A0A087YCW8_POEFO Loading...

Sodium-dependent multivitamin transporter

Sodium-dependent multivitamin transporter that mediates the electrogenic transport of pantothenate, biotin, lipoate and iodide. Functions as a Na(+)-coupled substrate symporter where the stoichiometry of Na(+):substrate is 2:1, creating an electrochemical Na(+) gradient used as driving force for substrate uptake. Required for biotin and pantothenate uptake in the intestine across the brush border membrane. Plays a role in the maintenance of intestinal mucosa integrity, by providing the gut mucosa with biotin. Contributes to the luminal uptake of biotin and pantothenate into the brain across the blood-brain barrier.

AlphaFold DB , UniProt , Accession A0A087YCW8, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 614 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37.6	Very low	54.5	Low	182 Å²	182	95.5 Å²	95.5	90%	0.897	54%	0.535	S	S	*	.				0	129.5	0	-76.9	-179.7	172.5	0	0	106.9	P3 L313	M1-P3 WeakPolarHBondContact O-CD 3.39Å; M1-L313 HydrophobicContact CE-CD1 4.44Å
2	D	25.7	Very low	57.6	Low	123 Å²	123	93.6 Å²	93.6	66%	0.658	53%	0.527	S	S	*	.			trans	-64.3	117.2	172.3	-144.8	-9.5	0	0	0	107.9	S4 N5	D2-S4 PolarHBondContact O-N 3.41Å; D2-S4 VanDerWaalsContact O-N 3.15Å; D2-N5 PolarHBondContact O-N 3.19Å
3	P	36.5	Very low	60.1	Low	95 Å²	95	86.8 Å²	86.8	62%	0.617	49%	0.489	S	S	*	.	G	3₁₀ helix	trans	-67.5	-13.6	-171.3	19.2	-24.4	0	0	0	113.6	M1 N5	M1-P3 WeakPolarHBondContact O-CD 3.39Å; P3-N5 VanDerWaalsContact C-N 3.33Å; P3-N5 PolarHBondContact O-N 2.99Å
4	S	33.5	Very low	62.2	Low	96 Å²	96	87.6 Å²	87.6	67%	0.671	48%	0.481	S	S	*	.	G	3₁₀ helix	trans	-77	-10.5	-179.9	53.9	0	0	0	0	115	D2	D2-S4 PolarHBondContact O-N 3.41Å; D2-S4 VanDerWaalsContact O-N 3.15Å
5	N	43.5	Very low	64.2	Low	142 Å²	142	87.3 Å²	87.3	76%	0.759	48%	0.482	S	S	*	.	G	3₁₀ helix	trans	-121.8	23.3	-176.5	-117.9	-10.1	0	0	0	112.9	D2 P3 K7	D2-N5 PolarHBondContact O-N 3.19Å; P3-N5 VanDerWaalsContact C-N 3.33Å; P3-N5 PolarHBondContact O-N 2.99Å; N5-K7 PolarHBondContact O-N 3.05Å
6	Q	50.1	Low	66	Low	87 Å²	87	84.4 Å²	84.4	41%	0.407	47%	0.468	S	S	.	.			trans	-68.6	121.3	175.4	-76.3	-173.8	-2.7	0	0	110.1	H8	Q6-H8 PolarHBondContact O-CD2 2.88Å; Q6-H8 PolarHBondContact O-N 2.71Å; Q6-H8 PolarHBondContact O-NE2 3.26Å
7	K	58.5	Low	67.5	Low	61 Å²	61	80.8 Å²	80.8	27%	0.265	45%	0.446	S	S	.	.			trans	-72.8	96.7	177.9	-63	178.9	-177.4	179	0	108.1	N5 D328 Q331	N5-K7 PolarHBondContact O-N 3.05Å; K7-D328 VanDerWaalsContact NZ-CG 3.31Å; K7-D328 IonicContact NZ-OD1 2.61Å; K7-D328 PolarHBondContact NZ-OD1 3.44Å; K7-Q331 VanDerWaalsContact CE-OE1 3.25Å
8	H	63.6	Low	68.7	Low	126 Å²	126	79.3 Å²	79.3	58%	0.583	45%	0.446	S	S	*	.	P	Polyproline II helix	trans	-85.6	148.7	-174	-67.9	-67.5	0	0	0	112.9	Q6 S10	Q6-H8 PolarHBondContact O-CD2 2.88Å; Q6-H8 PolarHBondContact O-N 2.71Å; Q6-H8 PolarHBondContact O-NE2 3.26Å; H8-S10 PolarHBondContact O-N 2.98Å
9	F	78.1	Confident	70	Confident	17 Å²	17	81.1 Å²	81.1	8%	0.075	45%	0.454	C	S	.	.	P	Polyproline II helix	trans	-57	133.9	165.5	-95.5	30.7	0	0	0	110.5	D13 Y14 A156 T157 M327 P337 V341	F9-D13 HydrophobicContact CB-CB 4.1Å; F9-D13 HydrophobicContact CD1-CB 4.33Å; F9-D13 HydrophobicContact CD2-CB 3.54Å; F9-D13 HydrophobicContact CE2-CB 3.9Å; F9-D13 HydrophobicContact CG-CB 3.75Å; F9-D13 HydrophobicContact CZ-CB 4.4Å; F9-Y14 HydrophobicContact CB-CD2 3.87Å; F9-Y14 HydrophobicContact CB-CE1 4.42Å; F9-Y14 HydrophobicContact CB-CE2 3.32Å; F9-Y14 HydrophobicContact CD2-CD1 4Å; F9-Y14 HydrophobicContact CD2-CD2 4.24Å; F9-Y14 AromaticContact CD2-CE1 3.89Å; F9-Y14 HydrophobicContact CD2-CE1 3.89Å; F9-Y14 HydrophobicContact CD2-CE2 4.14Å; F9-Y14 HydrophobicContact CD2-CG 4.18Å; F9-Y14 AromaticContact CD2-CZ 3.96Å; F9-Y14 HydrophobicContact CG-CE2 4.22Å; F9-A156 HydrophobicContact CE1-CB 4.36Å; F9-T157 HydrophobicContact CB-CG2 4.15Å; F9-T157 HydrophobicContact CD1-CG2 3.49Å; F9-T157 VanDerWaalsContact CD1-CG2 3.49Å; F9-T157 HydrophobicContact CD2-CG2 3.81Å; F9-T157 HydrophobicContact CE1-CG2 3.82Å; F9-T157 HydrophobicContact CE2-CG2 4.12Å; F9-T157 HydrophobicContact CG-CG2 3.52Å; F9-T157 HydrophobicContact CZ-CG2 4.14Å; F9-M327 HydrophobicContact CD1-SD 4.48Å; F9-M327 HydrophobicContact CE1-CE 3.95Å; F9-M327 HydrophobicContact CE1-SD 3.93Å; F9-P337 HydrophobicContact CD1-CB 4.28Å; F9-P337 HydrophobicContact CE1-CB 3.78Å; F9-P337 HydrophobicContact CZ-CB 4.28Å; F9-V341 HydrophobicContact CE1-CG2 4.19Å; F9-V341 HydrophobicContact CE2-CG2 4.46Å; F9-V341 HydrophobicContact CZ-CB 3.99Å; F9-V341 HydrophobicContact CZ-CG2 3.51Å
10	S	84.3	Confident	71	Confident	42 Å²	42	78.7 Å²	78.7	29%	0.294	44%	0.44	S	S	.	.	P	Polyproline II helix	trans	-74.4	162	165.1	72.1	0	0	0	0	110.3	H8 V12 D13 Y14	H8-S10 PolarHBondContact O-N 2.98Å; S10-V12 PolarHBondContact O-N 3.41Å; S10-D13 WeakPolarHBondContact CB-OD2 3.13Å; S10-D13 PolarHBondContact N-OD2 2.92Å; S10-D13 WeakPolarHBondContact O-CB 3.3Å; S10-D13 PolarHBondContact O-N 3.42Å; S10-D13 VanDerWaalsContact OG-CG 3.27Å; S10-D13 PolarHBondContact OG-N 3.24Å; S10-D13 PolarHBondContact OG-OD2 3.05Å; S10-Y14 WeakPolarHBondContact O-CD2 3.3Å; S10-Y14 PolarHBondContact O-N 3.11Å
11	A	88.1	Confident	71.8	Confident	80 Å²	80	76.6 Å²	76.6	66%	0.661	43%	0.428	S	S	*	.	H	α-helix	trans	-56.2	-34.5	174.4	0	0	0	0	0	112.3	D13 Y14 V15	A11-D13 VanDerWaalsContact C-N 3.32Å; A11-D13 PolarHBondContact O-N 3.25Å; A11-Y14 PolarHBondContact O-N 3.45Å; A11-V15 WeakPolarHBondContact O-CG2 3.37Å; A11-V15 PolarHBondContact O-N 3.16Å; A11-V15 VanDerWaalsContact O-N 3.07Å
12	V	91.5	Very high	74.2	Confident	72 Å²	72	70.8 Å²	70.8	44%	0.436	41%	0.409	S	S	.	.	H	α-helix	trans	-64.4	-37.6	177.5	-176.8	0	0	0	0	111.2	S10 Y14 V15 V16 P334	S10-V12 PolarHBondContact O-N 3.41Å; V12-Y14 PolarHBondContact O-N 2.74Å; V12-V15 PolarHBondContact O-N 3.35Å; V12-V16 HydrophobicContact CG1-CG2 4.33Å; V12-V16 WeakPolarHBondContact O-CG2 3.36Å; V12-V16 PolarHBondContact O-N 3.13Å; V12-P334 HydrophobicContact CB-CB 4.04Å; V12-P334 HydrophobicContact CG1-CB 4.28Å; V12-P334 HydrophobicContact CG2-CB 4.26Å
13	D	90.3	Very high	77.3	Confident	6 Å²	6	66.7 Å²	66.7	3%	0.032	39%	0.392	C	S	.	.	H	α-helix	trans	-62.9	-43.5	177.7	-62.4	-52.6	0	0	0	111.6	F9 S10 A11 V15 V16 F17 G335 P337 G338	F9-D13 HydrophobicContact CB-CB 4.1Å; F9-D13 HydrophobicContact CD1-CB 4.33Å; F9-D13 HydrophobicContact CD2-CB 3.54Å; F9-D13 HydrophobicContact CE2-CB 3.9Å; F9-D13 HydrophobicContact CG-CB 3.75Å; F9-D13 HydrophobicContact CZ-CB 4.4Å; S10-D13 WeakPolarHBondContact CB-OD2 3.13Å; S10-D13 PolarHBondContact N-OD2 2.92Å; S10-D13 WeakPolarHBondContact O-CB 3.3Å; S10-D13 PolarHBondContact O-N 3.42Å; S10-D13 VanDerWaalsContact OG-CG 3.27Å; S10-D13 PolarHBondContact OG-N 3.24Å; S10-D13 PolarHBondContact OG-OD2 3.05Å; A11-D13 VanDerWaalsContact C-N 3.32Å; A11-D13 PolarHBondContact O-N 3.25Å; D13-V15 VanDerWaalsContact C-N 3.34Å; D13-V15 PolarHBondContact O-N 3.14Å; D13-V16 PolarHBondContact O-N 3.37Å; D13-F17 WeakPolarHBondContact O-CB 3.42Å; D13-F17 PolarHBondContact O-N 3.2Å; D13-G335 WeakPolarHBondContact OD1-CA 3.04Å; D13-G335 PolarHBondContact OD1-N 2.89Å; D13-P337 WeakPolarHBondContact OD1-CD 3.45Å; D13-G338 WeakPolarHBondContact O-CA 3.33Å; D13-G338 PolarHBondContact OD1-N 3.29Å
14	Y	89.2	Confident	79.7	Confident	98 Å²	98	62.2 Å²	62.2	38%	0.384	36%	0.362	S	S	.	.	H	α-helix	trans	-63.2	-40.1	174.6	-73.9	-70.1	0	0	0	112.3	F9 S10 A11 V12 A18	F9-Y14 HydrophobicContact CB-CD2 3.87Å; F9-Y14 HydrophobicContact CB-CE1 4.42Å; F9-Y14 HydrophobicContact CB-CE2 3.32Å; F9-Y14 HydrophobicContact CD2-CD1 4Å; F9-Y14 HydrophobicContact CD2-CD2 4.24Å; F9-Y14 AromaticContact CD2-CE1 3.89Å; F9-Y14 HydrophobicContact CD2-CE1 3.89Å; F9-Y14 HydrophobicContact CD2-CE2 4.14Å; F9-Y14 HydrophobicContact CD2-CG 4.18Å; F9-Y14 AromaticContact CD2-CZ 3.96Å; F9-Y14 HydrophobicContact CG-CE2 4.22Å; S10-Y14 WeakPolarHBondContact O-CD2 3.3Å; S10-Y14 PolarHBondContact O-N 3.11Å; A11-Y14 PolarHBondContact O-N 3.45Å; V12-Y14 PolarHBondContact O-N 2.74Å; Y14-A18 WeakPolarHBondContact O-CB 3.35Å; Y14-A18 PolarHBondContact O-N 3.45Å
15	V	92.9	Very high	82.2	Confident	82 Å²	82	59.4 Å²	59.4	50%	0.497	34%	0.341	S	S	.	.	H	α-helix	trans	-65.1	-49.1	177.7	171.4	0	0	0	0	111	A11 V12 D13 F17 A18 L19	A11-V15 WeakPolarHBondContact O-CG2 3.37Å; A11-V15 PolarHBondContact O-N 3.16Å; A11-V15 VanDerWaalsContact O-N 3.07Å; V12-V15 PolarHBondContact O-N 3.35Å; D13-V15 VanDerWaalsContact C-N 3.34Å; D13-V15 PolarHBondContact O-N 3.14Å; V15-F17 VanDerWaalsContact C-N 3.34Å; V15-F17 PolarHBondContact O-N 3.49Å; V15-A18 PolarHBondContact O-N 2.87Å; V15-L19 HydrophobicContact CG1-CD1 3.7Å; V15-L19 HydrophobicContact CG1-CG 4.21Å; V15-L19 WeakPolarHBondContact O-CB 3.45Å; V15-L19 VanDerWaalsContact O-CG 3.24Å; V15-L19 WeakPolarHBondContact O-CG 3.14Å; V15-L19 PolarHBondContact O-N 3.44Å
16	V	93	Very high	84.3	Confident	41 Å²	41	54.4 Å²	54.4	25%	0.248	32%	0.323	C	S	.	.	H	α-helix	trans	-60	-46.2	178	171.3	0	0	0	0	110.7	V12 D13 L19 L20 L339	V12-V16 HydrophobicContact CG1-CG2 4.33Å; V12-V16 WeakPolarHBondContact O-CG2 3.36Å; V12-V16 PolarHBondContact O-N 3.13Å; D13-V16 PolarHBondContact O-N 3.37Å; V16-L19 PolarHBondContact O-N 3.29Å; V16-L20 HydrophobicContact CG1-CD1 3.92Å; V16-L20 WeakPolarHBondContact O-CG 3.37Å; V16-L20 PolarHBondContact O-N 3.44Å; V16-L20 VanDerWaalsContact O-N 3.08Å; V16-L339 HydrophobicContact CG1-CB 4.29Å
17	F	90.5	Very high	86.1	Confident	24 Å²	24	52.4 Å²	52.4	11%	0.105	32%	0.315	C	S	.	.	H	α-helix	trans	-58.4	-50.9	176.4	172	-119	0	0	0	112.1	D13 V15 L19 L20 L21 V341 A342 F345	D13-F17 WeakPolarHBondContact O-CB 3.42Å; D13-F17 PolarHBondContact O-N 3.2Å; V15-F17 VanDerWaalsContact C-N 3.34Å; V15-F17 PolarHBondContact O-N 3.49Å; F17-L19 PolarHBondContact O-N 3.3Å; F17-L20 PolarHBondContact O-N 2.88Å; F17-L21 HydrophobicContact CD1-CD1 4.47Å; F17-L21 HydrophobicContact CD2-CD1 4.19Å; F17-L21 HydrophobicContact CD2-CG 4.3Å; F17-L21 HydrophobicContact CE1-CD1 3.84Å; F17-L21 HydrophobicContact CE2-CD1 3.5Å; F17-L21 VanDerWaalsContact CE2-CD1 3.5Å; F17-L21 HydrophobicContact CE2-CD2 4.44Å; F17-L21 HydrophobicContact CE2-CG 3.91Å; F17-L21 HydrophobicContact CZ-CD1 3.31Å; F17-L21 HydrophobicContact CZ-CG 4.24Å; F17-L21 WeakPolarHBondContact O-CG 3.17Å; F17-L21 PolarHBondContact O-N 2.9Å; F17-L21 VanDerWaalsContact O-N 3.1Å; F17-V341 HydrophobicContact CD2-CB 4.39Å; F17-V341 HydrophobicContact CD2-CG1 3.89Å; F17-V341 HydrophobicContact CE2-CG1 3.7Å; F17-V341 HydrophobicContact CZ-CG1 4.21Å; F17-A342 HydrophobicContact CD2-CB 4.11Å; F17-F345 HydrophobicContact CE2-CB 4.27Å; F17-F345 HydrophobicContact CE2-CD1 4.32Å; F17-F345 AromaticContact CE2-CD2 3.78Å; F17-F345 HydrophobicContact CE2-CD2 3.78Å; F17-F345 HydrophobicContact CE2-CE2 4.14Å; F17-F345 AromaticContact CE2-CG 3.87Å; F17-F345 HydrophobicContact CE2-CG 3.87Å; F17-F345 HydrophobicContact CZ-CD1 4.22Å; F17-F345 HydrophobicContact CZ-CD2 4.11Å; F17-F345 HydrophobicContact CZ-CE1 4.13Å; F17-F345 HydrophobicContact CZ-CE2 4.05Å; F17-F345 HydrophobicContact CZ-CG 4.19Å; F17-F345 HydrophobicContact CZ-CZ 4.05Å
18	A	90.4	Very high	87.3	Confident	53 Å²	53	49.5 Å²	49.5	44%	0.438	30%	0.302	S	S	.	.	H	α-helix	trans	-63.8	-40.5	-179.3	0	0	0	0	0	112.3	Y14 V15 L21 A22	Y14-A18 WeakPolarHBondContact O-CB 3.35Å; Y14-A18 PolarHBondContact O-N 3.45Å; V15-A18 PolarHBondContact O-N 2.87Å; A18-L21 PolarHBondContact O-N 2.97Å; A18-A22 WeakPolarHBondContact O-CB 3.44Å; A18-A22 PolarHBondContact O-N 2.84Å
19	L	92.9	Very high	88.3	Confident	114 Å²	114	46.3 Å²	46.3	60%	0.597	29%	0.289	S	S	*	.	H	α-helix	trans	-64.3	-42.7	178.3	-74.9	173.3	0	0	0	112.1	V15 V16 F17 A22 A23	V15-L19 HydrophobicContact CG1-CD1 3.7Å; V15-L19 HydrophobicContact CG1-CG 4.21Å; V15-L19 WeakPolarHBondContact O-CB 3.45Å; V15-L19 VanDerWaalsContact O-CG 3.24Å; V15-L19 WeakPolarHBondContact O-CG 3.14Å; V15-L19 PolarHBondContact O-N 3.44Å; V16-L19 PolarHBondContact O-N 3.29Å; F17-L19 PolarHBondContact O-N 3.3Å; L19-A22 PolarHBondContact O-N 3.05Å; L19-A23 WeakPolarHBondContact O-CB 3.43Å; L19-A23 PolarHBondContact O-N 3.42Å
20	L	90.5	Very high	88.7	Confident	33 Å²	33	52.4 Å²	52.4	17%	0.173	31%	0.312	C	S	.	.	H	α-helix	trans	-68.6	-36.5	178.9	-70.4	171.6	0	0	0	112.2	V16 F17 S24 F190 V194 L339 A342	V16-L20 HydrophobicContact CG1-CD1 3.92Å; V16-L20 WeakPolarHBondContact O-CG 3.37Å; V16-L20 PolarHBondContact O-N 3.44Å; V16-L20 VanDerWaalsContact O-N 3.08Å; F17-L20 PolarHBondContact O-N 2.88Å; L20-S24 PolarHBondContact O-N 2.75Å; L20-S24 VanDerWaalsContact O-N 3.12Å; L20-S24 PolarHBondContact O-OG 3.21Å; L20-F190 HydrophobicContact CD2-CZ 3.9Å; L20-V194 HydrophobicContact CD1-CG1 4.13Å; L20-V194 HydrophobicContact CD2-CG2 4.08Å; L20-L339 HydrophobicContact CD1-CD1 3.7Å; L20-A342 HydrophobicContact CB-CB 3.82Å; L20-A342 HydrophobicContact CD1-CB 3.38Å; L20-A342 HydrophobicContact CG-CB 4.24Å
21	L	86.5	Confident	88.5	Confident	35 Å²	35	53.9 Å²	53.9	18%	0.183	31%	0.312	C	S	.	.	H	α-helix	trans	-66.8	-46.3	171	-73	-173.1	0	0	0	112	F17 A18 A23 S24 V25 F345 L349	F17-L21 HydrophobicContact CD1-CD1 4.47Å; F17-L21 HydrophobicContact CD2-CD1 4.19Å; F17-L21 HydrophobicContact CD2-CG 4.3Å; F17-L21 HydrophobicContact CE1-CD1 3.84Å; F17-L21 HydrophobicContact CE2-CD1 3.5Å; F17-L21 VanDerWaalsContact CE2-CD1 3.5Å; F17-L21 HydrophobicContact CE2-CD2 4.44Å; F17-L21 HydrophobicContact CE2-CG 3.91Å; F17-L21 HydrophobicContact CZ-CD1 3.31Å; F17-L21 HydrophobicContact CZ-CG 4.24Å; F17-L21 WeakPolarHBondContact O-CG 3.17Å; F17-L21 PolarHBondContact O-N 2.9Å; F17-L21 VanDerWaalsContact O-N 3.1Å; A18-L21 PolarHBondContact O-N 2.97Å; L21-A23 VanDerWaalsContact C-N 3.28Å; L21-A23 PolarHBondContact O-N 3.13Å; L21-S24 WeakPolarHBondContact O-CB 3.3Å; L21-S24 PolarHBondContact O-N 3.37Å; L21-S24 VanDerWaalsContact O-N 3.15Å; L21-V25 WeakPolarHBondContact O-CG2 3.4Å; L21-V25 PolarHBondContact O-N 2.85Å; L21-F345 HydrophobicContact CD1-CD1 4.42Å; L21-F345 HydrophobicContact CD2-CB 3.81Å; L21-F345 HydrophobicContact CD2-CD1 4.39Å; L21-F345 HydrophobicContact CD2-CG 4.44Å; L21-L349 HydrophobicContact CD2-CD1 3.78Å
22	A	89.6	Confident	87.9	Confident	60 Å²	60	50.9 Å²	50.9	50%	0.496	29%	0.288	S	S	.	.	H	α-helix	trans	-61.4	-37.6	177.6	0	0	0	0	0	111.6	A18 L19 V25 G26	A18-A22 WeakPolarHBondContact O-CB 3.44Å; A18-A22 PolarHBondContact O-N 2.84Å; L19-A22 PolarHBondContact O-N 3.05Å; A22-V25 PolarHBondContact O-N 2.99Å; A22-G26 WeakPolarHBondContact O-CA 3.34Å; A22-G26 PolarHBondContact O-N 3.27Å
23	A	90.1	Very high	87.2	Confident	37 Å²	37	54.1 Å²	54.1	31%	0.306	30%	0.301	S	S	.	.	H	α-helix	trans	-63.4	-44.1	173.6	0	0	0	0	0	111.8	L19 L21 V25 G26 I27 F190	L19-A23 WeakPolarHBondContact O-CB 3.43Å; L19-A23 PolarHBondContact O-N 3.42Å; L21-A23 VanDerWaalsContact C-N 3.28Å; L21-A23 PolarHBondContact O-N 3.13Å; A23-V25 PolarHBondContact O-N 2.86Å; A23-G26 PolarHBondContact O-N 3Å; A23-I27 VanDerWaalsContact O-CG1 3.3Å; A23-I27 WeakPolarHBondContact O-CG1 3.27Å; A23-I27 PolarHBondContact O-N 3.26Å; A23-F190 HydrophobicContact CB-CE1 3.9Å; A23-F190 HydrophobicContact CB-CE2 4.47Å; A23-F190 HydrophobicContact CB-CZ 3.7Å
24	S	86.4	Confident	86	Confident	0 Å²	0	57.1 Å²	57.1	0%	0	32%	0.323	C	S	.	.	H	α-helix	trans	-60.1	-47.6	176.1	-59.6	0	0	0	0	111.5	L20 L21 G28 T187	L20-S24 PolarHBondContact O-N 2.75Å; L20-S24 VanDerWaalsContact O-N 3.12Å; L20-S24 PolarHBondContact O-OG 3.21Å; L21-S24 WeakPolarHBondContact O-CB 3.3Å; L21-S24 PolarHBondContact O-N 3.37Å; L21-S24 VanDerWaalsContact O-N 3.15Å; S24-G28 PolarHBondContact O-N 2.85Å; S24-T187 WeakPolarHBondContact O-CG2 3.21Å
25	V	85.6	Confident	84.5	Confident	38 Å²	38	53.3 Å²	53.3	23%	0.23	31%	0.314	C	S	.	.	H	α-helix	trans	-64.7	-41.7	176.7	175.3	0	0	0	0	111	L21 A22 A23 I27 G28 L29 V171	L21-V25 WeakPolarHBondContact O-CG2 3.4Å; L21-V25 PolarHBondContact O-N 2.85Å; A22-V25 PolarHBondContact O-N 2.99Å; A23-V25 PolarHBondContact O-N 2.86Å; V25-I27 PolarHBondContact O-N 2.64Å; V25-G28 PolarHBondContact O-N 2.97Å; V25-G28 VanDerWaalsContact O-N 3.17Å; V25-L29 HydrophobicContact CG1-CD1 3.74Å; V25-L29 HydrophobicContact CG1-CG 4.07Å; V25-L29 WeakPolarHBondContact O-CB 3.34Å; V25-L29 WeakPolarHBondContact O-CG 3.28Å; V25-L29 PolarHBondContact O-N 2.93Å; V25-V171 HydrophobicContact CG2-CG1 3.5Å
26	G	88.4	Confident	82.8	Confident	36 Å²	36	52.7 Å²	52.7	37%	0.371	32%	0.324	S	S	.	.	H	α-helix	trans	-61.5	-42.5	179.3	0	0	0	0	0	112.8	A22 A23 L29 Y30	A22-G26 WeakPolarHBondContact O-CA 3.34Å; A22-G26 PolarHBondContact O-N 3.27Å; A23-G26 PolarHBondContact O-N 3Å; G26-L29 PolarHBondContact O-N 3.01Å; G26-Y30 WeakPolarHBondContact O-CB 3.49Å; G26-Y30 PolarHBondContact O-N 2.96Å
27	I	87.4	Confident	81	Confident	45 Å²	45	58.4 Å²	58.4	23%	0.231	34%	0.341	C	S	.	.	H	α-helix	trans	-62.1	-45.7	173.1	-66.4	164.1	0	0	0	110	A23 V25 Y30 Y31 W186 T187 F190	A23-I27 VanDerWaalsContact O-CG1 3.3Å; A23-I27 WeakPolarHBondContact O-CG1 3.27Å; A23-I27 PolarHBondContact O-N 3.26Å; V25-I27 PolarHBondContact O-N 2.64Å; I27-Y30 PolarHBondContact O-N 3.4Å; I27-Y31 HydrophobicContact CG2-CD2 4.07Å; I27-Y31 HydrophobicContact CG2-CE2 4.2Å; I27-Y31 WeakPolarHBondContact O-CD2 3.17Å; I27-Y31 PolarHBondContact O-N 3.28Å; I27-Y31 VanDerWaalsContact O-N 3.14Å; I27-W186 HydrophobicContact CG2-CB 4.09Å; I27-T187 HydrophobicContact CB-CG2 4.06Å; I27-T187 HydrophobicContact CG2-CG2 3.85Å; I27-F190 HydrophobicContact CD1-CB 3.61Å; I27-F190 HydrophobicContact CD1-CD1 4.07Å; I27-F190 HydrophobicContact CD1-CD2 4.13Å; I27-F190 HydrophobicContact CD1-CG 3.66Å
28	G	83.4	Confident	79.6	Confident	0 Å²	0	58.7 Å²	58.7	0%	0	34%	0.343	C	S	.	.	H	α-helix	trans	-59.2	-47.6	177.4	0	0	0	0	0	112.8	S24 V25 A32	S24-G28 PolarHBondContact O-N 2.85Å; V25-G28 PolarHBondContact O-N 2.97Å; V25-G28 VanDerWaalsContact O-N 3.17Å; G28-A32 WeakPolarHBondContact O-CB 3.47Å; G28-A32 PolarHBondContact O-N 3.33Å
29	L	85.3	Confident	78.4	Confident	60 Å²	60	65.1 Å²	65.1	31%	0.314	36%	0.355	S	S	.	.	H	α-helix	trans	-68.4	-37.8	178.4	-71	177.6	0	0	0	112.6	V25 G26 A32 L33 L178	V25-L29 HydrophobicContact CG1-CD1 3.74Å; V25-L29 HydrophobicContact CG1-CG 4.07Å; V25-L29 WeakPolarHBondContact O-CB 3.34Å; V25-L29 WeakPolarHBondContact O-CG 3.28Å; V25-L29 PolarHBondContact O-N 2.93Å; G26-L29 PolarHBondContact O-N 3.01Å; L29-A32 WeakPolarHBondContact O-CB 3.48Å; L29-A32 PolarHBondContact O-N 3.24Å; L29-L33 WeakPolarHBondContact O-CB 3.48Å; L29-L33 VanDerWaalsContact O-CG 3.28Å; L29-L33 WeakPolarHBondContact O-CG 3.41Å; L29-L33 PolarHBondContact O-N 3.17Å; L29-L178 HydrophobicContact CD2-CD1 3.68Å
30	Y	86.2	Confident	77.5	Confident	144 Å²	144	62.1 Å²	62.1	57%	0.565	34%	0.342	S	S	*	.	H	α-helix	trans	-58.7	-49.8	175.5	172.5	-97.8	0	0	0	110.9	G26 I27 A32 L33 S34	G26-Y30 WeakPolarHBondContact O-CB 3.49Å; G26-Y30 PolarHBondContact O-N 2.96Å; I27-Y30 PolarHBondContact O-N 3.4Å; Y30-A32 VanDerWaalsContact C-N 3.27Å; Y30-A32 PolarHBondContact O-N 3.37Å; Y30-L33 PolarHBondContact O-N 3.46Å; Y30-S34 VanDerWaalsContact CD2-OG 3.29Å; Y30-S34 WeakPolarHBondContact CD2-OG 3.43Å; Y30-S34 VanDerWaalsContact CE2-OG 3.24Å; Y30-S34 WeakPolarHBondContact CE2-OG 3.3Å; Y30-S34 VanDerWaalsContact O-CB 3.24Å; Y30-S34 WeakPolarHBondContact O-CB 3.24Å; Y30-S34 PolarHBondContact O-N 3.27Å; Y30-S34 PolarHBondContact O-OG 3.23Å
31	Y	80.3	Confident	76.6	Confident	74 Å²	74	60.7 Å²	60.7	29%	0.29	33%	0.334	S	S	.	.	H	α-helix	trans	-68.8	-25.2	177.1	-81.8	-75.5	0	0	0	113.3	I27 W186	I27-Y31 HydrophobicContact CG2-CD2 4.07Å; I27-Y31 HydrophobicContact CG2-CE2 4.2Å; I27-Y31 WeakPolarHBondContact O-CD2 3.17Å; I27-Y31 PolarHBondContact O-N 3.28Å; I27-Y31 VanDerWaalsContact O-N 3.14Å; Y31-W186 HydrophobicContact CD2-CB 4.03Å; Y31-W186 HydrophobicContact CD2-CG 4.3Å; Y31-W186 AromaticContact CE1-CD1 3.83Å; Y31-W186 HydrophobicContact CE1-CG 4.49Å; Y31-W186 HydrophobicContact CE2-CB 3.64Å; Y31-W186 AromaticContact CE2-CD1 3.7Å; Y31-W186 HydrophobicContact CE2-CD2 4.27Å; Y31-W186 AromaticContact CE2-CG 3.59Å; Y31-W186 HydrophobicContact CE2-CG 3.59Å; Y31-W186 AromaticContact CZ-CD1 3.44Å; Y31-W186 VanDerWaalsContact CZ-CD1 3.44Å; Y31-W186 AromaticContact CZ-CG 3.7Å; Y31-W186 AromaticContact CZ-NE1 3.73Å; Y31-W186 PolarHBondContact OH-NE1 3.25Å
32	A	74.8	Confident	76	Confident	17 Å²	17	64.2 Å²	64.2	14%	0.14	35%	0.35	C	S	.	.	H	α-helix	trans	-70.7	-44.1	171.6	0	0	0	0	0	112.9	G28 L29 Y30 L178	G28-A32 WeakPolarHBondContact O-CB 3.47Å; G28-A32 PolarHBondContact O-N 3.33Å; L29-A32 WeakPolarHBondContact O-CB 3.48Å; L29-A32 PolarHBondContact O-N 3.24Å; Y30-A32 VanDerWaalsContact C-N 3.27Å; Y30-A32 PolarHBondContact O-N 3.37Å; A32-L178 HydrophobicContact CB-CB 3.96Å; A32-L178 WeakPolarHBondContact CB-O 3.08Å
33	L	77.8	Confident	75.3	Confident	139 Å²	139	62.8 Å²	62.8	73%	0.728	33%	0.333	S	S	*	.	H	α-helix	trans	-95	-38.6	-167.9	-64.7	174.4	0	0	0	113.7	L29 Y30 G35	L29-L33 WeakPolarHBondContact O-CB 3.48Å; L29-L33 VanDerWaalsContact O-CG 3.28Å; L29-L33 WeakPolarHBondContact O-CG 3.41Å; L29-L33 PolarHBondContact O-N 3.17Å; Y30-L33 PolarHBondContact O-N 3.46Å; L33-G35 PolarHBondContact O-N 3.06Å
34	S	65.6	Low	74.7	Confident	69 Å²	69	61.3 Å²	61.3	48%	0.483	32%	0.32	S	S	.	.	S	Bend	trans	-75.4	7.2	-176.8	-59.3	0	0	0	0	113.8	Y30	Y30-S34 VanDerWaalsContact CD2-OG 3.29Å; Y30-S34 WeakPolarHBondContact CD2-OG 3.43Å; Y30-S34 VanDerWaalsContact CE2-OG 3.24Å; Y30-S34 WeakPolarHBondContact CE2-OG 3.3Å; Y30-S34 VanDerWaalsContact O-CB 3.24Å; Y30-S34 WeakPolarHBondContact O-CB 3.24Å; Y30-S34 PolarHBondContact O-N 3.27Å; Y30-S34 PolarHBondContact O-OG 3.23Å
35	G	56.8	Low	74.2	Confident	19 Å²	19	61.4 Å²	61.4	20%	0.196	32%	0.32	C	S	.	.			trans	-93.1	-51.9	-168.3	0	0	0	0	0	115.9	L33 R37	L33-G35 PolarHBondContact O-N 3.06Å; G35-R37 VanDerWaalsContact C-CB 3.49Å; G35-R37 VanDerWaalsContact O-CB 3.22Å; G35-R37 WeakPolarHBondContact O-CB 3.36Å; G35-R37 VanDerWaalsContact O-CD 3.27Å; G35-R37 WeakPolarHBondContact O-CD 3.29Å; G35-R37 WeakPolarHBondContact O-CG 3.28Å; G35-R37 PolarHBondContact O-N 2.92Å
36	G	56.5	Low	73.9	Confident	68 Å²	68	59.6 Å²	59.6	70%	0.701	31%	0.31	S	S	*	.	S	Bend	trans	54.4	13.4	-152.3	0	0	0	0	0	113.2
37	R	56.4	Low	73.4	Confident	161 Å²	161	57.9 Å²	57.9	61%	0.608	29%	0.292	S	S	*	.			trans	-125.2	48.1	-151.6	-91.5	167.9	-171.6	152.2	0.3	110.2	G35 E43	G35-R37 VanDerWaalsContact C-CB 3.49Å; G35-R37 VanDerWaalsContact O-CB 3.22Å; G35-R37 WeakPolarHBondContact O-CB 3.36Å; G35-R37 VanDerWaalsContact O-CD 3.27Å; G35-R37 WeakPolarHBondContact O-CD 3.29Å; G35-R37 WeakPolarHBondContact O-CG 3.28Å; G35-R37 PolarHBondContact O-N 2.92Å; R37-E43 WeakPolarHBondContact CA-OE1 3.38Å; R37-E43 WeakPolarHBondContact CA-OE2 3.46Å; R37-E43 WeakPolarHBondContact CB-OE1 3.35Å; R37-E43 VanDerWaalsContact CG-OE1 3.24Å; R37-E43 WeakPolarHBondContact CG-OE1 3.46Å; R37-E43 VanDerWaalsContact O-CG 3.29Å; R37-E43 WeakPolarHBondContact O-CG 3.38Å; R37-E43 VanDerWaalsContact O-OE2 3.09Å
38	Q	61.2	Low	73	Confident	31 Å²	31	59 Å²	59	15%	0.145	30%	0.298	C	S	.	.			trans	-144.7	32.1	170.9	-66.7	-165.2	-14.3	0	0	110.9	T40 E43 L178 G179	Q38-T40 VanDerWaalsContact C-N 3.31Å; Q38-E43 PolarHBondContact N-OE2 2.86Å; Q38-L178 PolarHBondContact NE2-O 3.07Å; Q38-L178 PolarHBondContact OE1-O 3.18Å; Q38-G179 PolarHBondContact NE2-O 2.87Å
39	R	63.8	Low	73	Confident	187 Å²	187	61.3 Å²	61.3	71%	0.706	31%	0.307	S	S	*	.	S	Bend	trans	-81.8	-16.9	-177.6	-69.7	-172.6	173.4	-177.2	-1.9	112.2
40	T	74	Confident	73	Confident	51 Å²	51	61 Å²	61	31%	0.313	31%	0.31	S	S	.	.	S	Bend	trans	-119.7	149.4	-176.6	76	0	0	0	0	112.1	Q38 Q42 E43 F44	Q38-T40 VanDerWaalsContact C-N 3.31Å; T40-Q42 VanDerWaalsContact C-N 3.27Å; T40-Q42 PolarHBondContact O-N 3.19Å; T40-E43 PolarHBondContact O-N 3.39Å; T40-E43 VanDerWaalsContact OG1-CB 3.28Å; T40-E43 WeakPolarHBondContact OG1-CB 3.11Å; T40-E43 PolarHBondContact OG1-N 3.03Å; T40-F44 PolarHBondContact O-N 2.76Å; T40-F44 VanDerWaalsContact O-N 3.14Å
41	T	72.1	Confident	73.1	Confident	3 Å²	3	54.6 Å²	54.6	2%	0.018	29%	0.285	C	S	.	.	H	α-helix	trans	-63.7	-35	176	-49.8	0	0	0	0	111.3	F44 L45 E377 A380	T41-F44 PolarHBondContact O-N 3.43Å; T41-L45 HydrophobicContact CG2-CD1 3.4Å; T41-L45 VanDerWaalsContact CG2-CD1 3.4Å; T41-L45 HydrophobicContact CG2-CG 3.89Å; T41-L45 VanDerWaalsContact O-CB 3.29Å; T41-L45 WeakPolarHBondContact O-CB 3.39Å; T41-L45 WeakPolarHBondContact O-CG 3.49Å; T41-L45 PolarHBondContact O-N 2.91Å; T41-E377 WeakPolarHBondContact CB-OE2 3.24Å; T41-E377 PolarHBondContact N-OE2 3.4Å; T41-E377 PolarHBondContact OG1-OE2 3.45Å; T41-A380 WeakPolarHBondContact OG1-CB 3.46Å
42	Q	75.3	Confident	73.7	Confident	109 Å²	109	60 Å²	60	51%	0.509	31%	0.305	S	S	.	.	H	α-helix	trans	-65.3	-41.5	178	-176.8	174.8	1.1	0	0	111.7	T40 M46 A47	T40-Q42 VanDerWaalsContact C-N 3.27Å; T40-Q42 PolarHBondContact O-N 3.19Å; Q42-M46 HydrophobicContact CG-CB 4.47Å; Q42-M46 CarbonylContact O-C 3.19Å; Q42-M46 VanDerWaalsContact O-CA 3.29Å; Q42-M46 WeakPolarHBondContact O-CA 3.43Å; Q42-M46 VanDerWaalsContact O-CB 3.24Å; Q42-M46 WeakPolarHBondContact O-CB 3.47Å; Q42-M46 PolarHBondContact O-N 3.32Å; Q42-A47 PolarHBondContact O-N 3.25Å
43	E	74.8	Confident	74.5	Confident	31 Å²	31	59.7 Å²	59.7	15%	0.145	30%	0.302	C	S	.	.	H	α-helix	trans	-66.8	-45.8	177.4	-174.3	168.1	-149.9	0	0	111.1	R37 Q38 T40 A47 D48	R37-E43 WeakPolarHBondContact CA-OE1 3.38Å; R37-E43 WeakPolarHBondContact CA-OE2 3.46Å; R37-E43 WeakPolarHBondContact CB-OE1 3.35Å; R37-E43 VanDerWaalsContact CG-OE1 3.24Å; R37-E43 WeakPolarHBondContact CG-OE1 3.46Å; R37-E43 VanDerWaalsContact O-CG 3.29Å; R37-E43 WeakPolarHBondContact O-CG 3.38Å; R37-E43 VanDerWaalsContact O-OE2 3.09Å; Q38-E43 PolarHBondContact N-OE2 2.86Å; T40-E43 PolarHBondContact O-N 3.39Å; T40-E43 VanDerWaalsContact OG1-CB 3.28Å; T40-E43 WeakPolarHBondContact OG1-CB 3.11Å; T40-E43 PolarHBondContact OG1-N 3.03Å; E43-A47 WeakPolarHBondContact O-CA 3.5Å; E43-A47 PolarHBondContact O-N 3.4Å; E43-A47 VanDerWaalsContact O-N 3.09Å; E43-D48 VanDerWaalsContact CA-OD1 3.31Å; E43-D48 WeakPolarHBondContact CA-OD1 2.84Å; E43-D48 WeakPolarHBondContact CB-OD1 3.5Å; E43-D48 WeakPolarHBondContact CG-OD2 3.36Å
44	F	76.2	Confident	75.2	Confident	5 Å²	5	58.1 Å²	58.1	2%	0.022	29%	0.293	C	S	.	.	H	α-helix	trans	-67.4	-42.6	-179.5	-175.2	-103.6	0	0	0	113.2	T40 T41 T177 G180 L181 K385	T40-F44 PolarHBondContact O-N 2.76Å; T40-F44 VanDerWaalsContact O-N 3.14Å; T41-F44 PolarHBondContact O-N 3.43Å; F44-T177 WeakPolarHBondContact CE2-O 3.48Å; F44-G180 VanDerWaalsContact CD2-CA 3.47Å; F44-G180 WeakPolarHBondContact O-CA 3.49Å; F44-L181 PolarHBondContact O-N 3.43Å; F44-K385 HydrophobicContact CE2-CG 4.29Å; F44-K385 HydrophobicContact CZ-CG 4.03Å
45	L	75.8	Confident	76.4	Confident	2 Å²	2	55.5 Å²	55.5	1%	0.01	28%	0.275	C	S	.	.	H	α-helix	trans	-93	-25.3	-175.6	-56.1	-176.6	0	0	0	113.8	T41 L181 Q264 T361	T41-L45 HydrophobicContact CG2-CD1 3.4Å; T41-L45 VanDerWaalsContact CG2-CD1 3.4Å; T41-L45 HydrophobicContact CG2-CG 3.89Å; T41-L45 VanDerWaalsContact O-CB 3.29Å; T41-L45 WeakPolarHBondContact O-CB 3.39Å; T41-L45 WeakPolarHBondContact O-CG 3.49Å; T41-L45 PolarHBondContact O-N 2.91Å; L45-L181 VanDerWaalsContact O-CD2 3.3Å; L45-L181 WeakPolarHBondContact O-CD2 2.99Å; L45-Q264 PolarHBondContact O-NE2 3.07Å; L45-T361 HydrophobicContact CD1-CG2 4.17Å; L45-T361 WeakPolarHBondContact CD2-OG1 3.44Å
46	M	79.7	Confident	78.2	Confident	1 Å²	1	54.6 Å²	54.6	1%	0.005	27%	0.266	C	S	.	.	H	α-helix	trans	-125.2	1.9	-172	-63	-71.7	144.7	0	0	114.4	Q42 D48 R49 S112 Q264 L267 S268 T361	Q42-M46 HydrophobicContact CG-CB 4.47Å; Q42-M46 CarbonylContact O-C 3.19Å; Q42-M46 VanDerWaalsContact O-CA 3.29Å; Q42-M46 WeakPolarHBondContact O-CA 3.43Å; Q42-M46 VanDerWaalsContact O-CB 3.24Å; Q42-M46 WeakPolarHBondContact O-CB 3.47Å; Q42-M46 PolarHBondContact O-N 3.32Å; M46-D48 PolarHBondContact O-N 3.44Å; M46-D48 VanDerWaalsContact O-N 3.14Å; M46-R49 HydrophobicContact CB-CG 4.36Å; M46-R49 PolarHBondContact O-N 3.46Å; M46-S112 WeakPolarHBondContact CE-O 3.08Å; M46-Q264 HydrophobicContact CE-CG 3.85Å; M46-Q264 HydrophobicContact SD-CG 4.34Å; M46-L267 HydrophobicContact SD-CB 4.44Å; M46-S268 WeakPolarHBondContact O-CB 3.21Å; M46-T361 HydrophobicContact CE-CG2 4.02Å
47	A	78.7	Confident	79.9	Confident	0 Å²	0	51.6 Å²	51.6	0%	0	23%	0.234	C	C	.	.	G	3₁₀ helix	trans	52.2	35	-178	0	0	0	0	0	113.2	Q42 E43 R49 S50 M51 L181 K182	Q42-A47 PolarHBondContact O-N 3.25Å; E43-A47 WeakPolarHBondContact O-CA 3.5Å; E43-A47 PolarHBondContact O-N 3.4Å; E43-A47 VanDerWaalsContact O-N 3.09Å; A47-R49 PolarHBondContact O-N 3.04Å; A47-S50 PolarHBondContact O-N 3Å; A47-S50 PolarHBondContact O-OG 2.94Å; A47-M51 HydrophobicContact CB-CG 3.91Å; A47-M51 HydrophobicContact CB-SD 4.15Å; A47-L181 HydrophobicContact CB-CB 4.4Å; A47-L181 HydrophobicContact CB-CD2 4.38Å; A47-L181 HydrophobicContact CB-CG 4.42Å; A47-K182 HydrophobicContact CB-CB 3.77Å; A47-K182 HydrophobicContact CB-CG 4.42Å
48	D	79.1	Confident	81.7	Confident	67 Å²	67	45.3 Å²	45.3	36%	0.358	21%	0.212	S	C	.	.	G	3₁₀ helix	trans	53.7	18	-174.9	-63.6	-37.2	0	0	0	115.5	E43 M46 S50	E43-D48 VanDerWaalsContact CA-OD1 3.31Å; E43-D48 WeakPolarHBondContact CA-OD1 2.84Å; E43-D48 WeakPolarHBondContact CB-OD1 3.5Å; E43-D48 WeakPolarHBondContact CG-OD2 3.36Å; M46-D48 PolarHBondContact O-N 3.44Å; M46-D48 VanDerWaalsContact O-N 3.14Å; D48-S50 PolarHBondContact O-N 3.35Å
49	R	82.2	Confident	83.2	Confident	50 Å²	50	43.9 Å²	43.9	19%	0.189	21%	0.205	C	C	.	.	G	3₁₀ helix	trans	52.3	41	-175.2	-50.1	-169.3	178.5	177.5	2.2	112.4	M46 A47 K110 L111 L267 S268 R270	M46-R49 HydrophobicContact CB-CG 4.36Å; M46-R49 PolarHBondContact O-N 3.46Å; A47-R49 PolarHBondContact O-N 3.04Å; R49-K110 VanDerWaalsContact NH1-CB 3.29Å; R49-K110 VanDerWaalsContact NH2-C 3.3Å; R49-K110 PolarHBondContact NH2-O 3.05Å; R49-L111 PolarHBondContact NH2-O 2.69Å; R49-L267 WeakPolarHBondContact CD-O 3.39Å; R49-L267 VanDerWaalsContact CG-O 3.31Å; R49-L267 WeakPolarHBondContact CG-O 3.46Å; R49-S268 CarbonylContact C-O 3.56Å; R49-S268 WeakPolarHBondContact CA-O 3.28Å; R49-R270 VanDerWaalsContact O-CA 3.23Å; R49-R270 WeakPolarHBondContact O-CA 3.29Å
50	S	85.9	Confident	84.6	Confident	54 Å²	54	35 Å²	35	38%	0.378	17%	0.172	S	C	.	.			trans	-110.8	2.4	-173.4	65	0	0	0	0	113.2	A47 D48 S268	A47-S50 PolarHBondContact O-N 3Å; A47-S50 PolarHBondContact O-OG 2.94Å; D48-S50 PolarHBondContact O-N 3.35Å; S50-S268 PolarHBondContact N-O 3.21Å
51	M	88.9	Confident	85.5	Confident	8 Å²	8	32.6 Å²	32.6	4%	0.039	16%	0.157	C	C	.	.	B	Isolated β-bridge	trans	-77.7	137.3	-170.3	-58.6	-59.3	-74.9	0	0	111.5	A47 P55 V56 K182 I185 S268 A269 R270	A47-M51 HydrophobicContact CB-CG 3.91Å; A47-M51 HydrophobicContact CB-SD 4.15Å; M51-P55 HydrophobicContact CE-CB 4.15Å; M51-V56 HydrophobicContact CB-CG2 3.51Å; M51-K182 HydrophobicContact SD-CG 4.13Å; M51-I185 HydrophobicContact CE-CB 3.7Å; M51-I185 HydrophobicContact CE-CD1 3.81Å; M51-I185 HydrophobicContact CE-CG1 4.36Å; M51-I185 HydrophobicContact CE-CG2 3.3Å; M51-I185 HydrophobicContact CG-CD1 3.86Å; M51-I185 HydrophobicContact SD-CD1 4.49Å; M51-S268 WeakPolarHBondContact CB-O 3.46Å; M51-S268 PolarHBondContact N-O 3.46Å; M51-A269 WeakPolarHBondContact O-CA 3.5Å; M51-R270 PolarHBondContact O-N 3.4Å; M51-R270 VanDerWaalsContact O-N 3.14Å
52	R	91.3	Very high	86.4	Confident	187 Å²	187	32.4 Å²	32.4	71%	0.706	16%	0.156	S	C	*	.			trans	-79.8	161	176.2	-66.2	-176.3	-179.1	-175.6	-0.3	111	L54 P55 V56	R52-L54 PolarHBondContact O-N 3.47Å; R52-P55 WeakPolarHBondContact O-CD 3.44Å; R52-V56 VanDerWaalsContact O-CG2 3.29Å; R52-V56 WeakPolarHBondContact O-CG2 3.23Å; R52-V56 PolarHBondContact O-N 3.02Å
53	C	91.5	Very high	86.9	Confident	11 Å²	11	27.3 Å²	27.3	7%	0.074	13%	0.133	C	C	.	.	H	α-helix	trans	-52.6	-44	-177.4	-168.6	0	0	0	0	115.2	S57 E274 K277 S278 M281	C53-S57 WeakPolarHBondContact O-CB 3.43Å; C53-S57 PolarHBondContact O-N 2.78Å; C53-S57 PolarHBondContact O-OG 3.35Å; C53-E274 HydrophobicContact CB-CB 4.3Å; C53-E274 HydrophobicContact CB-CG 4.24Å; C53-E274 PolarHBondContact N-OE1 3.28Å; C53-K277 VanDerWaalsContact SG-C 3.54Å; C53-K277 VanDerWaalsContact SG-CB 3.55Å; C53-K277 WeakPolarHBondContact SG-CG 3.42Å; C53-S278 PolarHBondContact SG-N 3.07Å; C53-M281 HydrophobicContact CB-CE 4.18Å; C53-M281 WeakPolarHBondContact O-CE 3.38Å; C53-M281 WeakPolarHBondContact SG-CE 3.42Å
54	L	92.5	Very high	87.1	Confident	106 Å²	106	27 Å²	27	56%	0.555	13%	0.131	S	C	*	.	H	α-helix	trans	-69.4	-53.8	-174.6	178	69.8	0	0	0	113.2	R52 V56 S57 L58 M281	R52-L54 PolarHBondContact O-N 3.47Å; L54-V56 VanDerWaalsContact C-N 3.25Å; L54-V56 PolarHBondContact O-N 3.36Å; L54-S57 PolarHBondContact O-N 3.44Å; L54-S57 VanDerWaalsContact O-N 3.11Å; L54-S57 PolarHBondContact O-OG 3.12Å; L54-L58 HydrophobicContact CD1-CD1 4.13Å; L54-L58 HydrophobicContact CD1-CG 4.24Å; L54-L58 HydrophobicContact CG-CD1 4.21Å; L54-L58 PolarHBondContact O-N 2.93Å; L54-M281 HydrophobicContact CB-CE 4.37Å; L54-M281 HydrophobicContact CD1-CE 4.41Å
55	P	92.6	Very high	87.6	Confident	15 Å²	15	27.6 Å²	27.6	10%	0.097	13%	0.133	C	C	.	.	H	α-helix	trans	-55	-41	174.7	-27.2	34	0	0	0	113.1	M51 R52 S59 I185 W186 V189	M51-P55 HydrophobicContact CE-CB 4.15Å; R52-P55 WeakPolarHBondContact O-CD 3.44Å; P55-S59 WeakPolarHBondContact O-CB 3.34Å; P55-S59 PolarHBondContact O-N 3.39Å; P55-I185 HydrophobicContact CB-CG2 3.68Å; P55-I185 WeakPolarHBondContact O-CG2 3.48Å; P55-W186 HydrophobicContact CG-CH2 4.22Å; P55-W186 HydrophobicContact CG-CZ2 4.29Å; P55-V189 HydrophobicContact CB-CG2 4.11Å
56	V	93.1	Very high	88.3	Confident	0 Å²	0	27.6 Å²	27.6	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-61.3	-47.4	176.8	177.2	0	0	0	0	110.5	M51 R52 L54 S59 L60 R265 S278	M51-V56 HydrophobicContact CB-CG2 3.51Å; R52-V56 VanDerWaalsContact O-CG2 3.29Å; R52-V56 WeakPolarHBondContact O-CG2 3.23Å; R52-V56 PolarHBondContact O-N 3.02Å; L54-V56 VanDerWaalsContact C-N 3.25Å; L54-V56 PolarHBondContact O-N 3.36Å; V56-S59 PolarHBondContact O-N 2.84Å; V56-L60 HydrophobicContact CG1-CD1 3.87Å; V56-L60 HydrophobicContact CG1-CG 4.26Å; V56-L60 WeakPolarHBondContact O-CG 3.32Å; V56-L60 PolarHBondContact O-N 3.35Å; V56-R265 HydrophobicContact CG1-CB 4.33Å; V56-S278 WeakPolarHBondContact CG1-OG 3.27Å
57	S	93.8	Very high	88.9	Confident	4 Å²	4	27.6 Å²	27.6	3%	0.028	13%	0.134	C	C	.	.	H	α-helix	trans	-61	-46.3	179.2	67.8	0	0	0	0	113.9	C53 L54 S59 L60 I61 S278 M281	C53-S57 WeakPolarHBondContact O-CB 3.43Å; C53-S57 PolarHBondContact O-N 2.78Å; C53-S57 PolarHBondContact O-OG 3.35Å; L54-S57 PolarHBondContact O-N 3.44Å; L54-S57 VanDerWaalsContact O-N 3.11Å; L54-S57 PolarHBondContact O-OG 3.12Å; S57-S59 VanDerWaalsContact C-N 3.29Å; S57-S59 PolarHBondContact O-N 3.46Å; S57-L60 WeakPolarHBondContact O-CB 3.46Å; S57-L60 PolarHBondContact O-N 2.93Å; S57-I61 VanDerWaalsContact O-CD1 3.29Å; S57-I61 WeakPolarHBondContact O-CD1 3.42Å; S57-I61 VanDerWaalsContact O-CG1 3.32Å; S57-I61 WeakPolarHBondContact O-CG1 3.49Å; S57-I61 PolarHBondContact O-N 3.08Å; S57-S278 WeakPolarHBondContact CB-O 3.25Å; S57-M281 WeakPolarHBondContact OG-CE 3.24Å
58	L	93.2	Very high	89.5	Confident	30 Å²	30	27.7 Å²	27.7	16%	0.157	13%	0.134	C	C	.	.	H	α-helix	trans	-64.1	-38.6	178.5	-68.7	174.7	0	0	0	110.8	L54 I61 A62 V189 T192	L54-L58 HydrophobicContact CD1-CD1 4.13Å; L54-L58 HydrophobicContact CD1-CG 4.24Å; L54-L58 HydrophobicContact CG-CD1 4.21Å; L54-L58 PolarHBondContact O-N 2.93Å; L58-I61 HydrophobicContact CD2-CD1 4.33Å; L58-I61 WeakPolarHBondContact O-CB 3.41Å; L58-I61 PolarHBondContact O-N 3.32Å; L58-A62 WeakPolarHBondContact O-CB 3.34Å; L58-A62 PolarHBondContact O-N 3.19Å; L58-V189 HydrophobicContact CB-CG2 4Å; L58-V189 HydrophobicContact CD1-CB 4.4Å; L58-V189 HydrophobicContact CD1-CG1 3.91Å; L58-V189 HydrophobicContact CD1-CG2 4.08Å; L58-T192 HydrophobicContact CD2-CG2 4.02Å; L58-T192 PolarHBondContact O-OG1 3.45Å
59	S	93.7	Very high	90.1	Very high	0 Å²	0	25.2 Å²	25.2	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-69	-37.1	175.9	-177.5	0	0	0	0	113.4	P55 V56 S57 I61 A62 S63 D188 R265	P55-S59 WeakPolarHBondContact O-CB 3.34Å; P55-S59 PolarHBondContact O-N 3.39Å; V56-S59 PolarHBondContact O-N 2.84Å; S57-S59 VanDerWaalsContact C-N 3.29Å; S57-S59 PolarHBondContact O-N 3.46Å; S59-I61 VanDerWaalsContact C-N 3.32Å; S59-I61 PolarHBondContact O-N 2.92Å; S59-A62 PolarHBondContact O-N 2.82Å; S59-S63 WeakPolarHBondContact O-CB 3.32Å; S59-S63 PolarHBondContact O-N 3.05Å; S59-S63 PolarHBondContact O-OG 3.43Å; S59-D188 WeakPolarHBondContact CB-OD2 3.28Å; S59-D188 PolarHBondContact OG-OD2 2.76Å; S59-R265 PolarHBondContact O-NE 3.27Å; S59-R265 PolarHBondContact OG-NE 3.43Å; S59-R265 PolarHBondContact OG-NH2 3.38Å
60	L	93.1	Very high	90.6	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-61.3	-40.2	171.3	-68.6	162.1	0	0	0	111.5	V56 S57 Q262 R265 Y266 V282	V56-L60 HydrophobicContact CG1-CD1 3.87Å; V56-L60 HydrophobicContact CG1-CG 4.26Å; V56-L60 WeakPolarHBondContact O-CG 3.32Å; V56-L60 PolarHBondContact O-N 3.35Å; S57-L60 WeakPolarHBondContact O-CB 3.46Å; S57-L60 PolarHBondContact O-N 2.93Å; L60-Q262 HydrophobicContact CD2-CB 4.14Å; L60-Q262 HydrophobicContact CD2-CG 4.49Å; L60-Q262 PolarHBondContact O-OE1 2.82Å; L60-R265 HydrophobicContact CD2-CB 3.62Å; L60-R265 HydrophobicContact CD2-CG 4.35Å; L60-R265 HydrophobicContact CG-CB 4.2Å; L60-Y266 HydrophobicContact CD1-CD1 3.85Å; L60-Y266 HydrophobicContact CD1-CE1 3.26Å; L60-Y266 HydrophobicContact CD2-CD1 4.05Å; L60-Y266 HydrophobicContact CD2-CE1 3.56Å; L60-Y266 HydrophobicContact CD2-CE2 4.35Å; L60-Y266 HydrophobicContact CG-CE1 4.09Å; L60-V282 HydrophobicContact CB-CG2 3.67Å; L60-V282 HydrophobicContact CD1-CG2 3.89Å; L60-V282 HydrophobicContact CG-CG2 4.45Å
61	I	91.5	Very high	90.9	Very high	1 Å²	1	20.3 Å²	20.3	1%	0.005	10%	0.096	C	C	.	.	H	α-helix	trans	-65.4	-53.3	174.8	-64.2	150.8	0	0	0	110.1	S57 L58 S59 S63 F64 Q65 T192 V282 S285	S57-I61 VanDerWaalsContact O-CD1 3.29Å; S57-I61 WeakPolarHBondContact O-CD1 3.42Å; S57-I61 VanDerWaalsContact O-CG1 3.32Å; S57-I61 WeakPolarHBondContact O-CG1 3.49Å; S57-I61 PolarHBondContact O-N 3.08Å; L58-I61 HydrophobicContact CD2-CD1 4.33Å; L58-I61 WeakPolarHBondContact O-CB 3.41Å; L58-I61 PolarHBondContact O-N 3.32Å; S59-I61 VanDerWaalsContact C-N 3.32Å; S59-I61 PolarHBondContact O-N 2.92Å; I61-S63 PolarHBondContact O-N 3.46Å; I61-S63 VanDerWaalsContact O-N 3.17Å; I61-F64 PolarHBondContact O-N 2.68Å; I61-F64 VanDerWaalsContact O-N 3.15Å; I61-Q65 HydrophobicContact CG2-CB 4.34Å; I61-Q65 VanDerWaalsContact O-CB 3.29Å; I61-Q65 WeakPolarHBondContact O-CB 3.47Å; I61-Q65 PolarHBondContact O-N 3.45Å; I61-T192 HydrophobicContact CG2-CG2 4.49Å; I61-V282 HydrophobicContact CG1-CB 4.29Å; I61-V282 HydrophobicContact CG1-CG1 3.97Å; I61-V282 HydrophobicContact CG1-CG2 4.16Å; I61-S285 VanDerWaalsContact CD1-OG 3.3Å; I61-S285 WeakPolarHBondContact CD1-OG 3.48Å
62	A	90.7	Very high	91	Very high	0 Å²	0	19.9 Å²	19.9	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-57.4	-33	-177.8	0	0	0	0	0	113.2	L58 S59 F64 D188 T192 S350	L58-A62 WeakPolarHBondContact O-CB 3.34Å; L58-A62 PolarHBondContact O-N 3.19Å; S59-A62 PolarHBondContact O-N 2.82Å; A62-F64 VanDerWaalsContact C-N 3.27Å; A62-F64 PolarHBondContact O-N 2.8Å; A62-D188 HydrophobicContact CB-CB 3.67Å; A62-T192 WeakPolarHBondContact CB-OG1 3.47Å; A62-S350 WeakPolarHBondContact O-CB 3.2Å; A62-S350 PolarHBondContact O-OG 3.49Å
63	S	86.4	Confident	91.1	Very high	2 Å²	2	11.4 Å²	11.4	1%	0.014	6%	0.063	C	C	.	.	H	α-helix	trans	-64.9	-28.9	-178.6	-60.8	0	0	0	0	113.9	S59 I61 R265 T351 S354	S59-S63 WeakPolarHBondContact O-CB 3.32Å; S59-S63 PolarHBondContact O-N 3.05Å; S59-S63 PolarHBondContact O-OG 3.43Å; I61-S63 PolarHBondContact O-N 3.46Å; I61-S63 VanDerWaalsContact O-N 3.17Å; S63-R265 PolarHBondContact OG-NE 3.42Å; S63-R265 VanDerWaalsContact OG-NE 3.15Å; S63-R265 PolarHBondContact OG-NH1 2.97Å; S63-R265 VanDerWaalsContact OG-NH1 3.13Å; S63-R265 PolarHBondContact OG-NH2 2.95Å; S63-T351 WeakPolarHBondContact O-CG2 3.44Å; S63-T351 PolarHBondContact O-OG1 2.69Å; S63-S354 PolarHBondContact OG-OG 3.33Å
64	F	80	Confident	91.2	Very high	24 Å²	24	10.9 Å²	10.9	11%	0.105	6%	0.06	C	C	.	.	H	α-helix	trans	-124	-9.7	-175	-82.8	-69.3	0	0	0	114.3	I61 A62 S66 Y141 L255 Q262 F417	I61-F64 PolarHBondContact O-N 2.68Å; I61-F64 VanDerWaalsContact O-N 3.15Å; A62-F64 VanDerWaalsContact C-N 3.27Å; A62-F64 PolarHBondContact O-N 2.8Å; F64-S66 PolarHBondContact O-N 3.26Å; F64-Y141 HydrophobicContact CE1-CE1 4.36Å; F64-L255 HydrophobicContact CD1-CD2 3.86Å; F64-L255 HydrophobicContact CE1-CD2 3.45Å; F64-L255 VanDerWaalsContact CE1-CD2 3.45Å; F64-L255 HydrophobicContact CZ-CD2 3.9Å; F64-Q262 HydrophobicContact CD2-CG 3.88Å; F64-Q262 HydrophobicContact CE2-CG 3.56Å; F64-Q262 VanDerWaalsContact CE2-NE2 3.25Å; F64-F417 HydrophobicContact CD1-CZ 4.44Å; F64-F417 AromaticContact CE1-CE1 3.94Å; F64-F417 HydrophobicContact CE1-CE1 3.94Å; F64-F417 HydrophobicContact CE1-CE2 4.31Å; F64-F417 AromaticContact CE1-CZ 3.57Å; F64-F417 HydrophobicContact CE1-CZ 3.57Å; F64-F417 HydrophobicContact CZ-CE1 4.43Å; F64-F417 HydrophobicContact CZ-CZ 4.41Å
65	Q	85.7	Confident	91.1	Very high	17 Å²	17	5.9 Å²	5.9	8%	0.079	3%	0.034	C	C	.	.	S	Bend	trans	-80.2	74.9	161.1	-173.9	67.1	-11.9	0	0	108.8	I61 M195 A347	I61-Q65 HydrophobicContact CG2-CB 4.34Å; I61-Q65 VanDerWaalsContact O-CB 3.29Å; I61-Q65 WeakPolarHBondContact O-CB 3.47Å; I61-Q65 PolarHBondContact O-N 3.45Å; Q65-M195 HydrophobicContact CB-CE 3.57Å; Q65-M195 HydrophobicContact CG-CE 3.26Å; Q65-M195 WeakPolarHBondContact O-CE 3.09Å; Q65-A347 WeakPolarHBondContact O-CB 3.39Å
66	S	90.6	Very high	90.9	Very high	3 Å²	3	5.4 Å²	5.4	2%	0.021	3%	0.03	C	C	.	.			trans	-86.2	166.9	-177	66	0	0	0	0	112.2	F64 V68 A69 I70 Y141 T351	F64-S66 PolarHBondContact O-N 3.26Å; S66-V68 PolarHBondContact O-N 3.14Å; S66-V68 VanDerWaalsContact O-N 3.1Å; S66-V68 WeakPolarHBondContact OG-CB 3.26Å; S66-V68 PolarHBondContact OG-N 3.23Å; S66-A69 PolarHBondContact O-N 3.02Å; S66-I70 PolarHBondContact O-N 2.88Å; S66-I70 VanDerWaalsContact O-N 3.15Å; S66-Y141 PolarHBondContact OG-OH 2.77Å; S66-T351 VanDerWaalsContact CB-OG1 3.29Å; S66-T351 WeakPolarHBondContact CB-OG1 3.42Å
67	A	91.9	Very high	90.8	Very high	0 Å²	0	5.4 Å²	5.4	0%	0	3%	0.03	C	C	.	.	H	α-helix	trans	-54.4	-29.5	171.4	0	0	0	0	0	112.2	A69 I70 I71 T148 L344 A347 A348	A67-A69 VanDerWaalsContact C-N 3.34Å; A67-A69 PolarHBondContact O-N 3.43Å; A67-I70 PolarHBondContact O-N 3.17Å; A67-I71 PolarHBondContact O-N 3.35Å; A67-T148 HydrophobicContact CB-CG2 3.81Å; A67-L344 HydrophobicContact CB-CD2 4.44Å; A67-A347 HydrophobicContact CB-CB 4.47Å; A67-A348 HydrophobicContact CB-CB 4.18Å
68	V	91	Very high	90.5	Very high	2 Å²	2	6.5 Å²	6.5	1%	0.012	3%	0.034	C	C	.	.	H	α-helix	trans	-59.7	-42.9	174.3	-178.4	0	0	0	0	111.2	S66 G72 V144 T148 V409 L410 A413	S66-V68 PolarHBondContact O-N 3.14Å; S66-V68 VanDerWaalsContact O-N 3.1Å; S66-V68 WeakPolarHBondContact OG-CB 3.26Å; S66-V68 PolarHBondContact OG-N 3.23Å; V68-G72 VanDerWaalsContact O-CA 3.32Å; V68-G72 WeakPolarHBondContact O-CA 3.41Å; V68-G72 PolarHBondContact O-N 3.44Å; V68-V144 HydrophobicContact CG2-CG1 3.88Å; V68-T148 HydrophobicContact CG2-CG2 4.43Å; V68-T148 WeakPolarHBondContact CG2-OG1 3.26Å; V68-V409 HydrophobicContact CB-CG2 4.46Å; V68-V409 VanDerWaalsContact CG1-C 3.49Å; V68-V409 HydrophobicContact CG1-CB 4.07Å; V68-V409 HydrophobicContact CG1-CG2 3.92Å; V68-V409 WeakPolarHBondContact CG1-O 3.45Å; V68-L410 HydrophobicContact CG1-CB 4.31Å; V68-A413 HydrophobicContact CG1-CB 3.89Å
69	A	92.3	Very high	89.9	Confident	15 Å²	15	6 Å²	6	12%	0.124	3%	0.033	C	C	.	.	H	α-helix	trans	-72.6	-42.8	178.1	0	0	0	0	0	111.7	S66 A67 I71 V73	S66-A69 PolarHBondContact O-N 3.02Å; A67-A69 VanDerWaalsContact C-N 3.34Å; A67-A69 PolarHBondContact O-N 3.43Å; A69-I71 VanDerWaalsContact C-N 3.28Å; A69-I71 PolarHBondContact O-N 3.1Å; A69-V73 WeakPolarHBondContact O-CB 3.1Å; A69-V73 WeakPolarHBondContact O-CG2 3.41Å; A69-V73 PolarHBondContact O-N 3.24Å; A69-V73 VanDerWaalsContact O-N 3.08Å
70	I	93.3	Very high	89.3	Confident	0 Å²	0	7 Å²	7	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-62.2	-34.3	-178.5	-62.9	-178.2	0	0	0	112	S66 A67 P74 M195 Q199 M296 F340 L344 A347	S66-I70 PolarHBondContact O-N 2.88Å; S66-I70 VanDerWaalsContact O-N 3.15Å; A67-I70 PolarHBondContact O-N 3.17Å; I70-P74 WeakPolarHBondContact O-CD 3.44Å; I70-P74 VanDerWaalsContact O-CG 3.25Å; I70-P74 WeakPolarHBondContact O-CG 3.34Å; I70-M195 HydrophobicContact CD1-CB 4.41Å; I70-M195 HydrophobicContact CD1-CE 4.29Å; I70-M195 HydrophobicContact CD1-CG 4.34Å; I70-Q199 HydrophobicContact CG2-CG 4.2Å; I70-M296 WeakPolarHBondContact O-CE 3.17Å; I70-F340 HydrophobicContact CG2-CE2 4.35Å; I70-L344 HydrophobicContact CB-CD2 3.97Å; I70-L344 HydrophobicContact CG2-CD2 3.56Å; I70-A347 HydrophobicContact CD1-CB 3.59Å
71	I	92.1	Very high	89	Confident	1 Å²	1	7 Å²	7	1%	0.005	4%	0.038	C	C	.	.	H	α-helix	trans	-91.7	-47.3	176.2	-67.9	167.6	0	0	0	111.1	A67 A69 P74 A75 T148 A152 D319 V322 I323 L344	A67-I71 PolarHBondContact O-N 3.35Å; A69-I71 VanDerWaalsContact C-N 3.28Å; A69-I71 PolarHBondContact O-N 3.1Å; I71-P74 WeakPolarHBondContact O-CD 3.34Å; I71-A75 WeakPolarHBondContact O-CB 3.37Å; I71-A75 PolarHBondContact O-N 3.04Å; I71-T148 HydrophobicContact CD1-CG2 3.76Å; I71-A152 HydrophobicContact CD1-CB 3.95Å; I71-D319 HydrophobicContact CG2-CB 3.71Å; I71-V322 HydrophobicContact CG2-CB 4.24Å; I71-V322 HydrophobicContact CG2-CG2 4.38Å; I71-V322 WeakPolarHBondContact O-CG2 3.48Å; I71-I323 HydrophobicContact CD1-CD1 3.83Å; I71-I323 HydrophobicContact CG1-CD1 4.12Å; I71-L344 HydrophobicContact CD1-CD1 3.92Å; I71-L344 HydrophobicContact CD1-CD2 3.84Å; I71-L344 HydrophobicContact CG1-CD1 4.41Å; I71-L344 HydrophobicContact CG1-CD2 3.74Å
72	G	90.9	Very high	88.9	Confident	0 Å²	0	7.9 Å²	7.9	0%	0	4%	0.043	C	C	.	.	H	α-helix	trans	-74.3	-33.3	-168.1	0	0	0	0	0	114.5	V68 A75 E76	V68-G72 VanDerWaalsContact O-CA 3.32Å; V68-G72 WeakPolarHBondContact O-CA 3.41Å; V68-G72 PolarHBondContact O-N 3.44Å; G72-A75 PolarHBondContact O-N 3.44Å; G72-E76 VanDerWaalsContact O-CB 3.31Å; G72-E76 WeakPolarHBondContact O-CB 3.28Å; G72-E76 PolarHBondContact O-N 3.18Å
73	V	92.9	Very high	88.9	Confident	8 Å²	8	10.3 Å²	10.3	5%	0.048	5%	0.054	C	C	.	.	H	α-helix	trans	-68	-48.6	179.2	176.3	0	0	0	0	111.6	A69 A75 E76 I77 Y84 L290 L410	A69-V73 WeakPolarHBondContact O-CB 3.1Å; A69-V73 WeakPolarHBondContact O-CG2 3.41Å; A69-V73 PolarHBondContact O-N 3.24Å; A69-V73 VanDerWaalsContact O-N 3.08Å; V73-A75 VanDerWaalsContact C-N 3.32Å; V73-A75 PolarHBondContact O-N 3.24Å; V73-E76 WeakPolarHBondContact O-CB 3.33Å; V73-E76 PolarHBondContact O-N 3.1Å; V73-E76 VanDerWaalsContact O-N 3.16Å; V73-I77 HydrophobicContact CG1-CG1 4.32Å; V73-I77 VanDerWaalsContact O-CG1 3.23Å; V73-I77 WeakPolarHBondContact O-CG1 3.4Å; V73-I77 PolarHBondContact O-N 2.9Å; V73-Y84 HydrophobicContact CB-CE1 4.43Å; V73-Y84 HydrophobicContact CG1-CD1 3.84Å; V73-Y84 HydrophobicContact CG1-CE1 3.94Å; V73-Y84 HydrophobicContact CG2-CD1 4.37Å; V73-Y84 HydrophobicContact CG2-CE1 3.68Å; V73-L290 HydrophobicContact CG1-CD1 4.23Å; V73-L410 HydrophobicContact CG2-CD1 4.37Å; V73-L410 HydrophobicContact CG2-CD2 3.95Å
74	P	93.8	Very high	89.1	Confident	0 Å²	0	10.7 Å²	10.7	0%	0	6%	0.055	C	C	.	.	H	α-helix	trans	-59.3	-40.5	173.5	-21.7	30.5	0	0	0	113.2	I70 I71 E76 I77 Y78 M296 G297 M300 V322	I70-P74 WeakPolarHBondContact O-CD 3.44Å; I70-P74 VanDerWaalsContact O-CG 3.25Å; I70-P74 WeakPolarHBondContact O-CG 3.34Å; I71-P74 WeakPolarHBondContact O-CD 3.34Å; P74-E76 VanDerWaalsContact C-N 3.29Å; P74-E76 PolarHBondContact O-N 3.46Å; P74-I77 PolarHBondContact O-N 3.47Å; P74-Y78 VanDerWaalsContact O-CB 3.28Å; P74-Y78 WeakPolarHBondContact O-CB 3.32Å; P74-Y78 PolarHBondContact O-N 3.24Å; P74-M296 HydrophobicContact CB-CB 4.32Å; P74-M296 HydrophobicContact CB-CE 3.87Å; P74-M296 HydrophobicContact CB-CG 4.3Å; P74-M296 HydrophobicContact CG-CB 4.32Å; P74-M296 HydrophobicContact CG-CE 3.18Å; P74-M296 HydrophobicContact CG-CG 4.44Å; P74-G297 WeakPolarHBondContact O-CA 3.29Å; P74-M300 HydrophobicContact CB-SD 4.01Å; P74-V322 HydrophobicContact CB-CG2 4.22Å
75	A	90	Very high	89.6	Confident	2 Å²	2	14.6 Å²	14.6	2%	0.017	7%	0.069	C	C	.	.	H	α-helix	trans	-60.5	-40.3	175.2	0	0	0	0	0	111.7	I71 G72 V73 T79 R318 V322	I71-A75 WeakPolarHBondContact O-CB 3.37Å; I71-A75 PolarHBondContact O-N 3.04Å; G72-A75 PolarHBondContact O-N 3.44Å; V73-A75 VanDerWaalsContact C-N 3.32Å; V73-A75 PolarHBondContact O-N 3.24Å; A75-T79 WeakPolarHBondContact O-CB 3.18Å; A75-T79 WeakPolarHBondContact O-CG2 3.28Å; A75-T79 PolarHBondContact O-N 3.44Å; A75-T79 VanDerWaalsContact O-N 3.09Å; A75-T79 PolarHBondContact O-OG1 2.89Å; A75-R318 WeakPolarHBondContact CB-O 3.3Å; A75-V322 HydrophobicContact CB-CG2 3.75Å
76	E	88.4	Confident	89.9	Confident	5 Å²	5	15.5 Å²	15.5	2%	0.023	7%	0.073	C	C	.	.	H	α-helix	trans	-63.3	-47.3	175.9	179.7	60.2	-171.4	0	0	111.9	G72 V73 P74 T79 H80 Y84 R238 H239 L410	G72-E76 VanDerWaalsContact O-CB 3.31Å; G72-E76 WeakPolarHBondContact O-CB 3.28Å; G72-E76 PolarHBondContact O-N 3.18Å; V73-E76 WeakPolarHBondContact O-CB 3.33Å; V73-E76 PolarHBondContact O-N 3.1Å; V73-E76 VanDerWaalsContact O-N 3.16Å; P74-E76 VanDerWaalsContact C-N 3.29Å; P74-E76 PolarHBondContact O-N 3.46Å; E76-T79 PolarHBondContact O-N 3.5Å; E76-T79 PolarHBondContact O-OG1 3.35Å; E76-T79 VanDerWaalsContact O-OG1 3.1Å; E76-H80 PolarHBondContact O-N 2.95Å; E76-H80 IonicContact OE1-CG 3.94Å; E76-H80 IonicContact OE1-ND1 3.88Å; E76-H80 PolarHBondContact OE1-ND1 3.46Å; E76-H80 IonicContact OE2-CE1 3.87Å; E76-H80 IonicContact OE2-ND1 3.99Å; E76-H80 PolarHBondContact OE2-ND1 3.4Å; E76-Y84 HydrophobicContact CG-CD2 4.42Å; E76-Y84 HydrophobicContact CG-CG 4.4Å; E76-R238 IonicContact OE1-CZ 3.32Å; E76-R238 IonicContact OE1-NE 3.14Å; E76-R238 PolarHBondContact OE1-NE 3.21Å; E76-R238 VanDerWaalsContact OE1-NE 3.07Å; E76-R238 IonicContact OE1-NH1 3.91Å; E76-R238 IonicContact OE1-NH2 3.78Å; E76-R238 PolarHBondContact OE1-NH2 2.85Å; E76-R238 IonicContact OE2-CZ 3.79Å; E76-R238 IonicContact OE2-NH1 2.77Å; E76-R238 IonicContact OE2-NH2 3.44Å; E76-R238 PolarHBondContact OE2-NH2 3.27Å; E76-H239 IonicContact OE1-CE1 2.79Å; E76-H239 PolarHBondContact OE1-CE1 3.35Å; E76-H239 IonicContact OE1-ND1 3.5Å; E76-H239 PolarHBondContact OE1-ND1 2.89Å; E76-L410 HydrophobicContact CB-CD2 4.35Å
77	I	90.9	Very high	90	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-66.7	-40.7	-179.6	-60.7	-74.9	0	0	0	111	V73 P74 T79 G81 T82 C294 L298	V73-I77 HydrophobicContact CG1-CG1 4.32Å; V73-I77 VanDerWaalsContact O-CG1 3.23Å; V73-I77 WeakPolarHBondContact O-CG1 3.4Å; V73-I77 PolarHBondContact O-N 2.9Å; P74-I77 PolarHBondContact O-N 3.47Å; I77-T79 VanDerWaalsContact C-N 3.3Å; I77-T79 PolarHBondContact O-N 2.95Å; I77-G81 WeakPolarHBondContact CA-O 3.27Å; I77-G81 WeakPolarHBondContact CD1-O 3.04Å; I77-G81 VanDerWaalsContact O-CA 3.24Å; I77-G81 WeakPolarHBondContact O-CA 3.41Å; I77-G81 PolarHBondContact O-N 3.33Å; I77-T82 HydrophobicContact CG2-CG2 4.43Å; I77-C294 HydrophobicContact CD1-CB 4.43Å; I77-L298 HydrophobicContact CG2-CD2 4.17Å; I77-L298 HydrophobicContact CG2-CG 4.13Å
78	Y	87.6	Confident	90	Very high	26 Å²	26	15.6 Å²	15.6	10%	0.102	7%	0.074	C	C	.	.	H	α-helix	trans	-58.1	-42.9	174.3	170.4	-108.4	0	0	0	111.8	P74 R225 M300 F301 M321	P74-Y78 VanDerWaalsContact O-CB 3.28Å; P74-Y78 WeakPolarHBondContact O-CB 3.32Å; P74-Y78 PolarHBondContact O-N 3.24Å; Y78-R225 PolarHBondContact O-NH1 3.28Å; Y78-M300 HydrophobicContact CD2-CB 3.94Å; Y78-M300 HydrophobicContact CG-CB 4.45Å; Y78-M300 HydrophobicContact CG-CE 4.31Å; Y78-F301 HydrophobicContact CD2-CB 4.01Å; Y78-M321 HydrophobicContact CD1-CG 4.27Å; Y78-M321 HydrophobicContact CE1-CG 3.83Å
79	T	81.8	Confident	90.1	Very high	21 Å²	21	18.1 Å²	18.1	13%	0.129	9%	0.091	C	C	.	.	H	α-helix	trans	-84.1	-39.7	-174.1	47.7	0	0	0	0	113.9	A75 E76 I77 R225 R318	A75-T79 WeakPolarHBondContact O-CB 3.18Å; A75-T79 WeakPolarHBondContact O-CG2 3.28Å; A75-T79 PolarHBondContact O-N 3.44Å; A75-T79 VanDerWaalsContact O-N 3.09Å; A75-T79 PolarHBondContact O-OG1 2.89Å; E76-T79 PolarHBondContact O-N 3.5Å; E76-T79 PolarHBondContact O-OG1 3.35Å; E76-T79 VanDerWaalsContact O-OG1 3.1Å; I77-T79 VanDerWaalsContact C-N 3.3Å; I77-T79 PolarHBondContact O-N 2.95Å; T79-R225 VanDerWaalsContact C-NH1 3.26Å; T79-R225 PolarHBondContact O-NH1 2.86Å; T79-R318 HydrophobicContact CG2-CG 4.27Å
80	H	80.9	Confident	90.2	Very high	20 Å²	20	17.4 Å²	17.4	9%	0.093	9%	0.085	C	C	.	.	H	α-helix	trans	-118.9	-4.9	-170.8	-56	91.1	0	0	0	114.5	E76 R238	E76-H80 PolarHBondContact O-N 2.95Å; E76-H80 IonicContact OE1-CG 3.94Å; E76-H80 IonicContact OE1-ND1 3.88Å; E76-H80 PolarHBondContact OE1-ND1 3.46Å; E76-H80 IonicContact OE2-CE1 3.87Å; E76-H80 IonicContact OE2-ND1 3.99Å; E76-H80 PolarHBondContact OE2-ND1 3.4Å; H80-R238 PolarHBondContact CE1-NH1 3.04Å; H80-R238 VanDerWaalsContact CE1-NH1 3.29Å; H80-R238 PolarHBondContact NE2-NH1 3.28Å
81	G	86.5	Confident	90.2	Very high	1 Å²	1	18.5 Å²	18.5	1%	0.01	9%	0.09	C	C	.	.			trans	88	-169.6	-178.9	0	0	0	0	0	113.6	I77 Q83 R225	I77-G81 WeakPolarHBondContact CA-O 3.27Å; I77-G81 WeakPolarHBondContact CD1-O 3.04Å; I77-G81 VanDerWaalsContact O-CA 3.24Å; I77-G81 WeakPolarHBondContact O-CA 3.41Å; I77-G81 PolarHBondContact O-N 3.33Å; G81-Q83 VanDerWaalsContact C-N 3.25Å; G81-Q83 PolarHBondContact O-N 3.3Å; G81-R225 WeakPolarHBondContact CA-O 3.47Å
82	T	89.8	Confident	90.2	Very high	18 Å²	18	22.7 Å²	22.7	11%	0.11	11%	0.111	C	C	.	.	G	3₁₀ helix	trans	-80.6	10.4	-168.6	61.8	0	0	0	0	115.5	I77 Y84 W85 R225 L226 S227 L298	I77-T82 HydrophobicContact CG2-CG2 4.43Å; T82-Y84 PolarHBondContact O-N 3.3Å; T82-W85 WeakPolarHBondContact O-CB 3.49Å; T82-W85 PolarHBondContact O-N 2.95Å; T82-R225 PolarHBondContact N-O 3.46Å; T82-R225 PolarHBondContact OG1-O 2.94Å; T82-L226 HydrophobicContact CG2-CD2 4.08Å; T82-S227 PolarHBondContact N-OG 2.91Å; T82-S227 PolarHBondContact OG1-N 2.88Å; T82-L298 HydrophobicContact CG2-CD1 3.99Å; T82-L298 HydrophobicContact CG2-CD2 3.68Å; T82-L298 HydrophobicContact CG2-CG 4.1Å
83	Q	89.9	Confident	90.2	Very high	51 Å²	51	26.8 Å²	26.8	24%	0.238	13%	0.133	C	C	.	.	G	3₁₀ helix	trans	-53.1	-42.6	-179.5	-62.8	-176.8	-48.5	0	0	112.1	G81 W85 F86 S227 H239 L244	G81-Q83 VanDerWaalsContact C-N 3.25Å; G81-Q83 PolarHBondContact O-N 3.3Å; Q83-W85 PolarHBondContact O-N 3.25Å; Q83-F86 VanDerWaalsContact O-CD2 3.28Å; Q83-F86 WeakPolarHBondContact O-CD2 3.31Å; Q83-F86 PolarHBondContact O-N 3.44Å; Q83-F86 VanDerWaalsContact O-N 3.15Å; Q83-S227 VanDerWaalsContact CG-CB 3.4Å; Q83-S227 VanDerWaalsContact CG-OG 3.23Å; Q83-S227 WeakPolarHBondContact CG-OG 3.47Å; Q83-S227 PolarHBondContact N-OG 3.48Å; Q83-H239 HydrophobicContact CB-CB 4.01Å; Q83-L244 WeakPolarHBondContact O-CD1 3.39Å
84	Y	90	Very high	90.1	Very high	10 Å²	10	26.4 Å²	26.4	4%	0.039	13%	0.13	C	C	.	.	G	3₁₀ helix	trans	-58.7	-22.1	-178.8	-168.3	-96.9	0	0	0	113.9	V73 E76 T82 F86 I87 H239 L244 L290 L414	V73-Y84 HydrophobicContact CB-CE1 4.43Å; V73-Y84 HydrophobicContact CG1-CD1 3.84Å; V73-Y84 HydrophobicContact CG1-CE1 3.94Å; V73-Y84 HydrophobicContact CG2-CD1 4.37Å; V73-Y84 HydrophobicContact CG2-CE1 3.68Å; E76-Y84 HydrophobicContact CG-CD2 4.42Å; E76-Y84 HydrophobicContact CG-CG 4.4Å; T82-Y84 PolarHBondContact O-N 3.3Å; Y84-F86 PolarHBondContact O-N 3.24Å; Y84-F86 VanDerWaalsContact O-N 3.13Å; Y84-I87 HydrophobicContact CD1-CG2 4.19Å; Y84-I87 HydrophobicContact CE1-CG2 3.9Å; Y84-I87 HydrophobicContact CE2-CD1 4.16Å; Y84-I87 WeakPolarHBondContact O-CB 3.5Å; Y84-I87 WeakPolarHBondContact O-CG2 3.4Å; Y84-I87 PolarHBondContact O-N 3.04Å; Y84-H239 AromaticContact CD2-CE1 3.68Å; Y84-H239 AromaticContact CD2-NE2 3.97Å; Y84-L244 HydrophobicContact CD2-CD2 4.11Å; Y84-L244 HydrophobicContact CE2-CD2 4.46Å; Y84-L290 HydrophobicContact CD1-CD1 3.95Å; Y84-L290 HydrophobicContact CE1-CD1 3.93Å; Y84-L414 HydrophobicContact CE2-CD1 4.25Å
85	W	91.8	Very high	90	Very high	106 Å²	106	26.7 Å²	26.7	40%	0.402	13%	0.132	S	C	.	.	G	3₁₀ helix	trans	-53	-33.3	175.2	177.6	-110.4	0	0	0	113.2	T82 Q83 I87 G88 L290 C294	T82-W85 WeakPolarHBondContact O-CB 3.49Å; T82-W85 PolarHBondContact O-N 2.95Å; Q83-W85 PolarHBondContact O-N 3.25Å; W85-I87 PolarHBondContact O-N 3.49Å; W85-I87 VanDerWaalsContact O-N 3.09Å; W85-G88 PolarHBondContact O-N 3.29Å; W85-L290 HydrophobicContact CE3-CD2 3.93Å; W85-L290 HydrophobicContact CE3-CG 3.8Å; W85-L290 HydrophobicContact CZ3-CB 4.33Å; W85-L290 HydrophobicContact CZ3-CD2 4.12Å; W85-L290 HydrophobicContact CZ3-CG 3.88Å; W85-C294 HydrophobicContact CE3-CB 4.28Å
86	F	91.6	Very high	90.2	Very high	37 Å²	37	29.9 Å²	29.9	16%	0.162	15%	0.148	C	C	.	.	G	3₁₀ helix	trans	-66	-11.1	-179.2	-68.1	-68	0	0	0	114	Q83 Y84 G88 C89 G228 L229 L244	Q83-F86 VanDerWaalsContact O-CD2 3.28Å; Q83-F86 WeakPolarHBondContact O-CD2 3.31Å; Q83-F86 PolarHBondContact O-N 3.44Å; Q83-F86 VanDerWaalsContact O-N 3.15Å; Y84-F86 PolarHBondContact O-N 3.24Å; Y84-F86 VanDerWaalsContact O-N 3.13Å; F86-G88 PolarHBondContact O-N 2.67Å; F86-C89 WeakPolarHBondContact O-CB 3.36Å; F86-C89 PolarHBondContact O-N 2.58Å; F86-C89 VanDerWaalsContact O-N 3.09Å; F86-G228 WeakPolarHBondContact CE2-O 3.44Å; F86-L229 HydrophobicContact CD1-CD1 4.02Å; F86-L229 HydrophobicContact CE1-CD1 3.58Å; F86-L229 HydrophobicContact CZ-CB 4.3Å; F86-L229 HydrophobicContact CZ-CD1 3.93Å; F86-L244 HydrophobicContact CB-CB 4.29Å; F86-L244 HydrophobicContact CB-CD1 4.13Å
87	I	92.2	Very high	90.5	Very high	1 Å²	1	32.2 Å²	32.2	1%	0.005	16%	0.16	C	C	.	.	H	α-helix	trans	-60.3	-24.8	168.9	-157.6	171.8	0	0	0	112.1	Y84 W85 C89 A90 Y91 L244 M252 L290 M506	Y84-I87 HydrophobicContact CD1-CG2 4.19Å; Y84-I87 HydrophobicContact CE1-CG2 3.9Å; Y84-I87 HydrophobicContact CE2-CD1 4.16Å; Y84-I87 WeakPolarHBondContact O-CB 3.5Å; Y84-I87 WeakPolarHBondContact O-CG2 3.4Å; Y84-I87 PolarHBondContact O-N 3.04Å; W85-I87 PolarHBondContact O-N 3.49Å; W85-I87 VanDerWaalsContact O-N 3.09Å; I87-C89 PolarHBondContact O-N 3.46Å; I87-A90 HydrophobicContact CG1-CB 4.49Å; I87-A90 WeakPolarHBondContact O-CA 3.18Å; I87-A90 WeakPolarHBondContact O-CB 3.42Å; I87-A90 PolarHBondContact O-N 2.66Å; I87-Y91 HydrophobicContact CG1-CE1 4.17Å; I87-Y91 HydrophobicContact CG2-CE1 4.33Å; I87-Y91 PolarHBondContact O-N 3.23Å; I87-L244 HydrophobicContact CB-CD2 4.3Å; I87-M252 HydrophobicContact CD1-CE 4.29Å; I87-L290 HydrophobicContact CG2-CD1 3.96Å; I87-L290 HydrophobicContact CG2-CD2 3.68Å; I87-L290 HydrophobicContact CG2-CG 4.5Å; I87-M506 HydrophobicContact CD1-CE 3.85Å; I87-M506 HydrophobicContact CG1-CE 4.31Å
88	G	92.4	Very high	90.7	Very high	4 Å²	4	32.2 Å²	32.2	4%	0.041	16%	0.16	C	C	.	.	H	α-helix	trans	-61.4	-27.6	174.9	0	0	0	0	0	113.5	W85 F86 A90 Y91	W85-G88 PolarHBondContact O-N 3.29Å; F86-G88 PolarHBondContact O-N 2.67Å; G88-A90 VanDerWaalsContact C-N 3.26Å; G88-A90 PolarHBondContact O-N 3.25Å; G88-Y91 WeakPolarHBondContact O-CB 3.39Å; G88-Y91 PolarHBondContact O-N 3.23Å
89	C	92.3	Very high	91	Very high	54 Å²	54	31 Å²	31	37%	0.365	16%	0.155	S	C	.	.	H	α-helix	trans	-63.9	-36	171.1	-62.1	0	0	0	0	111.3	F86 I87 Y91 I92	F86-C89 WeakPolarHBondContact O-CB 3.36Å; F86-C89 PolarHBondContact O-N 2.58Å; F86-C89 VanDerWaalsContact O-N 3.09Å; I87-C89 PolarHBondContact O-N 3.46Å; C89-Y91 VanDerWaalsContact C-N 3.3Å; C89-Y91 PolarHBondContact O-N 2.95Å; C89-I92 WeakPolarHBondContact O-CB 3.15Å; C89-I92 PolarHBondContact O-N 3.21Å
90	A	94.1	Very high	91.5	Very high	0 Å²	0	34.7 Å²	34.7	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-68.6	-29.5	177.7	0	0	0	0	0	112.3	I87 G88 I92 G94 L244 V249	I87-A90 HydrophobicContact CG1-CB 4.49Å; I87-A90 WeakPolarHBondContact O-CA 3.18Å; I87-A90 WeakPolarHBondContact O-CB 3.42Å; I87-A90 PolarHBondContact O-N 2.66Å; G88-A90 VanDerWaalsContact C-N 3.26Å; G88-A90 PolarHBondContact O-N 3.25Å; A90-I92 PolarHBondContact O-N 3.44Å; A90-G94 VanDerWaalsContact O-CA 3.31Å; A90-G94 WeakPolarHBondContact O-CA 3.32Å; A90-G94 PolarHBondContact O-N 3.36Å; A90-L244 WeakPolarHBondContact CB-O 3.05Å; A90-V249 HydrophobicContact CB-CG2 4.06Å
91	Y	93.4	Very high	92	Very high	24 Å²	24	34.3 Å²	34.3	9%	0.094	17%	0.17	C	C	.	.	H	α-helix	trans	-62.2	-30.8	176.9	-62.7	-9.1	0	0	0	112.3	I87 G88 C89 L95 M252 L286 L290	I87-Y91 HydrophobicContact CG1-CE1 4.17Å; I87-Y91 HydrophobicContact CG2-CE1 4.33Å; I87-Y91 PolarHBondContact O-N 3.23Å; G88-Y91 WeakPolarHBondContact O-CB 3.39Å; G88-Y91 PolarHBondContact O-N 3.23Å; C89-Y91 VanDerWaalsContact C-N 3.3Å; C89-Y91 PolarHBondContact O-N 2.95Å; Y91-L95 WeakPolarHBondContact O-CB 3.38Å; Y91-L95 WeakPolarHBondContact O-CG 3.29Å; Y91-L95 PolarHBondContact O-N 3.09Å; Y91-M252 HydrophobicContact CD1-CE 4.21Å; Y91-M252 HydrophobicContact CD1-CG 3.84Å; Y91-M252 HydrophobicContact CD1-SD 3.5Å; Y91-M252 VanDerWaalsContact CD1-SD 3.5Å; Y91-M252 HydrophobicContact CE1-CE 3.67Å; Y91-M252 HydrophobicContact CE1-CG 4.27Å; Y91-M252 HydrophobicContact CE1-SD 3.49Å; Y91-M252 WeakPolarHBondContact CE1-SD 3.41Å; Y91-L286 HydrophobicContact CD2-CB 3.74Å; Y91-L286 HydrophobicContact CD2-CD1 4.28Å; Y91-L286 HydrophobicContact CE2-CB 3.75Å; Y91-L286 HydrophobicContact CE2-CD1 4.48Å; Y91-L286 HydrophobicContact CG-CD1 4.44Å; Y91-L290 HydrophobicContact CE2-CB 4.36Å; Y91-L290 HydrophobicContact CE2-CD2 4.05Å
92	I	91.9	Very high	92.3	Very high	89 Å²	89	34.3 Å²	34.3	46%	0.456	17%	0.17	S	C	.	.	H	α-helix	trans	-59.7	-61.9	179.1	-58.5	172.9	0	0	0	109.6	C89 A90 L96 F283	C89-I92 WeakPolarHBondContact O-CB 3.15Å; C89-I92 PolarHBondContact O-N 3.21Å; A90-I92 PolarHBondContact O-N 3.44Å; I92-L96 WeakPolarHBondContact O-CB 3.44Å; I92-L96 PolarHBondContact O-N 3.36Å; I92-F283 HydrophobicContact CB-CE2 4.37Å; I92-F283 HydrophobicContact CG1-CE2 3.55Å; I92-F283 HydrophobicContact CG1-CZ 3.83Å
93	L	91.6	Very high	92.6	Very high	86 Å²	86	33.7 Å²	33.7	45%	0.45	17%	0.166	S	C	.	.	H	α-helix	trans	-72.2	-34.2	-179.8	-63	-179.7	0	0	0	111.8	L95 L96 I97 V249	L93-L95 PolarHBondContact O-N 3.04Å; L93-L96 HydrophobicContact CD2-CD2 4.4Å; L93-L96 PolarHBondContact O-N 3.42Å; L93-I97 HydrophobicContact CB-CD1 4.3Å; L93-I97 WeakPolarHBondContact O-CB 3.28Å; L93-I97 WeakPolarHBondContact O-CG1 3.47Å; L93-I97 PolarHBondContact O-N 3.25Å; L93-V249 HydrophobicContact CB-CG1 4.26Å; L93-V249 HydrophobicContact CB-CG2 3.83Å; L93-V249 HydrophobicContact CD1-CG2 4.31Å
94	G	91.6	Very high	92.7	Very high	0 Å²	0	32 Å²	32	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-63	-21.3	178.5	0	0	0	0	0	114.6	A90 P98	A90-G94 VanDerWaalsContact O-CA 3.31Å; A90-G94 WeakPolarHBondContact O-CA 3.32Å; A90-G94 PolarHBondContact O-N 3.36Å; G94-P98 WeakPolarHBondContact O-CD 3.24Å; G94-P98 WeakPolarHBondContact O-CG 3.27Å
95	L	92.3	Very high	92.7	Very high	5 Å²	5	32.2 Å²	32.2	3%	0.026	16%	0.161	C	C	.	.	H	α-helix	trans	-107.1	-34.1	172.7	-66.7	173.6	0	0	0	112.8	Y91 L93 I97 P98 A99 Y256 V282 F283 L286	Y91-L95 WeakPolarHBondContact O-CB 3.38Å; Y91-L95 WeakPolarHBondContact O-CG 3.29Å; Y91-L95 PolarHBondContact O-N 3.09Å; L93-L95 PolarHBondContact O-N 3.04Å; L95-I97 PolarHBondContact O-N 3.29Å; L95-P98 WeakPolarHBondContact O-CD 3.39Å; L95-A99 VanDerWaalsContact O-CB 3.23Å; L95-A99 WeakPolarHBondContact O-CB 3.31Å; L95-A99 PolarHBondContact O-N 3.15Å; L95-Y256 HydrophobicContact CD2-CD1 3.92Å; L95-Y256 HydrophobicContact CD2-CD2 3.92Å; L95-Y256 HydrophobicContact CD2-CE1 4.33Å; L95-Y256 HydrophobicContact CD2-CE2 4.33Å; L95-Y256 HydrophobicContact CD2-CG 3.69Å; L95-V282 HydrophobicContact CD1-CB 4.34Å; L95-V282 HydrophobicContact CD1-CG1 4.21Å; L95-V282 HydrophobicContact CD2-CG1 4.31Å; L95-F283 HydrophobicContact CD1-CB 3.66Å; L95-F283 HydrophobicContact CD1-CD2 4.19Å; L95-F283 HydrophobicContact CD1-CG 4.45Å; L95-L286 HydrophobicContact CD1-CD1 4.2Å
96	L	93.8	Very high	92.8	Very high	69 Å²	69	27.4 Å²	27.4	36%	0.361	14%	0.143	S	C	.	.	H	α-helix	trans	-61.8	-43.2	177.9	-175	68.6	0	0	0	112	I92 L93 A99 H100 Y280	I92-L96 WeakPolarHBondContact O-CB 3.44Å; I92-L96 PolarHBondContact O-N 3.36Å; L93-L96 HydrophobicContact CD2-CD2 4.4Å; L93-L96 PolarHBondContact O-N 3.42Å; L96-A99 PolarHBondContact O-N 2.89Å; L96-H100 PolarHBondContact O-N 3.28Å; L96-Y280 HydrophobicContact CD1-CE1 4.11Å; L96-Y280 WeakPolarHBondContact CD1-OH 3.46Å
97	I	94.1	Very high	92.8	Very high	55 Å²	55	27.2 Å²	27.2	28%	0.282	14%	0.141	S	C	.	.	H	α-helix	trans	-66.8	-50.4	-179.8	-66.2	166.7	0	0	0	110.7	L93 L95 A99 H100 V101 F102 V249 L253	L93-I97 HydrophobicContact CB-CD1 4.3Å; L93-I97 WeakPolarHBondContact O-CB 3.28Å; L93-I97 WeakPolarHBondContact O-CG1 3.47Å; L93-I97 PolarHBondContact O-N 3.25Å; L95-I97 PolarHBondContact O-N 3.29Å; I97-A99 VanDerWaalsContact C-N 3.32Å; I97-A99 PolarHBondContact O-N 2.81Å; I97-H100 PolarHBondContact O-N 3.01Å; I97-V101 HydrophobicContact CG2-CB 4.49Å; I97-V101 HydrophobicContact CG2-CG2 4.35Å; I97-V101 VanDerWaalsContact O-CB 3.29Å; I97-V101 WeakPolarHBondContact O-CB 3.25Å; I97-V101 PolarHBondContact O-N 3.41Å; I97-F102 HydrophobicContact CG2-CD2 4.07Å; I97-F102 HydrophobicContact CG2-CE2 3.71Å; I97-V249 HydrophobicContact CD1-CG1 4.44Å; I97-L253 HydrophobicContact CB-CD2 3.8Å; I97-L253 HydrophobicContact CD1-CD1 4.41Å; I97-L253 HydrophobicContact CD1-CD2 4.44Å; I97-L253 HydrophobicContact CG2-CD2 3.61Å
98	P	94.6	Very high	92.7	Very high	0 Å²	0	34 Å²	34	0%	0	17%	0.167	C	C	.	.	I	π-helix	trans	-56.5	-43.2	173.7	-30.7	39.7	0	0	0	113.6	G94 L95 H100 F102 I103 L253	G94-P98 WeakPolarHBondContact O-CD 3.24Å; G94-P98 WeakPolarHBondContact O-CG 3.27Å; L95-P98 WeakPolarHBondContact O-CD 3.39Å; P98-H100 VanDerWaalsContact C-N 3.26Å; P98-H100 PolarHBondContact O-N 2.96Å; P98-F102 HydrophobicContact CB-CB 4.46Å; P98-F102 PolarHBondContact O-N 3.29Å; P98-I103 WeakPolarHBondContact O-CB 3.21Å; P98-I103 WeakPolarHBondContact O-CG1 3.42Å; P98-I103 PolarHBondContact O-N 3.11Å; P98-L253 HydrophobicContact CG-CD2 3.77Å
99	A	94.3	Very high	92.5	Very high	0 Å²	0	35.6 Å²	35.6	0%	0	17%	0.174	C	C	.	.	I	π-helix	trans	-57.7	-34.9	179.3	0	0	0	0	0	113.7	L95 L96 I97 P104 V276 C279 Y280	L95-A99 VanDerWaalsContact O-CB 3.23Å; L95-A99 WeakPolarHBondContact O-CB 3.31Å; L95-A99 PolarHBondContact O-N 3.15Å; L96-A99 PolarHBondContact O-N 2.89Å; I97-A99 VanDerWaalsContact C-N 3.32Å; I97-A99 PolarHBondContact O-N 2.81Å; A99-P104 WeakPolarHBondContact O-CD 3.48Å; A99-P104 WeakPolarHBondContact O-CG 3.31Å; A99-V276 HydrophobicContact CB-CG1 4.27Å; A99-V276 WeakPolarHBondContact O-CG2 3.25Å; A99-C279 HydrophobicContact CB-CB 4.38Å; A99-Y280 HydrophobicContact CB-CE1 4.42Å; A99-Y280 HydrophobicContact CB-CE2 4.03Å
100	H	91.7	Very high	92.2	Very high	99 Å²	99	40.2 Å²	40.2	46%	0.458	19%	0.188	S	C	.	.	I	π-helix	trans	-107.3	-12.9	-174.5	-76.5	-54.4	0	0	0	115.9	L96 I97 P98 Y280 Y541	L96-H100 PolarHBondContact O-N 3.28Å; I97-H100 PolarHBondContact O-N 3.01Å; P98-H100 VanDerWaalsContact C-N 3.26Å; P98-H100 PolarHBondContact O-N 2.96Å; H100-Y280 PolarHBondContact CD2-OH 3.13Å; H100-Y280 PolarHBondContact CE1-OH 3.33Å; H100-Y280 AromaticContact NE2-CZ 3.96Å; H100-Y280 PolarHBondContact NE2-OH 3.45Å; H100-Y541 WeakPolarHBondContact O-CE2 3.21Å; H100-Y541 PolarHBondContact O-OH 3.39Å
101	V	91.9	Very high	91.8	Very high	12 Å²	12	41.2 Å²	41.2	7%	0.073	19%	0.193	C	C	.	.	I	π-helix	trans	-121	-64.3	-175.1	-176.9	0	0	0	0	110.9	I97 L105 F433 Y541	I97-V101 HydrophobicContact CG2-CB 4.49Å; I97-V101 HydrophobicContact CG2-CG2 4.35Å; I97-V101 VanDerWaalsContact O-CB 3.29Å; I97-V101 WeakPolarHBondContact O-CB 3.25Å; I97-V101 PolarHBondContact O-N 3.41Å; V101-L105 WeakPolarHBondContact O-CB 3.4Å; V101-L105 PolarHBondContact O-N 2.82Å; V101-F433 HydrophobicContact CG1-CE1 3.59Å; V101-F433 HydrophobicContact CG1-CZ 3.71Å; V101-Y541 HydrophobicContact CB-CE2 4.34Å; V101-Y541 HydrophobicContact CG1-CD1 4.12Å; V101-Y541 HydrophobicContact CG1-CD2 3.93Å; V101-Y541 HydrophobicContact CG1-CE1 4.4Å; V101-Y541 HydrophobicContact CG1-CE2 4.19Å; V101-Y541 HydrophobicContact CG1-CG 3.89Å; V101-Y541 HydrophobicContact CG2-CE1 4.14Å; V101-Y541 HydrophobicContact CG2-CE2 4.37Å
102	F	94.1	Very high	91.4	Very high	1 Å²	1	41.2 Å²	41.2	0%	0.004	20%	0.197	C	C	.	.	I	π-helix	trans	-73.1	-50.3	-170.7	-67.2	-102.4	0	0	0	111.9	I97 P98 L105 L106 L253 V258 L425 F428 M432 F433	I97-F102 HydrophobicContact CG2-CD2 4.07Å; I97-F102 HydrophobicContact CG2-CE2 3.71Å; P98-F102 HydrophobicContact CB-CB 4.46Å; P98-F102 PolarHBondContact O-N 3.29Å; F102-L105 PolarHBondContact O-N 3.4Å; F102-L106 WeakPolarHBondContact O-CB 3.19Å; F102-L106 VanDerWaalsContact O-CG 3.32Å; F102-L106 WeakPolarHBondContact O-CG 3.38Å; F102-L106 PolarHBondContact O-N 2.87Å; F102-L253 HydrophobicContact CE2-CD2 4.22Å; F102-V258 HydrophobicContact CD1-CG1 3.74Å; F102-V258 HydrophobicContact CE1-CG1 3.54Å; F102-L425 HydrophobicContact CE1-CD1 4.27Å; F102-L425 HydrophobicContact CZ-CD1 4.13Å; F102-F428 HydrophobicContact CE1-CB 4.47Å; F102-M432 HydrophobicContact CD1-CE 3.61Å; F102-M432 HydrophobicContact CD1-SD 3.76Å; F102-M432 HydrophobicContact CE1-CE 4.07Å; F102-M432 HydrophobicContact CE1-SD 3.88Å; F102-M432 HydrophobicContact CG-CE 4.4Å; F102-M432 HydrophobicContact CG-SD 4.29Å; F102-F433 HydrophobicContact CE2-CZ 4.42Å; F102-F433 HydrophobicContact CZ-CZ 4.46Å
103	I	94.1	Very high	91.4	Very high	5 Å²	5	37 Å²	37	3%	0.026	18%	0.176	C	C	.	.	H	α-helix	trans	-62	-52.6	-176.2	-64.1	174.6	0	0	0	111.4	P98 L105 L106 Y107 Y266 A275 V276 C279	P98-I103 WeakPolarHBondContact O-CB 3.21Å; P98-I103 WeakPolarHBondContact O-CG1 3.42Å; P98-I103 PolarHBondContact O-N 3.11Å; I103-L105 VanDerWaalsContact C-N 3.28Å; I103-L105 PolarHBondContact O-N 3.09Å; I103-L106 PolarHBondContact O-N 3.33Å; I103-Y107 WeakPolarHBondContact O-CB 3.26Å; I103-Y107 PolarHBondContact O-N 3.06Å; I103-Y266 HydrophobicContact CD1-CD1 3.7Å; I103-Y266 HydrophobicContact CD1-CD2 3.73Å; I103-Y266 HydrophobicContact CD1-CE1 3.58Å; I103-Y266 HydrophobicContact CD1-CE2 3.68Å; I103-Y266 HydrophobicContact CD1-CG 3.78Å; I103-Y266 HydrophobicContact CG1-CD1 4.37Å; I103-Y266 HydrophobicContact CG1-CD2 3.63Å; I103-Y266 HydrophobicContact CG1-CE2 3.88Å; I103-Y266 HydrophobicContact CG1-CG 3.94Å; I103-Y266 HydrophobicContact CG2-CG 4.48Å; I103-A275 HydrophobicContact CG2-CB 3.85Å; I103-V276 HydrophobicContact CG2-CG2 4.05Å; I103-C279 HydrophobicContact CD1-CB 3.59Å
104	P	92.3	Very high	91.5	Very high	16 Å²	16	33 Å²	33	10%	0.104	15%	0.154	C	C	.	.	H	α-helix	trans	-59.6	-38.8	-179.3	-26.3	37.4	0	0	0	113	A99 R108 V276	A99-P104 WeakPolarHBondContact O-CD 3.48Å; A99-P104 WeakPolarHBondContact O-CG 3.31Å; P104-R108 WeakPolarHBondContact O-CD 3.4Å; P104-R108 WeakPolarHBondContact O-CG 3.27Å; P104-R108 PolarHBondContact O-N 3.26Å; P104-V276 HydrophobicContact CG-CG2 4.28Å
105	L	91.8	Very high	91.7	Very high	14 Å²	14	33 Å²	33	7%	0.073	16%	0.155	C	C	.	.	H	α-helix	trans	-66.3	-53.2	179.4	-175.1	149.3	0	0	0	110.8	V101 F102 I103 Y107 R108 L109 Y117 M432	V101-L105 WeakPolarHBondContact O-CB 3.4Å; V101-L105 PolarHBondContact O-N 2.82Å; F102-L105 PolarHBondContact O-N 3.4Å; I103-L105 VanDerWaalsContact C-N 3.28Å; I103-L105 PolarHBondContact O-N 3.09Å; L105-Y107 PolarHBondContact O-N 3.49Å; L105-R108 PolarHBondContact O-N 2.86Å; L105-L109 HydrophobicContact CD2-CD1 3.94Å; L105-L109 WeakPolarHBondContact O-CG 3.41Å; L105-L109 PolarHBondContact O-N 3.43Å; L105-Y117 HydrophobicContact CD2-CD2 3.83Å; L105-Y117 HydrophobicContact CD2-CE2 3.63Å; L105-M432 HydrophobicContact CD1-CG 4.2Å; L105-M432 HydrophobicContact CD1-SD 4.3Å; L105-M432 HydrophobicContact CD2-CE 3.99Å; L105-M432 HydrophobicContact CD2-SD 4.47Å
106	L	92.9	Very high	91.8	Very high	5 Å²	5	34.3 Å²	34.3	3%	0.026	16%	0.161	C	C	.	.	H	α-helix	trans	-67.2	-36.8	-177.8	-65.3	171.7	0	0	0	112	F102 I103 R108 L109 Y117 V263 F428 M432	F102-L106 WeakPolarHBondContact O-CB 3.19Å; F102-L106 VanDerWaalsContact O-CG 3.32Å; F102-L106 WeakPolarHBondContact O-CG 3.38Å; F102-L106 PolarHBondContact O-N 2.87Å; I103-L106 PolarHBondContact O-N 3.33Å; L106-R108 PolarHBondContact O-N 2.86Å; L106-L109 PolarHBondContact O-N 3.28Å; L106-Y117 HydrophobicContact CD2-CD2 4.45Å; L106-Y117 HydrophobicContact CD2-CG 4.11Å; L106-V263 HydrophobicContact CD1-CG1 3.91Å; L106-V263 HydrophobicContact CD1-CG2 3.95Å; L106-F428 HydrophobicContact CD2-CE1 4.45Å; L106-M432 HydrophobicContact CD1-CE 4.46Å; L106-M432 HydrophobicContact CD2-CE 4.3Å; L106-M432 HydrophobicContact CG-CE 4.3Å
107	Y	91.5	Very high	91.9	Very high	32 Å²	32	31 Å²	31	13%	0.125	14%	0.143	C	C	.	.	H	α-helix	trans	-63.1	-42	179.6	-166.1	-79.6	0	0	0	112.6	I103 L105 L109 K110 Y266 L267 A269 R270 T271 E272 A275	I103-Y107 WeakPolarHBondContact O-CB 3.26Å; I103-Y107 PolarHBondContact O-N 3.06Å; L105-Y107 PolarHBondContact O-N 3.49Å; Y107-L109 VanDerWaalsContact C-N 3.31Å; Y107-L109 PolarHBondContact O-N 2.86Å; Y107-K110 PolarHBondContact O-N 2.82Å; Y107-Y266 WeakPolarHBondContact CE2-O 3.36Å; Y107-L267 VanDerWaalsContact CA-CD2 3.42Å; Y107-L267 HydrophobicContact CD2-CD2 4.12Å; Y107-L267 HydrophobicContact CG-CD2 4.4Å; Y107-A269 HydrophobicContact CE2-CB 4.39Å; Y107-A269 PolarHBondContact OH-O 3.3Å; Y107-R270 PolarHBondContact OH-O 2.7Å; Y107-T271 VanDerWaalsContact CZ-C 3.42Å; Y107-T271 WeakPolarHBondContact OH-CA 3.41Å; Y107-T271 PolarHBondContact OH-N 3.17Å; Y107-T271 VanDerWaalsContact OH-N 3.14Å; Y107-E272 HydrophobicContact CD1-CB 3.7Å; Y107-E272 HydrophobicContact CD1-CG 4.22Å; Y107-E272 HydrophobicContact CE1-CB 3.91Å; Y107-E272 HydrophobicContact CG-CB 4.24Å; Y107-E272 HydrophobicContact CG-CG 4.42Å; Y107-A275 HydrophobicContact CD2-CB 3.83Å; Y107-A275 HydrophobicContact CE2-CB 3.97Å
108	R	90.4	Very high	91.9	Very high	145 Å²	145	28.4 Å²	28.4	55%	0.547	13%	0.13	S	C	.	.	H	α-helix	trans	-69.8	-27.9	-179.2	-70.8	172.9	-171.8	-174.2	7.6	113.4	P104 L105 L106 K110 E272	P104-R108 WeakPolarHBondContact O-CD 3.4Å; P104-R108 WeakPolarHBondContact O-CG 3.27Å; P104-R108 PolarHBondContact O-N 3.26Å; L105-R108 PolarHBondContact O-N 2.86Å; L106-R108 PolarHBondContact O-N 2.86Å; R108-K110 PolarHBondContact O-N 3.48Å; R108-E272 WeakPolarHBondContact CG-OE2 3.37Å; R108-E272 IonicContact CZ-OE1 3.58Å; R108-E272 IonicContact CZ-OE2 3.37Å; R108-E272 IonicContact NE-OE1 2.82Å; R108-E272 PolarHBondContact NE-OE1 3.44Å; R108-E272 IonicContact NE-OE2 3.51Å; R108-E272 PolarHBondContact NE-OE2 3.13Å; R108-E272 IonicContact NH2-OE1 3.45Å; R108-E272 PolarHBondContact NH2-OE1 3.33Å; R108-E272 IonicContact NH2-OE2 3.49Å; R108-E272 PolarHBondContact NH2-OE2 3.37Å
109	L	88.5	Confident	92	Very high	36 Å²	36	31.4 Å²	31.4	19%	0.188	14%	0.144	C	C	.	.	T	Hydrogen-bonded Turn	trans	-73.2	-13	176	-63.6	172.8	0	0	0	112.9	L105 L106 Y107 L111 Y117 L120	L105-L109 HydrophobicContact CD2-CD1 3.94Å; L105-L109 WeakPolarHBondContact O-CG 3.41Å; L105-L109 PolarHBondContact O-N 3.43Å; L106-L109 PolarHBondContact O-N 3.28Å; Y107-L109 VanDerWaalsContact C-N 3.31Å; Y107-L109 PolarHBondContact O-N 2.86Å; L109-L111 HydrophobicContact CB-CD1 3.85Å; L109-L111 HydrophobicContact CB-CD2 4.37Å; L109-L111 HydrophobicContact CB-CG 3.7Å; L109-L111 HydrophobicContact CD1-CD1 4.03Å; L109-L111 PolarHBondContact O-N 2.73Å; L109-L111 VanDerWaalsContact O-N 3.17Å; L109-Y117 HydrophobicContact CD1-CD2 3.66Å; L109-Y117 HydrophobicContact CD1-CE2 4.45Å; L109-L120 HydrophobicContact CD2-CD1 4.47Å
110	K	86	Confident	91.9	Very high	152 Å²	152	34.7 Å²	34.7	66%	0.661	16%	0.161	S	C	*	.	T	Hydrogen-bonded Turn	trans	53.5	34.9	176.8	-66.1	-176	177.8	179.8	0	113.6	R49 Y107 R108	R49-K110 VanDerWaalsContact NH1-CB 3.29Å; R49-K110 VanDerWaalsContact NH2-C 3.3Å; R49-K110 PolarHBondContact NH2-O 3.05Å; Y107-K110 PolarHBondContact O-N 2.82Å; R108-K110 PolarHBondContact O-N 3.48Å
111	L	85.4	Confident	92	Very high	20 Å²	20	30.1 Å²	30.1	11%	0.105	14%	0.14	C	C	.	.			trans	-76.2	160.2	-178.9	-58.4	174.5	0	0	0	112	R49 L109 Q116 L120 L267	R49-L111 PolarHBondContact NH2-O 2.69Å; L109-L111 HydrophobicContact CB-CD1 3.85Å; L109-L111 HydrophobicContact CB-CD2 4.37Å; L109-L111 HydrophobicContact CB-CG 3.7Å; L109-L111 HydrophobicContact CD1-CD1 4.03Å; L109-L111 PolarHBondContact O-N 2.73Å; L109-L111 VanDerWaalsContact O-N 3.17Å; L111-Q116 HydrophobicContact CB-CB 4.3Å; L111-Q116 HydrophobicContact CD1-CB 3.9Å; L111-Q116 HydrophobicContact CD2-CB 3.74Å; L111-Q116 HydrophobicContact CG-CB 4.17Å; L111-L120 HydrophobicContact CD1-CD1 4.42Å; L111-L120 HydrophobicContact CD2-CD1 4.03Å; L111-L267 WeakPolarHBondContact O-CD1 3.29Å
112	S	83.8	Confident	92.1	Very high	25 Å²	25	30.5 Å²	30.5	18%	0.175	14%	0.14	C	C	.	.	S	Bend	trans	-98.9	-35.6	170.5	-66.4	0	0	0	0	111.2	M46 Q260 T361	M46-S112 WeakPolarHBondContact CE-O 3.08Å; S112-Q260 PolarHBondContact O-NE2 3.16Å; S112-T361 WeakPolarHBondContact O-CG2 3.47Å
113	S	93	Very high	92.1	Very high	0 Å²	0	32 Å²	32	0%	0	15%	0.152	C	C	.	.	S	Bend	trans	-108.4	133.5	171.7	171.5	0	0	0	0	109.6	Y115 Q116 D366	S113-Y115 PolarHBondContact O-N 3.01Å; S113-Y115 WeakPolarHBondContact OG-CD2 3.28Å; S113-Y115 PolarHBondContact OG-N 3.01Å; S113-Y115 VanDerWaalsContact OG-N 3.12Å; S113-Q116 WeakPolarHBondContact O-CB 3.4Å; S113-Q116 PolarHBondContact O-N 3.36Å; S113-Q116 VanDerWaalsContact O-N 3.14Å; S113-D366 WeakPolarHBondContact CB-OD1 3.39Å; S113-D366 VanDerWaalsContact OG-CG 3.28Å; S113-D366 PolarHBondContact OG-OD1 2.98Å; S113-D366 VanDerWaalsContact OG-OD1 3.07Å; S113-D366 PolarHBondContact OG-OD2 2.95Å
114	A	93.4	Very high	92.1	Very high	1 Å²	1	35.9 Å²	35.9	1%	0.008	17%	0.168	C	C	.	.	T	Hydrogen-bonded Turn	trans	-57.2	-29.2	171.1	0	0	0	0	0	111.1	Q116 Y117 Q260 V263 F428	A114-Q116 VanDerWaalsContact C-N 3.31Å; A114-Q116 PolarHBondContact O-N 2.92Å; A114-Y117 WeakPolarHBondContact O-CB 3.11Å; A114-Y117 PolarHBondContact O-N 3.02Å; A114-Q260 VanDerWaalsContact CB-OE1 3.29Å; A114-V263 HydrophobicContact CB-CB 4.22Å; A114-V263 HydrophobicContact CB-CG1 3.86Å; A114-V263 HydrophobicContact CB-CG2 4.33Å; A114-F428 HydrophobicContact CB-CE1 4.46Å; A114-F428 HydrophobicContact CB-CZ 4.05Å; A114-F428 WeakPolarHBondContact O-CE1 3.37Å; A114-F428 WeakPolarHBondContact O-CZ 3.05Å
115	Y	95.4	Very high	92.4	Very high	1 Å²	1	39.1 Å²	39.1	0%	0.004	19%	0.187	C	C	.	.	T	Hydrogen-bonded Turn	trans	-76.6	-16.1	-178.2	-55.4	-74.9	0	0	0	113.4	S113 Y117 L118 E119 R127 T131 F134 Q260 V362 I424 F428	S113-Y115 PolarHBondContact O-N 3.01Å; S113-Y115 WeakPolarHBondContact OG-CD2 3.28Å; S113-Y115 PolarHBondContact OG-N 3.01Å; S113-Y115 VanDerWaalsContact OG-N 3.12Å; Y115-Y117 PolarHBondContact O-N 3.38Å; Y115-L118 HydrophobicContact CD1-CD1 3.86Å; Y115-L118 WeakPolarHBondContact O-CB 3.27Å; Y115-L118 PolarHBondContact O-N 2.89Å; Y115-E119 PolarHBondContact O-N 2.94Å; Y115-R127 WeakPolarHBondContact O-CG 3.47Å; Y115-T131 WeakPolarHBondContact CB-OG1 3.48Å; Y115-F134 HydrophobicContact CE1-CB 4.21Å; Y115-F134 HydrophobicContact CE2-CB 3.81Å; Y115-F134 AromaticContact CE2-CD1 3.93Å; Y115-F134 HydrophobicContact CE2-CD1 3.93Å; Y115-F134 HydrophobicContact CE2-CD2 4.37Å; Y115-F134 AromaticContact CE2-CG 3.76Å; Y115-F134 HydrophobicContact CE2-CG 3.76Å; Y115-F134 VanDerWaalsContact CZ-CB 3.44Å; Y115-F134 AromaticContact CZ-CG 3.68Å; Y115-F134 WeakPolarHBondContact OH-CB 3.36Å; Y115-F134 WeakPolarHBondContact OH-CD2 3.38Å; Y115-F134 WeakPolarHBondContact OH-CG 3.46Å; Y115-Q260 HydrophobicContact CE2-CB 4.34Å; Y115-V362 HydrophobicContact CD2-CG1 3.89Å; Y115-V362 HydrophobicContact CE2-CG1 3.94Å; Y115-I424 HydrophobicContact CE1-CG2 4.13Å; Y115-F428 HydrophobicContact CD1-CE2 4.05Å; Y115-F428 HydrophobicContact CD1-CZ 4.16Å; Y115-F428 AromaticContact CE1-CE2 3.83Å; Y115-F428 HydrophobicContact CE1-CE2 3.83Å; Y115-F428 HydrophobicContact CE1-CZ 4.24Å
116	Q	94.4	Very high	92.6	Very high	32 Å²	32	38.5 Å²	38.5	15%	0.15	18%	0.184	C	C	.	.	H	α-helix	trans	-58.9	-31	168.6	-75.7	167.9	-25.9	0	0	111.7	L111 S113 A114 L118 E119 L120 R127 E365	L111-Q116 HydrophobicContact CB-CB 4.3Å; L111-Q116 HydrophobicContact CD1-CB 3.9Å; L111-Q116 HydrophobicContact CD2-CB 3.74Å; L111-Q116 HydrophobicContact CG-CB 4.17Å; S113-Q116 WeakPolarHBondContact O-CB 3.4Å; S113-Q116 PolarHBondContact O-N 3.36Å; S113-Q116 VanDerWaalsContact O-N 3.14Å; A114-Q116 VanDerWaalsContact C-N 3.31Å; A114-Q116 PolarHBondContact O-N 2.92Å; Q116-L118 PolarHBondContact O-N 2.85Å; Q116-E119 PolarHBondContact O-N 3.27Å; Q116-L120 WeakPolarHBondContact O-CG 3.44Å; Q116-L120 PolarHBondContact O-N 3.3Å; Q116-R127 VanDerWaalsContact NE2-NH2 3.19Å; Q116-E365 PolarHBondContact NE2-OE2 2.6Å
117	Y	95.4	Very high	92.8	Very high	0 Å²	0	39.1 Å²	39.1	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-56.7	-40.6	172.9	164.8	-102.1	0	0	0	111.5	L105 L106 L109 A114 Y115 E119 L120 R121 F428 G431 M432 T539	L105-Y117 HydrophobicContact CD2-CD2 3.83Å; L105-Y117 HydrophobicContact CD2-CE2 3.63Å; L106-Y117 HydrophobicContact CD2-CD2 4.45Å; L106-Y117 HydrophobicContact CD2-CG 4.11Å; L109-Y117 HydrophobicContact CD1-CD2 3.66Å; L109-Y117 HydrophobicContact CD1-CE2 4.45Å; A114-Y117 WeakPolarHBondContact O-CB 3.11Å; A114-Y117 PolarHBondContact O-N 3.02Å; Y115-Y117 PolarHBondContact O-N 3.38Å; Y117-E119 VanDerWaalsContact C-N 3.31Å; Y117-E119 PolarHBondContact O-N 3Å; Y117-L120 PolarHBondContact O-N 3.45Å; Y117-R121 HydrophobicContact CE1-CB 4.49Å; Y117-R121 HydrophobicContact CE2-CB 4.37Å; Y117-R121 VanDerWaalsContact O-CB 3.29Å; Y117-R121 WeakPolarHBondContact O-CB 3.34Å; Y117-R121 PolarHBondContact O-N 2.83Å; Y117-F428 AromaticContact CD1-CD1 3.5Å; Y117-F428 HydrophobicContact CD1-CD1 3.5Å; Y117-F428 VanDerWaalsContact CD1-CD1 3.5Å; Y117-F428 AromaticContact CD1-CE1 3.5Å; Y117-F428 HydrophobicContact CD1-CE1 3.5Å; Y117-F428 AromaticContact CE1-CD1 3.8Å; Y117-F428 HydrophobicContact CE1-CD1 3.8Å; Y117-F428 HydrophobicContact CE1-CE1 4.28Å; Y117-F428 HydrophobicContact CG-CE1 4.25Å; Y117-G431 PolarHBondContact OH-O 3.47Å; Y117-M432 HydrophobicContact CE1-CE 4.26Å; Y117-M432 HydrophobicContact CE1-CG 4.04Å; Y117-M432 HydrophobicContact CE2-CG 4.48Å; Y117-M432 VanDerWaalsContact OH-CA 3.27Å; Y117-M432 WeakPolarHBondContact OH-CA 3.39Å; Y117-M432 WeakPolarHBondContact OH-CG 3.36Å; Y117-M432 PolarHBondContact OH-N 2.99Å; Y117-T539 HydrophobicContact CD2-CG2 4.48Å; Y117-T539 HydrophobicContact CE2-CG2 4.27Å; Y117-T539 VanDerWaalsContact CE2-O 3.24Å; Y117-T539 WeakPolarHBondContact CE2-O 3Å; Y117-T539 PolarHBondContact OH-O 3.09Å
118	L	95.9	Very high	93	Very high	0 Å²	0	40.1 Å²	40.1	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-69.1	-30.3	-179.1	-60.3	177.5	0	0	0	112.4	Y115 Q116 F122 S123 V126 L427 F428	Y115-L118 HydrophobicContact CD1-CD1 3.86Å; Y115-L118 WeakPolarHBondContact O-CB 3.27Å; Y115-L118 PolarHBondContact O-N 2.89Å; Q116-L118 PolarHBondContact O-N 2.85Å; L118-F122 WeakPolarHBondContact O-CA 3.48Å; L118-F122 WeakPolarHBondContact O-CB 3.3Å; L118-F122 PolarHBondContact O-N 3.24Å; L118-S123 PolarHBondContact O-N 2.67Å; L118-V126 HydrophobicContact CB-CG1 4.04Å; L118-V126 HydrophobicContact CD1-CG1 4.37Å; L118-L427 HydrophobicContact CD1-CD2 3.58Å; L118-L427 HydrophobicContact CD1-CG 4.15Å; L118-L427 HydrophobicContact CD2-CD2 4.37Å; L118-L427 HydrophobicContact CD2-CG 4.01Å; L118-F428 HydrophobicContact CD1-CE2 4.13Å; L118-F428 HydrophobicContact CD1-CZ 4.37Å; L118-F428 HydrophobicContact CD2-CD1 4.38Å; L118-F428 HydrophobicContact CD2-CD2 4.38Å; L118-F428 HydrophobicContact CD2-CE1 4.45Å; L118-F428 HydrophobicContact CD2-CE2 4.42Å; L118-F428 HydrophobicContact CD2-CG 4.37Å; L118-F428 HydrophobicContact CD2-CZ 4.46Å; L118-F428 HydrophobicContact CG-CE2 4.36Å; L118-F428 HydrophobicContact CG-CZ 4.22Å
119	E	94.8	Very high	93.4	Very high	64 Å²	64	35 Å²	35	30%	0.299	18%	0.179	S	C	.	.	H	α-helix	trans	-70.2	-46.4	171.8	176.6	167.8	-158.1	0	0	111.3	Y115 Q116 Y117 R121 F122 S123 K124 R127	Y115-E119 PolarHBondContact O-N 2.94Å; Q116-E119 PolarHBondContact O-N 3.27Å; Y117-E119 VanDerWaalsContact C-N 3.31Å; Y117-E119 PolarHBondContact O-N 3Å; E119-R121 PolarHBondContact O-N 3.46Å; E119-F122 CarbonylContact O-C 3.24Å; E119-F122 PolarHBondContact O-N 3.46Å; E119-S123 PolarHBondContact O-N 3.12Å; E119-K124 HydrophobicContact CG-CB 4.48Å; E119-R127 HydrophobicContact CB-CB 3.8Å; E119-R127 HydrophobicContact CB-CG 4.38Å; E119-R127 WeakPolarHBondContact OE2-CD 3.4Å; E119-R127 IonicContact OE2-CZ 3.71Å; E119-R127 IonicContact OE2-NE 3.64Å; E119-R127 IonicContact OE2-NH1 2.66Å; E119-R127 PolarHBondContact OE2-NH1 3.42Å
120	L	92.3	Very high	93.8	Very high	68 Å²	68	33.3 Å²	33.3	36%	0.356	17%	0.17	S	C	.	.	H	α-helix	trans	-60.5	-35.7	176.3	-67.5	176.7	0	0	0	112.1	L109 L111 Q116 Y117 T536 T539	L109-L120 HydrophobicContact CD2-CD1 4.47Å; L111-L120 HydrophobicContact CD1-CD1 4.42Å; L111-L120 HydrophobicContact CD2-CD1 4.03Å; Q116-L120 WeakPolarHBondContact O-CG 3.44Å; Q116-L120 PolarHBondContact O-N 3.3Å; Y117-L120 PolarHBondContact O-N 3.45Å; L120-T536 VanDerWaalsContact O-CB 3.28Å; L120-T536 WeakPolarHBondContact O-CB 3.49Å; L120-T536 PolarHBondContact O-OG1 3.31Å; L120-T539 HydrophobicContact CB-CG2 4.05Å
121	R	93.6	Very high	94.3	Very high	4 Å²	4	26 Å²	26	2%	0.015	14%	0.139	C	C	.	.	H	α-helix	trans	-83	-36.2	-178.9	178.4	59.2	-171	86.5	-2.2	112.9	Y117 E119 G431 F434 P435 A437 M530	Y117-R121 HydrophobicContact CE1-CB 4.49Å; Y117-R121 HydrophobicContact CE2-CB 4.37Å; Y117-R121 VanDerWaalsContact O-CB 3.29Å; Y117-R121 WeakPolarHBondContact O-CB 3.34Å; Y117-R121 PolarHBondContact O-N 2.83Å; E119-R121 PolarHBondContact O-N 3.46Å; R121-G431 PolarHBondContact NE-O 3.36Å; R121-F434 PolarHBondContact NH2-O 3.44Å; R121-P435 PolarHBondContact NH2-O 3.02Å; R121-A437 PolarHBondContact NH1-O 2.79Å; R121-A437 PolarHBondContact NH2-O 3.5Å; R121-M530 PolarHBondContact NH1-SD 3.1Å
122	F	94.6	Very high	94.9	Very high	19 Å²	19	29.5 Å²	29.5	8%	0.083	16%	0.157	C	C	.	.	T	Hydrogen-bonded Turn	trans	-128.4	-81	-171.6	-62.1	-68	0	0	0	111.8	L118 E119 V126 L430 G431 A437 S439 A442	L118-F122 WeakPolarHBondContact O-CA 3.48Å; L118-F122 WeakPolarHBondContact O-CB 3.3Å; L118-F122 PolarHBondContact O-N 3.24Å; E119-F122 CarbonylContact O-C 3.24Å; E119-F122 PolarHBondContact O-N 3.46Å; F122-V126 HydrophobicContact CB-CB 4.04Å; F122-V126 HydrophobicContact CB-CG1 4.33Å; F122-V126 HydrophobicContact CB-CG2 3.74Å; F122-V126 HydrophobicContact CD2-CG1 3.97Å; F122-V126 HydrophobicContact CG-CG1 4.48Å; F122-V126 HydrophobicContact CG-CG2 4.4Å; F122-L430 HydrophobicContact CZ-CG 4.39Å; F122-G431 VanDerWaalsContact CZ-CA 3.44Å; F122-A437 HydrophobicContact CE1-CB 3.98Å; F122-A437 WeakPolarHBondContact CE1-O 3.35Å; F122-A437 HydrophobicContact CZ-CB 4.27Å; F122-S439 WeakPolarHBondContact CA-OG 3.3Å; F122-S439 WeakPolarHBondContact CB-OG 3.46Å; F122-S439 PolarHBondContact O-OG 2.99Å; F122-A442 HydrophobicContact CD1-CB 4.04Å; F122-A442 HydrophobicContact CD2-CB 4.03Å; F122-A442 HydrophobicContact CE1-CB 4.05Å; F122-A442 HydrophobicContact CE2-CB 4.03Å; F122-A442 HydrophobicContact CG-CB 4.02Å; F122-A442 HydrophobicContact CZ-CB 4.02Å
123	S	94.9	Very high	95.5	Very high	34 Å²	34	29 Å²	29	24%	0.238	15%	0.153	C	C	.	.			trans	-169.8	164.9	-177.8	61.5	0	0	0	0	111.4	L118 E119 V125 V126 R127	L118-S123 PolarHBondContact O-N 2.67Å; E119-S123 PolarHBondContact O-N 3.12Å; S123-V125 PolarHBondContact O-N 2.88Å; S123-V126 PolarHBondContact O-N 3.44Å; S123-V126 VanDerWaalsContact O-N 3.09Å; S123-R127 PolarHBondContact O-N 3.31Å
124	K	94.8	Very high	95.7	Very high	85 Å²	85	29.1 Å²	29.1	37%	0.37	15%	0.153	S	C	.	.	H	α-helix	trans	-54.8	-34.7	175.4	-170.1	173.1	-178.8	-179.9	0	113.3	E119 R127 I128	E119-K124 HydrophobicContact CG-CB 4.48Å; K124-R127 PolarHBondContact O-N 2.9Å; K124-I128 HydrophobicContact CG-CD1 4.18Å; K124-I128 WeakPolarHBondContact O-CG1 3.19Å; K124-I128 PolarHBondContact O-N 3.33Å
125	V	96.6	Very high	95.9	Very high	84 Å²	84	30 Å²	30	51%	0.509	16%	0.158	S	C	.	.	H	α-helix	trans	-62.1	-45.9	177.5	179.5	0	0	0	0	110.7	S123 R127 I128 C129 V443	S123-V125 PolarHBondContact O-N 2.88Å; V125-R127 VanDerWaalsContact C-N 3.33Å; V125-R127 PolarHBondContact O-N 2.87Å; V125-I128 PolarHBondContact O-N 2.7Å; V125-C129 PolarHBondContact O-N 3.07Å; V125-C129 PolarHBondContact O-SG 3.43Å; V125-V443 HydrophobicContact CG1-CG2 4.03Å
126	V	97	Very high	95.8	Very high	1 Å²	1	34.6 Å²	34.6	1%	0.006	18%	0.178	C	C	.	.	H	α-helix	trans	-64.7	-39.2	-179.9	-176.2	0	0	0	0	111.1	L118 F122 S123 C129 G130 L427 A442 V443	L118-V126 HydrophobicContact CB-CG1 4.04Å; L118-V126 HydrophobicContact CD1-CG1 4.37Å; F122-V126 HydrophobicContact CB-CB 4.04Å; F122-V126 HydrophobicContact CB-CG1 4.33Å; F122-V126 HydrophobicContact CB-CG2 3.74Å; F122-V126 HydrophobicContact CD2-CG1 3.97Å; F122-V126 HydrophobicContact CG-CG1 4.48Å; F122-V126 HydrophobicContact CG-CG2 4.4Å; S123-V126 PolarHBondContact O-N 3.44Å; S123-V126 VanDerWaalsContact O-N 3.09Å; V126-C129 PolarHBondContact O-N 2.98Å; V126-G130 PolarHBondContact O-N 3.48Å; V126-L427 HydrophobicContact CG1-CD1 3.88Å; V126-L427 HydrophobicContact CG1-CD2 4Å; V126-L427 HydrophobicContact CG1-CG 4.29Å; V126-A442 HydrophobicContact CG1-CB 4.05Å; V126-A442 HydrophobicContact CG2-CB 3.89Å; V126-V443 HydrophobicContact CG2-CG2 3.75Å
127	R	96.4	Very high	95.8	Very high	19 Å²	19	33.2 Å²	33.2	7%	0.072	17%	0.171	C	C	.	.	H	α-helix	trans	-56.6	-53.5	172	171.1	177.9	-174.4	-166	-1.1	111.3	Y115 Q116 E119 S123 K124 V125 C129 G130 T131 E365 D366	Y115-R127 WeakPolarHBondContact O-CG 3.47Å; Q116-R127 VanDerWaalsContact NE2-NH2 3.19Å; E119-R127 HydrophobicContact CB-CB 3.8Å; E119-R127 HydrophobicContact CB-CG 4.38Å; E119-R127 WeakPolarHBondContact OE2-CD 3.4Å; E119-R127 IonicContact OE2-CZ 3.71Å; E119-R127 IonicContact OE2-NE 3.64Å; E119-R127 IonicContact OE2-NH1 2.66Å; E119-R127 PolarHBondContact OE2-NH1 3.42Å; S123-R127 PolarHBondContact O-N 3.31Å; K124-R127 PolarHBondContact O-N 2.9Å; V125-R127 VanDerWaalsContact C-N 3.33Å; V125-R127 PolarHBondContact O-N 2.87Å; R127-C129 PolarHBondContact O-N 3.36Å; R127-G130 PolarHBondContact O-N 3.03Å; R127-T131 PolarHBondContact O-N 3.35Å; R127-T131 PolarHBondContact O-OG1 3.43Å; R127-T131 VanDerWaalsContact O-OG1 3.05Å; R127-E365 VanDerWaalsContact NH2-C 3.26Å; R127-E365 PolarHBondContact NH2-O 3.38Å; R127-D366 HydrophobicContact CG-CB 4.48Å; R127-D366 IonicContact CZ-OD1 2.76Å; R127-D366 IonicContact NE-OD1 2.8Å; R127-D366 PolarHBondContact NE-OD1 3.15Å; R127-D366 IonicContact NH2-OD1 3.82Å; R127-D366 PolarHBondContact NH2-OD1 3.23Å
128	I	97.3	Very high	95.7	Very high	53 Å²	53	33.4 Å²	33.4	27%	0.272	17%	0.172	S	C	.	.	H	α-helix	trans	-60.7	-45.8	-178.6	-66	168.9	0	0	0	110.9	K124 V125 G130 T131 L132 L367	K124-I128 HydrophobicContact CG-CD1 4.18Å; K124-I128 WeakPolarHBondContact O-CG1 3.19Å; K124-I128 PolarHBondContact O-N 3.33Å; V125-I128 PolarHBondContact O-N 2.7Å; I128-G130 VanDerWaalsContact C-N 3.35Å; I128-G130 PolarHBondContact O-N 3.31Å; I128-T131 PolarHBondContact O-N 3.4Å; I128-L132 HydrophobicContact CG2-CD1 3.84Å; I128-L132 HydrophobicContact CG2-CG 4.18Å; I128-L132 WeakPolarHBondContact O-CB 3.39Å; I128-L132 VanDerWaalsContact O-CG 3.31Å; I128-L132 WeakPolarHBondContact O-CG 3.41Å; I128-L132 PolarHBondContact O-N 3.3Å; I128-L367 HydrophobicContact CG2-CD2 4.38Å
129	C	97.8	Very high	95.6	Very high	37 Å²	37	34 Å²	34	25%	0.25	18%	0.176	C	C	.	.	H	α-helix	trans	-60.4	-43.7	177.7	-65.6	0	0	0	0	112.1	V125 V126 R127 T133 L446	V125-C129 PolarHBondContact O-N 3.07Å; V125-C129 PolarHBondContact O-SG 3.43Å; V126-C129 PolarHBondContact O-N 2.98Å; R127-C129 PolarHBondContact O-N 3.36Å; C129-T133 WeakPolarHBondContact O-CB 3.47Å; C129-T133 PolarHBondContact O-N 2.83Å; C129-T133 PolarHBondContact O-OG1 2.88Å; C129-L446 HydrophobicContact CB-CD2 3.66Å
130	G	97.2	Very high	95.4	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-61.5	-47.2	175.4	0	0	0	0	0	112.4	V126 R127 I128 T133 F134	V126-G130 PolarHBondContact O-N 3.48Å; R127-G130 PolarHBondContact O-N 3.03Å; I128-G130 VanDerWaalsContact C-N 3.35Å; I128-G130 PolarHBondContact O-N 3.31Å; G130-T133 PolarHBondContact O-N 3.02Å; G130-F134 PolarHBondContact O-N 3.47Å
131	T	97.3	Very high	95.4	Very high	0 Å²	0	29.9 Å²	29.9	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-60.8	-47.2	177.9	-60.1	0	0	0	0	112.1	Y115 R127 I128 T133 F134 I135 V362 D366 L367	Y115-T131 WeakPolarHBondContact CB-OG1 3.48Å; R127-T131 PolarHBondContact O-N 3.35Å; R127-T131 PolarHBondContact O-OG1 3.43Å; R127-T131 VanDerWaalsContact O-OG1 3.05Å; I128-T131 PolarHBondContact O-N 3.4Å; T131-T133 VanDerWaalsContact C-N 3.33Å; T131-T133 PolarHBondContact O-N 3.24Å; T131-F134 WeakPolarHBondContact O-CB 3.41Å; T131-F134 PolarHBondContact O-N 3.05Å; T131-I135 HydrophobicContact CG2-CD1 3.81Å; T131-I135 HydrophobicContact CG2-CG1 4.38Å; T131-I135 WeakPolarHBondContact O-CG1 3.46Å; T131-I135 PolarHBondContact O-N 2.66Å; T131-V362 HydrophobicContact CG2-CB 3.92Å; T131-V362 HydrophobicContact CG2-CG2 4.07Å; T131-D366 HydrophobicContact CG2-CB 3.95Å; T131-D366 PolarHBondContact OG1-OD2 3.37Å; T131-L367 HydrophobicContact CG2-CG 4.48Å
132	L	97.3	Very high	95.2	Very high	92 Å²	92	29.7 Å²	29.7	48%	0.482	16%	0.155	S	C	.	.	H	α-helix	trans	-63.7	-39.4	179.4	-69.5	177	0	0	0	111.9	I128 F134 I135 F136 L367	I128-L132 HydrophobicContact CG2-CD1 3.84Å; I128-L132 HydrophobicContact CG2-CG 4.18Å; I128-L132 WeakPolarHBondContact O-CB 3.39Å; I128-L132 VanDerWaalsContact O-CG 3.31Å; I128-L132 WeakPolarHBondContact O-CG 3.41Å; I128-L132 PolarHBondContact O-N 3.3Å; L132-F134 VanDerWaalsContact C-N 3.32Å; L132-F134 PolarHBondContact O-N 3.42Å; L132-I135 PolarHBondContact O-N 3.45Å; L132-F136 WeakPolarHBondContact O-CB 3.18Å; L132-F136 PolarHBondContact O-N 2.97Å; L132-L367 HydrophobicContact CD2-CD1 4.3Å
133	T	97.3	Very high	95	Very high	16 Å²	16	28.8 Å²	28.8	10%	0.098	15%	0.151	C	C	.	.	H	α-helix	trans	-62.7	-41.5	176.4	-54.7	0	0	0	0	111.1	C129 G130 T131 Q137 V420 I424 L450	C129-T133 WeakPolarHBondContact O-CB 3.47Å; C129-T133 PolarHBondContact O-N 2.83Å; C129-T133 PolarHBondContact O-OG1 2.88Å; G130-T133 PolarHBondContact O-N 3.02Å; T131-T133 VanDerWaalsContact C-N 3.33Å; T131-T133 PolarHBondContact O-N 3.24Å; T133-Q137 PolarHBondContact O-N 3.44Å; T133-V420 HydrophobicContact CG2-CG1 3.51Å; T133-V420 WeakPolarHBondContact O-CG1 3.28Å; T133-I424 HydrophobicContact CG2-CD1 3.9Å; T133-I424 HydrophobicContact CG2-CG1 3.75Å; T133-L450 HydrophobicContact CG2-CD1 4.09Å; T133-L450 HydrophobicContact CG2-CD2 3.75Å; T133-L450 HydrophobicContact CG2-CG 4.45Å
134	F	96.9	Very high	94.8	Very high	1 Å²	1	27.2 Å²	27.2	0%	0.004	14%	0.14	C	C	.	.	H	α-helix	trans	-66.6	-44.8	175.4	170.1	-99.2	0	0	0	113.3	Y115 G130 T131 L132 F136 Q137 M138 Q260 L359 V362 I424	Y115-F134 HydrophobicContact CE1-CB 4.21Å; Y115-F134 HydrophobicContact CE2-CB 3.81Å; Y115-F134 AromaticContact CE2-CD1 3.93Å; Y115-F134 HydrophobicContact CE2-CD1 3.93Å; Y115-F134 HydrophobicContact CE2-CD2 4.37Å; Y115-F134 AromaticContact CE2-CG 3.76Å; Y115-F134 HydrophobicContact CE2-CG 3.76Å; Y115-F134 VanDerWaalsContact CZ-CB 3.44Å; Y115-F134 AromaticContact CZ-CG 3.68Å; Y115-F134 WeakPolarHBondContact OH-CB 3.36Å; Y115-F134 WeakPolarHBondContact OH-CD2 3.38Å; Y115-F134 WeakPolarHBondContact OH-CG 3.46Å; G130-F134 PolarHBondContact O-N 3.47Å; T131-F134 WeakPolarHBondContact O-CB 3.41Å; T131-F134 PolarHBondContact O-N 3.05Å; L132-F134 VanDerWaalsContact C-N 3.32Å; L132-F134 PolarHBondContact O-N 3.42Å; F134-F136 VanDerWaalsContact C-N 3.28Å; F134-F136 PolarHBondContact O-N 3.25Å; F134-Q137 WeakPolarHBondContact O-CB 3.4Å; F134-Q137 PolarHBondContact O-N 3.44Å; F134-M138 HydrophobicContact CD2-CG 3.85Å; F134-M138 HydrophobicContact CE1-CG 4.05Å; F134-M138 HydrophobicContact CE2-CE 4.46Å; F134-M138 HydrophobicContact CE2-CG 3.3Å; F134-M138 HydrophobicContact CE2-SD 3.97Å; F134-M138 HydrophobicContact CG-CG 4.43Å; F134-M138 HydrophobicContact CZ-CB 4.44Å; F134-M138 HydrophobicContact CZ-CE 4.36Å; F134-M138 HydrophobicContact CZ-CG 3.4Å; F134-M138 HydrophobicContact CZ-SD 4.33Å; F134-M138 WeakPolarHBondContact O-CG 3.29Å; F134-M138 PolarHBondContact O-N 3.4Å; F134-Q260 HydrophobicContact CD2-CB 4.49Å; F134-Q260 HydrophobicContact CE1-CB 3.84Å; F134-Q260 HydrophobicContact CE1-CG 4.43Å; F134-Q260 HydrophobicContact CE2-CB 3.8Å; F134-Q260 HydrophobicContact CZ-CB 3.44Å; F134-Q260 VanDerWaalsContact CZ-CB 3.44Å; F134-Q260 HydrophobicContact CZ-CG 4.32Å; F134-L359 HydrophobicContact CE1-CD2 4.25Å; F134-V362 HydrophobicContact CD1-CG1 4.27Å; F134-V362 HydrophobicContact CD1-CG2 3.91Å; F134-V362 HydrophobicContact CE1-CG1 4.15Å; F134-V362 HydrophobicContact CE1-CG2 3.93Å; F134-I424 HydrophobicContact CB-CD1 3.99Å
135	I	96.2	Very high	94.6	Very high	21 Å²	21	23.2 Å²	23.2	11%	0.108	12%	0.123	C	C	.	.	H	α-helix	trans	-57.2	-48.3	176.3	-71	167.7	0	0	0	109.3	T131 L132 Q137 M138 V139 L359 V362 L367 Y391	T131-I135 HydrophobicContact CG2-CD1 3.81Å; T131-I135 HydrophobicContact CG2-CG1 4.38Å; T131-I135 WeakPolarHBondContact O-CG1 3.46Å; T131-I135 PolarHBondContact O-N 2.66Å; L132-I135 PolarHBondContact O-N 3.45Å; I135-Q137 PolarHBondContact O-N 2.74Å; I135-M138 PolarHBondContact O-N 2.8Å; I135-V139 HydrophobicContact CG2-CG2 4.24Å; I135-V139 WeakPolarHBondContact O-CB 3.41Å; I135-V139 VanDerWaalsContact O-CG2 3.24Å; I135-V139 WeakPolarHBondContact O-CG2 3.46Å; I135-V139 PolarHBondContact O-N 3.43Å; I135-L359 HydrophobicContact CB-CD2 4.08Å; I135-L359 HydrophobicContact CG1-CD2 3.87Å; I135-L359 HydrophobicContact CG2-CD2 4.1Å; I135-V362 HydrophobicContact CD1-CG2 4.2Å; I135-V362 HydrophobicContact CG1-CG2 3.92Å; I135-L367 HydrophobicContact CD1-CD1 4.06Å; I135-Y391 HydrophobicContact CG2-CE1 3.97Å
136	F	94.6	Very high	94.3	Very high	97 Å²	97	19.3 Å²	19.3	43%	0.425	10%	0.099	S	C	.	.	H	α-helix	trans	-56.6	-49.5	176.6	176.6	-93	0	0	0	112.2	L132 F134 M138 I140 V420 F454	L132-F136 WeakPolarHBondContact O-CB 3.18Å; L132-F136 PolarHBondContact O-N 2.97Å; F134-F136 VanDerWaalsContact C-N 3.28Å; F134-F136 PolarHBondContact O-N 3.25Å; F136-M138 PolarHBondContact O-N 2.98Å; F136-I140 HydrophobicContact CD1-CD1 3.97Å; F136-I140 HydrophobicContact CD2-CD1 4.31Å; F136-I140 HydrophobicContact CE1-CD1 3.36Å; F136-I140 HydrophobicContact CE2-CD1 3.79Å; F136-I140 HydrophobicContact CG-CD1 4.41Å; F136-I140 HydrophobicContact CZ-CD1 3.3Å; F136-I140 WeakPolarHBondContact O-CG1 3.32Å; F136-I140 PolarHBondContact O-N 2.9Å; F136-V420 HydrophobicContact CD1-CG1 4.26Å; F136-V420 HydrophobicContact CD1-CG2 4.23Å; F136-V420 HydrophobicContact CE1-CG2 4.11Å; F136-F454 HydrophobicContact CD1-CZ 4.5Å; F136-F454 HydrophobicContact CE1-CE1 4.15Å; F136-F454 AromaticContact CE1-CZ 3.59Å; F136-F454 HydrophobicContact CE1-CZ 3.59Å; F136-F454 HydrophobicContact CZ-CE1 4.42Å; F136-F454 HydrophobicContact CZ-CZ 4.07Å
137	Q	94.8	Very high	93.9	Very high	3 Å²	3	20 Å²	20	1%	0.014	10%	0.101	C	C	.	.	H	α-helix	trans	-56.5	-51.7	177.6	-176.2	-178.8	-37.4	0	0	112.4	T133 F134 I135 I140 Y141 I416 V420	T133-Q137 PolarHBondContact O-N 3.44Å; F134-Q137 WeakPolarHBondContact O-CB 3.4Å; F134-Q137 PolarHBondContact O-N 3.44Å; I135-Q137 PolarHBondContact O-N 2.74Å; Q137-I140 PolarHBondContact O-N 3.07Å; Q137-Y141 PolarHBondContact O-N 3.32Å; Q137-I416 HydrophobicContact CG-CG2 4.07Å; Q137-V420 HydrophobicContact CB-CB 3.89Å; Q137-V420 HydrophobicContact CB-CG1 3.6Å; Q137-V420 HydrophobicContact CG-CB 3.91Å; Q137-V420 HydrophobicContact CG-CG1 4.16Å; Q137-V420 VanDerWaalsContact OE1-C 3.28Å
138	M	93.4	Very high	93.6	Very high	3 Å²	3	19.1 Å²	19.1	2%	0.015	10%	0.098	C	C	.	.	H	α-helix	trans	-70.9	-36.8	-172.4	-70.3	-61.9	-81.6	0	0	111.6	F134 I135 F136 I140 Y141 M142 A261 A355 L359	F134-M138 HydrophobicContact CD2-CG 3.85Å; F134-M138 HydrophobicContact CE1-CG 4.05Å; F134-M138 HydrophobicContact CE2-CE 4.46Å; F134-M138 HydrophobicContact CE2-CG 3.3Å; F134-M138 HydrophobicContact CE2-SD 3.97Å; F134-M138 HydrophobicContact CG-CG 4.43Å; F134-M138 HydrophobicContact CZ-CB 4.44Å; F134-M138 HydrophobicContact CZ-CE 4.36Å; F134-M138 HydrophobicContact CZ-CG 3.4Å; F134-M138 HydrophobicContact CZ-SD 4.33Å; F134-M138 WeakPolarHBondContact O-CG 3.29Å; F134-M138 PolarHBondContact O-N 3.4Å; I135-M138 PolarHBondContact O-N 2.8Å; F136-M138 PolarHBondContact O-N 2.98Å; M138-I140 VanDerWaalsContact C-N 3.33Å; M138-I140 PolarHBondContact O-N 3.24Å; M138-Y141 PolarHBondContact O-N 2.89Å; M138-M142 HydrophobicContact CE-CE 4.47Å; M138-M142 WeakPolarHBondContact O-CB 3.39Å; M138-M142 VanDerWaalsContact O-CG 3.23Å; M138-M142 WeakPolarHBondContact O-CG 3.23Å; M138-M142 PolarHBondContact O-N 2.99Å; M138-A261 HydrophobicContact CE-CB 4.35Å; M138-A355 HydrophobicContact CE-CB 3.58Å; M138-L359 HydrophobicContact CB-CD1 4.27Å; M138-L359 HydrophobicContact CB-CD2 4.01Å; M138-L359 HydrophobicContact CB-CG 4.23Å
139	V	92.4	Very high	93.2	Very high	13 Å²	13	16.6 Å²	16.6	8%	0.079	9%	0.085	C	C	.	.	H	α-helix	trans	-59.4	-43.7	175.1	165.3	0	0	0	0	111.4	I135 M142 G143 L359 Y391 L394 M398	I135-V139 HydrophobicContact CG2-CG2 4.24Å; I135-V139 WeakPolarHBondContact O-CB 3.41Å; I135-V139 VanDerWaalsContact O-CG2 3.24Å; I135-V139 WeakPolarHBondContact O-CG2 3.46Å; I135-V139 PolarHBondContact O-N 3.43Å; V139-M142 PolarHBondContact O-N 3.37Å; V139-G143 PolarHBondContact O-N 3.26Å; V139-L359 HydrophobicContact CG2-CD1 4.41Å; V139-Y391 HydrophobicContact CG2-CD1 3.97Å; V139-Y391 HydrophobicContact CG2-CE1 4.03Å; V139-L394 HydrophobicContact CB-CD2 4.48Å; V139-L394 HydrophobicContact CG1-CD2 3.7Å; V139-L394 HydrophobicContact CG1-CG 3.89Å; V139-L394 HydrophobicContact CG2-CD2 3.87Å; V139-M398 HydrophobicContact CG1-CG 3.67Å; V139-M398 HydrophobicContact CG1-SD 4.32Å
140	I	91	Very high	92.9	Very high	40 Å²	40	14.9 Å²	14.9	21%	0.205	7%	0.073	C	C	.	.	H	α-helix	trans	-66.4	-47.4	177.1	-60.5	172.1	0	0	0	110.8	F136 Q137 M138 M142 G143 M398 I416	F136-I140 HydrophobicContact CD1-CD1 3.97Å; F136-I140 HydrophobicContact CD2-CD1 4.31Å; F136-I140 HydrophobicContact CE1-CD1 3.36Å; F136-I140 HydrophobicContact CE2-CD1 3.79Å; F136-I140 HydrophobicContact CG-CD1 4.41Å; F136-I140 HydrophobicContact CZ-CD1 3.3Å; F136-I140 WeakPolarHBondContact O-CG1 3.32Å; F136-I140 PolarHBondContact O-N 2.9Å; Q137-I140 PolarHBondContact O-N 3.07Å; M138-I140 VanDerWaalsContact C-N 3.33Å; M138-I140 PolarHBondContact O-N 3.24Å; I140-M142 VanDerWaalsContact C-N 3.27Å; I140-M142 PolarHBondContact O-N 3.25Å; I140-G143 PolarHBondContact O-N 3.44Å; I140-M398 HydrophobicContact CB-CE 4.32Å; I140-M398 HydrophobicContact CG1-CE 3.88Å; I140-M398 HydrophobicContact CG2-CE 4.38Å; I140-I416 HydrophobicContact CG2-CD1 3.59Å; I140-I416 HydrophobicContact CG2-CG1 3.97Å
141	Y	92.2	Very high	92.4	Very high	6 Å²	6	16 Å²	16	2%	0.024	8%	0.078	C	C	.	.	H	α-helix	trans	-60.7	-36.9	179.5	177.5	-123	0	0	0	112.4	F64 S66 Q137 M138 G143 V144 C145 T351 A413 F417	F64-Y141 HydrophobicContact CE1-CE1 4.36Å; S66-Y141 PolarHBondContact OG-OH 2.77Å; Q137-Y141 PolarHBondContact O-N 3.32Å; M138-Y141 PolarHBondContact O-N 2.89Å; Y141-G143 VanDerWaalsContact C-N 3.32Å; Y141-G143 PolarHBondContact O-N 3.14Å; Y141-V144 WeakPolarHBondContact O-CB 3.27Å; Y141-V144 PolarHBondContact O-N 3.13Å; Y141-V144 VanDerWaalsContact O-N 3.07Å; Y141-C145 VanDerWaalsContact CE1-SG 3.51Å; Y141-C145 VanDerWaalsContact CE2-SG 3.51Å; Y141-C145 PolarHBondContact O-N 3.26Å; Y141-C145 PolarHBondContact O-SG 3.34Å; Y141-T351 HydrophobicContact CE1-CG2 3.71Å; Y141-A413 HydrophobicContact CD2-CB 4.18Å; Y141-A413 HydrophobicContact CE2-CB 3.89Å; Y141-F417 AromaticContact CD1-CE2 3.98Å; Y141-F417 HydrophobicContact CD1-CE2 3.98Å; Y141-F417 AromaticContact CD1-CZ 3.5Å; Y141-F417 HydrophobicContact CD1-CZ 3.5Å; Y141-F417 AromaticContact CD2-CE2 3.6Å; Y141-F417 HydrophobicContact CD2-CE2 3.6Å; Y141-F417 AromaticContact CD2-CZ 3.98Å; Y141-F417 HydrophobicContact CD2-CZ 3.98Å; Y141-F417 AromaticContact CE1-CE2 3.93Å; Y141-F417 HydrophobicContact CE1-CE2 3.93Å; Y141-F417 AromaticContact CE1-CZ 3.62Å; Y141-F417 HydrophobicContact CE1-CZ 3.62Å; Y141-F417 AromaticContact CE2-CE2 3.54Å; Y141-F417 HydrophobicContact CE2-CE2 3.54Å; Y141-F417 HydrophobicContact CE2-CZ 4.08Å; Y141-F417 AromaticContact CG-CE2 3.83Å; Y141-F417 HydrophobicContact CG-CE2 3.83Å; Y141-F417 AromaticContact CG-CZ 3.71Å; Y141-F417 HydrophobicContact CG-CZ 3.71Å; Y141-F417 AromaticContact CZ-CE2 3.71Å; Y141-F417 AromaticContact CZ-CZ 3.91Å
142	M	90.1	Very high	92	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-64	-34	177.7	-74.8	-49.3	97.6	0	0	113.6	M138 V139 I140 V144 C145 V146 T351 I352 A355 F356 C395	M138-M142 HydrophobicContact CE-CE 4.47Å; M138-M142 WeakPolarHBondContact O-CB 3.39Å; M138-M142 VanDerWaalsContact O-CG 3.23Å; M138-M142 WeakPolarHBondContact O-CG 3.23Å; M138-M142 PolarHBondContact O-N 2.99Å; V139-M142 PolarHBondContact O-N 3.37Å; I140-M142 VanDerWaalsContact C-N 3.27Å; I140-M142 PolarHBondContact O-N 3.25Å; M142-V144 VanDerWaalsContact C-N 3.25Å; M142-V144 PolarHBondContact O-N 2.84Å; M142-C145 HydrophobicContact CE-CB 4.4Å; M142-C145 PolarHBondContact O-N 3.33Å; M142-V146 VanDerWaalsContact O-CG2 3.31Å; M142-V146 WeakPolarHBondContact O-CG2 3.44Å; M142-V146 PolarHBondContact O-N 3.26Å; M142-T351 HydrophobicContact CE-CG2 4.03Å; M142-I352 HydrophobicContact SD-CB 4.21Å; M142-I352 HydrophobicContact SD-CG1 4.02Å; M142-I352 HydrophobicContact SD-CG2 4.36Å; M142-A355 HydrophobicContact CE-CB 3.48Å; M142-A355 VanDerWaalsContact CE-CB 3.48Å; M142-A355 HydrophobicContact CG-CB 3.7Å; M142-A355 HydrophobicContact SD-CB 3.19Å; M142-A355 WeakPolarHBondContact SD-CB 3.33Å; M142-F356 HydrophobicContact CG-CE1 4.2Å; M142-C395 HydrophobicContact CB-CB 4.12Å; M142-C395 WeakPolarHBondContact CB-SG 3.29Å
143	G	89.6	Confident	91.5	Very high	0 Å²	0	12.1 Å²	12.1	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-55.9	-43.8	170.9	0	0	0	0	0	111.9	V139 I140 Y141 Y147	V139-G143 PolarHBondContact O-N 3.26Å; I140-G143 PolarHBondContact O-N 3.44Å; Y141-G143 VanDerWaalsContact C-N 3.32Å; Y141-G143 PolarHBondContact O-N 3.14Å; G143-Y147 VanDerWaalsContact O-CB 3.27Å; G143-Y147 WeakPolarHBondContact O-CB 3.32Å; G143-Y147 PolarHBondContact O-N 3.31Å
144	V	90.5	Very high	91.1	Very high	1 Å²	1	14 Å²	14	1%	0.006	7%	0.068	C	C	.	.	H	α-helix	trans	-65.6	-43.9	177.6	-170.3	0	0	0	0	111.5	V68 Y141 M142 Y147 T148 T402 V409 V412 I416	V68-V144 HydrophobicContact CG2-CG1 3.88Å; Y141-V144 WeakPolarHBondContact O-CB 3.27Å; Y141-V144 PolarHBondContact O-N 3.13Å; Y141-V144 VanDerWaalsContact O-N 3.07Å; M142-V144 VanDerWaalsContact C-N 3.25Å; M142-V144 PolarHBondContact O-N 2.84Å; V144-Y147 PolarHBondContact O-N 3.27Å; V144-T148 WeakPolarHBondContact O-CB 3.41Å; V144-T148 PolarHBondContact O-N 3.12Å; V144-T148 VanDerWaalsContact O-N 3.13Å; V144-T148 PolarHBondContact O-OG1 3.22Å; V144-T402 HydrophobicContact CB-CG2 4.24Å; V144-T402 HydrophobicContact CG1-CG2 4.24Å; V144-T402 HydrophobicContact CG2-CG2 3.99Å; V144-T402 PolarHBondContact N-OG1 3.37Å; V144-V409 HydrophobicContact CG1-CB 4.12Å; V144-V409 HydrophobicContact CG1-CG1 4.49Å; V144-V412 HydrophobicContact CG2-CG1 3.94Å; V144-I416 HydrophobicContact CG2-CD1 3.93Å
145	C	90.6	Very high	90.4	Very high	1 Å²	1	16.5 Å²	16.5	1%	0.007	9%	0.088	C	C	.	.	H	α-helix	trans	-65.4	-37.6	179.8	-68.6	0	0	0	0	113.7	Y141 M142 P149 T351 I352	Y141-C145 VanDerWaalsContact CE1-SG 3.51Å; Y141-C145 VanDerWaalsContact CE2-SG 3.51Å; Y141-C145 PolarHBondContact O-N 3.26Å; Y141-C145 PolarHBondContact O-SG 3.34Å; M142-C145 HydrophobicContact CE-CB 4.4Å; M142-C145 PolarHBondContact O-N 3.33Å; C145-P149 WeakPolarHBondContact O-CD 3.19Å; C145-T351 HydrophobicContact CB-CG2 4.36Å; C145-T351 VanDerWaalsContact SG-CG2 3.55Å; C145-I352 HydrophobicContact CB-CG1 4.06Å
146	V	89.8	Confident	89.7	Confident	1 Å²	1	15.9 Å²	15.9	1%	0.006	9%	0.086	C	C	.	.	H	α-helix	trans	-74.9	-39.2	177.9	176.4	0	0	0	0	111.2	M142 P149 V165 I352 A399	M142-V146 VanDerWaalsContact O-CG2 3.31Å; M142-V146 WeakPolarHBondContact O-CG2 3.44Å; M142-V146 PolarHBondContact O-N 3.26Å; V146-P149 WeakPolarHBondContact O-CD 3.23Å; V146-V165 HydrophobicContact CG1-CB 4.46Å; V146-V165 HydrophobicContact CG1-CG1 3.85Å; V146-I352 HydrophobicContact CB-CD1 4.37Å; V146-I352 HydrophobicContact CG2-CD1 3.49Å; V146-I352 VanDerWaalsContact CG2-CD1 3.49Å; V146-I352 HydrophobicContact CG2-CG1 4.01Å; V146-A399 HydrophobicContact CB-CB 4.49Å; V146-A399 HydrophobicContact CG1-CB 4.45Å
147	Y	89.3	Confident	89.2	Confident	16 Å²	16	11.8 Å²	11.8	6%	0.063	7%	0.07	C	C	.	.	H	α-helix	trans	-64.3	-43	-179.8	173.7	-103.7	0	0	0	112.6	G143 V144 A150 F151 L161 T402 H403 V409	G143-Y147 VanDerWaalsContact O-CB 3.27Å; G143-Y147 WeakPolarHBondContact O-CB 3.32Å; G143-Y147 PolarHBondContact O-N 3.31Å; V144-Y147 PolarHBondContact O-N 3.27Å; Y147-A150 PolarHBondContact O-N 3.02Å; Y147-F151 HydrophobicContact CD1-CB 4.47Å; Y147-F151 HydrophobicContact CE1-CB 4.03Å; Y147-F151 HydrophobicContact CE1-CG 4.35Å; Y147-F151 HydrophobicContact CE2-CB 4.41Å; Y147-F151 WeakPolarHBondContact O-CB 3.32Å; Y147-F151 PolarHBondContact O-N 3.29Å; Y147-L161 HydrophobicContact CE2-CD1 4.42Å; Y147-L161 HydrophobicContact CE2-CD2 4.13Å; Y147-T402 HydrophobicContact CD1-CG2 3.74Å; Y147-T402 HydrophobicContact CE1-CG2 4.45Å; Y147-T402 HydrophobicContact CG-CG2 4.06Å; Y147-H403 HydrophobicContact CD2-CB 4.17Å; Y147-H403 HydrophobicContact CE2-CB 3.67Å; Y147-H403 AromaticContact CE2-ND1 3.82Å; Y147-H403 AromaticContact CZ-ND1 3.91Å; Y147-H403 PolarHBondContact OH-ND1 2.88Å; Y147-V409 HydrophobicContact CD1-CG1 4.4Å; Y147-V409 HydrophobicContact CE1-CG1 4.49Å
148	T	89.8	Confident	88.5	Confident	1 Å²	1	13.9 Å²	13.9	1%	0.006	9%	0.091	C	C	.	.	H	α-helix	trans	-56.6	-53.3	-171.7	-59.3	0	0	0	0	115.2	A67 V68 I71 V144 A150 F151 A152 V409	A67-T148 HydrophobicContact CB-CG2 3.81Å; V68-T148 HydrophobicContact CG2-CG2 4.43Å; V68-T148 WeakPolarHBondContact CG2-OG1 3.26Å; I71-T148 HydrophobicContact CD1-CG2 3.76Å; V144-T148 WeakPolarHBondContact O-CB 3.41Å; V144-T148 PolarHBondContact O-N 3.12Å; V144-T148 VanDerWaalsContact O-N 3.13Å; V144-T148 PolarHBondContact O-OG1 3.22Å; T148-A150 VanDerWaalsContact C-N 3.3Å; T148-A150 PolarHBondContact O-N 3.22Å; T148-F151 PolarHBondContact O-N 3.3Å; T148-A152 PolarHBondContact O-N 3Å; T148-V409 HydrophobicContact CG2-CG2 4.28Å
149	P	90	Very high	88	Confident	0 Å²	0	18.2 Å²	18.2	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-67.9	-31.1	177.9	30.6	-39.3	0	0	0	112.3	C145 V146 A152 L153 F345 A348	C145-P149 WeakPolarHBondContact O-CD 3.19Å; V146-P149 WeakPolarHBondContact O-CD 3.23Å; P149-A152 PolarHBondContact O-N 2.96Å; P149-L153 PolarHBondContact O-N 3.34Å; P149-F345 HydrophobicContact CB-CD2 3.83Å; P149-F345 HydrophobicContact CB-CE2 3.86Å; P149-F345 HydrophobicContact CB-CG 4.27Å; P149-F345 HydrophobicContact CB-CZ 4.32Å; P149-A348 HydrophobicContact CB-CB 4.16Å; P149-A348 HydrophobicContact CG-CB 3.57Å
150	A	90.2	Very high	87.8	Confident	0 Å²	0	24 Å²	24	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-69.1	-41.3	177.2	0	0	0	0	0	111.7	Y147 T148 A152 L153 N154 L161 T164 V165	Y147-A150 PolarHBondContact O-N 3.02Å; T148-A150 VanDerWaalsContact C-N 3.3Å; T148-A150 PolarHBondContact O-N 3.22Å; A150-A152 VanDerWaalsContact C-N 3.33Å; A150-L153 PolarHBondContact O-N 3.06Å; A150-N154 WeakPolarHBondContact O-CB 3.34Å; A150-N154 PolarHBondContact O-N 2.94Å; A150-L161 VanDerWaalsContact C-CD1 3.41Å; A150-L161 HydrophobicContact CB-CD1 3.83Å; A150-L161 WeakPolarHBondContact O-CD1 3.45Å; A150-T164 HydrophobicContact CB-CG2 3.71Å; A150-V165 HydrophobicContact CB-CB 4.45Å; A150-V165 HydrophobicContact CB-CG2 3.42Å; A150-V165 VanDerWaalsContact CB-CG2 3.42Å
151	F	87.5	Confident	87.6	Confident	23 Å²	23	23 Å²	23	10%	0.101	13%	0.132	C	C	.	.	H	α-helix	trans	-58.2	-46.1	170.1	168.3	-101.6	0	0	0	111.2	Y147 T148 L153 N154 A155 L161 D319 A320	Y147-F151 HydrophobicContact CD1-CB 4.47Å; Y147-F151 HydrophobicContact CE1-CB 4.03Å; Y147-F151 HydrophobicContact CE1-CG 4.35Å; Y147-F151 HydrophobicContact CE2-CB 4.41Å; Y147-F151 WeakPolarHBondContact O-CB 3.32Å; Y147-F151 PolarHBondContact O-N 3.29Å; T148-F151 PolarHBondContact O-N 3.3Å; F151-L153 PolarHBondContact O-N 3.44Å; F151-N154 PolarHBondContact O-N 3.2Å; F151-A155 WeakPolarHBondContact O-CB 3.36Å; F151-A155 PolarHBondContact O-N 3.25Å; F151-L161 HydrophobicContact CB-CD1 4.46Å; F151-D319 HydrophobicContact CE1-CB 4.06Å; F151-A320 HydrophobicContact CZ-CB 3.96Å
152	A	87.8	Confident	87.3	Confident	1 Å²	1	27 Å²	27	1%	0.008	15%	0.147	C	C	.	.	H	α-helix	trans	-61.7	-45.1	178.1	0	0	0	0	0	112.8	I71 T148 P149 A150 A155 A156 I323 L344	I71-A152 HydrophobicContact CD1-CB 3.95Å; T148-A152 PolarHBondContact O-N 3Å; P149-A152 PolarHBondContact O-N 2.96Å; A150-A152 VanDerWaalsContact C-N 3.33Å; A152-A155 PolarHBondContact O-N 3.15Å; A152-A156 WeakPolarHBondContact O-CB 3.29Å; A152-A156 PolarHBondContact O-N 2.76Å; A152-I323 HydrophobicContact CB-CD1 3.52Å; A152-I323 HydrophobicContact CB-CG1 4.11Å; A152-L344 HydrophobicContact CB-CD1 3.43Å; A152-L344 VanDerWaalsContact CB-CD1 3.43Å
153	L	88.4	Confident	87.1	Confident	11 Å²	11	27.8 Å²	27.8	6%	0.058	16%	0.155	C	C	.	.	H	α-helix	trans	-65.2	-42.3	177.5	-179.2	63.9	0	0	0	111.6	P149 A150 F151 A156 T157 F159 T164 V341 F345	P149-L153 PolarHBondContact O-N 3.34Å; A150-L153 PolarHBondContact O-N 3.06Å; F151-L153 PolarHBondContact O-N 3.44Å; L153-A156 PolarHBondContact O-N 3.46Å; L153-T157 HydrophobicContact CD1-CG2 3.73Å; L153-T157 PolarHBondContact O-N 2.82Å; L153-T157 PolarHBondContact O-OG1 3.23Å; L153-F159 HydrophobicContact CG-CB 4.33Å; L153-T164 HydrophobicContact CB-CG2 4.35Å; L153-T164 HydrophobicContact CD2-CG2 3.65Å; L153-V341 HydrophobicContact CD1-CG1 3.97Å; L153-F345 HydrophobicContact CB-CE2 4.1Å; L153-F345 HydrophobicContact CB-CZ 4.31Å; L153-F345 HydrophobicContact CD2-CE2 4.39Å; L153-F345 HydrophobicContact CD2-CZ 4Å
154	N	87.8	Confident	86.9	Confident	56 Å²	56	28 Å²	28	30%	0.299	16%	0.156	S	C	.	.	H	α-helix	trans	-61	-45.3	175.9	173.9	-110.9	0	0	0	111.3	A150 F151 A156 G158 F159 L161	A150-N154 WeakPolarHBondContact O-CB 3.34Å; A150-N154 PolarHBondContact O-N 2.94Å; F151-N154 PolarHBondContact O-N 3.2Å; N154-A156 VanDerWaalsContact C-N 3.32Å; N154-A156 PolarHBondContact O-N 3.49Å; N154-G158 VanDerWaalsContact O-CA 3.23Å; N154-G158 WeakPolarHBondContact O-CA 3.14Å; N154-G158 PolarHBondContact O-N 2.85Å; N154-F159 WeakPolarHBondContact CB-O 3.4Å; N154-F159 PolarHBondContact ND2-O 3.23Å; N154-L161 HydrophobicContact CB-CB 4.25Å; N154-L161 HydrophobicContact CB-CD1 4.22Å
155	A	82.3	Confident	86.8	Confident	52 Å²	52	28 Å²	28	43%	0.43	16%	0.156	S	C	.	.	H	α-helix	trans	-66.9	-32	177.4	0	0	0	0	0	113.1	F151 A152 I323	F151-A155 WeakPolarHBondContact O-CB 3.36Å; F151-A155 PolarHBondContact O-N 3.25Å; A152-A155 PolarHBondContact O-N 3.15Å; A155-I323 HydrophobicContact CB-CB 4.37Å; A155-I323 HydrophobicContact CB-CG2 3.93Å
156	A	82.6	Confident	86.5	Confident	8 Å²	8	32.7 Å²	32.7	7%	0.066	18%	0.181	C	C	.	.	H	α-helix	trans	-80.1	-37.6	-179.9	0	0	0	0	0	114.1	F9 A152 L153 N154 I323 M327	F9-A156 HydrophobicContact CE1-CB 4.36Å; A152-A156 WeakPolarHBondContact O-CB 3.29Å; A152-A156 PolarHBondContact O-N 2.76Å; L153-A156 PolarHBondContact O-N 3.46Å; N154-A156 VanDerWaalsContact C-N 3.32Å; N154-A156 PolarHBondContact O-N 3.49Å; A156-I323 HydrophobicContact CB-CG2 4.03Å; A156-M327 HydrophobicContact CB-CE 3.54Å; A156-M327 HydrophobicContact CB-CG 4.11Å; A156-M327 HydrophobicContact CB-SD 3.89Å
157	T	83.1	Confident	86.2	Confident	12 Å²	12	37.1 Å²	37.1	7%	0.074	20%	0.203	C	C	.	.	H	α-helix	trans	-123	-13.1	-167.7	63	0	0	0	0	114.3	F9 L153 F159	F9-T157 HydrophobicContact CB-CG2 4.15Å; F9-T157 HydrophobicContact CD1-CG2 3.49Å; F9-T157 VanDerWaalsContact CD1-CG2 3.49Å; F9-T157 HydrophobicContact CD2-CG2 3.81Å; F9-T157 HydrophobicContact CE1-CG2 3.82Å; F9-T157 HydrophobicContact CE2-CG2 4.12Å; F9-T157 HydrophobicContact CG-CG2 3.52Å; F9-T157 HydrophobicContact CZ-CG2 4.14Å; L153-T157 HydrophobicContact CD1-CG2 3.73Å; L153-T157 PolarHBondContact O-N 2.82Å; L153-T157 PolarHBondContact O-OG1 3.23Å; T157-F159 PolarHBondContact O-N 3.4Å; T157-F159 VanDerWaalsContact OG1-CB 3.26Å; T157-F159 WeakPolarHBondContact OG1-CB 3.37Å; T157-F159 PolarHBondContact OG1-N 2.98Å
158	G	80.7	Confident	85.8	Confident	46 Å²	46	36.5 Å²	36.5	47%	0.474	20%	0.201	S	C	.	.			trans	75.7	3.4	-169.2	0	0	0	0	0	114.1	N154	N154-G158 VanDerWaalsContact O-CA 3.23Å; N154-G158 WeakPolarHBondContact O-CA 3.14Å; N154-G158 PolarHBondContact O-N 2.85Å
159	F	83.3	Confident	85.4	Confident	94 Å²	94	36.6 Å²	36.6	41%	0.412	20%	0.203	S	C	.	.			trans	-61.2	149.1	-178.8	-160	-91.3	0	0	0	112.2	L153 N154 T157 L161 T164	L153-F159 HydrophobicContact CG-CB 4.33Å; N154-F159 WeakPolarHBondContact CB-O 3.4Å; N154-F159 PolarHBondContact ND2-O 3.23Å; T157-F159 PolarHBondContact O-N 3.4Å; T157-F159 VanDerWaalsContact OG1-CB 3.26Å; T157-F159 WeakPolarHBondContact OG1-CB 3.37Å; T157-F159 PolarHBondContact OG1-N 2.98Å; F159-L161 PolarHBondContact O-N 3.38Å; F159-L161 VanDerWaalsContact O-N 3.09Å; F159-T164 VanDerWaalsContact CD1-OG1 3.27Å; F159-T164 WeakPolarHBondContact CD1-OG1 3.29Å
160	Q	88.3	Confident	85	Confident	134 Å²	134	41.7 Å²	41.7	63%	0.626	23%	0.229	S	C	*	.			trans	-62	114.1	-175.4	-171.4	-173	10.3	0	0	112	W162 G163 T164	Q160-W162 PolarHBondContact O-N 3.02Å; Q160-G163 PolarHBondContact O-N 3.46Å; Q160-G163 VanDerWaalsContact O-N 3.12Å; Q160-T164 PolarHBondContact O-N 3.48Å; Q160-T164 PolarHBondContact O-OG1 3.48Å
161	L	85	Confident	84.6	Confident	21 Å²	21	43.8 Å²	43.8	11%	0.11	24%	0.242	C	C	.	.	H	α-helix	trans	-49.4	-52.4	-178.1	178.5	66.8	0	0	0	113.2	Y147 A150 F151 N154 F159 G163 T164 V165	Y147-L161 HydrophobicContact CE2-CD1 4.42Å; Y147-L161 HydrophobicContact CE2-CD2 4.13Å; A150-L161 VanDerWaalsContact C-CD1 3.41Å; A150-L161 HydrophobicContact CB-CD1 3.83Å; A150-L161 WeakPolarHBondContact O-CD1 3.45Å; F151-L161 HydrophobicContact CB-CD1 4.46Å; N154-L161 HydrophobicContact CB-CB 4.25Å; N154-L161 HydrophobicContact CB-CD1 4.22Å; F159-L161 PolarHBondContact O-N 3.38Å; F159-L161 VanDerWaalsContact O-N 3.09Å; L161-G163 PolarHBondContact O-N 3.43Å; L161-T164 WeakPolarHBondContact O-CB 3.4Å; L161-T164 PolarHBondContact O-N 3.38Å; L161-V165 WeakPolarHBondContact O-CG2 3.21Å; L161-V165 PolarHBondContact O-N 3.38Å
162	W	86.9	Confident	84.2	Confident	90 Å²	90	42.7 Å²	42.7	34%	0.341	24%	0.237	S	C	.	.	H	α-helix	trans	-67	-35.2	-177.7	-63.5	112.1	0	0	0	113	Q160 T164 V165 L166 Y400	Q160-W162 PolarHBondContact O-N 3.02Å; W162-T164 VanDerWaalsContact C-N 3.33Å; W162-V165 PolarHBondContact O-N 3.46Å; W162-L166 WeakPolarHBondContact O-CB 3.41Å; W162-L166 VanDerWaalsContact O-CG 3.3Å; W162-L166 WeakPolarHBondContact O-CG 3.33Å; W162-L166 PolarHBondContact O-N 2.91Å; W162-Y400 AromaticContact CH2-CD2 3.33Å; W162-Y400 HydrophobicContact CH2-CD2 3.33Å; W162-Y400 HydrophobicContact CH2-CE2 4.27Å; W162-Y400 HydrophobicContact CH2-CG 4Å; W162-Y400 AromaticContact CZ2-CD2 3.52Å; W162-Y400 HydrophobicContact CZ2-CD2 3.52Å; W162-Y400 HydrophobicContact CZ2-CE2 4.02Å; W162-Y400 HydrophobicContact CZ3-CD2 4.1Å
163	G	85.3	Confident	83.9	Confident	16 Å²	16	43.2 Å²	43.2	17%	0.165	24%	0.24	C	C	.	.	H	α-helix	trans	-61.7	-43.7	173.1	0	0	0	0	0	111.1	Q160 L161 L166 I167	Q160-G163 PolarHBondContact O-N 3.46Å; Q160-G163 VanDerWaalsContact O-N 3.12Å; L161-G163 PolarHBondContact O-N 3.43Å; G163-L166 PolarHBondContact O-N 3.48Å; G163-I167 WeakPolarHBondContact O-CB 3.48Å; G163-I167 WeakPolarHBondContact O-CD1 3.33Å; G163-I167 VanDerWaalsContact O-CG1 3.24Å; G163-I167 WeakPolarHBondContact O-CG1 3.36Å; G163-I167 PolarHBondContact O-N 3.44Å
164	T	86.6	Confident	83.4	Confident	4 Å²	4	46.9 Å²	46.9	3%	0.025	26%	0.26	C	S	.	.	H	α-helix	trans	-64.6	-43.8	175.5	-54	0	0	0	0	112.9	A150 L153 F159 Q160 L161 W162 L166 I167 T168 F345	A150-T164 HydrophobicContact CB-CG2 3.71Å; L153-T164 HydrophobicContact CB-CG2 4.35Å; L153-T164 HydrophobicContact CD2-CG2 3.65Å; F159-T164 VanDerWaalsContact CD1-OG1 3.27Å; F159-T164 WeakPolarHBondContact CD1-OG1 3.29Å; Q160-T164 PolarHBondContact O-N 3.48Å; Q160-T164 PolarHBondContact O-OG1 3.48Å; L161-T164 WeakPolarHBondContact O-CB 3.4Å; L161-T164 PolarHBondContact O-N 3.38Å; W162-T164 VanDerWaalsContact C-N 3.33Å; T164-L166 VanDerWaalsContact C-N 3.33Å; T164-L166 PolarHBondContact O-N 3.49Å; T164-I167 PolarHBondContact O-N 3.25Å; T164-T168 WeakPolarHBondContact O-CB 3.47Å; T164-T168 PolarHBondContact O-N 3.26Å; T164-T168 PolarHBondContact O-OG1 3.22Å; T164-F345 HydrophobicContact CG2-CE1 4.05Å; T164-F345 HydrophobicContact CG2-CZ 3.49Å; T164-F345 VanDerWaalsContact CG2-CZ 3.49Å
165	V	87	Confident	82.9	Confident	2 Å²	2	44.3 Å²	44.3	1%	0.012	25%	0.246	C	C	.	.	H	α-helix	trans	-57	-47.9	175.7	165.2	0	0	0	0	110.4	V146 A150 L161 W162 T168 G169 L396 A399	V146-V165 HydrophobicContact CG1-CB 4.46Å; V146-V165 HydrophobicContact CG1-CG1 3.85Å; A150-V165 HydrophobicContact CB-CB 4.45Å; A150-V165 HydrophobicContact CB-CG2 3.42Å; A150-V165 VanDerWaalsContact CB-CG2 3.42Å; L161-V165 WeakPolarHBondContact O-CG2 3.21Å; L161-V165 PolarHBondContact O-N 3.38Å; W162-V165 PolarHBondContact O-N 3.46Å; V165-T168 PolarHBondContact O-N 3.25Å; V165-G169 PolarHBondContact O-N 3.38Å; V165-L396 HydrophobicContact CG1-CD2 3.57Å; V165-L396 WeakPolarHBondContact O-CD2 3.46Å; V165-A399 HydrophobicContact CG1-CB 4.09Å
166	L	84.6	Confident	82.6	Confident	99 Å²	99	42 Å²	42	52%	0.518	23%	0.226	S	C	.	.	H	α-helix	trans	-61.4	-48.9	177.9	-73.6	171.5	0	0	0	112.4	W162 G163 T164 T168 G169 L170 L396	W162-L166 WeakPolarHBondContact O-CB 3.41Å; W162-L166 VanDerWaalsContact O-CG 3.3Å; W162-L166 WeakPolarHBondContact O-CG 3.33Å; W162-L166 PolarHBondContact O-N 2.91Å; G163-L166 PolarHBondContact O-N 3.48Å; T164-L166 VanDerWaalsContact C-N 3.33Å; T164-L166 PolarHBondContact O-N 3.49Å; L166-T168 PolarHBondContact O-N 3.37Å; L166-G169 PolarHBondContact O-N 3.29Å; L166-L170 VanDerWaalsContact O-CB 3.27Å; L166-L170 WeakPolarHBondContact O-CB 3.42Å; L166-L170 PolarHBondContact O-N 2.69Å; L166-L396 HydrophobicContact CD2-CD1 3.71Å; L166-L396 HydrophobicContact CD2-CD2 4.18Å
167	I	83.4	Confident	82.2	Confident	93 Å²	93	42.2 Å²	42.2	48%	0.477	23%	0.226	S	C	.	.	H	α-helix	trans	-62.5	-45.3	-179.8	-69	164.7	0	0	0	110.6	G163 T164 L170 V171	G163-I167 WeakPolarHBondContact O-CB 3.48Å; G163-I167 WeakPolarHBondContact O-CD1 3.33Å; G163-I167 VanDerWaalsContact O-CG1 3.24Å; G163-I167 WeakPolarHBondContact O-CG1 3.36Å; G163-I167 PolarHBondContact O-N 3.44Å; T164-I167 PolarHBondContact O-N 3.25Å; I167-L170 PolarHBondContact O-N 3.44Å; I167-V171 HydrophobicContact CG2-CG2 4.19Å; I167-V171 WeakPolarHBondContact O-CB 3.47Å; I167-V171 VanDerWaalsContact O-CG2 3.26Å; I167-V171 WeakPolarHBondContact O-CG2 3.48Å; I167-V171 PolarHBondContact O-N 2.82Å
168	T	82.4	Confident	81.8	Confident	3 Å²	3	45 Å²	45	2%	0.018	24%	0.241	C	C	.	.	H	α-helix	trans	-62.1	-47.1	179.8	-51.4	0	0	0	0	111	T164 V165 L166 C172 F345 L349	T164-T168 WeakPolarHBondContact O-CB 3.47Å; T164-T168 PolarHBondContact O-N 3.26Å; T164-T168 PolarHBondContact O-OG1 3.22Å; V165-T168 PolarHBondContact O-N 3.25Å; L166-T168 PolarHBondContact O-N 3.37Å; T168-C172 VanDerWaalsContact O-CB 3.26Å; T168-C172 WeakPolarHBondContact O-CB 3.5Å; T168-C172 PolarHBondContact O-N 3.4Å; T168-F345 HydrophobicContact CG2-CD1 4.25Å; T168-F345 HydrophobicContact CG2-CE1 4.27Å; T168-F345 WeakPolarHBondContact OG1-CE1 3.48Å; T168-L349 HydrophobicContact CG2-CD2 4.1Å
169	G	81.1	Confident	81.5	Confident	4 Å²	4	43 Å²	43	4%	0.041	22%	0.22	C	C	.	.	H	α-helix	trans	-61.4	-44.5	176.8	0	0	0	0	0	112.2	V165 L166 T173	V165-G169 PolarHBondContact O-N 3.38Å; L166-G169 PolarHBondContact O-N 3.29Å; G169-T173 VanDerWaalsContact O-CB 3.25Å; G169-T173 WeakPolarHBondContact O-CB 3.1Å; G169-T173 PolarHBondContact O-N 3.29Å; G169-T173 PolarHBondContact O-OG1 3.42Å
170	L	80.6	Confident	81.4	Confident	106 Å²	106	38.6 Å²	38.6	56%	0.555	20%	0.201	S	C	*	.	H	α-helix	trans	-64.3	-51.3	179	-178.1	64.8	0	0	0	111.7	L166 I167 C172 T173 L174	L166-L170 VanDerWaalsContact O-CB 3.27Å; L166-L170 WeakPolarHBondContact O-CB 3.42Å; L166-L170 PolarHBondContact O-N 2.69Å; I167-L170 PolarHBondContact O-N 3.44Å; L170-C172 VanDerWaalsContact C-N 3.32Å; L170-C172 PolarHBondContact O-N 3.21Å; L170-T173 PolarHBondContact O-N 3.45Å; L170-L174 HydrophobicContact CD1-CD1 4.14Å; L170-L174 HydrophobicContact CD1-CG 4.22Å; L170-L174 HydrophobicContact CG-CD1 3.93Å; L170-L174 HydrophobicContact CG-CG 4.4Å; L170-L174 WeakPolarHBondContact O-CB 3.1Å; L170-L174 VanDerWaalsContact O-CG 3.27Å; L170-L174 WeakPolarHBondContact O-CG 3.09Å; L170-L174 PolarHBondContact O-N 2.79Å
171	V	82	Confident	81.3	Confident	44 Å²	44	32.3 Å²	32.3	27%	0.267	17%	0.172	S	C	.	.	H	α-helix	trans	-57.7	-47.8	178.9	170	0	0	0	0	110.3	V25 I167 T173 L174 Y175	V25-V171 HydrophobicContact CG2-CG1 3.5Å; I167-V171 HydrophobicContact CG2-CG2 4.19Å; I167-V171 WeakPolarHBondContact O-CB 3.47Å; I167-V171 VanDerWaalsContact O-CG2 3.26Å; I167-V171 WeakPolarHBondContact O-CG2 3.48Å; I167-V171 PolarHBondContact O-N 2.82Å; V171-T173 PolarHBondContact O-N 2.98Å; V171-L174 PolarHBondContact O-N 3.44Å; V171-Y175 HydrophobicContact CG1-CD1 4.34Å; V171-Y175 WeakPolarHBondContact O-CD1 3.12Å; V171-Y175 PolarHBondContact O-N 3.48Å
172	C	79.6	Confident	81.4	Confident	0 Å²	0	34.7 Å²	34.7	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-60.7	-45.1	178.3	-166.4	0	0	0	0	112.4	T168 L170 L174 Y175 T176 L349 I352 S353	T168-C172 VanDerWaalsContact O-CB 3.26Å; T168-C172 WeakPolarHBondContact O-CB 3.5Å; T168-C172 PolarHBondContact O-N 3.4Å; L170-C172 VanDerWaalsContact C-N 3.32Å; L170-C172 PolarHBondContact O-N 3.21Å; C172-L174 PolarHBondContact O-N 3.36Å; C172-Y175 HydrophobicContact CB-CE1 4.35Å; C172-T176 WeakPolarHBondContact O-CB 3.41Å; C172-T176 PolarHBondContact O-N 2.71Å; C172-T176 VanDerWaalsContact O-N 3.09Å; C172-T176 PolarHBondContact O-OG1 3.46Å; C172-L349 HydrophobicContact CB-CD2 3.65Å; C172-I352 HydrophobicContact CB-CG2 4.12Å; C172-I352 VanDerWaalsContact SG-CB 3.56Å; C172-I352 WeakPolarHBondContact SG-CG2 3.35Å; C172-S353 PolarHBondContact SG-N 3.24Å
173	T	80.8	Confident	81.3	Confident	12 Å²	12	30.5 Å²	30.5	7%	0.074	17%	0.165	C	C	.	.	H	α-helix	trans	-61	-46.2	178.5	-60.4	0	0	0	0	110.9	G169 L170 V171 T176 T177 T389	G169-T173 VanDerWaalsContact O-CB 3.25Å; G169-T173 WeakPolarHBondContact O-CB 3.1Å; G169-T173 PolarHBondContact O-N 3.29Å; G169-T173 PolarHBondContact O-OG1 3.42Å; L170-T173 PolarHBondContact O-N 3.45Å; V171-T173 PolarHBondContact O-N 2.98Å; T173-T176 PolarHBondContact O-N 2.95Å; T173-T177 HydrophobicContact CG2-CG2 4Å; T173-T177 VanDerWaalsContact O-CB 3.28Å; T173-T177 WeakPolarHBondContact O-CB 3.35Å; T173-T177 WeakPolarHBondContact O-CG2 3.48Å; T173-T177 PolarHBondContact O-N 2.79Å; T173-T177 PolarHBondContact O-OG1 3.07Å; T173-T389 HydrophobicContact CG2-CG2 4.06Å
174	L	78.3	Confident	81.5	Confident	89 Å²	89	29.7 Å²	29.7	47%	0.466	16%	0.158	S	C	.	.	H	α-helix	trans	-60.7	-55.2	-177.8	-73.5	171.6	0	0	0	112.1	L170 V171 C172 T176 T177 L178	L170-L174 HydrophobicContact CD1-CD1 4.14Å; L170-L174 HydrophobicContact CD1-CG 4.22Å; L170-L174 HydrophobicContact CG-CD1 3.93Å; L170-L174 HydrophobicContact CG-CG 4.4Å; L170-L174 WeakPolarHBondContact O-CB 3.1Å; L170-L174 VanDerWaalsContact O-CG 3.27Å; L170-L174 WeakPolarHBondContact O-CG 3.09Å; L170-L174 PolarHBondContact O-N 2.79Å; V171-L174 PolarHBondContact O-N 3.44Å; C172-L174 PolarHBondContact O-N 3.36Å; L174-T176 VanDerWaalsContact C-N 3.33Å; L174-T176 PolarHBondContact O-N 3.38Å; L174-T177 PolarHBondContact O-OG1 2.95Å; L174-L178 VanDerWaalsContact O-CB 3.29Å; L174-L178 WeakPolarHBondContact O-CB 3.33Å; L174-L178 WeakPolarHBondContact O-CG 3.15Å; L174-L178 PolarHBondContact O-N 3.2Å
175	Y	77.1	Confident	81.7	Confident	2 Å²	2	29.5 Å²	29.5	1%	0.008	16%	0.156	C	C	.	.	H	α-helix	trans	-72.9	-27.4	-177.3	78.5	-104	0	0	0	112.8	V171 C172 G179 L349 S353	V171-Y175 HydrophobicContact CG1-CD1 4.34Å; V171-Y175 WeakPolarHBondContact O-CD1 3.12Å; V171-Y175 PolarHBondContact O-N 3.48Å; C172-Y175 HydrophobicContact CB-CE1 4.35Å; Y175-G179 WeakPolarHBondContact O-CA 3.47Å; Y175-G179 PolarHBondContact O-N 3.02Å; Y175-L349 HydrophobicContact CE1-CD2 4.2Å; Y175-L349 WeakPolarHBondContact OH-CB 3.5Å; Y175-L349 PolarHBondContact OH-O 3.46Å; Y175-S353 WeakPolarHBondContact OH-CB 3.38Å
176	T	76.3	Confident	81.9	Confident	2 Å²	2	33.8 Å²	33.8	1%	0.012	17%	0.172	C	C	.	.	H	α-helix	trans	-70.7	-44	177.3	-55.9	0	0	0	0	111.1	C172 T173 L174 L178 G180 V184 S353 F356	C172-T176 WeakPolarHBondContact O-CB 3.41Å; C172-T176 PolarHBondContact O-N 2.71Å; C172-T176 VanDerWaalsContact O-N 3.09Å; C172-T176 PolarHBondContact O-OG1 3.46Å; T173-T176 PolarHBondContact O-N 2.95Å; L174-T176 VanDerWaalsContact C-N 3.33Å; L174-T176 PolarHBondContact O-N 3.38Å; T176-L178 VanDerWaalsContact C-N 3.33Å; T176-G180 PolarHBondContact O-N 3.3Å; T176-V184 HydrophobicContact CG2-CG2 4.28Å; T176-S353 WeakPolarHBondContact OG1-CA 3.46Å; T176-S353 VanDerWaalsContact OG1-CB 3.24Å; T176-S353 WeakPolarHBondContact OG1-CB 3.45Å; T176-F356 HydrophobicContact CG2-CB 4.04Å
177	T	74.9	Confident	82.2	Confident	13 Å²	13	29 Å²	29	8%	0.08	15%	0.147	C	C	.	.	H	α-helix	trans	-67.7	-35.3	177.4	56.1	0	0	0	0	111.8	F44 T173 L174 K385 A388 T389	F44-T177 WeakPolarHBondContact CE2-O 3.48Å; T173-T177 HydrophobicContact CG2-CG2 4Å; T173-T177 VanDerWaalsContact O-CB 3.28Å; T173-T177 WeakPolarHBondContact O-CB 3.35Å; T173-T177 WeakPolarHBondContact O-CG2 3.48Å; T173-T177 PolarHBondContact O-N 2.79Å; T173-T177 PolarHBondContact O-OG1 3.07Å; L174-T177 PolarHBondContact O-OG1 2.95Å; T177-K385 WeakPolarHBondContact O-CD 3.49Å; T177-K385 WeakPolarHBondContact O-CE 3.28Å; T177-K385 WeakPolarHBondContact O-CG 3.39Å; T177-A388 HydrophobicContact CG2-CB 3.69Å; T177-T389 WeakPolarHBondContact CG2-OG1 3.46Å
178	L	72.8	Confident	82.6	Confident	72 Å²	72	24.6 Å²	24.6	38%	0.377	13%	0.125	S	C	.	.	H	α-helix	trans	-81.6	-30.8	179.6	-66.3	174.2	0	0	0	113.1	L29 A32 Q38 L174 T176	L29-L178 HydrophobicContact CD2-CD1 3.68Å; A32-L178 HydrophobicContact CB-CB 3.96Å; A32-L178 WeakPolarHBondContact CB-O 3.08Å; Q38-L178 PolarHBondContact NE2-O 3.07Å; Q38-L178 PolarHBondContact OE1-O 3.18Å; L174-L178 VanDerWaalsContact O-CB 3.29Å; L174-L178 WeakPolarHBondContact O-CB 3.33Å; L174-L178 WeakPolarHBondContact O-CG 3.15Å; L174-L178 PolarHBondContact O-N 3.2Å; T176-L178 VanDerWaalsContact C-N 3.33Å
179	G	74.9	Confident	83.2	Confident	4 Å²	4	25.6 Å²	25.6	4%	0.041	13%	0.131	C	C	.	.	H	α-helix	trans	-100.8	-25.5	-167.1	0	0	0	0	0	117	Q38 Y175 A183	Q38-G179 PolarHBondContact NE2-O 2.87Å; Y175-G179 WeakPolarHBondContact O-CA 3.47Å; Y175-G179 PolarHBondContact O-N 3.02Å; G179-A183 VanDerWaalsContact C-CB 3.42Å; G179-A183 WeakPolarHBondContact O-CB 3.46Å
180	G	82.5	Confident	83.7	Confident	1 Å²	1	27.9 Å²	27.9	1%	0.01	14%	0.139	C	C	.	.	H	α-helix	trans	65.1	-178.1	-175.5	0	0	0	0	0	113.7	F44 T176 K182 A183 V184	F44-G180 VanDerWaalsContact CD2-CA 3.47Å; F44-G180 WeakPolarHBondContact O-CA 3.49Å; T176-G180 PolarHBondContact O-N 3.3Å; G180-K182 VanDerWaalsContact C-N 3.26Å; G180-K182 PolarHBondContact O-N 3.01Å; G180-A183 PolarHBondContact O-N 2.89Å; G180-V184 WeakPolarHBondContact O-CG2 3.26Å; G180-V184 PolarHBondContact O-N 3.47Å; G180-V184 VanDerWaalsContact O-N 3.07Å
181	L	85.2	Confident	84.4	Confident	1 Å²	1	22.8 Å²	22.8	1%	0.005	11%	0.113	C	C	.	.	H	α-helix	trans	-58.7	-36	-171.9	-178.4	65.4	0	0	0	112.8	F44 L45 A47 V184 I185 Q264	F44-L181 PolarHBondContact O-N 3.43Å; L45-L181 VanDerWaalsContact O-CD2 3.3Å; L45-L181 WeakPolarHBondContact O-CD2 2.99Å; A47-L181 HydrophobicContact CB-CB 4.4Å; A47-L181 HydrophobicContact CB-CD2 4.38Å; A47-L181 HydrophobicContact CB-CG 4.42Å; L181-V184 PolarHBondContact O-N 3.17Å; L181-I185 HydrophobicContact CD1-CD1 4.23Å; L181-I185 HydrophobicContact CD1-CG1 4.29Å; L181-I185 HydrophobicContact CD2-CD1 4.39Å; L181-I185 HydrophobicContact CG-CD1 3.92Å; L181-I185 HydrophobicContact CG-CG1 4.4Å; L181-I185 WeakPolarHBondContact O-CG1 3.23Å; L181-I185 PolarHBondContact O-N 2.96Å; L181-Q264 HydrophobicContact CD2-CG 4.04Å
182	K	86.4	Confident	84.9	Confident	72 Å²	72	20.8 Å²	20.8	31%	0.313	10%	0.101	S	C	.	.	H	α-helix	trans	-64	-45.1	-179.9	-170.9	173.1	-175.5	171	0	112.2	A47 M51 G180 I185 W186	A47-K182 HydrophobicContact CB-CB 3.77Å; A47-K182 HydrophobicContact CB-CG 4.42Å; M51-K182 HydrophobicContact SD-CG 4.13Å; G180-K182 VanDerWaalsContact C-N 3.26Å; G180-K182 PolarHBondContact O-N 3.01Å; K182-I185 PolarHBondContact O-N 2.87Å; K182-W186 PolarHBondContact O-N 2.9Å
183	A	86.6	Confident	85.6	Confident	1 Å²	1	25.9 Å²	25.9	1%	0.008	13%	0.128	C	C	.	.	H	α-helix	trans	-64.2	-44.4	175.6	0	0	0	0	0	110.4	G179 G180 I185 W186 T187	G179-A183 VanDerWaalsContact C-CB 3.42Å; G179-A183 WeakPolarHBondContact O-CB 3.46Å; G180-A183 PolarHBondContact O-N 2.89Å; A183-I185 VanDerWaalsContact C-N 3.32Å; A183-I185 PolarHBondContact O-N 3.08Å; A183-W186 PolarHBondContact O-N 3.41Å; A183-W186 VanDerWaalsContact O-N 3.12Å; A183-T187 WeakPolarHBondContact O-CG2 3.37Å; A183-T187 PolarHBondContact O-N 2.74Å; A183-T187 PolarHBondContact O-OG1 2.71Å; A183-T187 VanDerWaalsContact O-OG1 3.1Å
184	V	88.4	Confident	86.3	Confident	0 Å²	0	25.8 Å²	25.8	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-53.8	-47.7	177.1	171.2	0	0	0	0	111.3	T176 G180 L181 W186 T187 D188	T176-V184 HydrophobicContact CG2-CG2 4.28Å; G180-V184 WeakPolarHBondContact O-CG2 3.26Å; G180-V184 PolarHBondContact O-N 3.47Å; G180-V184 VanDerWaalsContact O-N 3.07Å; L181-V184 PolarHBondContact O-N 3.17Å; V184-W186 PolarHBondContact O-N 3.34Å; V184-T187 VanDerWaalsContact CA-OG1 3.3Å; V184-T187 WeakPolarHBondContact CA-OG1 3.17Å; V184-T187 PolarHBondContact O-N 2.7Å; V184-T187 PolarHBondContact O-OG1 2.86Å; V184-D188 WeakPolarHBondContact O-CB 3.41Å; V184-D188 PolarHBondContact O-N 3.44Å
185	I	91.3	Very high	87	Confident	0 Å²	0	21.8 Å²	21.8	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-62.6	-41.2	179.4	-68.8	166.3	0	0	0	111.9	M51 P55 L181 K182 A183 D188 V189	M51-I185 HydrophobicContact CE-CB 3.7Å; M51-I185 HydrophobicContact CE-CD1 3.81Å; M51-I185 HydrophobicContact CE-CG1 4.36Å; M51-I185 HydrophobicContact CE-CG2 3.3Å; M51-I185 HydrophobicContact CG-CD1 3.86Å; M51-I185 HydrophobicContact SD-CD1 4.49Å; P55-I185 HydrophobicContact CB-CG2 3.68Å; P55-I185 WeakPolarHBondContact O-CG2 3.48Å; L181-I185 HydrophobicContact CD1-CD1 4.23Å; L181-I185 HydrophobicContact CD1-CG1 4.29Å; L181-I185 HydrophobicContact CD2-CD1 4.39Å; L181-I185 HydrophobicContact CG-CD1 3.92Å; L181-I185 HydrophobicContact CG-CG1 4.4Å; L181-I185 WeakPolarHBondContact O-CG1 3.23Å; L181-I185 PolarHBondContact O-N 2.96Å; K182-I185 PolarHBondContact O-N 2.87Å; A183-I185 VanDerWaalsContact C-N 3.32Å; A183-I185 PolarHBondContact O-N 3.08Å; I185-D188 WeakPolarHBondContact O-CB 3.44Å; I185-D188 PolarHBondContact O-N 2.99Å; I185-V189 WeakPolarHBondContact O-CG2 3.38Å; I185-V189 PolarHBondContact O-N 3.38Å; I185-V189 VanDerWaalsContact O-N 3.1Å
186	W	90.6	Very high	87.8	Confident	91 Å²	91	23.2 Å²	23.2	35%	0.345	11%	0.112	S	C	.	.	H	α-helix	trans	-72.9	-35.4	179.1	-80.3	108.8	0	0	0	113.1	I27 Y31 P55 K182 A183 V184 D188 V189 F190	I27-W186 HydrophobicContact CG2-CB 4.09Å; Y31-W186 HydrophobicContact CD2-CB 4.03Å; Y31-W186 HydrophobicContact CD2-CG 4.3Å; Y31-W186 AromaticContact CE1-CD1 3.83Å; Y31-W186 HydrophobicContact CE1-CG 4.49Å; Y31-W186 HydrophobicContact CE2-CB 3.64Å; Y31-W186 AromaticContact CE2-CD1 3.7Å; Y31-W186 HydrophobicContact CE2-CD2 4.27Å; Y31-W186 AromaticContact CE2-CG 3.59Å; Y31-W186 HydrophobicContact CE2-CG 3.59Å; Y31-W186 AromaticContact CZ-CD1 3.44Å; Y31-W186 VanDerWaalsContact CZ-CD1 3.44Å; Y31-W186 AromaticContact CZ-CG 3.7Å; Y31-W186 AromaticContact CZ-NE1 3.73Å; Y31-W186 PolarHBondContact OH-NE1 3.25Å; P55-W186 HydrophobicContact CG-CH2 4.22Å; P55-W186 HydrophobicContact CG-CZ2 4.29Å; K182-W186 PolarHBondContact O-N 2.9Å; A183-W186 PolarHBondContact O-N 3.41Å; A183-W186 VanDerWaalsContact O-N 3.12Å; V184-W186 PolarHBondContact O-N 3.34Å; W186-D188 VanDerWaalsContact C-N 3.29Å; W186-V189 PolarHBondContact O-N 2.79Å; W186-F190 PolarHBondContact O-N 3.41Å
187	T	91	Very high	88.7	Confident	0 Å²	0	25.3 Å²	25.3	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-63.3	-39.7	170.9	51	0	0	0	0	110.9	S24 I27 A183 V184 V189 F190 Q191	S24-T187 WeakPolarHBondContact O-CG2 3.21Å; I27-T187 HydrophobicContact CB-CG2 4.06Å; I27-T187 HydrophobicContact CG2-CG2 3.85Å; A183-T187 WeakPolarHBondContact O-CG2 3.37Å; A183-T187 PolarHBondContact O-N 2.74Å; A183-T187 PolarHBondContact O-OG1 2.71Å; A183-T187 VanDerWaalsContact O-OG1 3.1Å; V184-T187 VanDerWaalsContact CA-OG1 3.3Å; V184-T187 WeakPolarHBondContact CA-OG1 3.17Å; V184-T187 PolarHBondContact O-N 2.7Å; V184-T187 PolarHBondContact O-OG1 2.86Å; T187-V189 VanDerWaalsContact C-N 3.32Å; T187-V189 PolarHBondContact O-N 2.66Å; T187-F190 PolarHBondContact O-N 3.07Å; T187-Q191 WeakPolarHBondContact O-CB 3.14Å; T187-Q191 WeakPolarHBondContact O-CG 3.41Å; T187-Q191 PolarHBondContact O-N 2.85Å
188	D	92.6	Very high	89.7	Confident	0 Å²	0	24.7 Å²	24.7	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-64	-37	178.2	-70.9	-9.2	0	0	0	112.1	S59 A62 V184 I185 W186 Q191 T192 R265 S350	S59-D188 WeakPolarHBondContact CB-OD2 3.28Å; S59-D188 PolarHBondContact OG-OD2 2.76Å; A62-D188 HydrophobicContact CB-CB 3.67Å; V184-D188 WeakPolarHBondContact O-CB 3.41Å; V184-D188 PolarHBondContact O-N 3.44Å; I185-D188 WeakPolarHBondContact O-CB 3.44Å; I185-D188 PolarHBondContact O-N 2.99Å; W186-D188 VanDerWaalsContact C-N 3.29Å; D188-Q191 PolarHBondContact O-N 3.1Å; D188-T192 WeakPolarHBondContact O-CB 3.42Å; D188-T192 PolarHBondContact O-N 3.12Å; D188-T192 PolarHBondContact O-OG1 2.97Å; D188-R265 IonicContact OD2-CZ 2.64Å; D188-R265 IonicContact OD2-NE 2.62Å; D188-R265 IonicContact OD2-NH2 3.47Å; D188-R265 PolarHBondContact OD2-NH2 3.06Å; D188-S350 WeakPolarHBondContact OD1-CA 3.5Å; D188-S350 VanDerWaalsContact OD1-CB 3.23Å; D188-S350 WeakPolarHBondContact OD1-CB 3.32Å
189	V	93.4	Very high	90.7	Very high	23 Å²	23	21.3 Å²	21.3	14%	0.139	11%	0.108	C	C	.	.	H	α-helix	trans	-58.9	-50.5	175.6	167.6	0	0	0	0	110.4	P55 L58 I185 W186 T187 L193	P55-V189 HydrophobicContact CB-CG2 4.11Å; L58-V189 HydrophobicContact CB-CG2 4Å; L58-V189 HydrophobicContact CD1-CB 4.4Å; L58-V189 HydrophobicContact CD1-CG1 3.91Å; L58-V189 HydrophobicContact CD1-CG2 4.08Å; I185-V189 WeakPolarHBondContact O-CG2 3.38Å; I185-V189 PolarHBondContact O-N 3.38Å; I185-V189 VanDerWaalsContact O-N 3.1Å; W186-V189 PolarHBondContact O-N 2.79Å; T187-V189 VanDerWaalsContact C-N 3.32Å; T187-V189 PolarHBondContact O-N 2.66Å; V189-L193 PolarHBondContact O-N 3.05Å
190	F	93.3	Very high	91.7	Very high	52 Å²	52	24.5 Å²	24.5	23%	0.228	12%	0.124	C	C	.	.	H	α-helix	trans	-62.6	-47.7	177.3	173.3	-102.6	0	0	0	111.4	L20 A23 I27 W186 T187 T192 L193 V194	L20-F190 HydrophobicContact CD2-CZ 3.9Å; A23-F190 HydrophobicContact CB-CE1 3.9Å; A23-F190 HydrophobicContact CB-CE2 4.47Å; A23-F190 HydrophobicContact CB-CZ 3.7Å; I27-F190 HydrophobicContact CD1-CB 3.61Å; I27-F190 HydrophobicContact CD1-CD1 4.07Å; I27-F190 HydrophobicContact CD1-CD2 4.13Å; I27-F190 HydrophobicContact CD1-CG 3.66Å; W186-F190 PolarHBondContact O-N 3.41Å; T187-F190 PolarHBondContact O-N 3.07Å; F190-T192 VanDerWaalsContact C-N 3.32Å; F190-T192 PolarHBondContact O-N 3.19Å; F190-L193 WeakPolarHBondContact O-CB 3.34Å; F190-L193 PolarHBondContact O-N 3.32Å; F190-L193 VanDerWaalsContact O-N 3.11Å; F190-V194 HydrophobicContact CD1-CG2 4.29Å; F190-V194 HydrophobicContact CE1-CG2 3.82Å; F190-V194 HydrophobicContact CE2-CG2 4.25Å; F190-V194 HydrophobicContact CZ-CG2 3.8Å; F190-V194 PolarHBondContact O-N 2.83Å
191	Q	93.8	Very high	92.3	Very high	0 Å²	0	25.3 Å²	25.3	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-60.9	-38.9	-178.7	-74.7	171.2	-19.7	0	0	112.2	T187 D188 L193 V194 M195 S350	T187-Q191 WeakPolarHBondContact O-CB 3.14Å; T187-Q191 WeakPolarHBondContact O-CG 3.41Å; T187-Q191 PolarHBondContact O-N 2.85Å; D188-Q191 PolarHBondContact O-N 3.1Å; Q191-L193 VanDerWaalsContact C-N 3.3Å; Q191-L193 PolarHBondContact O-N 3.07Å; Q191-V194 PolarHBondContact O-N 2.64Å; Q191-M195 WeakPolarHBondContact O-CG 3.31Å; Q191-M195 PolarHBondContact O-N 3.36Å; Q191-M195 VanDerWaalsContact O-SD 3.37Å; Q191-S350 VanDerWaalsContact OE1-CB 3.29Å
192	T	93.4	Very high	92.8	Very high	1 Å²	1	25.3 Å²	25.3	1%	0.006	13%	0.13	C	C	.	.	H	α-helix	trans	-58.6	-41.5	175.5	-58	0	0	0	0	111.8	L58 I61 A62 D188 F190 M195 F196	L58-T192 HydrophobicContact CD2-CG2 4.02Å; L58-T192 PolarHBondContact O-OG1 3.45Å; I61-T192 HydrophobicContact CG2-CG2 4.49Å; A62-T192 WeakPolarHBondContact CB-OG1 3.47Å; D188-T192 WeakPolarHBondContact O-CB 3.42Å; D188-T192 PolarHBondContact O-N 3.12Å; D188-T192 PolarHBondContact O-OG1 2.97Å; F190-T192 VanDerWaalsContact C-N 3.32Å; F190-T192 PolarHBondContact O-N 3.19Å; T192-M195 WeakPolarHBondContact O-CB 3.49Å; T192-M195 PolarHBondContact O-N 3.18Å; T192-F196 HydrophobicContact CG2-CD2 3.79Å; T192-F196 HydrophobicContact CG2-CE2 3.54Å; T192-F196 WeakPolarHBondContact O-CD2 3.36Å; T192-F196 PolarHBondContact O-N 3.47Å; T192-F196 VanDerWaalsContact O-N 3.12Å
193	L	93.8	Very high	93.3	Very high	108 Å²	108	22.6 Å²	22.6	57%	0.565	12%	0.119	S	C	*	.	H	α-helix	trans	-64.9	-43.8	177.5	-62.3	173.9	0	0	0	111.3	V189 F190 Q191 M195 F196 A197	V189-L193 PolarHBondContact O-N 3.05Å; F190-L193 WeakPolarHBondContact O-CB 3.34Å; F190-L193 PolarHBondContact O-N 3.32Å; F190-L193 VanDerWaalsContact O-N 3.11Å; Q191-L193 VanDerWaalsContact C-N 3.3Å; Q191-L193 PolarHBondContact O-N 3.07Å; L193-M195 VanDerWaalsContact C-N 3.28Å; L193-M195 PolarHBondContact O-N 3.09Å; L193-F196 PolarHBondContact O-N 3.12Å; L193-A197 WeakPolarHBondContact O-CB 3.44Å; L193-A197 PolarHBondContact O-N 2.81Å
194	V	94.9	Very high	93.7	Very high	10 Å²	10	27.5 Å²	27.5	6%	0.061	14%	0.144	C	C	.	.	H	α-helix	trans	-61.3	-39.7	176	-179.1	0	0	0	0	110.8	L20 F190 Q191 A197 G198 L339 A342 C343	L20-V194 HydrophobicContact CD1-CG1 4.13Å; L20-V194 HydrophobicContact CD2-CG2 4.08Å; F190-V194 HydrophobicContact CD1-CG2 4.29Å; F190-V194 HydrophobicContact CE1-CG2 3.82Å; F190-V194 HydrophobicContact CE2-CG2 4.25Å; F190-V194 HydrophobicContact CZ-CG2 3.8Å; F190-V194 PolarHBondContact O-N 2.83Å; Q191-V194 PolarHBondContact O-N 2.64Å; V194-A197 PolarHBondContact O-N 3.34Å; V194-G198 PolarHBondContact O-N 3.47Å; V194-L339 HydrophobicContact CG1-CD1 4.43Å; V194-A342 HydrophobicContact CG1-CB 4.32Å; V194-C343 HydrophobicContact CG1-CB 4.49Å
195	M	93.8	Very high	94.1	Very high	4 Å²	4	28.1 Å²	28.1	2%	0.02	15%	0.148	C	C	.	.	H	α-helix	trans	-61.6	-50.8	179.3	-68.7	156.9	61.6	0	0	112	Q65 I70 Q191 T192 L193 G198 Q199 C343 A347	Q65-M195 HydrophobicContact CB-CE 3.57Å; Q65-M195 HydrophobicContact CG-CE 3.26Å; Q65-M195 WeakPolarHBondContact O-CE 3.09Å; I70-M195 HydrophobicContact CD1-CB 4.41Å; I70-M195 HydrophobicContact CD1-CE 4.29Å; I70-M195 HydrophobicContact CD1-CG 4.34Å; Q191-M195 WeakPolarHBondContact O-CG 3.31Å; Q191-M195 PolarHBondContact O-N 3.36Å; Q191-M195 VanDerWaalsContact O-SD 3.37Å; T192-M195 WeakPolarHBondContact O-CB 3.49Å; T192-M195 PolarHBondContact O-N 3.18Å; L193-M195 VanDerWaalsContact C-N 3.28Å; L193-M195 PolarHBondContact O-N 3.09Å; M195-G198 PolarHBondContact O-N 3.44Å; M195-Q199 WeakPolarHBondContact O-CG 3.46Å; M195-Q199 PolarHBondContact O-N 2.83Å; M195-Q199 VanDerWaalsContact O-N 3.13Å; M195-C343 VanDerWaalsContact CA-SG 3.57Å; M195-C343 PolarHBondContact O-SG 3.28Å; M195-A347 HydrophobicContact CE-CB 3.72Å; M195-A347 HydrophobicContact CG-CB 3.96Å; M195-A347 HydrophobicContact SD-CB 3.91Å
196	F	94.1	Very high	94.2	Very high	32 Å²	32	28.1 Å²	28.1	14%	0.14	15%	0.148	C	C	.	.	H	α-helix	trans	-64	-43.1	176.8	-76.8	-65.6	0	0	0	112	T192 L193 G198 Q199 I200 L288 A289 L292	T192-F196 HydrophobicContact CG2-CD2 3.79Å; T192-F196 HydrophobicContact CG2-CE2 3.54Å; T192-F196 WeakPolarHBondContact O-CD2 3.36Å; T192-F196 PolarHBondContact O-N 3.47Å; T192-F196 VanDerWaalsContact O-N 3.12Å; L193-F196 PolarHBondContact O-N 3.12Å; F196-G198 PolarHBondContact O-N 3.42Å; F196-Q199 PolarHBondContact O-N 3.17Å; F196-I200 WeakPolarHBondContact O-CB 3.12Å; F196-I200 WeakPolarHBondContact O-CD1 3.41Å; F196-I200 VanDerWaalsContact O-CG1 3.22Å; F196-I200 WeakPolarHBondContact O-CG1 3.36Å; F196-I200 PolarHBondContact O-N 2.91Å; F196-L288 HydrophobicContact CD1-CD2 4.32Å; F196-L288 HydrophobicContact CE1-CB 4.47Å; F196-L288 HydrophobicContact CE1-CD2 3.94Å; F196-L288 HydrophobicContact CE1-CG 3.99Å; F196-L288 HydrophobicContact CZ-CD2 4.43Å; F196-A289 HydrophobicContact CE1-CB 4.11Å; F196-A289 HydrophobicContact CZ-CB 4.33Å; F196-L292 HydrophobicContact CD1-CD1 3.66Å; F196-L292 HydrophobicContact CE1-CD1 4.11Å
197	A	95.4	Very high	94.5	Very high	46 Å²	46	24.6 Å²	24.6	38%	0.38	14%	0.136	S	C	.	.	H	α-helix	trans	-59.4	-45.4	178.1	0	0	0	0	0	112	L193 V194 I200 A201	L193-A197 WeakPolarHBondContact O-CB 3.44Å; L193-A197 PolarHBondContact O-N 2.81Å; V194-A197 PolarHBondContact O-N 3.34Å; A197-I200 PolarHBondContact O-N 3.43Å; A197-A201 WeakPolarHBondContact O-CB 3.37Å; A197-A201 PolarHBondContact O-N 3.26Å
198	G	94.7	Very high	94.7	Very high	1 Å²	1	31.4 Å²	31.4	1%	0.01	17%	0.168	C	C	.	.	H	α-helix	trans	-63.8	-43.2	178.2	0	0	0	0	0	113.2	V194 M195 F196 V202	V194-G198 PolarHBondContact O-N 3.47Å; M195-G198 PolarHBondContact O-N 3.44Å; F196-G198 PolarHBondContact O-N 3.42Å; G198-V202 WeakPolarHBondContact O-CG2 3.41Å; G198-V202 PolarHBondContact O-N 3.32Å
199	Q	94.2	Very high	94.6	Very high	1 Å²	1	37.4 Å²	37.4	1%	0.005	19%	0.191	C	C	.	.	H	α-helix	trans	-65.4	-45.4	176.8	-71.8	-173	-47.7	0	0	112	I70 M195 F196 A201 V202 I203 S293	I70-Q199 HydrophobicContact CG2-CG 4.2Å; M195-Q199 WeakPolarHBondContact O-CG 3.46Å; M195-Q199 PolarHBondContact O-N 2.83Å; M195-Q199 VanDerWaalsContact O-N 3.13Å; F196-Q199 PolarHBondContact O-N 3.17Å; Q199-A201 PolarHBondContact O-N 2.79Å; Q199-V202 PolarHBondContact O-N 3.15Å; Q199-I203 WeakPolarHBondContact O-CD1 3.46Å; Q199-I203 VanDerWaalsContact O-CG1 3.26Å; Q199-I203 WeakPolarHBondContact O-CG1 3.35Å; Q199-I203 PolarHBondContact O-N 3.04Å; Q199-S293 PolarHBondContact NE2-OG 3.42Å
200	I	96.1	Very high	94.5	Very high	70 Å²	70	36.9 Å²	36.9	36%	0.359	19%	0.188	S	C	.	.	H	α-helix	trans	-62.3	-43.8	179.5	-70.2	167.3	0	0	0	110.6	F196 A197 V202 I203 I204 L292	F196-I200 WeakPolarHBondContact O-CB 3.12Å; F196-I200 WeakPolarHBondContact O-CD1 3.41Å; F196-I200 VanDerWaalsContact O-CG1 3.22Å; F196-I200 WeakPolarHBondContact O-CG1 3.36Å; F196-I200 PolarHBondContact O-N 2.91Å; A197-I200 PolarHBondContact O-N 3.43Å; I200-V202 PolarHBondContact O-N 3.09Å; I200-I203 PolarHBondContact O-N 3.06Å; I200-I204 HydrophobicContact CG2-CD1 3.54Å; I200-I204 HydrophobicContact CG2-CG1 4.18Å; I200-I204 WeakPolarHBondContact O-CG1 3.41Å; I200-I204 PolarHBondContact O-N 3.09Å; I200-L292 HydrophobicContact CD1-CD1 4.48Å; I200-L292 HydrophobicContact CG1-CD1 4.03Å; I200-L292 HydrophobicContact CG1-CD2 4.02Å
201	A	95.6	Very high	94.4	Very high	19 Å²	19	37 Å²	37	16%	0.157	20%	0.203	C	C	.	.	H	α-helix	trans	-58.4	-46.9	178.6	0	0	0	0	0	112.2	A197 Q199 I203 I204 V205 L336 L339	A197-A201 WeakPolarHBondContact O-CB 3.37Å; A197-A201 PolarHBondContact O-N 3.26Å; Q199-A201 PolarHBondContact O-N 2.79Å; A201-I203 VanDerWaalsContact C-N 3.34Å; A201-I203 PolarHBondContact O-N 3.21Å; A201-I204 PolarHBondContact O-N 3.46Å; A201-V205 WeakPolarHBondContact O-CG2 3.23Å; A201-V205 PolarHBondContact O-N 3.26Å; A201-V205 VanDerWaalsContact O-N 3.13Å; A201-L336 HydrophobicContact CB-CD2 4.34Å; A201-L339 HydrophobicContact CB-CD2 4.18Å
202	V	95.4	Very high	94.4	Very high	0 Å²	0	38 Å²	38	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-61.3	-43	176.6	170.7	0	0	0	0	111.6	G198 Q199 I200 G206 M296 F325 V326 L330 F340	G198-V202 WeakPolarHBondContact O-CG2 3.41Å; G198-V202 PolarHBondContact O-N 3.32Å; Q199-V202 PolarHBondContact O-N 3.15Å; I200-V202 PolarHBondContact O-N 3.09Å; V202-G206 WeakPolarHBondContact O-CA 3.3Å; V202-G206 PolarHBondContact O-N 3.31Å; V202-M296 HydrophobicContact CB-SD 4.19Å; V202-M296 HydrophobicContact CG1-CG 4.31Å; V202-M296 HydrophobicContact CG1-SD 3.59Å; V202-M296 VanDerWaalsContact CG1-SD 3.59Å; V202-F325 HydrophobicContact CG1-CD1 4.23Å; V202-F325 HydrophobicContact CG1-CE1 3.65Å; V202-V326 HydrophobicContact CG1-CG2 3.83Å; V202-V326 HydrophobicContact CG2-CG1 3.96Å; V202-V326 HydrophobicContact CG2-CG2 3.98Å; V202-L330 HydrophobicContact CG2-CD1 4Å; V202-F340 HydrophobicContact CG2-CB 4.25Å; V202-F340 HydrophobicContact CG2-CD2 3.56Å; V202-F340 HydrophobicContact CG2-CE2 4.19Å; V202-F340 HydrophobicContact CG2-CG 4.11Å
203	I	96.3	Very high	94.3	Very high	16 Å²	16	43 Å²	43	8%	0.082	24%	0.239	C	C	.	.	H	α-helix	trans	-65.2	-47	-178.9	-69.4	162	0	0	0	110.9	Q199 I200 A201 G206 V207 L292 I295 M296	Q199-I203 WeakPolarHBondContact O-CD1 3.46Å; Q199-I203 VanDerWaalsContact O-CG1 3.26Å; Q199-I203 WeakPolarHBondContact O-CG1 3.35Å; Q199-I203 PolarHBondContact O-N 3.04Å; I200-I203 PolarHBondContact O-N 3.06Å; A201-I203 VanDerWaalsContact C-N 3.34Å; A201-I203 PolarHBondContact O-N 3.21Å; I203-G206 PolarHBondContact O-N 2.78Å; I203-V207 HydrophobicContact CG2-CG2 4.36Å; I203-V207 WeakPolarHBondContact O-CB 3.39Å; I203-V207 VanDerWaalsContact O-CG2 3.25Å; I203-V207 WeakPolarHBondContact O-CG2 3.12Å; I203-V207 PolarHBondContact O-N 2.86Å; I203-L292 HydrophobicContact CD1-CB 3.8Å; I203-L292 HydrophobicContact CD1-CD2 3.75Å; I203-L292 HydrophobicContact CD1-CG 4.37Å; I203-L292 VanDerWaalsContact CD1-O 3.24Å; I203-L292 WeakPolarHBondContact CD1-O 3.41Å; I203-I295 HydrophobicContact CG2-CG2 3.62Å; I203-M296 HydrophobicContact CD1-CB 4.32Å; I203-M296 HydrophobicContact CG1-CB 3.94Å; I203-M296 HydrophobicContact CG1-CG 4.41Å
204	I	96.3	Very high	94.3	Very high	104 Å²	104	42.5 Å²	42.5	53%	0.533	24%	0.244	S	C	.	.	H	α-helix	trans	-59.5	-53.3	-179.2	-69.3	171	0	0	0	110.1	I200 A201 G206 V207 E208	I200-I204 HydrophobicContact CG2-CD1 3.54Å; I200-I204 HydrophobicContact CG2-CG1 4.18Å; I200-I204 WeakPolarHBondContact O-CG1 3.41Å; I200-I204 PolarHBondContact O-N 3.09Å; A201-I204 PolarHBondContact O-N 3.46Å; I204-G206 VanDerWaalsContact C-N 3.33Å; I204-G206 PolarHBondContact O-N 2.86Å; I204-V207 PolarHBondContact O-N 3.48Å; I204-E208 PolarHBondContact O-N 3.01Å; I204-E208 VanDerWaalsContact O-N 3.09Å
205	V	95.9	Very high	94.2	Very high	12 Å²	12	44.4 Å²	44.4	7%	0.073	25%	0.252	C	S	.	.	H	α-helix	trans	-64.7	-40.4	-179.5	177.9	0	0	0	0	111	A201 V207 E208 R209 M329 L330 L333 L336	A201-V205 WeakPolarHBondContact O-CG2 3.23Å; A201-V205 PolarHBondContact O-N 3.26Å; A201-V205 VanDerWaalsContact O-N 3.13Å; V205-V207 PolarHBondContact O-N 3.2Å; V205-E208 PolarHBondContact O-N 2.98Å; V205-R209 HydrophobicContact CG1-CG 3.96Å; V205-R209 WeakPolarHBondContact O-CB 3.38Å; V205-R209 WeakPolarHBondContact O-CG 3.47Å; V205-R209 PolarHBondContact O-N 3Å; V205-M329 HydrophobicContact CG1-CB 4.44Å; V205-M329 WeakPolarHBondContact CG1-O 3.48Å; V205-L330 HydrophobicContact CB-CD2 3.9Å; V205-L330 HydrophobicContact CG1-CD2 3.98Å; V205-L330 HydrophobicContact CG2-CD2 4.01Å; V205-L333 HydrophobicContact CB-CD1 4.49Å; V205-L333 HydrophobicContact CG1-CD1 3.72Å; V205-L333 HydrophobicContact CG2-CD1 3.87Å; V205-L336 HydrophobicContact CG2-CD1 3.94Å
206	G	94.6	Very high	94.1	Very high	0 Å²	0	44.6 Å²	44.6	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-62	-42.2	178.3	0	0	0	0	0	112.7	V202 I203 I204 T210 V299	V202-G206 WeakPolarHBondContact O-CA 3.3Å; V202-G206 PolarHBondContact O-N 3.31Å; I203-G206 PolarHBondContact O-N 2.78Å; I204-G206 VanDerWaalsContact C-N 3.33Å; I204-G206 PolarHBondContact O-N 2.86Å; G206-T210 VanDerWaalsContact O-CB 3.27Å; G206-T210 WeakPolarHBondContact O-CB 3.24Å; G206-T210 PolarHBondContact O-N 3.35Å; G206-T210 VanDerWaalsContact O-N 3.1Å; G206-T210 PolarHBondContact O-OG1 3.46Å; G206-V299 VanDerWaalsContact C-CG1 3.46Å
207	V	95.9	Very high	94.1	Very high	17 Å²	17	49.8 Å²	49.8	10%	0.103	27%	0.272	C	S	.	.	H	α-helix	trans	-63.7	-46.1	175.8	169.8	0	0	0	0	110.7	I203 I204 V205 T210 G212 M213 V299	I203-V207 HydrophobicContact CG2-CG2 4.36Å; I203-V207 WeakPolarHBondContact O-CB 3.39Å; I203-V207 VanDerWaalsContact O-CG2 3.25Å; I203-V207 WeakPolarHBondContact O-CG2 3.12Å; I203-V207 PolarHBondContact O-N 2.86Å; I204-V207 PolarHBondContact O-N 3.48Å; V205-V207 PolarHBondContact O-N 3.2Å; V207-T210 PolarHBondContact O-N 3.3Å; V207-G212 VanDerWaalsContact O-CA 3.31Å; V207-G212 WeakPolarHBondContact O-CA 3.39Å; V207-G212 PolarHBondContact O-N 3.34Å; V207-M213 HydrophobicContact CG1-CB 4.01Å; V207-M213 HydrophobicContact CG1-CE 4.29Å; V207-M213 HydrophobicContact CG2-CE 4.01Å; V207-V299 HydrophobicContact CG2-CG1 4.49Å; V207-V299 HydrophobicContact CG2-CG2 3.59Å
208	E	94.4	Very high	93.9	Very high	143 Å²	143	52.4 Å²	52.4	67%	0.668	27%	0.272	S	S	*	.	H	α-helix	trans	-61	-50.8	179.6	-172.8	-179.5	178.8	0	0	111.7	I204 V205 T210 G211	I204-E208 PolarHBondContact O-N 3.01Å; I204-E208 VanDerWaalsContact O-N 3.09Å; V205-E208 PolarHBondContact O-N 2.98Å; E208-T210 PolarHBondContact O-N 3.43Å; E208-G211 PolarHBondContact O-N 3.17Å; E208-G211 VanDerWaalsContact O-N 3.12Å
209	R	92.3	Very high	93.6	Very high	127 Å²	127	54.4 Å²	54.4	48%	0.479	28%	0.281	S	S	.	.	H	α-helix	trans	-65.7	-21.8	-179.9	-67.5	-77.5	-172.4	137.2	10.5	113.7	V205 G211 M329 Q331	V205-R209 HydrophobicContact CG1-CG 3.96Å; V205-R209 WeakPolarHBondContact O-CB 3.38Å; V205-R209 WeakPolarHBondContact O-CG 3.47Å; V205-R209 PolarHBondContact O-N 3Å; R209-G211 VanDerWaalsContact C-N 3.32Å; R209-M329 HydrophobicContact CB-SD 3.69Å; R209-M329 HydrophobicContact CG-SD 4.37Å; R209-Q331 PolarHBondContact NH2-O 3.26Å
210	T	90.5	Very high	93.4	Very high	11 Å²	11	54.4 Å²	54.4	7%	0.067	28%	0.281	C	S	.	.	T	Hydrogen-bonded Turn	trans	-87.5	-0.8	178.4	-53.9	0	0	0	0	112.8	G206 V207 E208 V216 A302 R303	G206-T210 VanDerWaalsContact O-CB 3.27Å; G206-T210 WeakPolarHBondContact O-CB 3.24Å; G206-T210 PolarHBondContact O-N 3.35Å; G206-T210 VanDerWaalsContact O-N 3.1Å; G206-T210 PolarHBondContact O-OG1 3.46Å; V207-T210 PolarHBondContact O-N 3.3Å; E208-T210 PolarHBondContact O-N 3.43Å; T210-V216 HydrophobicContact CG2-CG2 3.74Å; T210-A302 HydrophobicContact CG2-CB 3.87Å; T210-R303 HydrophobicContact CG2-CB 4.28Å
211	G	90.5	Very high	93	Very high	54 Å²	54	58.1 Å²	58.1	56%	0.557	29%	0.294	S	S	*	.	T	Hydrogen-bonded Turn	trans	100.8	16.4	-179.8	0	0	0	0	0	114.3	E208 R209	E208-G211 PolarHBondContact O-N 3.17Å; E208-G211 VanDerWaalsContact O-N 3.12Å; R209-G211 VanDerWaalsContact C-N 3.32Å
212	G	93.5	Very high	92.6	Very high	22 Å²	22	60.6 Å²	60.6	23%	0.227	30%	0.302	C	S	.	.			trans	92.5	170.1	177.7	0	0	0	0	0	114.4	V207 S214 E215 V216	V207-G212 VanDerWaalsContact O-CA 3.31Å; V207-G212 WeakPolarHBondContact O-CA 3.39Å; V207-G212 PolarHBondContact O-N 3.34Å; G212-S214 VanDerWaalsContact C-N 3.31Å; G212-S214 PolarHBondContact O-N 2.77Å; G212-E215 PolarHBondContact O-N 3.12Å; G212-V216 WeakPolarHBondContact O-CG2 3.36Å; G212-V216 PolarHBondContact O-N 2.82Å; G212-V216 VanDerWaalsContact O-N 3.11Å
213	M	92.7	Very high	91.9	Very high	107 Å²	107	60.6 Å²	60.6	53%	0.527	30%	0.302	S	S	.	.	H	α-helix	trans	-64.1	-35.3	-174	-174.9	62.4	76.6	0	0	112.7	V207 V216 W217	V207-M213 HydrophobicContact CG1-CB 4.01Å; V207-M213 HydrophobicContact CG1-CE 4.29Å; V207-M213 HydrophobicContact CG2-CE 4.01Å; M213-V216 PolarHBondContact O-N 3.31Å; M213-W217 WeakPolarHBondContact O-CB 3.26Å; M213-W217 PolarHBondContact O-N 3.29Å
214	S	93.2	Very high	91.3	Very high	96 Å²	96	64.4 Å²	64.4	67%	0.671	32%	0.323	S	S	*	.	H	α-helix	trans	-62	-44.4	177.9	49.2	0	0	0	0	111.7	G212 W217 R218	G212-S214 VanDerWaalsContact C-N 3.31Å; G212-S214 PolarHBondContact O-N 2.77Å; S214-W217 PolarHBondContact O-N 3.43Å; S214-R218 WeakPolarHBondContact O-CB 3.45Å; S214-R218 PolarHBondContact O-N 2.96Å
215	E	92.1	Very high	90.8	Very high	51 Å²	51	59.8 Å²	59.8	24%	0.238	30%	0.299	C	S	.	.	H	α-helix	trans	-70.3	-41.1	179.9	-178.1	57.6	-166	0	0	111.7	G212 W217 R218 K219	G212-E215 PolarHBondContact O-N 3.12Å; E215-W217 VanDerWaalsContact C-N 3.32Å; E215-W217 PolarHBondContact O-N 3.4Å; E215-R218 PolarHBondContact O-N 3.47Å; E215-R218 IonicContact OE1-CZ 3.98Å; E215-R218 IonicContact OE1-NE 2.79Å; E215-R218 IonicContact OE1-NH2 3.59Å; E215-R218 PolarHBondContact OE1-NH2 2.69Å; E215-R218 IonicContact OE2-CZ 2.83Å; E215-R218 IonicContact OE2-NE 2.72Å; E215-R218 PolarHBondContact OE2-NE 3.36Å; E215-R218 IonicContact OE2-NH2 3.02Å; E215-R218 PolarHBondContact OE2-NH2 3.06Å; E215-K219 WeakPolarHBondContact O-CG 3.27Å; E215-K219 PolarHBondContact O-N 3.45Å; E215-K219 WeakPolarHBondContact OE1-CE 3.23Å
216	V	93.2	Very high	90.3	Very high	7 Å²	7	62 Å²	62	4%	0.042	31%	0.31	C	S	.	.	H	α-helix	trans	-55.9	-49.5	171.9	171.5	0	0	0	0	110.3	T210 G212 M213 R218 K219 V220 V299 A302	T210-V216 HydrophobicContact CG2-CG2 3.74Å; G212-V216 WeakPolarHBondContact O-CG2 3.36Å; G212-V216 PolarHBondContact O-N 2.82Å; G212-V216 VanDerWaalsContact O-N 3.11Å; M213-V216 PolarHBondContact O-N 3.31Å; V216-R218 VanDerWaalsContact C-N 3.35Å; V216-R218 PolarHBondContact O-N 3.04Å; V216-K219 PolarHBondContact O-N 3.32Å; V216-V220 HydrophobicContact CG1-CG2 4.31Å; V216-V220 VanDerWaalsContact O-CB 3.3Å; V216-V220 WeakPolarHBondContact O-CB 3.47Å; V216-V220 WeakPolarHBondContact O-CG2 3.48Å; V216-V220 PolarHBondContact O-N 3.27Å; V216-V299 HydrophobicContact CG1-CG2 4.07Å; V216-A302 HydrophobicContact CB-CB 4.16Å; V216-A302 HydrophobicContact CG1-CB 3.92Å; V216-A302 HydrophobicContact CG2-CB 4.11Å
217	W	92.4	Very high	89.5	Confident	141 Å²	141	63.4 Å²	63.4	53%	0.534	32%	0.32	S	S	.	.	H	α-helix	trans	-63.3	-40.4	-179.7	-168.9	-105.4	0	0	0	112.6	M213 S214 E215 V220 K221 L226	M213-W217 WeakPolarHBondContact O-CB 3.26Å; M213-W217 PolarHBondContact O-N 3.29Å; S214-W217 PolarHBondContact O-N 3.43Å; E215-W217 VanDerWaalsContact C-N 3.32Å; E215-W217 PolarHBondContact O-N 3.4Å; W217-V220 PolarHBondContact O-N 3.2Å; W217-K221 WeakPolarHBondContact O-CB 3.4Å; W217-K221 PolarHBondContact O-N 3.45Å; W217-L226 HydrophobicContact CH2-CD1 3.75Å; W217-L226 HydrophobicContact CH2-CD2 4.29Å; W217-L226 HydrophobicContact CZ2-CD1 3.84Å; W217-L226 HydrophobicContact CZ3-CD1 4.3Å; W217-L226 HydrophobicContact CZ3-CD2 4.32Å
218	R	91.8	Very high	88.8	Confident	102 Å²	102	65.4 Å²	65.4	39%	0.385	34%	0.344	S	S	.	.	H	α-helix	trans	-59.5	-53.7	176.4	-170.3	-172.2	70.8	76.5	2.7	111.2	S214 E215 V216 V220 K221 E222	S214-R218 WeakPolarHBondContact O-CB 3.45Å; S214-R218 PolarHBondContact O-N 2.96Å; E215-R218 PolarHBondContact O-N 3.47Å; E215-R218 IonicContact OE1-CZ 3.98Å; E215-R218 IonicContact OE1-NE 2.79Å; E215-R218 IonicContact OE1-NH2 3.59Å; E215-R218 PolarHBondContact OE1-NH2 2.69Å; E215-R218 IonicContact OE2-CZ 2.83Å; E215-R218 IonicContact OE2-NE 2.72Å; E215-R218 PolarHBondContact OE2-NE 3.36Å; E215-R218 IonicContact OE2-NH2 3.02Å; E215-R218 PolarHBondContact OE2-NH2 3.06Å; V216-R218 VanDerWaalsContact C-N 3.35Å; V216-R218 PolarHBondContact O-N 3.04Å; R218-V220 PolarHBondContact O-N 3.42Å; R218-K221 PolarHBondContact O-N 3.16Å; R218-E222 WeakPolarHBondContact CG-OE1 3.47Å; R218-E222 IonicContact CZ-OE1 3.95Å; R218-E222 IonicContact CZ-OE2 3.53Å; R218-E222 IonicContact NH1-OE1 3.81Å; R218-E222 PolarHBondContact NH1-OE1 2.77Å; R218-E222 IonicContact NH1-OE2 2.68Å; R218-E222 PolarHBondContact NH1-OE2 3.29Å; R218-E222 WeakPolarHBondContact O-CG 3.4Å; R218-E222 PolarHBondContact O-N 3.44Å
219	K	89.2	Confident	88.2	Confident	43 Å²	43	63.1 Å²	63.1	19%	0.187	34%	0.336	C	S	.	.	H	α-helix	trans	-62.3	-40.3	179.4	-68.9	-175.3	-177	-173.2	0	112.7	E215 V216 K221 E222 G223 A302	E215-K219 WeakPolarHBondContact O-CG 3.27Å; E215-K219 PolarHBondContact O-N 3.45Å; E215-K219 WeakPolarHBondContact OE1-CE 3.23Å; V216-K219 PolarHBondContact O-N 3.32Å; K219-K221 VanDerWaalsContact C-N 3.34Å; K219-E222 PolarHBondContact O-N 3.05Å; K219-G223 PolarHBondContact O-N 3.49Å; K219-A302 HydrophobicContact CB-CB 4.09Å; K219-A302 HydrophobicContact CD-CB 4.16Å; K219-A302 WeakPolarHBondContact CD-O 3.39Å; K219-A302 PolarHBondContact NZ-O 3.18Å
220	V	89.9	Confident	87.8	Confident	1 Å²	1	59.9 Å²	59.9	1%	0.006	33%	0.328	C	S	.	.	H	α-helix	trans	-63.6	-40.5	177.6	161.7	0	0	0	0	111.7	V216 W217 R218 N224 R225 L226 L298 F301 A302	V216-V220 HydrophobicContact CG1-CG2 4.31Å; V216-V220 VanDerWaalsContact O-CB 3.3Å; V216-V220 WeakPolarHBondContact O-CB 3.47Å; V216-V220 WeakPolarHBondContact O-CG2 3.48Å; V216-V220 PolarHBondContact O-N 3.27Å; W217-V220 PolarHBondContact O-N 3.2Å; R218-V220 PolarHBondContact O-N 3.42Å; V220-N224 PolarHBondContact O-N 2.93Å; V220-R225 HydrophobicContact CG1-CB 4.31Å; V220-R225 PolarHBondContact O-N 3.29Å; V220-L226 HydrophobicContact CG1-CD1 4.25Å; V220-L226 HydrophobicContact CG1-CD2 3.69Å; V220-L226 HydrophobicContact CG1-CG 3.65Å; V220-L298 HydrophobicContact CG1-CD1 4.46Å; V220-L298 HydrophobicContact CG1-CD2 3.78Å; V220-L298 HydrophobicContact CG2-CB 4.06Å; V220-L298 HydrophobicContact CG2-CD2 4.02Å; V220-F301 HydrophobicContact CG2-CD1 4.17Å; V220-A302 HydrophobicContact CG2-CB 4.39Å
221	K	87.9	Confident	87.7	Confident	148 Å²	148	63.8 Å²	63.8	64%	0.643	35%	0.348	S	S	*	.	H	α-helix	trans	-68.7	-44.5	177.5	-170.9	178.5	-178.8	-176.5	0	111.7	W217 R218 K219 N224	W217-K221 WeakPolarHBondContact O-CB 3.4Å; W217-K221 PolarHBondContact O-N 3.45Å; R218-K221 PolarHBondContact O-N 3.16Å; K219-K221 VanDerWaalsContact C-N 3.34Å; K221-N224 PolarHBondContact O-N 3.04Å
222	E	86.7	Confident	87.5	Confident	70 Å²	70	63.9 Å²	63.9	33%	0.327	34%	0.336	S	S	.	.	H	α-helix	trans	-68.5	-34.8	178.7	-70.7	171.1	-174.8	0	0	112.9	R218 K219 N224 C475 H476	R218-E222 WeakPolarHBondContact CG-OE1 3.47Å; R218-E222 IonicContact CZ-OE1 3.95Å; R218-E222 IonicContact CZ-OE2 3.53Å; R218-E222 IonicContact NH1-OE1 3.81Å; R218-E222 PolarHBondContact NH1-OE1 2.77Å; R218-E222 IonicContact NH1-OE2 2.68Å; R218-E222 PolarHBondContact NH1-OE2 3.29Å; R218-E222 WeakPolarHBondContact O-CG 3.4Å; R218-E222 PolarHBondContact O-N 3.44Å; K219-E222 PolarHBondContact O-N 3.05Å; E222-N224 PolarHBondContact O-N 2.93Å; E222-C475 CarbonylContact C-O 3.37Å; E222-C475 VanDerWaalsContact C-O 3.28Å; E222-C475 WeakPolarHBondContact CB-O 3.23Å; E222-H476 IonicContact OE2-CE1 3.9Å; E222-H476 PolarHBondContact OE2-CE1 2.85Å; E222-H476 IonicContact OE2-ND1 2.7Å; E222-H476 IonicContact OE2-NE2 3.46Å
223	G	81.4	Confident	87.2	Confident	0 Å²	0	67.6 Å²	67.6	0%	0	36%	0.356	C	S	.	.	T	Hydrogen-bonded Turn	trans	-79.9	5.2	175.9	0	0	0	0	0	114.9	K219 R225 C475	K219-G223 PolarHBondContact O-N 3.49Å; G223-R225 PolarHBondContact O-N 3.01Å; G223-C475 PolarHBondContact N-O 3.12Å
224	N	83.7	Confident	86.8	Confident	97 Å²	97	63.4 Å²	63.4	52%	0.519	34%	0.336	S	S	.	.	T	Hydrogen-bonded Turn	trans	49.4	39.7	-179.4	-161.2	31.4	0	0	0	114.2	V220 K221 E222 I477	V220-N224 PolarHBondContact O-N 2.93Å; K221-N224 PolarHBondContact O-N 3.04Å; E222-N224 PolarHBondContact O-N 2.93Å; N224-I477 HydrophobicContact CB-CD1 4.05Å
225	R	84	Confident	86.4	Confident	6 Å²	6	61.5 Å²	61.5	2%	0.023	32%	0.321	C	S	.	.			trans	-84.9	-16.4	179.1	-67.8	-64	177.5	166.2	-7.5	113.7	Y78 T79 G81 T82 V220 G223 S227 L298 F301 L471 P472	Y78-R225 PolarHBondContact O-NH1 3.28Å; T79-R225 VanDerWaalsContact C-NH1 3.26Å; T79-R225 PolarHBondContact O-NH1 2.86Å; G81-R225 WeakPolarHBondContact CA-O 3.47Å; T82-R225 PolarHBondContact N-O 3.46Å; T82-R225 PolarHBondContact OG1-O 2.94Å; V220-R225 HydrophobicContact CG1-CB 4.31Å; V220-R225 PolarHBondContact O-N 3.29Å; G223-R225 PolarHBondContact O-N 3.01Å; R225-S227 PolarHBondContact O-N 3.36Å; R225-L298 HydrophobicContact CB-CD2 4.17Å; R225-F301 HydrophobicContact CB-CD1 4.36Å; R225-F301 HydrophobicContact CB-CE1 4.46Å; R225-F301 HydrophobicContact CG-CD1 3.48Å; R225-F301 VanDerWaalsContact CG-CD1 3.48Å; R225-F301 HydrophobicContact CG-CD2 3.84Å; R225-F301 HydrophobicContact CG-CE1 3.42Å; R225-F301 VanDerWaalsContact CG-CE1 3.42Å; R225-F301 HydrophobicContact CG-CE2 3.82Å; R225-F301 HydrophobicContact CG-CG 3.67Å; R225-F301 HydrophobicContact CG-CZ 3.59Å; R225-L471 PolarHBondContact NH2-O 2.94Å; R225-L471 VanDerWaalsContact NH2-O 3.09Å; R225-P472 PolarHBondContact NH2-O 3.46Å
226	L	85.3	Confident	86.1	Confident	58 Å²	58	60.5 Å²	60.5	30%	0.304	32%	0.318	S	S	.	.	S	Bend	trans	-77.5	98.9	172.5	-61.1	177.9	0	0	0	109	T82 W217 V220 L298	T82-L226 HydrophobicContact CG2-CD2 4.08Å; W217-L226 HydrophobicContact CH2-CD1 3.75Å; W217-L226 HydrophobicContact CH2-CD2 4.29Å; W217-L226 HydrophobicContact CZ2-CD1 3.84Å; W217-L226 HydrophobicContact CZ3-CD1 4.3Å; W217-L226 HydrophobicContact CZ3-CD2 4.32Å; V220-L226 HydrophobicContact CG1-CD1 4.25Å; V220-L226 HydrophobicContact CG1-CD2 3.69Å; V220-L226 HydrophobicContact CG1-CG 3.65Å; L226-L298 HydrophobicContact CD2-CD1 4.36Å
227	S	79.6	Confident	85.6	Confident	31 Å²	31	64.4 Å²	64.4	22%	0.217	34%	0.336	C	S	.	.			trans	-78.1	126.5	176.5	-49.9	0	0	0	0	109.9	T82 Q83 R225	T82-S227 PolarHBondContact N-OG 2.91Å; T82-S227 PolarHBondContact OG1-N 2.88Å; Q83-S227 VanDerWaalsContact CG-CB 3.4Å; Q83-S227 VanDerWaalsContact CG-OG 3.23Å; Q83-S227 WeakPolarHBondContact CG-OG 3.47Å; Q83-S227 PolarHBondContact N-OG 3.48Å; R225-S227 PolarHBondContact O-N 3.36Å
228	G	80.1	Confident	85.1	Confident	58 Å²	58	59.9 Å²	59.9	60%	0.598	32%	0.319	S	S	*	.			trans	-69.4	-178.2	168.1	0	0	0	0	0	112.4	F86 D230	F86-G228 WeakPolarHBondContact CE2-O 3.44Å; G228-D230 PolarHBondContact O-N 3.32Å; G228-D230 VanDerWaalsContact O-N 3.15Å
229	L	81.9	Confident	84.9	Confident	95 Å²	95	55.3 Å²	55.3	50%	0.497	30%	0.302	S	S	.	.			trans	-71.6	104.3	175.2	-170.9	74	0	0	0	110.2	F86 L231 F241	F86-L229 HydrophobicContact CD1-CD1 4.02Å; F86-L229 HydrophobicContact CE1-CD1 3.58Å; F86-L229 HydrophobicContact CZ-CB 4.3Å; F86-L229 HydrophobicContact CZ-CD1 3.93Å; L229-L231 HydrophobicContact CD2-CD1 4.1Å; L229-L231 HydrophobicContact CD2-CD2 3.78Å; L229-L231 HydrophobicContact CD2-CG 3.94Å; L229-L231 HydrophobicContact CG-CD2 3.91Å; L229-L231 HydrophobicContact CG-CG 4.03Å; L229-L231 PolarHBondContact O-N 2.86Å; L229-F241 HydrophobicContact CD1-CB 3.89Å; L229-F241 HydrophobicContact CD1-CD2 3.47Å; L229-F241 VanDerWaalsContact CD1-CD2 3.47Å; L229-F241 HydrophobicContact CD1-CE2 4.22Å; L229-F241 HydrophobicContact CD1-CG 3.84Å; L229-F241 HydrophobicContact CG-CB 4.48Å
230	D	84.6	Confident	85	Confident	59 Å²	59	53.4 Å²	53.4	32%	0.316	29%	0.294	S	S	.	.			trans	-85.4	108.6	172.4	-171.9	-10.4	0	0	0	110.3	G228 N232 F241	G228-D230 PolarHBondContact O-N 3.32Å; G228-D230 VanDerWaalsContact O-N 3.15Å; D230-N232 WeakPolarHBondContact OD1-CB 3.21Å; D230-N232 PolarHBondContact OD1-N 2.62Å; D230-F241 VanDerWaalsContact O-CB 3.27Å; D230-F241 WeakPolarHBondContact O-CB 3.43Å; D230-F241 PolarHBondContact O-N 3.44Å
231	L	87.9	Confident	84.9	Confident	93 Å²	93	56.1 Å²	56.1	49%	0.487	31%	0.306	S	S	.	.			trans	-94.7	12.8	-179.3	-67.9	177.6	0	0	0	113.6	L229 P233 F241 W242	L229-L231 HydrophobicContact CD2-CD1 4.1Å; L229-L231 HydrophobicContact CD2-CD2 3.78Å; L229-L231 HydrophobicContact CD2-CG 3.94Å; L229-L231 HydrophobicContact CG-CD2 3.91Å; L229-L231 HydrophobicContact CG-CG 4.03Å; L229-L231 PolarHBondContact O-N 2.86Å; L231-P233 VanDerWaalsContact O-CD 3.31Å; L231-P233 WeakPolarHBondContact O-CD 3.3Å; L231-F241 HydrophobicContact CD2-CB 3.99Å; L231-F241 HydrophobicContact CD2-CD1 3.78Å; L231-F241 HydrophobicContact CD2-CG 4.03Å; L231-W242 PolarHBondContact O-NE1 2.64Å
232	N	87.3	Confident	85.1	Confident	57 Å²	57	54 Å²	54	31%	0.305	29%	0.294	S	S	.	.			trans	-59.5	118.1	176	-176.7	3.3	0	0	0	110.8	D230 D234 T240	D230-N232 WeakPolarHBondContact OD1-CB 3.21Å; D230-N232 PolarHBondContact OD1-N 2.62Å; N232-D234 PolarHBondContact O-N 2.94Å; N232-D234 PolarHBondContact OD1-N 3.39Å; N232-D234 VanDerWaalsContact OD1-N 3.13Å; N232-T240 HydrophobicContact CB-CG2 4.25Å; N232-T240 WeakPolarHBondContact O-CG2 3.34Å; N232-T240 PolarHBondContact O-OG1 3.46Å
233	P	86.3	Confident	85.3	Confident	99 Å²	99	50.7 Å²	50.7	64%	0.643	28%	0.278	S	S	*	.			trans	-78.7	-1.6	-176.7	33.5	-37	0	0	0	113.8	L231 P235	L231-P233 VanDerWaalsContact O-CD 3.31Å; L231-P233 WeakPolarHBondContact O-CD 3.3Å; P233-P235 VanDerWaalsContact O-CD 3.28Å; P233-P235 WeakPolarHBondContact O-CD 3.5Å
234	D	85.3	Confident	85.8	Confident	20 Å²	20	50.8 Å²	50.8	11%	0.107	28%	0.279	C	S	.	.			trans	-62.4	116.3	179.6	-166.2	-35.2	0	0	0	110.9	N232 T236 E237 R499	N232-D234 PolarHBondContact O-N 2.94Å; N232-D234 PolarHBondContact OD1-N 3.39Å; N232-D234 VanDerWaalsContact OD1-N 3.13Å; D234-T236 VanDerWaalsContact CG-OG1 3.26Å; D234-T236 PolarHBondContact O-N 2.7Å; D234-T236 WeakPolarHBondContact OD1-CB 3.4Å; D234-T236 PolarHBondContact OD1-N 3Å; D234-T236 PolarHBondContact OD1-OG1 3.41Å; D234-E237 HydrophobicContact CB-CG 4.13Å; D234-E237 PolarHBondContact O-N 3.13Å; D234-R499 IonicContact OD1-NH2 3.91Å; D234-R499 IonicContact OD2-CZ 3.89Å; D234-R499 IonicContact OD2-NH2 2.82Å; D234-R499 PolarHBondContact OD2-NH2 3.37Å
235	P	84.9	Confident	86.2	Confident	56 Å²	56	46.6 Å²	46.6	36%	0.364	26%	0.258	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.8	-7.8	-176.4	32.6	-37.8	0	0	0	113.6	P233 L503 S504	P233-P235 VanDerWaalsContact O-CD 3.28Å; P233-P235 WeakPolarHBondContact O-CD 3.5Å; P235-L503 HydrophobicContact CB-CD1 3.86Å; P235-L503 HydrophobicContact CG-CD1 4.36Å; P235-S504 WeakPolarHBondContact O-CB 3.47Å; P235-S504 PolarHBondContact O-N 3.45Å
236	T	84.7	Confident	86.6	Confident	30 Å²	30	48.8 Å²	48.8	18%	0.184	27%	0.272	C	S	.	.	T	Hydrogen-bonded Turn	trans	-84.4	-17	175.5	65.3	0	0	0	0	112.8	D234 R238 R499 S502	D234-T236 VanDerWaalsContact CG-OG1 3.26Å; D234-T236 PolarHBondContact O-N 2.7Å; D234-T236 WeakPolarHBondContact OD1-CB 3.4Å; D234-T236 PolarHBondContact OD1-N 3Å; D234-T236 PolarHBondContact OD1-OG1 3.41Å; T236-R238 PolarHBondContact O-N 2.89Å; T236-R499 HydrophobicContact CG2-CG 3.83Å; T236-R499 WeakPolarHBondContact CG2-O 3.29Å; T236-S502 CarbonylContact C-O 3.51Å; T236-S502 VanDerWaalsContact CA-O 3.26Å; T236-S502 WeakPolarHBondContact CA-O 3.26Å; T236-S502 WeakPolarHBondContact CB-O 3.07Å
237	E	82.4	Confident	87	Confident	89 Å²	89	46 Å²	46	42%	0.416	26%	0.258	S	S	.	.	S	Bend	trans	-67.2	133.6	173.5	-72.5	-62.7	162.3	0	0	110.2	D234 H239 T240 T243 S504	D234-E237 HydrophobicContact CB-CG 4.13Å; D234-E237 PolarHBondContact O-N 3.13Å; E237-H239 PolarHBondContact O-N 3.18Å; E237-T240 HydrophobicContact CB-CG2 3.6Å; E237-T240 HydrophobicContact CG-CG2 4.35Å; E237-T243 WeakPolarHBondContact O-CG2 3.48Å; E237-S504 VanDerWaalsContact O-CB 3.27Å; E237-S504 WeakPolarHBondContact O-CB 3.43Å
238	R	82.7	Confident	87.7	Confident	45 Å²	45	44.5 Å²	44.5	17%	0.17	25%	0.248	C	C	.	.	S	Bend	trans	-54.6	-57	-173.8	177.1	-168.7	164.4	118.4	24.3	111.1	E76 H80 T236 S504 Y505	E76-R238 IonicContact OE1-CZ 3.32Å; E76-R238 IonicContact OE1-NE 3.14Å; E76-R238 PolarHBondContact OE1-NE 3.21Å; E76-R238 VanDerWaalsContact OE1-NE 3.07Å; E76-R238 IonicContact OE1-NH1 3.91Å; E76-R238 IonicContact OE1-NH2 3.78Å; E76-R238 PolarHBondContact OE1-NH2 2.85Å; E76-R238 IonicContact OE2-CZ 3.79Å; E76-R238 IonicContact OE2-NH1 2.77Å; E76-R238 IonicContact OE2-NH2 3.44Å; E76-R238 PolarHBondContact OE2-NH2 3.27Å; H80-R238 PolarHBondContact CE1-NH1 3.04Å; H80-R238 VanDerWaalsContact CE1-NH1 3.29Å; H80-R238 PolarHBondContact NE2-NH1 3.28Å; T236-R238 PolarHBondContact O-N 2.89Å; R238-S504 PolarHBondContact O-OG 2.95Å; R238-Y505 HydrophobicContact CG-CE1 4.22Å
239	H	88.1	Confident	88.5	Confident	6 Å²	6	42.4 Å²	42.4	3%	0.028	22%	0.223	C	C	.	.	S	Bend	trans	-135.1	111.9	-177.8	-69.8	160.6	0	0	0	111.3	E76 Q83 Y84 E237 T243 L244 Y505	E76-H239 IonicContact OE1-CE1 2.79Å; E76-H239 PolarHBondContact OE1-CE1 3.35Å; E76-H239 IonicContact OE1-ND1 3.5Å; E76-H239 PolarHBondContact OE1-ND1 2.89Å; Q83-H239 HydrophobicContact CB-CB 4.01Å; Y84-H239 AromaticContact CD2-CE1 3.68Å; Y84-H239 AromaticContact CD2-NE2 3.97Å; E237-H239 PolarHBondContact O-N 3.18Å; H239-T243 WeakPolarHBondContact CA-OG1 3.1Å; H239-L244 HydrophobicContact CB-CD1 3.89Å; H239-L244 HydrophobicContact CB-CG 4.29Å; H239-Y505 PolarHBondContact CE1-OH 2.88Å; H239-Y505 AromaticContact NE2-CZ 3.58Å; H239-Y505 PolarHBondContact NE2-OH 3Å
240	T	89.4	Confident	89.2	Confident	4 Å²	4	40.3 Å²	40.3	3%	0.025	21%	0.21	C	C	.	.			trans	-128.5	173.3	165.9	69.1	0	0	0	0	108.7	N232 E237 W242 T243 L244	N232-T240 HydrophobicContact CB-CG2 4.25Å; N232-T240 WeakPolarHBondContact O-CG2 3.34Å; N232-T240 PolarHBondContact O-OG1 3.46Å; E237-T240 HydrophobicContact CB-CG2 3.6Å; E237-T240 HydrophobicContact CG-CG2 4.35Å; T240-W242 PolarHBondContact O-N 2.96Å; T240-W242 PolarHBondContact OG1-N 3.05Å; T240-T243 PolarHBondContact N-OG1 3.46Å; T240-T243 PolarHBondContact O-N 3.33Å; T240-T243 PolarHBondContact O-OG1 3.19Å; T240-T243 VanDerWaalsContact O-OG1 3.13Å; T240-T243 WeakPolarHBondContact OG1-CG2 3.37Å; T240-T243 PolarHBondContact OG1-N 3.49Å; T240-L244 WeakPolarHBondContact O-CB 3.48Å; T240-L244 PolarHBondContact O-N 3.28Å
241	F	89.6	Confident	89.6	Confident	57 Å²	57	37.7 Å²	37.7	25%	0.25	20%	0.196	C	C	.	.	H	α-helix	trans	-55.1	-38	171.1	175.5	-103.1	0	0	0	111.8	L229 D230 L231 G245	L229-F241 HydrophobicContact CD1-CB 3.89Å; L229-F241 HydrophobicContact CD1-CD2 3.47Å; L229-F241 VanDerWaalsContact CD1-CD2 3.47Å; L229-F241 HydrophobicContact CD1-CE2 4.22Å; L229-F241 HydrophobicContact CD1-CG 3.84Å; L229-F241 HydrophobicContact CG-CB 4.48Å; D230-F241 VanDerWaalsContact O-CB 3.27Å; D230-F241 WeakPolarHBondContact O-CB 3.43Å; D230-F241 PolarHBondContact O-N 3.44Å; L231-F241 HydrophobicContact CD2-CB 3.99Å; L231-F241 HydrophobicContact CD2-CD1 3.78Å; L231-F241 HydrophobicContact CD2-CG 4.03Å; F241-G245 WeakPolarHBondContact O-CA 3.46Å; F241-G245 PolarHBondContact O-N 3.04Å
242	W	91.1	Very high	90	Very high	105 Å²	105	33.8 Å²	33.8	40%	0.398	18%	0.175	S	C	.	.	I	π-helix	trans	-71	-44.4	-179.6	-59.6	106.4	0	0	0	112.3	L231 T240 V246 G247 W507	L231-W242 PolarHBondContact O-NE1 2.64Å; T240-W242 PolarHBondContact O-N 2.96Å; T240-W242 PolarHBondContact OG1-N 3.05Å; W242-V246 HydrophobicContact CE3-CG2 3.82Å; W242-V246 HydrophobicContact CZ3-CG2 4.3Å; W242-V246 WeakPolarHBondContact O-CA 3.4Å; W242-V246 VanDerWaalsContact O-CB 3.29Å; W242-V246 WeakPolarHBondContact O-CB 3.24Å; W242-V246 PolarHBondContact O-N 3.37Å; W242-G247 PolarHBondContact O-N 3.44Å; W242-W507 HydrophobicContact CB-CZ2 4.3Å; W242-W507 WeakPolarHBondContact O-CZ2 3.43Å
243	T	91.5	Very high	90.4	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	16%	0.164	C	C	.	.	I	π-helix	trans	-67.6	-43.4	-178.7	67	0	0	0	0	110.6	E237 H239 T240 G247 G248 M506 W507	E237-T243 WeakPolarHBondContact O-CG2 3.48Å; H239-T243 WeakPolarHBondContact CA-OG1 3.1Å; T240-T243 PolarHBondContact N-OG1 3.46Å; T240-T243 PolarHBondContact O-N 3.33Å; T240-T243 PolarHBondContact O-OG1 3.19Å; T240-T243 VanDerWaalsContact O-OG1 3.13Å; T240-T243 WeakPolarHBondContact OG1-CG2 3.37Å; T240-T243 PolarHBondContact OG1-N 3.49Å; T243-G247 CarbonylContact O-C 3.37Å; T243-G247 WeakPolarHBondContact O-CA 3.17Å; T243-G247 PolarHBondContact O-N 2.94Å; T243-G248 PolarHBondContact O-N 3.13Å; T243-G248 VanDerWaalsContact O-N 3.12Å; T243-M506 VanDerWaalsContact O-CB 3.3Å; T243-M506 WeakPolarHBondContact O-CB 3.36Å; T243-W507 VanDerWaalsContact CG2-NE1 3.32Å
244	L	92.1	Very high	90.8	Very high	1 Å²	1	27.1 Å²	27.1	1%	0.005	14%	0.135	C	C	.	.	I	π-helix	trans	-80.5	-46.5	-178.1	-69.6	171.4	0	0	0	112.2	Q83 Y84 F86 I87 A90 H239 T240 G248 M506	Q83-L244 WeakPolarHBondContact O-CD1 3.39Å; Y84-L244 HydrophobicContact CD2-CD2 4.11Å; Y84-L244 HydrophobicContact CE2-CD2 4.46Å; F86-L244 HydrophobicContact CB-CB 4.29Å; F86-L244 HydrophobicContact CB-CD1 4.13Å; I87-L244 HydrophobicContact CB-CD2 4.3Å; A90-L244 WeakPolarHBondContact CB-O 3.05Å; H239-L244 HydrophobicContact CB-CD1 3.89Å; H239-L244 HydrophobicContact CB-CG 4.29Å; T240-L244 WeakPolarHBondContact O-CB 3.48Å; T240-L244 PolarHBondContact O-N 3.28Å; L244-G248 WeakPolarHBondContact O-CA 3.4Å; L244-G248 PolarHBondContact O-N 3.02Å; L244-M506 HydrophobicContact CD2-CE 4.14Å; L244-M506 HydrophobicContact CD2-CG 4.15Å; L244-M506 HydrophobicContact CD2-SD 4.32Å
245	G	91.6	Very high	91.2	Very high	9 Å²	9	26.9 Å²	26.9	9%	0.093	13%	0.133	C	C	.	.	I	π-helix	trans	-74.2	-44	-177.3	0	0	0	0	0	113.3	F241 V249	F241-G245 WeakPolarHBondContact O-CA 3.46Å; F241-G245 PolarHBondContact O-N 3.04Å; G245-V249 VanDerWaalsContact O-CG2 3.23Å; G245-V249 WeakPolarHBondContact O-CG2 3.04Å
246	V	92.2	Very high	91.6	Very high	52 Å²	52	24.3 Å²	24.3	32%	0.315	12%	0.116	S	C	.	.	I	π-helix	trans	-96.1	-51.1	-179	-175.8	0	0	0	0	111.6	W242 G248 V249 W507	W242-V246 HydrophobicContact CE3-CG2 3.82Å; W242-V246 HydrophobicContact CZ3-CG2 4.3Å; W242-V246 WeakPolarHBondContact O-CA 3.4Å; W242-V246 VanDerWaalsContact O-CB 3.29Å; W242-V246 WeakPolarHBondContact O-CB 3.24Å; W242-V246 PolarHBondContact O-N 3.37Å; V246-G248 VanDerWaalsContact C-N 3.25Å; V246-G248 PolarHBondContact O-N 3.4Å; V246-V249 WeakPolarHBondContact O-CB 3.13Å; V246-V249 PolarHBondContact O-N 2.9Å; V246-W507 HydrophobicContact CB-CH2 3.75Å; V246-W507 HydrophobicContact CB-CZ2 4.4Å; V246-W507 HydrophobicContact CB-CZ3 4.48Å; V246-W507 HydrophobicContact CG1-CH2 3.61Å; V246-W507 HydrophobicContact CG1-CZ3 4.04Å
247	G	93.2	Very high	92.1	Very high	0 Å²	0	23 Å²	23	0%	0	11%	0.108	C	C	.	.	I	π-helix	trans	-58.1	-40.8	175.3	0	0	0	0	0	111.8	W242 T243 V249 F250 L251 M506	W242-G247 PolarHBondContact O-N 3.44Å; T243-G247 CarbonylContact O-C 3.37Å; T243-G247 WeakPolarHBondContact O-CA 3.17Å; T243-G247 PolarHBondContact O-N 2.94Å; G247-V249 VanDerWaalsContact C-N 3.25Å; G247-V249 PolarHBondContact O-N 3.04Å; G247-F250 PolarHBondContact O-N 3.38Å; G247-L251 PolarHBondContact O-N 3.25Å; G247-M506 CarbonylContact C-O 3.54Å; G247-M506 WeakPolarHBondContact CA-O 3.45Å
248	G	94.6	Very high	92.7	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-60.6	-26.6	173.7	0	0	0	0	0	114.6	T243 L244 V246 L251 M252	T243-G248 PolarHBondContact O-N 3.13Å; T243-G248 VanDerWaalsContact O-N 3.12Å; L244-G248 WeakPolarHBondContact O-CA 3.4Å; L244-G248 PolarHBondContact O-N 3.02Å; V246-G248 VanDerWaalsContact C-N 3.25Å; V246-G248 PolarHBondContact O-N 3.4Å; G248-L251 WeakPolarHBondContact O-CB 3.26Å; G248-L251 PolarHBondContact O-N 3.49Å; G248-M252 WeakPolarHBondContact O-CB 3.21Å; G248-M252 VanDerWaalsContact O-CG 3.26Å; G248-M252 WeakPolarHBondContact O-CG 3.47Å; G248-M252 PolarHBondContact O-N 3.11Å
249	V	96.3	Very high	93.3	Very high	14 Å²	14	16.9 Å²	16.9	9%	0.085	8%	0.082	C	C	.	.	H	α-helix	trans	-65.1	-43.7	176.3	168	0	0	0	0	110.3	A90 L93 I97 G245 V246 G247 L251 M252 L253	A90-V249 HydrophobicContact CB-CG2 4.06Å; L93-V249 HydrophobicContact CB-CG1 4.26Å; L93-V249 HydrophobicContact CB-CG2 3.83Å; L93-V249 HydrophobicContact CD1-CG2 4.31Å; I97-V249 HydrophobicContact CD1-CG1 4.44Å; G245-V249 VanDerWaalsContact O-CG2 3.23Å; G245-V249 WeakPolarHBondContact O-CG2 3.04Å; V246-V249 WeakPolarHBondContact O-CB 3.13Å; V246-V249 PolarHBondContact O-N 2.9Å; G247-V249 VanDerWaalsContact C-N 3.25Å; G247-V249 PolarHBondContact O-N 3.04Å; V249-L251 VanDerWaalsContact C-N 3.31Å; V249-L251 PolarHBondContact O-N 3.22Å; V249-M252 PolarHBondContact O-N 3.14Å; V249-L253 HydrophobicContact CG1-CD1 3.93Å; V249-L253 HydrophobicContact CG1-CG 4.19Å; V249-L253 WeakPolarHBondContact O-CB 3.42Å; V249-L253 VanDerWaalsContact O-CG 3.23Å; V249-L253 WeakPolarHBondContact O-CG 3.43Å; V249-L253 PolarHBondContact O-N 2.99Å
250	F	96.8	Very high	93.6	Very high	50 Å²	50	16.6 Å²	16.6	22%	0.219	8%	0.08	C	C	.	.	H	α-helix	trans	-63.6	-39.5	176.2	-70.8	-87.4	0	0	0	111.8	G247 L253 S254 L425 A509 G510 C513	G247-F250 PolarHBondContact O-N 3.38Å; F250-L253 PolarHBondContact O-N 3.39Å; F250-S254 PolarHBondContact O-N 3.24Å; F250-L425 HydrophobicContact CB-CD2 4.37Å; F250-L425 HydrophobicContact CD1-CD2 4.12Å; F250-L425 VanDerWaalsContact O-CD2 3.32Å; F250-L425 WeakPolarHBondContact O-CD2 3.3Å; F250-A509 HydrophobicContact CB-CB 3.81Å; F250-G510 VanDerWaalsContact CG-CA 3.46Å; F250-C513 HydrophobicContact CD1-CB 4.27Å
251	L	94.5	Very high	93.8	Very high	4 Å²	4	16.5 Å²	16.5	2%	0.021	8%	0.08	C	C	.	.	H	α-helix	trans	-59.8	-50.3	172.9	-179.9	70.4	0	0	0	110.8	G247 G248 V249 L253 S254 L255 L414 F417 M506	G247-L251 PolarHBondContact O-N 3.25Å; G248-L251 WeakPolarHBondContact O-CB 3.26Å; G248-L251 PolarHBondContact O-N 3.49Å; V249-L251 VanDerWaalsContact C-N 3.31Å; V249-L251 PolarHBondContact O-N 3.22Å; L251-L253 VanDerWaalsContact C-N 3.34Å; L251-L253 PolarHBondContact O-N 3.44Å; L251-S254 WeakPolarHBondContact O-CB 3.4Å; L251-S254 PolarHBondContact O-N 3.2Å; L251-S254 VanDerWaalsContact O-N 3.12Å; L251-S254 PolarHBondContact O-OG 3.17Å; L251-L255 HydrophobicContact CG-CD1 4.24Å; L251-L255 WeakPolarHBondContact O-CG 3.32Å; L251-L255 PolarHBondContact O-N 3.21Å; L251-L255 VanDerWaalsContact O-N 3.09Å; L251-L414 HydrophobicContact CD2-CD2 3.51Å; L251-F417 HydrophobicContact CD1-CB 3.54Å; L251-M506 HydrophobicContact CD2-CE 3.92Å; L251-M506 HydrophobicContact CD2-SD 4.4Å
252	M	94.8	Very high	94	Very high	12 Å²	12	13.8 Å²	13.8	6%	0.059	7%	0.068	C	C	.	.	H	α-helix	trans	-63	-39.1	179.7	-69.3	-57.7	121.5	0	0	112.7	I87 Y91 G248 V249 S254 L255 Y256	I87-M252 HydrophobicContact CD1-CE 4.29Å; Y91-M252 HydrophobicContact CD1-CE 4.21Å; Y91-M252 HydrophobicContact CD1-CG 3.84Å; Y91-M252 HydrophobicContact CD1-SD 3.5Å; Y91-M252 VanDerWaalsContact CD1-SD 3.5Å; Y91-M252 HydrophobicContact CE1-CE 3.67Å; Y91-M252 HydrophobicContact CE1-CG 4.27Å; Y91-M252 HydrophobicContact CE1-SD 3.49Å; Y91-M252 WeakPolarHBondContact CE1-SD 3.41Å; G248-M252 WeakPolarHBondContact O-CB 3.21Å; G248-M252 VanDerWaalsContact O-CG 3.26Å; G248-M252 WeakPolarHBondContact O-CG 3.47Å; G248-M252 PolarHBondContact O-N 3.11Å; V249-M252 PolarHBondContact O-N 3.14Å; M252-S254 VanDerWaalsContact C-N 3.32Å; M252-S254 PolarHBondContact O-N 3.46Å; M252-L255 HydrophobicContact CE-CD1 3.92Å; M252-L255 PolarHBondContact O-N 2.64Å; M252-L255 HydrophobicContact SD-CD1 4.34Å; M252-Y256 PolarHBondContact O-N 3.15Å; M252-Y256 HydrophobicContact SD-CD2 4.4Å; M252-Y256 HydrophobicContact SD-CE2 4.3Å
253	L	96	Very high	94.2	Very high	14 Å²	14	8.9 Å²	8.9	7%	0.073	5%	0.05	C	C	.	.	H	α-helix	trans	-63	-38.2	173.7	-73	177.3	0	0	0	112	I97 P98 F102 V249 F250 L251 L255 G257 V258 L425	I97-L253 HydrophobicContact CB-CD2 3.8Å; I97-L253 HydrophobicContact CD1-CD1 4.41Å; I97-L253 HydrophobicContact CD1-CD2 4.44Å; I97-L253 HydrophobicContact CG2-CD2 3.61Å; P98-L253 HydrophobicContact CG-CD2 3.77Å; F102-L253 HydrophobicContact CE2-CD2 4.22Å; V249-L253 HydrophobicContact CG1-CD1 3.93Å; V249-L253 HydrophobicContact CG1-CG 4.19Å; V249-L253 WeakPolarHBondContact O-CB 3.42Å; V249-L253 VanDerWaalsContact O-CG 3.23Å; V249-L253 WeakPolarHBondContact O-CG 3.43Å; V249-L253 PolarHBondContact O-N 2.99Å; F250-L253 PolarHBondContact O-N 3.39Å; L251-L253 VanDerWaalsContact C-N 3.34Å; L251-L253 PolarHBondContact O-N 3.44Å; L253-L255 VanDerWaalsContact C-N 3.27Å; L253-L255 PolarHBondContact O-N 2.95Å; L253-G257 WeakPolarHBondContact O-CA 3.45Å; L253-G257 PolarHBondContact O-N 3.29Å; L253-V258 PolarHBondContact O-N 2.96Å; L253-L425 HydrophobicContact CB-CD1 3.81Å; L253-L425 HydrophobicContact CB-CD2 3.63Å; L253-L425 HydrophobicContact CB-CG 4.39Å; L253-L425 HydrophobicContact CD1-CD2 4.48Å
254	S	95.3	Very high	94.2	Very high	2 Å²	2	8.9 Å²	8.9	1%	0.014	5%	0.05	C	C	.	.	H	α-helix	trans	-65	-34.2	175.3	79.5	0	0	0	0	112	F250 L251 M252 N259	F250-S254 PolarHBondContact O-N 3.24Å; L251-S254 WeakPolarHBondContact O-CB 3.4Å; L251-S254 PolarHBondContact O-N 3.2Å; L251-S254 VanDerWaalsContact O-N 3.12Å; L251-S254 PolarHBondContact O-OG 3.17Å; M252-S254 VanDerWaalsContact C-N 3.32Å; M252-S254 PolarHBondContact O-N 3.46Å; S254-N259 WeakPolarHBondContact O-CB 3.49Å; S254-N259 PolarHBondContact O-N 3.06Å
255	L	93.4	Very high	94.3	Very high	14 Å²	14	8.9 Å²	8.9	7%	0.073	5%	0.05	C	C	.	.	H	α-helix	trans	-79.8	-50.7	-179.2	-66.9	174	0	0	0	112.7	F64 L251 M252 L253 N259 Q262 F417	F64-L255 HydrophobicContact CD1-CD2 3.86Å; F64-L255 HydrophobicContact CE1-CD2 3.45Å; F64-L255 VanDerWaalsContact CE1-CD2 3.45Å; F64-L255 HydrophobicContact CZ-CD2 3.9Å; L251-L255 HydrophobicContact CG-CD1 4.24Å; L251-L255 WeakPolarHBondContact O-CG 3.32Å; L251-L255 PolarHBondContact O-N 3.21Å; L251-L255 VanDerWaalsContact O-N 3.09Å; M252-L255 HydrophobicContact CE-CD1 3.92Å; M252-L255 PolarHBondContact O-N 2.64Å; M252-L255 HydrophobicContact SD-CD1 4.34Å; L253-L255 VanDerWaalsContact C-N 3.27Å; L253-L255 PolarHBondContact O-N 2.95Å; L255-N259 WeakPolarHBondContact O-CB 3.34Å; L255-Q262 WeakPolarHBondContact O-CG 3.19Å; L255-F417 HydrophobicContact CD2-CD1 3.27Å; L255-F417 HydrophobicContact CD2-CD2 4.06Å; L255-F417 HydrophobicContact CD2-CE1 3.35Å; L255-F417 HydrophobicContact CD2-CE2 4.11Å; L255-F417 HydrophobicContact CD2-CG 3.7Å; L255-F417 HydrophobicContact CD2-CZ 3.81Å; L255-F417 HydrophobicContact CG-CD1 4.42Å
256	Y	94.4	Very high	94.4	Very high	3 Å²	3	8.7 Å²	8.7	1%	0.012	5%	0.047	C	C	.	.	H	α-helix	trans	-100.5	-19.1	-172.5	-72.7	-77.4	0	0	0	114	L95 M252 Q262 Y266 V282 L286	L95-Y256 HydrophobicContact CD2-CD1 3.92Å; L95-Y256 HydrophobicContact CD2-CD2 3.92Å; L95-Y256 HydrophobicContact CD2-CE1 4.33Å; L95-Y256 HydrophobicContact CD2-CE2 4.33Å; L95-Y256 HydrophobicContact CD2-CG 3.69Å; M252-Y256 PolarHBondContact O-N 3.15Å; M252-Y256 HydrophobicContact SD-CD2 4.4Å; M252-Y256 HydrophobicContact SD-CE2 4.3Å; Y256-Q262 HydrophobicContact CD1-CG 3.95Å; Y256-Q262 HydrophobicContact CE1-CG 4.32Å; Y256-Y266 WeakPolarHBondContact CD1-OH 3.5Å; Y256-Y266 WeakPolarHBondContact O-CE2 3.31Å; Y256-V282 HydrophobicContact CE1-CG1 3.95Å; Y256-L286 HydrophobicContact CE2-CD1 3.97Å
257	G	93.6	Very high	94.4	Very high	2 Å²	2	6.4 Å²	6.4	2%	0.021	3%	0.033	C	C	.	.	T	Hydrogen-bonded Turn	trans	-87.7	-43.3	-179.1	0	0	0	0	0	113.9	L253	L253-G257 WeakPolarHBondContact O-CA 3.45Å; L253-G257 PolarHBondContact O-N 3.29Å
258	V	94.9	Very high	94.3	Very high	1 Å²	1	6.4 Å²	6.4	1%	0.006	3%	0.033	C	C	.	.	S	Bend	trans	-131	-10.4	-166.3	-59.3	0	0	0	0	114.8	F102 L253 Q260 I424 L425 F428	F102-V258 HydrophobicContact CD1-CG1 3.74Å; F102-V258 HydrophobicContact CE1-CG1 3.54Å; L253-V258 PolarHBondContact O-N 2.96Å; V258-Q260 PolarHBondContact O-N 3.25Å; V258-I424 HydrophobicContact CB-CG2 4.48Å; V258-I424 HydrophobicContact CG2-CG2 4.09Å; V258-L425 HydrophobicContact CG1-CD1 4.11Å; V258-L425 HydrophobicContact CG2-CB 4.22Å; V258-L425 HydrophobicContact CG2-CD1 4.29Å; V258-F428 HydrophobicContact CB-CD2 3.86Å; V258-F428 HydrophobicContact CB-CE2 4.17Å; V258-F428 HydrophobicContact CB-CG 4.12Å; V258-F428 HydrophobicContact CG1-CB 3.56Å; V258-F428 HydrophobicContact CG1-CD1 4.08Å; V258-F428 HydrophobicContact CG1-CD2 3.79Å; V258-F428 HydrophobicContact CG1-CE2 4.48Å; V258-F428 HydrophobicContact CG1-CG 3.54Å
259	N	95.4	Very high	94.2	Very high	4 Å²	4	6.4 Å²	6.4	2%	0.021	3%	0.033	C	C	.	.			trans	-68.1	126.5	176.7	-167.5	-59.1	0	0	0	110.1	S254 L255 A261 Q262 V263	S254-N259 WeakPolarHBondContact O-CB 3.49Å; S254-N259 PolarHBondContact O-N 3.06Å; L255-N259 WeakPolarHBondContact O-CB 3.34Å; N259-A261 PolarHBondContact O-N 2.91Å; N259-A261 VanDerWaalsContact O-N 3.13Å; N259-A261 WeakPolarHBondContact OD1-CB 3.37Å; N259-A261 PolarHBondContact OD1-N 3.26Å; N259-Q262 PolarHBondContact O-N 3.03Å; N259-V263 WeakPolarHBondContact O-CG2 3.34Å; N259-V263 PolarHBondContact O-N 3.32Å
260	Q	95.2	Very high	93.9	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-53.7	-37.5	-179.3	178.1	69.8	7.8	0	0	112.8	S112 A114 Y115 F134 V258 Q262 V263 Q264 V362	S112-Q260 PolarHBondContact O-NE2 3.16Å; A114-Q260 VanDerWaalsContact CB-OE1 3.29Å; Y115-Q260 HydrophobicContact CE2-CB 4.34Å; F134-Q260 HydrophobicContact CD2-CB 4.49Å; F134-Q260 HydrophobicContact CE1-CB 3.84Å; F134-Q260 HydrophobicContact CE1-CG 4.43Å; F134-Q260 HydrophobicContact CE2-CB 3.8Å; F134-Q260 HydrophobicContact CZ-CB 3.44Å; F134-Q260 VanDerWaalsContact CZ-CB 3.44Å; F134-Q260 HydrophobicContact CZ-CG 4.32Å; V258-Q260 PolarHBondContact O-N 3.25Å; Q260-Q262 VanDerWaalsContact C-N 3.26Å; Q260-Q262 PolarHBondContact O-N 3.34Å; Q260-V263 PolarHBondContact O-N 3.45Å; Q260-Q264 WeakPolarHBondContact O-CB 3.45Å; Q260-Q264 PolarHBondContact O-N 2.87Å; Q260-V362 HydrophobicContact CB-CG1 4.14Å; Q260-V362 HydrophobicContact CG-CG1 3.58Å
261	A	93	Very high	93.8	Very high	2 Å²	2	15 Å²	15	2%	0.017	7%	0.068	C	C	.	.	H	α-helix	trans	-62.1	-32	-178.9	0	0	0	0	0	113.6	M138 N259 R265 S358	M138-A261 HydrophobicContact CE-CB 4.35Å; N259-A261 PolarHBondContact O-N 2.91Å; N259-A261 VanDerWaalsContact O-N 3.13Å; N259-A261 WeakPolarHBondContact OD1-CB 3.37Å; N259-A261 PolarHBondContact OD1-N 3.26Å; A261-R265 PolarHBondContact O-NH1 3.24Å; A261-S358 WeakPolarHBondContact CA-OG 3.39Å; A261-S358 PolarHBondContact N-OG 3.14Å
262	Q	94.3	Very high	93.7	Very high	0 Å²	0	17.2 Å²	17.2	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-85.5	-47.1	173.8	-60.2	-55.5	-70.6	0	0	111.2	L60 F64 L255 Y256 N259 Q260 Q264 R265 Y266	L60-Q262 HydrophobicContact CD2-CB 4.14Å; L60-Q262 HydrophobicContact CD2-CG 4.49Å; L60-Q262 PolarHBondContact O-OE1 2.82Å; F64-Q262 HydrophobicContact CD2-CG 3.88Å; F64-Q262 HydrophobicContact CE2-CG 3.56Å; F64-Q262 VanDerWaalsContact CE2-NE2 3.25Å; L255-Q262 WeakPolarHBondContact O-CG 3.19Å; Y256-Q262 HydrophobicContact CD1-CG 3.95Å; Y256-Q262 HydrophobicContact CE1-CG 4.32Å; N259-Q262 PolarHBondContact O-N 3.03Å; Q260-Q262 VanDerWaalsContact C-N 3.26Å; Q260-Q262 PolarHBondContact O-N 3.34Å; Q262-Q264 VanDerWaalsContact C-N 3.27Å; Q262-Q264 PolarHBondContact O-N 3.46Å; Q262-R265 WeakPolarHBondContact O-CB 3.46Å; Q262-R265 PolarHBondContact O-N 3.12Å; Q262-Y266 HydrophobicContact CB-CE2 3.88Å; Q262-Y266 WeakPolarHBondContact O-CD2 3.44Å; Q262-Y266 PolarHBondContact O-N 3.36Å; Q262-Y266 VanDerWaalsContact O-N 3.11Å
263	V	94.9	Very high	93.7	Very high	3 Å²	3	25.2 Å²	25.2	2%	0.018	11%	0.114	C	C	.	.	H	α-helix	trans	-54.3	-47.2	-179.4	174	0	0	0	0	110.8	L106 A114 N259 Q260 R265 Y266 L267	L106-V263 HydrophobicContact CD1-CG1 3.91Å; L106-V263 HydrophobicContact CD1-CG2 3.95Å; A114-V263 HydrophobicContact CB-CB 4.22Å; A114-V263 HydrophobicContact CB-CG1 3.86Å; A114-V263 HydrophobicContact CB-CG2 4.33Å; N259-V263 WeakPolarHBondContact O-CG2 3.34Å; N259-V263 PolarHBondContact O-N 3.32Å; Q260-V263 PolarHBondContact O-N 3.45Å; V263-R265 VanDerWaalsContact C-N 3.29Å; V263-R265 PolarHBondContact O-N 3.17Å; V263-Y266 WeakPolarHBondContact O-CB 3.32Å; V263-Y266 PolarHBondContact O-N 3.08Å; V263-Y266 VanDerWaalsContact O-N 3.14Å; V263-L267 HydrophobicContact CG1-CD1 3.74Å; V263-L267 HydrophobicContact CG1-CG 4.2Å; V263-L267 VanDerWaalsContact O-CG 3.26Å; V263-L267 WeakPolarHBondContact O-CG 3.48Å; V263-L267 PolarHBondContact O-N 3.12Å
264	Q	92.9	Very high	93.5	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-58.4	-37.6	179.3	-177.6	163.4	14.6	0	0	113.4	L45 M46 L181 Q260 Q262 L267 S268 N357 S358 T361	L45-Q264 PolarHBondContact O-NE2 3.07Å; M46-Q264 HydrophobicContact CE-CG 3.85Å; M46-Q264 HydrophobicContact SD-CG 4.34Å; L181-Q264 HydrophobicContact CD2-CG 4.04Å; Q260-Q264 WeakPolarHBondContact O-CB 3.45Å; Q260-Q264 PolarHBondContact O-N 2.87Å; Q262-Q264 VanDerWaalsContact C-N 3.27Å; Q262-Q264 PolarHBondContact O-N 3.46Å; Q264-L267 PolarHBondContact O-N 3.15Å; Q264-S268 PolarHBondContact O-N 3.34Å; Q264-N357 VanDerWaalsContact CD-OD1 3.32Å; Q264-N357 PolarHBondContact NE2-OD1 3.16Å; Q264-N357 PolarHBondContact OE1-OD1 3.41Å; Q264-S358 VanDerWaalsContact OE1-CA 3.32Å; Q264-S358 PolarHBondContact OE1-OG 2.93Å; Q264-T361 PolarHBondContact NE2-OG1 3.45Å
265	R	93.5	Very high	93.5	Very high	1 Å²	1	26.7 Å²	26.7	0%	0.004	12%	0.12	C	C	.	.	H	α-helix	trans	-68.8	-42.5	175.9	-75.5	173.3	166.8	78.7	4.4	112.2	V56 S59 L60 S63 D188 A261 Q262 V263 L267 S268 S354	V56-R265 HydrophobicContact CG1-CB 4.33Å; S59-R265 PolarHBondContact O-NE 3.27Å; S59-R265 PolarHBondContact OG-NE 3.43Å; S59-R265 PolarHBondContact OG-NH2 3.38Å; L60-R265 HydrophobicContact CD2-CB 3.62Å; L60-R265 HydrophobicContact CD2-CG 4.35Å; L60-R265 HydrophobicContact CG-CB 4.2Å; S63-R265 PolarHBondContact OG-NE 3.42Å; S63-R265 VanDerWaalsContact OG-NE 3.15Å; S63-R265 PolarHBondContact OG-NH1 2.97Å; S63-R265 VanDerWaalsContact OG-NH1 3.13Å; S63-R265 PolarHBondContact OG-NH2 2.95Å; D188-R265 IonicContact OD2-CZ 2.64Å; D188-R265 IonicContact OD2-NE 2.62Å; D188-R265 IonicContact OD2-NH2 3.47Å; D188-R265 PolarHBondContact OD2-NH2 3.06Å; A261-R265 PolarHBondContact O-NH1 3.24Å; Q262-R265 WeakPolarHBondContact O-CB 3.46Å; Q262-R265 PolarHBondContact O-N 3.12Å; V263-R265 VanDerWaalsContact C-N 3.29Å; V263-R265 PolarHBondContact O-N 3.17Å; R265-L267 PolarHBondContact O-N 3.25Å; R265-S268 WeakPolarHBondContact O-CB 3.28Å; R265-S268 PolarHBondContact O-N 3.16Å; R265-S268 VanDerWaalsContact O-N 3.12Å; R265-S268 PolarHBondContact O-OG 3.2Å; R265-S354 VanDerWaalsContact CZ-OG 3.29Å; R265-S354 PolarHBondContact NH1-OG 3.18Å; R265-S354 PolarHBondContact NH2-OG 3.09Å
266	Y	93.4	Very high	93.6	Very high	5 Å²	5	27.1 Å²	27.1	2%	0.02	12%	0.123	C	C	.	.	H	α-helix	trans	-58.7	-41.3	173.5	-58.1	-48.8	0	0	0	111.3	L60 I103 Y107 Y256 Q262 V263 S268 A269 A275 C279	L60-Y266 HydrophobicContact CD1-CD1 3.85Å; L60-Y266 HydrophobicContact CD1-CE1 3.26Å; L60-Y266 HydrophobicContact CD2-CD1 4.05Å; L60-Y266 HydrophobicContact CD2-CE1 3.56Å; L60-Y266 HydrophobicContact CD2-CE2 4.35Å; L60-Y266 HydrophobicContact CG-CE1 4.09Å; I103-Y266 HydrophobicContact CD1-CD1 3.7Å; I103-Y266 HydrophobicContact CD1-CD2 3.73Å; I103-Y266 HydrophobicContact CD1-CE1 3.58Å; I103-Y266 HydrophobicContact CD1-CE2 3.68Å; I103-Y266 HydrophobicContact CD1-CG 3.78Å; I103-Y266 HydrophobicContact CG1-CD1 4.37Å; I103-Y266 HydrophobicContact CG1-CD2 3.63Å; I103-Y266 HydrophobicContact CG1-CE2 3.88Å; I103-Y266 HydrophobicContact CG1-CG 3.94Å; I103-Y266 HydrophobicContact CG2-CG 4.48Å; Y107-Y266 WeakPolarHBondContact CE2-O 3.36Å; Y256-Y266 WeakPolarHBondContact CD1-OH 3.5Å; Y256-Y266 WeakPolarHBondContact O-CE2 3.31Å; Q262-Y266 HydrophobicContact CB-CE2 3.88Å; Q262-Y266 WeakPolarHBondContact O-CD2 3.44Å; Q262-Y266 PolarHBondContact O-N 3.36Å; Q262-Y266 VanDerWaalsContact O-N 3.11Å; V263-Y266 WeakPolarHBondContact O-CB 3.32Å; V263-Y266 PolarHBondContact O-N 3.08Å; V263-Y266 VanDerWaalsContact O-N 3.14Å; Y266-S268 VanDerWaalsContact C-N 3.26Å; Y266-S268 PolarHBondContact O-N 3.24Å; Y266-A269 WeakPolarHBondContact O-CB 3.48Å; Y266-A269 PolarHBondContact O-N 3.38Å; Y266-A275 WeakPolarHBondContact O-CB 3.23Å; Y266-C279 HydrophobicContact CE1-CB 3.92Å
267	L	91.5	Very high	93.6	Very high	4 Å²	4	33 Å²	33	2%	0.021	15%	0.148	C	C	.	.	H	α-helix	trans	-72.2	-17.9	179.2	-61.4	177.9	0	0	0	113.5	M46 R49 Y107 L111 V263 Q264 R265 A269	M46-L267 HydrophobicContact SD-CB 4.44Å; R49-L267 WeakPolarHBondContact CD-O 3.39Å; R49-L267 VanDerWaalsContact CG-O 3.31Å; R49-L267 WeakPolarHBondContact CG-O 3.46Å; Y107-L267 VanDerWaalsContact CA-CD2 3.42Å; Y107-L267 HydrophobicContact CD2-CD2 4.12Å; Y107-L267 HydrophobicContact CG-CD2 4.4Å; L111-L267 WeakPolarHBondContact O-CD1 3.29Å; V263-L267 HydrophobicContact CG1-CD1 3.74Å; V263-L267 HydrophobicContact CG1-CG 4.2Å; V263-L267 VanDerWaalsContact O-CG 3.26Å; V263-L267 WeakPolarHBondContact O-CG 3.48Å; V263-L267 PolarHBondContact O-N 3.12Å; Q264-L267 PolarHBondContact O-N 3.15Å; R265-L267 PolarHBondContact O-N 3.25Å; L267-A269 VanDerWaalsContact C-N 3.32Å
268	S	91.4	Very high	93.7	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	15%	0.148	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.7	-9.8	173	80.1	0	0	0	0	114.1	M46 R49 S50 M51 Q264 R265 Y266	M46-S268 WeakPolarHBondContact O-CB 3.21Å; R49-S268 CarbonylContact C-O 3.56Å; R49-S268 WeakPolarHBondContact CA-O 3.28Å; S50-S268 PolarHBondContact N-O 3.21Å; M51-S268 WeakPolarHBondContact CB-O 3.46Å; M51-S268 PolarHBondContact N-O 3.46Å; Q264-S268 PolarHBondContact O-N 3.34Å; R265-S268 WeakPolarHBondContact O-CB 3.28Å; R265-S268 PolarHBondContact O-N 3.16Å; R265-S268 VanDerWaalsContact O-N 3.12Å; R265-S268 PolarHBondContact O-OG 3.2Å; Y266-S268 VanDerWaalsContact C-N 3.26Å; Y266-S268 PolarHBondContact O-N 3.24Å
269	A	92.8	Very high	93.6	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	15%	0.147	C	C	.	.	B	Isolated β-bridge	trans	-68.4	154.4	175.9	0	0	0	0	0	111.2	M51 Y107 Y266 L267 E274 A275	M51-A269 WeakPolarHBondContact O-CA 3.5Å; Y107-A269 HydrophobicContact CE2-CB 4.39Å; Y107-A269 PolarHBondContact OH-O 3.3Å; Y266-A269 WeakPolarHBondContact O-CB 3.48Å; Y266-A269 PolarHBondContact O-N 3.38Å; L267-A269 VanDerWaalsContact C-N 3.32Å; A269-E274 HydrophobicContact CB-CB 4.35Å; A269-A275 HydrophobicContact CB-CB 3.93Å
270	R	90.7	Very high	93.6	Very high	183 Å²	183	36.9 Å²	36.9	69%	0.691	16%	0.163	S	C	*	.	S	Bend	trans	-70.8	-34.7	-179.4	-169.7	-175.8	178.1	-176.4	0.9	113.5	R49 M51 Y107 E274	R49-R270 VanDerWaalsContact O-CA 3.23Å; R49-R270 WeakPolarHBondContact O-CA 3.29Å; M51-R270 PolarHBondContact O-N 3.4Å; M51-R270 VanDerWaalsContact O-N 3.14Å; Y107-R270 PolarHBondContact OH-O 2.7Å; R270-E274 WeakPolarHBondContact CB-OE2 3.47Å
271	T	93.8	Very high	93.4	Very high	60 Å²	60	39.3 Å²	39.3	37%	0.368	18%	0.175	S	C	.	.	S	Bend	trans	-137	154.9	-178.7	67.8	0	0	0	0	111.4	Y107 K273 E274 A275	Y107-T271 VanDerWaalsContact CZ-C 3.42Å; Y107-T271 WeakPolarHBondContact OH-CA 3.41Å; Y107-T271 PolarHBondContact OH-N 3.17Å; Y107-T271 VanDerWaalsContact OH-N 3.14Å; T271-K273 PolarHBondContact O-N 3.09Å; T271-E274 PolarHBondContact O-N 3.15Å; T271-E274 WeakPolarHBondContact OG1-CG 3.37Å; T271-E274 PolarHBondContact OG1-N 3.44Å; T271-E274 VanDerWaalsContact OG1-N 3.15Å; T271-A275 PolarHBondContact O-N 3.38Å
272	E	93.3	Very high	93.4	Very high	52 Å²	52	39.2 Å²	39.2	24%	0.243	17%	0.174	C	C	.	.	H	α-helix	trans	-55.3	-40	174.1	-176	-177.4	141.8	0	0	111	Y107 R108 E274 A275 V276	Y107-E272 HydrophobicContact CD1-CB 3.7Å; Y107-E272 HydrophobicContact CD1-CG 4.22Å; Y107-E272 HydrophobicContact CE1-CB 3.91Å; Y107-E272 HydrophobicContact CG-CB 4.24Å; Y107-E272 HydrophobicContact CG-CG 4.42Å; R108-E272 WeakPolarHBondContact CG-OE2 3.37Å; R108-E272 IonicContact CZ-OE1 3.58Å; R108-E272 IonicContact CZ-OE2 3.37Å; R108-E272 IonicContact NE-OE1 2.82Å; R108-E272 PolarHBondContact NE-OE1 3.44Å; R108-E272 IonicContact NE-OE2 3.51Å; R108-E272 PolarHBondContact NE-OE2 3.13Å; R108-E272 IonicContact NH2-OE1 3.45Å; R108-E272 PolarHBondContact NH2-OE1 3.33Å; R108-E272 IonicContact NH2-OE2 3.49Å; R108-E272 PolarHBondContact NH2-OE2 3.37Å; E272-E274 PolarHBondContact O-N 3.37Å; E272-A275 WeakPolarHBondContact O-CB 3.39Å; E272-A275 PolarHBondContact O-N 3.07Å; E272-V276 WeakPolarHBondContact O-CG2 3.48Å; E272-V276 PolarHBondContact O-N 3.39Å
273	K	93.4	Very high	93.3	Very high	180 Å²	180	42.6 Å²	42.6	78%	0.783	19%	0.189	S	C	*	.	H	α-helix	trans	-62.6	-41.1	177.3	-67.8	-176.3	179.8	179.7	0	112.1	T271 K277	T271-K273 PolarHBondContact O-N 3.09Å; K273-K277 VanDerWaalsContact O-CB 3.23Å; K273-K277 WeakPolarHBondContact O-CB 3.19Å; K273-K277 PolarHBondContact O-N 3.33Å
274	E	93.6	Very high	93.2	Very high	47 Å²	47	46 Å²	46	22%	0.22	21%	0.211	C	C	.	.	H	α-helix	trans	-69	-37.5	175.4	-76.4	-165.8	120.5	0	0	112.3	C53 A269 R270 T271 E272 K277 S278	C53-E274 HydrophobicContact CB-CB 4.3Å; C53-E274 HydrophobicContact CB-CG 4.24Å; C53-E274 PolarHBondContact N-OE1 3.28Å; A269-E274 HydrophobicContact CB-CB 4.35Å; R270-E274 WeakPolarHBondContact CB-OE2 3.47Å; T271-E274 PolarHBondContact O-N 3.15Å; T271-E274 WeakPolarHBondContact OG1-CG 3.37Å; T271-E274 PolarHBondContact OG1-N 3.44Å; T271-E274 VanDerWaalsContact OG1-N 3.15Å; E272-E274 PolarHBondContact O-N 3.37Å; E274-K277 PolarHBondContact O-N 3.04Å; E274-S278 VanDerWaalsContact O-CB 3.29Å; E274-S278 WeakPolarHBondContact O-CB 3.21Å; E274-S278 PolarHBondContact O-N 3.31Å
275	A	94.1	Very high	93.1	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-59.7	-48.7	173.5	0	0	0	0	0	111.1	I103 Y107 Y266 A269 T271 E272 S278 C279	I103-A275 HydrophobicContact CG2-CB 3.85Å; Y107-A275 HydrophobicContact CD2-CB 3.83Å; Y107-A275 HydrophobicContact CE2-CB 3.97Å; Y266-A275 WeakPolarHBondContact O-CB 3.23Å; A269-A275 HydrophobicContact CB-CB 3.93Å; T271-A275 PolarHBondContact O-N 3.38Å; E272-A275 WeakPolarHBondContact O-CB 3.39Å; E272-A275 PolarHBondContact O-N 3.07Å; A275-S278 PolarHBondContact O-N 3.2Å; A275-S278 PolarHBondContact O-OG 2.8Å; A275-C279 PolarHBondContact O-N 3.13Å
276	V	95.6	Very high	93	Very high	23 Å²	23	47.6 Å²	47.6	14%	0.139	22%	0.222	C	C	.	.	H	α-helix	trans	-64.2	-46.4	177.6	172	0	0	0	0	111.6	A99 I103 P104 E272 S278 C279 Y280	A99-V276 HydrophobicContact CB-CG1 4.27Å; A99-V276 WeakPolarHBondContact O-CG2 3.25Å; I103-V276 HydrophobicContact CG2-CG2 4.05Å; P104-V276 HydrophobicContact CG-CG2 4.28Å; E272-V276 WeakPolarHBondContact O-CG2 3.48Å; E272-V276 PolarHBondContact O-N 3.39Å; V276-S278 VanDerWaalsContact C-N 3.25Å; V276-S278 PolarHBondContact O-N 3.4Å; V276-C279 WeakPolarHBondContact O-CB 3.29Å; V276-C279 PolarHBondContact O-N 2.92Å; V276-C279 VanDerWaalsContact O-N 3.17Å; V276-Y280 HydrophobicContact CG1-CD2 3.93Å; V276-Y280 HydrophobicContact CG1-CE2 3.59Å; V276-Y280 WeakPolarHBondContact O-CD2 2.89Å; V276-Y280 PolarHBondContact O-N 2.78Å; V276-Y280 VanDerWaalsContact O-N 3.15Å
277	K	94.4	Very high	93	Very high	126 Å²	126	49.5 Å²	49.5	55%	0.548	23%	0.231	S	C	.	.	H	α-helix	trans	-61.3	-36	176.8	-172.1	-177.6	176.8	178.1	0	111.4	C53 K273 E274 C279 Y280 M281	C53-K277 VanDerWaalsContact SG-C 3.54Å; C53-K277 VanDerWaalsContact SG-CB 3.55Å; C53-K277 WeakPolarHBondContact SG-CG 3.42Å; K273-K277 VanDerWaalsContact O-CB 3.23Å; K273-K277 WeakPolarHBondContact O-CB 3.19Å; K273-K277 PolarHBondContact O-N 3.33Å; E274-K277 PolarHBondContact O-N 3.04Å; K277-C279 VanDerWaalsContact C-N 3.33Å; K277-C279 PolarHBondContact O-N 3.48Å; K277-Y280 PolarHBondContact O-N 3.45Å; K277-M281 HydrophobicContact CG-SD 4.36Å; K277-M281 WeakPolarHBondContact O-CG 3.23Å; K277-M281 PolarHBondContact O-N 3.49Å
278	S	94.8	Very high	93.1	Very high	0 Å²	0	53.8 Å²	53.8	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-63	-40.5	177	77	0	0	0	0	111.5	C53 V56 S57 E274 A275 V276 Y280 M281 V282	C53-S278 PolarHBondContact SG-N 3.07Å; V56-S278 WeakPolarHBondContact CG1-OG 3.27Å; S57-S278 WeakPolarHBondContact CB-O 3.25Å; E274-S278 VanDerWaalsContact O-CB 3.29Å; E274-S278 WeakPolarHBondContact O-CB 3.21Å; E274-S278 PolarHBondContact O-N 3.31Å; A275-S278 PolarHBondContact O-N 3.2Å; A275-S278 PolarHBondContact O-OG 2.8Å; V276-S278 VanDerWaalsContact C-N 3.25Å; V276-S278 PolarHBondContact O-N 3.4Å; S278-Y280 PolarHBondContact O-N 2.9Å; S278-M281 PolarHBondContact O-N 2.97Å; S278-V282 WeakPolarHBondContact O-CG2 3.39Å; S278-V282 PolarHBondContact O-N 3.49Å
279	C	94.6	Very high	93.2	Very high	0 Å²	0	53.8 Å²	53.8	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-61.6	-42.1	174.1	-171	0	0	0	0	111.8	A99 I103 Y266 A275 V276 K277 M281 V282	A99-C279 HydrophobicContact CB-CB 4.38Å; I103-C279 HydrophobicContact CD1-CB 3.59Å; Y266-C279 HydrophobicContact CE1-CB 3.92Å; A275-C279 PolarHBondContact O-N 3.13Å; V276-C279 WeakPolarHBondContact O-CB 3.29Å; V276-C279 PolarHBondContact O-N 2.92Å; V276-C279 VanDerWaalsContact O-N 3.17Å; K277-C279 VanDerWaalsContact C-N 3.33Å; K277-C279 PolarHBondContact O-N 3.48Å; C279-M281 PolarHBondContact O-N 3.02Å; C279-V282 WeakPolarHBondContact O-CB 3.49Å; C279-V282 PolarHBondContact O-N 2.86Å
280	Y	93.5	Very high	93.3	Very high	89 Å²	89	54.1 Å²	54.1	35%	0.349	26%	0.255	S	S	.	.	H	α-helix	trans	-62.8	-38.7	175	-78.6	-60.2	0	0	0	113.7	L96 A99 H100 V276 K277 S278 V282 F283 P284	L96-Y280 HydrophobicContact CD1-CE1 4.11Å; L96-Y280 WeakPolarHBondContact CD1-OH 3.46Å; A99-Y280 HydrophobicContact CB-CE1 4.42Å; A99-Y280 HydrophobicContact CB-CE2 4.03Å; H100-Y280 PolarHBondContact CD2-OH 3.13Å; H100-Y280 PolarHBondContact CE1-OH 3.33Å; H100-Y280 AromaticContact NE2-CZ 3.96Å; H100-Y280 PolarHBondContact NE2-OH 3.45Å; V276-Y280 HydrophobicContact CG1-CD2 3.93Å; V276-Y280 HydrophobicContact CG1-CE2 3.59Å; V276-Y280 WeakPolarHBondContact O-CD2 2.89Å; V276-Y280 PolarHBondContact O-N 2.78Å; V276-Y280 VanDerWaalsContact O-N 3.15Å; K277-Y280 PolarHBondContact O-N 3.45Å; S278-Y280 PolarHBondContact O-N 2.9Å; Y280-V282 PolarHBondContact O-N 2.89Å; Y280-F283 WeakPolarHBondContact O-CB 3.47Å; Y280-F283 PolarHBondContact O-N 2.93Å; Y280-P284 WeakPolarHBondContact O-CD 3.4Å
281	M	92.5	Very high	93.5	Very high	51 Å²	51	46 Å²	46	25%	0.251	23%	0.228	S	C	.	.	H	α-helix	trans	-70.6	-14.6	178.7	-66.1	-175.5	-25.3	0	0	113.1	C53 L54 S57 K277 S278 C279 P284 S285	C53-M281 HydrophobicContact CB-CE 4.18Å; C53-M281 WeakPolarHBondContact O-CE 3.38Å; C53-M281 WeakPolarHBondContact SG-CE 3.42Å; L54-M281 HydrophobicContact CB-CE 4.37Å; L54-M281 HydrophobicContact CD1-CE 4.41Å; S57-M281 WeakPolarHBondContact OG-CE 3.24Å; K277-M281 HydrophobicContact CG-SD 4.36Å; K277-M281 WeakPolarHBondContact O-CG 3.23Å; K277-M281 PolarHBondContact O-N 3.49Å; S278-M281 PolarHBondContact O-N 2.97Å; C279-M281 PolarHBondContact O-N 3.02Å; M281-P284 WeakPolarHBondContact O-CD 3.44Å; M281-S285 PolarHBondContact O-OG 3.29Å
282	V	92.9	Very high	93.6	Very high	0 Å²	0	44 Å²	44	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-70.1	-35.8	172.6	175.1	0	0	0	0	111.3	L60 I61 L95 Y256 S278 C279 Y280 S285 L286	L60-V282 HydrophobicContact CB-CG2 3.67Å; L60-V282 HydrophobicContact CD1-CG2 3.89Å; L60-V282 HydrophobicContact CG-CG2 4.45Å; I61-V282 HydrophobicContact CG1-CB 4.29Å; I61-V282 HydrophobicContact CG1-CG1 3.97Å; I61-V282 HydrophobicContact CG1-CG2 4.16Å; L95-V282 HydrophobicContact CD1-CB 4.34Å; L95-V282 HydrophobicContact CD1-CG1 4.21Å; L95-V282 HydrophobicContact CD2-CG1 4.31Å; Y256-V282 HydrophobicContact CE1-CG1 3.95Å; S278-V282 WeakPolarHBondContact O-CG2 3.39Å; S278-V282 PolarHBondContact O-N 3.49Å; C279-V282 WeakPolarHBondContact O-CB 3.49Å; C279-V282 PolarHBondContact O-N 2.86Å; Y280-V282 PolarHBondContact O-N 2.89Å; V282-S285 PolarHBondContact O-N 3.35Å; V282-L286 HydrophobicContact CG1-CD1 3.57Å; V282-L286 HydrophobicContact CG1-CG 3.68Å; V282-L286 PolarHBondContact O-N 3.47Å
283	F	91.8	Very high	93.7	Very high	70 Å²	70	41.7 Å²	41.7	31%	0.307	20%	0.204	S	C	.	.	H	α-helix	trans	-54.1	-57.4	-175.8	176.7	-101	0	0	0	114.4	I92 L95 Y280 S285 L286 Q287	I92-F283 HydrophobicContact CB-CE2 4.37Å; I92-F283 HydrophobicContact CG1-CE2 3.55Å; I92-F283 HydrophobicContact CG1-CZ 3.83Å; L95-F283 HydrophobicContact CD1-CB 3.66Å; L95-F283 HydrophobicContact CD1-CD2 4.19Å; L95-F283 HydrophobicContact CD1-CG 4.45Å; Y280-F283 WeakPolarHBondContact O-CB 3.47Å; Y280-F283 PolarHBondContact O-N 2.93Å; F283-S285 PolarHBondContact O-N 2.79Å; F283-L286 PolarHBondContact O-N 2.89Å; F283-Q287 HydrophobicContact CD2-CG 4.4Å; F283-Q287 HydrophobicContact CE1-CG 4.22Å; F283-Q287 HydrophobicContact CE2-CG 3.93Å; F283-Q287 HydrophobicContact CZ-CG 3.84Å; F283-Q287 WeakPolarHBondContact O-CG 3.35Å; F283-Q287 PolarHBondContact O-N 3.22Å
284	P	92.3	Very high	93.7	Very high	74 Å²	74	33.5 Å²	33.5	48%	0.481	17%	0.17	S	C	.	.	H	α-helix	trans	-62	-35	-178.5	24.5	-34.5	0	0	0	112.1	Y280 M281 Q287 L288	Y280-P284 WeakPolarHBondContact O-CD 3.4Å; M281-P284 WeakPolarHBondContact O-CD 3.44Å; P284-Q287 PolarHBondContact O-N 2.82Å; P284-L288 WeakPolarHBondContact O-CB 3.31Å; P284-L288 PolarHBondContact O-N 3Å
285	S	90.6	Very high	93.8	Very high	27 Å²	27	34.5 Å²	34.5	19%	0.189	18%	0.176	C	C	.	.	H	α-helix	trans	-71.3	-38.7	-179.4	-54.7	0	0	0	0	112.7	I61 M281 V282 F283 L288 A289	I61-S285 VanDerWaalsContact CD1-OG 3.3Å; I61-S285 WeakPolarHBondContact CD1-OG 3.48Å; M281-S285 PolarHBondContact O-OG 3.29Å; V282-S285 PolarHBondContact O-N 3.35Å; F283-S285 PolarHBondContact O-N 2.79Å; S285-L288 PolarHBondContact O-N 3.09Å; S285-A289 VanDerWaalsContact O-CB 3.29Å; S285-A289 WeakPolarHBondContact O-CB 3.32Å; S285-A289 PolarHBondContact O-N 2.9Å
286	L	91.9	Very high	93.9	Very high	9 Å²	9	34.6 Å²	34.6	5%	0.047	18%	0.176	C	C	.	.	H	α-helix	trans	-65.7	-39.9	172.6	-77.3	-179	0	0	0	111.8	Y91 L95 Y256 V282 F283 L288 A289 L290	Y91-L286 HydrophobicContact CD2-CB 3.74Å; Y91-L286 HydrophobicContact CD2-CD1 4.28Å; Y91-L286 HydrophobicContact CE2-CB 3.75Å; Y91-L286 HydrophobicContact CE2-CD1 4.48Å; Y91-L286 HydrophobicContact CG-CD1 4.44Å; L95-L286 HydrophobicContact CD1-CD1 4.2Å; Y256-L286 HydrophobicContact CE2-CD1 3.97Å; V282-L286 HydrophobicContact CG1-CD1 3.57Å; V282-L286 HydrophobicContact CG1-CG 3.68Å; V282-L286 PolarHBondContact O-N 3.47Å; F283-L286 PolarHBondContact O-N 2.89Å; L286-L288 VanDerWaalsContact C-N 3.35Å; L286-A289 PolarHBondContact O-N 3.08Å; L286-L290 VanDerWaalsContact O-CB 3.3Å; L286-L290 WeakPolarHBondContact O-CB 3.35Å; L286-L290 PolarHBondContact O-N 2.83Å
287	Q	93.8	Very high	93.8	Very high	45 Å²	45	33.5 Å²	33.5	21%	0.21	17%	0.17	C	C	.	.	H	α-helix	trans	-63.9	-41.8	175	-72.8	-62.5	94.9	0	0	111.6	F283 P284 G291	F283-Q287 HydrophobicContact CD2-CG 4.4Å; F283-Q287 HydrophobicContact CE1-CG 4.22Å; F283-Q287 HydrophobicContact CE2-CG 3.93Å; F283-Q287 HydrophobicContact CZ-CG 3.84Å; F283-Q287 WeakPolarHBondContact O-CG 3.35Å; F283-Q287 PolarHBondContact O-N 3.22Å; P284-Q287 PolarHBondContact O-N 2.82Å; Q287-G291 PolarHBondContact O-N 2.73Å
288	L	94.2	Very high	93.8	Very high	93 Å²	93	28.5 Å²	28.5	49%	0.487	15%	0.149	S	C	.	.	H	α-helix	trans	-62.1	-49.1	174.6	179.8	62.1	0	0	0	111.4	F196 P284 S285 L286 L290 G291 L292	F196-L288 HydrophobicContact CD1-CD2 4.32Å; F196-L288 HydrophobicContact CE1-CB 4.47Å; F196-L288 HydrophobicContact CE1-CD2 3.94Å; F196-L288 HydrophobicContact CE1-CG 3.99Å; F196-L288 HydrophobicContact CZ-CD2 4.43Å; P284-L288 WeakPolarHBondContact O-CB 3.31Å; P284-L288 PolarHBondContact O-N 3Å; S285-L288 PolarHBondContact O-N 3.09Å; L286-L288 VanDerWaalsContact C-N 3.35Å; L288-L290 PolarHBondContact O-N 3.03Å; L288-G291 PolarHBondContact O-N 3.27Å; L288-G291 VanDerWaalsContact O-N 3.11Å; L288-L292 HydrophobicContact CD1-CD1 4.35Å; L288-L292 HydrophobicContact CD1-CG 4.27Å; L288-L292 HydrophobicContact CG-CD1 4.2Å; L288-L292 WeakPolarHBondContact O-CG 3.35Å; L288-L292 PolarHBondContact O-N 3.41Å
289	A	93.4	Very high	93.8	Very high	1 Å²	1	28.5 Å²	28.5	1%	0.008	15%	0.149	C	C	.	.	H	α-helix	trans	-58.2	-44.3	177.5	0	0	0	0	0	113	F196 S285 L286 G291 S293	F196-A289 HydrophobicContact CE1-CB 4.11Å; F196-A289 HydrophobicContact CZ-CB 4.33Å; S285-A289 VanDerWaalsContact O-CB 3.29Å; S285-A289 WeakPolarHBondContact O-CB 3.32Å; S285-A289 PolarHBondContact O-N 2.9Å; L286-A289 PolarHBondContact O-N 3.08Å; A289-G291 VanDerWaalsContact C-N 3.34Å; A289-S293 WeakPolarHBondContact O-CB 3.12Å; A289-S293 PolarHBondContact O-N 2.92Å; A289-S293 VanDerWaalsContact O-N 3.1Å; A289-S293 PolarHBondContact O-OG 3.16Å
290	L	94.4	Very high	93.7	Very high	6 Å²	6	28.5 Å²	28.5	3%	0.031	15%	0.149	C	C	.	.	H	α-helix	trans	-62.8	-42	174.1	-179.8	64.2	0	0	0	110.9	V73 Y84 W85 I87 Y91 L286 L288 S293 C294	V73-L290 HydrophobicContact CG1-CD1 4.23Å; Y84-L290 HydrophobicContact CD1-CD1 3.95Å; Y84-L290 HydrophobicContact CE1-CD1 3.93Å; W85-L290 HydrophobicContact CE3-CD2 3.93Å; W85-L290 HydrophobicContact CE3-CG 3.8Å; W85-L290 HydrophobicContact CZ3-CB 4.33Å; W85-L290 HydrophobicContact CZ3-CD2 4.12Å; W85-L290 HydrophobicContact CZ3-CG 3.88Å; I87-L290 HydrophobicContact CG2-CD1 3.96Å; I87-L290 HydrophobicContact CG2-CD2 3.68Å; I87-L290 HydrophobicContact CG2-CG 4.5Å; Y91-L290 HydrophobicContact CE2-CB 4.36Å; Y91-L290 HydrophobicContact CE2-CD2 4.05Å; L286-L290 VanDerWaalsContact O-CB 3.3Å; L286-L290 WeakPolarHBondContact O-CB 3.35Å; L286-L290 PolarHBondContact O-N 2.83Å; L288-L290 PolarHBondContact O-N 3.03Å; L290-S293 PolarHBondContact O-N 3.1Å; L290-C294 WeakPolarHBondContact O-CB 3.46Å; L290-C294 PolarHBondContact O-N 3.48Å; L290-C294 PolarHBondContact O-SG 2.93Å
291	G	95.1	Very high	93.5	Very high	12 Å²	12	24.4 Å²	24.4	12%	0.124	13%	0.133	C	C	.	.	H	α-helix	trans	-63.7	-48.8	-179.8	0	0	0	0	0	112.5	Q287 L288 A289 S293 C294 I295	Q287-G291 PolarHBondContact O-N 2.73Å; L288-G291 PolarHBondContact O-N 3.27Å; L288-G291 VanDerWaalsContact O-N 3.11Å; A289-G291 VanDerWaalsContact C-N 3.34Å; G291-S293 VanDerWaalsContact C-N 3.29Å; G291-S293 PolarHBondContact O-N 3.09Å; G291-C294 PolarHBondContact O-N 3.08Å; G291-I295 VanDerWaalsContact O-CG1 3.29Å; G291-I295 WeakPolarHBondContact O-CG1 3.46Å; G291-I295 PolarHBondContact O-N 3.49Å
292	L	95.4	Very high	93.5	Very high	20 Å²	20	22 Å²	22	11%	0.105	12%	0.121	C	C	.	.	H	α-helix	trans	-58.2	-43.8	174.8	-66.6	173.8	0	0	0	111.1	F196 I200 I203 L288 C294 I295 M296	F196-L292 HydrophobicContact CD1-CD1 3.66Å; F196-L292 HydrophobicContact CE1-CD1 4.11Å; I200-L292 HydrophobicContact CD1-CD1 4.48Å; I200-L292 HydrophobicContact CG1-CD1 4.03Å; I200-L292 HydrophobicContact CG1-CD2 4.02Å; I203-L292 HydrophobicContact CD1-CB 3.8Å; I203-L292 HydrophobicContact CD1-CD2 3.75Å; I203-L292 HydrophobicContact CD1-CG 4.37Å; I203-L292 VanDerWaalsContact CD1-O 3.24Å; I203-L292 WeakPolarHBondContact CD1-O 3.41Å; L288-L292 HydrophobicContact CD1-CD1 4.35Å; L288-L292 HydrophobicContact CD1-CG 4.27Å; L288-L292 HydrophobicContact CG-CD1 4.2Å; L288-L292 WeakPolarHBondContact O-CG 3.35Å; L288-L292 PolarHBondContact O-N 3.41Å; L292-C294 PolarHBondContact O-N 2.8Å; L292-I295 PolarHBondContact O-N 3.2Å; L292-M296 WeakPolarHBondContact O-CB 3.36Å; L292-M296 PolarHBondContact O-N 3.13Å
293	S	94.9	Very high	93.3	Very high	2 Å²	2	25.3 Å²	25.3	1%	0.014	13%	0.134	C	C	.	.	H	α-helix	trans	-65.4	-37.8	178.7	-54.8	0	0	0	0	112.6	Q199 A289 L290 G291 G297	Q199-S293 PolarHBondContact NE2-OG 3.42Å; A289-S293 WeakPolarHBondContact O-CB 3.12Å; A289-S293 PolarHBondContact O-N 2.92Å; A289-S293 VanDerWaalsContact O-N 3.1Å; A289-S293 PolarHBondContact O-OG 3.16Å; L290-S293 PolarHBondContact O-N 3.1Å; G291-S293 VanDerWaalsContact C-N 3.29Å; G291-S293 PolarHBondContact O-N 3.09Å; S293-G297 PolarHBondContact O-N 3.5Å
294	C	94.7	Very high	93.1	Very high	9 Å²	9	22 Å²	22	6%	0.061	12%	0.119	C	C	.	.	H	α-helix	trans	-67.3	-45.8	175	-68.3	0	0	0	0	111.9	I77 W85 L290 G291 L292 M296 G297 L298	I77-C294 HydrophobicContact CD1-CB 4.43Å; W85-C294 HydrophobicContact CE3-CB 4.28Å; L290-C294 WeakPolarHBondContact O-CB 3.46Å; L290-C294 PolarHBondContact O-N 3.48Å; L290-C294 PolarHBondContact O-SG 2.93Å; G291-C294 PolarHBondContact O-N 3.08Å; L292-C294 PolarHBondContact O-N 2.8Å; C294-M296 VanDerWaalsContact C-N 3.3Å; C294-M296 PolarHBondContact O-N 3.49Å; C294-G297 PolarHBondContact O-N 2.97Å; C294-L298 WeakPolarHBondContact O-CG 3.22Å; C294-L298 PolarHBondContact O-N 2.76Å
295	I	95.5	Very high	92.6	Very high	68 Å²	68	19 Å²	19	35%	0.349	10%	0.1	S	C	.	.	H	α-helix	trans	-59.4	-45.1	175.9	-67	165	0	0	0	109.8	I203 G291 L292 G297 L298 V299	I203-I295 HydrophobicContact CG2-CG2 3.62Å; G291-I295 VanDerWaalsContact O-CG1 3.29Å; G291-I295 WeakPolarHBondContact O-CG1 3.46Å; G291-I295 PolarHBondContact O-N 3.49Å; L292-I295 PolarHBondContact O-N 3.2Å; I295-G297 PolarHBondContact O-N 2.94Å; I295-L298 PolarHBondContact O-N 3.49Å; I295-L298 VanDerWaalsContact O-N 3.16Å; I295-V299 HydrophobicContact CG2-CG2 4.17Å; I295-V299 VanDerWaalsContact O-CG2 3.27Å; I295-V299 WeakPolarHBondContact O-CG2 3.42Å; I295-V299 PolarHBondContact O-N 2.98Å
296	M	95.2	Very high	91.7	Very high	1 Å²	1	20.4 Å²	20.4	1%	0.005	12%	0.119	C	C	.	.	H	α-helix	trans	-57.9	-46.5	177.4	-169.7	158.7	74.4	0	0	111.9	I70 P74 V202 I203 L292 C294 L298 V299 M300 V322 F325	I70-M296 WeakPolarHBondContact O-CE 3.17Å; P74-M296 HydrophobicContact CB-CB 4.32Å; P74-M296 HydrophobicContact CB-CE 3.87Å; P74-M296 HydrophobicContact CB-CG 4.3Å; P74-M296 HydrophobicContact CG-CB 4.32Å; P74-M296 HydrophobicContact CG-CE 3.18Å; P74-M296 HydrophobicContact CG-CG 4.44Å; V202-M296 HydrophobicContact CB-SD 4.19Å; V202-M296 HydrophobicContact CG1-CG 4.31Å; V202-M296 HydrophobicContact CG1-SD 3.59Å; V202-M296 VanDerWaalsContact CG1-SD 3.59Å; I203-M296 HydrophobicContact CD1-CB 4.32Å; I203-M296 HydrophobicContact CG1-CB 3.94Å; I203-M296 HydrophobicContact CG1-CG 4.41Å; L292-M296 WeakPolarHBondContact O-CB 3.36Å; L292-M296 PolarHBondContact O-N 3.13Å; C294-M296 VanDerWaalsContact C-N 3.3Å; C294-M296 PolarHBondContact O-N 3.49Å; M296-L298 VanDerWaalsContact C-N 3.33Å; M296-L298 PolarHBondContact O-N 3.17Å; M296-V299 PolarHBondContact O-N 2.83Å; M296-M300 WeakPolarHBondContact O-CB 3.35Å; M296-M300 VanDerWaalsContact O-CG 3.24Å; M296-M300 WeakPolarHBondContact O-CG 3.32Å; M296-M300 PolarHBondContact O-N 3.02Å; M296-V322 HydrophobicContact CE-CG1 4.29Å; M296-F325 HydrophobicContact CG-CE1 4.1Å
297	G	93.8	Very high	90.8	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-64.1	-33.7	176.4	0	0	0	0	0	114.1	P74 S293 C294 I295 M300 F301	P74-G297 WeakPolarHBondContact O-CA 3.29Å; S293-G297 PolarHBondContact O-N 3.5Å; C294-G297 PolarHBondContact O-N 2.97Å; I295-G297 PolarHBondContact O-N 2.94Å; G297-M300 WeakPolarHBondContact O-CB 3.23Å; G297-F301 PolarHBondContact O-N 2.77Å
298	L	94	Very high	89.3	Confident	21 Å²	21	27.5 Å²	27.5	11%	0.11	16%	0.156	C	C	.	.	H	α-helix	trans	-70.4	-41.3	174.6	-72.7	179.6	0	0	0	112.6	I77 T82 V220 R225 L226 C294 I295 M296 M300 F301 A302	I77-L298 HydrophobicContact CG2-CD2 4.17Å; I77-L298 HydrophobicContact CG2-CG 4.13Å; T82-L298 HydrophobicContact CG2-CD1 3.99Å; T82-L298 HydrophobicContact CG2-CD2 3.68Å; T82-L298 HydrophobicContact CG2-CG 4.1Å; V220-L298 HydrophobicContact CG1-CD1 4.46Å; V220-L298 HydrophobicContact CG1-CD2 3.78Å; V220-L298 HydrophobicContact CG2-CB 4.06Å; V220-L298 HydrophobicContact CG2-CD2 4.02Å; R225-L298 HydrophobicContact CB-CD2 4.17Å; L226-L298 HydrophobicContact CD2-CD1 4.36Å; C294-L298 WeakPolarHBondContact O-CG 3.22Å; C294-L298 PolarHBondContact O-N 2.76Å; I295-L298 PolarHBondContact O-N 3.49Å; I295-L298 VanDerWaalsContact O-N 3.16Å; M296-L298 VanDerWaalsContact C-N 3.33Å; M296-L298 PolarHBondContact O-N 3.17Å; L298-M300 VanDerWaalsContact C-N 3.35Å; L298-F301 WeakPolarHBondContact O-CB 3.43Å; L298-F301 PolarHBondContact O-N 2.87Å; L298-A302 PolarHBondContact O-N 3.4Å
299	V	95	Very high	87.8	Confident	1 Å²	1	24 Å²	24	1%	0.006	14%	0.137	C	C	.	.	H	α-helix	trans	-64.5	-43.1	175.1	176.7	0	0	0	0	110.1	G206 V207 V216 I295 M296 F301 A302 R303 F325	G206-V299 VanDerWaalsContact C-CG1 3.46Å; V207-V299 HydrophobicContact CG2-CG1 4.49Å; V207-V299 HydrophobicContact CG2-CG2 3.59Å; V216-V299 HydrophobicContact CG1-CG2 4.07Å; I295-V299 HydrophobicContact CG2-CG2 4.17Å; I295-V299 VanDerWaalsContact O-CG2 3.27Å; I295-V299 WeakPolarHBondContact O-CG2 3.42Å; I295-V299 PolarHBondContact O-N 2.98Å; M296-V299 PolarHBondContact O-N 2.83Å; V299-F301 VanDerWaalsContact C-N 3.27Å; V299-F301 PolarHBondContact O-N 2.68Å; V299-A302 PolarHBondContact O-N 3.29Å; V299-R303 WeakPolarHBondContact O-CB 3.29Å; V299-R303 PolarHBondContact O-N 2.85Å; V299-F325 HydrophobicContact CB-CZ 4.35Å; V299-F325 HydrophobicContact CG1-CE2 4.17Å; V299-F325 HydrophobicContact CG1-CZ 3.75Å
300	M	92.4	Very high	85.9	Confident	0 Å²	0	26.5 Å²	26.5	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-54	-45.5	171.6	-75.8	177.1	64.7	0	0	111.8	P74 Y78 M296 G297 L298 R303 Y304 M321 V322 F325	P74-M300 HydrophobicContact CB-SD 4.01Å; Y78-M300 HydrophobicContact CD2-CB 3.94Å; Y78-M300 HydrophobicContact CG-CB 4.45Å; Y78-M300 HydrophobicContact CG-CE 4.31Å; M296-M300 WeakPolarHBondContact O-CB 3.35Å; M296-M300 VanDerWaalsContact O-CG 3.24Å; M296-M300 WeakPolarHBondContact O-CG 3.32Å; M296-M300 PolarHBondContact O-N 3.02Å; G297-M300 WeakPolarHBondContact O-CB 3.23Å; L298-M300 VanDerWaalsContact C-N 3.35Å; M300-R303 PolarHBondContact O-N 3.3Å; M300-Y304 WeakPolarHBondContact O-CD2 3.45Å; M300-Y304 PolarHBondContact O-N 2.97Å; M300-Y304 VanDerWaalsContact O-N 3.16Å; M300-M321 HydrophobicContact CE-CB 4.32Å; M300-M321 HydrophobicContact CE-CG 4.04Å; M300-V322 HydrophobicContact CE-CB 4.14Å; M300-V322 HydrophobicContact CE-CG2 3.62Å; M300-V322 HydrophobicContact SD-CB 4.3Å; M300-V322 HydrophobicContact SD-CG1 4.29Å; M300-V322 HydrophobicContact SD-CG2 3.85Å; M300-F325 HydrophobicContact CB-CD2 4.41Å; M300-F325 HydrophobicContact CB-CG 4.44Å; M300-F325 HydrophobicContact CE-CB 4.09Å; M300-F325 HydrophobicContact CG-CB 3.9Å; M300-F325 HydrophobicContact CG-CD1 3.33Å; M300-F325 HydrophobicContact CG-CD2 3.72Å; M300-F325 HydrophobicContact CG-CE1 3.63Å; M300-F325 HydrophobicContact CG-CE2 3.97Å; M300-F325 HydrophobicContact CG-CG 3.36Å; M300-F325 HydrophobicContact CG-CZ 3.94Å; M300-F325 HydrophobicContact SD-CB 4.32Å; M300-F325 HydrophobicContact SD-CD1 3.99Å; M300-F325 HydrophobicContact SD-CG 4.24Å
301	F	90.3	Very high	83.7	Confident	2 Å²	2	35.4 Å²	35.4	1%	0.009	20%	0.196	C	C	.	.	H	α-helix	trans	-63.7	-48.6	177.1	173.2	-97.3	0	0	0	111.7	Y78 V220 R225 G297 L298 V299 R303 Y304 C305	Y78-F301 HydrophobicContact CD2-CB 4.01Å; V220-F301 HydrophobicContact CG2-CD1 4.17Å; R225-F301 HydrophobicContact CB-CD1 4.36Å; R225-F301 HydrophobicContact CB-CE1 4.46Å; R225-F301 HydrophobicContact CG-CD1 3.48Å; R225-F301 VanDerWaalsContact CG-CD1 3.48Å; R225-F301 HydrophobicContact CG-CD2 3.84Å; R225-F301 HydrophobicContact CG-CE1 3.42Å; R225-F301 VanDerWaalsContact CG-CE1 3.42Å; R225-F301 HydrophobicContact CG-CE2 3.82Å; R225-F301 HydrophobicContact CG-CG 3.67Å; R225-F301 HydrophobicContact CG-CZ 3.59Å; G297-F301 PolarHBondContact O-N 2.77Å; L298-F301 WeakPolarHBondContact O-CB 3.43Å; L298-F301 PolarHBondContact O-N 2.87Å; V299-F301 VanDerWaalsContact C-N 3.27Å; V299-F301 PolarHBondContact O-N 2.68Å; F301-R303 PolarHBondContact O-N 3.48Å; F301-Y304 PolarHBondContact O-N 2.77Å; F301-C305 HydrophobicContact CD2-CB 4.39Å; F301-C305 HydrophobicContact CE1-CB 4.07Å; F301-C305 HydrophobicContact CE2-CB 3.87Å; F301-C305 HydrophobicContact CZ-CB 3.72Å; F301-C305 VanDerWaalsContact O-CB 3.3Å; F301-C305 WeakPolarHBondContact O-CB 3.3Å; F301-C305 PolarHBondContact O-N 3.07Å
302	A	91.3	Very high	81.6	Confident	0 Å²	0	42.6 Å²	42.6	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-60.9	-30.4	179.8	0	0	0	0	0	113	T210 V216 K219 V220 L298 V299	T210-A302 HydrophobicContact CG2-CB 3.87Å; V216-A302 HydrophobicContact CB-CB 4.16Å; V216-A302 HydrophobicContact CG1-CB 3.92Å; V216-A302 HydrophobicContact CG2-CB 4.11Å; K219-A302 HydrophobicContact CB-CB 4.09Å; K219-A302 HydrophobicContact CD-CB 4.16Å; K219-A302 WeakPolarHBondContact CD-O 3.39Å; K219-A302 PolarHBondContact NZ-O 3.18Å; V220-A302 HydrophobicContact CG2-CB 4.39Å; L298-A302 PolarHBondContact O-N 3.4Å; V299-A302 PolarHBondContact O-N 3.29Å
303	R	89.8	Confident	79.6	Confident	70 Å²	70	43 Å²	43	26%	0.264	23%	0.226	S	C	.	.	H	α-helix	trans	-74.3	-41	177.5	177.9	57.3	-171.1	84.6	4.5	112.8	T210 V299 M300 F301 E307 F325 D328 M329	T210-R303 HydrophobicContact CG2-CB 4.28Å; V299-R303 WeakPolarHBondContact O-CB 3.29Å; V299-R303 PolarHBondContact O-N 2.85Å; M300-R303 PolarHBondContact O-N 3.3Å; F301-R303 PolarHBondContact O-N 3.48Å; R303-E307 IonicContact NH1-OE1 3.23Å; R303-E307 PolarHBondContact NH1-OE1 3.36Å; R303-F325 HydrophobicContact CB-CE2 4.4Å; R303-D328 IonicContact NE-OD2 3.96Å; R303-D328 IonicContact NH2-OD2 3.62Å; R303-M329 HydrophobicContact CG-CE 3.85Å; R303-M329 HydrophobicContact CG-SD 4.37Å
304	Y	86.8	Confident	77.5	Confident	0 Å²	0	45.1 Å²	45.1	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-112	6.8	-171.3	-58.4	-60.2	0	0	0	114.8	M300 F301 G306 E307 F309 M321 Y324 F325 D328	M300-Y304 WeakPolarHBondContact O-CD2 3.45Å; M300-Y304 PolarHBondContact O-N 2.97Å; M300-Y304 VanDerWaalsContact O-N 3.16Å; F301-Y304 PolarHBondContact O-N 2.77Å; Y304-G306 PolarHBondContact O-N 3.15Å; Y304-E307 PolarHBondContact O-N 2.84Å; Y304-E307 VanDerWaalsContact O-N 3.15Å; Y304-F309 AromaticContact CD1-CE2 3.63Å; Y304-F309 HydrophobicContact CD1-CE2 3.63Å; Y304-F309 HydrophobicContact CD1-CZ 4.05Å; Y304-F309 HydrophobicContact CE1-CE2 4.32Å; Y304-F309 HydrophobicContact CE1-CZ 4.29Å; Y304-F309 HydrophobicContact CG-CE2 4.1Å; Y304-M321 HydrophobicContact CD1-CE 4.26Å; Y304-M321 HydrophobicContact CD2-CE 3.39Å; Y304-M321 HydrophobicContact CE1-CE 4.41Å; Y304-M321 HydrophobicContact CE2-CE 3.53Å; Y304-M321 HydrophobicContact CG-CE 3.78Å; Y304-Y324 HydrophobicContact CE1-CD1 4.49Å; Y304-Y324 AromaticContact CE1-CE1 3.8Å; Y304-Y324 HydrophobicContact CE1-CE1 3.8Å; Y304-Y324 HydrophobicContact CE2-CD1 4.36Å; Y304-Y324 HydrophobicContact CE2-CE1 4.45Å; Y304-Y324 AromaticContact CZ-CD1 3.93Å; Y304-Y324 AromaticContact CZ-CE1 3.64Å; Y304-Y324 WeakPolarHBondContact OH-CE1 3.29Å; Y304-F325 HydrophobicContact CE2-CB 3.92Å; Y304-F325 AromaticContact CE2-CD2 3.66Å; Y304-F325 HydrophobicContact CE2-CD2 3.66Å; Y304-F325 HydrophobicContact CE2-CG 4.26Å; Y304-D328 VanDerWaalsContact OH-CB 3.29Å; Y304-D328 WeakPolarHBondContact OH-CB 3.3Å; Y304-D328 PolarHBondContact OH-OD2 2.89Å
305	C	83.2	Confident	75	Confident	11 Å²	11	49.6 Å²	49.6	7%	0.074	28%	0.279	C	S	.	.	T	Hydrogen-bonded Turn	trans	-59.3	138.2	170.7	76.6	0	0	0	0	109.3	F301 E307 C475	F301-C305 HydrophobicContact CD2-CB 4.39Å; F301-C305 HydrophobicContact CE1-CB 4.07Å; F301-C305 HydrophobicContact CE2-CB 3.87Å; F301-C305 HydrophobicContact CZ-CB 3.72Å; F301-C305 VanDerWaalsContact O-CB 3.3Å; F301-C305 WeakPolarHBondContact O-CB 3.3Å; F301-C305 PolarHBondContact O-N 3.07Å; C305-E307 VanDerWaalsContact C-N 3.31Å; C305-C475 HydrophobicContact CB-CB 3.98Å; C305-C475 WeakPolarHBondContact CB-SG 3.27Å; C305-C475 PolarHBondContact O-SG 2.95Å; C305-C475 WeakPolarHBondContact SG-CB 3.47Å; C305-C475 CovalentContact SG-SG 2.04Å; C305-C475 PolarHBondContact SG-SG 3.39Å
306	G	70.9	Confident	72.9	Confident	58 Å²	58	49.4 Å²	49.4	60%	0.598	28%	0.284	S	S	*	.	T	Hydrogen-bonded Turn	trans	86.8	-12	-175.6	0	0	0	0	0	114.8	Y304 P473	Y304-G306 PolarHBondContact O-N 3.15Å; G306-P473 WeakPolarHBondContact CA-O 3.24Å; G306-P473 PolarHBondContact N-O 3.26Å
307	E	72.6	Confident	71.2	Confident	80 Å²	80	50 Å²	50	37%	0.374	29%	0.288	S	S	.	.			trans	-101.5	121.1	179.5	-63.7	-176	-149.6	0	0	110.9	R303 Y304 C305 F309	R303-E307 IonicContact NH1-OE1 3.23Å; R303-E307 PolarHBondContact NH1-OE1 3.36Å; Y304-E307 PolarHBondContact O-N 2.84Å; Y304-E307 VanDerWaalsContact O-N 3.15Å; C305-E307 VanDerWaalsContact C-N 3.31Å; E307-F309 HydrophobicContact CB-CD2 3.86Å; E307-F309 HydrophobicContact CB-CE2 3.54Å; E307-F309 HydrophobicContact CG-CE2 4.37Å; E307-F309 PolarHBondContact O-N 3.17Å; E307-F309 VanDerWaalsContact O-N 3.16Å; E307-F309 WeakPolarHBondContact OE2-CE2 3.29Å; E307-F309 VanDerWaalsContact OE2-CZ 3.26Å; E307-F309 WeakPolarHBondContact OE2-CZ 3.38Å
308	D	61.6	Low	70.2	Confident	122 Å²	122	52.7 Å²	52.7	65%	0.652	30%	0.298	S	S	*	.			trans	-85.9	89.7	-179.5	-128.7	-21.2	0	0	0	111.2	S310	D308-S310 VanDerWaalsContact C-N 3.27Å; D308-S310 PolarHBondContact O-N 3.18Å
309	F	63.9	Low	69.5	Low	19 Å²	19	52.3 Å²	52.3	8%	0.083	30%	0.296	C	S	.	.	T	Hydrogen-bonded Turn	trans	-81.9	-2.8	177.5	-80.9	-86.1	0	0	0	113.8	Y304 E307 E311 K312 L313 M321 Y324	Y304-F309 AromaticContact CD1-CE2 3.63Å; Y304-F309 HydrophobicContact CD1-CE2 3.63Å; Y304-F309 HydrophobicContact CD1-CZ 4.05Å; Y304-F309 HydrophobicContact CE1-CE2 4.32Å; Y304-F309 HydrophobicContact CE1-CZ 4.29Å; Y304-F309 HydrophobicContact CG-CE2 4.1Å; E307-F309 HydrophobicContact CB-CD2 3.86Å; E307-F309 HydrophobicContact CB-CE2 3.54Å; E307-F309 HydrophobicContact CG-CE2 4.37Å; E307-F309 PolarHBondContact O-N 3.17Å; E307-F309 VanDerWaalsContact O-N 3.16Å; E307-F309 WeakPolarHBondContact OE2-CE2 3.29Å; E307-F309 VanDerWaalsContact OE2-CZ 3.26Å; E307-F309 WeakPolarHBondContact OE2-CZ 3.38Å; F309-E311 VanDerWaalsContact C-N 3.27Å; F309-E311 PolarHBondContact O-N 3.13Å; F309-K312 HydrophobicContact CD1-CB 4.48Å; F309-K312 HydrophobicContact CD1-CD 4.36Å; F309-K312 HydrophobicContact CE1-CD 4.47Å; F309-K312 PolarHBondContact O-N 2.66Å; F309-K312 VanDerWaalsContact O-N 3.15Å; F309-L313 PolarHBondContact O-N 3.16Å; F309-M321 HydrophobicContact CB-SD 4.28Å; F309-M321 HydrophobicContact CD1-CE 4.38Å; F309-M321 HydrophobicContact CD2-CE 4.04Å; F309-M321 HydrophobicContact CE2-CE 4.19Å; F309-M321 HydrophobicContact CG-CE 4.13Å; F309-M321 HydrophobicContact CG-SD 4.26Å; F309-M321 HydrophobicContact CZ-CE 4.46Å; F309-Y324 AromaticContact CE1-CE1 3.98Å; F309-Y324 HydrophobicContact CE1-CE1 3.98Å; F309-Y324 HydrophobicContact CZ-CE1 4.01Å
310	S	53.3	Low	68.9	Low	55 Å²	55	53.2 Å²	53.2	39%	0.385	30%	0.304	S	S	.	.	H	α-helix	trans	-64.9	-28.6	-174.1	-162.2	0	0	0	0	113.1	D308 R470	D308-S310 VanDerWaalsContact C-N 3.27Å; D308-S310 PolarHBondContact O-N 3.18Å; S310-R470 PolarHBondContact OG-NH1 3.21Å; S310-R470 VanDerWaalsContact OG-NH1 3.09Å
311	E	48.1	Very low	68.5	Low	192 Å²	192	53.5 Å²	53.5	90%	0.897	31%	0.305	S	S	*	.	H	α-helix	trans	-81.6	-29.6	174.9	-68.7	-170.7	160.4	0	0	113.2	F309	F309-E311 VanDerWaalsContact C-N 3.27Å; F309-E311 PolarHBondContact O-N 3.13Å
312	K	51.3	Low	68.5	Low	164 Å²	164	53.4 Å²	53.4	71%	0.713	31%	0.305	S	S	*	.	H	α-helix	trans	-80.8	-23.4	-176.3	-75.6	-178.9	-179.6	173	0	114.4	F309	F309-K312 HydrophobicContact CD1-CB 4.48Å; F309-K312 HydrophobicContact CD1-CD 4.36Å; F309-K312 HydrophobicContact CE1-CD 4.47Å; F309-K312 PolarHBondContact O-N 2.66Å; F309-K312 VanDerWaalsContact O-N 3.15Å
313	L	53.1	Low	68.3	Low	29 Å²	29	53.5 Å²	53.5	15%	0.152	31%	0.306	C	S	.	.	H	α-helix	trans	-119.3	-4.1	-165.2	-116.1	77	0	0	0	116	M1 F309 S317 A320 M321	M1-L313 HydrophobicContact CE-CD1 4.44Å; F309-L313 PolarHBondContact O-N 3.16Å; L313-S317 WeakPolarHBondContact CD2-O 3.5Å; L313-A320 HydrophobicContact CD2-CB 4Å; L313-M321 HydrophobicContact CD2-CB 4.25Å; L313-M321 HydrophobicContact CD2-SD 3.91Å
314	G	51.9	Low	68.2	Low	46 Å²	46	53.6 Å²	53.6	47%	0.474	31%	0.306	S	S	.	.			trans	65.5	-160.2	174.7	0	0	0	0	0	115.7	S317	G314-S317 WeakPolarHBondContact O-CB 3.38Å; G314-S317 PolarHBondContact O-OG 3.42Å
315	S	41.3	Very low	68.4	Low	102 Å²	102	53.7 Å²	53.7	71%	0.713	31%	0.307	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.6	-24.3	179.7	53.3	0	0	0	0	114.1	S317	S315-S317 PolarHBondContact O-N 3.15Å; S315-S317 VanDerWaalsContact O-N 3.15Å
316	S	50.8	Low	68.7	Low	64 Å²	64	53.1 Å²	53.1	45%	0.448	30%	0.303	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.2	13.6	172.1	-142	0	0	0	0	113.2	R318	S316-R318 PolarHBondContact O-N 3.01Å
317	S	60.8	Low	69.6	Low	14 Å²	14	51.2 Å²	51.2	10%	0.098	28%	0.279	C	S	.	.	H	α-helix	trans	-71.2	-28.4	-164.1	43.5	0	0	0	0	116.1	L313 G314 S315 M321	L313-S317 WeakPolarHBondContact CD2-O 3.5Å; G314-S317 WeakPolarHBondContact O-CB 3.38Å; G314-S317 PolarHBondContact O-OG 3.42Å; S315-S317 PolarHBondContact O-N 3.15Å; S315-S317 VanDerWaalsContact O-N 3.15Å; S317-M321 WeakPolarHBondContact O-CB 3.32Å; S317-M321 PolarHBondContact O-N 3.48Å
318	R	72.9	Confident	70.3	Confident	57 Å²	57	48.5 Å²	48.5	22%	0.215	27%	0.267	C	S	.	.	H	α-helix	trans	-70.3	-53.8	-167.8	-68.8	-179.7	-74.7	176.4	-7.8	112.2	A75 T79 S316 A320 M321 D407 S408	A75-R318 WeakPolarHBondContact CB-O 3.3Å; T79-R318 HydrophobicContact CG2-CG 4.27Å; S316-R318 PolarHBondContact O-N 3.01Å; R318-A320 VanDerWaalsContact C-N 3.34Å; R318-M321 WeakPolarHBondContact O-CB 3.49Å; R318-M321 PolarHBondContact O-N 3.47Å; R318-D407 IonicContact NH2-OD1 3.56Å; R318-S408 VanDerWaalsContact NH2-N 3.16Å
319	D	78.9	Confident	71.7	Confident	13 Å²	13	42.9 Å²	42.9	7%	0.07	24%	0.237	C	C	.	.	H	α-helix	trans	-73.7	-32.7	-178.2	-56.6	-26.2	0	0	0	110.3	I71 F151 M321 V322 S408 V409	I71-D319 HydrophobicContact CG2-CB 3.71Å; F151-D319 HydrophobicContact CE1-CB 4.06Å; D319-M321 VanDerWaalsContact C-N 3.29Å; D319-M321 PolarHBondContact O-N 2.85Å; D319-V322 PolarHBondContact O-N 3.28Å; D319-S408 PolarHBondContact OD1-OG 3.28Å; D319-S408 VanDerWaalsContact OD2-CA 3.29Å; D319-S408 WeakPolarHBondContact OD2-CA 3.38Å; D319-V409 WeakPolarHBondContact OD2-CG2 3.34Å; D319-V409 PolarHBondContact OD2-N 2.93Å
320	A	81.5	Confident	73	Confident	20 Å²	20	42 Å²	42	17%	0.165	23%	0.233	C	C	.	.	H	α-helix	trans	-61.4	-33.9	173.2	0	0	0	0	0	113	F151 L313 R318 V322 I323 Y324	F151-A320 HydrophobicContact CZ-CB 3.96Å; L313-A320 HydrophobicContact CD2-CB 4Å; R318-A320 VanDerWaalsContact C-N 3.34Å; A320-V322 VanDerWaalsContact C-N 3.26Å; A320-V322 PolarHBondContact O-N 2.75Å; A320-I323 PolarHBondContact O-N 2.84Å; A320-I323 VanDerWaalsContact O-N 3.17Å; A320-Y324 PolarHBondContact O-N 3.34Å
321	M	84.4	Confident	74.5	Confident	5 Å²	5	44.3 Å²	44.3	3%	0.025	24%	0.237	C	C	.	.	H	α-helix	trans	-62.2	-35	-178.9	-165.2	70.7	-148.6	0	0	112.2	Y78 M300 Y304 F309 L313 S317 R318 D319 Y324 F325	Y78-M321 HydrophobicContact CD1-CG 4.27Å; Y78-M321 HydrophobicContact CE1-CG 3.83Å; M300-M321 HydrophobicContact CE-CB 4.32Å; M300-M321 HydrophobicContact CE-CG 4.04Å; Y304-M321 HydrophobicContact CD1-CE 4.26Å; Y304-M321 HydrophobicContact CD2-CE 3.39Å; Y304-M321 HydrophobicContact CE1-CE 4.41Å; Y304-M321 HydrophobicContact CE2-CE 3.53Å; Y304-M321 HydrophobicContact CG-CE 3.78Å; F309-M321 HydrophobicContact CB-SD 4.28Å; F309-M321 HydrophobicContact CD1-CE 4.38Å; F309-M321 HydrophobicContact CD2-CE 4.04Å; F309-M321 HydrophobicContact CE2-CE 4.19Å; F309-M321 HydrophobicContact CG-CE 4.13Å; F309-M321 HydrophobicContact CG-SD 4.26Å; F309-M321 HydrophobicContact CZ-CE 4.46Å; L313-M321 HydrophobicContact CD2-CB 4.25Å; L313-M321 HydrophobicContact CD2-SD 3.91Å; S317-M321 WeakPolarHBondContact O-CB 3.32Å; S317-M321 PolarHBondContact O-N 3.48Å; R318-M321 WeakPolarHBondContact O-CB 3.49Å; R318-M321 PolarHBondContact O-N 3.47Å; D319-M321 VanDerWaalsContact C-N 3.29Å; D319-M321 PolarHBondContact O-N 2.85Å; M321-Y324 HydrophobicContact CE-CD1 3.63Å; M321-Y324 HydrophobicContact CE-CE1 4.1Å; M321-Y324 PolarHBondContact O-N 3.33Å; M321-F325 WeakPolarHBondContact O-CB 3.37Å; M321-F325 PolarHBondContact O-N 3.46Å
322	V	89.4	Confident	76.2	Confident	0 Å²	0	38.5 Å²	38.5	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-67.1	-42.3	176.9	-178.3	0	0	0	0	110.3	I71 P74 A75 M296 M300 D319 A320 F325 V326	I71-V322 HydrophobicContact CG2-CB 4.24Å; I71-V322 HydrophobicContact CG2-CG2 4.38Å; I71-V322 WeakPolarHBondContact O-CG2 3.48Å; P74-V322 HydrophobicContact CB-CG2 4.22Å; A75-V322 HydrophobicContact CB-CG2 3.75Å; M296-V322 HydrophobicContact CE-CG1 4.29Å; M300-V322 HydrophobicContact CE-CB 4.14Å; M300-V322 HydrophobicContact CE-CG2 3.62Å; M300-V322 HydrophobicContact SD-CB 4.3Å; M300-V322 HydrophobicContact SD-CG1 4.29Å; M300-V322 HydrophobicContact SD-CG2 3.85Å; D319-V322 PolarHBondContact O-N 3.28Å; A320-V322 VanDerWaalsContact C-N 3.26Å; A320-V322 PolarHBondContact O-N 2.75Å; V322-F325 WeakPolarHBondContact O-CB 3.19Å; V322-F325 PolarHBondContact O-N 2.97Å; V322-V326 VanDerWaalsContact O-CG2 3.3Å; V322-V326 WeakPolarHBondContact O-CG2 3.19Å; V322-V326 PolarHBondContact O-N 3.44Å
323	I	88.9	Confident	78.1	Confident	3 Å²	3	33.6 Å²	33.6	2%	0.015	21%	0.211	C	C	.	.	H	α-helix	trans	-65.1	-44.3	177.1	-52.6	-53.2	0	0	0	110.4	I71 A152 A155 A156 A320 F325 V326 M327 F340 L344	I71-I323 HydrophobicContact CD1-CD1 3.83Å; I71-I323 HydrophobicContact CG1-CD1 4.12Å; A152-I323 HydrophobicContact CB-CD1 3.52Å; A152-I323 HydrophobicContact CB-CG1 4.11Å; A155-I323 HydrophobicContact CB-CB 4.37Å; A155-I323 HydrophobicContact CB-CG2 3.93Å; A156-I323 HydrophobicContact CB-CG2 4.03Å; A320-I323 PolarHBondContact O-N 2.84Å; A320-I323 VanDerWaalsContact O-N 3.17Å; I323-F325 PolarHBondContact O-N 3.25Å; I323-V326 PolarHBondContact O-N 3.18Å; I323-M327 HydrophobicContact CG2-CG 4.4Å; I323-M327 WeakPolarHBondContact O-CG 3.49Å; I323-M327 PolarHBondContact O-N 3.21Å; I323-F340 HydrophobicContact CD1-CE1 4.06Å; I323-L344 HydrophobicContact CD1-CD1 4.1Å
324	Y	87.3	Confident	79.8	Confident	72 Å²	72	36.3 Å²	36.3	28%	0.282	23%	0.23	S	C	.	.	H	α-helix	trans	-57.7	-48.3	174.7	176.1	-95.1	0	0	0	111.8	Y304 F309 A320 M321 V326 M327 D328	Y304-Y324 HydrophobicContact CE1-CD1 4.49Å; Y304-Y324 AromaticContact CE1-CE1 3.8Å; Y304-Y324 HydrophobicContact CE1-CE1 3.8Å; Y304-Y324 HydrophobicContact CE2-CD1 4.36Å; Y304-Y324 HydrophobicContact CE2-CE1 4.45Å; Y304-Y324 AromaticContact CZ-CD1 3.93Å; Y304-Y324 AromaticContact CZ-CE1 3.64Å; Y304-Y324 WeakPolarHBondContact OH-CE1 3.29Å; F309-Y324 AromaticContact CE1-CE1 3.98Å; F309-Y324 HydrophobicContact CE1-CE1 3.98Å; F309-Y324 HydrophobicContact CZ-CE1 4.01Å; A320-Y324 PolarHBondContact O-N 3.34Å; M321-Y324 HydrophobicContact CE-CD1 3.63Å; M321-Y324 HydrophobicContact CE-CE1 4.1Å; M321-Y324 PolarHBondContact O-N 3.33Å; Y324-V326 VanDerWaalsContact C-N 3.32Å; Y324-V326 PolarHBondContact O-N 3.41Å; Y324-M327 PolarHBondContact O-N 2.88Å; Y324-D328 HydrophobicContact CE1-CB 4.49Å; Y324-D328 VanDerWaalsContact O-CB 3.28Å; Y324-D328 WeakPolarHBondContact O-CB 3.42Å; Y324-D328 PolarHBondContact O-N 2.89Å
325	F	89.4	Confident	81.6	Confident	1 Å²	1	34.6 Å²	34.6	0%	0.004	21%	0.212	C	C	.	.	H	α-helix	trans	-55.5	-48	176.8	169	-109.8	0	0	0	111.7	V202 M296 V299 M300 R303 Y304 M321 V322 I323 D328 M329	V202-F325 HydrophobicContact CG1-CD1 4.23Å; V202-F325 HydrophobicContact CG1-CE1 3.65Å; M296-F325 HydrophobicContact CG-CE1 4.1Å; V299-F325 HydrophobicContact CB-CZ 4.35Å; V299-F325 HydrophobicContact CG1-CE2 4.17Å; V299-F325 HydrophobicContact CG1-CZ 3.75Å; M300-F325 HydrophobicContact CB-CD2 4.41Å; M300-F325 HydrophobicContact CB-CG 4.44Å; M300-F325 HydrophobicContact CE-CB 4.09Å; M300-F325 HydrophobicContact CG-CB 3.9Å; M300-F325 HydrophobicContact CG-CD1 3.33Å; M300-F325 HydrophobicContact CG-CD2 3.72Å; M300-F325 HydrophobicContact CG-CE1 3.63Å; M300-F325 HydrophobicContact CG-CE2 3.97Å; M300-F325 HydrophobicContact CG-CG 3.36Å; M300-F325 HydrophobicContact CG-CZ 3.94Å; M300-F325 HydrophobicContact SD-CB 4.32Å; M300-F325 HydrophobicContact SD-CD1 3.99Å; M300-F325 HydrophobicContact SD-CG 4.24Å; R303-F325 HydrophobicContact CB-CE2 4.4Å; Y304-F325 HydrophobicContact CE2-CB 3.92Å; Y304-F325 AromaticContact CE2-CD2 3.66Å; Y304-F325 HydrophobicContact CE2-CD2 3.66Å; Y304-F325 HydrophobicContact CE2-CG 4.26Å; M321-F325 WeakPolarHBondContact O-CB 3.37Å; M321-F325 PolarHBondContact O-N 3.46Å; V322-F325 WeakPolarHBondContact O-CB 3.19Å; V322-F325 PolarHBondContact O-N 2.97Å; I323-F325 PolarHBondContact O-N 3.25Å; F325-D328 PolarHBondContact O-N 3.11Å; F325-M329 HydrophobicContact CD2-CG 3.6Å; F325-M329 HydrophobicContact CD2-SD 4.35Å; F325-M329 HydrophobicContact CE1-CG 4.25Å; F325-M329 HydrophobicContact CE2-CG 3.25Å; F325-M329 HydrophobicContact CE2-SD 3.82Å; F325-M329 HydrophobicContact CG-CG 4.26Å; F325-M329 HydrophobicContact CZ-CG 3.62Å; F325-M329 WeakPolarHBondContact O-CB 3.48Å; F325-M329 VanDerWaalsContact O-CG 3.3Å; F325-M329 WeakPolarHBondContact O-CG 3.43Å; F325-M329 PolarHBondContact O-N 2.98Å
326	V	90.9	Very high	84	Confident	0 Å²	0	32 Å²	32	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-62.4	-48.1	-179.7	172.9	0	0	0	0	111.2	V202 V322 I323 Y324 D328 M329 L330 F340	V202-V326 HydrophobicContact CG1-CG2 3.83Å; V202-V326 HydrophobicContact CG2-CG1 3.96Å; V202-V326 HydrophobicContact CG2-CG2 3.98Å; V322-V326 VanDerWaalsContact O-CG2 3.3Å; V322-V326 WeakPolarHBondContact O-CG2 3.19Å; V322-V326 PolarHBondContact O-N 3.44Å; I323-V326 PolarHBondContact O-N 3.18Å; Y324-V326 VanDerWaalsContact C-N 3.32Å; Y324-V326 PolarHBondContact O-N 3.41Å; V326-D328 PolarHBondContact O-N 2.9Å; V326-M329 PolarHBondContact O-N 3.17Å; V326-L330 HydrophobicContact CG1-CD1 3.55Å; V326-L330 HydrophobicContact CG1-CG 4.12Å; V326-L330 VanDerWaalsContact O-CB 3.3Å; V326-L330 WeakPolarHBondContact O-CB 3.32Å; V326-L330 VanDerWaalsContact O-CG 3.28Å; V326-L330 WeakPolarHBondContact O-CG 3.39Å; V326-L330 PolarHBondContact O-N 3.46Å; V326-F340 HydrophobicContact CB-CD1 4.15Å; V326-F340 HydrophobicContact CB-CE1 4.11Å; V326-F340 HydrophobicContact CB-CZ 4.49Å; V326-F340 HydrophobicContact CG1-CB 3.94Å; V326-F340 HydrophobicContact CG1-CD1 3.52Å; V326-F340 HydrophobicContact CG1-CD2 4.23Å; V326-F340 HydrophobicContact CG1-CE1 4Å; V326-F340 HydrophobicContact CG1-CG 3.63Å; V326-F340 HydrophobicContact CG2-CD1 4.11Å; V326-F340 HydrophobicContact CG2-CD2 4.2Å; V326-F340 HydrophobicContact CG2-CE1 3.77Å; V326-F340 HydrophobicContact CG2-CE2 3.88Å; V326-F340 HydrophobicContact CG2-CG 4.29Å; V326-F340 HydrophobicContact CG2-CZ 3.66Å
327	M	88.9	Confident	86	Confident	17 Å²	17	29.4 Å²	29.4	8%	0.084	17%	0.171	C	C	.	.	H	α-helix	trans	-66	-29.4	179.8	-63.1	-58.2	138.4	0	0	112.2	F9 A156 I323 Y324 P337 V341	F9-M327 HydrophobicContact CD1-SD 4.48Å; F9-M327 HydrophobicContact CE1-CE 3.95Å; F9-M327 HydrophobicContact CE1-SD 3.93Å; A156-M327 HydrophobicContact CB-CE 3.54Å; A156-M327 HydrophobicContact CB-CG 4.11Å; A156-M327 HydrophobicContact CB-SD 3.89Å; I323-M327 HydrophobicContact CG2-CG 4.4Å; I323-M327 WeakPolarHBondContact O-CG 3.49Å; I323-M327 PolarHBondContact O-N 3.21Å; Y324-M327 PolarHBondContact O-N 2.88Å; M327-P337 HydrophobicContact CE-CB 4.42Å; M327-P337 HydrophobicContact SD-CB 4.17Å; M327-V341 HydrophobicContact CE-CG2 4.1Å
328	D	88.3	Confident	87.4	Confident	23 Å²	23	28.7 Å²	28.7	12%	0.123	17%	0.167	C	C	.	.	H	α-helix	trans	-71.3	-49.9	173.4	-171.2	41.5	0	0	0	112.4	K7 R303 Y304 Y324 F325 V326 Q331	K7-D328 VanDerWaalsContact NZ-CG 3.31Å; K7-D328 IonicContact NZ-OD1 2.61Å; K7-D328 PolarHBondContact NZ-OD1 3.44Å; R303-D328 IonicContact NE-OD2 3.96Å; R303-D328 IonicContact NH2-OD2 3.62Å; Y304-D328 VanDerWaalsContact OH-CB 3.29Å; Y304-D328 WeakPolarHBondContact OH-CB 3.3Å; Y304-D328 PolarHBondContact OH-OD2 2.89Å; Y324-D328 HydrophobicContact CE1-CB 4.49Å; Y324-D328 VanDerWaalsContact O-CB 3.28Å; Y324-D328 WeakPolarHBondContact O-CB 3.42Å; Y324-D328 PolarHBondContact O-N 2.89Å; F325-D328 PolarHBondContact O-N 3.11Å; V326-D328 PolarHBondContact O-N 2.9Å; D328-Q331 WeakPolarHBondContact O-CB 3.49Å; D328-Q331 PolarHBondContact O-N 3.32Å
329	M	90.3	Very high	88.5	Confident	5 Å²	5	27.7 Å²	27.7	3%	0.025	17%	0.165	C	C	.	.	H	α-helix	trans	-69.5	-38.1	-176.3	-66.8	-56.2	94.8	0	0	112.6	V205 R209 R303 F325 V326 Q331	V205-M329 HydrophobicContact CG1-CB 4.44Å; V205-M329 WeakPolarHBondContact CG1-O 3.48Å; R209-M329 HydrophobicContact CB-SD 3.69Å; R209-M329 HydrophobicContact CG-SD 4.37Å; R303-M329 HydrophobicContact CG-CE 3.85Å; R303-M329 HydrophobicContact CG-SD 4.37Å; F325-M329 HydrophobicContact CD2-CG 3.6Å; F325-M329 HydrophobicContact CD2-SD 4.35Å; F325-M329 HydrophobicContact CE1-CG 4.25Å; F325-M329 HydrophobicContact CE2-CG 3.25Å; F325-M329 HydrophobicContact CE2-SD 3.82Å; F325-M329 HydrophobicContact CG-CG 4.26Å; F325-M329 HydrophobicContact CZ-CG 3.62Å; F325-M329 WeakPolarHBondContact O-CB 3.48Å; F325-M329 VanDerWaalsContact O-CG 3.3Å; F325-M329 WeakPolarHBondContact O-CG 3.43Å; F325-M329 PolarHBondContact O-N 2.98Å; V326-M329 PolarHBondContact O-N 3.17Å; M329-Q331 VanDerWaalsContact C-N 3.26Å; M329-Q331 PolarHBondContact O-N 3.3Å
330	L	90.7	Very high	89.1	Confident	1 Å²	1	27.1 Å²	27.1	1%	0.005	16%	0.162	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.7	1.8	-176.9	-58.1	-174.2	0	0	0	113.2	V202 V205 V326 G332 L333 L336 P337 F340	V202-L330 HydrophobicContact CG2-CD1 4Å; V205-L330 HydrophobicContact CB-CD2 3.9Å; V205-L330 HydrophobicContact CG1-CD2 3.98Å; V205-L330 HydrophobicContact CG2-CD2 4.01Å; V326-L330 HydrophobicContact CG1-CD1 3.55Å; V326-L330 HydrophobicContact CG1-CG 4.12Å; V326-L330 VanDerWaalsContact O-CB 3.3Å; V326-L330 WeakPolarHBondContact O-CB 3.32Å; V326-L330 VanDerWaalsContact O-CG 3.28Å; V326-L330 WeakPolarHBondContact O-CG 3.39Å; V326-L330 PolarHBondContact O-N 3.46Å; L330-G332 PolarHBondContact O-N 3.42Å; L330-L333 PolarHBondContact O-N 3.03Å; L330-L333 VanDerWaalsContact O-N 3.11Å; L330-L336 HydrophobicContact CB-CB 4.44Å; L330-L336 HydrophobicContact CD1-CB 3.95Å; L330-L336 HydrophobicContact CD2-CB 4.01Å; L330-L336 HydrophobicContact CD2-CD1 4.09Å; L330-L336 HydrophobicContact CG-CB 4.37Å; L330-P337 HydrophobicContact CB-CG 3.78Å; L330-P337 HydrophobicContact CD1-CG 4.44Å; L330-F340 HydrophobicContact CD1-CB 4.36Å
331	Q	85.1	Confident	89.6	Confident	102 Å²	102	26.2 Å²	26.2	48%	0.477	16%	0.155	S	C	.	.	T	Hydrogen-bonded Turn	trans	-59.8	129.2	179.8	-172.3	175.9	-14.9	0	0	111.3	K7 R209 D328 M329 L333	K7-Q331 VanDerWaalsContact CE-OE1 3.25Å; R209-Q331 PolarHBondContact NH2-O 3.26Å; D328-Q331 WeakPolarHBondContact O-CB 3.49Å; D328-Q331 PolarHBondContact O-N 3.32Å; M329-Q331 VanDerWaalsContact C-N 3.26Å; M329-Q331 PolarHBondContact O-N 3.3Å; Q331-L333 VanDerWaalsContact C-N 3.34Å
332	G	84.4	Confident	90	Very high	71 Å²	71	26 Å²	26	73%	0.732	15%	0.153	S	C	*	.	T	Hydrogen-bonded Turn	trans	83.1	3.7	-178.8	0	0	0	0	0	114.8	L330 P334	L330-G332 PolarHBondContact O-N 3.42Å; G332-P334 WeakPolarHBondContact O-CD 3.29Å
333	L	90.1	Very high	90.2	Very high	61 Å²	61	26 Å²	26	32%	0.319	15%	0.153	S	C	.	.			trans	-112.5	86	175.3	-61.9	175.5	0	0	0	109.7	V205 L330 Q331 G335 L336 P337	V205-L333 HydrophobicContact CB-CD1 4.49Å; V205-L333 HydrophobicContact CG1-CD1 3.72Å; V205-L333 HydrophobicContact CG2-CD1 3.87Å; L330-L333 PolarHBondContact O-N 3.03Å; L330-L333 VanDerWaalsContact O-N 3.11Å; Q331-L333 VanDerWaalsContact C-N 3.34Å; L333-G335 PolarHBondContact O-N 2.86Å; L333-L336 HydrophobicContact CB-CD1 3.89Å; L333-L336 HydrophobicContact CB-CG 4.31Å; L333-L336 HydrophobicContact CD1-CD1 3.84Å; L333-L336 HydrophobicContact CG-CD1 4.49Å; L333-L336 PolarHBondContact O-N 3.3Å; L333-P337 VanDerWaalsContact O-CD 3.23Å; L333-P337 WeakPolarHBondContact O-CD 3.38Å
334	P	88.6	Confident	90.5	Very high	86 Å²	86	25.8 Å²	25.8	56%	0.558	15%	0.153	S	C	*	.	T	Hydrogen-bonded Turn	trans	-60.5	134	-173.7	25.5	-34	0	0	0	111.5	V12 G332	V12-P334 HydrophobicContact CB-CB 4.04Å; V12-P334 HydrophobicContact CG1-CB 4.28Å; V12-P334 HydrophobicContact CG2-CB 4.26Å; G332-P334 WeakPolarHBondContact O-CD 3.29Å
335	G	90.2	Very high	90.7	Very high	9 Å²	9	22.8 Å²	22.8	9%	0.093	14%	0.141	C	C	.	.	T	Hydrogen-bonded Turn	trans	98.1	-29.1	179.5	0	0	0	0	0	114.3	D13 L333 G338 L339	D13-G335 WeakPolarHBondContact OD1-CA 3.04Å; D13-G335 PolarHBondContact OD1-N 2.89Å; L333-G335 PolarHBondContact O-N 2.86Å; G335-G338 PolarHBondContact O-N 3.12Å; G335-L339 WeakPolarHBondContact O-CB 3.29Å; G335-L339 PolarHBondContact O-N 3.43Å
336	L	92.5	Very high	90.9	Very high	47 Å²	47	22.7 Å²	22.7	25%	0.246	14%	0.141	C	C	.	.	H	α-helix	trans	-70.9	-43.6	179.9	-63.4	-174.5	0	0	0	113.2	A201 V205 L330 L333 G338 L339 F340	A201-L336 HydrophobicContact CB-CD2 4.34Å; V205-L336 HydrophobicContact CG2-CD1 3.94Å; L330-L336 HydrophobicContact CB-CB 4.44Å; L330-L336 HydrophobicContact CD1-CB 3.95Å; L330-L336 HydrophobicContact CD2-CB 4.01Å; L330-L336 HydrophobicContact CD2-CD1 4.09Å; L330-L336 HydrophobicContact CG-CB 4.37Å; L333-L336 HydrophobicContact CB-CD1 3.89Å; L333-L336 HydrophobicContact CB-CG 4.31Å; L333-L336 HydrophobicContact CD1-CD1 3.84Å; L333-L336 HydrophobicContact CG-CD1 4.49Å; L333-L336 PolarHBondContact O-N 3.3Å; L336-G338 VanDerWaalsContact C-N 3.26Å; L336-G338 PolarHBondContact O-N 3Å; L336-L339 HydrophobicContact CD2-CD2 4.26Å; L336-L339 WeakPolarHBondContact O-CB 3.34Å; L336-L339 PolarHBondContact O-N 2.67Å; L336-L339 VanDerWaalsContact O-N 3.17Å; L336-F340 PolarHBondContact O-N 2.99Å
337	P	91.8	Very high	91	Very high	10 Å²	10	22.7 Å²	22.7	7%	0.065	14%	0.141	C	C	.	.	H	α-helix	trans	-55.1	-43.1	170.3	-25.1	31.3	0	0	0	112.5	F9 D13 M327 L330 L333 F340 V341	F9-P337 HydrophobicContact CD1-CB 4.28Å; F9-P337 HydrophobicContact CE1-CB 3.78Å; F9-P337 HydrophobicContact CZ-CB 4.28Å; D13-P337 WeakPolarHBondContact OD1-CD 3.45Å; M327-P337 HydrophobicContact CE-CB 4.42Å; M327-P337 HydrophobicContact SD-CB 4.17Å; L330-P337 HydrophobicContact CB-CG 3.78Å; L330-P337 HydrophobicContact CD1-CG 4.44Å; L333-P337 VanDerWaalsContact O-CD 3.23Å; L333-P337 WeakPolarHBondContact O-CD 3.38Å; P337-F340 PolarHBondContact O-N 3.05Å; P337-V341 PolarHBondContact O-N 3.24Å; P337-V341 VanDerWaalsContact O-N 3.09Å
338	G	91.6	Very high	91.1	Very high	0 Å²	0	21.9 Å²	21.9	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-60.4	-42.6	174.5	0	0	0	0	0	113.2	D13 G335 L336 V341 A342	D13-G338 WeakPolarHBondContact O-CA 3.33Å; D13-G338 PolarHBondContact OD1-N 3.29Å; G335-G338 PolarHBondContact O-N 3.12Å; L336-G338 VanDerWaalsContact C-N 3.26Å; L336-G338 PolarHBondContact O-N 3Å; G338-V341 PolarHBondContact O-N 3.41Å; G338-A342 WeakPolarHBondContact O-CB 3.23Å; G338-A342 PolarHBondContact O-N 3.43Å
339	L	94.3	Very high	91.2	Very high	35 Å²	35	20.9 Å²	20.9	18%	0.183	13%	0.131	C	C	.	.	H	α-helix	trans	-61.9	-41.9	175.3	177	64.6	0	0	0	112.2	V16 L20 V194 A201 G335 L336 A342 C343	V16-L339 HydrophobicContact CG1-CB 4.29Å; L20-L339 HydrophobicContact CD1-CD1 3.7Å; V194-L339 HydrophobicContact CG1-CD1 4.43Å; A201-L339 HydrophobicContact CB-CD2 4.18Å; G335-L339 WeakPolarHBondContact O-CB 3.29Å; G335-L339 PolarHBondContact O-N 3.43Å; L336-L339 HydrophobicContact CD2-CD2 4.26Å; L336-L339 WeakPolarHBondContact O-CB 3.34Å; L336-L339 PolarHBondContact O-N 2.67Å; L336-L339 VanDerWaalsContact O-N 3.17Å; L339-A342 WeakPolarHBondContact O-CB 3.39Å; L339-A342 PolarHBondContact O-N 3.06Å; L339-C343 WeakPolarHBondContact O-CB 3.41Å; L339-C343 PolarHBondContact O-N 2.9Å
340	F	92.5	Very high	91.3	Very high	1 Å²	1	20.7 Å²	20.7	0%	0.004	13%	0.13	C	C	.	.	H	α-helix	trans	-66.1	-44.3	178.1	177.8	-101	0	0	0	112	I70 V202 I323 V326 L330 L336 P337 A342 C343 L344	I70-F340 HydrophobicContact CG2-CE2 4.35Å; V202-F340 HydrophobicContact CG2-CB 4.25Å; V202-F340 HydrophobicContact CG2-CD2 3.56Å; V202-F340 HydrophobicContact CG2-CE2 4.19Å; V202-F340 HydrophobicContact CG2-CG 4.11Å; I323-F340 HydrophobicContact CD1-CE1 4.06Å; V326-F340 HydrophobicContact CB-CD1 4.15Å; V326-F340 HydrophobicContact CB-CE1 4.11Å; V326-F340 HydrophobicContact CB-CZ 4.49Å; V326-F340 HydrophobicContact CG1-CB 3.94Å; V326-F340 HydrophobicContact CG1-CD1 3.52Å; V326-F340 HydrophobicContact CG1-CD2 4.23Å; V326-F340 HydrophobicContact CG1-CE1 4Å; V326-F340 HydrophobicContact CG1-CG 3.63Å; V326-F340 HydrophobicContact CG2-CD1 4.11Å; V326-F340 HydrophobicContact CG2-CD2 4.2Å; V326-F340 HydrophobicContact CG2-CE1 3.77Å; V326-F340 HydrophobicContact CG2-CE2 3.88Å; V326-F340 HydrophobicContact CG2-CG 4.29Å; V326-F340 HydrophobicContact CG2-CZ 3.66Å; L330-F340 HydrophobicContact CD1-CB 4.36Å; L336-F340 PolarHBondContact O-N 2.99Å; P337-F340 PolarHBondContact O-N 3.05Å; F340-A342 VanDerWaalsContact C-N 3.3Å; F340-A342 PolarHBondContact O-N 3.31Å; F340-C343 VanDerWaalsContact O-CB 3.26Å; F340-C343 WeakPolarHBondContact O-CB 3.3Å; F340-C343 PolarHBondContact O-N 3.14Å; F340-C343 VanDerWaalsContact O-N 3.15Å; F340-L344 HydrophobicContact CD1-CD1 4.04Å; F340-L344 HydrophobicContact CD1-CG 4.36Å; F340-L344 HydrophobicContact CE1-CD1 3.46Å; F340-L344 VanDerWaalsContact CE1-CD1 3.46Å; F340-L344 HydrophobicContact CE1-CD2 4.4Å; F340-L344 HydrophobicContact CE1-CG 3.93Å; F340-L344 HydrophobicContact CZ-CD1 3.97Å; F340-L344 HydrophobicContact CZ-CD2 4.06Å; F340-L344 HydrophobicContact CZ-CG 4.06Å; F340-L344 PolarHBondContact O-N 3.25Å
341	V	91.6	Very high	91.4	Very high	1 Å²	1	20.8 Å²	20.8	1%	0.006	13%	0.131	C	C	.	.	H	α-helix	trans	-65	-38	176	174.6	0	0	0	0	110.7	F9 F17 L153 M327 P337 G338 C343 L344 F345	F9-V341 HydrophobicContact CE1-CG2 4.19Å; F9-V341 HydrophobicContact CE2-CG2 4.46Å; F9-V341 HydrophobicContact CZ-CB 3.99Å; F9-V341 HydrophobicContact CZ-CG2 3.51Å; F17-V341 HydrophobicContact CD2-CB 4.39Å; F17-V341 HydrophobicContact CD2-CG1 3.89Å; F17-V341 HydrophobicContact CE2-CG1 3.7Å; F17-V341 HydrophobicContact CZ-CG1 4.21Å; L153-V341 HydrophobicContact CD1-CG1 3.97Å; M327-V341 HydrophobicContact CE-CG2 4.1Å; P337-V341 PolarHBondContact O-N 3.24Å; P337-V341 VanDerWaalsContact O-N 3.09Å; G338-V341 PolarHBondContact O-N 3.41Å; V341-C343 VanDerWaalsContact C-N 3.33Å; V341-C343 PolarHBondContact O-N 2.9Å; V341-L344 PolarHBondContact O-N 3.29Å; V341-F345 HydrophobicContact CG1-CD2 3.91Å; V341-F345 HydrophobicContact CG1-CE2 3.85Å; V341-F345 VanDerWaalsContact O-CD2 3.32Å; V341-F345 WeakPolarHBondContact O-CD2 3.48Å; V341-F345 PolarHBondContact O-N 2.99Å
342	A	93	Very high	91.6	Very high	0 Å²	0	15.9 Å²	15.9	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-59.5	-42.6	171.3	0	0	0	0	0	112.1	F17 L20 V194 G338 L339 F340 L344 F345 S346	F17-A342 HydrophobicContact CD2-CB 4.11Å; L20-A342 HydrophobicContact CB-CB 3.82Å; L20-A342 HydrophobicContact CD1-CB 3.38Å; L20-A342 HydrophobicContact CG-CB 4.24Å; V194-A342 HydrophobicContact CG1-CB 4.32Å; G338-A342 WeakPolarHBondContact O-CB 3.23Å; G338-A342 PolarHBondContact O-N 3.43Å; L339-A342 WeakPolarHBondContact O-CB 3.39Å; L339-A342 PolarHBondContact O-N 3.06Å; F340-A342 VanDerWaalsContact C-N 3.3Å; F340-A342 PolarHBondContact O-N 3.31Å; A342-L344 VanDerWaalsContact C-N 3.35Å; A342-L344 PolarHBondContact O-N 3.31Å; A342-F345 PolarHBondContact O-N 3.11Å; A342-S346 VanDerWaalsContact O-CB 3.3Å; A342-S346 WeakPolarHBondContact O-CB 3.5Å; A342-S346 PolarHBondContact O-N 3.42Å; A342-S346 PolarHBondContact O-OG 2.91Å
343	C	94.4	Very high	91.9	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-55.7	-45.9	173.4	156.1	0	0	0	0	112.2	V194 M195 L339 F340 V341 S346 A347	V194-C343 HydrophobicContact CG1-CB 4.49Å; M195-C343 VanDerWaalsContact CA-SG 3.57Å; M195-C343 PolarHBondContact O-SG 3.28Å; L339-C343 WeakPolarHBondContact O-CB 3.41Å; L339-C343 PolarHBondContact O-N 2.9Å; F340-C343 VanDerWaalsContact O-CB 3.26Å; F340-C343 WeakPolarHBondContact O-CB 3.3Å; F340-C343 PolarHBondContact O-N 3.14Å; F340-C343 VanDerWaalsContact O-N 3.15Å; V341-C343 VanDerWaalsContact C-N 3.33Å; V341-C343 PolarHBondContact O-N 2.9Å; C343-S346 PolarHBondContact O-N 3.14Å; C343-A347 WeakPolarHBondContact O-CB 2.99Å; C343-A347 PolarHBondContact O-N 3.43Å
344	L	93.6	Very high	91.9	Very high	0 Å²	0	9.7 Å²	9.7	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-63.6	-43.8	176.8	-66.6	178.7	0	0	0	112.6	A67 I70 I71 A152 I323 F340 V341 A342 A347 A348	A67-L344 HydrophobicContact CB-CD2 4.44Å; I70-L344 HydrophobicContact CB-CD2 3.97Å; I70-L344 HydrophobicContact CG2-CD2 3.56Å; I71-L344 HydrophobicContact CD1-CD1 3.92Å; I71-L344 HydrophobicContact CD1-CD2 3.84Å; I71-L344 HydrophobicContact CG1-CD1 4.41Å; I71-L344 HydrophobicContact CG1-CD2 3.74Å; A152-L344 HydrophobicContact CB-CD1 3.43Å; A152-L344 VanDerWaalsContact CB-CD1 3.43Å; I323-L344 HydrophobicContact CD1-CD1 4.1Å; F340-L344 HydrophobicContact CD1-CD1 4.04Å; F340-L344 HydrophobicContact CD1-CG 4.36Å; F340-L344 HydrophobicContact CE1-CD1 3.46Å; F340-L344 VanDerWaalsContact CE1-CD1 3.46Å; F340-L344 HydrophobicContact CE1-CD2 4.4Å; F340-L344 HydrophobicContact CE1-CG 3.93Å; F340-L344 HydrophobicContact CZ-CD1 3.97Å; F340-L344 HydrophobicContact CZ-CD2 4.06Å; F340-L344 HydrophobicContact CZ-CG 4.06Å; F340-L344 PolarHBondContact O-N 3.25Å; V341-L344 PolarHBondContact O-N 3.29Å; A342-L344 VanDerWaalsContact C-N 3.35Å; A342-L344 PolarHBondContact O-N 3.31Å; L344-A347 PolarHBondContact O-N 3.37Å; L344-A348 PolarHBondContact O-N 3.26Å
345	F	92.6	Very high	92	Very high	8 Å²	8	5.6 Å²	5.6	4%	0.035	3%	0.032	C	C	.	.	H	α-helix	trans	-68.3	-41.1	177.3	-85.2	-111.6	0	0	0	111.7	F17 L21 P149 L153 T164 T168 V341 A342 A347 A348 L349	F17-F345 HydrophobicContact CE2-CB 4.27Å; F17-F345 HydrophobicContact CE2-CD1 4.32Å; F17-F345 AromaticContact CE2-CD2 3.78Å; F17-F345 HydrophobicContact CE2-CD2 3.78Å; F17-F345 HydrophobicContact CE2-CE2 4.14Å; F17-F345 AromaticContact CE2-CG 3.87Å; F17-F345 HydrophobicContact CE2-CG 3.87Å; F17-F345 HydrophobicContact CZ-CD1 4.22Å; F17-F345 HydrophobicContact CZ-CD2 4.11Å; F17-F345 HydrophobicContact CZ-CE1 4.13Å; F17-F345 HydrophobicContact CZ-CE2 4.05Å; F17-F345 HydrophobicContact CZ-CG 4.19Å; F17-F345 HydrophobicContact CZ-CZ 4.05Å; L21-F345 HydrophobicContact CD1-CD1 4.42Å; L21-F345 HydrophobicContact CD2-CB 3.81Å; L21-F345 HydrophobicContact CD2-CD1 4.39Å; L21-F345 HydrophobicContact CD2-CG 4.44Å; P149-F345 HydrophobicContact CB-CD2 3.83Å; P149-F345 HydrophobicContact CB-CE2 3.86Å; P149-F345 HydrophobicContact CB-CG 4.27Å; P149-F345 HydrophobicContact CB-CZ 4.32Å; L153-F345 HydrophobicContact CB-CE2 4.1Å; L153-F345 HydrophobicContact CB-CZ 4.31Å; L153-F345 HydrophobicContact CD2-CE2 4.39Å; L153-F345 HydrophobicContact CD2-CZ 4Å; T164-F345 HydrophobicContact CG2-CE1 4.05Å; T164-F345 HydrophobicContact CG2-CZ 3.49Å; T164-F345 VanDerWaalsContact CG2-CZ 3.49Å; T168-F345 HydrophobicContact CG2-CD1 4.25Å; T168-F345 HydrophobicContact CG2-CE1 4.27Å; T168-F345 WeakPolarHBondContact OG1-CE1 3.48Å; V341-F345 HydrophobicContact CG1-CD2 3.91Å; V341-F345 HydrophobicContact CG1-CE2 3.85Å; V341-F345 VanDerWaalsContact O-CD2 3.32Å; V341-F345 WeakPolarHBondContact O-CD2 3.48Å; V341-F345 PolarHBondContact O-N 2.99Å; A342-F345 PolarHBondContact O-N 3.11Å; F345-A347 VanDerWaalsContact C-N 3.31Å; F345-A347 PolarHBondContact O-N 2.93Å; F345-A348 PolarHBondContact O-N 3.43Å; F345-L349 WeakPolarHBondContact O-CB 3.27Å; F345-L349 WeakPolarHBondContact O-CG 3.31Å; F345-L349 PolarHBondContact O-N 3.29Å
346	S	92.6	Very high	92	Very high	0 Å²	0	5.2 Å²	5.2	0%	0	3%	0.028	C	C	.	.	H	α-helix	trans	-55.7	-46.1	174	-71.1	0	0	0	0	111.4	A342 C343 A348 L349 S350	A342-S346 VanDerWaalsContact O-CB 3.3Å; A342-S346 WeakPolarHBondContact O-CB 3.5Å; A342-S346 PolarHBondContact O-N 3.42Å; A342-S346 PolarHBondContact O-OG 2.91Å; C343-S346 PolarHBondContact O-N 3.14Å; S346-A348 PolarHBondContact O-N 3.38Å; S346-L349 PolarHBondContact O-N 3.28Å; S346-S350 PolarHBondContact O-N 3.31Å; S346-S350 PolarHBondContact O-OG 3.33Å
347	A	93.3	Very high	91.8	Very high	0 Å²	0	3.1 Å²	3.1	0%	0	2%	0.017	C	C	.	.	H	α-helix	trans	-64.2	-37.9	176.8	0	0	0	0	0	113.6	Q65 A67 I70 M195 C343 L344 F345 S350 T351	Q65-A347 WeakPolarHBondContact O-CB 3.39Å; A67-A347 HydrophobicContact CB-CB 4.47Å; I70-A347 HydrophobicContact CD1-CB 3.59Å; M195-A347 HydrophobicContact CE-CB 3.72Å; M195-A347 HydrophobicContact CG-CB 3.96Å; M195-A347 HydrophobicContact SD-CB 3.91Å; C343-A347 WeakPolarHBondContact O-CB 2.99Å; C343-A347 PolarHBondContact O-N 3.43Å; L344-A347 PolarHBondContact O-N 3.37Å; F345-A347 VanDerWaalsContact C-N 3.31Å; F345-A347 PolarHBondContact O-N 2.93Å; A347-S350 PolarHBondContact O-OG 3.5Å; A347-T351 WeakPolarHBondContact O-CB 3.43Å; A347-T351 PolarHBondContact O-N 3.22Å; A347-T351 PolarHBondContact O-OG1 3.49Å
348	A	92.1	Very high	91.8	Very high	0 Å²	0	2.7 Å²	2.7	0%	0	1%	0.014	C	C	.	.	H	α-helix	trans	-71.7	-47	176.5	0	0	0	0	0	111.5	A67 P149 L344 F345 S346 S350 T351 I352	A67-A348 HydrophobicContact CB-CB 4.18Å; P149-A348 HydrophobicContact CB-CB 4.16Å; P149-A348 HydrophobicContact CG-CB 3.57Å; L344-A348 PolarHBondContact O-N 3.26Å; F345-A348 PolarHBondContact O-N 3.43Å; S346-A348 PolarHBondContact O-N 3.38Å; A348-S350 PolarHBondContact O-N 3.38Å; A348-T351 PolarHBondContact O-N 2.94Å; A348-T351 VanDerWaalsContact O-N 3.16Å; A348-I352 HydrophobicContact CB-CD1 4.23Å; A348-I352 WeakPolarHBondContact O-CB 3.44Å; A348-I352 VanDerWaalsContact O-CD1 3.32Å; A348-I352 WeakPolarHBondContact O-CD1 3.15Å; A348-I352 WeakPolarHBondContact O-CG1 3.32Å; A348-I352 PolarHBondContact O-N 3.03Å
349	L	90.4	Very high	91.9	Very high	2 Å²	2	2.7 Å²	2.7	1%	0.01	1%	0.014	C	C	.	.	H	α-helix	trans	-60.8	-42.8	-178.9	-73.7	178.6	0	0	0	111.9	L21 T168 C172 Y175 F345 S346 T351 I352 S353	L21-L349 HydrophobicContact CD2-CD1 3.78Å; T168-L349 HydrophobicContact CG2-CD2 4.1Å; C172-L349 HydrophobicContact CB-CD2 3.65Å; Y175-L349 HydrophobicContact CE1-CD2 4.2Å; Y175-L349 WeakPolarHBondContact OH-CB 3.5Å; Y175-L349 PolarHBondContact OH-O 3.46Å; F345-L349 WeakPolarHBondContact O-CB 3.27Å; F345-L349 WeakPolarHBondContact O-CG 3.31Å; F345-L349 PolarHBondContact O-N 3.29Å; S346-L349 PolarHBondContact O-N 3.28Å; L349-T351 VanDerWaalsContact C-N 3.34Å; L349-T351 PolarHBondContact O-N 3.26Å; L349-I352 PolarHBondContact O-N 3.04Å; L349-S353 VanDerWaalsContact O-CB 3.26Å; L349-S353 WeakPolarHBondContact O-CB 3.38Å; L349-S353 PolarHBondContact O-N 3.24Å; L349-S353 PolarHBondContact O-OG 3.14Å
350	S	91.4	Very high	91.7	Very high	0 Å²	0	1 Å²	1	0%	0	1%	0.006	C	C	.	.	H	α-helix	trans	-61.6	-42	174	58.3	0	0	0	0	112.2	A62 D188 Q191 S346 A347 A348 S353 S354	A62-S350 WeakPolarHBondContact O-CB 3.2Å; A62-S350 PolarHBondContact O-OG 3.49Å; D188-S350 WeakPolarHBondContact OD1-CA 3.5Å; D188-S350 VanDerWaalsContact OD1-CB 3.23Å; D188-S350 WeakPolarHBondContact OD1-CB 3.32Å; Q191-S350 VanDerWaalsContact OE1-CB 3.29Å; S346-S350 PolarHBondContact O-N 3.31Å; S346-S350 PolarHBondContact O-OG 3.33Å; A347-S350 PolarHBondContact O-OG 3.5Å; A348-S350 PolarHBondContact O-N 3.38Å; S350-S353 PolarHBondContact O-OG 3.15Å; S350-S354 WeakPolarHBondContact O-CB 3.4Å; S350-S354 PolarHBondContact O-N 3.49Å; S350-S354 PolarHBondContact O-OG 3.28Å
351	T	92.4	Very high	91.6	Very high	3 Å²	3	1 Å²	1	2%	0.018	1%	0.005	C	C	.	.	H	α-helix	trans	-68.1	-44	180	-58.3	0	0	0	0	111.4	S63 S66 Y141 M142 C145 A347 A348 L349 S354 A355	S63-T351 WeakPolarHBondContact O-CG2 3.44Å; S63-T351 PolarHBondContact O-OG1 2.69Å; S66-T351 VanDerWaalsContact CB-OG1 3.29Å; S66-T351 WeakPolarHBondContact CB-OG1 3.42Å; Y141-T351 HydrophobicContact CE1-CG2 3.71Å; M142-T351 HydrophobicContact CE-CG2 4.03Å; C145-T351 HydrophobicContact CB-CG2 4.36Å; C145-T351 VanDerWaalsContact SG-CG2 3.55Å; A347-T351 WeakPolarHBondContact O-CB 3.43Å; A347-T351 PolarHBondContact O-N 3.22Å; A347-T351 PolarHBondContact O-OG1 3.49Å; A348-T351 PolarHBondContact O-N 2.94Å; A348-T351 VanDerWaalsContact O-N 3.16Å; L349-T351 VanDerWaalsContact C-N 3.34Å; L349-T351 PolarHBondContact O-N 3.26Å; T351-S354 WeakPolarHBondContact O-CB 3.38Å; T351-A355 PolarHBondContact O-N 3.15Å; T351-A355 VanDerWaalsContact O-N 3.13Å
352	I	90.6	Very high	91.8	Very high	0 Å²	0	1 Å²	1	0%	0	1%	0.005	C	C	.	.	H	α-helix	trans	-70.7	-44.2	-177.2	-62.5	157.9	0	0	0	111	M142 C145 V146 C172 A348 L349 S354 A355 F356	M142-I352 HydrophobicContact SD-CB 4.21Å; M142-I352 HydrophobicContact SD-CG1 4.02Å; M142-I352 HydrophobicContact SD-CG2 4.36Å; C145-I352 HydrophobicContact CB-CG1 4.06Å; V146-I352 HydrophobicContact CB-CD1 4.37Å; V146-I352 HydrophobicContact CG2-CD1 3.49Å; V146-I352 VanDerWaalsContact CG2-CD1 3.49Å; V146-I352 HydrophobicContact CG2-CG1 4.01Å; C172-I352 HydrophobicContact CB-CG2 4.12Å; C172-I352 VanDerWaalsContact SG-CB 3.56Å; C172-I352 WeakPolarHBondContact SG-CG2 3.35Å; A348-I352 HydrophobicContact CB-CD1 4.23Å; A348-I352 WeakPolarHBondContact O-CB 3.44Å; A348-I352 VanDerWaalsContact O-CD1 3.32Å; A348-I352 WeakPolarHBondContact O-CD1 3.15Å; A348-I352 WeakPolarHBondContact O-CG1 3.32Å; A348-I352 PolarHBondContact O-N 3.03Å; L349-I352 PolarHBondContact O-N 3.04Å; I352-S354 VanDerWaalsContact C-N 3.3Å; I352-S354 PolarHBondContact O-N 3.48Å; I352-A355 PolarHBondContact O-N 2.93Å; I352-F356 HydrophobicContact CG2-CD1 4.05Å; I352-F356 HydrophobicContact CG2-CD2 4Å; I352-F356 HydrophobicContact CG2-CE1 3.54Å; I352-F356 HydrophobicContact CG2-CE2 3.5Å; I352-F356 HydrophobicContact CG2-CG 4.26Å; I352-F356 HydrophobicContact CG2-CZ 3.23Å; I352-F356 WeakPolarHBondContact O-CD1 2.98Å; I352-F356 WeakPolarHBondContact O-CG 3.49Å; I352-F356 PolarHBondContact O-N 3.31Å
353	S	89.4	Confident	91.8	Very high	0 Å²	0	1.5 Å²	1.5	0%	0	1%	0.008	C	C	.	.	H	α-helix	trans	-60.4	-41.6	178.1	66.3	0	0	0	0	111.8	C172 Y175 T176 L349 S350 F356 N357	C172-S353 PolarHBondContact SG-N 3.24Å; Y175-S353 WeakPolarHBondContact OH-CB 3.38Å; T176-S353 WeakPolarHBondContact OG1-CA 3.46Å; T176-S353 VanDerWaalsContact OG1-CB 3.24Å; T176-S353 WeakPolarHBondContact OG1-CB 3.45Å; L349-S353 VanDerWaalsContact O-CB 3.26Å; L349-S353 WeakPolarHBondContact O-CB 3.38Å; L349-S353 PolarHBondContact O-N 3.24Å; L349-S353 PolarHBondContact O-OG 3.14Å; S350-S353 PolarHBondContact O-OG 3.15Å; S353-F356 PolarHBondContact O-N 3.07Å; S353-N357 WeakPolarHBondContact O-CB 3.28Å; S353-N357 PolarHBondContact O-N 3.31Å
354	S	90.9	Very high	91.7	Very high	2 Å²	2	1.5 Å²	1.5	1%	0.014	1%	0.008	C	C	.	.	H	α-helix	trans	-57.1	-50.4	173.7	-60.4	0	0	0	0	112.1	S63 R265 S350 T351 I352 N357 S358	S63-S354 PolarHBondContact OG-OG 3.33Å; R265-S354 VanDerWaalsContact CZ-OG 3.29Å; R265-S354 PolarHBondContact NH1-OG 3.18Å; R265-S354 PolarHBondContact NH2-OG 3.09Å; S350-S354 WeakPolarHBondContact O-CB 3.4Å; S350-S354 PolarHBondContact O-N 3.49Å; S350-S354 PolarHBondContact O-OG 3.28Å; T351-S354 WeakPolarHBondContact O-CB 3.38Å; I352-S354 VanDerWaalsContact C-N 3.3Å; I352-S354 PolarHBondContact O-N 3.48Å; S354-N357 PolarHBondContact O-N 3.11Å; S354-S358 WeakPolarHBondContact O-CB 3.39Å; S354-S358 PolarHBondContact O-N 2.85Å; S354-S358 PolarHBondContact O-OG 3.37Å
355	A	91.4	Very high	91.5	Very high	0 Å²	0	2.4 Å²	2.4	0%	0	1%	0.013	C	C	.	.	H	α-helix	trans	-65.6	-43.7	-178.7	0	0	0	0	0	111.7	M138 M142 T351 I352 N357 S358 L359	M138-A355 HydrophobicContact CE-CB 3.58Å; M142-A355 HydrophobicContact CE-CB 3.48Å; M142-A355 VanDerWaalsContact CE-CB 3.48Å; M142-A355 HydrophobicContact CG-CB 3.7Å; M142-A355 HydrophobicContact SD-CB 3.19Å; M142-A355 WeakPolarHBondContact SD-CB 3.33Å; T351-A355 PolarHBondContact O-N 3.15Å; T351-A355 VanDerWaalsContact O-N 3.13Å; I352-A355 PolarHBondContact O-N 2.93Å; A355-N357 VanDerWaalsContact C-N 3.35Å; A355-N357 PolarHBondContact O-N 3.45Å; A355-S358 PolarHBondContact O-N 2.9Å; A355-L359 VanDerWaalsContact O-CB 3.25Å; A355-L359 WeakPolarHBondContact O-CB 3.29Å; A355-L359 WeakPolarHBondContact O-CG 3.49Å; A355-L359 PolarHBondContact O-N 3.26Å
356	F	89.2	Confident	91.6	Very high	1 Å²	1	2.1 Å²	2.1	0%	0.004	1%	0.011	C	C	.	.	H	α-helix	trans	-63.9	-42.3	179.5	-72.4	4.8	0	0	0	111.4	M142 T176 I352 S353 A360 G392 C395	M142-F356 HydrophobicContact CG-CE1 4.2Å; T176-F356 HydrophobicContact CG2-CB 4.04Å; I352-F356 HydrophobicContact CG2-CD1 4.05Å; I352-F356 HydrophobicContact CG2-CD2 4Å; I352-F356 HydrophobicContact CG2-CE1 3.54Å; I352-F356 HydrophobicContact CG2-CE2 3.5Å; I352-F356 HydrophobicContact CG2-CG 4.26Å; I352-F356 HydrophobicContact CG2-CZ 3.23Å; I352-F356 WeakPolarHBondContact O-CD1 2.98Å; I352-F356 WeakPolarHBondContact O-CG 3.49Å; I352-F356 PolarHBondContact O-N 3.31Å; S353-F356 PolarHBondContact O-N 3.07Å; F356-A360 VanDerWaalsContact O-CB 3.27Å; F356-A360 WeakPolarHBondContact O-CB 3.34Å; F356-A360 PolarHBondContact O-N 3.5Å; F356-G392 VanDerWaalsContact CZ-CA 3.48Å; F356-C395 HydrophobicContact CE1-CB 4.29Å; F356-C395 VanDerWaalsContact CE1-SG 3.51Å; F356-C395 HydrophobicContact CZ-CB 4.25Å
357	N	88.8	Confident	91.6	Very high	3 Å²	3	4.3 Å²	4.3	2%	0.016	2%	0.023	C	C	.	.	H	α-helix	trans	-60	-48.8	174.8	-176.6	-99.6	0	0	0	110.9	Q264 S353 S354 A355 A360 T361	Q264-N357 VanDerWaalsContact CD-OD1 3.32Å; Q264-N357 PolarHBondContact NE2-OD1 3.16Å; Q264-N357 PolarHBondContact OE1-OD1 3.41Å; S353-N357 WeakPolarHBondContact O-CB 3.28Å; S353-N357 PolarHBondContact O-N 3.31Å; S354-N357 PolarHBondContact O-N 3.11Å; A355-N357 VanDerWaalsContact C-N 3.35Å; A355-N357 PolarHBondContact O-N 3.45Å; N357-A360 PolarHBondContact O-N 2.89Å; N357-T361 PolarHBondContact O-N 3.47Å; N357-T361 PolarHBondContact O-OG1 3.29Å
358	S	91.7	Very high	91.6	Very high	0 Å²	0	5.8 Å²	5.8	0%	0	3%	0.031	C	C	.	.	H	α-helix	trans	-67.3	-39.2	179.9	-66	0	0	0	0	114.3	A261 Q264 S354 A355 T361 V362	A261-S358 WeakPolarHBondContact CA-OG 3.39Å; A261-S358 PolarHBondContact N-OG 3.14Å; Q264-S358 VanDerWaalsContact OE1-CA 3.32Å; Q264-S358 PolarHBondContact OE1-OG 2.93Å; S354-S358 WeakPolarHBondContact O-CB 3.39Å; S354-S358 PolarHBondContact O-N 2.85Å; S354-S358 PolarHBondContact O-OG 3.37Å; A355-S358 PolarHBondContact O-N 2.9Å; S358-T361 PolarHBondContact O-N 3.18Å; S358-V362 WeakPolarHBondContact O-CG1 3.45Å; S358-V362 WeakPolarHBondContact O-CG2 3.37Å; S358-V362 PolarHBondContact O-N 3.48Å
359	L	93.4	Very high	91.4	Very high	0 Å²	0	8.4 Å²	8.4	0%	0	4%	0.042	C	C	.	.	H	α-helix	trans	-62	-44.5	173.8	-77.9	169.6	0	0	0	111.2	F134 I135 M138 V139 A355 V362 T363 Y391	F134-L359 HydrophobicContact CE1-CD2 4.25Å; I135-L359 HydrophobicContact CB-CD2 4.08Å; I135-L359 HydrophobicContact CG1-CD2 3.87Å; I135-L359 HydrophobicContact CG2-CD2 4.1Å; M138-L359 HydrophobicContact CB-CD1 4.27Å; M138-L359 HydrophobicContact CB-CD2 4.01Å; M138-L359 HydrophobicContact CB-CG 4.23Å; V139-L359 HydrophobicContact CG2-CD1 4.41Å; A355-L359 VanDerWaalsContact O-CB 3.25Å; A355-L359 WeakPolarHBondContact O-CB 3.29Å; A355-L359 WeakPolarHBondContact O-CG 3.49Å; A355-L359 PolarHBondContact O-N 3.26Å; L359-V362 WeakPolarHBondContact O-CG2 3.46Å; L359-T363 VanDerWaalsContact O-CB 3.26Å; L359-T363 WeakPolarHBondContact O-CB 3.14Å; L359-T363 PolarHBondContact O-N 3.16Å; L359-T363 PolarHBondContact O-OG1 3.37Å; L359-Y391 HydrophobicContact CB-CD1 4.47Å; L359-Y391 HydrophobicContact CB-CD2 3.74Å; L359-Y391 HydrophobicContact CB-CE2 3.78Å; L359-Y391 HydrophobicContact CB-CG 4.11Å; L359-Y391 HydrophobicContact CD1-CD1 3.95Å; L359-Y391 HydrophobicContact CD1-CD2 4.5Å; L359-Y391 HydrophobicContact CD1-CE1 4.4Å; L359-Y391 HydrophobicContact CD1-CG 4.01Å; L359-Y391 HydrophobicContact CD2-CE1 4.22Å
360	A	90.9	Very high	91.4	Very high	1 Å²	1	10.4 Å²	10.4	1%	0.008	6%	0.055	C	C	.	.	H	α-helix	trans	-62.3	-43.1	174.2	0	0	0	0	0	111.2	F356 N357 M364 L387 A388	F356-A360 VanDerWaalsContact O-CB 3.27Å; F356-A360 WeakPolarHBondContact O-CB 3.34Å; F356-A360 PolarHBondContact O-N 3.5Å; N357-A360 PolarHBondContact O-N 2.89Å; A360-M364 WeakPolarHBondContact O-CB 3.03Å; A360-M364 PolarHBondContact O-N 3.38Å; A360-L387 HydrophobicContact CB-CB 4.37Å; A360-A388 HydrophobicContact CB-CB 4.24Å
361	T	90.2	Very high	91.3	Very high	0 Å²	0	16.1 Å²	16.1	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-60.3	-52.8	177.6	-60.7	0	0	0	0	112.6	L45 M46 S112 Q264 N357 S358 T363 M364 E365	L45-T361 HydrophobicContact CD1-CG2 4.17Å; L45-T361 WeakPolarHBondContact CD2-OG1 3.44Å; M46-T361 HydrophobicContact CE-CG2 4.02Å; S112-T361 WeakPolarHBondContact O-CG2 3.47Å; Q264-T361 PolarHBondContact NE2-OG1 3.45Å; N357-T361 PolarHBondContact O-N 3.47Å; N357-T361 PolarHBondContact O-OG1 3.29Å; S358-T361 PolarHBondContact O-N 3.18Å; T361-T363 VanDerWaalsContact C-N 3.34Å; T361-T363 PolarHBondContact O-N 3.06Å; T361-M364 PolarHBondContact O-N 3.35Å; T361-E365 HydrophobicContact CG2-CG 4.26Å; T361-E365 VanDerWaalsContact O-CB 3.3Å; T361-E365 WeakPolarHBondContact O-CB 3.24Å; T361-E365 WeakPolarHBondContact O-CG 3.26Å; T361-E365 PolarHBondContact O-N 3.13Å
362	V	94.7	Very high	91.1	Very high	0 Å²	0	22 Å²	22	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-68.1	-37	-177.1	-60.6	0	0	0	0	111.4	Y115 T131 F134 I135 Q260 S358 L359 D366	Y115-V362 HydrophobicContact CD2-CG1 3.89Å; Y115-V362 HydrophobicContact CE2-CG1 3.94Å; T131-V362 HydrophobicContact CG2-CB 3.92Å; T131-V362 HydrophobicContact CG2-CG2 4.07Å; F134-V362 HydrophobicContact CD1-CG1 4.27Å; F134-V362 HydrophobicContact CD1-CG2 3.91Å; F134-V362 HydrophobicContact CE1-CG1 4.15Å; F134-V362 HydrophobicContact CE1-CG2 3.93Å; I135-V362 HydrophobicContact CD1-CG2 4.2Å; I135-V362 HydrophobicContact CG1-CG2 3.92Å; Q260-V362 HydrophobicContact CB-CG1 4.14Å; Q260-V362 HydrophobicContact CG-CG1 3.58Å; S358-V362 WeakPolarHBondContact O-CG1 3.45Å; S358-V362 WeakPolarHBondContact O-CG2 3.37Å; S358-V362 PolarHBondContact O-N 3.48Å; L359-V362 WeakPolarHBondContact O-CG2 3.46Å; V362-D366 WeakPolarHBondContact O-CA 3.45Å; V362-D366 WeakPolarHBondContact O-CB 3.24Å; V362-D366 VanDerWaalsContact O-CG 3.31Å; V362-D366 PolarHBondContact O-N 3.2Å
363	T	94.5	Very high	90.6	Very high	11 Å²	11	27.6 Å²	27.6	7%	0.067	14%	0.143	C	C	.	.	I	π-helix	trans	-65.6	-44.3	177.3	-54.5	0	0	0	0	110.5	L359 T361 L367 I368 L387 Y391	L359-T363 VanDerWaalsContact O-CB 3.26Å; L359-T363 WeakPolarHBondContact O-CB 3.14Å; L359-T363 PolarHBondContact O-N 3.16Å; L359-T363 PolarHBondContact O-OG1 3.37Å; T361-T363 VanDerWaalsContact C-N 3.34Å; T361-T363 PolarHBondContact O-N 3.06Å; T363-L367 HydrophobicContact CG2-CD1 4.32Å; T363-L367 WeakPolarHBondContact O-CA 3.33Å; T363-L367 WeakPolarHBondContact O-CB 3.25Å; T363-L367 PolarHBondContact O-N 2.89Å; T363-L367 VanDerWaalsContact O-N 3.07Å; T363-I368 HydrophobicContact CG2-CD1 4.38Å; T363-I368 PolarHBondContact O-N 2.81Å; T363-L387 HydrophobicContact CG2-CD1 3.77Å; T363-L387 HydrophobicContact CG2-CD2 3.74Å; T363-L387 HydrophobicContact CG2-CG 4.38Å; T363-Y391 PolarHBondContact OG1-OH 2.71Å
364	M	91	Very high	90.3	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	18%	0.182	C	C	.	.	I	π-helix	trans	-65	-53.4	178	177.2	52.8	96.8	0	0	111.9	A360 T361 I368 K369 M375 A380 V383 S384 L387	A360-M364 WeakPolarHBondContact O-CB 3.03Å; A360-M364 PolarHBondContact O-N 3.38Å; T361-M364 PolarHBondContact O-N 3.35Å; M364-I368 PolarHBondContact O-N 2.69Å; M364-I368 HydrophobicContact SD-CB 4Å; M364-I368 HydrophobicContact SD-CG2 4Å; M364-K369 HydrophobicContact CG-CD 4.34Å; M364-K369 HydrophobicContact CG-CG 4.24Å; M364-K369 WeakPolarHBondContact O-CB 3.3Å; M364-K369 WeakPolarHBondContact O-CG 3.49Å; M364-K369 PolarHBondContact O-N 2.72Å; M364-K369 HydrophobicContact SD-CD 4.47Å; M364-K369 HydrophobicContact SD-CG 3.8Å; M364-M375 HydrophobicContact CE-SD 4.37Å; M364-A380 VanDerWaalsContact CE-CA 3.49Å; M364-A380 HydrophobicContact CE-CB 3.86Å; M364-A380 WeakPolarHBondContact CE-O 3.23Å; M364-V383 HydrophobicContact CE-CB 3.72Å; M364-V383 HydrophobicContact CE-CG1 3.7Å; M364-S384 VanDerWaalsContact CE-OG 3.29Å; M364-S384 WeakPolarHBondContact CE-OG 3.37Å; M364-L387 HydrophobicContact CB-CD1 4.46Å
365	E	90.7	Very high	90.1	Very high	19 Å²	19	35.3 Å²	35.3	9%	0.089	19%	0.193	C	C	.	.	I	π-helix	trans	-72.1	-39.3	-173.9	-69	-66.3	151	0	0	112.8	Q116 R127 T361 K369 P370	Q116-E365 PolarHBondContact NE2-OE2 2.6Å; R127-E365 VanDerWaalsContact NH2-C 3.26Å; R127-E365 PolarHBondContact NH2-O 3.38Å; T361-E365 HydrophobicContact CG2-CG 4.26Å; T361-E365 VanDerWaalsContact O-CB 3.3Å; T361-E365 WeakPolarHBondContact O-CB 3.24Å; T361-E365 WeakPolarHBondContact O-CG 3.26Å; T361-E365 PolarHBondContact O-N 3.13Å; E365-K369 WeakPolarHBondContact OE1-CE 3.42Å; E365-K369 IonicContact OE1-NZ 2.99Å; E365-K369 PolarHBondContact OE1-NZ 3.41Å; E365-K369 IonicContact OE2-NZ 3.42Å; E365-P370 WeakPolarHBondContact O-CD 3.47Å; E365-P370 WeakPolarHBondContact O-CG 3.46Å
366	D	93.9	Very high	89.8	Confident	2 Å²	2	38 Å²	38	1%	0.011	21%	0.211	C	C	.	.	I	π-helix	trans	-97.3	-29.3	-170.8	-51.4	-34.6	0	0	0	113.7	S113 R127 T131 V362	S113-D366 WeakPolarHBondContact CB-OD1 3.39Å; S113-D366 VanDerWaalsContact OG-CG 3.28Å; S113-D366 PolarHBondContact OG-OD1 2.98Å; S113-D366 VanDerWaalsContact OG-OD1 3.07Å; S113-D366 PolarHBondContact OG-OD2 2.95Å; R127-D366 HydrophobicContact CG-CB 4.48Å; R127-D366 IonicContact CZ-OD1 2.76Å; R127-D366 IonicContact NE-OD1 2.8Å; R127-D366 PolarHBondContact NE-OD1 3.15Å; R127-D366 IonicContact NH2-OD1 3.82Å; R127-D366 PolarHBondContact NH2-OD1 3.23Å; T131-D366 HydrophobicContact CG2-CB 3.95Å; T131-D366 PolarHBondContact OG1-OD2 3.37Å; V362-D366 WeakPolarHBondContact O-CA 3.45Å; V362-D366 WeakPolarHBondContact O-CB 3.24Å; V362-D366 VanDerWaalsContact O-CG 3.31Å; V362-D366 PolarHBondContact O-N 3.2Å
367	L	93.5	Very high	89.5	Confident	46 Å²	46	42.1 Å²	42.1	24%	0.241	23%	0.231	C	C	.	.	I	π-helix	trans	-110.6	-39.4	-174.6	-53.7	-178.3	0	0	0	113	I128 T131 L132 I135 T363 H371	I128-L367 HydrophobicContact CG2-CD2 4.38Å; T131-L367 HydrophobicContact CG2-CG 4.48Å; L132-L367 HydrophobicContact CD2-CD1 4.3Å; I135-L367 HydrophobicContact CD1-CD1 4.06Å; T363-L367 HydrophobicContact CG2-CD1 4.32Å; T363-L367 WeakPolarHBondContact O-CA 3.33Å; T363-L367 WeakPolarHBondContact O-CB 3.25Å; T363-L367 PolarHBondContact O-N 2.89Å; T363-L367 VanDerWaalsContact O-N 3.07Å; L367-H371 PolarHBondContact O-ND1 3.49Å
368	I	92.5	Very high	89.1	Confident	32 Å²	32	49 Å²	49	16%	0.164	26%	0.263	C	S	.	.	I	π-helix	trans	-91.4	-60.3	-173.7	-60.5	-178.7	0	0	0	112.3	T363 M364 P370 H371 F372 M375 V383 L387	T363-I368 HydrophobicContact CG2-CD1 4.38Å; T363-I368 PolarHBondContact O-N 2.81Å; M364-I368 PolarHBondContact O-N 2.69Å; M364-I368 HydrophobicContact SD-CB 4Å; M364-I368 HydrophobicContact SD-CG2 4Å; I368-P370 VanDerWaalsContact C-N 3.29Å; I368-H371 PolarHBondContact O-N 3.15Å; I368-F372 HydrophobicContact CG2-CD2 4.11Å; I368-F372 PolarHBondContact O-N 3.4Å; I368-M375 HydrophobicContact CG2-CE 3.69Å; I368-V383 HydrophobicContact CD1-CG1 3.58Å; I368-L387 HydrophobicContact CD1-CD1 3.7Å; I368-L387 HydrophobicContact CD1-CD2 4.34Å; I368-L387 HydrophobicContact CD1-CG 4.39Å
369	K	88.6	Confident	88.8	Confident	54 Å²	54	57.4 Å²	57.4	24%	0.235	29%	0.294	C	S	.	.	T	Hydrogen-bonded Turn	trans	-51.6	-39.6	-177.3	-78.1	-175.7	176.1	-177.6	0	113.8	M364 E365 H371 F372	M364-K369 HydrophobicContact CG-CD 4.34Å; M364-K369 HydrophobicContact CG-CG 4.24Å; M364-K369 WeakPolarHBondContact O-CB 3.3Å; M364-K369 WeakPolarHBondContact O-CG 3.49Å; M364-K369 PolarHBondContact O-N 2.72Å; M364-K369 HydrophobicContact SD-CD 4.47Å; M364-K369 HydrophobicContact SD-CG 3.8Å; E365-K369 WeakPolarHBondContact OE1-CE 3.42Å; E365-K369 IonicContact OE1-NZ 2.99Å; E365-K369 PolarHBondContact OE1-NZ 3.41Å; E365-K369 IonicContact OE2-NZ 3.42Å; K369-H371 PolarHBondContact O-N 3.26Å; K369-F372 CarbonylContact O-C 3.55Å; K369-F372 VanDerWaalsContact O-C 3.24Å; K369-F372 PolarHBondContact O-N 3.33Å
370	P	88.7	Confident	88.3	Confident	44 Å²	44	57.5 Å²	57.5	29%	0.286	30%	0.296	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.8	-20.7	178.6	-25.9	38.1	0	0	0	114.7	E365 I368	E365-P370 WeakPolarHBondContact O-CD 3.47Å; E365-P370 WeakPolarHBondContact O-CG 3.46Å; I368-P370 VanDerWaalsContact C-N 3.29Å
371	H	89.3	Confident	87.7	Confident	120 Å²	120	58 Å²	58	56%	0.556	30%	0.298	S	S	*	.	T	Hydrogen-bonded Turn	trans	-98.8	-19.3	176.1	-61.9	96.6	0	0	0	112.4	L367 I368 K369	L367-H371 PolarHBondContact O-ND1 3.49Å; I368-H371 PolarHBondContact O-N 3.15Å; K369-H371 PolarHBondContact O-N 3.26Å
372	F	89.6	Confident	87.6	Confident	128 Å²	128	63.8 Å²	63.8	56%	0.561	33%	0.329	S	S	*	.			trans	-130.8	65.4	-179.7	-60.3	-80	0	0	0	111.7	I368 K369 S374 M375	I368-F372 HydrophobicContact CG2-CD2 4.11Å; I368-F372 PolarHBondContact O-N 3.4Å; K369-F372 CarbonylContact O-C 3.55Å; K369-F372 VanDerWaalsContact O-C 3.24Å; K369-F372 PolarHBondContact O-N 3.33Å; F372-S374 VanDerWaalsContact C-N 3.26Å; F372-S374 PolarHBondContact O-N 3.06Å; F372-M375 HydrophobicContact CB-CE 3.73Å; F372-M375 HydrophobicContact CG-CE 4.28Å; F372-M375 WeakPolarHBondContact O-CB 3.48Å; F372-M375 PolarHBondContact O-N 3.1Å
373	P	79.9	Confident	87.2	Confident	116 Å²	116	66 Å²	66	75%	0.753	34%	0.342	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.6	-21.4	-172.9	26.7	-35	0	0	0	114.1
374	S	83.3	Confident	86.6	Confident	118 Å²	118	65.5 Å²	65.5	83%	0.825	34%	0.339	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.4	15.3	179.9	54.8	0	0	0	0	113.9	F372 S376	F372-S374 VanDerWaalsContact C-N 3.26Å; F372-S374 PolarHBondContact O-N 3.06Å; S374-S376 PolarHBondContact O-N 3.4Å
375	M	86.8	Confident	86.2	Confident	47 Å²	47	68 Å²	68	23%	0.232	35%	0.35	C	S	.	.			trans	-66.8	131.3	178.6	-170.1	179.5	-56.7	0	0	111	M364 I368 F372 R379 A380 V383	M364-M375 HydrophobicContact CE-SD 4.37Å; I368-M375 HydrophobicContact CG2-CE 3.69Å; F372-M375 HydrophobicContact CB-CE 3.73Å; F372-M375 HydrophobicContact CG-CE 4.28Å; F372-M375 WeakPolarHBondContact O-CB 3.48Å; F372-M375 PolarHBondContact O-N 3.1Å; M375-R379 HydrophobicContact CG-CB 3.81Å; M375-R379 HydrophobicContact SD-CB 4.3Å; M375-A380 HydrophobicContact CG-CB 4.27Å; M375-A380 WeakPolarHBondContact SD-CA 2.93Å; M375-A380 HydrophobicContact SD-CB 3.85Å; M375-V383 HydrophobicContact SD-CG2 4.42Å
376	S	85.9	Confident	86.1	Confident	56 Å²	56	70 Å²	70	39%	0.392	37%	0.369	S	S	.	.			trans	-65.9	149.7	173.5	65.7	0	0	0	0	111.5	S374 E378 R379 A380	S374-S376 PolarHBondContact O-N 3.4Å; S376-E378 PolarHBondContact O-N 3.15Å; S376-R379 PolarHBondContact O-N 2.81Å; S376-R379 VanDerWaalsContact O-N 3.08Å; S376-R379 WeakPolarHBondContact OG-CG 3.46Å; S376-R379 PolarHBondContact OG-N 3.46Å; S376-A380 PolarHBondContact O-N 2.97Å
377	E	80.9	Confident	85.8	Confident	88 Å²	88	71.1 Å²	71.1	41%	0.411	38%	0.375	S	S	.	.	H	α-helix	trans	-56.7	-34.8	179.5	-75.6	-64.5	149.3	0	0	113.1	T41 A380 T381	T41-E377 WeakPolarHBondContact CB-OE2 3.24Å; T41-E377 PolarHBondContact N-OE2 3.4Å; T41-E377 PolarHBondContact OG1-OE2 3.45Å; E377-A380 PolarHBondContact O-N 3.41Å; E377-T381 WeakPolarHBondContact O-CB 3.45Å; E377-T381 PolarHBondContact O-N 3.47Å; E377-T381 PolarHBondContact O-OG1 3.36Å
378	E	81.5	Confident	85.1	Confident	148 Å²	148	69 Å²	69	69%	0.692	36%	0.364	S	S	*	.	H	α-helix	trans	-65.5	-45.7	176.1	-64	-179.6	171.9	0	0	111.8	S376 T381 L382	S376-E378 PolarHBondContact O-N 3.15Å; E378-T381 PolarHBondContact O-N 3.48Å; E378-L382 WeakPolarHBondContact O-CB 3.39Å; E378-L382 PolarHBondContact O-N 2.59Å
379	R	85.4	Confident	84.6	Confident	175 Å²	175	70.3 Å²	70.3	66%	0.66	37%	0.374	S	S	*	.	H	α-helix	trans	-67.7	-39.5	177.3	-68.8	179.6	95.2	-174.2	7	110.8	M375 S376 T381 L382 V383	M375-R379 HydrophobicContact CG-CB 3.81Å; M375-R379 HydrophobicContact SD-CB 4.3Å; S376-R379 PolarHBondContact O-N 2.81Å; S376-R379 VanDerWaalsContact O-N 3.08Å; S376-R379 WeakPolarHBondContact OG-CG 3.46Å; S376-R379 PolarHBondContact OG-N 3.46Å; R379-T381 VanDerWaalsContact C-N 3.33Å; R379-T381 PolarHBondContact O-N 2.85Å; R379-L382 PolarHBondContact O-N 3.16Å; R379-V383 WeakPolarHBondContact O-CB 3.48Å; R379-V383 VanDerWaalsContact O-CG2 3.28Å; R379-V383 WeakPolarHBondContact O-CG2 3.39Å; R379-V383 PolarHBondContact O-N 3.01Å
380	A	82	Confident	84.5	Confident	3 Å²	3	70.5 Å²	70.5	3%	0.025	38%	0.382	C	S	.	.	H	α-helix	trans	-62	-42.6	175.5	0	0	0	0	0	111.5	T41 M364 M375 S376 E377 V383 S384	T41-A380 WeakPolarHBondContact OG1-CB 3.46Å; M364-A380 VanDerWaalsContact CE-CA 3.49Å; M364-A380 HydrophobicContact CE-CB 3.86Å; M364-A380 WeakPolarHBondContact CE-O 3.23Å; M375-A380 HydrophobicContact CG-CB 4.27Å; M375-A380 WeakPolarHBondContact SD-CA 2.93Å; M375-A380 HydrophobicContact SD-CB 3.85Å; S376-A380 PolarHBondContact O-N 2.97Å; E377-A380 PolarHBondContact O-N 3.41Å; A380-V383 PolarHBondContact O-N 2.86Å; A380-S384 WeakPolarHBondContact O-CB 3.37Å; A380-S384 PolarHBondContact O-N 2.94Å; A380-S384 PolarHBondContact O-OG 2.04Å
381	T	80.1	Confident	84.5	Confident	10 Å²	10	69.5 Å²	69.5	6%	0.061	37%	0.373	C	S	.	.	H	α-helix	trans	-63.9	-44.8	175.4	-57.7	0	0	0	0	111.2	E377 E378 R379 V383 S384 K385	E377-T381 WeakPolarHBondContact O-CB 3.45Å; E377-T381 PolarHBondContact O-N 3.47Å; E377-T381 PolarHBondContact O-OG1 3.36Å; E378-T381 PolarHBondContact O-N 3.48Å; R379-T381 VanDerWaalsContact C-N 3.33Å; R379-T381 PolarHBondContact O-N 2.85Å; T381-V383 PolarHBondContact O-N 3.34Å; T381-S384 WeakPolarHBondContact O-CB 3.36Å; T381-S384 PolarHBondContact O-N 3.14Å; T381-K385 WeakPolarHBondContact O-CG 3.29Å; T381-K385 PolarHBondContact O-N 3.12Å
382	L	86.1	Confident	84.1	Confident	123 Å²	123	63.9 Å²	63.9	64%	0.644	35%	0.348	S	S	*	.	H	α-helix	trans	-60.5	-45.5	177.5	-174.4	71.3	0	0	0	112.2	E378 R379 S384 K385 A386	E378-L382 WeakPolarHBondContact O-CB 3.39Å; E378-L382 PolarHBondContact O-N 2.59Å; R379-L382 PolarHBondContact O-N 3.16Å; L382-S384 VanDerWaalsContact C-N 3.34Å; L382-S384 PolarHBondContact O-N 3.24Å; L382-K385 PolarHBondContact O-N 3.01Å; L382-A386 PolarHBondContact O-N 2.9Å
383	V	87.9	Confident	83.7	Confident	47 Å²	47	63.5 Å²	63.5	29%	0.285	35%	0.351	S	S	.	.	H	α-helix	trans	-63.2	-41.6	176.6	170.1	0	0	0	0	110.6	M364 I368 M375 R379 A380 T381 K385 A386 L387	M364-V383 HydrophobicContact CE-CB 3.72Å; M364-V383 HydrophobicContact CE-CG1 3.7Å; I368-V383 HydrophobicContact CD1-CG1 3.58Å; M375-V383 HydrophobicContact SD-CG2 4.42Å; R379-V383 WeakPolarHBondContact O-CB 3.48Å; R379-V383 VanDerWaalsContact O-CG2 3.28Å; R379-V383 WeakPolarHBondContact O-CG2 3.39Å; R379-V383 PolarHBondContact O-N 3.01Å; A380-V383 PolarHBondContact O-N 2.86Å; T381-V383 PolarHBondContact O-N 3.34Å; V383-K385 VanDerWaalsContact C-N 3.29Å; V383-K385 PolarHBondContact O-N 3.42Å; V383-A386 PolarHBondContact O-N 3.25Å; V383-L387 HydrophobicContact CG1-CD1 4.15Å; V383-L387 HydrophobicContact CG1-CG 4.33Å; V383-L387 VanDerWaalsContact O-CG 3.28Å; V383-L387 WeakPolarHBondContact O-CG 3.46Å; V383-L387 PolarHBondContact O-N 3.23Å
384	S	81.7	Confident	84	Confident	0 Å²	0	61.6 Å²	61.6	0%	0	33%	0.334	C	S	.	.	H	α-helix	trans	-60.6	-39.3	176.4	-58.3	0	0	0	0	112	M364 A380 T381 L382 A388	M364-S384 VanDerWaalsContact CE-OG 3.29Å; M364-S384 WeakPolarHBondContact CE-OG 3.37Å; A380-S384 WeakPolarHBondContact O-CB 3.37Å; A380-S384 PolarHBondContact O-N 2.94Å; A380-S384 PolarHBondContact O-OG 2.04Å; T381-S384 WeakPolarHBondContact O-CB 3.36Å; T381-S384 PolarHBondContact O-N 3.14Å; L382-S384 VanDerWaalsContact C-N 3.34Å; L382-S384 PolarHBondContact O-N 3.24Å; S384-A388 PolarHBondContact O-N 2.91Å; S384-A388 VanDerWaalsContact O-N 3.11Å
385	K	82.6	Confident	83.9	Confident	52 Å²	52	56 Å²	56	23%	0.226	30%	0.295	C	S	.	.	H	α-helix	trans	-65.7	-45.4	173.6	-68.1	-176.5	178.8	-168.8	0	111.5	F44 T177 T381 L382 V383 L387 A388 T389	F44-K385 HydrophobicContact CE2-CG 4.29Å; F44-K385 HydrophobicContact CZ-CG 4.03Å; T177-K385 WeakPolarHBondContact O-CD 3.49Å; T177-K385 WeakPolarHBondContact O-CE 3.28Å; T177-K385 WeakPolarHBondContact O-CG 3.39Å; T381-K385 WeakPolarHBondContact O-CG 3.29Å; T381-K385 PolarHBondContact O-N 3.12Å; L382-K385 PolarHBondContact O-N 3.01Å; V383-K385 VanDerWaalsContact C-N 3.29Å; V383-K385 PolarHBondContact O-N 3.42Å; K385-L387 VanDerWaalsContact C-N 3.32Å; K385-L387 PolarHBondContact O-N 2.79Å; K385-A388 PolarHBondContact O-N 3.34Å; K385-T389 PolarHBondContact O-N 3.42Å; K385-T389 VanDerWaalsContact O-N 3.07Å; K385-T389 PolarHBondContact O-OG1 3.21Å
386	A	87.4	Confident	83.6	Confident	60 Å²	60	55.6 Å²	55.6	50%	0.496	29%	0.293	S	S	.	.	H	α-helix	trans	-61.1	-39.6	176.8	0	0	0	0	0	112.5	L382 V383 T389 S390	L382-A386 PolarHBondContact O-N 2.9Å; V383-A386 PolarHBondContact O-N 3.25Å; A386-T389 WeakPolarHBondContact O-CB 3.31Å; A386-T389 PolarHBondContact O-N 3.07Å; A386-S390 PolarHBondContact O-N 3.41Å
387	L	87.3	Confident	83.4	Confident	27 Å²	27	55.6 Å²	55.6	14%	0.141	30%	0.297	C	S	.	.	H	α-helix	trans	-62.3	-48.8	175.5	-72.4	171.4	0	0	0	111.8	A360 T363 M364 I368 V383 K385 T389 S390 Y391	A360-L387 HydrophobicContact CB-CB 4.37Å; T363-L387 HydrophobicContact CG2-CD1 3.77Å; T363-L387 HydrophobicContact CG2-CD2 3.74Å; T363-L387 HydrophobicContact CG2-CG 4.38Å; M364-L387 HydrophobicContact CB-CD1 4.46Å; I368-L387 HydrophobicContact CD1-CD1 3.7Å; I368-L387 HydrophobicContact CD1-CD2 4.34Å; I368-L387 HydrophobicContact CD1-CG 4.39Å; V383-L387 HydrophobicContact CG1-CD1 4.15Å; V383-L387 HydrophobicContact CG1-CG 4.33Å; V383-L387 VanDerWaalsContact O-CG 3.28Å; V383-L387 WeakPolarHBondContact O-CG 3.46Å; V383-L387 PolarHBondContact O-N 3.23Å; K385-L387 VanDerWaalsContact C-N 3.32Å; K385-L387 PolarHBondContact O-N 2.79Å; L387-T389 PolarHBondContact O-N 3.35Å; L387-S390 WeakPolarHBondContact CA-OG 3.2Å; L387-S390 PolarHBondContact O-N 3.22Å; L387-S390 VanDerWaalsContact O-N 3.07Å; L387-S390 PolarHBondContact O-OG 3.37Å; L387-Y391 WeakPolarHBondContact O-CD2 3.3Å; L387-Y391 PolarHBondContact O-N 3.04Å
388	A	79.4	Confident	83.7	Confident	1 Å²	1	53 Å²	53	1%	0.008	29%	0.285	C	S	.	.	H	α-helix	trans	-57.3	-39.5	176.5	0	0	0	0	0	111.5	T177 A360 S384 K385 G392	T177-A388 HydrophobicContact CG2-CB 3.69Å; A360-A388 HydrophobicContact CB-CB 4.24Å; S384-A388 PolarHBondContact O-N 2.91Å; S384-A388 VanDerWaalsContact O-N 3.11Å; K385-A388 PolarHBondContact O-N 3.34Å; A388-G392 PolarHBondContact O-N 2.66Å; A388-G392 VanDerWaalsContact O-N 3.09Å
389	T	82.5	Confident	83.9	Confident	60 Å²	60	46 Å²	46	37%	0.368	25%	0.252	S	S	.	.	H	α-helix	trans	-63.7	-43.9	172.8	-54.1	0	0	0	0	113	T173 T177 K385 A386 L387 Y391 G392 L393	T173-T389 HydrophobicContact CG2-CG2 4.06Å; T177-T389 WeakPolarHBondContact CG2-OG1 3.46Å; K385-T389 PolarHBondContact O-N 3.42Å; K385-T389 VanDerWaalsContact O-N 3.07Å; K385-T389 PolarHBondContact O-OG1 3.21Å; A386-T389 WeakPolarHBondContact O-CB 3.31Å; A386-T389 PolarHBondContact O-N 3.07Å; L387-T389 PolarHBondContact O-N 3.35Å; T389-Y391 VanDerWaalsContact C-N 3.35Å; T389-Y391 PolarHBondContact O-N 2.76Å; T389-G392 WeakPolarHBondContact O-CA 3.27Å; T389-G392 PolarHBondContact O-N 2.54Å; T389-G392 VanDerWaalsContact O-N 3.14Å; T389-L393 PolarHBondContact O-N 2.83Å; T389-L393 VanDerWaalsContact O-N 3.15Å
390	S	87.1	Confident	83.8	Confident	57 Å²	57	43.5 Å²	43.5	40%	0.399	24%	0.244	S	C	.	.	H	α-helix	trans	-63.1	-39.9	179.4	73	0	0	0	0	112.6	A386 L387 G392 L393 L394	A386-S390 PolarHBondContact O-N 3.41Å; L387-S390 WeakPolarHBondContact CA-OG 3.2Å; L387-S390 PolarHBondContact O-N 3.22Å; L387-S390 VanDerWaalsContact O-N 3.07Å; L387-S390 PolarHBondContact O-OG 3.37Å; S390-G392 VanDerWaalsContact C-N 3.32Å; S390-G392 PolarHBondContact O-N 3.25Å; S390-L393 PolarHBondContact O-N 3.23Å; S390-L394 PolarHBondContact O-N 3.48Å
391	Y	87.2	Confident	83.8	Confident	23 Å²	23	47.6 Å²	47.6	9%	0.09	27%	0.265	C	S	.	.	H	α-helix	trans	-66.7	-35	174.3	-76.1	-63	0	0	0	111.6	I135 V139 L359 T363 L387 T389 L393 L394 C395	I135-Y391 HydrophobicContact CG2-CE1 3.97Å; V139-Y391 HydrophobicContact CG2-CD1 3.97Å; V139-Y391 HydrophobicContact CG2-CE1 4.03Å; L359-Y391 HydrophobicContact CB-CD1 4.47Å; L359-Y391 HydrophobicContact CB-CD2 3.74Å; L359-Y391 HydrophobicContact CB-CE2 3.78Å; L359-Y391 HydrophobicContact CB-CG 4.11Å; L359-Y391 HydrophobicContact CD1-CD1 3.95Å; L359-Y391 HydrophobicContact CD1-CD2 4.5Å; L359-Y391 HydrophobicContact CD1-CE1 4.4Å; L359-Y391 HydrophobicContact CD1-CG 4.01Å; L359-Y391 HydrophobicContact CD2-CE1 4.22Å; T363-Y391 PolarHBondContact OG1-OH 2.71Å; L387-Y391 WeakPolarHBondContact O-CD2 3.3Å; L387-Y391 PolarHBondContact O-N 3.04Å; T389-Y391 VanDerWaalsContact C-N 3.35Å; T389-Y391 PolarHBondContact O-N 2.76Å; Y391-L393 PolarHBondContact O-N 3.34Å; Y391-L394 HydrophobicContact CD1-CD2 4.29Å; Y391-L394 PolarHBondContact O-N 2.95Å; Y391-C395 WeakPolarHBondContact O-CB 3.24Å; Y391-C395 PolarHBondContact O-N 3.07Å; Y391-C395 PolarHBondContact O-SG 3.22Å
392	G	80.8	Confident	83.8	Confident	3 Å²	3	47.6 Å²	47.6	3%	0.031	27%	0.265	C	S	.	.	H	α-helix	trans	-53.8	-49.1	170.2	0	0	0	0	0	113	F356 A388 T389 S390 C395 L396	F356-G392 VanDerWaalsContact CZ-CA 3.48Å; A388-G392 PolarHBondContact O-N 2.66Å; A388-G392 VanDerWaalsContact O-N 3.09Å; T389-G392 WeakPolarHBondContact O-CA 3.27Å; T389-G392 PolarHBondContact O-N 2.54Å; T389-G392 VanDerWaalsContact O-N 3.14Å; S390-G392 VanDerWaalsContact C-N 3.32Å; S390-G392 PolarHBondContact O-N 3.25Å; G392-C395 PolarHBondContact O-N 3.2Å; G392-L396 PolarHBondContact O-N 3.19Å
393	L	81.7	Confident	83.5	Confident	119 Å²	119	45.7 Å²	45.7	62%	0.623	25%	0.253	S	S	*	.	H	α-helix	trans	-65.1	-42.3	177.2	-65.9	174.9	0	0	0	112.5	T389 S390 Y391 C395 L396	T389-L393 PolarHBondContact O-N 2.83Å; T389-L393 VanDerWaalsContact O-N 3.15Å; S390-L393 PolarHBondContact O-N 3.23Å; Y391-L393 PolarHBondContact O-N 3.34Å; L393-C395 VanDerWaalsContact C-N 3.28Å; L393-C395 PolarHBondContact O-N 3.09Å; L393-L396 HydrophobicContact CD2-CD1 4.25Å; L393-L396 WeakPolarHBondContact O-CB 3.29Å; L393-L396 PolarHBondContact O-N 3.02Å
394	L	85.9	Confident	83	Confident	77 Å²	77	48.5 Å²	48.5	40%	0.403	27%	0.265	S	S	.	.	H	α-helix	trans	-62.3	-36.3	177.9	-175.8	60.5	0	0	0	112.1	V139 S390 Y391 L396 A397 M398	V139-L394 HydrophobicContact CB-CD2 4.48Å; V139-L394 HydrophobicContact CG1-CD2 3.7Å; V139-L394 HydrophobicContact CG1-CG 3.89Å; V139-L394 HydrophobicContact CG2-CD2 3.87Å; S390-L394 PolarHBondContact O-N 3.48Å; Y391-L394 HydrophobicContact CD1-CD2 4.29Å; Y391-L394 PolarHBondContact O-N 2.95Å; L394-L396 VanDerWaalsContact C-N 3.29Å; L394-L396 PolarHBondContact O-N 3.19Å; L394-A397 WeakPolarHBondContact O-CB 3.2Å; L394-A397 PolarHBondContact O-N 3.32Å; L394-M398 PolarHBondContact O-N 3.49Å; L394-M398 VanDerWaalsContact O-N 3.16Å
395	C	80.8	Confident	82.4	Confident	1 Å²	1	52 Å²	52	1%	0.007	28%	0.283	C	S	.	.	H	α-helix	trans	-67.1	-29.9	178.7	-67.6	0	0	0	0	112.9	M142 F356 Y391 G392 L393 A397 M398 A399	M142-C395 HydrophobicContact CB-CB 4.12Å; M142-C395 WeakPolarHBondContact CB-SG 3.29Å; F356-C395 HydrophobicContact CE1-CB 4.29Å; F356-C395 VanDerWaalsContact CE1-SG 3.51Å; F356-C395 HydrophobicContact CZ-CB 4.25Å; Y391-C395 WeakPolarHBondContact O-CB 3.24Å; Y391-C395 PolarHBondContact O-N 3.07Å; Y391-C395 PolarHBondContact O-SG 3.22Å; G392-C395 PolarHBondContact O-N 3.2Å; L393-C395 VanDerWaalsContact C-N 3.28Å; L393-C395 PolarHBondContact O-N 3.09Å; C395-A397 VanDerWaalsContact C-N 3.32Å; C395-A397 PolarHBondContact O-N 2.72Å; C395-M398 PolarHBondContact O-N 2.97Å; C395-A399 PolarHBondContact O-N 3.45Å
396	L	81	Confident	81.6	Confident	37 Å²	37	51.6 Å²	51.6	19%	0.194	29%	0.293	C	S	.	.	H	α-helix	trans	-62.7	-40.5	173.2	-63.1	169.8	0	0	0	111.2	V165 L166 G392 L393 L394 A399	V165-L396 HydrophobicContact CG1-CD2 3.57Å; V165-L396 WeakPolarHBondContact O-CD2 3.46Å; L166-L396 HydrophobicContact CD2-CD1 3.71Å; L166-L396 HydrophobicContact CD2-CD2 4.18Å; G392-L396 PolarHBondContact O-N 3.19Å; L393-L396 HydrophobicContact CD2-CD1 4.25Å; L393-L396 WeakPolarHBondContact O-CB 3.29Å; L393-L396 PolarHBondContact O-N 3.02Å; L394-L396 VanDerWaalsContact C-N 3.29Å; L394-L396 PolarHBondContact O-N 3.19Å; L396-A399 PolarHBondContact O-N 2.89Å
397	A	82.8	Confident	80.7	Confident	57 Å²	57	50.7 Å²	50.7	47%	0.471	28%	0.28	S	S	.	.	H	α-helix	trans	-65.3	-40.4	174.5	0	0	0	0	0	111.7	L394 C395 A399 Y400	L394-A397 WeakPolarHBondContact O-CB 3.2Å; L394-A397 PolarHBondContact O-N 3.32Å; C395-A397 VanDerWaalsContact C-N 3.32Å; C395-A397 PolarHBondContact O-N 2.72Å; A397-A399 VanDerWaalsContact C-N 3.34Å; A397-A399 PolarHBondContact O-N 2.76Å; A397-Y400 WeakPolarHBondContact O-CB 3.42Å; A397-Y400 PolarHBondContact O-N 3.43Å
398	M	86.7	Confident	80.3	Confident	33 Å²	33	49.6 Å²	49.6	16%	0.163	27%	0.274	C	S	.	.	H	α-helix	trans	-69.4	-28.6	178.1	-64.7	-53	-54.9	0	0	113.8	V139 I140 L394 C395 Y400 L401 T402	V139-M398 HydrophobicContact CG1-CG 3.67Å; V139-M398 HydrophobicContact CG1-SD 4.32Å; I140-M398 HydrophobicContact CB-CE 4.32Å; I140-M398 HydrophobicContact CG1-CE 3.88Å; I140-M398 HydrophobicContact CG2-CE 4.38Å; L394-M398 PolarHBondContact O-N 3.49Å; L394-M398 VanDerWaalsContact O-N 3.16Å; C395-M398 PolarHBondContact O-N 2.97Å; M398-Y400 PolarHBondContact O-N 2.99Å; M398-L401 HydrophobicContact CE-CD1 3.67Å; M398-L401 PolarHBondContact O-N 3.16Å; M398-L401 HydrophobicContact SD-CD1 3.84Å; M398-T402 PolarHBondContact O-N 2.97Å; M398-T402 VanDerWaalsContact O-N 3.08Å; M398-T402 PolarHBondContact O-OG1 3.43Å; M398-T402 VanDerWaalsContact O-OG1 3.12Å
399	A	85.4	Confident	80.6	Confident	0 Å²	0	50 Å²	50	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-61.8	-33.6	173	0	0	0	0	0	111.5	V146 V165 C395 L396 A397 T402 H403	V146-A399 HydrophobicContact CB-CB 4.49Å; V146-A399 HydrophobicContact CG1-CB 4.45Å; V165-A399 HydrophobicContact CG1-CB 4.09Å; C395-A399 PolarHBondContact O-N 3.45Å; L396-A399 PolarHBondContact O-N 2.89Å; A397-A399 VanDerWaalsContact C-N 3.34Å; A397-A399 PolarHBondContact O-N 2.76Å; A399-T402 WeakPolarHBondContact O-CB 3.36Å; A399-T402 PolarHBondContact O-N 3.43Å; A399-H403 PolarHBondContact O-N 2.89Å
400	Y	82.5	Confident	80.8	Confident	124 Å²	124	47.5 Å²	47.5	49%	0.486	26%	0.261	S	S	.	.	H	α-helix	trans	-64.8	-43.7	173.4	-176.1	-89.5	0	0	0	113.1	W162 A397 M398 T402 H403 L404	W162-Y400 AromaticContact CH2-CD2 3.33Å; W162-Y400 HydrophobicContact CH2-CD2 3.33Å; W162-Y400 HydrophobicContact CH2-CE2 4.27Å; W162-Y400 HydrophobicContact CH2-CG 4Å; W162-Y400 AromaticContact CZ2-CD2 3.52Å; W162-Y400 HydrophobicContact CZ2-CD2 3.52Å; W162-Y400 HydrophobicContact CZ2-CE2 4.02Å; W162-Y400 HydrophobicContact CZ3-CD2 4.1Å; A397-Y400 WeakPolarHBondContact O-CB 3.42Å; A397-Y400 PolarHBondContact O-N 3.43Å; M398-Y400 PolarHBondContact O-N 2.99Å; Y400-T402 VanDerWaalsContact C-N 3.28Å; Y400-T402 PolarHBondContact O-N 2.88Å; Y400-H403 WeakPolarHBondContact O-CB 3.37Å; Y400-H403 PolarHBondContact O-N 3.39Å; Y400-L404 HydrophobicContact CD1-CD1 4.3Å; Y400-L404 HydrophobicContact CE1-CD1 3.88Å; Y400-L404 HydrophobicContact CE1-CG 4.41Å
401	L	82.7	Confident	80.8	Confident	88 Å²	88	45.5 Å²	45.5	46%	0.461	25%	0.246	S	C	.	.	H	α-helix	trans	-63.2	-37.2	175.8	-66	177.5	0	0	0	112	M398 H403 L404 M405	M398-L401 HydrophobicContact CE-CD1 3.67Å; M398-L401 PolarHBondContact O-N 3.16Å; M398-L401 HydrophobicContact SD-CD1 3.84Å; L401-H403 VanDerWaalsContact C-N 3.32Å; L401-H403 PolarHBondContact O-N 3.1Å; L401-L404 HydrophobicContact CD2-CD1 4.45Å; L401-L404 WeakPolarHBondContact O-CB 3.34Å; L401-L404 PolarHBondContact O-N 2.71Å; L401-L404 VanDerWaalsContact O-N 3.17Å; L401-M405 WeakPolarHBondContact O-CG 3.15Å
402	T	79.8	Confident	80.8	Confident	11 Å²	11	44.7 Å²	44.7	7%	0.067	24%	0.243	C	C	.	.	H	α-helix	trans	-60.5	-42.5	176.6	-56.8	0	0	0	0	111.6	V144 Y147 M398 A399 Y400 L404 M405	V144-T402 HydrophobicContact CB-CG2 4.24Å; V144-T402 HydrophobicContact CG1-CG2 4.24Å; V144-T402 HydrophobicContact CG2-CG2 3.99Å; V144-T402 PolarHBondContact N-OG1 3.37Å; Y147-T402 HydrophobicContact CD1-CG2 3.74Å; Y147-T402 HydrophobicContact CE1-CG2 4.45Å; Y147-T402 HydrophobicContact CG-CG2 4.06Å; M398-T402 PolarHBondContact O-N 2.97Å; M398-T402 VanDerWaalsContact O-N 3.08Å; M398-T402 PolarHBondContact O-OG1 3.43Å; M398-T402 VanDerWaalsContact O-OG1 3.12Å; A399-T402 WeakPolarHBondContact O-CB 3.36Å; A399-T402 PolarHBondContact O-N 3.43Å; Y400-T402 VanDerWaalsContact C-N 3.28Å; Y400-T402 PolarHBondContact O-N 2.88Å; T402-L404 PolarHBondContact O-N 3.3Å; T402-L404 VanDerWaalsContact O-N 3.12Å; T402-M405 PolarHBondContact O-N 2.86Å; T402-M405 VanDerWaalsContact O-N 3.07Å
403	H	80	Confident	81.3	Confident	83 Å²	83	44.9 Å²	44.9	38%	0.384	24%	0.244	S	C	.	.	H	α-helix	trans	-55.7	-30.7	178.4	176.2	47.4	0	0	0	112.8	Y147 A399 Y400 L401	Y147-H403 HydrophobicContact CD2-CB 4.17Å; Y147-H403 HydrophobicContact CE2-CB 3.67Å; Y147-H403 AromaticContact CE2-ND1 3.82Å; Y147-H403 AromaticContact CZ-ND1 3.91Å; Y147-H403 PolarHBondContact OH-ND1 2.88Å; A399-H403 PolarHBondContact O-N 2.89Å; Y400-H403 WeakPolarHBondContact O-CB 3.37Å; Y400-H403 PolarHBondContact O-N 3.39Å; L401-H403 VanDerWaalsContact C-N 3.32Å; L401-H403 PolarHBondContact O-N 3.1Å
404	L	77.4	Confident	81.8	Confident	106 Å²	106	39.9 Å²	39.9	56%	0.555	22%	0.218	S	C	*	.	H	α-helix	trans	-79.8	-16.8	-178.8	-58.5	175.9	0	0	0	114.1	Y400 L401 T402 G406	Y400-L404 HydrophobicContact CD1-CD1 4.3Å; Y400-L404 HydrophobicContact CE1-CD1 3.88Å; Y400-L404 HydrophobicContact CE1-CG 4.41Å; L401-L404 HydrophobicContact CD2-CD1 4.45Å; L401-L404 WeakPolarHBondContact O-CB 3.34Å; L401-L404 PolarHBondContact O-N 2.71Å; L401-L404 VanDerWaalsContact O-N 3.17Å; T402-L404 PolarHBondContact O-N 3.3Å; T402-L404 VanDerWaalsContact O-N 3.12Å; L404-G406 VanDerWaalsContact C-N 3.34Å; L404-G406 PolarHBondContact O-N 2.85Å
405	M	69.7	Low	82.1	Confident	74 Å²	74	37.5 Å²	37.5	37%	0.365	20%	0.204	S	C	.	.	S	Bend	trans	-73.5	-20.1	-167.2	-65.3	-179.2	75.1	0	0	114.2	L401 T402 D407 V412 R464	L401-M405 WeakPolarHBondContact O-CG 3.15Å; T402-M405 PolarHBondContact O-N 2.86Å; T402-M405 VanDerWaalsContact O-N 3.07Å; M405-D407 PolarHBondContact O-N 2.99Å; M405-V412 HydrophobicContact CB-CG2 4.5Å; M405-V412 HydrophobicContact CE-CG1 3.66Å; M405-V412 HydrophobicContact CE-CG2 4.1Å; M405-V412 HydrophobicContact SD-CG1 3.8Å; M405-V412 HydrophobicContact SD-CG2 4.5Å; M405-R464 PolarHBondContact O-NH2 3.3Å; M405-R464 VanDerWaalsContact O-NH2 3.12Å
406	G	65.8	Low	82.6	Confident	42 Å²	42	38 Å²	38	43%	0.433	21%	0.207	S	C	.	.			trans	60.5	-3.9	174.6	0	0	0	0	0	116.6	L404	L404-G406 VanDerWaalsContact C-N 3.34Å; L404-G406 PolarHBondContact O-N 2.85Å
407	D	69.1	Low	83.2	Confident	42 Å²	42	36.6 Å²	36.6	23%	0.225	20%	0.199	C	C	.	.	S	Bend	trans	-89.1	159.9	174.8	-81.8	-32.3	0	0	0	110.9	R318 M405 V409 V412 R464	R318-D407 IonicContact NH2-OD1 3.56Å; M405-D407 PolarHBondContact O-N 2.99Å; D407-V409 PolarHBondContact O-N 3.22Å; D407-V412 HydrophobicContact CB-CG2 3.76Å; D407-R464 IonicContact OD1-CZ 2.66Å; D407-R464 IonicContact OD1-NE 3.71Å; D407-R464 IonicContact OD1-NH2 3.07Å; D407-R464 PolarHBondContact OD1-NH2 3.48Å; D407-R464 VanDerWaalsContact OD1-NH2 3.17Å; D407-R464 IonicContact OD2-CZ 3.1Å; D407-R464 IonicContact OD2-NE 3.17Å; D407-R464 IonicContact OD2-NH2 3.72Å; D407-R464 PolarHBondContact OD2-NH2 3.11Å
408	S	78.1	Confident	83.7	Confident	4 Å²	4	33.9 Å²	33.9	3%	0.028	18%	0.177	C	C	.	.			trans	-61.1	136.3	173.6	168.1	0	0	0	0	110.3	R318 D319 L410 L411 V412	R318-S408 VanDerWaalsContact NH2-N 3.16Å; D319-S408 PolarHBondContact OD1-OG 3.28Å; D319-S408 VanDerWaalsContact OD2-CA 3.29Å; D319-S408 WeakPolarHBondContact OD2-CA 3.38Å; S408-L410 PolarHBondContact O-N 2.94Å; S408-L410 VanDerWaalsContact O-N 3.13Å; S408-L411 PolarHBondContact O-N 3.05Å; S408-V412 PolarHBondContact O-N 3.28Å; S408-V412 VanDerWaalsContact O-N 3.16Å
409	V	84.8	Confident	84	Confident	8 Å²	8	33.3 Å²	33.3	5%	0.048	17%	0.174	C	C	.	.	H	α-helix	trans	-55.6	-33.9	-176.3	-66	0	0	0	0	112.3	V68 V144 Y147 T148 D319 D407 A413	V68-V409 HydrophobicContact CB-CG2 4.46Å; V68-V409 VanDerWaalsContact CG1-C 3.49Å; V68-V409 HydrophobicContact CG1-CB 4.07Å; V68-V409 HydrophobicContact CG1-CG2 3.92Å; V68-V409 WeakPolarHBondContact CG1-O 3.45Å; V144-V409 HydrophobicContact CG1-CB 4.12Å; V144-V409 HydrophobicContact CG1-CG1 4.49Å; Y147-V409 HydrophobicContact CD1-CG1 4.4Å; Y147-V409 HydrophobicContact CE1-CG1 4.49Å; T148-V409 HydrophobicContact CG2-CG2 4.28Å; D319-V409 WeakPolarHBondContact OD2-CG2 3.34Å; D319-V409 PolarHBondContact OD2-N 2.93Å; D407-V409 PolarHBondContact O-N 3.22Å; V409-A413 WeakPolarHBondContact O-CB 3.47Å; V409-A413 PolarHBondContact O-N 3.26Å
410	L	87.4	Confident	84.5	Confident	8 Å²	8	33.5 Å²	33.5	4%	0.042	18%	0.175	C	C	.	.	H	α-helix	trans	-65.9	-46.5	177.8	177.2	67.3	0	0	0	112.1	V68 V73 E76 S408 V412 A413 L414	V68-L410 HydrophobicContact CG1-CB 4.31Å; V73-L410 HydrophobicContact CG2-CD1 4.37Å; V73-L410 HydrophobicContact CG2-CD2 3.95Å; E76-L410 HydrophobicContact CB-CD2 4.35Å; S408-L410 PolarHBondContact O-N 2.94Å; S408-L410 VanDerWaalsContact O-N 3.13Å; L410-V412 VanDerWaalsContact C-N 3.31Å; L410-V412 PolarHBondContact O-N 3.34Å; L410-A413 PolarHBondContact O-N 3.43Å; L410-L414 HydrophobicContact CD1-CD1 3.94Å; L410-L414 HydrophobicContact CD1-CG 4.16Å; L410-L414 HydrophobicContact CD2-CD1 4.47Å; L410-L414 HydrophobicContact CG-CD1 3.84Å; L410-L414 HydrophobicContact CG-CG 4.41Å; L410-L414 VanDerWaalsContact O-CG 3.27Å; L410-L414 WeakPolarHBondContact O-CG 3.42Å; L410-L414 PolarHBondContact O-N 3.39Å
411	L	87.2	Confident	85.2	Confident	16 Å²	16	27.7 Å²	27.7	8%	0.084	15%	0.153	C	C	.	.	H	α-helix	trans	-65.2	-39.8	-179.6	-83.8	68.6	0	0	0	110.6	S408 L414 K415 Y505	S408-L411 PolarHBondContact O-N 3.05Å; L411-L414 PolarHBondContact O-N 2.69Å; L411-K415 WeakPolarHBondContact O-CB 3.42Å; L411-K415 VanDerWaalsContact O-CG 3.29Å; L411-K415 WeakPolarHBondContact O-CG 3.25Å; L411-K415 PolarHBondContact O-N 2.98Å; L411-Y505 HydrophobicContact CD2-CE1 4.41Å; L411-Y505 HydrophobicContact CG-CE1 4.19Å
412	V	88	Confident	85.8	Confident	6 Å²	6	23.5 Å²	23.5	4%	0.036	13%	0.131	C	C	.	.	H	α-helix	trans	-59.7	-48.8	175.2	174.9	0	0	0	0	110.4	V144 M405 D407 S408 L410 L414 K415 I416	V144-V412 HydrophobicContact CG2-CG1 3.94Å; M405-V412 HydrophobicContact CB-CG2 4.5Å; M405-V412 HydrophobicContact CE-CG1 3.66Å; M405-V412 HydrophobicContact CE-CG2 4.1Å; M405-V412 HydrophobicContact SD-CG1 3.8Å; M405-V412 HydrophobicContact SD-CG2 4.5Å; D407-V412 HydrophobicContact CB-CG2 3.76Å; S408-V412 PolarHBondContact O-N 3.28Å; S408-V412 VanDerWaalsContact O-N 3.16Å; L410-V412 VanDerWaalsContact C-N 3.31Å; L410-V412 PolarHBondContact O-N 3.34Å; V412-L414 PolarHBondContact O-N 3.4Å; V412-K415 PolarHBondContact O-N 3.46Å; V412-I416 HydrophobicContact CG1-CD1 3.84Å; V412-I416 WeakPolarHBondContact O-CD1 3.26Å; V412-I416 VanDerWaalsContact O-CG1 3.3Å; V412-I416 WeakPolarHBondContact O-CG1 3.44Å; V412-I416 PolarHBondContact O-N 3.36Å
413	A	90.9	Very high	86.7	Confident	6 Å²	6	23 Å²	23	5%	0.05	13%	0.128	C	C	.	.	H	α-helix	trans	-59.9	-47.6	177.8	0	0	0	0	0	112.6	V68 Y141 V409 L410 K415 I416 F417	V68-A413 HydrophobicContact CG1-CB 3.89Å; Y141-A413 HydrophobicContact CD2-CB 4.18Å; Y141-A413 HydrophobicContact CE2-CB 3.89Å; V409-A413 WeakPolarHBondContact O-CB 3.47Å; V409-A413 PolarHBondContact O-N 3.26Å; L410-A413 PolarHBondContact O-N 3.43Å; A413-K415 VanDerWaalsContact C-N 3.33Å; A413-K415 PolarHBondContact O-N 2.88Å; A413-I416 PolarHBondContact O-N 3.5Å; A413-F417 VanDerWaalsContact O-CD2 3.23Å; A413-F417 WeakPolarHBondContact O-CD2 3.33Å; A413-F417 PolarHBondContact O-N 2.84Å; A413-F417 VanDerWaalsContact O-N 3.08Å
414	L	91.7	Very high	87.5	Confident	15 Å²	15	19.2 Å²	19.2	8%	0.079	11%	0.111	C	C	.	.	H	α-helix	trans	-62.5	-39.2	179.5	-66.6	172.3	0	0	0	111.8	Y84 L251 L410 L411 V412 G418 Y505 M506	Y84-L414 HydrophobicContact CE2-CD1 4.25Å; L251-L414 HydrophobicContact CD2-CD2 3.51Å; L410-L414 HydrophobicContact CD1-CD1 3.94Å; L410-L414 HydrophobicContact CD1-CG 4.16Å; L410-L414 HydrophobicContact CD2-CD1 4.47Å; L410-L414 HydrophobicContact CG-CD1 3.84Å; L410-L414 HydrophobicContact CG-CG 4.41Å; L410-L414 VanDerWaalsContact O-CG 3.27Å; L410-L414 WeakPolarHBondContact O-CG 3.42Å; L410-L414 PolarHBondContact O-N 3.39Å; L411-L414 PolarHBondContact O-N 2.69Å; V412-L414 PolarHBondContact O-N 3.4Å; L414-G418 PolarHBondContact O-N 3.43Å; L414-Y505 HydrophobicContact CB-CD2 3.83Å; L414-Y505 HydrophobicContact CB-CE2 3.87Å; L414-Y505 HydrophobicContact CD1-CD2 4.34Å; L414-Y505 HydrophobicContact CD1-CE2 3.51Å; L414-Y505 HydrophobicContact CG-CE2 4.31Å; L414-M506 HydrophobicContact CD1-SD 4.45Å
415	K	91.6	Very high	88.5	Confident	27 Å²	27	14.1 Å²	14.1	12%	0.117	8%	0.084	C	C	.	.	H	α-helix	trans	-63	-43.3	173.4	-74.9	179.5	178.4	-171.1	0	112	L411 V412 A413 G418 M419 Y508	L411-K415 WeakPolarHBondContact O-CB 3.42Å; L411-K415 VanDerWaalsContact O-CG 3.29Å; L411-K415 WeakPolarHBondContact O-CG 3.25Å; L411-K415 PolarHBondContact O-N 2.98Å; V412-K415 PolarHBondContact O-N 3.46Å; A413-K415 VanDerWaalsContact C-N 3.33Å; A413-K415 PolarHBondContact O-N 2.88Å; K415-G418 PolarHBondContact O-N 2.93Å; K415-M419 HydrophobicContact CB-CE 4.2Å; K415-M419 WeakPolarHBondContact O-CB 3.26Å; K415-M419 WeakPolarHBondContact O-CE 3.07Å; K415-M419 VanDerWaalsContact O-CG 3.27Å; K415-M419 WeakPolarHBondContact O-CG 3.19Å; K415-M419 PolarHBondContact O-N 2.97Å; K415-Y508 HydrophobicContact CG-CD2 4.48Å; K415-Y508 HydrophobicContact CG-CE2 4.05Å
416	I	92.5	Very high	89.9	Confident	10 Å²	10	10.6 Å²	10.6	5%	0.051	7%	0.067	C	C	.	.	H	α-helix	trans	-59.7	-50	178.4	-68.5	158.7	0	0	0	110.7	Q137 I140 V144 V412 A413 G418 M419 V420	Q137-I416 HydrophobicContact CG-CG2 4.07Å; I140-I416 HydrophobicContact CG2-CD1 3.59Å; I140-I416 HydrophobicContact CG2-CG1 3.97Å; V144-I416 HydrophobicContact CG2-CD1 3.93Å; V412-I416 HydrophobicContact CG1-CD1 3.84Å; V412-I416 WeakPolarHBondContact O-CD1 3.26Å; V412-I416 VanDerWaalsContact O-CG1 3.3Å; V412-I416 WeakPolarHBondContact O-CG1 3.44Å; V412-I416 PolarHBondContact O-N 3.36Å; A413-I416 PolarHBondContact O-N 3.5Å; I416-G418 VanDerWaalsContact C-N 3.33Å; I416-G418 PolarHBondContact O-N 3.41Å; I416-M419 PolarHBondContact O-N 3.33Å; I416-V420 PolarHBondContact O-N 2.88Å
417	F	92.9	Very high	91.4	Very high	8 Å²	8	8.6 Å²	8.6	4%	0.035	5%	0.046	C	C	.	.	I	π-helix	trans	-64.4	-38.4	177.3	-76.1	-68.1	0	0	0	112.5	F64 Y141 L251 L255 A413 G421 G422	F64-F417 HydrophobicContact CD1-CZ 4.44Å; F64-F417 AromaticContact CE1-CE1 3.94Å; F64-F417 HydrophobicContact CE1-CE1 3.94Å; F64-F417 HydrophobicContact CE1-CE2 4.31Å; F64-F417 AromaticContact CE1-CZ 3.57Å; F64-F417 HydrophobicContact CE1-CZ 3.57Å; F64-F417 HydrophobicContact CZ-CE1 4.43Å; F64-F417 HydrophobicContact CZ-CZ 4.41Å; Y141-F417 AromaticContact CD1-CE2 3.98Å; Y141-F417 HydrophobicContact CD1-CE2 3.98Å; Y141-F417 AromaticContact CD1-CZ 3.5Å; Y141-F417 HydrophobicContact CD1-CZ 3.5Å; Y141-F417 AromaticContact CD2-CE2 3.6Å; Y141-F417 HydrophobicContact CD2-CE2 3.6Å; Y141-F417 AromaticContact CD2-CZ 3.98Å; Y141-F417 HydrophobicContact CD2-CZ 3.98Å; Y141-F417 AromaticContact CE1-CE2 3.93Å; Y141-F417 HydrophobicContact CE1-CE2 3.93Å; Y141-F417 AromaticContact CE1-CZ 3.62Å; Y141-F417 HydrophobicContact CE1-CZ 3.62Å; Y141-F417 AromaticContact CE2-CE2 3.54Å; Y141-F417 HydrophobicContact CE2-CE2 3.54Å; Y141-F417 HydrophobicContact CE2-CZ 4.08Å; Y141-F417 AromaticContact CG-CE2 3.83Å; Y141-F417 HydrophobicContact CG-CE2 3.83Å; Y141-F417 AromaticContact CG-CZ 3.71Å; Y141-F417 HydrophobicContact CG-CZ 3.71Å; Y141-F417 AromaticContact CZ-CE2 3.71Å; Y141-F417 AromaticContact CZ-CZ 3.91Å; L251-F417 HydrophobicContact CD1-CB 3.54Å; L255-F417 HydrophobicContact CD2-CD1 3.27Å; L255-F417 HydrophobicContact CD2-CD2 4.06Å; L255-F417 HydrophobicContact CD2-CE1 3.35Å; L255-F417 HydrophobicContact CD2-CE2 4.11Å; L255-F417 HydrophobicContact CD2-CG 3.7Å; L255-F417 HydrophobicContact CD2-CZ 3.81Å; L255-F417 HydrophobicContact CG-CD1 4.42Å; A413-F417 VanDerWaalsContact O-CD2 3.23Å; A413-F417 WeakPolarHBondContact O-CD2 3.33Å; A413-F417 PolarHBondContact O-N 2.84Å; A413-F417 VanDerWaalsContact O-N 3.08Å; F417-G421 CarbonylContact O-C 3.28Å; F417-G421 WeakPolarHBondContact O-CA 3.16Å; F417-G421 PolarHBondContact O-N 3.42Å; F417-G422 PolarHBondContact O-N 2.67Å
418	G	92.8	Very high	92.8	Very high	1 Å²	1	6.6 Å²	6.6	1%	0.01	4%	0.035	C	C	.	.	I	π-helix	trans	-63.1	-48.4	175.5	0	0	0	0	0	113.1	L414 K415 I416 G422 Y508 A509 S512	L414-G418 PolarHBondContact O-N 3.43Å; K415-G418 PolarHBondContact O-N 2.93Å; I416-G418 VanDerWaalsContact C-N 3.33Å; I416-G418 PolarHBondContact O-N 3.41Å; G418-G422 PolarHBondContact O-N 3.2Å; G418-Y508 CarbonylContact O-C 3.59Å; G418-A509 WeakPolarHBondContact O-CA 3.07Å; G418-A509 PolarHBondContact O-N 3.48Å; G418-S512 PolarHBondContact O-OG 3.04Å
419	M	94.3	Very high	93.7	Very high	21 Å²	21	7 Å²	7	10%	0.103	4%	0.038	C	C	.	.	I	π-helix	trans	-73.6	-39.2	-174.1	-70.4	-176.8	-62.9	0	0	113.4	K415 I416 P423 A453 G457 Y508	K415-M419 HydrophobicContact CB-CE 4.2Å; K415-M419 WeakPolarHBondContact O-CB 3.26Å; K415-M419 WeakPolarHBondContact O-CE 3.07Å; K415-M419 VanDerWaalsContact O-CG 3.27Å; K415-M419 WeakPolarHBondContact O-CG 3.19Å; K415-M419 PolarHBondContact O-N 2.97Å; I416-M419 PolarHBondContact O-N 3.33Å; M419-P423 WeakPolarHBondContact O-CD 3.37Å; M419-P423 VanDerWaalsContact O-CG 3.28Å; M419-P423 WeakPolarHBondContact O-CG 3.17Å; M419-A453 HydrophobicContact CB-CB 4.18Å; M419-A453 WeakPolarHBondContact O-CB 3.48Å; M419-G457 VanDerWaalsContact SD-CA 3.59Å; M419-Y508 HydrophobicContact CG-CD2 3.8Å; M419-Y508 HydrophobicContact CG-CE2 4.34Å
420	V	96.3	Very high	94.2	Very high	3 Å²	3	6.6 Å²	6.6	2%	0.018	4%	0.035	C	C	.	.	I	π-helix	trans	-107.7	-34.3	-173.3	-166.2	0	0	0	0	112.1	T133 F136 Q137 I416 P423 I424 L450 F454	T133-V420 HydrophobicContact CG2-CG1 3.51Å; T133-V420 WeakPolarHBondContact O-CG1 3.28Å; F136-V420 HydrophobicContact CD1-CG1 4.26Å; F136-V420 HydrophobicContact CD1-CG2 4.23Å; F136-V420 HydrophobicContact CE1-CG2 4.11Å; Q137-V420 HydrophobicContact CB-CB 3.89Å; Q137-V420 HydrophobicContact CB-CG1 3.6Å; Q137-V420 HydrophobicContact CG-CB 3.91Å; Q137-V420 HydrophobicContact CG-CG1 4.16Å; Q137-V420 VanDerWaalsContact OE1-C 3.28Å; I416-V420 PolarHBondContact O-N 2.88Å; V420-P423 WeakPolarHBondContact O-CD 3.38Å; V420-I424 WeakPolarHBondContact O-CG1 3.34Å; V420-L450 HydrophobicContact CG1-CD2 4.31Å; V420-F454 HydrophobicContact CG2-CE1 4.47Å; V420-F454 HydrophobicContact CG2-CZ 4.02Å
421	G	95.6	Very high	94.5	Very high	2 Å²	2	6.2 Å²	6.2	2%	0.021	3%	0.033	C	C	.	.	I	π-helix	trans	-72.8	-31.8	176.6	0	0	0	0	0	113	F417 I424 L425	F417-G421 CarbonylContact O-C 3.28Å; F417-G421 WeakPolarHBondContact O-CA 3.16Å; F417-G421 PolarHBondContact O-N 3.42Å; G421-I424 PolarHBondContact O-N 2.88Å; G421-L425 WeakPolarHBondContact O-CB 3.5Å; G421-L425 PolarHBondContact O-N 3.17Å
422	G	96.6	Very high	94.8	Very high	0 Å²	0	5.4 Å²	5.4	0%	0	3%	0.029	C	C	.	.	H	α-helix	trans	-60.2	-50.7	175.3	0	0	0	0	0	114.2	F417 G418 I424 L425 G426 S512 C513	F417-G422 PolarHBondContact O-N 2.67Å; G418-G422 PolarHBondContact O-N 3.2Å; G422-I424 PolarHBondContact O-N 3.45Å; G422-L425 WeakPolarHBondContact O-CB 3.29Å; G422-L425 PolarHBondContact O-N 2.92Å; G422-G426 PolarHBondContact O-N 3.34Å; G422-S512 WeakPolarHBondContact CA-OG 3.38Å; G422-C513 WeakPolarHBondContact O-CA 3.27Å
423	P	98.1	Very high	95	Very high	0 Å²	0	7.2 Å²	7.2	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-59.9	-40.6	173.9	-26.1	33.9	0	0	0	113.8	M419 V420 G426 L427 L446 L450 A453 S512 V516	M419-P423 WeakPolarHBondContact O-CD 3.37Å; M419-P423 VanDerWaalsContact O-CG 3.28Å; M419-P423 WeakPolarHBondContact O-CG 3.17Å; V420-P423 WeakPolarHBondContact O-CD 3.38Å; P423-G426 PolarHBondContact O-N 3.34Å; P423-L427 PolarHBondContact O-N 3.48Å; P423-L446 HydrophobicContact CB-CD1 3.86Å; P423-L450 HydrophobicContact CB-CD2 4.07Å; P423-L450 HydrophobicContact CB-CG 4.06Å; P423-L450 HydrophobicContact CG-CD2 3.88Å; P423-L450 HydrophobicContact CG-CG 4.17Å; P423-A453 HydrophobicContact CG-CB 4.38Å; P423-S512 VanDerWaalsContact CD-OG 3.28Å; P423-S512 WeakPolarHBondContact CD-OG 3.24Å; P423-V516 HydrophobicContact CB-CG2 3.99Å
424	I	97.7	Very high	95	Very high	4 Å²	4	9.3 Å²	9.3	2%	0.021	5%	0.045	C	C	.	.	H	α-helix	trans	-61.8	-47.6	175.3	-65.1	173	0	0	0	109.9	Y115 T133 F134 V258 V420 G421 G422 G426 L427 F428	Y115-I424 HydrophobicContact CE1-CG2 4.13Å; T133-I424 HydrophobicContact CG2-CD1 3.9Å; T133-I424 HydrophobicContact CG2-CG1 3.75Å; F134-I424 HydrophobicContact CB-CD1 3.99Å; V258-I424 HydrophobicContact CB-CG2 4.48Å; V258-I424 HydrophobicContact CG2-CG2 4.09Å; V420-I424 WeakPolarHBondContact O-CG1 3.34Å; G421-I424 PolarHBondContact O-N 2.88Å; G422-I424 PolarHBondContact O-N 3.45Å; I424-G426 VanDerWaalsContact C-N 3.31Å; I424-G426 PolarHBondContact O-N 3.04Å; I424-L427 WeakPolarHBondContact O-CB 3.22Å; I424-L427 PolarHBondContact O-N 2.99Å; I424-L427 VanDerWaalsContact O-N 3.13Å; I424-F428 HydrophobicContact CG2-CD2 3.97Å; I424-F428 HydrophobicContact CG2-CE2 3.93Å; I424-F428 WeakPolarHBondContact O-CD2 3.34Å; I424-F428 PolarHBondContact O-N 2.68Å; I424-F428 VanDerWaalsContact O-N 3.11Å
425	L	97.9	Very high	94.8	Very high	0 Å²	0	10.2 Å²	10.2	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-56.6	-46.4	175.4	175.4	64	0	0	0	111.3	F102 F250 L253 V258 G421 G422 L427 F428 C429	F102-L425 HydrophobicContact CE1-CD1 4.27Å; F102-L425 HydrophobicContact CZ-CD1 4.13Å; F250-L425 HydrophobicContact CB-CD2 4.37Å; F250-L425 HydrophobicContact CD1-CD2 4.12Å; F250-L425 VanDerWaalsContact O-CD2 3.32Å; F250-L425 WeakPolarHBondContact O-CD2 3.3Å; L253-L425 HydrophobicContact CB-CD1 3.81Å; L253-L425 HydrophobicContact CB-CD2 3.63Å; L253-L425 HydrophobicContact CB-CG 4.39Å; L253-L425 HydrophobicContact CD1-CD2 4.48Å; V258-L425 HydrophobicContact CG1-CD1 4.11Å; V258-L425 HydrophobicContact CG2-CB 4.22Å; V258-L425 HydrophobicContact CG2-CD1 4.29Å; G421-L425 WeakPolarHBondContact O-CB 3.5Å; G421-L425 PolarHBondContact O-N 3.17Å; G422-L425 WeakPolarHBondContact O-CB 3.29Å; G422-L425 PolarHBondContact O-N 2.92Å; L425-L427 VanDerWaalsContact C-N 3.26Å; L425-L427 PolarHBondContact O-N 3.5Å; L425-F428 PolarHBondContact O-N 3.09Å; L425-C429 WeakPolarHBondContact O-CB 3.06Å; L425-C429 PolarHBondContact O-N 3.03Å; L425-C429 PolarHBondContact O-SG 2.93Å
426	G	97.9	Very high	94.6	Very high	0 Å²	0	13.3 Å²	13.3	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-57.2	-39.2	176.6	0	0	0	0	0	112.9	G422 P423 I424 C429 L430 C513	G422-G426 PolarHBondContact O-N 3.34Å; P423-G426 PolarHBondContact O-N 3.34Å; I424-G426 VanDerWaalsContact C-N 3.31Å; I424-G426 PolarHBondContact O-N 3.04Å; G426-C429 PolarHBondContact O-N 3.45Å; G426-L430 VanDerWaalsContact O-CB 3.24Å; G426-L430 WeakPolarHBondContact O-CB 3.48Å; G426-L430 PolarHBondContact O-N 2.92Å; G426-C513 WeakPolarHBondContact CA-SG 3.16Å
427	L	98.1	Very high	94.6	Very high	0 Å²	0	12.8 Å²	12.8	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-66.7	-43.4	178.7	-175.4	61.5	0	0	0	112.5	L118 V126 P423 I424 L425 L430 G431 A442 L446 V516	L118-L427 HydrophobicContact CD1-CD2 3.58Å; L118-L427 HydrophobicContact CD1-CG 4.15Å; L118-L427 HydrophobicContact CD2-CD2 4.37Å; L118-L427 HydrophobicContact CD2-CG 4.01Å; V126-L427 HydrophobicContact CG1-CD1 3.88Å; V126-L427 HydrophobicContact CG1-CD2 4Å; V126-L427 HydrophobicContact CG1-CG 4.29Å; P423-L427 PolarHBondContact O-N 3.48Å; I424-L427 WeakPolarHBondContact O-CB 3.22Å; I424-L427 PolarHBondContact O-N 2.99Å; I424-L427 VanDerWaalsContact O-N 3.13Å; L425-L427 VanDerWaalsContact C-N 3.26Å; L425-L427 PolarHBondContact O-N 3.5Å; L427-L430 PolarHBondContact O-N 3.32Å; L427-G431 PolarHBondContact O-N 3.45Å; L427-G431 VanDerWaalsContact O-N 3.09Å; L427-A442 HydrophobicContact CD1-CB 3.8Å; L427-L446 HydrophobicContact CD2-CD1 4.33Å; L427-L446 HydrophobicContact CD2-CD2 4.04Å; L427-V516 HydrophobicContact CB-CG1 4.41Å
428	F	97.5	Very high	94.7	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-67.5	-43.4	174.2	-84.2	-93.7	0	0	0	111.6	F102 L106 A114 Y115 Y117 L118 V258 I424 L425 L430 G431 M432	F102-F428 HydrophobicContact CE1-CB 4.47Å; L106-F428 HydrophobicContact CD2-CE1 4.45Å; A114-F428 HydrophobicContact CB-CE1 4.46Å; A114-F428 HydrophobicContact CB-CZ 4.05Å; A114-F428 WeakPolarHBondContact O-CE1 3.37Å; A114-F428 WeakPolarHBondContact O-CZ 3.05Å; Y115-F428 HydrophobicContact CD1-CE2 4.05Å; Y115-F428 HydrophobicContact CD1-CZ 4.16Å; Y115-F428 AromaticContact CE1-CE2 3.83Å; Y115-F428 HydrophobicContact CE1-CE2 3.83Å; Y115-F428 HydrophobicContact CE1-CZ 4.24Å; Y117-F428 AromaticContact CD1-CD1 3.5Å; Y117-F428 HydrophobicContact CD1-CD1 3.5Å; Y117-F428 VanDerWaalsContact CD1-CD1 3.5Å; Y117-F428 AromaticContact CD1-CE1 3.5Å; Y117-F428 HydrophobicContact CD1-CE1 3.5Å; Y117-F428 AromaticContact CE1-CD1 3.8Å; Y117-F428 HydrophobicContact CE1-CD1 3.8Å; Y117-F428 HydrophobicContact CE1-CE1 4.28Å; Y117-F428 HydrophobicContact CG-CE1 4.25Å; L118-F428 HydrophobicContact CD1-CE2 4.13Å; L118-F428 HydrophobicContact CD1-CZ 4.37Å; L118-F428 HydrophobicContact CD2-CD1 4.38Å; L118-F428 HydrophobicContact CD2-CD2 4.38Å; L118-F428 HydrophobicContact CD2-CE1 4.45Å; L118-F428 HydrophobicContact CD2-CE2 4.42Å; L118-F428 HydrophobicContact CD2-CG 4.37Å; L118-F428 HydrophobicContact CD2-CZ 4.46Å; L118-F428 HydrophobicContact CG-CE2 4.36Å; L118-F428 HydrophobicContact CG-CZ 4.22Å; V258-F428 HydrophobicContact CB-CD2 3.86Å; V258-F428 HydrophobicContact CB-CE2 4.17Å; V258-F428 HydrophobicContact CB-CG 4.12Å; V258-F428 HydrophobicContact CG1-CB 3.56Å; V258-F428 HydrophobicContact CG1-CD1 4.08Å; V258-F428 HydrophobicContact CG1-CD2 3.79Å; V258-F428 HydrophobicContact CG1-CE2 4.48Å; V258-F428 HydrophobicContact CG1-CG 3.54Å; I424-F428 HydrophobicContact CG2-CD2 3.97Å; I424-F428 HydrophobicContact CG2-CE2 3.93Å; I424-F428 WeakPolarHBondContact O-CD2 3.34Å; I424-F428 PolarHBondContact O-N 2.68Å; I424-F428 VanDerWaalsContact O-N 3.11Å; L425-F428 PolarHBondContact O-N 3.09Å; F428-L430 VanDerWaalsContact C-N 3.31Å; F428-L430 PolarHBondContact O-N 3.42Å; F428-G431 PolarHBondContact O-N 3.47Å; F428-M432 HydrophobicContact CB-CE 4.49Å; F428-M432 HydrophobicContact CD1-CE 3.79Å; F428-M432 WeakPolarHBondContact O-CB 3.41Å; F428-M432 VanDerWaalsContact O-CG 3.32Å; F428-M432 WeakPolarHBondContact O-CG 3.45Å; F428-M432 PolarHBondContact O-N 3Å
429	C	97.1	Very high	94.9	Very high	11 Å²	11	14.5 Å²	14.5	7%	0.074	7%	0.071	C	C	.	.	H	α-helix	trans	-59.5	-42.4	175	-72.7	0	0	0	0	111.6	L425 G426 G431 M432 F433 I517	L425-C429 WeakPolarHBondContact O-CB 3.06Å; L425-C429 PolarHBondContact O-N 3.03Å; L425-C429 PolarHBondContact O-SG 2.93Å; G426-C429 PolarHBondContact O-N 3.45Å; C429-G431 VanDerWaalsContact C-N 3.33Å; C429-G431 PolarHBondContact O-N 2.85Å; C429-M432 PolarHBondContact O-N 2.94Å; C429-F433 HydrophobicContact CB-CD2 3.92Å; C429-F433 HydrophobicContact CB-CE2 4.07Å; C429-F433 WeakPolarHBondContact O-CB 3.47Å; C429-F433 VanDerWaalsContact O-CD2 3.32Å; C429-F433 WeakPolarHBondContact O-CD2 3.44Å; C429-F433 PolarHBondContact O-N 2.75Å; C429-I517 HydrophobicContact CB-CD1 4.02Å
430	L	96.6	Very high	95	Very high	0 Å²	0	20.1 Å²	20.1	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-58.3	-45.8	175.2	-176.1	64.9	0	0	0	110.9	F122 G426 L427 F428 F434 A437 A442 L521	F122-L430 HydrophobicContact CZ-CG 4.39Å; G426-L430 VanDerWaalsContact O-CB 3.24Å; G426-L430 WeakPolarHBondContact O-CB 3.48Å; G426-L430 PolarHBondContact O-N 2.92Å; L427-L430 PolarHBondContact O-N 3.32Å; F428-L430 VanDerWaalsContact C-N 3.31Å; F428-L430 PolarHBondContact O-N 3.42Å; L430-F434 HydrophobicContact CD1-CB 4.34Å; L430-F434 HydrophobicContact CD1-CD2 4.23Å; L430-F434 HydrophobicContact CD1-CG 4.43Å; L430-F434 WeakPolarHBondContact O-CB 3.1Å; L430-F434 PolarHBondContact O-N 3.03Å; L430-A437 HydrophobicContact CD1-CB 3.66Å; L430-A437 HydrophobicContact CD2-CB 4.39Å; L430-A437 HydrophobicContact CG-CB 3.74Å; L430-A442 HydrophobicContact CD2-CB 4.37Å; L430-L521 HydrophobicContact CD1-CD2 3.83Å; L430-L521 HydrophobicContact CD1-CG 3.86Å
431	G	94.2	Very high	95	Very high	0 Å²	0	20 Å²	20	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-67.3	-45	177.2	0	0	0	0	0	114.2	Y117 R121 F122 L427 F428 C429	Y117-G431 PolarHBondContact OH-O 3.47Å; R121-G431 PolarHBondContact NE-O 3.36Å; F122-G431 VanDerWaalsContact CZ-CA 3.44Å; L427-G431 PolarHBondContact O-N 3.45Å; L427-G431 VanDerWaalsContact O-N 3.09Å; F428-G431 PolarHBondContact O-N 3.47Å; C429-G431 VanDerWaalsContact C-N 3.33Å; C429-G431 PolarHBondContact O-N 2.85Å
432	M	93.3	Very high	95.2	Very high	0 Å²	0	19.9 Å²	19.9	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-76.6	-36.2	-172	-71.3	-169.5	-168.3	0	0	112.6	F102 L105 L106 Y117 F428 C429 Y541	F102-M432 HydrophobicContact CD1-CE 3.61Å; F102-M432 HydrophobicContact CD1-SD 3.76Å; F102-M432 HydrophobicContact CE1-CE 4.07Å; F102-M432 HydrophobicContact CE1-SD 3.88Å; F102-M432 HydrophobicContact CG-CE 4.4Å; F102-M432 HydrophobicContact CG-SD 4.29Å; L105-M432 HydrophobicContact CD1-CG 4.2Å; L105-M432 HydrophobicContact CD1-SD 4.3Å; L105-M432 HydrophobicContact CD2-CE 3.99Å; L105-M432 HydrophobicContact CD2-SD 4.47Å; L106-M432 HydrophobicContact CD1-CE 4.46Å; L106-M432 HydrophobicContact CD2-CE 4.3Å; L106-M432 HydrophobicContact CG-CE 4.3Å; Y117-M432 HydrophobicContact CE1-CE 4.26Å; Y117-M432 HydrophobicContact CE1-CG 4.04Å; Y117-M432 HydrophobicContact CE2-CG 4.48Å; Y117-M432 VanDerWaalsContact OH-CA 3.27Å; Y117-M432 WeakPolarHBondContact OH-CA 3.39Å; Y117-M432 WeakPolarHBondContact OH-CG 3.36Å; Y117-M432 PolarHBondContact OH-N 2.99Å; F428-M432 HydrophobicContact CB-CE 4.49Å; F428-M432 HydrophobicContact CD1-CE 3.79Å; F428-M432 WeakPolarHBondContact O-CB 3.41Å; F428-M432 VanDerWaalsContact O-CG 3.32Å; F428-M432 WeakPolarHBondContact O-CG 3.45Å; F428-M432 PolarHBondContact O-N 3Å; C429-M432 PolarHBondContact O-N 2.94Å; M432-Y541 PolarHBondContact O-N 3.26Å
433	F	91.9	Very high	95.2	Very high	44 Å²	44	22.4 Å²	22.4	19%	0.193	11%	0.109	C	C	.	.	H	α-helix	trans	-106.1	-17.5	-169.9	-55.7	-49.8	0	0	0	114.5	V101 F102 C429 Y541 L543	V101-F433 HydrophobicContact CG1-CE1 3.59Å; V101-F433 HydrophobicContact CG1-CZ 3.71Å; F102-F433 HydrophobicContact CE2-CZ 4.42Å; F102-F433 HydrophobicContact CZ-CZ 4.46Å; C429-F433 HydrophobicContact CB-CD2 3.92Å; C429-F433 HydrophobicContact CB-CE2 4.07Å; C429-F433 WeakPolarHBondContact O-CB 3.47Å; C429-F433 VanDerWaalsContact O-CD2 3.32Å; C429-F433 WeakPolarHBondContact O-CD2 3.44Å; C429-F433 PolarHBondContact O-N 2.75Å; F433-Y541 HydrophobicContact CE1-CD1 4.36Å; F433-L543 HydrophobicContact CD1-CB 3.96Å; F433-L543 HydrophobicContact CD1-CD1 4.23Å; F433-L543 HydrophobicContact CD1-CD2 4.27Å; F433-L543 HydrophobicContact CD1-CG 4.38Å; F433-L543 HydrophobicContact CE1-CB 4.4Å; F433-L543 HydrophobicContact CE1-CD1 3.86Å; F433-L543 HydrophobicContact CE1-CG 4.49Å
434	F	91.3	Very high	95.2	Very high	50 Å²	50	24.2 Å²	24.2	22%	0.219	12%	0.123	C	C	.	.			trans	-119.5	98.5	-174.7	-57	-89.3	0	0	0	110.7	R121 L430 W436 A437 I517 L521	R121-F434 PolarHBondContact NH2-O 3.44Å; L430-F434 HydrophobicContact CD1-CB 4.34Å; L430-F434 HydrophobicContact CD1-CD2 4.23Å; L430-F434 HydrophobicContact CD1-CG 4.43Å; L430-F434 WeakPolarHBondContact O-CB 3.1Å; L430-F434 PolarHBondContact O-N 3.03Å; F434-W436 VanDerWaalsContact C-N 3.27Å; F434-W436 AromaticContact CD1-CE2 3.97Å; F434-W436 AromaticContact CD1-CZ2 3.81Å; F434-W436 HydrophobicContact CD1-CZ2 3.81Å; F434-W436 AromaticContact CD1-NE1 3.72Å; F434-W436 PolarHBondContact O-N 3.22Å; F434-A437 HydrophobicContact CB-CB 4.22Å; F434-A437 WeakPolarHBondContact O-CB 3.21Å; F434-A437 PolarHBondContact O-N 3.43Å; F434-I517 HydrophobicContact CE2-CD1 4.43Å; F434-I517 HydrophobicContact CE2-CG2 3.79Å; F434-I517 HydrophobicContact CZ-CG2 3.78Å; F434-L521 HydrophobicContact CB-CD2 3.87Å; F434-L521 HydrophobicContact CD1-CD1 3.82Å; F434-L521 HydrophobicContact CD1-CD2 3.86Å; F434-L521 HydrophobicContact CD1-CG 4.39Å; F434-L521 HydrophobicContact CE1-CD1 3.76Å; F434-L521 HydrophobicContact CG-CD1 4.39Å; F434-L521 HydrophobicContact CG-CD2 3.92Å; F434-L521 HydrophobicContact CZ-CD1 4.28Å
435	P	86.8	Confident	95.3	Very high	34 Å²	34	24 Å²	24	22%	0.221	12%	0.122	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.8	-30	-176.9	24.2	-31.7	0	0	0	112.8	R121 A437 V540	R121-P435 PolarHBondContact NH2-O 3.02Å; P435-A437 VanDerWaalsContact C-N 3.29Å; P435-A437 PolarHBondContact O-N 3.47Å; P435-V540 HydrophobicContact CB-CG1 4.34Å
436	W	87.3	Confident	95.3	Very high	91 Å²	91	24.2 Å²	24.2	35%	0.345	12%	0.124	S	C	.	.	T	Hydrogen-bonded Turn	trans	-76.4	-9.9	179.5	44.3	77.2	0	0	0	114.6	F434 L521 F525 P529 M530	F434-W436 VanDerWaalsContact C-N 3.27Å; F434-W436 AromaticContact CD1-CE2 3.97Å; F434-W436 AromaticContact CD1-CZ2 3.81Å; F434-W436 HydrophobicContact CD1-CZ2 3.81Å; F434-W436 AromaticContact CD1-NE1 3.72Å; F434-W436 PolarHBondContact O-N 3.22Å; W436-L521 VanDerWaalsContact CD1-CD2 3.43Å; W436-F525 HydrophobicContact CB-CE1 4.33Å; W436-F525 AromaticContact CD1-CZ 3.49Å; W436-F525 VanDerWaalsContact CD1-CZ 3.49Å; W436-F525 HydrophobicContact CG-CE1 4.2Å; W436-F525 AromaticContact CG-CZ 3.98Å; W436-F525 HydrophobicContact CG-CZ 3.98Å; W436-F525 AromaticContact NE1-CZ 3.78Å; W436-P529 HydrophobicContact CB-CB 4.15Å; W436-M530 PolarHBondContact O-N 3.44Å
437	A	93.5	Very high	95.3	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	14%	0.14	C	C	.	.			trans	-67.2	136.2	177.3	0	0	0	0	0	111	R121 F122 L430 F434 P435 S524 M530	R121-A437 PolarHBondContact NH1-O 2.79Å; R121-A437 PolarHBondContact NH2-O 3.5Å; F122-A437 HydrophobicContact CE1-CB 3.98Å; F122-A437 WeakPolarHBondContact CE1-O 3.35Å; F122-A437 HydrophobicContact CZ-CB 4.27Å; L430-A437 HydrophobicContact CD1-CB 3.66Å; L430-A437 HydrophobicContact CD2-CB 4.39Å; L430-A437 HydrophobicContact CG-CB 3.74Å; F434-A437 HydrophobicContact CB-CB 4.22Å; F434-A437 WeakPolarHBondContact O-CB 3.21Å; F434-A437 PolarHBondContact O-N 3.43Å; P435-A437 VanDerWaalsContact C-N 3.29Å; P435-A437 PolarHBondContact O-N 3.47Å; A437-S524 WeakPolarHBondContact CA-OG 3.49Å; A437-M530 WeakPolarHBondContact O-CB 3.28Å
438	N	94.7	Very high	95.3	Very high	14 Å²	14	27.3 Å²	27.3	8%	0.075	15%	0.152	C	C	.	.			trans	-114.1	172.9	179.7	75.5	29.3	0	0	0	112.3	K440 G441 A442 S524 T527 G528 M530	N438-K440 PolarHBondContact O-N 3.17Å; N438-K440 PolarHBondContact OD1-N 3.03Å; N438-G441 PolarHBondContact O-N 2.77Å; N438-G441 PolarHBondContact OD1-N 3.42Å; N438-A442 WeakPolarHBondContact O-CB 3.18Å; N438-A442 PolarHBondContact O-N 2.93Å; N438-S524 PolarHBondContact N-OG 3.24Å; N438-S524 WeakPolarHBondContact ND2-CA 3.38Å; N438-S524 PolarHBondContact ND2-O 3.19Å; N438-T527 PolarHBondContact ND2-OG1 3.43Å; N438-G528 PolarHBondContact ND2-O 3.4Å; N438-M530 HydrophobicContact CB-CB 4.15Å
439	S	96.1	Very high	95.3	Very high	30 Å²	30	27.3 Å²	27.3	21%	0.21	15%	0.152	C	C	.	.	H	α-helix	trans	-63.5	-36.6	-176.7	-55.3	0	0	0	0	114.1	F122 A442 V443	F122-S439 WeakPolarHBondContact CA-OG 3.3Å; F122-S439 WeakPolarHBondContact CB-OG 3.46Å; F122-S439 PolarHBondContact O-OG 2.99Å; S439-A442 PolarHBondContact O-N 3.32Å; S439-V443 WeakPolarHBondContact O-CG2 3.17Å; S439-V443 PolarHBondContact O-N 2.87Å; S439-V443 VanDerWaalsContact O-N 3.12Å
440	K	96.5	Very high	95.3	Very high	140 Å²	140	28.3 Å²	28.3	61%	0.609	16%	0.157	S	C	*	.	H	α-helix	trans	-67.2	-44.1	178.7	-67.1	179.2	-179.7	176.5	0	110.5	N438 V443 A444 T527	N438-K440 PolarHBondContact O-N 3.17Å; N438-K440 PolarHBondContact OD1-N 3.03Å; K440-V443 PolarHBondContact O-N 2.92Å; K440-A444 WeakPolarHBondContact O-CB 3.24Å; K440-A444 PolarHBondContact O-N 3.41Å; K440-T527 HydrophobicContact CB-CG2 4.43Å; K440-T527 HydrophobicContact CD-CG2 4.04Å
441	G	97.3	Very high	95.4	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-62.1	-42.6	173.4	0	0	0	0	0	112.4	N438 V443 A444 G445 G520	N438-G441 PolarHBondContact O-N 2.77Å; N438-G441 PolarHBondContact OD1-N 3.42Å; G441-V443 PolarHBondContact O-N 2.7Å; G441-A444 PolarHBondContact O-N 2.93Å; G441-G445 WeakPolarHBondContact O-CA 3.22Å; G441-G445 PolarHBondContact O-N 3.18Å; G441-G520 WeakPolarHBondContact CA-O 3.35Å; G441-G520 WeakPolarHBondContact O-CA 3.34Å
442	A	97.8	Very high	95.4	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-58.5	-46.1	176.9	0	0	0	0	0	113	F122 V126 L427 L430 N438 S439 L446	F122-A442 HydrophobicContact CD1-CB 4.04Å; F122-A442 HydrophobicContact CD2-CB 4.03Å; F122-A442 HydrophobicContact CE1-CB 4.05Å; F122-A442 HydrophobicContact CE2-CB 4.03Å; F122-A442 HydrophobicContact CG-CB 4.02Å; F122-A442 HydrophobicContact CZ-CB 4.02Å; V126-A442 HydrophobicContact CG1-CB 4.05Å; V126-A442 HydrophobicContact CG2-CB 3.89Å; L427-A442 HydrophobicContact CD1-CB 3.8Å; L430-A442 HydrophobicContact CD2-CB 4.37Å; N438-A442 WeakPolarHBondContact O-CB 3.18Å; N438-A442 PolarHBondContact O-N 2.93Å; S439-A442 PolarHBondContact O-N 3.32Å; A442-L446 WeakPolarHBondContact O-CB 2.93Å; A442-L446 PolarHBondContact O-N 2.87Å
443	V	98.1	Very high	95.5	Very high	53 Å²	53	34 Å²	34	32%	0.321	19%	0.194	S	C	.	.	H	α-helix	trans	-66.9	-47.6	177.1	177.3	0	0	0	0	111.6	V125 V126 S439 K440 G441 G445 L446 G447	V125-V443 HydrophobicContact CG1-CG2 4.03Å; V126-V443 HydrophobicContact CG2-CG2 3.75Å; S439-V443 WeakPolarHBondContact O-CG2 3.17Å; S439-V443 PolarHBondContact O-N 2.87Å; S439-V443 VanDerWaalsContact O-N 3.12Å; K440-V443 PolarHBondContact O-N 2.92Å; G441-V443 PolarHBondContact O-N 2.7Å; V443-G445 VanDerWaalsContact C-N 3.33Å; V443-G445 PolarHBondContact O-N 2.96Å; V443-L446 PolarHBondContact O-N 3.03Å; V443-G447 PolarHBondContact O-N 3.16Å
444	A	98.2	Very high	95.6	Very high	37 Å²	37	34.9 Å²	34.9	31%	0.306	20%	0.198	S	C	.	.	H	α-helix	trans	-63	-41.2	-180	0	0	0	0	0	111.9	K440 G441 G447 A448 V523	K440-A444 WeakPolarHBondContact O-CB 3.24Å; K440-A444 PolarHBondContact O-N 3.41Å; G441-A444 PolarHBondContact O-N 2.93Å; A444-G447 PolarHBondContact O-N 3.31Å; A444-A448 WeakPolarHBondContact O-CB 3.39Å; A444-A448 PolarHBondContact O-N 3.28Å; A444-V523 HydrophobicContact CB-CB 4.24Å; A444-V523 HydrophobicContact CB-CG1 4.02Å; A444-V523 HydrophobicContact CB-CG2 3.94Å
445	G	98.3	Very high	95.7	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-59.2	-53.1	174.3	0	0	0	0	0	111.3	G441 V443 G447 A448 G449 V516	G441-G445 WeakPolarHBondContact O-CA 3.22Å; G441-G445 PolarHBondContact O-N 3.18Å; V443-G445 VanDerWaalsContact C-N 3.33Å; V443-G445 PolarHBondContact O-N 2.96Å; G445-G447 VanDerWaalsContact C-N 3.34Å; G445-G447 PolarHBondContact O-N 2.89Å; G445-A448 PolarHBondContact O-N 3.41Å; G445-G449 PolarHBondContact O-N 3.36Å; G445-V516 WeakPolarHBondContact O-CG2 3Å
446	L	98.4	Very high	95.9	Very high	5 Å²	5	37.9 Å²	37.9	3%	0.026	20%	0.204	C	C	.	.	H	α-helix	trans	-56.4	-47.1	177.4	178.4	66.3	0	0	0	111.7	C129 P423 L427 A442 V443 G449 L450	C129-L446 HydrophobicContact CB-CD2 3.66Å; P423-L446 HydrophobicContact CB-CD1 3.86Å; L427-L446 HydrophobicContact CD2-CD1 4.33Å; L427-L446 HydrophobicContact CD2-CD2 4.04Å; A442-L446 WeakPolarHBondContact O-CB 2.93Å; A442-L446 PolarHBondContact O-N 2.87Å; V443-L446 PolarHBondContact O-N 3.03Å; L446-G449 PolarHBondContact O-N 3.38Å; L446-L450 HydrophobicContact CD1-CD1 4.18Å; L446-L450 HydrophobicContact CD1-CG 4.39Å; L446-L450 HydrophobicContact CG-CD1 4.08Å; L446-L450 WeakPolarHBondContact O-CG 3.42Å; L446-L450 PolarHBondContact O-N 3.36Å
447	G	98.2	Very high	95.9	Very high	33 Å²	33	33.6 Å²	33.6	34%	0.34	19%	0.188	S	C	.	.	H	α-helix	trans	-59.9	-49	178.3	0	0	0	0	0	112.5	V443 A444 G445 G449 L450 V451	V443-G447 PolarHBondContact O-N 3.16Å; A444-G447 PolarHBondContact O-N 3.31Å; G445-G447 VanDerWaalsContact C-N 3.34Å; G445-G447 PolarHBondContact O-N 2.89Å; G447-G449 VanDerWaalsContact C-N 3.34Å; G447-G449 PolarHBondContact O-N 2.9Å; G447-L450 PolarHBondContact O-N 2.86Å; G447-V451 VanDerWaalsContact O-CG2 3.32Å; G447-V451 WeakPolarHBondContact O-CG2 3.2Å; G447-V451 PolarHBondContact O-N 3.12Å
448	A	98.3	Very high	95.6	Very high	31 Å²	31	38.1 Å²	38.1	26%	0.256	21%	0.211	S	C	.	.	H	α-helix	trans	-63.7	-39.1	177.3	0	0	0	0	0	112.4	A444 G445 V451 G452 I515 V519	A444-A448 WeakPolarHBondContact O-CB 3.39Å; A444-A448 PolarHBondContact O-N 3.28Å; G445-A448 PolarHBondContact O-N 3.41Å; A448-V451 PolarHBondContact O-N 2.77Å; A448-G452 PolarHBondContact O-N 3.1Å; A448-I515 HydrophobicContact CB-CG2 3.91Å; A448-V519 HydrophobicContact CB-CB 4.13Å; A448-V519 HydrophobicContact CB-CG1 3.88Å; A448-V519 HydrophobicContact CB-CG2 3.91Å
449	G	97.8	Very high	95.1	Very high	0 Å²	0	37.8 Å²	37.8	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-62.2	-44.6	176.1	0	0	0	0	0	112.4	G445 L446 G447 A453	G445-G449 PolarHBondContact O-N 3.36Å; L446-G449 PolarHBondContact O-N 3.38Å; G447-G449 VanDerWaalsContact C-N 3.34Å; G447-G449 PolarHBondContact O-N 2.9Å; G449-A453 WeakPolarHBondContact O-CB 3.26Å; G449-A453 PolarHBondContact O-N 2.68Å
450	L	97.6	Very high	94.5	Very high	32 Å²	32	37.1 Å²	37.1	17%	0.168	21%	0.207	C	C	.	.	H	α-helix	trans	-64.4	-47.4	175.1	-73.1	167.3	0	0	0	111.5	T133 V420 P423 L446 G447 G452 A453 F454	T133-L450 HydrophobicContact CG2-CD1 4.09Å; T133-L450 HydrophobicContact CG2-CD2 3.75Å; T133-L450 HydrophobicContact CG2-CG 4.45Å; V420-L450 HydrophobicContact CG1-CD2 4.31Å; P423-L450 HydrophobicContact CB-CD2 4.07Å; P423-L450 HydrophobicContact CB-CG 4.06Å; P423-L450 HydrophobicContact CG-CD2 3.88Å; P423-L450 HydrophobicContact CG-CG 4.17Å; L446-L450 HydrophobicContact CD1-CD1 4.18Å; L446-L450 HydrophobicContact CD1-CG 4.39Å; L446-L450 HydrophobicContact CG-CD1 4.08Å; L446-L450 WeakPolarHBondContact O-CG 3.42Å; L446-L450 PolarHBondContact O-N 3.36Å; G447-L450 PolarHBondContact O-N 2.86Å; L450-G452 PolarHBondContact O-N 3.47Å; L450-A453 PolarHBondContact O-N 3.47Å; L450-F454 HydrophobicContact CB-CD2 4.4Å; L450-F454 HydrophobicContact CB-CE2 4.34Å; L450-F454 HydrophobicContact CD2-CE2 4.04Å; L450-F454 WeakPolarHBondContact O-CD2 3.49Å; L450-F454 PolarHBondContact O-N 3.4Å
451	V	97.4	Very high	93.6	Very high	103 Å²	103	33.5 Å²	33.5	62%	0.624	19%	0.193	S	C	*	.	H	α-helix	trans	-58.4	-48.1	177.5	170	0	0	0	0	110.9	G447 A448 A453 F454 W455	G447-V451 VanDerWaalsContact O-CG2 3.32Å; G447-V451 WeakPolarHBondContact O-CG2 3.2Å; G447-V451 PolarHBondContact O-N 3.12Å; A448-V451 PolarHBondContact O-N 2.77Å; V451-A453 PolarHBondContact O-N 2.94Å; V451-F454 PolarHBondContact O-N 3.03Å; V451-W455 WeakPolarHBondContact O-CB 3.22Å; V451-W455 PolarHBondContact O-N 3.39Å
452	G	95.5	Very high	92.8	Very high	15 Å²	15	38.9 Å²	38.9	16%	0.155	23%	0.226	C	C	.	.	H	α-helix	trans	-62.4	-41	177.5	0	0	0	0	0	112.8	A448 L450 V456	A448-G452 PolarHBondContact O-N 3.1Å; L450-G452 PolarHBondContact O-N 3.47Å; G452-V456 WeakPolarHBondContact O-CG2 3.36Å; G452-V456 PolarHBondContact O-N 3.45Å; G452-V456 VanDerWaalsContact O-N 3.1Å
453	A	94.4	Very high	91.5	Very high	2 Å²	2	41 Å²	41	2%	0.017	24%	0.239	C	C	.	.	H	α-helix	trans	-64.5	-48.9	177.7	0	0	0	0	0	112.8	M419 P423 G449 L450 V451 W455 V456 G457	M419-A453 HydrophobicContact CB-CB 4.18Å; M419-A453 WeakPolarHBondContact O-CB 3.48Å; P423-A453 HydrophobicContact CG-CB 4.38Å; G449-A453 WeakPolarHBondContact O-CB 3.26Å; G449-A453 PolarHBondContact O-N 2.68Å; L450-A453 PolarHBondContact O-N 3.47Å; V451-A453 PolarHBondContact O-N 2.94Å; A453-W455 VanDerWaalsContact C-N 3.35Å; A453-V456 PolarHBondContact O-N 3.44Å; A453-G457 PolarHBondContact O-N 3.12Å
454	F	94.2	Very high	89.7	Confident	62 Å²	62	45 Å²	45	27%	0.272	25%	0.248	S	C	.	.	H	α-helix	trans	-66.9	-36.9	177.4	-74.6	-64.7	0	0	0	111.9	F136 V420 L450 V451 G457 I458	F136-F454 HydrophobicContact CD1-CZ 4.5Å; F136-F454 HydrophobicContact CE1-CE1 4.15Å; F136-F454 AromaticContact CE1-CZ 3.59Å; F136-F454 HydrophobicContact CE1-CZ 3.59Å; F136-F454 HydrophobicContact CZ-CE1 4.42Å; F136-F454 HydrophobicContact CZ-CZ 4.07Å; V420-F454 HydrophobicContact CG2-CE1 4.47Å; V420-F454 HydrophobicContact CG2-CZ 4.02Å; L450-F454 HydrophobicContact CB-CD2 4.4Å; L450-F454 HydrophobicContact CB-CE2 4.34Å; L450-F454 HydrophobicContact CD2-CE2 4.04Å; L450-F454 WeakPolarHBondContact O-CD2 3.49Å; L450-F454 PolarHBondContact O-N 3.4Å; V451-F454 PolarHBondContact O-N 3.03Å; F454-G457 PolarHBondContact O-N 3.48Å; F454-I458 HydrophobicContact CB-CD1 4.14Å; F454-I458 HydrophobicContact CD1-CD1 4.39Å; F454-I458 WeakPolarHBondContact O-CB 3.48Å; F454-I458 VanDerWaalsContact O-CG1 3.25Å; F454-I458 WeakPolarHBondContact O-CG1 3.45Å; F454-I458 PolarHBondContact O-N 3.06Å
455	W	93.1	Very high	87	Confident	147 Å²	147	47.1 Å²	47.1	56%	0.557	26%	0.26	S	S	*	.	H	α-helix	trans	-57.9	-50.3	175.3	179.3	-77.1	0	0	0	111.7	V451 A453 G459 F500 Y501	V451-W455 WeakPolarHBondContact O-CB 3.22Å; V451-W455 PolarHBondContact O-N 3.39Å; A453-W455 VanDerWaalsContact C-N 3.35Å; W455-G459 WeakPolarHBondContact O-CA 3.37Å; W455-G459 PolarHBondContact O-N 3.37Å; W455-F500 AromaticContact CD1-CE1 3.68Å; W455-F500 AromaticContact NE1-CE1 3.83Å; W455-Y501 AromaticContact CD1-CE1 3.84Å; W455-Y501 AromaticContact NE1-CE1 3.59Å; W455-Y501 AromaticContact NE1-CZ 3.93Å; W455-Y501 PolarHBondContact NE1-OH 3.13Å
456	V	90.5	Very high	84.4	Confident	1 Å²	1	52.9 Å²	52.9	1%	0.006	30%	0.301	C	S	.	.	H	α-helix	trans	-68.7	-45.7	178.9	175.6	0	0	0	0	111.1	G452 A453 G459 S460 F500 L503 Y508 F511	G452-V456 WeakPolarHBondContact O-CG2 3.36Å; G452-V456 PolarHBondContact O-N 3.45Å; G452-V456 VanDerWaalsContact O-N 3.1Å; A453-V456 PolarHBondContact O-N 3.44Å; V456-G459 PolarHBondContact O-N 3.42Å; V456-S460 PolarHBondContact O-N 3.11Å; V456-F500 HydrophobicContact CG2-CD1 4.26Å; V456-F500 HydrophobicContact CG2-CE1 3.41Å; V456-F500 VanDerWaalsContact CG2-CE1 3.41Å; V456-F500 HydrophobicContact CG2-CE2 4.15Å; V456-F500 HydrophobicContact CG2-CZ 3.34Å; V456-L503 HydrophobicContact CG1-CB 4.3Å; V456-L503 HydrophobicContact CG1-CD2 4.15Å; V456-Y508 HydrophobicContact CG1-CD1 4.16Å; V456-Y508 HydrophobicContact CG1-CE1 3.58Å; V456-F511 HydrophobicContact CG2-CD1 4.35Å; V456-F511 HydrophobicContact CG2-CE1 3.64Å; V456-F511 HydrophobicContact CG2-CZ 4.09Å
457	G	88	Confident	81.6	Confident	0 Å²	0	55.4 Å²	55.4	0%	0	33%	0.328	C	S	.	.	H	α-helix	trans	-66.5	-49.3	-175.7	0	0	0	0	0	113.6	M419 A453 F454 G459 S460 I461	M419-G457 VanDerWaalsContact SD-CA 3.59Å; A453-G457 PolarHBondContact O-N 3.12Å; F454-G457 PolarHBondContact O-N 3.48Å; G457-G459 VanDerWaalsContact C-N 3.35Å; G457-S460 PolarHBondContact O-N 3.46Å; G457-S460 PolarHBondContact O-OG 3.35Å; G457-I461 WeakPolarHBondContact O-CG1 3.36Å; G457-I461 PolarHBondContact O-N 3.4Å
458	I	86.9	Confident	79.2	Confident	95 Å²	95	56.6 Å²	56.6	49%	0.487	34%	0.335	S	S	.	.	H	α-helix	trans	-65.6	-42.2	174.9	-62.1	171.1	0	0	0	109.6	F454 S460 I461 V462	F454-I458 HydrophobicContact CB-CD1 4.14Å; F454-I458 HydrophobicContact CD1-CD1 4.39Å; F454-I458 WeakPolarHBondContact O-CB 3.48Å; F454-I458 VanDerWaalsContact O-CG1 3.25Å; F454-I458 WeakPolarHBondContact O-CG1 3.45Å; F454-I458 PolarHBondContact O-N 3.06Å; I458-S460 VanDerWaalsContact C-N 3.29Å; I458-S460 PolarHBondContact O-N 3.46Å; I458-I461 PolarHBondContact O-N 3.35Å; I458-V462 HydrophobicContact CG2-CG2 4.05Å; I458-V462 WeakPolarHBondContact O-CG2 3.47Å; I458-V462 PolarHBondContact O-N 3.38Å
459	G	84.8	Confident	76.9	Confident	8 Å²	8	61.5 Å²	61.5	8%	0.082	35%	0.35	C	S	.	.	H	α-helix	trans	-51.2	-47.9	173.4	0	0	0	0	0	112.1	W455 V456 G457 I461 V462 T463	W455-G459 WeakPolarHBondContact O-CA 3.37Å; W455-G459 PolarHBondContact O-N 3.37Å; V456-G459 PolarHBondContact O-N 3.42Å; G457-G459 VanDerWaalsContact C-N 3.35Å; G459-I461 VanDerWaalsContact C-N 3.27Å; G459-I461 PolarHBondContact O-N 3.31Å; G459-V462 PolarHBondContact O-N 3.1Å; G459-T463 PolarHBondContact O-N 3.27Å; G459-T463 PolarHBondContact O-OG1 3.49Å
460	S	82.3	Confident	74.9	Confident	16 Å²	16	69 Å²	69	11%	0.112	38%	0.378	C	S	.	.	H	α-helix	trans	-61.3	-30.3	177	83.2	0	0	0	0	114.6	V456 G457 I458 Y501 Y508	V456-S460 PolarHBondContact O-N 3.11Å; G457-S460 PolarHBondContact O-N 3.46Å; G457-S460 PolarHBondContact O-OG 3.35Å; I458-S460 VanDerWaalsContact C-N 3.29Å; I458-S460 PolarHBondContact O-N 3.46Å; S460-Y501 WeakPolarHBondContact CB-O 3.28Å; S460-Y508 WeakPolarHBondContact CB-OH 3.42Å; S460-Y508 PolarHBondContact OG-OH 2.84Å; S460-Y508 VanDerWaalsContact OG-OH 3.12Å
461	I	78.8	Confident	72.9	Confident	64 Å²	64	70 Å²	70	33%	0.328	38%	0.384	S	S	.	.	H	α-helix	trans	-79.2	-39.9	179.7	-65.8	166.6	0	0	0	109.8	G457 I458 G459 R464	G457-I461 WeakPolarHBondContact O-CG1 3.36Å; G457-I461 PolarHBondContact O-N 3.4Å; I458-I461 PolarHBondContact O-N 3.35Å; G459-I461 VanDerWaalsContact C-N 3.27Å; G459-I461 PolarHBondContact O-N 3.31Å; I461-R464 WeakPolarHBondContact O-CG 3.49Å
462	V	79.6	Confident	71.1	Confident	112 Å²	112	67.8 Å²	67.8	68%	0.679	37%	0.371	S	S	*	.	H	α-helix	trans	-73.8	-47.3	-179.2	175	0	0	0	0	111	I458 G459 R464	I458-V462 HydrophobicContact CG2-CG2 4.05Å; I458-V462 WeakPolarHBondContact O-CG2 3.47Å; I458-V462 PolarHBondContact O-N 3.38Å; G459-V462 PolarHBondContact O-N 3.1Å; V462-R464 PolarHBondContact O-N 2.79Å; V462-R464 VanDerWaalsContact O-N 3.09Å
463	T	71.3	Confident	69.3	Low	45 Å²	45	69 Å²	69	28%	0.276	38%	0.377	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.2	38	-179.9	64.6	0	0	0	0	112	G459 S465 Y501	G459-T463 PolarHBondContact O-N 3.27Å; G459-T463 PolarHBondContact O-OG1 3.49Å; T463-S465 PolarHBondContact O-N 3.36Å; T463-Y501 HydrophobicContact CG2-CD2 3.52Å; T463-Y501 HydrophobicContact CG2-CE2 3.98Å; T463-Y501 HydrophobicContact CG2-CG 4.46Å; T463-Y501 VanDerWaalsContact OG1-CB 3.25Å; T463-Y501 WeakPolarHBondContact OG1-CB 3.24Å
464	R	59.9	Low	67.8	Low	138 Å²	138	71.2 Å²	71.2	52%	0.521	39%	0.392	S	S	.	.			trans	-52.4	85.3	175.4	-94.6	177.4	-177.6	171.2	5.9	109.9	M405 D407 I461 V462	M405-R464 PolarHBondContact O-NH2 3.3Å; M405-R464 VanDerWaalsContact O-NH2 3.12Å; D407-R464 IonicContact OD1-CZ 2.66Å; D407-R464 IonicContact OD1-NE 3.71Å; D407-R464 IonicContact OD1-NH2 3.07Å; D407-R464 PolarHBondContact OD1-NH2 3.48Å; D407-R464 VanDerWaalsContact OD1-NH2 3.17Å; D407-R464 IonicContact OD2-CZ 3.1Å; D407-R464 IonicContact OD2-NE 3.17Å; D407-R464 IonicContact OD2-NH2 3.72Å; D407-R464 PolarHBondContact OD2-NH2 3.11Å; I461-R464 WeakPolarHBondContact O-CG 3.49Å; V462-R464 PolarHBondContact O-N 2.79Å; V462-R464 VanDerWaalsContact O-N 3.09Å
465	S	42.6	Very low	66.3	Low	80 Å²	80	69.7 Å²	69.7	56%	0.559	39%	0.389	S	S	*	.			trans	-82.7	123.1	161.7	-171.1	0	0	0	0	105.1	T463 G467 H498	T463-S465 PolarHBondContact O-N 3.36Å; S465-G467 PolarHBondContact O-N 2.74Å; S465-H498 WeakPolarHBondContact CB-CE1 3.22Å; S465-H498 VanDerWaalsContact CB-NE2 3.31Å; S465-H498 WeakPolarHBondContact CB-NE2 3.32Å
466	S	42.3	Very low	64.8	Low	121 Å²	121	68.3 Å²	68.3	85%	0.846	39%	0.388	S	S	*	.			trans	-63.5	39.4	-178.4	-52.4	0	0	0	0	113.5
467	G	40.7	Very low	63.4	Low	58 Å²	58	70.3 Å²	70.3	60%	0.598	40%	0.398	S	S	*	.			trans	-79.9	-17.9	-161.1	0	0	0	0	0	116.1	S465 K469	S465-G467 PolarHBondContact O-N 2.74Å; G467-K469 PolarHBondContact O-N 3.09Å
468	A	46.7	Very low	61.9	Low	59 Å²	59	75.9 Å²	75.9	49%	0.488	43%	0.428	S	S	.	.			trans	-80.7	88.1	171.5	0	0	0	0	0	109.1	R470	A468-R470 PolarHBondContact O-N 3.3Å
469	K	51.1	Low	60.3	Low	134 Å²	134	77.4 Å²	77.4	58%	0.583	44%	0.442	S	S	*	.	P	Polyproline II helix	trans	-60.6	119.4	168.4	-76.2	-179.6	-178.9	172.1	0	108.1	G467	G467-K469 PolarHBondContact O-N 3.09Å
470	R	56.3	Low	58.8	Low	156 Å²	156	81.8 Å²	81.8	59%	0.589	47%	0.468	S	S	*	.	P	Polyproline II helix	trans	-59.5	139.7	178.8	-58	174.4	-168.9	173.7	2.4	108.5	S310 A468	S310-R470 PolarHBondContact OG-NH1 3.21Å; S310-R470 VanDerWaalsContact OG-NH1 3.09Å; A468-R470 PolarHBondContact O-N 3.3Å
471	L	54.8	Low	57.4	Low	54 Å²	54	83.2 Å²	83.2	28%	0.283	48%	0.48	S	S	.	.	P	Polyproline II helix	trans	-62.6	128.9	165.6	-87.6	100.9	0	0	0	107.7	R225	R225-L471 PolarHBondContact NH2-O 2.94Å; R225-L471 VanDerWaalsContact NH2-O 3.09Å
472	P	59.1	Low	56.1	Low	56 Å²	56	82.3 Å²	82.3	36%	0.364	48%	0.482	S	S	.	.	P	Polyproline II helix	trans	-56.2	143.2	-178.1	21.8	-31.3	0	0	0	109.7	R225 S474	R225-P472 PolarHBondContact NH2-O 3.46Å; P472-S474 PolarHBondContact O-N 3.05Å
473	P	58.4	Low	54.6	Low	41 Å²	41	83.9 Å²	83.9	27%	0.266	48%	0.48	S	S	.	.			trans	-74.5	44.3	176.4	34	-35.6	0	0	0	110.2	G306	G306-P473 WeakPolarHBondContact CA-O 3.24Å; G306-P473 PolarHBondContact N-O 3.26Å
474	S	63.5	Low	53.6	Low	49 Å²	49	88.6 Å²	88.6	34%	0.343	50%	0.499	S	S	.	.			trans	-96.6	133.4	-179.6	-58.2	0	0	0	0	110.2	P472 H476	P472-S474 PolarHBondContact O-N 3.05Å; S474-H476 WeakPolarHBondContact CB-O 3.3Å; S474-H476 PolarHBondContact O-N 3.4Å
475	C	61.2	Low	53.2	Low	29 Å²	29	85.1 Å²	85.1	20%	0.196	49%	0.493	C	S	.	.	S	Bend	trans	-69.3	-19.8	172.3	-56	0	0	0	0	112.4	E222 G223 C305	E222-C475 CarbonylContact C-O 3.37Å; E222-C475 VanDerWaalsContact C-O 3.28Å; E222-C475 WeakPolarHBondContact CB-O 3.23Å; G223-C475 PolarHBondContact N-O 3.12Å; C305-C475 HydrophobicContact CB-CB 3.98Å; C305-C475 WeakPolarHBondContact CB-SG 3.27Å; C305-C475 PolarHBondContact O-SG 2.95Å; C305-C475 WeakPolarHBondContact SG-CB 3.47Å; C305-C475 CovalentContact SG-SG 2.04Å; C305-C475 PolarHBondContact SG-SG 3.39Å
476	H	62.3	Low	53.5	Low	118 Å²	118	83.9 Å²	83.9	55%	0.546	49%	0.488	S	S	.	.			trans	-130.4	122.4	177	-59.8	-69	0	0	0	109	E222 S474	E222-H476 IonicContact OE2-CE1 3.9Å; E222-H476 PolarHBondContact OE2-CE1 2.85Å; E222-H476 IonicContact OE2-ND1 2.7Å; E222-H476 IonicContact OE2-NE2 3.46Å; S474-H476 WeakPolarHBondContact CB-O 3.3Å; S474-H476 PolarHBondContact O-N 3.4Å
477	I	60.8	Low	53.7	Low	43 Å²	43	82.4 Å²	82.4	22%	0.221	47%	0.47	C	S	.	.			trans	-100.2	107.1	169.4	-59.4	179	0	0	0	107	N224 T479 A482	N224-I477 HydrophobicContact CB-CD1 4.05Å; I477-T479 PolarHBondContact O-N 3.45Å; I477-A482 HydrophobicContact CG2-CB 3.85Å
478	N	57.1	Low	54	Low	118 Å²	118	80.6 Å²	80.6	63%	0.631	45%	0.451	S	S	*	.			trans	-61	133.5	167.2	-83.6	-6.2	0	0	0	108.6	T480 A481 A482	N478-T480 PolarHBondContact O-N 2.9Å; N478-A481 WeakPolarHBondContact O-CB 3.34Å; N478-A481 PolarHBondContact O-N 2.89Å; N478-A482 PolarHBondContact O-N 3.38Å
479	T	53.7	Low	54	Low	127 Å²	127	82.4 Å²	82.4	78%	0.779	45%	0.452	S	S	*	.	H	α-helix	trans	-51.3	-29.9	-177.4	-14.5	0	0	0	0	112.5	I477 F483	I477-T479 PolarHBondContact O-N 3.45Å; T479-F483 WeakPolarHBondContact O-CB 3.26Å; T479-F483 PolarHBondContact O-N 2.69Å
480	T	53.3	Low	53.8	Low	100 Å²	100	81 Å²	81	61%	0.613	46%	0.455	S	S	*	.	H	α-helix	trans	-67	-38.5	175.8	-13.2	0	0	0	0	113.7	N478 F483 Q484	N478-T480 PolarHBondContact O-N 2.9Å; T480-F483 PolarHBondContact O-N 3.3Å; T480-Q484 WeakPolarHBondContact O-CG 3.38Å; T480-Q484 PolarHBondContact O-N 2.69Å
481	A	52	Low	53.1	Low	46 Å²	46	79.3 Å²	79.3	38%	0.38	46%	0.462	S	S	.	.	H	α-helix	trans	-74	-36.2	177.6	0	0	0	0	0	111.7	N478 F483 T485	N478-A481 WeakPolarHBondContact O-CB 3.34Å; N478-A481 PolarHBondContact O-N 2.89Å; A481-F483 VanDerWaalsContact C-N 3.32Å; A481-T485 PolarHBondContact O-N 2.86Å; A481-T485 PolarHBondContact O-OG1 3.23Å
482	A	50.9	Low	52.9	Low	44 Å²	44	81.1 Å²	81.1	36%	0.364	48%	0.479	S	S	.	.	H	α-helix	trans	-61.6	-42	170.7	0	0	0	0	0	111.4	I477 N478 T485 A486	I477-A482 HydrophobicContact CG2-CB 3.85Å; N478-A482 PolarHBondContact O-N 3.38Å; A482-T485 PolarHBondContact O-N 2.88Å; A482-A486 WeakPolarHBondContact O-CB 3.27Å; A482-A486 PolarHBondContact O-N 3.41Å
483	F	49.8	Very low	52.9	Low	145 Å²	145	86.4 Å²	86.4	64%	0.636	49%	0.492	S	S	*	.	H	α-helix	trans	-68	-41.7	178.7	-157.9	-106.1	0	0	0	112.7	T479 T480 A481 T485 A486 I487	T479-F483 WeakPolarHBondContact O-CB 3.26Å; T479-F483 PolarHBondContact O-N 2.69Å; T480-F483 PolarHBondContact O-N 3.3Å; A481-F483 VanDerWaalsContact C-N 3.32Å; F483-T485 VanDerWaalsContact C-N 3.32Å; F483-T485 PolarHBondContact O-N 3.49Å; F483-A486 PolarHBondContact O-N 2.92Å; F483-I487 HydrophobicContact CD1-CD1 3.48Å; F483-I487 VanDerWaalsContact CD1-CD1 3.48Å; F483-I487 HydrophobicContact CD1-CG1 4.32Å; F483-I487 HydrophobicContact CE1-CD1 3.44Å; F483-I487 VanDerWaalsContact CE1-CD1 3.44Å; F483-I487 HydrophobicContact CE1-CG1 4.28Å; F483-I487 HydrophobicContact CG-CD1 4.43Å; F483-I487 HydrophobicContact CZ-CD1 4.33Å; F483-I487 WeakPolarHBondContact O-CG1 3.27Å; F483-I487 PolarHBondContact O-N 3.2Å
484	Q	49.3	Very low	53.1	Low	144 Å²	144	86.8 Å²	86.8	67%	0.673	49%	0.494	S	S	*	.	H	α-helix	trans	-62.6	-37.7	173.6	-78.9	-178.6	-21.2	0	0	112.6	T480 G488	T480-Q484 WeakPolarHBondContact O-CG 3.38Å; T480-Q484 PolarHBondContact O-N 2.69Å; Q484-G488 PolarHBondContact O-N 3.27Å; Q484-G488 VanDerWaalsContact O-N 3.15Å
485	T	51.7	Low	53.5	Low	65 Å²	65	90.1 Å²	90.1	40%	0.399	51%	0.513	S	S	.	.	H	α-helix	trans	-67.3	-40.1	175.3	-48.7	0	0	0	0	111.2	A481 A482 F483 G488 N489	A481-T485 PolarHBondContact O-N 2.86Å; A481-T485 PolarHBondContact O-OG1 3.23Å; A482-T485 PolarHBondContact O-N 2.88Å; F483-T485 VanDerWaalsContact C-N 3.32Å; F483-T485 PolarHBondContact O-N 3.49Å; T485-G488 PolarHBondContact O-N 2.85Å; T485-N489 PolarHBondContact O-N 3.35Å
486	A	48.8	Very low	54.3	Low	54 Å²	54	91.8 Å²	91.8	45%	0.446	53%	0.534	S	S	.	.	H	α-helix	trans	-65.7	-40	177.2	0	0	0	0	0	113	A482 F483 N489	A482-A486 WeakPolarHBondContact O-CB 3.27Å; A482-A486 PolarHBondContact O-N 3.41Å; F483-A486 PolarHBondContact O-N 2.92Å; A486-N489 PolarHBondContact O-N 2.86Å
487	I	46	Very low	55.1	Low	91 Å²	91	90.7 Å²	90.7	47%	0.467	53%	0.532	S	S	.	.	H	α-helix	trans	-68	-36.9	177	-67.5	167.1	0	0	0	111.4	F483 N489 V490	F483-I487 HydrophobicContact CD1-CD1 3.48Å; F483-I487 VanDerWaalsContact CD1-CD1 3.48Å; F483-I487 HydrophobicContact CD1-CG1 4.32Å; F483-I487 HydrophobicContact CE1-CD1 3.44Å; F483-I487 VanDerWaalsContact CE1-CD1 3.44Å; F483-I487 HydrophobicContact CE1-CG1 4.28Å; F483-I487 HydrophobicContact CG-CD1 4.43Å; F483-I487 HydrophobicContact CZ-CD1 4.33Å; F483-I487 WeakPolarHBondContact O-CG1 3.27Å; F483-I487 PolarHBondContact O-N 3.2Å; I487-N489 PolarHBondContact O-N 3.23Å; I487-V490 PolarHBondContact O-N 2.65Å
488	G	47	Very low	55.8	Low	20 Å²	20	91.8 Å²	91.8	21%	0.206	54%	0.536	C	S	.	.	H	α-helix	trans	-63.4	-24.2	175.4	0	0	0	0	0	114.3	Q484 T485 T491	Q484-G488 PolarHBondContact O-N 3.27Å; Q484-G488 VanDerWaalsContact O-N 3.15Å; T485-G488 PolarHBondContact O-N 2.85Å; G488-T491 PolarHBondContact O-OG1 3.3Å
489	N	46.4	Very low	56.9	Low	97 Å²	97	91.5 Å²	91.5	52%	0.519	53%	0.526	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.9	-18.9	178.1	-79.1	-1.8	0	0	0	113.5	T485 A486 I487	T485-N489 PolarHBondContact O-N 3.35Å; A486-N489 PolarHBondContact O-N 2.86Å; I487-N489 PolarHBondContact O-N 3.23Å
490	V	47	Very low	58.2	Low	105 Å²	105	89.1 Å²	89.1	64%	0.636	51%	0.505	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.8	-24.7	-178.3	-176.8	0	0	0	0	111.8	I487	I487-V490 PolarHBondContact O-N 2.65Å
491	T	43.3	Very low	59.7	Low	120 Å²	120	85.9 Å²	85.9	74%	0.736	48%	0.482	S	S	*	.	S	Bend	trans	-92.7	-9.8	-167.7	44.1	0	0	0	0	115.5	G488	G488-T491 PolarHBondContact O-OG1 3.3Å
492	S	50.5	Low	61.2	Low	91 Å²	91	85.5 Å²	85.5	64%	0.636	48%	0.476	S	S	*	.			trans	-135.2	57.5	-179.1	69.3	0	0	0	0	113	P494	S492-P494 WeakPolarHBondContact O-CD 3.46Å
493	R	58.9	Low	62.9	Low	167 Å²	167	84.6 Å²	84.6	63%	0.63	47%	0.465	S	S	*	.			trans	-73.5	120.4	169.8	-73.9	-175.2	176.9	179.3	-2.2	109.2	T495	R493-T495 PolarHBondContact O-N 3.4Å
494	P	62.9	Low	64.7	Low	49 Å²	49	77.9 Å²	77.9	32%	0.318	44%	0.437	S	S	.	.			trans	-60.7	137	176.2	23.4	-30.6	0	0	0	110	S492 H498 R499	S492-P494 WeakPolarHBondContact O-CD 3.46Å; P494-H498 HydrophobicContact CB-CB 4.11Å; P494-H498 WeakPolarHBondContact CB-ND1 3.32Å; P494-R499 WeakPolarHBondContact O-CB 3.1Å
495	T	70.7	Confident	66.6	Low	120 Å²	120	71.8 Å²	71.8	74%	0.736	41%	0.408	S	S	*	.			trans	-110.8	157.7	-179.8	51.5	0	0	0	0	111.1	R493	R493-T495 PolarHBondContact O-N 3.4Å
496	G	77.6	Confident	68.6	Low	63 Å²	63	68.9 Å²	68.9	65%	0.649	39%	0.389	S	S	*	.	T	Hydrogen-bonded Turn	trans	62.8	-137.2	177.2	0	0	0	0	0	114.1	H498 R499 F500	G496-H498 PolarHBondContact O-N 2.97Å; G496-R499 WeakPolarHBondContact O-CB 3.28Å; G496-R499 PolarHBondContact O-N 2.97Å; G496-F500 PolarHBondContact O-N 3.38Å
497	L	79.6	Confident	70.7	Confident	96 Å²	96	68.7 Å²	68.7	50%	0.503	38%	0.377	S	S	.	.	H	α-helix	trans	-62.5	-28.9	-175	-166.9	66.6	0	0	0	112.8	R499 F500 Y501	L497-R499 VanDerWaalsContact C-N 3.3Å; L497-R499 PolarHBondContact O-N 2.89Å; L497-F500 HydrophobicContact CD1-CD1 4.31Å; L497-F500 WeakPolarHBondContact O-CB 3.3Å; L497-F500 PolarHBondContact O-N 3.44Å; L497-Y501 HydrophobicContact CD1-CE1 4.41Å; L497-Y501 HydrophobicContact CD1-CE2 4.21Å; L497-Y501 HydrophobicContact CD2-CE2 3.64Å; L497-Y501 WeakPolarHBondContact CD2-OH 3.41Å; L497-Y501 HydrophobicContact CG-CD2 4.12Å; L497-Y501 HydrophobicContact CG-CE1 4.48Å; L497-Y501 HydrophobicContact CG-CE2 3.44Å; L497-Y501 VanDerWaalsContact CG-CE2 3.44Å; L497-Y501 WeakPolarHBondContact O-CD2 3.3Å; L497-Y501 PolarHBondContact O-N 3.09Å
498	H	75.6	Confident	73	Confident	66 Å²	66	64.7 Å²	64.7	31%	0.306	36%	0.356	S	S	.	.	H	α-helix	trans	-67.1	-31.6	175.9	-165.5	-60.7	0	0	0	112.2	S465 P494 G496 F500 S502	S465-H498 WeakPolarHBondContact CB-CE1 3.22Å; S465-H498 VanDerWaalsContact CB-NE2 3.31Å; S465-H498 WeakPolarHBondContact CB-NE2 3.32Å; P494-H498 HydrophobicContact CB-CB 4.11Å; P494-H498 WeakPolarHBondContact CB-ND1 3.32Å; G496-H498 PolarHBondContact O-N 2.97Å; H498-F500 VanDerWaalsContact C-N 3.33Å; H498-S502 PolarHBondContact O-N 3.28Å; H498-S502 VanDerWaalsContact O-N 3.1Å; H498-S502 PolarHBondContact O-OG 3.45Å
499	R	79.1	Confident	75.3	Confident	112 Å²	112	63.8 Å²	63.8	42%	0.423	35%	0.347	S	S	.	.	H	α-helix	trans	-67.7	-37.7	172.8	-165.7	172.2	-177.4	-179.1	2.1	111.5	D234 T236 P494 G496 L497 S502	D234-R499 IonicContact OD1-NH2 3.91Å; D234-R499 IonicContact OD2-CZ 3.89Å; D234-R499 IonicContact OD2-NH2 2.82Å; D234-R499 PolarHBondContact OD2-NH2 3.37Å; T236-R499 HydrophobicContact CG2-CG 3.83Å; T236-R499 WeakPolarHBondContact CG2-O 3.29Å; P494-R499 WeakPolarHBondContact O-CB 3.1Å; G496-R499 WeakPolarHBondContact O-CB 3.28Å; G496-R499 PolarHBondContact O-N 2.97Å; L497-R499 VanDerWaalsContact C-N 3.3Å; L497-R499 PolarHBondContact O-N 2.89Å; R499-S502 VanDerWaalsContact C-OG 3.27Å; R499-S502 VanDerWaalsContact CA-OG 3.26Å; R499-S502 WeakPolarHBondContact CA-OG 3.17Å; R499-S502 PolarHBondContact O-N 3.03Å; R499-S502 PolarHBondContact O-OG 3.17Å
500	F	82.8	Confident	77.7	Confident	76 Å²	76	59.2 Å²	59.2	33%	0.333	32%	0.323	S	S	.	.	H	α-helix	trans	-65.6	-40.5	177.4	-175.2	-115.5	0	0	0	111.9	W455 V456 G496 L497 H498 S502 L503 F511	W455-F500 AromaticContact CD1-CE1 3.68Å; W455-F500 AromaticContact NE1-CE1 3.83Å; V456-F500 HydrophobicContact CG2-CD1 4.26Å; V456-F500 HydrophobicContact CG2-CE1 3.41Å; V456-F500 VanDerWaalsContact CG2-CE1 3.41Å; V456-F500 HydrophobicContact CG2-CE2 4.15Å; V456-F500 HydrophobicContact CG2-CZ 3.34Å; G496-F500 PolarHBondContact O-N 3.38Å; L497-F500 HydrophobicContact CD1-CD1 4.31Å; L497-F500 WeakPolarHBondContact O-CB 3.3Å; L497-F500 PolarHBondContact O-N 3.44Å; H498-F500 VanDerWaalsContact C-N 3.33Å; F500-S502 VanDerWaalsContact C-N 3.28Å; F500-S502 PolarHBondContact O-N 3.49Å; F500-L503 WeakPolarHBondContact O-CB 3.49Å; F500-L503 PolarHBondContact O-N 3.45Å; F500-F511 HydrophobicContact CE2-CE2 4.32Å; F500-F511 HydrophobicContact CE2-CZ 4.16Å; F500-F511 HydrophobicContact CZ-CE2 4.46Å; F500-F511 AromaticContact CZ-CZ 3.86Å; F500-F511 HydrophobicContact CZ-CZ 3.86Å
501	Y	84.2	Confident	80	Confident	33 Å²	33	56.9 Å²	56.9	13%	0.129	30%	0.304	C	S	.	.	H	α-helix	trans	-74.3	-16	174.7	-60	-37.5	0	0	0	114.4	W455 S460 T463 L497 L503	W455-Y501 AromaticContact CD1-CE1 3.84Å; W455-Y501 AromaticContact NE1-CE1 3.59Å; W455-Y501 AromaticContact NE1-CZ 3.93Å; W455-Y501 PolarHBondContact NE1-OH 3.13Å; S460-Y501 WeakPolarHBondContact CB-O 3.28Å; T463-Y501 HydrophobicContact CG2-CD2 3.52Å; T463-Y501 HydrophobicContact CG2-CE2 3.98Å; T463-Y501 HydrophobicContact CG2-CG 4.46Å; T463-Y501 VanDerWaalsContact OG1-CB 3.25Å; T463-Y501 WeakPolarHBondContact OG1-CB 3.24Å; L497-Y501 HydrophobicContact CD1-CE1 4.41Å; L497-Y501 HydrophobicContact CD1-CE2 4.21Å; L497-Y501 HydrophobicContact CD2-CE2 3.64Å; L497-Y501 WeakPolarHBondContact CD2-OH 3.41Å; L497-Y501 HydrophobicContact CG-CD2 4.12Å; L497-Y501 HydrophobicContact CG-CE1 4.48Å; L497-Y501 HydrophobicContact CG-CE2 3.44Å; L497-Y501 VanDerWaalsContact CG-CE2 3.44Å; L497-Y501 WeakPolarHBondContact O-CD2 3.3Å; L497-Y501 PolarHBondContact O-N 3.09Å; Y501-L503 PolarHBondContact O-N 3.15Å
502	S	83	Confident	82.5	Confident	37 Å²	37	51.2 Å²	51.2	26%	0.259	27%	0.269	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.4	5.3	169.5	60.2	0	0	0	0	114.1	T236 H498 R499 F500 S504	T236-S502 CarbonylContact C-O 3.51Å; T236-S502 VanDerWaalsContact CA-O 3.26Å; T236-S502 WeakPolarHBondContact CA-O 3.26Å; T236-S502 WeakPolarHBondContact CB-O 3.07Å; H498-S502 PolarHBondContact O-N 3.28Å; H498-S502 VanDerWaalsContact O-N 3.1Å; H498-S502 PolarHBondContact O-OG 3.45Å; R499-S502 VanDerWaalsContact C-OG 3.27Å; R499-S502 VanDerWaalsContact CA-OG 3.26Å; R499-S502 WeakPolarHBondContact CA-OG 3.17Å; R499-S502 PolarHBondContact O-N 3.03Å; R499-S502 PolarHBondContact O-OG 3.17Å; F500-S502 VanDerWaalsContact C-N 3.28Å; F500-S502 PolarHBondContact O-N 3.49Å; S502-S504 PolarHBondContact O-N 3.49Å
503	L	86.3	Confident	84.8	Confident	25 Å²	25	46.9 Å²	46.9	13%	0.131	24%	0.239	C	C	.	.			trans	-53.7	130.8	174.1	-174.7	71.8	0	0	0	110.5	P235 V456 F500 Y501 Y505 W507 Y508 F511	P235-L503 HydrophobicContact CB-CD1 3.86Å; P235-L503 HydrophobicContact CG-CD1 4.36Å; V456-L503 HydrophobicContact CG1-CB 4.3Å; V456-L503 HydrophobicContact CG1-CD2 4.15Å; F500-L503 WeakPolarHBondContact O-CB 3.49Å; F500-L503 PolarHBondContact O-N 3.45Å; Y501-L503 PolarHBondContact O-N 3.15Å; L503-Y505 PolarHBondContact O-N 2.81Å; L503-W507 HydrophobicContact CD1-CB 4.1Å; L503-W507 HydrophobicContact CD2-CB 4.22Å; L503-W507 HydrophobicContact CG-CB 4.11Å; L503-Y508 HydrophobicContact CB-CE1 4.33Å; L503-Y508 HydrophobicContact CD2-CD1 4.13Å; L503-Y508 HydrophobicContact CD2-CE1 4.27Å; L503-Y508 HydrophobicContact CG-CE1 4.38Å; L503-Y508 WeakPolarHBondContact O-CE1 3.3Å; L503-F511 HydrophobicContact CD2-CB 4.4Å; L503-F511 HydrophobicContact CD2-CG 4.41Å
504	S	88.7	Confident	86.6	Confident	5 Å²	5	43.2 Å²	43.2	4%	0.035	23%	0.232	C	C	.	.			trans	-57.7	134.5	177.1	176.7	0	0	0	0	110.8	P235 E237 R238 S502 M506 W507	P235-S504 WeakPolarHBondContact O-CB 3.47Å; P235-S504 PolarHBondContact O-N 3.45Å; E237-S504 VanDerWaalsContact O-CB 3.27Å; E237-S504 WeakPolarHBondContact O-CB 3.43Å; R238-S504 PolarHBondContact O-OG 2.95Å; S502-S504 PolarHBondContact O-N 3.49Å; S504-M506 PolarHBondContact O-N 3.12Å; S504-M506 VanDerWaalsContact O-N 3.07Å; S504-M506 PolarHBondContact OG-N 3.45Å; S504-W507 WeakPolarHBondContact O-CB 3.38Å; S504-W507 PolarHBondContact O-N 3.18Å
505	Y	89.1	Confident	88.2	Confident	16 Å²	16	42.5 Å²	42.5	6%	0.063	22%	0.224	C	C	.	.	G	3₁₀ helix	trans	-59.2	-22.7	178.6	61.8	-97.2	0	0	0	112.8	R238 H239 L411 L414 L503 W507 Y508	R238-Y505 HydrophobicContact CG-CE1 4.22Å; H239-Y505 PolarHBondContact CE1-OH 2.88Å; H239-Y505 AromaticContact NE2-CZ 3.58Å; H239-Y505 PolarHBondContact NE2-OH 3Å; L411-Y505 HydrophobicContact CD2-CE1 4.41Å; L411-Y505 HydrophobicContact CG-CE1 4.19Å; L414-Y505 HydrophobicContact CB-CD2 3.83Å; L414-Y505 HydrophobicContact CB-CE2 3.87Å; L414-Y505 HydrophobicContact CD1-CD2 4.34Å; L414-Y505 HydrophobicContact CD1-CE2 3.51Å; L414-Y505 HydrophobicContact CG-CE2 4.31Å; L503-Y505 PolarHBondContact O-N 2.81Å; Y505-W507 PolarHBondContact O-N 3.14Å; Y505-Y508 WeakPolarHBondContact O-CB 3.44Å; Y505-Y508 PolarHBondContact O-N 2.98Å
506	M	92.1	Very high	89.6	Confident	3 Å²	3	36.8 Å²	36.8	2%	0.015	19%	0.189	C	C	.	.	G	3₁₀ helix	trans	-66.7	-24.6	174.6	-65.4	-59.2	-61.3	0	0	112.7	I87 T243 L244 G247 L251 L414 S504	I87-M506 HydrophobicContact CD1-CE 3.85Å; I87-M506 HydrophobicContact CG1-CE 4.31Å; T243-M506 VanDerWaalsContact O-CB 3.3Å; T243-M506 WeakPolarHBondContact O-CB 3.36Å; L244-M506 HydrophobicContact CD2-CE 4.14Å; L244-M506 HydrophobicContact CD2-CG 4.15Å; L244-M506 HydrophobicContact CD2-SD 4.32Å; G247-M506 CarbonylContact C-O 3.54Å; G247-M506 WeakPolarHBondContact CA-O 3.45Å; L251-M506 HydrophobicContact CD2-CE 3.92Å; L251-M506 HydrophobicContact CD2-SD 4.4Å; L414-M506 HydrophobicContact CD1-SD 4.45Å; S504-M506 PolarHBondContact O-N 3.12Å; S504-M506 VanDerWaalsContact O-N 3.07Å; S504-M506 PolarHBondContact OG-N 3.45Å
507	W	93.9	Very high	90.5	Very high	51 Å²	51	34.9 Å²	34.9	19%	0.193	16%	0.164	C	C	.	.	G	3₁₀ helix	trans	-84.9	-10.3	176.4	-77.2	118.5	0	0	0	113.8	W242 T243 V246 L503 S504 Y505 A509 G510 F511	W242-W507 HydrophobicContact CB-CZ2 4.3Å; W242-W507 WeakPolarHBondContact O-CZ2 3.43Å; T243-W507 VanDerWaalsContact CG2-NE1 3.32Å; V246-W507 HydrophobicContact CB-CH2 3.75Å; V246-W507 HydrophobicContact CB-CZ2 4.4Å; V246-W507 HydrophobicContact CB-CZ3 4.48Å; V246-W507 HydrophobicContact CG1-CH2 3.61Å; V246-W507 HydrophobicContact CG1-CZ3 4.04Å; L503-W507 HydrophobicContact CD1-CB 4.1Å; L503-W507 HydrophobicContact CD2-CB 4.22Å; L503-W507 HydrophobicContact CG-CB 4.11Å; S504-W507 WeakPolarHBondContact O-CB 3.38Å; S504-W507 PolarHBondContact O-N 3.18Å; Y505-W507 PolarHBondContact O-N 3.14Å; W507-A509 VanDerWaalsContact C-N 3.29Å; W507-A509 PolarHBondContact O-N 2.83Å; W507-G510 PolarHBondContact O-N 3.18Å; W507-G510 VanDerWaalsContact O-N 3.15Å; W507-F511 VanDerWaalsContact O-CB 3.27Å; W507-F511 WeakPolarHBondContact O-CB 3.43Å; W507-F511 PolarHBondContact O-N 3.4Å
508	Y	94.4	Very high	91.4	Very high	6 Å²	6	35.6 Å²	35.6	2%	0.024	17%	0.168	C	C	.	.	H	α-helix	trans	-58.9	-42.1	-175.7	-71	4.9	0	0	0	112	K415 G418 M419 V456 S460 L503 Y505 S512	K415-Y508 HydrophobicContact CG-CD2 4.48Å; K415-Y508 HydrophobicContact CG-CE2 4.05Å; G418-Y508 CarbonylContact O-C 3.59Å; M419-Y508 HydrophobicContact CG-CD2 3.8Å; M419-Y508 HydrophobicContact CG-CE2 4.34Å; V456-Y508 HydrophobicContact CG1-CD1 4.16Å; V456-Y508 HydrophobicContact CG1-CE1 3.58Å; S460-Y508 WeakPolarHBondContact CB-OH 3.42Å; S460-Y508 PolarHBondContact OG-OH 2.84Å; S460-Y508 VanDerWaalsContact OG-OH 3.12Å; L503-Y508 HydrophobicContact CB-CE1 4.33Å; L503-Y508 HydrophobicContact CD2-CD1 4.13Å; L503-Y508 HydrophobicContact CD2-CE1 4.27Å; L503-Y508 HydrophobicContact CG-CE1 4.38Å; L503-Y508 WeakPolarHBondContact O-CE1 3.3Å; Y505-Y508 WeakPolarHBondContact O-CB 3.44Å; Y505-Y508 PolarHBondContact O-N 2.98Å; Y508-S512 WeakPolarHBondContact O-CB 3.49Å; Y508-S512 PolarHBondContact O-N 3.31Å; Y508-S512 PolarHBondContact O-OG 3.12Å
509	A	95.6	Very high	92.5	Very high	1 Å²	1	34.7 Å²	34.7	1%	0.008	17%	0.167	C	C	.	.	H	α-helix	trans	-62.2	-47.3	177.2	0	0	0	0	0	111.8	F250 G418 W507 S512 C513	F250-A509 HydrophobicContact CB-CB 3.81Å; G418-A509 WeakPolarHBondContact O-CA 3.07Å; G418-A509 PolarHBondContact O-N 3.48Å; W507-A509 VanDerWaalsContact C-N 3.29Å; W507-A509 PolarHBondContact O-N 2.83Å; A509-S512 PolarHBondContact O-OG 2.66Å; A509-C513 WeakPolarHBondContact O-CB 3Å; A509-C513 PolarHBondContact O-N 3.23Å
510	G	95.7	Very high	93.4	Very high	1 Å²	1	29.4 Å²	29.4	1%	0.01	15%	0.147	C	C	.	.	H	α-helix	trans	-66.7	-47.8	179.8	0	0	0	0	0	112.6	F250 W507 S512 C513 L514	F250-G510 VanDerWaalsContact CG-CA 3.46Å; W507-G510 PolarHBondContact O-N 3.18Å; W507-G510 VanDerWaalsContact O-N 3.15Å; G510-S512 PolarHBondContact O-N 3.37Å; G510-C513 PolarHBondContact O-N 3.04Å; G510-L514 WeakPolarHBondContact O-CB 3.36Å; G510-L514 VanDerWaalsContact O-CG 3.23Å; G510-L514 WeakPolarHBondContact O-CG 3.31Å; G510-L514 PolarHBondContact O-N 3.1Å
511	F	95.4	Very high	94	Very high	57 Å²	57	27 Å²	27	25%	0.25	14%	0.137	C	C	.	.	H	α-helix	trans	-57	-51.6	178.5	171.8	-105.7	0	0	0	112	V456 F500 L503 W507 L514 I515	V456-F511 HydrophobicContact CG2-CD1 4.35Å; V456-F511 HydrophobicContact CG2-CE1 3.64Å; V456-F511 HydrophobicContact CG2-CZ 4.09Å; F500-F511 HydrophobicContact CE2-CE2 4.32Å; F500-F511 HydrophobicContact CE2-CZ 4.16Å; F500-F511 HydrophobicContact CZ-CE2 4.46Å; F500-F511 AromaticContact CZ-CZ 3.86Å; F500-F511 HydrophobicContact CZ-CZ 3.86Å; L503-F511 HydrophobicContact CD2-CB 4.4Å; L503-F511 HydrophobicContact CD2-CG 4.41Å; W507-F511 VanDerWaalsContact O-CB 3.27Å; W507-F511 WeakPolarHBondContact O-CB 3.43Å; W507-F511 PolarHBondContact O-N 3.4Å; F511-L514 PolarHBondContact O-N 2.91Å; F511-I515 HydrophobicContact CD1-CD1 3.94Å; F511-I515 HydrophobicContact CD2-CD1 4.38Å; F511-I515 HydrophobicContact CE1-CD1 3.38Å; F511-I515 HydrophobicContact CE2-CD1 3.88Å; F511-I515 HydrophobicContact CG-CD1 4.42Å; F511-I515 HydrophobicContact CZ-CD1 3.36Å; F511-I515 HydrophobicContact CZ-CG1 4.43Å; F511-I515 WeakPolarHBondContact O-CG1 3.44Å; F511-I515 PolarHBondContact O-N 3.32Å
512	S	96.4	Very high	94.6	Very high	0 Å²	0	29.2 Å²	29.2	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-69.8	-38.4	-178.8	59	0	0	0	0	112.6	G418 G422 P423 Y508 A509 G510 L514 I515 V516	G418-S512 PolarHBondContact O-OG 3.04Å; G422-S512 WeakPolarHBondContact CA-OG 3.38Å; P423-S512 VanDerWaalsContact CD-OG 3.28Å; P423-S512 WeakPolarHBondContact CD-OG 3.24Å; Y508-S512 WeakPolarHBondContact O-CB 3.49Å; Y508-S512 PolarHBondContact O-N 3.31Å; Y508-S512 PolarHBondContact O-OG 3.12Å; A509-S512 PolarHBondContact O-OG 2.66Å; G510-S512 PolarHBondContact O-N 3.37Å; S512-L514 VanDerWaalsContact C-N 3.33Å; S512-L514 PolarHBondContact O-N 3.25Å; S512-I515 PolarHBondContact O-N 2.87Å; S512-V516 WeakPolarHBondContact O-CG2 3.3Å; S512-V516 PolarHBondContact O-N 2.89Å
513	C	97.6	Very high	95.3	Very high	1 Å²	1	29.1 Å²	29.1	1%	0.007	15%	0.152	C	C	.	.	H	α-helix	trans	-56.8	-45.8	171.8	176.1	0	0	0	0	111.6	F250 G422 G426 A509 G510 V516 I517	F250-C513 HydrophobicContact CD1-CB 4.27Å; G422-C513 WeakPolarHBondContact O-CA 3.27Å; G426-C513 WeakPolarHBondContact CA-SG 3.16Å; A509-C513 WeakPolarHBondContact O-CB 3Å; A509-C513 PolarHBondContact O-N 3.23Å; G510-C513 PolarHBondContact O-N 3.04Å; C513-V516 PolarHBondContact O-N 3.35Å; C513-I517 WeakPolarHBondContact O-CG1 3.27Å; C513-I517 PolarHBondContact O-N 3.34Å; C513-I517 VanDerWaalsContact O-N 3.08Å
514	L	97.1	Very high	95.8	Very high	90 Å²	90	27.9 Å²	27.9	47%	0.471	15%	0.146	S	C	.	.	H	α-helix	trans	-63.5	-41	177.2	-72.6	170.6	0	0	0	112.1	G510 F511 S512 V516 I517 L518	G510-L514 WeakPolarHBondContact O-CB 3.36Å; G510-L514 VanDerWaalsContact O-CG 3.23Å; G510-L514 WeakPolarHBondContact O-CG 3.31Å; G510-L514 PolarHBondContact O-N 3.1Å; F511-L514 PolarHBondContact O-N 2.91Å; S512-L514 VanDerWaalsContact C-N 3.33Å; S512-L514 PolarHBondContact O-N 3.25Å; L514-V516 VanDerWaalsContact C-N 3.34Å; L514-V516 PolarHBondContact O-N 3.36Å; L514-I517 PolarHBondContact O-N 2.88Å; L514-L518 WeakPolarHBondContact O-CB 3.21Å; L514-L518 VanDerWaalsContact O-CG 3.28Å; L514-L518 WeakPolarHBondContact O-CG 3.45Å; L514-L518 PolarHBondContact O-N 3.44Å
515	I	98	Very high	96	Very high	33 Å²	33	33 Å²	33	17%	0.169	17%	0.168	C	C	.	.	H	α-helix	trans	-59.1	-46.9	174.6	-70.2	168.2	0	0	0	110.8	A448 F511 S512 I517 L518 V519	A448-I515 HydrophobicContact CB-CG2 3.91Å; F511-I515 HydrophobicContact CD1-CD1 3.94Å; F511-I515 HydrophobicContact CD2-CD1 4.38Å; F511-I515 HydrophobicContact CE1-CD1 3.38Å; F511-I515 HydrophobicContact CE2-CD1 3.88Å; F511-I515 HydrophobicContact CG-CD1 4.42Å; F511-I515 HydrophobicContact CZ-CD1 3.36Å; F511-I515 HydrophobicContact CZ-CG1 4.43Å; F511-I515 WeakPolarHBondContact O-CG1 3.44Å; F511-I515 PolarHBondContact O-N 3.32Å; S512-I515 PolarHBondContact O-N 2.87Å; I515-I517 VanDerWaalsContact C-N 3.28Å; I515-I517 PolarHBondContact O-N 3.09Å; I515-L518 PolarHBondContact O-N 3.48Å; I515-V519 HydrophobicContact CG2-CG2 4.03Å; I515-V519 WeakPolarHBondContact O-CB 3.25Å; I515-V519 WeakPolarHBondContact O-CG2 3.33Å; I515-V519 PolarHBondContact O-N 2.83Å
516	V	98.5	Very high	96.3	Very high	0 Å²	0	39 Å²	39	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-57.6	-44.8	178.6	175.8	0	0	0	0	110.9	P423 L427 G445 S512 C513 L514 G520	P423-V516 HydrophobicContact CB-CG2 3.99Å; L427-V516 HydrophobicContact CB-CG1 4.41Å; G445-V516 WeakPolarHBondContact O-CG2 3Å; S512-V516 WeakPolarHBondContact O-CG2 3.3Å; S512-V516 PolarHBondContact O-N 2.89Å; C513-V516 PolarHBondContact O-N 3.35Å; L514-V516 VanDerWaalsContact C-N 3.34Å; L514-V516 PolarHBondContact O-N 3.36Å; V516-G520 VanDerWaalsContact O-CA 3.3Å; V516-G520 WeakPolarHBondContact O-CA 3.32Å; V516-G520 PolarHBondContact O-N 2.92Å
517	I	97.9	Very high	96.4	Very high	23 Å²	23	41.8 Å²	41.8	12%	0.118	22%	0.218	C	C	.	.	H	α-helix	trans	-66.6	-50.5	179.9	-66.5	168.3	0	0	0	110.7	C429 F434 C513 L514 I515 G520 L521	C429-I517 HydrophobicContact CB-CD1 4.02Å; F434-I517 HydrophobicContact CE2-CD1 4.43Å; F434-I517 HydrophobicContact CE2-CG2 3.79Å; F434-I517 HydrophobicContact CZ-CG2 3.78Å; C513-I517 WeakPolarHBondContact O-CG1 3.27Å; C513-I517 PolarHBondContact O-N 3.34Å; C513-I517 VanDerWaalsContact O-N 3.08Å; L514-I517 PolarHBondContact O-N 2.88Å; I515-I517 VanDerWaalsContact C-N 3.28Å; I515-I517 PolarHBondContact O-N 3.09Å; I517-G520 PolarHBondContact O-N 3.46Å; I517-L521 HydrophobicContact CG2-CD1 3.78Å; I517-L521 HydrophobicContact CG2-CG 4.32Å; I517-L521 VanDerWaalsContact O-CB 3.27Å; I517-L521 WeakPolarHBondContact O-CB 3.43Å; I517-L521 WeakPolarHBondContact O-CG 3.26Å; I517-L521 PolarHBondContact O-N 3.21Å
518	L	97.9	Very high	96.2	Very high	112 Å²	112	41.2 Å²	41.2	59%	0.586	23%	0.227	S	C	*	.	H	α-helix	trans	-64.4	-50.1	-175.8	-70	174.4	0	0	0	112.1	L514 I515 T522	L514-L518 WeakPolarHBondContact O-CB 3.21Å; L514-L518 VanDerWaalsContact O-CG 3.28Å; L514-L518 WeakPolarHBondContact O-CG 3.45Å; L514-L518 PolarHBondContact O-N 3.44Å; I515-L518 PolarHBondContact O-N 3.48Å; L518-T522 WeakPolarHBondContact O-CB 3.41Å; L518-T522 PolarHBondContact O-N 3.44Å; L518-T522 PolarHBondContact O-OG1 2.92Å
519	V	98.3	Very high	95.7	Very high	47 Å²	47	44.1 Å²	44.1	29%	0.285	25%	0.247	S	C	.	.	H	α-helix	trans	-67	-42.3	178.1	175.5	0	0	0	0	110.1	A448 I515 L521 T522 V523	A448-V519 HydrophobicContact CB-CB 4.13Å; A448-V519 HydrophobicContact CB-CG1 3.88Å; A448-V519 HydrophobicContact CB-CG2 3.91Å; I515-V519 HydrophobicContact CG2-CG2 4.03Å; I515-V519 WeakPolarHBondContact O-CB 3.25Å; I515-V519 WeakPolarHBondContact O-CG2 3.33Å; I515-V519 PolarHBondContact O-N 2.83Å; V519-L521 PolarHBondContact O-N 3.13Å; V519-T522 PolarHBondContact O-N 3.47Å; V519-V523 HydrophobicContact CG1-CG2 4.16Å; V519-V523 WeakPolarHBondContact O-CB 3.38Å; V519-V523 WeakPolarHBondContact O-CG2 3.36Å; V519-V523 PolarHBondContact O-N 3.43Å
520	G	97.7	Very high	95.2	Very high	0 Å²	0	45.3 Å²	45.3	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-63.9	-40	-179.3	0	0	0	0	0	113.1	G441 V516 I517 S524	G441-G520 WeakPolarHBondContact CA-O 3.35Å; G441-G520 WeakPolarHBondContact O-CA 3.34Å; V516-G520 VanDerWaalsContact O-CA 3.3Å; V516-G520 WeakPolarHBondContact O-CA 3.32Å; V516-G520 PolarHBondContact O-N 2.92Å; I517-G520 PolarHBondContact O-N 3.46Å; G520-S524 VanDerWaalsContact O-CB 3.24Å; G520-S524 WeakPolarHBondContact O-CB 3.21Å; G520-S524 PolarHBondContact O-N 3.4Å; G520-S524 PolarHBondContact O-OG 3.43Å
521	L	96.6	Very high	94.4	Very high	25 Å²	25	52.2 Å²	52.2	13%	0.131	28%	0.282	C	S	.	.	H	α-helix	trans	-66.5	-47.8	172.7	-72.9	177.5	0	0	0	111.8	L430 F434 W436 I517 V519 V523 S524 F525	L430-L521 HydrophobicContact CD1-CD2 3.83Å; L430-L521 HydrophobicContact CD1-CG 3.86Å; F434-L521 HydrophobicContact CB-CD2 3.87Å; F434-L521 HydrophobicContact CD1-CD1 3.82Å; F434-L521 HydrophobicContact CD1-CD2 3.86Å; F434-L521 HydrophobicContact CD1-CG 4.39Å; F434-L521 HydrophobicContact CE1-CD1 3.76Å; F434-L521 HydrophobicContact CG-CD1 4.39Å; F434-L521 HydrophobicContact CG-CD2 3.92Å; F434-L521 HydrophobicContact CZ-CD1 4.28Å; W436-L521 VanDerWaalsContact CD1-CD2 3.43Å; I517-L521 HydrophobicContact CG2-CD1 3.78Å; I517-L521 HydrophobicContact CG2-CG 4.32Å; I517-L521 VanDerWaalsContact O-CB 3.27Å; I517-L521 WeakPolarHBondContact O-CB 3.43Å; I517-L521 WeakPolarHBondContact O-CG 3.26Å; I517-L521 PolarHBondContact O-N 3.21Å; V519-L521 PolarHBondContact O-N 3.13Å; L521-V523 PolarHBondContact O-N 2.96Å; L521-S524 WeakPolarHBondContact O-CB 3.34Å; L521-S524 PolarHBondContact O-N 3.32Å; L521-S524 VanDerWaalsContact O-N 3.13Å; L521-F525 HydrophobicContact CB-CE2 4.26Å; L521-F525 WeakPolarHBondContact O-CD2 3.21Å; L521-F525 PolarHBondContact O-N 2.61Å
522	T	97.1	Very high	93	Very high	80 Å²	80	55.1 Å²	55.1	49%	0.491	30%	0.297	S	S	.	.	H	α-helix	trans	-58	-51.2	-179.4	-56.7	0	0	0	0	111	L518 V519 S524 F525 L526	L518-T522 WeakPolarHBondContact O-CB 3.41Å; L518-T522 PolarHBondContact O-N 3.44Å; L518-T522 PolarHBondContact O-OG1 2.92Å; V519-T522 PolarHBondContact O-N 3.47Å; T522-S524 VanDerWaalsContact C-N 3.31Å; T522-S524 PolarHBondContact O-N 3.25Å; T522-F525 PolarHBondContact O-N 2.96Å; T522-L526 HydrophobicContact CG2-CD1 4.07Å; T522-L526 VanDerWaalsContact O-CG 3.3Å; T522-L526 WeakPolarHBondContact O-CG 3.42Å; T522-L526 PolarHBondContact O-N 3.45Å
523	V	97.3	Very high	91.4	Very high	35 Å²	35	59.1 Å²	59.1	21%	0.212	34%	0.337	C	S	.	.	H	α-helix	trans	-64.4	-37.3	177.4	173.8	0	0	0	0	111	A444 V519 L521 F525 L526 T527	A444-V523 HydrophobicContact CB-CB 4.24Å; A444-V523 HydrophobicContact CB-CG1 4.02Å; A444-V523 HydrophobicContact CB-CG2 3.94Å; V519-V523 HydrophobicContact CG1-CG2 4.16Å; V519-V523 WeakPolarHBondContact O-CB 3.38Å; V519-V523 WeakPolarHBondContact O-CG2 3.36Å; V519-V523 PolarHBondContact O-N 3.43Å; L521-V523 PolarHBondContact O-N 2.96Å; V523-F525 VanDerWaalsContact C-N 3.32Å; V523-F525 PolarHBondContact O-N 3.19Å; V523-L526 PolarHBondContact O-N 3.24Å; V523-T527 HydrophobicContact CG1-CG2 3.97Å; V523-T527 WeakPolarHBondContact O-CG2 3.46Å; V523-T527 PolarHBondContact O-N 3.39Å; V523-T527 PolarHBondContact O-OG1 3.15Å; V523-T527 VanDerWaalsContact O-OG1 3.11Å
524	S	95.7	Very high	90.2	Very high	0 Å²	0	65 Å²	65	0%	0	37%	0.365	C	S	.	.	H	α-helix	trans	-60.7	-41.8	176	-63	0	0	0	0	112.3	A437 N438 G520 L521 T522 G528	A437-S524 WeakPolarHBondContact CA-OG 3.49Å; N438-S524 PolarHBondContact N-OG 3.24Å; N438-S524 WeakPolarHBondContact ND2-CA 3.38Å; N438-S524 PolarHBondContact ND2-O 3.19Å; G520-S524 VanDerWaalsContact O-CB 3.24Å; G520-S524 WeakPolarHBondContact O-CB 3.21Å; G520-S524 PolarHBondContact O-N 3.4Å; G520-S524 PolarHBondContact O-OG 3.43Å; L521-S524 WeakPolarHBondContact O-CB 3.34Å; L521-S524 PolarHBondContact O-N 3.32Å; L521-S524 VanDerWaalsContact O-N 3.13Å; T522-S524 VanDerWaalsContact C-N 3.31Å; T522-S524 PolarHBondContact O-N 3.25Å; S524-G528 CarbonylContact O-C 3.04Å; S524-G528 PolarHBondContact O-N 3.31Å
525	F	94.5	Very high	89.2	Confident	112 Å²	112	61.7 Å²	61.7	49%	0.491	35%	0.35	S	S	.	.	H	α-helix	trans	-68.8	-39.6	176.3	-70.6	-58	0	0	0	112.2	W436 L521 T522 V523 P529	W436-F525 HydrophobicContact CB-CE1 4.33Å; W436-F525 AromaticContact CD1-CZ 3.49Å; W436-F525 VanDerWaalsContact CD1-CZ 3.49Å; W436-F525 HydrophobicContact CG-CE1 4.2Å; W436-F525 AromaticContact CG-CZ 3.98Å; W436-F525 HydrophobicContact CG-CZ 3.98Å; W436-F525 AromaticContact NE1-CZ 3.78Å; L521-F525 HydrophobicContact CB-CE2 4.26Å; L521-F525 WeakPolarHBondContact O-CD2 3.21Å; L521-F525 PolarHBondContact O-N 2.61Å; T522-F525 PolarHBondContact O-N 2.96Å; V523-F525 VanDerWaalsContact C-N 3.32Å; V523-F525 PolarHBondContact O-N 3.19Å; F525-P529 HydrophobicContact CD1-CB 4.19Å; F525-P529 HydrophobicContact CE1-CB 4.41Å
526	L	95.4	Very high	88.3	Confident	142 Å²	142	62.7 Å²	62.7	74%	0.743	36%	0.358	S	S	*	.	H	α-helix	trans	-68.9	-35.9	179	-69	175.1	0	0	0	113.2	T522 V523	T522-L526 HydrophobicContact CG2-CD1 4.07Å; T522-L526 VanDerWaalsContact O-CG 3.3Å; T522-L526 WeakPolarHBondContact O-CG 3.42Å; T522-L526 PolarHBondContact O-N 3.45Å; V523-L526 PolarHBondContact O-N 3.24Å
527	T	93.3	Very high	87.3	Confident	62 Å²	62	66.3 Å²	66.3	38%	0.38	38%	0.382	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94.4	6.9	-178.4	71.9	0	0	0	0	113.7	N438 K440 V523	N438-T527 PolarHBondContact ND2-OG1 3.43Å; K440-T527 HydrophobicContact CB-CG2 4.43Å; K440-T527 HydrophobicContact CD-CG2 4.04Å; V523-T527 HydrophobicContact CG1-CG2 3.97Å; V523-T527 WeakPolarHBondContact O-CG2 3.46Å; V523-T527 PolarHBondContact O-N 3.39Å; V523-T527 PolarHBondContact O-OG1 3.15Å; V523-T527 VanDerWaalsContact O-OG1 3.11Å
528	G	89.1	Confident	86.4	Confident	38 Å²	38	66.1 Å²	66.1	39%	0.392	39%	0.385	S	S	.	.			trans	96.4	113.2	-175.9	0	0	0	0	0	112.4	N438 S524	N438-G528 PolarHBondContact ND2-O 3.4Å; S524-G528 CarbonylContact O-C 3.04Å; S524-G528 PolarHBondContact O-N 3.31Å
529	P	85.8	Confident	85.7	Confident	67 Å²	67	60.8 Å²	60.8	44%	0.435	36%	0.357	S	S	.	.	P	Polyproline II helix	trans	-63.8	149.5	-178.7	27	-34.3	0	0	0	111.2	W436 F525 K531	W436-P529 HydrophobicContact CB-CB 4.15Å; F525-P529 HydrophobicContact CD1-CB 4.19Å; F525-P529 HydrophobicContact CE1-CB 4.41Å; P529-K531 PolarHBondContact O-N 2.95Å
530	M	84.4	Confident	85.1	Confident	27 Å²	27	59.5 Å²	59.5	13%	0.133	35%	0.35	C	S	.	.	P	Polyproline II helix	trans	-66.2	133.3	179	-174.7	174.3	-80.9	0	0	110.5	R121 W436 A437 N438 E534 A535	R121-M530 PolarHBondContact NH1-SD 3.1Å; W436-M530 PolarHBondContact O-N 3.44Å; A437-M530 WeakPolarHBondContact O-CB 3.28Å; N438-M530 HydrophobicContact CB-CB 4.15Å; M530-E534 HydrophobicContact CG-CB 4.13Å; M530-A535 HydrophobicContact SD-CB 4.29Å
531	K	78.5	Confident	84.4	Confident	146 Å²	146	61 Å²	61	64%	0.635	36%	0.356	S	S	*	.	P	Polyproline II helix	trans	-79.2	144.7	175.6	-64.2	177.6	-177.7	173.5	0	110	P529 G533 E534	P529-K531 PolarHBondContact O-N 2.95Å; K531-G533 VanDerWaalsContact C-N 3.25Å; K531-G533 PolarHBondContact O-N 3.32Å; K531-E534 HydrophobicContact CB-CG 4.35Å; K531-E534 WeakPolarHBondContact O-CB 3.23Å; K531-E534 PolarHBondContact O-N 3.44Å
532	E	65.9	Low	83.1	Confident	118 Å²	118	62.1 Å²	62.1	55%	0.551	36%	0.364	S	S	*	.	G	3₁₀ helix	trans	-56.8	-36	-176.7	-67.1	-176.5	175.9	0	0	113.7	E534 A535 C561	E532-E534 PolarHBondContact O-N 2.86Å; E532-A535 PolarHBondContact O-N 3.47Å; E532-C561 WeakPolarHBondContact OE1-CB 3.33Å; E532-C561 WeakPolarHBondContact OE2-CB 3.21Å
533	G	63.3	Low	81.5	Confident	83 Å²	83	61.1 Å²	61.1	86%	0.856	36%	0.355	S	S	*	.	G	3₁₀ helix	trans	-68.4	-15.2	177.9	0	0	0	0	0	114.8	K531	K531-G533 VanDerWaalsContact C-N 3.25Å; K531-G533 PolarHBondContact O-N 3.32Å
534	E	71.9	Confident	79.5	Confident	125 Å²	125	63.1 Å²	63.1	58%	0.584	37%	0.365	S	S	*	.	G	3₁₀ helix	trans	-90.9	-16.8	177.1	-63.7	171.5	-166.1	0	0	112.1	M530 K531 E532	M530-E534 HydrophobicContact CG-CB 4.13Å; K531-E534 HydrophobicContact CB-CG 4.35Å; K531-E534 WeakPolarHBondContact O-CB 3.23Å; K531-E534 PolarHBondContact O-N 3.44Å; E532-E534 PolarHBondContact O-N 2.86Å
535	A	75.8	Confident	77.4	Confident	20 Å²	20	64.4 Å²	64.4	17%	0.165	38%	0.377	C	S	.	.	S	Bend	trans	-80.3	125.9	179.2	0	0	0	0	0	110.9	M530 E532 P537	M530-A535 HydrophobicContact SD-CB 4.29Å; E532-A535 PolarHBondContact O-N 3.47Å; A535-P537 WeakPolarHBondContact O-CD 3.44Å
536	T	79.4	Confident	75.7	Confident	55 Å²	55	65.2 Å²	65.2	34%	0.337	38%	0.381	S	S	.	.	P	Polyproline II helix	trans	-60.9	125.3	177	-57	0	0	0	0	110.6	L120 G538 T539	L120-T536 VanDerWaalsContact O-CB 3.28Å; L120-T536 WeakPolarHBondContact O-CB 3.49Å; L120-T536 PolarHBondContact O-OG1 3.31Å; T536-G538 PolarHBondContact O-N 3.41Å; T536-T539 HydrophobicContact CG2-CG2 4.15Å; T536-T539 WeakPolarHBondContact O-CB 3.36Å; T536-T539 WeakPolarHBondContact O-CG2 3.33Å; T536-T539 PolarHBondContact O-N 2.82Å; T536-T539 PolarHBondContact O-OG1 3.37Å
537	P	77.8	Confident	73.7	Confident	76 Å²	76	64.8 Å²	64.8	49%	0.494	38%	0.378	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55.1	137.4	-179.6	-27.2	34.6	0	0	0	112.7	A535 T539	A535-P537 WeakPolarHBondContact O-CD 3.44Å; P537-T539 VanDerWaalsContact C-N 3.34Å
538	G	78.9	Confident	71.7	Confident	18 Å²	18	64.2 Å²	64.2	19%	0.186	37%	0.373	C	S	.	.	T	Hydrogen-bonded Turn	trans	84.4	-1.1	179.3	0	0	0	0	0	116.1	T536 L565	T536-G538 PolarHBondContact O-N 3.41Å; G538-L565 VanDerWaalsContact CA-CD1 3.5Å
539	T	84.1	Confident	70.1	Confident	0 Å²	0	69 Å²	69	0%	0	38%	0.383	C	S	.	.	S	Bend	trans	-88	-13.6	176	61.7	0	0	0	0	114	Y117 L120 T536 P537	Y117-T539 HydrophobicContact CD2-CG2 4.48Å; Y117-T539 HydrophobicContact CE2-CG2 4.27Å; Y117-T539 VanDerWaalsContact CE2-O 3.24Å; Y117-T539 WeakPolarHBondContact CE2-O 3Å; Y117-T539 PolarHBondContact OH-O 3.09Å; L120-T539 HydrophobicContact CB-CG2 4.05Å; T536-T539 HydrophobicContact CG2-CG2 4.15Å; T536-T539 WeakPolarHBondContact O-CB 3.36Å; T536-T539 WeakPolarHBondContact O-CG2 3.33Å; T536-T539 PolarHBondContact O-N 2.82Å; T536-T539 PolarHBondContact O-OG1 3.37Å; P537-T539 VanDerWaalsContact C-N 3.34Å
540	V	85.8	Confident	68.6	Low	21 Å²	21	74.3 Å²	74.3	13%	0.127	40%	0.4	C	S	.	.	S	Bend	trans	-106.9	129.6	178.5	-179.1	0	0	0	0	109.4	P435 V562	P435-V540 HydrophobicContact CB-CG1 4.34Å; V540-V562 HydrophobicContact CG1-CG2 4.49Å
541	Y	81.6	Confident	67	Low	32 Å²	32	75.8 Å²	75.8	13%	0.125	41%	0.408	C	S	.	.			trans	-87	124.8	172.6	-167.4	-89.5	0	0	0	109.6	H100 V101 M432 F433 L543 K546	H100-Y541 WeakPolarHBondContact O-CE2 3.21Å; H100-Y541 PolarHBondContact O-OH 3.39Å; V101-Y541 HydrophobicContact CB-CE2 4.34Å; V101-Y541 HydrophobicContact CG1-CD1 4.12Å; V101-Y541 HydrophobicContact CG1-CD2 3.93Å; V101-Y541 HydrophobicContact CG1-CE1 4.4Å; V101-Y541 HydrophobicContact CG1-CE2 4.19Å; V101-Y541 HydrophobicContact CG1-CG 3.89Å; V101-Y541 HydrophobicContact CG2-CE1 4.14Å; V101-Y541 HydrophobicContact CG2-CE2 4.37Å; M432-Y541 PolarHBondContact O-N 3.26Å; F433-Y541 HydrophobicContact CE1-CD1 4.36Å; Y541-L543 HydrophobicContact CD1-CB 4.06Å; Y541-L543 HydrophobicContact CD1-CD1 3.96Å; Y541-L543 HydrophobicContact CE1-CD1 3.98Å; Y541-L543 PolarHBondContact O-N 3.28Å; Y541-K546 HydrophobicContact CE1-CD 4.43Å; Y541-K546 PolarHBondContact OH-NZ 3.15Å
542	P	69.1	Low	66	Low	47 Å²	47	73 Å²	73	31%	0.305	41%	0.405	S	S	.	.			trans	-76.4	62.3	-178.5	32.2	-35.8	0	0	0	111.7	G545 K546 V562	P542-G545 PolarHBondContact O-N 3.17Å; P542-K546 PolarHBondContact O-N 2.75Å; P542-V562 HydrophobicContact CB-CB 4.05Å; P542-V562 HydrophobicContact CB-CG1 4.14Å; P542-V562 HydrophobicContact CB-CG2 3.87Å
543	L	64.9	Low	65.4	Low	59 Å²	59	76.3 Å²	76.3	31%	0.309	42%	0.417	S	S	.	.	H	α-helix	trans	-62.3	-48.7	-177.8	-161.6	90.1	0	0	0	110.5	F433 Y541 G545 K546 L547	F433-L543 HydrophobicContact CD1-CB 3.96Å; F433-L543 HydrophobicContact CD1-CD1 4.23Å; F433-L543 HydrophobicContact CD1-CD2 4.27Å; F433-L543 HydrophobicContact CD1-CG 4.38Å; F433-L543 HydrophobicContact CE1-CB 4.4Å; F433-L543 HydrophobicContact CE1-CD1 3.86Å; F433-L543 HydrophobicContact CE1-CG 4.49Å; Y541-L543 HydrophobicContact CD1-CB 4.06Å; Y541-L543 HydrophobicContact CD1-CD1 3.96Å; Y541-L543 HydrophobicContact CE1-CD1 3.98Å; Y541-L543 PolarHBondContact O-N 3.28Å; L543-G545 VanDerWaalsContact C-N 3.29Å; L543-G545 PolarHBondContact O-N 3.34Å; L543-K546 PolarHBondContact O-N 3.44Å; L543-L547 HydrophobicContact CG-CD1 4.21Å; L543-L547 WeakPolarHBondContact O-CB 3.24Å; L543-L547 PolarHBondContact O-N 3.11Å
544	L	54.2	Low	64.9	Low	78 Å²	78	79.5 Å²	79.5	41%	0.408	41%	0.41	S	S	.	.	H	α-helix	trans	-61.3	-36.9	176.6	-106.8	71.8	0	0	0	112	K546 L548 V559 C560	L544-K546 VanDerWaalsContact C-N 3.31Å; L544-K546 PolarHBondContact O-N 3.32Å; L544-L548 HydrophobicContact CB-CD1 4.01Å; L544-L548 HydrophobicContact CD2-CD1 3.96Å; L544-L548 HydrophobicContact CG-CD1 3.78Å; L544-L548 HydrophobicContact CG-CG 4.49Å; L544-L548 WeakPolarHBondContact O-CA 3.42Å; L544-L548 WeakPolarHBondContact O-CB 3.33Å; L544-L548 VanDerWaalsContact O-CG 3.24Å; L544-L548 WeakPolarHBondContact O-CG 3.21Å; L544-L548 PolarHBondContact O-N 2.83Å; L544-V559 HydrophobicContact CD2-CG1 3.54Å; L544-C560 VanDerWaalsContact C-SG 3.53Å
545	G	52	Low	63.8	Low	26 Å²	26	78.4 Å²	78.4	27%	0.268	41%	0.406	S	S	.	.	H	α-helix	trans	-66.2	-32.1	179.2	0	0	0	0	0	113.6	P542 L543 C560	P542-G545 PolarHBondContact O-N 3.17Å; L543-G545 VanDerWaalsContact C-N 3.29Å; L543-G545 PolarHBondContact O-N 3.34Å; G545-C560 WeakPolarHBondContact CA-SG 3.38Å; G545-C560 PolarHBondContact N-SG 3.5Å
546	K	58.3	Low	62.5	Low	130 Å²	130	79.9 Å²	79.9	57%	0.565	41%	0.408	S	S	*	.	H	α-helix	trans	-84.9	-41.4	175.5	-73.4	-173.9	-179.4	180	0	113	Y541 P542 L543 L544 F549	Y541-K546 HydrophobicContact CE1-CD 4.43Å; Y541-K546 PolarHBondContact OH-NZ 3.15Å; P542-K546 PolarHBondContact O-N 2.75Å; L543-K546 PolarHBondContact O-N 3.44Å; L544-K546 VanDerWaalsContact C-N 3.31Å; L544-K546 PolarHBondContact O-N 3.32Å; K546-F549 WeakPolarHBondContact O-CB 3.29Å; K546-F549 PolarHBondContact O-N 2.92Å
547	L	54.4	Low	61	Low	132 Å²	132	84.8 Å²	84.8	69%	0.691	43%	0.425	S	S	*	.	H	α-helix	trans	-71	-37	179.2	-114.4	98.2	0	0	0	112.3	L543 F549	L543-L547 HydrophobicContact CG-CD1 4.21Å; L543-L547 WeakPolarHBondContact O-CB 3.24Å; L543-L547 PolarHBondContact O-N 3.11Å; L547-F549 PolarHBondContact O-N 3.08Å
548	L	50.5	Low	59.5	Low	50 Å²	50	87.2 Å²	87.2	26%	0.262	43%	0.434	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.6	30.2	176.5	-57.1	166.5	0	0	0	111.6	L544 F550 L551 K556 V559	L544-L548 HydrophobicContact CB-CD1 4.01Å; L544-L548 HydrophobicContact CD2-CD1 3.96Å; L544-L548 HydrophobicContact CG-CD1 3.78Å; L544-L548 HydrophobicContact CG-CG 4.49Å; L544-L548 WeakPolarHBondContact O-CA 3.42Å; L544-L548 WeakPolarHBondContact O-CB 3.33Å; L544-L548 VanDerWaalsContact O-CG 3.24Å; L544-L548 WeakPolarHBondContact O-CG 3.21Å; L544-L548 PolarHBondContact O-N 2.83Å; L548-F550 PolarHBondContact O-N 2.92Å; L548-L551 HydrophobicContact CB-CB 4.29Å; L548-L551 HydrophobicContact CB-CD1 4.37Å; L548-L551 HydrophobicContact CD2-CD1 3.85Å; L548-L551 PolarHBondContact O-N 2.81Å; L548-K556 WeakPolarHBondContact O-CE 3.2Å; L548-V559 HydrophobicContact CD1-CG1 3.82Å
549	F	54.8	Low	57.9	Low	140 Å²	140	89.2 Å²	89.2	61%	0.614	44%	0.442	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.3	-31.8	175.3	155.7	-100.4	0	0	0	112	K546 L547 L551 K556	K546-F549 WeakPolarHBondContact O-CB 3.29Å; K546-F549 PolarHBondContact O-N 2.92Å; L547-F549 PolarHBondContact O-N 3.08Å; F549-L551 PolarHBondContact O-N 3.05Å; F549-K556 PolarHBondContact O-NZ 3.47Å
550	F	55.7	Low	56.1	Low	178 Å²	178	90.8 Å²	90.8	78%	0.781	45%	0.453	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.4	-12.2	178.1	-61.5	-79	0	0	0	115.3	L548	L548-F550 PolarHBondContact O-N 2.92Å
551	L	49.9	Very low	54.2	Low	58 Å²	58	92.5 Å²	92.5	30%	0.304	47%	0.465	S	S	.	.	S	Bend	trans	-79.3	144	179	-106.2	77.7	0	0	0	112.8	L548 F549 M555 K556	L548-L551 HydrophobicContact CB-CB 4.29Å; L548-L551 HydrophobicContact CB-CD1 4.37Å; L548-L551 HydrophobicContact CD2-CD1 3.85Å; L548-L551 PolarHBondContact O-N 2.81Å; F549-L551 PolarHBondContact O-N 3.05Å; L551-M555 HydrophobicContact CD2-CB 3.84Å; L551-M555 HydrophobicContact CD2-SD 4.46Å; L551-K556 HydrophobicContact CB-CG 4.39Å; L551-K556 WeakPolarHBondContact O-CE 3.38Å; L551-K556 PolarHBondContact O-NZ 3.43Å
552	P	56.9	Low	52.6	Low	87 Å²	87	93.6 Å²	93.6	57%	0.565	48%	0.475	S	S	*	.			trans	-56.7	145.2	175.1	-22.2	31.8	0	0	0	112.9	H554 M555 K556	P552-H554 PolarHBondContact O-N 3Å; P552-M555 PolarHBondContact O-N 3.5Å; P552-K556 PolarHBondContact O-N 2.81Å; P552-K556 VanDerWaalsContact O-N 3.13Å
553	K	54.8	Low	51.3	Low	187 Å²	187	95.7 Å²	95.7	81%	0.813	49%	0.487	S	S	*	.	H	α-helix	trans	-54.1	-30.1	-176.6	-69.1	-177.9	-179.5	176.6	0	113.9	K557	K553-K557 PolarHBondContact O-N 2.77Å
554	H	53.1	Low	50.1	Low	151 Å²	151	97.8 Å²	97.8	70%	0.699	50%	0.504	S	S	*	.	H	α-helix	trans	-70.1	-36.1	178.4	-165	-83.9	0	0	0	112.9	P552	P552-H554 PolarHBondContact O-N 3Å
555	M	48.7	Very low	49.3	Very low	101 Å²	101	98.5 Å²	98.5	50%	0.498	51%	0.508	S	S	.	.	H	α-helix	trans	-80.3	-31.1	175.4	-65.4	-143.9	77.6	0	0	112.3	L551 P552 K557 N558 V559	L551-M555 HydrophobicContact CD2-CB 3.84Å; L551-M555 HydrophobicContact CD2-SD 4.46Å; P552-M555 PolarHBondContact O-N 3.5Å; M555-K557 VanDerWaalsContact C-N 3.25Å; M555-K557 PolarHBondContact O-N 2.61Å; M555-N558 PolarHBondContact O-N 3.37Å; M555-V559 WeakPolarHBondContact O-CB 3.18Å; M555-V559 VanDerWaalsContact O-CG2 3.3Å; M555-V559 WeakPolarHBondContact O-CG2 3.41Å; M555-V559 PolarHBondContact O-N 3.46Å; M555-V559 VanDerWaalsContact O-N 3.16Å
556	K	48.4	Very low	48.2	Very low	51 Å²	51	108.3 Å²	108.3	22%	0.222	54%	0.537	C	S	.	.	H	α-helix	trans	-60.2	-34.2	170.2	-77.1	178.4	178.1	160.5	0	112.5	L548 F549 L551 P552 N558 V559 C560	L548-K556 WeakPolarHBondContact O-CE 3.2Å; F549-K556 PolarHBondContact O-NZ 3.47Å; L551-K556 HydrophobicContact CB-CG 4.39Å; L551-K556 WeakPolarHBondContact O-CE 3.38Å; L551-K556 PolarHBondContact O-NZ 3.43Å; P552-K556 PolarHBondContact O-N 2.81Å; P552-K556 VanDerWaalsContact O-N 3.13Å; K556-N558 VanDerWaalsContact C-N 3.27Å; K556-N558 PolarHBondContact O-N 3.03Å; K556-V559 PolarHBondContact O-N 3.2Å; K556-C560 CarbonylContact O-C 3.51Å; K556-C560 VanDerWaalsContact O-CA 3.29Å; K556-C560 WeakPolarHBondContact O-CA 3.24Å; K556-C560 VanDerWaalsContact O-CB 3.28Å; K556-C560 WeakPolarHBondContact O-CB 3.34Å; K556-C560 PolarHBondContact O-N 3.36Å
557	K	47.8	Very low	46.7	Very low	159 Å²	159	107.4 Å²	107.4	69%	0.691	54%	0.544	S	S	*	.	H	α-helix	trans	-69.4	-25.1	178.3	-142.4	-179.3	-175.9	-173.9	0	113.1	K553 M555 C561	K553-K557 PolarHBondContact O-N 2.77Å; M555-K557 VanDerWaalsContact C-N 3.25Å; M555-K557 PolarHBondContact O-N 2.61Å; K557-C561 PolarHBondContact O-SG 2.9Å
558	N	44.8	Very low	45.6	Very low	126 Å²	126	106.2 Å²	106.2	67%	0.674	55%	0.554	S	S	*	*	H	α-helix	trans	-90.4	-17.1	176.7	-70.1	-5.6	0	0	0	113.1	M555 K556	M555-N558 PolarHBondContact O-N 3.37Å; K556-N558 VanDerWaalsContact C-N 3.27Å; K556-N558 PolarHBondContact O-N 3.03Å
559	V	45.8	Very low	44.9	Very low	61 Å²	61	110.8 Å²	110.8	37%	0.37	58%	0.577	S	S	.	*	H	α-helix	trans	-117.4	-20.8	-171.9	179.8	0	0	0	0	112.8	L544 L548 M555 K556	L544-V559 HydrophobicContact CD2-CG1 3.54Å; L548-V559 HydrophobicContact CD1-CG1 3.82Å; M555-V559 WeakPolarHBondContact O-CB 3.18Å; M555-V559 VanDerWaalsContact O-CG2 3.3Å; M555-V559 WeakPolarHBondContact O-CG2 3.41Å; M555-V559 PolarHBondContact O-N 3.46Å; M555-V559 VanDerWaalsContact O-N 3.16Å; K556-V559 PolarHBondContact O-N 3.2Å
560	C	46.8	Very low	43.9	Very low	32 Å²	32	109.6 Å²	109.6	22%	0.216	58%	0.583	C	S	.	*			trans	-135.2	67	-174.1	-63.4	0	0	0	0	110.9	L544 G545 K556 V562	L544-C560 VanDerWaalsContact C-SG 3.53Å; G545-C560 WeakPolarHBondContact CA-SG 3.38Å; G545-C560 PolarHBondContact N-SG 3.5Å; K556-C560 CarbonylContact O-C 3.51Å; K556-C560 VanDerWaalsContact O-CA 3.29Å; K556-C560 WeakPolarHBondContact O-CA 3.24Å; K556-C560 VanDerWaalsContact O-CB 3.28Å; K556-C560 WeakPolarHBondContact O-CB 3.34Å; K556-C560 PolarHBondContact O-N 3.36Å; C560-V562 PolarHBondContact O-N 3.5Å
561	C	46.4	Very low	42.6	Very low	58 Å²	58	106 Å²	106	39%	0.392	58%	0.58	S	S	.	*			trans	-91.8	86.9	163.7	-79.5	0	0	0	0	108.7	E532 K557	E532-C561 WeakPolarHBondContact OE1-CB 3.33Å; E532-C561 WeakPolarHBondContact OE2-CB 3.21Å; K557-C561 PolarHBondContact O-SG 2.9Å
562	V	47.2	Very low	41.8	Very low	54 Å²	54	109.2 Å²	109.2	33%	0.327	61%	0.605	S	S	.	*			trans	-116	116.9	171.5	-179.4	0	0	0	0	108.1	V540 P542 C560 P564	V540-V562 HydrophobicContact CG1-CG2 4.49Å; P542-V562 HydrophobicContact CB-CB 4.05Å; P542-V562 HydrophobicContact CB-CG1 4.14Å; P542-V562 HydrophobicContact CB-CG2 3.87Å; C560-V562 PolarHBondContact O-N 3.5Å; V562-P564 WeakPolarHBondContact O-CD 3.38Å
563	T	42.6	Very low	40.5	Very low	91 Å²	91	113.5 Å²	113.5	56%	0.558	62%	0.617	S	S	*	*	P	Polyproline II helix	trans	-70.8	119.5	174.9	-32	0	0	0	0	109.2
564	P	39.4	Very low	39.3	Very low	104 Å²	104	107.4 Å²	107.4	68%	0.675	61%	0.607	S	S	*	*	P	Polyproline II helix	trans	-68.7	146.8	173.7	26.1	-30.1	0	0	0	110.6	V562 R566	V562-P564 WeakPolarHBondContact O-CD 3.38Å; P564-R566 PolarHBondContact O-N 3.23Å; P564-R566 VanDerWaalsContact O-N 3.14Å
565	L	36.2	Very low	38.2	Very low	93 Å²	93	106.7 Å²	106.7	49%	0.487	62%	0.616	S	S	.	*	P	Polyproline II helix	trans	-52.1	116.9	167.5	-112.3	136.5	0	0	0	108.7	G538	G538-L565 VanDerWaalsContact CA-CD1 3.5Å
566	R	29.1	Very low	37.1	Very low	231 Å²	231	112.6 Å²	112.6	87%	0.872	63%	0.633	S	S	*	*	P	Polyproline II helix	trans	-59	127.8	168.6	-91.2	-177.4	175.4	174.2	-1.3	107.9	P564 A568	P564-R566 PolarHBondContact O-N 3.23Å; P564-R566 VanDerWaalsContact O-N 3.14Å; R566-A568 PolarHBondContact O-N 3.07Å
567	P	28.3	Very low	36.2	Very low	111 Å²	111	115.6 Å²	115.6	72%	0.721	66%	0.66	S	S	*	*	P	Polyproline II helix	trans	-60.7	132.9	167.3	24	-29.3	0	0	0	108.6	I569	P567-I569 PolarHBondContact O-N 3.49Å
568	A	29.6	Very low	35.1	Very low	108 Å²	108	116.8 Å²	116.8	89%	0.893	67%	0.668	S	S	*	*	P	Polyproline II helix	trans	-64.3	124.1	173.7	0	0	0	0	0	109.9	R566	R566-A568 PolarHBondContact O-N 3.07Å
569	I	36.8	Very low	34.3	Very low	145 Å²	145	120.5 Å²	120.5	74%	0.744	68%	0.678	S	S	*	*			trans	-136.2	133.4	165.5	-64.9	-177.2	0	0	0	104.2	P567	P567-I569 PolarHBondContact O-N 3.49Å
570	P	32.7	Very low	33.3	Very low	116 Å²	116	126.5 Å²	126.5	75%	0.753	70%	0.702	S	S	*	*				-134.6	144	54.1	27.3	-4.5	0	0	0	117.2
571	S	29	Very low	32.3	Very low	102 Å²	102	130.7 Å²	130.7	71%	0.713	73%	0.731	S	S	*	*	P	Polyproline II helix	trans	-71.2	137.4	155.2	41.1	0	0	0	0	109.1	Q573	S571-Q573 PolarHBondContact O-N 3.35Å
572	P	33	Very low	31.4	Very low	126 Å²	126	135.9 Å²	135.9	82%	0.818	76%	0.755	S	S	*	*	P	Polyproline II helix	trans	-66.2	130.1	174.8	-10.6	24.6	0	0	0	109.4	G574	P572-G574 PolarHBondContact O-N 2.87Å
573	Q	30.5	Very low	30.5	Very low	177 Å²	177	136.8 Å²	136.8	83%	0.827	78%	0.776	S	S	*	*	P	Polyproline II helix	trans	-59.4	127.6	162.8	-74.1	179.8	-15.6	0	0	108.3	S571	S571-Q573 PolarHBondContact O-N 3.35Å
574	G	29.5	Very low	29.6	Very low	58 Å²	58	139.4 Å²	139.4	60%	0.598	79%	0.792	S	S	*	*	P	Polyproline II helix	trans	-60	166.8	173.8	0	0	0	0	0	112.7	P572 R576	P572-G574 PolarHBondContact O-N 2.87Å; G574-R576 PolarHBondContact O-N 3.44Å
575	P	29.7	Very low	29.1	Very low	136 Å²	136	139.2 Å²	139.2	88%	0.883	80%	0.799	S	S	*	*	P	Polyproline II helix	trans	-64.7	125	-164.9	25.5	-33.1	0	0	0	111.8	S577	P575-S577 PolarHBondContact O-N 2.84Å
576	R	26.3	Very low	28.5	Very low	225 Å²	225	141 Å²	141	85%	0.849	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-63.3	125.9	166.5	-80.6	179.7	174	178.9	-2.6	108.8	G574	G574-R576 PolarHBondContact O-N 3.44Å
577	S	27.7	Very low	28.4	Very low	114 Å²	114	133.5 Å²	133.5	80%	0.797	81%	0.814	S	S	*	*	P	Polyproline II helix	trans	-64	135.4	171.8	51.7	0	0	0	0	110.7	P575 K579	P575-S577 PolarHBondContact O-N 2.84Å; S577-K579 PolarHBondContact O-N 3.4Å
578	H	26.2	Very low	28.2	Very low	184 Å²	184	136.9 Å²	136.9	85%	0.852	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-59.7	127.9	163.9	-89.4	-89.6	0	0	0	109.9
579	K	26.5	Very low	28	Very low	204 Å²	204	140.6 Å²	140.6	89%	0.887	82%	0.818	S	S	*	*			trans	-138.1	111.2	147.8	-115.2	-177	179.5	-178	0	107.9	S577	S577-K579 PolarHBondContact O-N 3.4Å
580	E	26.1	Very low	27.4	Very low	187 Å²	187	139.6 Å²	139.6	87%	0.874	82%	0.819	S	S	*	*			trans	-60.6	137.6	166.6	-67.5	173.1	144.3	0	0	109.8
581	S	26.3	Very low	27.9	Very low	120 Å²	120	139 Å²	139	84%	0.839	82%	0.815	S	S	*	*			trans	-160	125.1	141.8	-168.2	0	0	0	0	109.3
582	N	27.4	Very low	27.6	Very low	167 Å²	167	138.9 Å²	138.9	89%	0.893	82%	0.815	S	S	*	*			trans	-60.8	160.5	174.1	-73.9	-35.4	0	0	0	112.6
583	G	26.9	Very low	27.2	Very low	73 Å²	73	140.1 Å²	140.1	75%	0.753	81%	0.81	S	S	*	*			trans	130.8	102.5	144.3	0	0	0	0	0	116.2
584	T	25.1	Very low	26.9	Very low	146 Å²	146	138.9 Å²	138.9	90%	0.896	80%	0.804	S	S	*	*			trans	-37.8	137.9	156.1	44.4	0	0	0	0	115.6
585	A	27.5	Very low	26.7	Very low	101 Å²	101	143.8 Å²	143.8	84%	0.835	81%	0.811	S	S	*	*				178.7	133.2	126.2	0	0	0	0	0	113.5
586	S	25.3	Very low	26.5	Very low	130 Å²	130	142.2 Å²	142.2	91%	0.909	80%	0.799	S	S	*	*			trans	-13.9	146.5	153.7	-171.6	0	0	0	0	119.6
587	G	25.8	Very low	26.4	Very low	73 Å²	73	139 Å²	139	75%	0.753	79%	0.794	S	S	*	*			trans	161.3	108.2	153.4	0	0	0	0	0	115.5
588	Q	24.6	Very low	26.3	Very low	182 Å²	182	143.2 Å²	143.2	85%	0.85	79%	0.792	S	S	*	*			trans	-59.3	145.7	172.1	-66.6	161.9	-38.9	0	0	113.2
589	H	25.3	Very low	26.2	Very low	186 Å²	186	141.7 Å²	141.7	86%	0.861	79%	0.79	S	S	*	*				174.8	119.5	123.5	-102.7	-74.9	0	0	0	112.5
590	T	23.7	Very low	26.2	Very low	125 Å²	125	139.5 Å²	139.5	77%	0.767	79%	0.787	S	S	*	*			trans	-80.1	179.7	157.3	10.5	0	0	0	0	110.1
591	P	42.9	Very low	26.7	Very low	102 Å²	102	135.7 Å²	135.7	66%	0.662	78%	0.778	S	S	*	*			cis	-139.3	-166.3	-43.7	36.7	-17.7	0	0	0	112.5
592	S	23.4	Very low	26.7	Very low	101 Å²	101	137.3 Å²	137.3	71%	0.706	78%	0.778	S	S	*	*			trans	82.6	146.3	152.1	75.9	0	0	0	0	116.6
593	Q	24.2	Very low	26.7	Very low	152 Å²	152	133.5 Å²	133.5	71%	0.71	77%	0.769	S	S	*	*			cis	-171.2	152.2	19	-137.2	168.5	10.3	0	0	108.8
594	Q	24.1	Very low	26.6	Very low	151 Å²	151	137.3 Å²	137.3	71%	0.706	77%	0.772	S	S	*	*			trans	66.2	144.8	146.4	-82.8	167.1	-6.3	0	0	118.5
595	Q	25.7	Very low	26.6	Very low	160 Å²	160	135 Å²	135	75%	0.748	76%	0.762	S	S	*	*			cis	-170.2	145	33.1	-124.1	167.7	-16.5	0	0	109.7
596	T	24.8	Very low	26.5	Very low	104 Å²	104	141.9 Å²	141.9	64%	0.638	77%	0.767	S	S	*	*			trans	59.8	104.6	130.8	-51	0	0	0	0	119.7
597	E	25.1	Very low	26.5	Very low	157 Å²	157	142 Å²	142	73%	0.734	76%	0.761	S	S	*	*				73	112.9	86.1	-153	-173.3	-129.5	0	0	113.7
598	R	24.6	Very low	26.6	Very low	203 Å²	203	146 Å²	146	77%	0.766	76%	0.764	S	S	*	*				160.1	131.6	129	-89.7	173.7	-165.3	-154.1	7	115.4
599	L	25	Very low	26.7	Very low	152 Å²	152	145.7 Å²	145.7	80%	0.796	76%	0.763	S	S	*	*			trans	65.8	109.7	133	-67.5	153.9	0	0	0	120.8
600	L	25.8	Very low	26.8	Very low	157 Å²	157	147.9 Å²	147.9	82%	0.822	77%	0.765	S	S	*	*			trans	-59.9	164.3	143.2	-77.2	160.4	0	0	0	110.2
601	P	38.1	Very low	27	Very low	108 Å²	108	150.7 Å²	150.7	70%	0.701	77%	0.769	S	S	*	*			cis	-152.2	-177.6	35	40.4	-17.2	0	0	0	119
602	D	25.9	Very low	26.5	Very low	154 Å²	154	152.1 Å²	152.1	82%	0.824	78%	0.777	S	S	*	*			trans	93.2	123.9	145	-83	-20.1	0	0	0	124.4
603	A	26.3	Very low	26.8	Very low	87 Å²	87	152 Å²	152	72%	0.719	78%	0.781	S	S	*	*			trans	48.6	118.3	140.9	0	0	0	0	0	120.7
604	D	25.4	Very low	27.2	Very low	152 Å²	152	155.2 Å²	155.2	81%	0.813	81%	0.811	S	S	*	*				-159.5	142.6	112.1	-128.9	-22.1	0	0	0	114
605	S	25	Very low	27.3	Very low	99 Å²	99	155.5 Å²	155.5	69%	0.692	82%	0.816	S	S	*	*			trans	-70.5	140.2	173.3	43.5	0	0	0	0	112.5
606	R	25.6	Very low	27.4	Very low	244 Å²	244	155.2 Å²	155.2	92%	0.921	82%	0.82	S	S	*	*			trans	-155.4	123.8	151.2	-107	168.7	-147	-148.5	6.5	112.8
607	V	24.6	Very low	27.6	Very low	132 Å²	132	158.1 Å²	158.1	80%	0.8	83%	0.83	S	S	*	*			trans	-63.4	138.7	166.8	172.3	0	0	0	0	109.5
608	I	28.4	Very low	27.7	Very low	157 Å²	157	158.1 Å²	158.1	81%	0.805	84%	0.836	S	S	*	*			trans	-133.9	117.4	159.6	-62.4	-176.6	0	0	0	108.4
609	E	27.1	Very low	27.9	Very low	176 Å²	176	155.3 Å²	155.3	82%	0.822	84%	0.84	S	S	*	*			trans	-64.7	144.1	170.3	-72.9	169.8	136.4	0	0	111.2
610	Y	27.2	Very low	28.1	Very low	232 Å²	232	155.5 Å²	155.5	91%	0.91	84%	0.843	S	S	*	*			trans	-97.2	113.7	165.9	-94.1	-86.5	0	0	0	109.1
611	E	28.2	Very low	28.3	Very low	185 Å²	185	155.4 Å²	155.4	86%	0.864	84%	0.844	S	S	*	*			trans	-88.8	142.6	164.4	-147.9	172.6	-168.3	0	0	109.7
612	T	32	Very low	27.5	Very low	132 Å²	132	159.1 Å²	159.1	81%	0.81	86%	0.855	S	S	*	*			trans	-60	148.7	-177.4	36.9	0	0	0	0	115.8
613	A	29.2	Very low	27.6	Very low	97 Å²	97	159.5 Å²	159.5	80%	0.802	86%	0.858	S	S	*	*				-173.2	133.5	128.9	0	0	0	0	0	113.4
614	V	32.8	Very low	27.8	Very low	221 Å²	221	166.1 Å²	166.1	100%	1.339	87%	0.871	S	S	*	*			trans	76.2	0	167.2	-161.9	0	0	0	0	118.5

Retrieved 614 of 614 residues in 366.1 ms (Link to these results)

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