A0A087YAI6_POEFO Loading...

Equilibrative nucleoside transporter 4

AlphaFold DB , UniProt , Accession A0A087YAI6, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 553 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	32.2	Very low	29	Very low	233 Å²	233	146.9 Å²	146.9	100%	1.148	84%	0.836	S	S	*	*				0	133.7	0	-97.3	165.9	153.1	0	0	108
2	H	29	Very low	28.6	Very low	181 Å²	181	141.3 Å²	141.3	84%	0.838	84%	0.835	S	S	*	*			trans	38.4	122.1	171.2	-60.5	-56.2	0	0	0	119.5
3	S	27.4	Very low	28.7	Very low	100 Å²	100	138.6 Å²	138.6	70%	0.699	84%	0.838	S	S	*	*				86.3	142.2	51.3	-172	0	0	0	0	114.1
4	S	27.7	Very low	28.6	Very low	110 Å²	110	142.6 Å²	142.6	77%	0.769	84%	0.844	S	S	*	*			trans	95.5	104.5	156	-48	0	0	0	0	119.2
5	R	29.8	Very low	28.3	Very low	238 Å²	238	149.5 Å²	149.5	90%	0.898	85%	0.849	S	S	*	*			trans	-63.4	162.5	137.4	-99.5	-177.6	-177.7	-175.9	1.4	109
6	P	40.2	Very low	28.2	Very low	102 Å²	102	155.8 Å²	155.8	66%	0.662	86%	0.855	S	S	*	*				-155.5	177.2	58.5	42.6	-20.9	0	0	0	119.2
7	E	27.7	Very low	27.9	Very low	177 Å²	177	160.8 Å²	160.8	83%	0.827	86%	0.858	S	S	*	*			trans	55.8	167.4	146.5	-73.5	163.9	-158.3	0	0	122
8	L	27.7	Very low	28	Very low	171 Å²	171	158.9 Å²	158.9	90%	0.895	86%	0.856	S	S	*	*			cis	-171.6	141.5	-46.6	-160.1	127.4	0	0	0	107.1
9	G	24.1	Very low	28	Very low	59 Å²	59	157.7 Å²	157.7	61%	0.608	86%	0.855	S	S	*	*			trans	129.3	144	152.2	0	0	0	0	0	121.3
10	S	25.2	Very low	28.1	Very low	135 Å²	135	155.9 Å²	155.9	94%	0.944	85%	0.851	S	S	*	*			trans	80.2	142.2	163.5	79.9	0	0	0	0	119.4
11	A	28.5	Very low	28.3	Very low	110 Å²	110	153.4 Å²	153.4	91%	0.909	85%	0.851	S	S	*	*			trans	-123.5	151.4	-175.6	0	0	0	0	0	110.4
12	G	23.5	Very low	28.1	Very low	80 Å²	80	151.5 Å²	151.5	83%	0.825	84%	0.84	S	S	*	*			trans	-154	128.7	-179.9	0	0	0	0	0	112.1
13	A	30.8	Very low	28.2	Very low	106 Å²	106	149.1 Å²	149.1	88%	0.876	84%	0.838	S	S	*	*			trans	-62.7	160.6	-172.4	0	0	0	0	0	116.3
14	E	26.5	Very low	28.6	Very low	195 Å²	195	149.6 Å²	149.6	91%	0.911	84%	0.839	S	S	*	*			trans	-148.1	133.8	151.3	-140.2	170.6	177.8	0	0	114
15	R	24.8	Very low	28.7	Very low	245 Å²	245	151.9 Å²	151.9	93%	0.925	84%	0.843	S	S	*	*			trans	-88.1	145.2	175.6	-72.8	-177.1	175.3	-157.8	-0.1	110.5
16	R	25.5	Very low	28.9	Very low	250 Å²	250	147 Å²	147	94%	0.943	83%	0.834	S	S	*	*			trans	-112.2	152	168	-72.8	-168.3	174.4	-149.8	-1.3	113.2
17	R	23.6	Very low	28.8	Very low	242 Å²	242	152.2 Å²	152.2	91%	0.913	84%	0.841	S	S	*	*			trans	-89.9	165.1	-177.2	-77.5	-173.4	-173.7	-175	3.7	112.3
18	P	30.7	Very low	29.2	Very low	127 Å²	127	149.9 Å²	149.9	83%	0.825	83%	0.834	S	S	*	*			trans	-87.2	168.4	-168.6	35.6	-37.3	0	0	0	115.2
19	V	27.4	Very low	29.4	Very low	136 Å²	136	143.4 Å²	143.4	82%	0.824	81%	0.808	S	S	*	*			trans	-133.9	147.5	-179.6	176	0	0	0	0	108.1
20	P	30.1	Very low	30	Very low	120 Å²	120	149.9 Å²	149.9	78%	0.779	82%	0.815	S	S	*	*			trans	-91.1	175	-156	35.9	-36.9	0	0	0	116.5
21	A	31.7	Very low	30.5	Very low	104 Å²	104	152 Å²	152	86%	0.86	80%	0.802	S	S	*	*			trans	-71.5	157.8	-170.4	0	0	0	0	0	115.8
22	Q	29.4	Very low	30.9	Very low	194 Å²	194	152.7 Å²	152.7	91%	0.907	79%	0.79	S	S	*	*			trans	-117.9	158.3	176.8	-74.6	-179.9	-27.8	0	0	112.7
23	T	29.1	Very low	31.4	Very low	130 Å²	130	157.8 Å²	157.8	80%	0.798	79%	0.785	S	S	*	*			trans	-92.9	167.8	-171.4	40.1	0	0	0	0	113.9
24	P	37.2	Very low	31.7	Very low	110 Å²	110	154.7 Å²	154.7	71%	0.714	76%	0.763	S	S	*	*	S	Bend	trans	-97.3	97.8	-166.7	35.9	-31.8	0	0	0	114.5
25	D	30.3	Very low	32.3	Very low	159 Å²	159	149.9 Å²	149.9	85%	0.85	74%	0.743	S	S	*	*			trans	-138.2	6.7	169.6	-87.1	-48.9	0	0	0	114.3	W27	D25-W27 PolarHBondContact O-N 2.73Å
26	D	33.3	Very low	32.8	Very low	134 Å²	134	141 Å²	141	72%	0.717	72%	0.722	S	S	*	*			trans	-99.1	23.2	-164.6	-133.8	-6	0	0	0	115.2
27	W	38.5	Very low	33.2	Very low	212 Å²	212	131.5 Å²	131.5	80%	0.803	70%	0.702	S	S	*	*	S	Bend	trans	-87.8	-22.8	-169.5	-91.3	90.8	0	0	0	116.1	D25	D25-W27 PolarHBondContact O-N 2.73Å
28	D	34.8	Very low	33.9	Very low	128 Å²	128	130.3 Å²	130.3	68%	0.684	70%	0.697	S	S	*	*	G	3₁₀ helix	trans	-82.9	-29.5	-177.1	-74.6	-35	0	0	0	113.1	W30 R31	D28-W30 PolarHBondContact O-N 2.92Å; D28-R31 PolarHBondContact O-N 3.24Å; D28-R31 VanDerWaalsContact O-N 3.15Å
29	G	32	Very low	34.1	Very low	35 Å²	35	132.1 Å²	132.1	36%	0.361	69%	0.688	S	S	.	*	G	3₁₀ helix	trans	-67	-6.9	178.6	0	0	0	0	0	115.8	R33	G29-R33 PolarHBondContact O-NE 3.34Å; G29-R33 PolarHBondContact O-NH2 3.05Å
30	W	37.2	Very low	34.5	Very low	195 Å²	195	129.7 Å²	129.7	74%	0.739	67%	0.67	S	S	*	*	G	3₁₀ helix	trans	-96.8	-25.5	175.2	-80.8	88.5	0	0	0	113.4	D28 G34	D28-W30 PolarHBondContact O-N 2.92Å; W30-G34 PolarHBondContact O-N 3.02Å
31	R	36.6	Very low	34.9	Very low	179 Å²	179	127.1 Å²	127.1	68%	0.675	66%	0.659	S	S	*	*	H	α-helix	trans	-72.5	-41.9	-174.3	-167.1	178.3	-72.2	-109.1	3.3	112	D28 I35	D28-R31 PolarHBondContact O-N 3.24Å; D28-R31 VanDerWaalsContact O-N 3.15Å; R31-I35 WeakPolarHBondContact O-CG1 3.29Å
32	D	35.4	Very low	35.1	Very low	125 Å²	125	124.4 Å²	124.4	67%	0.668	64%	0.641	S	S	*	*	H	α-helix	trans	-77.5	-36.5	-176.8	-73.8	-19.1	0	0	0	113.7	G34 I35 A36	D32-G34 VanDerWaalsContact C-N 3.29Å; D32-G34 PolarHBondContact O-N 3.36Å; D32-I35 PolarHBondContact O-N 3.34Å; D32-A36 PolarHBondContact O-N 3.13Å
33	R	33.9	Very low	35.3	Very low	187 Å²	187	122.3 Å²	122.3	71%	0.706	63%	0.625	S	S	*	*	H	α-helix	trans	-65.3	-32.5	176.1	-84.2	-177.3	-76.9	-152.7	-2	112.7	G29 I35	G29-R33 PolarHBondContact O-NE 3.34Å; G29-R33 PolarHBondContact O-NH2 3.05Å; R33-I35 VanDerWaalsContact C-N 3.33Å; R33-I35 PolarHBondContact O-N 3.14Å
34	G	37.3	Very low	35.4	Very low	41 Å²	41	123 Å²	123	42%	0.423	62%	0.619	S	S	.	*	H	α-helix	trans	-68.1	-27.6	174.1	0	0	0	0	0	114.1	W30 D32	W30-G34 PolarHBondContact O-N 3.02Å; D32-G34 VanDerWaalsContact C-N 3.29Å; D32-G34 PolarHBondContact O-N 3.36Å
35	I	40	Very low	35.3	Very low	94 Å²	94	120.6 Å²	120.6	48%	0.482	62%	0.615	S	S	.	*	H	α-helix	trans	-88.3	-28	-175.4	-66.5	169.9	0	0	0	112.1	R31 D32 R33	R31-I35 WeakPolarHBondContact O-CG1 3.29Å; D32-I35 PolarHBondContact O-N 3.34Å; R33-I35 VanDerWaalsContact C-N 3.33Å; R33-I35 PolarHBondContact O-N 3.14Å
36	A	33.9	Very low	35.4	Very low	59 Å²	59	124 Å²	124	49%	0.488	62%	0.616	S	S	.	*	H	α-helix	trans	-69.5	-52.4	176.8	0	0	0	0	0	112.4	D32 W38 R39	D32-A36 PolarHBondContact O-N 3.13Å; A36-W38 VanDerWaalsContact C-N 3.26Å; A36-W38 PolarHBondContact O-N 3.35Å; A36-W38 VanDerWaalsContact O-N 3.15Å; A36-R39 PolarHBondContact O-N 3.13Å
37	G	34.6	Very low	35.3	Very low	51 Å²	51	128.1 Å²	128.1	53%	0.526	62%	0.621	S	S	.	*	H	α-helix	trans	-60.7	-29.1	-172.7	0	0	0	0	0	115.2
38	W	38.5	Very low	35	Very low	216 Å²	216	126.3 Å²	126.3	82%	0.818	62%	0.622	S	S	*	*	H	α-helix	trans	-79.9	-18.6	178.3	-74.4	76.7	0	0	0	113.8	A36 G42	A36-W38 VanDerWaalsContact C-N 3.26Å; A36-W38 PolarHBondContact O-N 3.35Å; A36-W38 VanDerWaalsContact O-N 3.15Å; W38-G42 PolarHBondContact O-N 3.46Å
39	R	35.7	Very low	34.9	Very low	165 Å²	165	124 Å²	124	62%	0.623	63%	0.628	S	S	*	*	H	α-helix	trans	-80.7	-21.5	-177.2	-158.2	179.4	-68.5	-130.6	3.3	112.9	A36 R43	A36-R39 PolarHBondContact O-N 3.13Å; R39-R43 PolarHBondContact O-NH2 3.41Å
40	D	34.3	Very low	34.8	Very low	86 Å²	86	133.3 Å²	133.3	46%	0.46	65%	0.652	S	S	.	*	H	α-helix	trans	-100.9	-37.4	-179.6	-65	-35.2	0	0	0	112.9	G42 R43 E44	D40-G42 PolarHBondContact O-N 3.19Å; D40-R43 WeakPolarHBondContact O-CA 3.49Å; D40-R43 WeakPolarHBondContact O-CB 3.45Å; D40-R43 PolarHBondContact O-N 3.05Å; D40-R43 IonicContact OD1-CZ 3.43Å; D40-R43 IonicContact OD1-NE 2.76Å; D40-R43 PolarHBondContact OD1-NE 3.48Å; D40-R43 IonicContact OD1-NH2 2.72Å; D40-R43 PolarHBondContact OD1-NH2 2.8Å; D40-E44 PolarHBondContact O-N 3.22Å
41	A	38.9	Very low	34.5	Very low	66 Å²	66	132.7 Å²	132.7	55%	0.545	66%	0.657	S	S	.	*	H	α-helix	trans	-57.6	-34.5	168.7	0	0	0	0	0	112.5	R43	A41-R43 PolarHBondContact O-N 3.3Å
42	G	35.2	Very low	34.2	Very low	47 Å²	47	129.9 Å²	129.9	49%	0.485	67%	0.666	S	S	.	*	H	α-helix	trans	-73.3	-4.5	173.6	0	0	0	0	0	115.2	W38 D40 W46	W38-G42 PolarHBondContact O-N 3.46Å; D40-G42 PolarHBondContact O-N 3.19Å; G42-W46 VanDerWaalsContact O-CD1 3.27Å
43	R	33.6	Very low	34.1	Very low	150 Å²	150	127.9 Å²	127.9	57%	0.566	68%	0.675	S	S	*	*	H	α-helix	trans	-105.1	-31.5	-176.8	-127.7	-173.2	-60	-115.4	10.4	113	R39 D40 A41	R39-R43 PolarHBondContact O-NH2 3.41Å; D40-R43 WeakPolarHBondContact O-CA 3.49Å; D40-R43 WeakPolarHBondContact O-CB 3.45Å; D40-R43 PolarHBondContact O-N 3.05Å; D40-R43 IonicContact OD1-CZ 3.43Å; D40-R43 IonicContact OD1-NE 2.76Å; D40-R43 PolarHBondContact OD1-NE 3.48Å; D40-R43 IonicContact OD1-NH2 2.72Å; D40-R43 PolarHBondContact OD1-NH2 2.8Å; A41-R43 PolarHBondContact O-N 3.3Å
44	E	32.4	Very low	33.7	Very low	144 Å²	144	125.2 Å²	125.2	67%	0.673	68%	0.678	S	S	*	*	H	α-helix	trans	-74.2	-45.3	179	-66.5	179	152	0	0	111.4	D40 W46 R47	D40-E44 PolarHBondContact O-N 3.22Å; E44-W46 PolarHBondContact O-N 2.94Å; E44-R47 PolarHBondContact O-N 3.46Å
45	G	34.3	Very low	33.4	Very low	60 Å²	60	129.6 Å²	129.6	62%	0.619	70%	0.697	S	S	*	*	T	Hydrogen-bonded Turn	trans	-63.4	-9	177.7	0	0	0	0	0	115.9
46	W	33.6	Very low	32.7	Very low	231 Å²	231	132.2 Å²	132.2	88%	0.875	71%	0.707	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.1	-3.7	172.6	-81.8	84.3	0	0	0	113.8	G42 E44	G42-W46 VanDerWaalsContact O-CD1 3.27Å; E44-W46 PolarHBondContact O-N 2.94Å
47	R	30.3	Very low	32.2	Very low	220 Å²	220	134.2 Å²	134.2	83%	0.83	72%	0.718	S	S	*	*	T	Hydrogen-bonded Turn	trans	-103.2	-28.2	-176.2	-137.8	177.3	-139.2	-100.6	3.4	114	E44 G49	E44-R47 PolarHBondContact O-N 3.46Å; R47-G49 VanDerWaalsContact C-N 3.35Å
48	E	32.2	Very low	31.7	Very low	174 Å²	174	140.7 Å²	140.7	81%	0.813	73%	0.728	S	S	*	*	S	Bend	trans	-77.1	-17.7	178.8	-69.2	-177.9	132.8	0	0	113.8	R50	E48-R50 PolarHBondContact O-N 3.24Å
49	G	32.8	Very low	30.9	Very low	79 Å²	79	135.1 Å²	135.1	81%	0.814	72%	0.722	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.1	20.9	-177.9	0	0	0	0	0	116.5	R47	R47-G49 VanDerWaalsContact C-N 3.35Å
50	R	30.5	Very low	30.4	Very low	230 Å²	230	137.2 Å²	137.2	87%	0.868	74%	0.735	S	S	*	*	T	Hydrogen-bonded Turn	trans	-126.7	-10.7	-171.7	-137.5	178.6	-169.2	176.1	4	117.8	E48	E48-R50 PolarHBondContact O-N 3.24Å
51	E	31	Very low	30	Very low	182 Å²	182	139.2 Å²	139.2	85%	0.85	75%	0.746	S	S	*	*	S	Bend	trans	-138	88.7	-179.1	-69.7	-172.2	174.3	0	0	113.2
52	S	29.6	Very low	29.4	Very low	121 Å²	121	140.7 Å²	140.7	85%	0.846	75%	0.752	S	S	*	*			trans	174.1	104.7	137.7	37.1	0	0	0	0	109.9
53	G	32.9	Very low	29.1	Very low	83 Å²	83	149.3 Å²	149.3	86%	0.856	77%	0.772	S	S	*	*			trans	-90.9	119.5	170.9	0	0	0	0	0	110.6
54	V	26.9	Very low	28.6	Very low	130 Å²	130	151.7 Å²	151.7	79%	0.788	79%	0.79	S	S	*	*			trans	-132	121.7	159.3	-179.2	0	0	0	0	108.2
55	V	29.5	Very low	28.6	Very low	134 Å²	134	152.5 Å²	152.5	81%	0.812	80%	0.798	S	S	*	*			trans	-80.9	124.2	175.2	175.3	0	0	0	0	108.7
56	Q	25.8	Very low	28.2	Very low	148 Å²	148	158.3 Å²	158.3	69%	0.692	81%	0.809	S	S	*	*			trans	-134.9	109.9	153.7	-77.4	-162.1	-30	0	0	110.5	Y58	Q56-Y58 HydrophobicContact CB-CD2 4.45Å; Q56-Y58 HydrophobicContact CB-CE2 4.05Å
57	S	23.8	Very low	27.9	Very low	102 Å²	102	155.9 Å²	155.9	71%	0.713	81%	0.807	S	S	*	*			trans	-77.4	130.5	166.1	52.1	0	0	0	0	109.8
58	Y	24	Very low	27.8	Very low	187 Å²	187	153.6 Å²	153.6	73%	0.733	81%	0.806	S	S	*	*			trans	-124.3	107.5	159.3	-77.5	-77.7	0	0	0	109.6	Q56	Q56-Y58 HydrophobicContact CB-CD2 4.45Å; Q56-Y58 HydrophobicContact CB-CE2 4.05Å
59	S	22.6	Very low	27.6	Very low	99 Å²	99	154.8 Å²	154.8	69%	0.692	81%	0.812	S	S	*	*			trans	-66.9	148	157.6	-170	0	0	0	0	108.2
60	F	25.3	Very low	27.3	Very low	208 Å²	208	157.6 Å²	157.6	91%	0.912	81%	0.806	S	S	*	*			trans	-126.5	103.7	165.2	-130.6	-88.3	0	0	0	108.1
61	D	25.3	Very low	27.1	Very low	128 Å²	128	152.5 Å²	152.5	68%	0.684	81%	0.806	S	S	*	*			trans	-105.7	157	177.5	-141.7	-36.9	0	0	0	110.3
62	S	25.9	Very low	26.9	Very low	97 Å²	97	152.2 Å²	152.2	68%	0.678	80%	0.802	S	S	*	*			trans	-16.8	140.5	174.6	37.8	0	0	0	0	121.5
63	Y	28.5	Very low	26.7	Very low	228 Å²	228	154.1 Å²	154.1	89%	0.894	80%	0.803	S	S	*	*			trans	-20.2	141.1	158.2	-68.1	-102	0	0	0	118.7
64	Q	24.1	Very low	26.4	Very low	201 Å²	201	154.9 Å²	154.9	94%	0.939	80%	0.801	S	S	*	*			trans	-154.2	160.2	134.4	-120.8	168.1	-21.5	0	0	113.6
65	L	30.7	Very low	26.5	Very low	161 Å²	161	154.5 Å²	154.5	84%	0.843	80%	0.801	S	S	*	*			trans	-96.3	-172.9	-179.6	-80.6	157.6	0	0	0	110.9
66	E	27	Very low	26.6	Very low	181 Å²	181	156 Å²	156	85%	0.846	80%	0.799	S	S	*	*			trans	78.6	147.9	172.8	-60.9	171.2	-173.8	0	0	115.5
67	E	27.1	Very low	26.6	Very low	180 Å²	180	160.5 Å²	160.5	84%	0.841	81%	0.81	S	S	*	*			cis	-155.5	-173.9	-36.3	-142.1	169.8	-158.7	0	0	107.4
68	E	29	Very low	26.8	Very low	172 Å²	172	159 Å²	159	80%	0.804	81%	0.811	S	S	*	*			trans	-65.4	146.5	-174.4	-57.6	179.4	124.5	0	0	114.5
69	E	26.9	Very low	27	Very low	200 Å²	200	156.7 Å²	156.7	94%	0.935	82%	0.816	S	S	*	*			trans	-148.3	145.6	137.2	-129.2	-179.3	-151.8	0	0	112.7
70	I	27.4	Very low	27.3	Very low	138 Å²	138	159.8 Å²	159.8	71%	0.708	82%	0.823	S	S	*	*			trans	-103.3	134.3	-161.5	-68.2	165.1	0	0	0	111.3	K72	I70-K72 HydrophobicContact CG2-CG 4.41Å
71	S	25.6	Very low	27.6	Very low	123 Å²	123	153.8 Å²	153.8	86%	0.86	81%	0.813	S	S	*	*			trans	-127.8	114	164.4	-178.3	0	0	0	0	110.7
72	K	26.8	Very low	28.1	Very low	175 Å²	175	154.8 Å²	154.8	76%	0.761	82%	0.817	S	S	*	*			trans	-91	139.2	171.5	-72.2	176.6	170.9	174.9	0	109.8	I70	I70-K72 HydrophobicContact CG2-CG 4.41Å
73	D	25.1	Very low	28.4	Very low	162 Å²	162	155.3 Å²	155.3	87%	0.866	82%	0.821	S	S	*	*				167.6	103.4	115.4	-87.7	-18.1	0	0	0	112.8
74	A	28	Very low	28.6	Very low	99 Å²	99	151.8 Å²	151.8	82%	0.818	81%	0.813	S	S	*	*			trans	-174.7	132.2	145.8	0	0	0	0	0	110
75	P	28.8	Very low	29	Very low	121 Å²	121	147.2 Å²	147.2	79%	0.786	80%	0.8	S	S	*	*			trans	-97.4	148.6	-172.2	35.7	-34.5	0	0	0	115.8
76	E	30.8	Very low	29	Very low	167 Å²	167	147 Å²	147	78%	0.78	80%	0.8	S	S	*	*			trans	48.2	108.8	149.6	-59.3	-167.6	169.3	0	0	121.1
77	R	26.8	Very low	29.4	Very low	241 Å²	241	147.5 Å²	147.5	91%	0.909	80%	0.8	S	S	*	*				173.4	131.1	96.3	-92	175	-173.3	-175.4	0.8	111.6
78	G	27.1	Very low	30.1	Very low	71 Å²	71	147.4 Å²	147.4	73%	0.732	80%	0.799	S	S	*	*	S	Bend	trans	137.4	94.4	158	0	0	0	0	0	116.2
79	V	28.3	Very low	31	Very low	138 Å²	138	145.8 Å²	145.8	84%	0.836	79%	0.791	S	S	*	*			trans	58.6	101.4	155	-168.2	0	0	0	0	116.7	A81	V79-A81 PolarHBondContact O-N 3.36Å
80	L	29.7	Very low	32.4	Very low	164 Å²	164	141.6 Å²	141.6	86%	0.859	78%	0.782	S	S	*	*			trans	-65.7	85.4	156.9	-79.7	166.3	0	0	0	109.9	L82	L80-L82 VanDerWaalsContact C-N 3.26Å; L80-L82 PolarHBondContact O-N 3.43Å; L80-L82 VanDerWaalsContact O-N 3.09Å
81	A	31.6	Very low	34.2	Very low	83 Å²	83	140.7 Å²	140.7	69%	0.686	78%	0.777	S	S	*	*			trans	-72	90.7	154.4	0	0	0	0	0	107.2	V79 S83	V79-A81 PolarHBondContact O-N 3.36Å; A81-S83 PolarHBondContact O-N 2.95Å
82	L	35.3	Very low	36.3	Very low	149 Å²	149	136.2 Å²	136.2	78%	0.78	75%	0.745	S	S	*	*			trans	-62.6	94.9	158.8	-73.3	173.4	0	0	0	106.6	L80 E84	L80-L82 VanDerWaalsContact C-N 3.26Å; L80-L82 PolarHBondContact O-N 3.43Å; L80-L82 VanDerWaalsContact O-N 3.09Å; L82-E84 VanDerWaalsContact C-N 3.29Å; L82-E84 PolarHBondContact O-N 2.87Å
83	S	31.6	Very low	38.5	Very low	108 Å²	108	134 Å²	134	76%	0.755	74%	0.741	S	S	*	*			trans	-62.1	98.2	160.5	51.9	0	0	0	0	106.6	A81	A81-S83 PolarHBondContact O-N 2.95Å
84	E	32.5	Very low	41	Very low	154 Å²	154	126.5 Å²	126.5	72%	0.72	70%	0.701	S	S	*	*	P	Polyproline II helix	trans	-51.7	131.2	161.5	-67	-178.3	157.2	0	0	106.6	L82 D86	L82-E84 VanDerWaalsContact C-N 3.29Å; L82-E84 PolarHBondContact O-N 2.87Å; E84-D86 PolarHBondContact O-N 3.33Å; E84-D86 VanDerWaalsContact O-N 3.12Å
85	P	33.1	Very low	43.1	Very low	104 Å²	104	131.2 Å²	131.2	68%	0.675	70%	0.698	S	S	*	*	P	Polyproline II helix	trans	-60.2	123.7	174.7	25.6	-32.2	0	0	0	107.2	F87	P85-F87 PolarHBondContact O-N 3.49Å
86	D	30.8	Very low	45.3	Very low	157 Å²	157	135.2 Å²	135.2	84%	0.84	70%	0.699	S	S	*	*	P	Polyproline II helix	trans	-49.2	116	167.8	-92.3	-45.6	0	0	0	107	E84 E88	E84-D86 PolarHBondContact O-N 3.33Å; E84-D86 VanDerWaalsContact O-N 3.12Å; D86-E88 PolarHBondContact O-N 3.36Å
87	F	35.2	Very low	47.9	Very low	192 Å²	192	132.6 Å²	132.6	84%	0.842	69%	0.687	S	S	*	*			trans	-71.2	75.8	174.7	-98.2	-92.6	0	0	0	108	P85 Q89	P85-F87 PolarHBondContact O-N 3.49Å; F87-Q89 PolarHBondContact O-N 2.94Å
88	E	42.3	Very low	50.7	Low	178 Å²	178	123 Å²	123	83%	0.832	66%	0.663	S	S	*	*			trans	-49	113.9	157.4	-73.3	-162.2	149.7	0	0	106.4	D86 P90	D86-E88 PolarHBondContact O-N 3.36Å; E88-P90 WeakPolarHBondContact O-CD 3.48Å
89	Q	48	Very low	53.6	Low	137 Å²	137	120.5 Å²	120.5	64%	0.64	63%	0.632	S	S	*	*			trans	-58.2	119.4	177.5	-72.8	-176	6.7	0	0	106.8	F87 I91 Y289	F87-Q89 PolarHBondContact O-N 2.94Å; Q89-I91 PolarHBondContact O-N 2.92Å; Q89-I91 VanDerWaalsContact O-N 3.1Å; Q89-Y289 HydrophobicContact CB-CE2 4.24Å
90	P	55.1	Low	56.5	Low	112 Å²	112	116.4 Å²	116.4	73%	0.727	60%	0.602	S	S	*	*			trans	-57.2	126.2	-172.8	21.4	-32.8	0	0	0	108	E88 P92	E88-P90 WeakPolarHBondContact O-CD 3.48Å; P90-P92 WeakPolarHBondContact O-CD 3.43Å
91	I	66.1	Low	59.4	Low	119 Å²	119	114.8 Å²	114.8	61%	0.61	59%	0.588	S	S	*	*			trans	-47.6	114.7	-176.2	-61.6	173.1	0	0	0	106.9	Q89 D93 Y290	Q89-I91 PolarHBondContact O-N 2.92Å; Q89-I91 VanDerWaalsContact O-N 3.1Å; I91-D93 PolarHBondContact O-N 3.31Å; I91-D93 VanDerWaalsContact O-N 3.14Å; I91-Y290 VanDerWaalsContact CG2-OH 3.28Å; I91-Y290 WeakPolarHBondContact CG2-OH 3.35Å
92	P	70.1	Confident	62.3	Low	30 Å²	30	111.2 Å²	111.2	20%	0.195	56%	0.559	C	S	.	*			trans	-62.9	125.4	-169.1	22	-32.1	0	0	0	108.5	P90 F286 Y289	P90-P92 WeakPolarHBondContact O-CD 3.43Å; P92-F286 HydrophobicContact CB-CB 4.47Å; P92-F286 HydrophobicContact CB-CD2 4.26Å; P92-F286 HydrophobicContact CG-CD2 4.25Å; P92-F286 WeakPolarHBondContact O-CD2 3.38Å; P92-F286 WeakPolarHBondContact O-CE2 3.35Å; P92-Y289 HydrophobicContact CG-CD1 3.85Å; P92-Y289 HydrophobicContact CG-CD2 4.32Å; P92-Y289 HydrophobicContact CG-CG 3.73Å
93	D	72.1	Confident	65	Low	127 Å²	127	104.1 Å²	104.1	68%	0.679	52%	0.522	S	S	*	.			trans	-84.6	150.1	-179.8	-172	32.2	0	0	0	112	I91 R95	I91-D93 PolarHBondContact O-N 3.31Å; I91-D93 VanDerWaalsContact O-N 3.14Å; D93-R95 VanDerWaalsContact C-N 3.3Å; D93-R95 PolarHBondContact O-N 3.39Å
94	D	78.6	Confident	67.9	Low	5 Å²	5	100.4 Å²	100.4	3%	0.027	49%	0.493	C	S	.	.			trans	-84.7	73.8	178.6	-172.7	2.9	0	0	0	109.6	Y96 H97 G98 I99 Y100 Y227 F286	D94-Y96 PolarHBondContact O-N 3.07Å; D94-Y96 VanDerWaalsContact O-N 3.15Å; D94-H97 WeakPolarHBondContact O-CA 3.5Å; D94-H97 PolarHBondContact O-N 2.94Å; D94-G98 PolarHBondContact OD1-N 3.39Å; D94-G98 VanDerWaalsContact OD1-N 3.17Å; D94-I99 WeakPolarHBondContact OD1-CB 3.48Å; D94-I99 WeakPolarHBondContact OD1-CG1 3.3Å; D94-I99 PolarHBondContact OD1-N 3.01Å; D94-I99 WeakPolarHBondContact OD2-CB 3.34Å; D94-Y100 PolarHBondContact OD2-N 3.42Å; D94-Y100 VanDerWaalsContact OD2-N 3.1Å; D94-Y227 VanDerWaalsContact CB-OH 3.25Å; D94-Y227 WeakPolarHBondContact CB-OH 3.24Å; D94-Y227 VanDerWaalsContact CG-OH 3.31Å; D94-Y227 WeakPolarHBondContact OD2-CE1 3.17Å; D94-Y227 PolarHBondContact OD2-OH 2.97Å; D94-F286 HydrophobicContact CB-CE2 4.29Å
95	R	71	Confident	70.8	Confident	199 Å²	199	94.6 Å²	94.6	75%	0.751	47%	0.467	S	S	*	.	G	3₁₀ helix	trans	-52.8	121.4	-177.1	-174.9	179.6	-89.1	-167.9	-7.7	110.6	D93 H97	D93-R95 VanDerWaalsContact C-N 3.3Å; D93-R95 PolarHBondContact O-N 3.39Å; R95-H97 VanDerWaalsContact C-N 3.31Å; R95-H97 PolarHBondContact O-N 2.81Å
96	Y	74.9	Confident	73.6	Confident	204 Å²	204	89.8 Å²	89.8	80%	0.8	44%	0.436	S	S	*	.	G	3₁₀ helix	trans	65.4	16.6	-173.7	-51.8	-67.4	0	0	0	116.4	D94 G98	D94-Y96 PolarHBondContact O-N 3.07Å; D94-Y96 VanDerWaalsContact O-N 3.15Å; Y96-G98 PolarHBondContact O-N 3.35Å; Y96-G98 VanDerWaalsContact O-N 3.1Å
97	H	84.8	Confident	76.5	Confident	113 Å²	113	82.3 Å²	82.3	52%	0.523	40%	0.396	S	S	.	.	G	3₁₀ helix	trans	56.2	21.7	-175.9	-56	96.3	0	0	0	113.8	D94 R95 I99 Y100 F101	D94-H97 WeakPolarHBondContact O-CA 3.5Å; D94-H97 PolarHBondContact O-N 2.94Å; R95-H97 VanDerWaalsContact C-N 3.31Å; R95-H97 PolarHBondContact O-N 2.81Å; H97-I99 VanDerWaalsContact C-N 3.27Å; H97-I99 PolarHBondContact O-N 2.92Å; H97-Y100 WeakPolarHBondContact O-CB 3.44Å; H97-Y100 PolarHBondContact O-N 2.71Å; H97-Y100 VanDerWaalsContact O-N 3.09Å; H97-F101 HydrophobicContact CB-CD2 4.29Å; H97-F101 HydrophobicContact CB-CE2 4.3Å; H97-F101 WeakPolarHBondContact O-CD2 3.3Å; H97-F101 PolarHBondContact O-N 2.9Å
98	G	85.8	Confident	79.2	Confident	40 Å²	40	73.2 Å²	73.2	41%	0.412	36%	0.356	S	S	.	.	H	α-helix	trans	-64.2	-31.5	-172.7	0	0	0	0	0	113.1	D94 Y96 A102	D94-G98 PolarHBondContact OD1-N 3.39Å; D94-G98 VanDerWaalsContact OD1-N 3.17Å; Y96-G98 PolarHBondContact O-N 3.35Å; Y96-G98 VanDerWaalsContact O-N 3.1Å; G98-A102 WeakPolarHBondContact O-CB 3.34Å; G98-A102 PolarHBondContact O-N 3.45Å; G98-A102 VanDerWaalsContact O-N 3.09Å
99	I	87.9	Confident	81.5	Confident	18 Å²	18	64.8 Å²	64.8	9%	0.092	32%	0.317	C	S	.	.	H	α-helix	trans	-72.2	-41.2	174.9	-56.5	174	0	0	0	109.5	D94 H97 F101 A102 M103 Y227 V281 F286	D94-I99 WeakPolarHBondContact OD1-CB 3.48Å; D94-I99 WeakPolarHBondContact OD1-CG1 3.3Å; D94-I99 PolarHBondContact OD1-N 3.01Å; D94-I99 WeakPolarHBondContact OD2-CB 3.34Å; H97-I99 VanDerWaalsContact C-N 3.27Å; H97-I99 PolarHBondContact O-N 2.92Å; I99-F101 PolarHBondContact O-N 3.29Å; I99-A102 PolarHBondContact O-N 2.9Å; I99-M103 HydrophobicContact CG2-CE 3.63Å; I99-M103 HydrophobicContact CG2-CG 4.47Å; I99-M103 WeakPolarHBondContact O-CG 3.5Å; I99-M103 PolarHBondContact O-N 2.89Å; I99-Y227 HydrophobicContact CB-CE1 4.06Å; I99-Y227 HydrophobicContact CG2-CD1 4.24Å; I99-Y227 HydrophobicContact CG2-CE1 3.76Å; I99-V281 HydrophobicContact CG2-CG1 4.29Å; I99-F286 HydrophobicContact CD1-CB 3.4Å; I99-F286 VanDerWaalsContact CD1-CB 3.4Å; I99-F286 HydrophobicContact CD1-CD1 3.61Å; I99-F286 HydrophobicContact CD1-CD2 4.15Å; I99-F286 HydrophobicContact CD1-CE1 4.47Å; I99-F286 HydrophobicContact CD1-CG 3.45Å; I99-F286 VanDerWaalsContact CD1-CG 3.45Å
100	Y	90	Very high	83.4	Confident	52 Å²	52	58.3 Å²	58.3	20%	0.204	29%	0.287	C	S	.	.	H	α-helix	trans	-59.4	-47.5	175.8	177.2	-92	0	0	0	111.8	D94 H97 A102 M103 L104 R226 Q229	D94-Y100 PolarHBondContact OD2-N 3.42Å; D94-Y100 VanDerWaalsContact OD2-N 3.1Å; H97-Y100 WeakPolarHBondContact O-CB 3.44Å; H97-Y100 PolarHBondContact O-N 2.71Å; H97-Y100 VanDerWaalsContact O-N 3.09Å; Y100-A102 VanDerWaalsContact C-N 3.32Å; Y100-A102 PolarHBondContact O-N 2.89Å; Y100-M103 PolarHBondContact O-N 3.43Å; Y100-L104 HydrophobicContact CE1-CD1 4.3Å; Y100-L104 PolarHBondContact O-N 2.8Å; Y100-R226 WeakPolarHBondContact CE2-O 3.42Å; Y100-Q229 PolarHBondContact OH-OE1 3.22Å; Y100-Q229 VanDerWaalsContact OH-OE1 3.07Å
101	F	91.1	Very high	84.8	Confident	129 Å²	129	54.9 Å²	54.9	57%	0.566	26%	0.262	S	S	*	.	H	α-helix	trans	-60.3	-39.4	174.9	-81.2	-69.8	0	0	0	112.8	H97 I99 L104 L105	H97-F101 HydrophobicContact CB-CD2 4.29Å; H97-F101 HydrophobicContact CB-CE2 4.3Å; H97-F101 WeakPolarHBondContact O-CD2 3.3Å; H97-F101 PolarHBondContact O-N 2.9Å; I99-F101 PolarHBondContact O-N 3.29Å; F101-L104 PolarHBondContact O-N 3.4Å; F101-L105 PolarHBondContact O-N 3.4Å
102	A	91.6	Very high	85.7	Confident	8 Å²	8	49.4 Å²	49.4	7%	0.066	23%	0.234	C	C	.	.	H	α-helix	trans	-68.8	-31.7	176.3	0	0	0	0	0	113.3	G98 I99 Y100 A106 L277 V281	G98-A102 WeakPolarHBondContact O-CB 3.34Å; G98-A102 PolarHBondContact O-N 3.45Å; G98-A102 VanDerWaalsContact O-N 3.09Å; I99-A102 PolarHBondContact O-N 2.9Å; Y100-A102 VanDerWaalsContact C-N 3.32Å; Y100-A102 PolarHBondContact O-N 2.89Å; A102-A106 WeakPolarHBondContact O-CB 3.43Å; A102-A106 PolarHBondContact O-N 3.25Å; A102-L277 HydrophobicContact CB-CB 4.2Å; A102-L277 HydrophobicContact CB-CD1 4.41Å; A102-V281 HydrophobicContact CB-CG2 3.45Å; A102-V281 VanDerWaalsContact CB-CG2 3.45Å
103	M	91.5	Very high	86.6	Confident	1 Å²	1	48 Å²	48	1%	0.005	23%	0.225	C	C	.	.	H	α-helix	trans	-70.4	-40.7	171.7	-63.6	-43.7	176.3	0	0	111.8	I99 Y100 L105 A106 G107 F216 Y219 M220 L223 Y227 V231 V281	I99-M103 HydrophobicContact CG2-CE 3.63Å; I99-M103 HydrophobicContact CG2-CG 4.47Å; I99-M103 WeakPolarHBondContact O-CG 3.5Å; I99-M103 PolarHBondContact O-N 2.89Å; Y100-M103 PolarHBondContact O-N 3.43Å; M103-L105 VanDerWaalsContact C-N 3.35Å; M103-A106 PolarHBondContact O-N 2.96Å; M103-G107 PolarHBondContact O-N 3.27Å; M103-G107 VanDerWaalsContact O-N 3.1Å; M103-F216 HydrophobicContact SD-CE1 3.67Å; M103-F216 HydrophobicContact SD-CZ 3.59Å; M103-F216 VanDerWaalsContact SD-CZ 3.59Å; M103-Y219 HydrophobicContact CE-CE1 3.91Å; M103-Y219 HydrophobicContact SD-CE1 4.39Å; M103-M220 HydrophobicContact CB-SD 4.49Å; M103-M220 HydrophobicContact CE-CE 3.74Å; M103-M220 HydrophobicContact CE-SD 4.4Å; M103-M220 HydrophobicContact CG-CE 4.41Å; M103-M220 HydrophobicContact CG-SD 3.99Å; M103-M220 HydrophobicContact SD-CE 3.58Å; M103-M220 VanDerWaalsContact SD-CE 3.58Å; M103-M220 HydrophobicContact SD-SD 3.91Å; M103-L223 HydrophobicContact CE-CD1 3.64Å; M103-Y227 HydrophobicContact CB-CD1 4.46Å; M103-Y227 HydrophobicContact CG-CD1 3.74Å; M103-Y227 HydrophobicContact CG-CG 4.44Å; M103-V231 HydrophobicContact CB-CG2 3.87Å; M103-V231 WeakPolarHBondContact O-CG2 3.15Å; M103-V281 HydrophobicContact CE-CG1 3.63Å
104	L	93.3	Very high	87.4	Confident	30 Å²	30	43.3 Å²	43.3	16%	0.157	20%	0.198	C	C	.	.	H	α-helix	trans	-59.6	-46.4	172.8	-171.9	157.7	0	0	0	110.7	Y100 F101 A106 G107 V108 G230 T233 G234	Y100-L104 HydrophobicContact CE1-CD1 4.3Å; Y100-L104 PolarHBondContact O-N 2.8Å; F101-L104 PolarHBondContact O-N 3.4Å; L104-A106 PolarHBondContact O-N 2.87Å; L104-G107 PolarHBondContact O-N 3.39Å; L104-V108 HydrophobicContact CD2-CG2 4.36Å; L104-V108 PolarHBondContact O-N 3.28Å; L104-G230 WeakPolarHBondContact CA-O 3.12Å; L104-T233 HydrophobicContact CD1-CG2 4.26Å; L104-G234 WeakPolarHBondContact O-CA 3.07Å
105	L	92.9	Very high	87.7	Confident	32 Å²	32	44.3 Å²	44.3	17%	0.168	20%	0.203	C	C	.	.	H	α-helix	trans	-62.9	-40.7	177	-137.1	81.2	0	0	0	112.3	F101 M103 G107 V108 G109 M270 L273 C274 L277	F101-L105 PolarHBondContact O-N 3.4Å; M103-L105 VanDerWaalsContact C-N 3.35Å; L105-G107 VanDerWaalsContact C-N 3.26Å; L105-G107 PolarHBondContact O-N 3.34Å; L105-V108 WeakPolarHBondContact O-CA 3.32Å; L105-V108 VanDerWaalsContact O-CB 3.32Å; L105-V108 WeakPolarHBondContact O-CB 3.27Å; L105-V108 PolarHBondContact O-N 3.43Å; L105-G109 PolarHBondContact O-N 3.41Å; L105-M270 HydrophobicContact CD1-CE 3.45Å; L105-M270 VanDerWaalsContact CD1-CE 3.45Å; L105-M270 HydrophobicContact CD1-SD 4.2Å; L105-M270 HydrophobicContact CD2-CE 4.36Å; L105-M270 HydrophobicContact CD2-SD 4.12Å; L105-M270 HydrophobicContact CG-CE 3.81Å; L105-M270 HydrophobicContact CG-SD 4.2Å; L105-L273 HydrophobicContact CD2-CB 4.3Å; L105-L273 HydrophobicContact CD2-CD2 3.66Å; L105-L273 HydrophobicContact CD2-CG 3.61Å; L105-C274 PolarHBondContact O-SG 3.47Å; L105-L277 HydrophobicContact CB-CD1 4.29Å; L105-L277 HydrophobicContact CD2-CD1 3.53Å
106	A	92.1	Very high	88.3	Confident	3 Å²	3	34.9 Å²	34.9	3%	0.025	17%	0.167	C	C	.	.	H	α-helix	trans	-57.3	-40.4	175.2	0	0	0	0	0	112	A102 M103 L104 V108 G109 F110 F216	A102-A106 WeakPolarHBondContact O-CB 3.43Å; A102-A106 PolarHBondContact O-N 3.25Å; M103-A106 PolarHBondContact O-N 2.96Å; L104-A106 PolarHBondContact O-N 2.87Å; A106-V108 VanDerWaalsContact C-N 3.33Å; A106-V108 PolarHBondContact O-N 3.36Å; A106-G109 PolarHBondContact O-N 2.82Å; A106-G109 VanDerWaalsContact O-N 3.16Å; A106-F110 HydrophobicContact CB-CE1 4.31Å; A106-F110 HydrophobicContact CB-CZ 4.1Å; A106-F110 WeakPolarHBondContact O-CD1 3.24Å; A106-F110 WeakPolarHBondContact O-CE1 3.49Å; A106-F110 WeakPolarHBondContact O-CG 3.48Å; A106-F110 WeakPolarHBondContact O-CZ 3.28Å; A106-F110 PolarHBondContact O-N 3.47Å; A106-F216 HydrophobicContact CB-CE1 3.93Å; A106-F216 HydrophobicContact CB-CE2 3.76Å; A106-F216 HydrophobicContact CB-CZ 3.36Å
107	G	92.3	Very high	88.7	Confident	0 Å²	0	25.3 Å²	25.3	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-60.8	-37.4	172.8	0	0	0	0	0	113.8	M103 L104 L105 F110 V231 E235	M103-G107 PolarHBondContact O-N 3.27Å; M103-G107 VanDerWaalsContact O-N 3.1Å; L104-G107 PolarHBondContact O-N 3.39Å; L105-G107 VanDerWaalsContact C-N 3.26Å; L105-G107 PolarHBondContact O-N 3.34Å; G107-F110 PolarHBondContact O-N 3.28Å; G107-V231 WeakPolarHBondContact CA-O 3.35Å; G107-E235 WeakPolarHBondContact O-CA 3.39Å
108	V	92.1	Very high	88.5	Confident	1 Å²	1	21.6 Å²	21.6	1%	0.006	11%	0.114	C	C	.	.	H	α-helix	trans	-62.6	-44.6	172.7	178.1	0	0	0	0	110.6	L104 L105 A106 F110 L111 L112 G234 T237 A238 I241 M270	L104-V108 HydrophobicContact CD2-CG2 4.36Å; L104-V108 PolarHBondContact O-N 3.28Å; L105-V108 WeakPolarHBondContact O-CA 3.32Å; L105-V108 VanDerWaalsContact O-CB 3.32Å; L105-V108 WeakPolarHBondContact O-CB 3.27Å; L105-V108 PolarHBondContact O-N 3.43Å; A106-V108 VanDerWaalsContact C-N 3.33Å; A106-V108 PolarHBondContact O-N 3.36Å; V108-F110 VanDerWaalsContact C-N 3.28Å; V108-F110 PolarHBondContact O-N 2.95Å; V108-L111 PolarHBondContact O-N 3.33Å; V108-L112 HydrophobicContact CG1-CD1 3.51Å; V108-L112 HydrophobicContact CG1-CG 3.77Å; V108-L112 PolarHBondContact O-N 3.01Å; V108-L112 VanDerWaalsContact O-N 3.15Å; V108-G234 WeakPolarHBondContact CA-O 3.33Å; V108-G234 WeakPolarHBondContact CG2-O 3.33Å; V108-T237 HydrophobicContact CG2-CG2 4.13Å; V108-A238 HydrophobicContact CG1-CB 4.06Å; V108-I241 HydrophobicContact CG1-CD1 4.33Å; V108-M270 HydrophobicContact CB-CE 4.2Å; V108-M270 HydrophobicContact CG1-CE 3.68Å; V108-M270 HydrophobicContact CG1-CG 4.32Å; V108-M270 HydrophobicContact CG2-CE 4.42Å
109	G	89.7	Confident	87.8	Confident	0 Å²	0	20.5 Å²	20.5	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-62.8	-25	-179.5	0	0	0	0	0	115.2	L105 A106 L111 P113 E271	L105-G109 PolarHBondContact O-N 3.41Å; A106-G109 PolarHBondContact O-N 2.82Å; A106-G109 VanDerWaalsContact O-N 3.16Å; G109-L111 VanDerWaalsContact C-N 3.27Å; G109-L111 PolarHBondContact O-N 3.4Å; G109-P113 WeakPolarHBondContact O-CD 3.5Å; G109-P113 WeakPolarHBondContact O-CG 3.24Å; G109-E271 WeakPolarHBondContact CA-OE2 3.45Å; G109-E271 VanDerWaalsContact O-OE2 3.1Å
110	F	87.8	Confident	87	Confident	1 Å²	1	19.9 Å²	19.9	0%	0.004	10%	0.096	C	C	.	.	H	α-helix	trans	-68.8	-26.5	177.8	-55.1	-21.4	0	0	0	113.4	A106 G107 V108 Q212 Q213 F216 V231	A106-F110 HydrophobicContact CB-CE1 4.31Å; A106-F110 HydrophobicContact CB-CZ 4.1Å; A106-F110 WeakPolarHBondContact O-CD1 3.24Å; A106-F110 WeakPolarHBondContact O-CE1 3.49Å; A106-F110 WeakPolarHBondContact O-CG 3.48Å; A106-F110 WeakPolarHBondContact O-CZ 3.28Å; A106-F110 PolarHBondContact O-N 3.47Å; G107-F110 PolarHBondContact O-N 3.28Å; V108-F110 VanDerWaalsContact C-N 3.28Å; V108-F110 PolarHBondContact O-N 2.95Å; F110-Q212 HydrophobicContact CD1-CG 3.94Å; F110-Q212 HydrophobicContact CE1-CG 3.79Å; F110-Q213 HydrophobicContact CB-CB 4.43Å; F110-Q213 HydrophobicContact CB-CG 4.47Å; F110-Q213 HydrophobicContact CD2-CB 4.06Å; F110-Q213 HydrophobicContact CD2-CG 3.77Å; F110-Q213 HydrophobicContact CE2-CG 4.35Å; F110-Q213 HydrophobicContact CG-CB 4.15Å; F110-Q213 HydrophobicContact CG-CG 4.26Å; F110-F216 HydrophobicContact CE1-CB 4.36Å; F110-F216 HydrophobicContact CE1-CD2 4.17Å; F110-F216 HydrophobicContact CE1-CG 4.26Å; F110-F216 HydrophobicContact CE2-CB 4.08Å; F110-F216 HydrophobicContact CE2-CD1 4.23Å; F110-F216 HydrophobicContact CE2-CG 4.19Å; F110-F216 HydrophobicContact CZ-CB 3.56Å; F110-F216 AromaticContact CZ-CD1 3.72Å; F110-F216 HydrophobicContact CZ-CD1 3.72Å; F110-F216 AromaticContact CZ-CD2 3.72Å; F110-F216 HydrophobicContact CZ-CD2 3.72Å; F110-F216 HydrophobicContact CZ-CE1 4.28Å; F110-F216 HydrophobicContact CZ-CE2 4.27Å; F110-F216 AromaticContact CZ-CG 3.41Å; F110-F216 HydrophobicContact CZ-CG 3.41Å; F110-F216 VanDerWaalsContact CZ-CG 3.41Å; F110-V231 HydrophobicContact CD2-CG1 4.33Å; F110-V231 HydrophobicContact CE2-CG1 3.59Å; F110-V231 HydrophobicContact CZ-CG1 4.44Å
111	L	85.2	Confident	86	Confident	40 Å²	40	18.5 Å²	18.5	21%	0.209	9%	0.093	C	C	.	.	H	α-helix	trans	-108.6	-31.4	-173.3	-80.8	164	0	0	0	113.5	V108 G109 P113 N115 E235 A238	V108-L111 PolarHBondContact O-N 3.33Å; G109-L111 VanDerWaalsContact C-N 3.27Å; G109-L111 PolarHBondContact O-N 3.4Å; L111-P113 VanDerWaalsContact C-CD 3.48Å; L111-N115 WeakPolarHBondContact O-CB 3.49Å; L111-N115 PolarHBondContact O-N 3.46Å; L111-N115 PolarHBondContact O-ND2 3.29Å; L111-E235 HydrophobicContact CD1-CB 3.54Å; L111-E235 HydrophobicContact CD1-CG 3.94Å; L111-E235 WeakPolarHBondContact CD1-O 3.45Å; L111-A238 HydrophobicContact CB-CB 3.94Å
112	L	85.2	Confident	85.1	Confident	4 Å²	4	16.2 Å²	16.2	2%	0.021	9%	0.087	C	C	.	.	H	α-helix	trans	-55.9	-40.1	179.7	-75.6	-176	0	0	0	114.6	V108 Y114 N115 S116 A238 I242 M270	V108-L112 HydrophobicContact CG1-CD1 3.51Å; V108-L112 HydrophobicContact CG1-CG 3.77Å; V108-L112 PolarHBondContact O-N 3.01Å; V108-L112 VanDerWaalsContact O-N 3.15Å; L112-Y114 PolarHBondContact O-N 2.96Å; L112-N115 PolarHBondContact O-N 3.27Å; L112-S116 PolarHBondContact O-N 3.01Å; L112-S116 PolarHBondContact O-OG 2.84Å; L112-A238 HydrophobicContact CD2-CB 4.26Å; L112-A238 HydrophobicContact CG-CB 4.34Å; L112-I242 HydrophobicContact CD2-CD1 4.35Å; L112-I242 HydrophobicContact CD2-CG1 4.17Å; L112-M270 HydrophobicContact CD1-CB 3.8Å; L112-M270 HydrophobicContact CD1-CG 3.48Å; L112-M270 VanDerWaalsContact CD1-CG 3.48Å
113	P	89.1	Confident	84.5	Confident	0 Å²	0	16.7 Å²	16.7	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-57.8	-52.5	-179.3	-29	37	0	0	0	113.3	G109 L111 S116 F117 A172 L176 V205 E271	G109-P113 WeakPolarHBondContact O-CD 3.5Å; G109-P113 WeakPolarHBondContact O-CG 3.24Å; L111-P113 VanDerWaalsContact C-CD 3.48Å; P113-S116 WeakPolarHBondContact O-CB 3.15Å; P113-S116 PolarHBondContact O-N 3.16Å; P113-F117 WeakPolarHBondContact O-CD2 3.18Å; P113-A172 HydrophobicContact CB-CB 4.2Å; P113-A172 HydrophobicContact CG-CB 3.97Å; P113-L176 HydrophobicContact CB-CD1 3.91Å; P113-L176 HydrophobicContact CB-CG 4.44Å; P113-L176 HydrophobicContact CG-CD1 4.18Å; P113-V205 HydrophobicContact CB-CG1 3.64Å; P113-E271 HydrophobicContact CG-CG 4.32Å
114	Y	88.3	Confident	83.9	Confident	29 Å²	29	17 Å²	17	11%	0.114	9%	0.088	C	C	.	.	H	α-helix	trans	-61.7	-46.3	176.7	170.7	-112.6	0	0	0	112	L112 S116 F117 I118 S138 Y141 V202	L112-Y114 PolarHBondContact O-N 2.96Å; Y114-S116 PolarHBondContact O-N 2.79Å; Y114-F117 PolarHBondContact O-N 2.95Å; Y114-I118 HydrophobicContact CD1-CD1 4.26Å; Y114-I118 HydrophobicContact CD1-CG1 4.47Å; Y114-I118 HydrophobicContact CE1-CD1 3.53Å; Y114-I118 HydrophobicContact CE1-CG1 4.08Å; Y114-I118 HydrophobicContact CE2-CG2 3.88Å; Y114-I118 PolarHBondContact O-N 2.91Å; Y114-S138 WeakPolarHBondContact OH-CA 3.32Å; Y114-S138 PolarHBondContact OH-OG 3.41Å; Y114-Y141 HydrophobicContact CD2-CD1 4.23Å; Y114-Y141 AromaticContact CD2-CD2 3.2Å; Y114-Y141 HydrophobicContact CD2-CD2 3.2Å; Y114-Y141 AromaticContact CD2-CE2 3.73Å; Y114-Y141 HydrophobicContact CD2-CE2 3.73Å; Y114-Y141 AromaticContact CD2-CG 3.5Å; Y114-Y141 HydrophobicContact CD2-CG 3.5Å; Y114-Y141 HydrophobicContact CE2-CD1 4.18Å; Y114-Y141 AromaticContact CE2-CD2 3.78Å; Y114-Y141 HydrophobicContact CE2-CD2 3.78Å; Y114-Y141 AromaticContact CE2-CG 3.55Å; Y114-Y141 HydrophobicContact CE2-CG 3.55Å; Y114-Y141 HydrophobicContact CG-CD1 4.47Å; Y114-Y141 AromaticContact CG-CD2 3.69Å; Y114-Y141 HydrophobicContact CG-CD2 3.69Å; Y114-Y141 HydrophobicContact CG-CE1 4.48Å; Y114-Y141 AromaticContact CG-CE2 3.69Å; Y114-Y141 HydrophobicContact CG-CE2 3.69Å; Y114-Y141 HydrophobicContact CG-CG 4.1Å; Y114-V202 HydrophobicContact CD2-CG1 4.47Å
115	N	85.1	Confident	83.2	Confident	27 Å²	27	20.1 Å²	20.1	14%	0.144	10%	0.102	C	C	.	.	H	α-helix	trans	-65.4	-23.9	-178.1	-72.3	-68.7	0	0	0	113	L111 L112 F117 I118 T119 I242	L111-N115 WeakPolarHBondContact O-CB 3.49Å; L111-N115 PolarHBondContact O-N 3.46Å; L111-N115 PolarHBondContact O-ND2 3.29Å; L112-N115 PolarHBondContact O-N 3.27Å; N115-F117 VanDerWaalsContact C-N 3.3Å; N115-F117 PolarHBondContact O-N 3.15Å; N115-I118 PolarHBondContact O-N 3.47Å; N115-T119 VanDerWaalsContact O-CB 3.3Å; N115-T119 WeakPolarHBondContact O-CB 3.26Å; N115-T119 PolarHBondContact O-N 3.24Å; N115-T119 PolarHBondContact O-OG1 3.13Å; N115-I242 HydrophobicContact CB-CD1 3.27Å; N115-I242 HydrophobicContact CB-CG1 3.88Å; N115-I242 WeakPolarHBondContact ND2-CD1 3.42Å
116	S	83.9	Confident	82.6	Confident	0 Å²	0	24.4 Å²	24.4	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-62.3	-34.7	171.2	-55.1	0	0	0	0	112.9	L112 P113 Y114 F264 S267	L112-S116 PolarHBondContact O-N 3.01Å; L112-S116 PolarHBondContact O-OG 2.84Å; P113-S116 WeakPolarHBondContact O-CB 3.15Å; P113-S116 PolarHBondContact O-N 3.16Å; Y114-S116 PolarHBondContact O-N 2.79Å; S116-F264 WeakPolarHBondContact O-CZ 3.21Å; S116-S267 WeakPolarHBondContact OG-CB 3.32Å; S116-S267 PolarHBondContact OG-OG 3.17Å
117	F	84	Confident	82.1	Confident	4 Å²	4	26.4 Å²	26.4	2%	0.018	13%	0.129	C	C	.	.	H	α-helix	trans	-76.9	-32	176.8	-69.5	-84.1	0	0	0	112.9	P113 Y114 N115 L124 M137 L176 V179 V202 V205 F264	P113-F117 WeakPolarHBondContact O-CD2 3.18Å; Y114-F117 PolarHBondContact O-N 2.95Å; N115-F117 VanDerWaalsContact C-N 3.3Å; N115-F117 PolarHBondContact O-N 3.15Å; F117-L124 VanDerWaalsContact O-CD1 3.3Å; F117-L124 WeakPolarHBondContact O-CD1 3.28Å; F117-M137 HydrophobicContact CB-SD 4.07Å; F117-L176 HydrophobicContact CD2-CD2 4.29Å; F117-L176 HydrophobicContact CE2-CD2 3.57Å; F117-L176 HydrophobicContact CE2-CG 4.24Å; F117-L176 HydrophobicContact CZ-CD2 4.07Å; F117-V179 HydrophobicContact CE1-CB 4.01Å; F117-V179 HydrophobicContact CE1-CG1 3.98Å; F117-V179 HydrophobicContact CE1-CG2 3.95Å; F117-V179 HydrophobicContact CZ-CG2 4.49Å; F117-V202 HydrophobicContact CB-CG2 3.76Å; F117-V202 HydrophobicContact CD1-CG2 3.77Å; F117-V202 HydrophobicContact CD2-CG2 4.04Å; F117-V202 HydrophobicContact CE1-CG2 4.4Å; F117-V202 HydrophobicContact CG-CG2 3.57Å; F117-V205 HydrophobicContact CE2-CG2 3.92Å; F117-V205 HydrophobicContact CZ-CG2 4.43Å; F117-F264 HydrophobicContact CD1-CE1 4.5Å; F117-F264 HydrophobicContact CD1-CZ 4.27Å; F117-F264 HydrophobicContact CE1-CE1 4.29Å; F117-F264 HydrophobicContact CE1-CZ 4.41Å; F117-F264 HydrophobicContact CZ-CE1 4.4Å
118	I	78.9	Confident	81.6	Confident	35 Å²	35	26.7 Å²	26.7	18%	0.179	13%	0.13	C	C	.	.	H	α-helix	trans	-101.1	-10.7	-173.5	63.3	152.2	0	0	0	115.3	Y114 N115 V121 V134	Y114-I118 HydrophobicContact CD1-CD1 4.26Å; Y114-I118 HydrophobicContact CD1-CG1 4.47Å; Y114-I118 HydrophobicContact CE1-CD1 3.53Å; Y114-I118 HydrophobicContact CE1-CG1 4.08Å; Y114-I118 HydrophobicContact CE2-CG2 3.88Å; Y114-I118 PolarHBondContact O-N 2.91Å; N115-I118 PolarHBondContact O-N 3.47Å; I118-V121 WeakPolarHBondContact O-CG2 3.29Å; I118-V134 HydrophobicContact CB-CG1 4.49Å; I118-V134 HydrophobicContact CG2-CG1 4.49Å
119	T	72.6	Confident	80.8	Confident	16 Å²	16	33.8 Å²	33.8	10%	0.098	16%	0.163	C	C	.	.	H	α-helix	trans	-75.7	-32.4	179.6	-58.3	0	0	0	0	111.7	N115 V121 I242 F263	N115-T119 VanDerWaalsContact O-CB 3.3Å; N115-T119 WeakPolarHBondContact O-CB 3.26Å; N115-T119 PolarHBondContact O-N 3.24Å; N115-T119 PolarHBondContact O-OG1 3.13Å; T119-V121 PolarHBondContact O-N 3.16Å; T119-I242 HydrophobicContact CG2-CG2 4.37Å; T119-I242 WeakPolarHBondContact OG1-CG2 3.47Å; T119-F263 HydrophobicContact CG2-CD1 4.29Å; T119-F263 HydrophobicContact CG2-CE1 3.78Å; T119-F263 HydrophobicContact CG2-CZ 3.95Å; T119-F263 WeakPolarHBondContact OG1-CE1 3.43Å
120	D	69.8	Low	79.9	Confident	6 Å²	6	38 Å²	38	3%	0.032	21%	0.207	C	C	.	.			trans	-80.1	44.4	179.1	-70.2	-66.2	0	0	0	113.2	D122 Y123 L124 T260	D120-D122 PolarHBondContact O-N 3.35Å; D120-Y123 PolarHBondContact O-N 3.45Å; D120-L124 WeakPolarHBondContact O-CB 3.44Å; D120-L124 WeakPolarHBondContact O-CG 3.38Å; D120-L124 PolarHBondContact O-N 3.46Å; D120-T260 HydrophobicContact CB-CG2 3.92Å; D120-T260 WeakPolarHBondContact CB-OG1 3.36Å; D120-T260 WeakPolarHBondContact OD1-CA 3.41Å; D120-T260 VanDerWaalsContact OD1-CB 3.3Å; D120-T260 WeakPolarHBondContact OD1-CB 3.37Å; D120-T260 PolarHBondContact OD1-OG1 3Å
121	V	69.9	Low	79.3	Confident	23 Å²	23	40.9 Å²	40.9	14%	0.139	23%	0.225	C	C	.	.	H	α-helix	trans	-52.2	-40.4	179.1	178.1	0	0	0	0	111.8	I118 T119 L124 H125 V134	I118-V121 WeakPolarHBondContact O-CG2 3.29Å; T119-V121 PolarHBondContact O-N 3.16Å; V121-L124 PolarHBondContact O-N 3.24Å; V121-H125 VanDerWaalsContact CG1-CD2 3.41Å; V121-H125 WeakPolarHBondContact CG1-CD2 3.35Å; V121-H125 WeakPolarHBondContact O-CB 3.3Å; V121-H125 PolarHBondContact O-CD2 3.32Å; V121-H125 PolarHBondContact O-N 3.26Å; V121-V134 HydrophobicContact CG1-CG2 4.36Å; V121-V134 HydrophobicContact CG2-CG2 4.4Å
122	D	71.9	Confident	78.9	Confident	81 Å²	81	42.1 Å²	42.1	43%	0.433	24%	0.237	S	C	.	.	H	α-helix	trans	-68.1	-51.8	-175.3	-52.3	-49.4	0	0	0	110.8	D120 L124 H125 H126 E256	D120-D122 PolarHBondContact O-N 3.35Å; D122-L124 VanDerWaalsContact C-N 3.3Å; D122-L124 PolarHBondContact O-N 3.47Å; D122-H125 PolarHBondContact O-N 3.01Å; D122-H126 PolarHBondContact O-N 3.45Å; D122-E256 HydrophobicContact CB-CG 4.49Å
123	Y	78.9	Confident	78.8	Confident	17 Å²	17	42 Å²	42	7%	0.067	24%	0.236	C	C	.	.	H	α-helix	trans	-57	-42.2	172.9	173.9	-99.9	0	0	0	112	D120 H126 K127 V184 K257 T260	D120-Y123 PolarHBondContact O-N 3.45Å; Y123-H126 PolarHBondContact O-N 2.98Å; Y123-K127 HydrophobicContact CE1-CD 3.71Å; Y123-K127 WeakPolarHBondContact O-CB 3.49Å; Y123-K127 PolarHBondContact O-N 2.69Å; Y123-K127 WeakPolarHBondContact OH-CD 3.38Å; Y123-K127 PolarHBondContact OH-NZ 2.98Å; Y123-V184 HydrophobicContact CE1-CG2 4.17Å; Y123-K257 HydrophobicContact CE2-CB 4.47Å; Y123-K257 HydrophobicContact CE2-CG 4.44Å; Y123-T260 WeakPolarHBondContact CB-OG1 3.3Å; Y123-T260 HydrophobicContact CD1-CG2 4.15Å; Y123-T260 HydrophobicContact CG-CG2 4.36Å
124	L	80	Confident	78.3	Confident	8 Å²	8	43.4 Å²	43.4	4%	0.042	25%	0.245	C	C	.	.	H	α-helix	trans	-65.9	-42	178.4	-72.5	-179.9	0	0	0	112.4	F117 D120 V121 D122 K127 F128 I133 V134 M137	F117-L124 VanDerWaalsContact O-CD1 3.3Å; F117-L124 WeakPolarHBondContact O-CD1 3.28Å; D120-L124 WeakPolarHBondContact O-CB 3.44Å; D120-L124 WeakPolarHBondContact O-CG 3.38Å; D120-L124 PolarHBondContact O-N 3.46Å; V121-L124 PolarHBondContact O-N 3.24Å; D122-L124 VanDerWaalsContact C-N 3.3Å; D122-L124 PolarHBondContact O-N 3.47Å; L124-K127 PolarHBondContact O-N 2.86Å; L124-F128 HydrophobicContact CD2-CD2 4Å; L124-F128 HydrophobicContact CD2-CE2 3.74Å; L124-F128 WeakPolarHBondContact O-CB 3.49Å; L124-F128 VanDerWaalsContact O-CD2 3.31Å; L124-F128 WeakPolarHBondContact O-CD2 3.26Å; L124-F128 PolarHBondContact O-N 3.49Å; L124-I133 HydrophobicContact CB-CG2 3.88Å; L124-I133 HydrophobicContact CD1-CG2 4.37Å; L124-I133 HydrophobicContact CD2-CD1 4.45Å; L124-I133 HydrophobicContact CG-CG2 4.5Å; L124-V134 HydrophobicContact CB-CG2 4.5Å; L124-V134 HydrophobicContact CD1-CG2 4.06Å; L124-M137 HydrophobicContact CD1-CE 3.86Å; L124-M137 HydrophobicContact CD1-SD 4.19Å; L124-M137 HydrophobicContact CD2-CE 3.98Å
125	H	77.9	Confident	77.9	Confident	95 Å²	95	46.5 Å²	46.5	44%	0.44	26%	0.259	S	S	.	.	H	α-helix	trans	-68.2	-37.3	175.5	-78.6	-44.6	0	0	0	112.6	V121 D122 Q129	V121-H125 VanDerWaalsContact CG1-CD2 3.41Å; V121-H125 WeakPolarHBondContact CG1-CD2 3.35Å; V121-H125 WeakPolarHBondContact O-CB 3.3Å; V121-H125 PolarHBondContact O-CD2 3.32Å; V121-H125 PolarHBondContact O-N 3.26Å; D122-H125 PolarHBondContact O-N 3.01Å; H125-Q129 PolarHBondContact O-N 3.02Å
126	H	80.2	Confident	77.9	Confident	123 Å²	123	47.4 Å²	47.4	57%	0.569	26%	0.264	S	S	*	.	H	α-helix	trans	-66	-41.5	174.8	-174.5	-103.2	0	0	0	112	D122 Y123 Q129 E256	D122-H126 PolarHBondContact O-N 3.45Å; Y123-H126 PolarHBondContact O-N 2.98Å; H126-Q129 WeakPolarHBondContact O-CG 3.41Å; H126-E256 WeakPolarHBondContact CB-OE2 3.16Å; H126-E256 IonicContact CG-OE2 3.6Å
127	K	81.5	Confident	78	Confident	44 Å²	44	47.5 Å²	47.5	19%	0.191	26%	0.264	C	S	.	.	H	α-helix	trans	-74.3	-31.9	179.4	-172.4	170.5	-173.9	175	0	113.9	Y123 L124 D183 T191	Y123-K127 HydrophobicContact CE1-CD 3.71Å; Y123-K127 WeakPolarHBondContact O-CB 3.49Å; Y123-K127 PolarHBondContact O-N 2.69Å; Y123-K127 WeakPolarHBondContact OH-CD 3.38Å; Y123-K127 PolarHBondContact OH-NZ 2.98Å; L124-K127 PolarHBondContact O-N 2.86Å; K127-D183 PolarHBondContact NZ-O 3.03Å; K127-D183 IonicContact NZ-OD1 3.81Å; K127-D183 PolarHBondContact NZ-OD1 3.5Å; K127-D183 IonicContact NZ-OD2 3.43Å; K127-D183 PolarHBondContact NZ-OD2 3.42Å; K127-T191 WeakPolarHBondContact O-CG2 3.47Å
128	F	81.9	Confident	78.1	Confident	7 Å²	7	48.7 Å²	48.7	3%	0.031	27%	0.273	C	S	.	.	T	Hydrogen-bonded Turn	trans	-122.8	46.8	-172.3	-57.9	-75.4	0	0	0	113.1	L124 G130 T131 I133 T191 A194 Y195	L124-F128 HydrophobicContact CD2-CD2 4Å; L124-F128 HydrophobicContact CD2-CE2 3.74Å; L124-F128 WeakPolarHBondContact O-CB 3.49Å; L124-F128 VanDerWaalsContact O-CD2 3.31Å; L124-F128 WeakPolarHBondContact O-CD2 3.26Å; L124-F128 PolarHBondContact O-N 3.49Å; F128-G130 PolarHBondContact O-N 2.97Å; F128-T131 WeakPolarHBondContact CB-OG1 3.49Å; F128-T131 PolarHBondContact O-N 3.08Å; F128-T131 VanDerWaalsContact O-N 3.07Å; F128-T131 PolarHBondContact O-OG1 3.17Å; F128-I133 HydrophobicContact CB-CG2 4.25Å; F128-I133 HydrophobicContact CD1-CD1 4.23Å; F128-I133 HydrophobicContact CD2-CD1 3.43Å; F128-I133 VanDerWaalsContact CD2-CD1 3.43Å; F128-I133 HydrophobicContact CD2-CG2 4.03Å; F128-I133 HydrophobicContact CE1-CD1 4.2Å; F128-I133 HydrophobicContact CE2-CD1 3.4Å; F128-I133 VanDerWaalsContact CE2-CD1 3.4Å; F128-I133 HydrophobicContact CG-CD1 3.86Å; F128-I133 HydrophobicContact CG-CG2 4.43Å; F128-I133 HydrophobicContact CZ-CD1 3.81Å; F128-T191 HydrophobicContact CD1-CG2 3.61Å; F128-T191 HydrophobicContact CE1-CG2 3.83Å; F128-T191 WeakPolarHBondContact CE1-O 3.3Å; F128-A194 HydrophobicContact CE1-CB 4.15Å; F128-A194 HydrophobicContact CZ-CB 3.94Å; F128-Y195 AromaticContact CD1-CD2 3.82Å; F128-Y195 HydrophobicContact CD1-CD2 3.82Å; F128-Y195 HydrophobicContact CE1-CD2 4.06Å; F128-Y195 HydrophobicContact CG-CD2 4.37Å
129	Q	75.8	Confident	78.3	Confident	150 Å²	150	51.2 Å²	51.2	70%	0.701	29%	0.287	S	S	*	.	T	Hydrogen-bonded Turn	trans	-46.7	130.2	-178.3	-61.9	-175.7	-1	0	0	112.5	H125 H126 T131	H125-Q129 PolarHBondContact O-N 3.02Å; H126-Q129 WeakPolarHBondContact O-CG 3.41Å; Q129-T131 VanDerWaalsContact C-N 3.34Å; Q129-T131 PolarHBondContact O-N 2.93Å
130	G	69.8	Low	79.1	Confident	89 Å²	89	52 Å²	52	92%	0.918	29%	0.291	S	S	*	.	T	Hydrogen-bonded Turn	trans	79	5.1	179.2	0	0	0	0	0	115.9	F128	F128-G130 PolarHBondContact O-N 2.97Å
131	T	75.3	Confident	80.1	Confident	61 Å²	61	53 Å²	53	37%	0.374	30%	0.295	S	S	.	.	S	Bend	trans	-120.9	148.7	174.2	70	0	0	0	0	112.3	F128 Q129 I133	F128-T131 WeakPolarHBondContact CB-OG1 3.49Å; F128-T131 PolarHBondContact O-N 3.08Å; F128-T131 VanDerWaalsContact O-N 3.07Å; F128-T131 PolarHBondContact O-OG1 3.17Å; Q129-T131 VanDerWaalsContact C-N 3.34Å; Q129-T131 PolarHBondContact O-N 2.93Å; T131-I133 VanDerWaalsContact C-N 3.27Å; T131-I133 PolarHBondContact O-N 3.4Å
132	S	77.6	Confident	80.9	Confident	66 Å²	66	54.5 Å²	54.5	46%	0.462	30%	0.302	S	S	.	.			trans	-88.8	48.3	-178.5	54.3	0	0	0	0	112.3	V134 F135 D136	S132-V134 VanDerWaalsContact C-N 3.26Å; S132-V134 PolarHBondContact O-N 2.72Å; S132-V134 VanDerWaalsContact O-N 3.13Å; S132-F135 WeakPolarHBondContact O-CA 3.34Å; S132-F135 VanDerWaalsContact O-CB 3.31Å; S132-F135 WeakPolarHBondContact O-CB 3.4Å; S132-F135 PolarHBondContact O-N 2.62Å; S132-D136 PolarHBondContact O-N 3.13Å; S132-D136 VanDerWaalsContact O-N 3.13Å
133	I	82	Confident	81.6	Confident	2 Å²	2	54.1 Å²	54.1	1%	0.01	30%	0.302	C	S	.	.	H	α-helix	trans	-56	-37.2	-169.6	-166.3	174.1	0	0	0	113.8	L124 F128 T131 F135 D136 M137 Y195	L124-I133 HydrophobicContact CB-CG2 3.88Å; L124-I133 HydrophobicContact CD1-CG2 4.37Å; L124-I133 HydrophobicContact CD2-CD1 4.45Å; L124-I133 HydrophobicContact CG-CG2 4.5Å; F128-I133 HydrophobicContact CB-CG2 4.25Å; F128-I133 HydrophobicContact CD1-CD1 4.23Å; F128-I133 HydrophobicContact CD2-CD1 3.43Å; F128-I133 VanDerWaalsContact CD2-CD1 3.43Å; F128-I133 HydrophobicContact CD2-CG2 4.03Å; F128-I133 HydrophobicContact CE1-CD1 4.2Å; F128-I133 HydrophobicContact CE2-CD1 3.4Å; F128-I133 VanDerWaalsContact CE2-CD1 3.4Å; F128-I133 HydrophobicContact CG-CD1 3.86Å; F128-I133 HydrophobicContact CG-CG2 4.43Å; F128-I133 HydrophobicContact CZ-CD1 3.81Å; T131-I133 VanDerWaalsContact C-N 3.27Å; T131-I133 PolarHBondContact O-N 3.4Å; I133-F135 VanDerWaalsContact C-N 3.28Å; I133-F135 PolarHBondContact O-N 2.85Å; I133-D136 PolarHBondContact O-N 2.75Å; I133-M137 HydrophobicContact CD1-CE 3.6Å; I133-M137 HydrophobicContact CG1-CE 3.72Å; I133-M137 HydrophobicContact CG1-CG 4.35Å; I133-M137 WeakPolarHBondContact O-CB 3.5Å; I133-M137 WeakPolarHBondContact O-CG 3.33Å; I133-M137 PolarHBondContact O-N 3.21Å; I133-Y195 HydrophobicContact CB-CD2 4.37Å; I133-Y195 HydrophobicContact CB-CE2 3.7Å; I133-Y195 HydrophobicContact CD1-CD2 3.63Å; I133-Y195 HydrophobicContact CD1-CE2 3.8Å; I133-Y195 HydrophobicContact CD1-CG 4.31Å; I133-Y195 HydrophobicContact CG1-CD2 3.97Å; I133-Y195 HydrophobicContact CG1-CE2 3.58Å
134	V	79.6	Confident	82.2	Confident	29 Å²	29	55 Å²	55	18%	0.176	31%	0.309	C	S	.	.	H	α-helix	trans	-62.7	-35.7	177.5	-176.9	0	0	0	0	111.6	I118 V121 L124 S132 S138	I118-V134 HydrophobicContact CB-CG1 4.49Å; I118-V134 HydrophobicContact CG2-CG1 4.49Å; V121-V134 HydrophobicContact CG1-CG2 4.36Å; V121-V134 HydrophobicContact CG2-CG2 4.4Å; L124-V134 HydrophobicContact CB-CG2 4.5Å; L124-V134 HydrophobicContact CD1-CG2 4.06Å; S132-V134 VanDerWaalsContact C-N 3.26Å; S132-V134 PolarHBondContact O-N 2.72Å; S132-V134 VanDerWaalsContact O-N 3.13Å; V134-S138 WeakPolarHBondContact O-CB 3.44Å; V134-S138 PolarHBondContact O-N 2.76Å; V134-S138 VanDerWaalsContact O-N 3.07Å; V134-S138 PolarHBondContact O-OG 2.85Å
135	F	79.6	Confident	82.7	Confident	94 Å²	94	54.9 Å²	54.9	41%	0.412	31%	0.309	S	S	.	.	H	α-helix	trans	-69	-46.9	174.3	175.1	-93.2	0	0	0	111	S132 I133 M137 S138 L139 Y528	S132-F135 WeakPolarHBondContact O-CA 3.34Å; S132-F135 VanDerWaalsContact O-CB 3.31Å; S132-F135 WeakPolarHBondContact O-CB 3.4Å; S132-F135 PolarHBondContact O-N 2.62Å; I133-F135 VanDerWaalsContact C-N 3.28Å; I133-F135 PolarHBondContact O-N 2.85Å; F135-M137 VanDerWaalsContact C-N 3.34Å; F135-M137 PolarHBondContact O-N 2.89Å; F135-S138 PolarHBondContact O-N 3.29Å; F135-S138 VanDerWaalsContact O-N 3.16Å; F135-L139 HydrophobicContact CE1-CD2 4.18Å; F135-L139 WeakPolarHBondContact O-CB 3.37Å; F135-L139 PolarHBondContact O-N 3.39Å; F135-Y528 AromaticContact CE2-CD2 3.92Å; F135-Y528 HydrophobicContact CE2-CD2 3.92Å; F135-Y528 AromaticContact CE2-CE2 3.96Å; F135-Y528 HydrophobicContact CE2-CE2 3.96Å; F135-Y528 AromaticContact CZ-CD2 3.85Å; F135-Y528 HydrophobicContact CZ-CD2 3.85Å; F135-Y528 AromaticContact CZ-CE2 3.49Å; F135-Y528 HydrophobicContact CZ-CE2 3.49Å; F135-Y528 VanDerWaalsContact CZ-CE2 3.49Å
136	D	83.9	Confident	82.9	Confident	46 Å²	46	52 Å²	52	25%	0.246	30%	0.297	C	S	.	.	H	α-helix	trans	-62.1	-39.9	178.8	-75.3	30.9	0	0	0	112.1	S132 I133 T140 Y195 L199	S132-D136 PolarHBondContact O-N 3.13Å; S132-D136 VanDerWaalsContact O-N 3.13Å; I133-D136 PolarHBondContact O-N 2.75Å; D136-T140 VanDerWaalsContact O-CB 3.28Å; D136-T140 WeakPolarHBondContact O-CB 3.42Å; D136-T140 PolarHBondContact O-N 3.37Å; D136-T140 PolarHBondContact O-OG1 3.12Å; D136-Y195 PolarHBondContact OD2-OH 3.48Å; D136-L199 HydrophobicContact CB-CD1 4.04Å; D136-L199 WeakPolarHBondContact O-CD1 3.46Å
137	M	87.3	Confident	83.2	Confident	1 Å²	1	51.4 Å²	51.4	1%	0.005	30%	0.297	C	S	.	.	H	α-helix	trans	-61.8	-47	172.1	-72.1	-170.4	-167.2	0	0	111.6	F117 L124 I133 F135 T140 Y141 N198 L199 V202	F117-M137 HydrophobicContact CB-SD 4.07Å; L124-M137 HydrophobicContact CD1-CE 3.86Å; L124-M137 HydrophobicContact CD1-SD 4.19Å; L124-M137 HydrophobicContact CD2-CE 3.98Å; I133-M137 HydrophobicContact CD1-CE 3.6Å; I133-M137 HydrophobicContact CG1-CE 3.72Å; I133-M137 HydrophobicContact CG1-CG 4.35Å; I133-M137 WeakPolarHBondContact O-CB 3.5Å; I133-M137 WeakPolarHBondContact O-CG 3.33Å; I133-M137 PolarHBondContact O-N 3.21Å; F135-M137 VanDerWaalsContact C-N 3.34Å; F135-M137 PolarHBondContact O-N 2.89Å; M137-T140 PolarHBondContact O-N 3.42Å; M137-Y141 WeakPolarHBondContact O-CB 3.45Å; M137-Y141 PolarHBondContact O-N 3.04Å; M137-N198 HydrophobicContact CE-CB 3.77Å; M137-L199 HydrophobicContact CG-CD1 4.47Å; M137-V202 HydrophobicContact CB-CG1 4.34Å; M137-V202 HydrophobicContact CB-CG2 4.32Å; M137-V202 HydrophobicContact CG-CG2 4.05Å; M137-V202 WeakPolarHBondContact O-CG1 3.26Å; M137-V202 HydrophobicContact SD-CG2 3.94Å
138	S	85	Confident	83.5	Confident	30 Å²	30	49.3 Å²	49.3	21%	0.21	29%	0.288	C	S	.	.	H	α-helix	trans	-62.1	-45	179.2	-57.9	0	0	0	0	111.7	Y114 V134 F135 Y141 I142	Y114-S138 WeakPolarHBondContact OH-CA 3.32Å; Y114-S138 PolarHBondContact OH-OG 3.41Å; V134-S138 WeakPolarHBondContact O-CB 3.44Å; V134-S138 PolarHBondContact O-N 2.76Å; V134-S138 VanDerWaalsContact O-N 3.07Å; V134-S138 PolarHBondContact O-OG 2.85Å; F135-S138 PolarHBondContact O-N 3.29Å; F135-S138 VanDerWaalsContact O-N 3.16Å; S138-Y141 PolarHBondContact O-N 3.33Å; S138-I142 WeakPolarHBondContact O-CG1 3.42Å; S138-I142 PolarHBondContact O-N 3.07Å
139	L	83.8	Confident	83.4	Confident	88 Å²	88	49.4 Å²	49.4	46%	0.461	29%	0.289	S	S	.	.	H	α-helix	trans	-62	-45.1	176.1	-179.4	63.6	0	0	0	111.4	F135 Y141 I142 V143	F135-L139 HydrophobicContact CE1-CD2 4.18Å; F135-L139 WeakPolarHBondContact O-CB 3.37Å; F135-L139 PolarHBondContact O-N 3.39Å; L139-Y141 PolarHBondContact O-N 3.03Å; L139-I142 PolarHBondContact O-N 3.25Å; L139-V143 HydrophobicContact CD1-CG2 4.18Å; L139-V143 WeakPolarHBondContact O-CB 3.4Å; L139-V143 WeakPolarHBondContact O-CG2 3.42Å; L139-V143 PolarHBondContact O-N 2.91Å
140	T	90.6	Very high	83.6	Confident	33 Å²	33	47.8 Å²	47.8	20%	0.202	28%	0.284	C	S	.	.	H	α-helix	trans	-62.2	-43.1	177.7	-62	0	0	0	0	111.4	D136 M137 V144 L199	D136-T140 VanDerWaalsContact O-CB 3.28Å; D136-T140 WeakPolarHBondContact O-CB 3.42Å; D136-T140 PolarHBondContact O-N 3.37Å; D136-T140 PolarHBondContact O-OG1 3.12Å; M137-T140 PolarHBondContact O-N 3.42Å; T140-V144 HydrophobicContact CG2-CG2 4.24Å; T140-V144 WeakPolarHBondContact O-CB 3.47Å; T140-V144 VanDerWaalsContact O-CG2 3.3Å; T140-V144 WeakPolarHBondContact O-CG2 3.29Å; T140-V144 PolarHBondContact O-N 3.2Å; T140-L199 HydrophobicContact CG2-CD1 4.38Å; T140-L199 HydrophobicContact CG2-CG 4.31Å; T140-L199 WeakPolarHBondContact OG1-CD1 3.24Å
141	Y	90	Very high	84.1	Confident	27 Å²	27	47.2 Å²	47.2	11%	0.106	26%	0.26	C	S	.	.	H	α-helix	trans	-59	-49.9	176	-176.8	-88.7	0	0	0	111.4	Y114 M137 S138 L139 V144 A145 A206	Y114-Y141 HydrophobicContact CD2-CD1 4.23Å; Y114-Y141 AromaticContact CD2-CD2 3.2Å; Y114-Y141 HydrophobicContact CD2-CD2 3.2Å; Y114-Y141 AromaticContact CD2-CE2 3.73Å; Y114-Y141 HydrophobicContact CD2-CE2 3.73Å; Y114-Y141 AromaticContact CD2-CG 3.5Å; Y114-Y141 HydrophobicContact CD2-CG 3.5Å; Y114-Y141 HydrophobicContact CE2-CD1 4.18Å; Y114-Y141 AromaticContact CE2-CD2 3.78Å; Y114-Y141 HydrophobicContact CE2-CD2 3.78Å; Y114-Y141 AromaticContact CE2-CG 3.55Å; Y114-Y141 HydrophobicContact CE2-CG 3.55Å; Y114-Y141 HydrophobicContact CG-CD1 4.47Å; Y114-Y141 AromaticContact CG-CD2 3.69Å; Y114-Y141 HydrophobicContact CG-CD2 3.69Å; Y114-Y141 HydrophobicContact CG-CE1 4.48Å; Y114-Y141 AromaticContact CG-CE2 3.69Å; Y114-Y141 HydrophobicContact CG-CE2 3.69Å; Y114-Y141 HydrophobicContact CG-CG 4.1Å; M137-Y141 WeakPolarHBondContact O-CB 3.45Å; M137-Y141 PolarHBondContact O-N 3.04Å; S138-Y141 PolarHBondContact O-N 3.33Å; L139-Y141 PolarHBondContact O-N 3.03Å; Y141-V144 PolarHBondContact O-N 3.01Å; Y141-A145 WeakPolarHBondContact O-CB 3.11Å; Y141-A145 PolarHBondContact O-N 2.94Å; Y141-A206 HydrophobicContact CD2-CB 3.35Å; Y141-A206 HydrophobicContact CE2-CB 3.77Å; Y141-A206 HydrophobicContact CG-CB 3.93Å
142	I	85.6	Confident	84.2	Confident	54 Å²	54	44.4 Å²	44.4	28%	0.277	24%	0.242	S	C	.	.	H	α-helix	trans	-62.3	-47.5	-179.5	-66.5	163.9	0	0	0	111.4	S138 L139 A145 L146	S138-I142 WeakPolarHBondContact O-CG1 3.42Å; S138-I142 PolarHBondContact O-N 3.07Å; L139-I142 PolarHBondContact O-N 3.25Å; I142-A145 PolarHBondContact O-N 3.13Å; I142-L146 HydrophobicContact CG2-CD1 4.09Å; I142-L146 WeakPolarHBondContact O-CD1 3.32Å; I142-L146 WeakPolarHBondContact O-CG 3.32Å; I142-L146 PolarHBondContact O-N 3.47Å
143	V	87.2	Confident	83.9	Confident	72 Å²	72	43.1 Å²	43.1	44%	0.436	23%	0.23	S	C	.	.	H	α-helix	trans	-64.8	-43.3	-178.9	171.9	0	0	0	0	111.5	L139 L146 L147	L139-V143 HydrophobicContact CD1-CG2 4.18Å; L139-V143 WeakPolarHBondContact O-CB 3.4Å; L139-V143 WeakPolarHBondContact O-CG2 3.42Å; L139-V143 PolarHBondContact O-N 2.91Å; V143-L146 PolarHBondContact O-N 2.94Å; V143-L147 WeakPolarHBondContact O-CG 3.42Å; V143-L147 PolarHBondContact O-N 3.02Å
144	V	92.4	Very high	83.4	Confident	35 Å²	35	45.8 Å²	45.8	21%	0.212	25%	0.247	C	C	.	.	H	α-helix	trans	-73	-37.5	179.5	178.5	0	0	0	0	111.5	T140 Y141 L146 L147 A148 G203 A206 F207	T140-V144 HydrophobicContact CG2-CG2 4.24Å; T140-V144 WeakPolarHBondContact O-CB 3.47Å; T140-V144 VanDerWaalsContact O-CG2 3.3Å; T140-V144 WeakPolarHBondContact O-CG2 3.29Å; T140-V144 PolarHBondContact O-N 3.2Å; Y141-V144 PolarHBondContact O-N 3.01Å; V144-L146 VanDerWaalsContact C-N 3.28Å; V144-L146 PolarHBondContact O-N 3.41Å; V144-L147 PolarHBondContact O-N 3.36Å; V144-A148 VanDerWaalsContact O-CB 3.28Å; V144-A148 WeakPolarHBondContact O-CB 3.4Å; V144-A148 PolarHBondContact O-N 2.6Å; V144-G203 VanDerWaalsContact CG1-O 3.28Å; V144-G203 WeakPolarHBondContact CG1-O 3.17Å; V144-A206 HydrophobicContact CB-CB 4.05Å; V144-A206 HydrophobicContact CG1-CB 4.15Å; V144-F207 HydrophobicContact CG1-CB 3.9Å
145	A	88.8	Confident	83	Confident	6 Å²	6	46 Å²	46	5%	0.05	25%	0.247	C	C	.	.	H	α-helix	trans	-58.5	-39.9	172.3	0	0	0	0	0	111.5	Y141 I142 A148 V149 T210	Y141-A145 WeakPolarHBondContact O-CB 3.11Å; Y141-A145 PolarHBondContact O-N 2.94Å; I142-A145 PolarHBondContact O-N 3.13Å; A145-A148 CarbonylContact O-C 3.59Å; A145-A148 WeakPolarHBondContact O-CB 3.45Å; A145-A148 PolarHBondContact O-N 3.12Å; A145-V149 VanDerWaalsContact O-CG2 3.26Å; A145-V149 WeakPolarHBondContact O-CG2 3.33Å; A145-V149 PolarHBondContact O-N 3.37Å; A145-T210 WeakPolarHBondContact CA-OG1 3.37Å; A145-T210 WeakPolarHBondContact CB-OG1 3.46Å
146	L	82.6	Confident	82.5	Confident	36 Å²	36	42.2 Å²	42.2	19%	0.188	23%	0.231	C	C	.	.	H	α-helix	trans	-63.8	-46.9	175.9	-78.5	164.2	0	0	0	113.4	I142 V143 V144 A148 V149 I150 M521	I142-L146 HydrophobicContact CG2-CD1 4.09Å; I142-L146 WeakPolarHBondContact O-CD1 3.32Å; I142-L146 WeakPolarHBondContact O-CG 3.32Å; I142-L146 PolarHBondContact O-N 3.47Å; V143-L146 PolarHBondContact O-N 2.94Å; V144-L146 VanDerWaalsContact C-N 3.28Å; V144-L146 PolarHBondContact O-N 3.41Å; L146-A148 VanDerWaalsContact C-N 3.27Å; L146-A148 PolarHBondContact O-N 3.25Å; L146-V149 PolarHBondContact O-N 2.99Å; L146-I150 WeakPolarHBondContact O-CG1 3.44Å; L146-I150 PolarHBondContact O-N 3.19Å; L146-I150 VanDerWaalsContact O-N 3.08Å; L146-M521 HydrophobicContact CD1-CB 3.97Å; L146-M521 HydrophobicContact CD1-CE 4.17Å; L146-M521 HydrophobicContact CD1-CG 3.61Å; L146-M521 HydrophobicContact CD1-SD 3.51Å; L146-M521 VanDerWaalsContact CD1-SD 3.51Å; L146-M521 HydrophobicContact CD2-CB 3.81Å; L146-M521 HydrophobicContact CD2-CG 4Å; L146-M521 HydrophobicContact CD2-SD 3.37Å; L146-M521 WeakPolarHBondContact CD2-SD 3.17Å; L146-M521 HydrophobicContact CG-CB 4.29Å; L146-M521 HydrophobicContact CG-CG 4.36Å; L146-M521 HydrophobicContact CG-SD 4.06Å
147	L	87.1	Confident	81.8	Confident	110 Å²	110	43.1 Å²	43.1	58%	0.576	23%	0.234	S	C	*	.	H	α-helix	trans	-61.8	-38.9	174.7	-65.7	173.6	0	0	0	111	V143 V144 I150 L151	V143-L147 WeakPolarHBondContact O-CG 3.42Å; V143-L147 PolarHBondContact O-N 3.02Å; V144-L147 PolarHBondContact O-N 3.36Å; L147-I150 PolarHBondContact O-N 3.32Å; L147-L151 WeakPolarHBondContact O-CB 3.19Å; L147-L151 PolarHBondContact O-N 2.99Å
148	A	88.1	Confident	81.1	Confident	0 Å²	0	49.5 Å²	49.5	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-65	-40.4	175.5	0	0	0	0	0	112.5	V144 A145 L146 L151 N152 F207 T210 V211	V144-A148 VanDerWaalsContact O-CB 3.28Å; V144-A148 WeakPolarHBondContact O-CB 3.4Å; V144-A148 PolarHBondContact O-N 2.6Å; A145-A148 CarbonylContact O-C 3.59Å; A145-A148 WeakPolarHBondContact O-CB 3.45Å; A145-A148 PolarHBondContact O-N 3.12Å; L146-A148 VanDerWaalsContact C-N 3.27Å; L146-A148 PolarHBondContact O-N 3.25Å; A148-L151 PolarHBondContact O-N 3.5Å; A148-N152 WeakPolarHBondContact O-CB 3.2Å; A148-N152 PolarHBondContact O-N 3.22Å; A148-F207 HydrophobicContact CB-CD2 3.63Å; A148-F207 HydrophobicContact CB-CE2 4.09Å; A148-F207 HydrophobicContact CB-CG 4.32Å; A148-T210 HydrophobicContact CB-CG2 3.78Å; A148-V211 HydrophobicContact CB-CG2 4.5Å
149	V	79.7	Confident	80.9	Confident	9 Å²	9	51.8 Å²	51.8	6%	0.055	27%	0.267	C	S	.	.	H	α-helix	trans	-61.7	-45.6	174.5	167.8	0	0	0	0	111.5	A145 L146 N152 N153 T210 V514 M517	A145-V149 VanDerWaalsContact O-CG2 3.26Å; A145-V149 WeakPolarHBondContact O-CG2 3.33Å; A145-V149 PolarHBondContact O-N 3.37Å; L146-V149 PolarHBondContact O-N 2.99Å; V149-N152 WeakPolarHBondContact O-CB 3.44Å; V149-N152 PolarHBondContact O-N 3.34Å; V149-N153 PolarHBondContact O-ND2 3Å; V149-T210 HydrophobicContact CG2-CG2 3.56Å; V149-V514 HydrophobicContact CG1-CB 4.07Å; V149-V514 HydrophobicContact CG1-CG1 3.81Å; V149-V514 HydrophobicContact CG1-CG2 3.95Å; V149-M517 HydrophobicContact CG2-CB 3.61Å; V149-M517 HydrophobicContact CG2-CG 3.64Å
150	I	79.2	Confident	80.8	Confident	115 Å²	115	51 Å²	51	59%	0.59	27%	0.269	S	S	*	.	H	α-helix	trans	-63.1	-48.2	178.1	-65.3	168.2	0	0	0	109.8	L146 L147 N152 N153	L146-I150 WeakPolarHBondContact O-CG1 3.44Å; L146-I150 PolarHBondContact O-N 3.19Å; L146-I150 VanDerWaalsContact O-N 3.08Å; L147-I150 PolarHBondContact O-N 3.32Å; I150-N152 VanDerWaalsContact C-N 3.28Å; I150-N152 PolarHBondContact O-N 3.29Å; I150-N153 WeakPolarHBondContact O-CB 3.02Å; I150-N153 PolarHBondContact O-N 3.1Å; I150-N153 PolarHBondContact O-ND2 3.32Å
151	L	81.3	Confident	80.3	Confident	78 Å²	78	49.9 Å²	49.9	41%	0.408	26%	0.262	S	S	.	.	H	α-helix	trans	-66.2	-29.5	178.4	-168.9	66.4	0	0	0	112.6	L147 A148 N153 V154 L155 F207	L147-L151 WeakPolarHBondContact O-CB 3.19Å; L147-L151 PolarHBondContact O-N 2.99Å; A148-L151 PolarHBondContact O-N 3.5Å; L151-N153 PolarHBondContact O-N 3.4Å; L151-V154 WeakPolarHBondContact O-CA 3.42Å; L151-V154 WeakPolarHBondContact O-CB 3.48Å; L151-V154 PolarHBondContact O-N 3.48Å; L151-L155 HydrophobicContact CB-CD1 4.47Å; L151-L155 HydrophobicContact CD2-CD1 4.07Å; L151-L155 HydrophobicContact CG-CD1 3.91Å; L151-L155 HydrophobicContact CG-CG 4.14Å; L151-L155 WeakPolarHBondContact O-CG 3.41Å; L151-L155 PolarHBondContact O-N 3.37Å; L151-F207 HydrophobicContact CD2-CE2 3.81Å; L151-F207 HydrophobicContact CD2-CZ 3.96Å
152	N	77	Confident	80	Confident	1 Å²	1	51 Å²	51	1%	0.005	27%	0.268	C	S	.	.	H	α-helix	trans	-60.8	-30.6	178	-173.3	59.9	0	0	0	111.9	A148 V149 I150 V154 L155 V156 S214	A148-N152 WeakPolarHBondContact O-CB 3.2Å; A148-N152 PolarHBondContact O-N 3.22Å; V149-N152 WeakPolarHBondContact O-CB 3.44Å; V149-N152 PolarHBondContact O-N 3.34Å; I150-N152 VanDerWaalsContact C-N 3.28Å; I150-N152 PolarHBondContact O-N 3.29Å; N152-V154 PolarHBondContact O-N 2.89Å; N152-L155 PolarHBondContact O-N 3.19Å; N152-V156 WeakPolarHBondContact O-CB 3.07Å; N152-V156 WeakPolarHBondContact O-CG2 2.89Å; N152-V156 PolarHBondContact O-N 3.36Å; N152-S214 VanDerWaalsContact ND2-CB 3.33Å; N152-S214 WeakPolarHBondContact ND2-CB 3.33Å; N152-S214 PolarHBondContact ND2-OG 2.88Å
153	N	71.3	Confident	79.9	Confident	39 Å²	39	51.8 Å²	51.8	21%	0.209	28%	0.275	C	S	.	.	H	α-helix	trans	-57.2	-38.2	171.5	-64	-63.8	0	0	0	112.3	V149 I150 L151 R371	V149-N153 PolarHBondContact O-ND2 3Å; I150-N153 WeakPolarHBondContact O-CB 3.02Å; I150-N153 PolarHBondContact O-N 3.1Å; I150-N153 PolarHBondContact O-ND2 3.32Å; L151-N153 PolarHBondContact O-N 3.4Å; N153-R371 PolarHBondContact O-NH2 3.06Å; N153-R371 VanDerWaalsContact O-NH2 3.13Å; N153-R371 PolarHBondContact OD1-NH1 2.94Å
154	V	70.6	Confident	80.1	Confident	59 Å²	59	48.6 Å²	48.6	36%	0.358	26%	0.255	S	S	.	.	H	α-helix	trans	-78.2	-42.2	176	-178	0	0	0	0	111.1	L151 N152 V156 R158 M367	L151-V154 WeakPolarHBondContact O-CA 3.42Å; L151-V154 WeakPolarHBondContact O-CB 3.48Å; L151-V154 PolarHBondContact O-N 3.48Å; N152-V154 PolarHBondContact O-N 2.89Å; V154-V156 VanDerWaalsContact C-N 3.35Å; V154-V156 PolarHBondContact O-N 2.9Å; V154-R158 HydrophobicContact CG1-CG 3.97Å; V154-R158 WeakPolarHBondContact O-CB 3.28Å; V154-R158 WeakPolarHBondContact O-CG 3.33Å; V154-R158 PolarHBondContact O-N 2.74Å; V154-R158 VanDerWaalsContact O-N 3.15Å; V154-M367 HydrophobicContact CG2-CE 4.34Å
155	L	71.1	Confident	79.9	Confident	33 Å²	33	47 Å²	47	17%	0.173	25%	0.245	C	C	.	.	H	α-helix	trans	-65.5	-34.9	-178.2	-66.7	163.4	0	0	0	112.8	L151 N152 E157 R158 L159 F207 V211	L151-L155 HydrophobicContact CB-CD1 4.47Å; L151-L155 HydrophobicContact CD2-CD1 4.07Å; L151-L155 HydrophobicContact CG-CD1 3.91Å; L151-L155 HydrophobicContact CG-CG 4.14Å; L151-L155 WeakPolarHBondContact O-CG 3.41Å; L151-L155 PolarHBondContact O-N 3.37Å; N152-L155 PolarHBondContact O-N 3.19Å; L155-E157 VanDerWaalsContact C-N 3.26Å; L155-E157 PolarHBondContact O-N 3.26Å; L155-R158 PolarHBondContact O-N 3Å; L155-L159 HydrophobicContact CD2-CD1 3.68Å; L155-L159 HydrophobicContact CD2-CG 4.41Å; L155-L159 WeakPolarHBondContact O-CB 3.39Å; L155-L159 PolarHBondContact O-N 3.37Å; L155-F207 HydrophobicContact CD1-CZ 4.3Å; L155-V211 HydrophobicContact CD1-CG1 4.48Å; L155-V211 HydrophobicContact CD1-CG2 3.98Å
156	V	70.5	Confident	79.9	Confident	14 Å²	14	48.1 Å²	48.1	9%	0.085	25%	0.252	C	S	.	.	H	α-helix	trans	-56	-42.4	-178.9	163.4	0	0	0	0	111.7	N152 V154 R164 N510	N152-V156 WeakPolarHBondContact O-CB 3.07Å; N152-V156 WeakPolarHBondContact O-CG2 2.89Å; N152-V156 PolarHBondContact O-N 3.36Å; V154-V156 VanDerWaalsContact C-N 3.35Å; V154-V156 PolarHBondContact O-N 2.9Å; V156-R164 PolarHBondContact O-NH2 3.44Å; V156-N510 HydrophobicContact CG2-CB 4.34Å
157	E	69.8	Low	80.3	Confident	66 Å²	66	49.6 Å²	49.6	31%	0.308	26%	0.262	S	S	.	.	H	α-helix	trans	-94.1	-18.4	-176	-69.1	164.5	-130.3	0	0	112.7	L155 M367 R371	L155-E157 VanDerWaalsContact C-N 3.26Å; L155-E157 PolarHBondContact O-N 3.26Å; E157-M367 VanDerWaalsContact OE1-CG 3.32Å; E157-M367 WeakPolarHBondContact OE1-CG 3.33Å; E157-M367 VanDerWaalsContact OE2-CB 3.23Å; E157-M367 WeakPolarHBondContact OE2-CB 3.33Å; E157-M367 WeakPolarHBondContact OE2-CG 3.48Å; E157-R371 IonicContact OE1-CZ 3.5Å; E157-R371 VanDerWaalsContact OE1-CZ 3.22Å; E157-R371 IonicContact OE1-NE 2.7Å; E157-R371 PolarHBondContact OE1-NE 3.13Å; E157-R371 IonicContact OE1-NH2 3.42Å; E157-R371 PolarHBondContact OE1-NH2 3.39Å
158	R	71.6	Confident	80.5	Confident	135 Å²	135	44.4 Å²	44.4	51%	0.509	24%	0.235	S	C	.	.	H	α-helix	trans	-85.6	-33.6	176.3	-68.1	-89.9	178	153.6	0.2	113.6	V154 L155 W361	V154-R158 HydrophobicContact CG1-CG 3.97Å; V154-R158 WeakPolarHBondContact O-CB 3.28Å; V154-R158 WeakPolarHBondContact O-CG 3.33Å; V154-R158 PolarHBondContact O-N 2.74Å; V154-R158 VanDerWaalsContact O-N 3.15Å; L155-R158 PolarHBondContact O-N 3Å; R158-W361 HydrophobicContact CB-CZ3 4.4Å; R158-W361 HydrophobicContact CG-CZ3 4.3Å
159	L	79.8	Confident	80.7	Confident	78 Å²	78	44.4 Å²	44.4	41%	0.408	24%	0.235	S	C	.	.	S	Bend	trans	-125.2	141.9	-171	-59.7	-179.5	0	0	0	112	L155 M161 R164	L155-L159 HydrophobicContact CD2-CD1 3.68Å; L155-L159 HydrophobicContact CD2-CG 4.41Å; L155-L159 WeakPolarHBondContact O-CB 3.39Å; L155-L159 PolarHBondContact O-N 3.37Å; L159-M161 PolarHBondContact O-N 2.9Å; L159-R164 HydrophobicContact CB-CG 3.82Å; L159-R164 HydrophobicContact CD1-CG 4.41Å; L159-R164 PolarHBondContact O-NE 3.08Å; L159-R164 PolarHBondContact O-NH2 3.06Å
160	S	82.1	Confident	81.3	Confident	70 Å²	70	48.7 Å²	48.7	49%	0.49	26%	0.257	S	S	.	.			trans	-58.1	135.1	172.4	-178	0	0	0	0	111.1	H162 T163 R164	S160-H162 PolarHBondContact O-N 3.32Å; S160-T163 WeakPolarHBondContact O-CA 3.39Å; S160-T163 WeakPolarHBondContact O-CB 3.48Å; S160-T163 PolarHBondContact O-N 3.03Å; S160-R164 PolarHBondContact O-N 3Å
161	M	80.6	Confident	82	Confident	10 Å²	10	45.6 Å²	45.6	5%	0.049	24%	0.241	C	C	.	.	H	α-helix	trans	-45.2	-43.9	174.3	-177.2	-162.4	83	0	0	113.2	L159 T163 R164 I165 Y219 M222	L159-M161 PolarHBondContact O-N 2.9Å; M161-T163 PolarHBondContact O-N 3.36Å; M161-R164 PolarHBondContact O-N 2.83Å; M161-I165 HydrophobicContact CG-CD1 4.09Å; M161-I165 WeakPolarHBondContact O-CG1 3.43Å; M161-I165 PolarHBondContact O-N 2.86Å; M161-Y219 HydrophobicContact CE-CD2 3.34Å; M161-Y219 HydrophobicContact CE-CE2 3.97Å; M161-Y219 HydrophobicContact CE-CG 3.71Å; M161-Y219 WeakPolarHBondContact SD-CB 3.46Å; M161-Y219 HydrophobicContact SD-CD2 3.7Å; M161-Y219 HydrophobicContact SD-CG 3.82Å; M161-M222 HydrophobicContact SD-SD 4.46Å
162	H	82.8	Confident	82.5	Confident	52 Å²	52	41.9 Å²	41.9	24%	0.241	22%	0.222	C	C	.	.	H	α-helix	trans	-66.9	-35.3	177.9	-65.1	-51.3	0	0	0	113.2	S160 T166	S160-H162 PolarHBondContact O-N 3.32Å; H162-T166 VanDerWaalsContact O-CB 3.31Å; H162-T166 WeakPolarHBondContact O-CB 3.45Å; H162-T166 PolarHBondContact O-N 2.93Å; H162-T166 PolarHBondContact O-OG1 3Å
163	T	85.3	Confident	83.3	Confident	69 Å²	69	42.5 Å²	42.5	42%	0.423	23%	0.225	S	C	.	.	H	α-helix	trans	-67.1	-45.5	174.1	-53.7	0	0	0	0	110.1	S160 M161 I165 T166 V167	S160-T163 WeakPolarHBondContact O-CA 3.39Å; S160-T163 WeakPolarHBondContact O-CB 3.48Å; S160-T163 PolarHBondContact O-N 3.03Å; M161-T163 PolarHBondContact O-N 3.36Å; T163-I165 PolarHBondContact O-N 3.09Å; T163-T166 PolarHBondContact O-N 3.23Å; T163-V167 HydrophobicContact CG2-CG2 4.23Å; T163-V167 WeakPolarHBondContact O-CB 3.48Å; T163-V167 VanDerWaalsContact O-CG2 3.3Å; T163-V167 WeakPolarHBondContact O-CG2 3.37Å; T163-V167 PolarHBondContact O-N 3.37Å
164	R	89.7	Confident	84.3	Confident	6 Å²	6	42.4 Å²	42.4	2%	0.023	23%	0.233	C	C	.	.	H	α-helix	trans	-56.9	-49.3	177.6	-69.3	-176.7	-92.7	128	-13.2	112.1	V156 L159 S160 M161 G168 V211 S215 E506	V156-R164 PolarHBondContact O-NH2 3.44Å; L159-R164 HydrophobicContact CB-CG 3.82Å; L159-R164 HydrophobicContact CD1-CG 4.41Å; L159-R164 PolarHBondContact O-NE 3.08Å; L159-R164 PolarHBondContact O-NH2 3.06Å; S160-R164 PolarHBondContact O-N 3Å; M161-R164 PolarHBondContact O-N 2.83Å; R164-G168 PolarHBondContact O-N 2.94Å; R164-V211 HydrophobicContact CB-CG1 4.16Å; R164-V211 HydrophobicContact CG-CG1 4.49Å; R164-S215 VanDerWaalsContact CB-OG 3.28Å; R164-S215 WeakPolarHBondContact CB-OG 3.15Å; R164-S215 WeakPolarHBondContact CD-OG 3.49Å; R164-S215 PolarHBondContact NH1-OG 3.4Å; R164-E506 IonicContact CZ-OE1 3.66Å; R164-E506 IonicContact NH1-OE1 2.78Å; R164-E506 IonicContact NH2-OE1 2.82Å; R164-E506 PolarHBondContact NH2-OE1 3.28Å
165	I	88.7	Confident	85.4	Confident	0 Å²	0	40.3 Å²	40.3	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-64.9	-44.2	178.3	-62.8	165	0	0	0	111.3	M161 T163 V167 G168 Y169 Q212 F216 Y219 H278	M161-I165 HydrophobicContact CG-CD1 4.09Å; M161-I165 WeakPolarHBondContact O-CG1 3.43Å; M161-I165 PolarHBondContact O-N 2.86Å; T163-I165 PolarHBondContact O-N 3.09Å; I165-V167 PolarHBondContact O-N 2.93Å; I165-G168 PolarHBondContact O-N 2.82Å; I165-Y169 HydrophobicContact CG2-CD2 3.84Å; I165-Y169 HydrophobicContact CG2-CE2 3.65Å; I165-Y169 VanDerWaalsContact O-CD2 3.32Å; I165-Y169 WeakPolarHBondContact O-CD2 3.37Å; I165-Y169 PolarHBondContact O-N 2.85Å; I165-Y169 VanDerWaalsContact O-N 3.13Å; I165-Q212 HydrophobicContact CG2-CG 4.47Å; I165-F216 HydrophobicContact CD1-CD2 3.94Å; I165-F216 HydrophobicContact CG1-CD2 4.36Å; I165-F216 HydrophobicContact CG2-CD2 4.15Å; I165-Y219 HydrophobicContact CD1-CD1 4.43Å; I165-H278 WeakPolarHBondContact CG2-NE2 3.18Å
166	T	89.3	Confident	86.3	Confident	31 Å²	31	38.7 Å²	38.7	19%	0.19	21%	0.213	C	C	.	.	H	α-helix	trans	-63.5	-42.7	179.7	-55.6	0	0	0	0	111.9	H162 T163 Y169 I170 F275	H162-T166 VanDerWaalsContact O-CB 3.31Å; H162-T166 WeakPolarHBondContact O-CB 3.45Å; H162-T166 PolarHBondContact O-N 2.93Å; H162-T166 PolarHBondContact O-OG1 3Å; T163-T166 PolarHBondContact O-N 3.23Å; T166-Y169 PolarHBondContact O-N 2.92Å; T166-I170 HydrophobicContact CG2-CD1 4.25Å; T166-I170 WeakPolarHBondContact O-CG1 3.2Å; T166-I170 PolarHBondContact O-N 3.18Å; T166-F275 HydrophobicContact CG2-CE2 4.14Å
167	V	90.9	Very high	87.4	Confident	67 Å²	67	41.1 Å²	41.1	41%	0.406	22%	0.224	S	C	.	.	H	α-helix	trans	-65.5	-41.4	176.9	169.2	0	0	0	0	110.7	T163 I165 Y169 I170 L171	T163-V167 HydrophobicContact CG2-CG2 4.23Å; T163-V167 WeakPolarHBondContact O-CB 3.48Å; T163-V167 VanDerWaalsContact O-CG2 3.3Å; T163-V167 WeakPolarHBondContact O-CG2 3.37Å; T163-V167 PolarHBondContact O-N 3.37Å; I165-V167 PolarHBondContact O-N 2.93Å; V167-Y169 PolarHBondContact O-N 3.21Å; V167-I170 PolarHBondContact O-N 2.89Å; V167-L171 HydrophobicContact CG1-CD1 3.87Å; V167-L171 HydrophobicContact CG1-CG 4.21Å; V167-L171 WeakPolarHBondContact O-CG 3.49Å; V167-L171 PolarHBondContact O-N 3.33Å
168	G	91.7	Very high	88.5	Confident	1 Å²	1	41.8 Å²	41.8	1%	0.01	23%	0.226	C	C	.	.	H	α-helix	trans	-54	-50.1	174.5	0	0	0	0	0	113	R164 I165 I170 L171 A172 G208 Q212	R164-G168 PolarHBondContact O-N 2.94Å; I165-G168 PolarHBondContact O-N 2.82Å; G168-I170 VanDerWaalsContact C-N 3.29Å; G168-I170 PolarHBondContact O-N 3.43Å; G168-L171 CarbonylContact O-C 3.09Å; G168-L171 PolarHBondContact O-N 3.44Å; G168-L171 VanDerWaalsContact O-N 3.07Å; G168-A172 PolarHBondContact O-N 2.89Å; G168-G208 WeakPolarHBondContact CA-O 3.43Å; G168-Q212 PolarHBondContact O-OE1 2.94Å
169	Y	91.9	Very high	89.4	Confident	0 Å²	0	35.4 Å²	35.4	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-60.6	-38.9	179.5	-86	-69.2	0	0	0	111.8	I165 T166 V167 A172 L173 Q212 E271 C274 F275 H278	I165-Y169 HydrophobicContact CG2-CD2 3.84Å; I165-Y169 HydrophobicContact CG2-CE2 3.65Å; I165-Y169 VanDerWaalsContact O-CD2 3.32Å; I165-Y169 WeakPolarHBondContact O-CD2 3.37Å; I165-Y169 PolarHBondContact O-N 2.85Å; I165-Y169 VanDerWaalsContact O-N 3.13Å; T166-Y169 PolarHBondContact O-N 2.92Å; V167-Y169 PolarHBondContact O-N 3.21Å; Y169-A172 PolarHBondContact O-N 2.99Å; Y169-L173 VanDerWaalsContact O-CB 3.32Å; Y169-L173 WeakPolarHBondContact O-CB 3.49Å; Y169-L173 WeakPolarHBondContact O-CG 3.31Å; Y169-L173 PolarHBondContact O-N 3.44Å; Y169-Q212 VanDerWaalsContact CA-OE1 3.27Å; Y169-Q212 VanDerWaalsContact CZ-NE2 3.28Å; Y169-E271 HydrophobicContact CD1-CG 4.39Å; Y169-E271 WeakPolarHBondContact CD1-OE1 3.43Å; Y169-E271 VanDerWaalsContact CE1-OE1 3.26Å; Y169-E271 WeakPolarHBondContact CE1-OE1 3.48Å; Y169-C274 HydrophobicContact CE1-CB 3.78Å; Y169-F275 VanDerWaalsContact CB-CD2 3.48Å; Y169-F275 HydrophobicContact CD1-CB 3.96Å; Y169-F275 HydrophobicContact CD1-CD2 4.34Å; Y169-F275 AromaticContact CD2-CD2 3.89Å; Y169-F275 HydrophobicContact CD2-CD2 3.89Å; Y169-F275 HydrophobicContact CE1-CB 4.37Å; Y169-F275 HydrophobicContact CG-CB 4.16Å; Y169-F275 AromaticContact CG-CD2 3.67Å; Y169-F275 HydrophobicContact CG-CD2 3.67Å; Y169-F275 HydrophobicContact CG-CG 4.38Å; Y169-H278 HydrophobicContact CE2-CB 4Å
170	I	92.6	Very high	89.8	Confident	99 Å²	99	31.8 Å²	31.8	51%	0.508	18%	0.183	S	C	.	.	H	α-helix	trans	-66.6	-40.3	176.8	-66.5	166.1	0	0	0	111	T166 V167 G168 A172 G174	T166-I170 HydrophobicContact CG2-CD1 4.25Å; T166-I170 WeakPolarHBondContact O-CG1 3.2Å; T166-I170 PolarHBondContact O-N 3.18Å; V167-I170 PolarHBondContact O-N 2.89Å; G168-I170 VanDerWaalsContact C-N 3.29Å; G168-I170 PolarHBondContact O-N 3.43Å; I170-A172 VanDerWaalsContact C-N 3.31Å; I170-G174 PolarHBondContact O-N 2.93Å
171	L	93.8	Very high	90.2	Very high	50 Å²	50	31.4 Å²	31.4	26%	0.262	18%	0.176	S	C	.	.	H	α-helix	trans	-73	-20	177	-65.5	179.8	0	0	0	113.3	V167 G168 P175 V204 F207	V167-L171 HydrophobicContact CG1-CD1 3.87Å; V167-L171 HydrophobicContact CG1-CG 4.21Å; V167-L171 WeakPolarHBondContact O-CG 3.49Å; V167-L171 PolarHBondContact O-N 3.33Å; G168-L171 CarbonylContact O-C 3.09Å; G168-L171 PolarHBondContact O-N 3.44Å; G168-L171 VanDerWaalsContact O-N 3.07Å; L171-P175 WeakPolarHBondContact O-CD 3.43Å; L171-P175 VanDerWaalsContact O-CG 3.3Å; L171-P175 WeakPolarHBondContact O-CG 3.47Å; L171-V204 HydrophobicContact CB-CG1 4.17Å; L171-V204 HydrophobicContact CD2-CG1 3.92Å; L171-F207 HydrophobicContact CD1-CD1 3.89Å; L171-F207 HydrophobicContact CD1-CE1 4.26Å
172	A	91.8	Very high	90.6	Very high	0 Å²	0	34.4 Å²	34.4	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-81.1	-51.5	169.2	0	0	0	0	0	111.9	P113 G168 Y169 I170 L176	P113-A172 HydrophobicContact CB-CB 4.2Å; P113-A172 HydrophobicContact CG-CB 3.97Å; G168-A172 PolarHBondContact O-N 2.89Å; Y169-A172 PolarHBondContact O-N 2.99Å; I170-A172 VanDerWaalsContact C-N 3.31Å; A172-L176 WeakPolarHBondContact O-CD1 3.44Å; A172-L176 WeakPolarHBondContact O-CG 3.37Å
173	L	92.6	Very high	90.7	Very high	13 Å²	13	32 Å²	32	7%	0.068	18%	0.178	C	C	.	.	H	α-helix	trans	-67.5	-41.5	-176.3	-76.9	164.2	0	0	0	113.7	Y169 L176 I177 E271 M272 F275	Y169-L173 VanDerWaalsContact O-CB 3.32Å; Y169-L173 WeakPolarHBondContact O-CB 3.49Å; Y169-L173 WeakPolarHBondContact O-CG 3.31Å; Y169-L173 PolarHBondContact O-N 3.44Å; L173-L176 PolarHBondContact O-N 2.96Å; L173-I177 WeakPolarHBondContact O-CG1 3.28Å; L173-I177 PolarHBondContact O-N 3.35Å; L173-E271 HydrophobicContact CD1-CG 4.43Å; L173-E271 HydrophobicContact CD2-CB 3.74Å; L173-E271 HydrophobicContact CD2-CG 3.63Å; L173-E271 HydrophobicContact CG-CB 4.41Å; L173-E271 HydrophobicContact CG-CG 3.73Å; L173-M272 HydrophobicContact CD1-SD 3.62Å; L173-M272 HydrophobicContact CD2-CG 3.81Å; L173-M272 HydrophobicContact CD2-SD 3.85Å; L173-M272 HydrophobicContact CG-SD 4.35Å; L173-F275 HydrophobicContact CD1-CB 4.3Å; L173-F275 HydrophobicContact CD1-CG 4.48Å
174	G	93.6	Very high	90.7	Very high	38 Å²	38	28.9 Å²	28.9	39%	0.392	16%	0.158	S	C	.	.	H	α-helix	trans	-57.2	-55.5	-175.8	0	0	0	0	0	113.1	I170 I177 F178	I170-G174 PolarHBondContact O-N 2.93Å; G174-I177 PolarHBondContact O-N 2.87Å; G174-F178 WeakPolarHBondContact O-CB 3.38Å; G174-F178 PolarHBondContact O-N 2.9Å
175	P	93.2	Very high	90.5	Very high	14 Å²	14	36 Å²	36	9%	0.091	19%	0.185	C	C	.	.	H	α-helix	trans	-65.8	-35.4	178.3	-22.6	34.8	0	0	0	113.8	L171 F178 V179 V204 V205	L171-P175 WeakPolarHBondContact O-CD 3.43Å; L171-P175 VanDerWaalsContact O-CG 3.3Å; L171-P175 WeakPolarHBondContact O-CG 3.47Å; P175-F178 PolarHBondContact O-N 3.47Å; P175-V179 WeakPolarHBondContact O-CB 3.3Å; P175-V179 PolarHBondContact O-N 2.86Å; P175-V204 HydrophobicContact CG-CB 4.04Å; P175-V204 HydrophobicContact CG-CG1 3.73Å; P175-V205 HydrophobicContact CB-CG2 3.76Å; P175-V205 HydrophobicContact CG-CG2 3.91Å
176	L	91	Very high	90.3	Very high	0 Å²	0	40.1 Å²	40.1	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-58.8	-51.6	174.3	-76.6	172.2	0	0	0	111.6	P113 F117 A172 L173 F178 S180 F264 I268	P113-L176 HydrophobicContact CB-CD1 3.91Å; P113-L176 HydrophobicContact CB-CG 4.44Å; P113-L176 HydrophobicContact CG-CD1 4.18Å; F117-L176 HydrophobicContact CD2-CD2 4.29Å; F117-L176 HydrophobicContact CE2-CD2 3.57Å; F117-L176 HydrophobicContact CE2-CG 4.24Å; F117-L176 HydrophobicContact CZ-CD2 4.07Å; A172-L176 WeakPolarHBondContact O-CD1 3.44Å; A172-L176 WeakPolarHBondContact O-CG 3.37Å; L173-L176 PolarHBondContact O-N 2.96Å; L176-F178 VanDerWaalsContact C-N 3.33Å; L176-F178 PolarHBondContact O-N 3.07Å; L176-S180 WeakPolarHBondContact O-CB 3.21Å; L176-S180 PolarHBondContact O-N 3.31Å; L176-F264 HydrophobicContact CD2-CD1 4.06Å; L176-F264 HydrophobicContact CD2-CE1 3.93Å; L176-I268 HydrophobicContact CB-CD1 4.42Å; L176-I268 HydrophobicContact CB-CG1 3.93Å
177	I	92.8	Very high	90.1	Very high	64 Å²	64	43.3 Å²	43.3	33%	0.328	22%	0.22	S	C	.	.	H	α-helix	trans	-63.3	-42.7	178	-66.6	166.9	0	0	0	109.9	L173 G174 L181 I268	L173-I177 WeakPolarHBondContact O-CG1 3.28Å; L173-I177 PolarHBondContact O-N 3.35Å; G174-I177 PolarHBondContact O-N 2.87Å; I177-L181 HydrophobicContact CG2-CD1 3.67Å; I177-L181 HydrophobicContact CG2-CG 4.21Å; I177-L181 WeakPolarHBondContact O-CB 3.31Å; I177-L181 VanDerWaalsContact O-CG 3.23Å; I177-L181 WeakPolarHBondContact O-CG 3.39Å; I177-L181 PolarHBondContact O-N 3.33Å; I177-I268 HydrophobicContact CD1-CG2 4.34Å; I177-I268 HydrophobicContact CG1-CD1 3.98Å; I177-I268 HydrophobicContact CG1-CG1 4.16Å; I177-I268 HydrophobicContact CG1-CG2 3.95Å
178	F	92.9	Very high	89.8	Confident	80 Å²	80	47 Å²	47	35%	0.351	23%	0.23	S	C	.	.	H	α-helix	trans	-61.6	-50.5	-179.7	-177.3	-97.2	0	0	0	112.6	G174 P175 L176 F182 F189 I197	G174-F178 WeakPolarHBondContact O-CB 3.38Å; G174-F178 PolarHBondContact O-N 2.9Å; P175-F178 PolarHBondContact O-N 3.47Å; L176-F178 VanDerWaalsContact C-N 3.33Å; L176-F178 PolarHBondContact O-N 3.07Å; F178-F182 AromaticContact CD2-CD2 3.41Å; F178-F182 HydrophobicContact CD2-CD2 3.41Å; F178-F182 VanDerWaalsContact CD2-CD2 3.41Å; F178-F182 AromaticContact CD2-CE2 3.75Å; F178-F182 HydrophobicContact CD2-CE2 3.75Å; F178-F182 HydrophobicContact CD2-CG 4.39Å; F178-F182 AromaticContact CE2-CD2 3.57Å; F178-F182 HydrophobicContact CE2-CD2 3.57Å; F178-F182 AromaticContact CE2-CE2 3.96Å; F178-F182 HydrophobicContact CE2-CE2 3.96Å; F178-F182 HydrophobicContact CE2-CG 4.18Å; F178-F182 HydrophobicContact CG-CD2 4.08Å; F178-F182 HydrophobicContact CZ-CD2 4.34Å; F178-F182 WeakPolarHBondContact O-CB 3.32Å; F178-F182 WeakPolarHBondContact O-CD2 3.3Å; F178-F182 PolarHBondContact O-N 3.26Å; F178-F189 HydrophobicContact CE1-CE2 4.26Å; F178-F189 HydrophobicContact CE1-CZ 4.41Å; F178-F189 HydrophobicContact CZ-CE2 4.19Å; F178-F189 AromaticContact CZ-CZ 3.95Å; F178-F189 HydrophobicContact CZ-CZ 3.95Å; F178-I197 HydrophobicContact CD1-CG2 4.32Å; F178-I197 HydrophobicContact CE1-CG2 3.73Å
179	V	90.4	Very high	89.4	Confident	1 Å²	1	49.6 Å²	49.6	1%	0.006	24%	0.241	C	C	.	.	I	π-helix	trans	-67.9	-44.7	-179.7	167.5	0	0	0	0	111.3	F117 P175 L181 D183 V184 N198 S201 F264	F117-V179 HydrophobicContact CE1-CB 4.01Å; F117-V179 HydrophobicContact CE1-CG1 3.98Å; F117-V179 HydrophobicContact CE1-CG2 3.95Å; F117-V179 HydrophobicContact CZ-CG2 4.49Å; P175-V179 WeakPolarHBondContact O-CB 3.3Å; P175-V179 PolarHBondContact O-N 2.86Å; V179-L181 VanDerWaalsContact C-N 3.35Å; V179-L181 PolarHBondContact O-N 2.83Å; V179-D183 HydrophobicContact CG1-CB 4.19Å; V179-D183 WeakPolarHBondContact O-CA 3.34Å; V179-D183 WeakPolarHBondContact O-CB 3.38Å; V179-D183 PolarHBondContact O-N 3.38Å; V179-V184 HydrophobicContact CG1-CG2 4.42Å; V179-V184 PolarHBondContact O-N 2.81Å; V179-N198 WeakPolarHBondContact CG1-OD1 3.47Å; V179-S201 WeakPolarHBondContact CG2-OG 3.49Å; V179-F264 HydrophobicContact CG1-CZ 4.31Å
180	S	89.2	Confident	89.2	Confident	2 Å²	2	54.1 Å²	54.1	1%	0.014	27%	0.269	C	S	.	.	I	π-helix	trans	-57.5	-45.8	177.6	-177.9	0	0	0	0	112.1	L176 W185	L176-S180 WeakPolarHBondContact O-CB 3.21Å; L176-S180 PolarHBondContact O-N 3.31Å; S180-W185 WeakPolarHBondContact O-CB 3.19Å; S180-W185 PolarHBondContact O-N 2.96Å
181	L	90.1	Very high	88.8	Confident	63 Å²	63	53.1 Å²	53.1	33%	0.33	27%	0.267	S	S	.	.	I	π-helix	trans	-75.1	-52	179.8	-65.1	-178.8	0	0	0	113	I177 V179 W185 L186	I177-L181 HydrophobicContact CG2-CD1 3.67Å; I177-L181 HydrophobicContact CG2-CG 4.21Å; I177-L181 WeakPolarHBondContact O-CB 3.31Å; I177-L181 VanDerWaalsContact O-CG 3.23Å; I177-L181 WeakPolarHBondContact O-CG 3.39Å; I177-L181 PolarHBondContact O-N 3.33Å; V179-L181 VanDerWaalsContact C-N 3.35Å; V179-L181 PolarHBondContact O-N 2.83Å; L181-W185 HydrophobicContact CD2-CE3 3.58Å; L181-W185 HydrophobicContact CD2-CZ3 3.79Å; L181-L186 VanDerWaalsContact O-CB 3.31Å; L181-L186 WeakPolarHBondContact O-CB 3.49Å; L181-L186 WeakPolarHBondContact O-CG 3.46Å; L181-L186 PolarHBondContact O-N 2.87Å
182	F	88.3	Confident	88.5	Confident	72 Å²	72	59.3 Å²	59.3	32%	0.316	29%	0.292	S	S	.	.	I	π-helix	trans	-90.8	-32	-167.3	-67.1	-77.3	0	0	0	114.5	F178 L186 E187 K188 F189	F178-F182 AromaticContact CD2-CD2 3.41Å; F178-F182 HydrophobicContact CD2-CD2 3.41Å; F178-F182 VanDerWaalsContact CD2-CD2 3.41Å; F178-F182 AromaticContact CD2-CE2 3.75Å; F178-F182 HydrophobicContact CD2-CE2 3.75Å; F178-F182 HydrophobicContact CD2-CG 4.39Å; F178-F182 AromaticContact CE2-CD2 3.57Å; F178-F182 HydrophobicContact CE2-CD2 3.57Å; F178-F182 AromaticContact CE2-CE2 3.96Å; F178-F182 HydrophobicContact CE2-CE2 3.96Å; F178-F182 HydrophobicContact CE2-CG 4.18Å; F178-F182 HydrophobicContact CG-CD2 4.08Å; F178-F182 HydrophobicContact CZ-CD2 4.34Å; F178-F182 WeakPolarHBondContact O-CB 3.32Å; F178-F182 WeakPolarHBondContact O-CD2 3.3Å; F178-F182 PolarHBondContact O-N 3.26Å; F182-L186 HydrophobicContact CD1-CD1 4.07Å; F182-L186 HydrophobicContact CE1-CD1 4.34Å; F182-E187 PolarHBondContact O-N 3.29Å; F182-K188 HydrophobicContact CD1-CD 4.46Å; F182-K188 PolarHBondContact O-N 3.47Å; F182-K188 VanDerWaalsContact O-N 3.13Å; F182-F189 HydrophobicContact CB-CE2 3.71Å; F182-F189 HydrophobicContact CB-CZ 4.31Å
183	D	85.4	Confident	88.3	Confident	2 Å²	2	64.3 Å²	64.3	1%	0.011	32%	0.316	C	S	.	.	I	π-helix	trans	-98.6	-39.1	-176.8	-171.2	49.8	0	0	0	113.2	K127 V179 F189 A194 N198	K127-D183 PolarHBondContact NZ-O 3.03Å; K127-D183 IonicContact NZ-OD1 3.81Å; K127-D183 PolarHBondContact NZ-OD1 3.5Å; K127-D183 IonicContact NZ-OD2 3.43Å; K127-D183 PolarHBondContact NZ-OD2 3.42Å; V179-D183 HydrophobicContact CG1-CB 4.19Å; V179-D183 WeakPolarHBondContact O-CA 3.34Å; V179-D183 WeakPolarHBondContact O-CB 3.38Å; V179-D183 PolarHBondContact O-N 3.38Å; D183-F189 HydrophobicContact CB-CD2 4.34Å; D183-A194 WeakPolarHBondContact OD1-CB 3.41Å; D183-N198 PolarHBondContact OD2-ND2 3.36Å
184	V	84.4	Confident	88	Confident	3 Å²	3	63.7 Å²	63.7	2%	0.018	31%	0.313	C	S	.	.	I	π-helix	trans	-90	-54.2	-179.5	-178	0	0	0	0	112	Y123 V179 K257 T260 F264	Y123-V184 HydrophobicContact CE1-CG2 4.17Å; V179-V184 HydrophobicContact CG1-CG2 4.42Å; V179-V184 PolarHBondContact O-N 2.81Å; V184-K257 WeakPolarHBondContact O-CE 3.36Å; V184-T260 HydrophobicContact CG1-CG2 3.93Å; V184-T260 HydrophobicContact CG2-CG2 4.24Å; V184-F264 HydrophobicContact CG2-CE2 4.4Å
185	W	86.1	Confident	87.8	Confident	156 Å²	156	64.1 Å²	64.1	59%	0.591	30%	0.303	S	S	*	.	I	π-helix	trans	-75.6	-57.1	-177.4	-176.7	5.6	0	0	0	111.9	S180 L181 L261	S180-W185 WeakPolarHBondContact O-CB 3.19Å; S180-W185 PolarHBondContact O-N 2.96Å; L181-W185 HydrophobicContact CD2-CE3 3.58Å; L181-W185 HydrophobicContact CD2-CZ3 3.79Å; W185-L261 HydrophobicContact CB-CD1 4.22Å
186	L	85.5	Confident	87.7	Confident	86 Å²	86	67.3 Å²	67.3	45%	0.45	32%	0.322	S	S	.	.	S	Bend	trans	-86.6	-11.2	-172.5	-63.6	173	0	0	0	115	L181 F182 K188	L181-L186 VanDerWaalsContact O-CB 3.31Å; L181-L186 WeakPolarHBondContact O-CB 3.49Å; L181-L186 WeakPolarHBondContact O-CG 3.46Å; L181-L186 PolarHBondContact O-N 2.87Å; F182-L186 HydrophobicContact CD1-CD1 4.07Å; F182-L186 HydrophobicContact CE1-CD1 4.34Å; L186-K188 HydrophobicContact CB-CG 4.06Å; L186-K188 PolarHBondContact O-N 2.99Å
187	E	83.9	Confident	87.7	Confident	99 Å²	99	68.9 Å²	68.9	46%	0.463	33%	0.33	S	S	.	.			trans	44.3	38.6	178.3	-74.5	170.6	171.8	0	0	114.4	F182 F189 K257	F182-E187 PolarHBondContact O-N 3.29Å; E187-F189 VanDerWaalsContact C-N 3.25Å; E187-F189 PolarHBondContact O-N 2.79Å; E187-K257 VanDerWaalsContact OE1-CE 3.29Å; E187-K257 WeakPolarHBondContact OE1-CE 3.17Å; E187-K257 IonicContact OE1-NZ 3.88Å; E187-K257 PolarHBondContact OE1-NZ 3.12Å; E187-K257 IonicContact OE2-NZ 2.76Å; E187-K257 PolarHBondContact OE2-NZ 3.19Å
188	K	83.9	Confident	87.6	Confident	143 Å²	143	66 Å²	66	62%	0.622	32%	0.315	S	S	*	.			trans	-74.2	-11.4	-172.2	-80.1	-167.7	175.5	-173.4	0	114.9	F182 L186	F182-K188 HydrophobicContact CD1-CD 4.46Å; F182-K188 PolarHBondContact O-N 3.47Å; F182-K188 VanDerWaalsContact O-N 3.13Å; L186-K188 HydrophobicContact CB-CG 4.06Å; L186-K188 PolarHBondContact O-N 2.99Å
189	F	84.8	Confident	87.5	Confident	57 Å²	57	64.4 Å²	64.4	25%	0.25	31%	0.31	C	S	.	.	S	Bend	trans	-109.3	136.6	-171.2	-59.9	-60.9	0	0	0	112.1	F178 F182 D183 E187 Q193 A194 I197	F178-F189 HydrophobicContact CE1-CE2 4.26Å; F178-F189 HydrophobicContact CE1-CZ 4.41Å; F178-F189 HydrophobicContact CZ-CE2 4.19Å; F178-F189 AromaticContact CZ-CZ 3.95Å; F178-F189 HydrophobicContact CZ-CZ 3.95Å; F182-F189 HydrophobicContact CB-CE2 3.71Å; F182-F189 HydrophobicContact CB-CZ 4.31Å; D183-F189 HydrophobicContact CB-CD2 4.34Å; E187-F189 VanDerWaalsContact C-N 3.25Å; E187-F189 PolarHBondContact O-N 2.79Å; F189-Q193 HydrophobicContact CB-CB 4.18Å; F189-A194 HydrophobicContact CB-CB 4.19Å; F189-I197 HydrophobicContact CB-CD1 4.45Å; F189-I197 HydrophobicContact CD1-CD1 3.58Å; F189-I197 HydrophobicContact CD2-CD1 3.73Å; F189-I197 HydrophobicContact CE1-CD1 3.6Å; F189-I197 HydrophobicContact CE2-CD1 3.74Å; F189-I197 HydrophobicContact CG-CD1 3.65Å; F189-I197 HydrophobicContact CZ-CD1 3.69Å
190	T	87.1	Confident	87.7	Confident	95 Å²	95	69.9 Å²	69.9	58%	0.583	34%	0.338	S	S	*	.			trans	-60.6	146.7	168.2	-52.2	0	0	0	0	109.9	K192 Q193 A194	T190-K192 PolarHBondContact O-N 3.46Å; T190-Q193 WeakPolarHBondContact O-CA 3.07Å; T190-Q193 WeakPolarHBondContact O-CB 3.41Å; T190-Q193 PolarHBondContact O-N 3.09Å; T190-A194 PolarHBondContact O-N 3.07Å
191	T	84.7	Confident	88	Confident	77 Å²	77	70.2 Å²	70.2	47%	0.472	34%	0.341	S	S	.	.	H	α-helix	trans	-44.6	-43.9	-177.7	-41.7	0	0	0	0	114	K127 F128 Q193 A194 Y195	K127-T191 WeakPolarHBondContact O-CG2 3.47Å; F128-T191 HydrophobicContact CD1-CG2 3.61Å; F128-T191 HydrophobicContact CE1-CG2 3.83Å; F128-T191 WeakPolarHBondContact CE1-O 3.3Å; T191-Q193 PolarHBondContact O-N 3.18Å; T191-A194 PolarHBondContact O-N 3.48Å; T191-Y195 PolarHBondContact O-N 3.36Å
192	K	86	Confident	88.1	Confident	180 Å²	180	67.2 Å²	67.2	78%	0.783	33%	0.325	S	S	*	.	H	α-helix	trans	-65.3	-35.5	177.4	-65.8	-174.5	179.3	-178.6	0	113.8	T190	T190-K192 PolarHBondContact O-N 3.46Å
193	Q	88.6	Confident	88.4	Confident	106 Å²	106	64.3 Å²	64.3	50%	0.495	32%	0.316	S	S	.	.	H	α-helix	trans	-74.6	-44.7	176.3	-68.3	173.1	-26.4	0	0	110.6	F189 T190 T191 Y195 V196 I197	F189-Q193 HydrophobicContact CB-CB 4.18Å; T190-Q193 WeakPolarHBondContact O-CA 3.07Å; T190-Q193 WeakPolarHBondContact O-CB 3.41Å; T190-Q193 PolarHBondContact O-N 3.09Å; T191-Q193 PolarHBondContact O-N 3.18Å; Q193-Y195 VanDerWaalsContact C-N 3.26Å; Q193-Y195 PolarHBondContact O-N 2.95Å; Q193-V196 PolarHBondContact O-N 3.37Å; Q193-I197 HydrophobicContact CB-CD1 4.46Å; Q193-I197 WeakPolarHBondContact O-CB 3.26Å; Q193-I197 VanDerWaalsContact O-CG1 3.26Å; Q193-I197 WeakPolarHBondContact O-CG1 3.49Å; Q193-I197 PolarHBondContact O-N 2.88Å
194	A	87.3	Confident	88.9	Confident	0 Å²	0	67.2 Å²	67.2	0%	0	33%	0.333	C	S	.	.	H	α-helix	trans	-54.9	-40.8	174.7	0	0	0	0	0	112.1	F128 D183 F189 T190 T191 N198	F128-A194 HydrophobicContact CE1-CB 4.15Å; F128-A194 HydrophobicContact CZ-CB 3.94Å; D183-A194 WeakPolarHBondContact OD1-CB 3.41Å; F189-A194 HydrophobicContact CB-CB 4.19Å; T190-A194 PolarHBondContact O-N 3.07Å; T191-A194 PolarHBondContact O-N 3.48Å; A194-N198 WeakPolarHBondContact O-CB 3.29Å; A194-N198 PolarHBondContact O-N 2.9Å; A194-N198 PolarHBondContact O-ND2 3.11Å
195	Y	89	Confident	89.4	Confident	46 Å²	46	67 Å²	67	18%	0.18	33%	0.332	C	S	.	.	H	α-helix	trans	-58.1	-54.7	176	-165	-83.5	0	0	0	112	F128 I133 D136 T191 Q193 I197 N198 L199	F128-Y195 AromaticContact CD1-CD2 3.82Å; F128-Y195 HydrophobicContact CD1-CD2 3.82Å; F128-Y195 HydrophobicContact CE1-CD2 4.06Å; F128-Y195 HydrophobicContact CG-CD2 4.37Å; I133-Y195 HydrophobicContact CB-CD2 4.37Å; I133-Y195 HydrophobicContact CB-CE2 3.7Å; I133-Y195 HydrophobicContact CD1-CD2 3.63Å; I133-Y195 HydrophobicContact CD1-CE2 3.8Å; I133-Y195 HydrophobicContact CD1-CG 4.31Å; I133-Y195 HydrophobicContact CG1-CD2 3.97Å; I133-Y195 HydrophobicContact CG1-CE2 3.58Å; D136-Y195 PolarHBondContact OD2-OH 3.48Å; T191-Y195 PolarHBondContact O-N 3.36Å; Q193-Y195 VanDerWaalsContact C-N 3.26Å; Q193-Y195 PolarHBondContact O-N 2.95Å; Y195-I197 PolarHBondContact O-N 3.3Å; Y195-N198 PolarHBondContact O-N 2.97Å; Y195-L199 WeakPolarHBondContact O-CB 3.31Å; Y195-L199 PolarHBondContact O-N 3.15Å
196	V	90.5	Very high	89.7	Confident	81 Å²	81	59.6 Å²	59.6	49%	0.491	30%	0.304	S	S	.	.	H	α-helix	trans	-65.4	-39.9	-178.4	176.7	0	0	0	0	111.3	Q193 L199 L200	Q193-V196 PolarHBondContact O-N 3.37Å; V196-L199 PolarHBondContact O-N 3.28Å; V196-L200 HydrophobicContact CG1-CD1 3.89Å; V196-L200 HydrophobicContact CG1-CG 4.33Å; V196-L200 WeakPolarHBondContact O-CB 3.34Å; V196-L200 VanDerWaalsContact O-CG 3.28Å; V196-L200 WeakPolarHBondContact O-CG 3.45Å; V196-L200 PolarHBondContact O-N 3.38Å
197	I	91.3	Very high	90.1	Very high	34 Å²	34	58.6 Å²	58.6	17%	0.174	30%	0.296	C	S	.	.	H	α-helix	trans	-62.8	-45.4	177.6	-75	168.9	0	0	0	111.3	F178 F189 Q193 Y195 S201	F178-I197 HydrophobicContact CD1-CG2 4.32Å; F178-I197 HydrophobicContact CE1-CG2 3.73Å; F189-I197 HydrophobicContact CB-CD1 4.45Å; F189-I197 HydrophobicContact CD1-CD1 3.58Å; F189-I197 HydrophobicContact CD2-CD1 3.73Å; F189-I197 HydrophobicContact CE1-CD1 3.6Å; F189-I197 HydrophobicContact CE2-CD1 3.74Å; F189-I197 HydrophobicContact CG-CD1 3.65Å; F189-I197 HydrophobicContact CZ-CD1 3.69Å; Q193-I197 HydrophobicContact CB-CD1 4.46Å; Q193-I197 WeakPolarHBondContact O-CB 3.26Å; Q193-I197 VanDerWaalsContact O-CG1 3.26Å; Q193-I197 WeakPolarHBondContact O-CG1 3.49Å; Q193-I197 PolarHBondContact O-N 2.88Å; Y195-I197 PolarHBondContact O-N 3.3Å; I197-S201 VanDerWaalsContact O-CB 3.27Å; I197-S201 WeakPolarHBondContact O-CB 3.42Å; I197-S201 PolarHBondContact O-N 2.9Å; I197-S201 PolarHBondContact O-OG 2.96Å
198	N	90.3	Very high	90.4	Very high	4 Å²	4	53.9 Å²	53.9	2%	0.021	27%	0.274	C	S	.	.	H	α-helix	trans	-64.6	-42.8	176.8	-81.3	-63.3	0	0	0	111.4	M137 V179 D183 A194 Y195 L200 S201 V202	M137-N198 HydrophobicContact CE-CB 3.77Å; V179-N198 WeakPolarHBondContact CG1-OD1 3.47Å; D183-N198 PolarHBondContact OD2-ND2 3.36Å; A194-N198 WeakPolarHBondContact O-CB 3.29Å; A194-N198 PolarHBondContact O-N 2.9Å; A194-N198 PolarHBondContact O-ND2 3.11Å; Y195-N198 PolarHBondContact O-N 2.97Å; N198-L200 PolarHBondContact O-N 3.32Å; N198-S201 WeakPolarHBondContact O-CB 3.27Å; N198-S201 PolarHBondContact O-N 2.88Å; N198-V202 WeakPolarHBondContact O-CG2 3.49Å; N198-V202 PolarHBondContact O-N 2.77Å
199	L	91.8	Very high	90.8	Very high	45 Å²	45	47.1 Å²	47.1	24%	0.236	25%	0.245	C	C	.	.	H	α-helix	trans	-62.9	-44.2	178.4	-158.9	68.7	0	0	0	112.3	D136 M137 T140 Y195 V196 V202 G203	D136-L199 HydrophobicContact CB-CD1 4.04Å; D136-L199 WeakPolarHBondContact O-CD1 3.46Å; M137-L199 HydrophobicContact CG-CD1 4.47Å; T140-L199 HydrophobicContact CG2-CD1 4.38Å; T140-L199 HydrophobicContact CG2-CG 4.31Å; T140-L199 WeakPolarHBondContact OG1-CD1 3.24Å; Y195-L199 WeakPolarHBondContact O-CB 3.31Å; Y195-L199 PolarHBondContact O-N 3.15Å; V196-L199 PolarHBondContact O-N 3.28Å; L199-V202 PolarHBondContact O-N 2.99Å; L199-G203 PolarHBondContact O-N 3.14Å
200	L	94.2	Very high	91.1	Very high	116 Å²	116	44.4 Å²	44.4	61%	0.607	23%	0.233	S	C	*	.	H	α-helix	trans	-63.1	-40.9	173.5	-72.5	171.5	0	0	0	111.7	V196 N198 G203 V204	V196-L200 HydrophobicContact CG1-CD1 3.89Å; V196-L200 HydrophobicContact CG1-CG 4.33Å; V196-L200 WeakPolarHBondContact O-CB 3.34Å; V196-L200 VanDerWaalsContact O-CG 3.28Å; V196-L200 WeakPolarHBondContact O-CG 3.45Å; V196-L200 PolarHBondContact O-N 3.38Å; N198-L200 PolarHBondContact O-N 3.32Å; L200-G203 PolarHBondContact O-N 3.39Å; L200-V204 WeakPolarHBondContact O-CG2 3.34Å; L200-V204 PolarHBondContact O-N 3.07Å
201	S	94.1	Very high	91.2	Very high	10 Å²	10	40.2 Å²	40.2	7%	0.07	21%	0.207	C	C	.	.	H	α-helix	trans	-62.1	-47.1	177.9	-62.8	0	0	0	0	111.4	V179 I197 N198 G203 V204 V205	V179-S201 WeakPolarHBondContact CG2-OG 3.49Å; I197-S201 VanDerWaalsContact O-CB 3.27Å; I197-S201 WeakPolarHBondContact O-CB 3.42Å; I197-S201 PolarHBondContact O-N 2.9Å; I197-S201 PolarHBondContact O-OG 2.96Å; N198-S201 WeakPolarHBondContact O-CB 3.27Å; N198-S201 PolarHBondContact O-N 2.88Å; S201-G203 VanDerWaalsContact C-N 3.31Å; S201-G203 PolarHBondContact O-N 3.41Å; S201-V204 PolarHBondContact O-N 3.22Å; S201-V205 VanDerWaalsContact O-CG2 3.27Å; S201-V205 WeakPolarHBondContact O-CG2 3.37Å; S201-V205 PolarHBondContact O-N 3.38Å
202	V	93.4	Very high	91.5	Very high	0 Å²	0	36.6 Å²	36.6	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-60.6	-39.5	174.2	170.9	0	0	0	0	111.3	Y114 F117 M137 N198 L199 V205 A206	Y114-V202 HydrophobicContact CD2-CG1 4.47Å; F117-V202 HydrophobicContact CB-CG2 3.76Å; F117-V202 HydrophobicContact CD1-CG2 3.77Å; F117-V202 HydrophobicContact CD2-CG2 4.04Å; F117-V202 HydrophobicContact CE1-CG2 4.4Å; F117-V202 HydrophobicContact CG-CG2 3.57Å; M137-V202 HydrophobicContact CB-CG1 4.34Å; M137-V202 HydrophobicContact CB-CG2 4.32Å; M137-V202 HydrophobicContact CG-CG2 4.05Å; M137-V202 WeakPolarHBondContact O-CG1 3.26Å; M137-V202 HydrophobicContact SD-CG2 3.94Å; N198-V202 WeakPolarHBondContact O-CG2 3.49Å; N198-V202 PolarHBondContact O-N 2.77Å; L199-V202 PolarHBondContact O-N 2.99Å; V202-V205 PolarHBondContact O-N 3.19Å; V202-A206 VanDerWaalsContact O-CB 3.29Å; V202-A206 WeakPolarHBondContact O-CB 3.46Å; V202-A206 PolarHBondContact O-N 2.93Å
203	G	94.7	Very high	91.7	Very high	11 Å²	11	28.2 Å²	28.2	11%	0.113	15%	0.148	C	C	.	.	H	α-helix	trans	-61.5	-45.7	173.8	0	0	0	0	0	113.4	V144 L199 L200 S201 A206 F207	V144-G203 VanDerWaalsContact CG1-O 3.28Å; V144-G203 WeakPolarHBondContact CG1-O 3.17Å; L199-G203 PolarHBondContact O-N 3.14Å; L200-G203 PolarHBondContact O-N 3.39Å; S201-G203 VanDerWaalsContact C-N 3.31Å; S201-G203 PolarHBondContact O-N 3.41Å; G203-A206 PolarHBondContact O-N 3.38Å; G203-F207 PolarHBondContact O-N 3.23Å
204	V	95.3	Very high	91.7	Very high	62 Å²	62	23.3 Å²	23.3	38%	0.376	13%	0.126	S	C	.	.	H	α-helix	trans	-63.9	-42.4	177	175	0	0	0	0	111.3	L171 P175 L200 S201 F207 G208	L171-V204 HydrophobicContact CB-CG1 4.17Å; L171-V204 HydrophobicContact CD2-CG1 3.92Å; P175-V204 HydrophobicContact CG-CB 4.04Å; P175-V204 HydrophobicContact CG-CG1 3.73Å; L200-V204 WeakPolarHBondContact O-CG2 3.34Å; L200-V204 PolarHBondContact O-N 3.07Å; S201-V204 PolarHBondContact O-N 3.22Å; V204-F207 PolarHBondContact O-N 3.38Å; V204-G208 PolarHBondContact O-N 3.05Å
205	V	94.4	Very high	91.8	Very high	0 Å²	0	23.3 Å²	23.3	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-62.4	-45.3	175.4	171	0	0	0	0	110.8	P113 F117 P175 S201 V202 F207 G208 C209	P113-V205 HydrophobicContact CB-CG1 3.64Å; F117-V205 HydrophobicContact CE2-CG2 3.92Å; F117-V205 HydrophobicContact CZ-CG2 4.43Å; P175-V205 HydrophobicContact CB-CG2 3.76Å; P175-V205 HydrophobicContact CG-CG2 3.91Å; S201-V205 VanDerWaalsContact O-CG2 3.27Å; S201-V205 WeakPolarHBondContact O-CG2 3.37Å; S201-V205 PolarHBondContact O-N 3.38Å; V202-V205 PolarHBondContact O-N 3.19Å; V205-F207 VanDerWaalsContact C-N 3.34Å; V205-F207 PolarHBondContact O-N 3.44Å; V205-G208 PolarHBondContact O-N 3.08Å; V205-C209 VanDerWaalsContact O-CB 3.3Å; V205-C209 WeakPolarHBondContact O-CB 3.3Å; V205-C209 PolarHBondContact O-N 3.2Å; V205-C209 PolarHBondContact O-SG 2.89Å
206	A	93.4	Very high	91.9	Very high	0 Å²	0	21.1 Å²	21.1	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-57	-46.4	176.8	0	0	0	0	0	112.1	Y141 V144 V202 G203 T210	Y141-A206 HydrophobicContact CD2-CB 3.35Å; Y141-A206 HydrophobicContact CE2-CB 3.77Å; Y141-A206 HydrophobicContact CG-CB 3.93Å; V144-A206 HydrophobicContact CB-CB 4.05Å; V144-A206 HydrophobicContact CG1-CB 4.15Å; V202-A206 VanDerWaalsContact O-CB 3.29Å; V202-A206 WeakPolarHBondContact O-CB 3.46Å; V202-A206 PolarHBondContact O-N 2.93Å; G203-A206 PolarHBondContact O-N 3.38Å; A206-T210 WeakPolarHBondContact O-CB 3.38Å; A206-T210 PolarHBondContact O-N 3.44Å; A206-T210 PolarHBondContact O-OG1 2.71Å
207	F	92.6	Very high	91.9	Very high	65 Å²	65	17.4 Å²	17.4	29%	0.285	10%	0.095	S	C	.	.	H	α-helix	trans	-62.6	-49.2	176.3	-175.9	-89.6	0	0	0	111.8	V144 A148 L151 L155 L171 G203 V204 V205 T210 V211	V144-F207 HydrophobicContact CG1-CB 3.9Å; A148-F207 HydrophobicContact CB-CD2 3.63Å; A148-F207 HydrophobicContact CB-CE2 4.09Å; A148-F207 HydrophobicContact CB-CG 4.32Å; L151-F207 HydrophobicContact CD2-CE2 3.81Å; L151-F207 HydrophobicContact CD2-CZ 3.96Å; L155-F207 HydrophobicContact CD1-CZ 4.3Å; L171-F207 HydrophobicContact CD1-CD1 3.89Å; L171-F207 HydrophobicContact CD1-CE1 4.26Å; G203-F207 PolarHBondContact O-N 3.23Å; V204-F207 PolarHBondContact O-N 3.38Å; V205-F207 VanDerWaalsContact C-N 3.34Å; V205-F207 PolarHBondContact O-N 3.44Å; F207-T210 PolarHBondContact O-N 3.25Å; F207-V211 HydrophobicContact CD1-CG2 4.44Å; F207-V211 HydrophobicContact CE1-CG2 4.08Å; F207-V211 HydrophobicContact CE2-CG2 4.48Å; F207-V211 HydrophobicContact CZ-CG2 4.1Å; F207-V211 WeakPolarHBondContact O-CG2 3.08Å; F207-V211 PolarHBondContact O-N 3.12Å; F207-V211 VanDerWaalsContact O-N 3.08Å
208	G	92.1	Very high	91.7	Very high	0 Å²	0	15.8 Å²	15.8	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-59.1	-55.7	179.9	0	0	0	0	0	112.8	G168 V204 V205 T210 V211 Q212	G168-G208 WeakPolarHBondContact CA-O 3.43Å; V204-G208 PolarHBondContact O-N 3.05Å; V205-G208 PolarHBondContact O-N 3.08Å; G208-T210 VanDerWaalsContact C-N 3.32Å; G208-T210 PolarHBondContact O-N 3.46Å; G208-V211 PolarHBondContact O-N 2.9Å; G208-Q212 VanDerWaalsContact O-CB 3.23Å; G208-Q212 WeakPolarHBondContact O-CB 3.48Å; G208-Q212 PolarHBondContact O-N 2.93Å
209	C	91.6	Very high	91.6	Very high	0 Å²	0	15.7 Å²	15.7	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-60.1	-39.6	179.1	-65.7	0	0	0	0	112	V205 Q212 Q213	V205-C209 VanDerWaalsContact O-CB 3.3Å; V205-C209 WeakPolarHBondContact O-CB 3.3Å; V205-C209 PolarHBondContact O-N 3.2Å; V205-C209 PolarHBondContact O-SG 2.89Å; C209-Q212 WeakPolarHBondContact O-CB 3.26Å; C209-Q212 PolarHBondContact O-N 3.11Å; C209-Q213 WeakPolarHBondContact O-CB 3.29Å; C209-Q213 PolarHBondContact O-N 3.28Å
210	T	90.4	Very high	91.4	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-66.5	-46.4	179.1	-60.4	0	0	0	0	112.4	A145 A148 V149 A206 F207 G208 Q212 S214	A145-T210 WeakPolarHBondContact CA-OG1 3.37Å; A145-T210 WeakPolarHBondContact CB-OG1 3.46Å; A148-T210 HydrophobicContact CB-CG2 3.78Å; V149-T210 HydrophobicContact CG2-CG2 3.56Å; A206-T210 WeakPolarHBondContact O-CB 3.38Å; A206-T210 PolarHBondContact O-N 3.44Å; A206-T210 PolarHBondContact O-OG1 2.71Å; F207-T210 PolarHBondContact O-N 3.25Å; G208-T210 VanDerWaalsContact C-N 3.32Å; G208-T210 PolarHBondContact O-N 3.46Å; T210-Q212 VanDerWaalsContact C-N 3.33Å; T210-S214 WeakPolarHBondContact O-CB 3.32Å; T210-S214 PolarHBondContact O-N 3.38Å; T210-S214 VanDerWaalsContact O-N 3.07Å
211	V	89.2	Confident	91.1	Very high	8 Å²	8	8.2 Å²	8.2	5%	0.048	5%	0.048	C	C	.	.	H	α-helix	trans	-65.8	-38.4	177.3	172.7	0	0	0	0	110.9	A148 L155 R164 F207 G208 S215	A148-V211 HydrophobicContact CB-CG2 4.5Å; L155-V211 HydrophobicContact CD1-CG1 4.48Å; L155-V211 HydrophobicContact CD1-CG2 3.98Å; R164-V211 HydrophobicContact CB-CG1 4.16Å; R164-V211 HydrophobicContact CG-CG1 4.49Å; F207-V211 HydrophobicContact CD1-CG2 4.44Å; F207-V211 HydrophobicContact CE1-CG2 4.08Å; F207-V211 HydrophobicContact CE2-CG2 4.48Å; F207-V211 HydrophobicContact CZ-CG2 4.1Å; F207-V211 WeakPolarHBondContact O-CG2 3.08Å; F207-V211 PolarHBondContact O-N 3.12Å; F207-V211 VanDerWaalsContact O-N 3.08Å; G208-V211 PolarHBondContact O-N 2.9Å; V211-S215 WeakPolarHBondContact O-CB 3.49Å; V211-S215 PolarHBondContact O-N 2.99Å; V211-S215 VanDerWaalsContact O-N 3.13Å; V211-S215 PolarHBondContact O-OG 3.08Å
212	Q	90.4	Very high	90.7	Very high	0 Å²	0	8.1 Å²	8.1	0%	0	5%	0.046	C	C	.	.	H	α-helix	trans	-60.5	-60.2	173.9	179.4	169.1	-36.9	0	0	111.6	F110 I165 G168 Y169 G208 C209 T210 S214 S215 F216	F110-Q212 HydrophobicContact CD1-CG 3.94Å; F110-Q212 HydrophobicContact CE1-CG 3.79Å; I165-Q212 HydrophobicContact CG2-CG 4.47Å; G168-Q212 PolarHBondContact O-OE1 2.94Å; Y169-Q212 VanDerWaalsContact CA-OE1 3.27Å; Y169-Q212 VanDerWaalsContact CZ-NE2 3.28Å; G208-Q212 VanDerWaalsContact O-CB 3.23Å; G208-Q212 WeakPolarHBondContact O-CB 3.48Å; G208-Q212 PolarHBondContact O-N 2.93Å; C209-Q212 WeakPolarHBondContact O-CB 3.26Å; C209-Q212 PolarHBondContact O-N 3.11Å; T210-Q212 VanDerWaalsContact C-N 3.33Å; Q212-S214 PolarHBondContact O-N 3.43Å; Q212-S215 PolarHBondContact O-N 3.07Å; Q212-F216 WeakPolarHBondContact O-CB 3.22Å; Q212-F216 PolarHBondContact O-N 2.65Å
213	Q	91.1	Very high	90.4	Very high	4 Å²	4	8.6 Å²	8.6	2%	0.019	5%	0.049	C	C	.	.	H	α-helix	trans	-57.1	-48.2	-175.9	-176.8	178	29.2	0	0	111.1	F110 C209 F216 Y217 E235	F110-Q213 HydrophobicContact CB-CB 4.43Å; F110-Q213 HydrophobicContact CB-CG 4.47Å; F110-Q213 HydrophobicContact CD2-CB 4.06Å; F110-Q213 HydrophobicContact CD2-CG 3.77Å; F110-Q213 HydrophobicContact CE2-CG 4.35Å; F110-Q213 HydrophobicContact CG-CB 4.15Å; F110-Q213 HydrophobicContact CG-CG 4.26Å; C209-Q213 WeakPolarHBondContact O-CB 3.29Å; C209-Q213 PolarHBondContact O-N 3.28Å; Q213-F216 PolarHBondContact O-N 2.98Å; Q213-Y217 HydrophobicContact CG-CD2 3.89Å; Q213-Y217 HydrophobicContact CG-CE2 3.64Å; Q213-Y217 VanDerWaalsContact O-CD2 3.26Å; Q213-Y217 WeakPolarHBondContact O-CD2 3.49Å; Q213-Y217 PolarHBondContact O-N 2.89Å; Q213-E235 PolarHBondContact NE2-OE1 3.16Å
214	S	89.4	Confident	90.1	Very high	3 Å²	3	10 Å²	10	2%	0.021	6%	0.056	C	C	.	.	H	α-helix	trans	-64.5	-45.3	179.1	-170.4	0	0	0	0	112.4	N152 T210 Q212 F216 Y217 G218 N510 T513	N152-S214 VanDerWaalsContact ND2-CB 3.33Å; N152-S214 WeakPolarHBondContact ND2-CB 3.33Å; N152-S214 PolarHBondContact ND2-OG 2.88Å; T210-S214 WeakPolarHBondContact O-CB 3.32Å; T210-S214 PolarHBondContact O-N 3.38Å; T210-S214 VanDerWaalsContact O-N 3.07Å; Q212-S214 PolarHBondContact O-N 3.43Å; S214-F216 PolarHBondContact O-N 2.76Å; S214-Y217 PolarHBondContact O-N 2.81Å; S214-G218 PolarHBondContact O-N 3.38Å; S214-N510 PolarHBondContact O-OD1 3.38Å; S214-T513 WeakPolarHBondContact OG-CB 3.31Å
215	S	89.6	Confident	89.8	Confident	0 Å²	0	11.4 Å²	11.4	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-61.6	-31.4	175.3	-60.1	0	0	0	0	112.5	R164 V211 Q212 Y219	R164-S215 VanDerWaalsContact CB-OG 3.28Å; R164-S215 WeakPolarHBondContact CB-OG 3.15Å; R164-S215 WeakPolarHBondContact CD-OG 3.49Å; R164-S215 PolarHBondContact NH1-OG 3.4Å; V211-S215 WeakPolarHBondContact O-CB 3.49Å; V211-S215 PolarHBondContact O-N 2.99Å; V211-S215 VanDerWaalsContact O-N 3.13Å; V211-S215 PolarHBondContact O-OG 3.08Å; Q212-S215 PolarHBondContact O-N 3.07Å; S215-Y219 WeakPolarHBondContact O-CB 3.21Å; S215-Y219 PolarHBondContact O-N 3.15Å
216	F	90	Very high	89.6	Confident	1 Å²	1	16.2 Å²	16.2	0%	0.004	8%	0.075	C	C	.	.	H	α-helix	trans	-75.4	-35	176.7	-147.7	-81.2	0	0	0	112.4	M103 A106 F110 I165 Q212 Q213 S214 Y219 M220 V231 H278	M103-F216 HydrophobicContact SD-CE1 3.67Å; M103-F216 HydrophobicContact SD-CZ 3.59Å; M103-F216 VanDerWaalsContact SD-CZ 3.59Å; A106-F216 HydrophobicContact CB-CE1 3.93Å; A106-F216 HydrophobicContact CB-CE2 3.76Å; A106-F216 HydrophobicContact CB-CZ 3.36Å; F110-F216 HydrophobicContact CE1-CB 4.36Å; F110-F216 HydrophobicContact CE1-CD2 4.17Å; F110-F216 HydrophobicContact CE1-CG 4.26Å; F110-F216 HydrophobicContact CE2-CB 4.08Å; F110-F216 HydrophobicContact CE2-CD1 4.23Å; F110-F216 HydrophobicContact CE2-CG 4.19Å; F110-F216 HydrophobicContact CZ-CB 3.56Å; F110-F216 AromaticContact CZ-CD1 3.72Å; F110-F216 HydrophobicContact CZ-CD1 3.72Å; F110-F216 AromaticContact CZ-CD2 3.72Å; F110-F216 HydrophobicContact CZ-CD2 3.72Å; F110-F216 HydrophobicContact CZ-CE1 4.28Å; F110-F216 HydrophobicContact CZ-CE2 4.27Å; F110-F216 AromaticContact CZ-CG 3.41Å; F110-F216 HydrophobicContact CZ-CG 3.41Å; F110-F216 VanDerWaalsContact CZ-CG 3.41Å; I165-F216 HydrophobicContact CD1-CD2 3.94Å; I165-F216 HydrophobicContact CG1-CD2 4.36Å; I165-F216 HydrophobicContact CG2-CD2 4.15Å; Q212-F216 WeakPolarHBondContact O-CB 3.22Å; Q212-F216 PolarHBondContact O-N 2.65Å; Q213-F216 PolarHBondContact O-N 2.98Å; S214-F216 PolarHBondContact O-N 2.76Å; F216-Y219 HydrophobicContact CD1-CD1 4.38Å; F216-Y219 HydrophobicContact CD2-CD1 4.41Å; F216-Y219 HydrophobicContact CE1-CD1 4.32Å; F216-Y219 HydrophobicContact CE2-CD1 4.37Å; F216-Y219 HydrophobicContact CG-CD1 4.43Å; F216-Y219 HydrophobicContact CZ-CD1 4.32Å; F216-Y219 HydrophobicContact CZ-CE1 4.36Å; F216-Y219 WeakPolarHBondContact O-CB 3.31Å; F216-Y219 PolarHBondContact O-N 2.81Å; F216-M220 HydrophobicContact CD1-CE 3.86Å; F216-M220 HydrophobicContact CD1-CG 3.93Å; F216-M220 HydrophobicContact CD1-SD 4.3Å; F216-M220 HydrophobicContact CE1-CE 3.5Å; F216-M220 HydrophobicContact CE1-CG 4.18Å; F216-M220 HydrophobicContact CE1-SD 3.94Å; F216-M220 HydrophobicContact CZ-CE 4.26Å; F216-M220 WeakPolarHBondContact O-CG 3.44Å; F216-M220 PolarHBondContact O-N 2.69Å; F216-V231 HydrophobicContact CD1-CG2 3.94Å; F216-V231 HydrophobicContact CE1-CG2 3.62Å; F216-H278 AromaticContact CE2-ND1 3.6Å
217	Y	90.6	Very high	89.4	Confident	3 Å²	3	16.2 Å²	16.2	1%	0.012	8%	0.075	C	C	.	.	H	α-helix	trans	-69.1	-36	170.9	-81.5	-65.6	0	0	0	112.6	Q213 S214 M220 G221 T228 V231 M232 E235 M493 T513	Q213-Y217 HydrophobicContact CG-CD2 3.89Å; Q213-Y217 HydrophobicContact CG-CE2 3.64Å; Q213-Y217 VanDerWaalsContact O-CD2 3.26Å; Q213-Y217 WeakPolarHBondContact O-CD2 3.49Å; Q213-Y217 PolarHBondContact O-N 2.89Å; S214-Y217 PolarHBondContact O-N 2.81Å; Y217-M220 PolarHBondContact O-N 3.07Å; Y217-G221 PolarHBondContact O-N 2.5Å; Y217-T228 HydrophobicContact CD1-CG2 4.32Å; Y217-T228 HydrophobicContact CE1-CG2 4.31Å; Y217-V231 HydrophobicContact CE1-CG1 4.16Å; Y217-M232 HydrophobicContact CE1-CG 3.81Å; Y217-M232 HydrophobicContact CE1-SD 4.33Å; Y217-M232 VanDerWaalsContact OH-CG 3.32Å; Y217-M232 WeakPolarHBondContact OH-CG 2.99Å; Y217-E235 WeakPolarHBondContact CE2-OE1 3.5Å; Y217-E235 PolarHBondContact OH-OE1 3.43Å; Y217-E235 PolarHBondContact OH-OE2 3.37Å; Y217-M493 HydrophobicContact CD1-CE 4.04Å; Y217-M493 HydrophobicContact CD1-CG 3.75Å; Y217-M493 HydrophobicContact CD1-SD 3.71Å; Y217-M493 HydrophobicContact CD2-CE 4.36Å; Y217-M493 HydrophobicContact CE1-CE 4.25Å; Y217-M493 HydrophobicContact CE1-CG 3.77Å; Y217-M493 HydrophobicContact CE1-SD 4.23Å; Y217-M493 HydrophobicContact CG-CE 4.12Å; Y217-M493 HydrophobicContact CG-SD 4.12Å; Y217-T513 VanDerWaalsContact CB-OG1 3.32Å; Y217-T513 WeakPolarHBondContact CB-OG1 3.41Å; Y217-T513 HydrophobicContact CD2-CG2 4.36Å
218	G	88.1	Confident	89.4	Confident	0 Å²	0	13.4 Å²	13.4	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-57.4	-48.7	166.9	0	0	0	0	0	111.7	S214 M220 G221 E506	S214-G218 PolarHBondContact O-N 3.38Å; G218-M220 PolarHBondContact O-N 2.85Å; G218-G221 PolarHBondContact O-N 3.46Å; G218-E506 VanDerWaalsContact CA-O 3.27Å; G218-E506 WeakPolarHBondContact CA-O 3.43Å; G218-E506 WeakPolarHBondContact O-CA 3.38Å
219	Y	86.5	Confident	89.5	Confident	1 Å²	1	13.8 Å²	13.8	0%	0.004	7%	0.065	C	C	.	.	H	α-helix	trans	-58.1	-44.5	174.9	177.3	-137.4	0	0	0	113.1	M103 M161 I165 S215 F216 G221 M222 V287 T291	M103-Y219 HydrophobicContact CE-CE1 3.91Å; M103-Y219 HydrophobicContact SD-CE1 4.39Å; M161-Y219 HydrophobicContact CE-CD2 3.34Å; M161-Y219 HydrophobicContact CE-CE2 3.97Å; M161-Y219 HydrophobicContact CE-CG 3.71Å; M161-Y219 WeakPolarHBondContact SD-CB 3.46Å; M161-Y219 HydrophobicContact SD-CD2 3.7Å; M161-Y219 HydrophobicContact SD-CG 3.82Å; I165-Y219 HydrophobicContact CD1-CD1 4.43Å; S215-Y219 WeakPolarHBondContact O-CB 3.21Å; S215-Y219 PolarHBondContact O-N 3.15Å; F216-Y219 HydrophobicContact CD1-CD1 4.38Å; F216-Y219 HydrophobicContact CD2-CD1 4.41Å; F216-Y219 HydrophobicContact CE1-CD1 4.32Å; F216-Y219 HydrophobicContact CE2-CD1 4.37Å; F216-Y219 HydrophobicContact CG-CD1 4.43Å; F216-Y219 HydrophobicContact CZ-CD1 4.32Å; F216-Y219 HydrophobicContact CZ-CE1 4.36Å; F216-Y219 WeakPolarHBondContact O-CB 3.31Å; F216-Y219 PolarHBondContact O-N 2.81Å; Y219-G221 VanDerWaalsContact C-N 3.31Å; Y219-G221 PolarHBondContact O-N 2.76Å; Y219-M222 WeakPolarHBondContact O-CB 3.38Å; Y219-M222 PolarHBondContact O-N 2.64Å; Y219-V287 HydrophobicContact CE2-CG1 3.99Å; Y219-V287 WeakPolarHBondContact OH-CG1 3.23Å; Y219-V287 WeakPolarHBondContact OH-CG2 3.46Å; Y219-T291 HydrophobicContact CD2-CG2 4.18Å; Y219-T291 HydrophobicContact CE2-CG2 3.79Å
220	M	89	Confident	89.5	Confident	0 Å²	0	13.8 Å²	13.8	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-65.3	-32.3	177.5	-71.4	-50.8	90.4	0	0	112.9	M103 F216 Y217 G218 M222 L223 T228 V231	M103-M220 HydrophobicContact CB-SD 4.49Å; M103-M220 HydrophobicContact CE-CE 3.74Å; M103-M220 HydrophobicContact CE-SD 4.4Å; M103-M220 HydrophobicContact CG-CE 4.41Å; M103-M220 HydrophobicContact CG-SD 3.99Å; M103-M220 HydrophobicContact SD-CE 3.58Å; M103-M220 VanDerWaalsContact SD-CE 3.58Å; M103-M220 HydrophobicContact SD-SD 3.91Å; F216-M220 HydrophobicContact CD1-CE 3.86Å; F216-M220 HydrophobicContact CD1-CG 3.93Å; F216-M220 HydrophobicContact CD1-SD 4.3Å; F216-M220 HydrophobicContact CE1-CE 3.5Å; F216-M220 HydrophobicContact CE1-CG 4.18Å; F216-M220 HydrophobicContact CE1-SD 3.94Å; F216-M220 HydrophobicContact CZ-CE 4.26Å; F216-M220 WeakPolarHBondContact O-CG 3.44Å; F216-M220 PolarHBondContact O-N 2.69Å; Y217-M220 PolarHBondContact O-N 3.07Å; G218-M220 PolarHBondContact O-N 2.85Å; M220-M222 PolarHBondContact O-N 3.43Å; M220-M222 VanDerWaalsContact O-N 3.12Å; M220-L223 HydrophobicContact CE-CD1 3.55Å; M220-L223 HydrophobicContact CE-CG 4.43Å; M220-L223 PolarHBondContact O-N 2.97Å; M220-L223 HydrophobicContact SD-CD1 4.04Å; M220-T228 HydrophobicContact CB-CG2 4.45Å; M220-V231 HydrophobicContact CG-CB 4.47Å; M220-V231 HydrophobicContact CG-CG2 3.63Å; M220-V231 HydrophobicContact SD-CG2 3.65Å
221	G	86.2	Confident	89.7	Confident	5 Å²	5	13.8 Å²	13.8	5%	0.052	7%	0.065	C	C	.	.	H	α-helix	trans	-56.2	-28.2	174.2	0	0	0	0	0	113.2	Y217 G218 Y219 R505	Y217-G221 PolarHBondContact O-N 2.5Å; G218-G221 PolarHBondContact O-N 3.46Å; Y219-G221 VanDerWaalsContact C-N 3.31Å; Y219-G221 PolarHBondContact O-N 2.76Å; G221-R505 WeakPolarHBondContact O-CB 3.5Å; G221-R505 VanDerWaalsContact O-CD 3.27Å; G221-R505 WeakPolarHBondContact O-CD 3.43Å
222	M	86.1	Confident	89.9	Confident	7 Å²	7	13.6 Å²	13.6	3%	0.034	6%	0.064	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.6	-16.4	178.3	-52.9	172.4	79.7	0	0	113.3	M161 Y219 M220 T291 A294 Q295 E506	M161-M222 HydrophobicContact SD-SD 4.46Å; Y219-M222 WeakPolarHBondContact O-CB 3.38Å; Y219-M222 PolarHBondContact O-N 2.64Å; M220-M222 PolarHBondContact O-N 3.43Å; M220-M222 VanDerWaalsContact O-N 3.12Å; M222-T291 HydrophobicContact CE-CG2 4.28Å; M222-T291 HydrophobicContact SD-CG2 4.33Å; M222-A294 HydrophobicContact CB-CB 4.22Å; M222-A294 HydrophobicContact CE-CB 3.67Å; M222-A294 HydrophobicContact CG-CB 4.34Å; M222-Q295 HydrophobicContact CE-CG 3.89Å; M222-E506 HydrophobicContact CG-CB 4.47Å; M222-E506 HydrophobicContact SD-CB 4.32Å
223	L	87.9	Confident	90.1	Very high	11 Å²	11	13.8 Å²	13.8	6%	0.058	7%	0.065	C	C	.	.	S	Bend	trans	-97.6	165.9	-177.8	-60.7	-174	0	0	0	111.7	M103 M220 Y227 F286 Y290	M103-L223 HydrophobicContact CE-CD1 3.64Å; M220-L223 HydrophobicContact CE-CD1 3.55Å; M220-L223 HydrophobicContact CE-CG 4.43Å; M220-L223 PolarHBondContact O-N 2.97Å; M220-L223 HydrophobicContact SD-CD1 4.04Å; L223-Y227 HydrophobicContact CB-CD2 3.98Å; L223-Y227 HydrophobicContact CB-CG 4.31Å; L223-Y227 HydrophobicContact CD1-CD2 4.43Å; L223-Y227 HydrophobicContact CD1-CG 4.18Å; L223-F286 HydrophobicContact CD2-CE1 4.44Å; L223-Y290 HydrophobicContact CD2-CD2 4.37Å; L223-Y290 HydrophobicContact CD2-CG 4.1Å
224	P	88.6	Confident	90.2	Very high	40 Å²	40	13.6 Å²	13.6	26%	0.26	6%	0.064	S	C	.	.			trans	-55.7	144.2	171.7	-27.7	35.6	0	0	0	113.3	R226 Y227 Y290	P224-R226 HydrophobicContact CB-CG 4.44Å; P224-R226 PolarHBondContact O-N 3.33Å; P224-Y227 HydrophobicContact CB-CD2 4.14Å; P224-Y227 HydrophobicContact CB-CE2 4.26Å; P224-Y227 HydrophobicContact CG-CD2 4.32Å; P224-Y227 HydrophobicContact CG-CE2 4.17Å; P224-Y227 WeakPolarHBondContact O-CD2 3.3Å; P224-Y227 PolarHBondContact O-N 3.03Å; P224-Y290 HydrophobicContact CG-CD1 4.5Å; P224-Y290 HydrophobicContact CG-CE1 3.81Å; P224-Y290 HydrophobicContact CG-CE2 4.29Å
225	K	88.5	Confident	90.3	Very high	92 Å²	92	13.6 Å²	13.6	40%	0.4	6%	0.064	S	C	.	.	H	α-helix	trans	-41.3	-36	-177	-71.5	-176.9	-177.2	172.5	0	114.6	Y227 T228 Q229 D436 I494	K225-Y227 VanDerWaalsContact C-N 3.27Å; K225-Y227 PolarHBondContact O-N 3.37Å; K225-T228 PolarHBondContact O-N 3.17Å; K225-Q229 PolarHBondContact O-N 2.92Å; K225-D436 IonicContact NZ-OD1 2.74Å; K225-D436 PolarHBondContact NZ-OD1 2.87Å; K225-D436 IonicContact NZ-OD2 3.93Å; K225-I494 HydrophobicContact CB-CG2 3.76Å; K225-I494 HydrophobicContact CD-CG2 4.3Å; K225-I494 HydrophobicContact CG-CG2 4.1Å
226	R	89.4	Confident	90.5	Very high	100 Å²	100	13.8 Å²	13.8	38%	0.377	7%	0.065	S	C	.	.	H	α-helix	trans	-56.6	-33.2	178.7	73.5	-177.8	-176.3	-167.7	-0.1	114.2	Y100 P224 Q229 G230	Y100-R226 WeakPolarHBondContact CE2-O 3.42Å; P224-R226 HydrophobicContact CB-CG 4.44Å; P224-R226 PolarHBondContact O-N 3.33Å; R226-Q229 PolarHBondContact O-N 3.42Å; R226-G230 PolarHBondContact O-N 3.44Å
227	Y	91.1	Very high	90.6	Very high	0 Å²	0	15.1 Å²	15.1	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-76.1	-39.1	-177.2	-66.5	-74.7	0	0	0	112.4	D94 I99 M103 L223 P224 K225 Q229 G230 V231 F286	D94-Y227 VanDerWaalsContact CB-OH 3.25Å; D94-Y227 WeakPolarHBondContact CB-OH 3.24Å; D94-Y227 VanDerWaalsContact CG-OH 3.31Å; D94-Y227 WeakPolarHBondContact OD2-CE1 3.17Å; D94-Y227 PolarHBondContact OD2-OH 2.97Å; I99-Y227 HydrophobicContact CB-CE1 4.06Å; I99-Y227 HydrophobicContact CG2-CD1 4.24Å; I99-Y227 HydrophobicContact CG2-CE1 3.76Å; M103-Y227 HydrophobicContact CB-CD1 4.46Å; M103-Y227 HydrophobicContact CG-CD1 3.74Å; M103-Y227 HydrophobicContact CG-CG 4.44Å; L223-Y227 HydrophobicContact CB-CD2 3.98Å; L223-Y227 HydrophobicContact CB-CG 4.31Å; L223-Y227 HydrophobicContact CD1-CD2 4.43Å; L223-Y227 HydrophobicContact CD1-CG 4.18Å; P224-Y227 HydrophobicContact CB-CD2 4.14Å; P224-Y227 HydrophobicContact CB-CE2 4.26Å; P224-Y227 HydrophobicContact CG-CD2 4.32Å; P224-Y227 HydrophobicContact CG-CE2 4.17Å; P224-Y227 WeakPolarHBondContact O-CD2 3.3Å; P224-Y227 PolarHBondContact O-N 3.03Å; K225-Y227 VanDerWaalsContact C-N 3.27Å; K225-Y227 PolarHBondContact O-N 3.37Å; Y227-Q229 VanDerWaalsContact C-N 3.3Å; Y227-Q229 PolarHBondContact O-N 2.77Å; Y227-G230 PolarHBondContact O-N 3.16Å; Y227-V231 WeakPolarHBondContact O-CG2 3.49Å; Y227-V231 PolarHBondContact O-N 3.43Å; Y227-F286 AromaticContact CE2-CE1 3.78Å; Y227-F286 HydrophobicContact CE2-CE1 3.78Å; Y227-F286 AromaticContact CE2-CZ 3.53Å; Y227-F286 HydrophobicContact CE2-CZ 3.53Å; Y227-F286 AromaticContact CZ-CE1 3.85Å; Y227-F286 AromaticContact CZ-CZ 3.66Å; Y227-F286 WeakPolarHBondContact OH-CZ 3.29Å
228	T	91.9	Very high	90.7	Very high	6 Å²	6	15 Å²	15	4%	0.037	7%	0.073	C	C	.	.	H	α-helix	trans	-57.3	-45.7	169.8	-45.9	0	0	0	0	110.7	Y217 M220 K225 G230 V231 M232 M493 I494	Y217-T228 HydrophobicContact CD1-CG2 4.32Å; Y217-T228 HydrophobicContact CE1-CG2 4.31Å; M220-T228 HydrophobicContact CB-CG2 4.45Å; K225-T228 PolarHBondContact O-N 3.17Å; T228-G230 VanDerWaalsContact C-N 3.34Å; T228-G230 PolarHBondContact O-N 2.96Å; T228-V231 PolarHBondContact O-N 3.11Å; T228-M232 VanDerWaalsContact O-CG 3.32Å; T228-M232 WeakPolarHBondContact O-CG 3.43Å; T228-M232 PolarHBondContact O-N 3.28Å; T228-M493 HydrophobicContact CG2-CG 3.82Å; T228-I494 HydrophobicContact CG2-CG1 4.16Å
229	Q	93.2	Very high	90.7	Very high	9 Å²	9	15.5 Å²	15.5	4%	0.042	8%	0.078	C	C	.	.	H	α-helix	trans	-61.9	-39.6	176.9	-174.1	-80.8	-23.4	0	0	112.4	Y100 K225 R226 Y227 M232 T233 K428 A432 I494	Y100-Q229 PolarHBondContact OH-OE1 3.22Å; Y100-Q229 VanDerWaalsContact OH-OE1 3.07Å; K225-Q229 PolarHBondContact O-N 2.92Å; R226-Q229 PolarHBondContact O-N 3.42Å; Y227-Q229 VanDerWaalsContact C-N 3.3Å; Y227-Q229 PolarHBondContact O-N 2.77Å; Q229-M232 PolarHBondContact O-N 2.63Å; Q229-T233 PolarHBondContact NE2-OG1 2.74Å; Q229-T233 WeakPolarHBondContact O-CB 2.95Å; Q229-T233 PolarHBondContact O-N 3.48Å; Q229-T233 PolarHBondContact O-OG1 2.81Å; Q229-K428 PolarHBondContact NE2-O 3.17Å; Q229-A432 HydrophobicContact CG-CB 4.01Å; Q229-I494 HydrophobicContact CB-CD1 3.61Å; Q229-I494 HydrophobicContact CB-CG1 4.05Å; Q229-I494 HydrophobicContact CG-CD1 3.82Å
230	G	92.8	Very high	91	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-59.7	-49.8	174.4	0	0	0	0	0	112.6	L104 R226 Y227 T228 M232 T233 G234	L104-G230 WeakPolarHBondContact CA-O 3.12Å; R226-G230 PolarHBondContact O-N 3.44Å; Y227-G230 PolarHBondContact O-N 3.16Å; T228-G230 VanDerWaalsContact C-N 3.34Å; T228-G230 PolarHBondContact O-N 2.96Å; G230-M232 VanDerWaalsContact C-N 3.35Å; G230-M232 PolarHBondContact O-N 3.48Å; G230-T233 PolarHBondContact O-N 3.12Å; G230-G234 PolarHBondContact O-N 2.68Å
231	V	94.1	Very high	90.9	Very high	0 Å²	0	19.4 Å²	19.4	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-55.9	-49.1	175.1	175.7	0	0	0	0	111.2	M103 G107 F110 F216 Y217 M220 Y227 T228 T233 G234 E235	M103-V231 HydrophobicContact CB-CG2 3.87Å; M103-V231 WeakPolarHBondContact O-CG2 3.15Å; G107-V231 WeakPolarHBondContact CA-O 3.35Å; F110-V231 HydrophobicContact CD2-CG1 4.33Å; F110-V231 HydrophobicContact CE2-CG1 3.59Å; F110-V231 HydrophobicContact CZ-CG1 4.44Å; F216-V231 HydrophobicContact CD1-CG2 3.94Å; F216-V231 HydrophobicContact CE1-CG2 3.62Å; Y217-V231 HydrophobicContact CE1-CG1 4.16Å; M220-V231 HydrophobicContact CG-CB 4.47Å; M220-V231 HydrophobicContact CG-CG2 3.63Å; M220-V231 HydrophobicContact SD-CG2 3.65Å; Y227-V231 WeakPolarHBondContact O-CG2 3.49Å; Y227-V231 PolarHBondContact O-N 3.43Å; T228-V231 PolarHBondContact O-N 3.11Å; V231-T233 VanDerWaalsContact C-N 3.32Å; V231-T233 PolarHBondContact O-N 2.72Å; V231-G234 WeakPolarHBondContact O-CA 3.31Å; V231-G234 PolarHBondContact O-N 3.01Å; V231-E235 PolarHBondContact O-N 3.49Å; V231-E235 VanDerWaalsContact O-N 3.12Å
232	M	92.9	Very high	90.8	Very high	3 Å²	3	20 Å²	20	2%	0.015	10%	0.101	C	C	.	.	H	α-helix	trans	-63.1	-40.4	-178.4	-66.3	-163.6	80.2	0	0	111.7	Y217 T228 Q229 G230 G234 E235 S236 K428 S490 M493	Y217-M232 HydrophobicContact CE1-CG 3.81Å; Y217-M232 HydrophobicContact CE1-SD 4.33Å; Y217-M232 VanDerWaalsContact OH-CG 3.32Å; Y217-M232 WeakPolarHBondContact OH-CG 2.99Å; T228-M232 VanDerWaalsContact O-CG 3.32Å; T228-M232 WeakPolarHBondContact O-CG 3.43Å; T228-M232 PolarHBondContact O-N 3.28Å; Q229-M232 PolarHBondContact O-N 2.63Å; G230-M232 VanDerWaalsContact C-N 3.35Å; G230-M232 PolarHBondContact O-N 3.48Å; M232-G234 VanDerWaalsContact C-N 3.28Å; M232-G234 PolarHBondContact O-N 3.1Å; M232-E235 WeakPolarHBondContact O-CB 3.24Å; M232-E235 PolarHBondContact O-N 2.73Å; M232-S236 PolarHBondContact O-N 2.91Å; M232-K428 VanDerWaalsContact C-CD 3.42Å; M232-K428 HydrophobicContact CB-CD 4Å; M232-K428 WeakPolarHBondContact O-CD 3.46Å; M232-K428 PolarHBondContact O-NZ 3.13Å; M232-S490 VanDerWaalsContact SD-CA 3.55Å; M232-M493 HydrophobicContact CE-CB 4.11Å; M232-M493 HydrophobicContact CE-CG 4.38Å; M232-M493 HydrophobicContact SD-CB 3.51Å; M232-M493 VanDerWaalsContact SD-CB 3.51Å; M232-M493 HydrophobicContact SD-CG 3.64Å
233	T	94.3	Very high	90.9	Very high	4 Å²	4	20.4 Å²	20.4	3%	0.025	10%	0.104	C	C	.	.	H	α-helix	trans	-61.6	-37.7	173.7	-57.7	0	0	0	0	111.6	L104 Q229 G230 V231 E235 S236 T237 F425 I429	L104-T233 HydrophobicContact CD1-CG2 4.26Å; Q229-T233 PolarHBondContact NE2-OG1 2.74Å; Q229-T233 WeakPolarHBondContact O-CB 2.95Å; Q229-T233 PolarHBondContact O-N 3.48Å; Q229-T233 PolarHBondContact O-OG1 2.81Å; G230-T233 PolarHBondContact O-N 3.12Å; V231-T233 VanDerWaalsContact C-N 3.32Å; V231-T233 PolarHBondContact O-N 2.72Å; T233-E235 VanDerWaalsContact C-N 3.35Å; T233-E235 PolarHBondContact O-N 3.07Å; T233-S236 PolarHBondContact O-N 3.27Å; T233-T237 WeakPolarHBondContact O-CB 3.3Å; T233-T237 PolarHBondContact O-N 2.87Å; T233-T237 PolarHBondContact O-OG1 3.3Å; T233-F425 HydrophobicContact CG2-CD2 4.01Å; T233-F425 HydrophobicContact CG2-CE2 3.63Å; T233-I429 HydrophobicContact CG2-CG1 4.08Å
234	G	93.8	Very high	90.7	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-56.1	-45	171.9	0	0	0	0	0	113.4	L104 V108 G230 V231 M232 S236 T237 A238	L104-G234 WeakPolarHBondContact O-CA 3.07Å; V108-G234 WeakPolarHBondContact CA-O 3.33Å; V108-G234 WeakPolarHBondContact CG2-O 3.33Å; G230-G234 PolarHBondContact O-N 2.68Å; V231-G234 WeakPolarHBondContact O-CA 3.31Å; V231-G234 PolarHBondContact O-N 3.01Å; M232-G234 VanDerWaalsContact C-N 3.28Å; M232-G234 PolarHBondContact O-N 3.1Å; G234-S236 VanDerWaalsContact C-N 3.32Å; G234-S236 PolarHBondContact O-N 3.48Å; G234-T237 VanDerWaalsContact O-CB 3.31Å; G234-T237 WeakPolarHBondContact O-CB 3.48Å; G234-T237 PolarHBondContact O-N 2.98Å; G234-T237 VanDerWaalsContact O-N 3.12Å; G234-A238 PolarHBondContact O-N 2.94Å
235	E	92.3	Very high	90.3	Very high	4 Å²	4	22.6 Å²	22.6	2%	0.019	12%	0.115	C	C	.	.	H	α-helix	trans	-58.1	-42.4	178.1	-70.5	176.8	169.5	0	0	112.5	G107 L111 Q213 Y217 V231 M232 T233 A238 G239 K428	G107-E235 WeakPolarHBondContact O-CA 3.39Å; L111-E235 HydrophobicContact CD1-CB 3.54Å; L111-E235 HydrophobicContact CD1-CG 3.94Å; L111-E235 WeakPolarHBondContact CD1-O 3.45Å; Q213-E235 PolarHBondContact NE2-OE1 3.16Å; Y217-E235 WeakPolarHBondContact CE2-OE1 3.5Å; Y217-E235 PolarHBondContact OH-OE1 3.43Å; Y217-E235 PolarHBondContact OH-OE2 3.37Å; V231-E235 PolarHBondContact O-N 3.49Å; V231-E235 VanDerWaalsContact O-N 3.12Å; M232-E235 WeakPolarHBondContact O-CB 3.24Å; M232-E235 PolarHBondContact O-N 2.73Å; T233-E235 VanDerWaalsContact C-N 3.35Å; T233-E235 PolarHBondContact O-N 3.07Å; E235-A238 WeakPolarHBondContact O-CB 3.36Å; E235-A238 PolarHBondContact O-N 3.36Å; E235-G239 PolarHBondContact O-N 2.9Å; E235-K428 IonicContact OE2-NZ 3.94Å; E235-K428 PolarHBondContact OE2-NZ 2.97Å
236	S	93.1	Very high	89.8	Confident	3 Å²	3	22.1 Å²	22.1	2%	0.021	11%	0.111	C	C	.	.	H	α-helix	trans	-77.5	-27.5	177.2	-52.4	0	0	0	0	112.6	M232 T233 G234 A238 G239 V240 D424 K428	M232-S236 PolarHBondContact O-N 2.91Å; T233-S236 PolarHBondContact O-N 3.27Å; G234-S236 VanDerWaalsContact C-N 3.32Å; G234-S236 PolarHBondContact O-N 3.48Å; S236-A238 VanDerWaalsContact C-N 3.25Å; S236-A238 PolarHBondContact O-N 3.23Å; S236-G239 PolarHBondContact O-N 3.13Å; S236-G239 VanDerWaalsContact O-N 3.11Å; S236-V240 WeakPolarHBondContact O-CG2 3.23Å; S236-V240 PolarHBondContact O-N 3.13Å; S236-D424 WeakPolarHBondContact CB-OD2 3.35Å; S236-D424 PolarHBondContact OG-OD2 2.95Å; S236-K428 WeakPolarHBondContact OG-CD 3.38Å; S236-K428 WeakPolarHBondContact OG-CE 3.28Å; S236-K428 PolarHBondContact OG-NZ 3.07Å
237	T	92.9	Very high	89.5	Confident	30 Å²	30	19.1 Å²	19.1	18%	0.184	10%	0.102	C	C	.	.	H	α-helix	trans	-59.8	-39.5	170.5	-52.9	0	0	0	0	110	V108 T233 G234 V240 I241 F425	V108-T237 HydrophobicContact CG2-CG2 4.13Å; T233-T237 WeakPolarHBondContact O-CB 3.3Å; T233-T237 PolarHBondContact O-N 2.87Å; T233-T237 PolarHBondContact O-OG1 3.3Å; G234-T237 VanDerWaalsContact O-CB 3.31Å; G234-T237 WeakPolarHBondContact O-CB 3.48Å; G234-T237 PolarHBondContact O-N 2.98Å; G234-T237 VanDerWaalsContact O-N 3.12Å; T237-V240 PolarHBondContact O-N 3.48Å; T237-I241 HydrophobicContact CG2-CD1 4.05Å; T237-I241 VanDerWaalsContact O-CG1 3.26Å; T237-I241 WeakPolarHBondContact O-CG1 3.3Å; T237-I241 PolarHBondContact O-N 2.97Å; T237-F425 VanDerWaalsContact OG1-CE2 3.22Å; T237-F425 WeakPolarHBondContact OG1-CE2 3.4Å
238	A	91.2	Very high	89	Confident	0 Å²	0	24.7 Å²	24.7	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-58.6	-50.4	170.5	0	0	0	0	0	111.4	V108 L111 L112 G234 E235 S236 V240 I241 I242	V108-A238 HydrophobicContact CG1-CB 4.06Å; L111-A238 HydrophobicContact CB-CB 3.94Å; L112-A238 HydrophobicContact CD2-CB 4.26Å; L112-A238 HydrophobicContact CG-CB 4.34Å; G234-A238 PolarHBondContact O-N 2.94Å; E235-A238 WeakPolarHBondContact O-CB 3.36Å; E235-A238 PolarHBondContact O-N 3.36Å; S236-A238 VanDerWaalsContact C-N 3.25Å; S236-A238 PolarHBondContact O-N 3.23Å; A238-V240 VanDerWaalsContact C-N 3.28Å; A238-V240 PolarHBondContact O-N 3.49Å; A238-I241 WeakPolarHBondContact O-CB 3.42Å; A238-I241 PolarHBondContact O-N 3.33Å; A238-I242 HydrophobicContact CB-CD1 4.39Å; A238-I242 WeakPolarHBondContact O-CD1 3.12Å; A238-I242 VanDerWaalsContact O-CG1 3.23Å; A238-I242 WeakPolarHBondContact O-CG1 3.01Å; A238-I242 PolarHBondContact O-N 2.9Å
239	G	89.4	Confident	88.2	Confident	11 Å²	11	25.4 Å²	25.4	11%	0.113	13%	0.131	C	C	.	.	H	α-helix	trans	-55.4	-39.5	178	0	0	0	0	0	113.8	E235 S236 S243	E235-G239 PolarHBondContact O-N 2.9Å; S236-G239 PolarHBondContact O-N 3.13Å; S236-G239 VanDerWaalsContact O-N 3.11Å; G239-S243 WeakPolarHBondContact O-CB 3.45Å; G239-S243 PolarHBondContact O-N 3.01Å; G239-S243 PolarHBondContact O-OG 3.29Å
240	V	91.4	Very high	87.3	Confident	19 Å²	19	29.2 Å²	29.2	12%	0.115	15%	0.147	C	C	.	.	H	α-helix	trans	-66.9	-47.1	173.1	173.6	0	0	0	0	111.4	S236 T237 A238 I242 S243 L244 N421 M422 F425	S236-V240 WeakPolarHBondContact O-CG2 3.23Å; S236-V240 PolarHBondContact O-N 3.13Å; T237-V240 PolarHBondContact O-N 3.48Å; A238-V240 VanDerWaalsContact C-N 3.28Å; A238-V240 PolarHBondContact O-N 3.49Å; V240-I242 VanDerWaalsContact C-N 3.31Å; V240-I242 PolarHBondContact O-N 3.28Å; V240-S243 PolarHBondContact O-N 3.4Å; V240-L244 HydrophobicContact CG1-CD1 3.78Å; V240-L244 HydrophobicContact CG1-CG 4.24Å; V240-L244 WeakPolarHBondContact O-CB 3.28Å; V240-L244 WeakPolarHBondContact O-CG 3.32Å; V240-L244 PolarHBondContact O-N 2.74Å; V240-N421 HydrophobicContact CG2-CB 4.46Å; V240-N421 WeakPolarHBondContact CG2-O 3.41Å; V240-M422 HydrophobicContact CG1-CE 3.75Å; V240-M422 HydrophobicContact CG1-SD 4.39Å; V240-M422 HydrophobicContact CG2-CE 4.47Å; V240-M422 HydrophobicContact CG2-SD 4.31Å; V240-F425 HydrophobicContact CG2-CB 3.89Å; V240-F425 HydrophobicContact CG2-CG 4.3Å
241	I	88.3	Confident	86.6	Confident	63 Å²	63	34.4 Å²	34.4	32%	0.323	17%	0.174	S	C	.	.	H	α-helix	trans	-56.2	-45.4	176.5	-71.4	164	0	0	0	110.9	V108 T237 A238 S245	V108-I241 HydrophobicContact CG1-CD1 4.33Å; T237-I241 HydrophobicContact CG2-CD1 4.05Å; T237-I241 VanDerWaalsContact O-CG1 3.26Å; T237-I241 WeakPolarHBondContact O-CG1 3.3Å; T237-I241 PolarHBondContact O-N 2.97Å; A238-I241 WeakPolarHBondContact O-CB 3.42Å; A238-I241 PolarHBondContact O-N 3.33Å; I241-S245 WeakPolarHBondContact O-CB 3.32Å; I241-S245 PolarHBondContact O-N 2.85Å
242	I	84.6	Confident	85.8	Confident	18 Å²	18	40.2 Å²	40.2	9%	0.092	21%	0.205	C	C	.	.	H	α-helix	trans	-66.4	-43.8	179.7	-63.4	151.1	0	0	0	111.1	L112 N115 T119 A238 V240 S245 R246 F263	L112-I242 HydrophobicContact CD2-CD1 4.35Å; L112-I242 HydrophobicContact CD2-CG1 4.17Å; N115-I242 HydrophobicContact CB-CD1 3.27Å; N115-I242 HydrophobicContact CB-CG1 3.88Å; N115-I242 WeakPolarHBondContact ND2-CD1 3.42Å; T119-I242 HydrophobicContact CG2-CG2 4.37Å; T119-I242 WeakPolarHBondContact OG1-CG2 3.47Å; A238-I242 HydrophobicContact CB-CD1 4.39Å; A238-I242 WeakPolarHBondContact O-CD1 3.12Å; A238-I242 VanDerWaalsContact O-CG1 3.23Å; A238-I242 WeakPolarHBondContact O-CG1 3.01Å; A238-I242 PolarHBondContact O-N 2.9Å; V240-I242 VanDerWaalsContact C-N 3.31Å; V240-I242 PolarHBondContact O-N 3.28Å; I242-S245 PolarHBondContact O-N 2.62Å; I242-R246 WeakPolarHBondContact O-CB 3.42Å; I242-R246 PolarHBondContact O-N 2.97Å; I242-F263 HydrophobicContact CG1-CZ 4.44Å
243	S	86.8	Confident	84.9	Confident	16 Å²	16	43 Å²	43	11%	0.112	22%	0.219	C	C	.	.	H	α-helix	trans	-63.6	-45.5	178.7	-58.7	0	0	0	0	111.8	G239 V240 R246 I247 N421	G239-S243 WeakPolarHBondContact O-CB 3.45Å; G239-S243 PolarHBondContact O-N 3.01Å; G239-S243 PolarHBondContact O-OG 3.29Å; V240-S243 PolarHBondContact O-N 3.4Å; S243-R246 PolarHBondContact O-N 2.99Å; S243-I247 WeakPolarHBondContact O-CG1 3.31Å; S243-I247 PolarHBondContact O-N 3.07Å; S243-I247 VanDerWaalsContact O-N 3.16Å; S243-N421 PolarHBondContact OG-ND2 3.27Å
244	L	85	Confident	83.8	Confident	74 Å²	74	49.2 Å²	49.2	39%	0.387	26%	0.26	S	S	.	.	H	α-helix	trans	-65.5	-42.7	175.9	-69.9	175.9	0	0	0	111.2	V240 R246 I247 F248	V240-L244 HydrophobicContact CG1-CD1 3.78Å; V240-L244 HydrophobicContact CG1-CG 4.24Å; V240-L244 WeakPolarHBondContact O-CB 3.28Å; V240-L244 WeakPolarHBondContact O-CG 3.32Å; V240-L244 PolarHBondContact O-N 2.74Å; L244-R246 PolarHBondContact O-N 2.72Å; L244-I247 PolarHBondContact O-N 2.85Å; L244-F248 HydrophobicContact CB-CD2 4.36Å; L244-F248 HydrophobicContact CB-CE2 4.18Å; L244-F248 WeakPolarHBondContact O-CD2 3.36Å; L244-F248 PolarHBondContact O-N 3.27Å
245	S	80.3	Confident	83.2	Confident	23 Å²	23	52 Å²	52	16%	0.161	28%	0.275	C	S	.	.	H	α-helix	trans	-54.4	-55.4	173.8	-177.5	0	0	0	0	110	I241 I242 I247 F248 T249 F263	I241-S245 WeakPolarHBondContact O-CB 3.32Å; I241-S245 PolarHBondContact O-N 2.85Å; I242-S245 PolarHBondContact O-N 2.62Å; S245-I247 PolarHBondContact O-N 2.9Å; S245-I247 VanDerWaalsContact O-N 3.13Å; S245-F248 CarbonylContact O-C 3.59Å; S245-F248 WeakPolarHBondContact O-CA 3.42Å; S245-F248 PolarHBondContact O-N 3.42Å; S245-T249 VanDerWaalsContact O-CG2 3.28Å; S245-T249 WeakPolarHBondContact O-CG2 3.41Å; S245-T249 PolarHBondContact O-N 2.97Å; S245-T249 PolarHBondContact O-OG1 3.22Å; S245-F263 WeakPolarHBondContact OG-CD2 3.46Å; S245-F263 VanDerWaalsContact OG-CE2 3.31Å; S245-F263 WeakPolarHBondContact OG-CE2 3.48Å
246	R	77.6	Confident	82.4	Confident	82 Å²	82	55.7 Å²	55.7	31%	0.309	29%	0.292	S	S	.	.	H	α-helix	trans	-57.2	-31.3	179.7	-166.6	176	-172.6	-168.6	3.2	114.2	I242 S243 L244 T249 K250	I242-R246 WeakPolarHBondContact O-CB 3.42Å; I242-R246 PolarHBondContact O-N 2.97Å; S243-R246 PolarHBondContact O-N 2.99Å; L244-R246 PolarHBondContact O-N 2.72Å; R246-T249 WeakPolarHBondContact CA-OG1 3.46Å; R246-T249 PolarHBondContact O-OG1 3.33Å; R246-K250 WeakPolarHBondContact O-CB 3.33Å; R246-K250 PolarHBondContact O-N 2.97Å
247	I	82.9	Confident	81.8	Confident	36 Å²	36	58.9 Å²	58.9	19%	0.185	31%	0.305	C	S	.	.	H	α-helix	trans	-72	-47.8	172.9	-68	164.6	0	0	0	110.4	S243 L244 S245 L251 I414 A418	S243-I247 WeakPolarHBondContact O-CG1 3.31Å; S243-I247 PolarHBondContact O-N 3.07Å; S243-I247 VanDerWaalsContact O-N 3.16Å; L244-I247 PolarHBondContact O-N 2.85Å; S245-I247 PolarHBondContact O-N 2.9Å; S245-I247 VanDerWaalsContact O-N 3.13Å; I247-L251 HydrophobicContact CG2-CD1 3.85Å; I247-L251 WeakPolarHBondContact O-CB 3.49Å; I247-L251 WeakPolarHBondContact O-CD1 3.44Å; I247-L251 VanDerWaalsContact O-CG 3.24Å; I247-L251 WeakPolarHBondContact O-CG 3.31Å; I247-L251 PolarHBondContact O-N 3.05Å; I247-I414 HydrophobicContact CD1-CG2 4.49Å; I247-I414 HydrophobicContact CG1-CG2 3.82Å; I247-A418 HydrophobicContact CD1-CB 4.04Å
248	F	80.4	Confident	81.3	Confident	118 Å²	118	63.5 Å²	63.5	52%	0.518	32%	0.323	S	S	.	.	H	α-helix	trans	-66	-40.8	179.3	-71.6	-56.7	0	0	0	113	L244 S245 L251 L252	L244-F248 HydrophobicContact CB-CD2 4.36Å; L244-F248 HydrophobicContact CB-CE2 4.18Å; L244-F248 WeakPolarHBondContact O-CD2 3.36Å; L244-F248 PolarHBondContact O-N 3.27Å; S245-F248 CarbonylContact O-C 3.59Å; S245-F248 WeakPolarHBondContact O-CA 3.42Å; S245-F248 PolarHBondContact O-N 3.42Å; F248-L251 PolarHBondContact O-N 3.35Å; F248-L251 VanDerWaalsContact O-N 3.15Å; F248-L252 HydrophobicContact CD1-CD1 4.27Å; F248-L252 WeakPolarHBondContact O-CB 3.37Å; F248-L252 PolarHBondContact O-N 2.99Å
249	T	74.6	Confident	80.7	Confident	21 Å²	21	64.3 Å²	64.3	13%	0.129	33%	0.327	C	S	.	.	H	α-helix	trans	-62.1	-48	179.7	60.2	0	0	0	0	110.9	S245 R246 L251 I253 N259	S245-T249 VanDerWaalsContact O-CG2 3.28Å; S245-T249 WeakPolarHBondContact O-CG2 3.41Å; S245-T249 PolarHBondContact O-N 2.97Å; S245-T249 PolarHBondContact O-OG1 3.22Å; R246-T249 WeakPolarHBondContact CA-OG1 3.46Å; R246-T249 PolarHBondContact O-OG1 3.33Å; T249-L251 PolarHBondContact O-N 2.89Å; T249-L251 VanDerWaalsContact O-N 3.16Å; T249-I253 PolarHBondContact O-N 2.84Å; T249-N259 VanDerWaalsContact CB-OD1 3.28Å; T249-N259 WeakPolarHBondContact CB-OD1 3.37Å; T249-N259 WeakPolarHBondContact CG2-OD1 3.32Å
250	K	74.1	Confident	80.3	Confident	89 Å²	89	63.9 Å²	63.9	39%	0.387	32%	0.322	S	S	.	.	H	α-helix	trans	-63.7	-16.7	176	-169.5	162.9	-175.1	163.4	0	113.8	R246 E410 W411 I414	R246-K250 WeakPolarHBondContact O-CB 3.33Å; R246-K250 PolarHBondContact O-N 2.97Å; K250-E410 IonicContact NZ-OE2 2.89Å; K250-E410 PolarHBondContact NZ-OE2 3.28Å; K250-W411 HydrophobicContact CD-CH2 4.31Å; K250-W411 HydrophobicContact CD-CZ2 4.4Å; K250-W411 HydrophobicContact CG-CH2 4.19Å; K250-W411 HydrophobicContact CG-CZ2 4.39Å; K250-I414 HydrophobicContact CD-CD1 4.03Å
251	L	79.4	Confident	79.9	Confident	108 Å²	108	65 Å²	65	57%	0.565	33%	0.327	S	S	*	.	H	α-helix	trans	-102.6	-34	179.7	-70.9	173.6	0	0	0	114.6	I247 F248 T249 W411	I247-L251 HydrophobicContact CG2-CD1 3.85Å; I247-L251 WeakPolarHBondContact O-CB 3.49Å; I247-L251 WeakPolarHBondContact O-CD1 3.44Å; I247-L251 VanDerWaalsContact O-CG 3.24Å; I247-L251 WeakPolarHBondContact O-CG 3.31Å; I247-L251 PolarHBondContact O-N 3.05Å; F248-L251 PolarHBondContact O-N 3.35Å; F248-L251 VanDerWaalsContact O-N 3.15Å; T249-L251 PolarHBondContact O-N 2.89Å; T249-L251 VanDerWaalsContact O-N 3.16Å; L251-W411 HydrophobicContact CD2-CH2 3.75Å; L251-W411 HydrophobicContact CD2-CZ2 4.23Å; L251-W411 HydrophobicContact CG-CH2 4.05Å
252	L	77.2	Confident	79.7	Confident	122 Å²	122	65.9 Å²	65.9	64%	0.639	33%	0.332	S	S	*	.	H	α-helix	trans	-107.4	-28.3	-168.2	-84.2	67.7	0	0	0	114.5	F248	F248-L252 HydrophobicContact CD1-CD1 4.27Å; F248-L252 WeakPolarHBondContact O-CB 3.37Å; F248-L252 PolarHBondContact O-N 2.99Å
253	I	74.1	Confident	79.5	Confident	63 Å²	63	65.4 Å²	65.4	32%	0.323	33%	0.329	S	S	.	.			trans	-125.5	104.1	-166	-52	-179.5	0	0	0	111	T249 D255 N259 I262	T249-I253 PolarHBondContact O-N 2.84Å; I253-D255 VanDerWaalsContact C-N 3.29Å; I253-D255 HydrophobicContact CG2-CB 4.46Å; I253-D255 WeakPolarHBondContact CG2-O 3.29Å; I253-D255 PolarHBondContact O-N 3.27Å; I253-N259 HydrophobicContact CB-CB 4.28Å; I253-N259 HydrophobicContact CG2-CB 3.86Å; I253-I262 HydrophobicContact CD1-CD1 4.42Å
254	P	71.6	Confident	79.4	Confident	134 Å²	134	65 Å²	65	87%	0.87	33%	0.325	S	S	*	.			trans	-79.7	-7.5	176.6	32.4	-35.7	0	0	0	114
255	D	80.3	Confident	79.6	Confident	59 Å²	59	65.8 Å²	65.8	32%	0.316	33%	0.33	S	S	.	.			trans	-98	96.7	177	-175	-34.9	0	0	0	110	I253 K257 K258 N259	I253-D255 VanDerWaalsContact C-N 3.29Å; I253-D255 HydrophobicContact CG2-CB 4.46Å; I253-D255 WeakPolarHBondContact CG2-O 3.29Å; I253-D255 PolarHBondContact O-N 3.27Å; D255-K257 VanDerWaalsContact C-N 3.28Å; D255-K257 PolarHBondContact O-N 2.93Å; D255-K257 PolarHBondContact OD1-N 3.43Å; D255-K258 HydrophobicContact CB-CB 4.22Å; D255-K258 HydrophobicContact CB-CG 4.41Å; D255-K258 PolarHBondContact O-N 3.4Å; D255-K258 PolarHBondContact OD1-N 2.95Å; D255-K258 WeakPolarHBondContact OD2-CG 3.38Å; D255-K258 IonicContact OD2-NZ 2.6Å; D255-K258 PolarHBondContact OD2-NZ 3.06Å; D255-N259 WeakPolarHBondContact O-CB 3.41Å; D255-N259 PolarHBondContact O-N 3.43Å
256	E	76.4	Confident	79.9	Confident	80 Å²	80	69.2 Å²	69.2	37%	0.374	35%	0.345	S	S	.	.	H	α-helix	trans	-52.4	-43.3	-178.7	-63.4	173.2	-173.3	0	0	112.4	D122 H126 N259 T260	D122-E256 HydrophobicContact CB-CG 4.49Å; H126-E256 WeakPolarHBondContact CB-OE2 3.16Å; H126-E256 IonicContact CG-OE2 3.6Å; E256-N259 WeakPolarHBondContact O-CB 3.39Å; E256-N259 PolarHBondContact O-N 3.31Å; E256-T260 WeakPolarHBondContact O-CB 3.23Å; E256-T260 PolarHBondContact O-N 3.38Å; E256-T260 PolarHBondContact O-OG1 3.47Å
257	K	79.7	Confident	80.4	Confident	70 Å²	70	65.3 Å²	65.3	30%	0.304	33%	0.33	S	S	.	.	H	α-helix	trans	-68.9	-43.7	-175.8	-178.7	175.9	178.9	171.7	0	111.9	Y123 V184 E187 D255 N259 L261	Y123-K257 HydrophobicContact CE2-CB 4.47Å; Y123-K257 HydrophobicContact CE2-CG 4.44Å; V184-K257 WeakPolarHBondContact O-CE 3.36Å; E187-K257 VanDerWaalsContact OE1-CE 3.29Å; E187-K257 WeakPolarHBondContact OE1-CE 3.17Å; E187-K257 IonicContact OE1-NZ 3.88Å; E187-K257 PolarHBondContact OE1-NZ 3.12Å; E187-K257 IonicContact OE2-NZ 2.76Å; E187-K257 PolarHBondContact OE2-NZ 3.19Å; D255-K257 VanDerWaalsContact C-N 3.28Å; D255-K257 PolarHBondContact O-N 2.93Å; D255-K257 PolarHBondContact OD1-N 3.43Å; K257-N259 VanDerWaalsContact C-N 3.32Å; K257-L261 PolarHBondContact O-N 3.29Å; K257-L261 VanDerWaalsContact O-N 3.08Å
258	K	81.5	Confident	80.8	Confident	127 Å²	127	64.8 Å²	64.8	55%	0.552	33%	0.328	S	S	*	.	H	α-helix	trans	-65.2	-39.2	175.2	-71.1	-169.1	-172.3	87.3	0	111.2	D255 L261 I262	D255-K258 HydrophobicContact CB-CB 4.22Å; D255-K258 HydrophobicContact CB-CG 4.41Å; D255-K258 PolarHBondContact O-N 3.4Å; D255-K258 PolarHBondContact OD1-N 2.95Å; D255-K258 WeakPolarHBondContact OD2-CG 3.38Å; D255-K258 IonicContact OD2-NZ 2.6Å; D255-K258 PolarHBondContact OD2-NZ 3.06Å; K258-L261 PolarHBondContact O-N 3.34Å; K258-I262 WeakPolarHBondContact O-CD1 3.47Å; K258-I262 VanDerWaalsContact O-CG1 3.29Å; K258-I262 WeakPolarHBondContact O-CG1 3.26Å; K258-I262 PolarHBondContact O-N 3.25Å
259	N	79.3	Confident	81.3	Confident	17 Å²	17	62.8 Å²	62.8	9%	0.091	33%	0.328	C	S	.	.	H	α-helix	trans	-58	-54.5	175.9	-179.3	62	0	0	0	112	T249 I253 D255 E256 K257 L261 I262 F263	T249-N259 VanDerWaalsContact CB-OD1 3.28Å; T249-N259 WeakPolarHBondContact CB-OD1 3.37Å; T249-N259 WeakPolarHBondContact CG2-OD1 3.32Å; I253-N259 HydrophobicContact CB-CB 4.28Å; I253-N259 HydrophobicContact CG2-CB 3.86Å; D255-N259 WeakPolarHBondContact O-CB 3.41Å; D255-N259 PolarHBondContact O-N 3.43Å; E256-N259 WeakPolarHBondContact O-CB 3.39Å; E256-N259 PolarHBondContact O-N 3.31Å; K257-N259 VanDerWaalsContact C-N 3.32Å; N259-L261 VanDerWaalsContact C-N 3.33Å; N259-L261 PolarHBondContact O-N 3.19Å; N259-I262 PolarHBondContact O-N 3.15Å; N259-I262 VanDerWaalsContact O-N 3.14Å; N259-F263 PolarHBondContact O-N 2.69Å
260	T	80.9	Confident	82	Confident	2 Å²	2	63.7 Å²	63.7	1%	0.012	33%	0.332	C	S	.	.	H	α-helix	trans	-55.8	-45.6	177.1	-62.6	0	0	0	0	112	D120 Y123 V184 E256 I262 F263 F264	D120-T260 HydrophobicContact CB-CG2 3.92Å; D120-T260 WeakPolarHBondContact CB-OG1 3.36Å; D120-T260 WeakPolarHBondContact OD1-CA 3.41Å; D120-T260 VanDerWaalsContact OD1-CB 3.3Å; D120-T260 WeakPolarHBondContact OD1-CB 3.37Å; D120-T260 PolarHBondContact OD1-OG1 3Å; Y123-T260 WeakPolarHBondContact CB-OG1 3.3Å; Y123-T260 HydrophobicContact CD1-CG2 4.15Å; Y123-T260 HydrophobicContact CG-CG2 4.36Å; V184-T260 HydrophobicContact CG1-CG2 3.93Å; V184-T260 HydrophobicContact CG2-CG2 4.24Å; E256-T260 WeakPolarHBondContact O-CB 3.23Å; E256-T260 PolarHBondContact O-N 3.38Å; E256-T260 PolarHBondContact O-OG1 3.47Å; T260-I262 VanDerWaalsContact C-N 3.34Å; T260-I262 PolarHBondContact O-N 3.35Å; T260-F263 PolarHBondContact O-N 2.98Å; T260-F264 HydrophobicContact CG2-CD2 3.77Å; T260-F264 HydrophobicContact CG2-CE2 3.78Å; T260-F264 WeakPolarHBondContact O-CD2 3.42Å; T260-F264 PolarHBondContact O-N 3.45Å
261	L	83.1	Confident	82.8	Confident	42 Å²	42	59.5 Å²	59.5	22%	0.22	31%	0.313	C	S	.	.	H	α-helix	trans	-61.3	-41	178.1	-173.5	63.6	0	0	0	112.5	W185 K257 K258 N259 L265	W185-L261 HydrophobicContact CB-CD1 4.22Å; K257-L261 PolarHBondContact O-N 3.29Å; K257-L261 VanDerWaalsContact O-N 3.08Å; K258-L261 PolarHBondContact O-N 3.34Å; N259-L261 VanDerWaalsContact C-N 3.33Å; N259-L261 PolarHBondContact O-N 3.19Å; L261-L265 HydrophobicContact CG-CD1 4.27Å; L261-L265 WeakPolarHBondContact O-CB 3.21Å; L261-L265 VanDerWaalsContact O-CG 3.26Å; L261-L265 WeakPolarHBondContact O-CG 3.19Å; L261-L265 PolarHBondContact O-N 3.36Å
262	I	83.5	Confident	83.4	Confident	82 Å²	82	57.9 Å²	57.9	42%	0.421	30%	0.304	S	S	.	.	H	α-helix	trans	-63.8	-42.5	175.9	-68.9	163.9	0	0	0	110.7	I253 K258 N259 T260 L265 I266	I253-I262 HydrophobicContact CD1-CD1 4.42Å; K258-I262 WeakPolarHBondContact O-CD1 3.47Å; K258-I262 VanDerWaalsContact O-CG1 3.29Å; K258-I262 WeakPolarHBondContact O-CG1 3.26Å; K258-I262 PolarHBondContact O-N 3.25Å; N259-I262 PolarHBondContact O-N 3.15Å; N259-I262 VanDerWaalsContact O-N 3.14Å; T260-I262 VanDerWaalsContact C-N 3.34Å; T260-I262 PolarHBondContact O-N 3.35Å; I262-L265 PolarHBondContact O-N 2.8Å; I262-I266 HydrophobicContact CG2-CD1 3.84Å; I262-I266 HydrophobicContact CG2-CG1 4.47Å; I262-I266 WeakPolarHBondContact O-CG1 3.39Å; I262-I266 PolarHBondContact O-N 3.3Å
263	F	80.7	Confident	84.2	Confident	8 Å²	8	55.9 Å²	55.9	4%	0.035	29%	0.293	C	S	.	.	H	α-helix	trans	-64.6	-47	179.8	-166.7	-118.5	0	0	0	112.2	T119 I242 S245 N259 T260 L265 I266 S267	T119-F263 HydrophobicContact CG2-CD1 4.29Å; T119-F263 HydrophobicContact CG2-CE1 3.78Å; T119-F263 HydrophobicContact CG2-CZ 3.95Å; T119-F263 WeakPolarHBondContact OG1-CE1 3.43Å; I242-F263 HydrophobicContact CG1-CZ 4.44Å; S245-F263 WeakPolarHBondContact OG-CD2 3.46Å; S245-F263 VanDerWaalsContact OG-CE2 3.31Å; S245-F263 WeakPolarHBondContact OG-CE2 3.48Å; N259-F263 PolarHBondContact O-N 2.69Å; T260-F263 PolarHBondContact O-N 2.98Å; F263-L265 VanDerWaalsContact C-N 3.31Å; F263-L265 PolarHBondContact O-N 2.72Å; F263-I266 PolarHBondContact O-N 3.05Å; F263-S267 PolarHBondContact O-N 3.34Å; F263-S267 PolarHBondContact O-OG 3.49Å
264	F	86.1	Confident	85.1	Confident	8 Å²	8	53 Å²	53	4%	0.035	28%	0.279	C	S	.	.	H	α-helix	trans	-57.4	-41.3	172.8	-88	-81.3	0	0	0	112.3	S116 F117 L176 V179 V184 T260 S267 I268	S116-F264 WeakPolarHBondContact O-CZ 3.21Å; F117-F264 HydrophobicContact CD1-CE1 4.5Å; F117-F264 HydrophobicContact CD1-CZ 4.27Å; F117-F264 HydrophobicContact CE1-CE1 4.29Å; F117-F264 HydrophobicContact CE1-CZ 4.41Å; F117-F264 HydrophobicContact CZ-CE1 4.4Å; L176-F264 HydrophobicContact CD2-CD1 4.06Å; L176-F264 HydrophobicContact CD2-CE1 3.93Å; V179-F264 HydrophobicContact CG1-CZ 4.31Å; V184-F264 HydrophobicContact CG2-CE2 4.4Å; T260-F264 HydrophobicContact CG2-CD2 3.77Å; T260-F264 HydrophobicContact CG2-CE2 3.78Å; T260-F264 WeakPolarHBondContact O-CD2 3.42Å; T260-F264 PolarHBondContact O-N 3.45Å; F264-S267 PolarHBondContact O-N 3.32Å; F264-I268 WeakPolarHBondContact O-CB 3.46Å; F264-I268 WeakPolarHBondContact O-CD1 3.38Å; F264-I268 WeakPolarHBondContact O-CG1 3.44Å; F264-I268 PolarHBondContact O-N 2.88Å
265	L	88.3	Confident	86	Confident	91 Å²	91	48.4 Å²	48.4	48%	0.476	25%	0.245	S	C	.	.	H	α-helix	trans	-65.3	-40	177.6	-75	170.6	0	0	0	112.9	L261 I262 F263 S269	L261-L265 HydrophobicContact CG-CD1 4.27Å; L261-L265 WeakPolarHBondContact O-CB 3.21Å; L261-L265 VanDerWaalsContact O-CG 3.26Å; L261-L265 WeakPolarHBondContact O-CG 3.19Å; L261-L265 PolarHBondContact O-N 3.36Å; I262-L265 PolarHBondContact O-N 2.8Å; F263-L265 VanDerWaalsContact C-N 3.31Å; F263-L265 PolarHBondContact O-N 2.72Å; L265-S269 VanDerWaalsContact O-CB 3.3Å; L265-S269 WeakPolarHBondContact O-CB 3.48Å; L265-S269 PolarHBondContact O-N 2.91Å; L265-S269 PolarHBondContact O-OG 3.04Å
266	I	86.2	Confident	86.6	Confident	94 Å²	94	50 Å²	50	48%	0.482	25%	0.253	S	S	.	.	H	α-helix	trans	-62.5	-48.7	175	-70.4	166.9	0	0	0	109.9	I262 F263 S269 M270	I262-I266 HydrophobicContact CG2-CD1 3.84Å; I262-I266 HydrophobicContact CG2-CG1 4.47Å; I262-I266 WeakPolarHBondContact O-CG1 3.39Å; I262-I266 PolarHBondContact O-N 3.3Å; F263-I266 PolarHBondContact O-N 3.05Å; I266-S269 PolarHBondContact O-N 3.28Å; I266-M270 WeakPolarHBondContact O-CB 3.39Å; I266-M270 PolarHBondContact O-N 3.47Å
267	S	87.7	Confident	87.2	Confident	1 Å²	1	48.8 Å²	48.8	1%	0.007	25%	0.249	C	C	.	.	H	α-helix	trans	-64.3	-42.7	179.6	-66.9	0	0	0	0	113.1	S116 F263 F264 S269 M270 E271	S116-S267 WeakPolarHBondContact OG-CB 3.32Å; S116-S267 PolarHBondContact OG-OG 3.17Å; F263-S267 PolarHBondContact O-N 3.34Å; F263-S267 PolarHBondContact O-OG 3.49Å; F264-S267 PolarHBondContact O-N 3.32Å; S267-S269 VanDerWaalsContact C-N 3.34Å; S267-S269 PolarHBondContact O-N 3.21Å; S267-M270 PolarHBondContact O-N 2.84Å; S267-E271 WeakPolarHBondContact O-CB 3.39Å; S267-E271 PolarHBondContact O-N 3.26Å
268	I	91.6	Very high	87.6	Confident	24 Å²	24	45.8 Å²	45.8	12%	0.123	24%	0.236	C	C	.	.	H	α-helix	trans	-61.4	-44	174.3	-70.3	162.5	0	0	0	110.4	L176 I177 F264 E271 M272	L176-I268 HydrophobicContact CB-CD1 4.42Å; L176-I268 HydrophobicContact CB-CG1 3.93Å; I177-I268 HydrophobicContact CD1-CG2 4.34Å; I177-I268 HydrophobicContact CG1-CD1 3.98Å; I177-I268 HydrophobicContact CG1-CG1 4.16Å; I177-I268 HydrophobicContact CG1-CG2 3.95Å; F264-I268 WeakPolarHBondContact O-CB 3.46Å; F264-I268 WeakPolarHBondContact O-CD1 3.38Å; F264-I268 WeakPolarHBondContact O-CG1 3.44Å; F264-I268 PolarHBondContact O-N 2.88Å; I268-E271 PolarHBondContact O-N 3.23Å; I268-M272 HydrophobicContact CG2-CG 4.38Å; I268-M272 VanDerWaalsContact O-CB 3.31Å; I268-M272 WeakPolarHBondContact O-CB 3Å; I268-M272 VanDerWaalsContact O-CG 3.22Å; I268-M272 WeakPolarHBondContact O-CG 3.19Å; I268-M272 PolarHBondContact O-N 3.01Å
269	S	91.3	Very high	87.9	Confident	76 Å²	76	41.6 Å²	41.6	53%	0.531	22%	0.22	S	C	.	.	H	α-helix	trans	-64.3	-42	179.6	-58.9	0	0	0	0	112	L265 I266 S267 L273	L265-S269 VanDerWaalsContact O-CB 3.3Å; L265-S269 WeakPolarHBondContact O-CB 3.48Å; L265-S269 PolarHBondContact O-N 2.91Å; L265-S269 PolarHBondContact O-OG 3.04Å; I266-S269 PolarHBondContact O-N 3.28Å; S267-S269 VanDerWaalsContact C-N 3.34Å; S267-S269 PolarHBondContact O-N 3.21Å; S269-L273 WeakPolarHBondContact O-CB 3.32Å; S269-L273 PolarHBondContact O-N 3.31Å
270	M	89.4	Confident	88.4	Confident	41 Å²	41	45.6 Å²	45.6	20%	0.202	24%	0.244	C	C	.	.	H	α-helix	trans	-67	-45.1	177.1	-169.8	64.5	154.8	0	0	111.5	L105 V108 L112 I266 S267 M272 L273 C274	L105-M270 HydrophobicContact CD1-CE 3.45Å; L105-M270 VanDerWaalsContact CD1-CE 3.45Å; L105-M270 HydrophobicContact CD1-SD 4.2Å; L105-M270 HydrophobicContact CD2-CE 4.36Å; L105-M270 HydrophobicContact CD2-SD 4.12Å; L105-M270 HydrophobicContact CG-CE 3.81Å; L105-M270 HydrophobicContact CG-SD 4.2Å; V108-M270 HydrophobicContact CB-CE 4.2Å; V108-M270 HydrophobicContact CG1-CE 3.68Å; V108-M270 HydrophobicContact CG1-CG 4.32Å; V108-M270 HydrophobicContact CG2-CE 4.42Å; L112-M270 HydrophobicContact CD1-CB 3.8Å; L112-M270 HydrophobicContact CD1-CG 3.48Å; L112-M270 VanDerWaalsContact CD1-CG 3.48Å; I266-M270 WeakPolarHBondContact O-CB 3.39Å; I266-M270 PolarHBondContact O-N 3.47Å; S267-M270 PolarHBondContact O-N 2.84Å; M270-M272 PolarHBondContact O-N 2.76Å; M270-L273 WeakPolarHBondContact O-CB 3.4Å; M270-L273 PolarHBondContact O-N 2.78Å; M270-L273 VanDerWaalsContact O-N 3.11Å; M270-C274 PolarHBondContact O-N 2.99Å; M270-C274 PolarHBondContact O-SG 3.11Å
271	E	91.1	Very high	88.6	Confident	0 Å²	0	46 Å²	46	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-68	-35.6	179.8	-171.8	64.7	-179.5	0	0	112.1	G109 P113 Y169 L173 S267 I268 L273 C274 F275	G109-E271 WeakPolarHBondContact CA-OE2 3.45Å; G109-E271 VanDerWaalsContact O-OE2 3.1Å; P113-E271 HydrophobicContact CG-CG 4.32Å; Y169-E271 HydrophobicContact CD1-CG 4.39Å; Y169-E271 WeakPolarHBondContact CD1-OE1 3.43Å; Y169-E271 VanDerWaalsContact CE1-OE1 3.26Å; Y169-E271 WeakPolarHBondContact CE1-OE1 3.48Å; L173-E271 HydrophobicContact CD1-CG 4.43Å; L173-E271 HydrophobicContact CD2-CB 3.74Å; L173-E271 HydrophobicContact CD2-CG 3.63Å; L173-E271 HydrophobicContact CG-CB 4.41Å; L173-E271 HydrophobicContact CG-CG 3.73Å; S267-E271 WeakPolarHBondContact O-CB 3.39Å; S267-E271 PolarHBondContact O-N 3.26Å; I268-E271 PolarHBondContact O-N 3.23Å; E271-L273 VanDerWaalsContact C-N 3.33Å; E271-L273 PolarHBondContact O-N 3.37Å; E271-C274 WeakPolarHBondContact O-CB 3.48Å; E271-C274 PolarHBondContact O-N 2.97Å; E271-F275 WeakPolarHBondContact O-CB 3.48Å; E271-F275 PolarHBondContact O-N 2.97Å
272	M	92.8	Very high	88.6	Confident	74 Å²	74	47.6 Å²	47.6	37%	0.365	25%	0.25	S	C	.	.	H	α-helix	trans	-62	-40.1	169.5	-77.3	-62.7	-58.7	0	0	111.9	L173 I268 M270 F275 L276	L173-M272 HydrophobicContact CD1-SD 3.62Å; L173-M272 HydrophobicContact CD2-CG 3.81Å; L173-M272 HydrophobicContact CD2-SD 3.85Å; L173-M272 HydrophobicContact CG-SD 4.35Å; I268-M272 HydrophobicContact CG2-CG 4.38Å; I268-M272 VanDerWaalsContact O-CB 3.31Å; I268-M272 WeakPolarHBondContact O-CB 3Å; I268-M272 VanDerWaalsContact O-CG 3.22Å; I268-M272 WeakPolarHBondContact O-CG 3.19Å; I268-M272 PolarHBondContact O-N 3.01Å; M270-M272 PolarHBondContact O-N 2.76Å; M272-F275 PolarHBondContact O-N 2.83Å; M272-L276 WeakPolarHBondContact O-CB 3.27Å; M272-L276 VanDerWaalsContact O-CG 3.28Å; M272-L276 WeakPolarHBondContact O-CG 3.32Å; M272-L276 PolarHBondContact O-N 2.92Å
273	L	93.4	Very high	88.6	Confident	81 Å²	81	52.6 Å²	52.6	42%	0.424	26%	0.263	S	S	.	.	H	α-helix	trans	-65.6	-44.1	175.2	-179.8	59.8	0	0	0	111.4	L105 S269 M270 E271 F275 L276 L277	L105-L273 HydrophobicContact CD2-CB 4.3Å; L105-L273 HydrophobicContact CD2-CD2 3.66Å; L105-L273 HydrophobicContact CD2-CG 3.61Å; S269-L273 WeakPolarHBondContact O-CB 3.32Å; S269-L273 PolarHBondContact O-N 3.31Å; M270-L273 WeakPolarHBondContact O-CB 3.4Å; M270-L273 PolarHBondContact O-N 2.78Å; M270-L273 VanDerWaalsContact O-N 3.11Å; E271-L273 VanDerWaalsContact C-N 3.33Å; E271-L273 PolarHBondContact O-N 3.37Å; L273-F275 VanDerWaalsContact C-N 3.34Å; L273-F275 PolarHBondContact O-N 2.94Å; L273-L276 PolarHBondContact O-N 3.44Å; L273-L277 HydrophobicContact CD1-CD1 4.17Å; L273-L277 HydrophobicContact CD1-CG 4.17Å; L273-L277 HydrophobicContact CG-CD1 4.09Å; L273-L277 WeakPolarHBondContact O-CB 3.38Å; L273-L277 VanDerWaalsContact O-CG 3.32Å; L273-L277 WeakPolarHBondContact O-CG 3.14Å; L273-L277 PolarHBondContact O-N 2.79Å
274	C	91.9	Very high	88.7	Confident	2 Å²	2	53.6 Å²	53.6	1%	0.014	27%	0.271	C	S	.	.	H	α-helix	trans	-56.8	-46	173.4	-64.6	0	0	0	0	111.9	L105 Y169 M270 E271 L277 H278	L105-C274 PolarHBondContact O-SG 3.47Å; Y169-C274 HydrophobicContact CE1-CB 3.78Å; M270-C274 PolarHBondContact O-N 2.99Å; M270-C274 PolarHBondContact O-SG 3.11Å; E271-C274 WeakPolarHBondContact O-CB 3.48Å; E271-C274 PolarHBondContact O-N 2.97Å; C274-L277 PolarHBondContact O-N 3.01Å; C274-H278 WeakPolarHBondContact O-CB 3.2Å; C274-H278 PolarHBondContact O-N 3.37Å
275	F	91.3	Very high	88.4	Confident	37 Å²	37	63.6 Å²	63.6	16%	0.162	31%	0.309	C	S	.	.	H	α-helix	trans	-61.5	-49.3	177	177.5	-113.9	0	0	0	112.3	T166 Y169 L173 E271 M272 L273 L277 H278 L279	T166-F275 HydrophobicContact CG2-CE2 4.14Å; Y169-F275 VanDerWaalsContact CB-CD2 3.48Å; Y169-F275 HydrophobicContact CD1-CB 3.96Å; Y169-F275 HydrophobicContact CD1-CD2 4.34Å; Y169-F275 AromaticContact CD2-CD2 3.89Å; Y169-F275 HydrophobicContact CD2-CD2 3.89Å; Y169-F275 HydrophobicContact CE1-CB 4.37Å; Y169-F275 HydrophobicContact CG-CB 4.16Å; Y169-F275 AromaticContact CG-CD2 3.67Å; Y169-F275 HydrophobicContact CG-CD2 3.67Å; Y169-F275 HydrophobicContact CG-CG 4.38Å; L173-F275 HydrophobicContact CD1-CB 4.3Å; L173-F275 HydrophobicContact CD1-CG 4.48Å; E271-F275 WeakPolarHBondContact O-CB 3.48Å; E271-F275 PolarHBondContact O-N 2.97Å; M272-F275 PolarHBondContact O-N 2.83Å; L273-F275 VanDerWaalsContact C-N 3.34Å; L273-F275 PolarHBondContact O-N 2.94Å; F275-L277 PolarHBondContact O-N 3.37Å; F275-H278 PolarHBondContact O-N 3.07Å; F275-L279 HydrophobicContact CD1-CD1 4.29Å; F275-L279 HydrophobicContact CE1-CD1 3.77Å; F275-L279 HydrophobicContact CE2-CD1 4.46Å; F275-L279 HydrophobicContact CE2-CG 4.49Å; F275-L279 HydrophobicContact CZ-CD1 3.88Å; F275-L279 HydrophobicContact CZ-CD2 4.48Å; F275-L279 HydrophobicContact CZ-CG 4.38Å; F275-L279 WeakPolarHBondContact O-CG 3.41Å; F275-L279 PolarHBondContact O-N 3.38Å; F275-L279 VanDerWaalsContact O-N 3.11Å
276	L	91.9	Very high	88.1	Confident	93 Å²	93	59.6 Å²	59.6	49%	0.487	29%	0.288	S	S	.	.	H	α-helix	trans	-62	-44.1	178.4	-71.1	173.2	0	0	0	111.7	M272 L273 H278 L279 V280	M272-L276 WeakPolarHBondContact O-CB 3.27Å; M272-L276 VanDerWaalsContact O-CG 3.28Å; M272-L276 WeakPolarHBondContact O-CG 3.32Å; M272-L276 PolarHBondContact O-N 2.92Å; L273-L276 PolarHBondContact O-N 3.44Å; L276-H278 VanDerWaalsContact C-N 3.34Å; L276-H278 PolarHBondContact O-N 3.42Å; L276-L279 PolarHBondContact O-N 3.46Å; L276-V280 WeakPolarHBondContact O-CG2 3.41Å; L276-V280 PolarHBondContact O-N 3.03Å; L276-V280 VanDerWaalsContact O-N 3.11Å
277	L	90.6	Very high	87.8	Confident	55 Å²	55	55.2 Å²	55.2	29%	0.288	27%	0.265	S	S	.	.	H	α-helix	trans	-61.8	-40.7	175.1	-73.8	174.5	0	0	0	111.7	A102 L105 L273 C274 F275 L279 V280 V281	A102-L277 HydrophobicContact CB-CB 4.2Å; A102-L277 HydrophobicContact CB-CD1 4.41Å; L105-L277 HydrophobicContact CB-CD1 4.29Å; L105-L277 HydrophobicContact CD2-CD1 3.53Å; L273-L277 HydrophobicContact CD1-CD1 4.17Å; L273-L277 HydrophobicContact CD1-CG 4.17Å; L273-L277 HydrophobicContact CG-CD1 4.09Å; L273-L277 WeakPolarHBondContact O-CB 3.38Å; L273-L277 VanDerWaalsContact O-CG 3.32Å; L273-L277 WeakPolarHBondContact O-CG 3.14Å; L273-L277 PolarHBondContact O-N 2.79Å; C274-L277 PolarHBondContact O-N 3.01Å; F275-L277 PolarHBondContact O-N 3.37Å; L277-L279 VanDerWaalsContact C-N 3.32Å; L277-L279 PolarHBondContact O-N 3.12Å; L277-V280 PolarHBondContact O-N 3.09Å; L277-V281 WeakPolarHBondContact O-CB 3.37Å; L277-V281 VanDerWaalsContact O-CG2 3.29Å; L277-V281 WeakPolarHBondContact O-CG2 3.41Å; L277-V281 PolarHBondContact O-N 2.88Å
278	H	87.3	Confident	87.5	Confident	6 Å²	6	61.6 Å²	61.6	3%	0.028	29%	0.289	C	S	.	.	H	α-helix	trans	-59.5	-41.9	175	-177.5	69.7	0	0	0	112.2	I165 Y169 F216 C274 F275 L276 V280 R282	I165-H278 WeakPolarHBondContact CG2-NE2 3.18Å; Y169-H278 HydrophobicContact CE2-CB 4Å; F216-H278 AromaticContact CE2-ND1 3.6Å; C274-H278 WeakPolarHBondContact O-CB 3.2Å; C274-H278 PolarHBondContact O-N 3.37Å; F275-H278 PolarHBondContact O-N 3.07Å; L276-H278 VanDerWaalsContact C-N 3.34Å; L276-H278 PolarHBondContact O-N 3.42Å; H278-V280 VanDerWaalsContact C-N 3.33Å; H278-V280 PolarHBondContact O-N 3.06Å; H278-R282 VanDerWaalsContact O-CB 3.26Å; H278-R282 WeakPolarHBondContact O-CB 3.41Å; H278-R282 PolarHBondContact O-N 2.77Å
279	L	88.3	Confident	86.9	Confident	40 Å²	40	63 Å²	63	21%	0.209	29%	0.293	C	S	.	.	H	α-helix	trans	-63.7	-35.9	176.6	-64.6	177.4	0	0	0	112.8	F275 L276 L277	F275-L279 HydrophobicContact CD1-CD1 4.29Å; F275-L279 HydrophobicContact CE1-CD1 3.77Å; F275-L279 HydrophobicContact CE2-CD1 4.46Å; F275-L279 HydrophobicContact CE2-CG 4.49Å; F275-L279 HydrophobicContact CZ-CD1 3.88Å; F275-L279 HydrophobicContact CZ-CD2 4.48Å; F275-L279 HydrophobicContact CZ-CG 4.38Å; F275-L279 WeakPolarHBondContact O-CG 3.41Å; F275-L279 PolarHBondContact O-N 3.38Å; F275-L279 VanDerWaalsContact O-N 3.11Å; L276-L279 PolarHBondContact O-N 3.46Å; L277-L279 VanDerWaalsContact C-N 3.32Å; L277-L279 PolarHBondContact O-N 3.12Å
280	V	88.3	Confident	86.3	Confident	100 Å²	100	61.8 Å²	61.8	61%	0.606	28%	0.278	S	S	*	.	H	α-helix	trans	-71.9	-51.4	175.7	173.4	0	0	0	0	111.1	L276 L277 H278 R282 R283 S284	L276-V280 WeakPolarHBondContact O-CG2 3.41Å; L276-V280 PolarHBondContact O-N 3.03Å; L276-V280 VanDerWaalsContact O-N 3.11Å; L277-V280 PolarHBondContact O-N 3.09Å; H278-V280 VanDerWaalsContact C-N 3.33Å; H278-V280 PolarHBondContact O-N 3.06Å; V280-R282 VanDerWaalsContact C-N 3.29Å; V280-R282 PolarHBondContact O-N 2.92Å; V280-R283 WeakPolarHBondContact O-CA 3.41Å; V280-R283 WeakPolarHBondContact O-CB 3.26Å; V280-R283 PolarHBondContact O-N 3.35Å; V280-S284 PolarHBondContact O-N 3.37Å
281	V	86.1	Confident	85.8	Confident	11 Å²	11	60.6 Å²	60.6	7%	0.067	27%	0.273	C	S	.	.	H	α-helix	trans	-54.9	-44.6	178.4	165.5	0	0	0	0	111.1	I99 A102 M103 L277 R283 S284 V287	I99-V281 HydrophobicContact CG2-CG1 4.29Å; A102-V281 HydrophobicContact CB-CG2 3.45Å; A102-V281 VanDerWaalsContact CB-CG2 3.45Å; M103-V281 HydrophobicContact CE-CG1 3.63Å; L277-V281 WeakPolarHBondContact O-CB 3.37Å; L277-V281 VanDerWaalsContact O-CG2 3.29Å; L277-V281 WeakPolarHBondContact O-CG2 3.41Å; L277-V281 PolarHBondContact O-N 2.88Å; V281-R283 PolarHBondContact O-N 3.49Å; V281-S284 VanDerWaalsContact O-CB 3.29Å; V281-S284 WeakPolarHBondContact O-CB 3.41Å; V281-S284 PolarHBondContact O-N 3.32Å; V281-S284 PolarHBondContact O-OG 3.48Å; V281-V287 HydrophobicContact CG1-CG2 3.73Å; V281-V287 WeakPolarHBondContact O-CG2 3.45Å
282	R	82.6	Confident	84.9	Confident	76 Å²	76	61.5 Å²	61.5	29%	0.287	28%	0.282	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.1	-29.6	175	-177	-178.7	69.9	-178.7	2.5	113.6	H278 V280	H278-R282 VanDerWaalsContact O-CB 3.26Å; H278-R282 WeakPolarHBondContact O-CB 3.41Å; H278-R282 PolarHBondContact O-N 2.77Å; V280-R282 VanDerWaalsContact C-N 3.29Å; V280-R282 PolarHBondContact O-N 2.92Å
283	R	83.2	Confident	83.8	Confident	186 Å²	186	62.1 Å²	62.1	70%	0.702	28%	0.284	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.3	-14.9	178.4	-76	-179.3	167.5	155	-3.7	113.5	V280 V281 R288	V280-R283 WeakPolarHBondContact O-CA 3.41Å; V280-R283 WeakPolarHBondContact O-CB 3.26Å; V280-R283 PolarHBondContact O-N 3.35Å; V281-R283 PolarHBondContact O-N 3.49Å; R283-R288 PolarHBondContact O-NH2 3.42Å
284	S	84.2	Confident	82.2	Confident	29 Å²	29	58.7 Å²	58.7	20%	0.203	27%	0.267	C	S	.	.	S	Bend	trans	-59.3	151.9	-179.4	74.9	0	0	0	0	113.1	V280 V281 V287 R288	V280-S284 PolarHBondContact O-N 3.37Å; V281-S284 VanDerWaalsContact O-CB 3.29Å; V281-S284 WeakPolarHBondContact O-CB 3.41Å; V281-S284 PolarHBondContact O-N 3.32Å; V281-S284 PolarHBondContact O-OG 3.48Å; S284-V287 WeakPolarHBondContact OG-CB 3.15Å; S284-V287 VanDerWaalsContact OG-CG2 3.28Å; S284-V287 WeakPolarHBondContact OG-CG2 3.24Å; S284-V287 PolarHBondContact OG-N 3.31Å; S284-R288 PolarHBondContact O-N 3.44Å
285	R	78.4	Confident	80.8	Confident	218 Å²	218	63.3 Å²	63.3	82%	0.823	29%	0.288	S	S	*	.	H	α-helix	trans	-69.1	-39.6	175.7	-67.8	-175.2	179	-171.5	-0.5	111.6	V287 R288 Y289	R285-V287 PolarHBondContact O-N 2.99Å; R285-R288 PolarHBondContact O-N 2.93Å; R285-Y289 PolarHBondContact O-N 3.37Å
286	F	82.4	Confident	79.1	Confident	8 Å²	8	64.1 Å²	64.1	4%	0.035	31%	0.307	C	S	.	.	H	α-helix	trans	-50.5	-55.1	175.4	-175.6	-80.3	0	0	0	112.6	P92 D94 I99 L223 Y227 R288 Y289 Y290	P92-F286 HydrophobicContact CB-CB 4.47Å; P92-F286 HydrophobicContact CB-CD2 4.26Å; P92-F286 HydrophobicContact CG-CD2 4.25Å; P92-F286 WeakPolarHBondContact O-CD2 3.38Å; P92-F286 WeakPolarHBondContact O-CE2 3.35Å; D94-F286 HydrophobicContact CB-CE2 4.29Å; I99-F286 HydrophobicContact CD1-CB 3.4Å; I99-F286 VanDerWaalsContact CD1-CB 3.4Å; I99-F286 HydrophobicContact CD1-CD1 3.61Å; I99-F286 HydrophobicContact CD1-CD2 4.15Å; I99-F286 HydrophobicContact CD1-CE1 4.47Å; I99-F286 HydrophobicContact CD1-CG 3.45Å; I99-F286 VanDerWaalsContact CD1-CG 3.45Å; L223-F286 HydrophobicContact CD2-CE1 4.44Å; Y227-F286 AromaticContact CE2-CE1 3.78Å; Y227-F286 HydrophobicContact CE2-CE1 3.78Å; Y227-F286 AromaticContact CE2-CZ 3.53Å; Y227-F286 HydrophobicContact CE2-CZ 3.53Å; Y227-F286 AromaticContact CZ-CE1 3.85Å; Y227-F286 AromaticContact CZ-CZ 3.66Å; Y227-F286 WeakPolarHBondContact OH-CZ 3.29Å; F286-R288 VanDerWaalsContact C-N 3.35Å; F286-R288 PolarHBondContact O-N 2.99Å; F286-Y289 WeakPolarHBondContact O-CB 3.45Å; F286-Y289 PolarHBondContact O-N 2.9Å; F286-Y290 AromaticContact CD1-CD2 3.98Å; F286-Y290 HydrophobicContact CD1-CD2 3.98Å; F286-Y290 HydrophobicContact CD1-CE2 4.26Å; F286-Y290 HydrophobicContact CD2-CE2 4.27Å; F286-Y290 AromaticContact CE1-CD2 3.63Å; F286-Y290 HydrophobicContact CE1-CD2 3.63Å; F286-Y290 AromaticContact CE1-CE2 3.7Å; F286-Y290 HydrophobicContact CE1-CE2 3.7Å; F286-Y290 HydrophobicContact CE2-CD2 4.37Å; F286-Y290 AromaticContact CE2-CE2 3.7Å; F286-Y290 HydrophobicContact CE2-CE2 3.7Å; F286-Y290 HydrophobicContact CG-CD2 4.47Å; F286-Y290 HydrophobicContact CG-CE2 4.5Å; F286-Y290 AromaticContact CZ-CD2 3.83Å; F286-Y290 HydrophobicContact CZ-CD2 3.83Å; F286-Y290 AromaticContact CZ-CE2 3.35Å; F286-Y290 HydrophobicContact CZ-CE2 3.35Å; F286-Y290 WeakPolarHBondContact O-CD2 3.5Å; F286-Y290 PolarHBondContact O-N 3.02Å
287	V	79.9	Confident	77.1	Confident	1 Å²	1	67.1 Å²	67.1	1%	0.006	32%	0.316	C	S	.	.	H	α-helix	trans	-63.1	-42.8	-178.5	164.2	0	0	0	0	111.5	Y219 V281 S284 R285 Y289 Y290 T291	Y219-V287 HydrophobicContact CE2-CG1 3.99Å; Y219-V287 WeakPolarHBondContact OH-CG1 3.23Å; Y219-V287 WeakPolarHBondContact OH-CG2 3.46Å; V281-V287 HydrophobicContact CG1-CG2 3.73Å; V281-V287 WeakPolarHBondContact O-CG2 3.45Å; S284-V287 WeakPolarHBondContact OG-CB 3.15Å; S284-V287 VanDerWaalsContact OG-CG2 3.28Å; S284-V287 WeakPolarHBondContact OG-CG2 3.24Å; S284-V287 PolarHBondContact OG-N 3.31Å; R285-V287 PolarHBondContact O-N 2.99Å; V287-Y289 VanDerWaalsContact C-N 3.28Å; V287-Y289 PolarHBondContact O-N 2.71Å; V287-Y290 PolarHBondContact O-N 2.96Å; V287-T291 HydrophobicContact CG1-CG2 4.29Å; V287-T291 WeakPolarHBondContact O-CB 3.48Å; V287-T291 WeakPolarHBondContact O-CG2 3.48Å; V287-T291 PolarHBondContact O-N 3.36Å; V287-T291 PolarHBondContact O-OG1 3.35Å
288	R	81.1	Confident	74.6	Confident	136 Å²	136	66.3 Å²	66.3	51%	0.513	32%	0.321	S	S	.	.	H	α-helix	trans	-63.9	-34.8	179	-166.9	-179.7	-58.4	96.1	11.9	112.1	R283 S284 R285 F286 T291 G292	R283-R288 PolarHBondContact O-NH2 3.42Å; S284-R288 PolarHBondContact O-N 3.44Å; R285-R288 PolarHBondContact O-N 2.93Å; F286-R288 VanDerWaalsContact C-N 3.35Å; F286-R288 PolarHBondContact O-N 2.99Å; R288-T291 PolarHBondContact O-OG1 2.99Å; R288-G292 PolarHBondContact O-N 2.95Å
289	Y	79.7	Confident	72.1	Confident	53 Å²	53	74.5 Å²	74.5	21%	0.208	36%	0.359	C	S	.	.	H	α-helix	trans	-62.1	-60	175.3	179.8	-90.8	0	0	0	110.9	Q89 P92 R285 F286 V287 T291 G292 H293	Q89-Y289 HydrophobicContact CB-CE2 4.24Å; P92-Y289 HydrophobicContact CG-CD1 3.85Å; P92-Y289 HydrophobicContact CG-CD2 4.32Å; P92-Y289 HydrophobicContact CG-CG 3.73Å; R285-Y289 PolarHBondContact O-N 3.37Å; F286-Y289 WeakPolarHBondContact O-CB 3.45Å; F286-Y289 PolarHBondContact O-N 2.9Å; V287-Y289 VanDerWaalsContact C-N 3.28Å; V287-Y289 PolarHBondContact O-N 2.71Å; Y289-T291 PolarHBondContact O-N 3.12Å; Y289-G292 PolarHBondContact O-N 3.41Å; Y289-H293 AromaticContact CD2-CE1 3.56Å; Y289-H293 AromaticContact CD2-ND1 3.93Å; Y289-H293 AromaticContact CE1-ND1 4Å; Y289-H293 AromaticContact CE2-CE1 3.25Å; Y289-H293 WeakPolarHBondContact CE2-CE1 3.34Å; Y289-H293 AromaticContact CE2-ND1 3.92Å; Y289-H293 AromaticContact CG-ND1 3.96Å; Y289-H293 AromaticContact CZ-CE1 3.48Å; Y289-H293 VanDerWaalsContact CZ-CE1 3.48Å; Y289-H293 AromaticContact CZ-ND1 3.95Å; Y289-H293 AromaticContact CZ-NE2 3.96Å; Y289-H293 PolarHBondContact O-N 3.02Å; Y289-H293 PolarHBondContact O-ND1 3.29Å
290	Y	78.4	Confident	69.8	Low	51 Å²	51	78.7 Å²	78.7	20%	0.2	39%	0.386	C	S	.	.	H	α-helix	trans	-63.9	-39.7	-177.9	-77	-78	0	0	0	113.2	I91 L223 P224 F286 V287 A294	I91-Y290 VanDerWaalsContact CG2-OH 3.28Å; I91-Y290 WeakPolarHBondContact CG2-OH 3.35Å; L223-Y290 HydrophobicContact CD2-CD2 4.37Å; L223-Y290 HydrophobicContact CD2-CG 4.1Å; P224-Y290 HydrophobicContact CG-CD1 4.5Å; P224-Y290 HydrophobicContact CG-CE1 3.81Å; P224-Y290 HydrophobicContact CG-CE2 4.29Å; F286-Y290 AromaticContact CD1-CD2 3.98Å; F286-Y290 HydrophobicContact CD1-CD2 3.98Å; F286-Y290 HydrophobicContact CD1-CE2 4.26Å; F286-Y290 HydrophobicContact CD2-CE2 4.27Å; F286-Y290 AromaticContact CE1-CD2 3.63Å; F286-Y290 HydrophobicContact CE1-CD2 3.63Å; F286-Y290 AromaticContact CE1-CE2 3.7Å; F286-Y290 HydrophobicContact CE1-CE2 3.7Å; F286-Y290 HydrophobicContact CE2-CD2 4.37Å; F286-Y290 AromaticContact CE2-CE2 3.7Å; F286-Y290 HydrophobicContact CE2-CE2 3.7Å; F286-Y290 HydrophobicContact CG-CD2 4.47Å; F286-Y290 HydrophobicContact CG-CE2 4.5Å; F286-Y290 AromaticContact CZ-CD2 3.83Å; F286-Y290 HydrophobicContact CZ-CD2 3.83Å; F286-Y290 AromaticContact CZ-CE2 3.35Å; F286-Y290 HydrophobicContact CZ-CE2 3.35Å; F286-Y290 WeakPolarHBondContact O-CD2 3.5Å; F286-Y290 PolarHBondContact O-N 3.02Å; V287-Y290 PolarHBondContact O-N 2.96Å; Y290-A294 PolarHBondContact O-N 2.96Å; Y290-A294 VanDerWaalsContact O-N 3.11Å
291	T	78.4	Confident	67	Low	16 Å²	16	82.6 Å²	82.6	10%	0.098	40%	0.395	C	S	.	.	H	α-helix	trans	-69.6	-35.3	177.4	53.2	0	0	0	0	113	Y219 M222 V287 R288 Y289 Q295	Y219-T291 HydrophobicContact CD2-CG2 4.18Å; Y219-T291 HydrophobicContact CE2-CG2 3.79Å; M222-T291 HydrophobicContact CE-CG2 4.28Å; M222-T291 HydrophobicContact SD-CG2 4.33Å; V287-T291 HydrophobicContact CG1-CG2 4.29Å; V287-T291 WeakPolarHBondContact O-CB 3.48Å; V287-T291 WeakPolarHBondContact O-CG2 3.48Å; V287-T291 PolarHBondContact O-N 3.36Å; V287-T291 PolarHBondContact O-OG1 3.35Å; R288-T291 PolarHBondContact O-OG1 2.99Å; Y289-T291 PolarHBondContact O-N 3.12Å; T291-Q295 WeakPolarHBondContact O-CB 3.47Å; T291-Q295 VanDerWaalsContact O-CG 3.3Å; T291-Q295 WeakPolarHBondContact O-CG 3.28Å; T291-Q295 PolarHBondContact O-N 3.09Å
292	G	71.8	Confident	64.3	Low	19 Å²	19	88.1 Å²	88.1	20%	0.196	43%	0.433	C	S	.	.	H	α-helix	trans	-66.6	-42.3	174.9	0	0	0	0	0	113.2	R288 Y289 Q295 K297	R288-G292 PolarHBondContact O-N 2.95Å; Y289-G292 PolarHBondContact O-N 3.41Å; G292-Q295 PolarHBondContact O-N 2.99Å; G292-K297 PolarHBondContact O-N 2.71Å; G292-K297 VanDerWaalsContact O-N 3.08Å
293	H	70.1	Confident	61.9	Low	87 Å²	87	92.3 Å²	92.3	40%	0.403	46%	0.456	S	S	.	.	H	α-helix	trans	-65.3	-47.7	177.4	-77.5	79.8	0	0	0	112.2	Y289 Q295 G296	Y289-H293 AromaticContact CD2-CE1 3.56Å; Y289-H293 AromaticContact CD2-ND1 3.93Å; Y289-H293 AromaticContact CE1-ND1 4Å; Y289-H293 AromaticContact CE2-CE1 3.25Å; Y289-H293 WeakPolarHBondContact CE2-CE1 3.34Å; Y289-H293 AromaticContact CE2-ND1 3.92Å; Y289-H293 AromaticContact CG-ND1 3.96Å; Y289-H293 AromaticContact CZ-CE1 3.48Å; Y289-H293 VanDerWaalsContact CZ-CE1 3.48Å; Y289-H293 AromaticContact CZ-ND1 3.95Å; Y289-H293 AromaticContact CZ-NE2 3.96Å; Y289-H293 PolarHBondContact O-N 3.02Å; Y289-H293 PolarHBondContact O-ND1 3.29Å; H293-Q295 PolarHBondContact O-N 3.1Å; H293-G296 PolarHBondContact O-N 2.82Å; H293-G296 VanDerWaalsContact O-N 3.11Å
294	A	60.6	Low	59.4	Low	8 Å²	8	88 Å²	88	7%	0.066	45%	0.446	C	S	.	.	H	α-helix	trans	-70.7	-11.6	178.8	0	0	0	0	0	114	M222 Y290 P502 E503	M222-A294 HydrophobicContact CB-CB 4.22Å; M222-A294 HydrophobicContact CE-CB 3.67Å; M222-A294 HydrophobicContact CG-CB 4.34Å; Y290-A294 PolarHBondContact O-N 2.96Å; Y290-A294 VanDerWaalsContact O-N 3.11Å; A294-P502 HydrophobicContact CB-CB 4.27Å; A294-E503 WeakPolarHBondContact O-CA 3.28Å
295	Q	62.6	Low	57.3	Low	99 Å²	99	92 Å²	92	46%	0.463	47%	0.472	S	S	.	.	T	Hydrogen-bonded Turn	trans	-98.4	14.7	170.9	-70.8	-177.2	-3.3	0	0	113.6	M222 T291 G292 H293 K297	M222-Q295 HydrophobicContact CE-CG 3.89Å; T291-Q295 WeakPolarHBondContact O-CB 3.47Å; T291-Q295 VanDerWaalsContact O-CG 3.3Å; T291-Q295 WeakPolarHBondContact O-CG 3.28Å; T291-Q295 PolarHBondContact O-N 3.09Å; G292-Q295 PolarHBondContact O-N 2.99Å; H293-Q295 PolarHBondContact O-N 3.1Å; Q295-K297 PolarHBondContact O-N 2.94Å; Q295-K297 VanDerWaalsContact O-N 3.16Å
296	G	55.7	Low	55.2	Low	54 Å²	54	91 Å²	91	56%	0.557	47%	0.468	S	S	*	.	T	Hydrogen-bonded Turn	trans	71	5.9	176.4	0	0	0	0	0	115.4	H293 G298	H293-G296 PolarHBondContact O-N 2.82Å; H293-G296 VanDerWaalsContact O-N 3.11Å; G296-G298 PolarHBondContact O-N 3.36Å
297	K	49.6	Very low	53	Low	156 Å²	156	96 Å²	96	68%	0.678	50%	0.495	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.3	16.2	-178.4	-65.9	175.8	-178.5	164.5	0	113.4	G292 Q295	G292-K297 PolarHBondContact O-N 2.71Å; G292-K297 VanDerWaalsContact O-N 3.08Å; Q295-K297 PolarHBondContact O-N 2.94Å; Q295-K297 VanDerWaalsContact O-N 3.16Å
298	G	38.9	Very low	51.3	Low	39 Å²	39	100.6 Å²	100.6	40%	0.402	53%	0.533	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102.8	2.1	-168	0	0	0	0	0	116.4	G296	G296-G298 PolarHBondContact O-N 3.36Å
299	Q	34.1	Very low	49.1	Very low	177 Å²	177	96.9 Å²	96.9	83%	0.827	54%	0.538	S	S	*	.			trans	-115.1	76.8	167.7	-88.6	-166.4	-6.3	0	0	110.9	K301	Q299-K301 PolarHBondContact O-N 3.18Å
300	V	39.8	Very low	47.5	Very low	128 Å²	128	101.9 Å²	101.9	78%	0.776	57%	0.574	S	S	*	*			trans	-77.4	102.4	147.6	178.3	0	0	0	0	105.4	C302	V300-C302 PolarHBondContact O-N 2.91Å; V300-C302 VanDerWaalsContact O-N 3.11Å
301	K	30.3	Very low	45.2	Very low	183 Å²	183	102.3 Å²	102.3	80%	0.796	59%	0.593	S	S	*	*	P	Polyproline II helix	trans	-57.7	117.1	163.4	-85.8	-175.8	172.6	-179	0	107.1	Q299 H303	Q299-K301 PolarHBondContact O-N 3.18Å; K301-H303 PolarHBondContact O-N 3.4Å
302	C	29.5	Very low	43.1	Very low	127 Å²	127	113.2 Å²	113.2	86%	0.858	64%	0.635	S	S	*	*	P	Polyproline II helix	trans	-58.9	125.8	166.9	-81	0	0	0	0	108.1	V300 D304	V300-C302 PolarHBondContact O-N 2.91Å; V300-C302 VanDerWaalsContact O-N 3.11Å; C302-D304 PolarHBondContact O-N 3.5Å
303	H	30.1	Very low	41.1	Very low	164 Å²	164	122 Å²	122	76%	0.759	66%	0.662	S	S	*	*	P	Polyproline II helix	trans	-73	119.7	176.8	179.3	55.6	0	0	0	108.4	K301 P305	K301-H303 PolarHBondContact O-N 3.4Å; H303-P305 VanDerWaalsContact O-CD 3.32Å; H303-P305 WeakPolarHBondContact O-CD 3.21Å
304	D	32.5	Very low	39.4	Very low	95 Å²	95	123.6 Å²	123.6	51%	0.508	68%	0.677	S	S	.	*	P	Polyproline II helix	trans	-62.3	119.5	172.6	-177.1	-13.6	0	0	0	109.2	C302 R306	C302-D304 PolarHBondContact O-N 3.5Å; D304-R306 PolarHBondContact O-N 2.9Å; D304-R306 WeakPolarHBondContact OD1-CB 3.48Å; D304-R306 WeakPolarHBondContact OD1-CG 3.44Å; D304-R306 PolarHBondContact OD1-N 3.21Å
305	P	38.5	Very low	37.9	Very low	114 Å²	114	131.1 Å²	131.1	74%	0.74	71%	0.711	S	S	*	*	T	Hydrogen-bonded Turn	trans	-66.8	-4.6	-179.1	-20.3	33.6	0	0	0	114.9	H303	H303-P305 VanDerWaalsContact O-CD 3.32Å; H303-P305 WeakPolarHBondContact O-CD 3.21Å
306	R	35.6	Very low	36.3	Very low	196 Å²	196	133.8 Å²	133.8	74%	0.74	72%	0.723	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.8	-9.6	-172.2	-59.7	-177.8	-164.9	-174.2	9.2	114.9	D304 A308	D304-R306 PolarHBondContact O-N 2.9Å; D304-R306 WeakPolarHBondContact OD1-CB 3.48Å; D304-R306 WeakPolarHBondContact OD1-CG 3.44Å; D304-R306 PolarHBondContact OD1-N 3.21Å; R306-A308 PolarHBondContact O-N 3.18Å
307	D	35	Very low	35.1	Very low	113 Å²	113	138.1 Å²	138.1	60%	0.604	73%	0.733	S	S	*	*			trans	-82.9	32.7	178.5	-132.8	23.5	0	0	0	112.8	G309 R313	D307-G309 PolarHBondContact O-N 3.12Å; D307-R313 IonicContact OD2-NH1 3.28Å; D307-R313 PolarHBondContact OD2-NH1 3.11Å
308	A	44.5	Very low	34.3	Very low	97 Å²	97	135.8 Å²	135.8	80%	0.802	73%	0.732	S	S	*	*			trans	-76.2	43.6	171.1	0	0	0	0	0	112.2	R306	R306-A308 PolarHBondContact O-N 3.18Å
309	G	35.7	Very low	33.9	Very low	59 Å²	59	139.6 Å²	139.6	61%	0.608	75%	0.748	S	S	*	*			trans	-94.3	126.1	173.5	0	0	0	0	0	110.7	D307 G311	D307-G309 PolarHBondContact O-N 3.12Å; G309-G311 PolarHBondContact O-N 2.89Å
310	T	45.3	Very low	33.8	Very low	157 Å²	157	136 Å²	136	96%	0.963	75%	0.748	S	S	*	*			trans	-57.2	103.6	-176.8	48.5	0	0	0	0	112.9
311	G	31.4	Very low	33.4	Very low	60 Å²	60	138 Å²	138	62%	0.619	75%	0.749	S	S	*	*			trans	-163.8	120.9	172.4	0	0	0	0	0	111.3	G309 R313	G309-G311 PolarHBondContact O-N 2.89Å; G311-R313 PolarHBondContact O-N 3.45Å
312	Y	34.4	Very low	33.5	Very low	246 Å²	246	138.2 Å²	138.2	97%	0.965	75%	0.753	S	S	*	*			trans	-60	105	172.3	-94.8	-103.8	0	0	0	109.9
313	R	29.6	Very low	33.6	Very low	204 Å²	204	138.2 Å²	138.2	77%	0.77	75%	0.749	S	S	*	*			trans	-104.3	117	163.8	-84.3	-172.7	-177.4	145.2	3.9	109.5	D307 G311 H315	D307-R313 IonicContact OD2-NH1 3.28Å; D307-R313 PolarHBondContact OD2-NH1 3.11Å; G311-R313 PolarHBondContact O-N 3.45Å; R313-H315 PolarHBondContact O-N 2.89Å
314	V	32.9	Very low	33.7	Very low	119 Å²	119	137.9 Å²	137.9	72%	0.721	75%	0.751	S	S	*	*			trans	-66.9	121.2	167.6	176.6	0	0	0	0	108.1	H316	V314-H316 PolarHBondContact O-N 3.47Å
315	H	29.5	Very low	33.5	Very low	167 Å²	167	143 Å²	143	77%	0.773	77%	0.769	S	S	*	*			trans	-66.7	100.1	171.1	-98.7	-99.6	0	0	0	109.8	R313 D317	R313-H315 PolarHBondContact O-N 2.89Å; H315-D317 PolarHBondContact O-N 3.4Å
316	H	30.3	Very low	33	Very low	154 Å²	154	141.3 Å²	141.3	71%	0.713	77%	0.772	S	S	*	*			trans	-88.7	78.6	160.6	-93.5	-68.6	0	0	0	109.4	V314 V318	V314-H316 PolarHBondContact O-N 3.47Å; H316-V318 HydrophobicContact CB-CG2 4.25Å; H316-V318 PolarHBondContact O-N 3.05Å
317	D	30.6	Very low	32.6	Very low	145 Å²	145	140.5 Å²	140.5	78%	0.775	78%	0.783	S	S	*	*			trans	-70.9	80.2	158.2	-83.6	-8.5	0	0	0	108.2	H315	H315-D317 PolarHBondContact O-N 3.4Å
318	V	31.6	Very low	32.2	Very low	107 Å²	107	138.3 Å²	138.3	65%	0.648	79%	0.787	S	S	*	*			trans	-93.8	88.8	166	-177.3	0	0	0	0	107.2	H316 A320	H316-V318 HydrophobicContact CB-CG2 4.25Å; H316-V318 PolarHBondContact O-N 3.05Å; V318-A320 PolarHBondContact O-N 3.49Å
319	T	30.6	Very low	31.2	Very low	120 Å²	120	137.3 Å²	137.3	74%	0.736	79%	0.786	S	S	*	*			trans	-54.6	117.7	151.6	37.4	0	0	0	0	107.7	E321	T319-E321 PolarHBondContact O-N 2.91Å
320	A	31.7	Very low	30.8	Very low	102 Å²	102	141.7 Å²	141.7	84%	0.843	80%	0.801	S	S	*	*			trans	-72.4	79.7	174.6	0	0	0	0	0	110.2	V318	V318-A320 PolarHBondContact O-N 3.49Å
321	E	31.8	Very low	29.9	Very low	168 Å²	168	138.6 Å²	138.6	79%	0.785	79%	0.792	S	S	*	*			trans	-83.7	136.6	155.3	-72.4	-171.1	143.6	0	0	108.6	T319 V323	T319-E321 PolarHBondContact O-N 2.91Å; E321-V323 PolarHBondContact O-N 2.88Å
322	E	32.3	Very low	30.3	Very low	189 Å²	189	141.8 Å²	141.8	88%	0.883	80%	0.801	S	S	*	*			trans	-64	118.6	-174.9	-65.5	179.6	126.7	0	0	111.9	I324	E322-I324 PolarHBondContact O-N 2.87Å
323	V	31.3	Very low	29.9	Very low	126 Å²	126	134.7 Å²	134.7	76%	0.764	79%	0.788	S	S	*	*			trans	-82.3	100.8	176	180	0	0	0	0	110.1	E321	E321-V323 PolarHBondContact O-N 2.88Å
324	I	31.8	Very low	29.7	Very low	157 Å²	157	130.1 Å²	130.1	81%	0.805	79%	0.787	S	S	*	*			trans	-83.8	127	165.3	-60.3	178.2	0	0	0	108.8	E322	E322-I324 PolarHBondContact O-N 2.87Å
325	F	29.8	Very low	29.3	Very low	202 Å²	202	129.2 Å²	129.2	89%	0.886	79%	0.786	S	S	*	*			trans	-68.7	138.4	-174.8	-81.2	-94.9	0	0	0	114.1
326	G	27.6	Very low	29.1	Very low	79 Å²	79	130 Å²	130	81%	0.814	79%	0.79	S	S	*	*			trans	-153.6	147	170.2	0	0	0	0	0	110.8
327	N	26.7	Very low	28.9	Very low	179 Å²	179	132.3 Å²	132.3	96%	0.957	80%	0.801	S	S	*	*			trans	-115	153.8	-153.7	-169.5	28.9	0	0	0	115.5
328	G	26.6	Very low	28.7	Very low	68 Å²	68	129.4 Å²	129.4	70%	0.701	81%	0.806	S	S	*	*			trans	94.9	124.7	175.6	0	0	0	0	0	113.7
329	G	24.8	Very low	28.5	Very low	75 Å²	75	132.8 Å²	132.8	77%	0.773	81%	0.814	S	S	*	*				92.4	125.9	58.6	0	0	0	0	0	108.6
330	T	25.4	Very low	28.4	Very low	151 Å²	151	136.3 Å²	136.3	93%	0.926	82%	0.822	S	S	*	*			cis	-159.1	163.3	23.6	27.2	0	0	0	0	111
331	A	27.7	Very low	28.4	Very low	93 Å²	93	138.3 Å²	138.3	77%	0.769	82%	0.818	S	S	*	*			trans	-118.3	153.7	164.5	0	0	0	0	0	110.1
332	P	39.2	Very low	28.2	Very low	126 Å²	126	140 Å²	140	82%	0.818	82%	0.824	S	S	*	*				-150.2	-172.9	99.4	38.7	-20.6	0	0	0	113
333	S	25.2	Very low	28.7	Very low	98 Å²	98	137.7 Å²	137.7	69%	0.685	82%	0.822	S	S	*	*			cis	-169.8	159	-38.3	59.5	0	0	0	0	109.4
334	S	25.6	Very low	28.6	Very low	108 Å²	108	134.1 Å²	134.1	76%	0.755	81%	0.811	S	S	*	*			trans	57.7	156.2	154.3	54.4	0	0	0	0	119.5
335	S	24.6	Very low	28.8	Very low	100 Å²	100	130.1 Å²	130.1	70%	0.699	81%	0.809	S	S	*	*			cis	-164.3	159.3	-10.3	35.2	0	0	0	0	106.1
336	E	26.8	Very low	28.9	Very low	184 Å²	184	126.1 Å²	126.1	86%	0.86	80%	0.801	S	S	*	*				176.4	-175.1	85.9	-87	-169.4	164.3	0	0	110.7
337	E	24.8	Very low	29.3	Very low	202 Å²	202	132.9 Å²	132.9	94%	0.944	80%	0.803	S	S	*	*			trans	-94.4	170.2	-154.1	-53.7	173.3	136.7	0	0	116.3
338	G	27.7	Very low	29.8	Very low	84 Å²	84	129.1 Å²	129.1	87%	0.866	79%	0.787	S	S	*	*			trans	166.7	103	167.2	0	0	0	0	0	113.8
339	H	26.8	Very low	30.1	Very low	177 Å²	177	135.2 Å²	135.2	82%	0.819	79%	0.788	S	S	*	*			trans	-107.7	134.3	178.8	-132.6	-61.3	0	0	0	109.6
340	E	27.6	Very low	30.7	Very low	195 Å²	195	140.4 Å²	140.4	91%	0.911	79%	0.79	S	S	*	*			trans	-168.3	152	145.1	-115	175.3	-168	0	0	112
341	D	31.6	Very low	31.3	Very low	143 Å²	143	138.7 Å²	138.7	77%	0.765	78%	0.775	S	S	*	*			trans	-91.9	138.8	-165.2	-63.2	-60.2	0	0	0	114.3
342	F	28.7	Very low	31.7	Very low	205 Å²	205	137.7 Å²	137.7	90%	0.899	77%	0.767	S	S	*	*			trans	-153.5	149.6	140.2	-150	-103.3	0	0	0	114.3	G344	F342-G344 PolarHBondContact O-N 3.38Å
343	V	42.1	Very low	31.5	Very low	139 Å²	139	137.4 Å²	137.4	84%	0.842	77%	0.765	S	S	*	*			trans	-78.2	116.3	-173.9	176.4	0	0	0	0	111.9
344	G	30.5	Very low	31.9	Very low	52 Å²	52	142.3 Å²	142.3	54%	0.536	77%	0.774	S	S	.	*	S	Bend	trans	-166.3	139.3	165	0	0	0	0	0	107.9	F342 T346	F342-G344 PolarHBondContact O-N 3.38Å; G344-T346 VanDerWaalsContact C-N 3.35Å; G344-T346 PolarHBondContact O-N 3.27Å; G344-T346 PolarHBondContact O-OG1 3.46Å
345	G	34.3	Very low	32.5	Very low	73 Å²	73	141.1 Å²	141.1	75%	0.753	77%	0.77	S	S	*	*			trans	-64.5	89.7	-175	0	0	0	0	0	112.4	Y347	G345-Y347 PolarHBondContact O-N 2.98Å
346	T	32.1	Very low	32.9	Very low	117 Å²	117	145.9 Å²	145.9	72%	0.718	78%	0.779	S	S	*	*			trans	-67.9	100.8	180	-55.7	0	0	0	0	109.6	G344 V348	G344-T346 VanDerWaalsContact C-N 3.35Å; G344-T346 PolarHBondContact O-N 3.27Å; G344-T346 PolarHBondContact O-OG1 3.46Å; T346-V348 VanDerWaalsContact C-N 3.27Å; T346-V348 HydrophobicContact CG2-CG2 4.11Å; T346-V348 PolarHBondContact O-N 2.93Å
347	Y	36.6	Very low	33.6	Very low	222 Å²	222	144.3 Å²	144.3	87%	0.871	78%	0.775	S	S	*	*			trans	-62.6	94.5	161	-72.7	-91.2	0	0	0	107.8	G345 R349	G345-Y347 PolarHBondContact O-N 2.98Å; Y347-R349 PolarHBondContact O-N 3.03Å
348	V	36.3	Very low	34.1	Very low	100 Å²	100	145.7 Å²	145.7	61%	0.606	77%	0.771	S	S	*	*			trans	-67.9	86.4	169.5	-177	0	0	0	0	107.1	T346 F350	T346-V348 VanDerWaalsContact C-N 3.27Å; T346-V348 HydrophobicContact CG2-CG2 4.11Å; T346-V348 PolarHBondContact O-N 2.93Å; V348-F350 VanDerWaalsContact C-N 3.29Å; V348-F350 HydrophobicContact CG1-CD2 4.14Å; V348-F350 HydrophobicContact CG1-CE2 3.98Å; V348-F350 HydrophobicContact CG1-CZ 4.42Å; V348-F350 PolarHBondContact O-N 3.27Å
349	R	34.4	Very low	34.9	Very low	196 Å²	196	149.2 Å²	149.2	74%	0.74	76%	0.763	S	S	*	*			trans	-65.6	97.7	167.1	-172.9	-176.1	-174.4	97.9	6.8	106.2	Y347 D351	Y347-R349 PolarHBondContact O-N 3.03Å; R349-D351 WeakPolarHBondContact CD-OD1 3.37Å; R349-D351 IonicContact CZ-OD1 3.53Å; R349-D351 IonicContact NE-OD1 2.89Å; R349-D351 PolarHBondContact NE-OD1 3.35Å; R349-D351 IonicContact NE-OD2 2.7Å; R349-D351 IonicContact NH2-OD1 3.22Å; R349-D351 PolarHBondContact O-N 3.44Å
350	F	36.6	Very low	35.9	Very low	183 Å²	183	146.1 Å²	146.1	80%	0.803	76%	0.761	S	S	*	*			trans	-62.2	85.9	158.1	-76.2	-87.3	0	0	0	107	V348 A352	V348-F350 VanDerWaalsContact C-N 3.29Å; V348-F350 HydrophobicContact CG1-CD2 4.14Å; V348-F350 HydrophobicContact CG1-CE2 3.98Å; V348-F350 HydrophobicContact CG1-CZ 4.42Å; V348-F350 PolarHBondContact O-N 3.27Å; F350-A352 PolarHBondContact O-N 3.2Å
351	D	38.2	Very low	37.3	Very low	115 Å²	115	142.6 Å²	142.6	62%	0.615	74%	0.739	S	S	*	*			trans	-67.7	75.6	156.1	-81.3	-35.1	0	0	0	106.3	R349 P353	R349-D351 WeakPolarHBondContact CD-OD1 3.37Å; R349-D351 IonicContact CZ-OD1 3.53Å; R349-D351 IonicContact NE-OD1 2.89Å; R349-D351 PolarHBondContact NE-OD1 3.35Å; R349-D351 IonicContact NE-OD2 2.7Å; R349-D351 IonicContact NH2-OD1 3.22Å; R349-D351 PolarHBondContact O-N 3.44Å; D351-P353 VanDerWaalsContact O-N 3.09Å
352	A	36.4	Very low	38.8	Very low	73 Å²	73	139.5 Å²	139.5	60%	0.603	73%	0.727	S	S	*	*			trans	-47	121.7	162.2	0	0	0	0	0	105.5	F350 K354	F350-A352 PolarHBondContact O-N 3.2Å; A352-K354 PolarHBondContact O-N 3.18Å
353	P	35.3	Very low	40.9	Very low	120 Å²	120	131.2 Å²	131.2	78%	0.779	70%	0.699	S	S	*	*			trans	-54.9	120	-179.6	22.3	-32	0	0	0	105.5	D351 A355	D351-P353 VanDerWaalsContact O-N 3.09Å; P353-A355 PolarHBondContact O-N 3.45Å
354	K	32.6	Very low	42.5	Very low	201 Å²	201	129 Å²	129	87%	0.874	69%	0.686	S	S	*	*			trans	-58.9	93.5	174.7	-75.8	178.8	-179.2	172.1	0	105.7	A352 K356	A352-K354 PolarHBondContact O-N 3.18Å; K354-K356 PolarHBondContact O-N 3.1Å
355	A	38.3	Very low	44.7	Very low	82 Å²	82	136.9 Å²	136.9	68%	0.678	70%	0.699	S	S	*	*			trans	-50.6	114.6	170.8	0	0	0	0	0	103.3	P353 I357	P353-A355 PolarHBondContact O-N 3.45Å; A355-I357 PolarHBondContact O-N 3.31Å
356	K	33.4	Very low	46.8	Very low	200 Å²	200	138 Å²	138	87%	0.87	69%	0.688	S	S	*	*			trans	-63.3	97.8	175.2	-77.8	178.4	179.2	172.5	0	103.4	K354 R358	K354-K356 PolarHBondContact O-N 3.1Å; K356-R358 PolarHBondContact O-N 3.44Å
357	I	41.6	Very low	48.9	Very low	151 Å²	151	133.5 Å²	133.5	77%	0.774	66%	0.659	S	S	*	*			trans	-62.3	85.2	169.9	-59.8	171.1	0	0	0	103.8	A355 K359	A355-I357 PolarHBondContact O-N 3.31Å; I357-K359 PolarHBondContact O-N 3.3Å
358	R	35.8	Very low	51	Low	231 Å²	231	127.8 Å²	127.8	87%	0.872	64%	0.642	S	S	*	*			trans	-56.9	100.7	152	-94.1	-173.8	165.8	-173.6	-2.9	102	K356 S360	K356-R358 PolarHBondContact O-N 3.44Å; R358-S360 PolarHBondContact O-N 3.16Å
359	K	43.1	Very low	53.2	Low	158 Å²	158	127.9 Å²	127.9	69%	0.687	64%	0.639	S	S	*	*			trans	-53.9	90	156.3	-91.5	-174.4	166.1	-172.7	0	105.3	I357 W361	I357-K359 PolarHBondContact O-N 3.3Å; K359-W361 VanDerWaalsContact C-N 3.28Å; K359-W361 PolarHBondContact O-N 2.99Å
360	S	48.3	Very low	55.4	Low	112 Å²	112	122.3 Å²	122.3	78%	0.783	62%	0.621	S	S	*	*			trans	-65	103.6	165.3	-165.2	0	0	0	0	103.3	R358	R358-S360 PolarHBondContact O-N 3.16Å
361	W	56.1	Low	57.7	Low	122 Å²	122	114.4 Å²	114.4	46%	0.462	59%	0.586	S	S	.	*	P	Polyproline II helix	trans	-58.9	130.5	178.6	-70.3	94.4	0	0	0	107.1	R158 K359 G363	R158-W361 HydrophobicContact CB-CZ3 4.4Å; R158-W361 HydrophobicContact CG-CZ3 4.3Å; K359-W361 VanDerWaalsContact C-N 3.28Å; K359-W361 PolarHBondContact O-N 2.99Å; W361-G363 PolarHBondContact O-N 3.23Å
362	P	64.5	Low	60	Low	78 Å²	78	115.3 Å²	115.3	51%	0.506	58%	0.582	S	S	.	*	P	Polyproline II helix	trans	-53.4	142.4	177.3	22.3	-32.7	0	0	0	109.1
363	G	72.8	Confident	62.5	Low	30 Å²	30	116.7 Å²	116.7	31%	0.309	58%	0.577	S	S	.	*	P	Polyproline II helix	trans	-59.3	145.3	179.7	0	0	0	0	0	109.8	W361 R365 D366 M367	W361-G363 PolarHBondContact O-N 3.23Å; G363-R365 PolarHBondContact O-N 2.99Å; G363-D366 WeakPolarHBondContact CA-OD2 3.38Å; G363-D366 PolarHBondContact N-OD2 3.01Å; G363-D366 PolarHBondContact O-N 3.02Å; G363-M367 PolarHBondContact O-N 2.88Å
364	V	75.3	Confident	65.1	Low	92 Å²	92	111 Å²	111	56%	0.558	54%	0.54	S	S	*	.	H	α-helix	trans	-55.6	-28.6	174.8	174.9	0	0	0	0	111	M367 I368	V364-M367 HydrophobicContact CG1-CE 4.08Å; V364-I368 HydrophobicContact CG1-CD1 3.94Å; V364-I368 WeakPolarHBondContact O-CB 3.48Å; V364-I368 WeakPolarHBondContact O-CD1 3.45Å; V364-I368 WeakPolarHBondContact O-CG1 3.34Å; V364-I368 PolarHBondContact O-N 3.39Å; V364-I368 VanDerWaalsContact O-N 3.15Å
365	R	77.8	Confident	67.9	Low	218 Å²	218	102.9 Å²	102.9	82%	0.823	51%	0.509	S	S	*	.	H	α-helix	trans	-67.1	-43.6	173.9	-54.3	-174.5	84.2	-176.5	5.7	112	G363 I368 L369	G363-R365 PolarHBondContact O-N 2.99Å; R365-I368 PolarHBondContact O-N 3.46Å; R365-L369 VanDerWaalsContact O-CB 3.3Å; R365-L369 WeakPolarHBondContact O-CB 3.42Å; R365-L369 PolarHBondContact O-N 2.97Å
366	D	77.7	Confident	70.6	Confident	96 Å²	96	106.9 Å²	106.9	51%	0.513	51%	0.506	S	S	.	.	H	α-helix	trans	-70	-42.1	-177.7	-41.8	-38.2	0	0	0	110.5	G363 I368 L369 H370	G363-D366 WeakPolarHBondContact CA-OD2 3.38Å; G363-D366 PolarHBondContact N-OD2 3.01Å; G363-D366 PolarHBondContact O-N 3.02Å; D366-I368 PolarHBondContact O-N 3.5Å; D366-L369 PolarHBondContact O-N 3.02Å; D366-H370 WeakPolarHBondContact O-CB 3.39Å; D366-H370 PolarHBondContact O-N 2.62Å
367	M	75.1	Confident	73.5	Confident	23 Å²	23	101.2 Å²	101.2	11%	0.113	49%	0.488	C	S	.	.	H	α-helix	trans	-52.1	-51.6	169.2	165.8	168.2	88.1	0	0	111.9	V154 E157 G363 V364 L369 R371	V154-M367 HydrophobicContact CG2-CE 4.34Å; E157-M367 VanDerWaalsContact OE1-CG 3.32Å; E157-M367 WeakPolarHBondContact OE1-CG 3.33Å; E157-M367 VanDerWaalsContact OE2-CB 3.23Å; E157-M367 WeakPolarHBondContact OE2-CB 3.33Å; E157-M367 WeakPolarHBondContact OE2-CG 3.48Å; G363-M367 PolarHBondContact O-N 2.88Å; V364-M367 HydrophobicContact CG1-CE 4.08Å; M367-L369 VanDerWaalsContact C-N 3.35Å; M367-R371 WeakPolarHBondContact O-CG 3.48Å; M367-R371 PolarHBondContact O-N 2.9Å; M367-R371 VanDerWaalsContact O-N 3.14Å
368	I	80.9	Confident	76	Confident	102 Å²	102	94 Å²	94	52%	0.523	45%	0.451	S	S	.	.	H	α-helix	trans	-66.2	-39.2	179.7	-70	167.1	0	0	0	110.7	V364 R365 D366 R371 Y372	V364-I368 HydrophobicContact CG1-CD1 3.94Å; V364-I368 WeakPolarHBondContact O-CB 3.48Å; V364-I368 WeakPolarHBondContact O-CD1 3.45Å; V364-I368 WeakPolarHBondContact O-CG1 3.34Å; V364-I368 PolarHBondContact O-N 3.39Å; V364-I368 VanDerWaalsContact O-N 3.15Å; R365-I368 PolarHBondContact O-N 3.46Å; D366-I368 PolarHBondContact O-N 3.5Å; I368-R371 PolarHBondContact O-N 2.97Å; I368-Y372 VanDerWaalsContact O-CB 3.28Å; I368-Y372 WeakPolarHBondContact O-CB 3.22Å; I368-Y372 PolarHBondContact O-N 3.4Å
369	L	83.5	Confident	78.8	Confident	103 Å²	103	90.3 Å²	90.3	54%	0.539	44%	0.437	S	S	.	.	H	α-helix	trans	-66.4	-42.9	-179.4	-170	140.3	0	0	0	111.7	R365 D366 M367 Y372 M373	R365-L369 VanDerWaalsContact O-CB 3.3Å; R365-L369 WeakPolarHBondContact O-CB 3.42Å; R365-L369 PolarHBondContact O-N 2.97Å; D366-L369 PolarHBondContact O-N 3.02Å; M367-L369 VanDerWaalsContact C-N 3.35Å; L369-Y372 WeakPolarHBondContact O-CB 3.31Å; L369-Y372 PolarHBondContact O-N 3.35Å; L369-M373 HydrophobicContact CD2-CG 4.4Å; L369-M373 HydrophobicContact CD2-SD 3.78Å; L369-M373 WeakPolarHBondContact O-CG 3.38Å; L369-M373 PolarHBondContact O-N 2.83Å
370	H	80.1	Confident	81.4	Confident	78 Å²	78	83.1 Å²	83.1	36%	0.361	41%	0.408	S	S	.	.	H	α-helix	trans	-65	-41	175.9	-167.4	-105.2	0	0	0	111.9	D366 Y372 M373 V374 Q504 L507	D366-H370 WeakPolarHBondContact O-CB 3.39Å; D366-H370 PolarHBondContact O-N 2.62Å; H370-Y372 PolarHBondContact O-N 2.76Å; H370-M373 PolarHBondContact O-N 3.29Å; H370-V374 PolarHBondContact O-N 2.83Å; H370-V374 VanDerWaalsContact O-N 3.12Å; H370-Q504 PolarHBondContact NE2-NE2 3.23Å; H370-L507 WeakPolarHBondContact ND1-CD2 3.4Å
371	R	84.5	Confident	83.6	Confident	18 Å²	18	78.6 Å²	78.6	7%	0.068	37%	0.374	C	S	.	.	H	α-helix	trans	-61.7	-40.8	171.1	-75.3	172.4	-174.1	-86.6	-14	112.6	N153 E157 M367 I368 V374 S375 L507	N153-R371 PolarHBondContact O-NH2 3.06Å; N153-R371 VanDerWaalsContact O-NH2 3.13Å; N153-R371 PolarHBondContact OD1-NH1 2.94Å; E157-R371 IonicContact OE1-CZ 3.5Å; E157-R371 VanDerWaalsContact OE1-CZ 3.22Å; E157-R371 IonicContact OE1-NE 2.7Å; E157-R371 PolarHBondContact OE1-NE 3.13Å; E157-R371 IonicContact OE1-NH2 3.42Å; E157-R371 PolarHBondContact OE1-NH2 3.39Å; M367-R371 WeakPolarHBondContact O-CG 3.48Å; M367-R371 PolarHBondContact O-N 2.9Å; M367-R371 VanDerWaalsContact O-N 3.14Å; I368-R371 PolarHBondContact O-N 2.97Å; R371-V374 PolarHBondContact O-N 3.24Å; R371-S375 VanDerWaalsContact O-CB 3.32Å; R371-S375 WeakPolarHBondContact O-CB 3.49Å; R371-S375 PolarHBondContact O-N 3.39Å; R371-S375 PolarHBondContact O-OG 3.24Å; R371-L507 HydrophobicContact CG-CD1 3.78Å; R371-L507 HydrophobicContact CG-CD2 3.89Å; R371-L507 HydrophobicContact CG-CG 4.16Å; R371-L507 VanDerWaalsContact CZ-CD1 3.42Å
372	Y	87.1	Confident	85.5	Confident	134 Å²	134	74.2 Å²	74.2	53%	0.525	36%	0.359	S	S	.	.	H	α-helix	trans	-65.4	-41.8	177.4	175.8	-104.8	0	0	0	112	I368 L369 H370 S375 R376	I368-Y372 VanDerWaalsContact O-CB 3.28Å; I368-Y372 WeakPolarHBondContact O-CB 3.22Å; I368-Y372 PolarHBondContact O-N 3.4Å; L369-Y372 WeakPolarHBondContact O-CB 3.31Å; L369-Y372 PolarHBondContact O-N 3.35Å; H370-Y372 PolarHBondContact O-N 2.76Å; Y372-S375 PolarHBondContact O-N 3.43Å; Y372-R376 VanDerWaalsContact CE1-CD 3.48Å; Y372-R376 HydrophobicContact CE1-CG 4.18Å; Y372-R376 HydrophobicContact CE2-CG 4.21Å; Y372-R376 WeakPolarHBondContact O-CG 3.49Å; Y372-R376 PolarHBondContact O-N 3.42Å
373	M	88.5	Confident	87	Confident	101 Å²	101	74.3 Å²	74.3	50%	0.498	35%	0.354	S	S	.	.	H	α-helix	trans	-59.8	-49.5	174.6	-72.7	178.3	70.6	0	0	111.8	L369 H370 S375 R376 V377	L369-M373 HydrophobicContact CD2-CG 4.4Å; L369-M373 HydrophobicContact CD2-SD 3.78Å; L369-M373 WeakPolarHBondContact O-CG 3.38Å; L369-M373 PolarHBondContact O-N 2.83Å; H370-M373 PolarHBondContact O-N 3.29Å; M373-S375 PolarHBondContact O-N 2.94Å; M373-R376 PolarHBondContact O-N 2.89Å; M373-V377 PolarHBondContact O-N 2.71Å
374	V	90.7	Very high	88.2	Confident	0 Å²	0	72.9 Å²	72.9	0%	0	34%	0.339	C	S	.	.	H	α-helix	trans	-58.4	-49.5	174.6	169.3	0	0	0	0	110.7	H370 R371 R376 V377 I378 V500 Q504 L507 A508	H370-V374 PolarHBondContact O-N 2.83Å; H370-V374 VanDerWaalsContact O-N 3.12Å; R371-V374 PolarHBondContact O-N 3.24Å; V374-R376 VanDerWaalsContact C-N 3.27Å; V374-R376 PolarHBondContact O-N 3.48Å; V374-V377 PolarHBondContact O-N 3.21Å; V374-I378 HydrophobicContact CG1-CD1 4.11Å; V374-I378 HydrophobicContact CG1-CG1 4.5Å; V374-I378 WeakPolarHBondContact O-CG1 3.41Å; V374-I378 PolarHBondContact O-N 3.5Å; V374-V500 HydrophobicContact CG1-CG1 4.4Å; V374-Q504 HydrophobicContact CG2-CB 3.99Å; V374-Q504 HydrophobicContact CG2-CG 4.3Å; V374-L507 HydrophobicContact CG2-CD2 4.09Å; V374-L507 HydrophobicContact CG2-CG 4.47Å; V374-A508 HydrophobicContact CG1-CB 3.95Å
375	S	92	Very high	89.2	Confident	31 Å²	31	68.5 Å²	68.5	22%	0.217	31%	0.313	C	S	.	.	H	α-helix	trans	-57.1	-38.4	-179.9	-58	0	0	0	0	112.6	R371 Y372 M373 V377 I378 W379 T511	R371-S375 VanDerWaalsContact O-CB 3.32Å; R371-S375 WeakPolarHBondContact O-CB 3.49Å; R371-S375 PolarHBondContact O-N 3.39Å; R371-S375 PolarHBondContact O-OG 3.24Å; Y372-S375 PolarHBondContact O-N 3.43Å; M373-S375 PolarHBondContact O-N 2.94Å; S375-V377 VanDerWaalsContact C-N 3.27Å; S375-V377 PolarHBondContact O-N 2.9Å; S375-I378 PolarHBondContact O-N 3.39Å; S375-W379 WeakPolarHBondContact O-CA 2.92Å; S375-W379 WeakPolarHBondContact O-CB 3.12Å; S375-W379 PolarHBondContact O-N 3.49Å; S375-T511 WeakPolarHBondContact OG-CG2 3.39Å
376	R	93.5	Very high	90	Very high	167 Å²	167	58.7 Å²	58.7	63%	0.63	28%	0.279	S	S	*	.	H	α-helix	trans	-63.8	-27.8	176.3	-81.2	-173.1	66	174.4	-0.3	113.8	Y372 M373 V374	Y372-R376 VanDerWaalsContact CE1-CD 3.48Å; Y372-R376 HydrophobicContact CE1-CG 4.18Å; Y372-R376 HydrophobicContact CE2-CG 4.21Å; Y372-R376 WeakPolarHBondContact O-CG 3.49Å; Y372-R376 PolarHBondContact O-N 3.42Å; M373-R376 PolarHBondContact O-N 2.89Å; V374-R376 VanDerWaalsContact C-N 3.27Å; V374-R376 PolarHBondContact O-N 3.48Å
377	V	93.8	Very high	90.9	Very high	81 Å²	81	55.7 Å²	55.7	49%	0.491	26%	0.264	S	S	.	.	H	α-helix	trans	-80.2	-40.4	177.2	178.8	0	0	0	0	111	M373 V374 S375 K499 V500	M373-V377 PolarHBondContact O-N 2.71Å; V374-V377 PolarHBondContact O-N 3.21Å; S375-V377 VanDerWaalsContact C-N 3.27Å; S375-V377 PolarHBondContact O-N 2.9Å; V377-K499 HydrophobicContact CG1-CB 4.36Å; V377-K499 WeakPolarHBondContact CG1-O 3.38Å; V377-V500 HydrophobicContact CG1-CG1 4.35Å
378	I	95	Very high	92	Very high	0 Å²	0	54.6 Å²	54.6	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-101.8	8.8	-173.4	66.2	173.2	0	0	0	114.9	V374 S375 A380 Y381 M382 A496 K499 V500 A508 M512	V374-I378 HydrophobicContact CG1-CD1 4.11Å; V374-I378 HydrophobicContact CG1-CG1 4.5Å; V374-I378 WeakPolarHBondContact O-CG1 3.41Å; V374-I378 PolarHBondContact O-N 3.5Å; S375-I378 PolarHBondContact O-N 3.39Å; I378-A380 VanDerWaalsContact C-N 3.27Å; I378-A380 PolarHBondContact O-N 3.27Å; I378-A380 VanDerWaalsContact O-N 3.07Å; I378-Y381 HydrophobicContact CB-CD2 4.35Å; I378-Y381 WeakPolarHBondContact O-CA 3.42Å; I378-Y381 WeakPolarHBondContact O-CB 3.1Å; I378-Y381 PolarHBondContact O-N 3.45Å; I378-M382 HydrophobicContact CD1-CG 4.1Å; I378-M382 HydrophobicContact CD1-SD 4.15Å; I378-M382 HydrophobicContact CG1-CG 3.93Å; I378-M382 HydrophobicContact CG1-SD 3.81Å; I378-M382 PolarHBondContact O-N 2.92Å; I378-A496 HydrophobicContact CB-CB 4.39Å; I378-A496 HydrophobicContact CD1-CB 4.4Å; I378-A496 HydrophobicContact CG2-CB 4.26Å; I378-K499 HydrophobicContact CG2-CB 4.23Å; I378-V500 HydrophobicContact CG2-CG1 4.05Å; I378-A508 HydrophobicContact CD1-CB 4.14Å; I378-M512 HydrophobicContact CD1-CG 3.92Å; I378-M512 HydrophobicContact CD1-SD 4.03Å
379	W	95.4	Very high	92.7	Very high	152 Å²	152	50.3 Å²	50.3	58%	0.576	24%	0.236	S	C	*	.	H	α-helix	trans	-49.3	-41	-171	75.3	-88.3	0	0	0	114.6	S375 M382 L383 L443	S375-W379 WeakPolarHBondContact O-CA 2.92Å; S375-W379 WeakPolarHBondContact O-CB 3.12Å; S375-W379 PolarHBondContact O-N 3.49Å; W379-M382 WeakPolarHBondContact O-CB 3.41Å; W379-M382 PolarHBondContact O-N 3.41Å; W379-L383 HydrophobicContact CZ3-CD2 4.42Å; W379-L383 WeakPolarHBondContact O-CB 3.23Å; W379-L383 PolarHBondContact O-N 3.32Å; W379-L443 HydrophobicContact CH2-CD2 4.34Å; W379-L443 HydrophobicContact CZ3-CD2 3.97Å
380	A	96	Very high	93.2	Very high	8 Å²	8	46.5 Å²	46.5	7%	0.066	22%	0.218	C	C	.	.	H	α-helix	trans	-70	-34	-178.3	0	0	0	0	0	112.1	I378 S384	I378-A380 VanDerWaalsContact C-N 3.27Å; I378-A380 PolarHBondContact O-N 3.27Å; I378-A380 VanDerWaalsContact O-N 3.07Å; A380-S384 WeakPolarHBondContact O-CB 3.32Å; A380-S384 PolarHBondContact O-N 3.14Å
381	Y	96.1	Very high	93.9	Very high	17 Å²	17	43.5 Å²	43.5	7%	0.067	20%	0.204	C	C	.	.	H	α-helix	trans	-71.3	-41.9	173.9	-57.3	-83.3	0	0	0	110.7	I378 S384 I385 W437 G439 L442 P492 Q495 K499	I378-Y381 HydrophobicContact CB-CD2 4.35Å; I378-Y381 WeakPolarHBondContact O-CA 3.42Å; I378-Y381 WeakPolarHBondContact O-CB 3.1Å; I378-Y381 PolarHBondContact O-N 3.45Å; Y381-S384 PolarHBondContact O-N 3.1Å; Y381-I385 WeakPolarHBondContact O-CG2 3.33Å; Y381-I385 PolarHBondContact O-N 2.85Å; Y381-I385 VanDerWaalsContact O-N 3.07Å; Y381-W437 PolarHBondContact OH-O 3.29Å; Y381-G439 PolarHBondContact OH-N 2.87Å; Y381-L442 HydrophobicContact CD1-CD1 3.62Å; Y381-L442 HydrophobicContact CE1-CD1 3.58Å; Y381-P492 HydrophobicContact CD1-CB 4.22Å; Y381-Q495 HydrophobicContact CE1-CB 4.15Å; Y381-K499 HydrophobicContact CE2-CG 4.04Å; Y381-K499 VanDerWaalsContact OH-CE 3.28Å; Y381-K499 WeakPolarHBondContact OH-CE 3.47Å
382	M	95.8	Very high	94.4	Very high	30 Å²	30	42.8 Å²	42.8	15%	0.148	20%	0.202	C	C	.	.	H	α-helix	trans	-58.9	-47.4	174.2	-72	178.1	68.8	0	0	112.1	I378 W379 I385 A386 T511 M512 S515	I378-M382 HydrophobicContact CD1-CG 4.1Å; I378-M382 HydrophobicContact CD1-SD 4.15Å; I378-M382 HydrophobicContact CG1-CG 3.93Å; I378-M382 HydrophobicContact CG1-SD 3.81Å; I378-M382 PolarHBondContact O-N 2.92Å; W379-M382 WeakPolarHBondContact O-CB 3.41Å; W379-M382 PolarHBondContact O-N 3.41Å; M382-I385 VanDerWaalsContact O-CG2 3.24Å; M382-I385 WeakPolarHBondContact O-CG2 3.43Å; M382-A386 WeakPolarHBondContact O-CB 3.18Å; M382-A386 PolarHBondContact O-N 3.26Å; M382-A386 VanDerWaalsContact O-N 3.12Å; M382-T511 HydrophobicContact CE-CG2 3.57Å; M382-T511 HydrophobicContact SD-CG2 3.78Å; M382-M512 HydrophobicContact CB-SD 4.27Å; M382-M512 HydrophobicContact CG-SD 3.53Å; M382-M512 VanDerWaalsContact CG-SD 3.53Å; M382-S515 VanDerWaalsContact C-OG 3.25Å; M382-S515 WeakPolarHBondContact CB-OG 3.49Å; M382-S515 PolarHBondContact O-OG 2.97Å
383	L	96.4	Very high	94.5	Very high	79 Å²	79	38.3 Å²	38.3	41%	0.414	19%	0.187	S	C	.	.	H	α-helix	trans	-70.9	-37.8	-179.6	-171.1	61.4	0	0	0	111.7	W379 A386 V387 L443	W379-L383 HydrophobicContact CZ3-CD2 4.42Å; W379-L383 WeakPolarHBondContact O-CB 3.23Å; W379-L383 PolarHBondContact O-N 3.32Å; L383-A386 PolarHBondContact O-N 3.48Å; L383-V387 HydrophobicContact CD1-CG2 4.06Å; L383-V387 HydrophobicContact CG-CG2 4.23Å; L383-V387 WeakPolarHBondContact O-CB 3.33Å; L383-V387 VanDerWaalsContact O-CG2 3.29Å; L383-V387 WeakPolarHBondContact O-CG2 3.42Å; L383-V387 PolarHBondContact O-N 3.24Å; L383-L443 HydrophobicContact CB-CD1 4.04Å; L383-L443 HydrophobicContact CD2-CD1 3.82Å; L383-L443 HydrophobicContact CD2-CD2 3.91Å; L383-L443 HydrophobicContact CG-CD1 3.66Å
384	S	96.8	Very high	94.6	Very high	0 Å²	0	34.5 Å²	34.5	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-58.1	-48.9	175.1	167.4	0	0	0	0	112.4	A380 Y381 T388 S446 P492	A380-S384 WeakPolarHBondContact O-CB 3.32Å; A380-S384 PolarHBondContact O-N 3.14Å; Y381-S384 PolarHBondContact O-N 3.1Å; S384-T388 VanDerWaalsContact O-CB 3.31Å; S384-T388 WeakPolarHBondContact O-CB 3.2Å; S384-T388 PolarHBondContact O-N 2.67Å; S384-T388 PolarHBondContact O-OG1 2.92Å; S384-S446 WeakPolarHBondContact O-CB 3.27Å; S384-S446 PolarHBondContact O-OG 3.44Å; S384-S446 PolarHBondContact OG-OG 3.08Å; S384-P492 WeakPolarHBondContact OG-CG 3.31Å
385	I	95.8	Very high	94.5	Very high	0 Å²	0	34.5 Å²	34.5	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-67.7	-40.7	178.2	-166.6	166.9	0	0	0	111.6	Y381 M382 T388 Y389 G489 P492 M493 M512 Y516	Y381-I385 WeakPolarHBondContact O-CG2 3.33Å; Y381-I385 PolarHBondContact O-N 2.85Å; Y381-I385 VanDerWaalsContact O-N 3.07Å; M382-I385 VanDerWaalsContact O-CG2 3.24Å; M382-I385 WeakPolarHBondContact O-CG2 3.43Å; I385-T388 PolarHBondContact O-N 3.48Å; I385-Y389 HydrophobicContact CD1-CD2 4.5Å; I385-Y389 HydrophobicContact CD1-CE2 4.15Å; I385-Y389 HydrophobicContact CG1-CD2 3.67Å; I385-Y389 HydrophobicContact CG1-CE2 3.73Å; I385-Y389 WeakPolarHBondContact O-CD2 3.49Å; I385-Y389 PolarHBondContact O-N 3.38Å; I385-Y389 VanDerWaalsContact O-N 3.1Å; I385-G489 VanDerWaalsContact CD1-O 3.26Å; I385-G489 WeakPolarHBondContact CD1-O 3.2Å; I385-P492 HydrophobicContact CB-CB 4.37Å; I385-M493 HydrophobicContact CD1-CB 4.23Å; I385-M493 HydrophobicContact CD1-CE 3.98Å; I385-M512 HydrophobicContact CB-CE 4.39Å; I385-M512 HydrophobicContact CG2-CE 3.79Å; I385-Y516 HydrophobicContact CD1-CD2 4.45Å; I385-Y516 HydrophobicContact CD1-CG 4.43Å; I385-Y516 HydrophobicContact CG1-CD2 4.42Å
386	A	96.2	Very high	94.2	Very high	13 Å²	13	34.5 Å²	34.5	11%	0.107	17%	0.166	C	C	.	.	H	α-helix	trans	-62.4	-47.4	179	0	0	0	0	0	112.2	M382 L383 S390 S515 G519	M382-A386 WeakPolarHBondContact O-CB 3.18Å; M382-A386 PolarHBondContact O-N 3.26Å; M382-A386 VanDerWaalsContact O-N 3.12Å; L383-A386 PolarHBondContact O-N 3.48Å; A386-S390 WeakPolarHBondContact O-CB 2.92Å; A386-S390 PolarHBondContact O-N 3.49Å; A386-S515 WeakPolarHBondContact CB-O 3.33Å; A386-G519 VanDerWaalsContact O-CA 3.23Å; A386-G519 WeakPolarHBondContact O-CA 3.36Å
387	V	96.8	Very high	93.2	Very high	32 Å²	32	29.7 Å²	29.7	19%	0.194	16%	0.157	C	C	.	.	H	α-helix	trans	-64.5	-42.7	177.3	170.8	0	0	0	0	111.1	L383 Y389 S390 I391	L383-V387 HydrophobicContact CD1-CG2 4.06Å; L383-V387 HydrophobicContact CG-CG2 4.23Å; L383-V387 WeakPolarHBondContact O-CB 3.33Å; L383-V387 VanDerWaalsContact O-CG2 3.29Å; L383-V387 WeakPolarHBondContact O-CG2 3.42Å; L383-V387 PolarHBondContact O-N 3.24Å; V387-Y389 PolarHBondContact O-N 2.89Å; V387-S390 PolarHBondContact O-N 3.01Å; V387-I391 HydrophobicContact CG1-CD1 3.58Å; V387-I391 HydrophobicContact CG1-CG1 4.39Å; V387-I391 WeakPolarHBondContact O-CG1 3.28Å; V387-I391 PolarHBondContact O-N 3.23Å
388	T	96.8	Very high	92.4	Very high	0 Å²	0	27.5 Å²	27.5	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-55.9	-54.4	178.6	-66.4	0	0	0	0	111.5	S384 I385 I391 T392 S446 F488	S384-T388 VanDerWaalsContact O-CB 3.31Å; S384-T388 WeakPolarHBondContact O-CB 3.2Å; S384-T388 PolarHBondContact O-N 2.67Å; S384-T388 PolarHBondContact O-OG1 2.92Å; I385-T388 PolarHBondContact O-N 3.48Å; T388-I391 PolarHBondContact O-N 2.94Å; T388-T392 PolarHBondContact O-N 3.07Å; T388-T392 VanDerWaalsContact O-N 3.09Å; T388-T392 PolarHBondContact O-OG1 2.91Å; T388-S446 VanDerWaalsContact OG1-CB 3.32Å; T388-S446 WeakPolarHBondContact OG1-CB 3.39Å; T388-S446 PolarHBondContact OG1-OG 3.27Å; T388-S446 VanDerWaalsContact OG1-OG 3.12Å; T388-F488 HydrophobicContact CG2-CB 4.31Å
389	Y	95.1	Very high	91.7	Very high	12 Å²	12	29.8 Å²	29.8	5%	0.047	16%	0.162	C	C	.	.	H	α-helix	trans	-74.9	-27.4	-178.9	-79	-77.2	0	0	0	113.7	I385 V387 T392 L393 Y516 L520	I385-Y389 HydrophobicContact CD1-CD2 4.5Å; I385-Y389 HydrophobicContact CD1-CE2 4.15Å; I385-Y389 HydrophobicContact CG1-CD2 3.67Å; I385-Y389 HydrophobicContact CG1-CE2 3.73Å; I385-Y389 WeakPolarHBondContact O-CD2 3.49Å; I385-Y389 PolarHBondContact O-N 3.38Å; I385-Y389 VanDerWaalsContact O-N 3.1Å; V387-Y389 PolarHBondContact O-N 2.89Å; Y389-T392 PolarHBondContact O-N 3.36Å; Y389-L393 PolarHBondContact O-N 3.38Å; Y389-Y516 HydrophobicContact CD1-CD2 4.31Å; Y389-Y516 AromaticContact CD1-CE2 3.68Å; Y389-Y516 HydrophobicContact CD1-CE2 3.68Å; Y389-Y516 AromaticContact CD2-CD2 3.4Å; Y389-Y516 HydrophobicContact CD2-CD2 3.4Å; Y389-Y516 VanDerWaalsContact CD2-CD2 3.4Å; Y389-Y516 AromaticContact CD2-CE2 3.57Å; Y389-Y516 HydrophobicContact CD2-CE2 3.57Å; Y389-Y516 HydrophobicContact CE1-CD2 4.45Å; Y389-Y516 AromaticContact CE1-CE2 3.62Å; Y389-Y516 HydrophobicContact CE1-CE2 3.62Å; Y389-Y516 AromaticContact CE2-CD2 3.57Å; Y389-Y516 HydrophobicContact CE2-CD2 3.57Å; Y389-Y516 AromaticContact CE2-CE2 3.49Å; Y389-Y516 HydrophobicContact CE2-CE2 3.49Å; Y389-Y516 VanDerWaalsContact CE2-CE2 3.49Å; Y389-Y516 AromaticContact CG-CD2 3.78Å; Y389-Y516 HydrophobicContact CG-CD2 3.78Å; Y389-Y516 AromaticContact CG-CE2 3.64Å; Y389-Y516 HydrophobicContact CG-CE2 3.64Å; Y389-Y516 AromaticContact CZ-CE2 3.51Å; Y389-L520 HydrophobicContact CD1-CD2 3.76Å; Y389-L520 HydrophobicContact CG-CD2 4.11Å
390	S	95	Very high	91.1	Very high	23 Å²	23	22.5 Å²	22.5	16%	0.161	14%	0.135	C	C	.	.	H	α-helix	trans	-66	-41.9	172.3	-178.7	0	0	0	0	112.1	A386 V387 C394 G519 V522 G523	A386-S390 WeakPolarHBondContact O-CB 2.92Å; A386-S390 PolarHBondContact O-N 3.49Å; V387-S390 PolarHBondContact O-N 3.01Å; S390-C394 WeakPolarHBondContact O-CB 3.26Å; S390-C394 PolarHBondContact O-N 3.4Å; S390-C394 VanDerWaalsContact O-N 3.11Å; S390-G519 WeakPolarHBondContact CA-O 3.1Å; S390-G519 WeakPolarHBondContact CB-O 3.32Å; S390-G519 PolarHBondContact N-O 3.05Å; S390-V522 WeakPolarHBondContact OG-CG1 3.39Å; S390-G523 WeakPolarHBondContact O-CA 3.47Å; S390-G523 PolarHBondContact OG-N 3.41Å
391	I	95	Very high	90.3	Very high	16 Å²	16	24.2 Å²	24.2	8%	0.082	15%	0.146	C	C	.	.	H	α-helix	trans	-68.6	-41.6	176.1	-67.1	164.4	0	0	0	109.8	V387 T388 C394 L395 R449 V450 I453	V387-I391 HydrophobicContact CG1-CD1 3.58Å; V387-I391 HydrophobicContact CG1-CG1 4.39Å; V387-I391 WeakPolarHBondContact O-CG1 3.28Å; V387-I391 PolarHBondContact O-N 3.23Å; T388-I391 PolarHBondContact O-N 2.94Å; I391-C394 WeakPolarHBondContact O-CB 3.17Å; I391-C394 PolarHBondContact O-N 3.02Å; I391-L395 HydrophobicContact CG2-CD1 4.35Å; I391-R449 HydrophobicContact CB-CB 4.48Å; I391-R449 HydrophobicContact CD1-CB 3.88Å; I391-R449 HydrophobicContact CG2-CB 4.03Å; I391-V450 HydrophobicContact CD1-CB 4.24Å; I391-I453 HydrophobicContact CG2-CG1 4.41Å
392	T	94.8	Very high	89.4	Confident	3 Å²	3	27.5 Å²	27.5	2%	0.018	16%	0.162	C	C	.	.	H	α-helix	trans	-60.7	-51.9	176.7	-59.2	0	0	0	0	112	T388 Y389 C394 L395 F396 F420 R449 N485	T388-T392 PolarHBondContact O-N 3.07Å; T388-T392 VanDerWaalsContact O-N 3.09Å; T388-T392 PolarHBondContact O-OG1 2.91Å; Y389-T392 PolarHBondContact O-N 3.36Å; T392-C394 PolarHBondContact O-N 2.91Å; T392-L395 PolarHBondContact O-N 3.04Å; T392-F396 HydrophobicContact CG2-CB 4.42Å; T392-F396 PolarHBondContact O-N 3.04Å; T392-F420 HydrophobicContact CG2-CE1 4.47Å; T392-F420 HydrophobicContact CG2-CE2 3.91Å; T392-F420 HydrophobicContact CG2-CZ 3.52Å; T392-R449 PolarHBondContact OG1-NH2 3.31Å; T392-N485 WeakPolarHBondContact CB-OD1 3.38Å; T392-N485 PolarHBondContact OG1-OD1 3.39Å
393	L	90.3	Very high	88.6	Confident	39 Å²	39	26.4 Å²	26.4	20%	0.204	16%	0.157	C	C	.	.	H	α-helix	trans	-73.7	-9.9	179.4	-71.8	-155.4	0	0	0	114.8	Y389 F396 L520 S524	Y389-L393 PolarHBondContact O-N 3.38Å; L393-F396 WeakPolarHBondContact CA-O 3.22Å; L393-F396 HydrophobicContact CD2-CD1 4.48Å; L393-F396 VanDerWaalsContact CD2-O 3.27Å; L393-F396 WeakPolarHBondContact CD2-O 3.27Å; L393-L520 HydrophobicContact CD1-CB 3.84Å; L393-L520 HydrophobicContact CD1-CD2 3.5Å; L393-L520 VanDerWaalsContact CD1-CD2 3.5Å; L393-L520 HydrophobicContact CD1-CG 4.25Å; L393-L520 HydrophobicContact CG-CD2 3.77Å; L393-S524 WeakPolarHBondContact CD1-OG 3.49Å
394	C	89.2	Confident	87.7	Confident	21 Å²	21	30.8 Å²	30.8	14%	0.142	17%	0.168	C	C	.	.	H	α-helix	trans	-69.6	-22.8	165.5	-171.4	0	0	0	0	112.2	S390 I391 T392	S390-C394 WeakPolarHBondContact O-CB 3.26Å; S390-C394 PolarHBondContact O-N 3.4Å; S390-C394 VanDerWaalsContact O-N 3.11Å; I391-C394 WeakPolarHBondContact O-CB 3.17Å; I391-C394 PolarHBondContact O-N 3.02Å; T392-C394 PolarHBondContact O-N 2.91Å
395	L	88.9	Confident	87	Confident	1 Å²	1	32.7 Å²	32.7	1%	0.005	18%	0.178	C	C	.	.	H	α-helix	trans	-117.4	-48.3	-169.9	-61.2	170.5	0	0	0	112.4	I391 T392 G398 L399 E400 F452 I453 F456 M481	I391-L395 HydrophobicContact CG2-CD1 4.35Å; T392-L395 PolarHBondContact O-N 3.04Å; L395-G398 PolarHBondContact O-N 2.81Å; L395-L399 HydrophobicContact CD2-CD2 3.64Å; L395-L399 WeakPolarHBondContact O-CB 3.3Å; L395-L399 PolarHBondContact O-N 3.28Å; L395-E400 PolarHBondContact O-N 2.99Å; L395-E400 VanDerWaalsContact O-N 3.12Å; L395-F452 HydrophobicContact CD1-CB 3.74Å; L395-I453 HydrophobicContact CD1-CG1 4.05Å; L395-I453 HydrophobicContact CD2-CB 4.43Å; L395-I453 HydrophobicContact CD2-CG1 4.16Å; L395-I453 HydrophobicContact CG-CG1 4.33Å; L395-F456 HydrophobicContact CD1-CD2 3.95Å; L395-F456 HydrophobicContact CD1-CE2 4.38Å; L395-F456 HydrophobicContact CD2-CB 4.28Å; L395-F456 HydrophobicContact CD2-CD2 4.38Å; L395-M481 HydrophobicContact CB-CE 4.34Å; L395-M481 HydrophobicContact CB-SD 4.05Å; L395-M481 HydrophobicContact CD1-SD 3.68Å
396	F	85.3	Confident	85.9	Confident	30 Å²	30	43.1 Å²	43.1	13%	0.132	22%	0.223	C	C	.	.	T	Hydrogen-bonded Turn	trans	-103.5	135.6	179.9	172.3	-92.9	0	0	0	111.3	T392 L393 G398 E400 M417 F420 M481	T392-F396 HydrophobicContact CG2-CB 4.42Å; T392-F396 PolarHBondContact O-N 3.04Å; L393-F396 WeakPolarHBondContact CA-O 3.22Å; L393-F396 HydrophobicContact CD2-CD1 4.48Å; L393-F396 VanDerWaalsContact CD2-O 3.27Å; L393-F396 WeakPolarHBondContact CD2-O 3.27Å; F396-G398 VanDerWaalsContact C-N 3.35Å; F396-E400 VanDerWaalsContact CD2-OE2 3.32Å; F396-E400 WeakPolarHBondContact CD2-OE2 3.26Å; F396-M417 HydrophobicContact CD2-CG 4.48Å; F396-M417 HydrophobicContact CE2-CB 4.13Å; F396-M417 HydrophobicContact CE2-CG 3.87Å; F396-F420 AromaticContact CD1-CD1 3.92Å; F396-F420 HydrophobicContact CD1-CD1 3.92Å; F396-F420 AromaticContact CD1-CE1 3.76Å; F396-F420 HydrophobicContact CD1-CE1 3.76Å; F396-F420 HydrophobicContact CD1-CZ 4.33Å; F396-F420 HydrophobicContact CD2-CB 4.1Å; F396-F420 AromaticContact CD2-CD1 3.75Å; F396-F420 HydrophobicContact CD2-CD1 3.75Å; F396-F420 HydrophobicContact CD2-CD2 4.48Å; F396-F420 HydrophobicContact CD2-CE1 4.38Å; F396-F420 AromaticContact CD2-CG 3.82Å; F396-F420 HydrophobicContact CD2-CG 3.82Å; F396-F420 AromaticContact CE1-CD1 3.76Å; F396-F420 HydrophobicContact CE1-CD1 3.76Å; F396-F420 AromaticContact CE1-CE1 3.77Å; F396-F420 HydrophobicContact CE1-CE1 3.77Å; F396-F420 HydrophobicContact CE2-CB 4.01Å; F396-F420 AromaticContact CE2-CD1 3.57Å; F396-F420 HydrophobicContact CE2-CD1 3.57Å; F396-F420 HydrophobicContact CE2-CE1 4.38Å; F396-F420 AromaticContact CE2-CG 3.94Å; F396-F420 HydrophobicContact CE2-CG 3.94Å; F396-F420 AromaticContact CG-CD1 3.91Å; F396-F420 HydrophobicContact CG-CD1 3.91Å; F396-F420 HydrophobicContact CG-CE1 4.08Å; F396-F420 HydrophobicContact CG-CG 4.17Å; F396-F420 HydrophobicContact CG-CZ 4.47Å; F396-F420 AromaticContact CZ-CD1 3.58Å; F396-F420 HydrophobicContact CZ-CD1 3.58Å; F396-F420 HydrophobicContact CZ-CE1 4.09Å; F396-F420 HydrophobicContact CZ-CG 4.4Å; F396-M481 HydrophobicContact CB-CE 4.04Å
397	P	73.3	Confident	85	Confident	67 Å²	67	46.6 Å²	46.6	44%	0.435	25%	0.252	S	S	.	.	T	Hydrogen-bonded Turn	cis	-81.2	-10.7	-9.4	33.8	-35.6	0	0	0	112.9	E400 S401 M417	P397-E400 PolarHBondContact O-N 3.15Å; P397-S401 WeakPolarHBondContact O-CB 3.34Å; P397-S401 PolarHBondContact O-N 2.9Å; P397-S401 PolarHBondContact O-OG 3.09Å; P397-M417 HydrophobicContact CB-SD 4.29Å
398	G	75.8	Confident	84.1	Confident	35 Å²	35	48.1 Å²	48.1	36%	0.361	26%	0.259	S	S	.	.	H	α-helix	trans	-53.9	-67.5	-165.1	0	0	0	0	0	114.8	L395 F396 S401	L395-G398 PolarHBondContact O-N 2.81Å; F396-G398 VanDerWaalsContact C-N 3.35Å; G398-S401 PolarHBondContact O-N 3.17Å; G398-S401 PolarHBondContact O-OG 2.67Å
399	L	80.5	Confident	83.4	Confident	47 Å²	47	49.7 Å²	49.7	25%	0.246	28%	0.275	C	S	.	.	H	α-helix	trans	-66.2	-39.7	-178.6	-174.1	64.5	0	0	0	111.8	L395 S401 E402 I403 F456 V457 V460	L395-L399 HydrophobicContact CD2-CD2 3.64Å; L395-L399 WeakPolarHBondContact O-CB 3.3Å; L395-L399 PolarHBondContact O-N 3.28Å; L399-S401 VanDerWaalsContact C-N 3.26Å; L399-S401 PolarHBondContact O-N 3.2Å; L399-E402 PolarHBondContact O-N 2.91Å; L399-I403 WeakPolarHBondContact O-CG1 3.33Å; L399-F456 HydrophobicContact CD2-CB 3.69Å; L399-V457 HydrophobicContact CD2-CG2 4.43Å; L399-V460 HydrophobicContact CD1-CG2 4.07Å; L399-V460 HydrophobicContact CG-CG2 4.47Å
400	E	82.4	Confident	82.5	Confident	0 Å²	0	54.9 Å²	54.9	0%	0	30%	0.3	C	S	.	.	H	α-helix	trans	-61.6	-32.7	177.5	-72	-165.6	162.6	0	0	112.9	L395 F396 P397 E402 I403 I416 F456 S478 M481	L395-E400 PolarHBondContact O-N 2.99Å; L395-E400 VanDerWaalsContact O-N 3.12Å; F396-E400 VanDerWaalsContact CD2-OE2 3.32Å; F396-E400 WeakPolarHBondContact CD2-OE2 3.26Å; P397-E400 PolarHBondContact O-N 3.15Å; E400-E402 VanDerWaalsContact C-N 3.29Å; E400-E402 PolarHBondContact O-N 3.48Å; E400-I403 PolarHBondContact O-N 3.06Å; E400-I416 HydrophobicContact CB-CG2 3.99Å; E400-I416 HydrophobicContact CG-CG2 3.96Å; E400-I416 VanDerWaalsContact OE2-CG2 3.26Å; E400-I416 WeakPolarHBondContact OE2-CG2 3.13Å; E400-F456 HydrophobicContact CG-CD1 4.36Å; E400-F456 HydrophobicContact CG-CE1 3.86Å; E400-F456 HydrophobicContact CG-CZ 4.22Å; E400-F456 WeakPolarHBondContact OE1-CE1 3.29Å; E400-F456 WeakPolarHBondContact OE1-CZ 3.46Å; E400-S478 WeakPolarHBondContact OE1-CB 3.28Å; E400-S478 PolarHBondContact OE1-OG 2.91Å; E400-S478 PolarHBondContact OE2-OG 2.74Å; E400-M481 WeakPolarHBondContact OE1-CE 3.27Å
401	S	79.3	Confident	82	Confident	43 Å²	43	58.3 Å²	58.3	30%	0.301	31%	0.309	S	S	.	.	H	α-helix	trans	-70.1	-22.8	-179.8	72.7	0	0	0	0	114.3	P397 G398 L399 P413	P397-S401 WeakPolarHBondContact O-CB 3.34Å; P397-S401 PolarHBondContact O-N 2.9Å; P397-S401 PolarHBondContact O-OG 3.09Å; G398-S401 PolarHBondContact O-N 3.17Å; G398-S401 PolarHBondContact O-OG 2.67Å; L399-S401 VanDerWaalsContact C-N 3.26Å; L399-S401 PolarHBondContact O-N 3.2Å; S401-P413 WeakPolarHBondContact O-CG 3.34Å
402	E	78.1	Confident	81.5	Confident	86 Å²	86	57.6 Å²	57.6	40%	0.402	31%	0.306	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.3	-8.5	176.4	-66	-62.6	171.9	0	0	113.4	L399 E400 R404	L399-E402 PolarHBondContact O-N 2.91Å; E400-E402 VanDerWaalsContact C-N 3.29Å; E400-E402 PolarHBondContact O-N 3.48Å; E402-R404 PolarHBondContact O-N 3.1Å
403	I	79.8	Confident	81	Confident	8 Å²	8	58 Å²	58	4%	0.041	31%	0.309	C	S	.	.			trans	-74.9	92.4	-179.6	-54.3	-179.4	0	0	0	110	L399 E400 L412 P413 I416 F456 V460 P474	L399-I403 WeakPolarHBondContact O-CG1 3.33Å; E400-I403 PolarHBondContact O-N 3.06Å; I403-L412 HydrophobicContact CG2-CD2 4.03Å; I403-L412 WeakPolarHBondContact O-CD2 3.44Å; I403-P413 WeakPolarHBondContact O-CD 3.43Å; I403-I416 HydrophobicContact CB-CD1 4.06Å; I403-I416 HydrophobicContact CD1-CD1 4.42Å; I403-I416 HydrophobicContact CG2-CD1 4.08Å; I403-F456 HydrophobicContact CD1-CD1 3.88Å; I403-F456 HydrophobicContact CD1-CE1 4.34Å; I403-V460 HydrophobicContact CD1-CG2 4.42Å; I403-V460 HydrophobicContact CG1-CG2 3.84Å; I403-P474 HydrophobicContact CD1-CB 4.09Å; I403-P474 HydrophobicContact CD1-CG 4.38Å; I403-P474 HydrophobicContact CG2-CB 4.07Å; I403-P474 HydrophobicContact CG2-CG 3.67Å
404	R	77.4	Confident	80.8	Confident	171 Å²	171	56.9 Å²	56.9	65%	0.645	30%	0.303	S	S	*	.			trans	-105.3	144.7	177.3	-58.3	-178.2	-167.6	-141.7	2.3	111.3	E402	E402-R404 PolarHBondContact O-N 3.1Å
405	N	80.9	Confident	80.7	Confident	40 Å²	40	59.4 Å²	59.4	21%	0.214	31%	0.314	C	S	.	.	B	Isolated β-bridge	trans	-132.6	143.3	175.8	-172.5	-36.6	0	0	0	110	A407 L408 G409 L412 S469 P471	N405-A407 PolarHBondContact O-N 3Å; N405-A407 VanDerWaalsContact O-N 3.13Å; N405-A407 PolarHBondContact OD1-N 3.48Å; N405-A407 VanDerWaalsContact OD1-N 3.14Å; N405-L408 PolarHBondContact O-N 2.89Å; N405-G409 WeakPolarHBondContact O-CA 3.48Å; N405-G409 PolarHBondContact O-N 2.97Å; N405-L412 HydrophobicContact CB-CD2 3.54Å; N405-S469 PolarHBondContact ND2-O 3.31Å; N405-P471 WeakPolarHBondContact ND2-CD 3.45Å
406	K	73.8	Confident	80.8	Confident	218 Å²	218	59.4 Å²	59.4	95%	0.948	31%	0.314	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.6	-31	178.2	-63.3	-177.9	-179.6	179	0	113.9
407	A	77.2	Confident	81	Confident	87 Å²	87	59.4 Å²	59.4	72%	0.719	32%	0.315	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.9	-29.1	-177.4	0	0	0	0	0	114.6	N405	N405-A407 PolarHBondContact O-N 3Å; N405-A407 VanDerWaalsContact O-N 3.13Å; N405-A407 PolarHBondContact OD1-N 3.48Å; N405-A407 VanDerWaalsContact OD1-N 3.14Å
408	L	76.9	Confident	81.8	Confident	63 Å²	63	57.2 Å²	57.2	33%	0.33	30%	0.302	S	S	.	.	T	Hydrogen-bonded Turn	trans	-119.1	-16.4	-172.1	-73.7	169.5	0	0	0	113.4	N405 E410 W411 L412 P471	N405-L408 PolarHBondContact O-N 2.89Å; L408-E410 PolarHBondContact O-N 3.49Å; L408-W411 WeakPolarHBondContact O-CB 3.33Å; L408-W411 PolarHBondContact O-N 3.35Å; L408-L412 HydrophobicContact CB-CB 3.84Å; L408-L412 HydrophobicContact CD1-CB 4.26Å; L408-L412 HydrophobicContact CD1-CD1 4.05Å; L408-P471 HydrophobicContact CD1-CB 4.14Å; L408-P471 HydrophobicContact CD1-CG 4.49Å
409	G	81.8	Confident	82.7	Confident	34 Å²	34	57.4 Å²	57.4	35%	0.351	30%	0.297	S	S	.	.	B	Isolated β-bridge	trans	52.4	-122.9	179.4	0	0	0	0	0	112.3	N405 W411	N405-G409 WeakPolarHBondContact O-CA 3.48Å; N405-G409 PolarHBondContact O-N 2.97Å; G409-W411 VanDerWaalsContact C-N 3.3Å; G409-W411 PolarHBondContact O-N 3.45Å
410	E	77.9	Confident	83.3	Confident	121 Å²	121	55.5 Å²	55.5	57%	0.565	29%	0.287	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.2	-17.7	178.1	-57.5	-176.4	167.8	0	0	114.6	K250 L408 L412 I414	K250-E410 IonicContact NZ-OE2 2.89Å; K250-E410 PolarHBondContact NZ-OE2 3.28Å; L408-E410 PolarHBondContact O-N 3.49Å; E410-L412 VanDerWaalsContact C-N 3.32Å; E410-I414 WeakPolarHBondContact O-CG1 3.36Å
411	W	82.6	Confident	83.9	Confident	94 Å²	94	56.7 Å²	56.7	36%	0.356	29%	0.293	S	S	.	.	H	α-helix	trans	-73	-26	179.3	-71.6	98.2	0	0	0	112.5	K250 L251 L408 G409 I414 L415	K250-W411 HydrophobicContact CD-CH2 4.31Å; K250-W411 HydrophobicContact CD-CZ2 4.4Å; K250-W411 HydrophobicContact CG-CH2 4.19Å; K250-W411 HydrophobicContact CG-CZ2 4.39Å; L251-W411 HydrophobicContact CD2-CH2 3.75Å; L251-W411 HydrophobicContact CD2-CZ2 4.23Å; L251-W411 HydrophobicContact CG-CH2 4.05Å; L408-W411 WeakPolarHBondContact O-CB 3.33Å; L408-W411 PolarHBondContact O-N 3.35Å; G409-W411 VanDerWaalsContact C-N 3.3Å; G409-W411 PolarHBondContact O-N 3.45Å; W411-I414 HydrophobicContact CE3-CD1 4.38Å; W411-I414 PolarHBondContact O-N 2.91Å; W411-L415 WeakPolarHBondContact O-CB 3.5Å; W411-L415 VanDerWaalsContact O-CG 3.27Å; W411-L415 WeakPolarHBondContact O-CG 3.26Å; W411-L415 PolarHBondContact O-N 3.36Å
412	L	86.1	Confident	84.7	Confident	2 Å²	2	58.8 Å²	58.8	1%	0.01	30%	0.299	C	S	.	.	H	α-helix	trans	-63	-51.3	-178.9	178.6	61.1	0	0	0	112.1	I403 N405 L408 E410 I414 L415 I416 P471	I403-L412 HydrophobicContact CG2-CD2 4.03Å; I403-L412 WeakPolarHBondContact O-CD2 3.44Å; N405-L412 HydrophobicContact CB-CD2 3.54Å; L408-L412 HydrophobicContact CB-CB 3.84Å; L408-L412 HydrophobicContact CD1-CB 4.26Å; L408-L412 HydrophobicContact CD1-CD1 4.05Å; E410-L412 VanDerWaalsContact C-N 3.32Å; L412-I414 VanDerWaalsContact C-N 3.29Å; L412-I414 PolarHBondContact O-N 2.92Å; L412-L415 PolarHBondContact O-N 3.44Å; L412-I416 HydrophobicContact CD1-CD1 3.72Å; L412-I416 HydrophobicContact CD1-CG1 3.88Å; L412-I416 HydrophobicContact CD2-CD1 4.48Å; L412-I416 HydrophobicContact CG-CD1 3.68Å; L412-I416 HydrophobicContact CG-CG1 4.31Å; L412-I416 VanDerWaalsContact O-CG1 3.24Å; L412-I416 WeakPolarHBondContact O-CG1 3.44Å; L412-I416 PolarHBondContact O-N 3.39Å; L412-P471 HydrophobicContact CD1-CB 4.1Å; L412-P471 HydrophobicContact CD2-CB 4.32Å
413	P	83.9	Confident	85.5	Confident	12 Å²	12	55 Å²	55	8%	0.078	28%	0.282	C	S	.	.	H	α-helix	trans	-52.6	-42.2	170.9	-32.4	38.4	0	0	0	114.3	S401 I403 I416 M417	S401-P413 WeakPolarHBondContact O-CG 3.34Å; I403-P413 WeakPolarHBondContact O-CD 3.43Å; P413-I416 PolarHBondContact O-N 2.94Å; P413-M417 VanDerWaalsContact C-CE 3.49Å; P413-M417 HydrophobicContact CB-CE 3.92Å; P413-M417 WeakPolarHBondContact O-CB 3.37Å; P413-M417 WeakPolarHBondContact O-CE 3.28Å; P413-M417 VanDerWaalsContact O-CG 3.32Å; P413-M417 WeakPolarHBondContact O-CG 3.3Å; P413-M417 PolarHBondContact O-N 3.43Å
414	I	85.1	Confident	86.3	Confident	15 Å²	15	55.1 Å²	55.1	8%	0.077	28%	0.283	C	S	.	.	H	α-helix	trans	-64.8	-44.5	-179.5	-60.6	171.3	0	0	0	110.6	I247 K250 E410 W411 L412 A418	I247-I414 HydrophobicContact CD1-CG2 4.49Å; I247-I414 HydrophobicContact CG1-CG2 3.82Å; K250-I414 HydrophobicContact CD-CD1 4.03Å; E410-I414 WeakPolarHBondContact O-CG1 3.36Å; W411-I414 HydrophobicContact CE3-CD1 4.38Å; W411-I414 PolarHBondContact O-N 2.91Å; L412-I414 VanDerWaalsContact C-N 3.29Å; L412-I414 PolarHBondContact O-N 2.92Å; I414-A418 WeakPolarHBondContact O-CB 3.4Å; I414-A418 PolarHBondContact O-N 2.96Å
415	L	88.3	Confident	87.2	Confident	74 Å²	74	49.5 Å²	49.5	39%	0.387	26%	0.263	S	S	.	.	H	α-helix	trans	-67.8	-39.3	178.1	-69.7	170.5	0	0	0	112.3	W411 L412 T419	W411-L415 WeakPolarHBondContact O-CB 3.5Å; W411-L415 VanDerWaalsContact O-CG 3.27Å; W411-L415 WeakPolarHBondContact O-CG 3.26Å; W411-L415 PolarHBondContact O-N 3.36Å; L412-L415 PolarHBondContact O-N 3.44Å; L415-T419 WeakPolarHBondContact O-CB 3.38Å; L415-T419 PolarHBondContact O-N 3.5Å; L415-T419 PolarHBondContact O-OG1 3.37Å
416	I	90.2	Very high	88	Confident	0 Å²	0	50.6 Å²	50.6	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-62.5	-52	174.8	-65.8	166.2	0	0	0	109.6	E400 I403 L412 P413 A418 T419 F420 P474 S478	E400-I416 HydrophobicContact CB-CG2 3.99Å; E400-I416 HydrophobicContact CG-CG2 3.96Å; E400-I416 VanDerWaalsContact OE2-CG2 3.26Å; E400-I416 WeakPolarHBondContact OE2-CG2 3.13Å; I403-I416 HydrophobicContact CB-CD1 4.06Å; I403-I416 HydrophobicContact CD1-CD1 4.42Å; I403-I416 HydrophobicContact CG2-CD1 4.08Å; L412-I416 HydrophobicContact CD1-CD1 3.72Å; L412-I416 HydrophobicContact CD1-CG1 3.88Å; L412-I416 HydrophobicContact CD2-CD1 4.48Å; L412-I416 HydrophobicContact CG-CD1 3.68Å; L412-I416 HydrophobicContact CG-CG1 4.31Å; L412-I416 VanDerWaalsContact O-CG1 3.24Å; L412-I416 WeakPolarHBondContact O-CG1 3.44Å; L412-I416 PolarHBondContact O-N 3.39Å; P413-I416 PolarHBondContact O-N 2.94Å; I416-A418 VanDerWaalsContact C-N 3.32Å; I416-A418 PolarHBondContact O-N 3.12Å; I416-T419 CarbonylContact O-C 3.6Å; I416-T419 WeakPolarHBondContact O-CA 3.49Å; I416-T419 WeakPolarHBondContact O-CB 3.33Å; I416-T419 PolarHBondContact O-N 3.45Å; I416-F420 PolarHBondContact O-N 3.3Å; I416-P474 HydrophobicContact CD1-CB 3.55Å; I416-P474 HydrophobicContact CG1-CB 4.14Å; I416-S478 WeakPolarHBondContact CG2-OG 3.19Å; I416-S478 PolarHBondContact O-OG 3.35Å
417	M	89.2	Confident	89	Confident	30 Å²	30	40.2 Å²	40.2	15%	0.148	23%	0.226	C	C	.	.	H	α-helix	trans	-59.6	-39.7	178.6	-72.8	-177.8	-88	0	0	112.8	F396 P397 P413 F420 N421	F396-M417 HydrophobicContact CD2-CG 4.48Å; F396-M417 HydrophobicContact CE2-CB 4.13Å; F396-M417 HydrophobicContact CE2-CG 3.87Å; P397-M417 HydrophobicContact CB-SD 4.29Å; P413-M417 VanDerWaalsContact C-CE 3.49Å; P413-M417 HydrophobicContact CB-CE 3.92Å; P413-M417 WeakPolarHBondContact O-CB 3.37Å; P413-M417 WeakPolarHBondContact O-CE 3.28Å; P413-M417 VanDerWaalsContact O-CG 3.32Å; P413-M417 WeakPolarHBondContact O-CG 3.3Å; P413-M417 PolarHBondContact O-N 3.43Å; M417-F420 PolarHBondContact O-N 2.84Å; M417-N421 PolarHBondContact O-N 3.22Å; M417-N421 VanDerWaalsContact O-N 3.08Å; M417-N421 PolarHBondContact O-ND2 2.99Å; M417-N421 VanDerWaalsContact O-ND2 3.17Å
418	A	90.7	Very high	89.9	Confident	21 Å²	21	36.3 Å²	36.3	17%	0.174	19%	0.193	C	C	.	.	H	α-helix	trans	-66.3	-38.1	174.1	0	0	0	0	0	112.3	I247 I414 I416 N421 M422	I247-A418 HydrophobicContact CD1-CB 4.04Å; I414-A418 WeakPolarHBondContact O-CB 3.4Å; I414-A418 PolarHBondContact O-N 2.96Å; I416-A418 VanDerWaalsContact C-N 3.32Å; I416-A418 PolarHBondContact O-N 3.12Å; A418-N421 PolarHBondContact O-N 2.8Å; A418-M422 WeakPolarHBondContact O-CB 3.46Å; A418-M422 PolarHBondContact O-N 3.17Å
419	T	93.9	Very high	90.7	Very high	40 Å²	40	37.1 Å²	37.1	25%	0.245	20%	0.197	C	C	.	.	H	α-helix	trans	-63.9	-44.1	175	-59.3	0	0	0	0	111.1	L415 I416 S423 L479	L415-T419 WeakPolarHBondContact O-CB 3.38Å; L415-T419 PolarHBondContact O-N 3.5Å; L415-T419 PolarHBondContact O-OG1 3.37Å; I416-T419 CarbonylContact O-C 3.6Å; I416-T419 WeakPolarHBondContact O-CA 3.49Å; I416-T419 WeakPolarHBondContact O-CB 3.33Å; I416-T419 PolarHBondContact O-N 3.45Å; T419-S423 VanDerWaalsContact O-CB 3.29Å; T419-S423 WeakPolarHBondContact O-CB 3.37Å; T419-S423 PolarHBondContact O-N 3.47Å; T419-S423 PolarHBondContact O-OG 3.35Å; T419-L479 HydrophobicContact CG2-CB 3.74Å; T419-L479 HydrophobicContact CG2-CD1 4.39Å
420	F	94.8	Very high	91.3	Very high	7 Å²	7	38.8 Å²	38.8	3%	0.031	20%	0.197	C	C	.	.	H	α-helix	trans	-56.9	-55.4	173.7	-179.7	-96.9	0	0	0	111.4	T392 F396 I416 M417 M422 S423 D424 S478 M481 N485	T392-F420 HydrophobicContact CG2-CE1 4.47Å; T392-F420 HydrophobicContact CG2-CE2 3.91Å; T392-F420 HydrophobicContact CG2-CZ 3.52Å; F396-F420 AromaticContact CD1-CD1 3.92Å; F396-F420 HydrophobicContact CD1-CD1 3.92Å; F396-F420 AromaticContact CD1-CE1 3.76Å; F396-F420 HydrophobicContact CD1-CE1 3.76Å; F396-F420 HydrophobicContact CD1-CZ 4.33Å; F396-F420 HydrophobicContact CD2-CB 4.1Å; F396-F420 AromaticContact CD2-CD1 3.75Å; F396-F420 HydrophobicContact CD2-CD1 3.75Å; F396-F420 HydrophobicContact CD2-CD2 4.48Å; F396-F420 HydrophobicContact CD2-CE1 4.38Å; F396-F420 AromaticContact CD2-CG 3.82Å; F396-F420 HydrophobicContact CD2-CG 3.82Å; F396-F420 AromaticContact CE1-CD1 3.76Å; F396-F420 HydrophobicContact CE1-CD1 3.76Å; F396-F420 AromaticContact CE1-CE1 3.77Å; F396-F420 HydrophobicContact CE1-CE1 3.77Å; F396-F420 HydrophobicContact CE2-CB 4.01Å; F396-F420 AromaticContact CE2-CD1 3.57Å; F396-F420 HydrophobicContact CE2-CD1 3.57Å; F396-F420 HydrophobicContact CE2-CE1 4.38Å; F396-F420 AromaticContact CE2-CG 3.94Å; F396-F420 HydrophobicContact CE2-CG 3.94Å; F396-F420 AromaticContact CG-CD1 3.91Å; F396-F420 HydrophobicContact CG-CD1 3.91Å; F396-F420 HydrophobicContact CG-CE1 4.08Å; F396-F420 HydrophobicContact CG-CG 4.17Å; F396-F420 HydrophobicContact CG-CZ 4.47Å; F396-F420 AromaticContact CZ-CD1 3.58Å; F396-F420 HydrophobicContact CZ-CD1 3.58Å; F396-F420 HydrophobicContact CZ-CE1 4.09Å; F396-F420 HydrophobicContact CZ-CG 4.4Å; I416-F420 PolarHBondContact O-N 3.3Å; M417-F420 PolarHBondContact O-N 2.84Å; F420-M422 PolarHBondContact O-N 3.25Å; F420-S423 PolarHBondContact O-N 2.9Å; F420-S423 PolarHBondContact O-OG 3.31Å; F420-D424 HydrophobicContact CE1-CB 4.35Å; F420-D424 HydrophobicContact CZ-CB 4.47Å; F420-D424 VanDerWaalsContact O-CB 3.3Å; F420-D424 WeakPolarHBondContact O-CB 3.47Å; F420-D424 PolarHBondContact O-N 3.07Å; F420-S478 WeakPolarHBondContact CB-OG 3.4Å; F420-M481 HydrophobicContact CD2-CE 3.81Å; F420-M481 HydrophobicContact CE2-CE 3.92Å; F420-M481 HydrophobicContact CE2-CG 4.27Å; F420-N485 HydrophobicContact CE2-CB 4.31Å; F420-N485 HydrophobicContact CZ-CB 4.2Å
421	N	94.3	Very high	92	Very high	25 Å²	25	33.4 Å²	33.4	13%	0.134	17%	0.174	C	C	.	.	H	α-helix	trans	-63.7	-38.4	-175.8	-76.3	-48.1	0	0	0	113	V240 S243 M417 A418 F425	V240-N421 HydrophobicContact CG2-CB 4.46Å; V240-N421 WeakPolarHBondContact CG2-O 3.41Å; S243-N421 PolarHBondContact OG-ND2 3.27Å; M417-N421 PolarHBondContact O-N 3.22Å; M417-N421 VanDerWaalsContact O-N 3.08Å; M417-N421 PolarHBondContact O-ND2 2.99Å; M417-N421 VanDerWaalsContact O-ND2 3.17Å; A418-N421 PolarHBondContact O-N 2.8Å; N421-F425 WeakPolarHBondContact O-CB 3.25Å; N421-F425 PolarHBondContact O-N 3.35Å; N421-F425 VanDerWaalsContact O-N 3.09Å
422	M	95.1	Very high	92.2	Very high	87 Å²	87	31.7 Å²	31.7	43%	0.429	18%	0.179	S	C	.	.	H	α-helix	trans	-67	-42.8	175.9	-170.6	64.8	69.2	0	0	112	V240 A418 F420 F425 V426	V240-M422 HydrophobicContact CG1-CE 3.75Å; V240-M422 HydrophobicContact CG1-SD 4.39Å; V240-M422 HydrophobicContact CG2-CE 4.47Å; V240-M422 HydrophobicContact CG2-SD 4.31Å; A418-M422 WeakPolarHBondContact O-CB 3.46Å; A418-M422 PolarHBondContact O-N 3.17Å; F420-M422 PolarHBondContact O-N 3.25Å; M422-F425 PolarHBondContact O-N 3.41Å; M422-V426 WeakPolarHBondContact O-CG2 3.32Å; M422-V426 PolarHBondContact O-N 3.41Å; M422-V426 VanDerWaalsContact O-N 3.1Å
423	S	96.2	Very high	92.2	Very high	7 Å²	7	36.6 Å²	36.6	5%	0.049	21%	0.205	C	C	.	.	H	α-helix	trans	-73.1	-34.2	179.7	57.6	0	0	0	0	112.8	T419 F420 V426 G427 L479 G482 V483	T419-S423 VanDerWaalsContact O-CB 3.29Å; T419-S423 WeakPolarHBondContact O-CB 3.37Å; T419-S423 PolarHBondContact O-N 3.47Å; T419-S423 PolarHBondContact O-OG 3.35Å; F420-S423 PolarHBondContact O-N 2.9Å; F420-S423 PolarHBondContact O-OG 3.31Å; S423-V426 PolarHBondContact O-N 3.11Å; S423-G427 PolarHBondContact O-N 3.13Å; S423-L479 WeakPolarHBondContact CB-O 3.36Å; S423-L479 PolarHBondContact OG-O 2.68Å; S423-G482 WeakPolarHBondContact OG-CA 3.49Å; S423-V483 VanDerWaalsContact O-CA 3.31Å; S423-V483 WeakPolarHBondContact O-CA 3.48Å; S423-V483 PolarHBondContact O-N 3.14Å
424	D	96.7	Very high	91.8	Very high	9 Å²	9	42.4 Å²	42.4	5%	0.048	24%	0.243	C	C	.	.	H	α-helix	trans	-60.8	-46.9	170.2	-176.5	73.7	0	0	0	111.5	S236 F420 V426 G427 K428 G482 N485 G486	S236-D424 WeakPolarHBondContact CB-OD2 3.35Å; S236-D424 PolarHBondContact OG-OD2 2.95Å; F420-D424 HydrophobicContact CE1-CB 4.35Å; F420-D424 HydrophobicContact CZ-CB 4.47Å; F420-D424 VanDerWaalsContact O-CB 3.3Å; F420-D424 WeakPolarHBondContact O-CB 3.47Å; F420-D424 PolarHBondContact O-N 3.07Å; D424-V426 PolarHBondContact O-N 3.47Å; D424-G427 WeakPolarHBondContact O-CA 3.32Å; D424-G427 PolarHBondContact O-N 2.98Å; D424-K428 WeakPolarHBondContact O-CG 3.41Å; D424-K428 PolarHBondContact O-N 2.9Å; D424-K428 IonicContact OD2-NZ 2.81Å; D424-G482 VanDerWaalsContact CA-O 3.32Å; D424-G482 WeakPolarHBondContact CA-O 3.33Å; D424-N485 WeakPolarHBondContact OD1-CB 3.45Å; D424-N485 PolarHBondContact OD1-ND2 3.3Å; D424-G486 VanDerWaalsContact OD1-CA 3.24Å; D424-G486 WeakPolarHBondContact OD1-CA 3.48Å; D424-G486 PolarHBondContact OD1-N 2.9Å
425	F	95.9	Very high	91.6	Very high	54 Å²	54	47.2 Å²	47.2	24%	0.237	26%	0.261	C	S	.	.	H	α-helix	trans	-55.9	-46	172.6	172.1	-106.3	0	0	0	112.6	T233 T237 V240 N421 M422 G427 K428 I429	T233-F425 HydrophobicContact CG2-CD2 4.01Å; T233-F425 HydrophobicContact CG2-CE2 3.63Å; T237-F425 VanDerWaalsContact OG1-CE2 3.22Å; T237-F425 WeakPolarHBondContact OG1-CE2 3.4Å; V240-F425 HydrophobicContact CG2-CB 3.89Å; V240-F425 HydrophobicContact CG2-CG 4.3Å; N421-F425 WeakPolarHBondContact O-CB 3.25Å; N421-F425 PolarHBondContact O-N 3.35Å; N421-F425 VanDerWaalsContact O-N 3.09Å; M422-F425 PolarHBondContact O-N 3.41Å; F425-G427 VanDerWaalsContact C-N 3.35Å; F425-G427 PolarHBondContact O-N 3.02Å; F425-K428 PolarHBondContact O-N 3.25Å; F425-I429 HydrophobicContact CD1-CD1 4.01Å; F425-I429 HydrophobicContact CE1-CD1 3.51Å; F425-I429 HydrophobicContact CE2-CD1 4.06Å; F425-I429 HydrophobicContact CZ-CD1 3.55Å; F425-I429 HydrophobicContact CZ-CG1 4.48Å; F425-I429 PolarHBondContact O-N 2.82Å
426	V	96.6	Very high	91.3	Very high	63 Å²	63	48.5 Å²	48.5	38%	0.382	27%	0.268	S	S	.	.	H	α-helix	trans	-60.4	-43	173.1	172.8	0	0	0	0	111.4	M422 S423 D424 K428 I429 L430	M422-V426 WeakPolarHBondContact O-CG2 3.32Å; M422-V426 PolarHBondContact O-N 3.41Å; M422-V426 VanDerWaalsContact O-N 3.1Å; S423-V426 PolarHBondContact O-N 3.11Å; D424-V426 PolarHBondContact O-N 3.47Å; V426-K428 VanDerWaalsContact C-N 3.3Å; V426-K428 PolarHBondContact O-N 2.92Å; V426-I429 PolarHBondContact O-N 3.48Å; V426-L430 HydrophobicContact CG1-CD1 4.11Å; V426-L430 HydrophobicContact CG1-CG 4.39Å; V426-L430 WeakPolarHBondContact O-CG 3.49Å; V426-L430 PolarHBondContact O-N 3.48Å
427	G	96.2	Very high	91.2	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-58.5	-38.7	176.1	0	0	0	0	0	113.3	S423 D424 F425 L430 A431 V483 G486 Y487	S423-G427 PolarHBondContact O-N 3.13Å; D424-G427 WeakPolarHBondContact O-CA 3.32Å; D424-G427 PolarHBondContact O-N 2.98Å; F425-G427 VanDerWaalsContact C-N 3.35Å; F425-G427 PolarHBondContact O-N 3.02Å; G427-L430 PolarHBondContact O-N 2.92Å; G427-A431 PolarHBondContact O-N 3.38Å; G427-V483 WeakPolarHBondContact CA-O 3.26Å; G427-G486 VanDerWaalsContact C-C 3.48Å; G427-G486 CarbonylContact O-C 3.54Å; G427-Y487 WeakPolarHBondContact O-CA 3.41Å; G427-Y487 PolarHBondContact O-N 3.02Å
428	K	94.9	Very high	91.3	Very high	5 Å²	5	51.4 Å²	51.4	2%	0.022	29%	0.286	C	S	.	.	H	α-helix	trans	-73.8	-30.5	176.5	-61.4	-154.7	-179.3	158.1	0	113.5	Q229 M232 E235 S236 D424 F425 V426 A431 S490	Q229-K428 PolarHBondContact NE2-O 3.17Å; M232-K428 VanDerWaalsContact C-CD 3.42Å; M232-K428 HydrophobicContact CB-CD 4Å; M232-K428 WeakPolarHBondContact O-CD 3.46Å; M232-K428 PolarHBondContact O-NZ 3.13Å; E235-K428 IonicContact OE2-NZ 3.94Å; E235-K428 PolarHBondContact OE2-NZ 2.97Å; S236-K428 WeakPolarHBondContact OG-CD 3.38Å; S236-K428 WeakPolarHBondContact OG-CE 3.28Å; S236-K428 PolarHBondContact OG-NZ 3.07Å; D424-K428 WeakPolarHBondContact O-CG 3.41Å; D424-K428 PolarHBondContact O-N 2.9Å; D424-K428 IonicContact OD2-NZ 2.81Å; F425-K428 PolarHBondContact O-N 3.25Å; V426-K428 VanDerWaalsContact C-N 3.3Å; V426-K428 PolarHBondContact O-N 2.92Å; K428-A431 WeakPolarHBondContact O-CB 3.44Å; K428-A431 PolarHBondContact O-N 2.91Å; K428-S490 WeakPolarHBondContact CD-OG 3.48Å; K428-S490 VanDerWaalsContact CG-OG 3.31Å; K428-S490 WeakPolarHBondContact CG-OG 3.32Å
429	I	93.9	Very high	91.2	Very high	79 Å²	79	50.8 Å²	50.8	41%	0.405	28%	0.281	S	S	.	.	H	α-helix	trans	-66.5	-45	167.9	-67.8	168.9	0	0	0	110.3	T233 F425 V426 A431 A432	T233-I429 HydrophobicContact CG2-CG1 4.08Å; F425-I429 HydrophobicContact CD1-CD1 4.01Å; F425-I429 HydrophobicContact CE1-CD1 3.51Å; F425-I429 HydrophobicContact CE2-CD1 4.06Å; F425-I429 HydrophobicContact CZ-CD1 3.55Å; F425-I429 HydrophobicContact CZ-CG1 4.48Å; F425-I429 PolarHBondContact O-N 2.82Å; V426-I429 PolarHBondContact O-N 3.48Å; I429-A431 PolarHBondContact O-N 3.44Å; I429-A432 WeakPolarHBondContact O-CB 3.49Å; I429-A432 PolarHBondContact O-N 3.08Å
430	L	94.1	Very high	91.1	Very high	70 Å²	70	51.2 Å²	51.2	37%	0.366	29%	0.293	S	S	.	.	H	α-helix	trans	-61.1	-28.5	176.7	-69.6	172	0	0	0	112.5	V426 G427 A432 L433 V483 Y487	V426-L430 HydrophobicContact CG1-CD1 4.11Å; V426-L430 HydrophobicContact CG1-CG 4.39Å; V426-L430 WeakPolarHBondContact O-CG 3.49Å; V426-L430 PolarHBondContact O-N 3.48Å; G427-L430 PolarHBondContact O-N 2.92Å; L430-A432 PolarHBondContact O-N 3.39Å; L430-L433 HydrophobicContact CD2-CD1 4.13Å; L430-L433 WeakPolarHBondContact O-CB 3.26Å; L430-L433 WeakPolarHBondContact O-CG 3.32Å; L430-L433 PolarHBondContact O-N 3.05Å; L430-L433 VanDerWaalsContact O-N 3.08Å; L430-V483 HydrophobicContact CD1-CG1 4.09Å; L430-Y487 HydrophobicContact CB-CD2 3.94Å; L430-Y487 HydrophobicContact CB-CE2 4.35Å; L430-Y487 WeakPolarHBondContact O-CE2 3.43Å
431	A	92.5	Very high	91.1	Very high	8 Å²	8	57.6 Å²	57.6	7%	0.066	32%	0.317	C	S	.	.	T	Hydrogen-bonded Turn	trans	-67.4	-7.2	172.7	0	0	0	0	0	114.4	G427 K428 I429 L433 Y487 V491 I494	G427-A431 PolarHBondContact O-N 3.38Å; K428-A431 WeakPolarHBondContact O-CB 3.44Å; K428-A431 PolarHBondContact O-N 2.91Å; I429-A431 PolarHBondContact O-N 3.44Å; A431-L433 VanDerWaalsContact C-N 3.3Å; A431-Y487 HydrophobicContact CB-CD2 4.23Å; A431-V491 HydrophobicContact CB-CG2 3.85Å; A431-I494 HydrophobicContact CB-CD1 4.06Å
432	A	87.7	Confident	91.2	Very high	57 Å²	57	56.4 Å²	56.4	47%	0.471	31%	0.311	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.8	-18.2	168.1	0	0	0	0	0	113.3	Q229 I429 L430	Q229-A432 HydrophobicContact CG-CB 4.01Å; I429-A432 WeakPolarHBondContact O-CB 3.49Å; I429-A432 PolarHBondContact O-N 3.08Å; L430-A432 PolarHBondContact O-N 3.39Å
433	L	86.6	Confident	91.2	Very high	106 Å²	106	53.6 Å²	53.6	56%	0.555	30%	0.297	S	S	*	.	S	Bend	trans	-63.9	129.6	178.4	-65.2	173.1	0	0	0	109.9	L430 A431 Y435	L430-L433 HydrophobicContact CD2-CD1 4.13Å; L430-L433 WeakPolarHBondContact O-CB 3.26Å; L430-L433 WeakPolarHBondContact O-CG 3.32Å; L430-L433 PolarHBondContact O-N 3.05Å; L430-L433 VanDerWaalsContact O-N 3.08Å; A431-L433 VanDerWaalsContact C-N 3.3Å; L433-Y435 PolarHBondContact O-N 3.46Å
434	P	74.8	Confident	91.2	Very high	134 Å²	134	59.5 Å²	59.5	87%	0.87	32%	0.323	S	S	*	.			trans	-79.5	61.7	-170.1	33.6	-37.9	0	0	0	112.6
435	Y	80.4	Confident	91.2	Very high	116 Å²	116	62.6 Å²	62.6	46%	0.455	34%	0.336	S	S	.	.			trans	-104.2	109.1	173.7	-171.8	-81.3	0	0	0	110	L433 W437 Q495	L433-Y435 PolarHBondContact O-N 3.46Å; Y435-W437 AromaticContact CD1-CD1 3.41Å; Y435-W437 VanDerWaalsContact CD1-CD1 3.41Å; Y435-W437 AromaticContact CD1-CD2 3.97Å; Y435-W437 HydrophobicContact CD1-CD2 3.97Å; Y435-W437 AromaticContact CD1-CE2 3.68Å; Y435-W437 AromaticContact CD1-CG 3.8Å; Y435-W437 HydrophobicContact CD1-CG 3.8Å; Y435-W437 HydrophobicContact CD1-CZ2 4.41Å; Y435-W437 AromaticContact CD1-NE1 3.32Å; Y435-W437 VanDerWaalsContact CD1-NE1 3.32Å; Y435-W437 AromaticContact CE1-CD1 3.98Å; Y435-W437 AromaticContact CE1-CD2 3.74Å; Y435-W437 HydrophobicContact CE1-CD2 3.74Å; Y435-W437 AromaticContact CE1-CE2 3.68Å; Y435-W437 HydrophobicContact CE1-CE3 4.29Å; Y435-W437 AromaticContact CE1-CG 3.93Å; Y435-W437 HydrophobicContact CE1-CG 3.93Å; Y435-W437 HydrophobicContact CE1-CZ2 4.17Å; Y435-W437 AromaticContact CE1-NE1 3.83Å; Y435-W437 PolarHBondContact O-N 2.93Å; Y435-Q495 PolarHBondContact O-NE2 3.39Å
436	D	81.9	Confident	91.2	Very high	100 Å²	100	60 Å²	60	54%	0.535	32%	0.324	S	S	.	.			trans	-75.7	112.7	176.6	-86.2	-40.4	0	0	0	110.5	K225	K225-D436 IonicContact NZ-OD1 2.74Å; K225-D436 PolarHBondContact NZ-OD1 2.87Å; K225-D436 IonicContact NZ-OD2 3.93Å
437	W	88.5	Confident	91.2	Very high	36 Å²	36	59.9 Å²	59.9	14%	0.136	33%	0.325	C	S	.	.			trans	-91.9	144.2	179.9	-77.4	87.1	0	0	0	110.3	Y381 Y435 R441 L442 F445 Y487 F488 V491 Q495	Y381-W437 PolarHBondContact OH-O 3.29Å; Y435-W437 AromaticContact CD1-CD1 3.41Å; Y435-W437 VanDerWaalsContact CD1-CD1 3.41Å; Y435-W437 AromaticContact CD1-CD2 3.97Å; Y435-W437 HydrophobicContact CD1-CD2 3.97Å; Y435-W437 AromaticContact CD1-CE2 3.68Å; Y435-W437 AromaticContact CD1-CG 3.8Å; Y435-W437 HydrophobicContact CD1-CG 3.8Å; Y435-W437 HydrophobicContact CD1-CZ2 4.41Å; Y435-W437 AromaticContact CD1-NE1 3.32Å; Y435-W437 VanDerWaalsContact CD1-NE1 3.32Å; Y435-W437 AromaticContact CE1-CD1 3.98Å; Y435-W437 AromaticContact CE1-CD2 3.74Å; Y435-W437 HydrophobicContact CE1-CD2 3.74Å; Y435-W437 AromaticContact CE1-CE2 3.68Å; Y435-W437 HydrophobicContact CE1-CE3 4.29Å; Y435-W437 AromaticContact CE1-CG 3.93Å; Y435-W437 HydrophobicContact CE1-CG 3.93Å; Y435-W437 HydrophobicContact CE1-CZ2 4.17Å; Y435-W437 AromaticContact CE1-NE1 3.83Å; Y435-W437 PolarHBondContact O-N 2.93Å; W437-R441 HydrophobicContact CE3-CB 3.7Å; W437-R441 HydrophobicContact CZ3-CB 3.93Å; W437-L442 HydrophobicContact CB-CD1 3.75Å; W437-L442 HydrophobicContact CB-CD2 3.8Å; W437-L442 HydrophobicContact CB-CG 3.57Å; W437-L442 HydrophobicContact CD2-CD2 3.96Å; W437-L442 HydrophobicContact CD2-CG 4.39Å; W437-L442 HydrophobicContact CE3-CD2 4.36Å; W437-L442 HydrophobicContact CG-CD2 3.71Å; W437-L442 HydrophobicContact CG-CG 4.02Å; W437-F445 AromaticContact CH2-CD2 3.93Å; W437-F445 HydrophobicContact CH2-CD2 3.93Å; W437-F445 AromaticContact CH2-CE2 3.87Å; W437-F445 HydrophobicContact CH2-CE2 3.87Å; W437-F445 AromaticContact CZ3-CD2 3.61Å; W437-F445 HydrophobicContact CZ3-CD2 3.61Å; W437-F445 AromaticContact CZ3-CE2 3.62Å; W437-F445 HydrophobicContact CZ3-CE2 3.62Å; W437-Y487 AromaticContact CE2-CE1 3.92Å; W437-Y487 AromaticContact CZ2-CE1 4Å; W437-Y487 HydrophobicContact CZ2-CE1 4Å; W437-Y487 AromaticContact NE1-CE1 3.49Å; W437-Y487 AromaticContact NE1-CZ 3.6Å; W437-Y487 PolarHBondContact NE1-OH 2.82Å; W437-F488 HydrophobicContact CH2-CE1 4.45Å; W437-F488 HydrophobicContact CZ2-CE1 4.44Å; W437-V491 HydrophobicContact CB-CG1 4.39Å; W437-V491 HydrophobicContact CG-CG1 4.26Å; W437-Q495 VanDerWaalsContact N-OE1 3.12Å; W437-Q495 PolarHBondContact O-OE1 3.42Å
438	S	91.4	Very high	91.2	Very high	56 Å²	56	64.1 Å²	64.1	39%	0.392	35%	0.347	S	S	.	.			trans	-75.5	137.1	163.8	64.3	0	0	0	0	110	G440 R441 L442	S438-G440 PolarHBondContact O-N 3.19Å; S438-G440 VanDerWaalsContact O-N 3.12Å; S438-R441 PolarHBondContact O-N 2.89Å; S438-R441 WeakPolarHBondContact OG-CD 3.08Å; S438-R441 VanDerWaalsContact OG-CG 3.28Å; S438-R441 WeakPolarHBondContact OG-CG 3.43Å; S438-L442 PolarHBondContact O-N 3.05Å; S438-L442 VanDerWaalsContact O-N 3.11Å
439	G	89	Confident	91.3	Very high	7 Å²	7	64.1 Å²	64.1	7%	0.072	35%	0.347	C	S	.	.	H	α-helix	trans	-54	-34.5	-179.5	0	0	0	0	0	113.9	Y381 L442 L443	Y381-G439 PolarHBondContact OH-N 2.87Å; G439-L442 PolarHBondContact O-N 2.95Å; G439-L443 WeakPolarHBondContact O-CB 3.34Å; G439-L443 PolarHBondContact O-N 3.35Å
440	G	92.5	Very high	91.4	Very high	49 Å²	49	64.1 Å²	64.1	51%	0.505	35%	0.351	S	S	.	.	H	α-helix	trans	-65.2	-38.1	175	0	0	0	0	0	114	S438 F444	S438-G440 PolarHBondContact O-N 3.19Å; S438-G440 VanDerWaalsContact O-N 3.12Å; G440-F444 WeakPolarHBondContact O-CB 3.32Å; G440-F444 PolarHBondContact O-N 3.48Å
441	R	94.7	Very high	91.5	Very high	142 Å²	142	64.2 Å²	64.2	54%	0.536	35%	0.354	S	S	.	.	H	α-helix	trans	-69.6	-42.2	174.6	-73.3	177.6	-174.1	175.3	3.3	111.2	W437 S438 L443 F444 F445	W437-R441 HydrophobicContact CE3-CB 3.7Å; W437-R441 HydrophobicContact CZ3-CB 3.93Å; S438-R441 PolarHBondContact O-N 2.89Å; S438-R441 WeakPolarHBondContact OG-CD 3.08Å; S438-R441 VanDerWaalsContact OG-CG 3.28Å; S438-R441 WeakPolarHBondContact OG-CG 3.43Å; R441-L443 VanDerWaalsContact C-N 3.34Å; R441-L443 PolarHBondContact O-N 2.76Å; R441-F444 PolarHBondContact O-N 3.42Å; R441-F445 VanDerWaalsContact O-CD2 3.26Å; R441-F445 WeakPolarHBondContact O-CD2 3.36Å; R441-F445 PolarHBondContact O-N 3.31Å
442	L	94.7	Very high	91.6	Very high	0 Å²	0	65 Å²	65	0%	0	36%	0.356	C	S	.	.	H	α-helix	trans	-57.8	-48	174.3	-72.8	167.6	0	0	0	111.3	Y381 W437 S438 G439 F444 F445 S446 F488 V491 P492	Y381-L442 HydrophobicContact CD1-CD1 3.62Å; Y381-L442 HydrophobicContact CE1-CD1 3.58Å; W437-L442 HydrophobicContact CB-CD1 3.75Å; W437-L442 HydrophobicContact CB-CD2 3.8Å; W437-L442 HydrophobicContact CB-CG 3.57Å; W437-L442 HydrophobicContact CD2-CD2 3.96Å; W437-L442 HydrophobicContact CD2-CG 4.39Å; W437-L442 HydrophobicContact CE3-CD2 4.36Å; W437-L442 HydrophobicContact CG-CD2 3.71Å; W437-L442 HydrophobicContact CG-CG 4.02Å; S438-L442 PolarHBondContact O-N 3.05Å; S438-L442 VanDerWaalsContact O-N 3.11Å; G439-L442 PolarHBondContact O-N 2.95Å; L442-F444 PolarHBondContact O-N 3.37Å; L442-F445 PolarHBondContact O-N 2.92Å; L442-S446 WeakPolarHBondContact O-CB 3.38Å; L442-S446 PolarHBondContact O-N 3.33Å; L442-S446 PolarHBondContact O-OG 3.22Å; L442-F488 HydrophobicContact CD2-CD1 3.88Å; L442-F488 HydrophobicContact CD2-CE1 4.26Å; L442-V491 HydrophobicContact CD1-CG1 4.1Å; L442-V491 HydrophobicContact CD2-CB 4.17Å; L442-V491 HydrophobicContact CD2-CG1 3.79Å; L442-P492 HydrophobicContact CD1-CG 4.2Å
443	L	96.1	Very high	91.7	Very high	27 Å²	27	64.8 Å²	64.8	14%	0.141	35%	0.347	C	S	.	.	H	α-helix	trans	-60.3	-44.4	177	178.7	59.9	0	0	0	111.8	W379 L383 G439 R441 F445 S446 C447	W379-L443 HydrophobicContact CH2-CD2 4.34Å; W379-L443 HydrophobicContact CZ3-CD2 3.97Å; L383-L443 HydrophobicContact CB-CD1 4.04Å; L383-L443 HydrophobicContact CD2-CD1 3.82Å; L383-L443 HydrophobicContact CD2-CD2 3.91Å; L383-L443 HydrophobicContact CG-CD1 3.66Å; G439-L443 WeakPolarHBondContact O-CB 3.34Å; G439-L443 PolarHBondContact O-N 3.35Å; R441-L443 VanDerWaalsContact C-N 3.34Å; R441-L443 PolarHBondContact O-N 2.76Å; L443-F445 PolarHBondContact O-N 2.7Å; L443-S446 WeakPolarHBondContact O-CB 3.32Å; L443-S446 PolarHBondContact O-N 3.32Å; L443-C447 WeakPolarHBondContact O-CB 3.36Å; L443-C447 PolarHBondContact O-N 2.96Å; L443-C447 PolarHBondContact O-SG 3Å
444	F	96.6	Very high	92	Very high	132 Å²	132	62.9 Å²	62.9	58%	0.579	34%	0.34	S	S	*	.	H	α-helix	trans	-57.5	-50.6	176.3	175.8	-97.6	0	0	0	112.3	G440 R441 L442 S446 C447 L448	G440-F444 WeakPolarHBondContact O-CB 3.32Å; G440-F444 PolarHBondContact O-N 3.48Å; R441-F444 PolarHBondContact O-N 3.42Å; L442-F444 PolarHBondContact O-N 3.37Å; F444-S446 VanDerWaalsContact C-N 3.34Å; F444-S446 PolarHBondContact O-N 3.31Å; F444-C447 PolarHBondContact O-N 3.45Å; F444-L448 PolarHBondContact O-N 3.26Å
445	F	95.8	Very high	92.8	Very high	74 Å²	74	58.8 Å²	58.8	33%	0.325	31%	0.311	S	S	.	.	H	α-helix	trans	-68.6	-31.6	178	-75.3	-69.1	0	0	0	113	W437 R441 L442 L443 L448 R449 F488	W437-F445 AromaticContact CH2-CD2 3.93Å; W437-F445 HydrophobicContact CH2-CD2 3.93Å; W437-F445 AromaticContact CH2-CE2 3.87Å; W437-F445 HydrophobicContact CH2-CE2 3.87Å; W437-F445 AromaticContact CZ3-CD2 3.61Å; W437-F445 HydrophobicContact CZ3-CD2 3.61Å; W437-F445 AromaticContact CZ3-CE2 3.62Å; W437-F445 HydrophobicContact CZ3-CE2 3.62Å; R441-F445 VanDerWaalsContact O-CD2 3.26Å; R441-F445 WeakPolarHBondContact O-CD2 3.36Å; R441-F445 PolarHBondContact O-N 3.31Å; L442-F445 PolarHBondContact O-N 2.92Å; L443-F445 PolarHBondContact O-N 2.7Å; F445-L448 HydrophobicContact CD1-CD2 4.15Å; F445-L448 HydrophobicContact CE1-CD2 4.43Å; F445-L448 PolarHBondContact O-N 2.89Å; F445-R449 PolarHBondContact O-N 3.49Å; F445-F488 HydrophobicContact CB-CD1 4.19Å; F445-F488 HydrophobicContact CB-CE1 3.57Å; F445-F488 HydrophobicContact CB-CE2 3.95Å; F445-F488 HydrophobicContact CB-CZ 3.43Å; F445-F488 VanDerWaalsContact CB-CZ 3.43Å; F445-F488 HydrophobicContact CD1-CZ 4.4Å; F445-F488 HydrophobicContact CD2-CE1 4.42Å; F445-F488 HydrophobicContact CD2-CZ 4.4Å; F445-F488 HydrophobicContact CG-CE1 4.17Å; F445-F488 AromaticContact CG-CZ 3.85Å; F445-F488 HydrophobicContact CG-CZ 3.85Å
446	S	96.4	Very high	93.1	Very high	0 Å²	0	53.2 Å²	53.2	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-63.4	-43.5	172.2	-57	0	0	0	0	111.4	S384 T388 L442 L443 F444 R449	S384-S446 WeakPolarHBondContact O-CB 3.27Å; S384-S446 PolarHBondContact O-OG 3.44Å; S384-S446 PolarHBondContact OG-OG 3.08Å; T388-S446 VanDerWaalsContact OG1-CB 3.32Å; T388-S446 WeakPolarHBondContact OG1-CB 3.39Å; T388-S446 PolarHBondContact OG1-OG 3.27Å; T388-S446 VanDerWaalsContact OG1-OG 3.12Å; L442-S446 WeakPolarHBondContact O-CB 3.38Å; L442-S446 PolarHBondContact O-N 3.33Å; L442-S446 PolarHBondContact O-OG 3.22Å; L443-S446 WeakPolarHBondContact O-CB 3.32Å; L443-S446 PolarHBondContact O-N 3.32Å; F444-S446 VanDerWaalsContact C-N 3.34Å; F444-S446 PolarHBondContact O-N 3.31Å; S446-R449 VanDerWaalsContact O-CB 3.24Å; S446-R449 WeakPolarHBondContact O-CB 3.49Å; S446-R449 WeakPolarHBondContact O-CD 3.08Å; S446-R449 VanDerWaalsContact O-CG 3.29Å; S446-R449 WeakPolarHBondContact O-CG 3.23Å; S446-R449 PolarHBondContact O-N 3.42Å
447	C	96.7	Very high	93.3	Very high	59 Å²	59	51.6 Å²	51.6	40%	0.399	28%	0.283	S	S	.	.	H	α-helix	trans	-67.6	-36.4	175.3	-68.5	0	0	0	0	112.2	L443 F444 R449 V450	L443-C447 WeakPolarHBondContact O-CB 3.36Å; L443-C447 PolarHBondContact O-N 2.96Å; L443-C447 PolarHBondContact O-SG 3Å; F444-C447 PolarHBondContact O-N 3.45Å; C447-R449 PolarHBondContact O-N 2.85Å; C447-R449 VanDerWaalsContact O-N 3.15Å; C447-V450 WeakPolarHBondContact O-CB 3.3Å; C447-V450 VanDerWaalsContact O-CG1 3.26Å; C447-V450 WeakPolarHBondContact O-CG1 3.36Å; C447-V450 PolarHBondContact O-N 3.32Å
448	L	96.8	Very high	93.2	Very high	89 Å²	89	53.6 Å²	53.6	47%	0.466	30%	0.295	S	S	.	.	H	α-helix	trans	-60.1	-24	177.4	-173.1	61.5	0	0	0	112.8	F444 F445 V450 V451	F444-L448 PolarHBondContact O-N 3.26Å; F445-L448 HydrophobicContact CD1-CD2 4.15Å; F445-L448 HydrophobicContact CE1-CD2 4.43Å; F445-L448 PolarHBondContact O-N 2.89Å; L448-V450 PolarHBondContact O-N 3.33Å; L448-V451 HydrophobicContact CD1-CG2 4.18Å; L448-V451 WeakPolarHBondContact O-CB 3.33Å; L448-V451 WeakPolarHBondContact O-CG2 3.46Å; L448-V451 PolarHBondContact O-N 2.87Å
449	R	96.9	Very high	92.8	Very high	6 Å²	6	51.4 Å²	51.4	2%	0.023	28%	0.279	C	S	.	.	G	3₁₀ helix	trans	-55	-20.6	171.4	-59.8	175.2	62.7	69.5	1	113.4	I391 T392 F445 S446 C447 V451 F452 M481 T484 N485	I391-R449 HydrophobicContact CB-CB 4.48Å; I391-R449 HydrophobicContact CD1-CB 3.88Å; I391-R449 HydrophobicContact CG2-CB 4.03Å; T392-R449 PolarHBondContact OG1-NH2 3.31Å; F445-R449 PolarHBondContact O-N 3.49Å; S446-R449 VanDerWaalsContact O-CB 3.24Å; S446-R449 WeakPolarHBondContact O-CB 3.49Å; S446-R449 WeakPolarHBondContact O-CD 3.08Å; S446-R449 VanDerWaalsContact O-CG 3.29Å; S446-R449 WeakPolarHBondContact O-CG 3.23Å; S446-R449 PolarHBondContact O-N 3.42Å; C447-R449 PolarHBondContact O-N 2.85Å; C447-R449 VanDerWaalsContact O-N 3.15Å; R449-V451 PolarHBondContact O-N 3.23Å; R449-F452 HydrophobicContact CB-CD2 4.03Å; R449-F452 HydrophobicContact CB-CE2 4.27Å; R449-F452 HydrophobicContact CG-CE2 4.38Å; R449-F452 WeakPolarHBondContact O-CB 3.47Å; R449-F452 WeakPolarHBondContact O-CD2 3.32Å; R449-F452 PolarHBondContact O-N 2.7Å; R449-M481 PolarHBondContact NH1-O 3.5Å; R449-M481 PolarHBondContact NH2-O 3.12Å; R449-M481 VanDerWaalsContact NH2-O 3.07Å; R449-T484 VanDerWaalsContact NH1-CB 3.26Å; R449-T484 PolarHBondContact NH1-O 2.7Å; R449-T484 PolarHBondContact NH1-OG1 2.78Å; R449-N485 VanDerWaalsContact NH1-N 3.16Å
450	V	95.1	Very high	92.4	Very high	78 Å²	78	52.9 Å²	52.9	47%	0.473	29%	0.287	S	S	.	.	G	3₁₀ helix	trans	-57.1	-24.3	179.1	76.4	0	0	0	0	112.1	I391 C447 L448 F452 I453 P454	I391-V450 HydrophobicContact CD1-CB 4.24Å; C447-V450 WeakPolarHBondContact O-CB 3.3Å; C447-V450 VanDerWaalsContact O-CG1 3.26Å; C447-V450 WeakPolarHBondContact O-CG1 3.36Å; C447-V450 PolarHBondContact O-N 3.32Å; L448-V450 PolarHBondContact O-N 3.33Å; V450-F452 PolarHBondContact O-N 3.48Å; V450-I453 HydrophobicContact CG2-CD1 3.98Å; V450-I453 WeakPolarHBondContact O-CB 3.33Å; V450-I453 PolarHBondContact O-N 3.1Å; V450-P454 VanDerWaalsContact O-CD 3.28Å; V450-P454 WeakPolarHBondContact O-CD 3.42Å
451	V	95.7	Very high	91.5	Very high	72 Å²	72	58.1 Å²	58.1	44%	0.436	29%	0.292	S	S	.	.	G	3₁₀ helix	trans	-60.2	-25.1	173.6	177.2	0	0	0	0	112.8	L448 R449 I453 P454 L455	L448-V451 HydrophobicContact CD1-CG2 4.18Å; L448-V451 WeakPolarHBondContact O-CB 3.33Å; L448-V451 WeakPolarHBondContact O-CG2 3.46Å; L448-V451 PolarHBondContact O-N 2.87Å; R449-V451 PolarHBondContact O-N 3.23Å; V451-I453 PolarHBondContact O-N 3.49Å; V451-P454 VanDerWaalsContact O-CD 3.26Å; V451-P454 WeakPolarHBondContact O-CD 3.43Å; V451-P454 WeakPolarHBondContact O-CG 3.4Å; V451-L455 HydrophobicContact CG1-CD1 3.99Å; V451-L455 HydrophobicContact CG1-CG 4.36Å; V451-L455 VanDerWaalsContact O-CG 3.3Å; V451-L455 WeakPolarHBondContact O-CG 3.48Å; V451-L455 PolarHBondContact O-N 3.27Å
452	F	94.6	Very high	90.3	Very high	25 Å²	25	53.5 Å²	53.5	11%	0.11	28%	0.281	C	S	.	.	H	α-helix	trans	-62.7	-31.1	173.5	-68.2	-59.7	0	0	0	112.5	L395 R449 V450 L455 F456 L480 M481	L395-F452 HydrophobicContact CD1-CB 3.74Å; R449-F452 HydrophobicContact CB-CD2 4.03Å; R449-F452 HydrophobicContact CB-CE2 4.27Å; R449-F452 HydrophobicContact CG-CE2 4.38Å; R449-F452 WeakPolarHBondContact O-CB 3.47Å; R449-F452 WeakPolarHBondContact O-CD2 3.32Å; R449-F452 PolarHBondContact O-N 2.7Å; V450-F452 PolarHBondContact O-N 3.48Å; F452-L455 HydrophobicContact CD1-CD1 4.44Å; F452-L455 PolarHBondContact O-N 2.73Å; F452-F456 HydrophobicContact CB-CD2 4.24Å; F452-F456 HydrophobicContact CB-CE2 4.33Å; F452-F456 VanDerWaalsContact O-CD2 3.29Å; F452-F456 WeakPolarHBondContact O-CD2 3.43Å; F452-F456 PolarHBondContact O-N 3.28Å; F452-L480 HydrophobicContact CE1-CB 3.9Å; F452-L480 HydrophobicContact CZ-CB 4.1Å; F452-M481 HydrophobicContact CB-SD 4.48Å; F452-M481 HydrophobicContact CD1-CB 4.16Å; F452-M481 HydrophobicContact CD2-CB 4.18Å; F452-M481 HydrophobicContact CD2-CG 4.06Å; F452-M481 HydrophobicContact CE1-CB 4.12Å; F452-M481 HydrophobicContact CE2-CB 4.14Å; F452-M481 HydrophobicContact CE2-CG 4.32Å; F452-M481 HydrophobicContact CG-CB 4.22Å; F452-M481 HydrophobicContact CG-CG 4.31Å; F452-M481 HydrophobicContact CZ-CB 4.11Å
453	I	91.4	Very high	89.2	Confident	53 Å²	53	59.5 Å²	59.5	27%	0.272	32%	0.317	S	S	.	.	H	α-helix	trans	-59.5	-58.3	-178.6	-56.4	176.5	0	0	0	111.7	I391 L395 V450 V451 L455 F456 V457	I391-I453 HydrophobicContact CG2-CG1 4.41Å; L395-I453 HydrophobicContact CD1-CG1 4.05Å; L395-I453 HydrophobicContact CD2-CB 4.43Å; L395-I453 HydrophobicContact CD2-CG1 4.16Å; L395-I453 HydrophobicContact CG-CG1 4.33Å; V450-I453 HydrophobicContact CG2-CD1 3.98Å; V450-I453 WeakPolarHBondContact O-CB 3.33Å; V450-I453 PolarHBondContact O-N 3.1Å; V451-I453 PolarHBondContact O-N 3.49Å; I453-L455 VanDerWaalsContact C-N 3.29Å; I453-L455 PolarHBondContact O-N 3.04Å; I453-F456 PolarHBondContact O-N 3.19Å; I453-V457 VanDerWaalsContact O-CG2 3.3Å; I453-V457 WeakPolarHBondContact O-CG2 3.46Å; I453-V457 PolarHBondContact O-N 3.31Å
454	P	91	Very high	87.8	Confident	65 Å²	65	63.9 Å²	63.9	42%	0.422	35%	0.35	S	S	.	.	H	α-helix	trans	-63.3	-32.1	176.5	24.2	-33.5	0	0	0	113.2	V450 V451 V457 M458	V450-P454 VanDerWaalsContact O-CD 3.28Å; V450-P454 WeakPolarHBondContact O-CD 3.42Å; V451-P454 VanDerWaalsContact O-CD 3.26Å; V451-P454 WeakPolarHBondContact O-CD 3.43Å; V451-P454 WeakPolarHBondContact O-CG 3.4Å; P454-V457 PolarHBondContact O-N 3.14Å; P454-M458 VanDerWaalsContact O-CG 3.3Å; P454-M458 WeakPolarHBondContact O-CG 3.18Å; P454-M458 PolarHBondContact O-N 3.46Å
455	L	91.8	Very high	86.6	Confident	48 Å²	48	60.6 Å²	60.6	25%	0.251	35%	0.347	S	S	.	.	H	α-helix	trans	-63.6	-45	177.5	-70.7	174.8	0	0	0	112.6	V451 F452 I453 M458 C459 F477	V451-L455 HydrophobicContact CG1-CD1 3.99Å; V451-L455 HydrophobicContact CG1-CG 4.36Å; V451-L455 VanDerWaalsContact O-CG 3.3Å; V451-L455 WeakPolarHBondContact O-CG 3.48Å; V451-L455 PolarHBondContact O-N 3.27Å; F452-L455 HydrophobicContact CD1-CD1 4.44Å; F452-L455 PolarHBondContact O-N 2.73Å; I453-L455 VanDerWaalsContact C-N 3.29Å; I453-L455 PolarHBondContact O-N 3.04Å; L455-M458 PolarHBondContact O-N 2.92Å; L455-C459 PolarHBondContact O-N 3.44Å; L455-C459 PolarHBondContact O-SG 3.39Å; L455-C459 VanDerWaalsContact O-SG 3.33Å; L455-F477 HydrophobicContact CB-CD2 3.95Å; L455-F477 HydrophobicContact CB-CE2 3.87Å; L455-F477 HydrophobicContact CB-CG 4.32Å; L455-F477 HydrophobicContact CB-CZ 4.19Å; L455-F477 HydrophobicContact CD1-CD1 4.24Å; L455-F477 HydrophobicContact CD1-CE1 4.16Å; L455-F477 HydrophobicContact CD1-CZ 4.5Å; L455-F477 HydrophobicContact CD2-CE1 4.25Å; L455-F477 HydrophobicContact CD2-CE2 4.32Å; L455-F477 HydrophobicContact CD2-CZ 3.88Å; L455-F477 HydrophobicContact CG-CZ 4.42Å
456	F	88.2	Confident	85.8	Confident	0 Å²	0	58.6 Å²	58.6	0%	0	34%	0.342	C	S	.	.	H	α-helix	trans	-70.8	-35.8	174.3	-80.3	-73.1	0	0	0	112.4	L395 L399 E400 I403 F452 I453 M458 C459 V460 F477 M481	L395-F456 HydrophobicContact CD1-CD2 3.95Å; L395-F456 HydrophobicContact CD1-CE2 4.38Å; L395-F456 HydrophobicContact CD2-CB 4.28Å; L395-F456 HydrophobicContact CD2-CD2 4.38Å; L399-F456 HydrophobicContact CD2-CB 3.69Å; E400-F456 HydrophobicContact CG-CD1 4.36Å; E400-F456 HydrophobicContact CG-CE1 3.86Å; E400-F456 HydrophobicContact CG-CZ 4.22Å; E400-F456 WeakPolarHBondContact OE1-CE1 3.29Å; E400-F456 WeakPolarHBondContact OE1-CZ 3.46Å; I403-F456 HydrophobicContact CD1-CD1 3.88Å; I403-F456 HydrophobicContact CD1-CE1 4.34Å; F452-F456 HydrophobicContact CB-CD2 4.24Å; F452-F456 HydrophobicContact CB-CE2 4.33Å; F452-F456 VanDerWaalsContact O-CD2 3.29Å; F452-F456 WeakPolarHBondContact O-CD2 3.43Å; F452-F456 PolarHBondContact O-N 3.28Å; I453-F456 PolarHBondContact O-N 3.19Å; F456-M458 VanDerWaalsContact C-N 3.29Å; F456-M458 PolarHBondContact O-N 3.28Å; F456-C459 WeakPolarHBondContact O-CA 3.48Å; F456-C459 WeakPolarHBondContact O-CB 3.28Å; F456-C459 PolarHBondContact O-N 3.18Å; F456-V460 PolarHBondContact O-N 3.22Å; F456-F477 HydrophobicContact CE1-CB 4.01Å; F456-F477 HydrophobicContact CE2-CB 3.93Å; F456-F477 HydrophobicContact CZ-CB 3.67Å; F456-M481 HydrophobicContact CE2-CB 4.46Å; F456-M481 HydrophobicContact CE2-CE 3.88Å; F456-M481 HydrophobicContact CE2-SD 3.77Å; F456-M481 HydrophobicContact CZ-CE 3.99Å; F456-M481 HydrophobicContact CZ-SD 4.46Å
457	V	85.9	Confident	84.9	Confident	66 Å²	66	65 Å²	65	40%	0.4	37%	0.373	S	S	.	.	H	α-helix	trans	-60.6	-38.5	173.1	170.5	0	0	0	0	111.3	L399 I453 P454 C459 V460 Y461	L399-V457 HydrophobicContact CD2-CG2 4.43Å; I453-V457 VanDerWaalsContact O-CG2 3.3Å; I453-V457 WeakPolarHBondContact O-CG2 3.46Å; I453-V457 PolarHBondContact O-N 3.31Å; P454-V457 PolarHBondContact O-N 3.14Å; V457-C459 PolarHBondContact O-N 3.11Å; V457-V460 PolarHBondContact O-N 2.97Å; V457-Y461 WeakPolarHBondContact O-CB 3.21Å; V457-Y461 PolarHBondContact O-N 2.81Å
458	M	86.2	Confident	84.2	Confident	78 Å²	78	64.1 Å²	64.1	38%	0.384	36%	0.364	S	S	.	.	H	α-helix	trans	-66.8	-19	173.5	-72.1	175.2	-176.1	0	0	114.2	P454 L455 F456 M467 L468	P454-M458 VanDerWaalsContact O-CG 3.3Å; P454-M458 WeakPolarHBondContact O-CG 3.18Å; P454-M458 PolarHBondContact O-N 3.46Å; L455-M458 PolarHBondContact O-N 2.92Å; F456-M458 VanDerWaalsContact C-N 3.29Å; F456-M458 PolarHBondContact O-N 3.28Å; M458-M467 HydrophobicContact CB-CB 4.47Å; M458-M467 HydrophobicContact CG-SD 4.35Å; M458-M467 PolarHBondContact O-N 3.19Å; M458-L468 HydrophobicContact CB-CD1 4.09Å; M458-L468 HydrophobicContact CB-CG 4.35Å; M458-L468 PolarHBondContact O-N 3.3Å; M458-L468 VanDerWaalsContact O-N 3.13Å
459	C	83.4	Confident	83.2	Confident	9 Å²	9	63.6 Å²	63.6	6%	0.061	37%	0.368	C	S	.	.	H	α-helix	trans	-82.1	-15.5	171.9	-62.1	0	0	0	0	113.1	L455 F456 V457 P466 P474	L455-C459 PolarHBondContact O-N 3.44Å; L455-C459 PolarHBondContact O-SG 3.39Å; L455-C459 VanDerWaalsContact O-SG 3.33Å; F456-C459 WeakPolarHBondContact O-CA 3.48Å; F456-C459 WeakPolarHBondContact O-CB 3.28Å; F456-C459 PolarHBondContact O-N 3.18Å; V457-C459 PolarHBondContact O-N 3.11Å; C459-P466 WeakPolarHBondContact O-CB 3.28Å; C459-P474 HydrophobicContact CB-CG 4.08Å
460	V	79.1	Confident	82.7	Confident	39 Å²	39	69 Å²	69	24%	0.236	39%	0.393	C	S	.	.	H	α-helix	trans	-110.8	-35	-176.8	176.6	0	0	0	0	112.2	L399 I403 F456 V457 P462 V463	L399-V460 HydrophobicContact CD1-CG2 4.07Å; L399-V460 HydrophobicContact CG-CG2 4.47Å; I403-V460 HydrophobicContact CD1-CG2 4.42Å; I403-V460 HydrophobicContact CG1-CG2 3.84Å; F456-V460 PolarHBondContact O-N 3.22Å; V457-V460 PolarHBondContact O-N 2.97Å; V460-P462 CarbonylContact O-C 3.57Å; V460-V463 PolarHBondContact O-N 3.47Å
461	Y	74.3	Confident	82.3	Confident	159 Å²	159	66.7 Å²	66.7	62%	0.624	38%	0.38	S	S	*	.	S	Bend	trans	-110.3	140.9	-171.6	-168.3	-90.4	0	0	0	112.6	V457	V457-Y461 WeakPolarHBondContact O-CB 3.21Å; V457-Y461 PolarHBondContact O-N 2.81Å
462	P	70.6	Confident	81.9	Confident	45 Å²	45	65.8 Å²	65.8	29%	0.292	38%	0.38	S	S	.	.	S	Bend	cis	-72.6	144.8	-11.9	30.5	-34.2	0	0	0	111.7	V460 S464 A465 P466	V460-P462 CarbonylContact O-C 3.57Å; P462-S464 PolarHBondContact O-N 3.11Å; P462-A465 WeakPolarHBondContact CD-O 3.32Å; P462-A465 WeakPolarHBondContact CG-O 3.48Å; P462-A465 CarbonylContact O-C 3.56Å; P462-A465 PolarHBondContact O-N 3.23Å; P462-P466 WeakPolarHBondContact O-CD 3.35Å; P462-P466 VanDerWaalsContact O-N 3.08Å
463	V	70.3	Confident	81.8	Confident	126 Å²	126	69.9 Å²	69.9	76%	0.764	39%	0.394	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.5	-29.7	-172.4	177.2	0	0	0	0	113.2	V460	V460-V463 PolarHBondContact O-N 3.47Å
464	S	67.1	Low	81.7	Confident	118 Å²	118	67.5 Å²	67.5	83%	0.825	38%	0.383	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.8	-27.3	177.6	48.2	0	0	0	0	114.2	P462	P462-S464 PolarHBondContact O-N 3.11Å
465	A	71.9	Confident	81.7	Confident	64 Å²	64	66 Å²	66	53%	0.529	37%	0.373	S	S	.	.	S	Bend	trans	-158.9	80.2	-178.3	0	0	0	0	0	110.4	P462 M467	P462-A465 WeakPolarHBondContact CD-O 3.32Å; P462-A465 WeakPolarHBondContact CG-O 3.48Å; P462-A465 CarbonylContact O-C 3.56Å; P462-A465 PolarHBondContact O-N 3.23Å; A465-M467 PolarHBondContact O-N 3Å
466	P	78.8	Confident	81.9	Confident	32 Å²	32	67.5 Å²	67.5	21%	0.208	38%	0.381	C	S	.	.			trans	-59.1	137.7	-178.4	-24.1	33.6	0	0	0	111.5	C459 P462 L468 S469	C459-P466 WeakPolarHBondContact O-CB 3.28Å; P462-P466 WeakPolarHBondContact O-CD 3.35Å; P462-P466 VanDerWaalsContact O-N 3.08Å; P466-L468 PolarHBondContact O-N 3.04Å; P466-S469 WeakPolarHBondContact O-CB 3.44Å; P466-S469 PolarHBondContact O-N 3.13Å; P466-S469 PolarHBondContact O-OG 3.49Å
467	M	77.9	Confident	82.2	Confident	135 Å²	135	68.2 Å²	68.2	67%	0.665	38%	0.384	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.3	-34.7	-179.2	-70.3	-178	64.5	0	0	112.1	M458 A465	M458-M467 HydrophobicContact CB-CB 4.47Å; M458-M467 HydrophobicContact CG-SD 4.35Å; M458-M467 PolarHBondContact O-N 3.19Å; A465-M467 PolarHBondContact O-N 3Å
468	L	82.2	Confident	82.6	Confident	40 Å²	40	65 Å²	65	21%	0.209	37%	0.365	C	S	.	.	T	Hydrogen-bonded Turn	trans	-112.7	67.2	176.4	-63.1	178.1	0	0	0	110.8	M458 P466 H470 W473 F477	M458-L468 HydrophobicContact CB-CD1 4.09Å; M458-L468 HydrophobicContact CB-CG 4.35Å; M458-L468 PolarHBondContact O-N 3.3Å; M458-L468 VanDerWaalsContact O-N 3.13Å; P466-L468 PolarHBondContact O-N 3.04Å; L468-H470 VanDerWaalsContact C-N 3.33Å; L468-H470 PolarHBondContact O-N 3.47Å; L468-W473 HydrophobicContact CB-CB 4.01Å; L468-W473 HydrophobicContact CB-CG 3.97Å; L468-W473 HydrophobicContact CD1-CB 4.49Å; L468-W473 HydrophobicContact CD1-CG 4.47Å; L468-W473 HydrophobicContact CD2-CD2 4.2Å; L468-W473 HydrophobicContact CD2-CG 4.23Å; L468-W473 HydrophobicContact CG-CG 4.45Å; L468-F477 HydrophobicContact CD1-CE2 3.58Å; L468-F477 HydrophobicContact CD1-CZ 3.75Å
469	S	75.9	Confident	83.1	Confident	77 Å²	77	65 Å²	65	54%	0.538	37%	0.366	S	S	.	.			trans	-75.5	-12.6	-170.3	4.4	0	0	0	0	115.3	N405 P466	N405-S469 PolarHBondContact ND2-O 3.31Å; P466-S469 WeakPolarHBondContact O-CB 3.44Å; P466-S469 PolarHBondContact O-N 3.13Å; P466-S469 PolarHBondContact O-OG 3.49Å
470	H	86.1	Confident	83.7	Confident	119 Å²	119	68.4 Å²	68.4	55%	0.551	38%	0.383	S	S	*	.	S	Bend	trans	-78.7	130.8	178.5	-170.2	-94.4	0	0	0	111.1	L468 A472 W473	L468-H470 VanDerWaalsContact C-N 3.33Å; L468-H470 PolarHBondContact O-N 3.47Å; H470-A472 VanDerWaalsContact ND1-CB 3.29Å; H470-A472 WeakPolarHBondContact ND1-CB 3.34Å; H470-A472 PolarHBondContact ND1-N 3.22Å; H470-A472 PolarHBondContact O-N 3.02Å; H470-W473 PolarHBondContact O-N 3Å
471	P	85.1	Confident	84.5	Confident	31 Å²	31	66.5 Å²	66.5	20%	0.201	37%	0.372	C	S	.	.	T	Hydrogen-bonded Turn	trans	-65.4	-15.7	-170.8	26.6	-34.3	0	0	0	114.2	N405 L408 L412 W473 P474 C475	N405-P471 WeakPolarHBondContact ND2-CD 3.45Å; L408-P471 HydrophobicContact CD1-CB 4.14Å; L408-P471 HydrophobicContact CD1-CG 4.49Å; L412-P471 HydrophobicContact CD1-CB 4.1Å; L412-P471 HydrophobicContact CD2-CB 4.32Å; P471-W473 VanDerWaalsContact C-N 3.29Å; P471-W473 PolarHBondContact O-N 3.47Å; P471-P474 WeakPolarHBondContact O-CD 2.97Å; P471-C475 PolarHBondContact O-SG 3.39Å; P471-C475 VanDerWaalsContact O-SG 3.41Å
472	A	89.2	Confident	85.6	Confident	52 Å²	52	59 Å²	59	43%	0.43	34%	0.342	S	S	.	.	H	α-helix	trans	-66.3	-26.1	173.3	0	0	0	0	0	113.7	H470 C475 L476	H470-A472 VanDerWaalsContact ND1-CB 3.29Å; H470-A472 WeakPolarHBondContact ND1-CB 3.34Å; H470-A472 PolarHBondContact ND1-N 3.22Å; H470-A472 PolarHBondContact O-N 3.02Å; A472-C475 PolarHBondContact O-N 3.28Å; A472-L476 VanDerWaalsContact O-CB 3.24Å; A472-L476 WeakPolarHBondContact O-CB 3.29Å; A472-L476 PolarHBondContact O-N 3.44Å
473	W	91	Very high	86.9	Confident	111 Å²	111	58.7 Å²	58.7	42%	0.42	34%	0.34	S	S	.	.	H	α-helix	trans	-67.2	-52.4	-179.1	-66.7	115.3	0	0	0	112.6	L468 H470 P471 C475 L476 F477	L468-W473 HydrophobicContact CB-CB 4.01Å; L468-W473 HydrophobicContact CB-CG 3.97Å; L468-W473 HydrophobicContact CD1-CB 4.49Å; L468-W473 HydrophobicContact CD1-CG 4.47Å; L468-W473 HydrophobicContact CD2-CD2 4.2Å; L468-W473 HydrophobicContact CD2-CG 4.23Å; L468-W473 HydrophobicContact CG-CG 4.45Å; H470-W473 PolarHBondContact O-N 3Å; P471-W473 VanDerWaalsContact C-N 3.29Å; P471-W473 PolarHBondContact O-N 3.47Å; W473-C475 VanDerWaalsContact C-N 3.32Å; W473-C475 PolarHBondContact O-N 2.96Å; W473-L476 HydrophobicContact CE3-CD2 4.2Å; W473-L476 HydrophobicContact CZ3-CD2 4.15Å; W473-L476 PolarHBondContact O-N 2.89Å; W473-F477 HydrophobicContact CB-CE2 4.19Å; W473-F477 HydrophobicContact CE3-CE1 4.12Å; W473-F477 AromaticContact CE3-CZ 3.83Å; W473-F477 HydrophobicContact CE3-CZ 3.83Å; W473-F477 WeakPolarHBondContact O-CD2 3.06Å; W473-F477 VanDerWaalsContact O-CG 3.3Å; W473-F477 WeakPolarHBondContact O-CG 3.48Å; W473-F477 PolarHBondContact O-N 2.93Å
474	P	89.9	Confident	88.2	Confident	4 Å²	4	54.4 Å²	54.4	3%	0.026	31%	0.314	C	S	.	.	H	α-helix	trans	-52.5	-46.4	170.4	-27.7	32.8	0	0	0	113.5	I403 I416 C459 P471 L476 F477 S478	I403-P474 HydrophobicContact CD1-CB 4.09Å; I403-P474 HydrophobicContact CD1-CG 4.38Å; I403-P474 HydrophobicContact CG2-CB 4.07Å; I403-P474 HydrophobicContact CG2-CG 3.67Å; I416-P474 HydrophobicContact CD1-CB 3.55Å; I416-P474 HydrophobicContact CG1-CB 4.14Å; C459-P474 HydrophobicContact CB-CG 4.08Å; P471-P474 WeakPolarHBondContact O-CD 2.97Å; P474-L476 PolarHBondContact O-N 3.44Å; P474-F477 PolarHBondContact O-N 3.43Å; P474-S478 WeakPolarHBondContact O-CB 3.28Å; P474-S478 PolarHBondContact O-N 3.07Å
475	C	91.9	Very high	89.6	Confident	33 Å²	33	49 Å²	49	22%	0.223	28%	0.275	C	S	.	.	H	α-helix	trans	-64.5	-39.9	-179.8	-62.7	0	0	0	0	112.5	P471 A472 W473 L479	P471-C475 PolarHBondContact O-SG 3.39Å; P471-C475 VanDerWaalsContact O-SG 3.41Å; A472-C475 PolarHBondContact O-N 3.28Å; W473-C475 VanDerWaalsContact C-N 3.32Å; W473-C475 PolarHBondContact O-N 2.96Å; C475-L479 VanDerWaalsContact O-CB 3.28Å; C475-L479 WeakPolarHBondContact O-CB 3.1Å; C475-L479 PolarHBondContact O-N 3.15Å
476	L	94.8	Very high	90.7	Very high	79 Å²	79	45.9 Å²	45.9	41%	0.414	25%	0.25	S	S	.	.	H	α-helix	trans	-65.9	-45.4	176.5	177	61.9	0	0	0	111.6	A472 W473 P474 L479 L480	A472-L476 VanDerWaalsContact O-CB 3.24Å; A472-L476 WeakPolarHBondContact O-CB 3.29Å; A472-L476 PolarHBondContact O-N 3.44Å; W473-L476 HydrophobicContact CE3-CD2 4.2Å; W473-L476 HydrophobicContact CZ3-CD2 4.15Å; W473-L476 PolarHBondContact O-N 2.89Å; P474-L476 PolarHBondContact O-N 3.44Å; L476-L479 PolarHBondContact O-N 2.93Å; L476-L480 HydrophobicContact CD1-CD1 4.2Å; L476-L480 HydrophobicContact CD1-CG 4.33Å; L476-L480 HydrophobicContact CG-CD1 4.21Å; L476-L480 WeakPolarHBondContact O-CB 3.29Å; L476-L480 WeakPolarHBondContact O-CG 3.49Å; L476-L480 PolarHBondContact O-N 3.37Å
477	F	94.7	Very high	91.5	Very high	15 Å²	15	46.1 Å²	46.1	7%	0.066	25%	0.247	C	C	.	.	H	α-helix	trans	-67.1	-38.2	178.3	-59.8	-28.5	0	0	0	111.8	L455 F456 L468 W473 P474 L480 M481	L455-F477 HydrophobicContact CB-CD2 3.95Å; L455-F477 HydrophobicContact CB-CE2 3.87Å; L455-F477 HydrophobicContact CB-CG 4.32Å; L455-F477 HydrophobicContact CB-CZ 4.19Å; L455-F477 HydrophobicContact CD1-CD1 4.24Å; L455-F477 HydrophobicContact CD1-CE1 4.16Å; L455-F477 HydrophobicContact CD1-CZ 4.5Å; L455-F477 HydrophobicContact CD2-CE1 4.25Å; L455-F477 HydrophobicContact CD2-CE2 4.32Å; L455-F477 HydrophobicContact CD2-CZ 3.88Å; L455-F477 HydrophobicContact CG-CZ 4.42Å; F456-F477 HydrophobicContact CE1-CB 4.01Å; F456-F477 HydrophobicContact CE2-CB 3.93Å; F456-F477 HydrophobicContact CZ-CB 3.67Å; L468-F477 HydrophobicContact CD1-CE2 3.58Å; L468-F477 HydrophobicContact CD1-CZ 3.75Å; W473-F477 HydrophobicContact CB-CE2 4.19Å; W473-F477 HydrophobicContact CE3-CE1 4.12Å; W473-F477 AromaticContact CE3-CZ 3.83Å; W473-F477 HydrophobicContact CE3-CZ 3.83Å; W473-F477 WeakPolarHBondContact O-CD2 3.06Å; W473-F477 VanDerWaalsContact O-CG 3.3Å; W473-F477 WeakPolarHBondContact O-CG 3.48Å; W473-F477 PolarHBondContact O-N 2.93Å; P474-F477 PolarHBondContact O-N 3.43Å; F477-L480 PolarHBondContact O-N 3.18Å; F477-M481 WeakPolarHBondContact O-CB 3.46Å; F477-M481 PolarHBondContact O-N 2.82Å
478	S	94.4	Very high	92.4	Very high	0 Å²	0	40.7 Å²	40.7	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-65.8	-41.9	175.4	-165.1	0	0	0	0	112	E400 I416 F420 P474 M481 G482	E400-S478 WeakPolarHBondContact OE1-CB 3.28Å; E400-S478 PolarHBondContact OE1-OG 2.91Å; E400-S478 PolarHBondContact OE2-OG 2.74Å; I416-S478 WeakPolarHBondContact CG2-OG 3.19Å; I416-S478 PolarHBondContact O-OG 3.35Å; F420-S478 WeakPolarHBondContact CB-OG 3.4Å; P474-S478 WeakPolarHBondContact O-CB 3.28Å; P474-S478 PolarHBondContact O-N 3.07Å; S478-M481 PolarHBondContact O-N 3.24Å; S478-G482 PolarHBondContact O-N 3.41Å
479	L	96.4	Very high	92.9	Very high	78 Å²	78	38.8 Å²	38.8	41%	0.408	21%	0.21	S	C	.	.	H	α-helix	trans	-60	-48.3	172.4	-178.5	146	0	0	0	112	T419 S423 C475 L476 G482 V483	T419-L479 HydrophobicContact CG2-CB 3.74Å; T419-L479 HydrophobicContact CG2-CD1 4.39Å; S423-L479 WeakPolarHBondContact CB-O 3.36Å; S423-L479 PolarHBondContact OG-O 2.68Å; C475-L479 VanDerWaalsContact O-CB 3.28Å; C475-L479 WeakPolarHBondContact O-CB 3.1Å; C475-L479 PolarHBondContact O-N 3.15Å; L476-L479 PolarHBondContact O-N 2.93Å; L479-G482 PolarHBondContact O-N 3.11Å; L479-V483 WeakPolarHBondContact O-CG2 3.45Å; L479-V483 PolarHBondContact O-N 2.86Å
480	L	96.9	Very high	93.8	Very high	79 Å²	79	35.1 Å²	35.1	41%	0.414	18%	0.184	S	C	.	.	H	α-helix	trans	-65.1	-42.8	178.4	-71.2	172.9	0	0	0	111.4	F452 L476 F477 G482 T484	F452-L480 HydrophobicContact CE1-CB 3.9Å; F452-L480 HydrophobicContact CZ-CB 4.1Å; L476-L480 HydrophobicContact CD1-CD1 4.2Å; L476-L480 HydrophobicContact CD1-CG 4.33Å; L476-L480 HydrophobicContact CG-CD1 4.21Å; L476-L480 WeakPolarHBondContact O-CB 3.29Å; L476-L480 WeakPolarHBondContact O-CG 3.49Å; L476-L480 PolarHBondContact O-N 3.37Å; F477-L480 PolarHBondContact O-N 3.18Å; L480-G482 VanDerWaalsContact C-N 3.35Å; L480-T484 WeakPolarHBondContact O-CB 3.36Å; L480-T484 WeakPolarHBondContact O-CG2 3.47Å; L480-T484 PolarHBondContact O-N 3.28Å; L480-T484 VanDerWaalsContact O-N 3.13Å; L480-T484 PolarHBondContact O-OG1 2.89Å
481	M	96.1	Very high	94.2	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-63.3	-40.1	178.4	-176.2	175.8	65.9	0	0	111.6	L395 F396 E400 F420 R449 F452 F456 F477 S478 T484 N485	L395-M481 HydrophobicContact CB-CE 4.34Å; L395-M481 HydrophobicContact CB-SD 4.05Å; L395-M481 HydrophobicContact CD1-SD 3.68Å; F396-M481 HydrophobicContact CB-CE 4.04Å; E400-M481 WeakPolarHBondContact OE1-CE 3.27Å; F420-M481 HydrophobicContact CD2-CE 3.81Å; F420-M481 HydrophobicContact CE2-CE 3.92Å; F420-M481 HydrophobicContact CE2-CG 4.27Å; R449-M481 PolarHBondContact NH1-O 3.5Å; R449-M481 PolarHBondContact NH2-O 3.12Å; R449-M481 VanDerWaalsContact NH2-O 3.07Å; F452-M481 HydrophobicContact CB-SD 4.48Å; F452-M481 HydrophobicContact CD1-CB 4.16Å; F452-M481 HydrophobicContact CD2-CB 4.18Å; F452-M481 HydrophobicContact CD2-CG 4.06Å; F452-M481 HydrophobicContact CE1-CB 4.12Å; F452-M481 HydrophobicContact CE2-CB 4.14Å; F452-M481 HydrophobicContact CE2-CG 4.32Å; F452-M481 HydrophobicContact CG-CB 4.22Å; F452-M481 HydrophobicContact CG-CG 4.31Å; F452-M481 HydrophobicContact CZ-CB 4.11Å; F456-M481 HydrophobicContact CE2-CB 4.46Å; F456-M481 HydrophobicContact CE2-CE 3.88Å; F456-M481 HydrophobicContact CE2-SD 3.77Å; F456-M481 HydrophobicContact CZ-CE 3.99Å; F456-M481 HydrophobicContact CZ-SD 4.46Å; F477-M481 WeakPolarHBondContact O-CB 3.46Å; F477-M481 PolarHBondContact O-N 2.82Å; S478-M481 PolarHBondContact O-N 3.24Å; M481-T484 PolarHBondContact O-OG1 2.93Å; M481-N485 WeakPolarHBondContact O-CB 3.44Å; M481-N485 PolarHBondContact O-N 3.19Å
482	G	96.6	Very high	94.7	Very high	0 Å²	0	28.2 Å²	28.2	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-68.4	-54.7	177.1	0	0	0	0	0	112.8	S423 D424 S478 L479 L480 T484 N485 G486	S423-G482 WeakPolarHBondContact OG-CA 3.49Å; D424-G482 VanDerWaalsContact CA-O 3.32Å; D424-G482 WeakPolarHBondContact CA-O 3.33Å; S478-G482 PolarHBondContact O-N 3.41Å; L479-G482 PolarHBondContact O-N 3.11Å; L480-G482 VanDerWaalsContact C-N 3.35Å; G482-T484 PolarHBondContact O-N 3.39Å; G482-N485 WeakPolarHBondContact O-CA 3.39Å; G482-N485 WeakPolarHBondContact O-CB 3.4Å; G482-N485 PolarHBondContact O-N 3.25Å; G482-G486 PolarHBondContact O-N 3.23Å
483	V	97.4	Very high	94.9	Very high	40 Å²	40	26 Å²	26	24%	0.242	13%	0.131	C	C	.	.	H	α-helix	trans	-52.3	-45.9	176.3	175.2	0	0	0	0	110.9	S423 G427 L430 L479 Y487	S423-V483 VanDerWaalsContact O-CA 3.31Å; S423-V483 WeakPolarHBondContact O-CA 3.48Å; S423-V483 PolarHBondContact O-N 3.14Å; G427-V483 WeakPolarHBondContact CA-O 3.26Å; L430-V483 HydrophobicContact CD1-CG1 4.09Å; L479-V483 WeakPolarHBondContact O-CG2 3.45Å; L479-V483 PolarHBondContact O-N 2.86Å; V483-Y487 WeakPolarHBondContact O-CB 3.37Å; V483-Y487 PolarHBondContact O-N 3.5Å; V483-Y487 VanDerWaalsContact O-N 3.08Å
484	T	97.1	Very high	95	Very high	36 Å²	36	21.4 Å²	21.4	22%	0.221	11%	0.114	C	C	.	.	H	α-helix	trans	-74	-25.2	179.8	54.6	0	0	0	0	113	R449 L480 M481 G482 F488	R449-T484 VanDerWaalsContact NH1-CB 3.26Å; R449-T484 PolarHBondContact NH1-O 2.7Å; R449-T484 PolarHBondContact NH1-OG1 2.78Å; L480-T484 WeakPolarHBondContact O-CB 3.36Å; L480-T484 WeakPolarHBondContact O-CG2 3.47Å; L480-T484 PolarHBondContact O-N 3.28Å; L480-T484 VanDerWaalsContact O-N 3.13Å; L480-T484 PolarHBondContact O-OG1 2.89Å; M481-T484 PolarHBondContact O-OG1 2.93Å; G482-T484 PolarHBondContact O-N 3.39Å; T484-F488 HydrophobicContact CG2-CE2 4.28Å; T484-F488 WeakPolarHBondContact O-CB 3.06Å; T484-F488 VanDerWaalsContact O-CD2 3.3Å; T484-F488 WeakPolarHBondContact O-CD2 3.47Å; T484-F488 PolarHBondContact O-N 3.13Å
485	N	96.6	Very high	95.2	Very high	3 Å²	3	21.8 Å²	21.8	2%	0.016	12%	0.115	C	C	.	.	H	α-helix	trans	-69.4	-48.8	172.3	-171.7	76.6	0	0	0	110.4	T392 F420 D424 R449 M481 G482 Y487 G489	T392-N485 WeakPolarHBondContact CB-OD1 3.38Å; T392-N485 PolarHBondContact OG1-OD1 3.39Å; F420-N485 HydrophobicContact CE2-CB 4.31Å; F420-N485 HydrophobicContact CZ-CB 4.2Å; D424-N485 WeakPolarHBondContact OD1-CB 3.45Å; D424-N485 PolarHBondContact OD1-ND2 3.3Å; R449-N485 VanDerWaalsContact NH1-N 3.16Å; M481-N485 WeakPolarHBondContact O-CB 3.44Å; M481-N485 PolarHBondContact O-N 3.19Å; G482-N485 WeakPolarHBondContact O-CA 3.39Å; G482-N485 WeakPolarHBondContact O-CB 3.4Å; G482-N485 PolarHBondContact O-N 3.25Å; N485-Y487 VanDerWaalsContact C-N 3.31Å; N485-Y487 PolarHBondContact O-N 3.31Å; N485-G489 VanDerWaalsContact O-CA 3.23Å; N485-G489 WeakPolarHBondContact O-CA 3.28Å; N485-G489 PolarHBondContact O-N 3.23Å
486	G	95.6	Very high	95.2	Very high	0 Å²	0	20.2 Å²	20.2	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-60.2	-43.8	179	0	0	0	0	0	111.3	D424 G427 G482 S490	D424-G486 VanDerWaalsContact OD1-CA 3.24Å; D424-G486 WeakPolarHBondContact OD1-CA 3.48Å; D424-G486 PolarHBondContact OD1-N 2.9Å; G427-G486 VanDerWaalsContact C-C 3.48Å; G427-G486 CarbonylContact O-C 3.54Å; G482-G486 PolarHBondContact O-N 3.23Å; G486-S490 WeakPolarHBondContact O-CB 3.35Å; G486-S490 PolarHBondContact O-N 2.84Å; G486-S490 VanDerWaalsContact O-N 3.15Å; G486-S490 PolarHBondContact O-OG 3.15Å
487	Y	95.9	Very high	94.9	Very high	36 Å²	36	17 Å²	17	14%	0.141	9%	0.089	C	C	.	.	H	α-helix	trans	-70	-60.8	179.8	-165.4	-96.6	0	0	0	112.9	G427 L430 A431 W437 V483 N485 G489 S490 V491	G427-Y487 WeakPolarHBondContact O-CA 3.41Å; G427-Y487 PolarHBondContact O-N 3.02Å; L430-Y487 HydrophobicContact CB-CD2 3.94Å; L430-Y487 HydrophobicContact CB-CE2 4.35Å; L430-Y487 WeakPolarHBondContact O-CE2 3.43Å; A431-Y487 HydrophobicContact CB-CD2 4.23Å; W437-Y487 AromaticContact CE2-CE1 3.92Å; W437-Y487 AromaticContact CZ2-CE1 4Å; W437-Y487 HydrophobicContact CZ2-CE1 4Å; W437-Y487 AromaticContact NE1-CE1 3.49Å; W437-Y487 AromaticContact NE1-CZ 3.6Å; W437-Y487 PolarHBondContact NE1-OH 2.82Å; V483-Y487 WeakPolarHBondContact O-CB 3.37Å; V483-Y487 PolarHBondContact O-N 3.5Å; V483-Y487 VanDerWaalsContact O-N 3.08Å; N485-Y487 VanDerWaalsContact C-N 3.31Å; N485-Y487 PolarHBondContact O-N 3.31Å; Y487-G489 VanDerWaalsContact C-N 3.29Å; Y487-G489 PolarHBondContact O-N 2.95Å; Y487-S490 PolarHBondContact O-N 3.18Å; Y487-S490 VanDerWaalsContact O-N 3.17Å; Y487-V491 HydrophobicContact CD1-CG2 4.2Å; Y487-V491 HydrophobicContact CD2-CG2 4.31Å; Y487-V491 HydrophobicContact CE1-CG2 3.95Å; Y487-V491 HydrophobicContact CE2-CG2 4.07Å; Y487-V491 HydrophobicContact CG-CG2 4.38Å; Y487-V491 WeakPolarHBondContact O-CG2 3.48Å; Y487-V491 PolarHBondContact O-N 3.49Å
488	F	95.7	Very high	94.6	Very high	21 Å²	21	18.4 Å²	18.4	9%	0.092	11%	0.109	C	C	.	.	H	α-helix	trans	-74.8	-16.3	-176.7	-64.6	-63.8	0	0	0	113.7	T388 W437 L442 F445 T484 P492	T388-F488 HydrophobicContact CG2-CB 4.31Å; W437-F488 HydrophobicContact CH2-CE1 4.45Å; W437-F488 HydrophobicContact CZ2-CE1 4.44Å; L442-F488 HydrophobicContact CD2-CD1 3.88Å; L442-F488 HydrophobicContact CD2-CE1 4.26Å; F445-F488 HydrophobicContact CB-CD1 4.19Å; F445-F488 HydrophobicContact CB-CE1 3.57Å; F445-F488 HydrophobicContact CB-CE2 3.95Å; F445-F488 HydrophobicContact CB-CZ 3.43Å; F445-F488 VanDerWaalsContact CB-CZ 3.43Å; F445-F488 HydrophobicContact CD1-CZ 4.4Å; F445-F488 HydrophobicContact CD2-CE1 4.42Å; F445-F488 HydrophobicContact CD2-CZ 4.4Å; F445-F488 HydrophobicContact CG-CE1 4.17Å; F445-F488 AromaticContact CG-CZ 3.85Å; F445-F488 HydrophobicContact CG-CZ 3.85Å; T484-F488 HydrophobicContact CG2-CE2 4.28Å; T484-F488 WeakPolarHBondContact O-CB 3.06Å; T484-F488 VanDerWaalsContact O-CD2 3.3Å; T484-F488 WeakPolarHBondContact O-CD2 3.47Å; T484-F488 PolarHBondContact O-N 3.13Å; F488-P492 WeakPolarHBondContact O-CD 3.27Å; F488-P492 WeakPolarHBondContact O-CG 3.4Å
489	G	93.9	Very high	94.5	Very high	0 Å²	0	23.1 Å²	23.1	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-75.6	-36.9	167.6	0	0	0	0	0	112.2	I385 N485 Y487	I385-G489 VanDerWaalsContact CD1-O 3.26Å; I385-G489 WeakPolarHBondContact CD1-O 3.2Å; N485-G489 VanDerWaalsContact O-CA 3.23Å; N485-G489 WeakPolarHBondContact O-CA 3.28Å; N485-G489 PolarHBondContact O-N 3.23Å; Y487-G489 VanDerWaalsContact C-N 3.29Å; Y487-G489 PolarHBondContact O-N 2.95Å
490	S	94.8	Very high	94.2	Very high	0 Å²	0	19.8 Å²	19.8	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-88.4	-44.8	-174	-54.2	0	0	0	0	114.4	M232 K428 G486 Y487 P492 M493 I494	M232-S490 VanDerWaalsContact SD-CA 3.55Å; K428-S490 WeakPolarHBondContact CD-OG 3.48Å; K428-S490 VanDerWaalsContact CG-OG 3.31Å; K428-S490 WeakPolarHBondContact CG-OG 3.32Å; G486-S490 WeakPolarHBondContact O-CB 3.35Å; G486-S490 PolarHBondContact O-N 2.84Å; G486-S490 VanDerWaalsContact O-N 3.15Å; G486-S490 PolarHBondContact O-OG 3.15Å; Y487-S490 PolarHBondContact O-N 3.18Å; Y487-S490 VanDerWaalsContact O-N 3.17Å; S490-P492 VanDerWaalsContact C-CD 3.49Å; S490-M493 PolarHBondContact O-N 3.22Å; S490-M493 VanDerWaalsContact O-N 3.11Å; S490-I494 WeakPolarHBondContact O-CD1 3.41Å; S490-I494 VanDerWaalsContact O-CG1 3.27Å; S490-I494 WeakPolarHBondContact O-CG1 3.49Å; S490-I494 PolarHBondContact O-N 3.4Å
491	V	95.1	Very high	93.7	Very high	5 Å²	5	19.5 Å²	19.5	3%	0.03	12%	0.115	C	C	.	.	H	α-helix	trans	-55	-42.7	-176.2	174	0	0	0	0	113	A431 W437 L442 Y487 M493 I494 Q495	A431-V491 HydrophobicContact CB-CG2 3.85Å; W437-V491 HydrophobicContact CB-CG1 4.39Å; W437-V491 HydrophobicContact CG-CG1 4.26Å; L442-V491 HydrophobicContact CD1-CG1 4.1Å; L442-V491 HydrophobicContact CD2-CB 4.17Å; L442-V491 HydrophobicContact CD2-CG1 3.79Å; Y487-V491 HydrophobicContact CD1-CG2 4.2Å; Y487-V491 HydrophobicContact CD2-CG2 4.31Å; Y487-V491 HydrophobicContact CE1-CG2 3.95Å; Y487-V491 HydrophobicContact CE2-CG2 4.07Å; Y487-V491 HydrophobicContact CG-CG2 4.38Å; Y487-V491 WeakPolarHBondContact O-CG2 3.48Å; Y487-V491 PolarHBondContact O-N 3.49Å; V491-M493 PolarHBondContact O-N 3.42Å; V491-I494 PolarHBondContact O-N 3.27Å; V491-Q495 HydrophobicContact CG1-CG 4.26Å; V491-Q495 WeakPolarHBondContact O-CB 3.06Å; V491-Q495 WeakPolarHBondContact O-CG 3.46Å; V491-Q495 PolarHBondContact O-N 3.46Å
492	P	94.8	Very high	93.2	Very high	0 Å²	0	22.4 Å²	22.4	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-62.8	-42.3	177.4	-20.7	31.7	0	0	0	113.3	Y381 S384 I385 L442 F488 S490 Q495 A496 M512	Y381-P492 HydrophobicContact CD1-CB 4.22Å; S384-P492 WeakPolarHBondContact OG-CG 3.31Å; I385-P492 HydrophobicContact CB-CB 4.37Å; L442-P492 HydrophobicContact CD1-CG 4.2Å; F488-P492 WeakPolarHBondContact O-CD 3.27Å; F488-P492 WeakPolarHBondContact O-CG 3.4Å; S490-P492 VanDerWaalsContact C-CD 3.49Å; P492-Q495 PolarHBondContact O-N 2.81Å; P492-A496 WeakPolarHBondContact O-CB 3.12Å; P492-A496 PolarHBondContact O-N 2.95Å; P492-M512 HydrophobicContact CB-CE 3.9Å
493	M	93.2	Very high	92.6	Very high	7 Å²	7	29.6 Å²	29.6	3%	0.034	17%	0.168	C	C	.	.	H	α-helix	trans	-65.1	-40.9	178.4	-175.2	67.6	82.6	0	0	111.4	Y217 T228 M232 I385 S490 V491 M512	Y217-M493 HydrophobicContact CD1-CE 4.04Å; Y217-M493 HydrophobicContact CD1-CG 3.75Å; Y217-M493 HydrophobicContact CD1-SD 3.71Å; Y217-M493 HydrophobicContact CD2-CE 4.36Å; Y217-M493 HydrophobicContact CE1-CE 4.25Å; Y217-M493 HydrophobicContact CE1-CG 3.77Å; Y217-M493 HydrophobicContact CE1-SD 4.23Å; Y217-M493 HydrophobicContact CG-CE 4.12Å; Y217-M493 HydrophobicContact CG-SD 4.12Å; T228-M493 HydrophobicContact CG2-CG 3.82Å; M232-M493 HydrophobicContact CE-CB 4.11Å; M232-M493 HydrophobicContact CE-CG 4.38Å; M232-M493 HydrophobicContact SD-CB 3.51Å; M232-M493 VanDerWaalsContact SD-CB 3.51Å; M232-M493 HydrophobicContact SD-CG 3.64Å; I385-M493 HydrophobicContact CD1-CB 4.23Å; I385-M493 HydrophobicContact CD1-CE 3.98Å; S490-M493 PolarHBondContact O-N 3.22Å; S490-M493 VanDerWaalsContact O-N 3.11Å; V491-M493 PolarHBondContact O-N 3.42Å; M493-M512 HydrophobicContact CE-CB 3.92Å; M493-M512 HydrophobicContact SD-CB 3.49Å; M493-M512 WeakPolarHBondContact SD-CB 3.37Å; M493-M512 HydrophobicContact SD-CG 4.32Å
494	I	92.9	Very high	92.1	Very high	13 Å²	13	29.3 Å²	29.3	7%	0.067	16%	0.164	C	C	.	.	H	α-helix	trans	-65.6	-39.9	177.2	-64.8	160.6	0	0	0	111.4	K225 T228 Q229 A431 S490 V491	K225-I494 HydrophobicContact CB-CG2 3.76Å; K225-I494 HydrophobicContact CD-CG2 4.3Å; K225-I494 HydrophobicContact CG-CG2 4.1Å; T228-I494 HydrophobicContact CG2-CG1 4.16Å; Q229-I494 HydrophobicContact CB-CD1 3.61Å; Q229-I494 HydrophobicContact CB-CG1 4.05Å; Q229-I494 HydrophobicContact CG-CD1 3.82Å; A431-I494 HydrophobicContact CB-CD1 4.06Å; S490-I494 WeakPolarHBondContact O-CD1 3.41Å; S490-I494 VanDerWaalsContact O-CG1 3.27Å; S490-I494 WeakPolarHBondContact O-CG1 3.49Å; S490-I494 PolarHBondContact O-N 3.4Å; V491-I494 PolarHBondContact O-N 3.27Å
495	Q	93.5	Very high	91.6	Very high	12 Å²	12	31.3 Å²	31.3	6%	0.056	17%	0.167	C	C	.	.	H	α-helix	trans	-88.8	-28.1	-173.1	-68.3	-179.2	3.8	0	0	114.2	Y381 Y435 W437 V491 P492 A497 G498	Y381-Q495 HydrophobicContact CE1-CB 4.15Å; Y435-Q495 PolarHBondContact O-NE2 3.39Å; W437-Q495 VanDerWaalsContact N-OE1 3.12Å; W437-Q495 PolarHBondContact O-OE1 3.42Å; V491-Q495 HydrophobicContact CG1-CG 4.26Å; V491-Q495 WeakPolarHBondContact O-CB 3.06Å; V491-Q495 WeakPolarHBondContact O-CG 3.46Å; V491-Q495 PolarHBondContact O-N 3.46Å; P492-Q495 PolarHBondContact O-N 2.81Å; Q495-A497 PolarHBondContact O-N 3.06Å; Q495-G498 PolarHBondContact O-N 3.29Å
496	A	92.6	Very high	91.3	Very high	1 Å²	1	33 Å²	33	1%	0.008	18%	0.175	C	C	.	.	H	α-helix	trans	-58.3	-45.5	-173.7	0	0	0	0	0	114	I378 P492 G498 K499 M512	I378-A496 HydrophobicContact CB-CB 4.39Å; I378-A496 HydrophobicContact CD1-CB 4.4Å; I378-A496 HydrophobicContact CG2-CB 4.26Å; P492-A496 WeakPolarHBondContact O-CB 3.12Å; P492-A496 PolarHBondContact O-N 2.95Å; A496-G498 PolarHBondContact O-N 2.67Å; A496-K499 WeakPolarHBondContact O-CB 3.43Å; A496-K499 PolarHBondContact O-N 2.96Å; A496-M512 HydrophobicContact CB-CE 4.07Å; A496-M512 HydrophobicContact CB-CG 3.64Å; A496-M512 HydrophobicContact CB-SD 3.75Å
497	A	89.6	Confident	90.9	Very high	10 Å²	10	33.8 Å²	33.8	8%	0.083	18%	0.179	C	C	.	.	G	3₁₀ helix	trans	-64.7	-24.5	178.5	0	0	0	0	0	113	Q495 K499 R505	Q495-A497 PolarHBondContact O-N 3.06Å; A497-K499 PolarHBondContact O-N 3.11Å; A497-R505 WeakPolarHBondContact O-CG 3.47Å; A497-R505 PolarHBondContact O-NE 3.48Å
498	G	88.1	Confident	90.6	Very high	46 Å²	46	32 Å²	32	47%	0.474	17%	0.172	S	C	.	.	G	3₁₀ helix	trans	-74	-7.5	173.6	0	0	0	0	0	114.5	Q495 A496	Q495-G498 PolarHBondContact O-N 3.29Å; A496-G498 PolarHBondContact O-N 2.67Å
499	K	91	Very high	90.4	Very high	98 Å²	98	31.3 Å²	31.3	43%	0.426	17%	0.17	S	C	.	.	G	3₁₀ helix	trans	-98.7	-0.9	-180	-56.7	-64.7	174.4	172	0	113.8	V377 I378 Y381 A496 A497	V377-K499 HydrophobicContact CG1-CB 4.36Å; V377-K499 WeakPolarHBondContact CG1-O 3.38Å; I378-K499 HydrophobicContact CG2-CB 4.23Å; Y381-K499 HydrophobicContact CE2-CG 4.04Å; Y381-K499 VanDerWaalsContact OH-CE 3.28Å; Y381-K499 WeakPolarHBondContact OH-CE 3.47Å; A496-K499 WeakPolarHBondContact O-CB 3.43Å; A496-K499 PolarHBondContact O-N 2.96Å; A497-K499 PolarHBondContact O-N 3.11Å
500	V	90.3	Very high	90.2	Very high	9 Å²	9	31.3 Å²	31.3	6%	0.055	17%	0.17	C	C	.	.	S	Bend	trans	-122.7	156.2	-178.9	-58.5	0	0	0	0	112	V374 V377 I378 Q504 R505 A508	V374-V500 HydrophobicContact CG1-CG1 4.4Å; V377-V500 HydrophobicContact CG1-CG1 4.35Å; I378-V500 HydrophobicContact CG2-CG1 4.05Å; V500-Q504 HydrophobicContact CB-CB 4.18Å; V500-Q504 HydrophobicContact CG2-CB 4.21Å; V500-R505 HydrophobicContact CG2-CB 4.48Å; V500-R505 HydrophobicContact CG2-CG 3.84Å; V500-A508 HydrophobicContact CG1-CB 4.31Å; V500-A508 HydrophobicContact CG2-CB 3.72Å
501	P	87.3	Confident	89.9	Confident	72 Å²	72	31.7 Å²	31.7	47%	0.468	17%	0.173	S	C	.	.			trans	-55.8	151.2	173	-24.9	34.9	0	0	0	112.3	E503 Q504 R505	P501-E503 VanDerWaalsContact C-N 3.26Å; P501-E503 PolarHBondContact O-N 3.49Å; P501-E503 VanDerWaalsContact O-N 3.15Å; P501-Q504 PolarHBondContact O-N 2.67Å; P501-R505 PolarHBondContact O-N 3.11Å
502	P	84.5	Confident	89.8	Confident	62 Å²	62	31.5 Å²	31.5	40%	0.403	17%	0.172	S	C	.	.	G	3₁₀ helix	trans	-49.8	-42.4	-176.7	-29.2	36.3	0	0	0	114.5	A294 Q504 R505	A294-P502 HydrophobicContact CB-CB 4.27Å; P502-Q504 PolarHBondContact O-N 3.23Å; P502-R505 WeakPolarHBondContact O-CB 3.46Å; P502-R505 PolarHBondContact O-N 3.37Å
503	E	83.9	Confident	89.6	Confident	151 Å²	151	31.5 Å²	31.5	71%	0.706	17%	0.172	S	C	*	.	G	3₁₀ helix	trans	-60.3	-30.4	178.8	-63.9	164.9	-163.5	0	0	113.4	A294 P501	A294-E503 WeakPolarHBondContact O-CA 3.28Å; P501-E503 VanDerWaalsContact C-N 3.26Å; P501-E503 PolarHBondContact O-N 3.49Å; P501-E503 VanDerWaalsContact O-N 3.15Å
504	Q	87.3	Confident	89.4	Confident	34 Å²	34	32.7 Å²	32.7	16%	0.159	18%	0.179	C	C	.	.	G	3₁₀ helix	trans	-94.9	-2.9	-177.9	-62.8	-170.9	-21.5	0	0	113.2	H370 V374 V500 P501 P502 E506 L507 A508	H370-Q504 PolarHBondContact NE2-NE2 3.23Å; V374-Q504 HydrophobicContact CG2-CB 3.99Å; V374-Q504 HydrophobicContact CG2-CG 4.3Å; V500-Q504 HydrophobicContact CB-CB 4.18Å; V500-Q504 HydrophobicContact CG2-CB 4.21Å; P501-Q504 PolarHBondContact O-N 2.67Å; P502-Q504 PolarHBondContact O-N 3.23Å; Q504-E506 PolarHBondContact O-N 3.47Å; Q504-L507 WeakPolarHBondContact O-CB 3.25Å; Q504-L507 PolarHBondContact O-N 2.74Å; Q504-L507 VanDerWaalsContact O-N 3.11Å; Q504-A508 PolarHBondContact O-N 2.92Å
505	R	88.2	Confident	89.3	Confident	78 Å²	78	32.9 Å²	32.9	29%	0.294	18%	0.181	S	C	.	.	H	α-helix	trans	-65.2	-37.3	-175.2	-70.8	-175.2	-178.7	170.4	-0.1	113.8	G221 A497 V500 P501 P502 L507 A508 G509	G221-R505 WeakPolarHBondContact O-CB 3.5Å; G221-R505 VanDerWaalsContact O-CD 3.27Å; G221-R505 WeakPolarHBondContact O-CD 3.43Å; A497-R505 WeakPolarHBondContact O-CG 3.47Å; A497-R505 PolarHBondContact O-NE 3.48Å; V500-R505 HydrophobicContact CG2-CB 4.48Å; V500-R505 HydrophobicContact CG2-CG 3.84Å; P501-R505 PolarHBondContact O-N 3.11Å; P502-R505 WeakPolarHBondContact O-CB 3.46Å; P502-R505 PolarHBondContact O-N 3.37Å; R505-L507 VanDerWaalsContact C-N 3.27Å; R505-L507 PolarHBondContact O-N 3.18Å; R505-A508 PolarHBondContact O-N 3.32Å; R505-G509 PolarHBondContact O-N 2.98Å; R505-G509 VanDerWaalsContact O-N 3.11Å
506	E	88.3	Confident	89.2	Confident	39 Å²	39	33.2 Å²	33.2	18%	0.182	18%	0.182	C	C	.	.	H	α-helix	trans	-60	-43.4	173.2	-162	-161.8	142	0	0	110.2	R164 G218 M222 Q504 G509 N510	R164-E506 IonicContact CZ-OE1 3.66Å; R164-E506 IonicContact NH1-OE1 2.78Å; R164-E506 IonicContact NH2-OE1 2.82Å; R164-E506 PolarHBondContact NH2-OE1 3.28Å; G218-E506 VanDerWaalsContact CA-O 3.27Å; G218-E506 WeakPolarHBondContact CA-O 3.43Å; G218-E506 WeakPolarHBondContact O-CA 3.38Å; M222-E506 HydrophobicContact CG-CB 4.47Å; M222-E506 HydrophobicContact SD-CB 4.32Å; Q504-E506 PolarHBondContact O-N 3.47Å; E506-G509 PolarHBondContact O-N 2.98Å; E506-N510 PolarHBondContact O-N 2.9Å; E506-N510 PolarHBondContact O-ND2 2.94Å
507	L	87.3	Confident	89	Confident	15 Å²	15	33.8 Å²	33.8	8%	0.079	19%	0.185	C	C	.	.	H	α-helix	trans	-68.8	-38	-179	-166.1	58.2	0	0	0	112.4	H370 R371 V374 Q504 R505 N510 T511	H370-L507 WeakPolarHBondContact ND1-CD2 3.4Å; R371-L507 HydrophobicContact CG-CD1 3.78Å; R371-L507 HydrophobicContact CG-CD2 3.89Å; R371-L507 HydrophobicContact CG-CG 4.16Å; R371-L507 VanDerWaalsContact CZ-CD1 3.42Å; V374-L507 HydrophobicContact CG2-CD2 4.09Å; V374-L507 HydrophobicContact CG2-CG 4.47Å; Q504-L507 WeakPolarHBondContact O-CB 3.25Å; Q504-L507 PolarHBondContact O-N 2.74Å; Q504-L507 VanDerWaalsContact O-N 3.11Å; R505-L507 VanDerWaalsContact C-N 3.27Å; R505-L507 PolarHBondContact O-N 3.18Å; L507-N510 PolarHBondContact O-N 3.31Å; L507-T511 WeakPolarHBondContact O-CB 3.46Å; L507-T511 PolarHBondContact O-N 2.89Å; L507-T511 PolarHBondContact O-OG1 3.41Å
508	A	91.2	Very high	89	Confident	0 Å²	0	36.3 Å²	36.3	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-61.8	-46.5	175.3	0	0	0	0	0	112.1	V374 I378 V500 Q504 R505 T511 M512	V374-A508 HydrophobicContact CG1-CB 3.95Å; I378-A508 HydrophobicContact CD1-CB 4.14Å; V500-A508 HydrophobicContact CG1-CB 4.31Å; V500-A508 HydrophobicContact CG2-CB 3.72Å; Q504-A508 PolarHBondContact O-N 2.92Å; R505-A508 PolarHBondContact O-N 3.32Å; A508-T511 PolarHBondContact O-N 2.89Å; A508-M512 WeakPolarHBondContact O-CB 3.3Å; A508-M512 WeakPolarHBondContact O-CG 3.41Å; A508-M512 PolarHBondContact O-N 3.42Å
509	G	90.8	Very high	89.2	Confident	5 Å²	5	34.2 Å²	34.2	5%	0.052	18%	0.178	C	C	.	.	H	α-helix	trans	-63	-43.9	176.6	0	0	0	0	0	113.1	R505 E506 T511 M512 T513	R505-G509 PolarHBondContact O-N 2.98Å; R505-G509 VanDerWaalsContact O-N 3.11Å; E506-G509 PolarHBondContact O-N 2.98Å; G509-T511 PolarHBondContact O-N 3.31Å; G509-M512 PolarHBondContact O-N 3.44Å; G509-T513 PolarHBondContact O-N 2.89Å; G509-T513 VanDerWaalsContact O-N 3.13Å; G509-T513 PolarHBondContact O-OG1 3Å
510	N	88.8	Confident	89.1	Confident	0 Å²	0	31 Å²	31	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-58.8	-47.3	173	-73.1	-55.5	0	0	0	111.3	V156 S214 E506 L507 T513 V514	V156-N510 HydrophobicContact CG2-CB 4.34Å; S214-N510 PolarHBondContact O-OD1 3.38Å; E506-N510 PolarHBondContact O-N 2.9Å; E506-N510 PolarHBondContact O-ND2 2.94Å; L507-N510 PolarHBondContact O-N 3.31Å; N510-T513 WeakPolarHBondContact O-CB 3.3Å; N510-T513 PolarHBondContact O-N 3.46Å; N510-T513 VanDerWaalsContact O-N 3.1Å; N510-V514 PolarHBondContact O-N 3.06Å; N510-V514 VanDerWaalsContact O-N 3.14Å
511	T	89.5	Confident	88.9	Confident	9 Å²	9	34 Å²	34	6%	0.055	18%	0.179	C	C	.	.	H	α-helix	trans	-67.2	-36.8	-177.4	-57.8	0	0	0	0	112.5	S375 M382 L507 A508 G509 T513 V514 S515	S375-T511 WeakPolarHBondContact OG-CG2 3.39Å; M382-T511 HydrophobicContact CE-CG2 3.57Å; M382-T511 HydrophobicContact SD-CG2 3.78Å; L507-T511 WeakPolarHBondContact O-CB 3.46Å; L507-T511 PolarHBondContact O-N 2.89Å; L507-T511 PolarHBondContact O-OG1 3.41Å; A508-T511 PolarHBondContact O-N 2.89Å; G509-T511 PolarHBondContact O-N 3.31Å; T511-T513 VanDerWaalsContact C-N 3.29Å; T511-T513 PolarHBondContact O-N 3.33Å; T511-V514 WeakPolarHBondContact O-CB 3.41Å; T511-V514 PolarHBondContact O-N 3.48Å; T511-S515 PolarHBondContact O-N 3.22Å
512	M	92.3	Very high	89.1	Confident	1 Å²	1	33.8 Å²	33.8	1%	0.005	18%	0.177	C	C	.	.	H	α-helix	trans	-62.1	-37.1	170.4	-75.5	-65.2	-68.7	0	0	112	I378 M382 I385 P492 M493 A496 A508 G509 V514 S515 Y516	I378-M512 HydrophobicContact CD1-CG 3.92Å; I378-M512 HydrophobicContact CD1-SD 4.03Å; M382-M512 HydrophobicContact CB-SD 4.27Å; M382-M512 HydrophobicContact CG-SD 3.53Å; M382-M512 VanDerWaalsContact CG-SD 3.53Å; I385-M512 HydrophobicContact CB-CE 4.39Å; I385-M512 HydrophobicContact CG2-CE 3.79Å; P492-M512 HydrophobicContact CB-CE 3.9Å; M493-M512 HydrophobicContact CE-CB 3.92Å; M493-M512 HydrophobicContact SD-CB 3.49Å; M493-M512 WeakPolarHBondContact SD-CB 3.37Å; M493-M512 HydrophobicContact SD-CG 4.32Å; A496-M512 HydrophobicContact CB-CE 4.07Å; A496-M512 HydrophobicContact CB-CG 3.64Å; A496-M512 HydrophobicContact CB-SD 3.75Å; A508-M512 WeakPolarHBondContact O-CB 3.3Å; A508-M512 WeakPolarHBondContact O-CG 3.41Å; A508-M512 PolarHBondContact O-N 3.42Å; G509-M512 PolarHBondContact O-N 3.44Å; M512-V514 VanDerWaalsContact C-N 3.35Å; M512-S515 PolarHBondContact O-N 2.87Å; M512-Y516 WeakPolarHBondContact O-CB 3.43Å; M512-Y516 PolarHBondContact O-N 3.12Å
513	T	90.3	Very high	89.3	Confident	0 Å²	0	30.8 Å²	30.8	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-65.9	-37.3	175.9	-44.4	0	0	0	0	111.9	S214 Y217 G509 N510 T511 S515 Y516 M517	S214-T513 WeakPolarHBondContact OG-CB 3.31Å; Y217-T513 VanDerWaalsContact CB-OG1 3.32Å; Y217-T513 WeakPolarHBondContact CB-OG1 3.41Å; Y217-T513 HydrophobicContact CD2-CG2 4.36Å; G509-T513 PolarHBondContact O-N 2.89Å; G509-T513 VanDerWaalsContact O-N 3.13Å; G509-T513 PolarHBondContact O-OG1 3Å; N510-T513 WeakPolarHBondContact O-CB 3.3Å; N510-T513 PolarHBondContact O-N 3.46Å; N510-T513 VanDerWaalsContact O-N 3.1Å; T511-T513 VanDerWaalsContact C-N 3.29Å; T511-T513 PolarHBondContact O-N 3.33Å; T513-S515 VanDerWaalsContact C-N 3.33Å; T513-S515 PolarHBondContact O-N 3.15Å; T513-Y516 HydrophobicContact CG2-CD1 4.36Å; T513-Y516 PolarHBondContact O-N 2.96Å; T513-M517 HydrophobicContact CG2-CG 4.38Å; T513-M517 WeakPolarHBondContact O-CB 3.48Å; T513-M517 WeakPolarHBondContact O-CG 3.48Å; T513-M517 PolarHBondContact O-N 3.16Å
514	V	89.1	Confident	89.4	Confident	32 Å²	32	24.8 Å²	24.8	19%	0.194	13%	0.132	C	C	.	.	H	α-helix	trans	-57.3	-49.1	172.6	178.8	0	0	0	0	109.9	V149 N510 T511 M512 Y516 M517 T518	V149-V514 HydrophobicContact CG1-CB 4.07Å; V149-V514 HydrophobicContact CG1-CG1 3.81Å; V149-V514 HydrophobicContact CG1-CG2 3.95Å; N510-V514 PolarHBondContact O-N 3.06Å; N510-V514 VanDerWaalsContact O-N 3.14Å; T511-V514 WeakPolarHBondContact O-CB 3.41Å; T511-V514 PolarHBondContact O-N 3.48Å; M512-V514 VanDerWaalsContact C-N 3.35Å; V514-Y516 PolarHBondContact O-N 2.74Å; V514-M517 PolarHBondContact O-N 3.15Å; V514-T518 PolarHBondContact O-N 2.91Å; V514-T518 PolarHBondContact O-OG1 3.06Å
515	S	92	Very high	89.3	Confident	16 Å²	16	26 Å²	26	11%	0.112	14%	0.144	C	C	.	.	H	α-helix	trans	-64	-41.5	-179.6	-150.9	0	0	0	0	113	M382 A386 T511 M512 T513 T518 G519	M382-S515 VanDerWaalsContact C-OG 3.25Å; M382-S515 WeakPolarHBondContact CB-OG 3.49Å; M382-S515 PolarHBondContact O-OG 2.97Å; A386-S515 WeakPolarHBondContact CB-O 3.33Å; T511-S515 PolarHBondContact O-N 3.22Å; M512-S515 PolarHBondContact O-N 2.87Å; T513-S515 VanDerWaalsContact C-N 3.33Å; T513-S515 PolarHBondContact O-N 3.15Å; S515-T518 PolarHBondContact O-N 3.39Å; S515-G519 PolarHBondContact O-N 3.15Å
516	Y	91.4	Very high	89.2	Confident	19 Å²	19	25.4 Å²	25.4	8%	0.075	15%	0.149	C	C	.	.	H	α-helix	trans	-56	-52.4	172.8	165.8	-131.9	0	0	0	111.8	I385 Y389 M512 T513 V514 T518 G519 L520	I385-Y516 HydrophobicContact CD1-CD2 4.45Å; I385-Y516 HydrophobicContact CD1-CG 4.43Å; I385-Y516 HydrophobicContact CG1-CD2 4.42Å; Y389-Y516 HydrophobicContact CD1-CD2 4.31Å; Y389-Y516 AromaticContact CD1-CE2 3.68Å; Y389-Y516 HydrophobicContact CD1-CE2 3.68Å; Y389-Y516 AromaticContact CD2-CD2 3.4Å; Y389-Y516 HydrophobicContact CD2-CD2 3.4Å; Y389-Y516 VanDerWaalsContact CD2-CD2 3.4Å; Y389-Y516 AromaticContact CD2-CE2 3.57Å; Y389-Y516 HydrophobicContact CD2-CE2 3.57Å; Y389-Y516 HydrophobicContact CE1-CD2 4.45Å; Y389-Y516 AromaticContact CE1-CE2 3.62Å; Y389-Y516 HydrophobicContact CE1-CE2 3.62Å; Y389-Y516 AromaticContact CE2-CD2 3.57Å; Y389-Y516 HydrophobicContact CE2-CD2 3.57Å; Y389-Y516 AromaticContact CE2-CE2 3.49Å; Y389-Y516 HydrophobicContact CE2-CE2 3.49Å; Y389-Y516 VanDerWaalsContact CE2-CE2 3.49Å; Y389-Y516 AromaticContact CG-CD2 3.78Å; Y389-Y516 HydrophobicContact CG-CD2 3.78Å; Y389-Y516 AromaticContact CG-CE2 3.64Å; Y389-Y516 HydrophobicContact CG-CE2 3.64Å; Y389-Y516 AromaticContact CZ-CE2 3.51Å; M512-Y516 WeakPolarHBondContact O-CB 3.43Å; M512-Y516 PolarHBondContact O-N 3.12Å; T513-Y516 HydrophobicContact CG2-CD1 4.36Å; T513-Y516 PolarHBondContact O-N 2.96Å; V514-Y516 PolarHBondContact O-N 2.74Å; Y516-T518 PolarHBondContact O-N 2.99Å; Y516-G519 WeakPolarHBondContact O-CA 3.42Å; Y516-G519 PolarHBondContact O-N 3.23Å; Y516-G519 VanDerWaalsContact O-N 3.09Å; Y516-L520 HydrophobicContact CD2-CD1 4.24Å; Y516-L520 HydrophobicContact CD2-CG 4.2Å; Y516-L520 HydrophobicContact CE1-CD1 4.15Å; Y516-L520 HydrophobicContact CE2-CD1 3.69Å; Y516-L520 HydrophobicContact CE2-CD2 3.92Å; Y516-L520 HydrophobicContact CE2-CG 3.84Å; Y516-L520 PolarHBondContact O-N 3.08Å
517	M	88.4	Confident	89	Confident	14 Å²	14	24.8 Å²	24.8	7%	0.069	15%	0.15	C	C	.	.	H	α-helix	trans	-65.5	-36.1	179.7	-71.6	-73.6	-177.1	0	0	112.9	V149 T513 V514 G519 L520 M521	V149-M517 HydrophobicContact CG2-CB 3.61Å; V149-M517 HydrophobicContact CG2-CG 3.64Å; T513-M517 HydrophobicContact CG2-CG 4.38Å; T513-M517 WeakPolarHBondContact O-CB 3.48Å; T513-M517 WeakPolarHBondContact O-CG 3.48Å; T513-M517 PolarHBondContact O-N 3.16Å; V514-M517 PolarHBondContact O-N 3.15Å; M517-G519 VanDerWaalsContact C-N 3.33Å; M517-L520 PolarHBondContact O-N 3.43Å; M517-L520 HydrophobicContact SD-CD1 3.84Å; M517-M521 PolarHBondContact O-N 2.87Å
518	T	89	Confident	88.6	Confident	62 Å²	62	30.2 Å²	30.2	38%	0.38	17%	0.171	S	C	.	.	H	α-helix	trans	-62.3	-40.7	170.6	-59.7	0	0	0	0	111.4	V514 S515 Y516 M521 V522	V514-T518 PolarHBondContact O-N 2.91Å; V514-T518 PolarHBondContact O-OG1 3.06Å; S515-T518 PolarHBondContact O-N 3.39Å; Y516-T518 PolarHBondContact O-N 2.99Å; T518-M521 PolarHBondContact O-N 2.95Å; T518-V522 HydrophobicContact CG2-CG2 4.37Å; T518-V522 WeakPolarHBondContact O-CG2 3.47Å; T518-V522 PolarHBondContact O-N 2.87Å
519	G	92.2	Very high	88.1	Confident	2 Å²	2	31.9 Å²	31.9	2%	0.021	19%	0.185	C	C	.	.	H	α-helix	trans	-57.7	-50.2	172.6	0	0	0	0	0	112.7	A386 S390 S515 Y516 M517 M521 V522 G523	A386-G519 VanDerWaalsContact O-CA 3.23Å; A386-G519 WeakPolarHBondContact O-CA 3.36Å; S390-G519 WeakPolarHBondContact CA-O 3.1Å; S390-G519 WeakPolarHBondContact CB-O 3.32Å; S390-G519 PolarHBondContact N-O 3.05Å; S515-G519 PolarHBondContact O-N 3.15Å; Y516-G519 WeakPolarHBondContact O-CA 3.42Å; Y516-G519 PolarHBondContact O-N 3.23Å; Y516-G519 VanDerWaalsContact O-N 3.09Å; M517-G519 VanDerWaalsContact C-N 3.33Å; G519-M521 VanDerWaalsContact C-N 3.34Å; G519-M521 PolarHBondContact O-N 2.88Å; G519-V522 PolarHBondContact O-N 2.97Å; G519-G523 PolarHBondContact O-N 3.11Å
520	L	89.1	Confident	87.4	Confident	32 Å²	32	35.5 Å²	35.5	17%	0.168	21%	0.206	C	C	.	.	H	α-helix	trans	-56.9	-45.2	176.6	-63.7	174.4	0	0	0	112	Y389 L393 Y516 M517 S524	Y389-L520 HydrophobicContact CD1-CD2 3.76Å; Y389-L520 HydrophobicContact CG-CD2 4.11Å; L393-L520 HydrophobicContact CD1-CB 3.84Å; L393-L520 HydrophobicContact CD1-CD2 3.5Å; L393-L520 VanDerWaalsContact CD1-CD2 3.5Å; L393-L520 HydrophobicContact CD1-CG 4.25Å; L393-L520 HydrophobicContact CG-CD2 3.77Å; Y516-L520 HydrophobicContact CD2-CD1 4.24Å; Y516-L520 HydrophobicContact CD2-CG 4.2Å; Y516-L520 HydrophobicContact CE1-CD1 4.15Å; Y516-L520 HydrophobicContact CE2-CD1 3.69Å; Y516-L520 HydrophobicContact CE2-CD2 3.92Å; Y516-L520 HydrophobicContact CE2-CG 3.84Å; Y516-L520 PolarHBondContact O-N 3.08Å; M517-L520 PolarHBondContact O-N 3.43Å; M517-L520 HydrophobicContact SD-CD1 3.84Å; L520-S524 WeakPolarHBondContact O-CB 3.09Å; L520-S524 PolarHBondContact O-N 3.25Å; L520-S524 PolarHBondContact O-OG 2.96Å
521	M	86.9	Confident	86.5	Confident	71 Å²	71	41.6 Å²	41.6	35%	0.35	23%	0.23	S	C	.	.	H	α-helix	trans	-59.7	-50.9	175.9	166.8	-168.7	-179.9	0	0	112.4	L146 M517 T518 G519 G523 S524 S525	L146-M521 HydrophobicContact CD1-CB 3.97Å; L146-M521 HydrophobicContact CD1-CE 4.17Å; L146-M521 HydrophobicContact CD1-CG 3.61Å; L146-M521 HydrophobicContact CD1-SD 3.51Å; L146-M521 VanDerWaalsContact CD1-SD 3.51Å; L146-M521 HydrophobicContact CD2-CB 3.81Å; L146-M521 HydrophobicContact CD2-CG 4Å; L146-M521 HydrophobicContact CD2-SD 3.37Å; L146-M521 WeakPolarHBondContact CD2-SD 3.17Å; L146-M521 HydrophobicContact CG-CB 4.29Å; L146-M521 HydrophobicContact CG-CG 4.36Å; L146-M521 HydrophobicContact CG-SD 4.06Å; M517-M521 PolarHBondContact O-N 2.87Å; T518-M521 PolarHBondContact O-N 2.95Å; G519-M521 VanDerWaalsContact C-N 3.34Å; G519-M521 PolarHBondContact O-N 2.88Å; M521-G523 VanDerWaalsContact C-N 3.34Å; M521-G523 PolarHBondContact O-N 3.38Å; M521-S524 PolarHBondContact O-N 2.7Å; M521-S525 WeakPolarHBondContact O-CB 3.23Å; M521-S525 PolarHBondContact O-N 3Å; M521-S525 PolarHBondContact O-OG 3.45Å
522	V	90.1	Very high	85.5	Confident	67 Å²	67	43.7 Å²	43.7	41%	0.406	25%	0.245	S	C	.	.	H	α-helix	trans	-62.8	-44.2	-176.2	174.7	0	0	0	0	109.9	S390 T518 G519 S525 V526	S390-V522 WeakPolarHBondContact OG-CG1 3.39Å; T518-V522 HydrophobicContact CG2-CG2 4.37Å; T518-V522 WeakPolarHBondContact O-CG2 3.47Å; T518-V522 PolarHBondContact O-N 2.87Å; G519-V522 PolarHBondContact O-N 2.97Å; V522-S525 PolarHBondContact O-N 3.09Å; V522-V526 HydrophobicContact CG1-CG2 4.48Å; V522-V526 VanDerWaalsContact O-CG2 3.3Å; V522-V526 WeakPolarHBondContact O-CG2 3.21Å; V522-V526 PolarHBondContact O-N 3.24Å
523	G	90	Very high	84.1	Confident	0 Å²	0	52 Å²	52	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-58.2	-50.2	174.4	0	0	0	0	0	113	S390 G519 M521 S525 V526 A527	S390-G523 WeakPolarHBondContact O-CA 3.47Å; S390-G523 PolarHBondContact OG-N 3.41Å; G519-G523 PolarHBondContact O-N 3.11Å; M521-G523 VanDerWaalsContact C-N 3.34Å; M521-G523 PolarHBondContact O-N 3.38Å; G523-S525 VanDerWaalsContact C-N 3.32Å; G523-S525 PolarHBondContact O-N 3.18Å; G523-V526 PolarHBondContact O-N 2.88Å; G523-A527 PolarHBondContact O-N 2.87Å
524	S	85	Confident	82.6	Confident	25 Å²	25	54.8 Å²	54.8	18%	0.175	30%	0.299	C	S	.	.	H	α-helix	trans	-61.6	-38.9	178.8	-54	0	0	0	0	112.7	L393 L520 M521 Y528	L393-S524 WeakPolarHBondContact CD1-OG 3.49Å; L520-S524 WeakPolarHBondContact O-CB 3.09Å; L520-S524 PolarHBondContact O-N 3.25Å; L520-S524 PolarHBondContact O-OG 2.96Å; M521-S524 PolarHBondContact O-N 2.7Å; S524-Y528 WeakPolarHBondContact O-CB 3.3Å; S524-Y528 PolarHBondContact O-N 3.25Å
525	S	84.4	Confident	80.5	Confident	58 Å²	58	58.5 Å²	58.5	41%	0.406	32%	0.324	S	S	.	.	H	α-helix	trans	-68.3	-40.4	179	-55.8	0	0	0	0	111.6	M521 V522 G523 A529	M521-S525 WeakPolarHBondContact O-CB 3.23Å; M521-S525 PolarHBondContact O-N 3Å; M521-S525 PolarHBondContact O-OG 3.45Å; V522-S525 PolarHBondContact O-N 3.09Å; G523-S525 VanDerWaalsContact C-N 3.32Å; G523-S525 PolarHBondContact O-N 3.18Å; S525-A529 WeakPolarHBondContact O-CB 3.37Å; S525-A529 PolarHBondContact O-N 2.71Å
526	V	87.7	Confident	78.3	Confident	66 Å²	66	62.5 Å²	62.5	40%	0.4	35%	0.347	S	S	.	.	H	α-helix	trans	-67	-46.2	175.1	174	0	0	0	0	110.4	V522 G523 Y528 A529 T530	V522-V526 HydrophobicContact CG1-CG2 4.48Å; V522-V526 VanDerWaalsContact O-CG2 3.3Å; V522-V526 WeakPolarHBondContact O-CG2 3.21Å; V522-V526 PolarHBondContact O-N 3.24Å; G523-V526 PolarHBondContact O-N 2.88Å; V526-Y528 VanDerWaalsContact C-N 3.33Å; V526-Y528 PolarHBondContact O-N 3.07Å; V526-A529 PolarHBondContact O-N 2.9Å; V526-T530 WeakPolarHBondContact O-CB 3.33Å; V526-T530 PolarHBondContact O-N 2.65Å; V526-T530 PolarHBondContact O-OG1 3.37Å
527	A	84.1	Confident	75.7	Confident	26 Å²	26	63 Å²	63	22%	0.215	36%	0.355	C	S	.	.	H	α-helix	trans	-55.9	-46.8	175.2	0	0	0	0	0	112	G523 T530 Y531	G523-A527 PolarHBondContact O-N 2.87Å; A527-T530 PolarHBondContact O-N 3.04Å; A527-Y531 WeakPolarHBondContact O-CB 3.21Å; A527-Y531 PolarHBondContact O-N 3.01Å
528	Y	78.8	Confident	72.8	Confident	129 Å²	129	66.3 Å²	66.3	51%	0.506	39%	0.385	S	S	.	.	H	α-helix	trans	-63.6	-41.9	177.6	178.9	-100.6	0	0	0	112.9	F135 S524 V526 Y531 S532	F135-Y528 AromaticContact CE2-CD2 3.92Å; F135-Y528 HydrophobicContact CE2-CD2 3.92Å; F135-Y528 AromaticContact CE2-CE2 3.96Å; F135-Y528 HydrophobicContact CE2-CE2 3.96Å; F135-Y528 AromaticContact CZ-CD2 3.85Å; F135-Y528 HydrophobicContact CZ-CD2 3.85Å; F135-Y528 AromaticContact CZ-CE2 3.49Å; F135-Y528 HydrophobicContact CZ-CE2 3.49Å; F135-Y528 VanDerWaalsContact CZ-CE2 3.49Å; S524-Y528 WeakPolarHBondContact O-CB 3.3Å; S524-Y528 PolarHBondContact O-N 3.25Å; V526-Y528 VanDerWaalsContact C-N 3.33Å; V526-Y528 PolarHBondContact O-N 3.07Å; Y528-Y531 PolarHBondContact O-N 2.92Å; Y528-S532 WeakPolarHBondContact O-CB 3.49Å; Y528-S532 PolarHBondContact O-N 2.98Å; Y528-S532 PolarHBondContact O-OG 3.38Å
529	A	81.3	Confident	70.1	Confident	36 Å²	36	66.7 Å²	66.7	30%	0.298	40%	0.401	S	S	.	.	H	α-helix	trans	-62.3	-48.8	175.6	0	0	0	0	0	111	S525 V526 Y531 S532 F533	S525-A529 WeakPolarHBondContact O-CB 3.37Å; S525-A529 PolarHBondContact O-N 2.71Å; V526-A529 PolarHBondContact O-N 2.9Å; A529-Y531 VanDerWaalsContact C-N 3.34Å; A529-Y531 PolarHBondContact O-N 2.64Å; A529-S532 WeakPolarHBondContact O-CB 3.37Å; A529-S532 PolarHBondContact O-N 2.82Å; A529-S532 VanDerWaalsContact O-N 3.13Å; A529-F533 HydrophobicContact CB-CE2 4.29Å; A529-F533 WeakPolarHBondContact O-CD2 3.36Å; A529-F533 PolarHBondContact O-N 2.79Å
530	T	75.4	Confident	67.3	Low	81 Å²	81	70.6 Å²	70.6	50%	0.497	43%	0.433	S	S	.	.	H	α-helix	trans	-58.7	-43.6	177.5	-58.2	0	0	0	0	111.9	V526 A527 F533 T534	V526-T530 WeakPolarHBondContact O-CB 3.33Å; V526-T530 PolarHBondContact O-N 2.65Å; V526-T530 PolarHBondContact O-OG1 3.37Å; A527-T530 PolarHBondContact O-N 3.04Å; T530-F533 PolarHBondContact O-N 2.93Å; T530-T534 PolarHBondContact O-N 3.43Å; T530-T534 PolarHBondContact O-OG1 2.77Å
531	Y	69.1	Low	64.6	Low	127 Å²	127	79 Å²	79	50%	0.498	46%	0.463	S	S	.	.	H	α-helix	trans	-62.2	-43.2	174.9	-169.3	-91.6	0	0	0	111.8	A527 Y528 A529 F533 T534	A527-Y531 WeakPolarHBondContact O-CB 3.21Å; A527-Y531 PolarHBondContact O-N 3.01Å; Y528-Y531 PolarHBondContact O-N 2.92Å; A529-Y531 VanDerWaalsContact C-N 3.34Å; A529-Y531 PolarHBondContact O-N 2.64Å; Y531-F533 VanDerWaalsContact C-N 3.31Å; Y531-F533 PolarHBondContact O-N 2.88Å; Y531-T534 WeakPolarHBondContact O-CB 3.32Å; Y531-T534 PolarHBondContact O-N 2.96Å; Y531-T534 VanDerWaalsContact O-N 3.12Å
532	S	68.5	Low	61.9	Low	54 Å²	54	82.3 Å²	82.3	38%	0.378	48%	0.481	S	S	.	.	H	α-helix	trans	-64.5	-31.1	178.7	-59	0	0	0	0	113.7	Y528 A529	Y528-S532 WeakPolarHBondContact O-CB 3.49Å; Y528-S532 PolarHBondContact O-N 2.98Å; Y528-S532 PolarHBondContact O-OG 3.38Å; A529-S532 WeakPolarHBondContact O-CB 3.37Å; A529-S532 PolarHBondContact O-N 2.82Å; A529-S532 VanDerWaalsContact O-N 3.13Å
533	F	64.2	Low	59.1	Low	175 Å²	175	84.7 Å²	84.7	77%	0.768	50%	0.498	S	S	*	.	H	α-helix	trans	-84.1	-7.7	175.2	-68.3	-59.4	0	0	0	113.9	A529 T530 Y531	A529-F533 HydrophobicContact CB-CE2 4.29Å; A529-F533 WeakPolarHBondContact O-CD2 3.36Å; A529-F533 PolarHBondContact O-N 2.79Å; T530-F533 PolarHBondContact O-N 2.93Å; Y531-F533 VanDerWaalsContact C-N 3.31Å; Y531-F533 PolarHBondContact O-N 2.88Å
534	T	57.5	Low	56.4	Low	59 Å²	59	89.2 Å²	89.2	36%	0.362	53%	0.525	S	S	.	.	S	Bend	trans	-80.9	124.7	178.8	-54.4	0	0	0	0	109.5	T530 Y531 T536 A537	T530-T534 PolarHBondContact O-N 3.43Å; T530-T534 PolarHBondContact O-OG1 2.77Å; Y531-T534 WeakPolarHBondContact O-CB 3.32Å; Y531-T534 PolarHBondContact O-N 2.96Å; Y531-T534 VanDerWaalsContact O-N 3.12Å; T534-T536 WeakPolarHBondContact CG2-OG1 3.43Å; T534-T536 PolarHBondContact O-N 2.78Å; T534-A537 PolarHBondContact O-N 2.86Å
535	P	45.5	Very low	54	Low	110 Å²	110	96.9 Å²	96.9	71%	0.714	56%	0.558	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64.7	-10.7	-168.8	22	-33	0	0	0	115.4	A537 A538	P535-A537 VanDerWaalsContact C-N 3.25Å; P535-A537 PolarHBondContact O-N 2.78Å; P535-A538 PolarHBondContact O-N 2.99Å
536	T	46.2	Very low	51.2	Low	100 Å²	100	98.4 Å²	98.4	61%	0.613	57%	0.574	S	S	*	*	H	α-helix	trans	-59.7	-32.7	168.4	41.4	0	0	0	0	112.8	T534 A538 G539	T534-T536 WeakPolarHBondContact CG2-OG1 3.43Å; T534-T536 PolarHBondContact O-N 2.78Å; T536-A538 VanDerWaalsContact C-N 3.32Å; T536-A538 PolarHBondContact O-N 2.92Å; T536-G539 PolarHBondContact O-N 3.37Å
537	A	35.7	Very low	48.4	Very low	29 Å²	29	100.8 Å²	100.8	24%	0.24	59%	0.591	C	S	.	*	H	α-helix	trans	-70.1	-27.4	178	0	0	0	0	0	113.2	T534 P535	T534-A537 PolarHBondContact O-N 2.86Å; P535-A537 VanDerWaalsContact C-N 3.25Å; P535-A537 PolarHBondContact O-N 2.78Å
538	A	28.7	Very low	45.8	Very low	84 Å²	84	110.1 Å²	110.1	69%	0.694	63%	0.627	S	S	*	*	H	α-helix	trans	-74.6	-28.4	177.4	0	0	0	0	0	112.7	P535 T536	P535-A538 PolarHBondContact O-N 2.99Å; T536-A538 VanDerWaalsContact C-N 3.32Å; T536-A538 PolarHBondContact O-N 2.92Å
539	G	32	Very low	43.3	Very low	69 Å²	69	111 Å²	111	71%	0.711	64%	0.641	S	S	*	*	H	α-helix	trans	-78.3	-14.9	176.5	0	0	0	0	0	114.8	T536	T536-G539 PolarHBondContact O-N 3.37Å
540	A	33.5	Very low	40.9	Very low	84 Å²	84	113.2 Å²	113.2	69%	0.694	66%	0.659	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.1	-1.9	-176.1	0	0	0	0	0	114.4
541	R	32.8	Very low	38.7	Very low	210 Å²	210	116.4 Å²	116.4	79%	0.792	68%	0.678	S	S	*	*	S	Bend	trans	-116.3	83.8	-179.1	-69.5	-173.4	177.3	-179.4	0.9	111.9
542	L	28.6	Very low	36.7	Very low	139 Å²	139	113.1 Å²	113.1	73%	0.728	68%	0.683	S	S	*	*			trans	73.4	151.1	164.6	-70.3	164.1	0	0	0	115.6	T544	L542-T544 HydrophobicContact CD2-CG2 3.83Å
543	P	31.7	Very low	34.9	Very low	117 Å²	117	125.8 Å²	125.8	76%	0.76	73%	0.725	S	S	*	*			cis	-105.8	137.3	33.2	38.1	-31.5	0	0	0	115.4
544	T	34.5	Very low	33.4	Very low	95 Å²	95	123.3 Å²	123.3	58%	0.583	72%	0.723	S	S	*	*				40.9	114.6	86.4	37	0	0	0	0	116.8	L542	L542-T544 HydrophobicContact CD2-CG2 3.83Å
545	H	33.4	Very low	32.2	Very low	187 Å²	187	126.7 Å²	126.7	87%	0.866	74%	0.742	S	S	*	*			trans	56.2	103.6	159.2	-69.5	-81.1	0	0	0	119.2
546	A	26.4	Very low	31.4	Very low	90 Å²	90	127.6 Å²	127.6	74%	0.744	74%	0.743	S	S	*	*			trans	-128.8	131.9	137	0	0	0	0	0	108.1
547	P	28.8	Very low	30.6	Very low	116 Å²	116	129.2 Å²	129.2	75%	0.753	75%	0.751	S	S	*	*			trans	-74.8	134.3	179.5	30.3	-33.1	0	0	0	110.6	N549	P547-N549 VanDerWaalsContact C-N 3.32Å; P547-N549 PolarHBondContact O-N 3.43Å
548	F	28.3	Very low	30.2	Very low	221 Å²	221	135.5 Å²	135.5	97%	0.969	78%	0.783	S	S	*	*			trans	-72	89.6	168.3	-118.6	-86.3	0	0	0	109
549	N	27.7	Very low	30.3	Very low	149 Å²	149	138.9 Å²	138.9	80%	0.797	79%	0.789	S	S	*	*			trans	-80.2	150.3	164.7	-114.1	-4.4	0	0	0	109.7	P547	P547-N549 VanDerWaalsContact C-N 3.32Å; P547-N549 PolarHBondContact O-N 3.43Å
550	A	30.2	Very low	30.2	Very low	81 Å²	81	143.9 Å²	143.9	67%	0.669	79%	0.794	S	S	*	*			trans	-79.4	177.6	-165.6	0	0	0	0	0	115.4
551	T	28.6	Very low	30	Very low	148 Å²	148	148.5 Å²	148.5	91%	0.908	80%	0.802	S	S	*	*			trans	76.5	141	172.4	75.7	0	0	0	0	115.4
552	G	27.3	Very low	29.7	Very low	59 Å²	59	143.4 Å²	143.4	61%	0.608	80%	0.803	S	S	*	*			cis	176.8	170.2	-5.1	0	0	0	0	0	111.5
553	Y	31.2	Very low	29.8	Very low	319 Å²	319	143.8 Å²	143.8	100%	1.251	81%	0.81	S	S	*	*			trans	79	0	-172.1	-58.4	-77.2	0	0	0	116.2

Retrieved 553 of 553 residues in 110.1 ms (Link to these results)

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