A0A087YE23_POEFO Loading...

Beta-enolase

AlphaFold DB , UniProt , Accession A0A087YE23, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 445 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40.7Very low43.6Very low244 Ų244149.8 Ų149.8100%1.20282%0.819SS**  0105.90-81.7173.2172.100107.7L3M1-L3 PolarHBondContact O-N 3.41Å
2A34.3Very low45.4Very low95 Ų95140.8 Ų140.879%0.78577%0.767SS**  trans-70.6121-175.600000109.9N4A2-N4 PolarHBondContact O-N 2.82Å
3L38.6Very low48.3Very low164 Ų164133.2 Ų133.286%0.85973%0.731SS**  trans-61.4111.4161.9-83143.4000107.5M1 R5M1-L3 PolarHBondContact O-N 3.41Å; L3-R5 VanDerWaalsContact C-N 3.27Å; L3-R5 PolarHBondContact O-N 3.19Å
4N40.1Very low51.7Low159 Ų159123.9 Ų123.985%0.8568%0.68SS**  trans-60.790.8169.4-87.3-16.6000109.1A2 I6A2-N4 PolarHBondContact O-N 2.82Å; N4-I6 PolarHBondContact O-N 3.23Å
5R43.8Very low54.8Low236 Ų236121.3 Ų121.389%0.89167%0.669SS**  trans-69.4107.6159.1-73.9-174.5177-168.3-0.4106.6L3L3-R5 VanDerWaalsContact C-N 3.27Å; L3-R5 PolarHBondContact O-N 3.19Å
6I43.8Very low57.5Low148 Ų148120.4 Ų120.476%0.75966%0.656SS**  trans-52.7130.7161.2-56.2174.4000105.9N4N4-I6 PolarHBondContact O-N 3.23Å
7P39.2Very low59.9Low106 Ų106113.8 Ų113.869%0.68862%0.62SS**  trans-53.3154.4174.5-19.530.3000109.1A9P7-A9 PolarHBondContact O-N 2.64Å
8A44.2Very low62.1Low107 Ų107111.3 Ų111.388%0.88460%0.603SS**  trans-64.469.7164.600000109.1V10A8-V10 PolarHBondContact O-N 3.28Å
9A47.7Very low64Low73 Ų73105.5 Ų105.560%0.60357%0.572SS**  trans-56.4126.8169.300000105.5P7 R11P7-A9 PolarHBondContact O-N 2.64Å; A9-R11 PolarHBondContact O-N 2.8Å
10V51.3Low65.8Low127 Ų127103.5 Ų103.577%0.7756%0.556SS**  trans-39.1103.1-177.2179.60000108.9A8 M12A8-V10 PolarHBondContact O-N 3.28Å; V10-M12 WeakPolarHBondContact O-CG 3.2Å; V10-M12 PolarHBondContact O-N 3.4Å
11R56.5Low67.3Low189 Ų189100.4 Ų100.471%0.71354%0.538SS*.  trans-56.4113.9175.5-77.3-177.4177.5-176.2-1.6106.1A9 S13A9-R11 PolarHBondContact O-N 2.8Å; R11-S13 PolarHBondContact O-N 2.82Å; R11-S13 VanDerWaalsContact O-N 3.13Å
12M64.3Low70.1Confident41 Ų4190.3 Ų90.320%0.20249%0.489CS..  trans-74.4114.5-168.7-58.6-146.6-64.800109.6V10 A38 K39 E136V10-M12 WeakPolarHBondContact O-CG 3.2Å; V10-M12 PolarHBondContact O-N 3.4Å; M12-A38 HydrophobicContact CE-CB 4.12Å; M12-A38 HydrophobicContact SD-CB 3.52Å; M12-A38 VanDerWaalsContact SD-CB 3.52Å; M12-K39 HydrophobicContact CE-CB 4.47Å; M12-K39 HydrophobicContact CE-CD 3.58Å; M12-K39 VanDerWaalsContact CE-CE 3.48Å; M12-K39 HydrophobicContact CE-CG 3.43Å; M12-K39 VanDerWaalsContact CE-CG 3.43Å; M12-E136 WeakPolarHBondContact CB-OE1 3.36Å; M12-E136 WeakPolarHBondContact CE-OE2 3.42Å; M12-E136 WeakPolarHBondContact CG-OE1 2.99Å
13S83.1Confident73.2Confident42 Ų4289.8 Ų89.829%0.29447%0.472SS..BIsolated β-bridgetrans-84.1154.2178.556.10000110.7R11 T15R11-S13 PolarHBondContact O-N 2.82Å; R11-S13 VanDerWaalsContact O-N 3.13Å; S13-T15 PolarHBondContact O-N 3.41Å
14I96.9Very high76Confident4 Ų482.4 Ų82.42%0.02143%0.434CS..  trans-56.4127.2169.3-58.2169.2000108.9I17 L35 L88 I89 V95 I101 V129I14-I17 HydrophobicContact CD1-CD1 4.39Å; I14-I17 HydrophobicContact CG2-CD1 3.82Å; I14-I17 HydrophobicContact CG2-CG1 3.64Å; I14-L35 HydrophobicContact CD1-CD1 4.08Å; I14-L35 HydrophobicContact CG1-CD1 4.16Å; I14-L35 HydrophobicContact CG1-CD2 4.37Å; I14-L35 HydrophobicContact CG2-CD1 4.25Å; I14-L35 HydrophobicContact CG2-CD2 4.39Å; I14-L35 HydrophobicContact CG2-CG 4.06Å; I14-L88 HydrophobicContact CD1-CB 4.35Å; I14-I89 HydrophobicContact CG2-CG1 4Å; I14-V95 HydrophobicContact CD1-CG1 4.33Å; I14-V95 HydrophobicContact CG1-CG1 3.62Å; I14-I101 HydrophobicContact CD1-CD1 4.5Å; I14-V129 HydrophobicContact CD1-CG2 4.46Å
15T96.9Very high78.8Confident84 Ų8476.1 Ų76.152%0.51540%0.402SS..  trans-101-29.1179.961.30000112.7S13 W36S13-T15 PolarHBondContact O-N 3.41Å; T15-W36 PolarHBondContact N-O 2.77Å; T15-W36 WeakPolarHBondContact OG1-CB 3.44Å; T15-W36 PolarHBondContact OG1-O 2.93Å
16K98.4Very high81.2Confident107 Ų10767.9 Ų67.947%0.46537%0.371SS..EExtended strand (participates in β ladder)trans-156145.5177.3-174.7178.3178.3-178.30109.4W36K16-W36 HydrophobicContact CB-CB 4.11Å; K16-W36 HydrophobicContact CB-CD2 4.23Å; K16-W36 HydrophobicContact CB-CE3 3.81Å; K16-W36 HydrophobicContact CB-CG 4.39Å; K16-W36 HydrophobicContact CD-CD2 4.31Å; K16-W36 HydrophobicContact CD-CE3 3.97Å; K16-W36 HydrophobicContact CD-CZ3 4.1Å; K16-W36 HydrophobicContact CG-CD2 4.48Å; K16-W36 HydrophobicContact CG-CE3 3.81Å; K16-W36 HydrophobicContact CG-CZ3 4.09Å; K16-W36 PolarHBondContact O-N 3.34Å
17I98.8Very high83.8Confident9 Ų962.7 Ų62.75%0.04635%0.354CS..EExtended strand (participates in β ladder)trans-127.1139.9163.3-67.3166.6000106.5I14 V33 D34 L35 V80 A85 L88 V125I14-I17 HydrophobicContact CD1-CD1 4.39Å; I14-I17 HydrophobicContact CG2-CD1 3.82Å; I14-I17 HydrophobicContact CG2-CG1 3.64Å; I17-V33 HydrophobicContact CG2-CG1 3.8Å; I17-D34 CarbonylContact C-O 3.54Å; I17-D34 WeakPolarHBondContact CA-O 3.28Å; I17-L35 HydrophobicContact CD1-CD1 4.17Å; I17-L35 HydrophobicContact CG1-CB 4.38Å; I17-L35 HydrophobicContact CG1-CD1 4Å; I17-L35 HydrophobicContact CG1-CG 3.97Å; I17-V80 HydrophobicContact CG2-CG1 3.79Å; I17-A85 HydrophobicContact CB-CB 3.65Å; I17-A85 HydrophobicContact CG2-CB 3.97Å; I17-L88 HydrophobicContact CD1-CB 4.14Å; I17-L88 HydrophobicContact CD1-CD1 3.79Å; I17-V125 HydrophobicContact CD1-CG1 4.15Å; I17-V125 HydrophobicContact CG2-CG2 4.38Å
18H98.9Very high86.6Confident68 Ų6858.8 Ų58.832%0.31533%0.327SS..EExtended strand (participates in β ladder)trans-144.8125.8173.8-179.753.8000110.1D34 W36 N81H18-D34 PolarHBondContact N-O 3.28Å; H18-D34 PolarHBondContact O-N 3.06Å; H18-W36 HydrophobicContact CB-CH2 3.99Å; H18-W36 HydrophobicContact CB-CZ3 3.69Å; H18-N81 WeakPolarHBondContact CA-OD1 3.35Å; H18-N81 PolarHBondContact ND1-OD1 2.92Å
19A98.9Very high89.2Confident1 Ų153.7 Ų53.71%0.00829%0.285CS..EExtended strand (participates in β ladder)trans-99.2150.4170.800000111.8V31 E32 V33 V77 V80 N81A19-V31 HydrophobicContact CB-CG1 4.39Å; A19-E32 CarbonylContact C-O 3.51Å; A19-E32 WeakPolarHBondContact CA-O 3.49Å; A19-V33 HydrophobicContact CB-CG2 4.12Å; A19-V77 HydrophobicContact CB-CB 4.43Å; A19-V77 HydrophobicContact CB-CG1 4.09Å; A19-V77 HydrophobicContact CB-CG2 4.46Å; A19-V77 WeakPolarHBondContact O-CG1 3.42Å; A19-V80 HydrophobicContact CB-CB 3.57Å; A19-V80 HydrophobicContact CB-CG1 3.59Å; A19-V80 HydrophobicContact CB-CG2 4.1Å; A19-N81 PolarHBondContact N-OD1 2.99Å; A19-N81 PolarHBondContact O-ND2 3.22Å
20R98.9Very high91.6Very high66 Ų6650.2 Ų50.225%0.24926%0.256CS..EExtended strand (participates in β ladder)trans-139.3165.6170.167.9-175.566.479.11.3110.6I22 E32 D34R20-I22 HydrophobicContact CG-CG2 4.1Å; R20-E32 VanDerWaalsContact CD-OE1 3.32Å; R20-E32 WeakPolarHBondContact CD-OE1 3.46Å; R20-E32 HydrophobicContact CG-CB 4.03Å; R20-E32 IonicContact CZ-OE1 3.56Å; R20-E32 PolarHBondContact N-O 2.99Å; R20-E32 IonicContact NE-OE1 3.21Å; R20-E32 IonicContact NH1-OE1 2.97Å; R20-E32 PolarHBondContact NH1-OE1 3.45Å; R20-E32 PolarHBondContact O-N 3.22Å; R20-D34 IonicContact CZ-OD1 3.85Å; R20-D34 IonicContact CZ-OD2 2.62Å; R20-D34 VanDerWaalsContact CZ-OD2 3.3Å; R20-D34 IonicContact NH1-OD1 3.04Å; R20-D34 PolarHBondContact NH1-OD1 2.7Å; R20-D34 IonicContact NH1-OD2 2.95Å; R20-D34 PolarHBondContact NH1-OD2 2.87Å; R20-D34 IonicContact NH2-OD2 3.79Å; R20-D34 PolarHBondContact NH2-OD2 2.86Å
21E98.7Very high93.9Very high38 Ų3844.1 Ų44.118%0.17822%0.22CC..EExtended strand (participates in β ladder)trans-93.2129.7170.9-173.7175.4-102.900109.7P29 T30 R67 T73 V77E21-P29 VanDerWaalsContact CD-CB 3.49Å; E21-P29 HydrophobicContact CG-CB 3.7Å; E21-P29 WeakPolarHBondContact OE1-CB 3.34Å; E21-T30 WeakPolarHBondContact CA-O 3.45Å; E21-R67 IonicContact OE1-NH1 3.41Å; E21-R67 PolarHBondContact OE1-NH1 3.07Å; E21-R67 IonicContact OE2-CZ 3.06Å; E21-R67 IonicContact OE2-NH1 2.81Å; E21-R67 PolarHBondContact OE2-NH1 3.09Å; E21-R67 IonicContact OE2-NH2 2.73Å; E21-R67 PolarHBondContact OE2-NH2 3.05Å; E21-T73 WeakPolarHBondContact CG-OG1 3.4Å; E21-T73 PolarHBondContact OE1-N 2.88Å; E21-T73 PolarHBondContact OE1-OG1 3.41Å; E21-V77 HydrophobicContact CB-CG2 4.36Å
22I98.8Very high95.9Very high33 Ų3335.7 Ų35.717%0.16919%0.188CC..EExtended strand (participates in β ladder)trans-123.1-178.5171.267.3165.9000109.5R20 P29 T30 E32 A45 T387R20-I22 HydrophobicContact CG-CG2 4.1Å; I22-P29 CarbonylContact O-C 3.55Å; I22-P29 VanDerWaalsContact O-CA 3.26Å; I22-P29 WeakPolarHBondContact O-CA 3.46Å; I22-T30 HydrophobicContact CD1-CG2 4.21Å; I22-T30 HydrophobicContact CG1-CG2 3.68Å; I22-T30 PolarHBondContact N-O 3.46Å; I22-T30 PolarHBondContact O-N 2.99Å; I22-E32 HydrophobicContact CD1-CB 4Å; I22-E32 HydrophobicContact CG1-CB 4.07Å; I22-E32 HydrophobicContact CG2-CB 3.85Å; I22-A45 HydrophobicContact CD1-CB 3.75Å; I22-T387 HydrophobicContact CD1-CG2 4.43Å
23L98.8Very high97.6Very high83 Ų8333.8 Ų33.844%0.43518%0.179SC..EExtended strand (participates in β ladder)trans-107.7138.8175.1-59.3-177000111.5N28 P29 Y68L23-N28 CarbonylContact C-O 3.58Å; L23-N28 WeakPolarHBondContact CA-O 2.88Å; L23-P29 HydrophobicContact CD2-CG 4.34Å; L23-Y68 HydrophobicContact CD2-CE1 3.79Å
24D98.5Very high98.3Very high10 Ų1031.9 Ų31.95%0.05317%0.165CC..  trans-77178.8170.178.83.2000111.9R26 G27 N28 T30 E386D24-R26 PolarHBondContact O-N 3.22Å; D24-R26 VanDerWaalsContact O-N 3.07Å; D24-R26 WeakPolarHBondContact OD1-CA 3.34Å; D24-R26 WeakPolarHBondContact OD1-CB 3.44Å; D24-R26 PolarHBondContact OD1-N 3.14Å; D24-R26 IonicContact OD2-NE 2.62Å; D24-R26 IonicContact OD2-NH2 3.93Å; D24-G27 PolarHBondContact O-N 3.09Å; D24-G27 PolarHBondContact OD1-N 3.49Å; D24-N28 PolarHBondContact N-O 2.77Å; D24-N28 PolarHBondContact OD1-N 2.91Å; D24-T30 HydrophobicContact CB-CG2 4.35Å; D24-E386 CarbonylContact C-O 3.58Å; D24-E386 WeakPolarHBondContact CA-O 3.28Å
25S97.8Very high98.4Very high26 Ų2631.7 Ų31.718%0.18216%0.164CC..THydrogen-bonded Turntrans-63.8-12.8-178.864.60000114.7S384 E386 R411 E413S25-S384 PolarHBondContact OG-O 2.91Å; S25-E386 WeakPolarHBondContact CB-O 3.34Å; S25-E386 PolarHBondContact N-O 2.86Å; S25-E386 PolarHBondContact OG-N 3.47Å; S25-E386 PolarHBondContact OG-O 3.28Å; S25-R411 PolarHBondContact O-NH2 3.03Å; S25-E413 VanDerWaalsContact CB-CG 3.48Å
26R96Very high98.5Very high64 Ų6430.5 Ų30.524%0.24215%0.15CC..THydrogen-bonded Turntrans-103.33175.7-60.4179-61.7175.6-4.7111.9D24 N28 S48 G49 D220D24-R26 PolarHBondContact O-N 3.22Å; D24-R26 VanDerWaalsContact O-N 3.07Å; D24-R26 WeakPolarHBondContact OD1-CA 3.34Å; D24-R26 WeakPolarHBondContact OD1-CB 3.44Å; D24-R26 PolarHBondContact OD1-N 3.14Å; D24-R26 IonicContact OD2-NE 2.62Å; D24-R26 IonicContact OD2-NH2 3.93Å; R26-N28 VanDerWaalsContact C-N 3.31Å; R26-N28 WeakPolarHBondContact CB-ND2 3.42Å; R26-S48 PolarHBondContact NH2-O 3.31Å; R26-G49 PolarHBondContact NH1-O 2.96Å; R26-G49 PolarHBondContact NH2-O 2.91Å; R26-D220 WeakPolarHBondContact CD-OD2 3.37Å
27G97.6Very high98.5Very high39 Ų3925.8 Ų25.840%0.40213%0.131SC..SBendtrans75.615.9-178.200000114D24D24-G27 PolarHBondContact O-N 3.09Å; D24-G27 PolarHBondContact OD1-N 3.49Å
28N98.3Very high98.4Very high23 Ų2329.2 Ų29.212%0.12316%0.161CC..  trans-90.3149.3173.1-56.9-67000110.1L23 D24 R26 K71L23-N28 CarbonylContact C-O 3.58Å; L23-N28 WeakPolarHBondContact CA-O 2.88Å; D24-N28 PolarHBondContact N-O 2.77Å; D24-N28 PolarHBondContact OD1-N 2.91Å; R26-N28 VanDerWaalsContact C-N 3.31Å; R26-N28 WeakPolarHBondContact CB-ND2 3.42Å; N28-K71 HydrophobicContact CB-CD 4.33Å; N28-K71 WeakPolarHBondContact OD1-CD 3.48Å; N28-K71 PolarHBondContact OD1-NZ 3.09Å; N28-K71 VanDerWaalsContact OD1-NZ 3.08Å
29P98.5Very high98.3Very high0 Ų031.8 Ų31.80%017%0.171CC..EExtended strand (participates in β ladder)trans-57.3146.8173.6-28.737.6000114.2E21 I22 L23 R61 Y68 K71 T73E21-P29 VanDerWaalsContact CD-CB 3.49Å; E21-P29 HydrophobicContact CG-CB 3.7Å; E21-P29 WeakPolarHBondContact OE1-CB 3.34Å; I22-P29 CarbonylContact O-C 3.55Å; I22-P29 VanDerWaalsContact O-CA 3.26Å; I22-P29 WeakPolarHBondContact O-CA 3.46Å; L23-P29 HydrophobicContact CD2-CG 4.34Å; P29-R61 PolarHBondContact O-NH1 3.44Å; P29-Y68 HydrophobicContact CG-CD1 3.64Å; P29-Y68 HydrophobicContact CG-CD2 3.4Å; P29-Y68 HydrophobicContact CG-CE1 4.09Å; P29-Y68 HydrophobicContact CG-CE2 3.88Å; P29-Y68 HydrophobicContact CG-CG 3.28Å; P29-K71 WeakPolarHBondContact CB-O 3.46Å; P29-K71 WeakPolarHBondContact CG-O 3.03Å; P29-T73 HydrophobicContact CB-CG2 4.29Å
30T98.8Very high98.2Very high0 Ų033.1 Ų33.10%019%0.185CC..EExtended strand (participates in β ladder)trans-149.3167.9166.9-166.10000111.3E21 I22 D24 V46 T387E21-T30 WeakPolarHBondContact CA-O 3.45Å; I22-T30 HydrophobicContact CD1-CG2 4.21Å; I22-T30 HydrophobicContact CG1-CG2 3.68Å; I22-T30 PolarHBondContact N-O 3.46Å; I22-T30 PolarHBondContact O-N 2.99Å; D24-T30 HydrophobicContact CB-CG2 4.35Å; T30-V46 WeakPolarHBondContact CB-O 3.26Å; T30-V46 WeakPolarHBondContact CG2-O 3.47Å; T30-V46 PolarHBondContact OG1-O 3.06Å; T30-T387 HydrophobicContact CG2-CG2 3.89Å
31V98.8Very high98.2Very high0 Ų033.6 Ų33.60%019%0.192CC..EExtended strand (participates in β ladder)trans-87.6129.4-177-177.40000110.5A19 V33 V46 A76 V77 N120A19-V31 HydrophobicContact CB-CG1 4.39Å; V31-V33 HydrophobicContact CG1-CG2 4.05Å; V31-V46 PolarHBondContact O-N 3.16Å; V31-A76 HydrophobicContact CG2-CB 3.79Å; V31-V77 HydrophobicContact CG1-CG2 4.45Å; V31-V77 HydrophobicContact CG2-CG2 4.31Å; V31-N120 HydrophobicContact CG2-CB 4.26Å
32E98.9Very high98.2Very high12 Ų1233.1 Ų33.16%0.05619%0.189CC..EExtended strand (participates in β ladder)trans-117.5136.6165.5-177.4-176.482.400109.6A19 R20 I22 R43 A44 A45A19-E32 CarbonylContact C-O 3.51Å; A19-E32 WeakPolarHBondContact CA-O 3.49Å; R20-E32 VanDerWaalsContact CD-OE1 3.32Å; R20-E32 WeakPolarHBondContact CD-OE1 3.46Å; R20-E32 HydrophobicContact CG-CB 4.03Å; R20-E32 IonicContact CZ-OE1 3.56Å; R20-E32 PolarHBondContact N-O 2.99Å; R20-E32 IonicContact NE-OE1 3.21Å; R20-E32 IonicContact NH1-OE1 2.97Å; R20-E32 PolarHBondContact NH1-OE1 3.45Å; R20-E32 PolarHBondContact O-N 3.22Å; I22-E32 HydrophobicContact CD1-CB 4Å; I22-E32 HydrophobicContact CG1-CB 4.07Å; I22-E32 HydrophobicContact CG2-CB 3.85Å; E32-R43 VanDerWaalsContact CD-CD 3.48Å; E32-R43 HydrophobicContact CG-CG 3.81Å; E32-R43 IonicContact OE1-NE 2.72Å; E32-R43 VanDerWaalsContact OE2-CD 3.27Å; E32-R43 WeakPolarHBondContact OE2-CD 3.43Å; E32-R43 IonicContact OE2-NE 3.83Å; E32-A44 CarbonylContact C-O 3.28Å; E32-A44 WeakPolarHBondContact CA-O 3.44Å; E32-A45 HydrophobicContact CB-CB 4.32Å; E32-A45 HydrophobicContact CG-CB 4.31Å
33V98.9Very high98.2Very high0 Ų037 Ų370%020%0.202CC..EExtended strand (participates in β ladder)trans-120.5127.1179-179.80000110I17 A19 V31 R43 A44 V80 V125 A128I17-V33 HydrophobicContact CG2-CG1 3.8Å; A19-V33 HydrophobicContact CB-CG2 4.12Å; V31-V33 HydrophobicContact CG1-CG2 4.05Å; V33-R43 CarbonylContact O-C 3.59Å; V33-R43 WeakPolarHBondContact O-CA 3.48Å; V33-A44 PolarHBondContact N-O 3.45Å; V33-A44 PolarHBondContact O-N 2.84Å; V33-V80 HydrophobicContact CG2-CG1 4.29Å; V33-V80 HydrophobicContact CG2-CG2 4.49Å; V33-V125 HydrophobicContact CG1-CG2 4.07Å; V33-V125 HydrophobicContact CG2-CG2 4.23Å; V33-A128 HydrophobicContact CG1-CB 4.24Å
34D98.9Very high98.2Very high2 Ų233 Ų331%0.01118%0.181CC..EExtended strand (participates in β ladder)trans-98.6133.9162.5-71.1-1.9000109.7I17 H18 R20 W36 L41 F42 R43I17-D34 CarbonylContact C-O 3.54Å; I17-D34 WeakPolarHBondContact CA-O 3.28Å; H18-D34 PolarHBondContact N-O 3.28Å; H18-D34 PolarHBondContact O-N 3.06Å; R20-D34 IonicContact CZ-OD1 3.85Å; R20-D34 IonicContact CZ-OD2 2.62Å; R20-D34 VanDerWaalsContact CZ-OD2 3.3Å; R20-D34 IonicContact NH1-OD1 3.04Å; R20-D34 PolarHBondContact NH1-OD1 2.7Å; R20-D34 IonicContact NH1-OD2 2.95Å; R20-D34 PolarHBondContact NH1-OD2 2.87Å; R20-D34 IonicContact NH2-OD2 3.79Å; R20-D34 PolarHBondContact NH2-OD2 2.86Å; D34-W36 HydrophobicContact CB-CE3 4.03Å; D34-W36 HydrophobicContact CB-CH2 3.11Å; D34-W36 HydrophobicContact CB-CZ2 3.85Å; D34-W36 HydrophobicContact CB-CZ3 3.21Å; D34-W36 VanDerWaalsContact O-CZ3 3.25Å; D34-W36 WeakPolarHBondContact O-CZ3 3.37Å; D34-L41 HydrophobicContact CB-CD1 4.46Å; D34-L41 HydrophobicContact CB-CD2 4.37Å; D34-L41 HydrophobicContact CB-CG 4.25Å; D34-F42 CarbonylContact C-O 3.02Å; D34-F42 WeakPolarHBondContact CA-O 3.48Å; D34-R43 WeakPolarHBondContact OD1-CB 3.28Å; D34-R43 WeakPolarHBondContact OD1-CG 3.48Å; D34-R43 IonicContact OD1-CZ 2.7Å; D34-R43 IonicContact OD1-NE 2.68Å; D34-R43 PolarHBondContact OD1-NE 3.44Å; D34-R43 IonicContact OD1-NH2 3.96Å; D34-R43 PolarHBondContact OD1-NH2 3.05Å; D34-R43 IonicContact OD2-CZ 2.85Å; D34-R43 IonicContact OD2-NE 3.86Å; D34-R43 IonicContact OD2-NH2 2.81Å; D34-R43 PolarHBondContact OD2-NH2 3.37Å
35L98.8Very high98.2Very high0 Ų032.8 Ų32.80%018%0.18CC..EExtended strand (participates in β ladder)trans-121.5132.8172.7-174.7153000108.9I14 I17 T37 F42 V95 A128 V129 A132I14-L35 HydrophobicContact CD1-CD1 4.08Å; I14-L35 HydrophobicContact CG1-CD1 4.16Å; I14-L35 HydrophobicContact CG1-CD2 4.37Å; I14-L35 HydrophobicContact CG2-CD1 4.25Å; I14-L35 HydrophobicContact CG2-CD2 4.39Å; I14-L35 HydrophobicContact CG2-CG 4.06Å; I17-L35 HydrophobicContact CD1-CD1 4.17Å; I17-L35 HydrophobicContact CG1-CB 4.38Å; I17-L35 HydrophobicContact CG1-CD1 4Å; I17-L35 HydrophobicContact CG1-CG 3.97Å; L35-T37 HydrophobicContact CD2-CG2 3.62Å; L35-F42 HydrophobicContact CD2-CD2 4.41Å; L35-F42 PolarHBondContact N-O 3.13Å; L35-F42 PolarHBondContact O-N 3.13Å; L35-V95 HydrophobicContact CD2-CG1 4.23Å; L35-A128 HydrophobicContact CB-CB 3.86Å; L35-V129 HydrophobicContact CD1-CB 4.39Å; L35-V129 HydrophobicContact CD1-CG2 3.45Å; L35-V129 VanDerWaalsContact CD1-CG2 3.45Å; L35-A132 HydrophobicContact CD2-CB 3.78Å
36W98.7Very high98.3Very high59 Ų5931.6 Ų31.622%0.22317%0.172CC..EExtended strand (participates in β ladder)trans-109.1138.4176.3-68.3-103.9000111.1T15 K16 H18 D34 G40 L41T15-W36 PolarHBondContact N-O 2.77Å; T15-W36 WeakPolarHBondContact OG1-CB 3.44Å; T15-W36 PolarHBondContact OG1-O 2.93Å; K16-W36 HydrophobicContact CB-CB 4.11Å; K16-W36 HydrophobicContact CB-CD2 4.23Å; K16-W36 HydrophobicContact CB-CE3 3.81Å; K16-W36 HydrophobicContact CB-CG 4.39Å; K16-W36 HydrophobicContact CD-CD2 4.31Å; K16-W36 HydrophobicContact CD-CE3 3.97Å; K16-W36 HydrophobicContact CD-CZ3 4.1Å; K16-W36 HydrophobicContact CG-CD2 4.48Å; K16-W36 HydrophobicContact CG-CE3 3.81Å; K16-W36 HydrophobicContact CG-CZ3 4.09Å; K16-W36 PolarHBondContact O-N 3.34Å; H18-W36 HydrophobicContact CB-CH2 3.99Å; H18-W36 HydrophobicContact CB-CZ3 3.69Å; D34-W36 HydrophobicContact CB-CE3 4.03Å; D34-W36 HydrophobicContact CB-CH2 3.11Å; D34-W36 HydrophobicContact CB-CZ2 3.85Å; D34-W36 HydrophobicContact CB-CZ3 3.21Å; D34-W36 VanDerWaalsContact O-CZ3 3.25Å; D34-W36 WeakPolarHBondContact O-CZ3 3.37Å; W36-G40 WeakPolarHBondContact CA-O 3.46Å; W36-L41 HydrophobicContact CD2-CG 4.42Å; W36-L41 HydrophobicContact CH2-CD1 4.31Å; W36-L41 HydrophobicContact CZ2-CD1 3.37Å; W36-L41 HydrophobicContact CZ2-CG 3.96Å
37T98.1Very high98.3Very high8 Ų829 Ų295%0.04916%0.164CC..EExtended strand (participates in β ladder)trans-128.7-177.4162.477.80000108.2L35 K39 G40 F42 V95 A132L35-T37 HydrophobicContact CD2-CG2 3.62Å; T37-K39 PolarHBondContact O-N 3.35Å; T37-K39 WeakPolarHBondContact OG1-CB 3.4Å; T37-K39 PolarHBondContact OG1-N 3.26Å; T37-G40 PolarHBondContact N-O 3.46Å; T37-G40 PolarHBondContact O-N 3.01Å; T37-G40 VanDerWaalsContact O-N 3.08Å; T37-F42 HydrophobicContact CG2-CD2 4.5Å; T37-F42 HydrophobicContact CG2-CE2 4.27Å; T37-V95 HydrophobicContact CG2-CG1 3.88Å; T37-V95 HydrophobicContact CG2-CG2 4.4Å; T37-A132 HydrophobicContact CG2-CB 4.11Å
38A95.9Very high98.1Very high82 Ų8227.3 Ų27.368%0.67815%0.146SC*.THydrogen-bonded Turntrans-66.2-10.1170.200000113.8M12M12-A38 HydrophobicContact CE-CB 4.12Å; M12-A38 HydrophobicContact SD-CB 3.52Å; M12-A38 VanDerWaalsContact SD-CB 3.52Å
39K96.9Very high97.3Very high121 Ų12126.7 Ų26.753%0.52614%0.144SC..THydrogen-bonded Turntrans-80.8-13.6169.5-67.1-54.7-171.2176.50113.9M12 T37 F42M12-K39 HydrophobicContact CE-CB 4.47Å; M12-K39 HydrophobicContact CE-CD 3.58Å; M12-K39 VanDerWaalsContact CE-CE 3.48Å; M12-K39 HydrophobicContact CE-CG 3.43Å; M12-K39 VanDerWaalsContact CE-CG 3.43Å; T37-K39 PolarHBondContact O-N 3.35Å; T37-K39 WeakPolarHBondContact OG1-CB 3.4Å; T37-K39 PolarHBondContact OG1-N 3.26Å; K39-F42 HydrophobicContact CB-CE2 4.05Å; K39-F42 HydrophobicContact CB-CZ 3.69Å
40G97.8Very high96Very high30 Ų3028.7 Ų28.731%0.30916%0.161SC..EExtended strand (participates in β ladder)trans125.7-155.3-178.400000113.2W36 T37 F42W36-G40 WeakPolarHBondContact CA-O 3.46Å; T37-G40 PolarHBondContact N-O 3.46Å; T37-G40 PolarHBondContact O-N 3.01Å; T37-G40 VanDerWaalsContact O-N 3.08Å; G40-F42 WeakPolarHBondContact O-CE2 3.32Å
41L98.6Very high94.3Very high75 Ų7529 Ų2939%0.39316%0.163SC..EExtended strand (participates in β ladder)trans-99.5131.8-177.7-177.6163.6000110.1D34 W36 R43D34-L41 HydrophobicContact CB-CD1 4.46Å; D34-L41 HydrophobicContact CB-CD2 4.37Å; D34-L41 HydrophobicContact CB-CG 4.25Å; W36-L41 HydrophobicContact CD2-CG 4.42Å; W36-L41 HydrophobicContact CH2-CD1 4.31Å; W36-L41 HydrophobicContact CZ2-CD1 3.37Å; W36-L41 HydrophobicContact CZ2-CG 3.96Å; L41-R43 HydrophobicContact CD2-CB 3.98Å
42F98.8Very high93.2Very high28 Ų2832.4 Ų32.412%0.12318%0.184CC..EExtended strand (participates in β ladder)trans-121.3123.2175.7-56.7-78.8000109.3D34 L35 T37 K39 G40 K131 A132 A135D34-F42 CarbonylContact C-O 3.02Å; D34-F42 WeakPolarHBondContact CA-O 3.48Å; L35-F42 HydrophobicContact CD2-CD2 4.41Å; L35-F42 PolarHBondContact N-O 3.13Å; L35-F42 PolarHBondContact O-N 3.13Å; T37-F42 HydrophobicContact CG2-CD2 4.5Å; T37-F42 HydrophobicContact CG2-CE2 4.27Å; K39-F42 HydrophobicContact CB-CE2 4.05Å; K39-F42 HydrophobicContact CB-CZ 3.69Å; G40-F42 WeakPolarHBondContact O-CE2 3.32Å; F42-K131 HydrophobicContact CB-CB 4.13Å; F42-K131 HydrophobicContact CD1-CB 4.27Å; F42-A132 HydrophobicContact CB-CB 4.17Å; F42-A132 HydrophobicContact CD1-CB 4.29Å; F42-A132 HydrophobicContact CD2-CB 3.38Å; F42-A132 HydrophobicContact CE2-CB 3.82Å; F42-A132 HydrophobicContact CG-CB 3.64Å; F42-A132 HydrophobicContact CZ-CB 4.44Å; F42-A135 HydrophobicContact CD1-CB 4.38Å; F42-A135 HydrophobicContact CE1-CB 3.24Å; F42-A135 HydrophobicContact CZ-CB 3.38Å
43R98.9Very high92.1Very high114 Ų11432 Ų3243%0.4318%0.183SC..EExtended strand (participates in β ladder)trans-115.2136.6-172.5178.1172.3-70.7168.15.4111E32 V33 D34 L41 K131E32-R43 VanDerWaalsContact CD-CD 3.48Å; E32-R43 HydrophobicContact CG-CG 3.81Å; E32-R43 IonicContact OE1-NE 2.72Å; E32-R43 VanDerWaalsContact OE2-CD 3.27Å; E32-R43 WeakPolarHBondContact OE2-CD 3.43Å; E32-R43 IonicContact OE2-NE 3.83Å; V33-R43 CarbonylContact O-C 3.59Å; V33-R43 WeakPolarHBondContact O-CA 3.48Å; D34-R43 WeakPolarHBondContact OD1-CB 3.28Å; D34-R43 WeakPolarHBondContact OD1-CG 3.48Å; D34-R43 IonicContact OD1-CZ 2.7Å; D34-R43 IonicContact OD1-NE 2.68Å; D34-R43 PolarHBondContact OD1-NE 3.44Å; D34-R43 IonicContact OD1-NH2 3.96Å; D34-R43 PolarHBondContact OD1-NH2 3.05Å; D34-R43 IonicContact OD2-CZ 2.85Å; D34-R43 IonicContact OD2-NE 3.86Å; D34-R43 IonicContact OD2-NH2 2.81Å; D34-R43 PolarHBondContact OD2-NH2 3.37Å; L41-R43 HydrophobicContact CD2-CB 3.98Å; R43-K131 WeakPolarHBondContact O-CD 3.33Å; R43-K131 WeakPolarHBondContact O-CE 3.44Å; R43-K131 PolarHBondContact O-NZ 3.04Å
44A98.8Very high91.3Very high0 Ų036.9 Ų36.90%021%0.213CC..EExtended strand (participates in β ladder)trans-138.3142.1169.100000112.3E32 V33 L127 A128 K131 D389E32-A44 CarbonylContact C-O 3.28Å; E32-A44 WeakPolarHBondContact CA-O 3.44Å; V33-A44 PolarHBondContact N-O 3.45Å; V33-A44 PolarHBondContact O-N 2.84Å; A44-L127 HydrophobicContact CB-CB 3.38Å; A44-L127 HydrophobicContact CB-CD1 4.29Å; A44-L127 HydrophobicContact CB-CG 4.49Å; A44-A128 HydrophobicContact CB-CB 4.15Å; A44-K131 HydrophobicContact CB-CD 4.4Å; A44-D389 WeakPolarHBondContact CA-OD2 3.3Å
45A98.8Very high90.8Very high5 Ų540.2 Ų40.24%0.04123%0.228CC..EExtended strand (participates in β ladder)trans-118.1147.8174.700000111.2I22 E32 T387 D389I22-A45 HydrophobicContact CD1-CB 3.75Å; E32-A45 HydrophobicContact CB-CB 4.32Å; E32-A45 HydrophobicContact CG-CB 4.31Å; A45-T387 HydrophobicContact CB-CG2 3.9Å; A45-D389 HydrophobicContact CB-CB 4.35Å; A45-D389 PolarHBondContact N-OD2 3.11Å
46V98.6Very high90.4Very high1 Ų141.4 Ų41.41%0.00623%0.234CC..  trans-99.8131.8-174.6175.40000110.6T30 V31 N120 L123 N356T30-V46 WeakPolarHBondContact CB-O 3.26Å; T30-V46 WeakPolarHBondContact CG2-O 3.47Å; T30-V46 PolarHBondContact OG1-O 3.06Å; V31-V46 PolarHBondContact O-N 3.16Å; V46-N120 HydrophobicContact CG1-CB 3.95Å; V46-N120 WeakPolarHBondContact CG2-O 3.41Å; V46-L123 HydrophobicContact CG1-CD2 3.87Å; V46-L123 HydrophobicContact CG2-CB 4.19Å; V46-L123 HydrophobicContact CG2-CD2 4.21Å; V46-L123 HydrophobicContact CG2-CG 4.29Å; V46-N356 HydrophobicContact CG1-CB 4.39Å
47P97.8Very high90.2Very high11 Ų1139.1 Ų39.17%0.07123%0.228CC..  trans-80.6166.1174.235.4-37.1000111.9N356 R383 G385P47-N356 HydrophobicContact CG-CB 4.32Å; P47-N356 PolarHBondContact O-ND2 3.29Å; P47-R383 HydrophobicContact CB-CB 4.02Å; P47-R383 HydrophobicContact CB-CG 3.85Å; P47-R383 HydrophobicContact CG-CG 3.96Å; P47-G385 CarbonylContact C-O 3.58Å; P47-G385 WeakPolarHBondContact CA-O 3.26Å; P47-G385 WeakPolarHBondContact CB-O 3.27Å
48S92.6Very high90Very high3 Ų342.1 Ų42.12%0.02124%0.243CC..BIsolated β-bridgetrans-135.3143.4179.3-179.90000112R26 E59 R61 R383 G385R26-S48 PolarHBondContact NH2-O 3.31Å; S48-E59 PolarHBondContact OG-OE1 3.04Å; S48-E59 PolarHBondContact OG-OE2 3.47Å; S48-R61 PolarHBondContact OG-NH2 3.45Å; S48-R383 WeakPolarHBondContact O-CB 3.26Å; S48-G385 PolarHBondContact N-O 2.96Å; S48-G385 CarbonylContact O-C 3.58Å; S48-G385 WeakPolarHBondContact O-CA 3.39Å; S48-G385 PolarHBondContact O-N 3.18Å
49G81.9Confident90Very high9 Ų940.4 Ų40.49%0.09322%0.221CC..  trans-84167.1-179.600000115.1R26R26-G49 PolarHBondContact NH1-O 2.96Å; R26-G49 PolarHBondContact NH2-O 2.91Å
50A71.4Confident90Very high42 Ų4235.9 Ų35.935%0.34720%0.202SC..SBendtrans-107.3-60.5166.800000109.7S384A50-S384 VanDerWaalsContact CB-OG 3.22Å; A50-S384 WeakPolarHBondContact CB-OG 3.4Å; A50-S384 PolarHBondContact N-OG 2.62Å
51S62.7Low90Very high6 Ų637 Ų374%0.04220%0.197CC..SBendtrans-79.3122.5159.556.20000108R383S51-R383 PolarHBondContact O-NH2 3.35Å
52T75.8Confident90Very high72 Ų7234.4 Ų34.444%0.44218%0.184SC..  trans-126117.1177.255.40000107.6E56T52-E56 WeakPolarHBondContact CA-OE1 3.42Å
53G74.9Confident89.9Confident4 Ų435.7 Ų35.74%0.04120%0.204CC..  trans-54144.2171.300000111H55 E56 D330G53-H55 PolarHBondContact O-N 3.08Å; G53-E56 PolarHBondContact N-OE1 3.39Å; G53-E56 WeakPolarHBondContact O-CG 2.87Å; G53-E56 PolarHBondContact O-N 3Å; G53-D330 WeakPolarHBondContact CA-OD1 3.19Å; G53-D330 PolarHBondContact N-OD1 3.49Å
54V83.1Confident89.8Confident102 Ų10233.8 Ų33.862%0.61820%0.203SC*.THydrogen-bonded Turntrans-68.4-9.9-172.7-59.50000113.2
55H88.4Confident89.7Confident72 Ų7242.7 Ų42.733%0.33324%0.242SC..THydrogen-bonded Turntrans-106.33.4-177.7-60.5-58000113.9G53 D310 V333 R338G53-H55 PolarHBondContact O-N 3.08Å; H55-D310 IonicContact NE2-OD1 3.38Å; H55-D310 IonicContact NE2-OD2 2.75Å; H55-V333 HydrophobicContact CB-CG1 4.39Å; H55-V333 HydrophobicContact CB-CG2 3.71Å; H55-R338 VanDerWaalsContact CD2-CZ 3.42Å; H55-R338 PolarHBondContact CD2-NH1 3.2Å; H55-R338 PolarHBondContact NE2-NH1 3.34Å
56E90.9Very high89.7Confident25 Ų2547.5 Ų47.512%0.11728%0.275CS..SBendtrans-60.1153.4175.1-68.9-169.6-164.200111.7T52 G53 V333 Q357 R383T52-E56 WeakPolarHBondContact CA-OE1 3.42Å; G53-E56 PolarHBondContact N-OE1 3.39Å; G53-E56 WeakPolarHBondContact O-CG 2.87Å; G53-E56 PolarHBondContact O-N 3Å; E56-V333 HydrophobicContact CG-CB 4.05Å; E56-V333 HydrophobicContact CG-CG1 3.67Å; E56-Q357 VanDerWaalsContact CD-CG 3.45Å; E56-Q357 HydrophobicContact CG-CB 4.13Å; E56-Q357 HydrophobicContact CG-CG 3.77Å; E56-Q357 PolarHBondContact OE1-NE2 2.68Å; E56-R383 IonicContact OE1-CZ 2.97Å; E56-R383 IonicContact OE1-NH1 2.75Å; E56-R383 IonicContact OE1-NH2 2.91Å; E56-R383 PolarHBondContact OE1-NH2 3.11Å; E56-R383 IonicContact OE2-CZ 3.95Å; E56-R383 IonicContact OE2-NH1 3.45Å; E56-R383 PolarHBondContact OE2-NH1 2.99Å; E56-R383 IonicContact OE2-NH2 2.53Å; E56-R383 PolarHBondContact OE2-NH2 3.03Å
57A93.4Very high89.6Confident12 Ų1251.4 Ų51.410%0.09929%0.29CS..PPolyproline II helixtrans-59.6144.9164.700000110.3E59 K114 A119 Q357A57-E59 PolarHBondContact O-N 2.78Å; A57-K114 HydrophobicContact CB-CD 4.16Å; A57-A119 HydrophobicContact CB-CB 3.6Å; A57-Q357 WeakPolarHBondContact CB-O 3.31Å; A57-Q357 PolarHBondContact N-O 3.01Å
58L94.7Very high89.6Confident70 Ų7056 Ų5637%0.36631%0.306SS..PPolyproline II helixtrans-71.8120-168.3-176.471.5000111.6L60 N113 G118 A119L58-L60 PolarHBondContact O-N 3.12Å; L58-N113 PolarHBondContact N-O 3.08Å; L58-G118 CarbonylContact O-C 3.51Å; L58-G118 WeakPolarHBondContact O-CA 3.46Å; L58-A119 WeakPolarHBondContact O-CB 3.4Å; L58-A119 PolarHBondContact O-N 3.1Å
59E95.6Very high89.9Confident46 Ų4662.8 Ų62.822%0.21534%0.342CS..  trans-76.8111.5163.1-172.5179.9173.200110S48 A57 R61 N120S48-E59 PolarHBondContact OG-OE1 3.04Å; S48-E59 PolarHBondContact OG-OE2 3.47Å; A57-E59 PolarHBondContact O-N 2.78Å; E59-R61 PolarHBondContact O-N 2.92Å; E59-R61 IonicContact OE1-CZ 2.77Å; E59-R61 IonicContact OE1-NE 2.7Å; E59-R61 PolarHBondContact OE1-NE 3.18Å; E59-R61 IonicContact OE1-NH2 2.66Å; E59-R61 PolarHBondContact OE1-NH2 3.04Å; E59-R61 IonicContact OE2-NH2 3.5Å; E59-N120 HydrophobicContact CG-CB 4.24Å
60L97.1Very high90.6Very high27 Ų2763 Ų6314%0.14134%0.343CS..  trans-79.2117-177.2-177.565.5000111L58 K75 A76 H79 F117 N120L58-L60 PolarHBondContact O-N 3.12Å; L60-K75 HydrophobicContact CD2-CB 3.96Å; L60-K75 HydrophobicContact CG-CB 4.32Å; L60-A76 HydrophobicContact CB-CB 4.38Å; L60-A76 HydrophobicContact CD2-CB 4.44Å; L60-H79 VanDerWaalsContact CD2-CD2 3.48Å; L60-H79 WeakPolarHBondContact CD2-CD2 3.19Å; L60-F117 WeakPolarHBondContact CD2-O 3.21Å; L60-N120 PolarHBondContact N-OD1 3.36Å; L60-N120 PolarHBondContact O-ND2 3.03Å
61R97.6Very high91.8Very high54 Ų5465 Ų6520%0.20434%0.344CS..  trans-112.6155.2175.1-61.5-65.7-170.4160.1-6.4111.5P29 S48 E59 K71 G72P29-R61 PolarHBondContact O-NH1 3.44Å; S48-R61 PolarHBondContact OG-NH2 3.45Å; E59-R61 PolarHBondContact O-N 2.92Å; E59-R61 IonicContact OE1-CZ 2.77Å; E59-R61 IonicContact OE1-NE 2.7Å; E59-R61 PolarHBondContact OE1-NE 3.18Å; E59-R61 IonicContact OE1-NH2 2.66Å; E59-R61 PolarHBondContact OE1-NH2 3.04Å; E59-R61 IonicContact OE2-NH2 3.5Å; R61-K71 PolarHBondContact NH1-O 2.9Å; R61-G72 CarbonylContact C-O 3.59Å; R61-G72 WeakPolarHBondContact CA-O 3.28Å
62D97.6Very high93.5Very high20 Ų2064.7 Ų64.711%0.10734%0.342CS..  trans-71.2-35.3-175.8-66.9-19.7000112.5D64 R67 G72 T73 Q74 K75D62-D64 PolarHBondContact O-N 3.38Å; D62-R67 IonicContact OD2-NH1 3.87Å; D62-G72 VanDerWaalsContact CG-O 3.31Å; D62-G72 PolarHBondContact N-O 3.33Å; D62-G72 WeakPolarHBondContact OD2-CA 3.37Å; D62-T73 PolarHBondContact OD2-N 3.12Å; D62-Q74 VanDerWaalsContact CG-N 3.34Å; D62-Q74 PolarHBondContact OD1-N 3.01Å; D62-Q74 WeakPolarHBondContact OD2-CB 3.46Å; D62-Q74 PolarHBondContact OD2-N 3.28Å; D62-K75 WeakPolarHBondContact O-CE 3.47Å; D62-K75 PolarHBondContact O-NZ 3.47Å; D62-K75 WeakPolarHBondContact OD1-CG 3.33Å; D62-K75 PolarHBondContact OD1-N 3.18Å
63G96.9Very high94.6Very high54 Ų5461.3 Ų61.356%0.55732%0.321SS*.  trans74.92-177.600000114.7K65 G70G63-K65 PolarHBondContact O-N 3.25Å; G63-G70 WeakPolarHBondContact CA-O 3.46Å; G63-G70 PolarHBondContact N-O 3.43Å
64D97.4Very high95.8Very high75 Ų7564.8 Ų64.840%0.40134%0.337SS..  trans-75.6101.6177.3178.73000111.2D62 S66 R67 G70D62-D64 PolarHBondContact O-N 3.38Å; D64-S66 VanDerWaalsContact CG-OG 3.25Å; D64-S66 PolarHBondContact O-N 2.86Å; D64-S66 WeakPolarHBondContact OD1-CB 3.43Å; D64-S66 PolarHBondContact OD1-N 3.31Å; D64-S66 PolarHBondContact OD1-OG 3.29Å; D64-S66 PolarHBondContact OD2-OG 2.78Å; D64-R67 HydrophobicContact CB-CB 4.5Å; D64-R67 PolarHBondContact O-N 3.35Å; D64-G70 WeakPolarHBondContact O-CA 3.35Å; D64-G70 PolarHBondContact O-N 3.43Å
65K97.1Very high96.5Very high186 Ų18664.8 Ų64.881%0.80933%0.328SS*.THydrogen-bonded Turntrans-59.4-20.8-179.1-66.2-174.2178.3-178.80113.8G63 R67G63-K65 PolarHBondContact O-N 3.25Å; K65-R67 VanDerWaalsContact C-N 3.33Å
66S97.6Very high97Very high107 Ų10761.3 Ų61.375%0.74831%0.312SS*.THydrogen-bonded Turntrans-78.9-15.6177.976.30000113.5D64D64-S66 VanDerWaalsContact CG-OG 3.25Å; D64-S66 PolarHBondContact O-N 2.86Å; D64-S66 WeakPolarHBondContact OD1-CB 3.43Å; D64-S66 PolarHBondContact OD1-N 3.31Å; D64-S66 PolarHBondContact OD1-OG 3.29Å; D64-S66 PolarHBondContact OD2-OG 2.78Å
67R98Very high97.4Very high83 Ų8360.3 Ų60.331%0.31331%0.308SS..SBendtrans-124.9120.3-176.9-171.8-177-174.7-85.2-7.1111.1E21 D62 D64 K65 L69 G70E21-R67 IonicContact OE1-NH1 3.41Å; E21-R67 PolarHBondContact OE1-NH1 3.07Å; E21-R67 IonicContact OE2-CZ 3.06Å; E21-R67 IonicContact OE2-NH1 2.81Å; E21-R67 PolarHBondContact OE2-NH1 3.09Å; E21-R67 IonicContact OE2-NH2 2.73Å; E21-R67 PolarHBondContact OE2-NH2 3.05Å; D62-R67 IonicContact OD2-NH1 3.87Å; D64-R67 HydrophobicContact CB-CB 4.5Å; D64-R67 PolarHBondContact O-N 3.35Å; K65-R67 VanDerWaalsContact C-N 3.33Å; R67-L69 PolarHBondContact O-N 2.78Å; R67-G70 PolarHBondContact O-N 3.49Å
68Y97.6Very high97.6Very high106 Ų10662.1 Ų62.142%0.41632%0.316SS..G310 helixtrans47.636.4-178.3-69.9-74.9000113.4L23 P29 G70 K71L23-Y68 HydrophobicContact CD2-CE1 3.79Å; P29-Y68 HydrophobicContact CG-CD1 3.64Å; P29-Y68 HydrophobicContact CG-CD2 3.4Å; P29-Y68 HydrophobicContact CG-CE1 4.09Å; P29-Y68 HydrophobicContact CG-CE2 3.88Å; P29-Y68 HydrophobicContact CG-CG 3.28Å; Y68-G70 PolarHBondContact O-N 3.29Å; Y68-K71 VanDerWaalsContact O-CB 3.29Å; Y68-K71 WeakPolarHBondContact O-CB 3.36Å; Y68-K71 PolarHBondContact O-N 3.19Å
69L97.2Very high97.8Very high147 Ų14760.6 Ų60.677%0.7731%0.307SS*.G310 helixtrans56.731.5179.5-46.7177.1000113.8R67R67-L69 PolarHBondContact O-N 2.78Å
70G97.2Very high98Very high12 Ų1258.4 Ų58.412%0.12430%0.297CS..G310 helixtrans89.5-3.7-176.900000114.9G63 D64 R67 Y68G63-G70 WeakPolarHBondContact CA-O 3.46Å; G63-G70 PolarHBondContact N-O 3.43Å; D64-G70 WeakPolarHBondContact O-CA 3.35Å; D64-G70 PolarHBondContact O-N 3.43Å; R67-G70 PolarHBondContact O-N 3.49Å; Y68-G70 PolarHBondContact O-N 3.29Å
71K98Very high98.1Very high85 Ų8559.3 Ų59.337%0.3730%0.301SS..THydrogen-bonded Turntrans-95.313.6-173.8-56.8177.2177.8179.70114N28 P29 R61 Y68N28-K71 HydrophobicContact CB-CD 4.33Å; N28-K71 WeakPolarHBondContact OD1-CD 3.48Å; N28-K71 PolarHBondContact OD1-NZ 3.09Å; N28-K71 VanDerWaalsContact OD1-NZ 3.08Å; P29-K71 WeakPolarHBondContact CB-O 3.46Å; P29-K71 WeakPolarHBondContact CG-O 3.03Å; R61-K71 PolarHBondContact NH1-O 2.9Å; Y68-K71 VanDerWaalsContact O-CB 3.29Å; Y68-K71 WeakPolarHBondContact O-CB 3.36Å; Y68-K71 PolarHBondContact O-N 3.19Å
72G98.4Very high98.1Very high0 Ų063.3 Ų63.30%032%0.32CS..  trans-56156.8170.900000112.5R61 D62R61-G72 CarbonylContact C-O 3.59Å; R61-G72 WeakPolarHBondContact CA-O 3.28Å; D62-G72 VanDerWaalsContact CG-O 3.31Å; D62-G72 PolarHBondContact N-O 3.33Å; D62-G72 WeakPolarHBondContact OD2-CA 3.37Å
73T98.5Very high98.2Very high0 Ų065.9 Ų65.90%033%0.332CS..  trans-125.618.9178.457.30000112.3E21 P29 D62 K75 A76 V77E21-T73 WeakPolarHBondContact CG-OG1 3.4Å; E21-T73 PolarHBondContact OE1-N 2.88Å; E21-T73 PolarHBondContact OE1-OG1 3.41Å; P29-T73 HydrophobicContact CB-CG2 4.29Å; D62-T73 PolarHBondContact OD2-N 3.12Å; T73-K75 PolarHBondContact O-N 3.09Å; T73-A76 PolarHBondContact O-N 3.05Å; T73-A76 VanDerWaalsContact O-N 3.1Å; T73-V77 WeakPolarHBondContact O-CG2 3.34Å; T73-V77 PolarHBondContact O-N 2.9Å
74Q98.6Very high98.2Very high77 Ų7763.3 Ų63.336%0.3631%0.305SS..Hα-helixtrans-60.9-34.3-176.8-169.961.66000112D62 V77 D78D62-Q74 VanDerWaalsContact CG-N 3.34Å; D62-Q74 PolarHBondContact OD1-N 3.01Å; D62-Q74 WeakPolarHBondContact OD2-CB 3.46Å; D62-Q74 PolarHBondContact OD2-N 3.28Å; Q74-V77 PolarHBondContact O-N 3.17Å; Q74-D78 PolarHBondContact NE2-OD1 3.14Å; Q74-D78 VanDerWaalsContact O-CB 3.26Å; Q74-D78 WeakPolarHBondContact O-CB 3.39Å; Q74-D78 VanDerWaalsContact O-CG 3.29Å; Q74-D78 PolarHBondContact O-N 3.26Å
75K98.6Very high98.3Very high102 Ų10260 Ų6044%0.44329%0.288SS..Hα-helixtrans-60.8-47.6173.7-68.8177.6-168.4168.10112.1L60 D62 T73 D78 H79L60-K75 HydrophobicContact CD2-CB 3.96Å; L60-K75 HydrophobicContact CG-CB 4.32Å; D62-K75 WeakPolarHBondContact O-CE 3.47Å; D62-K75 PolarHBondContact O-NZ 3.47Å; D62-K75 WeakPolarHBondContact OD1-CG 3.33Å; D62-K75 PolarHBondContact OD1-N 3.18Å; T73-K75 PolarHBondContact O-N 3.09Å; K75-D78 WeakPolarHBondContact O-CB 3.4Å; K75-D78 PolarHBondContact O-N 3.27Å; K75-H79 PolarHBondContact O-CD2 3.04Å; K75-H79 PolarHBondContact O-N 2.77Å
76A98.6Very high98.4Very high0 Ų054.3 Ų54.30%027%0.27CS..Hα-helixtrans-63.6-43.9178.100000111.4V31 L60 T73 D78 H79 V80 A121V31-A76 HydrophobicContact CG2-CB 3.79Å; L60-A76 HydrophobicContact CB-CB 4.38Å; L60-A76 HydrophobicContact CD2-CB 4.44Å; T73-A76 PolarHBondContact O-N 3.05Å; T73-A76 VanDerWaalsContact O-N 3.1Å; A76-D78 VanDerWaalsContact C-N 3.29Å; A76-D78 PolarHBondContact O-N 3.48Å; A76-H79 PolarHBondContact O-N 3.04Å; A76-V80 WeakPolarHBondContact O-CG2 3.3Å; A76-V80 PolarHBondContact O-N 2.82Å; A76-A121 HydrophobicContact CB-CB 4.26Å
77V98.9Very high98.4Very high4 Ų452.8 Ų52.82%0.02425%0.251CS..Hα-helixtrans-58-42173.4168.80000111.5A19 E21 V31 T73 Q74 V80 N81A19-V77 HydrophobicContact CB-CB 4.43Å; A19-V77 HydrophobicContact CB-CG1 4.09Å; A19-V77 HydrophobicContact CB-CG2 4.46Å; A19-V77 WeakPolarHBondContact O-CG1 3.42Å; E21-V77 HydrophobicContact CB-CG2 4.36Å; V31-V77 HydrophobicContact CG1-CG2 4.45Å; V31-V77 HydrophobicContact CG2-CG2 4.31Å; T73-V77 WeakPolarHBondContact O-CG2 3.34Å; T73-V77 PolarHBondContact O-N 2.9Å; Q74-V77 PolarHBondContact O-N 3.17Å; V77-V80 PolarHBondContact O-N 3.43Å; V77-N81 WeakPolarHBondContact CG1-ND2 3.44Å; V77-N81 WeakPolarHBondContact O-CB 3.32Å; V77-N81 PolarHBondContact O-N 3.33Å; V77-N81 PolarHBondContact O-ND2 3.41Å
78D98.8Very high98.3Very high49 Ų4948.9 Ų48.926%0.26224%0.236SC..Hα-helixtrans-66.2-42.6177.9-8413.2000112Q74 K75 A76 V80 N81 K82Q74-D78 PolarHBondContact NE2-OD1 3.14Å; Q74-D78 VanDerWaalsContact O-CB 3.26Å; Q74-D78 WeakPolarHBondContact O-CB 3.39Å; Q74-D78 VanDerWaalsContact O-CG 3.29Å; Q74-D78 PolarHBondContact O-N 3.26Å; K75-D78 WeakPolarHBondContact O-CB 3.4Å; K75-D78 PolarHBondContact O-N 3.27Å; A76-D78 VanDerWaalsContact C-N 3.29Å; A76-D78 PolarHBondContact O-N 3.48Å; D78-V80 VanDerWaalsContact C-N 3.32Å; D78-V80 PolarHBondContact O-N 2.72Å; D78-N81 PolarHBondContact O-N 2.8Å; D78-K82 HydrophobicContact CB-CD 4.29Å; D78-K82 VanDerWaalsContact O-CB 3.24Å; D78-K82 WeakPolarHBondContact O-CB 3.48Å; D78-K82 WeakPolarHBondContact O-CG 3.29Å; D78-K82 PolarHBondContact O-N 3.45Å; D78-K82 IonicContact OD1-NZ 3.53Å; D78-K82 IonicContact OD2-NZ 3.38Å; D78-K82 PolarHBondContact OD2-NZ 2.58Å
79H98.8Very high98.3Very high39 Ų3946.6 Ų46.618%0.18123%0.231CC..Hα-helixtrans-59.4-42.4174.1-70.6-54.4000111.8L60 K75 A76 E83 I84 K116 F117L60-H79 VanDerWaalsContact CD2-CD2 3.48Å; L60-H79 WeakPolarHBondContact CD2-CD2 3.19Å; K75-H79 PolarHBondContact O-CD2 3.04Å; K75-H79 PolarHBondContact O-N 2.77Å; A76-H79 PolarHBondContact O-N 3.04Å; H79-E83 IonicContact CE1-OE1 2.72Å; H79-E83 PolarHBondContact CE1-OE1 3.49Å; H79-E83 IonicContact CG-OE1 2.87Å; H79-E83 IonicContact ND1-OE1 3.31Å; H79-E83 PolarHBondContact ND1-OE1 3.34Å; H79-E83 WeakPolarHBondContact O-CA 3.33Å; H79-E83 WeakPolarHBondContact O-CB 3.44Å; H79-E83 PolarHBondContact O-N 2.89Å; H79-I84 PolarHBondContact O-N 3.07Å; H79-K116 PolarHBondContact NE2-O 3.34Å; H79-F117 HydrophobicContact CB-CB 4.31Å; H79-F117 HydrophobicContact CB-CD1 3.94Å; H79-F117 HydrophobicContact CB-CG 4.38Å; H79-F117 AromaticContact CG-CD1 3.8Å; H79-F117 AromaticContact ND1-CD1 3.74Å
80V98.9Very high98.3Very high0 Ų046.3 Ų46.30%023%0.226CC..Iπ-helixtrans-60.9-52.1175.1177.40000110.8I17 A19 V33 A76 V77 D78 I84 A85 A121 V125I17-V80 HydrophobicContact CG2-CG1 3.79Å; A19-V80 HydrophobicContact CB-CB 3.57Å; A19-V80 HydrophobicContact CB-CG1 3.59Å; A19-V80 HydrophobicContact CB-CG2 4.1Å; V33-V80 HydrophobicContact CG2-CG1 4.29Å; V33-V80 HydrophobicContact CG2-CG2 4.49Å; A76-V80 WeakPolarHBondContact O-CG2 3.3Å; A76-V80 PolarHBondContact O-N 2.82Å; V77-V80 PolarHBondContact O-N 3.43Å; D78-V80 VanDerWaalsContact C-N 3.32Å; D78-V80 PolarHBondContact O-N 2.72Å; V80-I84 HydrophobicContact CG2-CD1 4.31Å; V80-A85 WeakPolarHBondContact O-CB 3.48Å; V80-A85 PolarHBondContact O-N 3.48Å; V80-A121 HydrophobicContact CG2-CB 3.69Å; V80-V125 HydrophobicContact CG1-CG2 3.7Å; V80-V125 HydrophobicContact CG2-CG2 4.2Å
81N98.9Very high98.2Very high45 Ų4550.4 Ų50.424%0.24124%0.24CC..Iπ-helixtrans-70.6-37.1-172.9-75.8-45.8000113.7H18 A19 V77 D78H18-N81 WeakPolarHBondContact CA-OD1 3.35Å; H18-N81 PolarHBondContact ND1-OD1 2.92Å; A19-N81 PolarHBondContact N-OD1 2.99Å; A19-N81 PolarHBondContact O-ND2 3.22Å; V77-N81 WeakPolarHBondContact CG1-ND2 3.44Å; V77-N81 WeakPolarHBondContact O-CB 3.32Å; V77-N81 PolarHBondContact O-N 3.33Å; V77-N81 PolarHBondContact O-ND2 3.41Å; D78-N81 PolarHBondContact O-N 2.8Å
82K98.7Very high98Very high138 Ų13853.9 Ų53.960%0.626%0.255SS*.Iπ-helixtrans-102-24.6-169.1-59.4175.5-176.41670113.4D78D78-K82 HydrophobicContact CB-CD 4.29Å; D78-K82 VanDerWaalsContact O-CB 3.24Å; D78-K82 WeakPolarHBondContact O-CB 3.48Å; D78-K82 WeakPolarHBondContact O-CG 3.29Å; D78-K82 PolarHBondContact O-N 3.45Å; D78-K82 IonicContact OD1-NZ 3.53Å; D78-K82 IonicContact OD2-NZ 3.38Å; D78-K82 PolarHBondContact OD2-NZ 2.58Å
83E98.6Very high97.9Very high75 Ų7555.1 Ų55.135%0.3526%0.261SS..Iπ-helixtrans-119.3-54.6-174.4-62.9-176.6-110.400112.6H79 Q87 F117H79-E83 IonicContact CE1-OE1 2.72Å; H79-E83 PolarHBondContact CE1-OE1 3.49Å; H79-E83 IonicContact CG-OE1 2.87Å; H79-E83 IonicContact ND1-OE1 3.31Å; H79-E83 PolarHBondContact ND1-OE1 3.34Å; H79-E83 WeakPolarHBondContact O-CA 3.33Å; H79-E83 WeakPolarHBondContact O-CB 3.44Å; H79-E83 PolarHBondContact O-N 2.89Å; E83-Q87 WeakPolarHBondContact O-CG 3.42Å; E83-F117 HydrophobicContact CB-CE1 4.19Å; E83-F117 HydrophobicContact CB-CZ 4.35Å; E83-F117 WeakPolarHBondContact OE2-CE1 3.36Å
84I98.6Very high97.7Very high0 Ų055.5 Ų55.50%026%0.263CS..Iπ-helixtrans-70.9-48.6-175.9-61.9169.7000111H79 V80 Q87 L88 M105 F117 A121 I122 V125H79-I84 PolarHBondContact O-N 3.07Å; V80-I84 HydrophobicContact CG2-CD1 4.31Å; I84-Q87 PolarHBondContact O-N 3.14Å; I84-L88 HydrophobicContact CG2-CD1 3.65Å; I84-L88 HydrophobicContact CG2-CG 4.18Å; I84-L88 PolarHBondContact O-N 3.07Å; I84-M105 HydrophobicContact CG2-CG 4.18Å; I84-M105 HydrophobicContact CG2-SD 3.88Å; I84-F117 HydrophobicContact CD1-CB 4.38Å; I84-F117 HydrophobicContact CD1-CD2 3.95Å; I84-F117 HydrophobicContact CD1-CG 4.25Å; I84-F117 HydrophobicContact CG1-CD2 4Å; I84-F117 HydrophobicContact CG1-CE2 4.05Å; I84-A121 HydrophobicContact CD1-CB 4.21Å; I84-I122 HydrophobicContact CD1-CG1 4.46Å; I84-V125 HydrophobicContact CG2-CG1 4.4Å; I84-V125 HydrophobicContact CG2-CG2 4.13Å
85A98.6Very high97.7Very high4 Ų451.8 Ų51.83%0.03325%0.246CC..Hα-helixtrans-60.1-50.5-174.600000113.5I17 V80 Q87 L88 I89I17-A85 HydrophobicContact CB-CB 3.65Å; I17-A85 HydrophobicContact CG2-CB 3.97Å; V80-A85 WeakPolarHBondContact O-CB 3.48Å; V80-A85 PolarHBondContact O-N 3.48Å; A85-Q87 VanDerWaalsContact C-N 3.33Å; A85-Q87 PolarHBondContact O-N 2.75Å; A85-L88 PolarHBondContact O-N 2.89Å; A85-I89 WeakPolarHBondContact O-CD1 3.47Å; A85-I89 VanDerWaalsContact O-CG1 3.25Å; A85-I89 WeakPolarHBondContact O-CG1 3.27Å; A85-I89 PolarHBondContact O-N 2.79Å; A85-I89 VanDerWaalsContact O-N 3.12Å
86P98.4Very high97.6Very high68 Ų6849.2 Ų49.244%0.44224%0.239SC..Hα-helixtrans-60.5-42.3179.3-2435.6000112.6I89 E90P86-I89 PolarHBondContact O-N 3Å; P86-E90 WeakPolarHBondContact O-CB 3.29Å; P86-E90 PolarHBondContact O-N 3.23Å
87Q98.1Very high97.6Very high74 Ų7451.7 Ų51.735%0.34625%0.25SS..Hα-helixtrans-63.7-46.9-179.4-69.9-80-6.900111.7E83 I84 A85 I89 E90 K91 F104 L108E83-Q87 WeakPolarHBondContact O-CG 3.42Å; I84-Q87 PolarHBondContact O-N 3.14Å; A85-Q87 VanDerWaalsContact C-N 3.33Å; A85-Q87 PolarHBondContact O-N 2.75Å; Q87-I89 PolarHBondContact O-N 3.31Å; Q87-E90 PolarHBondContact O-N 2.91Å; Q87-K91 WeakPolarHBondContact O-CG 3.33Å; Q87-K91 PolarHBondContact O-N 3.24Å; Q87-F104 HydrophobicContact CB-CE1 3.87Å; Q87-F104 HydrophobicContact CB-CZ 3.97Å; Q87-L108 HydrophobicContact CB-CD2 4.09Å; Q87-L108 HydrophobicContact CG-CD1 4.27Å; Q87-L108 HydrophobicContact CG-CD2 4.01Å
88L97.4Very high97.6Very high1 Ų151.6 Ų51.61%0.00525%0.25CC..Hα-helixtrans-65.3-39.7179.1-75.7178.9000113I14 I17 I84 A85 E90 K91 K92 F93 I101 F104 M105 V125I14-L88 HydrophobicContact CD1-CB 4.35Å; I17-L88 HydrophobicContact CD1-CB 4.14Å; I17-L88 HydrophobicContact CD1-CD1 3.79Å; I84-L88 HydrophobicContact CG2-CD1 3.65Å; I84-L88 HydrophobicContact CG2-CG 4.18Å; I84-L88 PolarHBondContact O-N 3.07Å; A85-L88 PolarHBondContact O-N 2.89Å; L88-E90 VanDerWaalsContact C-N 3.35Å; L88-K91 PolarHBondContact O-N 3.22Å; L88-K92 PolarHBondContact O-N 2.98Å; L88-F93 HydrophobicContact CD2-CD2 4.28Å; L88-I101 HydrophobicContact CD1-CG2 4.35Å; L88-I101 HydrophobicContact CD2-CG2 3.9Å; L88-F104 HydrophobicContact CD2-CD1 3.52Å; L88-F104 HydrophobicContact CD2-CE1 3.95Å; L88-F104 HydrophobicContact CG-CD1 4.4Å; L88-F104 HydrophobicContact CG-CE1 4.44Å; L88-M105 HydrophobicContact CD1-CG 4.19Å; L88-M105 HydrophobicContact CD1-SD 3.96Å; L88-M105 HydrophobicContact CD2-CG 4.34Å; L88-V125 HydrophobicContact CD1-CG1 3.58Å
89I97.1Very high97.6Very high59 Ų5955.4 Ų55.430%0.30327%0.266SS..Hα-helixtrans-64.3-42.4176.7-67.1165.9000110.1I14 A85 P86 Q87 K91 K92I14-I89 HydrophobicContact CG2-CG1 4Å; A85-I89 WeakPolarHBondContact O-CD1 3.47Å; A85-I89 VanDerWaalsContact O-CG1 3.25Å; A85-I89 WeakPolarHBondContact O-CG1 3.27Å; A85-I89 PolarHBondContact O-N 2.79Å; A85-I89 VanDerWaalsContact O-N 3.12Å; P86-I89 PolarHBondContact O-N 3Å; Q87-I89 PolarHBondContact O-N 3.31Å; I89-K91 PolarHBondContact O-N 2.95Å; I89-K92 WeakPolarHBondContact O-CG 3.5Å; I89-K92 PolarHBondContact O-N 3.49Å
90E96.6Very high97.5Very high141 Ų14157.9 Ų57.966%0.65928%0.276SS*.Hα-helixtrans-63-40.1178.2-173.8-179.8175.900112.4P86 Q87 L88 K92P86-E90 WeakPolarHBondContact O-CB 3.29Å; P86-E90 PolarHBondContact O-N 3.23Å; Q87-E90 PolarHBondContact O-N 2.91Å; L88-E90 VanDerWaalsContact C-N 3.35Å; E90-K92 PolarHBondContact O-N 3.39Å
91K95.4Very high97.5Very high98 Ų9857.9 Ų57.943%0.42628%0.276SS..Hα-helixtrans-65.7-21.9178.4-69-56.4-178-167.30114Q87 L88 I89 F93 F104Q87-K91 WeakPolarHBondContact O-CG 3.33Å; Q87-K91 PolarHBondContact O-N 3.24Å; L88-K91 PolarHBondContact O-N 3.22Å; I89-K91 PolarHBondContact O-N 2.95Å; K91-F93 HydrophobicContact CB-CD1 4Å; K91-F93 HydrophobicContact CB-CD2 3.79Å; K91-F93 HydrophobicContact CB-CE1 3.79Å; K91-F93 HydrophobicContact CB-CE2 3.59Å; K91-F93 HydrophobicContact CB-CG 4.01Å; K91-F93 HydrophobicContact CB-CZ 3.6Å; K91-F93 HydrophobicContact CD-CZ 4.13Å; K91-F93 HydrophobicContact CG-CD2 4.44Å; K91-F93 HydrophobicContact CG-CE1 4.33Å; K91-F93 HydrophobicContact CG-CE2 3.79Å; K91-F93 HydrophobicContact CG-CZ 3.73Å; K91-F93 PolarHBondContact O-N 3.48Å; K91-F104 HydrophobicContact CD-CE2 4.24Å; K91-F104 HydrophobicContact CD-CZ 4.35Å; K91-F104 HydrophobicContact CG-CE1 4.12Å; K91-F104 HydrophobicContact CG-CE2 4.06Å; K91-F104 HydrophobicContact CG-CZ 3.81Å
92K94.2Very high97.5Very high158 Ų15855.8 Ų55.869%0.68727%0.265SS*.THydrogen-bonded Turntrans51.537.1-179.4-59.6176.4-177.5177.80113L88 I89 E90L88-K92 PolarHBondContact O-N 2.98Å; I89-K92 WeakPolarHBondContact O-CG 3.5Å; I89-K92 PolarHBondContact O-N 3.49Å; E90-K92 PolarHBondContact O-N 3.39Å
93F95.1Very high97.5Very high25 Ų2555 Ų5511%0.1126%0.261CS..  trans-62.4147.3172.6-62.3-35.3000110.3L88 K91 K100 I101 F104L88-F93 HydrophobicContact CD2-CD2 4.28Å; K91-F93 HydrophobicContact CB-CD1 4Å; K91-F93 HydrophobicContact CB-CD2 3.79Å; K91-F93 HydrophobicContact CB-CE1 3.79Å; K91-F93 HydrophobicContact CB-CE2 3.59Å; K91-F93 HydrophobicContact CB-CG 4.01Å; K91-F93 HydrophobicContact CB-CZ 3.6Å; K91-F93 HydrophobicContact CD-CZ 4.13Å; K91-F93 HydrophobicContact CG-CD2 4.44Å; K91-F93 HydrophobicContact CG-CE1 4.33Å; K91-F93 HydrophobicContact CG-CE2 3.79Å; K91-F93 HydrophobicContact CG-CZ 3.73Å; K91-F93 PolarHBondContact O-N 3.48Å; F93-K100 HydrophobicContact CD1-CD 3.9Å; F93-K100 HydrophobicContact CD1-CG 4.49Å; F93-K100 HydrophobicContact CE1-CD 4.01Å; F93-K100 VanDerWaalsContact CE1-CE 3.42Å; F93-K100 HydrophobicContact CE1-CG 4.32Å; F93-K100 HydrophobicContact CG-CD 4.41Å; F93-K100 HydrophobicContact CZ-CG 4.39Å; F93-I101 HydrophobicContact CB-CD1 4.01Å; F93-I101 HydrophobicContact CB-CG1 3.7Å; F93-I101 HydrophobicContact CD2-CG1 3.78Å; F93-I101 HydrophobicContact CG-CG1 4.13Å; F93-F104 HydrophobicContact CE2-CB 3.77Å; F93-F104 HydrophobicContact CE2-CD1 4.06Å; F93-F104 HydrophobicContact CE2-CD2 4.27Å; F93-F104 AromaticContact CE2-CG 3.75Å; F93-F104 HydrophobicContact CE2-CG 3.75Å; F93-F104 HydrophobicContact CZ-CB 4.41Å; F93-F104 HydrophobicContact CZ-CD2 4.45Å; F93-F104 HydrophobicContact CZ-CG 4.34Å
94S95.9Very high97.5Very high8 Ų852.7 Ų52.76%0.05625%0.25CS..BIsolated β-bridgetrans-78.2137.2169.7-175.60000109V96 E97 I101S94-V96 PolarHBondContact O-N 2.89Å; S94-E97 PolarHBondContact N-OE2 3.41Å; S94-E97 WeakPolarHBondContact O-CB 3.49Å; S94-E97 PolarHBondContact O-N 2.88Å; S94-I101 WeakPolarHBondContact O-CD1 3.48Å
95V97.4Very high97.5Very high0 Ų052.7 Ų52.70%025%0.25CS..THydrogen-bonded Turntrans-62.4-13.9-179.9-67.90000114.1I14 L35 T37 E97 A132 E136I14-V95 HydrophobicContact CD1-CG1 4.33Å; I14-V95 HydrophobicContact CG1-CG1 3.62Å; L35-V95 HydrophobicContact CD2-CG1 4.23Å; T37-V95 HydrophobicContact CG2-CG1 3.88Å; T37-V95 HydrophobicContact CG2-CG2 4.4Å; V95-E97 VanDerWaalsContact C-N 3.3Å; V95-A132 HydrophobicContact CB-CB 3.97Å; V95-A132 HydrophobicContact CG1-CB 3.97Å; V95-A132 HydrophobicContact CG2-CB 4.06Å; V95-E136 HydrophobicContact CG2-CB 3.85Å; V95-E136 HydrophobicContact CG2-CG 4.19Å
96V97.4Very high97.5Very high47 Ų4754.6 Ų54.629%0.28526%0.26SS..THydrogen-bonded Turntrans-79.4-12172.1-53.10000113.2S94 Q98 E136 K137S94-V96 PolarHBondContact O-N 2.89Å; V96-Q98 VanDerWaalsContact C-N 3.26Å; V96-Q98 PolarHBondContact O-N 3.28Å; V96-E136 HydrophobicContact CG1-CB 3.87Å; V96-E136 HydrophobicContact CG1-CG 3.73Å; V96-K137 HydrophobicContact CG1-CG 3.95Å
97E97.7Very high97.5Very high53 Ų5357.2 Ų57.225%0.24827%0.266CS..  trans-87.153.8178.1-59.5178.5105.600111S94 V95 E99 K100 I101S94-E97 PolarHBondContact N-OE2 3.41Å; S94-E97 WeakPolarHBondContact O-CB 3.49Å; S94-E97 PolarHBondContact O-N 2.88Å; V95-E97 VanDerWaalsContact C-N 3.3Å; E97-E99 PolarHBondContact O-N 2.89Å; E97-K100 HydrophobicContact CB-CB 3.94Å; E97-K100 HydrophobicContact CB-CD 4.15Å; E97-K100 HydrophobicContact CG-CD 4.45Å; E97-K100 WeakPolarHBondContact O-CB 3.4Å; E97-K100 PolarHBondContact O-N 3.17Å; E97-K100 WeakPolarHBondContact OE1-CD 3.31Å; E97-K100 IonicContact OE1-NZ 2.93Å; E97-K100 PolarHBondContact OE1-NZ 3.41Å; E97-K100 IonicContact OE2-NZ 3.72Å; E97-K100 PolarHBondContact OE2-NZ 3.48Å; E97-I101 PolarHBondContact O-N 3.03Å
98Q98.7Very high97.5Very high2 Ų255.6 Ų55.61%0.00926%0.259CS..Hα-helixtrans-48.4-52.4-175.1-175.470.344.800112.7V96 K100 I101 D102 S126 C130 L148 V361V96-Q98 VanDerWaalsContact C-N 3.26Å; V96-Q98 PolarHBondContact O-N 3.28Å; Q98-K100 VanDerWaalsContact C-N 3.28Å; Q98-K100 PolarHBondContact O-N 2.99Å; Q98-I101 PolarHBondContact O-N 3.15Å; Q98-D102 VanDerWaalsContact NE2-CG 3.33Å; Q98-D102 PolarHBondContact NE2-OD1 2.99Å; Q98-D102 VanDerWaalsContact NE2-OD1 3.16Å; Q98-D102 PolarHBondContact NE2-OD2 3.31Å; Q98-D102 WeakPolarHBondContact O-CB 3.4Å; Q98-D102 PolarHBondContact O-N 2.82Å; Q98-S126 PolarHBondContact NE2-O 3.32Å; Q98-S126 VanDerWaalsContact NE2-O 3.1Å; Q98-S126 PolarHBondContact NE2-OG 3.14Å; Q98-S126 VanDerWaalsContact NE2-OG 3.16Å; Q98-C130 VanDerWaalsContact OE1-CB 3.24Å; Q98-L148 HydrophobicContact CB-CD1 3.94Å; Q98-L148 HydrophobicContact CB-CD2 3.89Å; Q98-L148 HydrophobicContact CG-CD1 4.05Å; Q98-V361 HydrophobicContact CG-CB 4.43Å; Q98-V361 HydrophobicContact CG-CG1 4.35Å
99E98.6Very high97.6Very high129 Ų12955.8 Ų55.860%0.60326%0.261SS*.Hα-helixtrans-58.7-39-178.9179.1176.8-176.300112.5E97 K103 T362E97-E99 PolarHBondContact O-N 2.89Å; E99-K103 WeakPolarHBondContact O-CB 3.47Å; E99-K103 PolarHBondContact O-N 2.82Å; E99-T362 WeakPolarHBondContact CA-OG1 3.28Å; E99-T362 HydrophobicContact CB-CG2 4.16Å; E99-T362 HydrophobicContact CG-CG2 4Å
100K98.3Very high97.6Very high91 Ų9156 Ų5640%0.39628%0.277SS..Hα-helixtrans-71-40.6-179.3-169.3-173.1-172.1-175.90111.6F93 E97 Q98 F104F93-K100 HydrophobicContact CD1-CD 3.9Å; F93-K100 HydrophobicContact CD1-CG 4.49Å; F93-K100 HydrophobicContact CE1-CD 4.01Å; F93-K100 VanDerWaalsContact CE1-CE 3.42Å; F93-K100 HydrophobicContact CE1-CG 4.32Å; F93-K100 HydrophobicContact CG-CD 4.41Å; F93-K100 HydrophobicContact CZ-CG 4.39Å; E97-K100 HydrophobicContact CB-CB 3.94Å; E97-K100 HydrophobicContact CB-CD 4.15Å; E97-K100 HydrophobicContact CG-CD 4.45Å; E97-K100 WeakPolarHBondContact O-CB 3.4Å; E97-K100 PolarHBondContact O-N 3.17Å; E97-K100 WeakPolarHBondContact OE1-CD 3.31Å; E97-K100 IonicContact OE1-NZ 2.93Å; E97-K100 PolarHBondContact OE1-NZ 3.41Å; E97-K100 IonicContact OE2-NZ 3.72Å; E97-K100 PolarHBondContact OE2-NZ 3.48Å; Q98-K100 VanDerWaalsContact C-N 3.28Å; Q98-K100 PolarHBondContact O-N 2.99Å; K100-F104 WeakPolarHBondContact O-CB 3.48Å; K100-F104 PolarHBondContact O-N 3.07Å
101I98.6Very high97.7Very high0 Ų051.7 Ų51.70%026%0.261CS..Hα-helixtrans-68.6-47.8178.2-69.7166.4000110.2I14 L88 F93 S94 E97 Q98 F104 M105 V129I14-I101 HydrophobicContact CD1-CD1 4.5Å; L88-I101 HydrophobicContact CD1-CG2 4.35Å; L88-I101 HydrophobicContact CD2-CG2 3.9Å; F93-I101 HydrophobicContact CB-CD1 4.01Å; F93-I101 HydrophobicContact CB-CG1 3.7Å; F93-I101 HydrophobicContact CD2-CG1 3.78Å; F93-I101 HydrophobicContact CG-CG1 4.13Å; S94-I101 WeakPolarHBondContact O-CD1 3.48Å; E97-I101 PolarHBondContact O-N 3.03Å; Q98-I101 PolarHBondContact O-N 3.15Å; I101-F104 PolarHBondContact O-N 3.24Å; I101-M105 HydrophobicContact CG2-CE 4.2Å; I101-M105 WeakPolarHBondContact O-CG 3.46Å; I101-M105 PolarHBondContact O-N 2.94Å; I101-V129 HydrophobicContact CB-CG1 4.42Å; I101-V129 HydrophobicContact CD1-CG1 3.54Å; I101-V129 HydrophobicContact CD1-CG2 4.47Å; I101-V129 HydrophobicContact CG2-CG1 4.23Å; I101-V129 HydrophobicContact CG2-CG2 3.99Å
102D98.8Very high97.6Very high0 Ų054.3 Ų54.30%027%0.274CS..Hα-helixtrans-59.9-51.1177-74.6-20.8000110.4Q98 F104 M105 L106 S126 T362Q98-D102 VanDerWaalsContact NE2-CG 3.33Å; Q98-D102 PolarHBondContact NE2-OD1 2.99Å; Q98-D102 VanDerWaalsContact NE2-OD1 3.16Å; Q98-D102 PolarHBondContact NE2-OD2 3.31Å; Q98-D102 WeakPolarHBondContact O-CB 3.4Å; Q98-D102 PolarHBondContact O-N 2.82Å; D102-F104 VanDerWaalsContact C-N 3.27Å; D102-F104 PolarHBondContact O-N 2.87Å; D102-M105 PolarHBondContact O-N 3.02Å; D102-M105 WeakPolarHBondContact OD1-CE 3.48Å; D102-L106 VanDerWaalsContact O-CG 3.29Å; D102-L106 WeakPolarHBondContact O-CG 3.22Å; D102-L106 PolarHBondContact O-N 3.26Å; D102-S126 VanDerWaalsContact CG-OG 3.22Å; D102-S126 WeakPolarHBondContact OD1-CB 3.46Å; D102-S126 PolarHBondContact OD1-OG 3.37Å; D102-S126 PolarHBondContact OD2-OG 3.2Å; D102-T362 WeakPolarHBondContact OD2-CB 3.02Å; D102-T362 PolarHBondContact OD2-N 2.74Å; D102-T362 PolarHBondContact OD2-OG1 3.14Å
103K98.6Very high97.6Very high121 Ų12150.1 Ų50.153%0.52626%0.259SS..Hα-helixtrans-54.8-42.5177-178.5174.5177174.60112.4E99 L106 E107E99-K103 WeakPolarHBondContact O-CB 3.47Å; E99-K103 PolarHBondContact O-N 2.82Å; K103-L106 PolarHBondContact O-N 2.97Å; K103-E107 WeakPolarHBondContact CE-OE1 3.29Å; K103-E107 HydrophobicContact CG-CG 4.49Å; K103-E107 WeakPolarHBondContact O-CG 3.25Å; K103-E107 PolarHBondContact O-N 3.26Å
104F98.7Very high97.7Very high27 Ų2749.1 Ų49.112%0.11826%0.255CS..Hα-helixtrans-63.8-41.3177176.5-101000112.6Q87 L88 K91 F93 K100 I101 D102 L106 E107 L108Q87-F104 HydrophobicContact CB-CE1 3.87Å; Q87-F104 HydrophobicContact CB-CZ 3.97Å; L88-F104 HydrophobicContact CD2-CD1 3.52Å; L88-F104 HydrophobicContact CD2-CE1 3.95Å; L88-F104 HydrophobicContact CG-CD1 4.4Å; L88-F104 HydrophobicContact CG-CE1 4.44Å; K91-F104 HydrophobicContact CD-CE2 4.24Å; K91-F104 HydrophobicContact CD-CZ 4.35Å; K91-F104 HydrophobicContact CG-CE1 4.12Å; K91-F104 HydrophobicContact CG-CE2 4.06Å; K91-F104 HydrophobicContact CG-CZ 3.81Å; F93-F104 HydrophobicContact CE2-CB 3.77Å; F93-F104 HydrophobicContact CE2-CD1 4.06Å; F93-F104 HydrophobicContact CE2-CD2 4.27Å; F93-F104 AromaticContact CE2-CG 3.75Å; F93-F104 HydrophobicContact CE2-CG 3.75Å; F93-F104 HydrophobicContact CZ-CB 4.41Å; F93-F104 HydrophobicContact CZ-CD2 4.45Å; F93-F104 HydrophobicContact CZ-CG 4.34Å; K100-F104 WeakPolarHBondContact O-CB 3.48Å; K100-F104 PolarHBondContact O-N 3.07Å; I101-F104 PolarHBondContact O-N 3.24Å; D102-F104 VanDerWaalsContact C-N 3.27Å; D102-F104 PolarHBondContact O-N 2.87Å; F104-L106 VanDerWaalsContact C-N 3.34Å; F104-E107 PolarHBondContact O-N 3.49Å; F104-L108 HydrophobicContact CE1-CD2 4.46Å; F104-L108 VanDerWaalsContact O-CB 3.32Å; F104-L108 WeakPolarHBondContact O-CB 3.46Å; F104-L108 PolarHBondContact O-N 3.12Å
105M98.7Very high97.7Very high0 Ų051 Ų510%027%0.268CS..Hα-helixtrans-65.2-38.7175.5-67.6-171-65.700112I84 L88 I101 D102 L108 D109 I122 V125I84-M105 HydrophobicContact CG2-CG 4.18Å; I84-M105 HydrophobicContact CG2-SD 3.88Å; L88-M105 HydrophobicContact CD1-CG 4.19Å; L88-M105 HydrophobicContact CD1-SD 3.96Å; L88-M105 HydrophobicContact CD2-CG 4.34Å; I101-M105 HydrophobicContact CG2-CE 4.2Å; I101-M105 WeakPolarHBondContact O-CG 3.46Å; I101-M105 PolarHBondContact O-N 2.94Å; D102-M105 PolarHBondContact O-N 3.02Å; D102-M105 WeakPolarHBondContact OD1-CE 3.48Å; M105-L108 PolarHBondContact O-N 2.93Å; M105-D109 PolarHBondContact O-N 3.25Å; M105-I122 HydrophobicContact CB-CG2 4.07Å; M105-I122 HydrophobicContact CE-CG2 3.95Å; M105-I122 HydrophobicContact SD-CG2 4.32Å; M105-V125 HydrophobicContact CE-CB 4.36Å; M105-V125 HydrophobicContact CE-CG1 4.26Å; M105-V125 HydrophobicContact SD-CB 3.75Å; M105-V125 HydrophobicContact SD-CG1 3.57Å; M105-V125 VanDerWaalsContact SD-CG1 3.57Å
106L98.6Very high97.7Very high45 Ų4555.4 Ų55.424%0.23629%0.287CS..Hα-helixtrans-63.1-43.3175-62.2175.7000111.9D102 K103 F104 L108 D109 G110 K114 E363D102-L106 VanDerWaalsContact O-CG 3.29Å; D102-L106 WeakPolarHBondContact O-CG 3.22Å; D102-L106 PolarHBondContact O-N 3.26Å; K103-L106 PolarHBondContact O-N 2.97Å; F104-L106 VanDerWaalsContact C-N 3.34Å; L106-L108 VanDerWaalsContact C-N 3.34Å; L106-D109 PolarHBondContact O-N 3.18Å; L106-G110 PolarHBondContact O-N 2.61Å; L106-K114 HydrophobicContact CD2-CD 4.29Å; L106-K114 HydrophobicContact CD2-CG 4.34Å; L106-E363 HydrophobicContact CD1-CG 4.19Å; L106-E363 WeakPolarHBondContact CD2-OE2 3.02Å
107E98.5Very high97.8Very high122 Ų12253.2 Ų53.257%0.5727%0.274SS*.Hα-helixtrans-66.1-35.9175.6-72.8171.5-17800112.2K103 F104 G110K103-E107 WeakPolarHBondContact CE-OE1 3.29Å; K103-E107 HydrophobicContact CG-CG 4.49Å; K103-E107 WeakPolarHBondContact O-CG 3.25Å; K103-E107 PolarHBondContact O-N 3.26Å; F104-E107 PolarHBondContact O-N 3.49Å; E107-G110 PolarHBondContact O-N 2.9Å
108L98.1Very high97.8Very high40 Ų4050.7 Ų50.721%0.20926%0.262CS..Hα-helixtrans-70.7-35.7178-172.768.6000112.4Q87 F104 M105 L106 K116 F117Q87-L108 HydrophobicContact CB-CD2 4.09Å; Q87-L108 HydrophobicContact CG-CD1 4.27Å; Q87-L108 HydrophobicContact CG-CD2 4.01Å; F104-L108 HydrophobicContact CE1-CD2 4.46Å; F104-L108 VanDerWaalsContact O-CB 3.32Å; F104-L108 WeakPolarHBondContact O-CB 3.46Å; F104-L108 PolarHBondContact O-N 3.12Å; M105-L108 PolarHBondContact O-N 2.93Å; L106-L108 VanDerWaalsContact C-N 3.34Å; L108-K116 PolarHBondContact O-NZ 3.16Å; L108-F117 HydrophobicContact CB-CE2 4.01Å; L108-F117 HydrophobicContact CD2-CE2 3.85Å; L108-F117 HydrophobicContact CD2-CZ 4.05Å; L108-F117 HydrophobicContact CG-CE2 3.65Å; L108-F117 HydrophobicContact CG-CZ 3.77Å
109D98.6Very high97.8Very high6 Ų650.7 Ų50.73%0.03226%0.263CS..Hα-helixtrans-66.9-52.1169.8180-80.9000110.4M105 L106 T111 K114 K116 F117 I122M105-D109 PolarHBondContact O-N 3.25Å; L106-D109 PolarHBondContact O-N 3.18Å; D109-T111 VanDerWaalsContact C-N 3.28Å; D109-T111 PolarHBondContact O-N 3.22Å; D109-T111 WeakPolarHBondContact OD1-CB 3.33Å; D109-T111 PolarHBondContact OD1-N 3.29Å; D109-T111 PolarHBondContact OD1-OG1 2.57Å; D109-K114 WeakPolarHBondContact OD1-CA 3.47Å; D109-K116 WeakPolarHBondContact O-CD 3.25Å; D109-K116 WeakPolarHBondContact OD2-CB 3.33Å; D109-K116 PolarHBondContact OD2-N 3.16Å; D109-F117 HydrophobicContact CB-CD2 3.68Å; D109-F117 HydrophobicContact CB-CE2 4.05Å; D109-F117 HydrophobicContact CB-CG 4.4Å; D109-F117 PolarHBondContact OD2-N 2.88Å; D109-I122 HydrophobicContact CB-CD1 3.91Å
110G98Very high97.8Very high63 Ų6344.7 Ų44.765%0.64924%0.235SC*.  trans75.47.6173.300000115.3L106 E107L106-G110 PolarHBondContact O-N 2.61Å; E107-G110 PolarHBondContact O-N 2.9Å
111T97.7Very high97.8Very high51 Ų5140.4 Ų40.431%0.31322%0.216SC..SBendtrans-113.1152.9178.474.80000111.7D109 N113 K114 S115 K116D109-T111 VanDerWaalsContact C-N 3.28Å; D109-T111 PolarHBondContact O-N 3.22Å; D109-T111 WeakPolarHBondContact OD1-CB 3.33Å; D109-T111 PolarHBondContact OD1-N 3.29Å; D109-T111 PolarHBondContact OD1-OG1 2.57Å; T111-N113 VanDerWaalsContact C-N 3.35Å; T111-N113 PolarHBondContact O-N 3.43Å; T111-K114 WeakPolarHBondContact OG1-CA 3.42Å; T111-K114 PolarHBondContact OG1-N 3.47Å; T111-K114 VanDerWaalsContact OG1-N 3.14Å; T111-S115 PolarHBondContact OG1-N 3.47Å; T111-S115 PolarHBondContact OG1-OG 3.43Å; T111-K116 HydrophobicContact CG2-CB 3.97Å
112E93.6Very high97.8Very high152 Ų15240.4 Ų40.471%0.7122%0.216SC*.THydrogen-bonded Turntrans-64.2-38.4-177.3-179.8168.7-159.400112.9K337E112-K337 IonicContact OE1-NZ 3.87Å; E112-K337 PolarHBondContact OE1-NZ 3.36Å
113N93.6Very high97.8Very high70 Ų7040.4 Ų40.437%0.37422%0.216SC..THydrogen-bonded Turntrans-107.418.2-175.267.3-23.1000113.3L58 T111 S115L58-N113 PolarHBondContact N-O 3.08Å; T111-N113 VanDerWaalsContact C-N 3.35Å; T111-N113 PolarHBondContact O-N 3.43Å; N113-S115 PolarHBondContact O-N 3.06Å; N113-S115 WeakPolarHBondContact OD1-CB 3.19Å; N113-S115 PolarHBondContact OD1-OG 3.02Å
114K97.8Very high97.8Very high5 Ų534.6 Ų34.62%0.02219%0.191CC..  trans59.132.1179.8-56169.3170.166.50113A57 L106 D109 T111 K116 G118 A119 I122 I358 E363A57-K114 HydrophobicContact CB-CD 4.16Å; L106-K114 HydrophobicContact CD2-CD 4.29Å; L106-K114 HydrophobicContact CD2-CG 4.34Å; D109-K114 WeakPolarHBondContact OD1-CA 3.47Å; T111-K114 WeakPolarHBondContact OG1-CA 3.42Å; T111-K114 PolarHBondContact OG1-N 3.47Å; T111-K114 VanDerWaalsContact OG1-N 3.14Å; K114-K116 VanDerWaalsContact C-N 3.34Å; K114-K116 PolarHBondContact O-N 3.5Å; K114-G118 CarbonylContact O-C 3.55Å; K114-G118 WeakPolarHBondContact O-CA 3.35Å; K114-G118 PolarHBondContact O-N 3Å; K114-A119 HydrophobicContact CB-CB 4.28Å; K114-A119 HydrophobicContact CD-CB 4.05Å; K114-I122 HydrophobicContact CB-CD1 3.99Å; K114-I122 HydrophobicContact CD-CD1 4.1Å; K114-I122 HydrophobicContact CG-CD1 3.9Å; K114-I358 WeakPolarHBondContact CD-O 3.49Å; K114-I358 WeakPolarHBondContact CE-O 3.31Å; K114-I358 PolarHBondContact NZ-O 2.7Å; K114-E363 WeakPolarHBondContact CE-OE2 3.39Å; K114-E363 IonicContact NZ-OE1 2.71Å; K114-E363 PolarHBondContact NZ-OE1 3.12Å; K114-E363 IonicContact NZ-OE2 3.79Å; K114-E363 PolarHBondContact NZ-OE2 3.19Å
115S96.6Very high97.8Very high46 Ų4633.3 Ų33.332%0.32219%0.185SC..THydrogen-bonded Turntrans-77.5-15.2-172.649.70000114.5T111 N113T111-S115 PolarHBondContact OG1-N 3.47Å; T111-S115 PolarHBondContact OG1-OG 3.43Å; N113-S115 PolarHBondContact O-N 3.06Å; N113-S115 WeakPolarHBondContact OD1-CB 3.19Å; N113-S115 PolarHBondContact OD1-OG 3.02Å
116K97.6Very high97.8Very high94 Ų9433.3 Ų33.341%0.40919%0.185SC..THydrogen-bonded Turntrans-73.8-51.1176.7180-172172.2-169.10111H79 L108 D109 T111 K114H79-K116 PolarHBondContact NE2-O 3.34Å; L108-K116 PolarHBondContact O-NZ 3.16Å; D109-K116 WeakPolarHBondContact O-CD 3.25Å; D109-K116 WeakPolarHBondContact OD2-CB 3.33Å; D109-K116 PolarHBondContact OD2-N 3.16Å; T111-K116 HydrophobicContact CG2-CB 3.97Å; K114-K116 VanDerWaalsContact C-N 3.34Å; K114-K116 PolarHBondContact O-N 3.5Å
117F98.1Very high97.8Very high0 Ų031.4 Ų31.40%018%0.175CC..THydrogen-bonded Turntrans-96.2-23.5-179.4-62.8-30.9000113.8L60 H79 E83 I84 L108 D109 A121 I122L60-F117 WeakPolarHBondContact CD2-O 3.21Å; H79-F117 HydrophobicContact CB-CB 4.31Å; H79-F117 HydrophobicContact CB-CD1 3.94Å; H79-F117 HydrophobicContact CB-CG 4.38Å; H79-F117 AromaticContact CG-CD1 3.8Å; H79-F117 AromaticContact ND1-CD1 3.74Å; E83-F117 HydrophobicContact CB-CE1 4.19Å; E83-F117 HydrophobicContact CB-CZ 4.35Å; E83-F117 WeakPolarHBondContact OE2-CE1 3.36Å; I84-F117 HydrophobicContact CD1-CB 4.38Å; I84-F117 HydrophobicContact CD1-CD2 3.95Å; I84-F117 HydrophobicContact CD1-CG 4.25Å; I84-F117 HydrophobicContact CG1-CD2 4Å; I84-F117 HydrophobicContact CG1-CE2 4.05Å; L108-F117 HydrophobicContact CB-CE2 4.01Å; L108-F117 HydrophobicContact CD2-CE2 3.85Å; L108-F117 HydrophobicContact CD2-CZ 4.05Å; L108-F117 HydrophobicContact CG-CE2 3.65Å; L108-F117 HydrophobicContact CG-CZ 3.77Å; D109-F117 HydrophobicContact CB-CD2 3.68Å; D109-F117 HydrophobicContact CB-CE2 4.05Å; D109-F117 HydrophobicContact CB-CG 4.4Å; D109-F117 PolarHBondContact OD2-N 2.88Å; F117-A121 HydrophobicContact CB-CB 4.23Å; F117-A121 VanDerWaalsContact O-CB 3.25Å; F117-A121 WeakPolarHBondContact O-CB 3.33Å; F117-I122 HydrophobicContact CB-CG1 4.32Å; F117-I122 HydrophobicContact CD2-CD1 4.5Å; F117-I122 HydrophobicContact CD2-CG1 4.47Å
118G98.1Very high97.9Very high0 Ų025.6 Ų25.60%015%0.148CC..  trans87.5135.8-16500000111.5L58 K114 N120 A121 I122L58-G118 CarbonylContact O-C 3.51Å; L58-G118 WeakPolarHBondContact O-CA 3.46Å; K114-G118 CarbonylContact O-C 3.55Å; K114-G118 WeakPolarHBondContact O-CA 3.35Å; K114-G118 PolarHBondContact O-N 3Å; G118-N120 WeakPolarHBondContact CA-OD1 3.42Å; G118-N120 PolarHBondContact O-N 2.98Å; G118-A121 WeakPolarHBondContact O-CB 3.45Å; G118-A121 PolarHBondContact O-N 3.38Å; G118-I122 PolarHBondContact O-N 2.9Å
119A98.1Very high97.9Very high3 Ų323.7 Ų23.73%0.02514%0.138CC..Hα-helixtrans-57.1-32.6172.500000111.8A57 L58 K114 I122 L123A57-A119 HydrophobicContact CB-CB 3.6Å; L58-A119 WeakPolarHBondContact O-CB 3.4Å; L58-A119 PolarHBondContact O-N 3.1Å; K114-A119 HydrophobicContact CB-CB 4.28Å; K114-A119 HydrophobicContact CD-CB 4.05Å; A119-I122 PolarHBondContact O-N 3.45Å; A119-L123 WeakPolarHBondContact O-CB 3.47Å; A119-L123 PolarHBondContact O-N 2.9Å
120N98.4Very high97.9Very high3 Ų323.4 Ų23.42%0.01614%0.136CC..Hα-helixtrans-67.3-30.8175.455.2-23.1000113.9V31 V46 E59 L60 G118 G124V31-N120 HydrophobicContact CG2-CB 4.26Å; V46-N120 HydrophobicContact CG1-CB 3.95Å; V46-N120 WeakPolarHBondContact CG2-O 3.41Å; E59-N120 HydrophobicContact CG-CB 4.24Å; L60-N120 PolarHBondContact N-OD1 3.36Å; L60-N120 PolarHBondContact O-ND2 3.03Å; G118-N120 WeakPolarHBondContact CA-OD1 3.42Å; G118-N120 PolarHBondContact O-N 2.98Å; N120-G124 PolarHBondContact O-N 3.05Å
121A98.8Very high98Very high0 Ų022.2 Ų22.20%011%0.113CC..Hα-helixtrans-70.4-50.1172.400000111.3A76 V80 I84 F117 G118A76-A121 HydrophobicContact CB-CB 4.26Å; V80-A121 HydrophobicContact CG2-CB 3.69Å; I84-A121 HydrophobicContact CD1-CB 4.21Å; F117-A121 HydrophobicContact CB-CB 4.23Å; F117-A121 VanDerWaalsContact O-CB 3.25Å; F117-A121 WeakPolarHBondContact O-CB 3.33Å; G118-A121 WeakPolarHBondContact O-CB 3.45Å; G118-A121 PolarHBondContact O-N 3.38Å
122I98.9Very high98Very high0 Ų019.8 Ų19.80%010%0.098CC..Hα-helixtrans-64.8-46-177.1-61.8177.1000110.7I84 M105 D109 K114 F117 G118 A119 G124 V125 S126 G359I84-I122 HydrophobicContact CD1-CG1 4.46Å; M105-I122 HydrophobicContact CB-CG2 4.07Å; M105-I122 HydrophobicContact CE-CG2 3.95Å; M105-I122 HydrophobicContact SD-CG2 4.32Å; D109-I122 HydrophobicContact CB-CD1 3.91Å; K114-I122 HydrophobicContact CB-CD1 3.99Å; K114-I122 HydrophobicContact CD-CD1 4.1Å; K114-I122 HydrophobicContact CG-CD1 3.9Å; F117-I122 HydrophobicContact CB-CG1 4.32Å; F117-I122 HydrophobicContact CD2-CD1 4.5Å; F117-I122 HydrophobicContact CD2-CG1 4.47Å; G118-I122 PolarHBondContact O-N 2.9Å; A119-I122 PolarHBondContact O-N 3.45Å; I122-G124 PolarHBondContact O-N 3.36Å; I122-V125 PolarHBondContact O-N 3.26Å; I122-S126 WeakPolarHBondContact O-CB 3.34Å; I122-S126 PolarHBondContact O-N 2.72Å; I122-G359 WeakPolarHBondContact CG2-O 3.33Å
123L98.9Very high98.2Very high0 Ų012.5 Ų12.50%06%0.064CC..Hα-helixtrans-63.1-43.4-176.5-175.967.5000111.9V46 A119 V125 S126 L127 V355 N356 G359V46-L123 HydrophobicContact CG1-CD2 3.87Å; V46-L123 HydrophobicContact CG2-CB 4.19Å; V46-L123 HydrophobicContact CG2-CD2 4.21Å; V46-L123 HydrophobicContact CG2-CG 4.29Å; A119-L123 WeakPolarHBondContact O-CB 3.47Å; A119-L123 PolarHBondContact O-N 2.9Å; L123-V125 VanDerWaalsContact C-N 3.26Å; L123-V125 PolarHBondContact O-N 3.04Å; L123-S126 WeakPolarHBondContact O-CB 3.25Å; L123-S126 PolarHBondContact O-N 3.43Å; L123-S126 VanDerWaalsContact O-N 3.09Å; L123-L127 HydrophobicContact CD1-CD1 4.24Å; L123-L127 HydrophobicContact CD1-CD2 4.19Å; L123-L127 HydrophobicContact CD1-CG 3.97Å; L123-L127 HydrophobicContact CD2-CD1 4.25Å; L123-L127 HydrophobicContact CG-CD1 3.8Å; L123-L127 HydrophobicContact CG-CG 4Å; L123-L127 WeakPolarHBondContact O-CB 3.47Å; L123-L127 VanDerWaalsContact O-CG 3.23Å; L123-L127 WeakPolarHBondContact O-CG 3.33Å; L123-L127 PolarHBondContact O-N 2.96Å; L123-V355 HydrophobicContact CD1-CB 4.17Å; L123-V355 HydrophobicContact CD1-CG2 4.38Å; L123-V355 HydrophobicContact CD2-CG2 4.13Å; L123-N356 VanDerWaalsContact CD2-CA 3.47Å; L123-N356 HydrophobicContact CD2-CB 3.42Å; L123-N356 VanDerWaalsContact CD2-CB 3.42Å; L123-G359 WeakPolarHBondContact CA-O 3.2Å; L123-G359 PolarHBondContact N-O 2.95Å
124G98.8Very high98.5Very high0 Ų09.4 Ų9.40%05%0.048CC..Hα-helixtrans-56.7-43.1179.600000112N120 I122 A128N120-G124 PolarHBondContact O-N 3.05Å; I122-G124 PolarHBondContact O-N 3.36Å; G124-A128 WeakPolarHBondContact O-CB 3.11Å; G124-A128 PolarHBondContact O-N 2.99Å; G124-A128 VanDerWaalsContact O-N 3.17Å
125V98.9Very high98.5Very high0 Ų010.7 Ų10.70%06%0.06CC..Hα-helixtrans-67.4-46.3174.8-178.70000111I17 V33 V80 I84 L88 M105 I122 L123 L127 A128 V129I17-V125 HydrophobicContact CD1-CG1 4.15Å; I17-V125 HydrophobicContact CG2-CG2 4.38Å; V33-V125 HydrophobicContact CG1-CG2 4.07Å; V33-V125 HydrophobicContact CG2-CG2 4.23Å; V80-V125 HydrophobicContact CG1-CG2 3.7Å; V80-V125 HydrophobicContact CG2-CG2 4.2Å; I84-V125 HydrophobicContact CG2-CG1 4.4Å; I84-V125 HydrophobicContact CG2-CG2 4.13Å; L88-V125 HydrophobicContact CD1-CG1 3.58Å; M105-V125 HydrophobicContact CE-CB 4.36Å; M105-V125 HydrophobicContact CE-CG1 4.26Å; M105-V125 HydrophobicContact SD-CB 3.75Å; M105-V125 HydrophobicContact SD-CG1 3.57Å; M105-V125 VanDerWaalsContact SD-CG1 3.57Å; I122-V125 PolarHBondContact O-N 3.26Å; L123-V125 VanDerWaalsContact C-N 3.26Å; L123-V125 PolarHBondContact O-N 3.04Å; V125-L127 VanDerWaalsContact C-N 3.33Å; V125-L127 PolarHBondContact O-N 3.41Å; V125-A128 PolarHBondContact O-N 3.38Å; V125-V129 HydrophobicContact CG1-CG2 4.14Å; V125-V129 WeakPolarHBondContact O-CB 3.33Å; V125-V129 VanDerWaalsContact O-CG2 3.22Å; V125-V129 WeakPolarHBondContact O-CG2 3.49Å; V125-V129 PolarHBondContact O-N 2.86Å
126S98.9Very high98.6Very high0 Ų010.7 Ų10.70%06%0.055CC..Hα-helixtrans-55.5-44.8179.8-171.80000112.6Q98 D102 I122 L123 C130 V361Q98-S126 PolarHBondContact NE2-O 3.32Å; Q98-S126 VanDerWaalsContact NE2-O 3.1Å; Q98-S126 PolarHBondContact NE2-OG 3.14Å; Q98-S126 VanDerWaalsContact NE2-OG 3.16Å; D102-S126 VanDerWaalsContact CG-OG 3.22Å; D102-S126 WeakPolarHBondContact OD1-CB 3.46Å; D102-S126 PolarHBondContact OD1-OG 3.37Å; D102-S126 PolarHBondContact OD2-OG 3.2Å; I122-S126 WeakPolarHBondContact O-CB 3.34Å; I122-S126 PolarHBondContact O-N 2.72Å; L123-S126 WeakPolarHBondContact O-CB 3.25Å; L123-S126 PolarHBondContact O-N 3.43Å; L123-S126 VanDerWaalsContact O-N 3.09Å; S126-C130 PolarHBondContact O-N 2.98Å; S126-C130 VanDerWaalsContact O-N 3.07Å; S126-V361 WeakPolarHBondContact OG-CG2 3.34Å; S126-V361 PolarHBondContact OG-N 3.1Å
127L98.9Very high98.6Very high4 Ų410.2 Ų10.22%0.0215%0.053CC..Hα-helixtrans-67.6-43.9177.4-63.7173.1000111.9A44 L123 V125 V129 C130 K131 V361 F391A44-L127 HydrophobicContact CB-CB 3.38Å; A44-L127 HydrophobicContact CB-CD1 4.29Å; A44-L127 HydrophobicContact CB-CG 4.49Å; L123-L127 HydrophobicContact CD1-CD1 4.24Å; L123-L127 HydrophobicContact CD1-CD2 4.19Å; L123-L127 HydrophobicContact CD1-CG 3.97Å; L123-L127 HydrophobicContact CD2-CD1 4.25Å; L123-L127 HydrophobicContact CG-CD1 3.8Å; L123-L127 HydrophobicContact CG-CG 4Å; L123-L127 WeakPolarHBondContact O-CB 3.47Å; L123-L127 VanDerWaalsContact O-CG 3.23Å; L123-L127 WeakPolarHBondContact O-CG 3.33Å; L123-L127 PolarHBondContact O-N 2.96Å; V125-L127 VanDerWaalsContact C-N 3.33Å; V125-L127 PolarHBondContact O-N 3.41Å; L127-V129 VanDerWaalsContact C-N 3.33Å; L127-V129 PolarHBondContact O-N 2.92Å; L127-C130 WeakPolarHBondContact O-CB 3.35Å; L127-C130 PolarHBondContact O-N 3.3Å; L127-K131 WeakPolarHBondContact O-CG 2.95Å; L127-K131 PolarHBondContact O-N 3.38Å; L127-V361 HydrophobicContact CD2-CG2 3.68Å; L127-V361 HydrophobicContact CG-CG2 4.43Å; L127-F391 HydrophobicContact CB-CD2 4.39Å; L127-F391 HydrophobicContact CB-CE2 4.45Å; L127-F391 HydrophobicContact CD2-CB 4.49Å; L127-F391 HydrophobicContact CD2-CD1 3.41Å; L127-F391 VanDerWaalsContact CD2-CD1 3.41Å; L127-F391 HydrophobicContact CD2-CD2 3.7Å; L127-F391 HydrophobicContact CD2-CE1 3.33Å; L127-F391 HydrophobicContact CD2-CE2 3.64Å; L127-F391 HydrophobicContact CD2-CG 3.6Å; L127-F391 HydrophobicContact CD2-CZ 3.47Å; L127-F391 VanDerWaalsContact CD2-CZ 3.47Å
128A98.9Very high98.6Very high0 Ų013.4 Ų13.40%09%0.086CC..Hα-helixtrans-65.4-36.9178.400000112V33 L35 A44 G124 V125 K131 A132V33-A128 HydrophobicContact CG1-CB 4.24Å; L35-A128 HydrophobicContact CB-CB 3.86Å; A44-A128 HydrophobicContact CB-CB 4.15Å; G124-A128 WeakPolarHBondContact O-CB 3.11Å; G124-A128 PolarHBondContact O-N 2.99Å; G124-A128 VanDerWaalsContact O-N 3.17Å; V125-A128 PolarHBondContact O-N 3.38Å; A128-K131 PolarHBondContact O-N 2.92Å; A128-A132 WeakPolarHBondContact O-CB 3.31Å; A128-A132 PolarHBondContact O-N 3.02Å
129V98.9Very high98.6Very high0 Ų015.6 Ų15.60%010%0.099CC..Hα-helixtrans-61-47171.4169.10000110.5I14 L35 I101 V125 L127 K131 A132 G133I14-V129 HydrophobicContact CD1-CG2 4.46Å; L35-V129 HydrophobicContact CD1-CB 4.39Å; L35-V129 HydrophobicContact CD1-CG2 3.45Å; L35-V129 VanDerWaalsContact CD1-CG2 3.45Å; I101-V129 HydrophobicContact CB-CG1 4.42Å; I101-V129 HydrophobicContact CD1-CG1 3.54Å; I101-V129 HydrophobicContact CD1-CG2 4.47Å; I101-V129 HydrophobicContact CG2-CG1 4.23Å; I101-V129 HydrophobicContact CG2-CG2 3.99Å; V125-V129 HydrophobicContact CG1-CG2 4.14Å; V125-V129 WeakPolarHBondContact O-CB 3.33Å; V125-V129 VanDerWaalsContact O-CG2 3.22Å; V125-V129 WeakPolarHBondContact O-CG2 3.49Å; V125-V129 PolarHBondContact O-N 2.86Å; L127-V129 VanDerWaalsContact C-N 3.33Å; L127-V129 PolarHBondContact O-N 2.92Å; V129-K131 VanDerWaalsContact C-N 3.34Å; V129-K131 PolarHBondContact O-N 3.27Å; V129-A132 CarbonylContact O-C 3.55Å; V129-A132 WeakPolarHBondContact O-CB 3.46Å; V129-A132 PolarHBondContact O-N 2.74Å; V129-A132 VanDerWaalsContact O-N 3.15Å; V129-G133 PolarHBondContact O-N 3.12Å
130C98.9Very high98.6Very high0 Ų017.3 Ų17.30%011%0.11CC..Hα-helixtrans-60.8-42.9179.7-168.50000111.9Q98 S126 L127 G133 A134 H144 V361 F391Q98-C130 VanDerWaalsContact OE1-CB 3.24Å; S126-C130 PolarHBondContact O-N 2.98Å; S126-C130 VanDerWaalsContact O-N 3.07Å; L127-C130 WeakPolarHBondContact O-CB 3.35Å; L127-C130 PolarHBondContact O-N 3.3Å; C130-G133 PolarHBondContact O-N 2.93Å; C130-A134 PolarHBondContact O-N 2.68Å; C130-H144 PolarHBondContact O-CD2 3.46Å; C130-H144 VanDerWaalsContact O-CD2 3.28Å; C130-V361 HydrophobicContact CB-CG2 4.36Å; C130-F391 HydrophobicContact CB-CE2 3.95Å; C130-F391 HydrophobicContact CB-CZ 4.29Å
131K98.9Very high98.6Very high38 Ų3818.2 Ų18.217%0.16512%0.115CC..Hα-helixtrans-60-45.2173.2-72.3174.9177.5178.70112.1F42 R43 A44 L127 A128 V129 G133 A134 A135 L141 D389F42-K131 HydrophobicContact CB-CB 4.13Å; F42-K131 HydrophobicContact CD1-CB 4.27Å; R43-K131 WeakPolarHBondContact O-CD 3.33Å; R43-K131 WeakPolarHBondContact O-CE 3.44Å; R43-K131 PolarHBondContact O-NZ 3.04Å; A44-K131 HydrophobicContact CB-CD 4.4Å; L127-K131 WeakPolarHBondContact O-CG 2.95Å; L127-K131 PolarHBondContact O-N 3.38Å; A128-K131 PolarHBondContact O-N 2.92Å; V129-K131 VanDerWaalsContact C-N 3.34Å; V129-K131 PolarHBondContact O-N 3.27Å; K131-G133 VanDerWaalsContact C-N 3.34Å; K131-A134 PolarHBondContact O-N 3.02Å; K131-A135 PolarHBondContact O-N 3.22Å; K131-L141 HydrophobicContact CG-CD1 4.37Å; K131-L141 HydrophobicContact CG-CD2 4Å; K131-D389 IonicContact NZ-OD1 3.67Å; K131-D389 PolarHBondContact NZ-OD1 2.87Å; K131-D389 IonicContact NZ-OD2 3.43Å; K131-D389 PolarHBondContact NZ-OD2 3.25Å
132A98.8Very high98.6Very high0 Ų019 Ų190%012%0.118CC..Hα-helixtrans-65-37.9175.800000112.4L35 T37 F42 V95 A128 V129 A134 A135 E136L35-A132 HydrophobicContact CD2-CB 3.78Å; T37-A132 HydrophobicContact CG2-CB 4.11Å; F42-A132 HydrophobicContact CB-CB 4.17Å; F42-A132 HydrophobicContact CD1-CB 4.29Å; F42-A132 HydrophobicContact CD2-CB 3.38Å; F42-A132 HydrophobicContact CE2-CB 3.82Å; F42-A132 HydrophobicContact CG-CB 3.64Å; F42-A132 HydrophobicContact CZ-CB 4.44Å; V95-A132 HydrophobicContact CB-CB 3.97Å; V95-A132 HydrophobicContact CG1-CB 3.97Å; V95-A132 HydrophobicContact CG2-CB 4.06Å; A128-A132 WeakPolarHBondContact O-CB 3.31Å; A128-A132 PolarHBondContact O-N 3.02Å; V129-A132 CarbonylContact O-C 3.55Å; V129-A132 WeakPolarHBondContact O-CB 3.46Å; V129-A132 PolarHBondContact O-N 2.74Å; V129-A132 VanDerWaalsContact O-N 3.15Å; A132-A134 VanDerWaalsContact C-N 3.33Å; A132-A134 PolarHBondContact O-N 3.17Å; A132-A135 PolarHBondContact O-N 3.42Å; A132-E136 WeakPolarHBondContact O-CB 3.49Å; A132-E136 PolarHBondContact O-N 2.88Å
133G98.6Very high98.6Very high0 Ų021.5 Ų21.50%013%0.127CC..Hα-helixtrans-62-37.717600000113V129 C130 K131 K137V129-G133 PolarHBondContact O-N 3.12Å; C130-G133 PolarHBondContact O-N 2.93Å; K131-G133 VanDerWaalsContact C-N 3.34Å; G133-K137 PolarHBondContact O-N 3.39Å; G133-K137 VanDerWaalsContact O-N 3.16Å
134A98.7Very high98.6Very high4 Ų421.5 Ų21.53%0.03313%0.127CC..Hα-helixtrans-63.4-48.6173.400000111.9C130 K131 A132 E136 K137 G138 V139 L141 H144C130-A134 PolarHBondContact O-N 2.68Å; K131-A134 PolarHBondContact O-N 3.02Å; A132-A134 VanDerWaalsContact C-N 3.33Å; A132-A134 PolarHBondContact O-N 3.17Å; A134-E136 VanDerWaalsContact C-N 3.35Å; A134-E136 PolarHBondContact O-N 2.89Å; A134-K137 CarbonylContact O-C 3.5Å; A134-K137 PolarHBondContact O-N 3.41Å; A134-G138 PolarHBondContact O-N 3.03Å; A134-V139 CarbonylContact C-O 3.54Å; A134-V139 PolarHBondContact O-N 3.39Å; A134-V139 VanDerWaalsContact O-N 3.09Å; A134-L141 HydrophobicContact CB-CB 4.36Å; A134-L141 HydrophobicContact CB-CD1 4.16Å; A134-H144 HydrophobicContact CB-CB 3.52Å
135A98.4Very high98.6Very high33 Ų3321.5 Ų21.527%0.27313%0.127SC..Hα-helixtrans-67.4-32.8178.700000113.5F42 K131 A132 K137 G138F42-A135 HydrophobicContact CD1-CB 4.38Å; F42-A135 HydrophobicContact CE1-CB 3.24Å; F42-A135 HydrophobicContact CZ-CB 3.38Å; K131-A135 PolarHBondContact O-N 3.22Å; A132-A135 PolarHBondContact O-N 3.42Å; A135-K137 VanDerWaalsContact C-N 3.33Å; A135-G138 PolarHBondContact O-N 3.39Å; A135-G138 VanDerWaalsContact O-N 3.14Å
136E97.7Very high98.6Very high46 Ų4621.5 Ų21.522%0.21513%0.127CC..Hα-helixtrans-61.9-42.5172.9-175.264-170.900111.2M12 V95 V96 A132 A134 G138M12-E136 WeakPolarHBondContact CB-OE1 3.36Å; M12-E136 WeakPolarHBondContact CE-OE2 3.42Å; M12-E136 WeakPolarHBondContact CG-OE1 2.99Å; V95-E136 HydrophobicContact CG2-CB 3.85Å; V95-E136 HydrophobicContact CG2-CG 4.19Å; V96-E136 HydrophobicContact CG1-CB 3.87Å; V96-E136 HydrophobicContact CG1-CG 3.73Å; A132-E136 WeakPolarHBondContact O-CB 3.49Å; A132-E136 PolarHBondContact O-N 2.88Å; A134-E136 VanDerWaalsContact C-N 3.35Å; A134-E136 PolarHBondContact O-N 2.89Å; E136-G138 VanDerWaalsContact C-N 3.26Å; E136-G138 PolarHBondContact O-N 3.47Å
137K97.5Very high98.6Very high84 Ų8424.9 Ų24.937%0.36515%0.145SC..Hα-helixtrans-74.4-13.8174.1-72.1-170.7-175.7175.60113.7V96 G133 A134 A135 V139 H144 D147V96-K137 HydrophobicContact CG1-CG 3.95Å; G133-K137 PolarHBondContact O-N 3.39Å; G133-K137 VanDerWaalsContact O-N 3.16Å; A134-K137 CarbonylContact O-C 3.5Å; A134-K137 PolarHBondContact O-N 3.41Å; A135-K137 VanDerWaalsContact C-N 3.33Å; K137-V139 VanDerWaalsContact C-N 3.35Å; K137-V139 HydrophobicContact CB-CG1 4.48Å; K137-V139 HydrophobicContact CB-CG2 3.88Å; K137-V139 HydrophobicContact CD-CG2 4.45Å; K137-H144 WeakPolarHBondContact CD-ND1 3.14Å; K137-H144 WeakPolarHBondContact CE-ND1 3.36Å; K137-H144 PolarHBondContact NZ-ND1 3.03Å; K137-D147 IonicContact NZ-OD2 3.67Å; K137-D147 PolarHBondContact NZ-OD2 2.7Å
138G97.8Very high98.6Very high67 Ų6726.9 Ų26.969%0.69116%0.156SC*.THydrogen-bonded Turntrans67.533.1-17500000113.4A134 A135 E136A134-G138 PolarHBondContact O-N 3.03Å; A135-G138 PolarHBondContact O-N 3.39Å; A135-G138 VanDerWaalsContact O-N 3.14Å; E136-G138 VanDerWaalsContact C-N 3.26Å; E136-G138 PolarHBondContact O-N 3.47Å
139V98.6Very high98.5Very high46 Ų4627.2 Ų27.228%0.27916%0.158SC..SBendtrans-124.6157.7179.1-59.50000111A134 K137 R143 H144A134-V139 CarbonylContact C-O 3.54Å; A134-V139 PolarHBondContact O-N 3.39Å; A134-V139 VanDerWaalsContact O-N 3.09Å; K137-V139 VanDerWaalsContact C-N 3.35Å; K137-V139 HydrophobicContact CB-CG1 4.48Å; K137-V139 HydrophobicContact CB-CG2 3.88Å; K137-V139 HydrophobicContact CD-CG2 4.45Å; V139-R143 HydrophobicContact CB-CB 4.17Å; V139-R143 HydrophobicContact CB-CG 4.03Å; V139-R143 HydrophobicContact CG1-CG 4.37Å; V139-R143 HydrophobicContact CG2-CB 4.29Å; V139-R143 HydrophobicContact CG2-CG 4.29Å; V139-H144 HydrophobicContact CG2-CB 4Å
140P98.8Very high98.5Very high38 Ų3830 Ų3025%0.24719%0.187CC..  trans-58.5156170.3-25.136.1000112.4Y142 R143 H144 E427P140-Y142 HydrophobicContact CB-CD1 3.64Å; P140-Y142 HydrophobicContact CB-CE1 3.25Å; P140-Y142 HydrophobicContact CB-CG 4.44Å; P140-Y142 HydrophobicContact CG-CE1 3.87Å; P140-Y142 PolarHBondContact O-N 3.45Å; P140-R143 WeakPolarHBondContact O-CB 3.04Å; P140-R143 PolarHBondContact O-N 3.16Å; P140-R143 VanDerWaalsContact O-N 3.12Å; P140-H144 PolarHBondContact O-N 3.11Å; P140-E427 WeakPolarHBondContact CG-OE1 3.18Å
141L98.9Very high98.3Very high23 Ų2331.7 Ų31.712%0.1220%0.195CC..Hα-helixtrans-61.9-44.9-176.1175.163.7000112K131 A134 R143 H144 I145 F391 D394K131-L141 HydrophobicContact CG-CD1 4.37Å; K131-L141 HydrophobicContact CG-CD2 4Å; A134-L141 HydrophobicContact CB-CB 4.36Å; A134-L141 HydrophobicContact CB-CD1 4.16Å; L141-R143 PolarHBondContact O-N 2.77Å; L141-H144 WeakPolarHBondContact O-CB 3.35Å; L141-H144 PolarHBondContact O-N 3.16Å; L141-H144 VanDerWaalsContact O-N 3.08Å; L141-I145 HydrophobicContact CD1-CD1 3.96Å; L141-I145 HydrophobicContact CD1-CG1 4.08Å; L141-I145 HydrophobicContact CD2-CD1 4.48Å; L141-I145 HydrophobicContact CG-CD1 3.85Å; L141-I145 HydrophobicContact CG-CG1 4.38Å; L141-I145 WeakPolarHBondContact O-CG1 3.25Å; L141-I145 PolarHBondContact O-N 3.22Å; L141-F391 HydrophobicContact CD1-CE2 4.28Å; L141-F391 HydrophobicContact CD2-CD2 3.78Å; L141-F391 HydrophobicContact CD2-CE2 4.08Å; L141-D394 HydrophobicContact CB-CB 4.01Å; L141-D394 WeakPolarHBondContact CB-OD1 3.2Å; L141-D394 HydrophobicContact CD2-CB 3.72Å; L141-D394 HydrophobicContact CG-CB 3.69Å
142Y98.9Very high98.2Very high16 Ų1638.8 Ų38.86%0.06323%0.226CC..Hα-helixtrans-56.1-35.4176.367.9-97.2000112.7P140 A146 V154 D394 V397 G398 I424 E427 L428P140-Y142 HydrophobicContact CB-CD1 3.64Å; P140-Y142 HydrophobicContact CB-CE1 3.25Å; P140-Y142 HydrophobicContact CB-CG 4.44Å; P140-Y142 HydrophobicContact CG-CE1 3.87Å; P140-Y142 PolarHBondContact O-N 3.45Å; Y142-A146 WeakPolarHBondContact O-CB 3.44Å; Y142-A146 PolarHBondContact O-N 2.99Å; Y142-V154 HydrophobicContact CD2-CG1 4.35Å; Y142-V154 HydrophobicContact CD2-CG2 4.47Å; Y142-V154 HydrophobicContact CE2-CG2 4.42Å; Y142-D394 WeakPolarHBondContact CA-O 3.42Å; Y142-D394 WeakPolarHBondContact CB-O 3.5Å; Y142-D394 PolarHBondContact N-OD1 3.31Å; Y142-V397 HydrophobicContact CD2-CG1 4.01Å; Y142-V397 HydrophobicContact CG-CG1 4.14Å; Y142-G398 VanDerWaalsContact O-CA 3.28Å; Y142-G398 WeakPolarHBondContact O-CA 3.35Å; Y142-I424 HydrophobicContact CD1-CB 4.44Å; Y142-I424 HydrophobicContact CD1-CD1 4.16Å; Y142-I424 HydrophobicContact CD1-CG1 3.85Å; Y142-I424 HydrophobicContact CD1-CG2 3.82Å; Y142-I424 HydrophobicContact CE1-CG1 4.21Å; Y142-I424 HydrophobicContact CE1-CG2 3.89Å; Y142-I424 HydrophobicContact CG-CG2 4.17Å; Y142-E427 WeakPolarHBondContact CE1-OE2 3.19Å; Y142-L428 HydrophobicContact CE2-CD2 3.93Å; Y142-L428 HydrophobicContact CE2-CG 4.49Å
143R98.8Very high98Very high53 Ų5341.7 Ų41.720%0.224%0.241CC..Hα-helixtrans-72.4-41.5178-175.860-93.5168.1-9.1111.2V139 P140 L141 I145 A146 D147 H151 K152V139-R143 HydrophobicContact CB-CB 4.17Å; V139-R143 HydrophobicContact CB-CG 4.03Å; V139-R143 HydrophobicContact CG1-CG 4.37Å; V139-R143 HydrophobicContact CG2-CB 4.29Å; V139-R143 HydrophobicContact CG2-CG 4.29Å; P140-R143 WeakPolarHBondContact O-CB 3.04Å; P140-R143 PolarHBondContact O-N 3.16Å; P140-R143 VanDerWaalsContact O-N 3.12Å; L141-R143 PolarHBondContact O-N 2.77Å; R143-I145 VanDerWaalsContact C-N 3.34Å; R143-A146 VanDerWaalsContact CZ-CB 3.41Å; R143-A146 PolarHBondContact O-N 3.09Å; R143-D147 IonicContact CZ-OD1 3.37Å; R143-D147 IonicContact NE-OD1 3.09Å; R143-D147 PolarHBondContact NE-OD1 3.47Å; R143-D147 VanDerWaalsContact NE-OD1 3.09Å; R143-D147 IonicContact NH2-OD1 2.77Å; R143-D147 PolarHBondContact NH2-OD1 3.13Å; R143-D147 VanDerWaalsContact O-CG 3.3Å; R143-D147 PolarHBondContact O-N 2.96Å; R143-H151 PolarHBondContact NH2-O 2.8Å; R143-K152 PolarHBondContact NH1-O 2.9Å
144H98.8Very high98Very high0 Ų042.5 Ų42.50%025%0.246CC..Hα-helixtrans-60.8-43.8173.6-178.768000111.8C130 A134 K137 V139 P140 L141 D147 L148C130-H144 PolarHBondContact O-CD2 3.46Å; C130-H144 VanDerWaalsContact O-CD2 3.28Å; A134-H144 HydrophobicContact CB-CB 3.52Å; K137-H144 WeakPolarHBondContact CD-ND1 3.14Å; K137-H144 WeakPolarHBondContact CE-ND1 3.36Å; K137-H144 PolarHBondContact NZ-ND1 3.03Å; V139-H144 HydrophobicContact CG2-CB 4Å; P140-H144 PolarHBondContact O-N 3.11Å; L141-H144 WeakPolarHBondContact O-CB 3.35Å; L141-H144 PolarHBondContact O-N 3.16Å; L141-H144 VanDerWaalsContact O-N 3.08Å; H144-D147 WeakPolarHBondContact O-CB 3.5Å; H144-D147 PolarHBondContact O-N 3.08Å; H144-L148 WeakPolarHBondContact O-CG 3.27Å; H144-L148 PolarHBondContact O-N 2.96Å; H144-L148 VanDerWaalsContact O-N 3.09Å
145I98.9Very high98Very high0 Ų042.5 Ų42.50%025%0.246CC..Hα-helixtrans-63.2-44.1176-67.6172.2000110.7L141 R143 D147 L148 A149 F391 D394 L395 L399L141-I145 HydrophobicContact CD1-CD1 3.96Å; L141-I145 HydrophobicContact CD1-CG1 4.08Å; L141-I145 HydrophobicContact CD2-CD1 4.48Å; L141-I145 HydrophobicContact CG-CD1 3.85Å; L141-I145 HydrophobicContact CG-CG1 4.38Å; L141-I145 WeakPolarHBondContact O-CG1 3.25Å; L141-I145 PolarHBondContact O-N 3.22Å; R143-I145 VanDerWaalsContact C-N 3.34Å; I145-D147 VanDerWaalsContact C-N 3.28Å; I145-D147 PolarHBondContact O-N 2.87Å; I145-L148 WeakPolarHBondContact O-CB 3.27Å; I145-L148 PolarHBondContact O-N 2.69Å; I145-L148 VanDerWaalsContact O-N 3.12Å; I145-A149 WeakPolarHBondContact O-CB 3.49Å; I145-A149 PolarHBondContact O-N 2.9Å; I145-F391 HydrophobicContact CD1-CE1 4.34Å; I145-F391 HydrophobicContact CD1-CE2 4.23Å; I145-F391 HydrophobicContact CD1-CZ 3.9Å; I145-D394 HydrophobicContact CD1-CB 4.22Å; I145-L395 HydrophobicContact CD1-CB 4.3Å; I145-L395 HydrophobicContact CD1-CD1 4.25Å; I145-L395 HydrophobicContact CG2-CD1 3.93Å; I145-L399 HydrophobicContact CG2-CD2 4.49Å; I145-L399 HydrophobicContact CG2-CG 4.4Å
146A98.7Very high98Very high0 Ų041 Ų410%023%0.233CC..Hα-helixtrans-58.5-39.2175.300000112.3Y142 R143 A149 G150 H151 V154 G398Y142-A146 WeakPolarHBondContact O-CB 3.44Å; Y142-A146 PolarHBondContact O-N 2.99Å; R143-A146 VanDerWaalsContact CZ-CB 3.41Å; R143-A146 PolarHBondContact O-N 3.09Å; A146-A149 CarbonylContact O-C 3.57Å; A146-A149 PolarHBondContact O-N 2.8Å; A146-G150 PolarHBondContact O-N 3.24Å; A146-H151 HydrophobicContact CB-CB 4.32Å; A146-H151 PolarHBondContact O-N 2.96Å; A146-V154 HydrophobicContact CB-CG1 3.83Å; A146-G398 VanDerWaalsContact CA-O 3.28Å; A146-G398 WeakPolarHBondContact CA-O 3.4Å; A146-G398 WeakPolarHBondContact CB-O 3.38Å
147D98.4Very high98.1Very high70 Ų7038.8 Ų38.837%0.37422%0.222SC..Hα-helixtrans-63.2-44.2173.9-62.6-10.1000112.3K137 R143 H144 I145 A149 G150K137-D147 IonicContact NZ-OD2 3.67Å; K137-D147 PolarHBondContact NZ-OD2 2.7Å; R143-D147 IonicContact CZ-OD1 3.37Å; R143-D147 IonicContact NE-OD1 3.09Å; R143-D147 PolarHBondContact NE-OD1 3.47Å; R143-D147 VanDerWaalsContact NE-OD1 3.09Å; R143-D147 IonicContact NH2-OD1 2.77Å; R143-D147 PolarHBondContact NH2-OD1 3.13Å; R143-D147 VanDerWaalsContact O-CG 3.3Å; R143-D147 PolarHBondContact O-N 2.96Å; H144-D147 WeakPolarHBondContact O-CB 3.5Å; H144-D147 PolarHBondContact O-N 3.08Å; I145-D147 VanDerWaalsContact C-N 3.28Å; I145-D147 PolarHBondContact O-N 2.87Å; D147-A149 VanDerWaalsContact C-N 3.27Å; D147-A149 PolarHBondContact O-N 2.85Å; D147-G150 PolarHBondContact O-N 2.9Å; D147-G150 VanDerWaalsContact O-N 3.13Å
148L98.6Very high98.1Very high47 Ų4734.8 Ų34.825%0.24621%0.205CC..Hα-helixtrans-62.8-37177.2-67.2173.4000111.3Q98 H144 I145 G150 I365Q98-L148 HydrophobicContact CB-CD1 3.94Å; Q98-L148 HydrophobicContact CB-CD2 3.89Å; Q98-L148 HydrophobicContact CG-CD1 4.05Å; H144-L148 WeakPolarHBondContact O-CG 3.27Å; H144-L148 PolarHBondContact O-N 2.96Å; H144-L148 VanDerWaalsContact O-N 3.09Å; I145-L148 WeakPolarHBondContact O-CB 3.27Å; I145-L148 PolarHBondContact O-N 2.69Å; I145-L148 VanDerWaalsContact O-N 3.12Å; L148-G150 VanDerWaalsContact C-N 3.32Å; L148-I365 HydrophobicContact CB-CD1 3.81Å; L148-I365 HydrophobicContact CD1-CD1 4.3Å
149A98Very high98.2Very high6 Ų631.6 Ų31.65%0.0517%0.172CC..Hα-helixtrans-77.9-16.5175.900000113.1I145 A146 D147 H151 I365 K369 L399I145-A149 WeakPolarHBondContact O-CB 3.49Å; I145-A149 PolarHBondContact O-N 2.9Å; A146-A149 CarbonylContact O-C 3.57Å; A146-A149 PolarHBondContact O-N 2.8Å; D147-A149 VanDerWaalsContact C-N 3.27Å; D147-A149 PolarHBondContact O-N 2.85Å; A149-H151 VanDerWaalsContact CB-CD2 3.41Å; A149-H151 WeakPolarHBondContact CB-CD2 3.42Å; A149-I365 HydrophobicContact CB-CG2 4.14Å; A149-K369 WeakPolarHBondContact O-CE 3.35Å; A149-K369 PolarHBondContact O-NZ 2.78Å; A149-L399 HydrophobicContact CB-CD2 3.88Å
150G97.2Very high98.2Very high59 Ų5929.4 Ų29.461%0.60816%0.159SC*.THydrogen-bonded Turntrans8119.2-178.500000114.1A146 D147 L148A146-G150 PolarHBondContact O-N 3.24Å; D147-G150 PolarHBondContact O-N 2.9Å; D147-G150 VanDerWaalsContact O-N 3.13Å; L148-G150 VanDerWaalsContact C-N 3.32Å
151H96.3Very high98.2Very high36 Ų3627.6 Ų27.617%0.16715%0.147CC..  trans-87134.5175.2-62.8-60.8000110.7R143 A146 A149 G398 L399R143-H151 PolarHBondContact NH2-O 2.8Å; A146-H151 HydrophobicContact CB-CB 4.32Å; A146-H151 PolarHBondContact O-N 2.96Å; A149-H151 VanDerWaalsContact CB-CD2 3.41Å; A149-H151 WeakPolarHBondContact CB-CD2 3.42Å; H151-G398 PolarHBondContact CD2-O 3.02Å; H151-G398 VanDerWaalsContact CD2-O 3.29Å; H151-L399 PolarHBondContact NE2-O 2.85Å
152K95.1Very high98.2Very high186 Ų18626.6 Ų26.681%0.80914%0.142SC*.SBendtrans-84.4-46.2176.6-68.8-178.2-179.2176.50111.6R143R143-K152 PolarHBondContact NH1-O 2.9Å
153D95.8Very high98.2Very high62 Ų6225.8 Ų25.833%0.33214%0.139SC..SBendtrans-99.8170.5176.5-54-69.2000110.1C400 I444 N445D153-C400 PolarHBondContact O-SG 3.19Å; D153-I444 HydrophobicContact CB-CG2 3.75Å; D153-N445 PolarHBondContact OD2-ND2 2.94Å; D153-N445 PolarHBondContact OD2-OD1 3.03Å
154V97.9Very high98.1Very high16 Ų1623.3 Ų23.310%0.09713%0.129CC..  trans-131.2161.4177.5-64.30000110.7Y142 A146 V397 L428Y142-V154 HydrophobicContact CD2-CG1 4.35Å; Y142-V154 HydrophobicContact CD2-CG2 4.47Å; Y142-V154 HydrophobicContact CE2-CG2 4.42Å; A146-V154 HydrophobicContact CB-CG1 3.83Å; V154-V397 HydrophobicContact CB-CG1 3.75Å; V154-V397 HydrophobicContact CG1-CG1 4.3Å; V154-V397 HydrophobicContact CG2-CG1 4.04Å; V154-L428 HydrophobicContact CG2-CD1 3.83Å; V154-L428 HydrophobicContact CG2-CD2 3.75Å; V154-L428 HydrophobicContact CG2-CG 4.48Å
155I98.6Very high97.9Very high5 Ų523.3 Ų23.33%0.02613%0.129CC..  trans-141.1138.9-179.2-169.4144.5000110.8C400 K433 A435 P442 I444I155-C400 VanDerWaalsContact CG2-CA 3.49Å; I155-C400 HydrophobicContact CG2-CB 3.7Å; I155-K433 HydrophobicContact CD1-CB 4.28Å; I155-K433 HydrophobicContact CG1-CB 4.32Å; I155-A435 HydrophobicContact CD1-CB 4.33Å; I155-A435 HydrophobicContact CG1-CB 4.19Å; I155-P442 HydrophobicContact CD1-CB 3.5Å; I155-P442 VanDerWaalsContact CD1-CB 3.5Å; I155-P442 HydrophobicContact CG1-CB 4.22Å; I155-P442 HydrophobicContact CG2-CB 4.11Å; I155-I444 HydrophobicContact CG2-CG1 4.39Å
156L98.8Very high97.7Very high0 Ų023.3 Ų23.30%013%0.129CC..BIsolated β-bridgetrans-79.2139.9173.4-73.5162.5000110.5F189 V397 L421 I424 E425 A432 K433 F434 A435L156-F189 HydrophobicContact CB-CB 4.32Å; L156-F189 HydrophobicContact CD1-CB 4.01Å; L156-F189 HydrophobicContact CD2-CB 4.5Å; L156-V397 HydrophobicContact CD2-CG2 3.99Å; L156-L421 HydrophobicContact CD2-CD2 4.39Å; L156-I424 HydrophobicContact CD2-CG2 4.37Å; L156-E425 HydrophobicContact CD1-CB 3.45Å; L156-E425 VanDerWaalsContact CD1-CB 3.45Å; L156-E425 HydrophobicContact CD1-CG 3.48Å; L156-E425 VanDerWaalsContact CD1-CG 3.48Å; L156-E425 WeakPolarHBondContact CD1-OE1 2.92Å; L156-E425 HydrophobicContact CD2-CB 4.26Å; L156-E425 HydrophobicContact CG-CB 4.49Å; L156-A432 HydrophobicContact CD1-CB 4.03Å; L156-K433 WeakPolarHBondContact CB-O 3.45Å; L156-K433 PolarHBondContact N-O 2.87Å; L156-F434 HydrophobicContact CB-CD2 4.25Å; L156-A435 WeakPolarHBondContact O-CB 3.37Å; L156-A435 PolarHBondContact O-N 2.62Å
157P98.9Very high97.4Very high0 Ų023.4 Ų23.40%013%0.131CC..PPolyproline II helixtrans-83.9155.7-175.336.4-38.8000112.6P159 F189 V396 G402 I404 L421 F434P157-P159 WeakPolarHBondContact O-CD 3.43Å; P157-F189 HydrophobicContact CG-CE2 4.29Å; P157-F189 VanDerWaalsContact O-CD2 3.25Å; P157-F189 WeakPolarHBondContact O-CD2 3.27Å; P157-V396 HydrophobicContact CB-CG1 4.33Å; P157-V396 HydrophobicContact CB-CG2 3.7Å; P157-V396 HydrophobicContact CG-CG1 3.72Å; P157-V396 HydrophobicContact CG-CG2 4.05Å; P157-G402 CarbonylContact C-O 3.56Å; P157-G402 VanDerWaalsContact CA-C 3.4Å; P157-G402 VanDerWaalsContact CA-O 3.31Å; P157-G402 WeakPolarHBondContact CA-O 3.35Å; P157-I404 HydrophobicContact CB-CB 4.24Å; P157-I404 HydrophobicContact CB-CG2 3.84Å; P157-I404 HydrophobicContact CG-CB 4.23Å; P157-I404 HydrophobicContact CG-CG2 3.53Å; P157-L421 HydrophobicContact CG-CD1 4Å; P157-L421 HydrophobicContact CG-CD2 4.01Å; P157-F434 WeakPolarHBondContact O-CE2 3.42Å
158V98.9Very high97Very high0 Ų022.6 Ų22.60%013%0.131CC..EExtended strand (participates in β ladder)trans-72126.1157.6179.50000108.9L182 V184 G402 Q403 I404 F434 A435 G436 F439V158-L182 HydrophobicContact CG1-CB 3.99Å; V158-V184 HydrophobicContact CG1-CG1 3.96Å; V158-V184 HydrophobicContact CG2-CG1 4.33Å; V158-G402 PolarHBondContact N-O 3.24Å; V158-Q403 WeakPolarHBondContact O-CA 3.48Å; V158-I404 PolarHBondContact O-N 2.86Å; V158-I404 VanDerWaalsContact O-N 3.09Å; V158-F434 HydrophobicContact CB-CZ 4.4Å; V158-F434 HydrophobicContact CG2-CE1 4.3Å; V158-F434 HydrophobicContact CG2-CE2 4.18Å; V158-F434 HydrophobicContact CG2-CZ 3.74Å; V158-A435 HydrophobicContact CG2-CB 4.43Å; V158-G436 VanDerWaalsContact CG2-O 3.27Å; V158-G436 WeakPolarHBondContact CG2-O 3.3Å; V158-F439 HydrophobicContact CB-CB 4.07Å; V158-F439 HydrophobicContact CG2-CB 3.7Å
159P98.9Very high96.3Very high0 Ų020.9 Ų20.90%012%0.121CC..EExtended strand (participates in β ladder)trans-77131.8173.530.7-33.4000111.2P157 F161 P183 F189 A192 I404 Y418P157-P159 WeakPolarHBondContact O-CD 3.43Å; P159-F161 HydrophobicContact CB-CD1 4.44Å; P159-F161 HydrophobicContact CB-CD2 4.38Å; P159-F161 HydrophobicContact CB-CE1 3.81Å; P159-F161 HydrophobicContact CB-CE2 3.77Å; P159-F161 HydrophobicContact CB-CZ 3.44Å; P159-F161 VanDerWaalsContact CB-CZ 3.44Å; P159-F161 HydrophobicContact CG-CD2 4.38Å; P159-F161 HydrophobicContact CG-CE1 4.2Å; P159-F161 HydrophobicContact CG-CE2 3.44Å; P159-F161 VanDerWaalsContact CG-CE2 3.44Å; P159-F161 HydrophobicContact CG-CZ 3.32Å; P159-P183 HydrophobicContact CG-CG 4.08Å; P159-P183 VanDerWaalsContact O-CD 3.27Å; P159-P183 WeakPolarHBondContact O-CD 3.24Å; P159-F189 HydrophobicContact CB-CE2 4.19Å; P159-F189 HydrophobicContact CG-CE2 4.06Å; P159-A192 HydrophobicContact CG-CB 3.97Å; P159-I404 CarbonylContact C-O 3.59Å; P159-I404 WeakPolarHBondContact CA-O 3.11Å; P159-Y418 HydrophobicContact CB-CD1 4.24Å; P159-Y418 HydrophobicContact CB-CE1 3.63Å
160A98.9Very high95.7Very high0 Ų021.2 Ų21.20%012%0.124CC..EExtended strand (participates in β ladder)trans-99.7102.3168.100000109.2M180 L182 M379 I404 K405 Y418A160-M180 HydrophobicContact CB-CB 4.46Å; A160-M180 HydrophobicContact CB-SD 3.81Å; A160-L182 HydrophobicContact CB-CD1 3.98Å; A160-L182 HydrophobicContact CB-CD2 4.04Å; A160-L182 HydrophobicContact CB-CG 3.72Å; A160-M379 HydrophobicContact CB-CE 4.49Å; A160-M379 HydrophobicContact CB-SD 4.45Å; A160-I404 PolarHBondContact N-O 3.21Å; A160-K405 HydrophobicContact CB-CB 3.98Å; A160-Y418 PolarHBondContact O-OH 2.65Å
161F98.9Very high95.2Very high0 Ų022.8 Ų22.80%014%0.14CC..EExtended strand (participates in β ladder)trans-88.7113-175.9-58.2-73.8000110.6P159 V163 M180 I181 P183 M193 G407 P409 Y418P159-F161 HydrophobicContact CB-CD1 4.44Å; P159-F161 HydrophobicContact CB-CD2 4.38Å; P159-F161 HydrophobicContact CB-CE1 3.81Å; P159-F161 HydrophobicContact CB-CE2 3.77Å; P159-F161 HydrophobicContact CB-CZ 3.44Å; P159-F161 VanDerWaalsContact CB-CZ 3.44Å; P159-F161 HydrophobicContact CG-CD2 4.38Å; P159-F161 HydrophobicContact CG-CE1 4.2Å; P159-F161 HydrophobicContact CG-CE2 3.44Å; P159-F161 VanDerWaalsContact CG-CE2 3.44Å; P159-F161 HydrophobicContact CG-CZ 3.32Å; F161-V163 HydrophobicContact CB-CG1 3.95Å; F161-V163 WeakPolarHBondContact O-CG1 3.25Å; F161-V163 PolarHBondContact O-N 3.17Å; F161-V163 VanDerWaalsContact O-N 3.16Å; F161-M180 CarbonylContact O-C 3.58Å; F161-M180 WeakPolarHBondContact O-CA 3.13Å; F161-I181 HydrophobicContact CB-CG1 3.92Å; F161-I181 HydrophobicContact CD2-CG1 4.12Å; F161-I181 PolarHBondContact N-O 3.03Å; F161-I181 PolarHBondContact O-N 3.32Å; F161-P183 HydrophobicContact CE2-CG 4.06Å; F161-M193 HydrophobicContact CE1-CE 3.78Å; F161-M193 HydrophobicContact CE1-SD 3.61Å; F161-M193 HydrophobicContact CZ-CE 3.99Å; F161-M193 HydrophobicContact CZ-SD 3.46Å; F161-M193 WeakPolarHBondContact CZ-SD 3.42Å; F161-G407 WeakPolarHBondContact CA-O 3.11Å; F161-P409 HydrophobicContact CD1-CB 4.44Å; F161-P409 HydrophobicContact CD1-CG 4.44Å; F161-P409 HydrophobicContact CE1-CB 4.49Å; F161-Y418 HydrophobicContact CD1-CE1 4.07Å; F161-Y418 AromaticContact CD1-CE2 3.74Å; F161-Y418 HydrophobicContact CD1-CE2 3.74Å; F161-Y418 AromaticContact CD1-CZ 3.47Å; F161-Y418 VanDerWaalsContact CD1-CZ 3.47Å; F161-Y418 WeakPolarHBondContact CD1-OH 3.34Å; F161-Y418 HydrophobicContact CE1-CD1 4.02Å; F161-Y418 HydrophobicContact CE1-CD2 4.12Å; F161-Y418 AromaticContact CE1-CE1 3.62Å; F161-Y418 HydrophobicContact CE1-CE1 3.62Å; F161-Y418 AromaticContact CE1-CE2 3.73Å; F161-Y418 HydrophobicContact CE1-CE2 3.73Å; F161-Y418 HydrophobicContact CE1-CG 4.26Å; F161-Y418 AromaticContact CE1-CZ 3.46Å; F161-Y418 VanDerWaalsContact CE1-CZ 3.46Å; F161-Y418 HydrophobicContact CZ-CE1 4.45Å
162N98.4Very high94.9Very high2 Ų221.5 Ų21.51%0.01113%0.134CC..EExtended strand (participates in β ladder)trans-68.9106.2170.5-176.712.3000110.1I164 N165 E178 M180 E221 A408N162-I164 PolarHBondContact OD1-O 3.09Å; N162-I164 VanDerWaalsContact OD1-O 3.1Å; N162-N165 PolarHBondContact ND2-ND2 3.36Å; N162-N165 PolarHBondContact ND2-OD1 3.31Å; N162-N165 PolarHBondContact OD1-OD1 2.88Å; N162-E178 HydrophobicContact CB-CB 4.46Å; N162-E178 WeakPolarHBondContact ND2-CG 3.36Å; N162-E178 WeakPolarHBondContact OD1-CB 3.25Å; N162-M180 HydrophobicContact CB-CG 4.16Å; N162-E221 PolarHBondContact ND2-OE2 2.93Å; N162-A408 WeakPolarHBondContact O-CA 3.49Å; N162-A408 WeakPolarHBondContact O-CB 3.17Å; N162-A408 PolarHBondContact O-N 2.79Å
163V98.6Very high94.8Very high0 Ų016.8 Ų16.80%011%0.114CC..EExtended strand (participates in β ladder)trans-113.5-16.2-170.2-69.10000113.9F161 F179 I181 Y200 L203 G223 F224 L238F161-V163 HydrophobicContact CB-CG1 3.95Å; F161-V163 WeakPolarHBondContact O-CG1 3.25Å; F161-V163 PolarHBondContact O-N 3.17Å; F161-V163 VanDerWaalsContact O-N 3.16Å; V163-F179 VanDerWaalsContact CG2-O 3.27Å; V163-F179 WeakPolarHBondContact CG2-O 3.29Å; V163-F179 PolarHBondContact N-O 2.61Å; V163-I181 HydrophobicContact CG1-CD1 4Å; V163-I181 HydrophobicContact CG1-CG1 3.95Å; V163-I181 HydrophobicContact CG2-CG1 4.25Å; V163-I181 HydrophobicContact CG2-CG2 4.03Å; V163-Y200 HydrophobicContact CB-CD2 4.14Å; V163-Y200 HydrophobicContact CG1-CD2 3.79Å; V163-L203 HydrophobicContact CB-CD2 3.8Å; V163-L203 HydrophobicContact CG2-CD2 3.94Å; V163-G223 CarbonylContact O-C 3.57Å; V163-G223 WeakPolarHBondContact O-CA 2.87Å; V163-F224 PolarHBondContact O-N 3.1Å; V163-L238 HydrophobicContact CG2-CD1 4.38Å; V163-L238 HydrophobicContact CG2-CD2 3.45Å; V163-L238 VanDerWaalsContact CG2-CD2 3.45Å
164I98.4Very high94.8Very high0 Ų013.8 Ų13.80%010%0.098CC..EExtended strand (participates in β ladder)trans-131.2126.2166.8-56.3175.3000108.1N162 L174 F179 L203 F224 P226 A234 L237 L238N162-I164 PolarHBondContact OD1-O 3.09Å; N162-I164 VanDerWaalsContact OD1-O 3.1Å; I164-L174 HydrophobicContact CG2-CD2 4.01Å; I164-F179 HydrophobicContact CB-CB 4.15Å; I164-F179 HydrophobicContact CB-CD2 4.39Å; I164-F179 HydrophobicContact CG2-CD2 4.42Å; I164-F179 PolarHBondContact N-O 2.81Å; I164-F179 PolarHBondContact O-N 2.91Å; I164-L203 HydrophobicContact CD1-CD1 4.26Å; I164-L203 HydrophobicContact CD1-CD2 4.32Å; I164-L203 HydrophobicContact CG1-CD2 3.82Å; I164-F224 CarbonylContact C-O 3.5Å; I164-F224 WeakPolarHBondContact CA-O 3.32Å; I164-P226 HydrophobicContact CG2-CG 4.12Å; I164-A234 HydrophobicContact CD1-CB 4.13Å; I164-A234 HydrophobicContact CG2-CB 4.45Å; I164-L237 HydrophobicContact CD1-CB 4.15Å; I164-L237 HydrophobicContact CD1-CD1 4.41Å; I164-L238 HydrophobicContact CD1-CD2 3.71Å; I164-L238 HydrophobicContact CD1-CG 3.97Å; I164-L238 HydrophobicContact CG1-CD2 4.01Å
165N94.1Very high94.7Very high0 Ų013.1 Ų13.10%09%0.094CC..EExtended strand (participates in β ladder)trans-102136.7179.1-68.350.8000110.3N162 H169 A170 N172 G223 F224N162-N165 PolarHBondContact ND2-ND2 3.36Å; N162-N165 PolarHBondContact ND2-OD1 3.31Å; N162-N165 PolarHBondContact OD1-OD1 2.88Å; N165-H169 HydrophobicContact CB-CB 4.41Å; N165-A170 HydrophobicContact CB-CB 3.99Å; N165-A170 WeakPolarHBondContact O-CB 3.37Å; N165-N172 PolarHBondContact O-ND2 3.29Å; N165-G223 WeakPolarHBondContact OD1-CA 3.27Å; N165-G223 PolarHBondContact OD1-N 3.44Å; N165-F224 PolarHBondContact N-O 2.9Å
166G93.8Very high94.6Very high0 Ų012.9 Ų12.90%09%0.093CC..  trans-133.2-146.916800000110.3S168 H169 A170 M176 Q177G166-S168 PolarHBondContact O-N 2.72Å; G166-H169 PolarHBondContact O-N 2.97Å; G166-H169 VanDerWaalsContact O-N 3.09Å; G166-A170 PolarHBondContact O-N 2.91Å; G166-M176 CarbonylContact C-O 3.53Å; G166-M176 WeakPolarHBondContact CA-O 3.41Å; G166-Q177 PolarHBondContact N-O 3.02Å
167G93.1Very high94.5Very high3 Ų313 Ų133%0.0319%0.093CC..G310 helixtrans50-136.8176.900000112.9H169 L174 A175 M176 K273G167-H169 VanDerWaalsContact C-N 3.27Å; G167-H169 PolarHBondContact O-N 3.13Å; G167-L174 PolarHBondContact N-O 3.48Å; G167-A175 WeakPolarHBondContact CA-O 3.28Å; G167-A175 PolarHBondContact N-O 2.83Å; G167-M176 PolarHBondContact N-O 3.06Å; G167-K273 WeakPolarHBondContact O-CD 3.49Å; G167-K273 PolarHBondContact O-NZ 3.46Å
168S89.9Confident94.5Very high53 Ų5313.2 Ų13.237%0.3719%0.094SC..G310 helixtrans-79.5-5.2179-65.30000113.6G166 E261G166-S168 PolarHBondContact O-N 2.72Å; S168-E261 PolarHBondContact OG-OE2 2.65Å
169H84.1Confident94.5Very high10 Ų1013.2 Ų13.25%0.0469%0.094CC..G310 helixtrans-92.8-5.5179.8-67.5173.9000113.9N165 G166 G167 Q177 E178 E221 S384N165-H169 HydrophobicContact CB-CB 4.41Å; G166-H169 PolarHBondContact O-N 2.97Å; G166-H169 VanDerWaalsContact O-N 3.09Å; G167-H169 VanDerWaalsContact C-N 3.27Å; G167-H169 PolarHBondContact O-N 3.13Å; H169-Q177 HydrophobicContact CB-CG 4.33Å; H169-Q177 VanDerWaalsContact CE1-CD 3.45Å; H169-Q177 PolarHBondContact CE1-NE2 3.39Å; H169-Q177 WeakPolarHBondContact ND1-CG 3.23Å; H169-E178 IonicContact CE1-OE1 3.67Å; H169-E178 IonicContact ND1-OE1 3.45Å; H169-E221 IonicContact CE1-OE1 3.63Å; H169-E221 PolarHBondContact CE1-OE1 2.87Å; H169-E221 IonicContact ND1-OE1 3.65Å; H169-S384 WeakPolarHBondContact NE2-CB 3.28Å
170A85.8Confident94.5Very high14 Ų1413.3 Ų13.312%0.11610%0.095CC..SBendtrans-148.7142.2-177.600000113.3N165 G166 N172 A225 K273N165-A170 HydrophobicContact CB-CB 3.99Å; N165-A170 WeakPolarHBondContact O-CB 3.37Å; G166-A170 PolarHBondContact O-N 2.91Å; A170-N172 PolarHBondContact O-N 3.39Å; A170-N172 VanDerWaalsContact O-N 3.08Å; A170-A225 HydrophobicContact CB-CB 3.77Å; A170-K273 PolarHBondContact O-NZ 3.23Å
171G85.8Confident94.5Very high91 Ų9113.3 Ų13.394%0.93810%0.095SC*.SBendtrans-76.418.7176.800000115.7
172N90.5Very high94.5Very high9 Ų913.3 Ų13.35%0.04810%0.095CC..SBendtrans-88.1-172.9174.660.615.3000111.2N165 A170 P226 K273N165-N172 PolarHBondContact O-ND2 3.29Å; A170-N172 PolarHBondContact O-N 3.39Å; A170-N172 VanDerWaalsContact O-N 3.08Å; N172-P226 VanDerWaalsContact CB-O 3.23Å; N172-P226 WeakPolarHBondContact CB-O 3.48Å; N172-P226 PolarHBondContact ND2-O 2.94Å; N172-K273 VanDerWaalsContact O-CD 3.3Å; N172-K273 WeakPolarHBondContact O-CD 3.46Å; N172-K273 WeakPolarHBondContact O-CE 3.21Å; N172-K273 PolarHBondContact O-NZ 3.06Å; N172-K273 PolarHBondContact OD1-NZ 3.08Å
173K93.1Very high94.5Very high87 Ų8713.3 Ų13.338%0.37810%0.095SC..SBendtrans-89.4-23.8176.6-70.5-164.8168.9-1510114.9A175 I228 L229 K273 S274K173-A175 PolarHBondContact O-N 3.41Å; K173-I228 CarbonylContact C-O 3.56Å; K173-L229 HydrophobicContact CB-CB 4.08Å; K173-L229 HydrophobicContact CB-CD1 3.81Å; K173-L229 HydrophobicContact CD-CD1 4.41Å; K173-K273 WeakPolarHBondContact O-CE 3.45Å; K173-S274 PolarHBondContact NZ-OG 3.39Å
174L95.1Very high94.5Very high0 Ų014 Ų140%010%0.099CC..  trans-47.7119-178.4-171.364.3000111.6I164 G167 F179 I228 N231 A234 K273I164-L174 HydrophobicContact CG2-CD2 4.01Å; G167-L174 PolarHBondContact N-O 3.48Å; L174-F179 HydrophobicContact CD1-CE2 4.09Å; L174-F179 HydrophobicContact CD1-CZ 4.11Å; L174-F179 HydrophobicContact CD2-CD2 4.06Å; L174-F179 HydrophobicContact CD2-CE2 3.49Å; L174-F179 VanDerWaalsContact CD2-CE2 3.49Å; L174-F179 HydrophobicContact CD2-CZ 4.29Å; L174-F179 HydrophobicContact CG-CE2 3.93Å; L174-F179 HydrophobicContact CG-CZ 4.44Å; L174-I228 WeakPolarHBondContact CA-O 3.43Å; L174-I228 HydrophobicContact CB-CG1 4.3Å; L174-I228 HydrophobicContact CD1-CD1 4.25Å; L174-I228 HydrophobicContact CD1-CG1 4.19Å; L174-I228 HydrophobicContact CD2-CD1 4.07Å; L174-I228 HydrophobicContact CD2-CG1 4.17Å; L174-I228 HydrophobicContact CG-CG1 4.49Å; L174-I228 PolarHBondContact N-O 2.98Å; L174-N231 HydrophobicContact CD1-CB 4.37Å; L174-N231 VanDerWaalsContact CD1-OD1 3.24Å; L174-N231 WeakPolarHBondContact CD1-OD1 3.5Å; L174-A234 HydrophobicContact CD1-CB 4.47Å; L174-A234 HydrophobicContact CD2-CB 4.31Å; L174-K273 WeakPolarHBondContact O-CE 3.5Å; L174-K273 PolarHBondContact O-NZ 3.38Å
175A95.9Very high94.5Very high1 Ų115 Ų151%0.00811%0.11CC..  trans-77-41.9-174.800000113.5G167 K173 F262 L270 F272G167-A175 WeakPolarHBondContact CA-O 3.28Å; G167-A175 PolarHBondContact N-O 2.83Å; K173-A175 PolarHBondContact O-N 3.41Å; A175-F262 HydrophobicContact CB-CD1 4.35Å; A175-F262 HydrophobicContact CB-CE1 4.45Å; A175-L270 HydrophobicContact CB-CB 4.37Å; A175-L270 HydrophobicContact CB-CD2 4.34Å; A175-L270 WeakPolarHBondContact CB-O 3.37Å; A175-F272 HydrophobicContact CB-CD1 4.02Å; A175-F272 HydrophobicContact CB-CE1 4.11Å
176M97.6Very high94.8Very high0 Ų015.5 Ų15.50%011%0.114CC..SBendtrans-69.5140.2179.3-63.4176.8-172.600110.6G166 G167 F179 N231 M255 V257 L270 L290 Y291 F294G166-M176 CarbonylContact C-O 3.53Å; G166-M176 WeakPolarHBondContact CA-O 3.41Å; G167-M176 PolarHBondContact N-O 3.06Å; M176-F179 HydrophobicContact CB-CE2 3.85Å; M176-F179 HydrophobicContact CB-CZ 3.78Å; M176-F179 HydrophobicContact SD-CZ 4.29Å; M176-N231 WeakPolarHBondContact CB-OD1 3.49Å; M176-N231 HydrophobicContact CE-CB 4.07Å; M176-N231 HydrophobicContact CG-CB 4.43Å; M176-N231 WeakPolarHBondContact CG-OD1 3.18Å; M176-N231 PolarHBondContact N-OD1 2.95Å; M176-N231 HydrophobicContact SD-CB 3.67Å; M176-M255 HydrophobicContact SD-CE 3.28Å; M176-M255 WeakPolarHBondContact SD-CE 3.33Å; M176-V257 HydrophobicContact CG-CG1 4.15Å; M176-V257 HydrophobicContact CG-CG2 4.36Å; M176-V257 HydrophobicContact SD-CG2 4.26Å; M176-L270 HydrophobicContact CE-CD2 4.41Å; M176-L290 HydrophobicContact CE-CD2 4.24Å; M176-Y291 HydrophobicContact CE-CD1 4.31Å; M176-Y291 HydrophobicContact CE-CE1 3.57Å; M176-Y291 HydrophobicContact SD-CE1 4.45Å; M176-F294 HydrophobicContact CE-CE2 3.88Å; M176-F294 HydrophobicContact SD-CE2 4.08Å
177Q96.6Very high95Very high3 Ų319.5 Ų19.51%0.01414%0.142CC..  trans-79.3-43-164.3-171.4163-98.300113.8G166 H169 D256 A258G166-Q177 PolarHBondContact N-O 3.02Å; H169-Q177 HydrophobicContact CB-CG 4.33Å; H169-Q177 VanDerWaalsContact CE1-CD 3.45Å; H169-Q177 PolarHBondContact CE1-NE2 3.39Å; H169-Q177 WeakPolarHBondContact ND1-CG 3.23Å; Q177-D256 PolarHBondContact N-O 2.98Å; Q177-D256 PolarHBondContact NE2-OD2 3.38Å; Q177-A258 HydrophobicContact CB-CB 3.8Å; Q177-A258 HydrophobicContact CG-CB 4.38Å
178E98.3Very high95.2Very high4 Ų422.2 Ų22.22%0.01916%0.156CC..EExtended strand (participates in β ladder)trans-138.9134.4-172.6-43.7178.2169.700111.3N162 H169 M180 M255 D256 K405N162-E178 HydrophobicContact CB-CB 4.46Å; N162-E178 WeakPolarHBondContact ND2-CG 3.36Å; N162-E178 WeakPolarHBondContact OD1-CB 3.25Å; H169-E178 IonicContact CE1-OE1 3.67Å; H169-E178 IonicContact ND1-OE1 3.45Å; E178-M180 HydrophobicContact CB-CE 4.47Å; E178-M180 HydrophobicContact CB-CG 4.36Å; E178-M255 WeakPolarHBondContact O-CA 3.38Å; E178-D256 HydrophobicContact CB-CB 3.81Å; E178-D256 HydrophobicContact CG-CB 3.77Å; E178-D256 PolarHBondContact N-O 2.95Å; E178-D256 PolarHBondContact O-N 3.36Å; E178-K405 IonicContact OE1-NZ 3.48Å; E178-K405 IonicContact OE2-NZ 3.8Å; E178-K405 PolarHBondContact OE2-NZ 2.95Å
179F98.8Very high95.7Very high0 Ų019.7 Ų19.70%014%0.138CC..EExtended strand (participates in β ladder)trans-118.7113.2167.8-61-105.4000108.1V163 I164 L174 M176 N231 A234 L235 L238 M255V163-F179 VanDerWaalsContact CG2-O 3.27Å; V163-F179 WeakPolarHBondContact CG2-O 3.29Å; V163-F179 PolarHBondContact N-O 2.61Å; I164-F179 HydrophobicContact CB-CB 4.15Å; I164-F179 HydrophobicContact CB-CD2 4.39Å; I164-F179 HydrophobicContact CG2-CD2 4.42Å; I164-F179 PolarHBondContact N-O 2.81Å; I164-F179 PolarHBondContact O-N 2.91Å; L174-F179 HydrophobicContact CD1-CE2 4.09Å; L174-F179 HydrophobicContact CD1-CZ 4.11Å; L174-F179 HydrophobicContact CD2-CD2 4.06Å; L174-F179 HydrophobicContact CD2-CE2 3.49Å; L174-F179 VanDerWaalsContact CD2-CE2 3.49Å; L174-F179 HydrophobicContact CD2-CZ 4.29Å; L174-F179 HydrophobicContact CG-CE2 3.93Å; L174-F179 HydrophobicContact CG-CZ 4.44Å; M176-F179 HydrophobicContact CB-CE2 3.85Å; M176-F179 HydrophobicContact CB-CZ 3.78Å; M176-F179 HydrophobicContact SD-CZ 4.29Å; F179-N231 HydrophobicContact CE1-CB 4.44Å; F179-N231 HydrophobicContact CZ-CB 4Å; F179-A234 HydrophobicContact CD1-CB 3.75Å; F179-A234 HydrophobicContact CD2-CB 4Å; F179-A234 HydrophobicContact CE1-CB 3.62Å; F179-A234 HydrophobicContact CE2-CB 3.92Å; F179-A234 HydrophobicContact CG-CB 3.93Å; F179-A234 HydrophobicContact CZ-CB 3.71Å; F179-L235 HydrophobicContact CD1-CD2 3.85Å; F179-L235 HydrophobicContact CD1-CG 4.17Å; F179-L235 HydrophobicContact CE1-CD2 4.19Å; F179-L235 HydrophobicContact CE1-CG 4.07Å; F179-L238 HydrophobicContact CB-CD1 3.79Å; F179-M255 HydrophobicContact CD1-CE 4.25Å; F179-M255 HydrophobicContact CD1-CG 4.35Å; F179-M255 HydrophobicContact CE1-CE 3.67Å; F179-M255 HydrophobicContact CZ-CE 4.25Å
180M98.9Very high96.4Very high2 Ų223.2 Ų23.21%0.0115%0.154CC..EExtended strand (participates in β ladder)trans-108.4147.4-169.4-63.8176.9-90.900112.2A160 F161 N162 E178 L182 I253 G254 D256 K405A160-M180 HydrophobicContact CB-CB 4.46Å; A160-M180 HydrophobicContact CB-SD 3.81Å; F161-M180 CarbonylContact O-C 3.58Å; F161-M180 WeakPolarHBondContact O-CA 3.13Å; N162-M180 HydrophobicContact CB-CG 4.16Å; E178-M180 HydrophobicContact CB-CE 4.47Å; E178-M180 HydrophobicContact CB-CG 4.36Å; M180-L182 HydrophobicContact CB-CD1 4.16Å; M180-I253 VanDerWaalsContact O-CA 3.32Å; M180-I253 WeakPolarHBondContact O-CA 3.41Å; M180-I253 WeakPolarHBondContact O-CG2 3.48Å; M180-G254 WeakPolarHBondContact CA-O 3.41Å; M180-G254 PolarHBondContact N-O 3.17Å; M180-G254 PolarHBondContact O-N 2.93Å; M180-D256 HydrophobicContact CE-CB 4.16Å; M180-K405 HydrophobicContact CE-CD 4.4Å; M180-K405 HydrophobicContact SD-CB 4.13Å; M180-K405 HydrophobicContact SD-CD 4.02Å
181I98.9Very high97Very high0 Ų023.8 Ų23.80%016%0.155CC..EExtended strand (participates in β ladder)trans-109.7136.3166.759173.6000110.1F161 V163 V199 L238 I242 I251F161-I181 HydrophobicContact CB-CG1 3.92Å; F161-I181 HydrophobicContact CD2-CG1 4.12Å; F161-I181 PolarHBondContact N-O 3.03Å; F161-I181 PolarHBondContact O-N 3.32Å; V163-I181 HydrophobicContact CG1-CD1 4Å; V163-I181 HydrophobicContact CG1-CG1 3.95Å; V163-I181 HydrophobicContact CG2-CG1 4.25Å; V163-I181 HydrophobicContact CG2-CG2 4.03Å; I181-V199 HydrophobicContact CD1-CB 3.64Å; I181-V199 HydrophobicContact CD1-CG1 3.51Å; I181-V199 HydrophobicContact CD1-CG2 4.49Å; I181-L238 HydrophobicContact CG2-CD1 4.26Å; I181-L238 HydrophobicContact CG2-CD2 4.39Å; I181-I242 HydrophobicContact CG2-CD1 4.15Å; I181-I242 HydrophobicContact CG2-CG1 4.48Å; I181-I251 HydrophobicContact CB-CG2 3.83Å; I181-I251 HydrophobicContact CG2-CG2 4.12Å
182L98.9Very high97.6Very high1 Ų119.5 Ų19.51%0.00511%0.11CC..EExtended strand (participates in β ladder)trans-124109.5179.1-66.679.9000109.1V158 A160 M180 V184 I251 I252 F439V158-L182 HydrophobicContact CG1-CB 3.99Å; A160-L182 HydrophobicContact CB-CD1 3.98Å; A160-L182 HydrophobicContact CB-CD2 4.04Å; A160-L182 HydrophobicContact CB-CG 3.72Å; M180-L182 HydrophobicContact CB-CD1 4.16Å; L182-V184 HydrophobicContact CB-CG1 4.26Å; L182-V184 PolarHBondContact O-N 3.33Å; L182-I251 WeakPolarHBondContact O-CA 2.89Å; L182-I252 HydrophobicContact CB-CD1 4.21Å; L182-I252 HydrophobicContact CB-CG1 3.67Å; L182-I252 HydrophobicContact CD2-CD1 4.29Å; L182-I252 HydrophobicContact CG-CG1 4.47Å; L182-I252 PolarHBondContact N-O 3.43Å; L182-I252 PolarHBondContact O-N 2.91Å; L182-F439 HydrophobicContact CD2-CE2 4.39Å
183P98.8Very high98Very high1 Ų119.7 Ų19.71%0.00611%0.111CC..  trans-79.462.1-179.535.9-38.5000112P159 F161 G185 A186 A192 I195 K250 I251P159-P183 HydrophobicContact CG-CG 4.08Å; P159-P183 VanDerWaalsContact O-CD 3.27Å; P159-P183 WeakPolarHBondContact O-CD 3.24Å; F161-P183 HydrophobicContact CE2-CG 4.06Å; P183-G185 PolarHBondContact O-N 2.96Å; P183-G185 VanDerWaalsContact O-N 3.16Å; P183-A186 WeakPolarHBondContact O-CB 3.42Å; P183-A186 PolarHBondContact O-N 2.94Å; P183-A186 VanDerWaalsContact O-N 3.11Å; P183-A192 HydrophobicContact CB-CB 4.3Å; P183-A192 HydrophobicContact CG-CB 3.55Å; P183-A192 WeakPolarHBondContact CG-O 3.47Å; P183-I195 HydrophobicContact CB-CB 4.13Å; P183-I195 HydrophobicContact CB-CG2 3.75Å; P183-K250 CarbonylContact C-O 3.26Å; P183-K250 VanDerWaalsContact C-O 3.28Å; P183-K250 WeakPolarHBondContact CA-O 3.38Å; P183-I251 HydrophobicContact CB-CG1 4.31Å
184V98.8Very high98.3Very high14 Ų1421.8 Ų21.89%0.08512%0.117CC..THydrogen-bonded Turntrans-61.9-20.1-178.9-65.80000114.2V158 L182 K250 I252 G436 K437 F439V158-V184 HydrophobicContact CG1-CG1 3.96Å; V158-V184 HydrophobicContact CG2-CG1 4.33Å; L182-V184 HydrophobicContact CB-CG1 4.26Å; L182-V184 PolarHBondContact O-N 3.33Å; V184-K250 PolarHBondContact N-O 3.05Å; V184-K250 VanDerWaalsContact N-O 3.13Å; V184-I252 HydrophobicContact CG1-CD1 3.52Å; V184-I252 HydrophobicContact CG1-CG1 3.87Å; V184-I252 HydrophobicContact CG2-CD1 4.28Å; V184-I252 HydrophobicContact CG2-CG1 4.12Å; V184-I252 HydrophobicContact CG2-CG2 3.82Å; V184-G436 CarbonylContact O-C 3.37Å; V184-G436 VanDerWaalsContact O-C 3.26Å; V184-G436 VanDerWaalsContact O-CA 3.29Å; V184-G436 WeakPolarHBondContact O-CA 3.45Å; V184-K437 PolarHBondContact O-N 3.44Å; V184-F439 HydrophobicContact CG1-CD1 3.87Å; V184-F439 HydrophobicContact CG1-CE1 4.21Å
185G98.6Very high98.5Very high23 Ų2321.8 Ų21.824%0.23712%0.117CC..THydrogen-bonded Turntrans-90.45.917700000114.8P183 K250P183-G185 PolarHBondContact O-N 2.96Å; P183-G185 VanDerWaalsContact O-N 3.16Å; G185-K250 PolarHBondContact N-O 3.08Å
186A98.7Very high98.6Very high9 Ų921.8 Ų21.87%0.07412%0.116CC..  trans-69.8151.5170.300000111.3P183 E191 A192 I195 F434P183-A186 WeakPolarHBondContact O-CB 3.42Å; P183-A186 PolarHBondContact O-N 2.94Å; P183-A186 VanDerWaalsContact O-N 3.11Å; A186-E191 HydrophobicContact CB-CB 4.19Å; A186-E191 HydrophobicContact CB-CG 4.23Å; A186-A192 HydrophobicContact CB-CB 3.76Å; A186-I195 HydrophobicContact CB-CD1 4.13Å; A186-F434 HydrophobicContact CB-CE1 3.94Å; A186-F434 HydrophobicContact CB-CZ 4.25Å; A186-F434 WeakPolarHBondContact O-CD1 3.45Å; A186-F434 VanDerWaalsContact O-CE1 3.29Å; A186-F434 WeakPolarHBondContact O-CE1 3.33Å
187S98.1Very high98.7Very high85 Ų8523 Ų2359%0.59413%0.127SC*.SBendtrans-81.8-26.217859.90000113.2E191S187-E191 VanDerWaalsContact CB-OE2 3.28Å; S187-E191 WeakPolarHBondContact CB-OE2 3.4Å; S187-E191 PolarHBondContact N-OE2 3.36Å; S187-E191 PolarHBondContact OG-OE2 3.33Å
188N98.7Very high98.8Very high60 Ų6026.2 Ų26.232%0.32114%0.142SC..SBendtrans-155.4174.2-178.362.945.4000110.6H190 E191 A192 E425N188-H190 PolarHBondContact OD1-N 3.34Å; N188-E191 PolarHBondContact O-N 2.88Å; N188-E191 WeakPolarHBondContact OD1-CB 3.4Å; N188-E191 PolarHBondContact OD1-N 3.39Å; N188-A192 PolarHBondContact O-N 2.87Å; N188-E425 WeakPolarHBondContact CB-OE1 3.48Å
189F98.9Very high98.8Very high0 Ų026 Ų260%014%0.141CC..Hα-helixtrans-68.5-40.2-176.2-173.5-90.7000112.4L156 P157 P159 E191 A192 M193 Y418 L421 M422 E425 F434L156-F189 HydrophobicContact CB-CB 4.32Å; L156-F189 HydrophobicContact CD1-CB 4.01Å; L156-F189 HydrophobicContact CD2-CB 4.5Å; P157-F189 HydrophobicContact CG-CE2 4.29Å; P157-F189 VanDerWaalsContact O-CD2 3.25Å; P157-F189 WeakPolarHBondContact O-CD2 3.27Å; P159-F189 HydrophobicContact CB-CE2 4.19Å; P159-F189 HydrophobicContact CG-CE2 4.06Å; F189-E191 VanDerWaalsContact C-N 3.32Å; F189-E191 PolarHBondContact O-N 3.46Å; F189-A192 WeakPolarHBondContact O-CB 3.16Å; F189-A192 PolarHBondContact O-N 2.96Å; F189-M193 HydrophobicContact CD1-CG 3.88Å; F189-M193 HydrophobicContact CE1-CG 3.31Å; F189-M193 HydrophobicContact CE1-SD 3.83Å; F189-M193 HydrophobicContact CZ-CG 3.78Å; F189-M193 HydrophobicContact CZ-SD 3.71Å; F189-M193 WeakPolarHBondContact O-CG 3.46Å; F189-M193 PolarHBondContact O-N 3.43Å; F189-Y418 WeakPolarHBondContact CE1-O 3.46Å; F189-Y418 HydrophobicContact CZ-CD1 4.08Å; F189-L421 HydrophobicContact CD1-CB 3.81Å; F189-L421 HydrophobicContact CD2-CB 4.39Å; F189-L421 HydrophobicContact CE1-CB 3.26Å; F189-L421 HydrophobicContact CE1-CD1 4.26Å; F189-L421 HydrophobicContact CE1-CG 4.38Å; F189-L421 HydrophobicContact CE2-CB 3.91Å; F189-L421 HydrophobicContact CE2-CD1 3.63Å; F189-L421 HydrophobicContact CE2-CG 4.32Å; F189-L421 HydrophobicContact CG-CB 4.35Å; F189-L421 HydrophobicContact CZ-CB 3.32Å; F189-L421 HydrophobicContact CZ-CD1 3.41Å; F189-L421 VanDerWaalsContact CZ-CD1 3.41Å; F189-L421 HydrophobicContact CZ-CG 3.98Å; F189-M422 HydrophobicContact CD1-CG 3.8Å; F189-M422 HydrophobicContact CE1-CG 3.83Å; F189-E425 VanDerWaalsContact CB-OE1 3.3Å; F189-E425 WeakPolarHBondContact CB-OE1 3.48Å; F189-E425 PolarHBondContact N-OE1 2.66Å; F189-F434 HydrophobicContact CB-CD2 4.21Å; F189-F434 HydrophobicContact CB-CE2 4.44Å; F189-F434 HydrophobicContact CD2-CE2 4.31Å
190H98.6Very high98.8Very high84 Ų8426.5 Ų26.539%0.38914%0.143SC..Hα-helixtrans-56-44.6173.2-95.167.5000112.6N188 M193 R194 M422 E425N188-H190 PolarHBondContact OD1-N 3.34Å; H190-M193 PolarHBondContact O-N 3.5Å; H190-R194 PolarHBondContact O-N 3.49Å; H190-M422 WeakPolarHBondContact CE1-CB 3.36Å; H190-M422 PolarHBondContact CE1-O 2.89Å; H190-E425 WeakPolarHBondContact CB-OE2 3.3Å; H190-E425 IonicContact CE1-OE2 2.63Å; H190-E425 IonicContact CG-OE2 3.17Å; H190-E425 PolarHBondContact N-OE2 3.07Å; H190-E425 IonicContact ND1-OE2 2.84Å; H190-E425 PolarHBondContact ND1-OE2 3.16Å
191E98.8Very high98.8Very high26 Ų2631.5 Ų31.512%0.12117%0.166CC..Hα-helixtrans-66.6-41.2176.5-172.3-174.1-173.500111A186 S187 N188 F189 M193 R194 I195 K250A186-E191 HydrophobicContact CB-CB 4.19Å; A186-E191 HydrophobicContact CB-CG 4.23Å; S187-E191 VanDerWaalsContact CB-OE2 3.28Å; S187-E191 WeakPolarHBondContact CB-OE2 3.4Å; S187-E191 PolarHBondContact N-OE2 3.36Å; S187-E191 PolarHBondContact OG-OE2 3.33Å; N188-E191 PolarHBondContact O-N 2.88Å; N188-E191 WeakPolarHBondContact OD1-CB 3.4Å; N188-E191 PolarHBondContact OD1-N 3.39Å; F189-E191 VanDerWaalsContact C-N 3.32Å; F189-E191 PolarHBondContact O-N 3.46Å; E191-M193 VanDerWaalsContact C-N 3.31Å; E191-M193 PolarHBondContact O-N 3.37Å; E191-R194 PolarHBondContact O-N 3Å; E191-R194 IonicContact OE1-NH2 3.07Å; E191-I195 HydrophobicContact CG-CD1 3.84Å; E191-I195 HydrophobicContact CG-CG1 4.26Å; E191-I195 WeakPolarHBondContact O-CB 3.27Å; E191-I195 VanDerWaalsContact O-CG1 3.31Å; E191-I195 WeakPolarHBondContact O-CG1 3.42Å; E191-I195 PolarHBondContact O-N 3.07Å; E191-K250 IonicContact OE1-NZ 2.78Å; E191-K250 PolarHBondContact OE1-NZ 2.81Å
192A98.9Very high98.8Very high0 Ų033.7 Ų33.70%018%0.177CC..Hα-helixtrans-57-44.8174.400000111.7P159 P183 A186 N188 F189 I195 G196 F434P159-A192 HydrophobicContact CG-CB 3.97Å; P183-A192 HydrophobicContact CB-CB 4.3Å; P183-A192 HydrophobicContact CG-CB 3.55Å; P183-A192 WeakPolarHBondContact CG-O 3.47Å; A186-A192 HydrophobicContact CB-CB 3.76Å; N188-A192 PolarHBondContact O-N 2.87Å; F189-A192 WeakPolarHBondContact O-CB 3.16Å; F189-A192 PolarHBondContact O-N 2.96Å; A192-I195 PolarHBondContact O-N 3.41Å; A192-G196 PolarHBondContact O-N 2.96Å; A192-F434 HydrophobicContact CB-CE2 4.09Å; A192-F434 HydrophobicContact CB-CZ 3.79Å
193M98.9Very high98.8Very high14 Ų1433.6 Ų33.67%0.06918%0.177CC..Hα-helixtrans-61-45.9175-75.5-55.3-49.200112.6F161 F189 H190 E191 G196 A197 Y418 M422F161-M193 HydrophobicContact CE1-CE 3.78Å; F161-M193 HydrophobicContact CE1-SD 3.61Å; F161-M193 HydrophobicContact CZ-CE 3.99Å; F161-M193 HydrophobicContact CZ-SD 3.46Å; F161-M193 WeakPolarHBondContact CZ-SD 3.42Å; F189-M193 HydrophobicContact CD1-CG 3.88Å; F189-M193 HydrophobicContact CE1-CG 3.31Å; F189-M193 HydrophobicContact CE1-SD 3.83Å; F189-M193 HydrophobicContact CZ-CG 3.78Å; F189-M193 HydrophobicContact CZ-SD 3.71Å; F189-M193 WeakPolarHBondContact O-CG 3.46Å; F189-M193 PolarHBondContact O-N 3.43Å; H190-M193 PolarHBondContact O-N 3.5Å; E191-M193 VanDerWaalsContact C-N 3.31Å; E191-M193 PolarHBondContact O-N 3.37Å; M193-G196 PolarHBondContact O-N 3.45Å; M193-A197 WeakPolarHBondContact O-CB 3.2Å; M193-A197 PolarHBondContact O-N 3.46Å; M193-Y418 HydrophobicContact CE-CD1 4.3Å; M193-Y418 HydrophobicContact CE-CD2 4.1Å; M193-Y418 HydrophobicContact CE-CG 3.73Å; M193-Y418 VanDerWaalsContact SD-CB 3.57Å; M193-Y418 HydrophobicContact SD-CD1 3.59Å; M193-Y418 VanDerWaalsContact SD-CD1 3.59Å; M193-Y418 HydrophobicContact SD-CD2 4.45Å; M193-Y418 HydrophobicContact SD-CE1 4.38Å; M193-Y418 HydrophobicContact SD-CG 3.62Å; M193-M422 HydrophobicContact CB-SD 4.17Å; M193-M422 HydrophobicContact CG-CG 4.13Å; M193-M422 HydrophobicContact CG-SD 4.1Å
194R98.9Very high98.8Very high131 Ų13137.7 Ų37.749%0.49420%0.195SC..Hα-helixtrans-60.2-50.5177.1-178.1-174.767.7177.8-1111.4H190 E191 G196 A197 E198H190-R194 PolarHBondContact O-N 3.49Å; E191-R194 PolarHBondContact O-N 3Å; E191-R194 IonicContact OE1-NH2 3.07Å; R194-G196 VanDerWaalsContact C-N 3.34Å; R194-G196 PolarHBondContact O-N 3.02Å; R194-A197 PolarHBondContact O-N 2.95Å; R194-E198 WeakPolarHBondContact CD-OE1 3.32Å; R194-E198 HydrophobicContact CG-CG 4.4Å; R194-E198 VanDerWaalsContact CG-OE1 3.23Å; R194-E198 WeakPolarHBondContact CG-OE1 3.08Å; R194-E198 WeakPolarHBondContact O-CG 3.32Å; R194-E198 PolarHBondContact O-N 3.14Å
195I98.9Very high98.8Very high0 Ų041.7 Ų41.70%022%0.215CC..Hα-helixtrans-57.4-48.4179.6-71.8172.8000110.3P183 A186 E191 A192 A197 E198 V199 Y247 K250 I251P183-I195 HydrophobicContact CB-CB 4.13Å; P183-I195 HydrophobicContact CB-CG2 3.75Å; A186-I195 HydrophobicContact CB-CD1 4.13Å; E191-I195 HydrophobicContact CG-CD1 3.84Å; E191-I195 HydrophobicContact CG-CG1 4.26Å; E191-I195 WeakPolarHBondContact O-CB 3.27Å; E191-I195 VanDerWaalsContact O-CG1 3.31Å; E191-I195 WeakPolarHBondContact O-CG1 3.42Å; E191-I195 PolarHBondContact O-N 3.07Å; A192-I195 PolarHBondContact O-N 3.41Å; I195-A197 PolarHBondContact O-N 2.53Å; I195-E198 PolarHBondContact O-N 3.13Å; I195-V199 WeakPolarHBondContact O-CG2 3.4Å; I195-V199 PolarHBondContact O-N 3.43Å; I195-Y247 HydrophobicContact CB-CD2 4.46Å; I195-Y247 HydrophobicContact CB-CE2 4.41Å; I195-Y247 HydrophobicContact CD1-CD1 4.27Å; I195-Y247 HydrophobicContact CD1-CE1 4.25Å; I195-Y247 HydrophobicContact CG1-CD1 4.1Å; I195-Y247 HydrophobicContact CG1-CD2 4.41Å; I195-Y247 HydrophobicContact CG1-CE1 3.82Å; I195-Y247 HydrophobicContact CG1-CE2 4.16Å; I195-Y247 HydrophobicContact CG1-CG 4.39Å; I195-Y247 HydrophobicContact CG2-CD1 4.39Å; I195-Y247 HydrophobicContact CG2-CD2 3.83Å; I195-Y247 HydrophobicContact CG2-CE2 4.26Å; I195-Y247 HydrophobicContact CG2-CG 3.9Å; I195-K250 HydrophobicContact CD1-CD 3.66Å; I195-I251 HydrophobicContact CG2-CD1 3.61Å; I195-I251 HydrophobicContact CG2-CG1 3.9Å
196G98.9Very high98.8Very high0 Ų041.1 Ų41.10%021%0.208CC..Hα-helixtrans-59.1-45.4178.200000113A192 M193 R194 V199 Y200A192-G196 PolarHBondContact O-N 2.96Å; M193-G196 PolarHBondContact O-N 3.45Å; R194-G196 VanDerWaalsContact C-N 3.34Å; R194-G196 PolarHBondContact O-N 3.02Å; G196-V199 PolarHBondContact O-N 2.93Å; G196-Y200 WeakPolarHBondContact O-CB 3.29Å; G196-Y200 PolarHBondContact O-N 3.27Å
197A98.9Very high98.8Very high27 Ų2740.7 Ų40.722%0.22320%0.204CC..Hα-helixtrans-65.9-40.9178.500000112.9M193 R194 I195 Y200 H201 P409M193-A197 WeakPolarHBondContact O-CB 3.2Å; M193-A197 PolarHBondContact O-N 3.46Å; R194-A197 PolarHBondContact O-N 2.95Å; I195-A197 PolarHBondContact O-N 2.53Å; A197-Y200 PolarHBondContact O-N 2.99Å; A197-H201 PolarHBondContact O-N 3.37Å; A197-H201 PolarHBondContact O-ND1 3.19Å; A197-P409 HydrophobicContact CB-CB 4.27Å; A197-P409 HydrophobicContact CB-CG 4.49Å
198E98.9Very high98.8Very high70 Ų7042.1 Ų42.133%0.32720%0.2SC..Hα-helixtrans-65.9-40.9177.5-74.4176.5-168.100112.2R194 I195 H201 N202 Y247R194-E198 WeakPolarHBondContact CD-OE1 3.32Å; R194-E198 HydrophobicContact CG-CG 4.4Å; R194-E198 VanDerWaalsContact CG-OE1 3.23Å; R194-E198 WeakPolarHBondContact CG-OE1 3.08Å; R194-E198 WeakPolarHBondContact O-CG 3.32Å; R194-E198 PolarHBondContact O-N 3.14Å; I195-E198 PolarHBondContact O-N 3.13Å; E198-H201 PolarHBondContact O-N 3.46Å; E198-N202 PolarHBondContact O-N 3.46Å; E198-N202 PolarHBondContact O-ND2 3.4Å; E198-Y247 HydrophobicContact CB-CE2 4.15Å; E198-Y247 WeakPolarHBondContact OE2-CE2 3.37Å; E198-Y247 VanDerWaalsContact OE2-CZ 3.26Å; E198-Y247 PolarHBondContact OE2-OH 3.07Å
199V98.9Very high98.7Very high0 Ų043.5 Ų43.50%022%0.219CC..Hα-helixtrans-65.5-43.3172.9174.40000111.2I181 I195 G196 H201 N202 L203 A241 I242 A245 Y247 I251I181-V199 HydrophobicContact CD1-CB 3.64Å; I181-V199 HydrophobicContact CD1-CG1 3.51Å; I181-V199 HydrophobicContact CD1-CG2 4.49Å; I195-V199 WeakPolarHBondContact O-CG2 3.4Å; I195-V199 PolarHBondContact O-N 3.43Å; G196-V199 PolarHBondContact O-N 2.93Å; V199-H201 VanDerWaalsContact C-N 3.33Å; V199-H201 PolarHBondContact O-N 3.35Å; V199-N202 PolarHBondContact O-N 3.37Å; V199-L203 VanDerWaalsContact O-CB 3.31Å; V199-L203 WeakPolarHBondContact O-CB 3.33Å; V199-L203 PolarHBondContact O-N 2.71Å; V199-A241 HydrophobicContact CG1-CB 4.22Å; V199-I242 HydrophobicContact CG1-CG1 3.89Å; V199-I242 HydrophobicContact CG2-CG1 4.47Å; V199-A245 HydrophobicContact CB-CB 4.44Å; V199-A245 HydrophobicContact CG2-CB 3.58Å; V199-Y247 HydrophobicContact CG2-CD2 4.03Å; V199-I251 HydrophobicContact CB-CD1 4.42Å; V199-I251 HydrophobicContact CG2-CD1 3.47Å; V199-I251 VanDerWaalsContact CG2-CD1 3.47Å
200Y98.9Very high98.7Very high10 Ų1049.1 Ų49.14%0.03924%0.244CC..Hα-helixtrans-58.4-42.8177177.5-100.1000112.3V163 G196 A197 L203 K204 V218 G222 F224 A408 P409 C410V163-Y200 HydrophobicContact CB-CD2 4.14Å; V163-Y200 HydrophobicContact CG1-CD2 3.79Å; G196-Y200 WeakPolarHBondContact O-CB 3.29Å; G196-Y200 PolarHBondContact O-N 3.27Å; A197-Y200 PolarHBondContact O-N 2.99Å; Y200-L203 WeakPolarHBondContact O-CB 3.47Å; Y200-L203 PolarHBondContact O-N 2.68Å; Y200-K204 PolarHBondContact O-N 3.17Å; Y200-V218 VanDerWaalsContact OH-CG1 3.31Å; Y200-V218 WeakPolarHBondContact OH-CG1 3.46Å; Y200-G222 WeakPolarHBondContact CE2-O 3.36Å; Y200-G222 PolarHBondContact OH-O 2.77Å; Y200-F224 HydrophobicContact CD1-CZ 4.3Å; Y200-F224 HydrophobicContact CD2-CD2 4.42Å; Y200-F224 AromaticContact CD2-CE2 3.66Å; Y200-F224 HydrophobicContact CD2-CE2 3.66Å; Y200-F224 HydrophobicContact CD2-CZ 4.1Å; Y200-F224 HydrophobicContact CE1-CE2 4.27Å; Y200-F224 AromaticContact CE1-CZ 3.71Å; Y200-F224 HydrophobicContact CE1-CZ 3.71Å; Y200-F224 AromaticContact CE2-CD2 4Å; Y200-F224 HydrophobicContact CE2-CD2 4Å; Y200-F224 HydrophobicContact CE2-CE1 4.28Å; Y200-F224 AromaticContact CE2-CE2 3.38Å; Y200-F224 HydrophobicContact CE2-CE2 3.38Å; Y200-F224 AromaticContact CE2-CZ 3.52Å; Y200-F224 HydrophobicContact CE2-CZ 3.52Å; Y200-F224 HydrophobicContact CG-CE2 4.25Å; Y200-F224 HydrophobicContact CG-CZ 4.47Å; Y200-F224 AromaticContact CZ-CE1 3.89Å; Y200-F224 AromaticContact CZ-CE2 3.71Å; Y200-F224 AromaticContact CZ-CZ 3.29Å; Y200-F224 WeakPolarHBondContact O-CE2 3.31Å; Y200-F224 WeakPolarHBondContact OH-CZ 3.31Å; Y200-A408 HydrophobicContact CD2-CB 4.45Å; Y200-A408 HydrophobicContact CE2-CB 4.01Å; Y200-P409 HydrophobicContact CD1-CG 4.12Å; Y200-P409 HydrophobicContact CD2-CG 4.33Å; Y200-P409 HydrophobicContact CG-CG 3.78Å; Y200-C410 HydrophobicContact CE1-CB 3.94Å; Y200-C410 WeakPolarHBondContact OH-CB 3.2Å; Y200-C410 PolarHBondContact OH-SG 3.18Å
201H98.9Very high98.6Very high107 Ų10748.2 Ų48.250%0.49524%0.237SC..Hα-helixtrans-69.7-35.9175.9-66.5142000113.2A197 E198 V199 K204 N205A197-H201 PolarHBondContact O-N 3.37Å; A197-H201 PolarHBondContact O-ND1 3.19Å; E198-H201 PolarHBondContact O-N 3.46Å; V199-H201 VanDerWaalsContact C-N 3.33Å; V199-H201 PolarHBondContact O-N 3.35Å; H201-K204 WeakPolarHBondContact O-CB 3.23Å; H201-K204 PolarHBondContact O-N 3.32Å; H201-N205 PolarHBondContact O-N 3.17Å; H201-N205 PolarHBondContact O-ND2 2.97Å
202N98.8Very high98.5Very high45 Ų4548.5 Ų48.524%0.24125%0.247CC..Hα-helixtrans-64.8-42.6172-86.7-77.3000111.5E198 V199 K204 N205 V206 A245E198-N202 PolarHBondContact O-N 3.46Å; E198-N202 PolarHBondContact O-ND2 3.4Å; V199-N202 PolarHBondContact O-N 3.37Å; N202-K204 VanDerWaalsContact C-N 3.31Å; N202-K204 PolarHBondContact O-N 3.04Å; N202-N205 WeakPolarHBondContact O-CB 3.45Å; N202-N205 PolarHBondContact O-N 2.64Å; N202-N205 VanDerWaalsContact O-N 3.07Å; N202-V206 WeakPolarHBondContact O-CG2 3.41Å; N202-V206 PolarHBondContact O-N 3.17Å; N202-A245 HydrophobicContact CB-CB 4.43Å
203L98.8Very high98.3Very high0 Ų055.2 Ų55.20%028%0.276CS..Hα-helixtrans-58.8-43.6175.3179.862.8000111.2V163 I164 V199 Y200 N205 V206 I207 F224 L237 L238 A241V163-L203 HydrophobicContact CB-CD2 3.8Å; V163-L203 HydrophobicContact CG2-CD2 3.94Å; I164-L203 HydrophobicContact CD1-CD1 4.26Å; I164-L203 HydrophobicContact CD1-CD2 4.32Å; I164-L203 HydrophobicContact CG1-CD2 3.82Å; V199-L203 VanDerWaalsContact O-CB 3.31Å; V199-L203 WeakPolarHBondContact O-CB 3.33Å; V199-L203 PolarHBondContact O-N 2.71Å; Y200-L203 WeakPolarHBondContact O-CB 3.47Å; Y200-L203 PolarHBondContact O-N 2.68Å; L203-N205 VanDerWaalsContact C-N 3.26Å; L203-N205 PolarHBondContact O-N 3.39Å; L203-V206 PolarHBondContact O-N 2.99Å; L203-I207 HydrophobicContact CD1-CD1 3.88Å; L203-I207 HydrophobicContact CD1-CG1 4.09Å; L203-I207 HydrophobicContact CD2-CD1 4.45Å; L203-I207 HydrophobicContact CG-CD1 3.8Å; L203-I207 HydrophobicContact CG-CG1 4.38Å; L203-I207 WeakPolarHBondContact O-CB 3.41Å; L203-I207 WeakPolarHBondContact O-CG1 3.27Å; L203-I207 PolarHBondContact O-N 2.88Å; L203-F224 HydrophobicContact CB-CE2 4.33Å; L203-F224 HydrophobicContact CD2-CD2 3.87Å; L203-F224 HydrophobicContact CD2-CE2 4.23Å; L203-F224 HydrophobicContact CG-CD2 3.94Å; L203-F224 HydrophobicContact CG-CE2 4.18Å; L203-L237 HydrophobicContact CD1-CB 3.98Å; L203-L238 HydrophobicContact CD1-CD2 4.11Å; L203-L238 HydrophobicContact CD2-CD2 3.65Å; L203-L238 HydrophobicContact CG-CD2 4.5Å; L203-A241 HydrophobicContact CB-CB 3.67Å; L203-A241 HydrophobicContact CD1-CB 3.94Å; L203-A241 HydrophobicContact CG-CB 4.4Å
204K98.8Very high98.2Very high86 Ų8660 Ų6037%0.37430%0.302SS..Hα-helixtrans-52-46.4172.7-166.9173.7179.6170.20111.9Y200 H201 N202 K208 T216 F224Y200-K204 PolarHBondContact O-N 3.17Å; H201-K204 WeakPolarHBondContact O-CB 3.23Å; H201-K204 PolarHBondContact O-N 3.32Å; N202-K204 VanDerWaalsContact C-N 3.31Å; N202-K204 PolarHBondContact O-N 3.04Å; K204-K208 VanDerWaalsContact O-CB 3.22Å; K204-K208 WeakPolarHBondContact O-CB 3.41Å; K204-K208 PolarHBondContact O-N 2.95Å; K204-T216 HydrophobicContact CG-CG2 3.86Å; K204-T216 WeakPolarHBondContact O-CG2 3.38Å; K204-F224 HydrophobicContact CB-CE1 4.03Å; K204-F224 HydrophobicContact CB-CE2 3.85Å; K204-F224 HydrophobicContact CB-CZ 3.36Å; K204-F224 HydrophobicContact CD-CE1 4.08Å; K204-F224 HydrophobicContact CD-CZ 3.99Å; K204-F224 HydrophobicContact CG-CE1 3.74Å; K204-F224 HydrophobicContact CG-CE2 4.47Å; K204-F224 HydrophobicContact CG-CZ 3.6Å
205N98.6Very high98Very high98 Ų9854.5 Ų54.552%0.52428%0.284SS..Hα-helixtrans-70-39.6-179-68.3-28.9000112.1H201 N202 L203 K208 A209H201-N205 PolarHBondContact O-N 3.17Å; H201-N205 PolarHBondContact O-ND2 2.97Å; N202-N205 WeakPolarHBondContact O-CB 3.45Å; N202-N205 PolarHBondContact O-N 2.64Å; N202-N205 VanDerWaalsContact O-N 3.07Å; L203-N205 VanDerWaalsContact C-N 3.26Å; L203-N205 PolarHBondContact O-N 3.39Å; N205-K208 PolarHBondContact O-N 2.71Å; N205-A209 WeakPolarHBondContact O-CB 3.47Å; N205-A209 PolarHBondContact O-N 3.03Å
206V98.5Very high97.9Very high12 Ų1255.4 Ų55.47%0.07329%0.29CS..Hα-helixtrans-61-49.4174.71730000110.5N202 L203 A209 K210 L237 T240 K244N202-V206 WeakPolarHBondContact O-CG2 3.41Å; N202-V206 PolarHBondContact O-N 3.17Å; L203-V206 PolarHBondContact O-N 2.99Å; V206-A209 PolarHBondContact O-N 2.79Å; V206-K210 PolarHBondContact O-N 3.41Å; V206-K210 VanDerWaalsContact O-N 3.09Å; V206-L237 HydrophobicContact CG1-CD2 3.7Å; V206-T240 HydrophobicContact CG1-CG2 4.18Å; V206-T240 HydrophobicContact CG2-CG2 4.03Å; V206-K244 HydrophobicContact CG2-CD 3.76Å
207I98.4Very high97.8Very high0 Ų060.7 Ų60.70%032%0.319CS..Hα-helixtrans-62.2-46.9177.9-69.9173.1000110.6L203 A209 K210 Y211 A215 T216 F224 P226 L237L203-I207 HydrophobicContact CD1-CD1 3.88Å; L203-I207 HydrophobicContact CD1-CG1 4.09Å; L203-I207 HydrophobicContact CD2-CD1 4.45Å; L203-I207 HydrophobicContact CG-CD1 3.8Å; L203-I207 HydrophobicContact CG-CG1 4.38Å; L203-I207 WeakPolarHBondContact O-CB 3.41Å; L203-I207 WeakPolarHBondContact O-CG1 3.27Å; L203-I207 PolarHBondContact O-N 2.88Å; I207-A209 VanDerWaalsContact C-N 3.28Å; I207-A209 PolarHBondContact O-N 3.32Å; I207-K210 PolarHBondContact O-N 3.49Å; I207-Y211 HydrophobicContact CG2-CD2 4.16Å; I207-Y211 PolarHBondContact O-N 2.75Å; I207-A215 HydrophobicContact CG2-CB 3.7Å; I207-A215 WeakPolarHBondContact CG2-O 3.49Å; I207-T216 HydrophobicContact CB-CG2 4.48Å; I207-T216 HydrophobicContact CG2-CG2 4.12Å; I207-F224 HydrophobicContact CD1-CB 3.52Å; I207-F224 HydrophobicContact CD1-CD2 3.68Å; I207-F224 HydrophobicContact CD1-CG 3.78Å; I207-P226 HydrophobicContact CD1-CG 4.26Å; I207-P226 HydrophobicContact CG2-CB 4.13Å; I207-L237 HydrophobicContact CG1-CD1 4.34Å
208K98.3Very high97.7Very high115 Ų11562 Ų6250%0.532%0.323SS..Hα-helixtrans-57.2-42.7178.2-173.6175.7-179.1-174.20112.2K204 N205 G212 K213 T216K204-K208 VanDerWaalsContact O-CB 3.22Å; K204-K208 WeakPolarHBondContact O-CB 3.41Å; K204-K208 PolarHBondContact O-N 2.95Å; N205-K208 PolarHBondContact O-N 2.71Å; K208-G212 CarbonylContact O-C 3.51Å; K208-G212 WeakPolarHBondContact O-CA 3.27Å; K208-G212 PolarHBondContact O-N 2.97Å; K208-K213 HydrophobicContact CG-CB 4.45Å; K208-T216 HydrophobicContact CB-CG2 3.73Å; K208-T216 HydrophobicContact CG-CG2 4.44Å
209A98Very high97.3Very high89 Ų8959 Ų5974%0.73631%0.312SS*.Hα-helixtrans-68.4-36.8-179.700000112.2N205 V206 I207N205-A209 WeakPolarHBondContact O-CB 3.47Å; N205-A209 PolarHBondContact O-N 3.03Å; V206-A209 PolarHBondContact O-N 2.79Å; I207-A209 VanDerWaalsContact C-N 3.28Å; I207-A209 PolarHBondContact O-N 3.32Å
210K97.7Very high96.9Very high118 Ų11861.4 Ų61.451%0.51333%0.325SS..Hα-helixtrans-88.1-39.8-175-169.6173.2173.5-1630114V206 I207 E233 L237V206-K210 PolarHBondContact O-N 3.41Å; V206-K210 VanDerWaalsContact O-N 3.09Å; I207-K210 PolarHBondContact O-N 3.49Å; K210-E233 WeakPolarHBondContact CE-OE1 3.46Å; K210-E233 IonicContact NZ-OE1 2.7Å; K210-E233 PolarHBondContact NZ-OE1 3.45Å; K210-L237 HydrophobicContact CD-CD2 4.2Å
211Y96.5Very high96.8Very high64 Ų6461.1 Ų61.125%0.25132%0.324SS..Hα-helixtrans-1203.1-173-50.4-79.6000113.9I207 P226 I228 E233 L237I207-Y211 HydrophobicContact CG2-CD2 4.16Å; I207-Y211 PolarHBondContact O-N 2.75Å; Y211-P226 HydrophobicContact CD2-CB 4.15Å; Y211-P226 HydrophobicContact CE2-CB 4.39Å; Y211-I228 HydrophobicContact CE1-CG2 3.7Å; Y211-I228 HydrophobicContact CE2-CG2 4.22Å; Y211-I228 WeakPolarHBondContact OH-CG2 3.43Å; Y211-E233 VanDerWaalsContact OH-CG 3.31Å; Y211-E233 WeakPolarHBondContact OH-CG 3.3Å; Y211-E233 PolarHBondContact OH-OE1 2.94Å; Y211-L237 HydrophobicContact CE2-CD1 3.79Å; Y211-L237 HydrophobicContact CE2-CD2 3.9Å; Y211-L237 HydrophobicContact CE2-CG 4.45Å
212G97Very high96.7Very high32 Ų3256 Ų5633%0.3330%0.3SS..  trans86170.7-179.300000113.9K208 D214 A215K208-G212 CarbonylContact O-C 3.51Å; K208-G212 WeakPolarHBondContact O-CA 3.27Å; K208-G212 PolarHBondContact O-N 2.97Å; G212-D214 VanDerWaalsContact C-N 3.3Å; G212-D214 PolarHBondContact O-N 2.8Å; G212-A215 PolarHBondContact O-N 2.82Å
213K95.8Very high96.7Very high142 Ų14253.9 Ų53.962%0.61729%0.289SS*.G310 helixtrans-63-33-173.669.9-178.7-177.2173.90113.5K208 A215 T216K208-K213 HydrophobicContact CG-CB 4.45Å; K213-A215 PolarHBondContact O-N 2.86Å; K213-T216 WeakPolarHBondContact O-CB 3.49Å; K213-T216 PolarHBondContact O-N 3.02Å; K213-T216 PolarHBondContact O-OG1 2.91Å
214D95Very high96.7Very high115 Ų11553.9 Ų53.962%0.61529%0.289SS*.G310 helixtrans-71.2-25.1-174.1-58.2-26.6000111.4G212 T216 N217G212-D214 VanDerWaalsContact C-N 3.3Å; G212-D214 PolarHBondContact O-N 2.8Å; D214-T216 PolarHBondContact O-N 3.44Å; D214-N217 PolarHBondContact O-N 3.49Å; D214-N217 PolarHBondContact O-ND2 2.85Å; D214-N217 VanDerWaalsContact O-ND2 3.1Å
215A95.8Very high96.5Very high14 Ų1451.1 Ų51.112%0.11628%0.282CS..G310 helixtrans-70.3-6.5172.100000113.7I207 G212 K213 P226I207-A215 HydrophobicContact CG2-CB 3.7Å; I207-A215 WeakPolarHBondContact CG2-O 3.49Å; G212-A215 PolarHBondContact O-N 2.82Å; K213-A215 PolarHBondContact O-N 2.86Å; A215-P226 HydrophobicContact CB-CB 4.42Å
216T96.9Very high96.4Very high20 Ų2046.4 Ų46.412%0.12326%0.257CS..G310 helixtrans-94.87.5175.669.30000114K204 I207 K208 K213 D214 F224K204-T216 HydrophobicContact CG-CG2 3.86Å; K204-T216 WeakPolarHBondContact O-CG2 3.38Å; I207-T216 HydrophobicContact CB-CG2 4.48Å; I207-T216 HydrophobicContact CG2-CG2 4.12Å; K208-T216 HydrophobicContact CB-CG2 3.73Å; K208-T216 HydrophobicContact CG-CG2 4.44Å; K213-T216 WeakPolarHBondContact O-CB 3.49Å; K213-T216 PolarHBondContact O-N 3.02Å; K213-T216 PolarHBondContact O-OG1 2.91Å; D214-T216 PolarHBondContact O-N 3.44Å; T216-F224 WeakPolarHBondContact O-CD1 3.49Å; T216-F224 WeakPolarHBondContact O-CE1 3.36Å
217N96.5Very high96Very high111 Ų11151.6 Ų51.659%0.59428%0.284SS*.  trans-64.6155.1162.7-67.7-32.2000109.9D214 A225D214-N217 PolarHBondContact O-N 3.49Å; D214-N217 PolarHBondContact O-ND2 2.85Å; D214-N217 VanDerWaalsContact O-ND2 3.1Å; N217-A225 PolarHBondContact O-N 2.96Å
218V96.1Very high95.8Very high53 Ų5351.7 Ų51.732%0.32129%0.285SS..BIsolated β-bridgetrans-109.9146.2-173.8-60.30000111.2Y200 G222 G223 F224 R411Y200-V218 VanDerWaalsContact OH-CG1 3.31Å; Y200-V218 WeakPolarHBondContact OH-CG1 3.46Å; V218-G222 WeakPolarHBondContact CG1-O 3.23Å; V218-G223 CarbonylContact C-O 3.55Å; V218-G223 WeakPolarHBondContact CA-O 3.35Å; V218-F224 HydrophobicContact CG1-CD1 4.15Å; V218-F224 HydrophobicContact CG1-CE1 4.18Å; V218-R411 HydrophobicContact CG2-CG 4.47Å
219G91.8Very high95.4Very high9 Ų948.9 Ų48.99%0.09328%0.275CS..  trans-77.5-168.4170.400000112.6E221 G222 G223G219-E221 PolarHBondContact O-N 3.02Å; G219-E221 VanDerWaalsContact O-N 3.11Å; G219-G222 PolarHBondContact O-N 3.46Å; G219-G222 VanDerWaalsContact O-N 3.17Å; G219-G223 PolarHBondContact N-O 3.28Å
220D90.4Very high95.2Very high50 Ų5050.2 Ų50.227%0.26727%0.266SS..THydrogen-bonded Turntrans-55.6-32.8-176.3-77.5-6.2000113.1R26 R411 R414R26-D220 WeakPolarHBondContact CD-OD2 3.37Å; D220-R411 PolarHBondContact O-NE 3.29Å; D220-R414 PolarHBondContact O-NH2 3.25Å
221E95.9Very high95Very high3 Ų344.9 Ų44.91%0.01424%0.243CC..THydrogen-bonded Turntrans-104.99.4-173.7-57.7-174.1171.200114.4N162 H169 G219 G223 H382 S384 A408N162-E221 PolarHBondContact ND2-OE2 2.93Å; H169-E221 IonicContact CE1-OE1 3.63Å; H169-E221 PolarHBondContact CE1-OE1 2.87Å; H169-E221 IonicContact ND1-OE1 3.65Å; G219-E221 PolarHBondContact O-N 3.02Å; G219-E221 VanDerWaalsContact O-N 3.11Å; E221-G223 VanDerWaalsContact C-N 3.34Å; E221-G223 PolarHBondContact O-N 3.01Å; E221-H382 IonicContact OE1-CE1 3.63Å; E221-H382 IonicContact OE1-NE2 2.71Å; E221-H382 PolarHBondContact OE1-NE2 2.88Å; E221-H382 IonicContact OE2-CE1 2.68Å; E221-H382 PolarHBondContact OE2-CE1 3.01Å; E221-H382 IonicContact OE2-NE2 3.77Å; E221-H382 PolarHBondContact OE2-NE2 2.92Å; E221-S384 WeakPolarHBondContact OE1-CA 3.45Å; E221-A408 WeakPolarHBondContact O-CB 3.15Å; E221-A408 PolarHBondContact O-N 3.18Å
222G97.3Very high94.9Very high0 Ų044.8 Ų44.80%025%0.247CC..SBendtrans87.5-7.9174.400000115.1Y200 V218 G219 A408Y200-G222 WeakPolarHBondContact CE2-O 3.36Å; Y200-G222 PolarHBondContact OH-O 2.77Å; V218-G222 WeakPolarHBondContact CG1-O 3.23Å; G219-G222 PolarHBondContact O-N 3.46Å; G219-G222 VanDerWaalsContact O-N 3.17Å; G222-A408 WeakPolarHBondContact O-CB 3.35Å
223G97.9Very high94.9Very high0 Ų045.8 Ų45.80%024%0.243CC..  trans-74.2158.217100000111.6V163 N165 V218 G219 E221V163-G223 CarbonylContact O-C 3.57Å; V163-G223 WeakPolarHBondContact O-CA 2.87Å; N165-G223 WeakPolarHBondContact OD1-CA 3.27Å; N165-G223 PolarHBondContact OD1-N 3.44Å; V218-G223 CarbonylContact C-O 3.55Å; V218-G223 WeakPolarHBondContact CA-O 3.35Å; G219-G223 PolarHBondContact N-O 3.28Å; E221-G223 VanDerWaalsContact C-N 3.34Å; E221-G223 PolarHBondContact O-N 3.01Å
224F98.4Very high95Very high0 Ų039 Ų390%021%0.213CC..BIsolated β-bridgetrans-73150.2-177.5-59.4-65.1000111.6V163 I164 N165 Y200 L203 K204 I207 T216 V218 P226V163-F224 PolarHBondContact O-N 3.1Å; I164-F224 CarbonylContact C-O 3.5Å; I164-F224 WeakPolarHBondContact CA-O 3.32Å; N165-F224 PolarHBondContact N-O 2.9Å; Y200-F224 HydrophobicContact CD1-CZ 4.3Å; Y200-F224 HydrophobicContact CD2-CD2 4.42Å; Y200-F224 AromaticContact CD2-CE2 3.66Å; Y200-F224 HydrophobicContact CD2-CE2 3.66Å; Y200-F224 HydrophobicContact CD2-CZ 4.1Å; Y200-F224 HydrophobicContact CE1-CE2 4.27Å; Y200-F224 AromaticContact CE1-CZ 3.71Å; Y200-F224 HydrophobicContact CE1-CZ 3.71Å; Y200-F224 AromaticContact CE2-CD2 4Å; Y200-F224 HydrophobicContact CE2-CD2 4Å; Y200-F224 HydrophobicContact CE2-CE1 4.28Å; Y200-F224 AromaticContact CE2-CE2 3.38Å; Y200-F224 HydrophobicContact CE2-CE2 3.38Å; Y200-F224 AromaticContact CE2-CZ 3.52Å; Y200-F224 HydrophobicContact CE2-CZ 3.52Å; Y200-F224 HydrophobicContact CG-CE2 4.25Å; Y200-F224 HydrophobicContact CG-CZ 4.47Å; Y200-F224 AromaticContact CZ-CE1 3.89Å; Y200-F224 AromaticContact CZ-CE2 3.71Å; Y200-F224 AromaticContact CZ-CZ 3.29Å; Y200-F224 WeakPolarHBondContact O-CE2 3.31Å; Y200-F224 WeakPolarHBondContact OH-CZ 3.31Å; L203-F224 HydrophobicContact CB-CE2 4.33Å; L203-F224 HydrophobicContact CD2-CD2 3.87Å; L203-F224 HydrophobicContact CD2-CE2 4.23Å; L203-F224 HydrophobicContact CG-CD2 3.94Å; L203-F224 HydrophobicContact CG-CE2 4.18Å; K204-F224 HydrophobicContact CB-CE1 4.03Å; K204-F224 HydrophobicContact CB-CE2 3.85Å; K204-F224 HydrophobicContact CB-CZ 3.36Å; K204-F224 HydrophobicContact CD-CE1 4.08Å; K204-F224 HydrophobicContact CD-CZ 3.99Å; K204-F224 HydrophobicContact CG-CE1 3.74Å; K204-F224 HydrophobicContact CG-CE2 4.47Å; K204-F224 HydrophobicContact CG-CZ 3.6Å; I207-F224 HydrophobicContact CD1-CB 3.52Å; I207-F224 HydrophobicContact CD1-CD2 3.68Å; I207-F224 HydrophobicContact CD1-CG 3.78Å; T216-F224 WeakPolarHBondContact O-CD1 3.49Å; T216-F224 WeakPolarHBondContact O-CE1 3.36Å; V218-F224 HydrophobicContact CG1-CD1 4.15Å; V218-F224 HydrophobicContact CG1-CE1 4.18Å; F224-P226 VanDerWaalsContact O-CD 3.22Å; F224-P226 WeakPolarHBondContact O-CD 3.46Å
225A96.1Very high95.1Very high28 Ų2833.6 Ų33.623%0.23118%0.184CC..  trans-11763.3177.600000111.6A170 N217A170-A225 HydrophobicContact CB-CB 3.77Å; N217-A225 PolarHBondContact O-N 2.96Å
226P95Very high95.2Very high0 Ų036.2 Ų36.20%019%0.194CC..  trans-63.2147.8176.729.8-34.3000110.3I164 N172 I207 Y211 A215 F224 I228 L237I164-P226 HydrophobicContact CG2-CG 4.12Å; N172-P226 VanDerWaalsContact CB-O 3.23Å; N172-P226 WeakPolarHBondContact CB-O 3.48Å; N172-P226 PolarHBondContact ND2-O 2.94Å; I207-P226 HydrophobicContact CD1-CG 4.26Å; I207-P226 HydrophobicContact CG2-CB 4.13Å; Y211-P226 HydrophobicContact CD2-CB 4.15Å; Y211-P226 HydrophobicContact CE2-CB 4.39Å; A215-P226 HydrophobicContact CB-CB 4.42Å; F224-P226 VanDerWaalsContact O-CD 3.22Å; F224-P226 WeakPolarHBondContact O-CD 3.46Å; P226-I228 HydrophobicContact CB-CG2 4.3Å; P226-I228 HydrophobicContact CG-CD1 3.98Å; P226-I228 HydrophobicContact CG-CG1 4.12Å; P226-I228 PolarHBondContact O-N 2.83Å; P226-L237 HydrophobicContact CG-CD1 4.45Å
227N91.8Very high95.3Very high120 Ų12035.5 Ų35.564%0.64219%0.189SC*.SBendtrans-79.468.9179.1-170.933.5000111.2
228I92.9Very high95.4Very high3 Ų330.2 Ų30.22%0.01516%0.161CC..  trans-111.4151.5176.460177.5000109.6K173 L174 Y211 P226 E233 A234 L237K173-I228 CarbonylContact C-O 3.56Å; L174-I228 WeakPolarHBondContact CA-O 3.43Å; L174-I228 HydrophobicContact CB-CG1 4.3Å; L174-I228 HydrophobicContact CD1-CD1 4.25Å; L174-I228 HydrophobicContact CD1-CG1 4.19Å; L174-I228 HydrophobicContact CD2-CD1 4.07Å; L174-I228 HydrophobicContact CD2-CG1 4.17Å; L174-I228 HydrophobicContact CG-CG1 4.49Å; L174-I228 PolarHBondContact N-O 2.98Å; Y211-I228 HydrophobicContact CE1-CG2 3.7Å; Y211-I228 HydrophobicContact CE2-CG2 4.22Å; Y211-I228 WeakPolarHBondContact OH-CG2 3.43Å; P226-I228 HydrophobicContact CB-CG2 4.3Å; P226-I228 HydrophobicContact CG-CD1 3.98Å; P226-I228 HydrophobicContact CG-CG1 4.12Å; P226-I228 PolarHBondContact O-N 2.83Å; I228-E233 HydrophobicContact CG2-CG 4.07Å; I228-E233 WeakPolarHBondContact CG2-OE2 3.38Å; I228-A234 HydrophobicContact CD1-CB 3.72Å; I228-L237 HydrophobicContact CD1-CD1 4.26Å
229L91.4Very high95.5Very high56 Ų5631.2 Ų31.229%0.29316%0.161SC..  trans-105.1-47.1174.9173.263.4000110.5K173 N231 D271K173-L229 HydrophobicContact CB-CB 4.08Å; K173-L229 HydrophobicContact CB-CD1 3.81Å; K173-L229 HydrophobicContact CD-CD1 4.41Å; L229-N231 PolarHBondContact O-N 3.34Å; L229-D271 HydrophobicContact CD1-CB 3.87Å; L229-D271 WeakPolarHBondContact CD1-OD1 3.23Å
230E93.3Very high95.8Very high117 Ų11733.1 Ų33.155%0.54717%0.171SC..  trans-74.5122.3-173.9-62.5-58.4148.100112N232 E233E230-N232 PolarHBondContact O-N 3.05Å; E230-E233 HydrophobicContact CB-CB 4.2Å; E230-E233 VanDerWaalsContact O-CB 3.29Å; E230-E233 WeakPolarHBondContact O-CB 3.28Å; E230-E233 PolarHBondContact O-N 2.88Å
231N92Very high96.2Very high5 Ų530.7 Ų30.73%0.02716%0.158CC..Hα-helixtrans-61.1-31.3177.8-57.1-68.4000112.4L174 M176 F179 L229 E233 A234 L235 F294L174-N231 HydrophobicContact CD1-CB 4.37Å; L174-N231 VanDerWaalsContact CD1-OD1 3.24Å; L174-N231 WeakPolarHBondContact CD1-OD1 3.5Å; M176-N231 WeakPolarHBondContact CB-OD1 3.49Å; M176-N231 HydrophobicContact CE-CB 4.07Å; M176-N231 HydrophobicContact CG-CB 4.43Å; M176-N231 WeakPolarHBondContact CG-OD1 3.18Å; M176-N231 PolarHBondContact N-OD1 2.95Å; M176-N231 HydrophobicContact SD-CB 3.67Å; F179-N231 HydrophobicContact CE1-CB 4.44Å; F179-N231 HydrophobicContact CZ-CB 4Å; L229-N231 PolarHBondContact O-N 3.34Å; N231-E233 PolarHBondContact O-N 3.31Å; N231-A234 WeakPolarHBondContact O-CB 3.19Å; N231-A234 PolarHBondContact O-N 3.28Å; N231-L235 PolarHBondContact O-N 2.87Å; N231-F294 HydrophobicContact CB-CE2 4.07Å; N231-F294 HydrophobicContact CB-CZ 3.86Å
232N95.1Very high96.3Very high63 Ų6330.9 Ų30.934%0.33716%0.159SC..Hα-helixtrans-62.4-32.8174.7-162.372000112.5E230 A234 L235 E236 F294 Y298E230-N232 PolarHBondContact O-N 3.05Å; N232-A234 VanDerWaalsContact C-N 3.33Å; N232-L235 PolarHBondContact O-N 3.48Å; N232-E236 PolarHBondContact O-N 3.3Å; N232-F294 HydrophobicContact CB-CE1 4.09Å; N232-Y298 PolarHBondContact ND2-OH 2.92Å; N232-Y298 WeakPolarHBondContact OD1-CE2 3.33Å; N232-Y298 PolarHBondContact OD1-OH 3.07Å
233E96.8Very high96.4Very high53 Ų5336 Ų3625%0.24818%0.183CC..Hα-helixtrans-68.1-35.4178.7-172.6167-15500111.5K210 Y211 I228 E230 N231 E236 L237K210-E233 WeakPolarHBondContact CE-OE1 3.46Å; K210-E233 IonicContact NZ-OE1 2.7Å; K210-E233 PolarHBondContact NZ-OE1 3.45Å; Y211-E233 VanDerWaalsContact OH-CG 3.31Å; Y211-E233 WeakPolarHBondContact OH-CG 3.3Å; Y211-E233 PolarHBondContact OH-OE1 2.94Å; I228-E233 HydrophobicContact CG2-CG 4.07Å; I228-E233 WeakPolarHBondContact CG2-OE2 3.38Å; E230-E233 HydrophobicContact CB-CB 4.2Å; E230-E233 VanDerWaalsContact O-CB 3.29Å; E230-E233 WeakPolarHBondContact O-CB 3.28Å; E230-E233 PolarHBondContact O-N 2.88Å; N231-E233 PolarHBondContact O-N 3.31Å; E233-E236 PolarHBondContact O-N 2.96Å; E233-L237 VanDerWaalsContact O-CG 3.28Å; E233-L237 WeakPolarHBondContact O-CG 3.5Å; E233-L237 PolarHBondContact O-N 3.07Å
234A97.6Very high96.4Very high0 Ų042.3 Ų42.30%021%0.211CC..Hα-helixtrans-62-45.2172.700000111.3I164 L174 F179 I228 N231 N232 E236 L237 L238I164-A234 HydrophobicContact CD1-CB 4.13Å; I164-A234 HydrophobicContact CG2-CB 4.45Å; L174-A234 HydrophobicContact CD1-CB 4.47Å; L174-A234 HydrophobicContact CD2-CB 4.31Å; F179-A234 HydrophobicContact CD1-CB 3.75Å; F179-A234 HydrophobicContact CD2-CB 4Å; F179-A234 HydrophobicContact CE1-CB 3.62Å; F179-A234 HydrophobicContact CE2-CB 3.92Å; F179-A234 HydrophobicContact CG-CB 3.93Å; F179-A234 HydrophobicContact CZ-CB 3.71Å; I228-A234 HydrophobicContact CD1-CB 3.72Å; N231-A234 WeakPolarHBondContact O-CB 3.19Å; N231-A234 PolarHBondContact O-N 3.28Å; N232-A234 VanDerWaalsContact C-N 3.33Å; A234-E236 VanDerWaalsContact C-N 3.35Å; A234-E236 PolarHBondContact O-N 3.02Å; A234-L237 WeakPolarHBondContact O-CB 3.47Å; A234-L237 PolarHBondContact O-N 2.79Å; A234-L238 WeakPolarHBondContact O-CG 3.46Å; A234-L238 PolarHBondContact O-N 3.31Å
235L98.3Very high96.4Very high0 Ų043.1 Ų43.10%022%0.217CC..Hα-helixtrans-62.6-38.9177.5-66.1173000112.4F179 N231 N232 L238 K239 I253 M255 F294 Y298 V300F179-L235 HydrophobicContact CD1-CD2 3.85Å; F179-L235 HydrophobicContact CD1-CG 4.17Å; F179-L235 HydrophobicContact CE1-CD2 4.19Å; F179-L235 HydrophobicContact CE1-CG 4.07Å; N231-L235 PolarHBondContact O-N 2.87Å; N232-L235 PolarHBondContact O-N 3.48Å; L235-L238 PolarHBondContact O-N 2.88Å; L235-K239 WeakPolarHBondContact O-CB 3.26Å; L235-K239 PolarHBondContact O-N 2.98Å; L235-I253 HydrophobicContact CD2-CD1 4.19Å; L235-I253 HydrophobicContact CD2-CG2 3.81Å; L235-M255 HydrophobicContact CD1-SD 4.36Å; L235-M255 HydrophobicContact CD2-SD 4.1Å; L235-F294 HydrophobicContact CD1-CB 3.79Å; L235-F294 HydrophobicContact CD1-CD1 3.75Å; L235-F294 HydrophobicContact CD1-CD2 3.9Å; L235-F294 HydrophobicContact CD1-CE1 4.29Å; L235-F294 HydrophobicContact CD1-CE2 4.41Å; L235-F294 HydrophobicContact CD1-CG 3.55Å; L235-Y298 HydrophobicContact CB-CD1 3.8Å; L235-Y298 HydrophobicContact CB-CD2 3.89Å; L235-Y298 HydrophobicContact CB-CE1 3.84Å; L235-Y298 HydrophobicContact CB-CE2 3.93Å; L235-Y298 HydrophobicContact CB-CG 3.84Å; L235-Y298 HydrophobicContact CD1-CD2 3.54Å; L235-Y298 HydrophobicContact CD1-CE2 3.89Å; L235-Y298 HydrophobicContact CD1-CG 4.11Å; L235-Y298 HydrophobicContact CG-CD2 4.27Å; L235-Y298 HydrophobicContact CG-CG 4.43Å; L235-V300 HydrophobicContact CD2-CG2 4.03Å
236E98.2Very high96.5Very high69 Ų6944.3 Ų44.332%0.32223%0.232SC..Hα-helixtrans-67.4-36.6175-74.3-57.517200113.7N232 E233 A234 L238 K239 T240 Y298N232-E236 PolarHBondContact O-N 3.3Å; E233-E236 PolarHBondContact O-N 2.96Å; A234-E236 VanDerWaalsContact C-N 3.35Å; A234-E236 PolarHBondContact O-N 3.02Å; E236-L238 VanDerWaalsContact C-N 3.32Å; E236-K239 PolarHBondContact O-N 2.81Å; E236-T240 WeakPolarHBondContact O-CB 3.43Å; E236-T240 PolarHBondContact O-N 3.02Å; E236-T240 PolarHBondContact O-OG1 3.49Å; E236-Y298 VanDerWaalsContact CD-CE1 3.44Å; E236-Y298 HydrophobicContact CG-CE1 4.04Å; E236-Y298 WeakPolarHBondContact CG-OH 3.33Å; E236-Y298 VanDerWaalsContact OE1-CE1 3.26Å; E236-Y298 WeakPolarHBondContact OE1-CE1 3.37Å; E236-Y298 VanDerWaalsContact OE1-CZ 3.3Å; E236-Y298 PolarHBondContact OE1-OH 3.43Å
237L98.4Very high96.7Very high5 Ų545.8 Ų45.83%0.02624%0.238CC..Hα-helixtrans-62-42.7173.2-68.3168.3000110.9I164 L203 V206 I207 K210 Y211 P226 I228 E233 A234 A241I164-L237 HydrophobicContact CD1-CB 4.15Å; I164-L237 HydrophobicContact CD1-CD1 4.41Å; L203-L237 HydrophobicContact CD1-CB 3.98Å; V206-L237 HydrophobicContact CG1-CD2 3.7Å; I207-L237 HydrophobicContact CG1-CD1 4.34Å; K210-L237 HydrophobicContact CD-CD2 4.2Å; Y211-L237 HydrophobicContact CE2-CD1 3.79Å; Y211-L237 HydrophobicContact CE2-CD2 3.9Å; Y211-L237 HydrophobicContact CE2-CG 4.45Å; P226-L237 HydrophobicContact CG-CD1 4.45Å; I228-L237 HydrophobicContact CD1-CD1 4.26Å; E233-L237 VanDerWaalsContact O-CG 3.28Å; E233-L237 WeakPolarHBondContact O-CG 3.5Å; E233-L237 PolarHBondContact O-N 3.07Å; A234-L237 WeakPolarHBondContact O-CB 3.47Å; A234-L237 PolarHBondContact O-N 2.79Å; L237-A241 WeakPolarHBondContact O-CB 3.39Å; L237-A241 PolarHBondContact O-N 2.97Å
238L98.3Very high96.9Very high0 Ų043.4 Ų43.40%023%0.229CC..Hα-helixtrans-63.6-49.7176-67.6-167.8000112V163 I164 F179 I181 L203 A234 L235 E236 T240 A241 I242 I253V163-L238 HydrophobicContact CG2-CD1 4.38Å; V163-L238 HydrophobicContact CG2-CD2 3.45Å; V163-L238 VanDerWaalsContact CG2-CD2 3.45Å; I164-L238 HydrophobicContact CD1-CD2 3.71Å; I164-L238 HydrophobicContact CD1-CG 3.97Å; I164-L238 HydrophobicContact CG1-CD2 4.01Å; F179-L238 HydrophobicContact CB-CD1 3.79Å; I181-L238 HydrophobicContact CG2-CD1 4.26Å; I181-L238 HydrophobicContact CG2-CD2 4.39Å; L203-L238 HydrophobicContact CD1-CD2 4.11Å; L203-L238 HydrophobicContact CD2-CD2 3.65Å; L203-L238 HydrophobicContact CG-CD2 4.5Å; A234-L238 WeakPolarHBondContact O-CG 3.46Å; A234-L238 PolarHBondContact O-N 3.31Å; L235-L238 PolarHBondContact O-N 2.88Å; E236-L238 VanDerWaalsContact C-N 3.32Å; L238-T240 VanDerWaalsContact C-N 3.31Å; L238-T240 PolarHBondContact O-N 2.87Å; L238-A241 PolarHBondContact O-N 3.03Å; L238-A241 VanDerWaalsContact O-N 3.1Å; L238-I242 WeakPolarHBondContact O-CB 3.42Å; L238-I242 WeakPolarHBondContact O-CD1 3.4Å; L238-I242 WeakPolarHBondContact O-CG1 3.48Å; L238-I242 PolarHBondContact O-N 2.95Å; L238-I253 HydrophobicContact CB-CD1 4.02Å; L238-I253 HydrophobicContact CD1-CD1 4.19Å; L238-I253 HydrophobicContact CD1-CG1 4.35Å; L238-I253 HydrophobicContact CD1-CG2 4.24Å
239K98.1Very high97.1Very high75 Ų7550.5 Ų50.533%0.32627%0.267SS..Hα-helixtrans-54.4-49.4177.2-178.6-178.6172.8-173.80111.3L235 E236 A241 I242 E243 Y298L235-K239 WeakPolarHBondContact O-CB 3.26Å; L235-K239 PolarHBondContact O-N 2.98Å; E236-K239 PolarHBondContact O-N 2.81Å; K239-A241 VanDerWaalsContact C-N 3.33Å; K239-A241 PolarHBondContact O-N 2.87Å; K239-I242 PolarHBondContact O-N 2.68Å; K239-E243 WeakPolarHBondContact CE-OE1 3.12Å; K239-E243 WeakPolarHBondContact O-CB 3.45Å; K239-E243 WeakPolarHBondContact O-CG 3.37Å; K239-E243 PolarHBondContact O-N 2.84Å; K239-Y298 HydrophobicContact CD-CD1 4.38Å; K239-Y298 HydrophobicContact CD-CE1 4.38Å
240T98.4Very high97.4Very high48 Ų4850.9 Ų50.929%0.29427%0.266SS..Hα-helixtrans-59.6-42.3177.2-57.60000111.9V206 E236 L238 K244V206-T240 HydrophobicContact CG1-CG2 4.18Å; V206-T240 HydrophobicContact CG2-CG2 4.03Å; E236-T240 WeakPolarHBondContact O-CB 3.43Å; E236-T240 PolarHBondContact O-N 3.02Å; E236-T240 PolarHBondContact O-OG1 3.49Å; L238-T240 VanDerWaalsContact C-N 3.31Å; L238-T240 PolarHBondContact O-N 2.87Å; T240-K244 HydrophobicContact CG2-CD 4.25Å; T240-K244 WeakPolarHBondContact O-CB 3.48Å; T240-K244 VanDerWaalsContact O-CG 3.3Å; T240-K244 WeakPolarHBondContact O-CG 3.41Å; T240-K244 PolarHBondContact O-N 3.46Å
241A98.6Very high97.7Very high0 Ų045.6 Ų45.60%024%0.242CC..Hα-helixtrans-68.3-40.818000000112.6V199 L203 L237 L238 K239 K244 A245V199-A241 HydrophobicContact CG1-CB 4.22Å; L203-A241 HydrophobicContact CB-CB 3.67Å; L203-A241 HydrophobicContact CD1-CB 3.94Å; L203-A241 HydrophobicContact CG-CB 4.4Å; L237-A241 WeakPolarHBondContact O-CB 3.39Å; L237-A241 PolarHBondContact O-N 2.97Å; L238-A241 PolarHBondContact O-N 3.03Å; L238-A241 VanDerWaalsContact O-N 3.1Å; K239-A241 VanDerWaalsContact C-N 3.33Å; K239-A241 PolarHBondContact O-N 2.87Å; A241-K244 PolarHBondContact O-N 3.32Å; A241-A245 WeakPolarHBondContact O-CB 3.31Å; A241-A245 PolarHBondContact O-N 2.87Å
242I98.6Very high98Very high7 Ų746.5 Ų46.54%0.03625%0.246CC..Hα-helixtrans-62.4-46.5176.2-68.7163.1000110.3I181 V199 L238 K239 A245 G246 Y247 I251 I253I181-I242 HydrophobicContact CG2-CD1 4.15Å; I181-I242 HydrophobicContact CG2-CG1 4.48Å; V199-I242 HydrophobicContact CG1-CG1 3.89Å; V199-I242 HydrophobicContact CG2-CG1 4.47Å; L238-I242 WeakPolarHBondContact O-CB 3.42Å; L238-I242 WeakPolarHBondContact O-CD1 3.4Å; L238-I242 WeakPolarHBondContact O-CG1 3.48Å; L238-I242 PolarHBondContact O-N 2.95Å; K239-I242 PolarHBondContact O-N 2.68Å; I242-A245 PolarHBondContact O-N 2.87Å; I242-G246 PolarHBondContact O-N 3.43Å; I242-Y247 WeakPolarHBondContact CG2-O 3.35Å; I242-Y247 PolarHBondContact O-N 3.06Å; I242-Y247 VanDerWaalsContact O-N 3.13Å; I242-I251 HydrophobicContact CD1-CB 4.33Å; I242-I251 HydrophobicContact CD1-CG2 3.66Å; I242-I251 HydrophobicContact CG1-CB 4.48Å; I242-I251 HydrophobicContact CG1-CD1 4.12Å; I242-I251 HydrophobicContact CG1-CG2 4.11Å; I242-I251 HydrophobicContact CG2-CB 4.26Å; I242-I251 HydrophobicContact CG2-CD1 4.27Å; I242-I253 HydrophobicContact CD1-CD1 4.41Å; I242-I253 HydrophobicContact CD1-CG1 4.32Å
243E98.4Very high98.2Very high106 Ų10643.5 Ų43.550%0.49523%0.23SC..Hα-helixtrans-61.3-46.8176.6-73.9172.7-177.200111.4K239 A245 G246K239-E243 WeakPolarHBondContact CE-OE1 3.12Å; K239-E243 WeakPolarHBondContact O-CB 3.45Å; K239-E243 WeakPolarHBondContact O-CG 3.37Å; K239-E243 PolarHBondContact O-N 2.84Å; E243-A245 VanDerWaalsContact C-N 3.29Å; E243-A245 PolarHBondContact O-N 3.29Å; E243-G246 PolarHBondContact O-N 3.28Å
244K98.5Very high98.3Very high134 Ų13441 Ų4158%0.58322%0.218SC*.Hα-helixtrans-63.6-32.5178.2-77.8-176.2177.6-168.50113.7V206 T240 A241V206-K244 HydrophobicContact CG2-CD 3.76Å; T240-K244 HydrophobicContact CG2-CD 4.25Å; T240-K244 WeakPolarHBondContact O-CB 3.48Å; T240-K244 VanDerWaalsContact O-CG 3.3Å; T240-K244 WeakPolarHBondContact O-CG 3.41Å; T240-K244 PolarHBondContact O-N 3.46Å; A241-K244 PolarHBondContact O-N 3.32Å
245A98.5Very high98.3Very high16 Ų1641 Ų4113%0.13222%0.218CC..Hα-helixtrans-77-11.4175.300000113V199 N202 A241 I242 E243 Y247V199-A245 HydrophobicContact CB-CB 4.44Å; V199-A245 HydrophobicContact CG2-CB 3.58Å; N202-A245 HydrophobicContact CB-CB 4.43Å; A241-A245 WeakPolarHBondContact O-CB 3.31Å; A241-A245 PolarHBondContact O-N 2.87Å; I242-A245 PolarHBondContact O-N 2.87Å; E243-A245 VanDerWaalsContact C-N 3.29Å; E243-A245 PolarHBondContact O-N 3.29Å; A245-Y247 HydrophobicContact CB-CD2 3.68Å; A245-Y247 HydrophobicContact CB-CE2 4.07Å; A245-Y247 WeakPolarHBondContact O-CD2 3.38Å; A245-Y247 VanDerWaalsContact O-CE2 3.27Å; A245-Y247 WeakPolarHBondContact O-CE2 3.19Å
246G98.5Very high98.3Very high53 Ų5341 Ų4155%0.54622%0.218SC..THydrogen-bonded Turntrans81.425.2179.400000114.4I242 E243I242-G246 PolarHBondContact O-N 3.43Å; E243-G246 PolarHBondContact O-N 3.28Å
247Y98.3Very high98.4Very high32 Ų3237.7 Ų37.713%0.12520%0.203CC..  trans-121.134.8-177.2-57.5-58.9000116.2I195 E198 V199 I242 A245 D249 K250I195-Y247 HydrophobicContact CB-CD2 4.46Å; I195-Y247 HydrophobicContact CB-CE2 4.41Å; I195-Y247 HydrophobicContact CD1-CD1 4.27Å; I195-Y247 HydrophobicContact CD1-CE1 4.25Å; I195-Y247 HydrophobicContact CG1-CD1 4.1Å; I195-Y247 HydrophobicContact CG1-CD2 4.41Å; I195-Y247 HydrophobicContact CG1-CE1 3.82Å; I195-Y247 HydrophobicContact CG1-CE2 4.16Å; I195-Y247 HydrophobicContact CG1-CG 4.39Å; I195-Y247 HydrophobicContact CG2-CD1 4.39Å; I195-Y247 HydrophobicContact CG2-CD2 3.83Å; I195-Y247 HydrophobicContact CG2-CE2 4.26Å; I195-Y247 HydrophobicContact CG2-CG 3.9Å; E198-Y247 HydrophobicContact CB-CE2 4.15Å; E198-Y247 WeakPolarHBondContact OE2-CE2 3.37Å; E198-Y247 VanDerWaalsContact OE2-CZ 3.26Å; E198-Y247 PolarHBondContact OE2-OH 3.07Å; V199-Y247 HydrophobicContact CG2-CD2 4.03Å; I242-Y247 WeakPolarHBondContact CG2-O 3.35Å; I242-Y247 PolarHBondContact O-N 3.06Å; I242-Y247 VanDerWaalsContact O-N 3.13Å; A245-Y247 HydrophobicContact CB-CD2 3.68Å; A245-Y247 HydrophobicContact CB-CE2 4.07Å; A245-Y247 WeakPolarHBondContact O-CD2 3.38Å; A245-Y247 VanDerWaalsContact O-CE2 3.27Å; A245-Y247 WeakPolarHBondContact O-CE2 3.19Å; Y247-D249 PolarHBondContact O-N 2.65Å; Y247-K250 HydrophobicContact CD1-CD 4.17Å; Y247-K250 PolarHBondContact O-N 2.92Å; Y247-K250 VanDerWaalsContact O-N 3.17Å
248P96.9Very high98.3Very high70 Ų7037.6 Ų37.646%0.45520%0.203SC..THydrogen-bonded Turntrans-60.1-31.4-176.427.9-35.6000113.6
249D96.9Very high98.3Very high151 Ų15137.6 Ų37.681%0.80720%0.203SC*.THydrogen-bonded Turntrans-94.2-2.3-177.2-54.8-52.6000113.9Y247Y247-D249 PolarHBondContact O-N 2.65Å
250K98.3Very high98.3Very high65 Ų6534.9 Ų34.928%0.28319%0.193SC..THydrogen-bonded Turntrans-107.9-14.2-176.1-71-164.9173.2-177.30114.2P183 V184 G185 E191 I195 Y247P183-K250 CarbonylContact C-O 3.26Å; P183-K250 VanDerWaalsContact C-O 3.28Å; P183-K250 WeakPolarHBondContact CA-O 3.38Å; V184-K250 PolarHBondContact N-O 3.05Å; V184-K250 VanDerWaalsContact N-O 3.13Å; G185-K250 PolarHBondContact N-O 3.08Å; E191-K250 IonicContact OE1-NZ 2.78Å; E191-K250 PolarHBondContact OE1-NZ 2.81Å; I195-K250 HydrophobicContact CD1-CD 3.66Å; Y247-K250 HydrophobicContact CD1-CD 4.17Å; Y247-K250 PolarHBondContact O-N 2.92Å; Y247-K250 VanDerWaalsContact O-N 3.17Å
251I98.6Very high98.1Very high6 Ų635.3 Ų35.33%0.03119%0.192CC..  trans-120134.5-171.8-65.6175000110.6I181 L182 P183 I195 V199 I242I181-I251 HydrophobicContact CB-CG2 3.83Å; I181-I251 HydrophobicContact CG2-CG2 4.12Å; L182-I251 WeakPolarHBondContact O-CA 2.89Å; P183-I251 HydrophobicContact CB-CG1 4.31Å; I195-I251 HydrophobicContact CG2-CD1 3.61Å; I195-I251 HydrophobicContact CG2-CG1 3.9Å; V199-I251 HydrophobicContact CB-CD1 4.42Å; V199-I251 HydrophobicContact CG2-CD1 3.47Å; V199-I251 VanDerWaalsContact CG2-CD1 3.47Å; I242-I251 HydrophobicContact CD1-CB 4.33Å; I242-I251 HydrophobicContact CD1-CG2 3.66Å; I242-I251 HydrophobicContact CG1-CB 4.48Å; I242-I251 HydrophobicContact CG1-CD1 4.12Å; I242-I251 HydrophobicContact CG1-CG2 4.11Å; I242-I251 HydrophobicContact CG2-CB 4.26Å; I242-I251 HydrophobicContact CG2-CD1 4.27Å
252I98.8Very high98.1Very high24 Ų2435.4 Ų35.412%0.12319%0.192CC..EExtended strand (participates in β ladder)trans-108.3163.3162.264.9176.6000109L182 V184 P299 Q301 F439L182-I252 HydrophobicContact CB-CD1 4.21Å; L182-I252 HydrophobicContact CB-CG1 3.67Å; L182-I252 HydrophobicContact CD2-CD1 4.29Å; L182-I252 HydrophobicContact CG-CG1 4.47Å; L182-I252 PolarHBondContact N-O 3.43Å; L182-I252 PolarHBondContact O-N 2.91Å; V184-I252 HydrophobicContact CG1-CD1 3.52Å; V184-I252 HydrophobicContact CG1-CG1 3.87Å; V184-I252 HydrophobicContact CG2-CD1 4.28Å; V184-I252 HydrophobicContact CG2-CG1 4.12Å; V184-I252 HydrophobicContact CG2-CG2 3.82Å; I252-P299 WeakPolarHBondContact CA-O 3.35Å; I252-Q301 HydrophobicContact CB-CB 4.01Å; I252-Q301 HydrophobicContact CB-CG 3.88Å; I252-Q301 HydrophobicContact CD1-CB 3.65Å; I252-Q301 HydrophobicContact CD1-CG 4.27Å; I252-Q301 HydrophobicContact CG1-CB 4.24Å; I252-Q301 HydrophobicContact CG2-CB 4.37Å; I252-Q301 HydrophobicContact CG2-CG 3.82Å; I252-F439 HydrophobicContact CD1-CE1 3.73Å; I252-F439 HydrophobicContact CD1-CZ 3.89Å
253I98.9Very high98Very high0 Ų037.7 Ų37.70%020%0.202CC..EExtended strand (participates in β ladder)trans-103.3136.6177-65.6173.4000109.6M180 L235 L238 I242 M255 P299 V300 Q301M180-I253 VanDerWaalsContact O-CA 3.32Å; M180-I253 WeakPolarHBondContact O-CA 3.41Å; M180-I253 WeakPolarHBondContact O-CG2 3.48Å; L235-I253 HydrophobicContact CD2-CD1 4.19Å; L235-I253 HydrophobicContact CD2-CG2 3.81Å; L238-I253 HydrophobicContact CB-CD1 4.02Å; L238-I253 HydrophobicContact CD1-CD1 4.19Å; L238-I253 HydrophobicContact CD1-CG1 4.35Å; L238-I253 HydrophobicContact CD1-CG2 4.24Å; I242-I253 HydrophobicContact CD1-CD1 4.41Å; I242-I253 HydrophobicContact CD1-CG1 4.32Å; I253-M255 HydrophobicContact CG2-CG 4.31Å; I253-P299 HydrophobicContact CD1-CG 4.17Å; I253-P299 HydrophobicContact CG1-CG 4.24Å; I253-P299 PolarHBondContact N-O 3.12Å; I253-V300 HydrophobicContact CB-CG2 4.09Å; I253-V300 HydrophobicContact CG2-CG2 3.95Å; I253-V300 WeakPolarHBondContact O-CA 3.44Å; I253-Q301 PolarHBondContact O-N 3.49Å
254G98.8Very high97.9Very high0 Ų036.3 Ų36.30%019%0.192CC..EExtended strand (participates in β ladder)trans-110.2154.5165.800000110M180 S302M180-G254 WeakPolarHBondContact CA-O 3.41Å; M180-G254 PolarHBondContact N-O 3.17Å; M180-G254 PolarHBondContact O-N 2.93Å; G254-S302 CarbonylContact C-O 3.4Å; G254-S302 VanDerWaalsContact CA-O 3.28Å; G254-S302 WeakPolarHBondContact CA-O 3.42Å
255M98.8Very high97.6Very high0 Ų037.4 Ų37.40%020%0.204CC..EExtended strand (participates in β ladder)trans-133.9137.6175-61.6174.361.100109.1M176 E178 F179 L235 I253 F294 V300 S302 I303 E304M176-M255 HydrophobicContact SD-CE 3.28Å; M176-M255 WeakPolarHBondContact SD-CE 3.33Å; E178-M255 WeakPolarHBondContact O-CA 3.38Å; F179-M255 HydrophobicContact CD1-CE 4.25Å; F179-M255 HydrophobicContact CD1-CG 4.35Å; F179-M255 HydrophobicContact CE1-CE 3.67Å; F179-M255 HydrophobicContact CZ-CE 4.25Å; L235-M255 HydrophobicContact CD1-SD 4.36Å; L235-M255 HydrophobicContact CD2-SD 4.1Å; I253-M255 HydrophobicContact CG2-CG 4.31Å; M255-F294 HydrophobicContact CE-CD2 3.93Å; M255-F294 HydrophobicContact CE-CE2 4.12Å; M255-F294 HydrophobicContact SD-CD2 4.2Å; M255-V300 HydrophobicContact SD-CG1 4.13Å; M255-V300 HydrophobicContact SD-CG2 4.02Å; M255-S302 PolarHBondContact N-O 2.94Å; M255-I303 CarbonylContact O-C 3.53Å; M255-I303 WeakPolarHBondContact O-CA 3.46Å; M255-E304 WeakPolarHBondContact O-CB 3.34Å; M255-E304 PolarHBondContact O-N 2.91Å
256D98.6Very high97.5Very high0 Ų038.9 Ų38.90%022%0.222CC..EExtended strand (participates in β ladder)trans-108.6116.2157.3169.423.1000107.6Q177 E178 M180 A258 E304 K405Q177-D256 PolarHBondContact N-O 2.98Å; Q177-D256 PolarHBondContact NE2-OD2 3.38Å; E178-D256 HydrophobicContact CB-CB 3.81Å; E178-D256 HydrophobicContact CG-CB 3.77Å; E178-D256 PolarHBondContact N-O 2.95Å; E178-D256 PolarHBondContact O-N 3.36Å; M180-D256 HydrophobicContact CE-CB 4.16Å; D256-A258 PolarHBondContact OD1-N 2.55Å; D256-E304 HydrophobicContact CB-CB 4.01Å; D256-E304 HydrophobicContact CB-CG 4.23Å; D256-K405 IonicContact OD2-NZ 2.95Å
257V98.5Very high97.5Very high0 Ų041 Ų410%022%0.216CC..  trans-82.1-37.6-178.4173.80000110.1M176 A259 F262 Y291 I303 E304 D305M176-V257 HydrophobicContact CG-CG1 4.15Å; M176-V257 HydrophobicContact CG-CG2 4.36Å; M176-V257 HydrophobicContact SD-CG2 4.26Å; V257-A259 VanDerWaalsContact C-N 3.35Å; V257-A259 HydrophobicContact CG1-CB 3.78Å; V257-F262 HydrophobicContact CG1-CE1 3.89Å; V257-F262 HydrophobicContact CG1-CZ 3.43Å; V257-F262 VanDerWaalsContact CG1-CZ 3.43Å; V257-F262 WeakPolarHBondContact O-CE1 3.15Å; V257-Y291 HydrophobicContact CG1-CE1 4.46Å; V257-Y291 WeakPolarHBondContact CG1-OH 3.34Å; V257-Y291 HydrophobicContact CG2-CE1 3.84Å; V257-I303 HydrophobicContact CG2-CG2 3.89Å; V257-E304 PolarHBondContact N-O 2.73Å; V257-D305 WeakPolarHBondContact CB-O 3.49Å
258A97.3Very high97.5Very high3 Ų339.5 Ų39.53%0.02521%0.21CC..  trans49.450.4-169.200000113Q177 D256 S260 E261Q177-A258 HydrophobicContact CB-CB 3.8Å; Q177-A258 HydrophobicContact CG-CB 4.38Å; D256-A258 PolarHBondContact OD1-N 2.55Å; A258-S260 PolarHBondContact O-N 3.01Å; A258-S260 VanDerWaalsContact O-N 3.08Å; A258-E261 HydrophobicContact CB-CG 4.26Å; A258-E261 WeakPolarHBondContact O-CB 3.39Å; A258-E261 PolarHBondContact O-N 3.09Å
259A98.1Very high97.5Very high0 Ų036.2 Ų36.20%019%0.189CC..G310 helixtrans-62.3-22.4-167.900000115.1V257 E261 F262 F263 Y268 D305V257-A259 VanDerWaalsContact C-N 3.35Å; V257-A259 HydrophobicContact CG1-CB 3.78Å; A259-E261 PolarHBondContact O-N 2.94Å; A259-F262 HydrophobicContact CB-CE1 4.38Å; A259-F262 HydrophobicContact CB-CE2 3.98Å; A259-F262 HydrophobicContact CB-CZ 3.8Å; A259-F262 CarbonylContact O-C 3.57Å; A259-F262 PolarHBondContact O-N 3.31Å; A259-F263 PolarHBondContact O-N 2.89Å; A259-Y268 HydrophobicContact CB-CD1 4.12Å; A259-Y268 HydrophobicContact CB-CE1 3.84Å; A259-D305 VanDerWaalsContact CB-O 3.25Å; A259-D305 WeakPolarHBondContact CB-O 3.39Å; A259-D305 PolarHBondContact N-O 2.95Å; A259-D305 VanDerWaalsContact N-O 3.12Å
260S97.3Very high97.5Very high18 Ų1830.8 Ų30.813%0.12616%0.159CC..G310 helixtrans-57.1-33172.6-81.40000113.2A258 F262 F263 D308 Q309A258-S260 PolarHBondContact O-N 3.01Å; A258-S260 VanDerWaalsContact O-N 3.08Å; S260-F262 PolarHBondContact O-N 2.97Å; S260-F263 PolarHBondContact O-N 2.85Å; S260-D308 WeakPolarHBondContact CA-OD1 3.26Å; S260-D308 WeakPolarHBondContact CB-OD1 3.39Å; S260-D308 WeakPolarHBondContact OG-CA 3.22Å; S260-D308 PolarHBondContact OG-OD1 3.32Å; S260-Q309 PolarHBondContact OG-N 2.83Å
261E95.7Very high97.4Very high57 Ų5728.8 Ų28.827%0.26615%0.152SC..G310 helixtrans-64-28.6-179.1-66.1-66.8107.300112.5S168 A258 A259 R264 F272S168-E261 PolarHBondContact OG-OE2 2.65Å; A258-E261 HydrophobicContact CB-CG 4.26Å; A258-E261 WeakPolarHBondContact O-CB 3.39Å; A258-E261 PolarHBondContact O-N 3.09Å; A259-E261 PolarHBondContact O-N 2.94Å; E261-R264 PolarHBondContact O-NH1 2.89Å; E261-R264 PolarHBondContact O-NH2 3.18Å; E261-F272 HydrophobicContact CB-CZ 4.46Å
262F96.9Very high97.3Very high1 Ų130.2 Ų30.20%0.00416%0.158CC..G310 helixtrans-118.914-178.659.9-103.4000114.2A175 V257 A259 S260 Y268 D269 L270 F272 L287A175-F262 HydrophobicContact CB-CD1 4.35Å; A175-F262 HydrophobicContact CB-CE1 4.45Å; V257-F262 HydrophobicContact CG1-CE1 3.89Å; V257-F262 HydrophobicContact CG1-CZ 3.43Å; V257-F262 VanDerWaalsContact CG1-CZ 3.43Å; V257-F262 WeakPolarHBondContact O-CE1 3.15Å; A259-F262 HydrophobicContact CB-CE1 4.38Å; A259-F262 HydrophobicContact CB-CE2 3.98Å; A259-F262 HydrophobicContact CB-CZ 3.8Å; A259-F262 CarbonylContact O-C 3.57Å; A259-F262 PolarHBondContact O-N 3.31Å; S260-F262 PolarHBondContact O-N 2.97Å; F262-Y268 AromaticContact CD2-CD1 3.91Å; F262-Y268 HydrophobicContact CD2-CD1 3.91Å; F262-Y268 HydrophobicContact CD2-CG 4.43Å; F262-Y268 AromaticContact CE2-CD1 3.75Å; F262-Y268 HydrophobicContact CE2-CD1 3.75Å; F262-Y268 HydrophobicContact CE2-CG 4.29Å; F262-Y268 WeakPolarHBondContact O-CA 3.39Å; F262-D269 VanDerWaalsContact CB-O 3.28Å; F262-D269 WeakPolarHBondContact CB-O 3.39Å; F262-D269 PolarHBondContact O-N 3.36Å; F262-L270 HydrophobicContact CD2-CD2 4.35Å; F262-L270 HydrophobicContact CE2-CD2 3.79Å; F262-L270 HydrophobicContact CZ-CD2 4.02Å; F262-F272 HydrophobicContact CB-CB 3.79Å; F262-F272 HydrophobicContact CB-CD1 3.54Å; F262-F272 HydrophobicContact CB-CE1 4.2Å; F262-F272 HydrophobicContact CB-CG 3.71Å; F262-F272 HydrophobicContact CD1-CD1 4.28Å; F262-F272 HydrophobicContact CD1-CE1 4.24Å; F262-F272 HydrophobicContact CG-CD1 4.3Å; F262-L287 HydrophobicContact CE2-CD2 4.27Å
263F97.6Very high97.1Very high55 Ų5532.3 Ų32.324%0.24117%0.166CC..EExtended strand (participates in β ladder)trans-73127169.2-175.1-114.7000110.4A259 S260 G266 K267 Y268 D308A259-F263 PolarHBondContact O-N 2.89Å; S260-F263 PolarHBondContact O-N 2.85Å; F263-G266 VanDerWaalsContact CZ-CA 3.42Å; F263-K267 CarbonylContact C-O 3.53Å; F263-K267 WeakPolarHBondContact CA-O 3.32Å; F263-K267 WeakPolarHBondContact CD2-O 3.33Å; F263-Y268 HydrophobicContact CB-CD1 4.34Å; F263-Y268 HydrophobicContact CB-CE1 4.18Å; F263-Y268 AromaticContact CD2-CD1 3.98Å; F263-Y268 HydrophobicContact CD2-CD1 3.98Å; F263-Y268 HydrophobicContact CD2-CD2 4.43Å; F263-Y268 AromaticContact CD2-CE1 3.54Å; F263-Y268 HydrophobicContact CD2-CE1 3.54Å; F263-Y268 HydrophobicContact CD2-CE2 4.02Å; F263-Y268 HydrophobicContact CD2-CG 4.41Å; F263-Y268 AromaticContact CD2-CZ 3.55Å; F263-Y268 HydrophobicContact CE2-CE1 4.36Å; F263-Y268 HydrophobicContact CE2-CE2 4.15Å; F263-Y268 AromaticContact CE2-CZ 3.91Å; F263-Y268 HydrophobicContact CG-CE1 4.29Å; F263-D308 HydrophobicContact CB-CB 3.9Å; F263-D308 HydrophobicContact CD1-CB 3.87Å; F263-D308 HydrophobicContact CD2-CB 3.84Å; F263-D308 HydrophobicContact CE1-CB 4.28Å; F263-D308 HydrophobicContact CE2-CB 4.24Å; F263-D308 HydrophobicContact CG-CB 3.61Å; F263-D308 HydrophobicContact CZ-CB 4.43Å
264R96.2Very high96.8Very high78 Ų7833.2 Ų33.229%0.29417%0.172SC..EExtended strand (participates in β ladder)trans-138.4114.6-176.9-60.3-64.3178.5-89.6-4.3109.1E261 G266 K267 D269E261-R264 PolarHBondContact O-NH1 2.89Å; E261-R264 PolarHBondContact O-NH2 3.18Å; R264-G266 VanDerWaalsContact C-N 3.31Å; R264-G266 PolarHBondContact O-N 3.02Å; R264-G266 VanDerWaalsContact O-N 3.16Å; R264-K267 PolarHBondContact N-O 2.99Å; R264-K267 CarbonylContact O-C 3.55Å; R264-K267 WeakPolarHBondContact O-CA 3.1Å; R264-K267 PolarHBondContact O-N 3.23Å; R264-D269 HydrophobicContact CG-CB 4.2Å
265N92.8Very high96.6Very high156 Ų15638.8 Ų38.883%0.83421%0.209SC*.THydrogen-bonded Turntrans49.843.9170.9-56.1-43.2000114.6K267N265-K267 VanDerWaalsContact C-N 3.33Å
266G95.8Very high96.3Very high48 Ų4843.4 Ų43.450%0.49523%0.233SC..THydrogen-bonded Turntrans83.35-179.200000115.2F263 R264F263-G266 VanDerWaalsContact CZ-CA 3.42Å; R264-G266 VanDerWaalsContact C-N 3.31Å; R264-G266 PolarHBondContact O-N 3.02Å; R264-G266 VanDerWaalsContact O-N 3.16Å
267K98.2Very high96.2Very high97 Ų9746.7 Ų46.742%0.42225%0.251SS..EExtended strand (participates in β ladder)trans-132.5178.9179-65.8-172176.4-173.30110.9F263 R264 N265 H281 I282F263-K267 CarbonylContact C-O 3.53Å; F263-K267 WeakPolarHBondContact CA-O 3.32Å; F263-K267 WeakPolarHBondContact CD2-O 3.33Å; R264-K267 PolarHBondContact N-O 2.99Å; R264-K267 CarbonylContact O-C 3.55Å; R264-K267 WeakPolarHBondContact O-CA 3.1Å; R264-K267 PolarHBondContact O-N 3.23Å; N265-K267 VanDerWaalsContact C-N 3.33Å; K267-H281 HydrophobicContact CB-CB 3.81Å; K267-H281 HydrophobicContact CD-CB 3.83Å; K267-I282 CarbonylContact C-O 3.48Å; K267-I282 WeakPolarHBondContact CA-O 3.46Å; K267-I282 WeakPolarHBondContact CB-O 3.33Å
268Y98.4Very high96Very high0 Ų050.6 Ų50.60%028%0.276CS..EExtended strand (participates in β ladder)trans-125.6133.3-175.2-62.8-88.6000111.3A259 F262 F263 H281 I282 L287 F307 D308 D311A259-Y268 HydrophobicContact CB-CD1 4.12Å; A259-Y268 HydrophobicContact CB-CE1 3.84Å; F262-Y268 AromaticContact CD2-CD1 3.91Å; F262-Y268 HydrophobicContact CD2-CD1 3.91Å; F262-Y268 HydrophobicContact CD2-CG 4.43Å; F262-Y268 AromaticContact CE2-CD1 3.75Å; F262-Y268 HydrophobicContact CE2-CD1 3.75Å; F262-Y268 HydrophobicContact CE2-CG 4.29Å; F262-Y268 WeakPolarHBondContact O-CA 3.39Å; F263-Y268 HydrophobicContact CB-CD1 4.34Å; F263-Y268 HydrophobicContact CB-CE1 4.18Å; F263-Y268 AromaticContact CD2-CD1 3.98Å; F263-Y268 HydrophobicContact CD2-CD1 3.98Å; F263-Y268 HydrophobicContact CD2-CD2 4.43Å; F263-Y268 AromaticContact CD2-CE1 3.54Å; F263-Y268 HydrophobicContact CD2-CE1 3.54Å; F263-Y268 HydrophobicContact CD2-CE2 4.02Å; F263-Y268 HydrophobicContact CD2-CG 4.41Å; F263-Y268 AromaticContact CD2-CZ 3.55Å; F263-Y268 HydrophobicContact CE2-CE1 4.36Å; F263-Y268 HydrophobicContact CE2-CE2 4.15Å; F263-Y268 AromaticContact CE2-CZ 3.91Å; F263-Y268 HydrophobicContact CG-CE1 4.29Å; Y268-H281 WeakPolarHBondContact O-CA 3.5Å; Y268-I282 PolarHBondContact N-O 2.81Å; Y268-I282 PolarHBondContact O-N 2.72Å; Y268-L287 HydrophobicContact CD1-CD2 3.65Å; Y268-L287 HydrophobicContact CD2-CD2 3.72Å; Y268-L287 HydrophobicContact CE1-CD2 4.08Å; Y268-L287 HydrophobicContact CE2-CD2 4.17Å; Y268-L287 HydrophobicContact CG-CD2 3.44Å; Y268-L287 VanDerWaalsContact CG-CD2 3.44Å; Y268-F307 HydrophobicContact CE2-CD1 4.19Å; Y268-F307 AromaticContact CZ-CD1 3.97Å; Y268-F307 WeakPolarHBondContact OH-CB 3.27Å; Y268-D308 HydrophobicContact CE1-CB 4.3Å; Y268-D308 PolarHBondContact OH-N 3.33Å; Y268-D311 WeakPolarHBondContact OH-CB 3.38Å; Y268-D311 PolarHBondContact OH-OD2 3.44Å
269D97.8Very high95.9Very high2 Ų255.3 Ų55.31%0.01131%0.309CS..  trans-107.697.4-179.5-174.93.9000112.3F262 R264 D271 F272 R280 H281F262-D269 VanDerWaalsContact CB-O 3.28Å; F262-D269 WeakPolarHBondContact CB-O 3.39Å; F262-D269 PolarHBondContact O-N 3.36Å; R264-D269 HydrophobicContact CG-CB 4.2Å; D269-D271 PolarHBondContact O-N 3.35Å; D269-D271 PolarHBondContact OD1-N 2.99Å; D269-F272 HydrophobicContact CB-CB 4.14Å; D269-F272 WeakPolarHBondContact O-CB 3.35Å; D269-F272 PolarHBondContact O-N 3.48Å; D269-F272 PolarHBondContact OD1-N 2.98Å; D269-F272 WeakPolarHBondContact OD2-CA 3.33Å; D269-R280 IonicContact OD1-CZ 3.52Å; D269-R280 IonicContact OD1-NE 2.8Å; D269-R280 PolarHBondContact OD1-NE 3.03Å; D269-R280 IonicContact OD1-NH2 3.36Å; D269-R280 PolarHBondContact OD1-NH2 3.16Å; D269-R280 IonicContact OD2-CZ 3.66Å; D269-R280 IonicContact OD2-NE 3.7Å; D269-R280 PolarHBondContact OD2-NE 2.91Å; D269-R280 IonicContact OD2-NH2 2.75Å; D269-R280 PolarHBondContact OD2-NH2 3.14Å; D269-H281 IonicContact OD2-CD2 3.35Å; D269-H281 IonicContact OD2-NE2 2.87Å
270L97.3Very high95.8Very high37 Ų3758.5 Ų58.519%0.19432%0.321CS..THydrogen-bonded Turntrans-72.75.3179.9-60.7-178.5000114.7A175 M176 F262 I282 L287 L290A175-L270 HydrophobicContact CB-CB 4.37Å; A175-L270 HydrophobicContact CB-CD2 4.34Å; A175-L270 WeakPolarHBondContact CB-O 3.37Å; M176-L270 HydrophobicContact CE-CD2 4.41Å; F262-L270 HydrophobicContact CD2-CD2 4.35Å; F262-L270 HydrophobicContact CE2-CD2 3.79Å; F262-L270 HydrophobicContact CZ-CD2 4.02Å; L270-I282 HydrophobicContact CD1-CD1 3.65Å; L270-I282 HydrophobicContact CG-CD1 4.06Å; L270-L287 HydrophobicContact CD2-CD1 4.12Å; L270-L290 HydrophobicContact CD1-CD2 3.62Å
271D96.1Very high95.8Very high23 Ų2358.3 Ų58.312%0.12332%0.318CS..THydrogen-bonded Turntrans-132.834.1171.5-174.730.1000110.9L229 D269 K273 S274 R280L229-D271 HydrophobicContact CD1-CB 3.87Å; L229-D271 WeakPolarHBondContact CD1-OD1 3.23Å; D269-D271 PolarHBondContact O-N 3.35Å; D269-D271 PolarHBondContact OD1-N 2.99Å; D271-K273 PolarHBondContact O-N 2.81Å; D271-S274 VanDerWaalsContact CG-CB 3.47Å; D271-S274 WeakPolarHBondContact O-CB 3.38Å; D271-S274 PolarHBondContact O-N 2.96Å; D271-S274 VanDerWaalsContact OD1-CB 3.3Å; D271-S274 WeakPolarHBondContact OD1-CB 3.34Å; D271-S274 PolarHBondContact OD1-OG 2.94Å; D271-S274 VanDerWaalsContact OD2-CB 3.25Å; D271-S274 WeakPolarHBondContact OD2-CB 3.11Å; D271-S274 PolarHBondContact OD2-OG 3.5Å; D271-S274 VanDerWaalsContact OD2-OG 3.12Å; D271-R280 VanDerWaalsContact O-CZ 3.32Å; D271-R280 PolarHBondContact O-NH2 3.36Å; D271-R280 IonicContact OD2-CZ 3.97Å; D271-R280 IonicContact OD2-NH1 3.63Å; D271-R280 PolarHBondContact OD2-NH1 3.01Å
272F95.6Very high95.9Very high35 Ų3557.3 Ų57.315%0.15431%0.314CS..THydrogen-bonded Turntrans-57.3-15-17580-82.9000116.1A175 E261 F262 D269A175-F272 HydrophobicContact CB-CD1 4.02Å; A175-F272 HydrophobicContact CB-CE1 4.11Å; E261-F272 HydrophobicContact CB-CZ 4.46Å; F262-F272 HydrophobicContact CB-CB 3.79Å; F262-F272 HydrophobicContact CB-CD1 3.54Å; F262-F272 HydrophobicContact CB-CE1 4.2Å; F262-F272 HydrophobicContact CB-CG 3.71Å; F262-F272 HydrophobicContact CD1-CD1 4.28Å; F262-F272 HydrophobicContact CD1-CE1 4.24Å; F262-F272 HydrophobicContact CG-CD1 4.3Å; D269-F272 HydrophobicContact CB-CB 4.14Å; D269-F272 WeakPolarHBondContact O-CB 3.35Å; D269-F272 PolarHBondContact O-N 3.48Å; D269-F272 PolarHBondContact OD1-N 2.98Å; D269-F272 WeakPolarHBondContact OD2-CA 3.33Å
273K93.8Very high96Very high68 Ų6858.9 Ų58.930%0.29633%0.326SS..THydrogen-bonded Turntrans-85-14.5175.9-69.9-175.5-78.5-173.80113G167 A170 N172 K173 L174 D271G167-K273 WeakPolarHBondContact O-CD 3.49Å; G167-K273 PolarHBondContact O-NZ 3.46Å; A170-K273 PolarHBondContact O-NZ 3.23Å; N172-K273 VanDerWaalsContact O-CD 3.3Å; N172-K273 WeakPolarHBondContact O-CD 3.46Å; N172-K273 WeakPolarHBondContact O-CE 3.21Å; N172-K273 PolarHBondContact O-NZ 3.06Å; N172-K273 PolarHBondContact OD1-NZ 3.08Å; K173-K273 WeakPolarHBondContact O-CE 3.45Å; L174-K273 WeakPolarHBondContact O-CE 3.5Å; L174-K273 PolarHBondContact O-NZ 3.38Å; D271-K273 PolarHBondContact O-N 2.81Å
274S93.5Very high96Very high19 Ų1956.4 Ų56.413%0.13332%0.316CS..SBendtrans-87.9163.4166.7-62.40000109.8K173 D271 D276K173-S274 PolarHBondContact NZ-OG 3.39Å; D271-S274 VanDerWaalsContact CG-CB 3.47Å; D271-S274 WeakPolarHBondContact O-CB 3.38Å; D271-S274 PolarHBondContact O-N 2.96Å; D271-S274 VanDerWaalsContact OD1-CB 3.3Å; D271-S274 WeakPolarHBondContact OD1-CB 3.34Å; D271-S274 PolarHBondContact OD1-OG 2.94Å; D271-S274 VanDerWaalsContact OD2-CB 3.25Å; D271-S274 WeakPolarHBondContact OD2-CB 3.11Å; D271-S274 PolarHBondContact OD2-OG 3.5Å; D271-S274 VanDerWaalsContact OD2-OG 3.12Å; S274-D276 PolarHBondContact O-N 2.85Å
275P94.4Very high96.1Very high118 Ų11858.9 Ų58.977%0.76633%0.331SS*.SBendtrans-47.8137.9173.1-28.235.9000111.8R280P275-R280 PolarHBondContact O-NH1 2.77Å; P275-R280 PolarHBondContact O-NH2 3.34Å
276D93.1Very high96.4Very high96 Ų9656.5 Ų56.551%0.51331%0.314SS..PPolyproline II helixtrans-63.3134.6-173.8-174.333.3000111.6S274 H281S274-D276 PolarHBondContact O-N 2.85Å; D276-H281 IonicContact OD1-CE1 3.43Å; D276-H281 PolarHBondContact OD1-CE1 3.41Å; D276-H281 IonicContact OD1-NE2 3.82Å; D276-H281 PolarHBondContact OD1-NE2 3.39Å
277D95.1Very high96.6Very high70 Ų7054.2 Ų54.237%0.37429%0.291SS..  trans-139.8101176.2179.6-4.6000109.3S279 R280 H281D277-S279 VanDerWaalsContact CG-OG 3.23Å; D277-S279 PolarHBondContact O-N 2.9Å; D277-S279 VanDerWaalsContact OD1-CB 3.28Å; D277-S279 WeakPolarHBondContact OD1-CB 3.26Å; D277-S279 PolarHBondContact OD1-N 3.36Å; D277-S279 PolarHBondContact OD1-OG 2.63Å; D277-S279 PolarHBondContact OD2-OG 3.31Å; D277-R280 HydrophobicContact CB-CG 4.08Å; D277-R280 WeakPolarHBondContact O-CG 3.46Å; D277-R280 PolarHBondContact O-N 2.84Å; D277-H281 PolarHBondContact O-CD2 3.11Å; D277-H281 VanDerWaalsContact O-CD2 3.26Å; D277-H281 PolarHBondContact O-NE2 3.47Å
278P95.1Very high96.6Very high82 Ų8249.7 Ų49.753%0.53227%0.272SS..THydrogen-bonded Turntrans-60.2-16.4-179.7-27.136000115.4R280 H281P278-R280 VanDerWaalsContact C-N 3.35Å; P278-H281 PolarHBondContact O-N 2.78Å
279S95.9Very high96.6Very high102 Ų10253.7 Ų53.771%0.71329%0.293SS*.THydrogen-bonded Turntrans-74.2-24179.875.60000113.3D277D277-S279 VanDerWaalsContact CG-OG 3.23Å; D277-S279 PolarHBondContact O-N 2.9Å; D277-S279 VanDerWaalsContact OD1-CB 3.28Å; D277-S279 WeakPolarHBondContact OD1-CB 3.26Å; D277-S279 PolarHBondContact OD1-N 3.36Å; D277-S279 PolarHBondContact OD1-OG 2.63Å; D277-S279 PolarHBondContact OD2-OG 3.31Å
280R95.4Very high96.6Very high67 Ų6755.9 Ų55.925%0.25331%0.305SS..SBendtrans-89.6-6.817563167.8-167.2-134.1-11.5113.8D269 D271 P275 D277 P278 I282D269-R280 IonicContact OD1-CZ 3.52Å; D269-R280 IonicContact OD1-NE 2.8Å; D269-R280 PolarHBondContact OD1-NE 3.03Å; D269-R280 IonicContact OD1-NH2 3.36Å; D269-R280 PolarHBondContact OD1-NH2 3.16Å; D269-R280 IonicContact OD2-CZ 3.66Å; D269-R280 IonicContact OD2-NE 3.7Å; D269-R280 PolarHBondContact OD2-NE 2.91Å; D269-R280 IonicContact OD2-NH2 2.75Å; D269-R280 PolarHBondContact OD2-NH2 3.14Å; D271-R280 VanDerWaalsContact O-CZ 3.32Å; D271-R280 PolarHBondContact O-NH2 3.36Å; D271-R280 IonicContact OD2-CZ 3.97Å; D271-R280 IonicContact OD2-NH1 3.63Å; D271-R280 PolarHBondContact OD2-NH1 3.01Å; P275-R280 PolarHBondContact O-NH1 2.77Å; P275-R280 PolarHBondContact O-NH2 3.34Å; D277-R280 HydrophobicContact CB-CG 4.08Å; D277-R280 WeakPolarHBondContact O-CG 3.46Å; D277-R280 PolarHBondContact O-N 2.84Å; P278-R280 VanDerWaalsContact C-N 3.35Å; R280-I282 PolarHBondContact O-N 2.71Å
281H97.6Very high96.7Very high13 Ų1354.1 Ų54.16%0.0630%0.295CS..  trans-67.6130.2-179.9-63.4179.2000110.8K267 Y268 D269 D276 D277 P278K267-H281 HydrophobicContact CB-CB 3.81Å; K267-H281 HydrophobicContact CD-CB 3.83Å; Y268-H281 WeakPolarHBondContact O-CA 3.5Å; D269-H281 IonicContact OD2-CD2 3.35Å; D269-H281 IonicContact OD2-NE2 2.87Å; D276-H281 IonicContact OD1-CE1 3.43Å; D276-H281 PolarHBondContact OD1-CE1 3.41Å; D276-H281 IonicContact OD1-NE2 3.82Å; D276-H281 PolarHBondContact OD1-NE2 3.39Å; D277-H281 PolarHBondContact O-CD2 3.11Å; D277-H281 VanDerWaalsContact O-CD2 3.26Å; D277-H281 PolarHBondContact O-NE2 3.47Å; P278-H281 PolarHBondContact O-N 2.78Å
282I98.3Very high96.8Very high36 Ų3657 Ų5719%0.18530%0.304CS..BIsolated β-bridgetrans-104.2151.6-179.263.4172.6000111.2K267 Y268 L270 R280 Q286 L287K267-I282 CarbonylContact C-O 3.48Å; K267-I282 WeakPolarHBondContact CA-O 3.46Å; K267-I282 WeakPolarHBondContact CB-O 3.33Å; Y268-I282 PolarHBondContact N-O 2.81Å; Y268-I282 PolarHBondContact O-N 2.72Å; L270-I282 HydrophobicContact CD1-CD1 3.65Å; L270-I282 HydrophobicContact CG-CD1 4.06Å; R280-I282 PolarHBondContact O-N 2.71Å; I282-Q286 HydrophobicContact CB-CB 4.02Å; I282-L287 HydrophobicContact CD1-CB 3.95Å; I282-L287 HydrophobicContact CD1-CD1 4.01Å; I282-L287 HydrophobicContact CG1-CB 4.45Å
283S98.4Very high97Very high35 Ų3558 Ų5825%0.24532%0.316CS..  trans-71.9161.9174.874.40000111.4E285 Q286 L287S283-E285 PolarHBondContact O-N 2.93Å; S283-E285 PolarHBondContact OG-N 2.98Å; S283-Q286 PolarHBondContact O-N 2.93Å; S283-Q286 WeakPolarHBondContact OG-CG 3.46Å; S283-Q286 PolarHBondContact OG-N 2.92Å; S283-L287 WeakPolarHBondContact O-CB 3.39Å; S283-L287 PolarHBondContact O-N 2.78Å
284G98.4Very high97.2Very high3 Ų355 Ų553%0.03130%0.303CS..Hα-helixtrans-60.5-26.9171.700000113.4G288 F307 Q314G284-G288 PolarHBondContact O-N 2.9Å; G284-F307 VanDerWaalsContact O-CE1 3.27Å; G284-F307 WeakPolarHBondContact O-CE1 3.44Å; G284-Q314 VanDerWaalsContact C-NE2 3.27Å; G284-Q314 VanDerWaalsContact CA-NE2 3.31Å
285E98.3Very high97.4Very high130 Ų13056 Ų5661%0.60731%0.306SS*.Hα-helixtrans-68.5-47.1174.5-176.8175.7-162.700111.2S283 L287 G288 D289 Q314S283-E285 PolarHBondContact O-N 2.93Å; S283-E285 PolarHBondContact OG-N 2.98Å; E285-L287 VanDerWaalsContact C-N 3.29Å; E285-L287 PolarHBondContact O-N 2.81Å; E285-G288 PolarHBondContact O-N 2.77Å; E285-D289 PolarHBondContact O-N 2.66Å; E285-Q314 VanDerWaalsContact N-NE2 3.16Å
286Q98.6Very high97.6Very high106 Ų10659.6 Ų59.650%0.49531%0.31SS..Hα-helixtrans-62-38175.6-69.8174.2-55.700111.7I282 S283 D289 L290I282-Q286 HydrophobicContact CB-CB 4.02Å; S283-Q286 PolarHBondContact O-N 2.93Å; S283-Q286 WeakPolarHBondContact OG-CG 3.46Å; S283-Q286 PolarHBondContact OG-N 2.92Å; Q286-D289 PolarHBondContact O-N 3.5Å; Q286-L290 PolarHBondContact O-N 2.98Å
287L98.7Very high97.8Very high0 Ų057.1 Ų57.10%031%0.308CS..Hα-helixtrans-67-41.4175.2-176.458.6000111.6F262 Y268 L270 I282 S283 E285 D289 L290 Y291 F307F262-L287 HydrophobicContact CE2-CD2 4.27Å; Y268-L287 HydrophobicContact CD1-CD2 3.65Å; Y268-L287 HydrophobicContact CD2-CD2 3.72Å; Y268-L287 HydrophobicContact CE1-CD2 4.08Å; Y268-L287 HydrophobicContact CE2-CD2 4.17Å; Y268-L287 HydrophobicContact CG-CD2 3.44Å; Y268-L287 VanDerWaalsContact CG-CD2 3.44Å; L270-L287 HydrophobicContact CD2-CD1 4.12Å; I282-L287 HydrophobicContact CD1-CB 3.95Å; I282-L287 HydrophobicContact CD1-CD1 4.01Å; I282-L287 HydrophobicContact CG1-CB 4.45Å; S283-L287 WeakPolarHBondContact O-CB 3.39Å; S283-L287 PolarHBondContact O-N 2.78Å; E285-L287 VanDerWaalsContact C-N 3.29Å; E285-L287 PolarHBondContact O-N 2.81Å; L287-D289 VanDerWaalsContact C-N 3.33Å; L287-D289 PolarHBondContact O-N 2.9Å; L287-L290 HydrophobicContact CD1-CD2 4.31Å; L287-L290 WeakPolarHBondContact O-CB 3.22Å; L287-L290 PolarHBondContact O-N 3.45Å; L287-Y291 HydrophobicContact CD1-CE1 3.85Å; L287-Y291 HydrophobicContact CD1-CE2 4.13Å; L287-Y291 VanDerWaalsContact CD1-CZ 3.5Å; L287-Y291 VanDerWaalsContact CD1-OH 3.28Å; L287-Y291 WeakPolarHBondContact CD1-OH 3.49Å; L287-Y291 HydrophobicContact CD2-CE2 4.25Å; L287-Y291 VanDerWaalsContact CD2-OH 3.27Å; L287-Y291 WeakPolarHBondContact CD2-OH 3.32Å; L287-Y291 HydrophobicContact CG-CE1 4.27Å; L287-Y291 HydrophobicContact CG-CE2 3.61Å; L287-Y291 VanDerWaalsContact CG-CZ 3.45Å; L287-Y291 VanDerWaalsContact CG-OH 3.22Å; L287-Y291 WeakPolarHBondContact CG-OH 3.39Å; L287-Y291 VanDerWaalsContact O-CD2 3.3Å; L287-Y291 WeakPolarHBondContact O-CD2 3.46Å; L287-Y291 PolarHBondContact O-N 3.06Å; L287-F307 HydrophobicContact CB-CE1 4.32Å; L287-F307 HydrophobicContact CD2-CD1 4.23Å; L287-F307 HydrophobicContact CD2-CE1 4.27Å; L287-F307 HydrophobicContact CG-CE1 4.31Å
288G98.6Very high97.9Very high2 Ų254.8 Ų54.82%0.02129%0.293CS..Hα-helixtrans-60.4-39171.700000113.5G284 E285 L290 Y291 R292G284-G288 PolarHBondContact O-N 2.9Å; E285-G288 PolarHBondContact O-N 2.77Å; G288-L290 VanDerWaalsContact C-N 3.35Å; G288-Y291 PolarHBondContact O-N 2.84Å; G288-R292 PolarHBondContact O-N 3.4Å
289D98.6Very high98Very high83 Ų8353.4 Ų53.444%0.44428%0.284SS..Hα-helixtrans-63.9-39.7173.2-79.5-32000112.2E285 Q286 L287 Y291 R292 S293E285-D289 PolarHBondContact O-N 2.66Å; Q286-D289 PolarHBondContact O-N 3.5Å; L287-D289 VanDerWaalsContact C-N 3.33Å; L287-D289 PolarHBondContact O-N 2.9Å; D289-Y291 PolarHBondContact O-N 3.02Å; D289-R292 PolarHBondContact O-N 2.61Å; D289-R292 IonicContact OD1-CZ 3.46Å; D289-R292 VanDerWaalsContact OD1-CZ 3.31Å; D289-R292 IonicContact OD1-NE 2.89Å; D289-R292 PolarHBondContact OD1-NE 3.3Å; D289-R292 VanDerWaalsContact OD1-NE 3.15Å; D289-R292 IonicContact OD1-NH2 3.65Å; D289-R292 PolarHBondContact OD1-NH2 3.35Å; D289-S293 PolarHBondContact O-N 3.06Å
290L98.6Very high98.2Very high49 Ų4948.5 Ų48.526%0.25725%0.25SS..Hα-helixtrans-59.7-46.9174.5-176.164.6000110.9M176 L270 Q286 L287 G288 R292 S293 F294M176-L290 HydrophobicContact CE-CD2 4.24Å; L270-L290 HydrophobicContact CD1-CD2 3.62Å; Q286-L290 PolarHBondContact O-N 2.98Å; L287-L290 HydrophobicContact CD1-CD2 4.31Å; L287-L290 WeakPolarHBondContact O-CB 3.22Å; L287-L290 PolarHBondContact O-N 3.45Å; G288-L290 VanDerWaalsContact C-N 3.35Å; L290-R292 PolarHBondContact O-N 3.39Å; L290-S293 WeakPolarHBondContact O-CB 3.49Å; L290-S293 PolarHBondContact O-N 2.76Å; L290-S293 VanDerWaalsContact O-N 3.1Å; L290-S293 PolarHBondContact O-OG 2.53Å; L290-F294 HydrophobicContact CD1-CE1 3.73Å; L290-F294 HydrophobicContact CD1-CE2 4.46Å; L290-F294 HydrophobicContact CD1-CZ 3.63Å; L290-F294 HydrophobicContact CD2-CE2 4.29Å; L290-F294 HydrophobicContact CD2-CZ 3.99Å; L290-F294 HydrophobicContact CG-CE1 4.09Å; L290-F294 HydrophobicContact CG-CE2 3.93Å; L290-F294 HydrophobicContact CG-CZ 3.57Å; L290-F294 PolarHBondContact O-N 2.91Å; L290-F294 VanDerWaalsContact O-N 3.08Å
291Y98.8Very high98.3Very high0 Ų048.8 Ų48.80%026%0.255CS..Hα-helixtrans-62.5-41.6176.4-56.7-39.5000113M176 V257 L287 G288 D289 S293 F294 I295 I303 P306 F307 F318M176-Y291 HydrophobicContact CE-CD1 4.31Å; M176-Y291 HydrophobicContact CE-CE1 3.57Å; M176-Y291 HydrophobicContact SD-CE1 4.45Å; V257-Y291 HydrophobicContact CG1-CE1 4.46Å; V257-Y291 WeakPolarHBondContact CG1-OH 3.34Å; V257-Y291 HydrophobicContact CG2-CE1 3.84Å; L287-Y291 HydrophobicContact CD1-CE1 3.85Å; L287-Y291 HydrophobicContact CD1-CE2 4.13Å; L287-Y291 VanDerWaalsContact CD1-CZ 3.5Å; L287-Y291 VanDerWaalsContact CD1-OH 3.28Å; L287-Y291 WeakPolarHBondContact CD1-OH 3.49Å; L287-Y291 HydrophobicContact CD2-CE2 4.25Å; L287-Y291 VanDerWaalsContact CD2-OH 3.27Å; L287-Y291 WeakPolarHBondContact CD2-OH 3.32Å; L287-Y291 HydrophobicContact CG-CE1 4.27Å; L287-Y291 HydrophobicContact CG-CE2 3.61Å; L287-Y291 VanDerWaalsContact CG-CZ 3.45Å; L287-Y291 VanDerWaalsContact CG-OH 3.22Å; L287-Y291 WeakPolarHBondContact CG-OH 3.39Å; L287-Y291 VanDerWaalsContact O-CD2 3.3Å; L287-Y291 WeakPolarHBondContact O-CD2 3.46Å; L287-Y291 PolarHBondContact O-N 3.06Å; G288-Y291 PolarHBondContact O-N 2.84Å; D289-Y291 PolarHBondContact O-N 3.02Å; Y291-S293 PolarHBondContact O-N 3.22Å; Y291-F294 HydrophobicContact CD1-CD2 4.34Å; Y291-F294 WeakPolarHBondContact O-CB 3.12Å; Y291-F294 PolarHBondContact O-N 3.04Å; Y291-I295 WeakPolarHBondContact O-CG1 3.43Å; Y291-I295 PolarHBondContact O-N 2.88Å; Y291-I303 HydrophobicContact CG-CD1 4.33Å; Y291-P306 HydrophobicContact CD2-CB 4.01Å; Y291-P306 HydrophobicContact CE2-CB 3.45Å; Y291-P306 VanDerWaalsContact CE2-CB 3.45Å; Y291-P306 VanDerWaalsContact CE2-O 3.26Å; Y291-P306 WeakPolarHBondContact CE2-O 3.46Å; Y291-P306 PolarHBondContact OH-O 2.84Å; Y291-F307 HydrophobicContact CD2-CZ 4.28Å; Y291-F307 HydrophobicContact CE2-CE1 4.15Å; Y291-F307 HydrophobicContact CE2-CZ 4.01Å; Y291-F318 VanDerWaalsContact CB-CZ 3.42Å; Y291-F318 HydrophobicContact CD2-CE1 4.11Å; Y291-F318 HydrophobicContact CD2-CE2 4.05Å; Y291-F318 AromaticContact CD2-CZ 3.83Å; Y291-F318 HydrophobicContact CD2-CZ 3.83Å; Y291-F318 HydrophobicContact CG-CE2 4.38Å; Y291-F318 HydrophobicContact CG-CZ 4.04Å
292R98.6Very high98.4Very high82 Ų8248.3 Ų48.331%0.30925%0.253SS..Hα-helixtrans-58.6-37.2173.9-77-176-77.7-86.21.7111.5G288 D289 L290 F294 I295 K296 F318 S321 V322G288-R292 PolarHBondContact O-N 3.4Å; D289-R292 PolarHBondContact O-N 2.61Å; D289-R292 IonicContact OD1-CZ 3.46Å; D289-R292 VanDerWaalsContact OD1-CZ 3.31Å; D289-R292 IonicContact OD1-NE 2.89Å; D289-R292 PolarHBondContact OD1-NE 3.3Å; D289-R292 VanDerWaalsContact OD1-NE 3.15Å; D289-R292 IonicContact OD1-NH2 3.65Å; D289-R292 PolarHBondContact OD1-NH2 3.35Å; L290-R292 PolarHBondContact O-N 3.39Å; R292-F294 VanDerWaalsContact C-N 3.35Å; R292-I295 PolarHBondContact O-N 2.96Å; R292-K296 WeakPolarHBondContact O-CB 3.46Å; R292-K296 PolarHBondContact O-N 2.89Å; R292-F318 HydrophobicContact CG-CE2 4.21Å; R292-S321 PolarHBondContact NH1-OG 2.8Å; R292-V322 HydrophobicContact CG-CG1 4.37Å
293S98.4Very high98.4Very high58 Ų5846.6 Ų46.641%0.40624%0.244SC..Hα-helixtrans-64.4-38.8174.586.20000112.1D289 L290 Y291 K296 G297D289-S293 PolarHBondContact O-N 3.06Å; L290-S293 WeakPolarHBondContact O-CB 3.49Å; L290-S293 PolarHBondContact O-N 2.76Å; L290-S293 VanDerWaalsContact O-N 3.1Å; L290-S293 PolarHBondContact O-OG 2.53Å; Y291-S293 PolarHBondContact O-N 3.22Å; S293-K296 PolarHBondContact O-N 3.49Å; S293-G297 PolarHBondContact O-N 3.04Å
294F98.6Very high98.4Very high4 Ų445 Ų452%0.01823%0.232CC..Hα-helixtrans-67.1-44.6176-61.6-19.2000112.3M176 N231 N232 L235 M255 L290 Y291 R292 K296 G297 Y298M176-F294 HydrophobicContact CE-CE2 3.88Å; M176-F294 HydrophobicContact SD-CE2 4.08Å; N231-F294 HydrophobicContact CB-CE2 4.07Å; N231-F294 HydrophobicContact CB-CZ 3.86Å; N232-F294 HydrophobicContact CB-CE1 4.09Å; L235-F294 HydrophobicContact CD1-CB 3.79Å; L235-F294 HydrophobicContact CD1-CD1 3.75Å; L235-F294 HydrophobicContact CD1-CD2 3.9Å; L235-F294 HydrophobicContact CD1-CE1 4.29Å; L235-F294 HydrophobicContact CD1-CE2 4.41Å; L235-F294 HydrophobicContact CD1-CG 3.55Å; M255-F294 HydrophobicContact CE-CD2 3.93Å; M255-F294 HydrophobicContact CE-CE2 4.12Å; M255-F294 HydrophobicContact SD-CD2 4.2Å; L290-F294 HydrophobicContact CD1-CE1 3.73Å; L290-F294 HydrophobicContact CD1-CE2 4.46Å; L290-F294 HydrophobicContact CD1-CZ 3.63Å; L290-F294 HydrophobicContact CD2-CE2 4.29Å; L290-F294 HydrophobicContact CD2-CZ 3.99Å; L290-F294 HydrophobicContact CG-CE1 4.09Å; L290-F294 HydrophobicContact CG-CE2 3.93Å; L290-F294 HydrophobicContact CG-CZ 3.57Å; L290-F294 PolarHBondContact O-N 2.91Å; L290-F294 VanDerWaalsContact O-N 3.08Å; Y291-F294 HydrophobicContact CD1-CD2 4.34Å; Y291-F294 WeakPolarHBondContact O-CB 3.12Å; Y291-F294 PolarHBondContact O-N 3.04Å; R292-F294 VanDerWaalsContact C-N 3.35Å; F294-K296 PolarHBondContact O-N 3.04Å; F294-G297 PolarHBondContact O-N 3.06Å; F294-Y298 HydrophobicContact CB-CD2 4.48Å; F294-Y298 WeakPolarHBondContact O-CB 3.42Å; F294-Y298 WeakPolarHBondContact O-CD2 3.41Å; F294-Y298 PolarHBondContact O-N 3.23Å
295I98.5Very high98.5Very high40 Ų4044.9 Ų44.921%0.20523%0.231CC..Hα-helixtrans-60.5-34.7176.4-63.3163.5000111Y291 R292 V300 I303 F318 V322 I324Y291-I295 WeakPolarHBondContact O-CG1 3.43Å; Y291-I295 PolarHBondContact O-N 2.88Å; R292-I295 PolarHBondContact O-N 2.96Å; I295-V300 HydrophobicContact CG1-CB 4.43Å; I295-V300 HydrophobicContact CG1-CG1 4.3Å; I295-I303 HydrophobicContact CD1-CD1 4.14Å; I295-I303 HydrophobicContact CG1-CD1 4.27Å; I295-F318 HydrophobicContact CD1-CZ 4.12Å; I295-V322 HydrophobicContact CD1-CB 4.37Å; I295-V322 HydrophobicContact CD1-CG1 3.86Å; I295-I324 HydrophobicContact CD1-CD1 3.56Å; I295-I324 HydrophobicContact CD1-CG1 4.07Å; I295-I324 HydrophobicContact CG1-CD1 3.96Å; I295-I324 HydrophobicContact CG2-CG2 4.1Å
296K97.8Very high98.5Very high193 Ų19338.7 Ų38.784%0.83920%0.202SC*.Hα-helixtrans-75.4-36.8176.8-174.7179.3177.2-177.20112.9R292 S293 F294R292-K296 WeakPolarHBondContact O-CB 3.46Å; R292-K296 PolarHBondContact O-N 2.89Å; S293-K296 PolarHBondContact O-N 3.49Å; F294-K296 PolarHBondContact O-N 3.04Å
297G97.4Very high98.5Very high45 Ų4533.8 Ų33.846%0.46418%0.179SC..Hα-helixtrans-86.9-25.2-174.200000114.9S293 F294S293-G297 PolarHBondContact O-N 3.04Å; F294-G297 PolarHBondContact O-N 3.06Å
298Y98.1Very high98.5Very high20 Ų2034.5 Ų34.58%0.07818%0.183CC..SBendtrans-137.2159.8-169.7-55.8-78.8000111N232 L235 E236 K239 F294 V300N232-Y298 PolarHBondContact ND2-OH 2.92Å; N232-Y298 WeakPolarHBondContact OD1-CE2 3.33Å; N232-Y298 PolarHBondContact OD1-OH 3.07Å; L235-Y298 HydrophobicContact CB-CD1 3.8Å; L235-Y298 HydrophobicContact CB-CD2 3.89Å; L235-Y298 HydrophobicContact CB-CE1 3.84Å; L235-Y298 HydrophobicContact CB-CE2 3.93Å; L235-Y298 HydrophobicContact CB-CG 3.84Å; L235-Y298 HydrophobicContact CD1-CD2 3.54Å; L235-Y298 HydrophobicContact CD1-CE2 3.89Å; L235-Y298 HydrophobicContact CD1-CG 4.11Å; L235-Y298 HydrophobicContact CG-CD2 4.27Å; L235-Y298 HydrophobicContact CG-CG 4.43Å; E236-Y298 VanDerWaalsContact CD-CE1 3.44Å; E236-Y298 HydrophobicContact CG-CE1 4.04Å; E236-Y298 WeakPolarHBondContact CG-OH 3.33Å; E236-Y298 VanDerWaalsContact OE1-CE1 3.26Å; E236-Y298 WeakPolarHBondContact OE1-CE1 3.37Å; E236-Y298 VanDerWaalsContact OE1-CZ 3.3Å; E236-Y298 PolarHBondContact OE1-OH 3.43Å; K239-Y298 HydrophobicContact CD-CD1 4.38Å; K239-Y298 HydrophobicContact CD-CE1 4.38Å; F294-Y298 HydrophobicContact CB-CD2 4.48Å; F294-Y298 WeakPolarHBondContact O-CB 3.42Å; F294-Y298 WeakPolarHBondContact O-CD2 3.41Å; F294-Y298 PolarHBondContact O-N 3.23Å; Y298-V300 PolarHBondContact O-N 3.28Å
299P97.4Very high98.4Very high53 Ų5335.4 Ų35.434%0.34419%0.187SC..  trans-754417734-37.7000112.4I252 I253 Q301I252-P299 WeakPolarHBondContact CA-O 3.35Å; I253-P299 HydrophobicContact CD1-CG 4.17Å; I253-P299 HydrophobicContact CG1-CG 4.24Å; I253-P299 PolarHBondContact N-O 3.12Å; P299-Q301 PolarHBondContact O-N 2.78Å
300V98.7Very high98.3Very high0 Ų035.1 Ų35.10%019%0.185CC..EExtended strand (participates in β ladder)trans-72.1123.1175.5176.30000108.7L235 I253 M255 I295 Y298 I303L235-V300 HydrophobicContact CD2-CG2 4.03Å; I253-V300 HydrophobicContact CB-CG2 4.09Å; I253-V300 HydrophobicContact CG2-CG2 3.95Å; I253-V300 WeakPolarHBondContact O-CA 3.44Å; M255-V300 HydrophobicContact SD-CG1 4.13Å; M255-V300 HydrophobicContact SD-CG2 4.02Å; I295-V300 HydrophobicContact CG1-CB 4.43Å; I295-V300 HydrophobicContact CG1-CG1 4.3Å; Y298-V300 PolarHBondContact O-N 3.28Å; V300-I303 HydrophobicContact CG1-CD1 4Å; V300-I303 HydrophobicContact CG1-CG1 3.73Å
301Q98.7Very high98.3Very high73 Ų7334.2 Ų34.234%0.34118%0.181SC..EExtended strand (participates in β ladder)trans-134.2-1.5-174.5-68.7-62.1-57.400113I252 I253 P299 Q325I252-Q301 HydrophobicContact CB-CB 4.01Å; I252-Q301 HydrophobicContact CB-CG 3.88Å; I252-Q301 HydrophobicContact CD1-CB 3.65Å; I252-Q301 HydrophobicContact CD1-CG 4.27Å; I252-Q301 HydrophobicContact CG1-CB 4.24Å; I252-Q301 HydrophobicContact CG2-CB 4.37Å; I252-Q301 HydrophobicContact CG2-CG 3.82Å; I253-Q301 PolarHBondContact O-N 3.49Å; P299-Q301 PolarHBondContact O-N 2.78Å; Q301-Q325 WeakPolarHBondContact O-CB 3.48Å; Q301-Q325 PolarHBondContact O-N 3.25Å
302S98.9Very high98.3Very high2 Ų235.7 Ų35.71%0.01419%0.186CC..EExtended strand (participates in β ladder)trans-144.5129.1171.2-171.50000110.1G254 M255 Q325 V327G254-S302 CarbonylContact C-O 3.4Å; G254-S302 VanDerWaalsContact CA-O 3.28Å; G254-S302 WeakPolarHBondContact CA-O 3.42Å; M255-S302 PolarHBondContact N-O 2.94Å; S302-Q325 CarbonylContact C-O 3.58Å; S302-Q325 VanDerWaalsContact CA-O 3.26Å; S302-Q325 WeakPolarHBondContact CA-O 3.38Å; S302-Q325 PolarHBondContact OG-NE2 2.84Å; S302-V327 WeakPolarHBondContact OG-CG2 3.41Å
303I98.9Very high98.2Very high0 Ų037.6 Ų37.60%020%0.199CC..EExtended strand (participates in β ladder)trans-127.7123.5171.8-60.5178.4000108.6M255 V257 Y291 I295 V300 P306 F318 I324 Q325 I326 V327M255-I303 CarbonylContact O-C 3.53Å; M255-I303 WeakPolarHBondContact O-CA 3.46Å; V257-I303 HydrophobicContact CG2-CG2 3.89Å; Y291-I303 HydrophobicContact CG-CD1 4.33Å; I295-I303 HydrophobicContact CD1-CD1 4.14Å; I295-I303 HydrophobicContact CG1-CD1 4.27Å; V300-I303 HydrophobicContact CG1-CD1 4Å; V300-I303 HydrophobicContact CG1-CG1 3.73Å; I303-P306 HydrophobicContact CG2-CB 3.91Å; I303-P306 HydrophobicContact CG2-CG 4.42Å; I303-F318 HydrophobicContact CD1-CE1 4.39Å; I303-F318 HydrophobicContact CD1-CZ 4.21Å; I303-I324 HydrophobicContact CB-CD1 4.24Å; I303-I324 HydrophobicContact CD1-CD1 3.75Å; I303-I324 HydrophobicContact CG1-CD1 3.66Å; I303-Q325 PolarHBondContact N-O 3.42Å; I303-I326 HydrophobicContact CB-CD1 4.21Å; I303-I326 CarbonylContact O-C 3.52Å; I303-I326 VanDerWaalsContact O-CA 3.31Å; I303-I326 WeakPolarHBondContact O-CA 3.23Å; I303-V327 PolarHBondContact O-N 2.92Å
304E98.9Very high98.3Very high1 Ų136.2 Ų36.21%0.00519%0.186CC..EExtended strand (participates in β ladder)trans-101.9141.3176.1179.8-175.2144.300110.2M255 D256 V257 P306 V327 D329 L352 K405M255-E304 WeakPolarHBondContact O-CB 3.34Å; M255-E304 PolarHBondContact O-N 2.91Å; D256-E304 HydrophobicContact CB-CB 4.01Å; D256-E304 HydrophobicContact CB-CG 4.23Å; V257-E304 PolarHBondContact N-O 2.73Å; E304-P306 VanDerWaalsContact C-CD 3.43Å; E304-V327 WeakPolarHBondContact CA-O 3.36Å; E304-V327 HydrophobicContact CB-CB 3.76Å; E304-V327 HydrophobicContact CB-CG1 4.4Å; E304-V327 HydrophobicContact CB-CG2 4.33Å; E304-V327 HydrophobicContact CG-CB 3.95Å; E304-V327 HydrophobicContact CG-CG1 4.12Å; E304-D329 HydrophobicContact CG-CB 3.95Å; E304-D329 WeakPolarHBondContact OE1-CB 3.28Å; E304-L352 WeakPolarHBondContact OE1-CD2 3.3Å; E304-K405 IonicContact OE1-NZ 3.3Å; E304-K405 PolarHBondContact OE1-NZ 2.62Å; E304-K405 WeakPolarHBondContact OE2-CE 3.36Å; E304-K405 IonicContact OE2-NZ 3.39Å; E304-K405 PolarHBondContact OE2-NZ 3.34Å
305D98.6Very high98.3Very high1 Ų136 Ų361%0.00519%0.185CC..  trans42.452.4179.5-73.3-1.4000115.6V257 A259 F307 W315 V327 D329 D330V257-D305 WeakPolarHBondContact CB-O 3.49Å; A259-D305 VanDerWaalsContact CB-O 3.25Å; A259-D305 WeakPolarHBondContact CB-O 3.39Å; A259-D305 PolarHBondContact N-O 2.95Å; A259-D305 VanDerWaalsContact N-O 3.12Å; D305-F307 PolarHBondContact O-N 3.21Å; D305-F307 VanDerWaalsContact O-N 3.13Å; D305-W315 HydrophobicContact CB-CH2 4.42Å; D305-W315 HydrophobicContact CB-CZ2 4.35Å; D305-W315 VanDerWaalsContact OD1-CH2 3.23Å; D305-W315 WeakPolarHBondContact OD1-CH2 3.43Å; D305-W315 WeakPolarHBondContact OD1-CZ2 3.24Å; D305-V327 PolarHBondContact N-O 3.07Å; D305-V327 VanDerWaalsContact N-O 3.12Å; D305-D329 PolarHBondContact OD1-N 3.43Å; D305-D329 WeakPolarHBondContact OD2-CB 3.45Å; D305-D330 PolarHBondContact OD1-N 2.96Å; D305-D330 VanDerWaalsContact OD2-CB 3.29Å; D305-D330 WeakPolarHBondContact OD2-CB 3.5Å; D305-D330 PolarHBondContact OD2-N 2.67Å
306P98.8Very high98.3Very high0 Ų035.5 Ų35.50%019%0.186CC..  trans-61.4-21.5-179.725.4-35.7000114.1Y291 I303 E304 W315 F318 I326Y291-P306 HydrophobicContact CD2-CB 4.01Å; Y291-P306 HydrophobicContact CE2-CB 3.45Å; Y291-P306 VanDerWaalsContact CE2-CB 3.45Å; Y291-P306 VanDerWaalsContact CE2-O 3.26Å; Y291-P306 WeakPolarHBondContact CE2-O 3.46Å; Y291-P306 PolarHBondContact OH-O 2.84Å; I303-P306 HydrophobicContact CG2-CB 3.91Å; I303-P306 HydrophobicContact CG2-CG 4.42Å; E304-P306 VanDerWaalsContact C-CD 3.43Å; P306-W315 HydrophobicContact CG-CD2 4.44Å; P306-W315 HydrophobicContact CG-CE3 4.09Å; P306-W315 HydrophobicContact CG-CH2 4.32Å; P306-W315 HydrophobicContact CG-CZ3 4.04Å; P306-F318 HydrophobicContact CB-CD1 4.29Å; P306-F318 HydrophobicContact CB-CE1 4.32Å; P306-F318 HydrophobicContact CG-CD1 4.22Å; P306-I326 HydrophobicContact CG-CG2 4.21Å
307F98.8Very high98.3Very high3 Ų331.7 Ų31.71%0.01317%0.17CC..SBendtrans-138.6168.3-178.5-56-71.6000110.4Y268 G284 L287 Y291 D305 D311 Q314 W315 F318Y268-F307 HydrophobicContact CE2-CD1 4.19Å; Y268-F307 AromaticContact CZ-CD1 3.97Å; Y268-F307 WeakPolarHBondContact OH-CB 3.27Å; G284-F307 VanDerWaalsContact O-CE1 3.27Å; G284-F307 WeakPolarHBondContact O-CE1 3.44Å; L287-F307 HydrophobicContact CB-CE1 4.32Å; L287-F307 HydrophobicContact CD2-CD1 4.23Å; L287-F307 HydrophobicContact CD2-CE1 4.27Å; L287-F307 HydrophobicContact CG-CE1 4.31Å; Y291-F307 HydrophobicContact CD2-CZ 4.28Å; Y291-F307 HydrophobicContact CE2-CE1 4.15Å; Y291-F307 HydrophobicContact CE2-CZ 4.01Å; D305-F307 PolarHBondContact O-N 3.21Å; D305-F307 VanDerWaalsContact O-N 3.13Å; F307-D311 HydrophobicContact CB-CB 4.25Å; F307-Q314 HydrophobicContact CB-CB 4.34Å; F307-Q314 HydrophobicContact CD1-CB 3.68Å; F307-Q314 HydrophobicContact CD1-CG 4.49Å; F307-Q314 HydrophobicContact CD2-CB 3.96Å; F307-Q314 HydrophobicContact CE1-CB 3.95Å; F307-Q314 HydrophobicContact CE2-CB 4.22Å; F307-Q314 WeakPolarHBondContact CE2-O 3.46Å; F307-Q314 HydrophobicContact CG-CB 3.69Å; F307-Q314 HydrophobicContact CZ-CB 4.21Å; F307-W315 HydrophobicContact CB-CG 4.35Å; F307-W315 HydrophobicContact CD2-CG 4.25Å; F307-W315 PolarHBondContact O-NE1 2.91Å; F307-F318 HydrophobicContact CE2-CB 3.37Å; F307-F318 AromaticContact CE2-CD1 3.92Å; F307-F318 HydrophobicContact CE2-CD1 3.92Å; F307-F318 AromaticContact CE2-CG 3.73Å; F307-F318 HydrophobicContact CE2-CG 3.73Å; F307-F318 HydrophobicContact CZ-CB 3.81Å; F307-F318 HydrophobicContact CZ-CD1 4.49Å; F307-F318 HydrophobicContact CZ-CD2 4.46Å; F307-F318 HydrophobicContact CZ-CG 4.02Å
308D98.3Very high98.4Very high16 Ų1629.7 Ų29.79%0.08615%0.148CC..  trans-56.8147.5177.9177.370.3000112.1S260 F263 Y268 D310 D311 W315S260-D308 WeakPolarHBondContact CA-OD1 3.26Å; S260-D308 WeakPolarHBondContact CB-OD1 3.39Å; S260-D308 WeakPolarHBondContact OG-CA 3.22Å; S260-D308 PolarHBondContact OG-OD1 3.32Å; F263-D308 HydrophobicContact CB-CB 3.9Å; F263-D308 HydrophobicContact CD1-CB 3.87Å; F263-D308 HydrophobicContact CD2-CB 3.84Å; F263-D308 HydrophobicContact CE1-CB 4.28Å; F263-D308 HydrophobicContact CE2-CB 4.24Å; F263-D308 HydrophobicContact CG-CB 3.61Å; F263-D308 HydrophobicContact CZ-CB 4.43Å; Y268-D308 HydrophobicContact CE1-CB 4.3Å; Y268-D308 PolarHBondContact OH-N 3.33Å; D308-D310 PolarHBondContact O-N 2.89Å; D308-D310 PolarHBondContact OD2-N 2.78Å; D308-D311 HydrophobicContact CB-CB 4.05Å; D308-D311 PolarHBondContact O-N 3.27Å; D308-W315 PolarHBondContact O-NE1 2.95Å
309Q97Very high98.4Very high21 Ų2129.7 Ų29.710%0.09815%0.151CC..THydrogen-bonded Turntrans-54.4-17.9-178.668.4-164.6-37.600115S260 D330 L331 R338S260-Q309 PolarHBondContact OG-N 2.83Å; Q309-D330 HydrophobicContact CB-CB 4.01Å; Q309-L331 WeakPolarHBondContact O-CD1 3.43Å; Q309-R338 PolarHBondContact O-NH2 3.48Å
310D97.3Very high98.5Very high76 Ų7631.4 Ų31.441%0.40617%0.17SC..THydrogen-bonded Turntrans-117.92.9174.6-70.7-44.7000114.3H55 D308 W312 R338H55-D310 IonicContact NE2-OD1 3.38Å; H55-D310 IonicContact NE2-OD2 2.75Å; D308-D310 PolarHBondContact O-N 2.89Å; D308-D310 PolarHBondContact OD2-N 2.78Å; D310-W312 PolarHBondContact O-N 3.39Å; D310-R338 IonicContact OD1-CZ 2.65Å; D310-R338 IonicContact OD1-NH1 3.39Å; D310-R338 IonicContact OD1-NH2 3.61Å; D310-R338 PolarHBondContact OD1-NH2 2.8Å
311D97.6Very high98.5Very high31 Ų3134.3 Ų34.317%0.16619%0.19CC..  trans-81.752.2176.7-165.8-2.3000112.4Y268 F307 D308 E313 Q314 W315Y268-D311 WeakPolarHBondContact OH-CB 3.38Å; Y268-D311 PolarHBondContact OH-OD2 3.44Å; F307-D311 HydrophobicContact CB-CB 4.25Å; D308-D311 HydrophobicContact CB-CB 4.05Å; D308-D311 PolarHBondContact O-N 3.27Å; D311-E313 PolarHBondContact O-N 3.41Å; D311-Q314 VanDerWaalsContact CG-CG 3.45Å; D311-Q314 PolarHBondContact O-N 2.7Å; D311-Q314 WeakPolarHBondContact OD1-CG 3.37Å; D311-Q314 WeakPolarHBondContact OD2-CG 3.34Å; D311-W315 VanDerWaalsContact O-CD1 3.24Å; D311-W315 PolarHBondContact O-N 3.24Å
312W98.4Very high98.4Very high30 Ų3032.2 Ų32.211%0.11418%0.182CC..Hα-helixtrans-50.5-31.5-174.8-69.1101000114.5D310 A316 L331 Q341 A342 K345 A347D310-W312 PolarHBondContact O-N 3.39Å; W312-A316 WeakPolarHBondContact O-CB 3.5Å; W312-A316 PolarHBondContact O-N 3.47Å; W312-A316 VanDerWaalsContact O-N 3.14Å; W312-L331 HydrophobicContact CD2-CD1 4.09Å; W312-L331 HydrophobicContact CE3-CD1 3.72Å; W312-L331 HydrophobicContact CH2-CD1 3.62Å; W312-L331 HydrophobicContact CH2-CG 4.03Å; W312-L331 HydrophobicContact CZ2-CD1 4Å; W312-L331 HydrophobicContact CZ3-CD1 3.45Å; W312-L331 VanDerWaalsContact CZ3-CD1 3.45Å; W312-L331 HydrophobicContact CZ3-CD2 4.1Å; W312-L331 HydrophobicContact CZ3-CG 3.89Å; W312-Q341 HydrophobicContact CH2-CB 4.23Å; W312-Q341 HydrophobicContact CH2-CG 3.93Å; W312-Q341 VanDerWaalsContact CZ2-CD 3.4Å; W312-Q341 HydrophobicContact CZ2-CG 4.01Å; W312-Q341 HydrophobicContact CZ3-CG 4.35Å; W312-A342 HydrophobicContact CH2-CB 4.06Å; W312-A342 HydrophobicContact CZ3-CB 3.63Å; W312-K345 HydrophobicContact CB-CD 3.99Å; W312-K345 HydrophobicContact CD2-CD 3.67Å; W312-K345 HydrophobicContact CE3-CB 4.49Å; W312-K345 HydrophobicContact CE3-CD 3.49Å; W312-K345 VanDerWaalsContact CE3-CD 3.49Å; W312-K345 HydrophobicContact CG-CD 3.91Å; W312-K345 HydrophobicContact CZ3-CD 4.21Å; W312-A347 HydrophobicContact CE3-CB 3.87Å; W312-A347 HydrophobicContact CZ3-CB 3.94Å
313E98.1Very high98.4Very high122 Ų12238.9 Ų38.957%0.5722%0.217SC*.Hα-helixtrans-68.2-46.6179.9-172.3-178.3159.200111.2D311 A316 K317D311-E313 PolarHBondContact O-N 3.41Å; E313-A316 PolarHBondContact O-N 3.44Å; E313-K317 HydrophobicContact CG-CD 4.12Å; E313-K317 WeakPolarHBondContact O-CB 3.39Å; E313-K317 WeakPolarHBondContact O-CG 3.37Å; E313-K317 PolarHBondContact O-N 3.34Å; E313-K317 VanDerWaalsContact OE1-CE 3.26Å; E313-K317 WeakPolarHBondContact OE1-CE 3.46Å; E313-K317 IonicContact OE1-NZ 3.71Å; E313-K317 PolarHBondContact OE1-NZ 2.79Å
314Q98.6Very high98.4Very high30 Ų3039.2 Ų39.214%0.1422%0.219CC..Hα-helixtrans-70.8-36.9-179.8-60.4-66.742.200112G284 E285 F307 D311 K317 F318G284-Q314 VanDerWaalsContact C-NE2 3.27Å; G284-Q314 VanDerWaalsContact CA-NE2 3.31Å; E285-Q314 VanDerWaalsContact N-NE2 3.16Å; F307-Q314 HydrophobicContact CB-CB 4.34Å; F307-Q314 HydrophobicContact CD1-CB 3.68Å; F307-Q314 HydrophobicContact CD1-CG 4.49Å; F307-Q314 HydrophobicContact CD2-CB 3.96Å; F307-Q314 HydrophobicContact CE1-CB 3.95Å; F307-Q314 HydrophobicContact CE2-CB 4.22Å; F307-Q314 WeakPolarHBondContact CE2-O 3.46Å; F307-Q314 HydrophobicContact CG-CB 3.69Å; F307-Q314 HydrophobicContact CZ-CB 4.21Å; D311-Q314 VanDerWaalsContact CG-CG 3.45Å; D311-Q314 PolarHBondContact O-N 2.7Å; D311-Q314 WeakPolarHBondContact OD1-CG 3.37Å; D311-Q314 WeakPolarHBondContact OD2-CG 3.34Å; Q314-K317 PolarHBondContact O-N 2.73Å; Q314-F318 VanDerWaalsContact O-CB 3.29Å; Q314-F318 WeakPolarHBondContact O-CB 3.49Å; Q314-F318 PolarHBondContact O-N 3.26Å
315W98.8Very high98.4Very high0 Ų039.1 Ų39.10%022%0.219CC..Hα-helixtrans-52.9-55.6169.4-81.795.3000112D305 P306 F307 D308 D311 K317 F318 T319 I326 V327 L331 A347 C348D305-W315 HydrophobicContact CB-CH2 4.42Å; D305-W315 HydrophobicContact CB-CZ2 4.35Å; D305-W315 VanDerWaalsContact OD1-CH2 3.23Å; D305-W315 WeakPolarHBondContact OD1-CH2 3.43Å; D305-W315 WeakPolarHBondContact OD1-CZ2 3.24Å; P306-W315 HydrophobicContact CG-CD2 4.44Å; P306-W315 HydrophobicContact CG-CE3 4.09Å; P306-W315 HydrophobicContact CG-CH2 4.32Å; P306-W315 HydrophobicContact CG-CZ3 4.04Å; F307-W315 HydrophobicContact CB-CG 4.35Å; F307-W315 HydrophobicContact CD2-CG 4.25Å; F307-W315 PolarHBondContact O-NE1 2.91Å; D308-W315 PolarHBondContact O-NE1 2.95Å; D311-W315 VanDerWaalsContact O-CD1 3.24Å; D311-W315 PolarHBondContact O-N 3.24Å; W315-K317 PolarHBondContact O-N 3.37Å; W315-F318 PolarHBondContact O-N 2.76Å; W315-T319 WeakPolarHBondContact O-CB 3.47Å; W315-T319 PolarHBondContact O-N 3.26Å; W315-T319 PolarHBondContact O-OG1 2.79Å; W315-T319 VanDerWaalsContact O-OG1 3.07Å; W315-I326 HydrophobicContact CE3-CG2 3.97Å; W315-I326 HydrophobicContact CZ3-CG2 3.76Å; W315-V327 WeakPolarHBondContact CH2-O 3.48Å; W315-L331 HydrophobicContact CD2-CD1 4.38Å; W315-L331 HydrophobicContact CD2-CD2 3.69Å; W315-L331 HydrophobicContact CD2-CG 4.48Å; W315-L331 HydrophobicContact CE3-CD2 3.69Å; W315-L331 HydrophobicContact CG-CD1 4.41Å; W315-L331 HydrophobicContact CG-CD2 4.26Å; W315-L331 HydrophobicContact CH2-CB 3.92Å; W315-L331 HydrophobicContact CH2-CD2 3.91Å; W315-L331 HydrophobicContact CH2-CG 4.5Å; W315-L331 HydrophobicContact CZ2-CB 3.64Å; W315-L331 HydrophobicContact CZ2-CD1 4.46Å; W315-L331 HydrophobicContact CZ2-CD2 3.99Å; W315-L331 HydrophobicContact CZ2-CG 4.23Å; W315-L331 HydrophobicContact CZ3-CD2 3.79Å; W315-A347 CarbonylContact C-O 3.56Å; W315-A347 HydrophobicContact CB-CB 3.97Å; W315-C348 HydrophobicContact CE3-CB 4.04Å; W315-C348 HydrophobicContact CZ3-CB 3.83Å
316A98.8Very high98.4Very high28 Ų2839.1 Ų39.123%0.23122%0.218CC..Hα-helixtrans-63.6-42.9-178.100000112.5W312 E313 A320 K345W312-A316 WeakPolarHBondContact O-CB 3.5Å; W312-A316 PolarHBondContact O-N 3.47Å; W312-A316 VanDerWaalsContact O-N 3.14Å; E313-A316 PolarHBondContact O-N 3.44Å; A316-A320 VanDerWaalsContact O-CB 3.32Å; A316-A320 WeakPolarHBondContact O-CB 3.25Å; A316-A320 PolarHBondContact O-N 2.98Å; A316-K345 WeakPolarHBondContact CB-O 3.34Å
317K98.6Very high98.4Very high113 Ų11339.1 Ų39.149%0.49122%0.218SC..Hα-helixtrans-60.4-46.5176.8-79.7172.7169.4174.10112E313 Q314 W315 S321E313-K317 HydrophobicContact CG-CD 4.12Å; E313-K317 WeakPolarHBondContact O-CB 3.39Å; E313-K317 WeakPolarHBondContact O-CG 3.37Å; E313-K317 PolarHBondContact O-N 3.34Å; E313-K317 VanDerWaalsContact OE1-CE 3.26Å; E313-K317 WeakPolarHBondContact OE1-CE 3.46Å; E313-K317 IonicContact OE1-NZ 3.71Å; E313-K317 PolarHBondContact OE1-NZ 2.79Å; Q314-K317 PolarHBondContact O-N 2.73Å; W315-K317 PolarHBondContact O-N 3.37Å; K317-S321 PolarHBondContact O-N 3.14Å
318F98.8Very high98.4Very high3 Ų339 Ų391%0.01322%0.218CC..Hα-helixtrans-69.7-47.7-177.9-176.4-115.5000111.8Y291 R292 I295 I303 P306 F307 Q314 W315 A320 S321 V322 I326Y291-F318 VanDerWaalsContact CB-CZ 3.42Å; Y291-F318 HydrophobicContact CD2-CE1 4.11Å; Y291-F318 HydrophobicContact CD2-CE2 4.05Å; Y291-F318 AromaticContact CD2-CZ 3.83Å; Y291-F318 HydrophobicContact CD2-CZ 3.83Å; Y291-F318 HydrophobicContact CG-CE2 4.38Å; Y291-F318 HydrophobicContact CG-CZ 4.04Å; R292-F318 HydrophobicContact CG-CE2 4.21Å; I295-F318 HydrophobicContact CD1-CZ 4.12Å; I303-F318 HydrophobicContact CD1-CE1 4.39Å; I303-F318 HydrophobicContact CD1-CZ 4.21Å; P306-F318 HydrophobicContact CB-CD1 4.29Å; P306-F318 HydrophobicContact CB-CE1 4.32Å; P306-F318 HydrophobicContact CG-CD1 4.22Å; F307-F318 HydrophobicContact CE2-CB 3.37Å; F307-F318 AromaticContact CE2-CD1 3.92Å; F307-F318 HydrophobicContact CE2-CD1 3.92Å; F307-F318 AromaticContact CE2-CG 3.73Å; F307-F318 HydrophobicContact CE2-CG 3.73Å; F307-F318 HydrophobicContact CZ-CB 3.81Å; F307-F318 HydrophobicContact CZ-CD1 4.49Å; F307-F318 HydrophobicContact CZ-CD2 4.46Å; F307-F318 HydrophobicContact CZ-CG 4.02Å; Q314-F318 VanDerWaalsContact O-CB 3.29Å; Q314-F318 WeakPolarHBondContact O-CB 3.49Å; Q314-F318 PolarHBondContact O-N 3.26Å; W315-F318 PolarHBondContact O-N 2.76Å; F318-A320 PolarHBondContact O-N 3.42Å; F318-S321 WeakPolarHBondContact O-CA 3.46Å; F318-S321 WeakPolarHBondContact O-CB 3.41Å; F318-S321 PolarHBondContact O-N 3.19Å; F318-S321 PolarHBondContact O-OG 3Å; F318-V322 HydrophobicContact CD2-CG1 4.44Å; F318-V322 HydrophobicContact CE1-CG2 4.39Å; F318-V322 HydrophobicContact CE2-CG1 3.92Å; F318-V322 HydrophobicContact CZ-CG1 4.08Å; F318-V322 HydrophobicContact CZ-CG2 4.47Å; F318-V322 PolarHBondContact O-N 3.38Å; F318-I326 HydrophobicContact CD1-CD1 3.91Å; F318-I326 HydrophobicContact CE1-CD1 3.5Å; F318-I326 VanDerWaalsContact CE1-CD1 3.5Å
319T98.8Very high98.4Very high20 Ų2038.2 Ų38.212%0.12321%0.214CC..Hα-helixtrans-57.5-37.4177.3-65.80000112W315 S321 A347W315-T319 WeakPolarHBondContact O-CB 3.47Å; W315-T319 PolarHBondContact O-N 3.26Å; W315-T319 PolarHBondContact O-OG1 2.79Å; W315-T319 VanDerWaalsContact O-OG1 3.07Å; T319-S321 PolarHBondContact O-N 3Å; T319-A347 WeakPolarHBondContact CB-O 3.49Å; T319-A347 PolarHBondContact OG1-O 3.14Å
320A98.6Very high98.3Very high90 Ų9037.3 Ų37.374%0.74421%0.21SC*.THydrogen-bonded Turntrans-69.4-16.5174.900000114.2A316 F318A316-A320 VanDerWaalsContact O-CB 3.32Å; A316-A320 WeakPolarHBondContact O-CB 3.25Å; A316-A320 PolarHBondContact O-N 2.98Å; F318-A320 PolarHBondContact O-N 3.42Å
321S98.4Very high98.3Very high60 Ų6033.7 Ų33.742%0.4219%0.19SC..THydrogen-bonded Turntrans-99.7-4.7-174.275.70000114.7R292 K317 F318 T319R292-S321 PolarHBondContact NH1-OG 2.8Å; K317-S321 PolarHBondContact O-N 3.14Å; F318-S321 WeakPolarHBondContact O-CA 3.46Å; F318-S321 WeakPolarHBondContact O-CB 3.41Å; F318-S321 PolarHBondContact O-N 3.19Å; F318-S321 PolarHBondContact O-OG 3Å; T319-S321 PolarHBondContact O-N 3Å
322V98.4Very high98.4Very high29 Ų2932.2 Ų32.218%0.17618%0.183CC..  trans-136.9153.8-173.8-58.30000111.8R292 I295 F318 I324 I326R292-V322 HydrophobicContact CG-CG1 4.37Å; I295-V322 HydrophobicContact CD1-CB 4.37Å; I295-V322 HydrophobicContact CD1-CG1 3.86Å; F318-V322 HydrophobicContact CD2-CG1 4.44Å; F318-V322 HydrophobicContact CE1-CG2 4.39Å; F318-V322 HydrophobicContact CE2-CG1 3.92Å; F318-V322 HydrophobicContact CZ-CG1 4.08Å; F318-V322 HydrophobicContact CZ-CG2 4.47Å; F318-V322 PolarHBondContact O-N 3.38Å; V322-I324 HydrophobicContact CB-CG1 4.14Å; V322-I324 HydrophobicContact CG2-CG1 3.79Å; V322-I326 HydrophobicContact CG2-CD1 4Å; V322-I326 HydrophobicContact CG2-CG1 4.11Å
323D97.3Very high98.3Very high143 Ų14330.8 Ų30.877%0.76518%0.177SC*.SBendtrans-105.913.3179-164.823.6000113.3R440D323-R440 PolarHBondContact O-NH1 2.87Å
324I98.8Very high98.3Very high6 Ų625 Ų253%0.03115%0.15CC..SBendtrans-87.2174177.965.8156.5000111.5I295 I303 V322 I326 N349 R440I295-I324 HydrophobicContact CD1-CD1 3.56Å; I295-I324 HydrophobicContact CD1-CG1 4.07Å; I295-I324 HydrophobicContact CG1-CD1 3.96Å; I295-I324 HydrophobicContact CG2-CG2 4.1Å; I303-I324 HydrophobicContact CB-CD1 4.24Å; I303-I324 HydrophobicContact CD1-CD1 3.75Å; I303-I324 HydrophobicContact CG1-CD1 3.66Å; V322-I324 HydrophobicContact CB-CG1 4.14Å; V322-I324 HydrophobicContact CG2-CG1 3.79Å; I324-I326 HydrophobicContact CD1-CD1 3.94Å; I324-I326 HydrophobicContact CG1-CD1 3.92Å; I324-N349 PolarHBondContact O-ND2 2.89Å; I324-R440 PolarHBondContact O-NH2 3.44Å
325Q98.9Very high98.1Very high0 Ų025.4 Ų25.40%015%0.153CC..EExtended strand (participates in β ladder)trans-73129.1169-177.1171.2-89.800110.3Q301 S302 I303 V327 N349 C350 R440Q301-Q325 WeakPolarHBondContact O-CB 3.48Å; Q301-Q325 PolarHBondContact O-N 3.25Å; S302-Q325 CarbonylContact C-O 3.58Å; S302-Q325 VanDerWaalsContact CA-O 3.26Å; S302-Q325 WeakPolarHBondContact CA-O 3.38Å; S302-Q325 PolarHBondContact OG-NE2 2.84Å; I303-Q325 PolarHBondContact N-O 3.42Å; Q325-V327 HydrophobicContact CG-CG2 3.85Å; Q325-N349 WeakPolarHBondContact CA-OD1 3.24Å; Q325-C350 VanDerWaalsContact CD-SG 3.57Å; Q325-C350 HydrophobicContact CG-CB 3.49Å; Q325-C350 VanDerWaalsContact CG-CB 3.49Å; Q325-R440 HydrophobicContact CB-CG 4.48Å
326I98.9Very high97.9Very high0 Ų027.3 Ų27.30%017%0.166CC..EExtended strand (participates in β ladder)trans-115.7115.9171.1-56.9-58.5000107.6I303 P306 W315 F318 V322 I324 C348 N349 C350I303-I326 HydrophobicContact CB-CD1 4.21Å; I303-I326 CarbonylContact O-C 3.52Å; I303-I326 VanDerWaalsContact O-CA 3.31Å; I303-I326 WeakPolarHBondContact O-CA 3.23Å; P306-I326 HydrophobicContact CG-CG2 4.21Å; W315-I326 HydrophobicContact CE3-CG2 3.97Å; W315-I326 HydrophobicContact CZ3-CG2 3.76Å; F318-I326 HydrophobicContact CD1-CD1 3.91Å; F318-I326 HydrophobicContact CE1-CD1 3.5Å; F318-I326 VanDerWaalsContact CE1-CD1 3.5Å; V322-I326 HydrophobicContact CG2-CD1 4Å; V322-I326 HydrophobicContact CG2-CG1 4.11Å; I324-I326 HydrophobicContact CD1-CD1 3.94Å; I324-I326 HydrophobicContact CG1-CD1 3.92Å; I326-C348 HydrophobicContact CB-CB 4.35Å; I326-C348 HydrophobicContact CG2-CB 3.87Å; I326-C348 WeakPolarHBondContact O-CB 3.38Å; I326-N349 PolarHBondContact N-OD1 2.97Å; I326-N349 PolarHBondContact O-N 2.84Å; I326-N349 PolarHBondContact O-OD1 2.87Å; I326-C350 PolarHBondContact O-N 3.47Å
327V98.9Very high97.7Very high0 Ų032.5 Ų32.50%018%0.183CC..EExtended strand (participates in β ladder)trans-101.6126.3-172.9-168.70000109.3S302 I303 E304 D305 W315 Q325 C350 L352S302-V327 WeakPolarHBondContact OG-CG2 3.41Å; I303-V327 PolarHBondContact O-N 2.92Å; E304-V327 WeakPolarHBondContact CA-O 3.36Å; E304-V327 HydrophobicContact CB-CB 3.76Å; E304-V327 HydrophobicContact CB-CG1 4.4Å; E304-V327 HydrophobicContact CB-CG2 4.33Å; E304-V327 HydrophobicContact CG-CB 3.95Å; E304-V327 HydrophobicContact CG-CG1 4.12Å; D305-V327 PolarHBondContact N-O 3.07Å; D305-V327 VanDerWaalsContact N-O 3.12Å; W315-V327 WeakPolarHBondContact CH2-O 3.48Å; Q325-V327 HydrophobicContact CG-CG2 3.85Å; V327-C350 CarbonylContact C-O 3.56Å; V327-C350 WeakPolarHBondContact CA-O 3.45Å; V327-C350 HydrophobicContact CB-CB 4.35Å; V327-C350 HydrophobicContact CG1-CB 4.41Å; V327-C350 HydrophobicContact CG2-CB 3.98Å; V327-L352 HydrophobicContact CG1-CB 3.72Å; V327-L352 HydrophobicContact CG1-CD1 4.07Å
328G98.7Very high97.7Very high0 Ų028.4 Ų28.40%016%0.164CC..EExtended strand (participates in β ladder)trans-93.2115.4169.100000111.1T332 C350 L352G328-T332 PolarHBondContact O-OG1 3.38Å; G328-C350 PolarHBondContact N-O 3.21Å; G328-L352 PolarHBondContact O-N 2.84Å
329D97.9Very high97.7Very high1 Ų128.2 Ų28.21%0.00516%0.164CC..SBendtrans-105.3-84.5171.8174.927.6000110.2E304 D305 L331 T332 V333 L352 K354 Q357E304-D329 HydrophobicContact CG-CB 3.95Å; E304-D329 WeakPolarHBondContact OE1-CB 3.28Å; D305-D329 PolarHBondContact OD1-N 3.43Å; D305-D329 WeakPolarHBondContact OD2-CB 3.45Å; D329-L331 PolarHBondContact O-N 3.38Å; D329-T332 PolarHBondContact O-N 2.78Å; D329-T332 PolarHBondContact O-OG1 3.1Å; D329-V333 WeakPolarHBondContact O-CA 3.43Å; D329-V333 PolarHBondContact O-N 2.96Å; D329-L352 HydrophobicContact CB-CB 3.78Å; D329-L352 HydrophobicContact CB-CD2 3.63Å; D329-L352 HydrophobicContact CB-CG 4.33Å; D329-L352 WeakPolarHBondContact OD1-CD2 3.4Å; D329-K354 WeakPolarHBondContact OD1-CD 3.42Å; D329-K354 IonicContact OD1-NZ 3.03Å; D329-K354 PolarHBondContact OD1-NZ 2.62Å; D329-K354 IonicContact OD2-NZ 2.85Å; D329-K354 PolarHBondContact OD2-NZ 3.39Å; D329-Q357 PolarHBondContact OD1-NE2 3.19Å
330D95.4Very high97.6Very high2 Ų230.9 Ų30.91%0.01117%0.174CC..THydrogen-bonded Turntrans-63.2-27.4178-71.3-27000111.9G53 D305 Q309 T332 V333G53-D330 WeakPolarHBondContact CA-OD1 3.19Å; G53-D330 PolarHBondContact N-OD1 3.49Å; D305-D330 PolarHBondContact OD1-N 2.96Å; D305-D330 VanDerWaalsContact OD2-CB 3.29Å; D305-D330 WeakPolarHBondContact OD2-CB 3.5Å; D305-D330 PolarHBondContact OD2-N 2.67Å; Q309-D330 HydrophobicContact CB-CB 4.01Å; D330-T332 VanDerWaalsContact C-N 3.25Å; D330-T332 PolarHBondContact O-N 3.37Å; D330-V333 WeakPolarHBondContact O-CG1 3.41Å
331L98.1Very high97.6Very high0 Ų029.7 Ų29.70%015%0.154CC..THydrogen-bonded Turntrans-57.1-39.8171.3-178.369.8000112.3Q309 W312 W315 D329 R338 A342 A347 C348Q309-L331 WeakPolarHBondContact O-CD1 3.43Å; W312-L331 HydrophobicContact CD2-CD1 4.09Å; W312-L331 HydrophobicContact CE3-CD1 3.72Å; W312-L331 HydrophobicContact CH2-CD1 3.62Å; W312-L331 HydrophobicContact CH2-CG 4.03Å; W312-L331 HydrophobicContact CZ2-CD1 4Å; W312-L331 HydrophobicContact CZ3-CD1 3.45Å; W312-L331 VanDerWaalsContact CZ3-CD1 3.45Å; W312-L331 HydrophobicContact CZ3-CD2 4.1Å; W312-L331 HydrophobicContact CZ3-CG 3.89Å; W315-L331 HydrophobicContact CD2-CD1 4.38Å; W315-L331 HydrophobicContact CD2-CD2 3.69Å; W315-L331 HydrophobicContact CD2-CG 4.48Å; W315-L331 HydrophobicContact CE3-CD2 3.69Å; W315-L331 HydrophobicContact CG-CD1 4.41Å; W315-L331 HydrophobicContact CG-CD2 4.26Å; W315-L331 HydrophobicContact CH2-CB 3.92Å; W315-L331 HydrophobicContact CH2-CD2 3.91Å; W315-L331 HydrophobicContact CH2-CG 4.5Å; W315-L331 HydrophobicContact CZ2-CB 3.64Å; W315-L331 HydrophobicContact CZ2-CD1 4.46Å; W315-L331 HydrophobicContact CZ2-CD2 3.99Å; W315-L331 HydrophobicContact CZ2-CG 4.23Å; W315-L331 HydrophobicContact CZ3-CD2 3.79Å; D329-L331 PolarHBondContact O-N 3.38Å; L331-R338 PolarHBondContact O-NE 2.96Å; L331-A342 HydrophobicContact CD2-CB 4.27Å; L331-A347 HydrophobicContact CD2-CB 3.96Å; L331-C348 HydrophobicContact CD2-CB 4.46Å
332T98.3Very high97.6Very high0 Ų026.8 Ų26.80%013%0.134CC..THydrogen-bonded Turntrans-112.5-25.1-169.269.90000113.8G328 D329 D330 T334 N335 I339 A342 L351G328-T332 PolarHBondContact O-OG1 3.38Å; D329-T332 PolarHBondContact O-N 2.78Å; D329-T332 PolarHBondContact O-OG1 3.1Å; D330-T332 VanDerWaalsContact C-N 3.25Å; D330-T332 PolarHBondContact O-N 3.37Å; T332-T334 PolarHBondContact O-N 3.31Å; T332-N335 WeakPolarHBondContact O-CB 3.46Å; T332-N335 PolarHBondContact O-N 3.48Å; T332-I339 HydrophobicContact CG2-CG1 4.32Å; T332-A342 HydrophobicContact CG2-CB 4.2Å; T332-L351 WeakPolarHBondContact OG1-CD1 3.35Å
333V96.9Very high97.6Very high0 Ų027.1 Ų27.10%014%0.135CC..THydrogen-bonded Turntrans42.636.9-179.4-680000113.6H55 E56 D329 D330 N335 Q357H55-V333 HydrophobicContact CB-CG1 4.39Å; H55-V333 HydrophobicContact CB-CG2 3.71Å; E56-V333 HydrophobicContact CG-CB 4.05Å; E56-V333 HydrophobicContact CG-CG1 3.67Å; D329-V333 WeakPolarHBondContact O-CA 3.43Å; D329-V333 PolarHBondContact O-N 2.96Å; D330-V333 WeakPolarHBondContact O-CG1 3.41Å; V333-N335 HydrophobicContact CG2-CB 3.83Å; V333-N335 PolarHBondContact O-N 3.05Å; V333-Q357 VanDerWaalsContact C-OE1 3.27Å; V333-Q357 WeakPolarHBondContact O-CB 3.08Å
334T98.1Very high97.7Very high0 Ų026.8 Ų26.80%013%0.129CC..THydrogen-bonded Turntrans5223.1-174.3-47.40000113.4T332 L352 L353 K354 Q357 I358 A367T332-T334 PolarHBondContact O-N 3.31Å; T334-L352 PolarHBondContact OG1-O 2.84Å; T334-L353 HydrophobicContact CG2-CG 4.01Å; T334-K354 PolarHBondContact OG1-N 3.45Å; T334-K354 PolarHBondContact OG1-O 3.45Å; T334-Q357 PolarHBondContact OG1-OE1 2.9Å; T334-I358 HydrophobicContact CG2-CB 4.13Å; T334-I358 HydrophobicContact CG2-CG2 3.89Å; T334-A367 HydrophobicContact CG2-CB 3.98Å
335N95.3Very high97.7Very high38 Ų3831.1 Ų31.120%0.20315%0.148CC..  trans-99.6119.3-174.3-175.8-45.2000110.9T332 V333 K337 R338 I339 I358T332-N335 WeakPolarHBondContact O-CB 3.46Å; T332-N335 PolarHBondContact O-N 3.48Å; V333-N335 HydrophobicContact CG2-CB 3.83Å; V333-N335 PolarHBondContact O-N 3.05Å; N335-K337 PolarHBondContact O-N 3.26Å; N335-K337 VanDerWaalsContact O-N 3.08Å; N335-K337 WeakPolarHBondContact OD1-CB 3.37Å; N335-K337 PolarHBondContact OD1-N 2.75Å; N335-R338 HydrophobicContact CB-CB 4.49Å; N335-R338 PolarHBondContact O-N 3.17Å; N335-I339 VanDerWaalsContact O-CG1 3.31Å; N335-I339 WeakPolarHBondContact O-CG1 3.48Å; N335-I339 PolarHBondContact O-N 2.91Å; N335-I358 HydrophobicContact CB-CD1 4.36Å
336P94.1Very high97.7Very high41 Ų4138.8 Ų38.827%0.26618%0.181SC..Hα-helixtrans-52.9-33.7-178.7-29.736.2000115.2Q340 L370P336-Q340 VanDerWaalsContact O-CB 3.31Å; P336-Q340 WeakPolarHBondContact O-CB 3.47Å; P336-Q340 PolarHBondContact O-N 3.37Å; P336-L370 HydrophobicContact CB-CD2 4.16Å; P336-L370 WeakPolarHBondContact O-CD2 3.5Å
337K95.4Very high97.7Very high137 Ų13738.8 Ų38.860%0.59618%0.181SC*.Hα-helixtrans-67.3-44.8178.2-63.2-178.3-177.6177.80111.7E112 N335 Q340 Q341E112-K337 IonicContact OE1-NZ 3.87Å; E112-K337 PolarHBondContact OE1-NZ 3.36Å; N335-K337 PolarHBondContact O-N 3.26Å; N335-K337 VanDerWaalsContact O-N 3.08Å; N335-K337 WeakPolarHBondContact OD1-CB 3.37Å; N335-K337 PolarHBondContact OD1-N 2.75Å; K337-Q340 PolarHBondContact O-N 2.99Å; K337-Q341 PolarHBondContact O-N 2.75Å; K337-Q341 VanDerWaalsContact O-N 3.09Å
338R97.6Very high97.7Very high26 Ų2638.9 Ų38.910%0.09818%0.182CC..Hα-helixtrans-72.9-36.1178.4-66.9-159.373.5100.9-11.5111.8H55 Q309 D310 L331 N335 Q340 Q341 A342H55-R338 VanDerWaalsContact CD2-CZ 3.42Å; H55-R338 PolarHBondContact CD2-NH1 3.2Å; H55-R338 PolarHBondContact NE2-NH1 3.34Å; Q309-R338 PolarHBondContact O-NH2 3.48Å; D310-R338 IonicContact OD1-CZ 2.65Å; D310-R338 IonicContact OD1-NH1 3.39Å; D310-R338 IonicContact OD1-NH2 3.61Å; D310-R338 PolarHBondContact OD1-NH2 2.8Å; L331-R338 PolarHBondContact O-NE 2.96Å; N335-R338 HydrophobicContact CB-CB 4.49Å; N335-R338 PolarHBondContact O-N 3.17Å; R338-Q340 VanDerWaalsContact C-N 3.34Å; R338-Q340 PolarHBondContact O-N 3.1Å; R338-Q341 PolarHBondContact O-N 3.43Å; R338-A342 VanDerWaalsContact O-CB 3.26Å; R338-A342 WeakPolarHBondContact O-CB 3.33Å; R338-A342 PolarHBondContact O-N 3.38Å
339I98.6Very high97.7Very high0 Ų040.4 Ų40.40%019%0.19CC..Hα-helixtrans-57.9-49.2171.6-65.5165.2000110T332 N335 Q341 A342 V343 L351 A367 L370 W376T332-I339 HydrophobicContact CG2-CG1 4.32Å; N335-I339 VanDerWaalsContact O-CG1 3.31Å; N335-I339 WeakPolarHBondContact O-CG1 3.48Å; N335-I339 PolarHBondContact O-N 2.91Å; I339-Q341 VanDerWaalsContact C-N 3.35Å; I339-Q341 PolarHBondContact O-N 3.07Å; I339-A342 PolarHBondContact O-N 2.9Å; I339-A342 VanDerWaalsContact O-N 3.14Å; I339-V343 HydrophobicContact CG2-CG2 4.41Å; I339-V343 WeakPolarHBondContact O-CG2 3.14Å; I339-V343 PolarHBondContact O-N 3.37Å; I339-L351 HydrophobicContact CD1-CD1 3.86Å; I339-L351 HydrophobicContact CD1-CD2 3.88Å; I339-L351 HydrophobicContact CD1-CG 4.5Å; I339-L351 HydrophobicContact CG1-CD1 4.07Å; I339-A367 HydrophobicContact CD1-CB 3.69Å; I339-L370 HydrophobicContact CB-CD2 3.96Å; I339-L370 HydrophobicContact CG2-CD2 3.67Å; I339-L370 HydrophobicContact CG2-CG 3.85Å; I339-W376 HydrophobicContact CG2-CZ3 4.3Å
340Q98.1Very high97.7Very high75 Ų7540.4 Ų40.435%0.3519%0.19SC..Hα-helixtrans-58.4-45.8178-176.760.24900111.9P336 K337 R338 A342 V343 E344P336-Q340 VanDerWaalsContact O-CB 3.31Å; P336-Q340 WeakPolarHBondContact O-CB 3.47Å; P336-Q340 PolarHBondContact O-N 3.37Å; K337-Q340 PolarHBondContact O-N 2.99Å; R338-Q340 VanDerWaalsContact C-N 3.34Å; R338-Q340 PolarHBondContact O-N 3.1Å; Q340-A342 VanDerWaalsContact C-N 3.33Å; Q340-A342 PolarHBondContact O-N 3Å; Q340-V343 PolarHBondContact O-N 2.72Å; Q340-E344 WeakPolarHBondContact CG-OE1 3.29Å; Q340-E344 PolarHBondContact NE2-OE1 3.47Å; Q340-E344 WeakPolarHBondContact O-CG 3.46Å; Q340-E344 PolarHBondContact O-N 3.04Å
341Q98.4Very high97.9Very high65 Ų6540.3 Ų40.330%0.30419%0.189SC..Hα-helixtrans-60.9-41.3175.5-176.8-179.610.200112.3W312 K337 R338 I339 E344 K345W312-Q341 HydrophobicContact CH2-CB 4.23Å; W312-Q341 HydrophobicContact CH2-CG 3.93Å; W312-Q341 VanDerWaalsContact CZ2-CD 3.4Å; W312-Q341 HydrophobicContact CZ2-CG 4.01Å; W312-Q341 HydrophobicContact CZ3-CG 4.35Å; K337-Q341 PolarHBondContact O-N 2.75Å; K337-Q341 VanDerWaalsContact O-N 3.09Å; R338-Q341 PolarHBondContact O-N 3.43Å; I339-Q341 VanDerWaalsContact C-N 3.35Å; I339-Q341 PolarHBondContact O-N 3.07Å; Q341-E344 PolarHBondContact O-N 2.82Å; Q341-K345 HydrophobicContact CG-CD 4.03Å; Q341-K345 WeakPolarHBondContact O-CB 3.32Å; Q341-K345 WeakPolarHBondContact O-CG 3.41Å; Q341-K345 PolarHBondContact O-N 2.88Å
342A98.7Very high97.9Very high0 Ų040.3 Ų40.30%019%0.189CC..Hα-helixtrans-68.4-36.4179.300000112.2W312 L331 T332 R338 I339 Q340 K346 A347 W376W312-A342 HydrophobicContact CH2-CB 4.06Å; W312-A342 HydrophobicContact CZ3-CB 3.63Å; L331-A342 HydrophobicContact CD2-CB 4.27Å; T332-A342 HydrophobicContact CG2-CB 4.2Å; R338-A342 VanDerWaalsContact O-CB 3.26Å; R338-A342 WeakPolarHBondContact O-CB 3.33Å; R338-A342 PolarHBondContact O-N 3.38Å; I339-A342 PolarHBondContact O-N 2.9Å; I339-A342 VanDerWaalsContact O-N 3.14Å; Q340-A342 VanDerWaalsContact C-N 3.33Å; Q340-A342 PolarHBondContact O-N 3Å; A342-K346 WeakPolarHBondContact O-CA 3.41Å; A342-K346 PolarHBondContact O-N 2.87Å; A342-A347 HydrophobicContact CB-CB 4.14Å; A342-A347 PolarHBondContact O-N 2.82Å; A342-W376 HydrophobicContact CB-CH2 3.59Å; A342-W376 HydrophobicContact CB-CZ2 4.4Å; A342-W376 HydrophobicContact CB-CZ3 4.49Å
343V98.4Very high97.9Very high35 Ų3540.3 Ų40.321%0.21219%0.189CC..Hα-helixtrans-61.4-50.1170.4169.90000110.6I339 Q340 K345 K346 W376I339-V343 HydrophobicContact CG2-CG2 4.41Å; I339-V343 WeakPolarHBondContact O-CG2 3.14Å; I339-V343 PolarHBondContact O-N 3.37Å; Q340-V343 PolarHBondContact O-N 2.72Å; V343-K345 VanDerWaalsContact C-N 3.3Å; V343-K345 PolarHBondContact O-N 2.75Å; V343-K346 PolarHBondContact O-N 3.27Å; V343-K346 VanDerWaalsContact O-N 3.07Å; V343-W376 HydrophobicContact CB-CZ2 4.2Å; V343-W376 HydrophobicContact CG2-CD2 4.27Å; V343-W376 HydrophobicContact CG2-CH2 3.87Å; V343-W376 HydrophobicContact CG2-CZ2 3.5Å; V343-W376 VanDerWaalsContact CG2-CZ2 3.5Å; V343-W376 HydrophobicContact CG2-CZ3 4.41Å
344E98.4Very high98Very high136 Ų13640.9 Ų40.964%0.63619%0.192SC*.Hα-helixtrans-60.5-39.6-180-73.9167.2-166.200112.6Q340 Q341 K346Q340-E344 WeakPolarHBondContact CG-OE1 3.29Å; Q340-E344 PolarHBondContact NE2-OE1 3.47Å; Q340-E344 WeakPolarHBondContact O-CG 3.46Å; Q340-E344 PolarHBondContact O-N 3.04Å; Q341-E344 PolarHBondContact O-N 2.82Å; E344-K346 VanDerWaalsContact C-N 3.3Å
345K98.5Very high98Very high97 Ų9741.1 Ų41.142%0.42219%0.193SC..Hα-helixtrans-81.6-6.9178.1-70.5176.6173.6-70.90113.8W312 A316 Q341 V343 A347W312-K345 HydrophobicContact CB-CD 3.99Å; W312-K345 HydrophobicContact CD2-CD 3.67Å; W312-K345 HydrophobicContact CE3-CB 4.49Å; W312-K345 HydrophobicContact CE3-CD 3.49Å; W312-K345 VanDerWaalsContact CE3-CD 3.49Å; W312-K345 HydrophobicContact CG-CD 3.91Å; W312-K345 HydrophobicContact CZ3-CD 4.21Å; A316-K345 WeakPolarHBondContact CB-O 3.34Å; Q341-K345 HydrophobicContact CG-CD 4.03Å; Q341-K345 WeakPolarHBondContact O-CB 3.32Å; Q341-K345 WeakPolarHBondContact O-CG 3.41Å; Q341-K345 PolarHBondContact O-N 2.88Å; V343-K345 VanDerWaalsContact C-N 3.3Å; V343-K345 PolarHBondContact O-N 2.75Å; K345-A347 HydrophobicContact CB-CB 4.32Å; K345-A347 PolarHBondContact O-N 2.63Å
346K98.4Very high98.1Very high161 Ų16139.8 Ų39.870%0.719%0.186SC*.THydrogen-bonded Turntrans51.940.8-171.2-54.9-179.3179.7-177.20111.7A342 V343 E344A342-K346 WeakPolarHBondContact O-CA 3.41Å; A342-K346 PolarHBondContact O-N 2.87Å; V343-K346 PolarHBondContact O-N 3.27Å; V343-K346 VanDerWaalsContact O-N 3.07Å; E344-K346 VanDerWaalsContact C-N 3.3Å
347A98.7Very high98.2Very high0 Ų038 Ų380%017%0.174CC..  trans-73.4-37.7-17100000111.9W312 W315 T319 L331 A342 K345W312-A347 HydrophobicContact CE3-CB 3.87Å; W312-A347 HydrophobicContact CZ3-CB 3.94Å; W315-A347 CarbonylContact C-O 3.56Å; W315-A347 HydrophobicContact CB-CB 3.97Å; T319-A347 WeakPolarHBondContact CB-O 3.49Å; T319-A347 PolarHBondContact OG1-O 3.14Å; L331-A347 HydrophobicContact CD2-CB 3.96Å; A342-A347 HydrophobicContact CB-CB 4.14Å; A342-A347 PolarHBondContact O-N 2.82Å; K345-A347 HydrophobicContact CB-CB 4.32Å; K345-A347 PolarHBondContact O-N 2.63Å
348C98.8Very high98.3Very high3 Ų331.9 Ų31.92%0.0215%0.148CC..  trans-145.7-179.5176.863.50000110.3W315 I326 L331 W376W315-C348 HydrophobicContact CE3-CB 4.04Å; W315-C348 HydrophobicContact CZ3-CB 3.83Å; I326-C348 HydrophobicContact CB-CB 4.35Å; I326-C348 HydrophobicContact CG2-CB 3.87Å; I326-C348 WeakPolarHBondContact O-CB 3.38Å; L331-C348 HydrophobicContact CD2-CB 4.46Å; C348-W376 WeakPolarHBondContact O-CZ2 3.47Å; C348-W376 PolarHBondContact O-NE1 3.37Å; C348-W376 WeakPolarHBondContact SG-CH2 3.44Å; C348-W376 WeakPolarHBondContact SG-CZ3 3.4Å
349N98.8Very high98.3Very high32 Ų3230.7 Ų30.717%0.17114%0.144CC..SBendtrans-136.213.2-179.666.325.9000113.3I324 Q325 I326 W376 G377 R440I324-N349 PolarHBondContact O-ND2 2.89Å; Q325-N349 WeakPolarHBondContact CA-OD1 3.24Å; I326-N349 PolarHBondContact N-OD1 2.97Å; I326-N349 PolarHBondContact O-N 2.84Å; I326-N349 PolarHBondContact O-OD1 2.87Å; N349-W376 VanDerWaalsContact O-CA 3.27Å; N349-W376 WeakPolarHBondContact O-CA 3.39Å; N349-W376 WeakPolarHBondContact O-CB 3.13Å; N349-G377 PolarHBondContact O-N 2.91Å; N349-R440 PolarHBondContact ND2-NH2 3.35Å
350C98.9Very high98.3Very high0 Ų030.7 Ų30.70%014%0.144CC..EExtended strand (participates in β ladder)trans-149.2140.8173.5-178.10000109.9Q325 I326 V327 G328 G377Q325-C350 VanDerWaalsContact CD-SG 3.57Å; Q325-C350 HydrophobicContact CG-CB 3.49Å; Q325-C350 VanDerWaalsContact CG-CB 3.49Å; I326-C350 PolarHBondContact O-N 3.47Å; V327-C350 CarbonylContact C-O 3.56Å; V327-C350 WeakPolarHBondContact CA-O 3.45Å; V327-C350 HydrophobicContact CB-CB 4.35Å; V327-C350 HydrophobicContact CG1-CB 4.41Å; V327-C350 HydrophobicContact CG2-CB 3.98Å; G328-C350 PolarHBondContact N-O 3.21Å; C350-G377 VanDerWaalsContact CA-O 3.27Å; C350-G377 WeakPolarHBondContact CA-O 3.22Å; C350-G377 PolarHBondContact SG-O 3.03Å
351L98.9Very high98.4Very high0 Ų027.1 Ų27.10%013%0.127CC..EExtended strand (participates in β ladder)trans-91.7134.1170.8168.464.8000109.6T332 I339 L353 A367 A371 W376 G377 V378 M379T332-L351 WeakPolarHBondContact OG1-CD1 3.35Å; I339-L351 HydrophobicContact CD1-CD1 3.86Å; I339-L351 HydrophobicContact CD1-CD2 3.88Å; I339-L351 HydrophobicContact CD1-CG 4.5Å; I339-L351 HydrophobicContact CG1-CD1 4.07Å; L351-L353 HydrophobicContact CD2-CB 4.33Å; L351-L353 HydrophobicContact CD2-CD1 4.47Å; L351-L353 HydrophobicContact CG-CB 4.39Å; L351-A367 HydrophobicContact CD2-CB 4.21Å; L351-A371 HydrophobicContact CB-CB 3.85Å; L351-A371 HydrophobicContact CD2-CB 4.01Å; L351-W376 HydrophobicContact CB-CE3 4.5Å; L351-G377 PolarHBondContact N-O 3.19Å; L351-V378 HydrophobicContact CB-CG1 4.48Å; L351-V378 HydrophobicContact CB-CG2 4.31Å; L351-V378 HydrophobicContact CD2-CG1 4.28Å; L351-V378 HydrophobicContact CG-CG1 4.45Å; L351-V378 CarbonylContact O-C 3.57Å; L351-V378 WeakPolarHBondContact O-CA 3.42Å; L351-M379 PolarHBondContact O-N 2.88Å
352L98.9Very high98.4Very high0 Ų024.8 Ų24.80%012%0.117CC..EExtended strand (participates in β ladder)trans-85.8119.3156.8-160.581.4000109.3E304 V327 G328 D329 T334 K354 M379 K405E304-L352 WeakPolarHBondContact OE1-CD2 3.3Å; V327-L352 HydrophobicContact CG1-CB 3.72Å; V327-L352 HydrophobicContact CG1-CD1 4.07Å; G328-L352 PolarHBondContact O-N 2.84Å; D329-L352 HydrophobicContact CB-CB 3.78Å; D329-L352 HydrophobicContact CB-CD2 3.63Å; D329-L352 HydrophobicContact CB-CG 4.33Å; D329-L352 WeakPolarHBondContact OD1-CD2 3.4Å; T334-L352 PolarHBondContact OG1-O 2.84Å; L352-K354 HydrophobicContact CD2-CD 3.99Å; L352-K354 VanDerWaalsContact CD2-CE 3.43Å; L352-K354 HydrophobicContact CD2-CG 4.19Å; L352-M379 WeakPolarHBondContact CA-O 3.5Å; L352-M379 HydrophobicContact CD1-CB 3.96Å; L352-M379 HydrophobicContact CD1-CG 3.94Å; L352-M379 HydrophobicContact CD1-SD 3.88Å; L352-K405 HydrophobicContact CD1-CD 3.93Å; L352-K405 HydrophobicContact CD1-CG 4.2Å
353L98.9Very high98.4Very high0 Ų026.3 Ų26.30%013%0.125CC..EExtended strand (participates in β ladder)trans-101.6107.1-176.5-171160000110.1T334 L351 V355 S364 C368 V378 M379 S381 L395 L399T334-L353 HydrophobicContact CG2-CG 4.01Å; L351-L353 HydrophobicContact CD2-CB 4.33Å; L351-L353 HydrophobicContact CD2-CD1 4.47Å; L351-L353 HydrophobicContact CG-CB 4.39Å; L353-V355 HydrophobicContact CD2-CG1 3.89Å; L353-S364 WeakPolarHBondContact CD1-O 3.38Å; L353-C368 HydrophobicContact CD1-CB 3.61Å; L353-V378 HydrophobicContact CB-CG1 3.75Å; L353-V378 HydrophobicContact CD1-CG1 3.88Å; L353-M379 PolarHBondContact N-O 3.28Å; L353-S381 PolarHBondContact O-N 2.9Å; L353-L395 HydrophobicContact CD2-CD2 3.93Å; L353-L399 HydrophobicContact CD1-CD1 3.92Å
354K98.7Very high98.4Very high12 Ų1224.7 Ų24.75%0.05211%0.114CC..  trans-114.3108.5172.7-71.8166.9168.8165.20108.9D329 T334 L352 N356 Q357D329-K354 WeakPolarHBondContact OD1-CD 3.42Å; D329-K354 IonicContact OD1-NZ 3.03Å; D329-K354 PolarHBondContact OD1-NZ 2.62Å; D329-K354 IonicContact OD2-NZ 2.85Å; D329-K354 PolarHBondContact OD2-NZ 3.39Å; T334-K354 PolarHBondContact OG1-N 3.45Å; T334-K354 PolarHBondContact OG1-O 3.45Å; L352-K354 HydrophobicContact CD2-CD 3.99Å; L352-K354 VanDerWaalsContact CD2-CE 3.43Å; L352-K354 HydrophobicContact CD2-CG 4.19Å; K354-N356 PolarHBondContact O-N 3.17Å; K354-Q357 HydrophobicContact CB-CB 4.21Å; K354-Q357 HydrophobicContact CB-CG 3.57Å; K354-Q357 VanDerWaalsContact CD-CD 3.47Å; K354-Q357 HydrophobicContact CD-CG 3.95Å; K354-Q357 HydrophobicContact CG-CG 4.42Å; K354-Q357 WeakPolarHBondContact O-CB 3.48Å; K354-Q357 PolarHBondContact O-N 2.72Å
355V97.9Very high98.4Very high5 Ų518.7 Ų18.73%0.039%0.087CC..Hα-helixtrans-56.5-30.5-174.2-66.80000113.9L123 L353 G359 S364 L395L123-V355 HydrophobicContact CD1-CB 4.17Å; L123-V355 HydrophobicContact CD1-CG2 4.38Å; L123-V355 HydrophobicContact CD2-CG2 4.13Å; L353-V355 HydrophobicContact CD2-CG1 3.89Å; V355-G359 PolarHBondContact O-N 2.99Å; V355-S364 WeakPolarHBondContact CA-OG 3.18Å; V355-L395 HydrophobicContact CG1-CD2 3.38Å
356N97Very high98.4Very high11 Ų1118.3 Ų18.36%0.0599%0.087CC..Hα-helixtrans-81.1-17.5179.776.7-41.5000113.8V46 P47 L123 K354 I358 R383V46-N356 HydrophobicContact CG1-CB 4.39Å; P47-N356 HydrophobicContact CG-CB 4.32Å; P47-N356 PolarHBondContact O-ND2 3.29Å; L123-N356 VanDerWaalsContact CD2-CA 3.47Å; L123-N356 HydrophobicContact CD2-CB 3.42Å; L123-N356 VanDerWaalsContact CD2-CB 3.42Å; K354-N356 PolarHBondContact O-N 3.17Å; N356-I358 VanDerWaalsContact C-N 3.27Å; N356-I358 PolarHBondContact O-N 2.95Å; N356-R383 PolarHBondContact ND2-NH1 2.95Å; N356-R383 VanDerWaalsContact OD1-CD 3.27Å; N356-R383 WeakPolarHBondContact OD1-CD 3.36Å; N356-R383 WeakPolarHBondContact OD1-CG 3.42Å; N356-R383 PolarHBondContact OD1-NH1 2.62Å
357Q96.7Very high98.4Very high2 Ų210.7 Ų10.71%0.0095%0.053CC..Hα-helixtrans-68.3-29.6172.8-69.4-172.7-40.500111.9E56 A57 D329 V333 T334 K354E56-Q357 VanDerWaalsContact CD-CG 3.45Å; E56-Q357 HydrophobicContact CG-CB 4.13Å; E56-Q357 HydrophobicContact CG-CG 3.77Å; E56-Q357 PolarHBondContact OE1-NE2 2.68Å; A57-Q357 WeakPolarHBondContact CB-O 3.31Å; A57-Q357 PolarHBondContact N-O 3.01Å; D329-Q357 PolarHBondContact OD1-NE2 3.19Å; V333-Q357 VanDerWaalsContact C-OE1 3.27Å; V333-Q357 WeakPolarHBondContact O-CB 3.08Å; T334-Q357 PolarHBondContact OG1-OE1 2.9Å; K354-Q357 HydrophobicContact CB-CB 4.21Å; K354-Q357 HydrophobicContact CB-CG 3.57Å; K354-Q357 VanDerWaalsContact CD-CD 3.47Å; K354-Q357 HydrophobicContact CD-CG 3.95Å; K354-Q357 HydrophobicContact CG-CG 4.42Å; K354-Q357 WeakPolarHBondContact O-CB 3.48Å; K354-Q357 PolarHBondContact O-N 2.72Å
358I97.8Very high98.4Very high10 Ų1010.7 Ų10.75%0.0515%0.053CC..Hα-helixtrans-103.9-31.1177.1-161.456.8000112.9K114 T334 N335 N356 E363 S364K114-I358 WeakPolarHBondContact CD-O 3.49Å; K114-I358 WeakPolarHBondContact CE-O 3.31Å; K114-I358 PolarHBondContact NZ-O 2.7Å; T334-I358 HydrophobicContact CG2-CB 4.13Å; T334-I358 HydrophobicContact CG2-CG2 3.89Å; N335-I358 HydrophobicContact CB-CD1 4.36Å; N356-I358 VanDerWaalsContact C-N 3.27Å; N356-I358 PolarHBondContact O-N 2.95Å; I358-E363 HydrophobicContact CB-CB 4.46Å; I358-E363 HydrophobicContact CG1-CB 3.51Å; I358-E363 HydrophobicContact CG1-CG 4.33Å; I358-E363 HydrophobicContact CG2-CB 4.09Å; I358-S364 VanDerWaalsContact CG2-OG 3.24Å; I358-S364 WeakPolarHBondContact CG2-OG 3.35Å
359G97.4Very high98.4Very high0 Ų014.3 Ų14.30%07%0.069CC..  trans94.93.4166.100000116.8I122 L123 V355I122-G359 WeakPolarHBondContact CG2-O 3.33Å; L123-G359 WeakPolarHBondContact CA-O 3.2Å; L123-G359 PolarHBondContact N-O 2.95Å; V355-G359 PolarHBondContact O-N 2.99Å
360S98.8Very high98.4Very high0 Ų014.6 Ų14.60%07%0.07CC..SBendtrans-147.9155.1169.575.20000112.5E363 S364S360-E363 WeakPolarHBondContact CB-OE2 3.45Å; S360-E363 WeakPolarHBondContact OG-CB 3.27Å; S360-E363 VanDerWaalsContact OG-CG 3.32Å; S360-E363 WeakPolarHBondContact OG-CG 3.37Å; S360-E363 PolarHBondContact OG-N 2.89Å; S360-E363 PolarHBondContact OG-OE2 2.94Å; S360-S364 WeakPolarHBondContact O-CB 3.42Å; S360-S364 PolarHBondContact O-N 3.01Å; S360-S364 VanDerWaalsContact O-N 3.13Å; S360-S364 PolarHBondContact O-OG 3.49Å
361V98.9Very high98.4Very high0 Ų014.6 Ų14.60%07%0.07CC..Hα-helixtrans-63.8-42.9176.2174.70000110.6Q98 S126 L127 C130 S364 I365 F391Q98-V361 HydrophobicContact CG-CB 4.43Å; Q98-V361 HydrophobicContact CG-CG1 4.35Å; S126-V361 WeakPolarHBondContact OG-CG2 3.34Å; S126-V361 PolarHBondContact OG-N 3.1Å; L127-V361 HydrophobicContact CD2-CG2 3.68Å; L127-V361 HydrophobicContact CG-CG2 4.43Å; C130-V361 HydrophobicContact CB-CG2 4.36Å; V361-S364 WeakPolarHBondContact O-CB 3.37Å; V361-S364 PolarHBondContact O-N 3.26Å; V361-I365 HydrophobicContact CG1-CD1 3.8Å; V361-I365 HydrophobicContact CG1-CG1 4.36Å; V361-I365 WeakPolarHBondContact O-CG1 3.2Å; V361-I365 PolarHBondContact O-N 2.93Å; V361-F391 HydrophobicContact CG1-CZ 4.29Å; V361-F391 HydrophobicContact CG2-CE1 4.2Å; V361-F391 HydrophobicContact CG2-CE2 4.48Å; V361-F391 HydrophobicContact CG2-CZ 3.68Å
362T98.8Very high98.3Very high17 Ų1717.3 Ų17.310%0.1048%0.083CC..Hα-helixtrans-60.6-50-180-63.90000112.4E99 D102 S364 I365 Q366E99-T362 WeakPolarHBondContact CA-OG1 3.28Å; E99-T362 HydrophobicContact CB-CG2 4.16Å; E99-T362 HydrophobicContact CG-CG2 4Å; D102-T362 WeakPolarHBondContact OD2-CB 3.02Å; D102-T362 PolarHBondContact OD2-N 2.74Å; D102-T362 PolarHBondContact OD2-OG1 3.14Å; T362-S364 VanDerWaalsContact C-N 3.26Å; T362-S364 PolarHBondContact O-N 3.19Å; T362-I365 PolarHBondContact O-N 3.08Å; T362-Q366 WeakPolarHBondContact O-CG 3.38Å; T362-Q366 PolarHBondContact O-N 3.04Å
363E98.6Very high98.2Very high32 Ų3223 Ų2315%0.1512%0.117CC..Hα-helixtrans-65.6-33178.9-67.9164.2107.600111.4L106 K114 I358 S360 Q366 A367L106-E363 HydrophobicContact CD1-CG 4.19Å; L106-E363 WeakPolarHBondContact CD2-OE2 3.02Å; K114-E363 WeakPolarHBondContact CE-OE2 3.39Å; K114-E363 IonicContact NZ-OE1 2.71Å; K114-E363 PolarHBondContact NZ-OE1 3.12Å; K114-E363 IonicContact NZ-OE2 3.79Å; K114-E363 PolarHBondContact NZ-OE2 3.19Å; I358-E363 HydrophobicContact CB-CB 4.46Å; I358-E363 HydrophobicContact CG1-CB 3.51Å; I358-E363 HydrophobicContact CG1-CG 4.33Å; I358-E363 HydrophobicContact CG2-CB 4.09Å; S360-E363 WeakPolarHBondContact CB-OE2 3.45Å; S360-E363 WeakPolarHBondContact OG-CB 3.27Å; S360-E363 VanDerWaalsContact OG-CG 3.32Å; S360-E363 WeakPolarHBondContact OG-CG 3.37Å; S360-E363 PolarHBondContact OG-N 2.89Å; S360-E363 PolarHBondContact OG-OE2 2.94Å; E363-Q366 PolarHBondContact O-N 3.31Å; E363-A367 WeakPolarHBondContact O-CB 3.48Å; E363-A367 PolarHBondContact O-N 2.96Å
364S98.8Very high98.2Very high0 Ų025 Ų250%013%0.131CC..Hα-helixtrans-63.9-44.8174.1-58.10000112.1L353 V355 I358 S360 V361 T362 Q366 A367 C368L353-S364 WeakPolarHBondContact CD1-O 3.38Å; V355-S364 WeakPolarHBondContact CA-OG 3.18Å; I358-S364 VanDerWaalsContact CG2-OG 3.24Å; I358-S364 WeakPolarHBondContact CG2-OG 3.35Å; S360-S364 WeakPolarHBondContact O-CB 3.42Å; S360-S364 PolarHBondContact O-N 3.01Å; S360-S364 VanDerWaalsContact O-N 3.13Å; S360-S364 PolarHBondContact O-OG 3.49Å; V361-S364 WeakPolarHBondContact O-CB 3.37Å; V361-S364 PolarHBondContact O-N 3.26Å; T362-S364 VanDerWaalsContact C-N 3.26Å; T362-S364 PolarHBondContact O-N 3.19Å; S364-Q366 VanDerWaalsContact C-N 3.3Å; S364-Q366 PolarHBondContact O-N 3Å; S364-A367 PolarHBondContact O-N 3.39Å; S364-C368 PolarHBondContact O-N 2.85Å
365I98.8Very high98.1Very high10 Ų1026.6 Ų26.65%0.05115%0.152CC..Hα-helixtrans-62.4-40.6174.9-66.3167.4000110.2L148 A149 V361 T362 C368 K369 L399L148-I365 HydrophobicContact CB-CD1 3.81Å; L148-I365 HydrophobicContact CD1-CD1 4.3Å; A149-I365 HydrophobicContact CB-CG2 4.14Å; V361-I365 HydrophobicContact CG1-CD1 3.8Å; V361-I365 HydrophobicContact CG1-CG1 4.36Å; V361-I365 WeakPolarHBondContact O-CG1 3.2Å; V361-I365 PolarHBondContact O-N 2.93Å; T362-I365 PolarHBondContact O-N 3.08Å; I365-C368 WeakPolarHBondContact O-CB 3.48Å; I365-C368 PolarHBondContact O-N 3.34Å; I365-K369 HydrophobicContact CG2-CD 4.2Å; I365-K369 WeakPolarHBondContact O-CG 3.19Å; I365-K369 PolarHBondContact O-N 2.86Å; I365-L399 HydrophobicContact CB-CD2 4.4Å; I365-L399 HydrophobicContact CG1-CD2 3.95Å; I365-L399 HydrophobicContact CG2-CD2 4.31Å
366Q98.6Very high98.2Very high90 Ų9027.3 Ų27.342%0.42115%0.154SC..Hα-helixtrans-65.2-43177.7-71.4170.9-600112.2T362 E363 S364 K369 L370T362-Q366 WeakPolarHBondContact O-CG 3.38Å; T362-Q366 PolarHBondContact O-N 3.04Å; E363-Q366 PolarHBondContact O-N 3.31Å; S364-Q366 VanDerWaalsContact C-N 3.3Å; S364-Q366 PolarHBondContact O-N 3Å; Q366-K369 PolarHBondContact O-N 2.72Å; Q366-L370 WeakPolarHBondContact O-CB 3.34Å; Q366-L370 PolarHBondContact O-N 2.89Å
367A98.7Very high98.3Very high0 Ų026.9 Ų26.90%015%0.152CC..Hα-helixtrans-60.3-44.7174.200000111.7T334 I339 L351 E363 S364 L370 A371T334-A367 HydrophobicContact CG2-CB 3.98Å; I339-A367 HydrophobicContact CD1-CB 3.69Å; L351-A367 HydrophobicContact CD2-CB 4.21Å; E363-A367 WeakPolarHBondContact O-CB 3.48Å; E363-A367 PolarHBondContact O-N 2.96Å; S364-A367 PolarHBondContact O-N 3.39Å; A367-L370 PolarHBondContact O-N 3.04Å; A367-A371 PolarHBondContact O-N 3.1Å
368C98.7Very high98.4Very high0 Ų026.8 Ų26.80%015%0.152CC..Hα-helixtrans-57.2-50.4174-174.50000111.9L353 S364 I365 L370 A371 Q372 L399L353-C368 HydrophobicContact CD1-CB 3.61Å; S364-C368 PolarHBondContact O-N 2.85Å; I365-C368 WeakPolarHBondContact O-CB 3.48Å; I365-C368 PolarHBondContact O-N 3.34Å; C368-L370 VanDerWaalsContact C-N 3.35Å; C368-L370 PolarHBondContact O-N 3.39Å; C368-A371 PolarHBondContact O-N 3.3Å; C368-Q372 WeakPolarHBondContact O-CG 3.35Å; C368-Q372 PolarHBondContact O-N 3.01Å; C368-L399 HydrophobicContact CB-CD1 4Å; C368-L399 HydrophobicContact CB-CD2 4.27Å
369K98.1Very high98.4Very high80 Ų8026.4 Ų26.435%0.34815%0.15SC..Hα-helixtrans-60.3-43.1179.1-75.9177.7176.1-178.30112A149 I365 Q366 Q372 T373A149-K369 WeakPolarHBondContact O-CE 3.35Å; A149-K369 PolarHBondContact O-NZ 2.78Å; I365-K369 HydrophobicContact CG2-CD 4.2Å; I365-K369 WeakPolarHBondContact O-CG 3.19Å; I365-K369 PolarHBondContact O-N 2.86Å; Q366-K369 PolarHBondContact O-N 2.72Å; K369-Q372 PolarHBondContact O-N 3.37Å; K369-T373 WeakPolarHBondContact O-CB 3.47Å; K369-T373 VanDerWaalsContact O-CG2 3.25Å; K369-T373 WeakPolarHBondContact O-CG2 3.46Å; K369-T373 PolarHBondContact O-N 3.12Å; K369-T373 PolarHBondContact O-OG1 2.96Å
370L98.4Very high98.5Very high38 Ų3826.4 Ų26.420%0.19915%0.15CC..Hα-helixtrans-60.4-46.2177.5177.760.3000111.3P336 I339 Q366 A367 C368 T373 S374P336-L370 HydrophobicContact CB-CD2 4.16Å; P336-L370 WeakPolarHBondContact O-CD2 3.5Å; I339-L370 HydrophobicContact CB-CD2 3.96Å; I339-L370 HydrophobicContact CG2-CD2 3.67Å; I339-L370 HydrophobicContact CG2-CG 3.85Å; Q366-L370 WeakPolarHBondContact O-CB 3.34Å; Q366-L370 PolarHBondContact O-N 2.89Å; A367-L370 PolarHBondContact O-N 3.04Å; C368-L370 VanDerWaalsContact C-N 3.35Å; C368-L370 PolarHBondContact O-N 3.39Å; L370-T373 PolarHBondContact O-OG1 3.01Å; L370-S374 WeakPolarHBondContact O-CB 3.26Å; L370-S374 PolarHBondContact O-N 3.18Å; L370-S374 VanDerWaalsContact O-N 3.12Å; L370-S374 PolarHBondContact O-OG 2.64Å
371A98.6Very high98.5Very high0 Ų026.5 Ų26.50%015%0.151CC..Hα-helixtrans-61.7-52.6176.100000111.6L351 A367 C368 T373 S374 G375 W376 V378L351-A371 HydrophobicContact CB-CB 3.85Å; L351-A371 HydrophobicContact CD2-CB 4.01Å; A367-A371 PolarHBondContact O-N 3.1Å; C368-A371 PolarHBondContact O-N 3.3Å; A371-T373 PolarHBondContact O-N 3.13Å; A371-S374 CarbonylContact O-C 3.58Å; A371-S374 WeakPolarHBondContact O-CA 3.42Å; A371-S374 WeakPolarHBondContact O-CB 3.34Å; A371-S374 PolarHBondContact O-N 3.5Å; A371-G375 PolarHBondContact O-N 3.45Å; A371-W376 HydrophobicContact CB-CB 4.15Å; A371-W376 HydrophobicContact CB-CE3 4.3Å; A371-W376 WeakPolarHBondContact O-CB 3.45Å; A371-W376 PolarHBondContact O-N 3.15Å; A371-V378 HydrophobicContact CB-CG2 3.68Å
372Q97.8Very high98.5Very high56 Ų5626.7 Ų26.726%0.26215%0.151SC..Hα-helixtrans-60.3-42.9-178.7-72.4176.1-24.300112.8C368 K369 S374 G375 V378 L399C368-Q372 WeakPolarHBondContact O-CG 3.35Å; C368-Q372 PolarHBondContact O-N 3.01Å; K369-Q372 PolarHBondContact O-N 3.37Å; Q372-S374 PolarHBondContact O-N 3.05Å; Q372-G375 PolarHBondContact O-N 2.68Å; Q372-V378 HydrophobicContact CG-CG2 3.96Å; Q372-L399 PolarHBondContact NE2-O 2.98Å; Q372-L399 VanDerWaalsContact NE2-O 3.12Å
373T97.3Very high98.3Very high119 Ų11926.1 Ų26.173%0.7315%0.147SC*.Hα-helixtrans-69.1-21.6177.353.80000113.1K369 L370 A371 G375K369-T373 WeakPolarHBondContact O-CB 3.47Å; K369-T373 VanDerWaalsContact O-CG2 3.25Å; K369-T373 WeakPolarHBondContact O-CG2 3.46Å; K369-T373 PolarHBondContact O-N 3.12Å; K369-T373 PolarHBondContact O-OG1 2.96Å; L370-T373 PolarHBondContact O-OG1 3.01Å; A371-T373 PolarHBondContact O-N 3.13Å; T373-G375 PolarHBondContact O-N 3.05Å
374S97.9Very high98Very high42 Ų4224.8 Ų24.829%0.29414%0.142SC..THydrogen-bonded Turntrans-84.35.6171.5-55.20000113L370 A371 Q372L370-S374 WeakPolarHBondContact O-CB 3.26Å; L370-S374 PolarHBondContact O-N 3.18Å; L370-S374 VanDerWaalsContact O-N 3.12Å; L370-S374 PolarHBondContact O-OG 2.64Å; A371-S374 CarbonylContact O-C 3.58Å; A371-S374 WeakPolarHBondContact O-CA 3.42Å; A371-S374 WeakPolarHBondContact O-CB 3.34Å; A371-S374 PolarHBondContact O-N 3.5Å; Q372-S374 PolarHBondContact O-N 3.05Å
375G97.6Very high97.9Very high47 Ų4724.8 Ų24.849%0.48514%0.142SC..THydrogen-bonded Turntrans76.420.2-17900000113.9A371 Q372 T373 H441A371-G375 PolarHBondContact O-N 3.45Å; Q372-G375 PolarHBondContact O-N 2.68Å; T373-G375 PolarHBondContact O-N 3.05Å; G375-H441 PolarHBondContact O-CE1 3.26Å
376W98.6Very high97.8Very high19 Ų1924.6 Ų24.67%0.07214%0.141CC..  trans-91.9155.2176.8-68.79.3000112.4I339 A342 V343 C348 N349 L351 A371I339-W376 HydrophobicContact CG2-CZ3 4.3Å; A342-W376 HydrophobicContact CB-CH2 3.59Å; A342-W376 HydrophobicContact CB-CZ2 4.4Å; A342-W376 HydrophobicContact CB-CZ3 4.49Å; V343-W376 HydrophobicContact CB-CZ2 4.2Å; V343-W376 HydrophobicContact CG2-CD2 4.27Å; V343-W376 HydrophobicContact CG2-CH2 3.87Å; V343-W376 HydrophobicContact CG2-CZ2 3.5Å; V343-W376 VanDerWaalsContact CG2-CZ2 3.5Å; V343-W376 HydrophobicContact CG2-CZ3 4.41Å; C348-W376 WeakPolarHBondContact O-CZ2 3.47Å; C348-W376 PolarHBondContact O-NE1 3.37Å; C348-W376 WeakPolarHBondContact SG-CH2 3.44Å; C348-W376 WeakPolarHBondContact SG-CZ3 3.4Å; N349-W376 VanDerWaalsContact O-CA 3.27Å; N349-W376 WeakPolarHBondContact O-CA 3.39Å; N349-W376 WeakPolarHBondContact O-CB 3.13Å; L351-W376 HydrophobicContact CB-CE3 4.5Å; A371-W376 HydrophobicContact CB-CB 4.15Å; A371-W376 HydrophobicContact CB-CE3 4.3Å; A371-W376 WeakPolarHBondContact O-CB 3.45Å; A371-W376 PolarHBondContact O-N 3.15Å
377G98.8Very high97.8Very high2 Ų220.5 Ų20.52%0.02112%0.122CC..EExtended strand (participates in β ladder)trans-71.5165160.100000111.6N349 C350 L351 R440N349-G377 PolarHBondContact O-N 2.91Å; C350-G377 VanDerWaalsContact CA-O 3.27Å; C350-G377 WeakPolarHBondContact CA-O 3.22Å; C350-G377 PolarHBondContact SG-O 3.03Å; L351-G377 PolarHBondContact N-O 3.19Å; G377-R440 WeakPolarHBondContact CA-O 3.07Å
378V98.9Very high97.8Very high1 Ų126.4 Ų26.41%0.00615%0.149CC..EExtended strand (participates in β ladder)trans-135.9122.4170.1-178.20000108.5L351 L353 A371 Q372 T401 Q403L351-V378 HydrophobicContact CB-CG1 4.48Å; L351-V378 HydrophobicContact CB-CG2 4.31Å; L351-V378 HydrophobicContact CD2-CG1 4.28Å; L351-V378 HydrophobicContact CG-CG1 4.45Å; L351-V378 CarbonylContact O-C 3.57Å; L351-V378 WeakPolarHBondContact O-CA 3.42Å; L353-V378 HydrophobicContact CB-CG1 3.75Å; L353-V378 HydrophobicContact CD1-CG1 3.88Å; A371-V378 HydrophobicContact CB-CG2 3.68Å; Q372-V378 HydrophobicContact CG-CG2 3.96Å; V378-T401 HydrophobicContact CB-CG2 3.94Å; V378-T401 HydrophobicContact CG1-CG2 3.99Å; V378-T401 WeakPolarHBondContact O-CB 3.39Å; V378-T401 PolarHBondContact O-OG1 3.38Å; V378-Q403 VanDerWaalsContact O-CG 3.25Å; V378-Q403 WeakPolarHBondContact O-CG 3.49Å
379M98.9Very high97.8Very high1 Ų127.3 Ų27.31%0.00515%0.154CC..EExtended strand (participates in β ladder)trans-103.8109.9172.7-176.8-177.2-6100109A160 L351 L352 L353 Q403 K405A160-M379 HydrophobicContact CB-CE 4.49Å; A160-M379 HydrophobicContact CB-SD 4.45Å; L351-M379 PolarHBondContact O-N 2.88Å; L352-M379 WeakPolarHBondContact CA-O 3.5Å; L352-M379 HydrophobicContact CD1-CB 3.96Å; L352-M379 HydrophobicContact CD1-CG 3.94Å; L352-M379 HydrophobicContact CD1-SD 3.88Å; L353-M379 PolarHBondContact N-O 3.28Å; M379-Q403 HydrophobicContact CB-CG 4.05Å; M379-Q403 HydrophobicContact CG-CG 4.41Å; M379-K405 HydrophobicContact CG-CB 4.44Å; M379-K405 HydrophobicContact CG-CG 4.45Å; M379-K405 HydrophobicContact SD-CB 3.76Å; M379-K405 HydrophobicContact SD-CD 3.98Å; M379-K405 HydrophobicContact SD-CG 3.9Å
380V98.9Very high97.9Very high0 Ų025.1 Ų25.10%015%0.147CC..EExtended strand (participates in β ladder)trans-67.1137171.9175.30000108.3I392 L395 V396 L399 T401 Q403 I404 K405V380-I392 HydrophobicContact CG1-CB 3.83Å; V380-I392 HydrophobicContact CG1-CG2 4.29Å; V380-L395 HydrophobicContact CG1-CD2 4.16Å; V380-V396 HydrophobicContact CB-CB 3.84Å; V380-V396 HydrophobicContact CB-CG2 3.99Å; V380-V396 HydrophobicContact CG1-CB 4.26Å; V380-V396 HydrophobicContact CG2-CB 3.75Å; V380-V396 HydrophobicContact CG2-CG2 3.86Å; V380-L399 HydrophobicContact CG2-CD1 4.49Å; V380-T401 HydrophobicContact CG2-CG2 4.03Å; V380-Q403 PolarHBondContact N-O 3.09Å; V380-I404 HydrophobicContact CB-CG1 4.46Å; V380-I404 CarbonylContact O-C 3.46Å; V380-I404 VanDerWaalsContact O-CA 3.29Å; V380-I404 WeakPolarHBondContact O-CA 3.21Å; V380-I404 WeakPolarHBondContact O-CG1 3.26Å; V380-K405 PolarHBondContact O-N 3.46Å
381S98.8Very high97.9Very high3 Ų323.7 Ų23.72%0.02114%0.14CC..EExtended strand (participates in β ladder)trans-129.7144.2-173.2-177.60000112.8L353 K405L353-S381 PolarHBondContact O-N 2.9Å; S381-K405 WeakPolarHBondContact CA-O 3.35Å; S381-K405 VanDerWaalsContact OG-CE 3.24Å; S381-K405 WeakPolarHBondContact OG-CE 3.39Å; S381-K405 WeakPolarHBondContact OG-CG 3.44Å
382H98.2Very high97.9Very high3 Ų324.1 Ų24.11%0.01414%0.142CC..  trans-69.8-173.9159.571.3168.8000112.3E221 E386 I392 K405 T406 G407 R414E221-H382 IonicContact OE1-CE1 3.63Å; E221-H382 IonicContact OE1-NE2 2.71Å; E221-H382 PolarHBondContact OE1-NE2 2.88Å; E221-H382 IonicContact OE2-CE1 2.68Å; E221-H382 PolarHBondContact OE2-CE1 3.01Å; E221-H382 IonicContact OE2-NE2 3.77Å; E221-H382 PolarHBondContact OE2-NE2 2.92Å; H382-E386 HydrophobicContact CB-CG 3.86Å; H382-I392 HydrophobicContact CB-CD1 3.88Å; H382-K405 PolarHBondContact CD2-O 2.8Å; H382-K405 PolarHBondContact N-O 3.3Å; H382-T406 WeakPolarHBondContact ND1-CA 3.22Å; H382-G407 VanDerWaalsContact CE1-CA 3.43Å; H382-G407 WeakPolarHBondContact CE1-CA 3.5Å; H382-G407 PolarHBondContact CE1-N 3.01Å; H382-G407 PolarHBondContact ND1-N 2.69Å; H382-R414 PolarHBondContact ND1-NH1 3.18Å; H382-R414 VanDerWaalsContact ND1-NH1 3.11Å
383R96.2Very high98Very high5 Ų521.4 Ų21.42%0.01913%0.129CC..  trans-120.7164.1159.4-53.3-62.9-66-102.911.8110.4P47 S48 S51 E56 N356 G385 E386 R414P47-R383 HydrophobicContact CB-CB 4.02Å; P47-R383 HydrophobicContact CB-CG 3.85Å; P47-R383 HydrophobicContact CG-CG 3.96Å; S48-R383 WeakPolarHBondContact O-CB 3.26Å; S51-R383 PolarHBondContact O-NH2 3.35Å; E56-R383 IonicContact OE1-CZ 2.97Å; E56-R383 IonicContact OE1-NH1 2.75Å; E56-R383 IonicContact OE1-NH2 2.91Å; E56-R383 PolarHBondContact OE1-NH2 3.11Å; E56-R383 IonicContact OE2-CZ 3.95Å; E56-R383 IonicContact OE2-NH1 3.45Å; E56-R383 PolarHBondContact OE2-NH1 2.99Å; E56-R383 IonicContact OE2-NH2 2.53Å; E56-R383 PolarHBondContact OE2-NH2 3.03Å; N356-R383 PolarHBondContact ND2-NH1 2.95Å; N356-R383 VanDerWaalsContact OD1-CD 3.27Å; N356-R383 WeakPolarHBondContact OD1-CD 3.36Å; N356-R383 WeakPolarHBondContact OD1-CG 3.42Å; N356-R383 PolarHBondContact OD1-NH1 2.62Å; R383-G385 VanDerWaalsContact C-N 3.33Å; R383-G385 PolarHBondContact O-N 2.88Å; R383-E386 WeakPolarHBondContact O-CG 3.37Å; R383-R414 PolarHBondContact O-NH1 3.21Å
384S92.1Very high98.1Very high4 Ų416 Ų163%0.02810%0.096CC..SBendtrans-63.4-33.9176.149.90000113.4S25 A50 H169 E221 R414S25-S384 PolarHBondContact OG-O 2.91Å; A50-S384 VanDerWaalsContact CB-OG 3.22Å; A50-S384 WeakPolarHBondContact CB-OG 3.4Å; A50-S384 PolarHBondContact N-OG 2.62Å; H169-S384 WeakPolarHBondContact NE2-CB 3.28Å; E221-S384 WeakPolarHBondContact OE1-CA 3.45Å; S384-R414 PolarHBondContact O-NH2 2.66Å
385G95.1Very high98.1Very high0 Ų014 Ų140%08%0.082CC..BIsolated β-bridgetrans-91.992.5162.900000111.2P47 S48 R383P47-G385 CarbonylContact C-O 3.58Å; P47-G385 WeakPolarHBondContact CA-O 3.26Å; P47-G385 WeakPolarHBondContact CB-O 3.27Å; S48-G385 PolarHBondContact N-O 2.96Å; S48-G385 CarbonylContact O-C 3.58Å; S48-G385 WeakPolarHBondContact O-CA 3.39Å; S48-G385 PolarHBondContact O-N 3.18Å; R383-G385 VanDerWaalsContact C-N 3.33Å; R383-G385 PolarHBondContact O-N 2.88Å
386E98.3Very high98.2Very high6 Ų611.8 Ų11.83%0.0286%0.059CC..  trans-101.2173.3176.7-105.3-70.3-173.400112.3D24 S25 H382 R383 E413 R414 K417D24-E386 CarbonylContact C-O 3.58Å; D24-E386 WeakPolarHBondContact CA-O 3.28Å; S25-E386 WeakPolarHBondContact CB-O 3.34Å; S25-E386 PolarHBondContact N-O 2.86Å; S25-E386 PolarHBondContact OG-N 3.47Å; S25-E386 PolarHBondContact OG-O 3.28Å; H382-E386 HydrophobicContact CB-CG 3.86Å; R383-E386 WeakPolarHBondContact O-CG 3.37Å; E386-E413 HydrophobicContact CB-CB 3.89Å; E386-E413 HydrophobicContact CB-CG 3.66Å; E386-R414 VanDerWaalsContact CB-NH1 3.33Å; E386-K417 VanDerWaalsContact CD-CE 3.43Å; E386-K417 VanDerWaalsContact OE1-CE 3.23Å; E386-K417 WeakPolarHBondContact OE1-CE 3.22Å; E386-K417 IonicContact OE1-NZ 3.57Å; E386-K417 PolarHBondContact OE1-NZ 3.32Å; E386-K417 WeakPolarHBondContact OE2-CE 3.18Å; E386-K417 IonicContact OE2-NZ 3.76Å; E386-K417 PolarHBondContact OE2-NZ 3.33Å
387T98.8Very high98.2Very high4 Ų410.9 Ų10.93%0.0256%0.056CC..  trans-122.6-178.2175.868.10000109.8I22 T30 A45 D389 E413 K417I22-T387 HydrophobicContact CD1-CG2 4.43Å; T30-T387 HydrophobicContact CG2-CG2 3.89Å; A45-T387 HydrophobicContact CB-CG2 3.9Å; T387-D389 PolarHBondContact O-N 2.83Å; T387-D389 VanDerWaalsContact OG1-CB 3.28Å; T387-D389 WeakPolarHBondContact OG1-CB 3.22Å; T387-D389 PolarHBondContact OG1-N 3.48Å; T387-D389 VanDerWaalsContact OG1-N 3.17Å; T387-E413 WeakPolarHBondContact O-CB 3.43Å; T387-K417 PolarHBondContact O-NZ 2.88Å
388E98.7Very high98.2Very high125 Ų12510.8 Ų10.858%0.5846%0.055SC*.SBendtrans-72.9-8.117066.3-93-125.200113.8
389D98.8Very high98.2Very high18 Ų1810.8 Ų10.810%0.0966%0.055CC..  trans-59.5143.2178.8-160-45.6000110.5A44 A45 K131 T387 F391 K417A44-D389 WeakPolarHBondContact CA-OD2 3.3Å; A45-D389 HydrophobicContact CB-CB 4.35Å; A45-D389 PolarHBondContact N-OD2 3.11Å; K131-D389 IonicContact NZ-OD1 3.67Å; K131-D389 PolarHBondContact NZ-OD1 2.87Å; K131-D389 IonicContact NZ-OD2 3.43Å; K131-D389 PolarHBondContact NZ-OD2 3.25Å; T387-D389 PolarHBondContact O-N 2.83Å; T387-D389 VanDerWaalsContact OG1-CB 3.28Å; T387-D389 WeakPolarHBondContact OG1-CB 3.22Å; T387-D389 PolarHBondContact OG1-N 3.48Å; T387-D389 VanDerWaalsContact OG1-N 3.17Å; D389-F391 WeakPolarHBondContact OD1-CB 3.29Å; D389-F391 PolarHBondContact OD1-N 3.06Å; D389-K417 WeakPolarHBondContact O-CD 3.15Å; D389-K417 WeakPolarHBondContact O-CE 3.17Å; D389-K417 PolarHBondContact O-NZ 3.25Å
390T98.9Very high98.2Very high34 Ų3410.8 Ų10.821%0.2096%0.055CC..  trans-115.412-177.153.30000113.2I392 S393 A416 Q420T390-I392 PolarHBondContact O-N 2.56Å; T390-I392 VanDerWaalsContact O-N 3.08Å; T390-S393 VanDerWaalsContact O-CB 3.27Å; T390-S393 WeakPolarHBondContact O-CB 3.27Å; T390-S393 PolarHBondContact O-N 3.06Å; T390-A416 HydrophobicContact CG2-CB 3.75Å; T390-A416 VanDerWaalsContact CG2-O 3.27Å; T390-A416 WeakPolarHBondContact CG2-O 3.25Å; T390-Q420 HydrophobicContact CG2-CB 4.05Å
391F98.9Very high98.2Very high8 Ų810.9 Ų10.94%0.0356%0.055CC..Hα-helixtrans-49-42.2-174.1-173.5-89.1000114L127 C130 L141 I145 V361 D389 S393 D394 L395L127-F391 HydrophobicContact CB-CD2 4.39Å; L127-F391 HydrophobicContact CB-CE2 4.45Å; L127-F391 HydrophobicContact CD2-CB 4.49Å; L127-F391 HydrophobicContact CD2-CD1 3.41Å; L127-F391 VanDerWaalsContact CD2-CD1 3.41Å; L127-F391 HydrophobicContact CD2-CD2 3.7Å; L127-F391 HydrophobicContact CD2-CE1 3.33Å; L127-F391 HydrophobicContact CD2-CE2 3.64Å; L127-F391 HydrophobicContact CD2-CG 3.6Å; L127-F391 HydrophobicContact CD2-CZ 3.47Å; L127-F391 VanDerWaalsContact CD2-CZ 3.47Å; C130-F391 HydrophobicContact CB-CE2 3.95Å; C130-F391 HydrophobicContact CB-CZ 4.29Å; L141-F391 HydrophobicContact CD1-CE2 4.28Å; L141-F391 HydrophobicContact CD2-CD2 3.78Å; L141-F391 HydrophobicContact CD2-CE2 4.08Å; I145-F391 HydrophobicContact CD1-CE1 4.34Å; I145-F391 HydrophobicContact CD1-CE2 4.23Å; I145-F391 HydrophobicContact CD1-CZ 3.9Å; V361-F391 HydrophobicContact CG1-CZ 4.29Å; V361-F391 HydrophobicContact CG2-CE1 4.2Å; V361-F391 HydrophobicContact CG2-CE2 4.48Å; V361-F391 HydrophobicContact CG2-CZ 3.68Å; D389-F391 WeakPolarHBondContact OD1-CB 3.29Å; D389-F391 PolarHBondContact OD1-N 3.06Å; F391-S393 PolarHBondContact O-N 3.45Å; F391-D394 PolarHBondContact O-N 3.4Å; F391-L395 HydrophobicContact CD1-CB 4.2Å; F391-L395 HydrophobicContact CD1-CD2 4.47Å; F391-L395 HydrophobicContact CE1-CB 4.1Å; F391-L395 HydrophobicContact CE1-CD1 4.01Å; F391-L395 HydrophobicContact CE1-CD2 4.2Å; F391-L395 HydrophobicContact CE1-CG 4.33Å; F391-L395 WeakPolarHBondContact O-CB 3.36Å; F391-L395 PolarHBondContact O-N 3.35Å
392I98.9Very high98.1Very high9 Ų910.8 Ų10.85%0.0465%0.054CC..Hα-helixtrans-66.9-21.5-176.362.9170.2000113.6V380 H382 T390 L395 V396 I404 K417V380-I392 HydrophobicContact CG1-CB 3.83Å; V380-I392 HydrophobicContact CG1-CG2 4.29Å; H382-I392 HydrophobicContact CB-CD1 3.88Å; T390-I392 PolarHBondContact O-N 2.56Å; T390-I392 VanDerWaalsContact O-N 3.08Å; I392-L395 PolarHBondContact O-N 3.24Å; I392-V396 WeakPolarHBondContact O-CG1 3.46Å; I392-V396 PolarHBondContact O-N 3.25Å; I392-I404 HydrophobicContact CD1-CD1 4.35Å; I392-I404 HydrophobicContact CG1-CD1 4.33Å; I392-K417 HydrophobicContact CD1-CG 3.99Å; I392-K417 HydrophobicContact CG1-CG 3.62Å
393S98.9Very high98.2Very high0 Ų010.6 Ų10.60%05%0.054CC..Hα-helixtrans-67.9-45.3172.2-63.70000111.8T390 F391 L395 V396 V397 K417 L421T390-S393 VanDerWaalsContact O-CB 3.27Å; T390-S393 WeakPolarHBondContact O-CB 3.27Å; T390-S393 PolarHBondContact O-N 3.06Å; F391-S393 PolarHBondContact O-N 3.45Å; S393-L395 VanDerWaalsContact C-N 3.33Å; S393-V396 VanDerWaalsContact O-CG1 3.28Å; S393-V396 WeakPolarHBondContact O-CG1 3.35Å; S393-V397 WeakPolarHBondContact O-CG2 3.46Å; S393-V397 PolarHBondContact O-N 2.85Å; S393-K417 WeakPolarHBondContact OG-CA 3.36Å; S393-K417 WeakPolarHBondContact OG-CB 3.17Å; S393-K417 PolarHBondContact OG-O 3.34Å; S393-L421 WeakPolarHBondContact O-CD2 3.29Å
394D98.9Very high98.3Very high6 Ų610.4 Ų10.43%0.0325%0.053CC..Hα-helixtrans-70.6-34.3174.5-75.3-99.6000111.2L141 Y142 I145 F391 G398 Q420L141-D394 HydrophobicContact CB-CB 4.01Å; L141-D394 WeakPolarHBondContact CB-OD1 3.2Å; L141-D394 HydrophobicContact CD2-CB 3.72Å; L141-D394 HydrophobicContact CG-CB 3.69Å; Y142-D394 WeakPolarHBondContact CA-O 3.42Å; Y142-D394 WeakPolarHBondContact CB-O 3.5Å; Y142-D394 PolarHBondContact N-OD1 3.31Å; I145-D394 HydrophobicContact CD1-CB 4.22Å; F391-D394 PolarHBondContact O-N 3.4Å; D394-G398 PolarHBondContact O-N 3.02Å; D394-Q420 PolarHBondContact OD2-NE2 3.02Å
395L98.9Very high98.6Very high0 Ų010.3 Ų10.30%05%0.052CC..Hα-helixtrans-62-50.7177.2-174.267.3000112.2I145 L353 V355 V380 F391 I392 S393 V397 G398 L399I145-L395 HydrophobicContact CD1-CB 4.3Å; I145-L395 HydrophobicContact CD1-CD1 4.25Å; I145-L395 HydrophobicContact CG2-CD1 3.93Å; L353-L395 HydrophobicContact CD2-CD2 3.93Å; V355-L395 HydrophobicContact CG1-CD2 3.38Å; V380-L395 HydrophobicContact CG1-CD2 4.16Å; F391-L395 HydrophobicContact CD1-CB 4.2Å; F391-L395 HydrophobicContact CD1-CD2 4.47Å; F391-L395 HydrophobicContact CE1-CB 4.1Å; F391-L395 HydrophobicContact CE1-CD1 4.01Å; F391-L395 HydrophobicContact CE1-CD2 4.2Å; F391-L395 HydrophobicContact CE1-CG 4.33Å; F391-L395 WeakPolarHBondContact O-CB 3.36Å; F391-L395 PolarHBondContact O-N 3.35Å; I392-L395 PolarHBondContact O-N 3.24Å; S393-L395 VanDerWaalsContact C-N 3.33Å; L395-V397 VanDerWaalsContact C-N 3.29Å; L395-V397 PolarHBondContact O-N 2.88Å; L395-G398 PolarHBondContact O-N 3.06Å; L395-L399 HydrophobicContact CD1-CD1 3.66Å; L395-L399 HydrophobicContact CD1-CG 3.87Å; L395-L399 HydrophobicContact CD2-CD1 4.36Å; L395-L399 HydrophobicContact CG-CD1 3.7Å; L395-L399 HydrophobicContact CG-CG 4.18Å; L395-L399 VanDerWaalsContact O-CB 3.25Å; L395-L399 WeakPolarHBondContact O-CB 3.47Å; L395-L399 VanDerWaalsContact O-CG 3.29Å; L395-L399 WeakPolarHBondContact O-CG 3.26Å; L395-L399 PolarHBondContact O-N 3.35Å
396V98.9Very high98.8Very high0 Ų010.3 Ų10.30%05%0.052CC..Hα-helixtrans-63.4-37.8-177.467.20000112.1P157 V380 I392 S393 C400 T401 Q403 I404 L421P157-V396 HydrophobicContact CB-CG1 4.33Å; P157-V396 HydrophobicContact CB-CG2 3.7Å; P157-V396 HydrophobicContact CG-CG1 3.72Å; P157-V396 HydrophobicContact CG-CG2 4.05Å; V380-V396 HydrophobicContact CB-CB 3.84Å; V380-V396 HydrophobicContact CB-CG2 3.99Å; V380-V396 HydrophobicContact CG1-CB 4.26Å; V380-V396 HydrophobicContact CG2-CB 3.75Å; V380-V396 HydrophobicContact CG2-CG2 3.86Å; I392-V396 WeakPolarHBondContact O-CG1 3.46Å; I392-V396 PolarHBondContact O-N 3.25Å; S393-V396 VanDerWaalsContact O-CG1 3.28Å; S393-V396 WeakPolarHBondContact O-CG1 3.35Å; V396-C400 PolarHBondContact O-N 3.23Å; V396-C400 VanDerWaalsContact O-N 3.14Å; V396-T401 VanDerWaalsContact CG2-OG1 3.28Å; V396-T401 WeakPolarHBondContact CG2-OG1 3.2Å; V396-T401 PolarHBondContact O-N 3.01Å; V396-Q403 WeakPolarHBondContact CG2-O 3.28Å; V396-I404 HydrophobicContact CB-CB 4.41Å; V396-I404 HydrophobicContact CB-CD1 4.41Å; V396-I404 HydrophobicContact CG1-CB 4.27Å; V396-I404 HydrophobicContact CG1-CD1 3.92Å; V396-I404 HydrophobicContact CG2-CB 4.08Å; V396-L421 HydrophobicContact CG1-CD2 3.88Å
397V98.9Very high98.8Very high0 Ų010 Ų100%05%0.05CC..Hα-helixtrans-69-46.11761750000110.4Y142 V154 L156 S393 L395 C400 L421 I424Y142-V397 HydrophobicContact CD2-CG1 4.01Å; Y142-V397 HydrophobicContact CG-CG1 4.14Å; V154-V397 HydrophobicContact CB-CG1 3.75Å; V154-V397 HydrophobicContact CG1-CG1 4.3Å; V154-V397 HydrophobicContact CG2-CG1 4.04Å; L156-V397 HydrophobicContact CD2-CG2 3.99Å; S393-V397 WeakPolarHBondContact O-CG2 3.46Å; S393-V397 PolarHBondContact O-N 2.85Å; L395-V397 VanDerWaalsContact C-N 3.29Å; L395-V397 PolarHBondContact O-N 2.88Å; V397-C400 PolarHBondContact O-N 3.08Å; V397-C400 PolarHBondContact O-SG 2.86Å; V397-L421 HydrophobicContact CG2-CD2 3.61Å; V397-I424 HydrophobicContact CG1-CG2 4.04Å; V397-I424 HydrophobicContact CG2-CD1 4.32Å; V397-I424 HydrophobicContact CG2-CG2 4.17Å
398G98.8Very high98.8Very high0 Ų09.8 Ų9.80%05%0.049CC..Hα-helixtrans-65.4-39.8-179.500000113.5Y142 A146 H151 D394 L395 C400Y142-G398 VanDerWaalsContact O-CA 3.28Å; Y142-G398 WeakPolarHBondContact O-CA 3.35Å; A146-G398 VanDerWaalsContact CA-O 3.28Å; A146-G398 WeakPolarHBondContact CA-O 3.4Å; A146-G398 WeakPolarHBondContact CB-O 3.38Å; H151-G398 PolarHBondContact CD2-O 3.02Å; H151-G398 VanDerWaalsContact CD2-O 3.29Å; D394-G398 PolarHBondContact O-N 3.02Å; L395-G398 PolarHBondContact O-N 3.06Å; G398-C400 PolarHBondContact O-N 3.01Å
399L98.8Very high98.8Very high1 Ų14.6 Ų4.61%0.0053%0.026CC..THydrogen-bonded Turntrans-77.9-6.9175.7-70.5-176000113.8I145 A149 H151 L353 I365 C368 Q372 V380 L395 T401I145-L399 HydrophobicContact CG2-CD2 4.49Å; I145-L399 HydrophobicContact CG2-CG 4.4Å; A149-L399 HydrophobicContact CB-CD2 3.88Å; H151-L399 PolarHBondContact NE2-O 2.85Å; L353-L399 HydrophobicContact CD1-CD1 3.92Å; I365-L399 HydrophobicContact CB-CD2 4.4Å; I365-L399 HydrophobicContact CG1-CD2 3.95Å; I365-L399 HydrophobicContact CG2-CD2 4.31Å; C368-L399 HydrophobicContact CB-CD1 4Å; C368-L399 HydrophobicContact CB-CD2 4.27Å; Q372-L399 PolarHBondContact NE2-O 2.98Å; Q372-L399 VanDerWaalsContact NE2-O 3.12Å; V380-L399 HydrophobicContact CG2-CD1 4.49Å; L395-L399 HydrophobicContact CD1-CD1 3.66Å; L395-L399 HydrophobicContact CD1-CG 3.87Å; L395-L399 HydrophobicContact CD2-CD1 4.36Å; L395-L399 HydrophobicContact CG-CD1 3.7Å; L395-L399 HydrophobicContact CG-CG 4.18Å; L395-L399 VanDerWaalsContact O-CB 3.25Å; L395-L399 WeakPolarHBondContact O-CB 3.47Å; L395-L399 VanDerWaalsContact O-CG 3.29Å; L395-L399 WeakPolarHBondContact O-CG 3.26Å; L395-L399 PolarHBondContact O-N 3.35Å; L399-T401 HydrophobicContact CB-CG2 3.46Å; L399-T401 VanDerWaalsContact CB-CG2 3.46Å; L399-T401 HydrophobicContact CD1-CG2 4.33Å; L399-T401 PolarHBondContact O-N 3.23Å
400C98.6Very high98.8Very high1 Ų15.3 Ų5.31%0.0073%0.032CC..THydrogen-bonded Turntrans53.237.9179.1-57.10000114.3D153 I155 V396 V397 G398 I444D153-C400 PolarHBondContact O-SG 3.19Å; I155-C400 VanDerWaalsContact CG2-CA 3.49Å; I155-C400 HydrophobicContact CG2-CB 3.7Å; V396-C400 PolarHBondContact O-N 3.23Å; V396-C400 VanDerWaalsContact O-N 3.14Å; V397-C400 PolarHBondContact O-N 3.08Å; V397-C400 PolarHBondContact O-SG 2.86Å; G398-C400 PolarHBondContact O-N 3.01Å; C400-I444 HydrophobicContact CB-CD1 3.36Å; C400-I444 HydrophobicContact CB-CG1 4.06Å
401T98.8Very high98.8Very high2 Ų27.5 Ų7.51%0.0124%0.037CC..  trans-81-20.4-170.984.20000113.5V378 V380 V396 L399 Q403V378-T401 HydrophobicContact CB-CG2 3.94Å; V378-T401 HydrophobicContact CG1-CG2 3.99Å; V378-T401 WeakPolarHBondContact O-CB 3.39Å; V378-T401 PolarHBondContact O-OG1 3.38Å; V380-T401 HydrophobicContact CG2-CG2 4.03Å; V396-T401 VanDerWaalsContact CG2-OG1 3.28Å; V396-T401 WeakPolarHBondContact CG2-OG1 3.2Å; V396-T401 PolarHBondContact O-N 3.01Å; L399-T401 HydrophobicContact CB-CG2 3.46Å; L399-T401 VanDerWaalsContact CB-CG2 3.46Å; L399-T401 HydrophobicContact CD1-CG2 4.33Å; L399-T401 PolarHBondContact O-N 3.23Å; T401-Q403 VanDerWaalsContact C-N 3.29Å; T401-Q403 PolarHBondContact O-N 2.82Å; T401-Q403 PolarHBondContact OG1-O 3.46Å
402G98.7Very high98.7Very high0 Ų011.6 Ų11.60%07%0.066CC..SBendtrans78.42.5174.100000116.1P157 V158 A435 P442P157-G402 CarbonylContact C-O 3.56Å; P157-G402 VanDerWaalsContact CA-C 3.4Å; P157-G402 VanDerWaalsContact CA-O 3.31Å; P157-G402 WeakPolarHBondContact CA-O 3.35Å; V158-G402 PolarHBondContact N-O 3.24Å; G402-A435 WeakPolarHBondContact O-CB 3.42Å; G402-P442 VanDerWaalsContact CA-CG 3.46Å
403Q98.9Very high98.7Very high0 Ų012.1 Ų12.10%07%0.069CC..EExtended strand (participates in β ladder)trans-154.9140.3178.547.2-179.5-51.400111.6V158 V378 M379 V380 V396 T401 F439V158-Q403 WeakPolarHBondContact O-CA 3.48Å; V378-Q403 VanDerWaalsContact O-CG 3.25Å; V378-Q403 WeakPolarHBondContact O-CG 3.49Å; M379-Q403 HydrophobicContact CB-CG 4.05Å; M379-Q403 HydrophobicContact CG-CG 4.41Å; V380-Q403 PolarHBondContact N-O 3.09Å; V396-Q403 WeakPolarHBondContact CG2-O 3.28Å; T401-Q403 VanDerWaalsContact C-N 3.29Å; T401-Q403 PolarHBondContact O-N 2.82Å; T401-Q403 PolarHBondContact OG1-O 3.46Å; Q403-F439 HydrophobicContact CB-CB 4.43Å; Q403-F439 HydrophobicContact CB-CD2 4.04Å; Q403-F439 VanDerWaalsContact CD-CD2 3.49Å; Q403-F439 HydrophobicContact CG-CD2 4.23Å; Q403-F439 PolarHBondContact NE2-O 3.2Å
404I98.9Very high98.7Very high0 Ų012.1 Ų12.10%07%0.069CC..EExtended strand (participates in β ladder)trans-138.5134.5178.9-174.7170.3000109.9P157 V158 P159 A160 V380 I392 V396 T406 L421P157-I404 HydrophobicContact CB-CB 4.24Å; P157-I404 HydrophobicContact CB-CG2 3.84Å; P157-I404 HydrophobicContact CG-CB 4.23Å; P157-I404 HydrophobicContact CG-CG2 3.53Å; V158-I404 PolarHBondContact O-N 2.86Å; V158-I404 VanDerWaalsContact O-N 3.09Å; P159-I404 CarbonylContact C-O 3.59Å; P159-I404 WeakPolarHBondContact CA-O 3.11Å; A160-I404 PolarHBondContact N-O 3.21Å; V380-I404 HydrophobicContact CB-CG1 4.46Å; V380-I404 CarbonylContact O-C 3.46Å; V380-I404 VanDerWaalsContact O-CA 3.29Å; V380-I404 WeakPolarHBondContact O-CA 3.21Å; V380-I404 WeakPolarHBondContact O-CG1 3.26Å; I392-I404 HydrophobicContact CD1-CD1 4.35Å; I392-I404 HydrophobicContact CG1-CD1 4.33Å; V396-I404 HydrophobicContact CB-CB 4.41Å; V396-I404 HydrophobicContact CB-CD1 4.41Å; V396-I404 HydrophobicContact CG1-CB 4.27Å; V396-I404 HydrophobicContact CG1-CD1 3.92Å; V396-I404 HydrophobicContact CG2-CB 4.08Å; I404-T406 HydrophobicContact CD1-CG2 3.91Å; I404-T406 HydrophobicContact CG1-CG2 4.11Å; I404-L421 HydrophobicContact CD1-CD1 4.25Å; I404-L421 HydrophobicContact CG2-CD1 3.96Å
405K98.8Very high98.7Very high2 Ų214.1 Ų14.11%0.0098%0.079CC..EExtended strand (participates in β ladder)trans-106.2117.9160.776.9174.7-166.3171.60109.7A160 E178 M180 D256 E304 L352 M379 V380 S381 H382A160-K405 HydrophobicContact CB-CB 3.98Å; E178-K405 IonicContact OE1-NZ 3.48Å; E178-K405 IonicContact OE2-NZ 3.8Å; E178-K405 PolarHBondContact OE2-NZ 2.95Å; M180-K405 HydrophobicContact CE-CD 4.4Å; M180-K405 HydrophobicContact SD-CB 4.13Å; M180-K405 HydrophobicContact SD-CD 4.02Å; D256-K405 IonicContact OD2-NZ 2.95Å; E304-K405 IonicContact OE1-NZ 3.3Å; E304-K405 PolarHBondContact OE1-NZ 2.62Å; E304-K405 WeakPolarHBondContact OE2-CE 3.36Å; E304-K405 IonicContact OE2-NZ 3.39Å; E304-K405 PolarHBondContact OE2-NZ 3.34Å; L352-K405 HydrophobicContact CD1-CD 3.93Å; L352-K405 HydrophobicContact CD1-CG 4.2Å; M379-K405 HydrophobicContact CG-CB 4.44Å; M379-K405 HydrophobicContact CG-CG 4.45Å; M379-K405 HydrophobicContact SD-CB 3.76Å; M379-K405 HydrophobicContact SD-CD 3.98Å; M379-K405 HydrophobicContact SD-CG 3.9Å; V380-K405 PolarHBondContact O-N 3.46Å; S381-K405 WeakPolarHBondContact CA-O 3.35Å; S381-K405 VanDerWaalsContact OG-CE 3.24Å; S381-K405 WeakPolarHBondContact OG-CE 3.39Å; S381-K405 WeakPolarHBondContact OG-CG 3.44Å; H382-K405 PolarHBondContact CD2-O 2.8Å; H382-K405 PolarHBondContact N-O 3.3Å
406T98.7Very high98.7Very high0 Ų015.1 Ų15.10%09%0.087CC..  trans-139.333.4178.7-174.80000112.8H382 I404 R414 K417 Y418H382-T406 WeakPolarHBondContact ND1-CA 3.22Å; I404-T406 HydrophobicContact CD1-CG2 3.91Å; I404-T406 HydrophobicContact CG1-CG2 4.11Å; T406-R414 WeakPolarHBondContact O-CA 3.38Å; T406-R414 WeakPolarHBondContact O-CB 3.45Å; T406-R414 WeakPolarHBondContact O-CD 3.49Å; T406-K417 HydrophobicContact CG2-CB 3.73Å; T406-K417 HydrophobicContact CG2-CG 4.48Å; T406-Y418 HydrophobicContact CG2-CD1 3.69Å; T406-Y418 HydrophobicContact CG2-CD2 4.21Å; T406-Y418 HydrophobicContact CG2-CE1 3.2Å; T406-Y418 HydrophobicContact CG2-CE2 3.77Å; T406-Y418 HydrophobicContact CG2-CG 4.17Å; T406-Y418 PolarHBondContact N-OH 3.22Å
407G98.3Very high98.7Very high0 Ų015.1 Ų15.10%09%0.087CC..  trans93.1-174.3172.700000114.4F161 H382 Y418F161-G407 WeakPolarHBondContact CA-O 3.11Å; H382-G407 VanDerWaalsContact CE1-CA 3.43Å; H382-G407 WeakPolarHBondContact CE1-CA 3.5Å; H382-G407 PolarHBondContact CE1-N 3.01Å; H382-G407 PolarHBondContact ND1-N 2.69Å; G407-Y418 PolarHBondContact N-OH 3.03Å; G407-Y418 VanDerWaalsContact O-CE2 3.3Å; G407-Y418 WeakPolarHBondContact O-CE2 3.45Å; G407-Y418 PolarHBondContact O-OH 3.34Å
408A98.7Very high98.7Very high0 Ų015.1 Ų15.10%09%0.087CC..  trans-63.7164.2174.500000111.7N162 Y200 E221 G222 C410 R414N162-A408 WeakPolarHBondContact O-CA 3.49Å; N162-A408 WeakPolarHBondContact O-CB 3.17Å; N162-A408 PolarHBondContact O-N 2.79Å; Y200-A408 HydrophobicContact CD2-CB 4.45Å; Y200-A408 HydrophobicContact CE2-CB 4.01Å; E221-A408 WeakPolarHBondContact O-CB 3.15Å; E221-A408 PolarHBondContact O-N 3.18Å; G222-A408 WeakPolarHBondContact O-CB 3.35Å; A408-C410 HydrophobicContact CB-CB 3.96Å; A408-C410 PolarHBondContact O-N 3.02Å; A408-R414 WeakPolarHBondContact O-CB 3.29Å
409P98.6Very high98.7Very high16 Ų1617.9 Ų17.910%0.10410%0.102CC..SBendtrans-7247.4160.334-36.4000111.2F161 A197 Y200 L415F161-P409 HydrophobicContact CD1-CB 4.44Å; F161-P409 HydrophobicContact CD1-CG 4.44Å; F161-P409 HydrophobicContact CE1-CB 4.49Å; A197-P409 HydrophobicContact CB-CB 4.27Å; A197-P409 HydrophobicContact CB-CG 4.49Å; Y200-P409 HydrophobicContact CD1-CG 4.12Å; Y200-P409 HydrophobicContact CD2-CG 4.33Å; Y200-P409 HydrophobicContact CG-CG 3.78Å; P409-L415 HydrophobicContact CB-CD2 4.39Å
410C98.5Very high98.7Very high32 Ų3219.6 Ų19.622%0.21611%0.11CC..  trans-150.4150-178.3-173.80000109Y200 A408 R414Y200-C410 HydrophobicContact CE1-CB 3.94Å; Y200-C410 WeakPolarHBondContact OH-CB 3.2Å; Y200-C410 PolarHBondContact OH-SG 3.18Å; A408-C410 HydrophobicContact CB-CB 3.96Å; A408-C410 PolarHBondContact O-N 3.02Å; C410-R414 WeakPolarHBondContact O-CB 3.19Å; C410-R414 VanDerWaalsContact O-CG 3.26Å; C410-R414 WeakPolarHBondContact O-CG 3.2Å
411R98.3Very high98.8Very high81 Ų8119.5 Ų19.531%0.30611%0.109SC..SBendtrans66.6132.8-173.4-48.4174.6511017.5113.2S25 V218 D220 E413 R414 L415S25-R411 PolarHBondContact O-NH2 3.03Å; V218-R411 HydrophobicContact CG2-CG 4.47Å; D220-R411 PolarHBondContact O-NE 3.29Å; R411-E413 WeakPolarHBondContact CB-OE1 3.42Å; R411-E413 WeakPolarHBondContact CB-OE2 3.37Å; R411-E413 IonicContact CZ-OE1 2.64Å; R411-E413 IonicContact NE-OE1 3.15Å; R411-E413 PolarHBondContact NE-OE1 3.42Å; R411-E413 IonicContact NE-OE2 2.9Å; R411-E413 IonicContact NH2-OE1 3.89Å; R411-E413 PolarHBondContact NH2-OE1 2.94Å; R411-E413 PolarHBondContact O-N 3.45Å; R411-R414 HydrophobicContact CB-CG 4.28Å; R411-R414 WeakPolarHBondContact O-CB 3.4Å; R411-R414 PolarHBondContact O-N 3.01Å; R411-R414 VanDerWaalsContact O-N 3.08Å; R411-L415 PolarHBondContact O-N 3.21Å
412S98.8Very high98.8Very high93 Ų9321.4 Ų21.465%0.6512%0.118SC*.Hα-helixtrans-73.9-24.3-164.2-64.70000114R414 L415 A416S412-R414 PolarHBondContact O-N 3.22Å; S412-L415 PolarHBondContact O-N 3.36Å; S412-A416 WeakPolarHBondContact O-CA 3.49Å; S412-A416 WeakPolarHBondContact O-CB 3.4Å; S412-A416 PolarHBondContact O-N 2.82Å
413E98.6Very high98.8Very high21 Ų2127.7 Ų27.710%0.09814%0.142CC..Hα-helixtrans-64-20.8171.878.1-79.1-172.300112.1S25 E386 T387 R411 K417S25-E413 VanDerWaalsContact CB-CG 3.48Å; E386-E413 HydrophobicContact CB-CB 3.89Å; E386-E413 HydrophobicContact CB-CG 3.66Å; T387-E413 WeakPolarHBondContact O-CB 3.43Å; R411-E413 WeakPolarHBondContact CB-OE1 3.42Å; R411-E413 WeakPolarHBondContact CB-OE2 3.37Å; R411-E413 IonicContact CZ-OE1 2.64Å; R411-E413 IonicContact NE-OE1 3.15Å; R411-E413 PolarHBondContact NE-OE1 3.42Å; R411-E413 IonicContact NE-OE2 2.9Å; R411-E413 IonicContact NH2-OE1 3.89Å; R411-E413 PolarHBondContact NH2-OE1 2.94Å; R411-E413 PolarHBondContact O-N 3.45Å; E413-K417 VanDerWaalsContact O-CD 3.23Å; E413-K417 WeakPolarHBondContact O-CD 3.32Å; E413-K417 WeakPolarHBondContact O-CE 3.34Å; E413-K417 PolarHBondContact O-NZ 3.08Å
414R98.7Very high98.8Very high0 Ų027.7 Ų27.70%014%0.142CC..Hα-helixtrans-89.5-54.9174.1-43.4-52.4166.1-1794.6110D220 H382 R383 S384 E386 T406 A408 C410 R411 S412 A416 K417 Y418D220-R414 PolarHBondContact O-NH2 3.25Å; H382-R414 PolarHBondContact ND1-NH1 3.18Å; H382-R414 VanDerWaalsContact ND1-NH1 3.11Å; R383-R414 PolarHBondContact O-NH1 3.21Å; S384-R414 PolarHBondContact O-NH2 2.66Å; E386-R414 VanDerWaalsContact CB-NH1 3.33Å; T406-R414 WeakPolarHBondContact O-CA 3.38Å; T406-R414 WeakPolarHBondContact O-CB 3.45Å; T406-R414 WeakPolarHBondContact O-CD 3.49Å; A408-R414 WeakPolarHBondContact O-CB 3.29Å; C410-R414 WeakPolarHBondContact O-CB 3.19Å; C410-R414 VanDerWaalsContact O-CG 3.26Å; C410-R414 WeakPolarHBondContact O-CG 3.2Å; R411-R414 HydrophobicContact CB-CG 4.28Å; R411-R414 WeakPolarHBondContact O-CB 3.4Å; R411-R414 PolarHBondContact O-N 3.01Å; R411-R414 VanDerWaalsContact O-N 3.08Å; S412-R414 PolarHBondContact O-N 3.22Å; R414-A416 PolarHBondContact O-N 3.09Å; R414-K417 PolarHBondContact O-N 3.18Å; R414-Y418 HydrophobicContact CB-CE2 4.5Å; R414-Y418 WeakPolarHBondContact O-CD2 3.31Å; R414-Y418 PolarHBondContact O-N 3.36Å
415L98.9Very high98.8Very high47 Ų4728.7 Ų28.725%0.24615%0.147CC..Hα-helixtrans-60.7-27.7-179.8-68.4172.2000112.7P409 R411 S412 K417 Y418 N419P409-L415 HydrophobicContact CB-CD2 4.39Å; R411-L415 PolarHBondContact O-N 3.21Å; S412-L415 PolarHBondContact O-N 3.36Å; L415-K417 PolarHBondContact O-N 3.06Å; L415-Y418 PolarHBondContact O-N 3.38Å; L415-N419 WeakPolarHBondContact O-CB 3.48Å; L415-N419 PolarHBondContact O-N 3.35Å; L415-N419 PolarHBondContact O-ND2 2.5Å
416A98.9Very high98.8Very high21 Ų2136 Ų3617%0.17418%0.181CC..Hα-helixtrans-55.1-43.4174.200000111.2T390 S412 R414 Q420T390-A416 HydrophobicContact CG2-CB 3.75Å; T390-A416 VanDerWaalsContact CG2-O 3.27Å; T390-A416 WeakPolarHBondContact CG2-O 3.25Å; S412-A416 WeakPolarHBondContact O-CA 3.49Å; S412-A416 WeakPolarHBondContact O-CB 3.4Å; S412-A416 PolarHBondContact O-N 2.82Å; R414-A416 PolarHBondContact O-N 3.09Å; A416-Q420 WeakPolarHBondContact O-CB 3.37Å; A416-Q420 PolarHBondContact O-N 2.73Å
417K98.9Very high98.8Very high1 Ų141.6 Ų41.60%0.00421%0.207CC..Hα-helixtrans-71.8-46.2-179.9-75.566.2159.5175.20111.4E386 T387 D389 I392 S393 T406 E413 R414 L415 N419 Q420 L421E386-K417 VanDerWaalsContact CD-CE 3.43Å; E386-K417 VanDerWaalsContact OE1-CE 3.23Å; E386-K417 WeakPolarHBondContact OE1-CE 3.22Å; E386-K417 IonicContact OE1-NZ 3.57Å; E386-K417 PolarHBondContact OE1-NZ 3.32Å; E386-K417 WeakPolarHBondContact OE2-CE 3.18Å; E386-K417 IonicContact OE2-NZ 3.76Å; E386-K417 PolarHBondContact OE2-NZ 3.33Å; T387-K417 PolarHBondContact O-NZ 2.88Å; D389-K417 WeakPolarHBondContact O-CD 3.15Å; D389-K417 WeakPolarHBondContact O-CE 3.17Å; D389-K417 PolarHBondContact O-NZ 3.25Å; I392-K417 HydrophobicContact CD1-CG 3.99Å; I392-K417 HydrophobicContact CG1-CG 3.62Å; S393-K417 WeakPolarHBondContact OG-CA 3.36Å; S393-K417 WeakPolarHBondContact OG-CB 3.17Å; S393-K417 PolarHBondContact OG-O 3.34Å; T406-K417 HydrophobicContact CG2-CB 3.73Å; T406-K417 HydrophobicContact CG2-CG 4.48Å; E413-K417 VanDerWaalsContact O-CD 3.23Å; E413-K417 WeakPolarHBondContact O-CD 3.32Å; E413-K417 WeakPolarHBondContact O-CE 3.34Å; E413-K417 PolarHBondContact O-NZ 3.08Å; R414-K417 PolarHBondContact O-N 3.18Å; L415-K417 PolarHBondContact O-N 3.06Å; K417-N419 PolarHBondContact O-N 3.1Å; K417-Q420 WeakPolarHBondContact O-CB 3.22Å; K417-Q420 PolarHBondContact O-N 2.88Å; K417-Q420 VanDerWaalsContact O-N 3.16Å; K417-L421 WeakPolarHBondContact O-CG 3.37Å; K417-L421 PolarHBondContact O-N 3.08Å
418Y98.9Very high98.8Very high0 Ų042.8 Ų42.80%021%0.213CC..Hα-helixtrans-62.8-42177.9-68.2-48.8000112.4P159 A160 F161 F189 M193 T406 G407 R414 L415 Q420 L421 M422P159-Y418 HydrophobicContact CB-CD1 4.24Å; P159-Y418 HydrophobicContact CB-CE1 3.63Å; A160-Y418 PolarHBondContact O-OH 2.65Å; F161-Y418 HydrophobicContact CD1-CE1 4.07Å; F161-Y418 AromaticContact CD1-CE2 3.74Å; F161-Y418 HydrophobicContact CD1-CE2 3.74Å; F161-Y418 AromaticContact CD1-CZ 3.47Å; F161-Y418 VanDerWaalsContact CD1-CZ 3.47Å; F161-Y418 WeakPolarHBondContact CD1-OH 3.34Å; F161-Y418 HydrophobicContact CE1-CD1 4.02Å; F161-Y418 HydrophobicContact CE1-CD2 4.12Å; F161-Y418 AromaticContact CE1-CE1 3.62Å; F161-Y418 HydrophobicContact CE1-CE1 3.62Å; F161-Y418 AromaticContact CE1-CE2 3.73Å; F161-Y418 HydrophobicContact CE1-CE2 3.73Å; F161-Y418 HydrophobicContact CE1-CG 4.26Å; F161-Y418 AromaticContact CE1-CZ 3.46Å; F161-Y418 VanDerWaalsContact CE1-CZ 3.46Å; F161-Y418 HydrophobicContact CZ-CE1 4.45Å; F189-Y418 WeakPolarHBondContact CE1-O 3.46Å; F189-Y418 HydrophobicContact CZ-CD1 4.08Å; M193-Y418 HydrophobicContact CE-CD1 4.3Å; M193-Y418 HydrophobicContact CE-CD2 4.1Å; M193-Y418 HydrophobicContact CE-CG 3.73Å; M193-Y418 VanDerWaalsContact SD-CB 3.57Å; M193-Y418 HydrophobicContact SD-CD1 3.59Å; M193-Y418 VanDerWaalsContact SD-CD1 3.59Å; M193-Y418 HydrophobicContact SD-CD2 4.45Å; M193-Y418 HydrophobicContact SD-CE1 4.38Å; M193-Y418 HydrophobicContact SD-CG 3.62Å; T406-Y418 HydrophobicContact CG2-CD1 3.69Å; T406-Y418 HydrophobicContact CG2-CD2 4.21Å; T406-Y418 HydrophobicContact CG2-CE1 3.2Å; T406-Y418 HydrophobicContact CG2-CE2 3.77Å; T406-Y418 HydrophobicContact CG2-CG 4.17Å; T406-Y418 PolarHBondContact N-OH 3.22Å; G407-Y418 PolarHBondContact N-OH 3.03Å; G407-Y418 VanDerWaalsContact O-CE2 3.3Å; G407-Y418 WeakPolarHBondContact O-CE2 3.45Å; G407-Y418 PolarHBondContact O-OH 3.34Å; R414-Y418 HydrophobicContact CB-CE2 4.5Å; R414-Y418 WeakPolarHBondContact O-CD2 3.31Å; R414-Y418 PolarHBondContact O-N 3.36Å; L415-Y418 PolarHBondContact O-N 3.38Å; Y418-Q420 VanDerWaalsContact C-N 3.3Å; Y418-Q420 PolarHBondContact O-N 3.05Å; Y418-L421 HydrophobicContact CD1-CD1 4.49Å; Y418-L421 PolarHBondContact O-N 3.32Å; Y418-M422 PolarHBondContact O-N 3.44Å
419N98.9Very high98.7Very high57 Ų5744.7 Ų44.731%0.30523%0.233SC..Hα-helixtrans-65.1-35.7174.4-68.6-22.3000111.5L415 K417 M422 R423L415-N419 WeakPolarHBondContact O-CB 3.48Å; L415-N419 PolarHBondContact O-N 3.35Å; L415-N419 PolarHBondContact O-ND2 2.5Å; K417-N419 PolarHBondContact O-N 3.1Å; N419-M422 HydrophobicContact CB-CE 4.34Å; N419-M422 PolarHBondContact O-N 2.86Å; N419-M422 WeakPolarHBondContact OD1-CE 3.23Å; N419-R423 WeakPolarHBondContact O-CG 3.24Å; N419-R423 PolarHBondContact O-N 3.18Å
420Q98.9Very high98.6Very high37 Ų3752.5 Ų52.517%0.17327%0.274CS..Hα-helixtrans-64.5-40.3173.5-179.761.3700112T390 D394 A416 K417 Y418 M422 R423 I424T390-Q420 HydrophobicContact CG2-CB 4.05Å; D394-Q420 PolarHBondContact OD2-NE2 3.02Å; A416-Q420 WeakPolarHBondContact O-CB 3.37Å; A416-Q420 PolarHBondContact O-N 2.73Å; K417-Q420 WeakPolarHBondContact O-CB 3.22Å; K417-Q420 PolarHBondContact O-N 2.88Å; K417-Q420 VanDerWaalsContact O-N 3.16Å; Y418-Q420 VanDerWaalsContact C-N 3.3Å; Y418-Q420 PolarHBondContact O-N 3.05Å; Q420-M422 VanDerWaalsContact C-N 3.34Å; Q420-M422 PolarHBondContact O-N 2.8Å; Q420-R423 WeakPolarHBondContact O-CB 3.49Å; Q420-R423 PolarHBondContact O-N 2.92Å; Q420-R423 VanDerWaalsContact O-N 3.14Å; Q420-R423 VanDerWaalsContact OE1-NH1 3.11Å; Q420-I424 HydrophobicContact CG-CD1 4.06Å; Q420-I424 WeakPolarHBondContact O-CG1 3.2Å; Q420-I424 PolarHBondContact O-N 3.03Å
421L98.9Very high98.5Very high0 Ų059.1 Ų59.10%030%0.299CS..Hα-helixtrans-64.1-38175.1-71.8166.5000112.5L156 P157 F189 S393 V396 V397 I404 K417 Y418 R423 I424 E425L156-L421 HydrophobicContact CD2-CD2 4.39Å; P157-L421 HydrophobicContact CG-CD1 4Å; P157-L421 HydrophobicContact CG-CD2 4.01Å; F189-L421 HydrophobicContact CD1-CB 3.81Å; F189-L421 HydrophobicContact CD2-CB 4.39Å; F189-L421 HydrophobicContact CE1-CB 3.26Å; F189-L421 HydrophobicContact CE1-CD1 4.26Å; F189-L421 HydrophobicContact CE1-CG 4.38Å; F189-L421 HydrophobicContact CE2-CB 3.91Å; F189-L421 HydrophobicContact CE2-CD1 3.63Å; F189-L421 HydrophobicContact CE2-CG 4.32Å; F189-L421 HydrophobicContact CG-CB 4.35Å; F189-L421 HydrophobicContact CZ-CB 3.32Å; F189-L421 HydrophobicContact CZ-CD1 3.41Å; F189-L421 VanDerWaalsContact CZ-CD1 3.41Å; F189-L421 HydrophobicContact CZ-CG 3.98Å; S393-L421 WeakPolarHBondContact O-CD2 3.29Å; V396-L421 HydrophobicContact CG1-CD2 3.88Å; V397-L421 HydrophobicContact CG2-CD2 3.61Å; I404-L421 HydrophobicContact CD1-CD1 4.25Å; I404-L421 HydrophobicContact CG2-CD1 3.96Å; K417-L421 WeakPolarHBondContact O-CG 3.37Å; K417-L421 PolarHBondContact O-N 3.08Å; Y418-L421 HydrophobicContact CD1-CD1 4.49Å; Y418-L421 PolarHBondContact O-N 3.32Å; L421-R423 VanDerWaalsContact C-N 3.33Å; L421-R423 PolarHBondContact O-N 3.2Å; L421-I424 HydrophobicContact CD2-CD1 4.49Å; L421-I424 PolarHBondContact O-N 3.04Å; L421-E425 WeakPolarHBondContact O-CB 3.45Å; L421-E425 PolarHBondContact O-N 3.05Å
422M98.9Very high98.5Very high41 Ų4156.8 Ų56.820%0.20230%0.297CS..Hα-helixtrans-61.2-39.7171.2-75.2-167.6-63.600112.2F189 H190 M193 Y418 N419 Q420 E425 E426F189-M422 HydrophobicContact CD1-CG 3.8Å; F189-M422 HydrophobicContact CE1-CG 3.83Å; H190-M422 WeakPolarHBondContact CE1-CB 3.36Å; H190-M422 PolarHBondContact CE1-O 2.89Å; M193-M422 HydrophobicContact CB-SD 4.17Å; M193-M422 HydrophobicContact CG-CG 4.13Å; M193-M422 HydrophobicContact CG-SD 4.1Å; Y418-M422 PolarHBondContact O-N 3.44Å; N419-M422 HydrophobicContact CB-CE 4.34Å; N419-M422 PolarHBondContact O-N 2.86Å; N419-M422 WeakPolarHBondContact OD1-CE 3.23Å; Q420-M422 VanDerWaalsContact C-N 3.34Å; Q420-M422 PolarHBondContact O-N 2.8Å; M422-E425 PolarHBondContact O-N 2.77Å; M422-E426 PolarHBondContact O-N 3.18Å
423R98.9Very high98.4Very high132 Ų13256.1 Ų56.150%0.49828%0.282SS..Hα-helixtrans-67.7-41175-67179-155.8108.93.6112.5N419 Q420 L421 E425 E426 E427N419-R423 WeakPolarHBondContact O-CG 3.24Å; N419-R423 PolarHBondContact O-N 3.18Å; Q420-R423 WeakPolarHBondContact O-CB 3.49Å; Q420-R423 PolarHBondContact O-N 2.92Å; Q420-R423 VanDerWaalsContact O-N 3.14Å; Q420-R423 VanDerWaalsContact OE1-NH1 3.11Å; L421-R423 VanDerWaalsContact C-N 3.33Å; L421-R423 PolarHBondContact O-N 3.2Å; R423-E425 VanDerWaalsContact C-N 3.3Å; R423-E425 PolarHBondContact O-N 3.18Å; R423-E426 PolarHBondContact O-N 2.88Å; R423-E427 WeakPolarHBondContact O-CB 3.36Å; R423-E427 PolarHBondContact O-N 2.87Å
424I98.9Very high98.4Very high1 Ų156.6 Ų56.61%0.00528%0.284CS..Hα-helixtrans-63-41176.2-67.1165.8000110.2Y142 L156 V397 Q420 L421 E427 L428Y142-I424 HydrophobicContact CD1-CB 4.44Å; Y142-I424 HydrophobicContact CD1-CD1 4.16Å; Y142-I424 HydrophobicContact CD1-CG1 3.85Å; Y142-I424 HydrophobicContact CD1-CG2 3.82Å; Y142-I424 HydrophobicContact CE1-CG1 4.21Å; Y142-I424 HydrophobicContact CE1-CG2 3.89Å; Y142-I424 HydrophobicContact CG-CG2 4.17Å; L156-I424 HydrophobicContact CD2-CG2 4.37Å; V397-I424 HydrophobicContact CG1-CG2 4.04Å; V397-I424 HydrophobicContact CG2-CD1 4.32Å; V397-I424 HydrophobicContact CG2-CG2 4.17Å; Q420-I424 HydrophobicContact CG-CD1 4.06Å; Q420-I424 WeakPolarHBondContact O-CG1 3.2Å; Q420-I424 PolarHBondContact O-N 3.03Å; L421-I424 HydrophobicContact CD2-CD1 4.49Å; L421-I424 PolarHBondContact O-N 3.04Å; I424-E427 PolarHBondContact O-N 2.84Å; I424-L428 HydrophobicContact CG2-CD1 3.86Å; I424-L428 HydrophobicContact CG2-CG 4.35Å; I424-L428 WeakPolarHBondContact O-CB 3.21Å; I424-L428 VanDerWaalsContact O-CG 3.26Å; I424-L428 WeakPolarHBondContact O-CG 3.28Å; I424-L428 PolarHBondContact O-N 2.91Å
425E98.8Very high98.4Very high21 Ų2156.9 Ų56.910%0.09829%0.287CS..Hα-helixtrans-58.9-47.8173.8-178.5167.5-117.100112.2L156 N188 F189 H190 L421 M422 R423 E427 L428 G429 A432L156-E425 HydrophobicContact CD1-CB 3.45Å; L156-E425 VanDerWaalsContact CD1-CB 3.45Å; L156-E425 HydrophobicContact CD1-CG 3.48Å; L156-E425 VanDerWaalsContact CD1-CG 3.48Å; L156-E425 WeakPolarHBondContact CD1-OE1 2.92Å; L156-E425 HydrophobicContact CD2-CB 4.26Å; L156-E425 HydrophobicContact CG-CB 4.49Å; N188-E425 WeakPolarHBondContact CB-OE1 3.48Å; F189-E425 VanDerWaalsContact CB-OE1 3.3Å; F189-E425 WeakPolarHBondContact CB-OE1 3.48Å; F189-E425 PolarHBondContact N-OE1 2.66Å; H190-E425 WeakPolarHBondContact CB-OE2 3.3Å; H190-E425 IonicContact CE1-OE2 2.63Å; H190-E425 IonicContact CG-OE2 3.17Å; H190-E425 PolarHBondContact N-OE2 3.07Å; H190-E425 IonicContact ND1-OE2 2.84Å; H190-E425 PolarHBondContact ND1-OE2 3.16Å; L421-E425 WeakPolarHBondContact O-CB 3.45Å; L421-E425 PolarHBondContact O-N 3.05Å; M422-E425 PolarHBondContact O-N 2.77Å; R423-E425 VanDerWaalsContact C-N 3.3Å; R423-E425 PolarHBondContact O-N 3.18Å; E425-E427 PolarHBondContact O-N 3.01Å; E425-L428 PolarHBondContact O-N 2.91Å; E425-G429 PolarHBondContact O-N 2.9Å; E425-G429 VanDerWaalsContact O-N 3.09Å; E425-A432 HydrophobicContact CG-CB 4.15Å
426E98.8Very high98.4Very high155 Ų15555 Ų5572%0.72428%0.278SS*.Hα-helixtrans-59.7-44.2176.4-173.3-176.2113.700111.7M422 R423 L428 G429M422-E426 PolarHBondContact O-N 3.18Å; R423-E426 PolarHBondContact O-N 2.88Å; E426-L428 VanDerWaalsContact C-N 3.34Å; E426-L428 PolarHBondContact O-N 2.94Å; E426-G429 PolarHBondContact O-N 3.16Å
427E98.8Very high98.3Very high117 Ų11762 Ų6255%0.54731%0.305SS..Hα-helixtrans-64.5-36.1178.7-177.3173-16500112.7P140 Y142 R423 I424 E425 G429P140-E427 WeakPolarHBondContact CG-OE1 3.18Å; Y142-E427 WeakPolarHBondContact CE1-OE2 3.19Å; R423-E427 WeakPolarHBondContact O-CB 3.36Å; R423-E427 PolarHBondContact O-N 2.87Å; I424-E427 PolarHBondContact O-N 2.84Å; E425-E427 PolarHBondContact O-N 3.01Å; E427-G429 VanDerWaalsContact C-N 3.35Å
428L98.3Very high98.3Very high25 Ų2565 Ų6513%0.13132%0.321CS..Hα-helixtrans-72.5-27.9176.2-72.1170.1000112.6Y142 V154 I424 E425 E426 D430 K431 A432Y142-L428 HydrophobicContact CE2-CD2 3.93Å; Y142-L428 HydrophobicContact CE2-CG 4.49Å; V154-L428 HydrophobicContact CG2-CD1 3.83Å; V154-L428 HydrophobicContact CG2-CD2 3.75Å; V154-L428 HydrophobicContact CG2-CG 4.48Å; I424-L428 HydrophobicContact CG2-CD1 3.86Å; I424-L428 HydrophobicContact CG2-CG 4.35Å; I424-L428 WeakPolarHBondContact O-CB 3.21Å; I424-L428 VanDerWaalsContact O-CG 3.26Å; I424-L428 WeakPolarHBondContact O-CG 3.28Å; I424-L428 PolarHBondContact O-N 2.91Å; E425-L428 PolarHBondContact O-N 2.91Å; E426-L428 VanDerWaalsContact C-N 3.34Å; E426-L428 PolarHBondContact O-N 2.94Å; L428-D430 PolarHBondContact O-N 3.01Å; L428-K431 WeakPolarHBondContact O-CB 3.46Å; L428-K431 PolarHBondContact O-N 2.76Å; L428-A432 HydrophobicContact CB-CB 3.87Å
429G98.1Very high98.3Very high40 Ų4065.5 Ų65.541%0.41232%0.323SS..G310 helixtrans53.4-130.6-179.800000112E425 E426 E427 K431 A432E425-G429 PolarHBondContact O-N 2.9Å; E425-G429 VanDerWaalsContact O-N 3.09Å; E426-G429 PolarHBondContact O-N 3.16Å; E427-G429 VanDerWaalsContact C-N 3.35Å; G429-K431 PolarHBondContact O-N 3.12Å; G429-A432 WeakPolarHBondContact O-CB 3.5Å; G429-A432 PolarHBondContact O-N 2.81Å
430D96.6Very high98.2Very high180 Ų18065.6 Ų65.696%0.96332%0.319SS*.G310 helixtrans-61.5-12.8179.7-60.9-27000114.4L428L428-D430 PolarHBondContact O-N 3.01Å
431K95.9Very high98.2Very high172 Ų17268.6 Ų68.675%0.74833%0.333SS*.G310 helixtrans-86.8-9.4175.4-57.8178.2-176.8172.40112.7L428 G429 K433L428-K431 WeakPolarHBondContact O-CB 3.46Å; L428-K431 PolarHBondContact O-N 2.76Å; G429-K431 PolarHBondContact O-N 3.12Å; K431-K433 PolarHBondContact O-N 3.05Å
432A96.8Very high98Very high31 Ų3169.7 Ų69.726%0.25634%0.34SS..  trans-64.4118.2178.200000109.9L156 E425 L428 G429L156-A432 HydrophobicContact CD1-CB 4.03Å; E425-A432 HydrophobicContact CG-CB 4.15Å; L428-A432 HydrophobicContact CB-CB 3.87Å; G429-A432 WeakPolarHBondContact O-CB 3.5Å; G429-A432 PolarHBondContact O-N 2.81Å
433K97.8Very high97.4Very high79 Ų7974 Ų7434%0.34336%0.358SS..  trans-107.5135.2168.8-63.2-176.6-173.3178.10108.1I155 L156 K431 I444 N445I155-K433 HydrophobicContact CD1-CB 4.28Å; I155-K433 HydrophobicContact CG1-CB 4.32Å; L156-K433 WeakPolarHBondContact CB-O 3.45Å; L156-K433 PolarHBondContact N-O 2.87Å; K431-K433 PolarHBondContact O-N 3.05Å; K433-I444 PolarHBondContact NZ-O 2.93Å; K433-N445 PolarHBondContact NZ-OD1 3.47Å
434F98.6Very high96.2Very high32 Ų3269.7 Ų69.714%0.1434%0.344CS..BIsolated β-bridgetrans-106.8133.3175.2176.3-112.9000109.8L156 P157 V158 A186 F189 A192 G436L156-F434 HydrophobicContact CB-CD2 4.25Å; P157-F434 WeakPolarHBondContact O-CE2 3.42Å; V158-F434 HydrophobicContact CB-CZ 4.4Å; V158-F434 HydrophobicContact CG2-CE1 4.3Å; V158-F434 HydrophobicContact CG2-CE2 4.18Å; V158-F434 HydrophobicContact CG2-CZ 3.74Å; A186-F434 HydrophobicContact CB-CE1 3.94Å; A186-F434 HydrophobicContact CB-CZ 4.25Å; A186-F434 WeakPolarHBondContact O-CD1 3.45Å; A186-F434 VanDerWaalsContact O-CE1 3.29Å; A186-F434 WeakPolarHBondContact O-CE1 3.33Å; F189-F434 HydrophobicContact CB-CD2 4.21Å; F189-F434 HydrophobicContact CB-CE2 4.44Å; F189-F434 HydrophobicContact CD2-CE2 4.31Å; A192-F434 HydrophobicContact CB-CE2 4.09Å; A192-F434 HydrophobicContact CB-CZ 3.79Å; F434-G436 VanDerWaalsContact C-N 3.33Å; F434-G436 VanDerWaalsContact CE1-CA 3.49Å; F434-G436 PolarHBondContact O-N 3.21Å
435A98.6Very high94.1Very high6 Ų677.9 Ų77.95%0.0539%0.388CS..  trans-64.4-35.4-174.400000113.4I155 L156 V158 G402 K437 D438 P442I155-A435 HydrophobicContact CD1-CB 4.33Å; I155-A435 HydrophobicContact CG1-CB 4.19Å; L156-A435 WeakPolarHBondContact O-CB 3.37Å; L156-A435 PolarHBondContact O-N 2.62Å; V158-A435 HydrophobicContact CG2-CB 4.43Å; G402-A435 WeakPolarHBondContact O-CB 3.42Å; A435-K437 PolarHBondContact O-N 2.75Å; A435-D438 WeakPolarHBondContact O-CA 3.49Å; A435-D438 WeakPolarHBondContact O-CB 3.25Å; A435-D438 PolarHBondContact O-N 2.96Å; A435-P442 HydrophobicContact CB-CB 4.2Å; A435-P442 HydrophobicContact CB-CG 4.23Å
436G98.4Very high93.9Very high7 Ų780.8 Ų80.87%0.07240%0.403CS..G310 helixtrans49.7-127.817700000113.2V158 V184 F434 D438 F439V158-G436 VanDerWaalsContact CG2-O 3.27Å; V158-G436 WeakPolarHBondContact CG2-O 3.3Å; V184-G436 CarbonylContact O-C 3.37Å; V184-G436 VanDerWaalsContact O-C 3.26Å; V184-G436 VanDerWaalsContact O-CA 3.29Å; V184-G436 WeakPolarHBondContact O-CA 3.45Å; F434-G436 VanDerWaalsContact C-N 3.33Å; F434-G436 VanDerWaalsContact CE1-CA 3.49Å; F434-G436 PolarHBondContact O-N 3.21Å; G436-D438 PolarHBondContact O-N 3.45Å; G436-F439 WeakPolarHBondContact O-CB 3.4Å; G436-F439 PolarHBondContact O-N 2.7Å
437K97.9Very high93.7Very high168 Ų16876.8 Ų76.873%0.7339%0.386SS*.G310 helixtrans-64.6-21.2179.4-64.9-175.8178.3-177.80114V184 A435 F439V184-K437 PolarHBondContact O-N 3.44Å; A435-K437 PolarHBondContact O-N 2.75Å; K437-F439 VanDerWaalsContact C-N 3.27Å; K437-F439 PolarHBondContact O-N 3.38Å
438D98.2Very high93.4Very high65 Ų6574.6 Ų74.635%0.34838%0.377SS..G310 helixtrans-88.417179.3-66.2-41000112.2A435 G436 R440 H441 P442 K443A435-D438 WeakPolarHBondContact O-CA 3.49Å; A435-D438 WeakPolarHBondContact O-CB 3.25Å; A435-D438 PolarHBondContact O-N 2.96Å; G436-D438 PolarHBondContact O-N 3.45Å; D438-R440 PolarHBondContact O-N 3.06Å; D438-H441 CarbonylContact O-C 3.47Å; D438-H441 PolarHBondContact O-N 3.47Å; D438-P442 VanDerWaalsContact O-CA 3.32Å; D438-P442 WeakPolarHBondContact O-CA 3.35Å; D438-K443 VanDerWaalsContact CG-NZ 3.29Å; D438-K443 IonicContact OD1-NZ 3.37Å; D438-K443 PolarHBondContact OD1-NZ 3.38Å; D438-K443 VanDerWaalsContact OD1-NZ 3.07Å; D438-K443 WeakPolarHBondContact OD2-CE 3.28Å; D438-K443 IonicContact OD2-NZ 2.84Å; D438-K443 PolarHBondContact OD2-NZ 3.19Å
439F98.6Very high93.1Very high10 Ų1077.5 Ų77.54%0.04439%0.391CS..THydrogen-bonded Turntrans-52.6-29.1-175.378.5-81.2000115.6V158 L182 V184 I252 Q403 G436 K437V158-F439 HydrophobicContact CB-CB 4.07Å; V158-F439 HydrophobicContact CG2-CB 3.7Å; L182-F439 HydrophobicContact CD2-CE2 4.39Å; V184-F439 HydrophobicContact CG1-CD1 3.87Å; V184-F439 HydrophobicContact CG1-CE1 4.21Å; I252-F439 HydrophobicContact CD1-CE1 3.73Å; I252-F439 HydrophobicContact CD1-CZ 3.89Å; Q403-F439 HydrophobicContact CB-CB 4.43Å; Q403-F439 HydrophobicContact CB-CD2 4.04Å; Q403-F439 VanDerWaalsContact CD-CD2 3.49Å; Q403-F439 HydrophobicContact CG-CD2 4.23Å; Q403-F439 PolarHBondContact NE2-O 3.2Å; G436-F439 WeakPolarHBondContact O-CB 3.4Å; G436-F439 PolarHBondContact O-N 2.7Å; K437-F439 VanDerWaalsContact C-N 3.27Å; K437-F439 PolarHBondContact O-N 3.38Å
440R98.4Very high92.8Very high59 Ų5979.9 Ų79.922%0.22339%0.39CS..THydrogen-bonded Turntrans-70-40.6176.3-63.2174.666.2176.91.9111.9D323 I324 Q325 N349 G377 D438D323-R440 PolarHBondContact O-NH1 2.87Å; I324-R440 PolarHBondContact O-NH2 3.44Å; Q325-R440 HydrophobicContact CB-CG 4.48Å; N349-R440 PolarHBondContact ND2-NH2 3.35Å; G377-R440 WeakPolarHBondContact CA-O 3.07Å; D438-R440 PolarHBondContact O-N 3.06Å
441H97.1Very high92.5Very high100 Ų10073.2 Ų73.246%0.46335%0.352SS..SBendtrans-142.477.8-176.1-58.3-57.9000109.8G375 D438 K443G375-H441 PolarHBondContact O-CE1 3.26Å; D438-H441 CarbonylContact O-C 3.47Å; D438-H441 PolarHBondContact O-N 3.47Å; H441-K443 PolarHBondContact O-N 3.29Å
442P94.8Very high92.3Very high23 Ų2366.1 Ų66.115%0.14932%0.323CS..  trans-64.1136.3-171.5-20.632.9000111.4I155 G402 A435 D438 I444I155-P442 HydrophobicContact CD1-CB 3.5Å; I155-P442 VanDerWaalsContact CD1-CB 3.5Å; I155-P442 HydrophobicContact CG1-CB 4.22Å; I155-P442 HydrophobicContact CG2-CB 4.11Å; G402-P442 VanDerWaalsContact CA-CG 3.46Å; A435-P442 HydrophobicContact CB-CB 4.2Å; A435-P442 HydrophobicContact CB-CG 4.23Å; D438-P442 VanDerWaalsContact O-CA 3.32Å; D438-P442 WeakPolarHBondContact O-CA 3.35Å; P442-I444 PolarHBondContact O-N 3.29Å
443K86.2Confident91.9Very high131 Ų13168.8 Ų68.857%0.5733%0.329SS*.  trans-80.192.5176-65.9176.7-169.8126.90109.4D438 H441 N445D438-K443 VanDerWaalsContact CG-NZ 3.29Å; D438-K443 IonicContact OD1-NZ 3.37Å; D438-K443 PolarHBondContact OD1-NZ 3.38Å; D438-K443 VanDerWaalsContact OD1-NZ 3.07Å; D438-K443 WeakPolarHBondContact OD2-CE 3.28Å; D438-K443 IonicContact OD2-NZ 2.84Å; D438-K443 PolarHBondContact OD2-NZ 3.19Å; H441-K443 PolarHBondContact O-N 3.29Å; K443-N445 PolarHBondContact O-N 2.64Å
444I74.4Confident91.4Very high41 Ų4168 Ų6821%0.2133%0.327CS..  trans-72.5-23.6-177.7-61.6162.8000110.4D153 I155 C400 K433 P442D153-I444 HydrophobicContact CB-CG2 3.75Å; I155-I444 HydrophobicContact CG2-CG1 4.39Å; C400-I444 HydrophobicContact CB-CD1 3.36Å; C400-I444 HydrophobicContact CB-CG1 4.06Å; K433-I444 PolarHBondContact NZ-O 2.93Å; P442-I444 PolarHBondContact O-N 3.29Å
445N56.1Low90.8Very high174 Ų17471.3 Ų71.393%0.9334%0.344SS*.  trans-146.80167.6-77.5-46000113.4D153 K433 K443D153-N445 PolarHBondContact OD2-ND2 2.94Å; D153-N445 PolarHBondContact OD2-OD1 3.03Å; K433-N445 PolarHBondContact NZ-OD1 3.47Å; K443-N445 PolarHBondContact O-N 2.64Å

Retrieved 445 of 445 residues in 463.4 ms (Link to these results)