A0A087YDF9_POEFO Loading...

Solute carrier family 11 member 2

AlphaFold DB , UniProt , Accession A0A087YDF9, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 562 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.6	Very low	28.7	Very low	240 Å²	240	150.8 Å²	150.8	100%	1.182	84%	0.842	S	S	*	*				0	109.3	0	-80.8	166.6	168.6	0	0	107.2
2	T	30.2	Very low	28.5	Very low	145 Å²	145	153.8 Å²	153.8	89%	0.89	84%	0.844	S	S	*	*			trans	9.8	135.4	148.8	45.2	0	0	0	0	117.6
3	G	27.2	Very low	28.4	Very low	75 Å²	75	152.1 Å²	152.1	77%	0.773	83%	0.834	S	S	*	*			cis	121.8	108.5	25.3	0	0	0	0	0	109.9
4	Q	27.7	Very low	28.8	Very low	180 Å²	180	148.8 Å²	148.8	84%	0.841	82%	0.823	S	S	*	*			trans	19.5	149	152.1	-100.5	166.4	-39.3	0	0	124.3
5	Q	28.8	Very low	28.5	Very low	176 Å²	176	152.4 Å²	152.4	82%	0.822	82%	0.82	S	S	*	*				118.6	139.5	124.1	-102.2	172.2	-11.3	0	0	121.6
6	N	32.1	Very low	28.2	Very low	163 Å²	163	153 Å²	153	87%	0.872	82%	0.816	S	S	*	*			trans	-51.8	163.4	168.6	-77.6	-10.4	0	0	0	115.4
7	G	26.5	Very low	28	Very low	78 Å²	78	153.6 Å²	153.6	80%	0.804	81%	0.813	S	S	*	*			trans	-167.4	117	157.1	0	0	0	0	0	113.5
8	D	27.7	Very low	27.9	Very low	153 Å²	153	152.9 Å²	152.9	82%	0.818	81%	0.809	S	S	*	*			trans	-72.1	-179.3	173.3	-72.1	-53.2	0	0	0	114.5
9	L	28.3	Very low	27.6	Very low	153 Å²	153	148.8 Å²	148.8	80%	0.801	81%	0.807	S	S	*	*			trans	130.9	138.2	147.2	-69.8	160.2	0	0	0	111
10	L	27.8	Very low	27.5	Very low	136 Å²	136	148.8 Å²	148.8	71%	0.712	81%	0.812	S	S	*	*			cis	-167.5	164	3.3	-92	159	0	0	0	104.9
11	E	25.4	Very low	27.4	Very low	160 Å²	160	150.9 Å²	150.9	75%	0.748	82%	0.816	S	S	*	*				174.4	120.2	60.4	-137.1	163.9	138.7	0	0	106.9
12	E	25.3	Very low	26.8	Very low	186 Å²	186	145.2 Å²	145.2	87%	0.869	80%	0.8	S	S	*	*				82.5	134.3	111.2	-72.2	-158.8	149	0	0	120.7
13	D	27.4	Very low	26.6	Very low	132 Å²	132	145.2 Å²	145.2	71%	0.706	80%	0.795	S	S	*	*			trans	-91.1	171.8	-172.1	-176.1	30.2	0	0	0	111.5	R15	D13-R15 PolarHBondContact OD1-N 3.27Å
14	P	34.3	Very low	26.5	Very low	106 Å²	106	149.3 Å²	149.3	69%	0.688	79%	0.794	S	S	*	*				-153.5	143.3	87.6	35	-13	0	0	0	117.7
15	R	24.5	Very low	26.4	Very low	203 Å²	203	150.5 Å²	150.5	77%	0.766	79%	0.792	S	S	*	*				46.9	152.5	125.9	-57.2	-175.4	-169.8	-179.7	4.9	119.8	D13	D13-R15 PolarHBondContact OD1-N 3.27Å
16	Q	23.9	Very low	26.2	Very low	162 Å²	162	148.2 Å²	148.2	76%	0.757	80%	0.795	S	S	*	*			cis	-175.4	148.3	3.4	-118.1	171.3	-44.5	0	0	105
17	E	25.1	Very low	25.9	Very low	164 Å²	164	145 Å²	145	77%	0.766	79%	0.791	S	S	*	*				160.8	130.3	123.5	-92.1	-160.4	134	0	0	115.4
18	N	25.2	Very low	26.1	Very low	140 Å²	140	148.9 Å²	148.9	75%	0.749	79%	0.792	S	S	*	*			trans	75.2	114.6	142.3	-58.3	-22.8	0	0	0	120.7
19	G	22.5	Very low	26	Very low	75 Å²	75	146.3 Å²	146.3	77%	0.773	79%	0.786	S	S	*	*			trans	-92.7	156.6	168.6	0	0	0	0	0	113.6
20	V	25.3	Very low	26.1	Very low	149 Å²	149	144.8 Å²	144.8	90%	0.903	79%	0.785	S	S	*	*			trans	-146.1	128.9	151.7	177.3	0	0	0	0	107.8
21	Q	25.3	Very low	26.1	Very low	192 Å²	192	144.1 Å²	144.1	90%	0.897	79%	0.789	S	S	*	*			trans	-70.6	137.9	171.6	-89.6	166.8	-33.2	0	0	112.1
22	S	23.4	Very low	26.3	Very low	121 Å²	121	141.1 Å²	141.1	85%	0.846	79%	0.791	S	S	*	*				-168.6	145.2	125.3	62.2	0	0	0	0	112.7
23	N	25.5	Very low	26.4	Very low	145 Å²	145	137.3 Å²	137.3	78%	0.775	79%	0.786	S	S	*	*			trans	-51.7	145.2	-172	-61.7	-36	0	0	0	116.3
24	H	24.1	Very low	26.6	Very low	162 Å²	162	137 Å²	137	75%	0.75	79%	0.791	S	S	*	*				178.7	126.9	122.3	-94.6	-48.3	0	0	0	113.3
25	Y	25.4	Very low	26.3	Very low	205 Å²	205	139.8 Å²	139.8	80%	0.804	80%	0.799	S	S	*	*			trans	41	101.6	155.7	-62.3	-79.7	0	0	0	119.3	A27	Y25-A27 PolarHBondContact O-N 3.46Å
26	S	25.2	Very low	26.5	Very low	127 Å²	127	134.4 Å²	134.4	89%	0.888	80%	0.798	S	S	*	*			trans	-65.9	101.3	157.1	-52	0	0	0	0	109.4	I28	S26-I28 PolarHBondContact O-N 3.29Å
27	A	26.9	Very low	26.6	Very low	96 Å²	96	135.7 Å²	135.7	79%	0.793	80%	0.804	S	S	*	*			trans	-69.9	113.9	169.7	0	0	0	0	0	109.2	Y25 S29	Y25-A27 PolarHBondContact O-N 3.46Å; A27-S29 PolarHBondContact O-N 3.06Å
28	I	28.8	Very low	26.9	Very low	159 Å²	159	136.4 Å²	136.4	82%	0.815	81%	0.807	S	S	*	*	P	Polyproline II helix	trans	-56.1	127.5	168.1	-68.3	159.9	0	0	0	108.4	S26	S26-I28 PolarHBondContact O-N 3.29Å
29	S	26.4	Very low	27.3	Very low	100 Å²	100	137.6 Å²	137.6	70%	0.699	81%	0.808	S	S	*	*	P	Polyproline II helix	trans	-51.4	130	170.2	-46.5	0	0	0	0	110.1	A27	A27-S29 PolarHBondContact O-N 3.06Å
30	P	29.6	Very low	28.1	Very low	120 Å²	120	138.5 Å²	138.5	78%	0.779	80%	0.801	S	S	*	*	P	Polyproline II helix	trans	-65.6	134.7	173.9	-4.9	16.8	0	0	0	109.1
31	P	29.2	Very low	28.6	Very low	122 Å²	122	138.3 Å²	138.3	79%	0.792	79%	0.788	S	S	*	*	P	Polyproline II helix	trans	-64.4	146.1	174.3	26.8	-31	0	0	0	109.8	S33	P31-S33 PolarHBondContact O-N 3.32Å
32	A	29.6	Very low	29.5	Very low	97 Å²	97	130.5 Å²	130.5	80%	0.802	76%	0.755	S	S	*	*	P	Polyproline II helix	trans	-46.8	130.2	173.7	0	0	0	0	0	110.4
33	S	27.1	Very low	30.7	Very low	107 Å²	107	126 Å²	126	75%	0.748	72%	0.722	S	S	*	*	P	Polyproline II helix	trans	-51.9	139.5	175.7	31.5	0	0	0	0	110.3	P31 L35	P31-S33 PolarHBondContact O-N 3.32Å; S33-L35 PolarHBondContact O-N 3.31Å
34	P	31.6	Very low	31.9	Very low	125 Å²	125	120.1 Å²	120.1	81%	0.812	69%	0.689	S	S	*	*	P	Polyproline II helix	trans	-60.8	132.7	174.1	-3.1	14.3	0	0	0	108.2	A36	P34-A36 PolarHBondContact O-N 3.29Å
35	L	28.4	Very low	33.5	Very low	164 Å²	164	113.1 Å²	113.1	86%	0.859	66%	0.657	S	S	*	*			trans	-35.5	128.8	165.5	-76.7	146.8	0	0	0	109.6	S33 Q37	S33-L35 PolarHBondContact O-N 3.31Å; L35-Q37 PolarHBondContact O-N 2.96Å
36	A	29	Very low	34.8	Very low	91 Å²	91	111.7 Å²	111.7	75%	0.752	66%	0.657	S	S	*	*			trans	-46.5	114.8	167.1	0	0	0	0	0	107.5	P34 E38	P34-A36 PolarHBondContact O-N 3.29Å; A36-E38 VanDerWaalsContact C-N 3.28Å; A36-E38 PolarHBondContact O-N 2.86Å
37	Q	25.3	Very low	36.5	Very low	189 Å²	189	113.9 Å²	113.9	88%	0.883	65%	0.654	S	S	*	*			trans	-59.6	102.7	166.1	-77.6	173.8	-22.9	0	0	105.6	L35 E39	L35-Q37 PolarHBondContact O-N 2.96Å; Q37-E39 PolarHBondContact O-N 2.98Å
38	E	31.5	Very low	38.7	Very low	178 Å²	178	114.6 Å²	114.6	83%	0.832	64%	0.636	S	S	*	*			trans	-54.7	106.3	161.8	-72	-178.9	162.4	0	0	105.9	A36 P40	A36-E38 VanDerWaalsContact C-N 3.28Å; A36-E38 PolarHBondContact O-N 2.86Å; E38-P40 WeakPolarHBondContact O-CD 3.28Å; E38-P40 VanDerWaalsContact O-N 3.12Å
39	E	33.5	Very low	41	Very low	165 Å²	165	108.1 Å²	108.1	77%	0.771	60%	0.603	S	S	*	*			trans	-63.1	109.9	164.2	-79.9	-151.1	160.3	0	0	107	Q37	Q37-E39 PolarHBondContact O-N 2.98Å
40	P	38.4	Very low	43.4	Very low	95 Å²	95	107.6 Å²	107.6	62%	0.617	60%	0.597	S	S	*	*			trans	-87.9	142.9	178.7	33.8	-21.4	0	0	0	108	E38	E38-P40 WeakPolarHBondContact O-CD 3.28Å; E38-P40 VanDerWaalsContact O-N 3.12Å
41	F	36.8	Very low	45.8	Very low	144 Å²	144	104 Å²	104	63%	0.632	57%	0.571	S	S	*	*			trans	100	89.4	166.2	-72.2	-96.9	0	0	0	118.2
42	S	44.6	Very low	48	Very low	28 Å²	28	99.8 Å²	99.8	20%	0.196	54%	0.544	C	S	.	.				-110.8	121.5	118.4	71.2	0	0	0	0	107.1	Y44 F45	S42-Y44 PolarHBondContact O-N 2.85Å; S42-F45 PolarHBondContact O-N 3.42Å; S42-F45 VanDerWaalsContact OG-CD2 3.31Å; S42-F45 WeakPolarHBondContact OG-CD2 3.31Å
43	T	48.7	Very low	50	Low	26 Å²	26	104.2 Å²	104.2	16%	0.16	55%	0.548	C	S	.	.	T	Hydrogen-bonded Turn	trans	-62.3	-4	-170.1	-33.4	0	0	0	0	114.7	Q389 E393 R402	T43-Q389 VanDerWaalsContact CB-NE2 3.33Å; T43-Q389 PolarHBondContact OG1-NE2 3.4Å; T43-E393 PolarHBondContact OG1-OE1 3.28Å; T43-R402 HydrophobicContact CG2-CG 3.91Å
44	Y	50.3	Low	51.7	Low	22 Å²	22	100.7 Å²	100.7	9%	0.086	52%	0.523	C	S	.	.	T	Hydrogen-bonded Turn	trans	-110.3	-22.8	179.1	-76.9	-66.7	0	0	0	115.5	S42 F190 D194 Y386 Q389 F390	S42-Y44 PolarHBondContact O-N 2.85Å; Y44-F190 HydrophobicContact CE1-CZ 4.48Å; Y44-D194 WeakPolarHBondContact CD1-OD1 3.47Å; Y44-D194 WeakPolarHBondContact CD1-OD2 3.48Å; Y44-D194 HydrophobicContact CE1-CB 4.47Å; Y44-D194 WeakPolarHBondContact CE1-OD1 3.33Å; Y44-D194 WeakPolarHBondContact CE1-OD2 3.4Å; Y44-Y386 HydrophobicContact CD1-CD1 4.39Å; Y44-Y386 AromaticContact CD1-CE1 3.49Å; Y44-Y386 HydrophobicContact CD1-CE1 3.49Å; Y44-Y386 VanDerWaalsContact CD1-CE1 3.49Å; Y44-Y386 AromaticContact CD2-CD1 3.68Å; Y44-Y386 HydrophobicContact CD2-CD1 3.68Å; Y44-Y386 AromaticContact CD2-CE1 3.59Å; Y44-Y386 HydrophobicContact CD2-CE1 3.59Å; Y44-Y386 HydrophobicContact CE1-CD1 4.14Å; Y44-Y386 AromaticContact CE1-CE1 3.34Å; Y44-Y386 HydrophobicContact CE1-CE1 3.34Å; Y44-Y386 AromaticContact CE1-CZ 3.97Å; Y44-Y386 AromaticContact CE2-CD1 3.35Å; Y44-Y386 HydrophobicContact CE2-CD1 3.35Å; Y44-Y386 AromaticContact CE2-CE1 3.41Å; Y44-Y386 HydrophobicContact CE2-CE1 3.41Å; Y44-Y386 VanDerWaalsContact CE2-CE1 3.41Å; Y44-Y386 HydrophobicContact CG-CD1 4.18Å; Y44-Y386 AromaticContact CG-CE1 3.61Å; Y44-Y386 HydrophobicContact CG-CE1 3.61Å; Y44-Y386 AromaticContact CZ-CD1 3.65Å; Y44-Y386 AromaticContact CZ-CE1 3.33Å; Y44-Q389 HydrophobicContact CE2-CB 4.24Å; Y44-Q389 HydrophobicContact CE2-CG 3.98Å; Y44-Q389 VanDerWaalsContact CZ-OE1 3.25Å; Y44-Q389 PolarHBondContact OH-OE1 2.91Å; Y44-F390 HydrophobicContact CD2-CZ 4.28Å
45	F	56.6	Low	52.7	Low	16 Å²	16	100.6 Å²	100.6	7%	0.07	52%	0.523	C	S	.	.			trans	-110.3	64.8	-177.5	-51.7	-54.4	0	0	0	109.4	S42 E47 R48 L198 S272 F390	S42-F45 PolarHBondContact O-N 3.42Å; S42-F45 VanDerWaalsContact OG-CD2 3.31Å; S42-F45 WeakPolarHBondContact OG-CD2 3.31Å; F45-E47 PolarHBondContact O-N 2.98Å; F45-R48 HydrophobicContact CB-CG 4.38Å; F45-L198 HydrophobicContact CD1-CD1 4.48Å; F45-L198 HydrophobicContact CD1-CD2 3.86Å; F45-L198 HydrophobicContact CE1-CD1 3.74Å; F45-L198 HydrophobicContact CE1-CD2 3.58Å; F45-L198 HydrophobicContact CE1-CG 4.22Å; F45-S272 VanDerWaalsContact CZ-CB 3.44Å; F45-F390 HydrophobicContact CE2-CZ 4.24Å; F45-F390 HydrophobicContact CZ-CZ 4.5Å
46	E	53.9	Low	54.1	Low	175 Å²	175	100.9 Å²	100.9	82%	0.818	53%	0.525	S	S	*	.	S	Bend	trans	-62.1	-28.5	167.8	-71.5	-179	-174	0	0	110.6
47	E	59.5	Low	55.6	Low	173 Å²	173	102.6 Å²	102.6	81%	0.808	52%	0.517	S	S	*	.	S	Bend	trans	-131.8	114.1	175.5	-154	172.3	-162.7	0	0	108.9	F45	F45-E47 PolarHBondContact O-N 2.98Å
48	R	74.1	Confident	57.5	Low	111 Å²	111	102 Å²	102	42%	0.419	52%	0.517	S	S	.	.	P	Polyproline II helix	trans	-83.4	150.3	176.2	-62.1	176.4	-174.5	170.8	4.8	109.2	F45 P50 E274	F45-R48 HydrophobicContact CB-CG 4.38Å; R48-P50 VanDerWaalsContact O-CD 3.28Å; R48-P50 WeakPolarHBondContact O-CD 3.3Å; R48-E274 HydrophobicContact CB-CG 3.23Å; R48-E274 HydrophobicContact CG-CG 4.16Å
49	V	76.8	Confident	59.9	Low	22 Å²	22	96.8 Å²	96.8	13%	0.133	49%	0.492	C	S	.	.	B	Isolated β-bridge	trans	-78.6	118.1	-179.6	-179.1	0	0	0	0	109.2	L198 R199 S272 E274	V49-L198 HydrophobicContact CG2-CD2 4.46Å; V49-R199 HydrophobicContact CG2-CG 4.43Å; V49-S272 PolarHBondContact N-O 3.32Å; V49-S272 VanDerWaalsContact N-O 3.12Å; V49-E274 PolarHBondContact O-N 3.38Å
50	P	77.2	Confident	62.4	Low	89 Å²	89	89.7 Å²	89.7	58%	0.578	46%	0.46	S	S	*	.	P	Polyproline II helix	trans	-71.5	141.1	178.7	29.2	-34.6	0	0	0	110.6	R48	R48-P50 VanDerWaalsContact O-CD 3.28Å; R48-P50 WeakPolarHBondContact O-CD 3.3Å
51	I	79.8	Confident	64.6	Low	45 Å²	45	92.8 Å²	92.8	23%	0.231	46%	0.464	C	S	.	.	P	Polyproline II helix	trans	-89.9	128.7	179.3	-57.4	173.8	0	0	0	109.1	E53 K63 F67 E274 V275	I51-E53 PolarHBondContact O-N 3.43Å; I51-K63 HydrophobicContact CG2-CG 4.44Å; I51-F67 HydrophobicContact CD1-CE1 3.73Å; I51-F67 HydrophobicContact CD1-CE2 3.82Å; I51-F67 HydrophobicContact CD1-CZ 3.2Å; I51-F67 HydrophobicContact CG1-CE2 4.33Å; I51-F67 HydrophobicContact CG1-CZ 4.09Å; I51-F67 HydrophobicContact CG2-CE2 4.05Å; I51-F67 HydrophobicContact CG2-CZ 4.47Å; I51-E274 WeakPolarHBondContact CD1-O 3.48Å; I51-E274 WeakPolarHBondContact CG1-O 3.36Å; I51-V275 HydrophobicContact CD1-CG2 4.11Å
52	P	75.3	Confident	66.9	Low	34 Å²	34	95.1 Å²	95.1	22%	0.221	47%	0.469	C	S	.	.	P	Polyproline II helix	trans	-66	124.4	175.2	25.4	-31.3	0	0	0	110.8	S54 R62 K63 A66	P52-S54 PolarHBondContact O-N 3.24Å; P52-R62 HydrophobicContact CG-CG 4.2Å; P52-K63 HydrophobicContact CG-CG 4.18Å; P52-K63 WeakPolarHBondContact O-CE 3.06Å; P52-A66 HydrophobicContact CG-CB 4.26Å
53	E	70.9	Confident	68.8	Low	190 Å²	190	94.5 Å²	94.5	89%	0.888	46%	0.463	S	S	*	.	P	Polyproline II helix	trans	-68.3	124.2	169.9	-66.3	-172.8	-179.4	0	0	109.8	I51	I51-E53 PolarHBondContact O-N 3.43Å
54	S	63.7	Low	70.7	Confident	32 Å²	32	94.2 Å²	94.2	22%	0.224	46%	0.46	C	S	.	.			trans	-126.8	108	171.4	65.5	0	0	0	0	108.4	P52 N56 K63	P52-S54 PolarHBondContact O-N 3.24Å; S54-N56 PolarHBondContact O-N 3.42Å; S54-K63 WeakPolarHBondContact OG-CE 3.37Å
55	P	52.9	Low	72.4	Confident	123 Å²	123	102 Å²	102	80%	0.799	49%	0.489	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.3	128.8	178.7	25.5	-30.1	0	0	0	109.8
56	N	56.6	Low	73.8	Confident	170 Å²	170	101.7 Å²	101.7	91%	0.909	49%	0.489	S	S	*	.	T	Hydrogen-bonded Turn	trans	60.5	48.7	166.7	-67.8	-16.5	0	0	0	118.6	S54	S54-N56 PolarHBondContact O-N 3.42Å
57	Q	60.8	Low	75.3	Confident	127 Å²	127	93.5 Å²	93.5	59%	0.593	45%	0.451	S	S	*	.			trans	-123.9	133.2	161.5	-103	176.2	-7.5	0	0	111.8	F59	Q57-F59 PolarHBondContact O-N 2.87Å
58	M	66	Low	76.7	Confident	176 Å²	176	86.5 Å²	86.5	87%	0.867	42%	0.42	S	S	*	.	S	Bend	trans	-68.6	-19.1	179.4	-162.5	-174.5	-95	0	0	112.5	K288	M58-K288 PolarHBondContact O-NZ 2.75Å
59	F	80.9	Confident	77.5	Confident	70 Å²	70	81.3 Å²	81.3	31%	0.307	40%	0.402	S	S	.	.			trans	-157.5	139	176.5	179.7	-101.3	0	0	0	110.3	Q57 F61 L64 Y289 I292	Q57-F59 PolarHBondContact O-N 2.87Å; F59-F61 HydrophobicContact CD1-CD2 4.5Å; F59-F61 HydrophobicContact CD1-CE2 4.37Å; F59-F61 AromaticContact CE1-CD1 3.97Å; F59-F61 HydrophobicContact CE1-CD1 3.97Å; F59-F61 AromaticContact CE1-CD2 3.93Å; F59-F61 HydrophobicContact CE1-CD2 3.93Å; F59-F61 AromaticContact CE1-CE1 3.81Å; F59-F61 HydrophobicContact CE1-CE1 3.81Å; F59-F61 AromaticContact CE1-CE2 3.77Å; F59-F61 HydrophobicContact CE1-CE2 3.77Å; F59-F61 HydrophobicContact CE1-CG 4.03Å; F59-F61 AromaticContact CE1-CZ 3.71Å; F59-F61 HydrophobicContact CE1-CZ 3.71Å; F59-F61 HydrophobicContact CZ-CD1 4.3Å; F59-F61 HydrophobicContact CZ-CE1 4.2Å; F59-F61 HydrophobicContact CZ-CZ 4.49Å; F59-L64 HydrophobicContact CE2-CD2 4.45Å; F59-L64 HydrophobicContact CZ-CD2 3.97Å; F59-Y289 AromaticContact CD2-CE1 3.91Å; F59-Y289 HydrophobicContact CD2-CE1 3.91Å; F59-Y289 AromaticContact CE2-CE1 3.96Å; F59-Y289 HydrophobicContact CE2-CE1 3.96Å; F59-I292 HydrophobicContact CD2-CD1 4.37Å; F59-I292 HydrophobicContact CE2-CD1 4.01Å
60	S	85.9	Confident	78.1	Confident	15 Å²	15	80.3 Å²	80.3	11%	0.105	40%	0.396	C	S	.	.			trans	-137.5	124.8	176.8	172.1	0	0	0	0	111	R62 K63 L64 Y289	S60-R62 VanDerWaalsContact C-N 3.26Å; S60-R62 PolarHBondContact O-N 3.37Å; S60-R62 PolarHBondContact OG-N 3.07Å; S60-K63 PolarHBondContact O-N 3.22Å; S60-K63 PolarHBondContact OG-N 3.3Å; S60-L64 PolarHBondContact O-N 3.08Å; S60-Y289 PolarHBondContact N-OH 3.48Å
61	F	85.7	Confident	78.9	Confident	160 Å²	160	76.1 Å²	76.1	70%	0.702	37%	0.368	S	S	*	.	H	α-helix	trans	-64.2	-31.6	175.6	-74.9	-79.5	0	0	0	112.5	F59 L64 W65	F59-F61 HydrophobicContact CD1-CD2 4.5Å; F59-F61 HydrophobicContact CD1-CE2 4.37Å; F59-F61 AromaticContact CE1-CD1 3.97Å; F59-F61 HydrophobicContact CE1-CD1 3.97Å; F59-F61 AromaticContact CE1-CD2 3.93Å; F59-F61 HydrophobicContact CE1-CD2 3.93Å; F59-F61 AromaticContact CE1-CE1 3.81Å; F59-F61 HydrophobicContact CE1-CE1 3.81Å; F59-F61 AromaticContact CE1-CE2 3.77Å; F59-F61 HydrophobicContact CE1-CE2 3.77Å; F59-F61 HydrophobicContact CE1-CG 4.03Å; F59-F61 AromaticContact CE1-CZ 3.71Å; F59-F61 HydrophobicContact CE1-CZ 3.71Å; F59-F61 HydrophobicContact CZ-CD1 4.3Å; F59-F61 HydrophobicContact CZ-CE1 4.2Å; F59-F61 HydrophobicContact CZ-CZ 4.49Å; F61-L64 PolarHBondContact O-N 3.14Å; F61-W65 WeakPolarHBondContact O-CB 3.07Å; F61-W65 PolarHBondContact O-N 2.88Å
62	R	85.1	Confident	79.4	Confident	194 Å²	194	76.3 Å²	76.3	73%	0.732	37%	0.367	S	S	*	.	H	α-helix	trans	-66.7	-40.1	175.4	-172	-179.9	178.5	-177.9	-0.9	111.3	P52 S60 A66	P52-R62 HydrophobicContact CG-CG 4.2Å; S60-R62 VanDerWaalsContact C-N 3.26Å; S60-R62 PolarHBondContact O-N 3.37Å; S60-R62 PolarHBondContact OG-N 3.07Å; R62-A66 PolarHBondContact O-N 3.31Å; R62-A66 VanDerWaalsContact O-N 3.08Å
63	K	84.4	Confident	80.2	Confident	15 Å²	15	74.9 Å²	74.9	7%	0.065	36%	0.358	C	S	.	.	H	α-helix	trans	-67	-43.6	171.9	-77.5	-172.4	170.6	-175.9	0	111.2	I51 P52 S54 S60 W65 A66 F67 E285 Y289	I51-K63 HydrophobicContact CG2-CG 4.44Å; P52-K63 HydrophobicContact CG-CG 4.18Å; P52-K63 WeakPolarHBondContact O-CE 3.06Å; S54-K63 WeakPolarHBondContact OG-CE 3.37Å; S60-K63 PolarHBondContact O-N 3.22Å; S60-K63 PolarHBondContact OG-N 3.3Å; K63-W65 VanDerWaalsContact C-N 3.3Å; K63-W65 PolarHBondContact O-N 3.15Å; K63-A66 WeakPolarHBondContact O-CA 3.29Å; K63-A66 VanDerWaalsContact O-CB 3.29Å; K63-A66 WeakPolarHBondContact O-CB 3.42Å; K63-A66 PolarHBondContact O-N 3.23Å; K63-F67 VanDerWaalsContact O-CD2 3.29Å; K63-F67 WeakPolarHBondContact O-CD2 3.44Å; K63-F67 PolarHBondContact O-N 3.42Å; K63-E285 WeakPolarHBondContact CD-OE1 3.13Å; K63-E285 IonicContact NZ-OE1 2.75Å; K63-E285 PolarHBondContact NZ-OE1 3.29Å; K63-E285 IonicContact NZ-OE2 2.87Å; K63-E285 PolarHBondContact NZ-OE2 3.39Å; K63-Y289 HydrophobicContact CB-CE1 4.18Å; K63-Y289 HydrophobicContact CB-CE2 4.02Å; K63-Y289 HydrophobicContact CD-CE2 4.06Å
64	L	87.6	Confident	81.2	Confident	20 Å²	20	65.9 Å²	65.9	11%	0.105	32%	0.316	C	S	.	.	H	α-helix	trans	-56.5	-45.4	176.5	-179.6	64.4	0	0	0	111.3	F59 S60 F61 A66 F67 T68 Y289 I292	F59-L64 HydrophobicContact CE2-CD2 4.45Å; F59-L64 HydrophobicContact CZ-CD2 3.97Å; S60-L64 PolarHBondContact O-N 3.08Å; F61-L64 PolarHBondContact O-N 3.14Å; L64-A66 VanDerWaalsContact C-N 3.31Å; L64-A66 PolarHBondContact O-N 2.99Å; L64-F67 CarbonylContact O-C 3.53Å; L64-F67 PolarHBondContact O-N 3.32Å; L64-F67 VanDerWaalsContact O-N 3.14Å; L64-T68 PolarHBondContact O-N 3.12Å; L64-T68 PolarHBondContact O-OG1 3.37Å; L64-Y289 HydrophobicContact CB-CD1 4.06Å; L64-Y289 HydrophobicContact CB-CE1 4.15Å; L64-Y289 HydrophobicContact CD1-CD1 4Å; L64-I292 HydrophobicContact CD1-CB 4.46Å; L64-I292 HydrophobicContact CD1-CG2 4.01Å
65	W	87.2	Confident	82.6	Confident	186 Å²	186	64.3 Å²	64.3	71%	0.705	31%	0.305	S	S	*	.	H	α-helix	trans	-61.9	-37.1	174.6	-172.9	-98.8	0	0	0	112.7	F61 K63 F67 T68 R199	F61-W65 WeakPolarHBondContact O-CB 3.07Å; F61-W65 PolarHBondContact O-N 2.88Å; K63-W65 VanDerWaalsContact C-N 3.3Å; K63-W65 PolarHBondContact O-N 3.15Å; W65-F67 VanDerWaalsContact C-N 3.31Å; W65-F67 PolarHBondContact O-N 3.28Å; W65-T68 PolarHBondContact O-N 3.49Å; W65-R199 PolarHBondContact O-NH2 3.3Å
66	A	85.4	Confident	84.4	Confident	8 Å²	8	58.5 Å²	58.5	7%	0.066	27%	0.267	C	S	.	.	H	α-helix	trans	-61.4	-39.8	173.5	0	0	0	0	0	112	P52 R62 K63 L64 R199 R273	P52-A66 HydrophobicContact CG-CB 4.26Å; R62-A66 PolarHBondContact O-N 3.31Å; R62-A66 VanDerWaalsContact O-N 3.08Å; K63-A66 WeakPolarHBondContact O-CA 3.29Å; K63-A66 VanDerWaalsContact O-CB 3.29Å; K63-A66 WeakPolarHBondContact O-CB 3.42Å; K63-A66 PolarHBondContact O-N 3.23Å; L64-A66 VanDerWaalsContact C-N 3.31Å; L64-A66 PolarHBondContact O-N 2.99Å; A66-R199 VanDerWaalsContact CA-NH2 3.26Å; A66-R199 PolarHBondContact O-NH2 2.86Å; A66-R273 PolarHBondContact O-NE 3.21Å
67	F	86.3	Confident	86	Confident	3 Å²	3	50.4 Å²	50.4	1%	0.013	22%	0.224	C	C	.	.	H	α-helix	trans	-81.3	-20.4	177	-78.7	-76.4	0	0	0	114.4	I51 K63 L64 W65 G69 P70 R273 V275 A286 Y289 F290	I51-F67 HydrophobicContact CD1-CE1 3.73Å; I51-F67 HydrophobicContact CD1-CE2 3.82Å; I51-F67 HydrophobicContact CD1-CZ 3.2Å; I51-F67 HydrophobicContact CG1-CE2 4.33Å; I51-F67 HydrophobicContact CG1-CZ 4.09Å; I51-F67 HydrophobicContact CG2-CE2 4.05Å; I51-F67 HydrophobicContact CG2-CZ 4.47Å; K63-F67 VanDerWaalsContact O-CD2 3.29Å; K63-F67 WeakPolarHBondContact O-CD2 3.44Å; K63-F67 PolarHBondContact O-N 3.42Å; L64-F67 CarbonylContact O-C 3.53Å; L64-F67 PolarHBondContact O-N 3.32Å; L64-F67 VanDerWaalsContact O-N 3.14Å; W65-F67 VanDerWaalsContact C-N 3.31Å; W65-F67 PolarHBondContact O-N 3.28Å; F67-G69 PolarHBondContact O-N 3.18Å; F67-P70 WeakPolarHBondContact O-CD 3.47Å; F67-R273 HydrophobicContact CD1-CB 4.31Å; F67-R273 HydrophobicContact CD1-CG 4.1Å; F67-R273 HydrophobicContact CE1-CB 4.26Å; F67-V275 HydrophobicContact CE1-CG2 4.4Å; F67-A286 HydrophobicContact CE1-CB 3.88Å; F67-A286 HydrophobicContact CZ-CB 3.87Å; F67-Y289 AromaticContact CD2-CD2 3.79Å; F67-Y289 HydrophobicContact CD2-CD2 3.79Å; F67-Y289 AromaticContact CD2-CG 3.76Å; F67-Y289 HydrophobicContact CD2-CG 3.76Å; F67-Y289 AromaticContact CE2-CD2 3.68Å; F67-Y289 HydrophobicContact CE2-CD2 3.68Å; F67-Y289 HydrophobicContact CE2-CE2 4.43Å; F67-Y289 HydrophobicContact CE2-CG 4.13Å; F67-Y289 HydrophobicContact CG-CG 4.4Å; F67-F290 HydrophobicContact CD1-CD1 4.34Å; F67-F290 HydrophobicContact CD1-CD2 4.25Å; F67-F290 AromaticContact CD1-CE1 3.89Å; F67-F290 HydrophobicContact CD1-CE1 3.89Å; F67-F290 AromaticContact CD1-CE2 3.8Å; F67-F290 HydrophobicContact CD1-CE2 3.8Å; F67-F290 AromaticContact CD1-CZ 3.62Å; F67-F290 HydrophobicContact CD1-CZ 3.62Å; F67-F290 HydrophobicContact CE1-CD2 4.32Å; F67-F290 AromaticContact CE1-CE2 3.76Å; F67-F290 HydrophobicContact CE1-CE2 3.76Å; F67-F290 AromaticContact CE1-CZ 3.95Å; F67-F290 HydrophobicContact CE1-CZ 3.95Å
68	T	89.4	Confident	87.4	Confident	26 Å²	26	44.5 Å²	44.5	16%	0.16	20%	0.196	C	C	.	.			trans	-63.9	131.8	178.9	-56.5	0	0	0	0	110.4	L64 W65 F72 R199 R273	L64-T68 PolarHBondContact O-N 3.12Å; L64-T68 PolarHBondContact O-OG1 3.37Å; W65-T68 PolarHBondContact O-N 3.49Å; T68-F72 HydrophobicContact CG2-CD2 3.75Å; T68-F72 HydrophobicContact CG2-CE2 3.7Å; T68-R199 PolarHBondContact O-NH1 3.31Å; T68-R273 PolarHBondContact O-NH2 2.73Å
69	G	89.3	Confident	88.8	Confident	3 Å²	3	36.2 Å²	36.2	3%	0.031	16%	0.155	C	C	.	.	S	Bend	trans	148.2	-73.5	-177.9	0	0	0	0	0	110.8	F67 G71 F72 L73 E202 E293	F67-G69 PolarHBondContact O-N 3.18Å; G69-G71 VanDerWaalsContact C-N 3.33Å; G69-G71 PolarHBondContact O-N 2.89Å; G69-F72 PolarHBondContact O-N 3.21Å; G69-L73 VanDerWaalsContact O-CD1 3.3Å; G69-L73 WeakPolarHBondContact O-CD1 3.39Å; G69-L73 PolarHBondContact O-N 3.49Å; G69-E202 VanDerWaalsContact CA-CD 3.44Å; G69-E293 PolarHBondContact N-OE1 3.22Å
70	P	90.8	Very high	89.3	Confident	1 Å²	1	32.9 Å²	32.9	1%	0.006	14%	0.141	C	C	.	.	H	α-helix	trans	-50.4	-43	-176.4	-34.1	42	0	0	0	115.6	F67 L73 M74 L269 V270 F290	F67-P70 WeakPolarHBondContact O-CD 3.47Å; P70-L73 PolarHBondContact O-N 3.31Å; P70-M74 WeakPolarHBondContact O-CB 3.13Å; P70-M74 PolarHBondContact O-N 3.45Å; P70-L269 HydrophobicContact CB-CB 3.85Å; P70-L269 HydrophobicContact CG-CB 4.46Å; P70-L269 WeakPolarHBondContact CG-O 3.26Å; P70-V270 HydrophobicContact CB-CG1 4.47Å; P70-F290 HydrophobicContact CB-CE1 4.21Å; P70-F290 HydrophobicContact CG-CE1 3.99Å
71	G	92.3	Very high	89.5	Confident	0 Å²	0	32.1 Å²	32.1	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-67	-38.3	178.1	0	0	0	0	0	113	G69 M74 S75 E293 A297	G69-G71 VanDerWaalsContact C-N 3.33Å; G69-G71 PolarHBondContact O-N 2.89Å; G71-M74 PolarHBondContact O-N 3.4Å; G71-S75 WeakPolarHBondContact O-CB 2.88Å; G71-S75 PolarHBondContact O-N 2.91Å; G71-E293 WeakPolarHBondContact CA-OE1 2.92Å; G71-E293 PolarHBondContact N-OE1 3.11Å; G71-E293 PolarHBondContact N-OE2 2.91Å; G71-A297 WeakPolarHBondContact O-CB 3.46Å
72	F	91.8	Very high	89.7	Confident	50 Å²	50	24.5 Å²	24.5	22%	0.219	10%	0.102	C	C	.	.	H	α-helix	trans	-70.1	-37.1	174.1	-79.7	-83.3	0	0	0	112.5	T68 G69 M74 S75 I76 I209 I296 A297	T68-F72 HydrophobicContact CG2-CD2 3.75Å; T68-F72 HydrophobicContact CG2-CE2 3.7Å; G69-F72 PolarHBondContact O-N 3.21Å; F72-M74 VanDerWaalsContact C-N 3.33Å; F72-S75 PolarHBondContact O-N 2.99Å; F72-S75 PolarHBondContact O-OG 2.9Å; F72-S75 VanDerWaalsContact O-OG 3.07Å; F72-I76 PolarHBondContact O-N 3.45Å; F72-I209 HydrophobicContact CB-CD1 4.35Å; F72-I209 HydrophobicContact CD1-CD1 4.01Å; F72-I296 HydrophobicContact CZ-CG2 4.26Å; F72-A297 HydrophobicContact CD1-CB 4.03Å; F72-A297 HydrophobicContact CD2-CB 4.26Å; F72-A297 HydrophobicContact CE1-CB 4.25Å; F72-A297 HydrophobicContact CE2-CB 4.46Å; F72-A297 HydrophobicContact CG-CB 4.04Å; F72-A297 HydrophobicContact CZ-CB 4.47Å
73	L	90.6	Very high	90	Very high	4 Å²	4	15.3 Å²	15.3	2%	0.021	7%	0.067	C	C	.	.	H	α-helix	trans	-64.6	-40.8	173.5	-91.1	65.8	0	0	0	111.3	G69 P70 E202 F205 L269	G69-L73 VanDerWaalsContact O-CD1 3.3Å; G69-L73 WeakPolarHBondContact O-CD1 3.39Å; G69-L73 PolarHBondContact O-N 3.49Å; P70-L73 PolarHBondContact O-N 3.31Å; L73-E202 HydrophobicContact CD1-CB 4.26Å; L73-E202 HydrophobicContact CD1-CG 3.76Å; L73-F205 HydrophobicContact CD1-CB 4.19Å; L73-F205 HydrophobicContact CD1-CD2 3.57Å; L73-F205 HydrophobicContact CD1-CE2 4.25Å; L73-F205 HydrophobicContact CD1-CG 4.2Å; L73-F205 HydrophobicContact CD2-CD2 4.11Å; L73-F205 HydrophobicContact CD2-CE2 3.96Å; L73-F205 HydrophobicContact CG-CD2 3.58Å; L73-F205 HydrophobicContact CG-CE2 3.77Å; L73-F205 HydrophobicContact CG-CG 4.31Å; L73-L269 HydrophobicContact CB-CD1 3.65Å; L73-L269 HydrophobicContact CD2-CD1 4.37Å; L73-L269 HydrophobicContact CD2-CD2 3.96Å
74	M	92.6	Very high	90.4	Very high	0 Å²	0	14.7 Å²	14.7	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-65.2	-37.6	175.1	173	-80.9	-68.1	0	0	112.3	P70 G71 F72 I76 A77 Y78 Q113 N262 H266 L298	P70-M74 WeakPolarHBondContact O-CB 3.13Å; P70-M74 PolarHBondContact O-N 3.45Å; G71-M74 PolarHBondContact O-N 3.4Å; F72-M74 VanDerWaalsContact C-N 3.33Å; M74-I76 PolarHBondContact O-N 3.42Å; M74-A77 PolarHBondContact O-N 2.92Å; M74-Y78 HydrophobicContact SD-CD2 4.19Å; M74-Y78 HydrophobicContact SD-CE2 3.66Å; M74-Q113 HydrophobicContact CE-CB 4.09Å; M74-Q113 HydrophobicContact CE-CG 4.01Å; M74-Q113 HydrophobicContact CG-CG 4.36Å; M74-Q113 HydrophobicContact SD-CB 4.4Å; M74-Q113 HydrophobicContact SD-CG 3.68Å; M74-N262 WeakPolarHBondContact CG-OD1 3.48Å; M74-N262 PolarHBondContact O-ND2 3.34Å; M74-N262 PolarHBondContact O-OD1 3.29Å; M74-H266 HydrophobicContact CB-CB 4.12Å; M74-H266 HydrophobicContact CG-CB 3.7Å; M74-L298 HydrophobicContact CE-CD1 3.95Å; M74-L298 HydrophobicContact CE-CD2 4.17Å; M74-L298 HydrophobicContact CE-CG 3.9Å; M74-L298 HydrophobicContact SD-CD1 4.35Å; M74-L298 HydrophobicContact SD-CD2 3.89Å; M74-L298 HydrophobicContact SD-CG 4.27Å
75	S	93.2	Very high	90.6	Very high	0 Å²	0	13.8 Å²	13.8	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-72.4	-11.9	-176	80.1	0	0	0	0	113.8	G71 F72 A77 Y78 S301	G71-S75 WeakPolarHBondContact O-CB 2.88Å; G71-S75 PolarHBondContact O-N 2.91Å; F72-S75 PolarHBondContact O-N 2.99Å; F72-S75 PolarHBondContact O-OG 2.9Å; F72-S75 VanDerWaalsContact O-OG 3.07Å; S75-A77 VanDerWaalsContact C-N 3.34Å; S75-Y78 WeakPolarHBondContact O-CB 3.45Å; S75-Y78 PolarHBondContact O-N 2.79Å; S75-Y78 VanDerWaalsContact O-N 3.16Å; S75-S301 VanDerWaalsContact CB-OG 3.3Å; S75-S301 WeakPolarHBondContact CB-OG 3.38Å; S75-S301 PolarHBondContact O-OG 3.49Å; S75-S301 PolarHBondContact OG-OG 3.33Å
76	I	91.1	Very high	90.8	Very high	0 Å²	0	5.1 Å²	5.1	0%	0	3%	0.028	C	C	.	.	G	3₁₀ helix	trans	-66.1	-37.2	174.6	-73.3	166.1	0	0	0	111.9	F72 M74 Y78 L79 D80 F205 I209 S379 T383	F72-I76 PolarHBondContact O-N 3.45Å; M74-I76 PolarHBondContact O-N 3.42Å; I76-Y78 PolarHBondContact O-N 3.01Å; I76-Y78 VanDerWaalsContact O-N 3.09Å; I76-L79 CarbonylContact O-C 3.6Å; I76-L79 WeakPolarHBondContact O-CA 3.5Å; I76-L79 PolarHBondContact O-N 2.81Å; I76-D80 PolarHBondContact O-N 3.14Å; I76-F205 HydrophobicContact CD1-CB 3.78Å; I76-F205 HydrophobicContact CD1-CD1 3.13Å; I76-F205 HydrophobicContact CD1-CD2 4.49Å; I76-F205 HydrophobicContact CD1-CE1 3.71Å; I76-F205 HydrophobicContact CD1-CG 3.57Å; I76-I209 HydrophobicContact CD1-CD1 4.38Å; I76-I209 HydrophobicContact CG1-CD1 3.86Å; I76-I209 HydrophobicContact CG1-CG1 4Å; I76-S379 VanDerWaalsContact CG2-OG 3.23Å; I76-S379 WeakPolarHBondContact CG2-OG 3.41Å; I76-T383 HydrophobicContact CB-CG2 4.01Å; I76-T383 HydrophobicContact CD1-CG2 4.39Å; I76-T383 HydrophobicContact CG2-CG2 3.82Å
77	A	89.1	Confident	91.1	Very high	0 Å²	0	4.7 Å²	4.7	0%	0	2%	0.024	C	C	.	.	G	3₁₀ helix	trans	-66	-10.9	175.6	0	0	0	0	0	112.3	M74 S75 L79 M259 N262	M74-A77 PolarHBondContact O-N 2.92Å; S75-A77 VanDerWaalsContact C-N 3.34Å; A77-L79 VanDerWaalsContact C-N 3.31Å; A77-M259 HydrophobicContact CB-SD 3.81Å; A77-N262 HydrophobicContact CB-CB 4Å; A77-N262 WeakPolarHBondContact CB-ND2 3.01Å
78	Y	92.2	Very high	91.4	Very high	4 Å²	4	4.6 Å²	4.6	2%	0.016	2%	0.024	C	C	.	.	G	3₁₀ helix	trans	-87.8	-2.8	169.6	-70.9	-109.1	0	0	0	112.8	M74 S75 I76 N83 G109 V257 N262 L298 N305	M74-Y78 HydrophobicContact SD-CD2 4.19Å; M74-Y78 HydrophobicContact SD-CE2 3.66Å; S75-Y78 WeakPolarHBondContact O-CB 3.45Å; S75-Y78 PolarHBondContact O-N 2.79Å; S75-Y78 VanDerWaalsContact O-N 3.16Å; I76-Y78 PolarHBondContact O-N 3.01Å; I76-Y78 VanDerWaalsContact O-N 3.09Å; Y78-N83 VanDerWaalsContact O-CG 3.29Å; Y78-N83 PolarHBondContact O-ND2 3.34Å; Y78-G109 WeakPolarHBondContact OH-CA 3.4Å; Y78-V257 HydrophobicContact CD1-CG1 3.81Å; Y78-V257 WeakPolarHBondContact CD1-O 3.19Å; Y78-V257 HydrophobicContact CE1-CG1 3.54Å; Y78-V257 WeakPolarHBondContact CE1-O 3.39Å; Y78-N262 VanDerWaalsContact CE2-ND2 3.3Å; Y78-N262 WeakPolarHBondContact CE2-ND2 3.1Å; Y78-L298 HydrophobicContact CD1-CD2 3.83Å; Y78-L298 HydrophobicContact CD2-CD2 3.41Å; Y78-L298 VanDerWaalsContact CD2-CD2 3.41Å; Y78-L298 HydrophobicContact CE1-CD2 3.87Å; Y78-L298 HydrophobicContact CE2-CD2 3.46Å; Y78-L298 VanDerWaalsContact CE2-CD2 3.46Å; Y78-L298 HydrophobicContact CG-CD2 3.62Å; Y78-N305 PolarHBondContact O-ND2 3.46Å; Y78-N305 VanDerWaalsContact O-ND2 3.14Å; Y78-N305 PolarHBondContact O-OD1 2.68Å
79	L	93.7	Very high	91.5	Very high	1 Å²	1	3.8 Å²	3.8	1%	0.005	2%	0.018	C	C	.	.	S	Bend	trans	-128.1	14	-174.2	-61.2	176.2	0	0	0	111.7	I76 A77 I84 I209 M212 S301 I304 N305 A376	I76-L79 CarbonylContact O-C 3.6Å; I76-L79 WeakPolarHBondContact O-CA 3.5Å; I76-L79 PolarHBondContact O-N 2.81Å; A77-L79 VanDerWaalsContact C-N 3.31Å; L79-I84 WeakPolarHBondContact O-CD1 3.38Å; L79-I209 HydrophobicContact CD1-CG2 4.38Å; L79-M212 HydrophobicContact CB-CE 4Å; L79-M212 HydrophobicContact CB-SD 3.99Å; L79-M212 HydrophobicContact CD1-CE 3.83Å; L79-M212 HydrophobicContact CD1-SD 4.49Å; L79-S301 WeakPolarHBondContact CD1-OG 3.29Å; L79-I304 HydrophobicContact CD1-CD1 3.66Å; L79-I304 HydrophobicContact CD2-CB 3.69Å; L79-I304 HydrophobicContact CD2-CD1 3.98Å; L79-I304 HydrophobicContact CD2-CG1 4.44Å; L79-I304 HydrophobicContact CD2-CG2 3.66Å; L79-I304 HydrophobicContact CG-CD1 4.49Å; L79-N305 WeakPolarHBondContact CD2-OD1 3.28Å; L79-A376 VanDerWaalsContact O-CB 3.22Å; L79-A376 WeakPolarHBondContact O-CB 3.39Å
80	D	91.9	Very high	91.6	Very high	0 Å²	0	3.7 Å²	3.7	0%	0	2%	0.017	C	C	.	.	S	Bend	trans	-70.8	163.2	178	74.3	-25.7	0	0	0	110.8	I76 G82 N83 I84 M259 S380	I76-D80 PolarHBondContact O-N 3.14Å; D80-G82 PolarHBondContact O-N 2.67Å; D80-N83 PolarHBondContact O-N 2.96Å; D80-N83 VanDerWaalsContact O-N 3.14Å; D80-N83 WeakPolarHBondContact OD1-CB 3.36Å; D80-N83 PolarHBondContact OD1-N 3.07Å; D80-I84 WeakPolarHBondContact O-CG1 3.37Å; D80-I84 PolarHBondContact O-N 3.01Å; D80-M259 WeakPolarHBondContact OD2-CE 3.46Å; D80-S380 WeakPolarHBondContact CB-OG 3.35Å
81	P	90.8	Very high	91.7	Very high	0 Å²	0	3.6 Å²	3.6	0%	0	2%	0.017	C	C	.	.	H	α-helix	trans	-58.3	-28.6	178.1	-27.7	37.7	0	0	0	113.9	E85 I350 A376	P81-E85 VanDerWaalsContact O-CB 3.32Å; P81-E85 WeakPolarHBondContact O-CB 3.4Å; P81-E85 PolarHBondContact O-N 2.92Å; P81-I350 HydrophobicContact CB-CD1 4.1Å; P81-A376 HydrophobicContact CG-CB 4.3Å
82	G	88.9	Confident	91.6	Very high	0 Å²	0	4.2 Å²	4.2	0%	0	2%	0.021	C	C	.	.	H	α-helix	trans	-63.4	-45	174.9	0	0	0	0	0	112.5	D80 S86 N437	D80-G82 PolarHBondContact O-N 2.67Å; G82-S86 PolarHBondContact O-N 3.12Å; G82-S86 VanDerWaalsContact O-N 3.09Å; G82-N437 PolarHBondContact O-ND2 2.78Å; G82-N437 VanDerWaalsContact O-ND2 3.09Å
83	N	91.8	Very high	91.4	Very high	0 Å²	0	5 Å²	5	0%	0	3%	0.025	C	C	.	.	H	α-helix	trans	-69.1	-44.9	175.7	-163.8	-29.2	0	0	0	112.4	Y78 D80 E85 S86 D87 A256 N305	Y78-N83 VanDerWaalsContact O-CG 3.29Å; Y78-N83 PolarHBondContact O-ND2 3.34Å; D80-N83 PolarHBondContact O-N 2.96Å; D80-N83 VanDerWaalsContact O-N 3.14Å; D80-N83 WeakPolarHBondContact OD1-CB 3.36Å; D80-N83 PolarHBondContact OD1-N 3.07Å; N83-E85 VanDerWaalsContact C-N 3.26Å; N83-E85 PolarHBondContact O-N 3.35Å; N83-S86 PolarHBondContact O-N 3.06Å; N83-S86 VanDerWaalsContact O-N 3.09Å; N83-D87 WeakPolarHBondContact O-CB 3.18Å; N83-D87 PolarHBondContact O-N 2.79Å; N83-D87 PolarHBondContact OD1-OD2 2.6Å; N83-A256 HydrophobicContact CB-CB 4.4Å; N83-A256 PolarHBondContact ND2-O 3.46Å; N83-N305 PolarHBondContact OD1-ND2 2.98Å
84	I	93.4	Very high	91.4	Very high	3 Å²	3	4.8 Å²	4.8	2%	0.015	2%	0.024	C	C	.	.	H	α-helix	trans	-58.7	-39.4	176.4	-64.8	168.5	0	0	0	111.2	L79 D80 D87 L88 F216 V308 W369 I373 A376	L79-I84 WeakPolarHBondContact O-CD1 3.38Å; D80-I84 WeakPolarHBondContact O-CG1 3.37Å; D80-I84 PolarHBondContact O-N 3.01Å; I84-D87 PolarHBondContact O-N 2.76Å; I84-L88 HydrophobicContact CG2-CD2 4.4Å; I84-L88 WeakPolarHBondContact O-CB 3.39Å; I84-L88 WeakPolarHBondContact O-CD2 3.32Å; I84-L88 WeakPolarHBondContact O-CG 3.41Å; I84-L88 PolarHBondContact O-N 3.14Å; I84-F216 HydrophobicContact CD1-CE2 3.85Å; I84-F216 HydrophobicContact CD1-CZ 3.79Å; I84-V308 HydrophobicContact CG2-CG1 4.15Å; I84-V308 HydrophobicContact CG2-CG2 4.44Å; I84-W369 HydrophobicContact CG2-CH2 3.71Å; I84-W369 HydrophobicContact CG2-CZ2 4.28Å; I84-I373 HydrophobicContact CB-CD1 4.46Å; I84-I373 HydrophobicContact CD1-CD1 4.12Å; I84-I373 HydrophobicContact CG2-CD1 3.67Å; I84-A376 HydrophobicContact CD1-CB 3.58Å
85	E	91.4	Very high	91.3	Very high	1 Å²	1	4.9 Å²	4.9	1%	0.005	3%	0.025	C	C	.	.	H	α-helix	trans	-63.1	-47.5	173.1	-178.6	76.4	-145.7	0	0	112.4	P81 N83 D87 L88 Q89 D349 I350 N433	P81-E85 VanDerWaalsContact O-CB 3.32Å; P81-E85 WeakPolarHBondContact O-CB 3.4Å; P81-E85 PolarHBondContact O-N 2.92Å; N83-E85 VanDerWaalsContact C-N 3.26Å; N83-E85 PolarHBondContact O-N 3.35Å; E85-D87 VanDerWaalsContact C-N 3.25Å; E85-D87 PolarHBondContact O-N 2.83Å; E85-L88 WeakPolarHBondContact O-CG 3.48Å; E85-L88 PolarHBondContact O-N 3.12Å; E85-Q89 HydrophobicContact CG-CG 4.48Å; E85-Q89 WeakPolarHBondContact O-CB 3.42Å; E85-Q89 VanDerWaalsContact O-CG 3.28Å; E85-Q89 WeakPolarHBondContact O-CG 3.19Å; E85-Q89 PolarHBondContact O-N 2.95Å; E85-Q89 PolarHBondContact OE1-NE2 3.37Å; E85-D349 WeakPolarHBondContact OE1-CA 3.33Å; E85-I350 HydrophobicContact CB-CD1 4.09Å; E85-I350 HydrophobicContact CB-CG1 4.34Å; E85-I350 WeakPolarHBondContact OE2-CD1 3.17Å; E85-I350 WeakPolarHBondContact OE2-CG1 3.5Å; E85-I350 PolarHBondContact OE2-N 3.32Å; E85-N433 WeakPolarHBondContact CB-ND2 3.37Å; E85-N433 HydrophobicContact CG-CB 4.36Å; E85-N433 WeakPolarHBondContact CG-ND2 3.23Å
86	S	90.2	Very high	91.2	Very high	3 Å²	3	5.6 Å²	5.6	2%	0.021	3%	0.028	C	C	.	.	H	α-helix	trans	-60.9	-39.7	177.8	-173.6	0	0	0	0	111.4	G82 N83 S90 G252 I253	G82-S86 PolarHBondContact O-N 3.12Å; G82-S86 VanDerWaalsContact O-N 3.09Å; N83-S86 PolarHBondContact O-N 3.06Å; N83-S86 VanDerWaalsContact O-N 3.09Å; S86-S90 WeakPolarHBondContact O-CB 3.19Å; S86-S90 PolarHBondContact O-N 3.32Å; S86-G252 PolarHBondContact OG-O 2.97Å; S86-I253 PolarHBondContact OG-N 2.74Å
87	D	93.4	Very high	91.2	Very high	0 Å²	0	7.2 Å²	7.2	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-67.5	-48.4	179.7	-80.9	-14.3	0	0	0	112.1	N83 I84 E85 Q89 S90 G91 N305 V308 V309	N83-D87 WeakPolarHBondContact O-CB 3.18Å; N83-D87 PolarHBondContact O-N 2.79Å; N83-D87 PolarHBondContact OD1-OD2 2.6Å; I84-D87 PolarHBondContact O-N 2.76Å; E85-D87 VanDerWaalsContact C-N 3.25Å; E85-D87 PolarHBondContact O-N 2.83Å; D87-Q89 VanDerWaalsContact C-N 3.3Å; D87-Q89 PolarHBondContact O-N 3.48Å; D87-S90 PolarHBondContact O-N 3Å; D87-S90 PolarHBondContact O-OG 3.03Å; D87-G91 PolarHBondContact O-N 3.12Å; D87-N305 WeakPolarHBondContact OD2-CA 3.27Å; D87-N305 WeakPolarHBondContact OD2-CB 3.37Å; D87-N305 VanDerWaalsContact OD2-CG 3.23Å; D87-N305 PolarHBondContact OD2-ND2 3.42Å; D87-V308 HydrophobicContact CB-CB 4.4Å; D87-V308 HydrophobicContact CB-CG1 4.01Å; D87-V309 HydrophobicContact CB-CG2 3.6Å
88	L	92.6	Very high	91.3	Very high	0 Å²	0	7.4 Å²	7.4	0%	0	4%	0.036	C	C	.	.	H	α-helix	trans	-63.1	-39.3	179.2	76.1	90	0	0	0	111.2	I84 E85 G91 A92 V308 F312 V348 I350 W369	I84-L88 HydrophobicContact CG2-CD2 4.4Å; I84-L88 WeakPolarHBondContact O-CB 3.39Å; I84-L88 WeakPolarHBondContact O-CD2 3.32Å; I84-L88 WeakPolarHBondContact O-CG 3.41Å; I84-L88 PolarHBondContact O-N 3.14Å; E85-L88 WeakPolarHBondContact O-CG 3.48Å; E85-L88 PolarHBondContact O-N 3.12Å; L88-G91 PolarHBondContact O-N 2.88Å; L88-A92 WeakPolarHBondContact O-CB 3.43Å; L88-A92 PolarHBondContact O-N 2.71Å; L88-V308 HydrophobicContact CB-CG1 3.92Å; L88-F312 HydrophobicContact CB-CB 4.31Å; L88-F312 HydrophobicContact CB-CD1 4.03Å; L88-F312 HydrophobicContact CB-CD2 3.7Å; L88-F312 HydrophobicContact CB-CE1 4.31Å; L88-F312 HydrophobicContact CB-CE2 4.02Å; L88-F312 HydrophobicContact CB-CG 3.73Å; L88-F312 HydrophobicContact CB-CZ 4.32Å; L88-V348 HydrophobicContact CD1-CB 4.01Å; L88-V348 HydrophobicContact CD1-CG1 3.41Å; L88-V348 VanDerWaalsContact CD1-CG1 3.41Å; L88-I350 HydrophobicContact CD2-CB 4.46Å; L88-I350 HydrophobicContact CD2-CG1 3.73Å; L88-W369 HydrophobicContact CD2-CH2 4.26Å; L88-W369 HydrophobicContact CD2-CZ2 4.07Å
89	Q	90.8	Very high	91.4	Very high	10 Å²	10	7.2 Å²	7.2	5%	0.047	4%	0.035	C	C	.	.	H	α-helix	trans	-67.3	-39.9	176.5	-73.1	-166.4	10.8	0	0	112.3	E85 D87 G91 A92 K93 Q249 D434	E85-Q89 HydrophobicContact CG-CG 4.48Å; E85-Q89 WeakPolarHBondContact O-CB 3.42Å; E85-Q89 VanDerWaalsContact O-CG 3.28Å; E85-Q89 WeakPolarHBondContact O-CG 3.19Å; E85-Q89 PolarHBondContact O-N 2.95Å; E85-Q89 PolarHBondContact OE1-NE2 3.37Å; D87-Q89 VanDerWaalsContact C-N 3.3Å; D87-Q89 PolarHBondContact O-N 3.48Å; Q89-G91 VanDerWaalsContact C-N 3.33Å; Q89-G91 PolarHBondContact O-N 2.98Å; Q89-A92 PolarHBondContact O-N 2.86Å; Q89-K93 WeakPolarHBondContact O-CB 3.04Å; Q89-K93 WeakPolarHBondContact O-CG 3.31Å; Q89-K93 PolarHBondContact O-N 3.26Å; Q89-Q249 VanDerWaalsContact OE1-NE2 3.15Å; Q89-D434 VanDerWaalsContact NE2-CG 3.29Å; Q89-D434 PolarHBondContact NE2-OD1 2.94Å; Q89-D434 PolarHBondContact NE2-OD2 3.35Å; Q89-D434 VanDerWaalsContact NE2-OD2 3.17Å; Q89-D434 PolarHBondContact OE1-OD1 2.85Å
90	S	91.1	Very high	91.3	Very high	0 Å²	0	10.9 Å²	10.9	0%	0	5%	0.049	C	C	.	.	H	α-helix	trans	-62.7	-41.8	177.1	77.4	0	0	0	0	111.7	S86 D87 A94	S86-S90 WeakPolarHBondContact O-CB 3.19Å; S86-S90 PolarHBondContact O-N 3.32Å; D87-S90 PolarHBondContact O-N 3Å; D87-S90 PolarHBondContact O-OG 3.03Å; S90-A94 WeakPolarHBondContact O-CA 3.27Å; S90-A94 VanDerWaalsContact O-CB 3.29Å; S90-A94 WeakPolarHBondContact O-CB 3.48Å; S90-A94 PolarHBondContact O-N 2.67Å
91	G	91.9	Very high	91.4	Very high	0 Å²	0	11.4 Å²	11.4	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-62.6	-48.5	173.8	0	0	0	0	0	111.5	D87 L88 Q89 K93 G95 A313	D87-G91 PolarHBondContact O-N 3.12Å; L88-G91 PolarHBondContact O-N 2.88Å; Q89-G91 VanDerWaalsContact C-N 3.33Å; Q89-G91 PolarHBondContact O-N 2.98Å; G91-K93 PolarHBondContact O-N 3.02Å; G91-G95 WeakPolarHBondContact O-CA 3.08Å; G91-G95 PolarHBondContact O-N 3.09Å; G91-A313 VanDerWaalsContact O-CA 3.29Å; G91-A313 WeakPolarHBondContact O-CA 3.44Å
92	A	90.6	Very high	91.5	Very high	12 Å²	12	11.4 Å²	11.4	10%	0.099	5%	0.052	C	C	.	.	H	α-helix	trans	-63.5	-41.8	-179.1	0	0	0	0	0	113.7	L88 Q89 F316 V348	L88-A92 WeakPolarHBondContact O-CB 3.43Å; L88-A92 PolarHBondContact O-N 2.71Å; Q89-A92 PolarHBondContact O-N 2.86Å; A92-F316 HydrophobicContact CB-CB 3.9Å; A92-V348 HydrophobicContact CB-CB 3.95Å; A92-V348 HydrophobicContact CB-CG2 3.45Å; A92-V348 VanDerWaalsContact CB-CG2 3.45Å
93	K	88.8	Confident	91.9	Very high	66 Å²	66	13.3 Å²	13.3	29%	0.287	6%	0.062	S	C	.	.	H	α-helix	trans	-89.8	-31.2	-174.1	-68.2	171	-179.3	167.1	0	113.5	Q89 G91 V245 Q249	Q89-K93 WeakPolarHBondContact O-CB 3.04Å; Q89-K93 WeakPolarHBondContact O-CG 3.31Å; Q89-K93 PolarHBondContact O-N 3.26Å; G91-K93 PolarHBondContact O-N 3.02Å; K93-V245 HydrophobicContact CB-CG1 4.49Å; K93-V245 HydrophobicContact CD-CG1 4.04Å; K93-Q249 HydrophobicContact CB-CG 4.32Å; K93-Q249 HydrophobicContact CD-CG 3.82Å; K93-Q249 VanDerWaalsContact NZ-NE2 3.15Å
94	A	89.6	Confident	91.9	Very high	1 Å²	1	16.4 Å²	16.4	1%	0.008	8%	0.081	C	C	.	.	H	α-helix	trans	-119	-3.2	-174.1	0	0	0	0	0	114.4	S90 K97 L98 Q246	S90-A94 WeakPolarHBondContact O-CA 3.27Å; S90-A94 VanDerWaalsContact O-CB 3.29Å; S90-A94 WeakPolarHBondContact O-CB 3.48Å; S90-A94 PolarHBondContact O-N 2.67Å; A94-K97 WeakPolarHBondContact O-CB 3.35Å; A94-K97 WeakPolarHBondContact O-CG 3.48Å; A94-K97 PolarHBondContact O-N 3.28Å; A94-L98 HydrophobicContact CB-CB 4.43Å; A94-L98 HydrophobicContact CB-CD1 3.43Å; A94-L98 VanDerWaalsContact CB-CD1 3.43Å; A94-L98 HydrophobicContact CB-CG 3.55Å; A94-Q246 HydrophobicContact CB-CB 4.45Å; A94-Q246 HydrophobicContact CB-CG 3.91Å
95	G	90.8	Very high	91.9	Very high	2 Å²	2	16.4 Å²	16.4	2%	0.021	8%	0.081	C	C	.	.	G	3₁₀ helix	trans	61.5	-138.8	-176.3	0	0	0	0	0	110.7	G91 K97 Y317	G91-G95 WeakPolarHBondContact O-CA 3.08Å; G91-G95 PolarHBondContact O-N 3.09Å; G95-K97 VanDerWaalsContact C-N 3.26Å; G95-K97 PolarHBondContact O-N 3.23Å; G95-Y317 VanDerWaalsContact N-CD2 3.29Å
96	F	91.8	Very high	92.1	Very high	14 Å²	14	17 Å²	17	6%	0.061	9%	0.085	C	C	.	.	G	3₁₀ helix	trans	-79.1	-1.9	179	-55.6	-71.1	0	0	0	114.5	L98 L99 P225 E229 V230 G233 A310 A313 Q314	F96-L98 VanDerWaalsContact C-N 3.34Å; F96-L98 PolarHBondContact O-N 3.02Å; F96-L99 HydrophobicContact CB-CD1 4.13Å; F96-L99 HydrophobicContact CD1-CD1 3.93Å; F96-L99 PolarHBondContact O-N 3.02Å; F96-P225 HydrophobicContact CE1-CB 4.33Å; F96-P225 HydrophobicContact CZ-CB 4.3Å; F96-E229 HydrophobicContact CD2-CB 3.7Å; F96-E229 VanDerWaalsContact CD2-OE2 3.22Å; F96-E229 WeakPolarHBondContact CD2-OE2 3.2Å; F96-E229 HydrophobicContact CE2-CB 4.05Å; F96-E229 VanDerWaalsContact CE2-OE2 3.24Å; F96-E229 WeakPolarHBondContact CE2-OE2 3.24Å; F96-E229 HydrophobicContact CG-CB 4.14Å; F96-V230 HydrophobicContact CD1-CG2 3.74Å; F96-V230 HydrophobicContact CE1-CG2 3.51Å; F96-V230 HydrophobicContact CZ-CG2 4.39Å; F96-G233 VanDerWaalsContact O-CA 3.23Å; F96-G233 WeakPolarHBondContact O-CA 3.45Å; F96-A310 HydrophobicContact CE1-CB 4.09Å; F96-A313 HydrophobicContact CD1-CB 3.9Å; F96-A313 HydrophobicContact CE1-CB 3.68Å; F96-A313 HydrophobicContact CE2-CB 4.35Å; F96-A313 HydrophobicContact CG-CB 4.34Å; F96-A313 HydrophobicContact CZ-CB 3.92Å; F96-Q314 HydrophobicContact CZ-CB 4.44Å
97	K	90.2	Very high	92.3	Very high	35 Å²	35	20.3 Å²	20.3	15%	0.152	11%	0.105	C	C	.	.	G	3₁₀ helix	trans	-69.5	-26.2	-169.7	-61	178.6	-175.1	-178.6	0	114.2	A94 G95 W100 Y238 A240	A94-K97 WeakPolarHBondContact O-CB 3.35Å; A94-K97 WeakPolarHBondContact O-CG 3.48Å; A94-K97 PolarHBondContact O-N 3.28Å; G95-K97 VanDerWaalsContact C-N 3.26Å; G95-K97 PolarHBondContact O-N 3.23Å; K97-W100 PolarHBondContact O-NE1 3.3Å; K97-W100 VanDerWaalsContact O-NE1 3.12Å; K97-Y238 HydrophobicContact CG-CE2 3.92Å; K97-A240 PolarHBondContact NZ-O 2.99Å
98	L	91.6	Very high	92.3	Very high	3 Å²	3	22.4 Å²	22.4	2%	0.016	12%	0.116	C	C	.	.	G	3₁₀ helix	trans	-97.7	1.6	-176.2	-64.2	-179.5	0	0	0	113.9	A94 F96 W100 V101 L102 Q249 A250 I253	A94-L98 HydrophobicContact CB-CB 4.43Å; A94-L98 HydrophobicContact CB-CD1 3.43Å; A94-L98 VanDerWaalsContact CB-CD1 3.43Å; A94-L98 HydrophobicContact CB-CG 3.55Å; F96-L98 VanDerWaalsContact C-N 3.34Å; F96-L98 PolarHBondContact O-N 3.02Å; L98-W100 VanDerWaalsContact C-N 3.25Å; L98-W100 PolarHBondContact O-N 3.03Å; L98-V101 HydrophobicContact CD2-CG2 4.09Å; L98-V101 WeakPolarHBondContact O-CA 3.49Å; L98-V101 VanDerWaalsContact O-CB 3.32Å; L98-V101 WeakPolarHBondContact O-CB 3.49Å; L98-V101 PolarHBondContact O-N 3.32Å; L98-L102 PolarHBondContact O-N 3.47Å; L98-L102 VanDerWaalsContact O-N 3.16Å; L98-Q249 HydrophobicContact CD1-CB 3.74Å; L98-A250 HydrophobicContact CD1-CB 4.48Å; L98-A250 HydrophobicContact CD2-CB 3.89Å; L98-I253 HydrophobicContact CB-CD1 3.76Å; L98-I253 HydrophobicContact CD1-CD1 4.13Å
99	L	93.5	Very high	92.4	Very high	0 Å²	0	22.4 Å²	22.4	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-59.6	-33.8	179.3	-80.1	172.5	0	0	0	113.1	F96 V101 L102 L103 V230 M234 V306 V309	F96-L99 HydrophobicContact CB-CD1 4.13Å; F96-L99 HydrophobicContact CD1-CD1 3.93Å; F96-L99 PolarHBondContact O-N 3.02Å; L99-V101 VanDerWaalsContact C-N 3.29Å; L99-V101 PolarHBondContact O-N 2.9Å; L99-L102 HydrophobicContact CD2-CD2 4.35Å; L99-L102 WeakPolarHBondContact O-CB 3.03Å; L99-L102 PolarHBondContact O-N 3.06Å; L99-L103 PolarHBondContact O-N 3.29Å; L99-V230 HydrophobicContact CD1-CB 4.45Å; L99-V230 HydrophobicContact CD1-CG1 4.11Å; L99-M234 HydrophobicContact CB-CG 3.89Å; L99-M234 HydrophobicContact CD1-CG 4.16Å; L99-M234 HydrophobicContact CG-CG 4.46Å; L99-V306 HydrophobicContact CD2-CG2 4.34Å; L99-V309 HydrophobicContact CD2-CB 3.83Å; L99-V309 HydrophobicContact CD2-CG1 3.58Å; L99-V309 HydrophobicContact CD2-CG2 4.42Å; L99-V309 HydrophobicContact CG-CG1 4.02Å
100	W	93.3	Very high	92.6	Very high	78 Å²	78	23.4 Å²	23.4	30%	0.295	12%	0.121	S	C	.	.	H	α-helix	trans	-66.6	-31.7	174.4	72.6	-89.7	0	0	0	112.1	K97 L98 L103 V104 G233 M234 P237	K97-W100 PolarHBondContact O-NE1 3.3Å; K97-W100 VanDerWaalsContact O-NE1 3.12Å; L98-W100 VanDerWaalsContact C-N 3.25Å; L98-W100 PolarHBondContact O-N 3.03Å; W100-L103 PolarHBondContact O-N 2.87Å; W100-V104 HydrophobicContact CE3-CG2 4.17Å; W100-V104 WeakPolarHBondContact O-CB 3.42Å; W100-V104 VanDerWaalsContact O-CG2 3.28Å; W100-V104 WeakPolarHBondContact O-CG2 3.05Å; W100-V104 PolarHBondContact O-N 2.83Å; W100-G233 WeakPolarHBondContact CB-O 3.45Å; W100-G233 PolarHBondContact N-O 3.1Å; W100-M234 WeakPolarHBondContact CA-O 3.22Å; W100-M234 WeakPolarHBondContact CB-O 3.21Å; W100-P237 HydrophobicContact CD2-CB 3.92Å; W100-P237 HydrophobicContact CE3-CB 4.15Å; W100-P237 HydrophobicContact CG-CB 4.24Å
101	V	92.6	Very high	92.8	Very high	12 Å²	12	26 Å²	26	7%	0.073	14%	0.135	C	C	.	.	H	α-helix	trans	-66.9	-45.4	174.5	-177.7	0	0	0	0	109.2	L98 L99 L103 V104 S105 A250 I253 V254	L98-V101 HydrophobicContact CD2-CG2 4.09Å; L98-V101 WeakPolarHBondContact O-CA 3.49Å; L98-V101 VanDerWaalsContact O-CB 3.32Å; L98-V101 WeakPolarHBondContact O-CB 3.49Å; L98-V101 PolarHBondContact O-N 3.32Å; L99-V101 VanDerWaalsContact C-N 3.29Å; L99-V101 PolarHBondContact O-N 2.9Å; V101-L103 VanDerWaalsContact C-N 3.34Å; V101-L103 PolarHBondContact O-N 3.2Å; V101-V104 PolarHBondContact O-N 2.98Å; V101-S105 WeakPolarHBondContact O-CB 3.4Å; V101-S105 PolarHBondContact O-N 3.43Å; V101-S105 PolarHBondContact O-OG 3.32Å; V101-A250 HydrophobicContact CG1-CB 4.36Å; V101-A250 HydrophobicContact CG2-CB 4.33Å; V101-I253 HydrophobicContact CG1-CB 4.4Å; V101-I253 HydrophobicContact CG1-CG2 4.28Å; V101-V254 HydrophobicContact CG1-CG2 4.12Å
102	L	94.1	Very high	92.9	Very high	0 Å²	0	26.7 Å²	26.7	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-57.2	-46.3	174.2	176.8	64.5	0	0	0	111.7	L98 L99 T106 I253 V257 F302 N305 V306 V309	L98-L102 PolarHBondContact O-N 3.47Å; L98-L102 VanDerWaalsContact O-N 3.16Å; L99-L102 HydrophobicContact CD2-CD2 4.35Å; L99-L102 WeakPolarHBondContact O-CB 3.03Å; L99-L102 PolarHBondContact O-N 3.06Å; L102-T106 WeakPolarHBondContact O-CB 3.25Å; L102-T106 PolarHBondContact O-N 2.79Å; L102-T106 PolarHBondContact O-OG1 3.18Å; L102-I253 HydrophobicContact CB-CG2 4.07Å; L102-I253 HydrophobicContact CD1-CG2 4.06Å; L102-V257 HydrophobicContact CD1-CG2 3.7Å; L102-F302 HydrophobicContact CD2-CE2 4.27Å; L102-F302 HydrophobicContact CG-CD2 4.23Å; L102-F302 HydrophobicContact CG-CE2 4.03Å; L102-N305 HydrophobicContact CD1-CB 4.04Å; L102-N305 HydrophobicContact CD2-CB 3.77Å; L102-N305 HydrophobicContact CG-CB 4.41Å; L102-V306 HydrophobicContact CD2-CG2 4.11Å; L102-V309 HydrophobicContact CD2-CG2 3.94Å
103	L	95.5	Very high	93.1	Very high	39 Å²	39	26.2 Å²	26.2	20%	0.204	13%	0.134	C	C	.	.	H	α-helix	trans	-61.2	-51	177.4	176.5	63.1	0	0	0	111.7	L99 W100 V101 T106 V107 M234 F235 F302	L99-L103 PolarHBondContact O-N 3.29Å; W100-L103 PolarHBondContact O-N 2.87Å; V101-L103 VanDerWaalsContact C-N 3.34Å; V101-L103 PolarHBondContact O-N 3.2Å; L103-T106 PolarHBondContact O-N 2.99Å; L103-V107 HydrophobicContact CD1-CG2 4.42Å; L103-V107 WeakPolarHBondContact O-CG2 3.33Å; L103-V107 PolarHBondContact O-N 3Å; L103-M234 WeakPolarHBondContact CD2-O 3.07Å; L103-F235 HydrophobicContact CD2-CD1 4.29Å; L103-F235 HydrophobicContact CD2-CE1 4.16Å; L103-F302 HydrophobicContact CB-CE2 3.89Å; L103-F302 HydrophobicContact CB-CZ 3.9Å; L103-F302 HydrophobicContact CD1-CE1 3.91Å; L103-F302 HydrophobicContact CD1-CE2 3.95Å; L103-F302 HydrophobicContact CD1-CZ 3.51Å; L103-F302 HydrophobicContact CG-CZ 4.25Å
104	V	93.8	Very high	93.4	Very high	66 Å²	66	26.8 Å²	26.8	40%	0.4	14%	0.135	S	C	.	.	H	α-helix	trans	-63.3	-43.4	-179.7	169.8	0	0	0	0	111	W100 V101 T106 V107 I108	W100-V104 HydrophobicContact CE3-CG2 4.17Å; W100-V104 WeakPolarHBondContact O-CB 3.42Å; W100-V104 VanDerWaalsContact O-CG2 3.28Å; W100-V104 WeakPolarHBondContact O-CG2 3.05Å; W100-V104 PolarHBondContact O-N 2.83Å; V101-V104 PolarHBondContact O-N 2.98Å; V104-T106 VanDerWaalsContact C-N 3.33Å; V104-T106 PolarHBondContact O-N 2.81Å; V104-V107 PolarHBondContact O-N 3.43Å; V104-I108 HydrophobicContact CG1-CD1 3.74Å; V104-I108 HydrophobicContact CG1-CG1 4.35Å; V104-I108 VanDerWaalsContact O-CG1 3.29Å; V104-I108 WeakPolarHBondContact O-CG1 3.43Å; V104-I108 PolarHBondContact O-N 3.12Å
105	S	92.8	Very high	93.7	Very high	3 Å²	3	27 Å²	27	2%	0.021	14%	0.136	C	C	.	.	H	α-helix	trans	-60.9	-40.9	175.7	-65.2	0	0	0	0	111.8	V101 I108 G109 V254	V101-S105 WeakPolarHBondContact O-CB 3.4Å; V101-S105 PolarHBondContact O-N 3.43Å; V101-S105 PolarHBondContact O-OG 3.32Å; S105-I108 PolarHBondContact O-N 2.73Å; S105-G109 PolarHBondContact O-N 3.47Å; S105-V254 VanDerWaalsContact OG-CG2 3.31Å; S105-V254 WeakPolarHBondContact OG-CG2 3.49Å
106	T	95	Very high	93.9	Very high	12 Å²	12	27 Å²	27	7%	0.074	14%	0.135	C	C	.	.	H	α-helix	trans	-67.7	-40	177.5	-54.7	0	0	0	0	111.2	L102 L103 V104 G109 L110 F302	L102-T106 WeakPolarHBondContact O-CB 3.25Å; L102-T106 PolarHBondContact O-N 2.79Å; L102-T106 PolarHBondContact O-OG1 3.18Å; L103-T106 PolarHBondContact O-N 2.99Å; V104-T106 VanDerWaalsContact C-N 3.33Å; V104-T106 PolarHBondContact O-N 2.81Å; T106-G109 PolarHBondContact O-N 3.2Å; T106-L110 PolarHBondContact O-N 3Å; T106-F302 HydrophobicContact CG2-CB 3.87Å; T106-F302 HydrophobicContact CG2-CD2 4.25Å; T106-F302 HydrophobicContact CG2-CG 4.35Å
107	V	95.3	Very high	94.1	Very high	74 Å²	74	26.5 Å²	26.5	45%	0.448	13%	0.133	S	C	.	.	H	α-helix	trans	-62.4	-49.1	174	171.4	0	0	0	0	110.5	L103 V104 G109 L110 L111	L103-V107 HydrophobicContact CD1-CG2 4.42Å; L103-V107 WeakPolarHBondContact O-CG2 3.33Å; L103-V107 PolarHBondContact O-N 3Å; V104-V107 PolarHBondContact O-N 3.43Å; V107-G109 VanDerWaalsContact C-N 3.28Å; V107-G109 PolarHBondContact O-N 3.08Å; V107-L110 WeakPolarHBondContact O-CB 3.4Å; V107-L110 PolarHBondContact O-N 3.19Å; V107-L111 WeakPolarHBondContact O-CG 3.39Å; V107-L111 PolarHBondContact O-N 3.03Å
108	I	93.5	Very high	94.3	Very high	43 Å²	43	26.2 Å²	26.2	22%	0.221	13%	0.131	C	C	.	.	H	α-helix	trans	-58.8	-43.1	175.9	-67.7	168.5	0	0	0	110.2	V104 S105 L110 L111 L112 I258 V477	V104-I108 HydrophobicContact CG1-CD1 3.74Å; V104-I108 HydrophobicContact CG1-CG1 4.35Å; V104-I108 VanDerWaalsContact O-CG1 3.29Å; V104-I108 WeakPolarHBondContact O-CG1 3.43Å; V104-I108 PolarHBondContact O-N 3.12Å; S105-I108 PolarHBondContact O-N 2.73Å; I108-L110 PolarHBondContact O-N 3.31Å; I108-L111 WeakPolarHBondContact O-CB 3.17Å; I108-L111 PolarHBondContact O-N 3.45Å; I108-L111 VanDerWaalsContact O-N 3.1Å; I108-L112 HydrophobicContact CG2-CD1 3.87Å; I108-L112 HydrophobicContact CG2-CG 4.32Å; I108-L112 WeakPolarHBondContact O-CG 3.4Å; I108-L112 PolarHBondContact O-N 3.17Å; I108-I258 HydrophobicContact CB-CD1 4.26Å; I108-I258 HydrophobicContact CG2-CD1 3.71Å; I108-V477 HydrophobicContact CG2-CG1 3.83Å; I108-V477 HydrophobicContact CG2-CG2 4.13Å
109	G	94.1	Very high	94.5	Very high	0 Å²	0	26 Å²	26	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-52.8	-53.5	172.8	0	0	0	0	0	111.8	Y78 S105 T106 V107 L111 L112 Q113	Y78-G109 WeakPolarHBondContact OH-CA 3.4Å; S105-G109 PolarHBondContact O-N 3.47Å; T106-G109 PolarHBondContact O-N 3.2Å; V107-G109 VanDerWaalsContact C-N 3.28Å; V107-G109 PolarHBondContact O-N 3.08Å; G109-L111 VanDerWaalsContact C-N 3.26Å; G109-L111 PolarHBondContact O-N 3.47Å; G109-L112 PolarHBondContact O-N 3.24Å; G109-L112 VanDerWaalsContact O-N 3.13Å; G109-Q113 WeakPolarHBondContact O-CB 3.37Å; G109-Q113 WeakPolarHBondContact O-CG 3.34Å; G109-Q113 PolarHBondContact O-N 3.15Å
110	L	95.8	Very high	94.5	Very high	31 Å²	31	26.1 Å²	26.1	16%	0.162	13%	0.132	C	C	.	.	H	α-helix	trans	-56	-39.9	175.7	175.1	63.4	0	0	0	112.4	T106 V107 I108 Q113 R114 F291 L298	T106-L110 PolarHBondContact O-N 3Å; V107-L110 WeakPolarHBondContact O-CB 3.4Å; V107-L110 PolarHBondContact O-N 3.19Å; I108-L110 PolarHBondContact O-N 3.31Å; L110-Q113 PolarHBondContact O-N 3.46Å; L110-R114 WeakPolarHBondContact O-CB 3.49Å; L110-R114 PolarHBondContact O-N 3.41Å; L110-F291 HydrophobicContact CD1-CE2 4.28Å; L110-F291 HydrophobicContact CD2-CE2 4.37Å; L110-F291 HydrophobicContact CG-CE2 4.25Å; L110-L298 HydrophobicContact CB-CD1 3.71Å; L110-L298 HydrophobicContact CD1-CD1 3.87Å; L110-L298 HydrophobicContact CG-CD1 4.39Å
111	L	94.2	Very high	94.5	Very high	56 Å²	56	22.7 Å²	22.7	29%	0.293	12%	0.119	S	C	.	.	H	α-helix	trans	-65.6	-42.6	177.9	-63.7	-168.9	0	0	0	112.3	V107 I108 G109 R114 L115 W470	V107-L111 WeakPolarHBondContact O-CG 3.39Å; V107-L111 PolarHBondContact O-N 3.03Å; I108-L111 WeakPolarHBondContact O-CB 3.17Å; I108-L111 PolarHBondContact O-N 3.45Å; I108-L111 VanDerWaalsContact O-N 3.1Å; G109-L111 VanDerWaalsContact C-N 3.26Å; G109-L111 PolarHBondContact O-N 3.47Å; L111-R114 WeakPolarHBondContact O-CB 3.21Å; L111-R114 PolarHBondContact O-N 3.19Å; L111-L115 PolarHBondContact O-N 3.15Å; L111-W470 HydrophobicContact CB-CH2 4.37Å; L111-W470 HydrophobicContact CB-CZ3 3.94Å; L111-W470 HydrophobicContact CD1-CH2 3.98Å; L111-W470 HydrophobicContact CD1-CZ3 3.82Å; L111-W470 HydrophobicContact CD2-CH2 3.51Å; L111-W470 HydrophobicContact CD2-CZ3 3.96Å; L111-W470 HydrophobicContact CG-CH2 4.11Å; L111-W470 HydrophobicContact CG-CZ3 4.07Å
112	L	94.1	Very high	94.6	Very high	13 Å²	13	23 Å²	23	7%	0.068	12%	0.121	C	C	.	.	H	α-helix	trans	-68.2	-41.4	176.6	-66.3	167.7	0	0	0	111.5	I108 G109 R114 L115 A116 I258 L448	I108-L112 HydrophobicContact CG2-CD1 3.87Å; I108-L112 HydrophobicContact CG2-CG 4.32Å; I108-L112 WeakPolarHBondContact O-CG 3.4Å; I108-L112 PolarHBondContact O-N 3.17Å; G109-L112 PolarHBondContact O-N 3.24Å; G109-L112 VanDerWaalsContact O-N 3.13Å; L112-R114 VanDerWaalsContact C-N 3.26Å; L112-R114 PolarHBondContact O-N 3.29Å; L112-L115 WeakPolarHBondContact O-CA 3.42Å; L112-L115 WeakPolarHBondContact O-CB 3.45Å; L112-L115 PolarHBondContact O-N 2.99Å; L112-A116 PolarHBondContact O-N 3.21Å; L112-I258 HydrophobicContact CD1-CD1 4.11Å; L112-I258 HydrophobicContact CD1-CG2 3.64Å; L112-L448 HydrophobicContact CD1-CD2 3.34Å; L112-L448 HydrophobicContact CD2-CD2 3.63Å; L112-L448 HydrophobicContact CG-CD2 4.03Å
113	Q	95.5	Very high	94.5	Very high	2 Å²	2	24.1 Å²	24.1	1%	0.009	13%	0.128	C	C	.	.	H	α-helix	trans	-63	-34.6	175.5	-69	-61.9	-6.4	0	0	111.9	M74 G109 L110 L115 A116 A117 N262 H266 L298	M74-Q113 HydrophobicContact CE-CB 4.09Å; M74-Q113 HydrophobicContact CE-CG 4.01Å; M74-Q113 HydrophobicContact CG-CG 4.36Å; M74-Q113 HydrophobicContact SD-CB 4.4Å; M74-Q113 HydrophobicContact SD-CG 3.68Å; G109-Q113 WeakPolarHBondContact O-CB 3.37Å; G109-Q113 WeakPolarHBondContact O-CG 3.34Å; G109-Q113 PolarHBondContact O-N 3.15Å; L110-Q113 PolarHBondContact O-N 3.46Å; Q113-L115 VanDerWaalsContact C-N 3.32Å; Q113-L115 PolarHBondContact O-N 3.21Å; Q113-A116 WeakPolarHBondContact O-CB 3.34Å; Q113-A116 PolarHBondContact O-N 3.1Å; Q113-A117 WeakPolarHBondContact O-CB 3.34Å; Q113-A117 PolarHBondContact O-N 3.41Å; Q113-N262 PolarHBondContact NE2-ND2 3.12Å; Q113-H266 PolarHBondContact O-ND1 2.94Å; Q113-H266 PolarHBondContact OE1-ND1 3.48Å; Q113-L298 HydrophobicContact CG-CD1 4.44Å
114	R	95.2	Very high	94.2	Very high	79 Å²	79	22.5 Å²	22.5	30%	0.298	12%	0.121	S	C	.	.	H	α-helix	trans	-62.6	-38.4	170.7	-176.2	-173.3	-178.4	-173.8	0.7	112.1	L110 L111 L112 R118 F291	L110-R114 WeakPolarHBondContact O-CB 3.49Å; L110-R114 PolarHBondContact O-N 3.41Å; L111-R114 WeakPolarHBondContact O-CB 3.21Å; L111-R114 PolarHBondContact O-N 3.19Å; L112-R114 VanDerWaalsContact C-N 3.26Å; L112-R114 PolarHBondContact O-N 3.29Å; R114-R118 VanDerWaalsContact O-CB 3.32Å; R114-R118 WeakPolarHBondContact O-CB 3.4Å; R114-R118 WeakPolarHBondContact O-CG 3.3Å; R114-R118 PolarHBondContact O-N 2.89Å; R114-F291 HydrophobicContact CB-CD2 4.14Å; R114-F291 HydrophobicContact CG-CD2 3.83Å; R114-F291 HydrophobicContact CG-CE2 4.39Å
115	L	95.1	Very high	94.1	Very high	6 Å²	6	21.1 Å²	21.1	3%	0.031	11%	0.11	C	C	.	.	H	α-helix	trans	-66.6	-43.9	175.5	-62.9	-178.9	0	0	0	110.9	L111 L112 Q113 R118 L119 I451 L452 T455	L111-L115 PolarHBondContact O-N 3.15Å; L112-L115 WeakPolarHBondContact O-CA 3.42Å; L112-L115 WeakPolarHBondContact O-CB 3.45Å; L112-L115 PolarHBondContact O-N 2.99Å; Q113-L115 VanDerWaalsContact C-N 3.32Å; Q113-L115 PolarHBondContact O-N 3.21Å; L115-R118 PolarHBondContact O-N 3.16Å; L115-L119 PolarHBondContact O-N 3.22Å; L115-I451 HydrophobicContact CB-CG1 3.89Å; L115-L452 HydrophobicContact CD1-CD1 4.35Å; L115-T455 HydrophobicContact CB-CG2 4.22Å
116	A	95.8	Very high	94.1	Very high	0 Å²	0	21.2 Å²	21.2	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-57	-52	175.2	0	0	0	0	0	112.4	L112 Q113 R118 L119 G120 I263 H266 S267 I451	L112-A116 PolarHBondContact O-N 3.21Å; Q113-A116 WeakPolarHBondContact O-CB 3.34Å; Q113-A116 PolarHBondContact O-N 3.1Å; A116-R118 PolarHBondContact O-N 3.07Å; A116-L119 PolarHBondContact O-N 2.7Å; A116-G120 PolarHBondContact O-N 2.76Å; A116-G120 VanDerWaalsContact O-N 3.16Å; A116-I263 HydrophobicContact CB-CG2 3.96Å; A116-I263 WeakPolarHBondContact CB-O 3.37Å; A116-H266 HydrophobicContact CB-CB 4.44Å; A116-S267 WeakPolarHBondContact O-CA 3.22Å; A116-S267 WeakPolarHBondContact O-CB 3.38Å; A116-I451 HydrophobicContact CB-CD1 4.49Å
117	A	95.3	Very high	94.1	Very high	4 Å²	4	20.7 Å²	20.7	3%	0.033	11%	0.107	C	C	.	.	H	α-helix	trans	-59.6	-45.3	177.2	0	0	0	0	0	111.7	Q113 L119 G120 V121 V270	Q113-A117 WeakPolarHBondContact O-CB 3.34Å; Q113-A117 PolarHBondContact O-N 3.41Å; A117-L119 PolarHBondContact O-N 3.18Å; A117-G120 PolarHBondContact O-N 3.36Å; A117-V121 WeakPolarHBondContact O-CB 3.36Å; A117-V121 VanDerWaalsContact O-CG2 3.23Å; A117-V121 WeakPolarHBondContact O-CG2 3.39Å; A117-V121 PolarHBondContact O-N 3.26Å; A117-V270 HydrophobicContact CB-CG1 3.88Å
118	R	95.2	Very high	94.1	Very high	29 Å²	29	17.1 Å²	17.1	11%	0.109	9%	0.086	C	C	.	.	H	α-helix	trans	-62	-41.2	178.7	-78.5	175.7	68.7	-152.6	0.1	112.6	R114 L115 A116 G120 V121 V122 N287 M461 F464 N466	R114-R118 VanDerWaalsContact O-CB 3.32Å; R114-R118 WeakPolarHBondContact O-CB 3.4Å; R114-R118 WeakPolarHBondContact O-CG 3.3Å; R114-R118 PolarHBondContact O-N 2.89Å; L115-R118 PolarHBondContact O-N 3.16Å; A116-R118 PolarHBondContact O-N 3.07Å; R118-G120 VanDerWaalsContact C-N 3.34Å; R118-V121 PolarHBondContact O-N 2.93Å; R118-V122 VanDerWaalsContact O-CB 3.29Å; R118-V122 WeakPolarHBondContact O-CB 3.23Å; R118-V122 WeakPolarHBondContact O-CG2 3.48Å; R118-V122 PolarHBondContact O-N 3.38Å; R118-N287 WeakPolarHBondContact CG-OD1 3.37Å; R118-M461 HydrophobicContact CB-CE 4.22Å; R118-F464 PolarHBondContact NH2-O 3.17Å; R118-N466 PolarHBondContact NH1-OD1 3.4Å
119	L	95.1	Very high	94.1	Very high	0 Å²	0	17.2 Å²	17.2	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-58.6	-49.7	176.3	-174.6	74.1	0	0	0	110.2	L115 A116 A117 V121 T123 L127 V130 I451 F454 T455 I460 M461	L115-L119 PolarHBondContact O-N 3.22Å; A116-L119 PolarHBondContact O-N 2.7Å; A117-L119 PolarHBondContact O-N 3.18Å; L119-V121 PolarHBondContact O-N 3.09Å; L119-T123 HydrophobicContact CD1-CG2 3.85Å; L119-T123 HydrophobicContact CG-CG2 4.43Å; L119-T123 WeakPolarHBondContact O-CB 3.21Å; L119-T123 WeakPolarHBondContact O-CG2 3.29Å; L119-T123 PolarHBondContact O-N 3.2Å; L119-T123 PolarHBondContact O-OG1 2.96Å; L119-L127 HydrophobicContact CD2-CB 4.02Å; L119-L127 HydrophobicContact CD2-CD1 3.6Å; L119-L127 HydrophobicContact CD2-CG 4.42Å; L119-V130 HydrophobicContact CD2-CG2 4.31Å; L119-I451 HydrophobicContact CB-CD1 3.95Å; L119-I451 HydrophobicContact CD2-CD1 3.69Å; L119-I451 HydrophobicContact CG-CD1 4.4Å; L119-F454 HydrophobicContact CD1-CB 4.05Å; L119-T455 HydrophobicContact CB-CG2 3.99Å; L119-T455 HydrophobicContact CD1-CG2 4.17Å; L119-I460 HydrophobicContact CD1-CG2 4.16Å; L119-M461 HydrophobicContact CD1-SD 4.03Å
120	G	93.8	Very high	94.1	Very high	2 Å²	2	17.3 Å²	17.3	2%	0.021	9%	0.086	C	C	.	.	H	α-helix	trans	-61.6	-43.7	179.3	0	0	0	0	0	113.6	A116 A117 R118 G124 M125 S267	A116-G120 PolarHBondContact O-N 2.76Å; A116-G120 VanDerWaalsContact O-N 3.16Å; A117-G120 PolarHBondContact O-N 3.36Å; R118-G120 VanDerWaalsContact C-N 3.34Å; G120-G124 VanDerWaalsContact O-CA 3.24Å; G120-G124 WeakPolarHBondContact O-CA 3.22Å; G120-G124 PolarHBondContact O-N 2.9Å; G120-M125 WeakPolarHBondContact CA-O 3.43Å; G120-S267 WeakPolarHBondContact CA-O 3.46Å
121	V	93.8	Very high	93.9	Very high	6 Å²	6	15.8 Å²	15.8	4%	0.036	8%	0.078	C	C	.	.	H	α-helix	trans	-69.8	-42.6	-179	174.4	0	0	0	0	112.3	A117 R118 L119 V270 V283 A286 F290	A117-V121 WeakPolarHBondContact O-CB 3.36Å; A117-V121 VanDerWaalsContact O-CG2 3.23Å; A117-V121 WeakPolarHBondContact O-CG2 3.39Å; A117-V121 PolarHBondContact O-N 3.26Å; R118-V121 PolarHBondContact O-N 2.93Å; L119-V121 PolarHBondContact O-N 3.09Å; V121-V270 HydrophobicContact CG2-CB 3.98Å; V121-V270 HydrophobicContact CG2-CG2 4.04Å; V121-V283 HydrophobicContact CG1-CG1 4.24Å; V121-A286 HydrophobicContact CG1-CB 3.88Å; V121-F290 HydrophobicContact CG2-CD2 3.51Å; V121-F290 HydrophobicContact CG2-CE2 3.52Å
122	V	94	Very high	93.9	Very high	17 Å²	17	14.9 Å²	14.9	10%	0.103	7%	0.073	C	C	.	.	H	α-helix	trans	-77.4	-50.1	-175.2	173.7	0	0	0	0	111.3	R118 V283 M461 F464	R118-V122 VanDerWaalsContact O-CB 3.29Å; R118-V122 WeakPolarHBondContact O-CB 3.23Å; R118-V122 WeakPolarHBondContact O-CG2 3.48Å; R118-V122 PolarHBondContact O-N 3.38Å; V122-V283 HydrophobicContact CG2-CG1 3.84Å; V122-M461 HydrophobicContact CB-CE 4.1Å; V122-M461 HydrophobicContact CB-SD 4.15Å; V122-M461 HydrophobicContact CG1-CE 4.31Å; V122-M461 HydrophobicContact CG1-SD 4.18Å; V122-M461 HydrophobicContact CG2-CE 3.87Å; V122-F464 HydrophobicContact CG1-CB 4.24Å; V122-F464 HydrophobicContact CG1-CD2 4.18Å; V122-F464 HydrophobicContact CG2-CB 3.83Å; V122-F464 HydrophobicContact CG2-CD2 4.16Å; V122-F464 HydrophobicContact CG2-CG 4Å
123	T	90.9	Very high	93.7	Very high	24 Å²	24	21.9 Å²	21.9	15%	0.147	10%	0.099	C	C	.	.	H	α-helix	trans	-81.5	-25.5	-174.9	67.8	0	0	0	0	112.1	L119 M125 I460 M461	L119-T123 HydrophobicContact CD1-CG2 3.85Å; L119-T123 HydrophobicContact CG-CG2 4.43Å; L119-T123 WeakPolarHBondContact O-CB 3.21Å; L119-T123 WeakPolarHBondContact O-CG2 3.29Å; L119-T123 PolarHBondContact O-N 3.2Å; L119-T123 PolarHBondContact O-OG1 2.96Å; T123-M125 PolarHBondContact O-N 3.03Å; T123-M125 PolarHBondContact OG1-N 3.33Å; T123-M125 PolarHBondContact OG1-O 2.95Å; T123-I460 HydrophobicContact CG2-CG2 3.46Å; T123-I460 VanDerWaalsContact CG2-CG2 3.46Å; T123-M461 HydrophobicContact CG2-SD 4.44Å
124	G	89.7	Confident	93.4	Very high	6 Å²	6	24.9 Å²	24.9	6%	0.062	11%	0.113	C	C	.	.	S	Bend	trans	73.5	2.5	-169	0	0	0	0	0	114.9	G120 K271	G120-G124 VanDerWaalsContact O-CA 3.24Å; G120-G124 WeakPolarHBondContact O-CA 3.22Å; G120-G124 PolarHBondContact O-N 2.9Å; G124-K271 WeakPolarHBondContact O-CE 3.28Å; G124-K271 PolarHBondContact O-NZ 3.3Å
125	M	91.1	Very high	93.2	Very high	37 Å²	37	21.8 Å²	21.8	18%	0.182	10%	0.101	C	C	.	.	S	Bend	trans	-113.6	145.4	176.6	-65.6	179.7	-74.2	0	0	109.4	G120 T123 E129 V130 R133	G120-M125 WeakPolarHBondContact CA-O 3.43Å; T123-M125 PolarHBondContact O-N 3.03Å; T123-M125 PolarHBondContact OG1-N 3.33Å; T123-M125 PolarHBondContact OG1-O 2.95Å; M125-E129 WeakPolarHBondContact CA-OE2 3.42Å; M125-E129 HydrophobicContact CB-CB 4.01Å; M125-E129 WeakPolarHBondContact CB-OE2 3.5Å; M125-E129 HydrophobicContact CG-CB 4.44Å; M125-V130 HydrophobicContact CB-CG2 3.8Å; M125-V130 HydrophobicContact CE-CG2 4.19Å; M125-R133 PolarHBondContact SD-NH1 2.89Å
126	H	93.9	Very high	92.9	Very high	5 Å²	5	25 Å²	25	2%	0.023	12%	0.123	C	C	.	.			trans	-83.7	165.1	171.2	58.5	70	0	0	0	111.1	A128 E129 V130 S267 A268 K271 F390	H126-A128 VanDerWaalsContact C-N 3.27Å; H126-A128 PolarHBondContact O-N 3.27Å; H126-A128 VanDerWaalsContact O-N 3.14Å; H126-E129 VanDerWaalsContact CD2-CD 3.45Å; H126-E129 IonicContact CD2-OE1 2.89Å; H126-E129 IonicContact CD2-OE2 3.07Å; H126-E129 PolarHBondContact CD2-OE2 2.96Å; H126-E129 VanDerWaalsContact CE1-CG 3.43Å; H126-E129 WeakPolarHBondContact CE1-CG 3.47Å; H126-E129 IonicContact CE1-OE1 2.87Å; H126-E129 IonicContact CG-OE2 2.93Å; H126-E129 PolarHBondContact N-OE2 3.43Å; H126-E129 PolarHBondContact ND1-N 3.42Å; H126-E129 VanDerWaalsContact NE2-CD 3.35Å; H126-E129 IonicContact NE2-OE1 2.88Å; H126-E129 PolarHBondContact NE2-OE1 3.47Å; H126-E129 IonicContact NE2-OE2 2.9Å; H126-E129 WeakPolarHBondContact O-CB 3.46Å; H126-E129 PolarHBondContact O-N 3.42Å; H126-V130 PolarHBondContact O-N 2.97Å; H126-V130 VanDerWaalsContact O-N 3.14Å; H126-S267 WeakPolarHBondContact CB-OG 3.12Å; H126-A268 HydrophobicContact CB-CB 3.69Å; H126-K271 HydrophobicContact CB-CD 4.32Å; H126-F390 PolarHBondContact CE1-O 3.04Å; H126-F390 AromaticContact NE2-CD1 3.92Å
127	L	94.7	Very high	92.6	Very high	0 Å²	0	28.8 Å²	28.8	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-54.3	-41.3	-171.4	-178.8	60	0	0	0	113.1	L119 E129 V130 C131 I263 Y264 S267 P450 I451 F454	L119-L127 HydrophobicContact CD2-CB 4.02Å; L119-L127 HydrophobicContact CD2-CD1 3.6Å; L119-L127 HydrophobicContact CD2-CG 4.42Å; L127-E129 PolarHBondContact O-N 3.22Å; L127-V130 PolarHBondContact O-N 3.32Å; L127-C131 PolarHBondContact O-N 2.95Å; L127-C131 PolarHBondContact O-SG 3.3Å; L127-I263 HydrophobicContact CD2-CG2 3.9Å; L127-Y264 HydrophobicContact CB-CD1 3.77Å; L127-Y264 HydrophobicContact CB-CE1 4Å; L127-Y264 HydrophobicContact CB-CG 4.49Å; L127-Y264 HydrophobicContact CD2-CD1 3.84Å; L127-Y264 HydrophobicContact CD2-CD2 4.24Å; L127-Y264 HydrophobicContact CD2-CE1 3.59Å; L127-Y264 HydrophobicContact CD2-CE2 4Å; L127-Y264 HydrophobicContact CD2-CG 4.15Å; L127-Y264 HydrophobicContact CG-CD1 3.82Å; L127-Y264 HydrophobicContact CG-CE1 3.52Å; L127-S267 PolarHBondContact N-OG 3.42Å; L127-P450 HydrophobicContact CD1-CB 4.19Å; L127-I451 HydrophobicContact CD1-CB 4.41Å; L127-I451 HydrophobicContact CD1-CD1 4.12Å; L127-I451 HydrophobicContact CD2-CB 4.1Å; L127-I451 HydrophobicContact CD2-CD1 4.39Å; L127-F454 HydrophobicContact CD1-CD2 3.82Å; L127-F454 HydrophobicContact CD1-CE2 4.35Å
128	A	94.6	Very high	92.5	Very high	0 Å²	0	33.6 Å²	33.6	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-64.2	-37.3	177.9	0	0	0	0	0	113.9	H126 C131 N132 Y264 G394 F395	H126-A128 VanDerWaalsContact C-N 3.27Å; H126-A128 PolarHBondContact O-N 3.27Å; H126-A128 VanDerWaalsContact O-N 3.14Å; A128-C131 PolarHBondContact O-N 2.92Å; A128-N132 WeakPolarHBondContact O-CB 3.46Å; A128-N132 PolarHBondContact O-N 3.5Å; A128-Y264 HydrophobicContact CB-CD1 3.96Å; A128-Y264 HydrophobicContact CB-CE1 4.29Å; A128-G394 CarbonylContact O-C 3.42Å; A128-F395 HydrophobicContact CB-CD2 3.5Å; A128-F395 HydrophobicContact CB-CE2 3.6Å; A128-F395 HydrophobicContact CB-CG 4.27Å; A128-F395 HydrophobicContact CB-CZ 4.42Å
129	E	94.2	Very high	92.3	Very high	44 Å²	44	33.1 Å²	33.1	21%	0.206	18%	0.175	C	C	.	.	H	α-helix	trans	-65.7	-41.6	174.6	-77.2	161.3	166	0	0	110.4	M125 H126 L127 N132 R133 K271	M125-E129 WeakPolarHBondContact CA-OE2 3.42Å; M125-E129 HydrophobicContact CB-CB 4.01Å; M125-E129 WeakPolarHBondContact CB-OE2 3.5Å; M125-E129 HydrophobicContact CG-CB 4.44Å; H126-E129 VanDerWaalsContact CD2-CD 3.45Å; H126-E129 IonicContact CD2-OE1 2.89Å; H126-E129 IonicContact CD2-OE2 3.07Å; H126-E129 PolarHBondContact CD2-OE2 2.96Å; H126-E129 VanDerWaalsContact CE1-CG 3.43Å; H126-E129 WeakPolarHBondContact CE1-CG 3.47Å; H126-E129 IonicContact CE1-OE1 2.87Å; H126-E129 IonicContact CG-OE2 2.93Å; H126-E129 PolarHBondContact N-OE2 3.43Å; H126-E129 PolarHBondContact ND1-N 3.42Å; H126-E129 VanDerWaalsContact NE2-CD 3.35Å; H126-E129 IonicContact NE2-OE1 2.88Å; H126-E129 PolarHBondContact NE2-OE1 3.47Å; H126-E129 IonicContact NE2-OE2 2.9Å; H126-E129 WeakPolarHBondContact O-CB 3.46Å; H126-E129 PolarHBondContact O-N 3.42Å; L127-E129 PolarHBondContact O-N 3.22Å; E129-N132 PolarHBondContact O-N 2.93Å; E129-R133 PolarHBondContact O-N 3.4Å; E129-R133 VanDerWaalsContact O-N 3.1Å; E129-K271 VanDerWaalsContact CD-NZ 3.34Å; E129-K271 IonicContact OE1-NZ 2.79Å; E129-K271 PolarHBondContact OE1-NZ 2.98Å; E129-K271 IonicContact OE2-NZ 2.73Å; E129-K271 PolarHBondContact OE2-NZ 3.45Å
130	V	93.4	Very high	92.2	Very high	2 Å²	2	35.6 Å²	35.6	1%	0.012	18%	0.184	C	C	.	.	H	α-helix	trans	-64.8	-44.7	176.2	-178	0	0	0	0	110.6	L119 M125 H126 L127 N132 R133 Q134 F454 I460	L119-V130 HydrophobicContact CD2-CG2 4.31Å; M125-V130 HydrophobicContact CB-CG2 3.8Å; M125-V130 HydrophobicContact CE-CG2 4.19Å; H126-V130 PolarHBondContact O-N 2.97Å; H126-V130 VanDerWaalsContact O-N 3.14Å; L127-V130 PolarHBondContact O-N 3.32Å; V130-N132 VanDerWaalsContact C-N 3.26Å; V130-N132 PolarHBondContact O-N 3.34Å; V130-R133 PolarHBondContact O-N 3.32Å; V130-Q134 HydrophobicContact CG1-CG 4.01Å; V130-Q134 VanDerWaalsContact O-CB 3.3Å; V130-Q134 WeakPolarHBondContact O-CB 3.34Å; V130-Q134 WeakPolarHBondContact O-CG 3.42Å; V130-Q134 PolarHBondContact O-N 3.26Å; V130-F454 HydrophobicContact CB-CD2 4.37Å; V130-F454 HydrophobicContact CG1-CB 4.11Å; V130-F454 HydrophobicContact CG1-CD1 3.96Å; V130-F454 HydrophobicContact CG1-CD2 3.66Å; V130-F454 HydrophobicContact CG1-CE1 4.3Å; V130-F454 HydrophobicContact CG1-CE2 4Å; V130-F454 HydrophobicContact CG1-CG 3.64Å; V130-F454 HydrophobicContact CG1-CZ 4.32Å; V130-I460 HydrophobicContact CG1-CD1 4.1Å
131	C	93	Very high	92.2	Very high	0 Å²	0	39 Å²	39	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-56.9	-40.3	173.6	-71.6	0	0	0	0	111.9	L127 A128 Q134 Y135 L143 F395	L127-C131 PolarHBondContact O-N 2.95Å; L127-C131 PolarHBondContact O-SG 3.3Å; A128-C131 PolarHBondContact O-N 2.92Å; C131-Q134 PolarHBondContact O-N 3.22Å; C131-Y135 HydrophobicContact CB-CD2 4.01Å; C131-Y135 HydrophobicContact CB-CE2 4.43Å; C131-Y135 WeakPolarHBondContact O-CB 3.43Å; C131-Y135 PolarHBondContact O-N 2.95Å; C131-L143 HydrophobicContact CB-CD2 4.42Å; C131-F395 HydrophobicContact CB-CD1 4.16Å; C131-F395 HydrophobicContact CB-CE1 3.42Å; C131-F395 VanDerWaalsContact CB-CE1 3.42Å; C131-F395 HydrophobicContact CB-CZ 3.8Å
132	N	93.1	Very high	92.2	Very high	36 Å²	36	42.3 Å²	42.3	19%	0.193	22%	0.218	C	C	.	.	H	α-helix	trans	-66	-38.9	179.5	174.2	-78.9	0	0	0	113.4	A128 E129 V130 R140 G394 F395	A128-N132 WeakPolarHBondContact O-CB 3.46Å; A128-N132 PolarHBondContact O-N 3.5Å; E129-N132 PolarHBondContact O-N 2.93Å; V130-N132 VanDerWaalsContact C-N 3.26Å; V130-N132 PolarHBondContact O-N 3.34Å; N132-R140 WeakPolarHBondContact ND2-CD 3.47Å; N132-R140 PolarHBondContact ND2-NH1 2.99Å; N132-G394 WeakPolarHBondContact CB-O 3.46Å; N132-F395 PolarHBondContact ND2-O 3.48Å
133	R	90.9	Very high	92.2	Very high	160 Å²	160	41.5 Å²	41.5	60%	0.604	21%	0.213	S	C	*	.	H	α-helix	trans	-75.2	-30.4	177.9	-67.9	-175.2	-177.8	-169.4	2	113.1	M125 E129 V130	M125-R133 PolarHBondContact SD-NH1 2.89Å; E129-R133 PolarHBondContact O-N 3.4Å; E129-R133 VanDerWaalsContact O-N 3.1Å; V130-R133 PolarHBondContact O-N 3.32Å
134	Q	89.1	Confident	92.4	Very high	66 Å²	66	42.8 Å²	42.8	31%	0.308	22%	0.216	S	C	.	.	H	α-helix	trans	-98.9	-33	-170.7	-65.7	-62.9	-20.8	0	0	114.2	V130 C131 F454 I460	V130-Q134 HydrophobicContact CG1-CG 4.01Å; V130-Q134 VanDerWaalsContact O-CB 3.3Å; V130-Q134 WeakPolarHBondContact O-CB 3.34Å; V130-Q134 WeakPolarHBondContact O-CG 3.42Å; V130-Q134 PolarHBondContact O-N 3.26Å; C131-Q134 PolarHBondContact O-N 3.22Å; Q134-F454 HydrophobicContact CB-CE1 3.51Å; Q134-F454 HydrophobicContact CB-CZ 3.68Å; Q134-F454 HydrophobicContact CG-CD1 4.24Å; Q134-F454 HydrophobicContact CG-CE1 3.65Å; Q134-F454 HydrophobicContact CG-CZ 4.13Å; Q134-I460 HydrophobicContact CG-CD1 4.13Å
135	Y	89.6	Confident	92.6	Very high	13 Å²	13	47 Å²	47	5%	0.051	24%	0.236	C	C	.	.	S	Bend	trans	-95.2	141.4	-179.5	-69.2	-56	0	0	0	112	C131 L143 P450 F454 L519	C131-Y135 HydrophobicContact CB-CD2 4.01Å; C131-Y135 HydrophobicContact CB-CE2 4.43Å; C131-Y135 WeakPolarHBondContact O-CB 3.43Å; C131-Y135 PolarHBondContact O-N 2.95Å; Y135-L143 HydrophobicContact CD2-CD2 4.1Å; Y135-L143 HydrophobicContact CE2-CD2 3.93Å; Y135-P450 HydrophobicContact CE2-CB 4.4Å; Y135-P450 HydrophobicContact CE2-CG 4.37Å; Y135-F454 HydrophobicContact CD2-CZ 4.16Å; Y135-F454 AromaticContact CE2-CE2 3.98Å; Y135-F454 HydrophobicContact CE2-CE2 3.98Å; Y135-F454 AromaticContact CE2-CZ 3.6Å; Y135-F454 HydrophobicContact CE2-CZ 3.6Å; Y135-F454 AromaticContact CZ-CZ 3.84Å; Y135-L519 HydrophobicContact CE1-CD2 4Å; Y135-L519 HydrophobicContact CE2-CD2 4.4Å
136	P	89.9	Confident	92.8	Very high	75 Å²	75	47.1 Å²	47.1	49%	0.487	24%	0.237	S	C	.	.			trans	-66.3	162.7	173.1	26.2	-29.9	0	0	0	111.2	V138 P139 R140	P136-V138 VanDerWaalsContact C-N 3.31Å; P136-V138 PolarHBondContact O-N 2.96Å; P136-V138 VanDerWaalsContact O-N 3.11Å; P136-P139 HydrophobicContact CG-CG 3.95Å; P136-P139 WeakPolarHBondContact O-CD 3.38Å; P136-R140 VanDerWaalsContact O-CB 3.22Å; P136-R140 WeakPolarHBondContact O-CB 3.44Å; P136-R140 PolarHBondContact O-N 3.33Å
137	T	89.9	Confident	92.8	Very high	78 Å²	78	46.9 Å²	46.9	48%	0.479	24%	0.236	S	C	.	.	H	α-helix	trans	-51.3	-42.2	-169	-52	0	0	0	0	114.5	I141	T137-I141 HydrophobicContact CG2-CD1 3.73Å; T137-I141 HydrophobicContact CG2-CG1 4.5Å; T137-I141 VanDerWaalsContact O-CG1 3.24Å; T137-I141 WeakPolarHBondContact O-CG1 3.44Å; T137-I141 PolarHBondContact O-N 3.16Å
138	V	92	Very high	92.6	Very high	105 Å²	105	47.6 Å²	47.6	64%	0.636	24%	0.239	S	C	*	.	H	α-helix	trans	-70.5	-59.3	-175.6	174.3	0	0	0	0	112	P136 R140 I141 L142	P136-V138 VanDerWaalsContact C-N 3.31Å; P136-V138 PolarHBondContact O-N 2.96Å; P136-V138 VanDerWaalsContact O-N 3.11Å; V138-R140 PolarHBondContact O-N 2.95Å; V138-I141 PolarHBondContact O-N 2.66Å; V138-L142 HydrophobicContact CG1-CD1 4.26Å; V138-L142 WeakPolarHBondContact O-CG 3.39Å; V138-L142 PolarHBondContact O-N 3.04Å
139	P	91.4	Very high	92.5	Very high	19 Å²	19	51.1 Å²	51.1	12%	0.123	26%	0.257	C	S	.	.	H	α-helix	trans	-53.7	-37	172.6	-29.7	36.5	0	0	0	113.8	P136 L142 L143 F515 Y518	P136-P139 HydrophobicContact CG-CG 3.95Å; P136-P139 WeakPolarHBondContact O-CD 3.38Å; P139-L142 PolarHBondContact O-N 3.3Å; P139-L143 WeakPolarHBondContact O-CB 3.03Å; P139-L143 PolarHBondContact O-N 3.37Å; P139-F515 HydrophobicContact CB-CE2 4.1Å; P139-Y518 HydrophobicContact CB-CE1 3.73Å; P139-Y518 HydrophobicContact CG-CD1 4.49Å; P139-Y518 HydrophobicContact CG-CE1 3.6Å
140	R	93	Very high	92.4	Very high	52 Å²	52	49 Å²	49	20%	0.196	25%	0.248	C	C	.	.	H	α-helix	trans	-60.9	-48.3	177.2	-178.8	-176.1	71.4	-169.5	2.7	112.4	N132 P136 V138 L143 W144 F395	N132-R140 WeakPolarHBondContact ND2-CD 3.47Å; N132-R140 PolarHBondContact ND2-NH1 2.99Å; P136-R140 VanDerWaalsContact O-CB 3.22Å; P136-R140 WeakPolarHBondContact O-CB 3.44Å; P136-R140 PolarHBondContact O-N 3.33Å; V138-R140 PolarHBondContact O-N 2.95Å; R140-L143 PolarHBondContact O-N 3.5Å; R140-W144 WeakPolarHBondContact O-CB 3.44Å; R140-W144 PolarHBondContact O-N 2.71Å; R140-F395 WeakPolarHBondContact CD-O 3.41Å; R140-F395 HydrophobicContact CG-CD1 3.91Å
141	I	94.1	Very high	92.3	Very high	75 Å²	75	49 Å²	49	39%	0.385	25%	0.248	S	C	.	.	H	α-helix	trans	-68.6	-39.9	179.9	-68.4	168	0	0	0	110.7	T137 V138 L143 W144 L145 L396	T137-I141 HydrophobicContact CG2-CD1 3.73Å; T137-I141 HydrophobicContact CG2-CG1 4.5Å; T137-I141 VanDerWaalsContact O-CG1 3.24Å; T137-I141 WeakPolarHBondContact O-CG1 3.44Å; T137-I141 PolarHBondContact O-N 3.16Å; V138-I141 PolarHBondContact O-N 2.66Å; I141-L143 VanDerWaalsContact C-N 3.33Å; I141-L143 PolarHBondContact O-N 3.48Å; I141-W144 HydrophobicContact CG2-CE3 4.5Å; I141-W144 PolarHBondContact O-N 3.1Å; I141-L145 PolarHBondContact O-N 3.41Å; I141-L396 HydrophobicContact CG1-CD2 4.45Å
142	L	94.3	Very high	92.2	Very high	74 Å²	74	50.4 Å²	50.4	39%	0.387	26%	0.255	S	S	.	.	H	α-helix	trans	-62.1	-42.7	174.8	-68.3	178.1	0	0	0	111.4	V138 P139 L145 M146 F515	V138-L142 HydrophobicContact CG1-CD1 4.26Å; V138-L142 WeakPolarHBondContact O-CG 3.39Å; V138-L142 PolarHBondContact O-N 3.04Å; P139-L142 PolarHBondContact O-N 3.3Å; L142-L145 PolarHBondContact O-N 3.5Å; L142-M146 WeakPolarHBondContact O-CG 3.11Å; L142-M146 PolarHBondContact O-N 2.76Å; L142-M146 VanDerWaalsContact O-N 3.1Å; L142-F515 HydrophobicContact CB-CE1 3.99Å; L142-F515 HydrophobicContact CB-CE2 4.2Å; L142-F515 HydrophobicContact CB-CZ 3.77Å; L142-F515 HydrophobicContact CD1-CD2 4.43Å; L142-F515 HydrophobicContact CD1-CE2 4.41Å
143	L	94.1	Very high	92	Very high	0 Å²	0	48.9 Å²	48.9	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-63.9	-43.9	177.3	-170.1	57.6	0	0	0	111.4	C131 Y135 P139 R140 I141 L145 M146 I147 F395 F446 P450 F515 L519	C131-L143 HydrophobicContact CB-CD2 4.42Å; Y135-L143 HydrophobicContact CD2-CD2 4.1Å; Y135-L143 HydrophobicContact CE2-CD2 3.93Å; P139-L143 WeakPolarHBondContact O-CB 3.03Å; P139-L143 PolarHBondContact O-N 3.37Å; R140-L143 PolarHBondContact O-N 3.5Å; I141-L143 VanDerWaalsContact C-N 3.33Å; I141-L143 PolarHBondContact O-N 3.48Å; L143-L145 PolarHBondContact O-N 3.37Å; L143-M146 PolarHBondContact O-N 2.92Å; L143-I147 WeakPolarHBondContact O-CG1 3.12Å; L143-I147 PolarHBondContact O-N 3.02Å; L143-I147 VanDerWaalsContact O-N 3.07Å; L143-F395 HydrophobicContact CB-CE1 3.95Å; L143-F395 HydrophobicContact CB-CZ 4.35Å; L143-F395 HydrophobicContact CD2-CE1 3.75Å; L143-F395 HydrophobicContact CD2-CZ 3.84Å; L143-F395 HydrophobicContact CG-CE1 3.78Å; L143-F395 HydrophobicContact CG-CZ 3.75Å; L143-F446 HydrophobicContact CD1-CB 3.58Å; L143-F446 HydrophobicContact CD1-CD1 4Å; L143-F446 HydrophobicContact CD1-CG 4.12Å; L143-F446 WeakPolarHBondContact CD1-O 3.38Å; L143-P450 HydrophobicContact CD2-CG 3.96Å; L143-F515 HydrophobicContact CB-CZ 4.12Å; L143-F515 HydrophobicContact CD1-CE1 4.48Å; L143-L519 HydrophobicContact CD1-CD1 4.26Å
144	W	94.7	Very high	92	Very high	51 Å²	51	41.3 Å²	41.3	19%	0.193	22%	0.219	C	C	.	.	H	α-helix	trans	-56.1	-49.2	173.4	169.9	66.2	0	0	0	111.9	R140 I141 M146 I147 E148 M392 F395 L396	R140-W144 WeakPolarHBondContact O-CB 3.44Å; R140-W144 PolarHBondContact O-N 2.71Å; I141-W144 HydrophobicContact CG2-CE3 4.5Å; I141-W144 PolarHBondContact O-N 3.1Å; W144-M146 VanDerWaalsContact C-N 3.29Å; W144-M146 PolarHBondContact O-N 3.3Å; W144-I147 PolarHBondContact O-N 3.22Å; W144-E148 HydrophobicContact CZ2-CG 4.23Å; W144-E148 PolarHBondContact NE1-OE2 3Å; W144-E148 WeakPolarHBondContact O-CB 3.41Å; W144-E148 PolarHBondContact O-N 3.11Å; W144-M392 HydrophobicContact CZ2-CG 4.5Å; W144-F395 HydrophobicContact CB-CB 3.71Å; W144-F395 HydrophobicContact CB-CD1 4.01Å; W144-F395 HydrophobicContact CB-CD2 4.24Å; W144-F395 HydrophobicContact CB-CG 3.74Å; W144-F395 HydrophobicContact CG-CB 3.92Å; W144-F395 HydrophobicContact CG-CG 4.32Å; W144-L396 HydrophobicContact CD2-CD1 3.74Å; W144-L396 HydrophobicContact CD2-CD2 4.15Å; W144-L396 HydrophobicContact CD2-CG 4.05Å; W144-L396 VanDerWaalsContact CE2-CD1 3.5Å; W144-L396 HydrophobicContact CE3-CD1 4.11Å; W144-L396 HydrophobicContact CE3-CD2 4.3Å; W144-L396 HydrophobicContact CG-CD1 4.34Å; W144-L396 HydrophobicContact CG-CD2 4.29Å; W144-L396 HydrophobicContact CG-CG 4.17Å; W144-L396 HydrophobicContact CH2-CD1 3.99Å; W144-L396 HydrophobicContact CZ2-CD1 3.64Å; W144-L396 HydrophobicContact CZ3-CD1 4.21Å
145	L	94	Very high	92	Very high	94 Å²	94	38.2 Å²	38.2	49%	0.492	20%	0.204	S	C	.	.	H	α-helix	trans	-58.3	-41.9	180	-174.5	74.6	0	0	0	112	I141 L142 L143 E148 L149	I141-L145 PolarHBondContact O-N 3.41Å; L142-L145 PolarHBondContact O-N 3.5Å; L143-L145 PolarHBondContact O-N 3.37Å; L145-E148 PolarHBondContact O-N 3.4Å; L145-L149 WeakPolarHBondContact O-CB 3.22Å; L145-L149 PolarHBondContact O-N 3.14Å
146	M	94.2	Very high	92	Very high	41 Å²	41	38.6 Å²	38.6	20%	0.202	21%	0.207	C	C	.	.	H	α-helix	trans	-64.7	-43.6	178.6	-71.7	-59.2	166.7	0	0	112.2	L142 L143 W144 L149 A150 Q443 F446	L142-M146 WeakPolarHBondContact O-CG 3.11Å; L142-M146 PolarHBondContact O-N 2.76Å; L142-M146 VanDerWaalsContact O-N 3.1Å; L143-M146 PolarHBondContact O-N 2.92Å; W144-M146 VanDerWaalsContact C-N 3.29Å; W144-M146 PolarHBondContact O-N 3.3Å; M146-L149 PolarHBondContact O-N 3.28Å; M146-A150 PolarHBondContact O-N 3.47Å; M146-Q443 VanDerWaalsContact CB-OE1 3.28Å; M146-Q443 PolarHBondContact O-OE1 3.5Å; M146-Q443 VanDerWaalsContact O-OE1 3.11Å; M146-F446 HydrophobicContact CB-CB 4.43Å; M146-F446 HydrophobicContact CB-CD2 3.62Å; M146-F446 HydrophobicContact CB-CE2 3.98Å; M146-F446 HydrophobicContact CB-CG 3.99Å; M146-F446 HydrophobicContact CG-CD2 3.85Å; M146-F446 HydrophobicContact CG-CE1 4.46Å; M146-F446 HydrophobicContact CG-CE2 3.66Å; M146-F446 HydrophobicContact CG-CG 4.3Å; M146-F446 HydrophobicContact CG-CZ 4.01Å; M146-F446 HydrophobicContact SD-CD2 4.39Å; M146-F446 HydrophobicContact SD-CE2 3.78Å; M146-F446 HydrophobicContact SD-CZ 4.27Å
147	I	93.8	Very high	92	Very high	0 Å²	0	35 Å²	35	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-71.2	-37.9	177.7	-58.8	-54.8	0	0	0	111.6	L143 W144 L149 A150 I151 P260 Y264 V391 F446	L143-I147 WeakPolarHBondContact O-CG1 3.12Å; L143-I147 PolarHBondContact O-N 3.02Å; L143-I147 VanDerWaalsContact O-N 3.07Å; W144-I147 PolarHBondContact O-N 3.22Å; I147-L149 VanDerWaalsContact C-N 3.31Å; I147-L149 PolarHBondContact O-N 3.14Å; I147-A150 WeakPolarHBondContact O-CB 3.36Å; I147-A150 PolarHBondContact O-N 3.12Å; I147-A150 VanDerWaalsContact O-N 3.16Å; I147-I151 HydrophobicContact CG2-CD1 4.14Å; I147-I151 WeakPolarHBondContact O-CG1 3.16Å; I147-I151 PolarHBondContact O-N 3.31Å; I147-P260 HydrophobicContact CD1-CB 4.32Å; I147-Y264 HydrophobicContact CD1-CD2 4.28Å; I147-Y264 HydrophobicContact CD1-CE2 3.45Å; I147-Y264 VanDerWaalsContact CD1-CE2 3.45Å; I147-Y264 HydrophobicContact CG1-CD2 4.4Å; I147-Y264 HydrophobicContact CG1-CE2 3.64Å; I147-Y264 HydrophobicContact CG2-CD2 4Å; I147-Y264 HydrophobicContact CG2-CE2 4.09Å; I147-Y264 HydrophobicContact CG2-CG 4.49Å; I147-V391 HydrophobicContact CB-CG1 4.16Å; I147-V391 HydrophobicContact CG2-CB 4.35Å; I147-V391 HydrophobicContact CG2-CG1 3.78Å; I147-V391 HydrophobicContact CG2-CG2 3.62Å; I147-F446 HydrophobicContact CD1-CB 3.89Å
148	E	92.3	Very high	92	Very high	15 Å²	15	31.3 Å²	31.3	7%	0.07	16%	0.161	C	C	.	.	H	α-helix	trans	-62.6	-40.3	174.7	-160.2	69.6	-154.6	0	0	111	W144 L145 A150 I151 I152 M392	W144-E148 HydrophobicContact CZ2-CG 4.23Å; W144-E148 PolarHBondContact NE1-OE2 3Å; W144-E148 WeakPolarHBondContact O-CB 3.41Å; W144-E148 PolarHBondContact O-N 3.11Å; L145-E148 PolarHBondContact O-N 3.4Å; E148-A150 VanDerWaalsContact C-N 3.32Å; E148-A150 PolarHBondContact O-N 3.24Å; E148-I151 PolarHBondContact O-N 2.93Å; E148-I152 HydrophobicContact CG-CD1 4.3Å; E148-I152 WeakPolarHBondContact O-CG1 3.44Å; E148-I152 PolarHBondContact O-N 3.32Å; E148-M392 WeakPolarHBondContact OE2-CG 3.38Å
149	L	91.8	Very high	92	Very high	73 Å²	73	26.3 Å²	26.3	38%	0.382	13%	0.131	S	C	.	.	H	α-helix	trans	-61.5	-39.7	173.2	-175.7	66.3	0	0	0	111.9	L145 M146 I147 G153 L439	L145-L149 WeakPolarHBondContact O-CB 3.22Å; L145-L149 PolarHBondContact O-N 3.14Å; M146-L149 PolarHBondContact O-N 3.28Å; I147-L149 VanDerWaalsContact C-N 3.31Å; I147-L149 PolarHBondContact O-N 3.14Å; L149-G153 PolarHBondContact O-N 2.89Å; L149-L439 HydrophobicContact CD2-CD1 4.41Å; L149-L439 HydrophobicContact CG-CD1 4.43Å; L149-L439 HydrophobicContact CG-CD2 4.48Å
150	A	92.1	Very high	91.9	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-62.8	-41.4	174.2	0	0	0	0	0	111.9	M146 I147 E148 G153 S154 P260 Q440 Q443	M146-A150 PolarHBondContact O-N 3.47Å; I147-A150 WeakPolarHBondContact O-CB 3.36Å; I147-A150 PolarHBondContact O-N 3.12Å; I147-A150 VanDerWaalsContact O-N 3.16Å; E148-A150 VanDerWaalsContact C-N 3.32Å; E148-A150 PolarHBondContact O-N 3.24Å; A150-G153 PolarHBondContact O-N 3.39Å; A150-S154 PolarHBondContact O-N 2.83Å; A150-P260 HydrophobicContact CB-CG 4.38Å; A150-Q440 PolarHBondContact O-NE2 3.04Å; A150-Q440 PolarHBondContact O-OE1 3.29Å; A150-Q443 HydrophobicContact CB-CB 3.88Å; A150-Q443 HydrophobicContact CB-CG 3.89Å
151	I	91.4	Very high	91.8	Very high	3 Å²	3	23.1 Å²	23.1	2%	0.015	12%	0.116	C	C	.	.	H	α-helix	trans	-65.5	-47.7	177.8	-66.4	155.8	0	0	0	110.7	I147 E148 G153 S154 D155 H261 V391	I147-I151 HydrophobicContact CG2-CD1 4.14Å; I147-I151 WeakPolarHBondContact O-CG1 3.16Å; I147-I151 PolarHBondContact O-N 3.31Å; E148-I151 PolarHBondContact O-N 2.93Å; I151-G153 VanDerWaalsContact C-N 3.27Å; I151-G153 PolarHBondContact O-N 3.46Å; I151-S154 PolarHBondContact O-N 2.9Å; I151-D155 VanDerWaalsContact O-CB 3.28Å; I151-D155 WeakPolarHBondContact O-CB 3.49Å; I151-D155 PolarHBondContact O-N 2.89Å; I151-H261 HydrophobicContact CD1-CB 4.41Å; I151-H261 HydrophobicContact CG1-CB 3.57Å; I151-V391 HydrophobicContact CD1-CB 4.05Å; I151-V391 HydrophobicContact CD1-CG1 4.19Å; I151-V391 HydrophobicContact CD1-CG2 4Å
152	I	90.4	Very high	91.8	Very high	29 Å²	29	19.5 Å²	19.5	15%	0.149	10%	0.098	C	C	.	.	H	α-helix	trans	-60.1	-40.8	176.8	-67.1	162.2	0	0	0	110.5	E148 D155 M156 I412 A413	E148-I152 HydrophobicContact CG-CD1 4.3Å; E148-I152 WeakPolarHBondContact O-CG1 3.44Å; E148-I152 PolarHBondContact O-N 3.32Å; I152-D155 WeakPolarHBondContact O-CB 3.03Å; I152-D155 PolarHBondContact O-N 2.87Å; I152-M156 HydrophobicContact CG2-SD 4.43Å; I152-M156 WeakPolarHBondContact O-CG 3.31Å; I152-M156 PolarHBondContact O-N 2.97Å; I152-I412 HydrophobicContact CD1-CG2 3.84Å; I152-I412 HydrophobicContact CG1-CG2 4.34Å; I152-I412 HydrophobicContact CG2-CG2 4.19Å; I152-A413 HydrophobicContact CG2-CB 4.34Å
153	G	90	Very high	91.6	Very high	3 Å²	3	16.1 Å²	16.1	3%	0.031	8%	0.08	C	C	.	.	H	α-helix	trans	-61	-45.3	177	0	0	0	0	0	112.5	L149 A150 I151 M156 Q157	L149-G153 PolarHBondContact O-N 2.89Å; A150-G153 PolarHBondContact O-N 3.39Å; I151-G153 VanDerWaalsContact C-N 3.27Å; I151-G153 PolarHBondContact O-N 3.46Å; G153-M156 WeakPolarHBondContact O-CB 3.21Å; G153-M156 PolarHBondContact O-N 3.25Å; G153-Q157 WeakPolarHBondContact O-CG 3.22Å; G153-Q157 PolarHBondContact O-N 3.34Å
154	S	89.8	Confident	91.5	Very high	1 Å²	1	16.2 Å²	16.2	1%	0.007	8%	0.081	C	C	.	.	H	α-helix	trans	-65.6	-44.8	177.1	175.3	0	0	0	0	111.1	A150 I151 M156 Q157 E158 M259 H261 Q440	A150-S154 PolarHBondContact O-N 2.83Å; I151-S154 PolarHBondContact O-N 2.9Å; S154-M156 VanDerWaalsContact C-N 3.29Å; S154-M156 PolarHBondContact O-N 3.1Å; S154-Q157 WeakPolarHBondContact O-CA 3.3Å; S154-Q157 WeakPolarHBondContact O-CB 3.29Å; S154-Q157 PolarHBondContact O-N 3.35Å; S154-E158 WeakPolarHBondContact O-CG 3.23Å; S154-E158 PolarHBondContact O-N 2.97Å; S154-E158 VanDerWaalsContact O-N 3.12Å; S154-M259 WeakPolarHBondContact OG-CE 3.32Å; S154-H261 PolarHBondContact OG-CE1 2.91Å; S154-Q440 VanDerWaalsContact N-NE2 3.18Å
155	D	90.1	Very high	91.4	Very high	1 Å²	1	13.8 Å²	13.8	1%	0.005	7%	0.072	C	C	.	.	H	α-helix	trans	-51.8	-44.7	173.9	-173.9	-18.9	0	0	0	112.3	I151 I152 Q157 E158 V159 R410 A413	I151-D155 VanDerWaalsContact O-CB 3.28Å; I151-D155 WeakPolarHBondContact O-CB 3.49Å; I151-D155 PolarHBondContact O-N 2.89Å; I152-D155 WeakPolarHBondContact O-CB 3.03Å; I152-D155 PolarHBondContact O-N 2.87Å; D155-Q157 VanDerWaalsContact C-N 3.34Å; D155-Q157 PolarHBondContact O-N 3.43Å; D155-E158 WeakPolarHBondContact O-CB 3.25Å; D155-E158 PolarHBondContact O-N 3.48Å; D155-V159 WeakPolarHBondContact O-CG2 3.48Å; D155-V159 PolarHBondContact O-N 3.01Å; D155-V159 VanDerWaalsContact O-N 3.07Å; D155-R410 IonicContact OD1-CZ 3.02Å; D155-R410 IonicContact OD1-NE 3.43Å; D155-R410 PolarHBondContact OD1-NE 3.49Å; D155-R410 VanDerWaalsContact OD1-NE 3.08Å; D155-R410 IonicContact OD1-NH1 3.58Å; D155-R410 PolarHBondContact OD1-NH1 2.82Å; D155-R410 IonicContact OD1-NH2 2.86Å; D155-R410 PolarHBondContact OD1-NH2 3.3Å; D155-R410 VanDerWaalsContact OD1-NH2 3.07Å; D155-R410 IonicContact OD2-CZ 3.27Å; D155-R410 IonicContact OD2-NE 3.98Å; D155-R410 PolarHBondContact OD2-NE 2.76Å; D155-R410 IonicContact OD2-NH1 3.8Å; D155-R410 IonicContact OD2-NH2 2.83Å; D155-R410 PolarHBondContact OD2-NH2 2.93Å; D155-A413 HydrophobicContact CB-CB 3.75Å; D155-A413 VanDerWaalsContact OD1-CB 3.29Å; D155-A413 WeakPolarHBondContact OD1-CB 3.49Å; D155-A413 WeakPolarHBondContact OD2-CB 3.3Å
156	M	89.3	Confident	91.4	Very high	21 Å²	21	11.3 Å²	11.3	10%	0.103	6%	0.057	C	C	.	.	H	α-helix	trans	-59.1	-42.6	174.5	-71.8	175.9	65.5	0	0	112.5	I152 G153 S154 E158 V159 I160 A413 P416 M432 L436	I152-M156 HydrophobicContact CG2-SD 4.43Å; I152-M156 WeakPolarHBondContact O-CG 3.31Å; I152-M156 PolarHBondContact O-N 2.97Å; G153-M156 WeakPolarHBondContact O-CB 3.21Å; G153-M156 PolarHBondContact O-N 3.25Å; S154-M156 VanDerWaalsContact C-N 3.29Å; S154-M156 PolarHBondContact O-N 3.1Å; M156-E158 VanDerWaalsContact C-N 3.29Å; M156-E158 PolarHBondContact O-N 3.28Å; M156-V159 PolarHBondContact O-N 3.23Å; M156-I160 WeakPolarHBondContact O-CD1 3.42Å; M156-I160 WeakPolarHBondContact O-CG1 3.4Å; M156-I160 PolarHBondContact O-N 3.49Å; M156-A413 HydrophobicContact CG-CB 4.16Å; M156-P416 HydrophobicContact CE-CB 4.04Å; M156-P416 HydrophobicContact CE-CG 3.85Å; M156-P416 HydrophobicContact CG-CG 4.49Å; M156-P416 HydrophobicContact SD-CG 3.89Å; M156-M432 HydrophobicContact CE-CE 3.86Å; M156-M432 HydrophobicContact CE-CG 4.36Å; M156-M432 HydrophobicContact CE-SD 3.56Å; M156-M432 VanDerWaalsContact CE-SD 3.56Å; M156-L436 HydrophobicContact CB-CD1 3.67Å; M156-L436 HydrophobicContact CE-CD1 4.34Å; M156-L436 HydrophobicContact SD-CD2 4.27Å
157	Q	90.2	Very high	91.3	Very high	0 Å²	0	10.1 Å²	10.1	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-62.9	-37.5	178.8	-57.3	177.9	-73.5	0	0	111.5	G153 S154 D155 I160 G161 N433 L436 N437	G153-Q157 WeakPolarHBondContact O-CG 3.22Å; G153-Q157 PolarHBondContact O-N 3.34Å; S154-Q157 WeakPolarHBondContact O-CA 3.3Å; S154-Q157 WeakPolarHBondContact O-CB 3.29Å; S154-Q157 PolarHBondContact O-N 3.35Å; D155-Q157 VanDerWaalsContact C-N 3.34Å; D155-Q157 PolarHBondContact O-N 3.43Å; Q157-I160 PolarHBondContact O-N 3.26Å; Q157-G161 PolarHBondContact O-N 2.94Å; Q157-N433 WeakPolarHBondContact CG-OD1 3.39Å; Q157-N433 PolarHBondContact NE2-O 3.24Å; Q157-N433 PolarHBondContact NE2-OD1 2.99Å; Q157-L436 HydrophobicContact CG-CB 3.72Å; Q157-L436 HydrophobicContact CG-CD1 3.59Å; Q157-L436 HydrophobicContact CG-CG 4.28Å; Q157-N437 PolarHBondContact NE2-OD1 3.35Å
158	E	90.1	Very high	91.1	Very high	0 Å²	0	10.6 Å²	10.6	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-64.4	-46.7	176.7	-55.7	165.3	171.8	0	0	112	S154 D155 M156 I160 G161 C162 S380 T381 R410	S154-E158 WeakPolarHBondContact O-CG 3.23Å; S154-E158 PolarHBondContact O-N 2.97Å; S154-E158 VanDerWaalsContact O-N 3.12Å; D155-E158 WeakPolarHBondContact O-CB 3.25Å; D155-E158 PolarHBondContact O-N 3.48Å; M156-E158 VanDerWaalsContact C-N 3.29Å; M156-E158 PolarHBondContact O-N 3.28Å; E158-I160 VanDerWaalsContact C-N 3.32Å; E158-I160 PolarHBondContact O-N 3.37Å; E158-G161 PolarHBondContact O-N 3.38Å; E158-C162 WeakPolarHBondContact O-CB 3.21Å; E158-C162 PolarHBondContact O-N 3.05Å; E158-S380 VanDerWaalsContact CD-OG 3.29Å; E158-S380 WeakPolarHBondContact CG-OG 3.37Å; E158-S380 VanDerWaalsContact OE1-CB 3.32Å; E158-S380 WeakPolarHBondContact OE1-CB 3.29Å; E158-S380 PolarHBondContact OE1-OG 3Å; E158-T381 VanDerWaalsContact CD-N 3.29Å; E158-T381 PolarHBondContact OE1-N 3.4Å; E158-T381 WeakPolarHBondContact OE2-CA 3.36Å; E158-T381 PolarHBondContact OE2-N 2.95Å; E158-T381 PolarHBondContact OE2-OG1 3.27Å; E158-R410 IonicContact OE2-CZ 2.6Å; E158-R410 IonicContact OE2-NH1 2.98Å; E158-R410 PolarHBondContact OE2-NH1 3.15Å; E158-R410 IonicContact OE2-NH2 2.71Å; E158-R410 PolarHBondContact OE2-NH2 3.38Å
159	V	90.8	Very high	91.2	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-63.6	-41.8	180	173.4	0	0	0	0	110.2	D155 M156 A163 V180 T183 I414 T417	D155-V159 WeakPolarHBondContact O-CG2 3.48Å; D155-V159 PolarHBondContact O-N 3.01Å; D155-V159 VanDerWaalsContact O-N 3.07Å; M156-V159 PolarHBondContact O-N 3.23Å; V159-A163 VanDerWaalsContact O-CB 3.26Å; V159-A163 WeakPolarHBondContact O-CB 3.24Å; V159-A163 PolarHBondContact O-N 2.64Å; V159-V180 HydrophobicContact CG1-CB 4.21Å; V159-V180 HydrophobicContact CG1-CG1 3.72Å; V159-V180 HydrophobicContact CG1-CG2 4.04Å; V159-T183 HydrophobicContact CG1-CG2 4.44Å; V159-I414 HydrophobicContact CG1-CG1 4.38Å; V159-I414 HydrophobicContact CG2-CG1 4.03Å; V159-T417 HydrophobicContact CG1-CG2 3.91Å
160	I	89.7	Confident	91.1	Very high	4 Å²	4	10 Å²	10	2%	0.021	5%	0.053	C	C	.	.	H	α-helix	trans	-60.5	-50.4	173.8	-63.4	161	0	0	0	110.3	M156 Q157 E158 C162 A163 I164 T417 M432 L436	M156-I160 WeakPolarHBondContact O-CD1 3.42Å; M156-I160 WeakPolarHBondContact O-CG1 3.4Å; M156-I160 PolarHBondContact O-N 3.49Å; Q157-I160 PolarHBondContact O-N 3.26Å; E158-I160 VanDerWaalsContact C-N 3.32Å; E158-I160 PolarHBondContact O-N 3.37Å; I160-C162 PolarHBondContact O-N 2.8Å; I160-A163 PolarHBondContact O-N 2.89Å; I160-I164 HydrophobicContact CG2-CD1 3.68Å; I160-I164 HydrophobicContact CG2-CG1 4.41Å; I160-I164 WeakPolarHBondContact O-CB 3.45Å; I160-I164 VanDerWaalsContact O-CG1 3.3Å; I160-I164 WeakPolarHBondContact O-CG1 3.41Å; I160-I164 PolarHBondContact O-N 3.01Å; I160-T417 HydrophobicContact CG1-CG2 3.77Å; I160-M432 HydrophobicContact CD1-CE 3.27Å; I160-M432 HydrophobicContact CD1-CG 4.5Å; I160-M432 HydrophobicContact CG1-CE 3.77Å; I160-L436 HydrophobicContact CD1-CD1 4.23Å
161	G	91.8	Very high	90.8	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-59.3	-47	-179.5	0	0	0	0	0	113	Q157 E158 I164 A165 I373	Q157-G161 PolarHBondContact O-N 2.94Å; E158-G161 PolarHBondContact O-N 3.38Å; G161-I164 PolarHBondContact O-N 3.04Å; G161-A165 WeakPolarHBondContact O-CB 3.34Å; G161-A165 PolarHBondContact O-N 3.1Å; G161-I373 WeakPolarHBondContact O-CG2 3.44Å
162	C	92.4	Very high	90.4	Very high	0 Å²	0	15.8 Å²	15.8	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-61.9	-44.6	175.7	-77.8	0	0	0	0	112.2	E158 I160 I164 A165 F166 T183 G377 Q378	E158-C162 WeakPolarHBondContact O-CB 3.21Å; E158-C162 PolarHBondContact O-N 3.05Å; I160-C162 PolarHBondContact O-N 2.8Å; C162-I164 VanDerWaalsContact C-N 3.33Å; C162-I164 PolarHBondContact O-N 3.22Å; C162-A165 PolarHBondContact O-N 3.3Å; C162-F166 HydrophobicContact CB-CE2 4.45Å; C162-F166 WeakPolarHBondContact O-CD2 3.3Å; C162-F166 PolarHBondContact O-N 2.96Å; C162-T183 HydrophobicContact CB-CG2 3.53Å; C162-G377 VanDerWaalsContact SG-C 3.55Å; C162-G377 VanDerWaalsContact SG-CA 3.54Å; C162-Q378 PolarHBondContact SG-NE2 2.99Å; C162-Q378 VanDerWaalsContact SG-NE2 3.42Å
163	A	91.8	Very high	90.2	Very high	2 Å²	2	24.9 Å²	24.9	2%	0.017	13%	0.128	C	C	.	.	H	α-helix	trans	-62.4	-41.3	178.7	0	0	0	0	0	111.9	V159 I160 F166 N167 V180	V159-A163 VanDerWaalsContact O-CB 3.26Å; V159-A163 WeakPolarHBondContact O-CB 3.24Å; V159-A163 PolarHBondContact O-N 2.64Å; I160-A163 PolarHBondContact O-N 2.89Å; A163-F166 PolarHBondContact O-N 3.21Å; A163-N167 WeakPolarHBondContact O-CB 3.29Å; A163-N167 PolarHBondContact O-N 2.94Å; A163-V180 HydrophobicContact CB-CG2 3.66Å
164	I	90.4	Very high	90.3	Very high	3 Å²	3	27.2 Å²	27.2	2%	0.015	14%	0.139	C	C	.	.	H	α-helix	trans	-62.9	-45.2	174	-71.3	170.7	0	0	0	110.7	I160 G161 C162 F166 N167 L168 L176 I350 Y351	I160-I164 HydrophobicContact CG2-CD1 3.68Å; I160-I164 HydrophobicContact CG2-CG1 4.41Å; I160-I164 WeakPolarHBondContact O-CB 3.45Å; I160-I164 VanDerWaalsContact O-CG1 3.3Å; I160-I164 WeakPolarHBondContact O-CG1 3.41Å; I160-I164 PolarHBondContact O-N 3.01Å; G161-I164 PolarHBondContact O-N 3.04Å; C162-I164 VanDerWaalsContact C-N 3.33Å; C162-I164 PolarHBondContact O-N 3.22Å; I164-F166 PolarHBondContact O-N 2.92Å; I164-N167 WeakPolarHBondContact O-CB 3.37Å; I164-N167 PolarHBondContact O-N 3.03Å; I164-L168 HydrophobicContact CG2-CD1 3.98Å; I164-L168 HydrophobicContact CG2-CG 4.38Å; I164-L168 WeakPolarHBondContact O-CG 3.49Å; I164-L168 PolarHBondContact O-N 3.42Å; I164-L176 HydrophobicContact CG1-CD2 4.07Å; I164-I350 HydrophobicContact CD1-CB 4.5Å; I164-I350 HydrophobicContact CG2-CG2 3.79Å; I164-Y351 HydrophobicContact CG2-CD2 4.08Å; I164-Y351 HydrophobicContact CG2-CG 4.44Å
165	A	93.9	Very high	90.2	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-60.2	-44.7	177.6	0	0	0	0	0	112.1	G161 C162 N167 L168 L169 A370 I373 L374	G161-A165 WeakPolarHBondContact O-CB 3.34Å; G161-A165 PolarHBondContact O-N 3.1Å; C162-A165 PolarHBondContact O-N 3.3Å; A165-N167 VanDerWaalsContact C-N 3.32Å; A165-N167 PolarHBondContact O-N 2.68Å; A165-L168 PolarHBondContact O-N 3.14Å; A165-L169 WeakPolarHBondContact O-CB 3.48Å; A165-L169 VanDerWaalsContact O-CG 3.24Å; A165-L169 WeakPolarHBondContact O-CG 3.41Å; A165-L169 PolarHBondContact O-N 2.89Å; A165-A370 WeakPolarHBondContact CB-O 3.36Å; A165-I373 HydrophobicContact CB-CB 4.31Å; A165-I373 HydrophobicContact CB-CG2 4.08Å; A165-L374 HydrophobicContact CB-CB 3.86Å; A165-L374 HydrophobicContact CB-CD1 4.26Å
166	F	93.6	Very high	90.1	Very high	41 Å²	41	30.4 Å²	30.4	18%	0.18	16%	0.159	C	C	.	.	H	α-helix	trans	-62.3	-38.6	174.9	-72.1	-53.6	0	0	0	112.6	C162 A163 I164 S170 I182 L374	C162-F166 HydrophobicContact CB-CE2 4.45Å; C162-F166 WeakPolarHBondContact O-CD2 3.3Å; C162-F166 PolarHBondContact O-N 2.96Å; A163-F166 PolarHBondContact O-N 3.21Å; I164-F166 PolarHBondContact O-N 2.92Å; F166-S170 VanDerWaalsContact O-CB 3.22Å; F166-S170 WeakPolarHBondContact O-CB 3.42Å; F166-S170 PolarHBondContact O-N 3.27Å; F166-S170 PolarHBondContact O-OG 2.74Å; F166-I182 HydrophobicContact CD2-CB 4.44Å; F166-I182 HydrophobicContact CD2-CG2 4.18Å; F166-I182 HydrophobicContact CE1-CG2 4.32Å; F166-I182 HydrophobicContact CE2-CB 4.21Å; F166-I182 HydrophobicContact CE2-CG2 3.59Å; F166-I182 HydrophobicContact CZ-CG2 3.68Å; F166-L374 HydrophobicContact CD1-CD1 4.46Å; F166-L374 HydrophobicContact CE1-CD1 3.92Å; F166-L374 HydrophobicContact CE1-CD2 4.19Å; F166-L374 HydrophobicContact CE2-CD1 4.06Å; F166-L374 HydrophobicContact CZ-CD1 3.7Å
167	N	91.2	Very high	90.2	Very high	17 Å²	17	35.1 Å²	35.1	9%	0.091	18%	0.175	C	C	.	.	H	α-helix	trans	-63.9	-45.9	176	-174.2	-89.2	0	0	0	111.6	A163 I164 A165 S170 V171 G172 I174 L176 Y351	A163-N167 WeakPolarHBondContact O-CB 3.29Å; A163-N167 PolarHBondContact O-N 2.94Å; I164-N167 WeakPolarHBondContact O-CB 3.37Å; I164-N167 PolarHBondContact O-N 3.03Å; A165-N167 VanDerWaalsContact C-N 3.32Å; A165-N167 PolarHBondContact O-N 2.68Å; N167-S170 PolarHBondContact O-N 2.91Å; N167-S170 PolarHBondContact O-OG 3.36Å; N167-V171 PolarHBondContact O-N 3.44Å; N167-G172 PolarHBondContact O-N 3.02Å; N167-I174 PolarHBondContact ND2-O 3.13Å; N167-L176 HydrophobicContact CB-CD2 3.77Å; N167-Y351 VanDerWaalsContact OD1-CE2 3.24Å; N167-Y351 WeakPolarHBondContact OD1-CE2 3.49Å
168	L	90.5	Very high	90.2	Very high	9 Å²	9	36 Å²	36	5%	0.047	18%	0.183	C	C	.	.	H	α-helix	trans	-64.6	-48.5	177.6	-71	174.2	0	0	0	112.2	I164 A165 S170 V171 Y351 V355 L366 A370	I164-L168 HydrophobicContact CG2-CD1 3.98Å; I164-L168 HydrophobicContact CG2-CG 4.38Å; I164-L168 WeakPolarHBondContact O-CG 3.49Å; I164-L168 PolarHBondContact O-N 3.42Å; A165-L168 PolarHBondContact O-N 3.14Å; L168-S170 PolarHBondContact O-N 2.81Å; L168-V171 PolarHBondContact O-N 3.19Å; L168-V171 VanDerWaalsContact O-N 3.07Å; L168-Y351 HydrophobicContact CD1-CD2 4.46Å; L168-Y351 HydrophobicContact CD2-CD2 3.62Å; L168-Y351 HydrophobicContact CD2-CE2 3.55Å; L168-Y351 HydrophobicContact CG-CD2 3.9Å; L168-Y351 HydrophobicContact CG-CE2 4.14Å; L168-V355 HydrophobicContact CD2-CG2 4.05Å; L168-L366 HydrophobicContact CB-CD2 4.28Å; L168-A370 HydrophobicContact CB-CB 3.78Å; L168-A370 HydrophobicContact CD1-CB 4.3Å
169	L	93.3	Very high	90.3	Very high	55 Å²	55	36 Å²	36	29%	0.288	18%	0.183	S	C	.	.	H	α-helix	trans	-61.2	-33.4	179.3	-72.3	172.4	0	0	0	112.7	A165 V171 Y367 A370 V371 L374	A165-L169 WeakPolarHBondContact O-CB 3.48Å; A165-L169 VanDerWaalsContact O-CG 3.24Å; A165-L169 WeakPolarHBondContact O-CG 3.41Å; A165-L169 PolarHBondContact O-N 2.89Å; L169-V171 VanDerWaalsContact C-N 3.32Å; L169-Y367 HydrophobicContact CD2-CD1 4.17Å; L169-A370 HydrophobicContact CD2-CB 3.78Å; L169-A370 HydrophobicContact CG-CB 3.77Å; L169-V371 HydrophobicContact CD2-CG2 3.99Å; L169-L374 HydrophobicContact CD1-CD2 3.93Å
170	S	90.8	Very high	90.2	Very high	22 Å²	22	36 Å²	36	15%	0.154	18%	0.183	C	C	.	.	T	Hydrogen-bonded Turn	trans	-88.8	5.2	179.3	69.1	0	0	0	0	113.6	F166 N167 L168 G172 R173 I174	F166-S170 VanDerWaalsContact O-CB 3.22Å; F166-S170 WeakPolarHBondContact O-CB 3.42Å; F166-S170 PolarHBondContact O-N 3.27Å; F166-S170 PolarHBondContact O-OG 2.74Å; N167-S170 PolarHBondContact O-N 2.91Å; N167-S170 PolarHBondContact O-OG 3.36Å; L168-S170 PolarHBondContact O-N 2.81Å; S170-G172 PolarHBondContact O-N 2.64Å; S170-R173 VanDerWaalsContact O-CB 3.26Å; S170-R173 WeakPolarHBondContact O-CB 3.36Å; S170-R173 WeakPolarHBondContact O-CG 3.26Å; S170-R173 PolarHBondContact O-N 2.77Å; S170-R173 PolarHBondContact OG-N 3.45Å; S170-I174 WeakPolarHBondContact OG-CB 3.19Å; S170-I174 PolarHBondContact OG-N 2.99Å
171	V	84.9	Confident	90.3	Very high	89 Å²	89	39.2 Å²	39.2	54%	0.539	20%	0.2	S	C	.	.	T	Hydrogen-bonded Turn	trans	54.5	39.7	-176.4	-161.7	0	0	0	0	111.3	N167 L168 L169 R173 Y367	N167-V171 PolarHBondContact O-N 3.44Å; L168-V171 PolarHBondContact O-N 3.19Å; L168-V171 VanDerWaalsContact O-N 3.07Å; L169-V171 VanDerWaalsContact C-N 3.32Å; V171-R173 VanDerWaalsContact C-N 3.31Å; V171-R173 PolarHBondContact O-N 2.94Å; V171-Y367 HydrophobicContact CG2-CE1 4.28Å; V171-Y367 WeakPolarHBondContact CG2-OH 3.5Å
172	G	82.4	Confident	90.3	Very high	35 Å²	35	42.1 Å²	42.1	36%	0.361	22%	0.215	S	C	.	.	T	Hydrogen-bonded Turn	trans	75.6	9.4	-178.9	0	0	0	0	0	115.3	N167 S170	N167-G172 PolarHBondContact O-N 3.02Å; S170-G172 PolarHBondContact O-N 2.64Å
173	R	87.7	Confident	90.1	Very high	220 Å²	220	42.2 Å²	42.2	83%	0.83	22%	0.215	S	C	*	.	S	Bend	trans	-71	-33.6	175	-64.4	-67.5	-174.2	98.4	2.5	112.4	S170 V171 P175	S170-R173 VanDerWaalsContact O-CB 3.26Å; S170-R173 WeakPolarHBondContact O-CB 3.36Å; S170-R173 WeakPolarHBondContact O-CG 3.26Å; S170-R173 PolarHBondContact O-N 2.77Å; S170-R173 PolarHBondContact OG-N 3.45Å; V171-R173 VanDerWaalsContact C-N 3.31Å; V171-R173 PolarHBondContact O-N 2.94Å; R173-P175 WeakPolarHBondContact O-CD 3.49Å
174	I	90.8	Very high	89.9	Confident	51 Å²	51	45 Å²	45	26%	0.262	23%	0.229	S	C	.	.	S	Bend	trans	-95	110.2	173.7	-59.2	174.9	0	0	0	107.5	N167 S170 A178 I182	N167-I174 PolarHBondContact ND2-O 3.13Å; S170-I174 WeakPolarHBondContact OG-CB 3.19Å; S170-I174 PolarHBondContact OG-N 2.99Å; I174-A178 HydrophobicContact CG2-CB 3.94Å; I174-I182 HydrophobicContact CD1-CD1 4.27Å; I174-I182 HydrophobicContact CG2-CD1 3.96Å
175	P	89.6	Confident	89.6	Confident	51 Å²	51	48.8 Å²	48.8	33%	0.331	25%	0.253	S	S	.	.			trans	-67.5	158.3	176	29.4	-35	0	0	0	111	R173 W177 A178 G179	R173-P175 WeakPolarHBondContact O-CD 3.49Å; P175-W177 HydrophobicContact CG-CD2 4.37Å; P175-W177 HydrophobicContact CG-CZ2 3.94Å; P175-W177 VanDerWaalsContact CG-NE1 3.3Å; P175-W177 PolarHBondContact O-N 3.49Å; P175-A178 HydrophobicContact CG-CB 3.79Å; P175-A178 WeakPolarHBondContact O-CB 3.48Å; P175-A178 PolarHBondContact O-N 3.25Å; P175-G179 PolarHBondContact O-N 3.45Å
176	L	87.9	Confident	89.1	Confident	19 Å²	19	49.1 Å²	49.1	10%	0.099	25%	0.254	C	S	.	.	H	α-helix	trans	-57.1	-43.7	-174.5	-66.9	175.6	0	0	0	113.1	I164 N167 A178 G179 V180 V426 L429	I164-L176 HydrophobicContact CG1-CD2 4.07Å; N167-L176 HydrophobicContact CB-CD2 3.77Å; L176-A178 PolarHBondContact O-N 3.07Å; L176-G179 CarbonylContact O-C 3.18Å; L176-G179 WeakPolarHBondContact O-CA 3.47Å; L176-G179 PolarHBondContact O-N 3.35Å; L176-V180 WeakPolarHBondContact O-CG2 3.19Å; L176-V180 PolarHBondContact O-N 2.87Å; L176-V426 HydrophobicContact CD1-CB 4.2Å; L176-V426 HydrophobicContact CD1-CG1 4.05Å; L176-V426 HydrophobicContact CD1-CG2 3.69Å; L176-L429 HydrophobicContact CB-CD1 4.24Å; L176-L429 HydrophobicContact CD1-CD1 3.53Å; L176-L429 HydrophobicContact CG-CD1 4.47Å
177	W	89.9	Confident	88.3	Confident	119 Å²	119	47.3 Å²	47.3	45%	0.451	25%	0.246	S	C	.	.	H	α-helix	trans	-59.6	-35.5	177.1	68.2	-98.4	0	0	0	112.5	P175 V180 L181 L418 A421 I422	P175-W177 HydrophobicContact CG-CD2 4.37Å; P175-W177 HydrophobicContact CG-CZ2 3.94Å; P175-W177 VanDerWaalsContact CG-NE1 3.3Å; P175-W177 PolarHBondContact O-N 3.49Å; W177-V180 PolarHBondContact O-N 3.39Å; W177-L181 HydrophobicContact CE3-CD1 3.8Å; W177-L181 HydrophobicContact CZ3-CD1 3.8Å; W177-L181 WeakPolarHBondContact O-CG 3.43Å; W177-L181 PolarHBondContact O-N 3.32Å; W177-L181 VanDerWaalsContact O-N 3.11Å; W177-L418 HydrophobicContact CB-CD1 4.12Å; W177-A421 HydrophobicContact CB-CB 4.1Å; W177-I422 HydrophobicContact CB-CG1 3.92Å; W177-I422 HydrophobicContact CG-CG1 4.47Å
178	A	91	Very high	87.8	Confident	18 Å²	18	51.6 Å²	51.6	15%	0.149	26%	0.264	C	S	.	.	H	α-helix	trans	-72.7	-37.8	176	0	0	0	0	0	110.6	I174 P175 L176 V180 L181 I182	I174-A178 HydrophobicContact CG2-CB 3.94Å; P175-A178 HydrophobicContact CG-CB 3.79Å; P175-A178 WeakPolarHBondContact O-CB 3.48Å; P175-A178 PolarHBondContact O-N 3.25Å; L176-A178 PolarHBondContact O-N 3.07Å; A178-V180 VanDerWaalsContact C-N 3.33Å; A178-V180 PolarHBondContact O-N 2.89Å; A178-L181 PolarHBondContact O-N 3.46Å; A178-I182 VanDerWaalsContact O-CG1 3.26Å; A178-I182 WeakPolarHBondContact O-CG1 3.48Å; A178-I182 PolarHBondContact O-N 3.01Å
179	G	91	Very high	87.4	Confident	0 Å²	0	54.2 Å²	54.2	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-55.9	-46.4	170.3	0	0	0	0	0	112.2	P175 L176 L181 I182 T183	P175-G179 PolarHBondContact O-N 3.45Å; L176-G179 CarbonylContact O-C 3.18Å; L176-G179 WeakPolarHBondContact O-CA 3.47Å; L176-G179 PolarHBondContact O-N 3.35Å; G179-L181 VanDerWaalsContact C-N 3.32Å; G179-L181 PolarHBondContact O-N 2.95Å; G179-I182 WeakPolarHBondContact O-CB 3.4Å; G179-I182 PolarHBondContact O-N 3.46Å; G179-I182 VanDerWaalsContact O-N 3.16Å; G179-T183 WeakPolarHBondContact O-CG2 3.38Å; G179-T183 PolarHBondContact O-N 3.26Å
180	V	90.4	Very high	86.7	Confident	2 Å²	2	51.6 Å²	51.6	1%	0.012	27%	0.267	C	S	.	.	H	α-helix	trans	-61.1	-36.6	175.2	172.3	0	0	0	0	112.1	V159 A163 L176 W177 A178 T183 I414 T417 L418 A421	V159-V180 HydrophobicContact CG1-CB 4.21Å; V159-V180 HydrophobicContact CG1-CG1 3.72Å; V159-V180 HydrophobicContact CG1-CG2 4.04Å; A163-V180 HydrophobicContact CB-CG2 3.66Å; L176-V180 WeakPolarHBondContact O-CG2 3.19Å; L176-V180 PolarHBondContact O-N 2.87Å; W177-V180 PolarHBondContact O-N 3.39Å; A178-V180 VanDerWaalsContact C-N 3.33Å; A178-V180 PolarHBondContact O-N 2.89Å; V180-T183 PolarHBondContact O-OG1 3Å; V180-I414 HydrophobicContact CG1-CG2 3.8Å; V180-T417 HydrophobicContact CG1-CG2 4.46Å; V180-T417 HydrophobicContact CG2-CG2 3.98Å; V180-L418 HydrophobicContact CB-CD1 4.44Å; V180-L418 HydrophobicContact CG1-CB 4.06Å; V180-L418 HydrophobicContact CG1-CD1 4.17Å; V180-A421 HydrophobicContact CG2-CB 4.42Å
181	L	90.8	Very high	86	Confident	71 Å²	71	52.2 Å²	52.2	37%	0.372	27%	0.269	S	S	.	.	H	α-helix	trans	-72.8	-33.9	175.2	-69.3	176.2	0	0	0	112.4	W177 A178 G179 T183 I184 L418	W177-L181 HydrophobicContact CE3-CD1 3.8Å; W177-L181 HydrophobicContact CZ3-CD1 3.8Å; W177-L181 WeakPolarHBondContact O-CG 3.43Å; W177-L181 PolarHBondContact O-N 3.32Å; W177-L181 VanDerWaalsContact O-N 3.11Å; A178-L181 PolarHBondContact O-N 3.46Å; G179-L181 VanDerWaalsContact C-N 3.32Å; G179-L181 PolarHBondContact O-N 2.95Å; L181-T183 PolarHBondContact O-N 2.98Å; L181-I184 HydrophobicContact CD2-CD1 4.01Å; L181-I184 WeakPolarHBondContact O-CB 3.48Å; L181-I184 WeakPolarHBondContact O-CG1 3.4Å; L181-I184 PolarHBondContact O-N 3.33Å; L181-I184 VanDerWaalsContact O-N 3.16Å; L181-L418 HydrophobicContact CD2-CD1 4.19Å; L181-L418 HydrophobicContact CD2-CD2 3.97Å; L181-L418 HydrophobicContact CG-CD1 4.15Å
182	I	91.1	Very high	85.9	Confident	61 Å²	61	53.8 Å²	53.8	31%	0.313	27%	0.268	S	S	.	.	H	α-helix	trans	-63.3	-33	177.3	-70.3	163.3	0	0	0	110.7	F166 I174 A178 G179 I184 T185	F166-I182 HydrophobicContact CD2-CB 4.44Å; F166-I182 HydrophobicContact CD2-CG2 4.18Å; F166-I182 HydrophobicContact CE1-CG2 4.32Å; F166-I182 HydrophobicContact CE2-CB 4.21Å; F166-I182 HydrophobicContact CE2-CG2 3.59Å; F166-I182 HydrophobicContact CZ-CG2 3.68Å; I174-I182 HydrophobicContact CD1-CD1 4.27Å; I174-I182 HydrophobicContact CG2-CD1 3.96Å; A178-I182 VanDerWaalsContact O-CG1 3.26Å; A178-I182 WeakPolarHBondContact O-CG1 3.48Å; A178-I182 PolarHBondContact O-N 3.01Å; G179-I182 WeakPolarHBondContact O-CB 3.4Å; G179-I182 PolarHBondContact O-N 3.46Å; G179-I182 VanDerWaalsContact O-N 3.16Å; I182-I184 PolarHBondContact O-N 3.46Å; I182-T185 WeakPolarHBondContact O-CB 3.47Å; I182-T185 PolarHBondContact O-N 2.98Å; I182-T185 PolarHBondContact O-OG1 3Å
183	T	89.7	Confident	85.6	Confident	1 Å²	1	54 Å²	54	1%	0.006	26%	0.261	C	S	.	.	H	α-helix	trans	-60.7	-25.8	176.5	68.3	0	0	0	0	112.1	V159 C162 G179 V180 L181 T185 D186	V159-T183 HydrophobicContact CG1-CG2 4.44Å; C162-T183 HydrophobicContact CB-CG2 3.53Å; G179-T183 WeakPolarHBondContact O-CG2 3.38Å; G179-T183 PolarHBondContact O-N 3.26Å; V180-T183 PolarHBondContact O-OG1 3Å; L181-T183 PolarHBondContact O-N 2.98Å; T183-T185 PolarHBondContact O-N 3.45Å; T183-D186 WeakPolarHBondContact CA-OD2 3.4Å; T183-D186 WeakPolarHBondContact CB-OD2 3.33Å; T183-D186 WeakPolarHBondContact O-CB 3.32Å; T183-D186 PolarHBondContact O-N 3.26Å
184	I	86.5	Confident	84.9	Confident	62 Å²	62	44.6 Å²	44.6	32%	0.318	23%	0.227	S	C	.	.	H	α-helix	trans	-54.7	-28.6	171.9	-58.4	170	0	0	0	111.8	L181 I182 T187 F188 I414	L181-I184 HydrophobicContact CD2-CD1 4.01Å; L181-I184 WeakPolarHBondContact O-CB 3.48Å; L181-I184 WeakPolarHBondContact O-CG1 3.4Å; L181-I184 PolarHBondContact O-N 3.33Å; L181-I184 VanDerWaalsContact O-N 3.16Å; I182-I184 PolarHBondContact O-N 3.46Å; I184-T187 WeakPolarHBondContact O-CB 3.47Å; I184-T187 PolarHBondContact O-N 3.45Å; I184-F188 HydrophobicContact CG2-CE2 3.95Å; I184-F188 VanDerWaalsContact O-CD2 3.25Å; I184-F188 WeakPolarHBondContact O-CD2 3.42Å; I184-I414 HydrophobicContact CG1-CD1 3.64Å
185	T	84.9	Confident	84.3	Confident	82 Å²	82	50.8 Å²	50.8	50%	0.503	25%	0.252	S	S	.	.	H	α-helix	trans	-65.9	-35.6	175.3	-44.7	0	0	0	0	112.7	I182 T183 T187 F188 V189	I182-T185 WeakPolarHBondContact O-CB 3.47Å; I182-T185 PolarHBondContact O-N 2.98Å; I182-T185 PolarHBondContact O-OG1 3Å; T183-T185 PolarHBondContact O-N 3.45Å; T185-T187 PolarHBondContact O-N 3.13Å; T185-F188 WeakPolarHBondContact O-CB 3.23Å; T185-F188 PolarHBondContact O-N 2.78Å; T185-F188 VanDerWaalsContact O-N 3.12Å; T185-V189 WeakPolarHBondContact O-CG2 3.36Å; T185-V189 PolarHBondContact O-N 3.39Å
186	D	82.2	Confident	83.7	Confident	7 Å²	7	53.8 Å²	53.8	4%	0.037	26%	0.258	C	S	.	.	H	α-helix	trans	-60.5	-31.8	178.6	66.1	31.7	0	0	0	112.2	T183 F188 V189 F190 Q378 T381	T183-D186 WeakPolarHBondContact CA-OD2 3.4Å; T183-D186 WeakPolarHBondContact CB-OD2 3.33Å; T183-D186 WeakPolarHBondContact O-CB 3.32Å; T183-D186 PolarHBondContact O-N 3.26Å; D186-F188 VanDerWaalsContact C-N 3.33Å; D186-F188 PolarHBondContact O-N 3.38Å; D186-V189 WeakPolarHBondContact O-CB 3.42Å; D186-V189 PolarHBondContact O-N 2.9Å; D186-F190 WeakPolarHBondContact O-CB 3Å; D186-F190 PolarHBondContact O-N 3.33Å; D186-Q378 PolarHBondContact OD2-NE2 3.47Å; D186-T381 WeakPolarHBondContact OD1-CG2 3.27Å
187	T	77.8	Confident	83.3	Confident	2 Å²	2	54.6 Å²	54.6	1%	0.012	27%	0.271	C	S	.	.	H	α-helix	trans	-67.6	-40.1	-180	-61.3	0	0	0	0	110.1	I184 T185 L191 V406 R410	I184-T187 WeakPolarHBondContact O-CB 3.47Å; I184-T187 PolarHBondContact O-N 3.45Å; T185-T187 PolarHBondContact O-N 3.13Å; T187-L191 HydrophobicContact CG2-CD1 4.4Å; T187-L191 WeakPolarHBondContact O-CD1 3.32Å; T187-L191 VanDerWaalsContact O-CG 3.25Å; T187-L191 WeakPolarHBondContact O-CG 3.4Å; T187-L191 PolarHBondContact O-N 2.93Å; T187-L191 VanDerWaalsContact O-N 3.08Å; T187-V406 HydrophobicContact CG2-CG1 3.25Å; T187-R410 HydrophobicContact CG2-CG 4.18Å
188	F	81.1	Confident	82.9	Confident	107 Å²	107	50.2 Å²	50.2	47%	0.469	26%	0.256	S	S	.	.	H	α-helix	trans	-68.7	-38.8	172.5	-66.8	-70	0	0	0	112.2	I184 T185 D186 F190 L191 F192 F403	I184-F188 HydrophobicContact CG2-CE2 3.95Å; I184-F188 VanDerWaalsContact O-CD2 3.25Å; I184-F188 WeakPolarHBondContact O-CD2 3.42Å; T185-F188 WeakPolarHBondContact O-CB 3.23Å; T185-F188 PolarHBondContact O-N 2.78Å; T185-F188 VanDerWaalsContact O-N 3.12Å; D186-F188 VanDerWaalsContact C-N 3.33Å; D186-F188 PolarHBondContact O-N 3.38Å; F188-F190 VanDerWaalsContact C-N 3.34Å; F188-L191 PolarHBondContact O-N 3.42Å; F188-F192 WeakPolarHBondContact O-CB 3.38Å; F188-F192 PolarHBondContact O-N 3.43Å; F188-F403 HydrophobicContact CD1-CE2 4.3Å; F188-F403 AromaticContact CE1-CE2 3.89Å; F188-F403 HydrophobicContact CE1-CE2 3.89Å; F188-F403 AromaticContact CE1-CZ 3.98Å; F188-F403 HydrophobicContact CE1-CZ 3.98Å
189	V	81.1	Confident	82.6	Confident	64 Å²	64	53.5 Å²	53.5	39%	0.388	27%	0.265	S	S	.	.	H	α-helix	trans	-61.8	-44	175.5	172.9	0	0	0	0	110.6	T185 D186 F192 L193	T185-V189 WeakPolarHBondContact O-CG2 3.36Å; T185-V189 PolarHBondContact O-N 3.39Å; D186-V189 WeakPolarHBondContact O-CB 3.42Å; D186-V189 PolarHBondContact O-N 2.9Å; V189-F192 WeakPolarHBondContact O-CB 3.46Å; V189-F192 PolarHBondContact O-N 3.39Å; V189-L193 HydrophobicContact CG1-CD1 3.88Å; V189-L193 HydrophobicContact CG1-CG 4.36Å; V189-L193 WeakPolarHBondContact O-CB 3.44Å; V189-L193 WeakPolarHBondContact O-CG 3.11Å; V189-L193 PolarHBondContact O-N 3.47Å
190	F	78.4	Confident	82.4	Confident	0 Å²	0	60.1 Å²	60.1	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-59.6	-52.3	175.8	170.6	-111.5	0	0	0	111.8	Y44 D186 F188 F192 L193 D194 M382 T385 Y386	Y44-F190 HydrophobicContact CE1-CZ 4.48Å; D186-F190 WeakPolarHBondContact O-CB 3Å; D186-F190 PolarHBondContact O-N 3.33Å; F188-F190 VanDerWaalsContact C-N 3.34Å; F190-F192 PolarHBondContact O-N 3.39Å; F190-L193 PolarHBondContact O-N 3.25Å; F190-D194 WeakPolarHBondContact O-CB 3.46Å; F190-D194 PolarHBondContact O-N 3.34Å; F190-M382 HydrophobicContact CB-CE 4.2Å; F190-M382 HydrophobicContact CB-CG 4.15Å; F190-M382 HydrophobicContact CD2-CB 3.67Å; F190-M382 HydrophobicContact CD2-CE 4.37Å; F190-M382 HydrophobicContact CD2-CG 3.41Å; F190-M382 VanDerWaalsContact CD2-CG 3.41Å; F190-M382 HydrophobicContact CD2-SD 3.77Å; F190-M382 HydrophobicContact CE2-CB 3.86Å; F190-M382 HydrophobicContact CE2-CG 4.13Å; F190-M382 HydrophobicContact CG-CB 4.46Å; F190-M382 HydrophobicContact CG-CG 4.02Å; F190-T385 WeakPolarHBondContact CE1-OG1 3.5Å; F190-T385 WeakPolarHBondContact CZ-OG1 3.37Å; F190-Y386 HydrophobicContact CE2-CD2 4.24Å; F190-Y386 AromaticContact CE2-CE2 3.43Å; F190-Y386 HydrophobicContact CE2-CE2 3.43Å; F190-Y386 VanDerWaalsContact CE2-CE2 3.43Å; F190-Y386 AromaticContact CE2-CZ 3.67Å; F190-Y386 HydrophobicContact CZ-CD2 4.18Å; F190-Y386 HydrophobicContact CZ-CE1 4.23Å; F190-Y386 AromaticContact CZ-CE2 3.62Å; F190-Y386 HydrophobicContact CZ-CE2 3.62Å; F190-Y386 AromaticContact CZ-CZ 3.6Å
191	L	77.3	Confident	82.1	Confident	36 Å²	36	60.2 Å²	60.2	19%	0.188	29%	0.294	C	S	.	.	H	α-helix	trans	-58.6	-33.7	178.9	-71.9	164.3	0	0	0	112.4	T187 F188 F403	T187-L191 HydrophobicContact CG2-CD1 4.4Å; T187-L191 WeakPolarHBondContact O-CD1 3.32Å; T187-L191 VanDerWaalsContact O-CG 3.25Å; T187-L191 WeakPolarHBondContact O-CG 3.4Å; T187-L191 PolarHBondContact O-N 2.93Å; T187-L191 VanDerWaalsContact O-N 3.08Å; F188-L191 PolarHBondContact O-N 3.42Å; L191-F403 HydrophobicContact CD1-CD2 3.44Å; L191-F403 VanDerWaalsContact CD1-CD2 3.44Å; L191-F403 HydrophobicContact CD1-CE2 3.72Å
192	F	81.3	Confident	81.9	Confident	121 Å²	121	57.6 Å²	57.6	53%	0.531	28%	0.28	S	S	.	.	H	α-helix	trans	-70.6	-45.8	174.3	-178.8	-103.9	0	0	0	112	F188 V189 F190 D194 K195 Y196	F188-F192 WeakPolarHBondContact O-CB 3.38Å; F188-F192 PolarHBondContact O-N 3.43Å; V189-F192 WeakPolarHBondContact O-CB 3.46Å; V189-F192 PolarHBondContact O-N 3.39Å; F190-F192 PolarHBondContact O-N 3.39Å; F192-D194 VanDerWaalsContact C-N 3.34Å; F192-D194 PolarHBondContact O-N 3.08Å; F192-K195 WeakPolarHBondContact O-CB 3.44Å; F192-K195 PolarHBondContact O-N 3.48Å; F192-Y196 HydrophobicContact CD1-CD2 4.48Å; F192-Y196 AromaticContact CD1-CE2 3.75Å; F192-Y196 HydrophobicContact CD1-CE2 3.75Å; F192-Y196 HydrophobicContact CD2-CE2 4.3Å; F192-Y196 HydrophobicContact CE1-CD2 4.4Å; F192-Y196 AromaticContact CE1-CE2 3.36Å; F192-Y196 HydrophobicContact CE1-CE2 3.36Å; F192-Y196 AromaticContact CE1-CZ 3.89Å; F192-Y196 AromaticContact CE2-CE2 3.96Å; F192-Y196 HydrophobicContact CE2-CE2 3.96Å; F192-Y196 HydrophobicContact CG-CE2 4.22Å; F192-Y196 AromaticContact CZ-CE2 3.49Å; F192-Y196 HydrophobicContact CZ-CE2 3.49Å; F192-Y196 VanDerWaalsContact CZ-CE2 3.49Å; F192-Y196 AromaticContact CZ-CZ 3.67Å; F192-Y196 WeakPolarHBondContact CZ-OH 3.36Å; F192-Y196 WeakPolarHBondContact O-CD2 3.22Å; F192-Y196 WeakPolarHBondContact O-CE2 3.28Å
193	L	77.5	Confident	81.9	Confident	41 Å²	41	58 Å²	58	22%	0.215	29%	0.292	C	S	.	.	H	α-helix	trans	-64.7	-36.7	179.4	-75.7	172.9	0	0	0	112.8	V189 F190 K195 Y196 L201 F204 M382	V189-L193 HydrophobicContact CG1-CD1 3.88Å; V189-L193 HydrophobicContact CG1-CG 4.36Å; V189-L193 WeakPolarHBondContact O-CB 3.44Å; V189-L193 WeakPolarHBondContact O-CG 3.11Å; V189-L193 PolarHBondContact O-N 3.47Å; F190-L193 PolarHBondContact O-N 3.25Å; L193-K195 PolarHBondContact O-N 3.42Å; L193-Y196 WeakPolarHBondContact O-CB 3.43Å; L193-Y196 PolarHBondContact O-N 3.18Å; L193-L201 HydrophobicContact CB-CD1 4.28Å; L193-F204 HydrophobicContact CD1-CD1 4.01Å; L193-F204 HydrophobicContact CD1-CE1 3.86Å; L193-F204 HydrophobicContact CD1-CE2 4.42Å; L193-F204 HydrophobicContact CD1-CG 4.36Å; L193-F204 HydrophobicContact CD1-CZ 4.07Å; L193-M382 HydrophobicContact CD1-CE 3.86Å
194	D	72.4	Confident	81.9	Confident	22 Å²	22	60.8 Å²	60.8	12%	0.118	30%	0.304	C	S	.	.	H	α-helix	trans	-57.7	-31.4	177.7	-174.5	55.6	0	0	0	112.6	Y44 F190 F192 Y196 Y386 R402	Y44-D194 WeakPolarHBondContact CD1-OD1 3.47Å; Y44-D194 WeakPolarHBondContact CD1-OD2 3.48Å; Y44-D194 HydrophobicContact CE1-CB 4.47Å; Y44-D194 WeakPolarHBondContact CE1-OD1 3.33Å; Y44-D194 WeakPolarHBondContact CE1-OD2 3.4Å; F190-D194 WeakPolarHBondContact O-CB 3.46Å; F190-D194 PolarHBondContact O-N 3.34Å; F192-D194 VanDerWaalsContact C-N 3.34Å; F192-D194 PolarHBondContact O-N 3.08Å; D194-Y196 PolarHBondContact O-N 3.12Å; D194-Y386 PolarHBondContact OD1-OH 3.05Å; D194-R402 IonicContact OD2-CZ 3.32Å; D194-R402 IonicContact OD2-NH1 3.57Å; D194-R402 PolarHBondContact OD2-NH1 2.95Å
195	K	78.1	Confident	82	Confident	181 Å²	181	57.9 Å²	57.9	79%	0.787	29%	0.289	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.8	-19.2	177.2	-166.9	175.6	178.6	-179.1	0	113.7	F192 L193	F192-K195 WeakPolarHBondContact O-CB 3.44Å; F192-K195 PolarHBondContact O-N 3.48Å; L193-K195 PolarHBondContact O-N 3.42Å
196	Y	77.6	Confident	82.3	Confident	113 Å²	113	55.2 Å²	55.2	44%	0.443	28%	0.278	S	S	.	.	T	Hydrogen-bonded Turn	trans	-87.7	0.2	-173.7	-74.8	-83.9	0	0	0	114.7	F192 L193 D194	F192-Y196 HydrophobicContact CD1-CD2 4.48Å; F192-Y196 AromaticContact CD1-CE2 3.75Å; F192-Y196 HydrophobicContact CD1-CE2 3.75Å; F192-Y196 HydrophobicContact CD2-CE2 4.3Å; F192-Y196 HydrophobicContact CE1-CD2 4.4Å; F192-Y196 AromaticContact CE1-CE2 3.36Å; F192-Y196 HydrophobicContact CE1-CE2 3.36Å; F192-Y196 AromaticContact CE1-CZ 3.89Å; F192-Y196 AromaticContact CE2-CE2 3.96Å; F192-Y196 HydrophobicContact CE2-CE2 3.96Å; F192-Y196 HydrophobicContact CG-CE2 4.22Å; F192-Y196 AromaticContact CZ-CE2 3.49Å; F192-Y196 HydrophobicContact CZ-CE2 3.49Å; F192-Y196 VanDerWaalsContact CZ-CE2 3.49Å; F192-Y196 AromaticContact CZ-CZ 3.67Å; F192-Y196 WeakPolarHBondContact CZ-OH 3.36Å; F192-Y196 WeakPolarHBondContact O-CD2 3.22Å; F192-Y196 WeakPolarHBondContact O-CE2 3.28Å; L193-Y196 WeakPolarHBondContact O-CB 3.43Å; L193-Y196 PolarHBondContact O-N 3.18Å; D194-Y196 PolarHBondContact O-N 3.12Å
197	G	79.7	Confident	82.9	Confident	37 Å²	37	60.8 Å²	60.8	38%	0.381	30%	0.302	S	S	.	.			trans	92	156	174.8	0	0	0	0	0	114.3	R199 K200 L201	G197-R199 PolarHBondContact O-N 3.1Å; G197-K200 PolarHBondContact O-N 2.69Å; G197-L201 PolarHBondContact O-N 3.17Å
198	L	80.4	Confident	83.7	Confident	27 Å²	27	61.3 Å²	61.3	14%	0.141	31%	0.305	C	S	.	.	H	α-helix	trans	-60.3	-41.4	-167.1	-173.8	64.9	0	0	0	114.2	F45 V49 K200 L201 E202 R273	F45-L198 HydrophobicContact CD1-CD1 4.48Å; F45-L198 HydrophobicContact CD1-CD2 3.86Å; F45-L198 HydrophobicContact CE1-CD1 3.74Å; F45-L198 HydrophobicContact CE1-CD2 3.58Å; F45-L198 HydrophobicContact CE1-CG 4.22Å; V49-L198 HydrophobicContact CG2-CD2 4.46Å; L198-K200 VanDerWaalsContact C-N 3.33Å; L198-K200 PolarHBondContact O-N 2.82Å; L198-L201 HydrophobicContact CD1-CD2 4.37Å; L198-L201 WeakPolarHBondContact O-CB 3.38Å; L198-L201 PolarHBondContact O-N 3.4Å; L198-E202 HydrophobicContact CG-CG 4.36Å; L198-E202 WeakPolarHBondContact CG-OE1 3.16Å; L198-E202 VanDerWaalsContact O-CG 3.32Å; L198-E202 WeakPolarHBondContact O-CG 3.35Å; L198-E202 PolarHBondContact O-N 3.12Å; L198-R273 VanDerWaalsContact CD2-NH1 3.34Å
199	R	85.3	Confident	84.3	Confident	87 Å²	87	56.5 Å²	56.5	33%	0.328	28%	0.284	S	S	.	.	H	α-helix	trans	-65.3	-35	-177.5	-75	-51.9	-157.5	162.3	4	113.7	V49 W65 A66 T68 G197 E202 A203	V49-R199 HydrophobicContact CG2-CG 4.43Å; W65-R199 PolarHBondContact O-NH2 3.3Å; A66-R199 VanDerWaalsContact CA-NH2 3.26Å; A66-R199 PolarHBondContact O-NH2 2.86Å; T68-R199 PolarHBondContact O-NH1 3.31Å; G197-R199 PolarHBondContact O-N 3.1Å; R199-E202 WeakPolarHBondContact CD-OE2 3.37Å; R199-E202 IonicContact CZ-OE2 3.56Å; R199-E202 IonicContact NE-OE2 3.7Å; R199-E202 IonicContact NH1-OE2 3.83Å; R199-E202 PolarHBondContact NH1-OE2 3.27Å; R199-A203 PolarHBondContact O-N 3.48Å; R199-A203 VanDerWaalsContact O-N 3.12Å
200	K	86.2	Confident	85	Confident	138 Å²	138	57 Å²	57	60%	0.6	29%	0.287	S	S	*	.	H	α-helix	trans	-73.5	-37.2	177.1	-67	-175.3	-174.7	169.6	0	110.9	G197 L198 A203 F204	G197-K200 PolarHBondContact O-N 2.69Å; L198-K200 VanDerWaalsContact C-N 3.33Å; L198-K200 PolarHBondContact O-N 2.82Å; K200-A203 PolarHBondContact O-N 3.26Å; K200-F204 PolarHBondContact O-N 3.38Å
201	L	83.8	Confident	85.9	Confident	5 Å²	5	58.3 Å²	58.3	3%	0.026	30%	0.295	C	S	.	.	H	α-helix	trans	-61.6	-47.5	173.1	-171.2	85.7	0	0	0	111.3	L193 G197 L198 A203 F204 F205 Y386	L193-L201 HydrophobicContact CB-CD1 4.28Å; G197-L201 PolarHBondContact O-N 3.17Å; L198-L201 HydrophobicContact CD1-CD2 4.37Å; L198-L201 WeakPolarHBondContact O-CB 3.38Å; L198-L201 PolarHBondContact O-N 3.4Å; L201-A203 VanDerWaalsContact C-N 3.29Å; L201-A203 PolarHBondContact O-N 2.86Å; L201-F204 WeakPolarHBondContact O-CB 3.41Å; L201-F204 PolarHBondContact O-N 2.94Å; L201-F204 VanDerWaalsContact O-N 3.12Å; L201-F205 HydrophobicContact CD1-CE2 4.15Å; L201-F205 HydrophobicContact CD2-CD2 4.39Å; L201-F205 HydrophobicContact CD2-CE2 3.72Å; L201-F205 HydrophobicContact CG-CD2 3.96Å; L201-F205 HydrophobicContact CG-CE2 3.57Å; L201-F205 WeakPolarHBondContact O-CD2 3.26Å; L201-F205 PolarHBondContact O-N 3.38Å; L201-Y386 HydrophobicContact CD2-CE2 3.86Å; L201-Y386 WeakPolarHBondContact CD2-OH 3.44Å
202	E	88.3	Confident	86.8	Confident	16 Å²	16	56.6 Å²	56.6	8%	0.075	29%	0.286	C	S	.	.	H	α-helix	trans	-57	-41.2	174.3	-71.6	170.4	179	0	0	112.3	G69 L73 L198 R199 F205 G206 R273	G69-E202 VanDerWaalsContact CA-CD 3.44Å; L73-E202 HydrophobicContact CD1-CB 4.26Å; L73-E202 HydrophobicContact CD1-CG 3.76Å; L198-E202 HydrophobicContact CG-CG 4.36Å; L198-E202 WeakPolarHBondContact CG-OE1 3.16Å; L198-E202 VanDerWaalsContact O-CG 3.32Å; L198-E202 WeakPolarHBondContact O-CG 3.35Å; L198-E202 PolarHBondContact O-N 3.12Å; R199-E202 WeakPolarHBondContact CD-OE2 3.37Å; R199-E202 IonicContact CZ-OE2 3.56Å; R199-E202 IonicContact NE-OE2 3.7Å; R199-E202 IonicContact NH1-OE2 3.83Å; R199-E202 PolarHBondContact NH1-OE2 3.27Å; E202-F205 PolarHBondContact O-N 3.19Å; E202-G206 PolarHBondContact O-N 2.93Å; E202-R273 IonicContact OE1-CZ 3.47Å; E202-R273 VanDerWaalsContact OE1-CZ 3.27Å; E202-R273 IonicContact OE1-NH1 2.75Å; E202-R273 PolarHBondContact OE1-NH1 2.76Å; E202-R273 IonicContact OE1-NH2 3.38Å; E202-R273 PolarHBondContact OE1-NH2 2.92Å; E202-R273 IonicContact OE2-NH2 2.73Å; E202-R273 PolarHBondContact OE2-NH2 3.15Å
203	A	89.4	Confident	87.5	Confident	68 Å²	68	52.4 Å²	52.4	56%	0.562	27%	0.274	S	S	*	.	H	α-helix	trans	-66.6	-38.7	176	0	0	0	0	0	112.6	R199 K200 L201 G206 F207	R199-A203 PolarHBondContact O-N 3.48Å; R199-A203 VanDerWaalsContact O-N 3.12Å; K200-A203 PolarHBondContact O-N 3.26Å; L201-A203 VanDerWaalsContact C-N 3.29Å; L201-A203 PolarHBondContact O-N 2.86Å; A203-G206 PolarHBondContact O-N 3.2Å; A203-F207 PolarHBondContact O-N 2.9Å
204	F	90	Very high	88.5	Confident	60 Å²	60	55.9 Å²	55.9	26%	0.263	29%	0.292	S	S	.	.	H	α-helix	trans	-62.9	-42.4	175.1	177.1	-103.7	0	0	0	111.7	L193 K200 L201 F207 L208 M382	L193-F204 HydrophobicContact CD1-CD1 4.01Å; L193-F204 HydrophobicContact CD1-CE1 3.86Å; L193-F204 HydrophobicContact CD1-CE2 4.42Å; L193-F204 HydrophobicContact CD1-CG 4.36Å; L193-F204 HydrophobicContact CD1-CZ 4.07Å; K200-F204 PolarHBondContact O-N 3.38Å; L201-F204 WeakPolarHBondContact O-CB 3.41Å; L201-F204 PolarHBondContact O-N 2.94Å; L201-F204 VanDerWaalsContact O-N 3.12Å; F204-F207 WeakPolarHBondContact O-CB 3.2Å; F204-F207 PolarHBondContact O-N 3.07Å; F204-L208 HydrophobicContact CD1-CD1 4.18Å; F204-L208 HydrophobicContact CE1-CD1 3.53Å; F204-L208 HydrophobicContact CE1-CG 4.15Å; F204-L208 HydrophobicContact CZ-CD1 3.87Å; F204-L208 HydrophobicContact CZ-CD2 4.28Å; F204-L208 HydrophobicContact CZ-CG 4.17Å; F204-L208 PolarHBondContact O-N 2.9Å; F204-M382 HydrophobicContact CD1-CE 4.36Å; F204-M382 HydrophobicContact CD1-SD 4.21Å; F204-M382 HydrophobicContact CE1-CE 3.56Å; F204-M382 HydrophobicContact CE1-SD 3.88Å; F204-M382 HydrophobicContact CZ-CE 4.31Å
205	F	88.8	Confident	89.6	Confident	1 Å²	1	55.3 Å²	55.3	0%	0.004	29%	0.289	C	S	.	.	H	α-helix	trans	-63.1	-43.8	172.9	-77.8	-53.2	0	0	0	112.9	L73 I76 L201 E202 F207 L208 I209 M382	L73-F205 HydrophobicContact CD1-CB 4.19Å; L73-F205 HydrophobicContact CD1-CD2 3.57Å; L73-F205 HydrophobicContact CD1-CE2 4.25Å; L73-F205 HydrophobicContact CD1-CG 4.2Å; L73-F205 HydrophobicContact CD2-CD2 4.11Å; L73-F205 HydrophobicContact CD2-CE2 3.96Å; L73-F205 HydrophobicContact CG-CD2 3.58Å; L73-F205 HydrophobicContact CG-CE2 3.77Å; L73-F205 HydrophobicContact CG-CG 4.31Å; I76-F205 HydrophobicContact CD1-CB 3.78Å; I76-F205 HydrophobicContact CD1-CD1 3.13Å; I76-F205 HydrophobicContact CD1-CD2 4.49Å; I76-F205 HydrophobicContact CD1-CE1 3.71Å; I76-F205 HydrophobicContact CD1-CG 3.57Å; L201-F205 HydrophobicContact CD1-CE2 4.15Å; L201-F205 HydrophobicContact CD2-CD2 4.39Å; L201-F205 HydrophobicContact CD2-CE2 3.72Å; L201-F205 HydrophobicContact CG-CD2 3.96Å; L201-F205 HydrophobicContact CG-CE2 3.57Å; L201-F205 WeakPolarHBondContact O-CD2 3.26Å; L201-F205 PolarHBondContact O-N 3.38Å; E202-F205 PolarHBondContact O-N 3.19Å; F205-F207 PolarHBondContact O-N 2.87Å; F205-L208 PolarHBondContact O-N 3.03Å; F205-L208 VanDerWaalsContact O-N 3.13Å; F205-I209 WeakPolarHBondContact O-CG1 3.49Å; F205-I209 PolarHBondContact O-N 2.89Å; F205-M382 HydrophobicContact CE1-CB 3.73Å; F205-M382 HydrophobicContact CE1-CG 4.22Å; F205-M382 HydrophobicContact CE1-SD 3.78Å; F205-M382 HydrophobicContact CZ-CB 3.45Å; F205-M382 VanDerWaalsContact CZ-CB 3.45Å; F205-M382 HydrophobicContact CZ-CG 4.19Å; F205-M382 HydrophobicContact CZ-SD 3.8Å
206	G	92.1	Very high	90.5	Very high	26 Å²	26	46.8 Å²	46.8	27%	0.268	25%	0.252	S	S	.	.	H	α-helix	trans	-57.3	-36.8	172.8	0	0	0	0	0	112.6	E202 A203 T210	E202-G206 PolarHBondContact O-N 2.93Å; A203-G206 PolarHBondContact O-N 3.2Å; G206-T210 WeakPolarHBondContact O-CB 3.22Å; G206-T210 PolarHBondContact O-N 2.94Å; G206-T210 PolarHBondContact O-OG1 2.76Å
207	F	94.2	Very high	91.4	Very high	124 Å²	124	42 Å²	42	54%	0.544	24%	0.237	S	C	.	.	H	α-helix	trans	-64	-48.4	172.6	167.3	-100.6	0	0	0	112.2	A203 F204 F205 I209 T210 V211	A203-F207 PolarHBondContact O-N 2.9Å; F204-F207 WeakPolarHBondContact O-CB 3.2Å; F204-F207 PolarHBondContact O-N 3.07Å; F205-F207 PolarHBondContact O-N 2.87Å; F207-I209 PolarHBondContact O-N 3.08Å; F207-T210 WeakPolarHBondContact O-CB 3.38Å; F207-T210 PolarHBondContact O-N 2.9Å; F207-T210 VanDerWaalsContact O-N 3.14Å; F207-V211 HydrophobicContact CD2-CG2 4.37Å; F207-V211 HydrophobicContact CE1-CG2 4.07Å; F207-V211 HydrophobicContact CE2-CG2 3.89Å; F207-V211 HydrophobicContact CZ-CG2 3.73Å; F207-V211 WeakPolarHBondContact O-CG2 3.2Å; F207-V211 PolarHBondContact O-N 2.81Å
208	L	94.1	Very high	92.2	Very high	13 Å²	13	45.1 Å²	45.1	7%	0.068	24%	0.238	C	C	.	.	H	α-helix	trans	-61.4	-42.2	177.9	-66.7	-179.9	0	0	0	112.4	F204 F205 T210 V211 M212 A375	F204-L208 HydrophobicContact CD1-CD1 4.18Å; F204-L208 HydrophobicContact CE1-CD1 3.53Å; F204-L208 HydrophobicContact CE1-CG 4.15Å; F204-L208 HydrophobicContact CZ-CD1 3.87Å; F204-L208 HydrophobicContact CZ-CD2 4.28Å; F204-L208 HydrophobicContact CZ-CG 4.17Å; F204-L208 PolarHBondContact O-N 2.9Å; F205-L208 PolarHBondContact O-N 3.03Å; F205-L208 VanDerWaalsContact O-N 3.13Å; L208-T210 VanDerWaalsContact C-N 3.29Å; L208-T210 PolarHBondContact O-N 2.93Å; L208-V211 WeakPolarHBondContact O-CB 3.45Å; L208-V211 PolarHBondContact O-N 3.34Å; L208-M212 WeakPolarHBondContact O-CG 3.39Å; L208-M212 PolarHBondContact O-N 2.88Å; L208-A375 HydrophobicContact CD2-CB 4.17Å
209	I	94.7	Very high	92.9	Very high	6 Å²	6	44 Å²	44	3%	0.031	23%	0.232	C	C	.	.	H	α-helix	trans	-61.1	-40.9	174.6	-64.3	168.2	0	0	0	110.9	F72 I76 L79 F205 F207 M212 A213 V300 I304	F72-I209 HydrophobicContact CB-CD1 4.35Å; F72-I209 HydrophobicContact CD1-CD1 4.01Å; I76-I209 HydrophobicContact CD1-CD1 4.38Å; I76-I209 HydrophobicContact CG1-CD1 3.86Å; I76-I209 HydrophobicContact CG1-CG1 4Å; L79-I209 HydrophobicContact CD1-CG2 4.38Å; F205-I209 WeakPolarHBondContact O-CG1 3.49Å; F205-I209 PolarHBondContact O-N 2.89Å; F207-I209 PolarHBondContact O-N 3.08Å; I209-M212 HydrophobicContact CB-CE 4.41Å; I209-M212 HydrophobicContact CG1-CE 4.04Å; I209-M212 PolarHBondContact O-N 2.7Å; I209-A213 WeakPolarHBondContact O-CB 3.41Å; I209-A213 PolarHBondContact O-N 3.41Å; I209-V300 HydrophobicContact CG2-CG1 4.06Å; I209-I304 HydrophobicContact CG2-CD1 4.39Å
210	T	96	Very high	93.4	Very high	74 Å²	74	41.1 Å²	41.1	45%	0.454	22%	0.221	S	C	.	.	H	α-helix	trans	-64.5	-40.6	176.9	-57.6	0	0	0	0	111.4	G206 F207 L208 A213 I214	G206-T210 WeakPolarHBondContact O-CB 3.22Å; G206-T210 PolarHBondContact O-N 2.94Å; G206-T210 PolarHBondContact O-OG1 2.76Å; F207-T210 WeakPolarHBondContact O-CB 3.38Å; F207-T210 PolarHBondContact O-N 2.9Å; F207-T210 VanDerWaalsContact O-N 3.14Å; L208-T210 VanDerWaalsContact C-N 3.29Å; L208-T210 PolarHBondContact O-N 2.93Å; T210-A213 PolarHBondContact O-N 2.94Å; T210-I214 HydrophobicContact CG2-CD1 3.78Å; T210-I214 HydrophobicContact CG2-CG1 4.38Å; T210-I214 WeakPolarHBondContact O-CB 3.36Å; T210-I214 VanDerWaalsContact O-CG1 3.29Å; T210-I214 WeakPolarHBondContact O-CG1 3.24Å; T210-I214 PolarHBondContact O-N 3.16Å
211	V	96.9	Very high	93.9	Very high	29 Å²	29	39.5 Å²	39.5	18%	0.176	22%	0.222	C	C	.	.	H	α-helix	trans	-59.7	-47.3	174.1	171.8	0	0	0	0	110.5	F207 L208 A213 I214 S215 V371 A375	F207-V211 HydrophobicContact CD2-CG2 4.37Å; F207-V211 HydrophobicContact CE1-CG2 4.07Å; F207-V211 HydrophobicContact CE2-CG2 3.89Å; F207-V211 HydrophobicContact CZ-CG2 3.73Å; F207-V211 WeakPolarHBondContact O-CG2 3.2Å; F207-V211 PolarHBondContact O-N 2.81Å; L208-V211 WeakPolarHBondContact O-CB 3.45Å; L208-V211 PolarHBondContact O-N 3.34Å; V211-A213 PolarHBondContact O-N 2.99Å; V211-I214 PolarHBondContact O-N 3.48Å; V211-S215 WeakPolarHBondContact O-CB 3.21Å; V211-S215 PolarHBondContact O-N 3.41Å; V211-S215 PolarHBondContact O-OG 3.22Å; V211-V371 HydrophobicContact CG1-CG1 3.8Å; V211-A375 HydrophobicContact CB-CB 4.25Å; V211-A375 HydrophobicContact CG1-CB 3.87Å
212	M	96.1	Very high	94.4	Very high	0 Å²	0	42 Å²	42	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-60.4	-46.6	176.2	-68.9	-174	-77.4	0	0	112.2	L79 L208 I209 I214 S215 F216 I304 A375 A376	L79-M212 HydrophobicContact CB-CE 4Å; L79-M212 HydrophobicContact CB-SD 3.99Å; L79-M212 HydrophobicContact CD1-CE 3.83Å; L79-M212 HydrophobicContact CD1-SD 4.49Å; L208-M212 WeakPolarHBondContact O-CG 3.39Å; L208-M212 PolarHBondContact O-N 2.88Å; I209-M212 HydrophobicContact CB-CE 4.41Å; I209-M212 HydrophobicContact CG1-CE 4.04Å; I209-M212 PolarHBondContact O-N 2.7Å; M212-I214 VanDerWaalsContact C-N 3.33Å; M212-I214 PolarHBondContact O-N 3.23Å; M212-S215 PolarHBondContact O-N 3.18Å; M212-F216 HydrophobicContact CB-CD2 4.07Å; M212-F216 HydrophobicContact CB-CE2 3.93Å; M212-F216 HydrophobicContact CG-CE2 4.14Å; M212-F216 WeakPolarHBondContact O-CD2 3.24Å; M212-F216 PolarHBondContact O-N 3.46Å; M212-I304 HydrophobicContact CB-CD1 4.37Å; M212-A375 HydrophobicContact CG-CB 3.89Å; M212-A376 WeakPolarHBondContact SD-CA 3.32Å; M212-A376 HydrophobicContact SD-CB 3.61Å
213	A	96.8	Very high	94.6	Very high	32 Å²	32	42 Å²	42	26%	0.264	24%	0.236	S	C	.	.	H	α-helix	trans	-60.3	-41.6	179.1	0	0	0	0	0	112.5	I209 T210 V211 G217 I304	I209-A213 WeakPolarHBondContact O-CB 3.41Å; I209-A213 PolarHBondContact O-N 3.41Å; T210-A213 PolarHBondContact O-N 2.94Å; V211-A213 PolarHBondContact O-N 2.99Å; A213-G217 WeakPolarHBondContact O-CA 3.15Å; A213-G217 PolarHBondContact O-N 3.27Å; A213-I304 HydrophobicContact CB-CD1 4.01Å; A213-I304 HydrophobicContact CB-CG1 4.16Å
214	I	97.4	Very high	94.8	Very high	115 Å²	115	46.6 Å²	46.6	59%	0.59	24%	0.244	S	C	*	.	H	α-helix	trans	-70.8	-45.4	177.4	-67.6	170.4	0	0	0	110.6	T210 V211 M212 Y218	T210-I214 HydrophobicContact CG2-CD1 3.78Å; T210-I214 HydrophobicContact CG2-CG1 4.38Å; T210-I214 WeakPolarHBondContact O-CB 3.36Å; T210-I214 VanDerWaalsContact O-CG1 3.29Å; T210-I214 WeakPolarHBondContact O-CG1 3.24Å; T210-I214 PolarHBondContact O-N 3.16Å; V211-I214 PolarHBondContact O-N 3.48Å; M212-I214 VanDerWaalsContact C-N 3.33Å; M212-I214 PolarHBondContact O-N 3.23Å; I214-Y218 VanDerWaalsContact O-CB 3.24Å; I214-Y218 WeakPolarHBondContact O-CB 3.47Å; I214-Y218 PolarHBondContact O-N 2.93Å
215	S	96.6	Very high	95	Very high	9 Å²	9	43.9 Å²	43.9	6%	0.063	23%	0.233	C	C	.	.	H	α-helix	trans	-62.4	-56.3	-178.7	-71.2	0	0	0	0	111.8	V211 M212 G217 Y218 E219 I368	V211-S215 WeakPolarHBondContact O-CB 3.21Å; V211-S215 PolarHBondContact O-N 3.41Å; V211-S215 PolarHBondContact O-OG 3.22Å; M212-S215 PolarHBondContact O-N 3.18Å; S215-G217 VanDerWaalsContact C-N 3.34Å; S215-G217 PolarHBondContact O-N 3.03Å; S215-Y218 WeakPolarHBondContact O-CB 3.35Å; S215-Y218 PolarHBondContact O-N 3.03Å; S215-E219 PolarHBondContact O-N 3.27Å; S215-I368 WeakPolarHBondContact O-CG2 3.42Å; S215-I368 PolarHBondContact OG-O 3.01Å
216	F	96.4	Very high	95.2	Very high	3 Å²	3	47.9 Å²	47.9	1%	0.013	25%	0.254	C	S	.	.	H	α-helix	trans	-72.1	-30.2	-178.7	-56.1	-48.4	0	0	0	112.1	I84 M212 E219 Y220 I304 F307 V308 W369 I373	I84-F216 HydrophobicContact CD1-CE2 3.85Å; I84-F216 HydrophobicContact CD1-CZ 3.79Å; M212-F216 HydrophobicContact CB-CD2 4.07Å; M212-F216 HydrophobicContact CB-CE2 3.93Å; M212-F216 HydrophobicContact CG-CE2 4.14Å; M212-F216 WeakPolarHBondContact O-CD2 3.24Å; M212-F216 PolarHBondContact O-N 3.46Å; F216-E219 PolarHBondContact O-N 3Å; F216-Y220 WeakPolarHBondContact O-CB 3.18Å; F216-Y220 PolarHBondContact O-N 3.11Å; F216-I304 HydrophobicContact CB-CG2 4.36Å; F216-I304 HydrophobicContact CD2-CG2 3.45Å; F216-I304 VanDerWaalsContact CD2-CG2 3.45Å; F216-I304 HydrophobicContact CE2-CG2 4.16Å; F216-I304 HydrophobicContact CG-CG2 4.31Å; F216-F307 HydrophobicContact CB-CB 4.35Å; F216-V308 HydrophobicContact CB-CG2 4.32Å; F216-V308 HydrophobicContact CD1-CG2 4.2Å; F216-V308 HydrophobicContact CD2-CG2 4.3Å; F216-V308 HydrophobicContact CG-CG2 4.02Å; F216-W369 AromaticContact CD1-CE3 3.8Å; F216-W369 HydrophobicContact CD1-CE3 3.8Å; F216-W369 AromaticContact CD1-CZ3 3.68Å; F216-W369 HydrophobicContact CD1-CZ3 3.68Å; F216-W369 HydrophobicContact CE1-CD2 4.37Å; F216-W369 AromaticContact CE1-CE3 3.52Å; F216-W369 HydrophobicContact CE1-CE3 3.52Å; F216-W369 HydrophobicContact CE1-CH2 4.26Å; F216-W369 AromaticContact CE1-CZ3 3.43Å; F216-W369 HydrophobicContact CE1-CZ3 3.43Å; F216-W369 VanDerWaalsContact CE1-CZ3 3.43Å; F216-W369 HydrophobicContact CZ-CZ3 4.47Å; F216-I373 HydrophobicContact CE1-CD1 4.41Å; F216-I373 HydrophobicContact CZ-CD1 4.16Å
217	G	96.8	Very high	95.3	Very high	12 Å²	12	51.3 Å²	51.3	12%	0.124	26%	0.263	C	S	.	.	H	α-helix	trans	-65.7	-36.7	171.3	0	0	0	0	0	112.9	A213 S215 Y220 V221	A213-G217 WeakPolarHBondContact O-CA 3.15Å; A213-G217 PolarHBondContact O-N 3.27Å; S215-G217 VanDerWaalsContact C-N 3.34Å; S215-G217 PolarHBondContact O-N 3.03Å; G217-Y220 PolarHBondContact O-N 2.95Å; G217-V221 WeakPolarHBondContact O-CG2 3.49Å; G217-V221 PolarHBondContact O-N 3.13Å
218	Y	96.6	Very high	95.2	Very high	103 Å²	103	47.5 Å²	47.5	40%	0.404	26%	0.258	S	S	.	.	H	α-helix	trans	-63.4	-46.9	173.6	175.8	-91.3	0	0	0	111.2	I214 S215 Y220 V221 L222 I368	I214-Y218 VanDerWaalsContact O-CB 3.24Å; I214-Y218 WeakPolarHBondContact O-CB 3.47Å; I214-Y218 PolarHBondContact O-N 2.93Å; S215-Y218 WeakPolarHBondContact O-CB 3.35Å; S215-Y218 PolarHBondContact O-N 3.03Å; Y218-Y220 VanDerWaalsContact C-N 3.3Å; Y218-Y220 PolarHBondContact O-N 2.87Å; Y218-V221 PolarHBondContact O-N 2.84Å; Y218-L222 HydrophobicContact CE1-CD2 3.8Å; Y218-L222 WeakPolarHBondContact O-CB 3.3Å; Y218-L222 PolarHBondContact O-N 3.37Å; Y218-I368 HydrophobicContact CD1-CD1 3.42Å; Y218-I368 VanDerWaalsContact CD1-CD1 3.42Å; Y218-I368 HydrophobicContact CD1-CG2 4.16Å; Y218-I368 HydrophobicContact CE1-CD1 3.38Å; Y218-I368 HydrophobicContact CG-CD1 4.07Å
219	E	94.9	Very high	95.1	Very high	2 Å²	2	51.1 Å²	51.1	1%	0.009	28%	0.275	C	S	.	.	H	α-helix	trans	-56.8	-44.9	174.8	-64.6	-54.7	143.5	0	0	111.4	S215 F216 V221 L222 V223 V311 A365	S215-E219 PolarHBondContact O-N 3.27Å; F216-E219 PolarHBondContact O-N 3Å; E219-V221 PolarHBondContact O-N 3.41Å; E219-L222 PolarHBondContact O-N 2.95Å; E219-V223 WeakPolarHBondContact O-CB 3.41Å; E219-V223 WeakPolarHBondContact O-CG2 3.46Å; E219-V223 PolarHBondContact O-N 3.5Å; E219-V311 HydrophobicContact CB-CG1 4.47Å; E219-V311 HydrophobicContact CB-CG2 4.01Å; E219-A365 WeakPolarHBondContact OE1-CA 3.15Å; E219-A365 WeakPolarHBondContact OE1-CB 3.16Å; E219-A365 VanDerWaalsContact OE1-O 3.04Å; E219-A365 WeakPolarHBondContact OE2-CB 3.41Å
220	Y	96.2	Very high	95	Very high	28 Å²	28	51 Å²	51	11%	0.11	28%	0.275	C	S	.	.	H	α-helix	trans	-58.9	-44.5	177.7	-175.3	-93.2	0	0	0	112.9	F216 G217 Y218 K224 P225 Q227 F307 A310 V311	F216-Y220 WeakPolarHBondContact O-CB 3.18Å; F216-Y220 PolarHBondContact O-N 3.11Å; G217-Y220 PolarHBondContact O-N 2.95Å; Y218-Y220 VanDerWaalsContact C-N 3.3Å; Y218-Y220 PolarHBondContact O-N 2.87Å; Y220-K224 PolarHBondContact O-N 3.33Å; Y220-K224 VanDerWaalsContact O-N 3.14Å; Y220-P225 HydrophobicContact CD2-CG 3.92Å; Y220-P225 HydrophobicContact CE2-CB 4.33Å; Y220-P225 HydrophobicContact CE2-CG 3.82Å; Y220-P225 WeakPolarHBondContact O-CD 3.36Å; Y220-Q227 VanDerWaalsContact OH-CD 3.31Å; Y220-Q227 PolarHBondContact OH-NE2 3.48Å; Y220-Q227 PolarHBondContact OH-OE1 3.23Å; Y220-F307 AromaticContact CD1-CD1 3.95Å; Y220-F307 HydrophobicContact CD1-CD1 3.95Å; Y220-F307 HydrophobicContact CD1-CE1 4.01Å; Y220-F307 HydrophobicContact CD2-CB 4.2Å; Y220-F307 AromaticContact CD2-CD1 3.64Å; Y220-F307 HydrophobicContact CD2-CD1 3.64Å; Y220-F307 HydrophobicContact CD2-CE1 4.46Å; Y220-F307 HydrophobicContact CD2-CG 4.28Å; Y220-F307 HydrophobicContact CE1-CD1 4.36Å; Y220-F307 HydrophobicContact CE1-CE1 4.28Å; Y220-F307 HydrophobicContact CE2-CD1 4.05Å; Y220-F307 HydrophobicContact CG-CB 4.36Å; Y220-F307 AromaticContact CG-CD1 3.55Å; Y220-F307 HydrophobicContact CG-CD1 3.55Å; Y220-F307 HydrophobicContact CG-CE1 4.1Å; Y220-F307 HydrophobicContact CG-CG 4.15Å; Y220-A310 HydrophobicContact CD2-CB 3.99Å; Y220-A310 HydrophobicContact CE2-CB 3.56Å; Y220-V311 VanDerWaalsContact CA-CG2 3.46Å; Y220-V311 HydrophobicContact CD2-CG2 4.41Å
221	V	95.8	Very high	94.9	Very high	103 Å²	103	52 Å²	52	62%	0.624	28%	0.277	S	S	*	.	H	α-helix	trans	-69.7	-34	178.2	173.1	0	0	0	0	111.8	G217 Y218 E219 K224	G217-V221 WeakPolarHBondContact O-CG2 3.49Å; G217-V221 PolarHBondContact O-N 3.13Å; Y218-V221 PolarHBondContact O-N 2.84Å; E219-V221 PolarHBondContact O-N 3.41Å; V221-K224 WeakPolarHBondContact O-CG 3.46Å
222	L	94.6	Very high	94.7	Very high	59 Å²	59	55.9 Å²	55.9	31%	0.309	29%	0.291	S	S	.	.	H	α-helix	trans	-71	-45.9	180	-175	60.7	0	0	0	111.8	Y218 E219 K224 F361 A365	Y218-L222 HydrophobicContact CE1-CD2 3.8Å; Y218-L222 WeakPolarHBondContact O-CB 3.3Å; Y218-L222 PolarHBondContact O-N 3.37Å; E219-L222 PolarHBondContact O-N 2.95Å; L222-K224 VanDerWaalsContact C-N 3.32Å; L222-K224 PolarHBondContact O-N 2.88Å; L222-F361 HydrophobicContact CD2-CB 3.64Å; L222-F361 HydrophobicContact CD2-CG 4.34Å; L222-F361 HydrophobicContact CG-CB 4.11Å; L222-F361 HydrophobicContact CG-CD1 4.15Å; L222-F361 HydrophobicContact CG-CG 4.39Å; L222-A365 HydrophobicContact CD2-CB 4.15Å
223	V	92.9	Very high	94.3	Very high	14 Å²	14	55.9 Å²	55.9	9%	0.085	29%	0.291	C	S	.	.	H	α-helix	trans	-72.4	-27	-178	175.4	0	0	0	0	111.8	E219 P225 V311 Q314 L357 F361	E219-V223 WeakPolarHBondContact O-CB 3.41Å; E219-V223 WeakPolarHBondContact O-CG2 3.46Å; E219-V223 PolarHBondContact O-N 3.5Å; V223-P225 HydrophobicContact CG1-CG 4.27Å; V223-V311 HydrophobicContact CB-CG2 4.33Å; V223-V311 HydrophobicContact CG2-CG1 3.98Å; V223-V311 HydrophobicContact CG2-CG2 4.21Å; V223-Q314 HydrophobicContact CG1-CB 3.77Å; V223-Q314 HydrophobicContact CG1-CG 3.78Å; V223-L357 HydrophobicContact CG2-CD2 4.44Å; V223-F361 HydrophobicContact CB-CE1 4.32Å; V223-F361 HydrophobicContact CB-CZ 4.11Å; V223-F361 HydrophobicContact CG1-CZ 3.99Å; V223-F361 HydrophobicContact CG2-CD1 4.37Å; V223-F361 HydrophobicContact CG2-CD2 4.07Å; V223-F361 HydrophobicContact CG2-CE1 3.98Å; V223-F361 HydrophobicContact CG2-CE2 3.68Å; V223-F361 HydrophobicContact CG2-CG 4.41Å; V223-F361 HydrophobicContact CG2-CZ 3.63Å
224	K	93.6	Very high	94.1	Very high	165 Å²	165	55.4 Å²	55.4	72%	0.717	28%	0.284	S	S	*	.			trans	49.7	61.2	-178	-58.4	178.1	-177.3	172.4	0	113.6	Y220 V221 L222	Y220-K224 PolarHBondContact O-N 3.33Å; Y220-K224 VanDerWaalsContact O-N 3.14Å; V221-K224 WeakPolarHBondContact O-CG 3.46Å; L222-K224 VanDerWaalsContact C-N 3.32Å; L222-K224 PolarHBondContact O-N 2.88Å
225	P	92.8	Very high	93.8	Very high	4 Å²	4	56.5 Å²	56.5	3%	0.026	29%	0.285	C	S	.	.			trans	-56.6	148.5	173.1	-21.9	33.6	0	0	0	112.2	F96 Y220 V223 Q227 V230 A310 Q314	F96-P225 HydrophobicContact CE1-CB 4.33Å; F96-P225 HydrophobicContact CZ-CB 4.3Å; Y220-P225 HydrophobicContact CD2-CG 3.92Å; Y220-P225 HydrophobicContact CE2-CB 4.33Å; Y220-P225 HydrophobicContact CE2-CG 3.82Å; Y220-P225 WeakPolarHBondContact O-CD 3.36Å; V223-P225 HydrophobicContact CG1-CG 4.27Å; P225-Q227 PolarHBondContact O-N 3.28Å; P225-Q227 PolarHBondContact O-NE2 2.98Å; P225-V230 HydrophobicContact CB-CG2 4.17Å; P225-A310 HydrophobicContact CB-CB 4.18Å; P225-A310 HydrophobicContact CG-CB 4.07Å; P225-Q314 HydrophobicContact CB-CB 4.32Å; P225-Q314 HydrophobicContact CG-CB 4.37Å
226	D	93.5	Very high	93.4	Very high	85 Å²	85	60.9 Å²	60.9	46%	0.455	31%	0.307	S	S	.	.			trans	-63.6	111.2	175.4	-171.5	-27.3	0	0	0	110.4	G228 E229 V230	D226-G228 PolarHBondContact O-N 3.42Å; D226-G228 WeakPolarHBondContact OD1-CA 3.37Å; D226-G228 PolarHBondContact OD1-N 3.31Å; D226-E229 HydrophobicContact CB-CB 4.19Å; D226-E229 HydrophobicContact CB-CG 4.08Å; D226-E229 PolarHBondContact O-N 3.4Å; D226-E229 PolarHBondContact OD1-N 3.22Å; D226-V230 WeakPolarHBondContact O-CG2 3.38Å; D226-V230 PolarHBondContact O-N 2.92Å
227	Q	93.5	Very high	92.7	Very high	97 Å²	97	65.3 Å²	65.3	45%	0.453	34%	0.336	S	S	.	.	H	α-helix	trans	-62.6	-32	-178.3	-57.9	-58.7	-55.6	0	0	112.3	Y220 P225 L231	Y220-Q227 VanDerWaalsContact OH-CD 3.31Å; Y220-Q227 PolarHBondContact OH-NE2 3.48Å; Y220-Q227 PolarHBondContact OH-OE1 3.23Å; P225-Q227 PolarHBondContact O-N 3.28Å; P225-Q227 PolarHBondContact O-NE2 2.98Å; Q227-L231 WeakPolarHBondContact O-CB 3.4Å; Q227-L231 VanDerWaalsContact O-CG 3.29Å; Q227-L231 WeakPolarHBondContact O-CG 3.36Å; Q227-L231 PolarHBondContact O-N 3.1Å
228	G	93.1	Very high	91.9	Very high	44 Å²	44	67.7 Å²	67.7	45%	0.454	34%	0.341	S	S	.	.	H	α-helix	trans	-65.6	-43.4	176.2	0	0	0	0	0	111.4	D226 K232	D226-G228 PolarHBondContact O-N 3.42Å; D226-G228 WeakPolarHBondContact OD1-CA 3.37Å; D226-G228 PolarHBondContact OD1-N 3.31Å; G228-K232 WeakPolarHBondContact O-CB 3.3Å; G228-K232 PolarHBondContact O-N 2.83Å
229	E	91.4	Very high	90.7	Very high	90 Å²	90	65.5 Å²	65.5	42%	0.421	34%	0.341	S	S	.	.	H	α-helix	trans	-71.2	-38.7	177.4	-63.6	-159.1	154.1	0	0	112.7	F96 D226 K232 G233	F96-E229 HydrophobicContact CD2-CB 3.7Å; F96-E229 VanDerWaalsContact CD2-OE2 3.22Å; F96-E229 WeakPolarHBondContact CD2-OE2 3.2Å; F96-E229 HydrophobicContact CE2-CB 4.05Å; F96-E229 VanDerWaalsContact CE2-OE2 3.24Å; F96-E229 WeakPolarHBondContact CE2-OE2 3.24Å; F96-E229 HydrophobicContact CG-CB 4.14Å; D226-E229 HydrophobicContact CB-CB 4.19Å; D226-E229 HydrophobicContact CB-CG 4.08Å; D226-E229 PolarHBondContact O-N 3.4Å; D226-E229 PolarHBondContact OD1-N 3.22Å; E229-K232 PolarHBondContact O-N 3.49Å; E229-G233 PolarHBondContact O-N 2.94Å
230	V	93.9	Very high	89.5	Confident	4 Å²	4	68.1 Å²	68.1	2%	0.024	36%	0.363	C	S	.	.	H	α-helix	trans	-60.1	-52	174.7	172.4	0	0	0	0	110.6	F96 L99 P225 D226 K232 G233 M234 V306 A310	F96-V230 HydrophobicContact CD1-CG2 3.74Å; F96-V230 HydrophobicContact CE1-CG2 3.51Å; F96-V230 HydrophobicContact CZ-CG2 4.39Å; L99-V230 HydrophobicContact CD1-CB 4.45Å; L99-V230 HydrophobicContact CD1-CG1 4.11Å; P225-V230 HydrophobicContact CB-CG2 4.17Å; D226-V230 WeakPolarHBondContact O-CG2 3.38Å; D226-V230 PolarHBondContact O-N 2.92Å; V230-K232 VanDerWaalsContact C-N 3.33Å; V230-K232 PolarHBondContact O-N 3.06Å; V230-G233 PolarHBondContact O-N 3.01Å; V230-M234 HydrophobicContact CG1-SD 3.8Å; V230-M234 VanDerWaalsContact O-CG 3.23Å; V230-M234 WeakPolarHBondContact O-CG 3.39Å; V230-M234 PolarHBondContact O-N 3.15Å; V230-V306 HydrophobicContact CG1-CG1 4.17Å; V230-A310 HydrophobicContact CG2-CB 3.93Å
231	L	93.8	Very high	88.4	Confident	94 Å²	94	74.1 Å²	74.1	49%	0.492	40%	0.397	S	S	.	.	H	α-helix	trans	-63.8	-39.6	179.1	-71.7	172.9	0	0	0	112	Q227 M234 F235	Q227-L231 WeakPolarHBondContact O-CB 3.4Å; Q227-L231 VanDerWaalsContact O-CG 3.29Å; Q227-L231 WeakPolarHBondContact O-CG 3.36Å; Q227-L231 PolarHBondContact O-N 3.1Å; L231-M234 PolarHBondContact O-N 3.25Å; L231-F235 HydrophobicContact CD2-CE2 4.1Å; L231-F235 WeakPolarHBondContact O-CD2 3.36Å; L231-F235 PolarHBondContact O-N 2.91Å; L231-F235 VanDerWaalsContact O-N 3.14Å
232	K	91.4	Very high	87.6	Confident	110 Å²	110	71.3 Å²	71.3	48%	0.478	38%	0.381	S	S	.	.	H	α-helix	trans	-61.7	-47.2	174.8	-171.7	-174.2	177.8	-178.7	0	110.7	G228 E229 V230 M234 L236 Y238	G228-K232 WeakPolarHBondContact O-CB 3.3Å; G228-K232 PolarHBondContact O-N 2.83Å; E229-K232 PolarHBondContact O-N 3.49Å; V230-K232 VanDerWaalsContact C-N 3.33Å; V230-K232 PolarHBondContact O-N 3.06Å; K232-M234 VanDerWaalsContact C-N 3.28Å; K232-M234 PolarHBondContact O-N 3.38Å; K232-L236 HydrophobicContact CB-CD1 4.5Å; K232-L236 HydrophobicContact CG-CD1 3.67Å; K232-L236 WeakPolarHBondContact O-CB 3.38Å; K232-L236 PolarHBondContact O-N 3.2Å; K232-Y238 HydrophobicContact CD-CE1 4.25Å; K232-Y238 HydrophobicContact CG-CE1 3.9Å
233	G	89.2	Confident	87	Confident	0 Å²	0	69.8 Å²	69.8	0%	0	38%	0.38	C	S	.	.	H	α-helix	trans	-61.8	-32.7	178	0	0	0	0	0	113.7	F96 W100 E229 V230	F96-G233 VanDerWaalsContact O-CA 3.23Å; F96-G233 WeakPolarHBondContact O-CA 3.45Å; W100-G233 WeakPolarHBondContact CB-O 3.45Å; W100-G233 PolarHBondContact N-O 3.1Å; E229-G233 PolarHBondContact O-N 2.94Å; V230-G233 PolarHBondContact O-N 3.01Å
234	M	90.8	Very high	86.4	Confident	23 Å²	23	73.9 Å²	73.9	11%	0.113	41%	0.407	C	S	.	.	H	α-helix	trans	-75.7	-44.5	179.2	-71.5	167.3	72.8	0	0	113.4	L99 W100 L103 V230 L231 K232 F302 V306	L99-M234 HydrophobicContact CB-CG 3.89Å; L99-M234 HydrophobicContact CD1-CG 4.16Å; L99-M234 HydrophobicContact CG-CG 4.46Å; W100-M234 WeakPolarHBondContact CA-O 3.22Å; W100-M234 WeakPolarHBondContact CB-O 3.21Å; L103-M234 WeakPolarHBondContact CD2-O 3.07Å; V230-M234 HydrophobicContact CG1-SD 3.8Å; V230-M234 VanDerWaalsContact O-CG 3.23Å; V230-M234 WeakPolarHBondContact O-CG 3.39Å; V230-M234 PolarHBondContact O-N 3.15Å; L231-M234 PolarHBondContact O-N 3.25Å; K232-M234 VanDerWaalsContact C-N 3.28Å; K232-M234 PolarHBondContact O-N 3.38Å; M234-F302 HydrophobicContact CE-CE1 3.68Å; M234-F302 HydrophobicContact CE-CZ 3.64Å; M234-V306 HydrophobicContact CE-CG2 4.37Å; M234-V306 HydrophobicContact SD-CG1 4.33Å
235	F	91.6	Very high	85.8	Confident	137 Å²	137	69.2 Å²	69.2	60%	0.601	39%	0.392	S	S	*	.	H	α-helix	trans	-103.8	-20.3	-169	-68.1	-73	0	0	0	114.7	L103 L231 P237	L103-F235 HydrophobicContact CD2-CD1 4.29Å; L103-F235 HydrophobicContact CD2-CE1 4.16Å; L231-F235 HydrophobicContact CD2-CE2 4.1Å; L231-F235 WeakPolarHBondContact O-CD2 3.36Å; L231-F235 PolarHBondContact O-N 2.91Å; L231-F235 VanDerWaalsContact O-N 3.14Å; F235-P237 WeakPolarHBondContact O-CD 3.33Å
236	L	88.1	Confident	85.5	Confident	101 Å²	101	70.8 Å²	70.8	53%	0.529	40%	0.399	S	S	.	.	S	Bend	trans	-101.5	113.6	175	-76.1	141	0	0	0	109.1	K232 Y238	K232-L236 HydrophobicContact CB-CD1 4.5Å; K232-L236 HydrophobicContact CG-CD1 3.67Å; K232-L236 WeakPolarHBondContact O-CB 3.38Å; K232-L236 PolarHBondContact O-N 3.2Å; L236-Y238 HydrophobicContact CB-CD1 4.06Å; L236-Y238 VanDerWaalsContact O-CD1 3.26Å; L236-Y238 WeakPolarHBondContact O-CD1 3.38Å; L236-Y238 PolarHBondContact O-N 2.91Å
237	P	82.9	Confident	84.9	Confident	96 Å²	96	71.5 Å²	71.5	62%	0.623	40%	0.402	S	S	*	.			trans	-69.7	96.5	170	28.5	-31.8	0	0	0	108.3	W100 F235	W100-P237 HydrophobicContact CD2-CB 3.92Å; W100-P237 HydrophobicContact CE3-CB 4.15Å; W100-P237 HydrophobicContact CG-CB 4.24Å; F235-P237 WeakPolarHBondContact O-CD 3.33Å
238	Y	78.6	Confident	84.3	Confident	62 Å²	62	71.1 Å²	71.1	24%	0.243	40%	0.4	C	S	.	.			trans	-132	131.5	173.9	76.7	-87.4	0	0	0	110.2	K97 K232 L236	K97-Y238 HydrophobicContact CG-CE2 3.92Å; K232-Y238 HydrophobicContact CD-CE1 4.25Å; K232-Y238 HydrophobicContact CG-CE1 3.9Å; L236-Y238 HydrophobicContact CB-CD1 4.06Å; L236-Y238 VanDerWaalsContact O-CD1 3.26Å; L236-Y238 WeakPolarHBondContact O-CD1 3.38Å; L236-Y238 PolarHBondContact O-N 2.91Å
239	C	73.1	Confident	83.9	Confident	57 Å²	57	69.6 Å²	69.6	39%	0.385	38%	0.382	S	S	.	.			trans	-136.2	61	176.8	-136.1	0	0	0	0	108.6	D241 C242	C239-D241 PolarHBondContact O-N 3.16Å; C239-C242 VanDerWaalsContact C-SG 3.58Å; C239-C242 WeakPolarHBondContact CA-SG 3.38Å; C239-C242 HydrophobicContact CB-CB 3.76Å; C239-C242 WeakPolarHBondContact CB-SG 3.44Å; C239-C242 PolarHBondContact O-N 3.38Å; C239-C242 WeakPolarHBondContact SG-CB 3.47Å; C239-C242 CovalentContact SG-SG 2.01Å; C239-C242 PolarHBondContact SG-SG 3.13Å
240	A	68.9	Low	83.6	Confident	58 Å²	58	66 Å²	66	48%	0.479	37%	0.367	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.4	124.4	173.4	0	0	0	0	0	108.6	K97 C242	K97-A240 PolarHBondContact NZ-O 2.99Å; A240-C242 VanDerWaalsContact C-N 3.34Å; A240-C242 PolarHBondContact O-N 3.4Å
241	D	72.6	Confident	83	Confident	153 Å²	153	66.4 Å²	66.4	82%	0.818	37%	0.37	S	S	*	.	T	Hydrogen-bonded Turn	trans	61.9	31.1	179.9	-46.9	-53.5	0	0	0	115.4	C239 G243	C239-D241 PolarHBondContact O-N 3.16Å; D241-G243 PolarHBondContact O-N 2.82Å
242	C	79.3	Confident	82.4	Confident	44 Å²	44	62.8 Å²	62.8	30%	0.297	36%	0.355	S	S	.	.			trans	-74.5	119.3	173.4	-69.5	0	0	0	0	111.2	C239 A240 Q246	C239-C242 VanDerWaalsContact C-SG 3.58Å; C239-C242 WeakPolarHBondContact CA-SG 3.38Å; C239-C242 HydrophobicContact CB-CB 3.76Å; C239-C242 WeakPolarHBondContact CB-SG 3.44Å; C239-C242 PolarHBondContact O-N 3.38Å; C239-C242 WeakPolarHBondContact SG-CB 3.47Å; C239-C242 CovalentContact SG-SG 2.01Å; C239-C242 PolarHBondContact SG-SG 3.13Å; A240-C242 VanDerWaalsContact C-N 3.34Å; A240-C242 PolarHBondContact O-N 3.4Å; C242-Q246 HydrophobicContact CB-CB 4.05Å
243	G	81.8	Confident	82.2	Confident	28 Å²	28	57.5 Å²	57.5	29%	0.289	33%	0.332	S	S	.	.			trans	-95.6	-168.9	174.4	0	0	0	0	0	112.7	D241 V245 Q246 L247	D241-G243 PolarHBondContact O-N 2.82Å; G243-V245 VanDerWaalsContact C-N 3.28Å; G243-V245 PolarHBondContact O-N 2.93Å; G243-Q246 PolarHBondContact O-N 2.64Å; G243-Q246 PolarHBondContact O-OE1 3.43Å; G243-L247 PolarHBondContact O-N 2.67Å; G243-L247 VanDerWaalsContact O-N 3.17Å
244	P	79.8	Confident	82	Confident	99 Å²	99	58.8 Å²	58.8	64%	0.643	34%	0.34	S	S	*	.	H	α-helix	trans	-61.4	-35.1	-179.2	24.1	-33.3	0	0	0	112.7	L247 E248	P244-L247 PolarHBondContact O-N 3.12Å; P244-E248 WeakPolarHBondContact O-CB 3.26Å; P244-E248 PolarHBondContact O-N 3.36Å
245	V	81.5	Confident	81.6	Confident	68 Å²	68	57.7 Å²	57.7	41%	0.412	33%	0.334	S	S	.	.	H	α-helix	trans	-63.3	-44.6	178.8	-180	0	0	0	0	111.2	K93 G243 L247 E248 Q249	K93-V245 HydrophobicContact CB-CG1 4.49Å; K93-V245 HydrophobicContact CD-CG1 4.04Å; G243-V245 VanDerWaalsContact C-N 3.28Å; G243-V245 PolarHBondContact O-N 2.93Å; V245-L247 VanDerWaalsContact C-N 3.33Å; V245-E248 PolarHBondContact O-N 2.88Å; V245-Q249 VanDerWaalsContact O-CG 3.26Å; V245-Q249 WeakPolarHBondContact O-CG 3.29Å; V245-Q249 PolarHBondContact O-N 2.93Å; V245-Q249 VanDerWaalsContact O-N 3.09Å
246	Q	86.4	Confident	81.2	Confident	37 Å²	37	51.2 Å²	51.2	17%	0.173	31%	0.306	C	S	.	.	H	α-helix	trans	-69.3	-33.9	178.3	-66.2	81	7.3	0	0	111.8	A94 C242 G243 Q249 A250	A94-Q246 HydrophobicContact CB-CB 4.45Å; A94-Q246 HydrophobicContact CB-CG 3.91Å; C242-Q246 HydrophobicContact CB-CB 4.05Å; G243-Q246 PolarHBondContact O-N 2.64Å; G243-Q246 PolarHBondContact O-OE1 3.43Å; Q246-Q249 PolarHBondContact O-N 3.49Å; Q246-A250 WeakPolarHBondContact O-CB 3.48Å; Q246-A250 PolarHBondContact O-N 3.5Å
247	L	81.7	Confident	81.2	Confident	99 Å²	99	46.4 Å²	46.4	52%	0.518	28%	0.281	S	S	.	.	H	α-helix	trans	-67.3	-41.6	175.3	-175	65.9	0	0	0	111.6	G243 P244 V245 Q249 A250 V251	G243-L247 PolarHBondContact O-N 2.67Å; G243-L247 VanDerWaalsContact O-N 3.17Å; P244-L247 PolarHBondContact O-N 3.12Å; V245-L247 VanDerWaalsContact C-N 3.33Å; L247-Q249 VanDerWaalsContact C-N 3.31Å; L247-Q249 PolarHBondContact O-N 3.08Å; L247-A250 WeakPolarHBondContact O-CB 3.15Å; L247-A250 PolarHBondContact O-N 3.35Å; L247-V251 PolarHBondContact O-N 2.95Å
248	E	79.9	Confident	81.5	Confident	89 Å²	89	42 Å²	42	42%	0.416	25%	0.252	S	S	.	.	H	α-helix	trans	-59.3	-43.6	174.4	-176.6	176	-169	0	0	111.1	P244 V245 V251 G252 F488	P244-E248 WeakPolarHBondContact O-CB 3.26Å; P244-E248 PolarHBondContact O-N 3.36Å; V245-E248 PolarHBondContact O-N 2.88Å; E248-V251 PolarHBondContact O-N 3.28Å; E248-G252 PolarHBondContact O-N 3.44Å; E248-F488 HydrophobicContact CG-CE1 4.24Å; E248-F488 HydrophobicContact CG-CZ 4.08Å
249	Q	85.5	Confident	82	Confident	13 Å²	13	39.2 Å²	39.2	6%	0.061	24%	0.241	C	C	.	.	H	α-helix	trans	-64.8	-39.6	174.5	-66	-64.3	-47.4	0	0	112.4	Q89 K93 L98 V245 Q246 L247 V251 G252 I253	Q89-Q249 VanDerWaalsContact OE1-NE2 3.15Å; K93-Q249 HydrophobicContact CB-CG 4.32Å; K93-Q249 HydrophobicContact CD-CG 3.82Å; K93-Q249 VanDerWaalsContact NZ-NE2 3.15Å; L98-Q249 HydrophobicContact CD1-CB 3.74Å; V245-Q249 VanDerWaalsContact O-CG 3.26Å; V245-Q249 WeakPolarHBondContact O-CG 3.29Å; V245-Q249 PolarHBondContact O-N 2.93Å; V245-Q249 VanDerWaalsContact O-N 3.09Å; Q246-Q249 PolarHBondContact O-N 3.49Å; L247-Q249 VanDerWaalsContact C-N 3.31Å; L247-Q249 PolarHBondContact O-N 3.08Å; Q249-V251 VanDerWaalsContact C-N 3.27Å; Q249-V251 PolarHBondContact O-N 2.95Å; Q249-G252 PolarHBondContact O-N 3.35Å; Q249-I253 VanDerWaalsContact O-CG1 3.32Å; Q249-I253 WeakPolarHBondContact O-CG1 3.24Å; Q249-I253 PolarHBondContact O-N 2.9Å
250	A	85.3	Confident	82.8	Confident	13 Å²	13	36.5 Å²	36.5	11%	0.107	22%	0.223	C	C	.	.	H	α-helix	trans	-60.3	-38.9	175.1	0	0	0	0	0	112	L98 V101 Q246 L247 V254	L98-A250 HydrophobicContact CD1-CB 4.48Å; L98-A250 HydrophobicContact CD2-CB 3.89Å; V101-A250 HydrophobicContact CG1-CB 4.36Å; V101-A250 HydrophobicContact CG2-CB 4.33Å; Q246-A250 WeakPolarHBondContact O-CB 3.48Å; Q246-A250 PolarHBondContact O-N 3.5Å; L247-A250 WeakPolarHBondContact O-CB 3.15Å; L247-A250 PolarHBondContact O-N 3.35Å; A250-V254 WeakPolarHBondContact O-CG2 3.48Å; A250-V254 PolarHBondContact O-N 3Å
251	V	80.4	Confident	83.9	Confident	14 Å²	14	33.7 Å²	33.7	9%	0.085	20%	0.2	C	C	.	.	H	α-helix	trans	-71.4	-40.7	174.6	172.7	0	0	0	0	111.5	L247 E248 Q249 I253 V254 G255 I484 F488	L247-V251 PolarHBondContact O-N 2.95Å; E248-V251 PolarHBondContact O-N 3.28Å; Q249-V251 VanDerWaalsContact C-N 3.27Å; Q249-V251 PolarHBondContact O-N 2.95Å; V251-I253 VanDerWaalsContact C-N 3.29Å; V251-I253 PolarHBondContact O-N 2.92Å; V251-V254 PolarHBondContact O-N 3.43Å; V251-V254 VanDerWaalsContact O-N 3.09Å; V251-G255 PolarHBondContact O-N 2.82Å; V251-I484 HydrophobicContact CB-CG2 4Å; V251-I484 HydrophobicContact CG1-CG2 3.26Å; V251-I484 HydrophobicContact CG2-CD1 4.37Å; V251-I484 HydrophobicContact CG2-CG1 4.42Å; V251-I484 HydrophobicContact CG2-CG2 3.51Å; V251-F488 HydrophobicContact CB-CE2 3.64Å; V251-F488 HydrophobicContact CB-CZ 3.99Å; V251-F488 HydrophobicContact CG1-CD2 4.03Å; V251-F488 HydrophobicContact CG1-CE2 3.33Å; V251-F488 HydrophobicContact CG1-CZ 3.86Å; V251-F488 HydrophobicContact CG2-CE2 3.89Å
252	G	82.1	Confident	84.9	Confident	17 Å²	17	26.4 Å²	26.4	18%	0.175	16%	0.161	C	C	.	.	H	α-helix	trans	-51.8	-48	172.3	0	0	0	0	0	111.8	S86 E248 Q249 V254 G255 A256	S86-G252 PolarHBondContact OG-O 2.97Å; E248-G252 PolarHBondContact O-N 3.44Å; Q249-G252 PolarHBondContact O-N 3.35Å; G252-V254 PolarHBondContact O-N 3.24Å; G252-G255 PolarHBondContact O-N 3.09Å; G252-A256 VanDerWaalsContact O-CB 3.26Å; G252-A256 WeakPolarHBondContact O-CB 3.36Å; G252-A256 PolarHBondContact O-N 3.21Å
253	I	87.6	Confident	85.6	Confident	0 Å²	0	24.4 Å²	24.4	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-57.8	-46.2	175.9	-64.9	165.8	0	0	0	111.1	S86 L98 V101 L102 Q249 V251 G255 A256 V257	S86-I253 PolarHBondContact OG-N 2.74Å; L98-I253 HydrophobicContact CB-CD1 3.76Å; L98-I253 HydrophobicContact CD1-CD1 4.13Å; V101-I253 HydrophobicContact CG1-CB 4.4Å; V101-I253 HydrophobicContact CG1-CG2 4.28Å; L102-I253 HydrophobicContact CB-CG2 4.07Å; L102-I253 HydrophobicContact CD1-CG2 4.06Å; Q249-I253 VanDerWaalsContact O-CG1 3.32Å; Q249-I253 WeakPolarHBondContact O-CG1 3.24Å; Q249-I253 PolarHBondContact O-N 2.9Å; V251-I253 VanDerWaalsContact C-N 3.29Å; V251-I253 PolarHBondContact O-N 2.92Å; I253-G255 PolarHBondContact O-N 3.33Å; I253-A256 PolarHBondContact O-N 3.39Å; I253-V257 HydrophobicContact CG2-CG2 4.02Å; I253-V257 VanDerWaalsContact O-CB 3.22Å; I253-V257 WeakPolarHBondContact O-CB 3.46Å; I253-V257 WeakPolarHBondContact O-CG2 3.32Å; I253-V257 PolarHBondContact O-N 3.47Å
254	V	85.1	Confident	86.2	Confident	27 Å²	27	23.1 Å²	23.1	16%	0.164	13%	0.134	C	C	.	.	H	α-helix	trans	-61.7	-45.4	179.6	176	0	0	0	0	111	V101 S105 A250 V251 G252 I258	V101-V254 HydrophobicContact CG1-CG2 4.12Å; S105-V254 VanDerWaalsContact OG-CG2 3.31Å; S105-V254 WeakPolarHBondContact OG-CG2 3.49Å; A250-V254 WeakPolarHBondContact O-CG2 3.48Å; A250-V254 PolarHBondContact O-N 3Å; V251-V254 PolarHBondContact O-N 3.43Å; V251-V254 VanDerWaalsContact O-N 3.09Å; G252-V254 PolarHBondContact O-N 3.24Å; V254-I258 HydrophobicContact CG1-CD1 4.27Å; V254-I258 WeakPolarHBondContact O-CB 3.32Å; V254-I258 PolarHBondContact O-N 3.3Å
255	G	80.7	Confident	86.9	Confident	0 Å²	0	18.5 Å²	18.5	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-67.3	-37.2	179.8	0	0	0	0	0	113.5	V251 G252 I253	V251-G255 PolarHBondContact O-N 2.82Å; G252-G255 PolarHBondContact O-N 3.09Å; I253-G255 PolarHBondContact O-N 3.33Å
256	A	84.7	Confident	87.5	Confident	1 Å²	1	15.2 Å²	15.2	1%	0.008	8%	0.084	C	C	.	.	H	α-helix	trans	-76.4	-37.6	179.1	0	0	0	0	0	112.5	N83 G252 I253	N83-A256 HydrophobicContact CB-CB 4.4Å; N83-A256 PolarHBondContact ND2-O 3.46Å; G252-A256 VanDerWaalsContact O-CB 3.26Å; G252-A256 WeakPolarHBondContact O-CB 3.36Å; G252-A256 PolarHBondContact O-N 3.21Å; I253-A256 PolarHBondContact O-N 3.39Å
257	V	88.2	Confident	87.9	Confident	0 Å²	0	13.5 Å²	13.5	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-73.6	-41.9	178.3	171.7	0	0	0	0	111.3	Y78 L102 I253 M259	Y78-V257 HydrophobicContact CD1-CG1 3.81Å; Y78-V257 WeakPolarHBondContact CD1-O 3.19Å; Y78-V257 HydrophobicContact CE1-CG1 3.54Å; Y78-V257 WeakPolarHBondContact CE1-O 3.39Å; L102-V257 HydrophobicContact CD1-CG2 3.7Å; I253-V257 HydrophobicContact CG2-CG2 4.02Å; I253-V257 VanDerWaalsContact O-CB 3.22Å; I253-V257 WeakPolarHBondContact O-CB 3.46Å; I253-V257 WeakPolarHBondContact O-CG2 3.32Å; I253-V257 PolarHBondContact O-N 3.47Å; V257-M259 PolarHBondContact O-N 3.25Å
258	I	88.4	Confident	88.5	Confident	4 Å²	4	8.8 Å²	8.8	2%	0.021	5%	0.051	C	C	.	.	S	Bend	trans	-99.5	93.6	-179.1	-50.4	176.2	0	0	0	107.8	I108 L112 V254 L444 L448	I108-I258 HydrophobicContact CB-CD1 4.26Å; I108-I258 HydrophobicContact CG2-CD1 3.71Å; L112-I258 HydrophobicContact CD1-CD1 4.11Å; L112-I258 HydrophobicContact CD1-CG2 3.64Å; V254-I258 HydrophobicContact CG1-CD1 4.27Å; V254-I258 WeakPolarHBondContact O-CB 3.32Å; V254-I258 PolarHBondContact O-N 3.3Å; I258-L444 HydrophobicContact CB-CD2 3.99Å; I258-L444 HydrophobicContact CG2-CD2 3.61Å; I258-L444 WeakPolarHBondContact O-CD2 3.35Å; I258-L448 HydrophobicContact CG2-CD2 4.37Å
259	M	89.3	Confident	89	Confident	2 Å²	2	4.7 Å²	4.7	1%	0.01	3%	0.032	C	C	.	.			trans	-88.7	129.9	178.3	-65.2	-172.9	111.4	0	0	112.1	A77 D80 S154 V257 H261 N262	A77-M259 HydrophobicContact CB-SD 3.81Å; D80-M259 WeakPolarHBondContact OD2-CE 3.46Å; S154-M259 WeakPolarHBondContact OG-CE 3.32Å; V257-M259 PolarHBondContact O-N 3.25Å; M259-H261 VanDerWaalsContact CE-CE1 3.4Å; M259-H261 WeakPolarHBondContact CE-CE1 3.45Å; M259-H261 PolarHBondContact O-N 2.98Å; M259-H261 PolarHBondContact SD-CE1 3.42Å; M259-N262 HydrophobicContact CB-CB 3.95Å; M259-N262 PolarHBondContact O-N 3.14Å
260	P	90.2	Very high	89.3	Confident	0 Å²	0	4.2 Å²	4.2	0%	0	3%	0.03	C	C	.	.	H	α-helix	trans	-61.9	-47.1	-177.4	-12.9	20.1	0	0	0	112.4	I147 A150 N262 I263 Y264 Q443 L444 A447	I147-P260 HydrophobicContact CD1-CB 4.32Å; A150-P260 HydrophobicContact CB-CG 4.38Å; P260-N262 PolarHBondContact O-N 3.45Å; P260-I263 WeakPolarHBondContact O-CB 3.5Å; P260-I263 PolarHBondContact O-N 3.28Å; P260-Y264 WeakPolarHBondContact O-CD2 3.34Å; P260-Q443 HydrophobicContact CB-CB 4.47Å; P260-Q443 HydrophobicContact CG-CB 3.75Å; P260-L444 HydrophobicContact CG-CD2 4.08Å; P260-L444 HydrophobicContact CG-CG 4.35Å; P260-A447 HydrophobicContact CB-CB 3.69Å; P260-A447 WeakPolarHBondContact O-CB 3.4Å
261	H	91.5	Very high	89.6	Confident	0 Å²	0	5.2 Å²	5.2	0%	0	3%	0.032	C	C	.	.	H	α-helix	trans	-63.9	-29.5	-177.3	69.1	-99.8	0	0	0	112.1	I151 S154 M259 I263 Y264 L265	I151-H261 HydrophobicContact CD1-CB 4.41Å; I151-H261 HydrophobicContact CG1-CB 3.57Å; S154-H261 PolarHBondContact OG-CE1 2.91Å; M259-H261 VanDerWaalsContact CE-CE1 3.4Å; M259-H261 WeakPolarHBondContact CE-CE1 3.45Å; M259-H261 PolarHBondContact O-N 2.98Å; M259-H261 PolarHBondContact SD-CE1 3.42Å; H261-I263 VanDerWaalsContact C-N 3.3Å; H261-I263 PolarHBondContact O-N 2.89Å; H261-Y264 WeakPolarHBondContact O-CB 3.32Å; H261-Y264 PolarHBondContact O-N 3.44Å; H261-Y264 VanDerWaalsContact O-N 3.15Å; H261-L265 PolarHBondContact O-N 3Å
262	N	92.6	Very high	89.9	Confident	0 Å²	0	4.6 Å²	4.6	0%	0	3%	0.028	C	C	.	.	H	α-helix	trans	-69.8	-27.5	-179.1	-163.8	22.6	0	0	0	112.5	M74 A77 Y78 Q113 M259 P260 L265 H266	M74-N262 WeakPolarHBondContact CG-OD1 3.48Å; M74-N262 PolarHBondContact O-ND2 3.34Å; M74-N262 PolarHBondContact O-OD1 3.29Å; A77-N262 HydrophobicContact CB-CB 4Å; A77-N262 WeakPolarHBondContact CB-ND2 3.01Å; Y78-N262 VanDerWaalsContact CE2-ND2 3.3Å; Y78-N262 WeakPolarHBondContact CE2-ND2 3.1Å; Q113-N262 PolarHBondContact NE2-ND2 3.12Å; M259-N262 HydrophobicContact CB-CB 3.95Å; M259-N262 PolarHBondContact O-N 3.14Å; P260-N262 PolarHBondContact O-N 3.45Å; N262-L265 PolarHBondContact O-N 3.14Å; N262-H266 WeakPolarHBondContact O-CB 3.34Å; N262-H266 PolarHBondContact O-N 3.46Å
263	I	94.6	Very high	90.2	Very high	1 Å²	1	4.1 Å²	4.1	1%	0.005	2%	0.021	C	C	.	.	H	α-helix	trans	-65.3	-41.4	172	-62.2	179.3	0	0	0	110.2	A116 L127 P260 H261 S267 A447 L448 I451	A116-I263 HydrophobicContact CB-CG2 3.96Å; A116-I263 WeakPolarHBondContact CB-O 3.37Å; L127-I263 HydrophobicContact CD2-CG2 3.9Å; P260-I263 WeakPolarHBondContact O-CB 3.5Å; P260-I263 PolarHBondContact O-N 3.28Å; H261-I263 VanDerWaalsContact C-N 3.3Å; H261-I263 PolarHBondContact O-N 2.89Å; I263-S267 PolarHBondContact O-N 2.88Å; I263-S267 PolarHBondContact O-OG 3.44Å; I263-A447 HydrophobicContact CB-CB 4.31Å; I263-A447 HydrophobicContact CD1-CB 3.91Å; I263-L448 HydrophobicContact CD1-CD2 3.64Å; I263-I451 HydrophobicContact CG2-CB 4.11Å; I263-I451 HydrophobicContact CG2-CG1 4.15Å; I263-I451 HydrophobicContact CG2-CG2 4.24Å
264	Y	94.9	Very high	90.1	Very high	2 Å²	2	8.5 Å²	8.5	1%	0.008	4%	0.041	C	C	.	.	H	α-helix	trans	-66.4	-46.2	174.6	-70.2	-92.4	0	0	0	110.8	L127 A128 I147 P260 H261 S267 A268 V391 F395 F446 A447	L127-Y264 HydrophobicContact CB-CD1 3.77Å; L127-Y264 HydrophobicContact CB-CE1 4Å; L127-Y264 HydrophobicContact CB-CG 4.49Å; L127-Y264 HydrophobicContact CD2-CD1 3.84Å; L127-Y264 HydrophobicContact CD2-CD2 4.24Å; L127-Y264 HydrophobicContact CD2-CE1 3.59Å; L127-Y264 HydrophobicContact CD2-CE2 4Å; L127-Y264 HydrophobicContact CD2-CG 4.15Å; L127-Y264 HydrophobicContact CG-CD1 3.82Å; L127-Y264 HydrophobicContact CG-CE1 3.52Å; A128-Y264 HydrophobicContact CB-CD1 3.96Å; A128-Y264 HydrophobicContact CB-CE1 4.29Å; I147-Y264 HydrophobicContact CD1-CD2 4.28Å; I147-Y264 HydrophobicContact CD1-CE2 3.45Å; I147-Y264 VanDerWaalsContact CD1-CE2 3.45Å; I147-Y264 HydrophobicContact CG1-CD2 4.4Å; I147-Y264 HydrophobicContact CG1-CE2 3.64Å; I147-Y264 HydrophobicContact CG2-CD2 4Å; I147-Y264 HydrophobicContact CG2-CE2 4.09Å; I147-Y264 HydrophobicContact CG2-CG 4.49Å; P260-Y264 WeakPolarHBondContact O-CD2 3.34Å; H261-Y264 WeakPolarHBondContact O-CB 3.32Å; H261-Y264 PolarHBondContact O-N 3.44Å; H261-Y264 VanDerWaalsContact O-N 3.15Å; Y264-S267 PolarHBondContact O-N 2.6Å; Y264-S267 PolarHBondContact O-OG 3.27Å; Y264-A268 PolarHBondContact O-N 3.22Å; Y264-V391 HydrophobicContact CD1-CG2 4.27Å; Y264-V391 HydrophobicContact CG-CG2 4.06Å; Y264-F395 HydrophobicContact CD1-CE2 4.14Å; Y264-F395 AromaticContact CE1-CE2 3.55Å; Y264-F395 HydrophobicContact CE1-CE2 3.55Å; Y264-F395 AromaticContact CE1-CZ 3.69Å; Y264-F395 HydrophobicContact CE1-CZ 3.69Å; Y264-F446 PolarHBondContact OH-O 3.13Å; Y264-A447 HydrophobicContact CD2-CB 4.33Å; Y264-A447 HydrophobicContact CE2-CB 3.72Å
265	L	93.4	Very high	90.2	Very high	1 Å²	1	8.4 Å²	8.4	1%	0.005	4%	0.041	C	C	.	.	H	α-helix	trans	-56.1	-54.2	178.8	-179.1	60.6	0	0	0	112.1	H261 N262 S267 A268 L269 T383 S387 F390	H261-L265 PolarHBondContact O-N 3Å; N262-L265 PolarHBondContact O-N 3.14Å; L265-S267 VanDerWaalsContact C-N 3.3Å; L265-S267 PolarHBondContact O-N 3.45Å; L265-A268 WeakPolarHBondContact O-CA 3.44Å; L265-A268 WeakPolarHBondContact O-CB 3.18Å; L265-A268 PolarHBondContact O-N 3.35Å; L265-L269 HydrophobicContact CD1-CD1 4.04Å; L265-L269 HydrophobicContact CD1-CD2 4.28Å; L265-L269 HydrophobicContact CD1-CG 3.96Å; L265-L269 HydrophobicContact CD2-CD1 4.23Å; L265-L269 HydrophobicContact CG-CD1 3.73Å; L265-L269 HydrophobicContact CG-CG 4.09Å; L265-L269 WeakPolarHBondContact O-CG 3.41Å; L265-L269 PolarHBondContact O-N 3.45Å; L265-T383 HydrophobicContact CD2-CG2 4.32Å; L265-S387 WeakPolarHBondContact CB-OG 3.37Å; L265-F390 HydrophobicContact CD1-CD2 4.07Å; L265-F390 HydrophobicContact CD1-CE2 4.12Å
266	H	95	Very high	90.5	Very high	0 Å²	0	11.9 Å²	11.9	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-64.1	-36.9	-175.6	-168.8	-165.4	0	0	0	112.3	M74 Q113 A116 N262 A268 L269 V270 S294	M74-H266 HydrophobicContact CB-CB 4.12Å; M74-H266 HydrophobicContact CG-CB 3.7Å; Q113-H266 PolarHBondContact O-ND1 2.94Å; Q113-H266 PolarHBondContact OE1-ND1 3.48Å; A116-H266 HydrophobicContact CB-CB 4.44Å; N262-H266 WeakPolarHBondContact O-CB 3.34Å; N262-H266 PolarHBondContact O-N 3.46Å; H266-A268 PolarHBondContact O-N 2.98Å; H266-L269 PolarHBondContact O-N 2.68Å; H266-V270 PolarHBondContact O-N 2.75Å; H266-S294 PolarHBondContact CE1-OG 3.43Å; H266-S294 PolarHBondContact NE2-OG 2.93Å
267	S	95.4	Very high	90.6	Very high	0 Å²	0	17.2 Å²	17.2	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-61.5	-25.1	173.9	75.9	0	0	0	0	113.3	A116 G120 H126 L127 I263 Y264 L265 V270	A116-S267 WeakPolarHBondContact O-CA 3.22Å; A116-S267 WeakPolarHBondContact O-CB 3.38Å; G120-S267 WeakPolarHBondContact CA-O 3.46Å; H126-S267 WeakPolarHBondContact CB-OG 3.12Å; L127-S267 PolarHBondContact N-OG 3.42Å; I263-S267 PolarHBondContact O-N 2.88Å; I263-S267 PolarHBondContact O-OG 3.44Å; Y264-S267 PolarHBondContact O-N 2.6Å; Y264-S267 PolarHBondContact O-OG 3.27Å; L265-S267 VanDerWaalsContact C-N 3.3Å; L265-S267 PolarHBondContact O-N 3.45Å; S267-V270 WeakPolarHBondContact O-CG2 3.37Å
268	A	92.7	Very high	90.5	Very high	0 Å²	0	26.5 Å²	26.5	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-88.4	-41	174.8	0	0	0	0	0	112.9	H126 Y264 L265 H266 V270 K271 F390	H126-A268 HydrophobicContact CB-CB 3.69Å; Y264-A268 PolarHBondContact O-N 3.22Å; L265-A268 WeakPolarHBondContact O-CA 3.44Å; L265-A268 WeakPolarHBondContact O-CB 3.18Å; L265-A268 PolarHBondContact O-N 3.35Å; H266-A268 PolarHBondContact O-N 2.98Å; A268-V270 VanDerWaalsContact C-N 3.27Å; A268-V270 PolarHBondContact O-N 3.41Å; A268-K271 VanDerWaalsContact O-CB 3.27Å; A268-K271 WeakPolarHBondContact O-CB 3.29Å; A268-K271 PolarHBondContact O-N 3.28Å; A268-F390 HydrophobicContact CB-CB 4.02Å; A268-F390 HydrophobicContact CB-CD1 3.6Å; A268-F390 HydrophobicContact CB-CD2 3.5Å; A268-F390 VanDerWaalsContact CB-CD2 3.5Å; A268-F390 HydrophobicContact CB-CE1 3.85Å; A268-F390 HydrophobicContact CB-CE2 3.76Å; A268-F390 HydrophobicContact CB-CG 3.42Å; A268-F390 VanDerWaalsContact CB-CG 3.42Å; A268-F390 HydrophobicContact CB-CZ 3.93Å
269	L	91.5	Very high	90.6	Very high	4 Å²	4	29 Å²	29	2%	0.021	13%	0.133	C	C	.	.	H	α-helix	trans	-61.7	-33.5	-177.5	-70.4	175.1	0	0	0	113	P70 L73 L265 H266 K271 S272	P70-L269 HydrophobicContact CB-CB 3.85Å; P70-L269 HydrophobicContact CG-CB 4.46Å; P70-L269 WeakPolarHBondContact CG-O 3.26Å; L73-L269 HydrophobicContact CB-CD1 3.65Å; L73-L269 HydrophobicContact CD2-CD1 4.37Å; L73-L269 HydrophobicContact CD2-CD2 3.96Å; L265-L269 HydrophobicContact CD1-CD1 4.04Å; L265-L269 HydrophobicContact CD1-CD2 4.28Å; L265-L269 HydrophobicContact CD1-CG 3.96Å; L265-L269 HydrophobicContact CD2-CD1 4.23Å; L265-L269 HydrophobicContact CG-CD1 3.73Å; L265-L269 HydrophobicContact CG-CG 4.09Å; L265-L269 WeakPolarHBondContact O-CG 3.41Å; L265-L269 PolarHBondContact O-N 3.45Å; H266-L269 PolarHBondContact O-N 2.68Å; L269-K271 PolarHBondContact O-N 3.06Å; L269-S272 WeakPolarHBondContact O-CB 3.42Å; L269-S272 PolarHBondContact O-N 3.46Å; L269-S272 VanDerWaalsContact O-N 3.09Å; L269-S272 PolarHBondContact O-OG 3.07Å
270	V	92.6	Very high	90.6	Very high	3 Å²	3	34.9 Å²	34.9	2%	0.018	16%	0.159	C	C	.	.	G	3₁₀ helix	trans	-64.9	-20.3	176.6	-63.5	0	0	0	0	113.3	P70 A117 V121 H266 S267 A268 S272 F290	P70-V270 HydrophobicContact CB-CG1 4.47Å; A117-V270 HydrophobicContact CB-CG1 3.88Å; V121-V270 HydrophobicContact CG2-CB 3.98Å; V121-V270 HydrophobicContact CG2-CG2 4.04Å; H266-V270 PolarHBondContact O-N 2.75Å; S267-V270 WeakPolarHBondContact O-CG2 3.37Å; A268-V270 VanDerWaalsContact C-N 3.27Å; A268-V270 PolarHBondContact O-N 3.41Å; V270-S272 PolarHBondContact O-N 3.16Å; V270-F290 HydrophobicContact CB-CD2 4.45Å; V270-F290 HydrophobicContact CB-CE1 4.13Å; V270-F290 HydrophobicContact CB-CE2 4.03Å; V270-F290 HydrophobicContact CB-CZ 3.83Å; V270-F290 HydrophobicContact CG1-CD1 3.89Å; V270-F290 HydrophobicContact CG1-CD2 4.32Å; V270-F290 HydrophobicContact CG1-CE1 3.89Å; V270-F290 HydrophobicContact CG1-CE2 4.31Å; V270-F290 HydrophobicContact CG1-CG 4.1Å; V270-F290 HydrophobicContact CG1-CZ 4.08Å
271	K	89.8	Confident	90.5	Very high	34 Å²	34	43.1 Å²	43.1	15%	0.148	19%	0.194	C	C	.	.	G	3₁₀ helix	trans	-70	-13.1	174.2	-63.6	172	61.6	175	0	112.9	G124 H126 E129 A268 L269 R273	G124-K271 WeakPolarHBondContact O-CE 3.28Å; G124-K271 PolarHBondContact O-NZ 3.3Å; H126-K271 HydrophobicContact CB-CD 4.32Å; E129-K271 VanDerWaalsContact CD-NZ 3.34Å; E129-K271 IonicContact OE1-NZ 2.79Å; E129-K271 PolarHBondContact OE1-NZ 2.98Å; E129-K271 IonicContact OE2-NZ 2.73Å; E129-K271 PolarHBondContact OE2-NZ 3.45Å; A268-K271 VanDerWaalsContact O-CB 3.27Å; A268-K271 WeakPolarHBondContact O-CB 3.29Å; A268-K271 PolarHBondContact O-N 3.28Å; L269-K271 PolarHBondContact O-N 3.06Å; K271-R273 PolarHBondContact O-N 3.27Å
272	S	87.2	Confident	90.4	Very high	1 Å²	1	46.2 Å²	46.2	1%	0.007	21%	0.209	C	C	.	.	G	3₁₀ helix	trans	-66.8	-17.3	177.6	67.1	0	0	0	0	114.3	F45 V49 L269 V270	F45-S272 VanDerWaalsContact CZ-CB 3.44Å; V49-S272 PolarHBondContact N-O 3.32Å; V49-S272 VanDerWaalsContact N-O 3.12Å; L269-S272 WeakPolarHBondContact O-CB 3.42Å; L269-S272 PolarHBondContact O-N 3.46Å; L269-S272 VanDerWaalsContact O-N 3.09Å; L269-S272 PolarHBondContact O-OG 3.07Å; V270-S272 PolarHBondContact O-N 3.16Å
273	R	89.1	Confident	90.3	Very high	7 Å²	7	46.4 Å²	46.4	3%	0.026	21%	0.21	C	C	.	.	B	Isolated β-bridge	trans	-100.6	135	178.4	-55.4	-53.5	-170.5	-107.2	11.3	109.6	A66 F67 T68 L198 E202 K271 V275 F290	A66-R273 PolarHBondContact O-NE 3.21Å; F67-R273 HydrophobicContact CD1-CB 4.31Å; F67-R273 HydrophobicContact CD1-CG 4.1Å; F67-R273 HydrophobicContact CE1-CB 4.26Å; T68-R273 PolarHBondContact O-NH2 2.73Å; L198-R273 VanDerWaalsContact CD2-NH1 3.34Å; E202-R273 IonicContact OE1-CZ 3.47Å; E202-R273 VanDerWaalsContact OE1-CZ 3.27Å; E202-R273 IonicContact OE1-NH1 2.75Å; E202-R273 PolarHBondContact OE1-NH1 2.76Å; E202-R273 IonicContact OE1-NH2 3.38Å; E202-R273 PolarHBondContact OE1-NH2 2.92Å; E202-R273 IonicContact OE2-NH2 2.73Å; E202-R273 PolarHBondContact OE2-NH2 3.15Å; K271-R273 PolarHBondContact O-N 3.27Å; R273-V275 PolarHBondContact O-N 3.48Å; R273-F290 HydrophobicContact CB-CZ 3.95Å; R273-F290 HydrophobicContact CG-CE1 4.09Å; R273-F290 HydrophobicContact CG-CZ 3.69Å
274	E	85.1	Confident	90.2	Very high	91 Å²	91	53.6 Å²	53.6	43%	0.425	24%	0.241	S	C	.	.			trans	-73.6	118.6	177.1	-61.1	-166.7	146.3	0	0	110.3	R48 V49 I51	R48-E274 HydrophobicContact CB-CG 3.23Å; R48-E274 HydrophobicContact CG-CG 4.16Å; V49-E274 PolarHBondContact O-N 3.38Å; I51-E274 WeakPolarHBondContact CD1-O 3.48Å; I51-E274 WeakPolarHBondContact CG1-O 3.36Å
275	V	86.8	Confident	90	Very high	25 Å²	25	56 Å²	56	15%	0.152	25%	0.252	C	S	.	.			trans	-131.2	125.3	176.9	-179.5	0	0	0	0	107.9	I51 F67 R273 R277 E282 V283 A286	I51-V275 HydrophobicContact CD1-CG2 4.11Å; F67-V275 HydrophobicContact CE1-CG2 4.4Å; R273-V275 PolarHBondContact O-N 3.48Å; V275-R277 PolarHBondContact O-N 3.41Å; V275-R277 VanDerWaalsContact O-N 3.15Å; V275-E282 HydrophobicContact CG1-CB 4.41Å; V275-V283 HydrophobicContact CG1-CG2 4.31Å; V275-A286 HydrophobicContact CG1-CB 4.03Å; V275-A286 HydrophobicContact CG2-CB 3.83Å
276	D	87.3	Confident	89.9	Confident	74 Å²	74	56 Å²	56	40%	0.396	25%	0.253	S	S	.	.			trans	-73.4	108	171.9	-175.9	8.2	0	0	0	110	K278 N279 E282	D276-K278 VanDerWaalsContact C-N 3.26Å; D276-K278 PolarHBondContact O-N 3.12Å; D276-K278 VanDerWaalsContact OD1-CB 3.31Å; D276-K278 WeakPolarHBondContact OD1-CB 3.4Å; D276-K278 PolarHBondContact OD1-N 3.39Å; D276-N279 HydrophobicContact CB-CB 4.46Å; D276-N279 PolarHBondContact O-N 2.97Å; D276-E282 VanDerWaalsContact CB-OE2 3.3Å; D276-E282 WeakPolarHBondContact CB-OE2 3.34Å; D276-E282 PolarHBondContact N-OE2 3.38Å
277	R	86.7	Confident	89.8	Confident	112 Å²	112	57 Å²	57	42%	0.423	26%	0.258	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.8	-17	-178.6	-58.8	170.5	-159.6	151.4	-0.1	112.4	V275 N279	V275-R277 PolarHBondContact O-N 3.41Å; V275-R277 VanDerWaalsContact O-N 3.15Å; R277-N279 VanDerWaalsContact C-N 3.28Å
278	K	86.9	Confident	89.7	Confident	195 Å²	195	61.1 Å²	61.1	85%	0.848	28%	0.276	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.3	-30	173.9	-60.3	179.9	-178.8	178.3	0	110.7	D276	D276-K278 VanDerWaalsContact C-N 3.26Å; D276-K278 PolarHBondContact O-N 3.12Å; D276-K278 VanDerWaalsContact OD1-CB 3.31Å; D276-K278 WeakPolarHBondContact OD1-CB 3.4Å; D276-K278 PolarHBondContact OD1-N 3.39Å
279	N	89.3	Confident	89.8	Confident	57 Å²	57	61.1 Å²	61.1	31%	0.305	28%	0.276	S	S	.	.			trans	-92.2	103.2	179.2	-170.5	-5	0	0	0	112.1	D276 R277 K281 E282 V283	D276-N279 HydrophobicContact CB-CB 4.46Å; D276-N279 PolarHBondContact O-N 2.97Å; R277-N279 VanDerWaalsContact C-N 3.28Å; N279-K281 PolarHBondContact O-N 2.88Å; N279-K281 WeakPolarHBondContact OD1-CB 3.45Å; N279-K281 PolarHBondContact OD1-N 3.39Å; N279-K281 VanDerWaalsContact OD1-N 3.14Å; N279-E282 HydrophobicContact CB-CB 4.26Å; N279-E282 HydrophobicContact CB-CG 4.27Å; N279-E282 PolarHBondContact ND2-OE1 3.23Å; N279-E282 PolarHBondContact O-N 3.41Å; N279-V283 PolarHBondContact O-N 3.27Å
280	K	89.2	Confident	89.9	Confident	126 Å²	126	61 Å²	61	55%	0.548	28%	0.275	S	S	.	.	H	α-helix	trans	-56.3	-28.5	178.6	-62.5	-177.7	-174.4	177.8	0	113.6	K284 D463 F464	K280-K284 WeakPolarHBondContact O-CB 3.44Å; K280-K284 PolarHBondContact O-N 3.48Å; K280-K284 VanDerWaalsContact O-N 3.12Å; K280-D463 WeakPolarHBondContact CE-OD2 3.34Å; K280-D463 IonicContact NZ-OD2 3.48Å; K280-D463 PolarHBondContact NZ-OD2 2.94Å; K280-F464 HydrophobicContact CB-CZ 4.36Å
281	K	88.9	Confident	90.1	Very high	172 Å²	172	64 Å²	64	75%	0.748	29%	0.288	S	S	*	.	H	α-helix	trans	-69.4	-41.2	178.8	-67.3	-179.9	-179.3	174.4	0	111.4	N279 K284 E285	N279-K281 PolarHBondContact O-N 2.88Å; N279-K281 WeakPolarHBondContact OD1-CB 3.45Å; N279-K281 PolarHBondContact OD1-N 3.39Å; N279-K281 VanDerWaalsContact OD1-N 3.14Å; K281-K284 PolarHBondContact O-N 2.81Å; K281-E285 WeakPolarHBondContact O-CB 3.4Å; K281-E285 PolarHBondContact O-N 3.03Å
282	E	88.8	Confident	90.3	Very high	66 Å²	66	64.5 Å²	64.5	31%	0.308	29%	0.292	S	S	.	.	H	α-helix	trans	-68.6	-42.8	178.3	-75.9	176.4	-133.7	0	0	111.8	V275 D276 N279 K284 E285 A286	V275-E282 HydrophobicContact CG1-CB 4.41Å; D276-E282 VanDerWaalsContact CB-OE2 3.3Å; D276-E282 WeakPolarHBondContact CB-OE2 3.34Å; D276-E282 PolarHBondContact N-OE2 3.38Å; N279-E282 HydrophobicContact CB-CB 4.26Å; N279-E282 HydrophobicContact CB-CG 4.27Å; N279-E282 PolarHBondContact ND2-OE1 3.23Å; N279-E282 PolarHBondContact O-N 3.41Å; E282-K284 VanDerWaalsContact C-N 3.28Å; E282-K284 PolarHBondContact O-N 2.94Å; E282-E285 PolarHBondContact O-N 3.4Å; E282-E285 VanDerWaalsContact O-N 3.14Å; E282-A286 WeakPolarHBondContact O-CB 3.38Å; E282-A286 PolarHBondContact O-N 3.47Å
283	V	91.5	Very high	90.7	Very high	4 Å²	4	64.5 Å²	64.5	2%	0.024	29%	0.292	C	S	.	.	H	α-helix	trans	-58.6	-41.7	173.8	175.9	0	0	0	0	111.3	V121 V122 V275 N279 N287 F464	V121-V283 HydrophobicContact CG1-CG1 4.24Å; V122-V283 HydrophobicContact CG2-CG1 3.84Å; V275-V283 HydrophobicContact CG1-CG2 4.31Å; N279-V283 PolarHBondContact O-N 3.27Å; V283-N287 WeakPolarHBondContact O-CB 3.38Å; V283-N287 VanDerWaalsContact O-CG 3.29Å; V283-N287 PolarHBondContact O-N 3.21Å; V283-N287 PolarHBondContact O-ND2 2.98Å; V283-F464 HydrophobicContact CB-CE2 4.18Å; V283-F464 HydrophobicContact CB-CZ 4Å; V283-F464 HydrophobicContact CG1-CD2 4.17Å; V283-F464 HydrophobicContact CG1-CE1 4.2Å; V283-F464 HydrophobicContact CG1-CE2 3.7Å; V283-F464 HydrophobicContact CG1-CZ 3.71Å
284	K	91.6	Very high	91	Very high	152 Å²	152	64.3 Å²	64.3	66%	0.661	29%	0.292	S	S	*	.	H	α-helix	trans	-67.2	-39.3	176.3	-171.5	176.4	-178.7	177.5	0	112.1	K280 K281 E282 K288 F464	K280-K284 WeakPolarHBondContact O-CB 3.44Å; K280-K284 PolarHBondContact O-N 3.48Å; K280-K284 VanDerWaalsContact O-N 3.12Å; K281-K284 PolarHBondContact O-N 2.81Å; E282-K284 VanDerWaalsContact C-N 3.28Å; E282-K284 PolarHBondContact O-N 2.94Å; K284-K288 PolarHBondContact O-N 3.07Å; K284-F464 HydrophobicContact CB-CE1 4.24Å
285	E	91.4	Very high	91.5	Very high	51 Å²	51	61.5 Å²	61.5	24%	0.238	28%	0.282	C	S	.	.	H	α-helix	trans	-66.7	-46.6	176.9	-175.2	173.7	-154.1	0	0	111.3	K63 K281 E282 N287 K288 Y289	K63-E285 WeakPolarHBondContact CD-OE1 3.13Å; K63-E285 IonicContact NZ-OE1 2.75Å; K63-E285 PolarHBondContact NZ-OE1 3.29Å; K63-E285 IonicContact NZ-OE2 2.87Å; K63-E285 PolarHBondContact NZ-OE2 3.39Å; K281-E285 WeakPolarHBondContact O-CB 3.4Å; K281-E285 PolarHBondContact O-N 3.03Å; E282-E285 PolarHBondContact O-N 3.4Å; E282-E285 VanDerWaalsContact O-N 3.14Å; E285-N287 PolarHBondContact O-N 3.45Å; E285-K288 WeakPolarHBondContact O-CB 3.46Å; E285-K288 PolarHBondContact O-N 3.06Å; E285-K288 VanDerWaalsContact O-N 3.07Å; E285-Y289 HydrophobicContact CG-CD2 3.7Å; E285-Y289 HydrophobicContact CG-CE2 3.38Å; E285-Y289 VanDerWaalsContact O-CD2 3.28Å; E285-Y289 WeakPolarHBondContact O-CD2 3.38Å; E285-Y289 PolarHBondContact O-N 3.16Å; E285-Y289 WeakPolarHBondContact OE1-CE2 3.4Å
286	A	91.9	Very high	92	Very high	1 Å²	1	64 Å²	64	1%	0.008	29%	0.294	C	S	.	.	H	α-helix	trans	-58.1	-48.1	175.7	0	0	0	0	0	111.4	F67 V121 V275 E282 K288 Y289 F290	F67-A286 HydrophobicContact CE1-CB 3.88Å; F67-A286 HydrophobicContact CZ-CB 3.87Å; V121-A286 HydrophobicContact CG1-CB 3.88Å; V275-A286 HydrophobicContact CG1-CB 4.03Å; V275-A286 HydrophobicContact CG2-CB 3.83Å; E282-A286 WeakPolarHBondContact O-CB 3.38Å; E282-A286 PolarHBondContact O-N 3.47Å; A286-K288 PolarHBondContact O-N 2.92Å; A286-Y289 PolarHBondContact O-N 3Å; A286-Y289 VanDerWaalsContact O-N 3.16Å; A286-F290 HydrophobicContact CB-CD2 4.33Å; A286-F290 HydrophobicContact CB-CE2 4.31Å; A286-F290 WeakPolarHBondContact O-CD2 3.33Å; A286-F290 PolarHBondContact O-N 3.46Å
287	N	93	Very high	92.3	Very high	22 Å²	22	60.5 Å²	60.5	12%	0.118	28%	0.275	C	S	.	.	H	α-helix	trans	-58	-33.2	175.3	-79.6	-40.7	0	0	0	113.1	R118 V283 E285 F291	R118-N287 WeakPolarHBondContact CG-OD1 3.37Å; V283-N287 WeakPolarHBondContact O-CB 3.38Å; V283-N287 VanDerWaalsContact O-CG 3.29Å; V283-N287 PolarHBondContact O-N 3.21Å; V283-N287 PolarHBondContact O-ND2 2.98Å; E285-N287 PolarHBondContact O-N 3.45Å; N287-F291 VanDerWaalsContact O-CB 3.3Å; N287-F291 WeakPolarHBondContact O-CB 3.22Å; N287-F291 PolarHBondContact O-N 3.22Å
288	K	93	Very high	92.8	Very high	87 Å²	87	55.3 Å²	55.3	38%	0.378	26%	0.256	S	S	.	.	H	α-helix	trans	-69.9	-48.4	175.1	179.1	-174.3	173.9	-178.1	0	111.2	M58 K284 E285 A286 F291 I292	M58-K288 PolarHBondContact O-NZ 2.75Å; K284-K288 PolarHBondContact O-N 3.07Å; E285-K288 WeakPolarHBondContact O-CB 3.46Å; E285-K288 PolarHBondContact O-N 3.06Å; E285-K288 VanDerWaalsContact O-N 3.07Å; A286-K288 PolarHBondContact O-N 2.92Å; K288-F291 PolarHBondContact O-N 3.41Å; K288-I292 HydrophobicContact CG-CD1 4.03Å; K288-I292 WeakPolarHBondContact O-CG1 3.34Å; K288-I292 PolarHBondContact O-N 3.11Å; K288-I292 VanDerWaalsContact O-N 3.07Å
289	Y	94.3	Very high	93.2	Very high	0 Å²	0	52.2 Å²	52.2	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-67.7	-43.5	-178.5	-75.5	-69.4	0	0	0	112.6	F59 S60 K63 L64 F67 E285 A286 F291 I292 E293	F59-Y289 AromaticContact CD2-CE1 3.91Å; F59-Y289 HydrophobicContact CD2-CE1 3.91Å; F59-Y289 AromaticContact CE2-CE1 3.96Å; F59-Y289 HydrophobicContact CE2-CE1 3.96Å; S60-Y289 PolarHBondContact N-OH 3.48Å; K63-Y289 HydrophobicContact CB-CE1 4.18Å; K63-Y289 HydrophobicContact CB-CE2 4.02Å; K63-Y289 HydrophobicContact CD-CE2 4.06Å; L64-Y289 HydrophobicContact CB-CD1 4.06Å; L64-Y289 HydrophobicContact CB-CE1 4.15Å; L64-Y289 HydrophobicContact CD1-CD1 4Å; F67-Y289 AromaticContact CD2-CD2 3.79Å; F67-Y289 HydrophobicContact CD2-CD2 3.79Å; F67-Y289 AromaticContact CD2-CG 3.76Å; F67-Y289 HydrophobicContact CD2-CG 3.76Å; F67-Y289 AromaticContact CE2-CD2 3.68Å; F67-Y289 HydrophobicContact CE2-CD2 3.68Å; F67-Y289 HydrophobicContact CE2-CE2 4.43Å; F67-Y289 HydrophobicContact CE2-CG 4.13Å; F67-Y289 HydrophobicContact CG-CG 4.4Å; E285-Y289 HydrophobicContact CG-CD2 3.7Å; E285-Y289 HydrophobicContact CG-CE2 3.38Å; E285-Y289 VanDerWaalsContact O-CD2 3.28Å; E285-Y289 WeakPolarHBondContact O-CD2 3.38Å; E285-Y289 PolarHBondContact O-N 3.16Å; E285-Y289 WeakPolarHBondContact OE1-CE2 3.4Å; A286-Y289 PolarHBondContact O-N 3Å; A286-Y289 VanDerWaalsContact O-N 3.16Å; Y289-F291 VanDerWaalsContact C-N 3.27Å; Y289-F291 PolarHBondContact O-N 3.27Å; Y289-I292 PolarHBondContact O-N 3.17Å; Y289-E293 WeakPolarHBondContact O-CB 3.33Å; Y289-E293 PolarHBondContact O-N 3.11Å
290	F	94.6	Very high	93.6	Very high	1 Å²	1	51.7 Å²	51.7	0%	0.004	24%	0.241	C	C	.	.	H	α-helix	trans	-60.9	-36.9	175	-76.9	-56.2	0	0	0	112.4	F67 P70 V121 V270 R273 A286 S294	F67-F290 HydrophobicContact CD1-CD1 4.34Å; F67-F290 HydrophobicContact CD1-CD2 4.25Å; F67-F290 AromaticContact CD1-CE1 3.89Å; F67-F290 HydrophobicContact CD1-CE1 3.89Å; F67-F290 AromaticContact CD1-CE2 3.8Å; F67-F290 HydrophobicContact CD1-CE2 3.8Å; F67-F290 AromaticContact CD1-CZ 3.62Å; F67-F290 HydrophobicContact CD1-CZ 3.62Å; F67-F290 HydrophobicContact CE1-CD2 4.32Å; F67-F290 AromaticContact CE1-CE2 3.76Å; F67-F290 HydrophobicContact CE1-CE2 3.76Å; F67-F290 AromaticContact CE1-CZ 3.95Å; F67-F290 HydrophobicContact CE1-CZ 3.95Å; P70-F290 HydrophobicContact CB-CE1 4.21Å; P70-F290 HydrophobicContact CG-CE1 3.99Å; V121-F290 HydrophobicContact CG2-CD2 3.51Å; V121-F290 HydrophobicContact CG2-CE2 3.52Å; V270-F290 HydrophobicContact CB-CD2 4.45Å; V270-F290 HydrophobicContact CB-CE1 4.13Å; V270-F290 HydrophobicContact CB-CE2 4.03Å; V270-F290 HydrophobicContact CB-CZ 3.83Å; V270-F290 HydrophobicContact CG1-CD1 3.89Å; V270-F290 HydrophobicContact CG1-CD2 4.32Å; V270-F290 HydrophobicContact CG1-CE1 3.89Å; V270-F290 HydrophobicContact CG1-CE2 4.31Å; V270-F290 HydrophobicContact CG1-CG 4.1Å; V270-F290 HydrophobicContact CG1-CZ 4.08Å; R273-F290 HydrophobicContact CB-CZ 3.95Å; R273-F290 HydrophobicContact CG-CE1 4.09Å; R273-F290 HydrophobicContact CG-CZ 3.69Å; A286-F290 HydrophobicContact CB-CD2 4.33Å; A286-F290 HydrophobicContact CB-CE2 4.31Å; A286-F290 WeakPolarHBondContact O-CD2 3.33Å; A286-F290 PolarHBondContact O-N 3.46Å; F290-S294 VanDerWaalsContact O-CB 3.26Å; F290-S294 WeakPolarHBondContact O-CB 3.32Å; F290-S294 PolarHBondContact O-N 2.92Å; F290-S294 PolarHBondContact O-OG 3.49Å
291	F	95.1	Very high	93.9	Very high	66 Å²	66	45.7 Å²	45.7	29%	0.289	22%	0.215	S	C	.	.	H	α-helix	trans	-66.1	-44.8	175	178.7	-110.5	0	0	0	112.3	L110 R114 N287 K288 Y289 S295	L110-F291 HydrophobicContact CD1-CE2 4.28Å; L110-F291 HydrophobicContact CD2-CE2 4.37Å; L110-F291 HydrophobicContact CG-CE2 4.25Å; R114-F291 HydrophobicContact CB-CD2 4.14Å; R114-F291 HydrophobicContact CG-CD2 3.83Å; R114-F291 HydrophobicContact CG-CE2 4.39Å; N287-F291 VanDerWaalsContact O-CB 3.3Å; N287-F291 WeakPolarHBondContact O-CB 3.22Å; N287-F291 PolarHBondContact O-N 3.22Å; K288-F291 PolarHBondContact O-N 3.41Å; Y289-F291 VanDerWaalsContact C-N 3.27Å; Y289-F291 PolarHBondContact O-N 3.27Å; F291-S295 WeakPolarHBondContact O-CB 3.34Å; F291-S295 PolarHBondContact O-N 2.88Å; F291-S295 PolarHBondContact O-OG 3.05Å
292	I	94.9	Very high	94.2	Very high	44 Å²	44	38.3 Å²	38.3	23%	0.226	18%	0.183	C	C	.	.	H	α-helix	trans	-61.5	-48	177.5	-68.5	167.4	0	0	0	110.3	F59 L64 K288 Y289 S295 I296	F59-I292 HydrophobicContact CD2-CD1 4.37Å; F59-I292 HydrophobicContact CE2-CD1 4.01Å; L64-I292 HydrophobicContact CD1-CB 4.46Å; L64-I292 HydrophobicContact CD1-CG2 4.01Å; K288-I292 HydrophobicContact CG-CD1 4.03Å; K288-I292 WeakPolarHBondContact O-CG1 3.34Å; K288-I292 PolarHBondContact O-N 3.11Å; K288-I292 VanDerWaalsContact O-N 3.07Å; Y289-I292 PolarHBondContact O-N 3.17Å; I292-S295 WeakPolarHBondContact O-CB 3.2Å; I292-S295 PolarHBondContact O-N 2.98Å; I292-I296 HydrophobicContact CG2-CD1 3.95Å; I292-I296 WeakPolarHBondContact O-CG1 3.47Å; I292-I296 PolarHBondContact O-N 3.31Å
293	E	94.9	Very high	94.6	Very high	2 Å²	2	38.7 Å²	38.7	1%	0.009	19%	0.187	C	C	.	.	H	α-helix	trans	-59.9	-52.5	178.8	-175.8	-140.5	178.4	0	0	111.7	G69 G71 Y289 S295 I296 A297	G69-E293 PolarHBondContact N-OE1 3.22Å; G71-E293 WeakPolarHBondContact CA-OE1 2.92Å; G71-E293 PolarHBondContact N-OE1 3.11Å; G71-E293 PolarHBondContact N-OE2 2.91Å; Y289-E293 WeakPolarHBondContact O-CB 3.33Å; Y289-E293 PolarHBondContact O-N 3.11Å; E293-S295 PolarHBondContact O-N 2.84Å; E293-I296 PolarHBondContact O-N 3.1Å; E293-I296 VanDerWaalsContact O-N 3.1Å; E293-A297 WeakPolarHBondContact O-CB 3.36Å; E293-A297 PolarHBondContact O-N 3.33Å
294	S	95.3	Very high	94.9	Very high	2 Å²	2	38.6 Å²	38.6	1%	0.014	19%	0.186	C	C	.	.	H	α-helix	trans	-59.6	-35	178.4	-60.1	0	0	0	0	112.2	H266 F290 L298	H266-S294 PolarHBondContact CE1-OG 3.43Å; H266-S294 PolarHBondContact NE2-OG 2.93Å; F290-S294 VanDerWaalsContact O-CB 3.26Å; F290-S294 WeakPolarHBondContact O-CB 3.32Å; F290-S294 PolarHBondContact O-N 2.92Å; F290-S294 PolarHBondContact O-OG 3.49Å; S294-L298 WeakPolarHBondContact O-CB 3.47Å; S294-L298 WeakPolarHBondContact O-CG 3.22Å; S294-L298 PolarHBondContact O-N 3.5Å
295	S	96.6	Very high	95.1	Very high	32 Å²	32	31.5 Å²	31.5	22%	0.224	16%	0.156	C	C	.	.	H	α-helix	trans	-66.3	-42.2	176.1	-57.6	0	0	0	0	111.6	F291 I292 E293 F299	F291-S295 WeakPolarHBondContact O-CB 3.34Å; F291-S295 PolarHBondContact O-N 2.88Å; F291-S295 PolarHBondContact O-OG 3.05Å; I292-S295 WeakPolarHBondContact O-CB 3.2Å; I292-S295 PolarHBondContact O-N 2.98Å; E293-S295 PolarHBondContact O-N 2.84Å; S295-F299 WeakPolarHBondContact O-CB 3.36Å; S295-F299 PolarHBondContact O-N 3.33Å
296	I	96	Very high	95.3	Very high	78 Å²	78	29.4 Å²	29.4	40%	0.4	15%	0.146	S	C	.	.	H	α-helix	trans	-66.1	-47.2	176.6	-66.8	165.9	0	0	0	110	F72 I292 E293 F299 V300	F72-I296 HydrophobicContact CZ-CG2 4.26Å; I292-I296 HydrophobicContact CG2-CD1 3.95Å; I292-I296 WeakPolarHBondContact O-CG1 3.47Å; I292-I296 PolarHBondContact O-N 3.31Å; E293-I296 PolarHBondContact O-N 3.1Å; E293-I296 VanDerWaalsContact O-N 3.1Å; I296-F299 PolarHBondContact O-N 2.95Å; I296-V300 WeakPolarHBondContact O-CG2 3.3Å; I296-V300 PolarHBondContact O-N 3.48Å
297	A	95.3	Very high	95.6	Very high	0 Å²	0	31 Å²	31	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-61.6	-48.6	-178.7	0	0	0	0	0	111.9	G71 F72 E293 F299 V300 S301	G71-A297 WeakPolarHBondContact O-CB 3.46Å; F72-A297 HydrophobicContact CD1-CB 4.03Å; F72-A297 HydrophobicContact CD2-CB 4.26Å; F72-A297 HydrophobicContact CE1-CB 4.25Å; F72-A297 HydrophobicContact CE2-CB 4.46Å; F72-A297 HydrophobicContact CG-CB 4.04Å; F72-A297 HydrophobicContact CZ-CB 4.47Å; E293-A297 WeakPolarHBondContact O-CB 3.36Å; E293-A297 PolarHBondContact O-N 3.33Å; A297-F299 VanDerWaalsContact C-N 3.32Å; A297-F299 PolarHBondContact O-N 3.47Å; A297-V300 PolarHBondContact O-N 3.28Å; A297-S301 PolarHBondContact O-N 3.04Å; A297-S301 PolarHBondContact O-OG 3.36Å
298	L	95.6	Very high	95.7	Very high	3 Å²	3	30.1 Å²	30.1	2%	0.016	15%	0.148	C	C	.	.	H	α-helix	trans	-69.1	-27.4	177	-71.5	179.6	0	0	0	113.5	M74 Y78 L110 Q113 S294 S301 F302	M74-L298 HydrophobicContact CE-CD1 3.95Å; M74-L298 HydrophobicContact CE-CD2 4.17Å; M74-L298 HydrophobicContact CE-CG 3.9Å; M74-L298 HydrophobicContact SD-CD1 4.35Å; M74-L298 HydrophobicContact SD-CD2 3.89Å; M74-L298 HydrophobicContact SD-CG 4.27Å; Y78-L298 HydrophobicContact CD1-CD2 3.83Å; Y78-L298 HydrophobicContact CD2-CD2 3.41Å; Y78-L298 VanDerWaalsContact CD2-CD2 3.41Å; Y78-L298 HydrophobicContact CE1-CD2 3.87Å; Y78-L298 HydrophobicContact CE2-CD2 3.46Å; Y78-L298 VanDerWaalsContact CE2-CD2 3.46Å; Y78-L298 HydrophobicContact CG-CD2 3.62Å; L110-L298 HydrophobicContact CB-CD1 3.71Å; L110-L298 HydrophobicContact CD1-CD1 3.87Å; L110-L298 HydrophobicContact CG-CD1 4.39Å; Q113-L298 HydrophobicContact CG-CD1 4.44Å; S294-L298 WeakPolarHBondContact O-CB 3.47Å; S294-L298 WeakPolarHBondContact O-CG 3.22Å; S294-L298 PolarHBondContact O-N 3.5Å; L298-S301 PolarHBondContact O-N 3.04Å; L298-F302 WeakPolarHBondContact O-CB 3.48Å; L298-F302 PolarHBondContact O-N 2.85Å
299	F	96.7	Very high	95.8	Very high	131 Å²	131	26 Å²	26	58%	0.575	13%	0.131	S	C	*	.	H	α-helix	trans	-67.1	-40.5	171.9	178.2	-103.5	0	0	0	111.7	S295 I296 A297 F302 L303	S295-F299 WeakPolarHBondContact O-CB 3.36Å; S295-F299 PolarHBondContact O-N 3.33Å; I296-F299 PolarHBondContact O-N 2.95Å; A297-F299 VanDerWaalsContact C-N 3.32Å; A297-F299 PolarHBondContact O-N 3.47Å; F299-F302 PolarHBondContact O-N 3.25Å; F299-L303 PolarHBondContact O-N 2.76Å
300	V	96.3	Very high	95.9	Very high	45 Å²	45	26 Å²	26	27%	0.273	13%	0.131	S	C	.	.	H	α-helix	trans	-63.7	-45.8	173.3	173.7	0	0	0	0	110.4	I209 I296 A297 L303 I304	I209-V300 HydrophobicContact CG2-CG1 4.06Å; I296-V300 WeakPolarHBondContact O-CG2 3.3Å; I296-V300 PolarHBondContact O-N 3.48Å; A297-V300 PolarHBondContact O-N 3.28Å; V300-L303 PolarHBondContact O-N 2.65Å; V300-I304 HydrophobicContact CG1-CD1 4.32Å; V300-I304 WeakPolarHBondContact O-CG1 3.4Å; V300-I304 PolarHBondContact O-N 3.07Å
301	S	95.9	Very high	95.9	Very high	1 Å²	1	26 Å²	26	1%	0.007	13%	0.131	C	C	.	.	H	α-helix	trans	-58.6	-52.9	175.5	-61.9	0	0	0	0	110.7	S75 L79 A297 L298 L303 I304 N305	S75-S301 VanDerWaalsContact CB-OG 3.3Å; S75-S301 WeakPolarHBondContact CB-OG 3.38Å; S75-S301 PolarHBondContact O-OG 3.49Å; S75-S301 PolarHBondContact OG-OG 3.33Å; L79-S301 WeakPolarHBondContact CD1-OG 3.29Å; A297-S301 PolarHBondContact O-N 3.04Å; A297-S301 PolarHBondContact O-OG 3.36Å; L298-S301 PolarHBondContact O-N 3.04Å; S301-L303 PolarHBondContact O-N 3.38Å; S301-L303 VanDerWaalsContact O-N 3.11Å; S301-I304 WeakPolarHBondContact O-CA 3.39Å; S301-I304 VanDerWaalsContact O-CB 3.3Å; S301-I304 WeakPolarHBondContact O-CB 3.35Å; S301-I304 PolarHBondContact O-N 3.48Å; S301-N305 PolarHBondContact O-N 3.38Å; S301-N305 PolarHBondContact O-OD1 3.01Å
302	F	96.6	Very high	95.8	Very high	16 Å²	16	22.9 Å²	22.9	7%	0.07	12%	0.117	C	C	.	.	H	α-helix	trans	-50.4	-41.8	177	174.1	-109.8	0	0	0	113.5	L102 L103 T106 M234 L298 F299 I304 N305 V306	L102-F302 HydrophobicContact CD2-CE2 4.27Å; L102-F302 HydrophobicContact CG-CD2 4.23Å; L102-F302 HydrophobicContact CG-CE2 4.03Å; L103-F302 HydrophobicContact CB-CE2 3.89Å; L103-F302 HydrophobicContact CB-CZ 3.9Å; L103-F302 HydrophobicContact CD1-CE1 3.91Å; L103-F302 HydrophobicContact CD1-CE2 3.95Å; L103-F302 HydrophobicContact CD1-CZ 3.51Å; L103-F302 HydrophobicContact CG-CZ 4.25Å; T106-F302 HydrophobicContact CG2-CB 3.87Å; T106-F302 HydrophobicContact CG2-CD2 4.25Å; T106-F302 HydrophobicContact CG2-CG 4.35Å; M234-F302 HydrophobicContact CE-CE1 3.68Å; M234-F302 HydrophobicContact CE-CZ 3.64Å; L298-F302 WeakPolarHBondContact O-CB 3.48Å; L298-F302 PolarHBondContact O-N 2.85Å; F299-F302 PolarHBondContact O-N 3.25Å; F302-I304 VanDerWaalsContact C-N 3.32Å; F302-I304 PolarHBondContact O-N 3Å; F302-N305 PolarHBondContact O-N 3.04Å; F302-V306 HydrophobicContact CD1-CG2 4.35Å; F302-V306 HydrophobicContact CD2-CG2 4.15Å; F302-V306 HydrophobicContact CE1-CG2 3.88Å; F302-V306 HydrophobicContact CE2-CG2 3.63Å; F302-V306 HydrophobicContact CG-CG2 4.49Å; F302-V306 HydrophobicContact CZ-CG2 3.49Å; F302-V306 VanDerWaalsContact CZ-CG2 3.49Å; F302-V306 VanDerWaalsContact O-CG2 3.3Å; F302-V306 WeakPolarHBondContact O-CG2 3.3Å; F302-V306 PolarHBondContact O-N 3.19Å
303	L	96.4	Very high	95.7	Very high	74 Å²	74	21 Å²	21	39%	0.387	11%	0.108	S	C	.	.	H	α-helix	trans	-62.3	-40.6	177.1	-175.6	65.3	0	0	0	111.9	F299 V300 S301 V306 F307	F299-L303 PolarHBondContact O-N 2.76Å; V300-L303 PolarHBondContact O-N 2.65Å; S301-L303 PolarHBondContact O-N 3.38Å; S301-L303 VanDerWaalsContact O-N 3.11Å; L303-V306 PolarHBondContact O-N 3.43Å; L303-F307 HydrophobicContact CD1-CD1 4.45Å; L303-F307 HydrophobicContact CD1-CE1 3.67Å; L303-F307 HydrophobicContact CD1-CZ 3.72Å; L303-F307 HydrophobicContact CD2-CE2 4.19Å; L303-F307 HydrophobicContact CD2-CZ 3.81Å; L303-F307 HydrophobicContact CG-CE1 3.91Å; L303-F307 HydrophobicContact CG-CE2 3.85Å; L303-F307 HydrophobicContact CG-CZ 3.49Å; L303-F307 VanDerWaalsContact CG-CZ 3.49Å; L303-F307 WeakPolarHBondContact O-CD1 3.39Å; L303-F307 VanDerWaalsContact O-CG 3.22Å; L303-F307 WeakPolarHBondContact O-CG 3.48Å; L303-F307 PolarHBondContact O-N 3.25Å
304	I	96.8	Very high	95.6	Very high	2 Å²	2	24.9 Å²	24.9	1%	0.01	13%	0.126	C	C	.	.	H	α-helix	trans	-64.6	-47.5	175.2	-64	166.5	0	0	0	110.7	L79 I209 M212 A213 F216 V300 S301 F302 V306 F307 V308	L79-I304 HydrophobicContact CD1-CD1 3.66Å; L79-I304 HydrophobicContact CD2-CB 3.69Å; L79-I304 HydrophobicContact CD2-CD1 3.98Å; L79-I304 HydrophobicContact CD2-CG1 4.44Å; L79-I304 HydrophobicContact CD2-CG2 3.66Å; L79-I304 HydrophobicContact CG-CD1 4.49Å; I209-I304 HydrophobicContact CG2-CD1 4.39Å; M212-I304 HydrophobicContact CB-CD1 4.37Å; A213-I304 HydrophobicContact CB-CD1 4.01Å; A213-I304 HydrophobicContact CB-CG1 4.16Å; F216-I304 HydrophobicContact CB-CG2 4.36Å; F216-I304 HydrophobicContact CD2-CG2 3.45Å; F216-I304 VanDerWaalsContact CD2-CG2 3.45Å; F216-I304 HydrophobicContact CE2-CG2 4.16Å; F216-I304 HydrophobicContact CG-CG2 4.31Å; V300-I304 HydrophobicContact CG1-CD1 4.32Å; V300-I304 WeakPolarHBondContact O-CG1 3.4Å; V300-I304 PolarHBondContact O-N 3.07Å; S301-I304 WeakPolarHBondContact O-CA 3.39Å; S301-I304 VanDerWaalsContact O-CB 3.3Å; S301-I304 WeakPolarHBondContact O-CB 3.35Å; S301-I304 PolarHBondContact O-N 3.48Å; F302-I304 VanDerWaalsContact C-N 3.32Å; F302-I304 PolarHBondContact O-N 3Å; I304-V306 VanDerWaalsContact C-N 3.3Å; I304-V306 PolarHBondContact O-N 2.94Å; I304-F307 WeakPolarHBondContact O-CB 3.33Å; I304-F307 PolarHBondContact O-N 3.34Å; I304-V308 PolarHBondContact O-N 3.06Å
305	N	96.5	Very high	95.2	Very high	4 Å²	4	25.1 Å²	25.1	2%	0.021	13%	0.128	C	C	.	.	H	α-helix	trans	-55.9	-45.3	175.5	-66.4	76	0	0	0	110.9	Y78 L79 N83 D87 L102 S301 F302 F307 V308 V309	Y78-N305 PolarHBondContact O-ND2 3.46Å; Y78-N305 VanDerWaalsContact O-ND2 3.14Å; Y78-N305 PolarHBondContact O-OD1 2.68Å; L79-N305 WeakPolarHBondContact CD2-OD1 3.28Å; N83-N305 PolarHBondContact OD1-ND2 2.98Å; D87-N305 WeakPolarHBondContact OD2-CA 3.27Å; D87-N305 WeakPolarHBondContact OD2-CB 3.37Å; D87-N305 VanDerWaalsContact OD2-CG 3.23Å; D87-N305 PolarHBondContact OD2-ND2 3.42Å; L102-N305 HydrophobicContact CD1-CB 4.04Å; L102-N305 HydrophobicContact CD2-CB 3.77Å; L102-N305 HydrophobicContact CG-CB 4.41Å; S301-N305 PolarHBondContact O-N 3.38Å; S301-N305 PolarHBondContact O-OD1 3.01Å; F302-N305 PolarHBondContact O-N 3.04Å; N305-F307 VanDerWaalsContact C-N 3.33Å; N305-F307 PolarHBondContact O-N 2.89Å; N305-V308 PolarHBondContact O-N 2.86Å; N305-V309 WeakPolarHBondContact O-CG2 3.43Å; N305-V309 PolarHBondContact O-N 2.86Å
306	V	96.6	Very high	94.7	Very high	7 Å²	7	23.9 Å²	23.9	4%	0.042	12%	0.118	C	C	.	.	H	α-helix	trans	-60.5	-40.6	175	169.8	0	0	0	0	111.9	L99 L102 V230 M234 F302 L303 I304 V308 A310	L99-V306 HydrophobicContact CD2-CG2 4.34Å; L102-V306 HydrophobicContact CD2-CG2 4.11Å; V230-V306 HydrophobicContact CG1-CG1 4.17Å; M234-V306 HydrophobicContact CE-CG2 4.37Å; M234-V306 HydrophobicContact SD-CG1 4.33Å; F302-V306 HydrophobicContact CD1-CG2 4.35Å; F302-V306 HydrophobicContact CD2-CG2 4.15Å; F302-V306 HydrophobicContact CE1-CG2 3.88Å; F302-V306 HydrophobicContact CE2-CG2 3.63Å; F302-V306 HydrophobicContact CG-CG2 4.49Å; F302-V306 HydrophobicContact CZ-CG2 3.49Å; F302-V306 VanDerWaalsContact CZ-CG2 3.49Å; F302-V306 VanDerWaalsContact O-CG2 3.3Å; F302-V306 WeakPolarHBondContact O-CG2 3.3Å; F302-V306 PolarHBondContact O-N 3.19Å; L303-V306 PolarHBondContact O-N 3.43Å; I304-V306 VanDerWaalsContact C-N 3.3Å; I304-V306 PolarHBondContact O-N 2.94Å; V306-V308 VanDerWaalsContact C-N 3.35Å; V306-V308 PolarHBondContact O-N 3.31Å; V306-A310 WeakPolarHBondContact O-CB 3.04Å; V306-A310 PolarHBondContact O-N 3.11Å
307	F	96.3	Very high	94.2	Very high	34 Å²	34	23.7 Å²	23.7	15%	0.149	11%	0.113	C	C	.	.	H	α-helix	trans	-59.2	-46.7	175.7	-65.7	-23	0	0	0	111.6	F216 Y220 L303 I304 N305 V311	F216-F307 HydrophobicContact CB-CB 4.35Å; Y220-F307 AromaticContact CD1-CD1 3.95Å; Y220-F307 HydrophobicContact CD1-CD1 3.95Å; Y220-F307 HydrophobicContact CD1-CE1 4.01Å; Y220-F307 HydrophobicContact CD2-CB 4.2Å; Y220-F307 AromaticContact CD2-CD1 3.64Å; Y220-F307 HydrophobicContact CD2-CD1 3.64Å; Y220-F307 HydrophobicContact CD2-CE1 4.46Å; Y220-F307 HydrophobicContact CD2-CG 4.28Å; Y220-F307 HydrophobicContact CE1-CD1 4.36Å; Y220-F307 HydrophobicContact CE1-CE1 4.28Å; Y220-F307 HydrophobicContact CE2-CD1 4.05Å; Y220-F307 HydrophobicContact CG-CB 4.36Å; Y220-F307 AromaticContact CG-CD1 3.55Å; Y220-F307 HydrophobicContact CG-CD1 3.55Å; Y220-F307 HydrophobicContact CG-CE1 4.1Å; Y220-F307 HydrophobicContact CG-CG 4.15Å; L303-F307 HydrophobicContact CD1-CD1 4.45Å; L303-F307 HydrophobicContact CD1-CE1 3.67Å; L303-F307 HydrophobicContact CD1-CZ 3.72Å; L303-F307 HydrophobicContact CD2-CE2 4.19Å; L303-F307 HydrophobicContact CD2-CZ 3.81Å; L303-F307 HydrophobicContact CG-CE1 3.91Å; L303-F307 HydrophobicContact CG-CE2 3.85Å; L303-F307 HydrophobicContact CG-CZ 3.49Å; L303-F307 VanDerWaalsContact CG-CZ 3.49Å; L303-F307 WeakPolarHBondContact O-CD1 3.39Å; L303-F307 VanDerWaalsContact O-CG 3.22Å; L303-F307 WeakPolarHBondContact O-CG 3.48Å; L303-F307 PolarHBondContact O-N 3.25Å; I304-F307 WeakPolarHBondContact O-CB 3.33Å; I304-F307 PolarHBondContact O-N 3.34Å; N305-F307 VanDerWaalsContact C-N 3.33Å; N305-F307 PolarHBondContact O-N 2.89Å; F307-V311 WeakPolarHBondContact O-CB 3.26Å; F307-V311 VanDerWaalsContact O-CG2 3.23Å; F307-V311 WeakPolarHBondContact O-CG2 3.33Å; F307-V311 PolarHBondContact O-N 2.75Å
308	V	95.8	Very high	93.7	Very high	3 Å²	3	29.8 Å²	29.8	2%	0.018	15%	0.146	C	C	.	.	H	α-helix	trans	-61.3	-57.7	177.5	176.6	0	0	0	0	110.2	I84 D87 L88 F216 I304 N305 V306 A310 V311 F312 W369	I84-V308 HydrophobicContact CG2-CG1 4.15Å; I84-V308 HydrophobicContact CG2-CG2 4.44Å; D87-V308 HydrophobicContact CB-CB 4.4Å; D87-V308 HydrophobicContact CB-CG1 4.01Å; L88-V308 HydrophobicContact CB-CG1 3.92Å; F216-V308 HydrophobicContact CB-CG2 4.32Å; F216-V308 HydrophobicContact CD1-CG2 4.2Å; F216-V308 HydrophobicContact CD2-CG2 4.3Å; F216-V308 HydrophobicContact CG-CG2 4.02Å; I304-V308 PolarHBondContact O-N 3.06Å; N305-V308 PolarHBondContact O-N 2.86Å; V306-V308 VanDerWaalsContact C-N 3.35Å; V306-V308 PolarHBondContact O-N 3.31Å; V308-A310 VanDerWaalsContact C-N 3.26Å; V308-A310 PolarHBondContact O-N 3.19Å; V308-V311 PolarHBondContact O-N 3.27Å; V308-F312 HydrophobicContact CG1-CD2 4.02Å; V308-F312 HydrophobicContact CG1-CE2 4.26Å; V308-F312 VanDerWaalsContact O-CD2 3.3Å; V308-F312 WeakPolarHBondContact O-CD2 3.17Å; V308-F312 PolarHBondContact O-N 3.46Å; V308-F312 VanDerWaalsContact O-N 3.1Å; V308-W369 HydrophobicContact CG1-CH2 4.32Å
309	V	95.6	Very high	93.2	Very high	1 Å²	1	33.3 Å²	33.3	1%	0.006	16%	0.161	C	C	.	.	H	α-helix	trans	-54	-44.8	-178.4	177.7	0	0	0	0	111.3	D87 L99 L102 N305 F312 A313	D87-V309 HydrophobicContact CB-CG2 3.6Å; L99-V309 HydrophobicContact CD2-CB 3.83Å; L99-V309 HydrophobicContact CD2-CG1 3.58Å; L99-V309 HydrophobicContact CD2-CG2 4.42Å; L99-V309 HydrophobicContact CG-CG1 4.02Å; L102-V309 HydrophobicContact CD2-CG2 3.94Å; N305-V309 WeakPolarHBondContact O-CG2 3.43Å; N305-V309 PolarHBondContact O-N 2.86Å; V309-F312 PolarHBondContact O-N 2.85Å; V309-A313 WeakPolarHBondContact O-CB 3.08Å; V309-A313 PolarHBondContact O-N 3.4Å
310	A	95.6	Very high	92.8	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-70.5	-38.8	-176.4	0	0	0	0	0	113.6	F96 Y220 P225 V230 V306 V308 Q314	F96-A310 HydrophobicContact CE1-CB 4.09Å; Y220-A310 HydrophobicContact CD2-CB 3.99Å; Y220-A310 HydrophobicContact CE2-CB 3.56Å; P225-A310 HydrophobicContact CB-CB 4.18Å; P225-A310 HydrophobicContact CG-CB 4.07Å; V230-A310 HydrophobicContact CG2-CB 3.93Å; V306-A310 WeakPolarHBondContact O-CB 3.04Å; V306-A310 PolarHBondContact O-N 3.11Å; V308-A310 VanDerWaalsContact C-N 3.26Å; V308-A310 PolarHBondContact O-N 3.19Å; A310-Q314 WeakPolarHBondContact O-CB 2.89Å; A310-Q314 PolarHBondContact O-N 3.39Å
311	V	95.3	Very high	92.3	Very high	2 Å²	2	26.5 Å²	26.5	1%	0.012	13%	0.13	C	C	.	.	H	α-helix	trans	-59.8	-48.8	174.7	160.2	0	0	0	0	110.2	E219 Y220 V223 F307 V308 Q314 A315 L357	E219-V311 HydrophobicContact CB-CG1 4.47Å; E219-V311 HydrophobicContact CB-CG2 4.01Å; Y220-V311 VanDerWaalsContact CA-CG2 3.46Å; Y220-V311 HydrophobicContact CD2-CG2 4.41Å; V223-V311 HydrophobicContact CB-CG2 4.33Å; V223-V311 HydrophobicContact CG2-CG1 3.98Å; V223-V311 HydrophobicContact CG2-CG2 4.21Å; F307-V311 WeakPolarHBondContact O-CB 3.26Å; F307-V311 VanDerWaalsContact O-CG2 3.23Å; F307-V311 WeakPolarHBondContact O-CG2 3.33Å; F307-V311 PolarHBondContact O-N 2.75Å; V308-V311 PolarHBondContact O-N 3.27Å; V311-Q314 PolarHBondContact O-N 2.95Å; V311-A315 VanDerWaalsContact O-CB 3.31Å; V311-A315 WeakPolarHBondContact O-CB 3.36Å; V311-A315 PolarHBondContact O-N 3.45Å; V311-L357 HydrophobicContact CG1-CD2 3.77Å
312	F	93.6	Very high	91.7	Very high	0 Å²	0	30 Å²	30	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-74.8	-32.6	-177.3	-76.3	-89.5	0	0	0	112.7	L88 V308 V309 Q314 F316 V348 L357 W369	L88-F312 HydrophobicContact CB-CB 4.31Å; L88-F312 HydrophobicContact CB-CD1 4.03Å; L88-F312 HydrophobicContact CB-CD2 3.7Å; L88-F312 HydrophobicContact CB-CE1 4.31Å; L88-F312 HydrophobicContact CB-CE2 4.02Å; L88-F312 HydrophobicContact CB-CG 3.73Å; L88-F312 HydrophobicContact CB-CZ 4.32Å; V308-F312 HydrophobicContact CG1-CD2 4.02Å; V308-F312 HydrophobicContact CG1-CE2 4.26Å; V308-F312 VanDerWaalsContact O-CD2 3.3Å; V308-F312 WeakPolarHBondContact O-CD2 3.17Å; V308-F312 PolarHBondContact O-N 3.46Å; V308-F312 VanDerWaalsContact O-N 3.1Å; V309-F312 PolarHBondContact O-N 2.85Å; F312-Q314 PolarHBondContact O-N 2.96Å; F312-F316 HydrophobicContact CB-CD2 4.26Å; F312-F316 AromaticContact CD1-CD2 3.43Å; F312-F316 HydrophobicContact CD1-CD2 3.43Å; F312-F316 VanDerWaalsContact CD1-CD2 3.43Å; F312-F316 HydrophobicContact CD1-CE1 4.45Å; F312-F316 AromaticContact CD1-CE2 3.16Å; F312-F316 HydrophobicContact CD1-CE2 3.16Å; F312-F316 HydrophobicContact CD1-CG 4.21Å; F312-F316 AromaticContact CD1-CZ 3.69Å; F312-F316 HydrophobicContact CD1-CZ 3.69Å; F312-F316 HydrophobicContact CE1-CD2 4.11Å; F312-F316 HydrophobicContact CE1-CE1 4.49Å; F312-F316 AromaticContact CE1-CE2 3.35Å; F312-F316 HydrophobicContact CE1-CE2 3.35Å; F312-F316 AromaticContact CE1-CZ 3.53Å; F312-F316 HydrophobicContact CE1-CZ 3.53Å; F312-F316 HydrophobicContact CG-CD2 4.2Å; F312-F316 HydrophobicContact CG-CE2 4.16Å; F312-F316 HydrophobicContact CZ-CE2 4.45Å; F312-F316 VanDerWaalsContact O-CB 3.31Å; F312-F316 WeakPolarHBondContact O-CB 3.04Å; F312-F316 PolarHBondContact O-N 3.27Å; F312-V348 HydrophobicContact CD1-CG1 3.99Å; F312-V348 HydrophobicContact CE1-CG1 4.13Å; F312-L357 HydrophobicContact CE2-CD1 4.35Å; F312-L357 HydrophobicContact CZ-CD1 3.9Å; F312-L357 HydrophobicContact CZ-CG 4.44Å; F312-W369 HydrophobicContact CD2-CH2 4.49Å; F312-W369 HydrophobicContact CE2-CE3 4.18Å; F312-W369 AromaticContact CE2-CH2 3.37Å; F312-W369 HydrophobicContact CE2-CH2 3.37Å; F312-W369 HydrophobicContact CE2-CZ2 4.05Å; F312-W369 AromaticContact CE2-CZ3 3.45Å; F312-W369 HydrophobicContact CE2-CZ3 3.45Å; F312-W369 VanDerWaalsContact CE2-CZ3 3.45Å; F312-W369 HydrophobicContact CZ-CE3 4.31Å; F312-W369 AromaticContact CZ-CH2 3.59Å; F312-W369 HydrophobicContact CZ-CH2 3.59Å; F312-W369 AromaticContact CZ-CZ2 3.77Å; F312-W369 HydrophobicContact CZ-CZ2 3.77Å; F312-W369 AromaticContact CZ-CZ3 3.88Å; F312-W369 HydrophobicContact CZ-CZ3 3.88Å
313	A	92.9	Very high	91.2	Very high	3 Å²	3	32.7 Å²	32.7	3%	0.025	16%	0.162	C	C	.	.	H	α-helix	trans	-58.8	-46	169.1	0	0	0	0	0	111.7	G91 F96 V309 Y317	G91-A313 VanDerWaalsContact O-CA 3.29Å; G91-A313 WeakPolarHBondContact O-CA 3.44Å; F96-A313 HydrophobicContact CD1-CB 3.9Å; F96-A313 HydrophobicContact CE1-CB 3.68Å; F96-A313 HydrophobicContact CE2-CB 4.35Å; F96-A313 HydrophobicContact CG-CB 4.34Å; F96-A313 HydrophobicContact CZ-CB 3.92Å; V309-A313 WeakPolarHBondContact O-CB 3.08Å; V309-A313 PolarHBondContact O-N 3.4Å; A313-Y317 WeakPolarHBondContact O-CB 3.37Å; A313-Y317 PolarHBondContact O-N 2.92Å
314	Q	91.5	Very high	90.6	Very high	85 Å²	85	29.2 Å²	29.2	40%	0.397	14%	0.144	S	C	.	.	H	α-helix	trans	-71.6	-40.7	-179.6	-173.1	63.3	40.5	0	0	112.7	F96 V223 P225 A310 V311 F312	F96-Q314 HydrophobicContact CZ-CB 4.44Å; V223-Q314 HydrophobicContact CG1-CB 3.77Å; V223-Q314 HydrophobicContact CG1-CG 3.78Å; P225-Q314 HydrophobicContact CB-CB 4.32Å; P225-Q314 HydrophobicContact CG-CB 4.37Å; A310-Q314 WeakPolarHBondContact O-CB 2.89Å; A310-Q314 PolarHBondContact O-N 3.39Å; V311-Q314 PolarHBondContact O-N 2.95Å; F312-Q314 PolarHBondContact O-N 2.96Å
315	A	87	Confident	90.1	Very high	6 Å²	6	30 Å²	30	5%	0.05	15%	0.148	C	C	.	.	H	α-helix	trans	-83.4	-29.4	-172.7	0	0	0	0	0	113.8	V311 K319 F361	V311-A315 VanDerWaalsContact O-CB 3.31Å; V311-A315 WeakPolarHBondContact O-CB 3.36Å; V311-A315 PolarHBondContact O-N 3.45Å; A315-K319 WeakPolarHBondContact O-CG 3.42Å; A315-F361 HydrophobicContact CB-CE2 4.18Å
316	F	86.7	Confident	89.6	Confident	6 Å²	6	36 Å²	36	3%	0.026	18%	0.176	C	C	.	.	H	α-helix	trans	-118.1	-21.2	-169.8	-65.8	-108.7	0	0	0	114.8	A92 F312 N318 K319 L346 V348 V356	A92-F316 HydrophobicContact CB-CB 3.9Å; F312-F316 HydrophobicContact CB-CD2 4.26Å; F312-F316 AromaticContact CD1-CD2 3.43Å; F312-F316 HydrophobicContact CD1-CD2 3.43Å; F312-F316 VanDerWaalsContact CD1-CD2 3.43Å; F312-F316 HydrophobicContact CD1-CE1 4.45Å; F312-F316 AromaticContact CD1-CE2 3.16Å; F312-F316 HydrophobicContact CD1-CE2 3.16Å; F312-F316 HydrophobicContact CD1-CG 4.21Å; F312-F316 AromaticContact CD1-CZ 3.69Å; F312-F316 HydrophobicContact CD1-CZ 3.69Å; F312-F316 HydrophobicContact CE1-CD2 4.11Å; F312-F316 HydrophobicContact CE1-CE1 4.49Å; F312-F316 AromaticContact CE1-CE2 3.35Å; F312-F316 HydrophobicContact CE1-CE2 3.35Å; F312-F316 AromaticContact CE1-CZ 3.53Å; F312-F316 HydrophobicContact CE1-CZ 3.53Å; F312-F316 HydrophobicContact CG-CD2 4.2Å; F312-F316 HydrophobicContact CG-CE2 4.16Å; F312-F316 HydrophobicContact CZ-CE2 4.45Å; F312-F316 VanDerWaalsContact O-CB 3.31Å; F312-F316 WeakPolarHBondContact O-CB 3.04Å; F312-F316 PolarHBondContact O-N 3.27Å; F316-N318 PolarHBondContact O-N 3.37Å; F316-K319 WeakPolarHBondContact O-CB 2.88Å; F316-K319 PolarHBondContact O-N 3.46Å; F316-L346 HydrophobicContact CD1-CD2 3.48Å; F316-L346 VanDerWaalsContact CD1-CD2 3.48Å; F316-L346 HydrophobicContact CD1-CG 4.31Å; F316-L346 HydrophobicContact CE1-CD2 3.84Å; F316-V348 HydrophobicContact CB-CG2 4.16Å; F316-V348 HydrophobicContact CD1-CB 4.28Å; F316-V348 HydrophobicContact CD1-CG1 3.89Å; F316-V348 HydrophobicContact CD1-CG2 3.28Å; F316-V348 HydrophobicContact CE1-CB 4.43Å; F316-V348 HydrophobicContact CE1-CG1 3.67Å; F316-V348 HydrophobicContact CE1-CG2 3.84Å; F316-V348 HydrophobicContact CG-CG1 4.49Å; F316-V348 HydrophobicContact CG-CG2 3.96Å; F316-V348 HydrophobicContact CZ-CG1 4.14Å; F316-V356 HydrophobicContact CD1-CG1 4.29Å; F316-V356 HydrophobicContact CE1-CB 3.59Å; F316-V356 HydrophobicContact CE1-CG1 3.56Å; F316-V356 HydrophobicContact CE1-CG2 3.61Å; F316-V356 HydrophobicContact CE2-CB 4.24Å; F316-V356 HydrophobicContact CE2-CG1 3.77Å; F316-V356 HydrophobicContact CZ-CB 3.32Å; F316-V356 HydrophobicContact CZ-CG1 3.27Å; F316-V356 HydrophobicContact CZ-CG2 3.91Å
317	Y	84.4	Confident	89	Confident	74 Å²	74	39.5 Å²	39.5	29%	0.29	19%	0.192	S	C	.	.	T	Hydrogen-bonded Turn	trans	-61.3	127.6	-175	-171.5	-112.9	0	0	0	111.3	G95 A313 K319	G95-Y317 VanDerWaalsContact N-CD2 3.29Å; A313-Y317 WeakPolarHBondContact O-CB 3.37Å; A313-Y317 PolarHBondContact O-N 2.92Å; Y317-K319 VanDerWaalsContact C-N 3.25Å; Y317-K319 PolarHBondContact O-N 3.25Å
318	N	85.1	Confident	88.5	Confident	128 Å²	128	38 Å²	38	68%	0.684	19%	0.185	S	C	*	.	T	Hydrogen-bonded Turn	trans	57.9	26.4	-174.9	-68.7	-25.1	0	0	0	115.5	F316	F316-N318 PolarHBondContact O-N 3.37Å
319	K	85.9	Confident	87.9	Confident	77 Å²	77	42.4 Å²	42.4	34%	0.335	21%	0.209	S	C	.	.			trans	-94	143.9	172.2	-60.6	-63.1	-175.1	174.6	0	112.1	A315 F316 Y317 L346	A315-K319 WeakPolarHBondContact O-CG 3.42Å; F316-K319 WeakPolarHBondContact O-CB 2.88Å; F316-K319 PolarHBondContact O-N 3.46Å; Y317-K319 VanDerWaalsContact C-N 3.25Å; Y317-K319 PolarHBondContact O-N 3.25Å; K319-L346 PolarHBondContact O-N 2.97Å
320	T	87.3	Confident	87.3	Confident	22 Å²	22	46.1 Å²	46.1	14%	0.135	24%	0.24	C	C	.	.	B	Isolated β-bridge	trans	-101.7	162.3	174.7	69	0	0	0	0	111.4	M322 D323 V324	T320-M322 PolarHBondContact O-N 2.88Å; T320-D323 WeakPolarHBondContact CB-OD2 3.2Å; T320-D323 PolarHBondContact N-OD2 3.3Å; T320-D323 PolarHBondContact O-N 2.96Å; T320-D323 PolarHBondContact OG1-N 3.35Å; T320-D323 PolarHBondContact OG1-OD2 3.14Å; T320-V324 PolarHBondContact O-N 2.89Å
321	N	85.6	Confident	86.4	Confident	11 Å²	11	49.6 Å²	49.6	6%	0.059	26%	0.261	C	S	.	.	H	α-helix	trans	-60.5	-32.8	176.4	-68.9	-38.2	0	0	0	112.4	N325 P340 N342 S344 L346	N321-N325 VanDerWaalsContact O-CB 3.28Å; N321-N325 WeakPolarHBondContact O-CB 3.44Å; N321-N325 PolarHBondContact O-N 2.77Å; N321-P340 WeakPolarHBondContact CB-O 3.35Å; N321-N342 WeakPolarHBondContact CB-OD1 3.49Å; N321-N342 PolarHBondContact ND2-OD1 3.48Å; N321-S344 PolarHBondContact N-O 3.35Å; N321-S344 PolarHBondContact ND2-OG 3.3Å; N321-L346 WeakPolarHBondContact OD1-CD1 3.38Å
322	M	84.2	Confident	85.3	Confident	74 Å²	74	52.4 Å²	52.4	37%	0.365	29%	0.29	S	S	.	.	H	α-helix	trans	-64.1	-43	175.2	-73.6	-175.4	-52.6	0	0	112.4	T320 V324 N325 H326 N342 N343	T320-M322 PolarHBondContact O-N 2.88Å; M322-V324 VanDerWaalsContact C-N 3.34Å; M322-V324 PolarHBondContact O-N 2.7Å; M322-N325 PolarHBondContact O-N 3.47Å; M322-H326 PolarHBondContact O-N 3.2Å; M322-N342 WeakPolarHBondContact CG-O 3.31Å; M322-N343 HydrophobicContact CE-CB 3.68Å; M322-N343 WeakPolarHBondContact CE-OD1 3.4Å
323	D	85.1	Confident	84.3	Confident	73 Å²	73	54.5 Å²	54.5	39%	0.39	30%	0.301	S	S	.	.	H	α-helix	trans	-61.5	-46.3	-180	-57.9	-43.7	0	0	0	110.6	T320 H326 E327	T320-D323 WeakPolarHBondContact CB-OD2 3.2Å; T320-D323 PolarHBondContact N-OD2 3.3Å; T320-D323 PolarHBondContact O-N 2.96Å; T320-D323 PolarHBondContact OG1-N 3.35Å; T320-D323 PolarHBondContact OG1-OD2 3.14Å; D323-H326 PolarHBondContact O-N 3Å; D323-E327 PolarHBondContact O-N 2.89Å
324	V	85.5	Confident	83.1	Confident	1 Å²	1	59.4 Å²	59.4	1%	0.006	33%	0.327	C	S	.	.	H	α-helix	trans	-66.1	-43.6	178.9	172.1	0	0	0	0	111.7	T320 M322 H326 E327 C328 F339 L346 V356 F360	T320-V324 PolarHBondContact O-N 2.89Å; M322-V324 VanDerWaalsContact C-N 3.34Å; M322-V324 PolarHBondContact O-N 2.7Å; V324-H326 VanDerWaalsContact C-N 3.26Å; V324-H326 PolarHBondContact O-N 2.96Å; V324-E327 PolarHBondContact O-N 3.48Å; V324-C328 WeakPolarHBondContact O-CB 3.48Å; V324-C328 PolarHBondContact O-N 2.93Å; V324-C328 PolarHBondContact O-SG 2.98Å; V324-C328 VanDerWaalsContact O-SG 3.33Å; V324-F339 HydrophobicContact CG1-CD1 4.02Å; V324-F339 HydrophobicContact CG1-CD2 3.95Å; V324-F339 HydrophobicContact CG1-CE1 4.13Å; V324-F339 HydrophobicContact CG1-CE2 4.04Å; V324-F339 HydrophobicContact CG1-CG 3.94Å; V324-F339 HydrophobicContact CG1-CZ 4.14Å; V324-L346 HydrophobicContact CG2-CD2 3.66Å; V324-V356 HydrophobicContact CG1-CG2 3.61Å; V324-F360 HydrophobicContact CB-CE2 4.41Å; V324-F360 HydrophobicContact CG1-CE2 4.35Å; V324-F360 HydrophobicContact CG2-CE2 3.97Å; V324-F360 HydrophobicContact CG2-CZ 4.21Å
325	N	85.8	Confident	82.1	Confident	19 Å²	19	59.1 Å²	59.1	10%	0.102	32%	0.322	C	S	.	.	H	α-helix	trans	-64.2	-33.3	179.9	-172.6	66.8	0	0	0	112.1	N321 M322 N329 F339 L341	N321-N325 VanDerWaalsContact O-CB 3.28Å; N321-N325 WeakPolarHBondContact O-CB 3.44Å; N321-N325 PolarHBondContact O-N 2.77Å; M322-N325 PolarHBondContact O-N 3.47Å; N325-N329 WeakPolarHBondContact O-CB 3.14Å; N325-N329 PolarHBondContact O-N 3.18Å; N325-F339 HydrophobicContact CB-CB 4.23Å; N325-L341 VanDerWaalsContact ND2-CD2 3.33Å; N325-L341 WeakPolarHBondContact ND2-CD2 3.48Å
326	H	85.1	Confident	81.1	Confident	131 Å²	131	63.3 Å²	63.3	61%	0.606	35%	0.347	S	S	*	.	H	α-helix	trans	-63.2	-48	174.1	-176.6	-90.8	0	0	0	111.9	M322 D323 V324 N329 A330	M322-H326 PolarHBondContact O-N 3.2Å; D323-H326 PolarHBondContact O-N 3Å; V324-H326 VanDerWaalsContact C-N 3.26Å; V324-H326 PolarHBondContact O-N 2.96Å; H326-N329 PolarHBondContact O-N 3.14Å; H326-A330 PolarHBondContact O-N 2.9Å; H326-A330 VanDerWaalsContact O-N 3.13Å
327	E	85.6	Confident	80.5	Confident	80 Å²	80	68.2 Å²	68.2	37%	0.374	37%	0.374	S	S	.	.	H	α-helix	trans	-66.5	-40	178	-64.5	-59.4	139.6	0	0	112.4	D323 V324 N329 A330 T331 F360	D323-E327 PolarHBondContact O-N 2.89Å; V324-E327 PolarHBondContact O-N 3.48Å; E327-N329 PolarHBondContact O-N 3.46Å; E327-A330 WeakPolarHBondContact O-CB 3.4Å; E327-A330 PolarHBondContact O-N 3.28Å; E327-T331 PolarHBondContact O-N 3.48Å; E327-T331 VanDerWaalsContact O-N 3.16Å; E327-T331 PolarHBondContact O-OG1 2.98Å; E327-F360 HydrophobicContact CB-CE1 4.3Å; E327-F360 HydrophobicContact CB-CE2 4.14Å; E327-F360 HydrophobicContact CB-CZ 4.02Å; E327-F360 HydrophobicContact CG-CD1 4.42Å; E327-F360 HydrophobicContact CG-CE1 3.77Å; E327-F360 HydrophobicContact CG-CE2 4.38Å; E327-F360 HydrophobicContact CG-CZ 3.76Å
328	C	84.9	Confident	80.1	Confident	1 Å²	1	65.7 Å²	65.7	1%	0.007	37%	0.365	C	S	.	.	H	α-helix	trans	-63.5	-39.6	176	-73.2	0	0	0	0	112.6	V324 A330 T331 G332 I333 C359	V324-C328 WeakPolarHBondContact O-CB 3.48Å; V324-C328 PolarHBondContact O-N 2.93Å; V324-C328 PolarHBondContact O-SG 2.98Å; V324-C328 VanDerWaalsContact O-SG 3.33Å; C328-A330 VanDerWaalsContact C-N 3.34Å; C328-T331 PolarHBondContact O-N 3.01Å; C328-T331 PolarHBondContact O-OG1 3.39Å; C328-T331 VanDerWaalsContact O-OG1 3.08Å; C328-G332 PolarHBondContact O-N 3.44Å; C328-I333 WeakPolarHBondContact CB-O 3.4Å; C328-I333 PolarHBondContact O-N 3.35Å; C328-C359 WeakPolarHBondContact CA-SG 3.27Å; C328-C359 HydrophobicContact CB-CB 3.89Å; C328-C359 WeakPolarHBondContact CB-SG 3.4Å; C328-C359 WeakPolarHBondContact SG-CB 3.45Å; C328-C359 CovalentContact SG-SG 2.04Å; C328-C359 PolarHBondContact SG-SG 3.46Å
329	N	84.1	Confident	79.9	Confident	96 Å²	96	59.6 Å²	59.6	51%	0.513	33%	0.333	S	S	.	.	H	α-helix	trans	-67.3	-37.1	176.2	-171.3	28.1	0	0	0	111.6	N325 H326 E327 T331 G332 N334	N325-N329 WeakPolarHBondContact O-CB 3.14Å; N325-N329 PolarHBondContact O-N 3.18Å; H326-N329 PolarHBondContact O-N 3.14Å; E327-N329 PolarHBondContact O-N 3.46Å; N329-T331 VanDerWaalsContact C-N 3.26Å; N329-T331 PolarHBondContact O-N 2.98Å; N329-G332 PolarHBondContact O-N 3.18Å; N329-N334 WeakPolarHBondContact CA-OD1 3.32Å; N329-N334 PolarHBondContact OD1-OD1 3.28Å
330	A	81.8	Confident	79.6	Confident	80 Å²	80	58.8 Å²	58.8	66%	0.661	34%	0.335	S	S	*	.	H	α-helix	trans	-62.6	-32.6	175.4	0	0	0	0	0	112.7	H326 E327 C328	H326-A330 PolarHBondContact O-N 2.9Å; H326-A330 VanDerWaalsContact O-N 3.13Å; E327-A330 WeakPolarHBondContact O-CB 3.4Å; E327-A330 PolarHBondContact O-N 3.28Å; C328-A330 VanDerWaalsContact C-N 3.34Å
331	T	76.8	Confident	79.2	Confident	72 Å²	72	63.9 Å²	63.9	44%	0.442	36%	0.361	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.6	-0.1	176.8	46.1	0	0	0	0	114.5	E327 C328 N329 C359	E327-T331 PolarHBondContact O-N 3.48Å; E327-T331 VanDerWaalsContact O-N 3.16Å; E327-T331 PolarHBondContact O-OG1 2.98Å; C328-T331 PolarHBondContact O-N 3.01Å; C328-T331 PolarHBondContact O-OG1 3.39Å; C328-T331 VanDerWaalsContact O-OG1 3.08Å; N329-T331 VanDerWaalsContact C-N 3.26Å; N329-T331 PolarHBondContact O-N 2.98Å; T331-C359 WeakPolarHBondContact CG2-O 3.29Å; T331-C359 PolarHBondContact OG1-O 3.28Å
332	G	72.3	Confident	79.1	Confident	61 Å²	61	66.4 Å²	66.4	63%	0.629	37%	0.374	S	S	*	.	T	Hydrogen-bonded Turn	trans	79.6	13.3	177.4	0	0	0	0	0	114.7	C328 N329	C328-G332 PolarHBondContact O-N 3.44Å; N329-G332 PolarHBondContact O-N 3.18Å
333	I	72.2	Confident	79	Confident	44 Å²	44	68.8 Å²	68.8	23%	0.226	39%	0.389	C	S	.	.			trans	-97.5	84.8	174.8	-56.2	176.4	0	0	0	108.1	C328 R335 V355	C328-I333 WeakPolarHBondContact CB-O 3.4Å; C328-I333 PolarHBondContact O-N 3.35Å; I333-R335 HydrophobicContact CG2-CG 4.03Å; I333-R335 PolarHBondContact O-N 3.26Å; I333-V355 HydrophobicContact CG2-CG1 4.46Å
334	N	68.5	Low	78.9	Confident	106 Å²	106	67.6 Å²	67.6	57%	0.567	39%	0.386	S	S	*	.			trans	-85.2	99.5	-177.7	-71.8	3	0	0	0	111.3	N329	N329-N334 WeakPolarHBondContact CA-OD1 3.32Å; N329-N334 PolarHBondContact OD1-OD1 3.28Å
335	R	71.1	Confident	78.7	Confident	79 Å²	79	72.8 Å²	72.8	30%	0.298	42%	0.418	S	S	.	.			trans	-126.8	63.1	179.5	-66.7	-69	-171.5	163.7	1.5	112.4	I333 D337 L338 F339	I333-R335 HydrophobicContact CG2-CG 4.03Å; I333-R335 PolarHBondContact O-N 3.26Å; R335-D337 WeakPolarHBondContact CA-OD1 3.24Å; R335-D337 PolarHBondContact O-N 2.96Å; R335-L338 HydrophobicContact CB-CB 4.21Å; R335-L338 HydrophobicContact CB-CD1 3.91Å; R335-L338 HydrophobicContact CB-CG 4.19Å; R335-L338 HydrophobicContact CG-CD1 4.02Å; R335-L338 PolarHBondContact O-N 3.22Å; R335-L338 VanDerWaalsContact O-N 3.11Å; R335-F339 PolarHBondContact O-N 3.09Å; R335-F339 VanDerWaalsContact O-N 3.15Å
336	T	65.7	Low	78.4	Confident	94 Å²	94	72.8 Å²	72.8	58%	0.577	42%	0.418	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.6	-16.6	177.8	53.6	0	0	0	0	113.4
337	D	72.8	Confident	78.1	Confident	109 Å²	109	73.1 Å²	73.1	58%	0.583	42%	0.42	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.3	-35.3	171.3	56.4	-37.5	0	0	0	112.5	R335	R335-D337 WeakPolarHBondContact CA-OD1 3.24Å; R335-D337 PolarHBondContact O-N 2.96Å
338	L	76.1	Confident	78	Confident	21 Å²	21	69.7 Å²	69.7	11%	0.11	40%	0.404	C	S	.	.	T	Hydrogen-bonded Turn	trans	-90.7	-37.1	-177.4	-60.8	176.3	0	0	0	112.8	R335 P340 Y351 V355	R335-L338 HydrophobicContact CB-CB 4.21Å; R335-L338 HydrophobicContact CB-CD1 3.91Å; R335-L338 HydrophobicContact CB-CG 4.19Å; R335-L338 HydrophobicContact CG-CD1 4.02Å; R335-L338 PolarHBondContact O-N 3.22Å; R335-L338 VanDerWaalsContact O-N 3.11Å; L338-P340 WeakPolarHBondContact O-CD 3.29Å; L338-Y351 HydrophobicContact CD1-CD1 4.47Å; L338-Y351 HydrophobicContact CD1-CE1 3.48Å; L338-Y351 VanDerWaalsContact CD1-CE1 3.48Å; L338-Y351 HydrophobicContact CD2-CD1 4.38Å; L338-Y351 HydrophobicContact CD2-CE1 3.66Å; L338-Y351 HydrophobicContact CG-CE1 4.22Å; L338-V355 HydrophobicContact CD1-CG2 4.31Å
339	F	81	Confident	78.1	Confident	0 Å²	0	69.8 Å²	69.8	0%	0	41%	0.405	C	S	.	.	S	Bend	trans	-120.2	85.9	179.9	-52.2	-64.6	0	0	0	109.5	V324 N325 R335 L346 K352 V355 V356	V324-F339 HydrophobicContact CG1-CD1 4.02Å; V324-F339 HydrophobicContact CG1-CD2 3.95Å; V324-F339 HydrophobicContact CG1-CE1 4.13Å; V324-F339 HydrophobicContact CG1-CE2 4.04Å; V324-F339 HydrophobicContact CG1-CG 3.94Å; V324-F339 HydrophobicContact CG1-CZ 4.14Å; N325-F339 HydrophobicContact CB-CB 4.23Å; R335-F339 PolarHBondContact O-N 3.09Å; R335-F339 VanDerWaalsContact O-N 3.15Å; F339-L346 HydrophobicContact CD1-CD1 3.7Å; F339-L346 HydrophobicContact CE1-CD1 3.68Å; F339-K352 HydrophobicContact CE1-CB 4.21Å; F339-K352 HydrophobicContact CE1-CG 4.26Å; F339-K352 HydrophobicContact CZ-CB 4.3Å; F339-K352 HydrophobicContact CZ-CG 4.49Å; F339-V355 HydrophobicContact CE2-CB 4.41Å; F339-V355 HydrophobicContact CE2-CG1 3.77Å; F339-V355 HydrophobicContact CZ-CB 4.41Å; F339-V355 HydrophobicContact CZ-CG1 4.25Å; F339-V356 HydrophobicContact CE1-CG2 3.85Å; F339-V356 HydrophobicContact CE2-CG2 4.24Å; F339-V356 HydrophobicContact CZ-CG2 3.47Å; F339-V356 VanDerWaalsContact CZ-CG2 3.47Å
340	P	79.9	Confident	78.3	Confident	60 Å²	60	65.3 Å²	65.3	39%	0.39	38%	0.381	S	S	.	.			trans	-62.4	148.3	178.3	25.5	-33.3	0	0	0	110.5	N321 L338 N342	N321-P340 WeakPolarHBondContact CB-O 3.35Å; L338-P340 WeakPolarHBondContact O-CD 3.29Å; P340-N342 PolarHBondContact O-N 3.35Å; P340-N342 PolarHBondContact O-OD1 3.07Å
341	L	80.1	Confident	78.7	Confident	130 Å²	130	62.2 Å²	62.2	68%	0.681	35%	0.352	S	S	*	.	S	Bend	trans	-72.6	66.7	177.1	-72.6	164.6	0	0	0	111.4	N325	N325-L341 VanDerWaalsContact ND2-CD2 3.33Å; N325-L341 WeakPolarHBondContact ND2-CD2 3.48Å
342	N	82.8	Confident	79.2	Confident	63 Å²	63	59.6 Å²	59.6	34%	0.337	33%	0.334	S	S	.	.	S	Bend	trans	-129	157.9	176.8	67.8	1.1	0	0	0	111.4	N321 M322 P340 S344	N321-N342 WeakPolarHBondContact CB-OD1 3.49Å; N321-N342 PolarHBondContact ND2-OD1 3.48Å; M322-N342 WeakPolarHBondContact CG-O 3.31Å; P340-N342 PolarHBondContact O-N 3.35Å; P340-N342 PolarHBondContact O-OD1 3.07Å; N342-S344 PolarHBondContact ND2-OG 3.29Å; N342-S344 PolarHBondContact O-N 3.27Å; N342-S344 PolarHBondContact OD1-OG 3.06Å
343	N	82.6	Confident	80	Confident	124 Å²	124	56.7 Å²	56.7	66%	0.663	31%	0.305	S	S	*	.			trans	-88.6	23	-179.2	-151.6	23	0	0	0	112.7	M322	M322-N343 HydrophobicContact CE-CB 3.68Å; M322-N343 WeakPolarHBondContact CE-OD1 3.4Å
344	S	83.1	Confident	80.8	Confident	48 Å²	48	54.6 Å²	54.6	34%	0.336	29%	0.294	S	S	.	.	S	Bend	trans	-78.8	151	175.4	59.7	0	0	0	0	110.2	N321 N342	N321-S344 PolarHBondContact N-O 3.35Å; N321-S344 PolarHBondContact ND2-OG 3.3Å; N342-S344 PolarHBondContact ND2-OG 3.29Å; N342-S344 PolarHBondContact O-N 3.27Å; N342-S344 PolarHBondContact OD1-OG 3.06Å
345	T	80.6	Confident	81.8	Confident	110 Å²	110	49.9 Å²	49.9	68%	0.675	27%	0.269	S	S	*	.	B	Isolated β-bridge	trans	-57.8	137.2	169.1	46.7	0	0	0	0	109.9	E347	T345-E347 PolarHBondContact O-N 3.46Å
346	L	79.3	Confident	82.7	Confident	19 Å²	19	46.1 Å²	46.1	10%	0.099	26%	0.255	C	S	.	.	P	Polyproline II helix	trans	-68.3	122.9	-179.7	172.9	60	0	0	0	110.8	F316 K319 N321 V324 F339 V348 V356	F316-L346 HydrophobicContact CD1-CD2 3.48Å; F316-L346 VanDerWaalsContact CD1-CD2 3.48Å; F316-L346 HydrophobicContact CD1-CG 4.31Å; F316-L346 HydrophobicContact CE1-CD2 3.84Å; K319-L346 PolarHBondContact O-N 2.97Å; N321-L346 WeakPolarHBondContact OD1-CD1 3.38Å; V324-L346 HydrophobicContact CG2-CD2 3.66Å; F339-L346 HydrophobicContact CD1-CD1 3.7Å; F339-L346 HydrophobicContact CE1-CD1 3.68Å; L346-V348 HydrophobicContact CG-CG2 4.13Å; L346-V356 HydrophobicContact CD2-CG2 4.36Å
347	E	79.1	Confident	83.9	Confident	139 Å²	139	41.7 Å²	41.7	65%	0.65	23%	0.227	S	C	*	.	P	Polyproline II helix	trans	-80.8	126.4	166.7	-70	-180	174.9	0	0	109.1	T345 K352	T345-E347 PolarHBondContact O-N 3.46Å; E347-K352 WeakPolarHBondContact O-CD 3.45Å
348	V	82.2	Confident	84.6	Confident	7 Å²	7	36.5 Å²	36.5	4%	0.042	20%	0.199	C	C	.	.			trans	-109.6	135.8	-174.8	-166.8	0	0	0	0	109.2	L88 A92 F312 F316 L346	L88-V348 HydrophobicContact CD1-CB 4.01Å; L88-V348 HydrophobicContact CD1-CG1 3.41Å; L88-V348 VanDerWaalsContact CD1-CG1 3.41Å; A92-V348 HydrophobicContact CB-CB 3.95Å; A92-V348 HydrophobicContact CB-CG2 3.45Å; A92-V348 VanDerWaalsContact CB-CG2 3.45Å; F312-V348 HydrophobicContact CD1-CG1 3.99Å; F312-V348 HydrophobicContact CE1-CG1 4.13Å; F316-V348 HydrophobicContact CB-CG2 4.16Å; F316-V348 HydrophobicContact CD1-CB 4.28Å; F316-V348 HydrophobicContact CD1-CG1 3.89Å; F316-V348 HydrophobicContact CD1-CG2 3.28Å; F316-V348 HydrophobicContact CE1-CB 4.43Å; F316-V348 HydrophobicContact CE1-CG1 3.67Å; F316-V348 HydrophobicContact CE1-CG2 3.84Å; F316-V348 HydrophobicContact CG-CG1 4.49Å; F316-V348 HydrophobicContact CG-CG2 3.96Å; F316-V348 HydrophobicContact CZ-CG1 4.14Å; L346-V348 HydrophobicContact CG-CG2 4.13Å
349	D	87.8	Confident	85.2	Confident	4 Å²	4	35.5 Å²	35.5	2%	0.021	20%	0.195	C	C	.	.			trans	-137.9	171.8	170	56.8	52.6	0	0	0	110	E85 Y351 K352 G353 T430	E85-D349 WeakPolarHBondContact OE1-CA 3.33Å; D349-Y351 PolarHBondContact O-N 2.91Å; D349-Y351 VanDerWaalsContact O-N 3.12Å; D349-Y351 WeakPolarHBondContact OD1-CA 3.3Å; D349-Y351 WeakPolarHBondContact OD1-CB 3.38Å; D349-Y351 PolarHBondContact OD1-N 2.86Å; D349-K352 PolarHBondContact O-N 3.15Å; D349-K352 WeakPolarHBondContact OD1-CB 3.32Å; D349-K352 WeakPolarHBondContact OD1-CG 3.48Å; D349-K352 PolarHBondContact OD1-N 3.43Å; D349-K352 WeakPolarHBondContact OD2-CD 3.44Å; D349-K352 WeakPolarHBondContact OD2-CE 3.11Å; D349-K352 IonicContact OD2-NZ 3.55Å; D349-G353 WeakPolarHBondContact O-CA 3.47Å; D349-G353 PolarHBondContact O-N 2.91Å; D349-T430 HydrophobicContact CB-CG2 3.51Å; D349-T430 WeakPolarHBondContact OD2-CG2 3.26Å; D349-T430 PolarHBondContact OD2-OG1 2.87Å
350	I	89.3	Confident	85.6	Confident	1 Å²	1	38.4 Å²	38.4	1%	0.005	21%	0.207	C	C	.	.	H	α-helix	trans	-51	-37.6	178.7	-72.3	156.4	0	0	0	112.4	P81 E85 L88 I164 G354 W369 I373	P81-I350 HydrophobicContact CB-CD1 4.1Å; E85-I350 HydrophobicContact CB-CD1 4.09Å; E85-I350 HydrophobicContact CB-CG1 4.34Å; E85-I350 WeakPolarHBondContact OE2-CD1 3.17Å; E85-I350 WeakPolarHBondContact OE2-CG1 3.5Å; E85-I350 PolarHBondContact OE2-N 3.32Å; L88-I350 HydrophobicContact CD2-CB 4.46Å; L88-I350 HydrophobicContact CD2-CG1 3.73Å; I164-I350 HydrophobicContact CD1-CB 4.5Å; I164-I350 HydrophobicContact CG2-CG2 3.79Å; I350-G354 PolarHBondContact O-N 3.17Å; I350-W369 HydrophobicContact CG2-CZ2 4.42Å; I350-W369 PolarHBondContact O-NE1 3.41Å; I350-I373 HydrophobicContact CG1-CD1 4.37Å; I350-I373 HydrophobicContact CG2-CD1 3.93Å; I350-I373 HydrophobicContact CG2-CG1 3.88Å; I350-I373 HydrophobicContact CG2-CG2 3.91Å
351	Y	88.9	Confident	86	Confident	16 Å²	16	38.8 Å²	38.8	6%	0.063	20%	0.203	C	C	.	.	H	α-helix	trans	-74.8	-55.9	-176.4	177.3	-101.3	0	0	0	111.6	I164 N167 L168 L338 D349 G353 G354 V355 V426	I164-Y351 HydrophobicContact CG2-CD2 4.08Å; I164-Y351 HydrophobicContact CG2-CG 4.44Å; N167-Y351 VanDerWaalsContact OD1-CE2 3.24Å; N167-Y351 WeakPolarHBondContact OD1-CE2 3.49Å; L168-Y351 HydrophobicContact CD1-CD2 4.46Å; L168-Y351 HydrophobicContact CD2-CD2 3.62Å; L168-Y351 HydrophobicContact CD2-CE2 3.55Å; L168-Y351 HydrophobicContact CG-CD2 3.9Å; L168-Y351 HydrophobicContact CG-CE2 4.14Å; L338-Y351 HydrophobicContact CD1-CD1 4.47Å; L338-Y351 HydrophobicContact CD1-CE1 3.48Å; L338-Y351 VanDerWaalsContact CD1-CE1 3.48Å; L338-Y351 HydrophobicContact CD2-CD1 4.38Å; L338-Y351 HydrophobicContact CD2-CE1 3.66Å; L338-Y351 HydrophobicContact CG-CE1 4.22Å; D349-Y351 PolarHBondContact O-N 2.91Å; D349-Y351 VanDerWaalsContact O-N 3.12Å; D349-Y351 WeakPolarHBondContact OD1-CA 3.3Å; D349-Y351 WeakPolarHBondContact OD1-CB 3.38Å; D349-Y351 PolarHBondContact OD1-N 2.86Å; Y351-G353 PolarHBondContact O-N 3.23Å; Y351-G354 PolarHBondContact O-N 3.39Å; Y351-V355 HydrophobicContact CE1-CG2 4.38Å; Y351-V355 WeakPolarHBondContact O-CG2 3.43Å; Y351-V355 PolarHBondContact O-N 3.22Å; Y351-V355 VanDerWaalsContact O-N 3.17Å; Y351-V426 HydrophobicContact CD1-CG1 4.08Å; Y351-V426 HydrophobicContact CG-CG1 4.35Å
352	K	88.1	Confident	86.4	Confident	17 Å²	17	33.4 Å²	33.4	7%	0.074	18%	0.179	C	C	.	.	H	α-helix	trans	-57.8	-36.9	174.7	-69	175.5	-170.8	162.7	0	110.7	F339 E347 D349 V355 V356	F339-K352 HydrophobicContact CE1-CB 4.21Å; F339-K352 HydrophobicContact CE1-CG 4.26Å; F339-K352 HydrophobicContact CZ-CB 4.3Å; F339-K352 HydrophobicContact CZ-CG 4.49Å; E347-K352 WeakPolarHBondContact O-CD 3.45Å; D349-K352 PolarHBondContact O-N 3.15Å; D349-K352 WeakPolarHBondContact OD1-CB 3.32Å; D349-K352 WeakPolarHBondContact OD1-CG 3.48Å; D349-K352 PolarHBondContact OD1-N 3.43Å; D349-K352 WeakPolarHBondContact OD2-CD 3.44Å; D349-K352 WeakPolarHBondContact OD2-CE 3.11Å; D349-K352 IonicContact OD2-NZ 3.55Å; K352-V355 PolarHBondContact O-N 3.17Å; K352-V356 WeakPolarHBondContact O-CG2 3.39Å; K352-V356 PolarHBondContact O-N 3.43Å
353	G	88.4	Confident	86.7	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-55.7	-52.9	177	0	0	0	0	0	112.5	D349 Y351 V355 V356 L357	D349-G353 WeakPolarHBondContact O-CA 3.47Å; D349-G353 PolarHBondContact O-N 2.91Å; Y351-G353 PolarHBondContact O-N 3.23Å; G353-V355 PolarHBondContact O-N 3.08Å; G353-V356 PolarHBondContact O-N 3.49Å; G353-L357 WeakPolarHBondContact O-CG 2.97Å; G353-L357 PolarHBondContact O-N 3Å
354	G	89.9	Confident	87.2	Confident	0 Å²	0	31.1 Å²	31.1	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-62.7	-38.7	176.6	0	0	0	0	0	113.6	I350 Y351 G358 L366	I350-G354 PolarHBondContact O-N 3.17Å; Y351-G354 PolarHBondContact O-N 3.39Å; G354-G358 PolarHBondContact O-N 2.97Å; G354-L366 WeakPolarHBondContact O-CG 3.48Å
355	V	89	Confident	87.6	Confident	6 Å²	6	28.8 Å²	28.8	4%	0.036	16%	0.162	C	C	.	.	H	α-helix	trans	-65.1	-45.9	178	178.4	0	0	0	0	111.2	L168 I333 L338 F339 Y351 K352 G353 G358 C359	L168-V355 HydrophobicContact CD2-CG2 4.05Å; I333-V355 HydrophobicContact CG2-CG1 4.46Å; L338-V355 HydrophobicContact CD1-CG2 4.31Å; F339-V355 HydrophobicContact CE2-CB 4.41Å; F339-V355 HydrophobicContact CE2-CG1 3.77Å; F339-V355 HydrophobicContact CZ-CB 4.41Å; F339-V355 HydrophobicContact CZ-CG1 4.25Å; Y351-V355 HydrophobicContact CE1-CG2 4.38Å; Y351-V355 WeakPolarHBondContact O-CG2 3.43Å; Y351-V355 PolarHBondContact O-N 3.22Å; Y351-V355 VanDerWaalsContact O-N 3.17Å; K352-V355 PolarHBondContact O-N 3.17Å; G353-V355 PolarHBondContact O-N 3.08Å; V355-G358 CarbonylContact O-C 3.57Å; V355-G358 WeakPolarHBondContact O-CA 3.2Å; V355-G358 PolarHBondContact O-N 3.08Å; V355-G358 VanDerWaalsContact O-N 3.13Å; V355-C359 PolarHBondContact O-N 2.95Å; V355-C359 PolarHBondContact O-SG 3.05Å
356	V	89.2	Confident	88.2	Confident	1 Å²	1	24.7 Å²	24.7	1%	0.006	14%	0.136	C	C	.	.	H	α-helix	trans	-64.7	-43	178.4	169.4	0	0	0	0	111.3	F316 V324 F339 L346 K352 G353 G358 C359 F360	F316-V356 HydrophobicContact CD1-CG1 4.29Å; F316-V356 HydrophobicContact CE1-CB 3.59Å; F316-V356 HydrophobicContact CE1-CG1 3.56Å; F316-V356 HydrophobicContact CE1-CG2 3.61Å; F316-V356 HydrophobicContact CE2-CB 4.24Å; F316-V356 HydrophobicContact CE2-CG1 3.77Å; F316-V356 HydrophobicContact CZ-CB 3.32Å; F316-V356 HydrophobicContact CZ-CG1 3.27Å; F316-V356 HydrophobicContact CZ-CG2 3.91Å; V324-V356 HydrophobicContact CG1-CG2 3.61Å; F339-V356 HydrophobicContact CE1-CG2 3.85Å; F339-V356 HydrophobicContact CE2-CG2 4.24Å; F339-V356 HydrophobicContact CZ-CG2 3.47Å; F339-V356 VanDerWaalsContact CZ-CG2 3.47Å; L346-V356 HydrophobicContact CD2-CG2 4.36Å; K352-V356 WeakPolarHBondContact O-CG2 3.39Å; K352-V356 PolarHBondContact O-N 3.43Å; G353-V356 PolarHBondContact O-N 3.49Å; V356-G358 PolarHBondContact O-N 3.22Å; V356-C359 PolarHBondContact O-N 3.34Å; V356-F360 HydrophobicContact CG1-CD2 3.53Å; V356-F360 HydrophobicContact CG1-CE2 3.67Å; V356-F360 WeakPolarHBondContact O-CD2 3.28Å; V356-F360 PolarHBondContact O-N 3.15Å
357	L	90.7	Very high	88.9	Confident	0 Å²	0	28.4 Å²	28.4	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-56	-40.8	172.7	-70.9	174	0	0	0	111.2	V223 V311 F312 G353 C359 F361 A365 W369	V223-L357 HydrophobicContact CG2-CD2 4.44Å; V311-L357 HydrophobicContact CG1-CD2 3.77Å; F312-L357 HydrophobicContact CE2-CD1 4.35Å; F312-L357 HydrophobicContact CZ-CD1 3.9Å; F312-L357 HydrophobicContact CZ-CG 4.44Å; G353-L357 WeakPolarHBondContact O-CG 2.97Å; G353-L357 PolarHBondContact O-N 3Å; L357-C359 PolarHBondContact O-N 2.85Å; L357-F361 HydrophobicContact CD2-CD2 4.01Å; L357-F361 HydrophobicContact CD2-CE2 4.19Å; L357-F361 WeakPolarHBondContact O-CB 3.46Å; L357-F361 PolarHBondContact O-N 2.96Å; L357-A365 HydrophobicContact CB-CB 4.25Å; L357-W369 HydrophobicContact CD1-CB 4.21Å; L357-W369 HydrophobicContact CD1-CD2 4.02Å; L357-W369 HydrophobicContact CD1-CE3 3.94Å; L357-W369 HydrophobicContact CD1-CG 4.15Å
358	G	89.2	Confident	89.8	Confident	0 Å²	0	23.9 Å²	23.9	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-58.7	-43	171.8	0	0	0	0	0	114.5	G354 V355 V356 G362	G354-G358 PolarHBondContact O-N 2.97Å; V355-G358 CarbonylContact O-C 3.57Å; V355-G358 WeakPolarHBondContact O-CA 3.2Å; V355-G358 PolarHBondContact O-N 3.08Å; V355-G358 VanDerWaalsContact O-N 3.13Å; V356-G358 PolarHBondContact O-N 3.22Å; G358-G362 WeakPolarHBondContact CA-O 3.49Å; G358-G362 CarbonylContact O-C 3.59Å; G358-G362 WeakPolarHBondContact O-CA 3.27Å; G358-G362 PolarHBondContact O-N 3.41Å
359	C	88.5	Confident	90.4	Very high	1 Å²	1	23.7 Å²	23.7	1%	0.007	13%	0.128	C	C	.	.	H	α-helix	trans	-71.1	-41.5	-179.9	-63.4	0	0	0	0	113	C328 T331 V355 V356 L357	C328-C359 WeakPolarHBondContact CA-SG 3.27Å; C328-C359 HydrophobicContact CB-CB 3.89Å; C328-C359 WeakPolarHBondContact CB-SG 3.4Å; C328-C359 WeakPolarHBondContact SG-CB 3.45Å; C328-C359 CovalentContact SG-SG 2.04Å; C328-C359 PolarHBondContact SG-SG 3.46Å; T331-C359 WeakPolarHBondContact CG2-O 3.29Å; T331-C359 PolarHBondContact OG1-O 3.28Å; V355-C359 PolarHBondContact O-N 2.95Å; V355-C359 PolarHBondContact O-SG 3.05Å; V356-C359 PolarHBondContact O-N 3.34Å; L357-C359 PolarHBondContact O-N 2.85Å
360	F	88.4	Confident	90.8	Very high	60 Å²	60	23.5 Å²	23.5	26%	0.263	13%	0.127	S	C	.	.	H	α-helix	trans	-84.8	-36.6	-174.9	-80.3	-99.2	0	0	0	112.9	V324 E327 V356	V324-F360 HydrophobicContact CB-CE2 4.41Å; V324-F360 HydrophobicContact CG1-CE2 4.35Å; V324-F360 HydrophobicContact CG2-CE2 3.97Å; V324-F360 HydrophobicContact CG2-CZ 4.21Å; E327-F360 HydrophobicContact CB-CE1 4.3Å; E327-F360 HydrophobicContact CB-CE2 4.14Å; E327-F360 HydrophobicContact CB-CZ 4.02Å; E327-F360 HydrophobicContact CG-CD1 4.42Å; E327-F360 HydrophobicContact CG-CE1 3.77Å; E327-F360 HydrophobicContact CG-CE2 4.38Å; E327-F360 HydrophobicContact CG-CZ 3.76Å; V356-F360 HydrophobicContact CG1-CD2 3.53Å; V356-F360 HydrophobicContact CG1-CE2 3.67Å; V356-F360 WeakPolarHBondContact O-CD2 3.28Å; V356-F360 PolarHBondContact O-N 3.15Å
361	F	89.3	Confident	91.1	Very high	68 Å²	68	26.4 Å²	26.4	30%	0.298	15%	0.145	S	C	.	.	H	α-helix	trans	-119.4	0.7	-170.1	-54.5	-79.4	0	0	0	113.3	L222 V223 A315 L357 A365	L222-F361 HydrophobicContact CD2-CB 3.64Å; L222-F361 HydrophobicContact CD2-CG 4.34Å; L222-F361 HydrophobicContact CG-CB 4.11Å; L222-F361 HydrophobicContact CG-CD1 4.15Å; L222-F361 HydrophobicContact CG-CG 4.39Å; V223-F361 HydrophobicContact CB-CE1 4.32Å; V223-F361 HydrophobicContact CB-CZ 4.11Å; V223-F361 HydrophobicContact CG1-CZ 3.99Å; V223-F361 HydrophobicContact CG2-CD1 4.37Å; V223-F361 HydrophobicContact CG2-CD2 4.07Å; V223-F361 HydrophobicContact CG2-CE1 3.98Å; V223-F361 HydrophobicContact CG2-CE2 3.68Å; V223-F361 HydrophobicContact CG2-CG 4.41Å; V223-F361 HydrophobicContact CG2-CZ 3.63Å; A315-F361 HydrophobicContact CB-CE2 4.18Å; L357-F361 HydrophobicContact CD2-CD2 4.01Å; L357-F361 HydrophobicContact CD2-CE2 4.19Å; L357-F361 WeakPolarHBondContact O-CB 3.46Å; L357-F361 PolarHBondContact O-N 2.96Å; F361-A365 HydrophobicContact CB-CB 4.06Å
362	G	88.9	Confident	91.5	Very high	18 Å²	18	25.7 Å²	25.7	19%	0.186	14%	0.142	C	C	.	.			trans	97.5	167.4	174.3	0	0	0	0	0	114	G358 A364 A365	G358-G362 WeakPolarHBondContact CA-O 3.49Å; G358-G362 CarbonylContact O-C 3.59Å; G358-G362 WeakPolarHBondContact O-CA 3.27Å; G358-G362 PolarHBondContact O-N 3.41Å; G362-A364 PolarHBondContact O-N 3.02Å; G362-A364 VanDerWaalsContact O-N 3.1Å; G362-A365 WeakPolarHBondContact O-CB 3.35Å; G362-A365 PolarHBondContact O-N 3.44Å; G362-A365 VanDerWaalsContact O-N 3.09Å
363	P	88.8	Confident	91.9	Very high	87 Å²	87	24.9 Å²	24.9	57%	0.565	14%	0.138	S	C	*	.	H	α-helix	trans	-62.8	-25.5	-170.8	24.7	-34.9	0	0	0	113.7	A365 L366 Y367	P363-A365 VanDerWaalsContact C-N 3.32Å; P363-A365 PolarHBondContact O-N 3.04Å; P363-L366 PolarHBondContact O-N 3.28Å; P363-Y367 HydrophobicContact CB-CE2 4.37Å; P363-Y367 WeakPolarHBondContact O-CD2 3.29Å; P363-Y367 PolarHBondContact O-N 2.78Å
364	A	91.8	Very high	92.2	Very high	51 Å²	51	26.6 Å²	26.6	42%	0.421	15%	0.147	S	C	.	.	H	α-helix	trans	-61.4	-40.1	176.8	0	0	0	0	0	112.1	G362 L366 Y367 I368	G362-A364 PolarHBondContact O-N 3.02Å; G362-A364 VanDerWaalsContact O-N 3.1Å; A364-L366 VanDerWaalsContact C-N 3.35Å; A364-L366 PolarHBondContact O-N 2.94Å; A364-Y367 PolarHBondContact O-N 2.93Å; A364-I368 WeakPolarHBondContact O-CB 3.36Å; A364-I368 VanDerWaalsContact O-CG1 3.26Å; A364-I368 WeakPolarHBondContact O-CG1 3.45Å; A364-I368 PolarHBondContact O-N 3.11Å
365	A	92.6	Very high	92.4	Very high	0 Å²	0	26.9 Å²	26.9	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-63.1	-41.8	179.1	0	0	0	0	0	111.6	E219 L222 L357 F361 G362 P363 Y367 I368 W369	E219-A365 WeakPolarHBondContact OE1-CA 3.15Å; E219-A365 WeakPolarHBondContact OE1-CB 3.16Å; E219-A365 VanDerWaalsContact OE1-O 3.04Å; E219-A365 WeakPolarHBondContact OE2-CB 3.41Å; L222-A365 HydrophobicContact CD2-CB 4.15Å; L357-A365 HydrophobicContact CB-CB 4.25Å; F361-A365 HydrophobicContact CB-CB 4.06Å; G362-A365 WeakPolarHBondContact O-CB 3.35Å; G362-A365 PolarHBondContact O-N 3.44Å; G362-A365 VanDerWaalsContact O-N 3.09Å; P363-A365 VanDerWaalsContact C-N 3.32Å; P363-A365 PolarHBondContact O-N 3.04Å; A365-Y367 PolarHBondContact O-N 3.48Å; A365-I368 PolarHBondContact O-N 3.16Å; A365-W369 VanDerWaalsContact O-CB 3.29Å; A365-W369 WeakPolarHBondContact O-CB 3.45Å; A365-W369 PolarHBondContact O-N 3.21Å
366	L	92.7	Very high	92.7	Very high	24 Å²	24	26.6 Å²	26.6	13%	0.126	15%	0.148	C	C	.	.	H	α-helix	trans	-58.2	-47.4	174.9	-177.3	159.1	0	0	0	112.1	L168 G354 P363 A364 A370	L168-L366 HydrophobicContact CB-CD2 4.28Å; G354-L366 WeakPolarHBondContact O-CG 3.48Å; P363-L366 PolarHBondContact O-N 3.28Å; A364-L366 VanDerWaalsContact C-N 3.35Å; A364-L366 PolarHBondContact O-N 2.94Å; L366-A370 WeakPolarHBondContact O-CB 3.16Å; L366-A370 PolarHBondContact O-N 3.01Å
367	Y	94.8	Very high	92.9	Very high	97 Å²	97	26.6 Å²	26.6	38%	0.38	15%	0.148	S	C	.	.	H	α-helix	trans	-69	-39	-179.5	-68.6	-63.1	0	0	0	112.2	L169 V171 P363 A364 A365 A370 V371	L169-Y367 HydrophobicContact CD2-CD1 4.17Å; V171-Y367 HydrophobicContact CG2-CE1 4.28Å; V171-Y367 WeakPolarHBondContact CG2-OH 3.5Å; P363-Y367 HydrophobicContact CB-CE2 4.37Å; P363-Y367 WeakPolarHBondContact O-CD2 3.29Å; P363-Y367 PolarHBondContact O-N 2.78Å; A364-Y367 PolarHBondContact O-N 2.93Å; A365-Y367 PolarHBondContact O-N 3.48Å; Y367-A370 PolarHBondContact O-N 3.35Å; Y367-V371 WeakPolarHBondContact O-CG2 3.23Å; Y367-V371 PolarHBondContact O-N 2.83Å
368	I	96.3	Very high	92.9	Very high	44 Å²	44	28.3 Å²	28.3	23%	0.226	16%	0.156	C	C	.	.	H	α-helix	trans	-65.1	-43.3	177.9	-70.3	168.6	0	0	0	110.6	S215 Y218 A364 A365 V371 G372	S215-I368 WeakPolarHBondContact O-CG2 3.42Å; S215-I368 PolarHBondContact OG-O 3.01Å; Y218-I368 HydrophobicContact CD1-CD1 3.42Å; Y218-I368 VanDerWaalsContact CD1-CD1 3.42Å; Y218-I368 HydrophobicContact CD1-CG2 4.16Å; Y218-I368 HydrophobicContact CE1-CD1 3.38Å; Y218-I368 HydrophobicContact CG-CD1 4.07Å; A364-I368 WeakPolarHBondContact O-CB 3.36Å; A364-I368 VanDerWaalsContact O-CG1 3.26Å; A364-I368 WeakPolarHBondContact O-CG1 3.45Å; A364-I368 PolarHBondContact O-N 3.11Å; A365-I368 PolarHBondContact O-N 3.16Å; I368-V371 PolarHBondContact O-N 3.33Å; I368-G372 PolarHBondContact O-N 3.04Å
369	W	95.8	Very high	92.9	Very high	3 Å²	3	28.3 Å²	28.3	1%	0.011	16%	0.156	C	C	.	.	H	α-helix	trans	-54.4	-52.4	170.1	176.2	-103.5	0	0	0	111.3	I84 L88 F216 V308 F312 I350 L357 A365 V371 G372 I373	I84-W369 HydrophobicContact CG2-CH2 3.71Å; I84-W369 HydrophobicContact CG2-CZ2 4.28Å; L88-W369 HydrophobicContact CD2-CH2 4.26Å; L88-W369 HydrophobicContact CD2-CZ2 4.07Å; F216-W369 AromaticContact CD1-CE3 3.8Å; F216-W369 HydrophobicContact CD1-CE3 3.8Å; F216-W369 AromaticContact CD1-CZ3 3.68Å; F216-W369 HydrophobicContact CD1-CZ3 3.68Å; F216-W369 HydrophobicContact CE1-CD2 4.37Å; F216-W369 AromaticContact CE1-CE3 3.52Å; F216-W369 HydrophobicContact CE1-CE3 3.52Å; F216-W369 HydrophobicContact CE1-CH2 4.26Å; F216-W369 AromaticContact CE1-CZ3 3.43Å; F216-W369 HydrophobicContact CE1-CZ3 3.43Å; F216-W369 VanDerWaalsContact CE1-CZ3 3.43Å; F216-W369 HydrophobicContact CZ-CZ3 4.47Å; V308-W369 HydrophobicContact CG1-CH2 4.32Å; F312-W369 HydrophobicContact CD2-CH2 4.49Å; F312-W369 HydrophobicContact CE2-CE3 4.18Å; F312-W369 AromaticContact CE2-CH2 3.37Å; F312-W369 HydrophobicContact CE2-CH2 3.37Å; F312-W369 HydrophobicContact CE2-CZ2 4.05Å; F312-W369 AromaticContact CE2-CZ3 3.45Å; F312-W369 HydrophobicContact CE2-CZ3 3.45Å; F312-W369 VanDerWaalsContact CE2-CZ3 3.45Å; F312-W369 HydrophobicContact CZ-CE3 4.31Å; F312-W369 AromaticContact CZ-CH2 3.59Å; F312-W369 HydrophobicContact CZ-CH2 3.59Å; F312-W369 AromaticContact CZ-CZ2 3.77Å; F312-W369 HydrophobicContact CZ-CZ2 3.77Å; F312-W369 AromaticContact CZ-CZ3 3.88Å; F312-W369 HydrophobicContact CZ-CZ3 3.88Å; I350-W369 HydrophobicContact CG2-CZ2 4.42Å; I350-W369 PolarHBondContact O-NE1 3.41Å; L357-W369 HydrophobicContact CD1-CB 4.21Å; L357-W369 HydrophobicContact CD1-CD2 4.02Å; L357-W369 HydrophobicContact CD1-CE3 3.94Å; L357-W369 HydrophobicContact CD1-CG 4.15Å; A365-W369 VanDerWaalsContact O-CB 3.29Å; A365-W369 WeakPolarHBondContact O-CB 3.45Å; A365-W369 PolarHBondContact O-N 3.21Å; W369-V371 VanDerWaalsContact C-N 3.33Å; W369-V371 PolarHBondContact O-N 3.41Å; W369-G372 PolarHBondContact O-N 3.23Å; W369-G372 VanDerWaalsContact O-N 3.08Å; W369-I373 HydrophobicContact CD2-CG1 4.21Å; W369-I373 HydrophobicContact CG-CG1 4.48Å; W369-I373 HydrophobicContact CH2-CD1 4.07Å; W369-I373 HydrophobicContact CZ2-CD1 3.7Å; W369-I373 HydrophobicContact CZ2-CG1 4.09Å; W369-I373 WeakPolarHBondContact O-CG1 3.37Å; W369-I373 PolarHBondContact O-N 2.97Å
370	A	95.9	Very high	92.9	Very high	0 Å²	0	28.2 Å²	28.2	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-63.2	-36.2	-178.5	0	0	0	0	0	113	A165 L168 L169 L366 Y367 L374	A165-A370 WeakPolarHBondContact CB-O 3.36Å; L168-A370 HydrophobicContact CB-CB 3.78Å; L168-A370 HydrophobicContact CD1-CB 4.3Å; L169-A370 HydrophobicContact CD2-CB 3.78Å; L169-A370 HydrophobicContact CG-CB 3.77Å; L366-A370 WeakPolarHBondContact O-CB 3.16Å; L366-A370 PolarHBondContact O-N 3.01Å; Y367-A370 PolarHBondContact O-N 3.35Å; A370-L374 WeakPolarHBondContact O-CB 3.16Å; A370-L374 PolarHBondContact O-N 3.34Å
371	V	96.8	Very high	92.8	Very high	62 Å²	62	25.5 Å²	25.5	38%	0.376	14%	0.144	S	C	.	.	H	α-helix	trans	-64.8	-41.9	172.3	170.2	0	0	0	0	111.4	L169 V211 Y367 I368 W369 L374 A375	L169-V371 HydrophobicContact CD2-CG2 3.99Å; V211-V371 HydrophobicContact CG1-CG1 3.8Å; Y367-V371 WeakPolarHBondContact O-CG2 3.23Å; Y367-V371 PolarHBondContact O-N 2.83Å; I368-V371 PolarHBondContact O-N 3.33Å; W369-V371 VanDerWaalsContact C-N 3.33Å; W369-V371 PolarHBondContact O-N 3.41Å; V371-L374 PolarHBondContact O-N 3.01Å; V371-A375 PolarHBondContact O-N 2.8Å
372	G	96.6	Very high	92.5	Very high	0 Å²	0	22.3 Å²	22.3	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-61	-46.8	176.1	0	0	0	0	0	112.2	I368 W369 L374 A375 A376	I368-G372 PolarHBondContact O-N 3.04Å; W369-G372 PolarHBondContact O-N 3.23Å; W369-G372 VanDerWaalsContact O-N 3.08Å; G372-L374 PolarHBondContact O-N 3.15Å; G372-A375 PolarHBondContact O-N 3.33Å; G372-A376 PolarHBondContact O-N 3.27Å
373	I	95.7	Very high	92.3	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-64.3	-39	176.5	-61.6	-63.5	0	0	0	111.8	I84 G161 A165 F216 I350 W369 A376 G377	I84-I373 HydrophobicContact CB-CD1 4.46Å; I84-I373 HydrophobicContact CD1-CD1 4.12Å; I84-I373 HydrophobicContact CG2-CD1 3.67Å; G161-I373 WeakPolarHBondContact O-CG2 3.44Å; A165-I373 HydrophobicContact CB-CB 4.31Å; A165-I373 HydrophobicContact CB-CG2 4.08Å; F216-I373 HydrophobicContact CE1-CD1 4.41Å; F216-I373 HydrophobicContact CZ-CD1 4.16Å; I350-I373 HydrophobicContact CG1-CD1 4.37Å; I350-I373 HydrophobicContact CG2-CD1 3.93Å; I350-I373 HydrophobicContact CG2-CG1 3.88Å; I350-I373 HydrophobicContact CG2-CG2 3.91Å; W369-I373 HydrophobicContact CD2-CG1 4.21Å; W369-I373 HydrophobicContact CG-CG1 4.48Å; W369-I373 HydrophobicContact CH2-CD1 4.07Å; W369-I373 HydrophobicContact CZ2-CD1 3.7Å; W369-I373 HydrophobicContact CZ2-CG1 4.09Å; W369-I373 WeakPolarHBondContact O-CG1 3.37Å; W369-I373 PolarHBondContact O-N 2.97Å; I373-A376 WeakPolarHBondContact O-CB 3.46Å; I373-A376 PolarHBondContact O-N 2.88Å; I373-G377 PolarHBondContact O-N 3.33Å
374	L	95.3	Very high	92.2	Very high	36 Å²	36	17.5 Å²	17.5	19%	0.188	10%	0.096	C	C	.	.	H	α-helix	trans	-63.6	-43.7	175.6	-173	63.1	0	0	0	111.1	A165 F166 L169 A370 V371 G372 A376 G377 Q378	A165-L374 HydrophobicContact CB-CB 3.86Å; A165-L374 HydrophobicContact CB-CD1 4.26Å; F166-L374 HydrophobicContact CD1-CD1 4.46Å; F166-L374 HydrophobicContact CE1-CD1 3.92Å; F166-L374 HydrophobicContact CE1-CD2 4.19Å; F166-L374 HydrophobicContact CE2-CD1 4.06Å; F166-L374 HydrophobicContact CZ-CD1 3.7Å; L169-L374 HydrophobicContact CD1-CD2 3.93Å; A370-L374 WeakPolarHBondContact O-CB 3.16Å; A370-L374 PolarHBondContact O-N 3.34Å; V371-L374 PolarHBondContact O-N 3.01Å; G372-L374 PolarHBondContact O-N 3.15Å; L374-A376 VanDerWaalsContact C-N 3.34Å; L374-A376 PolarHBondContact O-N 3.47Å; L374-G377 PolarHBondContact O-N 3.3Å; L374-Q378 HydrophobicContact CD1-CG 4.28Å; L374-Q378 HydrophobicContact CG-CG 4.39Å; L374-Q378 WeakPolarHBondContact O-CB 3.39Å; L374-Q378 WeakPolarHBondContact O-CG 3.49Å; L374-Q378 PolarHBondContact O-N 3.32Å
375	A	95.2	Very high	91.8	Very high	7 Å²	7	15.3 Å²	15.3	6%	0.058	8%	0.077	C	C	.	.	H	α-helix	trans	-61.7	-42.6	176	0	0	0	0	0	111.8	L208 V211 M212 V371 G372 S379	L208-A375 HydrophobicContact CD2-CB 4.17Å; V211-A375 HydrophobicContact CB-CB 4.25Å; V211-A375 HydrophobicContact CG1-CB 3.87Å; M212-A375 HydrophobicContact CG-CB 3.89Å; V371-A375 PolarHBondContact O-N 2.8Å; G372-A375 PolarHBondContact O-N 3.33Å; A375-S379 VanDerWaalsContact O-CB 3.32Å; A375-S379 WeakPolarHBondContact O-CB 3.29Å; A375-S379 PolarHBondContact O-N 3.39Å; A375-S379 PolarHBondContact O-OG 2.94Å; A375-S379 VanDerWaalsContact O-OG 3.13Å
376	A	94.4	Very high	91.4	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-57.3	-55.4	174.1	0	0	0	0	0	111.7	L79 P81 I84 M212 G372 I373 L374 Q378 S379 S380	L79-A376 VanDerWaalsContact O-CB 3.22Å; L79-A376 WeakPolarHBondContact O-CB 3.39Å; P81-A376 HydrophobicContact CG-CB 4.3Å; I84-A376 HydrophobicContact CD1-CB 3.58Å; M212-A376 WeakPolarHBondContact SD-CA 3.32Å; M212-A376 HydrophobicContact SD-CB 3.61Å; G372-A376 PolarHBondContact O-N 3.27Å; I373-A376 WeakPolarHBondContact O-CB 3.46Å; I373-A376 PolarHBondContact O-N 2.88Å; L374-A376 VanDerWaalsContact C-N 3.34Å; L374-A376 PolarHBondContact O-N 3.47Å; A376-Q378 PolarHBondContact O-N 3.47Å; A376-S379 PolarHBondContact O-N 3.45Å; A376-S379 PolarHBondContact O-OG 3.22Å; A376-S380 PolarHBondContact O-N 2.98Å
377	G	92.6	Very high	91.2	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-60.9	-44.6	-178.7	0	0	0	0	0	113	C162 I373 L374 S379 S380 T381	C162-G377 VanDerWaalsContact SG-C 3.55Å; C162-G377 VanDerWaalsContact SG-CA 3.54Å; I373-G377 PolarHBondContact O-N 3.33Å; L374-G377 PolarHBondContact O-N 3.3Å; G377-S379 PolarHBondContact O-N 3.2Å; G377-S380 PolarHBondContact O-N 3.14Å; G377-T381 PolarHBondContact O-N 2.93Å; G377-T381 VanDerWaalsContact O-N 3.1Å; G377-T381 PolarHBondContact O-OG1 3.32Å; G377-T381 VanDerWaalsContact O-OG1 3.12Å
378	Q	90.9	Very high	90.9	Very high	36 Å²	36	10 Å²	10	17%	0.168	6%	0.055	C	C	.	.	H	α-helix	trans	-63.3	-40.6	177.6	-69.7	-62.4	-68.5	0	0	112.7	C162 D186 L374 A376	C162-Q378 PolarHBondContact SG-NE2 2.99Å; C162-Q378 VanDerWaalsContact SG-NE2 3.42Å; D186-Q378 PolarHBondContact OD2-NE2 3.47Å; L374-Q378 HydrophobicContact CD1-CG 4.28Å; L374-Q378 HydrophobicContact CG-CG 4.39Å; L374-Q378 WeakPolarHBondContact O-CB 3.39Å; L374-Q378 WeakPolarHBondContact O-CG 3.49Å; L374-Q378 PolarHBondContact O-N 3.32Å; A376-Q378 PolarHBondContact O-N 3.47Å
379	S	90.4	Very high	90.4	Very high	0 Å²	0	7.9 Å²	7.9	0%	0	4%	0.044	C	C	.	.	H	α-helix	trans	-66.8	-42.3	178.7	67.8	0	0	0	0	111.8	I76 A375 A376 G377 M382 T383	I76-S379 VanDerWaalsContact CG2-OG 3.23Å; I76-S379 WeakPolarHBondContact CG2-OG 3.41Å; A375-S379 VanDerWaalsContact O-CB 3.32Å; A375-S379 WeakPolarHBondContact O-CB 3.29Å; A375-S379 PolarHBondContact O-N 3.39Å; A375-S379 PolarHBondContact O-OG 2.94Å; A375-S379 VanDerWaalsContact O-OG 3.13Å; A376-S379 PolarHBondContact O-N 3.45Å; A376-S379 PolarHBondContact O-OG 3.22Å; G377-S379 PolarHBondContact O-N 3.2Å; S379-M382 PolarHBondContact O-N 2.91Å; S379-T383 PolarHBondContact O-N 3.4Å
380	S	88.1	Confident	90	Very high	0 Å²	0	8 Å²	8	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-67.7	-40.2	-177.9	-172.6	0	0	0	0	112	D80 E158 A376 G377 M382 T383 G384	D80-S380 WeakPolarHBondContact CB-OG 3.35Å; E158-S380 VanDerWaalsContact CD-OG 3.29Å; E158-S380 WeakPolarHBondContact CG-OG 3.37Å; E158-S380 VanDerWaalsContact OE1-CB 3.32Å; E158-S380 WeakPolarHBondContact OE1-CB 3.29Å; E158-S380 PolarHBondContact OE1-OG 3Å; A376-S380 PolarHBondContact O-N 2.98Å; G377-S380 PolarHBondContact O-N 3.14Å; S380-M382 PolarHBondContact O-N 3.44Å; S380-M382 VanDerWaalsContact O-N 3.12Å; S380-T383 WeakPolarHBondContact CA-OG1 3.13Å; S380-T383 CarbonylContact O-C 3.55Å; S380-T383 WeakPolarHBondContact O-CA 3.49Å; S380-T383 WeakPolarHBondContact O-CB 3.15Å; S380-T383 PolarHBondContact O-N 3.39Å; S380-T383 PolarHBondContact O-OG1 3.49Å; S380-G384 PolarHBondContact O-N 3.22Å
381	T	85.3	Confident	89.8	Confident	2 Å²	2	8 Å²	8	1%	0.012	5%	0.045	C	C	.	.	H	α-helix	trans	-50.3	-41.9	175.2	-66.8	0	0	0	0	113.8	E158 D186 G377 T385 R410	E158-T381 VanDerWaalsContact CD-N 3.29Å; E158-T381 PolarHBondContact OE1-N 3.4Å; E158-T381 WeakPolarHBondContact OE2-CA 3.36Å; E158-T381 PolarHBondContact OE2-N 2.95Å; E158-T381 PolarHBondContact OE2-OG1 3.27Å; D186-T381 WeakPolarHBondContact OD1-CG2 3.27Å; G377-T381 PolarHBondContact O-N 2.93Å; G377-T381 VanDerWaalsContact O-N 3.1Å; G377-T381 PolarHBondContact O-OG1 3.32Å; G377-T381 VanDerWaalsContact O-OG1 3.12Å; T381-T385 WeakPolarHBondContact O-CG2 3.47Å; T381-T385 PolarHBondContact O-N 2.9Å; T381-T385 PolarHBondContact O-OG1 3.36Å; T381-R410 PolarHBondContact OG1-NH1 3.27Å
382	M	83.6	Confident	89.4	Confident	2 Å²	2	5.6 Å²	5.6	1%	0.01	3%	0.03	C	C	.	.	H	α-helix	trans	-67.6	-41.7	176.2	-55.4	-173	179.3	0	0	111.2	F190 L193 F204 F205 S379 S380 G384 T385 Y386	F190-M382 HydrophobicContact CB-CE 4.2Å; F190-M382 HydrophobicContact CB-CG 4.15Å; F190-M382 HydrophobicContact CD2-CB 3.67Å; F190-M382 HydrophobicContact CD2-CE 4.37Å; F190-M382 HydrophobicContact CD2-CG 3.41Å; F190-M382 VanDerWaalsContact CD2-CG 3.41Å; F190-M382 HydrophobicContact CD2-SD 3.77Å; F190-M382 HydrophobicContact CE2-CB 3.86Å; F190-M382 HydrophobicContact CE2-CG 4.13Å; F190-M382 HydrophobicContact CG-CB 4.46Å; F190-M382 HydrophobicContact CG-CG 4.02Å; L193-M382 HydrophobicContact CD1-CE 3.86Å; F204-M382 HydrophobicContact CD1-CE 4.36Å; F204-M382 HydrophobicContact CD1-SD 4.21Å; F204-M382 HydrophobicContact CE1-CE 3.56Å; F204-M382 HydrophobicContact CE1-SD 3.88Å; F204-M382 HydrophobicContact CZ-CE 4.31Å; F205-M382 HydrophobicContact CE1-CB 3.73Å; F205-M382 HydrophobicContact CE1-CG 4.22Å; F205-M382 HydrophobicContact CE1-SD 3.78Å; F205-M382 HydrophobicContact CZ-CB 3.45Å; F205-M382 VanDerWaalsContact CZ-CB 3.45Å; F205-M382 HydrophobicContact CZ-CG 4.19Å; F205-M382 HydrophobicContact CZ-SD 3.8Å; S379-M382 PolarHBondContact O-N 2.91Å; S380-M382 PolarHBondContact O-N 3.44Å; S380-M382 VanDerWaalsContact O-N 3.12Å; M382-G384 PolarHBondContact O-N 3.43Å; M382-T385 PolarHBondContact O-N 2.97Å; M382-T385 PolarHBondContact O-OG1 2.91Å; M382-Y386 WeakPolarHBondContact O-CD2 3.31Å; M382-Y386 PolarHBondContact O-N 3.42Å; M382-Y386 VanDerWaalsContact O-N 3.1Å
383	T	85.6	Confident	89	Confident	2 Å²	2	7.1 Å²	7.1	1%	0.012	4%	0.037	C	C	.	.	H	α-helix	trans	-65.8	-36.9	176.9	63.7	0	0	0	0	113.9	I76 L265 S379 S380 Y386 S387	I76-T383 HydrophobicContact CB-CG2 4.01Å; I76-T383 HydrophobicContact CD1-CG2 4.39Å; I76-T383 HydrophobicContact CG2-CG2 3.82Å; L265-T383 HydrophobicContact CD2-CG2 4.32Å; S379-T383 PolarHBondContact O-N 3.4Å; S380-T383 WeakPolarHBondContact CA-OG1 3.13Å; S380-T383 CarbonylContact O-C 3.55Å; S380-T383 WeakPolarHBondContact O-CA 3.49Å; S380-T383 WeakPolarHBondContact O-CB 3.15Å; S380-T383 PolarHBondContact O-N 3.39Å; S380-T383 PolarHBondContact O-OG1 3.49Å; T383-Y386 PolarHBondContact O-N 3.31Å; T383-S387 WeakPolarHBondContact O-CB 3.12Å; T383-S387 PolarHBondContact O-N 3.29Å; T383-S387 PolarHBondContact O-OG 3.45Å
384	G	85.7	Confident	88.6	Confident	2 Å²	2	7.3 Å²	7.3	2%	0.021	4%	0.039	C	C	.	.	H	α-helix	trans	-62.3	-43.4	174.5	0	0	0	0	0	111.9	S380 M382 S387 G388	S380-G384 PolarHBondContact O-N 3.22Å; M382-G384 PolarHBondContact O-N 3.43Å; G384-S387 PolarHBondContact O-N 3.29Å; G384-G388 PolarHBondContact O-N 3.1Å
385	T	83.6	Confident	88.5	Confident	4 Å²	4	5.6 Å²	5.6	3%	0.025	3%	0.03	C	C	.	.	H	α-helix	trans	-65.6	-40.8	176.7	60.7	0	0	0	0	113.2	F190 T381 M382 Q389 V406	F190-T385 WeakPolarHBondContact CE1-OG1 3.5Å; F190-T385 WeakPolarHBondContact CZ-OG1 3.37Å; T381-T385 WeakPolarHBondContact O-CG2 3.47Å; T381-T385 PolarHBondContact O-N 2.9Å; T381-T385 PolarHBondContact O-OG1 3.36Å; M382-T385 PolarHBondContact O-N 2.97Å; M382-T385 PolarHBondContact O-OG1 2.91Å; T385-Q389 WeakPolarHBondContact O-CB 3.22Å; T385-Q389 PolarHBondContact O-N 3.09Å; T385-V406 HydrophobicContact CG2-CG1 3.84Å; T385-V406 HydrophobicContact CG2-CG2 4.11Å
386	Y	84.3	Confident	88	Confident	7 Å²	7	7.4 Å²	7.4	3%	0.027	4%	0.038	C	C	.	.	H	α-helix	trans	-61.5	-45.9	172	-79.4	-65.1	0	0	0	111.7	Y44 F190 D194 L201 M382 T383 Q389 F390	Y44-Y386 HydrophobicContact CD1-CD1 4.39Å; Y44-Y386 AromaticContact CD1-CE1 3.49Å; Y44-Y386 HydrophobicContact CD1-CE1 3.49Å; Y44-Y386 VanDerWaalsContact CD1-CE1 3.49Å; Y44-Y386 AromaticContact CD2-CD1 3.68Å; Y44-Y386 HydrophobicContact CD2-CD1 3.68Å; Y44-Y386 AromaticContact CD2-CE1 3.59Å; Y44-Y386 HydrophobicContact CD2-CE1 3.59Å; Y44-Y386 HydrophobicContact CE1-CD1 4.14Å; Y44-Y386 AromaticContact CE1-CE1 3.34Å; Y44-Y386 HydrophobicContact CE1-CE1 3.34Å; Y44-Y386 AromaticContact CE1-CZ 3.97Å; Y44-Y386 AromaticContact CE2-CD1 3.35Å; Y44-Y386 HydrophobicContact CE2-CD1 3.35Å; Y44-Y386 AromaticContact CE2-CE1 3.41Å; Y44-Y386 HydrophobicContact CE2-CE1 3.41Å; Y44-Y386 VanDerWaalsContact CE2-CE1 3.41Å; Y44-Y386 HydrophobicContact CG-CD1 4.18Å; Y44-Y386 AromaticContact CG-CE1 3.61Å; Y44-Y386 HydrophobicContact CG-CE1 3.61Å; Y44-Y386 AromaticContact CZ-CD1 3.65Å; Y44-Y386 AromaticContact CZ-CE1 3.33Å; F190-Y386 HydrophobicContact CE2-CD2 4.24Å; F190-Y386 AromaticContact CE2-CE2 3.43Å; F190-Y386 HydrophobicContact CE2-CE2 3.43Å; F190-Y386 VanDerWaalsContact CE2-CE2 3.43Å; F190-Y386 AromaticContact CE2-CZ 3.67Å; F190-Y386 HydrophobicContact CZ-CD2 4.18Å; F190-Y386 HydrophobicContact CZ-CE1 4.23Å; F190-Y386 AromaticContact CZ-CE2 3.62Å; F190-Y386 HydrophobicContact CZ-CE2 3.62Å; F190-Y386 AromaticContact CZ-CZ 3.6Å; D194-Y386 PolarHBondContact OD1-OH 3.05Å; L201-Y386 HydrophobicContact CD2-CE2 3.86Å; L201-Y386 WeakPolarHBondContact CD2-OH 3.44Å; M382-Y386 WeakPolarHBondContact O-CD2 3.31Å; M382-Y386 PolarHBondContact O-N 3.42Å; M382-Y386 VanDerWaalsContact O-N 3.1Å; T383-Y386 PolarHBondContact O-N 3.31Å; Y386-Q389 PolarHBondContact O-N 2.9Å; Y386-F390 HydrophobicContact CD1-CE2 4.19Å; Y386-F390 WeakPolarHBondContact O-CD2 3.43Å; Y386-F390 PolarHBondContact O-N 2.81Å
387	S	88.9	Confident	87.6	Confident	0 Å²	0	13 Å²	13	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-61.2	-50.8	-179	-58.3	0	0	0	0	111.4	L265 T383 G384 Q389 F390 V391	L265-S387 WeakPolarHBondContact CB-OG 3.37Å; T383-S387 WeakPolarHBondContact O-CB 3.12Å; T383-S387 PolarHBondContact O-N 3.29Å; T383-S387 PolarHBondContact O-OG 3.45Å; G384-S387 PolarHBondContact O-N 3.29Å; S387-Q389 PolarHBondContact O-N 2.93Å; S387-F390 PolarHBondContact O-N 3.45Å; S387-V391 VanDerWaalsContact O-CB 3.28Å; S387-V391 WeakPolarHBondContact O-CB 3.21Å; S387-V391 WeakPolarHBondContact O-CG2 3.42Å; S387-V391 PolarHBondContact O-N 2.89Å
388	G	87.9	Confident	86.8	Confident	2 Å²	2	17.3 Å²	17.3	2%	0.021	9%	0.09	C	C	.	.	H	α-helix	trans	-59.6	-35.4	176	0	0	0	0	0	112.5	G384 M392	G384-G388 PolarHBondContact O-N 3.1Å; G388-M392 VanDerWaalsContact O-CB 3.3Å; G388-M392 WeakPolarHBondContact O-CB 3.49Å; G388-M392 WeakPolarHBondContact O-CG 3.35Å; G388-M392 PolarHBondContact O-N 3.49Å
389	Q	84.8	Confident	85.9	Confident	1 Å²	1	23.3 Å²	23.3	1%	0.005	12%	0.116	C	C	.	.	H	α-helix	trans	-63.4	-56.4	174.1	169.5	156.8	-11.9	0	0	112.9	T43 Y44 T385 Y386 S387 V391 M392 E393 R405	T43-Q389 VanDerWaalsContact CB-NE2 3.33Å; T43-Q389 PolarHBondContact OG1-NE2 3.4Å; Y44-Q389 HydrophobicContact CE2-CB 4.24Å; Y44-Q389 HydrophobicContact CE2-CG 3.98Å; Y44-Q389 VanDerWaalsContact CZ-OE1 3.25Å; Y44-Q389 PolarHBondContact OH-OE1 2.91Å; T385-Q389 WeakPolarHBondContact O-CB 3.22Å; T385-Q389 PolarHBondContact O-N 3.09Å; Y386-Q389 PolarHBondContact O-N 2.9Å; S387-Q389 PolarHBondContact O-N 2.93Å; Q389-V391 VanDerWaalsContact C-N 3.25Å; Q389-V391 PolarHBondContact O-N 3.34Å; Q389-M392 PolarHBondContact O-N 3.09Å; Q389-E393 PolarHBondContact NE2-OE1 2.95Å; Q389-E393 VanDerWaalsContact NE2-OE1 3.12Å; Q389-E393 PolarHBondContact NE2-OE2 3.24Å; Q389-E393 WeakPolarHBondContact O-CB 3.43Å; Q389-E393 PolarHBondContact O-N 3Å; Q389-R405 VanDerWaalsContact CA-NH1 3.27Å; Q389-R405 PolarHBondContact O-NH1 3.24Å
390	F	88.3	Confident	84.9	Confident	4 Å²	4	28.1 Å²	28.1	2%	0.018	13%	0.134	C	C	.	.	H	α-helix	trans	-63.3	-34.9	-177.7	-66.1	-59	0	0	0	112	Y44 F45 H126 L265 A268 Y386 S387 G394	Y44-F390 HydrophobicContact CD2-CZ 4.28Å; F45-F390 HydrophobicContact CE2-CZ 4.24Å; F45-F390 HydrophobicContact CZ-CZ 4.5Å; H126-F390 PolarHBondContact CE1-O 3.04Å; H126-F390 AromaticContact NE2-CD1 3.92Å; L265-F390 HydrophobicContact CD1-CD2 4.07Å; L265-F390 HydrophobicContact CD1-CE2 4.12Å; A268-F390 HydrophobicContact CB-CB 4.02Å; A268-F390 HydrophobicContact CB-CD1 3.6Å; A268-F390 HydrophobicContact CB-CD2 3.5Å; A268-F390 VanDerWaalsContact CB-CD2 3.5Å; A268-F390 HydrophobicContact CB-CE1 3.85Å; A268-F390 HydrophobicContact CB-CE2 3.76Å; A268-F390 HydrophobicContact CB-CG 3.42Å; A268-F390 VanDerWaalsContact CB-CG 3.42Å; A268-F390 HydrophobicContact CB-CZ 3.93Å; Y386-F390 HydrophobicContact CD1-CE2 4.19Å; Y386-F390 WeakPolarHBondContact O-CD2 3.43Å; Y386-F390 PolarHBondContact O-N 2.81Å; S387-F390 PolarHBondContact O-N 3.45Å; F390-G394 WeakPolarHBondContact O-CA 3.4Å; F390-G394 PolarHBondContact O-N 3.46Å
391	V	91.2	Very high	84.3	Confident	0 Å²	0	31.7 Å²	31.7	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-65.8	-52.5	175.9	167	0	0	0	0	110.4	I147 I151 Y264 S387 Q389 G394 F395	I147-V391 HydrophobicContact CB-CG1 4.16Å; I147-V391 HydrophobicContact CG2-CB 4.35Å; I147-V391 HydrophobicContact CG2-CG1 3.78Å; I147-V391 HydrophobicContact CG2-CG2 3.62Å; I151-V391 HydrophobicContact CD1-CB 4.05Å; I151-V391 HydrophobicContact CD1-CG1 4.19Å; I151-V391 HydrophobicContact CD1-CG2 4Å; Y264-V391 HydrophobicContact CD1-CG2 4.27Å; Y264-V391 HydrophobicContact CG-CG2 4.06Å; S387-V391 VanDerWaalsContact O-CB 3.28Å; S387-V391 WeakPolarHBondContact O-CB 3.21Å; S387-V391 WeakPolarHBondContact O-CG2 3.42Å; S387-V391 PolarHBondContact O-N 2.89Å; Q389-V391 VanDerWaalsContact C-N 3.25Å; Q389-V391 PolarHBondContact O-N 3.34Å; V391-G394 PolarHBondContact O-N 2.83Å; V391-F395 HydrophobicContact CB-CD2 4.46Å; V391-F395 HydrophobicContact CG1-CD2 3.79Å; V391-F395 HydrophobicContact CG1-CE2 4.15Å; V391-F395 WeakPolarHBondContact O-CB 3.26Å; V391-F395 VanDerWaalsContact O-CD2 3.29Å; V391-F395 WeakPolarHBondContact O-CD2 3.26Å; V391-F395 PolarHBondContact O-N 3.09Å
392	M	88.4	Confident	83.7	Confident	13 Å²	13	35.2 Å²	35.2	6%	0.064	17%	0.172	C	C	.	.	H	α-helix	trans	-64.1	-44.8	179.5	-70	-179.5	75.9	0	0	113.1	W144 E148 G388 Q389 L396 W400 R405	W144-M392 HydrophobicContact CZ2-CG 4.5Å; E148-M392 WeakPolarHBondContact OE2-CG 3.38Å; G388-M392 VanDerWaalsContact O-CB 3.3Å; G388-M392 WeakPolarHBondContact O-CB 3.49Å; G388-M392 WeakPolarHBondContact O-CG 3.35Å; G388-M392 PolarHBondContact O-N 3.49Å; Q389-M392 PolarHBondContact O-N 3.09Å; M392-L396 WeakPolarHBondContact O-CB 3.33Å; M392-L396 PolarHBondContact O-N 3.28Å; M392-W400 HydrophobicContact CE-CE3 3.96Å; M392-W400 HydrophobicContact CE-CZ3 4.04Å; M392-R405 HydrophobicContact CE-CG 4.4Å; M392-R405 HydrophobicContact SD-CG 3.64Å
393	E	87.8	Confident	83.4	Confident	32 Å²	32	39.8 Å²	39.8	15%	0.15	19%	0.193	C	C	.	.	H	α-helix	trans	-64.2	-44.9	177.9	-90.6	163.7	-160.7	0	0	111.1	T43 Q389 N397 R405	T43-E393 PolarHBondContact OG1-OE1 3.28Å; Q389-E393 PolarHBondContact NE2-OE1 2.95Å; Q389-E393 VanDerWaalsContact NE2-OE1 3.12Å; Q389-E393 PolarHBondContact NE2-OE2 3.24Å; Q389-E393 WeakPolarHBondContact O-CB 3.43Å; Q389-E393 PolarHBondContact O-N 3Å; E393-N397 WeakPolarHBondContact O-CA 3.44Å; E393-N397 PolarHBondContact O-N 3.23Å; E393-R405 IonicContact OE1-CZ 3.87Å; E393-R405 IonicContact OE1-NH1 2.7Å; E393-R405 PolarHBondContact OE1-NH1 2.91Å; E393-R405 IonicContact OE1-NH2 3.08Å; E393-R405 PolarHBondContact OE1-NH2 2.91Å
394	G	89.3	Confident	83.1	Confident	3 Å²	3	41.1 Å²	41.1	3%	0.031	20%	0.204	C	C	.	.	H	α-helix	trans	-66.9	-51.9	-180	0	0	0	0	0	112.9	A128 N132 F390 V391	A128-G394 CarbonylContact O-C 3.42Å; N132-G394 WeakPolarHBondContact CB-O 3.46Å; F390-G394 WeakPolarHBondContact O-CA 3.4Å; F390-G394 PolarHBondContact O-N 3.46Å; V391-G394 PolarHBondContact O-N 2.83Å
395	F	91.3	Very high	82.8	Confident	0 Å²	0	41.2 Å²	41.2	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-73.8	-39.2	-173.8	-83.3	-77.9	0	0	0	113.7	A128 C131 N132 R140 L143 W144 Y264 V391	A128-F395 HydrophobicContact CB-CD2 3.5Å; A128-F395 HydrophobicContact CB-CE2 3.6Å; A128-F395 HydrophobicContact CB-CG 4.27Å; A128-F395 HydrophobicContact CB-CZ 4.42Å; C131-F395 HydrophobicContact CB-CD1 4.16Å; C131-F395 HydrophobicContact CB-CE1 3.42Å; C131-F395 VanDerWaalsContact CB-CE1 3.42Å; C131-F395 HydrophobicContact CB-CZ 3.8Å; N132-F395 PolarHBondContact ND2-O 3.48Å; R140-F395 WeakPolarHBondContact CD-O 3.41Å; R140-F395 HydrophobicContact CG-CD1 3.91Å; L143-F395 HydrophobicContact CB-CE1 3.95Å; L143-F395 HydrophobicContact CB-CZ 4.35Å; L143-F395 HydrophobicContact CD2-CE1 3.75Å; L143-F395 HydrophobicContact CD2-CZ 3.84Å; L143-F395 HydrophobicContact CG-CE1 3.78Å; L143-F395 HydrophobicContact CG-CZ 3.75Å; W144-F395 HydrophobicContact CB-CB 3.71Å; W144-F395 HydrophobicContact CB-CD1 4.01Å; W144-F395 HydrophobicContact CB-CD2 4.24Å; W144-F395 HydrophobicContact CB-CG 3.74Å; W144-F395 HydrophobicContact CG-CB 3.92Å; W144-F395 HydrophobicContact CG-CG 4.32Å; Y264-F395 HydrophobicContact CD1-CE2 4.14Å; Y264-F395 AromaticContact CE1-CE2 3.55Å; Y264-F395 HydrophobicContact CE1-CE2 3.55Å; Y264-F395 AromaticContact CE1-CZ 3.69Å; Y264-F395 HydrophobicContact CE1-CZ 3.69Å; V391-F395 HydrophobicContact CB-CD2 4.46Å; V391-F395 HydrophobicContact CG1-CD2 3.79Å; V391-F395 HydrophobicContact CG1-CE2 4.15Å; V391-F395 WeakPolarHBondContact O-CB 3.26Å; V391-F395 VanDerWaalsContact O-CD2 3.29Å; V391-F395 WeakPolarHBondContact O-CD2 3.26Å; V391-F395 PolarHBondContact O-N 3.09Å
396	L	86.6	Confident	82.5	Confident	46 Å²	46	41.1 Å²	41.1	24%	0.241	20%	0.203	C	C	.	.	H	α-helix	trans	-107	-9.3	-172.1	-57.3	-179.6	0	0	0	113.7	I141 W144 M392 L398	I141-L396 HydrophobicContact CG1-CD2 4.45Å; W144-L396 HydrophobicContact CD2-CD1 3.74Å; W144-L396 HydrophobicContact CD2-CD2 4.15Å; W144-L396 HydrophobicContact CD2-CG 4.05Å; W144-L396 VanDerWaalsContact CE2-CD1 3.5Å; W144-L396 HydrophobicContact CE3-CD1 4.11Å; W144-L396 HydrophobicContact CE3-CD2 4.3Å; W144-L396 HydrophobicContact CG-CD1 4.34Å; W144-L396 HydrophobicContact CG-CD2 4.29Å; W144-L396 HydrophobicContact CG-CG 4.17Å; W144-L396 HydrophobicContact CH2-CD1 3.99Å; W144-L396 HydrophobicContact CZ2-CD1 3.64Å; W144-L396 HydrophobicContact CZ3-CD1 4.21Å; M392-L396 WeakPolarHBondContact O-CB 3.33Å; M392-L396 PolarHBondContact O-N 3.28Å; L396-L398 HydrophobicContact CB-CB 4.28Å; L396-L398 HydrophobicContact CB-CD1 3.65Å; L396-L398 HydrophobicContact CB-CG 3.73Å; L396-L398 HydrophobicContact CD1-CD1 3.56Å; L396-L398 HydrophobicContact CG-CD1 4.26Å; L396-L398 PolarHBondContact O-N 2.94Å; L396-L398 VanDerWaalsContact O-N 3.15Å
397	N	84	Confident	82.4	Confident	118 Å²	118	43.3 Å²	43.3	63%	0.631	22%	0.215	S	C	*	.			trans	50.8	33.4	-172.6	-159.9	9.4	0	0	0	112.5	E393	E393-N397 WeakPolarHBondContact O-CA 3.44Å; E393-N397 PolarHBondContact O-N 3.23Å
398	L	77.9	Confident	82.1	Confident	89 Å²	89	46.9 Å²	46.9	47%	0.466	23%	0.233	S	C	.	.			trans	-87.3	118.8	-179.2	-77.9	170.9	0	0	0	110.1	L396 W400	L396-L398 HydrophobicContact CB-CB 4.28Å; L396-L398 HydrophobicContact CB-CD1 3.65Å; L396-L398 HydrophobicContact CB-CG 3.73Å; L396-L398 HydrophobicContact CD1-CD1 3.56Å; L396-L398 HydrophobicContact CG-CD1 4.26Å; L396-L398 PolarHBondContact O-N 2.94Å; L396-L398 VanDerWaalsContact O-N 3.15Å; L398-W400 PolarHBondContact O-N 3.39Å
399	K	70.4	Confident	81.7	Confident	163 Å²	163	47.2 Å²	47.2	71%	0.709	24%	0.235	S	C	*	.			trans	-88.1	88.5	173.8	-63	-172.5	-179.2	-173.2	0	109.8
400	W	70.4	Confident	81.6	Confident	100 Å²	100	47.5 Å²	47.5	38%	0.379	24%	0.236	S	C	.	.			trans	-110.7	144.4	178.6	-160	14.3	0	0	0	111.9	M392 L398 R402 A404 R405 L408	M392-W400 HydrophobicContact CE-CE3 3.96Å; M392-W400 HydrophobicContact CE-CZ3 4.04Å; L398-W400 PolarHBondContact O-N 3.39Å; W400-R402 PolarHBondContact O-N 3.09Å; W400-A404 HydrophobicContact CD2-CB 4.35Å; W400-A404 HydrophobicContact CZ2-CB 3.8Å; W400-R405 HydrophobicContact CD2-CB 4.26Å; W400-R405 HydrophobicContact CE3-CB 3.88Å; W400-R405 HydrophobicContact CE3-CG 4.1Å; W400-R405 HydrophobicContact CZ3-CB 4.34Å; W400-R405 HydrophobicContact CZ3-CG 4.44Å; W400-R405 PolarHBondContact O-NH2 2.87Å; W400-L408 HydrophobicContact CH2-CB 3.69Å; W400-L408 HydrophobicContact CH2-CD2 3.49Å; W400-L408 VanDerWaalsContact CH2-CD2 3.49Å; W400-L408 HydrophobicContact CH2-CG 4.04Å; W400-L408 HydrophobicContact CZ3-CB 4.15Å; W400-L408 HydrophobicContact CZ3-CD2 3.58Å; W400-L408 HydrophobicContact CZ3-CG 4.43Å
401	S	76	Confident	81.5	Confident	75 Å²	75	50.3 Å²	50.3	52%	0.524	26%	0.257	S	S	.	.			trans	-54.9	133	173.5	176.2	0	0	0	0	110.9	F403 A404 R405	S401-F403 PolarHBondContact O-N 3.42Å; S401-A404 PolarHBondContact O-N 3.42Å; S401-A404 VanDerWaalsContact O-N 3.15Å; S401-R405 PolarHBondContact O-N 3.22Å; S401-R405 VanDerWaalsContact O-N 3.17Å
402	R	72.4	Confident	81.3	Confident	76 Å²	76	54 Å²	54	29%	0.287	28%	0.275	S	S	.	.	H	α-helix	trans	-47.6	-47.2	177.4	-72.5	-176.6	-84.5	-173.3	-15.4	111.5	T43 D194 W400 R405 V406	T43-R402 HydrophobicContact CG2-CG 3.91Å; D194-R402 IonicContact OD2-CZ 3.32Å; D194-R402 IonicContact OD2-NH1 3.57Å; D194-R402 PolarHBondContact OD2-NH1 2.95Å; W400-R402 PolarHBondContact O-N 3.09Å; R402-R405 PolarHBondContact O-N 2.97Å; R402-V406 WeakPolarHBondContact O-CB 3.45Å; R402-V406 VanDerWaalsContact O-CG2 3.31Å; R402-V406 WeakPolarHBondContact O-CG2 3.4Å; R402-V406 PolarHBondContact O-N 3.3Å; R402-V406 VanDerWaalsContact O-N 3.1Å
403	F	76.3	Confident	81	Confident	99 Å²	99	53.4 Å²	53.4	43%	0.434	27%	0.272	S	S	.	.	H	α-helix	trans	-61.6	-47.6	-178.2	-171.7	-101.1	0	0	0	113.1	F188 L191 S401 R405 L407	F188-F403 HydrophobicContact CD1-CE2 4.3Å; F188-F403 AromaticContact CE1-CE2 3.89Å; F188-F403 HydrophobicContact CE1-CE2 3.89Å; F188-F403 AromaticContact CE1-CZ 3.98Å; F188-F403 HydrophobicContact CE1-CZ 3.98Å; L191-F403 HydrophobicContact CD1-CD2 3.44Å; L191-F403 VanDerWaalsContact CD1-CD2 3.44Å; L191-F403 HydrophobicContact CD1-CE2 3.72Å; S401-F403 PolarHBondContact O-N 3.42Å; F403-R405 VanDerWaalsContact C-N 3.33Å; F403-R405 PolarHBondContact O-N 2.98Å; F403-L407 HydrophobicContact CD1-CD1 3.69Å; F403-L407 HydrophobicContact CD1-CG 4.4Å; F403-L407 HydrophobicContact CE1-CD1 3.14Å; F403-L407 HydrophobicContact CE1-CG 4.12Å; F403-L407 HydrophobicContact CE2-CD1 4.32Å; F403-L407 HydrophobicContact CG-CD1 4.48Å; F403-L407 HydrophobicContact CZ-CD1 3.51Å; F403-L407 HydrophobicContact CZ-CG 4.2Å; F403-L407 WeakPolarHBondContact O-CB 3.17Å; F403-L407 WeakPolarHBondContact O-CG 3.15Å; F403-L407 PolarHBondContact O-N 3.31Å
404	A	80.5	Confident	81	Confident	30 Å²	30	52.5 Å²	52.5	25%	0.248	27%	0.268	C	S	.	.	H	α-helix	trans	-68	-36.3	-175.7	0	0	0	0	0	111.9	W400 S401 L408	W400-A404 HydrophobicContact CD2-CB 4.35Å; W400-A404 HydrophobicContact CZ2-CB 3.8Å; S401-A404 PolarHBondContact O-N 3.42Å; S401-A404 VanDerWaalsContact O-N 3.15Å; A404-L408 WeakPolarHBondContact O-CB 3.25Å; A404-L408 PolarHBondContact O-N 2.8Å
405	R	77.5	Confident	81	Confident	4 Å²	4	56 Å²	56	2%	0.015	29%	0.289	C	S	.	.	H	α-helix	trans	-67.3	-52.5	177.3	-172	-175.6	-45.2	-166.9	16	112	Q389 M392 E393 W400 S401 R402 F403 L407 L408 T409	Q389-R405 VanDerWaalsContact CA-NH1 3.27Å; Q389-R405 PolarHBondContact O-NH1 3.24Å; M392-R405 HydrophobicContact CE-CG 4.4Å; M392-R405 HydrophobicContact SD-CG 3.64Å; E393-R405 IonicContact OE1-CZ 3.87Å; E393-R405 IonicContact OE1-NH1 2.7Å; E393-R405 PolarHBondContact OE1-NH1 2.91Å; E393-R405 IonicContact OE1-NH2 3.08Å; E393-R405 PolarHBondContact OE1-NH2 2.91Å; W400-R405 HydrophobicContact CD2-CB 4.26Å; W400-R405 HydrophobicContact CE3-CB 3.88Å; W400-R405 HydrophobicContact CE3-CG 4.1Å; W400-R405 HydrophobicContact CZ3-CB 4.34Å; W400-R405 HydrophobicContact CZ3-CG 4.44Å; W400-R405 PolarHBondContact O-NH2 2.87Å; S401-R405 PolarHBondContact O-N 3.22Å; S401-R405 VanDerWaalsContact O-N 3.17Å; R402-R405 PolarHBondContact O-N 2.97Å; F403-R405 VanDerWaalsContact C-N 3.33Å; F403-R405 PolarHBondContact O-N 2.98Å; R405-L407 VanDerWaalsContact C-N 3.28Å; R405-L407 PolarHBondContact O-N 3.01Å; R405-L408 WeakPolarHBondContact O-CB 3.15Å; R405-L408 PolarHBondContact O-N 3.47Å; R405-T409 PolarHBondContact O-N 3.29Å; R405-T409 PolarHBondContact O-OG1 3.37Å
406	V	78.3	Confident	80.7	Confident	2 Å²	2	58 Å²	58	1%	0.012	30%	0.303	C	S	.	.	H	α-helix	trans	-59.7	-42.2	-179.4	170.9	0	0	0	0	110.4	T187 T385 R402 L408 T409 R410	T187-V406 HydrophobicContact CG2-CG1 3.25Å; T385-V406 HydrophobicContact CG2-CG1 3.84Å; T385-V406 HydrophobicContact CG2-CG2 4.11Å; R402-V406 WeakPolarHBondContact O-CB 3.45Å; R402-V406 VanDerWaalsContact O-CG2 3.31Å; R402-V406 WeakPolarHBondContact O-CG2 3.4Å; R402-V406 PolarHBondContact O-N 3.3Å; R402-V406 VanDerWaalsContact O-N 3.1Å; V406-L408 PolarHBondContact O-N 3.48Å; V406-T409 PolarHBondContact O-OG1 3.48Å; V406-R410 HydrophobicContact CG1-CG 4.37Å; V406-R410 VanDerWaalsContact O-CB 3.24Å; V406-R410 WeakPolarHBondContact O-CB 3.05Å; V406-R410 VanDerWaalsContact O-CG 3.23Å; V406-R410 WeakPolarHBondContact O-CG 3.43Å; V406-R410 PolarHBondContact O-N 2.93Å
407	L	81.6	Confident	80.5	Confident	52 Å²	52	55.9 Å²	55.9	27%	0.272	29%	0.291	S	S	.	.	H	α-helix	trans	-63	-40.2	173.7	-78.3	-176.9	0	0	0	112.8	F403 R405 S411	F403-L407 HydrophobicContact CD1-CD1 3.69Å; F403-L407 HydrophobicContact CD1-CG 4.4Å; F403-L407 HydrophobicContact CE1-CD1 3.14Å; F403-L407 HydrophobicContact CE1-CG 4.12Å; F403-L407 HydrophobicContact CE2-CD1 4.32Å; F403-L407 HydrophobicContact CG-CD1 4.48Å; F403-L407 HydrophobicContact CZ-CD1 3.51Å; F403-L407 HydrophobicContact CZ-CG 4.2Å; F403-L407 WeakPolarHBondContact O-CB 3.17Å; F403-L407 WeakPolarHBondContact O-CG 3.15Å; F403-L407 PolarHBondContact O-N 3.31Å; R405-L407 VanDerWaalsContact C-N 3.28Å; R405-L407 PolarHBondContact O-N 3.01Å; L407-S411 WeakPolarHBondContact O-CB 3.38Å; L407-S411 PolarHBondContact O-N 3.12Å; L407-S411 PolarHBondContact O-OG 2.92Å
408	L	83.8	Confident	80.7	Confident	75 Å²	75	52 Å²	52	39%	0.393	27%	0.271	S	S	.	.	H	α-helix	trans	-63.2	-54.9	178	-178.4	77.3	0	0	0	110.8	W400 A404 R405 V406 R410 S411 I412	W400-L408 HydrophobicContact CH2-CB 3.69Å; W400-L408 HydrophobicContact CH2-CD2 3.49Å; W400-L408 VanDerWaalsContact CH2-CD2 3.49Å; W400-L408 HydrophobicContact CH2-CG 4.04Å; W400-L408 HydrophobicContact CZ3-CB 4.15Å; W400-L408 HydrophobicContact CZ3-CD2 3.58Å; W400-L408 HydrophobicContact CZ3-CG 4.43Å; A404-L408 WeakPolarHBondContact O-CB 3.25Å; A404-L408 PolarHBondContact O-N 2.8Å; R405-L408 WeakPolarHBondContact O-CB 3.15Å; R405-L408 PolarHBondContact O-N 3.47Å; V406-L408 PolarHBondContact O-N 3.48Å; L408-R410 VanDerWaalsContact C-N 3.32Å; L408-R410 PolarHBondContact O-N 3.06Å; L408-S411 PolarHBondContact O-N 2.94Å; L408-S411 VanDerWaalsContact O-N 3.13Å; L408-I412 HydrophobicContact CD1-CD1 4.15Å; L408-I412 HydrophobicContact CD2-CD1 4.18Å; L408-I412 HydrophobicContact CG-CD1 3.84Å; L408-I412 WeakPolarHBondContact O-CG1 3.19Å; L408-I412 PolarHBondContact O-N 2.95Å
409	T	78.1	Confident	81	Confident	10 Å²	10	52.1 Å²	52.1	6%	0.061	27%	0.271	C	S	.	.	H	α-helix	trans	-61.8	-43	-175.8	55.1	0	0	0	0	110.9	R405 V406 S411 I412 A413	R405-T409 PolarHBondContact O-N 3.29Å; R405-T409 PolarHBondContact O-OG1 3.37Å; V406-T409 PolarHBondContact O-OG1 3.48Å; T409-S411 PolarHBondContact O-N 3.09Å; T409-I412 PolarHBondContact O-N 2.79Å; T409-A413 PolarHBondContact O-N 3.44Å
410	R	83.7	Confident	81.5	Confident	6 Å²	6	46 Å²	46	2%	0.023	25%	0.247	C	C	.	.	H	α-helix	trans	-64.3	-39.3	174.5	-71.3	-72.1	123	161.6	7	112.3	D155 E158 T187 T381 V406 L408 I412 A413 I414	D155-R410 IonicContact OD1-CZ 3.02Å; D155-R410 IonicContact OD1-NE 3.43Å; D155-R410 PolarHBondContact OD1-NE 3.49Å; D155-R410 VanDerWaalsContact OD1-NE 3.08Å; D155-R410 IonicContact OD1-NH1 3.58Å; D155-R410 PolarHBondContact OD1-NH1 2.82Å; D155-R410 IonicContact OD1-NH2 2.86Å; D155-R410 PolarHBondContact OD1-NH2 3.3Å; D155-R410 VanDerWaalsContact OD1-NH2 3.07Å; D155-R410 IonicContact OD2-CZ 3.27Å; D155-R410 IonicContact OD2-NE 3.98Å; D155-R410 PolarHBondContact OD2-NE 2.76Å; D155-R410 IonicContact OD2-NH1 3.8Å; D155-R410 IonicContact OD2-NH2 2.83Å; D155-R410 PolarHBondContact OD2-NH2 2.93Å; E158-R410 IonicContact OE2-CZ 2.6Å; E158-R410 IonicContact OE2-NH1 2.98Å; E158-R410 PolarHBondContact OE2-NH1 3.15Å; E158-R410 IonicContact OE2-NH2 2.71Å; E158-R410 PolarHBondContact OE2-NH2 3.38Å; T187-R410 HydrophobicContact CG2-CG 4.18Å; T381-R410 PolarHBondContact OG1-NH1 3.27Å; V406-R410 HydrophobicContact CG1-CG 4.37Å; V406-R410 VanDerWaalsContact O-CB 3.24Å; V406-R410 WeakPolarHBondContact O-CB 3.05Å; V406-R410 VanDerWaalsContact O-CG 3.23Å; V406-R410 WeakPolarHBondContact O-CG 3.43Å; V406-R410 PolarHBondContact O-N 2.93Å; L408-R410 VanDerWaalsContact C-N 3.32Å; L408-R410 PolarHBondContact O-N 3.06Å; R410-I412 VanDerWaalsContact C-N 3.33Å; R410-I412 PolarHBondContact O-N 3.4Å; R410-A413 PolarHBondContact O-N 3.17Å; R410-I414 HydrophobicContact CB-CD1 4.26Å; R410-I414 WeakPolarHBondContact O-CB 3.24Å; R410-I414 WeakPolarHBondContact O-CG1 3.41Å; R410-I414 PolarHBondContact O-N 3.27Å
411	S	86.6	Confident	82	Confident	64 Å²	64	41.8 Å²	41.8	45%	0.448	23%	0.234	S	C	.	.	H	α-helix	trans	-63.3	-41.4	176.2	-61.7	0	0	0	0	111.5	L407 L408 T409 T415	L407-S411 WeakPolarHBondContact O-CB 3.38Å; L407-S411 PolarHBondContact O-N 3.12Å; L407-S411 PolarHBondContact O-OG 2.92Å; L408-S411 PolarHBondContact O-N 2.94Å; L408-S411 VanDerWaalsContact O-N 3.13Å; T409-S411 PolarHBondContact O-N 3.09Å; S411-T415 VanDerWaalsContact O-CB 3.32Å; S411-T415 WeakPolarHBondContact O-CB 3.49Å; S411-T415 PolarHBondContact O-N 3.17Å; S411-T415 PolarHBondContact O-OG1 3.42Å
412	I	86.3	Confident	82.3	Confident	77 Å²	77	42.6 Å²	42.6	40%	0.395	23%	0.231	S	C	.	.	H	α-helix	trans	-66.2	-38.2	178.2	-66.5	169.4	0	0	0	111.1	I152 L408 T409 R410 P416	I152-I412 HydrophobicContact CD1-CG2 3.84Å; I152-I412 HydrophobicContact CG1-CG2 4.34Å; I152-I412 HydrophobicContact CG2-CG2 4.19Å; L408-I412 HydrophobicContact CD1-CD1 4.15Å; L408-I412 HydrophobicContact CD2-CD1 4.18Å; L408-I412 HydrophobicContact CG-CD1 3.84Å; L408-I412 WeakPolarHBondContact O-CG1 3.19Å; L408-I412 PolarHBondContact O-N 2.95Å; T409-I412 PolarHBondContact O-N 2.79Å; R410-I412 VanDerWaalsContact C-N 3.33Å; R410-I412 PolarHBondContact O-N 3.4Å; I412-P416 WeakPolarHBondContact O-CD 3.22Å; I412-P416 WeakPolarHBondContact O-CG 3.33Å
413	A	82.7	Confident	82.5	Confident	0 Å²	0	46 Å²	46	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-77.6	-39	178.3	0	0	0	0	0	113.4	I152 D155 M156 T409 R410 P416 T417	I152-A413 HydrophobicContact CG2-CB 4.34Å; D155-A413 HydrophobicContact CB-CB 3.75Å; D155-A413 VanDerWaalsContact OD1-CB 3.29Å; D155-A413 WeakPolarHBondContact OD1-CB 3.49Å; D155-A413 WeakPolarHBondContact OD2-CB 3.3Å; M156-A413 HydrophobicContact CG-CB 4.16Å; T409-A413 PolarHBondContact O-N 3.44Å; R410-A413 PolarHBondContact O-N 3.17Å; A413-P416 WeakPolarHBondContact O-CD 3.38Å; A413-P416 WeakPolarHBondContact O-CG 3.48Å; A413-T417 PolarHBondContact O-OG1 3.25Å; A413-T417 VanDerWaalsContact O-OG1 3.11Å
414	I	87.6	Confident	82.1	Confident	13 Å²	13	45.9 Å²	45.9	7%	0.067	25%	0.249	C	C	.	.	H	α-helix	trans	-72.8	-36.7	-178.1	-69.8	170.9	0	0	0	111.3	V159 V180 I184 R410 T417 L418	V159-I414 HydrophobicContact CG1-CG1 4.38Å; V159-I414 HydrophobicContact CG2-CG1 4.03Å; V180-I414 HydrophobicContact CG1-CG2 3.8Å; I184-I414 HydrophobicContact CG1-CD1 3.64Å; R410-I414 HydrophobicContact CB-CD1 4.26Å; R410-I414 WeakPolarHBondContact O-CB 3.24Å; R410-I414 WeakPolarHBondContact O-CG1 3.41Å; R410-I414 PolarHBondContact O-N 3.27Å; I414-T417 PolarHBondContact O-N 2.86Å; I414-L418 HydrophobicContact CG2-CB 4.42Å; I414-L418 WeakPolarHBondContact O-CB 3.43Å; I414-L418 PolarHBondContact O-N 3.18Å
415	T	89.1	Confident	81.3	Confident	76 Å²	76	50.3 Å²	50.3	47%	0.466	27%	0.269	S	S	.	.	H	α-helix	trans	-54.7	-55.5	-177.7	-61.5	0	0	0	0	113.7	S411 T417 L418 L419	S411-T415 VanDerWaalsContact O-CB 3.32Å; S411-T415 WeakPolarHBondContact O-CB 3.49Å; S411-T415 PolarHBondContact O-N 3.17Å; S411-T415 PolarHBondContact O-OG1 3.42Å; T415-T417 VanDerWaalsContact C-N 3.33Å; T415-T417 PolarHBondContact O-N 2.89Å; T415-L418 PolarHBondContact O-N 3.29Å; T415-L419 HydrophobicContact CG2-CD1 4.17Å; T415-L419 VanDerWaalsContact O-CG 3.29Å; T415-L419 WeakPolarHBondContact O-CG 3.45Å; T415-L419 PolarHBondContact O-N 3.45Å
416	P	83.8	Confident	80.4	Confident	44 Å²	44	52.1 Å²	52.1	29%	0.286	28%	0.28	S	S	.	.	H	α-helix	trans	-62.8	-40.8	178.7	24.7	-33.2	0	0	0	111.6	M156 I412 A413 L418 L419 V420	M156-P416 HydrophobicContact CE-CB 4.04Å; M156-P416 HydrophobicContact CE-CG 3.85Å; M156-P416 HydrophobicContact CG-CG 4.49Å; M156-P416 HydrophobicContact SD-CG 3.89Å; I412-P416 WeakPolarHBondContact O-CD 3.22Å; I412-P416 WeakPolarHBondContact O-CG 3.33Å; A413-P416 WeakPolarHBondContact O-CD 3.38Å; A413-P416 WeakPolarHBondContact O-CG 3.48Å; P416-L418 PolarHBondContact O-N 3.47Å; P416-L419 PolarHBondContact O-N 3.06Å; P416-V420 WeakPolarHBondContact O-CG2 3.28Å; P416-V420 PolarHBondContact O-N 3Å
417	T	83.8	Confident	79.5	Confident	0 Å²	0	56.3 Å²	56.3	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-64.2	-41.1	179.2	-53.1	0	0	0	0	112.2	V159 I160 V180 A413 I414 T415 V420 A421 L429 M432	V159-T417 HydrophobicContact CG1-CG2 3.91Å; I160-T417 HydrophobicContact CG1-CG2 3.77Å; V180-T417 HydrophobicContact CG1-CG2 4.46Å; V180-T417 HydrophobicContact CG2-CG2 3.98Å; A413-T417 PolarHBondContact O-OG1 3.25Å; A413-T417 VanDerWaalsContact O-OG1 3.11Å; I414-T417 PolarHBondContact O-N 2.86Å; T415-T417 VanDerWaalsContact C-N 3.33Å; T415-T417 PolarHBondContact O-N 2.89Å; T417-V420 PolarHBondContact O-N 3.1Å; T417-A421 VanDerWaalsContact O-CB 3.27Å; T417-A421 WeakPolarHBondContact O-CB 3.25Å; T417-A421 PolarHBondContact O-N 2.86Å; T417-L429 HydrophobicContact CG2-CD2 4.43Å; T417-M432 HydrophobicContact CG2-CE 4.14Å
418	L	87.6	Confident	78.7	Confident	38 Å²	38	58.6 Å²	58.6	20%	0.199	31%	0.311	C	S	.	.	H	α-helix	trans	-67	-42	176.7	-177.1	65	0	0	0	111.4	W177 V180 L181 I414 T415 P416 A421 I422	W177-L418 HydrophobicContact CB-CD1 4.12Å; V180-L418 HydrophobicContact CB-CD1 4.44Å; V180-L418 HydrophobicContact CG1-CB 4.06Å; V180-L418 HydrophobicContact CG1-CD1 4.17Å; L181-L418 HydrophobicContact CD2-CD1 4.19Å; L181-L418 HydrophobicContact CD2-CD2 3.97Å; L181-L418 HydrophobicContact CG-CD1 4.15Å; I414-L418 HydrophobicContact CG2-CB 4.42Å; I414-L418 WeakPolarHBondContact O-CB 3.43Å; I414-L418 PolarHBondContact O-N 3.18Å; T415-L418 PolarHBondContact O-N 3.29Å; P416-L418 PolarHBondContact O-N 3.47Å; L418-A421 PolarHBondContact O-N 3.38Å; L418-I422 HydrophobicContact CD1-CD1 3.94Å; L418-I422 HydrophobicContact CD1-CG1 4.26Å; L418-I422 HydrophobicContact CD2-CD1 4.47Å; L418-I422 HydrophobicContact CG-CD1 3.81Å; L418-I422 HydrophobicContact CG-CG1 4.47Å; L418-I422 WeakPolarHBondContact O-CB 3.46Å; L418-I422 VanDerWaalsContact O-CG1 3.27Å; L418-I422 WeakPolarHBondContact O-CG1 3.43Å; L418-I422 PolarHBondContact O-N 3.29Å
419	L	85.2	Confident	77.7	Confident	90 Å²	90	55.3 Å²	55.3	47%	0.471	30%	0.295	S	S	.	.	H	α-helix	trans	-60.4	-47.3	175.5	-72.2	173.3	0	0	0	111	T415 P416 A421 I422 F423	T415-L419 HydrophobicContact CG2-CD1 4.17Å; T415-L419 VanDerWaalsContact O-CG 3.29Å; T415-L419 WeakPolarHBondContact O-CG 3.45Å; T415-L419 PolarHBondContact O-N 3.45Å; P416-L419 PolarHBondContact O-N 3.06Å; L419-A421 VanDerWaalsContact C-N 3.34Å; L419-A421 PolarHBondContact O-N 3.4Å; L419-I422 PolarHBondContact O-N 2.98Å; L419-F423 HydrophobicContact CD2-CD2 4.19Å; L419-F423 HydrophobicContact CD2-CE2 3.8Å; L419-F423 WeakPolarHBondContact O-CB 3.38Å; L419-F423 VanDerWaalsContact O-CD2 3.25Å; L419-F423 WeakPolarHBondContact O-CD2 3.45Å; L419-F423 PolarHBondContact O-N 3.16Å
420	V	80.5	Confident	77	Confident	35 Å²	35	55.4 Å²	55.4	21%	0.212	30%	0.295	C	S	.	.	H	α-helix	trans	-62.1	-43.3	176	178.7	0	0	0	0	110.3	P416 T417 I422 F423 Q424 H428 L429 M432	P416-V420 WeakPolarHBondContact O-CG2 3.28Å; P416-V420 PolarHBondContact O-N 3Å; T417-V420 PolarHBondContact O-N 3.1Å; V420-I422 VanDerWaalsContact C-N 3.3Å; V420-I422 PolarHBondContact O-N 2.93Å; V420-F423 PolarHBondContact O-N 2.87Å; V420-Q424 HydrophobicContact CG1-CB 4.08Å; V420-Q424 HydrophobicContact CG1-CG 4.38Å; V420-Q424 WeakPolarHBondContact O-CA 3.3Å; V420-Q424 VanDerWaalsContact O-CB 3.3Å; V420-Q424 WeakPolarHBondContact O-CB 3.4Å; V420-Q424 PolarHBondContact O-N 3.13Å; V420-H428 HydrophobicContact CG1-CB 4.38Å; V420-L429 HydrophobicContact CB-CD2 3.88Å; V420-L429 HydrophobicContact CG1-CD2 3.51Å; V420-L429 HydrophobicContact CG1-CG 3.9Å; V420-M432 HydrophobicContact CG2-SD 4.21Å
421	A	81.1	Confident	76.3	Confident	12 Å²	12	57 Å²	57	10%	0.099	31%	0.313	C	S	.	.	H	α-helix	trans	-67.4	-24.2	-179.8	0	0	0	0	0	114.9	W177 V180 T417 L418 L419 L429	W177-A421 HydrophobicContact CB-CB 4.1Å; V180-A421 HydrophobicContact CG2-CB 4.42Å; T417-A421 VanDerWaalsContact O-CB 3.27Å; T417-A421 WeakPolarHBondContact O-CB 3.25Å; T417-A421 PolarHBondContact O-N 2.86Å; L418-A421 PolarHBondContact O-N 3.38Å; L419-A421 VanDerWaalsContact C-N 3.34Å; L419-A421 PolarHBondContact O-N 3.4Å; A421-L429 HydrophobicContact CB-CD1 4.07Å; A421-L429 HydrophobicContact CB-CD2 4.34Å
422	I	82.6	Confident	75.7	Confident	92 Å²	92	55.3 Å²	55.3	47%	0.472	30%	0.298	S	S	.	.	H	α-helix	trans	-86.6	-42.7	176.5	-69.5	169.9	0	0	0	111.1	W177 L418 L419 V420	W177-I422 HydrophobicContact CB-CG1 3.92Å; W177-I422 HydrophobicContact CG-CG1 4.47Å; L418-I422 HydrophobicContact CD1-CD1 3.94Å; L418-I422 HydrophobicContact CD1-CG1 4.26Å; L418-I422 HydrophobicContact CD2-CD1 4.47Å; L418-I422 HydrophobicContact CG-CD1 3.81Å; L418-I422 HydrophobicContact CG-CG1 4.47Å; L418-I422 WeakPolarHBondContact O-CB 3.46Å; L418-I422 VanDerWaalsContact O-CG1 3.27Å; L418-I422 WeakPolarHBondContact O-CG1 3.43Å; L418-I422 PolarHBondContact O-N 3.29Å; L419-I422 PolarHBondContact O-N 2.98Å; V420-I422 VanDerWaalsContact C-N 3.3Å; V420-I422 PolarHBondContact O-N 2.93Å
423	F	76.8	Confident	75.3	Confident	148 Å²	148	51.7 Å²	51.7	65%	0.649	28%	0.28	S	S	*	.	H	α-helix	trans	-99.6	-10.8	-169.1	-68.2	-70.6	0	0	0	114.4	L419 V420	L419-F423 HydrophobicContact CD2-CD2 4.19Å; L419-F423 HydrophobicContact CD2-CE2 3.8Å; L419-F423 WeakPolarHBondContact O-CB 3.38Å; L419-F423 VanDerWaalsContact O-CD2 3.25Å; L419-F423 WeakPolarHBondContact O-CD2 3.45Å; L419-F423 PolarHBondContact O-N 3.16Å; V420-F423 PolarHBondContact O-N 2.87Å
424	Q	66.7	Low	74.9	Confident	96 Å²	96	54.2 Å²	54.2	45%	0.449	29%	0.293	S	S	.	.	S	Bend	trans	-134	154.9	-176.1	-57.7	-71.3	-70.8	0	0	111.9	V420 H428	V420-Q424 HydrophobicContact CG1-CB 4.08Å; V420-Q424 HydrophobicContact CG1-CG 4.38Å; V420-Q424 WeakPolarHBondContact O-CA 3.3Å; V420-Q424 VanDerWaalsContact O-CB 3.3Å; V420-Q424 WeakPolarHBondContact O-CB 3.4Å; V420-Q424 PolarHBondContact O-N 3.13Å; Q424-H428 HydrophobicContact CB-CB 3.87Å; Q424-H428 HydrophobicContact CG-CB 4.48Å
425	D	63.9	Low	74.4	Confident	122 Å²	122	58.9 Å²	58.9	65%	0.652	31%	0.313	S	S	*	.			trans	-73.9	164.5	177.6	-64.2	-45.9	0	0	0	113	N427 H428	D425-N427 PolarHBondContact O-N 2.88Å; D425-H428 PolarHBondContact O-N 3.39Å
426	V	59	Low	74.2	Confident	42 Å²	42	55.6 Å²	55.6	26%	0.255	29%	0.293	S	S	.	.	H	α-helix	trans	-46.9	-38.9	-179.3	-172.6	0	0	0	0	113.3	L176 Y351 H428 L429 T430	L176-V426 HydrophobicContact CD1-CB 4.2Å; L176-V426 HydrophobicContact CD1-CG1 4.05Å; L176-V426 HydrophobicContact CD1-CG2 3.69Å; Y351-V426 HydrophobicContact CD1-CG1 4.08Å; Y351-V426 HydrophobicContact CG-CG1 4.35Å; V426-H428 PolarHBondContact O-N 3.46Å; V426-L429 PolarHBondContact O-N 3.25Å; V426-L429 VanDerWaalsContact O-N 3.13Å; V426-T430 PolarHBondContact O-N 3.03Å; V426-T430 PolarHBondContact O-OG1 2.89Å
427	N	59.6	Low	74.1	Confident	91 Å²	91	53.9 Å²	53.9	49%	0.487	28%	0.281	S	S	.	.	H	α-helix	trans	-61.9	-24.8	-179.1	-65.4	-37	0	0	0	113.7	D425 T430 G431	D425-N427 PolarHBondContact O-N 2.88Å; N427-T430 PolarHBondContact O-OG1 3.3Å; N427-T430 VanDerWaalsContact O-OG1 3.14Å; N427-G431 PolarHBondContact O-N 2.92Å
428	H	63.3	Low	73.8	Confident	99 Å²	99	54.8 Å²	54.8	46%	0.458	29%	0.287	S	S	.	.	H	α-helix	trans	-84.9	-26.6	178.1	-65.4	90.5	0	0	0	112.3	V420 Q424 D425 V426 T430 M432	V420-H428 HydrophobicContact CG1-CB 4.38Å; Q424-H428 HydrophobicContact CB-CB 3.87Å; Q424-H428 HydrophobicContact CG-CB 4.48Å; D425-H428 PolarHBondContact O-N 3.39Å; V426-H428 PolarHBondContact O-N 3.46Å; H428-T430 VanDerWaalsContact C-N 3.34Å; H428-M432 WeakPolarHBondContact O-CB 3.25Å; H428-M432 PolarHBondContact O-N 3.4Å; H428-M432 VanDerWaalsContact O-N 3.17Å
429	L	64.6	Low	73.7	Confident	7 Å²	7	54.4 Å²	54.4	4%	0.037	29%	0.285	C	S	.	.	H	α-helix	trans	-70.7	-33	173.5	-72.9	167.6	0	0	0	111.5	L176 T417 V420 A421 V426 M432	L176-L429 HydrophobicContact CB-CD1 4.24Å; L176-L429 HydrophobicContact CD1-CD1 3.53Å; L176-L429 HydrophobicContact CG-CD1 4.47Å; T417-L429 HydrophobicContact CG2-CD2 4.43Å; V420-L429 HydrophobicContact CB-CD2 3.88Å; V420-L429 HydrophobicContact CG1-CD2 3.51Å; V420-L429 HydrophobicContact CG1-CG 3.9Å; A421-L429 HydrophobicContact CB-CD1 4.07Å; A421-L429 HydrophobicContact CB-CD2 4.34Å; V426-L429 PolarHBondContact O-N 3.25Å; V426-L429 VanDerWaalsContact O-N 3.13Å; L429-M432 HydrophobicContact CD2-CE 4.03Å; L429-M432 WeakPolarHBondContact O-CB 3.39Å
430	T	62.3	Low	73.7	Confident	12 Å²	12	50.1 Å²	50.1	7%	0.074	26%	0.262	C	S	.	.	H	α-helix	trans	-78.7	-43.2	179.6	53.5	0	0	0	0	111.4	D349 V426 N427 H428 M432 N433 D434	D349-T430 HydrophobicContact CB-CG2 3.51Å; D349-T430 WeakPolarHBondContact OD2-CG2 3.26Å; D349-T430 PolarHBondContact OD2-OG1 2.87Å; V426-T430 PolarHBondContact O-N 3.03Å; V426-T430 PolarHBondContact O-OG1 2.89Å; N427-T430 PolarHBondContact O-OG1 3.3Å; N427-T430 VanDerWaalsContact O-OG1 3.14Å; H428-T430 VanDerWaalsContact C-N 3.34Å; T430-M432 PolarHBondContact O-N 3.46Å; T430-M432 VanDerWaalsContact O-N 3.17Å; T430-N433 WeakPolarHBondContact O-CB 3.41Å; T430-N433 PolarHBondContact O-N 3.49Å; T430-D434 PolarHBondContact O-N 2.97Å
431	G	69.1	Low	73.9	Confident	38 Å²	38	48.7 Å²	48.7	39%	0.392	25%	0.254	S	S	.	.	H	α-helix	trans	-59.5	-25.7	169.5	0	0	0	0	0	113.9	N427 F435	N427-G431 PolarHBondContact O-N 2.92Å; G431-F435 PolarHBondContact O-N 2.86Å
432	M	74.5	Confident	74.1	Confident	29 Å²	29	50.2 Å²	50.2	14%	0.143	26%	0.26	C	S	.	.	H	α-helix	trans	-67.1	-35.4	171.9	-173.4	167.3	75.4	0	0	112	M156 I160 T417 V420 H428 L429 T430 F435 L436	M156-M432 HydrophobicContact CE-CE 3.86Å; M156-M432 HydrophobicContact CE-CG 4.36Å; M156-M432 HydrophobicContact CE-SD 3.56Å; M156-M432 VanDerWaalsContact CE-SD 3.56Å; I160-M432 HydrophobicContact CD1-CE 3.27Å; I160-M432 HydrophobicContact CD1-CG 4.5Å; I160-M432 HydrophobicContact CG1-CE 3.77Å; T417-M432 HydrophobicContact CG2-CE 4.14Å; V420-M432 HydrophobicContact CG2-SD 4.21Å; H428-M432 WeakPolarHBondContact O-CB 3.25Å; H428-M432 PolarHBondContact O-N 3.4Å; H428-M432 VanDerWaalsContact O-N 3.17Å; L429-M432 HydrophobicContact CD2-CE 4.03Å; L429-M432 WeakPolarHBondContact O-CB 3.39Å; T430-M432 PolarHBondContact O-N 3.46Å; T430-M432 VanDerWaalsContact O-N 3.17Å; M432-F435 PolarHBondContact O-N 3.46Å; M432-L436 HydrophobicContact CG-CD1 4.06Å; M432-L436 HydrophobicContact CG-CG 4.39Å; M432-L436 WeakPolarHBondContact O-CB 3.29Å; M432-L436 WeakPolarHBondContact O-CG 3.39Å; M432-L436 PolarHBondContact O-N 2.97Å
433	N	76.9	Confident	74.5	Confident	2 Å²	2	46.3 Å²	46.3	1%	0.011	24%	0.24	C	C	.	.	H	α-helix	trans	-65.5	-41.6	179	-160.9	16.9	0	0	0	111.7	E85 Q157 T430 F435 L436 N437	E85-N433 WeakPolarHBondContact CB-ND2 3.37Å; E85-N433 HydrophobicContact CG-CB 4.36Å; E85-N433 WeakPolarHBondContact CG-ND2 3.23Å; Q157-N433 WeakPolarHBondContact CG-OD1 3.39Å; Q157-N433 PolarHBondContact NE2-O 3.24Å; Q157-N433 PolarHBondContact NE2-OD1 2.99Å; T430-N433 WeakPolarHBondContact O-CB 3.41Å; T430-N433 PolarHBondContact O-N 3.49Å; N433-F435 VanDerWaalsContact C-N 3.35Å; N433-F435 PolarHBondContact O-N 3.26Å; N433-L436 PolarHBondContact O-N 3.37Å; N433-L436 VanDerWaalsContact O-N 3.17Å; N433-N437 PolarHBondContact O-N 2.96Å
434	D	74.3	Confident	75.2	Confident	53 Å²	53	39.3 Å²	39.3	28%	0.283	21%	0.209	S	C	.	.	H	α-helix	trans	-60.4	-46.1	175.4	-68.1	-7.8	0	0	0	111.4	Q89 T430 L436 N437 V438	Q89-D434 VanDerWaalsContact NE2-CG 3.29Å; Q89-D434 PolarHBondContact NE2-OD1 2.94Å; Q89-D434 PolarHBondContact NE2-OD2 3.35Å; Q89-D434 VanDerWaalsContact NE2-OD2 3.17Å; Q89-D434 PolarHBondContact OE1-OD1 2.85Å; T430-D434 PolarHBondContact O-N 2.97Å; D434-L436 VanDerWaalsContact C-N 3.3Å; D434-L436 PolarHBondContact O-N 3.14Å; D434-N437 PolarHBondContact O-N 3.38Å; D434-V438 WeakPolarHBondContact O-CG2 3.5Å; D434-V438 PolarHBondContact O-N 2.94Å; D434-V438 VanDerWaalsContact O-N 3.1Å
435	F	78.7	Confident	76.4	Confident	110 Å²	110	34.8 Å²	34.8	48%	0.482	19%	0.188	S	C	.	.	H	α-helix	trans	-60.7	-40.7	175.4	177.1	-98	0	0	0	112.1	G431 M432 N433 V438 L439	G431-F435 PolarHBondContact O-N 2.86Å; M432-F435 PolarHBondContact O-N 3.46Å; N433-F435 VanDerWaalsContact C-N 3.35Å; N433-F435 PolarHBondContact O-N 3.26Å; F435-V438 PolarHBondContact O-N 3.07Å; F435-L439 HydrophobicContact CE1-CD1 4.38Å; F435-L439 PolarHBondContact O-N 3.01Å
436	L	83.6	Confident	77.8	Confident	7 Å²	7	29 Å²	29	4%	0.037	16%	0.157	C	C	.	.	H	α-helix	trans	-65	-38.1	177.6	-70.8	169.1	0	0	0	111.8	M156 Q157 I160 M432 N433 D434 L439 Q440	M156-L436 HydrophobicContact CB-CD1 3.67Å; M156-L436 HydrophobicContact CE-CD1 4.34Å; M156-L436 HydrophobicContact SD-CD2 4.27Å; Q157-L436 HydrophobicContact CG-CB 3.72Å; Q157-L436 HydrophobicContact CG-CD1 3.59Å; Q157-L436 HydrophobicContact CG-CG 4.28Å; I160-L436 HydrophobicContact CD1-CD1 4.23Å; M432-L436 HydrophobicContact CG-CD1 4.06Å; M432-L436 HydrophobicContact CG-CG 4.39Å; M432-L436 WeakPolarHBondContact O-CB 3.29Å; M432-L436 WeakPolarHBondContact O-CG 3.39Å; M432-L436 PolarHBondContact O-N 2.97Å; N433-L436 PolarHBondContact O-N 3.37Å; N433-L436 VanDerWaalsContact O-N 3.17Å; D434-L436 VanDerWaalsContact C-N 3.3Å; D434-L436 PolarHBondContact O-N 3.14Å; L436-L439 CarbonylContact O-C 3.54Å; L436-L439 WeakPolarHBondContact O-CB 3.34Å; L436-L439 PolarHBondContact O-N 3.5Å; L436-Q440 WeakPolarHBondContact O-CG 3.46Å; L436-Q440 PolarHBondContact O-N 2.91Å
437	N	81.7	Confident	79.5	Confident	8 Å²	8	27 Å²	27	4%	0.043	15%	0.145	C	C	.	.	H	α-helix	trans	-62.7	-41.8	173.2	-80.8	-24.2	0	0	0	112.3	G82 Q157 N433 D434 L439 Q440 S441	G82-N437 PolarHBondContact O-ND2 2.78Å; G82-N437 VanDerWaalsContact O-ND2 3.09Å; Q157-N437 PolarHBondContact NE2-OD1 3.35Å; N433-N437 PolarHBondContact O-N 2.96Å; D434-N437 PolarHBondContact O-N 3.38Å; N437-L439 VanDerWaalsContact C-N 3.32Å; N437-L439 PolarHBondContact O-N 2.88Å; N437-Q440 PolarHBondContact O-N 3.24Å; N437-S441 PolarHBondContact O-N 3.46Å
438	V	78.5	Confident	81.1	Confident	20 Å²	20	22.7 Å²	22.7	12%	0.121	12%	0.122	C	C	.	.	H	α-helix	trans	-62.6	-42.4	172.8	177.7	0	0	0	0	110.6	D434 F435 Q440 S441 L442 F488 Y492	D434-V438 WeakPolarHBondContact O-CG2 3.5Å; D434-V438 PolarHBondContact O-N 2.94Å; D434-V438 VanDerWaalsContact O-N 3.1Å; F435-V438 PolarHBondContact O-N 3.07Å; V438-Q440 VanDerWaalsContact C-N 3.34Å; V438-Q440 PolarHBondContact O-N 2.84Å; V438-S441 WeakPolarHBondContact O-CB 3.31Å; V438-S441 PolarHBondContact O-N 3.47Å; V438-L442 WeakPolarHBondContact O-CG 3.37Å; V438-L442 PolarHBondContact O-N 3.22Å; V438-F488 HydrophobicContact CG1-CD1 3.94Å; V438-F488 HydrophobicContact CG1-CE1 4.41Å; V438-F488 HydrophobicContact CG2-CE1 4.24Å; V438-Y492 HydrophobicContact CG1-CE2 3.88Å
439	L	84	Confident	82.5	Confident	29 Å²	29	18 Å²	18	15%	0.152	10%	0.1	C	C	.	.	H	α-helix	trans	-58.7	-44.3	175	-178.8	143.9	0	0	0	111.1	L149 F435 L436 N437 S441 L442 Q443	L149-L439 HydrophobicContact CD2-CD1 4.41Å; L149-L439 HydrophobicContact CG-CD1 4.43Å; L149-L439 HydrophobicContact CG-CD2 4.48Å; F435-L439 HydrophobicContact CE1-CD1 4.38Å; F435-L439 PolarHBondContact O-N 3.01Å; L436-L439 CarbonylContact O-C 3.54Å; L436-L439 WeakPolarHBondContact O-CB 3.34Å; L436-L439 PolarHBondContact O-N 3.5Å; N437-L439 VanDerWaalsContact C-N 3.32Å; N437-L439 PolarHBondContact O-N 2.88Å; L439-S441 VanDerWaalsContact C-N 3.32Å; L439-S441 PolarHBondContact O-N 3.16Å; L439-L442 PolarHBondContact O-N 3.02Å; L439-L442 VanDerWaalsContact O-N 3.16Å; L439-Q443 HydrophobicContact CD2-CG 4.22Å; L439-Q443 VanDerWaalsContact O-CG 3.32Å; L439-Q443 WeakPolarHBondContact O-CG 3.32Å; L439-Q443 PolarHBondContact O-N 3.19Å
440	Q	86.2	Confident	83.9	Confident	0 Å²	0	17.7 Å²	17.7	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-58.5	-43.1	175	-64.7	-53.2	-31.6	0	0	112.1	A150 S154 L436 N437 V438 L442 Q443 L444	A150-Q440 PolarHBondContact O-NE2 3.04Å; A150-Q440 PolarHBondContact O-OE1 3.29Å; S154-Q440 VanDerWaalsContact N-NE2 3.18Å; L436-Q440 WeakPolarHBondContact O-CG 3.46Å; L436-Q440 PolarHBondContact O-N 2.91Å; N437-Q440 PolarHBondContact O-N 3.24Å; V438-Q440 VanDerWaalsContact C-N 3.34Å; V438-Q440 PolarHBondContact O-N 2.84Å; Q440-L442 VanDerWaalsContact C-N 3.34Å; Q440-L442 PolarHBondContact O-N 3.5Å; Q440-Q443 PolarHBondContact O-N 3.32Å; Q440-Q443 VanDerWaalsContact O-N 3.08Å; Q440-L444 PolarHBondContact O-N 3.01Å
441	S	84.4	Confident	85.5	Confident	5 Å²	5	17.1 Å²	17.1	4%	0.035	10%	0.095	C	C	.	.	H	α-helix	trans	-58.5	-45.6	175.1	-173.2	0	0	0	0	111.5	N437 V438 L439 Q443 L444 N485	N437-S441 PolarHBondContact O-N 3.46Å; V438-S441 WeakPolarHBondContact O-CB 3.31Å; V438-S441 PolarHBondContact O-N 3.47Å; L439-S441 VanDerWaalsContact C-N 3.32Å; L439-S441 PolarHBondContact O-N 3.16Å; S441-Q443 PolarHBondContact O-N 2.95Å; S441-L444 VanDerWaalsContact O-CB 3.29Å; S441-L444 WeakPolarHBondContact O-CB 3.47Å; S441-L444 PolarHBondContact O-N 2.92Å; S441-L444 VanDerWaalsContact O-N 3.17Å; S441-N485 PolarHBondContact O-ND2 2.91Å; S441-N485 PolarHBondContact O-OD1 3.25Å; S441-N485 PolarHBondContact OG-OD1 3.04Å
442	L	85.9	Confident	86.6	Confident	44 Å²	44	15.5 Å²	15.5	23%	0.23	8%	0.077	C	C	.	.	H	α-helix	trans	-62.5	-28.2	176.7	-67	175.6	0	0	0	112.8	V438 L439 Q440 P445 N485 V489 Y512	V438-L442 WeakPolarHBondContact O-CG 3.37Å; V438-L442 PolarHBondContact O-N 3.22Å; L439-L442 PolarHBondContact O-N 3.02Å; L439-L442 VanDerWaalsContact O-N 3.16Å; Q440-L442 VanDerWaalsContact C-N 3.34Å; Q440-L442 PolarHBondContact O-N 3.5Å; L442-P445 WeakPolarHBondContact O-CD 3.34Å; L442-N485 HydrophobicContact CD2-CB 3.96Å; L442-V489 HydrophobicContact CD2-CG2 3.87Å; L442-Y512 WeakPolarHBondContact O-CE2 3.47Å; L442-Y512 PolarHBondContact O-OH 3.41Å
443	Q	91.3	Very high	87.5	Confident	11 Å²	11	14.4 Å²	14.4	5%	0.051	7%	0.072	C	C	.	.	H	α-helix	trans	-81.6	-15.8	178.8	-62.3	-53.9	-33.4	0	0	113.6	M146 A150 P260 L439 Q440 S441 P445 F446	M146-Q443 VanDerWaalsContact CB-OE1 3.28Å; M146-Q443 PolarHBondContact O-OE1 3.5Å; M146-Q443 VanDerWaalsContact O-OE1 3.11Å; A150-Q443 HydrophobicContact CB-CB 3.88Å; A150-Q443 HydrophobicContact CB-CG 3.89Å; P260-Q443 HydrophobicContact CB-CB 4.47Å; P260-Q443 HydrophobicContact CG-CB 3.75Å; L439-Q443 HydrophobicContact CD2-CG 4.22Å; L439-Q443 VanDerWaalsContact O-CG 3.32Å; L439-Q443 WeakPolarHBondContact O-CG 3.32Å; L439-Q443 PolarHBondContact O-N 3.19Å; Q440-Q443 PolarHBondContact O-N 3.32Å; Q440-Q443 VanDerWaalsContact O-N 3.08Å; S441-Q443 PolarHBondContact O-N 2.95Å; Q443-P445 VanDerWaalsContact C-CD 3.46Å; Q443-F446 WeakPolarHBondContact O-CB 3.18Å; Q443-F446 PolarHBondContact O-N 2.92Å; Q443-F446 VanDerWaalsContact O-N 3.16Å; Q443-F446 VanDerWaalsContact OE1-CD2 3.22Å
444	L	90.1	Very high	88.3	Confident	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.073	C	C	.	.	T	Hydrogen-bonded Turn	trans	-51	-46.9	-177.1	-83.7	174.6	0	0	0	115.8	I258 P260 Q440 S441 F446 A447 L448 V481	I258-L444 HydrophobicContact CB-CD2 3.99Å; I258-L444 HydrophobicContact CG2-CD2 3.61Å; I258-L444 WeakPolarHBondContact O-CD2 3.35Å; P260-L444 HydrophobicContact CG-CD2 4.08Å; P260-L444 HydrophobicContact CG-CG 4.35Å; Q440-L444 PolarHBondContact O-N 3.01Å; S441-L444 VanDerWaalsContact O-CB 3.29Å; S441-L444 WeakPolarHBondContact O-CB 3.47Å; S441-L444 PolarHBondContact O-N 2.92Å; S441-L444 VanDerWaalsContact O-N 3.17Å; L444-F446 PolarHBondContact O-N 2.92Å; L444-F446 VanDerWaalsContact O-N 3.08Å; L444-A447 PolarHBondContact O-N 3.03Å; L444-L448 HydrophobicContact CB-CD1 4.14Å; L444-L448 HydrophobicContact CD2-CD1 4.36Å; L444-L448 HydrophobicContact CD2-CG 4.47Å; L444-L448 VanDerWaalsContact O-CG 3.31Å; L444-L448 WeakPolarHBondContact O-CG 3.32Å; L444-L448 PolarHBondContact O-N 3.01Å; L444-V481 HydrophobicContact CB-CG1 3.7Å; L444-V481 HydrophobicContact CD1-CG1 4.03Å
445	P	92.7	Very high	89.1	Confident	1 Å²	1	12 Å²	12	1%	0.006	6%	0.059	C	C	.	.	H	α-helix	trans	-56.4	-31.3	-177.4	-26.7	37.2	0	0	0	113.1	L442 Q443 A447 L448 I449 V481 N485 I516	L442-P445 WeakPolarHBondContact O-CD 3.34Å; Q443-P445 VanDerWaalsContact C-CD 3.46Å; P445-A447 VanDerWaalsContact C-N 3.27Å; P445-A447 PolarHBondContact O-N 3.02Å; P445-L448 PolarHBondContact O-N 3.48Å; P445-I449 HydrophobicContact CB-CD1 3.94Å; P445-I449 VanDerWaalsContact O-CB 3.29Å; P445-I449 WeakPolarHBondContact O-CB 3.28Å; P445-I449 VanDerWaalsContact O-CG1 3.24Å; P445-I449 WeakPolarHBondContact O-CG1 3.14Å; P445-I449 PolarHBondContact O-N 3.28Å; P445-V481 HydrophobicContact CG-CG1 4.3Å; P445-N485 WeakPolarHBondContact CD-ND2 2.95Å; P445-I516 HydrophobicContact CB-CD1 3.83Å; P445-I516 HydrophobicContact CB-CG1 4.17Å; P445-I516 HydrophobicContact CG-CD1 3.84Å
446	F	93.8	Very high	89.7	Confident	0 Å²	0	6.9 Å²	6.9	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-72.2	-16	-179.8	-58.9	-51.6	0	0	0	114	L143 M146 I147 Y264 Q443 L444 P450 Y512 F515 I516 L519	L143-F446 HydrophobicContact CD1-CB 3.58Å; L143-F446 HydrophobicContact CD1-CD1 4Å; L143-F446 HydrophobicContact CD1-CG 4.12Å; L143-F446 WeakPolarHBondContact CD1-O 3.38Å; M146-F446 HydrophobicContact CB-CB 4.43Å; M146-F446 HydrophobicContact CB-CD2 3.62Å; M146-F446 HydrophobicContact CB-CE2 3.98Å; M146-F446 HydrophobicContact CB-CG 3.99Å; M146-F446 HydrophobicContact CG-CD2 3.85Å; M146-F446 HydrophobicContact CG-CE1 4.46Å; M146-F446 HydrophobicContact CG-CE2 3.66Å; M146-F446 HydrophobicContact CG-CG 4.3Å; M146-F446 HydrophobicContact CG-CZ 4.01Å; M146-F446 HydrophobicContact SD-CD2 4.39Å; M146-F446 HydrophobicContact SD-CE2 3.78Å; M146-F446 HydrophobicContact SD-CZ 4.27Å; I147-F446 HydrophobicContact CD1-CB 3.89Å; Y264-F446 PolarHBondContact OH-O 3.13Å; Q443-F446 WeakPolarHBondContact O-CB 3.18Å; Q443-F446 PolarHBondContact O-N 2.92Å; Q443-F446 VanDerWaalsContact O-N 3.16Å; Q443-F446 VanDerWaalsContact OE1-CD2 3.22Å; L444-F446 PolarHBondContact O-N 2.92Å; L444-F446 VanDerWaalsContact O-N 3.08Å; F446-P450 WeakPolarHBondContact O-CD 3.48Å; F446-P450 WeakPolarHBondContact O-CG 3.06Å; F446-Y512 AromaticContact CE2-CD2 3.94Å; F446-Y512 HydrophobicContact CE2-CD2 3.94Å; F446-Y512 AromaticContact CE2-CE2 3.53Å; F446-Y512 HydrophobicContact CE2-CE2 3.53Å; F446-Y512 AromaticContact CZ-CD2 3.63Å; F446-Y512 HydrophobicContact CZ-CD2 3.63Å; F446-Y512 AromaticContact CZ-CE2 3.53Å; F446-Y512 HydrophobicContact CZ-CE2 3.53Å; F446-F515 HydrophobicContact CD1-CD1 4.02Å; F446-F515 AromaticContact CD1-CE1 3.81Å; F446-F515 HydrophobicContact CD1-CE1 3.81Å; F446-F515 AromaticContact CE1-CD1 3.28Å; F446-F515 HydrophobicContact CE1-CD1 3.28Å; F446-F515 AromaticContact CE1-CE1 3.55Å; F446-F515 HydrophobicContact CE1-CE1 3.55Å; F446-F515 HydrophobicContact CE1-CG 4.3Å; F446-F515 AromaticContact CZ-CD1 3.92Å; F446-F515 HydrophobicContact CZ-CD1 3.92Å; F446-F515 HydrophobicContact CZ-CE1 4.39Å; F446-I516 HydrophobicContact CE1-CG1 3.87Å; F446-I516 HydrophobicContact CZ-CD1 4.44Å; F446-I516 HydrophobicContact CZ-CG1 4.07Å; F446-L519 HydrophobicContact CD1-CD1 3.74Å; F446-L519 HydrophobicContact CE1-CD1 4.21Å
447	A	93.3	Very high	89.9	Confident	0 Å²	0	8.5 Å²	8.5	0%	0	5%	0.046	C	C	.	.	H	α-helix	trans	-99.3	-42.3	169.2	0	0	0	0	0	111.6	P260 I263 Y264 L444 P445 P450 I451	P260-A447 HydrophobicContact CB-CB 3.69Å; P260-A447 WeakPolarHBondContact O-CB 3.4Å; I263-A447 HydrophobicContact CB-CB 4.31Å; I263-A447 HydrophobicContact CD1-CB 3.91Å; Y264-A447 HydrophobicContact CD2-CB 4.33Å; Y264-A447 HydrophobicContact CE2-CB 3.72Å; L444-A447 PolarHBondContact O-N 3.03Å; P445-A447 VanDerWaalsContact C-N 3.27Å; P445-A447 PolarHBondContact O-N 3.02Å; A447-P450 WeakPolarHBondContact O-CD 3.3Å; A447-I451 VanDerWaalsContact O-CG2 3.26Å; A447-I451 WeakPolarHBondContact O-CG2 2.99Å; A447-I451 PolarHBondContact O-N 3.1Å
448	L	93.3	Very high	90.2	Very high	2 Å²	2	12.9 Å²	12.9	1%	0.01	7%	0.073	C	C	.	.	H	α-helix	trans	-68.9	-41.4	-174	-61.7	179.1	0	0	0	113.4	L112 I258 I263 L444 P445 I451 L452 I478 V481	L112-L448 HydrophobicContact CD1-CD2 3.34Å; L112-L448 HydrophobicContact CD2-CD2 3.63Å; L112-L448 HydrophobicContact CG-CD2 4.03Å; I258-L448 HydrophobicContact CG2-CD2 4.37Å; I263-L448 HydrophobicContact CD1-CD2 3.64Å; L444-L448 HydrophobicContact CB-CD1 4.14Å; L444-L448 HydrophobicContact CD2-CD1 4.36Å; L444-L448 HydrophobicContact CD2-CG 4.47Å; L444-L448 VanDerWaalsContact O-CG 3.31Å; L444-L448 WeakPolarHBondContact O-CG 3.32Å; L444-L448 PolarHBondContact O-N 3.01Å; P445-L448 PolarHBondContact O-N 3.48Å; L448-I451 VanDerWaalsContact O-CG2 3.29Å; L448-I451 WeakPolarHBondContact O-CG2 3.36Å; L448-L452 WeakPolarHBondContact O-CB 3.34Å; L448-L452 PolarHBondContact O-N 3.4Å; L448-L452 VanDerWaalsContact O-N 3.14Å; L448-I478 HydrophobicContact CB-CG1 3.94Å; L448-V481 HydrophobicContact CD1-CB 4.22Å; L448-V481 HydrophobicContact CD1-CG1 4.06Å; L448-V481 HydrophobicContact CD1-CG2 3.88Å
449	I	93.6	Very high	90.6	Very high	0 Å²	0	15.1 Å²	15.1	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-67.7	-50.5	-178.1	-61.4	167.6	0	0	0	110.8	P445 I451 L452 T453 I478 I516 L519 A520 C523	P445-I449 HydrophobicContact CB-CD1 3.94Å; P445-I449 VanDerWaalsContact O-CB 3.29Å; P445-I449 WeakPolarHBondContact O-CB 3.28Å; P445-I449 VanDerWaalsContact O-CG1 3.24Å; P445-I449 WeakPolarHBondContact O-CG1 3.14Å; P445-I449 PolarHBondContact O-N 3.28Å; I449-I451 PolarHBondContact O-N 3.23Å; I449-L452 PolarHBondContact O-N 2.75Å; I449-T453 WeakPolarHBondContact O-CB 3.33Å; I449-T453 PolarHBondContact O-N 2.04Å; I449-T453 PolarHBondContact O-OG1 3.43Å; I449-I478 HydrophobicContact CD1-CG2 4.35Å; I449-I478 HydrophobicContact CG1-CD1 4.17Å; I449-I478 HydrophobicContact CG1-CG2 3.76Å; I449-I516 HydrophobicContact CD1-CG2 4.21Å; I449-L519 HydrophobicContact CB-CB 4.4Å; I449-L519 HydrophobicContact CD1-CB 4.21Å; I449-L519 HydrophobicContact CG2-CB 3.82Å; I449-L519 WeakPolarHBondContact CG2-O 3.36Å; I449-A520 HydrophobicContact CD1-CB 4.45Å; I449-C523 HydrophobicContact CG2-CB 3.71Å
450	P	94.2	Very high	90.7	Very high	0 Å²	0	14.7 Å²	14.7	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-60.8	-43.5	177.4	-27	37.9	0	0	0	113.2	L127 Y135 L143 F446 A447 L452 T453 F454	L127-P450 HydrophobicContact CD1-CB 4.19Å; Y135-P450 HydrophobicContact CE2-CB 4.4Å; Y135-P450 HydrophobicContact CE2-CG 4.37Å; L143-P450 HydrophobicContact CD2-CG 3.96Å; F446-P450 WeakPolarHBondContact O-CD 3.48Å; F446-P450 WeakPolarHBondContact O-CG 3.06Å; A447-P450 WeakPolarHBondContact O-CD 3.3Å; P450-L452 PolarHBondContact O-N 2.97Å; P450-T453 PolarHBondContact O-N 3.31Å; P450-F454 HydrophobicContact CB-CD2 4.24Å; P450-F454 HydrophobicContact CB-CE2 3.9Å; P450-F454 WeakPolarHBondContact O-CD2 3.28Å; P450-F454 WeakPolarHBondContact O-CG 3.38Å; P450-F454 PolarHBondContact O-N 3.08Å
451	I	94.6	Very high	90.9	Very high	0 Å²	0	14.7 Å²	14.7	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-64.3	-41.7	-177.7	-169.1	58.8	0	0	0	111.7	L115 A116 L119 L127 I263 A447 L448 I449 T455	L115-I451 HydrophobicContact CB-CG1 3.89Å; A116-I451 HydrophobicContact CB-CD1 4.49Å; L119-I451 HydrophobicContact CB-CD1 3.95Å; L119-I451 HydrophobicContact CD2-CD1 3.69Å; L119-I451 HydrophobicContact CG-CD1 4.4Å; L127-I451 HydrophobicContact CD1-CB 4.41Å; L127-I451 HydrophobicContact CD1-CD1 4.12Å; L127-I451 HydrophobicContact CD2-CB 4.1Å; L127-I451 HydrophobicContact CD2-CD1 4.39Å; I263-I451 HydrophobicContact CG2-CB 4.11Å; I263-I451 HydrophobicContact CG2-CG1 4.15Å; I263-I451 HydrophobicContact CG2-CG2 4.24Å; A447-I451 VanDerWaalsContact O-CG2 3.26Å; A447-I451 WeakPolarHBondContact O-CG2 2.99Å; A447-I451 PolarHBondContact O-N 3.1Å; L448-I451 VanDerWaalsContact O-CG2 3.29Å; L448-I451 WeakPolarHBondContact O-CG2 3.36Å; I449-I451 PolarHBondContact O-N 3.23Å; I451-T455 HydrophobicContact CD1-CG2 3.88Å; I451-T455 HydrophobicContact CG1-CG2 4.36Å; I451-T455 WeakPolarHBondContact O-CB 3.41Å; I451-T455 VanDerWaalsContact O-CG2 3.27Å; I451-T455 WeakPolarHBondContact O-CG2 3.34Å; I451-T455 PolarHBondContact O-N 2.92Å; I451-T455 VanDerWaalsContact O-N 3.08Å; I451-T455 PolarHBondContact O-OG1 3.25Å
452	L	93.9	Very high	91	Very high	4 Å²	4	19.5 Å²	19.5	2%	0.021	11%	0.113	C	C	.	.	H	α-helix	trans	-67.7	-40.6	176.7	-174.7	65	0	0	0	111.5	L115 L448 I449 P450 T455 S456 G474 I478	L115-L452 HydrophobicContact CD1-CD1 4.35Å; L448-L452 WeakPolarHBondContact O-CB 3.34Å; L448-L452 PolarHBondContact O-N 3.4Å; L448-L452 VanDerWaalsContact O-N 3.14Å; I449-L452 PolarHBondContact O-N 2.75Å; P450-L452 PolarHBondContact O-N 2.97Å; L452-T455 PolarHBondContact O-OG1 3.29Å; L452-S456 WeakPolarHBondContact O-CB 3.46Å; L452-S456 PolarHBondContact O-N 2.74Å; L452-S456 VanDerWaalsContact O-N 3.12Å; L452-S456 PolarHBondContact O-OG 3.02Å; L452-G474 VanDerWaalsContact CD2-C 3.43Å; L452-I478 HydrophobicContact CB-CD1 3.87Å; L452-I478 HydrophobicContact CD2-CD1 3.44Å; L452-I478 VanDerWaalsContact CD2-CD1 3.44Å; L452-I478 HydrophobicContact CG-CD1 4.3Å
453	T	91.9	Very high	91	Very high	6 Å²	6	23 Å²	23	4%	0.037	13%	0.132	C	C	.	.	H	α-helix	trans	-57.1	-57.8	178.3	-58.7	0	0	0	0	110.3	I449 P450 T455 S456 L457 C523 A526	I449-T453 WeakPolarHBondContact O-CB 3.33Å; I449-T453 PolarHBondContact O-N 2.04Å; I449-T453 PolarHBondContact O-OG1 3.43Å; P450-T453 PolarHBondContact O-N 3.31Å; T453-T455 PolarHBondContact O-N 3.17Å; T453-S456 PolarHBondContact O-N 2.97Å; T453-S456 VanDerWaalsContact O-N 3.14Å; T453-L457 HydrophobicContact CG2-CD1 4.35Å; T453-L457 WeakPolarHBondContact O-CG 3.46Å; T453-L457 PolarHBondContact O-N 3.45Å; T453-C523 WeakPolarHBondContact OG1-CA 3.37Å; T453-C523 WeakPolarHBondContact OG1-CB 3.39Å; T453-C523 PolarHBondContact OG1-SG 3.32Å; T453-C523 VanDerWaalsContact OG1-SG 3.39Å; T453-A526 HydrophobicContact CG2-CB 3.7Å
454	F	93.3	Very high	91	Very high	5 Å²	5	24.5 Å²	24.5	2%	0.022	14%	0.138	C	C	.	.	H	α-helix	trans	-72.5	-32.7	-173.3	-59.2	-46.3	0	0	0	113.3	L119 L127 V130 Q134 Y135 P450 S456 L457 I460 M461	L119-F454 HydrophobicContact CD1-CB 4.05Å; L127-F454 HydrophobicContact CD1-CD2 3.82Å; L127-F454 HydrophobicContact CD1-CE2 4.35Å; V130-F454 HydrophobicContact CB-CD2 4.37Å; V130-F454 HydrophobicContact CG1-CB 4.11Å; V130-F454 HydrophobicContact CG1-CD1 3.96Å; V130-F454 HydrophobicContact CG1-CD2 3.66Å; V130-F454 HydrophobicContact CG1-CE1 4.3Å; V130-F454 HydrophobicContact CG1-CE2 4Å; V130-F454 HydrophobicContact CG1-CG 3.64Å; V130-F454 HydrophobicContact CG1-CZ 4.32Å; Q134-F454 HydrophobicContact CB-CE1 3.51Å; Q134-F454 HydrophobicContact CB-CZ 3.68Å; Q134-F454 HydrophobicContact CG-CD1 4.24Å; Q134-F454 HydrophobicContact CG-CE1 3.65Å; Q134-F454 HydrophobicContact CG-CZ 4.13Å; Y135-F454 HydrophobicContact CD2-CZ 4.16Å; Y135-F454 AromaticContact CE2-CE2 3.98Å; Y135-F454 HydrophobicContact CE2-CE2 3.98Å; Y135-F454 AromaticContact CE2-CZ 3.6Å; Y135-F454 HydrophobicContact CE2-CZ 3.6Å; Y135-F454 AromaticContact CZ-CZ 3.84Å; P450-F454 HydrophobicContact CB-CD2 4.24Å; P450-F454 HydrophobicContact CB-CE2 3.9Å; P450-F454 WeakPolarHBondContact O-CD2 3.28Å; P450-F454 WeakPolarHBondContact O-CG 3.38Å; P450-F454 PolarHBondContact O-N 3.08Å; F454-S456 PolarHBondContact O-N 3.4Å; F454-L457 HydrophobicContact CD1-CD1 4.11Å; F454-L457 PolarHBondContact O-N 2.92Å; F454-I460 HydrophobicContact CB-CD1 4.01Å; F454-I460 HydrophobicContact CD1-CD1 3.45Å; F454-I460 VanDerWaalsContact CD1-CD1 3.45Å; F454-I460 HydrophobicContact CE1-CD1 4.29Å; F454-I460 HydrophobicContact CG-CD1 4.05Å; F454-M461 WeakPolarHBondContact O-CG 3.45Å
455	T	92.9	Very high	91	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-73.4	-13.7	174.1	58.2	0	0	0	0	113.4	L115 L119 I451 L452 T453 M461 N466	L115-T455 HydrophobicContact CB-CG2 4.22Å; L119-T455 HydrophobicContact CB-CG2 3.99Å; L119-T455 HydrophobicContact CD1-CG2 4.17Å; I451-T455 HydrophobicContact CD1-CG2 3.88Å; I451-T455 HydrophobicContact CG1-CG2 4.36Å; I451-T455 WeakPolarHBondContact O-CB 3.41Å; I451-T455 VanDerWaalsContact O-CG2 3.27Å; I451-T455 WeakPolarHBondContact O-CG2 3.34Å; I451-T455 PolarHBondContact O-N 2.92Å; I451-T455 VanDerWaalsContact O-N 3.08Å; I451-T455 PolarHBondContact O-OG1 3.25Å; L452-T455 PolarHBondContact O-OG1 3.29Å; T453-T455 PolarHBondContact O-N 3.17Å; T455-M461 HydrophobicContact CG2-SD 4.41Å; T455-N466 WeakPolarHBondContact CB-ND2 3.31Å; T455-N466 VanDerWaalsContact O-CG 3.28Å; T455-N466 PolarHBondContact O-N 2.9Å; T455-N466 PolarHBondContact O-ND2 3.45Å; T455-N466 PolarHBondContact OG1-ND2 3.43Å
456	S	90.4	Very high	90.9	Very high	2 Å²	2	26 Å²	26	1%	0.014	15%	0.15	C	C	.	.	H	α-helix	trans	-95.3	-15.5	177.6	-62.6	0	0	0	0	114.1	L452 T453 F454 K471	L452-S456 WeakPolarHBondContact O-CB 3.46Å; L452-S456 PolarHBondContact O-N 2.74Å; L452-S456 VanDerWaalsContact O-N 3.12Å; L452-S456 PolarHBondContact O-OG 3.02Å; T453-S456 PolarHBondContact O-N 2.97Å; T453-S456 VanDerWaalsContact O-N 3.14Å; F454-S456 PolarHBondContact O-N 3.4Å; S456-K471 PolarHBondContact O-NZ 3.1Å; S456-K471 VanDerWaalsContact O-NZ 3.12Å
457	L	88.7	Confident	90.6	Very high	41 Å²	41	28 Å²	28	22%	0.215	17%	0.17	C	C	.	.			trans	-81.7	124.6	178.4	-74.7	170.4	0	0	0	111.4	T453 F454 S459 I460 M461 A526	T453-L457 HydrophobicContact CG2-CD1 4.35Å; T453-L457 WeakPolarHBondContact O-CG 3.46Å; T453-L457 PolarHBondContact O-N 3.45Å; F454-L457 HydrophobicContact CD1-CD1 4.11Å; F454-L457 PolarHBondContact O-N 2.92Å; L457-S459 VanDerWaalsContact C-N 3.3Å; L457-S459 PolarHBondContact O-N 3.37Å; L457-I460 HydrophobicContact CB-CB 4.44Å; L457-I460 HydrophobicContact CB-CD1 4.33Å; L457-I460 HydrophobicContact CB-CG1 4.36Å; L457-I460 HydrophobicContact CD1-CD1 3.87Å; L457-I460 PolarHBondContact O-N 3.25Å; L457-M461 PolarHBondContact O-N 3.38Å; L457-A526 HydrophobicContact CD1-CB 4.35Å; L457-A526 HydrophobicContact CD2-CB 3.66Å; L457-A526 HydrophobicContact CG-CB 3.83Å
458	T	86.4	Confident	90.3	Very high	101 Å²	101	34.1 Å²	34.1	62%	0.62	20%	0.202	S	C	*	.	H	α-helix	trans	-69.9	-27.1	176.5	48.1	0	0	0	0	112.6	I460 N462 A465	T458-I460 VanDerWaalsContact C-N 3.27Å; T458-I460 PolarHBondContact O-N 3.19Å; T458-N462 WeakPolarHBondContact O-CA 3.35Å; T458-N462 PolarHBondContact O-N 2.86Å; T458-A465 HydrophobicContact CG2-CB 3.86Å
459	S	86.7	Confident	90.1	Very high	67 Å²	67	37.6 Å²	37.6	47%	0.469	23%	0.231	S	C	.	.	H	α-helix	trans	-64.7	-29.5	175.3	53.8	0	0	0	0	113.2	L457	L457-S459 VanDerWaalsContact C-N 3.3Å; L457-S459 PolarHBondContact O-N 3.37Å
460	I	87.8	Confident	89.9	Confident	19 Å²	19	41.1 Å²	41.1	10%	0.097	25%	0.245	C	C	.	.	H	α-helix	trans	-96.2	-46.6	-178.6	-62.4	176.6	0	0	0	110.8	L119 T123 V130 Q134 F454 L457 T458	L119-I460 HydrophobicContact CD1-CG2 4.16Å; T123-I460 HydrophobicContact CG2-CG2 3.46Å; T123-I460 VanDerWaalsContact CG2-CG2 3.46Å; V130-I460 HydrophobicContact CG1-CD1 4.1Å; Q134-I460 HydrophobicContact CG-CD1 4.13Å; F454-I460 HydrophobicContact CB-CD1 4.01Å; F454-I460 HydrophobicContact CD1-CD1 3.45Å; F454-I460 VanDerWaalsContact CD1-CD1 3.45Å; F454-I460 HydrophobicContact CE1-CD1 4.29Å; F454-I460 HydrophobicContact CG-CD1 4.05Å; L457-I460 HydrophobicContact CB-CB 4.44Å; L457-I460 HydrophobicContact CB-CD1 4.33Å; L457-I460 HydrophobicContact CB-CG1 4.36Å; L457-I460 HydrophobicContact CD1-CD1 3.87Å; L457-I460 PolarHBondContact O-N 3.25Å; T458-I460 VanDerWaalsContact C-N 3.27Å; T458-I460 PolarHBondContact O-N 3.19Å
461	M	88.9	Confident	89.6	Confident	0 Å²	0	43 Å²	43	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-90.9	-6.5	-173.9	-68.6	-68.8	-67.2	0	0	114.2	R118 L119 V122 T123 F454 T455 L457 D463 F464 A465	R118-M461 HydrophobicContact CB-CE 4.22Å; L119-M461 HydrophobicContact CD1-SD 4.03Å; V122-M461 HydrophobicContact CB-CE 4.1Å; V122-M461 HydrophobicContact CB-SD 4.15Å; V122-M461 HydrophobicContact CG1-CE 4.31Å; V122-M461 HydrophobicContact CG1-SD 4.18Å; V122-M461 HydrophobicContact CG2-CE 3.87Å; T123-M461 HydrophobicContact CG2-SD 4.44Å; F454-M461 WeakPolarHBondContact O-CG 3.45Å; T455-M461 HydrophobicContact CG2-SD 4.41Å; L457-M461 PolarHBondContact O-N 3.38Å; M461-D463 PolarHBondContact O-N 3.27Å; M461-F464 HydrophobicContact CE-CB 4.13Å; M461-F464 WeakPolarHBondContact CE-O 3.37Å; M461-F464 WeakPolarHBondContact O-CA 3.22Å; M461-F464 WeakPolarHBondContact O-CB 3.44Å; M461-F464 PolarHBondContact O-N 3.23Å; M461-A465 HydrophobicContact CB-CB 4.1Å
462	N	86.5	Confident	89.4	Confident	107 Å²	107	47.6 Å²	47.6	57%	0.572	28%	0.277	S	S	*	.	G	3₁₀ helix	trans	49.4	-131.6	-173.5	-62.6	-58.9	0	0	0	111	T458 F464 A465	T458-N462 WeakPolarHBondContact O-CA 3.35Å; T458-N462 PolarHBondContact O-N 2.86Å; N462-F464 PolarHBondContact O-N 3.47Å; N462-F464 VanDerWaalsContact O-N 3.09Å; N462-A465 PolarHBondContact O-N 3.02Å
463	D	87.4	Confident	89.1	Confident	118 Å²	118	49.5 Å²	49.5	63%	0.631	29%	0.293	S	S	*	.	G	3₁₀ helix	trans	-65.4	-9.9	178.1	-59.7	-28.5	0	0	0	114.2	K280 M461	K280-D463 WeakPolarHBondContact CE-OD2 3.34Å; K280-D463 IonicContact NZ-OD2 3.48Å; K280-D463 PolarHBondContact NZ-OD2 2.94Å; M461-D463 PolarHBondContact O-N 3.27Å
464	F	90.1	Very high	89	Confident	42 Å²	42	49.8 Å²	49.8	18%	0.184	30%	0.296	C	S	.	.	G	3₁₀ helix	trans	-99.4	18.6	-179.2	-62.1	-82.6	0	0	0	112.7	R118 V122 K280 V283 K284 M461 N462	R118-F464 PolarHBondContact NH2-O 3.17Å; V122-F464 HydrophobicContact CG1-CB 4.24Å; V122-F464 HydrophobicContact CG1-CD2 4.18Å; V122-F464 HydrophobicContact CG2-CB 3.83Å; V122-F464 HydrophobicContact CG2-CD2 4.16Å; V122-F464 HydrophobicContact CG2-CG 4Å; K280-F464 HydrophobicContact CB-CZ 4.36Å; V283-F464 HydrophobicContact CB-CE2 4.18Å; V283-F464 HydrophobicContact CB-CZ 4Å; V283-F464 HydrophobicContact CG1-CD2 4.17Å; V283-F464 HydrophobicContact CG1-CE1 4.2Å; V283-F464 HydrophobicContact CG1-CE2 3.7Å; V283-F464 HydrophobicContact CG1-CZ 3.71Å; K284-F464 HydrophobicContact CB-CE1 4.24Å; M461-F464 HydrophobicContact CE-CB 4.13Å; M461-F464 WeakPolarHBondContact CE-O 3.37Å; M461-F464 WeakPolarHBondContact O-CA 3.22Å; M461-F464 WeakPolarHBondContact O-CB 3.44Å; M461-F464 PolarHBondContact O-N 3.23Å; N462-F464 PolarHBondContact O-N 3.47Å; N462-F464 VanDerWaalsContact O-N 3.09Å
465	A	90.3	Very high	88.8	Confident	26 Å²	26	50.7 Å²	50.7	22%	0.215	31%	0.308	C	S	.	.	P	Polyproline II helix	trans	-61.3	154.8	174.9	0	0	0	0	0	112.6	T458 M461 N462	T458-A465 HydrophobicContact CG2-CB 3.86Å; M461-A465 HydrophobicContact CB-CB 4.1Å; N462-A465 PolarHBondContact O-N 3.02Å
466	N	90	Very high	88.7	Confident	7 Å²	7	55.6 Å²	55.6	4%	0.037	33%	0.333	C	S	.	.	P	Polyproline II helix	trans	-64.8	134.9	177.1	-74.1	-19.2	0	0	0	112.3	R118 T455 W470 K471	R118-N466 PolarHBondContact NH1-OD1 3.4Å; T455-N466 WeakPolarHBondContact CB-ND2 3.31Å; T455-N466 VanDerWaalsContact O-CG 3.28Å; T455-N466 PolarHBondContact O-N 2.9Å; T455-N466 PolarHBondContact O-ND2 3.45Å; T455-N466 PolarHBondContact OG1-ND2 3.43Å; N466-W470 HydrophobicContact CB-CB 4.01Å; N466-K471 HydrophobicContact CB-CG 4.25Å; N466-K471 WeakPolarHBondContact O-CE 3.34Å
467	G	88.5	Confident	88.6	Confident	42 Å²	42	56.8 Å²	56.8	43%	0.433	34%	0.34	S	S	.	.	P	Polyproline II helix	trans	-70	165.2	169.6	0	0	0	0	0	112.5	A469 W470 K471	G467-A469 VanDerWaalsContact C-N 3.27Å; G467-A469 PolarHBondContact O-N 2.74Å; G467-W470 PolarHBondContact O-N 3.44Å; G467-K471 PolarHBondContact O-N 3.4Å; G467-K471 VanDerWaalsContact O-N 3.1Å
468	L	87.6	Confident	88.6	Confident	127 Å²	127	55.8 Å²	55.8	67%	0.665	33%	0.334	S	S	*	.	H	α-helix	trans	-55.9	-38.1	-175.9	-174.9	63.1	0	0	0	113.4	W470 K471 I472	L468-W470 PolarHBondContact O-N 3.08Å; L468-K471 WeakPolarHBondContact O-CB 3.41Å; L468-K471 PolarHBondContact O-N 2.79Å; L468-I472 HydrophobicContact CD1-CD1 4.16Å; L468-I472 HydrophobicContact CD1-CG1 4.34Å; L468-I472 HydrophobicContact CG-CD1 3.89Å; L468-I472 HydrophobicContact CG-CG1 4.46Å; L468-I472 WeakPolarHBondContact O-CG1 3.49Å; L468-I472 PolarHBondContact O-N 3.42Å
469	A	89.2	Confident	88.8	Confident	76 Å²	76	56.6 Å²	56.6	63%	0.628	33%	0.334	S	S	*	.	H	α-helix	trans	-60.7	-43.6	177.4	0	0	0	0	0	112.5	G467 I472 A473	G467-A469 VanDerWaalsContact C-N 3.27Å; G467-A469 PolarHBondContact O-N 2.74Å; A469-I472 PolarHBondContact O-N 2.69Å; A469-A473 VanDerWaalsContact O-CB 3.27Å; A469-A473 WeakPolarHBondContact O-CB 3.32Å; A469-A473 PolarHBondContact O-N 3.17Å
470	W	88.6	Confident	88.8	Confident	73 Å²	73	56.8 Å²	56.8	28%	0.277	33%	0.333	S	S	.	.	H	α-helix	trans	-68.3	-36.8	177.3	-76.1	103.7	0	0	0	112.2	L111 N466 G467 L468 G474	L111-W470 HydrophobicContact CB-CH2 4.37Å; L111-W470 HydrophobicContact CB-CZ3 3.94Å; L111-W470 HydrophobicContact CD1-CH2 3.98Å; L111-W470 HydrophobicContact CD1-CZ3 3.82Å; L111-W470 HydrophobicContact CD2-CH2 3.51Å; L111-W470 HydrophobicContact CD2-CZ3 3.96Å; L111-W470 HydrophobicContact CG-CH2 4.11Å; L111-W470 HydrophobicContact CG-CZ3 4.07Å; N466-W470 HydrophobicContact CB-CB 4.01Å; G467-W470 PolarHBondContact O-N 3.44Å; L468-W470 PolarHBondContact O-N 3.08Å; W470-G474 PolarHBondContact O-N 3.31Å
471	K	88.3	Confident	88.7	Confident	41 Å²	41	56.1 Å²	56.1	18%	0.178	33%	0.33	C	S	.	.	H	α-helix	trans	-60.2	-48.9	174.4	-72.1	-171.7	-178.7	-158.6	0	111.5	S456 N466 G467 L468 G475 L527	S456-K471 PolarHBondContact O-NZ 3.1Å; S456-K471 VanDerWaalsContact O-NZ 3.12Å; N466-K471 HydrophobicContact CB-CG 4.25Å; N466-K471 WeakPolarHBondContact O-CE 3.34Å; G467-K471 PolarHBondContact O-N 3.4Å; G467-K471 VanDerWaalsContact O-N 3.1Å; L468-K471 WeakPolarHBondContact O-CB 3.41Å; L468-K471 PolarHBondContact O-N 2.79Å; K471-G475 PolarHBondContact O-N 3.39Å; K471-L527 HydrophobicContact CB-CD2 3.59Å; K471-L527 HydrophobicContact CD-CD2 3.97Å; K471-L527 HydrophobicContact CG-CD2 3.69Å
472	I	89.3	Confident	88.5	Confident	96 Å²	96	57.7 Å²	57.7	49%	0.492	34%	0.34	S	S	.	.	H	α-helix	trans	-67.3	-49.3	179	-65.3	168.5	0	0	0	110.7	L468 A469 G474 G475 I476	L468-I472 HydrophobicContact CD1-CD1 4.16Å; L468-I472 HydrophobicContact CD1-CG1 4.34Å; L468-I472 HydrophobicContact CG-CD1 3.89Å; L468-I472 HydrophobicContact CG-CG1 4.46Å; L468-I472 WeakPolarHBondContact O-CG1 3.49Å; L468-I472 PolarHBondContact O-N 3.42Å; A469-I472 PolarHBondContact O-N 2.69Å; I472-G474 PolarHBondContact O-N 3.49Å; I472-G475 PolarHBondContact O-N 3.45Å; I472-I476 HydrophobicContact CG2-CD1 3.89Å; I472-I476 HydrophobicContact CG2-CG1 4.49Å; I472-I476 WeakPolarHBondContact O-CG1 3.49Å; I472-I476 PolarHBondContact O-N 3.14Å
473	A	89.1	Confident	88.5	Confident	44 Å²	44	55.3 Å²	55.3	36%	0.364	34%	0.335	S	S	.	.	H	α-helix	trans	-60.5	-46.3	-179.2	0	0	0	0	0	111.9	A469 G475 I476 V477	A469-A473 VanDerWaalsContact O-CB 3.27Å; A469-A473 WeakPolarHBondContact O-CB 3.32Å; A469-A473 PolarHBondContact O-N 3.17Å; A473-G475 VanDerWaalsContact C-N 3.34Å; A473-G475 PolarHBondContact O-N 2.92Å; A473-I476 PolarHBondContact O-N 3.49Å; A473-V477 WeakPolarHBondContact O-CG2 3.32Å; A473-V477 PolarHBondContact O-N 3.3Å
474	G	88.6	Confident	88.2	Confident	11 Å²	11	51.7 Å²	51.7	11%	0.113	32%	0.315	C	S	.	.	H	α-helix	trans	-62.2	-40.4	175.3	0	0	0	0	0	112.5	L452 W470 I472 I476 V477 I478	L452-G474 VanDerWaalsContact CD2-C 3.43Å; W470-G474 PolarHBondContact O-N 3.31Å; I472-G474 PolarHBondContact O-N 3.49Å; G474-I476 PolarHBondContact O-N 3.48Å; G474-V477 PolarHBondContact O-N 3.17Å; G474-I478 WeakPolarHBondContact O-CG1 3.49Å; G474-I478 PolarHBondContact O-N 2.92Å
475	G	89.8	Confident	87.9	Confident	25 Å²	25	49.8 Å²	49.8	26%	0.258	31%	0.307	S	S	.	.	H	α-helix	trans	-61.8	-40.9	175.6	0	0	0	0	0	112.9	K471 I472 A473 I478 L479	K471-G475 PolarHBondContact O-N 3.39Å; I472-G475 PolarHBondContact O-N 3.45Å; A473-G475 VanDerWaalsContact C-N 3.34Å; A473-G475 PolarHBondContact O-N 2.92Å; G475-I478 PolarHBondContact O-N 2.93Å; G475-L479 WeakPolarHBondContact O-CB 3.44Å; G475-L479 PolarHBondContact O-N 3.5Å
476	I	90.6	Very high	87.4	Confident	102 Å²	102	52 Å²	52	52%	0.523	31%	0.314	S	S	.	.	H	α-helix	trans	-63.1	-45.7	174.8	-68.1	167	0	0	0	110.7	I472 A473 G474 I478 L479 V480	I472-I476 HydrophobicContact CG2-CD1 3.89Å; I472-I476 HydrophobicContact CG2-CG1 4.49Å; I472-I476 WeakPolarHBondContact O-CG1 3.49Å; I472-I476 PolarHBondContact O-N 3.14Å; A473-I476 PolarHBondContact O-N 3.49Å; G474-I476 PolarHBondContact O-N 3.48Å; I476-I478 PolarHBondContact O-N 3.17Å; I476-L479 PolarHBondContact O-N 3.31Å; I476-V480 HydrophobicContact CG2-CG2 4.39Å; I476-V480 WeakPolarHBondContact O-CG2 3.31Å; I476-V480 PolarHBondContact O-N 3.28Å
477	V	88.9	Confident	87	Confident	28 Å²	28	57.7 Å²	57.7	17%	0.17	34%	0.336	C	S	.	.	H	α-helix	trans	-59.7	-47.4	178.4	171.1	0	0	0	0	111.1	I108 A473 G474 L479 V480 V481	I108-V477 HydrophobicContact CG2-CG1 3.83Å; I108-V477 HydrophobicContact CG2-CG2 4.13Å; A473-V477 WeakPolarHBondContact O-CG2 3.32Å; A473-V477 PolarHBondContact O-N 3.3Å; G474-V477 PolarHBondContact O-N 3.17Å; V477-L479 VanDerWaalsContact C-N 3.32Å; V477-L479 PolarHBondContact O-N 2.97Å; V477-V480 PolarHBondContact O-N 3.31Å; V477-V481 HydrophobicContact CG1-CG2 4.39Å; V477-V481 VanDerWaalsContact O-CG2 3.26Å; V477-V481 WeakPolarHBondContact O-CG2 3.41Å; V477-V481 PolarHBondContact O-N 3.05Å
478	I	89.2	Confident	86.2	Confident	19 Å²	19	56.4 Å²	56.4	10%	0.097	32%	0.318	C	S	.	.	H	α-helix	trans	-59.4	-44.6	176.4	-70.2	170.4	0	0	0	110.9	L448 I449 L452 G474 G475 I476 V480 V481 C482	L448-I478 HydrophobicContact CB-CG1 3.94Å; I449-I478 HydrophobicContact CD1-CG2 4.35Å; I449-I478 HydrophobicContact CG1-CD1 4.17Å; I449-I478 HydrophobicContact CG1-CG2 3.76Å; L452-I478 HydrophobicContact CB-CD1 3.87Å; L452-I478 HydrophobicContact CD2-CD1 3.44Å; L452-I478 VanDerWaalsContact CD2-CD1 3.44Å; L452-I478 HydrophobicContact CG-CD1 4.3Å; G474-I478 WeakPolarHBondContact O-CG1 3.49Å; G474-I478 PolarHBondContact O-N 2.92Å; G475-I478 PolarHBondContact O-N 2.93Å; I476-I478 PolarHBondContact O-N 3.17Å; I478-V480 PolarHBondContact O-N 3.2Å; I478-V481 PolarHBondContact O-N 2.7Å; I478-C482 WeakPolarHBondContact O-CB 3.25Å; I478-C482 PolarHBondContact O-N 3.39Å; I478-C482 PolarHBondContact O-SG 2.9Å
479	L	89.4	Confident	85.7	Confident	118 Å²	118	51.2 Å²	51.2	62%	0.618	29%	0.292	S	S	*	.	H	α-helix	trans	-60.6	-45.6	179.5	-175.7	154.1	0	0	0	111.4	G475 I476 V477 C482 A483	G475-L479 WeakPolarHBondContact O-CB 3.44Å; G475-L479 PolarHBondContact O-N 3.5Å; I476-L479 PolarHBondContact O-N 3.31Å; V477-L479 VanDerWaalsContact C-N 3.32Å; V477-L479 PolarHBondContact O-N 2.97Å; L479-C482 PolarHBondContact O-N 2.89Å; L479-A483 WeakPolarHBondContact O-CB 3.28Å; L479-A483 PolarHBondContact O-N 3.45Å
480	V	87.8	Confident	85.1	Confident	71 Å²	71	51.7 Å²	51.7	43%	0.43	28%	0.283	S	S	.	.	H	α-helix	trans	-61.8	-48	178.1	170.2	0	0	0	0	110.8	I476 V477 I478 C482 A483 I484	I476-V480 HydrophobicContact CG2-CG2 4.39Å; I476-V480 WeakPolarHBondContact O-CG2 3.31Å; I476-V480 PolarHBondContact O-N 3.28Å; V477-V480 PolarHBondContact O-N 3.31Å; I478-V480 PolarHBondContact O-N 3.2Å; V480-C482 PolarHBondContact O-N 3.02Å; V480-A483 PolarHBondContact O-N 3.43Å; V480-I484 HydrophobicContact CG1-CD1 3.74Å; V480-I484 HydrophobicContact CG1-CG1 4.48Å; V480-I484 VanDerWaalsContact O-CG1 3.31Å; V480-I484 WeakPolarHBondContact O-CG1 3.32Å; V480-I484 PolarHBondContact O-N 2.85Å
481	V	85.6	Confident	84.6	Confident	6 Å²	6	51.1 Å²	51.1	4%	0.036	29%	0.287	C	S	.	.	H	α-helix	trans	-61.2	-45.4	178.6	172.2	0	0	0	0	111	L444 P445 L448 V477 I478 A483 I484 N485	L444-V481 HydrophobicContact CB-CG1 3.7Å; L444-V481 HydrophobicContact CD1-CG1 4.03Å; P445-V481 HydrophobicContact CG-CG1 4.3Å; L448-V481 HydrophobicContact CD1-CB 4.22Å; L448-V481 HydrophobicContact CD1-CG1 4.06Å; L448-V481 HydrophobicContact CD1-CG2 3.88Å; V477-V481 HydrophobicContact CG1-CG2 4.39Å; V477-V481 VanDerWaalsContact O-CG2 3.26Å; V477-V481 WeakPolarHBondContact O-CG2 3.41Å; V477-V481 PolarHBondContact O-N 3.05Å; I478-V481 PolarHBondContact O-N 2.7Å; V481-A483 VanDerWaalsContact C-N 3.35Å; V481-A483 PolarHBondContact O-N 3.01Å; V481-I484 PolarHBondContact O-N 3.17Å; V481-N485 WeakPolarHBondContact O-CB 3.35Å; V481-N485 VanDerWaalsContact O-CG 3.32Å; V481-N485 PolarHBondContact O-N 3.4Å
482	C	84.8	Confident	83.8	Confident	32 Å²	32	53.8 Å²	53.8	22%	0.216	30%	0.297	C	S	.	.	H	α-helix	trans	-62.9	-39.6	176.5	-73	0	0	0	0	112.3	I478 L479 V480 N485 M486	I478-C482 WeakPolarHBondContact O-CB 3.25Å; I478-C482 PolarHBondContact O-N 3.39Å; I478-C482 PolarHBondContact O-SG 2.9Å; L479-C482 PolarHBondContact O-N 2.89Å; V480-C482 PolarHBondContact O-N 3.02Å; C482-N485 PolarHBondContact O-N 2.98Å; C482-M486 WeakPolarHBondContact O-CB 3.16Å; C482-M486 PolarHBondContact O-N 3.24Å
483	A	85.8	Confident	83	Confident	57 Å²	57	50 Å²	50	47%	0.471	28%	0.279	S	S	.	.	H	α-helix	trans	-65.4	-43.5	177.7	0	0	0	0	0	111.9	L479 V480 V481 M486 Y487	L479-A483 WeakPolarHBondContact O-CB 3.28Å; L479-A483 PolarHBondContact O-N 3.45Å; V480-A483 PolarHBondContact O-N 3.43Å; V481-A483 VanDerWaalsContact C-N 3.35Å; V481-A483 PolarHBondContact O-N 3.01Å; A483-M486 PolarHBondContact O-N 3.45Å; A483-Y487 PolarHBondContact O-N 2.79Å; A483-Y487 VanDerWaalsContact O-N 3.07Å
484	I	81.8	Confident	82.4	Confident	42 Å²	42	52.6 Å²	52.6	22%	0.215	29%	0.29	C	S	.	.	H	α-helix	trans	-61.3	-50.3	175.1	-71.7	168.4	0	0	0	110.3	V251 V480 V481 M486 Y487 F488	V251-I484 HydrophobicContact CB-CG2 4Å; V251-I484 HydrophobicContact CG1-CG2 3.26Å; V251-I484 HydrophobicContact CG2-CD1 4.37Å; V251-I484 HydrophobicContact CG2-CG1 4.42Å; V251-I484 HydrophobicContact CG2-CG2 3.51Å; V480-I484 HydrophobicContact CG1-CD1 3.74Å; V480-I484 HydrophobicContact CG1-CG1 4.48Å; V480-I484 VanDerWaalsContact O-CG1 3.31Å; V480-I484 WeakPolarHBondContact O-CG1 3.32Å; V480-I484 PolarHBondContact O-N 2.85Å; V481-I484 PolarHBondContact O-N 3.17Å; I484-M486 VanDerWaalsContact C-N 3.27Å; I484-M486 PolarHBondContact O-N 2.96Å; I484-Y487 WeakPolarHBondContact O-CB 3.24Å; I484-Y487 PolarHBondContact O-N 3.3Å; I484-Y487 VanDerWaalsContact O-N 3.1Å; I484-F488 HydrophobicContact CG2-CD2 4.11Å; I484-F488 HydrophobicContact CG2-CE2 4.23Å; I484-F488 WeakPolarHBondContact O-CD2 3.23Å; I484-F488 PolarHBondContact O-N 3.42Å; I484-F488 VanDerWaalsContact O-N 3.08Å
485	N	82.6	Confident	81.7	Confident	2 Å²	2	55.7 Å²	55.7	1%	0.011	31%	0.314	C	S	.	.	H	α-helix	trans	-61.3	-37.1	179	-74.3	-16.8	0	0	0	112.2	S441 L442 P445 V481 C482 Y487 F488 V489	S441-N485 PolarHBondContact O-ND2 2.91Å; S441-N485 PolarHBondContact O-OD1 3.25Å; S441-N485 PolarHBondContact OG-OD1 3.04Å; L442-N485 HydrophobicContact CD2-CB 3.96Å; P445-N485 WeakPolarHBondContact CD-ND2 2.95Å; V481-N485 WeakPolarHBondContact O-CB 3.35Å; V481-N485 VanDerWaalsContact O-CG 3.32Å; V481-N485 PolarHBondContact O-N 3.4Å; C482-N485 PolarHBondContact O-N 2.98Å; N485-Y487 VanDerWaalsContact C-N 3.35Å; N485-F488 PolarHBondContact O-N 2.78Å; N485-V489 WeakPolarHBondContact O-CG2 3.26Å; N485-V489 PolarHBondContact O-N 2.97Å
486	M	79.4	Confident	81.1	Confident	74 Å²	74	57.4 Å²	57.4	37%	0.365	32%	0.317	S	S	.	.	H	α-helix	trans	-62.9	-41.3	175.3	-173.6	62.7	-178.2	0	0	111.9	C482 A483 I484 V489 I490 L513	C482-M486 WeakPolarHBondContact O-CB 3.16Å; C482-M486 PolarHBondContact O-N 3.24Å; A483-M486 PolarHBondContact O-N 3.45Å; I484-M486 VanDerWaalsContact C-N 3.27Å; I484-M486 PolarHBondContact O-N 2.96Å; M486-V489 PolarHBondContact O-N 3.12Å; M486-I490 HydrophobicContact CE-CD1 4.24Å; M486-I490 HydrophobicContact CE-CG1 4.44Å; M486-I490 HydrophobicContact CG-CD1 4.32Å; M486-I490 WeakPolarHBondContact O-CG1 3.35Å; M486-I490 PolarHBondContact O-N 3.5Å; M486-I490 VanDerWaalsContact O-N 3.12Å; M486-L513 HydrophobicContact CE-CD1 3.6Å; M486-L513 HydrophobicContact SD-CD1 3.51Å; M486-L513 VanDerWaalsContact SD-CD1 3.51Å; M486-L513 HydrophobicContact SD-CD2 3.44Å; M486-L513 WeakPolarHBondContact SD-CD2 3.39Å; M486-L513 HydrophobicContact SD-CG 4.08Å
487	Y	81.4	Confident	80.4	Confident	126 Å²	126	61.1 Å²	61.1	49%	0.494	34%	0.338	S	S	.	.	H	α-helix	trans	-59.5	-46.9	174.3	173.5	-99.2	0	0	0	111.5	A483 I484 N485 V489 I490 V491	A483-Y487 PolarHBondContact O-N 2.79Å; A483-Y487 VanDerWaalsContact O-N 3.07Å; I484-Y487 WeakPolarHBondContact O-CB 3.24Å; I484-Y487 PolarHBondContact O-N 3.3Å; I484-Y487 VanDerWaalsContact O-N 3.1Å; N485-Y487 VanDerWaalsContact C-N 3.35Å; Y487-V489 PolarHBondContact O-N 3.31Å; Y487-I490 PolarHBondContact O-N 3.31Å; Y487-V491 HydrophobicContact CD1-CG2 4.22Å; Y487-V491 HydrophobicContact CD2-CG2 4.38Å; Y487-V491 HydrophobicContact CE1-CG2 3.78Å; Y487-V491 HydrophobicContact CE2-CG2 3.95Å; Y487-V491 WeakPolarHBondContact O-CG2 3.29Å; Y487-V491 PolarHBondContact O-N 3.36Å
488	F	73.4	Confident	80.1	Confident	14 Å²	14	62.2 Å²	62.2	6%	0.061	35%	0.347	C	S	.	.	H	α-helix	trans	-60.9	-45	177.9	-91.1	-88.3	0	0	0	113	E248 V251 V438 I484 N485 I490 V491 Y492	E248-F488 HydrophobicContact CG-CE1 4.24Å; E248-F488 HydrophobicContact CG-CZ 4.08Å; V251-F488 HydrophobicContact CB-CE2 3.64Å; V251-F488 HydrophobicContact CB-CZ 3.99Å; V251-F488 HydrophobicContact CG1-CD2 4.03Å; V251-F488 HydrophobicContact CG1-CE2 3.33Å; V251-F488 HydrophobicContact CG1-CZ 3.86Å; V251-F488 HydrophobicContact CG2-CE2 3.89Å; V438-F488 HydrophobicContact CG1-CD1 3.94Å; V438-F488 HydrophobicContact CG1-CE1 4.41Å; V438-F488 HydrophobicContact CG2-CE1 4.24Å; I484-F488 HydrophobicContact CG2-CD2 4.11Å; I484-F488 HydrophobicContact CG2-CE2 4.23Å; I484-F488 WeakPolarHBondContact O-CD2 3.23Å; I484-F488 PolarHBondContact O-N 3.42Å; I484-F488 VanDerWaalsContact O-N 3.08Å; N485-F488 PolarHBondContact O-N 2.78Å; F488-I490 VanDerWaalsContact C-N 3.27Å; F488-I490 PolarHBondContact O-N 3.34Å; F488-V491 PolarHBondContact O-N 3.31Å; F488-Y492 HydrophobicContact CD1-CD2 4.2Å; F488-Y492 AromaticContact CD1-CE2 3.89Å; F488-Y492 HydrophobicContact CD1-CE2 3.89Å; F488-Y492 HydrophobicContact CE1-CE2 4.47Å; F488-Y492 WeakPolarHBondContact O-CD2 3.49Å; F488-Y492 PolarHBondContact O-N 3.34Å
489	V	75.4	Confident	79.8	Confident	19 Å²	19	66.9 Å²	66.9	12%	0.115	38%	0.376	C	S	.	.	H	α-helix	trans	-56.1	-44.9	176	168.7	0	0	0	0	110.6	L442 N485 M486 Y487 V493 S509 Y512	L442-V489 HydrophobicContact CD2-CG2 3.87Å; N485-V489 WeakPolarHBondContact O-CG2 3.26Å; N485-V489 PolarHBondContact O-N 2.97Å; M486-V489 PolarHBondContact O-N 3.12Å; Y487-V489 PolarHBondContact O-N 3.31Å; V489-V493 HydrophobicContact CG1-CG2 4.32Å; V489-V493 VanDerWaalsContact O-CB 3.29Å; V489-V493 WeakPolarHBondContact O-CB 3.49Å; V489-V493 WeakPolarHBondContact O-CG2 3.16Å; V489-V493 PolarHBondContact O-N 3.28Å; V489-S509 WeakPolarHBondContact CG1-OG 3.43Å; V489-Y512 HydrophobicContact CG2-CE1 4.39Å
490	I	77.9	Confident	79.6	Confident	86 Å²	86	67 Å²	67	44%	0.441	38%	0.377	S	S	.	.	H	α-helix	trans	-62.4	-50.7	177.7	-66.4	165.4	0	0	0	110.6	M486 Y487 F488 Y492 V493 T494	M486-I490 HydrophobicContact CE-CD1 4.24Å; M486-I490 HydrophobicContact CE-CG1 4.44Å; M486-I490 HydrophobicContact CG-CD1 4.32Å; M486-I490 WeakPolarHBondContact O-CG1 3.35Å; M486-I490 PolarHBondContact O-N 3.5Å; M486-I490 VanDerWaalsContact O-N 3.12Å; Y487-I490 PolarHBondContact O-N 3.31Å; F488-I490 VanDerWaalsContact C-N 3.27Å; F488-I490 PolarHBondContact O-N 3.34Å; I490-Y492 PolarHBondContact O-N 3.16Å; I490-V493 PolarHBondContact O-N 2.91Å; I490-T494 HydrophobicContact CG2-CG2 4.3Å; I490-T494 WeakPolarHBondContact O-CB 3.31Å; I490-T494 VanDerWaalsContact O-CG2 3.29Å; I490-T494 WeakPolarHBondContact O-CG2 3.41Å; I490-T494 PolarHBondContact O-N 2.87Å; I490-T494 PolarHBondContact O-OG1 2.95Å; I490-T494 VanDerWaalsContact O-OG1 3.05Å
491	V	76.8	Confident	79.4	Confident	60 Å²	60	68.2 Å²	68.2	36%	0.364	38%	0.38	S	S	.	.	H	α-helix	trans	-57.1	-51	-178.5	172.3	0	0	0	0	110.9	Y487 F488 V493 T494 A495	Y487-V491 HydrophobicContact CD1-CG2 4.22Å; Y487-V491 HydrophobicContact CD2-CG2 4.38Å; Y487-V491 HydrophobicContact CE1-CG2 3.78Å; Y487-V491 HydrophobicContact CE2-CG2 3.95Å; Y487-V491 WeakPolarHBondContact O-CG2 3.29Å; Y487-V491 PolarHBondContact O-N 3.36Å; F488-V491 PolarHBondContact O-N 3.31Å; V491-V493 PolarHBondContact O-N 2.88Å; V491-T494 PolarHBondContact O-N 3.32Å; V491-T494 PolarHBondContact O-OG1 3.46Å; V491-A495 PolarHBondContact O-N 3.17Å; V491-A495 VanDerWaalsContact O-N 3.11Å
492	Y	71.6	Confident	79.3	Confident	98 Å²	98	73.1 Å²	73.1	38%	0.384	40%	0.399	S	S	.	.	H	α-helix	trans	-64.7	-41.8	-179.5	-90.1	-80.1	0	0	0	113	V438 F488 I490 T494 A495	V438-Y492 HydrophobicContact CG1-CE2 3.88Å; F488-Y492 HydrophobicContact CD1-CD2 4.2Å; F488-Y492 AromaticContact CD1-CE2 3.89Å; F488-Y492 HydrophobicContact CD1-CE2 3.89Å; F488-Y492 HydrophobicContact CE1-CE2 4.47Å; F488-Y492 WeakPolarHBondContact O-CD2 3.49Å; F488-Y492 PolarHBondContact O-N 3.34Å; I490-Y492 PolarHBondContact O-N 3.16Å; Y492-T494 VanDerWaalsContact C-N 3.32Å; Y492-T494 PolarHBondContact O-N 3.48Å; Y492-A495 PolarHBondContact O-N 3.03Å
493	V	73.8	Confident	79.3	Confident	17 Å²	17	75.2 Å²	75.2	10%	0.103	41%	0.41	C	S	.	.	H	α-helix	trans	-64.2	-39.7	177.7	170.9	0	0	0	0	110.7	V489 I490 V491 A495 L496 Y502 A505	V489-V493 HydrophobicContact CG1-CG2 4.32Å; V489-V493 VanDerWaalsContact O-CB 3.29Å; V489-V493 WeakPolarHBondContact O-CB 3.49Å; V489-V493 WeakPolarHBondContact O-CG2 3.16Å; V489-V493 PolarHBondContact O-N 3.28Å; I490-V493 PolarHBondContact O-N 2.91Å; V491-V493 PolarHBondContact O-N 2.88Å; V493-A495 VanDerWaalsContact C-N 3.29Å; V493-A495 PolarHBondContact O-N 3.17Å; V493-L496 PolarHBondContact O-N 3.13Å; V493-Y502 HydrophobicContact CG1-CD2 3.88Å; V493-Y502 HydrophobicContact CG1-CE2 3.57Å; V493-Y502 WeakPolarHBondContact O-CD2 3.49Å; V493-A505 HydrophobicContact CG2-CB 4.13Å
494	T	75.4	Confident	79.3	Confident	98 Å²	98	76.4 Å²	76.4	60%	0.601	41%	0.408	S	S	*	.	H	α-helix	trans	-70.9	-21.3	178	57.8	0	0	0	0	114.2	I490 V491 Y492 L496	I490-T494 HydrophobicContact CG2-CG2 4.3Å; I490-T494 WeakPolarHBondContact O-CB 3.31Å; I490-T494 VanDerWaalsContact O-CG2 3.29Å; I490-T494 WeakPolarHBondContact O-CG2 3.41Å; I490-T494 PolarHBondContact O-N 2.87Å; I490-T494 PolarHBondContact O-OG1 2.95Å; I490-T494 VanDerWaalsContact O-OG1 3.05Å; V491-T494 PolarHBondContact O-N 3.32Å; V491-T494 PolarHBondContact O-OG1 3.46Å; Y492-T494 VanDerWaalsContact C-N 3.32Å; Y492-T494 PolarHBondContact O-N 3.48Å; T494-L496 VanDerWaalsContact C-N 3.28Å; T494-L496 PolarHBondContact O-N 3.04Å
495	A	74.9	Confident	79.4	Confident	75 Å²	75	75.4 Å²	75.4	62%	0.62	41%	0.406	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.1	-9.9	177.3	0	0	0	0	0	113.7	V491 Y492 V493 N497	V491-A495 PolarHBondContact O-N 3.17Å; V491-A495 VanDerWaalsContact O-N 3.11Å; Y492-A495 PolarHBondContact O-N 3.03Å; V493-A495 VanDerWaalsContact C-N 3.29Å; V493-A495 PolarHBondContact O-N 3.17Å; A495-N497 PolarHBondContact O-N 3.02Å
496	L	76.2	Confident	79.5	Confident	61 Å²	61	76.8 Å²	76.8	32%	0.319	42%	0.418	S	S	.	.			trans	-75.9	111	-178.3	-66.2	171.1	0	0	0	111.4	V493 T494 S498 L501 A505	V493-L496 PolarHBondContact O-N 3.13Å; T494-L496 VanDerWaalsContact C-N 3.28Å; T494-L496 PolarHBondContact O-N 3.04Å; L496-S498 PolarHBondContact O-N 3.41Å; L496-L501 HydrophobicContact CD1-CB 4.37Å; L496-L501 HydrophobicContact CD2-CB 4.38Å; L496-A505 HydrophobicContact CD1-CB 3.33Å
497	N	75.2	Confident	79.8	Confident	180 Å²	180	78.9 Å²	78.9	96%	0.963	43%	0.43	S	S	*	.			trans	-77.4	2.5	-177.4	-119.4	3.2	0	0	0	114.7	A495	A495-N497 PolarHBondContact O-N 3.02Å
498	S	84	Confident	80.1	Confident	52 Å²	52	78.2 Å²	78.2	36%	0.364	43%	0.434	S	S	.	.			trans	-121.7	128.3	-178.3	173.5	0	0	0	0	111.2	L496 L500 L501 Y502	L496-S498 PolarHBondContact O-N 3.41Å; S498-L500 VanDerWaalsContact C-N 3.28Å; S498-L500 PolarHBondContact O-N 3.33Å; S498-L501 PolarHBondContact O-N 2.88Å; S498-Y502 WeakPolarHBondContact O-CB 3.42Å; S498-Y502 PolarHBondContact O-N 3.25Å
499	V	83	Confident	80.7	Confident	117 Å²	117	78.5 Å²	78.5	71%	0.709	44%	0.438	S	S	*	.	H	α-helix	trans	-58.7	-38.3	-178.7	-178.7	0	0	0	0	111.9	Y502 V503	V499-Y502 WeakPolarHBondContact O-CB 3.29Å; V499-Y502 PolarHBondContact O-N 3.34Å; V499-V503 WeakPolarHBondContact O-CG2 3.5Å; V499-V503 PolarHBondContact O-N 3.09Å
500	L	85.5	Confident	81.2	Confident	120 Å²	120	81.9 Å²	81.9	63%	0.628	46%	0.458	S	S	*	.	H	α-helix	trans	-66.7	-46.5	178.7	179.9	64.1	0	0	0	111.5	S498 Y502 V503 I504	S498-L500 VanDerWaalsContact C-N 3.28Å; S498-L500 PolarHBondContact O-N 3.33Å; L500-Y502 VanDerWaalsContact C-N 3.29Å; L500-Y502 PolarHBondContact O-N 2.88Å; L500-V503 PolarHBondContact O-N 3.46Å; L500-I504 HydrophobicContact CD1-CD1 4.16Å; L500-I504 HydrophobicContact CG-CD1 4.06Å; L500-I504 WeakPolarHBondContact O-CG1 3.4Å; L500-I504 PolarHBondContact O-N 3.44Å
501	L	81.9	Confident	81.8	Confident	96 Å²	96	80.7 Å²	80.7	50%	0.503	46%	0.461	S	S	.	.	H	α-helix	trans	-63.9	-38.4	176.9	-68.4	178.4	0	0	0	111	L496 S498 I504 A505	L496-L501 HydrophobicContact CD1-CB 4.37Å; L496-L501 HydrophobicContact CD2-CB 4.38Å; S498-L501 PolarHBondContact O-N 2.88Å; L501-I504 PolarHBondContact O-N 3.42Å; L501-A505 WeakPolarHBondContact O-CB 3.35Å; L501-A505 PolarHBondContact O-N 3.2Å
502	Y	83.9	Confident	82.4	Confident	110 Å²	110	79 Å²	79	43%	0.431	45%	0.449	S	S	.	.	H	α-helix	trans	-59.8	-47.9	175.2	-176.7	-89.2	0	0	0	111.9	V493 S498 V499 L500 A505 A506	V493-Y502 HydrophobicContact CG1-CD2 3.88Å; V493-Y502 HydrophobicContact CG1-CE2 3.57Å; V493-Y502 WeakPolarHBondContact O-CD2 3.49Å; S498-Y502 WeakPolarHBondContact O-CB 3.42Å; S498-Y502 PolarHBondContact O-N 3.25Å; V499-Y502 WeakPolarHBondContact O-CB 3.29Å; V499-Y502 PolarHBondContact O-N 3.34Å; L500-Y502 VanDerWaalsContact C-N 3.29Å; L500-Y502 PolarHBondContact O-N 2.88Å; Y502-A505 PolarHBondContact O-N 2.92Å; Y502-A506 VanDerWaalsContact O-CB 3.23Å; Y502-A506 WeakPolarHBondContact O-CB 3.26Å; Y502-A506 PolarHBondContact O-N 2.89Å
503	V	85.6	Confident	83.2	Confident	75 Å²	75	76.3 Å²	76.3	46%	0.455	44%	0.441	S	S	.	.	H	α-helix	trans	-62.7	-44.8	178.4	171.8	0	0	0	0	111.3	V499 L500 A506 L507	V499-V503 WeakPolarHBondContact O-CG2 3.5Å; V499-V503 PolarHBondContact O-N 3.09Å; L500-V503 PolarHBondContact O-N 3.46Å; V503-A506 PolarHBondContact O-N 3.24Å; V503-L507 HydrophobicContact CG1-CD1 4.22Å; V503-L507 WeakPolarHBondContact O-CG 3.5Å; V503-L507 PolarHBondContact O-N 3.15Å
504	I	86.4	Confident	84	Confident	82 Å²	82	79.8 Å²	79.8	42%	0.421	46%	0.461	S	S	.	.	H	α-helix	trans	-63	-48.2	178.4	-67.2	168.8	0	0	0	110.6	L500 L501 A506 L507 I508	L500-I504 HydrophobicContact CD1-CD1 4.16Å; L500-I504 HydrophobicContact CG-CD1 4.06Å; L500-I504 WeakPolarHBondContact O-CG1 3.4Å; L500-I504 PolarHBondContact O-N 3.44Å; L501-I504 PolarHBondContact O-N 3.42Å; I504-A506 VanDerWaalsContact C-N 3.32Å; I504-A506 PolarHBondContact O-N 3.11Å; I504-L507 PolarHBondContact O-N 3.23Å; I504-I508 HydrophobicContact CG2-CD1 3.88Å; I504-I508 WeakPolarHBondContact O-CG1 3.19Å; I504-I508 PolarHBondContact O-N 3.36Å
505	A	83.6	Confident	84.8	Confident	22 Å²	22	76 Å²	76	18%	0.182	44%	0.437	C	S	.	.	H	α-helix	trans	-63.6	-38.3	179.6	0	0	0	0	0	112	V493 L496 L501 Y502 I508 S509	V493-A505 HydrophobicContact CG2-CB 4.13Å; L496-A505 HydrophobicContact CD1-CB 3.33Å; L501-A505 WeakPolarHBondContact O-CB 3.35Å; L501-A505 PolarHBondContact O-N 3.2Å; Y502-A505 PolarHBondContact O-N 2.92Å; A505-I508 PolarHBondContact O-N 3.07Å; A505-S509 VanDerWaalsContact O-CB 3.28Å; A505-S509 WeakPolarHBondContact O-CB 3.14Å; A505-S509 PolarHBondContact O-N 2.98Å; A505-S509 PolarHBondContact O-OG 2.92Å
506	A	83.3	Confident	85.6	Confident	31 Å²	31	73.1 Å²	73.1	26%	0.256	41%	0.411	S	S	.	.	H	α-helix	trans	-63.1	-44	174.6	0	0	0	0	0	111.7	Y502 V503 I504 S509 V510	Y502-A506 VanDerWaalsContact O-CB 3.23Å; Y502-A506 WeakPolarHBondContact O-CB 3.26Å; Y502-A506 PolarHBondContact O-N 2.89Å; V503-A506 PolarHBondContact O-N 3.24Å; I504-A506 VanDerWaalsContact C-N 3.32Å; I504-A506 PolarHBondContact O-N 3.11Å; A506-S509 PolarHBondContact O-N 3.47Å; A506-V510 VanDerWaalsContact O-CG2 3.31Å; A506-V510 WeakPolarHBondContact O-CG2 3.43Å; A506-V510 PolarHBondContact O-N 3.35Å
507	L	87.6	Confident	86.2	Confident	118 Å²	118	75.6 Å²	75.6	62%	0.618	42%	0.423	S	S	*	.	H	α-helix	trans	-62	-44.9	176.6	-73	171.6	0	0	0	112.2	V503 I504 S509 V510 A511	V503-L507 HydrophobicContact CG1-CD1 4.22Å; V503-L507 WeakPolarHBondContact O-CG 3.5Å; V503-L507 PolarHBondContact O-N 3.15Å; I504-L507 PolarHBondContact O-N 3.23Å; L507-S509 VanDerWaalsContact C-N 3.33Å; L507-S509 PolarHBondContact O-N 3.44Å; L507-V510 PolarHBondContact O-N 3.21Å; L507-A511 PolarHBondContact O-N 3.12Å
508	I	87.1	Confident	86.9	Confident	111 Å²	111	70.5 Å²	70.5	57%	0.569	39%	0.391	S	S	*	.	H	α-helix	trans	-61.8	-44.1	176.3	-67.4	169.3	0	0	0	110.5	I504 A505 V510 A511 Y512	I504-I508 HydrophobicContact CG2-CD1 3.88Å; I504-I508 WeakPolarHBondContact O-CG1 3.19Å; I504-I508 PolarHBondContact O-N 3.36Å; A505-I508 PolarHBondContact O-N 3.07Å; I508-V510 PolarHBondContact O-N 3.37Å; I508-A511 PolarHBondContact O-N 3.23Å; I508-Y512 WeakPolarHBondContact O-CB 3.45Å; I508-Y512 PolarHBondContact O-N 3.27Å
509	S	84.6	Confident	87.2	Confident	21 Å²	21	68 Å²	68	15%	0.147	37%	0.374	C	S	.	.	H	α-helix	trans	-62.3	-43.5	179	-60.4	0	0	0	0	111.7	V489 A505 A506 L507 Y512 L513	V489-S509 WeakPolarHBondContact CG1-OG 3.43Å; A505-S509 VanDerWaalsContact O-CB 3.28Å; A505-S509 WeakPolarHBondContact O-CB 3.14Å; A505-S509 PolarHBondContact O-N 2.98Å; A505-S509 PolarHBondContact O-OG 2.92Å; A506-S509 PolarHBondContact O-N 3.47Å; L507-S509 VanDerWaalsContact C-N 3.33Å; L507-S509 PolarHBondContact O-N 3.44Å; S509-Y512 PolarHBondContact O-N 3.47Å; S509-L513 WeakPolarHBondContact O-CB 3.07Å; S509-L513 VanDerWaalsContact O-CG 3.25Å; S509-L513 WeakPolarHBondContact O-CG 3.43Å; S509-L513 PolarHBondContact O-N 3.49Å
510	V	87.3	Confident	87.4	Confident	89 Å²	89	63.9 Å²	63.9	54%	0.539	35%	0.351	S	S	.	.	H	α-helix	trans	-62.7	-45.1	175.4	171	0	0	0	0	110.7	A506 L507 I508 Y512 L513 V514	A506-V510 VanDerWaalsContact O-CG2 3.31Å; A506-V510 WeakPolarHBondContact O-CG2 3.43Å; A506-V510 PolarHBondContact O-N 3.35Å; L507-V510 PolarHBondContact O-N 3.21Å; I508-V510 PolarHBondContact O-N 3.37Å; V510-Y512 PolarHBondContact O-N 2.99Å; V510-L513 PolarHBondContact O-N 3.34Å; V510-V514 HydrophobicContact CG1-CG2 4.29Å; V510-V514 WeakPolarHBondContact O-CB 3.33Å; V510-V514 VanDerWaalsContact O-CG2 3.25Å; V510-V514 WeakPolarHBondContact O-CG2 3.29Å; V510-V514 PolarHBondContact O-N 3.44Å
511	A	90.1	Very high	87.5	Confident	62 Å²	62	63.4 Å²	63.4	51%	0.512	34%	0.341	S	S	.	.	H	α-helix	trans	-60.8	-43.9	177.3	0	0	0	0	0	112.2	L507 I508 V514 F515	L507-A511 PolarHBondContact O-N 3.12Å; I508-A511 PolarHBondContact O-N 3.23Å; A511-V514 PolarHBondContact O-N 3.42Å; A511-F515 PolarHBondContact O-N 3.43Å
512	Y	89.8	Confident	87.6	Confident	25 Å²	25	62.4 Å²	62.4	10%	0.098	33%	0.334	C	S	.	.	H	α-helix	trans	-59	-48	174.8	167.6	-93.9	0	0	0	111.9	L442 F446 V489 I508 S509 V510 F515 I516	L442-Y512 WeakPolarHBondContact O-CE2 3.47Å; L442-Y512 PolarHBondContact O-OH 3.41Å; F446-Y512 AromaticContact CE2-CD2 3.94Å; F446-Y512 HydrophobicContact CE2-CD2 3.94Å; F446-Y512 AromaticContact CE2-CE2 3.53Å; F446-Y512 HydrophobicContact CE2-CE2 3.53Å; F446-Y512 AromaticContact CZ-CD2 3.63Å; F446-Y512 HydrophobicContact CZ-CD2 3.63Å; F446-Y512 AromaticContact CZ-CE2 3.53Å; F446-Y512 HydrophobicContact CZ-CE2 3.53Å; V489-Y512 HydrophobicContact CG2-CE1 4.39Å; I508-Y512 WeakPolarHBondContact O-CB 3.45Å; I508-Y512 PolarHBondContact O-N 3.27Å; S509-Y512 PolarHBondContact O-N 3.47Å; V510-Y512 PolarHBondContact O-N 2.99Å; Y512-F515 PolarHBondContact O-N 2.86Å; Y512-I516 HydrophobicContact CD1-CD1 4.09Å; Y512-I516 HydrophobicContact CD2-CD1 4.39Å; Y512-I516 HydrophobicContact CE1-CD1 3.4Å; Y512-I516 VanDerWaalsContact CE1-CD1 3.4Å; Y512-I516 HydrophobicContact CE2-CD1 3.75Å; Y512-I516 PolarHBondContact O-N 2.99Å; Y512-I516 VanDerWaalsContact OH-CD1 3.28Å; Y512-I516 WeakPolarHBondContact OH-CD1 3.2Å
513	L	88.1	Confident	87.7	Confident	41 Å²	41	57.5 Å²	57.5	22%	0.215	32%	0.315	C	S	.	.	H	α-helix	trans	-66.1	-41.2	179.6	-68.7	171.5	0	0	0	112.5	M486 S509 V510 F515 I516 I517	M486-L513 HydrophobicContact CE-CD1 3.6Å; M486-L513 HydrophobicContact SD-CD1 3.51Å; M486-L513 VanDerWaalsContact SD-CD1 3.51Å; M486-L513 HydrophobicContact SD-CD2 3.44Å; M486-L513 WeakPolarHBondContact SD-CD2 3.39Å; M486-L513 HydrophobicContact SD-CG 4.08Å; S509-L513 WeakPolarHBondContact O-CB 3.07Å; S509-L513 VanDerWaalsContact O-CG 3.25Å; S509-L513 WeakPolarHBondContact O-CG 3.43Å; S509-L513 PolarHBondContact O-N 3.49Å; V510-L513 PolarHBondContact O-N 3.34Å; L513-F515 VanDerWaalsContact C-N 3.27Å; L513-F515 PolarHBondContact O-N 3.42Å; L513-I516 PolarHBondContact O-N 3.46Å; L513-I517 WeakPolarHBondContact O-CB 3.23Å; L513-I517 WeakPolarHBondContact O-CD1 3.5Å; L513-I517 WeakPolarHBondContact O-CG1 3.36Å; L513-I517 PolarHBondContact O-N 2.87Å
514	V	90.9	Very high	87.7	Confident	89 Å²	89	57.2 Å²	57.2	54%	0.539	31%	0.311	S	S	.	.	H	α-helix	trans	-59.1	-42.3	175	168.2	0	0	0	0	110.4	V510 A511 I517 Y518	V510-V514 HydrophobicContact CG1-CG2 4.29Å; V510-V514 WeakPolarHBondContact O-CB 3.33Å; V510-V514 VanDerWaalsContact O-CG2 3.25Å; V510-V514 WeakPolarHBondContact O-CG2 3.29Å; V510-V514 PolarHBondContact O-N 3.44Å; A511-V514 PolarHBondContact O-N 3.42Å; V514-I517 PolarHBondContact O-N 3.2Å; V514-Y518 WeakPolarHBondContact O-CB 3.34Å; V514-Y518 PolarHBondContact O-N 2.79Å
515	F	92.5	Very high	87.4	Confident	20 Å²	20	56 Å²	56	9%	0.088	31%	0.308	C	S	.	.	H	α-helix	trans	-67.6	-40.5	178.6	-172.6	-135.4	0	0	0	112.5	P139 L142 L143 F446 A511 Y512 L513 Y518 L519	P139-F515 HydrophobicContact CB-CE2 4.1Å; L142-F515 HydrophobicContact CB-CE1 3.99Å; L142-F515 HydrophobicContact CB-CE2 4.2Å; L142-F515 HydrophobicContact CB-CZ 3.77Å; L142-F515 HydrophobicContact CD1-CD2 4.43Å; L142-F515 HydrophobicContact CD1-CE2 4.41Å; L143-F515 HydrophobicContact CB-CZ 4.12Å; L143-F515 HydrophobicContact CD1-CE1 4.48Å; F446-F515 HydrophobicContact CD1-CD1 4.02Å; F446-F515 AromaticContact CD1-CE1 3.81Å; F446-F515 HydrophobicContact CD1-CE1 3.81Å; F446-F515 AromaticContact CE1-CD1 3.28Å; F446-F515 HydrophobicContact CE1-CD1 3.28Å; F446-F515 AromaticContact CE1-CE1 3.55Å; F446-F515 HydrophobicContact CE1-CE1 3.55Å; F446-F515 HydrophobicContact CE1-CG 4.3Å; F446-F515 AromaticContact CZ-CD1 3.92Å; F446-F515 HydrophobicContact CZ-CD1 3.92Å; F446-F515 HydrophobicContact CZ-CE1 4.39Å; A511-F515 PolarHBondContact O-N 3.43Å; Y512-F515 PolarHBondContact O-N 2.86Å; L513-F515 VanDerWaalsContact C-N 3.27Å; L513-F515 PolarHBondContact O-N 3.42Å; F515-Y518 HydrophobicContact CD2-CD1 4.3Å; F515-Y518 HydrophobicContact CE2-CD1 4.3Å; F515-Y518 WeakPolarHBondContact O-CB 3.13Å; F515-Y518 PolarHBondContact O-N 3.06Å; F515-L519 HydrophobicContact CE1-CD1 4.14Å; F515-L519 HydrophobicContact CE2-CD1 4.33Å; F515-L519 HydrophobicContact CE2-CD2 4.32Å; F515-L519 HydrophobicContact CE2-CG 4.21Å; F515-L519 HydrophobicContact CZ-CD1 4.02Å; F515-L519 HydrophobicContact CZ-CD2 4.47Å; F515-L519 HydrophobicContact CZ-CG 4.37Å; F515-L519 WeakPolarHBondContact O-CG 3.32Å; F515-L519 PolarHBondContact O-N 3.33Å
516	I	90.2	Very high	87.1	Confident	14 Å²	14	55.7 Å²	55.7	7%	0.072	31%	0.305	C	S	.	.	H	α-helix	trans	-62.3	-45	172.9	-73.3	-178.9	0	0	0	111.4	P445 F446 I449 Y512 L513 Y518 L519 A520	P445-I516 HydrophobicContact CB-CD1 3.83Å; P445-I516 HydrophobicContact CB-CG1 4.17Å; P445-I516 HydrophobicContact CG-CD1 3.84Å; F446-I516 HydrophobicContact CE1-CG1 3.87Å; F446-I516 HydrophobicContact CZ-CD1 4.44Å; F446-I516 HydrophobicContact CZ-CG1 4.07Å; I449-I516 HydrophobicContact CD1-CG2 4.21Å; Y512-I516 HydrophobicContact CD1-CD1 4.09Å; Y512-I516 HydrophobicContact CD2-CD1 4.39Å; Y512-I516 HydrophobicContact CE1-CD1 3.4Å; Y512-I516 VanDerWaalsContact CE1-CD1 3.4Å; Y512-I516 HydrophobicContact CE2-CD1 3.75Å; Y512-I516 PolarHBondContact O-N 2.99Å; Y512-I516 VanDerWaalsContact OH-CD1 3.28Å; Y512-I516 WeakPolarHBondContact OH-CD1 3.2Å; L513-I516 PolarHBondContact O-N 3.46Å; I516-Y518 VanDerWaalsContact C-N 3.28Å; I516-Y518 PolarHBondContact O-N 3.42Å; I516-L519 PolarHBondContact O-N 3.3Å; I516-A520 VanDerWaalsContact O-CB 3.25Å; I516-A520 WeakPolarHBondContact O-CB 3.04Å; I516-A520 PolarHBondContact O-N 3.05Å
517	I	89.9	Confident	86.9	Confident	112 Å²	112	56 Å²	56	57%	0.574	30%	0.302	S	S	*	.	H	α-helix	trans	-60.6	-41.4	178.2	-70.6	164.7	0	0	0	110.2	L513 V514 A520 W521	L513-I517 WeakPolarHBondContact O-CB 3.23Å; L513-I517 WeakPolarHBondContact O-CD1 3.5Å; L513-I517 WeakPolarHBondContact O-CG1 3.36Å; L513-I517 PolarHBondContact O-N 2.87Å; V514-I517 PolarHBondContact O-N 3.2Å; I517-A520 PolarHBondContact O-N 3.24Å; I517-W521 VanDerWaalsContact O-CB 3.28Å; I517-W521 WeakPolarHBondContact O-CB 3.42Å; I517-W521 PolarHBondContact O-N 3.28Å
518	Y	90.4	Very high	86.2	Confident	74 Å²	74	52.9 Å²	52.9	29%	0.29	30%	0.298	S	S	.	.	H	α-helix	trans	-59	-49.1	174.6	171	-96.9	0	0	0	112.2	P139 V514 F515 I516 W521 H522	P139-Y518 HydrophobicContact CB-CE1 3.73Å; P139-Y518 HydrophobicContact CG-CD1 4.49Å; P139-Y518 HydrophobicContact CG-CE1 3.6Å; V514-Y518 WeakPolarHBondContact O-CB 3.34Å; V514-Y518 PolarHBondContact O-N 2.79Å; F515-Y518 HydrophobicContact CD2-CD1 4.3Å; F515-Y518 HydrophobicContact CE2-CD1 4.3Å; F515-Y518 WeakPolarHBondContact O-CB 3.13Å; F515-Y518 PolarHBondContact O-N 3.06Å; I516-Y518 VanDerWaalsContact C-N 3.28Å; I516-Y518 PolarHBondContact O-N 3.42Å; Y518-W521 WeakPolarHBondContact O-CB 3.22Å; Y518-W521 PolarHBondContact O-N 3.4Å; Y518-H522 AromaticContact CE1-CD2 3.92Å; Y518-H522 AromaticContact CE2-CD2 3.63Å; Y518-H522 AromaticContact CE2-NE2 3.38Å; Y518-H522 WeakPolarHBondContact CE2-NE2 2.98Å; Y518-H522 AromaticContact CZ-CD2 3.5Å; Y518-H522 AromaticContact CZ-NE2 3.3Å; Y518-H522 VanDerWaalsContact CZ-NE2 3.3Å; Y518-H522 PolarHBondContact O-CD2 2.96Å; Y518-H522 PolarHBondContact O-N 3.03Å; Y518-H522 PolarHBondContact OH-NE2 3.48Å; Y518-H522 VanDerWaalsContact OH-NE2 3.11Å
519	L	89.5	Confident	85.6	Confident	0 Å²	0	50.2 Å²	50.2	0%	0	29%	0.287	C	S	.	.	H	α-helix	trans	-65.5	-42.3	178	-65.9	176.4	0	0	0	111.8	Y135 L143 F446 I449 F515 I516 W521 H522 C523	Y135-L519 HydrophobicContact CE1-CD2 4Å; Y135-L519 HydrophobicContact CE2-CD2 4.4Å; L143-L519 HydrophobicContact CD1-CD1 4.26Å; F446-L519 HydrophobicContact CD1-CD1 3.74Å; F446-L519 HydrophobicContact CE1-CD1 4.21Å; I449-L519 HydrophobicContact CB-CB 4.4Å; I449-L519 HydrophobicContact CD1-CB 4.21Å; I449-L519 HydrophobicContact CG2-CB 3.82Å; I449-L519 WeakPolarHBondContact CG2-O 3.36Å; F515-L519 HydrophobicContact CE1-CD1 4.14Å; F515-L519 HydrophobicContact CE2-CD1 4.33Å; F515-L519 HydrophobicContact CE2-CD2 4.32Å; F515-L519 HydrophobicContact CE2-CG 4.21Å; F515-L519 HydrophobicContact CZ-CD1 4.02Å; F515-L519 HydrophobicContact CZ-CD2 4.47Å; F515-L519 HydrophobicContact CZ-CG 4.37Å; F515-L519 WeakPolarHBondContact O-CG 3.32Å; F515-L519 PolarHBondContact O-N 3.33Å; I516-L519 PolarHBondContact O-N 3.3Å; L519-W521 VanDerWaalsContact C-N 3.31Å; L519-W521 PolarHBondContact O-N 3.48Å; L519-H522 PolarHBondContact O-N 3.31Å; L519-C523 PolarHBondContact O-N 3.27Å
520	A	88.1	Confident	84.1	Confident	29 Å²	29	54.3 Å²	54.3	24%	0.24	32%	0.315	C	S	.	.	H	α-helix	trans	-63.8	-37.9	178.5	0	0	0	0	0	111.6	I449 I516 I517 C523 L524	I449-A520 HydrophobicContact CD1-CB 4.45Å; I516-A520 VanDerWaalsContact O-CB 3.25Å; I516-A520 WeakPolarHBondContact O-CB 3.04Å; I516-A520 PolarHBondContact O-N 3.05Å; I517-A520 PolarHBondContact O-N 3.24Å; A520-C523 WeakPolarHBondContact O-CB 3.36Å; A520-C523 PolarHBondContact O-N 3.4Å; A520-L524 WeakPolarHBondContact O-CG 3.37Å; A520-L524 PolarHBondContact O-N 2.01Å
521	W	87.3	Confident	82.5	Confident	111 Å²	111	54.6 Å²	54.6	42%	0.42	32%	0.32	S	S	.	.	H	α-helix	trans	-58.6	-50.6	173	176.5	-93	0	0	0	111.6	I517 Y518 L519 C523 L524 V525 L532	I517-W521 VanDerWaalsContact O-CB 3.28Å; I517-W521 WeakPolarHBondContact O-CB 3.42Å; I517-W521 PolarHBondContact O-N 3.28Å; Y518-W521 WeakPolarHBondContact O-CB 3.22Å; Y518-W521 PolarHBondContact O-N 3.4Å; L519-W521 VanDerWaalsContact C-N 3.31Å; L519-W521 PolarHBondContact O-N 3.48Å; W521-C523 VanDerWaalsContact C-N 3.27Å; W521-C523 PolarHBondContact O-N 3.18Å; W521-L524 PolarHBondContact O-N 3.4Å; W521-L524 VanDerWaalsContact O-N 3.15Å; W521-V525 WeakPolarHBondContact O-CG2 3.33Å; W521-V525 PolarHBondContact O-N 3.17Å; W521-L532 HydrophobicContact CE3-CB 4.48Å; W521-L532 HydrophobicContact CE3-CD2 4.22Å; W521-L532 HydrophobicContact CH2-CB 3.58Å; W521-L532 HydrophobicContact CH2-CD2 3.71Å; W521-L532 HydrophobicContact CH2-CG 4.17Å; W521-L532 WeakPolarHBondContact CH2-O 3.29Å; W521-L532 HydrophobicContact CZ2-CB 4.04Å; W521-L532 WeakPolarHBondContact CZ2-O 3.5Å; W521-L532 HydrophobicContact CZ3-CB 3.85Å; W521-L532 HydrophobicContact CZ3-CD1 4.33Å; W521-L532 HydrophobicContact CZ3-CD2 3.31Å; W521-L532 HydrophobicContact CZ3-CG 3.98Å
522	H	83.9	Confident	80.8	Confident	74 Å²	74	53.9 Å²	53.9	34%	0.343	31%	0.308	S	S	.	.	H	α-helix	trans	-58.5	-39.3	174.7	-86.6	-82.5	0	0	0	112.3	Y518 L519 V525 A526	Y518-H522 AromaticContact CE1-CD2 3.92Å; Y518-H522 AromaticContact CE2-CD2 3.63Å; Y518-H522 AromaticContact CE2-NE2 3.38Å; Y518-H522 WeakPolarHBondContact CE2-NE2 2.98Å; Y518-H522 AromaticContact CZ-CD2 3.5Å; Y518-H522 AromaticContact CZ-NE2 3.3Å; Y518-H522 VanDerWaalsContact CZ-NE2 3.3Å; Y518-H522 PolarHBondContact O-CD2 2.96Å; Y518-H522 PolarHBondContact O-N 3.03Å; Y518-H522 PolarHBondContact OH-NE2 3.48Å; Y518-H522 VanDerWaalsContact OH-NE2 3.11Å; L519-H522 PolarHBondContact O-N 3.31Å; H522-V525 PolarHBondContact O-N 3.38Å; H522-A526 PolarHBondContact O-N 3.34Å
523	C	85.8	Confident	79	Confident	7 Å²	7	56.7 Å²	56.7	5%	0.047	32%	0.324	C	S	.	.	H	α-helix	trans	-63.4	-44.1	174.9	-172.7	0	0	0	0	112.3	I449 T453 L519 A520 W521 V525 A526 L527	I449-C523 HydrophobicContact CG2-CB 3.71Å; T453-C523 WeakPolarHBondContact OG1-CA 3.37Å; T453-C523 WeakPolarHBondContact OG1-CB 3.39Å; T453-C523 PolarHBondContact OG1-SG 3.32Å; T453-C523 VanDerWaalsContact OG1-SG 3.39Å; L519-C523 PolarHBondContact O-N 3.27Å; A520-C523 WeakPolarHBondContact O-CB 3.36Å; A520-C523 PolarHBondContact O-N 3.4Å; W521-C523 VanDerWaalsContact C-N 3.27Å; W521-C523 PolarHBondContact O-N 3.18Å; C523-V525 VanDerWaalsContact C-N 3.32Å; C523-V525 PolarHBondContact O-N 3.29Å; C523-A526 CarbonylContact O-C 3.59Å; C523-A526 WeakPolarHBondContact O-CB 3.28Å; C523-A526 PolarHBondContact O-N 3.36Å; C523-L527 WeakPolarHBondContact O-CG 3.15Å; C523-L527 PolarHBondContact O-N 3.26Å
524	L	84.6	Confident	76.8	Confident	69 Å²	69	58.4 Å²	58.4	36%	0.361	34%	0.339	S	S	.	.	H	α-helix	trans	-63.8	-37.9	179.2	-72.7	169.8	0	0	0	112.1	A520 W521 L527 G528 V529 L532	A520-L524 WeakPolarHBondContact O-CG 3.37Å; A520-L524 PolarHBondContact O-N 2.01Å; W521-L524 PolarHBondContact O-N 3.4Å; W521-L524 VanDerWaalsContact O-N 3.15Å; L524-L527 HydrophobicContact CD2-CD1 4.43Å; L524-L527 PolarHBondContact O-N 3.01Å; L524-G528 PolarHBondContact O-N 3.41Å; L524-V529 HydrophobicContact CD2-CG2 4.33Å; L524-V529 PolarHBondContact O-N 3.31Å; L524-L532 HydrophobicContact CB-CD1 3.84Å; L524-L532 HydrophobicContact CD1-CD1 3.8Å; L524-L532 HydrophobicContact CG-CD1 4.38Å
525	V	81.9	Confident	74.6	Confident	58 Å²	58	57.4 Å²	57.4	35%	0.352	35%	0.346	S	S	.	.	H	α-helix	trans	-61.5	-47.4	172.1	174.8	0	0	0	0	110.3	W521 H522 C523 L527 G528	W521-V525 WeakPolarHBondContact O-CG2 3.33Å; W521-V525 PolarHBondContact O-N 3.17Å; H522-V525 PolarHBondContact O-N 3.38Å; C523-V525 VanDerWaalsContact C-N 3.32Å; C523-V525 PolarHBondContact O-N 3.29Å; V525-L527 VanDerWaalsContact C-N 3.25Å; V525-L527 PolarHBondContact O-N 2.76Å; V525-G528 PolarHBondContact O-N 3.29Å
526	A	76.6	Confident	72	Confident	15 Å²	15	59.7 Å²	59.7	12%	0.124	37%	0.365	C	S	.	.	H	α-helix	trans	-63.8	-27.4	176.5	0	0	0	0	0	114	T453 L457 H522 C523 G528	T453-A526 HydrophobicContact CG2-CB 3.7Å; L457-A526 HydrophobicContact CD1-CB 4.35Å; L457-A526 HydrophobicContact CD2-CB 3.66Å; L457-A526 HydrophobicContact CG-CB 3.83Å; H522-A526 PolarHBondContact O-N 3.34Å; C523-A526 CarbonylContact O-C 3.59Å; C523-A526 WeakPolarHBondContact O-CB 3.28Å; C523-A526 PolarHBondContact O-N 3.36Å; A526-G528 PolarHBondContact O-N 2.78Å
527	L	78.9	Confident	69.4	Low	38 Å²	38	69.8 Å²	69.8	20%	0.199	40%	0.402	C	S	.	.	T	Hydrogen-bonded Turn	trans	-76	-10	174.8	-68.3	166.7	0	0	0	112.7	K471 C523 L524 V525	K471-L527 HydrophobicContact CB-CD2 3.59Å; K471-L527 HydrophobicContact CD-CD2 3.97Å; K471-L527 HydrophobicContact CG-CD2 3.69Å; C523-L527 WeakPolarHBondContact O-CG 3.15Å; C523-L527 PolarHBondContact O-N 3.26Å; L524-L527 HydrophobicContact CD2-CD1 4.43Å; L524-L527 PolarHBondContact O-N 3.01Å; V525-L527 VanDerWaalsContact C-N 3.25Å; V525-L527 PolarHBondContact O-N 2.76Å
528	G	72.3	Confident	66.7	Low	51 Å²	51	72.4 Å²	72.4	53%	0.526	41%	0.414	S	S	.	.	T	Hydrogen-bonded Turn	trans	90.8	21.5	174.5	0	0	0	0	0	114.5	L524 V525 A526 S530	L524-G528 PolarHBondContact O-N 3.41Å; V525-G528 PolarHBondContact O-N 3.29Å; A526-G528 PolarHBondContact O-N 2.78Å; G528-S530 PolarHBondContact O-N 3.3Å; G528-S530 PolarHBondContact O-OG 3.11Å
529	V	74.8	Confident	63.9	Low	55 Å²	55	74.2 Å²	74.2	33%	0.333	43%	0.433	S	S	.	.			trans	-74	89.5	178.4	-177.7	0	0	0	0	109.8	L524 C531 L532	L524-V529 HydrophobicContact CD2-CG2 4.33Å; L524-V529 PolarHBondContact O-N 3.31Å; V529-C531 WeakPolarHBondContact CG1-SG 3.34Å; V529-C531 PolarHBondContact O-N 2.82Å; V529-C531 VanDerWaalsContact O-N 3.09Å; V529-L532 HydrophobicContact CB-CD1 4.24Å; V529-L532 HydrophobicContact CG1-CD1 3.79Å; V529-L532 HydrophobicContact CG1-CG 4.1Å; V529-L532 PolarHBondContact O-N 3.05Å
530	S	53.7	Low	61.1	Low	107 Å²	107	78.1 Å²	78.1	75%	0.748	47%	0.473	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.9	-17	-170.6	-41.2	0	0	0	0	115.3	G528 L532	G528-S530 PolarHBondContact O-N 3.3Å; G528-S530 PolarHBondContact O-OG 3.11Å; S530-L532 VanDerWaalsContact C-N 3.34Å
531	C	53.6	Low	58.2	Low	96 Å²	96	80.5 Å²	80.5	65%	0.649	50%	0.5	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.9	-16.5	179.3	59.8	0	0	0	0	114	V529	V529-C531 WeakPolarHBondContact CG1-SG 3.34Å; V529-C531 PolarHBondContact O-N 2.82Å; V529-C531 VanDerWaalsContact O-N 3.09Å
532	L	53.7	Low	55.4	Low	47 Å²	47	80.7 Å²	80.7	25%	0.246	51%	0.509	C	S	.	.	S	Bend	trans	-94	-8.2	179.3	-62.9	168	0	0	0	112.1	W521 L524 V529 S530 C534	W521-L532 HydrophobicContact CE3-CB 4.48Å; W521-L532 HydrophobicContact CE3-CD2 4.22Å; W521-L532 HydrophobicContact CH2-CB 3.58Å; W521-L532 HydrophobicContact CH2-CD2 3.71Å; W521-L532 HydrophobicContact CH2-CG 4.17Å; W521-L532 WeakPolarHBondContact CH2-O 3.29Å; W521-L532 HydrophobicContact CZ2-CB 4.04Å; W521-L532 WeakPolarHBondContact CZ2-O 3.5Å; W521-L532 HydrophobicContact CZ3-CB 3.85Å; W521-L532 HydrophobicContact CZ3-CD1 4.33Å; W521-L532 HydrophobicContact CZ3-CD2 3.31Å; W521-L532 HydrophobicContact CZ3-CG 3.98Å; L524-L532 HydrophobicContact CB-CD1 3.84Å; L524-L532 HydrophobicContact CD1-CD1 3.8Å; L524-L532 HydrophobicContact CG-CD1 4.38Å; V529-L532 HydrophobicContact CB-CD1 4.24Å; V529-L532 HydrophobicContact CG1-CD1 3.79Å; V529-L532 HydrophobicContact CG1-CG 4.1Å; V529-L532 PolarHBondContact O-N 3.05Å; S530-L532 VanDerWaalsContact C-N 3.34Å; L532-C534 PolarHBondContact O-N 2.93Å
533	D	52.3	Low	52.8	Low	83 Å²	83	82.7 Å²	82.7	44%	0.444	53%	0.531	S	S	.	.	G	3₁₀ helix	trans	-72.2	11	174.8	-154.3	15.8	0	0	0	113.2	G535 S536	D533-G535 PolarHBondContact O-N 3.26Å; D533-G535 VanDerWaalsContact O-N 3.15Å; D533-S536 WeakPolarHBondContact O-CB 3.37Å; D533-S536 PolarHBondContact O-N 3.22Å
534	C	42.5	Very low	50.2	Low	78 Å²	78	93.2 Å²	93.2	53%	0.527	57%	0.57	S	S	.	*	G	3₁₀ helix	trans	-63.5	-17.7	-179.6	-86.8	0	0	0	0	114.2	L532 S536 R537	L532-C534 PolarHBondContact O-N 2.93Å; C534-S536 PolarHBondContact O-N 3.47Å; C534-R537 PolarHBondContact O-N 3.37Å
535	G	44.1	Very low	47.7	Very low	67 Å²	67	93.4 Å²	93.4	69%	0.691	57%	0.569	S	S	*	*	G	3₁₀ helix	trans	-64.5	-22.6	170.5	0	0	0	0	0	113.5	D533	D533-G535 PolarHBondContact O-N 3.26Å; D533-G535 VanDerWaalsContact O-N 3.15Å
536	S	38.9	Very low	45.5	Very low	69 Å²	69	95.5 Å²	95.5	48%	0.483	58%	0.582	S	S	.	*	G	3₁₀ helix	trans	-77.3	-16.1	178.1	145.5	0	0	0	0	113.7	D533 C534	D533-S536 WeakPolarHBondContact O-CB 3.37Å; D533-S536 PolarHBondContact O-N 3.22Å; C534-S536 PolarHBondContact O-N 3.47Å
537	R	34.8	Very low	43.5	Very low	225 Å²	225	101.2 Å²	101.2	85%	0.849	61%	0.61	S	S	*	*	T	Hydrogen-bonded Turn	trans	-104.7	-11.9	-173.1	-76.7	-175.9	176.6	-179	-0.3	115.4	C534	C534-R537 PolarHBondContact O-N 3.37Å
538	M	33.2	Very low	41.4	Very low	168 Å²	168	104.1 Å²	104.1	83%	0.828	63%	0.626	S	S	*	*	S	Bend	trans	-103.4	10	-172.3	-118.3	-170.5	-75.4	0	0	115.3
539	V	32.2	Very low	39.6	Very low	112 Å²	112	111 Å²	111	68%	0.679	64%	0.637	S	S	*	*	S	Bend	trans	-119.1	97.2	164.6	-178.8	0	0	0	0	107.5	G541	V539-G541 PolarHBondContact O-N 3.29Å
540	G	29.5	Very low	37.9	Very low	82 Å²	82	111.5 Å²	111.5	85%	0.845	64%	0.638	S	S	*	*	T	Hydrogen-bonded Turn	trans	-56.2	123.7	174.8	0	0	0	0	0	110.5
541	G	27.6	Very low	37	Very low	79 Å²	79	111.9 Å²	111.9	81%	0.814	63%	0.631	S	S	*	*	T	Hydrogen-bonded Turn	trans	117.5	1.6	167.7	0	0	0	0	0	117.5	V539	V539-G541 PolarHBondContact O-N 3.29Å
542	L	29.4	Very low	35.8	Very low	115 Å²	115	111.4 Å²	111.4	60%	0.602	63%	0.628	S	S	*	*			trans	-128.2	60.7	178.3	-140	80.3	0	0	0	112.2	H545	L542-H545 HydrophobicContact CD2-CB 4.38Å
543	S	29.1	Very low	34.8	Very low	116 Å²	116	116.5 Å²	116.5	81%	0.811	66%	0.656	S	S	*	*			trans	-75	129.7	171.6	-173.2	0	0	0	0	110
544	R	29.6	Very low	34	Very low	227 Å²	227	120 Å²	120	86%	0.857	67%	0.671	S	S	*	*	S	Bend	trans	83.8	51.9	177.8	-62.3	179.6	159.5	172.2	-4.9	118.7
545	H	33.7	Very low	33.6	Very low	74 Å²	74	124.8 Å²	124.8	34%	0.343	69%	0.686	S	S	.	*			trans	-127.3	1.6	176.1	-94.9	-37.9	0	0	0	118.9	L542 L548 Y549	L542-H545 HydrophobicContact CD2-CB 4.38Å; H545-L548 WeakPolarHBondContact CE1-CD2 3.14Å; H545-L548 WeakPolarHBondContact ND1-CB 3.49Å; H545-Y549 HydrophobicContact CB-CD2 4.34Å; H545-Y549 HydrophobicContact CB-CE2 4.45Å; H545-Y549 WeakPolarHBondContact O-CD2 3.41Å; H545-Y549 PolarHBondContact O-N 3.41Å
546	T	35.1	Very low	32.9	Very low	101 Å²	101	127.4 Å²	127.4	62%	0.62	69%	0.689	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76	-31.9	174.5	-26.1	0	0	0	0	112.8
547	D	33.9	Very low	32.4	Very low	136 Å²	136	130.6 Å²	130.6	73%	0.727	70%	0.701	S	S	*	*	T	Hydrogen-bonded Turn	trans	-81.7	-16.7	173.8	-69.9	-35.8	0	0	0	113.2
548	L	35	Very low	32.4	Very low	99 Å²	99	125.7 Å²	125.7	52%	0.518	70%	0.698	S	S	.	*	T	Hydrogen-bonded Turn	trans	-93.1	-22.9	-176.8	-130.2	87.3	0	0	0	114.3	H545 L550 L551 S552	H545-L548 WeakPolarHBondContact CE1-CD2 3.14Å; H545-L548 WeakPolarHBondContact ND1-CB 3.49Å; L548-L550 PolarHBondContact O-N 2.7Å; L548-L551 PolarHBondContact O-N 2.97Å; L548-S552 PolarHBondContact O-N 3.36Å
549	Y	34.9	Very low	32.2	Very low	194 Å²	194	126 Å²	126	76%	0.761	70%	0.697	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.9	-10.3	171.7	-92.9	-82.3	0	0	0	112.8	H545	H545-Y549 HydrophobicContact CB-CD2 4.34Å; H545-Y549 HydrophobicContact CB-CE2 4.45Å; H545-Y549 WeakPolarHBondContact O-CD2 3.41Å; H545-Y549 PolarHBondContact O-N 3.41Å
550	L	38.8	Very low	32.3	Very low	67 Å²	67	125.3 Å²	125.3	35%	0.351	70%	0.703	S	S	.	*	T	Hydrogen-bonded Turn	trans	-94.3	-11.2	177.8	-90	159.8	0	0	0	114.4	L548	L548-L550 PolarHBondContact O-N 2.7Å
551	L	34.2	Very low	32.5	Very low	115 Å²	115	130.4 Å²	130.4	60%	0.602	71%	0.705	S	S	*	*	T	Hydrogen-bonded Turn	trans	-121.4	-8.7	-173.9	-85.8	162.3	0	0	0	114.4	L548 D553 M554	L548-L551 PolarHBondContact O-N 2.97Å; L551-D553 VanDerWaalsContact C-N 3.29Å; L551-D553 PolarHBondContact O-N 2.93Å; L551-M554 PolarHBondContact O-N 3.01Å
552	S	29.5	Very low	32.7	Very low	86 Å²	86	142.1 Å²	142.1	60%	0.601	73%	0.725	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.5	-15.9	-176.2	-173.7	0	0	0	0	115.1	L548	L548-S552 PolarHBondContact O-N 3.36Å
553	D	33.2	Very low	32.8	Very low	154 Å²	154	143.5 Å²	143.5	82%	0.824	73%	0.731	S	S	*	*	T	Hydrogen-bonded Turn	trans	-100.5	10.3	-179.2	-76.5	-20.7	0	0	0	113.6	L551	L551-D553 VanDerWaalsContact C-N 3.29Å; L551-D553 PolarHBondContact O-N 2.93Å
554	M	35.9	Very low	33	Very low	155 Å²	155	144.9 Å²	144.9	76%	0.764	73%	0.727	S	S	*	*	S	Bend	trans	-100.1	-4.5	175.4	-80.6	-170.9	62.3	0	0	115	L551	L551-M554 PolarHBondContact O-N 3.01Å
555	E	32.9	Very low	33.2	Very low	179 Å²	179	140.4 Å²	140.4	84%	0.836	72%	0.72	S	S	*	*			trans	-139.7	76.6	176.3	-75.4	-177.9	151.4	0	0	111.2
556	T	30.2	Very low	33.2	Very low	122 Å²	122	144.3 Å²	144.3	75%	0.748	74%	0.742	S	S	*	*			trans	-134.6	84	154	39.2	0	0	0	0	109	P558	T556-P558 WeakPolarHBondContact O-CD 3.46Å
557	D	28.4	Very low	33	Very low	137 Å²	137	147 Å²	147	73%	0.733	75%	0.749	S	S	*	*			trans	-77.2	116.5	159.9	-169.1	2.1	0	0	0	107.7	Q559	D557-Q559 PolarHBondContact O-N 3.29Å
558	P	33.7	Very low	33	Very low	122 Å²	122	147.7 Å²	147.7	79%	0.792	75%	0.751	S	S	*	*	S	Bend	trans	-83.3	57.7	179.6	34.8	-33.3	0	0	0	110.5	T556	T556-P558 WeakPolarHBondContact O-CD 3.46Å
559	Q	30.2	Very low	32.9	Very low	174 Å²	174	151.2 Å²	151.2	81%	0.813	77%	0.767	S	S	*	*			trans	-146.8	68	167.3	-74.7	-143.9	-10.2	0	0	112.1	D557	D557-Q559 PolarHBondContact O-N 3.29Å
560	A	32.7	Very low	32.7	Very low	98 Å²	98	147.9 Å²	147.9	81%	0.81	77%	0.768	S	S	*	*			trans	-151.5	51.6	162.4	0	0	0	0	0	111.6
561	E	35	Very low	32.2	Very low	189 Å²	189	154.7 Å²	154.7	88%	0.883	80%	0.803	S	S	*	*			trans	-152.3	82.6	158.1	-101.8	-173.7	-176	0	0	108.9
562	R	30.3	Very low	32	Very low	325 Å²	325	158.3 Å²	158.3	100%	1.226	82%	0.821	S	S	*	*			trans	-174.5	0	143	-105	178.6	-142.6	-168.3	6.2	112.1

Retrieved 562 of 562 residues in 153.8 ms (Link to these results)

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