A0A087YD01_POEFO Loading...

Transmembrane protein 87B

AlphaFold DB , UniProt , Accession A0A087YD01, Species POEFO (Poecilia formosa, Amazon molly), Gene TMEM87B, Length 563 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M39Very low30.8Very low245 Ų245169.8 Ų169.8100%1.20789%0.891SS**  0117.90-68.9172.2179.100108.2
2A30.5Very low31.1Very low106 Ų106162.3 Ų162.388%0.87686%0.862SS**  trans166.892.1160.500000108.7
3T30.8Very low32Very low139 Ų139158.8 Ų158.885%0.85385%0.854SS**  trans-88.9108.9171.528.40000109.5V5T3-V5 PolarHBondContact O-N 3.37Å
4A30.9Very low32.6Very low105 Ų105153.4 Ų153.487%0.86883%0.829SS**  trans-75.2114177.300000110.9R6A4-R6 PolarHBondContact O-N 2.67Å
5V32.9Very low32.9Very low138 Ų138151.7 Ų151.784%0.83682%0.819SS**  trans-79.6116.5174.7175.90000109.7T3 M7T3-V5 PolarHBondContact O-N 3.37Å; V5-M7 PolarHBondContact O-N 3.13Å
6R28.7Very low33.4Very low240 Ų240145.9 Ų145.991%0.90681%0.806SS**  trans-72.1102.3180-167.6-179.7-161.6172.35.9110.5A4 R8A4-R6 PolarHBondContact O-N 2.67Å; R6-R8 PolarHBondContact O-N 3.28Å; R6-R8 VanDerWaalsContact O-N 3.14Å
7M27.8Very low34.2Very low178 Ų178143.1 Ų143.188%0.87779%0.793SS**  trans-59.7117.2169.9-85.6-175.7176.200110.1V5 T9V5-M7 PolarHBondContact O-N 3.13Å; M7-T9 PolarHBondContact O-N 3.16Å
8R27.8Very low34.9Very low232 Ų232140.1 Ų140.188%0.87577%0.774SS**  trans-90.494.5176.3-163.1178.4-162.21734.5108.5R6 W10R6-R8 PolarHBondContact O-N 3.28Å; R6-R8 VanDerWaalsContact O-N 3.14Å; R8-W10 PolarHBondContact O-N 3.43Å; R8-W10 VanDerWaalsContact O-N 3.09Å
9T30.5Very low35.3Very low131 Ų131141.8 Ų141.880%0.80477%0.769SS**  trans-58.6111.6174.448.40000110.2M7 S11M7-T9 PolarHBondContact O-N 3.16Å; T9-S11 PolarHBondContact O-N 3.34Å; T9-S11 VanDerWaalsContact O-N 3.11Å
10W28.3Very low36Very low242 Ų242138.3 Ų138.392%0.91775%0.754SS**  trans-71.4100.2169.7-107.844.6000108.9R8 C12R8-W10 PolarHBondContact O-N 3.43Å; R8-W10 VanDerWaalsContact O-N 3.09Å; W10-C12 PolarHBondContact O-N 3.48Å
11S32.1Very low36.4Very low112 Ų112137.4 Ų137.478%0.78374%0.74SS**  trans-68.6120.6166.6-176.40000108.6T9 P13T9-S11 PolarHBondContact O-N 3.34Å; T9-S11 VanDerWaalsContact O-N 3.11Å; S11-P13 WeakPolarHBondContact O-CD 3.01Å
12C34.4Very low36.9Very low80 Ų80131.2 Ų131.254%0.54171%0.709SS.*  trans-94.3110.9178.7-163.50000109.3W10 T14W10-C12 PolarHBondContact O-N 3.48Å; C12-T14 PolarHBondContact O-N 2.88Å; C12-T14 VanDerWaalsContact O-N 3.11Å; C12-T14 PolarHBondContact SG-OG1 3.24Å; C12-T14 VanDerWaalsContact SG-OG1 3.39Å
13P41.9Very low37.9Very low117 Ų117129.2 Ų129.276%0.7669%0.686SS**THydrogen-bonded Turntrans-72.6-4.7-170.427.4-33.5000114.5S11S11-P13 WeakPolarHBondContact O-CD 3.01Å
14T40.8Very low38.7Very low83 Ų83128.1 Ų128.151%0.50967%0.67SS.*THydrogen-bonded Turntrans-80.1-15.2-178.553.20000114.2C12 G16 V17 I18C12-T14 PolarHBondContact O-N 2.88Å; C12-T14 VanDerWaalsContact O-N 3.11Å; C12-T14 PolarHBondContact SG-OG1 3.24Å; C12-T14 VanDerWaalsContact SG-OG1 3.39Å; T14-G16 VanDerWaalsContact C-N 3.29Å; T14-G16 PolarHBondContact O-N 3.45Å; T14-V17 PolarHBondContact O-N 3.09Å; T14-I18 WeakPolarHBondContact O-CG1 3.31Å
15L37.6Very low39.7Very low128 Ų128125 Ų12567%0.6764%0.637SS**Hα-helixtrans-66.7-31.2-176.4-148.974.8000112.7V17 I18 Y19L15-V17 VanDerWaalsContact C-N 3.31Å; L15-V17 PolarHBondContact O-N 3.43Å; L15-I18 PolarHBondContact O-N 3.14Å; L15-Y19 PolarHBondContact O-N 3.1Å; L15-Y19 VanDerWaalsContact O-N 3.17Å
16G39.8Very low40.6Very low59 Ų59122.8 Ų122.861%0.60862%0.623SS**Hα-helixtrans-70.8-19.2-179.100000115.2T14 P20T14-G16 VanDerWaalsContact C-N 3.29Å; T14-G16 PolarHBondContact O-N 3.45Å; G16-P20 WeakPolarHBondContact O-CD 3.47Å; G16-P20 WeakPolarHBondContact O-CG 3.31Å
17V47.4Very low41.6Very low98 Ų98115.4 Ų115.459%0.59460%0.604SS**Hα-helixtrans-91.4-33.5175.5-1770000111.1T14 L15 P20 W21T14-V17 PolarHBondContact O-N 3.09Å; L15-V17 VanDerWaalsContact C-N 3.31Å; L15-V17 PolarHBondContact O-N 3.43Å; V17-P20 WeakPolarHBondContact O-CD 3.26Å; V17-P20 WeakPolarHBondContact O-CG 3.3Å; V17-W21 VanDerWaalsContact O-CD1 3.27Å
18I46.5Very low42.6Very low89 Ų89108.4 Ų108.446%0.45657%0.571SS.*Hα-helixtrans-71.4-37.8179.9-62166000111.1T14 L15 W21 M22T14-I18 WeakPolarHBondContact O-CG1 3.31Å; L15-I18 PolarHBondContact O-N 3.14Å; I18-W21 PolarHBondContact O-N 3.13Å; I18-M22 HydrophobicContact CG2-CG 3.89Å; I18-M22 WeakPolarHBondContact O-CB 3.29Å; I18-M22 VanDerWaalsContact O-CG 3.29Å; I18-M22 WeakPolarHBondContact O-CG 3.36Å; I18-M22 PolarHBondContact O-N 3.18Å
19Y43.2Very low43.5Very low172 Ų172101.1 Ų101.168%0.67555%0.549SS*.Hα-helixtrans-59.9-51.7-178.2-163-97.5000114.5L15 W21 M22 V23L15-Y19 PolarHBondContact O-N 3.1Å; L15-Y19 VanDerWaalsContact O-N 3.17Å; Y19-W21 VanDerWaalsContact C-N 3.3Å; Y19-W21 PolarHBondContact O-N 3.19Å; Y19-M22 PolarHBondContact O-N 3.05Å; Y19-V23 HydrophobicContact CD1-CG2 4.16Å; Y19-V23 HydrophobicContact CE1-CG2 3.92Å; Y19-V23 WeakPolarHBondContact O-CG2 3.1Å; Y19-V23 PolarHBondContact O-N 2.95Å
20P48.8Very low43.9Very low71 Ų7198 Ų9846%0.46154%0.543SS..Hα-helixtrans-64.3-32.9176.724.8-34000112.7G16 V17 F24G16-P20 WeakPolarHBondContact O-CD 3.47Å; G16-P20 WeakPolarHBondContact O-CG 3.31Å; V17-P20 WeakPolarHBondContact O-CD 3.26Å; V17-P20 WeakPolarHBondContact O-CG 3.3Å; P20-F24 VanDerWaalsContact O-CB 3.23Å; P20-F24 WeakPolarHBondContact O-CB 3.3Å; P20-F24 PolarHBondContact O-N 3Å
21W45.8Very low44.6Very low121 Ų12191.3 Ų91.346%0.45853%0.528SS..Hα-helixtrans-68.4-39.9173.9-83.571.9000112.5V17 I18 Y19 F24 F25 F348V17-W21 VanDerWaalsContact O-CD1 3.27Å; I18-W21 PolarHBondContact O-N 3.13Å; Y19-W21 VanDerWaalsContact C-N 3.3Å; Y19-W21 PolarHBondContact O-N 3.19Å; W21-F24 PolarHBondContact O-N 3.27Å; W21-F25 VanDerWaalsContact O-CB 3.26Å; W21-F25 WeakPolarHBondContact O-CB 3.31Å; W21-F25 PolarHBondContact O-N 3.03Å; W21-F348 AromaticContact CH2-CE1 3.71Å; W21-F348 HydrophobicContact CH2-CE1 3.71Å; W21-F348 AromaticContact CH2-CZ 3.52Å; W21-F348 HydrophobicContact CH2-CZ 3.52Å; W21-F348 AromaticContact CZ3-CE1 3.72Å; W21-F348 HydrophobicContact CZ3-CE1 3.72Å; W21-F348 HydrophobicContact CZ3-CE2 4.42Å; W21-F348 AromaticContact CZ3-CZ 3.66Å; W21-F348 HydrophobicContact CZ3-CZ 3.66Å
22M48.3Very low44.9Very low114 Ų11487.8 Ų87.856%0.56250%0.502SS*.Hα-helixtrans-64.8-42.5173.8-74.7-76.7-72.300111.8I18 Y19 F25 T26I18-M22 HydrophobicContact CG2-CG 3.89Å; I18-M22 WeakPolarHBondContact O-CB 3.29Å; I18-M22 VanDerWaalsContact O-CG 3.29Å; I18-M22 WeakPolarHBondContact O-CG 3.36Å; I18-M22 PolarHBondContact O-N 3.18Å; Y19-M22 PolarHBondContact O-N 3.05Å; M22-F25 WeakPolarHBondContact O-CB 3.12Å; M22-F25 PolarHBondContact O-N 3.3Å; M22-T26 PolarHBondContact O-N 3.3Å; M22-T26 PolarHBondContact O-OG1 3.29Å
23V51.2Low45Very low64 Ų6491.9 Ų91.939%0.38852%0.519SS..Hα-helixtrans-63.5-46.9175.1172.80000110.3Y19 F25 T26 V27Y19-V23 HydrophobicContact CD1-CG2 4.16Å; Y19-V23 HydrophobicContact CE1-CG2 3.92Å; Y19-V23 WeakPolarHBondContact O-CG2 3.1Å; Y19-V23 PolarHBondContact O-N 2.95Å; V23-F25 VanDerWaalsContact C-N 3.31Å; V23-F25 PolarHBondContact O-N 2.99Å; V23-T26 WeakPolarHBondContact CA-OG1 3.34Å; V23-T26 PolarHBondContact O-N 3.25Å; V23-T26 PolarHBondContact O-OG1 3.49Å; V23-V27 HydrophobicContact CG1-CG2 4.38Å; V23-V27 WeakPolarHBondContact O-CG2 3.5Å; V23-V27 PolarHBondContact O-N 3.41Å
24F49.1Very low45Very low117 Ų11793.6 Ų93.651%0.51352%0.516SS..Hα-helixtrans-57.7-43174.6-171-98.2000111.7P20 W21 T26 V27 L28P20-F24 VanDerWaalsContact O-CB 3.23Å; P20-F24 WeakPolarHBondContact O-CB 3.3Å; P20-F24 PolarHBondContact O-N 3Å; W21-F24 PolarHBondContact O-N 3.27Å; F24-T26 PolarHBondContact O-N 3.42Å; F24-V27 PolarHBondContact O-N 3.14Å; F24-L28 HydrophobicContact CE1-CD1 4.12Å; F24-L28 HydrophobicContact CE1-CD2 4.49Å; F24-L28 HydrophobicContact CZ-CD1 4.09Å; F24-L28 VanDerWaalsContact O-CB 3.31Å; F24-L28 WeakPolarHBondContact O-CB 3.31Å; F24-L28 PolarHBondContact O-N 3.22Å
25F50Low45Very low40 Ų4091.4 Ų91.418%0.17550%0.503CS..Hα-helixtrans-60.7-44.8176.2-163.2-94.1000112.2W21 M22 V23 L29 A347 I351W21-F25 VanDerWaalsContact O-CB 3.26Å; W21-F25 WeakPolarHBondContact O-CB 3.31Å; W21-F25 PolarHBondContact O-N 3.03Å; M22-F25 WeakPolarHBondContact O-CB 3.12Å; M22-F25 PolarHBondContact O-N 3.3Å; V23-F25 VanDerWaalsContact C-N 3.31Å; V23-F25 PolarHBondContact O-N 2.99Å; F25-L29 HydrophobicContact CD1-CD1 3.64Å; F25-L29 HydrophobicContact CE1-CD1 3.49Å; F25-L29 VanDerWaalsContact CE1-CD1 3.49Å; F25-L29 HydrophobicContact CZ-CD1 4.29Å; F25-L29 WeakPolarHBondContact O-CB 3.49Å; F25-L29 PolarHBondContact O-N 2.85Å; F25-L29 VanDerWaalsContact O-N 3.13Å; F25-A347 HydrophobicContact CE2-CB 4.33Å; F25-I351 HydrophobicContact CD2-CD1 4.05Å; F25-I351 HydrophobicContact CD2-CG1 3.93Å; F25-I351 HydrophobicContact CE2-CD1 4.36Å; F25-I351 HydrophobicContact CE2-CG1 3.92Å
26T53.6Low45.5Very low91 Ų9190 Ų9056%0.55850%0.5SS*.Hα-helixtrans-68.1-34.1175.851.80000113.4M22 V23 F24 G30M22-T26 PolarHBondContact O-N 3.3Å; M22-T26 PolarHBondContact O-OG1 3.29Å; V23-T26 WeakPolarHBondContact CA-OG1 3.34Å; V23-T26 PolarHBondContact O-N 3.25Å; V23-T26 PolarHBondContact O-OG1 3.49Å; F24-T26 PolarHBondContact O-N 3.42Å; T26-G30 PolarHBondContact O-N 3.14Å; T26-G30 VanDerWaalsContact O-N 3.14Å
27V48.2Very low45.9Very low84 Ų8488.5 Ų88.551%0.50948%0.484SS..Hα-helixtrans-71.5-45.1176.6170.30000110.5V23 F24 L29 G30 T31V23-V27 HydrophobicContact CG1-CG2 4.38Å; V23-V27 WeakPolarHBondContact O-CG2 3.5Å; V23-V27 PolarHBondContact O-N 3.41Å; F24-V27 PolarHBondContact O-N 3.14Å; V27-L29 PolarHBondContact O-N 2.95Å; V27-G30 WeakPolarHBondContact O-CA 3.4Å; V27-G30 PolarHBondContact O-N 3.28Å; V27-T31 PolarHBondContact O-N 3.18Å; V27-T31 VanDerWaalsContact O-N 3.15Å; V27-T31 PolarHBondContact O-OG1 3.01Å
28L49.6Very low46.4Very low32 Ų3285.1 Ų85.117%0.16847%0.465CS..Hα-helixtrans-61.5-43180-153.681000111.8F24 G30 T31 V32 I351F24-L28 HydrophobicContact CE1-CD1 4.12Å; F24-L28 HydrophobicContact CE1-CD2 4.49Å; F24-L28 HydrophobicContact CZ-CD1 4.09Å; F24-L28 VanDerWaalsContact O-CB 3.31Å; F24-L28 WeakPolarHBondContact O-CB 3.31Å; F24-L28 PolarHBondContact O-N 3.22Å; L28-G30 VanDerWaalsContact C-N 3.31Å; L28-G30 PolarHBondContact O-N 3.3Å; L28-T31 PolarHBondContact O-N 3.48Å; L28-T31 PolarHBondContact O-OG1 3.47Å; L28-V32 WeakPolarHBondContact O-CG2 3.15Å; L28-I351 HydrophobicContact CD2-CG1 4.28Å; L28-I351 HydrophobicContact CD2-CG2 3.99Å
29L46.7Very low47.3Very low79 Ų7981.5 Ų81.541%0.41445%0.447SS..Hα-helixtrans-65.8-31.2173.3-82.8162.4000112.9F25 V27 V354F25-L29 HydrophobicContact CD1-CD1 3.64Å; F25-L29 HydrophobicContact CE1-CD1 3.49Å; F25-L29 VanDerWaalsContact CE1-CD1 3.49Å; F25-L29 HydrophobicContact CZ-CD1 4.29Å; F25-L29 WeakPolarHBondContact O-CB 3.49Å; F25-L29 PolarHBondContact O-N 2.85Å; F25-L29 VanDerWaalsContact O-N 3.13Å; V27-L29 PolarHBondContact O-N 2.95Å; L29-V354 HydrophobicContact CD2-CG2 4.04Å
30G39.2Very low48.9Very low66 Ų6674.7 Ų74.768%0.6842%0.422SS*.Hα-helixtrans-78.1-15179.300000115T26 V27 L28T26-G30 PolarHBondContact O-N 3.14Å; T26-G30 VanDerWaalsContact O-N 3.14Å; V27-G30 WeakPolarHBondContact O-CA 3.4Å; V27-G30 PolarHBondContact O-N 3.28Å; L28-G30 VanDerWaalsContact C-N 3.31Å; L28-G30 PolarHBondContact O-N 3.3Å
31T41.7Very low50.5Low100 Ų10073.6 Ų73.661%0.61341%0.414SS*.THydrogen-bonded Turntrans-96.92.3-176.446.40000115.2V27 L28 N33V27-T31 PolarHBondContact O-N 3.18Å; V27-T31 VanDerWaalsContact O-N 3.15Å; V27-T31 PolarHBondContact O-OG1 3.01Å; L28-T31 PolarHBondContact O-N 3.48Å; L28-T31 PolarHBondContact O-OG1 3.47Å; T31-N33 PolarHBondContact O-N 3.36Å
32V40.3Very low52.3Low39 Ų3967.9 Ų67.924%0.23639%0.392CS..  trans-86.296.3-175-173.80000111.2L28 T35 V354 T358L28-V32 WeakPolarHBondContact O-CG2 3.15Å; V32-T35 HydrophobicContact CG1-CG2 4.38Å; V32-V354 HydrophobicContact CG2-CG1 4.03Å; V32-T358 HydrophobicContact CG1-CG2 4.1Å; V32-T358 WeakPolarHBondContact CG1-OG1 3.36Å
33N35Very low54.1Low165 Ų16565.2 Ų65.288%0.88238%0.38SS*.  trans-104.7-14.1177.5-112.111.1000114.6T31T31-N33 PolarHBondContact O-N 3.36Å
34E42.9Very low55.9Low153 Ų15363.9 Ų63.972%0.71537%0.368SS*.  trans-134.4133.2179.9-65.7-172.7155.500110.3T358E34-T358 WeakPolarHBondContact O-CG2 3.22Å
35T40.2Very low57.8Low37 Ų3765.3 Ų65.323%0.22737%0.374CS..  trans-117.7100.8179.653.90000110.7V32 P296 I357V32-T35 HydrophobicContact CG1-CG2 4.38Å; T35-P296 HydrophobicContact CG2-CB 3.92Å; T35-P296 HydrophobicContact CG2-CG 4.46Å; T35-I357 CarbonylContact C-O 3.58Å; T35-I357 HydrophobicContact CG2-CG2 4Å
36V48.8Very low59.6Low99 Ų9965.8 Ų65.860%0.638%0.378SS*.  trans-95.8-14.6-177.7177.90000112.5I357 T358V36-I357 PolarHBondContact N-O 3Å; V36-T358 PolarHBondContact N-O 2.83Å
37G47.1Very low61.3Low28 Ų2864.4 Ų64.429%0.28938%0.375SS..SBendtrans-93.819.4179.900000115.9R356 I357G37-R356 WeakPolarHBondContact CA-O 3.42Å; G37-I357 VanDerWaalsContact CA-O 3.28Å; G37-I357 WeakPolarHBondContact CA-O 3.44Å; G37-I357 PolarHBondContact N-O 3.21Å
38S58.3Low63.1Low26 Ų2660.7 Ų60.718%0.18235%0.353CS..SBendtrans-71.2165.6173.9-91.20000113.1A294 L299S38-A294 VanDerWaalsContact OG-CB 3.28Å; S38-A294 WeakPolarHBondContact OG-CB 3.45Å; S38-L299 WeakPolarHBondContact OG-CD2 3.43Å
39P66.1Low64.8Low13 Ų1362.2 Ų62.28%0.08436%0.364CS..SBendtrans-50.4143.5159.620.4-30000111.2T41 E228 Y285 T288 A294P39-T41 PolarHBondContact O-N 2.81Å; P39-T41 VanDerWaalsContact O-N 3.08Å; P39-E228 VanDerWaalsContact CA-OE1 3.27Å; P39-E228 WeakPolarHBondContact CA-OE1 3.37Å; P39-E228 WeakPolarHBondContact CB-OE2 3.39Å; P39-Y285 HydrophobicContact CB-CE1 4.05Å; P39-T288 HydrophobicContact CB-CG2 4.39Å; P39-T288 HydrophobicContact CG-CG2 4.28Å; P39-A294 HydrophobicContact CG-CB 4.04Å
40E76.4Confident66.4Low30 Ų3061.3 Ų61.314%0.1436%0.359CS..  trans-55.5113.9-168.6-75.3-168.4158.700111K59 A60 Y97 S225 E228E40-K59 HydrophobicContact CB-CG 4.48Å; E40-K59 PolarHBondContact O-NZ 3.28Å; E40-K59 WeakPolarHBondContact OE2-CA 3.3Å; E40-K59 WeakPolarHBondContact OE2-CG 3.49Å; E40-A60 PolarHBondContact OE2-N 3.2Å; E40-Y97 PolarHBondContact OE1-OH 3.39Å; E40-S225 WeakPolarHBondContact OE2-CB 3.49Å; E40-E228 PolarHBondContact N-OE1 2.83Å; E40-E228 PolarHBondContact N-OE2 3.37Å
41T81.4Confident68Low48 Ų4861.8 Ų61.829%0.29436%0.364SS..  trans-54.6143.6175.936.60000111P39 W44 K59P39-T41 PolarHBondContact O-N 2.81Å; P39-T41 VanDerWaalsContact O-N 3.08Å; T41-W44 WeakPolarHBondContact O-CH2 3.39Å; T41-W44 WeakPolarHBondContact O-CZ2 3.09Å; T41-W44 PolarHBondContact OG1-NE1 2.98Å; T41-K59 PolarHBondContact O-NZ 3.39Å
42G83.4Confident69.6Low1 Ų159.4 Ų59.41%0.0135%0.352CS..SBendtrans-115.5-1.5175.600000112.9M217 G292G42-M217 PolarHBondContact O-N 3.07Å; G42-G292 PolarHBondContact N-O 3.46Å
43L87.6Confident71.4Confident57 Ų5765 Ų6530%0.29838%0.375SS..EExtended strand (participates in β ladder)trans-138126.3-178.7-177.971.7000108.8N214 V215 V216 G292L43-N214 WeakPolarHBondContact CD1-OD1 3.35Å; L43-V215 WeakPolarHBondContact CA-O 3.37Å; L43-V216 HydrophobicContact CD1-CB 4.44Å; L43-V216 HydrophobicContact CD1-CG1 4.13Å; L43-V216 HydrophobicContact CD1-CG2 3.89Å; L43-G292 PolarHBondContact N-O 2.83Å
44W88.8Confident73.5Confident36 Ų3658.6 Ų58.614%0.13634%0.343CS..EExtended strand (participates in β ladder)trans-131135.8176.2-57.5-93.5000110.6T41 I46 L57 K59 N214 V215 M217T41-W44 WeakPolarHBondContact O-CH2 3.39Å; T41-W44 WeakPolarHBondContact O-CZ2 3.09Å; T41-W44 PolarHBondContact OG1-NE1 2.98Å; W44-I46 HydrophobicContact CB-CD1 4.07Å; W44-I46 HydrophobicContact CB-CG1 4.21Å; W44-L57 HydrophobicContact CB-CD1 4.37Å; W44-L57 HydrophobicContact CB-CD2 4.33Å; W44-L57 HydrophobicContact CD2-CD1 3.88Å; W44-L57 HydrophobicContact CD2-CD2 3.75Å; W44-L57 HydrophobicContact CD2-CG 4.35Å; W44-L57 HydrophobicContact CE3-CD1 3.88Å; W44-L57 HydrophobicContact CG-CD1 4.14Å; W44-L57 HydrophobicContact CG-CD2 3.64Å; W44-L57 HydrophobicContact CZ2-CD2 4.38Å; W44-L57 HydrophobicContact CZ3-CD1 4.41Å; W44-K59 HydrophobicContact CH2-CB 4.26Å; W44-K59 HydrophobicContact CH2-CD 4.09Å; W44-N214 CarbonylContact O-C 3.48Å; W44-N214 VanDerWaalsContact O-CA 3.27Å; W44-N214 WeakPolarHBondContact O-CA 3.42Å; W44-N214 PolarHBondContact O-OD1 3.36Å; W44-V215 HydrophobicContact CB-CB 4.45Å; W44-V215 HydrophobicContact CE3-CB 3.99Å; W44-V215 HydrophobicContact CE3-CG1 4.02Å; W44-V215 HydrophobicContact CZ3-CG1 4.29Å; W44-V215 PolarHBondContact N-O 3.38Å; W44-V215 PolarHBondContact O-N 2.92Å; W44-M217 HydrophobicContact CH2-CB 4.49Å; W44-M217 HydrophobicContact CH2-CE 4.09Å; W44-M217 HydrophobicContact CH2-CG 4.26Å; W44-M217 HydrophobicContact CH2-SD 3.59Å; W44-M217 VanDerWaalsContact CH2-SD 3.59Å; W44-M217 HydrophobicContact CZ3-CB 4.11Å; W44-M217 HydrophobicContact CZ3-CE 3.94Å; W44-M217 HydrophobicContact CZ3-CG 3.78Å; W44-M217 HydrophobicContact CZ3-SD 3.66Å
45K89Confident75.5Confident147 Ų14752 Ų5264%0.63931%0.312SS*.EExtended strand (participates in β ladder)trans-122.1103.9175.1-173.4179.1-179.8-177.40108.9T212 V213K45-T212 HydrophobicContact CD-CG2 4.5Å; K45-T212 HydrophobicContact CG-CG2 3.81Å; K45-V213 WeakPolarHBondContact CA-O 3.48Å
46I88.1Confident77.5Confident51 Ų5152.2 Ų52.226%0.26231%0.311SS..EExtended strand (participates in β ladder)trans-120.4131.8-167.4-58.9173.5000109.2W44 I55 L57 T212 V213W44-I46 HydrophobicContact CB-CD1 4.07Å; W44-I46 HydrophobicContact CB-CG1 4.21Å; I46-I55 HydrophobicContact CB-CD1 4.47Å; I46-I55 HydrophobicContact CD1-CG2 3.63Å; I46-I55 HydrophobicContact CG2-CD1 4.29Å; I46-I55 HydrophobicContact CG2-CG1 4.3Å; I46-L57 HydrophobicContact CD1-CD2 4.13Å; I46-T212 CarbonylContact O-C 3.58Å; I46-T212 WeakPolarHBondContact O-CA 3.45Å; I46-V213 PolarHBondContact N-O 3.5Å; I46-V213 PolarHBondContact O-N 2.87Å
47A88.1Confident79.3Confident61 Ų6148 Ų4850%0.50429%0.286SS..EExtended strand (participates in β ladder)trans-87.8124.2171.600000110
48V86Confident81.1Confident6 Ų650 Ų504%0.03629%0.286CS..EExtended strand (participates in β ladder)trans-108.2130.3178.2-170.60000107.5S52 I55 V200 W209 N210 L211 V213V48-S52 VanDerWaalsContact CG1-OG 3.24Å; V48-S52 WeakPolarHBondContact CG1-OG 3.43Å; V48-I55 HydrophobicContact CG2-CD1 3.75Å; V48-I55 HydrophobicContact CG2-CG1 4.33Å; V48-V200 HydrophobicContact CG1-CB 4.22Å; V48-V200 HydrophobicContact CG1-CG2 4.1Å; V48-W209 HydrophobicContact CB-CZ3 4.19Å; V48-W209 HydrophobicContact CG1-CH2 3.8Å; V48-W209 HydrophobicContact CG1-CZ3 3.82Å; V48-W209 WeakPolarHBondContact O-CZ3 3.37Å; V48-N210 WeakPolarHBondContact O-CA 3.42Å; V48-L211 HydrophobicContact CB-CB 4.46Å; V48-L211 WeakPolarHBondContact CB-O 3.05Å; V48-L211 PolarHBondContact N-O 3.45Å; V48-L211 PolarHBondContact O-N 3.11Å; V48-V213 HydrophobicContact CG2-CB 4.47Å; V48-V213 HydrophobicContact CG2-CG2 3.8Å
49V85.1Confident82.5Confident65 Ų6549 Ų4939%0.39428%0.278SS..EExtended strand (participates in β ladder)trans-130.6165.8-178.2-66.70000109.4G51 S52 N210V49-G51 PolarHBondContact O-N 3.3Å; V49-S52 VanDerWaalsContact O-CB 3.31Å; V49-S52 WeakPolarHBondContact O-CB 3.2Å; V49-S52 PolarHBondContact O-N 3.18Å; V49-S52 PolarHBondContact O-OG 3.07Å; V49-N210 HydrophobicContact CG1-CB 4.28Å
50N81Confident83.6Confident60 Ų6048.4 Ų48.432%0.32128%0.275SS..THydrogen-bonded Turntrans-56.9128.7177.1-167.39.5000111.3N205 A207 W209N50-N205 PolarHBondContact ND2-O 3.17Å; N50-A207 PolarHBondContact ND2-O 3.17Å; N50-W209 HydrophobicContact CB-CZ2 4.39Å
51G72.4Confident84.2Confident76 Ų7647.1 Ų47.178%0.78427%0.269SS*.THydrogen-bonded Turntrans794.1-175.400000116.3V49V49-G51 PolarHBondContact O-N 3.3Å
52S76.4Confident84.7Confident50 Ų5046.3 Ų46.335%0.3526%0.261SS..PPolyproline II helixtrans-65.2145.7176.364.10000112.6V48 V49V48-S52 VanDerWaalsContact CG1-OG 3.24Å; V48-S52 WeakPolarHBondContact CG1-OG 3.43Å; V49-S52 VanDerWaalsContact O-CB 3.31Å; V49-S52 WeakPolarHBondContact O-CB 3.2Å; V49-S52 PolarHBondContact O-N 3.18Å; V49-S52 PolarHBondContact O-OG 3.07Å
53E77.1Confident85.1Confident155 Ų15551.4 Ų51.472%0.72428%0.283SS*.PPolyproline II helixtrans-56.8152.1169.7-70.2-174.918000111.8
54P80.2Confident85.2Confident32 Ų3253.2 Ų53.221%0.20829%0.29CS..PPolyproline II helixtrans-60.1142174.126-33.7000110.6I56 Y104 V197 V198 K199P54-I56 PolarHBondContact O-N 3.28Å; P54-Y104 HydrophobicContact CG-CE1 3.86Å; P54-Y104 WeakPolarHBondContact CG-OH 3.42Å; P54-V197 HydrophobicContact CB-CG1 4.17Å; P54-V198 WeakPolarHBondContact CA-O 3.47Å; P54-K199 HydrophobicContact CB-CB 4.32Å
55I84.4Confident85.2Confident14 Ų1451.7 Ų51.77%0.07229%0.285CS..EExtended strand (participates in β ladder)trans-68.9128.5175.3-58.7174.3000108I46 V48 L57 V197 V198 V213I46-I55 HydrophobicContact CB-CD1 4.47Å; I46-I55 HydrophobicContact CD1-CG2 3.63Å; I46-I55 HydrophobicContact CG2-CD1 4.29Å; I46-I55 HydrophobicContact CG2-CG1 4.3Å; V48-I55 HydrophobicContact CG2-CD1 3.75Å; V48-I55 HydrophobicContact CG2-CG1 4.33Å; I55-L57 HydrophobicContact CG2-CD1 3.97Å; I55-L57 HydrophobicContact CG2-CD2 4.33Å; I55-L57 HydrophobicContact CG2-CG 3.8Å; I55-V197 CarbonylContact O-C 3.57Å; I55-V197 VanDerWaalsContact O-CA 3.28Å; I55-V197 WeakPolarHBondContact O-CA 3.5Å; I55-V198 HydrophobicContact CB-CB 4.2Å; I55-V198 PolarHBondContact N-O 3.18Å; I55-V198 PolarHBondContact O-N 2.95Å; I55-V213 HydrophobicContact CD1-CB 4.37Å; I55-V213 HydrophobicContact CD1-CG1 4.48Å
56I82.8Confident85.3Confident41 Ų4146.4 Ų46.421%0.2126%0.264CS..EExtended strand (participates in β ladder)trans-121.6119.7177.2-55.2164.2000107.4P54 Y104 L195P54-I56 PolarHBondContact O-N 3.28Å; I56-Y104 HydrophobicContact CD1-CD1 3.56Å; I56-Y104 HydrophobicContact CD1-CD2 3.46Å; I56-Y104 VanDerWaalsContact CD1-CD2 3.46Å; I56-Y104 HydrophobicContact CD1-CE1 3.73Å; I56-Y104 HydrophobicContact CD1-CE2 3.62Å; I56-Y104 HydrophobicContact CD1-CG 3.42Å; I56-Y104 VanDerWaalsContact CD1-CG 3.42Å; I56-Y104 HydrophobicContact CG1-CD2 4.4Å; I56-Y104 HydrophobicContact CG1-CE2 4.17Å; I56-L195 HydrophobicContact CG2-CD1 3.76Å
57L85.8Confident85.5Confident12 Ų1244 Ų446%0.06325%0.251CS..EExtended strand (participates in β ladder)trans-128.6129.7-179.9-63.1174.9000110.2W44 I46 I55 L196 V215 M217W44-L57 HydrophobicContact CB-CD1 4.37Å; W44-L57 HydrophobicContact CB-CD2 4.33Å; W44-L57 HydrophobicContact CD2-CD1 3.88Å; W44-L57 HydrophobicContact CD2-CD2 3.75Å; W44-L57 HydrophobicContact CD2-CG 4.35Å; W44-L57 HydrophobicContact CE3-CD1 3.88Å; W44-L57 HydrophobicContact CG-CD1 4.14Å; W44-L57 HydrophobicContact CG-CD2 3.64Å; W44-L57 HydrophobicContact CZ2-CD2 4.38Å; W44-L57 HydrophobicContact CZ3-CD1 4.41Å; I46-L57 HydrophobicContact CD1-CD2 4.13Å; I55-L57 HydrophobicContact CG2-CD1 3.97Å; I55-L57 HydrophobicContact CG2-CD2 4.33Å; I55-L57 HydrophobicContact CG2-CG 3.8Å; L57-L196 HydrophobicContact CB-CB 4.41Å; L57-L196 HydrophobicContact CD1-CD2 4.47Å; L57-L196 PolarHBondContact N-O 2.84Å; L57-L196 PolarHBondContact O-N 3.44Å; L57-V215 HydrophobicContact CD1-CB 3.69Å; L57-V215 HydrophobicContact CD1-CG1 3.66Å; L57-V215 HydrophobicContact CD1-CG2 3.63Å; L57-M217 HydrophobicContact CB-CE 4.09Å
58K85.2Confident85.6Confident70 Ų7042.6 Ų42.630%0.30424%0.236SC..EExtended strand (participates in β ladder)trans-113.3129.6179.471.9-168.1-179.2-158.70109.3Y97 E101K58-Y97 VanDerWaalsContact C-OH 3.28Å; K58-Y97 HydrophobicContact CB-CD2 4.43Å; K58-Y97 HydrophobicContact CB-CE2 3.61Å; K58-Y97 HydrophobicContact CG-CE2 4.46Å; K58-E101 WeakPolarHBondContact CD-OE1 3.34Å; K58-E101 VanDerWaalsContact CE-OE1 3.3Å; K58-E101 WeakPolarHBondContact CE-OE1 3.44Å; K58-E101 VanDerWaalsContact NZ-CD 3.33Å; K58-E101 IonicContact NZ-OE1 2.83Å; K58-E101 PolarHBondContact NZ-OE1 3.13Å; K58-E101 IonicContact NZ-OE2 3.52Å; K58-E101 PolarHBondContact NZ-OE2 3.29Å
59K87.4Confident85.8Confident3 Ų342.4 Ų42.41%0.01324%0.235CC..EExtended strand (participates in β ladder)trans-152.7137.3171.1-164.7178.1-176.264.90111.7E40 T41 W44 M61 Y97 Y194 M217 Y223E40-K59 HydrophobicContact CB-CG 4.48Å; E40-K59 PolarHBondContact O-NZ 3.28Å; E40-K59 WeakPolarHBondContact OE2-CA 3.3Å; E40-K59 WeakPolarHBondContact OE2-CG 3.49Å; T41-K59 PolarHBondContact O-NZ 3.39Å; W44-K59 HydrophobicContact CH2-CB 4.26Å; W44-K59 HydrophobicContact CH2-CD 4.09Å; K59-M61 HydrophobicContact CB-CG 4.14Å; K59-M61 HydrophobicContact CD-CG 4.09Å; K59-M61 HydrophobicContact CG-CG 4.06Å; K59-M61 PolarHBondContact O-N 2.77Å; K59-Y97 WeakPolarHBondContact CA-OH 3.23Å; K59-Y97 PolarHBondContact N-OH 2.98Å; K59-Y194 PolarHBondContact N-O 2.97Å; K59-Y194 PolarHBondContact O-N 2.97Å; K59-M217 HydrophobicContact CB-SD 3.72Å; K59-M217 HydrophobicContact CD-CB 3.77Å; K59-M217 HydrophobicContact CD-SD 3.95Å; K59-M217 HydrophobicContact CG-SD 4.47Å; K59-Y223 WeakPolarHBondContact CE-O 3.34Å; K59-Y223 PolarHBondContact NZ-O 2.87Å
60A88.4Confident86Confident1 Ų144.1 Ų44.11%0.00824%0.237CC..EExtended strand (participates in β ladder)trans-80.3110.7166.700000110E40 Y97 G192 S225 I226 T227E40-A60 PolarHBondContact OE2-N 3.2Å; A60-Y97 PolarHBondContact N-OH 3.14Å; A60-G192 CarbonylContact C-O 3.53Å; A60-G192 WeakPolarHBondContact CA-O 3.35Å; A60-S225 VanDerWaalsContact O-CA 3.23Å; A60-S225 WeakPolarHBondContact O-CA 3.35Å; A60-S225 VanDerWaalsContact O-CB 3.29Å; A60-S225 WeakPolarHBondContact O-CB 3.45Å; A60-I226 HydrophobicContact CB-CG2 3.69Å; A60-I226 PolarHBondContact O-N 2.89Å; A60-T227 HydrophobicContact CB-CG2 3.96Å
61M90.4Very high86.3Confident3 Ų342 Ų422%0.01523%0.227CC..EExtended strand (participates in β ladder)trans-112.6150.6-172.5-66.2-168.5-86.400112.7K59 T65 V67 L88 T188 G192 Y194 M217K59-M61 HydrophobicContact CB-CG 4.14Å; K59-M61 HydrophobicContact CD-CG 4.09Å; K59-M61 HydrophobicContact CG-CG 4.06Å; K59-M61 PolarHBondContact O-N 2.77Å; M61-T65 HydrophobicContact CB-CG2 4.31Å; M61-T65 HydrophobicContact CG-CG2 4.19Å; M61-T65 HydrophobicContact SD-CG2 3.55Å; M61-T65 VanDerWaalsContact SD-CG2 3.55Å; M61-V67 HydrophobicContact CE-CG2 4.15Å; M61-V67 HydrophobicContact SD-CG2 4.31Å; M61-L88 HydrophobicContact CE-CD1 4.25Å; M61-T188 HydrophobicContact CB-CG2 4Å; M61-T188 HydrophobicContact CE-CG2 3.63Å; M61-T188 HydrophobicContact SD-CG2 3.86Å; M61-G192 PolarHBondContact N-O 3.34Å; M61-G192 PolarHBondContact O-N 2.93Å; M61-Y194 HydrophobicContact CB-CD2 3.98Å; M61-Y194 HydrophobicContact CB-CE2 4.49Å; M61-Y194 HydrophobicContact CE-CD1 4.46Å; M61-Y194 HydrophobicContact CE-CD2 4.01Å; M61-Y194 HydrophobicContact CE-CG 3.72Å; M61-M217 HydrophobicContact CE-CG 4.45Å; M61-M217 HydrophobicContact CE-SD 3.79Å; M61-M217 HydrophobicContact SD-CB 3.82Å; M61-M217 HydrophobicContact SD-CG 3.86Å; M61-M217 HydrophobicContact SD-SD 3.71Å
62F90.9Very high87Confident31 Ų3142 Ų4214%0.13621%0.211CC..  trans-71.8156.6164.5-66.9-90.4000110.3T65 T188 H221 I226 W229F62-T65 VanDerWaalsContact O-CB 3.31Å; F62-T65 WeakPolarHBondContact O-CB 3.44Å; F62-T65 PolarHBondContact O-N 3.09Å; F62-T65 PolarHBondContact O-OG1 3.45Å; F62-T188 PolarHBondContact O-OG1 2.99Å; F62-H221 AromaticContact CD1-CD2 3.96Å; F62-H221 AromaticContact CE1-CD2 3.87Å; F62-H221 HydrophobicContact CE2-CB 4.4Å; F62-H221 AromaticContact CZ-CD2 3.96Å; F62-I226 HydrophobicContact CD1-CB 4.33Å; F62-I226 HydrophobicContact CD1-CD1 3.65Å; F62-I226 HydrophobicContact CD1-CG1 4.02Å; F62-I226 HydrophobicContact CD2-CB 4.15Å; F62-I226 HydrophobicContact CE1-CB 4.15Å; F62-I226 HydrophobicContact CE1-CD1 3.77Å; F62-I226 HydrophobicContact CE1-CG1 3.69Å; F62-I226 HydrophobicContact CE2-CB 3.95Å; F62-I226 HydrophobicContact CE2-CG1 4.39Å; F62-I226 HydrophobicContact CG-CB 4.33Å; F62-I226 HydrophobicContact CG-CD1 4.22Å; F62-I226 HydrophobicContact CZ-CB 3.95Å; F62-I226 HydrophobicContact CZ-CD1 4.44Å; F62-I226 HydrophobicContact CZ-CG1 3.89Å; F62-W229 HydrophobicContact CE2-CB 4.44Å; F62-W229 HydrophobicContact CZ-CB 3.9Å; F62-W229 HydrophobicContact CZ-CD2 4.41Å; F62-W229 AromaticContact CZ-CG 3.95Å; F62-W229 HydrophobicContact CZ-CG 3.95Å
63K90.9Very high87.4Confident108 Ų10842.1 Ų42.147%0.4721%0.212SC..THydrogen-bonded Turntrans-57.3147164.2179.5179.4179.2-158.40110.2T65 W189 R190 N191K63-T65 VanDerWaalsContact C-N 3.25Å; K63-T65 PolarHBondContact O-N 3.11Å; K63-W189 WeakPolarHBondContact CD-O 3.43Å; K63-W189 WeakPolarHBondContact CE-O 3.44Å; K63-W189 WeakPolarHBondContact CG-O 3.28Å; K63-R190 WeakPolarHBondContact CA-O 3.22Å; K63-R190 PolarHBondContact N-O 2.91Å; K63-N191 WeakPolarHBondContact CB-OD1 3.36Å; K63-N191 PolarHBondContact N-OD1 3.35Å
64E89.9Confident87.8Confident95 Ų9537 Ų3744%0.44419%0.188SC..THydrogen-bonded Turntrans60.532.4-177.1-64.8152.4-142.600113.4T188 K220E64-T188 PolarHBondContact N-O 3.38Å; E64-T188 PolarHBondContact N-OG1 2.94Å; E64-K220 IonicContact OE2-NZ 2.77Å; E64-K220 PolarHBondContact OE2-NZ 3.42Å
65T90.3Very high88.1Confident5 Ų538.9 Ų38.93%0.03120%0.201CC..  trans-83.7129.2166.8-63.20000109.1M61 F62 K63 T187 T188M61-T65 HydrophobicContact CB-CG2 4.31Å; M61-T65 HydrophobicContact CG-CG2 4.19Å; M61-T65 HydrophobicContact SD-CG2 3.55Å; M61-T65 VanDerWaalsContact SD-CG2 3.55Å; F62-T65 VanDerWaalsContact O-CB 3.31Å; F62-T65 WeakPolarHBondContact O-CB 3.44Å; F62-T65 PolarHBondContact O-N 3.09Å; F62-T65 PolarHBondContact O-OG1 3.45Å; K63-T65 VanDerWaalsContact C-N 3.25Å; K63-T65 PolarHBondContact O-N 3.11Å; T65-T187 WeakPolarHBondContact O-CA 3.41Å; T65-T188 WeakPolarHBondContact CB-OG1 3.46Å; T65-T188 PolarHBondContact N-OG1 3.4Å; T65-T188 PolarHBondContact O-N 2.95Å
66D90.7Very high88.2Confident35 Ų3538.4 Ų38.419%0.18720%0.199CC..EExtended strand (participates in β ladder)trans-80.8129.4175.6-68.2-36.8000109.4K181 V184 T187 R218D66-K181 IonicContact OD1-NZ 2.92Å; D66-K181 IonicContact OD2-NZ 3.3Å; D66-K181 PolarHBondContact OD2-NZ 3.39Å; D66-V184 HydrophobicContact CB-CG1 4.29Å; D66-V184 HydrophobicContact CB-CG2 4.3Å; D66-T187 VanDerWaalsContact OD1-CG2 3.23Å; D66-T187 WeakPolarHBondContact OD1-CG2 3.41Å; D66-R218 PolarHBondContact N-O 2.75Å; D66-R218 PolarHBondContact O-N 2.93Å
67V91.3Very high88.3Confident0 Ų040.2 Ų40.20%021%0.214CC..EExtended strand (participates in β ladder)trans-101.4109.7170.8-175.80000108.2M61 L88 V184 I185 A186 L196 M217M61-V67 HydrophobicContact CE-CG2 4.15Å; M61-V67 HydrophobicContact SD-CG2 4.31Å; V67-L88 HydrophobicContact CG2-CD2 4.18Å; V67-V184 WeakPolarHBondContact O-CA 3.42Å; V67-I185 HydrophobicContact CB-CG1 4.32Å; V67-I185 HydrophobicContact CG1-CD1 4.04Å; V67-I185 HydrophobicContact CG1-CG1 4.01Å; V67-I185 VanDerWaalsContact O-CG1 3.3Å; V67-I185 WeakPolarHBondContact O-CG1 3.38Å; V67-I185 PolarHBondContact O-N 3.46Å; V67-A186 HydrophobicContact CB-CB 4.45Å; V67-A186 PolarHBondContact N-O 3.17Å; V67-L196 HydrophobicContact CG1-CD2 3.97Å; V67-M217 HydrophobicContact CG1-CG 4.38Å; V67-M217 HydrophobicContact CG2-CG 4.44Å
68V91Very high88.1Confident32 Ų3247 Ų4719%0.19424%0.243CC..EExtended strand (participates in β ladder)trans-100.5130.9-179.3-163.30000109.6N183 V184 V215 V216V68-N183 CarbonylContact C-O 3.6Å; V68-N183 VanDerWaalsContact CA-O 3.31Å; V68-N183 WeakPolarHBondContact CA-O 3.45Å; V68-N183 HydrophobicContact CG1-CB 3.64Å; V68-N183 WeakPolarHBondContact CG1-O 3.49Å; V68-V184 HydrophobicContact CG2-CG2 4.25Å; V68-V215 WeakPolarHBondContact O-CA 3.34Å; V68-V216 HydrophobicContact CB-CB 3.85Å; V68-V216 HydrophobicContact CB-CG2 4.06Å; V68-V216 HydrophobicContact CG2-CB 4.06Å; V68-V216 PolarHBondContact N-O 3.13Å; V68-V216 PolarHBondContact O-N 3.46Å
69L90.8Very high88.2Confident3 Ų350.1 Ų50.12%0.01626%0.258CS..EExtended strand (participates in β ladder)trans-126.1109.5175.9-175.966.3000108.7I84 L145 N183 I185 V198 V213 V215L69-I84 HydrophobicContact CD2-CG2 3.99Å; L69-L145 HydrophobicContact CB-CD1 4Å; L69-L145 HydrophobicContact CD2-CD1 3.55Å; L69-L145 HydrophobicContact CG-CD1 3.7Å; L69-N183 PolarHBondContact N-O 3.11Å; L69-I185 HydrophobicContact CB-CD1 3.88Å; L69-I185 HydrophobicContact CB-CG1 4Å; L69-I185 HydrophobicContact CB-CG2 3.79Å; L69-I185 HydrophobicContact CD2-CD1 4.02Å; L69-I185 HydrophobicContact CD2-CG2 4.29Å; L69-V198 HydrophobicContact CD2-CG1 4.08Å; L69-V198 HydrophobicContact CD2-CG2 4.47Å; L69-V213 HydrophobicContact CD1-CG1 3.33Å; L69-V213 HydrophobicContact CG-CG1 4.33Å; L69-V215 HydrophobicContact CD1-CG2 3.69Å
70K89.6Confident88.2Confident100 Ų10050 Ų5044%0.43526%0.258SS..EExtended strand (participates in β ladder)trans-129.4129.5-175.9-179.1171.6-178.5171.80111.5V72 N183 N214K70-V72 HydrophobicContact CG-CG2 4.39Å; K70-N183 HydrophobicContact CB-CB 4.17Å; K70-N214 PolarHBondContact N-O 3.33Å; K70-N214 PolarHBondContact O-N 3.01Å
71V87.2Confident88.1Confident16 Ų1654.6 Ų54.610%0.09728%0.278CS..EExtended strand (participates in β ladder)trans-77.9124.6167.1-177.20000108.5F74 F142 L211V71-F74 HydrophobicContact CG1-CB 4.32Å; V71-F74 HydrophobicContact CG1-CD1 4.35Å; V71-F142 HydrophobicContact CB-CB 4.02Å; V71-F142 HydrophobicContact CB-CD1 3.64Å; V71-F142 HydrophobicContact CB-CD2 4.35Å; V71-F142 HydrophobicContact CB-CE1 4.16Å; V71-F142 HydrophobicContact CB-CG 3.74Å; V71-F142 HydrophobicContact CG1-CB 4.21Å; V71-F142 HydrophobicContact CG1-CD1 4.26Å; V71-F142 HydrophobicContact CG1-CD2 4.07Å; V71-F142 HydrophobicContact CG1-CG 3.92Å; V71-F142 HydrophobicContact CG2-CD1 3.62Å; V71-F142 HydrophobicContact CG2-CE1 3.63Å; V71-F142 HydrophobicContact CG2-CG 4.15Å; V71-F142 HydrophobicContact CG2-CZ 4.15Å; V71-L211 HydrophobicContact CG1-CD2 4.16Å
72V86.4Confident88Confident75 Ų7554.5 Ų54.546%0.45528%0.277SS..EExtended strand (participates in β ladder)trans-104.4-35.3-174.6175.60000112.3K70 T212 N214K70-V72 HydrophobicContact CG-CG2 4.39Å; V72-T212 PolarHBondContact N-O 2.97Å; V72-N214 HydrophobicContact CG2-CB 3.42Å; V72-N214 VanDerWaalsContact CG2-CB 3.42Å
73S84.8Confident87.8Confident53 Ų5354.4 Ų54.437%0.37128%0.279SS..EExtended strand (participates in β ladder)trans-141.1145.9172.537.30000109.6T212S73-T212 PolarHBondContact O-N 3.41Å; S73-T212 WeakPolarHBondContact OG-CB 3.39Å; S73-T212 PolarHBondContact OG-OG1 3.33Å
74F86.4Confident87.6Confident49 Ų4949.6 Ų49.622%0.21526%0.258CS..EExtended strand (participates in β ladder)trans-143.1149.1-179.753.7-89.9000109.9V71 L139 F142 N210 L211V71-F74 HydrophobicContact CG1-CB 4.32Å; V71-F74 HydrophobicContact CG1-CD1 4.35Å; F74-L139 HydrophobicContact CE2-CB 3.86Å; F74-L139 HydrophobicContact CE2-CD2 4.06Å; F74-L139 HydrophobicContact CE2-CG 4.31Å; F74-L139 WeakPolarHBondContact CE2-O 3.34Å; F74-L139 HydrophobicContact CZ-CB 4.08Å; F74-L139 HydrophobicContact CZ-CD2 3.96Å; F74-L139 HydrophobicContact CZ-CG 4.12Å; F74-L139 WeakPolarHBondContact CZ-O 3.29Å; F74-F142 HydrophobicContact CB-CD2 4.49Å; F74-F142 HydrophobicContact CD1-CB 3.93Å; F74-F142 AromaticContact CD1-CD2 3.96Å; F74-F142 HydrophobicContact CD1-CD2 3.96Å; F74-F142 HydrophobicContact CD1-CG 4.4Å; F74-F142 HydrophobicContact CE1-CB 3.88Å; F74-F142 HydrophobicContact CE1-CD2 4.43Å; F74-F142 HydrophobicContact CG-CD2 4.19Å; F74-N210 CarbonylContact C-O 3.59Å; F74-N210 WeakPolarHBondContact CA-O 3.41Å; F74-L211 HydrophobicContact CB-CD2 3.46Å; F74-L211 VanDerWaalsContact CB-CD2 3.46Å
75S86.4Confident87.5Confident70 Ų7046 Ų4649%0.4924%0.242SC..EExtended strand (participates in β ladder)trans-141.2115.2174.3-177.50000108.6W209 N210S75-W209 VanDerWaalsContact O-CA 3.32Å; S75-W209 WeakPolarHBondContact O-CA 3.38Å; S75-N210 PolarHBondContact N-O 3.49Å; S75-N210 PolarHBondContact O-N 2.98Å
76C85.9Confident87.5Confident4 Ų445.8 Ų45.83%0.02724%0.24CC..  trans-136.183.9-171.9-61.30000109K78 C135 S137C76-K78 CarbonylContact C-O 3.54Å; C76-K78 PolarHBondContact O-N 2.87Å; C76-C135 HydrophobicContact CB-CB 3.88Å; C76-C135 WeakPolarHBondContact CB-SG 3.26Å; C76-C135 WeakPolarHBondContact SG-CB 3.28Å; C76-C135 CovalentContact SG-SG 2.04Å; C76-C135 PolarHBondContact SG-SG 3.33Å; C76-S137 PolarHBondContact O-N 2.85Å; C76-S137 PolarHBondContact O-OG 2.72Å
77P83.6Confident87.3Confident80 Ų8044.1 Ų44.152%0.51923%0.232SC..SBendtrans-63.7-20.3-176.2-20.833.5000114.2S208P77-S208 VanDerWaalsContact CD-O 3.22Å; P77-S208 WeakPolarHBondContact CD-O 3.44Å
78K83.5Confident87.1Confident155 Ų15544.1 Ų44.167%0.67423%0.232SC*.SBendtrans-121.4156168.7-67.8-179.5179.3177.80108.2C76 V80C76-K78 CarbonylContact C-O 3.54Å; C76-K78 PolarHBondContact O-N 2.87Å; K78-V80 PolarHBondContact O-N 3.47Å
79Q86.4Confident86.8Confident135 Ų13542.6 Ų42.663%0.63122%0.222SC*.  trans-66119.9171.3-170.2177.121.700109.4T134 C135Q79-T134 HydrophobicContact CG-CG2 3.78Å; Q79-C135 WeakPolarHBondContact CA-O 3.45Å
80V86.5Confident86.7Confident1 Ų143.9 Ų43.91%0.00623%0.227CC..EExtended strand (participates in β ladder)trans-131.7140.1-179.8-177.30000108.9K78 F82 C135 P202 A207K78-V80 PolarHBondContact O-N 3.47Å; V80-F82 HydrophobicContact CB-CE1 4.27Å; V80-F82 HydrophobicContact CB-CE2 4.02Å; V80-F82 HydrophobicContact CB-CZ 3.71Å; V80-F82 HydrophobicContact CG1-CD1 4.11Å; V80-F82 HydrophobicContact CG1-CE1 3.49Å; V80-F82 VanDerWaalsContact CG1-CE1 3.49Å; V80-F82 HydrophobicContact CG1-CE2 4.06Å; V80-F82 HydrophobicContact CG1-CZ 3.47Å; V80-F82 VanDerWaalsContact CG1-CZ 3.47Å; V80-C135 PolarHBondContact N-O 3.03Å; V80-C135 PolarHBondContact O-N 2.89Å; V80-P202 HydrophobicContact CG1-CB 4.29Å; V80-A207 HydrophobicContact CG2-CB 3.49Å; V80-A207 VanDerWaalsContact CG2-CB 3.49Å
81K88.1Confident86.3Confident96 Ų9639.4 Ų39.442%0.41721%0.208SC..EExtended strand (participates in β ladder)trans-95.7138.4169.5-67.6175.1-175.9171.70109.8I133 D203K81-I133 CarbonylContact C-O 3.58Å; K81-I133 WeakPolarHBondContact CA-O 3.4Å; K81-D203 HydrophobicContact CB-CB 3.79Å; K81-D203 WeakPolarHBondContact O-CB 3.3Å; K81-D203 PolarHBondContact O-N 2.83Å
82F86.6Confident85.8Confident1 Ų140.5 Ų40.50%0.00422%0.215CC..EExtended strand (participates in β ladder)trans-123.7136.9178.6-59.7-70.3000110.5V80 A132 I133 C135 V200 I201 P202 W209 L211V80-F82 HydrophobicContact CB-CE1 4.27Å; V80-F82 HydrophobicContact CB-CE2 4.02Å; V80-F82 HydrophobicContact CB-CZ 3.71Å; V80-F82 HydrophobicContact CG1-CD1 4.11Å; V80-F82 HydrophobicContact CG1-CE1 3.49Å; V80-F82 VanDerWaalsContact CG1-CE1 3.49Å; V80-F82 HydrophobicContact CG1-CE2 4.06Å; V80-F82 HydrophobicContact CG1-CZ 3.47Å; V80-F82 VanDerWaalsContact CG1-CZ 3.47Å; F82-A132 CarbonylContact O-C 3.6Å; F82-A132 WeakPolarHBondContact O-CA 3.47Å; F82-I133 PolarHBondContact N-O 3.42Å; F82-I133 PolarHBondContact O-N 3.48Å; F82-C135 HydrophobicContact CD2-CB 3.92Å; F82-C135 HydrophobicContact CE2-CB 3.51Å; F82-V200 HydrophobicContact CB-CG1 4.22Å; F82-V200 HydrophobicContact CD1-CG1 4.09Å; F82-V200 HydrophobicContact CG-CG1 4.39Å; F82-I201 WeakPolarHBondContact CA-O 3.47Å; F82-P202 HydrophobicContact CD1-CB 3.95Å; F82-P202 HydrophobicContact CE1-CB 3.88Å; F82-W209 HydrophobicContact CE1-CB 4.46Å; F82-W209 AromaticContact CE1-CD1 3.74Å; F82-W209 AromaticContact CE1-CD2 3.48Å; F82-W209 HydrophobicContact CE1-CD2 3.48Å; F82-W209 VanDerWaalsContact CE1-CD2 3.48Å; F82-W209 AromaticContact CE1-CE2 3.48Å; F82-W209 VanDerWaalsContact CE1-CE2 3.48Å; F82-W209 HydrophobicContact CE1-CE3 4.05Å; F82-W209 AromaticContact CE1-CG 3.67Å; F82-W209 HydrophobicContact CE1-CG 3.67Å; F82-W209 HydrophobicContact CE1-CZ2 4.02Å; F82-W209 AromaticContact CE1-NE1 3.65Å; F82-W209 HydrophobicContact CZ-CB 3.81Å; F82-W209 AromaticContact CZ-CD1 3.88Å; F82-W209 AromaticContact CZ-CD2 3.67Å; F82-W209 HydrophobicContact CZ-CD2 3.67Å; F82-W209 HydrophobicContact CZ-CE3 4.16Å; F82-W209 AromaticContact CZ-CG 3.5Å; F82-W209 HydrophobicContact CZ-CG 3.5Å; F82-L211 HydrophobicContact CD1-CD1 4.43Å; F82-L211 HydrophobicContact CD2-CD1 4.11Å; F82-L211 HydrophobicContact CE2-CD1 4.19Å; F82-L211 HydrophobicContact CG-CD1 4.23Å; F82-L211 HydrophobicContact CZ-CD1 4.41Å
83T87.4Confident85.3Confident30 Ų3037.6 Ų37.618%0.18420%0.198CC..EExtended strand (participates in β ladder)trans-107.6123.7168.5-59.70000108.5K129 H130 I201T83-K129 HydrophobicContact CG2-CD 4.14Å; T83-K129 HydrophobicContact CG2-CG 3.5Å; T83-H130 WeakPolarHBondContact CG2-O 3.38Å; T83-I201 PolarHBondContact N-O 3.28Å; T83-I201 PolarHBondContact O-N 3.41Å
84I87.6Confident84.7Confident6 Ų636.5 Ų36.53%0.03119%0.186CC..EExtended strand (participates in β ladder)trans-95.4114.5175-60.1-179.5000107.6L69 H130 I133 L145 V198L69-I84 HydrophobicContact CD2-CG2 3.99Å; I84-H130 PolarHBondContact O-N 2.93Å; I84-I133 HydrophobicContact CD1-CD1 4.48Å; I84-L145 HydrophobicContact CD1-CD1 4.01Å; I84-L145 HydrophobicContact CD1-CD2 4.18Å; I84-V198 HydrophobicContact CG2-CG1 3.94Å
85H87.4Confident83.7Confident20 Ų2037 Ų379%0.09319%0.191CC..EExtended strand (participates in β ladder)trans-108.4126.4175.5-165-177000108.2L115 E127 H128 K199 I201H85-L115 HydrophobicContact CB-CD1 4.43Å; H85-L115 VanDerWaalsContact CE1-CD1 3.48Å; H85-L115 WeakPolarHBondContact CE1-CD1 3.33Å; H85-L115 WeakPolarHBondContact ND1-CD1 3.29Å; H85-L115 WeakPolarHBondContact O-CD2 3.4Å; H85-E127 IonicContact CE1-OE1 3.59Å; H85-E127 WeakPolarHBondContact NE2-CG 3.27Å; H85-E127 IonicContact NE2-OE1 3.45Å; H85-E127 PolarHBondContact NE2-OE1 3.01Å; H85-H128 PolarHBondContact CD2-O 3.32Å; H85-K199 PolarHBondContact N-O 3.4Å; H85-K199 PolarHBondContact O-N 3.1Å; H85-I201 HydrophobicContact CB-CD1 4.3Å
86W88.9Confident82.6Confident0 Ų035.6 Ų35.60%018%0.176CC..EExtended strand (participates in β ladder)trans-135.9153.7178.460.3-98.5000112.7L88 I126 E127 H128 H130 A148 I185 A186 V197 V198W86-L88 HydrophobicContact CE3-CB 4.35Å; W86-L88 HydrophobicContact CZ3-CB 4.08Å; W86-I126 HydrophobicContact CH2-CG2 3.66Å; W86-I126 HydrophobicContact CZ3-CB 4.33Å; W86-I126 HydrophobicContact CZ3-CG2 3.64Å; W86-E127 WeakPolarHBondContact O-CA 3.45Å; W86-H128 HydrophobicContact CD2-CB 4.27Å; W86-H128 HydrophobicContact CH2-CB 3.94Å; W86-H128 HydrophobicContact CZ2-CB 3.52Å; W86-H128 HydrophobicContact CZ3-CB 4.49Å; W86-H128 PolarHBondContact N-O 2.98Å; W86-H128 AromaticContact NE1-CD2 3.87Å; W86-H128 PolarHBondContact O-N 3.28Å; W86-H130 AromaticContact CD1-CD2 3.77Å; W86-H130 AromaticContact CD1-NE2 3.56Å; W86-H130 AromaticContact NE1-CD2 3.58Å; W86-H130 AromaticContact NE1-CE1 3.88Å; W86-H130 AromaticContact NE1-NE2 2.95Å; W86-H130 PolarHBondContact NE1-NE2 3.36Å; W86-A148 HydrophobicContact CH2-CB 4.21Å; W86-A148 HydrophobicContact CZ2-CB 3.97Å; W86-I185 HydrophobicContact CD2-CD1 3.9Å; W86-I185 HydrophobicContact CE3-CD1 4.36Å; W86-I185 HydrophobicContact CG-CD1 4.07Å; W86-I185 HydrophobicContact CZ2-CB 3.83Å; W86-I185 HydrophobicContact CZ2-CD1 4.47Å; W86-I185 WeakPolarHBondContact CZ2-O 3.49Å; W86-A186 HydrophobicContact CH2-CB 3.75Å; W86-A186 HydrophobicContact CZ3-CB 4.03Å; W86-V197 CarbonylContact C-O 3.54Å; W86-V197 WeakPolarHBondContact CA-O 3.45Å; W86-V198 HydrophobicContact CB-CB 4.48Å; W86-V198 HydrophobicContact CB-CG1 4.39Å; W86-V198 HydrophobicContact CB-CG2 4.07Å
87L86.6Confident81.5Confident1 Ų135.5 Ų35.51%0.00518%0.176CC..EExtended strand (participates in β ladder)trans-129.6128.7175.3174.279.9000109L115 D116 C125 I126 E127 L196 V197L87-L115 HydrophobicContact CB-CB 3.92Å; L87-L115 HydrophobicContact CB-CD2 4.41Å; L87-L115 HydrophobicContact CD2-CB 4.26Å; L87-D116 HydrophobicContact CD2-CB 3.51Å; L87-C125 HydrophobicContact CD1-CB 3.94Å; L87-I126 CarbonylContact C-O 3.5Å; L87-I126 WeakPolarHBondContact CA-O 3.32Å; L87-E127 HydrophobicContact CB-CG 4.38Å; L87-E127 HydrophobicContact CD1-CB 3.73Å; L87-E127 HydrophobicContact CD1-CG 4.09Å; L87-L196 CarbonylContact O-C 3.52Å; L87-L196 WeakPolarHBondContact O-CA 3.29Å; L87-V197 HydrophobicContact CB-CB 4.45Å; L87-V197 PolarHBondContact N-O 3.37Å; L87-V197 PolarHBondContact O-N 3.27Å
88L88.1Confident80.4Confident0 Ų035.5 Ų35.50%017%0.171CC..EExtended strand (participates in β ladder)trans-112.6115.9168-178.862.1000108.6M61 V67 W86 C125 I126 A186 W189 Y194 L195 L196M61-L88 HydrophobicContact CE-CD1 4.25Å; V67-L88 HydrophobicContact CG2-CD2 4.18Å; W86-L88 HydrophobicContact CE3-CB 4.35Å; W86-L88 HydrophobicContact CZ3-CB 4.08Å; L88-C125 CarbonylContact O-C 3.58Å; L88-C125 WeakPolarHBondContact O-CA 3.48Å; L88-I126 PolarHBondContact N-O 3.23Å; L88-I126 PolarHBondContact O-N 3.49Å; L88-A186 HydrophobicContact CD2-CB 3.72Å; L88-W189 HydrophobicContact CD2-CH2 4.48Å; L88-W189 HydrophobicContact CD2-CZ3 3.91Å; L88-W189 HydrophobicContact CG-CH2 4.25Å; L88-W189 HydrophobicContact CG-CZ3 4.18Å; L88-Y194 HydrophobicContact CD1-CD1 3.79Å; L88-Y194 HydrophobicContact CD1-CG 4.33Å; L88-Y194 HydrophobicContact CD2-CD1 4.5Å; L88-Y194 HydrophobicContact CG-CD1 3.97Å; L88-Y194 HydrophobicContact CG-CE1 4.45Å; L88-L195 CarbonylContact C-O 3.58Å; L88-L195 WeakPolarHBondContact CA-O 3.37Å; L88-L196 HydrophobicContact CB-CD1 4.34Å; L88-L196 HydrophobicContact CD1-CB 4.26Å; L88-L196 HydrophobicContact CD1-CD1 4.41Å
89K85.6Confident79.1Confident0 Ų032.4 Ų32.40%016%0.162CC..EExtended strand (participates in β ladder)trans-118.7132.2-178.5-176.2166.6-178.11650111.2D116 K118 A121 C125 Y194 L195K89-D116 WeakPolarHBondContact CD-OD1 3.4Å; K89-D116 WeakPolarHBondContact CD-OD2 3.12Å; K89-D116 IonicContact NZ-OD1 2.81Å; K89-D116 PolarHBondContact NZ-OD1 3.39Å; K89-D116 IonicContact NZ-OD2 3.19Å; K89-D116 PolarHBondContact NZ-OD2 3.38Å; K89-K118 PolarHBondContact NZ-O 3.2Å; K89-A121 PolarHBondContact NZ-O 3.44Å; K89-C125 HydrophobicContact CB-CB 4.11Å; K89-C125 HydrophobicContact CG-CB 4.14Å; K89-Y194 CarbonylContact O-C 3.55Å; K89-Y194 WeakPolarHBondContact O-CA 3.45Å; K89-L195 PolarHBondContact N-O 3.48Å; K89-L195 PolarHBondContact O-N 3.21Å
90Y86.8Confident77.9Confident30 Ų3026.3 Ų26.312%0.11813%0.134CC..EExtended strand (participates in β ladder)trans-90.5129.9169.5169.4-103.2000109.6P92 G123 E124 R190 Y194Y90-P92 HydrophobicContact CE1-CB 4.16Å; Y90-G123 WeakPolarHBondContact O-CA 3.38Å; Y90-E124 PolarHBondContact N-O 2.94Å; Y90-E124 PolarHBondContact O-N 2.89Å; Y90-R190 HydrophobicContact CD2-CB 4.41Å; Y90-R190 HydrophobicContact CE2-CB 4.25Å; Y90-Y194 HydrophobicContact CD2-CD2 4.48Å; Y90-Y194 HydrophobicContact CD2-CE1 4.37Å; Y90-Y194 HydrophobicContact CD2-CE2 4.02Å; Y90-Y194 AromaticContact CD2-CZ 3.95Å; Y90-Y194 HydrophobicContact CG-CE1 4.47Å
91H81.9Confident76.5Confident6 Ų630.2 Ų30.23%0.02815%0.152CC..  trans-106.1125.8174.7-72.7-93000110.5P193H91-P193 HydrophobicContact CB-CG 4.45Å; H91-P193 PolarHBondContact N-O 3.45Å; H91-P193 VanDerWaalsContact O-CG 3.26Å; H91-P193 WeakPolarHBondContact O-CG 3.23Å
92P77.5Confident74.9Confident38 Ų3829.7 Ų29.725%0.24715%0.151CC..SBendtrans-78-25.817530.3-32.5000112.7Y90 P122Y90-P92 HydrophobicContact CE1-CB 4.16Å; P92-P122 WeakPolarHBondContact CD-O 3.26Å
93C75.9Confident73.2Confident15 Ų1532.7 Ų32.710%0.10117%0.166CC..  trans-107.1120.8-177.1-55.70000111.3N95 E96 C437C93-N95 PolarHBondContact O-N 3.45Å; C93-E96 HydrophobicContact CB-CG 4.47Å; C93-E96 PolarHBondContact O-N 3.38Å; C93-C437 VanDerWaalsContact CA-SG 3.57Å; C93-C437 HydrophobicContact CB-CB 3.96Å; C93-C437 WeakPolarHBondContact CB-SG 3.46Å; C93-C437 WeakPolarHBondContact SG-CB 3.5Å; C93-C437 CovalentContact SG-SG 2.04Å; C93-C437 PolarHBondContact SG-SG 3.22Å
94Y70.8Confident71.7Confident30 Ų3034 Ų3412%0.11817%0.168CC..Hα-helixtrans-72.5-26.7-175.7-167.4-104.1000114.5E96 Y97 N98 P193 Q438 W441 V444Y94-E96 PolarHBondContact O-N 2.89Å; Y94-Y97 AromaticContact CD2-CD1 3.97Å; Y94-Y97 HydrophobicContact CD2-CD1 3.97Å; Y94-Y97 AromaticContact CE2-CD1 3.59Å; Y94-Y97 HydrophobicContact CE2-CD1 3.59Å; Y94-Y97 AromaticContact CE2-CE1 3.87Å; Y94-Y97 HydrophobicContact CE2-CE1 3.87Å; Y94-Y97 WeakPolarHBondContact O-CB 3.5Å; Y94-Y97 PolarHBondContact O-N 3.28Å; Y94-N98 WeakPolarHBondContact CE1-ND2 3.37Å; Y94-N98 PolarHBondContact O-N 3.12Å; Y94-P193 HydrophobicContact CD2-CB 4.48Å; Y94-P193 HydrophobicContact CD2-CG 4.33Å; Y94-Q438 PolarHBondContact N-O 2.96Å; Y94-Q438 VanDerWaalsContact N-O 3.14Å; Y94-W441 HydrophobicContact CD2-CB 3.83Å; Y94-W441 HydrophobicContact CG-CB 3.89Å; Y94-V444 HydrophobicContact CE1-CG2 4.5Å
95N67.1Low70.1Confident59 Ų5942 Ų4232%0.31620%0.203SC..Hα-helixtrans-60.8-32.1175.1-71.2-10.8000112.5C93 Y97 A435 Q438C93-N95 PolarHBondContact O-N 3.45Å; N95-Y97 VanDerWaalsContact C-N 3.32Å; N95-A435 PolarHBondContact ND2-O 3.1Å; N95-Q438 PolarHBondContact OD1-OE1 3.44Å
96E62Low68.3Low40 Ų4049.9 Ų49.919%0.18723%0.231CC..Hα-helixtrans-74-23.2175-63.4-154.1118.700113C93 Y94 I100 K118C93-E96 HydrophobicContact CB-CG 4.47Å; C93-E96 PolarHBondContact O-N 3.38Å; Y94-E96 PolarHBondContact O-N 2.89Å; E96-I100 WeakPolarHBondContact O-CG1 3.48Å; E96-K118 IonicContact OE1-NZ 2.66Å; E96-K118 PolarHBondContact OE1-NZ 3.3Å
97Y62.9Low66.4Low3 Ų353.7 Ų53.71%0.01226%0.255CS..Hα-helixtrans-78.3-35.8-177.4174.2-100.8000113.2E40 K58 K59 A60 Y94 N95 P193E40-Y97 PolarHBondContact OE1-OH 3.39Å; K58-Y97 VanDerWaalsContact C-OH 3.28Å; K58-Y97 HydrophobicContact CB-CD2 4.43Å; K58-Y97 HydrophobicContact CB-CE2 3.61Å; K58-Y97 HydrophobicContact CG-CE2 4.46Å; K59-Y97 WeakPolarHBondContact CA-OH 3.23Å; K59-Y97 PolarHBondContact N-OH 2.98Å; A60-Y97 PolarHBondContact N-OH 3.14Å; Y94-Y97 AromaticContact CD2-CD1 3.97Å; Y94-Y97 HydrophobicContact CD2-CD1 3.97Å; Y94-Y97 AromaticContact CE2-CD1 3.59Å; Y94-Y97 HydrophobicContact CE2-CD1 3.59Å; Y94-Y97 AromaticContact CE2-CE1 3.87Å; Y94-Y97 HydrophobicContact CE2-CE1 3.87Å; Y94-Y97 WeakPolarHBondContact O-CB 3.5Å; Y94-Y97 PolarHBondContact O-N 3.28Å; N95-Y97 VanDerWaalsContact C-N 3.32Å; Y97-P193 HydrophobicContact CD1-CB 4.2Å; Y97-P193 HydrophobicContact CD2-CB 3.53Å; Y97-P193 HydrophobicContact CE1-CB 4.33Å; Y97-P193 HydrophobicContact CE2-CB 3.65Å; Y97-P193 HydrophobicContact CG-CB 3.79Å
98N60.8Low64.4Low79 Ų7958.5 Ų58.542%0.42229%0.286SS..Hα-helixtrans-69.9-39.6-178.6-74.9-24.9000113.2Y94 I100Y94-N98 WeakPolarHBondContact CE1-ND2 3.37Å; Y94-N98 PolarHBondContact O-N 3.12Å; N98-I100 PolarHBondContact O-N 3.02Å
99N57.4Low62.4Low90 Ų9065.6 Ų65.648%0.48132%0.323SS..THydrogen-bonded Turntrans-91.910.2-171.1-68.35.3000114.6E101 E102 M103N99-E101 PolarHBondContact O-N 2.89Å; N99-E102 PolarHBondContact O-N 3.32Å; N99-M103 HydrophobicContact CB-CE 4.44Å; N99-M103 WeakPolarHBondContact O-CG 3.35Å; N99-M103 PolarHBondContact O-N 3.05Å; N99-M103 VanDerWaalsContact O-N 3.09Å
100I60.3Low60.1Low8 Ų870.8 Ų70.84%0.04136%0.359CS..Hα-helixtrans-63.2-42.2-172-59.5-176.1000112.3E96 N98 M103 Y104 P117 L195E96-I100 WeakPolarHBondContact O-CG1 3.48Å; N98-I100 PolarHBondContact O-N 3.02Å; I100-M103 PolarHBondContact O-N 3.37Å; I100-Y104 WeakPolarHBondContact O-CB 3.42Å; I100-Y104 PolarHBondContact O-N 3.19Å; I100-P117 HydrophobicContact CG2-CG 4.31Å; I100-L195 HydrophobicContact CD1-CD1 3.99Å; I100-L195 HydrophobicContact CD1-CD2 4.16Å; I100-L195 HydrophobicContact CG2-CD1 4.22Å; I100-L195 HydrophobicContact CG2-CD2 4.31Å
101E56.2Low58.2Low82 Ų8273 Ų7338%0.38337%0.368SS..Hα-helixtrans-66.2-40.3-177.2-78.5158.7-144.700112.7K58 N99 Y104 K105K58-E101 WeakPolarHBondContact CD-OE1 3.34Å; K58-E101 VanDerWaalsContact CE-OE1 3.3Å; K58-E101 WeakPolarHBondContact CE-OE1 3.44Å; K58-E101 VanDerWaalsContact NZ-CD 3.33Å; K58-E101 IonicContact NZ-OE1 2.83Å; K58-E101 PolarHBondContact NZ-OE1 3.13Å; K58-E101 IonicContact NZ-OE2 3.52Å; K58-E101 PolarHBondContact NZ-OE2 3.29Å; N99-E101 PolarHBondContact O-N 2.89Å; E101-Y104 PolarHBondContact O-N 2.92Å; E101-K105 PolarHBondContact O-N 2.87Å; E101-K105 VanDerWaalsContact O-N 3.15Å
102E54.9Low56.5Low85 Ų8576 Ų7640%0.39740%0.399SS..Hα-helixtrans-68.8-40.8175.5-156.3-162.9170.500111.1N99 Y104 K105 R106N99-E102 PolarHBondContact O-N 3.32Å; E102-Y104 VanDerWaalsContact C-N 3.32Å; E102-Y104 PolarHBondContact O-N 3.48Å; E102-K105 PolarHBondContact O-N 3.27Å; E102-R106 WeakPolarHBondContact O-CB 3.29Å; E102-R106 WeakPolarHBondContact O-CG 3.42Å; E102-R106 PolarHBondContact O-N 3.29Å; E102-R106 IonicContact OE1-CZ 3.77Å; E102-R106 IonicContact OE1-NE 3.18Å; E102-R106 PolarHBondContact OE1-NE 3.03Å; E102-R106 IonicContact OE1-NH2 2.66Å; E102-R106 PolarHBondContact OE1-NH2 3.02Å
103M51.8Low55.3Low65 Ų6581.6 Ų81.632%0.3242%0.422SS..Hα-helixtrans-63.9-35.3173.8-72.9-166.3-65.900112.7N99 I100 R106 T107N99-M103 HydrophobicContact CB-CE 4.44Å; N99-M103 WeakPolarHBondContact O-CG 3.35Å; N99-M103 PolarHBondContact O-N 3.05Å; N99-M103 VanDerWaalsContact O-N 3.09Å; I100-M103 PolarHBondContact O-N 3.37Å; M103-R106 PolarHBondContact O-N 3.39Å; M103-T107 VanDerWaalsContact O-CB 3.29Å; M103-T107 WeakPolarHBondContact O-CB 3.48Å; M103-T107 PolarHBondContact O-N 3.07Å; M103-T107 PolarHBondContact O-OG1 3.33Å
104Y55.1Low54.4Low57 Ų5784.4 Ų84.422%0.22444%0.436CS..Hα-helixtrans-64-45.1175.7-141-84000111.5P54 I56 I100 E101 E102 T107 P117P54-Y104 HydrophobicContact CG-CE1 3.86Å; P54-Y104 WeakPolarHBondContact CG-OH 3.42Å; I56-Y104 HydrophobicContact CD1-CD1 3.56Å; I56-Y104 HydrophobicContact CD1-CD2 3.46Å; I56-Y104 VanDerWaalsContact CD1-CD2 3.46Å; I56-Y104 HydrophobicContact CD1-CE1 3.73Å; I56-Y104 HydrophobicContact CD1-CE2 3.62Å; I56-Y104 HydrophobicContact CD1-CG 3.42Å; I56-Y104 VanDerWaalsContact CD1-CG 3.42Å; I56-Y104 HydrophobicContact CG1-CD2 4.4Å; I56-Y104 HydrophobicContact CG1-CE2 4.17Å; I100-Y104 WeakPolarHBondContact O-CB 3.42Å; I100-Y104 PolarHBondContact O-N 3.19Å; E101-Y104 PolarHBondContact O-N 2.92Å; E102-Y104 VanDerWaalsContact C-N 3.32Å; E102-Y104 PolarHBondContact O-N 3.48Å; Y104-T107 PolarHBondContact O-N 3.09Å; Y104-P117 HydrophobicContact CD2-CB 3.95Å; Y104-P117 HydrophobicContact CE2-CB 3.95Å; Y104-P117 HydrophobicContact CE2-CG 4.4Å
105K54Low54Low175 Ų17583.2 Ų83.276%0.76143%0.432SS*.Hα-helixtrans-65.5-36.8175.1-71.4177.5179.51740112.9E101 E102 T107E101-K105 PolarHBondContact O-N 2.87Å; E101-K105 VanDerWaalsContact O-N 3.15Å; E102-K105 PolarHBondContact O-N 3.27Å; K105-T107 VanDerWaalsContact C-N 3.34Å
106R50.8Low53.8Low185 Ų18581 Ų8170%0.69842%0.42SS*.Hα-helixtrans-77.6-13.5178-71.9-176.5-175.8-145.87.8114.3E102 M103 P108E102-R106 WeakPolarHBondContact O-CB 3.29Å; E102-R106 WeakPolarHBondContact O-CG 3.42Å; E102-R106 PolarHBondContact O-N 3.29Å; E102-R106 IonicContact OE1-CZ 3.77Å; E102-R106 IonicContact OE1-NE 3.18Å; E102-R106 PolarHBondContact OE1-NE 3.03Å; E102-R106 IonicContact OE1-NH2 2.66Å; E102-R106 PolarHBondContact OE1-NH2 3.02Å; M103-R106 PolarHBondContact O-N 3.39Å; R106-P108 WeakPolarHBondContact O-CD 3.28Å
107T48.9Very low53.5Low80 Ų8081 Ų8149%0.49142%0.424SS..SBendtrans-117.466.3-176.3-39.40000111.1M103 Y104 K105 L109M103-T107 VanDerWaalsContact O-CB 3.29Å; M103-T107 WeakPolarHBondContact O-CB 3.48Å; M103-T107 PolarHBondContact O-N 3.07Å; M103-T107 PolarHBondContact O-OG1 3.33Å; Y104-T107 PolarHBondContact O-N 3.09Å; K105-T107 VanDerWaalsContact C-N 3.34Å; T107-L109 PolarHBondContact O-N 3.38Å
108P43.9Very low53.4Low101 Ų10184.9 Ų84.966%0.65644%0.441SS*.  trans-65.6107178.828.9-34.4000110.2R106 S110R106-P108 WeakPolarHBondContact O-CD 3.28Å; P108-S110 PolarHBondContact O-N 3.1Å; P108-S110 VanDerWaalsContact O-N 3.09Å
109L45.4Very low53.3Low150 Ų15084.3 Ų84.379%0.78544%0.441SS*.  trans52.241.1155.6-81.8148.6000116.3T107 R111T107-L109 PolarHBondContact O-N 3.38Å; L109-R111 PolarHBondContact O-N 3.47Å
110S38.6Very low53.3Low109 Ų10986 Ų8676%0.76245%0.45SS*.  trans-70.939.2167.5-46.50000112.7P108P108-S110 PolarHBondContact O-N 3.1Å; P108-S110 VanDerWaalsContact O-N 3.09Å
111R46Very low53.4Low77 Ų7785.8 Ų85.829%0.29145%0.45SS..  trans-145.9128.9-145.6-158.6148.2-146.3-160.6-9.8115.5L109 N114 L115 D116L109-R111 PolarHBondContact O-N 3.47Å; R111-N114 VanDerWaalsContact CD-O 3.31Å; R111-N114 WeakPolarHBondContact CD-O 3.43Å; R111-N114 PolarHBondContact NE-O 3.5Å; R111-N114 PolarHBondContact NH1-O 2.92Å; R111-N114 PolarHBondContact NH2-O 3.44Å; R111-L115 PolarHBondContact NH1-O 2.91Å; R111-D116 PolarHBondContact NH1-O 3.25Å; R111-D116 PolarHBondContact NH2-O 2.91Å
112G46.5Very low53.9Low67 Ų6784.2 Ų84.269%0.69145%0.447SS*.SBendtrans-74.7-137.3159.500000112
113E51.6Low54.9Low157 Ų15780.8 Ų80.873%0.73443%0.434SS*.SBendtrans-80.1-19.3-167-63.4-173.6110.900116.3
114N58.3Low56.4Low73 Ų7379.5 Ų79.539%0.3943%0.427SS..  trans-69.8148.5-170.6-56.517.2000113.4R111R111-N114 VanDerWaalsContact CD-O 3.31Å; R111-N114 WeakPolarHBondContact CD-O 3.43Å; R111-N114 PolarHBondContact NE-O 3.5Å; R111-N114 PolarHBondContact NH1-O 2.92Å; R111-N114 PolarHBondContact NH2-O 3.44Å
115L61.7Low57.7Low6 Ų677.8 Ų77.83%0.03142%0.423CS..  trans-94.6-23.9-179.8-86.769.2000116.3H85 L87 R111 P117 E127 V197 K199H85-L115 HydrophobicContact CB-CD1 4.43Å; H85-L115 VanDerWaalsContact CE1-CD1 3.48Å; H85-L115 WeakPolarHBondContact CE1-CD1 3.33Å; H85-L115 WeakPolarHBondContact ND1-CD1 3.29Å; H85-L115 WeakPolarHBondContact O-CD2 3.4Å; L87-L115 HydrophobicContact CB-CB 3.92Å; L87-L115 HydrophobicContact CB-CD2 4.41Å; L87-L115 HydrophobicContact CD2-CB 4.26Å; R111-L115 PolarHBondContact NH1-O 2.91Å; L115-P117 WeakPolarHBondContact O-CD 3.43Å; L115-E127 PolarHBondContact N-OE1 3.38Å; L115-E127 VanDerWaalsContact N-OE1 3.11Å; L115-V197 HydrophobicContact CB-CG1 4.36Å; L115-V197 HydrophobicContact CD2-CB 4.4Å; L115-V197 HydrophobicContact CD2-CG1 4.1Å; L115-V197 HydrophobicContact CG-CG1 4.36Å; L115-K199 HydrophobicContact CD2-CB 4.08Å
116D61.8Low59.2Low11 Ų1170.1 Ų70.16%0.05939%0.391CS..  trans-67.5105.9-170.8-176.2-7000116.2L87 K89 R111 K118 P119L87-D116 HydrophobicContact CD2-CB 3.51Å; K89-D116 WeakPolarHBondContact CD-OD1 3.4Å; K89-D116 WeakPolarHBondContact CD-OD2 3.12Å; K89-D116 IonicContact NZ-OD1 2.81Å; K89-D116 PolarHBondContact NZ-OD1 3.39Å; K89-D116 IonicContact NZ-OD2 3.19Å; K89-D116 PolarHBondContact NZ-OD2 3.38Å; R111-D116 PolarHBondContact NH1-O 3.25Å; R111-D116 PolarHBondContact NH2-O 2.91Å; D116-K118 PolarHBondContact O-N 2.9Å; D116-K118 PolarHBondContact OD1-N 3.38Å; D116-K118 VanDerWaalsContact OD1-O 3.1Å; D116-P119 WeakPolarHBondContact O-CD 3.41Å
117P56.8Low60.7Low42 Ų4262.7 Ų62.727%0.27336%0.364SS..SBendtrans-56.3-21.4-171.221.6-32.8000115.8I100 Y104 L115 L195I100-P117 HydrophobicContact CG2-CG 4.31Å; Y104-P117 HydrophobicContact CD2-CB 3.95Å; Y104-P117 HydrophobicContact CE2-CB 3.95Å; Y104-P117 HydrophobicContact CE2-CG 4.4Å; L115-P117 WeakPolarHBondContact O-CD 3.43Å; P117-L195 HydrophobicContact CG-CD2 3.69Å
118K60.9Low62.4Low84 Ų8459 Ų5937%0.36534%0.341SS..  trans-132.695.8163.4-86.4-175.6171.1174.70108.9K89 E96 D116 N120 A121K89-K118 PolarHBondContact NZ-O 3.2Å; E96-K118 IonicContact OE1-NZ 2.66Å; E96-K118 PolarHBondContact OE1-NZ 3.3Å; D116-K118 PolarHBondContact O-N 2.9Å; D116-K118 PolarHBondContact OD1-N 3.38Å; D116-K118 VanDerWaalsContact OD1-O 3.1Å; K118-N120 PolarHBondContact O-N 2.86Å; K118-N120 VanDerWaalsContact O-N 3.11Å; K118-A121 HydrophobicContact CB-CB 3.52Å; K118-A121 HydrophobicContact CD-CB 3.9Å; K118-A121 HydrophobicContact CG-CB 4.41Å; K118-A121 WeakPolarHBondContact O-CB 3.27Å; K118-A121 PolarHBondContact O-N 2.92Å
119P58.7Low64.3Low66 Ų6658.1 Ų58.143%0.42933%0.327SS..THydrogen-bonded Turntrans-63.3-20.1179.926.7-34.3000113.3D116 V155D116-P119 WeakPolarHBondContact O-CD 3.41Å; P119-V155 WeakPolarHBondContact O-CG1 3.35Å
120N56.7Low66.2Low127 Ų12751.3 Ų51.368%0.67929%0.291SS*.THydrogen-bonded Turntrans-101.63.9179.5-56.416.7000112.8K118K118-N120 PolarHBondContact O-N 2.86Å; K118-N120 VanDerWaalsContact O-N 3.11Å
121A63.3Low68.2Low3 Ų350.3 Ų50.33%0.02528%0.284CS..SBendtrans-74.4133.2174.600000110.3K89 K118 G123K89-A121 PolarHBondContact NZ-O 3.44Å; K118-A121 HydrophobicContact CB-CB 3.52Å; K118-A121 HydrophobicContact CD-CB 3.9Å; K118-A121 HydrophobicContact CG-CB 4.41Å; K118-A121 WeakPolarHBondContact O-CB 3.27Å; K118-A121 PolarHBondContact O-N 2.92Å; A121-G123 PolarHBondContact O-N 3.49Å
122P67.1Low70.1Confident49 Ų4949.4 Ų49.432%0.31829%0.293SS..SBendtrans-61.3131.6-179.627.5-34.8000110.1P92 L157P92-P122 WeakPolarHBondContact CD-O 3.26Å; P122-L157 HydrophobicContact CB-CD1 4.2Å
123G74.9Confident71.9Confident13 Ų1347 Ų4713%0.13426%0.264CS..  trans171.3175.7-177.700000112.4Y90 A121 V155Y90-G123 WeakPolarHBondContact O-CA 3.38Å; A121-G123 PolarHBondContact O-N 3.49Å; G123-V155 PolarHBondContact O-N 3.11Å
124E82.9Confident73.6Confident38 Ų3842.1 Ų42.118%0.17825%0.245CC..EExtended strand (participates in β ladder)trans-113138.5172-67.4168.2171.800107.7Y90 P152 R153 W189 R190Y90-E124 PolarHBondContact N-O 2.94Å; Y90-E124 PolarHBondContact O-N 2.89Å; E124-P152 HydrophobicContact CB-CB 4.27Å; E124-R153 CarbonylContact C-O 3.52Å; E124-R153 VanDerWaalsContact CA-O 3.28Å; E124-R153 WeakPolarHBondContact CA-O 3.45Å; E124-W189 HydrophobicContact CB-CZ2 3.94Å; E124-W189 WeakPolarHBondContact O-CZ2 3.26Å; E124-W189 PolarHBondContact OE2-NE1 3.26Å; E124-R190 VanDerWaalsContact CD-NE 3.29Å; E124-R190 IonicContact OE1-CZ 2.68Å; E124-R190 VanDerWaalsContact OE1-CZ 3.29Å; E124-R190 IonicContact OE1-NE 2.65Å; E124-R190 PolarHBondContact OE1-NE 3.45Å; E124-R190 IonicContact OE1-NH2 3.57Å; E124-R190 PolarHBondContact OE1-NH2 2.96Å; E124-R190 WeakPolarHBondContact OE2-CD 3.46Å; E124-R190 IonicContact OE2-CZ 3.38Å; E124-R190 IonicContact OE2-NE 3.63Å; E124-R190 PolarHBondContact OE2-NE 3.31Å; E124-R190 IonicContact OE2-NH2 3.18Å
125C83.7Confident74.8Confident21 Ų2138.6 Ų38.614%0.14223%0.226CC..EExtended strand (participates in β ladder)trans-139.2158.7-179.966.40000113.8L87 L88 K89 R153L87-C125 HydrophobicContact CD1-CB 3.94Å; L88-C125 CarbonylContact O-C 3.58Å; L88-C125 WeakPolarHBondContact O-CA 3.48Å; K89-C125 HydrophobicContact CB-CB 4.11Å; K89-C125 HydrophobicContact CG-CB 4.14Å; C125-R153 PolarHBondContact N-O 2.93Å; C125-R153 PolarHBondContact O-N 3.36Å
126I84Confident75.9Confident14 Ų1439.5 Ų39.57%0.07223%0.233CC..EExtended strand (participates in β ladder)trans-128.6120.6168.8-66.7-179.4000107.1W86 L87 L88 A150 P152 W189W86-I126 HydrophobicContact CH2-CG2 3.66Å; W86-I126 HydrophobicContact CZ3-CB 4.33Å; W86-I126 HydrophobicContact CZ3-CG2 3.64Å; L87-I126 CarbonylContact C-O 3.5Å; L87-I126 WeakPolarHBondContact CA-O 3.32Å; L88-I126 PolarHBondContact N-O 3.23Å; L88-I126 PolarHBondContact O-N 3.49Å; I126-A150 HydrophobicContact CB-CB 4.4Å; I126-A150 HydrophobicContact CD1-CB 4.28Å; I126-A150 HydrophobicContact CG1-CB 4.26Å; I126-A150 HydrophobicContact CG2-CB 3.41Å; I126-A150 VanDerWaalsContact CG2-CB 3.41Å; I126-P152 HydrophobicContact CD1-CG 4.35Å; I126-W189 HydrophobicContact CB-CH2 4.49Å; I126-W189 HydrophobicContact CB-CZ3 4.44Å; I126-W189 HydrophobicContact CD1-CE3 3.88Å; I126-W189 HydrophobicContact CD1-CH2 4.2Å; I126-W189 HydrophobicContact CD1-CZ3 3.51Å; I126-W189 HydrophobicContact CG1-CH2 4Å; I126-W189 HydrophobicContact CG1-CZ3 3.83Å
127E83.6Confident76.7Confident29 Ų2943.1 Ų43.114%0.13626%0.259CS..EExtended strand (participates in β ladder)trans-113.7135.4172.4-164.1159.8-163.900108.1H85 W86 L87 L115 W170H85-E127 IonicContact CE1-OE1 3.59Å; H85-E127 WeakPolarHBondContact NE2-CG 3.27Å; H85-E127 IonicContact NE2-OE1 3.45Å; H85-E127 PolarHBondContact NE2-OE1 3.01Å; W86-E127 WeakPolarHBondContact O-CA 3.45Å; L87-E127 HydrophobicContact CB-CG 4.38Å; L87-E127 HydrophobicContact CD1-CB 3.73Å; L87-E127 HydrophobicContact CD1-CG 4.09Å; L115-E127 PolarHBondContact N-OE1 3.38Å; L115-E127 VanDerWaalsContact N-OE1 3.11Å; E127-W170 VanDerWaalsContact OE2-CZ3 3.25Å; E127-W170 WeakPolarHBondContact OE2-CZ3 3.47Å
128H84.1Confident77.6Confident3 Ų347.5 Ų47.51%0.01428%0.28CS..EExtended strand (participates in β ladder)trans-147.4140.8179.5-177.462000112.2H85 W86 H130 A148 S172 E174H85-H128 PolarHBondContact CD2-O 3.32Å; W86-H128 HydrophobicContact CD2-CB 4.27Å; W86-H128 HydrophobicContact CH2-CB 3.94Å; W86-H128 HydrophobicContact CZ2-CB 3.52Å; W86-H128 HydrophobicContact CZ3-CB 4.49Å; W86-H128 PolarHBondContact N-O 2.98Å; W86-H128 AromaticContact NE1-CD2 3.87Å; W86-H128 PolarHBondContact O-N 3.28Å; H128-H130 AromaticContact CD2-CE1 3.59Å; H128-H130 AromaticContact CD2-ND1 3.73Å; H128-H130 AromaticContact CD2-NE2 3.89Å; H128-H130 AromaticContact NE2-CE1 3.78Å; H128-H130 AromaticContact NE2-ND1 3.54Å; H128-A148 HydrophobicContact CB-CB 4.05Å; H128-S172 PolarHBondContact CE1-O 3.26Å; H128-E174 IonicContact NE2-OE1 2.64Å; H128-E174 PolarHBondContact NE2-OE1 2.98Å
129K84.2Confident78.4Confident81 Ų8145.9 Ų45.935%0.35228%0.275SS..EExtended strand (participates in β ladder)trans-119.2110.4-179.3-173175.7179.3176.50108.7T83T83-K129 HydrophobicContact CG2-CD 4.14Å; T83-K129 HydrophobicContact CG2-CG 3.5Å
130H83.8Confident79Confident8 Ų851.2 Ų51.24%0.03729%0.294CS..  trans-66.1157.9177.9-71.7-68.9000111.9T83 I84 W86 H128 R146 E174T83-H130 WeakPolarHBondContact CG2-O 3.38Å; I84-H130 PolarHBondContact O-N 2.93Å; W86-H130 AromaticContact CD1-CD2 3.77Å; W86-H130 AromaticContact CD1-NE2 3.56Å; W86-H130 AromaticContact NE1-CD2 3.58Å; W86-H130 AromaticContact NE1-CE1 3.88Å; W86-H130 AromaticContact NE1-NE2 2.95Å; W86-H130 PolarHBondContact NE1-NE2 3.36Å; H128-H130 AromaticContact CD2-CE1 3.59Å; H128-H130 AromaticContact CD2-ND1 3.73Å; H128-H130 AromaticContact CD2-NE2 3.89Å; H128-H130 AromaticContact NE2-CE1 3.78Å; H128-H130 AromaticContact NE2-ND1 3.54Å; H130-R146 PolarHBondContact CE1-O 3.48Å; H130-E174 IonicContact CE1-OE1 3.91Å; H130-E174 IonicContact CG-OE1 3Å; H130-E174 IonicContact ND1-OE1 3.27Å; H130-E174 PolarHBondContact ND1-OE1 3.11Å
131S82.3Confident80Confident87 Ų8750.7 Ų50.761%0.60830%0.295SS*.  trans-61.9156.3169.460.90000111.8I133S131-I133 WeakPolarHBondContact O-CG1 3.28Å; S131-I133 PolarHBondContact O-N 3.24Å; S131-I133 VanDerWaalsContact O-N 3.17Å
132A84.5Confident80.8Confident58 Ų5851.5 Ų51.548%0.47930%0.298SS..  trans-68.6112.1-175.200000111.9F82F82-A132 CarbonylContact O-C 3.6Å; F82-A132 WeakPolarHBondContact O-CA 3.47Å
133I85.9Confident81.5Confident18 Ų1852.2 Ų52.29%0.09230%0.303CS..EExtended strand (participates in β ladder)trans-88.5128.9-178.7-54.1176.5000109.3K81 F82 I84 S131 F142 P143 L145K81-I133 CarbonylContact C-O 3.58Å; K81-I133 WeakPolarHBondContact CA-O 3.4Å; F82-I133 PolarHBondContact N-O 3.42Å; F82-I133 PolarHBondContact O-N 3.48Å; I84-I133 HydrophobicContact CD1-CD1 4.48Å; S131-I133 WeakPolarHBondContact O-CG1 3.28Å; S131-I133 PolarHBondContact O-N 3.24Å; S131-I133 VanDerWaalsContact O-N 3.17Å; I133-F142 HydrophobicContact CB-CE1 4.47Å; I133-F142 HydrophobicContact CB-CZ 4.2Å; I133-F142 HydrophobicContact CD1-CE1 3.83Å; I133-F142 HydrophobicContact CD1-CZ 4.32Å; I133-F142 HydrophobicContact CG2-CE1 3.8Å; I133-F142 HydrophobicContact CG2-CE2 4.21Å; I133-F142 HydrophobicContact CG2-CZ 3.59Å; I133-P143 HydrophobicContact CG2-CB 4.33Å; I133-P143 HydrophobicContact CG2-CG 3.87Å; I133-L145 HydrophobicContact CD1-CD2 3.57Å
134T86.1Confident81.7Confident53 Ų5353.7 Ų53.733%0.32532%0.318SS..EExtended strand (participates in β ladder)trans-89.2127.9178.3-570000110.6Q79Q79-T134 HydrophobicContact CG-CG2 3.78Å
135C84.4Confident81.6Confident0 Ų052.3 Ų52.30%031%0.312CS..EExtended strand (participates in β ladder)trans-111.2137.3171.8-168.80000110.3C76 Q79 V80 F82C76-C135 HydrophobicContact CB-CB 3.88Å; C76-C135 WeakPolarHBondContact CB-SG 3.26Å; C76-C135 WeakPolarHBondContact SG-CB 3.28Å; C76-C135 CovalentContact SG-SG 2.04Å; C76-C135 PolarHBondContact SG-SG 3.33Å; Q79-C135 WeakPolarHBondContact CA-O 3.45Å; V80-C135 PolarHBondContact N-O 3.03Å; V80-C135 PolarHBondContact O-N 2.89Å; F82-C135 HydrophobicContact CD2-CB 3.92Å; F82-C135 HydrophobicContact CE2-CB 3.51Å
136S83.4Confident81.6Confident25 Ų2557 Ų5718%0.17533%0.326CS..  trans-147.3163.217359.90000110.2D138 L139S136-D138 PolarHBondContact O-N 3.33Å; S136-L139 WeakPolarHBondContact O-CB 3.4Å; S136-L139 PolarHBondContact O-N 3.03Å
137S79.5Confident81.4Confident86 Ų8658.9 Ų58.960%0.60133%0.334SS*.THydrogen-bonded Turntrans-57.5-28.7176.4-52.40000114C76 L139C76-S137 PolarHBondContact O-N 2.85Å; C76-S137 PolarHBondContact O-OG 2.72Å; S137-L139 VanDerWaalsContact C-N 3.3Å
138D75.8Confident81.2Confident134 Ų13458 Ų5872%0.71733%0.331SS*.THydrogen-bonded Turntrans-83.7-6.5-175.9-40.4-67000113.2S136S136-D138 PolarHBondContact O-N 3.33Å
139L78.4Confident80.6Confident51 Ų5162 Ų6227%0.26735%0.349SS..  trans-77.6125.9-180-164.379.5000109.4F74 S136 S137 V141 F142F74-L139 HydrophobicContact CE2-CB 3.86Å; F74-L139 HydrophobicContact CE2-CD2 4.06Å; F74-L139 HydrophobicContact CE2-CG 4.31Å; F74-L139 WeakPolarHBondContact CE2-O 3.34Å; F74-L139 HydrophobicContact CZ-CB 4.08Å; F74-L139 HydrophobicContact CZ-CD2 3.96Å; F74-L139 HydrophobicContact CZ-CG 4.12Å; F74-L139 WeakPolarHBondContact CZ-O 3.29Å; S136-L139 WeakPolarHBondContact O-CB 3.4Å; S136-L139 PolarHBondContact O-N 3.03Å; S137-L139 VanDerWaalsContact C-N 3.3Å; L139-V141 WeakPolarHBondContact CG-O 3.29Å; L139-F142 HydrophobicContact CD2-CD2 4.28Å
140H71.4Confident79.9Confident178 Ų17859.3 Ų59.382%0.82434%0.341SS*.SBendtrans-95.2-23.9176.4-67.9-54.2000113.9
141V77.5Confident79.4Confident115 Ų11566.9 Ų66.970%0.69738%0.377SS*.SBendtrans-138.4128.4-178.7-178.20000108.9L139L139-V141 WeakPolarHBondContact CG-O 3.29Å
142F79.6Confident79.1Confident20 Ų2065.3 Ų65.39%0.08837%0.365CS..PPolyproline II helixtrans-74.6137.1176.6-158.3-91.8000110.4V71 F74 I133 L139 G144 L211V71-F142 HydrophobicContact CB-CB 4.02Å; V71-F142 HydrophobicContact CB-CD1 3.64Å; V71-F142 HydrophobicContact CB-CD2 4.35Å; V71-F142 HydrophobicContact CB-CE1 4.16Å; V71-F142 HydrophobicContact CB-CG 3.74Å; V71-F142 HydrophobicContact CG1-CB 4.21Å; V71-F142 HydrophobicContact CG1-CD1 4.26Å; V71-F142 HydrophobicContact CG1-CD2 4.07Å; V71-F142 HydrophobicContact CG1-CG 3.92Å; V71-F142 HydrophobicContact CG2-CD1 3.62Å; V71-F142 HydrophobicContact CG2-CE1 3.63Å; V71-F142 HydrophobicContact CG2-CG 4.15Å; V71-F142 HydrophobicContact CG2-CZ 4.15Å; F74-F142 HydrophobicContact CB-CD2 4.49Å; F74-F142 HydrophobicContact CD1-CB 3.93Å; F74-F142 AromaticContact CD1-CD2 3.96Å; F74-F142 HydrophobicContact CD1-CD2 3.96Å; F74-F142 HydrophobicContact CD1-CG 4.4Å; F74-F142 HydrophobicContact CE1-CB 3.88Å; F74-F142 HydrophobicContact CE1-CD2 4.43Å; F74-F142 HydrophobicContact CG-CD2 4.19Å; I133-F142 HydrophobicContact CB-CE1 4.47Å; I133-F142 HydrophobicContact CB-CZ 4.2Å; I133-F142 HydrophobicContact CD1-CE1 3.83Å; I133-F142 HydrophobicContact CD1-CZ 4.32Å; I133-F142 HydrophobicContact CG2-CE1 3.8Å; I133-F142 HydrophobicContact CG2-CE2 4.21Å; I133-F142 HydrophobicContact CG2-CZ 3.59Å; L139-F142 HydrophobicContact CD2-CD2 4.28Å; F142-G144 PolarHBondContact O-N 2.92Å; F142-L211 HydrophobicContact CE2-CD2 4.16Å
143P81.1Confident78.8Confident65 Ų6568.4 Ų68.442%0.42236%0.364SS..PPolyproline II helixtrans-57132.1178.2-28.137.3000112.3I133I133-P143 HydrophobicContact CG2-CB 4.33Å; I133-P143 HydrophobicContact CG2-CG 3.87Å
144G79.1Confident78Confident43 Ų4371.8 Ų71.844%0.44339%0.389SS..PPolyproline II helixtrans-68.6140.8178.100000112.1F142 N183F142-G144 PolarHBondContact O-N 2.92Å; G144-N183 VanDerWaalsContact CA-OD1 3.23Å; G144-N183 WeakPolarHBondContact CA-OD1 3.34Å
145L81.9Confident76.9Confident10 Ų1070.5 Ų70.55%0.05238%0.381CS..PPolyproline II helixtrans-76.9143177-59.2-177.5000110.9L69 I84 I133 N183 I185L69-L145 HydrophobicContact CB-CD1 4Å; L69-L145 HydrophobicContact CD2-CD1 3.55Å; L69-L145 HydrophobicContact CG-CD1 3.7Å; I84-L145 HydrophobicContact CD1-CD1 4.01Å; I84-L145 HydrophobicContact CD1-CD2 4.18Å; I133-L145 HydrophobicContact CD1-CD2 3.57Å; L145-N183 WeakPolarHBondContact O-CA 3.43Å; L145-N183 PolarHBondContact O-N 3.25Å; L145-I185 HydrophobicContact CB-CG2 3.86Å; L145-I185 HydrophobicContact CD1-CG2 4.05Å
146R81.9Confident75.3Confident119 Ų11974.8 Ų74.845%0.44941%0.409SS..PPolyproline II helixtrans-99156.7-179.1-59.3-173.4-179.7178.50.1111.3H130 E174 V184H130-R146 PolarHBondContact CE1-O 3.48Å; R146-E174 HydrophobicContact CB-CB 3.87Å; R146-E174 HydrophobicContact CB-CG 4.16Å; R146-E174 WeakPolarHBondContact CD-OE2 3.47Å; R146-V184 CarbonylContact C-O 3.6Å
147K81Confident73.5Confident54 Ų5481.1 Ų81.124%0.23544%0.44CS..PPolyproline II helixtrans-73.6129.4176.8-168.7179-179.41790110.9E174 Y175 V184 T187K147-E174 WeakPolarHBondContact O-CA 3.3Å; K147-Y175 HydrophobicContact CB-CD2 4.25Å; K147-Y175 HydrophobicContact CD-CD2 4.39Å; K147-Y175 HydrophobicContact CG-CD2 4.37Å; K147-Y175 PolarHBondContact O-N 3.18Å; K147-V184 WeakPolarHBondContact CA-O 3.49Å; K147-V184 VanDerWaalsContact CB-O 3.27Å; K147-V184 WeakPolarHBondContact CB-O 3.42Å; K147-V184 HydrophobicContact CD-CG1 4.5Å; K147-V184 PolarHBondContact N-O 3.45Å; K147-V184 VanDerWaalsContact N-O 3.13Å; K147-T187 WeakPolarHBondContact CE-OG1 3.48Å; K147-T187 PolarHBondContact NZ-OG1 3.38Å
148A78.4Confident71.4Confident10 Ų1083.3 Ų83.38%0.08345%0.445CS..BIsolated β-bridgetrans-72.1137.9173.200000111.5W86 H128 A150 I185W86-A148 HydrophobicContact CH2-CB 4.21Å; W86-A148 HydrophobicContact CZ2-CB 3.97Å; H128-A148 HydrophobicContact CB-CB 4.05Å; A148-A150 HydrophobicContact CB-CB 4.37Å; A148-A150 PolarHBondContact O-N 3.43Å; A148-I185 PolarHBondContact N-O 3.1Å
149K72.5Confident69.6Low88 Ų8880.3 Ų80.338%0.38345%0.446SS..  trans-85.257167.8-65.7161.3174.9150.30110.4S172 D173 E174 Y175K149-S172 WeakPolarHBondContact O-CB 3.28Å; K149-S172 PolarHBondContact O-OG 3.41Å; K149-D173 WeakPolarHBondContact CB-O 3.39Å; K149-D173 HydrophobicContact CD-CB 3.76Å; K149-D173 WeakPolarHBondContact CD-O 3.36Å; K149-D173 VanDerWaalsContact CG-O 3.3Å; K149-D173 WeakPolarHBondContact CG-O 3.37Å; K149-D173 PolarHBondContact N-O 3.4Å; K149-E174 WeakPolarHBondContact CE-O 3.48Å; K149-E174 PolarHBondContact NZ-O 2.93Å; K149-Y175 HydrophobicContact CB-CE2 4.3Å; K149-Y175 HydrophobicContact CD-CD2 4.45Å; K149-Y175 HydrophobicContact CD-CE2 4.48Å; K149-Y175 HydrophobicContact CG-CD2 3.46Å; K149-Y175 VanDerWaalsContact CG-CD2 3.46Å; K149-Y175 HydrophobicContact CG-CE1 4.48Å; K149-Y175 HydrophobicContact CG-CE2 3.35Å; K149-Y175 HydrophobicContact CG-CG 4.11Å
150A70.2Confident67.3Low23 Ų2381.8 Ų81.819%0.1946%0.46CS..PPolyproline II helixtrans-101.7130.3178.100000110.4I126 A148 S172I126-A150 HydrophobicContact CB-CB 4.4Å; I126-A150 HydrophobicContact CD1-CB 4.28Å; I126-A150 HydrophobicContact CG1-CB 4.26Å; I126-A150 HydrophobicContact CG2-CB 3.41Å; I126-A150 VanDerWaalsContact CG2-CB 3.41Å; A148-A150 HydrophobicContact CB-CB 4.37Å; A148-A150 PolarHBondContact O-N 3.43Å; A150-S172 WeakPolarHBondContact CA-OG 3.21Å; A150-S172 WeakPolarHBondContact CB-OG 3.42Å
151E72.6Confident65.6Low167 Ų16782 Ų8278%0.7846%0.462SS*.PPolyproline II helixtrans-85.2145.4165.2-64.7-168.6161.600110.1R153E151-R153 PolarHBondContact O-N 3.29Å
152P76.8Confident63.7Low55 Ų5579.2 Ų79.236%0.35746%0.456SS..PPolyproline II helixtrans-63.7125.6179.5-17.330.1000111.2E124 I126 W189E124-P152 HydrophobicContact CB-CB 4.27Å; I126-P152 HydrophobicContact CD1-CG 4.35Å; P152-W189 HydrophobicContact CB-CD2 3.88Å; P152-W189 HydrophobicContact CB-CE3 4.49Å; P152-W189 HydrophobicContact CB-CG 4.1Å; P152-W189 HydrophobicContact CB-CZ2 4.03Å; P152-W189 HydrophobicContact CG-CB 3.94Å; P152-W189 HydrophobicContact CG-CD2 3.48Å; P152-W189 VanDerWaalsContact CG-CD2 3.48Å; P152-W189 HydrophobicContact CG-CE3 3.98Å; P152-W189 HydrophobicContact CG-CG 3.44Å; P152-W189 VanDerWaalsContact CG-CG 3.44Å
153R76.3Confident61.6Low122 Ų12282.1 Ų82.146%0.4648%0.477SS..EExtended strand (participates in β ladder)trans-96.9129.1177.6-62.8-177.8-176.9172.31.8109.9E124 C125 E151 N169E124-R153 CarbonylContact C-O 3.52Å; E124-R153 VanDerWaalsContact CA-O 3.28Å; E124-R153 WeakPolarHBondContact CA-O 3.45Å; C125-R153 PolarHBondContact N-O 2.93Å; C125-R153 PolarHBondContact O-N 3.36Å; E151-R153 PolarHBondContact O-N 3.29Å; R153-N169 PolarHBondContact NH2-O 3.43Å
154S69.7Low59.2Low90 Ų9081.3 Ų81.363%0.62948%0.48SS*.EExtended strand (participates in β ladder)trans-75.7130.7170.854.10000110.6P156S154-P156 WeakPolarHBondContact O-CD 3.22Å
155V62.6Low57.3Low25 Ų2589.2 Ų89.215%0.15250%0.503CS..PPolyproline II helixtrans-69122.5169.2176.60000109.2P119 G123P119-V155 WeakPolarHBondContact O-CG1 3.35Å; G123-V155 PolarHBondContact O-N 3.11Å
156P51.3Low55.1Low90 Ų9094.4 Ų94.458%0.58454%0.54SS*.PPolyproline II helixtrans-63.6138.8173.7-20.333.4000111.3S154 D158S154-P156 WeakPolarHBondContact O-CD 3.22Å; P156-D158 VanDerWaalsContact C-N 3.26Å; P156-D158 PolarHBondContact O-N 2.74Å
157L46.3Very low53Low159 Ų15993.3 Ų93.383%0.83254%0.543SS*.SBendtrans-72.9-17178-107.581.1000113.9P122P122-L157 HydrophobicContact CB-CD1 4.2Å
158D34.3Very low51.1Low131 Ų13196.1 Ų96.170%0.70157%0.567SS**SBendtrans-95.6143.7-169.1-150.3-10.1000111.8P156 S160P156-D158 VanDerWaalsContact C-N 3.26Å; P156-D158 PolarHBondContact O-N 2.74Å; D158-S160 PolarHBondContact O-N 2.94Å; D158-S160 PolarHBondContact O-OG 3.44Å
159G38.9Very low49.5Very low71 Ų71101.3 Ų101.373%0.73259%0.593SS**  trans-7115.2-170.900000115.7
160S30Very low48.2Very low82 Ų82100.7 Ų100.757%0.57359%0.588SS**SBendtrans-54138.1162.5490000110.2D158 G162D158-S160 PolarHBondContact O-N 2.94Å; D158-S160 PolarHBondContact O-OG 3.44Å; S160-G162 PolarHBondContact O-N 3.41Å
161E35.2Very low47.3Very low183 Ų183104.7 Ų104.786%0.85561%0.606SS**  trans-44.8123.4-178.3-60.4-179.9133.400111.4
162G37.8Very low46.5Very low56 Ų5697.6 Ų97.658%0.57758%0.575SS**SBendtrans-53.4147.8171.400000109.8S160 G164S160-G162 PolarHBondContact O-N 3.41Å; G162-G164 PolarHBondContact O-N 3.5Å
163P35Very low45.7Very low81 Ų81101 Ų10153%0.52659%0.589SS.*SBendtrans-45.3120.3-152.8-29.431.9000112.8K165 W170P163-K165 PolarHBondContact O-N 3.21Å; P163-W170 HydrophobicContact CB-CZ2 4.01Å; P163-W170 HydrophobicContact CG-CZ2 4.21Å
164G32.6Very low45.2Very low48 Ų4897.2 Ų97.250%0.49558%0.577SS.*  trans-50.5138.9-171.700000111.6G162 S166G162-G164 PolarHBondContact O-N 3.5Å; G164-S166 PolarHBondContact O-N 3Å
165K39Very low44.7Very low209 Ų20998.4 Ų98.491%0.90957%0.569SS**THydrogen-bonded Turntrans-47.8131.1174.2-65.8172.2179.5172.60109.1P163P163-K165 PolarHBondContact O-N 3.21Å
166S35.8Very low44.3Very low120 Ų120102.7 Ų102.784%0.83959%0.591SS**THydrogen-bonded Turntrans87.732.8177.476.10000119.9G164 P168G164-S166 PolarHBondContact O-N 3Å; S166-P168 WeakPolarHBondContact O-CD 3.42Å
167D37.3Very low44.4Very low96 Ų96102 Ų10251%0.51359%0.593SS.*  trans-79.4115154.3-110.3-27.2000111N169D167-N169 PolarHBondContact O-N 2.91Å; D167-N169 VanDerWaalsContact O-N 3.14Å
168P41Very low44.3Very low112 Ų112102.5 Ų102.573%0.72760%0.596SS**G310 helixtrans-68.2-12.1-179.427.5-34.2000113.7S166 W170S166-P168 WeakPolarHBondContact O-CD 3.42Å; P168-W170 PolarHBondContact O-N 3.16Å
169N43.6Very low45.1Very low120 Ų120100.4 Ų100.464%0.64261%0.605SS**G310 helixtrans-7714.3178-76.9-19.5000114.7R153 D167R153-N169 PolarHBondContact NH2-O 3.43Å; D167-N169 PolarHBondContact O-N 2.91Å; D167-N169 VanDerWaalsContact O-N 3.14Å
170W45.8Very low46Very low74 Ų7498.5 Ų98.528%0.2858%0.583SS.*G310 helixtrans-83.1-20.1176.2-90.860.6000114.3E127 P163 P168E127-W170 VanDerWaalsContact OE2-CZ3 3.25Å; E127-W170 WeakPolarHBondContact OE2-CZ3 3.47Å; P163-W170 HydrophobicContact CB-CZ2 4.01Å; P163-W170 HydrophobicContact CG-CZ2 4.21Å; P168-W170 PolarHBondContact O-N 3.16Å
171I51.8Low47.6Very low108 Ų108101.1 Ų101.155%0.55458%0.584SS**SBendtrans-100107.2176.2-56.6176.6000107.5
172S55.5Low49.3Very low18 Ų18100.1 Ų100.113%0.12658%0.579CS.*PPolyproline II helixtrans-75.2139.1176.1-69.30000110.6H128 K149 A150H128-S172 PolarHBondContact CE1-O 3.26Å; K149-S172 WeakPolarHBondContact O-CB 3.28Å; K149-S172 PolarHBondContact O-OG 3.41Å; A150-S172 WeakPolarHBondContact CA-OG 3.21Å; A150-S172 WeakPolarHBondContact CB-OG 3.42Å
173D59.3Low51.4Low125 Ų12598.2 Ų98.267%0.66856%0.556SS**PPolyproline II helixtrans-54.9144.2172.8-79.2-33.6000111.2K149K149-D173 WeakPolarHBondContact CB-O 3.39Å; K149-D173 HydrophobicContact CD-CB 3.76Å; K149-D173 WeakPolarHBondContact CD-O 3.36Å; K149-D173 VanDerWaalsContact CG-O 3.3Å; K149-D173 WeakPolarHBondContact CG-O 3.37Å; K149-D173 PolarHBondContact N-O 3.4Å
174E65.9Low53.8Low43 Ų4394.7 Ų94.720%0.20153%0.533CS..BIsolated β-bridgetrans-83.5151.2174-66-179.3167.500110.4H128 H130 R146 K147 K149H128-E174 IonicContact NE2-OE1 2.64Å; H128-E174 PolarHBondContact NE2-OE1 2.98Å; H130-E174 IonicContact CE1-OE1 3.91Å; H130-E174 IonicContact CG-OE1 3Å; H130-E174 IonicContact ND1-OE1 3.27Å; H130-E174 PolarHBondContact ND1-OE1 3.11Å; R146-E174 HydrophobicContact CB-CB 3.87Å; R146-E174 HydrophobicContact CB-CG 4.16Å; R146-E174 WeakPolarHBondContact CD-OE2 3.47Å; K147-E174 WeakPolarHBondContact O-CA 3.3Å; K149-E174 WeakPolarHBondContact CE-O 3.48Å; K149-E174 PolarHBondContact NZ-O 2.93Å
175Y59.6Low56.4Low116 Ų11692.4 Ų92.446%0.45551%0.509SS..PPolyproline II helixtrans-64.9143.1165.8-86.7-87.5000110.6K147 K149K147-Y175 HydrophobicContact CB-CD2 4.25Å; K147-Y175 HydrophobicContact CD-CD2 4.39Å; K147-Y175 HydrophobicContact CG-CD2 4.37Å; K147-Y175 PolarHBondContact O-N 3.18Å; K149-Y175 HydrophobicContact CB-CE2 4.3Å; K149-Y175 HydrophobicContact CD-CD2 4.45Å; K149-Y175 HydrophobicContact CD-CE2 4.48Å; K149-Y175 HydrophobicContact CG-CD2 3.46Å; K149-Y175 VanDerWaalsContact CG-CD2 3.46Å; K149-Y175 HydrophobicContact CG-CE1 4.48Å; K149-Y175 HydrophobicContact CG-CE2 3.35Å; K149-Y175 HydrophobicContact CG-CG 4.11Å
176N55.3Low58.7Low115 Ų11582.6 Ų82.662%0.61547%0.467SS*.PPolyproline II helixtrans-65.9156.1171.9-71.8-19.3000110D178N176-D178 PolarHBondContact O-N 3.31Å
177A52.4Low61.2Low76 Ų7678.9 Ų78.963%0.62844%0.439SS*.THydrogen-bonded Turntrans-62.2-30.5-177.100000113G179A177-G179 PolarHBondContact O-N 3.4Å
178D45.4Very low63.7Low169 Ų16974.4 Ų74.490%0.90442%0.416SS*.THydrogen-bonded Turntrans-68.793.6172.6-75.4-42.4000111.4N176N176-D178 PolarHBondContact O-N 3.31Å
179G49.8Very low66Low86 Ų8671.1 Ų71.189%0.88739%0.389SS*.THydrogen-bonded Turntrans114.2-9.1168.200000116A177A177-G179 PolarHBondContact O-N 3.4Å
180A58.2Low68.2Low32 Ų3271.2 Ų71.226%0.26438%0.38SS..SBendtrans-89.3135.8174.300000111.6E182A180-E182 PolarHBondContact O-N 3.34Å
181K63Low70.3Confident136 Ų13671.6 Ų71.659%0.59139%0.388SS*.PPolyproline II helixtrans-62.1126.2168.8-69.3174.9-179.6168.30109.3D66 V184D66-K181 IonicContact OD1-NZ 2.92Å; D66-K181 IonicContact OD2-NZ 3.3Å; D66-K181 PolarHBondContact OD2-NZ 3.39Å; K181-V184 HydrophobicContact CB-CB 4.35Å; K181-V184 HydrophobicContact CB-CG2 3.57Å; K181-V184 HydrophobicContact CD-CG2 4.29Å; K181-V184 PolarHBondContact O-N 3.46Å
182E71.7Confident72Confident162 Ų16266.4 Ų66.476%0.75736%0.361SS*.THydrogen-bonded Turntrans-57.1141.6-178.9-62.1-172.2160.100112.7A180 V184A180-E182 PolarHBondContact O-N 3.34Å; E182-V184 PolarHBondContact O-N 3.05Å; E182-V184 VanDerWaalsContact O-N 3.13Å
183N81.3Confident73.5Confident16 Ų1665.6 Ų65.69%0.08636%0.355CS..THydrogen-bonded Turntrans65.41.7177.3-50.6-82.8000115.6V68 L69 K70 G144 L145 I185V68-N183 CarbonylContact C-O 3.6Å; V68-N183 VanDerWaalsContact CA-O 3.31Å; V68-N183 WeakPolarHBondContact CA-O 3.45Å; V68-N183 HydrophobicContact CG1-CB 3.64Å; V68-N183 WeakPolarHBondContact CG1-O 3.49Å; L69-N183 PolarHBondContact N-O 3.11Å; K70-N183 HydrophobicContact CB-CB 4.17Å; G144-N183 VanDerWaalsContact CA-OD1 3.23Å; G144-N183 WeakPolarHBondContact CA-OD1 3.34Å; L145-N183 WeakPolarHBondContact O-CA 3.43Å; L145-N183 PolarHBondContact O-N 3.25Å; N183-I185 PolarHBondContact O-N 3.24Å
184V85.6Confident74.9Confident7 Ų759.7 Ų59.74%0.04232%0.324CS..EExtended strand (participates in β ladder)trans-76.4114.3171.5179.10000108.9D66 V67 V68 R146 K147 K181 E182 A186 T187D66-V184 HydrophobicContact CB-CG1 4.29Å; D66-V184 HydrophobicContact CB-CG2 4.3Å; V67-V184 WeakPolarHBondContact O-CA 3.42Å; V68-V184 HydrophobicContact CG2-CG2 4.25Å; R146-V184 CarbonylContact C-O 3.6Å; K147-V184 WeakPolarHBondContact CA-O 3.49Å; K147-V184 VanDerWaalsContact CB-O 3.27Å; K147-V184 WeakPolarHBondContact CB-O 3.42Å; K147-V184 HydrophobicContact CD-CG1 4.5Å; K147-V184 PolarHBondContact N-O 3.45Å; K147-V184 VanDerWaalsContact N-O 3.13Å; K181-V184 HydrophobicContact CB-CB 4.35Å; K181-V184 HydrophobicContact CB-CG2 3.57Å; K181-V184 HydrophobicContact CD-CG2 4.29Å; K181-V184 PolarHBondContact O-N 3.46Å; E182-V184 PolarHBondContact O-N 3.05Å; E182-V184 VanDerWaalsContact O-N 3.13Å; V184-A186 WeakPolarHBondContact CG1-O 3.46Å; V184-T187 HydrophobicContact CG1-CG2 4.32Å
185I86.6Confident75.9Confident0 Ų057.7 Ų57.70%031%0.314CS..EExtended strand (participates in β ladder)trans-86.4-38178.951.5160.8000112.2V67 L69 W86 L145 A148 N183 L196V67-I185 HydrophobicContact CB-CG1 4.32Å; V67-I185 HydrophobicContact CG1-CD1 4.04Å; V67-I185 HydrophobicContact CG1-CG1 4.01Å; V67-I185 VanDerWaalsContact O-CG1 3.3Å; V67-I185 WeakPolarHBondContact O-CG1 3.38Å; V67-I185 PolarHBondContact O-N 3.46Å; L69-I185 HydrophobicContact CB-CD1 3.88Å; L69-I185 HydrophobicContact CB-CG1 4Å; L69-I185 HydrophobicContact CB-CG2 3.79Å; L69-I185 HydrophobicContact CD2-CD1 4.02Å; L69-I185 HydrophobicContact CD2-CG2 4.29Å; W86-I185 HydrophobicContact CD2-CD1 3.9Å; W86-I185 HydrophobicContact CE3-CD1 4.36Å; W86-I185 HydrophobicContact CG-CD1 4.07Å; W86-I185 HydrophobicContact CZ2-CB 3.83Å; W86-I185 HydrophobicContact CZ2-CD1 4.47Å; W86-I185 WeakPolarHBondContact CZ2-O 3.49Å; L145-I185 HydrophobicContact CB-CG2 3.86Å; L145-I185 HydrophobicContact CD1-CG2 4.05Å; A148-I185 PolarHBondContact N-O 3.1Å; N183-I185 PolarHBondContact O-N 3.24Å; I185-L196 HydrophobicContact CD1-CD1 4.24Å
186A87.3Confident77.2Confident4 Ų452.2 Ų52.23%0.03329%0.293CS..EExtended strand (participates in β ladder)trans-149.7163.5-174.900000111.8V67 W86 L88 V184V67-A186 HydrophobicContact CB-CB 4.45Å; V67-A186 PolarHBondContact N-O 3.17Å; W86-A186 HydrophobicContact CH2-CB 3.75Å; W86-A186 HydrophobicContact CZ3-CB 4.03Å; L88-A186 HydrophobicContact CD2-CB 3.72Å; V184-A186 WeakPolarHBondContact CG1-O 3.46Å
187T89.3Confident78.7Confident41 Ų4146.7 Ų46.725%0.25226%0.264SS..EExtended strand (participates in β ladder)trans-131.4134170.247.70000109.9T65 D66 K147 V184T65-T187 WeakPolarHBondContact O-CA 3.41Å; D66-T187 VanDerWaalsContact OD1-CG2 3.23Å; D66-T187 WeakPolarHBondContact OD1-CG2 3.41Å; K147-T187 WeakPolarHBondContact CE-OG1 3.48Å; K147-T187 PolarHBondContact NZ-OG1 3.38Å; V184-T187 HydrophobicContact CG1-CG2 4.32Å
188T89.9Confident80.4Confident3 Ų343.2 Ų43.22%0.01823%0.234CC..  trans-66.6142.7-179.8580000112M61 F62 E64 T65 Y194M61-T188 HydrophobicContact CB-CG2 4Å; M61-T188 HydrophobicContact CE-CG2 3.63Å; M61-T188 HydrophobicContact SD-CG2 3.86Å; F62-T188 PolarHBondContact O-OG1 2.99Å; E64-T188 PolarHBondContact N-O 3.38Å; E64-T188 PolarHBondContact N-OG1 2.94Å; T65-T188 WeakPolarHBondContact CB-OG1 3.46Å; T65-T188 PolarHBondContact N-OG1 3.4Å; T65-T188 PolarHBondContact O-N 2.95Å; T188-Y194 HydrophobicContact CG2-CD1 4.39Å; T188-Y194 HydrophobicContact CG2-CD2 3.93Å; T188-Y194 HydrophobicContact CG2-CE1 4.18Å; T188-Y194 HydrophobicContact CG2-CE2 3.7Å; T188-Y194 HydrophobicContact CG2-CG 4.28Å
189W89.3Confident82.4Confident42 Ų4239.2 Ų39.216%0.15921%0.209CC..  trans-107.7-18.8-173.85595.4000113.5K63 L88 E124 I126 P152 Y194K63-W189 WeakPolarHBondContact CD-O 3.43Å; K63-W189 WeakPolarHBondContact CE-O 3.44Å; K63-W189 WeakPolarHBondContact CG-O 3.28Å; L88-W189 HydrophobicContact CD2-CH2 4.48Å; L88-W189 HydrophobicContact CD2-CZ3 3.91Å; L88-W189 HydrophobicContact CG-CH2 4.25Å; L88-W189 HydrophobicContact CG-CZ3 4.18Å; E124-W189 HydrophobicContact CB-CZ2 3.94Å; E124-W189 WeakPolarHBondContact O-CZ2 3.26Å; E124-W189 PolarHBondContact OE2-NE1 3.26Å; I126-W189 HydrophobicContact CB-CH2 4.49Å; I126-W189 HydrophobicContact CB-CZ3 4.44Å; I126-W189 HydrophobicContact CD1-CE3 3.88Å; I126-W189 HydrophobicContact CD1-CH2 4.2Å; I126-W189 HydrophobicContact CD1-CZ3 3.51Å; I126-W189 HydrophobicContact CG1-CH2 4Å; I126-W189 HydrophobicContact CG1-CZ3 3.83Å; P152-W189 HydrophobicContact CB-CD2 3.88Å; P152-W189 HydrophobicContact CB-CE3 4.49Å; P152-W189 HydrophobicContact CB-CG 4.1Å; P152-W189 HydrophobicContact CB-CZ2 4.03Å; P152-W189 HydrophobicContact CG-CB 3.94Å; P152-W189 HydrophobicContact CG-CD2 3.48Å; P152-W189 VanDerWaalsContact CG-CD2 3.48Å; P152-W189 HydrophobicContact CG-CE3 3.98Å; P152-W189 HydrophobicContact CG-CG 3.44Å; P152-W189 VanDerWaalsContact CG-CG 3.44Å; W189-Y194 HydrophobicContact CD2-CE1 4.26Å; W189-Y194 HydrophobicContact CE3-CE1 4.18Å; W189-Y194 HydrophobicContact CH2-CD1 4.45Å; W189-Y194 AromaticContact CH2-CE1 3.7Å; W189-Y194 HydrophobicContact CH2-CE1 3.7Å; W189-Y194 AromaticContact CZ2-CE1 3.74Å; W189-Y194 HydrophobicContact CZ2-CE1 3.74Å; W189-Y194 AromaticContact CZ3-CE1 3.91Å; W189-Y194 HydrophobicContact CZ3-CE1 3.91Å; W189-Y194 PolarHBondContact N-OH 3.39Å
190R88.8Confident84.2Confident123 Ų12336.1 Ų36.146%0.46417%0.173SC..SBendtrans-130169.2174.6-72.9-178.3-166.9-91.55.8111.1K63 Y90 E124 Y194K63-R190 WeakPolarHBondContact CA-O 3.22Å; K63-R190 PolarHBondContact N-O 2.91Å; Y90-R190 HydrophobicContact CD2-CB 4.41Å; Y90-R190 HydrophobicContact CE2-CB 4.25Å; E124-R190 VanDerWaalsContact CD-NE 3.29Å; E124-R190 IonicContact OE1-CZ 2.68Å; E124-R190 VanDerWaalsContact OE1-CZ 3.29Å; E124-R190 IonicContact OE1-NE 2.65Å; E124-R190 PolarHBondContact OE1-NE 3.45Å; E124-R190 IonicContact OE1-NH2 3.57Å; E124-R190 PolarHBondContact OE1-NH2 2.96Å; E124-R190 WeakPolarHBondContact OE2-CD 3.46Å; E124-R190 IonicContact OE2-CZ 3.38Å; E124-R190 IonicContact OE2-NE 3.63Å; E124-R190 PolarHBondContact OE2-NE 3.31Å; E124-R190 IonicContact OE2-NH2 3.18Å; R190-Y194 PolarHBondContact N-OH 2.93Å; R190-Y194 WeakPolarHBondContact O-CE2 3.39Å; R190-Y194 PolarHBondContact O-OH 3.18Å
191N89.4Confident85.5Confident81 Ų8137.3 Ų37.343%0.43317%0.174SC..SBendtrans-85.7132.7166.7-74.6-17.2000109K63 I226 W441K63-N191 WeakPolarHBondContact CB-OD1 3.36Å; K63-N191 PolarHBondContact N-OD1 3.35Å; N191-I226 HydrophobicContact CB-CD1 3.65Å; N191-W441 HydrophobicContact CB-CH2 4.47Å
192G87.9Confident86.7Confident0 Ų031.7 Ų31.70%015%0.152CC..EExtended strand (participates in β ladder)trans141.7-164.6168.800000114.8A60 M61 Y194A60-G192 CarbonylContact C-O 3.53Å; A60-G192 WeakPolarHBondContact CA-O 3.35Å; M61-G192 PolarHBondContact N-O 3.34Å; M61-G192 PolarHBondContact O-N 2.93Å; G192-Y194 VanDerWaalsContact O-CD2 3.3Å; G192-Y194 WeakPolarHBondContact O-CD2 3.38Å
193P87.8Confident87.3Confident1 Ų129.6 Ų29.61%0.00615%0.146CC..EExtended strand (participates in β ladder)trans-74.6127.6-175.228.9-31.2000111.9H91 Y94 Y97H91-P193 HydrophobicContact CB-CG 4.45Å; H91-P193 PolarHBondContact N-O 3.45Å; H91-P193 VanDerWaalsContact O-CG 3.26Å; H91-P193 WeakPolarHBondContact O-CG 3.23Å; Y94-P193 HydrophobicContact CD2-CB 4.48Å; Y94-P193 HydrophobicContact CD2-CG 4.33Å; Y97-P193 HydrophobicContact CD1-CB 4.2Å; Y97-P193 HydrophobicContact CD2-CB 3.53Å; Y97-P193 HydrophobicContact CE1-CB 4.33Å; Y97-P193 HydrophobicContact CE2-CB 3.65Å; Y97-P193 HydrophobicContact CG-CB 3.79Å
194Y87.8Confident87.4Confident1 Ų132.7 Ų32.70%0.00416%0.161CC..EExtended strand (participates in β ladder)trans-119.6141.7177.5-81.1-88.2000111.1K59 M61 L88 K89 Y90 T188 W189 R190 G192K59-Y194 PolarHBondContact N-O 2.97Å; K59-Y194 PolarHBondContact O-N 2.97Å; M61-Y194 HydrophobicContact CB-CD2 3.98Å; M61-Y194 HydrophobicContact CB-CE2 4.49Å; M61-Y194 HydrophobicContact CE-CD1 4.46Å; M61-Y194 HydrophobicContact CE-CD2 4.01Å; M61-Y194 HydrophobicContact CE-CG 3.72Å; L88-Y194 HydrophobicContact CD1-CD1 3.79Å; L88-Y194 HydrophobicContact CD1-CG 4.33Å; L88-Y194 HydrophobicContact CD2-CD1 4.5Å; L88-Y194 HydrophobicContact CG-CD1 3.97Å; L88-Y194 HydrophobicContact CG-CE1 4.45Å; K89-Y194 CarbonylContact O-C 3.55Å; K89-Y194 WeakPolarHBondContact O-CA 3.45Å; Y90-Y194 HydrophobicContact CD2-CD2 4.48Å; Y90-Y194 HydrophobicContact CD2-CE1 4.37Å; Y90-Y194 HydrophobicContact CD2-CE2 4.02Å; Y90-Y194 AromaticContact CD2-CZ 3.95Å; Y90-Y194 HydrophobicContact CG-CE1 4.47Å; T188-Y194 HydrophobicContact CG2-CD1 4.39Å; T188-Y194 HydrophobicContact CG2-CD2 3.93Å; T188-Y194 HydrophobicContact CG2-CE1 4.18Å; T188-Y194 HydrophobicContact CG2-CE2 3.7Å; T188-Y194 HydrophobicContact CG2-CG 4.28Å; W189-Y194 HydrophobicContact CD2-CE1 4.26Å; W189-Y194 HydrophobicContact CE3-CE1 4.18Å; W189-Y194 HydrophobicContact CH2-CD1 4.45Å; W189-Y194 AromaticContact CH2-CE1 3.7Å; W189-Y194 HydrophobicContact CH2-CE1 3.7Å; W189-Y194 AromaticContact CZ2-CE1 3.74Å; W189-Y194 HydrophobicContact CZ2-CE1 3.74Å; W189-Y194 AromaticContact CZ3-CE1 3.91Å; W189-Y194 HydrophobicContact CZ3-CE1 3.91Å; W189-Y194 PolarHBondContact N-OH 3.39Å; R190-Y194 PolarHBondContact N-OH 2.93Å; R190-Y194 WeakPolarHBondContact O-CE2 3.39Å; R190-Y194 PolarHBondContact O-OH 3.18Å; G192-Y194 VanDerWaalsContact O-CD2 3.3Å; G192-Y194 WeakPolarHBondContact O-CD2 3.38Å
195L87.1Confident86.9Confident1 Ų138.2 Ų38.21%0.00519%0.19CC..EExtended strand (participates in β ladder)trans-111.1124170.8-174.576.7000109.3I56 L88 K89 I100 P117 V197I56-L195 HydrophobicContact CG2-CD1 3.76Å; L88-L195 CarbonylContact C-O 3.58Å; L88-L195 WeakPolarHBondContact CA-O 3.37Å; K89-L195 PolarHBondContact N-O 3.48Å; K89-L195 PolarHBondContact O-N 3.21Å; I100-L195 HydrophobicContact CD1-CD1 3.99Å; I100-L195 HydrophobicContact CD1-CD2 4.16Å; I100-L195 HydrophobicContact CG2-CD1 4.22Å; I100-L195 HydrophobicContact CG2-CD2 4.31Å; P117-L195 HydrophobicContact CG-CD2 3.69Å; L195-V197 HydrophobicContact CD2-CG2 3.87Å; L195-V197 HydrophobicContact CG-CG2 4.11Å
196L88.2Confident86.3Confident0 Ų047 Ų470%023%0.232CC..EExtended strand (participates in β ladder)trans-107121.2169.217970.2000109.1L57 V67 L87 L88 I185 V198 V215 M217L57-L196 HydrophobicContact CB-CB 4.41Å; L57-L196 HydrophobicContact CD1-CD2 4.47Å; L57-L196 PolarHBondContact N-O 2.84Å; L57-L196 PolarHBondContact O-N 3.44Å; V67-L196 HydrophobicContact CG1-CD2 3.97Å; L87-L196 CarbonylContact O-C 3.52Å; L87-L196 WeakPolarHBondContact O-CA 3.29Å; L88-L196 HydrophobicContact CB-CD1 4.34Å; L88-L196 HydrophobicContact CD1-CB 4.26Å; L88-L196 HydrophobicContact CD1-CD1 4.41Å; I185-L196 HydrophobicContact CD1-CD1 4.24Å; L196-V198 HydrophobicContact CD1-CG2 4.19Å; L196-V198 HydrophobicContact CD2-CG2 4.06Å; L196-V198 HydrophobicContact CG-CG2 3.88Å; L196-V215 HydrophobicContact CD2-CG1 3.87Å; L196-M217 HydrophobicContact CB-CE 3.73Å; L196-M217 HydrophobicContact CD2-CE 3.65Å; L196-M217 HydrophobicContact CG-CE 4.34Å
197V86.8Confident85.9Confident0 Ų047.2 Ų47.20%023%0.233CC..EExtended strand (participates in β ladder)trans-111.2127.5171.3-171.90000108.4P54 I55 W86 L87 L115 L195P54-V197 HydrophobicContact CB-CG1 4.17Å; I55-V197 CarbonylContact O-C 3.57Å; I55-V197 VanDerWaalsContact O-CA 3.28Å; I55-V197 WeakPolarHBondContact O-CA 3.5Å; W86-V197 CarbonylContact C-O 3.54Å; W86-V197 WeakPolarHBondContact CA-O 3.45Å; L87-V197 HydrophobicContact CB-CB 4.45Å; L87-V197 PolarHBondContact N-O 3.37Å; L87-V197 PolarHBondContact O-N 3.27Å; L115-V197 HydrophobicContact CB-CG1 4.36Å; L115-V197 HydrophobicContact CD2-CB 4.4Å; L115-V197 HydrophobicContact CD2-CG1 4.1Å; L115-V197 HydrophobicContact CG-CG1 4.36Å; L195-V197 HydrophobicContact CD2-CG2 3.87Å; L195-V197 HydrophobicContact CG-CG2 4.11Å
198V87.4Confident85.5Confident3 Ų349.2 Ų49.22%0.01825%0.249CC..EExtended strand (participates in β ladder)trans-126.3124.4177.9-171.40000110.2P54 I55 L69 I84 W86 L196P54-V198 WeakPolarHBondContact CA-O 3.47Å; I55-V198 HydrophobicContact CB-CB 4.2Å; I55-V198 PolarHBondContact N-O 3.18Å; I55-V198 PolarHBondContact O-N 2.95Å; L69-V198 HydrophobicContact CD2-CG1 4.08Å; L69-V198 HydrophobicContact CD2-CG2 4.47Å; I84-V198 HydrophobicContact CG2-CG1 3.94Å; W86-V198 HydrophobicContact CB-CB 4.48Å; W86-V198 HydrophobicContact CB-CG1 4.39Å; W86-V198 HydrophobicContact CB-CG2 4.07Å; L196-V198 HydrophobicContact CD1-CG2 4.19Å; L196-V198 HydrophobicContact CD2-CG2 4.06Å; L196-V198 HydrophobicContact CG-CG2 3.88Å
199K87.3Confident85.4Confident85 Ų8549.8 Ų49.837%0.3725%0.251SS..EExtended strand (participates in β ladder)trans-119.4122176.4-170.2175.7-178.8177.50109.7P54 H85 L115 I201P54-K199 HydrophobicContact CB-CB 4.32Å; H85-K199 PolarHBondContact N-O 3.4Å; H85-K199 PolarHBondContact O-N 3.1Å; L115-K199 HydrophobicContact CD2-CB 4.08Å; K199-I201 HydrophobicContact CD-CD1 4.38Å; K199-I201 HydrophobicContact CD-CG1 4.27Å; K199-I201 HydrophobicContact CG-CG1 4.02Å
200V87.3Confident85.3Confident21 Ų2150.9 Ų50.913%0.12726%0.259CS..EExtended strand (participates in β ladder)trans-93.1121.4172-175.10000108.1V48 F82 W209 L211V48-V200 HydrophobicContact CG1-CB 4.22Å; V48-V200 HydrophobicContact CG1-CG2 4.1Å; F82-V200 HydrophobicContact CB-CG1 4.22Å; F82-V200 HydrophobicContact CD1-CG1 4.09Å; F82-V200 HydrophobicContact CG-CG1 4.39Å; V200-W209 HydrophobicContact CB-CH2 4.24Å; V200-W209 HydrophobicContact CG1-CH2 3.97Å; V200-W209 HydrophobicContact CG1-CZ3 4.4Å; V200-L211 HydrophobicContact CG1-CD1 4Å
201I86.1Confident85.3Confident57 Ų5745.1 Ų45.129%0.29224%0.238SC..EExtended strand (participates in β ladder)trans-113.2113-176.5-56174.8000108.2F82 T83 H85 K199F82-I201 WeakPolarHBondContact CA-O 3.47Å; T83-I201 PolarHBondContact N-O 3.28Å; T83-I201 PolarHBondContact O-N 3.41Å; H85-I201 HydrophobicContact CB-CD1 4.3Å; K199-I201 HydrophobicContact CD-CD1 4.38Å; K199-I201 HydrophobicContact CD-CG1 4.27Å; K199-I201 HydrophobicContact CG-CG1 4.02Å
202P87.1Confident85.3Confident18 Ų1842.2 Ų42.212%0.11722%0.223CC..EExtended strand (participates in β ladder)trans-75.8151.9173.632.5-34.5000111.6V80 F82 I204 W209V80-P202 HydrophobicContact CG1-CB 4.29Å; F82-P202 HydrophobicContact CD1-CB 3.95Å; F82-P202 HydrophobicContact CE1-CB 3.88Å; P202-I204 VanDerWaalsContact C-N 3.33Å; P202-W209 HydrophobicContact CB-CZ2 4.48Å; P202-W209 HydrophobicContact CG-CZ2 4.31Å
203D85.4Confident85.4Confident118 Ų11842.5 Ų42.563%0.63123%0.225SC*.SBendtrans-75.2-25168.8-165.935.7000111.5K81K81-D203 HydrophobicContact CB-CB 3.79Å; K81-D203 WeakPolarHBondContact O-CB 3.3Å; K81-D203 PolarHBondContact O-N 2.83Å
204I82Confident85.6Confident81 Ų8143.9 Ų43.942%0.41523%0.232SC..SBendtrans-123104.3178.9-54.9174.3000109.2P202 E206 A207P202-I204 VanDerWaalsContact C-N 3.33Å; I204-E206 PolarHBondContact O-N 3.04Å; I204-A207 HydrophobicContact CB-CB 4.26Å; I204-A207 HydrophobicContact CG2-CB 4.12Å; I204-A207 PolarHBondContact O-N 3.41Å
205N75.4Confident85.7Confident122 Ų12243.9 Ų43.965%0.65223%0.232SC*.THydrogen-bonded Turntrans-66.6-17.3-175.9-68.4-25.4000114.9N50N50-N205 PolarHBondContact ND2-O 3.17Å
206E75.6Confident85.9Confident186 Ų18644.7 Ų44.787%0.86924%0.237SC*.THydrogen-bonded Turntrans-101.90.3-178.2-64.2-177.7-178.700113.6I204I204-E206 PolarHBondContact O-N 3.04Å
207A77.3Confident86.1Confident7 Ų744.8 Ų44.86%0.05824%0.238CC..  trans-74.4136.9179.500000111.3N50 V80 I204N50-A207 PolarHBondContact ND2-O 3.17Å; V80-A207 HydrophobicContact CG2-CB 3.49Å; V80-A207 VanDerWaalsContact CG2-CB 3.49Å; I204-A207 HydrophobicContact CB-CB 4.26Å; I204-A207 HydrophobicContact CG2-CB 4.12Å; I204-A207 PolarHBondContact O-N 3.41Å
208S82.2Confident86.1Confident83 Ų8351.1 Ų51.158%0.5826%0.262SS*.  trans-77.3127.1164.949.30000109.4P77P77-S208 VanDerWaalsContact CD-O 3.22Å; P77-S208 WeakPolarHBondContact CD-O 3.44Å
209W86.9Confident86.1Confident16 Ų1651.7 Ų51.76%0.06127%0.268CS..  trans-155.2156.5176.456.3-93000110.2V48 N50 S75 F82 V200 P202 L211V48-W209 HydrophobicContact CB-CZ3 4.19Å; V48-W209 HydrophobicContact CG1-CH2 3.8Å; V48-W209 HydrophobicContact CG1-CZ3 3.82Å; V48-W209 WeakPolarHBondContact O-CZ3 3.37Å; N50-W209 HydrophobicContact CB-CZ2 4.39Å; S75-W209 VanDerWaalsContact O-CA 3.32Å; S75-W209 WeakPolarHBondContact O-CA 3.38Å; F82-W209 HydrophobicContact CE1-CB 4.46Å; F82-W209 AromaticContact CE1-CD1 3.74Å; F82-W209 AromaticContact CE1-CD2 3.48Å; F82-W209 HydrophobicContact CE1-CD2 3.48Å; F82-W209 VanDerWaalsContact CE1-CD2 3.48Å; F82-W209 AromaticContact CE1-CE2 3.48Å; F82-W209 VanDerWaalsContact CE1-CE2 3.48Å; F82-W209 HydrophobicContact CE1-CE3 4.05Å; F82-W209 AromaticContact CE1-CG 3.67Å; F82-W209 HydrophobicContact CE1-CG 3.67Å; F82-W209 HydrophobicContact CE1-CZ2 4.02Å; F82-W209 AromaticContact CE1-NE1 3.65Å; F82-W209 HydrophobicContact CZ-CB 3.81Å; F82-W209 AromaticContact CZ-CD1 3.88Å; F82-W209 AromaticContact CZ-CD2 3.67Å; F82-W209 HydrophobicContact CZ-CD2 3.67Å; F82-W209 HydrophobicContact CZ-CE3 4.16Å; F82-W209 AromaticContact CZ-CG 3.5Å; F82-W209 HydrophobicContact CZ-CG 3.5Å; V200-W209 HydrophobicContact CB-CH2 4.24Å; V200-W209 HydrophobicContact CG1-CH2 3.97Å; V200-W209 HydrophobicContact CG1-CZ3 4.4Å; P202-W209 HydrophobicContact CB-CZ2 4.48Å; P202-W209 HydrophobicContact CG-CZ2 4.31Å; W209-L211 HydrophobicContact CE3-CB 4.34Å; W209-L211 HydrophobicContact CE3-CD1 3.88Å; W209-L211 HydrophobicContact CE3-CG 3.78Å; W209-L211 HydrophobicContact CZ3-CB 4.18Å; W209-L211 HydrophobicContact CZ3-CD1 3.73Å; W209-L211 HydrophobicContact CZ3-CG 3.93Å
210N88.4Confident86.1Confident64 Ų6455.1 Ų55.134%0.34228%0.283SS..EExtended strand (participates in β ladder)trans-139.9126.5175.2-178.1-14.4000109V48 V49 F74 S75V48-N210 WeakPolarHBondContact O-CA 3.42Å; V49-N210 HydrophobicContact CG1-CB 4.28Å; F74-N210 CarbonylContact C-O 3.59Å; F74-N210 WeakPolarHBondContact CA-O 3.41Å; S75-N210 PolarHBondContact N-O 3.49Å; S75-N210 PolarHBondContact O-N 2.98Å
211L87.9Confident85.9Confident2 Ų258.5 Ų58.51%0.0130%0.297CS..EExtended strand (participates in β ladder)trans-124117.7178-66.2172.6000109.1V48 V71 F74 F82 F142 V200 W209V48-L211 HydrophobicContact CB-CB 4.46Å; V48-L211 WeakPolarHBondContact CB-O 3.05Å; V48-L211 PolarHBondContact N-O 3.45Å; V48-L211 PolarHBondContact O-N 3.11Å; V71-L211 HydrophobicContact CG1-CD2 4.16Å; F74-L211 HydrophobicContact CB-CD2 3.46Å; F74-L211 VanDerWaalsContact CB-CD2 3.46Å; F82-L211 HydrophobicContact CD1-CD1 4.43Å; F82-L211 HydrophobicContact CD2-CD1 4.11Å; F82-L211 HydrophobicContact CE2-CD1 4.19Å; F82-L211 HydrophobicContact CG-CD1 4.23Å; F82-L211 HydrophobicContact CZ-CD1 4.41Å; F142-L211 HydrophobicContact CE2-CD2 4.16Å; V200-L211 HydrophobicContact CG1-CD1 4Å; W209-L211 HydrophobicContact CE3-CB 4.34Å; W209-L211 HydrophobicContact CE3-CD1 3.88Å; W209-L211 HydrophobicContact CE3-CG 3.78Å; W209-L211 HydrophobicContact CZ3-CB 4.18Å; W209-L211 HydrophobicContact CZ3-CD1 3.73Å; W209-L211 HydrophobicContact CZ3-CG 3.93Å
212T89.6Confident86Confident21 Ų2156.3 Ų56.313%0.12929%0.289CS..EExtended strand (participates in β ladder)trans-91.4109.4171.9-40.80000109.7K45 I46 V72 S73K45-T212 HydrophobicContact CD-CG2 4.5Å; K45-T212 HydrophobicContact CG-CG2 3.81Å; I46-T212 CarbonylContact O-C 3.58Å; I46-T212 WeakPolarHBondContact O-CA 3.45Å; V72-T212 PolarHBondContact N-O 2.97Å; S73-T212 PolarHBondContact O-N 3.41Å; S73-T212 WeakPolarHBondContact OG-CB 3.39Å; S73-T212 PolarHBondContact OG-OG1 3.33Å
213V89.9Confident86.1Confident5 Ų557 Ų573%0.0329%0.289CS..EExtended strand (participates in β ladder)trans-96.2132.8-178.3-177.80000109.3K45 I46 V48 I55 L69 V215K45-V213 WeakPolarHBondContact CA-O 3.48Å; I46-V213 PolarHBondContact N-O 3.5Å; I46-V213 PolarHBondContact O-N 2.87Å; V48-V213 HydrophobicContact CG2-CB 4.47Å; V48-V213 HydrophobicContact CG2-CG2 3.8Å; I55-V213 HydrophobicContact CD1-CB 4.37Å; I55-V213 HydrophobicContact CD1-CG1 4.48Å; L69-V213 HydrophobicContact CD1-CG1 3.33Å; L69-V213 HydrophobicContact CG-CG1 4.33Å; V213-V215 HydrophobicContact CG1-CG2 4.19Å
214N91.4Very high86.2Confident31 Ų3151.7 Ų51.717%0.16626%0.261CS..EExtended strand (participates in β ladder)trans-111.1114.3173.7-174.672000109.2L43 W44 K70 V72 V216L43-N214 WeakPolarHBondContact CD1-OD1 3.35Å; W44-N214 CarbonylContact O-C 3.48Å; W44-N214 VanDerWaalsContact O-CA 3.27Å; W44-N214 WeakPolarHBondContact O-CA 3.42Å; W44-N214 PolarHBondContact O-OD1 3.36Å; K70-N214 PolarHBondContact N-O 3.33Å; K70-N214 PolarHBondContact O-N 3.01Å; V72-N214 HydrophobicContact CG2-CB 3.42Å; V72-N214 VanDerWaalsContact CG2-CB 3.42Å; N214-V216 VanDerWaalsContact ND2-CG2 3.32Å; N214-V216 WeakPolarHBondContact ND2-CG2 3.42Å
215V91.3Very high86.5Confident0 Ų047.8 Ų47.80%024%0.241CC..EExtended strand (participates in β ladder)trans-100.5132.3176.2-173.60000108.7L43 W44 L57 V68 L69 L196 V213 M217L43-V215 WeakPolarHBondContact CA-O 3.37Å; W44-V215 HydrophobicContact CB-CB 4.45Å; W44-V215 HydrophobicContact CE3-CB 3.99Å; W44-V215 HydrophobicContact CE3-CG1 4.02Å; W44-V215 HydrophobicContact CZ3-CG1 4.29Å; W44-V215 PolarHBondContact N-O 3.38Å; W44-V215 PolarHBondContact O-N 2.92Å; L57-V215 HydrophobicContact CD1-CB 3.69Å; L57-V215 HydrophobicContact CD1-CG1 3.66Å; L57-V215 HydrophobicContact CD1-CG2 3.63Å; V68-V215 WeakPolarHBondContact O-CA 3.34Å; L69-V215 HydrophobicContact CD1-CG2 3.69Å; L196-V215 HydrophobicContact CD2-CG1 3.87Å; V213-V215 HydrophobicContact CG1-CG2 4.19Å; V215-M217 HydrophobicContact CG1-CE 4.21Å
216V91.3Very high87.1Confident19 Ų1942.4 Ų42.412%0.11521%0.212CC..EExtended strand (participates in β ladder)trans-129.4121.7179.4-156.10000108.8L43 V68 N214 R218 Y223L43-V216 HydrophobicContact CD1-CB 4.44Å; L43-V216 HydrophobicContact CD1-CG1 4.13Å; L43-V216 HydrophobicContact CD1-CG2 3.89Å; V68-V216 HydrophobicContact CB-CB 3.85Å; V68-V216 HydrophobicContact CB-CG2 4.06Å; V68-V216 HydrophobicContact CG2-CB 4.06Å; V68-V216 PolarHBondContact N-O 3.13Å; V68-V216 PolarHBondContact O-N 3.46Å; N214-V216 VanDerWaalsContact ND2-CG2 3.32Å; N214-V216 WeakPolarHBondContact ND2-CG2 3.42Å; V216-R218 HydrophobicContact CG1-CB 4.5Å; V216-Y223 HydrophobicContact CG1-CE1 3.51Å
217M90.9Very high87.4Confident2 Ų234.4 Ų34.41%0.0118%0.176CC..EExtended strand (participates in β ladder)trans-115.299.9173.4-69.1178-166.400108G42 W44 L57 K59 M61 V67 L196 V215G42-M217 PolarHBondContact O-N 3.07Å; W44-M217 HydrophobicContact CH2-CB 4.49Å; W44-M217 HydrophobicContact CH2-CE 4.09Å; W44-M217 HydrophobicContact CH2-CG 4.26Å; W44-M217 HydrophobicContact CH2-SD 3.59Å; W44-M217 VanDerWaalsContact CH2-SD 3.59Å; W44-M217 HydrophobicContact CZ3-CB 4.11Å; W44-M217 HydrophobicContact CZ3-CE 3.94Å; W44-M217 HydrophobicContact CZ3-CG 3.78Å; W44-M217 HydrophobicContact CZ3-SD 3.66Å; L57-M217 HydrophobicContact CB-CE 4.09Å; K59-M217 HydrophobicContact CB-SD 3.72Å; K59-M217 HydrophobicContact CD-CB 3.77Å; K59-M217 HydrophobicContact CD-SD 3.95Å; K59-M217 HydrophobicContact CG-SD 4.47Å; M61-M217 HydrophobicContact CE-CG 4.45Å; M61-M217 HydrophobicContact CE-SD 3.79Å; M61-M217 HydrophobicContact SD-CB 3.82Å; M61-M217 HydrophobicContact SD-CG 3.86Å; M61-M217 HydrophobicContact SD-SD 3.71Å; V67-M217 HydrophobicContact CG1-CG 4.38Å; V67-M217 HydrophobicContact CG2-CG 4.44Å; L196-M217 HydrophobicContact CB-CE 3.73Å; L196-M217 HydrophobicContact CD2-CE 3.65Å; L196-M217 HydrophobicContact CG-CE 4.34Å; V215-M217 HydrophobicContact CG1-CE 4.21Å
218R88.4Confident87.8Confident132 Ų13235.1 Ų35.150%0.49818%0.178SC..EExtended strand (participates in β ladder)trans-130.9123.9-173.4-172.3-177.6176.3161.8-1.8111.2D66 V216 Y223D66-R218 PolarHBondContact N-O 2.75Å; D66-R218 PolarHBondContact O-N 2.93Å; V216-R218 HydrophobicContact CG1-CB 4.5Å; R218-Y223 HydrophobicContact CB-CD1 4.21Å; R218-Y223 HydrophobicContact CB-CE1 4.06Å; R218-Y223 HydrophobicContact CG-CD1 4.36Å; R218-Y223 HydrophobicContact CG-CD2 4.4Å; R218-Y223 HydrophobicContact CG-CE1 4.27Å; R218-Y223 HydrophobicContact CG-CE2 4.27Å; R218-Y223 HydrophobicContact CG-CG 4.44Å
219G86.9Confident88.2Confident15 Ų1535.7 Ų35.716%0.15517%0.167CC..BIsolated β-bridgetrans-102.3-176.8178.400000112.7H221 G222G219-H221 PolarHBondContact O-N 3Å; G219-G222 PolarHBondContact N-O 3.37Å; G219-G222 PolarHBondContact O-N 3.4Å; G219-G222 VanDerWaalsContact O-N 3.16Å
220K86.5Confident88.4Confident157 Ų15736.1 Ų36.168%0.68317%0.173SC*.THydrogen-bonded Turntrans-58.1-28.9174.1-70.2171.6175.4169.60113.2E64E64-K220 IonicContact OE2-NZ 2.77Å; E64-K220 PolarHBondContact OE2-NZ 3.42Å
221H83.9Confident88.3Confident93 Ų9333.6 Ų33.643%0.43116%0.159SC..THydrogen-bonded Turntrans-90.21-178.8-61.8-59.3000114.6F62 G219 N289F62-H221 AromaticContact CD1-CD2 3.96Å; F62-H221 AromaticContact CE1-CD2 3.87Å; F62-H221 HydrophobicContact CE2-CB 4.4Å; F62-H221 AromaticContact CZ-CD2 3.96Å; G219-H221 PolarHBondContact O-N 3Å; H221-N289 PolarHBondContact O-ND2 3.46Å; H221-N289 PolarHBondContact O-OD1 3.16Å; H221-N289 VanDerWaalsContact O-OD1 3.05Å
222G88.6Confident88.3Confident11 Ų1134.6 Ų34.611%0.11316%0.164CC..BIsolated β-bridgetrans108.4-145.2-175.500000112.2G219 N289G219-G222 PolarHBondContact N-O 3.37Å; G219-G222 PolarHBondContact O-N 3.4Å; G219-G222 VanDerWaalsContact O-N 3.16Å; G222-N289 VanDerWaalsContact CA-OD1 3.3Å; G222-N289 WeakPolarHBondContact CA-OD1 3.27Å
223Y87.8Confident88.5Confident31 Ų3136.5 Ų36.512%0.12217%0.173CC..SBendtrans-97.1-9.6-179-69.1-90.4000114.3K59 V216 R218 N289 V290 G292K59-Y223 WeakPolarHBondContact CE-O 3.34Å; K59-Y223 PolarHBondContact NZ-O 2.87Å; V216-Y223 HydrophobicContact CG1-CE1 3.51Å; R218-Y223 HydrophobicContact CB-CD1 4.21Å; R218-Y223 HydrophobicContact CB-CE1 4.06Å; R218-Y223 HydrophobicContact CG-CD1 4.36Å; R218-Y223 HydrophobicContact CG-CD2 4.4Å; R218-Y223 HydrophobicContact CG-CE1 4.27Å; R218-Y223 HydrophobicContact CG-CE2 4.27Å; R218-Y223 HydrophobicContact CG-CG 4.44Å; Y223-N289 WeakPolarHBondContact CD2-O 3.11Å; Y223-N289 PolarHBondContact N-O 3.34Å; Y223-N289 VanDerWaalsContact N-O 3.16Å; Y223-N289 PolarHBondContact N-OD1 2.9Å; Y223-V290 WeakPolarHBondContact CE2-O 3.29Å; Y223-G292 VanDerWaalsContact CB-CA 3.48Å
224I88.2Confident88.6Confident7 Ų737.8 Ų37.84%0.03618%0.178CC..  trans-63.1144.1-179.2-164.5164.2000112.1E228 W229 M232 Y285 N289I224-E228 HydrophobicContact CD1-CB 4.12Å; I224-E228 HydrophobicContact CG1-CB 3.82Å; I224-W229 HydrophobicContact CG2-CB 4.44Å; I224-M232 HydrophobicContact CD1-CB 3.89Å; I224-M232 HydrophobicContact CD1-CE 4.29Å; I224-M232 HydrophobicContact CD1-CG 4.37Å; I224-M232 HydrophobicContact CD1-SD 3.73Å; I224-Y285 HydrophobicContact CD1-CD1 4.41Å; I224-N289 HydrophobicContact CB-CB 4.13Å; I224-N289 WeakPolarHBondContact CB-OD1 3.16Å; I224-N289 WeakPolarHBondContact CG2-OD1 3.3Å; I224-N289 PolarHBondContact N-OD1 3.42Å
225S87.6Confident88.6Confident0 Ų036.3 Ų36.30%017%0.17CC..  trans-74.5159174.566.40000111.8E40 A60 T227 E228 W229E40-S225 WeakPolarHBondContact OE2-CB 3.49Å; A60-S225 VanDerWaalsContact O-CA 3.23Å; A60-S225 WeakPolarHBondContact O-CA 3.35Å; A60-S225 VanDerWaalsContact O-CB 3.29Å; A60-S225 WeakPolarHBondContact O-CB 3.45Å; S225-T227 PolarHBondContact O-N 3.47Å; S225-T227 PolarHBondContact OG-OG1 2.96Å; S225-T227 VanDerWaalsContact OG-OG1 3.1Å; S225-E228 PolarHBondContact O-N 3.47Å; S225-E228 WeakPolarHBondContact OG-CB 3.43Å; S225-E228 VanDerWaalsContact OG-CG 3.3Å; S225-E228 WeakPolarHBondContact OG-CG 3.47Å; S225-E228 PolarHBondContact OG-N 3.37Å; S225-E228 PolarHBondContact OG-OE1 3.34Å; S225-E228 PolarHBondContact OG-OE2 3Å; S225-W229 PolarHBondContact O-N 3.25Å; S225-W229 VanDerWaalsContact O-N 3.1Å
226I87.8Confident88.6Confident9 Ų941 Ų415%0.04619%0.193CC..THydrogen-bonded Turntrans-68.5-24.1177.3-172.8162.1000112.9A60 F62 N191 P230 W441A60-I226 HydrophobicContact CB-CG2 3.69Å; A60-I226 PolarHBondContact O-N 2.89Å; F62-I226 HydrophobicContact CD1-CB 4.33Å; F62-I226 HydrophobicContact CD1-CD1 3.65Å; F62-I226 HydrophobicContact CD1-CG1 4.02Å; F62-I226 HydrophobicContact CD2-CB 4.15Å; F62-I226 HydrophobicContact CE1-CB 4.15Å; F62-I226 HydrophobicContact CE1-CD1 3.77Å; F62-I226 HydrophobicContact CE1-CG1 3.69Å; F62-I226 HydrophobicContact CE2-CB 3.95Å; F62-I226 HydrophobicContact CE2-CG1 4.39Å; F62-I226 HydrophobicContact CG-CB 4.33Å; F62-I226 HydrophobicContact CG-CD1 4.22Å; F62-I226 HydrophobicContact CZ-CB 3.95Å; F62-I226 HydrophobicContact CZ-CD1 4.44Å; F62-I226 HydrophobicContact CZ-CG1 3.89Å; N191-I226 HydrophobicContact CB-CD1 3.65Å; I226-P230 WeakPolarHBondContact O-CD 3.34Å; I226-W441 HydrophobicContact CB-CZ3 4.49Å; I226-W441 HydrophobicContact CD1-CH2 3.93Å; I226-W441 HydrophobicContact CD1-CZ3 4.4Å; I226-W441 HydrophobicContact CG1-CH2 4.19Å; I226-W441 HydrophobicContact CG1-CZ3 4.14Å; I226-W441 HydrophobicContact CG2-CH2 3.91Å; I226-W441 HydrophobicContact CG2-CZ3 3.62Å
227T83.2Confident88.8Confident18 Ų1844.4 Ų44.411%0.1121%0.214CC..THydrogen-bonded Turntrans-76.1-31.6175.342.40000112.6A60 S225 W441A60-T227 HydrophobicContact CB-CG2 3.96Å; S225-T227 PolarHBondContact O-N 3.47Å; S225-T227 PolarHBondContact OG-OG1 2.96Å; S225-T227 VanDerWaalsContact OG-OG1 3.1Å; T227-W441 HydrophobicContact CG2-CE3 3.93Å; T227-W441 HydrophobicContact CG2-CZ3 4.35Å
228E86.4Confident89Confident22 Ų2244.8 Ų44.810%0.10322%0.215CC..THydrogen-bonded Turntrans-90.9-22.1-179.4-72.7158.9-157.100114.1P39 E40 I224 S225 L231 M232 Y285P39-E228 VanDerWaalsContact CA-OE1 3.27Å; P39-E228 WeakPolarHBondContact CA-OE1 3.37Å; P39-E228 WeakPolarHBondContact CB-OE2 3.39Å; E40-E228 PolarHBondContact N-OE1 2.83Å; E40-E228 PolarHBondContact N-OE2 3.37Å; I224-E228 HydrophobicContact CD1-CB 4.12Å; I224-E228 HydrophobicContact CG1-CB 3.82Å; S225-E228 PolarHBondContact O-N 3.47Å; S225-E228 WeakPolarHBondContact OG-CB 3.43Å; S225-E228 VanDerWaalsContact OG-CG 3.3Å; S225-E228 WeakPolarHBondContact OG-CG 3.47Å; S225-E228 PolarHBondContact OG-N 3.37Å; S225-E228 PolarHBondContact OG-OE1 3.34Å; S225-E228 PolarHBondContact OG-OE2 3Å; E228-L231 CarbonylContact O-C 3.56Å; E228-L231 WeakPolarHBondContact O-CA 3.46Å; E228-L231 WeakPolarHBondContact O-CB 3.47Å; E228-L231 PolarHBondContact O-N 3.34Å; E228-M232 PolarHBondContact O-N 3.45Å; E228-Y285 HydrophobicContact CB-CE1 4.15Å; E228-Y285 HydrophobicContact CG-CE1 4.16Å
229W89.3Confident89.3Confident94 Ų9439.3 Ų39.336%0.35620%0.198SC..Hα-helixtrans-56.7-43.5-178.6-173.588.3000114.1F62 I224 S225 L231 I233F62-W229 HydrophobicContact CE2-CB 4.44Å; F62-W229 HydrophobicContact CZ-CB 3.9Å; F62-W229 HydrophobicContact CZ-CD2 4.41Å; F62-W229 AromaticContact CZ-CG 3.95Å; F62-W229 HydrophobicContact CZ-CG 3.95Å; I224-W229 HydrophobicContact CG2-CB 4.44Å; S225-W229 PolarHBondContact O-N 3.25Å; S225-W229 VanDerWaalsContact O-N 3.1Å; W229-L231 VanDerWaalsContact C-N 3.31Å; W229-L231 PolarHBondContact O-N 3.42Å; W229-I233 HydrophobicContact CD2-CD1 3.97Å; W229-I233 HydrophobicContact CE3-CD1 3.79Å; W229-I233 HydrophobicContact CH2-CD1 3.47Å; W229-I233 VanDerWaalsContact CH2-CD1 3.47Å; W229-I233 HydrophobicContact CZ2-CD1 3.65Å; W229-I233 HydrophobicContact CZ3-CD1 3.53Å; W229-I233 PolarHBondContact O-N 2.9Å
230P90.5Very high89.7Confident26 Ų2640.1 Ų40.117%0.16921%0.206CC..Hα-helixtrans-64.8-35.3172.4-19.733.2000112.8I226 I233 F234 W445I226-P230 WeakPolarHBondContact O-CD 3.34Å; P230-I233 PolarHBondContact O-N 3.37Å; P230-F234 PolarHBondContact O-N 3.14Å; P230-W445 HydrophobicContact CB-CD2 3.8Å; P230-W445 HydrophobicContact CB-CE3 4.45Å; P230-W445 HydrophobicContact CB-CG 3.96Å; P230-W445 HydrophobicContact CB-CZ2 4.2Å; P230-W445 HydrophobicContact CG-CG 4.46Å
231L86.8Confident90.2Very high11 Ų1134.6 Ų34.66%0.05819%0.185CC..Hα-helixtrans-67.7-41.3-179.3-173.758000111.3E228 W229 I233 F234 Y235 Y285 W445E228-L231 CarbonylContact O-C 3.56Å; E228-L231 WeakPolarHBondContact O-CA 3.46Å; E228-L231 WeakPolarHBondContact O-CB 3.47Å; E228-L231 PolarHBondContact O-N 3.34Å; W229-L231 VanDerWaalsContact C-N 3.31Å; W229-L231 PolarHBondContact O-N 3.42Å; L231-I233 VanDerWaalsContact C-N 3.33Å; L231-I233 PolarHBondContact O-N 3.27Å; L231-F234 HydrophobicContact CD1-CD1 4.15Å; L231-F234 WeakPolarHBondContact O-CB 3.47Å; L231-F234 PolarHBondContact O-N 2.98Å; L231-Y235 HydrophobicContact CD1-CD2 4.02Å; L231-Y235 HydrophobicContact CD1-CE2 3.71Å; L231-Y235 HydrophobicContact CD2-CE2 4.29Å; L231-Y235 HydrophobicContact CG-CD2 3.92Å; L231-Y235 HydrophobicContact CG-CE2 3.72Å; L231-Y235 WeakPolarHBondContact O-CD2 3.48Å; L231-Y235 PolarHBondContact O-N 3.42Å; L231-Y285 VanDerWaalsContact CD2-OH 3.28Å; L231-Y285 WeakPolarHBondContact CD2-OH 3.48Å; L231-W445 HydrophobicContact CB-CB 4.22Å
232M89.2Confident90.7Very high23 Ų2330.2 Ų30.211%0.11317%0.165CC..Hα-helixtrans-56.5-45.7171.6-179.9-175.371.800111.5I224 E228 Y235 M236 Y285I224-M232 HydrophobicContact CD1-CB 3.89Å; I224-M232 HydrophobicContact CD1-CE 4.29Å; I224-M232 HydrophobicContact CD1-CG 4.37Å; I224-M232 HydrophobicContact CD1-SD 3.73Å; E228-M232 PolarHBondContact O-N 3.45Å; M232-Y235 PolarHBondContact O-N 2.87Å; M232-M236 HydrophobicContact CE-CE 4.46Å; M232-M236 HydrophobicContact CG-CE 4.45Å; M232-M236 WeakPolarHBondContact O-CG 3.27Å; M232-M236 PolarHBondContact O-N 2.91Å; M232-Y285 HydrophobicContact CB-CG 4.27Å; M232-Y285 HydrophobicContact CG-CG 4.49Å
233I92.1Very high91.1Very high61 Ų6133.3 Ų33.331%0.31318%0.178SC..Hα-helixtrans-64-43.8177.3-64.5169.1000111W229 P230 L231 Y235 M236 V237W229-I233 HydrophobicContact CD2-CD1 3.97Å; W229-I233 HydrophobicContact CE3-CD1 3.79Å; W229-I233 HydrophobicContact CH2-CD1 3.47Å; W229-I233 VanDerWaalsContact CH2-CD1 3.47Å; W229-I233 HydrophobicContact CZ2-CD1 3.65Å; W229-I233 HydrophobicContact CZ3-CD1 3.53Å; W229-I233 PolarHBondContact O-N 2.9Å; P230-I233 PolarHBondContact O-N 3.37Å; L231-I233 VanDerWaalsContact C-N 3.33Å; L231-I233 PolarHBondContact O-N 3.27Å; I233-Y235 VanDerWaalsContact C-N 3.33Å; I233-Y235 PolarHBondContact O-N 3.34Å; I233-M236 HydrophobicContact CB-CE 4.46Å; I233-M236 HydrophobicContact CG1-CE 4.06Å; I233-M236 PolarHBondContact O-N 2.94Å; I233-V237 HydrophobicContact CG2-CG2 4.45Å; I233-V237 WeakPolarHBondContact O-CG2 3.17Å; I233-V237 PolarHBondContact O-N 2.91Å
234F92.4Very high91.5Very high31 Ų3136.8 Ų36.814%0.13620%0.198CC..Hα-helixtrans-57.1-45.4174171.1-98.3000111.7P230 L231 M236 V237 M238 W445 A449 R452 F453P230-F234 PolarHBondContact O-N 3.14Å; L231-F234 HydrophobicContact CD1-CD1 4.15Å; L231-F234 WeakPolarHBondContact O-CB 3.47Å; L231-F234 PolarHBondContact O-N 2.98Å; F234-M236 PolarHBondContact O-N 3.39Å; F234-V237 PolarHBondContact O-N 3.47Å; F234-M238 HydrophobicContact CD1-CG 4.23Å; F234-M238 HydrophobicContact CD2-CG 3.97Å; F234-M238 HydrophobicContact CE1-CG 3.9Å; F234-M238 HydrophobicContact CE2-CG 3.61Å; F234-M238 HydrophobicContact CE2-SD 3.93Å; F234-M238 HydrophobicContact CG-CG 4.27Å; F234-M238 HydrophobicContact CZ-CE 4.39Å; F234-M238 HydrophobicContact CZ-CG 3.58Å; F234-M238 HydrophobicContact CZ-SD 4.1Å; F234-M238 WeakPolarHBondContact O-CB 3.14Å; F234-M238 WeakPolarHBondContact O-CG 3.33Å; F234-M238 PolarHBondContact O-N 3.42Å; F234-W445 HydrophobicContact CB-CZ3 4.46Å; F234-A449 HydrophobicContact CD1-CB 4.04Å; F234-A449 HydrophobicContact CD2-CB 4Å; F234-A449 HydrophobicContact CE1-CB 3.9Å; F234-A449 HydrophobicContact CE2-CB 3.86Å; F234-A449 HydrophobicContact CG-CB 4.08Å; F234-A449 HydrophobicContact CZ-CB 3.79Å; F234-A449 WeakPolarHBondContact CZ-O 3.31Å; F234-R452 HydrophobicContact CE1-CB 4.02Å; F234-R452 HydrophobicContact CZ-CB 4.07Å; F234-F453 HydrophobicContact CE2-CB 4.4Å; F234-F453 HydrophobicContact CZ-CB 4.38Å
235Y91.8Very high91.8Very high0 Ų037.6 Ų37.60%020%0.201CC..Hα-helixtrans-60.8-43.1176.2-86.7-74.1000112.6L231 M232 I233 M238 C239 K278 F281 C282 Y285 R452L231-Y235 HydrophobicContact CD1-CD2 4.02Å; L231-Y235 HydrophobicContact CD1-CE2 3.71Å; L231-Y235 HydrophobicContact CD2-CE2 4.29Å; L231-Y235 HydrophobicContact CG-CD2 3.92Å; L231-Y235 HydrophobicContact CG-CE2 3.72Å; L231-Y235 WeakPolarHBondContact O-CD2 3.48Å; L231-Y235 PolarHBondContact O-N 3.42Å; M232-Y235 PolarHBondContact O-N 2.87Å; I233-Y235 VanDerWaalsContact C-N 3.33Å; I233-Y235 PolarHBondContact O-N 3.34Å; Y235-M238 PolarHBondContact O-N 2.95Å; Y235-C239 WeakPolarHBondContact O-CB 3.31Å; Y235-C239 PolarHBondContact O-N 2.89Å; Y235-K278 HydrophobicContact CD1-CD 3.62Å; Y235-K278 HydrophobicContact CE1-CD 3.84Å; Y235-F281 HydrophobicContact CD1-CB 3.52Å; Y235-F281 HydrophobicContact CD1-CD2 4.37Å; Y235-F281 HydrophobicContact CD1-CG 4.17Å; Y235-F281 HydrophobicContact CD2-CB 4.46Å; Y235-F281 HydrophobicContact CE1-CB 3.43Å; Y235-F281 VanDerWaalsContact CE1-CB 3.43Å; Y235-F281 HydrophobicContact CE1-CD1 4.4Å; Y235-F281 AromaticContact CE1-CD2 3.54Å; Y235-F281 HydrophobicContact CE1-CD2 3.54Å; Y235-F281 HydrophobicContact CE1-CE2 4.4Å; Y235-F281 AromaticContact CE1-CG 3.54Å; Y235-F281 HydrophobicContact CE1-CG 3.54Å; Y235-F281 HydrophobicContact CE2-CB 4.41Å; Y235-F281 HydrophobicContact CG-CB 4.06Å; Y235-F281 AromaticContact CZ-CD2 4Å; Y235-F281 AromaticContact CZ-CG 3.77Å; Y235-C282 PolarHBondContact O-SG 2.93Å; Y235-Y285 AromaticContact CD2-CD2 3.95Å; Y235-Y285 HydrophobicContact CD2-CD2 3.95Å; Y235-Y285 AromaticContact CD2-CE2 3.54Å; Y235-Y285 HydrophobicContact CD2-CE2 3.54Å; Y235-Y285 HydrophobicContact CE2-CD2 4.35Å; Y235-Y285 AromaticContact CE2-CE2 3.51Å; Y235-Y285 HydrophobicContact CE2-CE2 3.51Å; Y235-Y285 HydrophobicContact CG-CE2 4.47Å; Y235-R452 PolarHBondContact OH-NE 3.2Å; Y235-R452 VanDerWaalsContact OH-NE 3.07Å; Y235-R452 PolarHBondContact OH-NH2 3.19Å; Y235-R452 VanDerWaalsContact OH-NH2 3.16Å
236M92.2Very high92.2Very high98 Ų9839 Ų3948%0.48321%0.212SC..Hα-helixtrans-61.9-47.5176.4-70.5-170.1-68.300112.3M232 I233 F234 M238 C239 G240M232-M236 HydrophobicContact CE-CE 4.46Å; M232-M236 HydrophobicContact CG-CE 4.45Å; M232-M236 WeakPolarHBondContact O-CG 3.27Å; M232-M236 PolarHBondContact O-N 2.91Å; I233-M236 HydrophobicContact CB-CE 4.46Å; I233-M236 HydrophobicContact CG1-CE 4.06Å; I233-M236 PolarHBondContact O-N 2.94Å; F234-M236 PolarHBondContact O-N 3.39Å; M236-M238 PolarHBondContact O-N 3.44Å; M236-C239 WeakPolarHBondContact O-CB 3.41Å; M236-C239 PolarHBondContact O-N 2.91Å; M236-G240 PolarHBondContact O-N 3.35Å; M236-G240 VanDerWaalsContact O-N 3.12Å
237V95.6Very high92.6Very high91 Ų9143.3 Ų43.355%0.55224%0.235SC*.Hα-helixtrans-61.9-45.5177.6173.20000110.6I233 F234 C239 G240 V241I233-V237 HydrophobicContact CG2-CG2 4.45Å; I233-V237 WeakPolarHBondContact O-CG2 3.17Å; I233-V237 PolarHBondContact O-N 2.91Å; F234-V237 PolarHBondContact O-N 3.47Å; V237-C239 VanDerWaalsContact C-N 3.33Å; V237-C239 PolarHBondContact O-N 3.37Å; V237-G240 PolarHBondContact O-N 3.02Å; V237-V241 WeakPolarHBondContact O-CG2 3.2Å; V237-V241 PolarHBondContact O-N 3.04Å
238M93.3Very high93.1Very high10 Ų1046.3 Ų46.35%0.04925%0.25CC..Hα-helixtrans-64.7-36177.6-68.6-62.9-69.900111.9F234 Y235 M236 G240 V241 Y242 K278 S456F234-M238 HydrophobicContact CD1-CG 4.23Å; F234-M238 HydrophobicContact CD2-CG 3.97Å; F234-M238 HydrophobicContact CE1-CG 3.9Å; F234-M238 HydrophobicContact CE2-CG 3.61Å; F234-M238 HydrophobicContact CE2-SD 3.93Å; F234-M238 HydrophobicContact CG-CG 4.27Å; F234-M238 HydrophobicContact CZ-CE 4.39Å; F234-M238 HydrophobicContact CZ-CG 3.58Å; F234-M238 HydrophobicContact CZ-SD 4.1Å; F234-M238 WeakPolarHBondContact O-CB 3.14Å; F234-M238 WeakPolarHBondContact O-CG 3.33Å; F234-M238 PolarHBondContact O-N 3.42Å; Y235-M238 PolarHBondContact O-N 2.95Å; M236-M238 PolarHBondContact O-N 3.44Å; M238-G240 VanDerWaalsContact C-N 3.32Å; M238-G240 PolarHBondContact O-N 3.13Å; M238-V241 PolarHBondContact O-N 2.97Å; M238-Y242 HydrophobicContact CE-CE2 4.22Å; M238-Y242 WeakPolarHBondContact O-CD2 3.38Å; M238-Y242 PolarHBondContact O-N 3.36Å; M238-K278 HydrophobicContact CB-CD 4.37Å; M238-K278 HydrophobicContact CB-CG 4.49Å; M238-S456 VanDerWaalsContact CE-CB 3.45Å
239C95Very high93.5Very high18 Ų1845.6 Ų45.612%0.12225%0.246CC..Hα-helixtrans-58.7-45.1173-167.30000111Y235 M236 V237 V241 Y242 I243 K278Y235-C239 WeakPolarHBondContact O-CB 3.31Å; Y235-C239 PolarHBondContact O-N 2.89Å; M236-C239 WeakPolarHBondContact O-CB 3.41Å; M236-C239 PolarHBondContact O-N 2.91Å; V237-C239 VanDerWaalsContact C-N 3.33Å; V237-C239 PolarHBondContact O-N 3.37Å; C239-V241 PolarHBondContact O-N 3.35Å; C239-Y242 PolarHBondContact O-N 2.89Å; C239-I243 WeakPolarHBondContact O-CG1 3.33Å; C239-I243 PolarHBondContact O-N 2.95Å; C239-K278 HydrophobicContact CB-CB 3.9Å
240G95.6Very high93.7Very high32 Ų3248 Ų4833%0.3326%0.259SS..Hα-helixtrans-58.3-43.6172.200000113.2M236 V237 M238 Y242 I243 L244M236-G240 PolarHBondContact O-N 3.35Å; M236-G240 VanDerWaalsContact O-N 3.12Å; V237-G240 PolarHBondContact O-N 3.02Å; M238-G240 VanDerWaalsContact C-N 3.32Å; M238-G240 PolarHBondContact O-N 3.13Å; G240-Y242 PolarHBondContact O-N 3.14Å; G240-I243 PolarHBondContact O-N 3.46Å; G240-L244 WeakPolarHBondContact O-CG 3.48Å; G240-L244 PolarHBondContact O-N 3.25Å
241V96.2Very high93.7Very high41 Ų4150.6 Ų50.625%0.24828%0.275CS..Hα-helixtrans-61.7-42.3175.4173.70000112V237 M238 C239 L244 Y245V237-V241 WeakPolarHBondContact O-CG2 3.2Å; V237-V241 PolarHBondContact O-N 3.04Å; M238-V241 PolarHBondContact O-N 2.97Å; C239-V241 PolarHBondContact O-N 3.35Å; V241-L244 WeakPolarHBondContact O-CB 3.47Å; V241-L244 PolarHBondContact O-N 2.72Å; V241-Y245 HydrophobicContact CG1-CD1 4.18Å; V241-Y245 HydrophobicContact CG1-CE1 3.5Å; V241-Y245 HydrophobicContact CG1-CE2 4.01Å; V241-Y245 WeakPolarHBondContact CG1-OH 3.5Å; V241-Y245 VanDerWaalsContact O-CD1 3.29Å; V241-Y245 WeakPolarHBondContact O-CD1 3.27Å; V241-Y245 PolarHBondContact O-N 3.04Å
242Y95.6Very high93.9Very high1 Ų153 Ų530%0.00428%0.283CS..Hα-helixtrans-68.7-33.8176.9-89.6-90.2000113M238 C239 G240 Y245 A246 K278 F455 L459M238-Y242 HydrophobicContact CE-CE2 4.22Å; M238-Y242 WeakPolarHBondContact O-CD2 3.38Å; M238-Y242 PolarHBondContact O-N 3.36Å; C239-Y242 PolarHBondContact O-N 2.89Å; G240-Y242 PolarHBondContact O-N 3.14Å; Y242-Y245 PolarHBondContact O-N 3.48Å; Y242-A246 WeakPolarHBondContact O-CB 3.29Å; Y242-A246 PolarHBondContact O-N 3.21Å; Y242-K278 HydrophobicContact CD2-CG 4Å; Y242-K278 HydrophobicContact CE2-CG 4.39Å; Y242-F455 VanDerWaalsContact OH-CD1 3.31Å; Y242-F455 WeakPolarHBondContact OH-CD1 3.49Å; Y242-F455 WeakPolarHBondContact OH-CE1 3.5Å; Y242-L459 HydrophobicContact CD1-CD2 4.5Å; Y242-L459 HydrophobicContact CE1-CD2 3.59Å
243I96.1Very high93.9Very high75 Ų7552.7 Ų52.739%0.38528%0.284SS..Hα-helixtrans-62.9-44.6170.7-69.2164.6000110.1C239 G240 Y245 A246 L247 M275C239-I243 WeakPolarHBondContact O-CG1 3.33Å; C239-I243 PolarHBondContact O-N 2.95Å; G240-I243 PolarHBondContact O-N 3.46Å; I243-Y245 VanDerWaalsContact C-N 3.35Å; I243-Y245 PolarHBondContact O-N 3.41Å; I243-A246 PolarHBondContact O-N 3.23Å; I243-L247 HydrophobicContact CG2-CD1 3.91Å; I243-L247 HydrophobicContact CG2-CG 4.38Å; I243-L247 WeakPolarHBondContact O-CB 3.41Å; I243-L247 VanDerWaalsContact O-CG 3.3Å; I243-L247 WeakPolarHBondContact O-CG 3.26Å; I243-L247 PolarHBondContact O-N 2.79Å; I243-M275 HydrophobicContact CG1-CG 4.18Å; I243-M275 HydrophobicContact CG1-SD 4.27Å
244L96.2Very high93.8Very high104 Ų10452.6 Ų52.655%0.54529%0.292SS..Hα-helixtrans-61.1-41.4174.9-69172.2000112.1G240 V241 L247 L248G240-L244 WeakPolarHBondContact O-CG 3.48Å; G240-L244 PolarHBondContact O-N 3.25Å; V241-L244 WeakPolarHBondContact O-CB 3.47Å; V241-L244 PolarHBondContact O-N 2.72Å; L244-L247 PolarHBondContact O-N 2.93Å; L244-L248 WeakPolarHBondContact O-CB 3.39Å; L244-L248 VanDerWaalsContact O-CG 3.23Å; L244-L248 WeakPolarHBondContact O-CG 3.45Å; L244-L248 PolarHBondContact O-N 3.25Å
245Y96.1Very high93.7Very high24 Ų2455.6 Ų55.69%0.09432%0.316CS..Hα-helixtrans-62.3-44.8174.7-680.5000111.8V241 Y242 I243 L248 W249 S456 L459 L460 M463V241-Y245 HydrophobicContact CG1-CD1 4.18Å; V241-Y245 HydrophobicContact CG1-CE1 3.5Å; V241-Y245 HydrophobicContact CG1-CE2 4.01Å; V241-Y245 WeakPolarHBondContact CG1-OH 3.5Å; V241-Y245 VanDerWaalsContact O-CD1 3.29Å; V241-Y245 WeakPolarHBondContact O-CD1 3.27Å; V241-Y245 PolarHBondContact O-N 3.04Å; Y242-Y245 PolarHBondContact O-N 3.48Å; I243-Y245 VanDerWaalsContact C-N 3.35Å; I243-Y245 PolarHBondContact O-N 3.41Å; Y245-L248 PolarHBondContact O-N 2.85Å; Y245-W249 WeakPolarHBondContact O-CB 3.34Å; Y245-W249 PolarHBondContact O-N 3.38Å; Y245-S456 WeakPolarHBondContact CE2-OG 3.45Å; Y245-S456 PolarHBondContact OH-OG 2.98Å; Y245-L459 HydrophobicContact CD2-CD2 3.99Å; Y245-L459 HydrophobicContact CE2-CD2 4.27Å; Y245-L460 HydrophobicContact CD1-CD1 4.3Å; Y245-L460 HydrophobicContact CE1-CB 4.49Å; Y245-L460 HydrophobicContact CE1-CD1 3.71Å; Y245-L460 HydrophobicContact CE1-CG 4.46Å; Y245-L460 HydrophobicContact CE2-CB 4.36Å; Y245-M463 HydrophobicContact CD1-CE 4.18Å; Y245-M463 HydrophobicContact CG-CE 4.35Å; Y245-M463 HydrophobicContact CG-SD 4.12Å
246A95.4Very high93.4Very high29 Ų2959.7 Ų59.724%0.2433%0.332CS..Hα-helixtrans-61.4-44.3177.700000111.7Y242 I243 F250 I271 M275Y242-A246 WeakPolarHBondContact O-CB 3.29Å; Y242-A246 PolarHBondContact O-N 3.21Å; I243-A246 PolarHBondContact O-N 3.23Å; A246-F250 WeakPolarHBondContact O-CB 3.45Å; A246-F250 PolarHBondContact O-N 2.97Å; A246-I271 HydrophobicContact CB-CG2 3.97Å; A246-M275 HydrophobicContact CB-SD 4.28Å
247L95.6Very high93Very high100 Ų10064.2 Ų64.252%0.52434%0.344SS..Hα-helixtrans-65.2-48.7177.5-70.1171.6000112.2I243 L244 W249 F250 V251I243-L247 HydrophobicContact CG2-CD1 3.91Å; I243-L247 HydrophobicContact CG2-CG 4.38Å; I243-L247 WeakPolarHBondContact O-CB 3.41Å; I243-L247 VanDerWaalsContact O-CG 3.3Å; I243-L247 WeakPolarHBondContact O-CG 3.26Å; I243-L247 PolarHBondContact O-N 2.79Å; L244-L247 PolarHBondContact O-N 2.93Å; L247-W249 PolarHBondContact O-N 3.33Å; L247-F250 PolarHBondContact O-N 3.14Å; L247-V251 WeakPolarHBondContact O-CG2 3.25Å; L247-V251 PolarHBondContact O-N 3.45Å
248L93.8Very high92.3Very high81 Ų8169.3 Ų69.342%0.42436%0.358SS..Hα-helixtrans-61.1-44.4178.2-71.8170.6000111.6L244 Y245 V251 W252 M463L244-L248 WeakPolarHBondContact O-CB 3.39Å; L244-L248 VanDerWaalsContact O-CG 3.23Å; L244-L248 WeakPolarHBondContact O-CG 3.45Å; L244-L248 PolarHBondContact O-N 3.25Å; Y245-L248 PolarHBondContact O-N 2.85Å; L248-V251 PolarHBondContact O-N 3.17Å; L248-W252 PolarHBondContact O-N 3.43Å; L248-W252 VanDerWaalsContact O-N 3.1Å; L248-M463 HydrophobicContact CB-CE 4.17Å; L248-M463 HydrophobicContact CD1-CE 4.32Å
249W94.6Very high91.7Very high8 Ų871.1 Ų71.13%0.0337%0.369CS..Hα-helixtrans-66.4-41.1177.5-168.5-104.3000112.3Y245 L247 W252 A253 Q264 I267 I271 M463Y245-W249 WeakPolarHBondContact O-CB 3.34Å; Y245-W249 PolarHBondContact O-N 3.38Å; L247-W249 PolarHBondContact O-N 3.33Å; W249-W252 AromaticContact CE3-CE3 3.94Å; W249-W252 HydrophobicContact CE3-CE3 3.94Å; W249-W252 HydrophobicContact CE3-CZ3 4.33Å; W249-W252 HydrophobicContact CZ3-CE3 4.4Å; W249-W252 PolarHBondContact O-N 3.39Å; W249-A253 WeakPolarHBondContact O-CB 3.46Å; W249-A253 PolarHBondContact O-N 3.4Å; W249-Q264 HydrophobicContact CH2-CG 4.2Å; W249-Q264 HydrophobicContact CZ2-CB 3.81Å; W249-Q264 HydrophobicContact CZ2-CG 4Å; W249-Q264 PolarHBondContact NE1-O 2.72Å; W249-I267 HydrophobicContact CD2-CG2 4.22Å; W249-I267 HydrophobicContact CE3-CG2 4.39Å; W249-I267 HydrophobicContact CH2-CB 4.12Å; W249-I267 HydrophobicContact CH2-CD1 3.83Å; W249-I267 HydrophobicContact CH2-CG2 3.72Å; W249-I267 HydrophobicContact CZ2-CB 3.66Å; W249-I267 HydrophobicContact CZ2-CD1 4.09Å; W249-I267 HydrophobicContact CZ2-CG1 4.48Å; W249-I267 HydrophobicContact CZ2-CG2 3.53Å; W249-I267 HydrophobicContact CZ3-CG2 4.16Å; W249-I271 HydrophobicContact CB-CD1 3.87Å; W249-I271 HydrophobicContact CD2-CD1 4.02Å; W249-I271 HydrophobicContact CG-CD1 3.72Å; W249-M463 HydrophobicContact CB-SD 4.37Å; W249-M463 HydrophobicContact CD2-CG 4.23Å; W249-M463 HydrophobicContact CE3-CG 3.33Å; W249-M463 HydrophobicContact CE3-SD 4.36Å; W249-M463 HydrophobicContact CZ3-CG 3.74Å; W249-M463 WeakPolarHBondContact CZ3-O 3.48Å
250F93.2Very high91Very high144 Ų14471.4 Ų71.463%0.63237%0.369SS*.Hα-helixtrans-61.7-43.6176179.4-99.9000111.7A246 L247 A253 A254A246-F250 WeakPolarHBondContact O-CB 3.45Å; A246-F250 PolarHBondContact O-N 2.97Å; L247-F250 PolarHBondContact O-N 3.14Å; F250-A253 PolarHBondContact O-N 3.01Å; F250-A254 VanDerWaalsContact O-CB 3.29Å; F250-A254 WeakPolarHBondContact O-CB 3.37Å; F250-A254 PolarHBondContact O-N 3.49Å
251V92.2Very high90.4Very high81 Ų8171.3 Ų71.349%0.49136%0.36SS..Hα-helixtrans-60.9-48.9175.9169.20000111.1L247 L248 A253 A254 C255L247-V251 WeakPolarHBondContact O-CG2 3.25Å; L247-V251 PolarHBondContact O-N 3.45Å; L248-V251 PolarHBondContact O-N 3.17Å; V251-A253 PolarHBondContact O-N 3.36Å; V251-A254 PolarHBondContact O-N 3.27Å; V251-C255 PolarHBondContact O-N 3.48Å; V251-C255 PolarHBondContact O-SG 2.91Å
252W90.8Very high89.8Confident62 Ų6278.3 Ų78.324%0.23538%0.382CS..Hα-helixtrans-63.5-40.7176.4-64.9-32.3000112.5L248 W249 C255 Y256 M463 F464 R467 P468L248-W252 PolarHBondContact O-N 3.43Å; L248-W252 VanDerWaalsContact O-N 3.1Å; W249-W252 AromaticContact CE3-CE3 3.94Å; W249-W252 HydrophobicContact CE3-CE3 3.94Å; W249-W252 HydrophobicContact CE3-CZ3 4.33Å; W249-W252 HydrophobicContact CZ3-CE3 4.4Å; W249-W252 PolarHBondContact O-N 3.39Å; W252-C255 PolarHBondContact O-N 2.96Å; W252-Y256 WeakPolarHBondContact O-CD2 3.25Å; W252-Y256 PolarHBondContact O-N 3.26Å; W252-M463 HydrophobicContact CH2-CE 4.34Å; W252-M463 HydrophobicContact CZ3-CE 3.98Å; W252-M463 HydrophobicContact CZ3-CG 4.19Å; W252-F464 HydrophobicContact CH2-CD1 4.01Å; W252-F464 AromaticContact CH2-CE1 3.85Å; W252-F464 HydrophobicContact CH2-CE1 3.85Å; W252-F464 HydrophobicContact CZ2-CE1 4.44Å; W252-R467 HydrophobicContact CE3-CB 4.27Å; W252-R467 HydrophobicContact CZ3-CB 4.48Å; W252-P468 HydrophobicContact CB-CB 4.47Å; W252-P468 HydrophobicContact CB-CG 4.08Å
253A89Confident89.2Confident16 Ų1678.6 Ų78.613%0.13238%0.384CS..Hα-helixtrans-65.7-37.2178.200000112.3W249 F250 V251 Y256 W257 L260W249-A253 WeakPolarHBondContact O-CB 3.46Å; W249-A253 PolarHBondContact O-N 3.4Å; F250-A253 PolarHBondContact O-N 3.01Å; V251-A253 PolarHBondContact O-N 3.36Å; A253-Y256 CarbonylContact O-C 3.55Å; A253-W257 WeakPolarHBondContact O-CA 3.18Å; A253-W257 VanDerWaalsContact O-CB 3.31Å; A253-W257 WeakPolarHBondContact O-CB 3.43Å; A253-W257 PolarHBondContact O-N 2.7Å; A253-L260 HydrophobicContact CB-CD1 4.27Å; A253-L260 HydrophobicContact CB-CD2 4.21Å
254A89.5Confident88.9Confident58 Ų5875.1 Ų75.148%0.47937%0.366SS..Hα-helixtrans-68.6-45.3175.900000111.9F250 V251 Y256 W257F250-A254 VanDerWaalsContact O-CB 3.29Å; F250-A254 WeakPolarHBondContact O-CB 3.37Å; F250-A254 PolarHBondContact O-N 3.49Å; V251-A254 PolarHBondContact O-N 3.27Å; A254-Y256 VanDerWaalsContact C-N 3.26Å; A254-Y256 PolarHBondContact O-N 2.98Å; A254-W257 PolarHBondContact O-N 3.18Å
255C89.2Confident88.6Confident94 Ų9475.7 Ų75.764%0.63536%0.364SS*.Hα-helixtrans-60.4-33.5177.8-71.10000113.3V251 W252V251-C255 PolarHBondContact O-N 3.48Å; V251-C255 PolarHBondContact O-SG 2.91Å; W252-C255 PolarHBondContact O-N 2.96Å
256Y85.4Confident88.3Confident87 Ų8780.3 Ų80.334%0.34138%0.382SS..THydrogen-bonded Turntrans-117.728.1-176.5-60.7-73.3000113W252 A253 A254 K258 D259 P468 A470W252-Y256 WeakPolarHBondContact O-CD2 3.25Å; W252-Y256 PolarHBondContact O-N 3.26Å; A253-Y256 CarbonylContact O-C 3.55Å; A254-Y256 VanDerWaalsContact C-N 3.26Å; A254-Y256 PolarHBondContact O-N 2.98Å; Y256-K258 PolarHBondContact O-N 3.26Å; Y256-D259 PolarHBondContact O-N 2.73Å; Y256-P468 HydrophobicContact CD2-CB 3.8Å; Y256-P468 HydrophobicContact CG-CB 4.08Å; Y256-A470 HydrophobicContact CD1-CB 4.15Å; Y256-A470 HydrophobicContact CE1-CB 3.9Å
257W84.8Confident88.1Confident193 Ų19379 Ų7973%0.73137%0.371SS*.G310 helixtrans-59-28.1-168.6-168.629.4000114.3A253 A254A253-W257 WeakPolarHBondContact O-CA 3.18Å; A253-W257 VanDerWaalsContact O-CB 3.31Å; A253-W257 WeakPolarHBondContact O-CB 3.43Å; A253-W257 PolarHBondContact O-N 2.7Å; A254-W257 PolarHBondContact O-N 3.18Å
258K81.8Confident88.1Confident197 Ų19775.8 Ų75.886%0.85736%0.358SS*.G310 helixtrans-71-26.7177.3-68.1178.5178.5172.80113.7Y256Y256-K258 PolarHBondContact O-N 3.26Å
259D80Confident88.1Confident49 Ų4973.3 Ų73.326%0.26235%0.353SS..G310 helixtrans-107.512.7-171.5-63-59.8000113.3Y256 L261 Q473Y256-D259 PolarHBondContact O-N 2.73Å; D259-L261 PolarHBondContact O-N 3.49Å; D259-Q473 HydrophobicContact CB-CG 4.27Å
260L80.9Confident88.1Confident24 Ų2473.1 Ų73.113%0.12635%0.352CS..  trans-68124.7-172.4-125.272.6000113A253 Q264 F265 P468A253-L260 HydrophobicContact CB-CD1 4.27Å; A253-L260 HydrophobicContact CB-CD2 4.21Å; L260-Q264 HydrophobicContact CD2-CB 4.48Å; L260-Q264 HydrophobicContact CG-CB 4.13Å; L260-F265 HydrophobicContact CB-CE2 4.03Å; L260-F265 HydrophobicContact CB-CZ 4.13Å; L260-F265 HydrophobicContact CD2-CD1 4.35Å; L260-F265 HydrophobicContact CD2-CD2 4.49Å; L260-F265 HydrophobicContact CD2-CE1 3.82Å; L260-F265 HydrophobicContact CD2-CE2 3.99Å; L260-F265 HydrophobicContact CD2-CZ 3.63Å; L260-F265 HydrophobicContact CG-CE2 4.48Å; L260-F265 HydrophobicContact CG-CZ 4.47Å; L260-P468 HydrophobicContact CD1-CB 4.01Å; L260-P468 HydrophobicContact CD1-CG 3.9Å
261L82.1Confident88.2Confident29 Ų2966.4 Ų66.415%0.15232%0.323CS..  trans-78.4150.2176-69.7169.6000110.8D259 I263 Q264 N472 A476D259-L261 PolarHBondContact O-N 3.49Å; L261-I263 PolarHBondContact O-N 3.12Å; L261-I263 VanDerWaalsContact O-N 3.1Å; L261-Q264 HydrophobicContact CB-CG 4.35Å; L261-Q264 WeakPolarHBondContact O-CB 3.38Å; L261-Q264 PolarHBondContact O-N 3.26Å; L261-N472 HydrophobicContact CD1-CB 4.23Å; L261-A476 HydrophobicContact CD2-CB 4.36Å
262R83.1Confident88.4Confident189 Ų18968.1 Ų68.171%0.71332%0.324SS*.Hα-helixtrans-51.3-40.9178.6-63.3-173.5-169.3-140.4-0.3112.6Q264 F265R262-Q264 PolarHBondContact O-N 3.49Å; R262-F265 PolarHBondContact O-N 2.89Å
263I84.6Confident88.5Confident6 Ų666.3 Ų66.33%0.03132%0.319CS..Hα-helixtrans-59.4-32.9178.9-54.6167.4000112L261 F265 W266 I267 V320 Y324L261-I263 PolarHBondContact O-N 3.12Å; L261-I263 VanDerWaalsContact O-N 3.1Å; I263-F265 VanDerWaalsContact C-N 3.29Å; I263-F265 PolarHBondContact O-N 3.46Å; I263-W266 WeakPolarHBondContact O-CA 3.46Å; I263-W266 WeakPolarHBondContact O-CB 3.28Å; I263-W266 PolarHBondContact O-N 3.46Å; I263-I267 HydrophobicContact CG2-CD1 4.17Å; I263-I267 HydrophobicContact CG2-CG1 4.42Å; I263-I267 WeakPolarHBondContact O-CG1 3.35Å; I263-I267 PolarHBondContact O-N 3.18Å; I263-V320 HydrophobicContact CG2-CG2 4.05Å; I263-Y324 WeakPolarHBondContact CD1-O 3.14Å
264Q89.6Confident88.8Confident3 Ų365.6 Ų65.61%0.01431%0.313CS..Hα-helixtrans-70-27.5-177.5-69.1170.9-31.600112.2W249 L260 L261 R262 A268 W466W249-Q264 HydrophobicContact CH2-CG 4.2Å; W249-Q264 HydrophobicContact CZ2-CB 3.81Å; W249-Q264 HydrophobicContact CZ2-CG 4Å; W249-Q264 PolarHBondContact NE1-O 2.72Å; L260-Q264 HydrophobicContact CD2-CB 4.48Å; L260-Q264 HydrophobicContact CG-CB 4.13Å; L261-Q264 HydrophobicContact CB-CG 4.35Å; L261-Q264 WeakPolarHBondContact O-CB 3.38Å; L261-Q264 PolarHBondContact O-N 3.26Å; R262-Q264 PolarHBondContact O-N 3.49Å; Q264-A268 WeakPolarHBondContact O-CB 3.26Å; Q264-A268 PolarHBondContact O-N 3.26Å; Q264-W466 PolarHBondContact NE2-O 2.85Å
265F88.7Confident89Confident116 Ų11665.2 Ų65.251%0.50930%0.302SS..Hα-helixtrans-70.1-34.3167.9-64.6-77.7000112.4L260 R262 I263 A268 G269L260-F265 HydrophobicContact CB-CE2 4.03Å; L260-F265 HydrophobicContact CB-CZ 4.13Å; L260-F265 HydrophobicContact CD2-CD1 4.35Å; L260-F265 HydrophobicContact CD2-CD2 4.49Å; L260-F265 HydrophobicContact CD2-CE1 3.82Å; L260-F265 HydrophobicContact CD2-CE2 3.99Å; L260-F265 HydrophobicContact CD2-CZ 3.63Å; L260-F265 HydrophobicContact CG-CE2 4.48Å; L260-F265 HydrophobicContact CG-CZ 4.47Å; R262-F265 PolarHBondContact O-N 2.89Å; I263-F265 VanDerWaalsContact C-N 3.29Å; I263-F265 PolarHBondContact O-N 3.46Å; F265-A268 PolarHBondContact O-N 3.17Å; F265-G269 PolarHBondContact O-N 3.01Å
266W89.9Confident89.4Confident121 Ų12162.6 Ų62.646%0.45828%0.283SS..Hα-helixtrans-67.7-41.7173-72.179.7000111.5I263 G269 V270 L312 L316I263-W266 WeakPolarHBondContact O-CA 3.46Å; I263-W266 WeakPolarHBondContact O-CB 3.28Å; I263-W266 PolarHBondContact O-N 3.46Å; W266-G269 PolarHBondContact O-N 3.4Å; W266-V270 WeakPolarHBondContact O-CG2 3.32Å; W266-V270 PolarHBondContact O-N 3.35Å; W266-L312 HydrophobicContact CE3-CD2 4.28Å; W266-L312 HydrophobicContact CZ3-CD2 3.64Å; W266-L316 HydrophobicContact CB-CD1 4.22Å
267I92.4Very high89.8Confident1 Ų158.5 Ų58.51%0.00527%0.267CS..Hα-helixtrans-59.6-47.6172.9-63.8166.2000110.2W249 I263 G269 V270 I271 L316 I462 W466W249-I267 HydrophobicContact CD2-CG2 4.22Å; W249-I267 HydrophobicContact CE3-CG2 4.39Å; W249-I267 HydrophobicContact CH2-CB 4.12Å; W249-I267 HydrophobicContact CH2-CD1 3.83Å; W249-I267 HydrophobicContact CH2-CG2 3.72Å; W249-I267 HydrophobicContact CZ2-CB 3.66Å; W249-I267 HydrophobicContact CZ2-CD1 4.09Å; W249-I267 HydrophobicContact CZ2-CG1 4.48Å; W249-I267 HydrophobicContact CZ2-CG2 3.53Å; W249-I267 HydrophobicContact CZ3-CG2 4.16Å; I263-I267 HydrophobicContact CG2-CD1 4.17Å; I263-I267 HydrophobicContact CG2-CG1 4.42Å; I263-I267 WeakPolarHBondContact O-CG1 3.35Å; I263-I267 PolarHBondContact O-N 3.18Å; I267-G269 VanDerWaalsContact C-N 3.32Å; I267-G269 PolarHBondContact O-N 2.95Å; I267-V270 PolarHBondContact O-N 3.37Å; I267-I271 HydrophobicContact CG2-CD1 3.79Å; I267-I271 HydrophobicContact CG2-CG1 4.45Å; I267-I271 WeakPolarHBondContact O-CG1 3.44Å; I267-I271 PolarHBondContact O-N 3.44Å; I267-L316 HydrophobicContact CB-CD1 4.38Å; I267-L316 HydrophobicContact CG1-CD1 3.8Å; I267-L316 HydrophobicContact CG1-CD2 4.33Å; I267-L316 HydrophobicContact CG1-CG 4.45Å; I267-I462 HydrophobicContact CD1-CG2 4.02Å; I267-I462 HydrophobicContact CG1-CG2 4.18Å; I267-W466 HydrophobicContact CD1-CB 3.52Å; I267-W466 HydrophobicContact CD1-CG 4.17Å
268A93.6Very high90.2Very high32 Ų3249.4 Ų49.426%0.26423%0.232SC..Hα-helixtrans-56-45.3175.400000112.3Q264 F265 V270 I271 F272Q264-A268 WeakPolarHBondContact O-CB 3.26Å; Q264-A268 PolarHBondContact O-N 3.26Å; F265-A268 PolarHBondContact O-N 3.17Å; A268-V270 PolarHBondContact O-N 2.96Å; A268-I271 PolarHBondContact O-N 2.82Å; A268-F272 WeakPolarHBondContact O-CB 3.5Å; A268-F272 PolarHBondContact O-N 3.31Å
269G93.8Very high90.7Very high30 Ų3042.2 Ų42.231%0.30921%0.209SC..Hα-helixtrans-62.2-40.5178.200000113.4F265 W266 I267 F272 L273F265-G269 PolarHBondContact O-N 3.01Å; W266-G269 PolarHBondContact O-N 3.4Å; I267-G269 VanDerWaalsContact C-N 3.32Å; I267-G269 PolarHBondContact O-N 2.95Å; G269-F272 PolarHBondContact O-N 3.09Å; G269-L273 WeakPolarHBondContact O-CB 3.39Å; G269-L273 WeakPolarHBondContact O-CG 3.4Å; G269-L273 PolarHBondContact O-N 3.49Å
270V95.1Very high91.4Very high3 Ų341.1 Ų41.12%0.01820%0.204CC..Hα-helixtrans-69.1-38.3176.3175.30000111.7W266 I267 A268 G274 K309 L312 A313 L316 F455 L459W266-V270 WeakPolarHBondContact O-CG2 3.32Å; W266-V270 PolarHBondContact O-N 3.35Å; I267-V270 PolarHBondContact O-N 3.37Å; A268-V270 PolarHBondContact O-N 2.96Å; V270-G274 PolarHBondContact O-N 3.45Å; V270-K309 HydrophobicContact CG1-CG 4.41Å; V270-L312 HydrophobicContact CG2-CB 4.06Å; V270-A313 HydrophobicContact CG1-CB 3.9Å; V270-A313 HydrophobicContact CG2-CB 4.44Å; V270-L316 HydrophobicContact CB-CD1 4.42Å; V270-L316 HydrophobicContact CG2-CD1 3.87Å; V270-F455 HydrophobicContact CG1-CZ 4.22Å; V270-L459 HydrophobicContact CB-CD1 4.48Å; V270-L459 HydrophobicContact CG1-CD1 3.7Å
271I95.6Very high91.8Very high3 Ų340.5 Ų40.52%0.01520%0.2CC..Hα-helixtrans-63.3-47.9173.9-66.1164.2000110.3A246 W249 I267 A268 G274 M275 L459 M463A246-I271 HydrophobicContact CB-CG2 3.97Å; W249-I271 HydrophobicContact CB-CD1 3.87Å; W249-I271 HydrophobicContact CD2-CD1 4.02Å; W249-I271 HydrophobicContact CG-CD1 3.72Å; I267-I271 HydrophobicContact CG2-CD1 3.79Å; I267-I271 HydrophobicContact CG2-CG1 4.45Å; I267-I271 WeakPolarHBondContact O-CG1 3.44Å; I267-I271 PolarHBondContact O-N 3.44Å; A268-I271 PolarHBondContact O-N 2.82Å; I271-G274 PolarHBondContact O-N 3.39Å; I271-M275 PolarHBondContact O-N 2.92Å; I271-L459 HydrophobicContact CG1-CD1 4.48Å; I271-L459 HydrophobicContact CG1-CD2 4.08Å; I271-L459 HydrophobicContact CG1-CG 4.44Å; I271-M463 HydrophobicContact CD1-CG 4.13Å; I271-M463 HydrophobicContact CD1-SD 3.77Å
272F95.6Very high92.3Very high117 Ų11740.1 Ų40.151%0.51320%0.199SC..Hα-helixtrans-61-46.6178.5175.9-100.8000112.2A268 G269 G274 M275 V276A268-F272 WeakPolarHBondContact O-CB 3.5Å; A268-F272 PolarHBondContact O-N 3.31Å; G269-F272 PolarHBondContact O-N 3.09Å; F272-G274 VanDerWaalsContact C-N 3.3Å; F272-G274 PolarHBondContact O-N 3.03Å; F272-M275 HydrophobicContact CD2-CE 3.78Å; F272-M275 HydrophobicContact CE2-CE 3.83Å; F272-M275 WeakPolarHBondContact O-CB 3.45Å; F272-M275 PolarHBondContact O-N 3.43Å; F272-V276 HydrophobicContact CD1-CG2 4.4Å; F272-V276 HydrophobicContact CE1-CG2 3.92Å; F272-V276 HydrophobicContact CE2-CG2 4.11Å; F272-V276 HydrophobicContact CZ-CG2 3.76Å; F272-V276 WeakPolarHBondContact O-CG2 3.3Å; F272-V276 PolarHBondContact O-N 3.41Å
273L94.6Very high92.6Very high25 Ų2533.2 Ų33.213%0.13118%0.183CC..Hα-helixtrans-62.5-36.6175.5-76.5167.7000112.3G269 V276 E277 L305 L308 K309 L312G269-L273 WeakPolarHBondContact O-CB 3.39Å; G269-L273 WeakPolarHBondContact O-CG 3.4Å; G269-L273 PolarHBondContact O-N 3.49Å; L273-V276 PolarHBondContact O-N 2.87Å; L273-E277 VanDerWaalsContact O-CB 3.27Å; L273-E277 WeakPolarHBondContact O-CB 3.26Å; L273-E277 PolarHBondContact O-N 2.97Å; L273-L305 HydrophobicContact CD2-CD2 3.94Å; L273-L308 HydrophobicContact CD1-CG 4.44Å; L273-L308 HydrophobicContact CD2-CD2 4.32Å; L273-K309 HydrophobicContact CB-CB 4.05Å; L273-K309 HydrophobicContact CB-CG 3.97Å; L273-L312 HydrophobicContact CD1-CD1 3.31Å
274G94.3Very high92.9Very high0 Ų033.1 Ų33.10%018%0.182CC..Hα-helixtrans-64.1-40.4172.800000113.1V270 I271 F272 E277 K278V270-G274 PolarHBondContact O-N 3.45Å; I271-G274 PolarHBondContact O-N 3.39Å; F272-G274 VanDerWaalsContact C-N 3.3Å; F272-G274 PolarHBondContact O-N 3.03Å; G274-E277 PolarHBondContact O-N 3.5Å; G274-K278 WeakPolarHBondContact O-CG 3.46Å; G274-K278 PolarHBondContact O-N 3.28Å
275M94.9Very high92.9Very high51 Ų5134.2 Ų34.225%0.25119%0.186SC..Hα-helixtrans-62-47.2173.8-176.3-170.973.800111.5I243 A246 I271 F272 K278 A279I243-M275 HydrophobicContact CG1-CG 4.18Å; I243-M275 HydrophobicContact CG1-SD 4.27Å; A246-M275 HydrophobicContact CB-SD 4.28Å; I271-M275 PolarHBondContact O-N 2.92Å; F272-M275 HydrophobicContact CD2-CE 3.78Å; F272-M275 HydrophobicContact CE2-CE 3.83Å; F272-M275 WeakPolarHBondContact O-CB 3.45Å; F272-M275 PolarHBondContact O-N 3.43Å; M275-K278 PolarHBondContact O-N 3.3Å; M275-A279 WeakPolarHBondContact O-CB 3.12Å; M275-A279 PolarHBondContact O-N 2.99Å
276V95.6Very high92.9Very high39 Ų3934.9 Ų34.924%0.23619%0.191CC..Hα-helixtrans-64.5-43.5178176.20000111.4F272 L273 K278 A279 L280 L305F272-V276 HydrophobicContact CD1-CG2 4.4Å; F272-V276 HydrophobicContact CE1-CG2 3.92Å; F272-V276 HydrophobicContact CE2-CG2 4.11Å; F272-V276 HydrophobicContact CZ-CG2 3.76Å; F272-V276 WeakPolarHBondContact O-CG2 3.3Å; F272-V276 PolarHBondContact O-N 3.41Å; L273-V276 PolarHBondContact O-N 2.87Å; V276-K278 PolarHBondContact O-N 3.49Å; V276-A279 PolarHBondContact O-N 3.26Å; V276-L280 HydrophobicContact CG1-CD1 3.88Å; V276-L280 HydrophobicContact CG1-CG 4.35Å; V276-L280 VanDerWaalsContact O-CG 3.31Å; V276-L280 WeakPolarHBondContact O-CG 3.42Å; V276-L280 PolarHBondContact O-N 3.21Å; V276-L305 HydrophobicContact CG1-CD1 4.02Å
277E94.3Very high92.9Very high1 Ų131.8 Ų31.81%0.00518%0.184CC..Hα-helixtrans-55.6-49.4174.9-176.2-143.9135.900111.3L273 G274 L280 F281 K309L273-E277 VanDerWaalsContact O-CB 3.27Å; L273-E277 WeakPolarHBondContact O-CB 3.26Å; L273-E277 PolarHBondContact O-N 2.97Å; G274-E277 PolarHBondContact O-N 3.5Å; E277-L280 PolarHBondContact O-N 3.08Å; E277-F281 HydrophobicContact CG-CD2 3.92Å; E277-F281 HydrophobicContact CG-CE2 3.76Å; E277-F281 VanDerWaalsContact O-CD2 3.27Å; E277-F281 WeakPolarHBondContact O-CD2 3.33Å; E277-F281 PolarHBondContact O-N 2.64Å; E277-F281 VanDerWaalsContact O-N 3.08Å; E277-K309 IonicContact OE1-NZ 3.38Å; E277-K309 WeakPolarHBondContact OE2-CD 3.42Å; E277-K309 WeakPolarHBondContact OE2-CE 3.23Å; E277-K309 IonicContact OE2-NZ 3.34Å; E277-K309 PolarHBondContact OE2-NZ 3.27Å
278K92.8Very high92.7Very high1 Ų131.8 Ų31.80%0.00418%0.184CC..Hα-helixtrans-67.9-37.3179.9-62.1-53.3170.8-154.30112.7Y235 M238 C239 Y242 G274 M275 V276 C282Y235-K278 HydrophobicContact CD1-CD 3.62Å; Y235-K278 HydrophobicContact CE1-CD 3.84Å; M238-K278 HydrophobicContact CB-CD 4.37Å; M238-K278 HydrophobicContact CB-CG 4.49Å; C239-K278 HydrophobicContact CB-CB 3.9Å; Y242-K278 HydrophobicContact CD2-CG 4Å; Y242-K278 HydrophobicContact CE2-CG 4.39Å; G274-K278 WeakPolarHBondContact O-CG 3.46Å; G274-K278 PolarHBondContact O-N 3.28Å; M275-K278 PolarHBondContact O-N 3.3Å; V276-K278 PolarHBondContact O-N 3.49Å; K278-C282 WeakPolarHBondContact O-CB 3.35Å; K278-C282 PolarHBondContact O-N 3.4Å; K278-C282 PolarHBondContact O-SG 3.11Å
279A94Very high92.5Very high46 Ų4631.8 Ų31.838%0.3818%0.179SC..Hα-helixtrans-61.8-42.6174.300000112.2M275 V276 C282 A283M275-A279 WeakPolarHBondContact O-CB 3.12Å; M275-A279 PolarHBondContact O-N 2.99Å; V276-A279 PolarHBondContact O-N 3.26Å; A279-C282 PolarHBondContact O-N 3.49Å; A279-A283 WeakPolarHBondContact O-CB 3.43Å; A279-A283 PolarHBondContact O-N 2.95Å
280L93.4Very high92.3Very high27 Ų2735.2 Ų35.214%0.14119%0.194CC..Hα-helixtrans-66.5-44.2178.7-70.4168.6000112.6V276 E277 A283 E284 L298 F301 A302 L305V276-L280 HydrophobicContact CG1-CD1 3.88Å; V276-L280 HydrophobicContact CG1-CG 4.35Å; V276-L280 VanDerWaalsContact O-CG 3.31Å; V276-L280 WeakPolarHBondContact O-CG 3.42Å; V276-L280 PolarHBondContact O-N 3.21Å; E277-L280 PolarHBondContact O-N 3.08Å; L280-A283 PolarHBondContact O-N 3.29Å; L280-E284 WeakPolarHBondContact O-CB 3.35Å; L280-E284 PolarHBondContact O-N 3.4Å; L280-L298 HydrophobicContact CD2-CD1 3.73Å; L280-F301 HydrophobicContact CD1-CD1 3.9Å; L280-F301 HydrophobicContact CD1-CE1 3.85Å; L280-F301 HydrophobicContact CD2-CD1 4.32Å; L280-F301 HydrophobicContact CD2-CE1 4.39Å; L280-A302 HydrophobicContact CB-CB 3.9Å; L280-A302 HydrophobicContact CD1-CB 4.44Å; L280-L305 HydrophobicContact CD1-CD1 3.29Å
281F90.9Very high92Very high10 Ų1038.2 Ų38.24%0.04421%0.212CC..Hα-helixtrans-64-40.3174.2-78.3-64.6000112Y235 E277 A283 E284 Y285 L299 A302Y235-F281 HydrophobicContact CD1-CB 3.52Å; Y235-F281 HydrophobicContact CD1-CD2 4.37Å; Y235-F281 HydrophobicContact CD1-CG 4.17Å; Y235-F281 HydrophobicContact CD2-CB 4.46Å; Y235-F281 HydrophobicContact CE1-CB 3.43Å; Y235-F281 VanDerWaalsContact CE1-CB 3.43Å; Y235-F281 HydrophobicContact CE1-CD1 4.4Å; Y235-F281 AromaticContact CE1-CD2 3.54Å; Y235-F281 HydrophobicContact CE1-CD2 3.54Å; Y235-F281 HydrophobicContact CE1-CE2 4.4Å; Y235-F281 AromaticContact CE1-CG 3.54Å; Y235-F281 HydrophobicContact CE1-CG 3.54Å; Y235-F281 HydrophobicContact CE2-CB 4.41Å; Y235-F281 HydrophobicContact CG-CB 4.06Å; Y235-F281 AromaticContact CZ-CD2 4Å; Y235-F281 AromaticContact CZ-CG 3.77Å; E277-F281 HydrophobicContact CG-CD2 3.92Å; E277-F281 HydrophobicContact CG-CE2 3.76Å; E277-F281 VanDerWaalsContact O-CD2 3.27Å; E277-F281 WeakPolarHBondContact O-CD2 3.33Å; E277-F281 PolarHBondContact O-N 2.64Å; E277-F281 VanDerWaalsContact O-N 3.08Å; F281-A283 PolarHBondContact O-N 3.03Å; F281-E284 PolarHBondContact O-N 3.45Å; F281-Y285 WeakPolarHBondContact O-CD2 3.43Å; F281-Y285 PolarHBondContact O-N 3.3Å; F281-L299 HydrophobicContact CE1-CD1 4.24Å; F281-A302 HydrophobicContact CE1-CB 4.28Å; F281-A302 HydrophobicContact CE2-CB 4.48Å; F281-A302 HydrophobicContact CZ-CB 4.24Å
282C90.6Very high91.4Very high21 Ų2138 Ų3814%0.14221%0.211CC..Hα-helixtrans-58.3-48.7173.8-67.40000111.5Y235 K278 A279 E284 Y285 E286Y235-C282 PolarHBondContact O-SG 2.93Å; K278-C282 WeakPolarHBondContact O-CB 3.35Å; K278-C282 PolarHBondContact O-N 3.4Å; K278-C282 PolarHBondContact O-SG 3.11Å; A279-C282 PolarHBondContact O-N 3.49Å; C282-E284 VanDerWaalsContact C-N 3.33Å; C282-E284 PolarHBondContact O-N 3.33Å; C282-Y285 PolarHBondContact O-N 3.26Å; C282-E286 WeakPolarHBondContact O-CB 3.32Å; C282-E286 PolarHBondContact O-N 2.98Å
283A91.3Very high90.8Very high45 Ų4534.6 Ų34.637%0.37220%0.202SC..Hα-helixtrans-61.4-39.5179.500000112.4A279 L280 F281 N287A279-A283 WeakPolarHBondContact O-CB 3.43Å; A279-A283 PolarHBondContact O-N 2.95Å; L280-A283 PolarHBondContact O-N 3.29Å; F281-A283 PolarHBondContact O-N 3.03Å; A283-N287 WeakPolarHBondContact O-CB 3.39Å; A283-N287 PolarHBondContact O-N 3.39Å
284E90.1Very high90.2Very high3 Ų334 Ų341%0.01420%0.201CC..Hα-helixtrans-71.9-38.2178.8179.963.1176.900112.7L280 F281 C282 T288 A294 S295 L298 L299L280-E284 WeakPolarHBondContact O-CB 3.35Å; L280-E284 PolarHBondContact O-N 3.4Å; F281-E284 PolarHBondContact O-N 3.45Å; C282-E284 VanDerWaalsContact C-N 3.33Å; C282-E284 PolarHBondContact O-N 3.33Å; E284-T288 VanDerWaalsContact O-CB 3.27Å; E284-T288 WeakPolarHBondContact O-CB 3.4Å; E284-T288 PolarHBondContact O-N 3Å; E284-T288 PolarHBondContact O-OG1 3.49Å; E284-A294 VanDerWaalsContact OE1-CA 3.29Å; E284-A294 WeakPolarHBondContact OE1-CA 3.48Å; E284-A294 VanDerWaalsContact OE1-CB 3.3Å; E284-A294 WeakPolarHBondContact OE1-CB 3.17Å; E284-S295 PolarHBondContact OE1-N 3.37Å; E284-S295 PolarHBondContact OE2-N 3.36Å; E284-S295 PolarHBondContact OE2-OG 2.96Å; E284-L298 HydrophobicContact CB-CD2 4.18Å; E284-L299 HydrophobicContact CG-CD1 4.37Å
285Y88.6Confident89.8Confident26 Ų2635.8 Ų35.810%0.10221%0.213CC..Hα-helixtrans-66.8-40.4172.4-80-67.3000112.2P39 I224 E228 L231 M232 Y235 F281 C282 T288 N289P39-Y285 HydrophobicContact CB-CE1 4.05Å; I224-Y285 HydrophobicContact CD1-CD1 4.41Å; E228-Y285 HydrophobicContact CB-CE1 4.15Å; E228-Y285 HydrophobicContact CG-CE1 4.16Å; L231-Y285 VanDerWaalsContact CD2-OH 3.28Å; L231-Y285 WeakPolarHBondContact CD2-OH 3.48Å; M232-Y285 HydrophobicContact CB-CG 4.27Å; M232-Y285 HydrophobicContact CG-CG 4.49Å; Y235-Y285 AromaticContact CD2-CD2 3.95Å; Y235-Y285 HydrophobicContact CD2-CD2 3.95Å; Y235-Y285 AromaticContact CD2-CE2 3.54Å; Y235-Y285 HydrophobicContact CD2-CE2 3.54Å; Y235-Y285 HydrophobicContact CE2-CD2 4.35Å; Y235-Y285 AromaticContact CE2-CE2 3.51Å; Y235-Y285 HydrophobicContact CE2-CE2 3.51Å; Y235-Y285 HydrophobicContact CG-CE2 4.47Å; F281-Y285 WeakPolarHBondContact O-CD2 3.43Å; F281-Y285 PolarHBondContact O-N 3.3Å; C282-Y285 PolarHBondContact O-N 3.26Å; Y285-T288 PolarHBondContact O-N 3.02Å; Y285-N289 WeakPolarHBondContact O-CB 3.46Å; Y285-N289 PolarHBondContact O-N 3.47Å
286E89.5Confident89.2Confident130 Ų13036.2 Ų36.261%0.60722%0.219SC*.Hα-helixtrans-65.5-46.8175.9-174.7172.3-163.400111.4C282 T288 N289 V290C282-E286 WeakPolarHBondContact O-CB 3.32Å; C282-E286 PolarHBondContact O-N 2.98Å; E286-T288 PolarHBondContact O-N 3.05Å; E286-N289 PolarHBondContact O-N 3.08Å; E286-N289 VanDerWaalsContact O-N 3.14Å; E286-V290 WeakPolarHBondContact O-CG2 3.41Å; E286-V290 PolarHBondContact O-N 2.84Å
287N89.8Confident88.7Confident57 Ų5736.9 Ų36.931%0.30524%0.235SC..Hα-helixtrans-57.5-47.4174.2178.454.3000111.5A283 N289 V290 V291A283-N287 WeakPolarHBondContact O-CB 3.39Å; A283-N287 PolarHBondContact O-N 3.39Å; N287-N289 VanDerWaalsContact C-N 3.3Å; N287-N289 PolarHBondContact O-N 3.38Å; N287-V290 PolarHBondContact O-N 3.42Å; N287-V291 WeakPolarHBondContact O-CB 3.45Å; N287-V291 WeakPolarHBondContact O-CG2 3.4Å; N287-V291 PolarHBondContact O-N 3.01Å; N287-V291 WeakPolarHBondContact OD1-CG2 3.36Å
288T87.6Confident88.3Confident1 Ų139.3 Ų39.31%0.00625%0.247CC..Hα-helixtrans-60.5-39.9175.7-58.10000111.4P39 E284 Y285 E286 V290 G292P39-T288 HydrophobicContact CB-CG2 4.39Å; P39-T288 HydrophobicContact CG-CG2 4.28Å; E284-T288 VanDerWaalsContact O-CB 3.27Å; E284-T288 WeakPolarHBondContact O-CB 3.4Å; E284-T288 PolarHBondContact O-N 3Å; E284-T288 PolarHBondContact O-OG1 3.49Å; Y285-T288 PolarHBondContact O-N 3.02Å; E286-T288 PolarHBondContact O-N 3.05Å; T288-V290 VanDerWaalsContact C-N 3.33Å; T288-V290 PolarHBondContact O-N 2.82Å; T288-G292 VanDerWaalsContact O-CA 3.27Å; T288-G292 WeakPolarHBondContact O-CA 3.37Å; T288-G292 PolarHBondContact O-N 3.44Å
289N90.9Very high88Confident31 Ų3140 Ų4017%0.16625%0.251CS..Hα-helixtrans-70.2-26.1179.4-167.134.7000114H221 G222 Y223 I224 Y285 E286 N287H221-N289 PolarHBondContact O-ND2 3.46Å; H221-N289 PolarHBondContact O-OD1 3.16Å; H221-N289 VanDerWaalsContact O-OD1 3.05Å; G222-N289 VanDerWaalsContact CA-OD1 3.3Å; G222-N289 WeakPolarHBondContact CA-OD1 3.27Å; Y223-N289 WeakPolarHBondContact CD2-O 3.11Å; Y223-N289 PolarHBondContact N-O 3.34Å; Y223-N289 VanDerWaalsContact N-O 3.16Å; Y223-N289 PolarHBondContact N-OD1 2.9Å; I224-N289 HydrophobicContact CB-CB 4.13Å; I224-N289 WeakPolarHBondContact CB-OD1 3.16Å; I224-N289 WeakPolarHBondContact CG2-OD1 3.3Å; I224-N289 PolarHBondContact N-OD1 3.42Å; Y285-N289 WeakPolarHBondContact O-CB 3.46Å; Y285-N289 PolarHBondContact O-N 3.47Å; E286-N289 PolarHBondContact O-N 3.08Å; E286-N289 VanDerWaalsContact O-N 3.14Å; N287-N289 VanDerWaalsContact C-N 3.3Å; N287-N289 PolarHBondContact O-N 3.38Å
290V89Confident87.7Confident102 Ų10239.8 Ų39.862%0.61824%0.243SC*.Hα-helixtrans-90-45.5178.3173.80000112.2Y223 E286 N287 T288Y223-V290 WeakPolarHBondContact CE2-O 3.29Å; E286-V290 WeakPolarHBondContact O-CG2 3.41Å; E286-V290 PolarHBondContact O-N 2.84Å; N287-V290 PolarHBondContact O-N 3.42Å; T288-V290 VanDerWaalsContact C-N 3.33Å; T288-V290 PolarHBondContact O-N 2.82Å
291V88.1Confident87.6Confident66 Ų6643.5 Ų43.540%0.426%0.258SS..Hα-helixtrans-88.6-29.4-173.1-178.50000112.3N287N287-V291 WeakPolarHBondContact O-CB 3.45Å; N287-V291 WeakPolarHBondContact O-CG2 3.4Å; N287-V291 PolarHBondContact O-N 3.01Å; N287-V291 WeakPolarHBondContact OD1-CG2 3.36Å
292G82.7Confident87.6Confident0 Ų043 Ų430%026%0.256CS..SBendtrans85.83.9-17700000115.4G42 L43 Y223 T288G42-G292 PolarHBondContact N-O 3.46Å; L43-G292 PolarHBondContact N-O 2.83Å; Y223-G292 VanDerWaalsContact CB-CA 3.48Å; T288-G292 VanDerWaalsContact O-CA 3.27Å; T288-G292 WeakPolarHBondContact O-CA 3.37Å; T288-G292 PolarHBondContact O-N 3.44Å
293S83.6Confident87.6Confident44 Ų4442.4 Ų42.431%0.30825%0.251SS..SBendtrans-143.1134.6174.258.90000110.6
294A82.4Confident87.6Confident14 Ų1443.3 Ų43.312%0.11625%0.249CC..  trans-58.7153.9169.200000111.8S38 P39 E284 P296S38-A294 VanDerWaalsContact OG-CB 3.28Å; S38-A294 WeakPolarHBondContact OG-CB 3.45Å; P39-A294 HydrophobicContact CG-CB 4.04Å; E284-A294 VanDerWaalsContact OE1-CA 3.29Å; E284-A294 WeakPolarHBondContact OE1-CA 3.48Å; E284-A294 VanDerWaalsContact OE1-CB 3.3Å; E284-A294 WeakPolarHBondContact OE1-CB 3.17Å; A294-P296 WeakPolarHBondContact O-CD 3.48Å
295S85.3Confident87.8Confident36 Ų3644.3 Ų44.325%0.25226%0.255SS..  trans-103.4105.3176.169.80000110.6E284 G297 L298 L299E284-S295 PolarHBondContact OE1-N 3.37Å; E284-S295 PolarHBondContact OE2-N 3.36Å; E284-S295 PolarHBondContact OE2-OG 2.96Å; S295-G297 VanDerWaalsContact C-N 3.3Å; S295-G297 PolarHBondContact O-N 2.73Å; S295-G297 VanDerWaalsContact O-N 3.12Å; S295-L298 PolarHBondContact O-N 3.23Å; S295-L298 WeakPolarHBondContact OG-CB 3.49Å; S295-L299 PolarHBondContact O-N 3.2Å; S295-L299 VanDerWaalsContact O-N 3.14Å
296P82.6Confident87.9Confident60 Ų6043.6 Ų43.639%0.3925%0.254SS..Hα-helixtrans-54-42.2-168.2-30.936.8000114.3T35 A294 I300T35-P296 HydrophobicContact CG2-CB 3.92Å; T35-P296 HydrophobicContact CG2-CG 4.46Å; A294-P296 WeakPolarHBondContact O-CD 3.48Å; P296-I300 WeakPolarHBondContact O-CB 3.35Å; P296-I300 WeakPolarHBondContact O-CD1 3.24Å; P296-I300 VanDerWaalsContact O-CG1 3.24Å; P296-I300 WeakPolarHBondContact O-CG1 3.46Å; P296-I300 PolarHBondContact O-N 2.91Å
297G85Confident88.1Confident54 Ų5437.4 Ų37.456%0.55723%0.225SC*.Hα-helixtrans-66.7-37.6-179.800000114S295 F301S295-G297 VanDerWaalsContact C-N 3.3Å; S295-G297 PolarHBondContact O-N 2.73Å; S295-G297 VanDerWaalsContact O-N 3.12Å; G297-F301 VanDerWaalsContact O-CB 3.29Å; G297-F301 WeakPolarHBondContact O-CB 3.44Å; G297-F301 PolarHBondContact O-N 2.93Å; G297-F301 VanDerWaalsContact O-N 3.08Å
298L85.8Confident88.4Confident52 Ų5237.5 Ų37.527%0.27223%0.225SC..Hα-helixtrans-71.7-40.9178.8-169.961.3000110.6L280 E284 S295 F301 A302L280-L298 HydrophobicContact CD2-CD1 3.73Å; E284-L298 HydrophobicContact CB-CD2 4.18Å; S295-L298 PolarHBondContact O-N 3.23Å; S295-L298 WeakPolarHBondContact OG-CB 3.49Å; L298-F301 PolarHBondContact O-N 3.44Å; L298-A302 WeakPolarHBondContact O-CB 3.24Å; L298-A302 PolarHBondContact O-N 3.36Å
299L86.3Confident88.7Confident14 Ų1437.9 Ų37.97%0.07323%0.226CC..Hα-helixtrans-65.2-45178.3-174.261.7000112.1S38 F281 E284 S295 F301 A302 E303 I357S38-L299 WeakPolarHBondContact OG-CD2 3.43Å; F281-L299 HydrophobicContact CE1-CD1 4.24Å; E284-L299 HydrophobicContact CG-CD1 4.37Å; S295-L299 PolarHBondContact O-N 3.2Å; S295-L299 VanDerWaalsContact O-N 3.14Å; L299-F301 VanDerWaalsContact C-N 3.33Å; L299-F301 PolarHBondContact O-N 3.36Å; L299-A302 PolarHBondContact O-N 2.69Å; L299-E303 PolarHBondContact O-N 3.4Å; L299-I357 HydrophobicContact CD2-CD1 4.49Å; L299-I357 HydrophobicContact CD2-CG1 4.16Å; L299-I357 HydrophobicContact CD2-CG2 3.7Å; L299-I357 HydrophobicContact CG-CD1 3.89Å; L299-I357 HydrophobicContact CG-CG1 4.08Å; L299-I357 HydrophobicContact CG-CG2 4.1Å
300I88.3Confident88.8Confident42 Ų4239 Ų3922%0.21523%0.228CC..Hα-helixtrans-60.7-42.6174-69.5166000110.9P296 E303 L304 V354 I357P296-I300 WeakPolarHBondContact O-CB 3.35Å; P296-I300 WeakPolarHBondContact O-CD1 3.24Å; P296-I300 VanDerWaalsContact O-CG1 3.24Å; P296-I300 WeakPolarHBondContact O-CG1 3.46Å; P296-I300 PolarHBondContact O-N 2.91Å; I300-E303 PolarHBondContact O-N 3.19Å; I300-L304 WeakPolarHBondContact O-CB 3.41Å; I300-L304 PolarHBondContact O-N 3.23Å; I300-V354 HydrophobicContact CG2-CG2 4.44Å; I300-I357 HydrophobicContact CG1-CG2 4.28Å
301F90.6Very high89Confident106 Ų10634.4 Ų34.447%0.46520%0.201SC..Hα-helixtrans-66.6-42.3178.2-179.9-112.1000112.9L280 G297 L298 L299 E303 L304 L305L280-F301 HydrophobicContact CD1-CD1 3.9Å; L280-F301 HydrophobicContact CD1-CE1 3.85Å; L280-F301 HydrophobicContact CD2-CD1 4.32Å; L280-F301 HydrophobicContact CD2-CE1 4.39Å; G297-F301 VanDerWaalsContact O-CB 3.29Å; G297-F301 WeakPolarHBondContact O-CB 3.44Å; G297-F301 PolarHBondContact O-N 2.93Å; G297-F301 VanDerWaalsContact O-N 3.08Å; L298-F301 PolarHBondContact O-N 3.44Å; L299-F301 VanDerWaalsContact C-N 3.33Å; L299-F301 PolarHBondContact O-N 3.36Å; F301-E303 VanDerWaalsContact C-N 3.32Å; F301-E303 PolarHBondContact O-N 3.36Å; F301-L304 PolarHBondContact O-N 2.88Å; F301-L305 HydrophobicContact CD1-CD1 3.97Å; F301-L305 HydrophobicContact CE1-CD1 3.44Å; F301-L305 VanDerWaalsContact CE1-CD1 3.44Å; F301-L305 HydrophobicContact CE2-CD1 4.08Å; F301-L305 HydrophobicContact CE2-CG 4.38Å; F301-L305 HydrophobicContact CZ-CD1 3.51Å; F301-L305 HydrophobicContact CZ-CG 4.25Å; F301-L305 PolarHBondContact O-N 2.91Å
302A90.9Very high89.3Confident0 Ų033.1 Ų33.10%019%0.191CC..Hα-helixtrans-60.6-41.6175.300000111.7L280 F281 L298 L299 L305 S306L280-A302 HydrophobicContact CB-CB 3.9Å; L280-A302 HydrophobicContact CD1-CB 4.44Å; F281-A302 HydrophobicContact CE1-CB 4.28Å; F281-A302 HydrophobicContact CE2-CB 4.48Å; F281-A302 HydrophobicContact CZ-CB 4.24Å; L298-A302 WeakPolarHBondContact O-CB 3.24Å; L298-A302 PolarHBondContact O-N 3.36Å; L299-A302 PolarHBondContact O-N 2.69Å; A302-L305 PolarHBondContact O-N 3.03Å; A302-S306 WeakPolarHBondContact O-CB 3.28Å; A302-S306 PolarHBondContact O-N 2.88Å
303E90.5Very high89.8Confident7 Ų733.6 Ų33.63%0.03320%0.195CC..Hα-helixtrans-71.8-37.6178.1-169.162-159.900112.7L299 I300 F301 L305 S306 A307 R356 I357L299-E303 PolarHBondContact O-N 3.4Å; I300-E303 PolarHBondContact O-N 3.19Å; F301-E303 VanDerWaalsContact C-N 3.32Å; F301-E303 PolarHBondContact O-N 3.36Å; E303-L305 VanDerWaalsContact C-N 3.3Å; E303-L305 PolarHBondContact O-N 2.91Å; E303-S306 CarbonylContact O-C 3.46Å; E303-S306 WeakPolarHBondContact O-CB 3.47Å; E303-S306 PolarHBondContact O-N 2.89Å; E303-S306 VanDerWaalsContact O-N 3.16Å; E303-A307 WeakPolarHBondContact O-CB 3.25Å; E303-A307 PolarHBondContact O-N 3.33Å; E303-R356 IonicContact OE1-CZ 3.48Å; E303-R356 VanDerWaalsContact OE1-CZ 3.3Å; E303-R356 IonicContact OE1-NH1 2.58Å; E303-R356 PolarHBondContact OE1-NH1 3.49Å; E303-R356 IonicContact OE1-NH2 2.61Å; E303-R356 PolarHBondContact OE1-NH2 3.02Å; E303-R356 IonicContact OE2-CZ 3.79Å; E303-R356 IonicContact OE2-NH2 2.68Å; E303-R356 PolarHBondContact OE2-NH2 3.42Å; E303-I357 HydrophobicContact CB-CD1 3.49Å; E303-I357 VanDerWaalsContact CB-CD1 3.49Å; E303-I357 HydrophobicContact CG-CD1 3.84Å
304L92Very high90.2Very high65 Ų6534.4 Ų34.434%0.3419%0.191SC..Hα-helixtrans-62.1-38.7173.3-172.865.7000111.6I300 F301 A307 L308 F346 S350I300-L304 WeakPolarHBondContact O-CB 3.41Å; I300-L304 PolarHBondContact O-N 3.23Å; F301-L304 PolarHBondContact O-N 2.88Å; L304-A307 PolarHBondContact O-N 3.47Å; L304-L308 WeakPolarHBondContact O-CB 3.46Å; L304-L308 PolarHBondContact O-N 3.33Å; L304-F346 HydrophobicContact CD1-CE2 4.06Å; L304-F346 HydrophobicContact CD1-CZ 3.67Å; L304-F346 HydrophobicContact CG-CZ 4.36Å; L304-S350 WeakPolarHBondContact CD1-OG 3.39Å
305L94Very high90.6Very high24 Ų2434.8 Ų34.813%0.12619%0.191CC..Hα-helixtrans-68.5-37.8172.6-78.3170.5000112.5L273 V276 L280 F301 A302 E303 L308 K309L273-L305 HydrophobicContact CD2-CD2 3.94Å; V276-L305 HydrophobicContact CG1-CD1 4.02Å; L280-L305 HydrophobicContact CD1-CD1 3.29Å; F301-L305 HydrophobicContact CD1-CD1 3.97Å; F301-L305 HydrophobicContact CE1-CD1 3.44Å; F301-L305 VanDerWaalsContact CE1-CD1 3.44Å; F301-L305 HydrophobicContact CE2-CD1 4.08Å; F301-L305 HydrophobicContact CE2-CG 4.38Å; F301-L305 HydrophobicContact CZ-CD1 3.51Å; F301-L305 HydrophobicContact CZ-CG 4.25Å; F301-L305 PolarHBondContact O-N 2.91Å; A302-L305 PolarHBondContact O-N 3.03Å; E303-L305 VanDerWaalsContact C-N 3.3Å; E303-L305 PolarHBondContact O-N 2.91Å; L305-L308 HydrophobicContact CD2-CD2 4.39Å; L305-L308 PolarHBondContact O-N 3.38Å; L305-K309 WeakPolarHBondContact O-CB 3.36Å; L305-K309 PolarHBondContact O-N 2.96Å
306S92.1Very high90.9Very high11 Ų1133.3 Ų33.38%0.07718%0.18CC..Hα-helixtrans-59.7-46.5171.5-177.20000111.3A302 E303 K309 R310A302-S306 WeakPolarHBondContact O-CB 3.28Å; A302-S306 PolarHBondContact O-N 2.88Å; E303-S306 CarbonylContact O-C 3.46Å; E303-S306 WeakPolarHBondContact O-CB 3.47Å; E303-S306 PolarHBondContact O-N 2.89Å; E303-S306 VanDerWaalsContact O-N 3.16Å; S306-K309 PolarHBondContact O-N 3.26Å; S306-R310 WeakPolarHBondContact O-CB 3.43Å; S306-R310 VanDerWaalsContact O-CG 3.27Å; S306-R310 WeakPolarHBondContact O-CG 3.3Å; S306-R310 PolarHBondContact O-N 3.48Å
307A93.7Very high91.3Very high0 Ų031.4 Ų31.40%017%0.167CC..Hα-helixtrans-61.4-45.7174.700000112E303 L304 K309 R310 T311 F346 A349E303-A307 WeakPolarHBondContact O-CB 3.25Å; E303-A307 PolarHBondContact O-N 3.33Å; L304-A307 PolarHBondContact O-N 3.47Å; A307-K309 PolarHBondContact O-N 3.14Å; A307-R310 PolarHBondContact O-N 2.9Å; A307-T311 WeakPolarHBondContact O-CB 3.34Å; A307-T311 PolarHBondContact O-N 3.24Å; A307-T311 PolarHBondContact O-OG1 3.39Å; A307-F346 HydrophobicContact CB-CD2 4.37Å; A307-F346 HydrophobicContact CB-CE2 4.26Å; A307-A349 HydrophobicContact CB-CB 4.04Å
308L94.8Very high91.6Very high58 Ų5829 Ų2930%0.30414%0.142SC..Hα-helixtrans-59.5-46.9175.8179.160.3000111.4L273 L304 L305 T311 L312 F346L273-L308 HydrophobicContact CD1-CG 4.44Å; L273-L308 HydrophobicContact CD2-CD2 4.32Å; L304-L308 WeakPolarHBondContact O-CB 3.46Å; L304-L308 PolarHBondContact O-N 3.33Å; L305-L308 HydrophobicContact CD2-CD2 4.39Å; L305-L308 PolarHBondContact O-N 3.38Å; L308-T311 WeakPolarHBondContact O-CB 3.28Å; L308-T311 PolarHBondContact O-N 2.94Å; L308-L312 HydrophobicContact CD1-CD1 3.84Å; L308-L312 HydrophobicContact CD1-CG 4.15Å; L308-L312 HydrophobicContact CG-CD1 3.86Å; L308-L312 WeakPolarHBondContact O-CG 3.36Å; L308-L312 PolarHBondContact O-N 3Å; L308-F346 HydrophobicContact CB-CD2 4.38Å; L308-F346 HydrophobicContact CB-CE2 3.8Å; L308-F346 HydrophobicContact CD1-CD2 4.5Å; L308-F346 HydrophobicContact CD1-CE2 4.3Å
309K94.4Very high91.7Very high10 Ų1027.2 Ų27.24%0.04313%0.133CC..Hα-helixtrans-64.4-44.5177.4-173.7-141.364.6178.40112.1V270 L273 E277 L305 S306 A307 T311 L312 A313 F455V270-K309 HydrophobicContact CG1-CG 4.41Å; L273-K309 HydrophobicContact CB-CB 4.05Å; L273-K309 HydrophobicContact CB-CG 3.97Å; E277-K309 IonicContact OE1-NZ 3.38Å; E277-K309 WeakPolarHBondContact OE2-CD 3.42Å; E277-K309 WeakPolarHBondContact OE2-CE 3.23Å; E277-K309 IonicContact OE2-NZ 3.34Å; E277-K309 PolarHBondContact OE2-NZ 3.27Å; L305-K309 WeakPolarHBondContact O-CB 3.36Å; L305-K309 PolarHBondContact O-N 2.96Å; S306-K309 PolarHBondContact O-N 3.26Å; A307-K309 PolarHBondContact O-N 3.14Å; K309-T311 VanDerWaalsContact C-N 3.26Å; K309-T311 PolarHBondContact O-N 3.49Å; K309-L312 PolarHBondContact O-N 3.04Å; K309-A313 VanDerWaalsContact O-CB 3.28Å; K309-A313 WeakPolarHBondContact O-CB 3.48Å; K309-A313 PolarHBondContact O-N 3.44Å; K309-F455 HydrophobicContact CD-CE1 3.94Å; K309-F455 HydrophobicContact CD-CZ 4.02Å; K309-F455 HydrophobicContact CG-CZ 4.45Å
310R92.7Very high91.7Very high54 Ų5426.7 Ų26.720%0.20413%0.13CC..Hα-helixtrans-53.1-46.8172.8-76.8165.172.7-174.34.5110.1S306 A307 R314 Y345 E352S306-R310 WeakPolarHBondContact O-CB 3.43Å; S306-R310 VanDerWaalsContact O-CG 3.27Å; S306-R310 WeakPolarHBondContact O-CG 3.3Å; S306-R310 PolarHBondContact O-N 3.48Å; A307-R310 PolarHBondContact O-N 2.9Å; R310-R314 VanDerWaalsContact O-CD 3.25Å; R310-R314 WeakPolarHBondContact O-CD 3.27Å; R310-R314 VanDerWaalsContact O-CG 3.25Å; R310-R314 WeakPolarHBondContact O-CG 3.31Å; R310-R314 PolarHBondContact O-N 3.5Å; R310-Y345 HydrophobicContact CB-CE1 4.21Å; R310-Y345 PolarHBondContact NE-OH 3.21Å; R310-E352 IonicContact CZ-OE2 3.15Å; R310-E352 IonicContact NH1-OE2 2.92Å; R310-E352 PolarHBondContact NH1-OE2 3.4Å; R310-E352 IonicContact NH2-OE2 3.55Å; R310-E352 PolarHBondContact NH2-OE2 2.88Å
311T94.3Very high91.7Very high6 Ų624.7 Ų24.74%0.03712%0.119CC..Hα-helixtrans-60.9-56.8178.3-51.20000111.7A307 L308 K309 A313 R314 L315 G342 Y345 F346A307-T311 WeakPolarHBondContact O-CB 3.34Å; A307-T311 PolarHBondContact O-N 3.24Å; A307-T311 PolarHBondContact O-OG1 3.39Å; L308-T311 WeakPolarHBondContact O-CB 3.28Å; L308-T311 PolarHBondContact O-N 2.94Å; K309-T311 VanDerWaalsContact C-N 3.26Å; K309-T311 PolarHBondContact O-N 3.49Å; T311-A313 VanDerWaalsContact C-N 3.31Å; T311-A313 PolarHBondContact O-N 3.48Å; T311-R314 PolarHBondContact O-N 2.96Å; T311-R314 VanDerWaalsContact O-N 3.14Å; T311-L315 HydrophobicContact CG2-CD1 4.13Å; T311-L315 HydrophobicContact CG2-CG 4.47Å; T311-L315 WeakPolarHBondContact O-CG 3.35Å; T311-L315 PolarHBondContact O-N 3.13Å; T311-G342 VanDerWaalsContact CG2-O 3.22Å; T311-G342 WeakPolarHBondContact CG2-O 3.38Å; T311-Y345 HydrophobicContact CG2-CD1 4.03Å; T311-Y345 WeakPolarHBondContact OG1-CD1 3.21Å; T311-F346 HydrophobicContact CG2-CB 3.95Å; T311-F346 WeakPolarHBondContact OG1-CA 3.33Å
312L93.5Very high91.4Very high39 Ų3921 Ų2120%0.20410%0.104CC..Hα-helixtrans-62.9-37.2-174.9-70.4168.4000112.2W266 V270 L273 L308 K309 L315 L316W266-L312 HydrophobicContact CE3-CD2 4.28Å; W266-L312 HydrophobicContact CZ3-CD2 3.64Å; V270-L312 HydrophobicContact CG2-CB 4.06Å; L273-L312 HydrophobicContact CD1-CD1 3.31Å; L308-L312 HydrophobicContact CD1-CD1 3.84Å; L308-L312 HydrophobicContact CD1-CG 4.15Å; L308-L312 HydrophobicContact CG-CD1 3.86Å; L308-L312 WeakPolarHBondContact O-CG 3.36Å; L308-L312 PolarHBondContact O-N 3Å; K309-L312 PolarHBondContact O-N 3.04Å; L312-L315 PolarHBondContact O-N 3.33Å; L312-L316 VanDerWaalsContact O-CB 3.28Å; L312-L316 WeakPolarHBondContact O-CB 3.3Å; L312-L316 PolarHBondContact O-N 2.84Å
313A92.8Very high90.9Very high9 Ų921 Ų217%0.07410%0.104CC..Hα-helixtrans-65.3-38175.700000112.9V270 K309 T311 L316 V317 F455V270-A313 HydrophobicContact CG1-CB 3.9Å; V270-A313 HydrophobicContact CG2-CB 4.44Å; K309-A313 VanDerWaalsContact O-CB 3.28Å; K309-A313 WeakPolarHBondContact O-CB 3.48Å; K309-A313 PolarHBondContact O-N 3.44Å; T311-A313 VanDerWaalsContact C-N 3.31Å; T311-A313 PolarHBondContact O-N 3.48Å; A313-L316 WeakPolarHBondContact O-CB 3.37Å; A313-L316 PolarHBondContact O-N 3.45Å; A313-V317 WeakPolarHBondContact O-CG2 3.34Å; A313-V317 PolarHBondContact O-N 3.03Å; A313-F455 HydrophobicContact CB-CE2 3.43Å; A313-F455 VanDerWaalsContact CB-CE2 3.43Å; A313-F455 HydrophobicContact CB-CZ 3.55Å
314R91.9Very high90.1Very high62 Ų6222.5 Ų22.523%0.23411%0.11CC..Hα-helixtrans-69.7-43.3176-70.2162.4176.9-133.4-1.3111.6R310 T311 L316 V317 I318 Y345 D377R310-R314 VanDerWaalsContact O-CD 3.25Å; R310-R314 WeakPolarHBondContact O-CD 3.27Å; R310-R314 VanDerWaalsContact O-CG 3.25Å; R310-R314 WeakPolarHBondContact O-CG 3.31Å; R310-R314 PolarHBondContact O-N 3.5Å; T311-R314 PolarHBondContact O-N 2.96Å; T311-R314 VanDerWaalsContact O-N 3.14Å; R314-L316 VanDerWaalsContact C-N 3.29Å; R314-L316 PolarHBondContact O-N 3.14Å; R314-V317 PolarHBondContact O-N 3.47Å; R314-I318 VanDerWaalsContact O-CD1 3.28Å; R314-I318 WeakPolarHBondContact O-CD1 3.34Å; R314-I318 WeakPolarHBondContact O-CG1 3.44Å; R314-I318 PolarHBondContact O-N 2.86Å; R314-Y345 VanDerWaalsContact CZ-CZ 3.43Å; R314-Y345 PolarHBondContact NH1-OH 2.99Å; R314-Y345 PolarHBondContact NH2-OH 3.49Å; R314-D377 IonicContact CZ-OD1 3.85Å; R314-D377 IonicContact CZ-OD2 2.73Å; R314-D377 IonicContact NH1-OD1 2.77Å; R314-D377 PolarHBondContact NH1-OD1 3.5Å; R314-D377 IonicContact NH1-OD2 3.29Å; R314-D377 PolarHBondContact NH1-OD2 3.24Å; R314-D377 IonicContact NH2-OD1 2.7Å; R314-D377 IonicContact NH2-OD2 3.74Å; R314-D377 PolarHBondContact NH2-OD2 2.97Å
315L91.9Very high88.8Confident22 Ų2220.7 Ų20.712%0.11511%0.107CC..Hα-helixtrans-57.4-44.3172.2-67.6177.9000111.3T311 L312 I318 I319 V338T311-L315 HydrophobicContact CG2-CD1 4.13Å; T311-L315 HydrophobicContact CG2-CG 4.47Å; T311-L315 WeakPolarHBondContact O-CG 3.35Å; T311-L315 PolarHBondContact O-N 3.13Å; L312-L315 PolarHBondContact O-N 3.33Å; L315-I318 PolarHBondContact O-N 2.83Å; L315-I319 HydrophobicContact CB-CD1 4.49Å; L315-I319 VanDerWaalsContact O-CB 3.26Å; L315-I319 WeakPolarHBondContact O-CB 3.44Å; L315-I319 WeakPolarHBondContact O-CD1 3.35Å; L315-I319 WeakPolarHBondContact O-CG1 3.33Å; L315-I319 PolarHBondContact O-N 2.94Å; L315-V338 HydrophobicContact CD2-CG1 3.69Å; L315-V338 VanDerWaalsContact CD2-O 3.28Å; L315-V338 WeakPolarHBondContact CD2-O 3.42Å
316L90.7Very high87.3Confident5 Ų520.8 Ų20.83%0.02611%0.108CC..Hα-helixtrans-57.4-50.7175.4-172.1165.6000111.3W266 I267 V270 L312 A313 R314 I318 I319 V320 I462W266-L316 HydrophobicContact CB-CD1 4.22Å; I267-L316 HydrophobicContact CB-CD1 4.38Å; I267-L316 HydrophobicContact CG1-CD1 3.8Å; I267-L316 HydrophobicContact CG1-CD2 4.33Å; I267-L316 HydrophobicContact CG1-CG 4.45Å; V270-L316 HydrophobicContact CB-CD1 4.42Å; V270-L316 HydrophobicContact CG2-CD1 3.87Å; L312-L316 VanDerWaalsContact O-CB 3.28Å; L312-L316 WeakPolarHBondContact O-CB 3.3Å; L312-L316 PolarHBondContact O-N 2.84Å; A313-L316 WeakPolarHBondContact O-CB 3.37Å; A313-L316 PolarHBondContact O-N 3.45Å; R314-L316 VanDerWaalsContact C-N 3.29Å; R314-L316 PolarHBondContact O-N 3.14Å; L316-I318 PolarHBondContact O-N 3.46Å; L316-I319 PolarHBondContact O-N 3.01Å; L316-V320 HydrophobicContact CD2-CG2 4Å; L316-V320 WeakPolarHBondContact O-CB 3.42Å; L316-V320 VanDerWaalsContact O-CG2 3.29Å; L316-V320 WeakPolarHBondContact O-CG2 3.28Å; L316-V320 PolarHBondContact O-N 3.24Å; L316-I462 HydrophobicContact CD2-CG2 4.27Å
317V90.7Very high85.7Confident19 Ų1921.8 Ų21.812%0.11511%0.112CC..Hα-helixtrans-59.7-43.9178169.30000111.9A313 R314 V320 S321 I384 F410 I462A313-V317 WeakPolarHBondContact O-CG2 3.34Å; A313-V317 PolarHBondContact O-N 3.03Å; R314-V317 PolarHBondContact O-N 3.47Å; V317-V320 PolarHBondContact O-N 2.98Å; V317-S321 WeakPolarHBondContact O-CB 3.21Å; V317-S321 PolarHBondContact O-N 3.45Å; V317-S321 PolarHBondContact O-OG 3.41Å; V317-I384 HydrophobicContact CG1-CD1 3.67Å; V317-I384 HydrophobicContact CG1-CG1 4.01Å; V317-I384 HydrophobicContact CG1-CG2 3.93Å; V317-F410 HydrophobicContact CG1-CZ 4.18Å; V317-I462 HydrophobicContact CG2-CD1 4.02Å
318I91.1Very high84.1Confident3 Ų327.7 Ų27.72%0.01514%0.137CC..Hα-helixtrans-63.3-48.5177.5-63.9155.4000111R314 L315 L316 V320 S321 L322 V338 L380 I384R314-I318 VanDerWaalsContact O-CD1 3.28Å; R314-I318 WeakPolarHBondContact O-CD1 3.34Å; R314-I318 WeakPolarHBondContact O-CG1 3.44Å; R314-I318 PolarHBondContact O-N 2.86Å; L315-I318 PolarHBondContact O-N 2.83Å; L316-I318 PolarHBondContact O-N 3.46Å; I318-V320 VanDerWaalsContact C-N 3.28Å; I318-V320 PolarHBondContact O-N 2.88Å; I318-S321 PolarHBondContact O-N 3.43Å; I318-L322 HydrophobicContact CG2-CD1 3.76Å; I318-L322 HydrophobicContact CG2-CG 4.41Å; I318-L322 WeakPolarHBondContact O-CB 3.36Å; I318-L322 VanDerWaalsContact O-CG 3.3Å; I318-L322 WeakPolarHBondContact O-CG 3.28Å; I318-L322 PolarHBondContact O-N 3.28Å; I318-V338 HydrophobicContact CG2-CG1 4.29Å; I318-V338 HydrophobicContact CG2-CG2 4.03Å; I318-L380 HydrophobicContact CD1-CD2 3.58Å; I318-I384 HydrophobicContact CG1-CD1 4.07Å; I318-I384 HydrophobicContact CG1-CG1 3.72Å
319I88.4Confident82.4Confident16 Ų1629.7 Ų29.78%0.08215%0.154CC..Hα-helixtrans-60.2-40.1179.8-72.9168.5000110.9L315 L316 Y324 M335 V338L315-I319 HydrophobicContact CB-CD1 4.49Å; L315-I319 VanDerWaalsContact O-CB 3.26Å; L315-I319 WeakPolarHBondContact O-CB 3.44Å; L315-I319 WeakPolarHBondContact O-CD1 3.35Å; L315-I319 WeakPolarHBondContact O-CG1 3.33Å; L315-I319 PolarHBondContact O-N 2.94Å; L316-I319 PolarHBondContact O-N 3.01Å; I319-Y324 HydrophobicContact CG2-CD1 3.43Å; I319-Y324 VanDerWaalsContact CG2-CD1 3.43Å; I319-Y324 HydrophobicContact CG2-CE1 4.44Å; I319-Y324 HydrophobicContact CG2-CG 3.93Å; I319-Y324 WeakPolarHBondContact O-CB 3.43Å; I319-Y324 PolarHBondContact O-N 2.88Å; I319-M335 HydrophobicContact CD1-SD 4.49Å; I319-V338 HydrophobicContact CD1-CG1 4.36Å; I319-V338 HydrophobicContact CG1-CG1 4.04Å
320V86.8Confident81Confident2 Ų239.6 Ų39.61%0.01219%0.191CC..Hα-helixtrans-65-48.5173.91630000111.5I263 L316 V317 I318 L322 G323 Y407 F410 W466I263-V320 HydrophobicContact CG2-CG2 4.05Å; L316-V320 HydrophobicContact CD2-CG2 4Å; L316-V320 WeakPolarHBondContact O-CB 3.42Å; L316-V320 VanDerWaalsContact O-CG2 3.29Å; L316-V320 WeakPolarHBondContact O-CG2 3.28Å; L316-V320 PolarHBondContact O-N 3.24Å; V317-V320 PolarHBondContact O-N 2.98Å; I318-V320 VanDerWaalsContact C-N 3.28Å; I318-V320 PolarHBondContact O-N 2.88Å; V320-L322 VanDerWaalsContact C-N 3.26Å; V320-L322 PolarHBondContact O-N 3.4Å; V320-G323 PolarHBondContact O-N 2.86Å; V320-Y407 WeakPolarHBondContact O-CE1 3.48Å; V320-Y407 PolarHBondContact O-OH 3.02Å; V320-F410 HydrophobicContact CG1-CD1 4.41Å; V320-F410 HydrophobicContact CG1-CE1 3.88Å; V320-F410 HydrophobicContact CG1-CZ 4.1Å; V320-W466 HydrophobicContact CB-CZ2 4.46Å; V320-W466 HydrophobicContact CG1-CH2 3.54Å; V320-W466 HydrophobicContact CG1-CZ2 3.16Å; V320-W466 HydrophobicContact CG1-CZ3 4.41Å
321S87.2Confident79.5Confident0 Ų038 Ų380%019%0.186CC..Hα-helixtrans-63.6-28.6178.1-69.10000113.7V317 I318 G323 S387 T391V317-S321 WeakPolarHBondContact O-CB 3.21Å; V317-S321 PolarHBondContact O-N 3.45Å; V317-S321 PolarHBondContact O-OG 3.41Å; I318-S321 PolarHBondContact O-N 3.43Å; S321-G323 PolarHBondContact O-N 2.94Å; S321-S387 CarbonylContact O-C 3.53Å; S321-T391 WeakPolarHBondContact O-CB 3.25Å; S321-T391 PolarHBondContact O-OG1 3.46Å
322L85.9Confident78.7Confident29 Ų2940.1 Ų40.115%0.15221%0.209CC..THydrogen-bonded Turntrans-77-3.1173.6-71.6167.9000114I318 V320 Y324 L331 V334 V338 S387I318-L322 HydrophobicContact CG2-CD1 3.76Å; I318-L322 HydrophobicContact CG2-CG 4.41Å; I318-L322 WeakPolarHBondContact O-CB 3.36Å; I318-L322 VanDerWaalsContact O-CG 3.3Å; I318-L322 WeakPolarHBondContact O-CG 3.28Å; I318-L322 PolarHBondContact O-N 3.28Å; V320-L322 VanDerWaalsContact C-N 3.26Å; V320-L322 PolarHBondContact O-N 3.4Å; L322-Y324 VanDerWaalsContact C-N 3.28Å; L322-Y324 PolarHBondContact O-N 2.88Å; L322-L331 HydrophobicContact CB-CD2 4.2Å; L322-L331 HydrophobicContact CD1-CD2 3.9Å; L322-V334 HydrophobicContact CD1-CG1 4.17Å; L322-V338 HydrophobicContact CD1-CG2 3.91Å; L322-S387 WeakPolarHBondContact CD2-OG 3.06Å
323G79.9Confident78.1Confident0 Ų043.1 Ų43.10%023%0.229CC..THydrogen-bonded Turntrans72.716.3178.800000114.9V320 S321 G325 I326 I327 K328V320-G323 PolarHBondContact O-N 2.86Å; S321-G323 PolarHBondContact O-N 2.94Å; G323-G325 PolarHBondContact O-N 2.72Å; G323-I326 PolarHBondContact O-N 3.37Å; G323-I327 PolarHBondContact O-N 3.42Å; G323-K328 PolarHBondContact O-N 3.35Å
324Y73.3Confident77.7Confident39 Ų3944.9 Ų44.915%0.15324%0.239CC..BIsolated β-bridgetrans-57.6139.2176.1-178.4-119.2000110.3I263 I319 L322 I326 L331 M335I263-Y324 WeakPolarHBondContact CD1-O 3.14Å; I319-Y324 HydrophobicContact CG2-CD1 3.43Å; I319-Y324 VanDerWaalsContact CG2-CD1 3.43Å; I319-Y324 HydrophobicContact CG2-CE1 4.44Å; I319-Y324 HydrophobicContact CG2-CG 3.93Å; I319-Y324 WeakPolarHBondContact O-CB 3.43Å; I319-Y324 PolarHBondContact O-N 2.88Å; L322-Y324 VanDerWaalsContact C-N 3.28Å; L322-Y324 PolarHBondContact O-N 2.88Å; Y324-I326 PolarHBondContact O-N 2.99Å; Y324-L331 HydrophobicContact CD2-CB 3.93Å; Y324-L331 HydrophobicContact CD2-CD1 4.04Å; Y324-L331 HydrophobicContact CD2-CG 4.4Å; Y324-L331 HydrophobicContact CE2-CB 4.38Å; Y324-L331 HydrophobicContact CG-CD1 4.46Å; Y324-M335 HydrophobicContact CD1-CE 4Å; Y324-M335 HydrophobicContact CD2-CE 3.93Å; Y324-M335 HydrophobicContact CE1-CE 3.74Å; Y324-M335 HydrophobicContact CE2-CE 3.7Å; Y324-M335 HydrophobicContact CG-CE 4.07Å
325G65.6Low77.3Confident27 Ų2744 Ų4428%0.27824%0.239SC..THydrogen-bonded Turntrans71.8-8176.400000116.5G323 K328G323-G325 PolarHBondContact O-N 2.72Å; G325-K328 PolarHBondContact N-O 2.96Å
326I61.5Low77Confident26 Ų2650 Ų5013%0.13327%0.265CS..THydrogen-bonded Turntrans-119.4-32.9176.6-61.6178.5000112.1G323 Y324 K403 Y407G323-I326 PolarHBondContact O-N 3.37Å; Y324-I326 PolarHBondContact O-N 2.99Å; I326-K403 HydrophobicContact CG2-CD 3.69Å; I326-K403 HydrophobicContact CG2-CG 4.11Å; I326-K403 PolarHBondContact O-NZ 2.95Å; I326-Y407 HydrophobicContact CD1-CE2 4.42Å; I326-Y407 HydrophobicContact CG2-CE2 4.48Å
327I58.1Low77Confident31 Ų3157.9 Ų57.916%0.15930%0.295CS..THydrogen-bonded Turntrans-124-39.6-174.8-52.6174.7000111G323 T391 L395G323-I327 PolarHBondContact O-N 3.42Å; I327-T391 HydrophobicContact CD1-CG2 3.53Å; I327-L395 HydrophobicContact CD1-CD1 3.91Å; I327-L395 HydrophobicContact CD1-CD2 3.73Å; I327-L395 HydrophobicContact CD1-CG 3.7Å; I327-L395 HydrophobicContact CG1-CD2 4.05Å
328K61.1Low76.9Confident125 Ų12557 Ų5754%0.54329%0.29SS..BIsolated β-bridgetrans-121.6118.9175.6-64.6-173.5179.9-177.60110.1G323 G325 R330 L331G323-K328 PolarHBondContact O-N 3.35Å; G325-K328 PolarHBondContact N-O 2.96Å; K328-R330 PolarHBondContact O-N 2.87Å; K328-L331 HydrophobicContact CB-CD1 4.3Å
329P59.1Low76.9Confident100 Ų10060.3 Ų60.365%0.64931%0.309SS*.SBendtrans-71.1-19.7-178.227.9-34.7000112.8
330R64.6Low77Confident218 Ų21861.3 Ų61.382%0.82332%0.324SS*.  trans-141.3128.3-179.4-54-178.9-169.5173.84.7108.5K328K328-R330 PolarHBondContact O-N 2.87Å
331L61.6Low77.2Confident19 Ų1963 Ų6310%0.09933%0.333CS..  trans-94.67.4-177.2-13567.9000113.7L322 Y324 K328 V334 M335L322-L331 HydrophobicContact CB-CD2 4.2Å; L322-L331 HydrophobicContact CD1-CD2 3.9Å; Y324-L331 HydrophobicContact CD2-CB 3.93Å; Y324-L331 HydrophobicContact CD2-CD1 4.04Å; Y324-L331 HydrophobicContact CD2-CG 4.4Å; Y324-L331 HydrophobicContact CE2-CB 4.38Å; Y324-L331 HydrophobicContact CG-CD1 4.46Å; K328-L331 HydrophobicContact CB-CD1 4.3Å; L331-V334 HydrophobicContact CD2-CG1 4.41Å; L331-V334 HydrophobicContact CG-CB 4.34Å; L331-V334 WeakPolarHBondContact O-CB 3.37Å; L331-V334 PolarHBondContact O-N 3.21Å; L331-V334 VanDerWaalsContact O-N 3.1Å; L331-M335 HydrophobicContact CB-CB 4.17Å; L331-M335 HydrophobicContact CB-CE 3.96Å; L331-M335 HydrophobicContact CD2-CE 4.26Å; L331-M335 PolarHBondContact O-N 2.83Å
332G77.4Confident77.5Confident51 Ų5163.2 Ų63.253%0.52634%0.335SS..Hα-helixtrans50.7-136.5174.100000114V334 M335G332-V334 PolarHBondContact O-N 3.02Å; G332-M335 PolarHBondContact O-N 3.35Å
333T81.5Confident77.8Confident102 Ų10267.2 Ų67.263%0.62636%0.355SS*.Hα-helixtrans-64.9-21.7178.153.20000113.7M335 H336 R337T333-M335 VanDerWaalsContact C-N 3.31Å; T333-M335 PolarHBondContact O-N 2.71Å; T333-H336 PolarHBondContact O-N 3.16Å; T333-R337 PolarHBondContact O-N 3.21Å
334V83.6Confident78.4Confident47 Ų4770.8 Ų70.829%0.28537%0.374SS..Hα-helixtrans-66.6-34.1177.1-174.80000110.9L322 L331 G332 H336 R337 V338 W383L322-V334 HydrophobicContact CD1-CG1 4.17Å; L331-V334 HydrophobicContact CD2-CG1 4.41Å; L331-V334 HydrophobicContact CG-CB 4.34Å; L331-V334 WeakPolarHBondContact O-CB 3.37Å; L331-V334 PolarHBondContact O-N 3.21Å; L331-V334 VanDerWaalsContact O-N 3.1Å; G332-V334 PolarHBondContact O-N 3.02Å; V334-H336 VanDerWaalsContact C-N 3.33Å; V334-H336 PolarHBondContact O-N 3.07Å; V334-R337 WeakPolarHBondContact O-CB 3.2Å; V334-R337 PolarHBondContact O-N 3.1Å; V334-V338 HydrophobicContact CG1-CG2 4.36Å; V334-V338 WeakPolarHBondContact O-CG2 3.42Å; V334-V338 PolarHBondContact O-N 3.46Å; V334-W383 HydrophobicContact CG1-CZ2 4.49Å
335M82.9Confident79.3Confident44 Ų4469 Ų6922%0.21737%0.367CS..Hα-helixtrans-58.5-45.4175.4-169.861.67900111.5I319 Y324 L331 G332 T333 R337 V338 V339I319-M335 HydrophobicContact CD1-SD 4.49Å; Y324-M335 HydrophobicContact CD1-CE 4Å; Y324-M335 HydrophobicContact CD2-CE 3.93Å; Y324-M335 HydrophobicContact CE1-CE 3.74Å; Y324-M335 HydrophobicContact CE2-CE 3.7Å; Y324-M335 HydrophobicContact CG-CE 4.07Å; L331-M335 HydrophobicContact CB-CB 4.17Å; L331-M335 HydrophobicContact CB-CE 3.96Å; L331-M335 HydrophobicContact CD2-CE 4.26Å; L331-M335 PolarHBondContact O-N 2.83Å; G332-M335 PolarHBondContact O-N 3.35Å; T333-M335 VanDerWaalsContact C-N 3.31Å; T333-M335 PolarHBondContact O-N 2.71Å; M335-R337 VanDerWaalsContact C-N 3.31Å; M335-R337 PolarHBondContact O-N 3.49Å; M335-V338 PolarHBondContact O-N 2.73Å; M335-V339 WeakPolarHBondContact O-CG2 3.49Å; M335-V339 PolarHBondContact O-N 3.41Å
336H86.5Confident80.7Confident146 Ų14670.5 Ų70.568%0.67637%0.366SS*.Hα-helixtrans-64.8-34.5178.5-67-74000112.6T333 V334 G340T333-H336 PolarHBondContact O-N 3.16Å; V334-H336 VanDerWaalsContact C-N 3.33Å; V334-H336 PolarHBondContact O-N 3.07Å; H336-G340 PolarHBondContact O-N 3.33Å
337R89.9Confident82.2Confident172 Ų17270.3 Ų70.365%0.64937%0.368SS*.Hα-helixtrans-65.2-45.1173.6-64.9178.1-177.9-177.6-0.1111.6T333 V334 M335 G340 L341T333-R337 PolarHBondContact O-N 3.21Å; V334-R337 WeakPolarHBondContact O-CB 3.2Å; V334-R337 PolarHBondContact O-N 3.1Å; M335-R337 VanDerWaalsContact C-N 3.31Å; M335-R337 PolarHBondContact O-N 3.49Å; R337-G340 PolarHBondContact O-N 2.98Å; R337-L341 WeakPolarHBondContact O-CB 3.4Å; R337-L341 PolarHBondContact O-N 3.46Å
338V89.9Confident83.7Confident1 Ų170.1 Ų70.11%0.00637%0.366CS..Hα-helixtrans-63.1-44.3177.1171.30000111.2L315 I318 I319 L322 V334 M335 L341 G342 W383L315-V338 HydrophobicContact CD2-CG1 3.69Å; L315-V338 VanDerWaalsContact CD2-O 3.28Å; L315-V338 WeakPolarHBondContact CD2-O 3.42Å; I318-V338 HydrophobicContact CG2-CG1 4.29Å; I318-V338 HydrophobicContact CG2-CG2 4.03Å; I319-V338 HydrophobicContact CD1-CG1 4.36Å; I319-V338 HydrophobicContact CG1-CG1 4.04Å; L322-V338 HydrophobicContact CD1-CG2 3.91Å; V334-V338 HydrophobicContact CG1-CG2 4.36Å; V334-V338 WeakPolarHBondContact O-CG2 3.42Å; V334-V338 PolarHBondContact O-N 3.46Å; M335-V338 PolarHBondContact O-N 2.73Å; V338-L341 PolarHBondContact O-N 2.91Å; V338-G342 PolarHBondContact O-N 3.22Å; V338-W383 HydrophobicContact CG2-CH2 3.65Å; V338-W383 HydrophobicContact CG2-CZ2 4.34Å; V338-W383 HydrophobicContact CG2-CZ3 4.25Å
339V90.1Very high85.2Confident71 Ų7164.1 Ų64.143%0.4334%0.341SS..Hα-helixtrans-63.3-44.5175.7171.70000111.8M335 L341 G342 I343M335-V339 WeakPolarHBondContact O-CG2 3.49Å; M335-V339 PolarHBondContact O-N 3.41Å; V339-L341 PolarHBondContact O-N 3.31Å; V339-G342 WeakPolarHBondContact O-CA 3.28Å; V339-G342 PolarHBondContact O-N 3.14Å; V339-G342 VanDerWaalsContact O-N 3.14Å; V339-I343 HydrophobicContact CG1-CD1 4.1Å; V339-I343 WeakPolarHBondContact O-CG1 3.39Å; V339-I343 PolarHBondContact O-N 2.92Å
340G90.9Very high86.7Confident38 Ų3859.6 Ų59.639%0.39231%0.311SS..Hα-helixtrans-60.9-42.1176.900000112.9H336 R337 G342 I343 L344H336-G340 PolarHBondContact O-N 3.33Å; R337-G340 PolarHBondContact O-N 2.98Å; G340-G342 VanDerWaalsContact C-N 3.31Å; G340-G342 PolarHBondContact O-N 3.12Å; G340-I343 PolarHBondContact O-N 2.83Å; G340-L344 PolarHBondContact O-N 3Å
341L91.3Very high87.8Confident37 Ų3750.1 Ų50.119%0.19428%0.276CS..Hα-helixtrans-66.2-33.4174.3-172.657.5000112.3R337 V338 V339 L344 Y345 L376 L380 W383R337-L341 WeakPolarHBondContact O-CB 3.4Å; R337-L341 PolarHBondContact O-N 3.46Å; V338-L341 PolarHBondContact O-N 2.91Å; V339-L341 PolarHBondContact O-N 3.31Å; L341-L344 HydrophobicContact CD1-CD2 4.37Å; L341-L344 PolarHBondContact O-N 2.93Å; L341-Y345 WeakPolarHBondContact O-CB 3.46Å; L341-Y345 PolarHBondContact O-N 3.41Å; L341-L376 HydrophobicContact CD1-CD2 3.92Å; L341-L380 HydrophobicContact CD2-CD2 3.39Å; L341-L380 HydrophobicContact CG-CD2 4.06Å; L341-W383 HydrophobicContact CD2-CE3 3.9Å; L341-W383 HydrophobicContact CD2-CZ3 3.62Å
342G91.9Very high89Confident5 Ų550.1 Ų50.15%0.05228%0.276CS..Hα-helixtrans-63.1-45.7171.900000113.6T311 V338 V339 G340 L344 Y345 F346T311-G342 VanDerWaalsContact CG2-O 3.22Å; T311-G342 WeakPolarHBondContact CG2-O 3.38Å; V338-G342 PolarHBondContact O-N 3.22Å; V339-G342 WeakPolarHBondContact O-CA 3.28Å; V339-G342 PolarHBondContact O-N 3.14Å; V339-G342 VanDerWaalsContact O-N 3.14Å; G340-G342 VanDerWaalsContact C-N 3.31Å; G340-G342 PolarHBondContact O-N 3.12Å; G342-L344 VanDerWaalsContact C-N 3.34Å; G342-Y345 PolarHBondContact O-N 3Å; G342-F346 WeakPolarHBondContact O-CB 3.43Å; G342-F346 PolarHBondContact O-N 2.82Å
343I93.3Very high89.4Confident112 Ų11247.7 Ų47.757%0.57425%0.251SS*.Hα-helixtrans-62.3-43.8176.1-66.2165.8000110.3V339 G340 F346 A347V339-I343 HydrophobicContact CG1-CD1 4.1Å; V339-I343 WeakPolarHBondContact O-CG1 3.39Å; V339-I343 PolarHBondContact O-N 2.92Å; G340-I343 PolarHBondContact O-N 2.83Å; I343-F346 PolarHBondContact O-N 3.04Å; I343-A347 PolarHBondContact O-N 3.27Å
344L92.1Very high89.5Confident75 Ų7543.4 Ų43.439%0.39323%0.225SC..Hα-helixtrans-61.1-46.8176.4-171.966.6000111.8G340 L341 G342 A347 F348 L376G340-L344 PolarHBondContact O-N 3Å; L341-L344 HydrophobicContact CD1-CD2 4.37Å; L341-L344 PolarHBondContact O-N 2.93Å; G342-L344 VanDerWaalsContact C-N 3.34Å; L344-A347 PolarHBondContact O-N 3.44Å; L344-F348 HydrophobicContact CD1-CD2 4.18Å; L344-F348 HydrophobicContact CD1-CE2 3.63Å; L344-F348 HydrophobicContact CG-CD2 4.11Å; L344-F348 HydrophobicContact CG-CE2 3.87Å; L344-F348 VanDerWaalsContact O-CD2 3.3Å; L344-F348 WeakPolarHBondContact O-CD2 3.21Å; L344-F348 PolarHBondContact O-N 3.21Å; L344-L376 HydrophobicContact CD2-CD2 4.28Å; L344-L376 HydrophobicContact CG-CD1 4.48Å
345Y93.1Very high89.5Confident3 Ų342 Ų421%0.01222%0.216CC..Hα-helixtrans-62-43.8177.1179.7-97000112.2R310 T311 R314 L341 G342 A347 F348 A349 L373 L376 D377 L380R310-Y345 HydrophobicContact CB-CE1 4.21Å; R310-Y345 PolarHBondContact NE-OH 3.21Å; T311-Y345 HydrophobicContact CG2-CD1 4.03Å; T311-Y345 WeakPolarHBondContact OG1-CD1 3.21Å; R314-Y345 VanDerWaalsContact CZ-CZ 3.43Å; R314-Y345 PolarHBondContact NH1-OH 2.99Å; R314-Y345 PolarHBondContact NH2-OH 3.49Å; L341-Y345 WeakPolarHBondContact O-CB 3.46Å; L341-Y345 PolarHBondContact O-N 3.41Å; G342-Y345 PolarHBondContact O-N 3Å; Y345-A347 VanDerWaalsContact C-N 3.32Å; Y345-A347 PolarHBondContact O-N 2.68Å; Y345-F348 PolarHBondContact O-N 3.37Å; Y345-A349 HydrophobicContact CE1-CB 3.97Å; Y345-A349 VanDerWaalsContact O-CB 3.24Å; Y345-A349 WeakPolarHBondContact O-CB 3.4Å; Y345-A349 PolarHBondContact O-N 3.42Å; Y345-L373 HydrophobicContact CD2-CD1 3.84Å; Y345-L373 HydrophobicContact CE2-CD1 3.3Å; Y345-L373 HydrophobicContact CE2-CG 4.21Å; Y345-L376 HydrophobicContact CD2-CB 4.41Å; Y345-D377 VanDerWaalsContact CE2-OD1 3.25Å; Y345-D377 WeakPolarHBondContact CE2-OD1 3.35Å; Y345-L380 HydrophobicContact CD2-CD1 4.39Å
346F94.8Very high89.2Confident57 Ų5743.8 Ų43.825%0.2522%0.22CC..Hα-helixtrans-60.7-40.3177.1178.3-115.4000112.2L304 A307 L308 T311 G342 I343 S350L304-F346 HydrophobicContact CD1-CE2 4.06Å; L304-F346 HydrophobicContact CD1-CZ 3.67Å; L304-F346 HydrophobicContact CG-CZ 4.36Å; A307-F346 HydrophobicContact CB-CD2 4.37Å; A307-F346 HydrophobicContact CB-CE2 4.26Å; L308-F346 HydrophobicContact CB-CD2 4.38Å; L308-F346 HydrophobicContact CB-CE2 3.8Å; L308-F346 HydrophobicContact CD1-CD2 4.5Å; L308-F346 HydrophobicContact CD1-CE2 4.3Å; T311-F346 HydrophobicContact CG2-CB 3.95Å; T311-F346 WeakPolarHBondContact OG1-CA 3.33Å; G342-F346 WeakPolarHBondContact O-CB 3.43Å; G342-F346 PolarHBondContact O-N 2.82Å; I343-F346 PolarHBondContact O-N 3.04Å; F346-S350 WeakPolarHBondContact CE2-OG 2.97Å; F346-S350 VanDerWaalsContact O-CB 3.28Å; F346-S350 WeakPolarHBondContact O-CB 3.38Å; F346-S350 PolarHBondContact O-N 2.77Å; F346-S350 PolarHBondContact O-OG 3.5Å
347A91.6Very high88.7Confident22 Ų2237 Ų3718%0.18219%0.189CC..Hα-helixtrans-61.3-52.6177.100000111.5F25 I343 L344 Y345 A349 S350 I351F25-A347 HydrophobicContact CE2-CB 4.33Å; I343-A347 PolarHBondContact O-N 3.27Å; L344-A347 PolarHBondContact O-N 3.44Å; Y345-A347 VanDerWaalsContact C-N 3.32Å; Y345-A347 PolarHBondContact O-N 2.68Å; A347-A349 PolarHBondContact O-N 3.18Å; A347-S350 PolarHBondContact O-N 2.65Å; A347-I351 VanDerWaalsContact O-CG1 3.32Å; A347-I351 WeakPolarHBondContact O-CG1 3.2Å; A347-I351 PolarHBondContact O-N 3.37Å
348F91.4Very high87.8Confident27 Ų2730.1 Ų30.112%0.11817%0.165CC..Hα-helixtrans-63.9-41.3177.8-74.3-69.2000112.8W21 L344 Y345 S350 I351 E352 P372 L373 L376W21-F348 AromaticContact CH2-CE1 3.71Å; W21-F348 HydrophobicContact CH2-CE1 3.71Å; W21-F348 AromaticContact CH2-CZ 3.52Å; W21-F348 HydrophobicContact CH2-CZ 3.52Å; W21-F348 AromaticContact CZ3-CE1 3.72Å; W21-F348 HydrophobicContact CZ3-CE1 3.72Å; W21-F348 HydrophobicContact CZ3-CE2 4.42Å; W21-F348 AromaticContact CZ3-CZ 3.66Å; W21-F348 HydrophobicContact CZ3-CZ 3.66Å; L344-F348 HydrophobicContact CD1-CD2 4.18Å; L344-F348 HydrophobicContact CD1-CE2 3.63Å; L344-F348 HydrophobicContact CG-CD2 4.11Å; L344-F348 HydrophobicContact CG-CE2 3.87Å; L344-F348 VanDerWaalsContact O-CD2 3.3Å; L344-F348 WeakPolarHBondContact O-CD2 3.21Å; L344-F348 PolarHBondContact O-N 3.21Å; Y345-F348 PolarHBondContact O-N 3.37Å; F348-S350 VanDerWaalsContact C-N 3.31Å; F348-S350 PolarHBondContact O-N 2.95Å; F348-I351 PolarHBondContact O-N 2.9Å; F348-E352 WeakPolarHBondContact O-CB 3.25Å; F348-E352 PolarHBondContact O-N 3.35Å; F348-P372 HydrophobicContact CD1-CB 4.12Å; F348-P372 HydrophobicContact CE1-CB 3.83Å; F348-P372 HydrophobicContact CE1-CG 4.2Å; F348-P372 HydrophobicContact CZ-CB 4.06Å; F348-L373 HydrophobicContact CB-CD1 3.79Å; F348-L376 HydrophobicContact CD2-CD1 3.52Å; F348-L376 HydrophobicContact CE2-CD1 4.06Å; F348-L376 HydrophobicContact CG-CD1 4.33Å
349A90.7Very high86.3Confident0 Ų031 Ų310%018%0.175CC..Hα-helixtrans-65.1-34178.100000112.7A307 Y345 A347 G353 L373A307-A349 HydrophobicContact CB-CB 4.04Å; Y345-A349 HydrophobicContact CE1-CB 3.97Å; Y345-A349 VanDerWaalsContact O-CB 3.24Å; Y345-A349 WeakPolarHBondContact O-CB 3.4Å; Y345-A349 PolarHBondContact O-N 3.42Å; A347-A349 PolarHBondContact O-N 3.18Å; A349-G353 PolarHBondContact O-N 3.18Å; A349-L373 HydrophobicContact CB-CD1 4.12Å
350S91.6Very high84.5Confident4 Ų430.3 Ų30.33%0.02817%0.171CC..Hα-helixtrans-73.3-40.1176-56.10000111.8L304 F346 A347 F348 G353 V354L304-S350 WeakPolarHBondContact CD1-OG 3.39Å; F346-S350 WeakPolarHBondContact CE2-OG 2.97Å; F346-S350 VanDerWaalsContact O-CB 3.28Å; F346-S350 WeakPolarHBondContact O-CB 3.38Å; F346-S350 PolarHBondContact O-N 2.77Å; F346-S350 PolarHBondContact O-OG 3.5Å; A347-S350 PolarHBondContact O-N 2.65Å; F348-S350 VanDerWaalsContact C-N 3.31Å; F348-S350 PolarHBondContact O-N 2.95Å; S350-G353 PolarHBondContact O-N 3.33Å; S350-V354 WeakPolarHBondContact O-CB 3.17Å; S350-V354 VanDerWaalsContact O-CG2 3.3Å; S350-V354 WeakPolarHBondContact O-CG2 3.34Å; S350-V354 PolarHBondContact O-N 3.4Å
351I88.3Confident82.4Confident19 Ų1935.2 Ų35.210%0.09718%0.182CC..Hα-helixtrans-63.2-46.6174.5-67.4163.8000110.2F25 L28 A347 F348 V354 L355 A369F25-I351 HydrophobicContact CD2-CD1 4.05Å; F25-I351 HydrophobicContact CD2-CG1 3.93Å; F25-I351 HydrophobicContact CE2-CD1 4.36Å; F25-I351 HydrophobicContact CE2-CG1 3.92Å; L28-I351 HydrophobicContact CD2-CG1 4.28Å; L28-I351 HydrophobicContact CD2-CG2 3.99Å; A347-I351 VanDerWaalsContact O-CG1 3.32Å; A347-I351 WeakPolarHBondContact O-CG1 3.2Å; A347-I351 PolarHBondContact O-N 3.37Å; F348-I351 PolarHBondContact O-N 2.9Å; I351-V354 PolarHBondContact O-N 3.03Å; I351-L355 HydrophobicContact CG2-CD1 3.66Å; I351-L355 HydrophobicContact CG2-CG 4.21Å; I351-L355 WeakPolarHBondContact O-CB 3.32Å; I351-L355 VanDerWaalsContact O-CG 3.28Å; I351-L355 WeakPolarHBondContact O-CG 3.5Å; I351-L355 PolarHBondContact O-N 2.92Å; I351-A369 HydrophobicContact CG2-CB 3.94Å
352E86.7Confident80.4Confident19 Ų1940.5 Ų40.59%0.08921%0.21CC..Hα-helixtrans-54.2-54.4174.3179.7-97.711900111.3R310 F348 V354 L355 R356 N370 L373R310-E352 IonicContact CZ-OE2 3.15Å; R310-E352 IonicContact NH1-OE2 2.92Å; R310-E352 PolarHBondContact NH1-OE2 3.4Å; R310-E352 IonicContact NH2-OE2 3.55Å; R310-E352 PolarHBondContact NH2-OE2 2.88Å; F348-E352 WeakPolarHBondContact O-CB 3.25Å; F348-E352 PolarHBondContact O-N 3.35Å; E352-V354 PolarHBondContact O-N 3.43Å; E352-L355 PolarHBondContact O-N 3.42Å; E352-R356 VanDerWaalsContact O-CB 3.28Å; E352-R356 WeakPolarHBondContact O-CB 3.27Å; E352-R356 PolarHBondContact O-N 3.17Å; E352-R356 IonicContact OE1-CZ 3.88Å; E352-R356 IonicContact OE1-NH1 2.82Å; E352-R356 PolarHBondContact OE1-NH1 3.43Å; E352-R356 IonicContact OE2-NH1 2.64Å; E352-N370 WeakPolarHBondContact CG-OD1 3.13Å; E352-L373 HydrophobicContact CB-CD2 3.86Å; E352-L373 HydrophobicContact CG-CD2 3.76Å
353G84.7Confident78.8Confident0 Ų041.4 Ų41.40%022%0.216CC..Hα-helixtrans-59.2-44.1-179.800000113.8A349 S350 R356 I357A349-G353 PolarHBondContact O-N 3.18Å; S350-G353 PolarHBondContact O-N 3.33Å; G353-R356 PolarHBondContact O-N 2.91Å; G353-I357 WeakPolarHBondContact O-CD1 3.18Å; G353-I357 WeakPolarHBondContact O-CG1 3.23Å; G353-I357 PolarHBondContact O-N 2.93Å
354V84.6Confident77.5Confident13 Ų1342.6 Ų42.68%0.07922%0.223CC..Hα-helixtrans-68.9-44179172.50000111.8L29 V32 I300 S350 I351 E352 R356 I357 T358L29-V354 HydrophobicContact CD2-CG2 4.04Å; V32-V354 HydrophobicContact CG2-CG1 4.03Å; I300-V354 HydrophobicContact CG2-CG2 4.44Å; S350-V354 WeakPolarHBondContact O-CB 3.17Å; S350-V354 VanDerWaalsContact O-CG2 3.3Å; S350-V354 WeakPolarHBondContact O-CG2 3.34Å; S350-V354 PolarHBondContact O-N 3.4Å; I351-V354 PolarHBondContact O-N 3.03Å; E352-V354 PolarHBondContact O-N 3.43Å; V354-R356 VanDerWaalsContact C-N 3.28Å; V354-R356 PolarHBondContact O-N 2.79Å; V354-I357 PolarHBondContact O-N 3.04Å; V354-T358 WeakPolarHBondContact O-CB 3.3Å; V354-T358 PolarHBondContact O-N 3.15Å; V354-T358 PolarHBondContact O-OG1 2.85Å
355L82.5Confident76.5Confident17 Ų1743.3 Ų43.39%0.08923%0.227CC..Hα-helixtrans-62.5-37.7176.2-71.6175000111.4I351 E352 I357 T358 G359 A369I351-L355 HydrophobicContact CG2-CD1 3.66Å; I351-L355 HydrophobicContact CG2-CG 4.21Å; I351-L355 WeakPolarHBondContact O-CB 3.32Å; I351-L355 VanDerWaalsContact O-CG 3.28Å; I351-L355 WeakPolarHBondContact O-CG 3.5Å; I351-L355 PolarHBondContact O-N 2.92Å; E352-L355 PolarHBondContact O-N 3.42Å; L355-I357 VanDerWaalsContact C-N 3.33Å; L355-I357 PolarHBondContact O-N 3.48Å; L355-T358 PolarHBondContact O-N 3.44Å; L355-G359 PolarHBondContact O-N 3.22Å; L355-G359 VanDerWaalsContact O-N 3.11Å; L355-A369 HydrophobicContact CD1-CB 3.89Å
356R77.9Confident75.4Confident81 Ų8143.7 Ų43.731%0.30623%0.23SC..Hα-helixtrans-61.2-39.1176.1-162.4176.381.3-126-1.3112.4G37 E303 E352 G353 V354G37-R356 WeakPolarHBondContact CA-O 3.42Å; E303-R356 IonicContact OE1-CZ 3.48Å; E303-R356 VanDerWaalsContact OE1-CZ 3.3Å; E303-R356 IonicContact OE1-NH1 2.58Å; E303-R356 PolarHBondContact OE1-NH1 3.49Å; E303-R356 IonicContact OE1-NH2 2.61Å; E303-R356 PolarHBondContact OE1-NH2 3.02Å; E303-R356 IonicContact OE2-CZ 3.79Å; E303-R356 IonicContact OE2-NH2 2.68Å; E303-R356 PolarHBondContact OE2-NH2 3.42Å; E352-R356 VanDerWaalsContact O-CB 3.28Å; E352-R356 WeakPolarHBondContact O-CB 3.27Å; E352-R356 PolarHBondContact O-N 3.17Å; E352-R356 IonicContact OE1-CZ 3.88Å; E352-R356 IonicContact OE1-NH1 2.82Å; E352-R356 PolarHBondContact OE1-NH1 3.43Å; E352-R356 IonicContact OE2-NH1 2.64Å; G353-R356 PolarHBondContact O-N 2.91Å; V354-R356 VanDerWaalsContact C-N 3.28Å; V354-R356 PolarHBondContact O-N 2.79Å
357I76.3Confident74.5Confident5 Ų545.7 Ų45.73%0.02624%0.243CC..Hα-helixtrans-80-36.8178-67.7161.2000112.7T35 V36 G37 L299 I300 E303 G353 V354 L355 G359T35-I357 CarbonylContact C-O 3.58Å; T35-I357 HydrophobicContact CG2-CG2 4Å; V36-I357 PolarHBondContact N-O 3Å; G37-I357 VanDerWaalsContact CA-O 3.28Å; G37-I357 WeakPolarHBondContact CA-O 3.44Å; G37-I357 PolarHBondContact N-O 3.21Å; L299-I357 HydrophobicContact CD2-CD1 4.49Å; L299-I357 HydrophobicContact CD2-CG1 4.16Å; L299-I357 HydrophobicContact CD2-CG2 3.7Å; L299-I357 HydrophobicContact CG-CD1 3.89Å; L299-I357 HydrophobicContact CG-CG1 4.08Å; L299-I357 HydrophobicContact CG-CG2 4.1Å; I300-I357 HydrophobicContact CG1-CG2 4.28Å; E303-I357 HydrophobicContact CB-CD1 3.49Å; E303-I357 VanDerWaalsContact CB-CD1 3.49Å; E303-I357 HydrophobicContact CG-CD1 3.84Å; G353-I357 WeakPolarHBondContact O-CD1 3.18Å; G353-I357 WeakPolarHBondContact O-CG1 3.23Å; G353-I357 PolarHBondContact O-N 2.93Å; V354-I357 PolarHBondContact O-N 3.04Å; L355-I357 VanDerWaalsContact C-N 3.33Å; L355-I357 PolarHBondContact O-N 3.48Å; I357-G359 PolarHBondContact O-N 3.45Å
358T69.8Low73.9Confident26 Ų2650.8 Ų50.816%0.1627%0.267CS..Hα-helixtrans-61-25173.9-53.80000110.3V32 E34 V36 V354 L355 T360V32-T358 HydrophobicContact CG1-CG2 4.1Å; V32-T358 WeakPolarHBondContact CG1-OG1 3.36Å; E34-T358 WeakPolarHBondContact O-CG2 3.22Å; V36-T358 PolarHBondContact N-O 2.83Å; V354-T358 WeakPolarHBondContact O-CB 3.3Å; V354-T358 PolarHBondContact O-N 3.15Å; V354-T358 PolarHBondContact O-OG1 2.85Å; L355-T358 PolarHBondContact O-N 3.44Å; T358-T360 VanDerWaalsContact C-N 3.34Å
359G58.3Low73.4Confident20 Ų2049.8 Ų49.821%0.20626%0.263CS..THydrogen-bonded Turntrans80.917.817400000113L355 I357 K361L355-G359 PolarHBondContact O-N 3.22Å; L355-G359 VanDerWaalsContact O-N 3.11Å; I357-G359 PolarHBondContact O-N 3.45Å; G359-K361 PolarHBondContact O-N 3.44Å
360T53.2Low73.1Confident56 Ų5653.3 Ų53.334%0.34428%0.282SS..  trans-74.636.2171-17.20000111.7T358 D362 S363 A366T358-T360 VanDerWaalsContact C-N 3.34Å; T360-D362 PolarHBondContact O-N 3.16Å; T360-S363 VanDerWaalsContact CG2-OG 3.25Å; T360-S363 WeakPolarHBondContact CG2-OG 3.27Å; T360-S363 PolarHBondContact O-N 3.05Å; T360-S363 VanDerWaalsContact O-N 3.08Å; T360-S363 PolarHBondContact O-OG 3.01Å; T360-A366 WeakPolarHBondContact O-CB 3.44Å
361K45.6Very low72.9Confident142 Ų14258.1 Ų58.162%0.61731%0.306SS*.THydrogen-bonded Turntrans-55.7-35.4-174.4-87.1-177.3170.9178.40112.7G359G359-K361 PolarHBondContact O-N 3.44Å
362D50.6Low73Confident148 Ų14859 Ų5979%0.79131%0.313SS*.THydrogen-bonded Turntrans-95.215.3-176.5-49-39.9000113.1T360T360-D362 PolarHBondContact O-N 3.16Å
363S58Low73.1Confident24 Ų2458.5 Ų58.517%0.16831%0.311CS..SBendtrans-97.6146.7173.568.20000112.4T360 L365 A366T360-S363 VanDerWaalsContact CG2-OG 3.25Å; T360-S363 WeakPolarHBondContact CG2-OG 3.27Å; T360-S363 PolarHBondContact O-N 3.05Å; T360-S363 VanDerWaalsContact O-N 3.08Å; T360-S363 PolarHBondContact O-OG 3.01Å; S363-L365 PolarHBondContact O-N 2.92Å; S363-A366 PolarHBondContact O-N 3.35Å
364D66.6Low73.3Confident137 Ų13761 Ų6173%0.73333%0.333SS*.Hα-helixtrans-51.5-27.2170.4-65-36.5000112.6L367 L368D364-L367 PolarHBondContact O-N 3Å; D364-L368 VanDerWaalsContact O-CB 3.25Å; D364-L368 WeakPolarHBondContact O-CB 3.37Å; D364-L368 PolarHBondContact O-N 2.94Å
365L70.4Confident73.6Confident90 Ų9066 Ų6647%0.47136%0.358SS..Hα-helixtrans-65.9-36.8177.3-72.690.8000113.3S363 L368 A369S363-L365 PolarHBondContact O-N 2.92Å; L365-L368 PolarHBondContact O-N 3.24Å; L365-A369 PolarHBondContact O-N 3.3Å
366A69.7Low74Confident10 Ų1066.2 Ų66.28%0.08336%0.359CS..Hα-helixtrans-68.2-40.8177.500000110.9T360 S363 A369 N370T360-A366 WeakPolarHBondContact O-CB 3.44Å; S363-A366 PolarHBondContact O-N 3.35Å; A366-A369 PolarHBondContact O-N 3.44Å; A366-N370 WeakPolarHBondContact O-CB 3.3Å; A366-N370 VanDerWaalsContact O-CG 3.31Å; A366-N370 PolarHBondContact O-N 3.38Å; A366-N370 PolarHBondContact O-ND2 3.48Å
367L75.6Confident74.6Confident100 Ų10064.7 Ų64.752%0.52436%0.357SS..Hα-helixtrans-63.7-41.8172-66.1173.3000111.6D364 A369 N370 I371D364-L367 PolarHBondContact O-N 3Å; L367-A369 PolarHBondContact O-N 2.91Å; L367-N370 PolarHBondContact O-N 2.91Å; L367-I371 WeakPolarHBondContact O-CG1 3.34Å; L367-I371 PolarHBondContact O-N 2.88Å
368L78.9Confident75.3Confident128 Ų12868.2 Ų68.267%0.6738%0.382SS*.Hα-helixtrans-62.8-27.1177.2-168.271.5000113.1D364 L365 P372D364-L368 VanDerWaalsContact O-CB 3.25Å; D364-L368 WeakPolarHBondContact O-CB 3.37Å; D364-L368 PolarHBondContact O-N 2.94Å; L365-L368 PolarHBondContact O-N 3.24Å; L368-P372 WeakPolarHBondContact O-CD 3.28Å; L368-P372 WeakPolarHBondContact O-CG 3.12Å
369A80.9Confident76.3Confident6 Ų669.7 Ų69.75%0.0539%0.393CS..Hα-helixtrans-83.4-41.3172.500000112.7I351 L355 L365 A366 L367 L373I351-A369 HydrophobicContact CG2-CB 3.94Å; L355-A369 HydrophobicContact CD1-CB 3.89Å; L365-A369 PolarHBondContact O-N 3.3Å; A366-A369 PolarHBondContact O-N 3.44Å; L367-A369 PolarHBondContact O-N 2.91Å; A369-L373 WeakPolarHBondContact O-CB 3.48Å; A369-L373 PolarHBondContact O-N 2.85Å
370N85Confident77.9Confident74 Ų7469.1 Ų69.140%0.39639%0.386SS..Hα-helixtrans-68.1-41.8-177-77.4-26.3000113.4E352 A366 L367 L373 A374E352-N370 WeakPolarHBondContact CG-OD1 3.13Å; A366-N370 WeakPolarHBondContact O-CB 3.3Å; A366-N370 VanDerWaalsContact O-CG 3.31Å; A366-N370 PolarHBondContact O-N 3.38Å; A366-N370 PolarHBondContact O-ND2 3.48Å; L367-N370 PolarHBondContact O-N 2.91Å; N370-L373 PolarHBondContact O-N 2.83Å; N370-A374 PolarHBondContact O-N 2.76Å
371I88.3Confident79.6Confident105 Ų10569 Ų6954%0.53839%0.386SS..Hα-helixtrans-63.9-50.2-175.7-66.2164.2000111.9L367 L373 A374 L375L367-I371 WeakPolarHBondContact O-CG1 3.34Å; L367-I371 PolarHBondContact O-N 2.88Å; I371-L373 VanDerWaalsContact C-N 3.29Å; I371-L373 PolarHBondContact O-N 3.19Å; I371-A374 PolarHBondContact O-N 3.46Å; I371-L375 HydrophobicContact CG2-CD1 4.28Å; I371-L375 WeakPolarHBondContact O-CG 3.44Å; I371-L375 PolarHBondContact O-N 3.32Å; I371-L375 VanDerWaalsContact O-N 3.1Å
372P89.1Confident81.8Confident37 Ų3771.3 Ų71.324%0.2439%0.391CS..Hα-helixtrans-60.9-36.3174.1-24.535.7000113.1F348 L368 L375 L376F348-P372 HydrophobicContact CD1-CB 4.12Å; F348-P372 HydrophobicContact CE1-CB 3.83Å; F348-P372 HydrophobicContact CE1-CG 4.2Å; F348-P372 HydrophobicContact CZ-CB 4.06Å; L368-P372 WeakPolarHBondContact O-CD 3.28Å; L368-P372 WeakPolarHBondContact O-CG 3.12Å; P372-L375 PolarHBondContact O-N 2.96Å; P372-L376 WeakPolarHBondContact O-CG 3.42Å; P372-L376 PolarHBondContact O-N 3.49Å
373L88.3Confident83.9Confident9 Ų967.7 Ų67.75%0.04737%0.367CS..Hα-helixtrans-63.4-47177.8-166.268.5000111Y345 F348 A349 E352 A369 N370 I371 L375 L376 D377Y345-L373 HydrophobicContact CD2-CD1 3.84Å; Y345-L373 HydrophobicContact CE2-CD1 3.3Å; Y345-L373 HydrophobicContact CE2-CG 4.21Å; F348-L373 HydrophobicContact CB-CD1 3.79Å; A349-L373 HydrophobicContact CB-CD1 4.12Å; E352-L373 HydrophobicContact CB-CD2 3.86Å; E352-L373 HydrophobicContact CG-CD2 3.76Å; A369-L373 WeakPolarHBondContact O-CB 3.48Å; A369-L373 PolarHBondContact O-N 2.85Å; N370-L373 PolarHBondContact O-N 2.83Å; I371-L373 VanDerWaalsContact C-N 3.29Å; I371-L373 PolarHBondContact O-N 3.19Å; L373-L375 VanDerWaalsContact C-N 3.33Å; L373-L375 PolarHBondContact O-N 3.42Å; L373-L376 WeakPolarHBondContact O-CB 3.44Å; L373-L376 PolarHBondContact O-N 2.81Å; L373-D377 PolarHBondContact O-N 2.66Å
374A89.6Confident85.5Confident54 Ų5467.5 Ų67.545%0.44636%0.363SS..Hα-helixtrans-63.3-35.3176.900000113.3N370 I371 S378N370-A374 PolarHBondContact O-N 2.76Å; I371-A374 PolarHBondContact O-N 3.46Å; A374-S378 WeakPolarHBondContact O-CB 3.25Å; A374-S378 PolarHBondContact O-N 2.85Å; A374-S378 PolarHBondContact O-OG 2.82Å
375L91.4Very high86.7Confident116 Ų11663.9 Ų63.961%0.60734%0.342SS*.Hα-helixtrans-67.5-42173.1-69172.3000111.7I371 P372 L373 S378 S379I371-L375 HydrophobicContact CG2-CD1 4.28Å; I371-L375 WeakPolarHBondContact O-CG 3.44Å; I371-L375 PolarHBondContact O-N 3.32Å; I371-L375 VanDerWaalsContact O-N 3.1Å; P372-L375 PolarHBondContact O-N 2.96Å; L373-L375 VanDerWaalsContact C-N 3.33Å; L373-L375 PolarHBondContact O-N 3.42Å; L375-S378 PolarHBondContact O-N 3.44Å; L375-S379 WeakPolarHBondContact O-CB 3.47Å; L375-S379 PolarHBondContact O-N 3.38Å; L375-S379 PolarHBondContact O-OG 3.2Å
376L91.3Very high87.8Confident23 Ų2361.9 Ų61.912%0.1233%0.333CS..Hα-helixtrans-60.6-49.2173.4-73.5173.1000110.7L341 L344 Y345 F348 P372 L373 S378 S379 L380L341-L376 HydrophobicContact CD1-CD2 3.92Å; L344-L376 HydrophobicContact CD2-CD2 4.28Å; L344-L376 HydrophobicContact CG-CD1 4.48Å; Y345-L376 HydrophobicContact CD2-CB 4.41Å; F348-L376 HydrophobicContact CD2-CD1 3.52Å; F348-L376 HydrophobicContact CE2-CD1 4.06Å; F348-L376 HydrophobicContact CG-CD1 4.33Å; P372-L376 WeakPolarHBondContact O-CG 3.42Å; P372-L376 PolarHBondContact O-N 3.49Å; L373-L376 WeakPolarHBondContact O-CB 3.44Å; L373-L376 PolarHBondContact O-N 2.81Å; L376-S378 VanDerWaalsContact C-N 3.3Å; L376-S378 PolarHBondContact O-N 3.18Å; L376-S379 PolarHBondContact O-N 2.88Å; L376-S379 VanDerWaalsContact O-N 3.17Å; L376-S379 PolarHBondContact O-OG 2.71Å; L376-L380 WeakPolarHBondContact O-CB 3.36Å; L376-L380 VanDerWaalsContact O-CG 3.26Å; L376-L380 WeakPolarHBondContact O-CG 3.47Å; L376-L380 PolarHBondContact O-N 3.34Å
377D89.8Confident88.7Confident48 Ų4861.5 Ų61.526%0.25733%0.329SS..Hα-helixtrans-52.7-47.1176.3-75.730000112.2R314 Y345 L373 L380 C381R314-D377 IonicContact CZ-OD1 3.85Å; R314-D377 IonicContact CZ-OD2 2.73Å; R314-D377 IonicContact NH1-OD1 2.77Å; R314-D377 PolarHBondContact NH1-OD1 3.5Å; R314-D377 IonicContact NH1-OD2 3.29Å; R314-D377 PolarHBondContact NH1-OD2 3.24Å; R314-D377 IonicContact NH2-OD1 2.7Å; R314-D377 IonicContact NH2-OD2 3.74Å; R314-D377 PolarHBondContact NH2-OD2 2.97Å; Y345-D377 VanDerWaalsContact CE2-OD1 3.25Å; Y345-D377 WeakPolarHBondContact CE2-OD1 3.35Å; L373-D377 PolarHBondContact O-N 2.66Å; D377-L380 PolarHBondContact O-N 2.97Å; D377-C381 WeakPolarHBondContact O-CB 3.29Å; D377-C381 PolarHBondContact O-N 3.19Å
378S91Very high89.4Confident79 Ų7956.8 Ų56.855%0.55231%0.305SS*.Hα-helixtrans-64.3-45.3178.3-57.90000111.9A374 L375 L376 L380 C381 W382A374-S378 WeakPolarHBondContact O-CB 3.25Å; A374-S378 PolarHBondContact O-N 2.85Å; A374-S378 PolarHBondContact O-OG 2.82Å; L375-S378 PolarHBondContact O-N 3.44Å; L376-S378 VanDerWaalsContact C-N 3.3Å; L376-S378 PolarHBondContact O-N 3.18Å; S378-L380 VanDerWaalsContact C-N 3.35Å; S378-L380 PolarHBondContact O-N 3.38Å; S378-C381 PolarHBondContact O-N 2.76Å; S378-W382 PolarHBondContact O-N 2.71Å
379S91.1Very high89.9Confident57 Ų5753.1 Ų53.140%0.39929%0.293SS..Hα-helixtrans-65.6-36.5178.275.80000112.8L375 L376 W383L375-S379 WeakPolarHBondContact O-CB 3.47Å; L375-S379 PolarHBondContact O-N 3.38Å; L375-S379 PolarHBondContact O-OG 3.2Å; L376-S379 PolarHBondContact O-N 2.88Å; L376-S379 VanDerWaalsContact O-N 3.17Å; L376-S379 PolarHBondContact O-OG 2.71Å; S379-W383 WeakPolarHBondContact O-CB 3.23Å; S379-W383 PolarHBondContact O-N 3.45Å
380L91.3Very high90.3Very high9 Ų958.4 Ų58.45%0.04732%0.317CS..Hα-helixtrans-67-46.1175.4-74.3-178.5000111I318 L341 Y345 L376 D377 S378 W382 W383 I384I318-L380 HydrophobicContact CD1-CD2 3.58Å; L341-L380 HydrophobicContact CD2-CD2 3.39Å; L341-L380 HydrophobicContact CG-CD2 4.06Å; Y345-L380 HydrophobicContact CD2-CD1 4.39Å; L376-L380 WeakPolarHBondContact O-CB 3.36Å; L376-L380 VanDerWaalsContact O-CG 3.26Å; L376-L380 WeakPolarHBondContact O-CG 3.47Å; L376-L380 PolarHBondContact O-N 3.34Å; D377-L380 PolarHBondContact O-N 2.97Å; S378-L380 VanDerWaalsContact C-N 3.35Å; S378-L380 PolarHBondContact O-N 3.38Å; L380-W382 PolarHBondContact O-N 3.24Å; L380-W383 PolarHBondContact O-N 3.44Å; L380-I384 WeakPolarHBondContact O-CB 3.29Å; L380-I384 WeakPolarHBondContact O-CD1 3.16Å; L380-I384 WeakPolarHBondContact O-CG1 3.12Å; L380-I384 PolarHBondContact O-N 2.91Å
381C90.2Very high90.4Very high53 Ų5355.5 Ų55.536%0.35830%0.302SS..Hα-helixtrans-57.7-48.2176.8-168.90000111.2D377 S378 W383 I384 F385D377-C381 WeakPolarHBondContact O-CB 3.29Å; D377-C381 PolarHBondContact O-N 3.19Å; S378-C381 PolarHBondContact O-N 2.76Å; C381-W383 PolarHBondContact O-N 3.41Å; C381-I384 PolarHBondContact O-N 3.38Å; C381-F385 VanDerWaalsContact O-CD2 3.28Å; C381-F385 WeakPolarHBondContact O-CD2 3.27Å; C381-F385 PolarHBondContact O-N 3.25Å
382W91.8Very high90.3Very high191 Ų19152 Ų5272%0.72328%0.284SS*.Hα-helixtrans-57.3-49.9173.7175.4-102.2000112.4S378 L380 I384 F385 V386S378-W382 PolarHBondContact O-N 2.71Å; L380-W382 PolarHBondContact O-N 3.24Å; W382-I384 VanDerWaalsContact C-N 3.31Å; W382-I384 PolarHBondContact O-N 3.27Å; W382-F385 PolarHBondContact O-N 3.41Å; W382-V386 HydrophobicContact CD2-CG2 4.16Å; W382-V386 HydrophobicContact CZ2-CG2 3.95Å; W382-V386 WeakPolarHBondContact O-CG2 3.08Å; W382-V386 PolarHBondContact O-N 2.94Å
383W92.9Very high90.2Very high71 Ų7157.5 Ų57.527%0.26930%0.304SS..Hα-helixtrans-64.9-34.2-178.2-170.918.6000112.6V334 V338 L341 S379 L380 C381 S387V334-W383 HydrophobicContact CG1-CZ2 4.49Å; V338-W383 HydrophobicContact CG2-CH2 3.65Å; V338-W383 HydrophobicContact CG2-CZ2 4.34Å; V338-W383 HydrophobicContact CG2-CZ3 4.25Å; L341-W383 HydrophobicContact CD2-CE3 3.9Å; L341-W383 HydrophobicContact CD2-CZ3 3.62Å; S379-W383 WeakPolarHBondContact O-CB 3.23Å; S379-W383 PolarHBondContact O-N 3.45Å; L380-W383 PolarHBondContact O-N 3.44Å; C381-W383 PolarHBondContact O-N 3.41Å; W383-S387 VanDerWaalsContact CD1-OG 3.23Å; W383-S387 PolarHBondContact NE1-OG 3.38Å; W383-S387 VanDerWaalsContact O-CB 3.26Å; W383-S387 WeakPolarHBondContact O-CB 3.46Å; W383-S387 PolarHBondContact O-N 3.34Å; W383-S387 PolarHBondContact O-OG 3.28Å
384I92.4Very high89.9Confident20 Ų2059.7 Ų59.710%0.10332%0.318CS..Hα-helixtrans-58.6-52.5172.8-73.6161000110.2V317 I318 L380 C381 W382 S387 L388 L414V317-I384 HydrophobicContact CG1-CD1 3.67Å; V317-I384 HydrophobicContact CG1-CG1 4.01Å; V317-I384 HydrophobicContact CG1-CG2 3.93Å; I318-I384 HydrophobicContact CG1-CD1 4.07Å; I318-I384 HydrophobicContact CG1-CG1 3.72Å; L380-I384 WeakPolarHBondContact O-CB 3.29Å; L380-I384 WeakPolarHBondContact O-CD1 3.16Å; L380-I384 WeakPolarHBondContact O-CG1 3.12Å; L380-I384 PolarHBondContact O-N 2.91Å; C381-I384 PolarHBondContact O-N 3.38Å; W382-I384 VanDerWaalsContact C-N 3.31Å; W382-I384 PolarHBondContact O-N 3.27Å; I384-S387 PolarHBondContact O-N 3Å; I384-L388 WeakPolarHBondContact O-CB 3.14Å; I384-L388 PolarHBondContact O-N 2.8Å; I384-L414 HydrophobicContact CG2-CD1 3.99Å
385F92.5Very high89.4Confident62 Ų6257.4 Ų57.427%0.27230%0.298SS..Hα-helixtrans-66.4-40.1-179.2-77.1-67.8000113.2C381 W382 L388 A389 L414 I415 V418C381-F385 VanDerWaalsContact O-CD2 3.28Å; C381-F385 WeakPolarHBondContact O-CD2 3.27Å; C381-F385 PolarHBondContact O-N 3.25Å; W382-F385 PolarHBondContact O-N 3.41Å; F385-L388 PolarHBondContact O-N 3.1Å; F385-A389 WeakPolarHBondContact O-CB 3.47Å; F385-A389 PolarHBondContact O-N 3.36Å; F385-L414 HydrophobicContact CE1-CB 4.08Å; F385-L414 HydrophobicContact CZ-CB 4.04Å; F385-I415 HydrophobicContact CE1-CG1 4.03Å; F385-V418 HydrophobicContact CE2-CG2 4.09Å; F385-V418 HydrophobicContact CZ-CG2 4.06Å
386V91.9Very high88.9Confident48 Ų4858.6 Ų58.629%0.29130%0.298SS..Hα-helixtrans-62.9-46.6175.7172.30000111.3W382 L388 A389 Q390W382-V386 HydrophobicContact CD2-CG2 4.16Å; W382-V386 HydrophobicContact CZ2-CG2 3.95Å; W382-V386 WeakPolarHBondContact O-CG2 3.08Å; W382-V386 PolarHBondContact O-N 2.94Å; V386-L388 VanDerWaalsContact C-N 3.32Å; V386-L388 PolarHBondContact O-N 3.38Å; V386-A389 PolarHBondContact O-N 3.05Å; V386-Q390 WeakPolarHBondContact O-CG 3.49Å; V386-Q390 PolarHBondContact O-N 3.3Å
387S89.8Confident88.5Confident1 Ų164.5 Ų64.51%0.00733%0.329CS..Hα-helixtrans-61.9-42.2177.8-57.90000111.4S321 L322 W383 I384 Q390 T391S321-S387 CarbonylContact O-C 3.53Å; L322-S387 WeakPolarHBondContact CD2-OG 3.06Å; W383-S387 VanDerWaalsContact CD1-OG 3.23Å; W383-S387 PolarHBondContact NE1-OG 3.38Å; W383-S387 VanDerWaalsContact O-CB 3.26Å; W383-S387 WeakPolarHBondContact O-CB 3.46Å; W383-S387 PolarHBondContact O-N 3.34Å; W383-S387 PolarHBondContact O-OG 3.28Å; I384-S387 PolarHBondContact O-N 3Å; S387-Q390 PolarHBondContact O-N 2.99Å; S387-T391 WeakPolarHBondContact O-CB 3.34Å; S387-T391 PolarHBondContact O-N 3.16Å; S387-T391 PolarHBondContact O-OG1 2.97Å; S387-T391 VanDerWaalsContact O-OG1 3.11Å
388L90Very high87.9Confident1 Ų167.1 Ų67.11%0.00534%0.335CS..Hα-helixtrans-65-41.9179.4-171.559.3000111.8I384 F385 V386 T391 I392 Y407 F410 T411 L414I384-L388 WeakPolarHBondContact O-CB 3.14Å; I384-L388 PolarHBondContact O-N 2.8Å; F385-L388 PolarHBondContact O-N 3.1Å; V386-L388 VanDerWaalsContact C-N 3.32Å; V386-L388 PolarHBondContact O-N 3.38Å; L388-T391 PolarHBondContact O-N 3.22Å; L388-I392 HydrophobicContact CD1-CD1 4.42Å; L388-I392 HydrophobicContact CG-CD1 4.23Å; L388-I392 WeakPolarHBondContact O-CB 3.5Å; L388-I392 VanDerWaalsContact O-CG1 3.29Å; L388-I392 WeakPolarHBondContact O-CG1 3.39Å; L388-I392 PolarHBondContact O-N 2.9Å; L388-Y407 HydrophobicContact CD1-CD1 3.59Å; L388-Y407 HydrophobicContact CD1-CE1 4.16Å; L388-F410 HydrophobicContact CD1-CD1 3.91Å; L388-F410 HydrophobicContact CD1-CE1 4.37Å; L388-F410 HydrophobicContact CD2-CD1 4.29Å; L388-T411 HydrophobicContact CD2-CG2 3.96Å; L388-T411 VanDerWaalsContact CD2-OG1 3.26Å; L388-T411 WeakPolarHBondContact CD2-OG1 3.13Å; L388-T411 WeakPolarHBondContact CG-OG1 3.26Å; L388-L414 HydrophobicContact CD2-CD1 3.96Å
389A89.8Confident87.1Confident51 Ų5172.5 Ų72.542%0.42134%0.344SS..Hα-helixtrans-64.4-42174.900000112.4F385 V386 I392 K393F385-A389 WeakPolarHBondContact O-CB 3.47Å; F385-A389 PolarHBondContact O-N 3.36Å; V386-A389 PolarHBondContact O-N 3.05Å; A389-I392 PolarHBondContact O-N 2.89Å; A389-K393 WeakPolarHBondContact O-CG 3.45Å; A389-K393 PolarHBondContact O-N 3.28Å
390Q88.9Confident86.3Confident118 Ų11872.1 Ų72.155%0.55134%0.337SS*.Hα-helixtrans-61.6-49.9173.6-71.6174.8-1.300111.1V386 S387 I392 K393 T394V386-Q390 WeakPolarHBondContact O-CG 3.49Å; V386-Q390 PolarHBondContact O-N 3.3Å; S387-Q390 PolarHBondContact O-N 2.99Å; Q390-I392 VanDerWaalsContact C-N 3.32Å; Q390-I392 PolarHBondContact O-N 3.4Å; Q390-K393 WeakPolarHBondContact O-CB 3.3Å; Q390-K393 PolarHBondContact O-N 3.35Å; Q390-K393 VanDerWaalsContact O-N 3.13Å; Q390-T394 PolarHBondContact O-N 3.4Å; Q390-T394 PolarHBondContact O-OG1 3Å
391T87Confident85.4Confident13 Ų1376.1 Ų76.18%0.0836%0.364CS..Hα-helixtrans-55.9-43.4176.8-72.80000112.4S321 I327 S387 L388 T394 L395 Y407S321-T391 WeakPolarHBondContact O-CB 3.25Å; S321-T391 PolarHBondContact O-OG1 3.46Å; I327-T391 HydrophobicContact CD1-CG2 3.53Å; S387-T391 WeakPolarHBondContact O-CB 3.34Å; S387-T391 PolarHBondContact O-N 3.16Å; S387-T391 PolarHBondContact O-OG1 2.97Å; S387-T391 VanDerWaalsContact O-OG1 3.11Å; L388-T391 PolarHBondContact O-N 3.22Å; T391-T394 PolarHBondContact O-N 2.94Å; T391-L395 HydrophobicContact CG2-CD1 4.13Å; T391-L395 WeakPolarHBondContact O-CB 3.23Å; T391-L395 WeakPolarHBondContact O-CG 3.45Å; T391-L395 PolarHBondContact O-N 3.1Å; T391-Y407 HydrophobicContact CG2-CD1 3.84Å; T391-Y407 HydrophobicContact CG2-CD2 4.47Å; T391-Y407 HydrophobicContact CG2-CE1 3.68Å; T391-Y407 HydrophobicContact CG2-CE2 4.33Å; T391-Y407 HydrophobicContact CG2-CG 4.24Å
392I86.3Confident84.8Confident32 Ų3278.3 Ų78.316%0.16438%0.375CS..Hα-helixtrans-67.3-38.9177.2-71.3166.7000111.8L388 A389 Q390 L395 K396 T411L388-I392 HydrophobicContact CD1-CD1 4.42Å; L388-I392 HydrophobicContact CG-CD1 4.23Å; L388-I392 WeakPolarHBondContact O-CB 3.5Å; L388-I392 VanDerWaalsContact O-CG1 3.29Å; L388-I392 WeakPolarHBondContact O-CG1 3.39Å; L388-I392 PolarHBondContact O-N 2.9Å; A389-I392 PolarHBondContact O-N 2.89Å; Q390-I392 VanDerWaalsContact C-N 3.32Å; Q390-I392 PolarHBondContact O-N 3.4Å; I392-L395 PolarHBondContact O-N 3.48Å; I392-K396 WeakPolarHBondContact O-CG 3.33Å; I392-K396 PolarHBondContact O-N 3.11Å; I392-T411 VanDerWaalsContact CD1-OG1 3.29Å; I392-T411 WeakPolarHBondContact CD1-OG1 3.45Å
393K86.7Confident84.2Confident151 Ų15171 Ų7166%0.65735%0.348SS*.Hα-helixtrans-60.7-47.4173.7-74.1-177.4179-169.10111.2A389 Q390 L395 K396 L397A389-K393 WeakPolarHBondContact O-CG 3.45Å; A389-K393 PolarHBondContact O-N 3.28Å; Q390-K393 WeakPolarHBondContact O-CB 3.3Å; Q390-K393 PolarHBondContact O-N 3.35Å; Q390-K393 VanDerWaalsContact O-N 3.13Å; K393-L395 PolarHBondContact O-N 2.94Å; K393-K396 WeakPolarHBondContact O-CB 3.42Å; K393-K396 PolarHBondContact O-N 3.32Å; K393-L397 WeakPolarHBondContact O-CG 3.26Å; K393-L397 PolarHBondContact O-N 3.1Å; K393-L397 VanDerWaalsContact O-N 3.16Å
394T82Confident83.5Confident55 Ų5569.7 Ų69.734%0.33735%0.346SS..Hα-helixtrans-62.4-39.8176.8-50.80000112.3Q390 T391 L397 R398Q390-T394 PolarHBondContact O-N 3.4Å; Q390-T394 PolarHBondContact O-OG1 3Å; T391-T394 PolarHBondContact O-N 2.94Å; T394-L397 PolarHBondContact O-N 3.39Å; T394-R398 WeakPolarHBondContact O-CB 3.17Å; T394-R398 WeakPolarHBondContact O-CG 3.47Å; T394-R398 PolarHBondContact O-N 3.21Å; T394-R398 VanDerWaalsContact O-N 3.09Å
395L79.1Confident83.1Confident6 Ų671.1 Ų71.13%0.03136%0.358CS..Hα-helixtrans-69.4-30.1176.5-74.8175.8000113.8I327 T391 I392 K393 K403 L404 Y407I327-L395 HydrophobicContact CD1-CD1 3.91Å; I327-L395 HydrophobicContact CD1-CD2 3.73Å; I327-L395 HydrophobicContact CD1-CG 3.7Å; I327-L395 HydrophobicContact CG1-CD2 4.05Å; T391-L395 HydrophobicContact CG2-CD1 4.13Å; T391-L395 WeakPolarHBondContact O-CB 3.23Å; T391-L395 WeakPolarHBondContact O-CG 3.45Å; T391-L395 PolarHBondContact O-N 3.1Å; I392-L395 PolarHBondContact O-N 3.48Å; K393-L395 PolarHBondContact O-N 2.94Å; L395-K403 HydrophobicContact CD1-CB 4.27Å; L395-K403 HydrophobicContact CD2-CB 3.92Å; L395-K403 HydrophobicContact CD2-CD 4.32Å; L395-L404 HydrophobicContact CB-CB 4.45Å; L395-Y407 HydrophobicContact CD1-CD2 3.43Å; L395-Y407 VanDerWaalsContact CD1-CD2 3.43Å; L395-Y407 HydrophobicContact CD1-CE2 4.04Å; L395-Y407 HydrophobicContact CD1-CG 3.94Å
396K82.2Confident82.8Confident141 Ų14170.2 Ų70.261%0.61336%0.356SS*.Hα-helixtrans-64.9-49.8172.6-83.9-178.4173.4-166.90111.3I392 K393 R398 R399 L404I392-K396 WeakPolarHBondContact O-CG 3.33Å; I392-K396 PolarHBondContact O-N 3.11Å; K393-K396 WeakPolarHBondContact O-CB 3.42Å; K393-K396 PolarHBondContact O-N 3.32Å; K396-R398 VanDerWaalsContact C-N 3.34Å; K396-R398 PolarHBondContact O-N 2.88Å; K396-R399 PolarHBondContact O-N 3.37Å; K396-L404 HydrophobicContact CB-CD1 4.25Å; K396-L404 HydrophobicContact CG-CD1 3.44Å; K396-L404 VanDerWaalsContact CG-CD1 3.44Å
397L82.3Confident82.6Confident147 Ų14768 Ų6877%0.7734%0.342SS*.Hα-helixtrans-60.6-44.2178.9-66.5170.1000111.1K393 T394 R399K393-L397 WeakPolarHBondContact O-CG 3.26Å; K393-L397 PolarHBondContact O-N 3.1Å; K393-L397 VanDerWaalsContact O-N 3.16Å; T394-L397 PolarHBondContact O-N 3.39Å; L397-R399 PolarHBondContact O-N 3.45Å
398R77.3Confident82.5Confident103 Ų10375.7 Ų75.739%0.38937%0.371SS..THydrogen-bonded Turntrans-78.621.4-179.2-64.2-177.8175.4-129.6-16.1115T394 K396 N400 D483T394-R398 WeakPolarHBondContact O-CB 3.17Å; T394-R398 WeakPolarHBondContact O-CG 3.47Å; T394-R398 PolarHBondContact O-N 3.21Å; T394-R398 VanDerWaalsContact O-N 3.09Å; K396-R398 VanDerWaalsContact C-N 3.34Å; K396-R398 PolarHBondContact O-N 2.88Å; R398-N400 PolarHBondContact O-N 3.19Å; R398-D483 IonicContact NH2-OD1 2.71Å; R398-D483 PolarHBondContact NH2-OD1 2.94Å; R398-D483 IonicContact NH2-OD2 3.72Å; R398-D483 PolarHBondContact NH2-OD2 3.36Å
399R73.1Confident82.4Confident193 Ų19380.5 Ų80.573%0.72839%0.394SS*.THydrogen-bonded Turntrans3739.9174.9-70.8-179.3170.7128.9-8.9115.7K396 L397 P401 E487K396-R399 PolarHBondContact O-N 3.37Å; L397-R399 PolarHBondContact O-N 3.45Å; R399-P401 WeakPolarHBondContact O-CD 3.46Å; R399-E487 IonicContact NH1-OE1 2.67Å; R399-E487 PolarHBondContact NH1-OE1 2.96Å
400N74.3Confident82.5Confident48 Ų4878.3 Ų78.326%0.25737%0.374SS..  trans-104.389.2-179.4-165.6-60.2000111.7R398 V402 K403 L404R398-N400 PolarHBondContact O-N 3.19Å; N400-V402 VanDerWaalsContact C-N 3.34Å; N400-V402 PolarHBondContact O-N 2.93Å; N400-K403 HydrophobicContact CB-CB 4.48Å; N400-K403 WeakPolarHBondContact OD1-CB 3.31Å; N400-K403 WeakPolarHBondContact OD1-CG 3.33Å; N400-K403 PolarHBondContact OD1-N 2.84Å; N400-K403 VanDerWaalsContact OD1-N 3.12Å; N400-L404 VanDerWaalsContact O-CB 3.26Å; N400-L404 WeakPolarHBondContact O-CB 3.38Å; N400-L404 PolarHBondContact O-N 3.46Å
401P73.8Confident82.6Confident94 Ų9473.7 Ų73.761%0.6135%0.354SS*.Hα-helixtrans-66.9-32.4-168.826-35.8000113.3R399 S405R399-P401 WeakPolarHBondContact O-CD 3.46Å; P401-S405 VanDerWaalsContact O-CB 3.32Å; P401-S405 WeakPolarHBondContact O-CB 3.31Å; P401-S405 PolarHBondContact O-N 3.39Å
402V76.4Confident82.8Confident98 Ų9877.1 Ų77.159%0.59437%0.372SS*.Hα-helixtrans-69.4-49.3-178.1-177.90000110.8N400 L404 S405 L406N400-V402 VanDerWaalsContact C-N 3.34Å; N400-V402 PolarHBondContact O-N 2.93Å; V402-L404 VanDerWaalsContact C-N 3.34Å; V402-S405 PolarHBondContact O-N 3.08Å; V402-L406 PolarHBondContact O-N 2.74Å
403K78.6Confident83.1Confident38 Ų3877 Ų7717%0.16537%0.373CS..Hα-helixtrans-64-41.2175.4-69.2178179.8-176.30110.9I326 L395 N400 S405 L406 Y407 Y475I326-K403 HydrophobicContact CG2-CD 3.69Å; I326-K403 HydrophobicContact CG2-CG 4.11Å; I326-K403 PolarHBondContact O-NZ 2.95Å; L395-K403 HydrophobicContact CD1-CB 4.27Å; L395-K403 HydrophobicContact CD2-CB 3.92Å; L395-K403 HydrophobicContact CD2-CD 4.32Å; N400-K403 HydrophobicContact CB-CB 4.48Å; N400-K403 WeakPolarHBondContact OD1-CB 3.31Å; N400-K403 WeakPolarHBondContact OD1-CG 3.33Å; N400-K403 PolarHBondContact OD1-N 2.84Å; N400-K403 VanDerWaalsContact OD1-N 3.12Å; K403-S405 PolarHBondContact O-N 3.26Å; K403-L406 PolarHBondContact O-N 3.38Å; K403-Y407 WeakPolarHBondContact O-CD2 3.3Å; K403-Y407 PolarHBondContact O-N 2.87Å; K403-Y407 VanDerWaalsContact O-N 3.11Å; K403-Y475 WeakPolarHBondContact CE-O 3.34Å; K403-Y475 PolarHBondContact NZ-O 3.09Å
404L79.9Confident83.4Confident43 Ų4370.6 Ų70.623%0.22535%0.346CS..Hα-helixtrans-61.2-42.8177.7179.6150.8000112.5L395 K396 N400 V402 Y407 R408L395-L404 HydrophobicContact CB-CB 4.45Å; K396-L404 HydrophobicContact CB-CD1 4.25Å; K396-L404 HydrophobicContact CG-CD1 3.44Å; K396-L404 VanDerWaalsContact CG-CD1 3.44Å; N400-L404 VanDerWaalsContact O-CB 3.26Å; N400-L404 WeakPolarHBondContact O-CB 3.38Å; N400-L404 PolarHBondContact O-N 3.46Å; V402-L404 VanDerWaalsContact C-N 3.34Å; L404-Y407 PolarHBondContact O-N 2.98Å; L404-R408 WeakPolarHBondContact O-CB 3.23Å; L404-R408 PolarHBondContact O-N 2.87Å
405S84.2Confident83.9Confident51 Ų5171.7 Ų71.736%0.35735%0.349SS..Hα-helixtrans-59.1-48.9176.3178.80000111.5P401 V402 K403 Y407 R408 H409P401-S405 VanDerWaalsContact O-CB 3.32Å; P401-S405 WeakPolarHBondContact O-CB 3.31Å; P401-S405 PolarHBondContact O-N 3.39Å; V402-S405 PolarHBondContact O-N 3.08Å; K403-S405 PolarHBondContact O-N 3.26Å; S405-Y407 PolarHBondContact O-N 3.2Å; S405-R408 WeakPolarHBondContact O-CB 3.4Å; S405-R408 PolarHBondContact O-N 3.11Å; S405-R408 VanDerWaalsContact O-N 3.13Å; S405-H409 PolarHBondContact O-CD2 3.33Å; S405-H409 PolarHBondContact O-N 3.08Å; S405-H409 PolarHBondContact OG-CD2 2.98Å; S405-H409 PolarHBondContact OG-NE2 3Å
406L85.4Confident84.6Confident42 Ų4277.6 Ų77.622%0.2237%0.374CS..Hα-helixtrans-55.6-49.4177.4-174163.6000111.8V402 K403 R408 H409 F410 L465 W466V402-L406 PolarHBondContact O-N 2.74Å; K403-L406 PolarHBondContact O-N 3.38Å; L406-R408 VanDerWaalsContact C-N 3.35Å; L406-R408 PolarHBondContact O-N 2.73Å; L406-H409 PolarHBondContact O-N 3.21Å; L406-F410 PolarHBondContact O-N 2.85Å; L406-L465 WeakPolarHBondContact CD1-O 3.35Å; L406-L465 HydrophobicContact CG-CB 4.44Å; L406-L465 HydrophobicContact CG-CD2 4.41Å; L406-W466 HydrophobicContact CD2-CH2 3.66Å; L406-W466 HydrophobicContact CD2-CZ2 3.34Å; L406-W466 HydrophobicContact CD2-CZ3 4.37Å
407Y87Confident85.1Confident1 Ų171 Ų710%0.00435%0.347CS..Hα-helixtrans-66.7-32.5178.1-86.9-82.1000113.3V320 I326 L388 T391 L395 K403 L404 S405 T411V320-Y407 WeakPolarHBondContact O-CE1 3.48Å; V320-Y407 PolarHBondContact O-OH 3.02Å; I326-Y407 HydrophobicContact CD1-CE2 4.42Å; I326-Y407 HydrophobicContact CG2-CE2 4.48Å; L388-Y407 HydrophobicContact CD1-CD1 3.59Å; L388-Y407 HydrophobicContact CD1-CE1 4.16Å; T391-Y407 HydrophobicContact CG2-CD1 3.84Å; T391-Y407 HydrophobicContact CG2-CD2 4.47Å; T391-Y407 HydrophobicContact CG2-CE1 3.68Å; T391-Y407 HydrophobicContact CG2-CE2 4.33Å; T391-Y407 HydrophobicContact CG2-CG 4.24Å; L395-Y407 HydrophobicContact CD1-CD2 3.43Å; L395-Y407 VanDerWaalsContact CD1-CD2 3.43Å; L395-Y407 HydrophobicContact CD1-CE2 4.04Å; L395-Y407 HydrophobicContact CD1-CG 3.94Å; K403-Y407 WeakPolarHBondContact O-CD2 3.3Å; K403-Y407 PolarHBondContact O-N 2.87Å; K403-Y407 VanDerWaalsContact O-N 3.11Å; L404-Y407 PolarHBondContact O-N 2.98Å; S405-Y407 PolarHBondContact O-N 3.2Å; Y407-T411 PolarHBondContact O-N 2.85Å; Y407-T411 PolarHBondContact O-OG1 2.95Å
408R87.5Confident85.6Confident164 Ų16466.6 Ų66.662%0.61933%0.326SS*.Hα-helixtrans-66.5-45.3173.4-172.9178.9-176.9179.1-0.4111.6L404 S405 L406 F410 T411 N412L404-R408 WeakPolarHBondContact O-CB 3.23Å; L404-R408 PolarHBondContact O-N 2.87Å; S405-R408 WeakPolarHBondContact O-CB 3.4Å; S405-R408 PolarHBondContact O-N 3.11Å; S405-R408 VanDerWaalsContact O-N 3.13Å; L406-R408 VanDerWaalsContact C-N 3.35Å; L406-R408 PolarHBondContact O-N 2.73Å; R408-F410 PolarHBondContact O-N 3.43Å; R408-T411 PolarHBondContact O-N 3.25Å; R408-N412 VanDerWaalsContact O-CG 3.24Å; R408-N412 PolarHBondContact O-N 2.82Å; R408-N412 PolarHBondContact O-OD1 2.9Å
409H89.8Confident86.3Confident102 Ų10266 Ų6647%0.47233%0.329SS..Hα-helixtrans-61.4-43.9175.4-73.6-65.1000111.8S405 L406 T411 N412 T413 L465S405-H409 PolarHBondContact O-CD2 3.33Å; S405-H409 PolarHBondContact O-N 3.08Å; S405-H409 PolarHBondContact OG-CD2 2.98Å; S405-H409 PolarHBondContact OG-NE2 3Å; L406-H409 PolarHBondContact O-N 3.21Å; H409-T411 PolarHBondContact O-N 2.68Å; H409-N412 PolarHBondContact O-N 3.28Å; H409-T413 PolarHBondContact O-N 2.89Å; H409-T413 PolarHBondContact O-OG1 3.32Å; H409-L465 HydrophobicContact CB-CD1 4.49Å; H409-L465 HydrophobicContact CB-CD2 3.96Å
410F90.7Very high87.3Confident4 Ų457.9 Ų57.92%0.01830%0.303CS..Hα-helixtrans-58.4-46.1175-175.9-124.9000112.8V317 V320 L388 L406 R408 N412 T413 L414 I462 L465 W466V317-F410 HydrophobicContact CG1-CZ 4.18Å; V320-F410 HydrophobicContact CG1-CD1 4.41Å; V320-F410 HydrophobicContact CG1-CE1 3.88Å; V320-F410 HydrophobicContact CG1-CZ 4.1Å; L388-F410 HydrophobicContact CD1-CD1 3.91Å; L388-F410 HydrophobicContact CD1-CE1 4.37Å; L388-F410 HydrophobicContact CD2-CD1 4.29Å; L406-F410 PolarHBondContact O-N 2.85Å; R408-F410 PolarHBondContact O-N 3.43Å; F410-N412 PolarHBondContact O-N 2.59Å; F410-T413 PolarHBondContact O-N 2.79Å; F410-L414 HydrophobicContact CD1-CD1 4.14Å; F410-L414 HydrophobicContact CE1-CD1 3.71Å; F410-L414 HydrophobicContact CE2-CD1 4.26Å; F410-L414 HydrophobicContact CE2-CD2 4.46Å; F410-L414 HydrophobicContact CE2-CG 4.3Å; F410-L414 HydrophobicContact CZ-CD1 3.79Å; F410-L414 HydrophobicContact CZ-CG 4.32Å; F410-L414 WeakPolarHBondContact O-CG 3.42Å; F410-L414 PolarHBondContact O-N 3.21Å; F410-I462 HydrophobicContact CD2-CG1 4.46Å; F410-I462 HydrophobicContact CE2-CD1 4.14Å; F410-I462 HydrophobicContact CE2-CG1 3.82Å; F410-L465 HydrophobicContact CB-CD1 3.92Å; F410-L465 HydrophobicContact CD2-CD1 4.32Å; F410-W466 HydrophobicContact CB-CH2 3.85Å; F410-W466 HydrophobicContact CB-CZ3 4.36Å; F410-W466 AromaticContact CD1-CH2 3.96Å; F410-W466 HydrophobicContact CD1-CH2 3.96Å; F410-W466 AromaticContact CD2-CH2 3.65Å; F410-W466 HydrophobicContact CD2-CH2 3.65Å; F410-W466 AromaticContact CD2-CZ3 3.66Å; F410-W466 HydrophobicContact CD2-CZ3 3.66Å; F410-W466 HydrophobicContact CE1-CH2 4.38Å; F410-W466 HydrophobicContact CE2-CH2 4.12Å; F410-W466 HydrophobicContact CE2-CZ3 4.06Å; F410-W466 AromaticContact CG-CH2 3.56Å; F410-W466 HydrophobicContact CG-CH2 3.56Å; F410-W466 HydrophobicContact CG-CZ3 4.04Å; F410-W466 HydrophobicContact CZ-CH2 4.44Å
411T91Very high88.1Confident22 Ų2256.4 Ų56.414%0.13530%0.297CS..Hα-helixtrans-60.4-46177-52.30000111.6L388 I392 Y407 R408 H409 T413 L414 I415L388-T411 HydrophobicContact CD2-CG2 3.96Å; L388-T411 VanDerWaalsContact CD2-OG1 3.26Å; L388-T411 WeakPolarHBondContact CD2-OG1 3.13Å; L388-T411 WeakPolarHBondContact CG-OG1 3.26Å; I392-T411 VanDerWaalsContact CD1-OG1 3.29Å; I392-T411 WeakPolarHBondContact CD1-OG1 3.45Å; Y407-T411 PolarHBondContact O-N 2.85Å; Y407-T411 PolarHBondContact O-OG1 2.95Å; R408-T411 PolarHBondContact O-N 3.25Å; H409-T411 PolarHBondContact O-N 2.68Å; T411-T413 VanDerWaalsContact C-N 3.31Å; T411-T413 PolarHBondContact O-N 3.04Å; T411-L414 PolarHBondContact O-N 2.77Å; T411-I415 HydrophobicContact CG2-CD1 3.91Å; T411-I415 HydrophobicContact CG2-CG1 4.47Å; T411-I415 WeakPolarHBondContact O-CG1 3.3Å; T411-I415 PolarHBondContact O-N 3.4Å
412N92.3Very high89Confident85 Ų8556.6 Ų56.646%0.45529%0.292SS..Hα-helixtrans-60.2-41.2178.4-702.1000111.7R408 H409 F410 I415 F416R408-N412 VanDerWaalsContact O-CG 3.24Å; R408-N412 PolarHBondContact O-N 2.82Å; R408-N412 PolarHBondContact O-OD1 2.9Å; H409-N412 PolarHBondContact O-N 3.28Å; F410-N412 PolarHBondContact O-N 2.59Å; N412-I415 PolarHBondContact O-N 2.97Å; N412-F416 WeakPolarHBondContact O-CB 3.38Å; N412-F416 PolarHBondContact O-N 2.88Å
413T92.6Very high89.8Confident28 Ų2857.2 Ų57.217%0.17229%0.291CS..Hα-helixtrans-65-42.8175.3-60.80000112.3H409 F410 T411 F416 A417 F457 V461H409-T413 PolarHBondContact O-N 2.89Å; H409-T413 PolarHBondContact O-OG1 3.32Å; F410-T413 PolarHBondContact O-N 2.79Å; T411-T413 VanDerWaalsContact C-N 3.31Å; T411-T413 PolarHBondContact O-N 3.04Å; T413-F416 PolarHBondContact O-N 2.77Å; T413-A417 WeakPolarHBondContact O-CB 3.34Å; T413-A417 PolarHBondContact O-N 2.86Å; T413-F457 HydrophobicContact CG2-CE1 4.4Å; T413-V461 HydrophobicContact CG2-CB 4.01Å; T413-V461 HydrophobicContact CG2-CG1 3.88Å; T413-V461 HydrophobicContact CG2-CG2 3.92Å
414L91.5Very high90.4Very high18 Ų1856.5 Ų56.59%0.09429%0.287CS..Hα-helixtrans-63.9-41176.7-70.6179000111.9I384 F385 L388 F410 T411 A417 V418I384-L414 HydrophobicContact CG2-CD1 3.99Å; F385-L414 HydrophobicContact CE1-CB 4.08Å; F385-L414 HydrophobicContact CZ-CB 4.04Å; L388-L414 HydrophobicContact CD2-CD1 3.96Å; F410-L414 HydrophobicContact CD1-CD1 4.14Å; F410-L414 HydrophobicContact CE1-CD1 3.71Å; F410-L414 HydrophobicContact CE2-CD1 4.26Å; F410-L414 HydrophobicContact CE2-CD2 4.46Å; F410-L414 HydrophobicContact CE2-CG 4.3Å; F410-L414 HydrophobicContact CZ-CD1 3.79Å; F410-L414 HydrophobicContact CZ-CG 4.32Å; F410-L414 WeakPolarHBondContact O-CG 3.42Å; F410-L414 PolarHBondContact O-N 3.21Å; T411-L414 PolarHBondContact O-N 2.77Å; L414-A417 PolarHBondContact O-N 2.62Å; L414-V418 WeakPolarHBondContact O-CG2 3.43Å; L414-V418 PolarHBondContact O-N 3.4Å
415I92.7Very high90.7Very high78 Ų7858.9 Ų58.940%0.430%0.299SS..Hα-helixtrans-61.1-46.9174.4-68.7168.4000110.5F385 T411 N412 A417 V418 I419F385-I415 HydrophobicContact CE1-CG1 4.03Å; T411-I415 HydrophobicContact CG2-CD1 3.91Å; T411-I415 HydrophobicContact CG2-CG1 4.47Å; T411-I415 WeakPolarHBondContact O-CG1 3.3Å; T411-I415 PolarHBondContact O-N 3.4Å; N412-I415 PolarHBondContact O-N 2.97Å; I415-A417 VanDerWaalsContact C-N 3.33Å; I415-A417 PolarHBondContact O-N 3.4Å; I415-V418 PolarHBondContact O-N 3.23Å; I415-I419 HydrophobicContact CG2-CD1 3.82Å; I415-I419 WeakPolarHBondContact O-CG1 3.43Å; I415-I419 PolarHBondContact O-N 2.99Å
416F93.8Very high90.9Very high129 Ų12959.5 Ų59.557%0.56631%0.307SS*.Hα-helixtrans-60.2-41.4176.8-178-95.3000112.2N412 T413 V418 I419 A420 F457N412-F416 WeakPolarHBondContact O-CB 3.38Å; N412-F416 PolarHBondContact O-N 2.88Å; T413-F416 PolarHBondContact O-N 2.77Å; F416-V418 PolarHBondContact O-N 2.87Å; F416-I419 PolarHBondContact O-N 3.43Å; F416-A420 WeakPolarHBondContact O-CB 3.05Å; F416-A420 PolarHBondContact O-N 2.83Å; F416-F457 HydrophobicContact CD1-CE1 4.49Å
417A92.8Very high91Very high4 Ų462.3 Ų62.33%0.03331%0.314CS..Hα-helixtrans-64.1-38.6176.800000112.9T413 L414 I415 S421 L454 I458T413-A417 WeakPolarHBondContact O-CB 3.34Å; T413-A417 PolarHBondContact O-N 2.86Å; L414-A417 PolarHBondContact O-N 2.62Å; I415-A417 VanDerWaalsContact C-N 3.33Å; I415-A417 PolarHBondContact O-N 3.4Å; A417-S421 WeakPolarHBondContact O-CB 3.41Å; A417-S421 PolarHBondContact O-N 2.79Å; A417-S421 PolarHBondContact O-OG 2.81Å; A417-L454 HydrophobicContact CB-CD1 4.04Å; A417-I458 HydrophobicContact CB-CD1 3.9Å; A417-I458 HydrophobicContact CB-CG1 4.15Å
418V92.1Very high90.9Very high54 Ų5462.5 Ų62.533%0.32732%0.316SS..Hα-helixtrans-66-45174.1171.50000111F385 L414 I415 F416 A420 S421 I422F385-V418 HydrophobicContact CE2-CG2 4.09Å; F385-V418 HydrophobicContact CZ-CG2 4.06Å; L414-V418 WeakPolarHBondContact O-CG2 3.43Å; L414-V418 PolarHBondContact O-N 3.4Å; I415-V418 PolarHBondContact O-N 3.23Å; F416-V418 PolarHBondContact O-N 2.87Å; V418-A420 PolarHBondContact O-N 2.78Å; V418-S421 WeakPolarHBondContact O-CB 3.07Å; V418-S421 PolarHBondContact O-N 2.81Å; V418-I422 HydrophobicContact CG1-CD1 3.93Å; V418-I422 WeakPolarHBondContact O-CG1 3.4Å; V418-I422 PolarHBondContact O-N 3.26Å
419I93.8Very high90.6Very high89 Ų8956.4 Ų56.446%0.45630%0.301SS..Hα-helixtrans-60.6-46.9176.6-67.6167.3000110.7I415 F416 S421 I422 I423I415-I419 HydrophobicContact CG2-CD1 3.82Å; I415-I419 WeakPolarHBondContact O-CG1 3.43Å; I415-I419 PolarHBondContact O-N 2.99Å; F416-I419 PolarHBondContact O-N 3.43Å; I419-S421 VanDerWaalsContact C-N 3.29Å; I419-S421 PolarHBondContact O-N 2.68Å; I419-I422 PolarHBondContact O-N 3.4Å; I419-I423 HydrophobicContact CG2-CD1 3.8Å; I419-I423 HydrophobicContact CG2-CG1 4.49Å; I419-I423 WeakPolarHBondContact O-CG1 3.46Å; I419-I423 PolarHBondContact O-N 2.88Å
420A93.5Very high90.2Very high23 Ų2359.3 Ų59.319%0.1931%0.312CS..Hα-helixtrans-59.6-39.617600000112.1F416 V418 F424F416-A420 WeakPolarHBondContact O-CB 3.05Å; F416-A420 PolarHBondContact O-N 2.83Å; V418-A420 PolarHBondContact O-N 2.78Å; A420-F424 WeakPolarHBondContact O-CB 3.41Å; A420-F424 PolarHBondContact O-N 3.35Å
421S91.8Very high89.4Confident18 Ų1862.5 Ų62.513%0.12633%0.326CS..Hα-helixtrans-63.6-42.8175.6-55.90000112A417 V418 I419 F424 M425 L454A417-S421 WeakPolarHBondContact O-CB 3.41Å; A417-S421 PolarHBondContact O-N 2.79Å; A417-S421 PolarHBondContact O-OG 2.81Å; V418-S421 WeakPolarHBondContact O-CB 3.07Å; V418-S421 PolarHBondContact O-N 2.81Å; I419-S421 VanDerWaalsContact C-N 3.29Å; I419-S421 PolarHBondContact O-N 2.68Å; S421-F424 PolarHBondContact O-N 3.38Å; S421-M425 WeakPolarHBondContact O-CB 3.47Å; S421-M425 VanDerWaalsContact O-CG 3.3Å; S421-M425 WeakPolarHBondContact O-CG 3.22Å; S421-M425 PolarHBondContact O-N 3.4Å; S421-L454 VanDerWaalsContact OG-CD2 3.25Å; S421-L454 WeakPolarHBondContact OG-CD2 3.07Å
422I91.4Very high88.2Confident98 Ų9862.8 Ų62.850%0.50333%0.326SS..Hα-helixtrans-66-44.4178.4-66.9165.2000111.1V418 I419 F424 M425 A426V418-I422 HydrophobicContact CG1-CD1 3.93Å; V418-I422 WeakPolarHBondContact O-CG1 3.4Å; V418-I422 PolarHBondContact O-N 3.26Å; I419-I422 PolarHBondContact O-N 3.4Å; I422-F424 VanDerWaalsContact C-N 3.32Å; I422-F424 PolarHBondContact O-N 2.91Å; I422-M425 HydrophobicContact CG1-CE 4.13Å; I422-M425 PolarHBondContact O-N 2.91Å; I422-A426 WeakPolarHBondContact O-CB 3.45Å; I422-A426 PolarHBondContact O-N 3.48Å
423I93.1Very high86.9Confident111 Ų11165.9 Ų65.957%0.56934%0.338SS*.Hα-helixtrans-60.4-44.1176-67.3167.2000110.4I419 A426 W427I419-I423 HydrophobicContact CG2-CD1 3.8Å; I419-I423 HydrophobicContact CG2-CG1 4.49Å; I419-I423 WeakPolarHBondContact O-CG1 3.46Å; I419-I423 PolarHBondContact O-N 2.88Å; I423-A426 PolarHBondContact O-N 2.61Å; I423-W427 WeakPolarHBondContact O-CB 3.32Å; I423-W427 PolarHBondContact O-N 2.78Å
424F90.9Very high85.6Confident22 Ų2270.8 Ų70.810%0.09636%0.362CS..Hα-helixtrans-65.5-44.2178.1-172-98.5000112.6A420 S421 I422 A426 W427 S428 V446 F450A420-F424 WeakPolarHBondContact O-CB 3.41Å; A420-F424 PolarHBondContact O-N 3.35Å; S421-F424 PolarHBondContact O-N 3.38Å; I422-F424 VanDerWaalsContact C-N 3.32Å; I422-F424 PolarHBondContact O-N 2.91Å; F424-A426 VanDerWaalsContact C-N 3.33Å; F424-A426 PolarHBondContact O-N 3.48Å; F424-W427 HydrophobicContact CD2-CE3 4.19Å; F424-W427 AromaticContact CE2-CE3 3.77Å; F424-W427 HydrophobicContact CE2-CE3 3.77Å; F424-W427 AromaticContact CE2-CZ3 3.8Å; F424-W427 HydrophobicContact CE2-CZ3 3.8Å; F424-W427 HydrophobicContact CZ-CE3 4.26Å; F424-W427 HydrophobicContact CZ-CZ3 4.11Å; F424-W427 PolarHBondContact O-N 3.07Å; F424-S428 WeakPolarHBondContact O-CB 3.46Å; F424-S428 PolarHBondContact O-N 2.88Å; F424-V446 HydrophobicContact CE2-CG1 4.1Å; F424-V446 HydrophobicContact CZ-CG1 4.3Å; F424-F450 HydrophobicContact CB-CD1 4.06Å; F424-F450 HydrophobicContact CB-CD2 4.28Å; F424-F450 HydrophobicContact CB-CE1 3.59Å; F424-F450 HydrophobicContact CB-CE2 3.83Å; F424-F450 HydrophobicContact CB-CG 4.38Å; F424-F450 HydrophobicContact CB-CZ 3.46Å; F424-F450 VanDerWaalsContact CB-CZ 3.46Å; F424-F450 HydrophobicContact CD1-CB 4.16Å; F424-F450 AromaticContact CD1-CD1 3.25Å; F424-F450 HydrophobicContact CD1-CD1 3.25Å; F424-F450 HydrophobicContact CD1-CD2 4.29Å; F424-F450 AromaticContact CD1-CE1 3.64Å; F424-F450 HydrophobicContact CD1-CE1 3.64Å; F424-F450 AromaticContact CD1-CG 3.63Å; F424-F450 HydrophobicContact CD1-CG 3.63Å; F424-F450 HydrophobicContact CD1-CZ 4.29Å; F424-F450 HydrophobicContact CD2-CB 4.21Å; F424-F450 HydrophobicContact CD2-CD1 4.1Å; F424-F450 AromaticContact CD2-CD2 3.58Å; F424-F450 HydrophobicContact CD2-CD2 3.58Å; F424-F450 HydrophobicContact CD2-CE1 4.41Å; F424-F450 AromaticContact CD2-CE2 3.93Å; F424-F450 HydrophobicContact CD2-CE2 3.93Å; F424-F450 AromaticContact CD2-CG 3.68Å; F424-F450 HydrophobicContact CD2-CG 3.68Å; F424-F450 HydrophobicContact CD2-CZ 4.33Å; F424-F450 HydrophobicContact CE1-CB 3.75Å; F424-F450 AromaticContact CE1-CD1 3.68Å; F424-F450 HydrophobicContact CE1-CD1 3.68Å; F424-F450 HydrophobicContact CE1-CE1 4.49Å; F424-F450 AromaticContact CE1-CG 3.76Å; F424-F450 HydrophobicContact CE1-CG 3.76Å; F424-F450 HydrophobicContact CE2-CB 3.81Å; F424-F450 HydrophobicContact CE2-CD1 4.45Å; F424-F450 AromaticContact CE2-CD2 3.98Å; F424-F450 HydrophobicContact CE2-CD2 3.98Å; F424-F450 AromaticContact CE2-CG 3.82Å; F424-F450 HydrophobicContact CE2-CG 3.82Å; F424-F450 HydrophobicContact CG-CB 4.38Å; F424-F450 AromaticContact CG-CD1 3.5Å; F424-F450 HydrophobicContact CG-CD1 3.5Å; F424-F450 AromaticContact CG-CD2 3.76Å; F424-F450 HydrophobicContact CG-CD2 3.76Å; F424-F450 AromaticContact CG-CE1 3.59Å; F424-F450 HydrophobicContact CG-CE1 3.59Å; F424-F450 AromaticContact CG-CE2 3.84Å; F424-F450 HydrophobicContact CG-CE2 3.84Å; F424-F450 AromaticContact CG-CG 3.59Å; F424-F450 HydrophobicContact CG-CG 3.59Å; F424-F450 AromaticContact CG-CZ 3.76Å; F424-F450 HydrophobicContact CG-CZ 3.76Å; F424-F450 HydrophobicContact CZ-CB 3.57Å; F424-F450 HydrophobicContact CZ-CD1 4.27Å; F424-F450 HydrophobicContact CZ-CD2 4.49Å; F424-F450 AromaticContact CZ-CG 3.86Å; F424-F450 HydrophobicContact CZ-CG 3.86Å
425M87.1Confident84.4Confident94 Ų9471.3 Ų71.346%0.46337%0.37SS..Hα-helixtrans-61-40.4175.2-74.2-175.7-63.800112S421 I422 A429 W451S421-M425 WeakPolarHBondContact O-CB 3.47Å; S421-M425 VanDerWaalsContact O-CG 3.3Å; S421-M425 WeakPolarHBondContact O-CG 3.22Å; S421-M425 PolarHBondContact O-N 3.4Å; I422-M425 HydrophobicContact CG1-CE 4.13Å; I422-M425 PolarHBondContact O-N 2.91Å; M425-A429 VanDerWaalsContact O-CB 3.26Å; M425-A429 WeakPolarHBondContact O-CB 3.28Å; M425-A429 PolarHBondContact O-N 3.04Å; M425-W451 HydrophobicContact CG-CH2 3.98Å; M425-W451 HydrophobicContact CG-CZ2 4.08Å; M425-W451 HydrophobicContact SD-CH2 4.15Å
426A87.5Confident83Confident63 Ų6375.7 Ų75.752%0.52139%0.394SS..Hα-helixtrans-66.4-39176.300000112.6I422 I423 F424 K430I422-A426 WeakPolarHBondContact O-CB 3.45Å; I422-A426 PolarHBondContact O-N 3.48Å; I423-A426 PolarHBondContact O-N 2.61Å; F424-A426 VanDerWaalsContact C-N 3.33Å; F424-A426 PolarHBondContact O-N 3.48Å; A426-K430 WeakPolarHBondContact O-CB 3.31Å; A426-K430 PolarHBondContact O-N 3.24Å; A426-K430 VanDerWaalsContact O-N 3.16Å
427W88.1Confident81.9Confident101 Ų10172.1 Ų72.138%0.38338%0.384SS..Hα-helixtrans-66.3-48.7174.1176.985000111.8I423 F424 K430 K431I423-W427 WeakPolarHBondContact O-CB 3.32Å; I423-W427 PolarHBondContact O-N 2.78Å; F424-W427 HydrophobicContact CD2-CE3 4.19Å; F424-W427 AromaticContact CE2-CE3 3.77Å; F424-W427 HydrophobicContact CE2-CE3 3.77Å; F424-W427 AromaticContact CE2-CZ3 3.8Å; F424-W427 HydrophobicContact CE2-CZ3 3.8Å; F424-W427 HydrophobicContact CZ-CE3 4.26Å; F424-W427 HydrophobicContact CZ-CZ3 4.11Å; F424-W427 PolarHBondContact O-N 3.07Å; W427-K430 PolarHBondContact O-N 3.13Å; W427-K431 HydrophobicContact CD2-CG 4.48Å; W427-K431 HydrophobicContact CZ2-CG 4.12Å; W427-K431 WeakPolarHBondContact O-CB 3.24Å; W427-K431 PolarHBondContact O-N 3.32Å
428S84.1Confident80.8Confident6 Ų672.6 Ų72.64%0.04239%0.386CS..Hα-helixtrans-57.9-50.4177.3179.20000111.1F424 K430 K431 L432 E447F424-S428 WeakPolarHBondContact O-CB 3.46Å; F424-S428 PolarHBondContact O-N 2.88Å; S428-K430 VanDerWaalsContact C-N 3.32Å; S428-K430 PolarHBondContact O-N 3.38Å; S428-K431 PolarHBondContact O-N 2.95Å; S428-K431 VanDerWaalsContact O-N 3.15Å; S428-L432 WeakPolarHBondContact O-CB 3.37Å; S428-L432 PolarHBondContact O-N 3.38Å; S428-L432 WeakPolarHBondContact OG-CD1 3.49Å; S428-E447 PolarHBondContact OG-OE1 2.92Å
429A81.9Confident79.7Confident36 Ų3673.7 Ų73.730%0.29840%0.396SS..Iπ-helixtrans-56.9-44.2176.900000112.3M425 K431 H433 L434M425-A429 VanDerWaalsContact O-CB 3.26Å; M425-A429 WeakPolarHBondContact O-CB 3.28Å; M425-A429 PolarHBondContact O-N 3.04Å; A429-K431 PolarHBondContact O-N 2.93Å; A429-H433 WeakPolarHBondContact O-CA 3.44Å; A429-H433 WeakPolarHBondContact O-CB 3.47Å; A429-H433 PolarHBondContact O-N 2.97Å; A429-L434 VanDerWaalsContact O-CD1 3.28Å; A429-L434 WeakPolarHBondContact O-CD1 3.38Å; A429-L434 PolarHBondContact O-N 2.62Å
430K81.5Confident78.7Confident162 Ų16272.6 Ų72.670%0.70439%0.391SS*.Iπ-helixtrans-65.1-38.4177.9-174.1179.9177.9-177.50113.1A426 W427 S428A426-K430 WeakPolarHBondContact O-CB 3.31Å; A426-K430 PolarHBondContact O-N 3.24Å; A426-K430 VanDerWaalsContact O-N 3.16Å; W427-K430 PolarHBondContact O-N 3.13Å; S428-K430 VanDerWaalsContact C-N 3.32Å; S428-K430 PolarHBondContact O-N 3.38Å
431K74.2Confident77.8Confident71 Ų7172.5 Ų72.531%0.30939%0.386SS..Iπ-helixtrans-84.5-39.2-175.5-86.9-73.7-153.6165.80114W427 S428 A429 D440W427-K431 HydrophobicContact CD2-CG 4.48Å; W427-K431 HydrophobicContact CZ2-CG 4.12Å; W427-K431 WeakPolarHBondContact O-CB 3.24Å; W427-K431 PolarHBondContact O-N 3.32Å; S428-K431 PolarHBondContact O-N 2.95Å; S428-K431 VanDerWaalsContact O-N 3.15Å; A429-K431 PolarHBondContact O-N 2.93Å; K431-D440 IonicContact NZ-OD2 3.06Å; K431-D440 PolarHBondContact NZ-OD2 3.08Å
432L64.9Low77.1Confident28 Ų2875.8 Ų75.815%0.14740%0.401CS..Iπ-helixtrans-101.1-41.2-172.6-57.9-178.5000112.7S428 Q438 V444S428-L432 WeakPolarHBondContact O-CB 3.37Å; S428-L432 PolarHBondContact O-N 3.38Å; S428-L432 WeakPolarHBondContact OG-CD1 3.49Å; L432-Q438 HydrophobicContact CD2-CG 4.22Å; L432-V444 HydrophobicContact CD2-CG2 4.39Å
433H66.7Low76.6Confident150 Ų15074.7 Ų74.769%0.69439%0.394SS*.Iπ-helixtrans-95.5-29.3-173.5-73.6-67.7000115.1A429A429-H433 WeakPolarHBondContact O-CA 3.44Å; A429-H433 WeakPolarHBondContact O-CB 3.47Å; A429-H433 PolarHBondContact O-N 2.97Å
434L65.2Low76Confident131 Ų13171.3 Ų71.369%0.68638%0.378SS*.SBendtrans-98.32.2-177.3-84.579.2000114.3A429A429-L434 VanDerWaalsContact O-CD1 3.28Å; A429-L434 WeakPolarHBondContact O-CD1 3.38Å; A429-L434 PolarHBondContact O-N 2.62Å
435A65.6Low75.7Confident30 Ų3073.9 Ų73.925%0.24839%0.387CS..  trans-96.8119179.700000111.4N95 C437N95-A435 PolarHBondContact ND2-O 3.1Å; A435-C437 PolarHBondContact O-N 2.92Å
436D63.7Low75.7Confident170 Ų17071.4 Ų71.491%0.90938%0.377SS*.SBendtrans-56.9-35.9177.8-63.6-51000112.5
437C70.6Confident75.6Confident54 Ų5471.8 Ų71.837%0.36537%0.368SS..SBendtrans-124.8109.1170.9175.80000109.9C93 A435 S439C93-C437 VanDerWaalsContact CA-SG 3.57Å; C93-C437 HydrophobicContact CB-CB 3.96Å; C93-C437 WeakPolarHBondContact CB-SG 3.46Å; C93-C437 WeakPolarHBondContact SG-CB 3.5Å; C93-C437 CovalentContact SG-SG 2.04Å; C93-C437 PolarHBondContact SG-SG 3.22Å; A435-C437 PolarHBondContact O-N 2.92Å; C437-S439 VanDerWaalsContact C-N 3.3Å; C437-S439 PolarHBondContact O-N 2.87Å
438Q69.6Low75.4Confident13 Ų1370.3 Ų70.36%0.06137%0.368CS..  trans-74.384.3171.3-169.7-167.8-30.800110.3Y94 N95 L432Y94-Q438 PolarHBondContact N-O 2.96Å; Y94-Q438 VanDerWaalsContact N-O 3.14Å; N95-Q438 PolarHBondContact OD1-OE1 3.44Å; L432-Q438 HydrophobicContact CD2-CG 4.22Å
439S68.2Low75.7Confident77 Ų7770.3 Ų70.354%0.53837%0.368SS..  trans-75.7-28.1176-176.90000112.7C437 W441C437-S439 VanDerWaalsContact C-N 3.3Å; C437-S439 PolarHBondContact O-N 2.87Å; S439-W441 VanDerWaalsContact O-CD1 3.25Å; S439-W441 PolarHBondContact O-N 3.07Å; S439-W441 VanDerWaalsContact O-N 3.07Å
440D73Confident76.1Confident66 Ų6670.3 Ų70.335%0.35336%0.362SS..  trans-8642.4-178.2-58.9-35000112.2K431 I442 E443K431-D440 IonicContact NZ-OD2 3.06Å; K431-D440 PolarHBondContact NZ-OD2 3.08Å; D440-I442 PolarHBondContact O-N 3.05Å; D440-I442 VanDerWaalsContact O-N 3.08Å; D440-E443 HydrophobicContact CB-CG 4.42Å; D440-E443 PolarHBondContact O-N 3Å
441W75.6Confident76.5Confident22 Ų2267.8 Ų67.88%0.08335%0.348CS..G310 helixtrans-60.4-21-177.957.6-101.3000113.7Y94 N191 I226 T227 S439 E443 V444Y94-W441 HydrophobicContact CD2-CB 3.83Å; Y94-W441 HydrophobicContact CG-CB 3.89Å; N191-W441 HydrophobicContact CB-CH2 4.47Å; I226-W441 HydrophobicContact CB-CZ3 4.49Å; I226-W441 HydrophobicContact CD1-CH2 3.93Å; I226-W441 HydrophobicContact CD1-CZ3 4.4Å; I226-W441 HydrophobicContact CG1-CH2 4.19Å; I226-W441 HydrophobicContact CG1-CZ3 4.14Å; I226-W441 HydrophobicContact CG2-CH2 3.91Å; I226-W441 HydrophobicContact CG2-CZ3 3.62Å; T227-W441 HydrophobicContact CG2-CE3 3.93Å; T227-W441 HydrophobicContact CG2-CZ3 4.35Å; S439-W441 VanDerWaalsContact O-CD1 3.25Å; S439-W441 PolarHBondContact O-N 3.07Å; S439-W441 VanDerWaalsContact O-N 3.07Å; W441-E443 PolarHBondContact O-N 2.58Å; W441-V444 VanDerWaalsContact O-CG2 3.29Å; W441-V444 WeakPolarHBondContact O-CG2 3.27Å; W441-V444 PolarHBondContact O-N 2.84Å
442I77.2Confident77.4Confident87 Ų8766.3 Ų66.345%0.44634%0.34SS..G310 helixtrans-73.3-12.8175.5-158.5165000113.1D440 W445D440-I442 PolarHBondContact O-N 3.05Å; D440-I442 VanDerWaalsContact O-N 3.08Å; I442-W445 PolarHBondContact O-NE1 2.97Å
443E80.4Confident78.7Confident75 Ų7570.5 Ų70.535%0.3536%0.357SS..G310 helixtrans-91.4-5.4175.4-62.5-172.2168.900113D440 W441 W445 V446D440-E443 HydrophobicContact CB-CG 4.42Å; D440-E443 PolarHBondContact O-N 3Å; W441-E443 PolarHBondContact O-N 2.58Å; E443-W445 VanDerWaalsContact C-N 3.29Å; E443-W445 PolarHBondContact O-N 2.8Å; E443-V446 WeakPolarHBondContact O-CB 3.1Å; E443-V446 VanDerWaalsContact O-CG2 3.27Å; E443-V446 WeakPolarHBondContact O-CG2 3.44Å; E443-V446 PolarHBondContact O-N 3.5Å
444V79.6Confident80Confident39 Ų3964.3 Ų64.324%0.23633%0.329CS..Hα-helixtrans-57.8-37.5-175.6172.20000113.2Y94 L432 W441 V446 E447Y94-V444 HydrophobicContact CE1-CG2 4.5Å; L432-V444 HydrophobicContact CD2-CG2 4.39Å; W441-V444 VanDerWaalsContact O-CG2 3.29Å; W441-V444 WeakPolarHBondContact O-CG2 3.27Å; W441-V444 PolarHBondContact O-N 2.84Å; V444-V446 PolarHBondContact O-N 3.24Å; V444-V446 VanDerWaalsContact O-N 3.11Å; V444-E447 PolarHBondContact O-N 3.23Å
445W85.3Confident81.3Confident76 Ų7660.3 Ų60.329%0.28831%0.306SS..Hα-helixtrans-62.9-18.5177.869.8-88.6000113.2P230 L231 F234 I442 E443 E447 D448 A449P230-W445 HydrophobicContact CB-CD2 3.8Å; P230-W445 HydrophobicContact CB-CE3 4.45Å; P230-W445 HydrophobicContact CB-CG 3.96Å; P230-W445 HydrophobicContact CB-CZ2 4.2Å; P230-W445 HydrophobicContact CG-CG 4.46Å; L231-W445 HydrophobicContact CB-CB 4.22Å; F234-W445 HydrophobicContact CB-CZ3 4.46Å; I442-W445 PolarHBondContact O-NE1 2.97Å; E443-W445 VanDerWaalsContact C-N 3.29Å; E443-W445 PolarHBondContact O-N 2.8Å; W445-E447 VanDerWaalsContact C-N 3.33Å; W445-D448 PolarHBondContact O-N 3.31Å; W445-A449 HydrophobicContact CE3-CB 3.72Å; W445-A449 HydrophobicContact CZ3-CB 3.74Å; W445-A449 WeakPolarHBondContact O-CB 3.4Å; W445-A449 PolarHBondContact O-N 3.15Å
446V87.8Confident82.6Confident43 Ų4359 Ų5926%0.26130%0.295SS..Hα-helixtrans-67.8-34.4179.7-178.70000111.1F424 E443 V444 D448 A449 F450F424-V446 HydrophobicContact CE2-CG1 4.1Å; F424-V446 HydrophobicContact CZ-CG1 4.3Å; E443-V446 WeakPolarHBondContact O-CB 3.1Å; E443-V446 VanDerWaalsContact O-CG2 3.27Å; E443-V446 WeakPolarHBondContact O-CG2 3.44Å; E443-V446 PolarHBondContact O-N 3.5Å; V444-V446 PolarHBondContact O-N 3.24Å; V444-V446 VanDerWaalsContact O-N 3.11Å; V446-D448 VanDerWaalsContact C-N 3.35Å; V446-A449 PolarHBondContact O-N 3.16Å; V446-F450 VanDerWaalsContact O-CB 3.23Å; V446-F450 WeakPolarHBondContact O-CB 3.45Å; V446-F450 PolarHBondContact O-N 2.86Å
447E83.6Confident84.1Confident70 Ų7054.5 Ų54.533%0.32727%0.268SS..Hα-helixtrans-58.3-49.9172.5-179.8164.7-136.800110.9S428 V444 W445 A449S428-E447 PolarHBondContact OG-OE1 2.92Å; V444-E447 PolarHBondContact O-N 3.23Å; W445-E447 VanDerWaalsContact C-N 3.33Å; E447-A449 VanDerWaalsContact C-N 3.35Å; E447-A449 PolarHBondContact O-N 3.24Å
448D84Confident85.1Confident71 Ų7153.7 Ų53.738%0.3826%0.259SS..Hα-helixtrans-68.8-32.5-179.5-126.343000112.3W445 V446 R452W445-D448 PolarHBondContact O-N 3.31Å; V446-D448 VanDerWaalsContact C-N 3.35Å; D448-R452 VanDerWaalsContact C-NH1 3.27Å; D448-R452 VanDerWaalsContact CB-NH1 3.3Å; D448-R452 WeakPolarHBondContact O-CD 3.49Å; D448-R452 WeakPolarHBondContact O-CG 3.34Å; D448-R452 PolarHBondContact O-NH1 3.27Å; D448-R452 IonicContact OD1-NH1 4Å; D448-R452 IonicContact OD2-CZ 3.02Å; D448-R452 IonicContact OD2-NH1 2.64Å; D448-R452 PolarHBondContact OD2-NH1 2.98Å; D448-R452 IonicContact OD2-NH2 2.7Å; D448-R452 PolarHBondContact OD2-NH2 3.06Å
449A90.5Very high86.2Confident6 Ų653.5 Ų53.55%0.0526%0.259CS..Hα-helixtrans-77.2-40177.600000112.9F234 W445 V446 E447 W451 R452 F453F234-A449 HydrophobicContact CD1-CB 4.04Å; F234-A449 HydrophobicContact CD2-CB 4Å; F234-A449 HydrophobicContact CE1-CB 3.9Å; F234-A449 HydrophobicContact CE2-CB 3.86Å; F234-A449 HydrophobicContact CG-CB 4.08Å; F234-A449 HydrophobicContact CZ-CB 3.79Å; F234-A449 WeakPolarHBondContact CZ-O 3.31Å; W445-A449 HydrophobicContact CE3-CB 3.72Å; W445-A449 HydrophobicContact CZ3-CB 3.74Å; W445-A449 WeakPolarHBondContact O-CB 3.4Å; W445-A449 PolarHBondContact O-N 3.15Å; V446-A449 PolarHBondContact O-N 3.16Å; E447-A449 VanDerWaalsContact C-N 3.35Å; E447-A449 PolarHBondContact O-N 3.24Å; A449-W451 PolarHBondContact O-N 3.46Å; A449-R452 PolarHBondContact O-N 2.04Å; A449-F453 WeakPolarHBondContact O-CB 3.34Å; A449-F453 PolarHBondContact O-N 3.04Å
450F91.1Very high87.5Confident36 Ų3651.9 Ų51.916%0.15824%0.244CC..Hα-helixtrans-56.6-50.8-175.4172.6-96.2000112.2F424 V446 R452 F453 L454F424-F450 HydrophobicContact CB-CD1 4.06Å; F424-F450 HydrophobicContact CB-CD2 4.28Å; F424-F450 HydrophobicContact CB-CE1 3.59Å; F424-F450 HydrophobicContact CB-CE2 3.83Å; F424-F450 HydrophobicContact CB-CG 4.38Å; F424-F450 HydrophobicContact CB-CZ 3.46Å; F424-F450 VanDerWaalsContact CB-CZ 3.46Å; F424-F450 HydrophobicContact CD1-CB 4.16Å; F424-F450 AromaticContact CD1-CD1 3.25Å; F424-F450 HydrophobicContact CD1-CD1 3.25Å; F424-F450 HydrophobicContact CD1-CD2 4.29Å; F424-F450 AromaticContact CD1-CE1 3.64Å; F424-F450 HydrophobicContact CD1-CE1 3.64Å; F424-F450 AromaticContact CD1-CG 3.63Å; F424-F450 HydrophobicContact CD1-CG 3.63Å; F424-F450 HydrophobicContact CD1-CZ 4.29Å; F424-F450 HydrophobicContact CD2-CB 4.21Å; F424-F450 HydrophobicContact CD2-CD1 4.1Å; F424-F450 AromaticContact CD2-CD2 3.58Å; F424-F450 HydrophobicContact CD2-CD2 3.58Å; F424-F450 HydrophobicContact CD2-CE1 4.41Å; F424-F450 AromaticContact CD2-CE2 3.93Å; F424-F450 HydrophobicContact CD2-CE2 3.93Å; F424-F450 AromaticContact CD2-CG 3.68Å; F424-F450 HydrophobicContact CD2-CG 3.68Å; F424-F450 HydrophobicContact CD2-CZ 4.33Å; F424-F450 HydrophobicContact CE1-CB 3.75Å; F424-F450 AromaticContact CE1-CD1 3.68Å; F424-F450 HydrophobicContact CE1-CD1 3.68Å; F424-F450 HydrophobicContact CE1-CE1 4.49Å; F424-F450 AromaticContact CE1-CG 3.76Å; F424-F450 HydrophobicContact CE1-CG 3.76Å; F424-F450 HydrophobicContact CE2-CB 3.81Å; F424-F450 HydrophobicContact CE2-CD1 4.45Å; F424-F450 AromaticContact CE2-CD2 3.98Å; F424-F450 HydrophobicContact CE2-CD2 3.98Å; F424-F450 AromaticContact CE2-CG 3.82Å; F424-F450 HydrophobicContact CE2-CG 3.82Å; F424-F450 HydrophobicContact CG-CB 4.38Å; F424-F450 AromaticContact CG-CD1 3.5Å; F424-F450 HydrophobicContact CG-CD1 3.5Å; F424-F450 AromaticContact CG-CD2 3.76Å; F424-F450 HydrophobicContact CG-CD2 3.76Å; F424-F450 AromaticContact CG-CE1 3.59Å; F424-F450 HydrophobicContact CG-CE1 3.59Å; F424-F450 AromaticContact CG-CE2 3.84Å; F424-F450 HydrophobicContact CG-CE2 3.84Å; F424-F450 AromaticContact CG-CG 3.59Å; F424-F450 HydrophobicContact CG-CG 3.59Å; F424-F450 AromaticContact CG-CZ 3.76Å; F424-F450 HydrophobicContact CG-CZ 3.76Å; F424-F450 HydrophobicContact CZ-CB 3.57Å; F424-F450 HydrophobicContact CZ-CD1 4.27Å; F424-F450 HydrophobicContact CZ-CD2 4.49Å; F424-F450 AromaticContact CZ-CG 3.86Å; F424-F450 HydrophobicContact CZ-CG 3.86Å; V446-F450 VanDerWaalsContact O-CB 3.23Å; V446-F450 WeakPolarHBondContact O-CB 3.45Å; V446-F450 PolarHBondContact O-N 2.86Å; F450-R452 VanDerWaalsContact C-N 3.28Å; F450-R452 PolarHBondContact O-N 3.42Å; F450-F453 PolarHBondContact O-N 3.16Å; F450-L454 HydrophobicContact CE1-CD2 4.13Å; F450-L454 HydrophobicContact CZ-CD2 4.28Å; F450-L454 WeakPolarHBondContact O-CB 3.21Å; F450-L454 PolarHBondContact O-N 3.24Å
451W90.6Very high88.4Confident108 Ų10850 Ų5041%0.40924%0.235SC..Hα-helixtrans-61.5-37.4-179.4-61.5115000112.5M425 A449 L454 F455M425-W451 HydrophobicContact CG-CH2 3.98Å; M425-W451 HydrophobicContact CG-CZ2 4.08Å; M425-W451 HydrophobicContact SD-CH2 4.15Å; A449-W451 PolarHBondContact O-N 3.46Å; W451-L454 HydrophobicContact CE3-CD2 4.41Å; W451-F455 WeakPolarHBondContact O-CB 3.34Å; W451-F455 PolarHBondContact O-N 2.85Å; W451-F455 VanDerWaalsContact O-N 3.1Å
452R91.4Very high89.1Confident40 Ų4049.4 Ų49.415%0.15123%0.233CC..Hα-helixtrans-72.8-36.4178.8-63.9176.8-177.2118.9-4.8111.7F234 Y235 D448 A449 F450 S456F234-R452 HydrophobicContact CE1-CB 4.02Å; F234-R452 HydrophobicContact CZ-CB 4.07Å; Y235-R452 PolarHBondContact OH-NE 3.2Å; Y235-R452 VanDerWaalsContact OH-NE 3.07Å; Y235-R452 PolarHBondContact OH-NH2 3.19Å; Y235-R452 VanDerWaalsContact OH-NH2 3.16Å; D448-R452 VanDerWaalsContact C-NH1 3.27Å; D448-R452 VanDerWaalsContact CB-NH1 3.3Å; D448-R452 WeakPolarHBondContact O-CD 3.49Å; D448-R452 WeakPolarHBondContact O-CG 3.34Å; D448-R452 PolarHBondContact O-NH1 3.27Å; D448-R452 IonicContact OD1-NH1 4Å; D448-R452 IonicContact OD2-CZ 3.02Å; D448-R452 IonicContact OD2-NH1 2.64Å; D448-R452 PolarHBondContact OD2-NH1 2.98Å; D448-R452 IonicContact OD2-NH2 2.7Å; D448-R452 PolarHBondContact OD2-NH2 3.06Å; A449-R452 PolarHBondContact O-N 2.04Å; F450-R452 VanDerWaalsContact C-N 3.28Å; F450-R452 PolarHBondContact O-N 3.42Å; R452-S456 PolarHBondContact O-N 3.37Å
453F93.6Very high89.8Confident116 Ų11645.2 Ų45.251%0.50921%0.212SC..Hα-helixtrans-67.8-48.8173.3176.7-99.9000111.7F234 A449 F450 F455 S456 F457F234-F453 HydrophobicContact CE2-CB 4.4Å; F234-F453 HydrophobicContact CZ-CB 4.38Å; A449-F453 WeakPolarHBondContact O-CB 3.34Å; A449-F453 PolarHBondContact O-N 3.04Å; F450-F453 PolarHBondContact O-N 3.16Å; F453-F455 VanDerWaalsContact C-N 3.31Å; F453-F455 PolarHBondContact O-N 3.18Å; F453-S456 WeakPolarHBondContact O-CA 3.28Å; F453-S456 WeakPolarHBondContact O-CB 2.96Å; F453-S456 PolarHBondContact O-N 2.99Å; F453-F457 PolarHBondContact O-N 3.42Å
454L92.7Very high90.2Very high20 Ų2046.7 Ų46.711%0.10522%0.217CC..Hα-helixtrans-56.9-44.1177.6-176.369.8000111.6A417 S421 F450 W451 S456 F457 I458A417-L454 HydrophobicContact CB-CD1 4.04Å; S421-L454 VanDerWaalsContact OG-CD2 3.25Å; S421-L454 WeakPolarHBondContact OG-CD2 3.07Å; F450-L454 HydrophobicContact CE1-CD2 4.13Å; F450-L454 HydrophobicContact CZ-CD2 4.28Å; F450-L454 WeakPolarHBondContact O-CB 3.21Å; F450-L454 PolarHBondContact O-N 3.24Å; W451-L454 HydrophobicContact CE3-CD2 4.41Å; L454-S456 VanDerWaalsContact C-N 3.35Å; L454-S456 PolarHBondContact O-N 3Å; L454-F457 PolarHBondContact O-N 3.49Å; L454-I458 HydrophobicContact CG-CD1 4.24Å; L454-I458 WeakPolarHBondContact O-CG1 3.38Å; L454-I458 PolarHBondContact O-N 2.92Å
455F92.6Very high90.6Very high47 Ų4746.8 Ų46.821%0.20622%0.216CC..Hα-helixtrans-57.8-45.7173.3177.8-88.4000112.2Y242 V270 K309 A313 W451 F453 F457 I458 L459Y242-F455 VanDerWaalsContact OH-CD1 3.31Å; Y242-F455 WeakPolarHBondContact OH-CD1 3.49Å; Y242-F455 WeakPolarHBondContact OH-CE1 3.5Å; V270-F455 HydrophobicContact CG1-CZ 4.22Å; K309-F455 HydrophobicContact CD-CE1 3.94Å; K309-F455 HydrophobicContact CD-CZ 4.02Å; K309-F455 HydrophobicContact CG-CZ 4.45Å; A313-F455 HydrophobicContact CB-CE2 3.43Å; A313-F455 VanDerWaalsContact CB-CE2 3.43Å; A313-F455 HydrophobicContact CB-CZ 3.55Å; W451-F455 WeakPolarHBondContact O-CB 3.34Å; W451-F455 PolarHBondContact O-N 2.85Å; W451-F455 VanDerWaalsContact O-N 3.1Å; F453-F455 VanDerWaalsContact C-N 3.31Å; F453-F455 PolarHBondContact O-N 3.18Å; F455-F457 VanDerWaalsContact C-N 3.34Å; F455-F457 PolarHBondContact O-N 3.47Å; F455-I458 PolarHBondContact O-N 2.64Å; F455-L459 WeakPolarHBondContact O-CB 3.43Å; F455-L459 PolarHBondContact O-N 2.95Å
456S93.9Very high90.6Very high2 Ų243.8 Ų43.81%0.01421%0.205CC..Hα-helixtrans-64.4-37.9178-160.30000112.5M238 Y245 R452 F453 L454 L459 L460M238-S456 VanDerWaalsContact CE-CB 3.45Å; Y245-S456 WeakPolarHBondContact CE2-OG 3.45Å; Y245-S456 PolarHBondContact OH-OG 2.98Å; R452-S456 PolarHBondContact O-N 3.37Å; F453-S456 WeakPolarHBondContact O-CA 3.28Å; F453-S456 WeakPolarHBondContact O-CB 2.96Å; F453-S456 PolarHBondContact O-N 2.99Å; L454-S456 VanDerWaalsContact C-N 3.35Å; L454-S456 PolarHBondContact O-N 3Å; S456-L459 WeakPolarHBondContact O-CB 3.15Å; S456-L459 PolarHBondContact O-N 2.98Å; S456-L460 WeakPolarHBondContact O-CB 3.29Å; S456-L460 PolarHBondContact O-N 3.39Å
457F94.5Very high90.6Very high76 Ų7648.6 Ų48.633%0.33322%0.218SC..Hα-helixtrans-65.6-44.4176.1178.1-100.4000112T413 F416 F453 L454 F455 L459 L460 V461T413-F457 HydrophobicContact CG2-CE1 4.4Å; F416-F457 HydrophobicContact CD1-CE1 4.49Å; F453-F457 PolarHBondContact O-N 3.42Å; L454-F457 PolarHBondContact O-N 3.49Å; F455-F457 VanDerWaalsContact C-N 3.34Å; F455-F457 PolarHBondContact O-N 3.47Å; F457-L459 VanDerWaalsContact C-N 3.34Å; F457-L459 PolarHBondContact O-N 3.15Å; F457-L460 WeakPolarHBondContact O-CB 3.43Å; F457-L460 PolarHBondContact O-N 3.18Å; F457-V461 HydrophobicContact CE1-CG2 4.41Å; F457-V461 HydrophobicContact CZ-CG2 4.34Å; F457-V461 PolarHBondContact O-N 3.01Å; F457-V461 VanDerWaalsContact O-N 3.11Å
458I92.6Very high90.4Very high37 Ų3745.5 Ų45.519%0.1920%0.204CC..Hα-helixtrans-62.1-43.7174.2-65164.8000110.4A417 L454 F455 L460 V461 I462A417-I458 HydrophobicContact CB-CD1 3.9Å; A417-I458 HydrophobicContact CB-CG1 4.15Å; L454-I458 HydrophobicContact CG-CD1 4.24Å; L454-I458 WeakPolarHBondContact O-CG1 3.38Å; L454-I458 PolarHBondContact O-N 2.92Å; F455-I458 PolarHBondContact O-N 2.64Å; I458-L460 VanDerWaalsContact C-N 3.33Å; I458-L460 PolarHBondContact O-N 3.36Å; I458-V461 PolarHBondContact O-N 3.24Å; I458-I462 HydrophobicContact CG2-CD1 3.92Å; I458-I462 WeakPolarHBondContact O-CG1 3.44Å; I458-I462 PolarHBondContact O-N 2.95Å
459L92.9Very high90Very high9 Ų944.3 Ų44.35%0.04720%0.202CC..Hα-helixtrans-58.1-44.5176.3-171.477.9000111.5Y242 Y245 V270 I271 F455 S456 F457 V461 I462 M463Y242-L459 HydrophobicContact CD1-CD2 4.5Å; Y242-L459 HydrophobicContact CE1-CD2 3.59Å; Y245-L459 HydrophobicContact CD2-CD2 3.99Å; Y245-L459 HydrophobicContact CE2-CD2 4.27Å; V270-L459 HydrophobicContact CB-CD1 4.48Å; V270-L459 HydrophobicContact CG1-CD1 3.7Å; I271-L459 HydrophobicContact CG1-CD1 4.48Å; I271-L459 HydrophobicContact CG1-CD2 4.08Å; I271-L459 HydrophobicContact CG1-CG 4.44Å; F455-L459 WeakPolarHBondContact O-CB 3.43Å; F455-L459 PolarHBondContact O-N 2.95Å; S456-L459 WeakPolarHBondContact O-CB 3.15Å; S456-L459 PolarHBondContact O-N 2.98Å; F457-L459 VanDerWaalsContact C-N 3.34Å; F457-L459 PolarHBondContact O-N 3.15Å; L459-V461 PolarHBondContact O-N 3.29Å; L459-I462 PolarHBondContact O-N 2.83Å; L459-M463 WeakPolarHBondContact O-CB 3.3Å; L459-M463 PolarHBondContact O-N 3.13Å
460L93.8Very high88.3Confident43 Ų4347 Ų4723%0.22522%0.224CC..Hα-helixtrans-59.7-44.2177-179.959.9000112.3Y245 S456 F457 I458 M463 F464Y245-L460 HydrophobicContact CD1-CD1 4.3Å; Y245-L460 HydrophobicContact CE1-CB 4.49Å; Y245-L460 HydrophobicContact CE1-CD1 3.71Å; Y245-L460 HydrophobicContact CE1-CG 4.46Å; Y245-L460 HydrophobicContact CE2-CB 4.36Å; S456-L460 WeakPolarHBondContact O-CB 3.29Å; S456-L460 PolarHBondContact O-N 3.39Å; F457-L460 WeakPolarHBondContact O-CB 3.43Å; F457-L460 PolarHBondContact O-N 3.18Å; I458-L460 VanDerWaalsContact C-N 3.33Å; I458-L460 PolarHBondContact O-N 3.36Å; L460-M463 HydrophobicContact CD1-CE 4.11Å; L460-M463 VanDerWaalsContact O-CB 3.27Å; L460-M463 WeakPolarHBondContact O-CB 3.14Å; L460-M463 PolarHBondContact O-N 2.73Å; L460-M463 VanDerWaalsContact O-N 3.17Å; L460-F464 HydrophobicContact CD1-CD2 3.97Å; L460-F464 HydrophobicContact CD1-CE2 3.45Å; L460-F464 VanDerWaalsContact CD1-CE2 3.45Å; L460-F464 HydrophobicContact CD1-CZ 4.24Å; L460-F464 HydrophobicContact CD2-CE2 4.41Å; L460-F464 HydrophobicContact CG-CD2 4.08Å; L460-F464 HydrophobicContact CG-CE2 3.79Å; L460-F464 VanDerWaalsContact O-CD2 3.28Å; L460-F464 WeakPolarHBondContact O-CD2 3.47Å; L460-F464 PolarHBondContact O-N 3.07Å
461V92.8Very high86.8Confident28 Ų2847.8 Ų47.817%0.1723%0.23CC..Hα-helixtrans-65.9-40.7177.21760000111.3T413 F457 I458 L459 M463 F464 L465T413-V461 HydrophobicContact CG2-CB 4.01Å; T413-V461 HydrophobicContact CG2-CG1 3.88Å; T413-V461 HydrophobicContact CG2-CG2 3.92Å; F457-V461 HydrophobicContact CE1-CG2 4.41Å; F457-V461 HydrophobicContact CZ-CG2 4.34Å; F457-V461 PolarHBondContact O-N 3.01Å; F457-V461 VanDerWaalsContact O-N 3.11Å; I458-V461 PolarHBondContact O-N 3.24Å; L459-V461 PolarHBondContact O-N 3.29Å; V461-M463 VanDerWaalsContact C-N 3.26Å; V461-M463 PolarHBondContact O-N 2.8Å; V461-F464 PolarHBondContact O-N 2.92Å; V461-L465 HydrophobicContact CG1-CD1 3.7Å; V461-L465 HydrophobicContact CG1-CG 4.17Å; V461-L465 WeakPolarHBondContact O-CB 3.37Å; V461-L465 WeakPolarHBondContact O-CG 3.35Å; V461-L465 PolarHBondContact O-N 2.88Å
462I90.1Very high85.5Confident8 Ų844.6 Ų44.64%0.04122%0.22CC..Hα-helixtrans-59.7-40.9172.1-68.2168.1000110.4I267 L316 V317 F410 I458 L459 F464 L465 W466I267-I462 HydrophobicContact CD1-CG2 4.02Å; I267-I462 HydrophobicContact CG1-CG2 4.18Å; L316-I462 HydrophobicContact CD2-CG2 4.27Å; V317-I462 HydrophobicContact CG2-CD1 4.02Å; F410-I462 HydrophobicContact CD2-CG1 4.46Å; F410-I462 HydrophobicContact CE2-CD1 4.14Å; F410-I462 HydrophobicContact CE2-CG1 3.82Å; I458-I462 HydrophobicContact CG2-CD1 3.92Å; I458-I462 WeakPolarHBondContact O-CG1 3.44Å; I458-I462 PolarHBondContact O-N 2.95Å; L459-I462 PolarHBondContact O-N 2.83Å; I462-F464 VanDerWaalsContact C-N 3.33Å; I462-F464 PolarHBondContact O-N 2.83Å; I462-L465 PolarHBondContact O-N 2.85Å; I462-W466 HydrophobicContact CB-CE3 4.24Å; I462-W466 HydrophobicContact CG1-CE3 4.45Å; I462-W466 HydrophobicContact CG1-CZ3 4.28Å; I462-W466 HydrophobicContact CG2-CE3 3.87Å; I462-W466 HydrophobicContact CG2-CZ3 4.49Å; I462-W466 PolarHBondContact O-N 2.87Å
463M91.1Very high83.7Confident0 Ų046 Ų460%023%0.229CC..Hα-helixtrans-60.9-39.9178.6-148.917677.700112.2Y245 L248 W249 W252 I271 L459 L460 V461 R467Y245-M463 HydrophobicContact CD1-CE 4.18Å; Y245-M463 HydrophobicContact CG-CE 4.35Å; Y245-M463 HydrophobicContact CG-SD 4.12Å; L248-M463 HydrophobicContact CB-CE 4.17Å; L248-M463 HydrophobicContact CD1-CE 4.32Å; W249-M463 HydrophobicContact CB-SD 4.37Å; W249-M463 HydrophobicContact CD2-CG 4.23Å; W249-M463 HydrophobicContact CE3-CG 3.33Å; W249-M463 HydrophobicContact CE3-SD 4.36Å; W249-M463 HydrophobicContact CZ3-CG 3.74Å; W249-M463 WeakPolarHBondContact CZ3-O 3.48Å; W252-M463 HydrophobicContact CH2-CE 4.34Å; W252-M463 HydrophobicContact CZ3-CE 3.98Å; W252-M463 HydrophobicContact CZ3-CG 4.19Å; I271-M463 HydrophobicContact CD1-CG 4.13Å; I271-M463 HydrophobicContact CD1-SD 3.77Å; L459-M463 WeakPolarHBondContact O-CB 3.3Å; L459-M463 PolarHBondContact O-N 3.13Å; L460-M463 HydrophobicContact CD1-CE 4.11Å; L460-M463 VanDerWaalsContact O-CB 3.27Å; L460-M463 WeakPolarHBondContact O-CB 3.14Å; L460-M463 PolarHBondContact O-N 2.73Å; L460-M463 VanDerWaalsContact O-N 3.17Å; V461-M463 VanDerWaalsContact C-N 3.26Å; V461-M463 PolarHBondContact O-N 2.8Å; M463-R467 PolarHBondContact O-N 2.85Å
464F89.7Confident81.6Confident106 Ų10650 Ų5047%0.46524%0.241SC..Hα-helixtrans-74.3-42.7175.2-76.4-63.6000113.6W252 L460 V461 I462 R467W252-F464 HydrophobicContact CH2-CD1 4.01Å; W252-F464 AromaticContact CH2-CE1 3.85Å; W252-F464 HydrophobicContact CH2-CE1 3.85Å; W252-F464 HydrophobicContact CZ2-CE1 4.44Å; L460-F464 HydrophobicContact CD1-CD2 3.97Å; L460-F464 HydrophobicContact CD1-CE2 3.45Å; L460-F464 VanDerWaalsContact CD1-CE2 3.45Å; L460-F464 HydrophobicContact CD1-CZ 4.24Å; L460-F464 HydrophobicContact CD2-CE2 4.41Å; L460-F464 HydrophobicContact CG-CD2 4.08Å; L460-F464 HydrophobicContact CG-CE2 3.79Å; L460-F464 VanDerWaalsContact O-CD2 3.28Å; L460-F464 WeakPolarHBondContact O-CD2 3.47Å; L460-F464 PolarHBondContact O-N 3.07Å; V461-F464 PolarHBondContact O-N 2.92Å; I462-F464 VanDerWaalsContact C-N 3.33Å; I462-F464 PolarHBondContact O-N 2.83Å; F464-R467 WeakPolarHBondContact O-CG 3.35Å
465L87.5Confident79.6Confident40 Ų4054.5 Ų54.521%0.20926%0.257CS..Hα-helixtrans-70.2-36.9-177-72.3174.9000112.7L406 H409 F410 V461 I462L406-L465 WeakPolarHBondContact CD1-O 3.35Å; L406-L465 HydrophobicContact CG-CB 4.44Å; L406-L465 HydrophobicContact CG-CD2 4.41Å; H409-L465 HydrophobicContact CB-CD1 4.49Å; H409-L465 HydrophobicContact CB-CD2 3.96Å; F410-L465 HydrophobicContact CB-CD1 3.92Å; F410-L465 HydrophobicContact CD2-CD1 4.32Å; V461-L465 HydrophobicContact CG1-CD1 3.7Å; V461-L465 HydrophobicContact CG1-CG 4.17Å; V461-L465 WeakPolarHBondContact O-CB 3.37Å; V461-L465 WeakPolarHBondContact O-CG 3.35Å; V461-L465 PolarHBondContact O-N 2.88Å; I462-L465 PolarHBondContact O-N 2.85Å
466W85.7Confident77.5Confident13 Ų1353.8 Ų53.85%0.04926%0.26CS..THydrogen-bonded Turntrans-10117.7-179.9-77.5-92000114.1Q264 I267 V320 L406 F410 I462Q264-W466 PolarHBondContact NE2-O 2.85Å; I267-W466 HydrophobicContact CD1-CB 3.52Å; I267-W466 HydrophobicContact CD1-CG 4.17Å; V320-W466 HydrophobicContact CB-CZ2 4.46Å; V320-W466 HydrophobicContact CG1-CH2 3.54Å; V320-W466 HydrophobicContact CG1-CZ2 3.16Å; V320-W466 HydrophobicContact CG1-CZ3 4.41Å; L406-W466 HydrophobicContact CD2-CH2 3.66Å; L406-W466 HydrophobicContact CD2-CZ2 3.34Å; L406-W466 HydrophobicContact CD2-CZ3 4.37Å; F410-W466 HydrophobicContact CB-CH2 3.85Å; F410-W466 HydrophobicContact CB-CZ3 4.36Å; F410-W466 AromaticContact CD1-CH2 3.96Å; F410-W466 HydrophobicContact CD1-CH2 3.96Å; F410-W466 AromaticContact CD2-CH2 3.65Å; F410-W466 HydrophobicContact CD2-CH2 3.65Å; F410-W466 AromaticContact CD2-CZ3 3.66Å; F410-W466 HydrophobicContact CD2-CZ3 3.66Å; F410-W466 HydrophobicContact CE1-CH2 4.38Å; F410-W466 HydrophobicContact CE2-CH2 4.12Å; F410-W466 HydrophobicContact CE2-CZ3 4.06Å; F410-W466 AromaticContact CG-CH2 3.56Å; F410-W466 HydrophobicContact CG-CH2 3.56Å; F410-W466 HydrophobicContact CG-CZ3 4.04Å; F410-W466 HydrophobicContact CZ-CH2 4.44Å; I462-W466 HydrophobicContact CB-CE3 4.24Å; I462-W466 HydrophobicContact CG1-CE3 4.45Å; I462-W466 HydrophobicContact CG1-CZ3 4.28Å; I462-W466 HydrophobicContact CG2-CE3 3.87Å; I462-W466 HydrophobicContact CG2-CZ3 4.49Å; I462-W466 PolarHBondContact O-N 2.87Å
467R87.6Confident75.2Confident144 Ų14460.5 Ų60.554%0.54329%0.289SS..  trans-52.1139.8179.172.4-174.6-174.3-164.3-0.2112W252 M463 F464W252-R467 HydrophobicContact CE3-CB 4.27Å; W252-R467 HydrophobicContact CZ3-CB 4.48Å; M463-R467 PolarHBondContact O-N 2.85Å; F464-R467 WeakPolarHBondContact O-CG 3.35Å
468P80.6Confident72.9Confident5 Ų561.2 Ų61.23%0.03230%0.3CS..  trans-53.9138.6170-26.134.5000112.4W252 Y256 L260W252-P468 HydrophobicContact CB-CB 4.47Å; W252-P468 HydrophobicContact CB-CG 4.08Å; Y256-P468 HydrophobicContact CD2-CB 3.8Å; Y256-P468 HydrophobicContact CG-CB 4.08Å; L260-P468 HydrophobicContact CD1-CB 4.01Å; L260-P468 HydrophobicContact CD1-CG 3.9Å
469S73.9Confident70.5Confident47 Ų4764.3 Ų64.333%0.32932%0.322SS..  trans-155.3139.2-177.4175.60000109.7N471 N472S469-N471 PolarHBondContact O-N 3.38Å; S469-N471 VanDerWaalsContact O-N 3.07Å; S469-N472 PolarHBondContact N-ND2 3.14Å; S469-N472 VanDerWaalsContact O-CB 3.31Å; S469-N472 WeakPolarHBondContact O-CB 3.41Å; S469-N472 VanDerWaalsContact O-CG 3.26Å; S469-N472 PolarHBondContact O-N 2.86Å; S469-N472 VanDerWaalsContact O-N 3.07Å
470A56.4Low68.5Low62 Ų6269.7 Ų69.751%0.51235%0.351SS..THydrogen-bonded Turntrans-59.5-22.3-17200000115.2Y256Y256-A470 HydrophobicContact CD1-CB 4.15Å; Y256-A470 HydrophobicContact CE1-CB 3.9Å
471N59.8Low66Low53 Ų5373.9 Ų73.928%0.28337%0.372SS..THydrogen-bonded Turntrans-942.6-179.3-138.518.4000113.6S469 Q473 R474 Y475S469-N471 PolarHBondContact O-N 3.38Å; S469-N471 VanDerWaalsContact O-N 3.07Å; N471-Q473 PolarHBondContact O-N 3.47Å; N471-R474 PolarHBondContact O-N 3.03Å; N471-R474 VanDerWaalsContact OD1-CB 3.3Å; N471-R474 WeakPolarHBondContact OD1-CB 3.33Å; N471-R474 VanDerWaalsContact OD1-CD 3.31Å; N471-R474 WeakPolarHBondContact OD1-CD 3.28Å; N471-Y475 HydrophobicContact CB-CD2 4.05Å; N471-Y475 HydrophobicContact CB-CE2 3.79Å; N471-Y475 WeakPolarHBondContact ND2-CE2 3.06Å; N471-Y475 PolarHBondContact ND2-OH 3.26Å; N471-Y475 VanDerWaalsContact ND2-OH 3.17Å; N471-Y475 VanDerWaalsContact O-CD2 3.3Å; N471-Y475 WeakPolarHBondContact O-CD2 3.39Å; N471-Y475 PolarHBondContact O-N 2.84Å
472N62Low63.4Low40 Ų4078.8 Ų78.821%0.21440%0.397CS..THydrogen-bonded Turntrans-62.9-38.1-173-78.1-4.7000113.4L261 S469 A476L261-N472 HydrophobicContact CD1-CB 4.23Å; S469-N472 PolarHBondContact N-ND2 3.14Å; S469-N472 VanDerWaalsContact O-CB 3.31Å; S469-N472 WeakPolarHBondContact O-CB 3.41Å; S469-N472 VanDerWaalsContact O-CG 3.26Å; S469-N472 PolarHBondContact O-N 2.86Å; S469-N472 VanDerWaalsContact O-N 3.07Å; N472-A476 VanDerWaalsContact O-CB 3.31Å; N472-A476 WeakPolarHBondContact O-CB 3.46Å; N472-A476 PolarHBondContact O-N 3.17Å
473Q53.3Low61.1Low70 Ų7085.3 Ų85.333%0.32743%0.432SS..THydrogen-bonded Turntrans-73.7-38.9176.5-66.6-1527.900112.6D259 N471 Y475 A476 F477D259-Q473 HydrophobicContact CB-CG 4.27Å; N471-Q473 PolarHBondContact O-N 3.47Å; Q473-Y475 VanDerWaalsContact C-N 3.27Å; Q473-Y475 PolarHBondContact O-N 2.83Å; Q473-A476 PolarHBondContact O-N 3.39Å; Q473-F477 HydrophobicContact CB-CD2 4.37Å; Q473-F477 PolarHBondContact O-N 3.45Å
474R51.1Low58.7Low200 Ų20089 Ų8976%0.75546%0.457SS*.THydrogen-bonded Turntrans-59.3-35.4176.7-91.9-179.3168.8-176.2-4.3112.9N471 T478N471-R474 PolarHBondContact O-N 3.03Å; N471-R474 VanDerWaalsContact OD1-CB 3.3Å; N471-R474 WeakPolarHBondContact OD1-CB 3.33Å; N471-R474 VanDerWaalsContact OD1-CD 3.31Å; N471-R474 WeakPolarHBondContact OD1-CD 3.28Å; R474-T478 PolarHBondContact O-N 3.35Å; R474-T478 PolarHBondContact O-OG1 2.77Å
475Y49Very low56.5Low114 Ų11493.4 Ų93.445%0.44748%0.48SS..THydrogen-bonded Turntrans-86.5-10.7173.6-65-53.9000115.1K403 N471 Q473K403-Y475 WeakPolarHBondContact CE-O 3.34Å; K403-Y475 PolarHBondContact NZ-O 3.09Å; N471-Y475 HydrophobicContact CB-CD2 4.05Å; N471-Y475 HydrophobicContact CB-CE2 3.79Å; N471-Y475 WeakPolarHBondContact ND2-CE2 3.06Å; N471-Y475 PolarHBondContact ND2-OH 3.26Å; N471-Y475 VanDerWaalsContact ND2-OH 3.17Å; N471-Y475 VanDerWaalsContact O-CD2 3.3Å; N471-Y475 WeakPolarHBondContact O-CD2 3.39Å; N471-Y475 PolarHBondContact O-N 2.84Å; Q473-Y475 VanDerWaalsContact C-N 3.27Å; Q473-Y475 PolarHBondContact O-N 2.83Å
476A49.3Very low54.6Low33 Ų3397.1 Ų97.127%0.27350%0.5SS..THydrogen-bonded Turntrans-92.4-23175.900000112.7L261 N472 Q473L261-A476 HydrophobicContact CD2-CB 4.36Å; N472-A476 VanDerWaalsContact O-CB 3.31Å; N472-A476 WeakPolarHBondContact O-CB 3.46Å; N472-A476 PolarHBondContact O-N 3.17Å; Q473-A476 PolarHBondContact O-N 3.39Å
477F45.8Very low52.9Low142 Ų142104.2 Ų104.262%0.62353%0.533SS*.SBendtrans-125.516.4-175.9-64-70.2000114.6Q473 P479Q473-F477 HydrophobicContact CB-CD2 4.37Å; Q473-F477 PolarHBondContact O-N 3.45Å; F477-P479 VanDerWaalsContact O-CD 3.26Å; F477-P479 WeakPolarHBondContact O-CD 3.49Å; F477-P479 VanDerWaalsContact O-N 3.14Å
478T44.9Very low51Low92 Ų92105 Ų10556%0.56455%0.549SS*.SBendtrans-56.1119.5155.3-39.80000106.3R474 L480R474-T478 PolarHBondContact O-N 3.35Å; R474-T478 PolarHBondContact O-OG1 2.77Å; T478-L480 PolarHBondContact O-N 2.93Å; T478-L480 VanDerWaalsContact O-N 3.14Å
479P44Very low49.4Very low102 Ų102110 Ų11066%0.66257%0.574SS**  trans-57.1126.1170.8-18.331.6000106.4F477 I481F477-P479 VanDerWaalsContact O-CD 3.26Å; F477-P479 WeakPolarHBondContact O-CD 3.49Å; F477-P479 VanDerWaalsContact O-N 3.14Å; P479-I481 PolarHBondContact O-N 3.4Å
480L49.2Very low48.2Very low122 Ų122113.8 Ų113.864%0.63959%0.586SS**  trans-68.396.2161.1-68.4151.8000103.7T478T478-L480 PolarHBondContact O-N 2.93Å; T478-L480 VanDerWaalsContact O-N 3.14Å
481I42.7Very low47.8Very low130 Ų130119.2 Ų119.267%0.66760%0.601SS**  trans-59.3149.2165.3-65176.7000106.6P479P479-I481 PolarHBondContact O-N 3.4Å
482D38.6Very low46.8Very low131 Ų131124.9 Ų124.970%0.70162%0.624SS**  trans-55.7158.4-144.5-120.5-36.1000116S484D482-S484 PolarHBondContact O-N 3.36Å
483D41.3Very low46.3Very low146 Ų146127.4 Ų127.478%0.78164%0.636SS**  trans-73.762.9154.9-70-59.5000107.4R398R398-D483 IonicContact NH2-OD1 2.71Å; R398-D483 PolarHBondContact NH2-OD1 2.94Å; R398-D483 IonicContact NH2-OD2 3.72Å; R398-D483 PolarHBondContact NH2-OD2 3.36Å
484S39.7Very low46Very low76 Ų76127.1 Ų127.153%0.53165%0.646SS.*  trans-111.2126.2174.558.10000110.4D482 D486D482-S484 PolarHBondContact O-N 3.36Å; S484-D486 PolarHBondContact O-N 2.69Å
485E44.1Very low45.8Very low199 Ų199121.1 Ų121.193%0.9364%0.635SS**SBendtrans-7082-175.5-60.2167.2147.600111.9
486D46.9Very low45.6Very low119 Ų119118.8 Ų118.864%0.63664%0.635SS**  trans-156.760.5171.8-88.2-44.5000110.6S484 D488S484-D486 PolarHBondContact O-N 2.69Å; D486-D488 PolarHBondContact O-N 3.01Å
487E49.9Very low45.3Very low161 Ų161123 Ų12375%0.75265%0.652SS**THydrogen-bonded Turntrans-68.4-12.2-176.9-99.1-162.8137.700114.5R399R399-E487 IonicContact NH1-OE1 2.67Å; R399-E487 PolarHBondContact NH1-OE1 2.96Å
488D47.6Very low45.1Very low162 Ų162123 Ų12387%0.86666%0.658SS**THydrogen-bonded Turntrans-91-10.5-167.6-63-27.2000115.3D486D486-D488 PolarHBondContact O-N 3.01Å
489I47.4Very low45Very low108 Ų108122.2 Ų122.255%0.55466%0.661SS**SBendtrans-104.4-28.3-170-62176.9000113.4
490E48.6Very low44.9Very low127 Ų127125.2 Ų125.259%0.59367%0.671SS**Hα-helixtrans-80-22.3-169.8-71.8-158132.700115.6F492 I493 A494E490-F492 PolarHBondContact O-N 2.78Å; E490-I493 PolarHBondContact O-N 2.81Å; E490-I493 VanDerWaalsContact O-N 3.14Å; E490-A494 PolarHBondContact O-N 2.7Å
491E48.5Very low44.5Very low176 Ų176122.7 Ų122.782%0.82268%0.675SS**Hα-helixtrans-64.9-27179.5-168.6162.8-154.200112.3
492F39.8Very low44.3Very low173 Ų173123.9 Ų123.976%0.75968%0.681SS**Hα-helixtrans-76.6-26.5176.1-164.4-104.5000113.6E490 S495 S496E490-F492 PolarHBondContact O-N 2.78Å; F492-S495 PolarHBondContact O-OG 2.91Å; F492-S495 VanDerWaalsContact O-OG 3.13Å; F492-S496 PolarHBondContact O-OG 3.18Å
493I50.9Low43.9Very low92 Ų92127.2 Ų127.247%0.47269%0.689SS.*Hα-helixtrans-86.1-29-178.3-58.7179000111.1E490 S495 S496 N497E490-I493 PolarHBondContact O-N 2.81Å; E490-I493 VanDerWaalsContact O-N 3.14Å; I493-S495 VanDerWaalsContact C-N 3.33Å; I493-S495 PolarHBondContact O-N 3.17Å; I493-S496 PolarHBondContact O-OG 2.71Å; I493-S496 VanDerWaalsContact O-OG 3.09Å; I493-N497 PolarHBondContact O-ND2 2.97Å
494A46.2Very low43.5Very low65 Ų65127.6 Ų127.654%0.53769%0.69SS.*Hα-helixtrans-67.5-31177.400000113.4E490E490-A494 PolarHBondContact O-N 2.7Å
495S48.3Very low43.1Very low74 Ų74135.7 Ų135.752%0.51771%0.709SS.*Hα-helixtrans-79.2-37.6-178.857.70000113.3F492 I493 I498F492-S495 PolarHBondContact O-OG 2.91Å; F492-S495 VanDerWaalsContact O-OG 3.13Å; I493-S495 VanDerWaalsContact C-N 3.33Å; I493-S495 PolarHBondContact O-N 3.17Å; S495-I498 PolarHBondContact O-N 2.91Å
496S44Very low42.4Very low64 Ų64131.6 Ų131.645%0.44870%0.703SS.*Hα-helixtrans-67.2-37.7179.846.80000113.3F492 I493 I498 A499F492-S496 PolarHBondContact O-OG 3.18Å; I493-S496 PolarHBondContact O-OG 2.71Å; I493-S496 VanDerWaalsContact O-OG 3.09Å; S496-I498 PolarHBondContact O-N 2.77Å; S496-I498 VanDerWaalsContact O-N 3.16Å; S496-A499 PolarHBondContact O-N 3.06Å
497N42.3Very low41.6Very low121 Ų121130.8 Ų130.865%0.64771%0.712SS**THydrogen-bonded Turntrans-71.5-5.5-179-77.2-81.6000115I493I493-N497 PolarHBondContact O-ND2 2.97Å
498I43.1Very low40.6Very low142 Ų142131.1 Ų131.173%0.72871%0.711SS**THydrogen-bonded Turntrans-89.3-17.3176.7-65175.4000111.7S495 S496S495-I498 PolarHBondContact O-N 2.91Å; S496-I498 PolarHBondContact O-N 2.77Å; S496-I498 VanDerWaalsContact O-N 3.16Å
499A42.2Very low39.7Very low77 Ų77128.2 Ų128.264%0.63671%0.71SS**G310 helixtrans-78-34.2-175.200000114.7S496 G501S496-A499 PolarHBondContact O-N 3.06Å; A499-G501 PolarHBondContact O-N 2.82Å; A499-G501 VanDerWaalsContact O-N 3.13Å
500D41.6Very low38.8Very low164 Ų164129.4 Ų129.488%0.87771%0.713SS**G310 helixtrans-8010.8-171-88.4-25.3000115.3
501G40Very low37.8Very low69 Ų69129 Ų12971%0.71172%0.719SS**G310 helixtrans-86.8-12.3-174.700000116.9A499A499-G501 PolarHBondContact O-N 2.82Å; A499-G501 VanDerWaalsContact O-N 3.13Å
502I38.7Very low36.8Very low155 Ų155128.4 Ų128.480%0.79572%0.721SS**  trans-106.8105.5-166.5-57.9-179.4000112.5L504I502-L504 PolarHBondContact O-N 2.87Å
503K30.2Very low36.3Very low201 Ų201123.9 Ų123.987%0.87472%0.724SS**  trans-68.4115.7-178.2-169.9174.1-173.2171.60112.6
504L33.1Very low35.5Very low154 Ų154126.8 Ų126.881%0.80675%0.746SS**  trans-50.4140.5172.5-101.283.5000113.1I502I502-L504 PolarHBondContact O-N 2.87Å
505R31.2Very low34.8Very low247 Ų247128.5 Ų128.593%0.93276%0.761SS**  trans-112.7123.9144.4-97.8-175172.3135.8-2.3108.6
506S29.5Very low34.1Very low113 Ų113134.2 Ų134.279%0.7978%0.776SS**  trans-71.9136.2-178.8-175.20000111.5
507A30.1Very low34.4Very low101 Ų101136 Ų13684%0.83579%0.786SS**  trans-138.1127.4156.800000107.9
508K30.2Very low34.5Very low168 Ų168136 Ų13673%0.7379%0.793SS**  trans-92.1134.9-173.4-179.4-171.1177-161.50110.5E510K508-E510 WeakPolarHBondContact CE-OE1 3.48Å; K508-E510 IonicContact NZ-OE1 3.93Å; K508-E510 PolarHBondContact NZ-OE1 2.89Å
509A27.7Very low34.5Very low101 Ų101138 Ų13884%0.83580%0.799SS**  trans-147.2151.9158.400000109
510E28.1Very low34.5Very low134 Ų134140.4 Ų140.463%0.62681%0.806SS**  trans-114167-160.6-63178.2154.300114.6K508K508-E510 WeakPolarHBondContact CE-OE1 3.48Å; K508-E510 IonicContact NZ-OE1 3.93Å; K508-E510 PolarHBondContact NZ-OE1 2.89Å
511T28.4Very low34.8Very low117 Ų117137.5 Ų137.572%0.71879%0.79SS**  trans83.3123.5151.754.40000123.3
512N26.3Very low35.5Very low164 Ų164138.2 Ų138.288%0.87778%0.783SS**  trans77.2124.4137.9-66.1-4000122.1
513G30Very low36.3Very low79 Ų79136.1 Ų136.181%0.81477%0.773SS**  trans163.990.2163.100000113.7
514T34.6Very low37.5Very low153 Ų153133.8 Ų133.894%0.93977%0.765SS**  trans-84122.1176-53.60000111.4
515A30.4Very low38.6Very low101 Ų101131.5 Ų131.584%0.83575%0.754SS**  trans-158.7145.116100000113.2
516K33.7Very low40Very low194 Ų194125.1 Ų125.184%0.84374%0.738SS**  trans-145.6164.5168.7-143.8-150.2176.1-166.60105.5
517P50.5Low41.3Very low101 Ų101126.1 Ų126.166%0.65673%0.728SS**  cis-101.9-124.5-16.134.5-13.8000109.1
518P44.5Very low43.3Very low121 Ų121129.4 Ų129.479%0.78672%0.718SS**  cis-90.8-154.65.941-38.2000113.2
519E43.2Very low44.8Very low183 Ų183124.7 Ų124.786%0.85570%0.704SS**  trans-122144.7170.3-68.5167.2153.200107.8
520T43.3Very low46.6Very low129 Ų129127.8 Ų127.879%0.79170%0.701SS**  trans-86.3121.717943.70000111.1
521N48.1Very low48.3Very low103 Ų103127.2 Ų127.255%0.55170%0.702SS**  trans-91.1125.2179-132.94.8000109.2D523 E524N521-D523 PolarHBondContact O-N 3.17Å; N521-D523 VanDerWaalsContact O-N 3.1Å; N521-E524 PolarHBondContact O-N 3.42Å
522P54.3Low49.7Very low84 Ų84126 Ų12655%0.54569%0.692SS.*Hα-helixtrans-64.8-20.1-171.926.3-35.2000114E524 L526P522-E524 VanDerWaalsContact C-N 3.34Å; P522-E524 PolarHBondContact O-N 2.98Å; P522-L526 PolarHBondContact O-N 2.66Å
523D54.8Low50.9Low111 Ų111123.8 Ų123.859%0.59468%0.678SS**Hα-helixtrans-72.5-22.8179.7-56.4-33.6000113.3N521 K527N521-D523 PolarHBondContact O-N 3.17Å; N521-D523 VanDerWaalsContact O-N 3.1Å; D523-K527 PolarHBondContact O-N 2.83Å
524E55.5Low51.6Low151 Ų151124.2 Ų124.271%0.70667%0.667SS**Hα-helixtrans-79-36.6174.6-72.9-165.3130.600112.1N521 P522 K527 W528N521-E524 PolarHBondContact O-N 3.42Å; P522-E524 VanDerWaalsContact C-N 3.34Å; P522-E524 PolarHBondContact O-N 2.98Å; E524-K527 PolarHBondContact O-N 3.36Å; E524-W528 PolarHBondContact O-N 2.95Å
525D56.4Low52.3Low106 Ų106122.8 Ų122.857%0.56766%0.663SS**Hα-helixtrans-65.8-40.3176-76-24.1000111.4K527 W528 V529D525-K527 VanDerWaalsContact C-N 3.3Å; D525-K527 PolarHBondContact O-N 2.82Å; D525-W528 PolarHBondContact O-N 2.04Å; D525-V529 WeakPolarHBondContact O-CG2 3.48Å; D525-V529 PolarHBondContact O-N 2.86Å
526L60.2Low53.1Low114 Ų114122.4 Ų122.460%0.59765%0.654SS**Hα-helixtrans-59.4-41.6173.3-74.3170.2000111.9P522 V529 E530P522-L526 PolarHBondContact O-N 2.66Å; L526-V529 WeakPolarHBondContact O-CB 3.07Å; L526-V529 PolarHBondContact O-N 2.83Å; L526-E530 PolarHBondContact O-N 2.88Å; L526-E530 VanDerWaalsContact O-N 3.14Å
527K58Low53.6Low134 Ų134120.4 Ų120.458%0.58365%0.652SS**Hα-helixtrans-68.7-36.1178.8-167.3176.2-180-176.70112.6D523 E524 D525 V529 E530 D531D523-K527 PolarHBondContact O-N 2.83Å; E524-K527 PolarHBondContact O-N 3.36Å; D525-K527 VanDerWaalsContact C-N 3.3Å; D525-K527 PolarHBondContact O-N 2.82Å; K527-V529 VanDerWaalsContact C-N 3.3Å; K527-V529 PolarHBondContact O-N 2.86Å; K527-E530 PolarHBondContact O-N 3Å; K527-D531 WeakPolarHBondContact O-CB 3.49Å; K527-D531 PolarHBondContact O-N 3.2Å
528W70.9Confident53.3Low169 Ų169121.8 Ų121.864%0.6466%0.658SS**Hα-helixtrans-60.7-40.1172.9-17988.7000111.9E524 D525 N532E524-W528 PolarHBondContact O-N 2.95Å; D525-W528 PolarHBondContact O-N 2.04Å; W528-N532 HydrophobicContact CZ2-CB 4.37Å; W528-N532 PolarHBondContact NE1-ND2 2.93Å; W528-N532 WeakPolarHBondContact O-CB 3.37Å; W528-N532 PolarHBondContact O-N 3.23Å; W528-N532 VanDerWaalsContact O-N 3.13Å; W528-N532 PolarHBondContact O-ND2 3.23Å
529V61.2Low53.3Low69 Ų69123.3 Ų123.342%0.41866%0.66SS.*Hα-helixtrans-63.6-43.1176.1174.20000111.3D525 L526 K527 N532 I533D525-V529 WeakPolarHBondContact O-CG2 3.48Å; D525-V529 PolarHBondContact O-N 2.86Å; L526-V529 WeakPolarHBondContact O-CB 3.07Å; L526-V529 PolarHBondContact O-N 2.83Å; K527-V529 VanDerWaalsContact C-N 3.3Å; K527-V529 PolarHBondContact O-N 2.86Å; V529-N532 PolarHBondContact O-N 2.88Å; V529-I533 HydrophobicContact CG1-CD1 3.65Å; V529-I533 HydrophobicContact CG1-CG1 4.41Å; V529-I533 WeakPolarHBondContact O-CG1 3.36Å; V529-I533 PolarHBondContact O-N 2.64Å
530E66.4Low53.4Low166 Ų166121.1 Ų121.178%0.77666%0.659SS**Hα-helixtrans-70.8-32.7-178.3-154.7158.7-14600112.8L526 K527L526-E530 PolarHBondContact O-N 2.88Å; L526-E530 VanDerWaalsContact O-N 3.14Å; K527-E530 PolarHBondContact O-N 3Å
531D64.6Low53.3Low123 Ų123119 Ų11966%0.65866%0.655SS**Hα-helixtrans-80.7-19.1175.9-77.9-29.5000114K527K527-D531 WeakPolarHBondContact O-CB 3.49Å; K527-D531 PolarHBondContact O-N 3.2Å
532N57.8Low52.7Low92 Ų92120.4 Ų120.449%0.49266%0.661SS.*Hα-helixtrans-111.5-8.7-173.5-71.7-93.6000115.6W528 V529 P534W528-N532 HydrophobicContact CZ2-CB 4.37Å; W528-N532 PolarHBondContact NE1-ND2 2.93Å; W528-N532 WeakPolarHBondContact O-CB 3.37Å; W528-N532 PolarHBondContact O-N 3.23Å; W528-N532 VanDerWaalsContact O-N 3.13Å; W528-N532 PolarHBondContact O-ND2 3.23Å; V529-N532 PolarHBondContact O-N 2.88Å; N532-P534 WeakPolarHBondContact O-CD 3.25Å
533I50.5Low51.9Low116 Ų116122.1 Ų122.160%0.59567%0.673SS**SBendtrans-95.6110.5171.7-62179.1000109.4V529 S535V529-I533 HydrophobicContact CG1-CD1 3.65Å; V529-I533 HydrophobicContact CG1-CG1 4.41Å; V529-I533 WeakPolarHBondContact O-CG1 3.36Å; V529-I533 PolarHBondContact O-N 2.64Å; I533-S535 PolarHBondContact O-N 3.23Å
534P45.3Very low51.4Low88 Ų88122.3 Ų122.357%0.57168%0.678SS**  trans-66.5125.3178.226.3-33.2000111.1N532 S536N532-P534 WeakPolarHBondContact O-CD 3.25Å; P534-S536 PolarHBondContact O-N 3.35Å
535S49.8Very low50.8Low124 Ų124120.6 Ų120.687%0.86767%0.673SS**SBendtrans-75.141.2-174.2460000114.7I533I533-S535 PolarHBondContact O-N 3.23Å
536S47.1Very low50.1Low92 Ų92123.1 Ų123.164%0.64369%0.686SS**  trans-13420-173.765.60000115.7P534P534-S536 PolarHBondContact O-N 3.35Å
537L43.8Very low49.4Very low152 Ų152123.6 Ų123.680%0.79669%0.689SS**  trans-109.86.8178-81.4173.3000115.5
538T44.3Very low49.3Very low130 Ų130120 Ų12080%0.79868%0.68SS**SBendtrans-82.4-7.4178.541.70000115.4
539D43.4Very low48.6Very low153 Ų153117.3 Ų117.382%0.81868%0.678SS**SBendtrans-112.66.2-165.1-91.5-24.8000117.2
540V46.7Very low48.6Very low137 Ų137120.5 Ų120.583%0.8369%0.689SS**SBendtrans-128.120.4-173.5-160.30000114.4
541A39.2Very low48.3Very low86 Ų86119.2 Ų119.271%0.71168%0.683SS**  trans-139.548.3179.400000114.7
542L36.6Very low48.3Very low131 Ų131117.1 Ų117.169%0.68667%0.671SS**  trans-126.4103167.6-129.977.8000111.6L545L542-L545 HydrophobicContact CD1-CD1 3.81Å; L542-L545 HydrophobicContact CD1-CG 3.9Å; L542-L545 HydrophobicContact CD2-CB 4.4Å; L542-L545 HydrophobicContact CD2-CD1 4.32Å; L542-L545 HydrophobicContact CG-CB 4.46Å; L542-L545 HydrophobicContact CG-CD1 4.44Å; L542-L545 HydrophobicContact CG-CG 4.31Å
543P38.1Very low48.6Very low121 Ų121119.6 Ų119.679%0.78668%0.681SS**SBendtrans-13937.9131.839.9-28.7000112.6
544V44Very low49.4Very low115 Ų115117.6 Ų117.670%0.69767%0.674SS**SBendtrans-115.6-16.3-177.7177.70000113.8L546V544-L546 VanDerWaalsContact C-N 3.28Å; V544-L546 PolarHBondContact O-N 3Å
545L42.6Very low50.4Low114 Ų114117.3 Ų117.360%0.59767%0.671SS**THydrogen-bonded Turntrans-8210.3-178.8-64.7-170.2000115.6L542L542-L545 HydrophobicContact CD1-CD1 3.81Å; L542-L545 HydrophobicContact CD1-CG 3.9Å; L542-L545 HydrophobicContact CD2-CB 4.4Å; L542-L545 HydrophobicContact CD2-CD1 4.32Å; L542-L545 HydrophobicContact CG-CB 4.46Å; L542-L545 HydrophobicContact CG-CD1 4.44Å; L542-L545 HydrophobicContact CG-CG 4.31Å
546L42.4Very low51.3Low160 Ų160118.6 Ų118.684%0.83866%0.661SS**THydrogen-bonded Turntrans-91.4-13.9175.8-75.8174.3000114.6V544V544-L546 VanDerWaalsContact C-N 3.28Å; V544-L546 PolarHBondContact O-N 3Å
547D44.9Very low52.6Low124 Ų124121.5 Ų121.566%0.66366%0.659SS**SBendtrans-81.2-23173.6-106.1-15000112.4D549 E551D547-D549 PolarHBondContact O-N 3.09Å; D547-E551 PolarHBondContact O-N 3.11Å
548S55.3Low54Low57 Ų57119.2 Ų119.240%0.39964%0.644SS.*Hα-helixtrans-69.1-36.4-171.5-172.40000113.8I552S548-I552 WeakPolarHBondContact O-CD1 3.49Å; S548-I552 VanDerWaalsContact O-CG1 3.23Å; S548-I552 WeakPolarHBondContact O-CG1 3.38Å; S548-I552 PolarHBondContact O-N 3.5Å
549D56.7Low55.1Low113 Ų113119.7 Ų119.760%0.60464%0.639SS**Hα-helixtrans-78.9-26.4-175.6-78.8-20.3000112.3D547 M553D547-D549 PolarHBondContact O-N 3.09Å; D549-M553 WeakPolarHBondContact O-CB 3.16Å; D549-M553 WeakPolarHBondContact O-CG 3.43Å; D549-M553 PolarHBondContact O-N 3.11Å
550E61.5Low56.2Low137 Ų137115.8 Ų115.864%0.6462%0.624SS**Hα-helixtrans-74-37.6175.4-166.5165.3-165.700111.5M553 T554E550-M553 PolarHBondContact O-N 3.35Å; E550-T554 WeakPolarHBondContact O-CB 3.5Å; E550-T554 WeakPolarHBondContact O-CG2 3.25Å; E550-T554 PolarHBondContact O-N 3.32Å; E550-T554 PolarHBondContact O-OG1 2.92Å
551E59.3Low56.9Low139 Ų139115.1 Ų115.165%0.6561%0.61SS**Hα-helixtrans-66.6-37.7171.1-70.8-160.3144.500112.7D547 T554 T555D547-E551 PolarHBondContact O-N 3.11Å; E551-T554 WeakPolarHBondContact CA-OG1 3.41Å; E551-T554 PolarHBondContact O-OG1 2.98Å; E551-T555 WeakPolarHBondContact O-CB 3.48Å; E551-T555 VanDerWaalsContact O-CG2 3.3Å; E551-T555 WeakPolarHBondContact O-CG2 3.13Å; E551-T555 PolarHBondContact O-N 3.38Å; E551-T555 PolarHBondContact O-OG1 3.45Å
552I65.8Low57.9Low79 Ų79118.3 Ų118.341%0.40561%0.614SS.*Hα-helixtrans-70.3-33.4177-67.2166.3000111.8S548 T555 K556S548-I552 WeakPolarHBondContact O-CD1 3.49Å; S548-I552 VanDerWaalsContact O-CG1 3.23Å; S548-I552 WeakPolarHBondContact O-CG1 3.38Å; S548-I552 PolarHBondContact O-N 3.5Å; I552-T555 WeakPolarHBondContact CA-OG1 3.31Å; I552-T555 PolarHBondContact O-OG1 2.97Å; I552-K556 WeakPolarHBondContact O-CG 3.37Å; I552-K556 PolarHBondContact O-N 2.79Å
553M63.4Low58.5Low144 Ų144123.4 Ų123.471%0.70963%0.634SS**Hα-helixtrans-71.9-43.7174.2-73.7-100-80.800112.2D549 E550 K556 Y557D549-M553 WeakPolarHBondContact O-CB 3.16Å; D549-M553 WeakPolarHBondContact O-CG 3.43Å; D549-M553 PolarHBondContact O-N 3.11Å; E550-M553 PolarHBondContact O-N 3.35Å; M553-K556 PolarHBondContact O-N 2.77Å; M553-Y557 WeakPolarHBondContact O-CB 3.42Å; M553-Y557 PolarHBondContact O-N 2.95Å
554T66.4Low59.5Low74 Ų74123.5 Ų123.545%0.45463%0.627SS.*Hα-helixtrans-69.3-39179.549.50000112.4E550 E551 Y557 E558E550-T554 WeakPolarHBondContact O-CB 3.5Å; E550-T554 WeakPolarHBondContact O-CG2 3.25Å; E550-T554 PolarHBondContact O-N 3.32Å; E550-T554 PolarHBondContact O-OG1 2.92Å; E551-T554 WeakPolarHBondContact CA-OG1 3.41Å; E551-T554 PolarHBondContact O-OG1 2.98Å; T554-Y557 PolarHBondContact O-N 3.48Å; T554-E558 PolarHBondContact O-N 2.62Å
555T67.3Low60.3Low82 Ų82123.9 Ų123.950%0.50362%0.623SS.*Hα-helixtrans-64.3-41.6174.148.40000112.6E551 I552 E558 M559E551-T555 WeakPolarHBondContact O-CB 3.48Å; E551-T555 VanDerWaalsContact O-CG2 3.3Å; E551-T555 WeakPolarHBondContact O-CG2 3.13Å; E551-T555 PolarHBondContact O-N 3.38Å; E551-T555 PolarHBondContact O-OG1 3.45Å; I552-T555 WeakPolarHBondContact CA-OG1 3.31Å; I552-T555 PolarHBondContact O-OG1 2.97Å; T555-E558 PolarHBondContact O-N 3.06Å; T555-M559 WeakPolarHBondContact O-CG 3.41Å; T555-M559 PolarHBondContact O-N 3.11Å
556K68.6Low61.3Low151 Ų151124.5 Ų124.566%0.65762%0.624SS**Hα-helixtrans-63.6-38.7171.9-79.8-179177.6174.10112.7I552 M553 M559 S560I552-K556 WeakPolarHBondContact O-CG 3.37Å; I552-K556 PolarHBondContact O-N 2.79Å; M553-K556 PolarHBondContact O-N 2.77Å; K556-M559 PolarHBondContact O-N 3.26Å; K556-S560 PolarHBondContact O-N 3.46Å
557Y73.4Confident62.4Low152 Ų152122.4 Ų122.460%0.59661%0.612SS**Hα-helixtrans-65.4-44.4177.4-170.7-100.9000112.1M553 T554 S560M553-Y557 WeakPolarHBondContact O-CB 3.42Å; M553-Y557 PolarHBondContact O-N 2.95Å; T554-Y557 PolarHBondContact O-N 3.48Å; Y557-S560 PolarHBondContact O-N 3.2Å; Y557-S560 PolarHBondContact O-OG 3.18Å
558E73.8Confident63.5Low105 Ų105122.3 Ų122.349%0.49161%0.609SS.*Hα-helixtrans-67.2-36.2175.8-72.9-66.3115.800112.4T554 T555 S560 K561T554-E558 PolarHBondContact O-N 2.62Å; T555-E558 PolarHBondContact O-N 3.06Å; E558-S560 VanDerWaalsContact C-N 3.32Å; E558-S560 PolarHBondContact O-N 3.2Å; E558-K561 PolarHBondContact O-N 3.14Å; E558-K561 IonicContact OE1-NZ 2.59Å; E558-K561 PolarHBondContact OE1-NZ 3.42Å
559M67.3Low64Low140 Ų140126.7 Ų126.769%0.6962%0.623SS**Hα-helixtrans-62.6-37.3171.1-78.2-151.369.900112.7T555 K556 K561 L562T555-M559 WeakPolarHBondContact O-CG 3.41Å; T555-M559 PolarHBondContact O-N 3.11Å; K556-M559 PolarHBondContact O-N 3.26Å; M559-K561 PolarHBondContact O-N 3.17Å; M559-K561 VanDerWaalsContact O-N 3.17Å; M559-L562 PolarHBondContact O-N 2.88Å; M559-L562 VanDerWaalsContact O-N 3.1Å
560S67Low64.6Low71 Ų71127.6 Ų127.650%0.49762%0.624SS.*THydrogen-bonded Turntrans-70.8-4.8178.374.20000115.1K556 Y557 E558K556-S560 PolarHBondContact O-N 3.46Å; Y557-S560 PolarHBondContact O-N 3.2Å; Y557-S560 PolarHBondContact O-OG 3.18Å; E558-S560 VanDerWaalsContact C-N 3.32Å; E558-S560 PolarHBondContact O-N 3.2Å
561K61.9Low64.8Low122 Ų122126.9 Ų126.953%0.5362%0.623SS.*THydrogen-bonded Turntrans-90.4-6.2170.2-78.1176.8-178.8161.50113.9E558 M559E558-K561 PolarHBondContact O-N 3.14Å; E558-K561 IonicContact OE1-NZ 2.59Å; E558-K561 PolarHBondContact OE1-NZ 3.42Å; M559-K561 PolarHBondContact O-N 3.17Å; M559-K561 VanDerWaalsContact O-N 3.17Å
562L60.5Low65.3Low154 Ų154125.9 Ų125.981%0.80662%0.62SS**  trans-108.8-3.7-174.9-65.8166.4000113.4M559M559-L562 PolarHBondContact O-N 2.88Å; M559-L562 VanDerWaalsContact O-N 3.1Å
563E47.8Very low65.2Low237 Ų237130.2 Ų130.2100%1.10764%0.64SS**  trans-94.30158.2-69.5-171.2133.200110.7

Retrieved 563 of 563 residues in 95.1 ms (Link to these results)