND2-CD 3.47Å
435K92.1Very high84Confident96 Ų9661.7 Ų61.742%0.41729%0.287SS..EExtended strand (participates in β ladder)trans-120.5136.8170.4-63.6178-174.2164.80108.7I369 E433I369-K435 HydrophobicContact CB-CB 4.45Å; I369-K435 PolarHBondContact N-O 3.5Å; I369-K435 PolarHBondContact O-N 3.48Å; E433-K435 WeakPolarHBondContact OE1-CE 3.49Å; E433-K435 IonicContact OE1-NZ 2.6Å; E433-K435 WeakPolarHBondContact OE2-CE 2.87Å; E433-K435 IonicContact OE2-NZ 2.69Å; E433-K435 PolarHBondContact OE2-NZ 2.99Å
436Y94.1Very high86.1Confident131 Ų13163.4 Ų63.451%0.51429%0.294SS..EExtended strand (participates in β ladder)trans-149151.9-175.364.6-86.6000113.8I367 L410 L438I367-Y436 CarbonylContact O-C 3.51Å; I367-Y436 VanDerWaalsContact O-CA 3.26Å; I367-Y436 WeakPolarHBondContact O-CA 3.32Å; L410-Y436 HydrophobicContact CD1-CD1 4.33Å; L410-Y436 HydrophobicContact CD1-CD2 4.04Å; L410-Y436 HydrophobicContact CD1-CE1 3.96Å; L410-Y436 HydrophobicContact CD1-CE2 3.63Å; L410-Y436 HydrophobicContact CD1-CG 4.38Å; L410-Y436 HydrophobicContact CD2-CD1 3.6Å; L410-Y436 HydrophobicContact CD2-CD2 4.29Å; L410-Y436 HydrophobicContact CD2-CE1 3.89Å; L410-Y436 HydrophobicContact CD2-CG 3.83Å; Y436-L438 HydrophobicContact CD2-CB 4.41Å
437T93.5Very high87.7Confident67 Ų6765.3 Ų65.341%0.41131%0.307SS..  trans-127.722.3167.859.70000110.5D364 D366 I367 T439D364-T437 WeakPolarHBondContact O-CB 3.47Å; D364-T437 PolarHBondContact O-OG1 3.3Å; D366-T437 PolarHBondContact N-O 3.44Å; I367-T437 PolarHBondContact N-OG1 3.45Å; I367-T437 VanDerWaalsContact N-OG1 3.15Å; I367-T437 PolarHBondContact O-N 3.03Å; T437-T439 PolarHBondContact O-N 3.27Å
438L93.1Very high88.8Confident23 Ų2366.2 Ų66.212%0.1232%0.318CS..  trans-55.8133.2172.3-65.1-180000110.4Y204 P320 L368 I409 Y436Y204-L438 HydrophobicContact CE2-CB 4.33Å; Y204-L438 HydrophobicContact CE2-CD2 4Å; P320-L438 HydrophobicContact CB-CD2 4.09Å; L368-L438 HydrophobicContact CB-CD1 4.07Å; L368-L438 HydrophobicContact CB-CD2 4.33Å; L368-L438 HydrophobicContact CB-CG 4.16Å; L368-L438 HydrophobicContact CD2-CD1 4.19Å; I409-L438 HydrophobicContact CG2-CD1 3.66Å; Y436-L438 HydrophobicContact CD2-CB 4.41Å
439T91.4Very high88.4Confident99 Ų9969 Ų6961%0.60733%0.332SS*.  trans-101-16-177.559.60000112.8Y204 D366 T437Y204-T439 PolarHBondContact OH-N 3.34Å; Y204-T439 PolarHBondContact OH-OG1 3.5Å; D366-T439 PolarHBondContact OD1-OG1 3.02Å; T437-T439 PolarHBondContact O-N 3.27Å
440K92.1Very high87Confident72 Ų7266.5 Ų66.531%0.31334%0.335SS..SBendtrans-132164.9177.1-56.3-173.3-174.8-1630111.2D201 Y204 L442D201-K440 WeakPolarHBondContact O-CD 3.39Å; D201-K440 WeakPolarHBondContact OD1-CE 3.35Å; D201-K440 IonicContact OD1-NZ 3.32Å; D201-K440 PolarHBondContact OD1-NZ 3.04Å; Y204-K440 HydrophobicContact CD1-CB 4.25Å; Y204-K440 HydrophobicContact CD1-CD 4.37Å; Y204-K440 HydrophobicContact CD2-CB 3.71Å; Y204-K440 HydrophobicContact CE1-CB 4.21Å; Y204-K440 HydrophobicContact CE1-CG 4.39Å; Y204-K440 HydrophobicContact CE2-CB 3.68Å; Y204-K440 WeakPolarHBondContact CE2-O 3.4Å; Y204-K440 HydrophobicContact CG-CB 4.01Å; K440-L442 PolarHBondContact O-N 3.17Å
441R94.6Very high85Confident92 Ų9269.9 Ų69.935%0.34737%0.37SS..BIsolated β-bridgetrans-73.3125.8174-63.7-18071.5-162.2-3.4109.7E202 F203 Y204 D408E202-R441 HydrophobicContact CG-CG 4.39Å; E202-R441 WeakPolarHBondContact O-CB 3.35Å; E202-R441 PolarHBondContact O-N 2.85Å; E202-R441 WeakPolarHBondContact OE1-CD 3.48Å; E202-R441 IonicContact OE1-CZ 3.4Å; E202-R441 IonicContact OE1-NE 3.54Å; E202-R441 IonicContact OE1-NH1 2.88Å; E202-R441 PolarHBondContact OE1-NH1 2.68Å; F203-R441 VanDerWaalsContact CA-O 3.28Å; F203-R441 WeakPolarHBondContact CA-O 3.35Å; F203-R441 HydrophobicContact CD1-CB 3.59Å; F203-R441 HydrophobicContact CE1-CB 3.7Å; F203-R441 HydrophobicContact CG-CB 4.36Å; Y204-R441 PolarHBondContact N-O 3.33Å; D408-R441 HydrophobicContact CB-CB 4.21Å; D408-R441 IonicContact OD2-CZ 2.67Å; D408-R441 IonicContact OD2-NE 3.99Å; D408-R441 PolarHBondContact OD2-NE 3Å; D408-R441 IonicContact OD2-NH2 3.71Å; D408-R441 PolarHBondContact OD2-NH2 2.66Å; D408-R441 VanDerWaalsContact OD2-NH2 3.07Å
442L95.8Very high82.1Confident3 Ų372.8 Ų72.82%0.01639%0.392CS..  trans-101.2118.9176.8179.462.3000109.8Y204 L206 P320 L322 D408 I409 K440Y204-L442 HydrophobicContact CD2-CB 3.92Å; Y204-L442 HydrophobicContact CD2-CD1 4.23Å; L206-L442 HydrophobicContact CD1-CD1 3.86Å; L206-L442 HydrophobicContact CD2-CD1 4.3Å; L206-L442 HydrophobicContact CG-CD1 4.29Å; P320-L442 HydrophobicContact CB-CD1 4.42Å; P320-L442 HydrophobicContact CB-CD2 4.01Å; P320-L442 HydrophobicContact CG-CD1 3.97Å; P320-L442 HydrophobicContact CG-CD2 4.36Å; L322-L442 HydrophobicContact CD1-CD2 3.82Å; L322-L442 HydrophobicContact CD2-CD2 3.63Å; L322-L442 HydrophobicContact CG-CD2 4.28Å; D408-L442 CarbonylContact C-O 3.1Å; D408-L442 VanDerWaalsContact CA-O 3.25Å; D408-L442 WeakPolarHBondContact CA-O 3.45Å; I409-L442 HydrophobicContact CB-CB 4.23Å; I409-L442 HydrophobicContact CB-CD2 4.35Å; I409-L442 HydrophobicContact CB-CG 4.44Å; I409-L442 HydrophobicContact CG2-CB 3.78Å; I409-L442 HydrophobicContact CG2-CD2 4.22Å; I409-L442 HydrophobicContact CG2-CG 4.39Å; I409-L442 PolarHBondContact N-O 3.15Å; K440-L442 PolarHBondContact O-N 3.17Å
443V95.2Very high79.3Confident17 Ų1778.5 Ų78.510%0.10343%0.426CS..  trans-117.6119.5176-179.90000108.8F203 D408 R445F203-V443 HydrophobicContact CD1-CG2 3.82Å; F203-V443 HydrophobicContact CE1-CG2 3.76Å; D408-V443 HydrophobicContact CB-CG2 4.32Å; V443-R445 HydrophobicContact CG1-CG 4.17Å
444L94.8Very high76.5Confident12 Ų1280.6 Ų80.66%0.06344%0.444CS..  trans-94.3122176.8-64.9173.1000109.9L206 F247 F249 L397 I409L206-L444 HydrophobicContact CD1-CD2 3.72Å; F247-L444 HydrophobicContact CD1-CB 3.96Å; F247-L444 HydrophobicContact CE1-CB 3.74Å; F247-L444 HydrophobicContact CE2-CB 4.42Å; F247-L444 HydrophobicContact CG-CB 4.42Å; F247-L444 HydrophobicContact CZ-CB 4Å; F249-L444 HydrophobicContact CE2-CD2 4.18Å; F249-L444 HydrophobicContact CZ-CD2 4.47Å; L397-L444 HydrophobicContact CD2-CD1 3.88Å; I409-L444 HydrophobicContact CD1-CD1 4.27Å
445R92.2Very high74Confident64 Ų6485.3 Ų85.324%0.24247%0.472CS..  trans-122.3147.4179.1-67.5-63.6-165.9178.5-0.5110.7R211 F247 A400 A401 S403 K405 V443R211-R445 PolarHBondContact NH1-O 3.03Å; R211-R445 PolarHBondContact NH2-O 3Å; F247-R445 WeakPolarHBondContact CD1-O 3.49Å; A400-R445 PolarHBondContact O-NH1 3.39Å; A401-R445 PolarHBondContact O-NH1 3.22Å; S403-R445 PolarHBondContact O-NH1 3.44Å; K405-R445 PolarHBondContact O-NH2 2.84Å; V443-R445 HydrophobicContact CG1-CG 4.17Å
446F93.6Very high71.9Confident41 Ų4194.4 Ų94.418%0.1851%0.506CS..PPolyproline II helixtrans-62.8143.6171.3-62.8-41.4000111.1L243 R246 F247 E398 A401 N402L243-F446 HydrophobicContact CD1-CE1 3.95Å; L243-F446 HydrophobicContact CD1-CZ 4.22Å; R246-F446 HydrophobicContact CB-CD1 3.56Å; R246-F446 HydrophobicContact CB-CE1 3.78Å; R246-F446 HydrophobicContact CB-CG 4.42Å; R246-F446 VanDerWaalsContact NH2-CZ 3.3Å; R246-F446 WeakPolarHBondContact O-CA 3.18Å; F247-F446 AromaticContact CD1-CD1 3.71Å; F247-F446 HydrophobicContact CD1-CD1 3.71Å; F247-F446 AromaticContact CD1-CE1 3.94Å; F247-F446 HydrophobicContact CD1-CE1 3.94Å; F247-F446 AromaticContact CE1-CD1 3.71Å; F247-F446 HydrophobicContact CE1-CD1 3.71Å; F247-F446 AromaticContact CE1-CE1 3.6Å; F247-F446 HydrophobicContact CE1-CE1 3.6Å; F247-F446 HydrophobicContact CE1-CZ 4.46Å; F247-F446 HydrophobicContact CE2-CE1 4.45Å; F247-F446 HydrophobicContact CG-CD1 4.43Å; F247-F446 HydrophobicContact CG-CE1 4.49Å; F247-F446 HydrophobicContact CZ-CD1 4.43Å; F247-F446 AromaticContact CZ-CE1 3.87Å; F247-F446 HydrophobicContact CZ-CE1 3.87Å; E398-F446 HydrophobicContact CB-CZ 4.23Å; E398-F446 HydrophobicContact CG-CE2 4.34Å; E398-F446 HydrophobicContact CG-CZ 3.94Å; A401-F446 HydrophobicContact CB-CD1 4.11Å; A401-F446 HydrophobicContact CB-CD2 3.79Å; A401-F446 HydrophobicContact CB-CE1 3.85Å; A401-F446 HydrophobicContact CB-CE2 3.49Å; A401-F446 VanDerWaalsContact CB-CE2 3.49Å; A401-F446 HydrophobicContact CB-CG 4.09Å; A401-F446 HydrophobicContact CB-CZ 3.55Å; N402-F446 VanDerWaalsContact OD1-CE2 3.31Å; N402-F446 WeakPolarHBondContact OD1-CE2 3.41Å
447V89.8Confident70.8Confident57 Ų5792.6 Ų92.635%0.34551%0.506SS..PPolyproline II helixtrans-77.6128.1171.5-175.60000107.2R246 L449R246-V447 PolarHBondContact O-N 3.31Å; V447-L449 PolarHBondContact O-N 3.13Å; V447-L449 VanDerWaalsContact O-N 3.16Å
448E72.3Confident69.6Low180 Ų18093.9 Ų93.984%0.84151%0.511SS*.PPolyproline II helixtrans-64.4116.7171.6-67.2-175.1173.600108.3S450E448-S450 PolarHBondContact O-N 3.38Å
449L52.9Low68.2Low171 Ų17197.9 Ų97.990%0.89553%0.532SS*.  trans-65107.5169.1-69.8168.6000106.3V447 G451V447-L449 PolarHBondContact O-N 3.13Å; V447-L449 VanDerWaalsContact O-N 3.16Å; L449-G451 PolarHBondContact O-N 2.8Å
450S42.8Very low66.9Low114 Ų11497.8 Ų97.880%0.79753%0.528SS*.  trans-64.979.3172.356.30000109.5E448 T452E448-S450 PolarHBondContact O-N 3.38Å; S450-T452 VanDerWaalsContact C-N 3.33Å; S450-T452 PolarHBondContact O-N 3.03Å
451G37.5Very low65.3Low70 Ų7099.4 Ų99.472%0.72254%0.542SS*.  trans-87.469.1172.200000110.3L449 V453L449-G451 PolarHBondContact O-N 2.8Å; G451-V453 PolarHBondContact O-N 3.17Å
452T31.9Very low63.4Low128 Ų12899.9 Ų99.979%0.78555%0.554SS**  trans-8296.2155.944.90000107.4S450 P454S450-T452 VanDerWaalsContact C-N 3.33Å; S450-T452 PolarHBondContact O-N 3.03Å; T452-P454 WeakPolarHBondContact O-CD 3.44Å
453V32Very low61Low123 Ų123106.9 Ų106.975%0.74559%0.593SS**  trans-76.1113.7153.3-178.40000105.2G451 T455G451-V453 PolarHBondContact O-N 3.17Å; V453-T455 PolarHBondContact O-N 3.27Å; V453-T455 VanDerWaalsContact O-N 3.1Å
454P33.6Very low58.4Low95 Ų95113.8 Ų113.862%0.61763%0.631SS**  trans-70.8109.4171.520.5-12.9000107T452 Y456T452-P454 WeakPolarHBondContact O-CD 3.44Å; P454-Y456 HydrophobicContact CB-CD2 4.16Å; P454-Y456 HydrophobicContact CB-CE2 4.04Å; P454-Y456 PolarHBondContact O-N 2.89Å
455T38.7Very low55.4Low137 Ų137122.3 Ų122.384%0.8468%0.678SS**  trans-69104.7159.748.80000106.9V453V453-T455 PolarHBondContact O-N 3.27Å; V453-T455 VanDerWaalsContact O-N 3.1Å
456Y47.4Very low52Low287 Ų287127.5 Ų127.5100%1.12572%0.718SS**  trans-91.80158.3-81.2-75.8000109.5P454P454-Y456 HydrophobicContact CB-CD2 4.16Å; P454-Y456 HydrophobicContact CB-CE2 4.04Å; P454-Y456 PolarHBondContact O-N 2.89Å

Retrieved 456 of 456 residues in 343 ms (Link to these results)