A0A087YC97_POEFO Loading...

WD repeat-containing protein 48

AlphaFold DB , UniProt , Accession A0A087YC97, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 682 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M32.2Very low32.4Very low250 Ų250154.1 Ų154.1100%1.23287%0.868SS**  092.20-71.6-174.1-163.400107.9
2A28.2Very low34.7Very low96 Ų96160.8 Ų160.879%0.79387%0.87SS**  trans-105.6116.5177.900000107.6H4A2-H4 PolarHBondContact O-N 3.47Å
3T27.2Very low38.2Very low137 Ų137159.5 Ų159.584%0.8484%0.844SS**  trans-69.9108.6178.531.60000109.5H5T3-H5 PolarHBondContact O-N 3.48Å
4H29.8Very low42Very low189 Ų189155.9 Ų155.988%0.87582%0.818SS**  trans-62.5105164.7-85.5-78.8000109.1A2 R6A2-H4 PolarHBondContact O-N 3.47Å; H4-R6 VanDerWaalsContact C-N 3.35Å; H4-R6 PolarHBondContact O-N 2.91Å
5H29.3Very low45.6Very low182 Ų182147.3 Ų147.384%0.84378%0.775SS**  trans-6698.1160.7-99.9-48.3000108.4T3 Q7T3-H5 PolarHBondContact O-N 3.48Å; H5-Q7 VanDerWaalsContact C-N 3.34Å; H5-Q7 PolarHBondContact O-N 3.02Å
6R31.8Very low48.9Very low235 Ų235141 Ų14189%0.88774%0.74SS**  trans-56.5101.8154.9-91.8-178.9172.4175.7-2.3107H4 N8H4-R6 VanDerWaalsContact C-N 3.35Å; H4-R6 PolarHBondContact O-N 2.91Å; R6-N8 PolarHBondContact O-N 3.08Å
7Q32.7Very low51.8Low175 Ų175132.8 Ų132.882%0.81870%0.697SS**  trans-61.2126.3161.7-79.9-178.3-7.100107.7H5 A9H5-Q7 VanDerWaalsContact C-N 3.34Å; H5-Q7 PolarHBondContact O-N 3.02Å; Q7-A9 PolarHBondContact O-N 3.37Å
8N29Very low54.4Low154 Ų154126.3 Ų126.382%0.82466%0.664SS**  trans-46.1119.9175.5-82-28.8000111.3R6 A10R6-N8 PolarHBondContact O-N 3.08Å; N8-A10 PolarHBondContact O-N 2.99Å
9A36.2Very low56.7Low113 Ų113119.7 Ų119.793%0.93463%0.629SS**  trans-75.349.3171.200000111.7Q7Q7-A9 PolarHBondContact O-N 3.37Å
10A35.1Very low58.8Low91 Ų91114.4 Ų114.475%0.75260%0.602SS**  trans-111.9102.8174.600000108.5N8N8-A10 PolarHBondContact O-N 2.99Å
11G45Very low60.7Low73 Ų73109.2 Ų109.275%0.75358%0.575SS**  trans11512.9161.400000119R13G11-R13 PolarHBondContact O-N 3.22Å
12R60.4Low63.9Low235 Ų23598.5 Ų98.589%0.88752%0.521SS*.PPolyproline II helixtrans-68.8123.2168.2-76.7-171.7-178.3-179.50.6109.3
13R79.9Confident67.2Low143 Ų14399.1 Ų99.154%0.5451%0.511SS..PPolyproline II helixtrans-62.3147.1175.2-67.7174.1177-159.55.2109.1G11 E524 A525G11-R13 PolarHBondContact O-N 3.22Å; R13-E524 HydrophobicContact CB-CB 4.01Å; R13-E524 HydrophobicContact CB-CG 4.3Å; R13-A525 WeakPolarHBondContact CD-O 3.32Å
14K91.3Very high70.6Confident109 Ų10997.3 Ų97.347%0.47449%0.493SS..PPolyproline II helixtrans-59.8138.1176.8-66.8-170.6171.9-138.90110.1E439 A525K14-E439 IonicContact NZ-OE2 3.14Å; K14-E439 PolarHBondContact NZ-OE2 3.41Å; K14-A525 PolarHBondContact O-N 3.05Å
15V96.3Very high73.8Confident28 Ų2892.4 Ų92.417%0.1748%0.476CS..EExtended strand (participates in β ladder)trans-92.6128.2177.1-1790000108.9F522 G523 L530 P552 W554V15-F522 HydrophobicContact CG1-CB 4.39Å; V15-G523 CarbonylContact C-O 3.58Å; V15-G523 WeakPolarHBondContact CA-O 3.42Å; V15-L530 HydrophobicContact CG1-CD1 4.07Å; V15-L530 HydrophobicContact CG2-CD1 3.75Å; V15-P552 HydrophobicContact CB-CB 4.07Å; V15-P552 HydrophobicContact CB-CG 4.07Å; V15-P552 HydrophobicContact CG1-CB 4.5Å; V15-P552 HydrophobicContact CG1-CG 4.08Å; V15-W554 PolarHBondContact O-NE1 2.98Å
16Q97.8Very high77.1Confident46 Ų4684.3 Ų84.322%0.21544%0.438CS..EExtended strand (participates in β ladder)trans-104.9151177.2-60.8-179.9-47.400109.7T436 L437 D438 G523 A525Q16-T436 HydrophobicContact CB-CG2 3.93Å; Q16-T436 HydrophobicContact CG-CG2 4.4Å; Q16-L437 WeakPolarHBondContact CA-O 3.33Å; Q16-D438 WeakPolarHBondContact CG-OD2 3.34Å; Q16-D438 PolarHBondContact NE2-OD2 2.71Å; Q16-G523 PolarHBondContact N-O 2.76Å; Q16-G523 PolarHBondContact O-N 2.87Å; Q16-G523 VanDerWaalsContact O-N 3.12Å; Q16-A525 HydrophobicContact CG-CB 4.47Å
17V98.6Very high80.3Confident2 Ų275.8 Ų75.81%0.01241%0.408CS..EExtended strand (participates in β ladder)trans-105.5126171.9-175.10000107.7L437 L471 L474 V520 I521 F522 W554 V555V17-L437 HydrophobicContact CB-CB 4.42Å; V17-L437 PolarHBondContact N-O 2.77Å; V17-L437 VanDerWaalsContact N-O 3.12Å; V17-L437 PolarHBondContact O-N 3.41Å; V17-L471 HydrophobicContact CB-CD2 4.28Å; V17-L471 HydrophobicContact CG1-CD2 4.25Å; V17-L471 HydrophobicContact CG2-CD2 4.16Å; V17-L474 HydrophobicContact CG1-CD1 4.27Å; V17-V520 HydrophobicContact CG1-CG1 4.2Å; V17-I521 CarbonylContact C-O 3.5Å; V17-I521 WeakPolarHBondContact CA-O 3.45Å; V17-F522 HydrophobicContact CG1-CE1 4.22Å; V17-F522 HydrophobicContact CG2-CD1 3.94Å; V17-F522 HydrophobicContact CG2-CE1 3.72Å; V17-W554 HydrophobicContact CG2-CH2 4.19Å; V17-W554 HydrophobicContact CG2-CZ2 3.99Å; V17-V555 HydrophobicContact CG2-CG2 3.76Å
18S98.8Very high83.4Confident16 Ų1670.9 Ų70.911%0.11238%0.382CS..EExtended strand (participates in β ladder)trans-124.5152.4175.2-54.50000111.2I435 T436 I521S18-I435 CarbonylContact C-O 3.46Å; S18-I435 WeakPolarHBondContact CA-O 3.5Å; S18-I435 WeakPolarHBondContact CB-O 3.38Å; S18-T436 WeakPolarHBondContact OG-CB 3.33Å; S18-T436 WeakPolarHBondContact OG-CG2 3.49Å; S18-T436 PolarHBondContact OG-OG1 2.78Å; S18-I521 PolarHBondContact N-O 3.26Å; S18-I521 PolarHBondContact O-N 3.46Å
19Y98.9Very high86.7Confident0 Ų063.6 Ų63.60%034%0.343CS..EExtended strand (participates in β ladder)trans-142.8159.6171.768.2-78.2000111.2I21 V393 A396 T434 I435 L470 L474 T518 P519Y19-I21 HydrophobicContact CD2-CG1 4.29Å; Y19-I21 HydrophobicContact CE2-CD1 4.25Å; Y19-I21 HydrophobicContact CE2-CG1 3.84Å; Y19-V393 WeakPolarHBondContact OH-CG1 3.34Å; Y19-V393 PolarHBondContact OH-O 2.83Å; Y19-A396 HydrophobicContact CD2-CB 3.97Å; Y19-A396 HydrophobicContact CE2-CB 3.53Å; Y19-T434 WeakPolarHBondContact O-CA 3.37Å; Y19-I435 HydrophobicContact CD1-CB 3.96Å; Y19-I435 HydrophobicContact CD1-CG2 4.38Å; Y19-I435 HydrophobicContact CE1-CB 3.37Å; Y19-I435 HydrophobicContact CE1-CG1 4.09Å; Y19-I435 HydrophobicContact CE1-CG2 3.46Å; Y19-I435 VanDerWaalsContact CE1-CG2 3.46Å; Y19-I435 HydrophobicContact CE2-CB 4.15Å; Y19-I435 HydrophobicContact CE2-CG1 3.97Å; Y19-I435 PolarHBondContact N-O 3.09Å; Y19-I435 PolarHBondContact O-N 3.33Å; Y19-L470 HydrophobicContact CE1-CD1 4.5Å; Y19-L470 HydrophobicContact CE1-CD2 3.57Å; Y19-L470 HydrophobicContact CE1-CG 4.43Å; Y19-L470 WeakPolarHBondContact OH-CD2 3.34Å; Y19-L474 HydrophobicContact CD1-CD1 3.95Å; Y19-L474 HydrophobicContact CD1-CD2 4.22Å; Y19-L474 HydrophobicContact CD2-CD2 4.33Å; Y19-L474 HydrophobicContact CE1-CD1 4.5Å; Y19-L474 HydrophobicContact CG-CD1 4.42Å; Y19-L474 HydrophobicContact CG-CD2 3.9Å; Y19-T518 HydrophobicContact CD2-CG2 3.89Å; Y19-T518 HydrophobicContact CG-CG2 4.32Å; Y19-P519 WeakPolarHBondContact CA-O 3.42Å; Y19-P519 VanDerWaalsContact CB-O 3.29Å; Y19-P519 WeakPolarHBondContact CB-O 3.48Å
20V98.9Very high89.7Confident13 Ų1360.1 Ų60.18%0.07931%0.306CS..EExtended strand (participates in β ladder)trans-116.3123.4-175.6-172.20000110R22 M432 L433 T434 P519 I521V20-R22 HydrophobicContact CB-CG 4.43Å; V20-R22 HydrophobicContact CG1-CB 4.24Å; V20-R22 HydrophobicContact CG1-CG 4.04Å; V20-R22 PolarHBondContact O-N 2.85Å; V20-M432 HydrophobicContact CG1-CB 4.04Å; V20-M432 HydrophobicContact CG1-CE 4.41Å; V20-M432 HydrophobicContact CG1-SD 4.42Å; V20-L433 WeakPolarHBondContact CA-O 3.29Å; V20-T434 HydrophobicContact CG2-CG2 4.25Å; V20-P519 HydrophobicContact CB-CG 4.33Å; V20-P519 PolarHBondContact N-O 3.23Å; V20-I521 HydrophobicContact CG2-CD1 4.27Å
21I98.8Very high92.8Very high7 Ų757 Ų574%0.03628%0.276CS..EExtended strand (participates in β ladder)trans-84.4109.7172.8-55.3176.9000108Y19 W391 A396 L433 I435Y19-I21 HydrophobicContact CD2-CG1 4.29Å; Y19-I21 HydrophobicContact CE2-CD1 4.25Å; Y19-I21 HydrophobicContact CE2-CG1 3.84Å; I21-W391 HydrophobicContact CG2-CE3 3.74Å; I21-W391 HydrophobicContact CG2-CZ3 3.88Å; I21-A396 HydrophobicContact CG1-CB 4.24Å; I21-L433 HydrophobicContact CB-CB 4.11Å; I21-L433 PolarHBondContact N-O 2.78Å; I21-I435 HydrophobicContact CD1-CD1 4.47Å; I21-I435 HydrophobicContact CD1-CG1 4.08Å; I21-I435 HydrophobicContact CG1-CG1 4.39Å
22R98.4Very high95.3Very high25 Ų2553.5 Ų53.59%0.09424%0.241CC..  trans-158.1169.9-17457.6171.2-77.3-166.6-8.1112.1V20 E24 E26 E72 M432 H517V20-R22 HydrophobicContact CB-CG 4.43Å; V20-R22 HydrophobicContact CG1-CB 4.24Å; V20-R22 HydrophobicContact CG1-CG 4.04Å; V20-R22 PolarHBondContact O-N 2.85Å; R22-E24 PolarHBondContact NH2-O 2.98Å; R22-E24 VanDerWaalsContact NH2-O 3.09Å; R22-E26 HydrophobicContact CB-CG 4.25Å; R22-E26 WeakPolarHBondContact CB-OE1 3.4Å; R22-E72 IonicContact CZ-OE1 2.85Å; R22-E72 IonicContact CZ-OE2 3.19Å; R22-E72 VanDerWaalsContact NH1-CD 3.32Å; R22-E72 IonicContact NH1-OE1 3.59Å; R22-E72 PolarHBondContact NH1-OE1 3.1Å; R22-E72 IonicContact NH1-OE2 3.55Å; R22-E72 PolarHBondContact NH1-OE2 2.7Å; R22-E72 IonicContact NH2-OE1 2.64Å; R22-E72 PolarHBondContact NH2-OE1 3.1Å; R22-E72 IonicContact NH2-OE2 2.76Å; R22-E72 PolarHBondContact NH2-OE2 2.92Å; R22-M432 HydrophobicContact CB-SD 4.08Å; R22-H517 PolarHBondContact O-NE2 2.89Å
23D98.1Very high97.1Very high109 Ų10942.3 Ų42.358%0.58320%0.198SC*.  trans-75.3159.2166.9-64.5-34.3000110.4V25 E26D23-V25 VanDerWaalsContact C-N 3.31Å; D23-V25 PolarHBondContact O-N 3.42Å; D23-E26 PolarHBondContact N-OE1 3.39Å; D23-E26 VanDerWaalsContact N-OE1 3.08Å
24E97.8Very high98.1Very high99 Ų9936.2 Ų36.246%0.46318%0.177SC..SBendtrans-57.9-46.5179.5-178.3168.9-154.800111R22 H517 R536R22-E24 PolarHBondContact NH2-O 2.98Å; R22-E24 VanDerWaalsContact NH2-O 3.09Å; E24-H517 WeakPolarHBondContact CA-CD2 3.47Å; E24-H517 HydrophobicContact CB-CB 3.98Å; E24-H517 HydrophobicContact CG-CB 3.8Å; E24-H517 PolarHBondContact N-CD2 2.83Å; E24-H517 PolarHBondContact N-NE2 3.27Å; E24-R536 IonicContact OE1-CZ 3.05Å; E24-R536 IonicContact OE1-NH1 3.1Å; E24-R536 PolarHBondContact OE1-NH1 3.23Å; E24-R536 IonicContact OE1-NH2 3.99Å; E24-R536 PolarHBondContact OE1-NH2 2.97Å
25V97.8Very high98.4Very high86 Ų8631 Ų3152%0.52115%0.154SC..  trans-115.9104.1178.3-176.10000110.5D23 K27D23-V25 VanDerWaalsContact C-N 3.31Å; D23-V25 PolarHBondContact O-N 3.42Å; V25-K27 VanDerWaalsContact C-N 3.31Å; V25-K27 PolarHBondContact O-N 3.39Å
26E98.3Very high98.5Very high11 Ų1129.8 Ų29.85%0.05115%0.146CC..  trans-84.777.2171.9-69-68.817300109.8R22 D23 Y28 R30 I53 R55 M432R22-E26 HydrophobicContact CB-CG 4.25Å; R22-E26 WeakPolarHBondContact CB-OE1 3.4Å; D23-E26 PolarHBondContact N-OE1 3.39Å; D23-E26 VanDerWaalsContact N-OE1 3.08Å; E26-Y28 VanDerWaalsContact C-N 3.28Å; E26-Y28 PolarHBondContact O-N 3.37Å; E26-R30 HydrophobicContact CB-CG 4.46Å; E26-R30 IonicContact OE1-NH1 3.25Å; E26-R30 PolarHBondContact OE1-NH1 2.74Å; E26-R30 VanDerWaalsContact OE2-CD 3.23Å; E26-R30 WeakPolarHBondContact OE2-CD 3.36Å; E26-R30 WeakPolarHBondContact OE2-CG 3.4Å; E26-R30 IonicContact OE2-CZ 3.31Å; E26-R30 IonicContact OE2-NE 3.67Å; E26-R30 IonicContact OE2-NH1 2.74Å; E26-R30 PolarHBondContact OE2-NH1 2.73Å; E26-I53 HydrophobicContact CB-CD1 4.18Å; E26-R55 PolarHBondContact O-NE 3.04Å; E26-R55 PolarHBondContact O-NH2 2.98Å; E26-M432 HydrophobicContact CG-SD 4.02Å
27K98.2Very high98.6Very high56 Ų5629.3 Ų29.324%0.24314%0.144CC..  trans-57.1-37.4-171.2-170.9-179.9-176177.50114V25 R55 W57 D65 Y67V25-K27 VanDerWaalsContact C-N 3.31Å; V25-K27 PolarHBondContact O-N 3.39Å; K27-R55 WeakPolarHBondContact O-CD 3.4Å; K27-R55 PolarHBondContact O-NE 3.26Å; K27-W57 VanDerWaalsContact O-CH2 3.32Å; K27-W57 WeakPolarHBondContact O-CH2 3.46Å; K27-D65 WeakPolarHBondContact CE-OD1 3.4Å; K27-D65 WeakPolarHBondContact CE-OD2 3.45Å; K27-D65 IonicContact NZ-OD1 3.47Å; K27-D65 PolarHBondContact NZ-OD1 3.05Å; K27-D65 IonicContact NZ-OD2 3.74Å; K27-D65 PolarHBondContact NZ-OD2 2.91Å; K27-Y67 HydrophobicContact CD-CD1 4.29Å; K27-Y67 HydrophobicContact CD-CG 4.22Å; K27-Y67 HydrophobicContact CG-CD1 3.83Å; K27-Y67 HydrophobicContact CG-CD2 3.65Å; K27-Y67 HydrophobicContact CG-CE1 4.2Å; K27-Y67 HydrophobicContact CG-CE2 4.05Å; K27-Y67 HydrophobicContact CG-CG 3.53Å; K27-Y67 WeakPolarHBondContact O-CD2 3.29Å
28Y98.6Very high98.6Very high73 Ų7330.2 Ų30.229%0.28615%0.149SC..SBendtrans-107.3153.8-178.4-53.9-69.7000110.9E26 R30 R55 W57 K362E26-Y28 VanDerWaalsContact C-N 3.28Å; E26-Y28 PolarHBondContact O-N 3.37Å; Y28-R30 PolarHBondContact O-N 3.15Å; Y28-R55 PolarHBondContact O-NH2 3.47Å; Y28-W57 HydrophobicContact CD1-CH2 4.04Å; Y28-W57 HydrophobicContact CD1-CZ3 4.34Å; Y28-K362 HydrophobicContact CD1-CB 4.03Å; Y28-K362 VanDerWaalsContact CD1-O 3.26Å; Y28-K362 WeakPolarHBondContact CD1-O 3.36Å; Y28-K362 HydrophobicContact CE1-CB 3.9Å
29N98.8Very high98.6Very high0 Ų029.7 Ų29.70%015%0.145CC..  trans-56.2130.2173.3-58.9-63.8000109.8V33 D51 R55 S323 G364N29-V33 HydrophobicContact CB-CG2 4.1Å; N29-V33 WeakPolarHBondContact ND2-CG2 3.28Å; N29-D51 WeakPolarHBondContact CA-OD2 3.46Å; N29-R55 PolarHBondContact OD1-NH1 3.48Å; N29-S323 PolarHBondContact ND2-O 3.19Å; N29-S323 WeakPolarHBondContact O-CB 3.37Å; N29-G364 WeakPolarHBondContact O-CA 3.08Å; N29-G364 PolarHBondContact O-N 2.8Å
30R98.7Very high98.3Very high40 Ų4033.9 Ų33.915%0.15117%0.172CC..SBendtrans-94.4-1.3177.9-64.1-60.4-61.5-80.6-5.6113E26 Y28 D51 A365 S366 M432E26-R30 HydrophobicContact CB-CG 4.46Å; E26-R30 IonicContact OE1-NH1 3.25Å; E26-R30 PolarHBondContact OE1-NH1 2.74Å; E26-R30 VanDerWaalsContact OE2-CD 3.23Å; E26-R30 WeakPolarHBondContact OE2-CD 3.36Å; E26-R30 WeakPolarHBondContact OE2-CG 3.4Å; E26-R30 IonicContact OE2-CZ 3.31Å; E26-R30 IonicContact OE2-NE 3.67Å; E26-R30 IonicContact OE2-NH1 2.74Å; E26-R30 PolarHBondContact OE2-NH1 2.73Å; Y28-R30 PolarHBondContact O-N 3.15Å; R30-D51 HydrophobicContact CB-CB 3.91Å; R30-D51 PolarHBondContact N-OD2 3.49Å; R30-A365 PolarHBondContact NE-O 3.35Å; R30-A365 PolarHBondContact NH2-O 2.67Å; R30-S366 VanDerWaalsContact O-CA 3.26Å; R30-S366 WeakPolarHBondContact O-CA 3.49Å; R30-S366 WeakPolarHBondContact O-CB 3.46Å; R30-S366 PolarHBondContact O-OG 3.07Å; R30-M432 HydrophobicContact CB-CG 3.98Å; R30-M432 HydrophobicContact CB-SD 4.35Å; R30-M432 HydrophobicContact CG-CG 4.11Å; R30-M432 HydrophobicContact CG-SD 4.1Å
31N98.8Very high98.2Very high25 Ų2537.2 Ų37.213%0.13420%0.201CC..SBendtrans-152.9179.8172.6-159-15.9000109.4R50 D51 S323 S366 K429N31-R50 HydrophobicContact CB-CB 3.82Å; N31-D51 HydrophobicContact CB-CB 4.25Å; N31-S323 WeakPolarHBondContact O-CA 3.34Å; N31-S366 WeakPolarHBondContact CA-OG 3.31Å; N31-K429 PolarHBondContact ND2-O 2.85Å
32G98.7Very high98Very high0 Ų039.9 Ų39.90%022%0.215CC..  trans-55.6160.1179.800000114.3R50 T321 K322G32-R50 VanDerWaalsContact O-CB 3.27Å; G32-R50 WeakPolarHBondContact O-CB 3.44Å; G32-R50 WeakPolarHBondContact O-CG 3.39Å; G32-R50 PolarHBondContact O-N 2.95Å; G32-T321 WeakPolarHBondContact CA-O 3.4Å; G32-K322 WeakPolarHBondContact CA-O 3.12Å
33V98.9Very high98Very high0 Ų041.2 Ų41.20%022%0.224CC..EExtended strand (participates in β ladder)trans-109.8117.8-176.71740000109.8N29 A35 L36 T47 A48 S319 T320 V325N29-V33 HydrophobicContact CB-CG2 4.1Å; N29-V33 WeakPolarHBondContact ND2-CG2 3.28Å; V33-A35 WeakPolarHBondContact CG1-O 3.41Å; V33-L36 HydrophobicContact CG1-CD2 3.86Å; V33-T47 HydrophobicContact CG1-CG2 4.26Å; V33-A48 CarbonylContact C-O 3.52Å; V33-S319 WeakPolarHBondContact O-CB 3.29Å; V33-S319 PolarHBondContact O-OG 2.96Å; V33-T320 PolarHBondContact N-O 3.08Å; V33-T320 VanDerWaalsContact N-O 3.15Å; V33-V325 HydrophobicContact CB-CG2 4.15Å; V33-V325 HydrophobicContact CG1-CG2 4.3Å; V33-V325 HydrophobicContact CG2-CG2 3.8Å
34N98.9Very high98Very high16 Ų1638.8 Ų38.89%0.08621%0.206CC..EExtended strand (participates in β ladder)trans-83.5-29.9-173.6-73.9-36.7000113.8A48 R50 V78 N79 K303N34-A48 PolarHBondContact N-O 3.22Å; N34-R50 VanDerWaalsContact ND2-CG 3.31Å; N34-R50 WeakPolarHBondContact ND2-CG 3.13Å; N34-R50 WeakPolarHBondContact OD1-CG 3.32Å; N34-R50 PolarHBondContact OD1-NE 3.03Å; N34-R50 PolarHBondContact OD1-NH2 3.03Å; N34-V78 VanDerWaalsContact CB-O 3.29Å; N34-V78 WeakPolarHBondContact CB-O 3.46Å; N34-V78 PolarHBondContact ND2-O 2.99Å; N34-N79 WeakPolarHBondContact CB-O 3.17Å; N34-K303 WeakPolarHBondContact O-CB 3.34Å
35A98.9Very high98Very high0 Ų034 Ų340%018%0.184CC..EExtended strand (participates in β ladder)trans-150.7157.2-176.800000112.5V33 A48 D80 I81V33-A35 WeakPolarHBondContact CG1-O 3.41Å; A35-A48 HydrophobicContact CB-CB 4.04Å; A35-A48 PolarHBondContact O-N 2.88Å; A35-D80 WeakPolarHBondContact CB-OD1 3.07Å; A35-I81 HydrophobicContact CB-CG1 3.94Å
36L98.9Very high98.1Very high1 Ų130 Ų301%0.00516%0.159CC..EExtended strand (participates in β ladder)trans-133.5144.5-176.4-62177.3000109.4V33 L45 F46 T47 E305 W317 V325V33-L36 HydrophobicContact CG1-CD2 3.86Å; L36-L45 HydrophobicContact CB-CD1 4.41Å; L36-L45 HydrophobicContact CD2-CD1 4.47Å; L36-L45 HydrophobicContact CD2-CD2 4.39Å; L36-F46 WeakPolarHBondContact CA-O 3.28Å; L36-T47 HydrophobicContact CD2-CG2 3.71Å; L36-E305 HydrophobicContact CB-CB 3.84Å; L36-E305 HydrophobicContact CD1-CB 4.38Å; L36-W317 HydrophobicContact CD1-CB 3.95Å; L36-V325 HydrophobicContact CD1-CG1 4.32Å; L36-V325 HydrophobicContact CD2-CG1 3.99Å
37Q98.8Very high98.1Very high36 Ų3629.4 Ų29.417%0.16816%0.157CC..EExtended strand (participates in β ladder)trans-139.1135.2166.7-72.2-69-76.100109.2F46 I81 L83Q37-F46 HydrophobicContact CB-CB 4.33Å; Q37-F46 PolarHBondContact N-O 2.88Å; Q37-F46 VanDerWaalsContact N-O 3.13Å; Q37-F46 PolarHBondContact O-N 2.84Å; Q37-I81 HydrophobicContact CB-CD1 4.19Å; Q37-I81 HydrophobicContact CG-CB 4.43Å; Q37-I81 HydrophobicContact CG-CD1 4.02Å; Q37-I81 HydrophobicContact CG-CG1 3.89Å; Q37-I81 VanDerWaalsContact CG-O 3.28Å; Q37-I81 WeakPolarHBondContact CG-O 3.27Å; Q37-L83 HydrophobicContact CB-CB 3.99Å; Q37-L83 HydrophobicContact CG-CB 4.22Å; Q37-L83 VanDerWaalsContact OE1-N 3.07Å
38L98.5Very high98.1Very high22 Ų2226.8 Ų26.812%0.11515%0.145CC..EExtended strand (participates in β ladder)trans-108.3125.3178.6-17468.1000109.9P40 L45 V59 E305 D307L38-P40 VanDerWaalsContact O-CD 3.29Å; L38-P40 WeakPolarHBondContact O-CD 3.45Å; L38-L45 HydrophobicContact CB-CD1 4.49Å; L38-L45 HydrophobicContact CD1-CB 4.4Å; L38-L45 HydrophobicContact CD1-CD1 4.24Å; L38-V59 HydrophobicContact CD1-CG1 4.11Å; L38-V59 HydrophobicContact CD1-CG2 4.29Å; L38-E305 HydrophobicContact CB-CG 3.98Å; L38-D307 HydrophobicContact CD2-CB 4.46Å
39D98.1Very high98.1Very high4 Ų423.3 Ų23.32%0.02113%0.132CC..EExtended strand (participates in β ladder)trans-91.6105.4165.7-173.7-22.9000108.9A41 L42 N43 R44 F46 L83D39-A41 VanDerWaalsContact C-N 3.31Å; D39-A41 WeakPolarHBondContact OD1-CA 3.39Å; D39-A41 WeakPolarHBondContact OD1-CB 3.15Å; D39-A41 PolarHBondContact OD1-N 2.85Å; D39-L42 PolarHBondContact OD1-N 3Å; D39-N43 VanDerWaalsContact O-CA 3.28Å; D39-N43 WeakPolarHBondContact O-CA 3.45Å; D39-N43 PolarHBondContact O-N 2.75Å; D39-R44 HydrophobicContact CB-CB 4.14Å; D39-R44 PolarHBondContact N-O 3.33Å; D39-R44 PolarHBondContact O-N 2.91Å; D39-F46 HydrophobicContact CB-CE2 4.25Å; D39-L83 HydrophobicContact CB-CD2 3.64Å
40P94.1Very high98.1Very high89 Ų8925.4 Ų25.458%0.57814%0.14SC*.THydrogen-bonded Turntrans-74-22.8179.531.1-35.7000112.7L38L38-P40 VanDerWaalsContact O-CD 3.29Å; L38-P40 WeakPolarHBondContact O-CD 3.45Å
41A95.4Very high98.1Very high82 Ų8223.5 Ų23.568%0.67813%0.133SC*.THydrogen-bonded Turntrans-75.3-40.6-178.600000111.1D39D39-A41 VanDerWaalsContact C-N 3.31Å; D39-A41 WeakPolarHBondContact OD1-CA 3.39Å; D39-A41 WeakPolarHBondContact OD1-CB 3.15Å; D39-A41 PolarHBondContact OD1-N 2.85Å
42L96.3Very high98.1Very high64 Ų6423 Ų2334%0.33513%0.131SC..THydrogen-bonded Turntrans-98.4-3.1179.6-60.9-177.9000113.8D39 R44D39-L42 PolarHBondContact OD1-N 3Å; L42-R44 VanDerWaalsContact C-N 3.31Å; L42-R44 HydrophobicContact CB-CB 4.49Å; L42-R44 HydrophobicContact CB-CG 3.84Å; L42-R44 PolarHBondContact O-N 3.41Å
43N96.8Very high98.2Very high52 Ų5223 Ų2328%0.27813%0.131SC..THydrogen-bonded Turntrans50.553.3-171.1-72.8-56.3000111D39 V59 Y60D39-N43 VanDerWaalsContact O-CA 3.28Å; D39-N43 WeakPolarHBondContact O-CA 3.45Å; D39-N43 PolarHBondContact O-N 2.75Å; N43-V59 HydrophobicContact CB-CG2 3.76Å; N43-V59 WeakPolarHBondContact O-CG2 3.47Å; N43-V59 PolarHBondContact O-N 3.31Å; N43-Y60 HydrophobicContact CB-CD2 4.24Å; N43-Y60 HydrophobicContact CB-CE1 4.19Å; N43-Y60 HydrophobicContact CB-CE2 3.74Å; N43-Y60 VanDerWaalsContact ND2-CZ 3.29Å; N43-Y60 PolarHBondContact ND2-OH 2.88Å
44R98Very high98.2Very high58 Ų5823.1 Ų23.122%0.21913%0.132CC..EExtended strand (participates in β ladder)trans-118.8131.7179.7-66176.1-179.3-172.6-1.5111.6D39 L42 F46 I56 W57 I68D39-R44 HydrophobicContact CB-CB 4.14Å; D39-R44 PolarHBondContact N-O 3.33Å; D39-R44 PolarHBondContact O-N 2.91Å; L42-R44 VanDerWaalsContact C-N 3.31Å; L42-R44 HydrophobicContact CB-CB 4.49Å; L42-R44 HydrophobicContact CB-CG 3.84Å; L42-R44 PolarHBondContact O-N 3.41Å; R44-F46 HydrophobicContact CB-CE2 4.21Å; R44-I56 HydrophobicContact CB-CG2 4.17Å; R44-I56 HydrophobicContact CG-CG2 4.27Å; R44-W57 CarbonylContact C-O 3.58Å; R44-W57 WeakPolarHBondContact CA-O 3.47Å; R44-I68 HydrophobicContact CG-CD1 4.01Å
45L98.8Very high98.2Very high0 Ų022.3 Ų22.30%013%0.128CC..EExtended strand (participates in β ladder)trans-101.1133.6168.9-176.174.8000109L36 L38 T47 W57 V59 W317 V325 I361L36-L45 HydrophobicContact CB-CD1 4.41Å; L36-L45 HydrophobicContact CD2-CD1 4.47Å; L36-L45 HydrophobicContact CD2-CD2 4.39Å; L38-L45 HydrophobicContact CB-CD1 4.49Å; L38-L45 HydrophobicContact CD1-CB 4.4Å; L38-L45 HydrophobicContact CD1-CD1 4.24Å; L45-T47 HydrophobicContact CD2-CG2 4.15Å; L45-T47 HydrophobicContact CG-CG2 4.43Å; L45-W57 HydrophobicContact CB-CB 4.33Å; L45-W57 PolarHBondContact N-O 3.04Å; L45-W57 PolarHBondContact O-N 3.4Å; L45-V59 HydrophobicContact CB-CG1 3.64Å; L45-W317 HydrophobicContact CD1-CB 4.46Å; L45-W317 HydrophobicContact CD1-CD2 4.38Å; L45-W317 HydrophobicContact CD1-CG 4.17Å; L45-W317 HydrophobicContact CD2-CD2 3.83Å; L45-W317 HydrophobicContact CD2-CE3 3.65Å; L45-W317 HydrophobicContact CD2-CG 4.38Å; L45-W317 HydrophobicContact CD2-CH2 4.35Å; L45-W317 HydrophobicContact CD2-CZ3 3.92Å; L45-V325 HydrophobicContact CD2-CG1 4.19Å; L45-I361 HydrophobicContact CD2-CD1 3.58Å
46F98.9Very high98.1Very high0 Ų022.4 Ų22.40%013%0.128CC..EExtended strand (participates in β ladder)trans-103.4130.4170.2-63.8-97.7000109.1L36 Q37 D39 R44 R55 I56 M71 I81 L83 L90 A104L36-F46 WeakPolarHBondContact CA-O 3.28Å; Q37-F46 HydrophobicContact CB-CB 4.33Å; Q37-F46 PolarHBondContact N-O 2.88Å; Q37-F46 VanDerWaalsContact N-O 3.13Å; Q37-F46 PolarHBondContact O-N 2.84Å; D39-F46 HydrophobicContact CB-CE2 4.25Å; R44-F46 HydrophobicContact CB-CE2 4.21Å; F46-R55 WeakPolarHBondContact CA-O 3.12Å; F46-I56 HydrophobicContact CD1-CD1 4.43Å; F46-I56 HydrophobicContact CD1-CG1 3.87Å; F46-I56 HydrophobicContact CD1-CG2 4.43Å; F46-I56 HydrophobicContact CE1-CB 4.38Å; F46-I56 HydrophobicContact CE1-CD1 3.72Å; F46-I56 HydrophobicContact CE1-CG1 3.64Å; F46-I56 HydrophobicContact CE1-CG2 4.02Å; F46-I56 HydrophobicContact CZ-CD1 4.46Å; F46-I56 HydrophobicContact CZ-CG2 4.18Å; F46-M71 HydrophobicContact CD1-SD 4.35Å; F46-M71 HydrophobicContact CE1-SD 4.28Å; F46-I81 HydrophobicContact CB-CD1 3.76Å; F46-L83 HydrophobicContact CD2-CD1 4.3Å; F46-L83 HydrophobicContact CD2-CD2 4.35Å; F46-L83 HydrophobicContact CE2-CD1 3.83Å; F46-L83 HydrophobicContact CE2-CD2 4.01Å; F46-L83 HydrophobicContact CZ-CD1 4.08Å; F46-L90 HydrophobicContact CB-CD1 4.05Å; F46-L90 HydrophobicContact CD1-CD1 3.53Å; F46-L90 HydrophobicContact CE1-CD1 4.06Å; F46-L90 HydrophobicContact CG-CD1 3.79Å; F46-A104 HydrophobicContact CE1-CB 4.12Å; F46-A104 HydrophobicContact CZ-CB 4Å
47T98.9Very high98.1Very high0 Ų022.4 Ų22.40%013%0.128CC..EExtended strand (participates in β ladder)trans-115.4126.1175.859.60000110.2V33 L36 L45 I54 R55 W57 V325V33-T47 HydrophobicContact CG1-CG2 4.26Å; L36-T47 HydrophobicContact CD2-CG2 3.71Å; L45-T47 HydrophobicContact CD2-CG2 4.15Å; L45-T47 HydrophobicContact CG-CG2 4.43Å; T47-I54 VanDerWaalsContact O-CA 3.3Å; T47-I54 WeakPolarHBondContact O-CA 3.27Å; T47-R55 PolarHBondContact N-O 2.79Å; T47-R55 PolarHBondContact O-N 2.9Å; T47-W57 VanDerWaalsContact CG2-NE1 3.31Å; T47-W57 PolarHBondContact OG1-NE1 3.01Å; T47-V325 HydrophobicContact CG2-CG2 3.99Å
48A98.9Very high98.1Very high0 Ų020.9 Ų20.90%012%0.121CC..EExtended strand (participates in β ladder)trans-93.2102.6173.900000110.7V33 N34 A35 V78 I81V33-A48 CarbonylContact C-O 3.52Å; N34-A48 PolarHBondContact N-O 3.22Å; A35-A48 HydrophobicContact CB-CB 4.04Å; A35-A48 PolarHBondContact O-N 2.88Å; A48-V78 HydrophobicContact CB-CB 3.95Å; A48-V78 HydrophobicContact CB-CG1 3.69Å; A48-I81 HydrophobicContact CB-CB 4.49Å; A48-I81 HydrophobicContact CB-CD1 4.03Å; A48-I81 HydrophobicContact CB-CG1 3.9Å; A48-I81 HydrophobicContact CB-CG2 3.84Å
49G98.8Very high97.9Very high0 Ų020.4 Ų20.40%012%0.119CC..EExtended strand (participates in β ladder)trans-80.5145-175.700000113.8D51 S52 I53 V78G49-D51 WeakPolarHBondContact CA-OD1 3.31Å; G49-D51 PolarHBondContact O-N 2.97Å; G49-S52 PolarHBondContact O-N 2.98Å; G49-I53 PolarHBondContact N-O 2.79Å; G49-V78 PolarHBondContact O-N 3.38Å
50R98.9Very high97.7Very high44 Ų4426 Ų2617%0.16614%0.141CC..THydrogen-bonded Turntrans-65.2-13.2161.6-73.2-178.8-179.8-170.8-2.8112.1N31 G32 N34 S52 W77 L302N31-R50 HydrophobicContact CB-CB 3.82Å; G32-R50 VanDerWaalsContact O-CB 3.27Å; G32-R50 WeakPolarHBondContact O-CB 3.44Å; G32-R50 WeakPolarHBondContact O-CG 3.39Å; G32-R50 PolarHBondContact O-N 2.95Å; N34-R50 VanDerWaalsContact ND2-CG 3.31Å; N34-R50 WeakPolarHBondContact ND2-CG 3.13Å; N34-R50 WeakPolarHBondContact OD1-CG 3.32Å; N34-R50 PolarHBondContact OD1-NE 3.03Å; N34-R50 PolarHBondContact OD1-NH2 3.03Å; R50-S52 PolarHBondContact O-N 3.4Å; R50-W77 HydrophobicContact CB-CD2 4.16Å; R50-W77 HydrophobicContact CB-CG 3.99Å; R50-W77 HydrophobicContact CG-CD2 3.82Å; R50-W77 HydrophobicContact CG-CE3 4.18Å; R50-W77 HydrophobicContact CG-CG 3.98Å; R50-W77 PolarHBondContact O-NE1 3Å; R50-L302 VanDerWaalsContact NH2-CD1 3.32Å
51D98.8Very high97Very high0 Ų027.1 Ų27.10%014%0.138CC..THydrogen-bonded Turntrans-80.814.1173.467.8-9.5000114N29 R30 N31 G49 I53 R55 T430 M432N29-D51 WeakPolarHBondContact CA-OD2 3.46Å; R30-D51 HydrophobicContact CB-CB 3.91Å; R30-D51 PolarHBondContact N-OD2 3.49Å; N31-D51 HydrophobicContact CB-CB 4.25Å; G49-D51 WeakPolarHBondContact CA-OD1 3.31Å; G49-D51 PolarHBondContact O-N 2.97Å; D51-I53 PolarHBondContact O-N 2.92Å; D51-I53 PolarHBondContact OD1-N 2.9Å; D51-R55 IonicContact OD1-NH1 3.83Å; D51-R55 PolarHBondContact OD1-NH1 2.89Å; D51-R55 IonicContact OD2-CZ 3.26Å; D51-R55 IonicContact OD2-NH1 3.68Å; D51-R55 PolarHBondContact OD2-NH1 3.33Å; D51-R55 IonicContact OD2-NH2 3.11Å; D51-R55 PolarHBondContact OD2-NH2 3.45Å; D51-T430 VanDerWaalsContact CA-O 3.28Å; D51-T430 WeakPolarHBondContact CA-O 3.37Å; D51-T430 WeakPolarHBondContact CB-O 3.37Å; D51-M432 HydrophobicContact CB-CE 4.16Å; D51-M432 WeakPolarHBondContact O-CE 3.5Å
52S98.8Very high96.3Very high15 Ų1532.4 Ų32.411%0.10515%0.149CC..SBendtrans70.35.1-178.791.80000116.3G49 R50 H74 D76G49-S52 PolarHBondContact O-N 2.98Å; R50-S52 PolarHBondContact O-N 3.4Å; S52-H74 WeakPolarHBondContact CB-O 3.45Å; S52-H74 PolarHBondContact OG-O 3.16Å; S52-D76 VanDerWaalsContact CA-O 3.28Å; S52-D76 WeakPolarHBondContact CA-O 3.45Å; S52-D76 WeakPolarHBondContact CB-O 3.37Å
53I98.9Very high95.7Very high1 Ų134.6 Ų34.61%0.00516%0.156CC..EExtended strand (participates in β ladder)trans-111.9135.6-174.8-58.8169.7000110.2E26 G49 D51 R55 E72E26-I53 HydrophobicContact CB-CD1 4.18Å; G49-I53 PolarHBondContact N-O 2.79Å; D51-I53 PolarHBondContact O-N 2.92Å; D51-I53 PolarHBondContact OD1-N 2.9Å; I53-R55 HydrophobicContact CG2-CG 3.91Å; I53-E72 HydrophobicContact CD1-CG 4.38Å; I53-E72 HydrophobicContact CG1-CG 4.1Å; I53-E72 HydrophobicContact CG2-CG 4.03Å
54I98.9Very high95.2Very high1 Ų141.9 Ų41.91%0.00519%0.188CC..EExtended strand (participates in β ladder)trans-95.2131.7167.4-60.5164000107.7T47 M71 V78 I81 L90 W102T47-I54 VanDerWaalsContact O-CA 3.3Å; T47-I54 WeakPolarHBondContact O-CA 3.27Å; I54-M71 HydrophobicContact CB-CB 4.06Å; I54-M71 HydrophobicContact CB-SD 4.49Å; I54-M71 HydrophobicContact CG2-SD 3.95Å; I54-M71 PolarHBondContact N-O 3.33Å; I54-M71 PolarHBondContact O-N 2.94Å; I54-V78 HydrophobicContact CD1-CG1 4.07Å; I54-V78 HydrophobicContact CG1-CB 4.45Å; I54-V78 HydrophobicContact CG1-CG1 4Å; I54-V78 HydrophobicContact CG1-CG2 4.13Å; I54-I81 HydrophobicContact CD1-CG2 3.9Å; I54-I81 HydrophobicContact CG1-CG2 4.32Å; I54-L90 HydrophobicContact CD1-CD2 3.92Å; I54-W102 HydrophobicContact CD1-CZ2 4.1Å
55R98.9Very high95Very high0 Ų042.5 Ų42.50%020%0.196CC..EExtended strand (participates in β ladder)trans-119.8147.1179.7-64179.8179.674.30.6111.7E26 K27 Y28 N29 F46 T47 D51 I53 W57 A69E26-R55 PolarHBondContact O-NE 3.04Å; E26-R55 PolarHBondContact O-NH2 2.98Å; K27-R55 WeakPolarHBondContact O-CD 3.4Å; K27-R55 PolarHBondContact O-NE 3.26Å; Y28-R55 PolarHBondContact O-NH2 3.47Å; N29-R55 PolarHBondContact OD1-NH1 3.48Å; F46-R55 WeakPolarHBondContact CA-O 3.12Å; T47-R55 PolarHBondContact N-O 2.79Å; T47-R55 PolarHBondContact O-N 2.9Å; D51-R55 IonicContact OD1-NH1 3.83Å; D51-R55 PolarHBondContact OD1-NH1 2.89Å; D51-R55 IonicContact OD2-CZ 3.26Å; D51-R55 IonicContact OD2-NH1 3.68Å; D51-R55 PolarHBondContact OD2-NH1 3.33Å; D51-R55 IonicContact OD2-NH2 3.11Å; D51-R55 PolarHBondContact OD2-NH2 3.45Å; I53-R55 HydrophobicContact CG2-CG 3.91Å; R55-W57 HydrophobicContact CB-CZ2 3.76Å; R55-W57 VanDerWaalsContact CD-CZ2 3.5Å; R55-W57 HydrophobicContact CG-CZ2 4.28Å; R55-A69 WeakPolarHBondContact CA-O 3.36Å
56I98.8Very high94.9Very high2 Ų243.4 Ų43.41%0.0120%0.202CC..EExtended strand (participates in β ladder)trans-108.3128.3177.6-42.8-177.4000108.7R44 F46 I68 A69 M71R44-I56 HydrophobicContact CB-CG2 4.17Å; R44-I56 HydrophobicContact CG-CG2 4.27Å; F46-I56 HydrophobicContact CD1-CD1 4.43Å; F46-I56 HydrophobicContact CD1-CG1 3.87Å; F46-I56 HydrophobicContact CD1-CG2 4.43Å; F46-I56 HydrophobicContact CE1-CB 4.38Å; F46-I56 HydrophobicContact CE1-CD1 3.72Å; F46-I56 HydrophobicContact CE1-CG1 3.64Å; F46-I56 HydrophobicContact CE1-CG2 4.02Å; F46-I56 HydrophobicContact CZ-CD1 4.46Å; F46-I56 HydrophobicContact CZ-CG2 4.18Å; I56-I68 HydrophobicContact CB-CB 4.16Å; I56-I68 HydrophobicContact CG2-CB 4.26Å; I56-I68 HydrophobicContact CG2-CD1 4.08Å; I56-I68 WeakPolarHBondContact O-CB 3.42Å; I56-I68 PolarHBondContact O-N 3.03Å; I56-A69 HydrophobicContact CD1-CB 4.25Å; I56-A69 HydrophobicContact CG1-CB 4.47Å; I56-A69 PolarHBondContact N-O 3.29Å; I56-M71 HydrophobicContact CD1-CG 4.34Å; I56-M71 HydrophobicContact CD1-SD 3.87Å; I56-M71 HydrophobicContact CG1-CG 4.44Å; I56-M71 HydrophobicContact CG1-SD 3.94Å
57W98.6Very high94.9Very high0 Ų045.9 Ų45.90%021%0.212CC..EExtended strand (participates in β ladder)trans-125142.7-177.9-49.192000110.7K27 Y28 R44 L45 T47 R55 P66 Y67 I361K27-W57 VanDerWaalsContact O-CH2 3.32Å; K27-W57 WeakPolarHBondContact O-CH2 3.46Å; Y28-W57 HydrophobicContact CD1-CH2 4.04Å; Y28-W57 HydrophobicContact CD1-CZ3 4.34Å; R44-W57 CarbonylContact C-O 3.58Å; R44-W57 WeakPolarHBondContact CA-O 3.47Å; L45-W57 HydrophobicContact CB-CB 4.33Å; L45-W57 PolarHBondContact N-O 3.04Å; L45-W57 PolarHBondContact O-N 3.4Å; T47-W57 VanDerWaalsContact CG2-NE1 3.31Å; T47-W57 PolarHBondContact OG1-NE1 3.01Å; R55-W57 HydrophobicContact CB-CZ2 3.76Å; R55-W57 VanDerWaalsContact CD-CZ2 3.5Å; R55-W57 HydrophobicContact CG-CZ2 4.28Å; W57-P66 CarbonylContact C-O 3.52Å; W57-P66 VanDerWaalsContact CA-O 3.24Å; W57-P66 WeakPolarHBondContact CA-O 3.44Å; W57-P66 HydrophobicContact CE3-CB 4.31Å; W57-P66 HydrophobicContact CE3-CG 4.08Å; W57-P66 HydrophobicContact CZ3-CG 4.48Å; W57-Y67 HydrophobicContact CH2-CD2 4.26Å; W57-Y67 HydrophobicContact CZ3-CD2 4.07Å; W57-Y67 HydrophobicContact CZ3-CG 4.47Å; W57-I361 HydrophobicContact CB-CD1 3.91Å; W57-I361 HydrophobicContact CD2-CD1 4.13Å; W57-I361 HydrophobicContact CD2-CG2 3.7Å; W57-I361 HydrophobicContact CE3-CG2 3.66Å; W57-I361 HydrophobicContact CG-CD1 3.76Å; W57-I361 HydrophobicContact CG-CG2 4.45Å; W57-I361 HydrophobicContact CH2-CG2 3.72Å; W57-I361 HydrophobicContact CZ2-CG2 3.74Å; W57-I361 HydrophobicContact CZ3-CG2 3.68Å
58S97.6Very high94.8Very high4 Ų448.9 Ų48.93%0.02823%0.227CC..EExtended strand (participates in β ladder)trans-81.9131.5166.9-162.40000109.7Y60 K63 P66S58-Y60 WeakPolarHBondContact OG-CD2 3.4Å; S58-K63 PolarHBondContact OG-NZ 3Å; S58-P66 PolarHBondContact N-O 2.81Å; S58-P66 WeakPolarHBondContact O-CB 3.38Å
59V95.8Very high94.8Very high12 Ų1250.2 Ų50.27%0.07324%0.238CC..  trans-96.89.5177.9-55.80000113.8L38 N43 L45 Q61 W317 Q359L38-V59 HydrophobicContact CD1-CG1 4.11Å; L38-V59 HydrophobicContact CD1-CG2 4.29Å; N43-V59 HydrophobicContact CB-CG2 3.76Å; N43-V59 WeakPolarHBondContact O-CG2 3.47Å; N43-V59 PolarHBondContact O-N 3.31Å; L45-V59 HydrophobicContact CB-CG1 3.64Å; V59-Q61 PolarHBondContact O-N 3.19Å; V59-W317 HydrophobicContact CB-CZ2 3.83Å; V59-W317 HydrophobicContact CG1-CH2 4.18Å; V59-W317 HydrophobicContact CG1-CZ2 3.44Å; V59-W317 VanDerWaalsContact CG1-CZ2 3.44Å; V59-Q359 PolarHBondContact O-OE1 2.95Å
60Y92.4Very high94.8Very high121 Ų12151.4 Ų51.448%0.47525%0.247SC..  trans-68.6114.9170.9-70.4-67.5000110.1N43 S58 Q62 K63N43-Y60 HydrophobicContact CB-CD2 4.24Å; N43-Y60 HydrophobicContact CB-CE1 4.19Å; N43-Y60 HydrophobicContact CB-CE2 3.74Å; N43-Y60 VanDerWaalsContact ND2-CZ 3.29Å; N43-Y60 PolarHBondContact ND2-OH 2.88Å; S58-Y60 WeakPolarHBondContact OG-CD2 3.4Å; Y60-Q62 PolarHBondContact O-N 3.45Å; Y60-Q62 VanDerWaalsContact O-N 3.11Å; Y60-K63 PolarHBondContact O-N 3.4Å; Y60-K63 VanDerWaalsContact O-N 3.13Å
61Q79.2Confident94.7Very high113 Ų11349.4 Ų49.453%0.52824%0.239SC..THydrogen-bonded Turntrans-59.2-25.6-176.1-69.6176.2-3.100114.1V59 K63 E358V59-Q61 PolarHBondContact O-N 3.19Å; Q61-K63 VanDerWaalsContact C-N 3.29Å; Q61-K63 PolarHBondContact O-N 3.43Å; Q61-E358 PolarHBondContact NE2-OE1 2.91Å
62Q82.2Confident94.7Very high194 Ų19451.9 Ų51.991%0.90725%0.25SS*.THydrogen-bonded Turntrans-76-13.8-178.6-64.8178.2-3.600113.7Y60 Q64Y60-Q62 PolarHBondContact O-N 3.45Å; Y60-Q62 VanDerWaalsContact O-N 3.11Å; Q62-Q64 PolarHBondContact O-N 2.82Å
63K83.8Confident94.7Very high110 Ų11054 Ų5448%0.47826%0.258SS..  trans-78.6123.3177.8-79-170.7175.6179.90110.8S58 Y60 Q61 D65S58-K63 PolarHBondContact OG-NZ 3Å; Y60-K63 PolarHBondContact O-N 3.4Å; Y60-K63 VanDerWaalsContact O-N 3.13Å; Q61-K63 VanDerWaalsContact C-N 3.29Å; Q61-K63 PolarHBondContact O-N 3.43Å; K63-D65 VanDerWaalsContact C-N 3.29Å; K63-D65 PolarHBondContact O-N 3.22Å
64Q85.7Confident94.7Very high205 Ų20554 Ų5496%0.95826%0.259SS*.SBendtrans-64.4-34.8174.2-67.6-178.91.600112.5Q62Q62-Q64 PolarHBondContact O-N 2.82Å
65D93.6Very high94.7Very high70 Ų7054.7 Ų54.737%0.37426%0.263SS..  trans-119.2107.5176.9-177.520.7000110.4K27 K63 Y67K27-D65 WeakPolarHBondContact CE-OD1 3.4Å; K27-D65 WeakPolarHBondContact CE-OD2 3.45Å; K27-D65 IonicContact NZ-OD1 3.47Å; K27-D65 PolarHBondContact NZ-OD1 3.05Å; K27-D65 IonicContact NZ-OD2 3.74Å; K27-D65 PolarHBondContact NZ-OD2 2.91Å; K63-D65 VanDerWaalsContact C-N 3.29Å; K63-D65 PolarHBondContact O-N 3.22Å; D65-Y67 VanDerWaalsContact C-N 3.31Å; D65-Y67 PolarHBondContact O-N 2.75Å; D65-Y67 PolarHBondContact OD1-N 3.41Å
66P96.3Very high94.7Very high20 Ų2055.3 Ų55.313%0.1327%0.266CS..  trans-79.1-11.6-177.931.1-34.2000113W57 S58W57-P66 CarbonylContact C-O 3.52Å; W57-P66 VanDerWaalsContact CA-O 3.24Å; W57-P66 WeakPolarHBondContact CA-O 3.44Å; W57-P66 HydrophobicContact CE3-CB 4.31Å; W57-P66 HydrophobicContact CE3-CG 4.08Å; W57-P66 HydrophobicContact CZ3-CG 4.48Å; S58-P66 PolarHBondContact N-O 2.81Å; S58-P66 WeakPolarHBondContact O-CB 3.38Å
67Y98.1Very high94.7Very high52 Ų5258.5 Ų58.520%0.20428%0.278CS..EExtended strand (participates in β ladder)trans-65.9137.1-175.7175.8-100.1000112.4K27 W57 D65 S70K27-Y67 HydrophobicContact CD-CD1 4.29Å; K27-Y67 HydrophobicContact CD-CG 4.22Å; K27-Y67 HydrophobicContact CG-CD1 3.83Å; K27-Y67 HydrophobicContact CG-CD2 3.65Å; K27-Y67 HydrophobicContact CG-CE1 4.2Å; K27-Y67 HydrophobicContact CG-CE2 4.05Å; K27-Y67 HydrophobicContact CG-CG 3.53Å; K27-Y67 WeakPolarHBondContact O-CD2 3.29Å; W57-Y67 HydrophobicContact CH2-CD2 4.26Å; W57-Y67 HydrophobicContact CZ3-CD2 4.07Å; W57-Y67 HydrophobicContact CZ3-CG 4.47Å; D65-Y67 VanDerWaalsContact C-N 3.31Å; D65-Y67 PolarHBondContact O-N 2.75Å; D65-Y67 PolarHBondContact OD1-N 3.41Å; Y67-S70 PolarHBondContact OH-N 3.38Å; Y67-S70 PolarHBondContact OH-OG 2.9Å
68I97.8Very high94.7Very high62 Ų6258.5 Ų58.532%0.31828%0.278SS..EExtended strand (participates in β ladder)trans-116.1-57.3174.7-59.7175000110.6R44 I56R44-I68 HydrophobicContact CG-CD1 4.01Å; I56-I68 HydrophobicContact CB-CB 4.16Å; I56-I68 HydrophobicContact CG2-CB 4.26Å; I56-I68 HydrophobicContact CG2-CD1 4.08Å; I56-I68 WeakPolarHBondContact O-CB 3.42Å; I56-I68 PolarHBondContact O-N 3.03Å
69A98.3Very high94.7Very high29 Ų2958.8 Ų58.824%0.2428%0.279CS..EExtended strand (participates in β ladder)trans-159.7161.3-17500000112.6R55 I56R55-A69 WeakPolarHBondContact CA-O 3.36Å; I56-A69 HydrophobicContact CD1-CB 4.25Å; I56-A69 HydrophobicContact CG1-CB 4.47Å; I56-A69 PolarHBondContact N-O 3.29Å
70S98.4Very high94.9Very high25 Ų2558.7 Ų58.718%0.17528%0.279CS..EExtended strand (participates in β ladder)trans-112.7134.4169.1-700000109.9Y67Y67-S70 PolarHBondContact OH-N 3.38Å; Y67-S70 PolarHBondContact OH-OG 2.9Å
71M98.7Very high95.2Very high1 Ų153 Ų531%0.00526%0.256CS..EExtended strand (participates in β ladder)trans-109.499178.6-62.2167.761.200107.8F46 I54 I56 L90 W102F46-M71 HydrophobicContact CD1-SD 4.35Å; F46-M71 HydrophobicContact CE1-SD 4.28Å; I54-M71 HydrophobicContact CB-CB 4.06Å; I54-M71 HydrophobicContact CB-SD 4.49Å; I54-M71 HydrophobicContact CG2-SD 3.95Å; I54-M71 PolarHBondContact N-O 3.33Å; I54-M71 PolarHBondContact O-N 2.94Å; I56-M71 HydrophobicContact CD1-CG 4.34Å; I56-M71 HydrophobicContact CD1-SD 3.87Å; I56-M71 HydrophobicContact CG1-CG 4.44Å; I56-M71 HydrophobicContact CG1-SD 3.94Å; M71-L90 HydrophobicContact CE-CD2 4.31Å; M71-W102 HydrophobicContact CB-CE3 3.99Å; M71-W102 HydrophobicContact CB-CH2 4.43Å; M71-W102 HydrophobicContact CB-CZ3 3.79Å; M71-W102 HydrophobicContact CE-CB 3.4Å; M71-W102 VanDerWaalsContact CE-CB 3.4Å; M71-W102 HydrophobicContact CE-CD2 3.53Å; M71-W102 HydrophobicContact CE-CE3 3.48Å; M71-W102 VanDerWaalsContact CE-CE3 3.48Å; M71-W102 HydrophobicContact CE-CG 3.51Å; M71-W102 HydrophobicContact CE-CZ3 4.38Å
72E98.4Very high96.1Very high52 Ų5248 Ų4824%0.24323%0.234CC..EExtended strand (participates in β ladder)trans-111.3117.5-168.8-57.3-165.6-170.300112R22 I53 R532R22-E72 IonicContact CZ-OE1 2.85Å; R22-E72 IonicContact CZ-OE2 3.19Å; R22-E72 VanDerWaalsContact NH1-CD 3.32Å; R22-E72 IonicContact NH1-OE1 3.59Å; R22-E72 PolarHBondContact NH1-OE1 3.1Å; R22-E72 IonicContact NH1-OE2 3.55Å; R22-E72 PolarHBondContact NH1-OE2 2.7Å; R22-E72 IonicContact NH2-OE1 2.64Å; R22-E72 PolarHBondContact NH2-OE1 3.1Å; R22-E72 IonicContact NH2-OE2 2.76Å; R22-E72 PolarHBondContact NH2-OE2 2.92Å; I53-E72 HydrophobicContact CD1-CG 4.38Å; I53-E72 HydrophobicContact CG1-CG 4.1Å; I53-E72 HydrophobicContact CG2-CG 4.03Å; E72-R532 IonicContact OE2-NH2 2.91Å; E72-R532 PolarHBondContact OE2-NH2 2.92Å
73H98.4Very high96.9Very high59 Ų5939.8 Ų39.827%0.27320%0.195SC..  trans-162-33.9171.1-161.2-43000112.2K100 W102 C109 R532H73-K100 HydrophobicContact CB-CD 3.94Å; H73-K100 PolarHBondContact CE1-NZ 2.84Å; H73-K100 WeakPolarHBondContact ND1-CE 3.47Å; H73-K100 PolarHBondContact ND1-NZ 3.03Å; H73-W102 HydrophobicContact CB-CH2 3.45Å; H73-W102 VanDerWaalsContact CB-CH2 3.45Å; H73-W102 HydrophobicContact CB-CZ2 4.25Å; H73-W102 HydrophobicContact CB-CZ3 4.1Å; H73-C109 HydrophobicContact CB-CB 4.22Å; H73-R532 WeakPolarHBondContact O-CD 3.44Å
74H98.6Very high97.5Very high2 Ų234.6 Ų34.61%0.00917%0.173CC..  trans-63.7149.7174-75-59.4000111.3S52 V78 S92 S94 D96 T98 K100 W102S52-H74 WeakPolarHBondContact CB-O 3.45Å; S52-H74 PolarHBondContact OG-O 3.16Å; H74-V78 HydrophobicContact CB-CG2 4.02Å; H74-S92 PolarHBondContact NE2-OG 3.45Å; H74-S94 WeakPolarHBondContact CE1-CB 3.48Å; H74-S94 WeakPolarHBondContact ND1-CB 3.42Å; H74-D96 WeakPolarHBondContact CA-OD2 3.37Å; H74-D96 WeakPolarHBondContact CB-OD2 3.44Å; H74-D96 IonicContact CE1-OD1 3.58Å; H74-D96 IonicContact CE1-OD2 3.84Å; H74-D96 IonicContact CG-OD2 3.71Å; H74-D96 IonicContact ND1-OD1 3.06Å; H74-D96 PolarHBondContact ND1-OD1 3.47Å; H74-D96 IonicContact ND1-OD2 2.76Å; H74-D96 PolarHBondContact ND1-OD2 2.93Å; H74-T98 PolarHBondContact CE1-OG1 2.96Å; H74-T98 PolarHBondContact ND1-OG1 3Å; H74-K100 VanDerWaalsContact CE1-CD 3.42Å; H74-K100 WeakPolarHBondContact CE1-CD 3.32Å; H74-K100 WeakPolarHBondContact ND1-CE 3.47Å; H74-W102 AromaticContact CD2-CZ2 3.91Å
75T98.6Very high98Very high15 Ų1525.8 Ų25.89%0.09213%0.134CC..SBendtrans-114.52-176.554.40000113D96 I521 T529 R532T75-D96 PolarHBondContact N-OD2 3.09Å; T75-D96 VanDerWaalsContact N-OD2 3.16Å; T75-D96 VanDerWaalsContact OG1-CB 3.24Å; T75-D96 WeakPolarHBondContact OG1-CB 3.49Å; T75-I521 HydrophobicContact CG2-CD1 3.79Å; T75-I521 HydrophobicContact CG2-CG1 3.97Å; T75-I521 HydrophobicContact CG2-CG2 3.83Å; T75-T529 HydrophobicContact CG2-CG2 3.79Å; T75-T529 PolarHBondContact OG1-OG1 2.91Å; T75-R532 HydrophobicContact CG2-CB 4.44Å
76D98.7Very high98Very high13 Ų1328.4 Ų28.47%0.0715%0.148CC..SBendtrans-148.3-177.7176.8-145.6-46.7000109.1S52 V78 S94 D96 K429S52-D76 VanDerWaalsContact CA-O 3.28Å; S52-D76 WeakPolarHBondContact CA-O 3.45Å; S52-D76 WeakPolarHBondContact CB-O 3.37Å; D76-V78 PolarHBondContact O-N 3.37Å; D76-S94 PolarHBondContact O-OG 3.07Å; D76-D96 HydrophobicContact CB-CB 4.01Å; D76-K429 WeakPolarHBondContact OD2-CD 3.43Å; D76-K429 WeakPolarHBondContact OD2-CE 3.32Å; D76-K429 IonicContact OD2-NZ 3.47Å; D76-K429 PolarHBondContact OD2-NZ 3.01Å
77W98.9Very high97.9Very high70 Ų7027.7 Ų27.727%0.26514%0.144SC..  trans-51.1126.3-175.4-66.47.9000112.3R50 N79 S94 S95 K429R50-W77 HydrophobicContact CB-CD2 4.16Å; R50-W77 HydrophobicContact CB-CG 3.99Å; R50-W77 HydrophobicContact CG-CD2 3.82Å; R50-W77 HydrophobicContact CG-CE3 4.18Å; R50-W77 HydrophobicContact CG-CG 3.98Å; R50-W77 PolarHBondContact O-NE1 3Å; W77-N79 PolarHBondContact O-N 3.03Å; W77-S94 CarbonylContact O-C 3.57Å; W77-S94 VanDerWaalsContact O-CA 3.23Å; W77-S94 WeakPolarHBondContact O-CA 3.35Å; W77-S94 PolarHBondContact O-OG 2.96Å; W77-S94 VanDerWaalsContact O-OG 3.11Å; W77-S95 PolarHBondContact O-N 3.43Å; W77-K429 PolarHBondContact NE1-O 2.89Å
78V98.9Very high97.9Very high0 Ų031.1 Ų31.10%016%0.16CC..EExtended strand (participates in β ladder)trans-79.7111.3166.3-169.40000107.2N34 A48 G49 I54 H74 D76 I81 A93N34-V78 VanDerWaalsContact CB-O 3.29Å; N34-V78 WeakPolarHBondContact CB-O 3.46Å; N34-V78 PolarHBondContact ND2-O 2.99Å; A48-V78 HydrophobicContact CB-CB 3.95Å; A48-V78 HydrophobicContact CB-CG1 3.69Å; G49-V78 PolarHBondContact O-N 3.38Å; I54-V78 HydrophobicContact CD1-CG1 4.07Å; I54-V78 HydrophobicContact CG1-CB 4.45Å; I54-V78 HydrophobicContact CG1-CG1 4Å; I54-V78 HydrophobicContact CG1-CG2 4.13Å; H74-V78 HydrophobicContact CB-CG2 4.02Å; D76-V78 PolarHBondContact O-N 3.37Å; V78-I81 HydrophobicContact CG1-CG2 3.97Å; V78-A93 CarbonylContact C-O 3.52Å
79N98.9Very high97.9Very high10 Ų1028.7 Ų28.75%0.05315%0.148CC..EExtended strand (participates in β ladder)trans-86.9-34.6-171.3-69.4-58.1000112.8N34 W77 A93 S95 V120 K121N34-N79 WeakPolarHBondContact CB-O 3.17Å; W77-N79 PolarHBondContact O-N 3.03Å; N79-A93 PolarHBondContact N-O 3.28Å; N79-S95 PolarHBondContact ND2-N 2.82Å; N79-S95 VanDerWaalsContact ND2-N 3.17Å; N79-S95 PolarHBondContact ND2-OG 3.22Å; N79-V120 WeakPolarHBondContact CB-O 3.3Å; N79-V120 PolarHBondContact ND2-O 3.07Å; N79-K121 PolarHBondContact OD1-NZ 3.08Å
80D98.9Very high97.9Very high10 Ų1027.3 Ų27.35%0.05314%0.136CC..EExtended strand (participates in β ladder)trans-152.8154.5179.6-143.47.9000111.1A35 S92 A93 L123 K303A35-D80 WeakPolarHBondContact CB-OD1 3.07Å; D80-S92 WeakPolarHBondContact O-CA 3.21Å; D80-A93 HydrophobicContact CB-CB 4.49Å; D80-A93 PolarHBondContact N-O 3.01Å; D80-A93 PolarHBondContact O-N 3.38Å; D80-L123 HydrophobicContact CB-CB 4.34Å; D80-L123 HydrophobicContact CB-CD1 4.46Å; D80-L123 HydrophobicContact CB-CG 4.22Å; D80-L123 PolarHBondContact OD2-N 3.44Å; D80-K303 IonicContact OD1-NZ 3.82Å; D80-K303 PolarHBondContact OD1-NZ 2.81Å; D80-K303 IonicContact OD2-NZ 2.78Å
81I98.9Very high97.9Very high1 Ų126.1 Ų26.11%0.00513%0.128CC..EExtended strand (participates in β ladder)trans-140.3144.8176.449165.3000110.6A35 Q37 F46 A48 I54 V78 L90 I91A35-I81 HydrophobicContact CB-CG1 3.94Å; Q37-I81 HydrophobicContact CB-CD1 4.19Å; Q37-I81 HydrophobicContact CG-CB 4.43Å; Q37-I81 HydrophobicContact CG-CD1 4.02Å; Q37-I81 HydrophobicContact CG-CG1 3.89Å; Q37-I81 VanDerWaalsContact CG-O 3.28Å; Q37-I81 WeakPolarHBondContact CG-O 3.27Å; F46-I81 HydrophobicContact CB-CD1 3.76Å; A48-I81 HydrophobicContact CB-CB 4.49Å; A48-I81 HydrophobicContact CB-CD1 4.03Å; A48-I81 HydrophobicContact CB-CG1 3.9Å; A48-I81 HydrophobicContact CB-CG2 3.84Å; I54-I81 HydrophobicContact CD1-CG2 3.9Å; I54-I81 HydrophobicContact CG1-CG2 4.32Å; V78-I81 HydrophobicContact CG1-CG2 3.97Å; I81-L90 HydrophobicContact CB-CD1 4.49Å; I81-L90 HydrophobicContact CB-CD2 4.34Å; I81-L90 HydrophobicContact CD1-CD1 4.45Å; I81-L90 HydrophobicContact CG2-CD2 3.96Å; I81-I91 CarbonylContact C-O 3.59Å; I81-I91 VanDerWaalsContact CA-O 3.26Å; I81-I91 WeakPolarHBondContact CA-O 3.5Å
82V98.8Very high97.9Very high9 Ų926.1 Ų26.16%0.05513%0.128CC..EExtended strand (participates in β ladder)trans-126.9129.2174.8166.50000108.5C84 L90 I91 L123 Y125 V132V82-C84 HydrophobicContact CG1-CB 4.41Å; V82-L90 CarbonylContact O-C 3.31Å; V82-L90 WeakPolarHBondContact O-CA 3.43Å; V82-I91 PolarHBondContact N-O 3.11Å; V82-I91 PolarHBondContact O-N 3.03Å; V82-L123 HydrophobicContact CB-CD1 4.41Å; V82-L123 HydrophobicContact CG2-CB 3.59Å; V82-L123 HydrophobicContact CG2-CD1 4.1Å; V82-Y125 HydrophobicContact CG1-CD1 4.01Å; V82-Y125 HydrophobicContact CG1-CD2 3.97Å; V82-Y125 HydrophobicContact CG1-CG 3.6Å; V82-V132 HydrophobicContact CG1-CG2 4.19Å
83L98.6Very high98Very high20 Ų2023.6 Ų23.611%0.10512%0.117CC..EExtended strand (participates in β ladder)trans-96.7122.8170.9-169.272.6000109.4Q37 D39 F46 L90 A104Q37-L83 HydrophobicContact CB-CB 3.99Å; Q37-L83 HydrophobicContact CG-CB 4.22Å; Q37-L83 VanDerWaalsContact OE1-N 3.07Å; D39-L83 HydrophobicContact CB-CD2 3.64Å; F46-L83 HydrophobicContact CD2-CD1 4.3Å; F46-L83 HydrophobicContact CD2-CD2 4.35Å; F46-L83 HydrophobicContact CE2-CD1 3.83Å; F46-L83 HydrophobicContact CE2-CD2 4.01Å; F46-L83 HydrophobicContact CZ-CD1 4.08Å; L83-L90 HydrophobicContact CD1-CB 4.27Å; L83-L90 HydrophobicContact CD1-CD1 4.37Å; L83-A104 HydrophobicContact CD1-CB 3.87Å
84C96.8Very high98Very high2 Ų220.8 Ų20.81%0.01410%0.104CC..EExtended strand (participates in β ladder)trans-132.9175.5-173.553.50000112.1V82 N86 G87 K88 T89 Y125 E130V82-C84 HydrophobicContact CG1-CB 4.41Å; C84-N86 VanDerWaalsContact C-N 3.31Å; C84-N86 PolarHBondContact O-N 2.88Å; C84-G87 PolarHBondContact O-N 3.38Å; C84-K88 PolarHBondContact O-N 2.95Å; C84-T89 PolarHBondContact N-O 3.5Å; C84-T89 PolarHBondContact O-N 2.74Å; C84-T89 PolarHBondContact SG-O 3.09Å; C84-T89 VanDerWaalsContact SG-O 3.4Å; C84-Y125 HydrophobicContact CB-CD2 4.31Å; C84-Y125 HydrophobicContact CB-CE1 4.36Å; C84-Y125 HydrophobicContact CB-CE2 3.54Å; C84-E130 WeakPolarHBondContact CB-OE2 3.25Å
85C95.6Very high98Very high19 Ų1920.8 Ų20.813%0.12810%0.104CC..THydrogen-bonded Turntrans52.744.6-179.5-53.60000113.7G87 K88 E130 V146C85-G87 PolarHBondContact O-N 3.2Å; C85-K88 HydrophobicContact CB-CB 4.36Å; C85-K88 WeakPolarHBondContact O-CB 3.29Å; C85-K88 WeakPolarHBondContact O-CG 3.46Å; C85-K88 PolarHBondContact O-N 3.34Å; C85-E130 WeakPolarHBondContact CA-OE1 3.09Å; C85-E130 PolarHBondContact N-OE1 3.3Å; C85-E130 PolarHBondContact N-OE2 3.27Å; C85-E130 VanDerWaalsContact N-OE2 3.15Å; C85-V146 WeakPolarHBondContact SG-CG1 3.4Å
86N94.1Very high98Very high126 Ų12620.2 Ų20.267%0.67410%0.1SC*.THydrogen-bonded Turntrans55.744.8-177.5-57.7-40.8000113.8C84 K88C84-N86 VanDerWaalsContact C-N 3.31Å; C84-N86 PolarHBondContact O-N 2.88Å; N86-K88 VanDerWaalsContact C-N 3.32Å; N86-K88 PolarHBondContact O-N 3.09Å
87G94.2Very high97.9Very high4 Ų419.9 Ų19.94%0.04110%0.098CC..THydrogen-bonded Turntrans87.8-6.5175.300000114.9C84 C85 A104 H105C84-G87 PolarHBondContact O-N 3.38Å; C85-G87 PolarHBondContact O-N 3.2Å; G87-A104 WeakPolarHBondContact O-CB 3.39Å; G87-H105 PolarHBondContact O-CD2 2.8Å; G87-H105 PolarHBondContact O-NE2 3.25Å
88K96.6Very high97.9Very high125 Ų12516.7 Ų16.754%0.5439%0.087SC..THydrogen-bonded Turntrans-74.3-34.9-177.5-65.6177.7-177.6177.80113.3C84 C85 N86 A104C84-K88 PolarHBondContact O-N 2.95Å; C85-K88 HydrophobicContact CB-CB 4.36Å; C85-K88 WeakPolarHBondContact O-CB 3.29Å; C85-K88 WeakPolarHBondContact O-CG 3.46Å; C85-K88 PolarHBondContact O-N 3.34Å; N86-K88 VanDerWaalsContact C-N 3.32Å; N86-K88 PolarHBondContact O-N 3.09Å; K88-A104 PolarHBondContact O-N 3.49Å
89T98.2Very high97.9Very high10 Ų1016.7 Ų16.76%0.0619%0.087CC..EExtended strand (participates in β ladder)trans-121.6138.3-171.6-54.60000109.6C84 I91 V101 W102 V146 T150C84-T89 PolarHBondContact N-O 3.5Å; C84-T89 PolarHBondContact O-N 2.74Å; C84-T89 PolarHBondContact SG-O 3.09Å; C84-T89 VanDerWaalsContact SG-O 3.4Å; T89-I91 HydrophobicContact CG2-CD1 4.22Å; T89-V101 HydrophobicContact CG2-CG1 4.09Å; T89-W102 WeakPolarHBondContact CA-O 3.48Å; T89-V146 HydrophobicContact CG2-CG1 3.98Å; T89-T150 HydrophobicContact CG2-CG2 3.84Å
90L98.8Very high97.9Very high0 Ų016.5 Ų16.50%09%0.085CC..EExtended strand (participates in β ladder)trans-120.8138.8170.1-177.1146.4000108.9F46 I54 M71 I81 V82 L83 W102 A104F46-L90 HydrophobicContact CB-CD1 4.05Å; F46-L90 HydrophobicContact CD1-CD1 3.53Å; F46-L90 HydrophobicContact CE1-CD1 4.06Å; F46-L90 HydrophobicContact CG-CD1 3.79Å; I54-L90 HydrophobicContact CD1-CD2 3.92Å; M71-L90 HydrophobicContact CE-CD2 4.31Å; I81-L90 HydrophobicContact CB-CD1 4.49Å; I81-L90 HydrophobicContact CB-CD2 4.34Å; I81-L90 HydrophobicContact CD1-CD1 4.45Å; I81-L90 HydrophobicContact CG2-CD2 3.96Å; V82-L90 CarbonylContact O-C 3.31Å; V82-L90 WeakPolarHBondContact O-CA 3.43Å; L83-L90 HydrophobicContact CD1-CB 4.27Å; L83-L90 HydrophobicContact CD1-CD1 4.37Å; L90-W102 HydrophobicContact CB-CB 4.23Å; L90-W102 HydrophobicContact CD2-CB 4.47Å; L90-W102 HydrophobicContact CD2-CG 4.1Å; L90-W102 PolarHBondContact N-O 2.9Å; L90-W102 VanDerWaalsContact O-CD1 3.26Å; L90-W102 PolarHBondContact O-N 3.25Å; L90-A104 HydrophobicContact CB-CB 3.88Å
91I98.8Very high97.9Very high1 Ų116 Ų161%0.0058%0.083CC..EExtended strand (participates in β ladder)trans-113135.1171.5-53.4-62.9000107.8I81 V82 T89 V99 K100 V101 L123 V132 L149I81-I91 CarbonylContact C-O 3.59Å; I81-I91 VanDerWaalsContact CA-O 3.26Å; I81-I91 WeakPolarHBondContact CA-O 3.5Å; V82-I91 PolarHBondContact N-O 3.11Å; V82-I91 PolarHBondContact O-N 3.03Å; T89-I91 HydrophobicContact CG2-CD1 4.22Å; I91-V99 HydrophobicContact CG2-CG1 3.57Å; I91-K100 WeakPolarHBondContact CA-O 3.29Å; I91-V101 HydrophobicContact CD1-CB 4.1Å; I91-V101 HydrophobicContact CD1-CG1 3.82Å; I91-V101 HydrophobicContact CD1-CG2 3.85Å; I91-L123 HydrophobicContact CB-CD1 4.35Å; I91-L123 HydrophobicContact CG2-CD1 4.02Å; I91-L123 HydrophobicContact CG2-CD2 4.29Å; I91-L123 WeakPolarHBondContact O-CD1 3.34Å; I91-V132 HydrophobicContact CG1-CG2 4.27Å; I91-V132 HydrophobicContact CG2-CG1 4.16Å; I91-L149 HydrophobicContact CD1-CD1 4.27Å
92S98.9Very high97.8Very high0 Ų016 Ų160%08%0.083CC..EExtended strand (participates in β ladder)trans-126.9148.1178.364.50000112.2H74 D80 V99 K100 W102H74-S92 PolarHBondContact NE2-OG 3.45Å; D80-S92 WeakPolarHBondContact O-CA 3.21Å; S92-V99 CarbonylContact O-C 3.49Å; S92-V99 WeakPolarHBondContact O-CA 3.06Å; S92-V99 WeakPolarHBondContact O-CG1 3.46Å; S92-K100 PolarHBondContact N-O 3.01Å; S92-K100 PolarHBondContact O-N 2.56Å; S92-W102 PolarHBondContact OG-NE1 3.3Å
93A98.9Very high97.8Very high0 Ų017.5 Ų17.50%09%0.09CC..EExtended strand (participates in β ladder)trans-120.4134.6176.600000109.9V78 N79 D80 V120 L123V78-A93 CarbonylContact C-O 3.52Å; N79-A93 PolarHBondContact N-O 3.28Å; D80-A93 HydrophobicContact CB-CB 4.49Å; D80-A93 PolarHBondContact N-O 3.01Å; D80-A93 PolarHBondContact O-N 3.38Å; A93-V120 HydrophobicContact CB-CB 3.83Å; A93-V120 HydrophobicContact CB-CG1 3.51Å; A93-L123 HydrophobicContact CB-CD1 4.06Å; A93-L123 HydrophobicContact CB-CD2 3.95Å; A93-L123 HydrophobicContact CB-CG 3.75Å
94S98.9Very high97.8Very high0 Ų016.5 Ų16.50%09%0.085CC..EExtended strand (participates in β ladder)trans-133.5157.2-172.9175.80000114.2H74 D76 W77 D96 T97 T98 V120H74-S94 WeakPolarHBondContact CE1-CB 3.48Å; H74-S94 WeakPolarHBondContact ND1-CB 3.42Å; D76-S94 PolarHBondContact O-OG 3.07Å; W77-S94 CarbonylContact O-C 3.57Å; W77-S94 VanDerWaalsContact O-CA 3.23Å; W77-S94 WeakPolarHBondContact O-CA 3.35Å; W77-S94 PolarHBondContact O-OG 2.96Å; W77-S94 VanDerWaalsContact O-OG 3.11Å; S94-D96 VanDerWaalsContact CB-OD1 3.28Å; S94-D96 WeakPolarHBondContact CB-OD1 3.43Å; S94-D96 PolarHBondContact O-N 2.83Å; S94-D96 PolarHBondContact OG-N 3.1Å; S94-D96 PolarHBondContact OG-OD1 3Å; S94-D96 PolarHBondContact OG-OD2 3.27Å; S94-T97 PolarHBondContact O-N 3.24Å; S94-T98 PolarHBondContact N-O 3.14Å; S94-T98 VanDerWaalsContact N-O 3.15Å; S94-V120 PolarHBondContact O-N 3.01Å
95S98.7Very high97.7Very high2 Ų220.4 Ų20.41%0.01410%0.103CC..THydrogen-bonded Turntrans-67.2-11167.7-63.50000112.7W77 N79 T97 Y119W77-S95 PolarHBondContact O-N 3.43Å; N79-S95 PolarHBondContact ND2-N 2.82Å; N79-S95 VanDerWaalsContact ND2-N 3.17Å; N79-S95 PolarHBondContact ND2-OG 3.22Å; S95-T97 PolarHBondContact O-N 3.1Å; S95-T97 VanDerWaalsContact O-N 3.08Å; S95-Y119 WeakPolarHBondContact O-CD1 3.34Å; S95-Y119 WeakPolarHBondContact O-CE1 3.11Å
96D97.8Very high97.6Very high2 Ų227.5 Ų27.51%0.01113%0.132CC..THydrogen-bonded Turntrans-74.710.4170.468.620.1000113.9H74 T75 D76 S94 T98H74-D96 WeakPolarHBondContact CA-OD2 3.37Å; H74-D96 WeakPolarHBondContact CB-OD2 3.44Å; H74-D96 IonicContact CE1-OD1 3.58Å; H74-D96 IonicContact CE1-OD2 3.84Å; H74-D96 IonicContact CG-OD2 3.71Å; H74-D96 IonicContact ND1-OD1 3.06Å; H74-D96 PolarHBondContact ND1-OD1 3.47Å; H74-D96 IonicContact ND1-OD2 2.76Å; H74-D96 PolarHBondContact ND1-OD2 2.93Å; T75-D96 PolarHBondContact N-OD2 3.09Å; T75-D96 VanDerWaalsContact N-OD2 3.16Å; T75-D96 VanDerWaalsContact OG1-CB 3.24Å; T75-D96 WeakPolarHBondContact OG1-CB 3.49Å; D76-D96 HydrophobicContact CB-CB 4.01Å; S94-D96 VanDerWaalsContact CB-OD1 3.28Å; S94-D96 WeakPolarHBondContact CB-OD1 3.43Å; S94-D96 PolarHBondContact O-N 2.83Å; S94-D96 PolarHBondContact OG-N 3.1Å; S94-D96 PolarHBondContact OG-OD1 3Å; S94-D96 PolarHBondContact OG-OD2 3.27Å; D96-T98 PolarHBondContact O-N 3.29Å; D96-T98 VanDerWaalsContact OD1-CB 3.31Å; D96-T98 WeakPolarHBondContact OD1-CB 3.35Å; D96-T98 PolarHBondContact OD1-N 2.89Å; D96-T98 PolarHBondContact OD1-OG1 3.14Å
97T98.1Very high97.7Very high6 Ų622.2 Ų22.24%0.03711%0.107CC..SBendtrans72.35.2-179.373.90000115.1S94 S95S94-T97 PolarHBondContact O-N 3.24Å; S95-T97 PolarHBondContact O-N 3.1Å; S95-T97 VanDerWaalsContact O-N 3.08Å
98T98.3Very high97.8Very high3 Ų326.7 Ų26.72%0.01813%0.125CC..  trans-106.6152.6-177.374.10000113.7H74 S94 D96 T112 R114H74-T98 PolarHBondContact CE1-OG1 2.96Å; H74-T98 PolarHBondContact ND1-OG1 3Å; S94-T98 PolarHBondContact N-O 3.14Å; S94-T98 VanDerWaalsContact N-O 3.15Å; D96-T98 PolarHBondContact O-N 3.29Å; D96-T98 VanDerWaalsContact OD1-CB 3.31Å; D96-T98 WeakPolarHBondContact OD1-CB 3.35Å; D96-T98 PolarHBondContact OD1-N 2.89Å; D96-T98 PolarHBondContact OD1-OG1 3.14Å; T98-T112 HydrophobicContact CG2-CG2 3.78Å; T98-R114 HydrophobicContact CG2-CG 4.27Å
99V98.8Very high97.9Very high0 Ų022.1 Ų22.10%011%0.108CC..EExtended strand (participates in β ladder)trans-107.1132.1160.9175.40000107.7I91 S92 L113 V120I91-V99 HydrophobicContact CG2-CG1 3.57Å; S92-V99 CarbonylContact O-C 3.49Å; S92-V99 WeakPolarHBondContact O-CA 3.06Å; S92-V99 WeakPolarHBondContact O-CG1 3.46Å; V99-L113 HydrophobicContact CB-CB 4.18Å; V99-L113 HydrophobicContact CB-CD1 4.32Å; V99-L113 HydrophobicContact CG1-CD1 4.07Å; V99-L113 PolarHBondContact N-O 3.04Å; V99-L113 VanDerWaalsContact N-O 3.07Å; V99-L113 PolarHBondContact O-N 3.33Å; V99-V120 HydrophobicContact CG2-CB 4.49Å; V99-V120 HydrophobicContact CG2-CG1 3.9Å; V99-V120 HydrophobicContact CG2-CG2 4.22Å
100K98.6Very high97.8Very high6 Ų625 Ų253%0.02612%0.122CC..EExtended strand (participates in β ladder)trans-118145.4179.9-70.3179.3-174.5-72.30111.8H73 H74 I91 S92 W102 S111 T112H73-K100 HydrophobicContact CB-CD 3.94Å; H73-K100 PolarHBondContact CE1-NZ 2.84Å; H73-K100 WeakPolarHBondContact ND1-CE 3.47Å; H73-K100 PolarHBondContact ND1-NZ 3.03Å; H74-K100 VanDerWaalsContact CE1-CD 3.42Å; H74-K100 WeakPolarHBondContact CE1-CD 3.32Å; H74-K100 WeakPolarHBondContact ND1-CE 3.47Å; I91-K100 WeakPolarHBondContact CA-O 3.29Å; S92-K100 PolarHBondContact N-O 3.01Å; S92-K100 PolarHBondContact O-N 2.56Å; K100-W102 HydrophobicContact CB-CZ2 3.88Å; K100-W102 VanDerWaalsContact CB-NE1 3.34Å; K100-W102 HydrophobicContact CD-CH2 4.25Å; K100-W102 HydrophobicContact CD-CZ2 3.64Å; K100-W102 HydrophobicContact CG-CZ2 4.42Å; K100-W102 PolarHBondContact O-NE1 3.15Å; K100-S111 WeakPolarHBondContact CA-O 3.47Å; K100-T112 HydrophobicContact CG-CG2 4.24Å; K100-T112 PolarHBondContact NZ-OG1 3.2Å
101V98.6Very high97.6Very high0 Ų026 Ų260%013%0.13CC..EExtended strand (participates in β ladder)trans-107.8130.8177.3-172.70000107.9T89 I91 M110 S111 L113 L149T89-V101 HydrophobicContact CG2-CG1 4.09Å; I91-V101 HydrophobicContact CD1-CB 4.1Å; I91-V101 HydrophobicContact CD1-CG1 3.82Å; I91-V101 HydrophobicContact CD1-CG2 3.85Å; V101-M110 PolarHBondContact O-N 3.46Å; V101-S111 PolarHBondContact N-O 3.18Å; V101-S111 PolarHBondContact O-N 2.88Å; V101-L113 HydrophobicContact CG2-CD1 4.49Å; V101-L149 HydrophobicContact CG2-CB 4.2Å; V101-L149 HydrophobicContact CG2-CD1 3.93Å; V101-L149 HydrophobicContact CG2-CG 4.5Å
102W98.8Very high97.5Very high2 Ų228 Ų281%0.00814%0.142CC..EExtended strand (participates in β ladder)trans-129.1145.7-172.6-51.680000111.5I54 M71 H73 H74 T89 L90 S92 K100 A104 F108 C109I54-W102 HydrophobicContact CD1-CZ2 4.1Å; M71-W102 HydrophobicContact CB-CE3 3.99Å; M71-W102 HydrophobicContact CB-CH2 4.43Å; M71-W102 HydrophobicContact CB-CZ3 3.79Å; M71-W102 HydrophobicContact CE-CB 3.4Å; M71-W102 VanDerWaalsContact CE-CB 3.4Å; M71-W102 HydrophobicContact CE-CD2 3.53Å; M71-W102 HydrophobicContact CE-CE3 3.48Å; M71-W102 VanDerWaalsContact CE-CE3 3.48Å; M71-W102 HydrophobicContact CE-CG 3.51Å; M71-W102 HydrophobicContact CE-CZ3 4.38Å; H73-W102 HydrophobicContact CB-CH2 3.45Å; H73-W102 VanDerWaalsContact CB-CH2 3.45Å; H73-W102 HydrophobicContact CB-CZ2 4.25Å; H73-W102 HydrophobicContact CB-CZ3 4.1Å; H74-W102 AromaticContact CD2-CZ2 3.91Å; T89-W102 WeakPolarHBondContact CA-O 3.48Å; L90-W102 HydrophobicContact CB-CB 4.23Å; L90-W102 HydrophobicContact CD2-CB 4.47Å; L90-W102 HydrophobicContact CD2-CG 4.1Å; L90-W102 PolarHBondContact N-O 2.9Å; L90-W102 VanDerWaalsContact O-CD1 3.26Å; L90-W102 PolarHBondContact O-N 3.25Å; S92-W102 PolarHBondContact OG-NE1 3.3Å; K100-W102 HydrophobicContact CB-CZ2 3.88Å; K100-W102 VanDerWaalsContact CB-NE1 3.34Å; K100-W102 HydrophobicContact CD-CH2 4.25Å; K100-W102 HydrophobicContact CD-CZ2 3.64Å; K100-W102 HydrophobicContact CG-CZ2 4.42Å; K100-W102 PolarHBondContact O-NE1 3.15Å; W102-A104 PolarHBondContact O-N 3.46Å; W102-F108 WeakPolarHBondContact CA-O 3.4Å; W102-C109 HydrophobicContact CD2-CB 4.14Å; W102-C109 VanDerWaalsContact CE3-CA 3.47Å; W102-C109 HydrophobicContact CE3-CB 3.62Å; W102-C109 VanDerWaalsContact CE3-N 3.34Å; W102-C109 HydrophobicContact CH2-CB 4.05Å; W102-C109 HydrophobicContact CZ3-CB 3.57Å
103N98.3Very high97.4Very high39 Ų3928.5 Ų28.521%0.20914%0.144CC..EExtended strand (participates in β ladder)trans-79.7106.8159.5-170.9-59.2000108.2H105 K106 G107 F108 M110N103-H105 VanDerWaalsContact C-N 3.34Å; N103-H105 PolarHBondContact O-N 3.15Å; N103-H105 PolarHBondContact OD1-N 3.19Å; N103-K106 HydrophobicContact CB-CB 4.43Å; N103-K106 WeakPolarHBondContact OD1-CB 3.45Å; N103-K106 PolarHBondContact OD1-N 3.29Å; N103-G107 WeakPolarHBondContact O-CA 3.48Å; N103-G107 PolarHBondContact O-N 3.23Å; N103-F108 HydrophobicContact CB-CD1 4.08Å; N103-F108 HydrophobicContact CB-CE1 3.68Å; N103-F108 HydrophobicContact CB-CE2 4.49Å; N103-F108 HydrophobicContact CB-CZ 3.9Å; N103-F108 PolarHBondContact N-O 2.9Å; N103-F108 PolarHBondContact O-N 2.83Å; N103-M110 HydrophobicContact CB-CG 4.32Å; N103-M110 HydrophobicContact CB-SD 3.96Å
104A97.6Very high97.2Very high0 Ų033.5 Ų33.50%016%0.163CC..THydrogen-bonded Turntrans-75.4-23-173.300000113.2F46 L83 G87 K88 L90 W102F46-A104 HydrophobicContact CE1-CB 4.12Å; F46-A104 HydrophobicContact CZ-CB 4Å; L83-A104 HydrophobicContact CD1-CB 3.87Å; G87-A104 WeakPolarHBondContact O-CB 3.39Å; K88-A104 PolarHBondContact O-N 3.49Å; L90-A104 HydrophobicContact CB-CB 3.88Å; W102-A104 PolarHBondContact O-N 3.46Å
105H95Very high97Very high84 Ų8435.4 Ų35.439%0.38918%0.175SC..THydrogen-bonded Turntrans-76-42176.3-71.9-173.6000112.4G87 N103G87-H105 PolarHBondContact O-CD2 2.8Å; G87-H105 PolarHBondContact O-NE2 3.25Å; N103-H105 VanDerWaalsContact C-N 3.34Å; N103-H105 PolarHBondContact O-N 3.15Å; N103-H105 PolarHBondContact OD1-N 3.19Å
106K94.9Very high96.9Very high168 Ų16835.3 Ų35.373%0.7317%0.174SC*.THydrogen-bonded Turntrans-93.3-18.2-177.7-67.5-177.8171.5-174.10113.6N103 F108N103-K106 HydrophobicContact CB-CB 4.43Å; N103-K106 WeakPolarHBondContact OD1-CB 3.45Å; N103-K106 PolarHBondContact OD1-N 3.29Å; K106-F108 HydrophobicContact CB-CD1 3.64Å; K106-F108 HydrophobicContact CB-CE1 3.63Å; K106-F108 HydrophobicContact CD-CE1 3.76Å; K106-F108 HydrophobicContact CG-CE1 4.33Å
107G95.8Very high96.8Very high14 Ų1443.2 Ų43.214%0.14421%0.208CC..THydrogen-bonded Turntrans78.932.7172.600000115.7N103N103-G107 WeakPolarHBondContact O-CA 3.48Å; N103-G107 PolarHBondContact O-N 3.23Å
108F96.3Very high96.8Very high98 Ų9845.9 Ų45.943%0.4322%0.223SC..EExtended strand (participates in β ladder)trans-128.6154.2177.772.6-89.5000113W102 N103 K106 M110W102-F108 WeakPolarHBondContact CA-O 3.4Å; N103-F108 HydrophobicContact CB-CD1 4.08Å; N103-F108 HydrophobicContact CB-CE1 3.68Å; N103-F108 HydrophobicContact CB-CE2 4.49Å; N103-F108 HydrophobicContact CB-CZ 3.9Å; N103-F108 PolarHBondContact N-O 2.9Å; N103-F108 PolarHBondContact O-N 2.83Å; K106-F108 HydrophobicContact CB-CD1 3.64Å; K106-F108 HydrophobicContact CB-CE1 3.63Å; K106-F108 HydrophobicContact CD-CE1 3.76Å; K106-F108 HydrophobicContact CG-CE1 4.33Å; F108-M110 HydrophobicContact CD2-CG 4.32Å; F108-M110 HydrophobicContact CE2-CG 3.73Å; F108-M110 HydrophobicContact CZ-CG 4.3Å
109C97.8Very high96.8Very high29 Ų2949.9 Ų49.920%0.19624%0.238CC..EExtended strand (participates in β ladder)trans-79.2127.3178.3-178.20000110.1H73 W102H73-C109 HydrophobicContact CB-CB 4.22Å; W102-C109 HydrophobicContact CD2-CB 4.14Å; W102-C109 VanDerWaalsContact CE3-CA 3.47Å; W102-C109 HydrophobicContact CE3-CB 3.62Å; W102-C109 VanDerWaalsContact CE3-N 3.34Å; W102-C109 HydrophobicContact CH2-CB 4.05Å; W102-C109 HydrophobicContact CZ3-CB 3.57Å
110M96.3Very high96.8Very high70 Ų7049.9 Ų49.935%0.34524%0.238SC..EExtended strand (participates in β ladder)trans-94.7-37.5178.3-64174.360.400112.4V101 N103 F108V101-M110 PolarHBondContact O-N 3.46Å; N103-M110 HydrophobicContact CB-CG 4.32Å; N103-M110 HydrophobicContact CB-SD 3.96Å; F108-M110 HydrophobicContact CD2-CG 4.32Å; F108-M110 HydrophobicContact CE2-CG 3.73Å; F108-M110 HydrophobicContact CZ-CG 4.3Å
111S94.8Very high96.8Very high23 Ų2351.8 Ų51.816%0.16125%0.246CC..EExtended strand (participates in β ladder)trans-154.3152.4-174.2-65.50000112.1K100 V101K100-S111 WeakPolarHBondContact CA-O 3.47Å; V101-S111 PolarHBondContact N-O 3.18Å; V101-S111 PolarHBondContact O-N 2.88Å
112T96Very high96.8Very high42 Ų4251.9 Ų51.926%0.25825%0.247SC..EExtended strand (participates in β ladder)trans-124.2116.1176.9-58.30000110.2T98 K100 R114T98-T112 HydrophobicContact CG2-CG2 3.78Å; K100-T112 HydrophobicContact CG-CG2 4.24Å; K100-T112 PolarHBondContact NZ-OG1 3.2Å; T112-R114 HydrophobicContact CG2-CG 3.92Å
113L96.5Very high96.8Very high10 Ų1052.1 Ų52.15%0.05225%0.249CC..EExtended strand (participates in β ladder)trans-91.9123176.6-48.4175.7000108.9V99 V101 W144 L149 V159V99-L113 HydrophobicContact CB-CB 4.18Å; V99-L113 HydrophobicContact CB-CD1 4.32Å; V99-L113 HydrophobicContact CG1-CD1 4.07Å; V99-L113 PolarHBondContact N-O 3.04Å; V99-L113 VanDerWaalsContact N-O 3.07Å; V99-L113 PolarHBondContact O-N 3.33Å; V101-L113 HydrophobicContact CG2-CD1 4.49Å; L113-W144 HydrophobicContact CB-CH2 4.21Å; L113-W144 HydrophobicContact CB-CZ2 4.45Å; L113-W144 HydrophobicContact CD1-CD2 3.86Å; L113-W144 HydrophobicContact CD1-CE3 3.85Å; L113-W144 HydrophobicContact CD1-CG 4.47Å; L113-W144 HydrophobicContact CD1-CH2 4.02Å; L113-W144 HydrophobicContact CD1-CZ2 4.06Å; L113-W144 HydrophobicContact CD1-CZ3 3.94Å; L113-W144 HydrophobicContact CD2-CZ3 4.4Å; L113-L149 HydrophobicContact CD1-CD1 3.99Å; L113-L149 HydrophobicContact CD1-CD2 3.87Å; L113-L149 HydrophobicContact CD2-CD2 3.86Å; L113-L149 HydrophobicContact CG-CD2 4.46Å; L113-V159 HydrophobicContact CD2-CG1 4.28Å
114R95.1Very high96.8Very high105 Ų10550.5 Ų50.540%0.39624%0.241SC..  trans-117.934.5-170.9-59.1179.5169.8161.5-9.1113.3T98 T112 R528 L530T98-R114 HydrophobicContact CG2-CG 4.27Å; T112-R114 HydrophobicContact CG2-CG 3.92Å; R114-R528 PolarHBondContact O-NH1 3.46Å; R114-L530 PolarHBondContact NH2-O 2.91Å
115T95.2Very high96.8Very high40 Ų4052.8 Ų52.825%0.24525%0.249CC..  trans-84.2-31.4-176.252.40000113.4W144 T161T115-W144 HydrophobicContact CG2-CH2 3.74Å; T115-W144 HydrophobicContact CG2-CZ2 4.49Å; T115-W144 WeakPolarHBondContact OG1-CH2 3.46Å; T115-W144 WeakPolarHBondContact OG1-CZ2 3.36Å; T115-T161 HydrophobicContact CG2-CG2 3.7Å
116H96.6Very high96.9Very high1 Ų148.8 Ų48.81%0.00523%0.231CC..  trans-69.5148.5174.3-75.4-76.9000111.4V120 S134 D138 F142H116-V120 HydrophobicContact CB-CG2 3.65Å; H116-S134 PolarHBondContact CE1-O 2.83Å; H116-S134 WeakPolarHBondContact NE2-CB 3.03Å; H116-S134 PolarHBondContact NE2-O 2.62Å; H116-S134 PolarHBondContact NE2-OG 3.25Å; H116-D138 VanDerWaalsContact CA-OD2 3.27Å; H116-D138 WeakPolarHBondContact CA-OD2 3.07Å; H116-D138 IonicContact CE1-OD1 2.68Å; H116-D138 IonicContact CG-OD2 3.34Å; H116-D138 IonicContact ND1-OD1 4Å; H116-D138 PolarHBondContact ND1-OD1 3.04Å; H116-D138 IonicContact ND1-OD2 2.76Å; H116-D138 PolarHBondContact ND1-OD2 3.47Å; H116-F142 AromaticContact CD2-CD2 3.95Å; H116-F142 AromaticContact CE1-CD2 3.53Å; H116-F142 AromaticContact CE1-CE2 3.94Å; H116-F142 AromaticContact ND1-CD2 3.94Å; H116-F142 AromaticContact ND1-CE2 3.89Å; H116-F142 AromaticContact NE2-CD2 3.54Å
117K95.4Very high96.9Very high167 Ų16746 Ų4673%0.72622%0.219SC*.SBendtrans-111.5-2.2-175.4-63.5178.9179.9174.80113.9D138K117-D138 HydrophobicContact CB-CB 4.23Å; K117-D138 PolarHBondContact N-OD2 2.74Å; K117-D138 VanDerWaalsContact N-OD2 3.1Å
118D97.4Very high96.9Very high63 Ų6349.2 Ų49.234%0.33723%0.233SC..SBendtrans-154-177.8-179.2-155.2-22.7000107.9V120 L137 D138D118-V120 PolarHBondContact O-N 3.25Å; D118-L137 HydrophobicContact CB-CB 3.98Å; D118-D138 HydrophobicContact CB-CB 3.87Å
119Y98.6Very high96.8Very high87 Ų8750.6 Ų50.634%0.34124%0.238SC..  trans-58.2127-171.4-61.5-2.1000111.4S95 K121 G136 L137S95-Y119 WeakPolarHBondContact O-CD1 3.34Å; S95-Y119 WeakPolarHBondContact O-CE1 3.11Å; Y119-K121 PolarHBondContact O-N 3.3Å; Y119-G136 CarbonylContact O-C 3.6Å; Y119-G136 WeakPolarHBondContact O-CA 3.5Å; Y119-L137 HydrophobicContact CD2-CD1 3.89Å; Y119-L137 HydrophobicContact CG-CD1 4.01Å; Y119-L137 PolarHBondContact O-N 3.23Å
120V98.8Very high96.8Very high0 Ų050.6 Ų50.60%024%0.236CC..EExtended strand (participates in β ladder)trans-84.1117.2175.2-163.60000107.7N79 A93 S94 V99 H116 D118 A135N79-V120 WeakPolarHBondContact CB-O 3.3Å; N79-V120 PolarHBondContact ND2-O 3.07Å; A93-V120 HydrophobicContact CB-CB 3.83Å; A93-V120 HydrophobicContact CB-CG1 3.51Å; S94-V120 PolarHBondContact O-N 3.01Å; V99-V120 HydrophobicContact CG2-CB 4.49Å; V99-V120 HydrophobicContact CG2-CG1 3.9Å; V99-V120 HydrophobicContact CG2-CG2 4.22Å; H116-V120 HydrophobicContact CB-CG2 3.65Å; D118-V120 PolarHBondContact O-N 3.25Å; V120-A135 WeakPolarHBondContact CG1-O 3.04Å
121K98.8Very high96.8Very high45 Ų4548.8 Ų48.820%0.19623%0.227CC..EExtended strand (participates in β ladder)trans-103.6-29.5-166.6-66.1-54.8-56.9175.90114.1N79 Y119 A135 L137 I171N79-K121 PolarHBondContact OD1-NZ 3.08Å; Y119-K121 PolarHBondContact O-N 3.3Å; K121-A135 PolarHBondContact N-O 2.9Å; K121-L137 HydrophobicContact CD-CD2 4.23Å; K121-L137 HydrophobicContact CD-CG 4.26Å; K121-L137 HydrophobicContact CG-CD2 3.75Å; K121-L137 HydrophobicContact CG-CG 3.95Å; K121-I171 WeakPolarHBondContact CB-O 3.37Å
122A98.7Very high97Very high3 Ų347.8 Ų47.83%0.02522%0.22CC..EExtended strand (participates in β ladder)trans-146.1147.5-172.700000111.8A135 L174A122-A135 PolarHBondContact N-O 3.42Å; A122-A135 VanDerWaalsContact N-O 3.1Å; A122-A135 PolarHBondContact O-N 3.35Å; A122-L174 HydrophobicContact CB-CB 3.84Å
123L98.9Very high97.1Very high7 Ų745.8 Ų45.84%0.03721%0.208CC..EExtended strand (participates in β ladder)trans-117.3152.8168.9-66.3173.7000109.7D80 V82 I91 A93 V132 A133D80-L123 HydrophobicContact CB-CB 4.34Å; D80-L123 HydrophobicContact CB-CD1 4.46Å; D80-L123 HydrophobicContact CB-CG 4.22Å; D80-L123 PolarHBondContact OD2-N 3.44Å; V82-L123 HydrophobicContact CB-CD1 4.41Å; V82-L123 HydrophobicContact CG2-CB 3.59Å; V82-L123 HydrophobicContact CG2-CD1 4.1Å; I91-L123 HydrophobicContact CB-CD1 4.35Å; I91-L123 HydrophobicContact CG2-CD1 4.02Å; I91-L123 HydrophobicContact CG2-CD2 4.29Å; I91-L123 WeakPolarHBondContact O-CD1 3.34Å; A93-L123 HydrophobicContact CB-CD1 4.06Å; A93-L123 HydrophobicContact CB-CD2 3.95Å; A93-L123 HydrophobicContact CB-CG 3.75Å; L123-V132 HydrophobicContact CD2-CG1 4.19Å; L123-A133 CarbonylContact C-O 3.38Å; L123-A133 VanDerWaalsContact CA-O 3.25Å; L123-A133 WeakPolarHBondContact CA-O 3.19Å; L123-A133 WeakPolarHBondContact CD2-O 3.46Å
124A98.6Very high97.2Very high5 Ų545.3 Ų45.34%0.04121%0.205CC..EExtended strand (participates in β ladder)trans-134152.4169.500000110.1V132 A133 L174 M176A124-V132 CarbonylContact O-C 3.57Å; A124-V132 VanDerWaalsContact O-CA 3.27Å; A124-V132 WeakPolarHBondContact O-CA 3.4Å; A124-A133 HydrophobicContact CB-CB 4.35Å; A124-A133 PolarHBondContact N-O 3.46Å; A124-A133 PolarHBondContact O-N 3.31Å; A124-L174 HydrophobicContact CB-CB 4.05Å; A124-L174 HydrophobicContact CB-CD2 3.82Å; A124-L174 HydrophobicContact CB-CG 3.69Å; A124-M176 HydrophobicContact CB-CB 3.98Å
125Y98.3Very high97.4Very high47 Ų4740.3 Ų40.318%0.18419%0.186CC..EExtended strand (participates in β ladder)trans-139.2130.2-172178.4-129.8000112.1V82 C84 K127 E130 L131 V132V82-Y125 HydrophobicContact CG1-CD1 4.01Å; V82-Y125 HydrophobicContact CG1-CD2 3.97Å; V82-Y125 HydrophobicContact CG1-CG 3.6Å; C84-Y125 HydrophobicContact CB-CD2 4.31Å; C84-Y125 HydrophobicContact CB-CE1 4.36Å; C84-Y125 HydrophobicContact CB-CE2 3.54Å; Y125-K127 HydrophobicContact CD1-CB 4.43Å; Y125-K127 HydrophobicContact CE1-CB 3.73Å; Y125-K127 HydrophobicContact CE1-CG 4.05Å; Y125-E130 WeakPolarHBondContact CE2-OE2 3.18Å; Y125-E130 PolarHBondContact OH-OE1 3.09Å; Y125-E130 PolarHBondContact OH-OE2 3.43Å; Y125-L131 WeakPolarHBondContact CA-O 3.4Å; Y125-L131 WeakPolarHBondContact CD2-O 3.41Å; Y125-V132 HydrophobicContact CD2-CG2 3.7Å; Y125-V132 HydrophobicContact CE2-CG2 4.39Å
126A97.1Very high97.5Very high0 Ų038.4 Ų38.40%018%0.175CC..EExtended strand (participates in β ladder)trans-108.9104.6166.600000109.9D128 K129 E130 L131 M176 N177 G180A126-D128 PolarHBondContact O-N 2.74Å; A126-K129 PolarHBondContact O-N 2.89Å; A126-E130 PolarHBondContact O-N 3.38Å; A126-L131 HydrophobicContact CB-CB 4.38Å; A126-L131 PolarHBondContact N-O 3.01Å; A126-L131 PolarHBondContact O-N 3.09Å; A126-M176 HydrophobicContact CB-CG 3.97Å; A126-M176 HydrophobicContact CB-SD 3.37Å; A126-M176 WeakPolarHBondContact CB-SD 3.36Å; A126-N177 WeakPolarHBondContact CB-O 3.36Å; A126-G180 VanDerWaalsContact CB-CA 3.41Å
127K94.9Very high97.6Very high111 Ų11139.7 Ų39.748%0.48318%0.182SC..G310 helixtrans-59.4-43.2-175.3-172176.8179.5176.10113.5Y125 K129 E130 Q178Y125-K127 HydrophobicContact CD1-CB 4.43Å; Y125-K127 HydrophobicContact CE1-CB 3.73Å; Y125-K127 HydrophobicContact CE1-CG 4.05Å; K127-K129 PolarHBondContact O-N 3.25Å; K127-K129 VanDerWaalsContact O-N 3.12Å; K127-E130 PolarHBondContact O-N 2.95Å; K127-Q178 HydrophobicContact CB-CG 4Å; K127-Q178 PolarHBondContact N-O 3.46Å
128D94.1Very high97.7Very high81 Ų8133 Ų3343%0.43315%0.154SC..G310 helixtrans-70.6-14.2-172.8-61.3-9.4000112.9A126 Q178A126-D128 PolarHBondContact O-N 2.74Å; D128-Q178 WeakPolarHBondContact CB-O 3.19Å; D128-Q178 PolarHBondContact N-O 2.99Å; D128-Q178 VanDerWaalsContact N-O 3.1Å; D128-Q178 WeakPolarHBondContact OD1-CG 3.36Å; D128-Q178 PolarHBondContact OD1-NE2 3.29Å
129K94.8Very high97.7Very high126 Ų12636 Ų3655%0.54816%0.16SC..G310 helixtrans-115.9-3.8178.6-63.4-59.9-178.7-169.50113.6A126 K127 L131A126-K129 PolarHBondContact O-N 2.89Å; K127-K129 PolarHBondContact O-N 3.25Å; K127-K129 VanDerWaalsContact O-N 3.12Å; K129-L131 HydrophobicContact CB-CB 4.09Å; K129-L131 PolarHBondContact O-N 2.72Å
130E97.1Very high97.7Very high30 Ų3034.6 Ų34.614%0.1416%0.157CC..THydrogen-bonded Turntrans47.143.7-169.1-63.7-67.4177.400111.8C84 C85 Y125 A126 K127 V146C84-E130 WeakPolarHBondContact CB-OE2 3.25Å; C85-E130 WeakPolarHBondContact CA-OE1 3.09Å; C85-E130 PolarHBondContact N-OE1 3.3Å; C85-E130 PolarHBondContact N-OE2 3.27Å; C85-E130 VanDerWaalsContact N-OE2 3.15Å; Y125-E130 WeakPolarHBondContact CE2-OE2 3.18Å; Y125-E130 PolarHBondContact OH-OE1 3.09Å; Y125-E130 PolarHBondContact OH-OE2 3.43Å; A126-E130 PolarHBondContact O-N 3.38Å; K127-E130 PolarHBondContact O-N 2.95Å; E130-V146 HydrophobicContact CB-CB 4.35Å; E130-V146 WeakPolarHBondContact O-CB 3.35Å; E130-V146 VanDerWaalsContact O-CG2 3.24Å; E130-V146 WeakPolarHBondContact O-CG2 3.24Å; E130-V146 PolarHBondContact O-N 2.91Å
131L97.2Very high97.7Very high32 Ų3234.6 Ų34.617%0.16816%0.157CC..EExtended strand (participates in β ladder)trans-105.9128.2-177.9-176.372.5000109.6Y125 A126 K129 W144 M176 P197Y125-L131 WeakPolarHBondContact CA-O 3.4Å; Y125-L131 WeakPolarHBondContact CD2-O 3.41Å; A126-L131 HydrophobicContact CB-CB 4.38Å; A126-L131 PolarHBondContact N-O 3.01Å; A126-L131 PolarHBondContact O-N 3.09Å; K129-L131 HydrophobicContact CB-CB 4.09Å; K129-L131 PolarHBondContact O-N 2.72Å; L131-W144 WeakPolarHBondContact CD1-O 3.35Å; L131-M176 HydrophobicContact CD2-CE 4.08Å; L131-M176 HydrophobicContact CD2-SD 3.87Å; L131-M176 HydrophobicContact CG-CE 4.35Å; L131-M176 HydrophobicContact CG-SD 4.33Å; L131-P197 HydrophobicContact CD2-CB 4.18Å
132V98.3Very high97.6Very high1 Ų133 Ų331%0.00615%0.15CC..EExtended strand (participates in β ladder)trans-114.5144.6175.91720000109.9V82 I91 L123 A124 Y125 W144 V146V82-V132 HydrophobicContact CG1-CG2 4.19Å; I91-V132 HydrophobicContact CG1-CG2 4.27Å; I91-V132 HydrophobicContact CG2-CG1 4.16Å; L123-V132 HydrophobicContact CD2-CG1 4.19Å; A124-V132 CarbonylContact O-C 3.57Å; A124-V132 VanDerWaalsContact O-CA 3.27Å; A124-V132 WeakPolarHBondContact O-CA 3.4Å; Y125-V132 HydrophobicContact CD2-CG2 3.7Å; Y125-V132 HydrophobicContact CE2-CG2 4.39Å; V132-W144 PolarHBondContact N-O 2.92Å; V132-W144 PolarHBondContact O-N 3.11Å; V132-V146 HydrophobicContact CB-CG2 4.2Å; V132-V146 HydrophobicContact CG2-CG2 3.53Å
133A98.6Very high97.6Very high0 Ų033.4 Ų33.40%015%0.152CC..EExtended strand (participates in β ladder)trans-119.6145.8169.500000110.7L123 A124 I141 F142 L143 L174 M176 I183L123-A133 CarbonylContact C-O 3.38Å; L123-A133 VanDerWaalsContact CA-O 3.25Å; L123-A133 WeakPolarHBondContact CA-O 3.19Å; L123-A133 WeakPolarHBondContact CD2-O 3.46Å; A124-A133 HydrophobicContact CB-CB 4.35Å; A124-A133 PolarHBondContact N-O 3.46Å; A124-A133 PolarHBondContact O-N 3.31Å; A133-I141 HydrophobicContact CB-CG2 4.26Å; A133-F142 CarbonylContact C-O 3.56Å; A133-F142 WeakPolarHBondContact CA-O 3.3Å; A133-L143 HydrophobicContact CB-CD2 3.6Å; A133-L174 HydrophobicContact CB-CD2 3.58Å; A133-M176 HydrophobicContact CB-CE 3.73Å; A133-I183 HydrophobicContact CB-CD1 3.5Å; A133-I183 VanDerWaalsContact CB-CD1 3.5Å
134S98.8Very high97.5Very high0 Ų033.3 Ų33.30%015%0.151CC..EExtended strand (participates in β ladder)trans-124.6139.2175.364.20000111.3H116 I141 F142 W144H116-S134 PolarHBondContact CE1-O 2.83Å; H116-S134 WeakPolarHBondContact NE2-CB 3.03Å; H116-S134 PolarHBondContact NE2-O 2.62Å; H116-S134 PolarHBondContact NE2-OG 3.25Å; S134-I141 CarbonylContact O-C 3.54Å; S134-I141 VanDerWaalsContact O-CA 3.26Å; S134-I141 WeakPolarHBondContact O-CA 3.32Å; S134-F142 PolarHBondContact N-O 2.97Å; S134-F142 PolarHBondContact O-N 3.37Å; S134-W144 PolarHBondContact OG-NE1 3.26Å
135A98.8Very high97.4Very high0 Ų035.8 Ų35.80%016%0.164CC..EExtended strand (participates in β ladder)trans-144.2153.1-178.800000112.1V120 K121 A122 Q140 I141 I171 L174V120-A135 WeakPolarHBondContact CG1-O 3.04Å; K121-A135 PolarHBondContact N-O 2.9Å; A122-A135 PolarHBondContact N-O 3.42Å; A122-A135 VanDerWaalsContact N-O 3.1Å; A122-A135 PolarHBondContact O-N 3.35Å; A135-Q140 WeakPolarHBondContact CA-O 3.32Å; A135-I141 HydrophobicContact CB-CG1 3.92Å; A135-I171 HydrophobicContact CB-CB 4.14Å; A135-I171 HydrophobicContact CB-CD1 3.97Å; A135-I171 HydrophobicContact CB-CG2 3.72Å; A135-L174 HydrophobicContact CB-CD1 4.05Å; A135-L174 HydrophobicContact CB-CD2 3.84Å; A135-L174 HydrophobicContact CB-CG 4.38Å
136G98.2Very high97.3Very high0 Ų033.6 Ų33.60%016%0.155CC..EExtended strand (participates in β ladder)trans-157.8-164.3-174.900000115.8Y119 D138 R139 I171Y119-G136 CarbonylContact O-C 3.6Å; Y119-G136 WeakPolarHBondContact O-CA 3.5Å; G136-D138 PolarHBondContact O-N 3.14Å; G136-R139 PolarHBondContact O-N 3.04Å; G136-I171 PolarHBondContact O-N 3.13Å
137L98.5Very high97.1Very high29 Ų2937.6 Ų37.615%0.15218%0.176CC..THydrogen-bonded Turntrans-68.7-20.2-179-57.5-173.7000112.8D118 Y119 K121 R139 S170 Y172D118-L137 HydrophobicContact CB-CB 3.98Å; Y119-L137 HydrophobicContact CD2-CD1 3.89Å; Y119-L137 HydrophobicContact CG-CD1 4.01Å; Y119-L137 PolarHBondContact O-N 3.23Å; K121-L137 HydrophobicContact CD-CD2 4.23Å; K121-L137 HydrophobicContact CD-CG 4.26Å; K121-L137 HydrophobicContact CG-CD2 3.75Å; K121-L137 HydrophobicContact CG-CG 3.95Å; L137-R139 PolarHBondContact O-N 2.93Å; L137-S170 PolarHBondContact O-OG 2.86Å; L137-S170 VanDerWaalsContact O-OG 3.05Å; L137-Y172 HydrophobicContact CD2-CE1 4.49Å; L137-Y172 HydrophobicContact CD2-CE2 3.95Å
138D97.1Very high97Very high25 Ų2535.3 Ų35.313%0.13417%0.172CC..THydrogen-bonded Turntrans-71.8-1.1174.373.2-12.2000113.7H116 K117 D118 G136 Q140H116-D138 VanDerWaalsContact CA-OD2 3.27Å; H116-D138 WeakPolarHBondContact CA-OD2 3.07Å; H116-D138 IonicContact CE1-OD1 2.68Å; H116-D138 IonicContact CG-OD2 3.34Å; H116-D138 IonicContact ND1-OD1 4Å; H116-D138 PolarHBondContact ND1-OD1 3.04Å; H116-D138 IonicContact ND1-OD2 2.76Å; H116-D138 PolarHBondContact ND1-OD2 3.47Å; K117-D138 HydrophobicContact CB-CB 4.23Å; K117-D138 PolarHBondContact N-OD2 2.74Å; K117-D138 VanDerWaalsContact N-OD2 3.1Å; D118-D138 HydrophobicContact CB-CB 3.87Å; G136-D138 PolarHBondContact O-N 3.14Å; D138-Q140 PolarHBondContact O-N 3.46Å; D138-Q140 VanDerWaalsContact O-N 3.13Å; D138-Q140 PolarHBondContact OD1-N 3.45Å; D138-Q140 VanDerWaalsContact OD1-N 3.11Å; D138-Q140 PolarHBondContact OD2-NE2 2.96Å
139R98.1Very high97Very high126 Ų12631.6 Ų31.648%0.47515%0.152SC..SBendtrans67.96.7175.7-41.1175.9-179.2164.3-1.2113.6G136 L137 N167G136-R139 PolarHBondContact O-N 3.04Å; L137-R139 PolarHBondContact O-N 2.93Å; R139-N167 HydrophobicContact CB-CB 4.41Å
140Q97.6Very high96.9Very high58 Ų5827.8 Ų27.827%0.27114%0.139SC..  trans-94.1149.9178.5-60.2-175.2108.500110.1A135 D138 F142A135-Q140 WeakPolarHBondContact CA-O 3.32Å; D138-Q140 PolarHBondContact O-N 3.46Å; D138-Q140 VanDerWaalsContact O-N 3.13Å; D138-Q140 PolarHBondContact OD1-N 3.45Å; D138-Q140 VanDerWaalsContact OD1-N 3.11Å; D138-Q140 PolarHBondContact OD2-NE2 2.96Å; Q140-F142 HydrophobicContact CB-CD2 4.45Å; Q140-F142 HydrophobicContact CB-CE2 3.82Å; Q140-F142 HydrophobicContact CB-CZ 4.17Å
141I98.7Very high96.6Very high0 Ų029 Ų290%015%0.154CC..EExtended strand (participates in β ladder)trans-122.8126.5168.2-53.9170.6000106.7A133 S134 A135 S163 L164 N167 I171 L174 I183 W195A133-I141 HydrophobicContact CB-CG2 4.26Å; S134-I141 CarbonylContact O-C 3.54Å; S134-I141 VanDerWaalsContact O-CA 3.26Å; S134-I141 WeakPolarHBondContact O-CA 3.32Å; A135-I141 HydrophobicContact CB-CG1 3.92Å; I141-S163 CarbonylContact O-C 3.55Å; I141-S163 WeakPolarHBondContact O-CA 3.37Å; I141-L164 HydrophobicContact CB-CB 4.09Å; I141-L164 HydrophobicContact CB-CD1 4.43Å; I141-L164 HydrophobicContact CB-CG 4.47Å; I141-L164 HydrophobicContact CD1-CB 4.44Å; I141-L164 HydrophobicContact CG2-CD1 4.06Å; I141-L164 HydrophobicContact CG2-CG 4.45Å; I141-L164 PolarHBondContact O-N 2.61Å; I141-N167 WeakPolarHBondContact CD1-ND2 3.36Å; I141-I171 HydrophobicContact CD1-CD1 4.1Å; I141-I171 HydrophobicContact CG1-CD1 3.58Å; I141-L174 HydrophobicContact CD1-CD1 3.93Å; I141-L174 HydrophobicContact CG1-CD1 4.33Å; I141-L174 HydrophobicContact CG2-CD1 4.27Å; I141-L174 HydrophobicContact CG2-CD2 4.21Å; I141-I183 HydrophobicContact CG2-CD1 4.02Å; I141-W195 HydrophobicContact CD1-CE3 4.49Å; I141-W195 HydrophobicContact CD1-CH2 3.93Å; I141-W195 HydrophobicContact CD1-CZ3 3.88Å
142F98.5Very high96.2Very high13 Ų1328.8 Ų28.86%0.05715%0.153CC..EExtended strand (participates in β ladder)trans-110.3143.9173.1-65.3-77.8000110.6H116 A133 S134 Q140 W144 S162H116-F142 AromaticContact CD2-CD2 3.95Å; H116-F142 AromaticContact CE1-CD2 3.53Å; H116-F142 AromaticContact CE1-CE2 3.94Å; H116-F142 AromaticContact ND1-CD2 3.94Å; H116-F142 AromaticContact ND1-CE2 3.89Å; H116-F142 AromaticContact NE2-CD2 3.54Å; A133-F142 CarbonylContact C-O 3.56Å; A133-F142 WeakPolarHBondContact CA-O 3.3Å; S134-F142 PolarHBondContact N-O 2.97Å; S134-F142 PolarHBondContact O-N 3.37Å; Q140-F142 HydrophobicContact CB-CD2 4.45Å; Q140-F142 HydrophobicContact CB-CE2 3.82Å; Q140-F142 HydrophobicContact CB-CZ 4.17Å; F142-W144 HydrophobicContact CB-CD2 4.49Å; F142-W144 HydrophobicContact CB-CH2 4.31Å; F142-W144 HydrophobicContact CB-CZ2 3.43Å; F142-W144 VanDerWaalsContact CB-CZ2 3.43Å; F142-W144 HydrophobicContact CD2-CZ2 4.42Å; F142-W144 AromaticContact CG-CZ2 3.95Å; F142-W144 HydrophobicContact CG-CZ2 3.95Å; F142-S162 WeakPolarHBondContact CA-O 3.48Å
143L98.2Very high95.7Very high11 Ų1132.3 Ų32.36%0.05818%0.175CC..EExtended strand (participates in β ladder)trans-107.7138175.9-58.3177.6000109.9A133 S162 L164 M176 I183 P197A133-L143 HydrophobicContact CB-CD2 3.6Å; L143-S162 PolarHBondContact N-O 2.83Å; L143-L164 HydrophobicContact CD1-CD1 4.49Å; L143-L164 HydrophobicContact CD1-CD2 4.14Å; L143-L164 HydrophobicContact CD1-CG 4.35Å; L143-L164 HydrophobicContact CD2-CD1 4.29Å; L143-L164 HydrophobicContact CG-CG 4.44Å; L143-M176 HydrophobicContact CD2-CE 4.05Å; L143-I183 HydrophobicContact CD2-CD1 4.12Å; L143-P197 HydrophobicContact CD1-CB 3.83Å; L143-P197 VanDerWaalsContact CD1-O 3.26Å; L143-P197 WeakPolarHBondContact CD1-O 3.39Å; L143-P197 HydrophobicContact CD2-CB 4.3Å
144W97.3Very high94.8Very high4 Ų437.2 Ų37.22%0.01522%0.215CC..EExtended strand (participates in β ladder)trans-137.6118.7-172.1-47.4101.7000110.8L113 T115 L131 V132 S134 F142 V146 L149 V159 T161L113-W144 HydrophobicContact CB-CH2 4.21Å; L113-W144 HydrophobicContact CB-CZ2 4.45Å; L113-W144 HydrophobicContact CD1-CD2 3.86Å; L113-W144 HydrophobicContact CD1-CE3 3.85Å; L113-W144 HydrophobicContact CD1-CG 4.47Å; L113-W144 HydrophobicContact CD1-CH2 4.02Å; L113-W144 HydrophobicContact CD1-CZ2 4.06Å; L113-W144 HydrophobicContact CD1-CZ3 3.94Å; L113-W144 HydrophobicContact CD2-CZ3 4.4Å; T115-W144 HydrophobicContact CG2-CH2 3.74Å; T115-W144 HydrophobicContact CG2-CZ2 4.49Å; T115-W144 WeakPolarHBondContact OG1-CH2 3.46Å; T115-W144 WeakPolarHBondContact OG1-CZ2 3.36Å; L131-W144 WeakPolarHBondContact CD1-O 3.35Å; V132-W144 PolarHBondContact N-O 2.92Å; V132-W144 PolarHBondContact O-N 3.11Å; S134-W144 PolarHBondContact OG-NE1 3.26Å; F142-W144 HydrophobicContact CB-CD2 4.49Å; F142-W144 HydrophobicContact CB-CH2 4.31Å; F142-W144 HydrophobicContact CB-CZ2 3.43Å; F142-W144 VanDerWaalsContact CB-CZ2 3.43Å; F142-W144 HydrophobicContact CD2-CZ2 4.42Å; F142-W144 AromaticContact CG-CZ2 3.95Å; F142-W144 HydrophobicContact CG-CZ2 3.95Å; W144-V146 PolarHBondContact O-N 2.76Å; W144-L149 HydrophobicContact CB-CD1 3.75Å; W144-L149 HydrophobicContact CB-CG 4.39Å; W144-L149 HydrophobicContact CE3-CD2 4.3Å; W144-L149 HydrophobicContact CG-CD1 4.37Å; W144-V159 HydrophobicContact CE3-CG2 4.12Å; W144-V159 HydrophobicContact CZ3-CG1 4.13Å; W144-V159 HydrophobicContact CZ3-CG2 3.99Å; W144-T161 HydrophobicContact CH2-CG2 3.86Å; W144-T161 HydrophobicContact CZ3-CG2 3.87Å
145D95.9Very high93.9Very high58 Ų5842.7 Ų42.731%0.3125%0.254SS..EExtended strand (participates in β ladder)trans-75.1118.5165.5167.733.5000109.2N147 T148 L149D145-N147 PolarHBondContact O-N 2.56Å; D145-N147 PolarHBondContact OD1-N 3.44Å; D145-N147 VanDerWaalsContact OD1-N 3.1Å; D145-N147 PolarHBondContact OD1-ND2 2.91Å; D145-T148 PolarHBondContact O-N 3.06Å; D145-T148 WeakPolarHBondContact OD2-CB 3.48Å; D145-T148 PolarHBondContact OD2-N 2.87Å; D145-T148 VanDerWaalsContact OD2-N 3.13Å; D145-T148 PolarHBondContact OD2-OG1 3.03Å; D145-L149 WeakPolarHBondContact O-CG 3.13Å; D145-L149 PolarHBondContact O-N 3.14Å; D145-L149 VanDerWaalsContact O-N 3.08Å
146V95.3Very high93.2Very high0 Ų046.3 Ų46.30%027%0.273CS..Hα-helixtrans-63.4-34.6-177177.50000110.9C85 T89 E130 V132 W144 L149 T150C85-V146 WeakPolarHBondContact SG-CG1 3.4Å; T89-V146 HydrophobicContact CG2-CG1 3.98Å; E130-V146 HydrophobicContact CB-CB 4.35Å; E130-V146 WeakPolarHBondContact O-CB 3.35Å; E130-V146 VanDerWaalsContact O-CG2 3.24Å; E130-V146 WeakPolarHBondContact O-CG2 3.24Å; E130-V146 PolarHBondContact O-N 2.91Å; V132-V146 HydrophobicContact CB-CG2 4.2Å; V132-V146 HydrophobicContact CG2-CG2 3.53Å; W144-V146 PolarHBondContact O-N 2.76Å; V146-L149 WeakPolarHBondContact O-CB 3.37Å; V146-L149 PolarHBondContact O-N 3.26Å; V146-T150 HydrophobicContact CG1-CG2 4.1Å; V146-T150 WeakPolarHBondContact O-CG2 3.49Å; V146-T150 PolarHBondContact O-N 3.06Å; V146-T150 PolarHBondContact O-OG1 3.08Å
147N93.9Very high92.4Very high85 Ų8552 Ų5246%0.45530%0.303SS..Hα-helixtrans-64.2-46.7-179.6-60.1-64000110.8D145 L149 T150 A151D145-N147 PolarHBondContact O-N 2.56Å; D145-N147 PolarHBondContact OD1-N 3.44Å; D145-N147 VanDerWaalsContact OD1-N 3.1Å; D145-N147 PolarHBondContact OD1-ND2 2.91Å; N147-L149 VanDerWaalsContact C-N 3.32Å; N147-L149 PolarHBondContact O-N 3.44Å; N147-T150 PolarHBondContact O-N 2.68Å; N147-T150 PolarHBondContact O-OG1 2.99Å; N147-A151 WeakPolarHBondContact O-CB 3.44Å; N147-A151 PolarHBondContact O-N 3.44Å; N147-A151 VanDerWaalsContact O-N 3.11Å
148T93.3Very high91.5Very high62 Ų6255.6 Ų55.638%0.3833%0.326SS..Hα-helixtrans-56.1-45.2172.3-61.70000111.6D145 T150 A151D145-T148 PolarHBondContact O-N 3.06Å; D145-T148 WeakPolarHBondContact OD2-CB 3.48Å; D145-T148 PolarHBondContact OD2-N 2.87Å; D145-T148 VanDerWaalsContact OD2-N 3.13Å; D145-T148 PolarHBondContact OD2-OG1 3.03Å; T148-T150 PolarHBondContact O-N 2.76Å; T148-A151 PolarHBondContact O-N 2.91Å
149L93.9Very high90.9Very high3 Ų356.5 Ų56.52%0.01633%0.333CS..Hα-helixtrans-62.8-41.2178.4-69.9-176.4000113.1I91 V101 L113 W144 D145 V146 N147 A151 L152 V159I91-L149 HydrophobicContact CD1-CD1 4.27Å; V101-L149 HydrophobicContact CG2-CB 4.2Å; V101-L149 HydrophobicContact CG2-CD1 3.93Å; V101-L149 HydrophobicContact CG2-CG 4.5Å; L113-L149 HydrophobicContact CD1-CD1 3.99Å; L113-L149 HydrophobicContact CD1-CD2 3.87Å; L113-L149 HydrophobicContact CD2-CD2 3.86Å; L113-L149 HydrophobicContact CG-CD2 4.46Å; W144-L149 HydrophobicContact CB-CD1 3.75Å; W144-L149 HydrophobicContact CB-CG 4.39Å; W144-L149 HydrophobicContact CE3-CD2 4.3Å; W144-L149 HydrophobicContact CG-CD1 4.37Å; D145-L149 WeakPolarHBondContact O-CG 3.13Å; D145-L149 PolarHBondContact O-N 3.14Å; D145-L149 VanDerWaalsContact O-N 3.08Å; V146-L149 WeakPolarHBondContact O-CB 3.37Å; V146-L149 PolarHBondContact O-N 3.26Å; N147-L149 VanDerWaalsContact C-N 3.32Å; N147-L149 PolarHBondContact O-N 3.44Å; L149-A151 VanDerWaalsContact C-N 3.25Å; L149-A151 PolarHBondContact O-N 3.35Å; L149-L152 HydrophobicContact CD2-CD1 4.13Å; L149-L152 WeakPolarHBondContact O-CB 3.45Å; L149-L152 WeakPolarHBondContact O-CG 3.45Å; L149-L152 PolarHBondContact O-N 3.09Å; L149-V159 HydrophobicContact CD2-CG2 3.91Å
150T91.4Very high90.2Very high47 Ų4756.7 Ų56.729%0.28835%0.348SS..Hα-helixtrans-73.6-17.5179.957.30000113.6T89 V146 N147 T148 L152T89-T150 HydrophobicContact CG2-CG2 3.84Å; V146-T150 HydrophobicContact CG1-CG2 4.1Å; V146-T150 WeakPolarHBondContact O-CG2 3.49Å; V146-T150 PolarHBondContact O-N 3.06Å; V146-T150 PolarHBondContact O-OG1 3.08Å; N147-T150 PolarHBondContact O-N 2.68Å; N147-T150 PolarHBondContact O-OG1 2.99Å; T148-T150 PolarHBondContact O-N 2.76Å; T150-L152 VanDerWaalsContact C-N 3.35Å
151A91.7Very high89.6Confident55 Ų5557.7 Ų57.746%0.45536%0.358SS..THydrogen-bonded Turntrans-88.61176.300000113.6N147 T148 L149N147-A151 WeakPolarHBondContact O-CB 3.44Å; N147-A151 PolarHBondContact O-N 3.44Å; N147-A151 VanDerWaalsContact O-N 3.11Å; T148-A151 PolarHBondContact O-N 2.91Å; L149-A151 VanDerWaalsContact C-N 3.25Å; L149-A151 PolarHBondContact O-N 3.35Å
152L89.2Confident89.2Confident27 Ų2759.9 Ų59.914%0.14137%0.374CS..  trans-66.3134176.2-67173.4000110.7L149 T150 N156L149-L152 HydrophobicContact CD2-CD1 4.13Å; L149-L152 WeakPolarHBondContact O-CB 3.45Å; L149-L152 WeakPolarHBondContact O-CG 3.45Å; L149-L152 PolarHBondContact O-N 3.09Å; T150-L152 VanDerWaalsContact C-N 3.35Å; L152-N156 WeakPolarHBondContact CA-O 3.14Å; L152-N156 VanDerWaalsContact CD2-O 3.26Å; L152-N156 WeakPolarHBondContact CD2-O 3.35Å
153T86.7Confident88.9Confident76 Ų7662.2 Ų62.247%0.46639%0.392SS..  trans-136.8176.5177.767.70000109.8S155 N156 N157T153-S155 PolarHBondContact O-N 2.83Å; T153-S155 PolarHBondContact OG1-N 3.3Å; T153-S155 PolarHBondContact OG1-OG 2.99Å; T153-S155 VanDerWaalsContact OG1-OG 3.11Å; T153-N156 PolarHBondContact N-O 3.18Å; T153-N156 CarbonylContact O-C 3.54Å; T153-N156 PolarHBondContact O-N 2.93Å; T153-N156 PolarHBondContact OG1-N 3.42Å; T153-N156 VanDerWaalsContact OG1-N 3.08Å; T153-N157 PolarHBondContact O-N 2.86Å
154A80.7Confident88.7Confident102 Ų10261.9 Ų61.984%0.84339%0.39SS*.SBendtrans-58.7-32.3173.900000112.9
155S79.8Confident88.4Confident116 Ų11665.4 Ų65.481%0.81142%0.415SS*.SBendtrans-88.6-23.217854.30000114T153T153-S155 PolarHBondContact O-N 2.83Å; T153-S155 PolarHBondContact OG1-N 3.3Å; T153-S155 PolarHBondContact OG1-OG 2.99Å; T153-S155 VanDerWaalsContact OG1-OG 3.11Å
156N83.3Confident88.2Confident75 Ų7563.8 Ų63.840%0.40141%0.413SS..  trans-121.177.4175.5-175.731.1000110L152 T153L152-N156 WeakPolarHBondContact CA-O 3.14Å; L152-N156 VanDerWaalsContact CD2-O 3.26Å; L152-N156 WeakPolarHBondContact CD2-O 3.35Å; T153-N156 PolarHBondContact N-O 3.18Å; T153-N156 CarbonylContact O-C 3.54Å; T153-N156 PolarHBondContact O-N 2.93Å; T153-N156 PolarHBondContact OG1-N 3.42Å; T153-N156 VanDerWaalsContact OG1-N 3.08Å
157N81.6Confident88.3Confident120 Ų12064.5 Ų64.564%0.64242%0.416SS*.  trans-106.86.6-172.967.1-6.2000113.7T153T153-N157 PolarHBondContact O-N 2.86Å
158T79.4Confident88.4Confident104 Ų10467.6 Ų67.664%0.63843%0.426SS*.  trans-95129.1179.4570000111
159V85.3Confident88.6Confident45 Ų4567.3 Ų67.327%0.27342%0.422SS..  trans-116.9130.7172.965.70000109.8L113 W144 L149L113-V159 HydrophobicContact CD2-CG1 4.28Å; W144-V159 HydrophobicContact CE3-CG2 4.12Å; W144-V159 HydrophobicContact CZ3-CG1 4.13Å; W144-V159 HydrophobicContact CZ3-CG2 3.99Å; L149-V159 HydrophobicContact CD2-CG2 3.91Å
160T83Confident88.8Confident129 Ų12968.2 Ų68.279%0.79143%0.428SS*.PPolyproline II helixtrans-77.8132.5171.643.40000109.5
161T84.1Confident89.2Confident79 Ų7966 Ų6649%0.48542%0.415SS..PPolyproline II helixtrans-102.2124.1-178.9460000109.7T115 W144T115-T161 HydrophobicContact CG2-CG2 3.7Å; W144-T161 HydrophobicContact CH2-CG2 3.86Å; W144-T161 HydrophobicContact CZ3-CG2 3.87Å
162S91.1Very high89.5Confident46 Ų4667 Ų6732%0.32241%0.407SS..EExtended strand (participates in β ladder)trans-104135.2164.6-179.20000108.4F142 L143 C200F142-S162 WeakPolarHBondContact CA-O 3.48Å; L143-S162 PolarHBondContact N-O 2.83Å; S162-C200 PolarHBondContact OG-SG 2.92Å; S162-C200 VanDerWaalsContact OG-SG 3.32Å
163S93Very high90Very high63 Ų6366 Ų6644%0.44140%0.402SS..EExtended strand (participates in β ladder)trans-131144.9-176.371.60000112.5I141I141-S163 CarbonylContact O-C 3.55Å; I141-S163 WeakPolarHBondContact O-CA 3.37Å
164L93.9Very high90.5Very high3 Ų363 Ų632%0.01638%0.383CS..EExtended strand (participates in β ladder)trans-104.7123.7174.3-49.3174.7000109.4I141 L143 I183 W195 C200I141-L164 HydrophobicContact CB-CB 4.09Å; I141-L164 HydrophobicContact CB-CD1 4.43Å; I141-L164 HydrophobicContact CB-CG 4.47Å; I141-L164 HydrophobicContact CD1-CB 4.44Å; I141-L164 HydrophobicContact CG2-CD1 4.06Å; I141-L164 HydrophobicContact CG2-CG 4.45Å; I141-L164 PolarHBondContact O-N 2.61Å; L143-L164 HydrophobicContact CD1-CD1 4.49Å; L143-L164 HydrophobicContact CD1-CD2 4.14Å; L143-L164 HydrophobicContact CD1-CG 4.35Å; L143-L164 HydrophobicContact CD2-CD1 4.29Å; L143-L164 HydrophobicContact CG-CG 4.44Å; L164-I183 HydrophobicContact CD1-CD1 4.02Å; L164-I183 HydrophobicContact CD1-CG2 3.54Å; L164-W195 HydrophobicContact CB-CD2 4.45Å; L164-W195 HydrophobicContact CB-CG 4.44Å; L164-W195 HydrophobicContact CD1-CB 4.11Å; L164-W195 HydrophobicContact CD1-CD2 4.33Å; L164-W195 HydrophobicContact CD1-CG 4.16Å; L164-W195 HydrophobicContact CD2-CB 4.45Å; L164-W195 HydrophobicContact CD2-CG 4.5Å; L164-C200 HydrophobicContact CD2-CB 3.61Å
165S90.2Very high91.4Very high78 Ų7858.5 Ų58.555%0.54535%0.347SS..  trans-100.2156.1177.870.20000111.8W195 K202S165-W195 PolarHBondContact O-NE1 3.39Å; S165-W195 VanDerWaalsContact O-NE1 3.11Å; S165-K202 WeakPolarHBondContact O-CE 3.43Å
166G92.1Very high92.2Very high25 Ų2553.7 Ų53.726%0.25831%0.312SS..  trans132.7-18.5166.900000115.7K168 R193G166-K168 PolarHBondContact O-N 3.05Å; G166-R193 PolarHBondContact O-NE 2.78Å; G166-R193 PolarHBondContact O-NH1 3.1Å; G166-R193 VanDerWaalsContact O-NH1 3.16Å; G166-R193 PolarHBondContact O-NH2 2.81Å
167N95.8Very high92.7Very high15 Ų1550.2 Ų50.28%0.0829%0.293CS..  trans-61.6131172.2-64.5-74.5000109.8R139 I141 I171 S185 R193 W195R139-N167 HydrophobicContact CB-CB 4.41Å; I141-N167 WeakPolarHBondContact CD1-ND2 3.36Å; N167-I171 HydrophobicContact CB-CD1 4.06Å; N167-I171 HydrophobicContact CB-CG1 4.14Å; N167-I171 WeakPolarHBondContact ND2-CD1 3.34Å; N167-S185 PolarHBondContact OD1-OG 3.44Å; N167-R193 WeakPolarHBondContact OD1-CD 3.43Å; N167-W195 WeakPolarHBondContact ND2-CH2 3.36Å
168K96.5Very high93.3Very high150 Ų15046.8 Ų46.865%0.65227%0.273SS*.  trans-93.2-15.9178.9-65.9-175.2176.7-171.10113.1G166 E189G166-K168 PolarHBondContact O-N 3.05Å; K168-E189 HydrophobicContact CB-CG 4.43Å; K168-E189 PolarHBondContact N-OE2 3.25Å; K168-E189 VanDerWaalsContact N-OE2 3.12Å
169D98Very high93.8Very high55 Ų5545.8 Ų45.829%0.29426%0.262SS..SBendtrans-143.2172-174.7-151.1-5.9000111.5T188 E189D169-T188 WeakPolarHBondContact CB-OG1 3.44Å; D169-T188 PolarHBondContact OD1-OG1 2.84Å; D169-T188 WeakPolarHBondContact OD2-CB 3.44Å; D169-T188 PolarHBondContact OD2-OG1 2.99Å; D169-E189 HydrophobicContact CB-CB 4.21Å
170S98.5Very high94.2Very high22 Ų2243.7 Ų43.715%0.15425%0.25CC..  trans-60.5133.2-173.1-66.40000113.2L137 Y172 S187 T188L137-S170 PolarHBondContact O-OG 2.86Å; L137-S170 VanDerWaalsContact O-OG 3.05Å; S170-Y172 WeakPolarHBondContact O-CD2 3.44Å; S170-S187 WeakPolarHBondContact O-CA 3.42Å; S170-S187 WeakPolarHBondContact O-CB 3.5Å; S170-T188 PolarHBondContact O-N 3.44Å
171I98.8Very high94.7Very high0 Ų039.5 Ų39.50%022%0.224CC..EExtended strand (participates in β ladder)trans-91.3132.8-174.5-54.6165.6000109.4K121 A135 G136 I141 N167 S173 G186K121-I171 WeakPolarHBondContact CB-O 3.37Å; A135-I171 HydrophobicContact CB-CB 4.14Å; A135-I171 HydrophobicContact CB-CD1 3.97Å; A135-I171 HydrophobicContact CB-CG2 3.72Å; G136-I171 PolarHBondContact O-N 3.13Å; I141-I171 HydrophobicContact CD1-CD1 4.1Å; I141-I171 HydrophobicContact CG1-CD1 3.58Å; N167-I171 HydrophobicContact CB-CD1 4.06Å; N167-I171 HydrophobicContact CB-CG1 4.14Å; N167-I171 WeakPolarHBondContact ND2-CD1 3.34Å; I171-S173 WeakPolarHBondContact CG2-O 3.46Å; I171-G186 WeakPolarHBondContact CG2-O 3.25Å
172Y98.8Very high95.3Very high77 Ų7736.3 Ų36.330%0.30221%0.205SC..EExtended strand (participates in β ladder)trans-118.5-18.8-178.2-81.2-96.5000113.6L137 S170 G186 T188 N212L137-Y172 HydrophobicContact CD2-CE1 4.49Å; L137-Y172 HydrophobicContact CD2-CE2 3.95Å; S170-Y172 WeakPolarHBondContact O-CD2 3.44Å; Y172-G186 PolarHBondContact N-O 3.02Å; Y172-T188 HydrophobicContact CD2-CG2 4.02Å; Y172-T188 HydrophobicContact CE2-CG2 3.62Å; Y172-N212 VanDerWaalsContact CD2-ND2 3.27Å; Y172-N212 WeakPolarHBondContact CD2-ND2 3.46Å; Y172-N212 WeakPolarHBondContact CD2-OD1 3.26Å; Y172-N212 VanDerWaalsContact CG-ND2 3.28Å
173S98.8Very high95.6Very high5 Ų534.1 Ų34.14%0.03519%0.189CC..EExtended strand (participates in β ladder)trans-144.1150.5176.955.60000111.8I171 G186 V213 K214 L216I171-S173 WeakPolarHBondContact CG2-O 3.46Å; S173-G186 PolarHBondContact N-O 2.96Å; S173-G186 VanDerWaalsContact N-O 3.08Å; S173-G186 PolarHBondContact O-N 2.85Å; S173-G186 WeakPolarHBondContact OG-CA 3.46Å; S173-V213 PolarHBondContact OG-O 3.06Å; S173-K214 VanDerWaalsContact CB-C 3.48Å; S173-K214 WeakPolarHBondContact CB-O 3.44Å; S173-L216 WeakPolarHBondContact OG-CD1 3.03Å
174L98.8Very high95.9Very high13 Ų1331.1 Ų31.17%0.06817%0.168CC..EExtended strand (participates in β ladder)trans-144.9138.3-179.4-159.469.3000108.4A122 A124 A133 A135 I141 I183 V184A122-L174 HydrophobicContact CB-CB 3.84Å; A124-L174 HydrophobicContact CB-CB 4.05Å; A124-L174 HydrophobicContact CB-CD2 3.82Å; A124-L174 HydrophobicContact CB-CG 3.69Å; A133-L174 HydrophobicContact CB-CD2 3.58Å; A135-L174 HydrophobicContact CB-CD1 4.05Å; A135-L174 HydrophobicContact CB-CD2 3.84Å; A135-L174 HydrophobicContact CB-CG 4.38Å; I141-L174 HydrophobicContact CD1-CD1 3.93Å; I141-L174 HydrophobicContact CG1-CD1 4.33Å; I141-L174 HydrophobicContact CG2-CD1 4.27Å; I141-L174 HydrophobicContact CG2-CD2 4.21Å; L174-I183 HydrophobicContact CD1-CD1 3.97Å; L174-I183 HydrophobicContact CD1-CG1 4.16Å; L174-I183 HydrophobicContact CD2-CD1 4.21Å; L174-I183 HydrophobicContact CG-CD1 4.12Å; L174-I183 HydrophobicContact CG-CG1 4.36Å; L174-V184 WeakPolarHBondContact CA-O 3.48Å
175A98.4Very high96.1Very high9 Ų931 Ų317%0.07417%0.168CC..EExtended strand (participates in β ladder)trans-142.3145.6173.500000110.6I183 V184 L216 L218A175-I183 CarbonylContact O-C 3.56Å; A175-I183 WeakPolarHBondContact O-CA 3.21Å; A175-I183 WeakPolarHBondContact O-CG1 3.14Å; A175-V184 PolarHBondContact N-O 2.68Å; A175-V184 PolarHBondContact O-N 2.98Å; A175-L216 HydrophobicContact CB-CB 3.58Å; A175-L218 HydrophobicContact CB-CD1 4.26Å; A175-L218 HydrophobicContact CB-CG 4.38Å
176M96.9Very high96.5Very high15 Ų1527.3 Ų27.37%0.07414%0.142CC..EExtended strand (participates in β ladder)trans-130.2142.7174.5-161-179.3-62.400107.9A124 A126 L131 A133 L143 V182 I183 P197A124-M176 HydrophobicContact CB-CB 3.98Å; A126-M176 HydrophobicContact CB-CG 3.97Å; A126-M176 HydrophobicContact CB-SD 3.37Å; A126-M176 WeakPolarHBondContact CB-SD 3.36Å; L131-M176 HydrophobicContact CD2-CE 4.08Å; L131-M176 HydrophobicContact CD2-SD 3.87Å; L131-M176 HydrophobicContact CG-CE 4.35Å; L131-M176 HydrophobicContact CG-SD 4.33Å; A133-M176 HydrophobicContact CB-CE 3.73Å; L143-M176 HydrophobicContact CD2-CE 4.05Å; M176-V182 WeakPolarHBondContact CA-O 3.17Å; M176-V182 VanDerWaalsContact CG-O 3.3Å; M176-V182 WeakPolarHBondContact CG-O 3.33Å; M176-I183 HydrophobicContact CE-CB 4.34Å; M176-I183 HydrophobicContact CE-CD1 3.85Å; M176-I183 HydrophobicContact CE-CG1 4.29Å; M176-I183 HydrophobicContact CG-CB 4.3Å; M176-P197 HydrophobicContact CE-CB 4.46Å; M176-P197 HydrophobicContact SD-CG 4.4Å
177N94.7Very high96.8Very high1 Ų126.1 Ų26.11%0.00513%0.129CC..  trans-74.3159.2175.171.9-30.2000110.2A126 M179 G180 T181 V182 L218 D221A126-N177 WeakPolarHBondContact CB-O 3.36Å; N177-M179 PolarHBondContact O-N 2.93Å; N177-M179 VanDerWaalsContact O-N 3.13Å; N177-G180 PolarHBondContact O-N 2.96Å; N177-G180 PolarHBondContact OD1-N 3.43Å; N177-T181 PolarHBondContact ND2-OG1 2.73Å; N177-T181 PolarHBondContact OD1-N 3.45Å; N177-V182 PolarHBondContact N-O 3.49Å; N177-V182 VanDerWaalsContact N-O 3.13Å; N177-V182 PolarHBondContact OD1-N 2.93Å; N177-V182 PolarHBondContact OD1-O 3.1Å; N177-L218 HydrophobicContact CB-CB 4.06Å; N177-L218 HydrophobicContact CB-CD1 4.22Å; N177-D221 PolarHBondContact ND2-OD2 3.26Å
178Q92.3Very high96.9Very high48 Ų4827.3 Ų27.322%0.22414%0.137CC..THydrogen-bonded Turntrans-56.8-35.5-174.5-168.6-179.4-25.700113.5K127 D128 G180 R220K127-Q178 HydrophobicContact CB-CG 4Å; K127-Q178 PolarHBondContact N-O 3.46Å; D128-Q178 WeakPolarHBondContact CB-O 3.19Å; D128-Q178 PolarHBondContact N-O 2.99Å; D128-Q178 VanDerWaalsContact N-O 3.1Å; D128-Q178 WeakPolarHBondContact OD1-CG 3.36Å; D128-Q178 PolarHBondContact OD1-NE2 3.29Å; Q178-G180 VanDerWaalsContact C-N 3.3Å; Q178-G180 PolarHBondContact O-N 3.34Å; Q178-R220 HydrophobicContact CB-CG 4.36Å
179M91.9Very high97Very high83 Ų8322.1 Ų22.141%0.40912%0.116SC..THydrogen-bonded Turntrans-75.9-13.8-179.6-65.4-177.266.100114.1N177 T181 D221N177-M179 PolarHBondContact O-N 2.93Å; N177-M179 VanDerWaalsContact O-N 3.13Å; M179-T181 HydrophobicContact CB-CG2 4.19Å; M179-D221 HydrophobicContact SD-CB 3.91Å
180G92.8Very high97Very high2 Ų223.9 Ų23.92%0.02112%0.12CC..SBendtrans6839.4-177.300000113.5A126 N177 Q178 P197A126-G180 VanDerWaalsContact CB-CA 3.41Å; N177-G180 PolarHBondContact O-N 2.96Å; N177-G180 PolarHBondContact OD1-N 3.43Å; Q178-G180 VanDerWaalsContact C-N 3.3Å; Q178-G180 PolarHBondContact O-N 3.34Å; G180-P197 VanDerWaalsContact O-CG 3.23Å; G180-P197 WeakPolarHBondContact O-CG 3.45Å
181T93.5Very high97Very high40 Ų4023.7 Ų23.725%0.24512%0.118CC..SBendtrans-108.9-17.5177.457.10000112.9N177 M179 P197N177-T181 PolarHBondContact ND2-OG1 2.73Å; N177-T181 PolarHBondContact OD1-N 3.45Å; M179-T181 HydrophobicContact CB-CG2 4.19Å; T181-P197 WeakPolarHBondContact O-CD 3.45Å
182V95.9Very high97Very high13 Ų1323.7 Ų23.78%0.07912%0.118CC..  trans-137.5130.9-179.5179.70000109.5M176 N177 V184 V194 L218 T227 L243M176-V182 WeakPolarHBondContact CA-O 3.17Å; M176-V182 VanDerWaalsContact CG-O 3.3Å; M176-V182 WeakPolarHBondContact CG-O 3.33Å; N177-V182 PolarHBondContact N-O 3.49Å; N177-V182 VanDerWaalsContact N-O 3.13Å; N177-V182 PolarHBondContact OD1-N 2.93Å; N177-V182 PolarHBondContact OD1-O 3.1Å; V182-V184 HydrophobicContact CG1-CG2 4.12Å; V182-V194 HydrophobicContact CG1-CG1 3.58Å; V182-L218 HydrophobicContact CG1-CD1 4.28Å; V182-L218 HydrophobicContact CG1-CD2 4.49Å; V182-T227 HydrophobicContact CG2-CG2 4.36Å; V182-L243 HydrophobicContact CG1-CD2 3.95Å
183I98Very high97Very high0 Ų021 Ų210%011%0.107CC..EExtended strand (participates in β ladder)trans-122.8136.2168.1-174.1177.8000109.9A133 I141 L143 L164 L174 A175 M176 V194 W195 P197A133-I183 HydrophobicContact CB-CD1 3.5Å; A133-I183 VanDerWaalsContact CB-CD1 3.5Å; I141-I183 HydrophobicContact CG2-CD1 4.02Å; L143-I183 HydrophobicContact CD2-CD1 4.12Å; L164-I183 HydrophobicContact CD1-CD1 4.02Å; L164-I183 HydrophobicContact CD1-CG2 3.54Å; L174-I183 HydrophobicContact CD1-CD1 3.97Å; L174-I183 HydrophobicContact CD1-CG1 4.16Å; L174-I183 HydrophobicContact CD2-CD1 4.21Å; L174-I183 HydrophobicContact CG-CD1 4.12Å; L174-I183 HydrophobicContact CG-CG1 4.36Å; A175-I183 CarbonylContact O-C 3.56Å; A175-I183 WeakPolarHBondContact O-CA 3.21Å; A175-I183 WeakPolarHBondContact O-CG1 3.14Å; M176-I183 HydrophobicContact CE-CB 4.34Å; M176-I183 HydrophobicContact CE-CD1 3.85Å; M176-I183 HydrophobicContact CE-CG1 4.29Å; M176-I183 HydrophobicContact CG-CB 4.3Å; I183-V194 WeakPolarHBondContact O-CA 3.46Å; I183-W195 HydrophobicContact CG2-CB 3.78Å; I183-W195 HydrophobicContact CG2-CE3 4.4Å; I183-W195 PolarHBondContact N-O 3.01Å; I183-W195 PolarHBondContact O-N 2.78Å; I183-P197 HydrophobicContact CG2-CB 4.25Å
184V98.6Very high96.9Very high0 Ų020.8 Ų20.80%011%0.106CC..EExtended strand (participates in β ladder)trans-122.7135.1179.4-174.40000109.9L174 A175 V182 L192 R193 V194 L216 L218L174-V184 WeakPolarHBondContact CA-O 3.48Å; A175-V184 PolarHBondContact N-O 2.68Å; A175-V184 PolarHBondContact O-N 2.98Å; V182-V184 HydrophobicContact CG1-CG2 4.12Å; V184-L192 HydrophobicContact CG1-CB 3.94Å; V184-L192 HydrophobicContact CG1-CD2 4.04Å; V184-L192 HydrophobicContact CG1-CG 4.18Å; V184-R193 CarbonylContact C-O 3.53Å; V184-R193 VanDerWaalsContact CA-O 3.26Å; V184-R193 WeakPolarHBondContact CA-O 3.33Å; V184-V194 HydrophobicContact CG1-CG2 4.41Å; V184-V194 HydrophobicContact CG2-CG1 4.1Å; V184-V194 HydrophobicContact CG2-CG2 4.05Å; V184-L216 HydrophobicContact CB-CD1 4.31Å; V184-L216 HydrophobicContact CG1-CD1 3.92Å; V184-L216 HydrophobicContact CG1-CD2 4.2Å; V184-L218 HydrophobicContact CG2-CD1 4.05Å; V184-L218 HydrophobicContact CG2-CD2 3.98Å; V184-L218 HydrophobicContact CG2-CG 4.39Å
185S98.8Very high96.9Very high0 Ų020.2 Ų20.20%010%0.103CC..EExtended strand (participates in β ladder)trans-111.2145170.470.60000112N167 L192 R193 W195N167-S185 PolarHBondContact OD1-OG 3.44Å; S185-L192 WeakPolarHBondContact O-CA 3.44Å; S185-R193 PolarHBondContact N-O 2.97Å; S185-R193 PolarHBondContact O-N 2.78Å; S185-W195 VanDerWaalsContact OG-CH2 3.28Å; S185-W195 WeakPolarHBondContact OG-CH2 3.41Å; S185-W195 VanDerWaalsContact OG-CZ3 3.24Å; S185-W195 WeakPolarHBondContact OG-CZ3 3.4Å
186G98.6Very high96.8Very high0 Ų021.3 Ų21.30%011%0.108CC..EExtended strand (participates in β ladder)trans-122.5134.7172.800000110.2I171 Y172 S173 V213 L216I171-G186 WeakPolarHBondContact CG2-O 3.25Å; Y172-G186 PolarHBondContact N-O 3.02Å; S173-G186 PolarHBondContact N-O 2.96Å; S173-G186 VanDerWaalsContact N-O 3.08Å; S173-G186 PolarHBondContact O-N 2.85Å; S173-G186 WeakPolarHBondContact OG-CA 3.46Å; G186-V213 CarbonylContact C-O 3.59Å; G186-L216 VanDerWaalsContact N-CD1 3.34Å
187S98.4Very high96.7Very high0 Ų021 Ų210%011%0.107CC..EExtended strand (participates in β ladder)trans-146.5176.3-169.165.70000112S170 E189 K190 N212 V213S170-S187 WeakPolarHBondContact O-CA 3.42Å; S170-S187 WeakPolarHBondContact O-CB 3.5Å; S187-E189 PolarHBondContact O-N 2.78Å; S187-E189 WeakPolarHBondContact OG-CB 3.19Å; S187-E189 PolarHBondContact OG-N 2.87Å; S187-E189 VanDerWaalsContact OG-N 3.15Å; S187-K190 PolarHBondContact O-N 2.91Å; S187-K190 VanDerWaalsContact O-N 3.12Å; S187-N212 PolarHBondContact O-OD1 2.95Å; S187-V213 PolarHBondContact O-N 2.8Å
188T98.3Very high96.7Very high40 Ų4029.7 Ų29.725%0.24514%0.139CC..THydrogen-bonded Turntrans-67.5-7168.148.20000113.1D169 S170 Y172 K190 N212D169-T188 WeakPolarHBondContact CB-OG1 3.44Å; D169-T188 PolarHBondContact OD1-OG1 2.84Å; D169-T188 WeakPolarHBondContact OD2-CB 3.44Å; D169-T188 PolarHBondContact OD2-OG1 2.99Å; S170-T188 PolarHBondContact O-N 3.44Å; Y172-T188 HydrophobicContact CD2-CG2 4.02Å; Y172-T188 HydrophobicContact CE2-CG2 3.62Å; T188-K190 WeakPolarHBondContact O-CG 3.41Å; T188-K190 PolarHBondContact O-N 3.47Å; T188-N212 HydrophobicContact CG2-CB 3.97Å; T188-N212 PolarHBondContact N-OD1 2.84Å
189E97.9Very high96.9Very high42 Ų4231.7 Ų31.720%0.19616%0.155CC..THydrogen-bonded Turntrans-67.7-12.6168.2-162.8-178.8168.200111.6K168 D169 S187 V191 R193K168-E189 HydrophobicContact CB-CG 4.43Å; K168-E189 PolarHBondContact N-OE2 3.25Å; K168-E189 VanDerWaalsContact N-OE2 3.12Å; D169-E189 HydrophobicContact CB-CB 4.21Å; S187-E189 PolarHBondContact O-N 2.78Å; S187-E189 WeakPolarHBondContact OG-CB 3.19Å; S187-E189 PolarHBondContact OG-N 2.87Å; S187-E189 VanDerWaalsContact OG-N 3.15Å; E189-V191 HydrophobicContact CG-CB 4.49Å; E189-V191 PolarHBondContact O-N 3.24Å; E189-R193 IonicContact OE1-CZ 2.89Å; E189-R193 IonicContact OE1-NE 2.72Å; E189-R193 PolarHBondContact OE1-NE 3.01Å; E189-R193 IonicContact OE1-NH2 3.67Å; E189-R193 PolarHBondContact OE1-NH2 3.08Å; E189-R193 IonicContact OE2-CZ 3.62Å; E189-R193 IonicContact OE2-NE 2.7Å; E189-R193 PolarHBondContact OE2-NE 2.83Å; E189-R193 IonicContact OE2-NH2 3Å; E189-R193 PolarHBondContact OE2-NH2 3.17Å
190K98.2Very high97.1Very high91 Ų9130 Ų3040%0.39615%0.15SC..SBendtrans66.6-0.7179.2-44169.5175.9-157.80114.1S187 T188 T210S187-K190 PolarHBondContact O-N 2.91Å; S187-K190 VanDerWaalsContact O-N 3.12Å; T188-K190 WeakPolarHBondContact O-CG 3.41Å; T188-K190 PolarHBondContact O-N 3.47Å; K190-T210 VanDerWaalsContact CD-O 3.25Å; K190-T210 WeakPolarHBondContact CD-O 3.42Å; K190-T210 VanDerWaalsContact CE-O 3.24Å; K190-T210 WeakPolarHBondContact CE-O 3.16Å; K190-T210 PolarHBondContact NZ-O 3.19Å
191V98.3Very high97.3Very high18 Ų1831.9 Ų31.911%0.10917%0.166CC..EExtended strand (participates in β ladder)trans-109.5132.5-179.9179.60000108.5E189 K205 K207E189-V191 HydrophobicContact CG-CB 4.49Å; E189-V191 PolarHBondContact O-N 3.24Å; V191-K205 HydrophobicContact CG1-CB 3.87Å; V191-K205 HydrophobicContact CG1-CG 4.48Å; V191-K207 HydrophobicContact CG1-CG 4.14Å; V191-K207 HydrophobicContact CG2-CG 3.9Å
192L98.7Very high97.5Very high0 Ų036.1 Ų36.10%018%0.181CC..EExtended strand (participates in β ladder)trans-81.5133.1171-72.962.2000108.4V184 S185 K205 L206 V213 L216 W241V184-L192 HydrophobicContact CG1-CB 3.94Å; V184-L192 HydrophobicContact CG1-CD2 4.04Å; V184-L192 HydrophobicContact CG1-CG 4.18Å; S185-L192 WeakPolarHBondContact O-CA 3.44Å; L192-K205 CarbonylContact O-C 3.52Å; L192-K205 WeakPolarHBondContact O-CA 3.37Å; L192-L206 HydrophobicContact CB-CB 4.13Å; L192-L206 HydrophobicContact CB-CD1 4.48Å; L192-L206 HydrophobicContact CD2-CD1 4.47Å; L192-L206 PolarHBondContact N-O 3.45Å; L192-L206 PolarHBondContact O-N 3.43Å; L192-V213 HydrophobicContact CD1-CG1 4.37Å; L192-V213 HydrophobicContact CD1-CG2 3.9Å; L192-L216 HydrophobicContact CD2-CD2 3.61Å; L192-L216 HydrophobicContact CG-CD2 4.04Å; L192-W241 HydrophobicContact CD1-CZ2 4.3Å
193R98.6Very high97.5Very high20 Ų2039.3 Ų39.38%0.07520%0.198CC..EExtended strand (participates in β ladder)trans-113141.8176.5-68.2173.4168.7-84.56.3109.3G166 N167 V184 S185 E189 W195 K205G166-R193 PolarHBondContact O-NE 2.78Å; G166-R193 PolarHBondContact O-NH1 3.1Å; G166-R193 VanDerWaalsContact O-NH1 3.16Å; G166-R193 PolarHBondContact O-NH2 2.81Å; N167-R193 WeakPolarHBondContact OD1-CD 3.43Å; V184-R193 CarbonylContact C-O 3.53Å; V184-R193 VanDerWaalsContact CA-O 3.26Å; V184-R193 WeakPolarHBondContact CA-O 3.33Å; S185-R193 PolarHBondContact N-O 2.97Å; S185-R193 PolarHBondContact O-N 2.78Å; E189-R193 IonicContact OE1-CZ 2.89Å; E189-R193 IonicContact OE1-NE 2.72Å; E189-R193 PolarHBondContact OE1-NE 3.01Å; E189-R193 IonicContact OE1-NH2 3.67Å; E189-R193 PolarHBondContact OE1-NH2 3.08Å; E189-R193 IonicContact OE2-CZ 3.62Å; E189-R193 IonicContact OE2-NE 2.7Å; E189-R193 PolarHBondContact OE2-NE 2.83Å; E189-R193 IonicContact OE2-NH2 3Å; E189-R193 PolarHBondContact OE2-NH2 3.17Å; R193-W195 HydrophobicContact CB-CE3 4.3Å; R193-W195 HydrophobicContact CB-CH2 3.11Å; R193-W195 HydrophobicContact CB-CZ2 3.78Å; R193-W195 HydrophobicContact CB-CZ3 3.42Å; R193-W195 VanDerWaalsContact CB-CZ3 3.42Å; R193-W195 HydrophobicContact CG-CH2 4.14Å; R193-W195 WeakPolarHBondContact O-CZ3 3.25Å; R193-K205 HydrophobicContact CG-CG 4.38Å
194V98.4Very high97.4Very high1 Ų140.7 Ų40.71%0.00620%0.204CC..EExtended strand (participates in β ladder)trans-128.4135.5-171.6-168.90000109.9V182 I183 V184 L203 M204 L206 L243V182-V194 HydrophobicContact CG1-CG1 3.58Å; I183-V194 WeakPolarHBondContact O-CA 3.46Å; V184-V194 HydrophobicContact CG1-CG2 4.41Å; V184-V194 HydrophobicContact CG2-CG1 4.1Å; V184-V194 HydrophobicContact CG2-CG2 4.05Å; V194-L203 HydrophobicContact CB-CB 4.35Å; V194-L203 HydrophobicContact CG1-CB 4.24Å; V194-L203 HydrophobicContact CG1-CD1 4.11Å; V194-L203 PolarHBondContact O-N 3.35Å; V194-M204 HydrophobicContact CB-CG 3.71Å; V194-M204 HydrophobicContact CG1-CG 4.4Å; V194-M204 HydrophobicContact CG2-CG 3.51Å; V194-M204 HydrophobicContact CG2-SD 4.33Å; V194-M204 PolarHBondContact N-O 3.34Å; V194-M204 VanDerWaalsContact N-O 3.09Å; V194-L206 HydrophobicContact CG2-CD1 4.31Å; V194-L206 HydrophobicContact CG2-CG 4.46Å; V194-L243 HydrophobicContact CB-CD2 4.4Å; V194-L243 HydrophobicContact CG1-CD2 3.58Å; V194-L243 HydrophobicContact CG2-CD2 4.02Å
195W98.4Very high97.4Very high2 Ų246.8 Ų46.81%0.00823%0.231CC..EExtended strand (participates in β ladder)trans-132.6160.2175.9-57.8-107000111.4I141 L164 S165 N167 I183 S185 R193 A201I141-W195 HydrophobicContact CD1-CE3 4.49Å; I141-W195 HydrophobicContact CD1-CH2 3.93Å; I141-W195 HydrophobicContact CD1-CZ3 3.88Å; L164-W195 HydrophobicContact CB-CD2 4.45Å; L164-W195 HydrophobicContact CB-CG 4.44Å; L164-W195 HydrophobicContact CD1-CB 4.11Å; L164-W195 HydrophobicContact CD1-CD2 4.33Å; L164-W195 HydrophobicContact CD1-CG 4.16Å; L164-W195 HydrophobicContact CD2-CB 4.45Å; L164-W195 HydrophobicContact CD2-CG 4.5Å; S165-W195 PolarHBondContact O-NE1 3.39Å; S165-W195 VanDerWaalsContact O-NE1 3.11Å; N167-W195 WeakPolarHBondContact ND2-CH2 3.36Å; I183-W195 HydrophobicContact CG2-CB 3.78Å; I183-W195 HydrophobicContact CG2-CE3 4.4Å; I183-W195 PolarHBondContact N-O 3.01Å; I183-W195 PolarHBondContact O-N 2.78Å; S185-W195 VanDerWaalsContact OG-CH2 3.28Å; S185-W195 WeakPolarHBondContact OG-CH2 3.41Å; S185-W195 VanDerWaalsContact OG-CZ3 3.24Å; S185-W195 WeakPolarHBondContact OG-CZ3 3.4Å; R193-W195 HydrophobicContact CB-CE3 4.3Å; R193-W195 HydrophobicContact CB-CH2 3.11Å; R193-W195 HydrophobicContact CB-CZ2 3.78Å; R193-W195 HydrophobicContact CB-CZ3 3.42Å; R193-W195 VanDerWaalsContact CB-CZ3 3.42Å; R193-W195 HydrophobicContact CG-CH2 4.14Å; R193-W195 WeakPolarHBondContact O-CZ3 3.25Å; W195-A201 CarbonylContact C-O 3.59Å; W195-A201 WeakPolarHBondContact CA-O 3.43Å; W195-A201 WeakPolarHBondContact CB-O 3.31Å
196D96.3Very high97.3Very high31 Ų3146.9 Ų46.917%0.16623%0.231CC..EExtended strand (participates in β ladder)trans-88.9116.4158.7170.84.7000108.2R198 T199 C200 A201 L203D196-R198 PolarHBondContact O-N 3.11Å; D196-R198 VanDerWaalsContact OD1-CB 3.29Å; D196-R198 WeakPolarHBondContact OD1-CB 3.25Å; D196-R198 PolarHBondContact OD1-N 3.13Å; D196-T199 WeakPolarHBondContact CB-OG1 3.4Å; D196-T199 VanDerWaalsContact CG-OG1 3.26Å; D196-T199 WeakPolarHBondContact OD2-CG2 3.17Å; D196-T199 PolarHBondContact OD2-OG1 2.92Å; D196-C200 VanDerWaalsContact O-CA 3.22Å; D196-C200 WeakPolarHBondContact O-CA 3.46Å; D196-C200 PolarHBondContact O-N 3.02Å; D196-A201 PolarHBondContact N-O 2.84Å; D196-L203 HydrophobicContact CB-CD1 4.25Å; D196-L203 HydrophobicContact CB-CD2 4.21Å; D196-L203 HydrophobicContact CB-CG 4.39Å
197P95.2Very high97.3Very high8 Ų854.4 Ų54.45%0.05226%0.264CS..THydrogen-bonded Turntrans-69.7-16.1-177.430.8-35.8000113.4L131 L143 M176 G180 T181 I183L131-P197 HydrophobicContact CD2-CB 4.18Å; L143-P197 HydrophobicContact CD1-CB 3.83Å; L143-P197 VanDerWaalsContact CD1-O 3.26Å; L143-P197 WeakPolarHBondContact CD1-O 3.39Å; L143-P197 HydrophobicContact CD2-CB 4.3Å; M176-P197 HydrophobicContact CE-CB 4.46Å; M176-P197 HydrophobicContact SD-CG 4.4Å; G180-P197 VanDerWaalsContact O-CG 3.23Å; G180-P197 WeakPolarHBondContact O-CG 3.45Å; T181-P197 WeakPolarHBondContact O-CD 3.45Å; I183-P197 HydrophobicContact CG2-CB 4.25Å
198R94.2Very high97.3Very high185 Ų18555.7 Ų55.770%0.69828%0.277SS*.THydrogen-bonded Turntrans-79.1-39.6179.7-62.7159.154136.9-1.1112D196D196-R198 PolarHBondContact O-N 3.11Å; D196-R198 VanDerWaalsContact OD1-CB 3.29Å; D196-R198 WeakPolarHBondContact OD1-CB 3.25Å; D196-R198 PolarHBondContact OD1-N 3.13Å
199T95.8Very high97.3Very high90 Ų9054.3 Ų54.355%0.55227%0.268SS*.THydrogen-bonded Turntrans-102.4-10-177.957.30000112.6D196 A201D196-T199 WeakPolarHBondContact CB-OG1 3.4Å; D196-T199 VanDerWaalsContact CG-OG1 3.26Å; D196-T199 WeakPolarHBondContact OD2-CG2 3.17Å; D196-T199 PolarHBondContact OD2-OG1 2.92Å; T199-A201 PolarHBondContact O-N 2.69Å; T199-A201 VanDerWaalsContact O-N 3.13Å; T199-A201 VanDerWaalsContact OG1-CB 3.3Å; T199-A201 WeakPolarHBondContact OG1-CB 3.47Å; T199-A201 PolarHBondContact OG1-N 2.78Å
200C96.4Very high97.3Very high46 Ų4656.7 Ų56.731%0.31129%0.286SS..THydrogen-bonded Turntrans57.715.8-168.9-58.20000113.6S162 L164 D196S162-C200 PolarHBondContact OG-SG 2.92Å; S162-C200 VanDerWaalsContact OG-SG 3.32Å; L164-C200 HydrophobicContact CD2-CB 3.61Å; D196-C200 VanDerWaalsContact O-CA 3.22Å; D196-C200 WeakPolarHBondContact O-CA 3.46Å; D196-C200 PolarHBondContact O-N 3.02Å
201A96.6Very high97.3Very high43 Ų4355.7 Ų55.736%0.35529%0.285SS..EExtended strand (participates in β ladder)trans-74.6138-177.500000111.1W195 D196 T199 L203W195-A201 CarbonylContact C-O 3.59Å; W195-A201 WeakPolarHBondContact CA-O 3.43Å; W195-A201 WeakPolarHBondContact CB-O 3.31Å; D196-A201 PolarHBondContact N-O 2.84Å; T199-A201 PolarHBondContact O-N 2.69Å; T199-A201 VanDerWaalsContact O-N 3.13Å; T199-A201 VanDerWaalsContact OG1-CB 3.3Å; T199-A201 WeakPolarHBondContact OG1-CB 3.47Å; T199-A201 PolarHBondContact OG1-N 2.78Å; A201-L203 PolarHBondContact O-N 3.02Å
202K97.6Very high97.4Very high129 Ų12955.4 Ų55.456%0.56128%0.282SS*.EExtended strand (participates in β ladder)trans-73122.1171.7-69.8164.4-176.6165.20108.6S165S165-K202 WeakPolarHBondContact O-CE 3.43Å
203L95.6Very high97.4Very high80 Ų8055.4 Ų55.442%0.41928%0.282SS..EExtended strand (participates in β ladder)trans-92-56.6179.6-59.7-178.7000111.4V194 D196 A201V194-L203 HydrophobicContact CB-CB 4.35Å; V194-L203 HydrophobicContact CG1-CB 4.24Å; V194-L203 HydrophobicContact CG1-CD1 4.11Å; V194-L203 PolarHBondContact O-N 3.35Å; D196-L203 HydrophobicContact CB-CD1 4.25Å; D196-L203 HydrophobicContact CB-CD2 4.21Å; D196-L203 HydrophobicContact CB-CG 4.39Å; A201-L203 PolarHBondContact O-N 3.02Å
204M96.6Very high97.4Very high29 Ų2957.7 Ų57.714%0.14329%0.293CS..EExtended strand (participates in β ladder)trans-159.1172-174.564.6-16675.100113.2V194 L206 L243 Q246V194-M204 HydrophobicContact CB-CG 3.71Å; V194-M204 HydrophobicContact CG1-CG 4.4Å; V194-M204 HydrophobicContact CG2-CG 3.51Å; V194-M204 HydrophobicContact CG2-SD 4.33Å; V194-M204 PolarHBondContact N-O 3.34Å; V194-M204 VanDerWaalsContact N-O 3.09Å; M204-L206 HydrophobicContact CG-CD2 4.2Å; M204-L206 HydrophobicContact CG-CG 4.38Å; M204-L206 HydrophobicContact SD-CD2 3.89Å; M204-L206 HydrophobicContact SD-CG 4.46Å; M204-L243 HydrophobicContact CE-CB 4.23Å; M204-L243 HydrophobicContact CE-CD2 4.25Å; M204-L243 WeakPolarHBondContact CE-O 3.35Å; M204-L243 HydrophobicContact SD-CB 4.17Å; M204-L243 HydrophobicContact SD-CD2 3.97Å; M204-L243 HydrophobicContact SD-CG 4.33Å; M204-Q246 HydrophobicContact CB-CG 4.47Å; M204-Q246 HydrophobicContact CE-CG 3.98Å; M204-Q246 HydrophobicContact SD-CB 4.13Å; M204-Q246 HydrophobicContact SD-CG 3.75Å
205K97.8Very high97.4Very high128 Ų12858.3 Ų58.356%0.55730%0.297SS*.EExtended strand (participates in β ladder)trans-129.3118.4172.3-67.8179.6-63.6-173.70108.8V191 L192 R193V191-K205 HydrophobicContact CG1-CB 3.87Å; V191-K205 HydrophobicContact CG1-CG 4.48Å; L192-K205 CarbonylContact O-C 3.52Å; L192-K205 WeakPolarHBondContact O-CA 3.37Å; R193-K205 HydrophobicContact CG-CG 4.38Å
206L98Very high97.4Very high2 Ų258.8 Ų58.81%0.0130%0.3CS..EExtended strand (participates in β ladder)trans-100.1109.6-179.4-51.2171.2000109.4L192 V194 M204 W241 Q246L192-L206 HydrophobicContact CB-CB 4.13Å; L192-L206 HydrophobicContact CB-CD1 4.48Å; L192-L206 HydrophobicContact CD2-CD1 4.47Å; L192-L206 PolarHBondContact N-O 3.45Å; L192-L206 PolarHBondContact O-N 3.43Å; V194-L206 HydrophobicContact CG2-CD1 4.31Å; V194-L206 HydrophobicContact CG2-CG 4.46Å; M204-L206 HydrophobicContact CG-CD2 4.2Å; M204-L206 HydrophobicContact CG-CG 4.38Å; M204-L206 HydrophobicContact SD-CD2 3.89Å; M204-L206 HydrophobicContact SD-CG 4.46Å; L206-W241 HydrophobicContact CB-CD2 4.22Å; L206-W241 HydrophobicContact CB-CE3 3.64Å; L206-W241 HydrophobicContact CB-CH2 4.25Å; L206-W241 HydrophobicContact CB-CZ3 3.66Å; L206-W241 HydrophobicContact CD1-CB 3.99Å; L206-W241 HydrophobicContact CD1-CD2 4.05Å; L206-W241 HydrophobicContact CD1-CE3 4.03Å; L206-W241 HydrophobicContact CD1-CG 4.03Å; L206-W241 HydrophobicContact CD2-CE3 4.34Å; L206-W241 HydrophobicContact CG-CE3 4.23Å; L206-Q246 HydrophobicContact CD2-CB 4.41Å
207K98.2Very high97.5Very high158 Ų15858.8 Ų58.869%0.68730%0.299SS*.EExtended strand (participates in β ladder)trans-94.8139.5177.5-62.8-174.3176.5-179.30110V191 W241V191-K207 HydrophobicContact CG1-CG 4.14Å; V191-K207 HydrophobicContact CG2-CG 3.9Å; K207-W241 WeakPolarHBondContact O-CZ3 3.43Å
208G97.7Very high97.5Very high27 Ų2759.5 Ų59.528%0.27830%0.303SS..  trans169-36.9170.900000114R239G208-R239 PolarHBondContact O-NH2 2.93Å
209H98.7Very high97.4Very high11 Ų1151.7 Ų51.75%0.05128%0.275CS..  trans-64.6151.8173.1-79.9-61.9000111.9V213 S231 S233 D235 T237 R239 W241H209-V213 HydrophobicContact CB-CG2 4.09Å; H209-S231 PolarHBondContact CD2-OG 2.82Å; H209-S231 PolarHBondContact NE2-OG 3.12Å; H209-S233 WeakPolarHBondContact CE1-CB 3.5Å; H209-S233 WeakPolarHBondContact ND1-CB 3.05Å; H209-D235 WeakPolarHBondContact CA-OD2 3.48Å; H209-D235 IonicContact CE1-OD1 3.4Å; H209-D235 IonicContact CG-OD2 3.18Å; H209-D235 IonicContact ND1-OD1 3.89Å; H209-D235 PolarHBondContact ND1-OD1 2.88Å; H209-D235 IonicContact ND1-OD2 2.98Å; H209-D235 PolarHBondContact ND1-OD2 3.25Å; H209-T237 PolarHBondContact CE1-OG1 3.17Å; H209-T237 VanDerWaalsContact CE1-OG1 3.27Å; H209-T237 PolarHBondContact ND1-OG1 3.37Å; H209-R239 VanDerWaalsContact CE1-CD 3.48Å; H209-R239 WeakPolarHBondContact CE1-CD 3.42Å; H209-W241 AromaticContact CD2-CZ2 3.99Å
210T98.6Very high96.7Very high92 Ų9254.8 Ų54.856%0.56428%0.276SS*.SBendtrans-109.7-4.1-177.859.30000113.2K190 D235K190-T210 VanDerWaalsContact CD-O 3.25Å; K190-T210 WeakPolarHBondContact CD-O 3.42Å; K190-T210 VanDerWaalsContact CE-O 3.24Å; K190-T210 WeakPolarHBondContact CE-O 3.16Å; K190-T210 PolarHBondContact NZ-O 3.19Å; T210-D235 PolarHBondContact N-OD2 3.16Å; T210-D235 WeakPolarHBondContact OG1-CB 3.43Å; T210-D235 PolarHBondContact OG1-OD2 2.93Å
211D98.7Very high95.4Very high70 Ų7054.7 Ų54.737%0.37427%0.273SS..SBendtrans-148.6-179.6177-155-5.8000111.8S233 S234 D235D211-S233 PolarHBondContact O-OG 3.21Å; D211-S234 WeakPolarHBondContact OD2-CB 3.38Å; D211-D235 HydrophobicContact CB-CB 3.88Å
212N98.7Very high92.9Very high11 Ų1155.4 Ų55.46%0.05928%0.284CS..  trans-55.9130.7-176-173.316.4000113.3Y172 S187 T188 S233 S234Y172-N212 VanDerWaalsContact CD2-ND2 3.27Å; Y172-N212 WeakPolarHBondContact CD2-ND2 3.46Å; Y172-N212 WeakPolarHBondContact CD2-OD1 3.26Å; Y172-N212 VanDerWaalsContact CG-ND2 3.28Å; S187-N212 PolarHBondContact O-OD1 2.95Å; T188-N212 HydrophobicContact CG2-CB 3.97Å; T188-N212 PolarHBondContact N-OD1 2.84Å; N212-S233 WeakPolarHBondContact O-CA 3.24Å; N212-S233 PolarHBondContact O-OG 2.86Å; N212-S233 VanDerWaalsContact O-OG 3.12Å; N212-S234 PolarHBondContact O-N 2.77Å; N212-S234 PolarHBondContact O-OG 3.46Å; N212-S234 VanDerWaalsContact O-OG 3.08Å
213V98.8Very high90.2Very high0 Ų056.3 Ų56.30%030%0.301CS..EExtended strand (participates in β ladder)trans-94114-179-176.70000110.2S173 G186 S187 L192 H209 L216S173-V213 PolarHBondContact OG-O 3.06Å; G186-V213 CarbonylContact C-O 3.59Å; S187-V213 PolarHBondContact O-N 2.8Å; L192-V213 HydrophobicContact CD1-CG1 4.37Å; L192-V213 HydrophobicContact CD1-CG2 3.9Å; H209-V213 HydrophobicContact CB-CG2 4.09Å; V213-L216 HydrophobicContact CG1-CD2 4.02Å; V213-L216 HydrophobicContact CG1-CG 4.21Å
214K98.6Very high87.8Confident69 Ų6961.1 Ų61.130%0.332%0.321SS..EExtended strand (participates in β ladder)trans-108.8-11.3-172.8-69.8-166.8-174.5175.10114.7S173 G232 W260S173-K214 VanDerWaalsContact CB-C 3.48Å; S173-K214 WeakPolarHBondContact CB-O 3.44Å; K214-G232 PolarHBondContact N-O 3.24Å; K214-W260 HydrophobicContact CD-CB 4.47Å; K214-W260 HydrophobicContact CD-CG 3.97Å
215S98.6Very high85.7Confident13 Ų1363.9 Ų63.99%0.09136%0.357CS..EExtended strand (participates in β ladder)trans-138.2137.5175.7-162.70000111.4S231 G232 L262S215-S231 CarbonylContact O-C 3.56Å; S215-S231 VanDerWaalsContact O-CA 3.31Å; S215-S231 WeakPolarHBondContact O-CA 3.32Å; S215-G232 PolarHBondContact N-O 2.97Å; S215-G232 PolarHBondContact O-N 3.26Å; S215-L262 WeakPolarHBondContact OG-CB 3.49Å; S215-L262 PolarHBondContact OG-N 2.69Å
216L98.8Very high84.4Confident12 Ų1259.5 Ų59.56%0.06334%0.343CS..EExtended strand (participates in β ladder)trans-138.5138.4178.3-72.6172.1000109.3S173 A175 V184 G186 L192 V213 L230S173-L216 WeakPolarHBondContact OG-CD1 3.03Å; A175-L216 HydrophobicContact CB-CB 3.58Å; V184-L216 HydrophobicContact CB-CD1 4.31Å; V184-L216 HydrophobicContact CG1-CD1 3.92Å; V184-L216 HydrophobicContact CG1-CD2 4.2Å; G186-L216 VanDerWaalsContact N-CD1 3.34Å; L192-L216 HydrophobicContact CD2-CD2 3.61Å; L192-L216 HydrophobicContact CG-CD2 4.04Å; V213-L216 HydrophobicContact CG1-CD2 4.02Å; V213-L216 HydrophobicContact CG1-CG 4.21Å; L216-L230 CarbonylContact C-O 3.58Å; L216-L230 WeakPolarHBondContact CA-O 3.15Å
217L98.2Very high83.7Confident31 Ų3160.7 Ų60.716%0.16235%0.35CS..EExtended strand (participates in β ladder)trans-135.3147170.9-60171.3000109.1C229 L230 L262 V264L217-C229 CarbonylContact O-C 3.47Å; L217-C229 VanDerWaalsContact O-CA 3.31Å; L217-C229 WeakPolarHBondContact O-CA 2.96Å; L217-C229 PolarHBondContact O-SG 3.35Å; L217-C229 VanDerWaalsContact O-SG 3.37Å; L217-L230 HydrophobicContact CB-CB 4.31Å; L217-L230 PolarHBondContact N-O 2.81Å; L217-L230 PolarHBondContact O-N 3.22Å; L217-L262 HydrophobicContact CD1-CB 3.65Å; L217-L262 HydrophobicContact CG-CB 4.17Å; L217-V264 HydrophobicContact CD1-CB 3.97Å; L217-V264 HydrophobicContact CD1-CG1 4.02Å
218L95.8Very high83.5Confident23 Ų2355.6 Ų55.612%0.1233%0.329CS..EExtended strand (participates in β ladder)trans-121143.8173.8-74.5164.8000108.8A175 N177 V182 V184 T227 C229 L243A175-L218 HydrophobicContact CB-CD1 4.26Å; A175-L218 HydrophobicContact CB-CG 4.38Å; N177-L218 HydrophobicContact CB-CB 4.06Å; N177-L218 HydrophobicContact CB-CD1 4.22Å; V182-L218 HydrophobicContact CG1-CD1 4.28Å; V182-L218 HydrophobicContact CG1-CD2 4.49Å; V184-L218 HydrophobicContact CG2-CD1 4.05Å; V184-L218 HydrophobicContact CG2-CD2 3.98Å; V184-L218 HydrophobicContact CG2-CG 4.39Å; L218-T227 HydrophobicContact CD2-CG2 4.42Å; L218-C229 HydrophobicContact CD2-CB 3.73Å; L218-L243 HydrophobicContact CD2-CD1 3.95Å
219N91.3Very high83.5Confident21 Ų2154.3 Ų54.311%0.11232%0.315CS..  trans-72.1160.8172.667.6-16000111.3S226 T227 Q228 F268N219-S226 PolarHBondContact ND2-O 2.79Å; N219-T227 WeakPolarHBondContact OD1-CA 3.48Å; N219-Q228 PolarHBondContact N-O 2.8Å; N219-Q228 VanDerWaalsContact N-O 3.14Å; N219-Q228 PolarHBondContact ND2-N 2.81Å; N219-Q228 PolarHBondContact OD1-N 3.49Å; N219-Q228 PolarHBondContact OD1-O 3.17Å; N219-F268 HydrophobicContact CB-CB 4.19Å; N219-F268 HydrophobicContact CB-CD1 3.92Å; N219-F268 HydrophobicContact CB-CD2 3.55Å; N219-F268 HydrophobicContact CB-CE1 4.12Å; N219-F268 HydrophobicContact CB-CE2 3.77Å; N219-F268 HydrophobicContact CB-CG 3.63Å; N219-F268 HydrophobicContact CB-CZ 4.04Å
220R82.1Confident83.5Confident155 Ų15553.8 Ų53.859%0.58531%0.313SS*.  trans-74.6123.1164.3-168.9178.7-176.3-179.3-1.3107.1Q178 G222Q178-R220 HydrophobicContact CB-CG 4.36Å; R220-G222 PolarHBondContact O-N 3.08Å
221D68.4Low83.5Confident45 Ų4549.4 Ų49.424%0.24129%0.286CS..SBendtrans-63.8103.7176.6-71-48.9000109.2N177 M179 T227N177-D221 PolarHBondContact ND2-OD2 3.26Å; M179-D221 HydrophobicContact SD-CB 3.91Å; D221-T227 WeakPolarHBondContact OD1-CA 3.39Å; D221-T227 VanDerWaalsContact OD1-CB 3.24Å; D221-T227 WeakPolarHBondContact OD1-CB 3.15Å; D221-T227 WeakPolarHBondContact OD1-CG2 3.45Å; D221-T227 PolarHBondContact OD1-OG1 2.82Å
222G45.4Very low83.5Confident57 Ų5746 Ų4659%0.58827%0.268SS*.  trans17381.6-179.300000114.8R220R220-G222 PolarHBondContact O-N 3.08Å
223T39.6Very low83.5Confident148 Ų14845.5 Ų45.591%0.90827%0.265SS*.SBendtrans166.1-14.413632.40000113.3
224Q45.6Very low83.5Confident181 Ų18146.8 Ų46.885%0.84627%0.274SS*.SBendtrans-133.319.4-177.6-73-101.3-10.500114.1S226Q224-S226 PolarHBondContact O-N 3.17Å
225G51.8Low83.5Confident88 Ų8845.1 Ų45.191%0.90727%0.269SS*.SBendtrans63.56.5171.300000117.3
226S70.6Confident83.5Confident36 Ų3644.9 Ų44.925%0.25227%0.268SS..  trans-120.9110.7178.9-158.80000111N219 Q224 Q228 S242N219-S226 PolarHBondContact ND2-O 2.79Å; Q224-S226 PolarHBondContact O-N 3.17Å; S226-Q228 PolarHBondContact O-N 2.83Å; S226-S242 PolarHBondContact OG-OG 3.41Å
227T84.6Confident83.5Confident26 Ų2644.8 Ų44.816%0.1627%0.268CS..  trans-62.5128.4165.5-41.60000108.1V182 L218 N219 D221 L243V182-T227 HydrophobicContact CG2-CG2 4.36Å; L218-T227 HydrophobicContact CD2-CG2 4.42Å; N219-T227 WeakPolarHBondContact OD1-CA 3.48Å; D221-T227 WeakPolarHBondContact OD1-CA 3.39Å; D221-T227 VanDerWaalsContact OD1-CB 3.24Å; D221-T227 WeakPolarHBondContact OD1-CB 3.15Å; D221-T227 WeakPolarHBondContact OD1-CG2 3.45Å; D221-T227 PolarHBondContact OD1-OG1 2.82Å; T227-L243 HydrophobicContact CG2-CD1 3.68Å; T227-L243 WeakPolarHBondContact O-CB 2.97Å; T227-L243 VanDerWaalsContact O-CD1 3.28Å; T227-L243 WeakPolarHBondContact O-CD1 3.34Å; T227-L243 PolarHBondContact O-N 2.91Å
228Q93.7Very high83.5Confident51 Ų5143.3 Ų43.324%0.23826%0.26CS..EExtended strand (participates in β ladder)trans-119.7148.8179.7-68.5-178.5-29.500110.3N219 S226 L240 W241 F268N219-Q228 PolarHBondContact N-O 2.8Å; N219-Q228 VanDerWaalsContact N-O 3.14Å; N219-Q228 PolarHBondContact ND2-N 2.81Å; N219-Q228 PolarHBondContact OD1-N 3.49Å; N219-Q228 PolarHBondContact OD1-O 3.17Å; S226-Q228 PolarHBondContact O-N 2.83Å; Q228-L240 HydrophobicContact CB-CD1 4.21Å; Q228-W241 VanDerWaalsContact CA-O 3.23Å; Q228-W241 WeakPolarHBondContact CA-O 3.38Å; Q228-F268 HydrophobicContact CB-CD1 4.44Å; Q228-F268 HydrophobicContact CB-CE1 3.78Å; Q228-F268 HydrophobicContact CB-CZ 4.42Å
229C97.1Very high83.6Confident0 Ų043.9 Ų43.90%026%0.261CS..EExtended strand (participates in β ladder)trans-124.5138.4176-179.30000110L217 L218 L240 W241 L243L217-C229 CarbonylContact O-C 3.47Å; L217-C229 VanDerWaalsContact O-CA 3.31Å; L217-C229 WeakPolarHBondContact O-CA 2.96Å; L217-C229 PolarHBondContact O-SG 3.35Å; L217-C229 VanDerWaalsContact O-SG 3.37Å; L218-C229 HydrophobicContact CD2-CB 3.73Å; C229-L240 CarbonylContact O-C 3.44Å; C229-L240 WeakPolarHBondContact O-CA 3.18Å; C229-W241 HydrophobicContact CB-CB 4.19Å; C229-W241 PolarHBondContact N-O 2.89Å; C229-W241 PolarHBondContact O-N 3.18Å; C229-L243 HydrophobicContact CB-CD1 4.03Å
230L98.5Very high84Confident0 Ų043.4 Ų43.40%026%0.258CS..EExtended strand (participates in β ladder)trans-105137.7164.4-75.6165.1000109.2L216 L217 I238 R239 L240 L262 V264 F268 V271 L285L216-L230 CarbonylContact C-O 3.58Å; L216-L230 WeakPolarHBondContact CA-O 3.15Å; L217-L230 HydrophobicContact CB-CB 4.31Å; L217-L230 PolarHBondContact N-O 2.81Å; L217-L230 PolarHBondContact O-N 3.22Å; L230-I238 HydrophobicContact CD2-CG2 4.32Å; L230-R239 CarbonylContact C-O 3.37Å; L230-R239 VanDerWaalsContact CA-O 3.32Å; L230-R239 WeakPolarHBondContact CA-O 3.43Å; L230-L240 HydrophobicContact CD2-CB 4.04Å; L230-L240 HydrophobicContact CD2-CD1 3.81Å; L230-L240 HydrophobicContact CD2-CG 4.5Å; L230-L240 HydrophobicContact CG-CD1 4.08Å; L230-L262 HydrophobicContact CB-CD1 4.37Å; L230-V264 HydrophobicContact CD1-CB 4.34Å; L230-V264 HydrophobicContact CD1-CG2 4.01Å; L230-F268 HydrophobicContact CB-CZ 4.31Å; L230-F268 HydrophobicContact CD1-CE1 4.05Å; L230-F268 HydrophobicContact CD1-CE2 3.96Å; L230-F268 HydrophobicContact CD1-CZ 3.61Å; L230-F268 HydrophobicContact CG-CE1 4.04Å; L230-F268 HydrophobicContact CG-CE2 4.42Å; L230-F268 HydrophobicContact CG-CZ 3.64Å; L230-V271 HydrophobicContact CD1-CB 4.15Å; L230-V271 HydrophobicContact CD1-CG2 4.04Å; L230-L285 HydrophobicContact CD1-CD1 3.99Å; L230-L285 HydrophobicContact CD2-CD1 4.31Å; L230-L285 HydrophobicContact CD2-CD2 3.78Å
231S98.8Very high84.7Confident0 Ų036.1 Ų36.10%023%0.231CC..EExtended strand (participates in β ladder)trans-134.3137.3176.363.80000112.5H209 S215 I238 R239 W241H209-S231 PolarHBondContact CD2-OG 2.82Å; H209-S231 PolarHBondContact NE2-OG 3.12Å; S215-S231 CarbonylContact O-C 3.56Å; S215-S231 VanDerWaalsContact O-CA 3.31Å; S215-S231 WeakPolarHBondContact O-CA 3.32Å; S231-I238 CarbonylContact O-C 3.59Å; S231-I238 VanDerWaalsContact O-CA 3.26Å; S231-I238 WeakPolarHBondContact O-CA 3.45Å; S231-R239 PolarHBondContact N-O 3.5Å; S231-R239 PolarHBondContact O-N 2.84Å; S231-W241 PolarHBondContact OG-NE1 2.78Å
232G98.8Very high86Confident0 Ų034 Ų340%022%0.22CC..EExtended strand (participates in β ladder)trans-113.6129.8175.500000110K214 S215 V259 L262K214-G232 PolarHBondContact N-O 3.24Å; S215-G232 PolarHBondContact N-O 2.97Å; S215-G232 PolarHBondContact O-N 3.26Å; G232-V259 CarbonylContact C-O 3.59Å; G232-L262 VanDerWaalsContact N-CD1 3.34Å
233S98.9Very high88.3Confident0 Ų031.7 Ų31.70%019%0.194CC..EExtended strand (participates in β ladder)trans-125158.5-174.3175.60000112.8H209 D211 N212 D235 G236 T237 V259H209-S233 WeakPolarHBondContact CE1-CB 3.5Å; H209-S233 WeakPolarHBondContact ND1-CB 3.05Å; D211-S233 PolarHBondContact O-OG 3.21Å; N212-S233 WeakPolarHBondContact O-CA 3.24Å; N212-S233 PolarHBondContact O-OG 2.86Å; N212-S233 VanDerWaalsContact O-OG 3.12Å; S233-D235 VanDerWaalsContact CB-OD1 3.29Å; S233-D235 WeakPolarHBondContact CB-OD1 3.49Å; S233-D235 PolarHBondContact O-N 3.46Å; S233-D235 VanDerWaalsContact O-N 3.17Å; S233-D235 PolarHBondContact OG-N 2.95Å; S233-D235 PolarHBondContact OG-OD1 3.21Å; S233-G236 PolarHBondContact O-N 3.46Å; S233-G236 VanDerWaalsContact O-N 3.16Å; S233-T237 PolarHBondContact N-O 3.36Å; S233-V259 CarbonylContact C-O 3.53Å; S233-V259 PolarHBondContact O-N 3.14Å
234S98.8Very high90.8Very high26 Ų2627.7 Ų27.718%0.18218%0.182CC..THydrogen-bonded Turntrans-63.6-12.4172.2-53.30000112.7D211 N212 G236 G258D211-S234 WeakPolarHBondContact OD2-CB 3.38Å; N212-S234 PolarHBondContact O-N 2.77Å; N212-S234 PolarHBondContact O-OG 3.46Å; N212-S234 VanDerWaalsContact O-OG 3.08Å; S234-G236 PolarHBondContact O-N 2.6Å; S234-G258 WeakPolarHBondContact O-CA 3.42Å
235D98.6Very high93Very high35 Ų3524.3 Ų24.319%0.18717%0.166CC..THydrogen-bonded Turntrans-74.84.2171.468.517.1000114.7H209 T210 D211 S233 T237H209-D235 WeakPolarHBondContact CA-OD2 3.48Å; H209-D235 IonicContact CE1-OD1 3.4Å; H209-D235 IonicContact CG-OD2 3.18Å; H209-D235 IonicContact ND1-OD1 3.89Å; H209-D235 PolarHBondContact ND1-OD1 2.88Å; H209-D235 IonicContact ND1-OD2 2.98Å; H209-D235 PolarHBondContact ND1-OD2 3.25Å; T210-D235 PolarHBondContact N-OD2 3.16Å; T210-D235 WeakPolarHBondContact OG1-CB 3.43Å; T210-D235 PolarHBondContact OG1-OD2 2.93Å; D211-D235 HydrophobicContact CB-CB 3.88Å; S233-D235 VanDerWaalsContact CB-OD1 3.29Å; S233-D235 WeakPolarHBondContact CB-OD1 3.49Å; S233-D235 PolarHBondContact O-N 3.46Å; S233-D235 VanDerWaalsContact O-N 3.17Å; S233-D235 PolarHBondContact OG-N 2.95Å; S233-D235 PolarHBondContact OG-OD1 3.21Å; D235-T237 PolarHBondContact O-N 2.56Å; D235-T237 VanDerWaalsContact OD1-CB 3.31Å; D235-T237 WeakPolarHBondContact OD1-CB 3.4Å; D235-T237 PolarHBondContact OD1-N 2.83Å; D235-T237 PolarHBondContact OD1-OG1 2.96Å; D235-T237 PolarHBondContact OD2-OG1 3.26Å
236G98Very high95.1Very high8 Ų825.7 Ų25.78%0.08215%0.149CC..SBendtrans78.92.4179.100000114.4S233 S234 E257S233-G236 PolarHBondContact O-N 3.46Å; S233-G236 VanDerWaalsContact O-N 3.16Å; S234-G236 PolarHBondContact O-N 2.6Å; G236-E257 VanDerWaalsContact CA-O 3.32Å; G236-E257 WeakPolarHBondContact CA-O 3.36Å
237T98.7Very high96.4Very high9 Ų930.1 Ų30.16%0.05516%0.16CC..  trans-104.1148.1-178.174.40000113.1H209 S233 D235 T251 Y252 R253H209-T237 PolarHBondContact CE1-OG1 3.17Å; H209-T237 VanDerWaalsContact CE1-OG1 3.27Å; H209-T237 PolarHBondContact ND1-OG1 3.37Å; S233-T237 PolarHBondContact N-O 3.36Å; D235-T237 PolarHBondContact O-N 2.56Å; D235-T237 VanDerWaalsContact OD1-CB 3.31Å; D235-T237 WeakPolarHBondContact OD1-CB 3.4Å; D235-T237 PolarHBondContact OD1-N 2.83Å; D235-T237 PolarHBondContact OD1-OG1 2.96Å; D235-T237 PolarHBondContact OD2-OG1 3.26Å; T237-T251 HydrophobicContact CG2-CG2 4.12Å; T237-Y252 WeakPolarHBondContact CA-O 3.36Å; T237-R253 HydrophobicContact CG2-CG 4.08Å
238I98.9Very high97Very high1 Ų130.3 Ų30.31%0.00516%0.162CC..EExtended strand (participates in β ladder)trans-106.7132.4164.4-52.9166000107.1L230 S231 T251 Y252 V254 V259 L262 S273L230-I238 HydrophobicContact CD2-CG2 4.32Å; S231-I238 CarbonylContact O-C 3.59Å; S231-I238 VanDerWaalsContact O-CA 3.26Å; S231-I238 WeakPolarHBondContact O-CA 3.45Å; I238-T251 CarbonylContact O-C 3.58Å; I238-T251 WeakPolarHBondContact O-CA 3.46Å; I238-Y252 HydrophobicContact CB-CD2 4.06Å; I238-Y252 HydrophobicContact CG2-CD2 4.05Å; I238-Y252 PolarHBondContact N-O 3.22Å; I238-Y252 WeakPolarHBondContact O-CD2 3.14Å; I238-Y252 PolarHBondContact O-N 3.39Å; I238-V254 HydrophobicContact CD1-CG2 3.97Å; I238-V259 HydrophobicContact CG1-CG1 4.14Å; I238-V259 HydrophobicContact CG1-CG2 4.19Å; I238-L262 HydrophobicContact CD1-CD2 4.06Å; I238-L262 HydrophobicContact CG1-CD2 4.14Å; I238-L262 HydrophobicContact CG2-CD1 4.26Å; I238-L262 HydrophobicContact CG2-CD2 4.26Å; I238-S273 WeakPolarHBondContact CD1-OG 3.39Å
239R98.7Very high97.1Very high34 Ų3430.7 Ų30.713%0.12817%0.165CC..EExtended strand (participates in β ladder)trans-121.5137.4179.4-69.3-178.7179.7-114.71.2111.5G208 H209 L230 S231 W241 A250 T251G208-R239 PolarHBondContact O-NH2 2.93Å; H209-R239 VanDerWaalsContact CE1-CD 3.48Å; H209-R239 WeakPolarHBondContact CE1-CD 3.42Å; L230-R239 CarbonylContact C-O 3.37Å; L230-R239 VanDerWaalsContact CA-O 3.32Å; L230-R239 WeakPolarHBondContact CA-O 3.43Å; S231-R239 PolarHBondContact N-O 3.5Å; S231-R239 PolarHBondContact O-N 2.84Å; R239-W241 HydrophobicContact CB-CZ2 3.86Å; R239-W241 VanDerWaalsContact CD-CZ2 3.44Å; R239-W241 HydrophobicContact CG-CZ2 4.3Å; R239-A250 WeakPolarHBondContact CA-O 3.5Å; R239-T251 HydrophobicContact CG-CG2 4.18Å
240L98.4Very high97.2Very high12 Ų1232 Ų326%0.06318%0.176CC..EExtended strand (participates in β ladder)trans-101130.7168.6-179.565000108.8Q228 C229 L230 I249 A250 Y252 F268Q228-L240 HydrophobicContact CB-CD1 4.21Å; C229-L240 CarbonylContact O-C 3.44Å; C229-L240 WeakPolarHBondContact O-CA 3.18Å; L230-L240 HydrophobicContact CD2-CB 4.04Å; L230-L240 HydrophobicContact CD2-CD1 3.81Å; L230-L240 HydrophobicContact CD2-CG 4.5Å; L230-L240 HydrophobicContact CG-CD1 4.08Å; L240-I249 HydrophobicContact CB-CG1 4.12Å; L240-I249 HydrophobicContact CD2-CD1 3.66Å; L240-I249 HydrophobicContact CD2-CG1 3.87Å; L240-I249 HydrophobicContact CG-CD1 3.74Å; L240-I249 HydrophobicContact CG-CG1 3.66Å; L240-I249 WeakPolarHBondContact O-CG1 3.47Å; L240-I249 PolarHBondContact O-N 2.84Å; L240-A250 HydrophobicContact CB-CB 4.18Å; L240-A250 PolarHBondContact N-O 3.21Å; L240-A250 PolarHBondContact O-N 3.08Å; L240-Y252 HydrophobicContact CB-CE2 4.06Å; L240-F268 HydrophobicContact CD1-CE1 3.8Å
241W97.8Very high97.1Very high1 Ų134.1 Ų34.10%0.00419%0.189CC..EExtended strand (participates in β ladder)trans-120.5139-177.6-51.286.8000110.3L192 L206 K207 H209 Q228 C229 S231 R239 R247 C248L192-W241 HydrophobicContact CD1-CZ2 4.3Å; L206-W241 HydrophobicContact CB-CD2 4.22Å; L206-W241 HydrophobicContact CB-CE3 3.64Å; L206-W241 HydrophobicContact CB-CH2 4.25Å; L206-W241 HydrophobicContact CB-CZ3 3.66Å; L206-W241 HydrophobicContact CD1-CB 3.99Å; L206-W241 HydrophobicContact CD1-CD2 4.05Å; L206-W241 HydrophobicContact CD1-CE3 4.03Å; L206-W241 HydrophobicContact CD1-CG 4.03Å; L206-W241 HydrophobicContact CD2-CE3 4.34Å; L206-W241 HydrophobicContact CG-CE3 4.23Å; K207-W241 WeakPolarHBondContact O-CZ3 3.43Å; H209-W241 AromaticContact CD2-CZ2 3.99Å; Q228-W241 VanDerWaalsContact CA-O 3.23Å; Q228-W241 WeakPolarHBondContact CA-O 3.38Å; C229-W241 HydrophobicContact CB-CB 4.19Å; C229-W241 PolarHBondContact N-O 2.89Å; C229-W241 PolarHBondContact O-N 3.18Å; S231-W241 PolarHBondContact OG-NE1 2.78Å; R239-W241 HydrophobicContact CB-CZ2 3.86Å; R239-W241 VanDerWaalsContact CD-CZ2 3.44Å; R239-W241 HydrophobicContact CG-CZ2 4.3Å; W241-R247 WeakPolarHBondContact CA-O 3.45Å; W241-C248 HydrophobicContact CD2-CB 4.25Å; W241-C248 VanDerWaalsContact CE3-CA 3.46Å; W241-C248 HydrophobicContact CE3-CB 3.63Å; W241-C248 VanDerWaalsContact CE3-N 3.27Å; W241-C248 HydrophobicContact CH2-CB 4.03Å; W241-C248 HydrophobicContact CZ3-CB 3.5Å; W241-C248 VanDerWaalsContact CZ3-CB 3.5Å
242S95.3Very high97.1Very high1 Ų134.6 Ų34.61%0.00719%0.191CC..EExtended strand (participates in β ladder)trans-97.1118163.4173.90000108.1S226 G244 Q245 Q246 R247S226-S242 PolarHBondContact OG-OG 3.41Å; S242-G244 VanDerWaalsContact C-N 3.35Å; S242-Q245 PolarHBondContact O-N 3.39Å; S242-Q245 PolarHBondContact OG-N 3.27Å; S242-Q246 WeakPolarHBondContact O-CA 3.47Å; S242-Q246 PolarHBondContact O-N 2.85Å; S242-R247 PolarHBondContact N-O 3.21Å; S242-R247 PolarHBondContact O-N 2.96Å
243L93.6Very high97Very high9 Ų943 Ų435%0.04722%0.223CC..THydrogen-bonded Turntrans-71.6-32.4176.4-73.1114.3000111.6V182 V194 M204 L218 T227 C229 Q245 Q246V182-L243 HydrophobicContact CG1-CD2 3.95Å; V194-L243 HydrophobicContact CB-CD2 4.4Å; V194-L243 HydrophobicContact CG1-CD2 3.58Å; V194-L243 HydrophobicContact CG2-CD2 4.02Å; M204-L243 HydrophobicContact CE-CB 4.23Å; M204-L243 HydrophobicContact CE-CD2 4.25Å; M204-L243 WeakPolarHBondContact CE-O 3.35Å; M204-L243 HydrophobicContact SD-CB 4.17Å; M204-L243 HydrophobicContact SD-CD2 3.97Å; M204-L243 HydrophobicContact SD-CG 4.33Å; L218-L243 HydrophobicContact CD2-CD1 3.95Å; T227-L243 HydrophobicContact CG2-CD1 3.68Å; T227-L243 WeakPolarHBondContact O-CB 2.97Å; T227-L243 VanDerWaalsContact O-CD1 3.28Å; T227-L243 WeakPolarHBondContact O-CD1 3.34Å; T227-L243 PolarHBondContact O-N 2.91Å; C229-L243 HydrophobicContact CB-CD1 4.03Å; L243-Q245 VanDerWaalsContact C-N 3.35Å; L243-Q245 PolarHBondContact O-N 3.14Å; L243-Q246 WeakPolarHBondContact O-CG 3.44Å; L243-Q246 PolarHBondContact O-N 2.92Å
244G91.1Very high96.8Very high64 Ų6443.6 Ų43.666%0.6623%0.227SC*.THydrogen-bonded Turntrans-62.4-40.4173.800000112.9S242S242-G244 VanDerWaalsContact C-N 3.35Å
245Q93.3Very high96.7Very high110 Ų11043.1 Ų43.151%0.51422%0.221SC..THydrogen-bonded Turntrans-88.6-4.3176.6-58.9178.734.800113.4S242 L243 R247S242-Q245 PolarHBondContact O-N 3.39Å; S242-Q245 PolarHBondContact OG-N 3.27Å; L243-Q245 VanDerWaalsContact C-N 3.35Å; L243-Q245 PolarHBondContact O-N 3.14Å; Q245-R247 HydrophobicContact CB-CG 3.92Å; Q245-R247 PolarHBondContact O-N 3.38Å; Q245-R247 VanDerWaalsContact O-N 3.15Å
246Q95.8Very high96.6Very high116 Ų11648.6 Ų48.654%0.54225%0.246SC..THydrogen-bonded Turntrans50.335.9-178.1-49.3-171.112.700114.4M204 L206 S242 L243M204-Q246 HydrophobicContact CB-CG 4.47Å; M204-Q246 HydrophobicContact CE-CG 3.98Å; M204-Q246 HydrophobicContact SD-CB 4.13Å; M204-Q246 HydrophobicContact SD-CG 3.75Å; L206-Q246 HydrophobicContact CD2-CB 4.41Å; S242-Q246 WeakPolarHBondContact O-CA 3.47Å; S242-Q246 PolarHBondContact O-N 2.85Å; L243-Q246 WeakPolarHBondContact O-CG 3.44Å; L243-Q246 PolarHBondContact O-N 2.92Å
247R96.3Very high96.6Very high129 Ų12952.2 Ų52.249%0.48726%0.26SS..EExtended strand (participates in β ladder)trans-145.3161.5-17671.7179.4-175.393-3.3113.2W241 S242 Q245 I249W241-R247 WeakPolarHBondContact CA-O 3.45Å; S242-R247 PolarHBondContact N-O 3.21Å; S242-R247 PolarHBondContact O-N 2.96Å; Q245-R247 HydrophobicContact CB-CG 3.92Å; Q245-R247 PolarHBondContact O-N 3.38Å; Q245-R247 VanDerWaalsContact O-N 3.15Å; R247-I249 HydrophobicContact CG-CG2 4.29Å
248C97.9Very high96.6Very high30 Ų3052 Ų5220%0.20326%0.261CS..EExtended strand (participates in β ladder)trans-69.5131.7166.8-171.40000108.9W241 A250W241-C248 HydrophobicContact CD2-CB 4.25Å; W241-C248 VanDerWaalsContact CE3-CA 3.46Å; W241-C248 HydrophobicContact CE3-CB 3.63Å; W241-C248 VanDerWaalsContact CE3-N 3.27Å; W241-C248 HydrophobicContact CH2-CB 4.03Å; W241-C248 HydrophobicContact CZ3-CB 3.5Å; W241-C248 VanDerWaalsContact CZ3-CB 3.5Å; C248-A250 PolarHBondContact SG-O 2.88Å
249I96.8Very high96.6Very high59 Ų5952 Ų5230%0.30326%0.261SS..EExtended strand (participates in β ladder)trans-109.1-23.4178.160.5171.2000112.7L240 R247L240-I249 HydrophobicContact CB-CG1 4.12Å; L240-I249 HydrophobicContact CD2-CD1 3.66Å; L240-I249 HydrophobicContact CD2-CG1 3.87Å; L240-I249 HydrophobicContact CG-CD1 3.74Å; L240-I249 HydrophobicContact CG-CG1 3.66Å; L240-I249 WeakPolarHBondContact O-CG1 3.47Å; L240-I249 PolarHBondContact O-N 2.84Å; R247-I249 HydrophobicContact CG-CG2 4.29Å
250A97.6Very high96.6Very high28 Ų2852.5 Ų52.523%0.23126%0.262CS..EExtended strand (participates in β ladder)trans-151.6152.3172.600000111.8R239 L240 C248 Y252R239-A250 WeakPolarHBondContact CA-O 3.5Å; L240-A250 HydrophobicContact CB-CB 4.18Å; L240-A250 PolarHBondContact N-O 3.21Å; L240-A250 PolarHBondContact O-N 3.08Å; C248-A250 PolarHBondContact SG-O 2.88Å; A250-Y252 HydrophobicContact CB-CE1 4.07Å; A250-Y252 HydrophobicContact CB-CE2 4.13Å; A250-Y252 WeakPolarHBondContact CB-OH 3.44Å
251T98.3Very high96.6Very high45 Ų4552 Ų5228%0.27626%0.26SS..EExtended strand (participates in β ladder)trans-133.4120.5175.1-60.10000109.2T237 I238 R239T237-T251 HydrophobicContact CG2-CG2 4.12Å; I238-T251 CarbonylContact O-C 3.58Å; I238-T251 WeakPolarHBondContact O-CA 3.46Å; R239-T251 HydrophobicContact CG-CG2 4.18Å
252Y97.6Very high96.6Very high10 Ų1052.2 Ų52.24%0.03926%0.261CS..EExtended strand (participates in β ladder)trans-106.1132.6-178.6-43.6-77.2000109.9T237 I238 L240 A250 L285 P288T237-Y252 WeakPolarHBondContact CA-O 3.36Å; I238-Y252 HydrophobicContact CB-CD2 4.06Å; I238-Y252 HydrophobicContact CG2-CD2 4.05Å; I238-Y252 PolarHBondContact N-O 3.22Å; I238-Y252 WeakPolarHBondContact O-CD2 3.14Å; I238-Y252 PolarHBondContact O-N 3.39Å; L240-Y252 HydrophobicContact CB-CE2 4.06Å; A250-Y252 HydrophobicContact CB-CE1 4.07Å; A250-Y252 HydrophobicContact CB-CE2 4.13Å; A250-Y252 WeakPolarHBondContact CB-OH 3.44Å; Y252-L285 HydrophobicContact CD2-CD2 4.33Å; Y252-L285 HydrophobicContact CE2-CD2 3.5Å; Y252-L285 VanDerWaalsContact CE2-CD2 3.5Å; Y252-L285 PolarHBondContact OH-O 2.88Å; Y252-P288 HydrophobicContact CD1-CB 3.64Å; Y252-P288 HydrophobicContact CE1-CB 3.92Å
253R96.8Very high96.8Very high176 Ų17652.9 Ų52.966%0.66426%0.264SS*.  trans-120.874180-67.3-174.7-18080.5-2.4109.6T237T237-R253 HydrophobicContact CG2-CG 4.08Å
254V95.1Very high97Very high13 Ų1353 Ų538%0.07927%0.266CS..  trans-101-13.1-179.1-580000113I238 Y281 T283I238-V254 HydrophobicContact CD1-CG2 3.97Å; V254-Y281 HydrophobicContact CB-CD2 4.39Å; V254-Y281 HydrophobicContact CG2-CD2 4.21Å; V254-Y281 HydrophobicContact CG2-CG 4.47Å; V254-Y281 VanDerWaalsContact O-CE2 3.26Å; V254-Y281 WeakPolarHBondContact O-CE2 3.47Å; V254-T283 HydrophobicContact CG1-CG2 4.39Å
255H96.8Very high97.1Very high16 Ų1650.6 Ų50.67%0.07424%0.237CC..  trans-111.2147.9-179.5-71.2-82.5000111.3E257 V259 S273 D277 K279 Y281H255-E257 WeakPolarHBondContact CB-O 3.43Å; H255-V259 HydrophobicContact CB-CG2 3.85Å; H255-V259 VanDerWaalsContact CD2-CG2 3.46Å; H255-V259 WeakPolarHBondContact CD2-CG2 3.48Å; H255-S273 VanDerWaalsContact NE2-CB 3.31Å; H255-S273 WeakPolarHBondContact NE2-CB 3.49Å; H255-S273 PolarHBondContact NE2-O 3.07Å; H255-S273 PolarHBondContact NE2-OG 3.43Å; H255-D277 VanDerWaalsContact CA-OD2 3.31Å; H255-D277 WeakPolarHBondContact CA-OD2 3.33Å; H255-D277 VanDerWaalsContact CB-OD2 3.22Å; H255-D277 WeakPolarHBondContact CB-OD2 3.42Å; H255-D277 IonicContact CE1-OD1 2.83Å; H255-D277 IonicContact CG-OD2 2.71Å; H255-D277 VanDerWaalsContact ND1-CG 3.31Å; H255-D277 IonicContact ND1-OD1 3.25Å; H255-D277 PolarHBondContact ND1-OD1 3.01Å; H255-D277 IonicContact ND1-OD2 3.85Å; H255-D277 PolarHBondContact ND1-OD2 3.12Å; H255-K279 PolarHBondContact CE1-O 2.79Å; H255-Y281 AromaticContact CE1-CD2 3.6Å; H255-Y281 AromaticContact NE2-CD2 3.83Å
256E95.3Very high97Very high150 Ų15051 Ų5170%0.70124%0.239SC*.SBendtrans-87.7-24.9176.8-68167.6-13900111.8D277 K279E256-D277 PolarHBondContact N-OD2 3.11Å; E256-K279 IonicContact OE1-NZ 3.54Å; E256-K279 PolarHBondContact OE1-NZ 3.21Å
257E98.2Very high96.8Very high83 Ų8348.3 Ų48.339%0.38824%0.237SC..SBendtrans-126.3-178178.7-60.6-173.3-114.600111.1G236 H255 V259 R276 D277G236-E257 VanDerWaalsContact CA-O 3.32Å; G236-E257 WeakPolarHBondContact CA-O 3.36Å; H255-E257 WeakPolarHBondContact CB-O 3.43Å; E257-V259 PolarHBondContact O-N 3.26Å; E257-R276 HydrophobicContact CB-CB 3.8Å; E257-R276 HydrophobicContact CB-CG 4.27Å; E257-R276 WeakPolarHBondContact OE2-CD 3.39Å; E257-R276 WeakPolarHBondContact OE2-CG 2.98Å; E257-R276 IonicContact OE2-CZ 3.52Å; E257-R276 IonicContact OE2-NE 2.78Å; E257-R276 PolarHBondContact OE2-NE 3.12Å; E257-D277 HydrophobicContact CB-CB 4.13Å; E257-D277 HydrophobicContact CG-CB 4.33Å
258G98.4Very high96.6Very high6 Ų643.2 Ų43.26%0.06222%0.218CC..  trans-57.7134.1-175.300000115.1S234 G275 R276S234-G258 WeakPolarHBondContact O-CA 3.42Å; G258-G275 WeakPolarHBondContact O-CA 3.4Å; G258-R276 PolarHBondContact O-N 2.98Å
259V98.9Very high96.4Very high0 Ų043.2 Ų43.20%022%0.218CC..EExtended strand (participates in β ladder)trans-88.6121.6176.9-1730000110G232 S233 I238 H255 E257 L262G232-V259 CarbonylContact C-O 3.59Å; S233-V259 CarbonylContact C-O 3.53Å; S233-V259 PolarHBondContact O-N 3.14Å; I238-V259 HydrophobicContact CG1-CG1 4.14Å; I238-V259 HydrophobicContact CG1-CG2 4.19Å; H255-V259 HydrophobicContact CB-CG2 3.85Å; H255-V259 VanDerWaalsContact CD2-CG2 3.46Å; H255-V259 WeakPolarHBondContact CD2-CG2 3.48Å; E257-V259 PolarHBondContact O-N 3.26Å; V259-L262 HydrophobicContact CG1-CD2 3.9Å
260W98.8Very high96.3Very high44 Ų4441.3 Ų41.317%0.16721%0.207CC..EExtended strand (participates in β ladder)trans-116.9-23.7-170.6-60.7-12.6000113.7K214 G274 R276 P300 L302K214-W260 HydrophobicContact CD-CB 4.47Å; K214-W260 HydrophobicContact CD-CG 3.97Å; W260-G274 PolarHBondContact N-O 3.15Å; W260-R276 HydrophobicContact CD2-CB 4.48Å; W260-R276 HydrophobicContact CH2-CB 3.75Å; W260-R276 HydrophobicContact CH2-CG 3.69Å; W260-R276 HydrophobicContact CZ2-CB 3.56Å; W260-R276 HydrophobicContact CZ2-CG 3.76Å; W260-R276 HydrophobicContact CZ3-CB 4.29Å; W260-P300 HydrophobicContact CE3-CB 4.48Å; W260-P300 HydrophobicContact CH2-CB 4.33Å; W260-P300 HydrophobicContact CZ3-CB 3.67Å; W260-L302 HydrophobicContact CE3-CD2 3.92Å; W260-L302 HydrophobicContact CZ3-CD2 4.03Å
261A98.8Very high96.4Very high1 Ų140 Ų401%0.00820%0.196CC..EExtended strand (participates in β ladder)trans-131135.6-179.600000110.7S273 G274 V301 M304A261-S273 WeakPolarHBondContact O-CA 3.49Å; A261-G274 PolarHBondContact N-O 3.05Å; A261-G274 PolarHBondContact O-N 3.41Å; A261-V301 HydrophobicContact CB-CG1 4.15Å; A261-M304 HydrophobicContact CB-CE 3.95Å; A261-M304 HydrophobicContact CB-CG 4.1Å; A261-M304 WeakPolarHBondContact O-CE 3.4Å
262L98.9Very high96.4Very high6 Ų638 Ų383%0.03118%0.184CC..EExtended strand (participates in β ladder)trans-128.9146.5171.4-62.5177.9000109.7S215 L217 L230 G232 I238 V259 V271 Y272S215-L262 WeakPolarHBondContact OG-CB 3.49Å; S215-L262 PolarHBondContact OG-N 2.69Å; L217-L262 HydrophobicContact CD1-CB 3.65Å; L217-L262 HydrophobicContact CG-CB 4.17Å; L230-L262 HydrophobicContact CB-CD1 4.37Å; G232-L262 VanDerWaalsContact N-CD1 3.34Å; I238-L262 HydrophobicContact CD1-CD2 4.06Å; I238-L262 HydrophobicContact CG1-CD2 4.14Å; I238-L262 HydrophobicContact CG2-CD1 4.26Å; I238-L262 HydrophobicContact CG2-CD2 4.26Å; V259-L262 HydrophobicContact CG1-CD2 3.9Å; L262-V271 HydrophobicContact CD2-CG2 3.9Å; L262-Y272 CarbonylContact C-O 3.58Å; L262-Y272 VanDerWaalsContact CA-O 3.26Å; L262-Y272 WeakPolarHBondContact CA-O 3.31Å
263Q98.7Very high96.4Very high16 Ų1637.6 Ų37.68%0.07518%0.182CC..EExtended strand (participates in β ladder)trans-134.8161.7162.3-78.9-71.5-26.300108.8Y272 M304 E305 L306Q263-Y272 HydrophobicContact CB-CD2 4.46Å; Q263-Y272 PolarHBondContact N-O 2.83Å; Q263-Y272 PolarHBondContact O-N 3.09Å; Q263-M304 HydrophobicContact CG-CB 4.09Å; Q263-M304 VanDerWaalsContact CG-O 3.31Å; Q263-M304 WeakPolarHBondContact CG-O 3.24Å; Q263-M304 PolarHBondContact NE2-O 2.98Å; Q263-E305 PolarHBondContact NE2-OE2 3.28Å; Q263-L306 HydrophobicContact CB-CD1 3.78Å; Q263-L306 HydrophobicContact CB-CG 3.82Å; Q263-L306 HydrophobicContact CG-CG 4.22Å
264V97.2Very high96.5Very high12 Ų1229.2 Ų29.27%0.07315%0.151CC..EExtended strand (participates in β ladder)trans-143.2145.5179.172.80000110.1L217 L230 F268 H270 R308L217-V264 HydrophobicContact CD1-CB 3.97Å; L217-V264 HydrophobicContact CD1-CG1 4.02Å; L230-V264 HydrophobicContact CD1-CB 4.34Å; L230-V264 HydrophobicContact CD1-CG2 4.01Å; V264-F268 HydrophobicContact CB-CD2 4.31Å; V264-F268 HydrophobicContact CG1-CD2 3.72Å; V264-F268 HydrophobicContact CG1-CE2 3.94Å; V264-F268 HydrophobicContact CG2-CB 4.5Å; V264-F268 HydrophobicContact CG2-CD2 3.74Å; V264-F268 HydrophobicContact CG2-CE2 4.21Å; V264-F268 HydrophobicContact CG2-CG 4.16Å; V264-H270 WeakPolarHBondContact CA-O 3.32Å; V264-H270 VanDerWaalsContact CG2-O 3.28Å; V264-H270 WeakPolarHBondContact CG2-O 3.22Å; V264-R308 PolarHBondContact O-NH1 3.27Å; V264-R308 PolarHBondContact O-NH2 3.04Å
265N94.4Very high96.7Very high12 Ų1228.6 Ų28.66%0.06415%0.147CC..  trans-69164.3172.372.3-27.5000111.9A267 F268 T269 H270 P313N265-A267 PolarHBondContact O-N 2.77Å; N265-F268 PolarHBondContact O-N 2.93Å; N265-F268 PolarHBondContact OD1-N 3.26Å; N265-T269 PolarHBondContact ND2-OG1 3.39Å; N265-T269 VanDerWaalsContact ND2-OG1 3.1Å; N265-T269 PolarHBondContact OD1-N 2.8Å; N265-T269 PolarHBondContact OD1-OG1 2.98Å; N265-H270 PolarHBondContact N-O 3.34Å; N265-H270 PolarHBondContact OD1-N 3.41Å; N265-P313 HydrophobicContact CB-CG 4.39Å
266E90.8Very high96.8Very high118 Ų11834.3 Ų34.355%0.55117%0.168SC*.THydrogen-bonded Turntrans-57.1-36.9-177.5-67.7-61.3134.900112.9F268 R308E266-F268 PolarHBondContact O-N 2.77Å; E266-R308 IonicContact OE1-CZ 3.91Å; E266-R308 IonicContact OE1-NH1 3.36Å; E266-R308 PolarHBondContact OE1-NH1 2.92Å
267A91.2Very high96.9Very high61 Ų6127.7 Ų27.750%0.50414%0.137SC..THydrogen-bonded Turntrans-72.9-5178.500000114.4N265 T269N265-A267 PolarHBondContact O-N 2.77Å; A267-T269 VanDerWaalsContact C-N 3.25Å; A267-T269 HydrophobicContact CB-CG2 4.27Å; A267-T269 PolarHBondContact O-N 2.88Å
268F93.2Very high96.9Very high21 Ų2127.5 Ų27.59%0.09214%0.135CC..SBendtrans54.339.1-176.4-151.9-98.3000113.6N219 Q228 L230 L240 V264 N265 E266 L285N219-F268 HydrophobicContact CB-CB 4.19Å; N219-F268 HydrophobicContact CB-CD1 3.92Å; N219-F268 HydrophobicContact CB-CD2 3.55Å; N219-F268 HydrophobicContact CB-CE1 4.12Å; N219-F268 HydrophobicContact CB-CE2 3.77Å; N219-F268 HydrophobicContact CB-CG 3.63Å; N219-F268 HydrophobicContact CB-CZ 4.04Å; Q228-F268 HydrophobicContact CB-CD1 4.44Å; Q228-F268 HydrophobicContact CB-CE1 3.78Å; Q228-F268 HydrophobicContact CB-CZ 4.42Å; L230-F268 HydrophobicContact CB-CZ 4.31Å; L230-F268 HydrophobicContact CD1-CE1 4.05Å; L230-F268 HydrophobicContact CD1-CE2 3.96Å; L230-F268 HydrophobicContact CD1-CZ 3.61Å; L230-F268 HydrophobicContact CG-CE1 4.04Å; L230-F268 HydrophobicContact CG-CE2 4.42Å; L230-F268 HydrophobicContact CG-CZ 3.64Å; L240-F268 HydrophobicContact CD1-CE1 3.8Å; V264-F268 HydrophobicContact CB-CD2 4.31Å; V264-F268 HydrophobicContact CG1-CD2 3.72Å; V264-F268 HydrophobicContact CG1-CE2 3.94Å; V264-F268 HydrophobicContact CG2-CB 4.5Å; V264-F268 HydrophobicContact CG2-CD2 3.74Å; V264-F268 HydrophobicContact CG2-CE2 4.21Å; V264-F268 HydrophobicContact CG2-CG 4.16Å; N265-F268 PolarHBondContact O-N 2.93Å; N265-F268 PolarHBondContact OD1-N 3.26Å; E266-F268 PolarHBondContact O-N 2.77Å; F268-L285 HydrophobicContact CD1-CD1 4.47Å; F268-L285 WeakPolarHBondContact O-CD1 3.31Å
269T93.1Very high96.9Very high31 Ų3129.3 Ų29.319%0.1914%0.141CC..  trans-115-23.6-177.146.20000113.1N265 A267 L285N265-T269 PolarHBondContact ND2-OG1 3.39Å; N265-T269 VanDerWaalsContact ND2-OG1 3.1Å; N265-T269 PolarHBondContact OD1-N 2.8Å; N265-T269 PolarHBondContact OD1-OG1 2.98Å; A267-T269 VanDerWaalsContact C-N 3.25Å; A267-T269 HydrophobicContact CB-CG2 4.27Å; A267-T269 PolarHBondContact O-N 2.88Å; T269-L285 WeakPolarHBondContact O-CB 3.26Å; T269-L285 WeakPolarHBondContact O-CG 3.29Å; T269-L285 PolarHBondContact O-N 3.07Å
270H95.1Very high96.9Very high18 Ų1829.3 Ų29.38%0.08314%0.141CC..EExtended strand (participates in β ladder)trans-125.3119-176.7-65.772.6000109.3V264 N265 Y272 T283 D284 R337V264-H270 WeakPolarHBondContact CA-O 3.32Å; V264-H270 VanDerWaalsContact CG2-O 3.28Å; V264-H270 WeakPolarHBondContact CG2-O 3.22Å; N265-H270 PolarHBondContact N-O 3.34Å; N265-H270 PolarHBondContact OD1-N 3.41Å; H270-Y272 HydrophobicContact CB-CE2 4.48Å; H270-T283 WeakPolarHBondContact CA-O 3.47Å; H270-D284 IonicContact CE1-OD2 2.75Å; H270-D284 IonicContact NE2-OD2 3.75Å; H270-D284 PolarHBondContact NE2-OD2 3.06Å; H270-R337 PolarHBondContact CD2-NH2 3.03Å; H270-R337 VanDerWaalsContact NE2-CZ 3.29Å; H270-R337 PolarHBondContact NE2-NH1 2.71Å; H270-R337 PolarHBondContact NE2-NH2 3.21Å
271V98.2Very high96.9Very high0 Ų028 Ų280%014%0.136CC..EExtended strand (participates in β ladder)trans-97.7133.9175.364.50000109.7L230 L262 C282 T283 L285L230-V271 HydrophobicContact CD1-CB 4.15Å; L230-V271 HydrophobicContact CD1-CG2 4.04Å; L262-V271 HydrophobicContact CD2-CG2 3.9Å; V271-C282 CarbonylContact O-C 3.54Å; V271-C282 WeakPolarHBondContact O-CA 3.42Å; V271-T283 PolarHBondContact N-O 2.93Å; V271-T283 PolarHBondContact O-N 2.69Å; V271-L285 HydrophobicContact CB-CD2 3.94Å; V271-L285 HydrophobicContact CB-CG 4.42Å; V271-L285 HydrophobicContact CG1-CD2 3.56Å; V271-L285 HydrophobicContact CG1-CG 4.3Å
272Y98.6Very high96.8Very high5 Ų528 Ų282%0.0214%0.136CC..EExtended strand (participates in β ladder)trans-103.5126.4171.7-57.9-97.5000107.5L262 Q263 H270 Y281 C282 I294 M304 L306 I316 L330 M333L262-Y272 CarbonylContact C-O 3.58Å; L262-Y272 VanDerWaalsContact CA-O 3.26Å; L262-Y272 WeakPolarHBondContact CA-O 3.31Å; Q263-Y272 HydrophobicContact CB-CD2 4.46Å; Q263-Y272 PolarHBondContact N-O 2.83Å; Q263-Y272 PolarHBondContact O-N 3.09Å; H270-Y272 HydrophobicContact CB-CE2 4.48Å; Y272-Y281 CarbonylContact C-O 3.58Å; Y272-Y281 VanDerWaalsContact CA-O 3.25Å; Y272-Y281 WeakPolarHBondContact CA-O 3.47Å; Y272-C282 HydrophobicContact CD1-CB 3.94Å; Y272-C282 HydrophobicContact CE1-CB 3.92Å; Y272-I294 HydrophobicContact CD1-CD1 3.72Å; Y272-I294 HydrophobicContact CE1-CD1 4.17Å; Y272-M304 WeakPolarHBondContact O-CE 3.42Å; Y272-L306 HydrophobicContact CD1-CD2 4.32Å; Y272-L306 HydrophobicContact CD2-CD1 3.78Å; Y272-L306 HydrophobicContact CD2-CD2 4.11Å; Y272-L306 HydrophobicContact CD2-CG 4.42Å; Y272-L306 HydrophobicContact CE1-CD2 4.25Å; Y272-L306 HydrophobicContact CE2-CD1 3.76Å; Y272-L306 HydrophobicContact CE2-CD2 4.04Å; Y272-L306 HydrophobicContact CG-CD2 4.25Å; Y272-I316 HydrophobicContact CD1-CD1 4.33Å; Y272-I316 HydrophobicContact CG-CD1 4.34Å; Y272-L330 HydrophobicContact CD1-CD1 4.47Å; Y272-L330 HydrophobicContact CE1-CD1 3.7Å; Y272-L330 HydrophobicContact CE1-CD2 4.34Å; Y272-M333 HydrophobicContact CE1-CE 4.4Å; Y272-M333 HydrophobicContact CE1-SD 4.43Å
273S98.8Very high96.7Very high0 Ų027.7 Ų27.70%014%0.135CC..EExtended strand (participates in β ladder)trans-133.9142.6-173.461.20000112.6I238 H255 A261 I280 Y281I238-S273 WeakPolarHBondContact CD1-OG 3.39Å; H255-S273 VanDerWaalsContact NE2-CB 3.31Å; H255-S273 WeakPolarHBondContact NE2-CB 3.49Å; H255-S273 PolarHBondContact NE2-O 3.07Å; H255-S273 PolarHBondContact NE2-OG 3.43Å; A261-S273 WeakPolarHBondContact O-CA 3.49Å; S273-I280 VanDerWaalsContact O-CA 3.32Å; S273-I280 WeakPolarHBondContact O-CA 3.32Å; S273-Y281 PolarHBondContact N-O 2.98Å; S273-Y281 PolarHBondContact O-N 3.24Å
274G98.8Very high96.4Very high0 Ų027.2 Ų27.20%013%0.133CC..EExtended strand (participates in β ladder)trans-154.2155.2177.100000111.4W260 A261W260-G274 PolarHBondContact N-O 3.15Å; A261-G274 PolarHBondContact N-O 3.05Å; A261-G274 PolarHBondContact O-N 3.41Å
275G98.6Very high96.3Very high0 Ų027.5 Ų27.50%013%0.134CC..EExtended strand (participates in β ladder)trans-169.4-139.3-18000000114.1G258 D277 K278 V301G258-G275 WeakPolarHBondContact O-CA 3.4Å; G275-D277 VanDerWaalsContact C-N 3.35Å; G275-D277 PolarHBondContact O-N 2.96Å; G275-K278 PolarHBondContact O-N 3Å; G275-V301 PolarHBondContact O-N 3.03Å
276R98.6Very high96.2Very high137 Ų13735.2 Ų35.252%0.51716%0.162SC..THydrogen-bonded Turntrans-67.3-34-170.8-169.1175.8166.8152.15.7113.6E257 G258 W260 K278E257-R276 HydrophobicContact CB-CB 3.8Å; E257-R276 HydrophobicContact CB-CG 4.27Å; E257-R276 WeakPolarHBondContact OE2-CD 3.39Å; E257-R276 WeakPolarHBondContact OE2-CG 2.98Å; E257-R276 IonicContact OE2-CZ 3.52Å; E257-R276 IonicContact OE2-NE 2.78Å; E257-R276 PolarHBondContact OE2-NE 3.12Å; G258-R276 PolarHBondContact O-N 2.98Å; W260-R276 HydrophobicContact CD2-CB 4.48Å; W260-R276 HydrophobicContact CH2-CB 3.75Å; W260-R276 HydrophobicContact CH2-CG 3.69Å; W260-R276 HydrophobicContact CZ2-CB 3.56Å; W260-R276 HydrophobicContact CZ2-CG 3.76Å; W260-R276 HydrophobicContact CZ3-CB 4.29Å; R276-K278 PolarHBondContact O-N 2.8Å
277D97.9Very high96.1Very high11 Ų1132.6 Ų32.66%0.05915%0.152CC..THydrogen-bonded Turntrans-73.5-1.8178.263.82.7000113.9H255 E256 E257 G275 K279H255-D277 VanDerWaalsContact CA-OD2 3.31Å; H255-D277 WeakPolarHBondContact CA-OD2 3.33Å; H255-D277 VanDerWaalsContact CB-OD2 3.22Å; H255-D277 WeakPolarHBondContact CB-OD2 3.42Å; H255-D277 IonicContact CE1-OD1 2.83Å; H255-D277 IonicContact CG-OD2 2.71Å; H255-D277 VanDerWaalsContact ND1-CG 3.31Å; H255-D277 IonicContact ND1-OD1 3.25Å; H255-D277 PolarHBondContact ND1-OD1 3.01Å; H255-D277 IonicContact ND1-OD2 3.85Å; H255-D277 PolarHBondContact ND1-OD2 3.12Å; E256-D277 PolarHBondContact N-OD2 3.11Å; E257-D277 HydrophobicContact CB-CB 4.13Å; E257-D277 HydrophobicContact CG-CB 4.33Å; G275-D277 VanDerWaalsContact C-N 3.35Å; G275-D277 PolarHBondContact O-N 2.96Å; D277-K279 PolarHBondContact O-N 2.8Å; D277-K279 PolarHBondContact OD1-N 2.88Å
278K98.6Very high95.9Very high78 Ų7832.3 Ų32.334%0.33915%0.145SC..  trans67.8-11.6176.1-39.8170.3-168.41580115.4G275 R276 E296 E297G275-K278 PolarHBondContact O-N 3Å; R276-K278 PolarHBondContact O-N 2.8Å; K278-E296 HydrophobicContact CB-CG 4.34Å; K278-E297 HydrophobicContact CB-CB 4.38Å; K278-E297 WeakPolarHBondContact CB-O 3.25Å; K278-E297 WeakPolarHBondContact CD-O 3.24Å; K278-E297 PolarHBondContact O-N 3.25Å
279K98.3Very high95.5Very high44 Ų4437.9 Ų37.919%0.19118%0.176CC..EExtended strand (participates in β ladder)trans-74.2143.7177.4-61.8-179.4-169.2167.60109.5H255 E256 D277 Y281 L293 E296H255-K279 PolarHBondContact CE1-O 2.79Å; E256-K279 IonicContact OE1-NZ 3.54Å; E256-K279 PolarHBondContact OE1-NZ 3.21Å; D277-K279 PolarHBondContact O-N 2.8Å; D277-K279 PolarHBondContact OD1-N 2.88Å; K279-Y281 HydrophobicContact CB-CD2 4.32Å; K279-Y281 HydrophobicContact CB-CE2 3.57Å; K279-Y281 HydrophobicContact CD-CE2 4.23Å; K279-Y281 WeakPolarHBondContact CD-OH 3.32Å; K279-L293 HydrophobicContact CB-CD1 3.93Å; K279-L293 HydrophobicContact CG-CD1 4.35Å; K279-E296 HydrophobicContact CG-CG 4.26Å
280I98.6Very high95.3Very high0 Ų039 Ų390%018%0.18CC..EExtended strand (participates in β ladder)trans-120.2121.4176.5-56.3-176.8000108.9S273 I294 C295 E297 V301 M304 V318S273-I280 VanDerWaalsContact O-CA 3.32Å; S273-I280 WeakPolarHBondContact O-CA 3.32Å; I280-I294 HydrophobicContact CB-CB 4.45Å; I280-I294 HydrophobicContact CG2-CB 4.31Å; I280-I294 HydrophobicContact CG2-CD1 4.01Å; I280-I294 WeakPolarHBondContact O-CB 3.35Å; I280-I294 PolarHBondContact O-N 3.32Å; I280-C295 PolarHBondContact N-O 2.91Å; I280-E297 HydrophobicContact CD1-CG 4.15Å; I280-V301 HydrophobicContact CD1-CG2 3.95Å; I280-V301 HydrophobicContact CG1-CG2 3.98Å; I280-M304 HydrophobicContact CD1-SD 4.19Å; I280-M304 HydrophobicContact CG1-SD 4.49Å; I280-M304 HydrophobicContact CG2-SD 3.8Å; I280-V318 HydrophobicContact CD1-CB 4.28Å; I280-V318 HydrophobicContact CD1-CG1 3.71Å; I280-V318 HydrophobicContact CD1-CG2 3.6Å
281Y97.8Very high95Very high16 Ų1641.8 Ų41.86%0.06319%0.19CC..EExtended strand (participates in β ladder)trans-113.6148-178.5-65.8-80.7000111.6V254 H255 Y272 S273 K279 V292 L293 L350V254-Y281 HydrophobicContact CB-CD2 4.39Å; V254-Y281 HydrophobicContact CG2-CD2 4.21Å; V254-Y281 HydrophobicContact CG2-CG 4.47Å; V254-Y281 VanDerWaalsContact O-CE2 3.26Å; V254-Y281 WeakPolarHBondContact O-CE2 3.47Å; H255-Y281 AromaticContact CE1-CD2 3.6Å; H255-Y281 AromaticContact NE2-CD2 3.83Å; Y272-Y281 CarbonylContact C-O 3.58Å; Y272-Y281 VanDerWaalsContact CA-O 3.25Å; Y272-Y281 WeakPolarHBondContact CA-O 3.47Å; S273-Y281 PolarHBondContact N-O 2.98Å; S273-Y281 PolarHBondContact O-N 3.24Å; K279-Y281 HydrophobicContact CB-CD2 4.32Å; K279-Y281 HydrophobicContact CB-CE2 3.57Å; K279-Y281 HydrophobicContact CD-CE2 4.23Å; K279-Y281 WeakPolarHBondContact CD-OH 3.32Å; Y281-V292 CarbonylContact C-O 3.32Å; Y281-V292 WeakPolarHBondContact CA-O 3.44Å; Y281-L293 HydrophobicContact CD1-CB 4.16Å; Y281-L293 HydrophobicContact CD1-CD1 4.11Å; Y281-L293 HydrophobicContact CE1-CB 3.89Å; Y281-L293 HydrophobicContact CE1-CD1 3.68Å; Y281-L293 HydrophobicContact CE1-CG 4.33Å; Y281-L293 HydrophobicContact CE2-CD1 4.44Å; Y281-L350 HydrophobicContact CE1-CD1 4.11Å
282C97.3Very high94.8Very high1 Ų142.1 Ų42.11%0.00719%0.192CC..EExtended strand (participates in β ladder)trans-107.7123.6156.4-176.90000108.8V271 Y272 R291 V292 I294 M333V271-C282 CarbonylContact O-C 3.54Å; V271-C282 WeakPolarHBondContact O-CA 3.42Å; Y272-C282 HydrophobicContact CD1-CB 3.94Å; Y272-C282 HydrophobicContact CE1-CB 3.92Å; C282-R291 CarbonylContact O-C 3.56Å; C282-R291 VanDerWaalsContact O-CA 3.31Å; C282-R291 WeakPolarHBondContact O-CA 3.41Å; C282-V292 PolarHBondContact N-O 2.87Å; C282-V292 PolarHBondContact O-N 3.12Å; C282-I294 HydrophobicContact CB-CD1 3.96Å; C282-I294 HydrophobicContact CB-CG1 4.4Å; C282-M333 HydrophobicContact CB-CE 3.73Å; C282-M333 WeakPolarHBondContact SG-CE 3.46Å
283T96Very high94.6Very high0 Ų042.6 Ų42.60%019%0.194CC..EExtended strand (participates in β ladder)trans-120.9131.6-178-50.90000110.1V254 H270 V271V254-T283 HydrophobicContact CG1-CG2 4.39Å; H270-T283 WeakPolarHBondContact CA-O 3.47Å; V271-T283 PolarHBondContact N-O 2.93Å; V271-T283 PolarHBondContact O-N 2.69Å
284D94Very high94.5Very high6 Ų642.6 Ų42.63%0.03219%0.194CC..EExtended strand (participates in β ladder)trans-75.1123.2170.3-168.9-41.5000109.6H270 R286 N287 I290H270-D284 IonicContact CE1-OD2 2.75Å; H270-D284 IonicContact NE2-OD2 3.75Å; H270-D284 PolarHBondContact NE2-OD2 3.06Å; D284-R286 PolarHBondContact O-N 3.46Å; D284-R286 VanDerWaalsContact OD1-CB 3.3Å; D284-R286 WeakPolarHBondContact OD1-CB 3.17Å; D284-R286 IonicContact OD1-CZ 2.83Å; D284-R286 PolarHBondContact OD1-N 2.92Å; D284-R286 IonicContact OD1-NE 2.77Å; D284-R286 PolarHBondContact OD1-NE 3.25Å; D284-R286 IonicContact OD1-NH2 3.37Å; D284-R286 IonicContact OD2-CZ 2.78Å; D284-R286 IonicContact OD2-NE 2.86Å; D284-R286 IonicContact OD2-NH2 2.81Å; D284-R286 PolarHBondContact OD2-NH2 3.31Å; D284-N287 CarbonylContact O-C 3.59Å; D284-N287 PolarHBondContact O-N 3.32Å; D284-N287 VanDerWaalsContact O-O 3.13Å; D284-I290 HydrophobicContact CB-CB 4.22Å; D284-I290 HydrophobicContact CB-CG2 4.49Å; D284-I290 PolarHBondContact N-O 2.73Å; D284-I290 VanDerWaalsContact N-O 3.08Å
285L93.6Very high94.4Very high19 Ų1942.6 Ų42.610%0.09919%0.194CC..SBendtrans-69.9-18.5-177.4-64.2173.2000113.1L230 Y252 F268 T269 V271L230-L285 HydrophobicContact CD1-CD1 3.99Å; L230-L285 HydrophobicContact CD2-CD1 4.31Å; L230-L285 HydrophobicContact CD2-CD2 3.78Å; Y252-L285 HydrophobicContact CD2-CD2 4.33Å; Y252-L285 HydrophobicContact CE2-CD2 3.5Å; Y252-L285 VanDerWaalsContact CE2-CD2 3.5Å; Y252-L285 PolarHBondContact OH-O 2.88Å; F268-L285 HydrophobicContact CD1-CD1 4.47Å; F268-L285 WeakPolarHBondContact O-CD1 3.31Å; T269-L285 WeakPolarHBondContact O-CB 3.26Å; T269-L285 WeakPolarHBondContact O-CG 3.29Å; T269-L285 PolarHBondContact O-N 3.07Å; V271-L285 HydrophobicContact CB-CD2 3.94Å; V271-L285 HydrophobicContact CB-CG 4.42Å; V271-L285 HydrophobicContact CG1-CD2 3.56Å; V271-L285 HydrophobicContact CG1-CG 4.3Å
286R92.4Very high94.4Very high174 Ų17448.1 Ų48.166%0.65722%0.22SC*.SBendtrans-89.7-30.4179.5-55.6164.7-64.3173.15.5111.4D284D284-R286 PolarHBondContact O-N 3.46Å; D284-R286 VanDerWaalsContact OD1-CB 3.3Å; D284-R286 WeakPolarHBondContact OD1-CB 3.17Å; D284-R286 IonicContact OD1-CZ 2.83Å; D284-R286 PolarHBondContact OD1-N 2.92Å; D284-R286 IonicContact OD1-NE 2.77Å; D284-R286 PolarHBondContact OD1-NE 3.25Å; D284-R286 IonicContact OD1-NH2 3.37Å; D284-R286 IonicContact OD2-CZ 2.78Å; D284-R286 IonicContact OD2-NE 2.86Å; D284-R286 IonicContact OD2-NH2 2.81Å; D284-R286 PolarHBondContact OD2-NH2 3.31Å
287N89.7Confident94.4Very high62 Ų6242 Ų4233%0.33220%0.197SC..  trans-137.995.4177.1-173.2-9.2000109.9D284 D289 I290D284-N287 CarbonylContact O-C 3.59Å; D284-N287 PolarHBondContact O-N 3.32Å; D284-N287 VanDerWaalsContact O-O 3.13Å; N287-D289 PolarHBondContact O-N 2.9Å; N287-D289 PolarHBondContact OD1-N 3.43Å; N287-I290 HydrophobicContact CB-CD1 3.95Å; N287-I290 HydrophobicContact CB-CG1 4.14Å; N287-I290 WeakPolarHBondContact O-CB 3.16Å; N287-I290 PolarHBondContact O-N 2.9Å
288P86.9Confident94.3Very high56 Ų5649.7 Ų49.736%0.36423%0.23SC..THydrogen-bonded Turntrans-70.1-15.6-172.331.2-37.5000114.3Y252 I290Y252-P288 HydrophobicContact CD1-CB 3.64Å; Y252-P288 HydrophobicContact CE1-CB 3.92Å; P288-I290 PolarHBondContact O-N 3.21Å
289D85.3Confident94.3Very high138 Ų13846.3 Ų46.374%0.73822%0.217SC*.THydrogen-bonded Turntrans-69.6-23.9173.8-57.2-33.2000110.7N287 R291N287-D289 PolarHBondContact O-N 2.9Å; N287-D289 PolarHBondContact OD1-N 3.43Å; D289-R291 PolarHBondContact O-N 3.23Å; D289-R291 VanDerWaalsContact O-N 3.1Å
290I88Confident94.4Very high53 Ų5345.6 Ų45.627%0.27222%0.217SC..  trans-82.289.6172.1-53177.6000109D284 N287 P288D284-I290 HydrophobicContact CB-CB 4.22Å; D284-I290 HydrophobicContact CB-CG2 4.49Å; D284-I290 PolarHBondContact N-O 2.73Å; D284-I290 VanDerWaalsContact N-O 3.08Å; N287-I290 HydrophobicContact CB-CD1 3.95Å; N287-I290 HydrophobicContact CB-CG1 4.14Å; N287-I290 WeakPolarHBondContact O-CB 3.16Å; N287-I290 PolarHBondContact O-N 2.9Å; P288-I290 PolarHBondContact O-N 3.21Å
291R89.7Confident94.4Very high78 Ų7845.6 Ų45.629%0.29422%0.217SC..EExtended strand (participates in β ladder)trans-126.5142.2173.264.7-177178.8-179.4-1.3111.7C282 D289 L350C282-R291 CarbonylContact O-C 3.56Å; C282-R291 VanDerWaalsContact O-CA 3.31Å; C282-R291 WeakPolarHBondContact O-CA 3.41Å; D289-R291 PolarHBondContact O-N 3.23Å; D289-R291 VanDerWaalsContact O-N 3.1Å; R291-L350 HydrophobicContact CG-CD1 4.07Å
292V92.4Very high94.4Very high7 Ų745.9 Ų45.94%0.04222%0.219CC..EExtended strand (participates in β ladder)trans-118.1124.5175.5179.40000108.1Y281 C282 I294 L353Y281-V292 CarbonylContact C-O 3.32Å; Y281-V292 WeakPolarHBondContact CA-O 3.44Å; C282-V292 PolarHBondContact N-O 2.87Å; C282-V292 PolarHBondContact O-N 3.12Å; V292-I294 PolarHBondContact O-N 3.23Å; V292-L353 HydrophobicContact CG1-CB 4.31Å
293L95.2Very high94.5Very high15 Ų1548.7 Ų48.78%0.07923%0.231CC..EExtended strand (participates in β ladder)trans-73.6110.4165.7177.963.4000107.7K279 Y281 C295 L350 P352 L353K279-L293 HydrophobicContact CB-CD1 3.93Å; K279-L293 HydrophobicContact CG-CD1 4.35Å; Y281-L293 HydrophobicContact CD1-CB 4.16Å; Y281-L293 HydrophobicContact CD1-CD1 4.11Å; Y281-L293 HydrophobicContact CE1-CB 3.89Å; Y281-L293 HydrophobicContact CE1-CD1 3.68Å; Y281-L293 HydrophobicContact CE1-CG 4.33Å; Y281-L293 HydrophobicContact CE2-CD1 4.44Å; L293-C295 WeakPolarHBondContact CD1-O 3.34Å; L293-L350 HydrophobicContact CB-CB 4.04Å; L293-L350 HydrophobicContact CD2-CB 4.42Å; L293-L350 WeakPolarHBondContact CD2-O 3.5Å; L293-P352 HydrophobicContact CD2-CB 4.06Å; L293-P352 HydrophobicContact CG-CB 4.16Å; L293-P352 CarbonylContact O-C 3.55Å; L293-P352 WeakPolarHBondContact O-CA 3.47Å; L293-L353 PolarHBondContact O-N 2.74Å
294I96.4Very high94.6Very high0 Ų048.8 Ų48.80%023%0.232CC..EExtended strand (participates in β ladder)trans-72.4-53.7179.7-66.8164.2000109.4Y272 I280 C282 V292 W328 L330 L353 C354Y272-I294 HydrophobicContact CD1-CD1 3.72Å; Y272-I294 HydrophobicContact CE1-CD1 4.17Å; I280-I294 HydrophobicContact CB-CB 4.45Å; I280-I294 HydrophobicContact CG2-CB 4.31Å; I280-I294 HydrophobicContact CG2-CD1 4.01Å; I280-I294 WeakPolarHBondContact O-CB 3.35Å; I280-I294 PolarHBondContact O-N 3.32Å; C282-I294 HydrophobicContact CB-CD1 3.96Å; C282-I294 HydrophobicContact CB-CG1 4.4Å; V292-I294 PolarHBondContact O-N 3.23Å; I294-W328 HydrophobicContact CG2-CB 4.43Å; I294-L330 HydrophobicContact CD1-CD2 3.64Å; I294-L330 HydrophobicContact CG1-CD2 3.96Å; I294-L330 HydrophobicContact CG2-CD2 3.88Å; I294-L353 PolarHBondContact O-N 3Å; I294-C354 PolarHBondContact O-N 3.01Å
295C97.3Very high94.9Very high0 Ų049.7 Ų49.70%024%0.236CC..EExtended strand (participates in β ladder)trans-164170179.560.40000110.7I280 L293 W328I280-C295 PolarHBondContact N-O 2.91Å; L293-C295 WeakPolarHBondContact CD1-O 3.34Å; C295-W328 HydrophobicContact CB-CD2 3.9Å; C295-W328 HydrophobicContact CB-CE3 3.6Å; C295-W328 HydrophobicContact CB-CH2 3.82Å; C295-W328 HydrophobicContact CB-CZ2 4.12Å; C295-W328 HydrophobicContact CB-CZ3 3.55Å; C295-W328 VanDerWaalsContact SG-CD2 3.5Å; C295-W328 VanDerWaalsContact SG-CE2 3.55Å
296E97.9Very high95.1Very high115 Ų11548.9 Ų48.954%0.53723%0.231SC..EExtended strand (participates in β ladder)trans-113.5119.4164.4-173.2-179.5163.400108.7K278 K279K278-E296 HydrophobicContact CB-CG 4.34Å; K279-E296 HydrophobicContact CG-CG 4.26Å
297E98.3Very high95.3Very high8 Ų841.4 Ų41.44%0.03721%0.205CC..  trans-75.9159.9178.8-94.5-67.9177.600112.8K278 I280 A299 V301 V318 T320 N326 W328K278-E297 HydrophobicContact CB-CB 4.38Å; K278-E297 WeakPolarHBondContact CB-O 3.25Å; K278-E297 WeakPolarHBondContact CD-O 3.24Å; K278-E297 PolarHBondContact O-N 3.25Å; I280-E297 HydrophobicContact CD1-CG 4.15Å; E297-A299 PolarHBondContact O-N 2.89Å; E297-V301 HydrophobicContact CB-CG2 4.15Å; E297-V301 HydrophobicContact CG-CG2 4.18Å; E297-V318 HydrophobicContact CG-CG1 3.93Å; E297-T320 HydrophobicContact CB-CG2 4.18Å; E297-T320 HydrophobicContact CG-CG2 3.95Å; E297-N326 WeakPolarHBondContact OE1-CB 3.44Å; E297-N326 PolarHBondContact OE1-ND2 2.81Å; E297-N326 PolarHBondContact OE2-ND2 3.2Å; E297-W328 PolarHBondContact OE1-NE1 3.3Å
298K97.6Very high95.6Very high174 Ų17443.1 Ų43.176%0.75721%0.206SC*.SBendtrans-75.5-8.4179.1-63.5-176-179.1178.60113.5K322K298-K322 HydrophobicContact CB-CD 4.21Å
299A98.4Very high95.9Very high6 Ų644.5 Ų44.55%0.0522%0.218CC..SBendtrans-157.9160.3-176.400000111E297 V301 T321 K322E297-A299 PolarHBondContact O-N 2.89Å; A299-V301 PolarHBondContact O-N 3.33Å; A299-T321 WeakPolarHBondContact CB-OG1 3.27Å; A299-K322 HydrophobicContact CB-CB 4.45Å; A299-K322 HydrophobicContact CB-CD 3.94Å; A299-K322 HydrophobicContact CB-CG 3.76Å
300P98.8Very high96.2Very high30 Ų3040.5 Ų40.520%0.19520%0.204CC..  trans-50.6130.6178.7-32.737.3000113.2W260 T320 T321W260-P300 HydrophobicContact CE3-CB 4.48Å; W260-P300 HydrophobicContact CH2-CB 4.33Å; W260-P300 HydrophobicContact CZ3-CB 3.67Å; P300-T320 VanDerWaalsContact O-CA 3.23Å; P300-T320 WeakPolarHBondContact O-CA 3.45Å; P300-T320 VanDerWaalsContact O-CB 3.28Å; P300-T320 WeakPolarHBondContact O-CB 3.41Å; P300-T321 HydrophobicContact CB-CG2 4.27Å; P300-T321 PolarHBondContact O-N 3.24Å; P300-T321 VanDerWaalsContact O-N 3.15Å
301V98.9Very high96.2Very high0 Ų043.5 Ų43.50%022%0.22CC..EExtended strand (participates in β ladder)trans-76.4128.5-179.1177.30000109.5A261 G275 I280 E297 A299 M304 V318A261-V301 HydrophobicContact CB-CG1 4.15Å; G275-V301 PolarHBondContact O-N 3.03Å; I280-V301 HydrophobicContact CD1-CG2 3.95Å; I280-V301 HydrophobicContact CG1-CG2 3.98Å; E297-V301 HydrophobicContact CB-CG2 4.15Å; E297-V301 HydrophobicContact CG-CG2 4.18Å; A299-V301 PolarHBondContact O-N 3.33Å; V301-M304 HydrophobicContact CG1-CG 3.84Å; V301-M304 HydrophobicContact CG1-SD 4.28Å; V301-V318 HydrophobicContact CG1-CG1 3.99Å; V301-V318 HydrophobicContact CG2-CG1 4.12Å
302L98.9Very high96.2Very high22 Ų2243.2 Ų43.212%0.11523%0.228CC..EExtended strand (participates in β ladder)trans-103.4-43-179.1-62.7-177.9000112.3R50 W260 S319 T320 T321R50-L302 VanDerWaalsContact NH2-CD1 3.32Å; W260-L302 HydrophobicContact CE3-CD2 3.92Å; W260-L302 HydrophobicContact CZ3-CD2 4.03Å; L302-S319 PolarHBondContact N-O 3.38Å; L302-T320 WeakPolarHBondContact CD1-O 3.04Å; L302-T321 HydrophobicContact CD1-CG2 4.09Å; L302-T321 HydrophobicContact CD2-CG2 3.97Å; L302-T321 HydrophobicContact CG-CG2 4.18Å
303K98.9Very high96.4Very high60 Ų6043.3 Ų43.326%0.26123%0.229SC..EExtended strand (participates in β ladder)trans-150.8158.2178.5-152.790.2176.9-154.10110N34 D80 S319N34-K303 WeakPolarHBondContact O-CB 3.34Å; D80-K303 IonicContact OD1-NZ 3.82Å; D80-K303 PolarHBondContact OD1-NZ 2.81Å; D80-K303 IonicContact OD2-NZ 2.78Å; K303-S319 WeakPolarHBondContact CB-OG 3.46Å; K303-S319 PolarHBondContact N-O 3.34Å; K303-S319 PolarHBondContact N-OG 3.08Å; K303-S319 PolarHBondContact O-N 3.32Å; K303-S319 PolarHBondContact O-OG 2.69Å
304M98.9Very high96.4Very high1 Ų144 Ų441%0.00523%0.234CC..EExtended strand (participates in β ladder)trans-136.7149.7173.7-56.9-179-66.400109.2A261 Q263 Y272 I280 V301 I316 W317 V318A261-M304 HydrophobicContact CB-CE 3.95Å; A261-M304 HydrophobicContact CB-CG 4.1Å; A261-M304 WeakPolarHBondContact O-CE 3.4Å; Q263-M304 HydrophobicContact CG-CB 4.09Å; Q263-M304 VanDerWaalsContact CG-O 3.31Å; Q263-M304 WeakPolarHBondContact CG-O 3.24Å; Q263-M304 PolarHBondContact NE2-O 2.98Å; Y272-M304 WeakPolarHBondContact O-CE 3.42Å; I280-M304 HydrophobicContact CD1-SD 4.19Å; I280-M304 HydrophobicContact CG1-SD 4.49Å; I280-M304 HydrophobicContact CG2-SD 3.8Å; V301-M304 HydrophobicContact CG1-CG 3.84Å; V301-M304 HydrophobicContact CG1-SD 4.28Å; M304-I316 HydrophobicContact CB-CD1 3.83Å; M304-I316 HydrophobicContact CB-CG1 4.08Å; M304-I316 HydrophobicContact CG-CD1 4.32Å; M304-I316 HydrophobicContact SD-CD1 3.83Å; M304-W317 CarbonylContact C-O 3.57Å; M304-W317 WeakPolarHBondContact CA-O 3.47Å; M304-V318 HydrophobicContact CG-CG1 4.47Å; M304-V318 HydrophobicContact CG-CG2 4.24Å
305E98.8Very high96.5Very high26 Ų2644 Ų4412%0.12124%0.235CC..EExtended strand (participates in β ladder)trans-137.2118.5176.4-173.261-164.300109.6L36 L38 Q263 W317L36-E305 HydrophobicContact CB-CB 3.84Å; L36-E305 HydrophobicContact CD1-CB 4.38Å; L38-E305 HydrophobicContact CB-CG 3.98Å; Q263-E305 PolarHBondContact NE2-OE2 3.28Å; E305-W317 HydrophobicContact CB-CB 4.44Å; E305-W317 PolarHBondContact N-O 2.8Å; E305-W317 PolarHBondContact O-N 3.27Å
306L98.4Very high96.5Very high1 Ų144 Ų441%0.00524%0.235CC..EExtended strand (participates in β ladder)trans-72.5140.2179.6-76.4169.9000110.7Q263 Y272 R308 P313 I316 L330Q263-L306 HydrophobicContact CB-CD1 3.78Å; Q263-L306 HydrophobicContact CB-CG 3.82Å; Q263-L306 HydrophobicContact CG-CG 4.22Å; Y272-L306 HydrophobicContact CD1-CD2 4.32Å; Y272-L306 HydrophobicContact CD2-CD1 3.78Å; Y272-L306 HydrophobicContact CD2-CD2 4.11Å; Y272-L306 HydrophobicContact CD2-CG 4.42Å; Y272-L306 HydrophobicContact CE1-CD2 4.25Å; Y272-L306 HydrophobicContact CE2-CD1 3.76Å; Y272-L306 HydrophobicContact CE2-CD2 4.04Å; Y272-L306 HydrophobicContact CG-CD2 4.25Å; L306-R308 HydrophobicContact CB-CG 4.2Å; L306-R308 PolarHBondContact O-N 2.81Å; L306-P313 HydrophobicContact CD1-CG 4.31Å; L306-P313 HydrophobicContact CD2-CB 3.99Å; L306-P313 HydrophobicContact CD2-CG 4.42Å; L306-I316 HydrophobicContact CD2-CB 3.98Å; L306-I316 HydrophobicContact CD2-CD1 3.83Å; L306-I316 HydrophobicContact CD2-CG1 3.91Å; L306-I316 HydrophobicContact CG-CD1 4.38Å; L306-I316 HydrophobicContact CG-CG1 4.46Å; L306-L330 HydrophobicContact CD2-CD1 3.93Å
307D97.2Very high96.6Very high18 Ų1838.6 Ų38.610%0.09621%0.21CC..  trans-72.6111161.5-168-30.7000107.5L38 S309 P314 A315 K327L38-D307 HydrophobicContact CD2-CB 4.46Å; D307-S309 VanDerWaalsContact OD1-CB 3.28Å; D307-S309 WeakPolarHBondContact OD1-CB 3.27Å; D307-S309 PolarHBondContact OD1-N 2.88Å; D307-S309 PolarHBondContact OD1-OG 2.91Å; D307-P314 HydrophobicContact CB-CG 4.15Å; D307-P314 WeakPolarHBondContact O-CD 3.28Å; D307-A315 HydrophobicContact CB-CB 4.11Å; D307-A315 WeakPolarHBondContact CB-O 3.24Å; D307-A315 PolarHBondContact N-O 2.78Å; D307-K327 IonicContact OD2-NZ 2.83Å; D307-K327 PolarHBondContact OD2-NZ 2.88Å
308R95.2Very high96.6Very high97 Ų9738.2 Ų38.237%0.36621%0.208SC..  trans-9921.8-175.6-63.1-178.7-178.9-86.4-10.4112.9V264 E266 L306 A310V264-R308 PolarHBondContact O-NH1 3.27Å; V264-R308 PolarHBondContact O-NH2 3.04Å; E266-R308 IonicContact OE1-CZ 3.91Å; E266-R308 IonicContact OE1-NH1 3.36Å; E266-R308 PolarHBondContact OE1-NH1 2.92Å; L306-R308 HydrophobicContact CB-CG 4.2Å; L306-R308 PolarHBondContact O-N 2.81Å; R308-A310 VanDerWaalsContact C-N 3.3Å; R308-A310 PolarHBondContact O-N 3.15Å
309S93.4Very high96.7Very high86 Ų8629.9 Ų29.960%0.60117%0.172SC*.SBendtrans-72.9-17.8-179.655.60000114.3D307D307-S309 VanDerWaalsContact OD1-CB 3.28Å; D307-S309 WeakPolarHBondContact OD1-CB 3.27Å; D307-S309 PolarHBondContact OD1-N 2.88Å; D307-S309 PolarHBondContact OD1-OG 2.91Å
310A92.5Very high96.7Very high54 Ų5429.7 Ų29.745%0.44617%0.17SC..SBendtrans-145.8163.6175.800000111.6R308 P312 P313R308-A310 VanDerWaalsContact C-N 3.3Å; R308-A310 PolarHBondContact O-N 3.15Å; A310-P312 CarbonylContact C-O 3.58Å; A310-P312 CarbonylContact O-C 3.2Å; A310-P312 VanDerWaalsContact O-C 3.31Å; A310-P313 WeakPolarHBondContact O-CA 3.14Å
311D87.6Confident96.7Very high116 Ų11630.6 Ų30.662%0.6218%0.175SC*.SBendtrans-121.1117.1169.9-170.723.9000108.9
312P90.4Very high96.7Very high71 Ų7135.4 Ų35.446%0.46120%0.196SC..SBendcis-65.8155.81.732.5-40.5000113.6A310A310-P312 CarbonylContact C-O 3.58Å; A310-P312 CarbonylContact O-C 3.2Å; A310-P312 VanDerWaalsContact O-C 3.31Å
313P95.4Very high96.7Very high9 Ų935.1 Ų35.16%0.05820%0.196CC..  trans-54.5127.3175.8-26.334.5000111.7N265 L306 A310 A315 L330N265-P313 HydrophobicContact CB-CG 4.39Å; L306-P313 HydrophobicContact CD1-CG 4.31Å; L306-P313 HydrophobicContact CD2-CB 3.99Å; L306-P313 HydrophobicContact CD2-CG 4.42Å; A310-P313 WeakPolarHBondContact O-CA 3.14Å; P313-A315 PolarHBondContact O-N 3.15Å; P313-L330 HydrophobicContact CB-CD1 4.22Å; P313-L330 WeakPolarHBondContact O-CB 3.45Å
314P95.8Very high96.7Very high29 Ų2933.8 Ų33.819%0.18819%0.194CC..  trans-76.5-22.9-174.827.8-35.2000113.7D307 L330D307-P314 HydrophobicContact CB-CG 4.15Å; D307-P314 WeakPolarHBondContact O-CD 3.28Å; P314-L330 PolarHBondContact O-N 3.39Å
315A97.6Very high96.7Very high2 Ų233.7 Ų33.72%0.01719%0.193CC..EExtended strand (participates in β ladder)trans-160.1166.7-174.900000112.4D307 P313 K327 W328D307-A315 HydrophobicContact CB-CB 4.11Å; D307-A315 WeakPolarHBondContact CB-O 3.24Å; D307-A315 PolarHBondContact N-O 2.78Å; P313-A315 PolarHBondContact O-N 3.15Å; A315-K327 HydrophobicContact CB-CD 4.18Å; A315-K327 HydrophobicContact CB-CG 3.96Å; A315-W328 CarbonylContact C-O 3.5Å; A315-W328 WeakPolarHBondContact CA-O 3.48Å; A315-W328 WeakPolarHBondContact CB-O 3.46Å
316I98.7Very high96.6Very high0 Ų033 Ų330%019%0.191CC..EExtended strand (participates in β ladder)trans-133.3129.7174.3-166.8167.1000110.7Y272 M304 L306 V318 K327 W328 L330Y272-I316 HydrophobicContact CD1-CD1 4.33Å; Y272-I316 HydrophobicContact CG-CD1 4.34Å; M304-I316 HydrophobicContact CB-CD1 3.83Å; M304-I316 HydrophobicContact CB-CG1 4.08Å; M304-I316 HydrophobicContact CG-CD1 4.32Å; M304-I316 HydrophobicContact SD-CD1 3.83Å; L306-I316 HydrophobicContact CD2-CB 3.98Å; L306-I316 HydrophobicContact CD2-CD1 3.83Å; L306-I316 HydrophobicContact CD2-CG1 3.91Å; L306-I316 HydrophobicContact CG-CD1 4.38Å; L306-I316 HydrophobicContact CG-CG1 4.46Å; I316-V318 HydrophobicContact CG2-CG2 4.26Å; I316-K327 WeakPolarHBondContact O-CA 3.4Å; I316-W328 HydrophobicContact CG2-CB 3.98Å; I316-W328 PolarHBondContact N-O 3.31Å; I316-W328 PolarHBondContact O-N 3.27Å; I316-L330 HydrophobicContact CB-CD1 4.24Å; I316-L330 HydrophobicContact CG2-CD2 4.14Å; I316-L330 HydrophobicContact CG2-CG 4.43Å
317W98.8Very high96.7Very high0 Ų033.7 Ų33.70%019%0.194CC..EExtended strand (participates in β ladder)trans-86137.8169.6-73.796.6000110L36 L45 V59 M304 E305 V325 N326 K327 Q359 I361L36-W317 HydrophobicContact CD1-CB 3.95Å; L45-W317 HydrophobicContact CD1-CB 4.46Å; L45-W317 HydrophobicContact CD1-CD2 4.38Å; L45-W317 HydrophobicContact CD1-CG 4.17Å; L45-W317 HydrophobicContact CD2-CD2 3.83Å; L45-W317 HydrophobicContact CD2-CE3 3.65Å; L45-W317 HydrophobicContact CD2-CG 4.38Å; L45-W317 HydrophobicContact CD2-CH2 4.35Å; L45-W317 HydrophobicContact CD2-CZ3 3.92Å; V59-W317 HydrophobicContact CB-CZ2 3.83Å; V59-W317 HydrophobicContact CG1-CH2 4.18Å; V59-W317 HydrophobicContact CG1-CZ2 3.44Å; V59-W317 VanDerWaalsContact CG1-CZ2 3.44Å; M304-W317 CarbonylContact C-O 3.57Å; M304-W317 WeakPolarHBondContact CA-O 3.47Å; E305-W317 HydrophobicContact CB-CB 4.44Å; E305-W317 PolarHBondContact N-O 2.8Å; E305-W317 PolarHBondContact O-N 3.27Å; W317-V325 HydrophobicContact CE3-CG1 4Å; W317-V325 HydrophobicContact CZ3-CG1 4.46Å; W317-N326 CarbonylContact C-O 3.59Å; W317-N326 WeakPolarHBondContact CA-O 3.4Å; W317-K327 HydrophobicContact CD2-CB 3.83Å; W317-K327 HydrophobicContact CD2-CD 4.44Å; W317-K327 HydrophobicContact CD2-CG 4.12Å; W317-K327 HydrophobicContact CE3-CB 3.77Å; W317-K327 HydrophobicContact CH2-CB 3.9Å; W317-K327 HydrophobicContact CH2-CD 4.4Å; W317-K327 HydrophobicContact CZ2-CB 3.93Å; W317-K327 HydrophobicContact CZ2-CD 3.68Å; W317-K327 HydrophobicContact CZ2-CG 4.16Å; W317-K327 HydrophobicContact CZ3-CB 3.82Å; W317-Q359 HydrophobicContact CH2-CB 4.38Å; W317-Q359 HydrophobicContact CH2-CG 4.16Å; W317-I361 HydrophobicContact CH2-CD1 3.95Å; W317-I361 HydrophobicContact CH2-CG1 4.26Å; W317-I361 HydrophobicContact CZ3-CD1 3.65Å; W317-I361 HydrophobicContact CZ3-CG1 4.02Å
318V98.9Very high96.7Very high0 Ų033.3 Ų33.30%019%0.191CC..EExtended strand (participates in β ladder)trans-131.2128.2-173.2-178.60000110.1I280 E297 V301 M304 I316 T320 V325 N326I280-V318 HydrophobicContact CD1-CB 4.28Å; I280-V318 HydrophobicContact CD1-CG1 3.71Å; I280-V318 HydrophobicContact CD1-CG2 3.6Å; E297-V318 HydrophobicContact CG-CG1 3.93Å; V301-V318 HydrophobicContact CG1-CG1 3.99Å; V301-V318 HydrophobicContact CG2-CG1 4.12Å; M304-V318 HydrophobicContact CG-CG1 4.47Å; M304-V318 HydrophobicContact CG-CG2 4.24Å; I316-V318 HydrophobicContact CG2-CG2 4.26Å; V318-T320 HydrophobicContact CG1-CG2 4.24Å; V318-V325 WeakPolarHBondContact O-CG1 3.15Å; V318-N326 PolarHBondContact N-O 3.43Å; V318-N326 PolarHBondContact O-N 2.87Å
319S98.9Very high96.8Very high0 Ų029.8 Ų29.80%018%0.181CC..EExtended strand (participates in β ladder)trans-109.3143.8171.276.70000111.1V33 L302 K303V33-S319 WeakPolarHBondContact O-CB 3.29Å; V33-S319 PolarHBondContact O-OG 2.96Å; L302-S319 PolarHBondContact N-O 3.38Å; K303-S319 WeakPolarHBondContact CB-OG 3.46Å; K303-S319 PolarHBondContact N-O 3.34Å; K303-S319 PolarHBondContact N-OG 3.08Å; K303-S319 PolarHBondContact O-N 3.32Å; K303-S319 PolarHBondContact O-OG 2.69Å
320T98.9Very high96.9Very high1 Ų126 Ų261%0.00615%0.154CC..EExtended strand (participates in β ladder)trans-132.4-176.8-176.771.70000110.7V33 E297 P300 L302 V318 K322V33-T320 PolarHBondContact N-O 3.08Å; V33-T320 VanDerWaalsContact N-O 3.15Å; E297-T320 HydrophobicContact CB-CG2 4.18Å; E297-T320 HydrophobicContact CG-CG2 3.95Å; P300-T320 VanDerWaalsContact O-CA 3.23Å; P300-T320 WeakPolarHBondContact O-CA 3.45Å; P300-T320 VanDerWaalsContact O-CB 3.28Å; P300-T320 WeakPolarHBondContact O-CB 3.41Å; L302-T320 WeakPolarHBondContact CD1-O 3.04Å; V318-T320 HydrophobicContact CG1-CG2 4.24Å; T320-K322 PolarHBondContact O-N 3.49Å; T320-K322 PolarHBondContact OG1-N 3.27Å; T320-K322 VanDerWaalsContact OG1-N 3.08Å
321T98.7Very high96.6Very high49 Ų4930.3 Ų30.330%0.30116%0.162SC..SBendtrans-66.9-12.5168.953.80000113.8G32 A299 P300 L302G32-T321 WeakPolarHBondContact CA-O 3.4Å; A299-T321 WeakPolarHBondContact CB-OG1 3.27Å; P300-T321 HydrophobicContact CB-CG2 4.27Å; P300-T321 PolarHBondContact O-N 3.24Å; P300-T321 VanDerWaalsContact O-N 3.15Å; L302-T321 HydrophobicContact CD1-CG2 4.09Å; L302-T321 HydrophobicContact CD2-CG2 3.97Å; L302-T321 HydrophobicContact CG-CG2 4.18Å
322K98.7Very high96.2Very high101 Ų10126.4 Ų26.444%0.43915%0.15SC..SBendtrans-82.7156.6168.1-71.6177.1177.9-70.50110.9G32 K298 A299 T320 S324G32-K322 WeakPolarHBondContact CA-O 3.12Å; K298-K322 HydrophobicContact CB-CD 4.21Å; A299-K322 HydrophobicContact CB-CB 4.45Å; A299-K322 HydrophobicContact CB-CD 3.94Å; A299-K322 HydrophobicContact CB-CG 3.76Å; T320-K322 PolarHBondContact O-N 3.49Å; T320-K322 PolarHBondContact OG1-N 3.27Å; T320-K322 VanDerWaalsContact OG1-N 3.08Å; K322-S324 VanDerWaalsContact C-N 3.35Å
323S98.6Very high95.6Very high17 Ų1723.9 Ų23.912%0.11913%0.132CC..SBendtrans-73.6-20.7-179.7480000115N29 N31 G363 G364N29-S323 PolarHBondContact ND2-O 3.19Å; N29-S323 WeakPolarHBondContact O-CB 3.37Å; N31-S323 WeakPolarHBondContact O-CA 3.34Å; S323-G363 WeakPolarHBondContact OG-CA 3.48Å; S323-G364 WeakPolarHBondContact CB-O 3.39Å; S323-G364 PolarHBondContact OG-O 3.06Å
324S98.5Very high94.3Very high31 Ų3128.5 Ų28.522%0.21715%0.152CC..  trans-74.8146.1174.756.50000111.7K322 I361K322-S324 VanDerWaalsContact C-N 3.35Å; S324-I361 WeakPolarHBondContact CA-O 3.44Å
325V98.8Very high92.6Very high0 Ų033 Ų330%018%0.175CC..EExtended strand (participates in β ladder)trans-122.1129.4177-1770000109V33 L36 L45 T47 W317 V318 I361V33-V325 HydrophobicContact CB-CG2 4.15Å; V33-V325 HydrophobicContact CG1-CG2 4.3Å; V33-V325 HydrophobicContact CG2-CG2 3.8Å; L36-V325 HydrophobicContact CD1-CG1 4.32Å; L36-V325 HydrophobicContact CD2-CG1 3.99Å; L45-V325 HydrophobicContact CD2-CG1 4.19Å; T47-V325 HydrophobicContact CG2-CG2 3.99Å; W317-V325 HydrophobicContact CE3-CG1 4Å; W317-V325 HydrophobicContact CZ3-CG1 4.46Å; V318-V325 WeakPolarHBondContact O-CG1 3.15Å; V325-I361 HydrophobicContact CB-CB 4.22Å; V325-I361 HydrophobicContact CB-CD1 4.48Å; V325-I361 PolarHBondContact N-O 3.17Å; V325-I361 VanDerWaalsContact N-O 3.08Å; V325-I361 PolarHBondContact O-N 3.08Å
326N98.7Very high90.6Very high12 Ų1237.2 Ų37.26%0.06419%0.193CC..EExtended strand (participates in β ladder)trans-112.7143.6-172-64.4-30.4000111.1E297 W317 V318 P357E297-N326 WeakPolarHBondContact OE1-CB 3.44Å; E297-N326 PolarHBondContact OE1-ND2 2.81Å; E297-N326 PolarHBondContact OE2-ND2 3.2Å; W317-N326 CarbonylContact C-O 3.59Å; W317-N326 WeakPolarHBondContact CA-O 3.4Å; V318-N326 PolarHBondContact N-O 3.43Å; V318-N326 PolarHBondContact O-N 2.87Å; N326-P357 HydrophobicContact CB-CB 3.98Å
327K98.5Very high88.6Confident15 Ų1541 Ų417%0.06521%0.207CC..EExtended strand (participates in β ladder)trans-104.4126.3165.7-172.3177.2-179164.20108.5D307 A315 I316 W317 P357 E358 Q359D307-K327 IonicContact OD2-NZ 2.83Å; D307-K327 PolarHBondContact OD2-NZ 2.88Å; A315-K327 HydrophobicContact CB-CD 4.18Å; A315-K327 HydrophobicContact CB-CG 3.96Å; I316-K327 WeakPolarHBondContact O-CA 3.4Å; W317-K327 HydrophobicContact CD2-CB 3.83Å; W317-K327 HydrophobicContact CD2-CD 4.44Å; W317-K327 HydrophobicContact CD2-CG 4.12Å; W317-K327 HydrophobicContact CE3-CB 3.77Å; W317-K327 HydrophobicContact CH2-CB 3.9Å; W317-K327 HydrophobicContact CH2-CD 4.4Å; W317-K327 HydrophobicContact CZ2-CB 3.93Å; W317-K327 HydrophobicContact CZ2-CD 3.68Å; W317-K327 HydrophobicContact CZ2-CG 4.16Å; W317-K327 HydrophobicContact CZ3-CB 3.82Å; K327-P357 CarbonylContact O-C 3.57Å; K327-P357 WeakPolarHBondContact O-CA 3.36Å; K327-P357 WeakPolarHBondContact O-CB 3.26Å; K327-E358 PolarHBondContact O-N 3.08Å; K327-Q359 HydrophobicContact CB-CB 3.89Å; K327-Q359 HydrophobicContact CD-CB 4.47Å; K327-Q359 PolarHBondContact N-O 2.81Å; K327-Q359 PolarHBondContact O-N 3.28Å
328W98.3Very high86.2Confident10 Ų1045.9 Ų45.94%0.03824%0.241CC..EExtended strand (participates in β ladder)trans-110.2133.9177.4-63.392000110I294 C295 E297 A315 I316 C354 P357I294-W328 HydrophobicContact CG2-CB 4.43Å; C295-W328 HydrophobicContact CB-CD2 3.9Å; C295-W328 HydrophobicContact CB-CE3 3.6Å; C295-W328 HydrophobicContact CB-CH2 3.82Å; C295-W328 HydrophobicContact CB-CZ2 4.12Å; C295-W328 HydrophobicContact CB-CZ3 3.55Å; C295-W328 VanDerWaalsContact SG-CD2 3.5Å; C295-W328 VanDerWaalsContact SG-CE2 3.55Å; E297-W328 PolarHBondContact OE1-NE1 3.3Å; A315-W328 CarbonylContact C-O 3.5Å; A315-W328 WeakPolarHBondContact CA-O 3.48Å; A315-W328 WeakPolarHBondContact CB-O 3.46Å; I316-W328 HydrophobicContact CG2-CB 3.98Å; I316-W328 PolarHBondContact N-O 3.31Å; I316-W328 PolarHBondContact O-N 3.27Å; W328-C354 HydrophobicContact CE3-CB 3.57Å; W328-C354 HydrophobicContact CZ3-CB 3.88Å; W328-P357 HydrophobicContact CD2-CB 4.29Å; W328-P357 HydrophobicContact CE3-CB 4.42Å; W328-P357 HydrophobicContact CZ2-CB 4.36Å
329S96.5Very high83.8Confident22 Ų2249.3 Ų49.315%0.15427%0.266CS..EExtended strand (participates in β ladder)trans-75.1141.7178.7-143.10000110.5C354 E358S329-C354 PolarHBondContact O-SG 3.23Å; S329-E358 WeakPolarHBondContact CA-OE2 3.28Å; S329-E358 WeakPolarHBondContact CB-OE2 3.38Å; S329-E358 PolarHBondContact OG-OE2 2.99Å
330L95.3Very high81.3Confident7 Ų751.7 Ų51.74%0.03729%0.29CS..  trans-109.75.9174.1-61.5178.5000111.8Y272 I294 L306 P313 P314 I316 M333Y272-L330 HydrophobicContact CD1-CD1 4.47Å; Y272-L330 HydrophobicContact CE1-CD1 3.7Å; Y272-L330 HydrophobicContact CE1-CD2 4.34Å; I294-L330 HydrophobicContact CD1-CD2 3.64Å; I294-L330 HydrophobicContact CG1-CD2 3.96Å; I294-L330 HydrophobicContact CG2-CD2 3.88Å; L306-L330 HydrophobicContact CD2-CD1 3.93Å; P313-L330 HydrophobicContact CB-CD1 4.22Å; P313-L330 WeakPolarHBondContact O-CB 3.45Å; P314-L330 PolarHBondContact O-N 3.39Å; I316-L330 HydrophobicContact CB-CD1 4.24Å; I316-L330 HydrophobicContact CG2-CD2 4.14Å; I316-L330 HydrophobicContact CG2-CG 4.43Å; L330-M333 HydrophobicContact CB-SD 3.84Å; L330-M333 HydrophobicContact CD2-SD 3.98Å; L330-M333 HydrophobicContact CG-SD 4.34Å; L330-M333 WeakPolarHBondContact O-CG 3.43Å; L330-M333 PolarHBondContact O-N 3.34Å
331K87.9Confident78.7Confident144 Ų14459.4 Ų59.463%0.62633%0.326SS*.THydrogen-bonded Turntrans-61.6137.6174.7-65.2178-178170.30109.8
332G77.5Confident76.3Confident34 Ų3465.9 Ų65.935%0.35135%0.346SS..THydrogen-bonded Turntrans89.2-1.1178.800000115.6H334 N335G332-H334 PolarHBondContact O-N 2.83Å; G332-H334 VanDerWaalsContact O-N 3.12Å; G332-N335 WeakPolarHBondContact O-CB 3.4Å; G332-N335 PolarHBondContact O-N 3.45Å
333M78.1Confident73.7Confident18 Ų1865.7 Ų65.79%0.08935%0.35CS..THydrogen-bonded Turntrans-54.4-31.3174.7-83.2177.460.700113.8Y272 C282 L330 L353Y272-M333 HydrophobicContact CE1-CE 4.4Å; Y272-M333 HydrophobicContact CE1-SD 4.43Å; C282-M333 HydrophobicContact CB-CE 3.73Å; C282-M333 WeakPolarHBondContact SG-CE 3.46Å; L330-M333 HydrophobicContact CB-SD 3.84Å; L330-M333 HydrophobicContact CD2-SD 3.98Å; L330-M333 HydrophobicContact CG-SD 4.34Å; L330-M333 WeakPolarHBondContact O-CG 3.43Å; L330-M333 PolarHBondContact O-N 3.34Å; M333-L353 HydrophobicContact CG-CD2 3.68Å
334H69.2Low71Confident106 Ų10672.8 Ų72.849%0.49139%0.386SS..THydrogen-bonded Turntrans-71.1-28.2177.3-67.6-73.3000113.5G332 R337 S338G332-H334 PolarHBondContact O-N 2.83Å; G332-H334 VanDerWaalsContact O-N 3.12Å; H334-R337 WeakPolarHBondContact O-CB 3.34Å; H334-R337 PolarHBondContact O-N 3.12Å; H334-S338 PolarHBondContact O-OG 2.77Å
335N60.1Low68.4Low123 Ų12375.9 Ų75.966%0.65840%0.4SS*.Hα-helixtrans-73-33.7-178.5-64.6-8.4000111.2G332 R337 S338 S339G332-N335 WeakPolarHBondContact O-CB 3.4Å; G332-N335 PolarHBondContact O-N 3.45Å; N335-R337 PolarHBondContact O-N 2.81Å; N335-S338 PolarHBondContact O-N 3.48Å; N335-S339 PolarHBondContact O-N 3.48Å
336F54.5Low66Low91 Ų9181.4 Ų81.440%0.39944%0.438SS..Hα-helixtrans-67.8-19.2175-130-88.2000113
337R56.2Low63.5Low79 Ų7986 Ų8630%0.29847%0.467SS..Hα-helixtrans-82.4-23.8175.1-66.7180168.5-159.1-16.2113.2H270 H334 N335H270-R337 PolarHBondContact CD2-NH2 3.03Å; H270-R337 VanDerWaalsContact NE2-CZ 3.29Å; H270-R337 PolarHBondContact NE2-NH1 2.71Å; H270-R337 PolarHBondContact NE2-NH2 3.21Å; H334-R337 WeakPolarHBondContact O-CB 3.34Å; H334-R337 PolarHBondContact O-N 3.12Å; N335-R337 PolarHBondContact O-N 2.81Å
338S49.4Very low61.3Low103 Ų10388.5 Ų88.572%0.7248%0.483SS*.Hα-helixtrans-94.9-15.3-174-55.70000113.4H334 N335 G340H334-S338 PolarHBondContact O-OG 2.77Å; N335-S338 PolarHBondContact O-N 3.48Å; S338-G340 PolarHBondContact O-N 2.82Å
339S48.9Very low59.5Low73 Ų7393.7 Ų93.751%0.5152%0.518SS..SBendtrans-74.9-2.3-176.460.20000114.7N335 E341N335-S339 PolarHBondContact O-N 3.48Å; S339-E341 PolarHBondContact O-N 2.88Å
340G46Very low58.6Low49 Ų4995.6 Ų95.651%0.50553%0.526SS..  trans65.67.8164.300000116.3S338 Y342S338-G340 PolarHBondContact O-N 2.82Å; G340-Y342 PolarHBondContact O-N 3.32Å
341E44.1Very low58.1Low163 Ų16399.9 Ų99.976%0.76255%0.553SS**  trans-74.671.3166.6-70.5-179.3178.500108.4S339 D343S339-E341 PolarHBondContact O-N 2.88Å; E341-D343 PolarHBondContact O-N 3.11Å
342Y48.5Very low58.4Low186 Ų18695.1 Ų95.173%0.72954%0.537SS*.  trans-69.470.5159.2-66.7-81.2000107.3G340 N344G340-Y342 PolarHBondContact O-N 3.32Å; Y342-N344 PolarHBondContact O-N 3.27Å
343D43.8Very low59.1Low97 Ų9795.4 Ų95.452%0.51953%0.53SS..  trans-6894169.4-108.90.6000106.8E341 D345 T348E341-D343 PolarHBondContact O-N 3.11Å; D343-D345 PolarHBondContact O-N 3.37Å; D343-D345 VanDerWaalsContact O-N 3.12Å; D343-T348 WeakPolarHBondContact OD2-CG2 3.18Å; D343-T348 PolarHBondContact OD2-OG1 3.33Å
344N42.9Very low59.8Low165 Ų16595.6 Ų95.688%0.88253%0.533SS*.  trans-62.7-4.1167.5-92.8-22.2000112.1Y342Y342-N344 PolarHBondContact O-N 3.27Å
345D42.8Very low61Low96 Ų9696.3 Ų96.351%0.51355%0.545SS..  trans-93.5105.2-179.8-134.1-31.9000109.6D343 T347 T348D343-D345 PolarHBondContact O-N 3.37Å; D343-D345 VanDerWaalsContact O-N 3.12Å; D345-T347 PolarHBondContact O-N 3.45Å; D345-T347 PolarHBondContact OD1-OG1 2.68Å; D345-T348 PolarHBondContact O-N 2.92Å
346C47.9Very low62.7Low117 Ų11797.7 Ų97.779%0.79155%0.547SS*.THydrogen-bonded Turntrans-62.411.2173.1-94.20000113.9
347T46.2Very low64.8Low108 Ų10895.3 Ų95.366%0.66354%0.541SS*.THydrogen-bonded Turntrans-106.7-16.6-172.7590000113.5D345D345-T347 PolarHBondContact O-N 3.45Å; D345-T347 PolarHBondContact OD1-OG1 2.68Å
348T52.4Low66.7Low67 Ų6794.8 Ų94.841%0.41154%0.542SS..SBendtrans-83.7124.8175.550.10000110.9D343 D345 L350D343-T348 WeakPolarHBondContact OD2-CG2 3.18Å; D343-T348 PolarHBondContact OD2-OG1 3.33Å; D345-T348 PolarHBondContact O-N 2.92Å; T348-L350 PolarHBondContact O-N 2.9Å
349P61.3Low68.9Low119 Ų11991 Ų9177%0.77351%0.513SS*.PPolyproline II helixtrans-67.5120.7179.323.4-29.2000110.3T351P349-T351 PolarHBondContact O-N 3.08Å
350L77.2Confident71.2Confident63 Ų6391 Ų9133%0.3351%0.51SS..PPolyproline II helixtrans-57.9127.9176.4-70.6169.6000110.3Y281 R291 L293 T348Y281-L350 HydrophobicContact CE1-CD1 4.11Å; R291-L350 HydrophobicContact CG-CD1 4.07Å; L293-L350 HydrophobicContact CB-CB 4.04Å; L293-L350 HydrophobicContact CD2-CB 4.42Å; L293-L350 WeakPolarHBondContact CD2-O 3.5Å; T348-L350 PolarHBondContact O-N 2.9Å
351T86Confident73.7Confident97 Ų9788.7 Ų88.760%0.59549%0.486SS*.PPolyproline II helixtrans-74.8131173.9-590000109.4P349P349-T351 PolarHBondContact O-N 3.08Å
352P92.4Very high76.3Confident44 Ų4487.7 Ų87.729%0.28648%0.479SS..PPolyproline II helixtrans-68.9141-179.627.9-34.8000111.7L293 C354 T355L293-P352 HydrophobicContact CD2-CB 4.06Å; L293-P352 HydrophobicContact CG-CB 4.16Å; L293-P352 CarbonylContact O-C 3.55Å; L293-P352 WeakPolarHBondContact O-CA 3.47Å; P352-C354 VanDerWaalsContact C-N 3.28Å; P352-C354 PolarHBondContact O-N 3.31Å; P352-T355 HydrophobicContact CG-CG2 4.26Å
353L92.6Very high78.6Confident40 Ų4080.2 Ų80.221%0.20946%0.458CS..SBendtrans-60-39.9174.1179.566.5000111.7V292 L293 I294 M333V292-L353 HydrophobicContact CG1-CB 4.31Å; L293-L353 PolarHBondContact O-N 2.74Å; I294-L353 PolarHBondContact O-N 3Å; M333-L353 HydrophobicContact CG-CD2 3.68Å
354C94.3Very high81.2Confident21 Ų2176.3 Ų76.314%0.14244%0.441CS..  trans-127.1130.3-179.4-68.20000110.7I294 W328 S329 P352I294-C354 PolarHBondContact O-N 3.01Å; W328-C354 HydrophobicContact CE3-CB 3.57Å; W328-C354 HydrophobicContact CZ3-CB 3.88Å; S329-C354 PolarHBondContact O-SG 3.23Å; P352-C354 VanDerWaalsContact C-N 3.28Å; P352-C354 PolarHBondContact O-N 3.31Å
355T94.3Very high83.8Confident121 Ų12169.1 Ų69.174%0.74240%0.404SS*.SBendtrans-98.5-17.7172.955.20000112.8P352P352-T355 HydrophobicContact CG-CG2 4.26Å
356Q95.8Very high86.5Confident152 Ų15265 Ų6571%0.7138%0.384SS*.SBendtrans-136.5147.5176.4-63.5-173.15.800110.9
357P97.2Very high88.9Confident42 Ų4259.9 Ų59.927%0.27335%0.348SS..  trans-71146.2177.229.7-35.5000111.7N326 K327 W328 Q359 V360N326-P357 HydrophobicContact CB-CB 3.98Å; K327-P357 CarbonylContact O-C 3.57Å; K327-P357 WeakPolarHBondContact O-CA 3.36Å; K327-P357 WeakPolarHBondContact O-CB 3.26Å; W328-P357 HydrophobicContact CD2-CB 4.29Å; W328-P357 HydrophobicContact CE3-CB 4.42Å; W328-P357 HydrophobicContact CZ2-CB 4.36Å; P357-Q359 VanDerWaalsContact C-N 3.35Å; P357-V360 HydrophobicContact CB-CG2 4.03Å; P357-V360 HydrophobicContact CG-CG2 3.34Å
358E95.9Very high91.4Very high67 Ų6759 Ų5931%0.31334%0.339SS..SBendtrans-68.6-34.5174.9-177.2177.816700111.5Q61 K327 S329Q61-E358 PolarHBondContact NE2-OE1 2.91Å; K327-E358 PolarHBondContact O-N 3.08Å; S329-E358 WeakPolarHBondContact CA-OE2 3.28Å; S329-E358 WeakPolarHBondContact CB-OE2 3.38Å; S329-E358 PolarHBondContact OG-OE2 2.99Å
359Q96.4Very high93.6Very high25 Ų2560 Ų6012%0.11734%0.339CS..EExtended strand (participates in β ladder)trans-146.4144.4176.6-171.6179.3-10.100110.4V59 W317 K327 P357V59-Q359 PolarHBondContact O-OE1 2.95Å; W317-Q359 HydrophobicContact CH2-CB 4.38Å; W317-Q359 HydrophobicContact CH2-CG 4.16Å; K327-Q359 HydrophobicContact CB-CB 3.89Å; K327-Q359 HydrophobicContact CD-CB 4.47Å; K327-Q359 PolarHBondContact N-O 2.81Å; K327-Q359 PolarHBondContact O-N 3.28Å; P357-Q359 VanDerWaalsContact C-N 3.35Å
360V97.6Very high95.4Very high72 Ų7256.3 Ų56.344%0.43632%0.315SS..EExtended strand (participates in β ladder)trans-127.1121.3178.6-178.10000110.2P357P357-V360 HydrophobicContact CB-CG2 4.03Å; P357-V360 HydrophobicContact CG-CG2 3.34Å
361I98.4Very high96.4Very high0 Ų056.5 Ų56.50%031%0.314CS..EExtended strand (participates in β ladder)trans-85.7119.7163-64.5168.5000107.3L45 W57 W317 S324 V325L45-I361 HydrophobicContact CD2-CD1 3.58Å; W57-I361 HydrophobicContact CB-CD1 3.91Å; W57-I361 HydrophobicContact CD2-CD1 4.13Å; W57-I361 HydrophobicContact CD2-CG2 3.7Å; W57-I361 HydrophobicContact CE3-CG2 3.66Å; W57-I361 HydrophobicContact CG-CD1 3.76Å; W57-I361 HydrophobicContact CG-CG2 4.45Å; W57-I361 HydrophobicContact CH2-CG2 3.72Å; W57-I361 HydrophobicContact CZ2-CG2 3.74Å; W57-I361 HydrophobicContact CZ3-CG2 3.68Å; W317-I361 HydrophobicContact CH2-CD1 3.95Å; W317-I361 HydrophobicContact CH2-CG1 4.26Å; W317-I361 HydrophobicContact CZ3-CD1 3.65Å; W317-I361 HydrophobicContact CZ3-CG1 4.02Å; S324-I361 WeakPolarHBondContact CA-O 3.44Å; V325-I361 HydrophobicContact CB-CB 4.22Å; V325-I361 HydrophobicContact CB-CD1 4.48Å; V325-I361 PolarHBondContact N-O 3.17Å; V325-I361 VanDerWaalsContact N-O 3.08Å; V325-I361 PolarHBondContact O-N 3.08Å
362K98.1Very high97Very high142 Ų14254 Ų5462%0.61730%0.297SS*.  trans-63.9144.4-178.6-64.2-178.6-178.3176.90110.9Y28Y28-K362 HydrophobicContact CD1-CB 4.03Å; Y28-K362 VanDerWaalsContact CD1-O 3.26Å; Y28-K362 WeakPolarHBondContact CD1-O 3.36Å; Y28-K362 HydrophobicContact CE1-CB 3.9Å
363G97.7Very high97.3Very high29 Ų2952.4 Ų52.430%0.29929%0.286SS..  trans-108.3151.7172.600000111.5S323S323-G363 WeakPolarHBondContact OG-CA 3.48Å
364G97.8Very high97.5Very high16 Ų1652.3 Ų52.317%0.16529%0.285CS..PPolyproline II helixtrans-85.6168.3168.800000111.7N29 S323N29-G364 WeakPolarHBondContact O-CA 3.08Å; N29-G364 PolarHBondContact O-N 2.8Å; S323-G364 WeakPolarHBondContact CB-O 3.39Å; S323-G364 PolarHBondContact OG-O 3.06Å
365A98.4Very high97.6Very high13 Ų1352.8 Ų52.811%0.10729%0.286CS..PPolyproline II helixtrans-82137178.700000111.6R30 D383 T384R30-A365 PolarHBondContact NE-O 3.35Å; R30-A365 PolarHBondContact NH2-O 2.67Å; A365-D383 HydrophobicContact CB-CB 3.97Å; A365-D383 WeakPolarHBondContact CB-OD2 3.35Å; A365-T384 WeakPolarHBondContact CA-OG1 3.15Å
366S98.7Very high97.8Very high11 Ų1148.4 Ų48.48%0.07726%0.257CS..PPolyproline II helixtrans-91.1137.6173.9-47.20000109.9R30 N31 I368 D383 T384R30-S366 VanDerWaalsContact O-CA 3.26Å; R30-S366 WeakPolarHBondContact O-CA 3.49Å; R30-S366 WeakPolarHBondContact O-CB 3.46Å; R30-S366 PolarHBondContact O-OG 3.07Å; N31-S366 WeakPolarHBondContact CA-OG 3.31Å; S366-I368 PolarHBondContact O-N 2.81Å; S366-D383 CarbonylContact O-C 3.21Å; S366-D383 WeakPolarHBondContact O-CA 3.36Å; S366-D383 WeakPolarHBondContact O-CB 3.48Å; S366-T384 PolarHBondContact N-OG1 3.06Å; S366-T384 VanDerWaalsContact N-OG1 3.14Å; S366-T384 PolarHBondContact O-N 3.13Å
367I98.8Very high97.9Very high8 Ų842.2 Ų42.24%0.04123%0.227CC..EExtended strand (participates in β ladder)trans-71.6125.6166.5-61.9173.4000108.3T381 W391 L428 G431 L433I367-T381 HydrophobicContact CD1-CG2 4.37Å; I367-T381 HydrophobicContact CG2-CG2 3.87Å; I367-W391 HydrophobicContact CD1-CH2 4.46Å; I367-W391 HydrophobicContact CD1-CZ2 4.08Å; I367-L428 HydrophobicContact CB-CD2 4.27Å; I367-L428 HydrophobicContact CG2-CD1 3.98Å; I367-L428 HydrophobicContact CG2-CD2 3.68Å; I367-L428 HydrophobicContact CG2-CG 4.44Å; I367-G431 PolarHBondContact N-O 3.18Å; I367-L433 HydrophobicContact CD1-CD1 4.25Å; I367-L433 HydrophobicContact CD1-CG 3.79Å
368I98.3Very high97.9Very high91 Ų9141.7 Ų41.747%0.46722%0.221SC..EExtended strand (participates in β ladder)trans-120.7-19.5-174.555.8169.2000113.3S366 K382 T384S366-I368 PolarHBondContact O-N 2.81Å; I368-K382 VanDerWaalsContact CG1-O 3.32Å; I368-K382 WeakPolarHBondContact CG1-O 3.41Å; I368-K382 PolarHBondContact N-O 3.06Å; I368-T384 HydrophobicContact CG2-CG2 3.66Å
369Q98.4Very high98Very high88 Ų8838.5 Ų38.541%0.41121%0.206SC..EExtended strand (participates in β ladder)trans-133147.1171.8-60.8-178.5-56.400110T381 K382 F407Q369-T381 VanDerWaalsContact O-CA 3.25Å; Q369-T381 WeakPolarHBondContact O-CA 3.23Å; Q369-T381 WeakPolarHBondContact O-CB 3.46Å; Q369-K382 HydrophobicContact CB-CB 4.06Å; Q369-K382 PolarHBondContact N-O 2.8Å; Q369-K382 PolarHBondContact O-N 3.25Å; Q369-K382 VanDerWaalsContact OE1-CD 3.23Å; Q369-F407 HydrophobicContact CB-CE1 4.06Å; Q369-F407 HydrophobicContact CB-CZ 4.23Å
370C98.4Very high98.1Very high41 Ų4137.3 Ų37.328%0.27720%0.2SC..EExtended strand (participates in β ladder)trans-145134.6-179.4172.80000109I379 L380 T381 L428C370-I379 WeakPolarHBondContact SG-CG2 3.16Å; C370-L380 CarbonylContact C-O 3.56Å; C370-L380 WeakPolarHBondContact CA-O 3.32Å; C370-T381 HydrophobicContact CB-CG2 4.44Å; C370-L428 HydrophobicContact CB-CD1 3.97Å; C370-L428 HydrophobicContact CB-CD2 4.32Å; C370-L428 HydrophobicContact CB-CG 4.48Å
371H98.7Very high98.2Very high66 Ų6634 Ų3431%0.30618%0.181SC..EExtended strand (participates in β ladder)trans-129121.9174-174.888.9000109.5I379 L380 F407 I411H371-I379 WeakPolarHBondContact O-CA 3.23Å; H371-L380 PolarHBondContact N-O 2.88Å; H371-L380 PolarHBondContact O-N 2.81Å; H371-F407 HydrophobicContact CB-CE1 4.3Å; H371-F407 HydrophobicContact CB-CZ 3.9Å; H371-I411 HydrophobicContact CB-CD1 3.62Å; H371-I411 HydrophobicContact CB-CG1 4.06Å; H371-I411 WeakPolarHBondContact NE2-CG2 3.31Å
372I98.6Very high98.2Very high45 Ų4535.7 Ų35.723%0.23119%0.188CC..EExtended strand (participates in β ladder)trans-87.6120.4177.1-55170.4000108.1K376 I379 F424 V426I372-K376 HydrophobicContact CG2-CD 3.82Å; I372-I379 HydrophobicContact CG1-CD1 4.37Å; I372-I379 HydrophobicContact CG1-CG1 4.17Å; I372-F424 HydrophobicContact CD1-CE2 3.81Å; I372-F424 HydrophobicContact CD1-CZ 4.22Å; I372-F424 HydrophobicContact CG1-CE2 4.21Å; I372-F424 HydrophobicContact CG1-CZ 4.4Å; I372-F424 HydrophobicContact CG2-CE2 4.35Å; I372-F424 HydrophobicContact CG2-CZ 3.71Å; I372-V426 HydrophobicContact CD1-CG2 3.88Å; I372-V426 HydrophobicContact CG1-CG2 4.21Å
373L98.1Very high98.3Very high11 Ų1130.1 Ų30.16%0.05817%0.165CC..  trans-69.1166.9179.5-65.5176.2000111.9D375 K376 H378 Y390 R414L373-D375 PolarHBondContact O-N 3.33Å; L373-K376 PolarHBondContact O-N 3.3Å; L373-K376 VanDerWaalsContact O-N 3.09Å; L373-K376 PolarHBondContact O-NZ 3.08Å; L373-H378 WeakPolarHBondContact CB-O 3.36Å; L373-H378 HydrophobicContact CD1-CB 3.83Å; L373-H378 PolarHBondContact N-O 3.08Å; L373-Y390 HydrophobicContact CD1-CD2 4.42Å; L373-Y390 HydrophobicContact CD1-CE2 3.67Å; L373-R414 HydrophobicContact CD1-CB 4.31Å; L373-R414 HydrophobicContact CD2-CB 4.3Å
374N97.3Very high98.3Very high38 Ų3831.8 Ų31.820%0.20317%0.169CC..THydrogen-bonded Turntrans-65-24.1-173.9-78-11.2000114.1K376 F415 K416 V418 V420N374-K376 PolarHBondContact O-N 3.14Å; N374-F415 WeakPolarHBondContact ND2-CD2 3.25Å; N374-F415 WeakPolarHBondContact ND2-CE2 3.32Å; N374-K416 WeakPolarHBondContact CB-O 3.44Å; N374-K416 PolarHBondContact ND2-O 2.79Å; N374-V418 HydrophobicContact CB-CG1 4.09Å; N374-V418 WeakPolarHBondContact CB-O 3.45Å; N374-V420 PolarHBondContact O-N 3.28Å
375D96.4Very high98.3Very high31 Ų3135.3 Ų35.317%0.16618%0.184CC..THydrogen-bonded Turntrans-73.5-7.7175.86313.2000113.8L373 R377 H378 V418L373-D375 PolarHBondContact O-N 3.33Å; D375-R377 PolarHBondContact O-N 3.12Å; D375-R377 VanDerWaalsContact O-N 3.14Å; D375-R377 PolarHBondContact OD1-N 3.07Å; D375-H378 PolarHBondContact OD1-N 3.17Å; D375-H378 IonicContact OD1-ND1 2.74Å; D375-H378 IonicContact OD2-CE1 2.8Å; D375-H378 IonicContact OD2-CG 3.43Å; D375-H378 IonicContact OD2-ND1 3.48Å; D375-H378 PolarHBondContact OD2-ND1 3.19Å; D375-V418 HydrophobicContact CB-CG1 4.47Å
376K98.1Very high98.3Very high29 Ų2938.7 Ų38.713%0.12620%0.201CC..SBendtrans47.839.5-174.3-53.4-56.6171-1450112.1I372 L373 N374 V420 N422 W423 F424I372-K376 HydrophobicContact CG2-CD 3.82Å; L373-K376 PolarHBondContact O-N 3.3Å; L373-K376 VanDerWaalsContact O-N 3.09Å; L373-K376 PolarHBondContact O-NZ 3.08Å; N374-K376 PolarHBondContact O-N 3.14Å; K376-V420 HydrophobicContact CB-CB 4.07Å; K376-V420 HydrophobicContact CB-CG1 3.97Å; K376-V420 WeakPolarHBondContact CE-O 3.39Å; K376-V420 HydrophobicContact CG-CB 3.83Å; K376-V420 HydrophobicContact CG-CG1 4.1Å; K376-V420 WeakPolarHBondContact CG-O 3.44Å; K376-N422 WeakPolarHBondContact CD-OD1 3.38Å; K376-N422 WeakPolarHBondContact CE-OD1 3.41Å; K376-W423 PolarHBondContact O-NE1 3.42Å; K376-F424 HydrophobicContact CB-CE1 4.36Å; K376-F424 WeakPolarHBondContact O-CE1 3.47Å
377R97.8Very high98.3Very high22 Ų2240.5 Ų40.58%0.08321%0.209CC..SBendtrans-132.1-37172.6174.2170.5173-177.8-12.2111.2D375 D392 V393 L394 A452D375-R377 PolarHBondContact O-N 3.12Å; D375-R377 VanDerWaalsContact O-N 3.14Å; D375-R377 PolarHBondContact OD1-N 3.07Å; R377-D392 WeakPolarHBondContact CG-OD1 3.35Å; R377-D392 IonicContact CZ-OD1 2.74Å; R377-D392 IonicContact CZ-OD2 3.29Å; R377-D392 IonicContact NE-OD1 3.87Å; R377-D392 PolarHBondContact NE-OD1 2.9Å; R377-D392 VanDerWaalsContact NE-OD1 3.1Å; R377-D392 IonicContact NE-OD2 3.09Å; R377-D392 PolarHBondContact NE-OD2 3.37Å; R377-D392 IonicContact NH2-OD2 3.33Å; R377-D392 PolarHBondContact NH2-OD2 2.87Å; R377-V393 WeakPolarHBondContact O-CB 3.49Å; R377-V393 VanDerWaalsContact O-CG2 3.25Å; R377-V393 WeakPolarHBondContact O-CG2 3.31Å; R377-V393 PolarHBondContact O-N 3.32Å; R377-L394 HydrophobicContact CG-CB 4Å; R377-A452 PolarHBondContact NH1-O 2.83Å
378H98.4Very high98.3Very high30 Ų3040.1 Ų40.114%0.13921%0.207CC..EExtended strand (participates in β ladder)trans-104.3144.4-175.9-61.5105.7000111.8L373 D375 Y390 W391 D392L373-H378 WeakPolarHBondContact CB-O 3.36Å; L373-H378 HydrophobicContact CD1-CB 3.83Å; L373-H378 PolarHBondContact N-O 3.08Å; D375-H378 PolarHBondContact OD1-N 3.17Å; D375-H378 IonicContact OD1-ND1 2.74Å; D375-H378 IonicContact OD2-CE1 2.8Å; D375-H378 IonicContact OD2-CG 3.43Å; D375-H378 IonicContact OD2-ND1 3.48Å; D375-H378 PolarHBondContact OD2-ND1 3.19Å; H378-Y390 HydrophobicContact CB-CE1 4.36Å; H378-Y390 HydrophobicContact CB-CE2 3.69Å; H378-Y390 WeakPolarHBondContact CB-OH 3.35Å; H378-Y390 AromaticContact CD2-CE1 3.41Å; H378-Y390 VanDerWaalsContact CD2-CE1 3.41Å; H378-Y390 WeakPolarHBondContact CD2-CE1 3.46Å; H378-Y390 AromaticContact CD2-CZ 3.31Å; H378-Y390 PolarHBondContact CD2-OH 2.92Å; H378-Y390 PolarHBondContact CE1-OH 3.3Å; H378-Y390 AromaticContact CG-CZ 3.43Å; H378-Y390 VanDerWaalsContact CG-CZ 3.43Å; H378-Y390 PolarHBondContact ND1-OH 3.3Å; H378-Y390 AromaticContact NE2-CE1 3.98Å; H378-Y390 AromaticContact NE2-CZ 3.96Å; H378-Y390 PolarHBondContact NE2-OH 3.17Å; H378-W391 VanDerWaalsContact CA-O 3.24Å; H378-W391 WeakPolarHBondContact CA-O 3.5Å; H378-D392 IonicContact NE2-OD2 2.8Å
379I98.6Very high98.3Very high0 Ų036 Ų360%019%0.188CC..EExtended strand (participates in β ladder)trans-122.5141.7177.2-71177.3000109C370 H371 I372 T381 Y390 W391 V393 F424 V426 L433 I435C370-I379 WeakPolarHBondContact SG-CG2 3.16Å; H371-I379 WeakPolarHBondContact O-CA 3.23Å; I372-I379 HydrophobicContact CG1-CD1 4.37Å; I372-I379 HydrophobicContact CG1-CG1 4.17Å; I379-T381 HydrophobicContact CG2-CG2 3.61Å; I379-Y390 WeakPolarHBondContact O-CA 3.27Å; I379-W391 HydrophobicContact CB-CB 4.36Å; I379-W391 PolarHBondContact N-O 2.96Å; I379-W391 PolarHBondContact O-N 3.36Å; I379-V393 HydrophobicContact CB-CG2 4.34Å; I379-V393 HydrophobicContact CD1-CG2 3.27Å; I379-V393 HydrophobicContact CG1-CG2 3.5Å; I379-V393 VanDerWaalsContact CG1-CG2 3.5Å; I379-F424 HydrophobicContact CD1-CE2 4.05Å; I379-F424 HydrophobicContact CD1-CZ 4.46Å; I379-V426 HydrophobicContact CD1-CG2 3.73Å; I379-L433 HydrophobicContact CD1-CD2 4.42Å; I379-L433 HydrophobicContact CG2-CD2 4.35Å; I379-I435 HydrophobicContact CD1-CD1 4.13Å
380L98.7Very high98.3Very high0 Ų033.6 Ų33.60%018%0.175CC..EExtended strand (participates in β ladder)trans-105.6134.3163.5-153.574.9000109.2C370 H371 V388 A389 Y390 L402 F407 E410 I411C370-L380 CarbonylContact C-O 3.56Å; C370-L380 WeakPolarHBondContact CA-O 3.32Å; H371-L380 PolarHBondContact N-O 2.88Å; H371-L380 PolarHBondContact O-N 2.81Å; L380-V388 HydrophobicContact CD1-CG1 3.91Å; L380-V388 HydrophobicContact CD2-CG1 3.83Å; L380-V388 HydrophobicContact CG-CG1 3.66Å; L380-A389 WeakPolarHBondContact CA-O 3.28Å; L380-Y390 HydrophobicContact CD1-CD2 4.09Å; L380-L402 HydrophobicContact CD1-CD1 3.9Å; L380-F407 HydrophobicContact CB-CE2 4.05Å; L380-F407 HydrophobicContact CD2-CD2 3.93Å; L380-F407 HydrophobicContact CD2-CE2 3.83Å; L380-F407 HydrophobicContact CG-CD2 4.35Å; L380-F407 HydrophobicContact CG-CE2 3.9Å; L380-E410 HydrophobicContact CD1-CG 4.28Å; L380-E410 HydrophobicContact CD2-CB 3.9Å; L380-E410 HydrophobicContact CD2-CG 3.84Å; L380-I411 HydrophobicContact CD2-CG1 3.87Å
381T98.8Very high98.3Very high3 Ų332.7 Ų32.72%0.01817%0.166CC..EExtended strand (participates in β ladder)trans-125.3157176.667.50000112.4I367 Q369 C370 I379 V388 A389 W391 L433I367-T381 HydrophobicContact CD1-CG2 4.37Å; I367-T381 HydrophobicContact CG2-CG2 3.87Å; Q369-T381 VanDerWaalsContact O-CA 3.25Å; Q369-T381 WeakPolarHBondContact O-CA 3.23Å; Q369-T381 WeakPolarHBondContact O-CB 3.46Å; C370-T381 HydrophobicContact CB-CG2 4.44Å; I379-T381 HydrophobicContact CG2-CG2 3.61Å; T381-V388 WeakPolarHBondContact O-CA 3.46Å; T381-V388 WeakPolarHBondContact O-CG1 3.17Å; T381-A389 PolarHBondContact N-O 3.18Å; T381-A389 PolarHBondContact O-N 2.86Å; T381-W391 PolarHBondContact OG1-NE1 3.35Å; T381-L433 HydrophobicContact CG2-CD1 3.92Å; T381-L433 HydrophobicContact CG2-CD2 3.88Å; T381-L433 HydrophobicContact CG2-CG 4.16Å
382K98.8Very high98.3Very high35 Ų3530.2 Ų30.215%0.15215%0.154CC..EExtended strand (participates in β ladder)trans-124.3132.5168.3-164.9-176.3-169.9173.80109.5I368 Q369 N386 N387 V388 F407I368-K382 VanDerWaalsContact CG1-O 3.32Å; I368-K382 WeakPolarHBondContact CG1-O 3.41Å; I368-K382 PolarHBondContact N-O 3.06Å; Q369-K382 HydrophobicContact CB-CB 4.06Å; Q369-K382 PolarHBondContact N-O 2.8Å; Q369-K382 PolarHBondContact O-N 3.25Å; Q369-K382 VanDerWaalsContact OE1-CD 3.23Å; K382-N386 VanDerWaalsContact CE-OD1 3.26Å; K382-N386 WeakPolarHBondContact CE-OD1 3.33Å; K382-N387 WeakPolarHBondContact CA-O 3.44Å; K382-V388 HydrophobicContact CG-CG2 4.29Å; K382-F407 HydrophobicContact CB-CD2 3.95Å; K382-F407 HydrophobicContact CB-CE2 4.22Å; K382-F407 HydrophobicContact CB-CG 4.32Å; K382-F407 HydrophobicContact CD-CB 4.2Å
383D98.6Very high98.3Very high25 Ų2528 Ų2813%0.13414%0.143CC..EExtended strand (participates in β ladder)trans-98.1175.4179.777.910.1000113.6A365 S366 N385 N386 N387A365-D383 HydrophobicContact CB-CB 3.97Å; A365-D383 WeakPolarHBondContact CB-OD2 3.35Å; S366-D383 CarbonylContact O-C 3.21Å; S366-D383 WeakPolarHBondContact O-CA 3.36Å; S366-D383 WeakPolarHBondContact O-CB 3.48Å; D383-N385 PolarHBondContact O-N 2.74Å; D383-N385 VanDerWaalsContact O-N 3.17Å; D383-N385 VanDerWaalsContact OD1-C 3.27Å; D383-N385 VanDerWaalsContact OD1-CA 3.24Å; D383-N385 WeakPolarHBondContact OD1-CA 3.23Å; D383-N385 WeakPolarHBondContact OD1-CB 3.11Å; D383-N385 PolarHBondContact OD1-N 2.99Å; D383-N386 WeakPolarHBondContact O-CA 3.28Å; D383-N386 PolarHBondContact O-N 3.48Å; D383-N386 PolarHBondContact OD1-N 3.26Å; D383-N387 PolarHBondContact N-O 3.13Å; D383-N387 PolarHBondContact OD1-N 3.16Å; D383-N387 PolarHBondContact OD2-ND2 3.11Å
384T98.3Very high98.3Very high65 Ų6527.5 Ų27.540%0.39914%0.141SC..THydrogen-bonded Turntrans-63.7-14.7176.850.30000114.6A365 S366 I368 N386A365-T384 WeakPolarHBondContact CA-OG1 3.15Å; S366-T384 PolarHBondContact N-OG1 3.06Å; S366-T384 VanDerWaalsContact N-OG1 3.14Å; S366-T384 PolarHBondContact O-N 3.13Å; I368-T384 HydrophobicContact CG2-CG2 3.66Å; T384-N386 VanDerWaalsContact C-N 3.34Å
385N98Very high98.3Very high89 Ų8929.3 Ų29.348%0.47615%0.147SC..THydrogen-bonded Turntrans-93.93.9174.4-66.8-16.7000112D383 N387 K404D383-N385 PolarHBondContact O-N 2.74Å; D383-N385 VanDerWaalsContact O-N 3.17Å; D383-N385 VanDerWaalsContact OD1-C 3.27Å; D383-N385 VanDerWaalsContact OD1-CA 3.24Å; D383-N385 WeakPolarHBondContact OD1-CA 3.23Å; D383-N385 WeakPolarHBondContact OD1-CB 3.11Å; D383-N385 PolarHBondContact OD1-N 2.99Å; N385-N387 PolarHBondContact O-N 3.45Å; N385-K404 WeakPolarHBondContact O-CE 3.4Å
386N98.1Very high98.4Very high84 Ų8428 Ų2845%0.44914%0.14SC..  trans63.420.8-172.8-56.9-65.5000114.3K382 D383 T384K382-N386 VanDerWaalsContact CE-OD1 3.26Å; K382-N386 WeakPolarHBondContact CE-OD1 3.33Å; D383-N386 WeakPolarHBondContact O-CA 3.28Å; D383-N386 PolarHBondContact O-N 3.48Å; D383-N386 PolarHBondContact OD1-N 3.26Å; T384-N386 VanDerWaalsContact C-N 3.34Å
387N98.4Very high98.4Very high49 Ų4928.6 Ų28.626%0.26215%0.147SC..  trans-79.1137.1170.2-57-49.8000109.3K382 D383 N385 G403K382-N387 WeakPolarHBondContact CA-O 3.44Å; D383-N387 PolarHBondContact N-O 3.13Å; D383-N387 PolarHBondContact OD1-N 3.16Å; D383-N387 PolarHBondContact OD2-ND2 3.11Å; N385-N387 PolarHBondContact O-N 3.45Å; N387-G403 CarbonylContact C-O 3.55Å; N387-G403 WeakPolarHBondContact CA-O 3.25Å
388V98.8Very high98.4Very high0 Ų031.8 Ų31.80%016%0.162CC..EExtended strand (participates in β ladder)trans-101.1138.2174-178.70000109L380 T381 K382 L402 G403 V405 F407L380-V388 HydrophobicContact CD1-CG1 3.91Å; L380-V388 HydrophobicContact CD2-CG1 3.83Å; L380-V388 HydrophobicContact CG-CG1 3.66Å; T381-V388 WeakPolarHBondContact O-CA 3.46Å; T381-V388 WeakPolarHBondContact O-CG1 3.17Å; K382-V388 HydrophobicContact CG-CG2 4.29Å; V388-L402 HydrophobicContact CB-CB 4.34Å; V388-L402 HydrophobicContact CG1-CD1 4.08Å; V388-L402 WeakPolarHBondContact O-CA 3.4Å; V388-L402 WeakPolarHBondContact O-CB 3.48Å; V388-L402 PolarHBondContact O-N 2.78Å; V388-G403 PolarHBondContact N-O 2.82Å; V388-G403 PolarHBondContact O-N 2.8Å; V388-V405 HydrophobicContact CB-CG2 3.67Å; V388-V405 HydrophobicContact CG1-CG2 4.09Å; V388-V405 HydrophobicContact CG2-CG2 3.81Å; V388-V405 WeakPolarHBondContact CG2-O 3.41Å; V388-F407 HydrophobicContact CG1-CD2 4.05Å; V388-F407 HydrophobicContact CG2-CB 4.42Å; V388-F407 HydrophobicContact CG2-CD2 4.08Å
389A98.6Very high98.1Very high6 Ų633 Ų335%0.0518%0.182CC..EExtended strand (participates in β ladder)trans-137.6150.1177.600000111.2L380 T381 W391 K398 E400L380-A389 WeakPolarHBondContact CA-O 3.28Å; T381-A389 PolarHBondContact N-O 3.18Å; T381-A389 PolarHBondContact O-N 2.86Å; A389-W391 HydrophobicContact CB-CZ2 3.88Å; A389-W391 VanDerWaalsContact O-CD1 3.29Å; A389-W391 PolarHBondContact O-NE1 2.98Å; A389-K398 HydrophobicContact CB-CD 4.45Å; A389-E400 WeakPolarHBondContact CA-O 3.37Å
390Y98.5Very high97.9Very high37 Ų3736.9 Ų36.915%0.14520%0.2CC..EExtended strand (participates in β ladder)trans-109.5135.2178.7-178.9-96.8000110.2L373 H378 I379 L380 G399 E400L373-Y390 HydrophobicContact CD1-CD2 4.42Å; L373-Y390 HydrophobicContact CD1-CE2 3.67Å; H378-Y390 HydrophobicContact CB-CE1 4.36Å; H378-Y390 HydrophobicContact CB-CE2 3.69Å; H378-Y390 WeakPolarHBondContact CB-OH 3.35Å; H378-Y390 AromaticContact CD2-CE1 3.41Å; H378-Y390 VanDerWaalsContact CD2-CE1 3.41Å; H378-Y390 WeakPolarHBondContact CD2-CE1 3.46Å; H378-Y390 AromaticContact CD2-CZ 3.31Å; H378-Y390 PolarHBondContact CD2-OH 2.92Å; H378-Y390 PolarHBondContact CE1-OH 3.3Å; H378-Y390 AromaticContact CG-CZ 3.43Å; H378-Y390 VanDerWaalsContact CG-CZ 3.43Å; H378-Y390 PolarHBondContact ND1-OH 3.3Å; H378-Y390 AromaticContact NE2-CE1 3.98Å; H378-Y390 AromaticContact NE2-CZ 3.96Å; H378-Y390 PolarHBondContact NE2-OH 3.17Å; I379-Y390 WeakPolarHBondContact O-CA 3.27Å; L380-Y390 HydrophobicContact CD1-CD2 4.09Å; Y390-G399 WeakPolarHBondContact O-CA 3.49Å; Y390-G399 PolarHBondContact O-N 3.1Å; Y390-E400 HydrophobicContact CD1-CG 4.24Å; Y390-E400 HydrophobicContact CG-CG 4.26Å; Y390-E400 PolarHBondContact N-O 2.88Å; Y390-E400 PolarHBondContact O-N 3.1Å
391W98.7Very high97.9Very high22 Ų2241.8 Ų41.88%0.08323%0.226CC..EExtended strand (participates in β ladder)trans-132.1146.6-169.2-50.578.5000110.9I21 I367 H378 I379 T381 A389 K398 L433I21-W391 HydrophobicContact CG2-CE3 3.74Å; I21-W391 HydrophobicContact CG2-CZ3 3.88Å; I367-W391 HydrophobicContact CD1-CH2 4.46Å; I367-W391 HydrophobicContact CD1-CZ2 4.08Å; H378-W391 VanDerWaalsContact CA-O 3.24Å; H378-W391 WeakPolarHBondContact CA-O 3.5Å; I379-W391 HydrophobicContact CB-CB 4.36Å; I379-W391 PolarHBondContact N-O 2.96Å; I379-W391 PolarHBondContact O-N 3.36Å; T381-W391 PolarHBondContact OG1-NE1 3.35Å; A389-W391 HydrophobicContact CB-CZ2 3.88Å; A389-W391 VanDerWaalsContact O-CD1 3.29Å; A389-W391 PolarHBondContact O-NE1 2.98Å; W391-K398 HydrophobicContact CD2-CB 4.32Å; W391-K398 HydrophobicContact CD2-CG 4.05Å; W391-K398 HydrophobicContact CE3-CB 3.61Å; W391-K398 HydrophobicContact CE3-CG 3.81Å; W391-K398 HydrophobicContact CH2-CB 4.25Å; W391-K398 HydrophobicContact CH2-CD 4.23Å; W391-K398 HydrophobicContact CH2-CG 4.06Å; W391-K398 HydrophobicContact CZ2-CD 4.43Å; W391-K398 HydrophobicContact CZ2-CG 4.25Å; W391-K398 HydrophobicContact CZ3-CB 3.57Å; W391-K398 HydrophobicContact CZ3-CD 4.41Å; W391-K398 HydrophobicContact CZ3-CG 3.83Å; W391-L433 HydrophobicContact CB-CD1 4.24Å; W391-L433 HydrophobicContact CD2-CD1 3.54Å; W391-L433 HydrophobicContact CE3-CD1 3.89Å; W391-L433 HydrophobicContact CG-CD1 3.68Å; W391-L433 HydrophobicContact CZ2-CD1 4.45Å; W391-L433 HydrophobicContact CZ3-CD1 4.45Å
392D98.6Very high97.8Very high13 Ų1343.4 Ų43.47%0.0724%0.235CC..EExtended strand (participates in β ladder)trans-103.8109.9169.3-172.3-25000108.4R377 H378 L394 K395 A396 C397R377-D392 WeakPolarHBondContact CG-OD1 3.35Å; R377-D392 IonicContact CZ-OD1 2.74Å; R377-D392 IonicContact CZ-OD2 3.29Å; R377-D392 IonicContact NE-OD1 3.87Å; R377-D392 PolarHBondContact NE-OD1 2.9Å; R377-D392 VanDerWaalsContact NE-OD1 3.1Å; R377-D392 IonicContact NE-OD2 3.09Å; R377-D392 PolarHBondContact NE-OD2 3.37Å; R377-D392 IonicContact NH2-OD2 3.33Å; R377-D392 PolarHBondContact NH2-OD2 2.87Å; H378-D392 IonicContact NE2-OD2 2.8Å; D392-L394 WeakPolarHBondContact OD1-CB 3.45Å; D392-L394 PolarHBondContact OD1-N 3.42Å; D392-K395 HydrophobicContact CB-CB 4.19Å; D392-K395 PolarHBondContact OD1-N 3.26Å; D392-K395 VanDerWaalsContact OD1-N 3.08Å; D392-K395 WeakPolarHBondContact OD2-CD 3.24Å; D392-K395 WeakPolarHBondContact OD2-CG 2.85Å; D392-A396 WeakPolarHBondContact O-CA 3.46Å; D392-A396 PolarHBondContact O-N 2.98Å; D392-C397 PolarHBondContact N-O 3.43Å; D392-C397 PolarHBondContact O-N 2.87Å; D392-C397 VanDerWaalsContact O-N 3.11Å
393V98.6Very high97.7Very high0 Ų043 Ų430%024%0.241CC..THydrogen-bonded Turntrans-66.1-42-179.71770000110.5Y19 R377 I379 A396 W423 F424 I435Y19-V393 WeakPolarHBondContact OH-CG1 3.34Å; Y19-V393 PolarHBondContact OH-O 2.83Å; R377-V393 WeakPolarHBondContact O-CB 3.49Å; R377-V393 VanDerWaalsContact O-CG2 3.25Å; R377-V393 WeakPolarHBondContact O-CG2 3.31Å; R377-V393 PolarHBondContact O-N 3.32Å; I379-V393 HydrophobicContact CB-CG2 4.34Å; I379-V393 HydrophobicContact CD1-CG2 3.27Å; I379-V393 HydrophobicContact CG1-CG2 3.5Å; I379-V393 VanDerWaalsContact CG1-CG2 3.5Å; V393-A396 PolarHBondContact O-N 2.85Å; V393-A396 VanDerWaalsContact O-N 3.14Å; V393-W423 HydrophobicContact CG1-CH2 4.42Å; V393-F424 HydrophobicContact CB-CZ 4.34Å; V393-F424 HydrophobicContact CG1-CD1 4.28Å; V393-F424 HydrophobicContact CG1-CD2 4.27Å; V393-F424 HydrophobicContact CG1-CE1 4.11Å; V393-F424 HydrophobicContact CG1-CE2 4.11Å; V393-F424 HydrophobicContact CG1-CG 4.35Å; V393-F424 HydrophobicContact CG1-CZ 4.01Å; V393-F424 HydrophobicContact CG2-CE2 4.17Å; V393-F424 HydrophobicContact CG2-CZ 3.93Å; V393-I435 HydrophobicContact CG1-CD1 4.27Å; V393-I435 HydrophobicContact CG1-CG1 4.24Å; V393-I435 HydrophobicContact CG1-CG2 4.04Å
394L98.1Very high97.7Very high0 Ų049.6 Ų49.60%027%0.268CS..THydrogen-bonded Turntrans-65.8-42.8-176.2-175.166.7000110.8R377 D392 A396 W423 F454 L466 L470 F512R377-L394 HydrophobicContact CG-CB 4Å; D392-L394 WeakPolarHBondContact OD1-CB 3.45Å; D392-L394 PolarHBondContact OD1-N 3.42Å; L394-A396 VanDerWaalsContact C-N 3.28Å; L394-W423 HydrophobicContact CD1-CH2 4.16Å; L394-F454 HydrophobicContact CD2-CE2 4.08Å; L394-F454 HydrophobicContact CD2-CZ 4.1Å; L394-L466 HydrophobicContact CD1-CB 4.41Å; L394-L466 HydrophobicContact CD1-CD2 4.37Å; L394-L466 WeakPolarHBondContact CD1-O 3.16Å; L394-L466 HydrophobicContact CD2-CD2 3.91Å; L394-L470 HydrophobicContact CD1-CB 4.13Å; L394-L470 WeakPolarHBondContact O-CD1 3.3Å; L394-F512 HydrophobicContact CD1-CE1 3.76Å; L394-F512 HydrophobicContact CD1-CE2 4.39Å; L394-F512 HydrophobicContact CD1-CZ 3.46Å; L394-F512 VanDerWaalsContact CD1-CZ 3.46Å; L394-F512 HydrophobicContact CD2-CD1 4.31Å; L394-F512 HydrophobicContact CD2-CE1 3.78Å; L394-F512 HydrophobicContact CD2-CZ 4.25Å; L394-F512 HydrophobicContact CG-CD1 4.28Å; L394-F512 HydrophobicContact CG-CE1 3.54Å; L394-F512 HydrophobicContact CG-CE2 4.16Å; L394-F512 HydrophobicContact CG-CZ 3.48Å; L394-F512 VanDerWaalsContact CG-CZ 3.48Å; L394-F512 WeakPolarHBondContact O-CE2 3.38Å
395K98Very high97.7Very high76 Ų7649 Ų4933%0.3326%0.264SS..THydrogen-bonded Turntrans-84.5-1.1175.8-64.4-175.9177.9178.20113.8D392 C397 F512 P515D392-K395 HydrophobicContact CB-CB 4.19Å; D392-K395 PolarHBondContact OD1-N 3.26Å; D392-K395 VanDerWaalsContact OD1-N 3.08Å; D392-K395 WeakPolarHBondContact OD2-CD 3.24Å; D392-K395 WeakPolarHBondContact OD2-CG 2.85Å; K395-C397 VanDerWaalsContact C-N 3.27Å; K395-C397 PolarHBondContact O-N 3.05Å; K395-F512 HydrophobicContact CG-CB 4.23Å; K395-F512 HydrophobicContact CG-CD2 4.29Å; K395-F512 HydrophobicContact CG-CG 4.29Å; K395-P515 WeakPolarHBondContact O-CD 3.12Å
396A98.3Very high97.7Very high2 Ų250.9 Ų50.92%0.01727%0.27CS..THydrogen-bonded Turntrans5141.6-178.600000113.7Y19 I21 D392 V393 L394 V514Y19-A396 HydrophobicContact CD2-CB 3.97Å; Y19-A396 HydrophobicContact CE2-CB 3.53Å; I21-A396 HydrophobicContact CG1-CB 4.24Å; D392-A396 WeakPolarHBondContact O-CA 3.46Å; D392-A396 PolarHBondContact O-N 2.98Å; V393-A396 PolarHBondContact O-N 2.85Å; V393-A396 VanDerWaalsContact O-N 3.14Å; L394-A396 VanDerWaalsContact C-N 3.28Å; A396-V514 HydrophobicContact CB-CB 4.15Å; A396-V514 HydrophobicContact CB-CG1 3.87Å
397C97.6Very high97.7Very high42 Ų4247.4 Ų47.428%0.28425%0.251SS..EExtended strand (participates in β ladder)trans-140.3159.7-174.568.30000113.3D392 K395 P515D392-C397 PolarHBondContact N-O 3.43Å; D392-C397 PolarHBondContact O-N 2.87Å; D392-C397 VanDerWaalsContact O-N 3.11Å; K395-C397 VanDerWaalsContact C-N 3.27Å; K395-C397 PolarHBondContact O-N 3.05Å; C397-P515 HydrophobicContact CB-CG 4.45Å
398K97.1Very high97.6Very high90 Ų9050.3 Ų50.339%0.39127%0.266SS..EExtended strand (participates in β ladder)trans-77132.5169.2-164.5-169.8-69-170.70109.1A389 W391 D401A389-K398 HydrophobicContact CB-CD 4.45Å; W391-K398 HydrophobicContact CD2-CB 4.32Å; W391-K398 HydrophobicContact CD2-CG 4.05Å; W391-K398 HydrophobicContact CE3-CB 3.61Å; W391-K398 HydrophobicContact CE3-CG 3.81Å; W391-K398 HydrophobicContact CH2-CB 4.25Å; W391-K398 HydrophobicContact CH2-CD 4.23Å; W391-K398 HydrophobicContact CH2-CG 4.06Å; W391-K398 HydrophobicContact CZ2-CD 4.43Å; W391-K398 HydrophobicContact CZ2-CG 4.25Å; W391-K398 HydrophobicContact CZ3-CB 3.57Å; W391-K398 HydrophobicContact CZ3-CD 4.41Å; W391-K398 HydrophobicContact CZ3-CG 3.83Å; K398-D401 WeakPolarHBondContact CD-OD1 3.11Å; K398-D401 WeakPolarHBondContact CD-OD2 3.36Å; K398-D401 IonicContact NZ-OD1 3.9Å; K398-D401 PolarHBondContact NZ-OD1 2.91Å; K398-D401 IonicContact NZ-OD2 3.4Å; K398-D401 PolarHBondContact NZ-OD2 3.32Å
399G93.3Very high97.6Very high54 Ų5456.7 Ų56.756%0.55730%0.296SS*.EExtended strand (participates in β ladder)trans-85.8-68.7173.100000111.7Y390Y390-G399 WeakPolarHBondContact O-CA 3.49Å; Y390-G399 PolarHBondContact O-N 3.1Å
400E95.2Very high97.5Very high82 Ų8257.1 Ų57.138%0.38330%0.297SS..EExtended strand (participates in β ladder)trans-140.8143.5-176.455.4-179.3166.200111.8A389 Y390 L402 R414A389-E400 WeakPolarHBondContact CA-O 3.37Å; Y390-E400 HydrophobicContact CD1-CG 4.24Å; Y390-E400 HydrophobicContact CG-CG 4.26Å; Y390-E400 PolarHBondContact N-O 2.88Å; Y390-E400 PolarHBondContact O-N 3.1Å; E400-L402 HydrophobicContact CG-CD2 3.8Å; E400-L402 HydrophobicContact CG-CG 4.38Å; E400-R414 IonicContact OE1-CZ 2.92Å; E400-R414 IonicContact OE1-NH1 3.55Å; E400-R414 PolarHBondContact OE1-NH1 2.8Å; E400-R414 IonicContact OE1-NH2 3.98Å; E400-R414 PolarHBondContact OE1-NH2 2.96Å
401D97.1Very high97.5Very high104 Ų10456.6 Ų56.656%0.55630%0.297SS*.EExtended strand (participates in β ladder)trans-93.4115.4168.8-77.8-61.6000108.5K398K398-D401 WeakPolarHBondContact CD-OD1 3.11Å; K398-D401 WeakPolarHBondContact CD-OD2 3.36Å; K398-D401 IonicContact NZ-OD1 3.9Å; K398-D401 PolarHBondContact NZ-OD1 2.91Å; K398-D401 IonicContact NZ-OD2 3.4Å; K398-D401 PolarHBondContact NZ-OD2 3.32Å
402L97.7Very high97.5Very high37 Ų3763 Ų6319%0.19433%0.325CS..EExtended strand (participates in β ladder)trans-88.7-7.3-176.3-57.6178.5000112.6L380 V388 E400 V405 E410L380-L402 HydrophobicContact CD1-CD1 3.9Å; V388-L402 HydrophobicContact CB-CB 4.34Å; V388-L402 HydrophobicContact CG1-CD1 4.08Å; V388-L402 WeakPolarHBondContact O-CA 3.4Å; V388-L402 WeakPolarHBondContact O-CB 3.48Å; V388-L402 PolarHBondContact O-N 2.78Å; E400-L402 HydrophobicContact CG-CD2 3.8Å; E400-L402 HydrophobicContact CG-CG 4.38Å; L402-V405 HydrophobicContact CB-CG2 3.9Å; L402-V405 WeakPolarHBondContact O-CG1 3.21Å; L402-E410 HydrophobicContact CD1-CG 3.62Å
403G97.4Very high97.4Very high27 Ų2769.8 Ų69.828%0.27835%0.354SS..EExtended strand (participates in β ladder)trans68.8-150.5-176.500000112N387 V388 V405N387-G403 CarbonylContact C-O 3.55Å; N387-G403 WeakPolarHBondContact CA-O 3.25Å; V388-G403 PolarHBondContact N-O 2.82Å; V388-G403 PolarHBondContact O-N 2.8Å; G403-V405 PolarHBondContact O-N 3.23Å; G403-V405 VanDerWaalsContact O-N 3.09Å
404K97.8Very high97.3Very high162 Ų16272.3 Ų72.370%0.70436%0.364SS*.SBendtrans-88.171.6-174.1-62.7-179.7-179.3177.30111.5N385N385-K404 WeakPolarHBondContact O-CE 3.4Å
405V97.7Very high97.2Very high52 Ų5277.9 Ų77.932%0.31539%0.388SS..  trans-99.3160.4172.6-63.60000111.3V388 L402 G403 F407 E410V388-V405 HydrophobicContact CB-CG2 3.67Å; V388-V405 HydrophobicContact CG1-CG2 4.09Å; V388-V405 HydrophobicContact CG2-CG2 3.81Å; V388-V405 WeakPolarHBondContact CG2-O 3.41Å; L402-V405 HydrophobicContact CB-CG2 3.9Å; L402-V405 WeakPolarHBondContact O-CG1 3.21Å; G403-V405 PolarHBondContact O-N 3.23Å; G403-V405 VanDerWaalsContact O-N 3.09Å; V405-F407 PolarHBondContact O-N 3.32Å; V405-E410 HydrophobicContact CG2-CB 4.41Å
406E97.8Very high97Very high129 Ų12980.5 Ų80.560%0.60340%0.399SS*.  trans-70.5119.6174.8-74.9-56.1143.200111D408 E409 E410E406-D408 PolarHBondContact O-N 2.91Å; E406-E409 HydrophobicContact CB-CB 4.12Å; E406-E409 HydrophobicContact CB-CG 3.99Å; E406-E409 PolarHBondContact O-N 2.97Å; E406-E410 PolarHBondContact O-N 3.49Å; E406-E410 VanDerWaalsContact O-N 3.08Å
407F98Very high96.8Very high12 Ų1284.5 Ų84.55%0.05342%0.419CS..Hα-helixtrans-63.7-45.3-168.2-175.4-113.4000112.6Q369 H371 L380 K382 V388 V405 E410 I411Q369-F407 HydrophobicContact CB-CE1 4.06Å; Q369-F407 HydrophobicContact CB-CZ 4.23Å; H371-F407 HydrophobicContact CB-CE1 4.3Å; H371-F407 HydrophobicContact CB-CZ 3.9Å; L380-F407 HydrophobicContact CB-CE2 4.05Å; L380-F407 HydrophobicContact CD2-CD2 3.93Å; L380-F407 HydrophobicContact CD2-CE2 3.83Å; L380-F407 HydrophobicContact CG-CD2 4.35Å; L380-F407 HydrophobicContact CG-CE2 3.9Å; K382-F407 HydrophobicContact CB-CD2 3.95Å; K382-F407 HydrophobicContact CB-CE2 4.22Å; K382-F407 HydrophobicContact CB-CG 4.32Å; K382-F407 HydrophobicContact CD-CB 4.2Å; V388-F407 HydrophobicContact CG1-CD2 4.05Å; V388-F407 HydrophobicContact CG2-CB 4.42Å; V388-F407 HydrophobicContact CG2-CD2 4.08Å; V405-F407 PolarHBondContact O-N 3.32Å; F407-E410 PolarHBondContact O-N 3.41Å; F407-I411 HydrophobicContact CD1-CD1 3.83Å; F407-I411 HydrophobicContact CE1-CD1 3.59Å; F407-I411 HydrophobicContact CG-CD1 4.44Å; F407-I411 HydrophobicContact CZ-CD1 3.98Å; F407-I411 WeakPolarHBondContact O-CG1 3.3Å; F407-I411 PolarHBondContact O-N 2.8Å; F407-I411 VanDerWaalsContact O-N 3.09Å
408D97.9Very high96.6Very high109 Ų10984.5 Ų84.558%0.58342%0.418SS*.Hα-helixtrans-72.1-29.6-178.5-65.9-36.8000112.7E406 K412E406-D408 PolarHBondContact O-N 2.91Å; D408-K412 WeakPolarHBondContact O-CG 3.48Å; D408-K412 PolarHBondContact O-N 3.06Å
409E97.5Very high96.6Very high134 Ų13483.6 Ų83.663%0.62641%0.412SS*.Hα-helixtrans-70.8-41.5174.9-64.8-167.9157.300111.2E406 I411 K412 K413E406-E409 HydrophobicContact CB-CB 4.12Å; E406-E409 HydrophobicContact CB-CG 3.99Å; E406-E409 PolarHBondContact O-N 2.97Å; E409-I411 VanDerWaalsContact C-N 3.32Å; E409-I411 PolarHBondContact O-N 3.21Å; E409-K412 PolarHBondContact O-N 3.38Å; E409-K413 WeakPolarHBondContact O-CB 3.4Å; E409-K413 PolarHBondContact O-N 3.08Å
410E97.9Very high96.7Very high15 Ų1581.2 Ų81.27%0.0739%0.387CS..Hα-helixtrans-67.9-33.1177.6-169.164.2-158.200111.8L380 L402 V405 E406 F407 K413 R414L380-E410 HydrophobicContact CD1-CG 4.28Å; L380-E410 HydrophobicContact CD2-CB 3.9Å; L380-E410 HydrophobicContact CD2-CG 3.84Å; L402-E410 HydrophobicContact CD1-CG 3.62Å; V405-E410 HydrophobicContact CG2-CB 4.41Å; E406-E410 PolarHBondContact O-N 3.49Å; E406-E410 VanDerWaalsContact O-N 3.08Å; F407-E410 PolarHBondContact O-N 3.41Å; E410-K413 PolarHBondContact O-N 3.29Å; E410-K413 IonicContact OE1-NZ 2.7Å; E410-K413 WeakPolarHBondContact OE2-CD 3.45Å; E410-K413 IonicContact OE2-NZ 2.74Å; E410-K413 PolarHBondContact OE2-NZ 2.8Å; E410-R414 WeakPolarHBondContact O-CG 3.46Å; E410-R414 PolarHBondContact O-N 2.83Å; E410-R414 VanDerWaalsContact O-N 3.15Å; E410-R414 IonicContact OE1-CZ 3.19Å; E410-R414 VanDerWaalsContact OE1-CZ 3.25Å; E410-R414 IonicContact OE1-NE 3.19Å; E410-R414 PolarHBondContact OE1-NE 2.84Å; E410-R414 IonicContact OE1-NH2 3.2Å; E410-R414 PolarHBondContact OE1-NH2 3.24Å
411I97.9Very high96.8Very high26 Ų2678.3 Ų78.313%0.13338%0.375CS..Hα-helixtrans-59.7-50.1169.3-70.7165.5000110.7H371 L380 F407 E409 K413 R414 F415H371-I411 HydrophobicContact CB-CD1 3.62Å; H371-I411 HydrophobicContact CB-CG1 4.06Å; H371-I411 WeakPolarHBondContact NE2-CG2 3.31Å; L380-I411 HydrophobicContact CD2-CG1 3.87Å; F407-I411 HydrophobicContact CD1-CD1 3.83Å; F407-I411 HydrophobicContact CE1-CD1 3.59Å; F407-I411 HydrophobicContact CG-CD1 4.44Å; F407-I411 HydrophobicContact CZ-CD1 3.98Å; F407-I411 WeakPolarHBondContact O-CG1 3.3Å; F407-I411 PolarHBondContact O-N 2.8Å; F407-I411 VanDerWaalsContact O-N 3.09Å; E409-I411 VanDerWaalsContact C-N 3.32Å; E409-I411 PolarHBondContact O-N 3.21Å; I411-K413 VanDerWaalsContact C-N 3.35Å; I411-K413 PolarHBondContact O-N 3.47Å; I411-R414 PolarHBondContact O-N 2.75Å; I411-F415 PolarHBondContact O-N 3.36Å
412K97.6Very high96.8Very high158 Ų15877.5 Ų77.569%0.68737%0.371SS*.Hα-helixtrans-61.9-42.7179.9-71.9170.7-174.8172.80111.7D408 E409 R414 F415D408-K412 WeakPolarHBondContact O-CG 3.48Å; D408-K412 PolarHBondContact O-N 3.06Å; E409-K412 PolarHBondContact O-N 3.38Å; K412-R414 PolarHBondContact O-N 3.19Å; K412-F415 VanDerWaalsContact O-CB 3.24Å; K412-F415 WeakPolarHBondContact O-CB 3.33Å; K412-F415 PolarHBondContact O-N 2.94Å; K412-F415 VanDerWaalsContact O-N 3.15Å
413K97.6Very high96.8Very high154 Ų15475.8 Ų75.867%0.6736%0.362SS*.Hα-helixtrans-59.8-33.2177.9-177.7-174170-1650112.7E409 E410 I411E409-K413 WeakPolarHBondContact O-CB 3.4Å; E409-K413 PolarHBondContact O-N 3.08Å; E410-K413 PolarHBondContact O-N 3.29Å; E410-K413 IonicContact OE1-NZ 2.7Å; E410-K413 WeakPolarHBondContact OE2-CD 3.45Å; E410-K413 IonicContact OE2-NZ 2.74Å; E410-K413 PolarHBondContact OE2-NZ 2.8Å; I411-K413 VanDerWaalsContact C-N 3.35Å; I411-K413 PolarHBondContact O-N 3.47Å
414R96.5Very high96.9Very high54 Ų5474.9 Ų74.920%0.20435%0.35CS..THydrogen-bonded Turntrans-95.47.4179.8-65-176.8-175.5-107.2-10.1113.9L373 E400 E410 I411 K412 K416L373-R414 HydrophobicContact CD1-CB 4.31Å; L373-R414 HydrophobicContact CD2-CB 4.3Å; E400-R414 IonicContact OE1-CZ 2.92Å; E400-R414 IonicContact OE1-NH1 3.55Å; E400-R414 PolarHBondContact OE1-NH1 2.8Å; E400-R414 IonicContact OE1-NH2 3.98Å; E400-R414 PolarHBondContact OE1-NH2 2.96Å; E410-R414 WeakPolarHBondContact O-CG 3.46Å; E410-R414 PolarHBondContact O-N 2.83Å; E410-R414 VanDerWaalsContact O-N 3.15Å; E410-R414 IonicContact OE1-CZ 3.19Å; E410-R414 VanDerWaalsContact OE1-CZ 3.25Å; E410-R414 IonicContact OE1-NE 3.19Å; E410-R414 PolarHBondContact OE1-NE 2.84Å; E410-R414 IonicContact OE1-NH2 3.2Å; E410-R414 PolarHBondContact OE1-NH2 3.24Å; I411-R414 PolarHBondContact O-N 2.75Å; K412-R414 PolarHBondContact O-N 3.19Å; R414-K416 PolarHBondContact O-N 2.99Å
415F96Very high96.9Very high117 Ų11770 Ų7051%0.51334%0.336SS..  trans-61.1127.2177.1178.5-92.3000110.4N374 I411 K412 M417 F665N374-F415 WeakPolarHBondContact ND2-CD2 3.25Å; N374-F415 WeakPolarHBondContact ND2-CE2 3.32Å; I411-F415 PolarHBondContact O-N 3.36Å; K412-F415 VanDerWaalsContact O-CB 3.24Å; K412-F415 WeakPolarHBondContact O-CB 3.33Å; K412-F415 PolarHBondContact O-N 2.94Å; K412-F415 VanDerWaalsContact O-N 3.15Å; F415-M417 HydrophobicContact CE1-CB 4.03Å; F415-M417 HydrophobicContact CZ-CB 4.46Å; F415-F665 HydrophobicContact CE2-CE1 4.36Å; F415-F665 HydrophobicContact CZ-CE1 4.02Å; F415-F665 HydrophobicContact CZ-CZ 4.39Å
416K93.8Very high96.9Very high130 Ų13069.4 Ų69.457%0.56533%0.333SS*.  trans-121.8133.1169.9-65.9-179.6-178.3177.90108.2N374 R414 V418N374-K416 WeakPolarHBondContact CB-O 3.44Å; N374-K416 PolarHBondContact ND2-O 2.79Å; R414-K416 PolarHBondContact O-N 2.99Å; K416-V418 HydrophobicContact CB-CG1 4.09Å; K416-V418 PolarHBondContact O-N 3.06Å
417M93.5Very high96.9Very high86 Ų8665.2 Ų65.242%0.42431%0.314SS..  trans-80.465.1178.6-164.7174.9-179.900110.6F415 M657 T661 F665 I666F415-M417 HydrophobicContact CE1-CB 4.03Å; F415-M417 HydrophobicContact CZ-CB 4.46Å; M417-M657 HydrophobicContact CB-CE 4.39Å; M417-M657 HydrophobicContact CE-CE 3.76Å; M417-M657 HydrophobicContact CG-CE 3.71Å; M417-M657 HydrophobicContact SD-CE 3.55Å; M417-M657 VanDerWaalsContact SD-CE 3.55Å; M417-T661 WeakPolarHBondContact O-CG2 3.4Å; M417-F665 HydrophobicContact CE-CB 3.55Å; M417-F665 HydrophobicContact CE-CD1 4.43Å; M417-F665 HydrophobicContact CE-CG 4Å; M417-F665 HydrophobicContact CG-CD1 4.45Å; M417-F665 HydrophobicContact CG-CD2 4.19Å; M417-F665 HydrophobicContact CG-CE2 4.43Å; M417-F665 HydrophobicContact CG-CG 4.19Å; M417-I666 HydrophobicContact CE-CG1 4.32Å
418V94.5Very high97Very high43 Ų4366.8 Ų66.826%0.26132%0.323SS..  trans-126.8146.9176.463.70000108.3N374 D375 K416 V420 F665N374-V418 HydrophobicContact CB-CG1 4.09Å; N374-V418 WeakPolarHBondContact CB-O 3.45Å; D375-V418 HydrophobicContact CB-CG1 4.47Å; K416-V418 HydrophobicContact CB-CG1 4.09Å; K416-V418 PolarHBondContact O-N 3.06Å; V418-V420 HydrophobicContact CG2-CG2 4.4Å; V418-F665 WeakPolarHBondContact O-CE2 3.34Å
419Y95.4Very high96.9Very high71 Ų7165.2 Ų65.228%0.27831%0.311SS..  trans-119.7117.5172.6177.3-103000110.7P421 R660 T661 H664Y419-P421 HydrophobicContact CE1-CG 4.35Å; Y419-R660 HydrophobicContact CD1-CB 3.96Å; Y419-R660 HydrophobicContact CD1-CG 4.09Å; Y419-R660 WeakPolarHBondContact O-CD 3.26Å; Y419-R660 PolarHBondContact O-NE 3.4Å; Y419-T661 PolarHBondContact N-OG1 3.41Å; Y419-H664 HydrophobicContact CD1-CB 4.02Å; Y419-H664 HydrophobicContact CD2-CB 3.77Å; Y419-H664 AromaticContact CD2-CD2 3.46Å; Y419-H664 VanDerWaalsContact CD2-CD2 3.46Å; Y419-H664 WeakPolarHBondContact CD2-CD2 3.5Å; Y419-H664 AromaticContact CD2-CE1 3.61Å; Y419-H664 AromaticContact CD2-CG 3.24Å; Y419-H664 AromaticContact CD2-ND1 3.35Å; Y419-H664 VanDerWaalsContact CD2-ND1 3.35Å; Y419-H664 WeakPolarHBondContact CD2-ND1 3.37Å; Y419-H664 AromaticContact CD2-NE2 3.69Å; Y419-H664 HydrophobicContact CE2-CB 4.31Å; Y419-H664 AromaticContact CE2-CE1 3.41Å; Y419-H664 VanDerWaalsContact CE2-CE1 3.41Å; Y419-H664 WeakPolarHBondContact CE2-CE1 3.47Å; Y419-H664 AromaticContact CE2-CG 3.64Å; Y419-H664 AromaticContact CE2-ND1 3.19Å; Y419-H664 WeakPolarHBondContact CE2-ND1 3.49Å; Y419-H664 AromaticContact CE2-NE2 3.96Å; Y419-H664 HydrophobicContact CG-CB 3.59Å; Y419-H664 AromaticContact CG-CG 3.64Å; Y419-H664 AromaticContact CZ-ND1 3.81Å
420V96.8Very high97Very high4 Ų459 Ų592%0.02428%0.282CS..  trans-113.7133168.5-178.10000108.2N374 K376 V418 A445 V447N374-V420 PolarHBondContact O-N 3.28Å; K376-V420 HydrophobicContact CB-CB 4.07Å; K376-V420 HydrophobicContact CB-CG1 3.97Å; K376-V420 WeakPolarHBondContact CE-O 3.39Å; K376-V420 HydrophobicContact CG-CB 3.83Å; K376-V420 HydrophobicContact CG-CG1 4.1Å; K376-V420 WeakPolarHBondContact CG-O 3.44Å; V418-V420 HydrophobicContact CG2-CG2 4.4Å; V420-A445 HydrophobicContact CG1-CB 3.71Å; V420-V447 HydrophobicContact CG1-CG1 4.19Å; V420-V447 HydrophobicContact CG2-CG1 4.09Å
421P96.3Very high97Very high20 Ų2058.3 Ų58.313%0.1328%0.279CS..  trans-56.2144.5174-25.735.5000112Y419 A444Y419-P421 HydrophobicContact CE1-CG 4.35Å; P421-A444 HydrophobicContact CB-CB 3.91Å
422N97.3Very high97Very high88 Ų8857.2 Ų57.247%0.47127%0.274SS..  trans-61.8140.2170.8-76.7-24.7000110K376K376-N422 WeakPolarHBondContact CD-OD1 3.38Å; K376-N422 WeakPolarHBondContact CE-OD1 3.41Å
423W98.1Very high97.1Very high0 Ų049.7 Ų49.70%024%0.241CC..  trans-142.14.5-179.963.9-82.9000113.3K376 V393 L394 L437 D441 C442 A445 L466 L470K376-W423 PolarHBondContact O-NE1 3.42Å; V393-W423 HydrophobicContact CG1-CH2 4.42Å; L394-W423 HydrophobicContact CD1-CH2 4.16Å; W423-L437 HydrophobicContact CE3-CD2 3.96Å; W423-L437 HydrophobicContact CZ3-CD2 3.85Å; W423-D441 VanDerWaalsContact CA-O 3.31Å; W423-D441 WeakPolarHBondContact CA-O 3.49Å; W423-D441 WeakPolarHBondContact CB-O 3.41Å; W423-C442 WeakPolarHBondContact O-CA 3.18Å; W423-A445 HydrophobicContact CB-CB 3.85Å; W423-A445 HydrophobicContact CG-CB 3.63Å; W423-L466 HydrophobicContact CD2-CB 4.08Å; W423-L466 HydrophobicContact CE3-CB 4.44Å; W423-L466 HydrophobicContact CH2-CB 4.22Å; W423-L466 HydrophobicContact CZ2-CB 3.83Å; W423-L466 HydrophobicContact CZ2-CD1 4.18Å; W423-L466 HydrophobicContact CZ3-CB 4.5Å; W423-L470 HydrophobicContact CH2-CB 4.46Å; W423-L470 HydrophobicContact CH2-CD2 3.77Å; W423-L470 HydrophobicContact CZ3-CB 4.24Å; W423-L470 HydrophobicContact CZ3-CD2 3.58Å
424F98.6Very high97.1Very high8 Ų842.8 Ų42.84%0.03521%0.211CC..  trans-152.5162.3174.666.8-87.4000109.8I372 K376 I379 V393 V426 I435 T436 L437I372-F424 HydrophobicContact CD1-CE2 3.81Å; I372-F424 HydrophobicContact CD1-CZ 4.22Å; I372-F424 HydrophobicContact CG1-CE2 4.21Å; I372-F424 HydrophobicContact CG1-CZ 4.4Å; I372-F424 HydrophobicContact CG2-CE2 4.35Å; I372-F424 HydrophobicContact CG2-CZ 3.71Å; K376-F424 HydrophobicContact CB-CE1 4.36Å; K376-F424 WeakPolarHBondContact O-CE1 3.47Å; I379-F424 HydrophobicContact CD1-CE2 4.05Å; I379-F424 HydrophobicContact CD1-CZ 4.46Å; V393-F424 HydrophobicContact CB-CZ 4.34Å; V393-F424 HydrophobicContact CG1-CD1 4.28Å; V393-F424 HydrophobicContact CG1-CD2 4.27Å; V393-F424 HydrophobicContact CG1-CE1 4.11Å; V393-F424 HydrophobicContact CG1-CE2 4.11Å; V393-F424 HydrophobicContact CG1-CG 4.35Å; V393-F424 HydrophobicContact CG1-CZ 4.01Å; V393-F424 HydrophobicContact CG2-CE2 4.17Å; V393-F424 HydrophobicContact CG2-CZ 3.93Å; F424-V426 HydrophobicContact CD2-CG2 3.81Å; F424-V426 HydrophobicContact CE2-CG2 3.54Å; F424-I435 HydrophobicContact CB-CG2 3.82Å; F424-I435 HydrophobicContact CD2-CD1 4.46Å; F424-I435 HydrophobicContact CD2-CG2 3.83Å; F424-I435 HydrophobicContact CG-CG2 4.03Å; F424-T436 WeakPolarHBondContact CA-O 3.41Å; F424-L437 HydrophobicContact CB-CD2 3.83Å
425S98.4Very high97.2Very high60 Ų6040.2 Ų40.242%0.4220%0.202SC..EExtended strand (participates in β ladder)trans-119.1158.5168.858.60000110.6I435 T436S425-I435 WeakPolarHBondContact O-CA 3.45Å; S425-T436 PolarHBondContact N-O 3.37Å; S425-T436 PolarHBondContact O-N 3.22Å; S425-T436 PolarHBondContact OG-O 2.84Å
426V98.6Very high97.4Very high40 Ų4035.3 Ų35.324%0.24218%0.181CC..EExtended strand (participates in β ladder)trans-123.6133.6-178.5-1740000109.1I372 I379 F424 L428 L433 T434 I435I372-V426 HydrophobicContact CD1-CG2 3.88Å; I372-V426 HydrophobicContact CG1-CG2 4.21Å; I379-V426 HydrophobicContact CD1-CG2 3.73Å; F424-V426 HydrophobicContact CD2-CG2 3.81Å; F424-V426 HydrophobicContact CE2-CG2 3.54Å; V426-L428 HydrophobicContact CG1-CD2 4.26Å; V426-L433 HydrophobicContact CG1-CD2 3.71Å; V426-T434 WeakPolarHBondContact CA-O 3.38Å; V426-I435 HydrophobicContact CB-CD1 4.44Å; V426-I435 HydrophobicContact CG1-CD1 4.2Å; V426-I435 HydrophobicContact CG2-CD1 3.79Å
427D97.4Very high97.6Very high40 Ų4029.1 Ų29.121%0.21415%0.154CC..EExtended strand (participates in β ladder)trans-123147.4167.787.478000111.5K429 T434D427-K429 VanDerWaalsContact OD1-CD 3.27Å; D427-K429 WeakPolarHBondContact OD1-CD 3.44Å; D427-K429 WeakPolarHBondContact OD1-CE 3.26Å; D427-K429 WeakPolarHBondContact OD1-CG 3.37Å; D427-K429 PolarHBondContact OD1-N 2.91Å; D427-T434 PolarHBondContact N-O 2.98Å; D427-T434 PolarHBondContact O-N 3.34Å; D427-T434 VanDerWaalsContact O-N 3.13Å; D427-T434 VanDerWaalsContact OD2-CB 3.24Å; D427-T434 WeakPolarHBondContact OD2-CB 3.39Å; D427-T434 VanDerWaalsContact OD2-CG2 3.28Å; D427-T434 WeakPolarHBondContact OD2-CG2 3.31Å
428L98.5Very high97.7Very high45 Ų4526.2 Ų26.224%0.23614%0.141CC..  trans-115.616.8-178.2-58.4-177.4000111.9I367 C370 V426 T430 G431 L433I367-L428 HydrophobicContact CB-CD2 4.27Å; I367-L428 HydrophobicContact CG2-CD1 3.98Å; I367-L428 HydrophobicContact CG2-CD2 3.68Å; I367-L428 HydrophobicContact CG2-CG 4.44Å; C370-L428 HydrophobicContact CB-CD1 3.97Å; C370-L428 HydrophobicContact CB-CD2 4.32Å; C370-L428 HydrophobicContact CB-CG 4.48Å; V426-L428 HydrophobicContact CG1-CD2 4.26Å; L428-T430 PolarHBondContact O-N 2.87Å; L428-G431 PolarHBondContact O-N 2.99Å; L428-L433 HydrophobicContact CD2-CD2 3.89Å
429K97.5Very high97.8Very high76 Ų7628.2 Ų28.233%0.3315%0.147SC..THydrogen-bonded Turntrans-61.6-33.6-170.174.3-159.2168.8169.70111.6N31 D76 W77 D427 G431N31-K429 PolarHBondContact ND2-O 2.85Å; D76-K429 WeakPolarHBondContact OD2-CD 3.43Å; D76-K429 WeakPolarHBondContact OD2-CE 3.32Å; D76-K429 IonicContact OD2-NZ 3.47Å; D76-K429 PolarHBondContact OD2-NZ 3.01Å; W77-K429 PolarHBondContact NE1-O 2.89Å; D427-K429 VanDerWaalsContact OD1-CD 3.27Å; D427-K429 WeakPolarHBondContact OD1-CD 3.44Å; D427-K429 WeakPolarHBondContact OD1-CE 3.26Å; D427-K429 WeakPolarHBondContact OD1-CG 3.37Å; D427-K429 PolarHBondContact OD1-N 2.91Å; K429-G431 VanDerWaalsContact C-N 3.3Å; K429-G431 PolarHBondContact O-N 3.26Å
430T98.3Very high97.7Very high4 Ų429.2 Ų29.23%0.02517%0.165CC..THydrogen-bonded Turntrans-83.3-4178.658.20000113.3D51 L428 M432D51-T430 VanDerWaalsContact CA-O 3.28Å; D51-T430 WeakPolarHBondContact CA-O 3.37Å; D51-T430 WeakPolarHBondContact CB-O 3.37Å; L428-T430 PolarHBondContact O-N 2.87Å; T430-M432 PolarHBondContact O-N 3.43Å; T430-M432 PolarHBondContact OG1-N 2.74Å
431G98.3Very high97.7Very high0 Ų031.4 Ų31.40%018%0.176CC..SBendtrans73.55.5-16900000113.7I367 L428 K429I367-G431 PolarHBondContact N-O 3.18Å; L428-G431 PolarHBondContact O-N 2.99Å; K429-G431 VanDerWaalsContact C-N 3.3Å; K429-G431 PolarHBondContact O-N 3.26Å
432M98.8Very high97.7Very high4 Ų430.4 Ų30.42%0.0217%0.17CC..SBendtrans-119.1160.7172.7-61.6174.2-70.200109.2V20 R22 E26 R30 D51 T430 T434V20-M432 HydrophobicContact CG1-CB 4.04Å; V20-M432 HydrophobicContact CG1-CE 4.41Å; V20-M432 HydrophobicContact CG1-SD 4.42Å; R22-M432 HydrophobicContact CB-SD 4.08Å; E26-M432 HydrophobicContact CG-SD 4.02Å; R30-M432 HydrophobicContact CB-CG 3.98Å; R30-M432 HydrophobicContact CB-SD 4.35Å; R30-M432 HydrophobicContact CG-CG 4.11Å; R30-M432 HydrophobicContact CG-SD 4.1Å; D51-M432 HydrophobicContact CB-CE 4.16Å; D51-M432 WeakPolarHBondContact O-CE 3.5Å; T430-M432 PolarHBondContact O-N 3.43Å; T430-M432 PolarHBondContact OG1-N 2.74Å; M432-T434 PolarHBondContact O-N 3.3Å
433L98.8Very high97.7Very high0 Ų028 Ų280%016%0.155CC..EExtended strand (participates in β ladder)trans-72.9109.7175.7-78.2167.7000109.6V20 I21 I367 I379 T381 W391 V426 L428V20-L433 WeakPolarHBondContact CA-O 3.29Å; I21-L433 HydrophobicContact CB-CB 4.11Å; I21-L433 PolarHBondContact N-O 2.78Å; I367-L433 HydrophobicContact CD1-CD1 4.25Å; I367-L433 HydrophobicContact CD1-CG 3.79Å; I379-L433 HydrophobicContact CD1-CD2 4.42Å; I379-L433 HydrophobicContact CG2-CD2 4.35Å; T381-L433 HydrophobicContact CG2-CD1 3.92Å; T381-L433 HydrophobicContact CG2-CD2 3.88Å; T381-L433 HydrophobicContact CG2-CG 4.16Å; W391-L433 HydrophobicContact CB-CD1 4.24Å; W391-L433 HydrophobicContact CD2-CD1 3.54Å; W391-L433 HydrophobicContact CE3-CD1 3.89Å; W391-L433 HydrophobicContact CG-CD1 3.68Å; W391-L433 HydrophobicContact CZ2-CD1 4.45Å; W391-L433 HydrophobicContact CZ3-CD1 4.45Å; V426-L433 HydrophobicContact CG1-CD2 3.71Å; L428-L433 HydrophobicContact CD2-CD2 3.89Å
434T98.8Very high97.6Very high8 Ų829.1 Ų29.15%0.04917%0.165CC..EExtended strand (participates in β ladder)trans-106.8123169.7-52.30000107.9Y19 V20 V426 D427 M432Y19-T434 WeakPolarHBondContact O-CA 3.37Å; V20-T434 HydrophobicContact CG2-CG2 4.25Å; V426-T434 WeakPolarHBondContact CA-O 3.38Å; D427-T434 PolarHBondContact N-O 2.98Å; D427-T434 PolarHBondContact O-N 3.34Å; D427-T434 VanDerWaalsContact O-N 3.13Å; D427-T434 VanDerWaalsContact OD2-CB 3.24Å; D427-T434 WeakPolarHBondContact OD2-CB 3.39Å; D427-T434 VanDerWaalsContact OD2-CG2 3.28Å; D427-T434 WeakPolarHBondContact OD2-CG2 3.31Å; M432-T434 PolarHBondContact O-N 3.3Å
435I98.8Very high97.6Very high0 Ų028.8 Ų28.80%016%0.163CC..EExtended strand (participates in β ladder)trans-106.7133.6-178.4-50.5-60.9000107.9S18 Y19 I21 I379 V393 F424 S425 V426S18-I435 CarbonylContact C-O 3.46Å; S18-I435 WeakPolarHBondContact CA-O 3.5Å; S18-I435 WeakPolarHBondContact CB-O 3.38Å; Y19-I435 HydrophobicContact CD1-CB 3.96Å; Y19-I435 HydrophobicContact CD1-CG2 4.38Å; Y19-I435 HydrophobicContact CE1-CB 3.37Å; Y19-I435 HydrophobicContact CE1-CG1 4.09Å; Y19-I435 HydrophobicContact CE1-CG2 3.46Å; Y19-I435 VanDerWaalsContact CE1-CG2 3.46Å; Y19-I435 HydrophobicContact CE2-CB 4.15Å; Y19-I435 HydrophobicContact CE2-CG1 3.97Å; Y19-I435 PolarHBondContact N-O 3.09Å; Y19-I435 PolarHBondContact O-N 3.33Å; I21-I435 HydrophobicContact CD1-CD1 4.47Å; I21-I435 HydrophobicContact CD1-CG1 4.08Å; I21-I435 HydrophobicContact CG1-CG1 4.39Å; I379-I435 HydrophobicContact CD1-CD1 4.13Å; V393-I435 HydrophobicContact CG1-CD1 4.27Å; V393-I435 HydrophobicContact CG1-CG1 4.24Å; V393-I435 HydrophobicContact CG1-CG2 4.04Å; F424-I435 HydrophobicContact CB-CG2 3.82Å; F424-I435 HydrophobicContact CD2-CD1 4.46Å; F424-I435 HydrophobicContact CD2-CG2 3.83Å; F424-I435 HydrophobicContact CG-CG2 4.03Å; S425-I435 WeakPolarHBondContact O-CA 3.45Å; V426-I435 HydrophobicContact CB-CD1 4.44Å; V426-I435 HydrophobicContact CG1-CD1 4.2Å; V426-I435 HydrophobicContact CG2-CD1 3.79Å
436T98.7Very high97.5Very high14 Ų1426.2 Ų26.29%0.08614%0.144CC..EExtended strand (participates in β ladder)trans-123.7130.1-179.4-60.70000110.9Q16 S18 F424 S425Q16-T436 HydrophobicContact CB-CG2 3.93Å; Q16-T436 HydrophobicContact CG-CG2 4.4Å; S18-T436 WeakPolarHBondContact OG-CB 3.33Å; S18-T436 WeakPolarHBondContact OG-CG2 3.49Å; S18-T436 PolarHBondContact OG-OG1 2.78Å; F424-T436 WeakPolarHBondContact CA-O 3.41Å; S425-T436 PolarHBondContact N-O 3.37Å; S425-T436 PolarHBondContact O-N 3.22Å; S425-T436 PolarHBondContact OG-O 2.84Å
437L98.6Very high97.3Very high0 Ų024.9 Ų24.90%014%0.136CC..EExtended strand (participates in β ladder)trans-104.8129.5176-51.5176.3000109.3Q16 V17 W423 F424 C442 L470 L471 L474 W554Q16-L437 WeakPolarHBondContact CA-O 3.33Å; V17-L437 HydrophobicContact CB-CB 4.42Å; V17-L437 PolarHBondContact N-O 2.77Å; V17-L437 VanDerWaalsContact N-O 3.12Å; V17-L437 PolarHBondContact O-N 3.41Å; W423-L437 HydrophobicContact CE3-CD2 3.96Å; W423-L437 HydrophobicContact CZ3-CD2 3.85Å; F424-L437 HydrophobicContact CB-CD2 3.83Å; L437-C442 HydrophobicContact CB-CB 4.43Å; L437-L470 HydrophobicContact CD1-CD2 3.98Å; L437-L470 HydrophobicContact CD1-CG 4.45Å; L437-L470 HydrophobicContact CD2-CD2 4.15Å; L437-L471 HydrophobicContact CD1-CD2 3.67Å; L437-L471 HydrophobicContact CD1-CG 4.15Å; L437-L474 HydrophobicContact CD1-CD1 4.37Å; L437-W554 HydrophobicContact CB-CH2 4.27Å
438D96.6Very high97.1Very high25 Ų2523.2 Ų23.213%0.13413%0.128CC..  trans-117.8146.2176.8-168-86.2000110.4Q16 S440 D441 C442Q16-D438 WeakPolarHBondContact CG-OD2 3.34Å; Q16-D438 PolarHBondContact NE2-OD2 2.71Å; D438-S440 PolarHBondContact O-N 2.93Å; D438-S440 VanDerWaalsContact O-N 3.1Å; D438-S440 WeakPolarHBondContact OD1-CB 3.34Å; D438-S440 PolarHBondContact OD1-N 3Å; D438-S440 PolarHBondContact OD1-OG 3.19Å; D438-D441 PolarHBondContact O-N 3.18Å; D438-C442 WeakPolarHBondContact O-CB 3.43Å; D438-C442 PolarHBondContact O-N 3.1Å
439E95.4Very high96.8Very high85 Ų8521.2 Ų21.240%0.39712%0.118SC..THydrogen-bonded Turntrans-53.2-32.6178.3-178.3-172-149.600112.8K14 D441 W554K14-E439 IonicContact NZ-OE2 3.14Å; K14-E439 PolarHBondContact NZ-OE2 3.41Å; E439-D441 PolarHBondContact O-N 2.92Å; E439-W554 HydrophobicContact CB-CD2 4.04Å; E439-W554 HydrophobicContact CB-CG 4.02Å; E439-W554 HydrophobicContact CG-CB 3.97Å; E439-W554 HydrophobicContact CG-CD2 4.28Å; E439-W554 HydrophobicContact CG-CG 3.84Å
440S94.2Very high96.4Very high93 Ų9325.5 Ų25.565%0.6514%0.136SC*.THydrogen-bonded Turntrans-69.1-31.4-173.755.20000114.8D438D438-S440 PolarHBondContact O-N 2.93Å; D438-S440 VanDerWaalsContact O-N 3.1Å; D438-S440 WeakPolarHBondContact OD1-CB 3.34Å; D438-S440 PolarHBondContact OD1-N 3Å; D438-S440 PolarHBondContact OD1-OG 3.19Å
441D95.8Very high95.9Very high49 Ų4931.4 Ų31.426%0.26217%0.168SC..THydrogen-bonded Turntrans-133.5-11.4-172.865.9-6.4000114.7W423 D438 E439 F443 A444W423-D441 VanDerWaalsContact CA-O 3.31Å; W423-D441 WeakPolarHBondContact CA-O 3.49Å; W423-D441 WeakPolarHBondContact CB-O 3.41Å; D438-D441 PolarHBondContact O-N 3.18Å; E439-D441 PolarHBondContact O-N 2.92Å; D441-F443 PolarHBondContact O-N 2.93Å; D441-A444 VanDerWaalsContact O-CB 3.25Å; D441-A444 WeakPolarHBondContact O-CB 3.43Å; D441-A444 PolarHBondContact O-N 3.5Å
442C97.4Very high95.6Very high0 Ų031.9 Ų31.90%017%0.172CC..THydrogen-bonded Turntrans-49.9-34.2-178.1-179.80000113.4W423 L437 D438 G467 W554W423-C442 WeakPolarHBondContact O-CA 3.18Å; L437-C442 HydrophobicContact CB-CB 4.43Å; D438-C442 WeakPolarHBondContact O-CB 3.43Å; D438-C442 PolarHBondContact O-N 3.1Å; C442-G467 WeakPolarHBondContact O-CA 3.24Å; C442-W554 HydrophobicContact CB-CH2 4.27Å; C442-W554 HydrophobicContact CB-CZ3 3.89Å
443F97.1Very high95.2Very high36 Ų3634.9 Ų34.916%0.15820%0.204CC..THydrogen-bonded Turntrans-101.19.8-177.1-52.9-49.7000114.5D441 A445 N465 L471 W554 I558 P565D441-F443 PolarHBondContact O-N 2.93Å; F443-A445 VanDerWaalsContact C-N 3.32Å; F443-A445 PolarHBondContact O-N 3.15Å; F443-N465 WeakPolarHBondContact CD1-OD1 3.13Å; F443-N465 PolarHBondContact O-ND2 2.83Å; F443-L471 HydrophobicContact CE1-CD1 3.73Å; F443-L471 HydrophobicContact CZ-CD1 3.82Å; F443-W554 HydrophobicContact CE1-CZ3 4.38Å; F443-W554 AromaticContact CE2-CE3 3.57Å; F443-W554 HydrophobicContact CE2-CE3 3.57Å; F443-W554 HydrophobicContact CE2-CZ3 4.03Å; F443-W554 AromaticContact CZ-CE3 3.46Å; F443-W554 HydrophobicContact CZ-CE3 3.46Å; F443-W554 VanDerWaalsContact CZ-CE3 3.46Å; F443-W554 AromaticContact CZ-CZ3 3.62Å; F443-W554 HydrophobicContact CZ-CZ3 3.62Å; F443-I558 HydrophobicContact CD1-CG1 4.49Å; F443-I558 HydrophobicContact CE1-CD1 4.41Å; F443-I558 HydrophobicContact CE1-CG1 3.63Å; F443-I558 HydrophobicContact CE2-CG1 4.07Å; F443-I558 HydrophobicContact CZ-CB 4.48Å; F443-I558 HydrophobicContact CZ-CD1 4.2Å; F443-I558 HydrophobicContact CZ-CG1 3.36Å; F443-P565 HydrophobicContact CB-CB 3.92Å; F443-P565 HydrophobicContact CB-CG 3.79Å; F443-P565 HydrophobicContact CD1-CG 4.21Å; F443-P565 HydrophobicContact CG-CB 4.27Å; F443-P565 HydrophobicContact CG-CG 4.02Å
444A96.1Very high94.9Very high25 Ų2536 Ų3621%0.20721%0.208CC..  trans-71.3-25.9-177.200000113.5P421 D441 W446 N568P421-A444 HydrophobicContact CB-CB 3.91Å; D441-A444 VanDerWaalsContact O-CB 3.25Å; D441-A444 WeakPolarHBondContact O-CB 3.43Å; D441-A444 PolarHBondContact O-N 3.5Å; A444-W446 PolarHBondContact O-N 3.28Å; A444-N568 PolarHBondContact O-ND2 3.5Å; A444-N568 VanDerWaalsContact O-ND2 3.08Å
445A96.9Very high94.2Very high0 Ų041.1 Ų41.10%025%0.245CC..  trans-94.796.7-172.300000112.9V420 W423 F443 L466V420-A445 HydrophobicContact CG1-CB 3.71Å; W423-A445 HydrophobicContact CB-CB 3.85Å; W423-A445 HydrophobicContact CG-CB 3.63Å; F443-A445 VanDerWaalsContact C-N 3.32Å; F443-A445 PolarHBondContact O-N 3.15Å; A445-L466 HydrophobicContact CB-CB 4.3Å; A445-L466 HydrophobicContact CB-CD1 4.13Å; A445-L466 HydrophobicContact CB-CG 4.33Å; A445-L466 PolarHBondContact O-N 3.33Å
446W96.1Very high93Very high6 Ų643.3 Ų43.32%0.02326%0.26CS..EExtended strand (participates in β ladder)trans-95.1136.3164.3-7089.6000111A444 K463 L464 N465 M564 P565 K566 F567 M595 R660A444-W446 PolarHBondContact O-N 3.28Å; W446-K463 HydrophobicContact CE3-CB 4.1Å; W446-K463 HydrophobicContact CZ3-CB 4.45Å; W446-K463 WeakPolarHBondContact CZ3-O 3.29Å; W446-L464 CarbonylContact C-O 3.54Å; W446-L464 WeakPolarHBondContact CA-O 3.47Å; W446-N465 HydrophobicContact CD2-CB 4.06Å; W446-N465 VanDerWaalsContact CE2-ND2 3.35Å; W446-N465 HydrophobicContact CE3-CB 4.01Å; W446-N465 HydrophobicContact CH2-CB 3.96Å; W446-N465 HydrophobicContact CZ2-CB 3.94Å; W446-N465 HydrophobicContact CZ3-CB 3.98Å; W446-N465 PolarHBondContact NE1-ND2 2.71Å; W446-M564 HydrophobicContact CH2-CB 4.46Å; W446-M564 HydrophobicContact CH2-CE 3.79Å; W446-M564 HydrophobicContact CZ3-CE 4.1Å; W446-P565 HydrophobicContact CZ2-CB 4.31Å; W446-P565 HydrophobicContact CZ2-CG 3.69Å; W446-P565 WeakPolarHBondContact CZ2-O 3.28Å; W446-K566 PolarHBondContact NE1-O 3.16Å; W446-F567 AromaticContact CD2-CD1 3.76Å; W446-F567 HydrophobicContact CD2-CD1 3.76Å; W446-F567 AromaticContact CD2-CE1 3.7Å; W446-F567 HydrophobicContact CD2-CE1 3.7Å; W446-F567 AromaticContact CE2-CD1 3.97Å; W446-F567 HydrophobicContact CE3-CD1 4Å; W446-F567 AromaticContact CE3-CE1 3.43Å; W446-F567 HydrophobicContact CE3-CE1 3.43Å; W446-F567 VanDerWaalsContact CE3-CE1 3.43Å; W446-F567 HydrophobicContact CE3-CZ 4.33Å; W446-F567 HydrophobicContact CG-CD1 4.1Å; W446-F567 HydrophobicContact CG-CE1 4.39Å; W446-F567 HydrophobicContact CH2-CE1 4.01Å; W446-F567 HydrophobicContact CH2-CZ 4.32Å; W446-F567 HydrophobicContact CZ2-CD1 4.38Å; W446-F567 HydrophobicContact CZ2-CE1 4.29Å; W446-F567 HydrophobicContact CZ3-CD1 4.37Å; W446-F567 AromaticContact CZ3-CE1 3.58Å; W446-F567 HydrophobicContact CZ3-CE1 3.58Å; W446-F567 HydrophobicContact CZ3-CZ 4.05Å; W446-M595 HydrophobicContact CB-CE 3.52Å; W446-M595 HydrophobicContact CB-CG 4.4Å; W446-M595 HydrophobicContact CB-SD 3.43Å; W446-M595 WeakPolarHBondContact CB-SD 3.45Å; W446-M595 HydrophobicContact CG-CE 4.26Å; W446-M595 VanDerWaalsContact O-SD 3.38Å; W446-R660 VanDerWaalsContact O-CZ 3.3Å; W446-R660 PolarHBondContact O-NH1 3.08Å; W446-R660 PolarHBondContact O-NH2 3.26Å
447V94.9Very high91.6Very high12 Ų1248.3 Ų48.37%0.07330%0.296CS..EExtended strand (participates in β ladder)trans-140.5159.3177-64.80000109.9V420 A452 K463 L464 L466V420-V447 HydrophobicContact CG1-CG1 4.19Å; V420-V447 HydrophobicContact CG2-CG1 4.09Å; V447-A452 HydrophobicContact CG2-CB 3.97Å; V447-K463 CarbonylContact O-C 3.51Å; V447-K463 WeakPolarHBondContact O-CA 3.44Å; V447-L464 HydrophobicContact CG2-CB 4.47Å; V447-L464 PolarHBondContact N-O 3.3Å; V447-L464 PolarHBondContact O-N 3.4Å; V447-L466 HydrophobicContact CG1-CD1 4.31Å; V447-L466 HydrophobicContact CG2-CD1 4.4Å; V447-L466 HydrophobicContact CG2-CD2 3.54Å; V447-L466 HydrophobicContact CG2-CG 3.91Å
448S93Very high90.4Very high5 Ų554.9 Ų54.94%0.03533%0.331CS..EExtended strand (participates in β ladder)trans-72.1153.2169.475.40000111.1K450 D451 A452 D461S448-K450 VanDerWaalsContact C-N 3.27Å; S448-K450 PolarHBondContact O-N 3.36Å; S448-D451 PolarHBondContact O-N 3.39Å; S448-D451 WeakPolarHBondContact OG-CB 3.42Å; S448-D451 PolarHBondContact OG-N 3.48Å; S448-D451 PolarHBondContact OG-OD2 3.27Å; S448-A452 WeakPolarHBondContact O-CB 3.21Å; S448-A452 PolarHBondContact O-N 2.73Å; S448-D461 WeakPolarHBondContact CB-OD1 3.17Å; S448-D461 WeakPolarHBondContact CB-OD2 3.37Å
449A91.9Very high89.3Confident3 Ų357.1 Ų57.13%0.02536%0.36CS..THydrogen-bonded Turntrans-60.2-42174.600000111A452 G453 F454 D461 P462 L464A449-A452 CarbonylContact O-C 3.53Å; A449-A452 PolarHBondContact O-N 2.89Å; A449-G453 PolarHBondContact O-N 2.79Å; A449-G453 VanDerWaalsContact O-N 3.13Å; A449-F454 CarbonylContact C-O 3.39Å; A449-F454 HydrophobicContact CB-CB 4.41Å; A449-F454 PolarHBondContact O-N 2.76Å; A449-F454 VanDerWaalsContact O-O 3.11Å; A449-D461 PolarHBondContact N-OD1 2.59Å; A449-D461 VanDerWaalsContact N-OD1 3.11Å; A449-P462 HydrophobicContact CB-CG 3.97Å; A449-P462 PolarHBondContact N-O 2.92Å; A449-L464 HydrophobicContact CB-CD1 3.78Å; A449-L464 HydrophobicContact CB-CG 4.15Å
450K89.6Confident88.8Confident166 Ų16656.2 Ų56.272%0.72236%0.363SS*.THydrogen-bonded Turntrans-63.3-44.8179.1-169.7177.2-179.9179.30112.8S448 A452 G453 D461S448-K450 VanDerWaalsContact C-N 3.27Å; S448-K450 PolarHBondContact O-N 3.36Å; K450-A452 VanDerWaalsContact C-N 3.26Å; K450-A452 PolarHBondContact O-N 2.97Å; K450-G453 WeakPolarHBondContact O-CA 3.31Å; K450-G453 PolarHBondContact O-N 2.78Å; K450-D461 WeakPolarHBondContact CB-OD1 3.42Å; K450-D461 PolarHBondContact N-OD1 3.42Å
451D89.2Confident88.4Confident129 Ų12954.9 Ų54.969%0.6935%0.348SS*.THydrogen-bonded Turntrans-68.3-29.6177.2-62.7-35.1000111.8S448 G453S448-D451 PolarHBondContact O-N 3.39Å; S448-D451 WeakPolarHBondContact OG-CB 3.42Å; S448-D451 PolarHBondContact OG-N 3.48Å; S448-D451 PolarHBondContact OG-OD2 3.27Å; D451-G453 PolarHBondContact O-N 3.24Å
452A91.1Very high88.2Confident9 Ų954.7 Ų54.77%0.07435%0.35CS..THydrogen-bonded Turntrans-76.72.2169.200000113R377 V447 S448 A449 K450 F454R377-A452 PolarHBondContact NH1-O 2.83Å; V447-A452 HydrophobicContact CG2-CB 3.97Å; S448-A452 WeakPolarHBondContact O-CB 3.21Å; S448-A452 PolarHBondContact O-N 2.73Å; A449-A452 CarbonylContact O-C 3.53Å; A449-A452 PolarHBondContact O-N 2.89Å; K450-A452 VanDerWaalsContact C-N 3.26Å; K450-A452 PolarHBondContact O-N 2.97Å; A452-F454 VanDerWaalsContact C-N 3.29Å; A452-F454 HydrophobicContact CB-CD2 3.65Å; A452-F454 HydrophobicContact CB-CE2 3.89Å; A452-F454 PolarHBondContact O-N 3.09Å
453G91.1Very high88Confident67 Ų6758.8 Ų58.869%0.69137%0.368SS*.THydrogen-bonded Turntrans66.529.117900000113.8A449 K450 D451A449-G453 PolarHBondContact O-N 2.79Å; A449-G453 VanDerWaalsContact O-N 3.13Å; K450-G453 WeakPolarHBondContact O-CA 3.31Å; K450-G453 PolarHBondContact O-N 2.78Å; D451-G453 PolarHBondContact O-N 3.24Å
454F91.5Very high87.9Confident23 Ų2357.4 Ų57.410%0.10136%0.362CS..  trans-106.5135.4169.4-59.4-61.4000109.6L394 A449 A452 L464 Y511 F512L394-F454 HydrophobicContact CD2-CE2 4.08Å; L394-F454 HydrophobicContact CD2-CZ 4.1Å; A449-F454 CarbonylContact C-O 3.39Å; A449-F454 HydrophobicContact CB-CB 4.41Å; A449-F454 PolarHBondContact O-N 2.76Å; A449-F454 VanDerWaalsContact O-O 3.11Å; A452-F454 VanDerWaalsContact C-N 3.29Å; A452-F454 HydrophobicContact CB-CD2 3.65Å; A452-F454 HydrophobicContact CB-CE2 3.89Å; A452-F454 PolarHBondContact O-N 3.09Å; F454-L464 HydrophobicContact CD2-CD1 3.75Å; F454-L464 HydrophobicContact CE2-CD1 4.37Å; F454-Y511 HydrophobicContact CB-CD1 3.88Å; F454-Y511 HydrophobicContact CB-CE1 4.38Å; F454-Y511 HydrophobicContact CD1-CD1 4.28Å; F454-Y511 HydrophobicContact CD2-CD1 4.14Å; F454-Y511 AromaticContact CG-CD1 3.86Å; F454-Y511 HydrophobicContact CG-CD1 3.86Å; F454-Y511 HydrophobicContact CG-CG 4.48Å; F454-F512 HydrophobicContact CE1-CB 4.43Å; F454-F512 HydrophobicContact CE1-CD1 4.31Å; F454-F512 HydrophobicContact CE2-CD1 4.47Å; F454-F512 AromaticContact CZ-CD1 3.68Å; F454-F512 HydrophobicContact CZ-CD1 3.68Å; F454-F512 HydrophobicContact CZ-CE1 4.39Å; F454-F512 HydrophobicContact CZ-CG 4.48Å
455S83.4Confident88Confident117 Ų11756.2 Ų56.282%0.81835%0.352SS*.  trans-105.7135.7176.954.50000110.6
456S74.4Confident88Confident45 Ų4556.3 Ų56.332%0.31535%0.353SS..  trans-91.9148.8167.161.90000110.1D458 G459 S460S456-D458 PolarHBondContact O-N 3.47Å; S456-G459 PolarHBondContact OG-N 3.48Å; S456-S460 WeakPolarHBondContact CB-O 3.41Å; S456-S460 PolarHBondContact OG-N 2.98Å; S456-S460 PolarHBondContact OG-O 3.06Å
457S68.8Low88.1Confident119 Ų11956 Ų5683%0.83235%0.352SS*.THydrogen-bonded Turntrans-65.7-29.2173.648.20000112.5
458D73.5Confident88.2Confident138 Ų13855.5 Ų55.574%0.73835%0.348SS*.THydrogen-bonded Turntrans-97.77.8-167.7-53.5-7.2000112.2S456 S460S456-D458 PolarHBondContact O-N 3.47Å; D458-S460 PolarHBondContact O-N 3.18Å; D458-S460 VanDerWaalsContact O-N 3.14Å
459G74.1Confident88.4Confident72 Ų7255.7 Ų55.774%0.74235%0.349SS*.SBendtrans70.51.5-176.800000114.8S456S456-G459 PolarHBondContact OG-N 3.48Å
460S84.4Confident88.7Confident67 Ų6755.5 Ų55.547%0.46935%0.348SS..  trans-71.5143.8177.464.50000112.1S456 D458 P462S456-S460 WeakPolarHBondContact CB-O 3.41Å; S456-S460 PolarHBondContact OG-N 2.98Å; S456-S460 PolarHBondContact OG-O 3.06Å; D458-S460 PolarHBondContact O-N 3.18Å; D458-S460 VanDerWaalsContact O-N 3.14Å; S460-P462 VanDerWaalsContact C-CD 3.43Å; S460-P462 WeakPolarHBondContact O-CD 3.39Å
461D86.9Confident89.2Confident64 Ų6447.7 Ų47.734%0.34231%0.314SS..  trans-115.174.5178.1179.944.3000110.9S448 A449 K450 K463S448-D461 WeakPolarHBondContact CB-OD1 3.17Å; S448-D461 WeakPolarHBondContact CB-OD2 3.37Å; A449-D461 PolarHBondContact N-OD1 2.59Å; A449-D461 VanDerWaalsContact N-OD1 3.11Å; K450-D461 WeakPolarHBondContact CB-OD1 3.42Å; K450-D461 PolarHBondContact N-OD1 3.42Å; D461-K463 IonicContact OD2-NZ 3.3Å; D461-K463 PolarHBondContact OD2-NZ 3.06Å
462P91.4Very high89.5Confident46 Ų4642.6 Ų42.630%0.29929%0.286SS..  trans-65150.4-177.527.4-34000111A449 S460 L464A449-P462 HydrophobicContact CB-CG 3.97Å; A449-P462 PolarHBondContact N-O 2.92Å; S460-P462 VanDerWaalsContact C-CD 3.43Å; S460-P462 WeakPolarHBondContact O-CD 3.39Å; P462-L464 HydrophobicContact CB-CD2 4.49Å; P462-L464 HydrophobicContact CG-CD2 4.35Å
463K92.7Very high89.9Confident85 Ų8542.2 Ų42.237%0.3728%0.282SS..EExtended strand (participates in β ladder)trans-84.6127.5173.5-55.2-50.6178.6-1620109.2W446 V447 D461 F567 M595W446-K463 HydrophobicContact CE3-CB 4.1Å; W446-K463 HydrophobicContact CZ3-CB 4.45Å; W446-K463 WeakPolarHBondContact CZ3-O 3.29Å; V447-K463 CarbonylContact O-C 3.51Å; V447-K463 WeakPolarHBondContact O-CA 3.44Å; D461-K463 IonicContact OD2-NZ 3.3Å; D461-K463 PolarHBondContact OD2-NZ 3.06Å; K463-F567 HydrophobicContact CB-CE1 3.73Å; K463-F567 HydrophobicContact CB-CZ 4.12Å; K463-F567 HydrophobicContact CG-CE1 4.29Å; K463-M595 HydrophobicContact CB-CE 3.97Å; K463-M595 HydrophobicContact CD-CE 4.1Å; K463-M595 HydrophobicContact CD-SD 4.08Å; K463-M595 HydrophobicContact CG-CE 3.83Å; K463-M595 HydrophobicContact CG-SD 4.42Å
464L94.9Very high90.2Very high7 Ų739 Ų394%0.03725%0.25CC..EExtended strand (participates in β ladder)trans-112137.9-174-56.9-176000110.2W446 V447 A449 F454 P462 L469 Y511W446-L464 CarbonylContact C-O 3.54Å; W446-L464 WeakPolarHBondContact CA-O 3.47Å; V447-L464 HydrophobicContact CG2-CB 4.47Å; V447-L464 PolarHBondContact N-O 3.3Å; V447-L464 PolarHBondContact O-N 3.4Å; A449-L464 HydrophobicContact CB-CD1 3.78Å; A449-L464 HydrophobicContact CB-CG 4.15Å; F454-L464 HydrophobicContact CD2-CD1 3.75Å; F454-L464 HydrophobicContact CE2-CD1 4.37Å; P462-L464 HydrophobicContact CB-CD2 4.49Å; P462-L464 HydrophobicContact CG-CD2 4.35Å; L464-L469 HydrophobicContact CB-CD1 3.88Å; L464-L469 HydrophobicContact CD1-CD1 4.01Å; L464-L469 HydrophobicContact CG-CD1 4.35Å; L464-Y511 HydrophobicContact CD1-CD1 4.28Å; L464-Y511 HydrophobicContact CD1-CE1 4.04Å; L464-Y511 HydrophobicContact CD2-CE1 4.18Å; L464-Y511 HydrophobicContact CD2-CE2 3.83Å; L464-Y511 WeakPolarHBondContact CD2-OH 3.36Å
465N97.1Very high90.5Very high0 Ų038.1 Ų38.10%025%0.246CC..EExtended strand (participates in β ladder)trans-96.7114.7171.4-170.2-85.3000109.9F443 W446 G467 G468 L469 M564 P565F443-N465 WeakPolarHBondContact CD1-OD1 3.13Å; F443-N465 PolarHBondContact O-ND2 2.83Å; W446-N465 HydrophobicContact CD2-CB 4.06Å; W446-N465 VanDerWaalsContact CE2-ND2 3.35Å; W446-N465 HydrophobicContact CE3-CB 4.01Å; W446-N465 HydrophobicContact CH2-CB 3.96Å; W446-N465 HydrophobicContact CZ2-CB 3.94Å; W446-N465 HydrophobicContact CZ3-CB 3.98Å; W446-N465 PolarHBondContact NE1-ND2 2.71Å; N465-G467 PolarHBondContact O-N 3.02Å; N465-G468 PolarHBondContact O-N 3.11Å; N465-G468 PolarHBondContact OD1-N 3.11Å; N465-L469 WeakPolarHBondContact O-CG 3.43Å; N465-L469 PolarHBondContact O-N 3Å; N465-M564 HydrophobicContact CB-CE 3.99Å; N465-P565 HydrophobicContact CB-CG 4.31Å
466L97.9Very high91.2Very high3 Ų333 Ų332%0.01621%0.209CC..Hα-helixtrans-61.6-46.8-172-65-175.2000112.9L394 W423 A445 V447 L469 L470L394-L466 HydrophobicContact CD1-CB 4.41Å; L394-L466 HydrophobicContact CD1-CD2 4.37Å; L394-L466 WeakPolarHBondContact CD1-O 3.16Å; L394-L466 HydrophobicContact CD2-CD2 3.91Å; W423-L466 HydrophobicContact CD2-CB 4.08Å; W423-L466 HydrophobicContact CE3-CB 4.44Å; W423-L466 HydrophobicContact CH2-CB 4.22Å; W423-L466 HydrophobicContact CZ2-CB 3.83Å; W423-L466 HydrophobicContact CZ2-CD1 4.18Å; W423-L466 HydrophobicContact CZ3-CB 4.5Å; A445-L466 HydrophobicContact CB-CB 4.3Å; A445-L466 HydrophobicContact CB-CD1 4.13Å; A445-L466 HydrophobicContact CB-CG 4.33Å; A445-L466 PolarHBondContact O-N 3.33Å; V447-L466 HydrophobicContact CG1-CD1 4.31Å; V447-L466 HydrophobicContact CG2-CD1 4.4Å; V447-L466 HydrophobicContact CG2-CD2 3.54Å; V447-L466 HydrophobicContact CG2-CG 3.91Å; L466-L469 PolarHBondContact O-N 2.94Å; L466-L470 WeakPolarHBondContact O-CB 3.41Å; L466-L470 PolarHBondContact O-N 3.22Å
467G97.9Very high92.2Very high0 Ų034 Ų340%021%0.207CC..Hα-helixtrans-65.6-39178.300000112.7C442 N465 L470 L471C442-G467 WeakPolarHBondContact O-CA 3.24Å; N465-G467 PolarHBondContact O-N 3.02Å; G467-L470 PolarHBondContact O-N 3Å; G467-L471 WeakPolarHBondContact O-CG 3.28Å; G467-L471 PolarHBondContact O-N 3.48Å
468G97.3Very high93.5Very high0 Ų028.3 Ų28.30%017%0.168CC..Hα-helixtrans-62.2-46.9175.700000113.1N465 L470 L471 Q472N465-G468 PolarHBondContact O-N 3.11Å; N465-G468 PolarHBondContact OD1-N 3.11Å; G468-L470 VanDerWaalsContact C-N 3.31Å; G468-L470 PolarHBondContact O-N 3.24Å; G468-L471 PolarHBondContact O-N 2.8Å; G468-Q472 WeakPolarHBondContact O-CG 3.4Å; G468-Q472 PolarHBondContact O-N 2.76Å
469L97.6Very high94.5Very high9 Ų924.4 Ų24.45%0.04715%0.15CC..Hα-helixtrans-61.3-41.3175.8-66.8179.8000111.7L464 N465 L466 Q472 A473 N509 Y511 F512L464-L469 HydrophobicContact CB-CD1 3.88Å; L464-L469 HydrophobicContact CD1-CD1 4.01Å; L464-L469 HydrophobicContact CG-CD1 4.35Å; N465-L469 WeakPolarHBondContact O-CG 3.43Å; N465-L469 PolarHBondContact O-N 3Å; L466-L469 PolarHBondContact O-N 2.94Å; L469-Q472 PolarHBondContact O-N 2.65Å; L469-A473 PolarHBondContact O-N 3.22Å; L469-N509 HydrophobicContact CB-CB 4.41Å; L469-N509 HydrophobicContact CD2-CB 3.72Å; L469-N509 PolarHBondContact O-ND2 2.82Å; L469-Y511 HydrophobicContact CD1-CD2 4.28Å; L469-Y511 HydrophobicContact CD2-CD2 3.74Å; L469-Y511 HydrophobicContact CD2-CE2 4.05Å; L469-F512 HydrophobicContact CB-CE1 3.77Å; L469-F512 HydrophobicContact CB-CZ 4.06Å; L469-F512 HydrophobicContact CD1-CE1 4.3Å
470L98.6Very high95.5Very high0 Ų026.5 Ų26.50%014%0.136CC..Hα-helixtrans-64-46.4179.1-178.860.9000112.1Y19 L394 W423 L437 L466 G467 G468 Q472 A473 L474 F512 V514Y19-L470 HydrophobicContact CE1-CD1 4.5Å; Y19-L470 HydrophobicContact CE1-CD2 3.57Å; Y19-L470 HydrophobicContact CE1-CG 4.43Å; Y19-L470 WeakPolarHBondContact OH-CD2 3.34Å; L394-L470 HydrophobicContact CD1-CB 4.13Å; L394-L470 WeakPolarHBondContact O-CD1 3.3Å; W423-L470 HydrophobicContact CH2-CB 4.46Å; W423-L470 HydrophobicContact CH2-CD2 3.77Å; W423-L470 HydrophobicContact CZ3-CB 4.24Å; W423-L470 HydrophobicContact CZ3-CD2 3.58Å; L437-L470 HydrophobicContact CD1-CD2 3.98Å; L437-L470 HydrophobicContact CD1-CG 4.45Å; L437-L470 HydrophobicContact CD2-CD2 4.15Å; L466-L470 WeakPolarHBondContact O-CB 3.41Å; L466-L470 PolarHBondContact O-N 3.22Å; G467-L470 PolarHBondContact O-N 3Å; G468-L470 VanDerWaalsContact C-N 3.31Å; G468-L470 PolarHBondContact O-N 3.24Å; L470-Q472 VanDerWaalsContact C-N 3.27Å; L470-Q472 PolarHBondContact O-N 3.01Å; L470-A473 PolarHBondContact O-N 3.22Å; L470-A473 VanDerWaalsContact O-N 3.09Å; L470-L474 HydrophobicContact CD1-CD1 4.38Å; L470-L474 HydrophobicContact CD1-CD2 4.49Å; L470-L474 HydrophobicContact CD1-CG 4.16Å; L470-L474 HydrophobicContact CG-CD1 4.02Å; L470-L474 HydrophobicContact CG-CG 4.25Å; L470-L474 WeakPolarHBondContact O-CG 3.4Å; L470-L474 PolarHBondContact O-N 2.94Å; L470-F512 HydrophobicContact CD1-CE2 4.49Å; L470-V514 HydrophobicContact CD1-CG1 4.06Å
471L98.5Very high95.8Very high2 Ų223.6 Ų23.61%0.0112%0.115CC..Hα-helixtrans-59.1-40.4178.1-71.7172.6000112V17 L437 F443 G467 G468 A473 L474 L475 W554 V555 T559V17-L471 HydrophobicContact CB-CD2 4.28Å; V17-L471 HydrophobicContact CG1-CD2 4.25Å; V17-L471 HydrophobicContact CG2-CD2 4.16Å; L437-L471 HydrophobicContact CD1-CD2 3.67Å; L437-L471 HydrophobicContact CD1-CG 4.15Å; F443-L471 HydrophobicContact CE1-CD1 3.73Å; F443-L471 HydrophobicContact CZ-CD1 3.82Å; G467-L471 WeakPolarHBondContact O-CG 3.28Å; G467-L471 PolarHBondContact O-N 3.48Å; G468-L471 PolarHBondContact O-N 2.8Å; L471-A473 VanDerWaalsContact C-N 3.34Å; L471-L474 PolarHBondContact O-N 3.29Å; L471-L475 PolarHBondContact O-N 2.77Å; L471-L475 VanDerWaalsContact O-N 3.08Å; L471-W554 HydrophobicContact CD1-CE3 4.38Å; L471-W554 HydrophobicContact CD1-CH2 4.35Å; L471-W554 HydrophobicContact CD1-CZ3 3.69Å; L471-W554 HydrophobicContact CD2-CH2 4.49Å; L471-V555 HydrophobicContact CD1-CG1 4.37Å; L471-V555 HydrophobicContact CD1-CG2 4.24Å; L471-V555 HydrophobicContact CD2-CG1 4.2Å; L471-V555 HydrophobicContact CD2-CG2 4.18Å; L471-T559 HydrophobicContact CB-CG2 3.69Å
472Q97.4Very high95.8Very high22 Ų2225 Ų2510%0.10312%0.116CC..Hα-helixtrans-64.8-36.4175.8-72.3176.1-2.300112.4G468 L469 L470 L475 E476 N509 I558 T559G468-Q472 WeakPolarHBondContact O-CG 3.4Å; G468-Q472 PolarHBondContact O-N 2.76Å; L469-Q472 PolarHBondContact O-N 2.65Å; L470-Q472 VanDerWaalsContact C-N 3.27Å; L470-Q472 PolarHBondContact O-N 3.01Å; Q472-L475 CarbonylContact O-C 3.39Å; Q472-E476 WeakPolarHBondContact O-CA 3.42Å; Q472-E476 PolarHBondContact O-N 2.85Å; Q472-E476 VanDerWaalsContact O-N 3.08Å; Q472-N509 HydrophobicContact CB-CB 3.89Å; Q472-N509 VanDerWaalsContact OE1-CB 3.24Å; Q472-I558 PolarHBondContact NE2-O 3.37Å; Q472-I558 VanDerWaalsContact NE2-O 3.11Å; Q472-T559 HydrophobicContact CG-CG2 4.18Å
473A98.1Very high94.8Very high0 Ų025.1 Ų25.10%011%0.113CC..Hα-helixtrans-70.7-41.9174.200000112.2L469 L470 L471 L475 E476 F512 V514L469-A473 PolarHBondContact O-N 3.22Å; L470-A473 PolarHBondContact O-N 3.22Å; L470-A473 VanDerWaalsContact O-N 3.09Å; L471-A473 VanDerWaalsContact C-N 3.34Å; A473-L475 VanDerWaalsContact C-N 3.26Å; A473-L475 PolarHBondContact O-N 3.06Å; A473-E476 VanDerWaalsContact O-CB 3.3Å; A473-E476 WeakPolarHBondContact O-CB 3.3Å; A473-E476 PolarHBondContact O-N 2.96Å; A473-F512 HydrophobicContact CB-CD2 4.2Å; A473-F512 HydrophobicContact CB-CE2 3.61Å; A473-F512 HydrophobicContact CB-CZ 4.25Å; A473-V514 HydrophobicContact CB-CG1 3.92Å; A473-V514 HydrophobicContact CB-CG2 4.44Å
474L98.5Very high93.2Very high1 Ų125.7 Ų25.71%0.00512%0.121CC..Hα-helixtrans-62.3-33.7178.2-67.9172.8000112.2V17 Y19 L437 L470 L471 V514 T518 V520 C535V17-L474 HydrophobicContact CG1-CD1 4.27Å; Y19-L474 HydrophobicContact CD1-CD1 3.95Å; Y19-L474 HydrophobicContact CD1-CD2 4.22Å; Y19-L474 HydrophobicContact CD2-CD2 4.33Å; Y19-L474 HydrophobicContact CE1-CD1 4.5Å; Y19-L474 HydrophobicContact CG-CD1 4.42Å; Y19-L474 HydrophobicContact CG-CD2 3.9Å; L437-L474 HydrophobicContact CD1-CD1 4.37Å; L470-L474 HydrophobicContact CD1-CD1 4.38Å; L470-L474 HydrophobicContact CD1-CD2 4.49Å; L470-L474 HydrophobicContact CD1-CG 4.16Å; L470-L474 HydrophobicContact CG-CD1 4.02Å; L470-L474 HydrophobicContact CG-CG 4.25Å; L470-L474 WeakPolarHBondContact O-CG 3.4Å; L470-L474 PolarHBondContact O-N 2.94Å; L471-L474 PolarHBondContact O-N 3.29Å; L474-V514 HydrophobicContact CD2-CG1 4.31Å; L474-V514 HydrophobicContact CD2-CG2 4.31Å; L474-T518 HydrophobicContact CD2-CG2 4.36Å; L474-V520 HydrophobicContact CB-CG2 4.27Å; L474-V520 HydrophobicContact CD2-CG2 4.08Å; L474-C535 PolarHBondContact O-SG 3.15Å
475L97.9Very high90.9Very high3 Ų327.8 Ų27.82%0.01614%0.135CC..THydrogen-bonded Turntrans-107.523.7179.7-65.6177.2000113.4L471 Q472 A473 F477 W478 T481 F522 L547 V551 V555 T559L471-L475 PolarHBondContact O-N 2.77Å; L471-L475 VanDerWaalsContact O-N 3.08Å; Q472-L475 CarbonylContact O-C 3.39Å; A473-L475 VanDerWaalsContact C-N 3.26Å; A473-L475 PolarHBondContact O-N 3.06Å; L475-F477 VanDerWaalsContact C-N 3.26Å; L475-F477 PolarHBondContact O-N 3.25Å; L475-W478 HydrophobicContact CB-CB 4.41Å; L475-W478 HydrophobicContact CB-CE3 4.43Å; L475-W478 HydrophobicContact CD1-CE3 4.02Å; L475-W478 HydrophobicContact CD1-CZ3 4.25Å; L475-W478 WeakPolarHBondContact O-CB 3.42Å; L475-W478 PolarHBondContact O-N 3.26Å; L475-W478 VanDerWaalsContact O-N 3.13Å; L475-T481 HydrophobicContact CB-CG2 4.22Å; L475-T481 PolarHBondContact O-OG1 2.84Å; L475-T481 VanDerWaalsContact O-OG1 3.06Å; L475-F522 HydrophobicContact CD1-CZ 4.49Å; L475-F522 HydrophobicContact CD2-CZ 4.16Å; L475-L547 HydrophobicContact CD2-CD1 4.41Å; L475-L547 HydrophobicContact CD2-CD2 4.02Å; L475-V551 HydrophobicContact CD1-CG1 4.41Å; L475-V551 HydrophobicContact CD1-CG2 4.47Å; L475-V555 HydrophobicContact CD1-CG1 3.82Å; L475-T559 HydrophobicContact CD1-CG2 4.35Å
476E96.5Very high88.6Confident11 Ų1134.9 Ų34.95%0.05117%0.17CC..THydrogen-bonded Turntrans-59.6-36-177.2174.9174.9179.200112.8Q472 A473 K507 Q513Q472-E476 WeakPolarHBondContact O-CA 3.42Å; Q472-E476 PolarHBondContact O-N 2.85Å; Q472-E476 VanDerWaalsContact O-N 3.08Å; A473-E476 VanDerWaalsContact O-CB 3.3Å; A473-E476 WeakPolarHBondContact O-CB 3.3Å; A473-E476 PolarHBondContact O-N 2.96Å; E476-K507 HydrophobicContact CG-CB 4.4Å; E476-Q513 PolarHBondContact OE1-NE2 2.95Å; E476-Q513 WeakPolarHBondContact OE2-CG 3.34Å
477F96.3Very high86.3Confident64 Ų6441 Ų4128%0.28120%0.203SC..THydrogen-bonded Turntrans-84.4-9.8-177.9-63.8-86.9000113.4L475 P479 C535L475-F477 VanDerWaalsContact C-N 3.26Å; L475-F477 PolarHBondContact O-N 3.25Å; F477-P479 WeakPolarHBondContact O-CD 2.94Å; F477-C535 WeakPolarHBondContact CD2-O 3.44Å
478W96.8Very high83.8Confident0 Ų047.3 Ų47.30%023%0.232CC..  trans-72118-179.8-173.930.4000110.3L475 R480 T481 S544 L547 N548 V551 V560L475-W478 HydrophobicContact CB-CB 4.41Å; L475-W478 HydrophobicContact CB-CE3 4.43Å; L475-W478 HydrophobicContact CD1-CE3 4.02Å; L475-W478 HydrophobicContact CD1-CZ3 4.25Å; L475-W478 WeakPolarHBondContact O-CB 3.42Å; L475-W478 PolarHBondContact O-N 3.26Å; L475-W478 VanDerWaalsContact O-N 3.13Å; W478-R480 HydrophobicContact CD2-CB 4.05Å; W478-R480 HydrophobicContact CG-CB 4.46Å; W478-R480 HydrophobicContact CZ2-CB 4Å; W478-R480 HydrophobicContact CZ2-CG 4.43Å; W478-R480 PolarHBondContact O-N 3.44Å; W478-T481 HydrophobicContact CB-CG2 4.15Å; W478-T481 HydrophobicContact CD2-CG2 4.13Å; W478-T481 HydrophobicContact CE3-CG2 3.47Å; W478-T481 VanDerWaalsContact CE3-CG2 3.47Å; W478-T481 HydrophobicContact CG-CG2 4.44Å; W478-T481 HydrophobicContact CZ3-CG2 4.24Å; W478-T481 PolarHBondContact O-N 3.26Å; W478-T481 PolarHBondContact O-OG1 3.37Å; W478-S544 PolarHBondContact NE1-OG 2.79Å; W478-L547 HydrophobicContact CB-CD1 4.07Å; W478-L547 HydrophobicContact CD2-CB 4.23Å; W478-L547 HydrophobicContact CD2-CD1 3.97Å; W478-L547 HydrophobicContact CG-CD1 3.62Å; W478-L547 HydrophobicContact CH2-CB 4.45Å; W478-L547 HydrophobicContact CZ2-CB 3.79Å; W478-N548 WeakPolarHBondContact CZ2-OD1 3.39Å; W478-V551 HydrophobicContact CH2-CB 4.21Å; W478-V551 HydrophobicContact CH2-CG1 4.4Å; W478-V551 HydrophobicContact CH2-CG2 4.16Å; W478-V551 HydrophobicContact CZ3-CB 4.38Å; W478-V551 HydrophobicContact CZ3-CG1 4.18Å; W478-V551 HydrophobicContact CZ3-CG2 4.16Å; W478-V560 HydrophobicContact CH2-CG2 4.39Å; W478-V560 HydrophobicContact CZ3-CG2 3.98Å
479P94.3Very high81.1Confident57 Ų5754.6 Ų54.637%0.3727%0.266SS..G310 helixtrans-60.2-27.5-171.6-28.237.5000114.3F477 T481 R482F477-P479 WeakPolarHBondContact O-CD 2.94Å; P479-T481 PolarHBondContact O-N 2.89Å; P479-R482 WeakPolarHBondContact O-CB 3.37Å; P479-R482 PolarHBondContact O-N 2.83Å
480R93.9Very high78.4Confident115 Ų11563 Ų6343%0.43431%0.305SS..G310 helixtrans-68.6-16.6179.5-166.1173.3175.3-171.9-5.9113.8W478 N548 V560W478-R480 HydrophobicContact CD2-CB 4.05Å; W478-R480 HydrophobicContact CG-CB 4.46Å; W478-R480 HydrophobicContact CZ2-CB 4Å; W478-R480 HydrophobicContact CZ2-CG 4.43Å; W478-R480 PolarHBondContact O-N 3.44Å; R480-N548 VanDerWaalsContact CD-OD1 3.24Å; R480-N548 WeakPolarHBondContact CD-OD1 3.31Å; R480-N548 PolarHBondContact NH1-OD1 2.82Å; R480-V560 HydrophobicContact CG-CG1 4.13Å; R480-V560 HydrophobicContact CG-CG2 4.07Å
481T92.4Very high75.5Confident7 Ų770.4 Ų70.44%0.04335%0.345CS..G310 helixtrans-89.8-5.1178.964.20000113.3L475 W478 P479 T559 V560 K562L475-T481 HydrophobicContact CB-CG2 4.22Å; L475-T481 PolarHBondContact O-OG1 2.84Å; L475-T481 VanDerWaalsContact O-OG1 3.06Å; W478-T481 HydrophobicContact CB-CG2 4.15Å; W478-T481 HydrophobicContact CD2-CG2 4.13Å; W478-T481 HydrophobicContact CE3-CG2 3.47Å; W478-T481 VanDerWaalsContact CE3-CG2 3.47Å; W478-T481 HydrophobicContact CG-CG2 4.44Å; W478-T481 HydrophobicContact CZ3-CG2 4.24Å; W478-T481 PolarHBondContact O-N 3.26Å; W478-T481 PolarHBondContact O-OG1 3.37Å; P479-T481 PolarHBondContact O-N 2.89Å; T481-T559 WeakPolarHBondContact CB-O 3.27Å; T481-V560 HydrophobicContact CG2-CG2 4.18Å; T481-K562 PolarHBondContact O-NZ 3.48Å
482R86.8Confident72.6Confident92 Ų9278.7 Ų78.735%0.34738%0.383SS..PPolyproline II helixtrans-82.4132.1-179.9-61.9-177.8-172.4175.57.5109.9P479 V505P479-R482 WeakPolarHBondContact O-CB 3.37Å; P479-R482 PolarHBondContact O-N 2.83Å; R482-V505 HydrophobicContact CB-CG1 3.66Å; R482-V505 HydrophobicContact CG-CG1 4.06Å
483I69.1Low69.6Low49 Ų4983.8 Ų83.825%0.25142%0.416SS..PPolyproline II helixtrans-85.7126.5173.2-57.5172.6000107.7K562I483-K562 HydrophobicContact CD1-CG 4.17Å
484N58.8Low66.6Low98 Ų9890 Ų9052%0.52445%0.448SS..PPolyproline II helixtrans-80.3131.2167.6-83-19000108.4M486 D487N484-M486 PolarHBondContact O-N 2.84Å; N484-D487 PolarHBondContact O-N 3.3Å
485P48.2Very low63.6Low51 Ų5198.8 Ų98.833%0.33149%0.489SS..G310 helixtrans-63.3-7.6-179.321.6-30.3000114.6N503P485-N503 HydrophobicContact CG-CB 4.27Å
486M47.9Very low60.7Low149 Ų149103.4 Ų103.473%0.73453%0.528SS*.G310 helixtrans-81.1-15.6176-63.4-162.497.400114.2N484 E488N484-M486 PolarHBondContact O-N 2.84Å; M486-E488 VanDerWaalsContact C-N 3.32Å
487D49.2Very low57.7Low132 Ų132109.1 Ų109.171%0.70656%0.563SS**G310 helixtrans-84.5-5.3-179.4-66-35.4000112.9N484N484-D487 PolarHBondContact O-N 3.3Å
488E45.6Very low54.6Low131 Ų131113.9 Ų113.961%0.61259%0.592SS**SBendtrans-92.4-16.8175.9-71.9-175.5167.600113.4M486 E490 N491M486-E488 VanDerWaalsContact C-N 3.32Å; E488-E490 VanDerWaalsContact C-N 3.26Å; E488-E490 PolarHBondContact O-N 3Å; E488-N491 PolarHBondContact O-N 3.4Å
489E41.6Very low51.4Low153 Ų153117.1 Ų117.172%0.71563%0.625SS**THydrogen-bonded Turntrans-73-9.1-176.6-75.3-171.4166.700114.5N491E489-N491 VanDerWaalsContact C-N 3.34Å
490E40.3Very low48.6Very low186 Ų186124.4 Ų124.487%0.86965%0.654SS**THydrogen-bonded Turntrans-81.3-6.1176-79.2-166.4162.800114.4E488E488-E490 VanDerWaalsContact C-N 3.26Å; E488-E490 PolarHBondContact O-N 3Å
491N38.2Very low45.9Very low156 Ų156127.4 Ų127.483%0.83467%0.673SS**SBendtrans-120-2.3-176.7-85.8-34.3000117.4E488 E489E488-N491 PolarHBondContact O-N 3.4Å; E489-N491 VanDerWaalsContact C-N 3.34Å
492E36.5Very low43.2Very low176 Ų176134.4 Ų134.482%0.82271%0.705SS**  trans-132.495173.1-72.2-166.4167.100112.3
493V35.1Very low41Very low129 Ų129136.2 Ų136.278%0.78272%0.722SS**  trans-77.2120.5165.1-174.60000108.3
494N34.6Very low40.3Very low129 Ų129144 Ų14469%0.6975%0.748SS**  trans96.893.5167.3-55.1-39.3000117.4
495H34.8Very low40.4Very low187 Ų187141.8 Ų141.887%0.86674%0.738SS**  178.4107.697.6-95.3-67.1000110.4
496A38.7Very low41.3Very low100 Ų100145 Ų14583%0.82675%0.748SS**  trans-82.3123169.900000110.7
497V32.4Very low42.8Very low131 Ų131143.3 Ų143.379%0.79474%0.737SS**  trans-147.9113.4148.5-174.10000110.5
498N32.5Very low44.6Very low164 Ų164137.5 Ų137.588%0.87771%0.709SS**  trans16.5124.4153.7-64.7-15.7000121.1
499G29Very low46.8Very low67 Ų67131.9 Ų131.969%0.69168%0.682SS**  trans168.9128.8151.600000110.6Q501G499-Q501 PolarHBondContact O-N 3.29Å
500E36Very low49.1Very low211 Ų211127.6 Ų127.699%0.98668%0.68SS**  trans-52.199.4178.4-62.2174155.200111.5
501Q35.3Very low51.7Low177 Ų177123.1 Ų123.183%0.82766%0.656SS**  trans-111.2107.4172.9-122.6167.2700107.6G499 N503G499-Q501 PolarHBondContact O-N 3.29Å; Q501-N503 PolarHBondContact O-N 3.08Å
502E35.7Very low54.4Low154 Ų154116.6 Ų116.672%0.7262%0.62SS**  trans-51.7113.3165.3-75-176.8150.200108.4R504E502-R504 VanDerWaalsContact C-N 3.26Å; E502-R504 PolarHBondContact O-N 2.99Å
503N40.7Very low57.3Low130 Ų130114.3 Ų114.370%0.69561%0.609SS**  trans-56.783.3174.4-87.2-26.3000110.9P485 Q501 V505P485-N503 HydrophobicContact CG-CB 4.27Å; Q501-N503 PolarHBondContact O-N 3.08Å; N503-V505 PolarHBondContact O-N 2.86Å; N503-V505 VanDerWaalsContact O-N 3.11Å
504R55.3Low60.3Low214 Ų214108.4 Ų108.481%0.80857%0.573SS**  trans-79.693.8175.3-75-175.4-179.8-177.81.6108.7E502 Q506E502-R504 VanDerWaalsContact C-N 3.26Å; E502-R504 PolarHBondContact O-N 2.99Å; R504-Q506 PolarHBondContact O-N 2.87Å
505V61.9Low63.4Low51 Ų51103.7 Ų103.731%0.30955%0.55SS..  trans-41.9115.8164.8174.90000109.2R482 N503 K507R482-V505 HydrophobicContact CB-CG1 3.66Å; R482-V505 HydrophobicContact CG-CG1 4.06Å; N503-V505 PolarHBondContact O-N 2.86Å; N503-V505 VanDerWaalsContact O-N 3.11Å; V505-K507 PolarHBondContact O-N 2.82Å; V505-K507 VanDerWaalsContact O-N 3.14Å
506Q66.1Low66.4Low118 Ų11897.6 Ų97.655%0.55153%0.527SS*.  trans-66.2115.7-178.9-166.4171.315.300108.9R504R504-Q506 PolarHBondContact O-N 2.87Å
507K78.6Confident69.2Low113 Ų11394.4 Ų94.449%0.49150%0.495SS..  trans-104.7138.2179.3-69.1179.3-175.5174.90109.9E476 V505E476-K507 HydrophobicContact CG-CB 4.4Å; V505-K507 PolarHBondContact O-N 2.82Å; V505-K507 VanDerWaalsContact O-N 3.14Å
508G87.1Confident72.4Confident11 Ų1188.3 Ų88.311%0.11346%0.458CS..THydrogen-bonded Turntrans69.1-144.9175.900000112.8
509N92.3Very high75.6Confident12 Ų1280.6 Ų80.66%0.06442%0.416CS..THydrogen-bonded Turntrans-104.7-7.3-173.767.138.3000114.6L469 Q472 Y511 F512L469-N509 HydrophobicContact CB-CB 4.41Å; L469-N509 HydrophobicContact CD2-CB 3.72Å; L469-N509 PolarHBondContact O-ND2 2.82Å; Q472-N509 HydrophobicContact CB-CB 3.89Å; Q472-N509 VanDerWaalsContact OE1-CB 3.24Å; N509-Y511 VanDerWaalsContact C-N 3.33Å; N509-Y511 WeakPolarHBondContact O-CD2 3.5Å; N509-Y511 PolarHBondContact O-N 2.95Å; N509-Y511 WeakPolarHBondContact OD1-CA 3.36Å; N509-Y511 PolarHBondContact OD1-N 2.87Å; N509-F512 VanDerWaalsContact ND2-CE1 3.34Å; N509-F512 WeakPolarHBondContact ND2-CE1 3.4Å; N509-F512 WeakPolarHBondContact ND2-CZ 3.24Å; N509-F512 PolarHBondContact ND2-O 2.89Å; N509-F512 PolarHBondContact OD1-N 2.82Å; N509-F512 PolarHBondContact OD1-O 2.82Å
510G91.1Very high78.9Confident64 Ų6477.4 Ų77.466%0.6638%0.383SS*.SBendtrans81.8-6.9-179.500000116.5
511Y93.3Very high81.9Confident92 Ų9268 Ų6836%0.36134%0.34SS..SBendtrans-111.2-40.9-176.9-63.7-84.9000113.6F454 L464 L469 N509F454-Y511 HydrophobicContact CB-CD1 3.88Å; F454-Y511 HydrophobicContact CB-CE1 4.38Å; F454-Y511 HydrophobicContact CD1-CD1 4.28Å; F454-Y511 HydrophobicContact CD2-CD1 4.14Å; F454-Y511 AromaticContact CG-CD1 3.86Å; F454-Y511 HydrophobicContact CG-CD1 3.86Å; F454-Y511 HydrophobicContact CG-CG 4.48Å; L464-Y511 HydrophobicContact CD1-CD1 4.28Å; L464-Y511 HydrophobicContact CD1-CE1 4.04Å; L464-Y511 HydrophobicContact CD2-CE1 4.18Å; L464-Y511 HydrophobicContact CD2-CE2 3.83Å; L464-Y511 WeakPolarHBondContact CD2-OH 3.36Å; L469-Y511 HydrophobicContact CD1-CD2 4.28Å; L469-Y511 HydrophobicContact CD2-CD2 3.74Å; L469-Y511 HydrophobicContact CD2-CE2 4.05Å; N509-Y511 VanDerWaalsContact C-N 3.33Å; N509-Y511 WeakPolarHBondContact O-CD2 3.5Å; N509-Y511 PolarHBondContact O-N 2.95Å; N509-Y511 WeakPolarHBondContact OD1-CA 3.36Å; N509-Y511 PolarHBondContact OD1-N 2.87Å
512F95.9Very high84.9Confident18 Ų1859.6 Ų59.68%0.07930%0.301CS..  trans-156.5163.9-178.967.9-88.7000111.9L394 K395 F454 L469 L470 A473 N509 V514L394-F512 HydrophobicContact CD1-CE1 3.76Å; L394-F512 HydrophobicContact CD1-CE2 4.39Å; L394-F512 HydrophobicContact CD1-CZ 3.46Å; L394-F512 VanDerWaalsContact CD1-CZ 3.46Å; L394-F512 HydrophobicContact CD2-CD1 4.31Å; L394-F512 HydrophobicContact CD2-CE1 3.78Å; L394-F512 HydrophobicContact CD2-CZ 4.25Å; L394-F512 HydrophobicContact CG-CD1 4.28Å; L394-F512 HydrophobicContact CG-CE1 3.54Å; L394-F512 HydrophobicContact CG-CE2 4.16Å; L394-F512 HydrophobicContact CG-CZ 3.48Å; L394-F512 VanDerWaalsContact CG-CZ 3.48Å; L394-F512 WeakPolarHBondContact O-CE2 3.38Å; K395-F512 HydrophobicContact CG-CB 4.23Å; K395-F512 HydrophobicContact CG-CD2 4.29Å; K395-F512 HydrophobicContact CG-CG 4.29Å; F454-F512 HydrophobicContact CE1-CB 4.43Å; F454-F512 HydrophobicContact CE1-CD1 4.31Å; F454-F512 HydrophobicContact CE2-CD1 4.47Å; F454-F512 AromaticContact CZ-CD1 3.68Å; F454-F512 HydrophobicContact CZ-CD1 3.68Å; F454-F512 HydrophobicContact CZ-CE1 4.39Å; F454-F512 HydrophobicContact CZ-CG 4.48Å; L469-F512 HydrophobicContact CB-CE1 3.77Å; L469-F512 HydrophobicContact CB-CZ 4.06Å; L469-F512 HydrophobicContact CD1-CE1 4.3Å; L470-F512 HydrophobicContact CD1-CE2 4.49Å; A473-F512 HydrophobicContact CB-CD2 4.2Å; A473-F512 HydrophobicContact CB-CE2 3.61Å; A473-F512 HydrophobicContact CB-CZ 4.25Å; N509-F512 VanDerWaalsContact ND2-CE1 3.34Å; N509-F512 WeakPolarHBondContact ND2-CE1 3.4Å; N509-F512 WeakPolarHBondContact ND2-CZ 3.24Å; N509-F512 PolarHBondContact ND2-O 2.89Å; N509-F512 PolarHBondContact OD1-N 2.82Å; N509-F512 PolarHBondContact OD1-O 2.82Å; F512-V514 HydrophobicContact CE2-CG1 4.37Å
513Q97.1Very high87.8Confident129 Ų12952.8 Ų52.860%0.60327%0.272SS*.  trans-118.8151.7170.8-59.6-177-38.500109.5E476E476-Q513 PolarHBondContact OE1-NE2 2.95Å; E476-Q513 WeakPolarHBondContact OE2-CG 3.34Å
514V98.4Very high90.3Very high5 Ų549 Ų493%0.0325%0.25CC..  trans-88.2155.7166.9-65.40000109.6A396 L470 A473 L474 F512 C535A396-V514 HydrophobicContact CB-CB 4.15Å; A396-V514 HydrophobicContact CB-CG1 3.87Å; L470-V514 HydrophobicContact CD1-CG1 4.06Å; A473-V514 HydrophobicContact CB-CG1 3.92Å; A473-V514 HydrophobicContact CB-CG2 4.44Å; L474-V514 HydrophobicContact CD2-CG1 4.31Å; L474-V514 HydrophobicContact CD2-CG2 4.31Å; F512-V514 HydrophobicContact CE2-CG1 4.37Å; V514-C535 HydrophobicContact CG2-CB 4.38Å
515P98.6Very high91.7Very high30 Ų3040.5 Ų40.520%0.19523%0.226CC..  trans-54.1129.7173.8-26.334.3000111K395 C397 H517 T518K395-P515 WeakPolarHBondContact O-CD 3.12Å; C397-P515 HydrophobicContact CB-CG 4.45Å; P515-H517 WeakPolarHBondContact CB-CE1 3.34Å; P515-H517 PolarHBondContact O-N 3.13Å; P515-H517 VanDerWaalsContact O-N 3.08Å; P515-T518 WeakPolarHBondContact O-CB 3.21Å; P515-T518 PolarHBondContact O-N 3.17Å; P515-T518 PolarHBondContact O-OG1 2.94Å
516P98.4Very high92.4Very high59 Ų5941.1 Ų41.138%0.38324%0.242SC..THydrogen-bonded Turntrans-63.4-22.2-171.9-22.931.9000114.2T518 R536P516-T518 VanDerWaalsContact C-N 3.28Å; P516-R536 HydrophobicContact CB-CB 3.83Å; P516-R536 HydrophobicContact CB-CG 4.46Å; P516-R536 WeakPolarHBondContact O-CB 3.26Å; P516-R536 WeakPolarHBondContact O-CG 3.46Å; P516-R536 PolarHBondContact O-N 3.28Å
517H98.6Very high93.1Very high33 Ų3336.9 Ų36.915%0.15323%0.23CC..THydrogen-bonded Turntrans-81.90.2174.866.9-89.5000114.1R22 E24 P515 P519R22-H517 PolarHBondContact O-NE2 2.89Å; E24-H517 WeakPolarHBondContact CA-CD2 3.47Å; E24-H517 HydrophobicContact CB-CB 3.98Å; E24-H517 HydrophobicContact CG-CB 3.8Å; E24-H517 PolarHBondContact N-CD2 2.83Å; E24-H517 PolarHBondContact N-NE2 3.27Å; P515-H517 WeakPolarHBondContact CB-CE1 3.34Å; P515-H517 PolarHBondContact O-N 3.13Å; P515-H517 VanDerWaalsContact O-N 3.08Å; H517-P519 VanDerWaalsContact O-CD 3.25Å; H517-P519 WeakPolarHBondContact O-CD 3.17Å
518T98.8Very high93.7Very high2 Ų235.4 Ų35.41%0.01222%0.221CC..  trans-60.9119.9179.8-610000109.8Y19 L474 P515 P516 V520 C535Y19-T518 HydrophobicContact CD2-CG2 3.89Å; Y19-T518 HydrophobicContact CG-CG2 4.32Å; L474-T518 HydrophobicContact CD2-CG2 4.36Å; P515-T518 WeakPolarHBondContact O-CB 3.21Å; P515-T518 PolarHBondContact O-N 3.17Å; P515-T518 PolarHBondContact O-OG1 2.94Å; P516-T518 VanDerWaalsContact C-N 3.28Å; T518-V520 PolarHBondContact O-N 3.24Å; T518-C535 PolarHBondContact O-N 3.06Å
519P98.8Very high94.1Very high2 Ų235.8 Ų35.81%0.01322%0.222CC..EExtended strand (participates in β ladder)trans-68.2130.1173.8-18.332.4000110.4Y19 V20 H517 L533 L534Y19-P519 WeakPolarHBondContact CA-O 3.42Å; Y19-P519 VanDerWaalsContact CB-O 3.29Å; Y19-P519 WeakPolarHBondContact CB-O 3.48Å; V20-P519 HydrophobicContact CB-CG 4.33Å; V20-P519 PolarHBondContact N-O 3.23Å; H517-P519 VanDerWaalsContact O-CD 3.25Å; H517-P519 WeakPolarHBondContact O-CD 3.17Å; P519-L533 CarbonylContact C-O 3.58Å; P519-L533 WeakPolarHBondContact CA-O 3.47Å; P519-L534 HydrophobicContact CB-CD2 4.3Å; P519-L534 HydrophobicContact CG-CD2 4.12Å
520V98.8Very high94.2Very high0 Ų036.9 Ų36.90%023%0.227CC..EExtended strand (participates in β ladder)trans-109.7132172.9-173.70000108.3V17 L474 T518 F522 R532 L533 C535V17-V520 HydrophobicContact CG1-CG1 4.2Å; L474-V520 HydrophobicContact CB-CG2 4.27Å; L474-V520 HydrophobicContact CD2-CG2 4.08Å; T518-V520 PolarHBondContact O-N 3.24Å; V520-F522 HydrophobicContact CG1-CE2 3.88Å; V520-F522 HydrophobicContact CG1-CZ 4Å; V520-R532 WeakPolarHBondContact O-CA 3.45Å; V520-L533 HydrophobicContact CB-CD2 3.96Å; V520-L533 HydrophobicContact CG1-CD2 4.45Å; V520-L533 PolarHBondContact N-O 3Å; V520-L533 PolarHBondContact O-N 2.75Å; V520-C535 HydrophobicContact CG2-CB 4.3Å
521I98.8Very high94.5Very high15 Ų1535 Ų358%0.07720%0.201CC..EExtended strand (participates in β ladder)trans-129.4126-171.4-58.4163.3000109V17 S18 V20 T75 T529 R532V17-I521 CarbonylContact C-O 3.5Å; V17-I521 WeakPolarHBondContact CA-O 3.45Å; S18-I521 PolarHBondContact N-O 3.26Å; S18-I521 PolarHBondContact O-N 3.46Å; V20-I521 HydrophobicContact CG2-CD1 4.27Å; T75-I521 HydrophobicContact CG2-CD1 3.79Å; T75-I521 HydrophobicContact CG2-CG1 3.97Å; T75-I521 HydrophobicContact CG2-CG2 3.83Å; I521-T529 HydrophobicContact CG2-CG2 4.07Å; I521-R532 HydrophobicContact CG1-CB 4.44Å; I521-R532 HydrophobicContact CG1-CG 4.07Å
522F98.4Very high94.8Very high0 Ų032.4 Ų32.40%019%0.191CC..EExtended strand (participates in β ladder)trans-104.6122169.8-60.5-85.8000108.6V15 V17 L475 V520 L530 F531 L533 L547 V551V15-F522 HydrophobicContact CG1-CB 4.39Å; V17-F522 HydrophobicContact CG1-CE1 4.22Å; V17-F522 HydrophobicContact CG2-CD1 3.94Å; V17-F522 HydrophobicContact CG2-CE1 3.72Å; L475-F522 HydrophobicContact CD1-CZ 4.49Å; L475-F522 HydrophobicContact CD2-CZ 4.16Å; V520-F522 HydrophobicContact CG1-CE2 3.88Å; V520-F522 HydrophobicContact CG1-CZ 4Å; F522-L530 WeakPolarHBondContact O-CA 3.37Å; F522-L530 WeakPolarHBondContact O-CB 3.2Å; F522-L530 PolarHBondContact O-N 3.37Å; F522-F531 HydrophobicContact CD2-CB 4.44Å; F522-F531 HydrophobicContact CD2-CD1 4.2Å; F522-F531 PolarHBondContact N-O 3.27Å; F522-F531 PolarHBondContact O-N 2.7Å; F522-L533 HydrophobicContact CE2-CD2 4.03Å; F522-L547 HydrophobicContact CD2-CD2 4.46Å; F522-L547 HydrophobicContact CE2-CD2 3.6Å; F522-L547 HydrophobicContact CZ-CD2 4.01Å; F522-V551 HydrophobicContact CE1-CB 4.46Å; F522-V551 HydrophobicContact CE1-CG1 4.48Å; F522-V551 HydrophobicContact CE1-CG2 3.85Å; F522-V551 HydrophobicContact CE2-CG2 4.33Å; F522-V551 HydrophobicContact CZ-CG2 3.75Å
523G96.2Very high94.9Very high11 Ų1132 Ų3211%0.11319%0.189CC..EExtended strand (participates in β ladder)trans-145.3152.7-175.300000113.1V15 Q16 R528V15-G523 CarbonylContact C-O 3.58Å; V15-G523 WeakPolarHBondContact CA-O 3.42Å; Q16-G523 PolarHBondContact N-O 2.76Å; Q16-G523 PolarHBondContact O-N 2.87Å; Q16-G523 VanDerWaalsContact O-N 3.12Å; G523-R528 CarbonylContact C-O 3.58Å; G523-R528 WeakPolarHBondContact CA-O 3.38Å
524E94.1Very high95Very high49 Ų4927.3 Ų27.323%0.22917%0.168CC..EExtended strand (participates in β ladder)trans-75.3140.1172.3-66.517917400110.7R13 G526 G527 R528 L530R13-E524 HydrophobicContact CB-CB 4.01Å; R13-E524 HydrophobicContact CB-CG 4.3Å; E524-G526 PolarHBondContact O-N 3.03Å; E524-G527 PolarHBondContact O-N 2.83Å; E524-R528 HydrophobicContact CB-CB 4.41Å; E524-R528 PolarHBondContact N-O 2.9Å; E524-L530 HydrophobicContact CG-CD1 4.29Å; E524-L530 HydrophobicContact CG-CD2 4.16Å; E524-L530 HydrophobicContact CG-CG 4.34Å
525A84.8Confident95Very high37 Ų3727.1 Ų27.131%0.30617%0.167SC..THydrogen-bonded Turntrans-55.3109.1167.900000109.3R13 K14 Q16R13-A525 WeakPolarHBondContact CD-O 3.32Å; K14-A525 PolarHBondContact O-N 3.05Å; Q16-A525 HydrophobicContact CG-CB 4.47Å
526G77Confident94.9Very high63 Ų6330.3 Ų30.365%0.64918%0.175SC*.THydrogen-bonded Turntrans111.810.1-173.500000115.9E524E524-G526 PolarHBondContact O-N 3.03Å
527G80.5Confident94.9Very high29 Ų2930.6 Ų30.630%0.29917%0.173SC..SBendtrans116.1-10.8150.100000117.3E524 T529E524-G527 PolarHBondContact O-N 2.83Å; G527-T529 PolarHBondContact O-N 2.9Å
528R90.8Very high94.8Very high82 Ų8229 Ų2931%0.30917%0.166SC..  trans-78.8117.4178.5-174179.8176.4112.3-8.9110.3R114 G523 E524R114-R528 PolarHBondContact O-NH1 3.46Å; G523-R528 CarbonylContact C-O 3.58Å; G523-R528 WeakPolarHBondContact CA-O 3.38Å; E524-R528 HydrophobicContact CB-CB 4.41Å; E524-R528 PolarHBondContact N-O 2.9Å
529T95.4Very high94.5Very high19 Ų1930.9 Ų30.912%0.11719%0.186CC..EExtended strand (participates in β ladder)trans-79.3126.5173.1-63.80000111T75 I521 G527T75-T529 HydrophobicContact CG2-CG2 3.79Å; T75-T529 PolarHBondContact OG1-OG1 2.91Å; I521-T529 HydrophobicContact CG2-CG2 4.07Å; G527-T529 PolarHBondContact O-N 2.9Å
530L95.4Very high94.4Very high36 Ų3632 Ų3219%0.18820%0.198CC..EExtended strand (participates in β ladder)trans-88.7-49.7178.8-58.8179.2000110.9V15 R114 F522 E524 T550V15-L530 HydrophobicContact CG1-CD1 4.07Å; V15-L530 HydrophobicContact CG2-CD1 3.75Å; R114-L530 PolarHBondContact NH2-O 2.91Å; F522-L530 WeakPolarHBondContact O-CA 3.37Å; F522-L530 WeakPolarHBondContact O-CB 3.2Å; F522-L530 PolarHBondContact O-N 3.37Å; E524-L530 HydrophobicContact CG-CD1 4.29Å; E524-L530 HydrophobicContact CG-CD2 4.16Å; E524-L530 HydrophobicContact CG-CG 4.34Å; L530-T550 HydrophobicContact CB-CG2 4.36Å
531F97.4Very high94.2Very high24 Ų2440.6 Ų40.611%0.10524%0.238CC..EExtended strand (participates in β ladder)trans-153.2148.2-178.4-175.7-134.2000111.5F522 L533 E543 L546 L547 T550F522-F531 HydrophobicContact CD2-CB 4.44Å; F522-F531 HydrophobicContact CD2-CD1 4.2Å; F522-F531 PolarHBondContact N-O 3.27Å; F522-F531 PolarHBondContact O-N 2.7Å; F531-L533 HydrophobicContact CD1-CD2 4.07Å; F531-L533 HydrophobicContact CE1-CB 4.13Å; F531-L533 HydrophobicContact CE1-CD1 3.91Å; F531-L533 HydrophobicContact CE1-CD2 3.73Å; F531-L533 HydrophobicContact CE1-CG 4.13Å; F531-L533 HydrophobicContact CZ-CB 3.89Å; F531-L533 HydrophobicContact CZ-CD1 4.21Å; F531-L533 HydrophobicContact CZ-CD2 4.36Å; F531-L533 HydrophobicContact CZ-CG 4.38Å; F531-E543 HydrophobicContact CZ-CB 4.32Å; F531-E543 HydrophobicContact CZ-CG 4.32Å; F531-L546 HydrophobicContact CD1-CB 4.14Å; F531-L546 HydrophobicContact CD2-CB 4.13Å; F531-L546 HydrophobicContact CD2-CD1 3.92Å; F531-L546 HydrophobicContact CE1-CB 3.89Å; F531-L546 HydrophobicContact CE2-CB 3.92Å; F531-L546 HydrophobicContact CE2-CD1 3.42Å; F531-L546 VanDerWaalsContact CE2-CD1 3.42Å; F531-L546 HydrophobicContact CE2-CG 4.3Å; F531-L546 HydrophobicContact CG-CB 4.26Å; F531-L546 HydrophobicContact CZ-CB 3.8Å; F531-L546 HydrophobicContact CZ-CD1 3.94Å; F531-L547 HydrophobicContact CD1-CD2 4.14Å; F531-L547 HydrophobicContact CE1-CD2 3.93Å; F531-L547 HydrophobicContact CE1-CG 3.99Å; F531-T550 HydrophobicContact CB-CG2 4.05Å
532R98.3Very high94Very high38 Ų3843.9 Ų43.914%0.14326%0.259CS..EExtended strand (participates in β ladder)trans-140.6133.3176.3175.7-171-179.3-825.5108E72 H73 T75 V520 I521E72-R532 IonicContact OE2-NH2 2.91Å; E72-R532 PolarHBondContact OE2-NH2 2.92Å; H73-R532 WeakPolarHBondContact O-CD 3.44Å; T75-R532 HydrophobicContact CG2-CB 4.44Å; V520-R532 WeakPolarHBondContact O-CA 3.45Å; I521-R532 HydrophobicContact CG1-CB 4.44Å; I521-R532 HydrophobicContact CG1-CG 4.07Å
533L98.5Very high93.9Very high8 Ų847 Ų474%0.04227%0.273CS..EExtended strand (participates in β ladder)trans-145.3169.7172.972.5172.1000110.2P519 V520 F522 F531 S538 E543 L547P519-L533 CarbonylContact C-O 3.58Å; P519-L533 WeakPolarHBondContact CA-O 3.47Å; V520-L533 HydrophobicContact CB-CD2 3.96Å; V520-L533 HydrophobicContact CG1-CD2 4.45Å; V520-L533 PolarHBondContact N-O 3Å; V520-L533 PolarHBondContact O-N 2.75Å; F522-L533 HydrophobicContact CE2-CD2 4.03Å; F531-L533 HydrophobicContact CD1-CD2 4.07Å; F531-L533 HydrophobicContact CE1-CB 4.13Å; F531-L533 HydrophobicContact CE1-CD1 3.91Å; F531-L533 HydrophobicContact CE1-CD2 3.73Å; F531-L533 HydrophobicContact CE1-CG 4.13Å; F531-L533 HydrophobicContact CZ-CB 3.89Å; F531-L533 HydrophobicContact CZ-CD1 4.21Å; F531-L533 HydrophobicContact CZ-CD2 4.36Å; F531-L533 HydrophobicContact CZ-CG 4.38Å; L533-S538 WeakPolarHBondContact CD1-OG 3.32Å; L533-E543 HydrophobicContact CD1-CB 4.3Å; L533-L547 HydrophobicContact CD1-CD1 4.07Å; L533-L547 HydrophobicContact CD1-CD2 4.25Å; L533-L547 HydrophobicContact CD1-CG 4.33Å; L533-L547 HydrophobicContact CD2-CD2 4.24Å
534L98.6Very high93.8Very high32 Ų3247.6 Ų47.617%0.16828%0.276CS..EExtended strand (participates in β ladder)trans-86.4148.8162.8-50.2-177.9000109P519 R536 D537P519-L534 HydrophobicContact CB-CD2 4.3Å; P519-L534 HydrophobicContact CG-CD2 4.12Å; L534-R536 VanDerWaalsContact C-N 3.26Å; L534-R536 HydrophobicContact CB-CG 4.32Å; L534-R536 PolarHBondContact O-N 2.93Å; L534-D537 WeakPolarHBondContact CB-OD2 3.43Å; L534-D537 WeakPolarHBondContact CG-OD2 3.44Å; L534-D537 PolarHBondContact O-N 2.88Å
535C98.3Very high93.9Very high0 Ų050 Ų500%029%0.288CS..G310 helixtrans-48.3-47.6-179.91790000112.4L474 F477 V514 T518 V520 D537 S538L474-C535 PolarHBondContact O-SG 3.15Å; F477-C535 WeakPolarHBondContact CD2-O 3.44Å; V514-C535 HydrophobicContact CG2-CB 4.38Å; T518-C535 PolarHBondContact O-N 3.06Å; V520-C535 HydrophobicContact CG2-CB 4.3Å; C535-D537 VanDerWaalsContact C-N 3.26Å; C535-D537 PolarHBondContact O-N 2.93Å; C535-S538 PolarHBondContact O-N 2.86Å; C535-S538 PolarHBondContact O-OG 3Å
536R97.9Very high94.5Very high97 Ų9750.6 Ų50.637%0.36629%0.286SS..G310 helixtrans-62.7-23.9179.567-173.7163.7-162.2-8.4115.7E24 P516 L534 S538E24-R536 IonicContact OE1-CZ 3.05Å; E24-R536 IonicContact OE1-NH1 3.1Å; E24-R536 PolarHBondContact OE1-NH1 3.23Å; E24-R536 IonicContact OE1-NH2 3.99Å; E24-R536 PolarHBondContact OE1-NH2 2.97Å; P516-R536 HydrophobicContact CB-CB 3.83Å; P516-R536 HydrophobicContact CB-CG 4.46Å; P516-R536 WeakPolarHBondContact O-CB 3.26Å; P516-R536 WeakPolarHBondContact O-CG 3.46Å; P516-R536 PolarHBondContact O-N 3.28Å; L534-R536 VanDerWaalsContact C-N 3.26Å; L534-R536 HydrophobicContact CB-CG 4.32Å; L534-R536 PolarHBondContact O-N 2.93Å; R536-S538 VanDerWaalsContact C-N 3.3Å; R536-S538 PolarHBondContact O-N 2.94Å
537D97.8Very high95.4Very high66 Ų6647.6 Ų47.635%0.35326%0.255SS..G310 helixtrans-85.3-6.1-173.4-59.5-29.3000112.4L534 C535 G539 G540 E543L534-D537 WeakPolarHBondContact CB-OD2 3.43Å; L534-D537 WeakPolarHBondContact CG-OD2 3.44Å; L534-D537 PolarHBondContact O-N 2.88Å; C535-D537 VanDerWaalsContact C-N 3.26Å; C535-D537 PolarHBondContact O-N 2.93Å; D537-G539 PolarHBondContact O-N 3.49Å; D537-G540 PolarHBondContact O-N 2.98Å; D537-E543 HydrophobicContact CB-CG 4.36Å; D537-E543 WeakPolarHBondContact O-CB 3.31Å; D537-E543 WeakPolarHBondContact O-CG 3.36Å
538S96.3Very high96.2Very high0 Ų049.6 Ų49.60%026%0.259CS..G310 helixtrans-59.1-14-177.1-50.30000114.8L533 C535 R536L533-S538 WeakPolarHBondContact CD1-OG 3.32Å; C535-S538 PolarHBondContact O-N 2.86Å; C535-S538 PolarHBondContact O-OG 3Å; R536-S538 VanDerWaalsContact C-N 3.3Å; R536-S538 PolarHBondContact O-N 2.94Å
539G93.6Very high96.4Very high41 Ų4152.4 Ų52.442%0.42328%0.276SS..G310 helixtrans-84.3-12.7176.200000115.6D537D537-G539 PolarHBondContact O-N 3.49Å
540G95.2Very high96.4Very high26 Ų2652.7 Ų52.727%0.26828%0.277SS..SBendtrans-67150.9178.900000112.4D537 T542 E543 S544D537-G540 PolarHBondContact O-N 2.98Å; G540-T542 PolarHBondContact O-N 2.93Å; G540-E543 WeakPolarHBondContact CA-OE2 3.33Å; G540-E543 PolarHBondContact O-N 2.75Å; G540-S544 WeakPolarHBondContact O-CB 3.36Å; G540-S544 PolarHBondContact O-N 2.67Å
541E95.3Very high96.5Very high179 Ų17951.4 Ų51.484%0.83627%0.271SS*.Hα-helixtrans-62.3-45.5-176.9-173.9-179.8-177.600111.7M545E541-M545 WeakPolarHBondContact O-CB 3.45Å; E541-M545 PolarHBondContact O-N 2.86Å
542T93.7Very high96.5Very high85 Ų8551.3 Ų51.352%0.52127%0.272SS..Hα-helixtrans-68.7-43.8179.1-60.60000110.9G540 M545 L546G540-T542 PolarHBondContact O-N 2.93Å; T542-M545 PolarHBondContact O-N 2.94Å; T542-L546 HydrophobicContact CG2-CD1 4.04Å; T542-L546 WeakPolarHBondContact O-CG 3.3Å; T542-L546 PolarHBondContact O-N 2.99Å
543E96.3Very high96.4Very high65 Ų6554.7 Ų54.730%0.30429%0.29SS..Hα-helixtrans-63.3-46178.9-68.773.7-164.800111.1F531 L533 D537 G540 M545 L546 L547F531-E543 HydrophobicContact CZ-CB 4.32Å; F531-E543 HydrophobicContact CZ-CG 4.32Å; L533-E543 HydrophobicContact CD1-CB 4.3Å; D537-E543 HydrophobicContact CB-CG 4.36Å; D537-E543 WeakPolarHBondContact O-CB 3.31Å; D537-E543 WeakPolarHBondContact O-CG 3.36Å; G540-E543 WeakPolarHBondContact CA-OE2 3.33Å; G540-E543 PolarHBondContact O-N 2.75Å; E543-M545 PolarHBondContact O-N 3.46Å; E543-L546 PolarHBondContact O-N 2.92Å; E543-L547 WeakPolarHBondContact O-CB 3.23Å; E543-L547 VanDerWaalsContact O-CG 3.3Å; E543-L547 WeakPolarHBondContact O-CG 3.48Å; E543-L547 PolarHBondContact O-N 2.92Å
544S95.4Very high96.3Very high23 Ų2355.1 Ų55.116%0.16129%0.291CS..Hα-helixtrans-63.6-40.3178-173.50000111.8W478 G540 L547 N548W478-S544 PolarHBondContact NE1-OG 2.79Å; G540-S544 WeakPolarHBondContact O-CB 3.36Å; G540-S544 PolarHBondContact O-N 2.67Å; S544-L547 PolarHBondContact O-N 2.88Å; S544-N548 PolarHBondContact O-N 2.77Å; S544-N548 PolarHBondContact O-ND2 3.1Å
545M96.3Very high96.3Very high101 Ų10153.6 Ų53.650%0.49828%0.283SS..Hα-helixtrans-59.6-47.6172.5-174.1-173.777.200111.2E541 T542 E543 L547 N548 E549E541-M545 WeakPolarHBondContact O-CB 3.45Å; E541-M545 PolarHBondContact O-N 2.86Å; T542-M545 PolarHBondContact O-N 2.94Å; E543-M545 PolarHBondContact O-N 3.46Å; M545-L547 PolarHBondContact O-N 2.94Å; M545-N548 WeakPolarHBondContact O-CB 3.39Å; M545-N548 PolarHBondContact O-N 3.45Å; M545-E549 PolarHBondContact O-N 2.78Å
546L95.8Very high96.2Very high49 Ų4954.2 Ų54.226%0.25729%0.286SS..Hα-helixtrans-66.3-35.8178.4-70.2170000112.5F531 T542 E543 E549 T550F531-L546 HydrophobicContact CD1-CB 4.14Å; F531-L546 HydrophobicContact CD2-CB 4.13Å; F531-L546 HydrophobicContact CD2-CD1 3.92Å; F531-L546 HydrophobicContact CE1-CB 3.89Å; F531-L546 HydrophobicContact CE2-CB 3.92Å; F531-L546 HydrophobicContact CE2-CD1 3.42Å; F531-L546 VanDerWaalsContact CE2-CD1 3.42Å; F531-L546 HydrophobicContact CE2-CG 4.3Å; F531-L546 HydrophobicContact CG-CB 4.26Å; F531-L546 HydrophobicContact CZ-CB 3.8Å; F531-L546 HydrophobicContact CZ-CD1 3.94Å; T542-L546 HydrophobicContact CG2-CD1 4.04Å; T542-L546 WeakPolarHBondContact O-CG 3.3Å; T542-L546 PolarHBondContact O-N 2.99Å; E543-L546 PolarHBondContact O-N 2.92Å; L546-E549 PolarHBondContact O-N 2.94Å; L546-T550 WeakPolarHBondContact O-CB 3.38Å; L546-T550 WeakPolarHBondContact O-CG2 3.26Å; L546-T550 PolarHBondContact O-N 3.49Å; L546-T550 PolarHBondContact O-OG1 2.85Å
547L97.6Very high96.1Very high0 Ų052.2 Ų52.20%028%0.283CS..Hα-helixtrans-61.7-43.6172.9-73.3171.4000111L475 W478 F522 F531 L533 E543 S544 M545 E549 T550 V551L475-L547 HydrophobicContact CD2-CD1 4.41Å; L475-L547 HydrophobicContact CD2-CD2 4.02Å; W478-L547 HydrophobicContact CB-CD1 4.07Å; W478-L547 HydrophobicContact CD2-CB 4.23Å; W478-L547 HydrophobicContact CD2-CD1 3.97Å; W478-L547 HydrophobicContact CG-CD1 3.62Å; W478-L547 HydrophobicContact CH2-CB 4.45Å; W478-L547 HydrophobicContact CZ2-CB 3.79Å; F522-L547 HydrophobicContact CD2-CD2 4.46Å; F522-L547 HydrophobicContact CE2-CD2 3.6Å; F522-L547 HydrophobicContact CZ-CD2 4.01Å; F531-L547 HydrophobicContact CD1-CD2 4.14Å; F531-L547 HydrophobicContact CE1-CD2 3.93Å; F531-L547 HydrophobicContact CE1-CG 3.99Å; L533-L547 HydrophobicContact CD1-CD1 4.07Å; L533-L547 HydrophobicContact CD1-CD2 4.25Å; L533-L547 HydrophobicContact CD1-CG 4.33Å; L533-L547 HydrophobicContact CD2-CD2 4.24Å; E543-L547 WeakPolarHBondContact O-CB 3.23Å; E543-L547 VanDerWaalsContact O-CG 3.3Å; E543-L547 WeakPolarHBondContact O-CG 3.48Å; E543-L547 PolarHBondContact O-N 2.92Å; S544-L547 PolarHBondContact O-N 2.88Å; M545-L547 PolarHBondContact O-N 2.94Å; L547-E549 PolarHBondContact O-N 3.07Å; L547-T550 PolarHBondContact O-N 3.46Å; L547-V551 HydrophobicContact CB-CG2 3.99Å; L547-V551 HydrophobicContact CD2-CG2 3.65Å; L547-V551 HydrophobicContact CG-CG2 4.44Å; L547-V551 VanDerWaalsContact O-CB 3.3Å; L547-V551 WeakPolarHBondContact O-CB 3.45Å; L547-V551 WeakPolarHBondContact O-CG2 3.46Å; L547-V551 PolarHBondContact O-N 3.01Å
548N96.3Very high96Very high71 Ų7149.3 Ų49.338%0.3827%0.267SS..Hα-helixtrans-59.3-31175.8-74.6-51.6000113.1W478 R480 S544 M545W478-N548 WeakPolarHBondContact CZ2-OD1 3.39Å; R480-N548 VanDerWaalsContact CD-OD1 3.24Å; R480-N548 WeakPolarHBondContact CD-OD1 3.31Å; R480-N548 PolarHBondContact NH1-OD1 2.82Å; S544-N548 PolarHBondContact O-N 2.77Å; S544-N548 PolarHBondContact O-ND2 3.1Å; M545-N548 WeakPolarHBondContact O-CB 3.39Å; M545-N548 PolarHBondContact O-N 3.45Å
549E95.3Very high96Very high141 Ų14149.3 Ų49.366%0.65927%0.267SS*.Hα-helixtrans-85.6-26.3178.8-67.5-177.3179.700114M545 L546 L547M545-E549 PolarHBondContact O-N 2.78Å; L546-E549 PolarHBondContact O-N 2.94Å; L547-E549 PolarHBondContact O-N 3.07Å
550T95.9Very high96Very high25 Ų2548.8 Ų48.815%0.15326%0.256CS..Hα-helixtrans-115-27.1-165.758.50000115.1L530 F531 L546 L547 P552L530-T550 HydrophobicContact CB-CG2 4.36Å; F531-T550 HydrophobicContact CB-CG2 4.05Å; L546-T550 WeakPolarHBondContact O-CB 3.38Å; L546-T550 WeakPolarHBondContact O-CG2 3.26Å; L546-T550 PolarHBondContact O-N 3.49Å; L546-T550 PolarHBondContact O-OG1 2.85Å; L547-T550 PolarHBondContact O-N 3.46Å; T550-P552 WeakPolarHBondContact O-CD 3.45Å
551V97.6Very high95.9Very high9 Ų951 Ų516%0.05526%0.261CS..SBendtrans-66.7122.9177.9177.70000108.6L475 W478 F522 L547 V555 I556L475-V551 HydrophobicContact CD1-CG1 4.41Å; L475-V551 HydrophobicContact CD1-CG2 4.47Å; W478-V551 HydrophobicContact CH2-CB 4.21Å; W478-V551 HydrophobicContact CH2-CG1 4.4Å; W478-V551 HydrophobicContact CH2-CG2 4.16Å; W478-V551 HydrophobicContact CZ3-CB 4.38Å; W478-V551 HydrophobicContact CZ3-CG1 4.18Å; W478-V551 HydrophobicContact CZ3-CG2 4.16Å; F522-V551 HydrophobicContact CE1-CB 4.46Å; F522-V551 HydrophobicContact CE1-CG1 4.48Å; F522-V551 HydrophobicContact CE1-CG2 3.85Å; F522-V551 HydrophobicContact CE2-CG2 4.33Å; F522-V551 HydrophobicContact CZ-CG2 3.75Å; L547-V551 HydrophobicContact CB-CG2 3.99Å; L547-V551 HydrophobicContact CD2-CG2 3.65Å; L547-V551 HydrophobicContact CG-CG2 4.44Å; L547-V551 VanDerWaalsContact O-CB 3.3Å; L547-V551 WeakPolarHBondContact O-CB 3.45Å; L547-V551 WeakPolarHBondContact O-CG2 3.46Å; L547-V551 PolarHBondContact O-N 3.01Å; V551-V555 HydrophobicContact CG1-CB 3.75Å; V551-V555 HydrophobicContact CG1-CG1 3.66Å; V551-I556 HydrophobicContact CG1-CG1 3.93Å
552P97.1Very high95.7Very high21 Ų2145.4 Ų45.414%0.13623%0.234CC..  trans-75.2156.1-177.631.4-35.5000111.8V15 T550 W554 V555 I556V15-P552 HydrophobicContact CB-CB 4.07Å; V15-P552 HydrophobicContact CB-CG 4.07Å; V15-P552 HydrophobicContact CG1-CB 4.5Å; V15-P552 HydrophobicContact CG1-CG 4.08Å; T550-P552 WeakPolarHBondContact O-CD 3.45Å; P552-W554 VanDerWaalsContact C-N 3.29Å; P552-W554 HydrophobicContact CG-CG 4.44Å; P552-W554 HydrophobicContact CG-CZ2 4.48Å; P552-W554 PolarHBondContact O-N 2.9Å; P552-V555 HydrophobicContact CG-CB 4.36Å; P552-V555 HydrophobicContact CG-CG2 3.8Å; P552-V555 WeakPolarHBondContact O-CB 3.26Å; P552-V555 PolarHBondContact O-N 2.91Å; P552-I556 PolarHBondContact O-N 3.22Å
553Q96.2Very high95.6Very high110 Ų11046 Ų4651%0.51424%0.235SC..Hα-helixtrans-55.1-41.5-175.2-170.960.145.800113.3V555 I556 D557Q553-V555 PolarHBondContact O-N 3.26Å; Q553-I556 WeakPolarHBondContact O-CA 3.37Å; Q553-I556 WeakPolarHBondContact O-CB 3.46Å; Q553-I556 PolarHBondContact O-N 3.06Å; Q553-D557 PolarHBondContact NE2-OD1 3.33Å; Q553-D557 PolarHBondContact O-N 3.21Å
554W96.5Very high95.1Very high17 Ų1747.1 Ų47.16%0.06424%0.241CC..Hα-helixtrans-60.2-22.3179.772.5-98.4000113.8V15 V17 L437 E439 C442 F443 L471 P552V15-W554 PolarHBondContact O-NE1 2.98Å; V17-W554 HydrophobicContact CG2-CH2 4.19Å; V17-W554 HydrophobicContact CG2-CZ2 3.99Å; L437-W554 HydrophobicContact CB-CH2 4.27Å; E439-W554 HydrophobicContact CB-CD2 4.04Å; E439-W554 HydrophobicContact CB-CG 4.02Å; E439-W554 HydrophobicContact CG-CB 3.97Å; E439-W554 HydrophobicContact CG-CD2 4.28Å; E439-W554 HydrophobicContact CG-CG 3.84Å; C442-W554 HydrophobicContact CB-CH2 4.27Å; C442-W554 HydrophobicContact CB-CZ3 3.89Å; F443-W554 HydrophobicContact CE1-CZ3 4.38Å; F443-W554 AromaticContact CE2-CE3 3.57Å; F443-W554 HydrophobicContact CE2-CE3 3.57Å; F443-W554 HydrophobicContact CE2-CZ3 4.03Å; F443-W554 AromaticContact CZ-CE3 3.46Å; F443-W554 HydrophobicContact CZ-CE3 3.46Å; F443-W554 VanDerWaalsContact CZ-CE3 3.46Å; F443-W554 AromaticContact CZ-CZ3 3.62Å; F443-W554 HydrophobicContact CZ-CZ3 3.62Å; L471-W554 HydrophobicContact CD1-CE3 4.38Å; L471-W554 HydrophobicContact CD1-CH2 4.35Å; L471-W554 HydrophobicContact CD1-CZ3 3.69Å; L471-W554 HydrophobicContact CD2-CH2 4.49Å; P552-W554 VanDerWaalsContact C-N 3.29Å; P552-W554 HydrophobicContact CG-CG 4.44Å; P552-W554 HydrophobicContact CG-CZ2 4.48Å; P552-W554 PolarHBondContact O-N 2.9Å
555V97.8Very high94.8Very high0 Ų047.4 Ų47.40%024%0.242CC..Hα-helixtrans-85.9-39.2172.4176.80000110.7V17 L471 L475 V551 P552 Q553 D557 I558 T559V17-V555 HydrophobicContact CG2-CG2 3.76Å; L471-V555 HydrophobicContact CD1-CG1 4.37Å; L471-V555 HydrophobicContact CD1-CG2 4.24Å; L471-V555 HydrophobicContact CD2-CG1 4.2Å; L471-V555 HydrophobicContact CD2-CG2 4.18Å; L475-V555 HydrophobicContact CD1-CG1 3.82Å; V551-V555 HydrophobicContact CG1-CB 3.75Å; V551-V555 HydrophobicContact CG1-CG1 3.66Å; P552-V555 HydrophobicContact CG-CB 4.36Å; P552-V555 HydrophobicContact CG-CG2 3.8Å; P552-V555 WeakPolarHBondContact O-CB 3.26Å; P552-V555 PolarHBondContact O-N 2.91Å; Q553-V555 PolarHBondContact O-N 3.26Å; V555-D557 VanDerWaalsContact C-N 3.31Å; V555-D557 PolarHBondContact O-N 3.48Å; V555-I558 PolarHBondContact O-N 3.28Å; V555-T559 HydrophobicContact CG1-CG2 3.94Å; V555-T559 WeakPolarHBondContact O-CB 3.41Å; V555-T559 WeakPolarHBondContact O-CG2 3.38Å; V555-T559 PolarHBondContact O-N 3.4Å; V555-T559 PolarHBondContact O-OG1 3.47Å
556I97Very high94.3Very high12 Ų1251.7 Ų51.76%0.06226%0.258CS..Hα-helixtrans-58.4-45.5176.4-63.8178.4000110.1V551 P552 Q553 I558 T559 V560 D561V551-I556 HydrophobicContact CG1-CG1 3.93Å; P552-I556 PolarHBondContact O-N 3.22Å; Q553-I556 WeakPolarHBondContact O-CA 3.37Å; Q553-I556 WeakPolarHBondContact O-CB 3.46Å; Q553-I556 PolarHBondContact O-N 3.06Å; I556-I558 PolarHBondContact O-N 2.98Å; I556-I558 VanDerWaalsContact O-N 3.08Å; I556-T559 PolarHBondContact O-N 3.12Å; I556-V560 HydrophobicContact CG2-CB 3.92Å; I556-V560 HydrophobicContact CG2-CG1 4.49Å; I556-V560 HydrophobicContact CG2-CG2 4.15Å; I556-V560 WeakPolarHBondContact O-CB 3.5Å; I556-V560 PolarHBondContact O-N 2.8Å; I556-D561 PolarHBondContact O-N 2.73Å
557D96.1Very high94Very high55 Ų5554.5 Ų54.529%0.29427%0.268SS..Hα-helixtrans-51.5-38.5-179.8-63-19000111.6Q553 V555 D561 K562 N563Q553-D557 PolarHBondContact NE2-OD1 3.33Å; Q553-D557 PolarHBondContact O-N 3.21Å; V555-D557 VanDerWaalsContact C-N 3.31Å; V555-D557 PolarHBondContact O-N 3.48Å; D557-D561 CarbonylContact O-C 3.57Å; D557-K562 PolarHBondContact O-N 3.31Å; D557-K562 VanDerWaalsContact O-N 3.17Å; D557-N563 WeakPolarHBondContact O-CB 3.25Å; D557-N563 PolarHBondContact O-N 3.08Å
558I95.8Very high93.6Very high5 Ų557.6 Ų57.63%0.02629%0.285CS..Hα-helixtrans-91.4-38.2-177.9-51-49.4000113.3F443 Q472 V555 I556 N563F443-I558 HydrophobicContact CD1-CG1 4.49Å; F443-I558 HydrophobicContact CE1-CD1 4.41Å; F443-I558 HydrophobicContact CE1-CG1 3.63Å; F443-I558 HydrophobicContact CE2-CG1 4.07Å; F443-I558 HydrophobicContact CZ-CB 4.48Å; F443-I558 HydrophobicContact CZ-CD1 4.2Å; F443-I558 HydrophobicContact CZ-CG1 3.36Å; Q472-I558 PolarHBondContact NE2-O 3.37Å; Q472-I558 VanDerWaalsContact NE2-O 3.11Å; V555-I558 PolarHBondContact O-N 3.28Å; I556-I558 PolarHBondContact O-N 2.98Å; I556-I558 VanDerWaalsContact O-N 3.08Å; I558-N563 WeakPolarHBondContact CD1-O 3.41Å
559T95.4Very high93.5Very high0 Ų061.3 Ų61.30%030%0.298CS..Hα-helixtrans-90.3-33.4-169.4570000113.2L471 Q472 L475 T481 V555 I556 K562L471-T559 HydrophobicContact CB-CG2 3.69Å; Q472-T559 HydrophobicContact CG-CG2 4.18Å; L475-T559 HydrophobicContact CD1-CG2 4.35Å; T481-T559 WeakPolarHBondContact CB-O 3.27Å; V555-T559 HydrophobicContact CG1-CG2 3.94Å; V555-T559 WeakPolarHBondContact O-CB 3.41Å; V555-T559 WeakPolarHBondContact O-CG2 3.38Å; V555-T559 PolarHBondContact O-N 3.4Å; V555-T559 PolarHBondContact O-OG1 3.47Å; I556-T559 PolarHBondContact O-N 3.12Å; T559-K562 WeakPolarHBondContact O-CE 3.19Å; T559-K562 PolarHBondContact O-NZ 2.74Å
560V94.3Very high93.3Very high30 Ų3055.3 Ų55.318%0.18227%0.27CS..THydrogen-bonded Turntrans-102.6-58179.3178.80000109.4W478 R480 T481 I556 K562W478-V560 HydrophobicContact CH2-CG2 4.39Å; W478-V560 HydrophobicContact CZ3-CG2 3.98Å; R480-V560 HydrophobicContact CG-CG1 4.13Å; R480-V560 HydrophobicContact CG-CG2 4.07Å; T481-V560 HydrophobicContact CG2-CG2 4.18Å; I556-V560 HydrophobicContact CG2-CB 3.92Å; I556-V560 HydrophobicContact CG2-CG1 4.49Å; I556-V560 HydrophobicContact CG2-CG2 4.15Å; I556-V560 WeakPolarHBondContact O-CB 3.5Å; I556-V560 PolarHBondContact O-N 2.8Å; V560-K562 VanDerWaalsContact C-N 3.25Å; V560-K562 PolarHBondContact O-N 3.43Å
561D93.5Very high93.3Very high73 Ų7355.9 Ų55.939%0.3927%0.274SS..SBendtrans-79.9-9.7-171.8-52.6-23.3000112.9I556 D557 N563I556-D561 PolarHBondContact O-N 2.73Å; D557-D561 CarbonylContact O-C 3.57Å; D561-N563 WeakPolarHBondContact CB-ND2 3.45Å; D561-N563 PolarHBondContact O-N 3Å
562K90.8Very high93.2Very high61 Ų6155.8 Ų55.827%0.26527%0.273SS..  trans53.125.7-178.8-49.1-57-174.9-173.80114T481 I483 D557 T559 V560 M564T481-K562 PolarHBondContact O-NZ 3.48Å; I483-K562 HydrophobicContact CD1-CG 4.17Å; D557-K562 PolarHBondContact O-N 3.31Å; D557-K562 VanDerWaalsContact O-N 3.17Å; T559-K562 WeakPolarHBondContact O-CE 3.19Å; T559-K562 PolarHBondContact O-NZ 2.74Å; V560-K562 VanDerWaalsContact C-N 3.25Å; V560-K562 PolarHBondContact O-N 3.43Å; K562-M564 PolarHBondContact O-N 2.87Å
563N91.8Very high93.1Very high99 Ų9957.2 Ų57.253%0.52928%0.276SS..  trans-75.585.7177.9-71.8-37000110.4D557 I558 D561D557-N563 WeakPolarHBondContact O-CB 3.25Å; D557-N563 PolarHBondContact O-N 3.08Å; I558-N563 WeakPolarHBondContact CD1-O 3.41Å; D561-N563 WeakPolarHBondContact CB-ND2 3.45Å; D561-N563 PolarHBondContact O-N 3Å
564M84.1Confident92.9Very high88 Ų8852.1 Ų52.143%0.43325%0.252SS..PPolyproline II helixtrans-58.2141-179-71.8-64.5-81.900112W446 N465 K562W446-M564 HydrophobicContact CH2-CB 4.46Å; W446-M564 HydrophobicContact CH2-CE 3.79Å; W446-M564 HydrophobicContact CZ3-CE 4.1Å; N465-M564 HydrophobicContact CB-CE 3.99Å; K562-M564 PolarHBondContact O-N 2.87Å
565P89.1Confident92.6Very high29 Ų2953.7 Ų53.719%0.18826%0.26CS..PPolyproline II helixtrans-65.2164.2-177.320.5-23.4000111.5F443 W446 N465F443-P565 HydrophobicContact CB-CB 3.92Å; F443-P565 HydrophobicContact CB-CG 3.79Å; F443-P565 HydrophobicContact CD1-CG 4.21Å; F443-P565 HydrophobicContact CG-CB 4.27Å; F443-P565 HydrophobicContact CG-CG 4.02Å; W446-P565 HydrophobicContact CZ2-CB 4.31Å; W446-P565 HydrophobicContact CZ2-CG 3.69Å; W446-P565 WeakPolarHBondContact CZ2-O 3.28Å; N465-P565 HydrophobicContact CB-CG 4.31Å
566K86.8Confident92.1Very high191 Ų19154.9 Ų54.983%0.8327%0.268SS*.PPolyproline II helixtrans-76.1149.2177.1-67.6-177.1-179.9177.50111.1W446W446-K566 PolarHBondContact NE1-O 3.16Å
567F89.5Confident91.6Very high107 Ų10755.2 Ų55.247%0.46927%0.269SS..PPolyproline II helixtrans-66.1143171.8-67.2-68.2000112W446 K463 M595W446-F567 AromaticContact CD2-CD1 3.76Å; W446-F567 HydrophobicContact CD2-CD1 3.76Å; W446-F567 AromaticContact CD2-CE1 3.7Å; W446-F567 HydrophobicContact CD2-CE1 3.7Å; W446-F567 AromaticContact CE2-CD1 3.97Å; W446-F567 HydrophobicContact CE3-CD1 4Å; W446-F567 AromaticContact CE3-CE1 3.43Å; W446-F567 HydrophobicContact CE3-CE1 3.43Å; W446-F567 VanDerWaalsContact CE3-CE1 3.43Å; W446-F567 HydrophobicContact CE3-CZ 4.33Å; W446-F567 HydrophobicContact CG-CD1 4.1Å; W446-F567 HydrophobicContact CG-CE1 4.39Å; W446-F567 HydrophobicContact CH2-CE1 4.01Å; W446-F567 HydrophobicContact CH2-CZ 4.32Å; W446-F567 HydrophobicContact CZ2-CD1 4.38Å; W446-F567 HydrophobicContact CZ2-CE1 4.29Å; W446-F567 HydrophobicContact CZ3-CD1 4.37Å; W446-F567 AromaticContact CZ3-CE1 3.58Å; W446-F567 HydrophobicContact CZ3-CE1 3.58Å; W446-F567 HydrophobicContact CZ3-CZ 4.05Å; K463-F567 HydrophobicContact CB-CE1 3.73Å; K463-F567 HydrophobicContact CB-CZ 4.12Å; K463-F567 HydrophobicContact CG-CE1 4.29Å; F567-M595 HydrophobicContact CD1-CE 3.76Å; F567-M595 HydrophobicContact CE1-CE 3.87Å
568N89.7Confident90.7Very high66 Ų6658.1 Ų58.135%0.35329%0.294SS..PPolyproline II helixtrans-78.7140.2171.9-65.7-34.9000110.1A444 S593 D594A444-N568 PolarHBondContact O-ND2 3.5Å; A444-N568 VanDerWaalsContact O-ND2 3.08Å; N568-S593 WeakPolarHBondContact O-CA 3.19Å; N568-D594 HydrophobicContact CB-CB 4.36Å; N568-D594 PolarHBondContact O-N 3.18Å
569K93.2Very high89.8Confident149 Ų14961.2 Ų61.265%0.64832%0.316SS*.EExtended strand (participates in β ladder)trans-117.7144.1176.3-65.6-170.6179.7-173.80111.4A592K569-A592 CarbonylContact C-O 3.54Å; K569-A592 WeakPolarHBondContact CA-O 3.17Å; K569-A592 WeakPolarHBondContact CB-O 3.34Å
570I92.4Very high88.4Confident14 Ų1463.3 Ų63.37%0.07233%0.331CS..EExtended strand (participates in β ladder)trans-108.1122.1172.9-67179.9000108.5S591 A592 D594 L659 R660 K663 L673I570-S591 WeakPolarHBondContact O-CA 3.34Å; I570-A592 PolarHBondContact N-O 2.89Å; I570-A592 PolarHBondContact O-N 2.85Å; I570-D594 HydrophobicContact CD1-CB 3.72Å; I570-D594 HydrophobicContact CG1-CB 3.8Å; I570-L659 HydrophobicContact CD1-CB 4.37Å; I570-R660 HydrophobicContact CD1-CB 3.72Å; I570-K663 HydrophobicContact CD1-CD 4.27Å; I570-K663 HydrophobicContact CG2-CD 4.11Å; I570-L673 HydrophobicContact CG2-CB 4.5Å
571P95Very high86.8Confident38 Ų3865.4 Ų65.425%0.24736%0.358CS..EExtended strand (participates in β ladder)trans-74.3136.7163.631.1-32.5000109.8L590P571-L590 WeakPolarHBondContact CA-O 3.39Å
572F96Very high85.2Confident6 Ų664.2 Ų64.23%0.02636%0.359CS..EExtended strand (participates in β ladder)trans-147158.9177.568.5-84.5000111.7L574 L590 A592 V601 L659 L673 L675F572-L574 HydrophobicContact CE2-CB 4.44Å; F572-L590 HydrophobicContact CD1-CB 4.35Å; F572-L590 HydrophobicContact CD2-CB 4.41Å; F572-L590 HydrophobicContact CE1-CB 3.84Å; F572-L590 HydrophobicContact CE2-CB 3.91Å; F572-L590 HydrophobicContact CE2-CD1 3.93Å; F572-L590 HydrophobicContact CE2-CG 4.48Å; F572-L590 HydrophobicContact CZ-CB 3.6Å; F572-L590 HydrophobicContact CZ-CD1 3.97Å; F572-L590 HydrophobicContact CZ-CG 4.43Å; F572-L590 PolarHBondContact N-O 3.46Å; F572-L590 PolarHBondContact O-N 3.34Å; F572-L590 VanDerWaalsContact O-O 3.13Å; F572-A592 HydrophobicContact CE1-CB 3.91Å; F572-V601 HydrophobicContact CE2-CG1 4.33Å; F572-V601 HydrophobicContact CZ-CG2 4.39Å; F572-L659 HydrophobicContact CD1-CD1 3.96Å; F572-L659 HydrophobicContact CE1-CD1 3.79Å; F572-L659 HydrophobicContact CZ-CD1 4.4Å; F572-L673 CarbonylContact C-O 3.47Å; F572-L673 WeakPolarHBondContact CA-O 3.43Å; F572-L673 HydrophobicContact CB-CB 3.83Å; F572-L673 HydrophobicContact CB-CD2 4.15Å; F572-L673 HydrophobicContact CB-CG 4.08Å; F572-L673 VanDerWaalsContact CB-O 3.25Å; F572-L673 WeakPolarHBondContact CB-O 3.26Å; F572-L675 HydrophobicContact CD2-CD1 3.87Å; F572-L675 HydrophobicContact CD2-CG 4.35Å; F572-L675 HydrophobicContact CE2-CD1 4.11Å
573Y93.9Very high83.3Confident51 Ų5170.5 Ų70.520%0.239%0.386CS..EExtended strand (participates in β ladder)trans-102.5141.9172.7-69-68.8000110.4K587 D588 R589 D672 L673 L675Y573-K587 HydrophobicContact CD1-CD 3.78Å; Y573-K587 HydrophobicContact CD1-CG 3.42Å; Y573-K587 VanDerWaalsContact CD1-CG 3.42Å; Y573-K587 VanDerWaalsContact CD2-CE 3.42Å; Y573-K587 HydrophobicContact CE1-CD 3.83Å; Y573-K587 VanDerWaalsContact CE1-CE 3.41Å; Y573-K587 HydrophobicContact CE1-CG 3.79Å; Y573-K587 HydrophobicContact CG-CD 4.22Å; Y573-K587 HydrophobicContact CG-CG 4.11Å; Y573-D588 WeakPolarHBondContact CA-O 3.36Å; Y573-R589 HydrophobicContact CD1-CB 3.87Å; Y573-R589 HydrophobicContact CD1-CG 4.03Å; Y573-R589 HydrophobicContact CE1-CB 3.58Å; Y573-R589 HydrophobicContact CE1-CG 3.63Å; Y573-D672 HydrophobicContact CD2-CB 4.04Å; Y573-D672 HydrophobicContact CE2-CB 3.88Å; Y573-L673 PolarHBondContact N-O 3.12Å; Y573-L675 PolarHBondContact O-N 3.21Å
574L92.3Very high81.6Confident3 Ų372.7 Ų72.72%0.01640%0.403CS..EExtended strand (participates in β ladder)trans-121.4123.9175.7-17162.4000109.2F572 D588 L590 V601 V605 I609 L646 L675 Y677F572-L574 HydrophobicContact CE2-CB 4.44Å; L574-D588 PolarHBondContact N-O 3.45Å; L574-L590 HydrophobicContact CB-CD1 4.13Å; L574-L590 HydrophobicContact CD2-CD1 3.84Å; L574-V601 HydrophobicContact CD1-CG1 4.06Å; L574-V601 HydrophobicContact CD2-CG1 4.35Å; L574-V605 HydrophobicContact CD1-CG2 4.23Å; L574-V605 HydrophobicContact CD2-CG2 3.83Å; L574-V605 HydrophobicContact CG-CG2 4.42Å; L574-I609 HydrophobicContact CD2-CD1 3.97Å; L574-L646 HydrophobicContact CD1-CD1 3.95Å; L574-L675 WeakPolarHBondContact CA-O 3.35Å; L574-L675 HydrophobicContact CD1-CB 4.01Å; L574-Y677 HydrophobicContact CD1-CD1 3.77Å; L574-Y677 HydrophobicContact CD1-CE1 4.48Å; L574-Y677 HydrophobicContact CD2-CD1 4.5Å; L574-Y677 HydrophobicContact CG-CD1 3.75Å; L574-Y677 HydrophobicContact CG-CE1 3.98Å
575Q89.7Confident80.2Confident51 Ų5174 Ų7424%0.23841%0.411CS..EExtended strand (participates in β ladder)trans-139.9150.2-172-58.8-171.3-43.900111.8K587 L675 H676 Y677Q575-K587 HydrophobicContact CG-CG 4.45Å; Q575-K587 VanDerWaalsContact NE2-CD 3.28Å; Q575-K587 VanDerWaalsContact NE2-CG 3.28Å; Q575-L675 PolarHBondContact N-O 3.1Å; Q575-H676 CarbonylContact O-C 3.51Å; Q575-H676 WeakPolarHBondContact O-CA 3.4Å; Q575-Y677 WeakPolarHBondContact O-CD1 3.33Å; Q575-Y677 WeakPolarHBondContact O-CE1 3.32Å; Q575-Y677 PolarHBondContact O-N 3.13Å
576P88.1Confident78.8Confident25 Ų2581 Ų8116%0.16244%0.439CS..EExtended strand (participates in β ladder)trans-65.6139170.326.4-31.9000110.3S580 A582 Y677P576-S580 WeakPolarHBondContact CB-OG 3.16Å; P576-A582 HydrophobicContact CB-CB 4.05Å; P576-A582 HydrophobicContact CG-CB 4.46Å; P576-Y677 HydrophobicContact CB-CE2 4.14Å
577H86.5Confident77.9Confident19 Ų1977.1 Ų77.19%0.08842%0.422CS..  trans-66.8148.2171.3-170-98.7000110.2S579 S580 D650 H676 Y677 R678H577-S579 WeakPolarHBondContact ND1-CB 3.26Å; H577-S579 PolarHBondContact ND1-N 2.76Å; H577-S579 PolarHBondContact ND1-OG 2.83Å; H577-S579 PolarHBondContact O-N 3.06Å; H577-S580 WeakPolarHBondContact O-CB 3.17Å; H577-S580 PolarHBondContact O-N 2.93Å; H577-S580 PolarHBondContact O-OG 3.5Å; H577-D650 IonicContact NE2-OD1 2.92Å; H577-H676 HydrophobicContact CB-CB 4.15Å; H577-Y677 PolarHBondContact N-O 2.64Å; H577-R678 HydrophobicContact CB-CB 4.04Å
578S77.9Confident77.4Confident116 Ų11675.4 Ų75.481%0.81142%0.418SS*.G310 helixtrans-55.7-27.1-179.155.90000113.6
579S75.4Confident77.5Confident70 Ų7079.6 Ų79.649%0.4943%0.428SS..G310 helixtrans-83.2-3.9177.6750000115.1H577 G581 R678H577-S579 WeakPolarHBondContact ND1-CB 3.26Å; H577-S579 PolarHBondContact ND1-N 2.76Å; H577-S579 PolarHBondContact ND1-OG 2.83Å; H577-S579 PolarHBondContact O-N 3.06Å; S579-G581 VanDerWaalsContact C-N 3.3Å; S579-G581 PolarHBondContact O-N 3.47Å; S579-R678 WeakPolarHBondContact OG-CD 3.34Å; S579-R678 PolarHBondContact OG-NH1 3.28Å
580S67Low77.5Confident44 Ų4474.9 Ų74.931%0.30841%0.41SS..G310 helixtrans-81.3-7.7-175.575.50000113.9P576 H577 A582P576-S580 WeakPolarHBondContact CB-OG 3.16Å; H577-S580 WeakPolarHBondContact O-CB 3.17Å; H577-S580 PolarHBondContact O-N 2.93Å; H577-S580 PolarHBondContact O-OG 3.5Å; S580-A582 PolarHBondContact O-N 2.74Å; S580-A582 VanDerWaalsContact O-N 3.08Å
581G59.7Low77.5Confident74 Ų7477.5 Ų77.576%0.76343%0.43SS*.  trans70.1-2.9-178.800000115S579 K583S579-G581 VanDerWaalsContact C-N 3.3Å; S579-G581 PolarHBondContact O-N 3.47Å; G581-K583 PolarHBondContact O-N 2.98Å
582A60.8Low77.5Confident48 Ų4876.5 Ų76.540%0.39743%0.425SS..  trans-73.3122.9179.400000111.2P576 S580 T584P576-A582 HydrophobicContact CB-CB 4.05Å; P576-A582 HydrophobicContact CG-CB 4.46Å; S580-A582 PolarHBondContact O-N 2.74Å; S580-A582 VanDerWaalsContact O-N 3.08Å; A582-T584 PolarHBondContact O-N 3.1Å
583K51.3Low77.3Confident193 Ų19377.9 Ų77.984%0.83944%0.435SS*.  trans-65.1127.1172.6-72-178.4179.71760108.8G581 L585G581-K583 PolarHBondContact O-N 2.98Å; K583-L585 PolarHBondContact O-N 3.42Å
584T54.3Low77.2Confident144 Ų14475.8 Ų75.888%0.88343%0.428SS*.  trans-24.992.3-178.214.50000114.3A582A582-T584 PolarHBondContact O-N 3.1Å
585L55.4Low77.2Confident116 Ų11676.5 Ų76.561%0.60743%0.431SS*.  trans-78.4154.7163.6-94.9141000109.3K583 K587K583-L585 PolarHBondContact O-N 3.42Å; L585-K587 PolarHBondContact O-N 3.28Å
586K59.5Low77.4Confident177 Ų17776.5 Ų76.577%0.7743%0.432SS*.  trans-47.8135.7-175.3-146.2173.7-177.4-179.70110.4D588K586-D588 PolarHBondContact O-N 2.95Å
587K67.3Low77.6Confident108 Ų10879 Ų7947%0.4744%0.442SS..  trans-67.199.7174.7179.6171.7-168.7176.50108.6Y573 Q575 L585 R589Y573-K587 HydrophobicContact CD1-CD 3.78Å; Y573-K587 HydrophobicContact CD1-CG 3.42Å; Y573-K587 VanDerWaalsContact CD1-CG 3.42Å; Y573-K587 VanDerWaalsContact CD2-CE 3.42Å; Y573-K587 HydrophobicContact CE1-CD 3.83Å; Y573-K587 VanDerWaalsContact CE1-CE 3.41Å; Y573-K587 HydrophobicContact CE1-CG 3.79Å; Y573-K587 HydrophobicContact CG-CD 4.22Å; Y573-K587 HydrophobicContact CG-CG 4.11Å; Q575-K587 HydrophobicContact CG-CG 4.45Å; Q575-K587 VanDerWaalsContact NE2-CD 3.28Å; Q575-K587 VanDerWaalsContact NE2-CG 3.28Å; L585-K587 PolarHBondContact O-N 3.28Å; K587-R589 PolarHBondContact O-N 3.28Å
588D79.9Confident78Confident72 Ų7278.1 Ų78.139%0.38544%0.438SS..EExtended strand (participates in β ladder)trans-79.3116.9-179.9-70.4-26.3000109.7Y573 L574 K586Y573-D588 WeakPolarHBondContact CA-O 3.36Å; L574-D588 PolarHBondContact N-O 3.45Å; K586-D588 PolarHBondContact O-N 2.95Å
589R91.2Very high78.8Confident153 Ų15376 Ų7658%0.57741%0.412SS*.EExtended strand (participates in β ladder)trans-92109.1172.5-165.5178.2-174.3-166.8-0.6108.2Y573 K587 D672Y573-R589 HydrophobicContact CD1-CB 3.87Å; Y573-R589 HydrophobicContact CD1-CG 4.03Å; Y573-R589 HydrophobicContact CE1-CB 3.58Å; Y573-R589 HydrophobicContact CE1-CG 3.63Å; K587-R589 PolarHBondContact O-N 3.28Å; R589-D672 IonicContact CZ-OD2 2.96Å; R589-D672 VanDerWaalsContact CZ-OD2 3.29Å; R589-D672 IonicContact NE-OD2 3.28Å; R589-D672 PolarHBondContact NE-OD2 3.45Å; R589-D672 VanDerWaalsContact NE-OD2 3.09Å; R589-D672 IonicContact NH2-OD2 3.46Å; R589-D672 PolarHBondContact NH2-OD2 3.23Å
590L93.8Very high79.6Confident50 Ų5076.3 Ų76.326%0.26240%0.404SS..EExtended strand (participates in β ladder)trans-106.3163.2179.9-60.3177.4000110.5P571 F572 L574P571-L590 WeakPolarHBondContact CA-O 3.39Å; F572-L590 HydrophobicContact CD1-CB 4.35Å; F572-L590 HydrophobicContact CD2-CB 4.41Å; F572-L590 HydrophobicContact CE1-CB 3.84Å; F572-L590 HydrophobicContact CE2-CB 3.91Å; F572-L590 HydrophobicContact CE2-CD1 3.93Å; F572-L590 HydrophobicContact CE2-CG 4.48Å; F572-L590 HydrophobicContact CZ-CB 3.6Å; F572-L590 HydrophobicContact CZ-CD1 3.97Å; F572-L590 HydrophobicContact CZ-CG 4.43Å; F572-L590 PolarHBondContact N-O 3.46Å; F572-L590 PolarHBondContact O-N 3.34Å; F572-L590 VanDerWaalsContact O-O 3.13Å; L574-L590 HydrophobicContact CB-CD1 4.13Å; L574-L590 HydrophobicContact CD2-CD1 3.84Å
591S93.3Very high80.9Confident70 Ų7074.3 Ų74.349%0.4939%0.391SS..EExtended strand (participates in β ladder)trans-142.7128171.2-175.30000110.1I570I570-S591 WeakPolarHBondContact O-CA 3.34Å
592A93.8Very high82.4Confident17 Ų1771.1 Ų71.114%0.1436%0.356CS..EExtended strand (participates in β ladder)trans-135.1172.5-179.900000110.9K569 I570 F572 L596 L659K569-A592 CarbonylContact C-O 3.54Å; K569-A592 WeakPolarHBondContact CA-O 3.17Å; K569-A592 WeakPolarHBondContact CB-O 3.34Å; I570-A592 PolarHBondContact N-O 2.89Å; I570-A592 PolarHBondContact O-N 2.85Å; F572-A592 HydrophobicContact CE1-CB 3.91Å; A592-L596 HydrophobicContact CB-CB 4.16Å; A592-L596 HydrophobicContact CB-CD2 3.51Å; A592-L596 HydrophobicContact CB-CG 4.38Å; A592-L659 HydrophobicContact CB-CD1 4.15Å
593S92.6Very high83.9Confident35 Ų3569.6 Ų69.625%0.24534%0.341CS..EExtended strand (participates in β ladder)trans-53.7143.1168.6174.20000110.5N568 M595 L596N568-S593 WeakPolarHBondContact O-CA 3.19Å; S593-M595 PolarHBondContact O-N 2.82Å; S593-M595 PolarHBondContact OG-N 2.83Å; S593-L596 VanDerWaalsContact O-CB 3.3Å; S593-L596 WeakPolarHBondContact O-CB 3.39Å; S593-L596 PolarHBondContact O-N 2.83Å; S593-L596 VanDerWaalsContact O-N 3.09Å
594D91.8Very high85.7Confident7 Ų763.8 Ų63.84%0.03732%0.316CS..THydrogen-bonded Turntrans-60.4-27.3173.570.8-41.3000113.3N568 I570 R660N568-D594 HydrophobicContact CB-CB 4.36Å; N568-D594 PolarHBondContact O-N 3.18Å; I570-D594 HydrophobicContact CD1-CB 3.72Å; I570-D594 HydrophobicContact CG1-CB 3.8Å; D594-R660 HydrophobicContact CB-CB 4.25Å; D594-R660 WeakPolarHBondContact O-CG 3.47Å; D594-R660 PolarHBondContact O-N 3.34Å; D594-R660 VanDerWaalsContact O-N 3.14Å; D594-R660 WeakPolarHBondContact OD2-CD 3.44Å; D594-R660 IonicContact OD2-NH1 3.55Å; D594-R660 PolarHBondContact OD2-NH1 2.88Å
595M92Very high87.3Confident18 Ų1857 Ų579%0.08927%0.274CS..THydrogen-bonded Turntrans-86.22.5175.8-60.7178.5-71.700114.1W446 K463 F567 S593 Q597W446-M595 HydrophobicContact CB-CE 3.52Å; W446-M595 HydrophobicContact CB-CG 4.4Å; W446-M595 HydrophobicContact CB-SD 3.43Å; W446-M595 WeakPolarHBondContact CB-SD 3.45Å; W446-M595 HydrophobicContact CG-CE 4.26Å; W446-M595 VanDerWaalsContact O-SD 3.38Å; K463-M595 HydrophobicContact CB-CE 3.97Å; K463-M595 HydrophobicContact CD-CE 4.1Å; K463-M595 HydrophobicContact CD-SD 4.08Å; K463-M595 HydrophobicContact CG-CE 3.83Å; K463-M595 HydrophobicContact CG-SD 4.42Å; F567-M595 HydrophobicContact CD1-CE 3.76Å; F567-M595 HydrophobicContact CE1-CE 3.87Å; S593-M595 PolarHBondContact O-N 2.82Å; S593-M595 PolarHBondContact OG-N 2.83Å; M595-Q597 PolarHBondContact O-N 2.91Å
596L93.7Very high88.8Confident51 Ų5152.3 Ų52.327%0.26725%0.249SC..  trans-62.7128179.7-171.373.9000109.4A592 S593 K600 V601 D658 L659A592-L596 HydrophobicContact CB-CB 4.16Å; A592-L596 HydrophobicContact CB-CD2 3.51Å; A592-L596 HydrophobicContact CB-CG 4.38Å; S593-L596 VanDerWaalsContact O-CB 3.3Å; S593-L596 WeakPolarHBondContact O-CB 3.39Å; S593-L596 PolarHBondContact O-N 2.83Å; S593-L596 VanDerWaalsContact O-N 3.09Å; L596-K600 HydrophobicContact CD1-CB 3.67Å; L596-K600 HydrophobicContact CD1-CG 4.06Å; L596-K600 HydrophobicContact CD2-CB 4.37Å; L596-K600 HydrophobicContact CG-CB 4.02Å; L596-V601 HydrophobicContact CD2-CG2 3.85Å; L596-D658 CarbonylContact O-C 3.56Å; L596-D658 VanDerWaalsContact O-CA 3.32Å; L596-D658 WeakPolarHBondContact O-CA 3.33Å; L596-L659 HydrophobicContact CB-CD1 4.06Å; L596-L659 HydrophobicContact CB-CG 4.26Å; L596-L659 HydrophobicContact CD2-CD1 4.27Å; L596-L659 WeakPolarHBondContact O-CG 3.41Å; L596-L659 PolarHBondContact O-N 3.33Å
597Q93.4Very high90Very high78 Ų7847.9 Ų47.936%0.36423%0.231SC..BIsolated β-bridgetrans-71.9148176-73.3178.3-20.600111.4M595 R599 K600 M657M595-Q597 PolarHBondContact O-N 2.91Å; Q597-R599 PolarHBondContact O-N 3.14Å; Q597-K600 PolarHBondContact O-N 2.91Å; Q597-K600 VanDerWaalsContact O-N 3.09Å; Q597-M657 CarbonylContact C-O 3.6Å; Q597-M657 WeakPolarHBondContact CA-O 3.29Å
598V94.4Very high90.7Very high0 Ų048.6 Ų48.60%023%0.234CC..Hα-helixtrans-54.3-39.7175.11640000111.1K600 V601 M602 L646 L653 D654 P655 M657 V662V598-K600 VanDerWaalsContact C-N 3.29Å; V598-K600 PolarHBondContact O-N 3.22Å; V598-V601 WeakPolarHBondContact O-CA 3.43Å; V598-V601 WeakPolarHBondContact O-CB 3.43Å; V598-V601 PolarHBondContact O-N 3.37Å; V598-M602 HydrophobicContact CG1-CG 4.35Å; V598-M602 HydrophobicContact CG1-SD 3.96Å; V598-M602 WeakPolarHBondContact O-CG 3.36Å; V598-M602 PolarHBondContact O-N 3.49Å; V598-L646 HydrophobicContact CG1-CB 4.1Å; V598-L646 HydrophobicContact CG1-CD2 3.81Å; V598-L653 HydrophobicContact CG1-CB 3.87Å; V598-L653 HydrophobicContact CG1-CD1 4.43Å; V598-L653 HydrophobicContact CG2-CB 4.19Å; V598-L653 HydrophobicContact CG2-CD1 4.08Å; V598-D654 WeakPolarHBondContact CB-O 3.44Å; V598-P655 PolarHBondContact N-O 3.1Å; V598-M657 HydrophobicContact CG2-CB 4.28Å; V598-M657 WeakPolarHBondContact CG2-O 3.32Å; V598-M657 PolarHBondContact N-O 3.33Å; V598-V662 HydrophobicContact CG2-CG2 3.85Å
599R93.5Very high90.4Very high72 Ų7246.8 Ų46.827%0.27222%0.224SC..Hα-helixtrans-52.1-43.6175.5-176.7-178.6-77169.11.1113.2Q597 V601 M602 E603 E641 P655Q597-R599 PolarHBondContact O-N 3.14Å; R599-V601 PolarHBondContact O-N 3.39Å; R599-M602 WeakPolarHBondContact O-CA 3.18Å; R599-M602 WeakPolarHBondContact O-CB 3.48Å; R599-M602 PolarHBondContact O-N 3.26Å; R599-E603 PolarHBondContact O-N 3.13Å; R599-E641 IonicContact CZ-OE2 3.76Å; R599-E641 IonicContact NE-OE2 3.03Å; R599-E641 PolarHBondContact NE-OE2 3.44Å; R599-E641 IonicContact NH2-OE1 3.74Å; R599-E641 IonicContact NH2-OE2 2.77Å; R599-E641 PolarHBondContact NH2-OE2 3.18Å; R599-P655 HydrophobicContact CB-CB 3.99Å; R599-P655 PolarHBondContact N-O 3.42Å
600K93.3Very high89.5Confident75 Ų7541.1 Ų41.133%0.32621%0.205SC..Hα-helixtrans-66.2-26.8178.5-70.3-56.4-171.4-179.80112.8L596 Q597 V598 E603 H604 E633L596-K600 HydrophobicContact CD1-CB 3.67Å; L596-K600 HydrophobicContact CD1-CG 4.06Å; L596-K600 HydrophobicContact CD2-CB 4.37Å; L596-K600 HydrophobicContact CG-CB 4.02Å; Q597-K600 PolarHBondContact O-N 2.91Å; Q597-K600 VanDerWaalsContact O-N 3.09Å; V598-K600 VanDerWaalsContact C-N 3.29Å; V598-K600 PolarHBondContact O-N 3.22Å; K600-E603 WeakPolarHBondContact CD-OE2 3.3Å; K600-E603 WeakPolarHBondContact CE-OE2 3.39Å; K600-E603 IonicContact NZ-OE1 3.9Å; K600-E603 IonicContact NZ-OE2 2.8Å; K600-E603 PolarHBondContact NZ-OE2 2.86Å; K600-H604 PolarHBondContact O-N 2.84Å; K600-E633 IonicContact NZ-OE1 3.47Å; K600-E633 PolarHBondContact NZ-OE1 2.75Å; K600-E633 VanDerWaalsContact NZ-OE1 3.14Å
601V93.2Very high88.2Confident3 Ų340.9 Ų40.92%0.01820%0.203CC..Hα-helixtrans-75.2-35.5171-174.80000111F572 L574 L596 V598 R599 H604 V605 L646 L659 L675F572-V601 HydrophobicContact CE2-CG1 4.33Å; F572-V601 HydrophobicContact CZ-CG2 4.39Å; L574-V601 HydrophobicContact CD1-CG1 4.06Å; L574-V601 HydrophobicContact CD2-CG1 4.35Å; L596-V601 HydrophobicContact CD2-CG2 3.85Å; V598-V601 WeakPolarHBondContact O-CA 3.43Å; V598-V601 WeakPolarHBondContact O-CB 3.43Å; V598-V601 PolarHBondContact O-N 3.37Å; R599-V601 PolarHBondContact O-N 3.39Å; V601-H604 WeakPolarHBondContact O-CB 3.49Å; V601-H604 PolarHBondContact O-N 2.88Å; V601-V605 WeakPolarHBondContact O-CG2 3.48Å; V601-V605 PolarHBondContact O-N 2.89Å; V601-L646 HydrophobicContact CB-CD2 3.81Å; V601-L646 HydrophobicContact CG1-CD1 4.24Å; V601-L646 HydrophobicContact CG1-CD2 3.73Å; V601-L659 HydrophobicContact CG2-CD2 4.19Å; V601-L675 HydrophobicContact CG1-CD1 4.35Å
602M91.6Very high86.3Confident6 Ų642.8 Ų42.83%0.0321%0.208CC..Hα-helixtrans-64.8-44174.5-60.616472.600111.6V598 R599 H604 V605 Y606 E641 I644 L646 P655V598-M602 HydrophobicContact CG1-CG 4.35Å; V598-M602 HydrophobicContact CG1-SD 3.96Å; V598-M602 WeakPolarHBondContact O-CG 3.36Å; V598-M602 PolarHBondContact O-N 3.49Å; R599-M602 WeakPolarHBondContact O-CA 3.18Å; R599-M602 WeakPolarHBondContact O-CB 3.48Å; R599-M602 PolarHBondContact O-N 3.26Å; M602-H604 VanDerWaalsContact C-N 3.3Å; M602-H604 PolarHBondContact O-N 3.47Å; M602-V605 PolarHBondContact O-N 3.02Å; M602-Y606 WeakPolarHBondContact O-CB 3.37Å; M602-Y606 PolarHBondContact O-N 3.35Å; M602-E641 HydrophobicContact CE-CB 4.38Å; M602-E641 HydrophobicContact CE-CG 4.25Å; M602-I644 HydrophobicContact CB-CB 4.31Å; M602-I644 HydrophobicContact CB-CG2 4.28Å; M602-I644 HydrophobicContact CE-CB 4.38Å; M602-I644 WeakPolarHBondContact CE-O 3.23Å; M602-I644 HydrophobicContact CG-CG2 4.37Å; M602-L646 HydrophobicContact CG-CB 4Å; M602-P655 HydrophobicContact CE-CG 4.43Å; M602-P655 HydrophobicContact SD-CB 4.12Å; M602-P655 HydrophobicContact SD-CG 4.05Å
603E91.8Very high84Confident17 Ų1748 Ų488%0.07923%0.233CC..Hα-helixtrans-55.5-46.3171.9-72168.9-15000110.9R599 K600 V605 Y606 E607 A637 A640R599-E603 PolarHBondContact O-N 3.13Å; K600-E603 WeakPolarHBondContact CD-OE2 3.3Å; K600-E603 WeakPolarHBondContact CE-OE2 3.39Å; K600-E603 IonicContact NZ-OE1 3.9Å; K600-E603 IonicContact NZ-OE2 2.8Å; K600-E603 PolarHBondContact NZ-OE2 2.86Å; E603-V605 PolarHBondContact O-N 2.83Å; E603-Y606 PolarHBondContact O-N 2.75Å; E603-E607 WeakPolarHBondContact O-CB 3.39Å; E603-E607 WeakPolarHBondContact O-CG 3.37Å; E603-E607 PolarHBondContact O-N 3.3Å; E603-A637 WeakPolarHBondContact OE1-CB 3.28Å; E603-A640 HydrophobicContact CB-CB 4.46Å; E603-A640 HydrophobicContact CG-CB 3.96Å
604H90.3Very high81.7Confident71 Ų7152 Ų5233%0.32925%0.252SS..Hα-helixtrans-59.6-43.5176.3-179.470.8000112.9K600 V601 M602 K608K600-H604 PolarHBondContact O-N 2.84Å; V601-H604 WeakPolarHBondContact O-CB 3.49Å; V601-H604 PolarHBondContact O-N 2.88Å; M602-H604 VanDerWaalsContact C-N 3.3Å; M602-H604 PolarHBondContact O-N 3.47Å; H604-K608 VanDerWaalsContact O-CB 3.29Å; H604-K608 WeakPolarHBondContact O-CB 3.24Å; H604-K608 PolarHBondContact O-N 2.97Å
605V88.1Confident79.4Confident0 Ų059.9 Ų59.90%029%0.288CS..Hα-helixtrans-63-46.2175.6173.10000110.7L574 V601 M602 E603 I609 I610 I644 Y677L574-V605 HydrophobicContact CD1-CG2 4.23Å; L574-V605 HydrophobicContact CD2-CG2 3.83Å; L574-V605 HydrophobicContact CG-CG2 4.42Å; V601-V605 WeakPolarHBondContact O-CG2 3.48Å; V601-V605 PolarHBondContact O-N 2.89Å; M602-V605 PolarHBondContact O-N 3.02Å; E603-V605 PolarHBondContact O-N 2.83Å; V605-I609 HydrophobicContact CG1-CB 4.38Å; V605-I609 HydrophobicContact CG2-CD1 4.2Å; V605-I609 WeakPolarHBondContact O-CA 3.28Å; V605-I609 VanDerWaalsContact O-CB 3.31Å; V605-I609 WeakPolarHBondContact O-CB 3.43Å; V605-I609 PolarHBondContact O-N 2.97Å; V605-I610 HydrophobicContact CG1-CD1 4.17Å; V605-I610 HydrophobicContact CG1-CG1 4.11Å; V605-I610 PolarHBondContact O-N 2.98Å; V605-I644 HydrophobicContact CB-CG2 4.28Å; V605-I644 HydrophobicContact CG1-CD1 4.11Å; V605-I644 HydrophobicContact CG1-CG1 4.5Å; V605-I644 HydrophobicContact CG1-CG2 4.05Å; V605-Y677 HydrophobicContact CG1-CD1 4.42Å; V605-Y677 HydrophobicContact CG1-CD2 3.57Å; V605-Y677 HydrophobicContact CG1-CE2 4.21Å; V605-Y677 HydrophobicContact CG1-CG 3.71Å; V605-Y677 HydrophobicContact CG2-CD1 4.04Å; V605-Y677 HydrophobicContact CG2-CG 3.95Å
606Y86.7Confident77Confident18 Ų1863.8 Ų63.87%0.07132%0.317CS..Iπ-helixtrans-60.3-49.9-178.7-176.6-117.6000111.4M602 E603 N611 M636 L639 A640 K643 I644M602-Y606 WeakPolarHBondContact O-CB 3.37Å; M602-Y606 PolarHBondContact O-N 3.35Å; E603-Y606 PolarHBondContact O-N 2.75Å; Y606-N611 VanDerWaalsContact CE1-ND2 3.28Å; Y606-N611 WeakPolarHBondContact CE1-ND2 3.4Å; Y606-N611 VanDerWaalsContact O-CB 3.27Å; Y606-N611 WeakPolarHBondContact O-CB 3.17Å; Y606-N611 VanDerWaalsContact O-CG 3.23Å; Y606-N611 PolarHBondContact O-N 2.86Å; Y606-N611 PolarHBondContact O-ND2 2.86Å; Y606-M636 HydrophobicContact CD1-CE 3.79Å; Y606-M636 HydrophobicContact CD1-SD 4.45Å; Y606-M636 HydrophobicContact CE1-CE 3.94Å; Y606-M636 HydrophobicContact CE1-SD 4.02Å; Y606-L639 HydrophobicContact CE1-CB 4.24Å; Y606-A640 HydrophobicContact CD1-CB 4.2Å; Y606-A640 HydrophobicContact CG-CB 4.14Å; Y606-K643 HydrophobicContact CD2-CB 4.35Å; Y606-K643 HydrophobicContact CD2-CD 4.33Å; Y606-K643 HydrophobicContact CE2-CB 4.24Å; Y606-K643 HydrophobicContact CE2-CD 3.44Å; Y606-K643 VanDerWaalsContact CE2-CD 3.44Å; Y606-K643 HydrophobicContact CE2-CG 4.44Å; Y606-K643 PolarHBondContact OH-NZ 3.37Å; Y606-I644 HydrophobicContact CD2-CD1 4.31Å; Y606-I644 HydrophobicContact CD2-CG1 4.38Å
607E84.9Confident74.4Confident84 Ų8469.2 Ų69.239%0.39334%0.341SS..Iπ-helixtrans-72.6-47.9-177.7-71.5-177.6-179.400113.8E603 M636E603-E607 WeakPolarHBondContact O-CB 3.39Å; E603-E607 WeakPolarHBondContact O-CG 3.37Å; E603-E607 PolarHBondContact O-N 3.3Å; E607-M636 HydrophobicContact CG-CE 3.5Å; E607-M636 VanDerWaalsContact CG-CE 3.5Å; E607-M636 WeakPolarHBondContact OE1-CE 3.39Å
608K80.8Confident71.5Confident123 Ų12371.9 Ų71.954%0.53536%0.364SS..Iπ-helixtrans-99.9-15.6-165-59.8-61.1-177.1-171.30114.1H604 L612H604-K608 VanDerWaalsContact O-CB 3.29Å; H604-K608 WeakPolarHBondContact O-CB 3.24Å; H604-K608 PolarHBondContact O-N 2.97Å; K608-L612 WeakPolarHBondContact O-CD1 3.4Å
609I74.9Confident68.7Low35 Ų3578.3 Ų78.318%0.17940%0.403CS..Iπ-helixtrans-116.8-47.4-174.9-54.1-177.8000110.8L574 V605 Y677L574-I609 HydrophobicContact CD2-CD1 3.97Å; V605-I609 HydrophobicContact CG1-CB 4.38Å; V605-I609 HydrophobicContact CG2-CD1 4.2Å; V605-I609 WeakPolarHBondContact O-CA 3.28Å; V605-I609 VanDerWaalsContact O-CB 3.31Å; V605-I609 WeakPolarHBondContact O-CB 3.43Å; V605-I609 PolarHBondContact O-N 2.97Å; I609-Y677 HydrophobicContact CD1-CE1 3.93Å; I609-Y677 HydrophobicContact CG2-CE2 3.85Å; I609-Y677 WeakPolarHBondContact CG2-OH 3.48Å
610I71.3Confident66Low34 Ų3480.3 Ų80.317%0.17443%0.428CS..Iπ-helixtrans-92.5-41.5-174.3-56-162.8000112.8V605 L612 D613 I644 Q679V605-I610 HydrophobicContact CG1-CD1 4.17Å; V605-I610 HydrophobicContact CG1-CG1 4.11Å; V605-I610 PolarHBondContact O-N 2.98Å; I610-L612 VanDerWaalsContact C-N 3.29Å; I610-L612 PolarHBondContact O-N 2.77Å; I610-D613 PolarHBondContact O-N 3.38Å; I610-I644 HydrophobicContact CD1-CD1 3.37Å; I610-I644 HydrophobicContact CG1-CD1 4.26Å; I610-Q679 HydrophobicContact CD1-CB 4.35Å
611N66.8Low63.1Low44 Ų4481.5 Ų81.524%0.23545%0.446CS..Hα-helixtrans-74-16.6-179-77.1-15.3000114.4Y606 D613 N614 E615Y606-N611 VanDerWaalsContact CE1-ND2 3.28Å; Y606-N611 WeakPolarHBondContact CE1-ND2 3.4Å; Y606-N611 VanDerWaalsContact O-CB 3.27Å; Y606-N611 WeakPolarHBondContact O-CB 3.17Å; Y606-N611 VanDerWaalsContact O-CG 3.23Å; Y606-N611 PolarHBondContact O-N 2.86Å; Y606-N611 PolarHBondContact O-ND2 2.86Å; N611-D613 VanDerWaalsContact C-N 3.27Å; N611-D613 PolarHBondContact O-N 3.13Å; N611-N614 PolarHBondContact O-N 3.11Å; N611-E615 PolarHBondContact O-N 3.28Å
612L53.2Low60.3Low110 Ų11087.2 Ų87.258%0.57649%0.486SS*.Hα-helixtrans-67.7-25.7174.3-106.3144.5000112.9K608 I610K608-L612 WeakPolarHBondContact O-CD1 3.4Å; I610-L612 VanDerWaalsContact C-N 3.29Å; I610-L612 PolarHBondContact O-N 2.77Å
613D46.2Very low57.9Low126 Ų12691.2 Ų91.267%0.67452%0.52SS*.Hα-helixtrans-77-26175.2-81.3-17.9000112.3I610 N611 S616I610-D613 PolarHBondContact O-N 3.38Å; N611-D613 VanDerWaalsContact C-N 3.27Å; N611-D613 PolarHBondContact O-N 3.13Å; D613-S616 PolarHBondContact O-OG 3.32Å
614N44.4Very low55.5Low119 Ų11997.8 Ų97.864%0.63656%0.556SS**Hα-helixtrans-87.6-23.5-177.5-90.8-14.1000115N611 S616 Q617N611-N614 PolarHBondContact O-N 3.11Å; N614-S616 PolarHBondContact O-N 3.23Å; N614-S616 VanDerWaalsContact O-N 3.15Å; N614-Q617 PolarHBondContact O-N 3.13Å
615E42.8Very low52.9Low173 Ų173101.9 Ų101.981%0.80858%0.58SS**THydrogen-bonded Turntrans-71-4.5176.9-79.7-164.5159.900113.9N611 Q617N611-E615 PolarHBondContact O-N 3.28Å; E615-Q617 PolarHBondContact O-N 2.6Å
616S41.6Very low50.6Low100 Ų100111.4 Ų111.470%0.69962%0.621SS**THydrogen-bonded Turntrans-77.3-517165.70000114.1D613 N614D613-S616 PolarHBondContact O-OG 3.32Å; N614-S616 PolarHBondContact O-N 3.23Å; N614-S616 VanDerWaalsContact O-N 3.15Å
617Q38.9Very low48.4Very low165 Ų165113 Ų11377%0.77163%0.634SS**SBendtrans-141.685.3173.1-69.9-174.52.100111.3N614 E615N614-Q617 PolarHBondContact O-N 3.13Å; E615-Q617 PolarHBondContact O-N 2.6Å
618T32.9Very low46.3Very low135 Ų135111.1 Ų111.183%0.82864%0.637SS**  trans176.5107.3133.632.40000110
619T35.6Very low45Very low134 Ų134113.9 Ų113.982%0.82265%0.652SS**  trans-85.6142.5160.743.10000110.2
620S36.7Very low43.8Very low114 Ų114120 Ų12080%0.79768%0.68SS**  trans76.3132.7175.9790000114.3
621S32.4Very low42.9Very low101 Ų101124.2 Ų124.271%0.70670%0.699SS**  cis-170.4156.933.857.80000113.1
622S34.2Very low42.5Very low123 Ų123127.1 Ų127.186%0.8671%0.709SS**  trans73.2144.4144.4-50.20000121.9
623A41.7Very low42.9Very low90 Ų90127.2 Ų127.274%0.74471%0.707SS**  trans-92.1172.2-160.900000116.2
624N41.2Very low43.6Very low155 Ų155128 Ų12883%0.82971%0.706SS**  trans81.690.1161.2-73.40.1000118.7
625D36.8Very low44.8Very low156 Ų156127.1 Ų127.183%0.83470%0.702SS**  -165.6138.1108.5-111.2-27.5000108.1P627D625-P627 WeakPolarHBondContact O-CD 3.46Å
626K39.1Very low46.3Very low200 Ų200121.4 Ų121.487%0.8768%0.676SS**  trans-99.997.1172.4-86.7-169177.8-174.50108.3
627P39.4Very low48.1Very low52 Ų52117.2 Ų117.234%0.33865%0.647SS.*  trans-64150.9161.517.3-18.5000109.3D625 E631 K632D625-P627 WeakPolarHBondContact O-CD 3.46Å; P627-E631 HydrophobicContact CB-CB 4.26Å; P627-K632 HydrophobicContact CB-CG 4.35Å; P627-K632 VanDerWaalsContact CD-CE 3.49Å; P627-K632 HydrophobicContact CG-CD 4.31Å; P627-K632 VanDerWaalsContact CG-CE 3.47Å; P627-K632 HydrophobicContact CG-CG 3.82Å
628G42.6Very low50.1Low45 Ų45115.8 Ų115.846%0.46464%0.642SS.*  trans-56.7147.4177.800000110.7Q630 E631 K632G628-Q630 PolarHBondContact O-N 3.24Å; G628-E631 PolarHBondContact O-N 3.4Å; G628-K632 PolarHBondContact O-N 2.98Å
629E51.9Low52.5Low180 Ų180112.4 Ų112.484%0.84162%0.618SS**Hα-helixtrans-54.2-29.7-175.8-71.7179.6160.400113.1E633E629-E633 PolarHBondContact O-N 3.24Å
630Q50.9Low54.9Low164 Ų164106 Ų10677%0.76658%0.579SS**Hα-helixtrans-68.7-41.9174.4-95.8170.4-29.900114.4G628 K632 E633 E634G628-Q630 PolarHBondContact O-N 3.24Å; Q630-K632 VanDerWaalsContact C-N 3.32Å; Q630-K632 PolarHBondContact O-N 3.29Å; Q630-E633 PolarHBondContact O-N 2.98Å; Q630-E634 PolarHBondContact O-N 2.77Å; Q630-E634 VanDerWaalsContact O-N 3.1Å
631E51.8Low57.2Low122 Ų122103.3 Ų103.357%0.5755%0.554SS**Hα-helixtrans-66.5-37.1178.9-75.1178.5156.500111.1P627 G628 E633 D635P627-E631 HydrophobicContact CB-CB 4.26Å; G628-E631 PolarHBondContact O-N 3.4Å; E631-E633 PolarHBondContact O-N 3.23Å; E631-D635 WeakPolarHBondContact O-CB 3.28Å; E631-D635 PolarHBondContact O-N 3.06Å
632K58.9Low59.8Low105 Ų105105 Ų10546%0.45755%0.551SS.*Hα-helixtrans-65.8-36.7175.1-72.4-171178.3-175.20113.1P627 G628 Q630 M636P627-K632 HydrophobicContact CB-CG 4.35Å; P627-K632 VanDerWaalsContact CD-CE 3.49Å; P627-K632 HydrophobicContact CG-CD 4.31Å; P627-K632 VanDerWaalsContact CG-CE 3.47Å; P627-K632 HydrophobicContact CG-CG 3.82Å; G628-K632 PolarHBondContact O-N 2.98Å; Q630-K632 VanDerWaalsContact C-N 3.32Å; Q630-K632 PolarHBondContact O-N 3.29Å; K632-M636 WeakPolarHBondContact O-CB 3.46Å; K632-M636 WeakPolarHBondContact O-CG 3.35Å; K632-M636 PolarHBondContact O-N 2.98Å; K632-M636 VanDerWaalsContact O-N 3.11Å
633E60.2Low62.3Low112 Ų112103 Ų10352%0.52353%0.526SS..Hα-helixtrans-72.2-38.2-179.6-150-176.4166.900111.3K600 E629 Q630 E631 A637K600-E633 IonicContact NZ-OE1 3.47Å; K600-E633 PolarHBondContact NZ-OE1 2.75Å; K600-E633 VanDerWaalsContact NZ-OE1 3.14Å; E629-E633 PolarHBondContact O-N 3.24Å; Q630-E633 PolarHBondContact O-N 2.98Å; E631-E633 PolarHBondContact O-N 3.23Å; E633-A637 WeakPolarHBondContact O-CB 3.43Å; E633-A637 PolarHBondContact O-N 3.27Å
634E62.2Low64.6Low143 Ų14398.7 Ų98.767%0.66849%0.491SS*.Hα-helixtrans-67.7-43.2174.3-73.9-171.8161.800112.7Q630 M636 A637 M638Q630-E634 PolarHBondContact O-N 2.77Å; Q630-E634 VanDerWaalsContact O-N 3.1Å; E634-M636 VanDerWaalsContact C-N 3.32Å; E634-M636 PolarHBondContact O-N 3.26Å; E634-A637 PolarHBondContact O-N 2.93Å; E634-M638 WeakPolarHBondContact O-CG 3.35Å; E634-M638 PolarHBondContact O-N 2.93Å
635D69.1Low67Low101 Ų10193.2 Ų93.254%0.5446%0.46SS..Hα-helixtrans-61.5-40.6175.1-89.5-15.6000111.9E631 M638 L639E631-D635 WeakPolarHBondContact O-CB 3.28Å; E631-D635 PolarHBondContact O-N 3.06Å; D635-M638 PolarHBondContact O-N 3.46Å; D635-L639 WeakPolarHBondContact O-CB 3.24Å; D635-L639 WeakPolarHBondContact O-CD1 3.3Å; D635-L639 VanDerWaalsContact O-CG 3.29Å; D635-L639 WeakPolarHBondContact O-CG 3.41Å; D635-L639 PolarHBondContact O-N 2.59Å
636M74.4Confident69.7Low53 Ų5385.9 Ų85.926%0.26142%0.421SS..Hα-helixtrans-67.2-42.4177.5-85.7-68.5-6600113Y606 E607 K632 E634 M638 L639 A640Y606-M636 HydrophobicContact CD1-CE 3.79Å; Y606-M636 HydrophobicContact CD1-SD 4.45Å; Y606-M636 HydrophobicContact CE1-CE 3.94Å; Y606-M636 HydrophobicContact CE1-SD 4.02Å; E607-M636 HydrophobicContact CG-CE 3.5Å; E607-M636 VanDerWaalsContact CG-CE 3.5Å; E607-M636 WeakPolarHBondContact OE1-CE 3.39Å; K632-M636 WeakPolarHBondContact O-CB 3.46Å; K632-M636 WeakPolarHBondContact O-CG 3.35Å; K632-M636 PolarHBondContact O-N 2.98Å; K632-M636 VanDerWaalsContact O-N 3.11Å; E634-M636 VanDerWaalsContact C-N 3.32Å; E634-M636 PolarHBondContact O-N 3.26Å; M636-M638 VanDerWaalsContact C-N 3.31Å; M636-M638 PolarHBondContact O-N 3.15Å; M636-L639 PolarHBondContact O-N 3.21Å; M636-A640 WeakPolarHBondContact O-CB 3.36Å; M636-A640 PolarHBondContact O-N 2.88Å
637A78.1Confident72.2Confident12 Ų1276.7 Ų76.710%0.09938%0.382CS..Hα-helixtrans-59.3-43.5175.300000111.5E603 E633 E634 E641E603-A637 WeakPolarHBondContact OE1-CB 3.28Å; E633-A637 WeakPolarHBondContact O-CB 3.43Å; E633-A637 PolarHBondContact O-N 3.27Å; E634-A637 PolarHBondContact O-N 2.93Å; A637-E641 WeakPolarHBondContact O-CB 3.48Å; A637-E641 PolarHBondContact O-N 3.4Å
638M81.9Confident74.8Confident134 Ų13474.2 Ų74.266%0.6637%0.366SS*.Hα-helixtrans-64.2-45.7176-70-121.3-70.300112E634 D635 M636 A640 E641 E642E634-M638 WeakPolarHBondContact O-CG 3.35Å; E634-M638 PolarHBondContact O-N 2.93Å; D635-M638 PolarHBondContact O-N 3.46Å; M636-M638 VanDerWaalsContact C-N 3.31Å; M636-M638 PolarHBondContact O-N 3.15Å; M638-A640 PolarHBondContact O-N 3.04Å; M638-E641 PolarHBondContact O-N 3.29Å; M638-E642 WeakPolarHBondContact O-CB 3.27Å; M638-E642 PolarHBondContact O-N 3.28Å
639L84Confident77.1Confident64 Ų6475.3 Ų75.334%0.33536%0.358SS..Hα-helixtrans-62.5-41.7177.8-77.2163.5000112.7Y606 D635 M636 E641 E642 K643Y606-L639 HydrophobicContact CE1-CB 4.24Å; D635-L639 WeakPolarHBondContact O-CB 3.24Å; D635-L639 WeakPolarHBondContact O-CD1 3.3Å; D635-L639 VanDerWaalsContact O-CG 3.29Å; D635-L639 WeakPolarHBondContact O-CG 3.41Å; D635-L639 PolarHBondContact O-N 2.59Å; M636-L639 PolarHBondContact O-N 3.21Å; L639-E641 VanDerWaalsContact C-N 3.34Å; L639-E642 PolarHBondContact O-N 3.47Å; L639-K643 WeakPolarHBondContact O-CB 3.36Å; L639-K643 WeakPolarHBondContact O-CG 3.38Å; L639-K643 PolarHBondContact O-N 3.24Å
640A84.9Confident78.9Confident0 Ų072.6 Ų72.60%035%0.35CS..Hα-helixtrans-64.9-40.5176.500000111.2E603 Y606 M636 M638 K643 I644E603-A640 HydrophobicContact CB-CB 4.46Å; E603-A640 HydrophobicContact CG-CB 3.96Å; Y606-A640 HydrophobicContact CD1-CB 4.2Å; Y606-A640 HydrophobicContact CG-CB 4.14Å; M636-A640 WeakPolarHBondContact O-CB 3.36Å; M636-A640 PolarHBondContact O-N 2.88Å; M638-A640 PolarHBondContact O-N 3.04Å; A640-K643 PolarHBondContact O-N 2.92Å; A640-I644 VanDerWaalsContact O-CB 3.27Å; A640-I644 WeakPolarHBondContact O-CB 3.41Å; A640-I644 WeakPolarHBondContact O-CG1 3.35Å; A640-I644 PolarHBondContact O-N 2.81Å
641E86.2Confident80.9Confident58 Ų5869.5 Ų69.527%0.27134%0.335SS..Hα-helixtrans-67.6-35.2176.6-169.3169156.500112.8R599 M602 A637 M638 L639 P655 K680R599-E641 IonicContact CZ-OE2 3.76Å; R599-E641 IonicContact NE-OE2 3.03Å; R599-E641 PolarHBondContact NE-OE2 3.44Å; R599-E641 IonicContact NH2-OE1 3.74Å; R599-E641 IonicContact NH2-OE2 2.77Å; R599-E641 PolarHBondContact NH2-OE2 3.18Å; M602-E641 HydrophobicContact CE-CB 4.38Å; M602-E641 HydrophobicContact CE-CG 4.25Å; A637-E641 WeakPolarHBondContact O-CB 3.48Å; A637-E641 PolarHBondContact O-N 3.4Å; M638-E641 PolarHBondContact O-N 3.29Å; L639-E641 VanDerWaalsContact C-N 3.34Å; E641-P655 HydrophobicContact CG-CG 3.98Å; E641-K680 PolarHBondContact O-NZ 3.08Å
642E86.1Confident82.9Confident135 Ų13567.2 Ų67.263%0.63133%0.329SS*.Hα-helixtrans-71.3-32176-168.1-177.1-17600112.7M638 L639 K680M638-E642 WeakPolarHBondContact O-CB 3.27Å; M638-E642 PolarHBondContact O-N 3.28Å; L639-E642 PolarHBondContact O-N 3.47Å; E642-K680 VanDerWaalsContact O-CD 3.28Å; E642-K680 WeakPolarHBondContact O-CD 3.46Å
643K86.7Confident84.6Confident81 Ų8162.6 Ų62.635%0.35231%0.31SS..Hα-helixtrans-101.4-24.1-172.6-70.4-177.1174.5-173.50115Y606 L639 A640 Q679 K680Y606-K643 HydrophobicContact CD2-CB 4.35Å; Y606-K643 HydrophobicContact CD2-CD 4.33Å; Y606-K643 HydrophobicContact CE2-CB 4.24Å; Y606-K643 HydrophobicContact CE2-CD 3.44Å; Y606-K643 VanDerWaalsContact CE2-CD 3.44Å; Y606-K643 HydrophobicContact CE2-CG 4.44Å; Y606-K643 PolarHBondContact OH-NZ 3.37Å; L639-K643 WeakPolarHBondContact O-CB 3.36Å; L639-K643 WeakPolarHBondContact O-CG 3.38Å; L639-K643 PolarHBondContact O-N 3.24Å; A640-K643 PolarHBondContact O-N 2.92Å; K643-Q679 CarbonylContact O-C 3.57Å; K643-Q679 WeakPolarHBondContact O-CA 3.38Å; K643-Q679 WeakPolarHBondContact O-CG 3.39Å; K643-K680 PolarHBondContact O-N 3.11Å
644I89.5Confident86.2Confident1 Ų161 Ų611%0.00531%0.305CS..EExtended strand (participates in β ladder)trans-112.4141.6-173.3-51.2-58.3000110.8M602 V605 Y606 I610 A640 K680M602-I644 HydrophobicContact CB-CB 4.31Å; M602-I644 HydrophobicContact CB-CG2 4.28Å; M602-I644 HydrophobicContact CE-CB 4.38Å; M602-I644 WeakPolarHBondContact CE-O 3.23Å; M602-I644 HydrophobicContact CG-CG2 4.37Å; V605-I644 HydrophobicContact CB-CG2 4.28Å; V605-I644 HydrophobicContact CG1-CD1 4.11Å; V605-I644 HydrophobicContact CG1-CG1 4.5Å; V605-I644 HydrophobicContact CG1-CG2 4.05Å; Y606-I644 HydrophobicContact CD2-CD1 4.31Å; Y606-I644 HydrophobicContact CD2-CG1 4.38Å; I610-I644 HydrophobicContact CD1-CD1 3.37Å; I610-I644 HydrophobicContact CG1-CD1 4.26Å; A640-I644 VanDerWaalsContact O-CB 3.27Å; A640-I644 WeakPolarHBondContact O-CB 3.41Å; A640-I644 WeakPolarHBondContact O-CG1 3.35Å; A640-I644 PolarHBondContact O-N 2.81Å; I644-K680 WeakPolarHBondContact O-CE 3.49Å
645E91.3Very high87.7Confident39 Ų3955 Ų5518%0.18228%0.278CS..EExtended strand (participates in β ladder)trans-113131.4160.6-85.8174.2171.600109.9V652 Y677 R678 K680E645-V652 HydrophobicContact CG-CG1 4.47Å; E645-Y677 VanDerWaalsContact O-CA 3.32Å; E645-Y677 WeakPolarHBondContact O-CA 3.43Å; E645-R678 HydrophobicContact CB-CG 3.96Å; E645-R678 PolarHBondContact N-O 3.11Å; E645-R678 PolarHBondContact O-N 2.92Å; E645-R678 IonicContact OE2-CZ 3.15Å; E645-R678 IonicContact OE2-NE 3.6Å; E645-R678 PolarHBondContact OE2-NE 2.61Å; E645-R678 IonicContact OE2-NH2 2.71Å; E645-R678 PolarHBondContact OE2-NH2 2.65Å; E645-K680 HydrophobicContact CB-CG 4.4Å; E645-K680 HydrophobicContact CG-CD 4.02Å; E645-K680 HydrophobicContact CG-CG 3.53Å
646L93.5Very high88.8Confident2 Ų254.6 Ų54.61%0.0128%0.276CS..EExtended strand (participates in β ladder)trans-106.6136.2169.9-152.370.4000109.7L574 V598 V601 M602 L653 L675 H676L574-L646 HydrophobicContact CD1-CD1 3.95Å; V598-L646 HydrophobicContact CG1-CB 4.1Å; V598-L646 HydrophobicContact CG1-CD2 3.81Å; V601-L646 HydrophobicContact CB-CD2 3.81Å; V601-L646 HydrophobicContact CG1-CD1 4.24Å; V601-L646 HydrophobicContact CG1-CD2 3.73Å; M602-L646 HydrophobicContact CG-CB 4Å; L646-L653 HydrophobicContact CB-CD1 4.42Å; L646-L653 HydrophobicContact CD2-CD1 4.2Å; L646-L653 HydrophobicContact CG-CD1 4.25Å; L646-L653 WeakPolarHBondContact O-CB 3.28Å; L646-L653 PolarHBondContact O-N 3.46Å; L646-L675 HydrophobicContact CD1-CB 4.42Å; L646-L675 HydrophobicContact CD2-CB 4.48Å; L646-L675 HydrophobicContact CD2-CD1 3.91Å; L646-L675 HydrophobicContact CG-CB 4.39Å; L646-H676 CarbonylContact C-O 3.6Å; L646-H676 WeakPolarHBondContact CA-O 3.26Å
647M93Very high89.6Confident8 Ų853.5 Ų53.54%0.03927%0.271CS..EExtended strand (participates in β ladder)trans-132.9147.6-172.5-59176.269.900111.1D650 Q651 V652 L675 H676M647-D650 WeakPolarHBondContact CE-O 3.44Å; M647-Q651 CarbonylContact C-O 3.56Å; M647-Q651 WeakPolarHBondContact CA-O 3.22Å; M647-V652 HydrophobicContact CG-CG2 4.28Å; M647-L675 CarbonylContact O-C 3.59Å; M647-L675 WeakPolarHBondContact O-CA 3.3Å; M647-H676 HydrophobicContact CB-CB 4.35Å; M647-H676 PolarHBondContact N-O 2.78Å; M647-H676 PolarHBondContact O-N 2.91Å
648C94.5Very high90.4Very high0 Ų053.8 Ų53.80%027%0.271CS..EExtended strand (participates in β ladder)trans-134.9126.5169.3-175.70000107.8D650 Q651 L653 V662 I666 L675C648-D650 VanDerWaalsContact C-N 3.31Å; C648-D650 PolarHBondContact O-N 2.98Å; C648-Q651 PolarHBondContact N-O 2.8Å; C648-Q651 WeakPolarHBondContact O-CB 3.34Å; C648-Q651 PolarHBondContact O-N 3.23Å; C648-L653 HydrophobicContact CB-CD1 4.14Å; C648-L653 HydrophobicContact CB-CD2 3.86Å; C648-L653 HydrophobicContact CB-CG 4.33Å; C648-V662 HydrophobicContact CB-CG1 3.89Å; C648-I666 HydrophobicContact CB-CG2 3.82Å; C648-I666 WeakPolarHBondContact O-CG2 3.48Å; C648-L675 HydrophobicContact CB-CD2 4.07Å
649Q90.8Very high91.1Very high67 Ų6747.4 Ų47.431%0.31324%0.239SC..THydrogen-bonded Turntrans48.949.7-175.2-57.6-162.3-33.700113.5Q651 I666 W667 K668 S669Q649-Q651 PolarHBondContact O-N 2.88Å; Q649-I666 PolarHBondContact OE1-O 3.27Å; Q649-W667 HydrophobicContact CG-CE3 3.93Å; Q649-W667 HydrophobicContact CG-CZ3 4.26Å; Q649-K668 VanDerWaalsContact CD-N 3.32Å; Q649-S669 PolarHBondContact NE2-OG 3.15Å
650D88.8Confident91.6Very high124 Ų12445 Ų4566%0.66323%0.225SC*.THydrogen-bonded Turntrans60.98.5-179.2-52.5-40.4000115.5H577 M647 C648H577-D650 IonicContact NE2-OD1 2.92Å; M647-D650 WeakPolarHBondContact CE-O 3.44Å; C648-D650 VanDerWaalsContact C-N 3.31Å; C648-D650 PolarHBondContact O-N 2.98Å
651Q93.1Very high92.1Very high98 Ų9845.1 Ų45.146%0.45823%0.227SC..EExtended strand (participates in β ladder)trans-98.6129.6172.9-174178.7-400110.7M647 C648 Q649 I666M647-Q651 CarbonylContact C-O 3.56Å; M647-Q651 WeakPolarHBondContact CA-O 3.22Å; C648-Q651 PolarHBondContact N-O 2.8Å; C648-Q651 WeakPolarHBondContact O-CB 3.34Å; C648-Q651 PolarHBondContact O-N 3.23Å; Q649-Q651 PolarHBondContact O-N 2.88Å; Q651-I666 HydrophobicContact CB-CG2 4.3Å
652V93.9Very high92.6Very high74 Ų7442.4 Ų42.445%0.44821%0.214SC..EExtended strand (participates in β ladder)trans-67.8132.6172.4-178.60000109.7E645 M647E645-V652 HydrophobicContact CG-CG1 4.47Å; M647-V652 HydrophobicContact CG-CG2 4.28Å
653L94.9Very high93Very high8 Ų839.5 Ų39.54%0.04220%0.199CC..PPolyproline II helixtrans-90.8140.4-176.8-59.4-179000111.5V598 L646 C648 V662 I666 L675V598-L653 HydrophobicContact CG1-CB 3.87Å; V598-L653 HydrophobicContact CG1-CD1 4.43Å; V598-L653 HydrophobicContact CG2-CB 4.19Å; V598-L653 HydrophobicContact CG2-CD1 4.08Å; L646-L653 HydrophobicContact CB-CD1 4.42Å; L646-L653 HydrophobicContact CD2-CD1 4.2Å; L646-L653 HydrophobicContact CG-CD1 4.25Å; L646-L653 WeakPolarHBondContact O-CB 3.28Å; L646-L653 PolarHBondContact O-N 3.46Å; C648-L653 HydrophobicContact CB-CD1 4.14Å; C648-L653 HydrophobicContact CB-CD2 3.86Å; C648-L653 HydrophobicContact CB-CG 4.33Å; L653-V662 HydrophobicContact CD1-CG1 3.94Å; L653-V662 HydrophobicContact CD1-CG2 4.17Å; L653-V662 HydrophobicContact CD2-CG1 3.83Å; L653-V662 HydrophobicContact CD2-CG2 4.08Å; L653-I666 HydrophobicContact CD2-CD1 3.41Å; L653-I666 VanDerWaalsContact CD2-CD1 3.41Å; L653-L675 HydrophobicContact CD1-CD2 3.81Å
654D93.7Very high93.3Very high78 Ų7839.9 Ų39.942%0.41720%0.202SC..PPolyproline II helixtrans-68.7125.5167.7-179.5-17.5000109.2V598 N656 M657V598-D654 WeakPolarHBondContact CB-O 3.44Å; D654-N656 PolarHBondContact O-N 2.87Å; D654-N656 VanDerWaalsContact O-N 3.1Å; D654-N656 WeakPolarHBondContact OD1-CB 3.28Å; D654-N656 PolarHBondContact OD1-N 3.05Å; D654-N656 PolarHBondContact OD1-ND2 3.13Å; D654-N656 VanDerWaalsContact OD1-ND2 3.1Å; D654-M657 HydrophobicContact CB-CG 4.05Å; D654-M657 HydrophobicContact CB-SD 4.4Å; D654-M657 WeakPolarHBondContact O-CB 3.43Å; D654-M657 PolarHBondContact O-N 2.98Å
655P93Very high93.6Very high18 Ų1842.1 Ų42.112%0.11721%0.212CC..THydrogen-bonded Turntrans-54.9-27178.6-26.836000114.4V598 R599 M602 E641V598-P655 PolarHBondContact N-O 3.1Å; R599-P655 HydrophobicContact CB-CB 3.99Å; R599-P655 PolarHBondContact N-O 3.42Å; M602-P655 HydrophobicContact CE-CG 4.43Å; M602-P655 HydrophobicContact SD-CB 4.12Å; M602-P655 HydrophobicContact SD-CG 4.05Å; E641-P655 HydrophobicContact CG-CG 3.98Å
656N91.6Very high93.8Very high93 Ų9340.6 Ų40.650%0.49721%0.205SC..THydrogen-bonded Turntrans-83.2-13.6-179.3-57.8-64.3000113.5D654D654-N656 PolarHBondContact O-N 2.87Å; D654-N656 VanDerWaalsContact O-N 3.1Å; D654-N656 WeakPolarHBondContact OD1-CB 3.28Å; D654-N656 PolarHBondContact OD1-N 3.05Å; D654-N656 PolarHBondContact OD1-ND2 3.13Å; D654-N656 VanDerWaalsContact OD1-ND2 3.1Å
657M93.1Very high93.8Very high29 Ų2942.1 Ų42.114%0.14321%0.211CC..SBendtrans-67.5145.6175.1-82.8-174.8156.500111.2M417 Q597 V598 D654 T661 V662 I666M417-M657 HydrophobicContact CB-CE 4.39Å; M417-M657 HydrophobicContact CE-CE 3.76Å; M417-M657 HydrophobicContact CG-CE 3.71Å; M417-M657 HydrophobicContact SD-CE 3.55Å; M417-M657 VanDerWaalsContact SD-CE 3.55Å; Q597-M657 CarbonylContact C-O 3.6Å; Q597-M657 WeakPolarHBondContact CA-O 3.29Å; V598-M657 HydrophobicContact CG2-CB 4.28Å; V598-M657 WeakPolarHBondContact CG2-O 3.32Å; V598-M657 PolarHBondContact N-O 3.33Å; D654-M657 HydrophobicContact CB-CG 4.05Å; D654-M657 HydrophobicContact CB-SD 4.4Å; D654-M657 WeakPolarHBondContact O-CB 3.43Å; D654-M657 PolarHBondContact O-N 2.98Å; M657-T661 HydrophobicContact CE-CG2 3.92Å; M657-T661 HydrophobicContact CG-CG2 4.4Å; M657-T661 HydrophobicContact SD-CG2 4.36Å; M657-V662 HydrophobicContact CB-CG2 4.1Å; M657-V662 HydrophobicContact SD-CG2 4.38Å; M657-I666 HydrophobicContact SD-CD1 4.19Å
658D94.4Very high93.8Very high18 Ų1848.2 Ų48.210%0.09624%0.237CC..BIsolated β-bridgetrans-89.7157.4170.766.321.6000112.3L596 R660 T661 V662L596-D658 CarbonylContact O-C 3.56Å; L596-D658 VanDerWaalsContact O-CA 3.32Å; L596-D658 WeakPolarHBondContact O-CA 3.33Å; D658-R660 VanDerWaalsContact CG-CG 3.48Å; D658-R660 PolarHBondContact O-N 3.42Å; D658-R660 WeakPolarHBondContact OD1-CG 3.46Å; D658-R660 IonicContact OD1-NE 2.79Å; D658-R660 IonicContact OD2-CZ 2.74Å; D658-R660 IonicContact OD2-NE 2.75Å; D658-R660 PolarHBondContact OD2-NE 3.43Å; D658-R660 IonicContact OD2-NH2 3.48Å; D658-R660 PolarHBondContact OD2-NH2 2.97Å; D658-T661 PolarHBondContact O-N 3.19Å; D658-T661 VanDerWaalsContact O-N 3.1Å; D658-T661 WeakPolarHBondContact OD1-CA 3.34Å; D658-T661 WeakPolarHBondContact OD1-CB 3.37Å; D658-T661 PolarHBondContact OD1-N 3.24Å; D658-T661 PolarHBondContact OD1-OG1 3.2Å; D658-V662 WeakPolarHBondContact O-CG2 3.49Å; D658-V662 PolarHBondContact O-N 3.41Å
659L95.7Very high93.6Very high0 Ų052.2 Ų52.20%027%0.265CS..Hα-helixtrans-57.7-35.2-176.8-71.4-174.6000113.2I570 F572 A592 L596 V601 K663 L673 L675I570-L659 HydrophobicContact CD1-CB 4.37Å; F572-L659 HydrophobicContact CD1-CD1 3.96Å; F572-L659 HydrophobicContact CE1-CD1 3.79Å; F572-L659 HydrophobicContact CZ-CD1 4.4Å; A592-L659 HydrophobicContact CB-CD1 4.15Å; L596-L659 HydrophobicContact CB-CD1 4.06Å; L596-L659 HydrophobicContact CB-CG 4.26Å; L596-L659 HydrophobicContact CD2-CD1 4.27Å; L596-L659 WeakPolarHBondContact O-CG 3.41Å; L596-L659 PolarHBondContact O-N 3.33Å; V601-L659 HydrophobicContact CG2-CD2 4.19Å; L659-K663 VanDerWaalsContact O-CB 3.29Å; L659-K663 WeakPolarHBondContact O-CB 3.24Å; L659-K663 PolarHBondContact O-N 2.84Å; L659-L673 HydrophobicContact CB-CD2 4.4Å; L659-L673 HydrophobicContact CD2-CD2 4.09Å; L659-L675 HydrophobicContact CD2-CD1 3.77Å
660R95.1Very high93.2Very high13 Ų1351.4 Ų51.45%0.04928%0.275CS..Hα-helixtrans-69.1-36.4177.565.4-176.3176.2-176.55.8112.7Y419 W446 I570 D594 D658 K663 H664Y419-R660 HydrophobicContact CD1-CB 3.96Å; Y419-R660 HydrophobicContact CD1-CG 4.09Å; Y419-R660 WeakPolarHBondContact O-CD 3.26Å; Y419-R660 PolarHBondContact O-NE 3.4Å; W446-R660 VanDerWaalsContact O-CZ 3.3Å; W446-R660 PolarHBondContact O-NH1 3.08Å; W446-R660 PolarHBondContact O-NH2 3.26Å; I570-R660 HydrophobicContact CD1-CB 3.72Å; D594-R660 HydrophobicContact CB-CB 4.25Å; D594-R660 WeakPolarHBondContact O-CG 3.47Å; D594-R660 PolarHBondContact O-N 3.34Å; D594-R660 VanDerWaalsContact O-N 3.14Å; D594-R660 WeakPolarHBondContact OD2-CD 3.44Å; D594-R660 IonicContact OD2-NH1 3.55Å; D594-R660 PolarHBondContact OD2-NH1 2.88Å; D658-R660 VanDerWaalsContact CG-CG 3.48Å; D658-R660 PolarHBondContact O-N 3.42Å; D658-R660 WeakPolarHBondContact OD1-CG 3.46Å; D658-R660 IonicContact OD1-NE 2.79Å; D658-R660 IonicContact OD2-CZ 2.74Å; D658-R660 IonicContact OD2-NE 2.75Å; D658-R660 PolarHBondContact OD2-NE 3.43Å; D658-R660 IonicContact OD2-NH2 3.48Å; D658-R660 PolarHBondContact OD2-NH2 2.97Å; R660-K663 PolarHBondContact O-N 2.86Å; R660-H664 VanDerWaalsContact O-CB 3.32Å; R660-H664 WeakPolarHBondContact O-CB 3.36Å; R660-H664 PolarHBondContact O-N 3.04Å
661T95.3Very high93.3Very high4 Ų448.4 Ų48.43%0.02527%0.273CS..Hα-helixtrans-66.6-44.6174.9-620000110.2M417 Y419 M657 D658 K663 H664 F665M417-T661 WeakPolarHBondContact O-CG2 3.4Å; Y419-T661 PolarHBondContact N-OG1 3.41Å; M657-T661 HydrophobicContact CE-CG2 3.92Å; M657-T661 HydrophobicContact CG-CG2 4.4Å; M657-T661 HydrophobicContact SD-CG2 4.36Å; D658-T661 PolarHBondContact O-N 3.19Å; D658-T661 VanDerWaalsContact O-N 3.1Å; D658-T661 WeakPolarHBondContact OD1-CA 3.34Å; D658-T661 WeakPolarHBondContact OD1-CB 3.37Å; D658-T661 PolarHBondContact OD1-N 3.24Å; D658-T661 PolarHBondContact OD1-OG1 3.2Å; T661-K663 VanDerWaalsContact C-N 3.34Å; T661-K663 PolarHBondContact O-N 3.48Å; T661-H664 PolarHBondContact O-N 3.19Å; T661-F665 HydrophobicContact CG2-CD2 3.79Å; T661-F665 HydrophobicContact CG2-CE2 4.29Å; T661-F665 PolarHBondContact O-N 3.46Å
662V96.1Very high93.3Very high0 Ų045.6 Ų45.60%026%0.261CS..Iπ-helixtrans-58.7-47.3173.41780000110.6V598 C648 L653 M657 D658 H664 I666 W667 L673 L675V598-V662 HydrophobicContact CG2-CG2 3.85Å; C648-V662 HydrophobicContact CB-CG1 3.89Å; L653-V662 HydrophobicContact CD1-CG1 3.94Å; L653-V662 HydrophobicContact CD1-CG2 4.17Å; L653-V662 HydrophobicContact CD2-CG1 3.83Å; L653-V662 HydrophobicContact CD2-CG2 4.08Å; M657-V662 HydrophobicContact CB-CG2 4.1Å; M657-V662 HydrophobicContact SD-CG2 4.38Å; D658-V662 WeakPolarHBondContact O-CG2 3.49Å; D658-V662 PolarHBondContact O-N 3.41Å; V662-H664 VanDerWaalsContact C-N 3.3Å; V662-H664 PolarHBondContact O-N 3.36Å; V662-I666 HydrophobicContact CG1-CB 4.37Å; V662-I666 HydrophobicContact CG1-CD1 4.45Å; V662-I666 WeakPolarHBondContact O-CA 3.33Å; V662-I666 WeakPolarHBondContact O-CB 3.45Å; V662-I666 PolarHBondContact O-N 3.27Å; V662-W667 PolarHBondContact O-N 2.94Å; V662-L673 HydrophobicContact CG1-CD1 4.05Å; V662-L675 HydrophobicContact CG1-CD2 4.14Å
663K95.1Very high93.3Very high74 Ų7442 Ų4232%0.32224%0.24SC..Iπ-helixtrans-62.5-35.3178.9-172.9175.4-179.7178.10112.8I570 L659 R660 T661 L673I570-K663 HydrophobicContact CD1-CD 4.27Å; I570-K663 HydrophobicContact CG2-CD 4.11Å; L659-K663 VanDerWaalsContact O-CB 3.29Å; L659-K663 WeakPolarHBondContact O-CB 3.24Å; L659-K663 PolarHBondContact O-N 2.84Å; R660-K663 PolarHBondContact O-N 2.86Å; T661-K663 VanDerWaalsContact C-N 3.34Å; T661-K663 PolarHBondContact O-N 3.48Å; K663-L673 HydrophobicContact CB-CD1 4.41Å; K663-L673 HydrophobicContact CB-CD2 4.42Å; K663-L673 HydrophobicContact CD-CB 4.46Å; K663-L673 HydrophobicContact CG-CB 4.45Å
664H93.9Very high93.3Very high89 Ų8942.3 Ų42.341%0.41224%0.242SC..Iπ-helixtrans-79.4-50.4-177.8-172.978.3000112.5Y419 R660 T661 V662 K668Y419-H664 HydrophobicContact CD1-CB 4.02Å; Y419-H664 HydrophobicContact CD2-CB 3.77Å; Y419-H664 AromaticContact CD2-CD2 3.46Å; Y419-H664 VanDerWaalsContact CD2-CD2 3.46Å; Y419-H664 WeakPolarHBondContact CD2-CD2 3.5Å; Y419-H664 AromaticContact CD2-CE1 3.61Å; Y419-H664 AromaticContact CD2-CG 3.24Å; Y419-H664 AromaticContact CD2-ND1 3.35Å; Y419-H664 VanDerWaalsContact CD2-ND1 3.35Å; Y419-H664 WeakPolarHBondContact CD2-ND1 3.37Å; Y419-H664 AromaticContact CD2-NE2 3.69Å; Y419-H664 HydrophobicContact CE2-CB 4.31Å; Y419-H664 AromaticContact CE2-CE1 3.41Å; Y419-H664 VanDerWaalsContact CE2-CE1 3.41Å; Y419-H664 WeakPolarHBondContact CE2-CE1 3.47Å; Y419-H664 AromaticContact CE2-CG 3.64Å; Y419-H664 AromaticContact CE2-ND1 3.19Å; Y419-H664 WeakPolarHBondContact CE2-ND1 3.49Å; Y419-H664 AromaticContact CE2-NE2 3.96Å; Y419-H664 HydrophobicContact CG-CB 3.59Å; Y419-H664 AromaticContact CG-CG 3.64Å; Y419-H664 AromaticContact CZ-ND1 3.81Å; R660-H664 VanDerWaalsContact O-CB 3.32Å; R660-H664 WeakPolarHBondContact O-CB 3.36Å; R660-H664 PolarHBondContact O-N 3.04Å; T661-H664 PolarHBondContact O-N 3.19Å; V662-H664 VanDerWaalsContact C-N 3.3Å; V662-H664 PolarHBondContact O-N 3.36Å; H664-K668 PolarHBondContact O-NZ 3.44Å; H664-K668 VanDerWaalsContact O-NZ 3.16Å
665F94.3Very high93.4Very high48 Ų4838.6 Ų38.621%0.21122%0.222CC..Iπ-helixtrans-88.1-39.7-172-74.6-78000113.4F415 M417 V418 T661 K668F415-F665 HydrophobicContact CE2-CE1 4.36Å; F415-F665 HydrophobicContact CZ-CE1 4.02Å; F415-F665 HydrophobicContact CZ-CZ 4.39Å; M417-F665 HydrophobicContact CE-CB 3.55Å; M417-F665 HydrophobicContact CE-CD1 4.43Å; M417-F665 HydrophobicContact CE-CG 4Å; M417-F665 HydrophobicContact CG-CD1 4.45Å; M417-F665 HydrophobicContact CG-CD2 4.19Å; M417-F665 HydrophobicContact CG-CE2 4.43Å; M417-F665 HydrophobicContact CG-CG 4.19Å; V418-F665 WeakPolarHBondContact O-CE2 3.34Å; T661-F665 HydrophobicContact CG2-CD2 3.79Å; T661-F665 HydrophobicContact CG2-CE2 4.29Å; T661-F665 PolarHBondContact O-N 3.46Å; F665-K668 WeakPolarHBondContact O-CE 3.45Å; F665-K668 PolarHBondContact O-NZ 2.86Å
666I95.3Very high93.3Very high8 Ų839.8 Ų39.84%0.04123%0.226CC..Iπ-helixtrans-100.9-43.6-168.7-55.4174000111.1M417 C648 Q649 Q651 L653 M657 V662 K668M417-I666 HydrophobicContact CE-CG1 4.32Å; C648-I666 HydrophobicContact CB-CG2 3.82Å; C648-I666 WeakPolarHBondContact O-CG2 3.48Å; Q649-I666 PolarHBondContact OE1-O 3.27Å; Q651-I666 HydrophobicContact CB-CG2 4.3Å; L653-I666 HydrophobicContact CD2-CD1 3.41Å; L653-I666 VanDerWaalsContact CD2-CD1 3.41Å; M657-I666 HydrophobicContact SD-CD1 4.19Å; V662-I666 HydrophobicContact CG1-CB 4.37Å; V662-I666 HydrophobicContact CG1-CD1 4.45Å; V662-I666 WeakPolarHBondContact O-CA 3.33Å; V662-I666 WeakPolarHBondContact O-CB 3.45Å; V662-I666 PolarHBondContact O-N 3.27Å; I666-K668 PolarHBondContact O-N 3.47Å
667W95.4Very high93.3Very high34 Ų3436.2 Ų36.213%0.12921%0.205CC..  trans-72.4120.1-179.3-178.2-116.5000113Q649 V662 G670 G671 D672 L673 T674Q649-W667 HydrophobicContact CG-CE3 3.93Å; Q649-W667 HydrophobicContact CG-CZ3 4.26Å; V662-W667 PolarHBondContact O-N 2.94Å; W667-G670 VanDerWaalsContact CZ2-O 3.3Å; W667-G670 WeakPolarHBondContact CZ2-O 3.44Å; W667-G671 PolarHBondContact NE1-O 2.87Å; W667-D672 WeakPolarHBondContact CZ2-O 3.29Å; W667-L673 HydrophobicContact CB-CD1 3.85Å; W667-L673 HydrophobicContact CD2-CD1 4.38Å; W667-L673 HydrophobicContact CG-CD1 4.07Å; W667-T674 WeakPolarHBondContact CH2-OG1 3.37Å
668K92.6Very high93.1Very high135 Ų13538 Ų3859%0.58721%0.211SC*.  trans-123.2-6.8179.6-53-61.1172.7-162.10115.2Q649 H664 F665 I666 G670Q649-K668 VanDerWaalsContact CD-N 3.32Å; H664-K668 PolarHBondContact O-NZ 3.44Å; H664-K668 VanDerWaalsContact O-NZ 3.16Å; F665-K668 WeakPolarHBondContact O-CE 3.45Å; F665-K668 PolarHBondContact O-NZ 2.86Å; I666-K668 PolarHBondContact O-N 3.47Å; K668-G670 VanDerWaalsContact C-N 3.27Å; K668-G670 PolarHBondContact O-N 3.07Å
669S88.9Confident92.7Very high84 Ų8442.5 Ų42.559%0.58723%0.231SC*.SBendtrans-80.3-2-171.3-51.90000114.8Q649Q649-S669 PolarHBondContact NE2-OG 3.15Å
670G83.3Confident92Very high51 Ų5146 Ų4653%0.52625%0.246SC..SBendtrans73.5157-176.400000113.4W667 K668W667-G670 VanDerWaalsContact CZ2-O 3.3Å; W667-G670 WeakPolarHBondContact CZ2-O 3.44Å; K668-G670 VanDerWaalsContact C-N 3.27Å; K668-G670 PolarHBondContact O-N 3.07Å
671G90.4Very high90.6Very high61 Ų6151.1 Ų51.163%0.62928%0.284SS*.SBendtrans78.9-161.9-175.700000114.3W667W667-G671 PolarHBondContact NE1-O 2.87Å
672D92.8Very high88.3Confident38 Ų3861 Ų6120%0.20334%0.344CS..SBendtrans-62.8142.4179.6-71.2-6.2000110.9Y573 R589 W667 T674Y573-D672 HydrophobicContact CD2-CB 4.04Å; Y573-D672 HydrophobicContact CE2-CB 3.88Å; R589-D672 IonicContact CZ-OD2 2.96Å; R589-D672 VanDerWaalsContact CZ-OD2 3.29Å; R589-D672 IonicContact NE-OD2 3.28Å; R589-D672 PolarHBondContact NE-OD2 3.45Å; R589-D672 VanDerWaalsContact NE-OD2 3.09Å; R589-D672 IonicContact NH2-OD2 3.46Å; R589-D672 PolarHBondContact NH2-OD2 3.23Å; W667-D672 WeakPolarHBondContact CZ2-O 3.29Å; D672-T674 PolarHBondContact O-N 3.3Å; D672-T674 PolarHBondContact O-OG1 3.39Å
673L95.1Very high87.9Confident0 Ų064 Ų640%036%0.361CS..EExtended strand (participates in β ladder)trans-55.1134.5177.8170.765.8000109.2I570 F572 Y573 L659 V662 K663 W667 L675I570-L673 HydrophobicContact CG2-CB 4.5Å; F572-L673 CarbonylContact C-O 3.47Å; F572-L673 WeakPolarHBondContact CA-O 3.43Å; F572-L673 HydrophobicContact CB-CB 3.83Å; F572-L673 HydrophobicContact CB-CD2 4.15Å; F572-L673 HydrophobicContact CB-CG 4.08Å; F572-L673 VanDerWaalsContact CB-O 3.25Å; F572-L673 WeakPolarHBondContact CB-O 3.26Å; Y573-L673 PolarHBondContact N-O 3.12Å; L659-L673 HydrophobicContact CB-CD2 4.4Å; L659-L673 HydrophobicContact CD2-CD2 4.09Å; V662-L673 HydrophobicContact CG1-CD1 4.05Å; K663-L673 HydrophobicContact CB-CD1 4.41Å; K663-L673 HydrophobicContact CB-CD2 4.42Å; K663-L673 HydrophobicContact CD-CB 4.46Å; K663-L673 HydrophobicContact CG-CB 4.45Å; W667-L673 HydrophobicContact CB-CD1 3.85Å; W667-L673 HydrophobicContact CD2-CD1 4.38Å; W667-L673 HydrophobicContact CG-CD1 4.07Å; L673-L675 HydrophobicContact CD1-CD2 3.94Å; L673-L675 HydrophobicContact CD2-CD1 4.32Å; L673-L675 HydrophobicContact CD2-CD2 4.08Å; L673-L675 HydrophobicContact CD2-CG 4.24Å; L673-L675 HydrophobicContact CG-CD2 3.97Å; L673-L675 HydrophobicContact CG-CG 4.13Å
674T94.5Very high87.6Confident14 Ų1463.5 Ų63.59%0.08636%0.363CS..EExtended strand (participates in β ladder)trans-121.1121.4176-56.90000109.8W667 D672W667-T674 WeakPolarHBondContact CH2-OG1 3.37Å; D672-T674 PolarHBondContact O-N 3.3Å; D672-T674 PolarHBondContact O-OG1 3.39Å
675L94.9Very high87.2Confident0 Ų062.1 Ų62.10%036%0.361CS..EExtended strand (participates in β ladder)trans-109.9137180-57178.9000109.4F572 Y573 L574 Q575 V601 L646 M647 C648 L653 L659 V662 L673F572-L675 HydrophobicContact CD2-CD1 3.87Å; F572-L675 HydrophobicContact CD2-CG 4.35Å; F572-L675 HydrophobicContact CE2-CD1 4.11Å; Y573-L675 PolarHBondContact O-N 3.21Å; L574-L675 WeakPolarHBondContact CA-O 3.35Å; L574-L675 HydrophobicContact CD1-CB 4.01Å; Q575-L675 PolarHBondContact N-O 3.1Å; V601-L675 HydrophobicContact CG1-CD1 4.35Å; L646-L675 HydrophobicContact CD1-CB 4.42Å; L646-L675 HydrophobicContact CD2-CB 4.48Å; L646-L675 HydrophobicContact CD2-CD1 3.91Å; L646-L675 HydrophobicContact CG-CB 4.39Å; M647-L675 CarbonylContact O-C 3.59Å; M647-L675 WeakPolarHBondContact O-CA 3.3Å; C648-L675 HydrophobicContact CB-CD2 4.07Å; L653-L675 HydrophobicContact CD1-CD2 3.81Å; L659-L675 HydrophobicContact CD2-CD1 3.77Å; V662-L675 HydrophobicContact CG1-CD2 4.14Å; L673-L675 HydrophobicContact CD1-CD2 3.94Å; L673-L675 HydrophobicContact CD2-CD1 4.32Å; L673-L675 HydrophobicContact CD2-CD2 4.08Å; L673-L675 HydrophobicContact CD2-CG 4.24Å; L673-L675 HydrophobicContact CG-CD2 3.97Å; L673-L675 HydrophobicContact CG-CG 4.13Å
676H92.8Very high86.8Confident43 Ų4362.9 Ų62.920%0.19937%0.37CS..EExtended strand (participates in β ladder)trans-109.7137175.9-59.887.9000109.9Q575 H577 L646 M647Q575-H676 CarbonylContact O-C 3.51Å; Q575-H676 WeakPolarHBondContact O-CA 3.4Å; H577-H676 HydrophobicContact CB-CB 4.15Å; L646-H676 CarbonylContact C-O 3.6Å; L646-H676 WeakPolarHBondContact CA-O 3.26Å; M647-H676 HydrophobicContact CB-CB 4.35Å; M647-H676 PolarHBondContact N-O 2.78Å; M647-H676 PolarHBondContact O-N 2.91Å
677Y91.1Very high86.3Confident17 Ų1766.3 Ų66.37%0.06739%0.39CS..EExtended strand (participates in β ladder)trans-116148.517563.4-93.1000111.7L574 Q575 P576 H577 V605 I609 E645L574-Y677 HydrophobicContact CD1-CD1 3.77Å; L574-Y677 HydrophobicContact CD1-CE1 4.48Å; L574-Y677 HydrophobicContact CD2-CD1 4.5Å; L574-Y677 HydrophobicContact CG-CD1 3.75Å; L574-Y677 HydrophobicContact CG-CE1 3.98Å; Q575-Y677 WeakPolarHBondContact O-CD1 3.33Å; Q575-Y677 WeakPolarHBondContact O-CE1 3.32Å; Q575-Y677 PolarHBondContact O-N 3.13Å; P576-Y677 HydrophobicContact CB-CE2 4.14Å; H577-Y677 PolarHBondContact N-O 2.64Å; V605-Y677 HydrophobicContact CG1-CD1 4.42Å; V605-Y677 HydrophobicContact CG1-CD2 3.57Å; V605-Y677 HydrophobicContact CG1-CE2 4.21Å; V605-Y677 HydrophobicContact CG1-CG 3.71Å; V605-Y677 HydrophobicContact CG2-CD1 4.04Å; V605-Y677 HydrophobicContact CG2-CG 3.95Å; I609-Y677 HydrophobicContact CD1-CE1 3.93Å; I609-Y677 HydrophobicContact CG2-CE2 3.85Å; I609-Y677 WeakPolarHBondContact CG2-OH 3.48Å; E645-Y677 VanDerWaalsContact O-CA 3.32Å; E645-Y677 WeakPolarHBondContact O-CA 3.43Å
678R88.4Confident85.6Confident68 Ų6868.5 Ų68.526%0.25741%0.408SS..EExtended strand (participates in β ladder)trans-146.3158.416767.1-178-174-175.21.5110.6H577 S579 E645H577-R678 HydrophobicContact CB-CB 4.04Å; S579-R678 WeakPolarHBondContact OG-CD 3.34Å; S579-R678 PolarHBondContact OG-NH1 3.28Å; E645-R678 HydrophobicContact CB-CG 3.96Å; E645-R678 PolarHBondContact N-O 3.11Å; E645-R678 PolarHBondContact O-N 2.92Å; E645-R678 IonicContact OE2-CZ 3.15Å; E645-R678 IonicContact OE2-NE 3.6Å; E645-R678 PolarHBondContact OE2-NE 2.61Å; E645-R678 IonicContact OE2-NH2 2.71Å; E645-R678 PolarHBondContact OE2-NH2 2.65Å
679Q85.8Confident85.1Confident112 Ų11263.7 Ų63.752%0.52340%0.395SS..EExtended strand (participates in β ladder)trans-76.6136.3169.6-165171.6-6.300109.3I610 K643I610-Q679 HydrophobicContact CD1-CB 4.35Å; K643-Q679 CarbonylContact O-C 3.57Å; K643-Q679 WeakPolarHBondContact O-CA 3.38Å; K643-Q679 WeakPolarHBondContact O-CG 3.39Å
680K82.2Confident84.9Confident74 Ų7462.2 Ų62.232%0.32238%0.38SS..  trans-63.3135.2172.4-75.6-179.4178.7170.10109E641 E642 K643 I644 E645 T682E641-K680 PolarHBondContact O-NZ 3.08Å; E642-K680 VanDerWaalsContact O-CD 3.28Å; E642-K680 WeakPolarHBondContact O-CD 3.46Å; K643-K680 PolarHBondContact O-N 3.11Å; I644-K680 WeakPolarHBondContact O-CE 3.49Å; E645-K680 HydrophobicContact CB-CG 4.4Å; E645-K680 HydrophobicContact CG-CD 4.02Å; E645-K680 HydrophobicContact CG-CG 3.53Å; K680-T682 PolarHBondContact O-N 3.37Å
681S63.8Low85Confident120 Ų12063.1 Ų63.184%0.83937%0.368SS*.  trans-68.1115.2170-37.40000107.3
682T48.3Very low84.5Confident210 Ų21063.3 Ų63.3100%1.28834%0.344SS*.  trans-63.10168.544.50000111.4K680K680-T682 PolarHBondContact O-N 3.37Å

Retrieved 682 of 682 residues in 1636.1 ms (Link to these results)