A0A087YAG4_POEFO Loading...

Alpha-1A adrenergic receptor

AlphaFold DB , UniProt , Accession A0A087YAG4, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 480 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37.2	Very low	37.3	Very low	255 Å²	255	139.4 Å²	139.4	100%	1.256	83%	0.83	S	S	*	*				0	109.6	0	-104.8	162.7	179.2	0	0	107.9
2	G	33	Very low	37.5	Very low	71 Å²	71	136.6 Å²	136.6	73%	0.732	82%	0.822	S	S	*	*			trans	-171.7	102.9	174.9	0	0	0	0	0	106.7
3	P	44.7	Very low	37.5	Very low	133 Å²	133	137.4 Å²	137.4	86%	0.864	82%	0.818	S	S	*	*			trans	-86.6	152.1	-174	33.4	-30.7	0	0	0	111.9
4	V	40.6	Very low	37.9	Very low	128 Å²	128	137.1 Å²	137.1	78%	0.776	82%	0.819	S	S	*	*			trans	-90	145.5	165.6	176.3	0	0	0	0	108.5
5	L	39	Very low	38.3	Very low	147 Å²	147	138.2 Å²	138.2	77%	0.77	81%	0.812	S	S	*	*			trans	144.2	145	154.2	-107	73.3	0	0	0	108.7
6	D	35	Very low	38.6	Very low	125 Å²	125	139.4 Å²	139.4	67%	0.668	81%	0.813	S	S	*	*			cis	-172.9	157.8	-10.5	-121	-3.7	0	0	0	106.9
7	N	35.3	Very low	39.2	Very low	143 Å²	143	136.6 Å²	136.6	77%	0.765	80%	0.802	S	S	*	*			trans	30.4	125.5	149.2	-86.5	-16.5	0	0	0	122.3
8	M	30.8	Very low	40	Very low	179 Å²	179	137.1 Å²	137.1	88%	0.882	81%	0.807	S	S	*	*				-175.5	133.2	108.8	-140.4	83.4	-167.8	0	0	111.2
9	T	37.2	Very low	40.6	Very low	129 Å²	129	137.9 Å²	137.9	79%	0.791	81%	0.808	S	S	*	*			trans	-82.8	-171.8	166.1	49	0	0	0	0	111
10	P	44.2	Very low	41.1	Very low	124 Å²	124	134.8 Å²	134.8	81%	0.805	79%	0.792	S	S	*	*				-106.7	125.8	-95.6	31.4	-12.5	0	0	0	112.2
11	A	33.4	Very low	41.5	Very low	99 Å²	99	133 Å²	133	82%	0.818	79%	0.788	S	S	*	*			trans	-92.7	120	172.6	0	0	0	0	0	111	L13	A11-L13 PolarHBondContact O-N 3.48Å
12	S	39.6	Very low	42.1	Very low	106 Å²	106	128.2 Å²	128.2	74%	0.741	76%	0.762	S	S	*	*			trans	-39.6	115.1	168	49	0	0	0	0	114.2
13	L	37	Very low	43.1	Very low	147 Å²	147	131.3 Å²	131.3	77%	0.77	76%	0.76	S	S	*	*			trans	-104.1	70.7	162	-144.1	92.6	0	0	0	109.6	A11 Q15	A11-L13 PolarHBondContact O-N 3.48Å; L13-Q15 HydrophobicContact CD2-CB 4.36Å; L13-Q15 PolarHBondContact O-N 3.41Å
14	T	43.7	Very low	43.3	Very low	134 Å²	134	133.1 Å²	133.1	82%	0.822	76%	0.755	S	S	*	*			trans	-72.6	87.1	156.7	38.6	0	0	0	0	107.6
15	Q	44.3	Very low	44	Very low	153 Å²	153	134.1 Å²	134.1	72%	0.715	75%	0.749	S	S	*	*			trans	-91.7	117.6	170.4	-160.7	167.2	4.7	0	0	108.8	L13 C17	L13-Q15 HydrophobicContact CD2-CB 4.36Å; L13-Q15 PolarHBondContact O-N 3.41Å; Q15-C17 PolarHBondContact O-N 3.33Å; Q15-C17 VanDerWaalsContact O-N 3.07Å
16	N	42	Very low	45	Very low	157 Å²	157	130.7 Å²	130.7	84%	0.84	74%	0.736	S	S	*	*			trans	-53.3	106.2	172.8	-82.4	-24.9	0	0	0	110.9
17	C	49	Very low	46.3	Very low	92 Å²	92	131.3 Å²	131.3	62%	0.622	73%	0.734	S	S	*	*			trans	-94.2	104.4	164.2	-84.5	0	0	0	0	109.4	Q15 N19 C20	Q15-C17 PolarHBondContact O-N 3.33Å; Q15-C17 VanDerWaalsContact O-N 3.07Å; C17-N19 PolarHBondContact O-N 2.97Å; C17-C20 WeakPolarHBondContact CB-SG 3.47Å
18	T	54.3	Low	47.6	Very low	146 Å²	146	129.8 Å²	129.8	90%	0.896	73%	0.726	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.9	10.7	172.7	35.9	0	0	0	0	113.6
19	N	51	Low	49.9	Very low	153 Å²	153	130.1 Å²	130.1	82%	0.818	72%	0.717	S	S	*	*	T	Hydrogen-bonded Turn	trans	-144.3	57.8	170.9	-142.1	-4.9	0	0	0	110.5	C17 S21	C17-N19 PolarHBondContact O-N 2.97Å; N19-S21 PolarHBondContact O-N 3.43Å; N19-S21 VanDerWaalsContact O-N 3.1Å
20	C	51.8	Low	52.2	Low	74 Å²	74	128.3 Å²	128.3	50%	0.5	71%	0.705	S	S	.	*			trans	-69.3	100.4	170.6	-85.2	0	0	0	0	109.3	C17 H22	C17-C20 WeakPolarHBondContact CB-SG 3.47Å; C20-H22 HydrophobicContact CB-CB 4.06Å; C20-H22 PolarHBondContact O-N 3.27Å
21	S	47.9	Very low	54.2	Low	99 Å²	99	126.6 Å²	126.6	69%	0.692	69%	0.693	S	S	*	*			trans	-65.2	13.8	154.7	29.9	0	0	0	0	112.9	N19 I23	N19-S21 PolarHBondContact O-N 3.43Å; N19-S21 VanDerWaalsContact O-N 3.1Å; S21-I23 PolarHBondContact O-N 3.22Å
22	H	51.4	Low	56.7	Low	154 Å²	154	128.6 Å²	128.6	71%	0.713	68%	0.683	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.2	99.3	164.8	-84.5	-109.3	0	0	0	109.6	C20	C20-H22 HydrophobicContact CB-CB 4.06Å; C20-H22 PolarHBondContact O-N 3.27Å
23	I	52.8	Low	59	Low	136 Å²	136	125.8 Å²	125.8	70%	0.697	66%	0.662	S	S	*	*	T	Hydrogen-bonded Turn	trans	176.2	-3.5	142.5	-86.2	151.9	0	0	0	111.4	S21	S21-I23 PolarHBondContact O-N 3.22Å
24	F	49.4	Very low	61.5	Low	171 Å²	171	123 Å²	123	75%	0.75	65%	0.651	S	S	*	*	H	α-helix	trans	-84.1	-13	175.4	-121.2	-93	0	0	0	115.6	L28	F24-L28 WeakPolarHBondContact O-CB 3.5Å; F24-L28 PolarHBondContact O-N 3.24Å
25	F	55.9	Low	63.8	Low	148 Å²	148	118.8 Å²	118.8	65%	0.649	63%	0.629	S	S	*	*	H	α-helix	trans	-83.8	-35.4	-176.7	-69.2	-79.3	0	0	0	116.8	R29	F25-R29 VanDerWaalsContact O-CB 3.27Å; F25-R29 WeakPolarHBondContact O-CB 3.26Å; F25-R29 PolarHBondContact O-N 3.35Å; F25-R29 VanDerWaalsContact O-N 3.14Å
26	P	58.5	Low	65.9	Low	76 Å²	76	114.4 Å²	114.4	49%	0.494	61%	0.61	S	S	.	*	H	α-helix	trans	-72.2	-42.7	177.3	24.7	-29.8	0	0	0	112	R29 V30	P26-R29 PolarHBondContact O-N 3.49Å; P26-V30 VanDerWaalsContact O-CG2 3.25Å; P26-V30 WeakPolarHBondContact O-CG2 3.05Å; P26-V30 PolarHBondContact O-N 3.38Å
27	E	62	Low	68.3	Low	138 Å²	138	108 Å²	108	65%	0.645	58%	0.581	S	S	*	*	H	α-helix	trans	-57.9	-51.3	175.2	-73	-93.3	149.9	0	0	111.3	R29 V30 V31	E27-R29 VanDerWaalsContact C-N 3.3Å; E27-R29 PolarHBondContact O-N 3.15Å; E27-V30 PolarHBondContact O-N 3.47Å; E27-V31 WeakPolarHBondContact O-CB 3.04Å; E27-V31 VanDerWaalsContact O-CG2 3.28Å; E27-V31 WeakPolarHBondContact O-CG2 3.2Å; E27-V31 PolarHBondContact O-N 3.33Å
28	L	64.1	Low	70.4	Confident	111 Å²	111	109.6 Å²	109.6	58%	0.581	58%	0.581	S	S	*	*	H	α-helix	trans	-63.7	-34.8	179.6	-172.3	65.2	0	0	0	112.4	F24 K32	F24-L28 WeakPolarHBondContact O-CB 3.5Å; F24-L28 PolarHBondContact O-N 3.24Å; L28-K32 VanDerWaalsContact O-CB 3.22Å; L28-K32 WeakPolarHBondContact O-CB 3.06Å; L28-K32 PolarHBondContact O-N 3.49Å
29	R	78.8	Confident	72.2	Confident	186 Å²	186	108 Å²	108	70%	0.702	57%	0.566	S	S	*	*	H	α-helix	trans	-69	-44	175.2	-170	-178.8	-66.9	-162.8	-1.5	111.1	F25 P26 E27 K32 T33	F25-R29 VanDerWaalsContact O-CB 3.27Å; F25-R29 WeakPolarHBondContact O-CB 3.26Å; F25-R29 PolarHBondContact O-N 3.35Å; F25-R29 VanDerWaalsContact O-N 3.14Å; P26-R29 PolarHBondContact O-N 3.49Å; E27-R29 VanDerWaalsContact C-N 3.3Å; E27-R29 PolarHBondContact O-N 3.15Å; R29-K32 PolarHBondContact O-N 3.46Å; R29-T33 WeakPolarHBondContact O-CB 3.18Å; R29-T33 PolarHBondContact O-N 3.42Å; R29-T33 PolarHBondContact O-OG1 3.16Å
30	V	84.3	Confident	74.2	Confident	90 Å²	90	101.5 Å²	101.5	55%	0.545	53%	0.531	S	S	.	.	H	α-helix	trans	-64.3	-46.4	176.9	173.3	0	0	0	0	110.8	P26 E27 K32 T33 V34	P26-V30 VanDerWaalsContact O-CG2 3.25Å; P26-V30 WeakPolarHBondContact O-CG2 3.05Å; P26-V30 PolarHBondContact O-N 3.38Å; E27-V30 PolarHBondContact O-N 3.47Å; V30-K32 VanDerWaalsContact C-N 3.34Å; V30-K32 PolarHBondContact O-N 3.46Å; V30-T33 PolarHBondContact O-N 3.44Å; V30-V34 HydrophobicContact CG1-CG2 4.19Å; V30-V34 WeakPolarHBondContact O-CB 3.05Å; V30-V34 VanDerWaalsContact O-CG2 3.27Å; V30-V34 WeakPolarHBondContact O-CG2 3.28Å; V30-V34 PolarHBondContact O-N 3.49Å
31	V	87.1	Confident	76.1	Confident	89 Å²	89	99.7 Å²	99.7	54%	0.539	53%	0.525	S	S	.	.	H	α-helix	trans	-60.5	-43.9	176.7	173.9	0	0	0	0	110.9	E27 V34 A35	E27-V31 WeakPolarHBondContact O-CB 3.04Å; E27-V31 VanDerWaalsContact O-CG2 3.28Å; E27-V31 WeakPolarHBondContact O-CG2 3.2Å; E27-V31 PolarHBondContact O-N 3.33Å; V31-V34 PolarHBondContact O-N 2.72Å; V31-A35 WeakPolarHBondContact O-CB 3.21Å; V31-A35 PolarHBondContact O-N 2.78Å
32	K	86.2	Confident	78.3	Confident	140 Å²	140	99.4 Å²	99.4	61%	0.609	52%	0.519	S	S	*	.	H	α-helix	trans	-60.3	-46.4	174.5	-179.2	-175.7	173.4	-173.5	0	111.7	L28 R29 V30 A35 L36	L28-K32 VanDerWaalsContact O-CB 3.22Å; L28-K32 WeakPolarHBondContact O-CB 3.06Å; L28-K32 PolarHBondContact O-N 3.49Å; R29-K32 PolarHBondContact O-N 3.46Å; V30-K32 VanDerWaalsContact C-N 3.34Å; V30-K32 PolarHBondContact O-N 3.46Å; K32-A35 PolarHBondContact O-N 3.36Å; K32-L36 HydrophobicContact CG-CD1 3.95Å; K32-L36 HydrophobicContact CG-CG 4.49Å; K32-L36 WeakPolarHBondContact O-CB 3.26Å; K32-L36 VanDerWaalsContact O-CG 3.27Å; K32-L36 WeakPolarHBondContact O-CG 3.29Å; K32-L36 PolarHBondContact O-N 2.82Å
33	T	87.3	Confident	80.2	Confident	48 Å²	48	93.5 Å²	93.5	29%	0.294	49%	0.491	S	S	.	.	H	α-helix	trans	-65.1	-43.6	180	-62.5	0	0	0	0	111.8	R29 V30 L36 G37 I95	R29-T33 WeakPolarHBondContact O-CB 3.18Å; R29-T33 PolarHBondContact O-N 3.42Å; R29-T33 PolarHBondContact O-OG1 3.16Å; V30-T33 PolarHBondContact O-N 3.44Å; T33-L36 PolarHBondContact O-N 2.89Å; T33-G37 PolarHBondContact O-N 2.94Å; T33-I95 HydrophobicContact CG2-CG2 3.57Å
34	V	90.5	Very high	82.2	Confident	89 Å²	89	88.3 Å²	88.3	54%	0.539	46%	0.464	S	S	.	.	H	α-helix	trans	-64.9	-45.3	176	172.4	0	0	0	0	110.4	V30 V31 G37 M38	V30-V34 HydrophobicContact CG1-CG2 4.19Å; V30-V34 WeakPolarHBondContact O-CB 3.05Å; V30-V34 VanDerWaalsContact O-CG2 3.27Å; V30-V34 WeakPolarHBondContact O-CG2 3.28Å; V30-V34 PolarHBondContact O-N 3.49Å; V31-V34 PolarHBondContact O-N 2.72Å; V34-G37 PolarHBondContact O-N 2.99Å; V34-M38 HydrophobicContact CG1-CG 4.41Å; V34-M38 WeakPolarHBondContact O-CB 3.17Å; V34-M38 VanDerWaalsContact O-CG 3.28Å; V34-M38 WeakPolarHBondContact O-CG 3.46Å; V34-M38 PolarHBondContact O-N 3.11Å
35	A	90.8	Very high	84.4	Confident	45 Å²	45	85.5 Å²	85.5	37%	0.372	46%	0.457	S	S	.	.	H	α-helix	trans	-61	-46.3	177.1	0	0	0	0	0	111.8	V31 K32 M38 I39	V31-A35 WeakPolarHBondContact O-CB 3.21Å; V31-A35 PolarHBondContact O-N 2.78Å; K32-A35 PolarHBondContact O-N 3.36Å; A35-M38 PolarHBondContact O-N 3.03Å; A35-I39 WeakPolarHBondContact O-CD1 3.3Å; A35-I39 VanDerWaalsContact O-CG1 3.25Å; A35-I39 WeakPolarHBondContact O-CG1 3.32Å; A35-I39 PolarHBondContact O-N 2.72Å
36	L	89.6	Confident	86.2	Confident	60 Å²	60	82.9 Å²	82.9	31%	0.314	45%	0.445	S	S	.	.	H	α-helix	trans	-60.6	-46.2	174.8	-75.9	169.8	0	0	0	111.4	K32 T33 M38 I39 L40	K32-L36 HydrophobicContact CG-CD1 3.95Å; K32-L36 HydrophobicContact CG-CG 4.49Å; K32-L36 WeakPolarHBondContact O-CB 3.26Å; K32-L36 VanDerWaalsContact O-CG 3.27Å; K32-L36 WeakPolarHBondContact O-CG 3.29Å; K32-L36 PolarHBondContact O-N 2.82Å; T33-L36 PolarHBondContact O-N 2.89Å; L36-M38 VanDerWaalsContact C-N 3.33Å; L36-M38 PolarHBondContact O-N 3.31Å; L36-I39 PolarHBondContact O-N 3.33Å; L36-L40 WeakPolarHBondContact O-CB 3.36Å; L36-L40 VanDerWaalsContact O-CG 3.28Å; L36-L40 WeakPolarHBondContact O-CG 3.35Å; L36-L40 PolarHBondContact O-N 2.78Å
37	G	91.9	Very high	87.8	Confident	22 Å²	22	79.2 Å²	79.2	23%	0.227	42%	0.422	C	S	.	.	H	α-helix	trans	-59.7	-40.9	176.9	0	0	0	0	0	113	T33 V34 G41	T33-G37 PolarHBondContact O-N 2.94Å; V34-G37 PolarHBondContact O-N 2.99Å; G37-G41 PolarHBondContact O-N 3.19Å
38	M	92.7	Very high	89.4	Confident	127 Å²	127	74.3 Å²	74.3	63%	0.626	40%	0.401	S	S	*	.	H	α-helix	trans	-65	-45.5	175	-72	-63	-65.7	0	0	112	V34 A35 L36 G41 V42	V34-M38 HydrophobicContact CG1-CG 4.41Å; V34-M38 WeakPolarHBondContact O-CB 3.17Å; V34-M38 VanDerWaalsContact O-CG 3.28Å; V34-M38 WeakPolarHBondContact O-CG 3.46Å; V34-M38 PolarHBondContact O-N 3.11Å; A35-M38 PolarHBondContact O-N 3.03Å; L36-M38 VanDerWaalsContact C-N 3.33Å; L36-M38 PolarHBondContact O-N 3.31Å; M38-G41 PolarHBondContact O-N 2.85Å; M38-V42 WeakPolarHBondContact O-CG2 3.26Å; M38-V42 PolarHBondContact O-N 3.29Å
39	I	92.7	Very high	90.8	Very high	112 Å²	112	72.2 Å²	72.2	57%	0.574	39%	0.393	S	S	*	.	H	α-helix	trans	-61.8	-49.4	178.7	-68.8	164.1	0	0	0	110.5	A35 L36 G41 V42 F43	A35-I39 WeakPolarHBondContact O-CD1 3.3Å; A35-I39 VanDerWaalsContact O-CG1 3.25Å; A35-I39 WeakPolarHBondContact O-CG1 3.32Å; A35-I39 PolarHBondContact O-N 2.72Å; L36-I39 PolarHBondContact O-N 3.33Å; I39-G41 PolarHBondContact O-N 3.11Å; I39-V42 PolarHBondContact O-N 3.4Å; I39-F43 WeakPolarHBondContact O-CB 3.32Å; I39-F43 PolarHBondContact O-N 2.83Å
40	L	91.8	Very high	91.5	Very high	16 Å²	16	63.7 Å²	63.7	8%	0.084	36%	0.362	C	S	.	.	H	α-helix	trans	-66.4	-37.3	179.5	-65.5	-178.8	0	0	0	111.7	L36 F43 I44 A91 E94 W318	L36-L40 WeakPolarHBondContact O-CB 3.36Å; L36-L40 VanDerWaalsContact O-CG 3.28Å; L36-L40 WeakPolarHBondContact O-CG 3.35Å; L36-L40 PolarHBondContact O-N 2.78Å; L40-F43 WeakPolarHBondContact O-CB 3.26Å; L40-F43 PolarHBondContact O-N 3.41Å; L40-I44 WeakPolarHBondContact O-CB 3.3Å; L40-I44 WeakPolarHBondContact O-CD1 3.46Å; L40-I44 WeakPolarHBondContact O-CG1 3.37Å; L40-I44 PolarHBondContact O-N 2.85Å; L40-A91 HydrophobicContact CB-CB 4.05Å; L40-A91 HydrophobicContact CD1-CB 3.85Å; L40-E94 HydrophobicContact CD1-CB 4.41Å; L40-E94 HydrophobicContact CD1-CG 4.49Å; L40-W318 HydrophobicContact CD1-CH2 4.06Å; L40-W318 HydrophobicContact CD1-CZ2 3.93Å; L40-W318 HydrophobicContact CD2-CD2 4.21Å; L40-W318 HydrophobicContact CD2-CE3 3.91Å; L40-W318 HydrophobicContact CD2-CH2 3.54Å; L40-W318 HydrophobicContact CD2-CZ2 3.83Å; L40-W318 HydrophobicContact CD2-CZ3 3.58Å; L40-W318 HydrophobicContact CG-CH2 4.33Å
41	G	93.3	Very high	92	Very high	36 Å²	36	59.4 Å²	59.4	37%	0.371	34%	0.336	S	S	.	.	H	α-helix	trans	-63.2	-45.6	175.4	0	0	0	0	0	112.7	G37 M38 I39 F43 I44 L45	G37-G41 PolarHBondContact O-N 3.19Å; M38-G41 PolarHBondContact O-N 2.85Å; I39-G41 PolarHBondContact O-N 3.11Å; G41-F43 VanDerWaalsContact C-N 3.32Å; G41-F43 PolarHBondContact O-N 2.82Å; G41-I44 PolarHBondContact O-N 3.46Å; G41-L45 WeakPolarHBondContact O-CB 3.28Å; G41-L45 PolarHBondContact O-N 2.92Å
42	V	93.4	Very high	92.3	Very high	93 Å²	93	58.5 Å²	58.5	56%	0.564	33%	0.328	S	S	*	.	H	α-helix	trans	-62.7	-42	174.4	171.1	0	0	0	0	110.8	M38 I39 L45 F46	M38-V42 WeakPolarHBondContact O-CG2 3.26Å; M38-V42 PolarHBondContact O-N 3.29Å; I39-V42 PolarHBondContact O-N 3.4Å; V42-L45 PolarHBondContact O-N 3.35Å; V42-F46 VanDerWaalsContact O-CB 3.27Å; V42-F46 WeakPolarHBondContact O-CB 3.25Å; V42-F46 PolarHBondContact O-N 2.82Å
43	F	92.2	Very high	92.6	Very high	30 Å²	30	53.3 Å²	53.3	13%	0.132	31%	0.306	C	S	.	.	H	α-helix	trans	-59.2	-48.8	176.9	176	-110.6	0	0	0	112.2	I39 L40 G41 F46 G47 L87 W318 F322 C325	I39-F43 WeakPolarHBondContact O-CB 3.32Å; I39-F43 PolarHBondContact O-N 2.83Å; L40-F43 WeakPolarHBondContact O-CB 3.26Å; L40-F43 PolarHBondContact O-N 3.41Å; G41-F43 VanDerWaalsContact C-N 3.32Å; G41-F43 PolarHBondContact O-N 2.82Å; F43-F46 PolarHBondContact O-N 3.27Å; F43-G47 PolarHBondContact O-N 2.92Å; F43-L87 HydrophobicContact CD1-CD1 4.24Å; F43-L87 HydrophobicContact CE1-CD1 3.68Å; F43-L87 HydrophobicContact CE1-CD2 4.39Å; F43-L87 HydrophobicContact CZ-CD1 4.4Å; F43-W318 HydrophobicContact CD1-CE3 4.4Å; F43-W318 HydrophobicContact CD1-CZ3 4.02Å; F43-W318 HydrophobicContact CE1-CE3 4.08Å; F43-W318 AromaticContact CE1-CZ3 3.92Å; F43-W318 HydrophobicContact CE1-CZ3 3.92Å; F43-F322 HydrophobicContact CD2-CD2 4.36Å; F43-F322 HydrophobicContact CE2-CB 4.32Å; F43-F322 AromaticContact CE2-CD2 3.71Å; F43-F322 HydrophobicContact CE2-CD2 3.71Å; F43-F322 HydrophobicContact CE2-CG 4.49Å; F43-F322 HydrophobicContact CZ-CB 4.48Å; F43-C325 HydrophobicContact CE2-CB 3.9Å; F43-C325 WeakPolarHBondContact CE2-SG 3.48Å
44	I	94.3	Very high	92.8	Very high	27 Å²	27	51 Å²	51	14%	0.138	29%	0.292	C	S	.	.	H	α-helix	trans	-62.2	-48.2	176.9	-68.7	162.4	0	0	0	111	L40 G41 F46 G47 V48 L87 P88 A91	L40-I44 WeakPolarHBondContact O-CB 3.3Å; L40-I44 WeakPolarHBondContact O-CD1 3.46Å; L40-I44 WeakPolarHBondContact O-CG1 3.37Å; L40-I44 PolarHBondContact O-N 2.85Å; G41-I44 PolarHBondContact O-N 3.46Å; I44-F46 VanDerWaalsContact C-N 3.28Å; I44-F46 PolarHBondContact O-N 3.46Å; I44-G47 PolarHBondContact O-N 2.82Å; I44-V48 HydrophobicContact CG2-CG2 4.33Å; I44-V48 WeakPolarHBondContact O-CG2 3.49Å; I44-V48 PolarHBondContact O-N 3.29Å; I44-L87 HydrophobicContact CD1-CB 4.25Å; I44-L87 HydrophobicContact CG1-CB 3.77Å; I44-L87 HydrophobicContact CG1-CD1 4.37Å; I44-P88 HydrophobicContact CD1-CG 4.45Å; I44-P88 HydrophobicContact CG2-CG 4.24Å; I44-A91 HydrophobicContact CD1-CB 3.92Å
45	L	94.6	Very high	92.9	Very high	113 Å²	113	48.4 Å²	48.4	59%	0.592	28%	0.275	S	S	*	.	H	α-helix	trans	-58.5	-44.2	179.9	-180	65.9	0	0	0	111	G41 V42 V48 V49	G41-L45 WeakPolarHBondContact O-CB 3.28Å; G41-L45 PolarHBondContact O-N 2.92Å; V42-L45 PolarHBondContact O-N 3.35Å; L45-V48 PolarHBondContact O-N 3.49Å; L45-V49 HydrophobicContact CD1-CG2 3.83Å; L45-V49 HydrophobicContact CG-CG2 4.29Å; L45-V49 WeakPolarHBondContact O-CB 3.39Å; L45-V49 VanDerWaalsContact O-CG2 3.29Å; L45-V49 WeakPolarHBondContact O-CG2 3.36Å; L45-V49 PolarHBondContact O-N 3.44Å
46	F	93.6	Very high	92.9	Very high	92 Å²	92	49.7 Å²	49.7	40%	0.404	28%	0.275	S	S	.	.	H	α-helix	trans	-62.7	-45.1	177.6	-175.8	-96.8	0	0	0	112	V42 F43 I44 G50 C325 I329	V42-F46 VanDerWaalsContact O-CB 3.27Å; V42-F46 WeakPolarHBondContact O-CB 3.25Å; V42-F46 PolarHBondContact O-N 2.82Å; F43-F46 PolarHBondContact O-N 3.27Å; I44-F46 VanDerWaalsContact C-N 3.28Å; I44-F46 PolarHBondContact O-N 3.46Å; F46-G50 WeakPolarHBondContact O-CA 3Å; F46-G50 PolarHBondContact O-N 2.94Å; F46-C325 HydrophobicContact CD1-CB 3.84Å; F46-C325 HydrophobicContact CE1-CB 4.05Å; F46-C325 WeakPolarHBondContact CE1-O 3.36Å; F46-I329 HydrophobicContact CE1-CD1 3.78Å; F46-I329 HydrophobicContact CE1-CG1 3.94Å; F46-I329 HydrophobicContact CZ-CD1 3.65Å; F46-I329 HydrophobicContact CZ-CG1 3.57Å
47	G	92.9	Very high	92.9	Very high	0 Å²	0	46.8 Å²	46.8	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-59.9	-47.3	175.8	0	0	0	0	0	112.7	F43 I44 N51 C325	F43-G47 PolarHBondContact O-N 2.92Å; I44-G47 PolarHBondContact O-N 2.82Å; G47-N51 WeakPolarHBondContact O-CB 3.33Å; G47-N51 PolarHBondContact O-N 3.01Å; G47-N51 VanDerWaalsContact O-N 3.08Å; G47-N51 PolarHBondContact O-ND2 3.15Å; G47-C325 VanDerWaalsContact CA-SG 3.6Å
48	V	95.1	Very high	92.7	Very high	35 Å²	35	46.1 Å²	46.1	21%	0.212	25%	0.252	C	S	.	.	H	α-helix	trans	-65.6	-54.4	179.8	172.3	0	0	0	0	111.3	I44 L45 G50 N51 I52 L80	I44-V48 HydrophobicContact CG2-CG2 4.33Å; I44-V48 WeakPolarHBondContact O-CG2 3.49Å; I44-V48 PolarHBondContact O-N 3.29Å; L45-V48 PolarHBondContact O-N 3.49Å; V48-G50 PolarHBondContact O-N 3.4Å; V48-N51 PolarHBondContact O-N 3.38Å; V48-I52 HydrophobicContact CG1-CD1 3.7Å; V48-I52 WeakPolarHBondContact O-CB 3.5Å; V48-I52 WeakPolarHBondContact O-CD1 3.42Å; V48-I52 VanDerWaalsContact O-CG1 3.22Å; V48-I52 WeakPolarHBondContact O-CG1 3.5Å; V48-I52 PolarHBondContact O-N 3.24Å; V48-L80 HydrophobicContact CB-CD1 4.39Å; V48-L80 HydrophobicContact CG1-CD1 4.01Å
49	V	94.3	Very high	92.5	Very high	67 Å²	67	43.9 Å²	43.9	41%	0.406	25%	0.245	S	C	.	.	H	α-helix	trans	-63.6	-43.3	-178	173.9	0	0	0	0	110.8	L45 I52 L53	L45-V49 HydrophobicContact CD1-CG2 3.83Å; L45-V49 HydrophobicContact CG-CG2 4.29Å; L45-V49 WeakPolarHBondContact O-CB 3.39Å; L45-V49 VanDerWaalsContact O-CG2 3.29Å; L45-V49 WeakPolarHBondContact O-CG2 3.36Å; L45-V49 PolarHBondContact O-N 3.44Å; V49-I52 PolarHBondContact O-N 3.4Å; V49-L53 HydrophobicContact CG1-CD1 4.05Å; V49-L53 HydrophobicContact CG1-CG 4.4Å; V49-L53 VanDerWaalsContact O-CG 3.3Å; V49-L53 WeakPolarHBondContact O-CG 3.26Å; V49-L53 PolarHBondContact O-N 3.21Å
50	G	92.9	Very high	92.1	Very high	6 Å²	6	41.7 Å²	41.7	6%	0.062	24%	0.239	C	C	.	.	H	α-helix	trans	-59.3	-49.3	179.2	0	0	0	0	0	112.2	F46 V48 L53 V54 P328	F46-G50 WeakPolarHBondContact O-CA 3Å; F46-G50 PolarHBondContact O-N 2.94Å; V48-G50 PolarHBondContact O-N 3.4Å; G50-L53 WeakPolarHBondContact O-CB 3.22Å; G50-L53 PolarHBondContact O-N 2.94Å; G50-V54 WeakPolarHBondContact O-CG2 3.32Å; G50-V54 PolarHBondContact O-N 3.07Å; G50-P328 VanDerWaalsContact C-CG 3.41Å
51	N	94.7	Very high	91.6	Very high	0 Å²	0	43.5 Å²	43.5	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-69.6	-34.5	-179.7	-74.9	-62.1	0	0	0	112.5	G47 V48 L53 V54 I55 A76 L80 S324	G47-N51 WeakPolarHBondContact O-CB 3.33Å; G47-N51 PolarHBondContact O-N 3.01Å; G47-N51 VanDerWaalsContact O-N 3.08Å; G47-N51 PolarHBondContact O-ND2 3.15Å; V48-N51 PolarHBondContact O-N 3.38Å; N51-L53 PolarHBondContact O-N 3.25Å; N51-V54 PolarHBondContact O-N 2.88Å; N51-I55 WeakPolarHBondContact O-CG1 2.99Å; N51-I55 PolarHBondContact O-N 2.97Å; N51-I55 VanDerWaalsContact O-N 3.09Å; N51-A76 HydrophobicContact CB-CB 4.5Å; N51-L80 HydrophobicContact CB-CB 4.16Å; N51-S324 PolarHBondContact ND2-O 3.45Å
52	I	94.4	Very high	91	Very high	70 Å²	70	50.4 Å²	50.4	36%	0.359	26%	0.261	S	S	.	.	H	α-helix	trans	-60.6	-44.6	170.7	-69.5	166.8	0	0	0	110.9	V48 V49 V54 I55 L56 L80	V48-I52 HydrophobicContact CG1-CD1 3.7Å; V48-I52 WeakPolarHBondContact O-CB 3.5Å; V48-I52 WeakPolarHBondContact O-CD1 3.42Å; V48-I52 VanDerWaalsContact O-CG1 3.22Å; V48-I52 WeakPolarHBondContact O-CG1 3.5Å; V48-I52 PolarHBondContact O-N 3.24Å; V49-I52 PolarHBondContact O-N 3.4Å; I52-V54 VanDerWaalsContact C-N 3.32Å; I52-V54 PolarHBondContact O-N 3.1Å; I52-I55 PolarHBondContact O-N 2.88Å; I52-L56 HydrophobicContact CG2-CD1 3.8Å; I52-L56 HydrophobicContact CG2-CG 4.16Å; I52-L56 WeakPolarHBondContact O-CB 3.41Å; I52-L56 WeakPolarHBondContact O-CG 3.46Å; I52-L56 PolarHBondContact O-N 2.79Å; I52-L80 HydrophobicContact CD1-CD1 4.31Å; I52-L80 HydrophobicContact CG1-CD1 3.92Å; I52-L80 HydrophobicContact CG1-CD2 4.14Å
53	L	91.9	Very high	90.2	Very high	31 Å²	31	52.8 Å²	52.8	16%	0.162	27%	0.266	C	S	.	.	H	α-helix	trans	-61.7	-39.1	177.4	-72.9	172	0	0	0	112	V49 G50 N51 L56 S57 F342 L346	V49-L53 HydrophobicContact CG1-CD1 4.05Å; V49-L53 HydrophobicContact CG1-CG 4.4Å; V49-L53 VanDerWaalsContact O-CG 3.3Å; V49-L53 WeakPolarHBondContact O-CG 3.26Å; V49-L53 PolarHBondContact O-N 3.21Å; G50-L53 WeakPolarHBondContact O-CB 3.22Å; G50-L53 PolarHBondContact O-N 2.94Å; N51-L53 PolarHBondContact O-N 3.25Å; L53-L56 PolarHBondContact O-N 2.86Å; L53-S57 VanDerWaalsContact O-CB 3.29Å; L53-S57 WeakPolarHBondContact O-CB 3.41Å; L53-S57 PolarHBondContact O-N 3.32Å; L53-F342 HydrophobicContact CB-CD1 4.41Å; L53-F342 HydrophobicContact CB-CE1 3.82Å; L53-F342 HydrophobicContact CB-CZ 3.95Å; L53-F342 HydrophobicContact CD1-CE1 4.37Å; L53-L346 HydrophobicContact CD1-CD2 4.46Å
54	V	92.2	Very high	89.4	Confident	0 Å²	0	51.6 Å²	51.6	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-58.7	-49.2	173.6	175.5	0	0	0	0	110.4	G50 N51 I52 S57 V58 I72 A76 P328 Y331 F342	G50-V54 WeakPolarHBondContact O-CG2 3.32Å; G50-V54 PolarHBondContact O-N 3.07Å; N51-V54 PolarHBondContact O-N 2.88Å; I52-V54 VanDerWaalsContact C-N 3.32Å; I52-V54 PolarHBondContact O-N 3.1Å; V54-S57 PolarHBondContact O-N 3.33Å; V54-S57 PolarHBondContact O-OG 3.33Å; V54-V58 PolarHBondContact O-N 3.34Å; V54-I72 HydrophobicContact CG1-CG2 3.93Å; V54-A76 HydrophobicContact CB-CB 4.04Å; V54-A76 HydrophobicContact CG1-CB 3.78Å; V54-P328 HydrophobicContact CG2-CB 4.13Å; V54-P328 HydrophobicContact CG2-CG 4.23Å; V54-Y331 HydrophobicContact CG1-CD2 4.14Å; V54-Y331 HydrophobicContact CG1-CE2 4.23Å; V54-Y331 HydrophobicContact CG2-CD2 3.91Å; V54-Y331 HydrophobicContact CG2-CE2 4.36Å; V54-F342 HydrophobicContact CG2-CE2 4.44Å; V54-F342 HydrophobicContact CG2-CZ 3.77Å
55	I	92.7	Very high	88.8	Confident	34 Å²	34	56.2 Å²	56.2	17%	0.174	28%	0.277	C	S	.	.	H	α-helix	trans	-61.2	-50	179.4	-63.6	166.7	0	0	0	110.7	N51 I52 S57 V58 V59 V73 A76 V77 L80	N51-I55 WeakPolarHBondContact O-CG1 2.99Å; N51-I55 PolarHBondContact O-N 2.97Å; N51-I55 VanDerWaalsContact O-N 3.09Å; I52-I55 PolarHBondContact O-N 2.88Å; I55-S57 VanDerWaalsContact C-N 3.29Å; I55-S57 PolarHBondContact O-N 2.87Å; I55-V58 PolarHBondContact O-N 3.16Å; I55-V59 HydrophobicContact CG2-CG2 4.28Å; I55-V59 WeakPolarHBondContact O-CG2 3.43Å; I55-V59 PolarHBondContact O-N 3.31Å; I55-V73 HydrophobicContact CG1-CG1 4.45Å; I55-A76 HydrophobicContact CD1-CB 4.36Å; I55-A76 HydrophobicContact CG1-CB 3.85Å; I55-V77 HydrophobicContact CD1-CG2 3.93Å; I55-L80 HydrophobicContact CD1-CD2 3.99Å
56	L	90.6	Very high	88.3	Confident	72 Å²	72	54 Å²	54	38%	0.377	27%	0.268	S	S	.	.	H	α-helix	trans	-60.7	-37.7	179.4	-70.5	177.4	0	0	0	112.2	I52 L53 V58 V59 C60 L345	I52-L56 HydrophobicContact CG2-CD1 3.8Å; I52-L56 HydrophobicContact CG2-CG 4.16Å; I52-L56 WeakPolarHBondContact O-CB 3.41Å; I52-L56 WeakPolarHBondContact O-CG 3.46Å; I52-L56 PolarHBondContact O-N 2.79Å; L53-L56 PolarHBondContact O-N 2.86Å; L56-V58 VanDerWaalsContact C-N 3.29Å; L56-V58 PolarHBondContact O-N 3.33Å; L56-V59 PolarHBondContact O-N 3.29Å; L56-C60 VanDerWaalsContact O-CB 3.25Å; L56-C60 WeakPolarHBondContact O-CB 3.46Å; L56-C60 PolarHBondContact O-N 3.45Å; L56-C60 PolarHBondContact O-SG 2.88Å; L56-C60 VanDerWaalsContact O-SG 3.33Å; L56-L345 HydrophobicContact CB-CD1 3.9Å
57	S	88.9	Confident	87.9	Confident	0 Å²	0	50.6 Å²	50.6	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-58.6	-41.1	-179.4	74.9	0	0	0	0	112.3	L53 V54 I55 H61 F338	L53-S57 VanDerWaalsContact O-CB 3.29Å; L53-S57 WeakPolarHBondContact O-CB 3.41Å; L53-S57 PolarHBondContact O-N 3.32Å; V54-S57 PolarHBondContact O-N 3.33Å; V54-S57 PolarHBondContact O-OG 3.33Å; I55-S57 VanDerWaalsContact C-N 3.29Å; I55-S57 PolarHBondContact O-N 2.87Å; S57-H61 WeakPolarHBondContact O-CB 3.32Å; S57-H61 PolarHBondContact O-N 3.13Å; S57-H61 PolarHBondContact O-ND1 3.35Å; S57-H61 VanDerWaalsContact O-ND1 3.13Å; S57-F338 WeakPolarHBondContact OG-CD1 3.36Å; S57-F338 WeakPolarHBondContact OG-CE1 3.3Å
58	V	88.6	Confident	87.5	Confident	8 Å²	8	51.4 Å²	51.4	5%	0.048	26%	0.26	C	S	.	.	H	α-helix	trans	-78.9	-39.1	179.3	-179.5	0	0	0	0	111.6	V54 I55 L56 H69 V73 F338	V54-V58 PolarHBondContact O-N 3.34Å; I55-V58 PolarHBondContact O-N 3.16Å; L56-V58 VanDerWaalsContact C-N 3.29Å; L56-V58 PolarHBondContact O-N 3.33Å; V58-H69 HydrophobicContact CG1-CB 4.03Å; V58-H69 HydrophobicContact CG2-CB 4.31Å; V58-V73 HydrophobicContact CB-CG2 3.7Å; V58-V73 HydrophobicContact CG1-CG2 3.82Å; V58-V73 HydrophobicContact CG2-CG2 3.82Å; V58-F338 HydrophobicContact CG2-CE1 3.83Å; V58-F338 HydrophobicContact CG2-CZ 4.06Å
59	V	86.9	Confident	87.2	Confident	79 Å²	79	50.8 Å²	50.8	48%	0.479	25%	0.254	S	S	.	.	H	α-helix	trans	-67.8	-43.9	179.9	173.8	0	0	0	0	111.1	I55 L56 R65	I55-V59 HydrophobicContact CG2-CG2 4.28Å; I55-V59 WeakPolarHBondContact O-CG2 3.43Å; I55-V59 PolarHBondContact O-N 3.31Å; L56-V59 PolarHBondContact O-N 3.29Å; V59-R65 PolarHBondContact O-NH2 3.31Å
60	C	84.4	Confident	87	Confident	67 Å²	67	52.5 Å²	52.5	45%	0.453	25%	0.254	S	S	.	.	H	α-helix	trans	-75.8	-31.2	-177.1	-64.8	0	0	0	0	113.1	L56 L345	L56-C60 VanDerWaalsContact O-CB 3.25Å; L56-C60 WeakPolarHBondContact O-CB 3.46Å; L56-C60 PolarHBondContact O-N 3.45Å; L56-C60 PolarHBondContact O-SG 2.88Å; L56-C60 VanDerWaalsContact O-SG 3.33Å; C60-L345 HydrophobicContact CB-CD2 4.26Å
61	H	82.7	Confident	86.9	Confident	54 Å²	54	52.4 Å²	52.4	25%	0.25	25%	0.252	C	S	.	.			trans	-103.7	110.3	-175.7	-64.9	83.1	0	0	0	112.5	S57 H63 L64	S57-H61 WeakPolarHBondContact O-CB 3.32Å; S57-H61 PolarHBondContact O-N 3.13Å; S57-H61 PolarHBondContact O-ND1 3.35Å; S57-H61 VanDerWaalsContact O-ND1 3.13Å; H61-H63 PolarHBondContact O-N 3.3Å; H61-L64 HydrophobicContact CB-CD1 4.12Å; H61-L64 HydrophobicContact CB-CG 4.29Å; H61-L64 PolarHBondContact O-N 3.17Å; H61-L64 VanDerWaalsContact O-N 3.11Å
62	R	79.2	Confident	86.8	Confident	180 Å²	180	53.2 Å²	53.2	68%	0.679	26%	0.256	S	S	*	.	G	3₁₀ helix	trans	-60.3	-29.9	-179.1	-167.2	175.7	-177.2	179.9	0.5	113.8	L64 R65	R62-L64 VanDerWaalsContact C-N 3.26Å; R62-L64 PolarHBondContact O-N 3.07Å; R62-R65 PolarHBondContact O-N 2.95Å
63	H	76.4	Confident	86.7	Confident	144 Å²	144	51.2 Å²	51.2	67%	0.667	25%	0.247	S	C	*	.	G	3₁₀ helix	trans	-66.2	-27.1	178.8	-177	-110.5	0	0	0	112.9	H61 R65 E337	H61-H63 PolarHBondContact O-N 3.3Å; H63-R65 VanDerWaalsContact C-N 3.33Å; H63-E337 IonicContact CE1-OE2 2.85Å; H63-E337 PolarHBondContact CE1-OE2 3.48Å; H63-E337 IonicContact ND1-OE2 3.27Å; H63-E337 PolarHBondContact ND1-OE2 3.39Å
64	L	76.8	Confident	86.8	Confident	5 Å²	5	50.5 Å²	50.5	3%	0.026	24%	0.244	C	C	.	.	G	3₁₀ helix	trans	-86.9	3.1	179.1	-65	176.7	0	0	0	113	H61 R62 T66 H69 E337 F338 A341	H61-L64 HydrophobicContact CB-CD1 4.12Å; H61-L64 HydrophobicContact CB-CG 4.29Å; H61-L64 PolarHBondContact O-N 3.17Å; H61-L64 VanDerWaalsContact O-N 3.11Å; R62-L64 VanDerWaalsContact C-N 3.26Å; R62-L64 PolarHBondContact O-N 3.07Å; L64-T66 PolarHBondContact O-N 3.49Å; L64-H69 WeakPolarHBondContact O-CB 3.36Å; L64-H69 PolarHBondContact O-ND1 2.92Å; L64-E337 HydrophobicContact CD2-CB 3.84Å; L64-F338 HydrophobicContact CD1-CD1 4.45Å; L64-A341 HydrophobicContact CD1-CB 3.9Å
65	R	81.2	Confident	86.8	Confident	124 Å²	124	50.5 Å²	50.5	47%	0.468	24%	0.244	S	C	.	.			trans	-84.5	54.6	-176.7	-62.2	-176	-175.2	177.6	-0.1	113.1	V59 R62 H63	V59-R65 PolarHBondContact O-NH2 3.31Å; R62-R65 PolarHBondContact O-N 2.95Å; H63-R65 VanDerWaalsContact C-N 3.33Å
66	T	84.3	Confident	86.9	Confident	65 Å²	65	48.9 Å²	48.9	40%	0.399	24%	0.235	S	C	.	.	S	Bend	trans	-97.7	165.1	173.4	76.1	0	0	0	0	111.4	L64 T68 H69 Y70	L64-T66 PolarHBondContact O-N 3.49Å; T66-T68 VanDerWaalsContact C-N 3.32Å; T66-T68 PolarHBondContact O-N 2.9Å; T66-H69 PolarHBondContact O-N 3.07Å; T66-H69 VanDerWaalsContact O-N 3.11Å; T66-H69 PolarHBondContact OG1-ND1 3.31Å; T66-Y70 WeakPolarHBondContact O-CD2 3.42Å; T66-Y70 PolarHBondContact O-N 3.35Å
67	V	84.6	Confident	87.1	Confident	21 Å²	21	48.4 Å²	48.4	13%	0.127	24%	0.235	C	C	.	.	H	α-helix	trans	-55.1	-45.5	-178.4	179.5	0	0	0	0	111.9	H69 Y70 F71 M145 A150	V67-H69 VanDerWaalsContact C-N 3.3Å; V67-H69 PolarHBondContact O-N 3.35Å; V67-Y70 WeakPolarHBondContact O-CB 3.29Å; V67-Y70 PolarHBondContact O-N 2.73Å; V67-F71 HydrophobicContact CG1-CE2 4.08Å; V67-M145 HydrophobicContact CG1-CB 4.47Å; V67-A150 HydrophobicContact CG1-CB 3.55Å
68	T	85.6	Confident	87.5	Confident	17 Å²	17	48.4 Å²	48.4	10%	0.104	24%	0.235	C	C	.	.	H	α-helix	trans	-57.3	-39.4	176.8	-48.5	0	0	0	0	113.5	T66 Y70 F71 I72 D130 R131 Y141	T66-T68 VanDerWaalsContact C-N 3.32Å; T66-T68 PolarHBondContact O-N 2.9Å; T68-Y70 VanDerWaalsContact C-N 3.28Å; T68-Y70 PolarHBondContact O-N 3.07Å; T68-F71 PolarHBondContact O-N 3.35Å; T68-I72 PolarHBondContact O-N 3.39Å; T68-D130 WeakPolarHBondContact CG2-OD2 3.34Å; T68-D130 PolarHBondContact OG1-OD2 3.36Å; T68-R131 PolarHBondContact OG1-NH2 3.42Å; T68-Y141 PolarHBondContact OG1-OH 2.92Å; T68-Y141 VanDerWaalsContact OG1-OH 3.11Å
69	H	87.6	Confident	87.8	Confident	22 Å²	22	48.1 Å²	48.1	10%	0.102	23%	0.233	C	C	.	.	H	α-helix	trans	-70.9	-24.5	179.9	-64.8	106.6	0	0	0	112.2	V58 L64 T66 V67 F71 I72 V73 F338	V58-H69 HydrophobicContact CG1-CB 4.03Å; V58-H69 HydrophobicContact CG2-CB 4.31Å; L64-H69 WeakPolarHBondContact O-CB 3.36Å; L64-H69 PolarHBondContact O-ND1 2.92Å; T66-H69 PolarHBondContact O-N 3.07Å; T66-H69 VanDerWaalsContact O-N 3.11Å; T66-H69 PolarHBondContact OG1-ND1 3.31Å; V67-H69 VanDerWaalsContact C-N 3.3Å; V67-H69 PolarHBondContact O-N 3.35Å; H69-F71 VanDerWaalsContact C-N 3.34Å; H69-I72 PolarHBondContact O-N 2.93Å; H69-V73 WeakPolarHBondContact O-CG2 3.44Å; H69-V73 PolarHBondContact O-N 3.11Å; H69-F338 AromaticContact CD2-CE2 3.44Å; H69-F338 VanDerWaalsContact CD2-CE2 3.44Å; H69-F338 WeakPolarHBondContact CD2-CE2 3.42Å; H69-F338 AromaticContact CD2-CZ 3.44Å; H69-F338 VanDerWaalsContact CD2-CZ 3.44Å; H69-F338 WeakPolarHBondContact CD2-CZ 3.28Å; H69-F338 AromaticContact NE2-CE2 3.56Å
70	Y	89.8	Confident	88.2	Confident	104 Å²	104	46.1 Å²	46.1	41%	0.408	22%	0.22	S	C	.	.	H	α-helix	trans	-65.3	-37	170.4	-71.5	-81	0	0	0	112	T66 V67 T68 V73 N74	T66-Y70 WeakPolarHBondContact O-CD2 3.42Å; T66-Y70 PolarHBondContact O-N 3.35Å; V67-Y70 WeakPolarHBondContact O-CB 3.29Å; V67-Y70 PolarHBondContact O-N 2.73Å; T68-Y70 VanDerWaalsContact C-N 3.28Å; T68-Y70 PolarHBondContact O-N 3.07Å; Y70-V73 PolarHBondContact O-N 3.15Å; Y70-N74 PolarHBondContact O-N 2.91Å
71	F	92	Very high	88.7	Confident	4 Å²	4	45.7 Å²	45.7	2%	0.018	21%	0.213	C	C	.	.	H	α-helix	trans	-67.6	-37.5	174.4	-61.6	-52.9	0	0	0	112.2	V67 T68 H69 V73 N74 L75 V126 I127 D130 A150 A153 V154	V67-F71 HydrophobicContact CG1-CE2 4.08Å; T68-F71 PolarHBondContact O-N 3.35Å; H69-F71 VanDerWaalsContact C-N 3.34Å; F71-V73 VanDerWaalsContact C-N 3.34Å; F71-N74 PolarHBondContact O-N 2.64Å; F71-L75 PolarHBondContact O-N 2.79Å; F71-V126 HydrophobicContact CD1-CG1 3.73Å; F71-V126 HydrophobicContact CD2-CG1 4.4Å; F71-V126 HydrophobicContact CE1-CG1 3.45Å; F71-V126 VanDerWaalsContact CE1-CG1 3.45Å; F71-V126 HydrophobicContact CE2-CG1 4.16Å; F71-V126 HydrophobicContact CG-CG1 4.21Å; F71-V126 HydrophobicContact CZ-CG1 3.68Å; F71-I127 HydrophobicContact CB-CD1 4.29Å; F71-I127 HydrophobicContact CB-CG1 3.62Å; F71-D130 HydrophobicContact CD2-CB 4.15Å; F71-D130 HydrophobicContact CE2-CB 3.94Å; F71-A150 HydrophobicContact CE1-CB 4.03Å; F71-A150 HydrophobicContact CE2-CB 4.4Å; F71-A150 HydrophobicContact CZ-CB 3.64Å; F71-A153 HydrophobicContact CE1-CB 4.44Å; F71-V154 HydrophobicContact CD1-CG2 3.93Å; F71-V154 HydrophobicContact CE1-CG2 3.97Å
72	I	91.2	Very high	89.3	Confident	16 Å²	16	43.3 Å²	43.3	8%	0.082	20%	0.202	C	C	.	.	H	α-helix	trans	-63.6	-41.1	173.6	-63.6	171.2	0	0	0	110.8	V54 T68 H69 L75 A76 Y331 F338	V54-I72 HydrophobicContact CG1-CG2 3.93Å; T68-I72 PolarHBondContact O-N 3.39Å; H69-I72 PolarHBondContact O-N 2.93Å; I72-L75 PolarHBondContact O-N 2.86Å; I72-A76 PolarHBondContact O-N 3.47Å; I72-Y331 HydrophobicContact CG2-CD2 4.11Å; I72-Y331 HydrophobicContact CG2-CE1 4.22Å; I72-Y331 HydrophobicContact CG2-CE2 3.67Å; I72-F338 HydrophobicContact CD1-CE2 4.06Å; I72-F338 HydrophobicContact CD1-CZ 4.14Å; I72-F338 HydrophobicContact CG2-CZ 4.15Å
73	V	92.3	Very high	90.1	Very high	28 Å²	28	34.7 Å²	34.7	17%	0.17	17%	0.17	C	C	.	.	H	α-helix	trans	-64	-42.2	174	170.4	0	0	0	0	111.1	I55 V58 H69 Y70 F71 L75 A76 V77	I55-V73 HydrophobicContact CG1-CG1 4.45Å; V58-V73 HydrophobicContact CB-CG2 3.7Å; V58-V73 HydrophobicContact CG1-CG2 3.82Å; V58-V73 HydrophobicContact CG2-CG2 3.82Å; H69-V73 WeakPolarHBondContact O-CG2 3.44Å; H69-V73 PolarHBondContact O-N 3.11Å; Y70-V73 PolarHBondContact O-N 3.15Å; F71-V73 VanDerWaalsContact C-N 3.34Å; V73-L75 VanDerWaalsContact C-N 3.31Å; V73-L75 PolarHBondContact O-N 3.21Å; V73-A76 PolarHBondContact O-N 3.32Å; V73-V77 HydrophobicContact CG1-CG2 4.41Å; V73-V77 WeakPolarHBondContact O-CG2 3.31Å; V73-V77 PolarHBondContact O-N 3.23Å
74	N	94.3	Very high	90.9	Very high	16 Å²	16	30.5 Å²	30.5	9%	0.086	16%	0.156	C	C	.	.	H	α-helix	trans	-59.5	-43.1	175.9	-174.2	74.8	0	0	0	112	Y70 F71 V77 A78 S123 V154 W158	Y70-N74 PolarHBondContact O-N 2.91Å; F71-N74 PolarHBondContact O-N 2.64Å; N74-V77 PolarHBondContact O-N 2.83Å; N74-A78 PolarHBondContact O-N 3.11Å; N74-S123 PolarHBondContact ND2-OG 2.88Å; N74-V154 HydrophobicContact CB-CG2 4.4Å; N74-V154 WeakPolarHBondContact OD1-CG1 3.48Å; N74-W158 PolarHBondContact OD1-NE1 3.26Å
75	L	93.3	Very high	91.7	Very high	0 Å²	0	32.6 Å²	32.6	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-61	-46.5	174.7	179.3	57	0	0	0	111.3	F71 I72 V73 V77 A78 D79 L124 I127 Y331	F71-L75 PolarHBondContact O-N 2.79Å; I72-L75 PolarHBondContact O-N 2.86Å; V73-L75 VanDerWaalsContact C-N 3.31Å; V73-L75 PolarHBondContact O-N 3.21Å; L75-V77 VanDerWaalsContact C-N 3.27Å; L75-V77 PolarHBondContact O-N 3.22Å; L75-A78 PolarHBondContact O-N 3.21Å; L75-A78 VanDerWaalsContact O-N 3.16Å; L75-D79 PolarHBondContact O-N 2.99Å; L75-L124 HydrophobicContact CD1-CG 4.47Å; L75-L124 HydrophobicContact CD2-CD2 3.63Å; L75-L124 HydrophobicContact CD2-CG 4.16Å; L75-I127 HydrophobicContact CB-CD1 4.45Å; L75-I127 HydrophobicContact CD2-CD1 3.91Å; L75-Y331 WeakPolarHBondContact CD2-OH 3.37Å
76	A	94.8	Very high	92.3	Very high	0 Å²	0	26.7 Å²	26.7	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-62.5	-31.5	176	0	0	0	0	0	113.2	N51 V54 I55 I72 V73 L80	N51-A76 HydrophobicContact CB-CB 4.5Å; V54-A76 HydrophobicContact CB-CB 4.04Å; V54-A76 HydrophobicContact CG1-CB 3.78Å; I55-A76 HydrophobicContact CD1-CB 4.36Å; I55-A76 HydrophobicContact CG1-CB 3.85Å; I72-A76 PolarHBondContact O-N 3.47Å; V73-A76 PolarHBondContact O-N 3.32Å; A76-L80 WeakPolarHBondContact O-CB 3.47Å; A76-L80 PolarHBondContact O-N 3.29Å
77	V	95.4	Very high	92.7	Very high	62 Å²	62	23.6 Å²	23.6	38%	0.376	13%	0.128	S	C	.	.	H	α-helix	trans	-68.9	-43.1	173.8	168.7	0	0	0	0	111.1	I55 V73 N74 L75 L80 L81 W158	I55-V77 HydrophobicContact CD1-CG2 3.93Å; V73-V77 HydrophobicContact CG1-CG2 4.41Å; V73-V77 WeakPolarHBondContact O-CG2 3.31Å; V73-V77 PolarHBondContact O-N 3.23Å; N74-V77 PolarHBondContact O-N 2.83Å; L75-V77 VanDerWaalsContact C-N 3.27Å; L75-V77 PolarHBondContact O-N 3.22Å; V77-L80 PolarHBondContact O-N 3.4Å; V77-L81 WeakPolarHBondContact O-CB 3.29Å; V77-L81 PolarHBondContact O-N 3.45Å; V77-W158 HydrophobicContact CG1-CZ2 4.5Å
78	A	95.7	Very high	93.1	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-64.2	-44.6	176.4	0	0	0	0	0	111.7	N74 L75 L80 L81 L82 A119 S120 W158	N74-A78 PolarHBondContact O-N 3.11Å; L75-A78 PolarHBondContact O-N 3.21Å; L75-A78 VanDerWaalsContact O-N 3.16Å; A78-L80 VanDerWaalsContact C-N 3.35Å; A78-L80 PolarHBondContact O-N 2.88Å; A78-L81 PolarHBondContact O-N 3.07Å; A78-L82 PolarHBondContact O-N 2.75Å; A78-A119 HydrophobicContact CB-CB 4.17Å; A78-S120 WeakPolarHBondContact CB-OG 3.42Å; A78-W158 HydrophobicContact CB-CH2 4.36Å; A78-W158 HydrophobicContact CB-CZ2 4.45Å
79	D	95.3	Very high	93.5	Very high	2 Å²	2	26.5 Å²	26.5	1%	0.011	14%	0.142	C	C	.	.	H	α-helix	trans	-66.3	-35.2	176.2	-74.1	-34.4	0	0	0	112.4	L75 S83 S324 N327	L75-D79 PolarHBondContact O-N 2.99Å; D79-S83 VanDerWaalsContact O-CB 3.28Å; D79-S83 WeakPolarHBondContact O-CB 3.22Å; D79-S83 PolarHBondContact O-N 3.45Å; D79-S83 PolarHBondContact O-OG 2.91Å; D79-S324 WeakPolarHBondContact OD1-CB 3.27Å; D79-N327 PolarHBondContact OD2-ND2 3.49Å
80	L	95.6	Very high	93.7	Very high	38 Å²	38	25.8 Å²	25.8	20%	0.199	14%	0.139	C	C	.	.	H	α-helix	trans	-67.2	-41.1	174.4	-179.3	63.1	0	0	0	111.3	V48 N51 I52 I55 A76 V77 A78 S83 S84	V48-L80 HydrophobicContact CB-CD1 4.39Å; V48-L80 HydrophobicContact CG1-CD1 4.01Å; N51-L80 HydrophobicContact CB-CB 4.16Å; I52-L80 HydrophobicContact CD1-CD1 4.31Å; I52-L80 HydrophobicContact CG1-CD1 3.92Å; I52-L80 HydrophobicContact CG1-CD2 4.14Å; I55-L80 HydrophobicContact CD1-CD2 3.99Å; A76-L80 WeakPolarHBondContact O-CB 3.47Å; A76-L80 PolarHBondContact O-N 3.29Å; V77-L80 PolarHBondContact O-N 3.4Å; A78-L80 VanDerWaalsContact C-N 3.35Å; A78-L80 PolarHBondContact O-N 2.88Å; L80-S83 PolarHBondContact O-N 2.79Å; L80-S84 VanDerWaalsContact O-CB 3.29Å; L80-S84 WeakPolarHBondContact O-CB 3.49Å; L80-S84 PolarHBondContact O-N 3.04Å; L80-S84 PolarHBondContact O-OG 3.05Å
81	L	95.4	Very high	93.8	Very high	58 Å²	58	21.1 Å²	21.1	30%	0.304	12%	0.122	S	C	.	.	H	α-helix	trans	-60.8	-51	174.6	-172.8	63.4	0	0	0	109.8	V77 A78 S83 S84 T85 C116 W158	V77-L81 WeakPolarHBondContact O-CB 3.29Å; V77-L81 PolarHBondContact O-N 3.45Å; A78-L81 PolarHBondContact O-N 3.07Å; L81-S83 VanDerWaalsContact C-N 3.34Å; L81-S83 PolarHBondContact O-N 3.35Å; L81-S84 PolarHBondContact O-N 3.47Å; L81-S84 PolarHBondContact O-OG 2.86Å; L81-T85 HydrophobicContact CD1-CG2 3.78Å; L81-T85 PolarHBondContact O-N 2.99Å; L81-T85 PolarHBondContact O-OG1 2.79Å; L81-C116 WeakPolarHBondContact CD2-SG 3.44Å; L81-C116 VanDerWaalsContact CG-SG 3.52Å; L81-W158 HydrophobicContact CD2-CH2 4.46Å
82	L	95	Very high	93.8	Very high	3 Å²	3	23.4 Å²	23.4	2%	0.016	14%	0.136	C	C	.	.	I	π-helix	trans	-52.9	-50.4	174.2	-175.3	70.4	0	0	0	111.9	A78 S84 V86 L87 C116 Y321	A78-L82 PolarHBondContact O-N 2.75Å; L82-S84 VanDerWaalsContact C-N 3.32Å; L82-S84 PolarHBondContact O-N 3.19Å; L82-V86 HydrophobicContact CD1-CB 3.84Å; L82-V86 HydrophobicContact CD1-CG1 4.03Å; L82-V86 HydrophobicContact CD1-CG2 3.98Å; L82-V86 WeakPolarHBondContact O-CA 3.49Å; L82-V86 WeakPolarHBondContact O-CB 3.23Å; L82-V86 PolarHBondContact O-N 2.9Å; L82-L87 PolarHBondContact O-N 3.41Å; L82-C116 HydrophobicContact CB-CB 3.91Å; L82-C116 HydrophobicContact CD1-CB 3.97Å; L82-Y321 HydrophobicContact CD1-CD1 4.3Å; L82-Y321 HydrophobicContact CD1-CE1 3.88Å; L82-Y321 HydrophobicContact CD2-CD1 4.07Å; L82-Y321 HydrophobicContact CD2-CE1 4.45Å
83	S	94.8	Very high	93.7	Very high	0 Å²	0	24.9 Å²	24.9	0%	0	14%	0.142	C	C	.	.	I	π-helix	trans	-67.7	-30	-174.9	-57	0	0	0	0	113.7	D79 L80 L81 P88	D79-S83 VanDerWaalsContact O-CB 3.28Å; D79-S83 WeakPolarHBondContact O-CB 3.22Å; D79-S83 PolarHBondContact O-N 3.45Å; D79-S83 PolarHBondContact O-OG 2.91Å; L80-S83 PolarHBondContact O-N 2.79Å; L81-S83 VanDerWaalsContact C-N 3.34Å; L81-S83 PolarHBondContact O-N 3.35Å; S83-P88 WeakPolarHBondContact O-CD 3.44Å
84	S	93.8	Very high	93.5	Very high	55 Å²	55	25.6 Å²	25.6	39%	0.385	14%	0.144	S	C	.	.	I	π-helix	trans	-96	-32.1	-176.2	59.2	0	0	0	0	113.7	L80 L81 L82 P88	L80-S84 VanDerWaalsContact O-CB 3.29Å; L80-S84 WeakPolarHBondContact O-CB 3.49Å; L80-S84 PolarHBondContact O-N 3.04Å; L80-S84 PolarHBondContact O-OG 3.05Å; L81-S84 PolarHBondContact O-N 3.47Å; L81-S84 PolarHBondContact O-OG 2.86Å; L82-S84 VanDerWaalsContact C-N 3.32Å; L82-S84 PolarHBondContact O-N 3.19Å; S84-P88 WeakPolarHBondContact O-CG 3.29Å
85	T	92.9	Very high	93.2	Very high	49 Å²	49	27.6 Å²	27.6	30%	0.301	15%	0.154	S	C	.	.	I	π-helix	trans	-111.5	-17.6	-173.9	67.5	0	0	0	0	114.4	L81 F89	L81-T85 HydrophobicContact CD1-CG2 3.78Å; L81-T85 PolarHBondContact O-N 2.99Å; L81-T85 PolarHBondContact O-OG1 2.79Å; T85-F89 WeakPolarHBondContact O-CD2 3.38Å; T85-F89 WeakPolarHBondContact O-CE2 3.44Å
86	V	94.1	Very high	92.9	Very high	0 Å²	0	31.2 Å²	31.2	0%	0	17%	0.173	C	C	.	.	I	π-helix	trans	-108.4	-56.1	-178.9	-178.3	0	0	0	0	110.2	L82 P88 F89 S90 W109 V112 D113 Y321	L82-V86 HydrophobicContact CD1-CB 3.84Å; L82-V86 HydrophobicContact CD1-CG1 4.03Å; L82-V86 HydrophobicContact CD1-CG2 3.98Å; L82-V86 WeakPolarHBondContact O-CA 3.49Å; L82-V86 WeakPolarHBondContact O-CB 3.23Å; L82-V86 PolarHBondContact O-N 2.9Å; V86-P88 VanDerWaalsContact C-CD 3.48Å; V86-F89 PolarHBondContact O-N 2.89Å; V86-S90 PolarHBondContact O-N 3.42Å; V86-S90 PolarHBondContact O-OG 3.25Å; V86-W109 PolarHBondContact O-NE1 2.98Å; V86-V112 HydrophobicContact CG2-CB 4.48Å; V86-V112 HydrophobicContact CG2-CG1 3.78Å; V86-D113 HydrophobicContact CG1-CB 3.88Å; V86-D113 WeakPolarHBondContact CG1-OD1 3.43Å; V86-D113 HydrophobicContact CG2-CB 4.42Å; V86-Y321 VanDerWaalsContact CG1-OH 3.31Å; V86-Y321 WeakPolarHBondContact CG1-OH 3.32Å
87	L	93.3	Very high	92.4	Very high	0 Å²	0	37 Å²	37	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-57.1	-39.9	-174	-60.9	-173.7	0	0	0	115.1	F43 I44 L82 F89 S90 A91 W318 Y321	F43-L87 HydrophobicContact CD1-CD1 4.24Å; F43-L87 HydrophobicContact CE1-CD1 3.68Å; F43-L87 HydrophobicContact CE1-CD2 4.39Å; F43-L87 HydrophobicContact CZ-CD1 4.4Å; I44-L87 HydrophobicContact CD1-CB 4.25Å; I44-L87 HydrophobicContact CG1-CB 3.77Å; I44-L87 HydrophobicContact CG1-CD1 4.37Å; L82-L87 PolarHBondContact O-N 3.41Å; L87-F89 VanDerWaalsContact C-N 3.32Å; L87-F89 PolarHBondContact O-N 3.42Å; L87-S90 PolarHBondContact O-N 3.34Å; L87-A91 WeakPolarHBondContact O-CB 3.35Å; L87-A91 PolarHBondContact O-N 2.93Å; L87-W318 HydrophobicContact CD2-CZ3 4.31Å; L87-Y321 HydrophobicContact CD2-CD1 3.95Å; L87-Y321 HydrophobicContact CD2-CD2 3.23Å; L87-Y321 HydrophobicContact CD2-CE1 4.29Å; L87-Y321 HydrophobicContact CD2-CE2 3.6Å; L87-Y321 HydrophobicContact CD2-CG 3.39Å
88	P	93.9	Very high	91.9	Very high	40 Å²	40	41.2 Å²	41.2	26%	0.26	21%	0.213	S	C	.	.	H	α-helix	trans	-63.8	-39.4	179.8	-24.2	36.7	0	0	0	112.4	I44 S83 S84 V86 A91 V92	I44-P88 HydrophobicContact CD1-CG 4.45Å; I44-P88 HydrophobicContact CG2-CG 4.24Å; S83-P88 WeakPolarHBondContact O-CD 3.44Å; S84-P88 WeakPolarHBondContact O-CG 3.29Å; V86-P88 VanDerWaalsContact C-CD 3.48Å; P88-A91 PolarHBondContact O-N 2.84Å; P88-V92 WeakPolarHBondContact O-CG2 3.49Å; P88-V92 PolarHBondContact O-N 3.5Å
89	F	93.2	Very high	91.6	Very high	60 Å²	60	41.7 Å²	41.7	26%	0.263	22%	0.215	S	C	.	.	H	α-helix	trans	-74.5	-37.5	178.7	-60.3	-82.3	0	0	0	111.3	T85 V86 L87 A91 V92 F93 F101 F105	T85-F89 WeakPolarHBondContact O-CD2 3.38Å; T85-F89 WeakPolarHBondContact O-CE2 3.44Å; V86-F89 PolarHBondContact O-N 2.89Å; L87-F89 VanDerWaalsContact C-N 3.32Å; L87-F89 PolarHBondContact O-N 3.42Å; F89-A91 VanDerWaalsContact C-N 3.3Å; F89-A91 PolarHBondContact O-N 3.37Å; F89-V92 PolarHBondContact O-N 3.18Å; F89-F93 WeakPolarHBondContact O-CB 3.36Å; F89-F93 PolarHBondContact O-N 3.03Å; F89-F101 HydrophobicContact CD1-CD1 4.39Å; F89-F101 HydrophobicContact CD1-CD2 4.2Å; F89-F101 HydrophobicContact CD1-CE1 4Å; F89-F101 AromaticContact CD1-CE2 3.8Å; F89-F101 HydrophobicContact CD1-CE2 3.8Å; F89-F101 HydrophobicContact CD1-CG 4.49Å; F89-F101 AromaticContact CD1-CZ 3.69Å; F89-F101 HydrophobicContact CD1-CZ 3.69Å; F89-F101 HydrophobicContact CE1-CD1 4.43Å; F89-F101 HydrophobicContact CE1-CE1 4.05Å; F89-F101 HydrophobicContact CE1-CZ 4.16Å; F89-F105 HydrophobicContact CB-CE1 4.36Å; F89-F105 AromaticContact CD1-CE1 3.43Å; F89-F105 HydrophobicContact CD1-CE1 3.43Å; F89-F105 VanDerWaalsContact CD1-CE1 3.43Å; F89-F105 AromaticContact CD1-CZ 3.76Å; F89-F105 HydrophobicContact CD1-CZ 3.76Å; F89-F105 HydrophobicContact CD2-CE1 4.31Å; F89-F105 HydrophobicContact CD2-CZ 4.14Å; F89-F105 AromaticContact CE1-CE1 3.66Å; F89-F105 HydrophobicContact CE1-CE1 3.66Å; F89-F105 AromaticContact CE1-CZ 3.54Å; F89-F105 HydrophobicContact CE1-CZ 3.54Å; F89-F105 HydrophobicContact CE2-CE1 4.49Å; F89-F105 AromaticContact CE2-CZ 3.93Å; F89-F105 HydrophobicContact CE2-CZ 3.93Å; F89-F105 AromaticContact CG-CE1 3.77Å; F89-F105 HydrophobicContact CG-CE1 3.77Å; F89-F105 HydrophobicContact CG-CZ 4.04Å; F89-F105 HydrophobicContact CZ-CE1 4.19Å; F89-F105 AromaticContact CZ-CZ 3.63Å; F89-F105 HydrophobicContact CZ-CZ 3.63Å
90	S	91.6	Very high	91.2	Very high	6 Å²	6	45.3 Å²	45.3	4%	0.042	24%	0.237	C	C	.	.	H	α-helix	trans	-60.9	-39.3	171	-52.5	0	0	0	0	111.7	V86 L87 F93 E94 W109	V86-S90 PolarHBondContact O-N 3.42Å; V86-S90 PolarHBondContact O-OG 3.25Å; L87-S90 PolarHBondContact O-N 3.34Å; S90-F93 PolarHBondContact O-N 3.41Å; S90-E94 WeakPolarHBondContact O-CB 3.45Å; S90-E94 PolarHBondContact O-N 3.42Å; S90-W109 VanDerWaalsContact OG-CZ2 3.32Å; S90-W109 WeakPolarHBondContact OG-CZ2 3.44Å; S90-W109 PolarHBondContact OG-NE1 3.22Å
91	A	92	Very high	90.9	Very high	7 Å²	7	47.2 Å²	47.2	6%	0.058	24%	0.244	C	C	.	.	H	α-helix	trans	-67.7	-43.8	176.7	0	0	0	0	0	112.1	L40 I44 L87 P88 F89 F93 E94 I95 W318	L40-A91 HydrophobicContact CB-CB 4.05Å; L40-A91 HydrophobicContact CD1-CB 3.85Å; I44-A91 HydrophobicContact CD1-CB 3.92Å; L87-A91 WeakPolarHBondContact O-CB 3.35Å; L87-A91 PolarHBondContact O-N 2.93Å; P88-A91 PolarHBondContact O-N 2.84Å; F89-A91 VanDerWaalsContact C-N 3.3Å; F89-A91 PolarHBondContact O-N 3.37Å; A91-F93 VanDerWaalsContact C-N 3.3Å; A91-F93 PolarHBondContact O-N 2.99Å; A91-E94 PolarHBondContact O-N 3.06Å; A91-I95 WeakPolarHBondContact O-CB 3.28Å; A91-I95 WeakPolarHBondContact O-CD1 3.44Å; A91-I95 WeakPolarHBondContact O-CG1 3.34Å; A91-I95 PolarHBondContact O-N 3.26Å; A91-W318 HydrophobicContact CB-CH2 4.3Å
92	V	91.1	Very high	90.5	Very high	52 Å²	52	45.7 Å²	45.7	32%	0.315	24%	0.242	S	C	.	.	H	α-helix	trans	-60.9	-41.7	174.7	171.9	0	0	0	0	111	P88 F89 I95 L96 F101	P88-V92 WeakPolarHBondContact O-CG2 3.49Å; P88-V92 PolarHBondContact O-N 3.5Å; F89-V92 PolarHBondContact O-N 3.18Å; V92-I95 PolarHBondContact O-N 3.49Å; V92-L96 HydrophobicContact CG1-CD1 3.6Å; V92-L96 HydrophobicContact CG1-CG 4.25Å; V92-L96 WeakPolarHBondContact O-CB 3.36Å; V92-L96 WeakPolarHBondContact O-CG 3.2Å; V92-L96 PolarHBondContact O-N 2.95Å; V92-F101 HydrophobicContact CB-CE2 4.29Å; V92-F101 HydrophobicContact CB-CZ 4.35Å; V92-F101 HydrophobicContact CG1-CE2 3.88Å; V92-F101 HydrophobicContact CG1-CZ 3.88Å
93	F	89.1	Confident	90	Very high	46 Å²	46	50.2 Å²	50.2	20%	0.202	26%	0.259	C	S	.	.	H	α-helix	trans	-62	-42.9	176	179.5	-119.4	0	0	0	112.1	F89 S90 A91 D97 W99	F89-F93 WeakPolarHBondContact O-CB 3.36Å; F89-F93 PolarHBondContact O-N 3.03Å; S90-F93 PolarHBondContact O-N 3.41Å; A91-F93 VanDerWaalsContact C-N 3.3Å; A91-F93 PolarHBondContact O-N 2.99Å; F93-D97 VanDerWaalsContact O-CA 3.3Å; F93-D97 WeakPolarHBondContact O-CA 3.42Å; F93-D97 PolarHBondContact O-N 3.09Å; F93-W99 HydrophobicContact CB-CE3 4.09Å; F93-W99 HydrophobicContact CB-CZ3 4.32Å; F93-W99 HydrophobicContact CD2-CB 4.06Å; F93-W99 AromaticContact CD2-CE3 3.92Å; F93-W99 HydrophobicContact CD2-CE3 3.92Å; F93-W99 HydrophobicContact CE2-CB 4.06Å; F93-W99 HydrophobicContact CG-CE3 4.1Å
94	E	88.3	Confident	89.6	Confident	44 Å²	44	54 Å²	54	21%	0.206	29%	0.29	C	S	.	.	H	α-helix	trans	-67.6	-34.7	177.3	-170.4	62.6	-143.6	0	0	112.8	L40 S90 A91 K314 W318	L40-E94 HydrophobicContact CD1-CB 4.41Å; L40-E94 HydrophobicContact CD1-CG 4.49Å; S90-E94 WeakPolarHBondContact O-CB 3.45Å; S90-E94 PolarHBondContact O-N 3.42Å; A91-E94 PolarHBondContact O-N 3.06Å; E94-K314 WeakPolarHBondContact OE1-CD 3.42Å; E94-K314 WeakPolarHBondContact OE1-CE 3.47Å; E94-K314 IonicContact OE1-NZ 3.77Å; E94-K314 PolarHBondContact OE1-NZ 3.28Å; E94-K314 VanDerWaalsContact OE2-CE 3.3Å; E94-K314 WeakPolarHBondContact OE2-CE 2.99Å; E94-K314 IonicContact OE2-NZ 3.35Å; E94-K314 PolarHBondContact OE2-NZ 3.44Å; E94-W318 HydrophobicContact CB-CZ2 4.42Å
95	I	88.4	Confident	89.4	Confident	57 Å²	57	54.6 Å²	54.6	29%	0.292	29%	0.286	S	S	.	.	H	α-helix	trans	-74	-43	-179.8	-70.8	165.8	0	0	0	111.4	T33 A91 V92	T33-I95 HydrophobicContact CG2-CG2 3.57Å; A91-I95 WeakPolarHBondContact O-CB 3.28Å; A91-I95 WeakPolarHBondContact O-CD1 3.44Å; A91-I95 WeakPolarHBondContact O-CG1 3.34Å; A91-I95 PolarHBondContact O-N 3.26Å; V92-I95 PolarHBondContact O-N 3.49Å
96	L	86.3	Confident	89.3	Confident	76 Å²	76	52.7 Å²	52.7	40%	0.398	27%	0.274	S	S	.	.	H	α-helix	trans	-86.3	-17.5	-177.2	-66.5	178	0	0	0	113	V92 R98 V100	V92-L96 HydrophobicContact CG1-CD1 3.6Å; V92-L96 HydrophobicContact CG1-CG 4.25Å; V92-L96 WeakPolarHBondContact O-CB 3.36Å; V92-L96 WeakPolarHBondContact O-CG 3.2Å; V92-L96 PolarHBondContact O-N 2.95Å; L96-R98 HydrophobicContact CB-CG 4.04Å; L96-R98 WeakPolarHBondContact O-CG 3.47Å; L96-R98 PolarHBondContact O-N 3.2Å; L96-V100 HydrophobicContact CD1-CG1 4.12Å; L96-V100 HydrophobicContact CD1-CG2 4.2Å
97	D	84.8	Confident	89	Confident	122 Å²	122	55.1 Å²	55.1	65%	0.652	29%	0.287	S	S	*	.	S	Bend	trans	53.8	21.3	-173	-147.6	35.7	0	0	0	113.1	F93 K314	F93-D97 VanDerWaalsContact O-CA 3.3Å; F93-D97 WeakPolarHBondContact O-CA 3.42Å; F93-D97 PolarHBondContact O-N 3.09Å; D97-K314 IonicContact OD1-NZ 3.94Å
98	R	85.8	Confident	88.9	Confident	150 Å²	150	58.8 Å²	58.8	57%	0.566	31%	0.309	S	S	*	.	S	Bend	trans	-151.8	143.8	178.6	66.3	-175.6	177.3	173.7	-0.5	110.5	L96 V100	L96-R98 HydrophobicContact CB-CG 4.04Å; L96-R98 WeakPolarHBondContact O-CG 3.47Å; L96-R98 PolarHBondContact O-N 3.2Å; R98-V100 HydrophobicContact CG-CG1 4.12Å
99	W	88.1	Confident	88.8	Confident	10 Å²	10	57.5 Å²	57.5	4%	0.038	30%	0.299	C	S	.	.			trans	-85.3	123.2	176.1	-172.6	-103	0	0	0	110.8	F93 F101 G102 F105 C106 W109 S181 C183	F93-W99 HydrophobicContact CB-CE3 4.09Å; F93-W99 HydrophobicContact CB-CZ3 4.32Å; F93-W99 HydrophobicContact CD2-CB 4.06Å; F93-W99 AromaticContact CD2-CE3 3.92Å; F93-W99 HydrophobicContact CD2-CE3 3.92Å; F93-W99 HydrophobicContact CE2-CB 4.06Å; F93-W99 HydrophobicContact CG-CE3 4.1Å; W99-F101 HydrophobicContact CD2-CD2 4.2Å; W99-F101 HydrophobicContact CE3-CD2 4.19Å; W99-F101 HydrophobicContact CH2-CD2 4.08Å; W99-F101 HydrophobicContact CZ2-CB 3.96Å; W99-F101 HydrophobicContact CZ2-CD2 4.11Å; W99-F101 HydrophobicContact CZ2-CG 4.48Å; W99-F101 HydrophobicContact CZ3-CD2 4.11Å; W99-G102 PolarHBondContact NE1-O 3Å; W99-F105 AromaticContact CH2-CD1 3.86Å; W99-F105 HydrophobicContact CH2-CD1 3.86Å; W99-F105 HydrophobicContact CH2-CE1 4.1Å; W99-F105 HydrophobicContact CZ2-CB 4.4Å; W99-F105 AromaticContact CZ2-CD1 3.43Å; W99-F105 HydrophobicContact CZ2-CD1 3.43Å; W99-F105 VanDerWaalsContact CZ2-CD1 3.43Å; W99-F105 HydrophobicContact CZ2-CE1 4.14Å; W99-F105 HydrophobicContact CZ2-CG 4.35Å; W99-C106 VanDerWaalsContact CZ2-CA 3.46Å; W99-C106 HydrophobicContact CZ2-CB 3.93Å; W99-W109 HydrophobicContact CH2-CB 3.97Å; W99-W109 AromaticContact CH2-CD2 3.93Å; W99-W109 HydrophobicContact CH2-CD2 3.93Å; W99-W109 HydrophobicContact CH2-CE3 4.26Å; W99-W109 AromaticContact CH2-CG 3.79Å; W99-W109 HydrophobicContact CH2-CG 3.79Å; W99-W109 HydrophobicContact CZ2-CB 4.38Å; W99-W109 HydrophobicContact CZ3-CD2 4.31Å; W99-S181 WeakPolarHBondContact CB-O 3.29Å; W99-S181 PolarHBondContact N-O 2.66Å; W99-C183 HydrophobicContact CB-CB 3.78Å; W99-C183 HydrophobicContact CD2-CB 3.51Å; W99-C183 HydrophobicContact CE3-CB 3.79Å; W99-C183 HydrophobicContact CG-CB 3.53Å
100	V	88.7	Confident	88.7	Confident	79 Å²	79	55.2 Å²	55.2	48%	0.479	29%	0.291	S	S	.	.			trans	-112	-4.8	-175.1	-62	0	0	0	0	114	L96 R98	L96-V100 HydrophobicContact CD1-CG1 4.12Å; L96-V100 HydrophobicContact CD1-CG2 4.2Å; R98-V100 HydrophobicContact CG-CG1 4.12Å
101	F	87.3	Confident	88.7	Confident	78 Å²	78	55.5 Å²	55.5	34%	0.342	29%	0.294	S	S	.	.	S	Bend	trans	-93.3	3.3	-172	-57.1	-75.3	0	0	0	113.7	F89 V92 W99 F105	F89-F101 HydrophobicContact CD1-CD1 4.39Å; F89-F101 HydrophobicContact CD1-CD2 4.2Å; F89-F101 HydrophobicContact CD1-CE1 4Å; F89-F101 AromaticContact CD1-CE2 3.8Å; F89-F101 HydrophobicContact CD1-CE2 3.8Å; F89-F101 HydrophobicContact CD1-CG 4.49Å; F89-F101 AromaticContact CD1-CZ 3.69Å; F89-F101 HydrophobicContact CD1-CZ 3.69Å; F89-F101 HydrophobicContact CE1-CD1 4.43Å; F89-F101 HydrophobicContact CE1-CE1 4.05Å; F89-F101 HydrophobicContact CE1-CZ 4.16Å; V92-F101 HydrophobicContact CB-CE2 4.29Å; V92-F101 HydrophobicContact CB-CZ 4.35Å; V92-F101 HydrophobicContact CG1-CE2 3.88Å; V92-F101 HydrophobicContact CG1-CZ 3.88Å; W99-F101 HydrophobicContact CD2-CD2 4.2Å; W99-F101 HydrophobicContact CE3-CD2 4.19Å; W99-F101 HydrophobicContact CH2-CD2 4.08Å; W99-F101 HydrophobicContact CZ2-CB 3.96Å; W99-F101 HydrophobicContact CZ2-CD2 4.11Å; W99-F101 HydrophobicContact CZ2-CG 4.48Å; W99-F101 HydrophobicContact CZ3-CD2 4.11Å; F101-F105 HydrophobicContact CB-CB 3.96Å; F101-F105 HydrophobicContact CB-CD1 3.36Å; F101-F105 HydrophobicContact CB-CE1 4.18Å; F101-F105 HydrophobicContact CB-CG 3.91Å; F101-F105 HydrophobicContact CD2-CD1 4.33Å; F101-F105 HydrophobicContact CD2-CE1 4.46Å; F101-F105 AromaticContact CG-CD1 3.86Å; F101-F105 HydrophobicContact CG-CD1 3.86Å; F101-F105 HydrophobicContact CG-CE1 4.19Å; F101-F105 VanDerWaalsContact O-CB 3.29Å; F101-F105 WeakPolarHBondContact O-CB 3.28Å
102	G	87.4	Confident	88.7	Confident	26 Å²	26	56.9 Å²	56.9	27%	0.268	30%	0.302	S	S	.	.	H	α-helix	trans	78.9	166.8	-179.9	0	0	0	0	0	114.6	W99 F105 C106	W99-G102 PolarHBondContact NE1-O 3Å; G102-F105 PolarHBondContact O-N 3.17Å; G102-C106 PolarHBondContact O-N 3.25Å
103	R	84.8	Confident	88.8	Confident	98 Å²	98	54.8 Å²	54.8	37%	0.37	29%	0.289	S	S	.	.	H	α-helix	trans	-67.2	-39.1	-171.3	-172.7	177.9	-80.4	-162.1	-7	114	F105 C106 N107 P177	R103-F105 VanDerWaalsContact C-N 3.35Å; R103-F105 PolarHBondContact O-N 3.09Å; R103-C106 WeakPolarHBondContact O-CB 3.45Å; R103-C106 PolarHBondContact O-N 3.31Å; R103-N107 PolarHBondContact O-N 3.44Å; R103-N107 VanDerWaalsContact O-N 3.16Å; R103-P177 PolarHBondContact NH2-O 3.39Å
104	A	87	Confident	89	Confident	78 Å²	78	53.6 Å²	53.6	65%	0.645	29%	0.285	S	S	*	.	H	α-helix	trans	-61.8	-43.9	178.8	0	0	0	0	0	111.6	C106 N107 V108	A104-C106 VanDerWaalsContact C-N 3.34Å; A104-C106 PolarHBondContact O-N 2.89Å; A104-N107 PolarHBondContact O-N 3.11Å; A104-V108 WeakPolarHBondContact O-CG2 3.47Å; A104-V108 PolarHBondContact O-N 2.96Å
105	F	90.3	Very high	89.2	Confident	69 Å²	69	52.9 Å²	52.9	30%	0.303	28%	0.283	S	S	.	.	H	α-helix	trans	-66.7	-36.2	177.3	-165.5	-104.6	0	0	0	111.7	F89 W99 F101 G102 R103 N107 V108 W109	F89-F105 HydrophobicContact CB-CE1 4.36Å; F89-F105 AromaticContact CD1-CE1 3.43Å; F89-F105 HydrophobicContact CD1-CE1 3.43Å; F89-F105 VanDerWaalsContact CD1-CE1 3.43Å; F89-F105 AromaticContact CD1-CZ 3.76Å; F89-F105 HydrophobicContact CD1-CZ 3.76Å; F89-F105 HydrophobicContact CD2-CE1 4.31Å; F89-F105 HydrophobicContact CD2-CZ 4.14Å; F89-F105 AromaticContact CE1-CE1 3.66Å; F89-F105 HydrophobicContact CE1-CE1 3.66Å; F89-F105 AromaticContact CE1-CZ 3.54Å; F89-F105 HydrophobicContact CE1-CZ 3.54Å; F89-F105 HydrophobicContact CE2-CE1 4.49Å; F89-F105 AromaticContact CE2-CZ 3.93Å; F89-F105 HydrophobicContact CE2-CZ 3.93Å; F89-F105 AromaticContact CG-CE1 3.77Å; F89-F105 HydrophobicContact CG-CE1 3.77Å; F89-F105 HydrophobicContact CG-CZ 4.04Å; F89-F105 HydrophobicContact CZ-CE1 4.19Å; F89-F105 AromaticContact CZ-CZ 3.63Å; F89-F105 HydrophobicContact CZ-CZ 3.63Å; W99-F105 AromaticContact CH2-CD1 3.86Å; W99-F105 HydrophobicContact CH2-CD1 3.86Å; W99-F105 HydrophobicContact CH2-CE1 4.1Å; W99-F105 HydrophobicContact CZ2-CB 4.4Å; W99-F105 AromaticContact CZ2-CD1 3.43Å; W99-F105 HydrophobicContact CZ2-CD1 3.43Å; W99-F105 VanDerWaalsContact CZ2-CD1 3.43Å; W99-F105 HydrophobicContact CZ2-CE1 4.14Å; W99-F105 HydrophobicContact CZ2-CG 4.35Å; F101-F105 HydrophobicContact CB-CB 3.96Å; F101-F105 HydrophobicContact CB-CD1 3.36Å; F101-F105 HydrophobicContact CB-CE1 4.18Å; F101-F105 HydrophobicContact CB-CG 3.91Å; F101-F105 HydrophobicContact CD2-CD1 4.33Å; F101-F105 HydrophobicContact CD2-CE1 4.46Å; F101-F105 AromaticContact CG-CD1 3.86Å; F101-F105 HydrophobicContact CG-CD1 3.86Å; F101-F105 HydrophobicContact CG-CE1 4.19Å; F101-F105 VanDerWaalsContact O-CB 3.29Å; F101-F105 WeakPolarHBondContact O-CB 3.28Å; G102-F105 PolarHBondContact O-N 3.17Å; R103-F105 VanDerWaalsContact C-N 3.35Å; R103-F105 PolarHBondContact O-N 3.09Å; F105-N107 VanDerWaalsContact C-N 3.34Å; F105-N107 PolarHBondContact O-N 3.4Å; F105-V108 PolarHBondContact O-N 2.95Å; F105-W109 HydrophobicContact CE1-CB 4.5Å; F105-W109 WeakPolarHBondContact O-CB 3.39Å; F105-W109 PolarHBondContact O-N 3.27Å
106	C	89.4	Confident	89.5	Confident	8 Å²	8	50.1 Å²	50.1	5%	0.054	27%	0.269	C	S	.	.	H	α-helix	trans	-58.3	-44.9	174.5	175.5	0	0	0	0	112.1	W99 G102 R103 A104 W109 A110 C183	W99-C106 VanDerWaalsContact CZ2-CA 3.46Å; W99-C106 HydrophobicContact CZ2-CB 3.93Å; G102-C106 PolarHBondContact O-N 3.25Å; R103-C106 WeakPolarHBondContact O-CB 3.45Å; R103-C106 PolarHBondContact O-N 3.31Å; A104-C106 VanDerWaalsContact C-N 3.34Å; A104-C106 PolarHBondContact O-N 2.89Å; C106-W109 PolarHBondContact O-N 3.22Å; C106-A110 WeakPolarHBondContact O-CB 3.28Å; C106-A110 PolarHBondContact O-N 3.19Å; C106-C183 VanDerWaalsContact CA-SG 3.56Å; C106-C183 HydrophobicContact CB-CB 3.87Å; C106-C183 WeakPolarHBondContact CB-SG 2.97Å; C106-C183 WeakPolarHBondContact SG-CA 3.29Å; C106-C183 WeakPolarHBondContact SG-CB 3.33Å; C106-C183 CovalentContact SG-SG 2.03Å; C106-C183 PolarHBondContact SG-SG 3.06Å
107	N	87.9	Confident	89.8	Confident	51 Å²	51	46.9 Å²	46.9	27%	0.273	25%	0.252	S	S	.	.	H	α-helix	trans	-65.6	-41.8	179.1	-68.8	-24.7	0	0	0	112	R103 A104 F105 A111 L169 K173	R103-N107 PolarHBondContact O-N 3.44Å; R103-N107 VanDerWaalsContact O-N 3.16Å; A104-N107 PolarHBondContact O-N 3.11Å; F105-N107 VanDerWaalsContact C-N 3.34Å; F105-N107 PolarHBondContact O-N 3.4Å; N107-A111 WeakPolarHBondContact O-CB 3.3Å; N107-A111 PolarHBondContact O-N 3.03Å; N107-L169 HydrophobicContact CB-CD2 4.01Å; N107-K173 PolarHBondContact OD1-NZ 3.43Å
108	V	90.8	Very high	90.2	Very high	77 Å²	77	41.1 Å²	41.1	47%	0.467	22%	0.222	S	C	.	.	H	α-helix	trans	-66.7	-46	176.3	175.1	0	0	0	0	110.8	A104 F105 A110 A111 V112	A104-V108 WeakPolarHBondContact O-CG2 3.47Å; A104-V108 PolarHBondContact O-N 2.96Å; F105-V108 PolarHBondContact O-N 2.95Å; V108-A110 PolarHBondContact O-N 2.97Å; V108-A111 PolarHBondContact O-N 3.37Å; V108-V112 HydrophobicContact CG1-CG2 4.16Å; V108-V112 WeakPolarHBondContact O-CB 3.41Å; V108-V112 VanDerWaalsContact O-CG2 3.27Å; V108-V112 WeakPolarHBondContact O-CG2 2.94Å; V108-V112 PolarHBondContact O-N 2.96Å
109	W	92.8	Very high	90.6	Very high	13 Å²	13	34 Å²	34	5%	0.049	20%	0.195	C	C	.	.	H	α-helix	trans	-57.7	-47.7	177.6	167.1	83.4	0	0	0	111.4	V86 S90 W99 F105 C106 A111 V112 D113 C183 I185	V86-W109 PolarHBondContact O-NE1 2.98Å; S90-W109 VanDerWaalsContact OG-CZ2 3.32Å; S90-W109 WeakPolarHBondContact OG-CZ2 3.44Å; S90-W109 PolarHBondContact OG-NE1 3.22Å; W99-W109 HydrophobicContact CH2-CB 3.97Å; W99-W109 AromaticContact CH2-CD2 3.93Å; W99-W109 HydrophobicContact CH2-CD2 3.93Å; W99-W109 HydrophobicContact CH2-CE3 4.26Å; W99-W109 AromaticContact CH2-CG 3.79Å; W99-W109 HydrophobicContact CH2-CG 3.79Å; W99-W109 HydrophobicContact CZ2-CB 4.38Å; W99-W109 HydrophobicContact CZ3-CD2 4.31Å; F105-W109 HydrophobicContact CE1-CB 4.5Å; F105-W109 WeakPolarHBondContact O-CB 3.39Å; F105-W109 PolarHBondContact O-N 3.27Å; C106-W109 PolarHBondContact O-N 3.22Å; W109-A111 PolarHBondContact O-N 2.95Å; W109-V112 PolarHBondContact O-N 3.49Å; W109-D113 WeakPolarHBondContact O-CB 3.44Å; W109-D113 PolarHBondContact O-N 3.46Å; W109-C183 VanDerWaalsContact CE3-SG 3.59Å; W109-I185 HydrophobicContact CH2-CG1 4.36Å; W109-I185 HydrophobicContact CZ3-CG1 4.27Å
110	A	90.2	Very high	90.9	Very high	12 Å²	12	33.7 Å²	33.7	10%	0.099	19%	0.194	C	C	.	.	H	α-helix	trans	-63.5	-39.6	177.7	0	0	0	0	0	112.3	C106 V108 D113 V114	C106-A110 WeakPolarHBondContact O-CB 3.28Å; C106-A110 PolarHBondContact O-N 3.19Å; V108-A110 PolarHBondContact O-N 2.97Å; A110-D113 PolarHBondContact O-N 3.41Å; A110-V114 WeakPolarHBondContact O-CG2 3.45Å; A110-V114 PolarHBondContact O-N 3.23Å; A110-V114 VanDerWaalsContact O-N 3.13Å
111	A	91.9	Very high	91.1	Very high	12 Å²	12	29.9 Å²	29.9	10%	0.099	17%	0.171	C	C	.	.	H	α-helix	trans	-66.4	-42.4	175.6	0	0	0	0	0	111.9	N107 V108 W109 V114 L115 S165 L169	N107-A111 WeakPolarHBondContact O-CB 3.3Å; N107-A111 PolarHBondContact O-N 3.03Å; V108-A111 PolarHBondContact O-N 3.37Å; W109-A111 PolarHBondContact O-N 2.95Å; A111-V114 PolarHBondContact O-N 3.14Å; A111-L115 VanDerWaalsContact O-CB 3.26Å; A111-L115 WeakPolarHBondContact O-CB 3.29Å; A111-L115 PolarHBondContact O-N 3.33Å; A111-S165 WeakPolarHBondContact O-CB 3.29Å; A111-L169 HydrophobicContact CB-CD1 4.33Å
112	V	93.5	Very high	91.4	Very high	37 Å²	37	27.8 Å²	27.8	22%	0.224	16%	0.162	C	C	.	.	H	α-helix	trans	-66.6	-38	177.4	173.7	0	0	0	0	111.3	V86 V108 W109 L115 C116	V86-V112 HydrophobicContact CG2-CB 4.48Å; V86-V112 HydrophobicContact CG2-CG1 3.78Å; V108-V112 HydrophobicContact CG1-CG2 4.16Å; V108-V112 WeakPolarHBondContact O-CB 3.41Å; V108-V112 VanDerWaalsContact O-CG2 3.27Å; V108-V112 WeakPolarHBondContact O-CG2 2.94Å; V108-V112 PolarHBondContact O-N 2.96Å; W109-V112 PolarHBondContact O-N 3.49Å; V112-L115 PolarHBondContact O-N 3.24Å; V112-C116 WeakPolarHBondContact O-CB 3.12Å; V112-C116 PolarHBondContact O-N 2.83Å; V112-C116 PolarHBondContact O-SG 3.16Å
113	D	92.7	Very high	91.7	Very high	7 Å²	7	26.7 Å²	26.7	4%	0.037	15%	0.151	C	C	.	.	H	α-helix	trans	-57.7	-54.2	173.7	-177.8	45.6	0	0	0	111.1	V86 W109 A110 L115 C116 C117 Y321	V86-D113 HydrophobicContact CG1-CB 3.88Å; V86-D113 WeakPolarHBondContact CG1-OD1 3.43Å; V86-D113 HydrophobicContact CG2-CB 4.42Å; W109-D113 WeakPolarHBondContact O-CB 3.44Å; W109-D113 PolarHBondContact O-N 3.46Å; A110-D113 PolarHBondContact O-N 3.41Å; D113-L115 VanDerWaalsContact C-N 3.35Å; D113-L115 PolarHBondContact O-N 3.24Å; D113-C116 PolarHBondContact O-N 2.94Å; D113-C117 WeakPolarHBondContact O-CB 3.33Å; D113-C117 PolarHBondContact O-N 2.89Å; D113-C117 PolarHBondContact O-SG 3.39Å; D113-Y321 VanDerWaalsContact OD1-CE1 3.27Å; D113-Y321 WeakPolarHBondContact OD1-CE1 3.28Å; D113-Y321 PolarHBondContact OD1-OH 2.93Å; D113-Y321 PolarHBondContact OD2-OH 2.68Å
114	V	91.8	Very high	91.9	Very high	22 Å²	22	22.3 Å²	22.3	13%	0.133	14%	0.135	C	C	.	.	H	α-helix	trans	-58.7	-47.3	176.3	176.3	0	0	0	0	110.7	A110 A111 C116 C117 T118 I164	A110-V114 WeakPolarHBondContact O-CG2 3.45Å; A110-V114 PolarHBondContact O-N 3.23Å; A110-V114 VanDerWaalsContact O-N 3.13Å; A111-V114 PolarHBondContact O-N 3.14Å; V114-C116 PolarHBondContact O-N 2.83Å; V114-C117 PolarHBondContact O-N 3.24Å; V114-T118 WeakPolarHBondContact O-CB 3.42Å; V114-T118 PolarHBondContact O-N 2.89Å; V114-T118 PolarHBondContact O-OG1 2.89Å; V114-I164 HydrophobicContact CG1-CG2 4.32Å
115	L	94.2	Very high	92.2	Very high	28 Å²	28	19.1 Å²	19.1	15%	0.147	11%	0.108	C	C	.	.	H	α-helix	trans	-55	-50.6	179.1	174.1	63.2	0	0	0	112.4	A111 V112 D113 A119 W158 I162	A111-L115 VanDerWaalsContact O-CB 3.26Å; A111-L115 WeakPolarHBondContact O-CB 3.29Å; A111-L115 PolarHBondContact O-N 3.33Å; V112-L115 PolarHBondContact O-N 3.24Å; D113-L115 VanDerWaalsContact C-N 3.35Å; D113-L115 PolarHBondContact O-N 3.24Å; L115-A119 VanDerWaalsContact O-CB 3.22Å; L115-A119 WeakPolarHBondContact O-CB 3.21Å; L115-A119 PolarHBondContact O-N 3.33Å; L115-W158 HydrophobicContact CD1-CE3 4.42Å; L115-W158 HydrophobicContact CG-CZ3 4.5Å; L115-I162 HydrophobicContact CD1-CB 4.39Å; L115-I162 HydrophobicContact CD1-CG1 3.62Å
116	C	94.1	Very high	92.3	Very high	0 Å²	0	17.3 Å²	17.3	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-67.7	-40.6	-177.1	-63.7	0	0	0	0	111.5	L81 L82 V112 D113 V114 S120	L81-C116 WeakPolarHBondContact CD2-SG 3.44Å; L81-C116 VanDerWaalsContact CG-SG 3.52Å; L82-C116 HydrophobicContact CB-CB 3.91Å; L82-C116 HydrophobicContact CD1-CB 3.97Å; V112-C116 WeakPolarHBondContact O-CB 3.12Å; V112-C116 PolarHBondContact O-N 2.83Å; V112-C116 PolarHBondContact O-SG 3.16Å; D113-C116 PolarHBondContact O-N 2.94Å; V114-C116 PolarHBondContact O-N 2.83Å; C116-S120 WeakPolarHBondContact O-CB 3.37Å; C116-S120 PolarHBondContact O-N 3.49Å; C116-S120 PolarHBondContact O-OG 3.29Å
117	C	91.8	Very high	92.4	Very high	8 Å²	8	17.2 Å²	17.2	5%	0.054	10%	0.101	C	C	.	.	H	α-helix	trans	-63.9	-51.5	177	-64.3	0	0	0	0	110.4	D113 V114 A119 S120 I121 W290	D113-C117 WeakPolarHBondContact O-CB 3.33Å; D113-C117 PolarHBondContact O-N 2.89Å; D113-C117 PolarHBondContact O-SG 3.39Å; V114-C117 PolarHBondContact O-N 3.24Å; C117-A119 VanDerWaalsContact C-N 3.35Å; C117-A119 PolarHBondContact O-N 3.49Å; C117-S120 PolarHBondContact O-N 3.27Å; C117-S120 VanDerWaalsContact O-N 3.16Å; C117-I121 VanDerWaalsContact O-CG1 3.28Å; C117-I121 WeakPolarHBondContact O-CG1 3.13Å; C117-I121 PolarHBondContact O-N 3.49Å; C117-W290 HydrophobicContact CB-CH2 3.91Å; C117-W290 HydrophobicContact CB-CZ2 4.4Å; C117-W290 HydrophobicContact CB-CZ3 4.48Å; C117-W290 WeakPolarHBondContact SG-CH2 3.48Å
118	T	93.6	Very high	92.5	Very high	1 Å²	1	14.9 Å²	14.9	1%	0.006	9%	0.088	C	C	.	.	H	α-helix	trans	-58.8	-44.8	177.3	-53.4	0	0	0	0	111.6	V114 S120 I121 M122 I164 S199	V114-T118 WeakPolarHBondContact O-CB 3.42Å; V114-T118 PolarHBondContact O-N 2.89Å; V114-T118 PolarHBondContact O-OG1 2.89Å; T118-S120 VanDerWaalsContact C-N 3.3Å; T118-S120 PolarHBondContact O-N 3.41Å; T118-I121 PolarHBondContact O-N 3.42Å; T118-M122 HydrophobicContact CG2-CG 4.15Å; T118-M122 VanDerWaalsContact O-CB 3.3Å; T118-M122 WeakPolarHBondContact O-CB 2.97Å; T118-M122 VanDerWaalsContact O-CG 3.22Å; T118-M122 WeakPolarHBondContact O-CG 3.33Å; T118-M122 PolarHBondContact O-N 2.67Å; T118-I164 HydrophobicContact CG2-CD1 3.89Å; T118-S199 WeakPolarHBondContact CG2-OG 3.2Å; T118-S199 VanDerWaalsContact OG1-CB 3.31Å; T118-S199 WeakPolarHBondContact OG1-CB 3.23Å; T118-S199 PolarHBondContact OG1-OG 2.95Å
119	A	95.3	Very high	92.5	Very high	0 Å²	0	13.4 Å²	13.4	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-60.8	-38.5	178.2	0	0	0	0	0	112.3	A78 L115 C117 S123 L157 W158 S161	A78-A119 HydrophobicContact CB-CB 4.17Å; L115-A119 VanDerWaalsContact O-CB 3.22Å; L115-A119 WeakPolarHBondContact O-CB 3.21Å; L115-A119 PolarHBondContact O-N 3.33Å; C117-A119 VanDerWaalsContact C-N 3.35Å; C117-A119 PolarHBondContact O-N 3.49Å; A119-S123 VanDerWaalsContact O-CB 3.27Å; A119-S123 WeakPolarHBondContact O-CB 3.34Å; A119-S123 PolarHBondContact O-N 3.47Å; A119-S123 PolarHBondContact O-OG 3.01Å; A119-L157 HydrophobicContact CB-CD1 4.35Å; A119-W158 HydrophobicContact CB-CE3 4.24Å; A119-W158 HydrophobicContact CB-CH2 4.15Å; A119-W158 HydrophobicContact CB-CZ3 4.01Å; A119-S161 WeakPolarHBondContact CA-OG 3.41Å; A119-S161 PolarHBondContact N-OG 2.89Å
120	S	93.4	Very high	92.4	Very high	3 Å²	3	12.8 Å²	12.8	2%	0.021	8%	0.077	C	C	.	.	H	α-helix	trans	-68.3	-45.1	178.5	-58.1	0	0	0	0	111.8	A78 C116 C117 T118 S123 L124	A78-S120 WeakPolarHBondContact CB-OG 3.42Å; C116-S120 WeakPolarHBondContact O-CB 3.37Å; C116-S120 PolarHBondContact O-N 3.49Å; C116-S120 PolarHBondContact O-OG 3.29Å; C117-S120 PolarHBondContact O-N 3.27Å; C117-S120 VanDerWaalsContact O-N 3.16Å; T118-S120 VanDerWaalsContact C-N 3.3Å; T118-S120 PolarHBondContact O-N 3.41Å; S120-S123 WeakPolarHBondContact O-CB 3.47Å; S120-S123 PolarHBondContact O-N 2.91Å; S120-L124 PolarHBondContact O-N 2.94Å
121	I	92.7	Very high	92.2	Very high	0 Å²	0	13.3 Å²	13.3	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-66.5	-44.8	178.5	-56	174.9	0	0	0	111.1	C117 T118 S123 L124 C125 S199 F200 P203 F286 F294	C117-I121 VanDerWaalsContact O-CG1 3.28Å; C117-I121 WeakPolarHBondContact O-CG1 3.13Å; C117-I121 PolarHBondContact O-N 3.49Å; T118-I121 PolarHBondContact O-N 3.42Å; I121-S123 VanDerWaalsContact C-N 3.27Å; I121-S123 PolarHBondContact O-N 3.23Å; I121-L124 WeakPolarHBondContact O-CB 3.49Å; I121-L124 PolarHBondContact O-N 3.49Å; I121-L124 VanDerWaalsContact O-N 3.15Å; I121-C125 PolarHBondContact O-N 2.9Å; I121-S199 WeakPolarHBondContact CB-O 3.45Å; I121-S199 VanDerWaalsContact CD1-O 3.26Å; I121-S199 WeakPolarHBondContact CD1-O 3.49Å; I121-S199 VanDerWaalsContact CG2-O 3.23Å; I121-S199 WeakPolarHBondContact CG2-O 3.32Å; I121-F200 HydrophobicContact CD1-CD2 4.26Å; I121-P203 HydrophobicContact CG2-CB 3.64Å; I121-P203 HydrophobicContact CG2-CG 4.26Å; I121-F286 HydrophobicContact CB-CE2 4.36Å; I121-F286 HydrophobicContact CB-CZ 4.05Å; I121-F286 HydrophobicContact CD1-CE2 4.23Å; I121-F286 HydrophobicContact CD1-CZ 3.9Å; I121-F286 HydrophobicContact CG1-CE2 3.57Å; I121-F286 HydrophobicContact CG1-CZ 3.5Å; I121-F286 VanDerWaalsContact CG1-CZ 3.5Å; I121-F286 HydrophobicContact CG2-CE1 4.19Å; I121-F286 HydrophobicContact CG2-CE2 4.34Å; I121-F286 HydrophobicContact CG2-CZ 3.58Å; I121-F294 HydrophobicContact CD1-CE2 3.91Å; I121-F294 HydrophobicContact CD1-CZ 4.09Å
122	M	93.3	Very high	92	Very high	33 Å²	33	15.3 Å²	15.3	16%	0.163	8%	0.082	C	C	.	.	H	α-helix	trans	-62.9	-35.4	176.3	-71.1	-64.4	-73.7	0	0	111.7	T118 C125 V126 L157 L160 P203	T118-M122 HydrophobicContact CG2-CG 4.15Å; T118-M122 VanDerWaalsContact O-CB 3.3Å; T118-M122 WeakPolarHBondContact O-CB 2.97Å; T118-M122 VanDerWaalsContact O-CG 3.22Å; T118-M122 WeakPolarHBondContact O-CG 3.33Å; T118-M122 PolarHBondContact O-N 2.67Å; M122-C125 WeakPolarHBondContact O-CB 3.27Å; M122-C125 PolarHBondContact O-N 2.94Å; M122-V126 WeakPolarHBondContact O-CG2 3.27Å; M122-V126 PolarHBondContact O-N 3.24Å; M122-L157 HydrophobicContact CB-CB 4.15Å; M122-L160 HydrophobicContact CE-CD1 3.94Å; M122-P203 HydrophobicContact SD-CB 4.24Å; M122-P203 HydrophobicContact SD-CG 3.52Å; M122-P203 VanDerWaalsContact SD-CG 3.52Å
123	S	93.4	Very high	91.8	Very high	3 Å²	3	14.7 Å²	14.7	2%	0.021	8%	0.077	C	C	.	.	H	α-helix	trans	-63.1	-43.3	172.8	-64	0	0	0	0	112	N74 A119 S120 I121 C125 V126 I127	N74-S123 PolarHBondContact ND2-OG 2.88Å; A119-S123 VanDerWaalsContact O-CB 3.27Å; A119-S123 WeakPolarHBondContact O-CB 3.34Å; A119-S123 PolarHBondContact O-N 3.47Å; A119-S123 PolarHBondContact O-OG 3.01Å; S120-S123 WeakPolarHBondContact O-CB 3.47Å; S120-S123 PolarHBondContact O-N 2.91Å; I121-S123 VanDerWaalsContact C-N 3.27Å; I121-S123 PolarHBondContact O-N 3.23Å; S123-C125 VanDerWaalsContact C-N 3.3Å; S123-C125 PolarHBondContact O-N 3.01Å; S123-V126 PolarHBondContact O-N 3.34Å; S123-I127 WeakPolarHBondContact O-CB 3.22Å; S123-I127 WeakPolarHBondContact O-CG1 3.4Å; S123-I127 PolarHBondContact O-N 2.92Å
124	L	90	Very high	91.4	Very high	7 Å²	7	14.5 Å²	14.5	4%	0.037	8%	0.077	C	C	.	.	H	α-helix	trans	-61.9	-38.6	173.9	-71.7	172.7	0	0	0	112	L75 S120 I121 I127 S128 I207 V282 F286	L75-L124 HydrophobicContact CD1-CG 4.47Å; L75-L124 HydrophobicContact CD2-CD2 3.63Å; L75-L124 HydrophobicContact CD2-CG 4.16Å; S120-L124 PolarHBondContact O-N 2.94Å; I121-L124 WeakPolarHBondContact O-CB 3.49Å; I121-L124 PolarHBondContact O-N 3.49Å; I121-L124 VanDerWaalsContact O-N 3.15Å; L124-I127 PolarHBondContact O-N 2.92Å; L124-S128 WeakPolarHBondContact O-CB 3.44Å; L124-S128 PolarHBondContact O-N 3.39Å; L124-S128 PolarHBondContact O-OG 2.79Å; L124-I207 HydrophobicContact CB-CD1 4.21Å; L124-V282 HydrophobicContact CD2-CG1 3.7Å; L124-F286 HydrophobicContact CD1-CB 3.98Å; L124-F286 HydrophobicContact CD1-CD1 4.27Å; L124-F286 HydrophobicContact CD1-CD2 3.26Å; L124-F286 HydrophobicContact CD1-CE2 3.83Å; L124-F286 HydrophobicContact CD1-CG 3.53Å
125	C	92.7	Very high	90.9	Very high	11 Å²	11	14.1 Å²	14.1	7%	0.074	7%	0.074	C	C	.	.	H	α-helix	trans	-60.1	-49.4	174	-177.4	0	0	0	0	111.8	I121 M122 S123 I127 S128 V129 P203 I206 I207	I121-C125 PolarHBondContact O-N 2.9Å; M122-C125 WeakPolarHBondContact O-CB 3.27Å; M122-C125 PolarHBondContact O-N 2.94Å; S123-C125 VanDerWaalsContact C-N 3.3Å; S123-C125 PolarHBondContact O-N 3.01Å; C125-I127 VanDerWaalsContact C-N 3.35Å; C125-I127 PolarHBondContact O-N 3.38Å; C125-S128 VanDerWaalsContact O-CB 3.29Å; C125-S128 WeakPolarHBondContact O-CB 3.41Å; C125-S128 PolarHBondContact O-N 3.48Å; C125-S128 VanDerWaalsContact O-N 3.09Å; C125-V129 PolarHBondContact O-N 2.94Å; C125-P203 HydrophobicContact CB-CB 4.3Å; C125-I206 WeakPolarHBondContact SG-CG2 3.26Å; C125-I207 HydrophobicContact CB-CD1 4.24Å; C125-I207 HydrophobicContact CB-CG1 4.03Å
126	V	93.2	Very high	90.3	Very high	30 Å²	30	14 Å²	14	18%	0.182	8%	0.076	C	C	.	.	H	α-helix	trans	-62.2	-41.5	176.7	173.2	0	0	0	0	111.6	F71 M122 S123 S128 V129 D130 A153 L157	F71-V126 HydrophobicContact CD1-CG1 3.73Å; F71-V126 HydrophobicContact CD2-CG1 4.4Å; F71-V126 HydrophobicContact CE1-CG1 3.45Å; F71-V126 VanDerWaalsContact CE1-CG1 3.45Å; F71-V126 HydrophobicContact CE2-CG1 4.16Å; F71-V126 HydrophobicContact CG-CG1 4.21Å; F71-V126 HydrophobicContact CZ-CG1 3.68Å; M122-V126 WeakPolarHBondContact O-CG2 3.27Å; M122-V126 PolarHBondContact O-N 3.24Å; S123-V126 PolarHBondContact O-N 3.34Å; V126-S128 VanDerWaalsContact C-N 3.29Å; V126-S128 PolarHBondContact O-N 2.98Å; V126-V129 PolarHBondContact O-N 3.3Å; V126-D130 PolarHBondContact O-N 3.4Å; V126-A153 HydrophobicContact CG1-CB 4.42Å; V126-L157 HydrophobicContact CG2-CD2 4.46Å
127	I	91.3	Very high	89.8	Confident	7 Å²	7	19.4 Å²	19.4	4%	0.036	10%	0.097	C	C	.	.	H	α-helix	trans	-58	-44.9	173.5	-69.3	164.1	0	0	0	109.6	F71 L75 S123 L124 C125 V129 D130 R131 L279	F71-I127 HydrophobicContact CB-CD1 4.29Å; F71-I127 HydrophobicContact CB-CG1 3.62Å; L75-I127 HydrophobicContact CB-CD1 4.45Å; L75-I127 HydrophobicContact CD2-CD1 3.91Å; S123-I127 WeakPolarHBondContact O-CB 3.22Å; S123-I127 WeakPolarHBondContact O-CG1 3.4Å; S123-I127 PolarHBondContact O-N 2.92Å; L124-I127 PolarHBondContact O-N 2.92Å; C125-I127 VanDerWaalsContact C-N 3.35Å; C125-I127 PolarHBondContact O-N 3.38Å; I127-V129 VanDerWaalsContact C-N 3.32Å; I127-V129 PolarHBondContact O-N 3.38Å; I127-D130 PolarHBondContact O-N 2.85Å; I127-R131 HydrophobicContact CG2-CG 4.08Å; I127-R131 WeakPolarHBondContact O-CB 3.03Å; I127-R131 WeakPolarHBondContact O-CG 3.34Å; I127-R131 PolarHBondContact O-N 2.91Å; I127-L279 HydrophobicContact CG2-CD2 3.87Å
128	S	90	Very high	89.1	Confident	1 Å²	1	20.3 Å²	20.3	1%	0.007	10%	0.103	C	C	.	.	H	α-helix	trans	-59.4	-42.6	179.7	-51	0	0	0	0	112.3	L124 C125 V126 R131 Y132 Y211	L124-S128 WeakPolarHBondContact O-CB 3.44Å; L124-S128 PolarHBondContact O-N 3.39Å; L124-S128 PolarHBondContact O-OG 2.79Å; C125-S128 VanDerWaalsContact O-CB 3.29Å; C125-S128 WeakPolarHBondContact O-CB 3.41Å; C125-S128 PolarHBondContact O-N 3.48Å; C125-S128 VanDerWaalsContact O-N 3.09Å; V126-S128 VanDerWaalsContact C-N 3.29Å; V126-S128 PolarHBondContact O-N 2.98Å; S128-R131 PolarHBondContact O-N 3.45Å; S128-Y132 PolarHBondContact O-N 3.26Å; S128-Y211 WeakPolarHBondContact OG-CE2 3.42Å
129	V	91.4	Very high	88.3	Confident	47 Å²	47	24.3 Å²	24.3	29%	0.285	12%	0.124	S	C	.	.	H	α-helix	trans	-66.9	-45.7	175.8	175.5	0	0	0	0	111.6	C125 V126 I127 R131 Y132 I133 I206 M210	C125-V129 PolarHBondContact O-N 2.94Å; V126-V129 PolarHBondContact O-N 3.3Å; I127-V129 VanDerWaalsContact C-N 3.32Å; I127-V129 PolarHBondContact O-N 3.38Å; V129-R131 PolarHBondContact O-N 3.38Å; V129-Y132 PolarHBondContact O-N 3.02Å; V129-I133 HydrophobicContact CG1-CD1 3.94Å; V129-I133 WeakPolarHBondContact O-CG1 3.22Å; V129-I133 PolarHBondContact O-N 3.45Å; V129-I206 HydrophobicContact CG2-CG2 4.36Å; V129-M210 HydrophobicContact CG2-CG 3.93Å; V129-M210 HydrophobicContact CG2-SD 4.27Å
130	D	90.3	Very high	87.7	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-55.3	-42	175.4	173.9	75.9	0	0	0	111.2	T68 F71 V126 I127 I133 G134 Y141	T68-D130 WeakPolarHBondContact CG2-OD2 3.34Å; T68-D130 PolarHBondContact OG1-OD2 3.36Å; F71-D130 HydrophobicContact CD2-CB 4.15Å; F71-D130 HydrophobicContact CE2-CB 3.94Å; V126-D130 PolarHBondContact O-N 3.4Å; I127-D130 PolarHBondContact O-N 2.85Å; D130-I133 PolarHBondContact O-N 3.26Å; D130-G134 PolarHBondContact O-N 3.17Å; D130-Y141 VanDerWaalsContact OD1-CE2 3.26Å; D130-Y141 WeakPolarHBondContact OD1-CE2 3.5Å; D130-Y141 PolarHBondContact OD1-OH 3.2Å
131	R	86.4	Confident	87.3	Confident	22 Å²	22	34.3 Å²	34.3	8%	0.083	16%	0.161	C	C	.	.	H	α-helix	trans	-72.2	-38.4	-178.7	-62.1	-70.2	89.1	-148.6	-5.2	111.9	T68 I127 S128 V129 I133 G134 V135 E272 L279	T68-R131 PolarHBondContact OG1-NH2 3.42Å; I127-R131 HydrophobicContact CG2-CG 4.08Å; I127-R131 WeakPolarHBondContact O-CB 3.03Å; I127-R131 WeakPolarHBondContact O-CG 3.34Å; I127-R131 PolarHBondContact O-N 2.91Å; S128-R131 PolarHBondContact O-N 3.45Å; V129-R131 PolarHBondContact O-N 3.38Å; R131-I133 PolarHBondContact O-N 3.37Å; R131-G134 PolarHBondContact O-N 3.08Å; R131-V135 WeakPolarHBondContact O-CB 3.41Å; R131-V135 WeakPolarHBondContact O-CG2 3.39Å; R131-V135 PolarHBondContact O-N 2.67Å; R131-E272 IonicContact NH1-OE2 3.11Å; R131-E272 PolarHBondContact NH1-OE2 3.5Å; R131-E272 VanDerWaalsContact NH1-OE2 3.16Å; R131-L279 HydrophobicContact CB-CD1 3.89Å; R131-L279 HydrophobicContact CG-CD1 3.34Å; R131-L279 HydrophobicContact CG-CD2 4.01Å; R131-L279 HydrophobicContact CG-CG 4.26Å
132	Y	87.5	Confident	86.8	Confident	54 Å²	54	38.6 Å²	38.6	21%	0.212	19%	0.19	C	C	.	.	H	α-helix	trans	-57.3	-46.8	170	171.6	-110.9	0	0	0	112.4	S128 V129 V135 S136 M210 R213 V214	S128-Y132 PolarHBondContact O-N 3.26Å; V129-Y132 PolarHBondContact O-N 3.02Å; Y132-V135 PolarHBondContact O-N 3.33Å; Y132-S136 VanDerWaalsContact CD2-OG 3.28Å; Y132-S136 WeakPolarHBondContact CD2-OG 3.38Å; Y132-S136 WeakPolarHBondContact CE2-OG 3.26Å; Y132-S136 WeakPolarHBondContact O-CB 3.45Å; Y132-S136 PolarHBondContact O-N 2.94Å; Y132-S136 PolarHBondContact O-OG 3.36Å; Y132-M210 HydrophobicContact CD1-SD 3.85Å; Y132-M210 HydrophobicContact CG-SD 4.02Å; Y132-R213 HydrophobicContact CD2-CB 3.76Å; Y132-R213 HydrophobicContact CE2-CB 3.56Å; Y132-R213 HydrophobicContact CE2-CG 4.45Å; Y132-V214 HydrophobicContact CD2-CG2 4.08Å; Y132-V214 HydrophobicContact CG-CG2 4.48Å
133	I	88.5	Confident	86.4	Confident	25 Å²	25	41 Å²	41	13%	0.128	21%	0.21	C	C	.	.	H	α-helix	trans	-66.5	-41	179.2	-62.3	164.8	0	0	0	110.7	V129 D130 R131 Y137 Y141 I144 M145	V129-I133 HydrophobicContact CG1-CD1 3.94Å; V129-I133 WeakPolarHBondContact O-CG1 3.22Å; V129-I133 PolarHBondContact O-N 3.45Å; D130-I133 PolarHBondContact O-N 3.26Å; R131-I133 PolarHBondContact O-N 3.37Å; I133-Y137 PolarHBondContact O-N 2.81Å; I133-Y141 HydrophobicContact CG2-CD2 4.07Å; I133-I144 HydrophobicContact CD1-CG2 4.5Å; I133-I144 HydrophobicContact CG2-CB 4.29Å; I133-I144 HydrophobicContact CG2-CD1 4.11Å; I133-I144 HydrophobicContact CG2-CG2 3.91Å; I133-M145 HydrophobicContact CD1-CE 3.52Å
134	G	85	Confident	86.2	Confident	2 Å²	2	43.3 Å²	43.3	2%	0.021	22%	0.221	C	C	.	.	H	α-helix	trans	-63.1	-41.4	178.2	0	0	0	0	0	113.6	D130 R131 P138 Y141	D130-G134 PolarHBondContact O-N 3.17Å; R131-G134 PolarHBondContact O-N 3.08Å; G134-P138 WeakPolarHBondContact O-CA 3.38Å; G134-Y141 VanDerWaalsContact CA-CD2 3.48Å
135	V	81.4	Confident	86.1	Confident	14 Å²	14	44.4 Å²	44.4	9%	0.085	23%	0.227	C	C	.	.	H	α-helix	trans	-76.7	-41	179	173.8	0	0	0	0	111.6	R131 Y132 V214 V217 A276	R131-V135 WeakPolarHBondContact O-CB 3.41Å; R131-V135 WeakPolarHBondContact O-CG2 3.39Å; R131-V135 PolarHBondContact O-N 2.67Å; Y132-V135 PolarHBondContact O-N 3.33Å; V135-V214 HydrophobicContact CG1-CG1 4.41Å; V135-V214 HydrophobicContact CG2-CG1 4.32Å; V135-V217 HydrophobicContact CG1-CG1 4.25Å; V135-A276 HydrophobicContact CG2-CB 4.41Å
136	S	82.2	Confident	86	Confident	26 Å²	26	46.4 Å²	46.4	18%	0.182	24%	0.238	C	C	.	.	H	α-helix	trans	-76.9	-32	-176.2	-53.5	0	0	0	0	113.2	Y132	Y132-S136 VanDerWaalsContact CD2-OG 3.28Å; Y132-S136 WeakPolarHBondContact CD2-OG 3.38Å; Y132-S136 WeakPolarHBondContact CE2-OG 3.26Å; Y132-S136 WeakPolarHBondContact O-CB 3.45Å; Y132-S136 PolarHBondContact O-N 2.94Å; Y132-S136 PolarHBondContact O-OG 3.36Å
137	Y	81.8	Confident	85.8	Confident	113 Å²	113	51.6 Å²	51.6	44%	0.443	26%	0.259	S	S	.	.			trans	-137	61.9	-174	-53.6	-72.7	0	0	0	112.6	I133 L139 R140 Y141	I133-Y137 PolarHBondContact O-N 2.81Å; Y137-L139 PolarHBondContact O-N 3.31Å; Y137-L139 VanDerWaalsContact O-N 3.07Å; Y137-R140 CarbonylContact O-C 3.38Å; Y137-R140 PolarHBondContact O-N 3.18Å; Y137-R140 VanDerWaalsContact O-N 3.1Å; Y137-Y141 WeakPolarHBondContact O-CB 3.22Å; Y137-Y141 PolarHBondContact O-N 3.46Å
138	P	77.3	Confident	85.7	Confident	28 Å²	28	61.7 Å²	61.7	18%	0.182	30%	0.296	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63.2	-23.9	-170.8	25.4	-36.6	0	0	0	115	G134 F269	G134-P138 WeakPolarHBondContact O-CA 3.38Å; P138-F269 HydrophobicContact CB-CE1 4.48Å; P138-F269 HydrophobicContact CG-CD1 4.13Å; P138-F269 HydrophobicContact CG-CE1 3.39Å; P138-F269 HydrophobicContact CG-CE2 4.05Å; P138-F269 HydrophobicContact CG-CZ 3.32Å
139	L	78.1	Confident	85.8	Confident	85 Å²	85	68.7 Å²	68.7	45%	0.445	32%	0.322	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.2	-31.5	178.3	-60.9	166.8	0	0	0	112.7	Y137 R265	Y137-L139 PolarHBondContact O-N 3.31Å; Y137-L139 VanDerWaalsContact O-N 3.07Å; L139-R265 VanDerWaalsContact CD1-NE 3.35Å; L139-R265 HydrophobicContact CD2-CG 4.22Å
140	R	82	Confident	85.8	Confident	174 Å²	174	66.7 Å²	66.7	66%	0.657	31%	0.311	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.2	-10.8	177.4	-61.8	-176	177.6	-178.6	-0.3	112	Y137 S143 I144	Y137-R140 CarbonylContact O-C 3.38Å; Y137-R140 PolarHBondContact O-N 3.18Å; Y137-R140 VanDerWaalsContact O-N 3.1Å; R140-S143 PolarHBondContact O-N 2.84Å; R140-S143 VanDerWaalsContact O-N 3.07Å; R140-S143 PolarHBondContact O-OG 2.61Å; R140-I144 HydrophobicContact CB-CD1 3.74Å; R140-I144 HydrophobicContact CB-CG1 4.32Å; R140-I144 VanDerWaalsContact O-CG1 3.26Å; R140-I144 WeakPolarHBondContact O-CG1 3.39Å; R140-I144 PolarHBondContact O-N 2.98Å
141	Y	85.6	Confident	85.9	Confident	38 Å²	38	72 Å²	72	15%	0.149	34%	0.339	C	S	.	.	H	α-helix	trans	-50.4	-48.1	178.1	175.6	-93.5	0	0	0	113.2	T68 D130 I133 G134 Y137 S143 I144 M145	T68-Y141 PolarHBondContact OG1-OH 2.92Å; T68-Y141 VanDerWaalsContact OG1-OH 3.11Å; D130-Y141 VanDerWaalsContact OD1-CE2 3.26Å; D130-Y141 WeakPolarHBondContact OD1-CE2 3.5Å; D130-Y141 PolarHBondContact OD1-OH 3.2Å; I133-Y141 HydrophobicContact CG2-CD2 4.07Å; G134-Y141 VanDerWaalsContact CA-CD2 3.48Å; Y137-Y141 WeakPolarHBondContact O-CB 3.22Å; Y137-Y141 PolarHBondContact O-N 3.46Å; Y141-S143 VanDerWaalsContact C-N 3.26Å; Y141-S143 PolarHBondContact O-N 2.87Å; Y141-I144 PolarHBondContact O-N 3.33Å; Y141-M145 HydrophobicContact CD2-CB 4.32Å; Y141-M145 HydrophobicContact CD2-CG 4.35Å; Y141-M145 HydrophobicContact CE1-CB 4.48Å; Y141-M145 HydrophobicContact CE2-CB 3.84Å; Y141-M145 HydrophobicContact CE2-CG 3.82Å; Y141-M145 PolarHBondContact O-N 3.3Å
142	P	82.4	Confident	86.2	Confident	91 Å²	91	76.1 Å²	76.1	59%	0.591	36%	0.362	S	S	*	.	H	α-helix	trans	-65.4	-25.4	-179	-20.8	34.1	0	0	0	114.3
143	S	84.9	Confident	86.5	Confident	84 Å²	84	74.9 Å²	74.9	59%	0.587	36%	0.363	S	S	*	.	H	α-helix	trans	-86.9	-29.7	176.1	62.8	0	0	0	0	112.5	R140 Y141	R140-S143 PolarHBondContact O-N 2.84Å; R140-S143 VanDerWaalsContact O-N 3.07Å; R140-S143 PolarHBondContact O-OG 2.61Å; Y141-S143 VanDerWaalsContact C-N 3.26Å; Y141-S143 PolarHBondContact O-N 2.87Å
144	I	87.8	Confident	86.8	Confident	50 Å²	50	74.8 Å²	74.8	26%	0.256	36%	0.363	S	S	.	.	H	α-helix	trans	-77.3	-51	178.4	-63.7	164.8	0	0	0	110.9	I133 R140 Y141 T146 R149	I133-I144 HydrophobicContact CD1-CG2 4.5Å; I133-I144 HydrophobicContact CG2-CB 4.29Å; I133-I144 HydrophobicContact CG2-CD1 4.11Å; I133-I144 HydrophobicContact CG2-CG2 3.91Å; R140-I144 HydrophobicContact CB-CD1 3.74Å; R140-I144 HydrophobicContact CB-CG1 4.32Å; R140-I144 VanDerWaalsContact O-CG1 3.26Å; R140-I144 WeakPolarHBondContact O-CG1 3.39Å; R140-I144 PolarHBondContact O-N 2.98Å; Y141-I144 PolarHBondContact O-N 3.33Å; I144-T146 PolarHBondContact O-N 3.49Å; I144-R149 VanDerWaalsContact O-CD 3.32Å; I144-R149 WeakPolarHBondContact O-CD 3.29Å; I144-R149 PolarHBondContact O-NH1 3.16Å
145	M	88.2	Confident	87.3	Confident	31 Å²	31	80.6 Å²	80.6	15%	0.153	39%	0.392	C	S	.	.	S	Bend	trans	-96.3	86.3	-176	-83.3	-61.2	177.8	0	0	111.4	V67 I133 Y141	V67-M145 HydrophobicContact CG1-CB 4.47Å; I133-M145 HydrophobicContact CD1-CE 3.52Å; Y141-M145 HydrophobicContact CD2-CB 4.32Å; Y141-M145 HydrophobicContact CD2-CG 4.35Å; Y141-M145 HydrophobicContact CE1-CB 4.48Å; Y141-M145 HydrophobicContact CE2-CB 3.84Å; Y141-M145 HydrophobicContact CE2-CG 3.82Å; Y141-M145 PolarHBondContact O-N 3.3Å
146	T	90.6	Very high	87.9	Confident	53 Å²	53	84.6 Å²	84.6	33%	0.325	41%	0.412	S	S	.	.			trans	-89.1	156	174.5	68.6	0	0	0	0	111.4	I144 R148 R149 A150	I144-T146 PolarHBondContact O-N 3.49Å; T146-R148 PolarHBondContact O-N 2.9Å; T146-R149 PolarHBondContact O-N 2.87Å; T146-R149 VanDerWaalsContact O-N 3.15Å; T146-R149 WeakPolarHBondContact OG1-CG 3.3Å; T146-R149 PolarHBondContact OG1-N 2.93Å; T146-A150 PolarHBondContact O-N 2.73Å
147	K	88.4	Confident	88.6	Confident	139 Å²	139	83.5 Å²	83.5	60%	0.604	40%	0.404	S	S	*	.	H	α-helix	trans	-55.5	-38.9	177.2	-64.2	-179	-177.4	176.6	0	112.9	A150 L151	K147-A150 PolarHBondContact O-N 3.27Å; K147-L151 WeakPolarHBondContact O-CG 3.48Å; K147-L151 PolarHBondContact O-N 2.82Å
148	R	90.7	Very high	89.2	Confident	219 Å²	219	80.6 Å²	80.6	83%	0.826	39%	0.392	S	S	*	.	H	α-helix	trans	-63.4	-44.6	178.5	-69	-175.8	-178.7	173.4	0	111.7	T146 L151 L152	T146-R148 PolarHBondContact O-N 2.9Å; R148-L151 PolarHBondContact O-N 3.19Å; R148-L152 WeakPolarHBondContact O-CB 3.37Å; R148-L152 PolarHBondContact O-N 3.19Å
149	R	92.3	Very high	90.1	Very high	147 Å²	147	82.7 Å²	82.7	56%	0.555	40%	0.404	S	S	*	.	H	α-helix	trans	-65.6	-39.8	177.2	-71.9	177.9	177.2	-179.8	-4.1	111.9	I144 T146 L152 A153	I144-R149 VanDerWaalsContact O-CD 3.32Å; I144-R149 WeakPolarHBondContact O-CD 3.29Å; I144-R149 PolarHBondContact O-NH1 3.16Å; T146-R149 PolarHBondContact O-N 2.87Å; T146-R149 VanDerWaalsContact O-N 3.15Å; T146-R149 WeakPolarHBondContact OG1-CG 3.3Å; T146-R149 PolarHBondContact OG1-N 2.93Å; R149-L152 PolarHBondContact O-N 3.38Å; R149-A153 WeakPolarHBondContact O-CB 3.15Å; R149-A153 PolarHBondContact O-N 3.19Å
150	A	91.3	Very high	90.9	Very high	6 Å²	6	82.5 Å²	82.5	5%	0.05	40%	0.403	C	S	.	.	H	α-helix	trans	-63.9	-45.6	175.8	0	0	0	0	0	112.3	V67 F71 T146 K147 L152 A153 V154	V67-A150 HydrophobicContact CG1-CB 3.55Å; F71-A150 HydrophobicContact CE1-CB 4.03Å; F71-A150 HydrophobicContact CE2-CB 4.4Å; F71-A150 HydrophobicContact CZ-CB 3.64Å; T146-A150 PolarHBondContact O-N 2.73Å; K147-A150 PolarHBondContact O-N 3.27Å; A150-L152 PolarHBondContact O-N 3.46Å; A150-A153 PolarHBondContact O-N 3.48Å; A150-V154 WeakPolarHBondContact O-CG2 3.27Å; A150-V154 PolarHBondContact O-N 3.11Å
151	L	91.3	Very high	91.5	Very high	112 Å²	112	74.2 Å²	74.2	59%	0.586	37%	0.372	S	S	*	.	H	α-helix	trans	-61.9	-42.6	174.5	-72	172	0	0	0	111.7	K147 R148 A153 V154 M155	K147-L151 WeakPolarHBondContact O-CG 3.48Å; K147-L151 PolarHBondContact O-N 2.82Å; R148-L151 PolarHBondContact O-N 3.19Å; L151-A153 PolarHBondContact O-N 3.24Å; L151-V154 PolarHBondContact O-N 3.35Å; L151-M155 WeakPolarHBondContact O-CG 3.33Å; L151-M155 PolarHBondContact O-N 3.16Å
152	L	94.1	Very high	92	Very high	108 Å²	108	76.1 Å²	76.1	57%	0.565	38%	0.384	S	S	*	.	H	α-helix	trans	-62.2	-41.7	176	-177.6	145.8	0	0	0	111.8	R148 R149 A150 V154 M155 L156	R148-L152 WeakPolarHBondContact O-CB 3.37Å; R148-L152 PolarHBondContact O-N 3.19Å; R149-L152 PolarHBondContact O-N 3.38Å; A150-L152 PolarHBondContact O-N 3.46Å; L152-V154 VanDerWaalsContact C-N 3.31Å; L152-V154 PolarHBondContact O-N 2.89Å; L152-M155 PolarHBondContact O-N 3.35Å; L152-L156 HydrophobicContact CD2-CD1 3.53Å; L152-L156 HydrophobicContact CD2-CG 4.15Å; L152-L156 HydrophobicContact CG-CD1 4.45Å; L152-L156 WeakPolarHBondContact O-CG 3.35Å; L152-L156 PolarHBondContact O-N 3.05Å
153	A	93.7	Very high	92.5	Very high	28 Å²	28	76.1 Å²	76.1	23%	0.231	38%	0.378	C	S	.	.	H	α-helix	trans	-61.3	-40.1	174.4	0	0	0	0	0	111.9	F71 V126 R149 A150 L151 L156 L157	F71-A153 HydrophobicContact CE1-CB 4.44Å; V126-A153 HydrophobicContact CG1-CB 4.42Å; R149-A153 WeakPolarHBondContact O-CB 3.15Å; R149-A153 PolarHBondContact O-N 3.19Å; A150-A153 PolarHBondContact O-N 3.48Å; L151-A153 PolarHBondContact O-N 3.24Å; A153-L156 PolarHBondContact O-N 3.17Å; A153-L157 PolarHBondContact O-N 3.4Å
154	V	94.7	Very high	92.8	Very high	23 Å²	23	72.9 Å²	72.9	14%	0.139	35%	0.354	C	S	.	.	H	α-helix	trans	-65.5	-42.3	173.2	174.8	0	0	0	0	111.8	F71 N74 A150 L151 L152 L156 L157 W158	F71-V154 HydrophobicContact CD1-CG2 3.93Å; F71-V154 HydrophobicContact CE1-CG2 3.97Å; N74-V154 HydrophobicContact CB-CG2 4.4Å; N74-V154 WeakPolarHBondContact OD1-CG1 3.48Å; A150-V154 WeakPolarHBondContact O-CG2 3.27Å; A150-V154 PolarHBondContact O-N 3.11Å; L151-V154 PolarHBondContact O-N 3.35Å; L152-V154 VanDerWaalsContact C-N 3.31Å; L152-V154 PolarHBondContact O-N 2.89Å; V154-L156 PolarHBondContact O-N 3.4Å; V154-L157 HydrophobicContact CB-CD2 4.29Å; V154-L157 HydrophobicContact CG1-CD2 4.49Å; V154-L157 HydrophobicContact CG2-CD2 4.2Å; V154-L157 VanDerWaalsContact O-CG 3.3Å; V154-L157 WeakPolarHBondContact O-CG 3.27Å; V154-L157 PolarHBondContact O-N 2.76Å; V154-W158 PolarHBondContact O-N 3.02Å
155	M	95.1	Very high	93	Very high	124 Å²	124	70.8 Å²	70.8	61%	0.611	34%	0.344	S	S	*	.	H	α-helix	trans	-62.6	-44.7	176.2	-69.2	-59.4	-59.9	0	0	111.7	L151 L152 L157 W158 V159	L151-M155 WeakPolarHBondContact O-CG 3.33Å; L151-M155 PolarHBondContact O-N 3.16Å; L152-M155 PolarHBondContact O-N 3.35Å; M155-L157 PolarHBondContact O-N 2.94Å; M155-W158 PolarHBondContact O-N 3.3Å; M155-V159 WeakPolarHBondContact O-CG2 3.4Å; M155-V159 PolarHBondContact O-N 2.68Å
156	L	94.6	Very high	93	Very high	97 Å²	97	72 Å²	72	51%	0.508	35%	0.35	S	S	.	.	H	α-helix	trans	-62.6	-40.6	178.4	-71.6	177.6	0	0	0	112.3	L152 A153 V154 W158 V159 L160	L152-L156 HydrophobicContact CD2-CD1 3.53Å; L152-L156 HydrophobicContact CD2-CG 4.15Å; L152-L156 HydrophobicContact CG-CD1 4.45Å; L152-L156 WeakPolarHBondContact O-CG 3.35Å; L152-L156 PolarHBondContact O-N 3.05Å; A153-L156 PolarHBondContact O-N 3.17Å; V154-L156 PolarHBondContact O-N 3.4Å; L156-W158 PolarHBondContact O-N 3.44Å; L156-V159 PolarHBondContact O-N 3.01Å; L156-L160 WeakPolarHBondContact O-CB 3.43Å; L156-L160 VanDerWaalsContact O-CG 3.28Å; L156-L160 WeakPolarHBondContact O-CG 3.37Å; L156-L160 PolarHBondContact O-N 3.35Å
157	L	95.1	Very high	92.8	Very high	3 Å²	3	69.9 Å²	69.9	2%	0.016	34%	0.339	C	S	.	.	H	α-helix	trans	-65.3	-40.2	179.6	80.9	88.2	0	0	0	111.9	A119 M122 V126 A153 V154 M155 L160 S161	A119-L157 HydrophobicContact CB-CD1 4.35Å; M122-L157 HydrophobicContact CB-CB 4.15Å; V126-L157 HydrophobicContact CG2-CD2 4.46Å; A153-L157 PolarHBondContact O-N 3.4Å; V154-L157 HydrophobicContact CB-CD2 4.29Å; V154-L157 HydrophobicContact CG1-CD2 4.49Å; V154-L157 HydrophobicContact CG2-CD2 4.2Å; V154-L157 VanDerWaalsContact O-CG 3.3Å; V154-L157 WeakPolarHBondContact O-CG 3.27Å; V154-L157 PolarHBondContact O-N 2.76Å; M155-L157 PolarHBondContact O-N 2.94Å; L157-L160 PolarHBondContact O-N 3.15Å; L157-S161 WeakPolarHBondContact O-CB 3.41Å; L157-S161 PolarHBondContact O-N 3.3Å; L157-S161 PolarHBondContact O-OG 2.89Å
158	W	96.3	Very high	92.6	Very high	52 Å²	52	64.5 Å²	64.5	20%	0.197	32%	0.318	C	S	.	.	H	α-helix	trans	-65.9	-43.4	176.5	-80.1	106.9	0	0	0	111.3	N74 V77 A78 L81 L115 A119 V154 M155 L156 L160 S161 I162	N74-W158 PolarHBondContact OD1-NE1 3.26Å; V77-W158 HydrophobicContact CG1-CZ2 4.5Å; A78-W158 HydrophobicContact CB-CH2 4.36Å; A78-W158 HydrophobicContact CB-CZ2 4.45Å; L81-W158 HydrophobicContact CD2-CH2 4.46Å; L115-W158 HydrophobicContact CD1-CE3 4.42Å; L115-W158 HydrophobicContact CG-CZ3 4.5Å; A119-W158 HydrophobicContact CB-CE3 4.24Å; A119-W158 HydrophobicContact CB-CH2 4.15Å; A119-W158 HydrophobicContact CB-CZ3 4.01Å; V154-W158 PolarHBondContact O-N 3.02Å; M155-W158 PolarHBondContact O-N 3.3Å; L156-W158 PolarHBondContact O-N 3.44Å; W158-L160 PolarHBondContact O-N 3.5Å; W158-S161 PolarHBondContact O-N 3.06Å; W158-I162 VanDerWaalsContact O-CG1 3.28Å; W158-I162 WeakPolarHBondContact O-CG1 3.22Å; W158-I162 PolarHBondContact O-N 3.28Å
159	V	95.9	Very high	92.2	Very high	72 Å²	72	58.5 Å²	58.5	44%	0.436	30%	0.302	S	S	.	.	H	α-helix	trans	-59.8	-47.7	175.9	170.1	0	0	0	0	111.2	M155 L156 S161 I162 I163	M155-V159 WeakPolarHBondContact O-CG2 3.4Å; M155-V159 PolarHBondContact O-N 2.68Å; L156-V159 PolarHBondContact O-N 3.01Å; V159-S161 VanDerWaalsContact C-N 3.29Å; V159-S161 PolarHBondContact O-N 2.79Å; V159-I162 PolarHBondContact O-N 3.29Å; V159-I163 HydrophobicContact CG1-CD1 3.82Å; V159-I163 VanDerWaalsContact O-CG1 3.29Å; V159-I163 WeakPolarHBondContact O-CG1 3.42Å; V159-I163 PolarHBondContact O-N 2.9Å
160	L	94	Very high	91.8	Very high	82 Å²	82	59.7 Å²	59.7	43%	0.429	31%	0.312	S	S	.	.	H	α-helix	trans	-61.9	-38.7	177.6	-71.4	171.5	0	0	0	112	M122 L156 L157 W158 I163 I164	M122-L160 HydrophobicContact CE-CD1 3.94Å; L156-L160 WeakPolarHBondContact O-CB 3.43Å; L156-L160 VanDerWaalsContact O-CG 3.28Å; L156-L160 WeakPolarHBondContact O-CG 3.37Å; L156-L160 PolarHBondContact O-N 3.35Å; L157-L160 PolarHBondContact O-N 3.15Å; W158-L160 PolarHBondContact O-N 3.5Å; L160-I163 PolarHBondContact O-N 3.27Å; L160-I164 WeakPolarHBondContact O-CG1 3.45Å; L160-I164 PolarHBondContact O-N 3.43Å; L160-I164 VanDerWaalsContact O-N 3.11Å
161	S	95.7	Very high	91.1	Very high	0 Å²	0	62.2 Å²	62.2	0%	0	34%	0.338	C	S	.	.	H	α-helix	trans	-68.4	-39.3	179.2	-54.5	0	0	0	0	111.4	A119 L157 W158 V159 I164 S165	A119-S161 WeakPolarHBondContact CA-OG 3.41Å; A119-S161 PolarHBondContact N-OG 2.89Å; L157-S161 WeakPolarHBondContact O-CB 3.41Å; L157-S161 PolarHBondContact O-N 3.3Å; L157-S161 PolarHBondContact O-OG 2.89Å; W158-S161 PolarHBondContact O-N 3.06Å; V159-S161 VanDerWaalsContact C-N 3.29Å; V159-S161 PolarHBondContact O-N 2.79Å; S161-I164 PolarHBondContact O-N 3.38Å; S161-S165 WeakPolarHBondContact O-CB 3.36Å; S161-S165 PolarHBondContact O-N 3.07Å; S161-S165 PolarHBondContact O-OG 3.09Å
162	I	94.4	Very high	90.5	Very high	78 Å²	78	64.2 Å²	64.2	40%	0.4	34%	0.338	S	S	.	.	H	α-helix	trans	-62.1	-48.9	173.5	-69.2	166.4	0	0	0	110.4	L115 W158 V159 I164 S165 I166	L115-I162 HydrophobicContact CD1-CB 4.39Å; L115-I162 HydrophobicContact CD1-CG1 3.62Å; W158-I162 VanDerWaalsContact O-CG1 3.28Å; W158-I162 WeakPolarHBondContact O-CG1 3.22Å; W158-I162 PolarHBondContact O-N 3.28Å; V159-I162 PolarHBondContact O-N 3.29Å; I162-I164 PolarHBondContact O-N 3.38Å; I162-S165 WeakPolarHBondContact CA-OG 3.49Å; I162-S165 PolarHBondContact O-N 2.97Å; I162-S165 PolarHBondContact O-OG 2.96Å; I162-I166 HydrophobicContact CG2-CG2 4.08Å; I162-I166 WeakPolarHBondContact O-CG1 3.38Å; I162-I166 WeakPolarHBondContact O-CG2 3.4Å; I162-I166 PolarHBondContact O-N 2.64Å
163	I	92.6	Very high	89.5	Confident	91 Å²	91	61.7 Å²	61.7	47%	0.467	32%	0.322	S	S	.	.	H	α-helix	trans	-56	-41	179.6	-70.2	165.6	0	0	0	111.4	V159 L160 I166	V159-I163 HydrophobicContact CG1-CD1 3.82Å; V159-I163 VanDerWaalsContact O-CG1 3.29Å; V159-I163 WeakPolarHBondContact O-CG1 3.42Å; V159-I163 PolarHBondContact O-N 2.9Å; L160-I163 PolarHBondContact O-N 3.27Å; I163-I166 WeakPolarHBondContact O-CG1 3.4Å
164	I	91.6	Very high	88.4	Confident	16 Å²	16	64.5 Å²	64.5	8%	0.082	33%	0.331	C	S	.	.	H	α-helix	trans	-70.7	-41.1	177.9	-64.8	164.4	0	0	0	111	V114 T118 L160 S161 I162 I166 Y191 F194 S199	V114-I164 HydrophobicContact CG1-CG2 4.32Å; T118-I164 HydrophobicContact CG2-CD1 3.89Å; L160-I164 WeakPolarHBondContact O-CG1 3.45Å; L160-I164 PolarHBondContact O-N 3.43Å; L160-I164 VanDerWaalsContact O-N 3.11Å; S161-I164 PolarHBondContact O-N 3.38Å; I162-I164 PolarHBondContact O-N 3.38Å; I164-I166 PolarHBondContact O-N 2.89Å; I164-Y191 PolarHBondContact O-OH 3.11Å; I164-F194 HydrophobicContact CG1-CE1 4.34Å; I164-F194 HydrophobicContact CG1-CZ 4.5Å; I164-F194 HydrophobicContact CG2-CE1 4.47Å; I164-S199 WeakPolarHBondContact CG2-OG 3.4Å
165	S	91.7	Very high	87.1	Confident	5 Å²	5	69.1 Å²	69.1	4%	0.035	36%	0.361	C	S	.	.	H	α-helix	trans	-71.1	-28.3	-175	68.6	0	0	0	0	115.7	A111 S161 I162 G167 P168	A111-S165 WeakPolarHBondContact O-CB 3.29Å; S161-S165 WeakPolarHBondContact O-CB 3.36Å; S161-S165 PolarHBondContact O-N 3.07Å; S161-S165 PolarHBondContact O-OG 3.09Å; I162-S165 WeakPolarHBondContact CA-OG 3.49Å; I162-S165 PolarHBondContact O-N 2.97Å; I162-S165 PolarHBondContact O-OG 2.96Å; S165-G167 VanDerWaalsContact C-N 3.34Å; S165-G167 PolarHBondContact O-N 2.95Å; S165-P168 WeakPolarHBondContact O-CD 3.48Å
166	I	89.4	Confident	85.5	Confident	56 Å²	56	65.4 Å²	65.4	29%	0.287	35%	0.35	S	S	.	.	T	Hydrogen-bonded Turn	trans	-80.8	-11.5	-174.5	61.1	-171.5	0	0	0	113.6	I162 I163 I164 L169 F170	I162-I166 HydrophobicContact CG2-CG2 4.08Å; I162-I166 WeakPolarHBondContact O-CG1 3.38Å; I162-I166 WeakPolarHBondContact O-CG2 3.4Å; I162-I166 PolarHBondContact O-N 2.64Å; I163-I166 WeakPolarHBondContact O-CG1 3.4Å; I164-I166 PolarHBondContact O-N 2.89Å; I166-L169 HydrophobicContact CG2-CD1 4.48Å; I166-L169 WeakPolarHBondContact O-CB 3.47Å; I166-L169 PolarHBondContact O-N 3.36Å; I166-F170 HydrophobicContact CB-CD2 4.38Å; I166-F170 HydrophobicContact CB-CE2 4.04Å; I166-F170 HydrophobicContact CD1-CE2 3.9Å; I166-F170 HydrophobicContact CG1-CD2 4.32Å; I166-F170 HydrophobicContact CG1-CE2 3.93Å; I166-F170 WeakPolarHBondContact O-CD2 3.27Å
167	G	86	Confident	84.1	Confident	9 Å²	9	63.8 Å²	63.8	9%	0.093	35%	0.346	C	S	.	.	G	3₁₀ helix	trans	-45.9	-50.5	-177.7	0	0	0	0	0	114.4	S165 L169 F170	S165-G167 VanDerWaalsContact C-N 3.34Å; S165-G167 PolarHBondContact O-N 2.95Å; G167-L169 PolarHBondContact O-N 2.87Å; G167-F170 PolarHBondContact O-N 3.4Å
168	P	84.3	Confident	82.4	Confident	26 Å²	26	73.1 Å²	73.1	17%	0.169	39%	0.389	C	S	.	.	G	3₁₀ helix	trans	-66.4	-23.4	-179.1	-23.3	37.6	0	0	0	113.9	S165 F170 G171 K173 Y191	S165-P168 WeakPolarHBondContact O-CD 3.48Å; P168-F170 VanDerWaalsContact C-N 3.3Å; P168-G171 PolarHBondContact O-N 3.33Å; P168-K173 HydrophobicContact CB-CB 4.4Å; P168-Y191 VanDerWaalsContact CD-CE2 3.43Å; P168-Y191 WeakPolarHBondContact CD-OH 3.09Å; P168-Y191 HydrophobicContact CG-CD1 3.91Å; P168-Y191 HydrophobicContact CG-CD2 4.19Å; P168-Y191 HydrophobicContact CG-CE1 3.4Å; P168-Y191 HydrophobicContact CG-CE2 3.73Å; P168-Y191 HydrophobicContact CG-CG 4.27Å
169	L	83.1	Confident	81	Confident	94 Å²	94	75.4 Å²	75.4	49%	0.492	41%	0.405	S	S	.	.	G	3₁₀ helix	trans	-74	-22.7	178.8	-59.5	177.6	0	0	0	112.4	N107 A111 I166 G167 G171	N107-L169 HydrophobicContact CB-CD2 4.01Å; A111-L169 HydrophobicContact CB-CD1 4.33Å; I166-L169 HydrophobicContact CG2-CD1 4.48Å; I166-L169 WeakPolarHBondContact O-CB 3.47Å; I166-L169 PolarHBondContact O-N 3.36Å; G167-L169 PolarHBondContact O-N 2.87Å; L169-G171 VanDerWaalsContact C-N 3.31Å
170	F	83.6	Confident	79.8	Confident	172 Å²	172	77.9 Å²	77.9	75%	0.754	41%	0.412	S	S	*	.	G	3₁₀ helix	trans	-90.1	9.4	175.7	-71.2	-76.5	0	0	0	113.6	I166 G167 P168	I166-F170 HydrophobicContact CB-CD2 4.38Å; I166-F170 HydrophobicContact CB-CE2 4.04Å; I166-F170 HydrophobicContact CD1-CE2 3.9Å; I166-F170 HydrophobicContact CG1-CD2 4.32Å; I166-F170 HydrophobicContact CG1-CE2 3.93Å; I166-F170 WeakPolarHBondContact O-CD2 3.27Å; G167-F170 PolarHBondContact O-N 3.4Å; P168-F170 VanDerWaalsContact C-N 3.3Å
171	G	75.2	Confident	78.7	Confident	58 Å²	58	76.5 Å²	76.5	60%	0.598	41%	0.409	S	S	*	.	T	Hydrogen-bonded Turn	trans	94.4	9	177.5	0	0	0	0	0	115.1	P168 L169 K173	P168-G171 PolarHBondContact O-N 3.33Å; L169-G171 VanDerWaalsContact C-N 3.31Å; G171-K173 PolarHBondContact O-N 3.27Å
172	W	78.6	Confident	77.9	Confident	154 Å²	154	80 Å²	80	58%	0.583	43%	0.427	S	S	*	.			trans	-78	62.8	163	-90.1	-12	0	0	0	110.7	Y191 F194	W172-Y191 HydrophobicContact CE3-CD2 4.4Å; W172-F194 HydrophobicContact CZ3-CD1 4.42Å
173	K	74.4	Confident	77.3	Confident	56 Å²	56	76.4 Å²	76.4	24%	0.243	41%	0.409	C	S	.	.	S	Bend	trans	-149.5	147.8	178.5	179.7	171.6	176.1	168.2	0	110	N107 P168 G171 T186	N107-K173 PolarHBondContact OD1-NZ 3.43Å; P168-K173 HydrophobicContact CB-CB 4.4Å; G171-K173 PolarHBondContact O-N 3.27Å; K173-T186 HydrophobicContact CB-CG2 4.01Å; K173-T186 WeakPolarHBondContact CD-OG1 3.47Å; K173-T186 HydrophobicContact CG-CG2 3.98Å; K173-T186 WeakPolarHBondContact CG-OG1 3.28Å
174	E	69.7	Low	76.4	Confident	87 Å²	87	77.5 Å²	77.5	41%	0.407	41%	0.41	S	S	.	.	P	Polyproline II helix	trans	-52.6	150.5	172.2	-82.6	158.1	-135.2	0	0	111.3	A176 E187 E188	E174-A176 PolarHBondContact O-N 3.46Å; E174-E187 VanDerWaalsContact OE1-C 3.23Å; E174-E188 HydrophobicContact CB-CG 4.44Å; E174-E188 HydrophobicContact CG-CG 3.85Å; E174-E188 WeakPolarHBondContact CG-OE1 3.41Å; E174-E188 VanDerWaalsContact N-CG 3.32Å; E174-E188 PolarHBondContact OE1-N 3.09Å; E174-E188 VanDerWaalsContact OE1-N 3.13Å
175	P	67.5	Low	75.8	Confident	119 Å²	119	77.9 Å²	77.9	77%	0.773	41%	0.412	S	S	*	.	P	Polyproline II helix	trans	-55.3	128	170.6	24.5	-32.5	0	0	0	109.2
176	A	62.3	Low	75.1	Confident	46 Å²	46	78 Å²	78	38%	0.38	41%	0.413	S	S	.	.	P	Polyproline II helix	trans	-66.5	135.6	-169.9	0	0	0	0	0	111.1	E174	E174-A176 PolarHBondContact O-N 3.46Å
177	P	64.7	Low	74.3	Confident	64 Å²	64	76.7 Å²	76.7	42%	0.416	41%	0.405	S	S	.	.	P	Polyproline II helix	trans	-59.4	151.1	-177.1	23.1	-32.6	0	0	0	111.4	R103 D179	R103-P177 PolarHBondContact NH2-O 3.39Å; P177-D179 PolarHBondContact O-N 3.02Å
178	E	60.1	Low	74.1	Confident	198 Å²	198	79.4 Å²	79.4	93%	0.925	42%	0.416	S	S	*	.	S	Bend	trans	-60.2	-29.1	179.9	-64.5	-175.6	173.3	0	0	112.1
179	D	67.4	Low	74	Confident	100 Å²	100	80.8 Å²	80.8	54%	0.535	43%	0.425	S	S	.	.			trans	-86.3	116.8	177.4	-66	-37	0	0	0	112.8	P177 S181 I182	P177-D179 PolarHBondContact O-N 3.02Å; D179-S181 PolarHBondContact O-N 2.94Å; D179-I182 HydrophobicContact CB-CD1 4.25Å; D179-I182 HydrophobicContact CB-CG1 4.39Å
180	E	69.8	Low	74.1	Confident	124 Å²	124	78.8 Å²	78.8	58%	0.579	43%	0.427	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.1	-10.6	174.3	-61.4	-163.8	155.1	0	0	114	I182	E180-I182 VanDerWaalsContact C-N 3.28Å; E180-I182 PolarHBondContact O-N 2.61Å
181	S	71.1	Confident	74.2	Confident	54 Å²	54	70.9 Å²	70.9	38%	0.378	39%	0.392	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79	-5.7	178.9	53.9	0	0	0	0	114.1	W99 D179	W99-S181 WeakPolarHBondContact CB-O 3.29Å; W99-S181 PolarHBondContact N-O 2.66Å; D179-S181 PolarHBondContact O-N 2.94Å
182	I	78.5	Confident	74.8	Confident	73 Å²	73	68.2 Å²	68.2	37%	0.374	36%	0.364	S	S	.	.			trans	-109.3	113.2	-179.3	-57.6	175.1	0	0	0	109.1	D179 E180 K184	D179-I182 HydrophobicContact CB-CD1 4.25Å; D179-I182 HydrophobicContact CB-CG1 4.39Å; E180-I182 VanDerWaalsContact C-N 3.28Å; E180-I182 PolarHBondContact O-N 2.61Å; I182-K184 HydrophobicContact CG2-CD 4.19Å; I182-K184 HydrophobicContact CG2-CG 3.94Å
183	C	81.6	Confident	75.2	Confident	3 Å²	3	64.4 Å²	64.4	2%	0.02	35%	0.354	C	S	.	.			trans	-111.5	105	171.5	-177.4	0	0	0	0	109.5	W99 C106 W109	W99-C183 HydrophobicContact CB-CB 3.78Å; W99-C183 HydrophobicContact CD2-CB 3.51Å; W99-C183 HydrophobicContact CE3-CB 3.79Å; W99-C183 HydrophobicContact CG-CB 3.53Å; C106-C183 VanDerWaalsContact CA-SG 3.56Å; C106-C183 HydrophobicContact CB-CB 3.87Å; C106-C183 WeakPolarHBondContact CB-SG 2.97Å; C106-C183 WeakPolarHBondContact SG-CA 3.29Å; C106-C183 WeakPolarHBondContact SG-CB 3.33Å; C106-C183 CovalentContact SG-SG 2.03Å; C106-C183 PolarHBondContact SG-SG 3.06Å; W109-C183 VanDerWaalsContact CE3-SG 3.59Å
184	K	74.4	Confident	76	Confident	113 Å²	113	66 Å²	66	49%	0.491	36%	0.362	S	S	.	.			trans	-113.3	144.8	173.5	-67.9	-178	-179.8	-176.6	0	110.1	I182	I182-K184 HydrophobicContact CG2-CD 4.19Å; I182-K184 HydrophobicContact CG2-CG 3.94Å
185	I	77.9	Confident	76.9	Confident	24 Å²	24	62.4 Å²	62.4	12%	0.123	35%	0.346	C	S	.	.			trans	-61.2	141.4	166.8	-62.9	169.8	0	0	0	107.2	W109 E187 F317	W109-I185 HydrophobicContact CH2-CG1 4.36Å; W109-I185 HydrophobicContact CZ3-CG1 4.27Å; I185-E187 PolarHBondContact O-N 3.5Å; I185-F317 HydrophobicContact CD1-CD2 4.48Å; I185-F317 HydrophobicContact CD1-CE2 3.47Å; I185-F317 VanDerWaalsContact CD1-CE2 3.47Å; I185-F317 HydrophobicContact CD1-CZ 3.82Å
186	T	77.3	Confident	78	Confident	8 Å²	8	56.8 Å²	56.8	5%	0.049	31%	0.31	C	S	.	.			trans	-57.2	118.8	-179.2	-59	0	0	0	0	111.3	K173 E188 Y191	K173-T186 HydrophobicContact CB-CG2 4.01Å; K173-T186 WeakPolarHBondContact CD-OG1 3.47Å; K173-T186 HydrophobicContact CG-CG2 3.98Å; K173-T186 WeakPolarHBondContact CG-OG1 3.28Å; T186-E188 HydrophobicContact CG2-CB 3.73Å; T186-E188 HydrophobicContact CG2-CG 4.03Å; T186-Y191 HydrophobicContact CG2-CD1 3.99Å
187	E	72.5	Confident	79.4	Confident	28 Å²	28	58 Å²	58	13%	0.131	31%	0.312	C	S	.	.			trans	-96.3	4.5	177	-70.9	177.4	-159.9	0	0	112.8	E174 I185 S301 R307	E174-E187 VanDerWaalsContact OE1-C 3.23Å; I185-E187 PolarHBondContact O-N 3.5Å; E187-S301 WeakPolarHBondContact O-CB 3.29Å; E187-S301 PolarHBondContact O-OG 3.06Å; E187-R307 IonicContact OE1-CZ 3.28Å; E187-R307 IonicContact OE1-NH1 2.77Å; E187-R307 IonicContact OE1-NH2 3.09Å; E187-R307 PolarHBondContact OE1-NH2 3.34Å; E187-R307 IonicContact OE2-CZ 2.8Å; E187-R307 VanDerWaalsContact OE2-CZ 3.28Å; E187-R307 IonicContact OE2-NH1 3.66Å; E187-R307 PolarHBondContact OE2-NH1 3.4Å; E187-R307 IonicContact OE2-NH2 3.16Å; E187-R307 PolarHBondContact OE2-NH2 3.3Å; E187-R307 VanDerWaalsContact OE2-NH2 3.11Å
188	E	82.4	Confident	80.6	Confident	66 Å²	66	55.8 Å²	55.8	31%	0.308	30%	0.301	S	S	.	.			trans	-48.3	123.9	175.2	-88.6	-63.8	146.9	0	0	111	E174 T186 G190 Y191 A192	E174-E188 HydrophobicContact CB-CG 4.44Å; E174-E188 HydrophobicContact CG-CG 3.85Å; E174-E188 WeakPolarHBondContact CG-OE1 3.41Å; E174-E188 VanDerWaalsContact N-CG 3.32Å; E174-E188 PolarHBondContact OE1-N 3.09Å; E174-E188 VanDerWaalsContact OE1-N 3.13Å; T186-E188 HydrophobicContact CG2-CB 3.73Å; T186-E188 HydrophobicContact CG2-CG 4.03Å; E188-G190 VanDerWaalsContact C-N 3.3Å; E188-G190 PolarHBondContact O-N 3.26Å; E188-Y191 PolarHBondContact O-N 3Å; E188-Y191 VanDerWaalsContact O-N 3.15Å; E188-A192 VanDerWaalsContact O-CB 3.27Å; E188-A192 WeakPolarHBondContact O-CB 3.29Å; E188-A192 PolarHBondContact O-N 3.41Å
189	P	81.2	Confident	82	Confident	56 Å²	56	46.6 Å²	46.6	36%	0.364	26%	0.259	S	S	.	.	H	α-helix	trans	-59.7	-37.8	-172.1	21.5	-33.2	0	0	0	113.6	I193 S301	P189-I193 WeakPolarHBondContact O-CB 3.31Å; P189-I193 WeakPolarHBondContact O-CD1 3.32Å; P189-I193 WeakPolarHBondContact O-CG1 3.5Å; P189-I193 PolarHBondContact O-N 2.94Å; P189-I193 VanDerWaalsContact O-N 3.08Å; P189-S301 WeakPolarHBondContact CA-OG 3.49Å
190	G	85.6	Confident	83.1	Confident	52 Å²	52	41.8 Å²	41.8	54%	0.536	23%	0.233	S	C	.	.	H	α-helix	trans	-62.6	-48	177.5	0	0	0	0	0	112.5	E188 F194	E188-G190 VanDerWaalsContact C-N 3.3Å; E188-G190 PolarHBondContact O-N 3.26Å; G190-F194 VanDerWaalsContact O-CB 3.3Å; G190-F194 WeakPolarHBondContact O-CB 3.48Å; G190-F194 PolarHBondContact O-N 3.42Å; G190-F194 VanDerWaalsContact O-N 3.11Å
191	Y	86.8	Confident	84.2	Confident	6 Å²	6	39.5 Å²	39.5	2%	0.024	22%	0.22	C	C	.	.	H	α-helix	trans	-74.3	-40.5	-179.6	176.9	-103.6	0	0	0	112.6	I164 P168 W172 T186 E188 I193 F194 S195	I164-Y191 PolarHBondContact O-OH 3.11Å; P168-Y191 VanDerWaalsContact CD-CE2 3.43Å; P168-Y191 WeakPolarHBondContact CD-OH 3.09Å; P168-Y191 HydrophobicContact CG-CD1 3.91Å; P168-Y191 HydrophobicContact CG-CD2 4.19Å; P168-Y191 HydrophobicContact CG-CE1 3.4Å; P168-Y191 HydrophobicContact CG-CE2 3.73Å; P168-Y191 HydrophobicContact CG-CG 4.27Å; W172-Y191 HydrophobicContact CE3-CD2 4.4Å; T186-Y191 HydrophobicContact CG2-CD1 3.99Å; E188-Y191 PolarHBondContact O-N 3Å; E188-Y191 VanDerWaalsContact O-N 3.15Å; Y191-I193 VanDerWaalsContact C-N 3.33Å; Y191-I193 PolarHBondContact O-N 3.41Å; Y191-F194 PolarHBondContact O-N 2.91Å; Y191-S195 VanDerWaalsContact O-CB 3.27Å; Y191-S195 WeakPolarHBondContact O-CB 3.49Å; Y191-S195 PolarHBondContact O-N 3.21Å; Y191-S195 PolarHBondContact O-OG 3.46Å
192	A	86.3	Confident	85.2	Confident	1 Å²	1	41.8 Å²	41.8	1%	0.008	23%	0.227	C	C	.	.	H	α-helix	trans	-59.6	-43.6	178	0	0	0	0	0	111.3	E188 S195 A196	E188-A192 VanDerWaalsContact O-CB 3.27Å; E188-A192 WeakPolarHBondContact O-CB 3.29Å; E188-A192 PolarHBondContact O-N 3.41Å; A192-S195 PolarHBondContact O-OG 2.99Å; A192-A196 WeakPolarHBondContact O-CB 3.11Å; A192-A196 PolarHBondContact O-N 3.13Å
193	I	88.5	Confident	85.9	Confident	74 Å²	74	38.4 Å²	38.4	38%	0.379	21%	0.21	S	C	.	.	H	α-helix	trans	-68.7	-48.7	176.5	-64.9	167.2	0	0	0	110.6	P189 Y191 S195 A196 V197 I302	P189-I193 WeakPolarHBondContact O-CB 3.31Å; P189-I193 WeakPolarHBondContact O-CD1 3.32Å; P189-I193 WeakPolarHBondContact O-CG1 3.5Å; P189-I193 PolarHBondContact O-N 2.94Å; P189-I193 VanDerWaalsContact O-N 3.08Å; Y191-I193 VanDerWaalsContact C-N 3.33Å; Y191-I193 PolarHBondContact O-N 3.41Å; I193-S195 PolarHBondContact O-N 3.36Å; I193-A196 PolarHBondContact O-N 3.4Å; I193-V197 HydrophobicContact CG2-CG2 4.17Å; I193-V197 WeakPolarHBondContact O-CB 3.21Å; I193-V197 VanDerWaalsContact O-CG2 3.26Å; I193-V197 WeakPolarHBondContact O-CG2 3.4Å; I193-V197 PolarHBondContact O-N 3.22Å; I193-I302 HydrophobicContact CD1-CD1 3.89Å; I193-I302 HydrophobicContact CD1-CG1 4.12Å; I193-I302 HydrophobicContact CG1-CD1 4.19Å
194	F	90.1	Very high	86.4	Confident	90 Å²	90	39 Å²	39	40%	0.395	21%	0.213	S	C	.	.	H	α-helix	trans	-57.3	-49.3	179.9	171.7	-101.2	0	0	0	112	I164 W172 G190 Y191 V197 G198	I164-F194 HydrophobicContact CG1-CE1 4.34Å; I164-F194 HydrophobicContact CG1-CZ 4.5Å; I164-F194 HydrophobicContact CG2-CE1 4.47Å; W172-F194 HydrophobicContact CZ3-CD1 4.42Å; G190-F194 VanDerWaalsContact O-CB 3.3Å; G190-F194 WeakPolarHBondContact O-CB 3.48Å; G190-F194 PolarHBondContact O-N 3.42Å; G190-F194 VanDerWaalsContact O-N 3.11Å; Y191-F194 PolarHBondContact O-N 2.91Å; F194-V197 PolarHBondContact O-N 3.35Å; F194-G198 PolarHBondContact O-N 3.29Å
195	S	89.6	Confident	87.3	Confident	11 Å²	11	37.7 Å²	37.7	8%	0.077	21%	0.214	C	C	.	.	H	α-helix	trans	-67.1	-40.9	180	63	0	0	0	0	112.1	Y191 A192 I193 S199	Y191-S195 VanDerWaalsContact O-CB 3.27Å; Y191-S195 WeakPolarHBondContact O-CB 3.49Å; Y191-S195 PolarHBondContact O-N 3.21Å; Y191-S195 PolarHBondContact O-OG 3.46Å; A192-S195 PolarHBondContact O-OG 2.99Å; I193-S195 PolarHBondContact O-N 3.36Å; S195-S199 WeakPolarHBondContact O-CB 3.28Å; S195-S199 PolarHBondContact O-N 2.7Å; S195-S199 PolarHBondContact O-OG 2.73Å
196	A	90.6	Very high	88.1	Confident	1 Å²	1	39.5 Å²	39.5	1%	0.008	22%	0.224	C	C	.	.	H	α-helix	trans	-66.2	-41.6	177.1	0	0	0	0	0	112.2	A192 I193 F200 Y201 F294 P298	A192-A196 WeakPolarHBondContact O-CB 3.11Å; A192-A196 PolarHBondContact O-N 3.13Å; I193-A196 PolarHBondContact O-N 3.4Å; A196-F200 WeakPolarHBondContact O-CA 3.49Å; A196-F200 WeakPolarHBondContact O-CB 3.45Å; A196-F200 PolarHBondContact O-N 2.91Å; A196-Y201 HydrophobicContact CB-CD2 4.21Å; A196-Y201 HydrophobicContact CB-CE2 3.99Å; A196-Y201 WeakPolarHBondContact O-CD2 3.41Å; A196-Y201 PolarHBondContact O-N 3.48Å; A196-F294 HydrophobicContact CB-CD1 4.06Å; A196-P298 HydrophobicContact CB-CG 4.24Å
197	V	91.3	Very high	88.8	Confident	72 Å²	72	39.2 Å²	39.2	44%	0.436	22%	0.222	S	C	.	.	I	π-helix	trans	-66	-49.7	177.4	171.4	0	0	0	0	110.9	I193 F194 Y201 L202	I193-V197 HydrophobicContact CG2-CG2 4.17Å; I193-V197 WeakPolarHBondContact O-CB 3.21Å; I193-V197 VanDerWaalsContact O-CG2 3.26Å; I193-V197 WeakPolarHBondContact O-CG2 3.4Å; I193-V197 PolarHBondContact O-N 3.22Å; F194-V197 PolarHBondContact O-N 3.35Å; V197-Y201 HydrophobicContact CG2-CD2 4.35Å; V197-L202 VanDerWaalsContact O-CB 3.27Å; V197-L202 WeakPolarHBondContact O-CB 3.33Å; V197-L202 PolarHBondContact O-N 3.39Å
198	G	89.3	Confident	89.7	Confident	18 Å²	18	41.9 Å²	41.9	19%	0.186	24%	0.237	C	C	.	.	I	π-helix	trans	-67.1	-37.1	-178.5	0	0	0	0	0	113.6	F194 P203	F194-G198 PolarHBondContact O-N 3.29Å; G198-P203 WeakPolarHBondContact O-CD 3.38Å; G198-P203 WeakPolarHBondContact O-CG 3.35Å
199	S	89.6	Confident	90.1	Very high	4 Å²	4	42 Å²	42	3%	0.028	24%	0.242	C	C	.	.	I	π-helix	trans	-94.2	-27.7	-173.2	-50.1	0	0	0	0	114.1	T118 I121 I164 S195	T118-S199 WeakPolarHBondContact CG2-OG 3.2Å; T118-S199 VanDerWaalsContact OG1-CB 3.31Å; T118-S199 WeakPolarHBondContact OG1-CB 3.23Å; T118-S199 PolarHBondContact OG1-OG 2.95Å; I121-S199 WeakPolarHBondContact CB-O 3.45Å; I121-S199 VanDerWaalsContact CD1-O 3.26Å; I121-S199 WeakPolarHBondContact CD1-O 3.49Å; I121-S199 VanDerWaalsContact CG2-O 3.23Å; I121-S199 WeakPolarHBondContact CG2-O 3.32Å; I164-S199 WeakPolarHBondContact CG2-OG 3.4Å; S195-S199 WeakPolarHBondContact O-CB 3.28Å; S195-S199 PolarHBondContact O-N 2.7Å; S195-S199 PolarHBondContact O-OG 2.73Å
200	F	91.1	Very high	90.6	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	23%	0.234	C	C	.	.	I	π-helix	trans	-124.4	-62.2	-173.7	-177.7	-105.2	0	0	0	113.4	I121 A196 L202 P203 L204 F286 W290 L291 F294	I121-F200 HydrophobicContact CD1-CD2 4.26Å; A196-F200 WeakPolarHBondContact O-CA 3.49Å; A196-F200 WeakPolarHBondContact O-CB 3.45Å; A196-F200 PolarHBondContact O-N 2.91Å; F200-L202 PolarHBondContact O-N 3.02Å; F200-P203 WeakPolarHBondContact O-CD 3.43Å; F200-L204 HydrophobicContact CD1-CD2 4.49Å; F200-L204 HydrophobicContact CE1-CD2 3.75Å; F200-L204 HydrophobicContact CE2-CD2 4.46Å; F200-L204 HydrophobicContact CZ-CD2 3.74Å; F200-L204 WeakPolarHBondContact O-CB 3.25Å; F200-L204 PolarHBondContact O-N 2.95Å; F200-F286 HydrophobicContact CD2-CE1 4.45Å; F200-F286 HydrophobicContact CD2-CZ 4.19Å; F200-F286 HydrophobicContact CE2-CE1 4.09Å; F200-F286 HydrophobicContact CE2-CZ 4.14Å; F200-W290 HydrophobicContact CD2-CB 4.19Å; F200-W290 HydrophobicContact CE2-CB 3.67Å; F200-L291 HydrophobicContact CE1-CD1 3.82Å; F200-L291 HydrophobicContact CZ-CB 4.04Å; F200-L291 HydrophobicContact CZ-CD1 3.88Å; F200-F294 HydrophobicContact CB-CB 4.33Å; F200-F294 HydrophobicContact CB-CD1 3.65Å; F200-F294 HydrophobicContact CB-CD2 3.58Å; F200-F294 HydrophobicContact CB-CE1 3.73Å; F200-F294 HydrophobicContact CB-CE2 3.64Å; F200-F294 HydrophobicContact CB-CG 3.59Å; F200-F294 HydrophobicContact CB-CZ 3.73Å; F200-F294 HydrophobicContact CD1-CB 3.42Å; F200-F294 VanDerWaalsContact CD1-CB 3.42Å; F200-F294 HydrophobicContact CD1-CD1 4.35Å; F200-F294 AromaticContact CD1-CD2 3.76Å; F200-F294 HydrophobicContact CD1-CD2 3.76Å; F200-F294 AromaticContact CD1-CG 3.6Å; F200-F294 HydrophobicContact CD1-CG 3.6Å; F200-F294 HydrophobicContact CD2-CB 4.46Å; F200-F294 AromaticContact CD2-CD2 3.22Å; F200-F294 HydrophobicContact CD2-CD2 3.22Å; F200-F294 AromaticContact CD2-CE2 3.5Å; F200-F294 HydrophobicContact CD2-CE2 3.5Å; F200-F294 AromaticContact CD2-CG 3.94Å; F200-F294 HydrophobicContact CD2-CG 3.94Å; F200-F294 HydrophobicContact CD2-CZ 4.43Å; F200-F294 HydrophobicContact CE1-CB 3.72Å; F200-F294 HydrophobicContact CE1-CD2 4.22Å; F200-F294 HydrophobicContact CE1-CG 4.22Å; F200-F294 AromaticContact CE2-CD2 3.75Å; F200-F294 HydrophobicContact CE2-CD2 3.75Å; F200-F294 HydrophobicContact CE2-CE2 4.31Å; F200-F294 HydrophobicContact CG-CB 3.83Å; F200-F294 HydrophobicContact CG-CD1 4.05Å; F200-F294 AromaticContact CG-CD2 3.22Å; F200-F294 HydrophobicContact CG-CD2 3.22Å; F200-F294 HydrophobicContact CG-CE1 4.44Å; F200-F294 AromaticContact CG-CE2 3.68Å; F200-F294 HydrophobicContact CG-CE2 3.68Å; F200-F294 AromaticContact CG-CG 3.42Å; F200-F294 HydrophobicContact CG-CG 3.42Å; F200-F294 VanDerWaalsContact CG-CG 3.42Å; F200-F294 HydrophobicContact CG-CZ 4.29Å; F200-F294 HydrophobicContact CZ-CB 4.35Å; F200-F294 HydrophobicContact CZ-CD2 4.21Å
201	Y	92.4	Very high	90.5	Very high	75 Å²	75	40.3 Å²	40.3	29%	0.294	21%	0.214	S	C	.	.	I	π-helix	trans	-65.4	-42.7	-169.6	-67.2	-73.6	0	0	0	113.6	A196 V197 T205 F294	A196-Y201 HydrophobicContact CB-CD2 4.21Å; A196-Y201 HydrophobicContact CB-CE2 3.99Å; A196-Y201 WeakPolarHBondContact O-CD2 3.41Å; A196-Y201 PolarHBondContact O-N 3.48Å; V197-Y201 HydrophobicContact CG2-CD2 4.35Å; Y201-T205 WeakPolarHBondContact O-CB 3.22Å; Y201-T205 PolarHBondContact O-N 2.97Å; Y201-T205 PolarHBondContact O-OG1 3.46Å; Y201-F294 PolarHBondContact OH-O 2.88Å
202	L	93.1	Very high	90.6	Very high	103 Å²	103	43.9 Å²	43.9	54%	0.539	24%	0.239	S	C	.	.	H	α-helix	trans	-67.1	-52.2	177	175.8	75.7	0	0	0	111.3	V197 F200 L204 T205 I206	V197-L202 VanDerWaalsContact O-CB 3.27Å; V197-L202 WeakPolarHBondContact O-CB 3.33Å; V197-L202 PolarHBondContact O-N 3.39Å; F200-L202 PolarHBondContact O-N 3.02Å; L202-L204 VanDerWaalsContact C-N 3.33Å; L202-L204 PolarHBondContact O-N 3.17Å; L202-T205 PolarHBondContact O-N 3.28Å; L202-I206 HydrophobicContact CG-CD1 4.32Å; L202-I206 WeakPolarHBondContact O-CG1 3.36Å; L202-I206 PolarHBondContact O-N 3Å; L202-I206 VanDerWaalsContact O-N 3.1Å
203	P	93.1	Very high	90.7	Very high	1 Å²	1	51.1 Å²	51.1	1%	0.006	27%	0.266	C	S	.	.	H	α-helix	trans	-57.7	-41.8	174.2	-28.9	38.1	0	0	0	113.6	I121 M122 C125 G198 F200 T205 I206 I207	I121-P203 HydrophobicContact CG2-CB 3.64Å; I121-P203 HydrophobicContact CG2-CG 4.26Å; M122-P203 HydrophobicContact SD-CB 4.24Å; M122-P203 HydrophobicContact SD-CG 3.52Å; M122-P203 VanDerWaalsContact SD-CG 3.52Å; C125-P203 HydrophobicContact CB-CB 4.3Å; G198-P203 WeakPolarHBondContact O-CD 3.38Å; G198-P203 WeakPolarHBondContact O-CG 3.35Å; F200-P203 WeakPolarHBondContact O-CD 3.43Å; P203-T205 VanDerWaalsContact C-N 3.34Å; P203-T205 PolarHBondContact O-N 3.2Å; P203-I206 PolarHBondContact O-N 3.06Å; P203-I207 WeakPolarHBondContact O-CB 3.31Å; P203-I207 WeakPolarHBondContact O-CD1 3.23Å; P203-I207 WeakPolarHBondContact O-CG1 3.46Å; P203-I207 PolarHBondContact O-N 3.02Å
204	L	92.1	Very high	90.6	Very high	17 Å²	17	47.9 Å²	47.9	9%	0.089	25%	0.25	C	C	.	.	H	α-helix	trans	-59.5	-45.4	177.5	177.4	65	0	0	0	111.2	F200 L202 I206 I207 L208 V287	F200-L204 HydrophobicContact CD1-CD2 4.49Å; F200-L204 HydrophobicContact CE1-CD2 3.75Å; F200-L204 HydrophobicContact CE2-CD2 4.46Å; F200-L204 HydrophobicContact CZ-CD2 3.74Å; F200-L204 WeakPolarHBondContact O-CB 3.25Å; F200-L204 PolarHBondContact O-N 2.95Å; L202-L204 VanDerWaalsContact C-N 3.33Å; L202-L204 PolarHBondContact O-N 3.17Å; L204-I206 VanDerWaalsContact C-N 3.33Å; L204-I206 PolarHBondContact O-N 3.5Å; L204-I207 PolarHBondContact O-N 2.98Å; L204-L208 HydrophobicContact CD1-CD1 4.12Å; L204-L208 HydrophobicContact CD1-CG 4.11Å; L204-L208 HydrophobicContact CG-CD1 3.97Å; L204-L208 HydrophobicContact CG-CG 4.35Å; L204-L208 WeakPolarHBondContact O-CB 3.46Å; L204-L208 VanDerWaalsContact O-CG 3.29Å; L204-L208 WeakPolarHBondContact O-CG 3.42Å; L204-L208 PolarHBondContact O-N 3.18Å; L204-V287 HydrophobicContact CD1-CG2 3.49Å; L204-V287 VanDerWaalsContact CD1-CG2 3.49Å
205	T	93.1	Very high	90.2	Very high	84 Å²	84	51 Å²	51	52%	0.515	26%	0.26	S	S	.	.	H	α-helix	trans	-60.3	-44.9	177.4	-58.1	0	0	0	0	110.9	Y201 L202 P203 L208 V209	Y201-T205 WeakPolarHBondContact O-CB 3.22Å; Y201-T205 PolarHBondContact O-N 2.97Å; Y201-T205 PolarHBondContact O-OG1 3.46Å; L202-T205 PolarHBondContact O-N 3.28Å; P203-T205 VanDerWaalsContact C-N 3.34Å; P203-T205 PolarHBondContact O-N 3.2Å; T205-L208 PolarHBondContact O-N 3.18Å; T205-V209 WeakPolarHBondContact O-CB 3.5Å; T205-V209 VanDerWaalsContact O-CG2 3.27Å; T205-V209 WeakPolarHBondContact O-CG2 3.41Å; T205-V209 PolarHBondContact O-N 3.37Å
206	I	93.6	Very high	90	Very high	63 Å²	63	54.7 Å²	54.7	32%	0.323	28%	0.282	S	S	.	.	H	α-helix	trans	-62.3	-46.9	176.9	-63	166.2	0	0	0	110.5	C125 V129 L202 P203 L204 V209 M210	C125-I206 WeakPolarHBondContact SG-CG2 3.26Å; V129-I206 HydrophobicContact CG2-CG2 4.36Å; L202-I206 HydrophobicContact CG-CD1 4.32Å; L202-I206 WeakPolarHBondContact O-CG1 3.36Å; L202-I206 PolarHBondContact O-N 3Å; L202-I206 VanDerWaalsContact O-N 3.1Å; P203-I206 PolarHBondContact O-N 3.06Å; L204-I206 VanDerWaalsContact C-N 3.33Å; L204-I206 PolarHBondContact O-N 3.5Å; I206-V209 PolarHBondContact O-N 3.28Å; I206-M210 HydrophobicContact CG2-CG 4.13Å; I206-M210 WeakPolarHBondContact O-CB 3.17Å; I206-M210 WeakPolarHBondContact O-CG 3.23Å; I206-M210 PolarHBondContact O-N 3.42Å
207	I	91.8	Very high	89.6	Confident	1 Å²	1	56.5 Å²	56.5	1%	0.005	29%	0.293	C	S	.	.	H	α-helix	trans	-55.3	-56.1	177.2	-71	165.7	0	0	0	109.5	L124 C125 P203 L204 V209 M210 Y211 V283	L124-I207 HydrophobicContact CB-CD1 4.21Å; C125-I207 HydrophobicContact CB-CD1 4.24Å; C125-I207 HydrophobicContact CB-CG1 4.03Å; P203-I207 WeakPolarHBondContact O-CB 3.31Å; P203-I207 WeakPolarHBondContact O-CD1 3.23Å; P203-I207 WeakPolarHBondContact O-CG1 3.46Å; P203-I207 PolarHBondContact O-N 3.02Å; L204-I207 PolarHBondContact O-N 2.98Å; I207-V209 VanDerWaalsContact C-N 3.35Å; I207-V209 PolarHBondContact O-N 3.01Å; I207-M210 PolarHBondContact O-N 3.08Å; I207-M210 VanDerWaalsContact O-N 3.16Å; I207-Y211 HydrophobicContact CG2-CD2 3.72Å; I207-Y211 HydrophobicContact CG2-CE2 3.88Å; I207-Y211 VanDerWaalsContact O-CD2 3.23Å; I207-Y211 WeakPolarHBondContact O-CD2 3.49Å; I207-Y211 PolarHBondContact O-N 3.32Å; I207-V283 HydrophobicContact CG2-CB 4.4Å; I207-V283 HydrophobicContact CG2-CG1 3.53Å; I207-V283 HydrophobicContact CG2-CG2 3.92Å
208	L	91.4	Very high	88.8	Confident	85 Å²	85	54.2 Å²	54.2	45%	0.445	28%	0.282	S	S	.	.	H	α-helix	trans	-57.4	-46.2	-178.5	-69.6	174.1	0	0	0	111.8	L204 T205 M210 Y211 C212	L204-L208 HydrophobicContact CD1-CD1 4.12Å; L204-L208 HydrophobicContact CD1-CG 4.11Å; L204-L208 HydrophobicContact CG-CD1 3.97Å; L204-L208 HydrophobicContact CG-CG 4.35Å; L204-L208 WeakPolarHBondContact O-CB 3.46Å; L204-L208 VanDerWaalsContact O-CG 3.29Å; L204-L208 WeakPolarHBondContact O-CG 3.42Å; L204-L208 PolarHBondContact O-N 3.18Å; T205-L208 PolarHBondContact O-N 3.18Å; L208-M210 PolarHBondContact O-N 3.29Å; L208-Y211 PolarHBondContact O-N 3.36Å; L208-C212 WeakPolarHBondContact O-CB 3.44Å; L208-C212 PolarHBondContact O-N 3.46Å; L208-C212 PolarHBondContact O-SG 3.19Å
209	V	92.3	Very high	88.3	Confident	69 Å²	69	57 Å²	57	42%	0.418	29%	0.29	S	S	.	.	H	α-helix	trans	-61.6	-46.3	177.3	172.3	0	0	0	0	111.2	T205 I206 I207 Y211 C212 R213	T205-V209 WeakPolarHBondContact O-CB 3.5Å; T205-V209 VanDerWaalsContact O-CG2 3.27Å; T205-V209 WeakPolarHBondContact O-CG2 3.41Å; T205-V209 PolarHBondContact O-N 3.37Å; I206-V209 PolarHBondContact O-N 3.28Å; I207-V209 VanDerWaalsContact C-N 3.35Å; I207-V209 PolarHBondContact O-N 3.01Å; V209-Y211 PolarHBondContact O-N 3.49Å; V209-C212 PolarHBondContact O-N 3.47Å; V209-R213 HydrophobicContact CG1-CG 4.47Å; V209-R213 WeakPolarHBondContact O-CG 3.22Å; V209-R213 PolarHBondContact O-N 3.17Å
210	M	90.3	Very high	87.7	Confident	40 Å²	40	65.9 Å²	65.9	20%	0.197	32%	0.322	C	S	.	.	H	α-helix	trans	-63.3	-41.2	179	-69.3	-59.1	126.4	0	0	111.7	V129 Y132 I206 I207 L208 R213 V214	V129-M210 HydrophobicContact CG2-CG 3.93Å; V129-M210 HydrophobicContact CG2-SD 4.27Å; Y132-M210 HydrophobicContact CD1-SD 3.85Å; Y132-M210 HydrophobicContact CG-SD 4.02Å; I206-M210 HydrophobicContact CG2-CG 4.13Å; I206-M210 WeakPolarHBondContact O-CB 3.17Å; I206-M210 WeakPolarHBondContact O-CG 3.23Å; I206-M210 PolarHBondContact O-N 3.42Å; I207-M210 PolarHBondContact O-N 3.08Å; I207-M210 VanDerWaalsContact O-N 3.16Å; L208-M210 PolarHBondContact O-N 3.29Å; M210-R213 WeakPolarHBondContact O-CB 3.43Å; M210-R213 PolarHBondContact O-N 3.43Å; M210-V214 VanDerWaalsContact O-CG2 3.27Å; M210-V214 WeakPolarHBondContact O-CG2 3.29Å; M210-V214 PolarHBondContact O-N 3.33Å
211	Y	85.1	Confident	86.5	Confident	32 Å²	32	70.7 Å²	70.7	13%	0.125	35%	0.345	C	S	.	.	H	α-helix	trans	-69.6	-39.3	176.6	-85.1	-82.2	0	0	0	113.2	S128 I207 L208 V209 R213 V214 Y215 L279 V283	S128-Y211 WeakPolarHBondContact OG-CE2 3.42Å; I207-Y211 HydrophobicContact CG2-CD2 3.72Å; I207-Y211 HydrophobicContact CG2-CE2 3.88Å; I207-Y211 VanDerWaalsContact O-CD2 3.23Å; I207-Y211 WeakPolarHBondContact O-CD2 3.49Å; I207-Y211 PolarHBondContact O-N 3.32Å; L208-Y211 PolarHBondContact O-N 3.36Å; V209-Y211 PolarHBondContact O-N 3.49Å; Y211-R213 VanDerWaalsContact C-N 3.27Å; Y211-R213 PolarHBondContact O-N 3.19Å; Y211-V214 PolarHBondContact O-N 3.46Å; Y211-Y215 WeakPolarHBondContact O-CB 3.33Å; Y211-Y215 PolarHBondContact O-N 3.25Å; Y211-L279 HydrophobicContact CE1-CB 3.8Å; Y211-L279 WeakPolarHBondContact OH-CB 3.27Å; Y211-L279 PolarHBondContact OH-O 3.46Å; Y211-V283 HydrophobicContact CD1-CG2 4.42Å; Y211-V283 HydrophobicContact CD2-CG1 4.4Å; Y211-V283 HydrophobicContact CD2-CG2 3.59Å; Y211-V283 HydrophobicContact CE1-CG2 3.9Å; Y211-V283 HydrophobicContact CE2-CB 4.26Å; Y211-V283 HydrophobicContact CE2-CG2 2.99Å; Y211-V283 HydrophobicContact CG-CG2 4.28Å; Y211-V283 VanDerWaalsContact OH-CG2 3.25Å; Y211-V283 WeakPolarHBondContact OH-CG2 3.44Å
212	C	86.9	Confident	85.2	Confident	80 Å²	80	68.4 Å²	68.4	54%	0.541	34%	0.34	S	S	.	.	H	α-helix	trans	-57.5	-44.2	171.4	-74.4	0	0	0	0	110.4	L208 V209 Y215 V216	L208-C212 WeakPolarHBondContact O-CB 3.44Å; L208-C212 PolarHBondContact O-N 3.46Å; L208-C212 PolarHBondContact O-SG 3.19Å; V209-C212 PolarHBondContact O-N 3.47Å; C212-Y215 PolarHBondContact O-N 2.93Å; C212-V216 WeakPolarHBondContact O-CB 3.32Å; C212-V216 VanDerWaalsContact O-CG2 3.25Å; C212-V216 WeakPolarHBondContact O-CG2 3.4Å; C212-V216 PolarHBondContact O-N 3.24Å
213	R	89.2	Confident	84	Confident	153 Å²	153	67.7 Å²	67.7	58%	0.577	33%	0.334	S	S	*	.	H	α-helix	trans	-63.4	-44.7	175.6	-66.5	-77.8	-177.2	-179.1	0.3	112	Y132 V209 M210 Y211 Y215 V216 V217	Y132-R213 HydrophobicContact CD2-CB 3.76Å; Y132-R213 HydrophobicContact CE2-CB 3.56Å; Y132-R213 HydrophobicContact CE2-CG 4.45Å; V209-R213 HydrophobicContact CG1-CG 4.47Å; V209-R213 WeakPolarHBondContact O-CG 3.22Å; V209-R213 PolarHBondContact O-N 3.17Å; M210-R213 WeakPolarHBondContact O-CB 3.43Å; M210-R213 PolarHBondContact O-N 3.43Å; Y211-R213 VanDerWaalsContact C-N 3.27Å; Y211-R213 PolarHBondContact O-N 3.19Å; R213-Y215 VanDerWaalsContact C-N 3.34Å; R213-Y215 PolarHBondContact O-N 2.79Å; R213-V216 PolarHBondContact O-N 2.84Å; R213-V217 WeakPolarHBondContact O-CB 3.48Å; R213-V217 VanDerWaalsContact O-CG2 3.29Å; R213-V217 WeakPolarHBondContact O-CG2 3.08Å; R213-V217 PolarHBondContact O-N 3.32Å
214	V	85.8	Confident	82.6	Confident	7 Å²	7	69.6 Å²	69.6	4%	0.042	35%	0.354	C	S	.	.	H	α-helix	trans	-58.2	-46.4	174.6	169.5	0	0	0	0	111	Y132 V135 M210 Y211 V217 A218 A276	Y132-V214 HydrophobicContact CD2-CG2 4.08Å; Y132-V214 HydrophobicContact CG-CG2 4.48Å; V135-V214 HydrophobicContact CG1-CG1 4.41Å; V135-V214 HydrophobicContact CG2-CG1 4.32Å; M210-V214 VanDerWaalsContact O-CG2 3.27Å; M210-V214 WeakPolarHBondContact O-CG2 3.29Å; M210-V214 PolarHBondContact O-N 3.33Å; Y211-V214 PolarHBondContact O-N 3.46Å; V214-V217 PolarHBondContact O-N 3.43Å; V214-A218 WeakPolarHBondContact O-CB 3.43Å; V214-A218 PolarHBondContact O-N 3.09Å; V214-A276 HydrophobicContact CG1-CB 4.03Å
215	Y	83.4	Confident	81.2	Confident	155 Å²	155	73.3 Å²	73.3	61%	0.608	37%	0.373	S	S	*	.	H	α-helix	trans	-63.1	-47.7	179.8	177.9	-98	0	0	0	111.2	Y211 C212 R213 V217 A218 H219	Y211-Y215 WeakPolarHBondContact O-CB 3.33Å; Y211-Y215 PolarHBondContact O-N 3.25Å; C212-Y215 PolarHBondContact O-N 2.93Å; R213-Y215 VanDerWaalsContact C-N 3.34Å; R213-Y215 PolarHBondContact O-N 2.79Å; Y215-V217 PolarHBondContact O-N 2.85Å; Y215-A218 PolarHBondContact O-N 3.01Å; Y215-H219 WeakPolarHBondContact O-CB 3.31Å; Y215-H219 PolarHBondContact O-N 3.46Å
216	V	84.7	Confident	79.5	Confident	89 Å²	89	80.3 Å²	80.3	54%	0.539	39%	0.39	S	S	.	.	H	α-helix	trans	-60	-47.4	178	169.4	0	0	0	0	111	C212 R213 H219 R220	C212-V216 WeakPolarHBondContact O-CB 3.32Å; C212-V216 VanDerWaalsContact O-CG2 3.25Å; C212-V216 WeakPolarHBondContact O-CG2 3.4Å; C212-V216 PolarHBondContact O-N 3.24Å; R213-V216 PolarHBondContact O-N 2.84Å; V216-H219 PolarHBondContact O-N 3.41Å; V216-R220 VanDerWaalsContact O-CB 3.29Å; V216-R220 WeakPolarHBondContact O-CB 3.47Å; V216-R220 PolarHBondContact O-N 3.39Å
217	V	82.1	Confident	77.6	Confident	39 Å²	39	83.8 Å²	83.8	24%	0.236	41%	0.405	C	S	.	.	H	α-helix	trans	-62	-49.3	177.4	171.9	0	0	0	0	110.4	V135 R213 V214 Y215 H219 R220 E221	V135-V217 HydrophobicContact CG1-CG1 4.25Å; R213-V217 WeakPolarHBondContact O-CB 3.48Å; R213-V217 VanDerWaalsContact O-CG2 3.29Å; R213-V217 WeakPolarHBondContact O-CG2 3.08Å; R213-V217 PolarHBondContact O-N 3.32Å; V214-V217 PolarHBondContact O-N 3.43Å; Y215-V217 PolarHBondContact O-N 2.85Å; V217-H219 PolarHBondContact O-N 3.5Å; V217-R220 PolarHBondContact O-N 3.29Å; V217-E221 HydrophobicContact CG1-CG 4.45Å; V217-E221 VanDerWaalsContact O-CG 3.27Å; V217-E221 WeakPolarHBondContact O-CG 3.41Å; V217-E221 PolarHBondContact O-N 3.45Å; V217-E221 VanDerWaalsContact O-N 3.09Å
218	A	74.5	Confident	75.6	Confident	24 Å²	24	86.8 Å²	86.8	20%	0.198	44%	0.436	C	S	.	.	H	α-helix	trans	-62.7	-32	179.3	0	0	0	0	0	113.1	V214 Y215 S222	V214-A218 WeakPolarHBondContact O-CB 3.43Å; V214-A218 PolarHBondContact O-N 3.09Å; Y215-A218 PolarHBondContact O-N 3.01Å; A218-S222 WeakPolarHBondContact O-CB 3.49Å; A218-S222 PolarHBondContact O-N 3.04Å; A218-S222 PolarHBondContact O-OG 3.34Å
219	H	78.5	Confident	73.5	Confident	76 Å²	76	90.9 Å²	90.9	35%	0.352	45%	0.453	S	S	.	.	H	α-helix	trans	-75.6	-48.8	178.2	-164.9	66.5	0	0	0	111.5	Y215 V216 V217 E221 S222 Q223	Y215-H219 WeakPolarHBondContact O-CB 3.31Å; Y215-H219 PolarHBondContact O-N 3.46Å; V216-H219 PolarHBondContact O-N 3.41Å; V217-H219 PolarHBondContact O-N 3.5Å; H219-E221 VanDerWaalsContact C-N 3.33Å; H219-E221 PolarHBondContact O-N 3.03Å; H219-S222 PolarHBondContact O-N 3.29Å; H219-S222 PolarHBondContact O-OG 2.76Å; H219-Q223 PolarHBondContact NE2-NE2 3.37Å; H219-Q223 VanDerWaalsContact NE2-NE2 3.11Å; H219-Q223 PolarHBondContact O-N 3.23Å
220	R	77.3	Confident	70.9	Confident	190 Å²	190	96.8 Å²	96.8	72%	0.717	47%	0.473	S	S	*	.	H	α-helix	trans	-57.1	-45.4	179	-165.9	-178.8	-156.4	-179.6	5.7	111.9	V216 V217 S222 Q223 G224	V216-R220 VanDerWaalsContact O-CB 3.29Å; V216-R220 WeakPolarHBondContact O-CB 3.47Å; V216-R220 PolarHBondContact O-N 3.39Å; V217-R220 PolarHBondContact O-N 3.29Å; R220-S222 PolarHBondContact O-N 3.07Å; R220-Q223 PolarHBondContact O-N 2.81Å; R220-G224 PolarHBondContact O-N 3.48Å
221	E	65.4	Low	68.4	Low	102 Å²	102	100.7 Å²	100.7	48%	0.477	50%	0.499	S	S	.	.	H	α-helix	trans	-68	-35.1	177.2	-64.1	-59.3	145.3	0	0	112.1	V217 H219 Q223 G224 L225	V217-E221 HydrophobicContact CG1-CG 4.45Å; V217-E221 VanDerWaalsContact O-CG 3.27Å; V217-E221 WeakPolarHBondContact O-CG 3.41Å; V217-E221 PolarHBondContact O-N 3.45Å; V217-E221 VanDerWaalsContact O-N 3.09Å; H219-E221 VanDerWaalsContact C-N 3.33Å; H219-E221 PolarHBondContact O-N 3.03Å; E221-Q223 VanDerWaalsContact C-N 3.35Å; E221-G224 PolarHBondContact O-N 3.33Å; E221-L225 WeakPolarHBondContact O-CB 3.27Å; E221-L225 PolarHBondContact O-N 3.16Å
222	S	66.6	Low	66	Low	27 Å²	27	108.2 Å²	108.2	19%	0.189	54%	0.536	C	S	.	.	H	α-helix	trans	-71.9	-28.8	176.2	73.8	0	0	0	0	113.8	A218 H219 R220 R226	A218-S222 WeakPolarHBondContact O-CB 3.49Å; A218-S222 PolarHBondContact O-N 3.04Å; A218-S222 PolarHBondContact O-OG 3.34Å; H219-S222 PolarHBondContact O-N 3.29Å; H219-S222 PolarHBondContact O-OG 2.76Å; R220-S222 PolarHBondContact O-N 3.07Å; S222-R226 WeakPolarHBondContact O-CB 3.43Å; S222-R226 WeakPolarHBondContact O-CG 3.46Å; S222-R226 PolarHBondContact O-N 3.29Å
223	Q	66.4	Low	63.6	Low	87 Å²	87	114.6 Å²	114.6	41%	0.407	55%	0.554	S	S	.	*	H	α-helix	trans	-72.9	-47	170.6	-73.9	-175.2	-30.6	0	0	110.2	H219 R220 E221 L225 R226 E227	H219-Q223 PolarHBondContact NE2-NE2 3.37Å; H219-Q223 VanDerWaalsContact NE2-NE2 3.11Å; H219-Q223 PolarHBondContact O-N 3.23Å; R220-Q223 PolarHBondContact O-N 2.81Å; E221-Q223 VanDerWaalsContact C-N 3.35Å; Q223-L225 VanDerWaalsContact C-N 3.29Å; Q223-L225 PolarHBondContact O-N 3.06Å; Q223-R226 PolarHBondContact O-N 2.87Å; Q223-E227 WeakPolarHBondContact O-CB 3.19Å; Q223-E227 VanDerWaalsContact O-CG 3.31Å; Q223-E227 WeakPolarHBondContact O-CG 3.37Å; Q223-E227 PolarHBondContact O-N 3.45Å
224	G	64.4	Low	60.9	Low	42 Å²	42	112.3 Å²	112.3	43%	0.433	56%	0.561	S	S	.	*	H	α-helix	trans	-58.2	-37.6	176.8	0	0	0	0	0	113.9	R220 E221 E227 G228	R220-G224 PolarHBondContact O-N 3.48Å; E221-G224 PolarHBondContact O-N 3.33Å; G224-E227 PolarHBondContact O-N 3.13Å; G224-G228 PolarHBondContact O-N 3.06Å
225	L	63.3	Low	58.5	Low	94 Å²	94	119.7 Å²	119.7	49%	0.492	60%	0.6	S	S	.	*	H	α-helix	trans	-73.9	-31.2	175	-79.8	161.7	0	0	0	114.3	E221 Q223 L266	E221-L225 WeakPolarHBondContact O-CB 3.27Å; E221-L225 PolarHBondContact O-N 3.16Å; Q223-L225 VanDerWaalsContact C-N 3.29Å; Q223-L225 PolarHBondContact O-N 3.06Å; L225-L266 HydrophobicContact CD1-CD2 3.65Å; L225-L266 HydrophobicContact CD2-CD2 3.44Å; L225-L266 VanDerWaalsContact CD2-CD2 3.44Å; L225-L266 HydrophobicContact CG-CD2 4.2Å
226	R	56.7	Low	56.1	Low	232 Å²	232	117.4 Å²	117.4	88%	0.875	61%	0.607	S	S	*	*	H	α-helix	trans	-73.8	-32.4	171.9	-85.8	179.4	129.8	-162.2	-3.1	111.7	S222 Q223	S222-R226 WeakPolarHBondContact O-CB 3.43Å; S222-R226 WeakPolarHBondContact O-CG 3.46Å; S222-R226 PolarHBondContact O-N 3.29Å; Q223-R226 PolarHBondContact O-N 2.87Å
227	E	52.9	Low	53.4	Low	135 Å²	135	121.9 Å²	121.9	63%	0.631	62%	0.622	S	S	*	*	H	α-helix	trans	-81.2	-32.2	-176.2	-75.2	173.5	-172.4	0	0	112.4	Q223 G224 H229	Q223-E227 WeakPolarHBondContact O-CB 3.19Å; Q223-E227 VanDerWaalsContact O-CG 3.31Å; Q223-E227 WeakPolarHBondContact O-CG 3.37Å; Q223-E227 PolarHBondContact O-N 3.45Å; G224-E227 PolarHBondContact O-N 3.13Å; E227-H229 WeakPolarHBondContact O-CA 3.25Å; E227-H229 WeakPolarHBondContact O-CB 3.46Å; E227-H229 PolarHBondContact O-N 2.87Å
228	G	49.8	Very low	50.8	Low	64 Å²	64	128.3 Å²	128.3	66%	0.66	65%	0.65	S	S	*	*			trans	48.1	9.1	158.7	0	0	0	0	0	118.5	G224	G224-G228 PolarHBondContact O-N 3.06Å
229	H	47.4	Very low	48.7	Very low	171 Å²	171	133.3 Å²	133.3	79%	0.792	68%	0.678	S	S	*	*	S	Bend	trans	-161.8	36.5	-162.3	-128	167.7	0	0	0	112.5	E227	E227-H229 WeakPolarHBondContact O-CA 3.25Å; E227-H229 WeakPolarHBondContact O-CB 3.46Å; E227-H229 PolarHBondContact O-N 2.87Å
230	K	38.8	Very low	46.5	Very low	193 Å²	193	134.5 Å²	134.5	84%	0.839	69%	0.686	S	S	*	*	S	Bend	trans	-168	100.2	154.7	-103.9	149.2	-169.5	-173.9	0	112.1
231	T	37.2	Very low	44.6	Very low	122 Å²	122	132.9 Å²	132.9	75%	0.748	69%	0.69	S	S	*	*			trans	62.2	109.7	132.9	-32	0	0	0	0	118.2	K233	T231-K233 PolarHBondContact O-N 2.85Å; T231-K233 VanDerWaalsContact O-N 3.13Å
232	E	34.7	Very low	43.1	Very low	191 Å²	191	137 Å²	137	89%	0.893	70%	0.701	S	S	*	*			trans	-57.1	112.6	150.5	-102.3	-173	148.7	0	0	108.6	S234	E232-S234 PolarHBondContact O-N 2.77Å
233	K	37.1	Very low	42.1	Very low	214 Å²	214	143.2 Å²	143.2	93%	0.93	73%	0.731	S	S	*	*			trans	-85.5	85.8	167.6	-143.2	-178.8	-171.2	-175.5	0	107.1	T231	T231-K233 PolarHBondContact O-N 2.85Å; T231-K233 VanDerWaalsContact O-N 3.13Å
234	S	32	Very low	40.6	Very low	104 Å²	104	146.8 Å²	146.8	73%	0.727	75%	0.747	S	S	*	*			trans	-114.4	121	155.7	-161.6	0	0	0	0	107.1	E232 S236	E232-S234 PolarHBondContact O-N 2.77Å; S234-S236 PolarHBondContact O-N 3.16Å
235	D	34.9	Very low	39.7	Very low	162 Å²	162	156.7 Å²	156.7	87%	0.866	77%	0.772	S	S	*	*	S	Bend	trans	-69.7	89.1	-179.9	-165.9	24.4	0	0	0	109.1
236	S	33	Very low	38.4	Very low	107 Å²	107	155.4 Å²	155.4	75%	0.748	78%	0.781	S	S	*	*	S	Bend	trans	172.1	114.8	152.4	-74.6	0	0	0	0	107.7	S234	S234-S236 PolarHBondContact O-N 3.16Å
237	E	29.5	Very low	37.6	Very low	184 Å²	184	151.9 Å²	151.9	86%	0.86	78%	0.78	S	S	*	*			trans	57	101.7	175.6	-70.2	-174.7	147.5	0	0	117	V239	E237-V239 PolarHBondContact O-N 3.35Å
238	Q	26.6	Very low	37.5	Very low	173 Å²	173	149.5 Å²	149.5	81%	0.808	77%	0.774	S	S	*	*			trans	-58.9	87.8	169.1	-163.6	-173.2	24.4	0	0	111.2	I240	Q238-I240 VanDerWaalsContact C-N 3.32Å; Q238-I240 HydrophobicContact CG-CD1 4.43Å; Q238-I240 HydrophobicContact CG-CG1 3.97Å; Q238-I240 PolarHBondContact O-N 2.87Å
239	V	31.2	Very low	37.7	Very low	130 Å²	130	151.4 Å²	151.4	79%	0.788	77%	0.773	S	S	*	*			trans	-80	85.7	166.7	-172.6	0	0	0	0	108.3	E237 L241	E237-V239 PolarHBondContact O-N 3.35Å; V239-L241 PolarHBondContact O-N 3.24Å
240	I	30.6	Very low	37.8	Very low	101 Å²	101	146.9 Å²	146.9	52%	0.518	77%	0.766	S	S	.	*			trans	-63.4	114.8	163.1	-60.6	175.8	0	0	0	106.2	Q238 R242	Q238-I240 VanDerWaalsContact C-N 3.32Å; Q238-I240 HydrophobicContact CG-CD1 4.43Å; Q238-I240 HydrophobicContact CG-CG1 3.97Å; Q238-I240 PolarHBondContact O-N 2.87Å; I240-R242 PolarHBondContact O-N 3.39Å
241	L	37.4	Very low	38.5	Very low	155 Å²	155	144.2 Å²	144.2	81%	0.812	76%	0.76	S	S	*	*			trans	-67.9	78.9	169.5	-164.4	83	0	0	0	108.8	V239 I243	V239-L241 PolarHBondContact O-N 3.24Å; L241-I243 PolarHBondContact O-N 2.86Å
242	R	35.7	Very low	39.1	Very low	188 Å²	188	144.6 Å²	144.6	71%	0.709	75%	0.753	S	S	*	*			trans	-72.1	114.5	165.3	-112.4	-176.5	176.2	114	-1.8	106.3	I240 H244	I240-R242 PolarHBondContact O-N 3.39Å; R242-H244 PolarHBondContact O-N 2.87Å
243	I	45	Very low	40	Very low	158 Å²	158	141.7 Å²	141.7	81%	0.81	74%	0.74	S	S	*	*			trans	-64.9	88.8	172.4	-58.1	170.5	0	0	0	107.1	L241 R245	L241-I243 PolarHBondContact O-N 2.86Å; I243-R245 PolarHBondContact O-N 3.41Å
244	H	35.1	Very low	40.8	Very low	162 Å²	162	138.1 Å²	138.1	75%	0.75	73%	0.726	S	S	*	*			trans	-74.8	106.5	163.8	-86.9	-92.9	0	0	0	107.2	R242 G246	R242-H244 PolarHBondContact O-N 2.87Å; H244-G246 PolarHBondContact O-N 2.79Å; H244-G246 VanDerWaalsContact O-N 3.11Å
245	R	43.9	Very low	42	Very low	251 Å²	251	136.2 Å²	136.2	95%	0.947	71%	0.713	S	S	*	*			trans	-77.1	89.1	172.1	-174.8	177.8	160.8	124.7	-2	107.9	I243	I243-R245 PolarHBondContact O-N 3.41Å
246	G	37	Very low	43.1	Very low	67 Å²	67	134 Å²	134	69%	0.691	70%	0.7	S	S	*	*			trans	-158	114.2	173.3	0	0	0	0	0	112.2	H244	H244-G246 PolarHBondContact O-N 2.79Å; H244-G246 VanDerWaalsContact O-N 3.11Å
247	N	40.2	Very low	44.3	Very low	158 Å²	158	138.2 Å²	138.2	85%	0.845	70%	0.7	S	S	*	*			trans	13.9	133	154.6	-115.5	28.8	0	0	0	119.2
248	T	51.3	Low	45.6	Very low	85 Å²	85	133.1 Å²	133.1	52%	0.521	69%	0.685	S	S	.	*			cis	-175.7	153	-16.9	-3	0	0	0	0	106.6	A250	T248-A250 PolarHBondContact O-N 3.36Å
249	T	53.3	Low	47.3	Very low	103 Å²	103	133.7 Å²	133.7	63%	0.632	68%	0.679	S	S	*	*	S	Bend	trans	85.8	-72.3	167.7	71.6	0	0	0	0	118.8	L251 E252	T249-L251 PolarHBondContact O-N 3.31Å; T249-E252 PolarHBondContact O-N 3.48Å
250	A	50.5	Low	48.9	Very low	77 Å²	77	130.9 Å²	130.9	64%	0.636	66%	0.662	S	S	*	*	H	α-helix	trans	-69.8	-35.2	-171	0	0	0	0	0	114.8	T248	T248-A250 PolarHBondContact O-N 3.36Å
251	L	51.7	Low	50.5	Low	137 Å²	137	130.2 Å²	130.2	72%	0.717	66%	0.657	S	S	*	*	H	α-helix	trans	-76.7	-22.3	177.5	-83	158.2	0	0	0	113.1	T249 S255	T249-L251 PolarHBondContact O-N 3.31Å; L251-S255 WeakPolarHBondContact O-CB 3.33Å; L251-S255 PolarHBondContact O-N 3.48Å
252	E	51.5	Low	51.8	Low	129 Å²	129	128.4 Å²	128.4	60%	0.603	64%	0.643	S	S	*	*	H	α-helix	trans	-73.3	-40.7	177.3	-83.6	-177.8	142.8	0	0	111.3	T249 L256	T249-E252 PolarHBondContact O-N 3.48Å; E252-L256 WeakPolarHBondContact O-CA 3.22Å; E252-L256 WeakPolarHBondContact O-CB 3.43Å; E252-L256 PolarHBondContact O-N 3.48Å
253	E	52.3	Low	53.2	Low	131 Å²	131	121.6 Å²	121.6	61%	0.612	63%	0.627	S	S	*	*	H	α-helix	trans	-62.6	-42.7	173.3	-98.5	-162.8	140.2	0	0	111.8	R257	E253-R257 WeakPolarHBondContact O-CB 3.43Å; E253-R257 PolarHBondContact O-N 3.41Å
254	E	54.9	Low	54.1	Low	139 Å²	139	119.1 Å²	119.1	65%	0.65	61%	0.614	S	S	*	*	H	α-helix	trans	-71.2	-39.2	-179.1	-143.3	179.1	-165.9	0	0	112.1	S258	E254-S258 WeakPolarHBondContact O-CB 3.27Å; E254-S258 PolarHBondContact O-N 2.8Å
255	S	55.7	Low	55.5	Low	63 Å²	63	115.8 Å²	115.8	44%	0.441	60%	0.595	S	S	.	*	H	α-helix	trans	-66.5	-43.1	172.6	174.8	0	0	0	0	112.3	L251 S258 R259	L251-S255 WeakPolarHBondContact O-CB 3.33Å; L251-S255 PolarHBondContact O-N 3.48Å; S255-S258 PolarHBondContact O-N 3.48Å; S255-R259 WeakPolarHBondContact O-CB 3.34Å; S255-R259 VanDerWaalsContact O-CG 3.26Å; S255-R259 WeakPolarHBondContact O-CG 3.48Å; S255-R259 PolarHBondContact O-N 3.35Å
256	L	57.8	Low	56.6	Low	116 Å²	116	106.4 Å²	106.4	61%	0.607	56%	0.564	S	S	*	*	H	α-helix	trans	-68.2	-39.9	176.7	-164.9	99.6	0	0	0	110.6	E252 R259 T260	E252-L256 WeakPolarHBondContact O-CA 3.22Å; E252-L256 WeakPolarHBondContact O-CB 3.43Å; E252-L256 PolarHBondContact O-N 3.48Å; L256-R259 PolarHBondContact O-N 2.96Å; L256-T260 VanDerWaalsContact O-CB 3.3Å; L256-T260 WeakPolarHBondContact O-CB 3.45Å; L256-T260 WeakPolarHBondContact O-CG2 3.4Å; L256-T260 PolarHBondContact O-N 2.92Å; L256-T260 PolarHBondContact O-OG1 3.24Å
257	R	59.2	Low	57.8	Low	196 Å²	196	109.1 Å²	109.1	74%	0.74	56%	0.561	S	S	*	*	H	α-helix	trans	-65.1	-38.6	173.2	-170.3	174.9	-175.7	178.2	0.9	111.7	E253 T260 H261	E253-R257 WeakPolarHBondContact O-CB 3.43Å; E253-R257 PolarHBondContact O-N 3.41Å; R257-T260 VanDerWaalsContact CA-OG1 3.26Å; R257-T260 WeakPolarHBondContact CA-OG1 3.32Å; R257-T260 PolarHBondContact O-OG1 3.4Å; R257-H261 WeakPolarHBondContact O-CB 3.33Å; R257-H261 PolarHBondContact O-N 2.89Å
258	S	55.9	Low	58.9	Low	77 Å²	77	106.6 Å²	106.6	54%	0.538	54%	0.543	S	S	.	.	H	α-helix	trans	-68.4	-45.1	174.6	-175.3	0	0	0	0	112	E254 S255 H261 F262	E254-S258 WeakPolarHBondContact O-CB 3.27Å; E254-S258 PolarHBondContact O-N 2.8Å; S255-S258 PolarHBondContact O-N 3.48Å; S258-H261 PolarHBondContact O-N 3.36Å; S258-F262 WeakPolarHBondContact O-CB 3.35Å; S258-F262 PolarHBondContact O-N 2.88Å
259	R	62.6	Low	59.4	Low	185 Å²	185	106.1 Å²	106.1	70%	0.698	53%	0.534	S	S	*	.	H	α-helix	trans	-65.1	-41.9	176.1	-73.1	175	91.9	177.4	7.5	112.3	S255 L256 F262 A263	S255-R259 WeakPolarHBondContact O-CB 3.34Å; S255-R259 VanDerWaalsContact O-CG 3.26Å; S255-R259 WeakPolarHBondContact O-CG 3.48Å; S255-R259 PolarHBondContact O-N 3.35Å; L256-R259 PolarHBondContact O-N 2.96Å; R259-F262 PolarHBondContact O-N 2.87Å; R259-A263 VanDerWaalsContact O-CB 3.26Å; R259-A263 WeakPolarHBondContact O-CB 3.24Å; R259-A263 PolarHBondContact O-N 3.32Å
260	T	65.1	Low	59.9	Low	70 Å²	70	105.2 Å²	105.2	43%	0.429	53%	0.532	S	S	.	.	H	α-helix	trans	-67.3	-40.5	174.8	50.6	0	0	0	0	111.2	L256 R257 A263 L264	L256-T260 VanDerWaalsContact O-CB 3.3Å; L256-T260 WeakPolarHBondContact O-CB 3.45Å; L256-T260 WeakPolarHBondContact O-CG2 3.4Å; L256-T260 PolarHBondContact O-N 2.92Å; L256-T260 PolarHBondContact O-OG1 3.24Å; R257-T260 VanDerWaalsContact CA-OG1 3.26Å; R257-T260 WeakPolarHBondContact CA-OG1 3.32Å; R257-T260 PolarHBondContact O-OG1 3.4Å; T260-A263 PolarHBondContact O-N 3.34Å; T260-L264 VanDerWaalsContact O-CB 3.28Å; T260-L264 WeakPolarHBondContact O-CB 3.32Å; T260-L264 WeakPolarHBondContact O-CG 3.1Å; T260-L264 PolarHBondContact O-N 2.9Å
261	H	64	Low	60.5	Low	87 Å²	87	109.4 Å²	109.4	40%	0.403	53%	0.531	S	S	.	.	H	α-helix	trans	-64.7	-39.9	174.6	178.8	-129.4	0	0	0	112.7	R257 S258 R265	R257-H261 WeakPolarHBondContact O-CB 3.33Å; R257-H261 PolarHBondContact O-N 2.89Å; S258-H261 PolarHBondContact O-N 3.36Å; H261-R265 PolarHBondContact CE1-NE 3.1Å; H261-R265 PolarHBondContact CE1-NH2 3.45Å; H261-R265 PolarHBondContact NE2-NE 2.82Å; H261-R265 WeakPolarHBondContact O-CB 3.39Å; H261-R265 VanDerWaalsContact O-CG 3.29Å; H261-R265 WeakPolarHBondContact O-CG 2.95Å; H261-R265 PolarHBondContact O-N 3.49Å
262	F	65.4	Low	61.2	Low	118 Å²	118	105 Å²	105	52%	0.518	51%	0.507	S	S	.	.	H	α-helix	trans	-66.9	-44.3	173.6	-176.4	-105.7	0	0	0	112.1	S258 R259 L264 R265 L266	S258-F262 WeakPolarHBondContact O-CB 3.35Å; S258-F262 PolarHBondContact O-N 2.88Å; R259-F262 PolarHBondContact O-N 2.87Å; F262-L264 PolarHBondContact O-N 3.27Å; F262-R265 WeakPolarHBondContact O-CB 3.45Å; F262-R265 PolarHBondContact O-N 3.23Å; F262-L266 HydrophobicContact CD1-CD1 3.61Å; F262-L266 HydrophobicContact CD1-CG 4.39Å; F262-L266 HydrophobicContact CE1-CD1 3.27Å; F262-L266 HydrophobicContact CE1-CG 4.11Å; F262-L266 HydrophobicContact CG-CD1 4.45Å; F262-L266 HydrophobicContact CZ-CD1 3.85Å; F262-L266 HydrophobicContact CZ-CG 4.25Å; F262-L266 WeakPolarHBondContact O-CG 3.27Å; F262-L266 PolarHBondContact O-N 3.39Å
263	A	64.4	Low	61.8	Low	45 Å²	45	104 Å²	104	37%	0.372	50%	0.5	S	S	.	.	H	α-helix	trans	-62.1	-41.3	174.7	0	0	0	0	0	112.1	R259 T260 L266 L267	R259-A263 VanDerWaalsContact O-CB 3.26Å; R259-A263 WeakPolarHBondContact O-CB 3.24Å; R259-A263 PolarHBondContact O-N 3.32Å; T260-A263 PolarHBondContact O-N 3.34Å; A263-L266 PolarHBondContact O-N 2.83Å; A263-L267 WeakPolarHBondContact O-CB 3.33Å; A263-L267 VanDerWaalsContact O-CG 3.32Å; A263-L267 WeakPolarHBondContact O-CG 3.41Å; A263-L267 PolarHBondContact O-N 2.79Å
264	L	63.8	Low	62.5	Low	105 Å²	105	103.6 Å²	103.6	55%	0.55	50%	0.497	S	S	.	.	H	α-helix	trans	-65.2	-38.1	174.3	-74.4	171.3	0	0	0	112.2	T260 F262 K268	T260-L264 VanDerWaalsContact O-CB 3.28Å; T260-L264 WeakPolarHBondContact O-CB 3.32Å; T260-L264 WeakPolarHBondContact O-CG 3.1Å; T260-L264 PolarHBondContact O-N 2.9Å; F262-L264 PolarHBondContact O-N 3.27Å; L264-K268 WeakPolarHBondContact O-CG 3.03Å; L264-K268 PolarHBondContact O-N 3.25Å; L264-K268 VanDerWaalsContact O-N 3.07Å
265	R	65.8	Low	63	Low	93 Å²	93	98.5 Å²	98.5	35%	0.351	48%	0.478	S	S	.	.	H	α-helix	trans	-60.9	-51.4	171.2	-77.9	175	-177	-159.8	-3.7	109.9	L139 H261 F262 L267 K268 F269	L139-R265 VanDerWaalsContact CD1-NE 3.35Å; L139-R265 HydrophobicContact CD2-CG 4.22Å; H261-R265 PolarHBondContact CE1-NE 3.1Å; H261-R265 PolarHBondContact CE1-NH2 3.45Å; H261-R265 PolarHBondContact NE2-NE 2.82Å; H261-R265 WeakPolarHBondContact O-CB 3.39Å; H261-R265 VanDerWaalsContact O-CG 3.29Å; H261-R265 WeakPolarHBondContact O-CG 2.95Å; H261-R265 PolarHBondContact O-N 3.49Å; F262-R265 WeakPolarHBondContact O-CB 3.45Å; F262-R265 PolarHBondContact O-N 3.23Å; R265-L267 PolarHBondContact O-N 3.45Å; R265-K268 PolarHBondContact O-N 2.88Å; R265-K268 VanDerWaalsContact O-N 3.15Å; R265-F269 VanDerWaalsContact C-CD2 3.47Å; R265-F269 HydrophobicContact CB-CD2 4.16Å; R265-F269 HydrophobicContact CB-CE2 4.06Å; R265-F269 WeakPolarHBondContact O-CD2 3.46Å; R265-F269 PolarHBondContact O-N 2.96Å
266	L	65.6	Low	63.6	Low	54 Å²	54	96.2 Å²	96.2	28%	0.283	46%	0.464	S	S	.	.	H	α-helix	trans	-57.3	-44	179	-79.1	169	0	0	0	113.5	L225 F262 A263 F269 S270	L225-L266 HydrophobicContact CD1-CD2 3.65Å; L225-L266 HydrophobicContact CD2-CD2 3.44Å; L225-L266 VanDerWaalsContact CD2-CD2 3.44Å; L225-L266 HydrophobicContact CG-CD2 4.2Å; F262-L266 HydrophobicContact CD1-CD1 3.61Å; F262-L266 HydrophobicContact CD1-CG 4.39Å; F262-L266 HydrophobicContact CE1-CD1 3.27Å; F262-L266 HydrophobicContact CE1-CG 4.11Å; F262-L266 HydrophobicContact CG-CD1 4.45Å; F262-L266 HydrophobicContact CZ-CD1 3.85Å; F262-L266 HydrophobicContact CZ-CG 4.25Å; F262-L266 WeakPolarHBondContact O-CG 3.27Å; F262-L266 PolarHBondContact O-N 3.39Å; A263-L266 PolarHBondContact O-N 2.83Å; L266-F269 PolarHBondContact O-N 3.44Å; L266-S270 WeakPolarHBondContact O-CB 3.48Å; L266-S270 PolarHBondContact O-N 2.96Å
267	L	62.3	Low	64.3	Low	123 Å²	123	98.3 Å²	98.3	64%	0.644	47%	0.468	S	S	*	.	H	α-helix	trans	-64.4	-41.2	176.5	-71.8	171.6	0	0	0	111.9	A263 R265 R271	A263-L267 WeakPolarHBondContact O-CB 3.33Å; A263-L267 VanDerWaalsContact O-CG 3.32Å; A263-L267 WeakPolarHBondContact O-CG 3.41Å; A263-L267 PolarHBondContact O-N 2.79Å; R265-L267 PolarHBondContact O-N 3.45Å; L267-R271 PolarHBondContact O-N 3.24Å
268	K	64.2	Low	64.9	Low	106 Å²	106	90 Å²	90	46%	0.461	44%	0.438	S	S	.	.	H	α-helix	trans	-63	-46.3	172.7	-79.7	-178.7	178.5	176	0	111.3	L264 R265 S270 R271 E272	L264-K268 WeakPolarHBondContact O-CG 3.03Å; L264-K268 PolarHBondContact O-N 3.25Å; L264-K268 VanDerWaalsContact O-N 3.07Å; R265-K268 PolarHBondContact O-N 2.88Å; R265-K268 VanDerWaalsContact O-N 3.15Å; K268-S270 PolarHBondContact O-N 3.49Å; K268-R271 PolarHBondContact O-N 3.38Å; K268-E272 WeakPolarHBondContact O-CG 3.02Å; K268-E272 PolarHBondContact O-N 3.42Å
269	F	62	Low	65.8	Low	75 Å²	75	87.3 Å²	87.3	33%	0.329	42%	0.418	S	S	.	.	H	α-helix	trans	-59.8	-43.8	178	-81.6	-69.5	0	0	0	112.7	P138 R265 L266 R271 E272 K273	P138-F269 HydrophobicContact CB-CE1 4.48Å; P138-F269 HydrophobicContact CG-CD1 4.13Å; P138-F269 HydrophobicContact CG-CE1 3.39Å; P138-F269 HydrophobicContact CG-CE2 4.05Å; P138-F269 HydrophobicContact CG-CZ 3.32Å; R265-F269 VanDerWaalsContact C-CD2 3.47Å; R265-F269 HydrophobicContact CB-CD2 4.16Å; R265-F269 HydrophobicContact CB-CE2 4.06Å; R265-F269 WeakPolarHBondContact O-CD2 3.46Å; R265-F269 PolarHBondContact O-N 2.96Å; L266-F269 PolarHBondContact O-N 3.44Å; F269-R271 VanDerWaalsContact C-N 3.31Å; F269-R271 PolarHBondContact O-N 3.19Å; F269-E272 PolarHBondContact O-N 2.89Å; F269-K273 PolarHBondContact O-N 2.84Å
270	S	62.7	Low	66.5	Low	84 Å²	84	80.1 Å²	80.1	59%	0.587	40%	0.402	S	S	*	.	H	α-helix	trans	-60.6	-41	177.3	-177.6	0	0	0	0	112	L266 K268 K273 K274	L266-S270 WeakPolarHBondContact O-CB 3.48Å; L266-S270 PolarHBondContact O-N 2.96Å; K268-S270 PolarHBondContact O-N 3.49Å; S270-K273 PolarHBondContact O-N 3.33Å; S270-K274 PolarHBondContact O-N 3.5Å
271	R	62.7	Low	67.3	Low	165 Å²	165	81 Å²	81	62%	0.623	40%	0.402	S	S	*	.	H	α-helix	trans	-65.9	-42.7	175	-171.8	174	64.4	-162.3	1.2	112.3	L267 K268 F269 K273 K274 A275	L267-R271 PolarHBondContact O-N 3.24Å; K268-R271 PolarHBondContact O-N 3.38Å; F269-R271 VanDerWaalsContact C-N 3.31Å; F269-R271 PolarHBondContact O-N 3.19Å; R271-K273 VanDerWaalsContact C-N 3.34Å; R271-K273 PolarHBondContact O-N 2.96Å; R271-K274 PolarHBondContact O-N 2.96Å; R271-A275 PolarHBondContact O-N 3.42Å; R271-A275 VanDerWaalsContact O-N 3.14Å
272	E	66.8	Low	68.1	Low	43 Å²	43	77 Å²	77	20%	0.201	38%	0.384	C	S	.	.	H	α-helix	trans	-65.6	-34.7	176.5	-66.5	-58.3	143.8	0	0	111.9	R131 K268 F269 K274 A275 A276	R131-E272 IonicContact NH1-OE2 3.11Å; R131-E272 PolarHBondContact NH1-OE2 3.5Å; R131-E272 VanDerWaalsContact NH1-OE2 3.16Å; K268-E272 WeakPolarHBondContact O-CG 3.02Å; K268-E272 PolarHBondContact O-N 3.42Å; F269-E272 PolarHBondContact O-N 2.89Å; E272-K274 PolarHBondContact O-N 2.84Å; E272-A275 CarbonylContact O-C 3.57Å; E272-A275 WeakPolarHBondContact O-CB 3.36Å; E272-A275 PolarHBondContact O-N 3.01Å; E272-A276 PolarHBondContact O-N 3.43Å
273	K	64.8	Low	69	Low	109 Å²	109	72 Å²	72	47%	0.474	36%	0.364	S	S	.	.	H	α-helix	trans	-63.5	-40	174.5	-175.7	171.6	179.7	167.7	0	112.5	F269 S270 R271 A275 A276 K277	F269-K273 PolarHBondContact O-N 2.84Å; S270-K273 PolarHBondContact O-N 3.33Å; R271-K273 VanDerWaalsContact C-N 3.34Å; R271-K273 PolarHBondContact O-N 2.96Å; K273-A275 VanDerWaalsContact C-N 3.31Å; K273-A276 PolarHBondContact O-N 3.17Å; K273-K277 PolarHBondContact O-N 2.96Å
274	K	66.9	Low	70	Confident	122 Å²	122	71.4 Å²	71.4	53%	0.53	36%	0.362	S	S	.	.	H	α-helix	trans	-64.6	-37.8	174.2	-171.3	175.8	179.3	178.3	0	111.5	S270 R271 E272 T278	S270-K274 PolarHBondContact O-N 3.5Å; R271-K274 PolarHBondContact O-N 2.96Å; E272-K274 PolarHBondContact O-N 2.84Å; K274-T278 PolarHBondContact O-N 3.36Å; K274-T278 PolarHBondContact O-OG1 3.23Å
275	A	64.7	Low	71.1	Confident	32 Å²	32	68 Å²	68	26%	0.264	35%	0.346	S	S	.	.	H	α-helix	trans	-66.2	-40.7	172.7	0	0	0	0	0	111.9	R271 E272 K273 K277 T278 L279	R271-A275 PolarHBondContact O-N 3.42Å; R271-A275 VanDerWaalsContact O-N 3.14Å; E272-A275 CarbonylContact O-C 3.57Å; E272-A275 WeakPolarHBondContact O-CB 3.36Å; E272-A275 PolarHBondContact O-N 3.01Å; K273-A275 VanDerWaalsContact C-N 3.31Å; A275-K277 VanDerWaalsContact C-N 3.35Å; A275-K277 PolarHBondContact O-N 3.41Å; A275-T278 VanDerWaalsContact O-CB 3.23Å; A275-T278 WeakPolarHBondContact O-CB 3.32Å; A275-T278 PolarHBondContact O-N 2.84Å; A275-L279 WeakPolarHBondContact O-CD1 3.37Å; A275-L279 WeakPolarHBondContact O-CG 3.41Å; A275-L279 PolarHBondContact O-N 3.45Å
276	A	67.9	Low	72.1	Confident	16 Å²	16	63.6 Å²	63.6	13%	0.132	33%	0.33	C	S	.	.	H	α-helix	trans	-60.2	-40.1	177.3	0	0	0	0	0	113	V135 V214 E272 K273 T278 L279 G280	V135-A276 HydrophobicContact CG2-CB 4.41Å; V214-A276 HydrophobicContact CG1-CB 4.03Å; E272-A276 PolarHBondContact O-N 3.43Å; K273-A276 PolarHBondContact O-N 3.17Å; A276-T278 VanDerWaalsContact C-N 3.33Å; A276-T278 PolarHBondContact O-N 3.13Å; A276-L279 PolarHBondContact O-N 3.23Å; A276-G280 PolarHBondContact O-N 2.68Å; A276-G280 VanDerWaalsContact O-N 3.07Å
277	K	74.3	Confident	73.2	Confident	160 Å²	160	62.6 Å²	62.6	70%	0.696	33%	0.326	S	S	*	.	H	α-helix	trans	-59	-44.7	175	-179.1	178.7	178.1	178.2	0	112.1	K273 A275 L279 G280 I281	K273-K277 PolarHBondContact O-N 2.96Å; A275-K277 VanDerWaalsContact C-N 3.35Å; A275-K277 PolarHBondContact O-N 3.41Å; K277-L279 VanDerWaalsContact C-N 3.29Å; K277-L279 PolarHBondContact O-N 3.31Å; K277-G280 PolarHBondContact O-N 3.37Å; K277-I281 PolarHBondContact O-N 3.34Å
278	T	71.8	Confident	74.5	Confident	20 Å²	20	62.8 Å²	62.8	12%	0.123	33%	0.327	C	S	.	.	H	α-helix	trans	-56.9	-45.3	178.3	-64.6	0	0	0	0	111.7	K274 A275 A276 I281 V282 S334	K274-T278 PolarHBondContact O-N 3.36Å; K274-T278 PolarHBondContact O-OG1 3.23Å; A275-T278 VanDerWaalsContact O-CB 3.23Å; A275-T278 WeakPolarHBondContact O-CB 3.32Å; A275-T278 PolarHBondContact O-N 2.84Å; A276-T278 VanDerWaalsContact C-N 3.33Å; A276-T278 PolarHBondContact O-N 3.13Å; T278-I281 WeakPolarHBondContact O-CB 3.43Å; T278-I281 PolarHBondContact O-N 3.26Å; T278-V282 PolarHBondContact O-N 3.23Å; T278-S334 WeakPolarHBondContact CG2-OG 3.39Å; T278-S334 WeakPolarHBondContact OG1-CB 3.35Å
279	L	73	Confident	75.8	Confident	22 Å²	22	58 Å²	58	12%	0.115	31%	0.307	C	S	.	.	H	α-helix	trans	-71	-35.2	-176.4	-70.9	156.8	0	0	0	111.9	I127 R131 Y211 A275 A276 K277 I281 V282 V283	I127-L279 HydrophobicContact CG2-CD2 3.87Å; R131-L279 HydrophobicContact CB-CD1 3.89Å; R131-L279 HydrophobicContact CG-CD1 3.34Å; R131-L279 HydrophobicContact CG-CD2 4.01Å; R131-L279 HydrophobicContact CG-CG 4.26Å; Y211-L279 HydrophobicContact CE1-CB 3.8Å; Y211-L279 WeakPolarHBondContact OH-CB 3.27Å; Y211-L279 PolarHBondContact OH-O 3.46Å; A275-L279 WeakPolarHBondContact O-CD1 3.37Å; A275-L279 WeakPolarHBondContact O-CG 3.41Å; A275-L279 PolarHBondContact O-N 3.45Å; A276-L279 PolarHBondContact O-N 3.23Å; K277-L279 VanDerWaalsContact C-N 3.29Å; K277-L279 PolarHBondContact O-N 3.31Å; L279-I281 VanDerWaalsContact C-N 3.26Å; L279-I281 PolarHBondContact O-N 3.02Å; L279-V282 WeakPolarHBondContact O-CB 3.11Å; L279-V282 PolarHBondContact O-N 3.46Å; L279-V283 WeakPolarHBondContact O-CG2 3.04Å; L279-V283 PolarHBondContact O-N 3.43Å
280	G	77.5	Confident	77.1	Confident	34 Å²	34	54.9 Å²	54.9	35%	0.351	29%	0.293	S	S	.	.	H	α-helix	trans	-59.6	-35.7	170.2	0	0	0	0	0	113	A276 K277 G284	A276-G280 PolarHBondContact O-N 2.68Å; A276-G280 VanDerWaalsContact O-N 3.07Å; K277-G280 PolarHBondContact O-N 3.37Å; G280-G284 PolarHBondContact O-N 3.35Å
281	I	81.7	Confident	78.5	Confident	87 Å²	87	53.7 Å²	53.7	45%	0.446	28%	0.28	S	S	.	.	H	α-helix	trans	-66.8	-45.3	173.9	-62.1	167.2	0	0	0	110.6	K277 T278 L279 V283 G284 C285 I330	K277-I281 PolarHBondContact O-N 3.34Å; T278-I281 WeakPolarHBondContact O-CB 3.43Å; T278-I281 PolarHBondContact O-N 3.26Å; L279-I281 VanDerWaalsContact C-N 3.26Å; L279-I281 PolarHBondContact O-N 3.02Å; I281-V283 VanDerWaalsContact C-N 3.29Å; I281-V283 PolarHBondContact O-N 3.11Å; I281-G284 PolarHBondContact O-N 3.31Å; I281-C285 PolarHBondContact O-N 3.1Å; I281-C285 PolarHBondContact O-SG 3.22Å; I281-I330 HydrophobicContact CG2-CD1 4.45Å
282	V	82.1	Confident	79.8	Confident	4 Å²	4	47.8 Å²	47.8	2%	0.024	26%	0.263	C	S	.	.	H	α-helix	trans	-54.7	-47	177	178.5	0	0	0	0	111	L124 T278 L279 F286 I330	L124-V282 HydrophobicContact CD2-CG1 3.7Å; T278-V282 PolarHBondContact O-N 3.23Å; L279-V282 WeakPolarHBondContact O-CB 3.11Å; L279-V282 PolarHBondContact O-N 3.46Å; V282-F286 WeakPolarHBondContact O-CB 3.44Å; V282-F286 PolarHBondContact O-N 3.17Å; V282-I330 HydrophobicContact CB-CD1 4.36Å; V282-I330 HydrophobicContact CG2-CB 4.31Å; V282-I330 HydrophobicContact CG2-CD1 4Å; V282-I330 HydrophobicContact CG2-CG2 3.5Å
283	V	82.8	Confident	80.9	Confident	13 Å²	13	46.4 Å²	46.4	8%	0.079	26%	0.256	C	S	.	.	H	α-helix	trans	-66.4	-44	179.2	177.6	0	0	0	0	112.1	I207 Y211 L279 I281 C285 F286 V287	I207-V283 HydrophobicContact CG2-CB 4.4Å; I207-V283 HydrophobicContact CG2-CG1 3.53Å; I207-V283 HydrophobicContact CG2-CG2 3.92Å; Y211-V283 HydrophobicContact CD1-CG2 4.42Å; Y211-V283 HydrophobicContact CD2-CG1 4.4Å; Y211-V283 HydrophobicContact CD2-CG2 3.59Å; Y211-V283 HydrophobicContact CE1-CG2 3.9Å; Y211-V283 HydrophobicContact CE2-CB 4.26Å; Y211-V283 HydrophobicContact CE2-CG2 2.99Å; Y211-V283 HydrophobicContact CG-CG2 4.28Å; Y211-V283 VanDerWaalsContact OH-CG2 3.25Å; Y211-V283 WeakPolarHBondContact OH-CG2 3.44Å; L279-V283 WeakPolarHBondContact O-CG2 3.04Å; L279-V283 PolarHBondContact O-N 3.43Å; I281-V283 VanDerWaalsContact C-N 3.29Å; I281-V283 PolarHBondContact O-N 3.11Å; V283-C285 VanDerWaalsContact C-N 3.34Å; V283-C285 PolarHBondContact O-N 2.97Å; V283-F286 WeakPolarHBondContact O-CB 3.45Å; V283-F286 PolarHBondContact O-N 3.35Å; V283-V287 HydrophobicContact CG1-CG2 4.27Å; V283-V287 WeakPolarHBondContact O-CG2 3.38Å; V283-V287 PolarHBondContact O-N 3.45Å
284	G	85.4	Confident	81.9	Confident	32 Å²	32	41.8 Å²	41.8	33%	0.33	24%	0.236	S	C	.	.	H	α-helix	trans	-58	-49.2	178.2	0	0	0	0	0	111.1	G280 I281 F286 V287 L288	G280-G284 PolarHBondContact O-N 3.35Å; I281-G284 PolarHBondContact O-N 3.31Å; G284-F286 VanDerWaalsContact C-N 3.32Å; G284-F286 PolarHBondContact O-N 2.82Å; G284-V287 PolarHBondContact O-N 2.89Å; G284-L288 WeakPolarHBondContact O-CB 3.3Å; G284-L288 WeakPolarHBondContact O-CG 3.26Å; G284-L288 PolarHBondContact O-N 3.2Å
285	C	88.4	Confident	82.9	Confident	34 Å²	34	39.8 Å²	39.8	23%	0.23	23%	0.23	C	C	.	.	H	α-helix	trans	-59.1	-43.7	174.9	-69.3	0	0	0	0	111.9	I281 V283 L288 C289 I326 I330	I281-C285 PolarHBondContact O-N 3.1Å; I281-C285 PolarHBondContact O-SG 3.22Å; V283-C285 VanDerWaalsContact C-N 3.34Å; V283-C285 PolarHBondContact O-N 2.97Å; C285-L288 PolarHBondContact O-N 3.48Å; C285-C289 WeakPolarHBondContact O-CB 3.29Å; C285-C289 PolarHBondContact O-N 2.94Å; C285-C289 PolarHBondContact O-SG 2.94Å; C285-I326 HydrophobicContact CB-CD1 4.26Å; C285-I326 HydrophobicContact CB-CG2 4.11Å; C285-I330 HydrophobicContact CB-CD1 4.24Å
286	F	87.1	Confident	84	Confident	1 Å²	1	39.2 Å²	39.2	0%	0.004	22%	0.223	C	C	.	.	H	α-helix	trans	-58.2	-50.7	177.6	170.5	-98.2	0	0	0	112.7	I121 L124 F200 V282 V283 G284 L288 C289 W290 N323	I121-F286 HydrophobicContact CB-CE2 4.36Å; I121-F286 HydrophobicContact CB-CZ 4.05Å; I121-F286 HydrophobicContact CD1-CE2 4.23Å; I121-F286 HydrophobicContact CD1-CZ 3.9Å; I121-F286 HydrophobicContact CG1-CE2 3.57Å; I121-F286 HydrophobicContact CG1-CZ 3.5Å; I121-F286 VanDerWaalsContact CG1-CZ 3.5Å; I121-F286 HydrophobicContact CG2-CE1 4.19Å; I121-F286 HydrophobicContact CG2-CE2 4.34Å; I121-F286 HydrophobicContact CG2-CZ 3.58Å; L124-F286 HydrophobicContact CD1-CB 3.98Å; L124-F286 HydrophobicContact CD1-CD1 4.27Å; L124-F286 HydrophobicContact CD1-CD2 3.26Å; L124-F286 HydrophobicContact CD1-CE2 3.83Å; L124-F286 HydrophobicContact CD1-CG 3.53Å; F200-F286 HydrophobicContact CD2-CE1 4.45Å; F200-F286 HydrophobicContact CD2-CZ 4.19Å; F200-F286 HydrophobicContact CE2-CE1 4.09Å; F200-F286 HydrophobicContact CE2-CZ 4.14Å; V282-F286 WeakPolarHBondContact O-CB 3.44Å; V282-F286 PolarHBondContact O-N 3.17Å; V283-F286 WeakPolarHBondContact O-CB 3.45Å; V283-F286 PolarHBondContact O-N 3.35Å; G284-F286 VanDerWaalsContact C-N 3.32Å; G284-F286 PolarHBondContact O-N 2.82Å; F286-L288 VanDerWaalsContact C-N 3.33Å; F286-L288 PolarHBondContact O-N 2.03Å; F286-C289 PolarHBondContact O-N 2.99Å; F286-W290 AromaticContact CD2-CD1 3.36Å; F286-W290 HydrophobicContact CD2-CG 4.28Å; F286-W290 AromaticContact CD2-NE1 3.93Å; F286-W290 HydrophobicContact CE2-CB 4.18Å; F286-W290 AromaticContact CE2-CD1 3.08Å; F286-W290 AromaticContact CE2-CG 3.69Å; F286-W290 HydrophobicContact CE2-CG 3.69Å; F286-W290 AromaticContact CE2-NE1 3.6Å; F286-W290 HydrophobicContact CZ-CB 4.15Å; F286-W290 AromaticContact CZ-CD1 3.91Å; F286-W290 HydrophobicContact CZ-CG 4.1Å; F286-W290 PolarHBondContact O-N 3.21Å; F286-N323 WeakPolarHBondContact CA-OD1 3.4Å
287	V	87.9	Confident	84.8	Confident	32 Å²	32	39 Å²	39	19%	0.194	22%	0.22	C	C	.	.	H	α-helix	trans	-61.5	-44.1	179.2	175.2	0	0	0	0	110.5	L204 V283 G284 C289 W290 L291	L204-V287 HydrophobicContact CD1-CG2 3.49Å; L204-V287 VanDerWaalsContact CD1-CG2 3.49Å; V283-V287 HydrophobicContact CG1-CG2 4.27Å; V283-V287 WeakPolarHBondContact O-CG2 3.38Å; V283-V287 PolarHBondContact O-N 3.45Å; G284-V287 PolarHBondContact O-N 2.89Å; V287-C289 VanDerWaalsContact C-N 3.27Å; V287-C289 PolarHBondContact O-N 3.43Å; V287-W290 PolarHBondContact O-N 3Å; V287-L291 HydrophobicContact CG1-CB 4.23Å; V287-L291 HydrophobicContact CG1-CD2 4.19Å; V287-L291 WeakPolarHBondContact O-CB 3.44Å; V287-L291 PolarHBondContact O-N 3.38Å
288	L	90.3	Very high	85.2	Confident	128 Å²	128	32.1 Å²	32.1	67%	0.67	19%	0.192	S	C	*	.	H	α-helix	trans	-62.6	-34.6	178.6	-69.9	171.4	0	0	0	112.7	G284 C285 F286 P292	G284-L288 WeakPolarHBondContact O-CB 3.3Å; G284-L288 WeakPolarHBondContact O-CG 3.26Å; G284-L288 PolarHBondContact O-N 3.2Å; C285-L288 PolarHBondContact O-N 3.48Å; F286-L288 VanDerWaalsContact C-N 3.33Å; F286-L288 PolarHBondContact O-N 2.03Å; L288-P292 WeakPolarHBondContact O-CD 3.28Å
289	C	91.1	Very high	85.8	Confident	6 Å²	6	34.7 Å²	34.7	4%	0.041	20%	0.204	C	C	.	.	H	α-helix	trans	-78.2	-41.5	-179.2	-65.7	0	0	0	0	112.7	C285 F286 V287 L319 G320 N323 I326	C285-C289 WeakPolarHBondContact O-CB 3.29Å; C285-C289 PolarHBondContact O-N 2.94Å; C285-C289 PolarHBondContact O-SG 2.94Å; F286-C289 PolarHBondContact O-N 2.99Å; V287-C289 VanDerWaalsContact C-N 3.27Å; V287-C289 PolarHBondContact O-N 3.43Å; C289-L319 WeakPolarHBondContact CB-O 3.33Å; C289-G320 PolarHBondContact O-N 3.26Å; C289-N323 HydrophobicContact CB-CB 3.96Å; C289-I326 VanDerWaalsContact SG-CD1 3.51Å
290	W	89.9	Confident	86.2	Confident	9 Å²	9	34.2 Å²	34.2	3%	0.034	20%	0.204	C	C	.	.	H	α-helix	trans	-97.4	-30	-170	-78.3	99.3	0	0	0	114.9	C117 F200 F286 V287 P292 F293 F294 G320 N323	C117-W290 HydrophobicContact CB-CH2 3.91Å; C117-W290 HydrophobicContact CB-CZ2 4.4Å; C117-W290 HydrophobicContact CB-CZ3 4.48Å; C117-W290 WeakPolarHBondContact SG-CH2 3.48Å; F200-W290 HydrophobicContact CD2-CB 4.19Å; F200-W290 HydrophobicContact CE2-CB 3.67Å; F286-W290 AromaticContact CD2-CD1 3.36Å; F286-W290 HydrophobicContact CD2-CG 4.28Å; F286-W290 AromaticContact CD2-NE1 3.93Å; F286-W290 HydrophobicContact CE2-CB 4.18Å; F286-W290 AromaticContact CE2-CD1 3.08Å; F286-W290 AromaticContact CE2-CG 3.69Å; F286-W290 HydrophobicContact CE2-CG 3.69Å; F286-W290 AromaticContact CE2-NE1 3.6Å; F286-W290 HydrophobicContact CZ-CB 4.15Å; F286-W290 AromaticContact CZ-CD1 3.91Å; F286-W290 HydrophobicContact CZ-CG 4.1Å; F286-W290 PolarHBondContact O-N 3.21Å; V287-W290 PolarHBondContact O-N 3Å; W290-P292 VanDerWaalsContact C-CD 3.46Å; W290-F293 HydrophobicContact CE3-CD1 4.31Å; W290-F293 HydrophobicContact CZ3-CD1 4.18Å; W290-F293 PolarHBondContact O-N 2.85Å; W290-F294 HydrophobicContact CB-CD2 4.11Å; W290-F294 HydrophobicContact CB-CE2 4.2Å; W290-F294 HydrophobicContact CD2-CE2 4.01Å; W290-F294 AromaticContact CE3-CD2 3.98Å; W290-F294 HydrophobicContact CE3-CD2 3.98Å; W290-F294 AromaticContact CE3-CE2 3.3Å; W290-F294 HydrophobicContact CE3-CE2 3.3Å; W290-F294 HydrophobicContact CE3-CZ 4.1Å; W290-F294 HydrophobicContact CG-CE2 4.42Å; W290-F294 AromaticContact CZ3-CE2 3.99Å; W290-F294 HydrophobicContact CZ3-CE2 3.99Å; W290-F294 HydrophobicContact CZ3-CZ 4.36Å; W290-F294 VanDerWaalsContact O-CD2 3.32Å; W290-F294 WeakPolarHBondContact O-CD2 3.48Å; W290-F294 PolarHBondContact O-N 3Å; W290-F294 VanDerWaalsContact O-N 3.17Å; W290-G320 WeakPolarHBondContact CZ2-O 3.27Å; W290-G320 PolarHBondContact NE1-O 3.33Å; W290-N323 PolarHBondContact NE1-ND2 3.37Å
291	L	90.3	Very high	86.3	Confident	59 Å²	59	33.4 Å²	33.4	31%	0.309	19%	0.193	S	C	.	.	H	α-helix	trans	-55.6	-43.6	-178.3	-177.7	66.9	0	0	0	113.1	F200 V287 F293 F294 L295	F200-L291 HydrophobicContact CE1-CD1 3.82Å; F200-L291 HydrophobicContact CZ-CB 4.04Å; F200-L291 HydrophobicContact CZ-CD1 3.88Å; V287-L291 HydrophobicContact CG1-CB 4.23Å; V287-L291 HydrophobicContact CG1-CD2 4.19Å; V287-L291 WeakPolarHBondContact O-CB 3.44Å; V287-L291 PolarHBondContact O-N 3.38Å; L291-F293 VanDerWaalsContact C-N 3.31Å; L291-F293 PolarHBondContact O-N 3.11Å; L291-F294 PolarHBondContact O-N 3.49Å; L291-L295 HydrophobicContact CD1-CD1 4.13Å; L291-L295 HydrophobicContact CD1-CG 4.1Å; L291-L295 HydrophobicContact CG-CD1 3.91Å; L291-L295 HydrophobicContact CG-CG 4.31Å; L291-L295 VanDerWaalsContact O-CG 3.29Å; L291-L295 WeakPolarHBondContact O-CG 3.38Å; L291-L295 PolarHBondContact O-N 3.07Å
292	P	91.9	Very high	86.3	Confident	41 Å²	41	33 Å²	33	27%	0.266	19%	0.191	S	C	.	.	H	α-helix	trans	-59.7	-40.6	-179.6	-26.2	38	0	0	0	113.1	L288 W290 V296 T316 L319	L288-P292 WeakPolarHBondContact O-CD 3.28Å; W290-P292 VanDerWaalsContact C-CD 3.46Å; P292-V296 WeakPolarHBondContact O-CG2 3.15Å; P292-V296 PolarHBondContact O-N 3.36Å; P292-V296 VanDerWaalsContact O-N 3.12Å; P292-T316 HydrophobicContact CB-CG2 3.58Å; P292-L319 HydrophobicContact CB-CD2 4.46Å; P292-L319 HydrophobicContact CG-CD2 3.93Å
293	F	88.1	Confident	86.4	Confident	14 Å²	14	38.2 Å²	38.2	6%	0.061	21%	0.213	C	C	.	.	H	α-helix	trans	-67.9	-47.3	179.6	177.8	-107.1	0	0	0	111.9	W290 L291 L295 V296 L297 F313 F317	W290-F293 HydrophobicContact CE3-CD1 4.31Å; W290-F293 HydrophobicContact CZ3-CD1 4.18Å; W290-F293 PolarHBondContact O-N 2.85Å; L291-F293 VanDerWaalsContact C-N 3.31Å; L291-F293 PolarHBondContact O-N 3.11Å; F293-L295 PolarHBondContact O-N 2.93Å; F293-V296 PolarHBondContact O-N 3.21Å; F293-L297 HydrophobicContact CE1-CD2 4.21Å; F293-L297 HydrophobicContact CZ-CB 4.43Å; F293-L297 HydrophobicContact CZ-CD1 4.35Å; F293-L297 HydrophobicContact CZ-CD2 4.24Å; F293-L297 WeakPolarHBondContact O-CB 3.41Å; F293-L297 PolarHBondContact O-N 2.81Å; F293-F313 HydrophobicContact CE2-CE1 4.49Å; F293-F313 AromaticContact CE2-CE2 3.91Å; F293-F313 HydrophobicContact CE2-CE2 3.91Å; F293-F313 AromaticContact CE2-CZ 3.81Å; F293-F313 HydrophobicContact CE2-CZ 3.81Å; F293-F313 HydrophobicContact CZ-CZ 4.49Å; F293-F317 HydrophobicContact CD2-CB 4.2Å; F293-F317 HydrophobicContact CD2-CD2 4.03Å; F293-F317 HydrophobicContact CE2-CB 4.28Å; F293-F317 AromaticContact CE2-CD2 3.49Å; F293-F317 HydrophobicContact CE2-CD2 3.49Å; F293-F317 VanDerWaalsContact CE2-CD2 3.49Å; F293-F317 HydrophobicContact CE2-CE2 4.29Å; F293-F317 HydrophobicContact CE2-CG 4.37Å; F293-F317 AromaticContact CZ-CD2 3.83Å; F293-F317 HydrophobicContact CZ-CD2 3.83Å; F293-F317 HydrophobicContact CZ-CE2 4.22Å
294	F	87.2	Confident	86.1	Confident	12 Å²	12	42.4 Å²	42.4	5%	0.053	24%	0.241	C	C	.	.	H	α-helix	trans	-72.2	-11.6	-179.4	-75.3	-70.6	0	0	0	114.3	I121 A196 F200 Y201 W290 L291 P298	I121-F294 HydrophobicContact CD1-CE2 3.91Å; I121-F294 HydrophobicContact CD1-CZ 4.09Å; A196-F294 HydrophobicContact CB-CD1 4.06Å; F200-F294 HydrophobicContact CB-CB 4.33Å; F200-F294 HydrophobicContact CB-CD1 3.65Å; F200-F294 HydrophobicContact CB-CD2 3.58Å; F200-F294 HydrophobicContact CB-CE1 3.73Å; F200-F294 HydrophobicContact CB-CE2 3.64Å; F200-F294 HydrophobicContact CB-CG 3.59Å; F200-F294 HydrophobicContact CB-CZ 3.73Å; F200-F294 HydrophobicContact CD1-CB 3.42Å; F200-F294 VanDerWaalsContact CD1-CB 3.42Å; F200-F294 HydrophobicContact CD1-CD1 4.35Å; F200-F294 AromaticContact CD1-CD2 3.76Å; F200-F294 HydrophobicContact CD1-CD2 3.76Å; F200-F294 AromaticContact CD1-CG 3.6Å; F200-F294 HydrophobicContact CD1-CG 3.6Å; F200-F294 HydrophobicContact CD2-CB 4.46Å; F200-F294 AromaticContact CD2-CD2 3.22Å; F200-F294 HydrophobicContact CD2-CD2 3.22Å; F200-F294 AromaticContact CD2-CE2 3.5Å; F200-F294 HydrophobicContact CD2-CE2 3.5Å; F200-F294 AromaticContact CD2-CG 3.94Å; F200-F294 HydrophobicContact CD2-CG 3.94Å; F200-F294 HydrophobicContact CD2-CZ 4.43Å; F200-F294 HydrophobicContact CE1-CB 3.72Å; F200-F294 HydrophobicContact CE1-CD2 4.22Å; F200-F294 HydrophobicContact CE1-CG 4.22Å; F200-F294 AromaticContact CE2-CD2 3.75Å; F200-F294 HydrophobicContact CE2-CD2 3.75Å; F200-F294 HydrophobicContact CE2-CE2 4.31Å; F200-F294 HydrophobicContact CG-CB 3.83Å; F200-F294 HydrophobicContact CG-CD1 4.05Å; F200-F294 AromaticContact CG-CD2 3.22Å; F200-F294 HydrophobicContact CG-CD2 3.22Å; F200-F294 HydrophobicContact CG-CE1 4.44Å; F200-F294 AromaticContact CG-CE2 3.68Å; F200-F294 HydrophobicContact CG-CE2 3.68Å; F200-F294 AromaticContact CG-CG 3.42Å; F200-F294 HydrophobicContact CG-CG 3.42Å; F200-F294 VanDerWaalsContact CG-CG 3.42Å; F200-F294 HydrophobicContact CG-CZ 4.29Å; F200-F294 HydrophobicContact CZ-CB 4.35Å; F200-F294 HydrophobicContact CZ-CD2 4.21Å; Y201-F294 PolarHBondContact OH-O 2.88Å; W290-F294 HydrophobicContact CB-CD2 4.11Å; W290-F294 HydrophobicContact CB-CE2 4.2Å; W290-F294 HydrophobicContact CD2-CE2 4.01Å; W290-F294 AromaticContact CE3-CD2 3.98Å; W290-F294 HydrophobicContact CE3-CD2 3.98Å; W290-F294 AromaticContact CE3-CE2 3.3Å; W290-F294 HydrophobicContact CE3-CE2 3.3Å; W290-F294 HydrophobicContact CE3-CZ 4.1Å; W290-F294 HydrophobicContact CG-CE2 4.42Å; W290-F294 AromaticContact CZ3-CE2 3.99Å; W290-F294 HydrophobicContact CZ3-CE2 3.99Å; W290-F294 HydrophobicContact CZ3-CZ 4.36Å; W290-F294 VanDerWaalsContact O-CD2 3.32Å; W290-F294 WeakPolarHBondContact O-CD2 3.48Å; W290-F294 PolarHBondContact O-N 3Å; W290-F294 VanDerWaalsContact O-N 3.17Å; L291-F294 PolarHBondContact O-N 3.49Å; F294-P298 WeakPolarHBondContact O-CD 3.44Å; F294-P298 VanDerWaalsContact O-CG 3.28Å; F294-P298 WeakPolarHBondContact O-CG 3.5Å
295	L	87.6	Confident	85.6	Confident	79 Å²	79	45.4 Å²	45.4	41%	0.414	26%	0.263	S	S	.	.	H	α-helix	trans	-83.3	-47	165.9	-70.2	173.6	0	0	0	111.3	L291 F293 I299	L291-L295 HydrophobicContact CD1-CD1 4.13Å; L291-L295 HydrophobicContact CD1-CG 4.1Å; L291-L295 HydrophobicContact CG-CD1 3.91Å; L291-L295 HydrophobicContact CG-CG 4.31Å; L291-L295 VanDerWaalsContact O-CG 3.29Å; L291-L295 WeakPolarHBondContact O-CG 3.38Å; L291-L295 PolarHBondContact O-N 3.07Å; F293-L295 PolarHBondContact O-N 2.93Å; L295-I299 WeakPolarHBondContact O-CB 3.25Å; L295-I299 WeakPolarHBondContact O-CD1 3.36Å; L295-I299 WeakPolarHBondContact O-CG1 3.3Å; L295-I299 PolarHBondContact O-N 2.98Å
296	V	87.4	Confident	85.2	Confident	20 Å²	20	52.4 Å²	52.4	12%	0.121	29%	0.286	C	S	.	.	H	α-helix	trans	-65.1	-42	-177.5	164.3	0	0	0	0	112.3	P292 F293 I299 G300 P308 V312 F313 T316	P292-V296 WeakPolarHBondContact O-CG2 3.15Å; P292-V296 PolarHBondContact O-N 3.36Å; P292-V296 VanDerWaalsContact O-N 3.12Å; F293-V296 PolarHBondContact O-N 3.21Å; V296-I299 PolarHBondContact O-N 3.44Å; V296-G300 PolarHBondContact O-N 2.98Å; V296-P308 HydrophobicContact CG1-CB 4.29Å; V296-P308 HydrophobicContact CG1-CG 3.99Å; V296-P308 HydrophobicContact CG2-CG 4.35Å; V296-V312 HydrophobicContact CG2-CG1 4.29Å; V296-F313 HydrophobicContact CG1-CD2 3.95Å; V296-T316 HydrophobicContact CG2-CG2 4.31Å
297	L	84.8	Confident	84.7	Confident	13 Å²	13	57.6 Å²	57.6	7%	0.068	31%	0.305	C	S	.	.	H	α-helix	trans	-61.3	-53.3	-174.9	177.9	80.2	0	0	0	112.8	F293 I299 S301 F313	F293-L297 HydrophobicContact CE1-CD2 4.21Å; F293-L297 HydrophobicContact CZ-CB 4.43Å; F293-L297 HydrophobicContact CZ-CD1 4.35Å; F293-L297 HydrophobicContact CZ-CD2 4.24Å; F293-L297 WeakPolarHBondContact O-CB 3.41Å; F293-L297 PolarHBondContact O-N 2.81Å; L297-I299 PolarHBondContact O-N 3.01Å; L297-S301 WeakPolarHBondContact O-CB 3.48Å; L297-S301 PolarHBondContact O-N 2.82Å; L297-F313 HydrophobicContact CD1-CE2 4.16Å
298	P	83.4	Confident	84.4	Confident	15 Å²	15	57.8 Å²	57.8	10%	0.097	31%	0.307	C	S	.	.	H	α-helix	trans	-68.5	-33.1	176.9	-19.7	34	0	0	0	113.2	A196 F294 S301 I302	A196-P298 HydrophobicContact CB-CG 4.24Å; F294-P298 WeakPolarHBondContact O-CD 3.44Å; F294-P298 VanDerWaalsContact O-CG 3.28Å; F294-P298 WeakPolarHBondContact O-CG 3.5Å; P298-S301 PolarHBondContact O-N 3.44Å; P298-I302 HydrophobicContact CB-CD1 4.32Å; P298-I302 WeakPolarHBondContact O-CB 3.28Å; P298-I302 VanDerWaalsContact O-CG1 3.26Å; P298-I302 WeakPolarHBondContact O-CG1 3.41Å; P298-I302 PolarHBondContact O-N 2.78Å
299	I	84.8	Confident	84.2	Confident	74 Å²	74	55 Å²	55	38%	0.379	30%	0.298	S	S	.	.	H	α-helix	trans	-63.4	-46.5	177.7	-70.4	170.1	0	0	0	110.5	L295 V296 L297 S301 F303	L295-I299 WeakPolarHBondContact O-CB 3.25Å; L295-I299 WeakPolarHBondContact O-CD1 3.36Å; L295-I299 WeakPolarHBondContact O-CG1 3.3Å; L295-I299 PolarHBondContact O-N 2.98Å; V296-I299 PolarHBondContact O-N 3.44Å; L297-I299 PolarHBondContact O-N 3.01Å; I299-S301 PolarHBondContact O-N 3.35Å; I299-F303 WeakPolarHBondContact O-CA 3.37Å; I299-F303 PolarHBondContact O-N 3.15Å
300	G	79.9	Confident	83.8	Confident	11 Å²	11	59.5 Å²	59.5	11%	0.113	32%	0.322	C	S	.	.	H	α-helix	trans	-63.6	-31.8	177.2	0	0	0	0	0	113.2	V296	V296-G300 PolarHBondContact O-N 2.98Å
301	S	79.6	Confident	83.6	Confident	17 Å²	17	63.5 Å²	63.5	12%	0.119	35%	0.347	C	S	.	.	H	α-helix	trans	-78.9	-43.2	179.8	179.3	0	0	0	0	113.6	E187 P189 L297 P298 I299	E187-S301 WeakPolarHBondContact O-CB 3.29Å; E187-S301 PolarHBondContact O-OG 3.06Å; P189-S301 WeakPolarHBondContact CA-OG 3.49Å; L297-S301 WeakPolarHBondContact O-CB 3.48Å; L297-S301 PolarHBondContact O-N 2.82Å; P298-S301 PolarHBondContact O-N 3.44Å; I299-S301 PolarHBondContact O-N 3.35Å
302	I	81.9	Confident	83.5	Confident	78 Å²	78	63.5 Å²	63.5	40%	0.4	35%	0.35	S	S	.	.	H	α-helix	trans	-82.5	-35.6	-177.2	-61.5	166.8	0	0	0	111.5	I193 P298 P304	I193-I302 HydrophobicContact CD1-CD1 3.89Å; I193-I302 HydrophobicContact CD1-CG1 4.12Å; I193-I302 HydrophobicContact CG1-CD1 4.19Å; P298-I302 HydrophobicContact CB-CD1 4.32Å; P298-I302 WeakPolarHBondContact O-CB 3.28Å; P298-I302 VanDerWaalsContact O-CG1 3.26Å; P298-I302 WeakPolarHBondContact O-CG1 3.41Å; P298-I302 PolarHBondContact O-N 2.78Å; I302-P304 WeakPolarHBondContact O-CD 3.37Å
303	F	83.6	Confident	83.2	Confident	114 Å²	114	63.8 Å²	63.8	50%	0.5	35%	0.347	S	S	.	.			trans	-122.6	81.5	-176.1	-58	-75.7	0	0	0	111.4	I299 A305 Y306	I299-F303 WeakPolarHBondContact O-CA 3.37Å; I299-F303 PolarHBondContact O-N 3.15Å; F303-A305 PolarHBondContact O-N 3.11Å; F303-Y306 HydrophobicContact CB-CD2 4.07Å; F303-Y306 PolarHBondContact O-N 2.81Å
304	P	76.8	Confident	83.1	Confident	101 Å²	101	66.2 Å²	66.2	66%	0.656	36%	0.357	S	S	*	.	G	3₁₀ helix	trans	-56	-29.4	179.3	-26	34	0	0	0	113.7	I302 Y306 R307	I302-P304 WeakPolarHBondContact O-CD 3.37Å; P304-Y306 VanDerWaalsContact C-N 3.29Å; P304-Y306 PolarHBondContact O-N 3.43Å; P304-R307 PolarHBondContact O-N 2.88Å
305	A	75.9	Confident	83.2	Confident	95 Å²	95	70.8 Å²	70.8	79%	0.785	38%	0.381	S	S	*	.	G	3₁₀ helix	trans	-68.9	-22	178.5	0	0	0	0	0	114.3	F303	F303-A305 PolarHBondContact O-N 3.11Å
306	Y	79.3	Confident	83.3	Confident	182 Å²	182	67.6 Å²	67.6	71%	0.714	37%	0.365	S	S	*	.	G	3₁₀ helix	trans	-112.1	23.7	180	-63.3	-78.9	0	0	0	112	F303 P304 P308	F303-Y306 HydrophobicContact CB-CD2 4.07Å; F303-Y306 PolarHBondContact O-N 2.81Å; P304-Y306 VanDerWaalsContact C-N 3.29Å; P304-Y306 PolarHBondContact O-N 3.43Å; Y306-P308 WeakPolarHBondContact O-CD 3.41Å; Y306-P308 VanDerWaalsContact O-N 3.14Å
307	R	77.2	Confident	83.4	Confident	109 Å²	109	67.8 Å²	67.8	41%	0.411	36%	0.364	S	S	.	.	P	Polyproline II helix	trans	-56.1	118.1	-180	-171.9	-179.1	179	116	11.6	109.9	E187 P304	E187-R307 IonicContact OE1-CZ 3.28Å; E187-R307 IonicContact OE1-NH1 2.77Å; E187-R307 IonicContact OE1-NH2 3.09Å; E187-R307 PolarHBondContact OE1-NH2 3.34Å; E187-R307 IonicContact OE2-CZ 2.8Å; E187-R307 VanDerWaalsContact OE2-CZ 3.28Å; E187-R307 IonicContact OE2-NH1 3.66Å; E187-R307 PolarHBondContact OE2-NH1 3.4Å; E187-R307 IonicContact OE2-NH2 3.16Å; E187-R307 PolarHBondContact OE2-NH2 3.3Å; E187-R307 VanDerWaalsContact OE2-NH2 3.11Å; P304-R307 PolarHBondContact O-N 2.88Å
308	P	81.6	Confident	83.6	Confident	37 Å²	37	69.2 Å²	69.2	24%	0.24	37%	0.369	C	S	.	.	P	Polyproline II helix	trans	-60.7	154.2	174.7	-25.1	37.9	0	0	0	110.9	V296 Y306 V312	V296-P308 HydrophobicContact CG1-CB 4.29Å; V296-P308 HydrophobicContact CG1-CG 3.99Å; V296-P308 HydrophobicContact CG2-CG 4.35Å; Y306-P308 WeakPolarHBondContact O-CD 3.41Å; Y306-P308 VanDerWaalsContact O-N 3.14Å; P308-V312 HydrophobicContact CB-CB 4.24Å; P308-V312 HydrophobicContact CB-CG1 4.1Å
309	S	86.3	Confident	84	Confident	69 Å²	69	71.5 Å²	71.5	48%	0.483	38%	0.38	S	S	.	.	P	Polyproline II helix	trans	-61	150.7	178.5	64.5	0	0	0	0	111.7	T311 V312 F313	S309-T311 PolarHBondContact O-N 2.96Å; S309-T311 VanDerWaalsContact O-N 3.11Å; S309-V312 WeakPolarHBondContact O-CB 3.22Å; S309-V312 PolarHBondContact O-N 3.41Å; S309-V312 WeakPolarHBondContact OG-CG2 3.39Å; S309-F313 PolarHBondContact O-N 2.95Å; S309-F313 VanDerWaalsContact O-N 3.13Å
310	D	82	Confident	84.3	Confident	101 Å²	101	68 Å²	68	54%	0.54	36%	0.362	S	S	.	.	H	α-helix	trans	-56.5	-31.6	180	-66.1	-38.5	0	0	0	112.1	F313 K314	D310-F313 PolarHBondContact O-N 3.35Å; D310-K314 WeakPolarHBondContact O-CB 3.22Å; D310-K314 WeakPolarHBondContact O-CG 3.47Å; D310-K314 PolarHBondContact O-N 2.96Å
311	T	85.8	Confident	84.8	Confident	92 Å²	92	67.5 Å²	67.5	56%	0.564	36%	0.357	S	S	*	.	H	α-helix	trans	-62.5	-42.7	173.6	-51.6	0	0	0	0	112.2	S309 K314 I315	S309-T311 PolarHBondContact O-N 2.96Å; S309-T311 VanDerWaalsContact O-N 3.11Å; T311-K314 PolarHBondContact O-N 3.25Å; T311-I315 HydrophobicContact CG2-CD1 3.92Å; T311-I315 WeakPolarHBondContact O-CB 3.45Å; T311-I315 VanDerWaalsContact O-CG1 3.24Å; T311-I315 WeakPolarHBondContact O-CG1 3.42Å; T311-I315 PolarHBondContact O-N 3.43Å
312	V	87.8	Confident	85.3	Confident	59 Å²	59	71.2 Å²	71.2	36%	0.358	37%	0.371	S	S	.	.	H	α-helix	trans	-65.9	-43	177.7	172.2	0	0	0	0	110	V296 P308 S309 K314 I315 T316	V296-V312 HydrophobicContact CG2-CG1 4.29Å; P308-V312 HydrophobicContact CB-CB 4.24Å; P308-V312 HydrophobicContact CB-CG1 4.1Å; S309-V312 WeakPolarHBondContact O-CB 3.22Å; S309-V312 PolarHBondContact O-N 3.41Å; S309-V312 WeakPolarHBondContact OG-CG2 3.39Å; V312-K314 PolarHBondContact O-N 2.89Å; V312-I315 PolarHBondContact O-N 2.81Å; V312-T316 HydrophobicContact CG1-CG2 4.38Å; V312-T316 WeakPolarHBondContact O-CG2 3.17Å; V312-T316 PolarHBondContact O-N 2.87Å; V312-T316 PolarHBondContact O-OG1 2.88Å; V312-T316 VanDerWaalsContact O-OG1 3.13Å
313	F	86	Confident	85.7	Confident	48 Å²	48	67.5 Å²	67.5	21%	0.211	35%	0.352	C	S	.	.	H	α-helix	trans	-59.1	-47.6	175.6	-174.3	-87.8	0	0	0	111.7	F293 V296 L297 S309 D310 I315 T316 F317	F293-F313 HydrophobicContact CE2-CE1 4.49Å; F293-F313 AromaticContact CE2-CE2 3.91Å; F293-F313 HydrophobicContact CE2-CE2 3.91Å; F293-F313 AromaticContact CE2-CZ 3.81Å; F293-F313 HydrophobicContact CE2-CZ 3.81Å; F293-F313 HydrophobicContact CZ-CZ 4.49Å; V296-F313 HydrophobicContact CG1-CD2 3.95Å; L297-F313 HydrophobicContact CD1-CE2 4.16Å; S309-F313 PolarHBondContact O-N 2.95Å; S309-F313 VanDerWaalsContact O-N 3.13Å; D310-F313 PolarHBondContact O-N 3.35Å; F313-I315 PolarHBondContact O-N 2.95Å; F313-T316 PolarHBondContact O-N 2.94Å; F313-T316 PolarHBondContact O-OG1 3.26Å; F313-T316 VanDerWaalsContact O-OG1 3.07Å; F313-F317 WeakPolarHBondContact O-CB 3.29Å; F313-F317 PolarHBondContact O-N 3.09Å
314	K	86.3	Confident	85.9	Confident	64 Å²	64	62.1 Å²	62.1	28%	0.278	33%	0.329	S	S	.	.	H	α-helix	trans	-60.3	-45.3	176.7	-73.9	178.5	172.3	-161.7	0	112	E94 D97 D310 T311 V312 F317 W318	E94-K314 WeakPolarHBondContact OE1-CD 3.42Å; E94-K314 WeakPolarHBondContact OE1-CE 3.47Å; E94-K314 IonicContact OE1-NZ 3.77Å; E94-K314 PolarHBondContact OE1-NZ 3.28Å; E94-K314 VanDerWaalsContact OE2-CE 3.3Å; E94-K314 WeakPolarHBondContact OE2-CE 2.99Å; E94-K314 IonicContact OE2-NZ 3.35Å; E94-K314 PolarHBondContact OE2-NZ 3.44Å; D97-K314 IonicContact OD1-NZ 3.94Å; D310-K314 WeakPolarHBondContact O-CB 3.22Å; D310-K314 WeakPolarHBondContact O-CG 3.47Å; D310-K314 PolarHBondContact O-N 2.96Å; T311-K314 PolarHBondContact O-N 3.25Å; V312-K314 PolarHBondContact O-N 2.89Å; K314-F317 PolarHBondContact O-N 2.92Å; K314-W318 PolarHBondContact O-N 3.41Å
315	I	89.1	Confident	86.4	Confident	109 Å²	109	57.4 Å²	57.4	56%	0.559	30%	0.298	S	S	*	.	H	α-helix	trans	-61.8	-48	179.3	-71.1	167.5	0	0	0	111	T311 V312 F313 F317 L319	T311-I315 HydrophobicContact CG2-CD1 3.92Å; T311-I315 WeakPolarHBondContact O-CB 3.45Å; T311-I315 VanDerWaalsContact O-CG1 3.24Å; T311-I315 WeakPolarHBondContact O-CG1 3.42Å; T311-I315 PolarHBondContact O-N 3.43Å; V312-I315 PolarHBondContact O-N 2.81Å; F313-I315 PolarHBondContact O-N 2.95Å; I315-F317 VanDerWaalsContact C-N 3.32Å; I315-F317 PolarHBondContact O-N 3.1Å; I315-L319 VanDerWaalsContact O-CB 3.22Å; I315-L319 WeakPolarHBondContact O-CB 3.13Å; I315-L319 PolarHBondContact O-N 3.36Å
316	T	89.9	Confident	87.1	Confident	12 Å²	12	53.9 Å²	53.9	7%	0.074	27%	0.265	C	S	.	.	H	α-helix	trans	-68.2	-34.4	-179.4	58.2	0	0	0	0	112	P292 V296 V312 F313 L319 G320	P292-T316 HydrophobicContact CB-CG2 3.58Å; V296-T316 HydrophobicContact CG2-CG2 4.31Å; V312-T316 HydrophobicContact CG1-CG2 4.38Å; V312-T316 WeakPolarHBondContact O-CG2 3.17Å; V312-T316 PolarHBondContact O-N 2.87Å; V312-T316 PolarHBondContact O-OG1 2.88Å; V312-T316 VanDerWaalsContact O-OG1 3.13Å; F313-T316 PolarHBondContact O-N 2.94Å; F313-T316 PolarHBondContact O-OG1 3.26Å; F313-T316 VanDerWaalsContact O-OG1 3.07Å; T316-L319 PolarHBondContact O-N 2.95Å; T316-G320 PolarHBondContact O-N 3.44Å; T316-G320 VanDerWaalsContact O-N 3.09Å
317	F	88.8	Confident	87.4	Confident	23 Å²	23	45.2 Å²	45.2	10%	0.101	23%	0.232	C	C	.	.	H	α-helix	trans	-63.9	-51.9	175	-171.4	-111.4	0	0	0	112.3	I185 F293 F313 K314 I315 L319 G320 Y321	I185-F317 HydrophobicContact CD1-CD2 4.48Å; I185-F317 HydrophobicContact CD1-CE2 3.47Å; I185-F317 VanDerWaalsContact CD1-CE2 3.47Å; I185-F317 HydrophobicContact CD1-CZ 3.82Å; F293-F317 HydrophobicContact CD2-CB 4.2Å; F293-F317 HydrophobicContact CD2-CD2 4.03Å; F293-F317 HydrophobicContact CE2-CB 4.28Å; F293-F317 AromaticContact CE2-CD2 3.49Å; F293-F317 HydrophobicContact CE2-CD2 3.49Å; F293-F317 VanDerWaalsContact CE2-CD2 3.49Å; F293-F317 HydrophobicContact CE2-CE2 4.29Å; F293-F317 HydrophobicContact CE2-CG 4.37Å; F293-F317 AromaticContact CZ-CD2 3.83Å; F293-F317 HydrophobicContact CZ-CD2 3.83Å; F293-F317 HydrophobicContact CZ-CE2 4.22Å; F313-F317 WeakPolarHBondContact O-CB 3.29Å; F313-F317 PolarHBondContact O-N 3.09Å; K314-F317 PolarHBondContact O-N 2.92Å; I315-F317 VanDerWaalsContact C-N 3.32Å; I315-F317 PolarHBondContact O-N 3.1Å; F317-L319 VanDerWaalsContact C-N 3.28Å; F317-L319 PolarHBondContact O-N 3.47Å; F317-G320 PolarHBondContact O-N 2.91Å; F317-G320 VanDerWaalsContact O-N 3.1Å; F317-Y321 HydrophobicContact CD1-CD2 4.3Å; F317-Y321 AromaticContact CD1-CE2 3.75Å; F317-Y321 HydrophobicContact CD1-CE2 3.75Å; F317-Y321 HydrophobicContact CE1-CD2 4.2Å; F317-Y321 AromaticContact CE1-CE2 3.22Å; F317-Y321 HydrophobicContact CE1-CE2 3.22Å; F317-Y321 AromaticContact CE1-CZ 3.49Å; F317-Y321 VanDerWaalsContact CE1-CZ 3.49Å; F317-Y321 WeakPolarHBondContact CE1-OH 3.1Å; F317-Y321 HydrophobicContact CE2-CE2 4.48Å; F317-Y321 HydrophobicContact CZ-CE1 4.29Å; F317-Y321 AromaticContact CZ-CE2 3.68Å; F317-Y321 HydrophobicContact CZ-CE2 3.68Å; F317-Y321 AromaticContact CZ-CZ 3.38Å; F317-Y321 WeakPolarHBondContact CZ-OH 3.38Å; F317-Y321 PolarHBondContact O-N 3.49Å
318	W	90.8	Very high	87.9	Confident	43 Å²	43	40.4 Å²	40.4	16%	0.163	21%	0.214	C	C	.	.	H	α-helix	trans	-65.6	-30.7	176.9	-79.5	106	0	0	0	112.8	L40 F43 L87 A91 E94 K314 G320 Y321 F322	L40-W318 HydrophobicContact CD1-CH2 4.06Å; L40-W318 HydrophobicContact CD1-CZ2 3.93Å; L40-W318 HydrophobicContact CD2-CD2 4.21Å; L40-W318 HydrophobicContact CD2-CE3 3.91Å; L40-W318 HydrophobicContact CD2-CH2 3.54Å; L40-W318 HydrophobicContact CD2-CZ2 3.83Å; L40-W318 HydrophobicContact CD2-CZ3 3.58Å; L40-W318 HydrophobicContact CG-CH2 4.33Å; F43-W318 HydrophobicContact CD1-CE3 4.4Å; F43-W318 HydrophobicContact CD1-CZ3 4.02Å; F43-W318 HydrophobicContact CE1-CE3 4.08Å; F43-W318 AromaticContact CE1-CZ3 3.92Å; F43-W318 HydrophobicContact CE1-CZ3 3.92Å; L87-W318 HydrophobicContact CD2-CZ3 4.31Å; A91-W318 HydrophobicContact CB-CH2 4.3Å; E94-W318 HydrophobicContact CB-CZ2 4.42Å; K314-W318 PolarHBondContact O-N 3.41Å; W318-G320 VanDerWaalsContact C-N 3.34Å; W318-Y321 HydrophobicContact CD2-CD2 4.35Å; W318-Y321 AromaticContact CE3-CD2 3.89Å; W318-Y321 HydrophobicContact CE3-CD2 3.89Å; W318-Y321 HydrophobicContact CZ3-CD2 4.1Å; W318-Y321 PolarHBondContact O-N 3.35Å; W318-F322 PolarHBondContact O-N 3.21Å
319	L	91.6	Very high	88.2	Confident	63 Å²	63	42.3 Å²	42.3	33%	0.33	22%	0.222	S	C	.	.	H	α-helix	trans	-63.7	-38.8	172.2	-177.8	65.4	0	0	0	111.8	C289 P292 I315 T316 F317 F322	C289-L319 WeakPolarHBondContact CB-O 3.33Å; P292-L319 HydrophobicContact CB-CD2 4.46Å; P292-L319 HydrophobicContact CG-CD2 3.93Å; I315-L319 VanDerWaalsContact O-CB 3.22Å; I315-L319 WeakPolarHBondContact O-CB 3.13Å; I315-L319 PolarHBondContact O-N 3.36Å; T316-L319 PolarHBondContact O-N 2.95Å; F317-L319 VanDerWaalsContact C-N 3.28Å; F317-L319 PolarHBondContact O-N 3.47Å; L319-F322 WeakPolarHBondContact O-CB 3.19Å; L319-F322 PolarHBondContact O-N 3.17Å
320	G	90.3	Very high	88.2	Confident	0 Å²	0	39.7 Å²	39.7	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-59.8	-45.5	172.4	0	0	0	0	0	111.9	C289 W290 T316 F317 W318 F322 N323	C289-G320 PolarHBondContact O-N 3.26Å; W290-G320 WeakPolarHBondContact CZ2-O 3.27Å; W290-G320 PolarHBondContact NE1-O 3.33Å; T316-G320 PolarHBondContact O-N 3.44Å; T316-G320 VanDerWaalsContact O-N 3.09Å; F317-G320 PolarHBondContact O-N 2.91Å; F317-G320 VanDerWaalsContact O-N 3.1Å; W318-G320 VanDerWaalsContact C-N 3.34Å; G320-F322 VanDerWaalsContact C-N 3.29Å; G320-F322 PolarHBondContact O-N 3.25Å; G320-N323 WeakPolarHBondContact O-CB 2.98Å; G320-N323 PolarHBondContact O-N 3.22Å; G320-N323 VanDerWaalsContact O-N 3.17Å
321	Y	91.3	Very high	88.3	Confident	1 Å²	1	35.5 Å²	35.5	0%	0.004	18%	0.179	C	C	.	.	H	α-helix	trans	-63.1	-32.6	176.3	-68.3	-22.5	0	0	0	114	L82 V86 L87 D113 F317 W318 N323 S324	L82-Y321 HydrophobicContact CD1-CD1 4.3Å; L82-Y321 HydrophobicContact CD1-CE1 3.88Å; L82-Y321 HydrophobicContact CD2-CD1 4.07Å; L82-Y321 HydrophobicContact CD2-CE1 4.45Å; V86-Y321 VanDerWaalsContact CG1-OH 3.31Å; V86-Y321 WeakPolarHBondContact CG1-OH 3.32Å; L87-Y321 HydrophobicContact CD2-CD1 3.95Å; L87-Y321 HydrophobicContact CD2-CD2 3.23Å; L87-Y321 HydrophobicContact CD2-CE1 4.29Å; L87-Y321 HydrophobicContact CD2-CE2 3.6Å; L87-Y321 HydrophobicContact CD2-CG 3.39Å; D113-Y321 VanDerWaalsContact OD1-CE1 3.27Å; D113-Y321 WeakPolarHBondContact OD1-CE1 3.28Å; D113-Y321 PolarHBondContact OD1-OH 2.93Å; D113-Y321 PolarHBondContact OD2-OH 2.68Å; F317-Y321 HydrophobicContact CD1-CD2 4.3Å; F317-Y321 AromaticContact CD1-CE2 3.75Å; F317-Y321 HydrophobicContact CD1-CE2 3.75Å; F317-Y321 HydrophobicContact CE1-CD2 4.2Å; F317-Y321 AromaticContact CE1-CE2 3.22Å; F317-Y321 HydrophobicContact CE1-CE2 3.22Å; F317-Y321 AromaticContact CE1-CZ 3.49Å; F317-Y321 VanDerWaalsContact CE1-CZ 3.49Å; F317-Y321 WeakPolarHBondContact CE1-OH 3.1Å; F317-Y321 HydrophobicContact CE2-CE2 4.48Å; F317-Y321 HydrophobicContact CZ-CE1 4.29Å; F317-Y321 AromaticContact CZ-CE2 3.68Å; F317-Y321 HydrophobicContact CZ-CE2 3.68Å; F317-Y321 AromaticContact CZ-CZ 3.38Å; F317-Y321 WeakPolarHBondContact CZ-OH 3.38Å; F317-Y321 PolarHBondContact O-N 3.49Å; W318-Y321 HydrophobicContact CD2-CD2 4.35Å; W318-Y321 AromaticContact CE3-CD2 3.89Å; W318-Y321 HydrophobicContact CE3-CD2 3.89Å; W318-Y321 HydrophobicContact CZ3-CD2 4.1Å; W318-Y321 PolarHBondContact O-N 3.35Å; Y321-N323 PolarHBondContact O-N 3.02Å; Y321-N323 VanDerWaalsContact O-N 3.11Å; Y321-S324 WeakPolarHBondContact O-CB 3.43Å; Y321-S324 PolarHBondContact O-N 3.17Å; Y321-S324 VanDerWaalsContact O-N 3.08Å; Y321-S324 PolarHBondContact O-OG 2.95Å
322	F	89.9	Confident	88.2	Confident	95 Å²	95	32.2 Å²	32.2	42%	0.417	16%	0.159	S	C	.	.	H	α-helix	trans	-57.5	-26.7	176.7	-174.3	-110.5	0	0	0	112.7	F43 W318 L319 G320 S324 C325 I326	F43-F322 HydrophobicContact CD2-CD2 4.36Å; F43-F322 HydrophobicContact CE2-CB 4.32Å; F43-F322 AromaticContact CE2-CD2 3.71Å; F43-F322 HydrophobicContact CE2-CD2 3.71Å; F43-F322 HydrophobicContact CE2-CG 4.49Å; F43-F322 HydrophobicContact CZ-CB 4.48Å; W318-F322 PolarHBondContact O-N 3.21Å; L319-F322 WeakPolarHBondContact O-CB 3.19Å; L319-F322 PolarHBondContact O-N 3.17Å; G320-F322 VanDerWaalsContact C-N 3.29Å; G320-F322 PolarHBondContact O-N 3.25Å; F322-S324 VanDerWaalsContact C-N 3.26Å; F322-S324 PolarHBondContact O-N 3.06Å; F322-C325 WeakPolarHBondContact O-CB 3.17Å; F322-C325 PolarHBondContact O-N 3.18Å; F322-I326 HydrophobicContact CD1-CD1 3.51Å; F322-I326 HydrophobicContact CD1-CG1 3.71Å; F322-I326 HydrophobicContact CE1-CD1 3.49Å; F322-I326 VanDerWaalsContact CE1-CD1 3.49Å; F322-I326 HydrophobicContact CE1-CG1 3.44Å; F322-I326 VanDerWaalsContact CE1-CG1 3.44Å; F322-I326 HydrophobicContact CG-CG1 4.48Å; F322-I326 HydrophobicContact CZ-CG1 4.02Å; F322-I326 WeakPolarHBondContact O-CG1 3.39Å; F322-I326 PolarHBondContact O-N 3.13Å; F322-I326 VanDerWaalsContact O-N 3.13Å
323	N	89.3	Confident	87.8	Confident	1 Å²	1	34.6 Å²	34.6	1%	0.005	18%	0.177	C	C	.	.	H	α-helix	trans	-52.9	-40.3	174.1	-175	67.6	0	0	0	113.4	F286 C289 W290 G320 Y321 C325 I326 N327	F286-N323 WeakPolarHBondContact CA-OD1 3.4Å; C289-N323 HydrophobicContact CB-CB 3.96Å; W290-N323 PolarHBondContact NE1-ND2 3.37Å; G320-N323 WeakPolarHBondContact O-CB 2.98Å; G320-N323 PolarHBondContact O-N 3.22Å; G320-N323 VanDerWaalsContact O-N 3.17Å; Y321-N323 PolarHBondContact O-N 3.02Å; Y321-N323 VanDerWaalsContact O-N 3.11Å; N323-C325 PolarHBondContact O-N 3.22Å; N323-I326 PolarHBondContact O-N 2.61Å; N323-N327 PolarHBondContact O-N 2.73Å
324	S	88.3	Confident	87.2	Confident	1 Å²	1	33.4 Å²	33.4	1%	0.007	18%	0.175	C	C	.	.	H	α-helix	trans	-64	-27	179.7	67.2	0	0	0	0	113.3	N51 D79 Y321 F322 P328	N51-S324 PolarHBondContact ND2-O 3.45Å; D79-S324 WeakPolarHBondContact OD1-CB 3.27Å; Y321-S324 WeakPolarHBondContact O-CB 3.43Å; Y321-S324 PolarHBondContact O-N 3.17Å; Y321-S324 VanDerWaalsContact O-N 3.08Å; Y321-S324 PolarHBondContact O-OG 2.95Å; F322-S324 VanDerWaalsContact C-N 3.26Å; F322-S324 PolarHBondContact O-N 3.06Å; S324-P328 VanDerWaalsContact O-CD 3.29Å; S324-P328 WeakPolarHBondContact O-CD 3.27Å
325	C	87.7	Confident	86.7	Confident	1 Å²	1	32.9 Å²	32.9	1%	0.007	18%	0.175	C	C	.	.	H	α-helix	trans	-87.2	-28.8	178.3	-69.8	0	0	0	0	112.2	F43 F46 G47 F322 N323 N327 P328	F43-C325 HydrophobicContact CE2-CB 3.9Å; F43-C325 WeakPolarHBondContact CE2-SG 3.48Å; F46-C325 HydrophobicContact CD1-CB 3.84Å; F46-C325 HydrophobicContact CE1-CB 4.05Å; F46-C325 WeakPolarHBondContact CE1-O 3.36Å; G47-C325 VanDerWaalsContact CA-SG 3.6Å; F322-C325 WeakPolarHBondContact O-CB 3.17Å; F322-C325 PolarHBondContact O-N 3.18Å; N323-C325 PolarHBondContact O-N 3.22Å; C325-N327 VanDerWaalsContact C-N 3.3Å; C325-N327 PolarHBondContact O-N 3.22Å; C325-P328 WeakPolarHBondContact O-CD 3.35Å
326	I	89.3	Confident	86.1	Confident	21 Å²	21	33.2 Å²	33.2	11%	0.108	17%	0.174	C	C	.	.	H	α-helix	trans	-64.8	-37.6	176.1	-67.8	175.7	0	0	0	110.8	C285 C289 F322 N323 I329 I330	C285-I326 HydrophobicContact CB-CD1 4.26Å; C285-I326 HydrophobicContact CB-CG2 4.11Å; C289-I326 VanDerWaalsContact SG-CD1 3.51Å; F322-I326 HydrophobicContact CD1-CD1 3.51Å; F322-I326 HydrophobicContact CD1-CG1 3.71Å; F322-I326 HydrophobicContact CE1-CD1 3.49Å; F322-I326 VanDerWaalsContact CE1-CD1 3.49Å; F322-I326 HydrophobicContact CE1-CG1 3.44Å; F322-I326 VanDerWaalsContact CE1-CG1 3.44Å; F322-I326 HydrophobicContact CG-CG1 4.48Å; F322-I326 HydrophobicContact CZ-CG1 4.02Å; F322-I326 WeakPolarHBondContact O-CG1 3.39Å; F322-I326 PolarHBondContact O-N 3.13Å; F322-I326 VanDerWaalsContact O-N 3.13Å; N323-I326 PolarHBondContact O-N 2.61Å; I326-I329 WeakPolarHBondContact O-CA 3.5Å; I326-I329 WeakPolarHBondContact O-CB 3.45Å; I326-I329 PolarHBondContact O-N 3.08Å; I326-I330 HydrophobicContact CG2-CD1 3.27Å; I326-I330 HydrophobicContact CG2-CG1 3.57Å; I326-I330 WeakPolarHBondContact O-CG1 3.33Å; I326-I330 PolarHBondContact O-N 3.44Å
327	N	86	Confident	85.6	Confident	1 Å²	1	35.7 Å²	35.7	1%	0.005	19%	0.185	C	C	.	.	H	α-helix	trans	-55.5	-52.2	-173.9	-71.5	-27	0	0	0	113.4	D79 N323 C325 I329 I330 Y331	D79-N327 PolarHBondContact OD2-ND2 3.49Å; N323-N327 PolarHBondContact O-N 2.73Å; C325-N327 VanDerWaalsContact C-N 3.3Å; C325-N327 PolarHBondContact O-N 3.22Å; N327-I329 PolarHBondContact O-N 3.44Å; N327-I329 VanDerWaalsContact O-N 3.17Å; N327-I330 PolarHBondContact O-N 3.49Å; N327-Y331 HydrophobicContact CB-CE2 4.11Å; N327-Y331 WeakPolarHBondContact O-CD2 3.48Å; N327-Y331 WeakPolarHBondContact O-CE2 3.48Å; N327-Y331 PolarHBondContact O-N 2.93Å
328	P	87.9	Confident	85.2	Confident	7 Å²	7	34.8 Å²	34.8	5%	0.045	18%	0.181	C	C	.	.	H	α-helix	trans	-58.4	-22.8	173.1	-27.8	35	0	0	0	116	G50 V54 S324 C325 P332	G50-P328 VanDerWaalsContact C-CG 3.41Å; V54-P328 HydrophobicContact CG2-CB 4.13Å; V54-P328 HydrophobicContact CG2-CG 4.23Å; S324-P328 VanDerWaalsContact O-CD 3.29Å; S324-P328 WeakPolarHBondContact O-CD 3.27Å; C325-P328 WeakPolarHBondContact O-CD 3.35Å; P328-P332 WeakPolarHBondContact O-CD 3.36Å; P328-P332 WeakPolarHBondContact O-CG 3.4Å
329	I	88	Confident	84.9	Confident	78 Å²	78	37.8 Å²	37.8	40%	0.4	20%	0.195	S	C	.	.	H	α-helix	trans	-83.2	-41.1	176.8	-59.2	171.8	0	0	0	110.5	F46 I326 N327 Y331 P332 C333	F46-I329 HydrophobicContact CE1-CD1 3.78Å; F46-I329 HydrophobicContact CE1-CG1 3.94Å; F46-I329 HydrophobicContact CZ-CD1 3.65Å; F46-I329 HydrophobicContact CZ-CG1 3.57Å; I326-I329 WeakPolarHBondContact O-CA 3.5Å; I326-I329 WeakPolarHBondContact O-CB 3.45Å; I326-I329 PolarHBondContact O-N 3.08Å; N327-I329 PolarHBondContact O-N 3.44Å; N327-I329 VanDerWaalsContact O-N 3.17Å; I329-Y331 PolarHBondContact O-N 3.21Å; I329-P332 WeakPolarHBondContact O-CD 3.44Å; I329-C333 WeakPolarHBondContact O-CB 3.3Å; I329-C333 PolarHBondContact O-N 2.81Å; I329-C333 PolarHBondContact O-SG 2.84Å
330	I	86	Confident	84.5	Confident	14 Å²	14	40.3 Å²	40.3	7%	0.072	20%	0.204	C	C	.	.	H	α-helix	trans	-64.8	-44	-176.4	-65.1	178.3	0	0	0	110.5	I281 V282 C285 I326 N327 C333 S334	I281-I330 HydrophobicContact CG2-CD1 4.45Å; V282-I330 HydrophobicContact CB-CD1 4.36Å; V282-I330 HydrophobicContact CG2-CB 4.31Å; V282-I330 HydrophobicContact CG2-CD1 4Å; V282-I330 HydrophobicContact CG2-CG2 3.5Å; C285-I330 HydrophobicContact CB-CD1 4.24Å; I326-I330 HydrophobicContact CG2-CD1 3.27Å; I326-I330 HydrophobicContact CG2-CG1 3.57Å; I326-I330 WeakPolarHBondContact O-CG1 3.33Å; I326-I330 PolarHBondContact O-N 3.44Å; N327-I330 PolarHBondContact O-N 3.49Å; I330-C333 PolarHBondContact O-N 3.06Å; I330-S334 WeakPolarHBondContact O-CB 3.26Å; I330-S334 PolarHBondContact O-N 2.8Å; I330-S334 PolarHBondContact O-OG 3.27Å
331	Y	83.8	Confident	84.1	Confident	13 Å²	13	40.4 Å²	40.4	5%	0.051	20%	0.204	C	C	.	.	H	α-helix	trans	-61.9	-46.6	-172.4	-53.6	-48.4	0	0	0	113.9	V54 I72 L75 N327 I329 S334 N335	V54-Y331 HydrophobicContact CG1-CD2 4.14Å; V54-Y331 HydrophobicContact CG1-CE2 4.23Å; V54-Y331 HydrophobicContact CG2-CD2 3.91Å; V54-Y331 HydrophobicContact CG2-CE2 4.36Å; I72-Y331 HydrophobicContact CG2-CD2 4.11Å; I72-Y331 HydrophobicContact CG2-CE1 4.22Å; I72-Y331 HydrophobicContact CG2-CE2 3.67Å; L75-Y331 WeakPolarHBondContact CD2-OH 3.37Å; N327-Y331 HydrophobicContact CB-CE2 4.11Å; N327-Y331 WeakPolarHBondContact O-CD2 3.48Å; N327-Y331 WeakPolarHBondContact O-CE2 3.48Å; N327-Y331 PolarHBondContact O-N 2.93Å; I329-Y331 PolarHBondContact O-N 3.21Å; Y331-S334 PolarHBondContact O-N 3.49Å; Y331-S334 PolarHBondContact O-OG 2.95Å; Y331-N335 WeakPolarHBondContact O-CB 3.12Å; Y331-N335 PolarHBondContact O-N 2.88Å
332	P	83.2	Confident	83.8	Confident	23 Å²	23	41.3 Å²	41.3	15%	0.149	21%	0.208	C	C	.	.	H	α-helix	trans	-68.4	-35.7	175.3	-22.1	35.6	0	0	0	113.8	P328 I329 S334 K339 F342	P328-P332 WeakPolarHBondContact O-CD 3.36Å; P328-P332 WeakPolarHBondContact O-CG 3.4Å; I329-P332 WeakPolarHBondContact O-CD 3.44Å; P332-S334 PolarHBondContact O-N 2.88Å; P332-K339 HydrophobicContact CB-CB 4.49Å; P332-F342 HydrophobicContact CG-CD1 3.72Å; P332-F342 HydrophobicContact CG-CD2 4.13Å; P332-F342 HydrophobicContact CG-CE1 3.72Å; P332-F342 HydrophobicContact CG-CE2 4.13Å; P332-F342 HydrophobicContact CG-CG 3.93Å; P332-F342 HydrophobicContact CG-CZ 3.93Å
333	C	80.9	Confident	83.5	Confident	109 Å²	109	42.2 Å²	42.2	74%	0.736	21%	0.213	S	C	*	.	H	α-helix	trans	-67.1	-29.1	178.6	-72.5	0	0	0	0	112.4	I329 I330	I329-C333 WeakPolarHBondContact O-CB 3.3Å; I329-C333 PolarHBondContact O-N 2.81Å; I329-C333 PolarHBondContact O-SG 2.84Å; I330-C333 PolarHBondContact O-N 3.06Å
334	S	72	Confident	83.1	Confident	23 Å²	23	44.4 Å²	44.4	16%	0.161	23%	0.229	C	C	.	.	H	α-helix	trans	-103.8	-32.4	-169	68.5	0	0	0	0	113.5	T278 I330 Y331 P332	T278-S334 WeakPolarHBondContact CG2-OG 3.39Å; T278-S334 WeakPolarHBondContact OG1-CB 3.35Å; I330-S334 WeakPolarHBondContact O-CB 3.26Å; I330-S334 PolarHBondContact O-N 2.8Å; I330-S334 PolarHBondContact O-OG 3.27Å; Y331-S334 PolarHBondContact O-N 3.49Å; Y331-S334 PolarHBondContact O-OG 2.95Å; P332-S334 PolarHBondContact O-N 2.88Å
335	N	76.2	Confident	82.8	Confident	53 Å²	53	45.7 Å²	45.7	28%	0.283	24%	0.236	S	C	.	.			trans	-119.5	114.1	179.1	-172.1	-12.1	0	0	0	111.3	Y331 E337 F338 K339	Y331-N335 WeakPolarHBondContact O-CB 3.12Å; Y331-N335 PolarHBondContact O-N 2.88Å; N335-E337 PolarHBondContact O-N 3.47Å; N335-E337 WeakPolarHBondContact OD1-CB 3.22Å; N335-E337 PolarHBondContact OD1-N 3.33Å; N335-F338 HydrophobicContact CB-CB 4.31Å; N335-F338 HydrophobicContact CB-CD2 3.88Å; N335-F338 PolarHBondContact O-N 3.5Å; N335-F338 VanDerWaalsContact O-N 3.11Å; N335-K339 PolarHBondContact O-N 2.92Å
336	Q	76.8	Confident	82.5	Confident	116 Å²	116	51.4 Å²	51.4	54%	0.542	27%	0.266	S	S	.	.	H	α-helix	trans	-60.7	-26.3	178.8	-70.7	-176.6	-12	0	0	113.1	K339 K340	Q336-K339 PolarHBondContact O-N 3.07Å; Q336-K340 VanDerWaalsContact O-CG 3.31Å; Q336-K340 WeakPolarHBondContact O-CG 3.22Å; Q336-K340 PolarHBondContact O-N 3.41Å
337	E	80.3	Confident	81.5	Confident	64 Å²	64	52.6 Å²	52.6	30%	0.299	28%	0.283	S	S	.	.	H	α-helix	trans	-71.7	-39.8	177.6	-60.5	-64.8	111.6	0	0	111.1	H63 L64 N335 K340 A341	H63-E337 IonicContact CE1-OE2 2.85Å; H63-E337 PolarHBondContact CE1-OE2 3.48Å; H63-E337 IonicContact ND1-OE2 3.27Å; H63-E337 PolarHBondContact ND1-OE2 3.39Å; L64-E337 HydrophobicContact CD2-CB 3.84Å; N335-E337 PolarHBondContact O-N 3.47Å; N335-E337 WeakPolarHBondContact OD1-CB 3.22Å; N335-E337 PolarHBondContact OD1-N 3.33Å; E337-K340 IonicContact OE1-NZ 3.17Å; E337-K340 PolarHBondContact OE1-NZ 3.13Å; E337-K340 VanDerWaalsContact OE1-NZ 3.09Å; E337-A341 WeakPolarHBondContact O-CB 3.48Å; E337-A341 PolarHBondContact O-N 3.13Å
338	F	80.3	Confident	80.2	Confident	3 Å²	3	57.9 Å²	57.9	1%	0.013	32%	0.315	C	S	.	.	H	α-helix	trans	-65.8	-41.8	170.4	-86.9	-73.3	0	0	0	111.5	S57 V58 L64 H69 I72 N335 K340 A341 F342	S57-F338 WeakPolarHBondContact OG-CD1 3.36Å; S57-F338 WeakPolarHBondContact OG-CE1 3.3Å; V58-F338 HydrophobicContact CG2-CE1 3.83Å; V58-F338 HydrophobicContact CG2-CZ 4.06Å; L64-F338 HydrophobicContact CD1-CD1 4.45Å; H69-F338 AromaticContact CD2-CE2 3.44Å; H69-F338 VanDerWaalsContact CD2-CE2 3.44Å; H69-F338 WeakPolarHBondContact CD2-CE2 3.42Å; H69-F338 AromaticContact CD2-CZ 3.44Å; H69-F338 VanDerWaalsContact CD2-CZ 3.44Å; H69-F338 WeakPolarHBondContact CD2-CZ 3.28Å; H69-F338 AromaticContact NE2-CE2 3.56Å; I72-F338 HydrophobicContact CD1-CE2 4.06Å; I72-F338 HydrophobicContact CD1-CZ 4.14Å; I72-F338 HydrophobicContact CG2-CZ 4.15Å; N335-F338 HydrophobicContact CB-CB 4.31Å; N335-F338 HydrophobicContact CB-CD2 3.88Å; N335-F338 PolarHBondContact O-N 3.5Å; N335-F338 VanDerWaalsContact O-N 3.11Å; F338-K340 PolarHBondContact O-N 3.39Å; F338-A341 PolarHBondContact O-N 2.96Å; F338-F342 HydrophobicContact CD1-CE2 4.2Å; F338-F342 WeakPolarHBondContact O-CB 3.24Å; F338-F342 VanDerWaalsContact O-CD2 3.23Å; F338-F342 WeakPolarHBondContact O-CD2 3.41Å; F338-F342 PolarHBondContact O-N 3.11Å
339	K	84.1	Confident	78.4	Confident	107 Å²	107	64.9 Å²	64.9	47%	0.465	35%	0.347	S	S	.	.	H	α-helix	trans	-55.6	-49	175.3	-172.2	176.5	177.6	175.9	0	112.2	P332 N335 Q336 A341 F342 Q343	P332-K339 HydrophobicContact CB-CB 4.49Å; N335-K339 PolarHBondContact O-N 2.92Å; Q336-K339 PolarHBondContact O-N 3.07Å; K339-A341 VanDerWaalsContact C-N 3.34Å; K339-A341 PolarHBondContact O-N 2.85Å; K339-F342 PolarHBondContact O-N 2.94Å; K339-Q343 WeakPolarHBondContact O-CB 3.21Å; K339-Q343 VanDerWaalsContact O-CG 3.29Å; K339-Q343 WeakPolarHBondContact O-CG 3.25Å; K339-Q343 PolarHBondContact O-N 3.38Å
340	K	83.6	Confident	76.4	Confident	116 Å²	116	65.3 Å²	65.3	50%	0.504	36%	0.356	S	S	.	.	H	α-helix	trans	-63.4	-40.7	177.6	-70.7	170.9	-169.7	163.9	0	111.7	Q336 E337 F338 Q343 S344	Q336-K340 VanDerWaalsContact O-CG 3.31Å; Q336-K340 WeakPolarHBondContact O-CG 3.22Å; Q336-K340 PolarHBondContact O-N 3.41Å; E337-K340 IonicContact OE1-NZ 3.17Å; E337-K340 PolarHBondContact OE1-NZ 3.13Å; E337-K340 VanDerWaalsContact OE1-NZ 3.09Å; F338-K340 PolarHBondContact O-N 3.39Å; K340-Q343 PolarHBondContact O-N 3.12Å; K340-S344 VanDerWaalsContact O-CB 3.28Å; K340-S344 WeakPolarHBondContact O-CB 3.49Å; K340-S344 PolarHBondContact O-N 3.31Å
341	A	82.2	Confident	74.5	Confident	1 Å²	1	72.5 Å²	72.5	1%	0.008	39%	0.394	C	S	.	.	H	α-helix	trans	-64	-43	177.2	0	0	0	0	0	111.9	L64 E337 F338 K339 S344 L345	L64-A341 HydrophobicContact CD1-CB 3.9Å; E337-A341 WeakPolarHBondContact O-CB 3.48Å; E337-A341 PolarHBondContact O-N 3.13Å; F338-A341 PolarHBondContact O-N 2.96Å; K339-A341 VanDerWaalsContact C-N 3.34Å; K339-A341 PolarHBondContact O-N 2.85Å; A341-S344 PolarHBondContact O-N 3.21Å; A341-L345 VanDerWaalsContact O-CG 3.3Å; A341-L345 WeakPolarHBondContact O-CG 3.37Å; A341-L345 PolarHBondContact O-N 2.86Å
342	F	83.8	Confident	72.3	Confident	20 Å²	20	82.2 Å²	82.2	9%	0.088	43%	0.43	C	S	.	.	H	α-helix	trans	-62.6	-46.1	174.9	-88.3	-123.9	0	0	0	111.5	L53 V54 P332 F338 K339 S344 L345 L346	L53-F342 HydrophobicContact CB-CD1 4.41Å; L53-F342 HydrophobicContact CB-CE1 3.82Å; L53-F342 HydrophobicContact CB-CZ 3.95Å; L53-F342 HydrophobicContact CD1-CE1 4.37Å; V54-F342 HydrophobicContact CG2-CE2 4.44Å; V54-F342 HydrophobicContact CG2-CZ 3.77Å; P332-F342 HydrophobicContact CG-CD1 3.72Å; P332-F342 HydrophobicContact CG-CD2 4.13Å; P332-F342 HydrophobicContact CG-CE1 3.72Å; P332-F342 HydrophobicContact CG-CE2 4.13Å; P332-F342 HydrophobicContact CG-CG 3.93Å; P332-F342 HydrophobicContact CG-CZ 3.93Å; F338-F342 HydrophobicContact CD1-CE2 4.2Å; F338-F342 WeakPolarHBondContact O-CB 3.24Å; F338-F342 VanDerWaalsContact O-CD2 3.23Å; F338-F342 WeakPolarHBondContact O-CD2 3.41Å; F338-F342 PolarHBondContact O-N 3.11Å; K339-F342 PolarHBondContact O-N 2.94Å; F342-S344 VanDerWaalsContact C-N 3.31Å; F342-S344 PolarHBondContact O-N 3.37Å; F342-L345 PolarHBondContact O-N 3.49Å; F342-L346 WeakPolarHBondContact O-CB 3.33Å; F342-L346 WeakPolarHBondContact O-CG 3.46Å; F342-L346 PolarHBondContact O-N 3.36Å
343	Q	83.3	Confident	70.2	Confident	114 Å²	114	90 Å²	90	53%	0.533	47%	0.467	S	S	.	.	H	α-helix	trans	-63.2	-35.4	176.7	-73.2	176.4	-29.1	0	0	112.6	K339 K340 G347	K339-Q343 WeakPolarHBondContact O-CB 3.21Å; K339-Q343 VanDerWaalsContact O-CG 3.29Å; K339-Q343 WeakPolarHBondContact O-CG 3.25Å; K339-Q343 PolarHBondContact O-N 3.38Å; K340-Q343 PolarHBondContact O-N 3.12Å; Q343-G347 VanDerWaalsContact O-CA 3.29Å; Q343-G347 WeakPolarHBondContact O-CA 3.27Å; Q343-G347 PolarHBondContact O-N 2.88Å
344	S	81.3	Confident	68.1	Low	48 Å²	48	89.9 Å²	89.9	34%	0.336	46%	0.463	S	S	.	.	H	α-helix	trans	-69.9	-36.8	175.5	-177	0	0	0	0	112.5	K340 A341 F342 G347	K340-S344 VanDerWaalsContact O-CB 3.28Å; K340-S344 WeakPolarHBondContact O-CB 3.49Å; K340-S344 PolarHBondContact O-N 3.31Å; A341-S344 PolarHBondContact O-N 3.21Å; F342-S344 VanDerWaalsContact C-N 3.31Å; F342-S344 PolarHBondContact O-N 3.37Å; S344-G347 CarbonylContact O-C 3.57Å
345	L	82	Confident	66.4	Low	27 Å²	27	94.3 Å²	94.3	14%	0.141	49%	0.491	C	S	.	.	H	α-helix	trans	-73.4	-41.7	177.4	-72.2	173.2	0	0	0	112.4	L56 C60 A341 F342	L56-L345 HydrophobicContact CB-CD1 3.9Å; C60-L345 HydrophobicContact CB-CD2 4.26Å; A341-L345 VanDerWaalsContact O-CG 3.3Å; A341-L345 WeakPolarHBondContact O-CG 3.37Å; A341-L345 PolarHBondContact O-N 2.86Å; F342-L345 PolarHBondContact O-N 3.49Å
346	L	81.4	Confident	64.4	Low	122 Å²	122	100.6 Å²	100.6	64%	0.639	51%	0.511	S	S	*	.	H	α-helix	trans	-73.6	-32.3	174.9	-67.2	167.4	0	0	0	111.6	L53 F342 V348	L53-L346 HydrophobicContact CD1-CD2 4.46Å; F342-L346 WeakPolarHBondContact O-CB 3.33Å; F342-L346 WeakPolarHBondContact O-CG 3.46Å; F342-L346 PolarHBondContact O-N 3.36Å; L346-V348 PolarHBondContact O-N 3.29Å
347	G	69	Low	62.5	Low	46 Å²	46	100.8 Å²	100.8	47%	0.474	52%	0.522	S	S	.	.	S	Bend	trans	-92.1	58.3	174.8	0	0	0	0	0	112.6	Q343 S344 H349	Q343-G347 VanDerWaalsContact O-CA 3.29Å; Q343-G347 WeakPolarHBondContact O-CA 3.27Å; Q343-G347 PolarHBondContact O-N 2.88Å; S344-G347 CarbonylContact O-C 3.57Å; G347-H349 PolarHBondContact O-N 2.84Å
348	V	57.4	Low	60.2	Low	112 Å²	112	106 Å²	106	68%	0.679	55%	0.546	S	S	*	.	S	Bend	trans	19.8	88	164.1	-168.3	0	0	0	0	115.7	L346	L346-V348 PolarHBondContact O-N 3.29Å
349	H	50.7	Low	57.9	Low	153 Å²	153	114.9 Å²	114.9	71%	0.708	59%	0.587	S	S	*	*			trans	-131.9	18.1	156.7	-102.6	77.6	0	0	0	113.1	G347 L351	G347-H349 PolarHBondContact O-N 2.84Å; H349-L351 VanDerWaalsContact C-N 3.32Å; H349-L351 PolarHBondContact O-N 3.22Å
350	C	46.4	Very low	55.4	Low	87 Å²	87	117.7 Å²	117.7	59%	0.588	60%	0.602	S	S	*	*	T	Hydrogen-bonded Turn	trans	-82.3	10.6	-176.8	-78.8	0	0	0	0	116
351	L	46	Very low	52.8	Low	166 Å²	166	121.1 Å²	121.1	87%	0.869	62%	0.619	S	S	*	*	T	Hydrogen-bonded Turn	trans	-95.7	13.7	175.4	-73.3	173.7	0	0	0	115	H349	H349-L351 VanDerWaalsContact C-N 3.32Å; H349-L351 PolarHBondContact O-N 3.22Å
352	R	38.8	Very low	50.4	Low	216 Å²	216	128.8 Å²	128.8	82%	0.815	66%	0.659	S	S	*	*			trans	-135.5	78	170.8	-104	-177.4	176.1	-178.6	-0.6	112.5	T354	R352-T354 VanDerWaalsContact C-N 3.27Å; R352-T354 PolarHBondContact O-N 3.34Å; R352-T354 VanDerWaalsContact O-N 3.16Å
353	M	37.3	Very low	47.8	Very low	187 Å²	187	133.1 Å²	133.1	92%	0.921	69%	0.692	S	S	*	*			trans	-68.9	94.1	142.8	-80.9	-125.6	-174.5	0	0	107	P355	M353-P355 WeakPolarHBondContact O-CD 3.43Å
354	T	37.7	Very low	45.2	Very low	106 Å²	106	134.1 Å²	134.1	65%	0.65	71%	0.706	S	S	*	*	P	Polyproline II helix	trans	-71.3	123.8	162.5	36.1	0	0	0	0	108.1	R352 R356	R352-T354 VanDerWaalsContact C-N 3.27Å; R352-T354 PolarHBondContact O-N 3.34Å; R352-T354 VanDerWaalsContact O-N 3.16Å; T354-R356 PolarHBondContact O-N 3.14Å
355	P	35.8	Very low	42.6	Very low	117 Å²	117	137.7 Å²	137.7	76%	0.76	73%	0.731	S	S	*	*	P	Polyproline II helix	trans	-62.1	136.5	169.5	-11.4	25.5	0	0	0	108.3	M353	M353-P355 WeakPolarHBondContact O-CD 3.43Å
356	R	34.8	Very low	40	Very low	185 Å²	185	145.6 Å²	145.6	70%	0.698	77%	0.767	S	S	*	*	P	Polyproline II helix	trans	-64.3	134.4	167.4	-71.6	178.3	178.1	167.2	1.8	108.2	T354 H358	T354-R356 PolarHBondContact O-N 3.14Å; R356-H358 PolarHBondContact O-N 2.97Å
357	P	35.8	Very low	37.3	Very low	119 Å²	119	145.7 Å²	145.7	77%	0.773	78%	0.778	S	S	*	*	P	Polyproline II helix	trans	-66.7	121.8	167	24.6	-26.6	0	0	0	108.8	H359	P357-H359 PolarHBondContact O-N 3.39Å
358	H	32	Very low	35.2	Very low	175 Å²	175	152.2 Å²	152.2	81%	0.81	80%	0.796	S	S	*	*	P	Polyproline II helix	trans	-65.2	119.5	168.3	-102.8	-84.8	0	0	0	108.7	R356 H360	R356-H358 PolarHBondContact O-N 2.97Å; H358-H360 PolarHBondContact O-N 3.43Å
359	H	33.1	Very low	33.6	Very low	188 Å²	188	153 Å²	153	87%	0.87	80%	0.802	S	S	*	*			trans	-74	106.5	161.4	-90.9	-71.3	0	0	0	108.1	P357	P357-H359 PolarHBondContact O-N 3.39Å
360	H	30.6	Very low	32.4	Very low	166 Å²	166	155 Å²	155	77%	0.769	81%	0.811	S	S	*	*			trans	-73.2	121	160.7	-89.8	-78.9	0	0	0	108.6	H358 L362	H358-H360 PolarHBondContact O-N 3.43Å; H360-L362 PolarHBondContact O-N 2.89Å
361	H	30.2	Very low	31.3	Very low	189 Å²	189	154.3 Å²	154.3	88%	0.875	82%	0.819	S	S	*	*			trans	-71	113.3	163.4	-127.5	-89.1	0	0	0	106.8
362	L	31.1	Very low	30.3	Very low	161 Å²	161	154.9 Å²	154.9	84%	0.843	82%	0.817	S	S	*	*			trans	-106.3	128.8	164.4	-135.5	85	0	0	0	108.4	H360	H360-L362 PolarHBondContact O-N 2.89Å
363	S	29.2	Very low	29.9	Very low	111 Å²	111	149.9 Å²	149.9	78%	0.776	82%	0.815	S	S	*	*			trans	-65	143	-175.9	-39.4	0	0	0	0	112.4
364	T	28.1	Very low	29.6	Very low	135 Å²	135	148.7 Å²	148.7	83%	0.828	81%	0.807	S	S	*	*			trans	-61.3	140.4	176.7	-10	0	0	0	0	112.7
365	S	27.5	Very low	29	Very low	124 Å²	124	146.6 Å²	146.6	87%	0.867	81%	0.806	S	S	*	*			trans	-142.5	133.3	149.8	-74	0	0	0	0	108.5
366	Q	27.8	Very low	28.4	Very low	193 Å²	193	149.7 Å²	149.7	90%	0.902	82%	0.816	S	S	*	*			trans	-76.5	146	-165.6	-66.9	169.3	-23.2	0	0	113.4
367	S	24.6	Very low	27.9	Very low	124 Å²	124	146.6 Å²	146.6	87%	0.867	82%	0.817	S	S	*	*			trans	-163.2	138.2	135	52.9	0	0	0	0	111
368	Q	24.5	Very low	27.4	Very low	182 Å²	182	149.2 Å²	149.2	85%	0.85	82%	0.824	S	S	*	*			trans	-61.5	148.4	-172.3	-64.6	162.9	-22.5	0	0	114.5
369	T	23.9	Very low	27	Very low	129 Å²	129	146.7 Å²	146.7	79%	0.791	83%	0.826	S	S	*	*				175.7	130.5	116.1	37.8	0	0	0	0	112.4
370	Q	24.2	Very low	26.8	Very low	196 Å²	196	146.1 Å²	146.1	92%	0.916	83%	0.828	S	S	*	*			trans	47.7	122.3	148.4	-73.1	177.5	-14.6	0	0	122
371	G	23.7	Very low	26.5	Very low	72 Å²	72	145.6 Å²	145.6	74%	0.742	83%	0.831	S	S	*	*			trans	112.4	118.5	130.1	0	0	0	0	0	118.5
372	H	25.3	Very low	26.4	Very low	178 Å²	178	140.9 Å²	140.9	82%	0.824	82%	0.82	S	S	*	*			trans	75.7	118	146.7	-94.1	42.7	0	0	0	121.4
373	S	31.1	Very low	26.2	Very low	111 Å²	111	144.9 Å²	144.9	78%	0.776	82%	0.823	S	S	*	*			trans	-55.4	136.9	158.8	-14.2	0	0	0	0	112.4
374	Q	30.5	Very low	26.3	Very low	161 Å²	161	143.2 Å²	143.2	75%	0.752	82%	0.824	S	S	*	*			trans	-171	128.4	157.5	-102.8	158.6	56.3	0	0	108.2
375	G	25.9	Very low	26.3	Very low	62 Å²	62	141.2 Å²	141.2	64%	0.639	82%	0.821	S	S	*	*			cis	91.2	118.9	24.8	0	0	0	0	0	109.9	T377	G375-T377 PolarHBondContact O-N 3.11Å
376	L	22.8	Very low	26.3	Very low	183 Å²	183	141.6 Å²	141.6	96%	0.958	82%	0.821	S	S	*	*			trans	-44.7	124.2	177.4	-114.2	84	0	0	0	112.3
377	T	23.7	Very low	26.3	Very low	120 Å²	120	138.1 Å²	138.1	74%	0.736	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-95.5	116.7	172	43.3	0	0	0	0	111.4	G375	G375-T377 PolarHBondContact O-N 3.11Å
378	L	24.8	Very low	26.4	Very low	174 Å²	174	144 Å²	144	91%	0.911	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-91.7	119.8	163.1	-89	156.8	0	0	0	108.4
379	S	23.3	Very low	26.5	Very low	121 Å²	121	142.8 Å²	142.8	85%	0.846	82%	0.818	S	S	*	*	P	Polyproline II helix	trans	-91.9	125	171.2	59.3	0	0	0	0	110.4
380	L	29.5	Very low	26.6	Very low	176 Å²	176	140.8 Å²	140.8	92%	0.921	81%	0.81	S	S	*	*			trans	-120.3	135	167.4	-151.8	79.2	0	0	0	108.5
381	D	24.9	Very low	26.7	Very low	155 Å²	155	138.1 Å²	138.1	83%	0.829	81%	0.809	S	S	*	*			trans	-87.4	142.8	-174.2	-164.7	11.9	0	0	0	113
382	S	27.3	Very low	27.1	Very low	91 Å²	91	140 Å²	140	64%	0.636	81%	0.811	S	S	*	*	S	Bend	trans	49.6	111.9	167.4	-132.1	0	0	0	0	121.9
383	R	27.5	Very low	27.2	Very low	244 Å²	244	135.1 Å²	135.1	92%	0.921	80%	0.797	S	S	*	*	S	Bend	trans	84.7	84.7	159.8	-54.5	-169.3	-166.2	-160	3.9	118.3
384	G	30.3	Very low	27.1	Very low	77 Å²	77	135.4 Å²	135.4	79%	0.794	80%	0.799	S	S	*	*				96.8	106.1	119.1	0	0	0	0	0	118.3
385	A	28.9	Very low	27.3	Very low	92 Å²	92	131 Å²	131	76%	0.76	78%	0.783	S	S	*	*			trans	81.6	124.3	166.3	0	0	0	0	0	118.5	C387	A385-C387 PolarHBondContact O-N 2.77Å
386	P	28.3	Very low	27.4	Very low	132 Å²	132	131.7 Å²	131.7	86%	0.857	78%	0.783	S	S	*	*	P	Polyproline II helix	trans	-79.5	117.2	175.8	30.3	-30.4	0	0	0	111.3
387	C	28	Very low	27.7	Very low	120 Å²	120	128 Å²	128	81%	0.811	76%	0.763	S	S	*	*	P	Polyproline II helix	trans	-83.2	124.5	165.8	-75.5	0	0	0	0	110.3	A385	A385-C387 PolarHBondContact O-N 2.77Å
388	R	26.1	Very low	28	Very low	247 Å²	247	126.2 Å²	126.2	93%	0.932	76%	0.755	S	S	*	*	P	Polyproline II helix	trans	-71.6	128	166.1	-73.4	-177	-177.1	-148.3	0.9	109.2
389	L	26.6	Very low	28.3	Very low	157 Å²	157	128.4 Å²	128.4	82%	0.822	75%	0.752	S	S	*	*	P	Polyproline II helix	trans	-103.6	121.4	167.9	-87.2	147.5	0	0	0	108.5
390	S	24.8	Very low	28.5	Very low	88 Å²	88	128.3 Å²	128.3	62%	0.615	75%	0.746	S	S	*	*	P	Polyproline II helix	trans	-75.2	158.5	177.9	-68.9	0	0	0	0	112.2	S392	S390-S392 PolarHBondContact O-N 3.44Å
391	P	28.2	Very low	28.6	Very low	139 Å²	139	126.1 Å²	126.1	90%	0.903	74%	0.743	S	S	*	*	S	Bend	trans	-77.6	21	-165	-11.3	28.8	0	0	0	116.5
392	S	30.6	Very low	28.8	Very low	112 Å²	112	124 Å²	124	78%	0.783	74%	0.74	S	S	*	*			trans	-128.6	32.3	-166.8	50.8	0	0	0	0	115.8	S390	S390-S392 PolarHBondContact O-N 3.44Å
393	S	28.7	Very low	28.8	Very low	75 Å²	75	124.2 Å²	124.2	52%	0.524	74%	0.741	S	S	.	*			trans	-116.8	114.2	173.1	59.9	0	0	0	0	112.4	V395	S393-V395 PolarHBondContact O-N 2.98Å
394	S	28.7	Very low	29.3	Very low	118 Å²	118	124.4 Å²	124.4	83%	0.825	74%	0.742	S	S	*	*			trans	-69.7	115	165.8	43.8	0	0	0	0	109.6
395	V	33.8	Very low	29.6	Very low	68 Å²	68	128.3 Å²	128.3	41%	0.412	75%	0.745	S	S	.	*			trans	-104.9	118.5	174.9	177.6	0	0	0	0	108.7	S393 V411	S393-V395 PolarHBondContact O-N 2.98Å; V395-V411 HydrophobicContact CG1-CG1 3.83Å
396	A	27.8	Very low	29.7	Very low	77 Å²	77	128.4 Å²	128.4	64%	0.636	74%	0.74	S	S	*	*			trans	-87.8	126.2	171.5	0	0	0	0	0	109.8
397	L	30.8	Very low	30	Very low	105 Å²	105	133 Å²	133	55%	0.55	74%	0.74	S	S	.	*			trans	-102.9	119.3	172.6	-76	160.2	0	0	0	108.8	W409	L397-W409 HydrophobicContact CD2-CE3 4.36Å
398	S	28.9	Very low	30.2	Very low	82 Å²	82	133.2 Å²	133.2	57%	0.573	73%	0.729	S	S	*	*			trans	-113.2	144.8	171	63.1	0	0	0	0	110.5
399	R	30.7	Very low	30.7	Very low	220 Å²	220	128.3 Å²	128.3	83%	0.83	71%	0.711	S	S	*	*			trans	-100	122.3	176.2	-177.6	177.5	173.9	173.1	-2.1	108.3
400	T	27.3	Very low	31	Very low	120 Å²	120	126.3 Å²	126.3	74%	0.736	70%	0.695	S	S	*	*			trans	-84.4	142.6	173.7	50.9	0	0	0	0	110.6
401	P	33.4	Very low	31.4	Very low	130 Å²	130	124.9 Å²	124.9	84%	0.844	68%	0.683	S	S	*	*			trans	-98.4	94.5	179.9	34	-26	0	0	0	110.4
402	S	28.9	Very low	31.6	Very low	110 Å²	110	123 Å²	123	77%	0.769	66%	0.661	S	S	*	*			trans	-167.1	146.7	144.3	103.4	0	0	0	0	113.7
403	S	26.6	Very low	31.6	Very low	96 Å²	96	122.8 Å²	122.8	67%	0.671	66%	0.659	S	S	*	*			trans	75.3	119.3	175.6	82.5	0	0	0	0	117.7	D405	S403-D405 PolarHBondContact O-N 3.06Å
404	R	37	Very low	31.6	Very low	248 Å²	248	125.6 Å²	125.6	94%	0.936	67%	0.673	S	S	*	*	T	Hydrogen-bonded Turn	trans	-60.5	94	170.5	-78.9	169.9	160.9	170.7	-6.5	109.1
405	D	38.6	Very low	31.7	Very low	158 Å²	158	122.8 Å²	122.8	85%	0.845	66%	0.663	S	S	*	*	T	Hydrogen-bonded Turn	trans	160.4	0	140.8	-90.6	-23.4	0	0	0	117	S403	S403-D405 PolarHBondContact O-N 3.06Å
406	S	29.6	Very low	31.6	Very low	95 Å²	95	125.1 Å²	125.1	66%	0.664	68%	0.679	S	S	*	*			trans	-92.6	125.2	-171.7	-62	0	0	0	0	115.5	E408	S406-E408 PolarHBondContact O-N 2.93Å
407	R	35.9	Very low	31.6	Very low	229 Å²	229	129.2 Å²	129.2	86%	0.864	69%	0.688	S	S	*	*			trans	-92.6	67.4	171.2	-62.1	179.9	-156.2	172.8	7.2	111.3
408	E	32	Very low	31.5	Very low	124 Å²	124	127.6 Å²	127.6	58%	0.579	70%	0.697	S	S	*	*			trans	-132.7	136.1	-179.5	-68.7	-171.4	161.6	0	0	112.2	S406 V432	S406-E408 PolarHBondContact O-N 2.93Å; E408-V432 HydrophobicContact CG-CG1 4.41Å
409	W	36	Very low	31.5	Very low	144 Å²	144	127.7 Å²	127.7	55%	0.545	71%	0.711	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-119.6	129.1	174.2	-64.1	85.2	0	0	0	108.3	L397	L397-W409 HydrophobicContact CD2-CE3 4.36Å
410	K	32.3	Very low	31.6	Very low	114 Å²	114	121.5 Å²	121.5	50%	0.496	72%	0.716	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-99.5	134.9	173	-77.5	-177.2	175.8	178.7	0	109.7	F412 A430	K410-F412 HydrophobicContact CB-CE2 4.32Å; K410-A430 HydrophobicContact CB-CB 4.46Å; K410-A430 HydrophobicContact CD-CB 3.8Å; K410-A430 HydrophobicContact CG-CB 4.06Å
411	V	33.8	Very low	31.5	Very low	59 Å²	59	119.7 Å²	119.7	36%	0.358	72%	0.721	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-95.4	128	174.2	175.7	0	0	0	0	108.8	V395	V395-V411 HydrophobicContact CG1-CG1 3.83Å
412	F	32.2	Very low	31.4	Very low	100 Å²	100	123.4 Å²	123.4	44%	0.439	73%	0.727	S	S	.	*			trans	-110.6	127.8	168.2	-72.4	-84.1	0	0	0	109.4	K410	K410-F412 HydrophobicContact CB-CE2 4.32Å
413	S	31.1	Very low	31.4	Very low	106 Å²	106	121.6 Å²	121.6	74%	0.741	73%	0.726	S	S	*	*			trans	-93.6	121.6	167.9	-75.6	0	0	0	0	108.8
414	V	29.6	Very low	31.6	Very low	135 Å²	135	123.4 Å²	123.4	82%	0.818	74%	0.735	S	S	*	*			trans	-87.6	111.2	165.7	178.4	0	0	0	0	106.7
415	G	29	Very low	31.4	Very low	59 Å²	59	116.8 Å²	116.8	61%	0.608	73%	0.733	S	S	*	*			trans	-77.6	152.8	170.1	0	0	0	0	0	110.7
416	P	31.6	Very low	30.8	Very low	116 Å²	116	116.6 Å²	116.6	75%	0.753	73%	0.732	S	S	*	*			trans	-81.9	165.2	177.5	34.5	-31.5	0	0	0	111.4
417	I	28	Very low	30.7	Very low	163 Å²	163	118.3 Å²	118.3	84%	0.836	74%	0.739	S	S	*	*			trans	127.5	127.7	144.8	-62.9	158.3	0	0	0	112.9
418	G	28.5	Very low	30.4	Very low	71 Å²	71	112 Å²	112	73%	0.732	73%	0.73	S	S	*	*			trans	-81.2	166.5	169.1	0	0	0	0	0	113.4
419	G	28.8	Very low	30.3	Very low	84 Å²	84	117.7 Å²	117.7	87%	0.866	75%	0.746	S	S	*	*			trans	101.6	99.4	160.4	0	0	0	0	0	116.5
420	G	32.6	Very low	29.9	Very low	91 Å²	91	112.8 Å²	112.8	94%	0.938	74%	0.736	S	S	*	*			trans	77	117.4	144.2	0	0	0	0	0	119.5
421	G	26.6	Very low	29.8	Very low	82 Å²	82	115.6 Å²	115.6	85%	0.845	75%	0.749	S	S	*	*			trans	139.7	118.2	157.3	0	0	0	0	0	115.2
422	E	31.7	Very low	29.5	Very low	208 Å²	208	116.6 Å²	116.6	97%	0.972	76%	0.755	S	S	*	*			trans	-67.8	148.4	174.7	-68.5	168.8	116.4	0	0	113.4
423	G	27.5	Very low	29.4	Very low	71 Å²	71	115.1 Å²	115.1	73%	0.732	76%	0.761	S	S	*	*			trans	136.4	149.7	159.9	0	0	0	0	0	116.1
424	P	30.3	Very low	29.1	Very low	135 Å²	135	118.5 Å²	118.5	88%	0.877	76%	0.762	S	S	*	*			trans	-87	158.3	-143	34	-35	0	0	0	116.1
425	A	33.3	Very low	29	Very low	108 Å²	108	120 Å²	120	89%	0.893	77%	0.765	S	S	*	*			trans	-55.4	127.5	-169.9	0	0	0	0	0	115.4
426	D	25.7	Very low	28.9	Very low	154 Å²	154	123.4 Å²	123.4	82%	0.824	78%	0.778	S	S	*	*			trans	-123.5	135.4	166.8	-141.3	-14.1	0	0	0	111.8
427	T	29	Very low	28.8	Very low	132 Å²	132	123.5 Å²	123.5	81%	0.81	77%	0.772	S	S	*	*			trans	-53.7	124.1	-164.5	18.1	0	0	0	0	116.6	R429	T427-R429 PolarHBondContact O-N 3.5Å
428	S	29.3	Very low	28.9	Very low	95 Å²	95	125.7 Å²	125.7	66%	0.664	78%	0.775	S	S	*	*			trans	-77.8	118.8	170.7	52.7	0	0	0	0	112.2	A430	S428-A430 PolarHBondContact O-N 3.39Å
429	R	28.9	Very low	29	Very low	245 Å²	245	126.6 Å²	126.6	93%	0.925	77%	0.771	S	S	*	*			trans	-61.9	111.4	176.7	-90.7	178.3	171.1	173.4	-2.6	111.8	T427	T427-R429 PolarHBondContact O-N 3.5Å
430	A	28.2	Very low	29	Very low	41 Å²	41	130.3 Å²	130.3	34%	0.339	77%	0.77	S	S	.	*	P	Polyproline II helix	trans	-79.1	126.9	168.2	0	0	0	0	0	111	K410 S428	K410-A430 HydrophobicContact CB-CB 4.46Å; K410-A430 HydrophobicContact CD-CB 3.8Å; K410-A430 HydrophobicContact CG-CB 4.06Å; S428-A430 PolarHBondContact O-N 3.39Å
431	K	29.5	Very low	28.9	Very low	173 Å²	173	137.1 Å²	137.1	75%	0.752	77%	0.767	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-100	135	168.4	-72.5	-178.6	179.6	178.6	0	109.8
432	V	28.8	Very low	29	Very low	80 Å²	80	144 Å²	144	49%	0.485	77%	0.768	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-100.4	128.7	-176.7	-179.1	0	0	0	0	109.3	E408	E408-V432 HydrophobicContact CG-CG1 4.41Å
433	A	28.7	Very low	29	Very low	68 Å²	68	142 Å²	142	56%	0.562	76%	0.763	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-116.3	135	172.7	0	0	0	0	0	110.3
434	K	26.6	Very low	28.9	Very low	177 Å²	177	144.7 Å²	144.7	77%	0.77	77%	0.769	S	S	*	*			trans	-109.7	114.5	-176.5	-144	173.8	-168	169.2	0	109.7
435	L	27	Very low	28.7	Very low	168 Å²	168	144.4 Å²	144.4	88%	0.88	77%	0.769	S	S	*	*			trans	-94	117.9	178.1	-158.4	83.8	0	0	0	110.2
436	C	27.2	Very low	28.3	Very low	130 Å²	130	144.7 Å²	144.7	88%	0.878	76%	0.764	S	S	*	*			trans	-99.7	109.1	171.1	-85.1	0	0	0	0	110.3
437	N	27.9	Very low	28.3	Very low	118 Å²	118	145.1 Å²	145.1	63%	0.631	76%	0.764	S	S	*	*			trans	-112.4	125.9	166.4	-170.5	-6.8	0	0	0	110.2	S439	N437-S439 PolarHBondContact ND2-OG 3.01Å; N437-S439 PolarHBondContact O-N 3.22Å; N437-S439 PolarHBondContact OD1-N 3.06Å; N437-S439 VanDerWaalsContact OD1-N 3.15Å
438	K	30.1	Very low	28.1	Very low	208 Å²	208	147 Å²	147	90%	0.904	77%	0.769	S	S	*	*	G	3₁₀ helix	trans	-74.7	-2.2	179.5	-91.7	179.7	177.2	175.1	0	114.1	L440	K438-L440 PolarHBondContact O-N 3.1Å
439	S	30.6	Very low	27.9	Very low	91 Å²	91	147.8 Å²	147.8	64%	0.636	77%	0.774	S	S	*	*	G	3₁₀ helix	trans	-90.1	9.4	-174.8	83.8	0	0	0	0	116.4	N437	N437-S439 PolarHBondContact ND2-OG 3.01Å; N437-S439 PolarHBondContact O-N 3.22Å; N437-S439 PolarHBondContact OD1-N 3.06Å; N437-S439 VanDerWaalsContact OD1-N 3.15Å
440	L	29.4	Very low	27.9	Very low	162 Å²	162	141.3 Å²	141.3	85%	0.848	76%	0.764	S	S	*	*	G	3₁₀ helix	trans	-114.4	16.9	176.7	-129	93.7	0	0	0	114.2	K438 R442	K438-L440 PolarHBondContact O-N 3.1Å; L440-R442 PolarHBondContact O-N 3.34Å
441	R	29.9	Very low	27.8	Very low	234 Å²	234	147.7 Å²	147.7	88%	0.883	79%	0.786	S	S	*	*			trans	-93.7	75.9	169.1	-90.6	-167.8	171.9	-155.9	-0.2	110.3
442	R	30.3	Very low	27.6	Very low	227 Å²	227	146.1 Å²	146.1	86%	0.857	79%	0.791	S	S	*	*			trans	171	88.6	150	-99	165.8	-177.5	-172.2	-0.8	108.4	L440	L440-R442 PolarHBondContact O-N 3.34Å
443	N	30.4	Very low	27.7	Very low	164 Å²	164	148.2 Å²	148.2	88%	0.877	81%	0.807	S	S	*	*	S	Bend	trans	-175.5	79.9	145.2	-90.8	-8.2	0	0	0	107.1
444	C	26	Very low	28	Very low	128 Å²	128	150.8 Å²	150.8	87%	0.865	82%	0.818	S	S	*	*			trans	-177.3	78.5	154.6	-102.2	0	0	0	0	107
445	C	25.9	Very low	27.9	Very low	129 Å²	129	151 Å²	151	87%	0.872	82%	0.822	S	S	*	*			trans	-136.8	79	159.3	-92.7	0	0	0	0	106.4
446	C	25.9	Very low	28	Very low	115 Å²	115	152 Å²	152	78%	0.777	82%	0.821	S	S	*	*	S	Bend	trans	-137.8	113.1	149.5	-77.6	0	0	0	0	106.9
447	I	25.2	Very low	28	Very low	163 Å²	163	150.5 Å²	150.5	84%	0.836	82%	0.818	S	S	*	*			trans	70.6	96.9	143.4	-51	170.3	0	0	0	115.6
448	L	23.9	Very low	27.8	Very low	172 Å²	172	149.1 Å²	149.1	90%	0.901	82%	0.824	S	S	*	*			trans	-82.5	125.7	154.7	-136.7	89.8	0	0	0	107.5
449	S	24.8	Very low	27.7	Very low	111 Å²	111	145.7 Å²	145.7	78%	0.776	82%	0.82	S	S	*	*			trans	-148.5	143.9	140	-100	0	0	0	0	108.7
450	P	30.6	Very low	27.6	Very low	109 Å²	109	148 Å²	148	71%	0.708	83%	0.83	S	S	*	*			trans	-100.7	165	-161.6	36.3	-26.8	0	0	0	113.7
451	E	25.9	Very low	27.4	Very low	175 Å²	175	143.4 Å²	143.4	82%	0.818	82%	0.822	S	S	*	*			trans	122.4	114.8	149.1	-63	-164.3	152.3	0	0	117.9
452	T	25.4	Very low	27.4	Very low	140 Å²	140	140.1 Å²	140.1	86%	0.859	82%	0.822	S	S	*	*			trans	126.8	137.4	144.5	55.7	0	0	0	0	117.5
453	P	29.3	Very low	27.2	Very low	124 Å²	124	137 Å²	137	81%	0.805	82%	0.821	S	S	*	*			trans	-107.4	-173	-166.1	49.3	-38.2	0	0	0	111.7
454	P	35	Very low	27	Very low	122 Å²	122	134.8 Å²	134.8	79%	0.792	82%	0.816	S	S	*	*				-108.6	159.8	-124.2	36.6	-19.4	0	0	0	115.6
455	Q	25.7	Very low	26.9	Very low	182 Å²	182	135.2 Å²	135.2	85%	0.85	82%	0.815	S	S	*	*			trans	-139.9	123.7	159	-107.8	176.4	0.4	0	0	112.8
456	E	27.7	Very low	26.9	Very low	187 Å²	187	136.3 Å²	136.3	87%	0.874	81%	0.81	S	S	*	*			trans	52.6	141.8	145.7	-76.5	172.1	154.1	0	0	125.3
457	A	27.2	Very low	26.9	Very low	99 Å²	99	139 Å²	139	82%	0.818	81%	0.809	S	S	*	*			trans	-60.3	153	-175.2	0	0	0	0	0	117
458	A	24.6	Very low	27.1	Very low	90 Å²	90	138.1 Å²	138.1	74%	0.744	80%	0.804	S	S	*	*				-176.3	126.2	128.4	0	0	0	0	0	114
459	V	27.4	Very low	27.2	Very low	135 Å²	135	137.4 Å²	137.4	82%	0.818	80%	0.796	S	S	*	*			trans	62.6	99.2	135.1	-167.4	0	0	0	0	121.4
460	V	29.3	Very low	27.3	Very low	140 Å²	140	139.1 Å²	139.1	85%	0.848	79%	0.791	S	S	*	*			trans	10.2	123.6	132.9	-171.3	0	0	0	0	119.4
461	G	24.9	Very low	27.2	Very low	66 Å²	66	141.8 Å²	141.8	68%	0.68	80%	0.799	S	S	*	*			trans	-156.4	132.3	157	0	0	0	0	0	110.1
462	D	30.5	Very low	27.1	Very low	165 Å²	165	138.5 Å²	138.5	88%	0.882	80%	0.795	S	S	*	*			trans	-51.4	133.8	-161.1	-68.3	-51.4	0	0	0	118
463	L	26.4	Very low	27.2	Very low	161 Å²	161	140.2 Å²	140.2	84%	0.843	80%	0.798	S	S	*	*			trans	-113.4	139.9	167.3	-122	85.2	0	0	0	110.5	T465	L463-T465 PolarHBondContact O-N 3.43Å
464	P	25.1	Very low	27	Very low	117 Å²	117	138.6 Å²	138.6	76%	0.76	79%	0.79	S	S	*	*			trans	-73.4	126.4	-168.8	28.4	-32.2	0	0	0	112.6	I466	P464-I466 PolarHBondContact O-N 3.07Å
465	T	25.2	Very low	26.8	Very low	138 Å²	138	140.6 Å²	140.6	85%	0.847	79%	0.794	S	S	*	*			trans	-67.5	113.5	170.1	10.4	0	0	0	0	111.3	L463	L463-T465 PolarHBondContact O-N 3.43Å
466	I	25.4	Very low	27	Very low	151 Å²	151	141.2 Å²	141.2	77%	0.774	79%	0.794	S	S	*	*			trans	-87.4	106.7	166.7	-61.4	172.3	0	0	0	107.8	P464 I468	P464-I466 PolarHBondContact O-N 3.07Å; I466-I468 HydrophobicContact CG2-CG1 4.34Å
467	K	25.1	Very low	27.5	Very low	172 Å²	172	135.7 Å²	135.7	75%	0.748	79%	0.787	S	S	*	*			trans	-80.6	114	168.3	-83.2	-177.1	175.9	179.1	0	109.2
468	I	28.8	Very low	27.4	Very low	144 Å²	144	140.1 Å²	140.1	74%	0.738	79%	0.791	S	S	*	*			trans	-87.1	108.8	169.5	-58	174.1	0	0	0	107	I466	I466-I468 HydrophobicContact CG2-CG1 4.34Å
469	H	26.3	Very low	27.5	Very low	157 Å²	157	140.4 Å²	140.4	73%	0.727	79%	0.793	S	S	*	*			trans	-95.8	106.1	169.8	-81.5	-87.1	0	0	0	109
470	Q	27.6	Very low	27.6	Very low	147 Å²	147	142.2 Å²	142.2	69%	0.687	80%	0.804	S	S	*	*			trans	71.5	133.1	156.2	-144.5	166.4	-16.2	0	0	119
471	L	27.5	Very low	27.6	Very low	166 Å²	166	142.3 Å²	142.3	87%	0.869	80%	0.802	S	S	*	*			trans	-118.7	113.8	167.1	-105.6	147.5	0	0	0	105.9
472	S	24.8	Very low	27.7	Very low	105 Å²	105	146.3 Å²	146.3	73%	0.734	81%	0.808	S	S	*	*			trans	-103.8	132.8	172.7	57.4	0	0	0	0	110.4
473	L	27	Very low	27.5	Very low	177 Å²	177	145.3 Å²	145.3	93%	0.927	80%	0.804	S	S	*	*			trans	-121.2	108.4	164.1	-98	149.1	0	0	0	105
474	S	26.2	Very low	27.6	Very low	90 Å²	90	144.4 Å²	144.4	63%	0.629	80%	0.802	S	S	*	*			trans	-95.6	124.3	173.6	176.5	0	0	0	0	108.4
475	D	30.6	Very low	27.8	Very low	163 Å²	163	146.1 Å²	146.1	87%	0.872	80%	0.804	S	S	*	*	S	Bend	trans	-127.8	100.7	154.3	-134.6	1.1	0	0	0	106
476	K	30.1	Very low	27.9	Very low	195 Å²	195	146.6 Å²	146.6	85%	0.848	80%	0.802	S	S	*	*	S	Bend	trans	96.3	113.2	-173.1	-57.1	177.3	179.5	-175.8	0	114.1
477	G	37.8	Very low	28.1	Very low	71 Å²	71	146.3 Å²	146.3	73%	0.732	80%	0.804	S	S	*	*			trans	-66.6	128.5	-172.5	0	0	0	0	0	113.2
478	E	25	Very low	28.3	Very low	192 Å²	192	144.3 Å²	144.3	90%	0.897	81%	0.808	S	S	*	*			trans	-161.3	150.3	138.9	-105.4	175.5	-174	0	0	106.7
479	A	26.1	Very low	28.3	Very low	96 Å²	96	144.3 Å²	144.3	79%	0.793	81%	0.814	S	S	*	*			trans	-77.7	127.7	-166.6	0	0	0	0	0	113
480	V	30.9	Very low	28.5	Very low	173 Å²	173	143.2 Å²	143.2	100%	1.048	82%	0.822	S	S	*	*			trans	-144.4	0	149.6	-177.6	0	0	0	0	109.8

Retrieved 480 of 480 residues in 233.1 ms (Link to these results)

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