A0A087YCA6_POEFO Loading...

triacylglycerol lipase

AlphaFold DB , UniProt , Accession A0A087YCA6, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 496 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M42Very low40.8Very low229 Ų229124.5 Ų124.5100%1.12860%0.596SS**  0110.50-148158.871.800106.6L3M1-L3 PolarHBondContact O-N 3.48Å
2N38.6Very low41.2Very low112 Ų112119.7 Ų119.760%0.59958%0.576SS**  trans-66.6125.3-165.8-102.2-37.5000111.4K4 I5 F6N2-K4 PolarHBondContact O-N 3.38Å; N2-I5 HydrophobicContact CB-CB 4.46Å; N2-I5 HydrophobicContact CB-CD1 3.92Å; N2-I5 HydrophobicContact CB-CG1 3.93Å; N2-I5 WeakPolarHBondContact O-CB 3.37Å; N2-I5 PolarHBondContact O-N 3.28Å; N2-F6 PolarHBondContact O-N 3.12Å
3L34.3Very low41.1Very low134 Ų134118.7 Ų118.770%0.70257%0.57SS**Hα-helixtrans-52.7-29.6175.7-164.571.7000112.2M1 F6 L7M1-L3 PolarHBondContact O-N 3.48Å; L3-F6 PolarHBondContact O-N 3Å; L3-L7 WeakPolarHBondContact O-CG 3.12Å; L3-L7 PolarHBondContact O-N 3.09Å; L3-L7 VanDerWaalsContact O-N 3.07Å
4K36.9Very low41.2Very low172 Ų172122.8 Ų122.875%0.74858%0.578SS**Hα-helixtrans-65.2-34.9173.4-68.2-177.3175.4-176.20114.2N2 L8N2-K4 PolarHBondContact O-N 3.38Å; K4-L8 WeakPolarHBondContact O-CB 3.44Å; K4-L8 PolarHBondContact O-N 3.27Å; K4-L8 VanDerWaalsContact O-N 3.15Å
5I39.7Very low41.2Very low100 Ų100117.6 Ų117.651%0.51356%0.558SS.*Hα-helixtrans-73.5-36.8177.4-63.8174.9000109.8N2 L8 W9N2-I5 HydrophobicContact CB-CB 4.46Å; N2-I5 HydrophobicContact CB-CD1 3.92Å; N2-I5 HydrophobicContact CB-CG1 3.93Å; N2-I5 WeakPolarHBondContact O-CB 3.37Å; N2-I5 PolarHBondContact O-N 3.28Å; I5-L8 PolarHBondContact O-N 2.86Å; I5-W9 WeakPolarHBondContact O-CB 3.24Å; I5-W9 PolarHBondContact O-N 2.66Å
6F37.6Very low40.9Very low135 Ų135115.6 Ų115.659%0.59256%0.56SS**Hα-helixtrans-65.5-44176.3-162.1-99.3000111.5N2 L3 L8 W9 T10N2-F6 PolarHBondContact O-N 3.12Å; L3-F6 PolarHBondContact O-N 3Å; F6-L8 VanDerWaalsContact C-N 3.33Å; F6-L8 PolarHBondContact O-N 3.13Å; F6-W9 PolarHBondContact O-N 3.29Å; F6-T10 HydrophobicContact CD1-CG2 4.31Å; F6-T10 HydrophobicContact CE1-CG2 4.15Å; F6-T10 PolarHBondContact O-N 3.02Å; F6-T10 PolarHBondContact O-OG1 3.2Å
7L44.5Very low40.5Very low95 Ų95112.9 Ų112.950%0.49756%0.556SS.*Hα-helixtrans-63.7-35.8176-73.2165.4000113.1L3 T10 F11L3-L7 WeakPolarHBondContact O-CG 3.12Å; L3-L7 PolarHBondContact O-N 3.09Å; L3-L7 VanDerWaalsContact O-N 3.07Å; L7-T10 VanDerWaalsContact C-OG1 3.31Å; L7-T10 VanDerWaalsContact CA-OG1 3.24Å; L7-T10 WeakPolarHBondContact CA-OG1 3.4Å; L7-T10 PolarHBondContact O-OG1 2.73Å; L7-F11 WeakPolarHBondContact O-CB 2.95Å; L7-F11 PolarHBondContact O-N 2.83Å
8L44.2Very low40.3Very low68 Ų68110.7 Ų110.736%0.35656%0.559SS.*Hα-helixtrans-68.4-39.6174.3-165.673.8000111.6K4 I5 F6 F11 L12 F260K4-L8 WeakPolarHBondContact O-CB 3.44Å; K4-L8 PolarHBondContact O-N 3.27Å; K4-L8 VanDerWaalsContact O-N 3.15Å; I5-L8 PolarHBondContact O-N 2.86Å; F6-L8 VanDerWaalsContact C-N 3.33Å; F6-L8 PolarHBondContact O-N 3.13Å; L8-F11 PolarHBondContact O-N 3.22Å; L8-L12 HydrophobicContact CG-CD1 4.1Å; L8-L12 WeakPolarHBondContact O-CB 3.4Å; L8-L12 WeakPolarHBondContact O-CD1 3.27Å; L8-L12 VanDerWaalsContact O-CG 3.29Å; L8-L12 WeakPolarHBondContact O-CG 3.47Å; L8-L12 PolarHBondContact O-N 2.98Å; L8-F260 HydrophobicContact CD1-CD1 4.42Å
9W38Very low40.3Very low160 Ų160111.8 Ų111.861%0.60657%0.566SS**Hα-helixtrans-66.4-41176-127.374.5000111.7I5 F6 L12 Q13I5-W9 WeakPolarHBondContact O-CB 3.24Å; I5-W9 PolarHBondContact O-N 2.66Å; F6-W9 PolarHBondContact O-N 3.29Å; W9-L12 PolarHBondContact O-N 2.89Å; W9-Q13 HydrophobicContact CE3-CG 4.06Å; W9-Q13 VanDerWaalsContact CZ3-CD 3.46Å; W9-Q13 HydrophobicContact CZ3-CG 4.21Å; W9-Q13 WeakPolarHBondContact O-CB 3.42Å; W9-Q13 WeakPolarHBondContact O-CG 3.15Å; W9-Q13 PolarHBondContact O-N 3.08Å
10T44.2Very low39.8Very low55 Ų55109.5 Ų109.534%0.33757%0.571SS.*Hα-helixtrans-66.1-39.3173.850.20000111.7F6 L7 Q13 Y14F6-T10 HydrophobicContact CD1-CG2 4.31Å; F6-T10 HydrophobicContact CE1-CG2 4.15Å; F6-T10 PolarHBondContact O-N 3.02Å; F6-T10 PolarHBondContact O-OG1 3.2Å; L7-T10 VanDerWaalsContact C-OG1 3.31Å; L7-T10 VanDerWaalsContact CA-OG1 3.24Å; L7-T10 WeakPolarHBondContact CA-OG1 3.4Å; L7-T10 PolarHBondContact O-OG1 2.73Å; T10-Q13 PolarHBondContact O-N 2.74Å; T10-Y14 WeakPolarHBondContact O-CB 3.17Å; T10-Y14 PolarHBondContact O-N 2.77Å
11F49.4Very low39.2Very low109 Ų109112.1 Ų112.148%0.47858%0.581SS.*Hα-helixtrans-62-46.5174.6-178.3-98.4000111.5L7 L8 Y14 V15L7-F11 WeakPolarHBondContact O-CB 2.95Å; L7-F11 PolarHBondContact O-N 2.83Å; L8-F11 PolarHBondContact O-N 3.22Å; F11-Y14 PolarHBondContact O-N 3.27Å; F11-V15 HydrophobicContact CD1-CG2 4.39Å; F11-V15 HydrophobicContact CE1-CG2 4.13Å; F11-V15 HydrophobicContact CE2-CG2 4.29Å; F11-V15 HydrophobicContact CZ-CG2 4.07Å; F11-V15 WeakPolarHBondContact O-CB 3.5Å; F11-V15 VanDerWaalsContact O-CG2 3.23Å; F11-V15 WeakPolarHBondContact O-CG2 3.41Å; F11-V15 PolarHBondContact O-N 3.01Å
12L45.5Very low38.8Very low67 Ų67109 Ų10935%0.35157%0.569SS.*Hα-helixtrans-65.6-39.7178.8-76.9161.3000113.1L8 W9 S16 L222L8-L12 HydrophobicContact CG-CD1 4.1Å; L8-L12 WeakPolarHBondContact O-CB 3.4Å; L8-L12 WeakPolarHBondContact O-CD1 3.27Å; L8-L12 VanDerWaalsContact O-CG 3.29Å; L8-L12 WeakPolarHBondContact O-CG 3.47Å; L8-L12 PolarHBondContact O-N 2.98Å; W9-L12 PolarHBondContact O-N 2.89Å; L12-S16 WeakPolarHBondContact O-CB 3.21Å; L12-S16 PolarHBondContact O-N 3.05Å; L12-S16 PolarHBondContact O-OG 2.83Å; L12-L222 HydrophobicContact CD2-CD1 3.6Å
13Q39.9Very low38.3Very low107 Ų107107 Ų10750%0.557%0.574SS.*Hα-helixtrans-67.5-42.4174.7-78.3-171.2-47.600111.9W9 T10 S16 S17W9-Q13 HydrophobicContact CE3-CG 4.06Å; W9-Q13 VanDerWaalsContact CZ3-CD 3.46Å; W9-Q13 HydrophobicContact CZ3-CG 4.21Å; W9-Q13 WeakPolarHBondContact O-CB 3.42Å; W9-Q13 WeakPolarHBondContact O-CG 3.15Å; W9-Q13 PolarHBondContact O-N 3.08Å; T10-Q13 PolarHBondContact O-N 2.74Å; Q13-S16 PolarHBondContact O-N 3.03Å; Q13-S17 WeakPolarHBondContact O-CB 3.33Å; Q13-S17 PolarHBondContact O-N 3.13Å; Q13-S17 PolarHBondContact O-OG 3.07Å
14Y42.1Very low37.9Very low176 Ų176106.2 Ų106.269%0.6958%0.575SS**Hα-helixtrans-67.8-41-179-123.6-94.1000112.8T10 F11 S16 S17 A18T10-Y14 WeakPolarHBondContact O-CB 3.17Å; T10-Y14 PolarHBondContact O-N 2.77Å; F11-Y14 PolarHBondContact O-N 3.27Å; Y14-S16 VanDerWaalsContact C-N 3.32Å; Y14-S16 PolarHBondContact O-N 2.99Å; Y14-S17 VanDerWaalsContact CA-OG 3.32Å; Y14-S17 WeakPolarHBondContact CA-OG 3.06Å; Y14-S17 PolarHBondContact O-N 3.34Å; Y14-S17 PolarHBondContact O-OG 2.9Å; Y14-A18 VanDerWaalsContact O-CB 3.32Å; Y14-A18 WeakPolarHBondContact O-CB 3.38Å; Y14-A18 PolarHBondContact O-N 3.1Å
15V41.7Very low37.7Very low45 Ų45105.4 Ų105.427%0.27358%0.578SS.*Hα-helixtrans-64.5-39.2176.2172.40000110.6F11 L19 V224F11-V15 HydrophobicContact CD1-CG2 4.39Å; F11-V15 HydrophobicContact CE1-CG2 4.13Å; F11-V15 HydrophobicContact CE2-CG2 4.29Å; F11-V15 HydrophobicContact CZ-CG2 4.07Å; F11-V15 WeakPolarHBondContact O-CB 3.5Å; F11-V15 VanDerWaalsContact O-CG2 3.23Å; F11-V15 WeakPolarHBondContact O-CG2 3.41Å; F11-V15 PolarHBondContact O-N 3.01Å; V15-L19 HydrophobicContact CG1-CD1 4.36Å; V15-L19 PolarHBondContact O-N 3.3Å; V15-V224 HydrophobicContact CG1-CG2 3.71Å
16S36Very low37Very low85 Ų85109.3 Ų109.359%0.59459%0.591SS**Hα-helixtrans-71.6-34.8177.6-61.90000112.7L12 Q13 Y14L12-S16 WeakPolarHBondContact O-CB 3.21Å; L12-S16 PolarHBondContact O-N 3.05Å; L12-S16 PolarHBondContact O-OG 2.83Å; Q13-S16 PolarHBondContact O-N 3.03Å; Y14-S16 VanDerWaalsContact C-N 3.32Å; Y14-S16 PolarHBondContact O-N 2.99Å
17S34.7Very low36.8Very low70 Ų70106.5 Ų106.549%0.4960%0.601SS.*Hα-helixtrans-76.6-32.6177.754.10000113.1Q13 Y14 L19 G20Q13-S17 WeakPolarHBondContact O-CB 3.33Å; Q13-S17 PolarHBondContact O-N 3.13Å; Q13-S17 PolarHBondContact O-OG 3.07Å; Y14-S17 VanDerWaalsContact CA-OG 3.32Å; Y14-S17 WeakPolarHBondContact CA-OG 3.06Å; Y14-S17 PolarHBondContact O-N 3.34Å; Y14-S17 PolarHBondContact O-OG 2.9Å; S17-L19 PolarHBondContact O-N 3.2Å; S17-G20 PolarHBondContact O-N 3.12Å
18A36.5Very low35.9Very low74 Ų74109.3 Ų109.361%0.61261%0.611SS**Hα-helixtrans-68.6-23.1175.700000113.2Y14Y14-A18 VanDerWaalsContact O-CB 3.32Å; Y14-A18 WeakPolarHBondContact O-CB 3.38Å; Y14-A18 PolarHBondContact O-N 3.1Å
19L39.8Very low35.4Very low132 Ų132114.5 Ų114.569%0.69164%0.639SS**THydrogen-bonded Turntrans-88.7-9175.1-89.2149.7000113.4V15 S17 V224V15-L19 HydrophobicContact CG1-CD1 4.36Å; V15-L19 PolarHBondContact O-N 3.3Å; S17-L19 PolarHBondContact O-N 3.2Å; L19-V224 HydrophobicContact CD1-CG2 4.4Å
20G29.6Very low35Very low65 Ų65114.9 Ų114.967%0.6765%0.648SS**THydrogen-bonded Turntrans-87.8-17.3-177.900000114.9S17S17-G20 PolarHBondContact O-N 3.12Å
21E27.9Very low34.4Very low165 Ų165116 Ų11677%0.77167%0.67SS**SBendtrans-114.5119.7174.3-76.6-175.8152.900109.4G23E21-G23 PolarHBondContact O-N 2.02Å
22N34.8Very low33.8Very low164 Ų164118.1 Ų118.188%0.87768%0.679SS**  trans-60.581.6158.7-81.1-33.9000108.2V24N22-V24 PolarHBondContact O-N 3.36Å
23G27.4Very low33.1Very low69 Ų69122.3 Ų122.371%0.71170%0.697SS**  trans-69.482.5166.100000108.2E21 L25E21-G23 PolarHBondContact O-N 2.02Å; G23-L25 PolarHBondContact O-N 3.13Å; G23-L25 VanDerWaalsContact O-N 3.09Å
24V25.6Very low33Very low118 Ų118121.3 Ų121.372%0.71570%0.702SS**  trans-49.6115.9161.5172.20000106.7N22 K26N22-V24 PolarHBondContact O-N 3.36Å; V24-K26 PolarHBondContact O-N 3.24Å
25L32.5Very low32.7Very low154 Ų154117.7 Ų117.781%0.80670%0.698SS**  trans-56.998.3160-76.3167.4000106.1G23 G27G23-L25 PolarHBondContact O-N 3.13Å; G23-L25 VanDerWaalsContact O-N 3.09Å; L25-G27 PolarHBondContact O-N 3.36Å; L25-G27 VanDerWaalsContact O-N 3.14Å
26K25Very low32.9Very low182 Ų182120 Ų12079%0.79171%0.709SS**  trans-64.3113.1165.3-92.9-176.4171.7-175.40106.1V24 E28V24-K26 PolarHBondContact O-N 3.24Å; K26-E28 PolarHBondContact O-N 2.97Å
27G34.4Very low33.3Very low77 Ų77118.5 Ų118.579%0.79470%0.697SS**  trans-64.4115.3165.600000108.6L25L25-G27 PolarHBondContact O-N 3.36Å; L25-G27 VanDerWaalsContact O-N 3.14Å
28E25.8Very low33.8Very low154 Ų154122.8 Ų122.872%0.7271%0.709SS**  trans-123.2112.1155.8-76.4178.8170.500106K26 E30K26-E28 PolarHBondContact O-N 2.97Å; E28-E30 PolarHBondContact O-N 3.44Å
29D33.3Very low34.6Very low177 Ų177122.1 Ų122.195%0.94770%0.703SS**  trans-60.389.6161.2-91.2-37.9000107.4
30E29.5Very low35.7Very low167 Ų167116.3 Ų116.378%0.7867%0.673SS**  trans-127.2124.7161.6-69.8-160.8166.300108.5E28 F32E28-E30 PolarHBondContact O-N 3.44Å; E30-F32 PolarHBondContact O-N 3.32Å
31G31.9Very low37.2Very low78 Ų78120.4 Ų120.480%0.80467%0.674SS**  trans-54.1126.7-177.900000110.9E33G31-E33 VanDerWaalsContact C-N 3.3Å; G31-E33 PolarHBondContact O-N 2.84Å
32F35Very low39.3Very low155 Ų155115.7 Ų115.768%0.6867%0.67SS**  trans-68.490175.5-168.3-100.4000109.1E30 D36E30-F32 PolarHBondContact O-N 3.32Å; F32-D36 HydrophobicContact CE1-CB 4.49Å; F32-D36 HydrophobicContact CZ-CB 3.87Å
33E31.5Very low41.7Very low155 Ų155112.9 Ų112.972%0.72465%0.647SS**  trans-68.4149.1173.2-113.3178.717200110.9G31 T35G31-E33 VanDerWaalsContact C-N 3.3Å; G31-E33 PolarHBondContact O-N 2.84Å; E33-T35 PolarHBondContact O-N 2.95Å; E33-T35 PolarHBondContact O-OG1 3.13Å
34S38.1Very low45Very low86 Ų86110.3 Ų110.360%0.60162%0.617SS**THydrogen-bonded Turntrans-50.48.4-169.947.10000120.3T37S34-T37 PolarHBondContact O-OG1 2.85Å
35T35Very low48.3Very low100 Ų100109.7 Ų109.761%0.61361%0.605SS**THydrogen-bonded Turntrans-80-32-165.944.20000114.9E33E33-T35 PolarHBondContact O-N 2.95Å; E33-T35 PolarHBondContact O-OG1 3.13Å
36D46.1Very low51.4Low92 Ų92102.7 Ų102.749%0.49257%0.568SS.*THydrogen-bonded Turntrans-78.3-23.3-180-83.8-23.4000114F32 E38 A39F32-D36 HydrophobicContact CE1-CB 4.49Å; F32-D36 HydrophobicContact CZ-CB 3.87Å; D36-E38 VanDerWaalsContact C-N 3.27Å; D36-E38 PolarHBondContact O-N 3.18Å; D36-A39 PolarHBondContact O-N 3Å
37T45.9Very low54.7Low55 Ų5595 Ų9534%0.33754%0.535SS..THydrogen-bonded Turntrans-68.8-23177.431.80000113.7S34S34-T37 PolarHBondContact O-OG1 2.85Å
38E44.7Very low57.6Low160 Ų16092 Ų9275%0.74850%0.5SS*.THydrogen-bonded Turntrans-76.1-28.8174.4-71.8-170.7155.600112.3D36 V40 H41D36-E38 VanDerWaalsContact C-N 3.27Å; D36-E38 PolarHBondContact O-N 3.18Å; E38-V40 PolarHBondContact O-N 3.31Å; E38-H41 PolarHBondContact O-N 3.22Å
39A53.3Low60.8Low60 Ų6085.4 Ų85.450%0.49647%0.469SS..THydrogen-bonded Turntrans-70.8-15.5-177.800000114.5D36 R43D36-A39 PolarHBondContact O-N 3Å; A39-R43 VanDerWaalsContact O-CD 3.27Å; A39-R43 WeakPolarHBondContact O-CD 3.43Å
40V62.3Low63.4Low10 Ų1082.8 Ų82.86%0.06145%0.449CS..THydrogen-bonded Turntrans-101.1-17.8-178.8176.50000112.5E38 G42 R43 I44 L121 A135E38-V40 PolarHBondContact O-N 3.31Å; V40-G42 PolarHBondContact O-N 3.11Å; V40-R43 WeakPolarHBondContact O-CB 3.34Å; V40-R43 PolarHBondContact O-N 2.83Å; V40-I44 HydrophobicContact CG1-CD1 3.32Å; V40-I44 HydrophobicContact CG1-CG1 3.99Å; V40-L121 HydrophobicContact CG1-CD1 4.03Å; V40-L121 HydrophobicContact CG2-CD1 4.25Å; V40-A135 HydrophobicContact CG2-CB 3.69Å
41H62.1Low66Low150 Ų15076.4 Ų76.469%0.69442%0.423SS*.THydrogen-bonded Turntrans-58.9122.2-173.6-165.766.6000111.8E38 R43E38-H41 PolarHBondContact O-N 3.22Å; H41-R43 VanDerWaalsContact C-N 3.32Å; H41-R43 PolarHBondContact O-N 3.42Å
42G70.2Confident68.3Low66 Ų6676.9 Ų76.968%0.6841%0.407SS*.THydrogen-bonded Turntrans79.51.7-179.900000116V40V40-G42 PolarHBondContact O-N 3.11Å
43R87Confident70.3Confident105 Ų10572.8 Ų72.840%0.39639%0.392SS..THydrogen-bonded Turntrans-92.9-15.6177.3-57.6-174.977.2-178.20.8113.7A39 V40 H41A39-R43 VanDerWaalsContact O-CD 3.27Å; A39-R43 WeakPolarHBondContact O-CD 3.43Å; V40-R43 WeakPolarHBondContact O-CB 3.34Å; V40-R43 PolarHBondContact O-N 2.83Å; H41-R43 VanDerWaalsContact C-N 3.32Å; H41-R43 PolarHBondContact O-N 3.42Å
44I95.6Very high72.1Confident15 Ų1566.6 Ų66.68%0.07736%0.364CS..  trans-102.4132.4176.2-57.4164.2000108.6V40 Y46 V116 D117 W118 L121 V136 D139V40-I44 HydrophobicContact CG1-CD1 3.32Å; V40-I44 HydrophobicContact CG1-CG1 3.99Å; I44-Y46 HydrophobicContact CG2-CE1 4.41Å; I44-Y46 HydrophobicContact CG2-CE2 3.9Å; I44-V116 HydrophobicContact CG2-CG1 3.82Å; I44-D117 CarbonylContact C-O 3.58Å; I44-D117 WeakPolarHBondContact CA-O 3.41Å; I44-W118 HydrophobicContact CG1-CB 4.24Å; I44-L121 HydrophobicContact CG1-CD1 4.26Å; I44-V136 HydrophobicContact CD1-CB 4.09Å; I44-V136 HydrophobicContact CD1-CG1 3.9Å; I44-V136 HydrophobicContact CD1-CG2 3.98Å; I44-V136 HydrophobicContact CG1-CG1 4.49Å; I44-V136 HydrophobicContact CG1-CG2 4.48Å; I44-D139 HydrophobicContact CD1-CB 3.55Å
45K95.4Very high73.8Confident105 Ų10569.2 Ų69.246%0.45737%0.371SS..EExtended strand (participates in β ladder)trans-119.3136.7177.6-55.6175.1-177.5172.90110.6Y60 D117K45-Y60 HydrophobicContact CB-CD1 4.04Å; K45-Y60 HydrophobicContact CB-CE1 3.99Å; K45-Y60 HydrophobicContact CD-CE1 4.17Å; K45-D117 HydrophobicContact CB-CB 4.17Å; K45-D117 PolarHBondContact N-O 2.87Å; K45-D117 PolarHBondContact O-N 2.72Å
46Y96.6Very high75.8Confident8 Ų869.2 Ų69.23%0.03136%0.364CS..EExtended strand (participates in β ladder)trans-107.589.1-179.5-62.2-87.7000109.9I44 M48 Y60 L61 F82 V114 V116 D139 I140 M143I44-Y46 HydrophobicContact CG2-CE1 4.41Å; I44-Y46 HydrophobicContact CG2-CE2 3.9Å; Y46-M48 PolarHBondContact O-N 3.33Å; Y46-Y60 CarbonylContact O-C 3.48Å; Y46-Y60 WeakPolarHBondContact O-CA 3.33Å; Y46-L61 PolarHBondContact O-N 2.83Å; Y46-F82 HydrophobicContact CD1-CD2 4.35Å; Y46-F82 AromaticContact CD1-CE2 3.64Å; Y46-F82 HydrophobicContact CD1-CE2 3.64Å; Y46-F82 HydrophobicContact CD1-CZ 4.4Å; Y46-F82 HydrophobicContact CE1-CD2 4.49Å; Y46-F82 AromaticContact CE1-CE2 3.88Å; Y46-F82 HydrophobicContact CE1-CE2 3.88Å; Y46-V114 HydrophobicContact CD1-CG1 4.44Å; Y46-V116 HydrophobicContact CD1-CG2 4.15Å; Y46-V116 HydrophobicContact CE1-CG1 4.25Å; Y46-V116 HydrophobicContact CE1-CG2 4.25Å; Y46-D139 WeakPolarHBondContact CE2-OD1 3.42Å; Y46-D139 VanDerWaalsContact OH-C 3.31Å; Y46-D139 PolarHBondContact OH-O 2.96Å; Y46-D139 PolarHBondContact OH-OD1 2.87Å; Y46-I140 HydrophobicContact CE1-CG1 4Å; Y46-I140 WeakPolarHBondContact OH-CA 3.34Å; Y46-I140 PolarHBondContact OH-N 2.79Å; Y46-M143 HydrophobicContact CD1-CE 4.14Å; Y46-M143 HydrophobicContact CD1-CG 4.34Å; Y46-M143 HydrophobicContact CD2-CE 3.26Å; Y46-M143 HydrophobicContact CE1-CB 4.22Å; Y46-M143 HydrophobicContact CE1-CE 4.4Å; Y46-M143 HydrophobicContact CE1-CG 4.18Å; Y46-M143 HydrophobicContact CE2-CE 3.61Å; Y46-M143 HydrophobicContact CG-CE 3.56Å
47N95.1Very high77.2Confident20 Ų2072.7 Ų72.711%0.10738%0.377CS..EExtended strand (participates in β ladder)trans-88.296.6-175.2-175.4-2.9000110.9R49 G58 C59 Y60 V114 V115N47-R49 PolarHBondContact ND2-NH1 2.87Å; N47-R49 PolarHBondContact O-N 3.28Å; N47-G58 WeakPolarHBondContact OD1-CA 3.44Å; N47-C59 CarbonylContact C-O 3.51Å; N47-Y60 HydrophobicContact CB-CD1 4.2Å; N47-Y60 HydrophobicContact CB-CE1 3.85Å; N47-V114 WeakPolarHBondContact O-CA 3.48Å; N47-V115 HydrophobicContact CB-CB 4.41Å; N47-V115 PolarHBondContact N-O 2.99Å; N47-V115 PolarHBondContact O-N 3.36Å
48M95.7Very high79Confident13 Ų1370.7 Ų70.76%0.06437%0.368CS..EExtended strand (participates in β ladder)trans-71.6118.1170.8-174.2175.6167.400110.3Y46 G58 C59 L61 C72 F74 N112 V113 V114Y46-M48 PolarHBondContact O-N 3.33Å; M48-G58 WeakPolarHBondContact O-CA 3.06Å; M48-C59 WeakPolarHBondContact CA-O 3.44Å; M48-C59 WeakPolarHBondContact CB-O 3.43Å; M48-C59 PolarHBondContact N-O 3.02Å; M48-C59 PolarHBondContact O-N 2.89Å; M48-L61 HydrophobicContact CB-CD1 4.46Å; M48-L61 HydrophobicContact CB-CD2 4.38Å; M48-L61 HydrophobicContact CB-CG 4.22Å; M48-L61 HydrophobicContact SD-CD2 4.28Å; M48-C72 HydrophobicContact SD-CB 3.79Å; M48-F74 HydrophobicContact SD-CB 4.28Å; M48-F74 HydrophobicContact SD-CD2 4.01Å; M48-N112 HydrophobicContact CE-CB 3.94Å; M48-N112 VanDerWaalsContact CE-OD1 3.32Å; M48-N112 WeakPolarHBondContact CE-OD1 3.4Å; M48-N112 HydrophobicContact SD-CB 4.43Å; M48-V113 WeakPolarHBondContact CA-O 3.34Å; M48-V114 HydrophobicContact CB-CG2 4.15Å; M48-V114 HydrophobicContact CG-CG2 4.28Å
49R93.5Very high81.2Confident16 Ų1663.8 Ų63.86%0.0634%0.337CS..  trans-80.8126.8-172.4-59.3-59.2-49.316416.4110.8N47 S51 D53 L54 Q56 V101 M105 V113 V115N47-R49 PolarHBondContact ND2-NH1 2.87Å; N47-R49 PolarHBondContact O-N 3.28Å; R49-S51 PolarHBondContact NH2-O 3.32Å; R49-D53 PolarHBondContact NH2-O 2.7Å; R49-L54 VanDerWaalsContact NE-CD2 3.32Å; R49-L54 PolarHBondContact NH1-O 3.4Å; R49-L54 VanDerWaalsContact NH2-CA 3.3Å; R49-Q56 PolarHBondContact NH1-O 2.92Å; R49-Q56 VanDerWaalsContact NH1-O 3.11Å; R49-Q56 PolarHBondContact NH2-O 3.25Å; R49-V101 HydrophobicContact CB-CG1 4.41Å; R49-V101 HydrophobicContact CG-CG1 3.86Å; R49-M105 HydrophobicContact CB-CE 4.1Å; R49-M105 HydrophobicContact CB-SD 3.65Å; R49-V113 PolarHBondContact N-O 3.42Å; R49-V115 HydrophobicContact CG-CG2 3.96Å
50K86.4Confident83.2Confident123 Ų12364.6 Ų64.654%0.53533%0.328SS..  trans-103.9-16.4174.6-66.8-174.3171.3178.50113.8C59 E71 C72K50-C59 HydrophobicContact CD-CB 4.31Å; K50-E71 PolarHBondContact NZ-O 2.82Å; K50-C72 WeakPolarHBondContact CE-O 3.24Å
51S84.5Confident84.8Confident33 Ų3364.2 Ų64.223%0.23133%0.326CS..SBendtrans-138.1149.6-175.3-177.90000110.3R49 D53 Q56R49-S51 PolarHBondContact NH2-O 3.32Å; S51-D53 PolarHBondContact O-N 3.48Å; S51-D53 PolarHBondContact OG-N 3.41Å; S51-Q56 PolarHBondContact OG-OE1 3.32Å
52L80.3Confident86.2Confident87 Ų8761.1 Ų61.146%0.45531%0.312SS..SBendtrans-67.4-21.7172.6-65.9175.7000112.1L54 M105 Q106L52-L54 PolarHBondContact O-N 3.46Å; L52-M105 HydrophobicContact CD2-CB 3.64Å; L52-M105 HydrophobicContact CD2-SD 4.19Å; L52-Q106 HydrophobicContact CD1-CG 4.3Å; L52-Q106 HydrophobicContact CD2-CG 4.11Å
53D76.2Confident87.3Confident69 Ų6960.7 Ų60.737%0.36930%0.296SS..  trans-79.2110.3173.5-177.20.4000109.6R49 S51 D55 Q56R49-D53 PolarHBondContact NH2-O 2.7Å; S51-D53 PolarHBondContact O-N 3.48Å; S51-D53 PolarHBondContact OG-N 3.41Å; D53-D55 PolarHBondContact O-N 3.21Å; D53-D55 WeakPolarHBondContact OD1-CB 3.29Å; D53-D55 PolarHBondContact OD1-N 3.42Å; D53-Q56 HydrophobicContact CB-CB 4.46Å; D53-Q56 HydrophobicContact CB-CG 4.06Å; D53-Q56 WeakPolarHBondContact O-CB 3.43Å; D53-Q56 PolarHBondContact O-N 3.43Å; D53-Q56 PolarHBondContact OD2-NE2 3Å
54L69.9Low87.5Confident26 Ų2658.8 Ų58.814%0.13631%0.309CS..THydrogen-bonded Turntrans-69.8-21.1179.9-66.2-156.7000113.8R49 L52 Q56 M97 H98 V101R49-L54 VanDerWaalsContact NE-CD2 3.32Å; R49-L54 PolarHBondContact NH1-O 3.4Å; R49-L54 VanDerWaalsContact NH2-CA 3.3Å; L52-L54 PolarHBondContact O-N 3.46Å; L54-Q56 PolarHBondContact O-N 2.95Å; L54-M97 HydrophobicContact CD1-CG 4.49Å; L54-H98 VanDerWaalsContact CB-CE1 3.43Å; L54-H98 WeakPolarHBondContact CB-CE1 3.33Å; L54-H98 VanDerWaalsContact CB-ND1 3.3Å; L54-H98 WeakPolarHBondContact CB-ND1 3.21Å; L54-H98 VanDerWaalsContact CD1-CA 3.47Å; L54-H98 HydrophobicContact CD1-CB 3.98Å; L54-H98 WeakPolarHBondContact CD1-ND1 3.32Å; L54-H98 HydrophobicContact CG-CB 4.32Å; L54-H98 WeakPolarHBondContact CG-ND1 3.27Å; L54-V101 HydrophobicContact CD1-CG2 4.4Å; L54-V101 HydrophobicContact CD2-CB 4.04Å; L54-V101 HydrophobicContact CD2-CG1 3.72Å; L54-V101 HydrophobicContact CD2-CG2 4.37Å
55D74.5Confident87.3Confident140 Ų14063.9 Ų63.975%0.74933%0.33SS*.THydrogen-bonded Turntrans-74.4-20.9178.6-60.7-23.4000110.9D53 E57D53-D55 PolarHBondContact O-N 3.21Å; D53-D55 WeakPolarHBondContact OD1-CB 3.29Å; D53-D55 PolarHBondContact OD1-N 3.42Å; D55-E57 PolarHBondContact O-N 3.08Å
56Q76.9Confident87.2Confident100 Ų10063.9 Ų63.947%0.46733%0.33SS..SBendtrans-72.4127.2166.2-67.3175.912.500109.7R49 S51 D53 L54 G58R49-Q56 PolarHBondContact NH1-O 2.92Å; R49-Q56 VanDerWaalsContact NH1-O 3.11Å; R49-Q56 PolarHBondContact NH2-O 3.25Å; S51-Q56 PolarHBondContact OG-OE1 3.32Å; D53-Q56 HydrophobicContact CB-CB 4.46Å; D53-Q56 HydrophobicContact CB-CG 4.06Å; D53-Q56 WeakPolarHBondContact O-CB 3.43Å; D53-Q56 PolarHBondContact O-N 3.43Å; D53-Q56 PolarHBondContact OD2-NE2 3Å; L54-Q56 PolarHBondContact O-N 2.95Å; Q56-G58 PolarHBondContact O-N 3.18Å
57E75.2Confident87Confident165 Ų16566.1 Ų66.177%0.77135%0.35SS*.  trans-56.9126.5171.3-73.2-169.1153.300109.4D55D55-E57 PolarHBondContact O-N 3.08Å
58G82.9Confident86.9Confident14 Ų1465.6 Ų65.614%0.14435%0.348CS..  trans-79.1-156167.900000110.2N47 M48 Q56N47-G58 WeakPolarHBondContact OD1-CA 3.44Å; M48-G58 WeakPolarHBondContact O-CA 3.06Å; Q56-G58 PolarHBondContact O-N 3.18Å
59C92.1Very high86.8Confident15 Ų1565 Ų6510%0.10135%0.345CS..EExtended strand (participates in β ladder)trans-114.6141.6175.7-176.30000109.9N47 M48 K50 C72N47-C59 CarbonylContact C-O 3.51Å; M48-C59 WeakPolarHBondContact CA-O 3.44Å; M48-C59 WeakPolarHBondContact CB-O 3.43Å; M48-C59 PolarHBondContact N-O 3.02Å; M48-C59 PolarHBondContact O-N 2.89Å; K50-C59 HydrophobicContact CD-CB 4.31Å; C59-C72 VanDerWaalsContact C-SG 3.54Å; C59-C72 HydrophobicContact CB-CB 3.63Å; C59-C72 WeakPolarHBondContact CB-SG 3.38Å; C59-C72 WeakPolarHBondContact SG-CA 3.31Å; C59-C72 WeakPolarHBondContact SG-CB 3.38Å; C59-C72 PolarHBondContact SG-N 3.14Å; C59-C72 VanDerWaalsContact SG-N 3.36Å; C59-C72 CovalentContact SG-SG 2.02Å; C59-C72 PolarHBondContact SG-SG 3Å
60Y94.6Very high86.8Confident76 Ų7671 Ų7130%0.29837%0.374SS..EExtended strand (participates in β ladder)trans-100.3121-173.2-68.3-86000111.5K45 Y46 N47 C68K45-Y60 HydrophobicContact CB-CD1 4.04Å; K45-Y60 HydrophobicContact CB-CE1 3.99Å; K45-Y60 HydrophobicContact CD-CE1 4.17Å; Y46-Y60 CarbonylContact O-C 3.48Å; Y46-Y60 WeakPolarHBondContact O-CA 3.33Å; N47-Y60 HydrophobicContact CB-CD1 4.2Å; N47-Y60 HydrophobicContact CB-CE1 3.85Å; Y60-C68 WeakPolarHBondContact O-CB 3.5Å
61L95.1Very high87Confident3 Ų371.5 Ų71.52%0.01638%0.378CS..EExtended strand (participates in β ladder)trans-78134170.7-51.1179.2000109.2Y46 M48 L69 C72 F74 V114 M143Y46-L61 PolarHBondContact O-N 2.83Å; M48-L61 HydrophobicContact CB-CD1 4.46Å; M48-L61 HydrophobicContact CB-CD2 4.38Å; M48-L61 HydrophobicContact CB-CG 4.22Å; M48-L61 HydrophobicContact SD-CD2 4.28Å; L61-L69 HydrophobicContact CD2-CD2 4.02Å; L61-C72 HydrophobicContact CD2-CB 3.9Å; L61-F74 HydrophobicContact CD1-CD2 4.28Å; L61-F74 HydrophobicContact CD1-CE2 4.48Å; L61-V114 HydrophobicContact CD1-CG1 4.45Å; L61-V114 HydrophobicContact CD1-CG2 3.88Å; L61-M143 HydrophobicContact CB-CE 3.96Å; L61-M143 HydrophobicContact CB-SD 4.41Å
62Q93.5Very high87.5Confident85 Ų8570.2 Ų70.240%0.39737%0.369SS..  trans-136.1122.6-179.5-65.1-174.6-1.200109.5K65 C68 W146Q62-K65 HydrophobicContact CB-CB 4.2Å; Q62-K65 HydrophobicContact CB-CD 4.13Å; Q62-K65 HydrophobicContact CB-CG 4.35Å; Q62-K65 PolarHBondContact O-N 2.91Å; Q62-K65 VanDerWaalsContact O-N 3.12Å; Q62-K65 VanDerWaalsContact OE1-CD 3.22Å; Q62-K65 VanDerWaalsContact OE1-CE 3.28Å; Q62-C68 PolarHBondContact N-SG 3.04Å; Q62-W146 WeakPolarHBondContact O-CH2 3.17Å
63T92.1Very high88.1Confident57 Ų5768.6 Ų68.635%0.3537%0.374SS..THydrogen-bonded Turntrans-56.4140.2177.248.50000110.7K65 M143 W146T63-K65 PolarHBondContact O-N 3.35Å; T63-M143 HydrophobicContact CG2-CB 4.07Å; T63-M143 HydrophobicContact CG2-CE 3.78Å; T63-M143 HydrophobicContact CG2-SD 3.76Å; T63-W146 HydrophobicContact CG2-CB 4.31Å; T63-W146 HydrophobicContact CG2-CD2 4.35Å; T63-W146 HydrophobicContact CG2-CE3 4.17Å; T63-W146 HydrophobicContact CG2-CG 4.41Å
64G90.8Very high89Confident65 Ų6565.9 Ų65.967%0.6736%0.359SS*.THydrogen-bonded Turntrans74.3-5.7-17700000115.7W146G64-W146 VanDerWaalsContact N-NE1 3.17Å
65K92.4Very high90.2Very high121 Ų12167.9 Ų67.953%0.52637%0.37SS..  trans-11083.4178.7-64.7-168.4-169.9172.30111.8Q62 T63 A67 C68Q62-K65 HydrophobicContact CB-CB 4.2Å; Q62-K65 HydrophobicContact CB-CD 4.13Å; Q62-K65 HydrophobicContact CB-CG 4.35Å; Q62-K65 PolarHBondContact O-N 2.91Å; Q62-K65 VanDerWaalsContact O-N 3.12Å; Q62-K65 VanDerWaalsContact OE1-CD 3.22Å; Q62-K65 VanDerWaalsContact OE1-CE 3.28Å; T63-K65 PolarHBondContact O-N 3.35Å; K65-A67 PolarHBondContact O-N 3.12Å; K65-A67 VanDerWaalsContact O-N 3.12Å; K65-C68 PolarHBondContact O-N 3.02Å; K65-C68 VanDerWaalsContact O-N 3.07Å; K65-C68 PolarHBondContact O-SG 2.77Å
66K92.3Very high91.1Very high105 Ų10562.2 Ų62.246%0.45734%0.341SS..THydrogen-bonded Turntrans-52.9-37.2-178.2-174175.1178.9173.20114.4C68 L69K66-C68 PolarHBondContact O-N 3.4Å; K66-C68 VanDerWaalsContact O-N 3.13Å; K66-L69 WeakPolarHBondContact O-CB 3.13Å; K66-L69 PolarHBondContact O-N 3.14Å
67A93.4Very high92Very high55 Ų5562.7 Ų62.746%0.45535%0.35SS..Hα-helixtrans-55.2-32.1179.600000113.4K65 L69 E70 E71K65-A67 PolarHBondContact O-N 3.12Å; K65-A67 VanDerWaalsContact O-N 3.12Å; A67-L69 PolarHBondContact O-N 3.38Å; A67-E70 PolarHBondContact O-N 2.8Å; A67-E71 WeakPolarHBondContact O-CG 3.21Å; A67-E71 PolarHBondContact O-N 2.99Å
68C93.5Very high93Very high9 Ų955.4 Ų55.46%0.06132%0.318CS..Hα-helixtrans-64.5-29.517978.60000112.5Y60 Q62 K65 K66 E71 C72Y60-C68 WeakPolarHBondContact O-CB 3.5Å; Q62-C68 PolarHBondContact N-SG 3.04Å; K65-C68 PolarHBondContact O-N 3.02Å; K65-C68 VanDerWaalsContact O-N 3.07Å; K65-C68 PolarHBondContact O-SG 2.77Å; K66-C68 PolarHBondContact O-N 3.4Å; K66-C68 VanDerWaalsContact O-N 3.13Å; C68-E71 PolarHBondContact O-N 3.16Å; C68-C72 WeakPolarHBondContact O-CB 3.18Å; C68-C72 PolarHBondContact O-N 3.23Å; C68-C72 PolarHBondContact O-SG 2.87Å
69L93.5Very high93.6Very high1 Ų158.8 Ų58.81%0.00533%0.329CS..Hα-helixtrans-67-41.7179.2-59.1178.8000110.9L61 K66 A67 G73 F74 W146 L147 E150 H151L61-L69 HydrophobicContact CD2-CD2 4.02Å; K66-L69 WeakPolarHBondContact O-CB 3.13Å; K66-L69 PolarHBondContact O-N 3.14Å; A67-L69 PolarHBondContact O-N 3.38Å; L69-G73 PolarHBondContact O-N 3.43Å; L69-G73 VanDerWaalsContact O-N 3.1Å; L69-F74 HydrophobicContact CB-CB 4.29Å; L69-F74 HydrophobicContact CD2-CB 4.16Å; L69-F74 HydrophobicContact CD2-CD1 4.43Å; L69-F74 HydrophobicContact CD2-CG 4.22Å; L69-F74 PolarHBondContact O-N 2.84Å; L69-W146 HydrophobicContact CD1-CH2 3.74Å; L69-W146 HydrophobicContact CD1-CZ2 4.13Å; L69-W146 HydrophobicContact CD1-CZ3 4.3Å; L69-W146 HydrophobicContact CD2-CH2 3.76Å; L69-W146 HydrophobicContact CD2-CZ3 3.87Å; L69-W146 HydrophobicContact CG-CH2 3.72Å; L69-W146 HydrophobicContact CG-CZ2 4.46Å; L69-W146 HydrophobicContact CG-CZ3 4.32Å; L69-L147 HydrophobicContact CD1-CD2 4.29Å; L69-L147 HydrophobicContact CD2-CD2 3.6Å; L69-E150 HydrophobicContact CD1-CB 4.41Å; L69-H151 HydrophobicContact CD1-CB 4.41Å; L69-H151 WeakPolarHBondContact CD1-CD2 3.47Å
70E92Very high93.9Very high142 Ų14258.1 Ų58.166%0.66432%0.324SS*.Hα-helixtrans-68.5-46.8175.9-65178.9-174.100110.9A67 C72 G73A67-E70 PolarHBondContact O-N 2.8Å; E70-C72 VanDerWaalsContact C-N 3.31Å; E70-C72 PolarHBondContact O-N 2.91Å; E70-G73 PolarHBondContact O-N 3.04Å; E70-G73 VanDerWaalsContact O-N 3.09Å
71E92Very high94.1Very high134 Ų13454.5 Ų54.563%0.62631%0.31SS*.Hα-helixtrans-61.2-38.8177.6-71.9172.9-171.200112.5K50 A67 C68 G73K50-E71 PolarHBondContact NZ-O 2.82Å; A67-E71 WeakPolarHBondContact O-CG 3.21Å; A67-E71 PolarHBondContact O-N 2.99Å; C68-E71 PolarHBondContact O-N 3.16Å; E71-G73 VanDerWaalsContact C-N 3.29Å
72C93.4Very high94.3Very high6 Ų654.4 Ų54.44%0.04131%0.309CS..Hα-helixtrans-77.6-15.9178-62.40000112.9M48 K50 C59 L61 C68 E70 F74M48-C72 HydrophobicContact SD-CB 3.79Å; K50-C72 WeakPolarHBondContact CE-O 3.24Å; C59-C72 VanDerWaalsContact C-SG 3.54Å; C59-C72 HydrophobicContact CB-CB 3.63Å; C59-C72 WeakPolarHBondContact CB-SG 3.38Å; C59-C72 WeakPolarHBondContact SG-CA 3.31Å; C59-C72 WeakPolarHBondContact SG-CB 3.38Å; C59-C72 PolarHBondContact SG-N 3.14Å; C59-C72 VanDerWaalsContact SG-N 3.36Å; C59-C72 CovalentContact SG-SG 2.02Å; C59-C72 PolarHBondContact SG-SG 3Å; L61-C72 HydrophobicContact CD2-CB 3.9Å; C68-C72 WeakPolarHBondContact O-CB 3.18Å; C68-C72 PolarHBondContact O-N 3.23Å; C68-C72 PolarHBondContact O-SG 2.87Å; E70-C72 VanDerWaalsContact C-N 3.31Å; E70-C72 PolarHBondContact O-N 2.91Å; C72-F74 VanDerWaalsContact C-N 3.35Å
73G93.6Very high94.6Very high53 Ų5350.4 Ų50.455%0.54629%0.291SS..THydrogen-bonded Turntrans67.835.9-173.200000112.1L69 E70 E71 N75L69-G73 PolarHBondContact O-N 3.43Å; L69-G73 VanDerWaalsContact O-N 3.1Å; E70-G73 PolarHBondContact O-N 3.04Å; E70-G73 VanDerWaalsContact O-N 3.09Å; E71-G73 VanDerWaalsContact C-N 3.29Å; G73-N75 PolarHBondContact O-N 2.84Å
74F95.6Very high94.9Very high12 Ų1247.7 Ų47.75%0.05327%0.274CS..  trans-64.5123.8-179.3-175.4-91.4000110.9M48 L61 L69 C72 T80 N112 L147 L153M48-F74 HydrophobicContact SD-CB 4.28Å; M48-F74 HydrophobicContact SD-CD2 4.01Å; L61-F74 HydrophobicContact CD1-CD2 4.28Å; L61-F74 HydrophobicContact CD1-CE2 4.48Å; L69-F74 HydrophobicContact CB-CB 4.29Å; L69-F74 HydrophobicContact CD2-CB 4.16Å; L69-F74 HydrophobicContact CD2-CD1 4.43Å; L69-F74 HydrophobicContact CD2-CG 4.22Å; L69-F74 PolarHBondContact O-N 2.84Å; C72-F74 VanDerWaalsContact C-N 3.35Å; F74-T80 HydrophobicContact CE2-CG2 4.08Å; F74-T80 HydrophobicContact CZ-CG2 4.27Å; F74-N112 HydrophobicContact CD2-CB 3.95Å; F74-N112 HydrophobicContact CE2-CB 3.78Å; F74-L147 HydrophobicContact CE1-CD2 4.15Å; F74-L147 HydrophobicContact CE2-CD1 4.47Å; F74-L147 HydrophobicContact CZ-CD1 4.2Å; F74-L147 HydrophobicContact CZ-CD2 4.17Å; F74-L153 HydrophobicContact CE1-CD1 4.49Å; F74-L153 HydrophobicContact CZ-CD1 4.14Å; F74-L153 HydrophobicContact CZ-CD2 4.4Å
75N95Very high95.2Very high68 Ų6844.8 Ų44.836%0.36424%0.243SC..  trans-110.5104.9178.9-177.70.9000111G73 T77 S78 N112G73-N75 PolarHBondContact O-N 2.84Å; N75-T77 PolarHBondContact ND2-OG1 3.48Å; N75-T77 PolarHBondContact O-N 3.25Å; N75-T77 PolarHBondContact OD1-N 3.46Å; N75-T77 PolarHBondContact OD1-OG1 2.9Å; N75-S78 PolarHBondContact ND2-OG 3.04Å; N75-S78 VanDerWaalsContact ND2-OG 3.08Å; N75-S78 WeakPolarHBondContact O-CB 3.33Å; N75-S78 PolarHBondContact O-N 3.4Å; N75-S78 VanDerWaalsContact O-N 3.13Å; N75-N112 PolarHBondContact N-OD1 2.93Å; N75-N112 PolarHBondContact O-ND2 2.91Å
76S94.1Very high95.3Very high21 Ų2139.2 Ų39.215%0.14722%0.22CC..THydrogen-bonded Turntrans-67.8-15.3-179.254.30000114.8H151 P154S76-H151 WeakPolarHBondContact CB-O 3.14Å; S76-H151 PolarHBondContact OG-O 3.18Å; S76-P154 WeakPolarHBondContact O-CD 3.24Å
77T94.3Very high95.4Very high109 Ų10937.1 Ų37.167%0.66921%0.209SC*.THydrogen-bonded Turntrans-81.7-22.3174.566.20000112.7N75N75-T77 PolarHBondContact ND2-OG1 3.48Å; N75-T77 PolarHBondContact O-N 3.25Å; N75-T77 PolarHBondContact OD1-N 3.46Å; N75-T77 PolarHBondContact OD1-OG1 2.9Å
78S96.1Very high95Very high13 Ų1334.9 Ų34.99%0.09119%0.189CC..SBendtrans-77.5159.9174.7-69.30000111.7N75 E110N75-S78 PolarHBondContact ND2-OG 3.04Å; N75-S78 VanDerWaalsContact ND2-OG 3.08Å; N75-S78 WeakPolarHBondContact O-CB 3.33Å; N75-S78 PolarHBondContact O-N 3.4Å; N75-S78 VanDerWaalsContact O-N 3.13Å; S78-E110 WeakPolarHBondContact CB-O 3.43Å; S78-E110 PolarHBondContact OG-O 3.42Å
79K97.4Very high94.3Very high85 Ų8539.1 Ų39.137%0.3721%0.21SC..  trans-57.3142.5166.2-71-176.2-169.1157.40110.5E108 A111 N112 N157 Y315K79-E108 WeakPolarHBondContact CD-OE2 3.18Å; K79-E108 IonicContact NZ-OE1 3.74Å; K79-E108 PolarHBondContact NZ-OE1 3.32Å; K79-E108 VanDerWaalsContact NZ-OE1 3.14Å; K79-E108 IonicContact NZ-OE2 2.92Å; K79-E108 PolarHBondContact NZ-OE2 2.84Å; K79-A111 HydrophobicContact CB-CB 4.08Å; K79-A111 CarbonylContact O-C 3.49Å; K79-A111 VanDerWaalsContact O-CA 3.24Å; K79-A111 WeakPolarHBondContact O-CA 3.32Å; K79-A111 WeakPolarHBondContact O-CB 3.43Å; K79-N112 PolarHBondContact O-N 2.88Å; K79-N157 WeakPolarHBondContact CA-O 3.47Å; K79-Y315 PolarHBondContact NZ-OH 3.21Å
80T98.4Very high93.6Very high0 Ų042 Ų420%023%0.23CC..EExtended strand (participates in β ladder)trans-118.6115.7176.4-640000108.8F74 F82 N112 N157 V158 H159F74-T80 HydrophobicContact CE2-CG2 4.08Å; F74-T80 HydrophobicContact CZ-CG2 4.27Å; T80-F82 HydrophobicContact CG2-CD1 3.82Å; T80-F82 HydrophobicContact CG2-CE1 3.47Å; T80-F82 VanDerWaalsContact CG2-CE1 3.47Å; T80-N112 HydrophobicContact CG2-CB 4.32Å; T80-N112 PolarHBondContact OG1-ND2 3.2Å; T80-N157 PolarHBondContact N-O 2.84Å; T80-V158 WeakPolarHBondContact O-CA 3.5Å; T80-H159 PolarHBondContact O-N 2.86Å
81I98.8Very high93.1Very high1 Ų136.3 Ų36.31%0.00521%0.209CC..EExtended strand (participates in β ladder)trans-117.5115.4-171.9-53.3179.1000108.9I83 V104 E108 A111 N112 V113 V114 H159 I161I81-I83 HydrophobicContact CG2-CG1 4.49Å; I81-V104 HydrophobicContact CB-CG1 4.39Å; I81-V104 HydrophobicContact CD1-CG1 3.71Å; I81-V104 HydrophobicContact CG2-CG1 4.06Å; I81-E108 HydrophobicContact CD1-CB 4.25Å; I81-E108 HydrophobicContact CD1-CG 4.09Å; I81-A111 HydrophobicContact CD1-CB 4.16Å; I81-A111 HydrophobicContact CG1-CB 4.42Å; I81-N112 PolarHBondContact N-O 2.85Å; I81-V113 WeakPolarHBondContact O-CA 3.48Å; I81-V114 PolarHBondContact O-N 2.81Å; I81-H159 CarbonylContact C-O 3.54Å; I81-H159 VanDerWaalsContact CA-O 3.28Å; I81-H159 WeakPolarHBondContact CA-O 3.48Å; I81-H159 HydrophobicContact CG1-CB 4.31Å; I81-I161 HydrophobicContact CG2-CD1 3.67Å; I81-I161 HydrophobicContact CG2-CG1 4.27Å
82F98.8Very high92.6Very high0 Ų035.5 Ų35.50%021%0.208CC..EExtended strand (participates in β ladder)trans-102.3127.7176.5-81.339.6000109Y46 T80 V114 V116 I140 M143 F144 H159 L160 I161Y46-F82 HydrophobicContact CD1-CD2 4.35Å; Y46-F82 AromaticContact CD1-CE2 3.64Å; Y46-F82 HydrophobicContact CD1-CE2 3.64Å; Y46-F82 HydrophobicContact CD1-CZ 4.4Å; Y46-F82 HydrophobicContact CE1-CD2 4.49Å; Y46-F82 AromaticContact CE1-CE2 3.88Å; Y46-F82 HydrophobicContact CE1-CE2 3.88Å; T80-F82 HydrophobicContact CG2-CD1 3.82Å; T80-F82 HydrophobicContact CG2-CE1 3.47Å; T80-F82 VanDerWaalsContact CG2-CE1 3.47Å; F82-V114 CarbonylContact C-O 3.48Å; F82-V114 VanDerWaalsContact CA-O 3.31Å; F82-V114 WeakPolarHBondContact CA-O 3.45Å; F82-V114 HydrophobicContact CD1-CB 3.63Å; F82-V114 HydrophobicContact CD1-CG1 4.35Å; F82-V114 HydrophobicContact CD1-CG2 3.9Å; F82-V114 HydrophobicContact CD2-CB 4.49Å; F82-V114 HydrophobicContact CD2-CG1 4.44Å; F82-V114 HydrophobicContact CE1-CB 3.61Å; F82-V114 HydrophobicContact CE1-CG1 4.1Å; F82-V114 HydrophobicContact CE1-CG2 3.48Å; F82-V114 VanDerWaalsContact CE1-CG2 3.48Å; F82-V114 HydrophobicContact CE2-CB 4.5Å; F82-V114 HydrophobicContact CE2-CG1 4.21Å; F82-V114 HydrophobicContact CG-CB 4.08Å; F82-V114 HydrophobicContact CZ-CB 4.07Å; F82-V114 HydrophobicContact CZ-CG1 4.03Å; F82-V114 HydrophobicContact CZ-CG2 4.08Å; F82-V116 HydrophobicContact CB-CG2 4.23Å; F82-V116 HydrophobicContact CD2-CG2 3.55Å; F82-V116 HydrophobicContact CE2-CG2 4.31Å; F82-V116 HydrophobicContact CG-CG2 4.24Å; F82-I140 HydrophobicContact CD2-CG2 4.27Å; F82-I140 HydrophobicContact CE2-CG2 4.5Å; F82-M143 HydrophobicContact CE2-CG 4.33Å; F82-M143 HydrophobicContact CZ-CG 4.33Å; F82-F144 HydrophobicContact CB-CZ 4.46Å; F82-F144 HydrophobicContact CD1-CE1 4.03Å; F82-F144 AromaticContact CD1-CZ 3.92Å; F82-F144 HydrophobicContact CD1-CZ 3.92Å; F82-F144 HydrophobicContact CD2-CE1 4.25Å; F82-F144 HydrophobicContact CD2-CE2 4.39Å; F82-F144 AromaticContact CD2-CZ 3.62Å; F82-F144 HydrophobicContact CD2-CZ 3.62Å; F82-F144 AromaticContact CE1-CE1 3.73Å; F82-F144 HydrophobicContact CE1-CE1 3.73Å; F82-F144 HydrophobicContact CE1-CZ 4.01Å; F82-F144 AromaticContact CE2-CE1 3.94Å; F82-F144 HydrophobicContact CE2-CE1 3.94Å; F82-F144 AromaticContact CE2-CZ 3.7Å; F82-F144 HydrophobicContact CE2-CZ 3.7Å; F82-F144 HydrophobicContact CG-CE1 4.31Å; F82-F144 AromaticContact CG-CZ 3.75Å; F82-F144 HydrophobicContact CG-CZ 3.75Å; F82-F144 AromaticContact CZ-CE1 3.68Å; F82-F144 HydrophobicContact CZ-CE1 3.68Å; F82-F144 AromaticContact CZ-CZ 3.92Å; F82-F144 HydrophobicContact CZ-CZ 3.92Å; F82-H159 PolarHBondContact N-O 3.33Å; F82-L160 HydrophobicContact CB-CD2 3.65Å; F82-L160 HydrophobicContact CG-CD2 4.24Å; F82-L160 CarbonylContact O-C 3.53Å; F82-L160 WeakPolarHBondContact O-CA 3.29Å; F82-I161 PolarHBondContact O-N 3.2Å
83I98.6Very high92.2Very high1 Ų138.5 Ų38.51%0.00522%0.22CC..EExtended strand (participates in β ladder)trans-108.1122.3176.7-57.4165.9000108.2I81 M97 L100 V101 V104 V113 V114 V116 I161I81-I83 HydrophobicContact CG2-CG1 4.49Å; I83-M97 HydrophobicContact CB-CE 3.76Å; I83-M97 HydrophobicContact CG2-CE 3.32Å; I83-M97 HydrophobicContact CG2-SD 3.78Å; I83-L100 HydrophobicContact CD1-CG 4.27Å; I83-L100 HydrophobicContact CG2-CD2 3.6Å; I83-L100 HydrophobicContact CG2-CG 4.41Å; I83-V101 HydrophobicContact CD1-CB 4.39Å; I83-V101 HydrophobicContact CD1-CG2 3.77Å; I83-V104 HydrophobicContact CD1-CB 4.46Å; I83-V104 HydrophobicContact CD1-CG2 4.26Å; I83-V113 HydrophobicContact CD1-CG1 3.97Å; I83-V114 PolarHBondContact N-O 2.54Å; I83-V116 PolarHBondContact O-N 3.24Å; I83-I161 WeakPolarHBondContact CA-O 3.47Å; I83-I161 HydrophobicContact CG1-CB 4.47Å; I83-I161 HydrophobicContact CG1-CD1 4.42Å
84I98.6Very high91.7Very high0 Ų037.4 Ų37.40%020%0.201CC..EExtended strand (participates in β ladder)trans-120.3115.3-170.2-49.1172.7000108.6V116 I140 L160 I161 G162 Y163 V169 A170I84-V116 HydrophobicContact CG1-CB 4.13Å; I84-V116 HydrophobicContact CG1-CG2 3.94Å; I84-I140 HydrophobicContact CD1-CD1 3.8Å; I84-I140 HydrophobicContact CG1-CD1 4.45Å; I84-L160 HydrophobicContact CD1-CB 4.48Å; I84-I161 PolarHBondContact N-O 3.06Å; I84-G162 WeakPolarHBondContact O-CA 3.45Å; I84-Y163 PolarHBondContact O-N 2.87Å; I84-V169 HydrophobicContact CD1-CG1 4.34Å; I84-V169 HydrophobicContact CG2-CB 4.07Å; I84-V169 HydrophobicContact CG2-CG1 3.8Å; I84-A170 HydrophobicContact CD1-CB 3.95Å
85H97.2Very high91.2Very high5 Ų541.4 Ų41.42%0.02323%0.227CC..  trans-77.1170.8-179.869.986.4000112.6F93 W96 V116 W118 G166H85-F93 AromaticContact CD2-CE1 3.47Å; H85-F93 VanDerWaalsContact CD2-CE1 3.47Å; H85-F93 WeakPolarHBondContact CD2-CE1 3.4Å; H85-F93 AromaticContact NE2-CE1 3.8Å; H85-W96 HydrophobicContact CB-CH2 4.03Å; H85-W96 HydrophobicContact CB-CZ2 4.34Å; H85-V116 PolarHBondContact CD2-O 2.93Å; H85-W118 AromaticContact CD2-CD1 3.63Å; H85-W118 AromaticContact CD2-NE1 3.78Å; H85-W118 AromaticContact CE1-CD1 3.41Å; H85-W118 VanDerWaalsContact CE1-CD1 3.41Å; H85-W118 AromaticContact CE1-CE2 3.87Å; H85-W118 AromaticContact CE1-CG 3.92Å; H85-W118 AromaticContact CE1-NE1 3.36Å; H85-W118 PolarHBondContact CE1-NE1 2.88Å; H85-W118 AromaticContact CG-NE1 3.79Å; H85-W118 AromaticContact ND1-CD1 3.98Å; H85-W118 AromaticContact ND1-NE1 3.52Å; H85-W118 AromaticContact NE2-CD1 3.17Å; H85-W118 AromaticContact NE2-CG 3.84Å; H85-W118 PolarHBondContact NE2-N 3.15Å; H85-W118 VanDerWaalsContact NE2-N 3.15Å; H85-W118 AromaticContact NE2-NE1 3.55Å; H85-W118 WeakPolarHBondContact O-CZ2 3.39Å; H85-W118 PolarHBondContact O-NE1 2.92Å; H85-G166 VanDerWaalsContact O-CA 3.25Å; H85-G166 WeakPolarHBondContact O-CA 3.5Å; H85-G166 PolarHBondContact O-N 2.93Å
86G95Very high90.8Very high3 Ų338.4 Ų38.43%0.03121%0.21CC..  trans-101.1-161.117900000114.4Y163G86-Y163 VanDerWaalsContact CA-O 3.3Å; G86-Y163 WeakPolarHBondContact CA-O 3.34Å; G86-Y163 PolarHBondContact N-O 3.21Å
87W93.5Very high90.7Very high61 Ų6137.4 Ų37.423%0.23120%0.203CC..  trans-64.1145.1173.4-178.271.2000112M89 Q124 Y126 L165 M261W87-M89 HydrophobicContact CH2-CG 3.36Å; W87-M89 HydrophobicContact CH2-SD 3.93Å; W87-M89 HydrophobicContact CZ2-CG 3.37Å; W87-M89 HydrophobicContact CZ2-SD 3.29Å; W87-M89 WeakPolarHBondContact CZ2-SD 3.34Å; W87-M89 HydrophobicContact CZ3-CG 4.13Å; W87-Q124 PolarHBondContact NE1-O 3.23Å; W87-Y126 HydrophobicContact CD2-CD2 4.13Å; W87-Y126 HydrophobicContact CG-CD2 4.11Å; W87-L165 HydrophobicContact CB-CD1 3.69Å; W87-L165 HydrophobicContact CB-CG 4.1Å; W87-L165 HydrophobicContact CG-CD1 4.42Å; W87-M261 HydrophobicContact CZ3-CE 4.4Å
88T85.4Confident90.5Very high8 Ų835.7 Ų35.75%0.04919%0.187CC..  trans-154144.3173.4176.90000111.7S90 M119 Q123T88-S90 PolarHBondContact OG1-N 3.43Å; T88-S90 PolarHBondContact OG1-OG 3.38Å; T88-M119 HydrophobicContact CG2-CE 4.24Å; T88-M119 HydrophobicContact CG2-SD 3.24Å; T88-M119 WeakPolarHBondContact CG2-SD 3.29Å; T88-Q123 VanDerWaalsContact O-CA 3.28Å; T88-Q123 WeakPolarHBondContact O-CA 3.33Å; T88-Q123 WeakPolarHBondContact O-CG 3.38Å
89M78.4Confident90.3Very high99 Ų9940.2 Ų40.249%0.48821%0.206SC..SBendtrans-93.5-17.6173.4-71.2-60.7-58.200113.5W87W87-M89 HydrophobicContact CH2-CG 3.36Å; W87-M89 HydrophobicContact CH2-SD 3.93Å; W87-M89 HydrophobicContact CZ2-CG 3.37Å; W87-M89 HydrophobicContact CZ2-SD 3.29Å; W87-M89 WeakPolarHBondContact CZ2-SD 3.34Å; W87-M89 HydrophobicContact CZ3-CG 4.13Å
90S80.3Confident90.2Very high62 Ų6236.2 Ų36.243%0.43419%0.188SC..SBendtrans-82.1-18.6-174.859.80000113.3T88 I92T88-S90 PolarHBondContact OG1-N 3.43Å; T88-S90 PolarHBondContact OG1-OG 3.38Å; S90-I92 PolarHBondContact O-N 3.11Å; S90-I92 WeakPolarHBondContact OG-CG1 3.46Å; S90-I92 PolarHBondContact OG-O 3.3Å
91G80.1Confident90Very high22 Ų2236.2 Ų36.223%0.22719%0.188CC..SBendtrans69.611.5-175.900000114.3M119G91-M119 VanDerWaalsContact C-SD 3.51Å; G91-M119 WeakPolarHBondContact O-CG 3.4Å
92I82.4Confident89.8Confident117 Ų11737.4 Ų37.460%0.620%0.197SC*.SBendtrans-126.6151.3177.760.2170.7000110S90S90-I92 PolarHBondContact O-N 3.11Å; S90-I92 WeakPolarHBondContact OG-CG1 3.46Å; S90-I92 PolarHBondContact OG-O 3.3Å
93F84.6Confident89.7Confident68 Ų6837.6 Ų37.630%0.29820%0.198SC..  trans-62.5138.2172.7-65.8-53000110.9H85 M97 V115 D117 M119H85-F93 AromaticContact CD2-CE1 3.47Å; H85-F93 VanDerWaalsContact CD2-CE1 3.47Å; H85-F93 WeakPolarHBondContact CD2-CE1 3.4Å; H85-F93 AromaticContact NE2-CE1 3.8Å; F93-M97 HydrophobicContact CB-CB 4.24Å; F93-M97 HydrophobicContact CB-CG 4.43Å; F93-M97 HydrophobicContact CD1-CG 4.48Å; F93-M97 HydrophobicContact CG-CG 4.43Å; F93-V115 HydrophobicContact CZ-CG1 4.25Å; F93-D117 HydrophobicContact CZ-CB 3.89Å; F93-M119 HydrophobicContact CD1-CE 3.55Å; F93-M119 HydrophobicContact CE1-CE 3.57Å; F93-M119 HydrophobicContact CG-CE 4.15Å; F93-M119 HydrophobicContact CZ-CE 4.21Å
94E82.8Confident89.6Confident31 Ų3137.5 Ų37.515%0.14520%0.198CC..  trans-77.2155.5175.6-66.7-178.3146.500110.7W96 M97 K265E94-W96 VanDerWaalsContact CB-CD1 3.41Å; E94-W96 HydrophobicContact CB-CG 4.3Å; E94-W96 VanDerWaalsContact CB-NE1 3.29Å; E94-W96 PolarHBondContact O-N 3.36Å; E94-W96 PolarHBondContact OE2-NE1 2.77Å; E94-M97 VanDerWaalsContact O-CB 3.25Å; E94-M97 WeakPolarHBondContact O-CB 3.28Å; E94-M97 PolarHBondContact O-N 2.95Å; E94-K265 WeakPolarHBondContact OE1-CE 3.22Å; E94-K265 IonicContact OE1-NZ 3.53Å; E94-K265 PolarHBondContact OE1-NZ 3Å
95T85.3Confident89.4Confident95 Ų9539 Ų3958%0.58321%0.205SC*.Hα-helixtrans-60.9-24.1-173.766.10000113.8M97 H98T95-M97 PolarHBondContact O-N 2.82Å; T95-H98 PolarHBondContact O-N 2.8Å
96W87.8Confident89.2Confident5 Ų543.6 Ų43.62%0.01923%0.227CC..Hα-helixtrans-63.6-27.6175.567.4-107.1000112.2H85 E94 K99 L100 Y163 E269 V272H85-W96 HydrophobicContact CB-CH2 4.03Å; H85-W96 HydrophobicContact CB-CZ2 4.34Å; E94-W96 VanDerWaalsContact CB-CD1 3.41Å; E94-W96 HydrophobicContact CB-CG 4.3Å; E94-W96 VanDerWaalsContact CB-NE1 3.29Å; E94-W96 PolarHBondContact O-N 3.36Å; E94-W96 PolarHBondContact OE2-NE1 2.77Å; W96-K99 PolarHBondContact O-N 2.92Å; W96-L100 HydrophobicContact CE3-CB 4.46Å; W96-L100 HydrophobicContact CE3-CD2 4.44Å; W96-L100 HydrophobicContact CZ3-CD2 4.13Å; W96-L100 WeakPolarHBondContact O-CB 3.36Å; W96-L100 PolarHBondContact O-N 3.06Å; W96-Y163 AromaticContact CE2-CD1 3.83Å; W96-Y163 AromaticContact CE2-CE1 3.84Å; W96-Y163 AromaticContact CH2-CD1 3.77Å; W96-Y163 HydrophobicContact CH2-CD1 3.77Å; W96-Y163 HydrophobicContact CH2-CG 4.16Å; W96-Y163 AromaticContact CZ2-CD1 3.27Å; W96-Y163 HydrophobicContact CZ2-CD1 3.27Å; W96-Y163 AromaticContact CZ2-CE1 3.68Å; W96-Y163 HydrophobicContact CZ2-CE1 3.68Å; W96-Y163 HydrophobicContact CZ2-CG 4.05Å; W96-Y163 AromaticContact NE1-CE1 3.78Å; W96-E269 VanDerWaalsContact CD1-CD 3.46Å; W96-V272 HydrophobicContact CB-CG1 4.11Å; W96-V272 HydrophobicContact CD2-CG1 4.09Å; W96-V272 HydrophobicContact CD2-CG2 4.07Å; W96-V272 HydrophobicContact CE3-CB 4.35Å; W96-V272 HydrophobicContact CE3-CG1 3.55Å; W96-V272 HydrophobicContact CE3-CG2 3.98Å; W96-V272 HydrophobicContact CG-CG1 4.33Å; W96-V272 HydrophobicContact CG-CG2 4.43Å; W96-V272 HydrophobicContact CZ3-CG1 4.38Å
97M90.7Very high89.2Confident1 Ų146.2 Ų46.21%0.00524%0.235CC..Hα-helixtrans-63.1-45.6179.9-171.666.3-162.700110.8L54 I83 F93 E94 T95 K99 L100 V101 V115L54-M97 HydrophobicContact CD1-CG 4.49Å; I83-M97 HydrophobicContact CB-CE 3.76Å; I83-M97 HydrophobicContact CG2-CE 3.32Å; I83-M97 HydrophobicContact CG2-SD 3.78Å; F93-M97 HydrophobicContact CB-CB 4.24Å; F93-M97 HydrophobicContact CB-CG 4.43Å; F93-M97 HydrophobicContact CD1-CG 4.48Å; F93-M97 HydrophobicContact CG-CG 4.43Å; E94-M97 VanDerWaalsContact O-CB 3.25Å; E94-M97 WeakPolarHBondContact O-CB 3.28Å; E94-M97 PolarHBondContact O-N 2.95Å; T95-M97 PolarHBondContact O-N 2.82Å; M97-K99 VanDerWaalsContact C-N 3.32Å; M97-K99 PolarHBondContact O-N 3.5Å; M97-L100 PolarHBondContact O-N 3.38Å; M97-V101 HydrophobicContact CE-CG2 3.51Å; M97-V101 HydrophobicContact CG-CG2 4.43Å; M97-V101 VanDerWaalsContact O-CG2 3.3Å; M97-V101 WeakPolarHBondContact O-CG2 3.47Å; M97-V101 PolarHBondContact O-N 3.2Å; M97-V101 HydrophobicContact SD-CG2 4.46Å; M97-V115 HydrophobicContact CE-CB 3.97Å; M97-V115 HydrophobicContact CE-CG1 3.45Å; M97-V115 VanDerWaalsContact CE-CG1 3.45Å; M97-V115 HydrophobicContact CE-CG2 3.42Å; M97-V115 VanDerWaalsContact CE-CG2 3.42Å
98H89.9Confident89.3Confident72 Ų7245 Ų4533%0.33323%0.232SC..Hα-helixtrans-57.1-45.8174.8-63.8-104.8000111.5L54 T95 S102L54-H98 VanDerWaalsContact CB-CE1 3.43Å; L54-H98 WeakPolarHBondContact CB-CE1 3.33Å; L54-H98 VanDerWaalsContact CB-ND1 3.3Å; L54-H98 WeakPolarHBondContact CB-ND1 3.21Å; L54-H98 VanDerWaalsContact CD1-CA 3.47Å; L54-H98 HydrophobicContact CD1-CB 3.98Å; L54-H98 WeakPolarHBondContact CD1-ND1 3.32Å; L54-H98 HydrophobicContact CG-CB 4.32Å; L54-H98 WeakPolarHBondContact CG-ND1 3.27Å; T95-H98 PolarHBondContact O-N 2.8Å; H98-S102 WeakPolarHBondContact O-CB 3.25Å; H98-S102 PolarHBondContact O-N 3.09Å
99K92.3Very high89.6Confident109 Ų10951 Ų5147%0.47426%0.264SS..Hα-helixtrans-65.7-42179.8-63.2177-176169.10111.7W96 M97 A103W96-K99 PolarHBondContact O-N 2.92Å; M97-K99 VanDerWaalsContact C-N 3.32Å; M97-K99 PolarHBondContact O-N 3.5Å; K99-A103 VanDerWaalsContact O-CB 3.25Å; K99-A103 WeakPolarHBondContact O-CB 3.31Å; K99-A103 PolarHBondContact O-N 3.48Å
100L95.7Very high90.3Very high0 Ų053.3 Ų53.30%027%0.274CS..Hα-helixtrans-66.3-52.2179.5179.460.6000111.8I83 W96 M97 S102 A103 V104 I161 L187 V272 F275 V276 L279I83-L100 HydrophobicContact CD1-CG 4.27Å; I83-L100 HydrophobicContact CG2-CD2 3.6Å; I83-L100 HydrophobicContact CG2-CG 4.41Å; W96-L100 HydrophobicContact CE3-CB 4.46Å; W96-L100 HydrophobicContact CE3-CD2 4.44Å; W96-L100 HydrophobicContact CZ3-CD2 4.13Å; W96-L100 WeakPolarHBondContact O-CB 3.36Å; W96-L100 PolarHBondContact O-N 3.06Å; M97-L100 PolarHBondContact O-N 3.38Å; L100-S102 VanDerWaalsContact C-N 3.32Å; L100-S102 PolarHBondContact O-N 2.84Å; L100-A103 PolarHBondContact O-N 3.4Å; L100-V104 HydrophobicContact CD1-CG2 4.03Å; L100-V104 HydrophobicContact CG-CG2 4.47Å; L100-V104 WeakPolarHBondContact O-CG2 3.48Å; L100-V104 PolarHBondContact O-N 3.47Å; L100-I161 HydrophobicContact CD2-CG2 4.13Å; L100-L187 HydrophobicContact CD2-CD1 4.31Å; L100-V272 HydrophobicContact CB-CG1 4.03Å; L100-V272 HydrophobicContact CD2-CG1 4.12Å; L100-V272 HydrophobicContact CG-CG1 4.47Å; L100-F275 HydrophobicContact CD1-CD1 3.68Å; L100-F275 HydrophobicContact CD1-CE1 4.18Å; L100-V276 HydrophobicContact CB-CG2 4.13Å; L100-V276 HydrophobicContact CD1-CG2 3.92Å; L100-L279 HydrophobicContact CD1-CD1 4.37Å
101V95Very high91.1Very high0 Ų051.1 Ų51.10%026%0.26CS..Hα-helixtrans-57.7-48.1178.8175.30000110.4R49 L54 I83 M97 A103 V104 M105 V113 V115R49-V101 HydrophobicContact CB-CG1 4.41Å; R49-V101 HydrophobicContact CG-CG1 3.86Å; L54-V101 HydrophobicContact CD1-CG2 4.4Å; L54-V101 HydrophobicContact CD2-CB 4.04Å; L54-V101 HydrophobicContact CD2-CG1 3.72Å; L54-V101 HydrophobicContact CD2-CG2 4.37Å; I83-V101 HydrophobicContact CD1-CB 4.39Å; I83-V101 HydrophobicContact CD1-CG2 3.77Å; M97-V101 HydrophobicContact CE-CG2 3.51Å; M97-V101 HydrophobicContact CG-CG2 4.43Å; M97-V101 VanDerWaalsContact O-CG2 3.3Å; M97-V101 WeakPolarHBondContact O-CG2 3.47Å; M97-V101 PolarHBondContact O-N 3.2Å; M97-V101 HydrophobicContact SD-CG2 4.46Å; V101-A103 PolarHBondContact O-N 3.26Å; V101-V104 PolarHBondContact O-N 3.26Å; V101-M105 HydrophobicContact CG1-CG 4.26Å; V101-M105 HydrophobicContact CG1-SD 3.79Å; V101-M105 WeakPolarHBondContact O-CB 3.46Å; V101-M105 WeakPolarHBondContact O-CG 3.45Å; V101-M105 PolarHBondContact O-N 3.25Å; V101-V113 HydrophobicContact CG1-CG1 4.31Å; V101-V115 HydrophobicContact CG2-CG2 3.67Å
102S94.1Very high91.9Very high27 Ų2750.3 Ų50.319%0.18925%0.25CC..Hα-helixtrans-60-44.4179.3-172.90000111.9H98 L100 M105 Q106H98-S102 WeakPolarHBondContact O-CB 3.25Å; H98-S102 PolarHBondContact O-N 3.09Å; L100-S102 VanDerWaalsContact C-N 3.32Å; L100-S102 PolarHBondContact O-N 2.84Å; S102-M105 PolarHBondContact O-N 2.98Å; S102-Q106 WeakPolarHBondContact O-CB 3.21Å; S102-Q106 WeakPolarHBondContact O-CG 3.35Å; S102-Q106 PolarHBondContact O-N 3.24Å; S102-Q106 PolarHBondContact O-NE2 2.91Å; S102-Q106 PolarHBondContact OG-NE2 3.04Å
103A95.3Very high92.6Very high3 Ų344.8 Ų44.83%0.02522%0.222CC..Hα-helixtrans-65.5-39177.800000112.7K99 L100 V101 R107 V276 L279 M280K99-A103 VanDerWaalsContact O-CB 3.25Å; K99-A103 WeakPolarHBondContact O-CB 3.31Å; K99-A103 PolarHBondContact O-N 3.48Å; L100-A103 PolarHBondContact O-N 3.4Å; V101-A103 PolarHBondContact O-N 3.26Å; A103-R107 VanDerWaalsContact O-CB 3.25Å; A103-R107 WeakPolarHBondContact O-CB 3.36Å; A103-R107 PolarHBondContact O-N 3.39Å; A103-V276 HydrophobicContact CB-CB 4.48Å; A103-V276 HydrophobicContact CB-CG1 3.9Å; A103-V276 HydrophobicContact CB-CG2 4.31Å; A103-L279 HydrophobicContact CB-CB 4.28Å; A103-L279 HydrophobicContact CB-CD1 3.81Å; A103-M280 HydrophobicContact CB-CG 3.99Å; A103-M280 HydrophobicContact CB-SD 3.84Å
104V96.7Very high93.3Very high0 Ų041.6 Ų41.60%021%0.208CC..Hα-helixtrans-65.7-48.7176.6171.40000110.4I81 I83 L100 V101 Q106 R107 E108 V113 I161 L279I81-V104 HydrophobicContact CB-CG1 4.39Å; I81-V104 HydrophobicContact CD1-CG1 3.71Å; I81-V104 HydrophobicContact CG2-CG1 4.06Å; I83-V104 HydrophobicContact CD1-CB 4.46Å; I83-V104 HydrophobicContact CD1-CG2 4.26Å; L100-V104 HydrophobicContact CD1-CG2 4.03Å; L100-V104 HydrophobicContact CG-CG2 4.47Å; L100-V104 WeakPolarHBondContact O-CG2 3.48Å; L100-V104 PolarHBondContact O-N 3.47Å; V101-V104 PolarHBondContact O-N 3.26Å; V104-Q106 VanDerWaalsContact C-N 3.34Å; V104-Q106 PolarHBondContact O-N 3.05Å; V104-R107 PolarHBondContact O-N 3.07Å; V104-R107 VanDerWaalsContact O-N 3.14Å; V104-E108 PolarHBondContact O-N 3.33Å; V104-V113 HydrophobicContact CG1-CG1 4.22Å; V104-V113 HydrophobicContact CG1-CG2 3.82Å; V104-I161 HydrophobicContact CG2-CD1 4.16Å; V104-L279 HydrophobicContact CG2-CD1 3.65Å
105M94.7Very high94Very high30 Ų3040.4 Ų40.415%0.14820%0.203CC..Hα-helixtrans-63.6-37.2178.7-70.8-179.274.700112.5R49 L52 V101 S102 R107 E108 N109 V113R49-M105 HydrophobicContact CB-CE 4.1Å; R49-M105 HydrophobicContact CB-SD 3.65Å; L52-M105 HydrophobicContact CD2-CB 3.64Å; L52-M105 HydrophobicContact CD2-SD 4.19Å; V101-M105 HydrophobicContact CG1-CG 4.26Å; V101-M105 HydrophobicContact CG1-SD 3.79Å; V101-M105 WeakPolarHBondContact O-CB 3.46Å; V101-M105 WeakPolarHBondContact O-CG 3.45Å; V101-M105 PolarHBondContact O-N 3.25Å; S102-M105 PolarHBondContact O-N 2.98Å; M105-R107 VanDerWaalsContact C-N 3.32Å; M105-E108 CarbonylContact O-C 3.55Å; M105-N109 VanDerWaalsContact O-CA 3.27Å; M105-N109 WeakPolarHBondContact O-CA 3.43Å; M105-N109 PolarHBondContact O-N 3.33Å; M105-V113 HydrophobicContact CG-CB 3.97Å; M105-V113 HydrophobicContact CG-CG1 4.14Å; M105-V113 HydrophobicContact CG-CG2 3.78Å
106Q94.3Very high94.5Very high103 Ų10335.9 Ų35.948%0.48118%0.175SC..Hα-helixtrans-68.4-34.3174.7-74.9176.856.800112L52 S102 V104 M280L52-Q106 HydrophobicContact CD1-CG 4.3Å; L52-Q106 HydrophobicContact CD2-CG 4.11Å; S102-Q106 WeakPolarHBondContact O-CB 3.21Å; S102-Q106 WeakPolarHBondContact O-CG 3.35Å; S102-Q106 PolarHBondContact O-N 3.24Å; S102-Q106 PolarHBondContact O-NE2 2.91Å; S102-Q106 PolarHBondContact OG-NE2 3.04Å; V104-Q106 VanDerWaalsContact C-N 3.34Å; V104-Q106 PolarHBondContact O-N 3.05Å; Q106-M280 HydrophobicContact CB-SD 4.46Å
107R94.2Very high94.9Very high57 Ų5737 Ų3722%0.21518%0.181CC..Hα-helixtrans-77.8-40.2-180179.855.8-177.5-120.5-1.5112.8A103 V104 M105 L279 K282 Y315 N316A103-R107 VanDerWaalsContact O-CB 3.25Å; A103-R107 WeakPolarHBondContact O-CB 3.36Å; A103-R107 PolarHBondContact O-N 3.39Å; V104-R107 PolarHBondContact O-N 3.07Å; V104-R107 VanDerWaalsContact O-N 3.14Å; M105-R107 VanDerWaalsContact C-N 3.32Å; R107-L279 HydrophobicContact CB-CB 4.35Å; R107-L279 HydrophobicContact CB-CD2 3.84Å; R107-L279 HydrophobicContact CG-CD2 3.69Å; R107-L279 PolarHBondContact NH1-O 3.45Å; R107-L279 VanDerWaalsContact NH1-O 3.09Å; R107-K282 VanDerWaalsContact CZ-CE 3.42Å; R107-Y315 HydrophobicContact CG-CD1 4.33Å; R107-Y315 HydrophobicContact CG-CE1 4.24Å; R107-N316 PolarHBondContact NH2-OD1 3.22Å
108E94.8Very high95.2Very high36 Ų3637 Ų3717%0.16818%0.181CC..SBendtrans-123.572-176.3-59.2-69.1148.900108.5K79 I81 V104 M105 E110 A111 Y315K79-E108 WeakPolarHBondContact CD-OE2 3.18Å; K79-E108 IonicContact NZ-OE1 3.74Å; K79-E108 PolarHBondContact NZ-OE1 3.32Å; K79-E108 VanDerWaalsContact NZ-OE1 3.14Å; K79-E108 IonicContact NZ-OE2 2.92Å; K79-E108 PolarHBondContact NZ-OE2 2.84Å; I81-E108 HydrophobicContact CD1-CB 4.25Å; I81-E108 HydrophobicContact CD1-CG 4.09Å; V104-E108 PolarHBondContact O-N 3.33Å; M105-E108 CarbonylContact O-C 3.55Å; E108-E110 PolarHBondContact O-N 3.16Å; E108-A111 HydrophobicContact CB-CB 3.7Å; E108-A111 WeakPolarHBondContact O-CB 3.3Å; E108-A111 PolarHBondContact O-N 3.34Å; E108-A111 VanDerWaalsContact O-N 3.11Å; E108-Y315 HydrophobicContact CG-CE1 4.41Å; E108-Y315 WeakPolarHBondContact CG-OH 3.37Å; E108-Y315 VanDerWaalsContact OE1-CE1 3.22Å; E108-Y315 WeakPolarHBondContact OE1-CE1 3.48Å; E108-Y315 PolarHBondContact OE1-OH 3.44Å
109N91.9Very high95.4Very high133 Ų13334.3 Ų34.371%0.71117%0.169SC*.THydrogen-bonded Turntrans-63.4-19.6-173.762.9-25.9000114.8M105M105-N109 VanDerWaalsContact O-CA 3.27Å; M105-N109 WeakPolarHBondContact O-CA 3.43Å; M105-N109 PolarHBondContact O-N 3.33Å
110E93.9Very high95.5Very high148 Ų14831.6 Ų31.669%0.69216%0.162SC*.THydrogen-bonded Turntrans-101.6-2.3178.3-66176.9-178.500113S78 E108S78-E110 WeakPolarHBondContact CB-O 3.43Å; S78-E110 PolarHBondContact OG-O 3.42Å; E108-E110 PolarHBondContact O-N 3.16Å
111A96.9Very high95.5Very high17 Ų1731.6 Ų31.614%0.1416%0.163CC..SBendtrans-78.8149.5-176.600000112.5K79 I81 E108 V113K79-A111 HydrophobicContact CB-CB 4.08Å; K79-A111 CarbonylContact O-C 3.49Å; K79-A111 VanDerWaalsContact O-CA 3.24Å; K79-A111 WeakPolarHBondContact O-CA 3.32Å; K79-A111 WeakPolarHBondContact O-CB 3.43Å; I81-A111 HydrophobicContact CD1-CB 4.16Å; I81-A111 HydrophobicContact CG1-CB 4.42Å; E108-A111 HydrophobicContact CB-CB 3.7Å; E108-A111 WeakPolarHBondContact O-CB 3.3Å; E108-A111 PolarHBondContact O-N 3.34Å; E108-A111 VanDerWaalsContact O-N 3.11Å; A111-V113 HydrophobicContact CB-CG2 4.36Å; A111-V113 PolarHBondContact O-N 3.1Å
112N97.5Very high95.4Very high4 Ų431.6 Ų31.62%0.02116%0.163CC..EExtended strand (participates in β ladder)trans-76.8103.6165.5-46.7-63.4000108.1M48 F74 N75 K79 T80 I81M48-N112 HydrophobicContact CE-CB 3.94Å; M48-N112 VanDerWaalsContact CE-OD1 3.32Å; M48-N112 WeakPolarHBondContact CE-OD1 3.4Å; M48-N112 HydrophobicContact SD-CB 4.43Å; F74-N112 HydrophobicContact CD2-CB 3.95Å; F74-N112 HydrophobicContact CE2-CB 3.78Å; N75-N112 PolarHBondContact N-OD1 2.93Å; N75-N112 PolarHBondContact O-ND2 2.91Å; K79-N112 PolarHBondContact O-N 2.88Å; T80-N112 HydrophobicContact CG2-CB 4.32Å; T80-N112 PolarHBondContact OG1-ND2 3.2Å; I81-N112 PolarHBondContact N-O 2.85Å
113V97.6Very high95.4Very high2 Ų234.5 Ų34.51%0.01217%0.173CC..EExtended strand (participates in β ladder)trans-97.6116177.7-1770000109.3M48 R49 I81 I83 V101 V104 M105 A111M48-V113 WeakPolarHBondContact CA-O 3.34Å; R49-V113 PolarHBondContact N-O 3.42Å; I81-V113 WeakPolarHBondContact O-CA 3.48Å; I83-V113 HydrophobicContact CD1-CG1 3.97Å; V101-V113 HydrophobicContact CG1-CG1 4.31Å; V104-V113 HydrophobicContact CG1-CG1 4.22Å; V104-V113 HydrophobicContact CG1-CG2 3.82Å; M105-V113 HydrophobicContact CG-CB 3.97Å; M105-V113 HydrophobicContact CG-CG1 4.14Å; M105-V113 HydrophobicContact CG-CG2 3.78Å; A111-V113 HydrophobicContact CB-CG2 4.36Å; A111-V113 PolarHBondContact O-N 3.1Å
114V97.7Very high95.2Very high0 Ų037.7 Ų37.70%019%0.187CC..EExtended strand (participates in β ladder)trans-118.3125.8-175.4-174.40000109.7Y46 N47 M48 L61 I81 F82 I83Y46-V114 HydrophobicContact CD1-CG1 4.44Å; N47-V114 WeakPolarHBondContact O-CA 3.48Å; M48-V114 HydrophobicContact CB-CG2 4.15Å; M48-V114 HydrophobicContact CG-CG2 4.28Å; L61-V114 HydrophobicContact CD1-CG1 4.45Å; L61-V114 HydrophobicContact CD1-CG2 3.88Å; I81-V114 PolarHBondContact O-N 2.81Å; F82-V114 CarbonylContact C-O 3.48Å; F82-V114 VanDerWaalsContact CA-O 3.31Å; F82-V114 WeakPolarHBondContact CA-O 3.45Å; F82-V114 HydrophobicContact CD1-CB 3.63Å; F82-V114 HydrophobicContact CD1-CG1 4.35Å; F82-V114 HydrophobicContact CD1-CG2 3.9Å; F82-V114 HydrophobicContact CD2-CB 4.49Å; F82-V114 HydrophobicContact CD2-CG1 4.44Å; F82-V114 HydrophobicContact CE1-CB 3.61Å; F82-V114 HydrophobicContact CE1-CG1 4.1Å; F82-V114 HydrophobicContact CE1-CG2 3.48Å; F82-V114 VanDerWaalsContact CE1-CG2 3.48Å; F82-V114 HydrophobicContact CE2-CB 4.5Å; F82-V114 HydrophobicContact CE2-CG1 4.21Å; F82-V114 HydrophobicContact CG-CB 4.08Å; F82-V114 HydrophobicContact CZ-CB 4.07Å; F82-V114 HydrophobicContact CZ-CG1 4.03Å; F82-V114 HydrophobicContact CZ-CG2 4.08Å; I83-V114 PolarHBondContact N-O 2.54Å
115V97Very high95Very high6 Ų643.1 Ų43.14%0.03622%0.216CC..EExtended strand (participates in β ladder)trans-90.8122.4169.6175.10000108.4N47 R49 F93 M97 V101N47-V115 HydrophobicContact CB-CB 4.41Å; N47-V115 PolarHBondContact N-O 2.99Å; N47-V115 PolarHBondContact O-N 3.36Å; R49-V115 HydrophobicContact CG-CG2 3.96Å; F93-V115 HydrophobicContact CZ-CG1 4.25Å; M97-V115 HydrophobicContact CE-CB 3.97Å; M97-V115 HydrophobicContact CE-CG1 3.45Å; M97-V115 VanDerWaalsContact CE-CG1 3.45Å; M97-V115 HydrophobicContact CE-CG2 3.42Å; M97-V115 VanDerWaalsContact CE-CG2 3.42Å; V101-V115 HydrophobicContact CG2-CG2 3.67Å
116V97.5Very high94.8Very high0 Ų043.3 Ų43.30%022%0.215CC..EExtended strand (participates in β ladder)trans-89.4106.2174.4-174.70000108.4I44 Y46 F82 I83 I84 H85 I140I44-V116 HydrophobicContact CG2-CG1 3.82Å; Y46-V116 HydrophobicContact CD1-CG2 4.15Å; Y46-V116 HydrophobicContact CE1-CG1 4.25Å; Y46-V116 HydrophobicContact CE1-CG2 4.25Å; F82-V116 HydrophobicContact CB-CG2 4.23Å; F82-V116 HydrophobicContact CD2-CG2 3.55Å; F82-V116 HydrophobicContact CE2-CG2 4.31Å; F82-V116 HydrophobicContact CG-CG2 4.24Å; I83-V116 PolarHBondContact O-N 3.24Å; I84-V116 HydrophobicContact CG1-CB 4.13Å; I84-V116 HydrophobicContact CG1-CG2 3.94Å; H85-V116 PolarHBondContact CD2-O 2.93Å; V116-I140 HydrophobicContact CG1-CD1 3.95Å; V116-I140 HydrophobicContact CG1-CG1 4.2Å; V116-I140 HydrophobicContact CG2-CD1 4.43Å
117D95.7Very high94.7Very high29 Ų2941 Ų4116%0.15521%0.209CC..EExtended strand (participates in β ladder)trans-92.4105.1175.9177.17.9000109.4I44 K45 F93 M119I44-D117 CarbonylContact C-O 3.58Å; I44-D117 WeakPolarHBondContact CA-O 3.41Å; K45-D117 HydrophobicContact CB-CB 4.17Å; K45-D117 PolarHBondContact N-O 2.87Å; K45-D117 PolarHBondContact O-N 2.72Å; F93-D117 HydrophobicContact CZ-CB 3.89Å; D117-M119 WeakPolarHBondContact OD1-CB 3.3Å; D117-M119 PolarHBondContact OD1-N 3.27Å
118W96.8Very high94.7Very high0 Ų041.3 Ų41.30%022%0.215CC..  trans-116.225.9171.567.8-71.4000110.8I44 H85 P120 L121 A122 T133 V136 L165 V169I44-W118 HydrophobicContact CG1-CB 4.24Å; H85-W118 AromaticContact CD2-CD1 3.63Å; H85-W118 AromaticContact CD2-NE1 3.78Å; H85-W118 AromaticContact CE1-CD1 3.41Å; H85-W118 VanDerWaalsContact CE1-CD1 3.41Å; H85-W118 AromaticContact CE1-CE2 3.87Å; H85-W118 AromaticContact CE1-CG 3.92Å; H85-W118 AromaticContact CE1-NE1 3.36Å; H85-W118 PolarHBondContact CE1-NE1 2.88Å; H85-W118 AromaticContact CG-NE1 3.79Å; H85-W118 AromaticContact ND1-CD1 3.98Å; H85-W118 AromaticContact ND1-NE1 3.52Å; H85-W118 AromaticContact NE2-CD1 3.17Å; H85-W118 AromaticContact NE2-CG 3.84Å; H85-W118 PolarHBondContact NE2-N 3.15Å; H85-W118 VanDerWaalsContact NE2-N 3.15Å; H85-W118 AromaticContact NE2-NE1 3.55Å; H85-W118 WeakPolarHBondContact O-CZ2 3.39Å; H85-W118 PolarHBondContact O-NE1 2.92Å; W118-P120 VanDerWaalsContact C-N 3.33Å; W118-L121 HydrophobicContact CE3-CB 3.76Å; W118-L121 HydrophobicContact CZ3-CB 4.37Å; W118-L121 WeakPolarHBondContact O-CB 3.49Å; W118-L121 PolarHBondContact O-N 2.97Å; W118-A122 HydrophobicContact CD2-CB 3.79Å; W118-A122 HydrophobicContact CE3-CB 3.71Å; W118-A122 HydrophobicContact CH2-CB 3.69Å; W118-A122 HydrophobicContact CZ2-CB 3.77Å; W118-A122 VanDerWaalsContact CZ3-CA 3.48Å; W118-A122 HydrophobicContact CZ3-CB 3.66Å; W118-A122 PolarHBondContact O-N 3.15Å; W118-T133 HydrophobicContact CH2-CG2 4.34Å; W118-V136 HydrophobicContact CB-CG1 3.94Å; W118-V136 HydrophobicContact CB-CG2 4.11Å; W118-V136 HydrophobicContact CD2-CG1 4.34Å; W118-V136 HydrophobicContact CD2-CG2 4.18Å; W118-V136 HydrophobicContact CE3-CG2 3.76Å; W118-V136 HydrophobicContact CG-CG1 4Å; W118-V136 HydrophobicContact CG-CG2 4.35Å; W118-L165 HydrophobicContact CH2-CB 3.95Å; W118-L165 HydrophobicContact CH2-CD1 3.93Å; W118-L165 HydrophobicContact CZ2-CB 4.02Å; W118-V169 HydrophobicContact CZ2-CG2 4.4Å
119M94.3Very high94.7Very high17 Ų1739.6 Ų39.68%0.08421%0.207CC..Hα-helixtrans-48-42.9-176.7-166.670.667.500114.2T88 G91 F93 D117 L121 A122 Q123T88-M119 HydrophobicContact CG2-CE 4.24Å; T88-M119 HydrophobicContact CG2-SD 3.24Å; T88-M119 WeakPolarHBondContact CG2-SD 3.29Å; G91-M119 VanDerWaalsContact C-SD 3.51Å; G91-M119 WeakPolarHBondContact O-CG 3.4Å; F93-M119 HydrophobicContact CD1-CE 3.55Å; F93-M119 HydrophobicContact CE1-CE 3.57Å; F93-M119 HydrophobicContact CG-CE 4.15Å; F93-M119 HydrophobicContact CZ-CE 4.21Å; D117-M119 WeakPolarHBondContact OD1-CB 3.3Å; D117-M119 PolarHBondContact OD1-N 3.27Å; M119-L121 PolarHBondContact O-N 3.43Å; M119-L121 VanDerWaalsContact O-N 3.1Å; M119-A122 PolarHBondContact O-N 3.02Å; M119-Q123 VanDerWaalsContact O-CB 3.31Å; M119-Q123 WeakPolarHBondContact O-CB 3.25Å; M119-Q123 PolarHBondContact O-N 3.38Å
120P93.9Very high94.9Very high51 Ų5133.8 Ų33.833%0.33118%0.176SC..Hα-helixtrans-61.3-23.3179.7-23.835.6000114.3W118 Q124W118-P120 VanDerWaalsContact C-N 3.33Å; P120-Q124 PolarHBondContact O-NE2 3.25Å
121L95.4Very high95Very high1 Ų131.8 Ų31.81%0.00517%0.171CC..Hα-helixtrans-99.7-28.7-179.7-62.9174.8000111.7V40 I44 W118 M119 Q124 H132 V136V40-L121 HydrophobicContact CG1-CD1 4.03Å; V40-L121 HydrophobicContact CG2-CD1 4.25Å; I44-L121 HydrophobicContact CG1-CD1 4.26Å; W118-L121 HydrophobicContact CE3-CB 3.76Å; W118-L121 HydrophobicContact CZ3-CB 4.37Å; W118-L121 WeakPolarHBondContact O-CB 3.49Å; W118-L121 PolarHBondContact O-N 2.97Å; M119-L121 PolarHBondContact O-N 3.43Å; M119-L121 VanDerWaalsContact O-N 3.1Å; L121-Q124 WeakPolarHBondContact O-CG 3.33Å; L121-H132 HydrophobicContact CB-CB 4.03Å; L121-H132 PolarHBondContact O-ND1 3.04Å; L121-H132 VanDerWaalsContact O-ND1 3.13Å; L121-V136 HydrophobicContact CD1-CG2 3.66Å
122A94.2Very high95Very high0 Ų033.4 Ų33.40%018%0.175CC..Hα-helixtrans-77.8-29.7175.700000113.3W118 M119 Q124W118-A122 HydrophobicContact CD2-CB 3.79Å; W118-A122 HydrophobicContact CE3-CB 3.71Å; W118-A122 HydrophobicContact CH2-CB 3.69Å; W118-A122 HydrophobicContact CZ2-CB 3.77Å; W118-A122 VanDerWaalsContact CZ3-CA 3.48Å; W118-A122 HydrophobicContact CZ3-CB 3.66Å; W118-A122 PolarHBondContact O-N 3.15Å; M119-A122 PolarHBondContact O-N 3.02Å; A122-Q124 PolarHBondContact O-N 3.4Å; A122-Q124 VanDerWaalsContact O-N 3.12Å
123Q93.4Very high95Very high87 Ų8733.4 Ų33.441%0.40718%0.175SC..SBendtrans-87.351.8179.4-163.9-161.8-10.100112T88 M119T88-Q123 VanDerWaalsContact O-CA 3.28Å; T88-Q123 WeakPolarHBondContact O-CA 3.33Å; T88-Q123 WeakPolarHBondContact O-CG 3.38Å; M119-Q123 VanDerWaalsContact O-CB 3.31Å; M119-Q123 WeakPolarHBondContact O-CB 3.25Å; M119-Q123 PolarHBondContact O-N 3.38Å
124Q91.8Very high95Very high70 Ų7036.2 Ų36.233%0.32719%0.19SC..SBendtrans-120.8176.9177.3-59.6-61.8-27.200109.8W87 P120 L121 A122 D128 A129W87-Q124 PolarHBondContact NE1-O 3.23Å; P120-Q124 PolarHBondContact O-NE2 3.25Å; L121-Q124 WeakPolarHBondContact O-CG 3.33Å; A122-Q124 PolarHBondContact O-N 3.4Å; A122-Q124 VanDerWaalsContact O-N 3.12Å; Q124-D128 HydrophobicContact CB-CB 3.86Å; Q124-A129 HydrophobicContact CB-CB 4.44Å
125L90.8Very high95Very high115 Ų11537.4 Ų37.460%0.60220%0.199SC*.  trans-56.3146.2165.7-62.9175.5000108.8D128 A129L125-D128 WeakPolarHBondContact O-CB 3.4Å; L125-D128 PolarHBondContact O-N 2.63Å; L125-A129 PolarHBondContact O-N 3.39Å
126Y90.5Very high95.1Very high33 Ų3337.1 Ų37.113%0.12920%0.198CC..Hα-helixtrans-53.3-46.1-170.8-179.2-91.6000113.7W87 D128 A129 V130 L165 P192 M193W87-Y126 HydrophobicContact CD2-CD2 4.13Å; W87-Y126 HydrophobicContact CG-CD2 4.11Å; Y126-D128 VanDerWaalsContact C-N 3.33Å; Y126-D128 PolarHBondContact O-N 3.42Å; Y126-A129 PolarHBondContact O-N 2.99Å; Y126-V130 HydrophobicContact CD1-CG2 3.99Å; Y126-V130 HydrophobicContact CE1-CG2 3.52Å; Y126-V130 HydrophobicContact CE2-CG2 4.36Å; Y126-V130 WeakPolarHBondContact O-CG2 3.43Å; Y126-V130 PolarHBondContact O-N 2.75Å; Y126-L165 HydrophobicContact CE2-CD2 4.24Å; Y126-L165 HydrophobicContact CE2-CG 4.5Å; Y126-P192 HydrophobicContact CE1-CB 3.71Å; Y126-P192 HydrophobicContact CE1-CG 4.41Å; Y126-P192 WeakPolarHBondContact OH-CD 3.05Å; Y126-P192 PolarHBondContact OH-O 3.09Å; Y126-M193 HydrophobicContact CD1-SD 4.47Å; Y126-M193 HydrophobicContact CE1-SD 4.35Å
127P94.1Very high95.1Very high54 Ų5437.1 Ų37.135%0.35120%0.198SC..Hα-helixtrans-61.2-37.5176.4-23.835.8000113.8V130 N131 M193P127-V130 WeakPolarHBondContact O-CB 3.34Å; P127-V130 PolarHBondContact O-N 3.24Å; P127-N131 VanDerWaalsContact O-CG 3.28Å; P127-N131 PolarHBondContact O-N 3.09Å; P127-N131 PolarHBondContact O-ND2 2.98Å; P127-M193 HydrophobicContact CB-CE 4.31Å; P127-M193 HydrophobicContact CB-SD 4.02Å; P127-M193 HydrophobicContact CG-SD 4.35Å
128D93.8Very high95.2Very high65 Ų6537 Ų3735%0.34820%0.198SC..Hα-helixtrans-67.5-43.2177.6-58.3-31.2000110.5Q124 L125 Y126 V130 N131 H132Q124-D128 HydrophobicContact CB-CB 3.86Å; L125-D128 WeakPolarHBondContact O-CB 3.4Å; L125-D128 PolarHBondContact O-N 2.63Å; Y126-D128 VanDerWaalsContact C-N 3.33Å; Y126-D128 PolarHBondContact O-N 3.42Å; D128-V130 VanDerWaalsContact C-N 3.3Å; D128-V130 PolarHBondContact O-N 3.36Å; D128-N131 PolarHBondContact O-N 3.14Å; D128-H132 VanDerWaalsContact O-CG 3.28Å; D128-H132 PolarHBondContact O-N 3.43Å; D128-H132 PolarHBondContact O-ND1 3.45Å; D128-H132 VanDerWaalsContact O-ND1 3.13Å
129A95.2Very high95.3Very high0 Ų038.3 Ų38.30%021%0.205CC..Hα-helixtrans-62.9-37.1175.100000112.2Q124 L125 Y126 H132 T133 L165Q124-A129 HydrophobicContact CB-CB 4.44Å; L125-A129 PolarHBondContact O-N 3.39Å; Y126-A129 PolarHBondContact O-N 2.99Å; A129-H132 PolarHBondContact O-N 2.8Å; A129-T133 WeakPolarHBondContact O-CG2 3.44Å; A129-T133 PolarHBondContact O-N 2.89Å; A129-L165 HydrophobicContact CB-CD1 3.84Å
130V95.5Very high95.5Very high10 Ų1037.5 Ų37.56%0.06120%0.201CC..Hα-helixtrans-60.2-49.3171.31680000110.4Y126 P127 D128 H132 T133 L165 M193 F194Y126-V130 HydrophobicContact CD1-CG2 3.99Å; Y126-V130 HydrophobicContact CE1-CG2 3.52Å; Y126-V130 HydrophobicContact CE2-CG2 4.36Å; Y126-V130 WeakPolarHBondContact O-CG2 3.43Å; Y126-V130 PolarHBondContact O-N 2.75Å; P127-V130 WeakPolarHBondContact O-CB 3.34Å; P127-V130 PolarHBondContact O-N 3.24Å; D128-V130 VanDerWaalsContact C-N 3.3Å; D128-V130 PolarHBondContact O-N 3.36Å; V130-H132 PolarHBondContact O-N 2.71Å; V130-T133 WeakPolarHBondContact O-CB 3.33Å; V130-T133 WeakPolarHBondContact O-CG2 3.25Å; V130-T133 PolarHBondContact O-N 3.02Å; V130-T133 PolarHBondContact O-OG1 3.2Å; V130-L165 HydrophobicContact CG2-CD1 4.49Å; V130-L165 HydrophobicContact CG2-CD2 3.84Å; V130-M193 HydrophobicContact CB-CE 4.5Å; V130-M193 HydrophobicContact CB-SD 4.14Å; V130-M193 HydrophobicContact CG1-CB 4Å; V130-M193 HydrophobicContact CG1-CE 4.07Å; V130-M193 HydrophobicContact CG1-SD 4.1Å; V130-M193 HydrophobicContact CG2-CB 4.46Å; V130-M193 HydrophobicContact CG2-SD 4.06Å; V130-F194 HydrophobicContact CG1-CE2 3.98Å; V130-F194 HydrophobicContact CG1-CZ 3.88Å; V130-F194 HydrophobicContact CG2-CE2 4.07Å
131N95.3Very high95.7Very high107 Ų10735.2 Ų35.257%0.57219%0.186SC*.Hα-helixtrans-61.3-32.2-179.9-69.9-19.7000112.6P127 D128 T133P127-N131 VanDerWaalsContact O-CG 3.28Å; P127-N131 PolarHBondContact O-N 3.09Å; P127-N131 PolarHBondContact O-ND2 2.98Å; D128-N131 PolarHBondContact O-N 3.14Å; N131-T133 VanDerWaalsContact C-N 3.3Å; N131-T133 PolarHBondContact O-N 3.07Å
132H97.1Very high95.8Very high51 Ų5140 Ų4024%0.23621%0.207CC..Hα-helixtrans-71.4-18.7175.5-62.5143.3000114.2L121 D128 A129 V130 L134 A135 V136L121-H132 HydrophobicContact CB-CB 4.03Å; L121-H132 PolarHBondContact O-ND1 3.04Å; L121-H132 VanDerWaalsContact O-ND1 3.13Å; D128-H132 VanDerWaalsContact O-CG 3.28Å; D128-H132 PolarHBondContact O-N 3.43Å; D128-H132 PolarHBondContact O-ND1 3.45Å; D128-H132 VanDerWaalsContact O-ND1 3.13Å; A129-H132 PolarHBondContact O-N 2.8Å; V130-H132 PolarHBondContact O-N 2.71Å; H132-L134 VanDerWaalsContact C-N 3.3Å; H132-L134 PolarHBondContact O-N 2.91Å; H132-A135 PolarHBondContact O-N 3.01Å; H132-V136 VanDerWaalsContact O-CG2 3.29Å; H132-V136 WeakPolarHBondContact O-CG2 3.47Å; H132-V136 PolarHBondContact O-N 3.15Å
133T98.2Very high96Very high4 Ų440 Ų403%0.02521%0.207CC..Hα-helixtrans-59.6-38.6-17457.40000113.4W118 A129 V130 N131 G137 L165 V169 F172 F194W118-T133 HydrophobicContact CH2-CG2 4.34Å; A129-T133 WeakPolarHBondContact O-CG2 3.44Å; A129-T133 PolarHBondContact O-N 2.89Å; V130-T133 WeakPolarHBondContact O-CB 3.33Å; V130-T133 WeakPolarHBondContact O-CG2 3.25Å; V130-T133 PolarHBondContact O-N 3.02Å; V130-T133 PolarHBondContact O-OG1 3.2Å; N131-T133 VanDerWaalsContact C-N 3.3Å; N131-T133 PolarHBondContact O-N 3.07Å; T133-G137 PolarHBondContact O-N 3.33Å; T133-L165 HydrophobicContact CG2-CB 4.04Å; T133-L165 HydrophobicContact CG2-CD1 4.34Å; T133-L165 HydrophobicContact CG2-CD2 4.28Å; T133-L165 HydrophobicContact CG2-CG 4.47Å; T133-V169 HydrophobicContact CG2-CG2 3.87Å; T133-F172 WeakPolarHBondContact OG1-CE2 3.27Å; T133-F194 HydrophobicContact CG2-CZ 4.34Å
134L97.5Very high96.2Very high60 Ų6035.9 Ų35.931%0.31419%0.188SC..Hα-helixtrans-61.8-51.6175.8173.461.1000111H132 V136 G137 V138 F172 Y176H132-L134 VanDerWaalsContact C-N 3.3Å; H132-L134 PolarHBondContact O-N 2.91Å; L134-V136 VanDerWaalsContact C-N 3.31Å; L134-V136 PolarHBondContact O-N 3.36Å; L134-G137 PolarHBondContact O-N 3.02Å; L134-G137 VanDerWaalsContact O-N 3.14Å; L134-V138 HydrophobicContact CD1-CG2 4.14Å; L134-V138 WeakPolarHBondContact O-CG2 3.3Å; L134-V138 PolarHBondContact O-N 3.12Å; L134-F172 HydrophobicContact CB-CD2 4.38Å; L134-F172 HydrophobicContact CB-CE1 4.48Å; L134-F172 HydrophobicContact CB-CE2 4.28Å; L134-F172 HydrophobicContact CB-CZ 4.32Å; L134-F172 HydrophobicContact CD1-CB 4.47Å; L134-F172 HydrophobicContact CD1-CD1 3.57Å; L134-F172 HydrophobicContact CD1-CE1 3.84Å; L134-F172 HydrophobicContact CD1-CG 4.01Å; L134-F172 HydrophobicContact CD1-CZ 4.5Å; L134-Y176 HydrophobicContact CD1-CD2 4.32Å; L134-Y176 HydrophobicContact CD1-CE2 3.45Å; L134-Y176 VanDerWaalsContact CD1-CE2 3.45Å
135A97.4Very high96.5Very high25 Ų2533.5 Ų33.521%0.20718%0.177CC..Hα-helixtrans-64.6-36.5-176.600000112.1V40 H132 D139V40-A135 HydrophobicContact CG2-CB 3.69Å; H132-A135 PolarHBondContact O-N 3.01Å; A135-D139 PolarHBondContact O-N 2.84Å; A135-D139 VanDerWaalsContact O-N 3.07Å
136V98.4Very high96.8Very high0 Ų029 Ų290%015%0.152CC..Hα-helixtrans-65.2-44.6172.4-179.90000111I44 W118 L121 H132 L134 V138 D139 I140 V169I44-V136 HydrophobicContact CD1-CB 4.09Å; I44-V136 HydrophobicContact CD1-CG1 3.9Å; I44-V136 HydrophobicContact CD1-CG2 3.98Å; I44-V136 HydrophobicContact CG1-CG1 4.49Å; I44-V136 HydrophobicContact CG1-CG2 4.48Å; W118-V136 HydrophobicContact CB-CG1 3.94Å; W118-V136 HydrophobicContact CB-CG2 4.11Å; W118-V136 HydrophobicContact CD2-CG1 4.34Å; W118-V136 HydrophobicContact CD2-CG2 4.18Å; W118-V136 HydrophobicContact CE3-CG2 3.76Å; W118-V136 HydrophobicContact CG-CG1 4Å; W118-V136 HydrophobicContact CG-CG2 4.35Å; L121-V136 HydrophobicContact CD1-CG2 3.66Å; H132-V136 VanDerWaalsContact O-CG2 3.29Å; H132-V136 WeakPolarHBondContact O-CG2 3.47Å; H132-V136 PolarHBondContact O-N 3.15Å; L134-V136 VanDerWaalsContact C-N 3.31Å; L134-V136 PolarHBondContact O-N 3.36Å; V136-V138 VanDerWaalsContact C-N 3.35Å; V136-V138 PolarHBondContact O-N 2.85Å; V136-D139 PolarHBondContact O-N 2.76Å; V136-I140 HydrophobicContact CG1-CD1 4.14Å; V136-I140 WeakPolarHBondContact O-CG1 3.49Å; V136-I140 PolarHBondContact O-N 3.04Å; V136-V169 HydrophobicContact CB-CG1 4.04Å; V136-V169 HydrophobicContact CB-CG2 4.29Å; V136-V169 HydrophobicContact CG1-CG1 3.51Å; V136-V169 HydrophobicContact CG1-CG2 4.31Å
137G98.4Very high97.1Very high0 Ų027.4 Ų27.40%015%0.146CC..Hα-helixtrans-60.4-43.1176.800000112.7T133 L134 D139 I140 A141 V169 A173T133-G137 PolarHBondContact O-N 3.33Å; L134-G137 PolarHBondContact O-N 3.02Å; L134-G137 VanDerWaalsContact O-N 3.14Å; G137-D139 VanDerWaalsContact C-N 3.34Å; G137-D139 PolarHBondContact O-N 3.49Å; G137-I140 PolarHBondContact O-N 3.1Å; G137-A141 PolarHBondContact O-N 3.34Å; G137-V169 WeakPolarHBondContact CA-O 3.34Å; G137-A173 VanDerWaalsContact O-CA 3.29Å; G137-A173 WeakPolarHBondContact O-CA 3.24Å; G137-A173 WeakPolarHBondContact O-CB 3.49Å
138V98.1Very high97.2Very high27 Ų2727.1 Ų27.116%0.16414%0.14CC..Hα-helixtrans-62.3-38.6175.4171.20000111.9L134 V136 A141 K142 Y176L134-V138 HydrophobicContact CD1-CG2 4.14Å; L134-V138 WeakPolarHBondContact O-CG2 3.3Å; L134-V138 PolarHBondContact O-N 3.12Å; V136-V138 VanDerWaalsContact C-N 3.35Å; V136-V138 PolarHBondContact O-N 2.85Å; V138-A141 PolarHBondContact O-N 2.96Å; V138-K142 WeakPolarHBondContact O-CG 3.11Å; V138-K142 PolarHBondContact O-N 2.91Å; V138-Y176 HydrophobicContact CG2-CD1 4.21Å; V138-Y176 HydrophobicContact CG2-CD2 3.75Å; V138-Y176 HydrophobicContact CG2-CE1 4.45Å; V138-Y176 HydrophobicContact CG2-CE2 4.05Å; V138-Y176 HydrophobicContact CG2-CG 3.85Å
139D97.9Very high97.3Very high28 Ų2829.3 Ų29.315%0.1515%0.148CC..Hα-helixtrans-65.2-42.1175.6-169.1-102.6000111.9I44 Y46 A135 V136 G137 A141 K142 M143I44-D139 HydrophobicContact CD1-CB 3.55Å; Y46-D139 WeakPolarHBondContact CE2-OD1 3.42Å; Y46-D139 VanDerWaalsContact OH-C 3.31Å; Y46-D139 PolarHBondContact OH-O 2.96Å; Y46-D139 PolarHBondContact OH-OD1 2.87Å; A135-D139 PolarHBondContact O-N 2.84Å; A135-D139 VanDerWaalsContact O-N 3.07Å; V136-D139 PolarHBondContact O-N 2.76Å; G137-D139 VanDerWaalsContact C-N 3.34Å; G137-D139 PolarHBondContact O-N 3.49Å; D139-A141 VanDerWaalsContact C-N 3.35Å; D139-A141 PolarHBondContact O-N 3.39Å; D139-K142 WeakPolarHBondContact O-CB 3.43Å; D139-K142 PolarHBondContact O-N 3.45Å; D139-M143 PolarHBondContact O-N 3.38Å
140I98.4Very high97.2Very high0 Ų033.2 Ų33.20%017%0.167CC..Hα-helixtrans-63.7-40.9175.3-62.3169.2000110.8Y46 F82 I84 V116 V136 G137 K142 M143 F144 V169 A173Y46-I140 HydrophobicContact CE1-CG1 4Å; Y46-I140 WeakPolarHBondContact OH-CA 3.34Å; Y46-I140 PolarHBondContact OH-N 2.79Å; F82-I140 HydrophobicContact CD2-CG2 4.27Å; F82-I140 HydrophobicContact CE2-CG2 4.5Å; I84-I140 HydrophobicContact CD1-CD1 3.8Å; I84-I140 HydrophobicContact CG1-CD1 4.45Å; V116-I140 HydrophobicContact CG1-CD1 3.95Å; V116-I140 HydrophobicContact CG1-CG1 4.2Å; V116-I140 HydrophobicContact CG2-CD1 4.43Å; V136-I140 HydrophobicContact CG1-CD1 4.14Å; V136-I140 WeakPolarHBondContact O-CG1 3.49Å; V136-I140 PolarHBondContact O-N 3.04Å; G137-I140 PolarHBondContact O-N 3.1Å; I140-K142 VanDerWaalsContact C-N 3.34Å; I140-K142 PolarHBondContact O-N 3.32Å; I140-M143 WeakPolarHBondContact O-CB 3.07Å; I140-M143 PolarHBondContact O-N 3.14Å; I140-M143 VanDerWaalsContact O-N 3.16Å; I140-F144 HydrophobicContact CG2-CD2 3.89Å; I140-F144 HydrophobicContact CG2-CE2 3.37Å; I140-F144 HydrophobicContact CG2-CZ 4.14Å; I140-F144 WeakPolarHBondContact O-CD2 3.2Å; I140-F144 PolarHBondContact O-N 2.99Å; I140-V169 HydrophobicContact CD1-CG1 3.46Å; I140-V169 VanDerWaalsContact CD1-CG1 3.46Å; I140-A173 HydrophobicContact CB-CB 3.87Å; I140-A173 HydrophobicContact CG2-CB 3.71Å
141A98.4Very high97Very high2 Ų235 Ų352%0.01717%0.174CC..Hα-helixtrans-58.7-45.2174.500000111.6G137 V138 D139 M143 F144 D145 V177G137-A141 PolarHBondContact O-N 3.34Å; V138-A141 PolarHBondContact O-N 2.96Å; D139-A141 VanDerWaalsContact C-N 3.35Å; D139-A141 PolarHBondContact O-N 3.39Å; A141-M143 VanDerWaalsContact C-N 3.29Å; A141-M143 PolarHBondContact O-N 2.94Å; A141-F144 PolarHBondContact O-N 3.44Å; A141-F144 VanDerWaalsContact O-N 3.12Å; A141-D145 PolarHBondContact O-N 3.48Å; A141-V177 HydrophobicContact CB-CB 4.17Å
142K97.6Very high96.9Very high102 Ų10237.4 Ų37.444%0.44318%0.18SC..Hα-helixtrans-61.2-36.2174.7-71172.2-177.9176.10112.5V138 D139 I140 W146V138-K142 WeakPolarHBondContact O-CG 3.11Å; V138-K142 PolarHBondContact O-N 2.91Å; D139-K142 WeakPolarHBondContact O-CB 3.43Å; D139-K142 PolarHBondContact O-N 3.45Å; I140-K142 VanDerWaalsContact C-N 3.34Å; I140-K142 PolarHBondContact O-N 3.32Å; K142-W146 WeakPolarHBondContact O-CB 3.44Å; K142-W146 PolarHBondContact O-N 3.39Å
143M97.4Very high96.9Very high1 Ų135.2 Ų35.21%0.00517%0.169CC..Hα-helixtrans-61.8-44.9172.7175.164.380.200111.3Y46 L61 T63 F82 D139 I140 A141 W146 L147Y46-M143 HydrophobicContact CD1-CE 4.14Å; Y46-M143 HydrophobicContact CD1-CG 4.34Å; Y46-M143 HydrophobicContact CD2-CE 3.26Å; Y46-M143 HydrophobicContact CE1-CB 4.22Å; Y46-M143 HydrophobicContact CE1-CE 4.4Å; Y46-M143 HydrophobicContact CE1-CG 4.18Å; Y46-M143 HydrophobicContact CE2-CE 3.61Å; Y46-M143 HydrophobicContact CG-CE 3.56Å; L61-M143 HydrophobicContact CB-CE 3.96Å; L61-M143 HydrophobicContact CB-SD 4.41Å; T63-M143 HydrophobicContact CG2-CB 4.07Å; T63-M143 HydrophobicContact CG2-CE 3.78Å; T63-M143 HydrophobicContact CG2-SD 3.76Å; F82-M143 HydrophobicContact CE2-CG 4.33Å; F82-M143 HydrophobicContact CZ-CG 4.33Å; D139-M143 PolarHBondContact O-N 3.38Å; I140-M143 WeakPolarHBondContact O-CB 3.07Å; I140-M143 PolarHBondContact O-N 3.14Å; I140-M143 VanDerWaalsContact O-N 3.16Å; A141-M143 VanDerWaalsContact C-N 3.29Å; A141-M143 PolarHBondContact O-N 2.94Å; M143-W146 PolarHBondContact O-N 3.34Å; M143-W146 HydrophobicContact SD-CE3 3.56Å; M143-W146 VanDerWaalsContact SD-CE3 3.56Å; M143-W146 HydrophobicContact SD-CZ3 3.75Å; M143-L147 HydrophobicContact CG-CD1 4.11Å; M143-L147 VanDerWaalsContact O-CG 3.29Å; M143-L147 WeakPolarHBondContact O-CG 3.32Å; M143-L147 PolarHBondContact O-N 3.12Å; M143-L147 HydrophobicContact SD-CD1 4.24Å; M143-L147 HydrophobicContact SD-CG 4.25Å
144F98.3Very high96.8Very high0 Ų037.2 Ų37.20%018%0.182CC..Hα-helixtrans-67.7-43177.6-70.2-51.5000113.2F82 I140 A141 W146 L147 Q148 L153 L155 V158 L160 V177 L181F82-F144 HydrophobicContact CB-CZ 4.46Å; F82-F144 HydrophobicContact CD1-CE1 4.03Å; F82-F144 AromaticContact CD1-CZ 3.92Å; F82-F144 HydrophobicContact CD1-CZ 3.92Å; F82-F144 HydrophobicContact CD2-CE1 4.25Å; F82-F144 HydrophobicContact CD2-CE2 4.39Å; F82-F144 AromaticContact CD2-CZ 3.62Å; F82-F144 HydrophobicContact CD2-CZ 3.62Å; F82-F144 AromaticContact CE1-CE1 3.73Å; F82-F144 HydrophobicContact CE1-CE1 3.73Å; F82-F144 HydrophobicContact CE1-CZ 4.01Å; F82-F144 AromaticContact CE2-CE1 3.94Å; F82-F144 HydrophobicContact CE2-CE1 3.94Å; F82-F144 AromaticContact CE2-CZ 3.7Å; F82-F144 HydrophobicContact CE2-CZ 3.7Å; F82-F144 HydrophobicContact CG-CE1 4.31Å; F82-F144 AromaticContact CG-CZ 3.75Å; F82-F144 HydrophobicContact CG-CZ 3.75Å; F82-F144 AromaticContact CZ-CE1 3.68Å; F82-F144 HydrophobicContact CZ-CE1 3.68Å; F82-F144 AromaticContact CZ-CZ 3.92Å; F82-F144 HydrophobicContact CZ-CZ 3.92Å; I140-F144 HydrophobicContact CG2-CD2 3.89Å; I140-F144 HydrophobicContact CG2-CE2 3.37Å; I140-F144 HydrophobicContact CG2-CZ 4.14Å; I140-F144 WeakPolarHBondContact O-CD2 3.2Å; I140-F144 PolarHBondContact O-N 2.99Å; A141-F144 PolarHBondContact O-N 3.44Å; A141-F144 VanDerWaalsContact O-N 3.12Å; F144-W146 VanDerWaalsContact C-N 3.26Å; F144-W146 PolarHBondContact O-N 2.8Å; F144-L147 HydrophobicContact CD1-CD1 4.24Å; F144-L147 PolarHBondContact O-N 3.07Å; F144-L147 VanDerWaalsContact O-N 3.13Å; F144-Q148 WeakPolarHBondContact O-CG 3.43Å; F144-Q148 PolarHBondContact O-N 2.61Å; F144-L153 HydrophobicContact CD1-CD2 4.05Å; F144-L155 HydrophobicContact CB-CD2 4.17Å; F144-V158 HydrophobicContact CD1-CG1 4.41Å; F144-V158 HydrophobicContact CD1-CG2 4.37Å; F144-V158 HydrophobicContact CE1-CG1 3.73Å; F144-V158 HydrophobicContact CE1-CG2 4.24Å; F144-V158 HydrophobicContact CE2-CG1 4.25Å; F144-V158 HydrophobicContact CZ-CG1 3.65Å; F144-L160 HydrophobicContact CE2-CD1 4.34Å; F144-L160 HydrophobicContact CE2-CD2 3.58Å; F144-L160 HydrophobicContact CZ-CD2 3.46Å; F144-L160 VanDerWaalsContact CZ-CD2 3.46Å; F144-V177 HydrophobicContact CB-CG2 3.67Å; F144-L181 HydrophobicContact CD2-CD2 4.25Å
145D98.1Very high96.9Very high19 Ų1935 Ų3510%0.10217%0.171CC..Hα-helixtrans-54.2-46.3173.1-80.26.1000110.7A141 Q148 E149 V177 K178A141-D145 PolarHBondContact O-N 3.48Å; D145-Q148 WeakPolarHBondContact O-CB 3.47Å; D145-Q148 PolarHBondContact O-N 3.42Å; D145-E149 WeakPolarHBondContact O-CG 3.38Å; D145-E149 PolarHBondContact O-N 3.47Å; D145-V177 WeakPolarHBondContact OD1-CG2 3.27Å; D145-K178 WeakPolarHBondContact OD1-CB 3.43Å; D145-K178 PolarHBondContact OD1-N 3.15Å; D145-K178 VanDerWaalsContact OD2-CD 3.31Å; D145-K178 WeakPolarHBondContact OD2-CD 3.12Å; D145-K178 WeakPolarHBondContact OD2-CE 3.47Å; D145-K178 WeakPolarHBondContact OD2-CG 3.03Å; D145-K178 IonicContact OD2-NZ 3.61Å; D145-K178 PolarHBondContact OD2-NZ 3.45Å
146W97.3Very high96.9Very high21 Ų2140.5 Ų40.58%0.0819%0.192CC..Hα-helixtrans-63.8-43.1177174.369.4000112.5Q62 T63 G64 L69 K142 M143 F144 Q148 E149 E150Q62-W146 WeakPolarHBondContact O-CH2 3.17Å; T63-W146 HydrophobicContact CG2-CB 4.31Å; T63-W146 HydrophobicContact CG2-CD2 4.35Å; T63-W146 HydrophobicContact CG2-CE3 4.17Å; T63-W146 HydrophobicContact CG2-CG 4.41Å; G64-W146 VanDerWaalsContact N-NE1 3.17Å; L69-W146 HydrophobicContact CD1-CH2 3.74Å; L69-W146 HydrophobicContact CD1-CZ2 4.13Å; L69-W146 HydrophobicContact CD1-CZ3 4.3Å; L69-W146 HydrophobicContact CD2-CH2 3.76Å; L69-W146 HydrophobicContact CD2-CZ3 3.87Å; L69-W146 HydrophobicContact CG-CH2 3.72Å; L69-W146 HydrophobicContact CG-CZ2 4.46Å; L69-W146 HydrophobicContact CG-CZ3 4.32Å; K142-W146 WeakPolarHBondContact O-CB 3.44Å; K142-W146 PolarHBondContact O-N 3.39Å; M143-W146 PolarHBondContact O-N 3.34Å; M143-W146 HydrophobicContact SD-CE3 3.56Å; M143-W146 VanDerWaalsContact SD-CE3 3.56Å; M143-W146 HydrophobicContact SD-CZ3 3.75Å; F144-W146 VanDerWaalsContact C-N 3.26Å; F144-W146 PolarHBondContact O-N 2.8Å; W146-Q148 VanDerWaalsContact C-N 3.32Å; W146-Q148 PolarHBondContact O-N 3.01Å; W146-E149 PolarHBondContact O-N 2.86Å; W146-E150 HydrophobicContact CD2-CG 4.38Å; W146-E150 HydrophobicContact CG-CG 4.38Å; W146-E150 HydrophobicContact CZ2-CG 4.22Å; W146-E150 WeakPolarHBondContact O-CB 3.32Å; W146-E150 PolarHBondContact O-N 2.97Å
147L97.1Very high96.8Very high0 Ų043 Ų430%021%0.206CC..Hα-helixtrans-65-33.9176-70.7171.2000112.6L69 F74 M143 F144 H151 K152 L153L69-L147 HydrophobicContact CD1-CD2 4.29Å; L69-L147 HydrophobicContact CD2-CD2 3.6Å; F74-L147 HydrophobicContact CE1-CD2 4.15Å; F74-L147 HydrophobicContact CE2-CD1 4.47Å; F74-L147 HydrophobicContact CZ-CD1 4.2Å; F74-L147 HydrophobicContact CZ-CD2 4.17Å; M143-L147 HydrophobicContact CG-CD1 4.11Å; M143-L147 VanDerWaalsContact O-CG 3.29Å; M143-L147 WeakPolarHBondContact O-CG 3.32Å; M143-L147 PolarHBondContact O-N 3.12Å; M143-L147 HydrophobicContact SD-CD1 4.24Å; M143-L147 HydrophobicContact SD-CG 4.25Å; F144-L147 HydrophobicContact CD1-CD1 4.24Å; F144-L147 PolarHBondContact O-N 3.07Å; F144-L147 VanDerWaalsContact O-N 3.13Å; L147-H151 CarbonylContact O-C 3.52Å; L147-H151 WeakPolarHBondContact O-CA 3.37Å; L147-H151 PolarHBondContact O-N 3Å; L147-K152 PolarHBondContact O-N 2.7Å; L147-L153 HydrophobicContact CB-CB 4.11Å; L147-L153 HydrophobicContact CB-CD2 3.78Å; L147-L153 HydrophobicContact CD1-CD2 3.99Å; L147-L153 PolarHBondContact O-N 3.14Å
148Q96.6Very high96.8Very high48 Ų4843.1 Ų43.122%0.22421%0.206CC..Hα-helixtrans-64.9-46.2171.7-74.5172.3-99.500111F144 D145 W146 K152 L153 L155 K178F144-Q148 WeakPolarHBondContact O-CG 3.43Å; F144-Q148 PolarHBondContact O-N 2.61Å; D145-Q148 WeakPolarHBondContact O-CB 3.47Å; D145-Q148 PolarHBondContact O-N 3.42Å; W146-Q148 VanDerWaalsContact C-N 3.32Å; W146-Q148 PolarHBondContact O-N 3.01Å; Q148-K152 VanDerWaalsContact O-CA 3.24Å; Q148-K152 WeakPolarHBondContact O-CA 3.43Å; Q148-K152 PolarHBondContact O-N 3.17Å; Q148-K152 VanDerWaalsContact O-N 3.13Å; Q148-L153 WeakPolarHBondContact CG-O 3.41Å; Q148-L155 HydrophobicContact CG-CD2 3.88Å; Q148-L155 HydrophobicContact CG-CG 4.09Å; Q148-K178 PolarHBondContact NE2-O 3.22Å; Q148-K178 VanDerWaalsContact NE2-O 3.08Å
149E95.1Very high96.9Very high111 Ų11142.4 Ų42.452%0.51920%0.201SC..Hα-helixtrans-65.7-50.9-178.4-73.2173.4-17100111.4D145 W146 K152 K178D145-E149 WeakPolarHBondContact O-CG 3.38Å; D145-E149 PolarHBondContact O-N 3.47Å; W146-E149 PolarHBondContact O-N 2.86Å; E149-K152 PolarHBondContact O-NZ 2.71Å; E149-K178 IonicContact OE1-NZ 2.79Å
150E93.3Very high96.9Very high82 Ų8241.1 Ų41.138%0.38319%0.194SC..Hα-helixtrans-78.5-42.4-174.3-71.6-58.8144.300114.3L69 W146L69-E150 HydrophobicContact CD1-CB 4.41Å; W146-E150 HydrophobicContact CD2-CG 4.38Å; W146-E150 HydrophobicContact CG-CG 4.38Å; W146-E150 HydrophobicContact CZ2-CG 4.22Å; W146-E150 WeakPolarHBondContact O-CB 3.32Å; W146-E150 PolarHBondContact O-N 2.97Å
151H90Very high96.9Very high48 Ų4841.1 Ų41.122%0.22219%0.194CC..Hα-helixtrans-123.37.9-168.7-106.5-101.3000114.1L69 S76 L147 L153L69-H151 HydrophobicContact CD1-CB 4.41Å; L69-H151 WeakPolarHBondContact CD1-CD2 3.47Å; S76-H151 WeakPolarHBondContact CB-O 3.14Å; S76-H151 PolarHBondContact OG-O 3.18Å; L147-H151 CarbonylContact O-C 3.52Å; L147-H151 WeakPolarHBondContact O-CA 3.37Å; L147-H151 PolarHBondContact O-N 3Å; H151-L153 PolarHBondContact O-N 3.26Å
152K93.8Very high97Very high157 Ų15741 Ų4168%0.68319%0.194SC*.  trans54.336.3178.3-51.7-55.3177.1-148.10112.4L147 Q148 E149 P154L147-K152 PolarHBondContact O-N 2.7Å; Q148-K152 VanDerWaalsContact O-CA 3.24Å; Q148-K152 WeakPolarHBondContact O-CA 3.43Å; Q148-K152 PolarHBondContact O-N 3.17Å; Q148-K152 VanDerWaalsContact O-N 3.13Å; E149-K152 PolarHBondContact O-NZ 2.71Å; K152-P154 WeakPolarHBondContact O-CD 3.26Å
153L96.8Very high97Very high4 Ų436.6 Ų36.62%0.02117%0.174CC..  trans-56.6117.9176.1177.267000109.9F74 F144 L147 Q148 H151 L155 V158F74-L153 HydrophobicContact CE1-CD1 4.49Å; F74-L153 HydrophobicContact CZ-CD1 4.14Å; F74-L153 HydrophobicContact CZ-CD2 4.4Å; F144-L153 HydrophobicContact CD1-CD2 4.05Å; L147-L153 HydrophobicContact CB-CB 4.11Å; L147-L153 HydrophobicContact CB-CD2 3.78Å; L147-L153 HydrophobicContact CD1-CD2 3.99Å; L147-L153 PolarHBondContact O-N 3.14Å; Q148-L153 WeakPolarHBondContact CG-O 3.41Å; H151-L153 PolarHBondContact O-N 3.26Å; L153-L155 PolarHBondContact O-N 3.45Å; L153-V158 HydrophobicContact CD1-CG2 4.44Å; L153-V158 HydrophobicContact CD2-CG2 3.85Å; L153-V158 HydrophobicContact CG-CG2 4.2Å
154P97.6Very high97Very high46 Ų4637 Ų3730%0.29918%0.177SC..  trans-74.9120.7171.729.2-32.4000109.9S76 K152 E156 N157S76-P154 WeakPolarHBondContact O-CD 3.24Å; K152-P154 WeakPolarHBondContact O-CD 3.26Å; P154-E156 HydrophobicContact CB-CG 4.01Å; P154-E156 PolarHBondContact O-N 3.43Å; P154-N157 HydrophobicContact CG-CB 4.14Å; P154-N157 WeakPolarHBondContact CG-ND2 3.45Å; P154-N157 WeakPolarHBondContact O-CB 3.42Å; P154-N157 PolarHBondContact O-N 2.87Å
155L98.3Very high97Very high13 Ų1337 Ų377%0.06818%0.177CC..G310 helixtrans-63.4-25-177.5-67.1-174.7000113.6F144 Q148 L153 N157 V158 V177 T180 L181 G182F144-L155 HydrophobicContact CB-CD2 4.17Å; Q148-L155 HydrophobicContact CG-CD2 3.88Å; Q148-L155 HydrophobicContact CG-CG 4.09Å; L153-L155 PolarHBondContact O-N 3.45Å; L155-N157 PolarHBondContact O-N 3.44Å; L155-V158 HydrophobicContact CD2-CG2 4.24Å; L155-V158 WeakPolarHBondContact O-CB 3.5Å; L155-V158 PolarHBondContact O-N 3.36Å; L155-V177 HydrophobicContact CD1-CG1 4.27Å; L155-V177 HydrophobicContact CD1-CG2 3.89Å; L155-V177 HydrophobicContact CD2-CG2 4.29Å; L155-T180 WeakPolarHBondContact CB-O 3.5Å; L155-L181 HydrophobicContact CB-CD2 4.48Å; L155-L181 HydrophobicContact CD1-CD2 4.48Å; L155-L181 HydrophobicContact CD2-CD2 4Å; L155-G182 PolarHBondContact O-N 2.9Å
156E97.6Very high97Very high142 Ų14236.1 Ų36.166%0.66417%0.172SC*.G310 helixtrans-59.9-22.5172.657.7177.5-15200113.4P154P154-E156 HydrophobicContact CB-CG 4.01Å; P154-E156 PolarHBondContact O-N 3.43Å
157N97.3Very high97Very high52 Ų5235.1 Ų35.128%0.27817%0.169SC..G310 helixtrans-89.90.1175.5-74-11.9000113.3K79 T80 P154 L155K79-N157 WeakPolarHBondContact CA-O 3.47Å; T80-N157 PolarHBondContact N-O 2.84Å; P154-N157 HydrophobicContact CG-CB 4.14Å; P154-N157 WeakPolarHBondContact CG-ND2 3.45Å; P154-N157 WeakPolarHBondContact O-CB 3.42Å; P154-N157 PolarHBondContact O-N 2.87Å; L155-N157 PolarHBondContact O-N 3.44Å
158V98.7Very high97.1Very high2 Ų235.1 Ų35.11%0.01217%0.169CC..EExtended strand (participates in β ladder)trans-89.8131.8179.7179.50000110.6T80 F144 L153 L155 L160 L181 G182 R183T80-V158 WeakPolarHBondContact O-CA 3.5Å; F144-V158 HydrophobicContact CD1-CG1 4.41Å; F144-V158 HydrophobicContact CD1-CG2 4.37Å; F144-V158 HydrophobicContact CE1-CG1 3.73Å; F144-V158 HydrophobicContact CE1-CG2 4.24Å; F144-V158 HydrophobicContact CE2-CG1 4.25Å; F144-V158 HydrophobicContact CZ-CG1 3.65Å; L153-V158 HydrophobicContact CD1-CG2 4.44Å; L153-V158 HydrophobicContact CD2-CG2 3.85Å; L153-V158 HydrophobicContact CG-CG2 4.2Å; L155-V158 HydrophobicContact CD2-CG2 4.24Å; L155-V158 WeakPolarHBondContact O-CB 3.5Å; L155-V158 PolarHBondContact O-N 3.36Å; V158-L160 HydrophobicContact CG1-CD2 3.85Å; V158-L181 HydrophobicContact CB-CD2 4.19Å; V158-L181 HydrophobicContact CG1-CD2 3.98Å; V158-G182 PolarHBondContact O-N 2.95Å; V158-R183 PolarHBondContact O-N 2.75Å
159H98.8Very high97.2Very high13 Ų1332.8 Ų32.86%0.0616%0.158CC..EExtended strand (participates in β ladder)trans-126.6114.9172.8-175.8-175.7000110.2T80 I81 F82 R183 T185 Y315T80-H159 PolarHBondContact O-N 2.86Å; I81-H159 CarbonylContact C-O 3.54Å; I81-H159 VanDerWaalsContact CA-O 3.28Å; I81-H159 WeakPolarHBondContact CA-O 3.48Å; I81-H159 HydrophobicContact CG1-CB 4.31Å; F82-H159 PolarHBondContact N-O 3.33Å; H159-R183 CarbonylContact C-O 3.59Å; H159-R183 VanDerWaalsContact CA-O 3.3Å; H159-R183 WeakPolarHBondContact CA-O 3.33Å; H159-R183 HydrophobicContact CB-CB 4.43Å; H159-R183 PolarHBondContact CD2-O 3.2Å; H159-T185 PolarHBondContact NE2-OG1 2.94Å; H159-Y315 AromaticContact ND1-CE2 3.88Å
160L98.9Very high97.4Very high0 Ų027.5 Ų27.50%013%0.133CC..EExtended strand (participates in β ladder)trans-91.6132.8170.4-47.2-172.4000110.4F82 I84 F144 V158 A170 A173 L181 R183 I184 T185F82-L160 HydrophobicContact CB-CD2 3.65Å; F82-L160 HydrophobicContact CG-CD2 4.24Å; F82-L160 CarbonylContact O-C 3.53Å; F82-L160 WeakPolarHBondContact O-CA 3.29Å; I84-L160 HydrophobicContact CD1-CB 4.48Å; F144-L160 HydrophobicContact CE2-CD1 4.34Å; F144-L160 HydrophobicContact CE2-CD2 3.58Å; F144-L160 HydrophobicContact CZ-CD2 3.46Å; F144-L160 VanDerWaalsContact CZ-CD2 3.46Å; V158-L160 HydrophobicContact CG1-CD2 3.85Å; L160-A170 HydrophobicContact CB-CB 3.92Å; L160-A170 HydrophobicContact CD1-CB 3.95Å; L160-A173 HydrophobicContact CD1-CB 3.92Å; L160-L181 HydrophobicContact CD1-CD1 3.5Å; L160-L181 VanDerWaalsContact CD1-CD1 3.5Å; L160-L181 HydrophobicContact CG-CD1 3.95Å; L160-R183 PolarHBondContact N-O 3.45Å; L160-I184 HydrophobicContact CB-CG1 4.13Å; L160-I184 HydrophobicContact CD1-CG1 4.27Å; L160-I184 HydrophobicContact CG-CG1 4.29Å; L160-I184 CarbonylContact O-C 3.45Å; L160-I184 WeakPolarHBondContact O-CA 3.29Å; L160-T185 PolarHBondContact O-N 3.22Å
161I98.9Very high97.7Very high1 Ų123.6 Ų23.61%0.00512%0.115CC..EExtended strand (participates in β ladder)trans-118.7104173.9-57.1168.8000107.1I81 F82 I83 I84 L100 V104 L187 F275I81-I161 HydrophobicContact CG2-CD1 3.67Å; I81-I161 HydrophobicContact CG2-CG1 4.27Å; F82-I161 PolarHBondContact O-N 3.2Å; I83-I161 WeakPolarHBondContact CA-O 3.47Å; I83-I161 HydrophobicContact CG1-CB 4.47Å; I83-I161 HydrophobicContact CG1-CD1 4.42Å; I84-I161 PolarHBondContact N-O 3.06Å; L100-I161 HydrophobicContact CD2-CG2 4.13Å; V104-I161 HydrophobicContact CG2-CD1 4.16Å; I161-L187 HydrophobicContact CG2-CD1 3.53Å; I161-L187 HydrophobicContact CG2-CG 4.12Å; I161-F275 HydrophobicContact CD1-CE1 3.69Å; I161-F275 HydrophobicContact CD1-CZ 3.85Å; I161-F275 HydrophobicContact CG1-CE1 4.47Å; I161-F275 HydrophobicContact CG1-CZ 4.27Å
162G98.8Very high98.1Very high0 Ų021.9 Ų21.90%011%0.107CC..EExtended strand (participates in β ladder)trans-108.5131.7-177.500000111.9I84 G166 T185 L187I84-G162 WeakPolarHBondContact O-CA 3.45Å; G162-G166 WeakPolarHBondContact CA-O 3.38Å; G162-T185 PolarHBondContact N-O 2.9Å; G162-L187 PolarHBondContact O-N 2.89Å
163Y98.3Very high98.3Very high8 Ų814.4 Ų14.43%0.0317%0.074CC..EExtended strand (participates in β ladder)trans-107.2134.1175.1169-113.2000111.4I84 G86 W96 L165 G166 L187 H268 E269 V272I84-Y163 PolarHBondContact O-N 2.87Å; G86-Y163 VanDerWaalsContact CA-O 3.3Å; G86-Y163 WeakPolarHBondContact CA-O 3.34Å; G86-Y163 PolarHBondContact N-O 3.21Å; W96-Y163 AromaticContact CE2-CD1 3.83Å; W96-Y163 AromaticContact CE2-CE1 3.84Å; W96-Y163 AromaticContact CH2-CD1 3.77Å; W96-Y163 HydrophobicContact CH2-CD1 3.77Å; W96-Y163 HydrophobicContact CH2-CG 4.16Å; W96-Y163 AromaticContact CZ2-CD1 3.27Å; W96-Y163 HydrophobicContact CZ2-CD1 3.27Å; W96-Y163 AromaticContact CZ2-CE1 3.68Å; W96-Y163 HydrophobicContact CZ2-CE1 3.68Å; W96-Y163 HydrophobicContact CZ2-CG 4.05Å; W96-Y163 AromaticContact NE1-CE1 3.78Å; Y163-L165 PolarHBondContact O-N 3.1Å; Y163-G166 WeakPolarHBondContact O-CA 3.46Å; Y163-G166 PolarHBondContact O-N 2.91Å; Y163-L187 WeakPolarHBondContact CA-O 3.37Å; Y163-L187 HydrophobicContact CD2-CB 4.2Å; Y163-L187 WeakPolarHBondContact CD2-O 3.49Å; Y163-H268 AromaticContact CE2-CD2 3.86Å; Y163-H268 AromaticContact CZ-CD2 3.52Å; Y163-H268 AromaticContact CZ-NE2 3.97Å; Y163-H268 PolarHBondContact OH-CD2 3.44Å; Y163-E269 VanDerWaalsContact OH-CG 3.28Å; Y163-E269 WeakPolarHBondContact OH-CG 3.26Å; Y163-V272 HydrophobicContact CD2-CG2 3.56Å; Y163-V272 HydrophobicContact CE2-CG2 3.89Å; Y163-V272 HydrophobicContact CG-CG2 4.04Å
164S96.8Very high98.4Very high10 Ų1014.5 Ų14.57%0.078%0.077CC..THydrogen-bonded Turntrans55.3-123.8177-169.60000111.6G166 A167 L187 D188 A190 H268S164-G166 PolarHBondContact O-N 3.42Å; S164-A167 WeakPolarHBondContact O-CB 3.29Å; S164-A167 PolarHBondContact O-N 3.29Å; S164-A167 VanDerWaalsContact O-N 3.09Å; S164-L187 PolarHBondContact N-O 3.33Å; S164-D188 WeakPolarHBondContact CA-O 3.41Å; S164-A190 PolarHBondContact O-N 2.96Å; S164-H268 WeakPolarHBondContact CB-NE2 3.45Å; S164-H268 PolarHBondContact OG-NE2 3.16Å
165L98.1Very high98.5Very high0 Ų015.2 Ų15.20%08%0.08CC..Hα-helixtrans-55-32.1171.6-68.9-170.8000113.3W87 W118 Y126 A129 V130 T133 Y163 A167 H168 V169 A190 F194W87-L165 HydrophobicContact CB-CD1 3.69Å; W87-L165 HydrophobicContact CB-CG 4.1Å; W87-L165 HydrophobicContact CG-CD1 4.42Å; W118-L165 HydrophobicContact CH2-CB 3.95Å; W118-L165 HydrophobicContact CH2-CD1 3.93Å; W118-L165 HydrophobicContact CZ2-CB 4.02Å; Y126-L165 HydrophobicContact CE2-CD2 4.24Å; Y126-L165 HydrophobicContact CE2-CG 4.5Å; A129-L165 HydrophobicContact CB-CD1 3.84Å; V130-L165 HydrophobicContact CG2-CD1 4.49Å; V130-L165 HydrophobicContact CG2-CD2 3.84Å; T133-L165 HydrophobicContact CG2-CB 4.04Å; T133-L165 HydrophobicContact CG2-CD1 4.34Å; T133-L165 HydrophobicContact CG2-CD2 4.28Å; T133-L165 HydrophobicContact CG2-CG 4.47Å; Y163-L165 PolarHBondContact O-N 3.1Å; L165-A167 PolarHBondContact O-N 3.15Å; L165-H168 PolarHBondContact O-N 3.38Å; L165-H168 VanDerWaalsContact O-N 3.08Å; L165-V169 PolarHBondContact O-N 3.15Å; L165-V169 VanDerWaalsContact O-N 3.09Å; L165-A190 HydrophobicContact CD2-CB 3.75Å; L165-A190 HydrophobicContact CG-CB 4.48Å; L165-F194 HydrophobicContact CD2-CD2 4.49Å; L165-F194 HydrophobicContact CD2-CE2 3.58Å; L165-F194 HydrophobicContact CD2-CZ 4.34Å
166G98.6Very high98.5Very high0 Ų020.3 Ų20.30%010%0.099CC..Hα-helixtrans-62.4-23.2177.900000113.7H85 G162 Y163 S164 A170H85-G166 VanDerWaalsContact O-CA 3.25Å; H85-G166 WeakPolarHBondContact O-CA 3.5Å; H85-G166 PolarHBondContact O-N 2.93Å; G162-G166 WeakPolarHBondContact CA-O 3.38Å; Y163-G166 WeakPolarHBondContact O-CA 3.46Å; Y163-G166 PolarHBondContact O-N 2.91Å; S164-G166 PolarHBondContact O-N 3.42Å; G166-A170 WeakPolarHBondContact O-CB 3.33Å; G166-A170 PolarHBondContact O-N 3.45Å
167A98.8Very high98.5Very high0 Ų014 Ų140%07%0.071CC..Hα-helixtrans-68.5-40.317300000112S164 L165 A170 G171 P189 L203S164-A167 WeakPolarHBondContact O-CB 3.29Å; S164-A167 PolarHBondContact O-N 3.29Å; S164-A167 VanDerWaalsContact O-N 3.09Å; L165-A167 PolarHBondContact O-N 3.15Å; A167-A170 WeakPolarHBondContact O-CB 3.39Å; A167-A170 PolarHBondContact O-N 3.47Å; A167-G171 PolarHBondContact O-N 2.63Å; A167-P189 HydrophobicContact CB-CB 3.64Å; A167-P189 HydrophobicContact CB-CG 3.62Å; A167-L203 HydrophobicContact CB-CD2 4.25Å
168H98.8Very high98.5Very high0 Ų017.9 Ų17.90%09%0.085CC..Hα-helixtrans-71.1-38.4175.1-58.3-75.3000111.3L165 A170 G171 F172 A190 F194 R202 L203L165-H168 PolarHBondContact O-N 3.38Å; L165-H168 VanDerWaalsContact O-N 3.08Å; H168-A170 VanDerWaalsContact C-N 3.28Å; H168-A170 PolarHBondContact O-N 3.43Å; H168-G171 WeakPolarHBondContact O-CA 3.47Å; H168-G171 PolarHBondContact O-N 2.87Å; H168-G171 VanDerWaalsContact O-N 3.1Å; H168-F172 HydrophobicContact CB-CE2 4.31Å; H168-F172 WeakPolarHBondContact O-CD2 3.49Å; H168-F172 PolarHBondContact O-N 2.03Å; H168-A190 PolarHBondContact NE2-N 3.48Å; H168-A190 PolarHBondContact NE2-O 3.44Å; H168-F194 HydrophobicContact CB-CD1 4.36Å; H168-F194 HydrophobicContact CB-CE1 3.76Å; H168-F194 HydrophobicContact CB-CE2 4.44Å; H168-F194 HydrophobicContact CB-CZ 3.8Å; H168-F194 AromaticContact CD2-CD2 3.64Å; H168-F194 AromaticContact CD2-CE2 3.65Å; H168-F194 AromaticContact CD2-CG 3.9Å; H168-F194 AromaticContact CD2-CZ 3.9Å; H168-F194 AromaticContact CE1-CD1 3.83Å; H168-F194 AromaticContact CE1-CG 3.55Å; H168-F194 AromaticContact CG-CD1 3.75Å; H168-F194 AromaticContact CG-CE1 3.61Å; H168-F194 AromaticContact CG-CE2 3.96Å; H168-F194 AromaticContact CG-CG 3.95Å; H168-F194 AromaticContact CG-CZ 3.72Å; H168-F194 AromaticContact ND1-CD1 3.51Å; H168-F194 AromaticContact ND1-CE1 3.82Å; H168-F194 AromaticContact ND1-CG 3.72Å; H168-F194 AromaticContact NE2-CD2 3.67Å; H168-F194 AromaticContact NE2-CG 3.7Å; H168-R202 WeakPolarHBondContact ND1-CB 3.42Å; H168-L203 PolarHBondContact ND1-N 3.45Å
169V98.9Very high98.5Very high0 Ų020 Ų200%011%0.107CC..Hα-helixtrans-54.9-44.8169.9172.50000111.1I84 W118 T133 V136 G137 I140 L165 G171 F172 A173I84-V169 HydrophobicContact CD1-CG1 4.34Å; I84-V169 HydrophobicContact CG2-CB 4.07Å; I84-V169 HydrophobicContact CG2-CG1 3.8Å; W118-V169 HydrophobicContact CZ2-CG2 4.4Å; T133-V169 HydrophobicContact CG2-CG2 3.87Å; V136-V169 HydrophobicContact CB-CG1 4.04Å; V136-V169 HydrophobicContact CB-CG2 4.29Å; V136-V169 HydrophobicContact CG1-CG1 3.51Å; V136-V169 HydrophobicContact CG1-CG2 4.31Å; G137-V169 WeakPolarHBondContact CA-O 3.34Å; I140-V169 HydrophobicContact CD1-CG1 3.46Å; I140-V169 VanDerWaalsContact CD1-CG1 3.46Å; L165-V169 PolarHBondContact O-N 3.15Å; L165-V169 VanDerWaalsContact O-N 3.09Å; V169-G171 VanDerWaalsContact C-N 3.34Å; V169-F172 PolarHBondContact O-N 3.28Å; V169-A173 WeakPolarHBondContact O-CB 3.31Å; V169-A173 PolarHBondContact O-N 3.26Å
170A98.9Very high98.4Very high0 Ų022.9 Ų22.90%013%0.126CC..Hα-helixtrans-62-41.5175.500000112.2I84 L160 G166 A167 H168 A173 G174 I184I84-A170 HydrophobicContact CD1-CB 3.95Å; L160-A170 HydrophobicContact CB-CB 3.92Å; L160-A170 HydrophobicContact CD1-CB 3.95Å; G166-A170 WeakPolarHBondContact O-CB 3.33Å; G166-A170 PolarHBondContact O-N 3.45Å; A167-A170 WeakPolarHBondContact O-CB 3.39Å; A167-A170 PolarHBondContact O-N 3.47Å; H168-A170 VanDerWaalsContact C-N 3.28Å; H168-A170 PolarHBondContact O-N 3.43Å; A170-A173 WeakPolarHBondContact O-CB 3.48Å; A170-A173 PolarHBondContact O-N 3.07Å; A170-G174 PolarHBondContact O-N 2.96Å; A170-I184 HydrophobicContact CB-CG2 3.8Å; A170-I184 WeakPolarHBondContact O-CD1 3.38Å
171G98.8Very high98.4Very high0 Ų022.9 Ų22.90%013%0.126CC..Hα-helixtrans-59.6-51.417500000112.3A167 H168 V169 A173 G174 T175 D207A167-G171 PolarHBondContact O-N 2.63Å; H168-G171 WeakPolarHBondContact O-CA 3.47Å; H168-G171 PolarHBondContact O-N 2.87Å; H168-G171 VanDerWaalsContact O-N 3.1Å; V169-G171 VanDerWaalsContact C-N 3.34Å; G171-A173 VanDerWaalsContact C-N 3.31Å; G171-A173 PolarHBondContact O-N 2.98Å; G171-G174 CarbonylContact O-C 3.57Å; G171-G174 WeakPolarHBondContact O-CA 3.37Å; G171-G174 PolarHBondContact O-N 2.8Å; G171-T175 PolarHBondContact O-N 3.15Å; G171-T175 PolarHBondContact O-OG1 2.93Å; G171-D207 WeakPolarHBondContact CA-OD2 3.35Å
172F98.8Very high98.4Very high11 Ų1123.4 Ų23.45%0.04813%0.132CC..Hα-helixtrans-57.2-42.6174.3-68.8-55.3000112.3T133 L134 H168 V169 G174 T175 Y176 F194 Q200 K201T133-F172 WeakPolarHBondContact OG1-CE2 3.27Å; L134-F172 HydrophobicContact CB-CD2 4.38Å; L134-F172 HydrophobicContact CB-CE1 4.48Å; L134-F172 HydrophobicContact CB-CE2 4.28Å; L134-F172 HydrophobicContact CB-CZ 4.32Å; L134-F172 HydrophobicContact CD1-CB 4.47Å; L134-F172 HydrophobicContact CD1-CD1 3.57Å; L134-F172 HydrophobicContact CD1-CE1 3.84Å; L134-F172 HydrophobicContact CD1-CG 4.01Å; L134-F172 HydrophobicContact CD1-CZ 4.5Å; H168-F172 HydrophobicContact CB-CE2 4.31Å; H168-F172 WeakPolarHBondContact O-CD2 3.49Å; H168-F172 PolarHBondContact O-N 2.03Å; V169-F172 PolarHBondContact O-N 3.28Å; F172-G174 VanDerWaalsContact C-N 3.28Å; F172-G174 PolarHBondContact O-N 3.33Å; F172-T175 PolarHBondContact O-N 3.19Å; F172-Y176 HydrophobicContact CD1-CE2 4.36Å; F172-Y176 VanDerWaalsContact O-CD2 3.26Å; F172-Y176 WeakPolarHBondContact O-CD2 3.48Å; F172-Y176 PolarHBondContact O-N 2.65Å; F172-F194 HydrophobicContact CE2-CE1 4.44Å; F172-Q200 WeakPolarHBondContact CE1-O 3.33Å; F172-K201 VanDerWaalsContact CZ-C 3.49Å; F172-K201 WeakPolarHBondContact CZ-O 3.25Å
173A98.8Very high98.4Very high0 Ų024.9 Ų24.90%014%0.137CC..Hα-helixtrans-58.9-40.7174.900000112.3G137 I140 L160 V169 A170 G171 V177G137-A173 VanDerWaalsContact O-CA 3.29Å; G137-A173 WeakPolarHBondContact O-CA 3.24Å; G137-A173 WeakPolarHBondContact O-CB 3.49Å; I140-A173 HydrophobicContact CB-CB 3.87Å; I140-A173 HydrophobicContact CG2-CB 3.71Å; L160-A173 HydrophobicContact CD1-CB 3.92Å; V169-A173 WeakPolarHBondContact O-CB 3.31Å; V169-A173 PolarHBondContact O-N 3.26Å; A170-A173 WeakPolarHBondContact O-CB 3.48Å; A170-A173 PolarHBondContact O-N 3.07Å; G171-A173 VanDerWaalsContact C-N 3.31Å; G171-A173 PolarHBondContact O-N 2.98Å; A173-V177 WeakPolarHBondContact O-CB 2.93Å; A173-V177 PolarHBondContact O-N 2.85Å
174G98.6Very high98.4Very high7 Ų724.5 Ų24.57%0.07214%0.136CC..Hα-helixtrans-65.7-38.2174.500000114.2A170 G171 F172 D207A170-G174 PolarHBondContact O-N 2.96Å; G171-G174 CarbonylContact O-C 3.57Å; G171-G174 WeakPolarHBondContact O-CA 3.37Å; G171-G174 PolarHBondContact O-N 2.8Å; F172-G174 VanDerWaalsContact C-N 3.28Å; F172-G174 PolarHBondContact O-N 3.33Å; G174-D207 CarbonylContact C-O 3.59Å; G174-D207 WeakPolarHBondContact CA-O 3.25Å
175T98.3Very high98.5Very high60 Ų6024 Ų2437%0.36813%0.132SC..Hα-helixtrans-68.3-37178.4-58.60000113.1G171 F172 D207G171-T175 PolarHBondContact O-N 3.15Å; G171-T175 PolarHBondContact O-OG1 2.93Å; F172-T175 PolarHBondContact O-N 3.19Å; T175-D207 PolarHBondContact OG1-OD1 3.22Å
176Y98.4Very high98.5Very high120 Ų12024 Ų2447%0.47113%0.132SC..Hα-helixtrans-98.8-9.1-171.7-74.4-82.2000114.8L134 V138 F172L134-Y176 HydrophobicContact CD1-CD2 4.32Å; L134-Y176 HydrophobicContact CD1-CE2 3.45Å; L134-Y176 VanDerWaalsContact CD1-CE2 3.45Å; V138-Y176 HydrophobicContact CG2-CD1 4.21Å; V138-Y176 HydrophobicContact CG2-CD2 3.75Å; V138-Y176 HydrophobicContact CG2-CE1 4.45Å; V138-Y176 HydrophobicContact CG2-CE2 4.05Å; V138-Y176 HydrophobicContact CG2-CG 3.85Å; F172-Y176 HydrophobicContact CD1-CE2 4.36Å; F172-Y176 VanDerWaalsContact O-CD2 3.26Å; F172-Y176 WeakPolarHBondContact O-CD2 3.48Å; F172-Y176 PolarHBondContact O-N 2.65Å
177V98.4Very high98.5Very high11 Ų1124 Ų247%0.06713%0.132CC..SBendtrans-73.9146.9177.570.10000111.6A141 F144 D145 L155 A173 G179 L181A141-V177 HydrophobicContact CB-CB 4.17Å; F144-V177 HydrophobicContact CB-CG2 3.67Å; D145-V177 WeakPolarHBondContact OD1-CG2 3.27Å; L155-V177 HydrophobicContact CD1-CG1 4.27Å; L155-V177 HydrophobicContact CD1-CG2 3.89Å; L155-V177 HydrophobicContact CD2-CG2 4.29Å; A173-V177 WeakPolarHBondContact O-CB 2.93Å; A173-V177 PolarHBondContact O-N 2.85Å; V177-G179 VanDerWaalsContact C-N 3.34Å; V177-G179 PolarHBondContact O-N 2.85Å; V177-L181 HydrophobicContact CG1-CD2 3.99Å; V177-L181 HydrophobicContact CG1-CG 3.94Å
178K97.9Very high98.5Very high133 Ų13324 Ų2458%0.57813%0.132SC*.SBendtrans-77.482.9175.3-65.9172.2-165.8154.90111.3D145 Q148 E149D145-K178 WeakPolarHBondContact OD1-CB 3.43Å; D145-K178 PolarHBondContact OD1-N 3.15Å; D145-K178 VanDerWaalsContact OD2-CD 3.31Å; D145-K178 WeakPolarHBondContact OD2-CD 3.12Å; D145-K178 WeakPolarHBondContact OD2-CE 3.47Å; D145-K178 WeakPolarHBondContact OD2-CG 3.03Å; D145-K178 IonicContact OD2-NZ 3.61Å; D145-K178 PolarHBondContact OD2-NZ 3.45Å; Q148-K178 PolarHBondContact NE2-O 3.22Å; Q148-K178 VanDerWaalsContact NE2-O 3.08Å; E149-K178 IonicContact OE1-NZ 2.79Å
179G97.3Very high98.5Very high47 Ų4724 Ų2449%0.48513%0.132SC..SBendtrans139.5-153.7175.900000110.7V177V177-G179 VanDerWaalsContact C-N 3.34Å; V177-G179 PolarHBondContact O-N 2.85Å
180T98Very high98.3Very high72 Ų7224 Ų2444%0.44213%0.133SC..  trans-126124.8179.5-54.20000109.4L155 D209L155-T180 WeakPolarHBondContact CB-O 3.5Å; T180-D209 HydrophobicContact CG2-CB 4.23Å; T180-D209 WeakPolarHBondContact CG2-OD1 3.25Å
181L98.5Very high98.1Very high0 Ų024.1 Ų24.10%013%0.134CC..BIsolated β-bridgetrans-67.7146.4174.8-61.1-179.9000110.6F144 L155 V158 L160 V177 I184 A208 D209F144-L181 HydrophobicContact CD2-CD2 4.25Å; L155-L181 HydrophobicContact CB-CD2 4.48Å; L155-L181 HydrophobicContact CD1-CD2 4.48Å; L155-L181 HydrophobicContact CD2-CD2 4Å; V158-L181 HydrophobicContact CB-CD2 4.19Å; V158-L181 HydrophobicContact CG1-CD2 3.98Å; L160-L181 HydrophobicContact CD1-CD1 3.5Å; L160-L181 VanDerWaalsContact CD1-CD1 3.5Å; L160-L181 HydrophobicContact CG-CD1 3.95Å; V177-L181 HydrophobicContact CG1-CD2 3.99Å; V177-L181 HydrophobicContact CG1-CG 3.94Å; L181-I184 HydrophobicContact CD1-CD1 4.31Å; L181-I184 HydrophobicContact CD1-CG1 4.41Å; L181-A208 HydrophobicContact CB-CB 4.02Å; L181-A208 CarbonylContact O-C 3.58Å; L181-A208 WeakPolarHBondContact O-CA 3.41Å; L181-A208 WeakPolarHBondContact O-CB 3.27Å; L181-D209 WeakPolarHBondContact O-CB 3.45Å; L181-D209 PolarHBondContact O-N 2.95Å
182G98.2Very high97.8Very high13 Ų1325.8 Ų25.813%0.13414%0.144CC..SBendtrans-66-42.4-179.900000113.7L155 V158 D209 F210L155-G182 PolarHBondContact O-N 2.9Å; V158-G182 PolarHBondContact O-N 2.95Å; G182-D209 WeakPolarHBondContact O-CB 3.37Å; G182-F210 PolarHBondContact O-N 3.33Å
183R98.6Very high97.6Very high30 Ų3030 Ų3011%0.11317%0.165CC..EExtended strand (participates in β ladder)trans-155.5142.6-179.6-171.7176.2178-178.7-3.5113.7V158 H159 L160 T185 F210 D212 G314 Y315V158-R183 PolarHBondContact O-N 2.75Å; H159-R183 CarbonylContact C-O 3.59Å; H159-R183 VanDerWaalsContact CA-O 3.3Å; H159-R183 WeakPolarHBondContact CA-O 3.33Å; H159-R183 HydrophobicContact CB-CB 4.43Å; H159-R183 PolarHBondContact CD2-O 3.2Å; L160-R183 PolarHBondContact N-O 3.45Å; R183-T185 PolarHBondContact NE-OG1 2.86Å; R183-F210 CarbonylContact C-O 3.57Å; R183-F210 VanDerWaalsContact CA-O 3.25Å; R183-F210 WeakPolarHBondContact CA-O 3.4Å; R183-F210 HydrophobicContact CG-CB 4.45Å; R183-F210 HydrophobicContact CG-CD1 3.93Å; R183-F210 WeakPolarHBondContact CG-O 3.45Å; R183-D212 IonicContact CZ-OD1 3.6Å; R183-D212 IonicContact CZ-OD2 3.43Å; R183-D212 IonicContact NE-OD1 3.22Å; R183-D212 PolarHBondContact NE-OD1 3.02Å; R183-D212 IonicContact NE-OD2 2.77Å; R183-D212 IonicContact NH2-OD1 2.72Å; R183-D212 PolarHBondContact NH2-OD1 3.28Å; R183-D212 IonicContact NH2-OD2 3.14Å; R183-D212 PolarHBondContact NH2-OD2 3.36Å; R183-G314 PolarHBondContact NH2-O 2.99Å; R183-Y315 PolarHBondContact NH1-O 3.27Å
184I98.9Very high97.5Very high0 Ų030.2 Ų30.20%017%0.166CC..EExtended strand (participates in β ladder)trans-121.7130.9162.5-63165.3000108.9L160 A170 L181 L203 D207 A208 F210 V211 D212L160-I184 HydrophobicContact CB-CG1 4.13Å; L160-I184 HydrophobicContact CD1-CG1 4.27Å; L160-I184 HydrophobicContact CG-CG1 4.29Å; L160-I184 CarbonylContact O-C 3.45Å; L160-I184 WeakPolarHBondContact O-CA 3.29Å; A170-I184 HydrophobicContact CB-CG2 3.8Å; A170-I184 WeakPolarHBondContact O-CD1 3.38Å; L181-I184 HydrophobicContact CD1-CD1 4.31Å; L181-I184 HydrophobicContact CD1-CG1 4.41Å; I184-L203 HydrophobicContact CB-CD1 4.38Å; I184-L203 HydrophobicContact CD1-CD1 4.26Å; I184-L203 HydrophobicContact CG2-CD1 3.68Å; I184-L203 HydrophobicContact CG2-CD2 4.48Å; I184-D207 HydrophobicContact CD1-CB 3.7Å; I184-A208 HydrophobicContact CB-CB 4.3Å; I184-A208 HydrophobicContact CD1-CB 3.76Å; I184-A208 HydrophobicContact CG1-CB 3.75Å; I184-F210 PolarHBondContact N-O 3.21Å; I184-V211 HydrophobicContact CB-CG2 4.31Å; I184-V211 VanDerWaalsContact O-CA 3.32Å; I184-V211 WeakPolarHBondContact O-CA 3.01Å; I184-D212 PolarHBondContact O-N 3.39Å
185T98.9Very high97.3Very high0 Ų033.1 Ų33.10%018%0.178CC..EExtended strand (participates in β ladder)trans-110119.2167.9-58.60000110H159 L160 G162 R183 L187 D212 F275H159-T185 PolarHBondContact NE2-OG1 2.94Å; L160-T185 PolarHBondContact O-N 3.22Å; G162-T185 PolarHBondContact N-O 2.9Å; R183-T185 PolarHBondContact NE-OG1 2.86Å; T185-L187 HydrophobicContact CG2-CD2 3.79Å; T185-L187 HydrophobicContact CG2-CG 4.35Å; T185-D212 CarbonylContact C-O 3.25Å; T185-D212 VanDerWaalsContact CA-O 3.24Å; T185-D212 WeakPolarHBondContact CA-O 3.49Å; T185-D212 PolarHBondContact OG1-OD1 3.35Å; T185-D212 PolarHBondContact OG1-OD2 3.13Å; T185-F275 HydrophobicContact CG2-CD2 3.9Å; T185-F275 HydrophobicContact CG2-CE2 3.66Å
186G98.8Very high97.1Very high0 Ų033.2 Ų33.20%019%0.191CC..EExtended strand (participates in β ladder)trans-91.2116.4172.100000111.4D212 V213 L214G186-D212 PolarHBondContact N-O 3.42Å; G186-V213 WeakPolarHBondContact O-CA 3.15Å; G186-L214 PolarHBondContact O-N 3.13Å
187L98.6Very high96.9Very high0 Ų029.6 Ų29.60%018%0.181CC..EExtended strand (participates in β ladder)trans-100101.4176.3-56.6178.1000109L100 I161 G162 Y163 S164 T185 L214 A271 V272 F275L100-L187 HydrophobicContact CD2-CD1 4.31Å; I161-L187 HydrophobicContact CG2-CD1 3.53Å; I161-L187 HydrophobicContact CG2-CG 4.12Å; G162-L187 PolarHBondContact O-N 2.89Å; Y163-L187 WeakPolarHBondContact CA-O 3.37Å; Y163-L187 HydrophobicContact CD2-CB 4.2Å; Y163-L187 WeakPolarHBondContact CD2-O 3.49Å; S164-L187 PolarHBondContact N-O 3.33Å; T185-L187 HydrophobicContact CG2-CD2 3.79Å; T185-L187 HydrophobicContact CG2-CG 4.35Å; L187-L214 HydrophobicContact CD2-CD1 3.92Å; L187-L214 HydrophobicContact CD2-CG 4.38Å; L187-A271 HydrophobicContact CB-CB 3.99Å; L187-V272 HydrophobicContact CD1-CG2 4.21Å; L187-F275 HydrophobicContact CD1-CB 4.39Å; L187-F275 HydrophobicContact CD2-CB 3.76Å; L187-F275 HydrophobicContact CD2-CD2 3.91Å; L187-F275 HydrophobicContact CD2-CG 4Å
188D97.8Very high96.7Very high0 Ų034.5 Ų34.50%020%0.203CC..SBendtrans41.566.2-173.5-149.437.4000112.9S164 L214 H215 T216 Y217 H268 A271S164-D188 WeakPolarHBondContact CA-O 3.41Å; D188-L214 WeakPolarHBondContact CA-O 3.3Å; D188-L214 PolarHBondContact N-O 3.4Å; D188-H215 WeakPolarHBondContact OD1-CA 3.42Å; D188-T216 PolarHBondContact OD1-N 2.66Å; D188-T216 PolarHBondContact OD2-OG1 3.01Å; D188-Y217 PolarHBondContact OD1-N 3.19Å; D188-Y217 VanDerWaalsContact OD1-N 3.12Å; D188-Y217 VanDerWaalsContact OD2-CB 3.26Å; D188-Y217 WeakPolarHBondContact OD2-CB 3.4Å; D188-Y217 PolarHBondContact OD2-N 3.21Å; D188-H268 PolarHBondContact O-CE1 2.88Å; D188-H268 WeakPolarHBondContact OD2-CA 3.44Å; D188-H268 IonicContact OD2-CE1 2.84Å; D188-H268 IonicContact OD2-CG 2.87Å; D188-H268 IonicContact OD2-ND1 3.26Å; D188-H268 PolarHBondContact OD2-ND1 2.87Å; D188-A271 HydrophobicContact CB-CB 3.78Å
189P98.4Very high96.5Very high0 Ų031.6 Ų31.60%019%0.192CC..  trans-55.4146-178.5-24.837.2000111.6A167 G191 L203 V213 G227 I228 I232A167-P189 HydrophobicContact CB-CB 3.64Å; A167-P189 HydrophobicContact CB-CG 3.62Å; P189-G191 PolarHBondContact O-N 2.89Å; P189-L203 HydrophobicContact CG-CD2 4.29Å; P189-V213 HydrophobicContact CG-CG1 3.6Å; P189-G227 CarbonylContact O-C 3.54Å; P189-G227 WeakPolarHBondContact O-CA 3.07Å; P189-I228 HydrophobicContact CB-CG2 3.91Å; P189-I228 HydrophobicContact CG-CG2 4.43Å; P189-I228 PolarHBondContact O-N 3.08Å; P189-I232 HydrophobicContact CB-CD1 3.92Å; P189-I232 HydrophobicContact CG-CD1 3.98Å
190A96.4Very high96.4Very high1 Ų135.2 Ų35.21%0.00820%0.196CC..BIsolated β-bridgetrans-65.5134.5-174.800000112.2S164 L165 H168 F194S164-A190 PolarHBondContact O-N 2.96Å; L165-A190 HydrophobicContact CD2-CB 3.75Å; L165-A190 HydrophobicContact CG-CB 4.48Å; H168-A190 PolarHBondContact NE2-N 3.48Å; H168-A190 PolarHBondContact NE2-O 3.44Å; A190-F194 HydrophobicContact CB-CD2 4.28Å; A190-F194 WeakPolarHBondContact O-CB 3.44Å
191G94.4Very high96.3Very high2 Ų236.2 Ų36.22%0.02119%0.194CC..  trans-81.9-50.517600000114.2P189 M193 F194 E195 I226P189-G191 PolarHBondContact O-N 2.89Å; G191-M193 PolarHBondContact O-N 2.8Å; G191-F194 PolarHBondContact O-N 2.97Å; G191-E195 WeakPolarHBondContact O-CB 2.99Å; G191-E195 PolarHBondContact O-N 3.09Å; G191-I226 PolarHBondContact N-O 3.05Å
192P92.4Very high96.3Very high34 Ų3437 Ų3722%0.22120%0.197CC..THydrogen-bonded Turntrans-61.7133.7-173.2-18.630000111.2Y126 F194 V224 S225 I226Y126-P192 HydrophobicContact CE1-CB 3.71Å; Y126-P192 HydrophobicContact CE1-CG 4.41Å; Y126-P192 WeakPolarHBondContact OH-CD 3.05Å; Y126-P192 PolarHBondContact OH-O 3.09Å; P192-F194 WeakPolarHBondContact O-CD2 3.36Å; P192-F194 PolarHBondContact O-N 3.08Å; P192-V224 HydrophobicContact CB-CG1 4.13Å; P192-V224 HydrophobicContact CG-CG1 3.66Å; P192-S225 VanDerWaalsContact CD-O 3.28Å; P192-S225 WeakPolarHBondContact CD-O 3.32Å; P192-I226 WeakPolarHBondContact CD-O 3.5Å
193M93.9Very high96.3Very high99 Ų9936.3 Ų36.349%0.48819%0.191SC..THydrogen-bonded Turntrans64.84-174.8-53.2178.270.300116.3Y126 P127 V130 G191 V197Y126-M193 HydrophobicContact CD1-SD 4.47Å; Y126-M193 HydrophobicContact CE1-SD 4.35Å; P127-M193 HydrophobicContact CB-CE 4.31Å; P127-M193 HydrophobicContact CB-SD 4.02Å; P127-M193 HydrophobicContact CG-SD 4.35Å; V130-M193 HydrophobicContact CB-CE 4.5Å; V130-M193 HydrophobicContact CB-SD 4.14Å; V130-M193 HydrophobicContact CG1-CB 4Å; V130-M193 HydrophobicContact CG1-CE 4.07Å; V130-M193 HydrophobicContact CG1-SD 4.1Å; V130-M193 HydrophobicContact CG2-CB 4.46Å; V130-M193 HydrophobicContact CG2-SD 4.06Å; G191-M193 PolarHBondContact O-N 2.8Å; M193-V197 WeakPolarHBondContact O-CG2 3.09Å
194F96.5Very high96.2Very high5 Ų535.1 Ų35.12%0.02219%0.187CC..THydrogen-bonded Turntrans-123.9-24174.2-66.6-75.5000113.9V130 T133 L165 H168 F172 A190 G191 P192 G196 V197 K201 R202 I228V130-F194 HydrophobicContact CG1-CE2 3.98Å; V130-F194 HydrophobicContact CG1-CZ 3.88Å; V130-F194 HydrophobicContact CG2-CE2 4.07Å; T133-F194 HydrophobicContact CG2-CZ 4.34Å; L165-F194 HydrophobicContact CD2-CD2 4.49Å; L165-F194 HydrophobicContact CD2-CE2 3.58Å; L165-F194 HydrophobicContact CD2-CZ 4.34Å; H168-F194 HydrophobicContact CB-CD1 4.36Å; H168-F194 HydrophobicContact CB-CE1 3.76Å; H168-F194 HydrophobicContact CB-CE2 4.44Å; H168-F194 HydrophobicContact CB-CZ 3.8Å; H168-F194 AromaticContact CD2-CD2 3.64Å; H168-F194 AromaticContact CD2-CE2 3.65Å; H168-F194 AromaticContact CD2-CG 3.9Å; H168-F194 AromaticContact CD2-CZ 3.9Å; H168-F194 AromaticContact CE1-CD1 3.83Å; H168-F194 AromaticContact CE1-CG 3.55Å; H168-F194 AromaticContact CG-CD1 3.75Å; H168-F194 AromaticContact CG-CE1 3.61Å; H168-F194 AromaticContact CG-CE2 3.96Å; H168-F194 AromaticContact CG-CG 3.95Å; H168-F194 AromaticContact CG-CZ 3.72Å; H168-F194 AromaticContact ND1-CD1 3.51Å; H168-F194 AromaticContact ND1-CE1 3.82Å; H168-F194 AromaticContact ND1-CG 3.72Å; H168-F194 AromaticContact NE2-CD2 3.67Å; H168-F194 AromaticContact NE2-CG 3.7Å; F172-F194 HydrophobicContact CE2-CE1 4.44Å; A190-F194 HydrophobicContact CB-CD2 4.28Å; A190-F194 WeakPolarHBondContact O-CB 3.44Å; G191-F194 PolarHBondContact O-N 2.97Å; P192-F194 WeakPolarHBondContact O-CD2 3.36Å; P192-F194 PolarHBondContact O-N 3.08Å; F194-G196 PolarHBondContact O-N 3.21Å; F194-V197 WeakPolarHBondContact O-CB 3.24Å; F194-V197 PolarHBondContact O-N 3.22Å; F194-K201 WeakPolarHBondContact CD1-O 3.48Å; F194-K201 WeakPolarHBondContact CE1-O 3.47Å; F194-R202 HydrophobicContact CD1-CB 3.84Å; F194-I228 HydrophobicContact CB-CD1 4.31Å
195E94.8Very high96.1Very high69 Ų6935.4 Ų35.432%0.32219%0.189SC..THydrogen-bonded Turntrans-60131.6175-172.365.8-104.500111G191 V197 I228 Q229 Q230G191-E195 WeakPolarHBondContact O-CB 2.99Å; G191-E195 PolarHBondContact O-N 3.09Å; E195-V197 PolarHBondContact O-N 3.44Å; E195-V197 VanDerWaalsContact O-N 3.08Å; E195-I228 HydrophobicContact CB-CG1 4.45Å; E195-I228 WeakPolarHBondContact OE2-CG1 3.27Å; E195-Q229 WeakPolarHBondContact OE2-CA 3.17Å; E195-Q229 WeakPolarHBondContact OE2-CB 3.13Å; E195-Q229 PolarHBondContact OE2-N 2.78Å; E195-Q230 WeakPolarHBondContact OE1-CB 3.02Å; E195-Q230 WeakPolarHBondContact OE1-CG 3.42Å; E195-Q230 PolarHBondContact OE1-N 3.12Å; E195-Q230 PolarHBondContact OE1-OE1 3.48Å
196G93.3Very high96Very high62 Ų6239.5 Ų39.564%0.63921%0.211SC*.THydrogen-bonded Turntrans67.8-0.6-177.600000115.7F194F194-G196 PolarHBondContact O-N 3.21Å
197V94.1Very high95.9Very high43 Ų4339.8 Ų39.826%0.26121%0.212SC..  trans-77150.2177.6-1760000110.6M193 F194 E195 K201 R202M193-V197 WeakPolarHBondContact O-CG2 3.09Å; F194-V197 WeakPolarHBondContact O-CB 3.24Å; F194-V197 PolarHBondContact O-N 3.22Å; E195-V197 PolarHBondContact O-N 3.44Å; E195-V197 VanDerWaalsContact O-N 3.08Å; V197-K201 HydrophobicContact CG1-CB 3.58Å; V197-K201 HydrophobicContact CG1-CD 4.04Å; V197-K201 HydrophobicContact CG1-CG 4.45Å; V197-R202 PolarHBondContact O-NE 3.01Å
198E95.4Very high95.9Very high114 Ų11440.1 Ų40.153%0.53322%0.215SC..  trans-51.6145.6176.1-63.6172.4155.400112.6Q200 K201E198-Q200 PolarHBondContact O-N 2.83Å; E198-Q200 VanDerWaalsContact O-N 3.16Å; E198-K201 PolarHBondContact O-N 3.45Å; E198-K201 WeakPolarHBondContact OE2-CE 3.47Å; E198-K201 IonicContact OE2-NZ 3.9Å; E198-K201 PolarHBondContact OE2-NZ 3.28Å
199E94Very high95.9Very high73 Ų7343.7 Ų43.734%0.34123%0.234SC..G310 helixtrans-56.4-34.3-174.9-74.3177.1168.900113.3K201 R202E199-K201 PolarHBondContact O-N 2.63Å; E199-R202 VanDerWaalsContact CG-NH2 3.29Å; E199-R202 PolarHBondContact O-N 3.41Å
200Q94.2Very high95.8Very high122 Ų12244.4 Ų44.457%0.5724%0.237SC*.G310 helixtrans-70-13.1-179.5-58.879.26.700113.7F172 E198F172-Q200 WeakPolarHBondContact CE1-O 3.33Å; E198-Q200 PolarHBondContact O-N 2.83Å; E198-Q200 VanDerWaalsContact O-N 3.16Å
201K95.9Very high95.9Very high93 Ų9344.4 Ų44.440%0.40424%0.237SC..G310 helixtrans-110.916.4-174.8-66.9174.9-176.4153.20112.5F172 F194 V197 E198 E199F172-K201 VanDerWaalsContact CZ-C 3.49Å; F172-K201 WeakPolarHBondContact CZ-O 3.25Å; F194-K201 WeakPolarHBondContact CD1-O 3.48Å; F194-K201 WeakPolarHBondContact CE1-O 3.47Å; V197-K201 HydrophobicContact CG1-CB 3.58Å; V197-K201 HydrophobicContact CG1-CD 4.04Å; V197-K201 HydrophobicContact CG1-CG 4.45Å; E198-K201 PolarHBondContact O-N 3.45Å; E198-K201 WeakPolarHBondContact OE2-CE 3.47Å; E198-K201 IonicContact OE2-NZ 3.9Å; E198-K201 PolarHBondContact OE2-NZ 3.28Å; E199-K201 PolarHBondContact O-N 2.63Å
202R97.9Very high96.1Very high16 Ų1644.3 Ų44.36%0.0624%0.236CC..SBendtrans-159.3178.5178.655169.9175.478.5-4.1109.7H168 F194 V197 E199 S204H168-R202 WeakPolarHBondContact ND1-CB 3.42Å; F194-R202 HydrophobicContact CD1-CB 3.84Å; V197-R202 PolarHBondContact O-NE 3.01Å; E199-R202 VanDerWaalsContact CG-NH2 3.29Å; E199-R202 PolarHBondContact O-N 3.41Å; R202-S204 PolarHBondContact O-N 3.26Å
203L98.6Very high96.3Very high0 Ų042.7 Ų42.70%023%0.225CC..  trans-59.2134.6164.217667.2000110.4A167 H168 I184 P189 D207 V211 V213 I232A167-L203 HydrophobicContact CB-CD2 4.25Å; H168-L203 PolarHBondContact ND1-N 3.45Å; I184-L203 HydrophobicContact CB-CD1 4.38Å; I184-L203 HydrophobicContact CD1-CD1 4.26Å; I184-L203 HydrophobicContact CG2-CD1 3.68Å; I184-L203 HydrophobicContact CG2-CD2 4.48Å; P189-L203 HydrophobicContact CG-CD2 4.29Å; L203-D207 VanDerWaalsContact CA-OD2 3.29Å; L203-D207 WeakPolarHBondContact CA-OD2 3.47Å; L203-V211 HydrophobicContact CD1-CG1 3.87Å; L203-V211 HydrophobicContact CD2-CG1 4.18Å; L203-V211 HydrophobicContact CG-CG1 4.12Å; L203-V213 HydrophobicContact CD2-CG2 4.2Å; L203-I232 HydrophobicContact CB-CD1 3.98Å; L203-I232 HydrophobicContact CD2-CD1 4.07Å; L203-I232 HydrophobicContact CG-CD1 4.2Å
204S97.4Very high96.6Very high4 Ų438 Ų383%0.02820%0.202CC..  trans-140.8162-179.395.20000111.4R202 D206 D207 V211 I232R202-S204 PolarHBondContact O-N 3.26Å; S204-D206 PolarHBondContact O-N 3.41Å; S204-D206 PolarHBondContact OG-N 2.9Å; S204-D206 VanDerWaalsContact OG-N 3.15Å; S204-D207 PolarHBondContact N-OD2 3.14Å; S204-D207 PolarHBondContact O-N 2.86Å; S204-D207 PolarHBondContact OG-OD1 3.03Å; S204-V211 WeakPolarHBondContact O-CG2 3.38Å; S204-I232 CarbonylContact C-O 3.56Å; S204-I232 VanDerWaalsContact C-O 3.31Å; S204-I232 WeakPolarHBondContact CA-O 3.33Å
205P96.4Very high96.6Very high7 Ų737.7 Ų37.75%0.04520%0.201CC..THydrogen-bonded Turntrans-65.8-14.5175.9-17.430.6000114.5I232 N325P205-I232 VanDerWaalsContact CD-O 3.29Å; P205-I232 WeakPolarHBondContact CD-O 3.35Å; P205-N325 WeakPolarHBondContact CG-OD1 3.19Å
206D95.8Very high96.6Very high86 Ų8634.4 Ų34.446%0.4619%0.186SC..THydrogen-bonded Turntrans-88.6-7.9-178.5-74.9-41000112.9S204 A208 R324S204-D206 PolarHBondContact O-N 3.41Å; S204-D206 PolarHBondContact OG-N 2.9Å; S204-D206 VanDerWaalsContact OG-N 3.15Å; D206-A208 VanDerWaalsContact C-N 3.27Å; D206-A208 PolarHBondContact O-N 3.41Å; D206-R324 VanDerWaalsContact CG-NH1 3.34Å; D206-R324 IonicContact OD1-CZ 3.04Å; D206-R324 IonicContact OD1-NH1 3.67Å; D206-R324 PolarHBondContact OD1-NH1 2.79Å; D206-R324 IonicContact OD1-NH2 4Å; D206-R324 PolarHBondContact OD1-NH2 2.05Å; D206-R324 IonicContact OD2-CZ 2.8Å; D206-R324 IonicContact OD2-NH1 2.58Å; D206-R324 PolarHBondContact OD2-NH1 2.86Å; D206-R324 IonicContact OD2-NH2 3.79Å
207D98.2Very high96.5Very high6 Ų632.4 Ų32.43%0.03216%0.159CC..SBendtrans-77.3-12.7-175.3-53.7-8.2000112.8G171 G174 T175 I184 L203 S204G171-D207 WeakPolarHBondContact CA-OD2 3.35Å; G174-D207 CarbonylContact C-O 3.59Å; G174-D207 WeakPolarHBondContact CA-O 3.25Å; T175-D207 PolarHBondContact OG1-OD1 3.22Å; I184-D207 HydrophobicContact CD1-CB 3.7Å; L203-D207 VanDerWaalsContact CA-OD2 3.29Å; L203-D207 WeakPolarHBondContact CA-OD2 3.47Å; S204-D207 PolarHBondContact N-OD2 3.14Å; S204-D207 PolarHBondContact O-N 2.86Å; S204-D207 PolarHBondContact OG-OD1 3.03Å
208A98Very high96.3Very high6 Ų631.2 Ų31.25%0.0515%0.152CC..BIsolated β-bridgetrans-155.7168.1175.600000111.8L181 I184 D206 F210 V211L181-A208 HydrophobicContact CB-CB 4.02Å; L181-A208 CarbonylContact O-C 3.58Å; L181-A208 WeakPolarHBondContact O-CA 3.41Å; L181-A208 WeakPolarHBondContact O-CB 3.27Å; I184-A208 HydrophobicContact CB-CB 4.3Å; I184-A208 HydrophobicContact CD1-CB 3.76Å; I184-A208 HydrophobicContact CG1-CB 3.75Å; D206-A208 VanDerWaalsContact C-N 3.27Å; D206-A208 PolarHBondContact O-N 3.41Å; A208-F210 PolarHBondContact O-N 3.31Å; A208-V211 HydrophobicContact CB-CG2 3.98Å
209D96.9Very high95.7Very high76 Ų7631.1 Ų31.141%0.40615%0.146SC..SBendtrans-60.4-28.3171.2-90.7-25.3000112T180 L181 G182 K319T180-D209 HydrophobicContact CG2-CB 4.23Å; T180-D209 WeakPolarHBondContact CG2-OD1 3.25Å; L181-D209 WeakPolarHBondContact O-CB 3.45Å; L181-D209 PolarHBondContact O-N 2.95Å; G182-D209 WeakPolarHBondContact O-CB 3.37Å; D209-K319 WeakPolarHBondContact O-CD 3.44Å; D209-K319 WeakPolarHBondContact O-CE 3.31Å; D209-K319 PolarHBondContact O-NZ 3.41Å
210F97.4Very high94.9Very high15 Ų1533 Ų337%0.06616%0.155CC..  trans-147.6122.1173.4178.2-138.3000111.2G182 R183 I184 A208 D212 D234 I235 A317 R318 K319G182-F210 PolarHBondContact O-N 3.33Å; R183-F210 CarbonylContact C-O 3.57Å; R183-F210 VanDerWaalsContact CA-O 3.25Å; R183-F210 WeakPolarHBondContact CA-O 3.4Å; R183-F210 HydrophobicContact CG-CB 4.45Å; R183-F210 HydrophobicContact CG-CD1 3.93Å; R183-F210 WeakPolarHBondContact CG-O 3.45Å; I184-F210 PolarHBondContact N-O 3.21Å; A208-F210 PolarHBondContact O-N 3.31Å; F210-D212 HydrophobicContact CE1-CB 4.16Å; F210-D212 HydrophobicContact CE2-CB 4.16Å; F210-D212 HydrophobicContact CZ-CB 3.71Å; F210-D234 WeakPolarHBondContact CA-OD2 3.3Å; F210-D234 HydrophobicContact CD2-CB 4Å; F210-D234 HydrophobicContact CE2-CB 4.11Å; F210-I235 HydrophobicContact CE2-CD1 4.13Å; F210-I235 HydrophobicContact CE2-CG1 4.02Å; F210-I235 HydrophobicContact CE2-CG2 4.33Å; F210-I235 HydrophobicContact CZ-CD1 3.71Å; F210-I235 HydrophobicContact CZ-CG1 4.06Å; F210-A317 HydrophobicContact CE1-CB 4.46Å; F210-A317 HydrophobicContact CZ-CB 4.32Å; F210-R318 VanDerWaalsContact CZ-C 3.5Å; F210-K319 HydrophobicContact CB-CB 4.28Å; F210-K319 HydrophobicContact CB-CD 4.43Å; F210-K319 HydrophobicContact CD2-CB 3.66Å; F210-K319 HydrophobicContact CD2-CG 3.9Å; F210-K319 HydrophobicContact CE2-CB 4.11Å; F210-K319 HydrophobicContact CG-CB 3.9Å; F210-K319 HydrophobicContact CG-CG 4.41Å
211V98Very high93.3Very high0 Ų029 Ų290%014%0.142CC..EExtended strand (participates in β ladder)trans-114.6117.3175.5-174.80000110.4I184 L203 S204 A208 V213 D234 I235I184-V211 HydrophobicContact CB-CG2 4.31Å; I184-V211 VanDerWaalsContact O-CA 3.32Å; I184-V211 WeakPolarHBondContact O-CA 3.01Å; L203-V211 HydrophobicContact CD1-CG1 3.87Å; L203-V211 HydrophobicContact CD2-CG1 4.18Å; L203-V211 HydrophobicContact CG-CG1 4.12Å; S204-V211 WeakPolarHBondContact O-CG2 3.38Å; A208-V211 HydrophobicContact CB-CG2 3.98Å; V211-V213 HydrophobicContact CG1-CG2 4.12Å; V211-D234 PolarHBondContact N-OD2 2.96Å; V211-D234 WeakPolarHBondContact O-CB 3.39Å; V211-D234 PolarHBondContact O-N 3.36Å; V211-I235 PolarHBondContact O-N 3.36Å
212D98Very high91.5Very high0 Ų031.5 Ų31.50%016%0.16CC..EExtended strand (participates in β ladder)trans-118.9132.6175.268.2-63.9000112.6R183 I184 T185 G186 F210 I235R183-D212 IonicContact CZ-OD1 3.6Å; R183-D212 IonicContact CZ-OD2 3.43Å; R183-D212 IonicContact NE-OD1 3.22Å; R183-D212 PolarHBondContact NE-OD1 3.02Å; R183-D212 IonicContact NE-OD2 2.77Å; R183-D212 IonicContact NH2-OD1 2.72Å; R183-D212 PolarHBondContact NH2-OD1 3.28Å; R183-D212 IonicContact NH2-OD2 3.14Å; R183-D212 PolarHBondContact NH2-OD2 3.36Å; I184-D212 PolarHBondContact O-N 3.39Å; T185-D212 CarbonylContact C-O 3.25Å; T185-D212 VanDerWaalsContact CA-O 3.24Å; T185-D212 WeakPolarHBondContact CA-O 3.49Å; T185-D212 PolarHBondContact OG1-OD1 3.35Å; T185-D212 PolarHBondContact OG1-OD2 3.13Å; G186-D212 PolarHBondContact N-O 3.42Å; F210-D212 HydrophobicContact CE1-CB 4.16Å; F210-D212 HydrophobicContact CE2-CB 4.16Å; F210-D212 HydrophobicContact CZ-CB 3.71Å; D212-I235 HydrophobicContact CB-CD1 3.75Å; D212-I235 HydrophobicContact CB-CG1 3.47Å; D212-I235 VanDerWaalsContact CB-CG1 3.47Å
213V98.5Very high89.7Confident0 Ų033.5 Ų33.50%019%0.185CC..EExtended strand (participates in β ladder)trans-126.2132-170.5-169.20000110.7G186 P189 L203 V211 H215 I232 I235 I237G186-V213 WeakPolarHBondContact O-CA 3.15Å; P189-V213 HydrophobicContact CG-CG1 3.6Å; L203-V213 HydrophobicContact CD2-CG2 4.2Å; V211-V213 HydrophobicContact CG1-CG2 4.12Å; V213-H215 VanDerWaalsContact CG1-NE2 3.34Å; V213-H215 WeakPolarHBondContact CG1-NE2 3.28Å; V213-I232 HydrophobicContact CG1-CG1 4.34Å; V213-I232 HydrophobicContact CG2-CG1 4.08Å; V213-I235 PolarHBondContact N-O 2.76Å; V213-I237 PolarHBondContact O-N 2.76Å
214L98.4Very high88.1Confident0 Ų035.4 Ų35.40%020%0.197CC..EExtended strand (participates in β ladder)trans-102.8118.4170-63.4-175000108.9G186 L187 D188 I237 A271 L274 F275G186-L214 PolarHBondContact O-N 3.13Å; L187-L214 HydrophobicContact CD2-CD1 3.92Å; L187-L214 HydrophobicContact CD2-CG 4.38Å; D188-L214 WeakPolarHBondContact CA-O 3.3Å; D188-L214 PolarHBondContact N-O 3.4Å; L214-I237 HydrophobicContact CD2-CB 3.79Å; L214-I237 HydrophobicContact CD2-CD1 3.89Å; L214-I237 HydrophobicContact CD2-CG1 4.43Å; L214-I237 HydrophobicContact CD2-CG2 4.07Å; L214-A271 HydrophobicContact CB-CB 3.98Å; L214-A271 WeakPolarHBondContact CD1-O 3.46Å; L214-L274 HydrophobicContact CD1-CB 4.17Å; L214-F275 HydrophobicContact CD1-CB 4.44Å
215H97.7Very high87.3Confident0 Ų035.7 Ų35.70%020%0.198CC..  trans-105.6107.4176.2-59-98.5000109.2D188 V213 T218 I228 Q230 D236 I237 Y238 P239 G242D188-H215 WeakPolarHBondContact OD1-CA 3.42Å; V213-H215 VanDerWaalsContact CG1-NE2 3.34Å; V213-H215 WeakPolarHBondContact CG1-NE2 3.28Å; H215-T218 HydrophobicContact CB-CG2 3.66Å; H215-I228 PolarHBondContact ND1-O 2.69Å; H215-Q230 PolarHBondContact CE1-O 3.12Å; H215-D236 IonicContact NE2-OD1 3.42Å; H215-D236 PolarHBondContact NE2-OD1 2.81Å; H215-I237 PolarHBondContact N-O 3.06Å; H215-Y238 HydrophobicContact CB-CD1 3.49Å; H215-Y238 VanDerWaalsContact CB-CD1 3.49Å; H215-Y238 HydrophobicContact CB-CE1 3.63Å; H215-Y238 HydrophobicContact CB-CG 4.16Å; H215-Y238 AromaticContact CD2-CE1 3.83Å; H215-Y238 AromaticContact CD2-CZ 3.72Å; H215-Y238 AromaticContact CG-CD1 3.92Å; H215-Y238 AromaticContact CG-CE1 3.56Å; H215-Y238 AromaticContact CG-CZ 3.92Å; H215-Y238 AromaticContact ND1-CE1 3.98Å; H215-Y238 AromaticContact NE2-CZ 3.96Å; H215-P239 VanDerWaalsContact O-CD 3.23Å; H215-P239 WeakPolarHBondContact O-CD 3.21Å; H215-G242 VanDerWaalsContact O-CA 3.32Å; H215-G242 WeakPolarHBondContact O-CA 3.29Å
216T95.3Very high86.9Confident0 Ų037.2 Ų37.20%021%0.206CC..  trans-115.8-14.8-175.350.80000113.9D188 P239 G242 Q245 E267 H268 R270 A271 L274D188-T216 PolarHBondContact OD1-N 2.66Å; D188-T216 PolarHBondContact OD2-OG1 3.01Å; T216-P239 HydrophobicContact CG2-CB 4.39Å; T216-P239 HydrophobicContact CG2-CG 3.92Å; T216-G242 CarbonylContact C-O 3.52Å; T216-G242 VanDerWaalsContact C-O 3.25Å; T216-Q245 WeakPolarHBondContact O-CG 3.17Å; T216-Q245 PolarHBondContact O-NE2 3.38Å; T216-E267 VanDerWaalsContact CB-O 3.23Å; T216-E267 WeakPolarHBondContact CB-O 3.22Å; T216-E267 PolarHBondContact OG1-O 3.36Å; T216-H268 PolarHBondContact OG1-O 3.17Å; T216-R270 HydrophobicContact CG2-CB 4.23Å; T216-R270 HydrophobicContact CG2-CG 4.14Å; T216-A271 HydrophobicContact CG2-CB 4.05Å; T216-A271 WeakPolarHBondContact OG1-CB 3.38Å; T216-A271 PolarHBondContact OG1-N 3.02Å; T216-L274 HydrophobicContact CG2-CD1 3.92Å
217Y91.3Very high86.7Confident20 Ų2033.1 Ų33.18%0.07818%0.184CC..  trans-137.764.6176.7-162-167000115D188 R219 S225 I226 G227 G242 M264 E267 H268D188-Y217 PolarHBondContact OD1-N 3.19Å; D188-Y217 VanDerWaalsContact OD1-N 3.12Å; D188-Y217 VanDerWaalsContact OD2-CB 3.26Å; D188-Y217 WeakPolarHBondContact OD2-CB 3.4Å; D188-Y217 PolarHBondContact OD2-N 3.21Å; Y217-R219 HydrophobicContact CD2-CB 4.35Å; Y217-R219 HydrophobicContact CE2-CB 4.18Å; Y217-S225 PolarHBondContact O-OG 2.66Å; Y217-I226 HydrophobicContact CD1-CB 3.83Å; Y217-I226 HydrophobicContact CD1-CD1 3.74Å; Y217-I226 HydrophobicContact CD1-CG1 4.28Å; Y217-I226 HydrophobicContact CD1-CG2 4.3Å; Y217-I226 HydrophobicContact CE1-CB 4.16Å; Y217-I226 HydrophobicContact CE1-CD1 3.25Å; Y217-I226 HydrophobicContact CE1-CG1 4.08Å; Y217-I226 HydrophobicContact CG-CB 4.49Å; Y217-G227 WeakPolarHBondContact O-CA 3.47Å; Y217-G227 PolarHBondContact O-N 2.71Å; Y217-G242 CarbonylContact C-O 3.6Å; Y217-G242 WeakPolarHBondContact CA-O 3.36Å; Y217-G242 PolarHBondContact N-O 2.83Å; Y217-M264 HydrophobicContact CE1-CB 4.32Å; Y217-M264 WeakPolarHBondContact CE1-O 3.36Å; Y217-M264 HydrophobicContact CE1-SD 3.89Å; Y217-M264 PolarHBondContact OH-SD 3.04Å; Y217-E267 HydrophobicContact CD1-CB 3.84Å; Y217-E267 HydrophobicContact CD2-CB 3.79Å; Y217-E267 HydrophobicContact CD2-CG 4.25Å; Y217-E267 HydrophobicContact CE1-CB 4.33Å; Y217-E267 HydrophobicContact CE2-CB 4.34Å; Y217-E267 HydrophobicContact CE2-CG 4.48Å; Y217-E267 HydrophobicContact CG-CB 3.53Å; Y217-E267 HydrophobicContact CG-CG 4.46Å; Y217-H268 HydrophobicContact CD1-CB 4.28Å
218T89.7Confident86.6Confident18 Ų1832.9 Ų32.911%0.1118%0.183CC..  trans-91.97.5-179.373.90000113.8H215 S225 I228 Y238 G242H215-T218 HydrophobicContact CB-CG2 3.66Å; T218-S225 WeakPolarHBondContact CA-OG 3.28Å; T218-S225 PolarHBondContact O-OG 2.9Å; T218-I228 WeakPolarHBondContact CG2-O 3.39Å; T218-Y238 HydrophobicContact CG2-CD1 4.3Å; T218-Y238 HydrophobicContact CG2-CE1 4.24Å; T218-G242 PolarHBondContact N-O 3.14Å; T218-G242 PolarHBondContact OG1-O 2.82Å; T218-G242 VanDerWaalsContact OG1-O 3.11Å
219R82.4Confident86.4Confident111 Ų11135.8 Ų35.842%0.41920%0.195SC..  trans-77.9127.1-178.2177.1179.7171.6-169.2-2.8109.1Y217 A221 D243 E252Y217-R219 HydrophobicContact CD2-CB 4.35Å; Y217-R219 HydrophobicContact CE2-CB 4.18Å; R219-A221 PolarHBondContact O-N 3.33Å; R219-D243 HydrophobicContact CB-CB 4.38Å; R219-E252 IonicContact CZ-OE1 2.87Å; R219-E252 IonicContact NH1-OE1 2.63Å; R219-E252 PolarHBondContact NH1-OE1 3.33Å; R219-E252 IonicContact NH2-OE1 3.61Å
220E76.7Confident86.3Confident114 Ų11434.2 Ų34.253%0.53319%0.186SC..EExtended strand (participates in β ladder)trans-67.8122.6170.2-67.7175.3-169.100110.5Q229E220-Q229 PolarHBondContact OE1-NE2 3.28Å
221A60.9Low86.2Confident36 Ų3634.8 Ų34.830%0.29819%0.19SC..EExtended strand (participates in β ladder)trans-115.5121.6165.300000107.3R219 G223 V224R219-A221 PolarHBondContact O-N 3.33Å; A221-G223 PolarHBondContact O-N 3.34Å; A221-V224 PolarHBondContact N-O 2.86Å; A221-V224 PolarHBondContact O-N 3.24Å; A221-V224 VanDerWaalsContact O-O 3.06Å
222L58.3Low86.2Confident147 Ų14734.8 Ų34.877%0.7719%0.191SC*.THydrogen-bonded Turntrans56.835.4-178-54.1172.3000113.7L12 V224L12-L222 HydrophobicContact CD2-CD1 3.6Å; L222-V224 VanDerWaalsContact C-N 3.34Å
223G59.2Low86.1Confident57 Ų5734.8 Ų34.859%0.58819%0.191SC*.THydrogen-bonded Turntrans82.54.8177.600000115.2A221A221-G223 PolarHBondContact O-N 3.34Å
224V65.2Low86Confident41 Ų4135.6 Ų35.625%0.24820%0.195CC..EExtended strand (participates in β ladder)trans-130.5134.1177.7-177.10000110.2V15 L19 P192 A221 L222V15-V224 HydrophobicContact CG1-CG2 3.71Å; L19-V224 HydrophobicContact CD1-CG2 4.4Å; P192-V224 HydrophobicContact CB-CG1 4.13Å; P192-V224 HydrophobicContact CG-CG1 3.66Å; A221-V224 PolarHBondContact N-O 2.86Å; A221-V224 PolarHBondContact O-N 3.24Å; A221-V224 VanDerWaalsContact O-O 3.06Å; L222-V224 VanDerWaalsContact C-N 3.34Å
225S81.4Confident85.9Confident9 Ų935.6 Ų35.66%0.06320%0.195CC..EExtended strand (participates in β ladder)trans-95.4136.1170.5-178.80000109.8P192 Y217 T218 G227P192-S225 VanDerWaalsContact CD-O 3.28Å; P192-S225 WeakPolarHBondContact CD-O 3.32Å; Y217-S225 PolarHBondContact O-OG 2.66Å; T218-S225 WeakPolarHBondContact CA-OG 3.28Å; T218-S225 PolarHBondContact O-OG 2.9Å; S225-G227 WeakPolarHBondContact CB-O 3.49Å; S225-G227 PolarHBondContact OG-O 2.82Å
226I87.3Confident85.8Confident40 Ų4035.6 Ų35.621%0.20520%0.195CC..SBendtrans-72-48.8177.6-70173.2000111G191 P192 Y217 M264G191-I226 PolarHBondContact N-O 3.05Å; P192-I226 WeakPolarHBondContact CD-O 3.5Å; Y217-I226 HydrophobicContact CD1-CB 3.83Å; Y217-I226 HydrophobicContact CD1-CD1 3.74Å; Y217-I226 HydrophobicContact CD1-CG1 4.28Å; Y217-I226 HydrophobicContact CD1-CG2 4.3Å; Y217-I226 HydrophobicContact CE1-CB 4.16Å; Y217-I226 HydrophobicContact CE1-CD1 3.25Å; Y217-I226 HydrophobicContact CE1-CG1 4.08Å; Y217-I226 HydrophobicContact CG-CB 4.49Å; I226-M264 HydrophobicContact CD1-CB 3.68Å; I226-M264 HydrophobicContact CD1-CE 3.21Å; I226-M264 HydrophobicContact CD1-CG 3.95Å; I226-M264 HydrophobicContact CD1-SD 3.59Å; I226-M264 VanDerWaalsContact CD1-SD 3.59Å; I226-M264 HydrophobicContact CG1-CE 3.93Å
227G92.7Very high85.9Confident0 Ų035.6 Ų35.60%020%0.195CC..BIsolated β-bridgetrans-84.7147.9171.600000110.6P189 Y217 S225P189-G227 CarbonylContact O-C 3.54Å; P189-G227 WeakPolarHBondContact O-CA 3.07Å; Y217-G227 WeakPolarHBondContact O-CA 3.47Å; Y217-G227 PolarHBondContact O-N 2.71Å; S225-G227 WeakPolarHBondContact CB-O 3.49Å; S225-G227 PolarHBondContact OG-O 2.82Å
228I94.9Very high86.2Confident0 Ų035 Ų350%019%0.193CC..  trans-67135.2175.5-159.5171.9000110.4P189 F194 E195 H215 T218 Q230 I232P189-I228 HydrophobicContact CB-CG2 3.91Å; P189-I228 HydrophobicContact CG-CG2 4.43Å; P189-I228 PolarHBondContact O-N 3.08Å; F194-I228 HydrophobicContact CB-CD1 4.31Å; E195-I228 HydrophobicContact CB-CG1 4.45Å; E195-I228 WeakPolarHBondContact OE2-CG1 3.27Å; H215-I228 PolarHBondContact ND1-O 2.69Å; T218-I228 WeakPolarHBondContact CG2-O 3.39Å; I228-Q230 HydrophobicContact CD1-CG 3.84Å; I228-Q230 HydrophobicContact CG1-CG 3.93Å; I228-I232 HydrophobicContact CD1-CD1 4.27Å; I228-I232 HydrophobicContact CD1-CG2 3.94Å; I228-I232 HydrophobicContact CG2-CD1 3.81Å; I228-I232 HydrophobicContact CG2-CG1 4.35Å
229Q94.4Very high86.6Confident68 Ų6834.2 Ų34.232%0.31819%0.187SC..  trans-88-40.3-178-49-170.64000111.8E195 E220 Y238E195-Q229 WeakPolarHBondContact OE2-CA 3.17Å; E195-Q229 WeakPolarHBondContact OE2-CB 3.13Å; E195-Q229 PolarHBondContact OE2-N 2.78Å; E220-Q229 PolarHBondContact OE1-NE2 3.28Å; Q229-Y238 PolarHBondContact O-OH 3.47Å
230Q94.3Very high87.2Confident43 Ų4329.1 Ų29.120%0.20117%0.169CC..SBendtrans-65145.5-178.470-173.5-0.700111.5E195 H215 I228 I232E195-Q230 WeakPolarHBondContact OE1-CB 3.02Å; E195-Q230 WeakPolarHBondContact OE1-CG 3.42Å; E195-Q230 PolarHBondContact OE1-N 3.12Å; E195-Q230 PolarHBondContact OE1-OE1 3.48Å; H215-Q230 PolarHBondContact CE1-O 3.12Å; I228-Q230 HydrophobicContact CD1-CG 3.84Å; I228-Q230 HydrophobicContact CG1-CG 3.93Å; Q230-I232 HydrophobicContact CG-CG2 3.7Å; Q230-I232 PolarHBondContact O-N 3.13Å
231P96.3Very high87.9Confident26 Ų2624.2 Ų24.217%0.16915%0.149CC..  trans-69.5129.5173.430.5-33.7000109.4D236 N325 K327P231-D236 VanDerWaalsContact CA-CG 3.45Å; P231-D236 VanDerWaalsContact CA-OD1 3.24Å; P231-D236 WeakPolarHBondContact CA-OD1 3.34Å; P231-D236 HydrophobicContact CB-CB 3.95Å; P231-D236 WeakPolarHBondContact CB-OD2 3.29Å; P231-N325 HydrophobicContact CB-CB 4.02Å; P231-N325 HydrophobicContact CG-CB 4.08Å; P231-K327 HydrophobicContact CB-CG 4.36Å; P231-K327 VanDerWaalsContact CG-CE 3.49Å
232I96.8Very high89.2Confident1 Ų122.5 Ų22.51%0.00513%0.134CC..  trans-130.56.6-175.663.3169.1000113.8P189 L203 S204 P205 V213 I228 Q230 D236P189-I232 HydrophobicContact CB-CD1 3.92Å; P189-I232 HydrophobicContact CG-CD1 3.98Å; L203-I232 HydrophobicContact CB-CD1 3.98Å; L203-I232 HydrophobicContact CD2-CD1 4.07Å; L203-I232 HydrophobicContact CG-CD1 4.2Å; S204-I232 CarbonylContact C-O 3.56Å; S204-I232 VanDerWaalsContact C-O 3.31Å; S204-I232 WeakPolarHBondContact CA-O 3.33Å; P205-I232 VanDerWaalsContact CD-O 3.29Å; P205-I232 WeakPolarHBondContact CD-O 3.35Å; V213-I232 HydrophobicContact CG1-CG1 4.34Å; V213-I232 HydrophobicContact CG2-CG1 4.08Å; I228-I232 HydrophobicContact CD1-CD1 4.27Å; I228-I232 HydrophobicContact CD1-CG2 3.94Å; I228-I232 HydrophobicContact CG2-CD1 3.81Å; I228-I232 HydrophobicContact CG2-CG1 4.35Å; Q230-I232 HydrophobicContact CG-CG2 3.7Å; Q230-I232 PolarHBondContact O-N 3.13Å; I232-D236 PolarHBondContact N-OD1 2.84Å
233G96.6Very high90.4Very high0 Ų018 Ų180%011%0.111CC..SBendtrans-119.3-177.9174.300000114.8I235 D236 N325G233-I235 VanDerWaalsContact C-N 3.26Å; G233-D236 PolarHBondContact N-OD1 3.41Å; G233-N325 WeakPolarHBondContact O-CA 3.41Å; G233-N325 PolarHBondContact O-N 3.25Å; G233-N325 VanDerWaalsContact O-N 3.13Å; G233-N325 PolarHBondContact O-OD1 3.07Å; G233-N325 VanDerWaalsContact O-OD1 3.07Å
234D95.8Very high91.5Very high16 Ų1617.6 Ų17.69%0.08610%0.097CC..SBendtrans-63.5-40.2164.7-73.5-65.8000110.6F210 V211 N325 S326F210-D234 WeakPolarHBondContact CA-OD2 3.3Å; F210-D234 HydrophobicContact CD2-CB 4Å; F210-D234 HydrophobicContact CE2-CB 4.11Å; V211-D234 PolarHBondContact N-OD2 2.96Å; V211-D234 WeakPolarHBondContact O-CB 3.39Å; V211-D234 PolarHBondContact O-N 3.36Å; D234-N325 PolarHBondContact O-N 2.81Å; D234-S326 PolarHBondContact O-N 2.81Å; D234-S326 VanDerWaalsContact O-N 3.12Å
235I95.6Very high92.7Very high0 Ų015.7 Ų15.70%09%0.086CC..EExtended strand (participates in β ladder)trans-128.5134.8173.670.9174.2000110.4F210 V211 D212 V213 G233 I237 A317 M320F210-I235 HydrophobicContact CE2-CD1 4.13Å; F210-I235 HydrophobicContact CE2-CG1 4.02Å; F210-I235 HydrophobicContact CE2-CG2 4.33Å; F210-I235 HydrophobicContact CZ-CD1 3.71Å; F210-I235 HydrophobicContact CZ-CG1 4.06Å; V211-I235 PolarHBondContact O-N 3.36Å; D212-I235 HydrophobicContact CB-CD1 3.75Å; D212-I235 HydrophobicContact CB-CG1 3.47Å; D212-I235 VanDerWaalsContact CB-CG1 3.47Å; V213-I235 PolarHBondContact N-O 2.76Å; G233-I235 VanDerWaalsContact C-N 3.26Å; I235-I237 HydrophobicContact CD1-CD1 4.11Å; I235-A317 HydrophobicContact CD1-CB 3.79Å; I235-M320 HydrophobicContact CG2-CE 3.81Å; I235-M320 HydrophobicContact CG2-CG 4.16Å
236D97.2Very high93.1Very high0 Ų017.3 Ų17.30%010%0.096CC..EExtended strand (participates in β ladder)trans-125.7108.9-178.5-56.5-89.4000107.4H215 P231 I232 G233 Y238 S326 K327 M328H215-D236 IonicContact NE2-OD1 3.42Å; H215-D236 PolarHBondContact NE2-OD1 2.81Å; P231-D236 VanDerWaalsContact CA-CG 3.45Å; P231-D236 VanDerWaalsContact CA-OD1 3.24Å; P231-D236 WeakPolarHBondContact CA-OD1 3.34Å; P231-D236 HydrophobicContact CB-CB 3.95Å; P231-D236 WeakPolarHBondContact CB-OD2 3.29Å; I232-D236 PolarHBondContact N-OD1 2.84Å; G233-D236 PolarHBondContact N-OD1 3.41Å; D236-Y238 HydrophobicContact CB-CE2 3.67Å; D236-Y238 WeakPolarHBondContact O-CD2 3.11Å; D236-S326 PolarHBondContact N-O 2.83Å; D236-K327 CarbonylContact O-C 3.53Å; D236-K327 WeakPolarHBondContact O-CA 3.36Å; D236-M328 PolarHBondContact O-N 2.96Å
237I97.8Very high92.9Very high0 Ų018 Ų180%011%0.114CC..EExtended strand (participates in β ladder)trans-102.4127.5-175.2-58.6160.4000107.6V213 L214 H215 I235 P239 A288 I313 M328 L330V213-I237 PolarHBondContact O-N 2.76Å; L214-I237 HydrophobicContact CD2-CB 3.79Å; L214-I237 HydrophobicContact CD2-CD1 3.89Å; L214-I237 HydrophobicContact CD2-CG1 4.43Å; L214-I237 HydrophobicContact CD2-CG2 4.07Å; H215-I237 PolarHBondContact N-O 3.06Å; I235-I237 HydrophobicContact CD1-CD1 4.11Å; I237-P239 HydrophobicContact CG2-CG 4.31Å; I237-P239 VanDerWaalsContact O-CD 3.24Å; I237-P239 WeakPolarHBondContact O-CD 3.37Å; I237-A288 HydrophobicContact CG1-CB 4.14Å; I237-A288 HydrophobicContact CG2-CB 3.75Å; I237-I313 HydrophobicContact CD1-CB 4.21Å; I237-I313 HydrophobicContact CD1-CG2 4.09Å; I237-I313 HydrophobicContact CG2-CG2 4.04Å; I237-M328 CarbonylContact C-O 3.58Å; I237-M328 WeakPolarHBondContact CA-O 2.94Å; I237-M328 HydrophobicContact CG1-CB 4.16Å; I237-L330 HydrophobicContact CG2-CD2 3.46Å; I237-L330 VanDerWaalsContact CG2-CD2 3.46Å
238Y97.6Very high92.3Very high9 Ų918.3 Ų18.34%0.03512%0.115CC..EExtended strand (participates in β ladder)trans-114.980.7-179.8-62.8-98.1000109.5H215 T218 Q229 D236 N240 G241 K327 M328 Y329H215-Y238 HydrophobicContact CB-CD1 3.49Å; H215-Y238 VanDerWaalsContact CB-CD1 3.49Å; H215-Y238 HydrophobicContact CB-CE1 3.63Å; H215-Y238 HydrophobicContact CB-CG 4.16Å; H215-Y238 AromaticContact CD2-CE1 3.83Å; H215-Y238 AromaticContact CD2-CZ 3.72Å; H215-Y238 AromaticContact CG-CD1 3.92Å; H215-Y238 AromaticContact CG-CE1 3.56Å; H215-Y238 AromaticContact CG-CZ 3.92Å; H215-Y238 AromaticContact ND1-CE1 3.98Å; H215-Y238 AromaticContact NE2-CZ 3.96Å; T218-Y238 HydrophobicContact CG2-CD1 4.3Å; T218-Y238 HydrophobicContact CG2-CE1 4.24Å; Q229-Y238 PolarHBondContact O-OH 3.47Å; D236-Y238 HydrophobicContact CB-CE2 3.67Å; D236-Y238 WeakPolarHBondContact O-CD2 3.11Å; Y238-N240 PolarHBondContact O-N 2.96Å; Y238-G241 PolarHBondContact O-N 2.76Å; Y238-G241 VanDerWaalsContact O-N 3.14Å; Y238-K327 HydrophobicContact CD2-CB 4.49Å; Y238-K327 HydrophobicContact CE2-CB 4.13Å; Y238-K327 HydrophobicContact CE2-CD 4.14Å; Y238-K327 HydrophobicContact CE2-CG 3.92Å; Y238-M328 PolarHBondContact N-O 3.32Å; Y238-Y329 HydrophobicContact CD2-CE1 4.19Å; Y238-Y329 HydrophobicContact CG-CE1 4.05Å
239P96.8Very high90.7Very high0 Ų021.3 Ų21.30%014%0.14CC..EExtended strand (participates in β ladder)trans-54130.6174.4-21.632.8000111H215 T216 I237 G241 G242 Q245 L274 L330 T332H215-P239 VanDerWaalsContact O-CD 3.23Å; H215-P239 WeakPolarHBondContact O-CD 3.21Å; T216-P239 HydrophobicContact CG2-CB 4.39Å; T216-P239 HydrophobicContact CG2-CG 3.92Å; I237-P239 HydrophobicContact CG2-CG 4.31Å; I237-P239 VanDerWaalsContact O-CD 3.24Å; I237-P239 WeakPolarHBondContact O-CD 3.37Å; P239-G241 PolarHBondContact O-N 2.98Å; P239-G242 PolarHBondContact O-N 3.26Å; P239-Q245 PolarHBondContact O-NE2 3.46Å; P239-L274 HydrophobicContact CB-CD1 3.77Å; P239-L274 HydrophobicContact CG-CD1 3.49Å; P239-L274 VanDerWaalsContact CG-CD1 3.49Å; P239-L330 HydrophobicContact CB-CD2 3.97Å; P239-L330 HydrophobicContact CG-CD2 3.94Å; P239-T332 HydrophobicContact CB-CG2 4.23Å
240N94.6Very high88.7Confident4 Ų424.3 Ų24.32%0.02116%0.157CC..THydrogen-bonded Turntrans63.60.9-178.9-55.6-68.1000116.6Y238 Q245 P246 L330 K331 T332Y238-N240 PolarHBondContact O-N 2.96Å; N240-Q245 PolarHBondContact ND2-OE1 3.01Å; N240-P246 VanDerWaalsContact CG-CD 3.42Å; N240-P246 WeakPolarHBondContact ND2-CD 3.31Å; N240-L330 WeakPolarHBondContact CA-O 3.37Å; N240-L330 PolarHBondContact N-O 2.72Å; N240-K331 HydrophobicContact CB-CD 4.44Å; N240-K331 PolarHBondContact O-NZ 3.2Å; N240-K331 VanDerWaalsContact O-NZ 3.15Å; N240-K331 WeakPolarHBondContact OD1-CA 3.28Å; N240-K331 VanDerWaalsContact OD1-CD 3.31Å; N240-K331 WeakPolarHBondContact OD1-CD 3.47Å; N240-T332 PolarHBondContact ND2-OG1 3.16Å; N240-T332 PolarHBondContact OD1-N 3.01Å
241G92Very high86.4Confident11 Ų1122.6 Ų22.611%0.11315%0.152CC..THydrogen-bonded Turntrans119.4-12.5-170.600000112.7Y238 P239Y238-G241 PolarHBondContact O-N 2.76Å; Y238-G241 VanDerWaalsContact O-N 3.14Å; P239-G241 PolarHBondContact O-N 2.98Å
242G89.2Confident83.9Confident0 Ų027.4 Ų27.40%017%0.172CC..SBendtrans84.8-7-171.400000113.5H215 T216 Y217 T218 P239H215-G242 VanDerWaalsContact O-CA 3.32Å; H215-G242 WeakPolarHBondContact O-CA 3.29Å; T216-G242 CarbonylContact C-O 3.52Å; T216-G242 VanDerWaalsContact C-O 3.25Å; Y217-G242 CarbonylContact C-O 3.6Å; Y217-G242 WeakPolarHBondContact CA-O 3.36Å; Y217-G242 PolarHBondContact N-O 2.83Å; T218-G242 PolarHBondContact N-O 3.14Å; T218-G242 PolarHBondContact OG1-O 2.82Å; T218-G242 VanDerWaalsContact OG1-O 3.11Å; P239-G242 PolarHBondContact O-N 3.26Å
243D82.8Confident81.2Confident54 Ų5435.3 Ų35.329%0.28921%0.211SC..SBendtrans-87.8-77.2-171.450.86.4000113.3R219R219-D243 HydrophobicContact CB-CB 4.38Å
244V82.9Confident78.7Confident48 Ų4839.8 Ų39.829%0.29123%0.234SC..  trans-121.6124.9-173.9179.20000109
245Q90.4Very high76.2Confident0 Ų040.4 Ų40.40%024%0.241CC..  trans-88.4132.2-178.4-56.3-55.5-43.600110.8T216 P239 N240 G247 C248 E267 R270T216-Q245 WeakPolarHBondContact O-CG 3.17Å; T216-Q245 PolarHBondContact O-NE2 3.38Å; P239-Q245 PolarHBondContact O-NE2 3.46Å; N240-Q245 PolarHBondContact ND2-OE1 3.01Å; Q245-G247 PolarHBondContact O-N 2.74Å; Q245-C248 WeakPolarHBondContact O-CB 3.45Å; Q245-C248 PolarHBondContact O-N 3.49Å; Q245-C248 VanDerWaalsContact O-N 3.1Å; Q245-E267 HydrophobicContact CB-CG 4.3Å; Q245-E267 HydrophobicContact CG-CB 4.26Å; Q245-E267 HydrophobicContact CG-CG 4.25Å; Q245-R270 HydrophobicContact CB-CB 4.26Å; Q245-R270 HydrophobicContact CB-CG 3.98Å; Q245-R270 HydrophobicContact CG-CB 3.88Å; Q245-R270 HydrophobicContact CG-CG 3.75Å
246P89.3Confident73.8Confident43 Ų4344.9 Ų44.928%0.27928%0.278SS..THydrogen-bonded Turntrans-54.4133177.4-28.236.6000111.8N240 R270 A334N240-P246 VanDerWaalsContact CG-CD 3.42Å; N240-P246 WeakPolarHBondContact ND2-CD 3.31Å; P246-R270 PolarHBondContact O-NH2 2.86Å; P246-A334 HydrophobicContact CB-CB 4.05Å; P246-A334 VanDerWaalsContact O-CA 3.32Å; P246-A334 WeakPolarHBondContact O-CA 3.1Å
247G83.8Confident71.3Confident56 Ų5648.7 Ų48.758%0.57731%0.31SS*.THydrogen-bonded Turntrans89.4-8.4-177.500000115.6Q245Q245-G247 PolarHBondContact O-N 2.74Å
248C78.8Confident68.8Low6 Ų651.7 Ų51.74%0.04134%0.341CS..THydrogen-bonded Turntrans-91.8-16.3174.5-62.80000113.7Q245 L250 G251 C266 E267Q245-C248 WeakPolarHBondContact O-CB 3.45Å; Q245-C248 PolarHBondContact O-N 3.49Å; Q245-C248 VanDerWaalsContact O-N 3.1Å; C248-L250 PolarHBondContact O-N 2.89Å; C248-L250 VanDerWaalsContact O-N 3.08Å; C248-G251 PolarHBondContact O-N 2.82Å; C248-C266 WeakPolarHBondContact CA-SG 3.34Å; C248-C266 HydrophobicContact CB-CB 3.68Å; C248-C266 WeakPolarHBondContact CB-SG 3.43Å; C248-C266 WeakPolarHBondContact SG-CB 3.43Å; C248-C266 CovalentContact SG-SG 2.05Å; C248-C266 PolarHBondContact SG-SG 3.33Å; C248-E267 HydrophobicContact CB-CG 3.94Å; C248-E267 WeakPolarHBondContact CB-OE1 3.49Å
249A61.6Low66.5Low62 Ų6255.5 Ų55.551%0.51236%0.362SS..THydrogen-bonded Turntrans-64.8-13.7-175.300000116.2G251 E252A249-G251 PolarHBondContact O-N 2.84Å; A249-E252 PolarHBondContact O-N 3.21Å
250L52.4Low64.1Low131 Ų13159.2 Ų59.269%0.68638%0.378SS*.THydrogen-bonded Turntrans-65-15.8170.8-157.273.7000111.7C248 M253 L254C248-L250 PolarHBondContact O-N 2.89Å; C248-L250 VanDerWaalsContact O-N 3.08Å; L250-M253 PolarHBondContact O-N 3.17Å; L250-L254 HydrophobicContact CD2-CD1 4.4Å; L250-L254 HydrophobicContact CG-CD1 4.43Å; L250-L254 PolarHBondContact O-N 2.82Å
251G45.5Very low62Low8 Ų863.4 Ų63.48%0.08240%0.399CS..Hα-helixtrans-65.8-26.8172.800000114.7C248 A249 M253 L254 A255 V263C248-G251 PolarHBondContact O-N 2.82Å; A249-G251 PolarHBondContact O-N 2.84Å; G251-M253 VanDerWaalsContact C-N 3.31Å; G251-M253 PolarHBondContact O-N 2.83Å; G251-L254 PolarHBondContact O-N 3.39Å; G251-A255 WeakPolarHBondContact O-CA 3.24Å; G251-A255 WeakPolarHBondContact O-CB 3.48Å; G251-A255 PolarHBondContact O-N 2.82Å; G251-V263 WeakPolarHBondContact O-CG2 3.44Å
252E43.9Very low60Low127 Ų12769.2 Ų69.259%0.59342%0.423SS*.Hα-helixtrans-68.7-30177.2-71-168.2169.800112R219 A249R219-E252 IonicContact CZ-OE1 2.87Å; R219-E252 IonicContact NH1-OE1 2.63Å; R219-E252 PolarHBondContact NH1-OE1 3.33Å; R219-E252 IonicContact NH2-OE1 3.61Å; A249-E252 PolarHBondContact O-N 3.21Å
253M40.3Very low58.3Low166 Ų16670.3 Ų70.382%0.81843%0.429SS*.Hα-helixtrans-81.6-32.2172.2-100.9-145.6172.200113.5L250 G251L250-M253 PolarHBondContact O-N 3.17Å; G251-M253 VanDerWaalsContact C-N 3.31Å; G251-M253 PolarHBondContact O-N 2.83Å
254L43.7Very low57.1Low95 Ų9569.2 Ų69.250%0.49742%0.423SS..Hα-helixtrans-82.6-23.6177.4-79.7160.2000113.3L250 G251 A256 A257L250-L254 HydrophobicContact CD2-CD1 4.4Å; L250-L254 HydrophobicContact CG-CD1 4.43Å; L250-L254 PolarHBondContact O-N 2.82Å; G251-L254 PolarHBondContact O-N 3.39Å; L254-A256 PolarHBondContact O-N 2.8Å; L254-A257 WeakPolarHBondContact O-CA 3.49Å; L254-A257 WeakPolarHBondContact O-CB 3.35Å; L254-A257 PolarHBondContact O-N 3.02Å
255A45.3Very low56.7Low28 Ų2870.1 Ų70.123%0.23142%0.423CS..Hα-helixtrans-61.2-33.9170.900000111.3G251 A257 G258 F260 V263G251-A255 WeakPolarHBondContact O-CA 3.24Å; G251-A255 WeakPolarHBondContact O-CB 3.48Å; G251-A255 PolarHBondContact O-N 2.82Å; A255-A257 PolarHBondContact O-N 3.04Å; A255-G258 PolarHBondContact O-N 2.78Å; A255-F260 HydrophobicContact CB-CD2 4.27Å; A255-V263 HydrophobicContact CB-CG2 4.33Å
256A44.4Very low56.3Low94 Ų9472.3 Ų72.378%0.77744%0.438SS*.THydrogen-bonded Turntrans-64.7-18.2171.200000113.3L254L254-A256 PolarHBondContact O-N 2.8Å
257A45.1Very low56.3Low80 Ų8070.9 Ų70.966%0.66143%0.427SS*.THydrogen-bonded Turntrans-94.65.5177.300000113.9L254 A255L254-A257 WeakPolarHBondContact O-CA 3.49Å; L254-A257 WeakPolarHBondContact O-CB 3.35Å; L254-A257 PolarHBondContact O-N 3.02Å; A255-A257 PolarHBondContact O-N 3.04Å
258G43.9Very low56.6Low63 Ų6368.9 Ų68.965%0.64940%0.403SS*.THydrogen-bonded Turntrans97.15.2169.700000116.9A255A255-G258 PolarHBondContact O-N 2.78Å
259N50.5Low57.2Low89 Ų8970 Ų7048%0.47641%0.407SS..  trans-101.545.6177.5-86.28000113.4M261 E262 V263N259-M261 PolarHBondContact O-N 3.12Å; N259-M261 VanDerWaalsContact O-N 3.17Å; N259-E262 HydrophobicContact CB-CB 4.35Å; N259-E262 PolarHBondContact ND2-OE2 3.02Å; N259-E262 PolarHBondContact O-N 2.81Å; N259-E262 VanDerWaalsContact O-N 3.09Å; N259-V263 PolarHBondContact O-N 3Å
260F46.6Very low58.8Low79 Ų7967.7 Ų67.735%0.34639%0.386SS..Hα-helixtrans-55.3-35.7-177-169.9-103.1000114L8 A255 E262 V263 M264L8-F260 HydrophobicContact CD1-CD1 4.42Å; A255-F260 HydrophobicContact CB-CD2 4.27Å; F260-E262 PolarHBondContact O-N 3.48Å; F260-V263 PolarHBondContact O-N 3.23Å; F260-M264 HydrophobicContact CD1-CG 4.14Å; F260-M264 HydrophobicContact CE1-CE 3.79Å; F260-M264 HydrophobicContact CE1-CG 3.88Å; F260-M264 HydrophobicContact CE1-SD 4.03Å; F260-M264 HydrophobicContact CZ-CE 3.86Å; F260-M264 HydrophobicContact CZ-CG 4.27Å; F260-M264 HydrophobicContact CZ-SD 3.9Å; F260-M264 WeakPolarHBondContact O-CG 3.45Å; F260-M264 PolarHBondContact O-N 3.2Å
261M50.3Low60.9Low91 Ų9161.5 Ų61.545%0.44835%0.353SS..Hα-helixtrans-69.8-25.7179.1-86.1-106.452.200114.7W87 N259 K265W87-M261 HydrophobicContact CZ3-CE 4.4Å; N259-M261 PolarHBondContact O-N 3.12Å; N259-M261 VanDerWaalsContact O-N 3.17Å; M261-K265 WeakPolarHBondContact O-CG 3.24Å
262E50.4Low63.3Low133 Ų13361.1 Ų61.162%0.62135%0.349SS*.Hα-helixtrans-81.5-28.6177.7-163.7175.4-174.100111N259 F260N259-E262 HydrophobicContact CB-CB 4.35Å; N259-E262 PolarHBondContact ND2-OE2 3.02Å; N259-E262 PolarHBondContact O-N 2.81Å; N259-E262 VanDerWaalsContact O-N 3.09Å; F260-E262 PolarHBondContact O-N 3.48Å
263V51.7Low65.8Low23 Ų2357.2 Ų57.214%0.13933%0.331CS..Hα-helixtrans-72.2-48.6177.3174.80000111.4G251 A255 N259 F260 K265 C266 E267G251-V263 WeakPolarHBondContact O-CG2 3.44Å; A255-V263 HydrophobicContact CB-CG2 4.33Å; N259-V263 PolarHBondContact O-N 3Å; F260-V263 PolarHBondContact O-N 3.23Å; V263-K265 PolarHBondContact O-N 2.95Å; V263-C266 PolarHBondContact O-N 3.42Å; V263-C266 VanDerWaalsContact O-N 3.13Å; V263-E267 VanDerWaalsContact O-OE2 3.04Å
264M59Low68.5Low32 Ų3249.3 Ų49.316%0.15829%0.292CS..Hα-helixtrans-57.9-22.5178.4-65.3-66.4-109.200113.5Y217 I226 F260Y217-M264 HydrophobicContact CE1-CB 4.32Å; Y217-M264 WeakPolarHBondContact CE1-O 3.36Å; Y217-M264 HydrophobicContact CE1-SD 3.89Å; Y217-M264 PolarHBondContact OH-SD 3.04Å; I226-M264 HydrophobicContact CD1-CB 3.68Å; I226-M264 HydrophobicContact CD1-CE 3.21Å; I226-M264 HydrophobicContact CD1-CG 3.95Å; I226-M264 HydrophobicContact CD1-SD 3.59Å; I226-M264 VanDerWaalsContact CD1-SD 3.59Å; I226-M264 HydrophobicContact CG1-CE 3.93Å; F260-M264 HydrophobicContact CD1-CG 4.14Å; F260-M264 HydrophobicContact CE1-CE 3.79Å; F260-M264 HydrophobicContact CE1-CG 3.88Å; F260-M264 HydrophobicContact CE1-SD 4.03Å; F260-M264 HydrophobicContact CZ-CE 3.86Å; F260-M264 HydrophobicContact CZ-CG 4.27Å; F260-M264 HydrophobicContact CZ-SD 3.9Å; F260-M264 WeakPolarHBondContact O-CG 3.45Å; F260-M264 PolarHBondContact O-N 3.2Å
265K73.8Confident71Confident66 Ų6644.8 Ų44.829%0.28727%0.268SS..Hα-helixtrans-78.9-29.2-179.7-72.8-180-175.6-159.70113.6E94 M261 V263 H268 E269E94-K265 WeakPolarHBondContact OE1-CE 3.22Å; E94-K265 IonicContact OE1-NZ 3.53Å; E94-K265 PolarHBondContact OE1-NZ 3Å; M261-K265 WeakPolarHBondContact O-CG 3.24Å; V263-K265 PolarHBondContact O-N 2.95Å; K265-H268 PolarHBondContact O-N 3.09Å; K265-E269 HydrophobicContact CB-CG 4.45Å; K265-E269 VanDerWaalsContact O-CB 3.22Å; K265-E269 WeakPolarHBondContact O-CB 3.41Å; K265-E269 VanDerWaalsContact O-CG 3.29Å; K265-E269 WeakPolarHBondContact O-CG 3.18Å; K265-E269 PolarHBondContact O-N 2.78Å
266C82.9Confident73.5Confident46 Ų4644.6 Ų44.631%0.31126%0.264SS..Hα-helixtrans-64.3-48.9-172.5-176.10000112.2C248 V263 R270C248-C266 WeakPolarHBondContact CA-SG 3.34Å; C248-C266 HydrophobicContact CB-CB 3.68Å; C248-C266 WeakPolarHBondContact CB-SG 3.43Å; C248-C266 WeakPolarHBondContact SG-CB 3.43Å; C248-C266 CovalentContact SG-SG 2.05Å; C248-C266 PolarHBondContact SG-SG 3.33Å; V263-C266 PolarHBondContact O-N 3.42Å; V263-C266 VanDerWaalsContact O-N 3.13Å; C266-R270 PolarHBondContact O-N 3.49Å; C266-R270 VanDerWaalsContact O-N 3.16Å
267E87.8Confident75.9Confident13 Ų1340.4 Ų40.46%0.06123%0.229CC..Hα-helixtrans-66.6-38.6176.9-69.984.3172.200111.4T216 Y217 Q245 C248 V263 R270T216-E267 VanDerWaalsContact CB-O 3.23Å; T216-E267 WeakPolarHBondContact CB-O 3.22Å; T216-E267 PolarHBondContact OG1-O 3.36Å; Y217-E267 HydrophobicContact CD1-CB 3.84Å; Y217-E267 HydrophobicContact CD2-CB 3.79Å; Y217-E267 HydrophobicContact CD2-CG 4.25Å; Y217-E267 HydrophobicContact CE1-CB 4.33Å; Y217-E267 HydrophobicContact CE2-CB 4.34Å; Y217-E267 HydrophobicContact CE2-CG 4.48Å; Y217-E267 HydrophobicContact CG-CB 3.53Å; Y217-E267 HydrophobicContact CG-CG 4.46Å; Q245-E267 HydrophobicContact CB-CG 4.3Å; Q245-E267 HydrophobicContact CG-CB 4.26Å; Q245-E267 HydrophobicContact CG-CG 4.25Å; C248-E267 HydrophobicContact CB-CG 3.94Å; C248-E267 WeakPolarHBondContact CB-OE1 3.49Å; V263-E267 VanDerWaalsContact O-OE2 3.04Å; E267-R270 VanDerWaalsContact O-CB 3.29Å; E267-R270 WeakPolarHBondContact O-CB 3.43Å; E267-R270 PolarHBondContact O-N 3.32Å
268H90.6Very high78.3Confident14 Ų1437.2 Ų37.27%0.06520%0.202CC..Hα-helixtrans-67.5-51.1179.9-160.346.1000111.9Y163 S164 D188 T216 Y217 K265 R270 A271Y163-H268 AromaticContact CE2-CD2 3.86Å; Y163-H268 AromaticContact CZ-CD2 3.52Å; Y163-H268 AromaticContact CZ-NE2 3.97Å; Y163-H268 PolarHBondContact OH-CD2 3.44Å; S164-H268 WeakPolarHBondContact CB-NE2 3.45Å; S164-H268 PolarHBondContact OG-NE2 3.16Å; D188-H268 PolarHBondContact O-CE1 2.88Å; D188-H268 WeakPolarHBondContact OD2-CA 3.44Å; D188-H268 IonicContact OD2-CE1 2.84Å; D188-H268 IonicContact OD2-CG 2.87Å; D188-H268 IonicContact OD2-ND1 3.26Å; D188-H268 PolarHBondContact OD2-ND1 2.87Å; T216-H268 PolarHBondContact OG1-O 3.17Å; Y217-H268 HydrophobicContact CD1-CB 4.28Å; K265-H268 PolarHBondContact O-N 3.09Å; H268-R270 PolarHBondContact O-N 2.83Å; H268-A271 PolarHBondContact O-N 2.91Å
269E92.1Very high80.7Confident29 Ų2934.4 Ų34.414%0.13617%0.172CC..Hα-helixtrans-67.4-15.7178.1-68.9-177.1-154.700112.9W96 Y163 K265 A271 V272 H273W96-E269 VanDerWaalsContact CD1-CD 3.46Å; Y163-E269 VanDerWaalsContact OH-CG 3.28Å; Y163-E269 WeakPolarHBondContact OH-CG 3.26Å; K265-E269 HydrophobicContact CB-CG 4.45Å; K265-E269 VanDerWaalsContact O-CB 3.22Å; K265-E269 WeakPolarHBondContact O-CB 3.41Å; K265-E269 VanDerWaalsContact O-CG 3.29Å; K265-E269 WeakPolarHBondContact O-CG 3.18Å; K265-E269 PolarHBondContact O-N 2.78Å; E269-A271 PolarHBondContact O-N 3.43Å; E269-V272 WeakPolarHBondContact O-CB 3.36Å; E269-V272 PolarHBondContact O-N 3.26Å; E269-H273 PolarHBondContact O-N 2.95Å; E269-H273 VanDerWaalsContact O-N 3.14Å
270R94.4Very high82.6Confident15 Ų1534 Ų346%0.05717%0.168CC..Hα-helixtrans-56.7-34.8176.8-178.857.360.9130.66.2112T216 Q245 P246 C266 E267 H268 V272 H273 L274 R333 A334T216-R270 HydrophobicContact CG2-CB 4.23Å; T216-R270 HydrophobicContact CG2-CG 4.14Å; Q245-R270 HydrophobicContact CB-CB 4.26Å; Q245-R270 HydrophobicContact CB-CG 3.98Å; Q245-R270 HydrophobicContact CG-CB 3.88Å; Q245-R270 HydrophobicContact CG-CG 3.75Å; P246-R270 PolarHBondContact O-NH2 2.86Å; C266-R270 PolarHBondContact O-N 3.49Å; C266-R270 VanDerWaalsContact O-N 3.16Å; E267-R270 VanDerWaalsContact O-CB 3.29Å; E267-R270 WeakPolarHBondContact O-CB 3.43Å; E267-R270 PolarHBondContact O-N 3.32Å; H268-R270 PolarHBondContact O-N 2.83Å; R270-V272 VanDerWaalsContact C-N 3.3Å; R270-V272 PolarHBondContact O-N 3.48Å; R270-H273 PolarHBondContact O-N 2.99Å; R270-L274 HydrophobicContact CG-CD1 3.9Å; R270-L274 HydrophobicContact CG-CG 4.07Å; R270-L274 WeakPolarHBondContact O-CB 3.35Å; R270-L274 WeakPolarHBondContact O-CG 3.47Å; R270-L274 PolarHBondContact O-N 3.09Å; R270-R333 PolarHBondContact NH1-O 3.37Å; R270-A334 PolarHBondContact NH1-O 2.69Å; R270-A334 VanDerWaalsContact NH1-O 3.09Å; R270-A334 PolarHBondContact NH2-O 2.79Å; R270-A334 VanDerWaalsContact NH2-O 3.09Å
271A96.7Very high84.5Confident0 Ų032.5 Ų32.50%016%0.164CC..Hα-helixtrans-58.4-43.2175.900000111.7L187 D188 L214 T216 H268 E269 L274 F275L187-A271 HydrophobicContact CB-CB 3.99Å; D188-A271 HydrophobicContact CB-CB 3.78Å; L214-A271 HydrophobicContact CB-CB 3.98Å; L214-A271 WeakPolarHBondContact CD1-O 3.46Å; T216-A271 HydrophobicContact CG2-CB 4.05Å; T216-A271 WeakPolarHBondContact OG1-CB 3.38Å; T216-A271 PolarHBondContact OG1-N 3.02Å; H268-A271 PolarHBondContact O-N 2.91Å; E269-A271 PolarHBondContact O-N 3.43Å; A271-L274 PolarHBondContact O-N 3.33Å; A271-F275 PolarHBondContact O-N 2.05Å
272V96.9Very high85.7Confident0 Ų034.2 Ų34.20%017%0.168CC..Hα-helixtrans-62-47.7175.3-170.60000110.6W96 L100 Y163 L187 E269 R270 L274 F275 V276W96-V272 HydrophobicContact CB-CG1 4.11Å; W96-V272 HydrophobicContact CD2-CG1 4.09Å; W96-V272 HydrophobicContact CD2-CG2 4.07Å; W96-V272 HydrophobicContact CE3-CB 4.35Å; W96-V272 HydrophobicContact CE3-CG1 3.55Å; W96-V272 HydrophobicContact CE3-CG2 3.98Å; W96-V272 HydrophobicContact CG-CG1 4.33Å; W96-V272 HydrophobicContact CG-CG2 4.43Å; W96-V272 HydrophobicContact CZ3-CG1 4.38Å; L100-V272 HydrophobicContact CB-CG1 4.03Å; L100-V272 HydrophobicContact CD2-CG1 4.12Å; L100-V272 HydrophobicContact CG-CG1 4.47Å; Y163-V272 HydrophobicContact CD2-CG2 3.56Å; Y163-V272 HydrophobicContact CE2-CG2 3.89Å; Y163-V272 HydrophobicContact CG-CG2 4.04Å; L187-V272 HydrophobicContact CD1-CG2 4.21Å; E269-V272 WeakPolarHBondContact O-CB 3.36Å; E269-V272 PolarHBondContact O-N 3.26Å; R270-V272 VanDerWaalsContact C-N 3.3Å; R270-V272 PolarHBondContact O-N 3.48Å; V272-L274 PolarHBondContact O-N 3.38Å; V272-F275 PolarHBondContact O-N 3.13Å; V272-F275 VanDerWaalsContact O-N 3.17Å; V272-V276 HydrophobicContact CG1-CG2 4.47Å; V272-V276 WeakPolarHBondContact O-CG2 3.23Å; V272-V276 PolarHBondContact O-N 2.87Å
273H95.6Very high86.7Confident46 Ų4636.5 Ų36.521%0.21318%0.179CC..Hα-helixtrans-64.4-38.1-179.4-67.9-34.9000113.1E269 R270 F275 V276 D277 F338E269-H273 PolarHBondContact O-N 2.95Å; E269-H273 VanDerWaalsContact O-N 3.14Å; R270-H273 PolarHBondContact O-N 2.99Å; H273-F275 VanDerWaalsContact C-N 3.33Å; H273-V276 PolarHBondContact O-N 2.91Å; H273-D277 WeakPolarHBondContact O-CB 3.23Å; H273-D277 PolarHBondContact O-N 3.35Å; H273-F338 HydrophobicContact CB-CE2 3.81Å; H273-F338 HydrophobicContact CB-CZ 3.99Å; H273-F338 WeakPolarHBondContact O-CE2 3.39Å
274L96.6Very high87.7Confident0 Ų039.4 Ų39.40%019%0.191CC..Hα-helixtrans-64.9-38.2173.4-71.9171.3000111.7L214 T216 P239 R270 A271 V272 D277 S278 I313 T332 F338L214-L274 HydrophobicContact CD1-CB 4.17Å; T216-L274 HydrophobicContact CG2-CD1 3.92Å; P239-L274 HydrophobicContact CB-CD1 3.77Å; P239-L274 HydrophobicContact CG-CD1 3.49Å; P239-L274 VanDerWaalsContact CG-CD1 3.49Å; R270-L274 HydrophobicContact CG-CD1 3.9Å; R270-L274 HydrophobicContact CG-CG 4.07Å; R270-L274 WeakPolarHBondContact O-CB 3.35Å; R270-L274 WeakPolarHBondContact O-CG 3.47Å; R270-L274 PolarHBondContact O-N 3.09Å; A271-L274 PolarHBondContact O-N 3.33Å; V272-L274 PolarHBondContact O-N 3.38Å; L274-D277 PolarHBondContact O-N 2.96Å; L274-S278 PolarHBondContact O-N 3.3Å; L274-I313 HydrophobicContact CD2-CD1 4.38Å; L274-T332 HydrophobicContact CD2-CG2 3.95Å; L274-F338 HydrophobicContact CD2-CB 3.67Å; L274-F338 HydrophobicContact CD2-CD2 3.76Å; L274-F338 HydrophobicContact CD2-CG 3.79Å; L274-F338 HydrophobicContact CG-CD2 4.5Å
275F97.4Very high88.7Confident0 Ų041.8 Ų41.80%020%0.203CC..Hα-helixtrans-66.6-45.4175.1-166.6-90.4000111.8L100 I161 T185 L187 L214 A271 V272 H273 D277 S278 L279 Y315L100-F275 HydrophobicContact CD1-CD1 3.68Å; L100-F275 HydrophobicContact CD1-CE1 4.18Å; I161-F275 HydrophobicContact CD1-CE1 3.69Å; I161-F275 HydrophobicContact CD1-CZ 3.85Å; I161-F275 HydrophobicContact CG1-CE1 4.47Å; I161-F275 HydrophobicContact CG1-CZ 4.27Å; T185-F275 HydrophobicContact CG2-CD2 3.9Å; T185-F275 HydrophobicContact CG2-CE2 3.66Å; L187-F275 HydrophobicContact CD1-CB 4.39Å; L187-F275 HydrophobicContact CD2-CB 3.76Å; L187-F275 HydrophobicContact CD2-CD2 3.91Å; L187-F275 HydrophobicContact CD2-CG 4Å; L214-F275 HydrophobicContact CD1-CB 4.44Å; A271-F275 PolarHBondContact O-N 2.05Å; V272-F275 PolarHBondContact O-N 3.13Å; V272-F275 VanDerWaalsContact O-N 3.17Å; H273-F275 VanDerWaalsContact C-N 3.33Å; F275-D277 VanDerWaalsContact C-N 3.32Å; F275-D277 PolarHBondContact O-N 3.03Å; F275-S278 WeakPolarHBondContact O-CB 3.32Å; F275-S278 PolarHBondContact O-N 3.08Å; F275-S278 VanDerWaalsContact O-N 3.12Å; F275-S278 PolarHBondContact O-OG 3.29Å; F275-L279 HydrophobicContact CD1-CD1 3.88Å; F275-L279 HydrophobicContact CD1-CG 4.35Å; F275-L279 HydrophobicContact CE1-CD1 3.84Å; F275-L279 HydrophobicContact CE1-CD2 4.44Å; F275-L279 HydrophobicContact CE1-CG 4.22Å; F275-L279 PolarHBondContact O-N 3.24Å; F275-Y315 HydrophobicContact CE1-CD2 4.35Å; F275-Y315 AromaticContact CZ-CD2 3.87Å; F275-Y315 HydrophobicContact CZ-CD2 3.87Å
276V96.3Very high89.4Confident24 Ų2439.2 Ų39.215%0.14519%0.193CC..Hα-helixtrans-56.7-45.7173.3169.20000111.5L100 A103 V272 H273 S278 L279 M280L100-V276 HydrophobicContact CB-CG2 4.13Å; L100-V276 HydrophobicContact CD1-CG2 3.92Å; A103-V276 HydrophobicContact CB-CB 4.48Å; A103-V276 HydrophobicContact CB-CG1 3.9Å; A103-V276 HydrophobicContact CB-CG2 4.31Å; V272-V276 HydrophobicContact CG1-CG2 4.47Å; V272-V276 WeakPolarHBondContact O-CG2 3.23Å; V272-V276 PolarHBondContact O-N 2.87Å; H273-V276 PolarHBondContact O-N 2.91Å; V276-S278 VanDerWaalsContact C-N 3.27Å; V276-S278 PolarHBondContact O-N 3.47Å; V276-L279 WeakPolarHBondContact O-CB 3.48Å; V276-L279 PolarHBondContact O-N 3.01Å; V276-L279 VanDerWaalsContact O-N 3.1Å; V276-M280 HydrophobicContact CG1-CG 4.44Å; V276-M280 WeakPolarHBondContact O-CG 3.13Å; V276-M280 PolarHBondContact O-N 2.89Å; V276-M280 VanDerWaalsContact O-N 3.16Å
277D95Very high89.8Confident6 Ų640.5 Ų40.53%0.03219%0.192CC..Hα-helixtrans-57.9-41.2176.7-163.472.2000111.5H273 L274 F275 L279 M280 N281 T336 P337 F338H273-D277 WeakPolarHBondContact O-CB 3.23Å; H273-D277 PolarHBondContact O-N 3.35Å; L274-D277 PolarHBondContact O-N 2.96Å; F275-D277 VanDerWaalsContact C-N 3.32Å; F275-D277 PolarHBondContact O-N 3.03Å; D277-L279 VanDerWaalsContact C-N 3.28Å; D277-L279 PolarHBondContact O-N 3.37Å; D277-M280 PolarHBondContact O-N 2.84Å; D277-N281 WeakPolarHBondContact O-CB 3.33Å; D277-N281 PolarHBondContact O-N 2.84Å; D277-N281 PolarHBondContact OD1-ND2 3.33Å; D277-T336 PolarHBondContact OD1-OG1 3.47Å; D277-P337 WeakPolarHBondContact OD1-CA 3.35Å; D277-F338 HydrophobicContact CB-CD2 3.58Å; D277-F338 HydrophobicContact CB-CE2 4.1Å; D277-F338 PolarHBondContact OD1-N 2.93Å; D277-F338 PolarHBondContact OD2-N 2.81Å; D277-F338 VanDerWaalsContact OD2-N 3.14Å
278S95.1Very high90.2Very high13 Ų1339.9 Ų39.99%0.09119%0.189CC..Hα-helixtrans-66.9-25178.181.30000114.4L274 F275 V276 I313 G314 Y315 N316L274-S278 PolarHBondContact O-N 3.3Å; F275-S278 WeakPolarHBondContact O-CB 3.32Å; F275-S278 PolarHBondContact O-N 3.08Å; F275-S278 VanDerWaalsContact O-N 3.12Å; F275-S278 PolarHBondContact O-OG 3.29Å; V276-S278 VanDerWaalsContact C-N 3.27Å; V276-S278 PolarHBondContact O-N 3.47Å; S278-I313 WeakPolarHBondContact CB-O 3.37Å; S278-G314 WeakPolarHBondContact OG-CA 3.48Å; S278-Y315 PolarHBondContact OG-N 3.18Å; S278-N316 PolarHBondContact O-ND2 3.09Å
279L94.2Very high90.5Very high3 Ų339.2 Ų39.22%0.01619%0.186CC..Hα-helixtrans-75.9-45175.5-70.3165.2000110.7L100 A103 V104 R107 F275 V276 D277 Y315L100-L279 HydrophobicContact CD1-CD1 4.37Å; A103-L279 HydrophobicContact CB-CB 4.28Å; A103-L279 HydrophobicContact CB-CD1 3.81Å; V104-L279 HydrophobicContact CG2-CD1 3.65Å; R107-L279 HydrophobicContact CB-CB 4.35Å; R107-L279 HydrophobicContact CB-CD2 3.84Å; R107-L279 HydrophobicContact CG-CD2 3.69Å; R107-L279 PolarHBondContact NH1-O 3.45Å; R107-L279 VanDerWaalsContact NH1-O 3.09Å; F275-L279 HydrophobicContact CD1-CD1 3.88Å; F275-L279 HydrophobicContact CD1-CG 4.35Å; F275-L279 HydrophobicContact CE1-CD1 3.84Å; F275-L279 HydrophobicContact CE1-CD2 4.44Å; F275-L279 HydrophobicContact CE1-CG 4.22Å; F275-L279 PolarHBondContact O-N 3.24Å; V276-L279 WeakPolarHBondContact O-CB 3.48Å; V276-L279 PolarHBondContact O-N 3.01Å; V276-L279 VanDerWaalsContact O-N 3.1Å; D277-L279 VanDerWaalsContact C-N 3.28Å; D277-L279 PolarHBondContact O-N 3.37Å; L279-Y315 VanDerWaalsContact CD2-CB 3.49Å; L279-Y315 HydrophobicContact CD2-CD1 3.87Å; L279-Y315 HydrophobicContact CD2-CD2 3.49Å; L279-Y315 VanDerWaalsContact CD2-CD2 3.49Å; L279-Y315 HydrophobicContact CD2-CE2 4.19Å; L279-Y315 HydrophobicContact CD2-CG 3.31Å; L279-Y315 HydrophobicContact CG-CG 4.37Å
280M91.3Very high90.7Very high81 Ų8139.6 Ų39.640%0.39919%0.188SC..Hα-helixtrans-90.1-37.3-168.5-59.2-52.1-68.400113.6A103 Q106 V276 D277 K282A103-M280 HydrophobicContact CB-CG 3.99Å; A103-M280 HydrophobicContact CB-SD 3.84Å; Q106-M280 HydrophobicContact CB-SD 4.46Å; V276-M280 HydrophobicContact CG1-CG 4.44Å; V276-M280 WeakPolarHBondContact O-CG 3.13Å; V276-M280 PolarHBondContact O-N 2.89Å; V276-M280 VanDerWaalsContact O-N 3.16Å; D277-M280 PolarHBondContact O-N 2.84Å; M280-K282 PolarHBondContact O-N 2.92Å
281N85.8Confident90.7Very high48 Ų4839.4 Ų39.426%0.25719%0.189SC..  trans-99.571.9-170.7-67.8-55000112.6D277 E283 H284D277-N281 WeakPolarHBondContact O-CB 3.33Å; D277-N281 PolarHBondContact O-N 2.84Å; D277-N281 PolarHBondContact OD1-ND2 3.33Å; N281-E283 VanDerWaalsContact C-N 3.28Å; N281-E283 PolarHBondContact O-N 3.4Å; N281-H284 PolarHBondContact O-N 2.86Å
282K75.8Confident90.4Very high126 Ų12644.5 Ų44.555%0.54822%0.22SC..SBendtrans-62.5-30.7-179.8-69.5177.3179.3171.40113.9R107 M280 M285R107-K282 VanDerWaalsContact CZ-CE 3.42Å; M280-K282 PolarHBondContact O-N 2.92Å; K282-M285 VanDerWaalsContact O-CE 3.29Å; K282-M285 WeakPolarHBondContact O-CE 3.45Å
283E71.9Confident90.1Very high182 Ų18245.2 Ų45.285%0.8523%0.227SC*.SBendtrans-84.3-21.4-176-61.9-175.2170.900112.9N281N281-E283 VanDerWaalsContact C-N 3.28Å; N281-E283 PolarHBondContact O-N 3.4Å
284H73.1Confident89.9Confident83 Ų8344.9 Ų44.938%0.38423%0.229SC..SBendtrans-116.755-178.3-72.482.2000111.1N281 S286 P337N281-H284 PolarHBondContact O-N 2.86Å; H284-S286 PolarHBondContact O-N 3.08Å; H284-P337 HydrophobicContact CB-CB 4.42Å
285M78.9Confident89.6Confident83 Ų8349.1 Ų49.141%0.40925%0.251SS..  trans-65.3128.7-179.9-75.7-174.6-95.600111.9K282K282-M285 VanDerWaalsContact O-CE 3.29Å; K282-M285 WeakPolarHBondContact O-CE 3.45Å
286S89.4Confident89.4Confident12 Ų1254.6 Ų54.68%0.08427%0.272CS..  trans-86.2133.6173.9-67.30000111.1H284 I313 G339H284-S286 PolarHBondContact O-N 3.08Å; S286-I313 VanDerWaalsContact CB-CD1 3.43Å; S286-I313 PolarHBondContact O-N 3.08Å; S286-G339 WeakPolarHBondContact OG-CA 3.46Å
287Y91.8Very high89.4Confident72 Ų7253.6 Ų53.628%0.28227%0.266SS..EExtended strand (participates in β ladder)trans-106.7132.4175.8-63-82.4000111.1N311 N312 L330 E454Y287-N311 CarbonylContact C-O 3.58Å; Y287-N311 WeakPolarHBondContact CA-O 3.19Å; Y287-N312 VanDerWaalsContact CE1-OD1 3.27Å; Y287-N312 WeakPolarHBondContact CE1-OD1 3.42Å; Y287-L330 WeakPolarHBondContact O-CB 3.46Å; Y287-E454 HydrophobicContact CD2-CG 4.17Å
288A96.2Very high89.2Confident0 Ų056.4 Ų56.40%028%0.278CS..EExtended strand (participates in β ladder)trans-98145.8166.700000110.5I237 C310 N311 I313 M328 L330I237-A288 HydrophobicContact CG1-CB 4.14Å; I237-A288 HydrophobicContact CG2-CB 3.75Å; A288-C310 CarbonylContact O-C 3.58Å; A288-C310 WeakPolarHBondContact O-CA 3.24Å; A288-C310 WeakPolarHBondContact O-CB 3.28Å; A288-N311 PolarHBondContact N-O 3.1Å; A288-N311 PolarHBondContact O-N 2.86Å; A288-I313 HydrophobicContact CB-CG2 3.76Å; A288-M328 HydrophobicContact CB-CB 3.72Å; A288-M328 HydrophobicContact CB-SD 4.28Å; A288-L330 HydrophobicContact CB-CD2 4.12Å
289Y96.3Very high89Confident0 Ų058.4 Ų58.40%029%0.285CS..EExtended strand (participates in β ladder)trans-118.2125.5-175.1-60.9-83.1000111C291 F297 C302 L303 C310 M328 Y329 H342 G453 E454Y289-C291 PolarHBondContact O-N 3.26Å; Y289-F297 HydrophobicContact CD2-CE2 4Å; Y289-C302 WeakPolarHBondContact CB-O 3.48Å; Y289-L303 HydrophobicContact CD1-CB 4.49Å; Y289-L303 HydrophobicContact CD1-CD2 4.39Å; Y289-L303 HydrophobicContact CD2-CD2 3.71Å; Y289-L303 HydrophobicContact CE1-CB 4.38Å; Y289-L303 HydrophobicContact CE1-CD2 4.41Å; Y289-L303 HydrophobicContact CE2-CD2 3.74Å; Y289-L303 HydrophobicContact CG-CD2 4.04Å; Y289-C310 HydrophobicContact CD1-CB 3.73Å; Y289-C310 HydrophobicContact CE1-CB 4.01Å; Y289-M328 CarbonylContact O-C 3.59Å; Y289-M328 VanDerWaalsContact O-CA 3.31Å; Y289-M328 WeakPolarHBondContact O-CA 3.13Å; Y289-Y329 PolarHBondContact N-O 3.2Å; Y289-Y329 PolarHBondContact O-N 3.26Å; Y289-H342 HydrophobicContact CE2-CB 4.28Å; Y289-H342 AromaticContact CE2-CG 3.97Å; Y289-H342 AromaticContact CE2-ND1 3.85Å; Y289-G453 WeakPolarHBondContact OH-CA 3.41Å; Y289-E454 PolarHBondContact OH-N 2.89Å; Y289-E454 PolarHBondContact OH-OE1 2.79Å
290Q95.3Very high89Confident38 Ų3858.2 Ų58.218%0.17828%0.284CS..EExtended strand (participates in β ladder)trans-60.7125.9176.9-168.5-178.63500110.5R309 S326 K327 M328Q290-R309 HydrophobicContact CB-CB 4.34Å; Q290-R309 WeakPolarHBondContact CB-O 3.43Å; Q290-R309 PolarHBondContact N-O 3.03Å; Q290-S326 PolarHBondContact NE2-OG 2.81Å; Q290-K327 WeakPolarHBondContact CA-O 3.44Å; Q290-M328 HydrophobicContact CB-CE 3.94Å; Q290-M328 HydrophobicContact CB-CG 4.34Å
291C94.7Very high89.1Confident11 Ų1157.6 Ų57.67%0.07428%0.281CS..  trans-146.9156.9-179.8-153.40000110.3Y289 G293 F297 C302 K327 Y329Y289-C291 PolarHBondContact O-N 3.26Å; C291-G293 VanDerWaalsContact C-N 3.26Å; C291-G293 PolarHBondContact O-N 2.79Å; C291-G293 PolarHBondContact SG-O 2.81Å; C291-F297 HydrophobicContact CB-CB 4.33Å; C291-F297 PolarHBondContact SG-N 2.87Å; C291-F297 VanDerWaalsContact SG-N 3.43Å; C291-C302 VanDerWaalsContact CA-SG 3.54Å; C291-C302 HydrophobicContact CB-CB 3.48Å; C291-C302 VanDerWaalsContact CB-CB 3.48Å; C291-C302 WeakPolarHBondContact CB-SG 3.12Å; C291-C302 WeakPolarHBondContact SG-CB 3.05Å; C291-C302 CovalentContact SG-SG 2.03Å; C291-C302 PolarHBondContact SG-SG 2.74Å; C291-K327 PolarHBondContact N-O 3.26Å; C291-K327 VanDerWaalsContact N-O 3.08Å; C291-Y329 HydrophobicContact CB-CD2 3.5Å; C291-Y329 VanDerWaalsContact CB-CD2 3.5Å; C291-Y329 HydrophobicContact CB-CE2 3.82Å
292T91.6Very high89.5Confident107 Ų10756 Ų5666%0.65627%0.274SS*.SBendtrans-79.2-11.7178.759.80000113.1R296T292-R296 WeakPolarHBondContact OG1-CD 3.13Å; T292-R296 PolarHBondContact OG1-NH1 3.45Å
293G91Very high90.5Very high14 Ų1450 Ų5014%0.14425%0.248CC..  trans177.6163.7179.900000112.3C291 D295 R296 F297C291-G293 VanDerWaalsContact C-N 3.26Å; C291-G293 PolarHBondContact O-N 2.79Å; C291-G293 PolarHBondContact SG-O 2.81Å; G293-D295 VanDerWaalsContact C-N 3.33Å; G293-D295 PolarHBondContact O-N 3.14Å; G293-R296 PolarHBondContact O-N 3.38Å; G293-F297 PolarHBondContact O-N 2.94Å
294P91.1Very high91.5Very high39 Ų3942.5 Ų42.525%0.25322%0.215SC..Hα-helixtrans-63.4-35.1-175.325.1-33.7000112.6R296 F297 K298 Y329P294-R296 PolarHBondContact O-N 2.7Å; P294-F297 CarbonylContact O-C 3.53Å; P294-F297 WeakPolarHBondContact O-CA 3.28Å; P294-F297 WeakPolarHBondContact O-CB 3.29Å; P294-F297 PolarHBondContact O-N 2.94Å; P294-F297 VanDerWaalsContact O-N 3.1Å; P294-K298 WeakPolarHBondContact O-CG 3.42Å; P294-K298 PolarHBondContact O-N 2.86Å; P294-Y329 HydrophobicContact CB-CD1 4.26Å; P294-Y329 HydrophobicContact CB-CE1 3.89Å; P294-Y329 HydrophobicContact CG-CE1 4.42Å
295D90.5Very high92.5Very high89 Ų8940.3 Ų40.348%0.47621%0.209SC..Hα-helixtrans-66.3-38.1-176.7-57.8-35.2000112.9G293 F297 K298 K299G293-D295 VanDerWaalsContact C-N 3.33Å; G293-D295 PolarHBondContact O-N 3.14Å; D295-F297 VanDerWaalsContact C-N 3.3Å; D295-K298 PolarHBondContact O-N 3.32Å; D295-K299 WeakPolarHBondContact O-CG 3.26Å; D295-K299 PolarHBondContact O-N 2.8Å; D295-K299 VanDerWaalsContact O-N 3.11Å
296R93.3Very high93Very high116 Ų11645.5 Ų45.544%0.43822%0.224SC..Hα-helixtrans-69.7-32.4174.5-67.4-174.376.6-175.57.3111.8T292 G293 P294 K299 I301T292-R296 WeakPolarHBondContact OG1-CD 3.13Å; T292-R296 PolarHBondContact OG1-NH1 3.45Å; G293-R296 PolarHBondContact O-N 3.38Å; P294-R296 PolarHBondContact O-N 2.7Å; R296-K299 PolarHBondContact O-N 2.84Å; R296-I301 HydrophobicContact CB-CD1 4.42Å; R296-I301 WeakPolarHBondContact O-CB 3.32Å; R296-I301 PolarHBondContact O-N 2.9Å; R296-I301 VanDerWaalsContact O-N 3.13Å
297F94.4Very high92.9Very high3 Ų354 Ų541%0.01326%0.259CS..Hα-helixtrans-68.2-46.1173.8176.6-104.1000111.1Y289 C291 G293 P294 D295 K299 G300 C302 L303 Y329 L330 K331 H342 L393Y289-F297 HydrophobicContact CD2-CE2 4Å; C291-F297 HydrophobicContact CB-CB 4.33Å; C291-F297 PolarHBondContact SG-N 2.87Å; C291-F297 VanDerWaalsContact SG-N 3.43Å; G293-F297 PolarHBondContact O-N 2.94Å; P294-F297 CarbonylContact O-C 3.53Å; P294-F297 WeakPolarHBondContact O-CA 3.28Å; P294-F297 WeakPolarHBondContact O-CB 3.29Å; P294-F297 PolarHBondContact O-N 2.94Å; P294-F297 VanDerWaalsContact O-N 3.1Å; D295-F297 VanDerWaalsContact C-N 3.3Å; F297-K299 PolarHBondContact O-N 2.77Å; F297-G300 WeakPolarHBondContact O-CA 3.44Å; F297-G300 PolarHBondContact O-N 2.83Å; F297-C302 HydrophobicContact CD2-CB 4.45Å; F297-L303 HydrophobicContact CE2-CD2 3.98Å; F297-Y329 HydrophobicContact CB-CD2 4.4Å; F297-Y329 HydrophobicContact CB-CG 4.14Å; F297-Y329 HydrophobicContact CD1-CG 4.43Å; F297-Y329 WeakPolarHBondContact CE2-O 3.39Å; F297-Y329 VanDerWaalsContact CG-CB 3.43Å; F297-Y329 HydrophobicContact CG-CG 4.18Å; F297-L330 VanDerWaalsContact CZ-CA 3.41Å; F297-K331 HydrophobicContact CE1-CG 4.2Å; F297-H342 AromaticContact CZ-CD2 3.91Å; F297-L393 HydrophobicContact CD1-CD2 4.1Å; F297-L393 HydrophobicContact CE1-CD2 3.57Å; F297-L393 HydrophobicContact CE2-CD2 4.3Å; F297-L393 HydrophobicContact CZ-CD2 3.65Å
298K91.5Very high92.6Very high64 Ų6454.7 Ų54.728%0.27827%0.268SS..Hα-helixtrans-57-29.3174-70.2172.6-177.1176.10112.5P294 D295 G300 L393P294-K298 WeakPolarHBondContact O-CG 3.42Å; P294-K298 PolarHBondContact O-N 2.86Å; D295-K298 PolarHBondContact O-N 3.32Å; K298-G300 VanDerWaalsContact C-N 3.26Å; K298-G300 PolarHBondContact O-N 3.15Å; K298-L393 WeakPolarHBondContact O-CB 3.48Å; K298-L393 PolarHBondContact O-N 3.22Å
299K91.7Very high92.4Very high55 Ų5560.9 Ų60.924%0.23929%0.292CS..THydrogen-bonded Turntrans-77.9-0.6171.9-73171.7-177.4176.60114.6D295 R296 F297 I301 D382 T391 F392D295-K299 WeakPolarHBondContact O-CG 3.26Å; D295-K299 PolarHBondContact O-N 2.8Å; D295-K299 VanDerWaalsContact O-N 3.11Å; R296-K299 PolarHBondContact O-N 2.84Å; F297-K299 PolarHBondContact O-N 2.77Å; K299-I301 VanDerWaalsContact C-N 3.25Å; K299-I301 HydrophobicContact CB-CD1 3.77Å; K299-I301 HydrophobicContact CB-CG1 3.85Å; K299-I301 HydrophobicContact CD-CD1 4.25Å; K299-I301 PolarHBondContact O-N 3.01Å; K299-D382 WeakPolarHBondContact CE-OD2 3.33Å; K299-D382 IonicContact NZ-OD1 3.54Å; K299-D382 IonicContact NZ-OD2 2.76Å; K299-D382 PolarHBondContact NZ-OD2 2.91Å; K299-T391 HydrophobicContact CB-CG2 4.11Å; K299-T391 CarbonylContact O-C 3.59Å; K299-T391 PolarHBondContact O-OG1 3.45Å; K299-F392 PolarHBondContact O-N 2.83Å
300G92.7Very high92.3Very high0 Ų061.9 Ų61.90%030%0.298CS..THydrogen-bonded Turntrans7211.2-178.300000114.4F297 K298 C302 Q344F297-G300 WeakPolarHBondContact O-CA 3.44Å; F297-G300 PolarHBondContact O-N 2.83Å; K298-G300 VanDerWaalsContact C-N 3.26Å; K298-G300 PolarHBondContact O-N 3.15Å; G300-C302 VanDerWaalsContact C-N 3.28Å; G300-C302 PolarHBondContact O-N 2.99Å; G300-Q344 VanDerWaalsContact O-CB 3.28Å; G300-Q344 WeakPolarHBondContact O-CB 3.41Å; G300-Q344 VanDerWaalsContact O-CG 3.25Å; G300-Q344 WeakPolarHBondContact O-CG 3.1Å; G300-Q344 PolarHBondContact O-NE2 3.37Å
301I93.9Very high92.3Very high67 Ų6760.8 Ų60.834%0.34429%0.294SS..THydrogen-bonded Turntrans-69.6-28.7-170.3-61.7171.4000112R296 K299 T391R296-I301 HydrophobicContact CB-CD1 4.42Å; R296-I301 WeakPolarHBondContact O-CB 3.32Å; R296-I301 PolarHBondContact O-N 2.9Å; R296-I301 VanDerWaalsContact O-N 3.13Å; K299-I301 VanDerWaalsContact C-N 3.25Å; K299-I301 HydrophobicContact CB-CD1 3.77Å; K299-I301 HydrophobicContact CB-CG1 3.85Å; K299-I301 HydrophobicContact CD-CD1 4.25Å; K299-I301 PolarHBondContact O-N 3.01Å; I301-T391 HydrophobicContact CD1-CG2 4.4Å; I301-T391 HydrophobicContact CG1-CG2 4.18Å
302C95.3Very high92.2Very high16 Ų1661.3 Ų61.311%0.10830%0.296CS..THydrogen-bonded Turntrans-98.512.4-164.3-68.10000115.8Y289 C291 F297 G300 S304Y289-C302 WeakPolarHBondContact CB-O 3.48Å; C291-C302 VanDerWaalsContact CA-SG 3.54Å; C291-C302 HydrophobicContact CB-CB 3.48Å; C291-C302 VanDerWaalsContact CB-CB 3.48Å; C291-C302 WeakPolarHBondContact CB-SG 3.12Å; C291-C302 WeakPolarHBondContact SG-CB 3.05Å; C291-C302 CovalentContact SG-SG 2.03Å; C291-C302 PolarHBondContact SG-SG 2.74Å; F297-C302 HydrophobicContact CD2-CB 4.45Å; G300-C302 VanDerWaalsContact C-N 3.28Å; G300-C302 PolarHBondContact O-N 2.99Å; C302-S304 PolarHBondContact O-N 3.11Å
303L95.9Very high92.3Very high0 Ų056.5 Ų56.50%027%0.266CS..  trans-7534.3-173.5-57.6-176.5000116.2Y289 F297 H342 Q344 L393 K451 Q456Y289-L303 HydrophobicContact CD1-CB 4.49Å; Y289-L303 HydrophobicContact CD1-CD2 4.39Å; Y289-L303 HydrophobicContact CD2-CD2 3.71Å; Y289-L303 HydrophobicContact CE1-CB 4.38Å; Y289-L303 HydrophobicContact CE1-CD2 4.41Å; Y289-L303 HydrophobicContact CE2-CD2 3.74Å; Y289-L303 HydrophobicContact CG-CD2 4.04Å; F297-L303 HydrophobicContact CE2-CD2 3.98Å; L303-H342 HydrophobicContact CD1-CB 3.98Å; L303-H342 HydrophobicContact CD2-CB 3.75Å; L303-Q344 HydrophobicContact CD1-CB 3.8Å; L303-Q344 VanDerWaalsContact CD1-N 3.25Å; L303-L393 HydrophobicContact CD1-CD1 3.91Å; L303-L393 HydrophobicContact CD2-CD1 4.02Å; L303-L393 HydrophobicContact CG-CD1 4.33Å; L303-K451 WeakPolarHBondContact O-CE 3.34Å; L303-K451 PolarHBondContact O-NZ 3.34Å; L303-Q456 PolarHBondContact O-NE2 2.98Å
304S93.5Very high92.5Very high23 Ų2355.9 Ų55.916%0.16126%0.259CS..  trans-101132.1-176177.80000112.3C302 R306 R309 K451C302-S304 PolarHBondContact O-N 3.11Å; S304-R306 PolarHBondContact OG-N 3.18Å; S304-R309 CarbonylContact O-C 3.6Å; S304-R309 WeakPolarHBondContact O-CB 3.29Å; S304-K451 VanDerWaalsContact CA-NZ 3.34Å
305C92.8Very high92.7Very high37 Ų3755 Ų5525%0.2525%0.251CS..  trans-95.1-6.5170.7-73.70000114.5K307 N308 C310 Q456C305-K307 PolarHBondContact O-N 2.87Å; C305-N308 PolarHBondContact O-N 3.36Å; C305-C310 WeakPolarHBondContact CA-SG 3.05Å; C305-C310 HydrophobicContact CB-CB 3.96Å; C305-C310 WeakPolarHBondContact CB-SG 3.08Å; C305-C310 WeakPolarHBondContact SG-CB 3.34Å; C305-C310 CovalentContact SG-SG 2.03Å; C305-C310 PolarHBondContact SG-SG 3.3Å; C305-Q456 HydrophobicContact CB-CG 4.05Å; C305-Q456 VanDerWaalsContact N-OE1 3.13Å
306R90.3Very high92.8Very high193 Ų19352.5 Ų52.573%0.72824%0.237SC*.G310 helixtrans-59.9137.5179.8-65.1-177.1177.6-170.8-4.2111.5S304 N308 R309S304-R306 PolarHBondContact OG-N 3.18Å; R306-N308 VanDerWaalsContact C-N 3.32Å; R306-N308 PolarHBondContact O-N 2.78Å; R306-R309 WeakPolarHBondContact O-CB 3.32Å; R306-R309 VanDerWaalsContact O-CG 3.27Å; R306-R309 WeakPolarHBondContact O-CG 3.45Å; R306-R309 PolarHBondContact O-N 2.61Å
307K87.1Confident92.8Very high190 Ų19047.3 Ų47.383%0.82622%0.219SC*.G310 helixtrans55.543.5179.2-56.6-177.6176.2-173.50112.5C305 R309C305-K307 PolarHBondContact O-N 2.87Å; K307-R309 PolarHBondContact O-N 3.03Å
308N86.4Confident92.7Very high87 Ų8755.7 Ų55.747%0.46525%0.251SS..G310 helixtrans59.128.8179.4-52.7-17000114C305 R306 C310 M320C305-N308 PolarHBondContact O-N 3.36Å; R306-N308 VanDerWaalsContact C-N 3.32Å; R306-N308 PolarHBondContact O-N 2.78Å; N308-C310 PolarHBondContact O-N 3.19Å; N308-M320 HydrophobicContact CB-SD 4.21Å
309R91.7Very high92.5Very high130 Ų13058.2 Ų58.249%0.49126%0.262SS..  trans-76.12174.3-73.4-175.8-171.6-169.32113.6Q290 S304 R306 K307Q290-R309 HydrophobicContact CB-CB 4.34Å; Q290-R309 WeakPolarHBondContact CB-O 3.43Å; Q290-R309 PolarHBondContact N-O 3.03Å; S304-R309 CarbonylContact O-C 3.6Å; S304-R309 WeakPolarHBondContact O-CB 3.29Å; R306-R309 WeakPolarHBondContact O-CB 3.32Å; R306-R309 VanDerWaalsContact O-CG 3.27Å; R306-R309 WeakPolarHBondContact O-CG 3.45Å; R306-R309 PolarHBondContact O-N 2.61Å; K307-R309 PolarHBondContact O-N 3.03Å
310C93.8Very high92.3Very high21 Ų2156.6 Ų56.614%0.14226%0.255CS..EExtended strand (participates in β ladder)trans-133.9155.9166.580.20000109.2A288 Y289 C305 N308A288-C310 CarbonylContact O-C 3.58Å; A288-C310 WeakPolarHBondContact O-CA 3.24Å; A288-C310 WeakPolarHBondContact O-CB 3.28Å; Y289-C310 HydrophobicContact CD1-CB 3.73Å; Y289-C310 HydrophobicContact CE1-CB 4.01Å; C305-C310 WeakPolarHBondContact CA-SG 3.05Å; C305-C310 HydrophobicContact CB-CB 3.96Å; C305-C310 WeakPolarHBondContact CB-SG 3.08Å; C305-C310 WeakPolarHBondContact SG-CB 3.34Å; C305-C310 CovalentContact SG-SG 2.03Å; C305-C310 PolarHBondContact SG-SG 3.3Å; N308-C310 PolarHBondContact O-N 3.19Å
311N94.3Very high91.4Very high15 Ų1568 Ų688%0.0830%0.299CS..EExtended strand (participates in β ladder)trans-146.4160.6179.7-149.2-20.4000109.7Y287 A288 R318 M328Y287-N311 CarbonylContact C-O 3.58Å; Y287-N311 WeakPolarHBondContact CA-O 3.19Å; A288-N311 PolarHBondContact N-O 3.1Å; A288-N311 PolarHBondContact O-N 2.86Å; N311-R318 PolarHBondContact ND2-O 3.4Å; N311-R318 PolarHBondContact OD1-N 3.34Å; N311-R318 VanDerWaalsContact OD1-N 3.14Å; N311-M328 HydrophobicContact CB-CE 3.95Å; N311-M328 HydrophobicContact CB-SD 3.69Å
312N93.7Very high90.1Very high22 Ų2273.6 Ų73.612%0.11832%0.32CS..EExtended strand (participates in β ladder)trans-70.7156.4166-58-52.5000109.3Y287 N316 A317Y287-N312 VanDerWaalsContact CE1-OD1 3.27Å; Y287-N312 WeakPolarHBondContact CE1-OD1 3.42Å; N312-N316 HydrophobicContact CB-CB 3.92Å; N312-N316 WeakPolarHBondContact CB-O 3.5Å; N312-N316 PolarHBondContact ND2-O 3.46Å; N312-N316 VanDerWaalsContact ND2-O 3.09Å; N312-A317 WeakPolarHBondContact O-CA 3.39Å; N312-A317 VanDerWaalsContact O-CB 3.32Å; N312-A317 WeakPolarHBondContact O-CB 3.49Å
313I93.4Very high88.4Confident6 Ų681.8 Ų81.83%0.03135%0.349CS..  trans-94.7157.1169.475.1176.3000111.2I237 L274 S278 S286 A288 L330I237-I313 HydrophobicContact CD1-CB 4.21Å; I237-I313 HydrophobicContact CD1-CG2 4.09Å; I237-I313 HydrophobicContact CG2-CG2 4.04Å; L274-I313 HydrophobicContact CD2-CD1 4.38Å; S278-I313 WeakPolarHBondContact CB-O 3.37Å; S286-I313 VanDerWaalsContact CB-CD1 3.43Å; S286-I313 PolarHBondContact O-N 3.08Å; A288-I313 HydrophobicContact CB-CG2 3.76Å; I313-L330 HydrophobicContact CD1-CD1 3.91Å; I313-L330 HydrophobicContact CG2-CD1 3.88Å; I313-L330 HydrophobicContact CG2-CD2 4.17Å
314G94.3Very high87.1Confident0 Ų088.9 Ų88.90%038%0.376CS..G310 helixtrans64.2-136.417400000113.3R183 S278 N316 A317R183-G314 PolarHBondContact NH2-O 2.99Å; S278-G314 WeakPolarHBondContact OG-CA 3.48Å; G314-N316 VanDerWaalsContact C-N 3.27Å; G314-N316 PolarHBondContact O-N 3.38Å; G314-N316 VanDerWaalsContact O-N 3.12Å; G314-A317 WeakPolarHBondContact O-CB 3.45Å; G314-A317 PolarHBondContact O-N 3.17Å
315Y95.3Very high86.3Confident21 Ų2190.7 Ų90.78%0.08238%0.384CS..G310 helixtrans-57.6-36.3-168.1-165.5-104.5000114K79 R107 E108 H159 R183 F275 S278 L279 A317K79-Y315 PolarHBondContact NZ-OH 3.21Å; R107-Y315 HydrophobicContact CG-CD1 4.33Å; R107-Y315 HydrophobicContact CG-CE1 4.24Å; E108-Y315 HydrophobicContact CG-CE1 4.41Å; E108-Y315 WeakPolarHBondContact CG-OH 3.37Å; E108-Y315 VanDerWaalsContact OE1-CE1 3.22Å; E108-Y315 WeakPolarHBondContact OE1-CE1 3.48Å; E108-Y315 PolarHBondContact OE1-OH 3.44Å; H159-Y315 AromaticContact ND1-CE2 3.88Å; R183-Y315 PolarHBondContact NH1-O 3.27Å; F275-Y315 HydrophobicContact CE1-CD2 4.35Å; F275-Y315 AromaticContact CZ-CD2 3.87Å; F275-Y315 HydrophobicContact CZ-CD2 3.87Å; S278-Y315 PolarHBondContact OG-N 3.18Å; L279-Y315 VanDerWaalsContact CD2-CB 3.49Å; L279-Y315 HydrophobicContact CD2-CD1 3.87Å; L279-Y315 HydrophobicContact CD2-CD2 3.49Å; L279-Y315 VanDerWaalsContact CD2-CD2 3.49Å; L279-Y315 HydrophobicContact CD2-CE2 4.19Å; L279-Y315 HydrophobicContact CD2-CG 3.31Å; L279-Y315 HydrophobicContact CG-CG 4.37Å; Y315-A317 VanDerWaalsContact C-N 3.3Å; Y315-A317 PolarHBondContact O-N 3.07Å
316N93.5Very high86.2Confident36 Ų3689 Ų8919%0.19337%0.372CS..G310 helixtrans-87.35.5-178.4-57.2-58000113.9R107 S278 N312 G314R107-N316 PolarHBondContact NH2-OD1 3.22Å; S278-N316 PolarHBondContact O-ND2 3.09Å; N312-N316 HydrophobicContact CB-CB 3.92Å; N312-N316 WeakPolarHBondContact CB-O 3.5Å; N312-N316 PolarHBondContact ND2-O 3.46Å; N312-N316 VanDerWaalsContact ND2-O 3.09Å; G314-N316 VanDerWaalsContact C-N 3.27Å; G314-N316 PolarHBondContact O-N 3.38Å; G314-N316 VanDerWaalsContact O-N 3.12Å
317A94.2Very high86.4Confident7 Ų783.3 Ų83.36%0.05835%0.353CS..  trans-62145.3174.700000111F210 I235 N312 G314 Y315F210-A317 HydrophobicContact CE1-CB 4.46Å; F210-A317 HydrophobicContact CZ-CB 4.32Å; I235-A317 HydrophobicContact CD1-CB 3.79Å; N312-A317 WeakPolarHBondContact O-CA 3.39Å; N312-A317 VanDerWaalsContact O-CB 3.32Å; N312-A317 WeakPolarHBondContact O-CB 3.49Å; G314-A317 WeakPolarHBondContact O-CB 3.45Å; G314-A317 PolarHBondContact O-N 3.17Å; Y315-A317 VanDerWaalsContact C-N 3.3Å; Y315-A317 PolarHBondContact O-N 3.07Å
318R91.1Very high86.9Confident180 Ų18074.3 Ų74.368%0.67931%0.314SS*.  trans-126.3140-174.3-60.2-176.9-179.2-173.2-1.5111.9F210 N311 M320F210-R318 VanDerWaalsContact CZ-C 3.5Å; N311-R318 PolarHBondContact ND2-O 3.4Å; N311-R318 PolarHBondContact OD1-N 3.34Å; N311-R318 VanDerWaalsContact OD1-N 3.14Å; R318-M320 PolarHBondContact O-N 3.05Å
319K88.8Confident87.4Confident116 Ų11670.5 Ų70.550%0.50429%0.293SS..  trans-55.2132.9171.9-167.7178.2-169.6172.30111D209 F210D209-K319 WeakPolarHBondContact O-CD 3.44Å; D209-K319 WeakPolarHBondContact O-CE 3.31Å; D209-K319 PolarHBondContact O-NZ 3.41Å; F210-K319 HydrophobicContact CB-CB 4.28Å; F210-K319 HydrophobicContact CB-CD 4.43Å; F210-K319 HydrophobicContact CD2-CB 3.66Å; F210-K319 HydrophobicContact CD2-CG 3.9Å; F210-K319 HydrophobicContact CE2-CB 4.11Å; F210-K319 HydrophobicContact CG-CB 3.9Å; F210-K319 HydrophobicContact CG-CG 4.41Å
320M85.4Confident87.6Confident21 Ų2164.3 Ų64.310%0.10327%0.27CS..  trans-93.4135.4178.6-62.2-159.3-65.200111.1I235 N308 R318 K322 S326 M328I235-M320 HydrophobicContact CG2-CE 3.81Å; I235-M320 HydrophobicContact CG2-CG 4.16Å; N308-M320 HydrophobicContact CB-SD 4.21Å; R318-M320 PolarHBondContact O-N 3.05Å; M320-K322 PolarHBondContact O-N 2.03Å; M320-K322 VanDerWaalsContact O-N 3.07Å; M320-S326 WeakPolarHBondContact CE-OG 3.47Å; M320-M328 HydrophobicContact CE-CE 3.72Å; M320-M328 HydrophobicContact SD-CE 3.47Å; M320-M328 WeakPolarHBondContact SD-CE 3.44Å
321R74.9Confident87.7Confident241 Ų24166 Ų6691%0.90928%0.275SS*.SBendtrans-57.5-22.7-177.2-87.9-177.5169.7157.4-2.8115.9
322K65.9Low87.7Confident184 Ų18465.5 Ų65.580%0.827%0.272SS*.SBendtrans-149.2132.8-179-68.9-165.8176.8-168.60111.5M320M320-K322 PolarHBondContact O-N 2.03Å; M320-K322 VanDerWaalsContact O-N 3.07Å
323R60.1Low87.7Confident187 Ų18767 Ų6771%0.70628%0.276SS*.  trans95.1110.1178.6-63.2-178.5166.2177.2-8.6114.8S326R323-S326 PolarHBondContact O-OG 3.07Å
324R69.1Low87.6Confident150 Ų15068.4 Ų68.457%0.56629%0.288SS*.SBendtrans-60.8150.4154.1-65-177.5-180-164.6-8.2109D206D206-R324 VanDerWaalsContact CG-NH1 3.34Å; D206-R324 IonicContact OD1-CZ 3.04Å; D206-R324 IonicContact OD1-NH1 3.67Å; D206-R324 PolarHBondContact OD1-NH1 2.79Å; D206-R324 IonicContact OD1-NH2 4Å; D206-R324 PolarHBondContact OD1-NH2 2.05Å; D206-R324 IonicContact OD2-CZ 2.8Å; D206-R324 IonicContact OD2-NH1 2.58Å; D206-R324 PolarHBondContact OD2-NH1 2.86Å; D206-R324 IonicContact OD2-NH2 3.79Å
325N77.2Confident87.3Confident61 Ų6176.3 Ų76.333%0.32632%0.322SS..SBendtrans62.748.7172.5-52.51.3000114.1P205 P231 G233 D234 K327P205-N325 WeakPolarHBondContact CG-OD1 3.19Å; P231-N325 HydrophobicContact CB-CB 4.02Å; P231-N325 HydrophobicContact CG-CB 4.08Å; G233-N325 WeakPolarHBondContact O-CA 3.41Å; G233-N325 PolarHBondContact O-N 3.25Å; G233-N325 VanDerWaalsContact O-N 3.13Å; G233-N325 PolarHBondContact O-OD1 3.07Å; G233-N325 VanDerWaalsContact O-OD1 3.07Å; D234-N325 PolarHBondContact O-N 2.81Å; N325-K327 PolarHBondContact O-N 2.83Å
326S89.7Confident87Confident2 Ų279.4 Ų79.41%0.01434%0.344CS..EExtended strand (participates in β ladder)trans-83.4101.2178.4-73.90000112.2D234 D236 Q290 M320 R323 M328D234-S326 PolarHBondContact O-N 2.81Å; D234-S326 VanDerWaalsContact O-N 3.12Å; D236-S326 PolarHBondContact N-O 2.83Å; Q290-S326 PolarHBondContact NE2-OG 2.81Å; M320-S326 WeakPolarHBondContact CE-OG 3.47Å; R323-S326 PolarHBondContact O-OG 3.07Å; S326-M328 PolarHBondContact O-N 2.92Å
327K95.1Very high86.9Confident73 Ų7379.5 Ų79.532%0.31735%0.346SS..EExtended strand (participates in β ladder)trans-66.3124.7172.6-57.1-167.5178-1690112.3P231 D236 Y238 Q290 C291 N325 Y329P231-K327 HydrophobicContact CB-CG 4.36Å; P231-K327 VanDerWaalsContact CG-CE 3.49Å; D236-K327 CarbonylContact O-C 3.53Å; D236-K327 WeakPolarHBondContact O-CA 3.36Å; Y238-K327 HydrophobicContact CD2-CB 4.49Å; Y238-K327 HydrophobicContact CE2-CB 4.13Å; Y238-K327 HydrophobicContact CE2-CD 4.14Å; Y238-K327 HydrophobicContact CE2-CG 3.92Å; Q290-K327 WeakPolarHBondContact CA-O 3.44Å; C291-K327 PolarHBondContact N-O 3.26Å; C291-K327 VanDerWaalsContact N-O 3.08Å; N325-K327 PolarHBondContact O-N 2.83Å; K327-Y329 HydrophobicContact CB-CE2 4.02Å
328M96.3Very high86.8Confident0 Ų079.8 Ų79.80%035%0.346CS..EExtended strand (participates in β ladder)trans-127.6151178.5-59.6-166.2146.400111.2D236 I237 Y238 A288 Y289 Q290 N311 M320 S326D236-M328 PolarHBondContact O-N 2.96Å; I237-M328 CarbonylContact C-O 3.58Å; I237-M328 WeakPolarHBondContact CA-O 2.94Å; I237-M328 HydrophobicContact CG1-CB 4.16Å; Y238-M328 PolarHBondContact N-O 3.32Å; A288-M328 HydrophobicContact CB-CB 3.72Å; A288-M328 HydrophobicContact CB-SD 4.28Å; Y289-M328 CarbonylContact O-C 3.59Å; Y289-M328 VanDerWaalsContact O-CA 3.31Å; Y289-M328 WeakPolarHBondContact O-CA 3.13Å; Q290-M328 HydrophobicContact CB-CE 3.94Å; Q290-M328 HydrophobicContact CB-CG 4.34Å; N311-M328 HydrophobicContact CB-CE 3.95Å; N311-M328 HydrophobicContact CB-SD 3.69Å; M320-M328 HydrophobicContact CE-CE 3.72Å; M320-M328 HydrophobicContact SD-CE 3.47Å; M320-M328 WeakPolarHBondContact SD-CE 3.44Å; S326-M328 PolarHBondContact O-N 2.92Å
329Y97.3Very high86.9Confident8 Ų871.6 Ų71.63%0.03132%0.317CS..EExtended strand (participates in β ladder)trans-137.5150-175-58.1-93.1000110.8Y238 Y289 C291 P294 F297 K327Y238-Y329 HydrophobicContact CD2-CE1 4.19Å; Y238-Y329 HydrophobicContact CG-CE1 4.05Å; Y289-Y329 PolarHBondContact N-O 3.2Å; Y289-Y329 PolarHBondContact O-N 3.26Å; C291-Y329 HydrophobicContact CB-CD2 3.5Å; C291-Y329 VanDerWaalsContact CB-CD2 3.5Å; C291-Y329 HydrophobicContact CB-CE2 3.82Å; P294-Y329 HydrophobicContact CB-CD1 4.26Å; P294-Y329 HydrophobicContact CB-CE1 3.89Å; P294-Y329 HydrophobicContact CG-CE1 4.42Å; F297-Y329 HydrophobicContact CB-CD2 4.4Å; F297-Y329 HydrophobicContact CB-CG 4.14Å; F297-Y329 HydrophobicContact CD1-CG 4.43Å; F297-Y329 WeakPolarHBondContact CE2-O 3.39Å; F297-Y329 VanDerWaalsContact CG-CB 3.43Å; F297-Y329 HydrophobicContact CG-CG 4.18Å; K327-Y329 HydrophobicContact CB-CE2 4.02Å
330L96.9Very high87Confident0 Ų066.6 Ų66.60%030%0.299CS..EExtended strand (participates in β ladder)trans-150.3164.8171.870.3165.4000109.9I237 P239 N240 Y287 A288 F297 I313 T332I237-L330 HydrophobicContact CG2-CD2 3.46Å; I237-L330 VanDerWaalsContact CG2-CD2 3.46Å; P239-L330 HydrophobicContact CB-CD2 3.97Å; P239-L330 HydrophobicContact CG-CD2 3.94Å; N240-L330 WeakPolarHBondContact CA-O 3.37Å; N240-L330 PolarHBondContact N-O 2.72Å; Y287-L330 WeakPolarHBondContact O-CB 3.46Å; A288-L330 HydrophobicContact CB-CD2 4.12Å; F297-L330 VanDerWaalsContact CZ-CA 3.41Å; I313-L330 HydrophobicContact CD1-CD1 3.91Å; I313-L330 HydrophobicContact CG2-CD1 3.88Å; I313-L330 HydrophobicContact CG2-CD2 4.17Å; L330-T332 HydrophobicContact CD1-CG2 3.78Å; L330-T332 HydrophobicContact CG-CG2 3.98Å
331K95.4Very high87.4Confident57 Ų5767.9 Ų67.925%0.24830%0.303CS..  trans-101.1148.9161-74.7-63.7-175.1-174.60109.2N240 F297 H342 L393 F395N240-K331 HydrophobicContact CB-CD 4.44Å; N240-K331 PolarHBondContact O-NZ 3.2Å; N240-K331 VanDerWaalsContact O-NZ 3.15Å; N240-K331 WeakPolarHBondContact OD1-CA 3.28Å; N240-K331 VanDerWaalsContact OD1-CD 3.31Å; N240-K331 WeakPolarHBondContact OD1-CD 3.47Å; F297-K331 HydrophobicContact CE1-CG 4.2Å; K331-H342 PolarHBondContact N-NE2 3.45Å; K331-H342 PolarHBondContact O-NE2 3.4Å; K331-L393 HydrophobicContact CG-CD2 4.03Å; K331-F395 HydrophobicContact CB-CB 3.96Å; K331-F395 HydrophobicContact CB-CD1 3.99Å; K331-F395 HydrophobicContact CB-CD2 3.45Å; K331-F395 VanDerWaalsContact CB-CD2 3.45Å; K331-F395 HydrophobicContact CB-CE1 4.34Å; K331-F395 HydrophobicContact CB-CE2 3.84Å; K331-F395 HydrophobicContact CB-CG 3.52Å; K331-F395 HydrophobicContact CB-CZ 4.27Å; K331-F395 HydrophobicContact CG-CB 4.16Å; K331-F395 HydrophobicContact CG-CG 4.25Å; K331-F395 WeakPolarHBondContact O-CE2 3.08Å
332T94.8Very high88.4Confident3 Ų356.5 Ų56.52%0.01826%0.26CS..  trans-131.4162.2177.670.10000110.5P239 N240 L274 L330 F338P239-T332 HydrophobicContact CB-CG2 4.23Å; N240-T332 PolarHBondContact ND2-OG1 3.16Å; N240-T332 PolarHBondContact OD1-N 3.01Å; L274-T332 HydrophobicContact CD2-CG2 3.95Å; L330-T332 HydrophobicContact CD1-CG2 3.78Å; L330-T332 HydrophobicContact CG-CG2 3.98Å; T332-F338 CarbonylContact C-O 3.55Å; T332-F338 WeakPolarHBondContact CA-O 3.37Å; T332-F338 WeakPolarHBondContact CB-O 3.48Å
333R92.8Very high89.9Confident55 Ų5548.3 Ų48.321%0.20823%0.225CC..  trans-74.4164.4172.1-56.5-179.251.1-160.319.8111.1R270 K335 P337 F338 G339 F395 E397R270-R333 PolarHBondContact NH1-O 3.37Å; R333-K335 VanDerWaalsContact C-N 3.33Å; R333-P337 VanDerWaalsContact CD-O 3.25Å; R333-P337 WeakPolarHBondContact CD-O 3.37Å; R333-P337 PolarHBondContact NH1-O 3.13Å; R333-F338 PolarHBondContact N-O 3.38Å; R333-G339 WeakPolarHBondContact CD-O 3.37Å; R333-G339 WeakPolarHBondContact CG-O 3.21Å; R333-F395 HydrophobicContact CG-CE1 4.42Å; R333-F395 HydrophobicContact CG-CZ 4.14Å; R333-E397 HydrophobicContact CB-CG 4.47Å; R333-E397 HydrophobicContact CG-CB 3.93Å; R333-E397 VanDerWaalsContact CG-CD 3.47Å; R333-E397 HydrophobicContact CG-CG 3.65Å; R333-E397 IonicContact CZ-OE2 3.74Å; R333-E397 IonicContact NE-OE2 3.73Å; R333-E397 PolarHBondContact NE-OE2 3.32Å; R333-E397 IonicContact NH2-OE2 3.03Å; R333-E397 PolarHBondContact NH2-OE2 3.4Å
334A90.7Very high91.6Very high34 Ų3440.3 Ų40.328%0.28120%0.195SC..SBendtrans-69.9-30.8174.200000113.1P246 R270P246-A334 HydrophobicContact CB-CB 4.05Å; P246-A334 VanDerWaalsContact O-CA 3.32Å; P246-A334 WeakPolarHBondContact O-CA 3.1Å; R270-A334 PolarHBondContact NH1-O 2.69Å; R270-A334 VanDerWaalsContact NH1-O 3.09Å; R270-A334 PolarHBondContact NH2-O 2.79Å; R270-A334 VanDerWaalsContact NH2-O 3.09Å
335K89.3Confident92.8Very high166 Ų16633.2 Ų33.272%0.72217%0.168SC*.SBendtrans-129.9159.4-174.9-62.4-177.8-178.8179.90111.2R333 P337 F338R333-K335 VanDerWaalsContact C-N 3.33Å; K335-P337 CarbonylContact O-C 3.33Å; K335-P337 VanDerWaalsContact O-O 3.09Å; K335-F338 VanDerWaalsContact O-CD1 3.3Å; K335-F338 WeakPolarHBondContact O-CD1 3.34Å
336T87.9Confident93.6Very high87 Ų8734.1 Ų34.153%0.53417%0.169SC..SBendtrans-68.6145.3175.8179.90000111D277 F338D277-T336 PolarHBondContact OD1-OG1 3.47Å; T336-F338 VanDerWaalsContact N-CE1 3.3Å
337P92.4Very high93.8Very high38 Ų3834.2 Ų34.225%0.24717%0.169CC..SBendcis-65.7135.1-8.126.9-32.8000111D277 H284 R333 K335 G339D277-P337 WeakPolarHBondContact OD1-CA 3.35Å; H284-P337 HydrophobicContact CB-CB 4.42Å; R333-P337 VanDerWaalsContact CD-O 3.25Å; R333-P337 WeakPolarHBondContact CD-O 3.37Å; R333-P337 PolarHBondContact NH1-O 3.13Å; K335-P337 CarbonylContact O-C 3.33Å; K335-P337 VanDerWaalsContact O-O 3.09Å; P337-G339 VanDerWaalsContact C-N 3.34Å; P337-G339 PolarHBondContact O-N 3.43Å
338F92.5Very high93.6Very high13 Ų1333.3 Ų33.36%0.05717%0.166CC..  trans-81.5-14.6-169.4-65.8-61.9000113.9H273 L274 D277 T332 R333 K335 T336H273-F338 HydrophobicContact CB-CE2 3.81Å; H273-F338 HydrophobicContact CB-CZ 3.99Å; H273-F338 WeakPolarHBondContact O-CE2 3.39Å; L274-F338 HydrophobicContact CD2-CB 3.67Å; L274-F338 HydrophobicContact CD2-CD2 3.76Å; L274-F338 HydrophobicContact CD2-CG 3.79Å; L274-F338 HydrophobicContact CG-CD2 4.5Å; D277-F338 HydrophobicContact CB-CD2 3.58Å; D277-F338 HydrophobicContact CB-CE2 4.1Å; D277-F338 PolarHBondContact OD1-N 2.93Å; D277-F338 PolarHBondContact OD2-N 2.81Å; D277-F338 VanDerWaalsContact OD2-N 3.14Å; T332-F338 CarbonylContact C-O 3.55Å; T332-F338 WeakPolarHBondContact CA-O 3.37Å; T332-F338 WeakPolarHBondContact CB-O 3.48Å; R333-F338 PolarHBondContact N-O 3.38Å; K335-F338 VanDerWaalsContact O-CD1 3.3Å; K335-F338 WeakPolarHBondContact O-CD1 3.34Å; T336-F338 VanDerWaalsContact N-CE1 3.3Å
339G91.7Very high93.2Very high7 Ų733.3 Ų33.37%0.07217%0.166CC..  trans-64.6158.2179.700000113.8S286 R333 P337S286-G339 WeakPolarHBondContact OG-CA 3.46Å; R333-G339 WeakPolarHBondContact CD-O 3.37Å; R333-G339 WeakPolarHBondContact CG-O 3.21Å; P337-G339 VanDerWaalsContact C-N 3.34Å; P337-G339 PolarHBondContact O-N 3.43Å
340G92.1Very high92.7Very high12 Ų1235.9 Ų35.912%0.12418%0.178CC..  trans-167.3-172.6175.600000110.8T396G340-T396 WeakPolarHBondContact CA-O 3.34Å
341Y94Very high92Very high48 Ų4838.3 Ų38.319%0.18819%0.191CC..EExtended strand (participates in β ladder)trans-113.6133-168.1-57.4-84000112F395 T396 E398 D399 E454Y341-F395 WeakPolarHBondContact O-CA 3.35Å; Y341-T396 HydrophobicContact CD2-CG2 4.47Å; Y341-T396 PolarHBondContact N-O 2.92Å; Y341-T396 PolarHBondContact O-N 3.1Å; Y341-E398 VanDerWaalsContact CD2-O 3.24Å; Y341-E398 WeakPolarHBondContact CD2-O 3.44Å; Y341-D399 VanDerWaalsContact CE2-CA 3.44Å; Y341-D399 HydrophobicContact CE2-CB 3.74Å; Y341-D399 WeakPolarHBondContact OH-CB 3.41Å; Y341-E454 WeakPolarHBondContact CA-OE2 3.19Å; Y341-E454 HydrophobicContact CD1-CB 4.34Å; Y341-E454 HydrophobicContact CD1-CG 4.02Å
342H96Very high90.8Very high2 Ų241.9 Ų41.91%0.00920%0.203CC..EExtended strand (participates in β ladder)trans-108123-175.2-59.983.6000110.8Y289 F297 L303 K331 L393 F395 G453 E454Y289-H342 HydrophobicContact CE2-CB 4.28Å; Y289-H342 AromaticContact CE2-CG 3.97Å; Y289-H342 AromaticContact CE2-ND1 3.85Å; F297-H342 AromaticContact CZ-CD2 3.91Å; L303-H342 HydrophobicContact CD1-CB 3.98Å; L303-H342 HydrophobicContact CD2-CB 3.75Å; K331-H342 PolarHBondContact N-NE2 3.45Å; K331-H342 PolarHBondContact O-NE2 3.4Å; H342-L393 HydrophobicContact CB-CD1 4.15Å; H342-F395 AromaticContact CD2-CD2 4Å; H342-F395 AromaticContact NE2-CD2 3.84Å; H342-G453 PolarHBondContact O-N 3.49Å; H342-E454 IonicContact CE1-OE1 3.97Å; H342-E454 IonicContact CG-OE1 3.43Å; H342-E454 PolarHBondContact N-OE1 2.84Å; H342-E454 PolarHBondContact N-OE2 3.43Å; H342-E454 IonicContact ND1-OE1 3.77Å; H342-E454 PolarHBondContact ND1-OE1 3.24Å
343Y95.8Very high89.5Confident12 Ų1247.8 Ų47.85%0.04723%0.228CC..EExtended strand (participates in β ladder)trans-120.1121177-61.8-87.4000110.1L366 V394 T396 I400 V450 K451 A452Y343-L366 HydrophobicContact CD2-CD1 4.11Å; Y343-L366 HydrophobicContact CE2-CD1 4.19Å; Y343-V394 PolarHBondContact N-O 3.26Å; Y343-V394 PolarHBondContact O-N 3.45Å; Y343-T396 HydrophobicContact CD2-CG2 4.33Å; Y343-T396 HydrophobicContact CE2-CG2 3.74Å; Y343-I400 HydrophobicContact CE2-CD1 4.41Å; Y343-V450 HydrophobicContact CD1-CG1 3.84Å; Y343-V450 HydrophobicContact CG-CG1 4.48Å; Y343-K451 WeakPolarHBondContact CA-O 3.44Å; Y343-A452 HydrophobicContact CD1-CB 3.93Å; Y343-A452 HydrophobicContact CE1-CB 3.73Å
344Q96.1Very high88.1Confident19 Ų1953 Ų539%0.08926%0.255CS..EExtended strand (participates in β ladder)trans-81.2123.4163.3175.8179.147.500107.7G300 L303 K346 T391 V450 K451G300-Q344 VanDerWaalsContact O-CB 3.28Å; G300-Q344 WeakPolarHBondContact O-CB 3.41Å; G300-Q344 VanDerWaalsContact O-CG 3.25Å; G300-Q344 WeakPolarHBondContact O-CG 3.1Å; G300-Q344 PolarHBondContact O-NE2 3.37Å; L303-Q344 HydrophobicContact CD1-CB 3.8Å; L303-Q344 VanDerWaalsContact CD1-N 3.25Å; Q344-K346 HydrophobicContact CG-CG 4.3Å; Q344-T391 PolarHBondContact NE2-OG1 3.38Å; Q344-V450 CarbonylContact O-C 3.55Å; Q344-V450 VanDerWaalsContact O-CA 3.24Å; Q344-V450 WeakPolarHBondContact O-CA 3.46Å; Q344-K451 HydrophobicContact CB-CB 4.23Å; Q344-K451 PolarHBondContact N-O 2.98Å; Q344-K451 PolarHBondContact O-N 2.84Å
345M94.9Very high86.8Confident0 Ų051.9 Ų51.90%024%0.244CC..EExtended strand (participates in β ladder)trans-114.9136.5173.2-63.8-155.5174.900110.2V364 L366 T391 F392 V394 I406 I448 R449 V450M345-V364 HydrophobicContact CE-CG1 4.16Å; M345-V364 HydrophobicContact SD-CG1 4.25Å; M345-L366 HydrophobicContact CE-CD1 4.39Å; M345-L366 HydrophobicContact CE-CD2 3.35Å; M345-L366 HydrophobicContact CE-CG 4.48Å; M345-T391 VanDerWaalsContact O-CA 3.3Å; M345-T391 WeakPolarHBondContact O-CA 3.37Å; M345-F392 HydrophobicContact CB-CD1 4.3Å; M345-F392 HydrophobicContact CB-CD2 3.66Å; M345-F392 HydrophobicContact CB-CE1 3.79Å; M345-F392 HydrophobicContact CB-CE2 3.14Å; M345-F392 HydrophobicContact CB-CG 4.21Å; M345-F392 HydrophobicContact CB-CZ 3.17Å; M345-F392 HydrophobicContact CG-CD2 4.34Å; M345-F392 HydrophobicContact CG-CE2 3.77Å; M345-F392 HydrophobicContact CG-CZ 4.15Å; M345-F392 PolarHBondContact N-O 2.84Å; M345-F392 WeakPolarHBondContact O-CD1 3.07Å; M345-F392 PolarHBondContact O-N 3.14Å; M345-F392 HydrophobicContact SD-CE2 3.62Å; M345-F392 HydrophobicContact SD-CZ 4.05Å; M345-V394 HydrophobicContact CB-CG2 4.45Å; M345-V394 HydrophobicContact CE-CB 4.29Å; M345-V394 HydrophobicContact CE-CG1 4.44Å; M345-V394 HydrophobicContact CE-CG2 4.1Å; M345-V394 HydrophobicContact CG-CB 4.48Å; M345-V394 HydrophobicContact CG-CG2 3.84Å; M345-V394 HydrophobicContact SD-CG2 3.74Å; M345-I406 HydrophobicContact CE-CD1 4.2Å; M345-I448 HydrophobicContact CB-CG2 4.34Å; M345-I448 HydrophobicContact SD-CG2 4.36Å; M345-R449 CarbonylContact C-O 3.36Å; M345-R449 WeakPolarHBondContact CA-O 3.42Å; M345-V450 HydrophobicContact CE-CG2 4.25Å; M345-V450 HydrophobicContact CG-CG2 4.11Å; M345-V450 HydrophobicContact SD-CG2 4.43Å
346K94.5Very high85.2Confident81 Ų8150 Ų5035%0.35224%0.242SC..EExtended strand (participates in β ladder)trans-126.5121.6176.1-57.5-171177.7-166.30109.5Q344 T389 N390 I448 R449Q344-K346 HydrophobicContact CG-CG 4.3Å; K346-T389 HydrophobicContact CB-CG2 4.11Å; K346-N390 VanDerWaalsContact CA-O 3.29Å; K346-N390 WeakPolarHBondContact CA-O 3.32Å; K346-I448 CarbonylContact O-C 3.58Å; K346-I448 WeakPolarHBondContact O-CA 3.42Å; K346-R449 HydrophobicContact CB-CB 4.31Å; K346-R449 PolarHBondContact N-O 3.34Å; K346-R449 PolarHBondContact O-N 3Å
347M92.6Very high83.6Confident3 Ų352.7 Ų52.72%0.01525%0.253CS..EExtended strand (participates in β ladder)trans-126139.817474174.176.500109.5V349 T389 N390 F392 L408 I445 I448M347-V349 HydrophobicContact CG-CG2 3.95Å; M347-V349 HydrophobicContact SD-CG2 4.03Å; M347-T389 CarbonylContact O-C 3.58Å; M347-T389 WeakPolarHBondContact O-CA 3.36Å; M347-N390 PolarHBondContact N-O 2.98Å; M347-N390 PolarHBondContact O-N 2.9Å; M347-F392 HydrophobicContact CB-CE1 4.47Å; M347-F392 HydrophobicContact CE-CE1 3.39Å; M347-F392 HydrophobicContact CE-CE2 4.24Å; M347-F392 HydrophobicContact CE-CZ 3.19Å; M347-F392 HydrophobicContact CG-CE1 3.95Å; M347-F392 HydrophobicContact SD-CE1 4.39Å; M347-L408 HydrophobicContact CE-CD1 3.81Å; M347-L408 HydrophobicContact CE-CD2 3.78Å; M347-L408 HydrophobicContact CE-CG 4.46Å; M347-L408 HydrophobicContact SD-CD2 4Å; M347-I445 HydrophobicContact CB-CG2 4.08Å; M347-I445 HydrophobicContact SD-CD1 3.61Å; M347-I445 HydrophobicContact SD-CG1 4.3Å; M347-I445 HydrophobicContact SD-CG2 4.28Å; M347-I448 HydrophobicContact CB-CG1 4.21Å
348H90.7Very high82Confident55 Ų5553.1 Ų53.126%0.25526%0.259SS..EExtended strand (participates in β ladder)trans-93.3125.3170.4-167.693.2000108.2F350 N387 F388 T389H348-F350 HydrophobicContact CB-CE2 4.43Å; H348-F350 AromaticContact CD2-CD1 3.61Å; H348-F350 AromaticContact CD2-CD2 3.72Å; H348-F350 AromaticContact CD2-CE1 3.3Å; H348-F350 WeakPolarHBondContact CD2-CE1 3.15Å; H348-F350 AromaticContact CD2-CE2 3.41Å; H348-F350 VanDerWaalsContact CD2-CE2 3.41Å; H348-F350 WeakPolarHBondContact CD2-CE2 3.18Å; H348-F350 AromaticContact CD2-CG 3.81Å; H348-F350 AromaticContact CD2-CZ 3.19Å; H348-F350 WeakPolarHBondContact CD2-CZ 3.42Å; H348-F350 AromaticContact NE2-CD1 3.65Å; H348-F350 AromaticContact NE2-CE1 3.35Å; H348-F350 WeakPolarHBondContact NE2-CE1 3.35Å; H348-F350 AromaticContact NE2-CZ 3.73Å; H348-N387 PolarHBondContact CE1-O 3.3Å; H348-N387 VanDerWaalsContact CE1-O 3.23Å; H348-N387 PolarHBondContact NE2-O 3.38Å; H348-F388 WeakPolarHBondContact CA-O 3.14Å; H348-T389 PolarHBondContact ND1-OG1 2.85Å; H348-T389 VanDerWaalsContact ND1-OG1 3.16Å
349V88.8Confident81.1Confident0 Ų055.3 Ų55.30%027%0.271CS..EExtended strand (participates in β ladder)trans-107.2112.3-176.3176.40000108M347 I384 L386 N387 F388 L443 I445M347-V349 HydrophobicContact CG-CG2 3.95Å; M347-V349 HydrophobicContact SD-CG2 4.03Å; V349-I384 HydrophobicContact CB-CG2 4.33Å; V349-I384 HydrophobicContact CG1-CG2 4.24Å; V349-I384 HydrophobicContact CG2-CG2 4Å; V349-L386 HydrophobicContact CG1-CD2 4.29Å; V349-N387 WeakPolarHBondContact O-CA 3.24Å; V349-N387 PolarHBondContact O-N 2.77Å; V349-F388 PolarHBondContact N-O 2.9Å; V349-L443 HydrophobicContact CG1-CB 4.17Å; V349-L443 HydrophobicContact CG1-CD1 4.02Å; V349-L443 HydrophobicContact CG1-CD2 3.89Å; V349-L443 HydrophobicContact CG1-CG 4.25Å; V349-I445 HydrophobicContact CG2-CD1 4.44Å; V349-I445 HydrophobicContact CG2-CG1 4.24Å
350F87Confident80.5Confident61 Ų6155 Ų5527%0.26827%0.268SS..EExtended strand (participates in β ladder)trans-92.4134.7176.8-59.9-86.4000110.1H348 N387 E444 R446H348-F350 HydrophobicContact CB-CE2 4.43Å; H348-F350 AromaticContact CD2-CD1 3.61Å; H348-F350 AromaticContact CD2-CD2 3.72Å; H348-F350 AromaticContact CD2-CE1 3.3Å; H348-F350 WeakPolarHBondContact CD2-CE1 3.15Å; H348-F350 AromaticContact CD2-CE2 3.41Å; H348-F350 VanDerWaalsContact CD2-CE2 3.41Å; H348-F350 WeakPolarHBondContact CD2-CE2 3.18Å; H348-F350 AromaticContact CD2-CG 3.81Å; H348-F350 AromaticContact CD2-CZ 3.19Å; H348-F350 WeakPolarHBondContact CD2-CZ 3.42Å; H348-F350 AromaticContact NE2-CD1 3.65Å; H348-F350 AromaticContact NE2-CE1 3.35Å; H348-F350 WeakPolarHBondContact NE2-CE1 3.35Å; H348-F350 AromaticContact NE2-CZ 3.73Å; F350-N387 WeakPolarHBondContact CA-OD1 3.46Å; F350-E444 HydrophobicContact CB-CB 4.08Å; F350-E444 HydrophobicContact CD2-CG 4.38Å; F350-E444 WeakPolarHBondContact CD2-O 3.42Å; F350-E444 PolarHBondContact N-O 2.8Å; F350-E444 PolarHBondContact O-N 3.27Å; F350-R446 HydrophobicContact CE2-CG 4.22Å
351N81.1Confident80.3Confident51 Ų5155.4 Ų55.427%0.27327%0.269SS..EExtended strand (participates in β ladder)trans-84.7120.4175.2-174.59.2000109.9L386 N387N351-L386 HydrophobicContact CB-CB 4.12Å; N351-L386 HydrophobicContact CB-CD1 4.02Å; N351-L386 HydrophobicContact CB-CD2 4.22Å; N351-L386 HydrophobicContact CB-CG 4.35Å; N351-L386 WeakPolarHBondContact ND2-CD1 3.42Å; N351-N387 PolarHBondContact N-OD1 2.92Å
352R71.2Confident80.1Confident132 Ų13253.2 Ų53.250%0.49826%0.26SS..EExtended strand (participates in β ladder)trans-109.1-43.6-176.9-86.4-81.1-173.6153.28.9113.7E444 E470R352-E444 HydrophobicContact CG-CB 3.96Å; R352-E444 IonicContact CZ-OE2 3.51Å; R352-E444 VanDerWaalsContact CZ-OE2 3.26Å; R352-E444 IonicContact NE-OE2 3.94Å; R352-E444 PolarHBondContact NE-OE2 3.36Å; R352-E444 IonicContact NH2-OE1 2.69Å; R352-E444 IonicContact NH2-OE2 3.62Å; R352-E444 PolarHBondContact NH2-OE2 3.03Å; R352-E470 IonicContact NE-OE1 3.65Å
353K66.8Low80Confident127 Ų12755.9 Ų55.955%0.55227%0.27SS*.EExtended strand (participates in β ladder)trans-14295.9-174.1-64.8-179.6-175.9167.90111F355 V442K353-F355 PolarHBondContact O-N 3.18Å; K353-V442 HydrophobicContact CB-CB 4.28Å; K353-V442 HydrophobicContact CB-CG2 4.48Å; K353-V442 HydrophobicContact CD-CB 4.5Å; K353-V442 HydrophobicContact CD-CG2 4.22Å
354Q64.3Low80Confident165 Ų16555.3 Ų55.377%0.77127%0.268SS*.  trans33.871.5170.9-80.3177.7-18.800115.5D356Q354-D356 PolarHBondContact O-N 3.09Å
355F63.8Low80Confident11 Ų1157 Ų575%0.04828%0.275CS..  trans-94.359.4170.6-166.1-99.3000111.2K353 N357 A358 P360 L386 W410 P441 L443K353-F355 PolarHBondContact O-N 3.18Å; F355-N357 VanDerWaalsContact C-N 3.31Å; F355-N357 PolarHBondContact O-N 2.82Å; F355-A358 HydrophobicContact CD2-CB 4.08Å; F355-A358 HydrophobicContact CE1-CB 4.31Å; F355-A358 WeakPolarHBondContact CE1-O 3.3Å; F355-A358 HydrophobicContact CE2-CB 3.35Å; F355-A358 HydrophobicContact CZ-CB 3.5Å; F355-A358 WeakPolarHBondContact CZ-O 3.25Å; F355-P360 HydrophobicContact CZ-CB 4.42Å; F355-P360 HydrophobicContact CZ-CG 4.2Å; F355-L386 HydrophobicContact CB-CD1 4.1Å; F355-L386 HydrophobicContact CD1-CD1 3.72Å; F355-L386 HydrophobicContact CD1-CD2 3.58Å; F355-L386 HydrophobicContact CD1-CG 4.04Å; F355-L386 HydrophobicContact CE1-CD2 4.03Å; F355-L386 HydrophobicContact CG-CD1 4.35Å; F355-L386 HydrophobicContact CG-CD2 4.26Å; F355-W410 HydrophobicContact CD2-CH2 4.24Å; F355-W410 AromaticContact CE2-CH2 3.58Å; F355-W410 HydrophobicContact CE2-CH2 3.58Å; F355-W410 AromaticContact CE2-CZ2 3.78Å; F355-W410 HydrophobicContact CE2-CZ2 3.78Å; F355-W410 HydrophobicContact CZ-CZ2 4.47Å; F355-P441 HydrophobicContact CD2-CB 3.48Å; F355-P441 VanDerWaalsContact CD2-CB 3.48Å; F355-P441 HydrophobicContact CD2-CG 4.47Å; F355-P441 HydrophobicContact CE2-CB 3.93Å; F355-L443 HydrophobicContact CB-CD2 4.41Å; F355-L443 HydrophobicContact CD1-CD2 4.36Å; F355-L443 HydrophobicContact CD2-CD2 3.97Å; F355-L443 HydrophobicContact CD2-CG 4.44Å; F355-L443 HydrophobicContact CE2-CD1 4.28Å; F355-L443 HydrophobicContact CE2-CD2 4.25Å; F355-L443 HydrophobicContact CE2-CG 4.4Å; F355-L443 HydrophobicContact CG-CD2 4.01Å; F355-L443 HydrophobicContact CZ-CD1 4.34Å
356D55.9Low80.1Confident126 Ų12657 Ų5767%0.67428%0.275SS*.SBendtrans-82.5-4.4-173.6-72.2-12.1000113.5Q354Q354-D356 PolarHBondContact O-N 3.09Å
357N54.2Low80.2Confident144 Ų14455.1 Ų55.177%0.7727%0.266SS*.SBendtrans-160.520.5-172.1-101.9-17.8000118.4F355F355-N357 VanDerWaalsContact C-N 3.31Å; F355-N357 PolarHBondContact O-N 2.82Å
358A57.5Low80.3Confident46 Ų4655.5 Ų55.538%0.3827%0.271SS..  trans-108146.9175.400000111.1F355F355-A358 HydrophobicContact CD2-CB 4.08Å; F355-A358 HydrophobicContact CE1-CB 4.31Å; F355-A358 WeakPolarHBondContact CE1-O 3.3Å; F355-A358 HydrophobicContact CE2-CB 3.35Å; F355-A358 HydrophobicContact CZ-CB 3.5Å; F355-A358 WeakPolarHBondContact CZ-O 3.25Å
359D73.6Confident80.4Confident59 Ų5955.2 Ų55.232%0.31628%0.283SS..  trans-118.3106170.4-171.625.5000105.8H380 P383 I384D359-H380 IonicContact OD1-CD2 3.32Å; D359-H380 IonicContact OD1-NE2 3.4Å; D359-H380 PolarHBondContact OD1-NE2 3.4Å; D359-H380 IonicContact OD2-CD2 2.66Å; D359-H380 IonicContact OD2-NE2 2.79Å; D359-P383 WeakPolarHBondContact OD1-CA 3.23Å; D359-I384 PolarHBondContact OD1-N 3.42Å
360P80.6Confident80.5Confident1 Ų161.7 Ų61.71%0.00631%0.313CS..  trans-78.4131.6-161.732.2-31.3000111.1F355 F362 H380 I384 W410 L443F355-P360 HydrophobicContact CZ-CB 4.42Å; F355-P360 HydrophobicContact CZ-CG 4.2Å; P360-F362 HydrophobicContact CB-CE1 4.26Å; P360-F362 HydrophobicContact CB-CE2 4.02Å; P360-F362 HydrophobicContact CB-CZ 3.86Å; P360-F362 HydrophobicContact CG-CD2 4.24Å; P360-F362 HydrophobicContact CG-CE2 3.54Å; P360-F362 HydrophobicContact CG-CZ 3.75Å; P360-F362 PolarHBondContact O-N 2.82Å; P360-H380 PolarHBondContact O-CE1 2.88Å; P360-H380 VanDerWaalsContact O-CE1 3.31Å; P360-I384 HydrophobicContact CG-CB 3.91Å; P360-I384 HydrophobicContact CG-CG1 3.73Å; P360-I384 HydrophobicContact CG-CG2 4.22Å; P360-W410 HydrophobicContact CB-CD2 4.19Å; P360-W410 HydrophobicContact CB-CZ2 3.77Å; P360-L443 HydrophobicContact CB-CD1 4.34Å; P360-L443 HydrophobicContact CG-CD1 4.12Å
361T86.8Confident80.8Confident21 Ų2162.9 Ų62.913%0.12932%0.322CS..  trans-83.2105.2171.7-46.80000109.3Y363 F377 E411T361-Y363 HydrophobicContact CG2-CE2 4Å; T361-F377 HydrophobicContact CG2-CD2 3.92Å; T361-F377 HydrophobicContact CG2-CE2 3.39Å; T361-F377 HydrophobicContact CG2-CZ 4.4Å; T361-E411 WeakPolarHBondContact CB-OE2 3.38Å; T361-E411 HydrophobicContact CG2-CB 4.1Å; T361-E411 VanDerWaalsContact CG2-OE2 3.24Å; T361-E411 WeakPolarHBondContact CG2-OE2 3.48Å; T361-E411 PolarHBondContact O-N 2.9Å; T361-E411 PolarHBondContact OG1-OE2 2.85Å
362F90.6Very high81.5Confident1 Ų164 Ų640%0.00433%0.328CS..EExtended strand (participates in β ladder)trans-95.4140.4176.5-68.8-55.2000112.7P360 V378 I384 L408 S409 W410 L443 I445P360-F362 HydrophobicContact CB-CE1 4.26Å; P360-F362 HydrophobicContact CB-CE2 4.02Å; P360-F362 HydrophobicContact CB-CZ 3.86Å; P360-F362 HydrophobicContact CG-CD2 4.24Å; P360-F362 HydrophobicContact CG-CE2 3.54Å; P360-F362 HydrophobicContact CG-CZ 3.75Å; P360-F362 PolarHBondContact O-N 2.82Å; F362-V378 HydrophobicContact CB-CB 4.17Å; F362-V378 HydrophobicContact CB-CG2 4.21Å; F362-V378 WeakPolarHBondContact O-CB 3.32Å; F362-V378 PolarHBondContact O-N 2.99Å; F362-I384 HydrophobicContact CE2-CG1 4.31Å; F362-L408 HydrophobicContact CB-CD1 3.9Å; F362-L408 HydrophobicContact CD1-CD1 3.99Å; F362-L408 HydrophobicContact CD1-CD2 4.46Å; F362-L408 HydrophobicContact CD1-CG 4.22Å; F362-L408 HydrophobicContact CG-CD1 4.02Å; F362-S409 WeakPolarHBondContact CA-O 3.4Å; F362-W410 HydrophobicContact CD1-CB 4.2Å; F362-W410 HydrophobicContact CD1-CG 4.49Å; F362-W410 HydrophobicContact CE1-CB 4.11Å; F362-W410 HydrophobicContact CE1-CD2 4.43Å; F362-W410 HydrophobicContact CE1-CG 4.21Å; F362-L443 HydrophobicContact CZ-CD1 3.95Å; F362-I445 HydrophobicContact CZ-CD1 4.26Å
363Y93.7Very high82.6Confident59 Ų5957.9 Ų57.923%0.23131%0.306CS..EExtended strand (participates in β ladder)trans-115.3142166.2-62.7-86.9000110.1T361 N375 I376 F377 L408 S409 E411T361-Y363 HydrophobicContact CG2-CE2 4Å; Y363-N375 HydrophobicContact CD1-CB 4.32Å; Y363-I376 CarbonylContact C-O 3.17Å; Y363-I376 WeakPolarHBondContact CA-O 3.35Å; Y363-F377 HydrophobicContact CD1-CB 4.13Å; Y363-F377 HydrophobicContact CD1-CD2 4.4Å; Y363-F377 HydrophobicContact CE1-CB 3.95Å; Y363-F377 HydrophobicContact CE1-CD2 4.01Å; Y363-F377 HydrophobicContact CE1-CG 4.39Å; Y363-L408 WeakPolarHBondContact O-CA 3.41Å; Y363-S409 PolarHBondContact N-O 2.95Å; Y363-S409 PolarHBondContact O-N 2.96Å; Y363-E411 HydrophobicContact CE2-CB 3.9Å; Y363-E411 HydrophobicContact CE2-CG 4.13Å; Y363-E411 PolarHBondContact OH-OE1 3.25Å
364V95.3Very high83.9Confident0 Ų054.5 Ų54.50%031%0.306CS..EExtended strand (participates in β ladder)trans-121.2129.5176.6172.80000109.6M345 L366 I376 V378 F392 I406 R407 L408M345-V364 HydrophobicContact CE-CG1 4.16Å; M345-V364 HydrophobicContact SD-CG1 4.25Å; V364-L366 HydrophobicContact CG1-CD2 3.44Å; V364-L366 VanDerWaalsContact CG1-CD2 3.44Å; V364-L366 HydrophobicContact CG1-CG 4.26Å; V364-I376 PolarHBondContact N-O 2.89Å; V364-I376 WeakPolarHBondContact O-CB 3.33Å; V364-I376 PolarHBondContact O-N 2.92Å; V364-V378 HydrophobicContact CB-CG2 4.17Å; V364-V378 HydrophobicContact CG2-CG2 3.49Å; V364-V378 VanDerWaalsContact CG2-CG2 3.49Å; V364-F392 HydrophobicContact CG2-CE2 4.44Å; V364-I406 HydrophobicContact CG1-CG2 3.75Å; V364-R407 CarbonylContact C-O 3.6Å; V364-R407 WeakPolarHBondContact CA-O 3.33Å; V364-L408 HydrophobicContact CG2-CD1 3.71Å
365K96.8Very high85.2Confident55 Ų5551.8 Ų51.824%0.23930%0.297CS..EExtended strand (participates in β ladder)trans-111.7125.5166.4175.3165175.51690109.6Y367 T373 R407K365-Y367 HydrophobicContact CB-CE2 4.31Å; K365-Y367 HydrophobicContact CD-CE1 4.42Å; K365-Y367 HydrophobicContact CD-CE2 4.19Å; K365-Y367 WeakPolarHBondContact CD-OH 3.35Å; K365-Y367 HydrophobicContact CG-CD2 4.38Å; K365-Y367 HydrophobicContact CG-CE2 3.76Å; K365-T373 WeakPolarHBondContact CD-O 3.46Å; K365-T373 WeakPolarHBondContact CE-O 3.36Å; K365-T373 WeakPolarHBondContact CG-O 3.48Å; K365-R407 HydrophobicContact CB-CB 4.35Å; K365-R407 PolarHBondContact N-O 3.43Å; K365-R407 PolarHBondContact O-N 3.3Å
366L96.8Very high86.5Confident0 Ų052.8 Ų52.80%030%0.303CS..EExtended strand (participates in β ladder)trans-97.4134.2178.6-50.4-177.7000109.3Y343 M345 V364 D372 T373 I376 V394 I400 L403 I406Y343-L366 HydrophobicContact CD2-CD1 4.11Å; Y343-L366 HydrophobicContact CE2-CD1 4.19Å; M345-L366 HydrophobicContact CE-CD1 4.39Å; M345-L366 HydrophobicContact CE-CD2 3.35Å; M345-L366 HydrophobicContact CE-CG 4.48Å; V364-L366 HydrophobicContact CG1-CD2 3.44Å; V364-L366 VanDerWaalsContact CG1-CD2 3.44Å; V364-L366 HydrophobicContact CG1-CG 4.26Å; L366-D372 WeakPolarHBondContact O-CA 3.22Å; L366-T373 HydrophobicContact CB-CG2 3.83Å; L366-T373 HydrophobicContact CD1-CG2 4.35Å; L366-T373 HydrophobicContact CG-CG2 4.25Å; L366-T373 PolarHBondContact N-OG1 2.81Å; L366-T373 PolarHBondContact O-N 3.33Å; L366-I376 HydrophobicContact CD1-CD1 4.39Å; L366-I376 HydrophobicContact CG-CD1 4.45Å; L366-V394 HydrophobicContact CD1-CG1 4.33Å; L366-I400 HydrophobicContact CB-CD1 3.86Å; L366-I400 HydrophobicContact CD1-CD1 3.98Å; L366-L403 HydrophobicContact CB-CD1 3.8Å; L366-L403 HydrophobicContact CD2-CD1 4.08Å; L366-L403 HydrophobicContact CG-CD1 4.37Å; L366-I406 HydrophobicContact CD2-CG1 4.23Å; L366-I406 HydrophobicContact CD2-CG2 4.3Å
367Y96.6Very high87.9Confident40 Ų4051.4 Ų51.416%0.15729%0.291CS..EExtended strand (participates in β ladder)trans-111.1122.7175.6-63.1-99000109K365 D372 L404 K405 R407K365-Y367 HydrophobicContact CB-CE2 4.31Å; K365-Y367 HydrophobicContact CD-CE1 4.42Å; K365-Y367 HydrophobicContact CD-CE2 4.19Å; K365-Y367 WeakPolarHBondContact CD-OH 3.35Å; K365-Y367 HydrophobicContact CG-CD2 4.38Å; K365-Y367 HydrophobicContact CG-CE2 3.76Å; Y367-D372 WeakPolarHBondContact CA-OD1 3.11Å; Y367-D372 HydrophobicContact CD1-CB 4.42Å; Y367-D372 VanDerWaalsContact CD1-CG 3.46Å; Y367-D372 WeakPolarHBondContact CD1-OD2 3.45Å; Y367-L404 PolarHBondContact O-N 3.28Å; Y367-K405 HydrophobicContact CD2-CB 4.2Å; Y367-K405 HydrophobicContact CD2-CD 4.29Å; Y367-K405 HydrophobicContact CD2-CG 3.75Å; Y367-K405 HydrophobicContact CE2-CG 4.36Å; Y367-K405 HydrophobicContact CG-CB 4.29Å; Y367-K405 HydrophobicContact CG-CG 4.21Å; Y367-K405 PolarHBondContact N-O 3.11Å; Y367-K405 PolarHBondContact O-N 2.84Å; Y367-R407 HydrophobicContact CE2-CB 3.8Å
368G94.8Very high89.3Confident12 Ų1244.7 Ų44.712%0.12426%0.255CS..  trans-108.7178.1-171.700000114N371 D372 I400 L404G368-N371 VanDerWaalsContact CA-O 3.26Å; G368-N371 WeakPolarHBondContact CA-O 3.39Å; G368-N371 PolarHBondContact N-O 2.92Å; G368-N371 VanDerWaalsContact N-O 3.17Å; G368-D372 PolarHBondContact N-OD1 2.92Å; G368-I400 CarbonylContact C-O 3.55Å; G368-I400 WeakPolarHBondContact CA-O 3.34Å; G368-L404 WeakPolarHBondContact O-CD1 3.5Å
369G93.1Very high90.1Very high49 Ų4946.8 Ų46.851%0.50526%0.263SS..SBendtrans-82.3-25.3168.800000113.1I400 D402G369-I400 PolarHBondContact N-O 3.38Å; G369-D402 PolarHBondContact N-O 2.85Å; G369-D402 VanDerWaalsContact N-O 3.14Å
370H90.9Very high90Very high136 Ų13646.2 Ų46.263%0.6326%0.258SS*.SBendtrans-102.1-61.2178.4-60.5169.5000110.8D399 I400H370-D399 IonicContact ND1-OD2 3.35Å; H370-I400 PolarHBondContact N-O 3.01Å
371N92.8Very high89.2Confident85 Ų8549.2 Ų49.246%0.45528%0.283SS..  trans-131.8164.8-178.9-76.9-16.6000111.8G368 I400G368-N371 VanDerWaalsContact CA-O 3.26Å; G368-N371 WeakPolarHBondContact CA-O 3.39Å; G368-N371 PolarHBondContact N-O 2.92Å; G368-N371 VanDerWaalsContact N-O 3.17Å; N371-I400 WeakPolarHBondContact O-CA 3.29Å; N371-I400 WeakPolarHBondContact O-CB 3.24Å; N371-I400 WeakPolarHBondContact O-CG2 3.41Å
372D95.3Very high88.5Confident75 Ų7552.4 Ų52.440%0.40130%0.299SS..BIsolated β-bridgetrans-107.7153.6169.4-67.3-17.1000110.4L366 Y367 G368L366-D372 WeakPolarHBondContact O-CA 3.22Å; Y367-D372 WeakPolarHBondContact CA-OD1 3.11Å; Y367-D372 HydrophobicContact CD1-CB 4.42Å; Y367-D372 VanDerWaalsContact CD1-CG 3.46Å; Y367-D372 WeakPolarHBondContact CD1-OD2 3.45Å; G368-D372 PolarHBondContact N-OD1 2.92Å
373T95.1Very high88Confident4 Ų457.1 Ų57.13%0.02533%0.33CS..  trans-85.9163.6174.271.70000112K365 L366 I376 T396 I400K365-T373 WeakPolarHBondContact CD-O 3.46Å; K365-T373 WeakPolarHBondContact CE-O 3.36Å; K365-T373 WeakPolarHBondContact CG-O 3.48Å; L366-T373 HydrophobicContact CB-CG2 3.83Å; L366-T373 HydrophobicContact CD1-CG2 4.35Å; L366-T373 HydrophobicContact CG-CG2 4.25Å; L366-T373 PolarHBondContact N-OG1 2.81Å; L366-T373 PolarHBondContact O-N 3.33Å; T373-I376 HydrophobicContact CG2-CD1 4.01Å; T373-T396 HydrophobicContact CG2-CG2 4.44Å; T373-T396 VanDerWaalsContact CG2-OG1 3.28Å; T373-T396 WeakPolarHBondContact CG2-OG1 3.38Å; T373-I400 HydrophobicContact CG2-CG2 3.68Å
374G93.4Very high87.4Confident55 Ų5555.2 Ų55.257%0.56732%0.324SS*.  trans-65.8-175.5155.200000112.4I376G374-I376 PolarHBondContact O-N 3.49Å
375N91.2Very high86.8Confident108 Ų10856.3 Ų56.358%0.57834%0.335SS*.  trans-72.5114169.9-73.7-18.9000109.2Y363Y363-N375 HydrophobicContact CD1-CB 4.32Å
376I91.8Very high86.2Confident32 Ų3256.4 Ų56.416%0.16434%0.338CS..EExtended strand (participates in β ladder)trans-93.8122.5178.2-55.1169.8000108.2Y363 V364 L366 T373 G374 V378 V394Y363-I376 CarbonylContact C-O 3.17Å; Y363-I376 WeakPolarHBondContact CA-O 3.35Å; V364-I376 PolarHBondContact N-O 2.89Å; V364-I376 WeakPolarHBondContact O-CB 3.33Å; V364-I376 PolarHBondContact O-N 2.92Å; L366-I376 HydrophobicContact CD1-CD1 4.39Å; L366-I376 HydrophobicContact CG-CD1 4.45Å; T373-I376 HydrophobicContact CG2-CD1 4.01Å; G374-I376 PolarHBondContact O-N 3.49Å; I376-V378 PolarHBondContact O-N 3.01Å; I376-V394 HydrophobicContact CD1-CG1 3.92Å; I376-V394 HydrophobicContact CG2-CG1 4.1Å
377F86.1Confident85.7Confident98 Ų9861 Ų6143%0.4336%0.362SS..EExtended strand (participates in β ladder)trans-68.1129.5174.1175.6-122000111T361 Y363 V379T361-F377 HydrophobicContact CG2-CD2 3.92Å; T361-F377 HydrophobicContact CG2-CE2 3.39Å; T361-F377 HydrophobicContact CG2-CZ 4.4Å; Y363-F377 HydrophobicContact CD1-CB 4.13Å; Y363-F377 HydrophobicContact CD1-CD2 4.4Å; Y363-F377 HydrophobicContact CE1-CB 3.95Å; Y363-F377 HydrophobicContact CE1-CD2 4.01Å; Y363-F377 HydrophobicContact CE1-CG 4.39Å; F377-V379 HydrophobicContact CD1-CG2 3.74Å; F377-V379 HydrophobicContact CE1-CB 4.49Å; F377-V379 HydrophobicContact CE1-CG2 3.82Å; F377-V379 PolarHBondContact O-N 3.23Å
378V82.4Confident85.3Confident3 Ų365.3 Ų65.32%0.01838%0.382CS..  trans-87.696.9177.7-179.10000109.8F362 V364 I376 H380 F392F362-V378 HydrophobicContact CB-CB 4.17Å; F362-V378 HydrophobicContact CB-CG2 4.21Å; F362-V378 WeakPolarHBondContact O-CB 3.32Å; F362-V378 PolarHBondContact O-N 2.99Å; V364-V378 HydrophobicContact CB-CG2 4.17Å; V364-V378 HydrophobicContact CG2-CG2 3.49Å; V364-V378 VanDerWaalsContact CG2-CG2 3.49Å; I376-V378 PolarHBondContact O-N 3.01Å; V378-H380 PolarHBondContact O-N 3.34Å; V378-H380 PolarHBondContact O-ND1 3.38Å; V378-F392 HydrophobicContact CB-CD2 4.42Å; V378-F392 HydrophobicContact CG1-CB 3.75Å; V378-F392 HydrophobicContact CG1-CD1 4.31Å; V378-F392 HydrophobicContact CG1-CD2 3.34Å; V378-F392 HydrophobicContact CG1-CE2 3.95Å; V378-F392 HydrophobicContact CG1-CG 3.55Å; V378-F392 HydrophobicContact CG2-CD2 4.19Å; V378-F392 HydrophobicContact CG2-CE2 4.14Å
379V74.4Confident85.1Confident89 Ų8967.9 Ų67.954%0.53940%0.396SS..  trans-69.1119.3174-1740000109.6F377F377-V379 HydrophobicContact CD1-CG2 3.74Å; F377-V379 HydrophobicContact CE1-CB 4.49Å; F377-V379 HydrophobicContact CE1-CG2 3.82Å; F377-V379 PolarHBondContact O-N 3.23Å
380H71.1Confident85Confident48 Ų4866.6 Ų66.622%0.22238%0.377CS..  trans-119.8133.9172.448.3-81.1000109.3D359 P360 V378 D382 I384D359-H380 IonicContact OD1-CD2 3.32Å; D359-H380 IonicContact OD1-NE2 3.4Å; D359-H380 PolarHBondContact OD1-NE2 3.4Å; D359-H380 IonicContact OD2-CD2 2.66Å; D359-H380 IonicContact OD2-NE2 2.79Å; P360-H380 PolarHBondContact O-CE1 2.88Å; P360-H380 VanDerWaalsContact O-CE1 3.31Å; V378-H380 PolarHBondContact O-N 3.34Å; V378-H380 PolarHBondContact O-ND1 3.38Å; H380-D382 PolarHBondContact CD2-O 2.74Å; H380-I384 HydrophobicContact CB-CD1 4.26Å
381A64.4Low85.1Confident64 Ų6461.9 Ų61.953%0.52936%0.358SS..SBendtrans-86.5-25.7-178.400000112.7
382D73.1Confident85.1Confident88 Ų8858.2 Ų58.247%0.47134%0.338SS..SBendtrans-116153.7176.7-48.3-41.4000108.6K299 H380K299-D382 WeakPolarHBondContact CE-OD2 3.33Å; K299-D382 IonicContact NZ-OD1 3.54Å; K299-D382 IonicContact NZ-OD2 2.76Å; K299-D382 PolarHBondContact NZ-OD2 2.91Å; H380-D382 PolarHBondContact CD2-O 2.74Å
383P78.4Confident85Confident99 Ų9955.4 Ų55.464%0.64332%0.323SS*.  trans-53144.2170.9-24.133.5000111.4D359 G385D359-P383 WeakPolarHBondContact OD1-CA 3.23Å; P383-G385 PolarHBondContact O-N 3.37Å
384I82.1Confident85Confident20 Ų2055.4 Ų55.410%0.10332%0.323CS..  trans-62.5114178.7-65.5-62.1000110.2V349 D359 P360 F362 H380 L386 N390V349-I384 HydrophobicContact CB-CG2 4.33Å; V349-I384 HydrophobicContact CG1-CG2 4.24Å; V349-I384 HydrophobicContact CG2-CG2 4Å; D359-I384 PolarHBondContact OD1-N 3.42Å; P360-I384 HydrophobicContact CG-CB 3.91Å; P360-I384 HydrophobicContact CG-CG1 3.73Å; P360-I384 HydrophobicContact CG-CG2 4.22Å; F362-I384 HydrophobicContact CE2-CG1 4.31Å; H380-I384 HydrophobicContact CB-CD1 4.26Å; I384-L386 PolarHBondContact O-N 2.93Å; I384-N390 HydrophobicContact CD1-CB 4.27Å
385G81.8Confident85Confident23 Ų2354.5 Ų54.524%0.23730%0.303CS..  trans-69.1128.417900000111.5P383 N390P383-G385 PolarHBondContact O-N 3.37Å; G385-N390 PolarHBondContact N-OD1 3.28Å; G385-N390 PolarHBondContact O-ND2 2.82Å
386L84.6Confident85.1Confident56 Ų5649.8 Ų49.829%0.29328%0.278SS..THydrogen-bonded Turntrans-82.4144.5176-62.1-179.8000111.8V349 N351 F355 I384 F388 L443V349-L386 HydrophobicContact CG1-CD2 4.29Å; N351-L386 HydrophobicContact CB-CB 4.12Å; N351-L386 HydrophobicContact CB-CD1 4.02Å; N351-L386 HydrophobicContact CB-CD2 4.22Å; N351-L386 HydrophobicContact CB-CG 4.35Å; N351-L386 WeakPolarHBondContact ND2-CD1 3.42Å; F355-L386 HydrophobicContact CB-CD1 4.1Å; F355-L386 HydrophobicContact CD1-CD1 3.72Å; F355-L386 HydrophobicContact CD1-CD2 3.58Å; F355-L386 HydrophobicContact CD1-CG 4.04Å; F355-L386 HydrophobicContact CE1-CD2 4.03Å; F355-L386 HydrophobicContact CG-CD1 4.35Å; F355-L386 HydrophobicContact CG-CD2 4.26Å; I384-L386 PolarHBondContact O-N 2.93Å; L386-F388 PolarHBondContact O-N 3.21Å; L386-F388 VanDerWaalsContact O-N 3.11Å; L386-L443 HydrophobicContact CD2-CD2 3.82Å
387N86.9Confident85.1Confident97 Ų9752.2 Ų52.252%0.51929%0.289SS..THydrogen-bonded Turntrans50.631.2-171.4-57.1-36.8000111.9H348 V349 F350 N351H348-N387 PolarHBondContact CE1-O 3.3Å; H348-N387 VanDerWaalsContact CE1-O 3.23Å; H348-N387 PolarHBondContact NE2-O 3.38Å; V349-N387 WeakPolarHBondContact O-CA 3.24Å; V349-N387 PolarHBondContact O-N 2.77Å; F350-N387 WeakPolarHBondContact CA-OD1 3.46Å; N351-N387 PolarHBondContact N-OD1 2.92Å
388F87.6Confident85.3Confident130 Ų13051.5 Ų51.557%0.5729%0.287SS*.EExtended strand (participates in β ladder)trans-132.6157.2-173.1-163-100.1000111.1H348 V349 L386 N390H348-F388 WeakPolarHBondContact CA-O 3.14Å; V349-F388 PolarHBondContact N-O 2.9Å; L386-F388 PolarHBondContact O-N 3.21Å; L386-F388 VanDerWaalsContact O-N 3.11Å; F388-N390 PolarHBondContact O-ND2 3.18Å
389T90.6Very high85.7Confident67 Ų6754.4 Ų54.441%0.41130%0.302SS..EExtended strand (participates in β ladder)trans-91.5106.4175.9-51.70000109.9K346 M347 H348K346-T389 HydrophobicContact CB-CG2 4.11Å; M347-T389 CarbonylContact O-C 3.58Å; M347-T389 WeakPolarHBondContact O-CA 3.36Å; H348-T389 PolarHBondContact ND1-OG1 2.85Å; H348-T389 VanDerWaalsContact ND1-OG1 3.16Å
390N91.4Very high86.6Confident21 Ų2150.1 Ų50.111%0.11228%0.277CS..EExtended strand (participates in β ladder)trans-85.5139.8176.6-63.4-76.9000109.7K346 M347 I384 G385 F388K346-N390 VanDerWaalsContact CA-O 3.29Å; K346-N390 WeakPolarHBondContact CA-O 3.32Å; M347-N390 PolarHBondContact N-O 2.98Å; M347-N390 PolarHBondContact O-N 2.9Å; I384-N390 HydrophobicContact CD1-CB 4.27Å; G385-N390 PolarHBondContact N-OD1 3.28Å; G385-N390 PolarHBondContact O-ND2 2.82Å; F388-N390 PolarHBondContact O-ND2 3.18Å
391T92.9Very high87.6Confident38 Ų3848.9 Ų48.923%0.23328%0.277CS..EExtended strand (participates in β ladder)trans-126.9133.4-179.3-178.20000109.4K299 I301 Q344 M345K299-T391 HydrophobicContact CB-CG2 4.11Å; K299-T391 CarbonylContact O-C 3.59Å; K299-T391 PolarHBondContact O-OG1 3.45Å; I301-T391 HydrophobicContact CD1-CG2 4.4Å; I301-T391 HydrophobicContact CG1-CG2 4.18Å; Q344-T391 PolarHBondContact NE2-OG1 3.38Å; M345-T391 VanDerWaalsContact O-CA 3.3Å; M345-T391 WeakPolarHBondContact O-CA 3.37Å
392F91.6Very high88.8Confident7 Ų749.7 Ų49.73%0.03127%0.272CS..EExtended strand (participates in β ladder)trans-141.8148.5-175.147.6-79.2000110K299 M345 M347 V364 V378 V394K299-F392 PolarHBondContact O-N 2.83Å; M345-F392 HydrophobicContact CB-CD1 4.3Å; M345-F392 HydrophobicContact CB-CD2 3.66Å; M345-F392 HydrophobicContact CB-CE1 3.79Å; M345-F392 HydrophobicContact CB-CE2 3.14Å; M345-F392 HydrophobicContact CB-CG 4.21Å; M345-F392 HydrophobicContact CB-CZ 3.17Å; M345-F392 HydrophobicContact CG-CD2 4.34Å; M345-F392 HydrophobicContact CG-CE2 3.77Å; M345-F392 HydrophobicContact CG-CZ 4.15Å; M345-F392 PolarHBondContact N-O 2.84Å; M345-F392 WeakPolarHBondContact O-CD1 3.07Å; M345-F392 PolarHBondContact O-N 3.14Å; M345-F392 HydrophobicContact SD-CE2 3.62Å; M345-F392 HydrophobicContact SD-CZ 4.05Å; M347-F392 HydrophobicContact CB-CE1 4.47Å; M347-F392 HydrophobicContact CE-CE1 3.39Å; M347-F392 HydrophobicContact CE-CE2 4.24Å; M347-F392 HydrophobicContact CE-CZ 3.19Å; M347-F392 HydrophobicContact CG-CE1 3.95Å; M347-F392 HydrophobicContact SD-CE1 4.39Å; V364-F392 HydrophobicContact CG2-CE2 4.44Å; V378-F392 HydrophobicContact CB-CD2 4.42Å; V378-F392 HydrophobicContact CG1-CB 3.75Å; V378-F392 HydrophobicContact CG1-CD1 4.31Å; V378-F392 HydrophobicContact CG1-CD2 3.34Å; V378-F392 HydrophobicContact CG1-CE2 3.95Å; V378-F392 HydrophobicContact CG1-CG 3.55Å; V378-F392 HydrophobicContact CG2-CD2 4.19Å; V378-F392 HydrophobicContact CG2-CE2 4.14Å; F392-V394 HydrophobicContact CD2-CG2 3.52Å; F392-V394 HydrophobicContact CE2-CG2 3.69Å
393L94.3Very high89.9Confident17 Ų1745.7 Ų45.79%0.08925%0.251CS..EExtended strand (participates in β ladder)trans-86.8126168.3-177.866.4000108.4F297 K298 L303 K331 H342F297-L393 HydrophobicContact CD1-CD2 4.1Å; F297-L393 HydrophobicContact CE1-CD2 3.57Å; F297-L393 HydrophobicContact CE2-CD2 4.3Å; F297-L393 HydrophobicContact CZ-CD2 3.65Å; K298-L393 WeakPolarHBondContact O-CB 3.48Å; K298-L393 PolarHBondContact O-N 3.22Å; L303-L393 HydrophobicContact CD1-CD1 3.91Å; L303-L393 HydrophobicContact CD2-CD1 4.02Å; L303-L393 HydrophobicContact CG-CD1 4.33Å; K331-L393 HydrophobicContact CG-CD2 4.03Å; H342-L393 HydrophobicContact CB-CD1 4.15Å
394V94.9Very high90.6Very high3 Ų344.9 Ų44.92%0.01824%0.241CC..EExtended strand (participates in β ladder)trans-109.4122.7167.3-179.90000107Y343 M345 L366 I376 F392Y343-V394 PolarHBondContact N-O 3.26Å; Y343-V394 PolarHBondContact O-N 3.45Å; M345-V394 HydrophobicContact CB-CG2 4.45Å; M345-V394 HydrophobicContact CE-CB 4.29Å; M345-V394 HydrophobicContact CE-CG1 4.44Å; M345-V394 HydrophobicContact CE-CG2 4.1Å; M345-V394 HydrophobicContact CG-CB 4.48Å; M345-V394 HydrophobicContact CG-CG2 3.84Å; M345-V394 HydrophobicContact SD-CG2 3.74Å; L366-V394 HydrophobicContact CD1-CG1 4.33Å; I376-V394 HydrophobicContact CD1-CG1 3.92Å; I376-V394 HydrophobicContact CG2-CG1 4.1Å; F392-V394 HydrophobicContact CD2-CG2 3.52Å; F392-V394 HydrophobicContact CE2-CG2 3.69Å
395F94.1Very high91.2Very high37 Ų3746.5 Ų46.516%0.16225%0.247CC..EExtended strand (participates in β ladder)trans-109.9138.7175.1172.9-103.1000109K331 R333 Y341 H342 E397K331-F395 HydrophobicContact CB-CB 3.96Å; K331-F395 HydrophobicContact CB-CD1 3.99Å; K331-F395 HydrophobicContact CB-CD2 3.45Å; K331-F395 VanDerWaalsContact CB-CD2 3.45Å; K331-F395 HydrophobicContact CB-CE1 4.34Å; K331-F395 HydrophobicContact CB-CE2 3.84Å; K331-F395 HydrophobicContact CB-CG 3.52Å; K331-F395 HydrophobicContact CB-CZ 4.27Å; K331-F395 HydrophobicContact CG-CB 4.16Å; K331-F395 HydrophobicContact CG-CG 4.25Å; K331-F395 WeakPolarHBondContact O-CE2 3.08Å; R333-F395 HydrophobicContact CG-CE1 4.42Å; R333-F395 HydrophobicContact CG-CZ 4.14Å; Y341-F395 WeakPolarHBondContact O-CA 3.35Å; H342-F395 AromaticContact CD2-CD2 4Å; H342-F395 AromaticContact NE2-CD2 3.84Å; F395-E397 HydrophobicContact CE1-CG 4.16Å
396T93.1Very high92Very high8 Ų845.4 Ų45.45%0.04924%0.236CC..EExtended strand (participates in β ladder)trans-136143.2173.5-174.80000110.9G340 Y341 Y343 T373 E398G340-T396 WeakPolarHBondContact CA-O 3.34Å; Y341-T396 HydrophobicContact CD2-CG2 4.47Å; Y341-T396 PolarHBondContact N-O 2.92Å; Y341-T396 PolarHBondContact O-N 3.1Å; Y343-T396 HydrophobicContact CD2-CG2 4.33Å; Y343-T396 HydrophobicContact CE2-CG2 3.74Å; T373-T396 HydrophobicContact CG2-CG2 4.44Å; T373-T396 VanDerWaalsContact CG2-OG1 3.28Å; T373-T396 WeakPolarHBondContact CG2-OG1 3.38Å; T396-E398 PolarHBondContact OG1-N 3.15Å
397E90.8Very high92.6Very high83 Ų8347.2 Ų47.239%0.38824%0.238SC..SBendtrans-81.1-20.8176.5-49-154.4164.500112.4R333 F395R333-E397 HydrophobicContact CB-CG 4.47Å; R333-E397 HydrophobicContact CG-CB 3.93Å; R333-E397 VanDerWaalsContact CG-CD 3.47Å; R333-E397 HydrophobicContact CG-CG 3.65Å; R333-E397 IonicContact CZ-OE2 3.74Å; R333-E397 IonicContact NE-OE2 3.73Å; R333-E397 PolarHBondContact NE-OE2 3.32Å; R333-E397 IonicContact NH2-OE2 3.03Å; R333-E397 PolarHBondContact NH2-OE2 3.4Å; F395-E397 HydrophobicContact CE1-CG 4.16Å
398E90.1Very high93Very high83 Ų8342.6 Ų42.639%0.38821%0.214SC..SBendtrans-87.4134-172.9-62-63.2155.300111.3Y341 T396 I400Y341-E398 VanDerWaalsContact CD2-O 3.24Å; Y341-E398 WeakPolarHBondContact CD2-O 3.44Å; T396-E398 PolarHBondContact OG1-N 3.15Å; E398-I400 HydrophobicContact CB-CG2 4.16Å; E398-I400 PolarHBondContact O-N 3.43Å; E398-I400 VanDerWaalsContact O-N 3.08Å
399D90.9Very high93.3Very high64 Ų6437.5 Ų37.534%0.34220%0.195SC..  trans-75.396.2164.6-17711.8000109.8Y341 H370 G401Y341-D399 VanDerWaalsContact CE2-CA 3.44Å; Y341-D399 HydrophobicContact CE2-CB 3.74Å; Y341-D399 WeakPolarHBondContact OH-CB 3.41Å; H370-D399 IonicContact ND1-OD2 3.35Å; D399-G401 VanDerWaalsContact C-N 3.26Å; D399-G401 PolarHBondContact OD1-N 3.41Å
400I93.3Very high93.4Very high0 Ų035 Ų350%018%0.178CC..  trans-81.2-5.9177.466.7171.4000112.5Y343 L366 G368 G369 H370 N371 T373 E398 L403Y343-I400 HydrophobicContact CE2-CD1 4.41Å; L366-I400 HydrophobicContact CB-CD1 3.86Å; L366-I400 HydrophobicContact CD1-CD1 3.98Å; G368-I400 CarbonylContact C-O 3.55Å; G368-I400 WeakPolarHBondContact CA-O 3.34Å; G369-I400 PolarHBondContact N-O 3.38Å; H370-I400 PolarHBondContact N-O 3.01Å; N371-I400 WeakPolarHBondContact O-CA 3.29Å; N371-I400 WeakPolarHBondContact O-CB 3.24Å; N371-I400 WeakPolarHBondContact O-CG2 3.41Å; T373-I400 HydrophobicContact CG2-CG2 3.68Å; E398-I400 HydrophobicContact CB-CG2 4.16Å; E398-I400 PolarHBondContact O-N 3.43Å; E398-I400 VanDerWaalsContact O-N 3.08Å; I400-L403 HydrophobicContact CD1-CB 4.37Å; I400-L403 HydrophobicContact CD1-CD1 3.8Å
401G91.9Very high93.2Very high22 Ų2235 Ų3523%0.22718%0.177CC..  trans61.2-136.8-170.200000112.1D399 L403D399-G401 VanDerWaalsContact C-N 3.26Å; D399-G401 PolarHBondContact OD1-N 3.41Å; G401-L403 PolarHBondContact O-N 3.36Å
402D91.4Very high92.6Very high81 Ų8133.6 Ų33.643%0.43317%0.17SC..SBendtrans-73.6120.7177.7-82.5-34.1000111.5G369 L404 K457G369-D402 PolarHBondContact N-O 2.85Å; G369-D402 VanDerWaalsContact N-O 3.14Å; D402-L404 WeakPolarHBondContact O-CD2 3.44Å; D402-L404 WeakPolarHBondContact O-CG 3.47Å; D402-L404 PolarHBondContact O-N 3.02Å; D402-K457 IonicContact OD1-NZ 2.76Å; D402-K457 PolarHBondContact OD1-NZ 3.45Å
403L94.9Very high91.4Very high3 Ų339 Ų392%0.01620%0.199CC..  trans-62.1120.8176.3-178.264.9000111.5L366 I400 G401 I406 V450 F461 K481L366-L403 HydrophobicContact CB-CD1 3.8Å; L366-L403 HydrophobicContact CD2-CD1 4.08Å; L366-L403 HydrophobicContact CG-CD1 4.37Å; I400-L403 HydrophobicContact CD1-CB 4.37Å; I400-L403 HydrophobicContact CD1-CD1 3.8Å; G401-L403 PolarHBondContact O-N 3.36Å; L403-I406 HydrophobicContact CD1-CG1 4.3Å; L403-I406 HydrophobicContact CD2-CD1 4.14Å; L403-I406 HydrophobicContact CD2-CG1 4.24Å; L403-V450 HydrophobicContact CD2-CB 4.48Å; L403-V450 HydrophobicContact CD2-CG1 4.05Å; L403-V450 HydrophobicContact CD2-CG2 4.38Å; L403-F461 HydrophobicContact CB-CZ 4.23Å; L403-F461 HydrophobicContact CD2-CE2 3.63Å; L403-F461 HydrophobicContact CD2-CZ 3.62Å; L403-F461 HydrophobicContact CG-CE1 4.27Å; L403-F461 HydrophobicContact CG-CE2 4.14Å; L403-F461 HydrophobicContact CG-CZ 3.57Å; L403-K481 WeakPolarHBondContact O-CE 3.44Å; L403-K481 PolarHBondContact O-NZ 3Å
404L93.6Very high89.6Confident83 Ų8343.7 Ų43.744%0.43523%0.233SC..  trans-106.4-41.2-175.2-57.5-174.2000113.3Y367 G368 D402 F461Y367-L404 PolarHBondContact O-N 3.28Å; G368-L404 WeakPolarHBondContact O-CD1 3.5Å; D402-L404 WeakPolarHBondContact O-CD2 3.44Å; D402-L404 WeakPolarHBondContact O-CG 3.47Å; D402-L404 PolarHBondContact O-N 3.02Å; L404-F461 WeakPolarHBondContact O-CE1 3.28Å
405K95.5Very high87.5Confident53 Ų5350 Ų5023%0.2326%0.263CS..EExtended strand (participates in β ladder)trans-149152.6-175.3162.1173.8157.3161.90111Y367 T478 F479 V480Y367-K405 HydrophobicContact CD2-CB 4.2Å; Y367-K405 HydrophobicContact CD2-CD 4.29Å; Y367-K405 HydrophobicContact CD2-CG 3.75Å; Y367-K405 HydrophobicContact CE2-CG 4.36Å; Y367-K405 HydrophobicContact CG-CB 4.29Å; Y367-K405 HydrophobicContact CG-CG 4.21Å; Y367-K405 PolarHBondContact N-O 3.11Å; Y367-K405 PolarHBondContact O-N 2.84Å; K405-T478 HydrophobicContact CD-CG2 3.41Å; K405-T478 VanDerWaalsContact CD-CG2 3.41Å; K405-T478 HydrophobicContact CG-CG2 3.66Å; K405-F479 WeakPolarHBondContact CA-O 3.29Å; K405-V480 HydrophobicContact CB-CG1 4.45Å; K405-V480 HydrophobicContact CD-CG1 4.41Å; K405-V480 HydrophobicContact CG-CG1 4.48Å
406I97.1Very high85.6Confident0 Ų050 Ų500%027%0.267CS..EExtended strand (participates in β ladder)trans-126.9126.4177.4-55.7173.9000107.4M345 V364 L366 L403 I448 V450 F461 T478 F479M345-I406 HydrophobicContact CE-CD1 4.2Å; V364-I406 HydrophobicContact CG1-CG2 3.75Å; L366-I406 HydrophobicContact CD2-CG1 4.23Å; L366-I406 HydrophobicContact CD2-CG2 4.3Å; L403-I406 HydrophobicContact CD1-CG1 4.3Å; L403-I406 HydrophobicContact CD2-CD1 4.14Å; L403-I406 HydrophobicContact CD2-CG1 4.24Å; I406-I448 HydrophobicContact CD1-CG2 4.27Å; I406-I448 HydrophobicContact CG2-CD1 4.23Å; I406-V450 HydrophobicContact CD1-CG2 3.64Å; I406-F461 HydrophobicContact CD1-CB 4.19Å; I406-F461 HydrophobicContact CD1-CD1 4.21Å; I406-F461 HydrophobicContact CD1-CD2 3.59Å; I406-F461 HydrophobicContact CD1-CE2 3.97Å; I406-F461 HydrophobicContact CD1-CG 3.74Å; I406-F461 HydrophobicContact CD1-CZ 4.48Å; I406-F461 HydrophobicContact CG1-CD1 4.24Å; I406-F461 HydrophobicContact CG1-CD2 4.43Å; I406-F461 HydrophobicContact CG1-CE1 4.46Å; I406-F461 HydrophobicContact CG1-CG 4.26Å; I406-T478 CarbonylContact O-C 3.45Å; I406-T478 WeakPolarHBondContact O-CA 3.43Å; I406-F479 HydrophobicContact CB-CB 4.42Å; I406-F479 PolarHBondContact N-O 3.07Å; I406-F479 PolarHBondContact O-N 3.32Å
407R97.3Very high83.6Confident94 Ų9457.1 Ų57.136%0.35530%0.304SS..EExtended strand (participates in β ladder)trans-102.1122.1164.8175.2179.1-91.1172.6-8108.1V364 K365 Y367 I477V364-R407 CarbonylContact C-O 3.6Å; V364-R407 WeakPolarHBondContact CA-O 3.33Å; K365-R407 HydrophobicContact CB-CB 4.35Å; K365-R407 PolarHBondContact N-O 3.43Å; K365-R407 PolarHBondContact O-N 3.3Å; Y367-R407 HydrophobicContact CE2-CB 3.8Å; R407-I477 WeakPolarHBondContact CA-O 3.04Å
408L96Very high81.7Confident0 Ų055.9 Ų55.90%031%0.305CS..EExtended strand (participates in β ladder)trans-102.3125.5171179.769000108.1M347 F362 Y363 V364 I445 S476 I477 F479M347-L408 HydrophobicContact CE-CD1 3.81Å; M347-L408 HydrophobicContact CE-CD2 3.78Å; M347-L408 HydrophobicContact CE-CG 4.46Å; M347-L408 HydrophobicContact SD-CD2 4Å; F362-L408 HydrophobicContact CB-CD1 3.9Å; F362-L408 HydrophobicContact CD1-CD1 3.99Å; F362-L408 HydrophobicContact CD1-CD2 4.46Å; F362-L408 HydrophobicContact CD1-CG 4.22Å; F362-L408 HydrophobicContact CG-CD1 4.02Å; Y363-L408 WeakPolarHBondContact O-CA 3.41Å; V364-L408 HydrophobicContact CG2-CD1 3.71Å; L408-I445 HydrophobicContact CD2-CD1 3.42Å; L408-I445 VanDerWaalsContact CD2-CD1 3.42Å; L408-S476 CarbonylContact O-C 3.5Å; L408-S476 WeakPolarHBondContact O-CA 3.49Å; L408-S476 WeakPolarHBondContact O-CB 3.3Å; L408-I477 PolarHBondContact N-O 2.63Å; L408-I477 PolarHBondContact O-N 3.49Å; L408-F479 HydrophobicContact CB-CD2 4.48Å; L408-F479 HydrophobicContact CB-CE2 3.93Å; L408-F479 HydrophobicContact CD2-CE2 4.31Å
409S94.4Very high79.8Confident24 Ų2453 Ų5317%0.16829%0.294CS..EExtended strand (participates in β ladder)trans-119.3145.4176.6-53.70000110F362 Y363 E475 S476F362-S409 WeakPolarHBondContact CA-O 3.4Å; Y363-S409 PolarHBondContact N-O 2.95Å; Y363-S409 PolarHBondContact O-N 2.96Å; S409-E475 WeakPolarHBondContact CA-O 3.32Å; S409-S476 WeakPolarHBondContact OG-CB 2.76Å
410W91.2Very high77.9Confident15 Ų1553.5 Ų53.56%0.05730%0.299CS..EExtended strand (participates in β ladder)trans-106.5123.8170.4-174-5.7000108.6F355 P360 F362 G412 P441 L443 I471 P473 G474 E475F355-W410 HydrophobicContact CD2-CH2 4.24Å; F355-W410 AromaticContact CE2-CH2 3.58Å; F355-W410 HydrophobicContact CE2-CH2 3.58Å; F355-W410 AromaticContact CE2-CZ2 3.78Å; F355-W410 HydrophobicContact CE2-CZ2 3.78Å; F355-W410 HydrophobicContact CZ-CZ2 4.47Å; P360-W410 HydrophobicContact CB-CD2 4.19Å; P360-W410 HydrophobicContact CB-CZ2 3.77Å; F362-W410 HydrophobicContact CD1-CB 4.2Å; F362-W410 HydrophobicContact CD1-CG 4.49Å; F362-W410 HydrophobicContact CE1-CB 4.11Å; F362-W410 HydrophobicContact CE1-CD2 4.43Å; F362-W410 HydrophobicContact CE1-CG 4.21Å; W410-G412 PolarHBondContact O-N 3.11Å; W410-P441 HydrophobicContact CH2-CB 3.82Å; W410-P441 HydrophobicContact CH2-CG 3.71Å; W410-P441 HydrophobicContact CZ2-CG 4.03Å; W410-L443 HydrophobicContact CE3-CD1 4.39Å; W410-L443 HydrophobicContact CH2-CD1 3.9Å; W410-L443 HydrophobicContact CH2-CG 4Å; W410-L443 HydrophobicContact CZ3-CB 4.33Å; W410-L443 HydrophobicContact CZ3-CD1 3.8Å; W410-L443 HydrophobicContact CZ3-CG 3.79Å; W410-I471 HydrophobicContact CB-CD1 3.91Å; W410-I471 HydrophobicContact CB-CG1 4.1Å; W410-I471 HydrophobicContact CE3-CG1 4.4Å; W410-I471 HydrophobicContact CE3-CG2 4.2Å; W410-I471 WeakPolarHBondContact CZ3-O 3.36Å; W410-P473 HydrophobicContact CD2-CB 4.46Å; W410-P473 HydrophobicContact CD2-CG 4.08Å; W410-P473 HydrophobicContact CE3-CG 4.33Å; W410-P473 HydrophobicContact CH2-CG 4.04Å; W410-P473 HydrophobicContact CZ2-CG 3.73Å; W410-P473 HydrophobicContact CZ3-CG 4.31Å; W410-G474 VanDerWaalsContact O-CA 3.31Å; W410-G474 WeakPolarHBondContact O-CA 3.42Å; W410-G474 PolarHBondContact O-N 3.42Å; W410-E475 PolarHBondContact N-O 2.92Å
411E87.4Confident75.9Confident20 Ų2061 Ų619%0.09333%0.332CS..  trans-47.7135.7173-164.7167.7-120.700112.4T361 Y363 E415T361-E411 WeakPolarHBondContact CB-OE2 3.38Å; T361-E411 HydrophobicContact CG2-CB 4.1Å; T361-E411 VanDerWaalsContact CG2-OE2 3.24Å; T361-E411 WeakPolarHBondContact CG2-OE2 3.48Å; T361-E411 PolarHBondContact O-N 2.9Å; T361-E411 PolarHBondContact OG1-OE2 2.85Å; Y363-E411 HydrophobicContact CE2-CB 3.9Å; Y363-E411 HydrophobicContact CE2-CG 4.13Å; Y363-E411 PolarHBondContact OH-OE1 3.25Å; E411-E415 HydrophobicContact CG-CB 4.42Å
412G80.3Confident74.1Confident8 Ų865 Ų658%0.08234%0.343CS..  trans-87.3163.6176.200000113.2W410 S414 E415W410-G412 PolarHBondContact O-N 3.11Å; G412-S414 PolarHBondContact O-N 2.73Å; G412-S414 VanDerWaalsContact O-N 3.11Å; G412-E415 PolarHBondContact O-N 2.82Å
413D65.9Low72.2Confident121 Ų12169.3 Ų69.365%0.64735%0.354SS*.THydrogen-bonded Turntrans-62.7-20.9-175.5-61.9-42.5000114.3S419D413-S419 PolarHBondContact O-OG 2.86Å
414S56.8Low70.1Confident116 Ų11672.9 Ų72.981%0.81137%0.373SS*.THydrogen-bonded Turntrans-1025.8-172.3580000115.8G412G412-S414 PolarHBondContact O-N 2.73Å; G412-S414 VanDerWaalsContact O-N 3.11Å
415E51.5Low68.2Low136 Ų13675.4 Ų75.464%0.63638%0.38SS*.SBendtrans-103.2-4-166.2-63.4-170.9156.100115.4E411 G412E411-E415 HydrophobicContact CG-CB 4.42Å; G412-E415 PolarHBondContact O-N 2.82Å
416S53.9Low66.1Low37 Ų3777.2 Ų77.226%0.25939%0.392SS..  trans-153.3146.4-175.4179.70000114.8S418 S419 V420S416-S418 PolarHBondContact O-N 3.31Å; S416-S418 PolarHBondContact OG-N 2.83Å; S416-S418 PolarHBondContact OG-OG 3.48Å; S416-S419 PolarHBondContact O-N 3.21Å; S416-S419 PolarHBondContact O-OG 3.28Å; S416-V420 PolarHBondContact O-N 3.23Å
417L50.5Low63.9Low156 Ų15680.6 Ų80.682%0.81742%0.416SS*.Hα-helixtrans-60.1-25.2170.7-77.5165.9000112.7F421L417-F421 PolarHBondContact O-N 3.3Å; L417-F421 VanDerWaalsContact O-N 3.11Å
418S51Low61.6Low58 Ų5884 Ų8441%0.40643%0.433SS..Hα-helixtrans-73-33.8-18070.50000113.3S416 F421 K422S416-S418 PolarHBondContact O-N 3.31Å; S416-S418 PolarHBondContact OG-N 2.83Å; S416-S418 PolarHBondContact OG-OG 3.48Å; S418-F421 PolarHBondContact O-N 3.04Å; S418-K422 WeakPolarHBondContact O-CG 3.13Å; S418-K422 PolarHBondContact O-N 2.95Å
419S50.6Low59.3Low22 Ų2294.2 Ų94.215%0.15447%0.472CS..Hα-helixtrans-72.9-35.1174.954.70000111.2D413 S416 K422 Y423D413-S419 PolarHBondContact O-OG 2.86Å; S416-S419 PolarHBondContact O-N 3.21Å; S416-S419 PolarHBondContact O-OG 3.28Å; S419-K422 PolarHBondContact O-N 3.38Å; S419-Y423 WeakPolarHBondContact O-CB 3.47Å; S419-Y423 PolarHBondContact O-N 2.94Å
420V50.7Low57Low74 Ų7498.8 Ų98.845%0.44850%0.495SS..Hα-helixtrans-60.8-45171179.10000111S416 Y423 I424S416-V420 PolarHBondContact O-N 3.23Å; V420-Y423 PolarHBondContact O-N 3.19Å; V420-I424 HydrophobicContact CG1-CD1 3.78Å; V420-I424 HydrophobicContact CG1-CG1 4.46Å; V420-I424 VanDerWaalsContact O-CG1 3.24Å; V420-I424 WeakPolarHBondContact O-CG1 3.45Å; V420-I424 PolarHBondContact O-N 3.35Å
421F51.6Low54.5Low158 Ų158108.9 Ų108.969%0.69353%0.533SS*.Hα-helixtrans-67.7-38.3178.4-144.4-92.1000112.7L417 S418 I424 K425L417-F421 PolarHBondContact O-N 3.3Å; L417-F421 VanDerWaalsContact O-N 3.11Å; S418-F421 PolarHBondContact O-N 3.04Å; F421-I424 PolarHBondContact O-N 2.91Å; F421-K425 WeakPolarHBondContact O-CB 3.33Å; F421-K425 PolarHBondContact O-N 3.46Å
422K54.7Low52.5Low107 Ų107115.8 Ų115.847%0.46557%0.571SS.*Hα-helixtrans-62.4-42.4172.2-77.8178.9177.4178.60111.8S418 S419 K425 N426S418-K422 WeakPolarHBondContact O-CG 3.13Å; S418-K422 PolarHBondContact O-N 2.95Å; S419-K422 PolarHBondContact O-N 3.38Å; K422-K425 PolarHBondContact O-N 2.93Å; K422-N426 PolarHBondContact O-N 2.86Å; K422-N426 VanDerWaalsContact O-N 3.07Å
423Y51.6Low50.7Low171 Ų171118.6 Ų118.667%0.67159%0.593SS**Hα-helixtrans-65-45.1176.8-175.2-93.2000112S419 V420 K425 N426 S427S419-Y423 WeakPolarHBondContact O-CB 3.47Å; S419-Y423 PolarHBondContact O-N 2.94Å; V420-Y423 PolarHBondContact O-N 3.19Å; Y423-K425 PolarHBondContact O-N 2.95Å; Y423-N426 PolarHBondContact O-N 3.5Å; Y423-S427 WeakPolarHBondContact O-CB 3.38Å; Y423-S427 PolarHBondContact O-N 3.23Å
424I51.2Low50Low78 Ų78123.7 Ų123.740%0.461%0.609SS.*Hα-helixtrans-62.2-42.4177.2-69166.5000111.1V420 F421 S427 F428V420-I424 HydrophobicContact CG1-CD1 3.78Å; V420-I424 HydrophobicContact CG1-CG1 4.46Å; V420-I424 VanDerWaalsContact O-CG1 3.24Å; V420-I424 WeakPolarHBondContact O-CG1 3.45Å; V420-I424 PolarHBondContact O-N 3.35Å; F421-I424 PolarHBondContact O-N 2.91Å; I424-S427 PolarHBondContact O-N 3.16Å; I424-F428 HydrophobicContact CG2-CD2 4.1Å; I424-F428 HydrophobicContact CG2-CE2 4.46Å; I424-F428 PolarHBondContact O-N 3.49Å
425K52.3Low49.4Very low136 Ų136122 Ų12259%0.59160%0.602SS**Hα-helixtrans-60.8-49.1176.2-167.6176.8-178.8-179.80110.9F421 K422 Y423 S427 F428 W429F421-K425 WeakPolarHBondContact O-CB 3.33Å; F421-K425 PolarHBondContact O-N 3.46Å; K422-K425 PolarHBondContact O-N 2.93Å; Y423-K425 PolarHBondContact O-N 2.95Å; K425-S427 VanDerWaalsContact C-N 3.26Å; K425-S427 PolarHBondContact O-N 2.72Å; K425-F428 PolarHBondContact O-N 2.93Å; K425-W429 VanDerWaalsContact O-CD1 3.25Å
426N52.7Low49.3Very low91 Ų91119.8 Ų119.849%0.48761%0.607SS.*Hα-helixtrans-63.9-30.9176.5-81.9-1.6000113.1K422 Y423K422-N426 PolarHBondContact O-N 2.86Å; K422-N426 VanDerWaalsContact O-N 3.07Å; Y423-N426 PolarHBondContact O-N 3.5Å
427S50.3Low49Very low70 Ų70127.8 Ų127.849%0.4964%0.637SS.*Hα-helixtrans-74.7-27.7177.6-1530000113.2Y423 I424 K425Y423-S427 WeakPolarHBondContact O-CB 3.38Å; Y423-S427 PolarHBondContact O-N 3.23Å; I424-S427 PolarHBondContact O-N 3.16Å; K425-S427 VanDerWaalsContact C-N 3.26Å; K425-S427 PolarHBondContact O-N 2.72Å
428F48.3Very low49.3Very low165 Ų165125.9 Ų125.972%0.72463%0.634SS**Hα-helixtrans-73.2-29.8177.9-113.2-90.4000113.6I424 K425I424-F428 HydrophobicContact CG2-CD2 4.1Å; I424-F428 HydrophobicContact CG2-CE2 4.46Å; I424-F428 PolarHBondContact O-N 3.49Å; K425-F428 PolarHBondContact O-N 2.93Å
429W47.7Very low50Low215 Ų215127.1 Ų127.181%0.81465%0.648SS**SBendtrans-84.4-9.8178.2-71.991.7000113.9K425K425-W429 VanDerWaalsContact O-CD1 3.25Å
430N46Very low50.9Low121 Ų121132.7 Ų132.765%0.64767%0.669SS**  trans-113.837.5-173.7-100.30.3000113.4N432N430-N432 PolarHBondContact O-N 2.9Å
431W40.3Very low52.4Low226 Ų226130.5 Ų130.586%0.85666%0.657SS**  trans-77.424-177.7-156-1.4000115
432N44.7Very low54Low166 Ų166123.6 Ų123.689%0.88863%0.628SS**SBendtrans-151.967.7168.2-88.9-37.4000111.3N430N430-N432 PolarHBondContact O-N 2.9Å
433A43.6Very low55.6Low66 Ų66118.5 Ų118.555%0.54561%0.605SS.*  trans-153.6121.7156.900000110.1A435A433-A435 HydrophobicContact CB-CB 4.04Å; A433-A435 PolarHBondContact O-N 3.07Å
434K49.2Very low57.5Low228 Ų228110.7 Ų110.799%0.99158%0.575SS**  trans-65.284.6155.7-75.1179.8177.1176.90107
435A44.1Very low59.4Low80 Ų80107 Ų10766%0.66156%0.556SS**  trans-109.4131.3-174.100000111.1A433A433-A435 HydrophobicContact CB-CB 4.04Å; A433-A435 PolarHBondContact O-N 3.07Å
436A50.2Low61.2Low90 Ų90106.3 Ų106.374%0.74455%0.55SS*.PPolyproline II helixtrans-49.7154170.200000111.6P438A436-P438 VanDerWaalsContact O-N 3.11Å
437K48.7Very low63.1Low206 Ų206107 Ų10790%0.89655%0.545SS*.PPolyproline II helixtrans-46.4122.6173.5-77.6-176.9177.6179.80109A439K437-A439 PolarHBondContact O-N 3.39Å
438P56.9Low65.3Low116 Ų116103.6 Ų103.675%0.75352%0.522SS*.PPolyproline II helixtrans-58.6134.6-179.622-30.6000109.1A436 K440A436-P438 VanDerWaalsContact O-N 3.11Å; P438-K440 PolarHBondContact O-N 2.87Å
439A64.2Low67.5Low83 Ų83102.6 Ų102.669%0.68651%0.513SS*.PPolyproline II helixtrans-58.6136.2176.800000109.1K437K437-A439 PolarHBondContact O-N 3.39Å
440K70.9Confident69.8Low140 Ų14092.6 Ų92.661%0.60948%0.476SS*.PPolyproline II helixtrans-60.2130.4177.1-73.7-169.9175.9-1690109P438P438-K440 PolarHBondContact O-N 2.87Å
441P80.8Confident72.2Confident28 Ų2887.9 Ų87.918%0.18245%0.45CS..PPolyproline II helixtrans-64.9138.9178.124.8-31.6000110.3F355 W410 P473F355-P441 HydrophobicContact CD2-CB 3.48Å; F355-P441 VanDerWaalsContact CD2-CB 3.48Å; F355-P441 HydrophobicContact CD2-CG 4.47Å; F355-P441 HydrophobicContact CE2-CB 3.93Å; W410-P441 HydrophobicContact CH2-CB 3.82Å; W410-P441 HydrophobicContact CH2-CG 3.71Å; W410-P441 HydrophobicContact CZ2-CG 4.03Å; P441-P473 HydrophobicContact CG-CG 3.81Å; P441-P473 WeakPolarHBondContact O-CD 3.33Å
442V85.9Confident74.8Confident13 Ų1377.3 Ų77.38%0.07941%0.41CS..EExtended strand (participates in β ladder)trans-126.4123.6179.3-176.50000109.9K353 E470K353-V442 HydrophobicContact CB-CB 4.28Å; K353-V442 HydrophobicContact CB-CG2 4.48Å; K353-V442 HydrophobicContact CD-CB 4.5Å; K353-V442 HydrophobicContact CD-CG2 4.22Å; V442-E470 HydrophobicContact CG1-CB 3.79Å; V442-E470 HydrophobicContact CG1-CG 4.07Å
443L88.5Confident77.2Confident0 Ų069.4 Ų69.40%037%0.368CS..EExtended strand (participates in β ladder)trans-110.2145.9174.9-61178.1000109.6V349 F355 P360 F362 L386 W410 E470 I471V349-L443 HydrophobicContact CG1-CB 4.17Å; V349-L443 HydrophobicContact CG1-CD1 4.02Å; V349-L443 HydrophobicContact CG1-CD2 3.89Å; V349-L443 HydrophobicContact CG1-CG 4.25Å; F355-L443 HydrophobicContact CB-CD2 4.41Å; F355-L443 HydrophobicContact CD1-CD2 4.36Å; F355-L443 HydrophobicContact CD2-CD2 3.97Å; F355-L443 HydrophobicContact CD2-CG 4.44Å; F355-L443 HydrophobicContact CE2-CD1 4.28Å; F355-L443 HydrophobicContact CE2-CD2 4.25Å; F355-L443 HydrophobicContact CE2-CG 4.4Å; F355-L443 HydrophobicContact CG-CD2 4.01Å; F355-L443 HydrophobicContact CZ-CD1 4.34Å; P360-L443 HydrophobicContact CB-CD1 4.34Å; P360-L443 HydrophobicContact CG-CD1 4.12Å; F362-L443 HydrophobicContact CZ-CD1 3.95Å; L386-L443 HydrophobicContact CD2-CD2 3.82Å; W410-L443 HydrophobicContact CE3-CD1 4.39Å; W410-L443 HydrophobicContact CH2-CD1 3.9Å; W410-L443 HydrophobicContact CH2-CG 4Å; W410-L443 HydrophobicContact CZ3-CB 4.33Å; W410-L443 HydrophobicContact CZ3-CD1 3.8Å; W410-L443 HydrophobicContact CZ3-CG 3.79Å; L443-E470 CarbonylContact O-C 3.59Å; L443-E470 VanDerWaalsContact O-CA 3.28Å; L443-E470 WeakPolarHBondContact O-CA 3.43Å; L443-I471 HydrophobicContact CB-CG2 4.04Å; L443-I471 PolarHBondContact N-O 2.95Å; L443-I471 PolarHBondContact O-N 2.58Å
444E90.9Very high79.5Confident7 Ų768.4 Ų68.43%0.03335%0.352CS..EExtended strand (participates in β ladder)trans-112127.9173.8175.3-173.5-176.200110.6F350 R352 R446 T469 E470F350-E444 HydrophobicContact CB-CB 4.08Å; F350-E444 HydrophobicContact CD2-CG 4.38Å; F350-E444 WeakPolarHBondContact CD2-O 3.42Å; F350-E444 PolarHBondContact N-O 2.8Å; F350-E444 PolarHBondContact O-N 3.27Å; R352-E444 HydrophobicContact CG-CB 3.96Å; R352-E444 IonicContact CZ-OE2 3.51Å; R352-E444 VanDerWaalsContact CZ-OE2 3.26Å; R352-E444 IonicContact NE-OE2 3.94Å; R352-E444 PolarHBondContact NE-OE2 3.36Å; R352-E444 IonicContact NH2-OE1 2.69Å; R352-E444 IonicContact NH2-OE2 3.62Å; R352-E444 PolarHBondContact NH2-OE2 3.03Å; E444-R446 HydrophobicContact CG-CG 4.3Å; E444-R446 IonicContact OE1-CZ 2.98Å; E444-R446 IonicContact OE1-NE 2.85Å; E444-R446 PolarHBondContact OE1-NE 3.31Å; E444-R446 IonicContact OE1-NH2 2.74Å; E444-R446 PolarHBondContact OE1-NH2 3.42Å; E444-R446 IonicContact OE2-NH2 3.83Å; E444-R446 PolarHBondContact OE2-NH2 3Å; E444-T469 CarbonylContact C-O 3.51Å; E444-T469 VanDerWaalsContact CA-O 3.31Å; E444-T469 WeakPolarHBondContact CA-O 3.21Å; E444-T469 PolarHBondContact OE1-OG1 3.42Å; E444-E470 HydrophobicContact CB-CG 4.26Å
445I92Very high81.6Confident0 Ų060.6 Ų60.60%033%0.326CS..  trans-132.3109.6179.1-56.8165.2000108.6M347 V349 F362 L408 I448 T469 I471 F479M347-I445 HydrophobicContact CB-CG2 4.08Å; M347-I445 HydrophobicContact SD-CD1 3.61Å; M347-I445 HydrophobicContact SD-CG1 4.3Å; M347-I445 HydrophobicContact SD-CG2 4.28Å; V349-I445 HydrophobicContact CG2-CD1 4.44Å; V349-I445 HydrophobicContact CG2-CG1 4.24Å; F362-I445 HydrophobicContact CZ-CD1 4.26Å; L408-I445 HydrophobicContact CD2-CD1 3.42Å; L408-I445 VanDerWaalsContact CD2-CD1 3.42Å; I445-I448 HydrophobicContact CG2-CG1 4.48Å; I445-T469 PolarHBondContact N-O 3.48Å; I445-I471 HydrophobicContact CD1-CG2 4.1Å; I445-F479 HydrophobicContact CB-CZ 4.18Å; I445-F479 HydrophobicContact CG2-CE1 4.09Å; I445-F479 HydrophobicContact CG2-CZ 3.7Å; I445-F479 WeakPolarHBondContact O-CE1 3.44Å
446R90.4Very high83.9Confident122 Ų12259.6 Ų59.646%0.4631%0.308SS..  trans-88.8-35.1-175.6-60.6-178.2-179.1165.56.8113.5F350 E444 A463 T469F350-R446 HydrophobicContact CE2-CG 4.22Å; E444-R446 HydrophobicContact CG-CG 4.3Å; E444-R446 IonicContact OE1-CZ 2.98Å; E444-R446 IonicContact OE1-NE 2.85Å; E444-R446 PolarHBondContact OE1-NE 3.31Å; E444-R446 IonicContact OE1-NH2 2.74Å; E444-R446 PolarHBondContact OE1-NH2 3.42Å; E444-R446 IonicContact OE2-NH2 3.83Å; E444-R446 PolarHBondContact OE2-NH2 3Å; R446-A463 PolarHBondContact O-N 2.85Å; R446-T469 HydrophobicContact CG-CG2 4.26Å
447R92.4Very high86Confident104 Ų10459.2 Ų59.239%0.39229%0.289SS..EExtended strand (participates in β ladder)trans-153.3141.8-166.8178.4179.7150.8177.82.4111.7F461R447-F461 CarbonylContact C-O 3.31Å; R447-F461 VanDerWaalsContact CA-O 3.24Å; R447-F461 WeakPolarHBondContact CA-O 3.42Å; R447-F461 WeakPolarHBondContact CG-O 3.45Å
448I95.2Very high88.1Confident0 Ų056.1 Ų56.10%028%0.276CS..EExtended strand (participates in β ladder)trans-116.7125.1172.4-55.9179.5000108.5M345 K346 M347 I406 I445 V450 F461 F479M345-I448 HydrophobicContact CB-CG2 4.34Å; M345-I448 HydrophobicContact SD-CG2 4.36Å; K346-I448 CarbonylContact O-C 3.58Å; K346-I448 WeakPolarHBondContact O-CA 3.42Å; M347-I448 HydrophobicContact CB-CG1 4.21Å; I406-I448 HydrophobicContact CD1-CG2 4.27Å; I406-I448 HydrophobicContact CG2-CD1 4.23Å; I445-I448 HydrophobicContact CG2-CG1 4.48Å; I448-V450 HydrophobicContact CG2-CG2 3.93Å; I448-F461 PolarHBondContact N-O 3.23Å; I448-F461 PolarHBondContact O-N 3.04Å; I448-F479 HydrophobicContact CD1-CD1 4.3Å; I448-F479 HydrophobicContact CD1-CD2 3.57Å; I448-F479 HydrophobicContact CD1-CE1 4.38Å; I448-F479 HydrophobicContact CD1-CE2 3.66Å; I448-F479 HydrophobicContact CD1-CG 3.93Å; I448-F479 HydrophobicContact CD1-CZ 4.08Å; I448-F479 HydrophobicContact CG1-CD1 4.13Å; I448-F479 HydrophobicContact CG1-CD2 4.29Å; I448-F479 HydrophobicContact CG1-CE1 4.15Å; I448-F479 HydrophobicContact CG1-CE2 4.3Å; I448-F479 HydrophobicContact CG1-CG 4.22Å; I448-F479 HydrophobicContact CG1-CZ 4.24Å
449R95.9Very high89.8Confident144 Ų14451.5 Ų51.554%0.54324%0.244SC..EExtended strand (participates in β ladder)trans-96.6129.8170.7-59178.1-174.6-170.1-5.1108.4M345 K346 F459M345-R449 CarbonylContact C-O 3.36Å; M345-R449 WeakPolarHBondContact CA-O 3.42Å; K346-R449 HydrophobicContact CB-CB 4.31Å; K346-R449 PolarHBondContact N-O 3.34Å; K346-R449 PolarHBondContact O-N 3Å; R449-F459 WeakPolarHBondContact CA-O 3.46Å
450V95.9Very high91.2Very high5 Ų548.9 Ų48.93%0.0322%0.223CC..EExtended strand (participates in β ladder)trans-118.9140.7-178.9-176.70000110.1Y343 Q344 M345 L403 I406 I448 K458 F459 F461Y343-V450 HydrophobicContact CD1-CG1 3.84Å; Y343-V450 HydrophobicContact CG-CG1 4.48Å; Q344-V450 CarbonylContact O-C 3.55Å; Q344-V450 VanDerWaalsContact O-CA 3.24Å; Q344-V450 WeakPolarHBondContact O-CA 3.46Å; M345-V450 HydrophobicContact CE-CG2 4.25Å; M345-V450 HydrophobicContact CG-CG2 4.11Å; M345-V450 HydrophobicContact SD-CG2 4.43Å; L403-V450 HydrophobicContact CD2-CB 4.48Å; L403-V450 HydrophobicContact CD2-CG1 4.05Å; L403-V450 HydrophobicContact CD2-CG2 4.38Å; I406-V450 HydrophobicContact CD1-CG2 3.64Å; I448-V450 HydrophobicContact CG2-CG2 3.93Å; V450-K458 CarbonylContact O-C 3.58Å; V450-K458 WeakPolarHBondContact O-CA 3.47Å; V450-F459 HydrophobicContact CB-CB 4.41Å; V450-F459 HydrophobicContact CB-CD2 4.42Å; V450-F459 HydrophobicContact CG1-CD2 4.48Å; V450-F459 PolarHBondContact N-O 2.8Å; V450-F459 PolarHBondContact O-N 2.98Å; V450-F461 HydrophobicContact CB-CD2 4.47Å; V450-F461 HydrophobicContact CB-CE2 4.25Å; V450-F461 HydrophobicContact CG2-CD2 3.89Å; V450-F461 HydrophobicContact CG2-CE2 4.01Å
451K95.8Very high92.4Very high22 Ų2242.2 Ų42.210%0.09619%0.194CC..EExtended strand (participates in β ladder)trans-125.1120.4164.5177.2-172.1173.7-170.60108.4L303 S304 Y343 Q344 K457 K458L303-K451 WeakPolarHBondContact O-CE 3.34Å; L303-K451 PolarHBondContact O-NZ 3.34Å; S304-K451 VanDerWaalsContact CA-NZ 3.34Å; Y343-K451 WeakPolarHBondContact CA-O 3.44Å; Q344-K451 HydrophobicContact CB-CB 4.23Å; Q344-K451 PolarHBondContact N-O 2.98Å; Q344-K451 PolarHBondContact O-N 2.84Å; K451-K457 WeakPolarHBondContact CA-O 3.41Å; K451-K458 HydrophobicContact CB-CG 4.15Å; K451-K458 HydrophobicContact CG-CG 4.03Å
452A95.3Very high93Very high3 Ų342.9 Ų42.93%0.02520%0.198CC..EExtended strand (participates in β ladder)trans-79.3131.6170.100000109.3Y343 S455 Q456 K457 F459Y343-A452 HydrophobicContact CD1-CB 3.93Å; Y343-A452 HydrophobicContact CE1-CB 3.73Å; A452-S455 VanDerWaalsContact CB-OG 3.27Å; A452-S455 WeakPolarHBondContact CB-OG 3.35Å; A452-Q456 CarbonylContact O-C 3.53Å; A452-Q456 WeakPolarHBondContact O-CA 3.3Å; A452-Q456 PolarHBondContact O-N 2.76Å; A452-Q456 VanDerWaalsContact O-N 3.15Å; A452-K457 PolarHBondContact N-O 3.11Å; A452-F459 HydrophobicContact CB-CE2 4.32Å
453G94.3Very high93.4Very high0 Ų042.8 Ų42.80%020%0.199CC..SBendtrans-70.3-54.317900000111.1Y289 H342 S455 Q456Y289-G453 WeakPolarHBondContact OH-CA 3.41Å; H342-G453 PolarHBondContact O-N 3.49Å; G453-S455 PolarHBondContact O-N 2.84Å; G453-Q456 PolarHBondContact O-N 3.48Å; G453-Q456 PolarHBondContact O-NE2 2.72Å
454E92.4Very high93.6Very high46 Ų4648.2 Ų48.222%0.21522%0.224CC..THydrogen-bonded Turntrans-66.7-45.4-170.3-67.462.2-13200110.9Y287 Y289 Y341 H342Y287-E454 HydrophobicContact CD2-CG 4.17Å; Y289-E454 PolarHBondContact OH-N 2.89Å; Y289-E454 PolarHBondContact OH-OE1 2.79Å; Y341-E454 WeakPolarHBondContact CA-OE2 3.19Å; Y341-E454 HydrophobicContact CD1-CB 4.34Å; Y341-E454 HydrophobicContact CD1-CG 4.02Å; H342-E454 IonicContact CE1-OE1 3.97Å; H342-E454 IonicContact CG-OE1 3.43Å; H342-E454 PolarHBondContact N-OE1 2.84Å; H342-E454 PolarHBondContact N-OE2 3.43Å; H342-E454 IonicContact ND1-OE1 3.77Å; H342-E454 PolarHBondContact ND1-OE1 3.24Å
455S92.3Very high93.5Very high63 Ų6350.8 Ų50.844%0.44124%0.238SC..THydrogen-bonded Turntrans-86-7.9178.166.70000114.4A452 G453 K457A452-S455 VanDerWaalsContact CB-OG 3.27Å; A452-S455 WeakPolarHBondContact CB-OG 3.35Å; G453-S455 PolarHBondContact O-N 2.84Å; S455-K457 PolarHBondContact O-N 2.87Å
456Q93.8Very high93.2Very high59 Ų5956 Ų5628%0.27627%0.272SS..  trans52.812.1-171.5-65.4-69.4-62.200115L303 C305 A452 G453L303-Q456 PolarHBondContact O-NE2 2.98Å; C305-Q456 HydrophobicContact CB-CG 4.05Å; C305-Q456 VanDerWaalsContact N-OE1 3.13Å; A452-Q456 CarbonylContact O-C 3.53Å; A452-Q456 WeakPolarHBondContact O-CA 3.3Å; A452-Q456 PolarHBondContact O-N 2.76Å; A452-Q456 VanDerWaalsContact O-N 3.15Å; G453-Q456 PolarHBondContact O-N 3.48Å; G453-Q456 PolarHBondContact O-NE2 2.72Å
457K92.9Very high93Very high82 Ų8254.7 Ų54.736%0.35728%0.282SS..  trans-72.8151.4178.7-66.5179.3-174.3178.30111D402 K451 A452 S455 F459D402-K457 IonicContact OD1-NZ 2.76Å; D402-K457 PolarHBondContact OD1-NZ 3.45Å; K451-K457 WeakPolarHBondContact CA-O 3.41Å; A452-K457 PolarHBondContact N-O 3.11Å; S455-K457 PolarHBondContact O-N 2.87Å; K457-F459 HydrophobicContact CB-CE1 4.2Å; K457-F459 HydrophobicContact CB-CE2 3.6Å; K457-F459 HydrophobicContact CB-CZ 3.4Å; K457-F459 HydrophobicContact CD-CE1 4.31Å; K457-F459 HydrophobicContact CD-CZ 3.7Å; K457-F459 HydrophobicContact CG-CZ 4.19Å
458K93.8Very high92.8Very high141 Ų14156.5 Ų56.561%0.61329%0.292SS*.EExtended strand (participates in β ladder)trans-125139.6176.3-69.3-179.9175.1179.50110.1V450 K451V450-K458 CarbonylContact O-C 3.58Å; V450-K458 WeakPolarHBondContact O-CA 3.47Å; K451-K458 HydrophobicContact CB-CG 4.15Å; K451-K458 HydrophobicContact CG-CG 4.03Å
459F91.8Very high92.6Very high19 Ų1957.5 Ų57.58%0.08330%0.299CS..EExtended strand (participates in β ladder)trans-136.4156.6-174.6-49.1-83.7000110.8R449 V450 A452 K457 F461 W486R449-F459 WeakPolarHBondContact CA-O 3.46Å; V450-F459 HydrophobicContact CB-CB 4.41Å; V450-F459 HydrophobicContact CB-CD2 4.42Å; V450-F459 HydrophobicContact CG1-CD2 4.48Å; V450-F459 PolarHBondContact N-O 2.8Å; V450-F459 PolarHBondContact O-N 2.98Å; A452-F459 HydrophobicContact CB-CE2 4.32Å; K457-F459 HydrophobicContact CB-CE1 4.2Å; K457-F459 HydrophobicContact CB-CE2 3.6Å; K457-F459 HydrophobicContact CB-CZ 3.4Å; K457-F459 HydrophobicContact CD-CE1 4.31Å; K457-F459 HydrophobicContact CD-CZ 3.7Å; K457-F459 HydrophobicContact CG-CZ 4.19Å; F459-F461 HydrophobicContact CB-CD2 4.08Å; F459-F461 HydrophobicContact CB-CE2 3.43Å; F459-F461 VanDerWaalsContact CB-CE2 3.43Å; F459-F461 HydrophobicContact CB-CZ 4.16Å; F459-F461 HydrophobicContact CG-CE2 4.14Å; F459-W486 HydrophobicContact CD1-CH2 4.14Å; F459-W486 AromaticContact CD1-CZ2 3.63Å; F459-W486 HydrophobicContact CD1-CZ2 3.63Å; F459-W486 AromaticContact CE1-CH2 3.72Å; F459-W486 HydrophobicContact CE1-CH2 3.72Å; F459-W486 AromaticContact CE1-CZ2 3.54Å; F459-W486 HydrophobicContact CE1-CZ2 3.54Å
460A94.5Very high92.4Very high29 Ų2954.3 Ų54.324%0.2429%0.29CS..EExtended strand (participates in β ladder)trans-125.9128.1167.300000108.7C482A460-C482 VanDerWaalsContact C-SG 3.51Å; A460-C482 PolarHBondContact O-N 3.46Å; A460-C482 PolarHBondContact O-SG 3.02Å; A460-C482 VanDerWaalsContact O-SG 3.37Å
461F95.1Very high92.1Very high0 Ų054.1 Ų54.10%029%0.289CS..EExtended strand (participates in β ladder)trans-114.8130177.5-66.6-96.6000109.3L403 L404 I406 R447 I448 V450 F459 F479 V480 K481L403-F461 HydrophobicContact CB-CZ 4.23Å; L403-F461 HydrophobicContact CD2-CE2 3.63Å; L403-F461 HydrophobicContact CD2-CZ 3.62Å; L403-F461 HydrophobicContact CG-CE1 4.27Å; L403-F461 HydrophobicContact CG-CE2 4.14Å; L403-F461 HydrophobicContact CG-CZ 3.57Å; L404-F461 WeakPolarHBondContact O-CE1 3.28Å; I406-F461 HydrophobicContact CD1-CB 4.19Å; I406-F461 HydrophobicContact CD1-CD1 4.21Å; I406-F461 HydrophobicContact CD1-CD2 3.59Å; I406-F461 HydrophobicContact CD1-CE2 3.97Å; I406-F461 HydrophobicContact CD1-CG 3.74Å; I406-F461 HydrophobicContact CD1-CZ 4.48Å; I406-F461 HydrophobicContact CG1-CD1 4.24Å; I406-F461 HydrophobicContact CG1-CD2 4.43Å; I406-F461 HydrophobicContact CG1-CE1 4.46Å; I406-F461 HydrophobicContact CG1-CG 4.26Å; R447-F461 CarbonylContact C-O 3.31Å; R447-F461 VanDerWaalsContact CA-O 3.24Å; R447-F461 WeakPolarHBondContact CA-O 3.42Å; R447-F461 WeakPolarHBondContact CG-O 3.45Å; I448-F461 PolarHBondContact N-O 3.23Å; I448-F461 PolarHBondContact O-N 3.04Å; V450-F461 HydrophobicContact CB-CD2 4.47Å; V450-F461 HydrophobicContact CB-CE2 4.25Å; V450-F461 HydrophobicContact CG2-CD2 3.89Å; V450-F461 HydrophobicContact CG2-CE2 4.01Å; F459-F461 HydrophobicContact CB-CD2 4.08Å; F459-F461 HydrophobicContact CB-CE2 3.43Å; F459-F461 VanDerWaalsContact CB-CE2 3.43Å; F459-F461 HydrophobicContact CB-CZ 4.16Å; F459-F461 HydrophobicContact CG-CE2 4.14Å; F461-F479 HydrophobicContact CB-CB 3.74Å; F461-V480 CarbonylContact C-O 3.57Å; F461-V480 WeakPolarHBondContact CA-O 3.35Å; F461-V480 VanDerWaalsContact CD1-C 3.47Å; F461-K481 HydrophobicContact CD1-CG 4.26Å; F461-K481 HydrophobicContact CE1-CG 3.68Å; F461-K481 HydrophobicContact CZ-CG 4.1Å
462C94.6Very high91.8Very high41 Ų4153.8 Ų53.828%0.27729%0.289SS..EExtended strand (participates in β ladder)trans-112.8151.1-178.5-70.20000108.7Q464 F479 V480 C482C462-Q464 PolarHBondContact O-N 2.8Å; C462-F479 CarbonylContact O-C 3.42Å; C462-F479 WeakPolarHBondContact O-CA 3.31Å; C462-V480 PolarHBondContact N-O 3.39Å; C462-V480 PolarHBondContact O-N 3.48Å; C462-C482 HydrophobicContact CB-CB 4.05Å; C462-C482 WeakPolarHBondContact CB-SG 3.31Å; C462-C482 PolarHBondContact N-SG 3.22Å; C462-C482 WeakPolarHBondContact SG-CB 3.24Å; C462-C482 CovalentContact SG-SG 2.05Å; C462-C482 PolarHBondContact SG-SG 2.93Å
463A93.8Very high91.5Very high12 Ų1254.2 Ų54.210%0.09929%0.292CS..EExtended strand (participates in β ladder)trans-52.213217700000110.2R446 D465 T469 I477 F479R446-A463 PolarHBondContact O-N 2.85Å; A463-D465 PolarHBondContact O-N 3.19Å; A463-T469 HydrophobicContact CB-CG2 3.87Å; A463-I477 HydrophobicContact CB-CG2 4.35Å; A463-F479 HydrophobicContact CB-CD1 4.4Å; A463-F479 HydrophobicContact CB-CE1 4.29Å
464Q92.4Very high91.2Very high113 Ų11356.9 Ų56.953%0.52832%0.319SS..SBendtrans-60.9-38.2-177.8-179.2177.3-4.500111.4C462 T478 V480C462-Q464 PolarHBondContact O-N 2.8Å; Q464-T478 HydrophobicContact CB-CG2 4Å; Q464-T478 PolarHBondContact N-O 2.89Å; Q464-V480 HydrophobicContact CB-CG1 4.17Å; Q464-V480 HydrophobicContact CB-CG2 4.29Å; Q464-V480 HydrophobicContact CG-CG1 4.2Å; Q464-V480 HydrophobicContact CG-CG2 4.49Å
465D90Very high91.2Very high61 Ų6159.2 Ų59.233%0.32633%0.33SS..SBendtrans-109.3110.8170.5-179.7-9.8000108A463 S467 K468A463-D465 PolarHBondContact O-N 3.19Å; D465-S467 VanDerWaalsContact CG-OG 3.22Å; D465-S467 PolarHBondContact O-N 3.48Å; D465-S467 VanDerWaalsContact O-N 3.11Å; D465-S467 WeakPolarHBondContact OD1-CB 3.31Å; D465-S467 PolarHBondContact OD1-N 3.32Å; D465-S467 PolarHBondContact OD1-OG 3.04Å; D465-S467 PolarHBondContact OD2-OG 3.46Å; D465-K468 HydrophobicContact CB-CB 4.11Å; D465-K468 HydrophobicContact CB-CD 4.29Å; D465-K468 HydrophobicContact CB-CG 4.26Å; D465-K468 PolarHBondContact O-N 3.11Å; D465-K468 VanDerWaalsContact OD2-CD 3.32Å; D465-K468 WeakPolarHBondContact OD2-CD 3.14Å; D465-K468 VanDerWaalsContact OD2-CE 3.3Å; D465-K468 WeakPolarHBondContact OD2-CE 3.44Å; D465-K468 WeakPolarHBondContact OD2-CG 3.24Å
466P85.1Confident91.3Very high110 Ų11058.9 Ų58.971%0.71433%0.327SS*.THydrogen-bonded Turntrans-60-19.6-179.9-24.434.3000114.3
467S85.9Confident91.4Very high95 Ų9556.5 Ų56.566%0.66432%0.317SS*.THydrogen-bonded Turntrans-82.3-15.3175.572.60000113.2D465D465-S467 VanDerWaalsContact CG-OG 3.22Å; D465-S467 PolarHBondContact O-N 3.48Å; D465-S467 VanDerWaalsContact O-N 3.11Å; D465-S467 WeakPolarHBondContact OD1-CB 3.31Å; D465-S467 PolarHBondContact OD1-N 3.32Å; D465-S467 PolarHBondContact OD1-OG 3.04Å; D465-S467 PolarHBondContact OD2-OG 3.46Å
468K88.7Confident91.6Very high141 Ų14153.7 Ų53.761%0.61331%0.306SS*.  trans-112.571.9-178.1-63.6-177.5-175179.80111.2D465D465-K468 HydrophobicContact CB-CB 4.11Å; D465-K468 HydrophobicContact CB-CD 4.29Å; D465-K468 HydrophobicContact CB-CG 4.26Å; D465-K468 PolarHBondContact O-N 3.11Å; D465-K468 VanDerWaalsContact OD2-CD 3.32Å; D465-K468 WeakPolarHBondContact OD2-CD 3.14Å; D465-K468 VanDerWaalsContact OD2-CE 3.3Å; D465-K468 WeakPolarHBondContact OD2-CE 3.44Å; D465-K468 WeakPolarHBondContact OD2-CG 3.24Å
469T90.1Very high91.7Very high21 Ų2147 Ų4713%0.12928%0.277CS..  trans-106-5.817554.50000113.1E444 I445 R446 A463 I477E444-T469 CarbonylContact C-O 3.51Å; E444-T469 VanDerWaalsContact CA-O 3.31Å; E444-T469 WeakPolarHBondContact CA-O 3.21Å; E444-T469 PolarHBondContact OE1-OG1 3.42Å; I445-T469 PolarHBondContact N-O 3.48Å; R446-T469 HydrophobicContact CG-CG2 4.26Å; A463-T469 HydrophobicContact CB-CG2 3.87Å; T469-I477 WeakPolarHBondContact O-CD1 3.23Å
470E91.4Very high91.9Very high78 Ų7848.3 Ų48.336%0.36429%0.287SS..EExtended strand (participates in β ladder)trans-91.3141177.3-65.9-175.7176.800110.6R352 V442 L443 E444R352-E470 IonicContact NE-OE1 3.65Å; V442-E470 HydrophobicContact CG1-CB 3.79Å; V442-E470 HydrophobicContact CG1-CG 4.07Å; L443-E470 CarbonylContact O-C 3.59Å; L443-E470 VanDerWaalsContact O-CA 3.28Å; L443-E470 WeakPolarHBondContact O-CA 3.43Å; E444-E470 HydrophobicContact CB-CG 4.26Å
471I90.5Very high91.8Very high0 Ų050.5 Ų50.50%029%0.291CS..EExtended strand (participates in β ladder)trans-132.7136.6177.2-167.7169.6000109.9W410 L443 I445 E475 I477W410-I471 HydrophobicContact CB-CD1 3.91Å; W410-I471 HydrophobicContact CB-CG1 4.1Å; W410-I471 HydrophobicContact CE3-CG1 4.4Å; W410-I471 HydrophobicContact CE3-CG2 4.2Å; W410-I471 WeakPolarHBondContact CZ3-O 3.36Å; L443-I471 HydrophobicContact CB-CG2 4.04Å; L443-I471 PolarHBondContact N-O 2.95Å; L443-I471 PolarHBondContact O-N 2.58Å; I445-I471 HydrophobicContact CD1-CG2 4.1Å; I471-E475 HydrophobicContact CG1-CB 4.12Å; I471-I477 HydrophobicContact CB-CD1 3.72Å; I471-I477 HydrophobicContact CB-CG1 4.04Å; I471-I477 HydrophobicContact CD1-CG1 4.36Å; I471-I477 HydrophobicContact CG1-CG1 4.42Å; I471-I477 HydrophobicContact CG2-CD1 4.32Å
472S89.4Confident91.5Very high16 Ų1651.7 Ų51.711%0.11230%0.299CS..  trans-120.1166.5173.6-37.70000110.6G474 E475S472-G474 PolarHBondContact O-N 3.11Å; S472-E475 VanDerWaalsContact CB-OE2 3.23Å; S472-E475 WeakPolarHBondContact CB-OE2 2.89Å; S472-E475 PolarHBondContact N-OE2 3.21Å; S472-E475 VanDerWaalsContact O-CB 3.31Å; S472-E475 WeakPolarHBondContact O-CB 3.46Å; S472-E475 PolarHBondContact O-N 3.43Å; S472-E475 PolarHBondContact OG-OE2 3.38Å
473P88.5Confident90.5Very high12 Ų1261.5 Ų61.58%0.07833%0.33CS..THydrogen-bonded Turntrans-54.2130.9174.4-25.633.5000112.3W410 P441 E475W410-P473 HydrophobicContact CD2-CB 4.46Å; W410-P473 HydrophobicContact CD2-CG 4.08Å; W410-P473 HydrophobicContact CE3-CG 4.33Å; W410-P473 HydrophobicContact CH2-CG 4.04Å; W410-P473 HydrophobicContact CZ2-CG 3.73Å; W410-P473 HydrophobicContact CZ3-CG 4.31Å; P441-P473 HydrophobicContact CG-CG 3.81Å; P441-P473 WeakPolarHBondContact O-CD 3.33Å; P473-E475 VanDerWaalsContact C-N 3.33Å
474G88.5Confident88.9Confident55 Ų5567.9 Ų67.957%0.56736%0.363SS*.THydrogen-bonded Turntrans84.6-3.4-175.400000115.1W410 S472W410-G474 VanDerWaalsContact O-CA 3.31Å; W410-G474 WeakPolarHBondContact O-CA 3.42Å; W410-G474 PolarHBondContact O-N 3.42Å; S472-G474 PolarHBondContact O-N 3.11Å
475E92.1Very high86.7Confident95 Ų9565.6 Ų65.644%0.44437%0.369SS..  trans-97.9166.5179.5-60.5-176.2148.100112.5S409 W410 I471 S472 P473S409-E475 WeakPolarHBondContact CA-O 3.32Å; W410-E475 PolarHBondContact N-O 2.92Å; I471-E475 HydrophobicContact CG1-CB 4.12Å; S472-E475 VanDerWaalsContact CB-OE2 3.23Å; S472-E475 WeakPolarHBondContact CB-OE2 2.89Å; S472-E475 PolarHBondContact N-OE2 3.21Å; S472-E475 VanDerWaalsContact O-CB 3.31Å; S472-E475 WeakPolarHBondContact O-CB 3.46Å; S472-E475 PolarHBondContact O-N 3.43Å; S472-E475 PolarHBondContact OG-OE2 3.38Å; P473-E475 VanDerWaalsContact C-N 3.33Å
476S94.8Very high84.7Confident56 Ų5670.2 Ų70.239%0.39238%0.382SS..EExtended strand (participates in β ladder)trans-139.9142.5173.669.30000112.4L408 S409L408-S476 CarbonylContact O-C 3.5Å; L408-S476 WeakPolarHBondContact O-CA 3.49Å; L408-S476 WeakPolarHBondContact O-CB 3.3Å; S409-S476 WeakPolarHBondContact OG-CB 2.76Å
477I95.8Very high82.4Confident10 Ų1073.9 Ų73.95%0.05139%0.39CS..EExtended strand (participates in β ladder)trans-109.8137.6172.1-58.3174.9000108.8R407 L408 A463 T469 I471 F479R407-I477 WeakPolarHBondContact CA-O 3.04Å; L408-I477 PolarHBondContact N-O 2.63Å; L408-I477 PolarHBondContact O-N 3.49Å; A463-I477 HydrophobicContact CB-CG2 4.35Å; T469-I477 WeakPolarHBondContact O-CD1 3.23Å; I471-I477 HydrophobicContact CB-CD1 3.72Å; I471-I477 HydrophobicContact CB-CG1 4.04Å; I471-I477 HydrophobicContact CD1-CG1 4.36Å; I471-I477 HydrophobicContact CG1-CG1 4.42Å; I471-I477 HydrophobicContact CG2-CD1 4.32Å; I477-F479 HydrophobicContact CB-CE2 3.72Å; I477-F479 HydrophobicContact CB-CZ 4.04Å; I477-F479 HydrophobicContact CD1-CZ 4.46Å; I477-F479 HydrophobicContact CG2-CD2 4.07Å; I477-F479 HydrophobicContact CG2-CE1 4.17Å; I477-F479 HydrophobicContact CG2-CE2 3.48Å; I477-F479 VanDerWaalsContact CG2-CE2 3.48Å; I477-F479 HydrophobicContact CG2-CZ 3.53Å
478T96.8Very high80.4Confident22 Ų2274.6 Ų74.614%0.13539%0.39CS..EExtended strand (participates in β ladder)trans-98.5134.1169.4-68.40000111K405 I406 Q464 V480K405-T478 HydrophobicContact CD-CG2 3.41Å; K405-T478 VanDerWaalsContact CD-CG2 3.41Å; K405-T478 HydrophobicContact CG-CG2 3.66Å; I406-T478 CarbonylContact O-C 3.45Å; I406-T478 WeakPolarHBondContact O-CA 3.43Å; Q464-T478 HydrophobicContact CB-CG2 4Å; Q464-T478 PolarHBondContact N-O 2.89Å; T478-V480 HydrophobicContact CG2-CG1 4.41Å
479F96.4Very high77.8Confident0 Ų076.7 Ų76.70%040%0.399CS..EExtended strand (participates in β ladder)trans-116135172.4-55.7-99.8000111K405 I406 L408 I445 I448 F461 C462 A463 I477K405-F479 WeakPolarHBondContact CA-O 3.29Å; I406-F479 HydrophobicContact CB-CB 4.42Å; I406-F479 PolarHBondContact N-O 3.07Å; I406-F479 PolarHBondContact O-N 3.32Å; L408-F479 HydrophobicContact CB-CD2 4.48Å; L408-F479 HydrophobicContact CB-CE2 3.93Å; L408-F479 HydrophobicContact CD2-CE2 4.31Å; I445-F479 HydrophobicContact CB-CZ 4.18Å; I445-F479 HydrophobicContact CG2-CE1 4.09Å; I445-F479 HydrophobicContact CG2-CZ 3.7Å; I445-F479 WeakPolarHBondContact O-CE1 3.44Å; I448-F479 HydrophobicContact CD1-CD1 4.3Å; I448-F479 HydrophobicContact CD1-CD2 3.57Å; I448-F479 HydrophobicContact CD1-CE1 4.38Å; I448-F479 HydrophobicContact CD1-CE2 3.66Å; I448-F479 HydrophobicContact CD1-CG 3.93Å; I448-F479 HydrophobicContact CD1-CZ 4.08Å; I448-F479 HydrophobicContact CG1-CD1 4.13Å; I448-F479 HydrophobicContact CG1-CD2 4.29Å; I448-F479 HydrophobicContact CG1-CE1 4.15Å; I448-F479 HydrophobicContact CG1-CE2 4.3Å; I448-F479 HydrophobicContact CG1-CG 4.22Å; I448-F479 HydrophobicContact CG1-CZ 4.24Å; F461-F479 HydrophobicContact CB-CB 3.74Å; C462-F479 CarbonylContact O-C 3.42Å; C462-F479 WeakPolarHBondContact O-CA 3.31Å; A463-F479 HydrophobicContact CB-CD1 4.4Å; A463-F479 HydrophobicContact CB-CE1 4.29Å; I477-F479 HydrophobicContact CB-CE2 3.72Å; I477-F479 HydrophobicContact CB-CZ 4.04Å; I477-F479 HydrophobicContact CD1-CZ 4.46Å; I477-F479 HydrophobicContact CG2-CD2 4.07Å; I477-F479 HydrophobicContact CG2-CE1 4.17Å; I477-F479 HydrophobicContact CG2-CE2 3.48Å; I477-F479 VanDerWaalsContact CG2-CE2 3.48Å; I477-F479 HydrophobicContact CG2-CZ 3.53Å
480V95.1Very high75.2Confident48 Ų4881.4 Ų81.429%0.29143%0.43SS..EExtended strand (participates in β ladder)trans-119163.6175.2-64.10000109.6K405 F461 C462 Q464 T478 C482K405-V480 HydrophobicContact CB-CG1 4.45Å; K405-V480 HydrophobicContact CD-CG1 4.41Å; K405-V480 HydrophobicContact CG-CG1 4.48Å; F461-V480 CarbonylContact C-O 3.57Å; F461-V480 WeakPolarHBondContact CA-O 3.35Å; F461-V480 VanDerWaalsContact CD1-C 3.47Å; C462-V480 PolarHBondContact N-O 3.39Å; C462-V480 PolarHBondContact O-N 3.48Å; Q464-V480 HydrophobicContact CB-CG1 4.17Å; Q464-V480 HydrophobicContact CB-CG2 4.29Å; Q464-V480 HydrophobicContact CG-CG1 4.2Å; Q464-V480 HydrophobicContact CG-CG2 4.49Å; T478-V480 HydrophobicContact CG2-CG1 4.41Å; V480-C482 PolarHBondContact O-N 3.35Å
481K92.1Very high72.8Confident75 Ų7589.3 Ų89.333%0.32646%0.456SS..EExtended strand (participates in β ladder)trans-51.8129.6177-69.5178.9-178.2168.40110L403 F461L403-K481 WeakPolarHBondContact O-CE 3.44Å; L403-K481 PolarHBondContact O-NZ 3Å; F461-K481 HydrophobicContact CD1-CG 4.26Å; F461-K481 HydrophobicContact CE1-CG 3.68Å; F461-K481 HydrophobicContact CZ-CG 4.1Å
482C88.7Confident70.6Confident25 Ų2599.1 Ų99.117%0.16950%0.499CS..  trans-60.5144.5178.6-59.60000110.5A460 C462 V480 D484A460-C482 VanDerWaalsContact C-SG 3.51Å; A460-C482 PolarHBondContact O-N 3.46Å; A460-C482 PolarHBondContact O-SG 3.02Å; A460-C482 VanDerWaalsContact O-SG 3.37Å; C462-C482 HydrophobicContact CB-CB 4.05Å; C462-C482 WeakPolarHBondContact CB-SG 3.31Å; C462-C482 PolarHBondContact N-SG 3.22Å; C462-C482 WeakPolarHBondContact SG-CB 3.24Å; C462-C482 CovalentContact SG-SG 2.05Å; C462-C482 PolarHBondContact SG-SG 2.93Å; V480-C482 PolarHBondContact O-N 3.35Å; C482-D484 VanDerWaalsContact C-N 3.34Å
483R74.9Confident68.3Low247 Ų247109.9 Ų109.993%0.93254%0.537SS*.SBendtrans-72.7-26.8-179.8-66.5-177.3-179.5-179.80.1112.9G485R483-G485 PolarHBondContact O-N 2.88Å
484D60Low65.9Low146 Ų146117 Ų11778%0.78157%0.574SS**SBendtrans-74.9118177.6-50.2-31.2000109.3C482C482-D484 VanDerWaalsContact C-N 3.34Å
485G46.3Very low64.2Low65 Ų65120.1 Ų120.167%0.6758%0.584SS**  trans-58.2164.5-156.300000117.6R483 E487R483-G485 PolarHBondContact O-N 2.88Å; G485-E487 PolarHBondContact O-N 3.34Å
486W47.8Very low61.9Low158 Ų158128.2 Ų128.260%0.59863%0.625SS**  trans-6290.3167-79.150.1000110.6F459 V488F459-W486 HydrophobicContact CD1-CH2 4.14Å; F459-W486 AromaticContact CD1-CZ2 3.63Å; F459-W486 HydrophobicContact CD1-CZ2 3.63Å; F459-W486 AromaticContact CE1-CH2 3.72Å; F459-W486 HydrophobicContact CE1-CH2 3.72Å; F459-W486 AromaticContact CE1-CZ2 3.54Å; F459-W486 HydrophobicContact CE1-CZ2 3.54Å; W486-V488 HydrophobicContact CE3-CG2 4.17Å; W486-V488 PolarHBondContact O-N 3.32Å
487E37.5Very low60.2Low186 Ų186131.8 Ų131.887%0.86964%0.637SS**  trans-72.385.4157.1-79.8-164.816900109G485 K489G485-E487 PolarHBondContact O-N 3.34Å; E487-K489 VanDerWaalsContact C-N 3.35Å; E487-K489 PolarHBondContact O-N 3.47Å
488V43.8Very low58.3Low110 Ų110138.2 Ų138.267%0.66767%0.668SS**  trans-60.2104.7153.2-176.50000105.3W486 P490W486-V488 HydrophobicContact CE3-CG2 4.17Å; W486-V488 PolarHBondContact O-N 3.32Å; V488-P490 WeakPolarHBondContact O-CD 3.34Å; V488-P490 VanDerWaalsContact O-N 3.07Å
489K33.8Very low56.2Low185 Ų185144.7 Ų144.780%0.80470%0.697SS**PPolyproline II helixtrans-46.1122.5173.9-74.6-168.1174.5-164.90108.5E487 R491E487-K489 VanDerWaalsContact C-N 3.35Å; E487-K489 PolarHBondContact O-N 3.47Å; K489-R491 PolarHBondContact O-N 2.97Å
490P35.8Very low53.8Low120 Ų120153.2 Ų153.278%0.77974%0.738SS**PPolyproline II helixtrans-57.7133-179.819-28.9000109.3V488 K492V488-P490 WeakPolarHBondContact O-CD 3.34Å; V488-P490 VanDerWaalsContact O-N 3.07Å; P490-K492 PolarHBondContact O-N 3.24Å; P490-K492 VanDerWaalsContact O-N 3.15Å
491R40.8Very low51.3Low244 Ų244159.8 Ų159.892%0.92177%0.766SS**PPolyproline II helixtrans-47.4122167-113.3174.7165.7168.1-5.3106.7K489 R493K489-R491 PolarHBondContact O-N 2.97Å; R491-R493 PolarHBondContact O-N 2.87Å; R491-R493 VanDerWaalsContact O-N 3.15Å
492K43Very low48.5Very low207 Ų207165.4 Ų165.490%0.980%0.796SS**PPolyproline II helixtrans-47.6124.8171.9-80.2-175.2170.9-170.20108.1P490 L494P490-K492 PolarHBondContact O-N 3.24Å; P490-K492 VanDerWaalsContact O-N 3.15Å; K492-L494 PolarHBondContact O-N 2.97Å
493R41.6Very low45.7Very low241 Ų241175.4 Ų175.491%0.90984%0.84SS**PPolyproline II helixtrans-53.2129.4170.5-68.3179177.5178.1-1.9108.2R491R491-R493 PolarHBondContact O-N 2.87Å; R491-R493 VanDerWaalsContact O-N 3.15Å
494L38.7Very low43.4Very low163 Ų163169.9 Ų169.985%0.85383%0.833SS**PPolyproline II helixtrans-64.5140.9163.9-74.2160.3000107.7K492K492-L494 PolarHBondContact O-N 2.97Å
495P51.8Low42Very low120 Ų120171.9 Ų171.978%0.77984%0.838SS**PPolyproline II helixtrans-66.4139.7168.5-5.621.7000109.2
496M43.4Very low41.6Very low264 Ų264181.6 Ų181.6100%1.385%0.853SS**  trans-63.10163.3-107.3-177.3-90.700110.4

Retrieved 496 of 496 residues in 745.6 ms (Link to these results)