A0A087YE66_POEFO Loading...

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AlphaFold DB , UniProt , Accession A0A087YE66, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 624 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.1	Very low	31.3	Very low	225 Å²	225	164.3 Å²	164.3	100%	1.108	83%	0.825	S	S	*	*				0	76.4	0	-150.7	164.3	167.8	0	0	105.4
2	N	32.5	Very low	31.1	Very low	155 Å²	155	159.9 Å²	159.9	83%	0.829	82%	0.821	S	S	*	*				49.9	118.4	68.8	-89.5	-2	0	0	0	111.5
3	I	32.9	Very low	31.1	Very low	148 Å²	148	156.4 Å²	156.4	76%	0.759	82%	0.819	S	S	*	*			trans	154.9	133.5	146.8	-81.2	154.6	0	0	0	104.3
4	Q	32.7	Very low	30.9	Very low	164 Å²	164	155.9 Å²	155.9	77%	0.766	83%	0.825	S	S	*	*			cis	178	167.3	-7.3	-167.8	172.3	22.9	0	0	102.6
5	I	30.2	Very low	30.9	Very low	168 Å²	168	151.2 Å²	151.2	86%	0.862	82%	0.818	S	S	*	*			trans	140.1	135.1	152	-68	153.9	0	0	0	110.8
6	L	27	Very low	31	Very low	153 Å²	153	149.6 Å²	149.6	80%	0.801	82%	0.817	S	S	*	*			trans	-125.6	176	-178.4	-157.3	99.1	0	0	0	106.8
7	P	43.8	Very low	30.9	Very low	108 Å²	108	151.4 Å²	151.4	70%	0.701	83%	0.825	S	S	*	*				-120.4	168	-63.3	31.8	-17	0	0	0	113.3
8	E	26.2	Very low	30.7	Very low	176 Å²	176	153.9 Å²	153.9	82%	0.822	83%	0.826	S	S	*	*			trans	-156.6	149.1	147.3	-122.3	-179.3	-163.5	0	0	113
9	H	30.5	Very low	30.5	Very low	145 Å²	145	155.3 Å²	155.3	67%	0.671	83%	0.827	S	S	*	*			trans	84.6	102.5	159.8	-87.7	-77.8	0	0	0	123.8
10	K	27.1	Very low	30.3	Very low	182 Å²	182	153.4 Å²	153.4	79%	0.791	83%	0.826	S	S	*	*			trans	43.8	116.8	133.8	-71.7	-176.5	178.8	177.5	0	121
11	L	27.1	Very low	30.3	Very low	183 Å²	183	153.4 Å²	153.4	96%	0.958	83%	0.825	S	S	*	*				-160	119.1	123.4	-132.1	92.7	0	0	0	109.6
12	S	29.8	Very low	30.1	Very low	112 Å²	112	148.5 Å²	148.5	78%	0.783	81%	0.808	S	S	*	*			trans	-127.2	108.1	171.3	60	0	0	0	0	110.9
13	S	30	Very low	30.1	Very low	114 Å²	114	149.4 Å²	149.4	80%	0.797	81%	0.807	S	S	*	*			trans	38	120.5	143.4	60.2	0	0	0	0	120.7
14	V	29.2	Very low	29.9	Very low	149 Å²	149	151.8 Å²	151.8	90%	0.903	81%	0.812	S	S	*	*			trans	-74.2	136.8	163.2	176	0	0	0	0	110.6
15	A	30.6	Very low	30	Very low	86 Å²	86	152.1 Å²	152.1	71%	0.711	81%	0.811	S	S	*	*			trans	-131.9	156.5	165.2	0	0	0	0	0	108.9
16	P	32.2	Very low	30	Very low	125 Å²	125	153.5 Å²	153.5	81%	0.812	81%	0.814	S	S	*	*	P	Polyproline II helix	trans	-80.2	155.5	-141.3	30.3	-34.7	0	0	0	116	K18	P16-K18 PolarHBondContact O-N 3.37Å
17	L	28.9	Very low	30.3	Very low	181 Å²	181	151.6 Å²	151.6	95%	0.948	81%	0.808	S	S	*	*	P	Polyproline II helix	trans	-51.2	118.6	174.6	-95.5	123.4	0	0	0	112.1
18	K	27.9	Very low	29.6	Very low	196 Å²	196	155.2 Å²	155.2	85%	0.852	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-84.4	126.9	162.2	-127.2	177.1	-177.7	-179.1	0	108.1	P16 C20	P16-K18 PolarHBondContact O-N 3.37Å; K18-C20 PolarHBondContact O-N 3.4Å
19	Q	27	Very low	29.7	Very low	181 Å²	181	153.7 Å²	153.7	85%	0.846	81%	0.812	S	S	*	*	P	Polyproline II helix	trans	-52.4	116.1	176.9	-139.4	159.6	-12.3	0	0	109.9	D21	Q19-D21 PolarHBondContact O-N 3.4Å
20	C	26.9	Very low	29.8	Very low	117 Å²	117	153.7 Å²	153.7	79%	0.791	82%	0.816	S	S	*	*			trans	-80.9	104.9	167.3	-89.7	0	0	0	0	108.1	K18 V22	K18-C20 PolarHBondContact O-N 3.4Å; C20-V22 VanDerWaalsContact C-N 3.34Å; C20-V22 PolarHBondContact O-N 3.5Å
21	D	28.9	Very low	30	Very low	154 Å²	154	152.7 Å²	152.7	82%	0.824	82%	0.818	S	S	*	*			trans	-67.6	96.3	160.9	-78.9	-36.7	0	0	0	108.1	Q19 E23	Q19-D21 PolarHBondContact O-N 3.4Å; D21-E23 PolarHBondContact O-N 3.09Å
22	V	30.9	Very low	30.3	Very low	122 Å²	122	150 Å²	150	74%	0.739	81%	0.809	S	S	*	*			trans	-74.8	108.6	168.5	179.7	0	0	0	0	107.2	C20 K24	C20-V22 VanDerWaalsContact C-N 3.34Å; C20-V22 PolarHBondContact O-N 3.5Å; V22-K24 PolarHBondContact O-N 3.06Å
23	E	32.8	Very low	30.4	Very low	174 Å²	174	153.7 Å²	153.7	81%	0.813	81%	0.811	S	S	*	*			trans	-62.5	107.2	171.8	-150.1	-179.5	-155	0	0	108.6	D21 K25	D21-E23 PolarHBondContact O-N 3.09Å; E23-K25 PolarHBondContact O-N 3.29Å; E23-K25 VanDerWaalsContact O-N 3.09Å
24	K	28.7	Very low	30.7	Very low	198 Å²	198	155.2 Å²	155.2	86%	0.861	81%	0.81	S	S	*	*			trans	-68.6	105.3	173.7	-77.7	-178.3	178.1	178.3	0	108.4	V22 E26	V22-K24 PolarHBondContact O-N 3.06Å; K24-E26 PolarHBondContact O-N 3.39Å
25	K	33.9	Very low	31.2	Very low	171 Å²	171	155.6 Å²	155.6	74%	0.743	80%	0.802	S	S	*	*			trans	-79.4	113.8	161.4	-85.2	-179.8	175.6	174.8	0	108.7	E23 V27	E23-K25 PolarHBondContact O-N 3.29Å; E23-K25 VanDerWaalsContact O-N 3.09Å; K25-V27 PolarHBondContact O-N 3.03Å
26	E	30.1	Very low	31.5	Very low	196 Å²	196	159.2 Å²	159.2	92%	0.916	81%	0.81	S	S	*	*			trans	-66.5	123.7	162	-74.3	-175.8	161.5	0	0	108.3	K24	K24-E26 PolarHBondContact O-N 3.39Å
27	V	33	Very low	31.7	Very low	113 Å²	113	156.7 Å²	156.7	69%	0.685	81%	0.806	S	S	*	*			trans	-113.8	109.8	174.6	-179.1	0	0	0	0	106	K25 L29	K25-V27 PolarHBondContact O-N 3.03Å; V27-L29 PolarHBondContact O-N 3.21Å
28	E	28.9	Very low	32.1	Very low	185 Å²	185	154.6 Å²	154.6	86%	0.864	80%	0.801	S	S	*	*			trans	-81.4	111.9	172.8	-151.6	176.2	-164.3	0	0	108.7
29	L	29.1	Very low	32.4	Very low	143 Å²	143	154.4 Å²	154.4	75%	0.749	80%	0.803	S	S	*	*			trans	-93.4	106.7	179.2	-95.9	145.8	0	0	0	109.3	V27 L31	V27-L29 PolarHBondContact O-N 3.21Å; L29-L31 PolarHBondContact O-N 3.47Å
30	I	33	Very low	32.6	Very low	145 Å²	145	156.1 Å²	156.1	74%	0.744	80%	0.803	S	S	*	*			trans	-83.5	105.8	169.7	-58.9	175.8	0	0	0	108.1	V32	I30-V32 HydrophobicContact CG2-CG2 4.2Å
31	L	30.4	Very low	32.9	Very low	162 Å²	162	157.3 Å²	157.3	85%	0.848	81%	0.807	S	S	*	*			trans	-86.3	103.8	172.1	-86.1	160.3	0	0	0	109.8	L29	L29-L31 PolarHBondContact O-N 3.47Å
32	V	34.2	Very low	32.8	Very low	125 Å²	125	155.7 Å²	155.7	76%	0.758	81%	0.808	S	S	*	*			trans	-89.8	113.7	164.5	-178.2	0	0	0	0	107.8	I30	I30-V32 HydrophobicContact CG2-CG2 4.2Å
33	K	30.7	Very low	32.8	Very low	191 Å²	191	155.5 Å²	155.5	83%	0.83	81%	0.812	S	S	*	*			trans	-95	114	172.7	-176.7	179.2	-177.8	178.5	0	108.3
34	D	38.1	Very low	32.7	Very low	146 Å²	146	152.4 Å²	152.4	78%	0.781	81%	0.809	S	S	*	*			trans	-127.6	142.4	162.5	-144.4	-8.7	0	0	0	110.2
35	Q	39.7	Very low	32.7	Very low	156 Å²	156	150.5 Å²	150.5	73%	0.729	81%	0.807	S	S	*	*	S	Bend	trans	-76.9	127.2	-170.8	-72	-179.3	-19.7	0	0	110.3
36	N	36.3	Very low	32.5	Very low	163 Å²	163	149.7 Å²	149.7	87%	0.872	81%	0.809	S	S	*	*	S	Bend	trans	97.1	72.2	171.1	-50	-22.4	0	0	0	117
37	G	35.3	Very low	32.4	Very low	71 Å²	71	145.5 Å²	145.5	73%	0.732	80%	0.801	S	S	*	*				79.7	102.5	126	0	0	0	0	0	119.5
38	V	37.2	Very low	32	Very low	138 Å²	138	146.4 Å²	146.4	84%	0.836	81%	0.807	S	S	*	*			trans	93.6	110.8	154.8	-161.7	0	0	0	0	117
39	Q	35.8	Very low	32.2	Very low	191 Å²	191	143.8 Å²	143.8	89%	0.893	81%	0.806	S	S	*	*			trans	-143.8	139.5	162.3	-119.6	-175.2	6	0	0	112.8
40	Y	30.3	Very low	32.2	Very low	218 Å²	218	140.3 Å²	140.3	86%	0.855	81%	0.805	S	S	*	*			trans	-80.2	133.6	173	-69.4	-96.1	0	0	0	110.2
41	T	32.6	Very low	31.9	Very low	142 Å²	142	141.4 Å²	141.4	87%	0.871	81%	0.812	S	S	*	*			trans	-88.7	113.4	177	50.7	0	0	0	0	111.3
42	S	28.4	Very low	31.8	Very low	120 Å²	120	144.9 Å²	144.9	84%	0.839	81%	0.814	S	S	*	*			trans	-100.2	119.1	158.7	-74.8	0	0	0	0	109.3
43	S	30.3	Very low	31.6	Very low	118 Å²	118	145.8 Å²	145.8	83%	0.825	82%	0.819	S	S	*	*			trans	-86.6	107.5	174.5	35.8	0	0	0	0	110.2
44	S	29.9	Very low	31.5	Very low	108 Å²	108	139.9 Å²	139.9	76%	0.755	81%	0.813	S	S	*	*			trans	-93.5	118.8	165.9	50	0	0	0	0	109.7
45	I	29.9	Very low	31	Very low	159 Å²	159	140.8 Å²	140.8	82%	0.815	82%	0.817	S	S	*	*			trans	-83.5	113.4	174.6	-60.9	172.3	0	0	0	107.5
46	I	29.1	Very low	30.5	Very low	154 Å²	154	139.7 Å²	139.7	79%	0.79	82%	0.823	S	S	*	*	P	Polyproline II helix	trans	-87.3	122.3	166.9	-61	174.5	0	0	0	107.4
47	S	28.5	Very low	30.3	Very low	107 Å²	107	135.9 Å²	135.9	75%	0.748	82%	0.823	S	S	*	*	P	Polyproline II helix	trans	-92.7	123.7	178.1	46.1	0	0	0	0	111.7
48	T	25.3	Very low	29.9	Very low	132 Å²	132	136.9 Å²	136.9	81%	0.81	82%	0.824	S	S	*	*	P	Polyproline II helix	trans	-76.8	145.3	172.9	-32.1	0	0	0	0	110.5	G50	T48-G50 PolarHBondContact O-N 3.29Å
49	P	32.6	Very low	29.4	Very low	130 Å²	130	135.2 Å²	135.2	84%	0.844	82%	0.818	S	S	*	*			trans	-87.5	113.9	-173.5	31.8	-29.4	0	0	0	111.9
50	G	27.8	Very low	29.4	Very low	70 Å²	70	131.2 Å²	131.2	72%	0.722	81%	0.809	S	S	*	*			trans	-177.5	117	169.8	0	0	0	0	0	114.2	T48	T48-G50 PolarHBondContact O-N 3.29Å
51	N	26.9	Very low	30	Very low	169 Å²	169	129.4 Å²	129.4	90%	0.904	81%	0.808	S	S	*	*			trans	52.5	97.3	163	-72.9	-10.4	0	0	0	119.8
52	R	29.9	Very low	30.8	Very low	235 Å²	235	125.9 Å²	125.9	89%	0.887	80%	0.8	S	S	*	*	P	Polyproline II helix	trans	-79.5	116.1	163.3	-69.5	-178.8	177.9	-179.7	0.2	110.7
53	V	29.5	Very low	32.6	Very low	143 Å²	143	127.7 Å²	127.7	87%	0.867	80%	0.8	S	S	*	*	P	Polyproline II helix	trans	-99.1	117.6	147.3	178.3	0	0	0	0	106.2
54	G	28.6	Very low	35.1	Very low	68 Å²	68	124 Å²	124	70%	0.701	77%	0.768	S	S	*	*	P	Polyproline II helix	trans	-78.8	135.9	-168.9	0	0	0	0	0	113.8
55	L	27	Very low	37.9	Very low	165 Å²	165	122.7 Å²	122.7	86%	0.864	75%	0.75	S	S	*	*	P	Polyproline II helix	trans	-79.9	136.4	154.4	-86	114.9	0	0	0	109.7	G57	L55-G57 PolarHBondContact O-N 3.41Å
56	P	30.2	Very low	40.9	Very low	133 Å²	133	117.6 Å²	117.6	86%	0.864	73%	0.726	S	S	*	*	T	Hydrogen-bonded Turn	trans	-81.4	110.9	175.5	30.7	-28.3	0	0	0	109.6
57	G	31.4	Very low	43.9	Very low	83 Å²	83	110.9 Å²	110.9	86%	0.856	69%	0.691	S	S	*	*	T	Hydrogen-bonded Turn	trans	151.9	-13.6	167.9	0	0	0	0	0	117.8	L55	L55-G57 PolarHBondContact O-N 3.41Å
58	A	26.6	Very low	46.8	Very low	92 Å²	92	109 Å²	109	76%	0.76	69%	0.688	S	S	*	*			trans	-105.2	105	176.2	0	0	0	0	0	110.6
59	S	27.6	Very low	50	Low	102 Å²	102	109.2 Å²	109.2	71%	0.713	68%	0.678	S	S	*	*			trans	-63.8	124.8	162.3	49.1	0	0	0	0	108.5	E61	S59-E61 PolarHBondContact O-N 2.77Å
60	P	35.2	Very low	52.8	Low	108 Å²	108	107.6 Å²	107.6	70%	0.701	66%	0.658	S	S	*	*			trans	-67	103.5	173.4	26	-30	0	0	0	108.7	G62	P60-G62 PolarHBondContact O-N 3.33Å; P60-G62 VanDerWaalsContact O-N 3.15Å
61	E	42.3	Very low	56	Low	180 Å²	180	107.7 Å²	107.7	84%	0.841	64%	0.641	S	S	*	*	S	Bend	trans	-65.3	103.3	155.3	-73.7	-169.9	150.5	0	0	106.4	S59	S59-E61 PolarHBondContact O-N 2.77Å
62	G	50.4	Low	59.2	Low	67 Å²	67	100.4 Å²	100.4	69%	0.691	60%	0.602	S	S	*	*			trans	-178.8	-50.4	177.7	0	0	0	0	0	117.2	P60	P60-G62 PolarHBondContact O-N 3.33Å; P60-G62 VanDerWaalsContact O-N 3.15Å
63	D	65.3	Low	62.3	Low	158 Å²	158	89.3 Å²	89.3	85%	0.845	56%	0.56	S	S	*	*			trans	-111.7	106.9	-169.7	-81.5	-31.3	0	0	0	112.8
64	R	83.2	Confident	65.5	Low	42 Å²	42	83.5 Å²	83.5	16%	0.158	52%	0.524	C	S	.	.			trans	-57.3	136.5	162.1	-174.5	179.6	-170.2	97.5	5.6	108.1	R129 S338 Y339 D440	R64-R129 VanDerWaalsContact CD-O 3.25Å; R64-R129 WeakPolarHBondContact CD-O 2.75Å; R64-R129 VanDerWaalsContact CZ-O 3.27Å; R64-R129 PolarHBondContact NE-O 3.46Å; R64-R129 PolarHBondContact NH1-O 2.69Å; R64-S338 VanDerWaalsContact CD-O 3.26Å; R64-S338 WeakPolarHBondContact CD-O 3.43Å; R64-S338 PolarHBondContact NE-O 2.95Å; R64-S338 PolarHBondContact NE-OG 3.31Å; R64-S338 VanDerWaalsContact NE-OG 3.13Å; R64-S338 PolarHBondContact NH2-OG 3.32Å; R64-Y339 HydrophobicContact CG-CD1 3.98Å; R64-Y339 HydrophobicContact CG-CE1 4.06Å; R64-D440 IonicContact CZ-OD2 3.45Å; R64-D440 VanDerWaalsContact CZ-OD2 3.28Å; R64-D440 VanDerWaalsContact NH1-CG 3.35Å; R64-D440 IonicContact NH1-OD1 3.16Å; R64-D440 PolarHBondContact NH1-OD1 3.15Å; R64-D440 IonicContact NH1-OD2 2.76Å; R64-D440 PolarHBondContact NH1-OD2 3.14Å; R64-D440 IonicContact NH2-OD1 3.11Å; R64-D440 IonicContact NH2-OD2 3.71Å; R64-D440 PolarHBondContact NH2-OD2 2.6Å
65	E	89.1	Confident	68.7	Low	79 Å²	79	81.4 Å²	81.4	37%	0.369	50%	0.497	S	S	.	.			trans	-55.2	153	176.4	-59.8	-161.7	122.3	0	0	111.1	K264 Y339	E65-K264 IonicContact OE1-NZ 2.89Å; E65-K264 PolarHBondContact OE1-NZ 3.37Å; E65-Y339 VanDerWaalsContact O-CD1 3.32Å; E65-Y339 WeakPolarHBondContact O-CD1 3.45Å
66	T	92.3	Very high	72	Confident	52 Å²	52	73.7 Å²	73.7	32%	0.319	46%	0.457	S	S	.	.			trans	-128.6	158.3	178.2	53.4	0	0	0	0	110.6	Y339	T66-Y339 VanDerWaalsContact CA-O 3.27Å; T66-Y339 WeakPolarHBondContact CA-O 3.46Å; T66-Y339 WeakPolarHBondContact CB-O 3.14Å
67	W	93.1	Very high	75.1	Confident	14 Å²	14	67.4 Å²	67.4	5%	0.053	42%	0.416	C	S	.	.			trans	-56.8	141.2	171.7	-63.9	102.1	0	0	0	111.2	D72 F73 S76 V263 F336 Y339 N340	W67-D72 HydrophobicContact CE3-CB 3.95Å; W67-F73 HydrophobicContact CB-CB 4.42Å; W67-F73 HydrophobicContact CD2-CB 3.92Å; W67-F73 AromaticContact CE2-CD2 3.96Å; W67-F73 HydrophobicContact CG-CB 3.79Å; W67-F73 HydrophobicContact CZ2-CD2 4.29Å; W67-F73 AromaticContact NE1-CD2 3.54Å; W67-S76 WeakPolarHBondContact CH2-OG 3.41Å; W67-S76 WeakPolarHBondContact CZ3-OG 3.48Å; W67-V263 HydrophobicContact CD2-CB 4.12Å; W67-V263 HydrophobicContact CD2-CG1 4.47Å; W67-V263 HydrophobicContact CE3-CB 3.86Å; W67-V263 HydrophobicContact CE3-CG1 4.45Å; W67-V263 HydrophobicContact CH2-CB 3.86Å; W67-V263 HydrophobicContact CH2-CG1 3.64Å; W67-V263 HydrophobicContact CZ2-CB 4.11Å; W67-V263 HydrophobicContact CZ2-CG1 3.64Å; W67-V263 HydrophobicContact CZ3-CB 3.72Å; W67-V263 HydrophobicContact CZ3-CG1 4.06Å; W67-F336 HydrophobicContact CH2-CD1 4.21Å; W67-F336 HydrophobicContact CH2-CE1 4.4Å; W67-F336 HydrophobicContact CZ2-CB 4.08Å; W67-F336 AromaticContact CZ2-CD1 3.93Å; W67-F336 HydrophobicContact CZ2-CD1 3.93Å; W67-F336 HydrophobicContact CZ2-CG 4.08Å; W67-F336 PolarHBondContact NE1-O 3.32Å; W67-Y339 PolarHBondContact N-O 3.02Å; W67-N340 PolarHBondContact NE1-OD1 3.42Å
68	G	88.6	Confident	78.2	Confident	66 Å²	66	64.1 Å²	64.1	68%	0.68	38%	0.378	S	S	*	.	S	Bend	trans	-62.9	-47.5	179.5	0	0	0	0	0	111.5	D72	G68-D72 PolarHBondContact N-OD2 3.36Å
69	K	92	Very high	81.4	Confident	138 Å²	138	59.9 Å²	59.9	60%	0.6	34%	0.343	S	S	*	.	S	Bend	trans	-132.1	157.8	173.4	-58.2	176.5	-177.7	175.1	0	110.5	I71 D72	K69-I71 HydrophobicContact CB-CG2 3.88Å; K69-I71 HydrophobicContact CD-CG2 4.36Å; K69-I71 PolarHBondContact O-N 3.21Å; K69-D72 PolarHBondContact N-OD2 3.48Å; K69-D72 VanDerWaalsContact O-CB 3.32Å; K69-D72 WeakPolarHBondContact O-CB 3.47Å; K69-D72 PolarHBondContact O-N 2.99Å; K69-D72 VanDerWaalsContact O-N 3.1Å
70	K	92	Very high	84.7	Confident	95 Å²	95	55.9 Å²	55.9	41%	0.413	31%	0.313	S	S	.	.	H	α-helix	trans	-59.8	-35.8	175.3	177	168.8	175.1	144.5	0	112.6	D72 F73 L74 N344 D349	K70-D72 VanDerWaalsContact C-N 3.26Å; K70-D72 PolarHBondContact O-N 2.67Å; K70-F73 WeakPolarHBondContact O-CB 3.14Å; K70-F73 PolarHBondContact O-N 2.64Å; K70-L74 PolarHBondContact O-N 3.46Å; K70-L74 VanDerWaalsContact O-N 3.08Å; K70-N344 WeakPolarHBondContact CD-OD1 3.37Å; K70-N344 WeakPolarHBondContact CE-OD1 3.01Å; K70-N344 PolarHBondContact NZ-OD1 3.05Å; K70-D349 WeakPolarHBondContact CE-OD1 3.22Å; K70-D349 WeakPolarHBondContact CE-OD2 3.44Å; K70-D349 VanDerWaalsContact NZ-CG 3.35Å; K70-D349 IonicContact NZ-OD1 3.48Å; K70-D349 PolarHBondContact NZ-OD1 3.37Å; K70-D349 IonicContact NZ-OD2 3.29Å; K70-D349 PolarHBondContact NZ-OD2 3.47Å; K70-D349 VanDerWaalsContact NZ-OD2 3.11Å
71	I	93.9	Very high	87.5	Confident	72 Å²	72	50.8 Å²	50.8	37%	0.369	28%	0.28	S	S	.	.	H	α-helix	trans	-66.7	-28.8	178.1	-172.7	62.9	0	0	0	112	K69 F73 L74 L75 Y271	K69-I71 HydrophobicContact CB-CG2 3.88Å; K69-I71 HydrophobicContact CD-CG2 4.36Å; K69-I71 PolarHBondContact O-N 3.21Å; I71-F73 VanDerWaalsContact C-N 3.34Å; I71-L74 HydrophobicContact CD1-CB 4.44Å; I71-L74 HydrophobicContact CD1-CD2 4.11Å; I71-L74 PolarHBondContact O-N 2.83Å; I71-L75 HydrophobicContact CD1-CD1 4.36Å; I71-L75 HydrophobicContact CD1-CD2 4.47Å; I71-L75 HydrophobicContact CD1-CG 3.99Å; I71-L75 HydrophobicContact CG1-CD1 3.92Å; I71-L75 HydrophobicContact CG1-CG 4.03Å; I71-L75 WeakPolarHBondContact O-CB 3.42Å; I71-L75 WeakPolarHBondContact O-CG 3.37Å; I71-L75 PolarHBondContact O-N 2.93Å; I71-Y271 WeakPolarHBondContact CG2-OH 3.5Å
72	D	94.9	Very high	90	Very high	17 Å²	17	42.5 Å²	42.5	9%	0.091	24%	0.242	C	C	.	.	H	α-helix	trans	-62	-46.7	176.2	-52	-10.3	0	0	0	109.4	W67 G68 K69 K70 S76 Y271	W67-D72 HydrophobicContact CE3-CB 3.95Å; G68-D72 PolarHBondContact N-OD2 3.36Å; K69-D72 PolarHBondContact N-OD2 3.48Å; K69-D72 VanDerWaalsContact O-CB 3.32Å; K69-D72 WeakPolarHBondContact O-CB 3.47Å; K69-D72 PolarHBondContact O-N 2.99Å; K69-D72 VanDerWaalsContact O-N 3.1Å; K70-D72 VanDerWaalsContact C-N 3.26Å; K70-D72 PolarHBondContact O-N 2.67Å; D72-S76 WeakPolarHBondContact O-CB 3.05Å; D72-S76 PolarHBondContact O-N 2.95Å; D72-S76 PolarHBondContact O-OG 2.68Å; D72-Y271 WeakPolarHBondContact OD1-CE2 3.43Å; D72-Y271 VanDerWaalsContact OD1-CZ 3.31Å; D72-Y271 PolarHBondContact OD1-OH 3.46Å
73	F	95.7	Very high	92	Very high	1 Å²	1	40.5 Å²	40.5	0%	0.004	22%	0.215	C	C	.	.	H	α-helix	trans	-59.6	-51.3	173.1	166	-109.1	0	0	0	111.8	W67 K70 I71 L75 S76 V77 L122 F336 N340 D349	W67-F73 HydrophobicContact CB-CB 4.42Å; W67-F73 HydrophobicContact CD2-CB 3.92Å; W67-F73 AromaticContact CE2-CD2 3.96Å; W67-F73 HydrophobicContact CG-CB 3.79Å; W67-F73 HydrophobicContact CZ2-CD2 4.29Å; W67-F73 AromaticContact NE1-CD2 3.54Å; K70-F73 WeakPolarHBondContact O-CB 3.14Å; K70-F73 PolarHBondContact O-N 2.64Å; I71-F73 VanDerWaalsContact C-N 3.34Å; F73-L75 PolarHBondContact O-N 3.19Å; F73-S76 PolarHBondContact O-N 2.73Å; F73-S76 VanDerWaalsContact O-N 3.16Å; F73-V77 HydrophobicContact CD2-CG2 3.8Å; F73-V77 HydrophobicContact CE1-CG2 4.34Å; F73-V77 HydrophobicContact CE2-CG2 3.34Å; F73-V77 HydrophobicContact CG-CG2 4.47Å; F73-V77 HydrophobicContact CZ-CG2 3.65Å; F73-V77 WeakPolarHBondContact O-CG2 3.27Å; F73-V77 PolarHBondContact O-N 3.2Å; F73-L122 HydrophobicContact CE2-CD2 4.38Å; F73-L122 HydrophobicContact CZ-CD2 3.97Å; F73-F336 HydrophobicContact CD2-CB 4.36Å; F73-F336 HydrophobicContact CE2-CB 4.11Å; F73-N340 WeakPolarHBondContact CD2-OD1 3.48Å; F73-N340 VanDerWaalsContact CE1-ND2 3.31Å; F73-N340 WeakPolarHBondContact CE1-ND2 3.18Å; F73-N340 WeakPolarHBondContact CE2-ND2 3.48Å; F73-N340 WeakPolarHBondContact CG-OD1 3.22Å; F73-N340 WeakPolarHBondContact CZ-ND2 3.26Å; F73-D349 HydrophobicContact CE1-CB 3.95Å
74	L	95.7	Very high	93.1	Very high	22 Å²	22	33 Å²	33	12%	0.115	18%	0.175	C	C	.	.	H	α-helix	trans	-60.9	-44.1	-176.5	-176.9	67	0	0	0	111.7	K70 I71 V77 I78 L352 T353	K70-L74 PolarHBondContact O-N 3.46Å; K70-L74 VanDerWaalsContact O-N 3.08Å; I71-L74 HydrophobicContact CD1-CB 4.44Å; I71-L74 HydrophobicContact CD1-CD2 4.11Å; I71-L74 PolarHBondContact O-N 2.83Å; L74-V77 PolarHBondContact O-N 3.31Å; L74-I78 HydrophobicContact CD1-CD1 4.11Å; L74-I78 HydrophobicContact CD1-CG1 4.5Å; L74-I78 HydrophobicContact CD2-CD1 4.47Å; L74-I78 HydrophobicContact CG-CD1 3.84Å; L74-I78 WeakPolarHBondContact O-CB 3.43Å; L74-I78 VanDerWaalsContact O-CG1 3.25Å; L74-I78 WeakPolarHBondContact O-CG1 3.42Å; L74-I78 PolarHBondContact O-N 2.92Å; L74-L352 HydrophobicContact CD1-CD2 4Å; L74-L352 HydrophobicContact CD1-CG 4.46Å; L74-L352 HydrophobicContact CD2-CD2 3.63Å; L74-L352 HydrophobicContact CG-CD2 4.44Å; L74-T353 WeakPolarHBondContact CD1-OG1 3.48Å
75	L	95.9	Very high	93.5	Very high	24 Å²	24	31.4 Å²	31.4	13%	0.126	17%	0.171	C	C	.	.	H	α-helix	trans	-66.8	-37	176	-70.5	176.7	0	0	0	111.9	I71 F73 I78 G79 V270 Y271 A274 T275	I71-L75 HydrophobicContact CD1-CD1 4.36Å; I71-L75 HydrophobicContact CD1-CD2 4.47Å; I71-L75 HydrophobicContact CD1-CG 3.99Å; I71-L75 HydrophobicContact CG1-CD1 3.92Å; I71-L75 HydrophobicContact CG1-CG 4.03Å; I71-L75 WeakPolarHBondContact O-CB 3.42Å; I71-L75 WeakPolarHBondContact O-CG 3.37Å; I71-L75 PolarHBondContact O-N 2.93Å; F73-L75 PolarHBondContact O-N 3.19Å; L75-I78 PolarHBondContact O-N 3.14Å; L75-G79 PolarHBondContact O-N 3.01Å; L75-V270 HydrophobicContact CB-CB 4.44Å; L75-V270 HydrophobicContact CB-CG2 4.08Å; L75-Y271 HydrophobicContact CD1-CD1 3.95Å; L75-Y271 HydrophobicContact CD1-CD2 4.45Å; L75-Y271 HydrophobicContact CD1-CE1 4.08Å; L75-Y271 HydrophobicContact CD1-CG 4.17Å; L75-A274 HydrophobicContact CB-CB 4.46Å; L75-T275 HydrophobicContact CD2-CG2 4.44Å
76	S	95.9	Very high	93.6	Very high	3 Å²	3	27.7 Å²	27.7	2%	0.021	15%	0.153	C	C	.	.	H	α-helix	trans	-63.7	-41.3	174.1	-67.1	0	0	0	0	112.7	W67 D72 F73 F80 F336	W67-S76 WeakPolarHBondContact CH2-OG 3.41Å; W67-S76 WeakPolarHBondContact CZ3-OG 3.48Å; D72-S76 WeakPolarHBondContact O-CB 3.05Å; D72-S76 PolarHBondContact O-N 2.95Å; D72-S76 PolarHBondContact O-OG 2.68Å; F73-S76 PolarHBondContact O-N 2.73Å; F73-S76 VanDerWaalsContact O-N 3.16Å; S76-F80 WeakPolarHBondContact O-CB 3.32Å; S76-F80 PolarHBondContact O-N 3.32Å; S76-F336 WeakPolarHBondContact O-CE2 3.45Å
77	V	96.3	Very high	93.5	Very high	0 Å²	0	25.2 Å²	25.2	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-70.8	-40.9	177.1	-174.9	0	0	0	0	110.9	F73 L74 F80 A81 F118 L333 F336 T353	F73-V77 HydrophobicContact CD2-CG2 3.8Å; F73-V77 HydrophobicContact CE1-CG2 4.34Å; F73-V77 HydrophobicContact CE2-CG2 3.34Å; F73-V77 HydrophobicContact CG-CG2 4.47Å; F73-V77 HydrophobicContact CZ-CG2 3.65Å; F73-V77 WeakPolarHBondContact O-CG2 3.27Å; F73-V77 PolarHBondContact O-N 3.2Å; L74-V77 PolarHBondContact O-N 3.31Å; V77-F80 PolarHBondContact O-N 3.25Å; V77-A81 WeakPolarHBondContact O-CB 3.4Å; V77-A81 PolarHBondContact O-N 2.96Å; V77-F118 HydrophobicContact CG1-CE1 4.34Å; V77-F118 HydrophobicContact CG1-CE2 4.42Å; V77-F118 HydrophobicContact CG1-CZ 3.55Å; V77-L333 HydrophobicContact CG1-CD2 3.76Å; V77-F336 HydrophobicContact CG2-CB 4.39Å; V77-F336 HydrophobicContact CG2-CD2 4.03Å; V77-T353 HydrophobicContact CB-CG2 4.25Å; V77-T353 HydrophobicContact CG1-CG2 3.62Å
78	I	96.1	Very high	93	Very high	15 Å²	15	25.9 Å²	25.9	8%	0.077	14%	0.141	C	C	.	.	H	α-helix	trans	-63.8	-46.5	175.7	-70.9	169.1	0	0	0	111.1	L74 L75 F80 A81 V82 Y278 T353 V356	L74-I78 HydrophobicContact CD1-CD1 4.11Å; L74-I78 HydrophobicContact CD1-CG1 4.5Å; L74-I78 HydrophobicContact CD2-CD1 4.47Å; L74-I78 HydrophobicContact CG-CD1 3.84Å; L74-I78 WeakPolarHBondContact O-CB 3.43Å; L74-I78 VanDerWaalsContact O-CG1 3.25Å; L74-I78 WeakPolarHBondContact O-CG1 3.42Å; L74-I78 PolarHBondContact O-N 2.92Å; L75-I78 PolarHBondContact O-N 3.14Å; I78-F80 VanDerWaalsContact C-N 3.27Å; I78-F80 PolarHBondContact O-N 3.44Å; I78-A81 PolarHBondContact O-N 3.47Å; I78-V82 HydrophobicContact CG2-CG2 4.24Å; I78-V82 WeakPolarHBondContact O-CB 3.47Å; I78-V82 WeakPolarHBondContact O-CG2 3.09Å; I78-V82 PolarHBondContact O-N 3.47Å; I78-Y278 HydrophobicContact CG2-CE2 4.34Å; I78-Y278 WeakPolarHBondContact CG2-OH 3.36Å; I78-T353 HydrophobicContact CB-CG2 4.47Å; I78-T353 HydrophobicContact CG1-CG2 3.69Å; I78-V356 HydrophobicContact CD1-CG1 4.32Å; I78-V356 HydrophobicContact CG1-CG1 4.43Å; I78-V356 HydrophobicContact CG2-CG1 4Å
79	G	94.9	Very high	93.1	Very high	2 Å²	2	25.4 Å²	25.4	2%	0.021	12%	0.119	C	C	.	.	H	α-helix	trans	-66.1	-29.2	178.6	0	0	0	0	0	112.8	L75 D425	L75-G79 PolarHBondContact O-N 3.01Å; G79-D425 VanDerWaalsContact O-CB 3.32Å; G79-D425 WeakPolarHBondContact O-CB 2.87Å
80	F	95.4	Very high	93.1	Very high	18 Å²	18	18.9 Å²	18.9	8%	0.079	9%	0.09	C	C	.	.	H	α-helix	trans	-70	-47.4	170.9	167.9	-110.7	0	0	0	112.3	S76 V77 I78 F330 V332 L333 F336	S76-F80 WeakPolarHBondContact O-CB 3.32Å; S76-F80 PolarHBondContact O-N 3.32Å; V77-F80 PolarHBondContact O-N 3.25Å; I78-F80 VanDerWaalsContact C-N 3.27Å; I78-F80 PolarHBondContact O-N 3.44Å; F80-F330 HydrophobicContact CZ-CB 4.14Å; F80-F330 HydrophobicContact CZ-CD2 4.36Å; F80-F330 HydrophobicContact CZ-CG 4.46Å; F80-V332 HydrophobicContact CB-CG1 4.44Å; F80-V332 HydrophobicContact CD1-CB 4.13Å; F80-V332 HydrophobicContact CD1-CG1 3.76Å; F80-V332 HydrophobicContact CD2-CB 4.32Å; F80-V332 HydrophobicContact CD2-CG1 3.79Å; F80-V332 HydrophobicContact CD2-CG2 4.25Å; F80-V332 HydrophobicContact CE1-CB 3.72Å; F80-V332 HydrophobicContact CE1-CG1 3.89Å; F80-V332 HydrophobicContact CE1-CG2 4.22Å; F80-V332 HydrophobicContact CE2-CB 3.96Å; F80-V332 HydrophobicContact CE2-CG1 3.96Å; F80-V332 HydrophobicContact CE2-CG2 3.62Å; F80-V332 HydrophobicContact CG-CB 4.41Å; F80-V332 HydrophobicContact CG-CG1 3.7Å; F80-V332 HydrophobicContact CZ-CB 3.64Å; F80-V332 HydrophobicContact CZ-CG1 4Å; F80-V332 HydrophobicContact CZ-CG2 3.59Å; F80-L333 HydrophobicContact CD1-CD2 4.24Å; F80-L333 HydrophobicContact CE1-CD2 4.3Å; F80-F336 HydrophobicContact CB-CE2 4.06Å
81	A	94.5	Very high	93.1	Very high	1 Å²	1	14.3 Å²	14.3	1%	0.008	7%	0.071	C	C	.	.	H	α-helix	trans	-72.3	-32.7	-177.8	0	0	0	0	0	113	V77 I78 D83 N86 S325 T353 N357	V77-A81 WeakPolarHBondContact O-CB 3.4Å; V77-A81 PolarHBondContact O-N 2.96Å; I78-A81 PolarHBondContact O-N 3.47Å; A81-D83 PolarHBondContact O-N 2.87Å; A81-N86 PolarHBondContact O-OD1 3.36Å; A81-S325 CarbonylContact C-O 3.49Å; A81-T353 HydrophobicContact CB-CG2 4.48Å; A81-N357 HydrophobicContact CB-CB 4.33Å; A81-N357 PolarHBondContact O-OD1 3.33Å; A81-N357 VanDerWaalsContact O-OD1 3.04Å
82	V	94.8	Very high	92.9	Very high	6 Å²	6	13 Å²	13	4%	0.036	6%	0.061	C	C	.	.	S	Bend	trans	-93.6	101	177.8	179.3	0	0	0	0	109.3	I78 N86 N357 T360 L422	I78-V82 HydrophobicContact CG2-CG2 4.24Å; I78-V82 WeakPolarHBondContact O-CB 3.47Å; I78-V82 WeakPolarHBondContact O-CG2 3.09Å; I78-V82 PolarHBondContact O-N 3.47Å; V82-N86 WeakPolarHBondContact CA-OD1 3.39Å; V82-N357 HydrophobicContact CG2-CB 4.45Å; V82-T360 HydrophobicContact CG1-CG2 3.6Å; V82-T360 HydrophobicContact CG2-CG2 4.39Å; V82-L422 HydrophobicContact CG1-CD2 3.86Å; V82-L422 WeakPolarHBondContact O-CD2 3.31Å
83	D	92.4	Very high	92.7	Very high	25 Å²	25	12.3 Å²	12.3	13%	0.134	6%	0.058	C	C	.	.	S	Bend	trans	-126.1	-166.8	-173.5	79.2	-12.5	0	0	0	112	A81 A85 N86 S426	A81-D83 PolarHBondContact O-N 2.87Å; D83-A85 PolarHBondContact O-N 3.37Å; D83-A85 VanDerWaalsContact OD1-CA 3.26Å; D83-A85 WeakPolarHBondContact OD1-CA 3.49Å; D83-A85 WeakPolarHBondContact OD1-CB 3.49Å; D83-A85 PolarHBondContact OD1-N 2.89Å; D83-N86 PolarHBondContact N-OD1 3.38Å; D83-N86 PolarHBondContact O-N 2.75Å; D83-N86 PolarHBondContact O-OD1 3.49Å; D83-N86 PolarHBondContact OD1-N 2.82Å; D83-N86 PolarHBondContact OD1-OD1 2.92Å; D83-N86 VanDerWaalsContact OD1-OD1 3.05Å; D83-S426 WeakPolarHBondContact CB-OG 3.43Å
84	L	89.2	Confident	92.6	Very high	2 Å²	2	12.3 Å²	12.3	1%	0.01	6%	0.058	C	C	.	.	H	α-helix	trans	-63.1	-30.4	175.8	-77.6	84.2	0	0	0	112.2	N86 V87 W88 Y160 I163 L419 L422	L84-N86 PolarHBondContact O-N 3Å; L84-V87 PolarHBondContact O-N 3.28Å; L84-W88 VanDerWaalsContact C-CD1 3.4Å; L84-W88 HydrophobicContact CB-CD2 4.13Å; L84-W88 HydrophobicContact CB-CH2 4.45Å; L84-W88 HydrophobicContact CB-CZ2 3.94Å; L84-W88 HydrophobicContact CD2-CE3 4.24Å; L84-W88 HydrophobicContact CD2-CH2 3.94Å; L84-W88 HydrophobicContact CD2-CZ2 4.26Å; L84-W88 HydrophobicContact CD2-CZ3 3.9Å; L84-W88 VanDerWaalsContact O-CG 3.31Å; L84-W88 PolarHBondContact O-N 2.77Å; L84-W88 PolarHBondContact O-NE1 3.13Å; L84-Y160 VanDerWaalsContact CD1-OH 3.28Å; L84-Y160 WeakPolarHBondContact CD1-OH 3.37Å; L84-I163 HydrophobicContact CD2-CG2 3.49Å; L84-I163 VanDerWaalsContact CD2-CG2 3.49Å; L84-L419 HydrophobicContact CD2-CD2 4.26Å; L84-L419 HydrophobicContact CG-CD2 4.34Å; L84-L422 HydrophobicContact CD1-CB 4.09Å
85	A	89.8	Confident	92.3	Very high	8 Å²	8	14 Å²	14	7%	0.066	6%	0.063	C	C	.	.	H	α-helix	trans	-60.2	-33.5	179.1	0	0	0	0	0	112.5	D83 V87 W88 R89 F90	D83-A85 PolarHBondContact O-N 3.37Å; D83-A85 VanDerWaalsContact OD1-CA 3.26Å; D83-A85 WeakPolarHBondContact OD1-CA 3.49Å; D83-A85 WeakPolarHBondContact OD1-CB 3.49Å; D83-A85 PolarHBondContact OD1-N 2.89Å; A85-V87 PolarHBondContact O-N 2.91Å; A85-W88 VanDerWaalsContact CA-CD1 3.46Å; A85-R89 HydrophobicContact CB-CB 4.38Å; A85-R89 WeakPolarHBondContact O-CB 3.35Å; A85-R89 PolarHBondContact O-N 3.12Å; A85-F90 PolarHBondContact O-N 3.25Å
86	N	92.8	Very high	92	Very high	0 Å²	0	15.9 Å²	15.9	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-62	-32.7	172.7	-59.5	80.8	0	0	0	112.3	A81 V82 D83 L84 P91 S325 N357 S361 S364	A81-N86 PolarHBondContact O-OD1 3.36Å; V82-N86 WeakPolarHBondContact CA-OD1 3.39Å; D83-N86 PolarHBondContact N-OD1 3.38Å; D83-N86 PolarHBondContact O-N 2.75Å; D83-N86 PolarHBondContact O-OD1 3.49Å; D83-N86 PolarHBondContact OD1-N 2.82Å; D83-N86 PolarHBondContact OD1-OD1 2.92Å; D83-N86 VanDerWaalsContact OD1-OD1 3.05Å; L84-N86 PolarHBondContact O-N 3Å; N86-P91 WeakPolarHBondContact O-CD 3.47Å; N86-S325 PolarHBondContact ND2-OG 3.24Å; N86-N357 PolarHBondContact ND2-O 3.23Å; N86-N357 PolarHBondContact ND2-OD1 2.96Å; N86-S361 PolarHBondContact ND2-OG 2.95Å; N86-S364 PolarHBondContact O-OG 3.48Å
87	V	88.8	Confident	91.8	Very high	1 Å²	1	16 Å²	16	1%	0.006	7%	0.07	C	C	.	.	H	α-helix	trans	-93.2	-43.2	-173.9	-176	0	0	0	0	111.8	L84 A85 P91 I368 L422	L84-V87 PolarHBondContact O-N 3.28Å; A85-V87 PolarHBondContact O-N 2.91Å; V87-P91 WeakPolarHBondContact O-CD 3.3Å; V87-P91 WeakPolarHBondContact O-CG 3.49Å; V87-I368 HydrophobicContact CG1-CD1 3.69Å; V87-I368 HydrophobicContact CG1-CG1 4.14Å; V87-I368 WeakPolarHBondContact O-CG1 3.2Å; V87-L422 HydrophobicContact CG2-CD1 3.8Å
88	W	83.9	Confident	91.5	Very high	28 Å²	28	16.4 Å²	16.4	11%	0.106	8%	0.075	C	C	.	.	H	α-helix	trans	-104.7	-12.8	-169.8	70	-0.3	0	0	0	116	L84 A85 I163 A391 L393 V394 F395	L84-W88 VanDerWaalsContact C-CD1 3.4Å; L84-W88 HydrophobicContact CB-CD2 4.13Å; L84-W88 HydrophobicContact CB-CH2 4.45Å; L84-W88 HydrophobicContact CB-CZ2 3.94Å; L84-W88 HydrophobicContact CD2-CE3 4.24Å; L84-W88 HydrophobicContact CD2-CH2 3.94Å; L84-W88 HydrophobicContact CD2-CZ2 4.26Å; L84-W88 HydrophobicContact CD2-CZ3 3.9Å; L84-W88 VanDerWaalsContact O-CG 3.31Å; L84-W88 PolarHBondContact O-N 2.77Å; L84-W88 PolarHBondContact O-NE1 3.13Å; A85-W88 VanDerWaalsContact CA-CD1 3.46Å; W88-I163 HydrophobicContact CH2-CD1 3.64Å; W88-I163 HydrophobicContact CH2-CG1 4.11Å; W88-I163 HydrophobicContact CH2-CG2 3.7Å; W88-I163 HydrophobicContact CZ2-CD1 4.2Å; W88-I163 HydrophobicContact CZ3-CG2 3.98Å; W88-A391 HydrophobicContact CZ3-CB 4.24Å; W88-L393 HydrophobicContact CB-CD2 4.18Å; W88-V394 HydrophobicContact CB-CG2 3.59Å; W88-V394 HydrophobicContact CD2-CG2 4.21Å; W88-V394 HydrophobicContact CE3-CB 3.95Å; W88-V394 HydrophobicContact CE3-CG2 3.57Å; W88-V394 HydrophobicContact CG-CG2 4.28Å; W88-F395 HydrophobicContact CZ3-CE2 4.4Å
89	R	89.6	Confident	91.3	Very high	55 Å²	55	15.8 Å²	15.8	21%	0.208	7%	0.072	C	C	.	.	T	Hydrogen-bonded Turn	trans	-117.3	-52	-170.6	-173.4	177.3	177.9	170	-0.6	110.4	A85 Y92 L93	A85-R89 HydrophobicContact CB-CB 4.38Å; A85-R89 WeakPolarHBondContact O-CB 3.35Å; A85-R89 PolarHBondContact O-N 3.12Å; R89-Y92 PolarHBondContact O-N 3.37Å; R89-L93 HydrophobicContact CG-CD1 3.95Å; R89-L93 HydrophobicContact CG-CG 4.22Å; R89-L93 WeakPolarHBondContact O-CB 3.47Å; R89-L93 WeakPolarHBondContact O-CG 3.49Å; R89-L93 PolarHBondContact O-N 3.25Å
90	F	93.4	Very high	91.2	Very high	1 Å²	1	16.5 Å²	16.5	0%	0.004	8%	0.08	C	C	.	.	H	α-helix	trans	-56.8	-47.5	179	174.8	-92.1	0	0	0	113.4	A85 Y92 L93 C94 F102 L103 Y106 Y301 Q321 S361	A85-F90 PolarHBondContact O-N 3.25Å; F90-Y92 VanDerWaalsContact C-N 3.32Å; F90-Y92 PolarHBondContact O-N 2.61Å; F90-L93 PolarHBondContact O-N 3.43Å; F90-C94 WeakPolarHBondContact CE1-SG 3.33Å; F90-C94 WeakPolarHBondContact CZ-SG 3.5Å; F90-C94 PolarHBondContact O-N 3.15Å; F90-C94 PolarHBondContact O-SG 3.48Å; F90-F102 HydrophobicContact CE2-CE1 4.33Å; F90-L103 HydrophobicContact CZ-CD2 3.91Å; F90-Y106 HydrophobicContact CD2-CD2 4.2Å; F90-Y106 AromaticContact CD2-CE2 3.71Å; F90-Y106 HydrophobicContact CD2-CE2 3.71Å; F90-Y106 AromaticContact CD2-CZ 3.89Å; F90-Y106 AromaticContact CE2-CD1 3.9Å; F90-Y106 HydrophobicContact CE2-CD1 3.9Å; F90-Y106 AromaticContact CE2-CD2 3.78Å; F90-Y106 HydrophobicContact CE2-CD2 3.78Å; F90-Y106 AromaticContact CE2-CE1 3.68Å; F90-Y106 HydrophobicContact CE2-CE1 3.68Å; F90-Y106 AromaticContact CE2-CE2 3.55Å; F90-Y106 HydrophobicContact CE2-CE2 3.55Å; F90-Y106 AromaticContact CE2-CG 3.95Å; F90-Y106 HydrophobicContact CE2-CG 3.95Å; F90-Y106 AromaticContact CE2-CZ 3.5Å; F90-Y106 VanDerWaalsContact CE2-CZ 3.5Å; F90-Y106 HydrophobicContact CZ-CD1 4.49Å; F90-Y106 HydrophobicContact CZ-CE1 4.28Å; F90-Y301 WeakPolarHBondContact CE1-OH 3.21Å; F90-Q321 HydrophobicContact CD2-CG 4.2Å; F90-S361 VanDerWaalsContact CD1-C 3.46Å; F90-S361 WeakPolarHBondContact CD1-O 3.42Å; F90-S361 VanDerWaalsContact CE1-C 3.46Å; F90-S361 VanDerWaalsContact CE1-O 3.24Å; F90-S361 WeakPolarHBondContact CE1-O 3.34Å
91	P	92.3	Very high	91.2	Very high	0 Å²	0	15.7 Å²	15.7	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-61.9	-42.4	179.6	-27.1	39.6	0	0	0	112.2	N86 V87 C94 Y95 I368 F369	N86-P91 WeakPolarHBondContact O-CD 3.47Å; V87-P91 WeakPolarHBondContact O-CD 3.3Å; V87-P91 WeakPolarHBondContact O-CG 3.49Å; P91-C94 WeakPolarHBondContact O-CB 3.45Å; P91-C94 PolarHBondContact O-N 3.44Å; P91-Y95 PolarHBondContact O-N 3.24Å; P91-Y95 VanDerWaalsContact O-N 3.1Å; P91-I368 HydrophobicContact CB-CB 4.31Å; P91-I368 HydrophobicContact CB-CG2 3.82Å; P91-I368 HydrophobicContact CG-CB 4.39Å; P91-I368 HydrophobicContact CG-CG1 4.26Å; P91-I368 HydrophobicContact CG-CG2 4.34Å; P91-F369 HydrophobicContact CB-CD2 3.94Å; P91-F369 HydrophobicContact CB-CE2 3.57Å; P91-F369 VanDerWaalsContact O-CE2 3.26Å; P91-F369 WeakPolarHBondContact O-CE2 3.38Å
92	Y	89.1	Confident	91.2	Very high	44 Å²	44	15.7 Å²	15.7	17%	0.173	8%	0.076	C	C	.	.	H	α-helix	trans	-62.2	-45.7	176.6	172.2	-94.3	0	0	0	111.9	R89 F90 C94 Y95 K96 A387 T388 E389	R89-Y92 PolarHBondContact O-N 3.37Å; F90-Y92 VanDerWaalsContact C-N 3.32Å; F90-Y92 PolarHBondContact O-N 2.61Å; Y92-C94 VanDerWaalsContact C-N 3.33Å; Y92-C94 PolarHBondContact O-N 2.84Å; Y92-Y95 WeakPolarHBondContact O-CB 3.43Å; Y92-Y95 PolarHBondContact O-N 3.09Å; Y92-Y95 VanDerWaalsContact O-N 3.16Å; Y92-K96 HydrophobicContact CE1-CB 4.26Å; Y92-K96 HydrophobicContact CE1-CD 3.91Å; Y92-K96 WeakPolarHBondContact O-CB 3.36Å; Y92-K96 PolarHBondContact O-N 3.46Å; Y92-A387 WeakPolarHBondContact CE2-O 3.5Å; Y92-T388 WeakPolarHBondContact CD2-O 3.45Å; Y92-E389 HydrophobicContact CD1-CB 3.44Å; Y92-E389 VanDerWaalsContact CD1-CB 3.44Å; Y92-E389 HydrophobicContact CD1-CG 4.41Å; Y92-E389 HydrophobicContact CD2-CB 4.06Å; Y92-E389 HydrophobicContact CE1-CB 3.48Å; Y92-E389 VanDerWaalsContact CE1-CB 3.48Å; Y92-E389 HydrophobicContact CE1-CG 3.99Å; Y92-E389 WeakPolarHBondContact CE1-OE2 3.46Å; Y92-E389 HydrophobicContact CE2-CB 4.1Å; Y92-E389 HydrophobicContact CG-CB 3.72Å
93	L	91.1	Very high	91.2	Very high	3 Å²	3	17.4 Å²	17.4	2%	0.016	9%	0.085	C	C	.	.	H	α-helix	trans	-62.6	-40.1	178.2	-72.8	-179.9	0	0	0	112	R89 F90 Y95 N97 F102 D317 Q321	R89-L93 HydrophobicContact CG-CD1 3.95Å; R89-L93 HydrophobicContact CG-CG 4.22Å; R89-L93 WeakPolarHBondContact O-CB 3.47Å; R89-L93 WeakPolarHBondContact O-CG 3.49Å; R89-L93 PolarHBondContact O-N 3.25Å; F90-L93 PolarHBondContact O-N 3.43Å; L93-Y95 VanDerWaalsContact C-N 3.34Å; L93-Y95 PolarHBondContact O-N 2.9Å; L93-N97 WeakPolarHBondContact O-CB 3.33Å; L93-N97 PolarHBondContact O-N 2.75Å; L93-N97 PolarHBondContact O-ND2 3.35Å; L93-F102 HydrophobicContact CB-CE1 4.1Å; L93-F102 HydrophobicContact CB-CZ 3.95Å; L93-D317 HydrophobicContact CD2-CB 4.15Å; L93-Q321 HydrophobicContact CD1-CB 3.8Å; L93-Q321 HydrophobicContact CD1-CG 4Å
94	C	92.5	Very high	91.3	Very high	1 Å²	1	20.4 Å²	20.4	1%	0.007	10%	0.1	C	C	.	.	H	α-helix	trans	-56	-53.1	172.6	-67	0	0	0	0	109.8	F90 P91 Y92 N97 G99 F102 Y301	F90-C94 WeakPolarHBondContact CE1-SG 3.33Å; F90-C94 WeakPolarHBondContact CZ-SG 3.5Å; F90-C94 PolarHBondContact O-N 3.15Å; F90-C94 PolarHBondContact O-SG 3.48Å; P91-C94 WeakPolarHBondContact O-CB 3.45Å; P91-C94 PolarHBondContact O-N 3.44Å; Y92-C94 VanDerWaalsContact C-N 3.33Å; Y92-C94 PolarHBondContact O-N 2.84Å; C94-N97 PolarHBondContact O-N 3.07Å; C94-G99 WeakPolarHBondContact O-CA 3.28Å; C94-G99 PolarHBondContact O-N 3.42Å; C94-F102 HydrophobicContact CB-CD1 4.23Å; C94-F102 VanDerWaalsContact SG-CD1 3.6Å; C94-Y301 HydrophobicContact CB-CD2 3.99Å; C94-Y301 HydrophobicContact CB-CE2 3.48Å; C94-Y301 VanDerWaalsContact CB-CE2 3.48Å
95	Y	90.2	Very high	91.5	Very high	57 Å²	57	20.3 Å²	20.3	22%	0.224	10%	0.099	C	C	.	.	H	α-helix	trans	-59.9	-50.5	-179.2	175.5	-106.6	0	0	0	113.5	P91 Y92 L93 N97 A300 F369 Q384 A387	P91-Y95 PolarHBondContact O-N 3.24Å; P91-Y95 VanDerWaalsContact O-N 3.1Å; Y92-Y95 WeakPolarHBondContact O-CB 3.43Å; Y92-Y95 PolarHBondContact O-N 3.09Å; Y92-Y95 VanDerWaalsContact O-N 3.16Å; L93-Y95 VanDerWaalsContact C-N 3.34Å; L93-Y95 PolarHBondContact O-N 2.9Å; Y95-N97 VanDerWaalsContact C-N 3.26Å; Y95-N97 PolarHBondContact O-N 3.39Å; Y95-A300 HydrophobicContact CD2-CB 4.16Å; Y95-A300 WeakPolarHBondContact CD2-O 3.42Å; Y95-A300 HydrophobicContact CE2-CB 3.83Å; Y95-F369 HydrophobicContact CD1-CE1 4.5Å; Y95-F369 HydrophobicContact CD1-CZ 4.43Å; Y95-F369 AromaticContact CD2-CE1 3.8Å; Y95-F369 HydrophobicContact CD2-CE1 3.8Å; Y95-F369 HydrophobicContact CD2-CZ 4.23Å; Y95-F369 AromaticContact CG-CE1 3.76Å; Y95-F369 HydrophobicContact CG-CE1 3.76Å; Y95-F369 AromaticContact CG-CZ 3.75Å; Y95-F369 HydrophobicContact CG-CZ 3.75Å; Y95-Q384 HydrophobicContact CE1-CB 4.31Å; Y95-Q384 VanDerWaalsContact OH-CA 3.3Å; Y95-Q384 WeakPolarHBondContact OH-CA 3.39Å; Y95-Q384 WeakPolarHBondContact OH-CB 3.39Å; Y95-Q384 PolarHBondContact OH-N 3.12Å; Y95-A387 HydrophobicContact CD1-CB 3.95Å; Y95-A387 HydrophobicContact CE1-CB 3.95Å
96	K	89.6	Confident	91.7	Very high	63 Å²	63	20.3 Å²	20.3	27%	0.274	10%	0.098	S	C	.	.	H	α-helix	trans	-56.9	-40	178.7	-179.6	-167.8	168.5	-158.3	0	111.9	Y92 E313 D317	Y92-K96 HydrophobicContact CE1-CB 4.26Å; Y92-K96 HydrophobicContact CE1-CD 3.91Å; Y92-K96 WeakPolarHBondContact O-CB 3.36Å; Y92-K96 PolarHBondContact O-N 3.46Å; K96-E313 IonicContact NZ-OE1 3.31Å; K96-E313 PolarHBondContact NZ-OE1 3.23Å; K96-D317 IonicContact NZ-OD2 2.77Å; K96-D317 PolarHBondContact NZ-OD2 3.44Å
97	N	92.1	Very high	91.8	Very high	6 Å²	6	23.7 Å²	23.7	3%	0.032	12%	0.119	C	C	.	.	T	Hydrogen-bonded Turn	trans	-101.7	28.9	-167.8	-65	-32.3	0	0	0	114	L93 C94 Y95 F102 V314 D317	L93-N97 WeakPolarHBondContact O-CB 3.33Å; L93-N97 PolarHBondContact O-N 2.75Å; L93-N97 PolarHBondContact O-ND2 3.35Å; C94-N97 PolarHBondContact O-N 3.07Å; Y95-N97 VanDerWaalsContact C-N 3.26Å; Y95-N97 PolarHBondContact O-N 3.39Å; N97-F102 HydrophobicContact CB-CB 4.22Å; N97-F102 HydrophobicContact CB-CD2 3.44Å; N97-F102 VanDerWaalsContact CB-CD2 3.44Å; N97-F102 HydrophobicContact CB-CE2 4.05Å; N97-F102 HydrophobicContact CB-CG 4.08Å; N97-V314 HydrophobicContact CB-CB 4.35Å; N97-V314 HydrophobicContact CB-CG1 3.89Å; N97-V314 HydrophobicContact CB-CG2 3.85Å; N97-D317 WeakPolarHBondContact ND2-CB 3.23Å; N97-D317 PolarHBondContact ND2-OD2 3.44Å
98	G	90.2	Very high	92	Very high	9 Å²	9	27.3 Å²	27.3	9%	0.093	14%	0.137	C	C	.	.	T	Hydrogen-bonded Turn	trans	93.7	29.9	173.3	0	0	0	0	0	114.5	G100 A101 N303 D305	G98-G100 PolarHBondContact O-N 3.39Å; G98-A101 VanDerWaalsContact O-CB 3.26Å; G98-A101 WeakPolarHBondContact O-CB 3.36Å; G98-A101 PolarHBondContact O-N 2.92Å; G98-N303 CarbonylContact C-O 3.6Å; G98-D305 PolarHBondContact O-N 2.96Å
99	G	91.6	Very high	92.3	Very high	2 Å²	2	26.2 Å²	26.2	2%	0.021	13%	0.133	C	C	.	.	B	Isolated β-bridge	trans	53.5	-115.6	174.9	0	0	0	0	0	113	C94 A101 F102 Y301 N303	C94-G99 WeakPolarHBondContact O-CA 3.28Å; C94-G99 PolarHBondContact O-N 3.42Å; G99-A101 PolarHBondContact O-N 2.97Å; G99-F102 WeakPolarHBondContact O-CB 3.35Å; G99-F102 PolarHBondContact O-N 3.43Å; G99-Y301 CarbonylContact C-O 3.03Å; G99-Y301 WeakPolarHBondContact CA-O 3.22Å; G99-N303 CarbonylContact C-O 3.56Å; G99-N303 WeakPolarHBondContact CA-O 3.1Å
100	G	92.5	Very high	92.6	Very high	17 Å²	17	24.4 Å²	24.4	18%	0.175	13%	0.128	C	C	.	.	G	3₁₀ helix	trans	-62.4	-25.3	-179.8	0	0	0	0	0	113.7	G98 F102 L103 N303	G98-G100 PolarHBondContact O-N 3.39Å; G100-F102 VanDerWaalsContact C-N 3.27Å; G100-F102 PolarHBondContact O-N 3.34Å; G100-L103 WeakPolarHBondContact O-CB 3.49Å; G100-L103 PolarHBondContact O-N 3.47Å; G100-N303 PolarHBondContact N-O 3.33Å
101	A	94.4	Very high	92.6	Very high	1 Å²	1	27.2 Å²	27.2	1%	0.008	15%	0.145	C	C	.	.	G	3₁₀ helix	trans	-64.9	-31.5	177.8	0	0	0	0	0	112.2	G98 G99 L103 I104 P105 I304 F306 L309	G98-A101 VanDerWaalsContact O-CB 3.26Å; G98-A101 WeakPolarHBondContact O-CB 3.36Å; G98-A101 PolarHBondContact O-N 2.92Å; G99-A101 PolarHBondContact O-N 2.97Å; A101-L103 PolarHBondContact O-N 3.08Å; A101-I104 WeakPolarHBondContact O-CB 3.05Å; A101-I104 PolarHBondContact O-N 2.94Å; A101-I104 VanDerWaalsContact O-N 3.14Å; A101-P105 WeakPolarHBondContact O-CD 3.4Å; A101-I304 HydrophobicContact CB-CG2 4.28Å; A101-F306 HydrophobicContact CB-CD1 4.43Å; A101-L309 HydrophobicContact CB-CD1 4.35Å; A101-L309 HydrophobicContact CB-CD2 4.36Å; A101-L309 HydrophobicContact CB-CG 4.28Å
102	F	94.9	Very high	92.6	Very high	0 Å²	0	28.9 Å²	28.9	0%	0	15%	0.154	C	C	.	.	G	3₁₀ helix	trans	-62.3	-23.4	178	-179.1	-106.2	0	0	0	113.4	F90 L93 C94 N97 G99 G100 I104 P105 Y106 V314 D317 A318	F90-F102 HydrophobicContact CE2-CE1 4.33Å; L93-F102 HydrophobicContact CB-CE1 4.1Å; L93-F102 HydrophobicContact CB-CZ 3.95Å; C94-F102 HydrophobicContact CB-CD1 4.23Å; C94-F102 VanDerWaalsContact SG-CD1 3.6Å; N97-F102 HydrophobicContact CB-CB 4.22Å; N97-F102 HydrophobicContact CB-CD2 3.44Å; N97-F102 VanDerWaalsContact CB-CD2 3.44Å; N97-F102 HydrophobicContact CB-CE2 4.05Å; N97-F102 HydrophobicContact CB-CG 4.08Å; G99-F102 WeakPolarHBondContact O-CB 3.35Å; G99-F102 PolarHBondContact O-N 3.43Å; G100-F102 VanDerWaalsContact C-N 3.27Å; G100-F102 PolarHBondContact O-N 3.34Å; F102-I104 PolarHBondContact O-N 3.45Å; F102-P105 HydrophobicContact CD2-CG 4.38Å; F102-P105 WeakPolarHBondContact O-CD 3.27Å; F102-P105 VanDerWaalsContact O-CG 3.26Å; F102-P105 WeakPolarHBondContact O-CG 3.2Å; F102-Y106 HydrophobicContact CE1-CD2 4.22Å; F102-Y106 VanDerWaalsContact O-CB 3.29Å; F102-Y106 WeakPolarHBondContact O-CB 3.48Å; F102-Y106 PolarHBondContact O-N 3.06Å; F102-Y106 VanDerWaalsContact O-N 3.13Å; F102-V314 HydrophobicContact CD2-CG1 3.97Å; F102-V314 HydrophobicContact CE2-CG1 4.49Å; F102-D317 HydrophobicContact CE2-CB 4.42Å; F102-A318 HydrophobicContact CD2-CB 4.4Å; F102-A318 HydrophobicContact CE2-CB 3.57Å; F102-A318 HydrophobicContact CZ-CB 3.8Å
103	L	94.3	Very high	92.6	Very high	43 Å²	43	26.8 Å²	26.8	23%	0.225	15%	0.145	C	C	.	.	H	α-helix	trans	-64.9	-23.3	177.4	-60.7	178	0	0	0	112.5	F90 G100 A101 T107 F362	F90-L103 HydrophobicContact CZ-CD2 3.91Å; G100-L103 WeakPolarHBondContact O-CB 3.49Å; G100-L103 PolarHBondContact O-N 3.47Å; A101-L103 PolarHBondContact O-N 3.08Å; L103-T107 WeakPolarHBondContact O-CB 3.44Å; L103-T107 PolarHBondContact O-N 2.62Å; L103-T107 PolarHBondContact O-OG1 3.11Å; L103-F362 HydrophobicContact CD1-CD2 4.39Å; L103-F362 HydrophobicContact CD1-CE2 3.88Å; L103-F362 HydrophobicContact CD2-CD2 4.36Å
104	I	94.6	Very high	92.8	Very high	88 Å²	88	26.7 Å²	26.7	45%	0.451	15%	0.145	S	C	.	.	H	α-helix	trans	-65.9	-62.2	176.9	-60.9	171.1	0	0	0	110.9	A101 F102 Y106 T107 L108 F306 L309	A101-I104 WeakPolarHBondContact O-CB 3.05Å; A101-I104 PolarHBondContact O-N 2.94Å; A101-I104 VanDerWaalsContact O-N 3.14Å; F102-I104 PolarHBondContact O-N 3.45Å; I104-Y106 VanDerWaalsContact C-N 3.27Å; I104-Y106 PolarHBondContact O-N 3.02Å; I104-T107 PolarHBondContact O-N 3.28Å; I104-L108 WeakPolarHBondContact O-CB 3.49Å; I104-L108 PolarHBondContact O-N 3.01Å; I104-F306 HydrophobicContact CD1-CE1 3.91Å; I104-L309 HydrophobicContact CD1-CD1 4.25Å
105	P	93.8	Very high	92.9	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-61.7	-36.7	177.2	24.5	-34.2	0	0	0	111.8	A101 F102 L108 F109 L309 V314 W315 A318	A101-P105 WeakPolarHBondContact O-CD 3.4Å; F102-P105 HydrophobicContact CD2-CG 4.38Å; F102-P105 WeakPolarHBondContact O-CD 3.27Å; F102-P105 VanDerWaalsContact O-CG 3.26Å; F102-P105 WeakPolarHBondContact O-CG 3.2Å; P105-L108 PolarHBondContact O-N 3.18Å; P105-F109 HydrophobicContact CB-CE2 4.18Å; P105-F109 WeakPolarHBondContact O-CB 3.38Å; P105-F109 WeakPolarHBondContact O-CD2 3.13Å; P105-F109 VanDerWaalsContact O-CG 3.26Å; P105-F109 WeakPolarHBondContact O-CG 3.32Å; P105-F109 PolarHBondContact O-N 3.2Å; P105-L309 HydrophobicContact CG-CD2 4.01Å; P105-V314 HydrophobicContact CG-CG1 4.14Å; P105-W315 HydrophobicContact CB-CD2 3.99Å; P105-W315 HydrophobicContact CB-CE3 3.51Å; P105-W315 HydrophobicContact CB-CH2 4.28Å; P105-W315 HydrophobicContact CB-CZ3 3.68Å; P105-A318 HydrophobicContact CB-CB 3.92Å; P105-A318 HydrophobicContact CG-CB 4.24Å
106	Y	93.9	Very high	93.2	Very high	7 Å²	7	24.9 Å²	24.9	3%	0.027	14%	0.138	C	C	.	.	H	α-helix	trans	-60.3	-49.6	177.2	-177.5	-98.6	0	0	0	112.7	F90 F102 I104 F109 L110 Q321 I322 C358	F90-Y106 HydrophobicContact CD2-CD2 4.2Å; F90-Y106 AromaticContact CD2-CE2 3.71Å; F90-Y106 HydrophobicContact CD2-CE2 3.71Å; F90-Y106 AromaticContact CD2-CZ 3.89Å; F90-Y106 AromaticContact CE2-CD1 3.9Å; F90-Y106 HydrophobicContact CE2-CD1 3.9Å; F90-Y106 AromaticContact CE2-CD2 3.78Å; F90-Y106 HydrophobicContact CE2-CD2 3.78Å; F90-Y106 AromaticContact CE2-CE1 3.68Å; F90-Y106 HydrophobicContact CE2-CE1 3.68Å; F90-Y106 AromaticContact CE2-CE2 3.55Å; F90-Y106 HydrophobicContact CE2-CE2 3.55Å; F90-Y106 AromaticContact CE2-CG 3.95Å; F90-Y106 HydrophobicContact CE2-CG 3.95Å; F90-Y106 AromaticContact CE2-CZ 3.5Å; F90-Y106 VanDerWaalsContact CE2-CZ 3.5Å; F90-Y106 HydrophobicContact CZ-CD1 4.49Å; F90-Y106 HydrophobicContact CZ-CE1 4.28Å; F102-Y106 HydrophobicContact CE1-CD2 4.22Å; F102-Y106 VanDerWaalsContact O-CB 3.29Å; F102-Y106 WeakPolarHBondContact O-CB 3.48Å; F102-Y106 PolarHBondContact O-N 3.06Å; F102-Y106 VanDerWaalsContact O-N 3.13Å; I104-Y106 VanDerWaalsContact C-N 3.27Å; I104-Y106 PolarHBondContact O-N 3.02Å; Y106-F109 PolarHBondContact O-N 3.36Å; Y106-L110 PolarHBondContact O-N 3.37Å; Y106-Q321 HydrophobicContact CD2-CG 4.49Å; Y106-Q321 HydrophobicContact CE2-CG 3.98Å; Y106-I322 HydrophobicContact CD1-CD1 4.22Å; Y106-I322 HydrophobicContact CD2-CD1 3.6Å; Y106-I322 HydrophobicContact CD2-CG1 3.74Å; Y106-I322 HydrophobicContact CE1-CD1 3.89Å; Y106-I322 HydrophobicContact CE2-CD1 3.2Å; Y106-I322 HydrophobicContact CE2-CG1 3.69Å; Y106-I322 HydrophobicContact CG-CD1 4.1Å; Y106-I322 HydrophobicContact CG-CG1 4.43Å; Y106-C358 HydrophobicContact CE1-CB 4.22Å; Y106-C358 PolarHBondContact OH-SG 2.86Å; Y106-C358 VanDerWaalsContact OH-SG 3.37Å
107	T	94.3	Very high	93.4	Very high	72 Å²	72	21.9 Å²	21.9	44%	0.442	13%	0.125	S	C	.	.	H	α-helix	trans	-69.1	-37.3	179	-54.5	0	0	0	0	111.4	L103 I104 F109 L110 V111	L103-T107 WeakPolarHBondContact O-CB 3.44Å; L103-T107 PolarHBondContact O-N 2.62Å; L103-T107 PolarHBondContact O-OG1 3.11Å; I104-T107 PolarHBondContact O-N 3.28Å; T107-F109 VanDerWaalsContact C-N 3.34Å; T107-F109 PolarHBondContact O-N 2.95Å; T107-L110 WeakPolarHBondContact O-CB 3.31Å; T107-L110 PolarHBondContact O-N 3.46Å; T107-V111 HydrophobicContact CG2-CG2 4.5Å; T107-V111 WeakPolarHBondContact O-CG2 3.1Å; T107-V111 PolarHBondContact O-N 2.86Å
108	L	93.6	Very high	93.6	Very high	76 Å²	76	21.6 Å²	21.6	40%	0.398	12%	0.124	S	C	.	.	H	α-helix	trans	-58.1	-49.6	174.5	-176.2	71.1	0	0	0	110.3	I104 P105 L110 V111 I112 W315	I104-L108 WeakPolarHBondContact O-CB 3.49Å; I104-L108 PolarHBondContact O-N 3.01Å; P105-L108 PolarHBondContact O-N 3.18Å; L108-L110 PolarHBondContact O-N 2.97Å; L108-V111 PolarHBondContact O-N 3.43Å; L108-I112 HydrophobicContact CD1-CG2 4.03Å; L108-I112 HydrophobicContact CG-CD1 4.25Å; L108-I112 HydrophobicContact CG-CG2 4.38Å; L108-I112 WeakPolarHBondContact O-CG1 3.18Å; L108-I112 WeakPolarHBondContact O-CG2 3.18Å; L108-I112 PolarHBondContact O-N 3.15Å; L108-W315 HydrophobicContact CD2-CH2 4.46Å; L108-W315 HydrophobicContact CD2-CZ3 3.77Å
109	F	91.5	Very high	93.9	Very high	6 Å²	6	21.2 Å²	21.2	3%	0.026	12%	0.119	C	C	.	.	H	α-helix	trans	-67.7	-33.9	-179.9	-65.2	-34	0	0	0	114	P105 Y106 T107 V111 I112 A113 G114 W315 A318 A319 I322 F535	P105-F109 HydrophobicContact CB-CE2 4.18Å; P105-F109 WeakPolarHBondContact O-CB 3.38Å; P105-F109 WeakPolarHBondContact O-CD2 3.13Å; P105-F109 VanDerWaalsContact O-CG 3.26Å; P105-F109 WeakPolarHBondContact O-CG 3.32Å; P105-F109 PolarHBondContact O-N 3.2Å; Y106-F109 PolarHBondContact O-N 3.36Å; T107-F109 VanDerWaalsContact C-N 3.34Å; T107-F109 PolarHBondContact O-N 2.95Å; F109-V111 VanDerWaalsContact C-N 3.32Å; F109-V111 PolarHBondContact O-N 3.39Å; F109-I112 HydrophobicContact CD1-CD1 3.92Å; F109-I112 HydrophobicContact CD1-CG1 4.3Å; F109-I112 HydrophobicContact CE1-CD1 4.29Å; F109-A113 PolarHBondContact O-N 3.26Å; F109-A113 VanDerWaalsContact O-N 3.08Å; F109-G114 PolarHBondContact O-N 3.08Å; F109-W315 HydrophobicContact CE1-CE3 4.21Å; F109-W315 HydrophobicContact CE2-CB 4.24Å; F109-W315 AromaticContact CE2-CE3 3.91Å; F109-W315 HydrophobicContact CE2-CE3 3.91Å; F109-W315 WeakPolarHBondContact CE2-O 3.36Å; F109-W315 HydrophobicContact CZ-CB 4.13Å; F109-W315 HydrophobicContact CZ-CD2 4.39Å; F109-W315 AromaticContact CZ-CE3 3.48Å; F109-W315 HydrophobicContact CZ-CE3 3.48Å; F109-W315 VanDerWaalsContact CZ-CE3 3.48Å; F109-W315 HydrophobicContact CZ-CZ3 4.29Å; F109-A318 HydrophobicContact CD2-CB 3.64Å; F109-A318 HydrophobicContact CE2-CB 3.79Å; F109-A319 HydrophobicContact CD2-CB 3.97Å; F109-A319 HydrophobicContact CE2-CB 3.98Å; F109-A319 HydrophobicContact CG-CB 4.48Å; F109-A319 HydrophobicContact CZ-CB 4.47Å; F109-I322 HydrophobicContact CB-CG1 4.14Å; F109-F535 HydrophobicContact CD1-CD1 4.43Å; F109-F535 HydrophobicContact CD1-CD2 4.41Å; F109-F535 AromaticContact CD1-CE1 3.67Å; F109-F535 HydrophobicContact CD1-CE1 3.67Å; F109-F535 AromaticContact CD1-CE2 3.7Å; F109-F535 HydrophobicContact CD1-CE2 3.7Å; F109-F535 AromaticContact CD1-CZ 3.25Å; F109-F535 HydrophobicContact CD1-CZ 3.25Å; F109-F535 HydrophobicContact CD2-CZ 4.22Å; F109-F535 AromaticContact CE1-CD2 3.85Å; F109-F535 HydrophobicContact CE1-CD2 3.85Å; F109-F535 AromaticContact CE1-CE1 3.84Å; F109-F535 HydrophobicContact CE1-CE1 3.84Å; F109-F535 AromaticContact CE1-CE2 2.97Å; F109-F535 HydrophobicContact CE1-CE2 2.97Å; F109-F535 AromaticContact CE1-CZ 2.95Å; F109-F535 HydrophobicContact CE1-CZ 2.95Å; F109-F535 HydrophobicContact CE2-CE2 4.45Å; F109-F535 AromaticContact CE2-CZ 3.95Å; F109-F535 HydrophobicContact CE2-CZ 3.95Å; F109-F535 HydrophobicContact CG-CE1 4.21Å; F109-F535 AromaticContact CG-CZ 3.89Å; F109-F535 HydrophobicContact CG-CZ 3.89Å; F109-F535 HydrophobicContact CZ-CE1 4.41Å; F109-F535 AromaticContact CZ-CE2 3.38Å; F109-F535 HydrophobicContact CZ-CE2 3.38Å; F109-F535 AromaticContact CZ-CZ 3.26Å; F109-F535 HydrophobicContact CZ-CZ 3.26Å
110	L	93.9	Very high	94.2	Very high	16 Å²	16	21.1 Å²	21.1	8%	0.084	12%	0.119	C	C	.	.	I	π-helix	trans	-56.6	-49.1	169.6	178.5	63.7	0	0	0	111.1	Y106 T107 L108 M115 I322 L326 C358	Y106-L110 PolarHBondContact O-N 3.37Å; T107-L110 WeakPolarHBondContact O-CB 3.31Å; T107-L110 PolarHBondContact O-N 3.46Å; L108-L110 PolarHBondContact O-N 2.97Å; L110-M115 HydrophobicContact CD1-CB 4.47Å; L110-M115 HydrophobicContact CD1-CE 4.49Å; L110-M115 HydrophobicContact CD2-CE 4.49Å; L110-M115 HydrophobicContact CG-CE 4.26Å; L110-M115 VanDerWaalsContact O-CB 3.25Å; L110-M115 WeakPolarHBondContact O-CB 3.23Å; L110-M115 PolarHBondContact O-N 3.44Å; L110-I322 HydrophobicContact CB-CD1 3.84Å; L110-I322 HydrophobicContact CD1-CD1 4.26Å; L110-L326 HydrophobicContact CD1-CD1 3.92Å; L110-C358 HydrophobicContact CD2-CB 4.23Å; L110-C358 WeakPolarHBondContact CD2-SG 3.48Å
111	V	94.2	Very high	94.3	Very high	61 Å²	61	20.3 Å²	20.3	37%	0.37	11%	0.11	S	C	.	.	I	π-helix	trans	-70.4	-53.7	-176	172.1	0	0	0	0	110.1	T107 L108 F109 P116 Y523	T107-V111 HydrophobicContact CG2-CG2 4.5Å; T107-V111 WeakPolarHBondContact O-CG2 3.1Å; T107-V111 PolarHBondContact O-N 2.86Å; L108-V111 PolarHBondContact O-N 3.43Å; F109-V111 VanDerWaalsContact C-N 3.32Å; F109-V111 PolarHBondContact O-N 3.39Å; V111-P116 WeakPolarHBondContact O-CD 3.38Å; V111-P116 VanDerWaalsContact O-CG 3.23Å; V111-P116 WeakPolarHBondContact O-CG 3.06Å; V111-Y523 VanDerWaalsContact C-OH 3.24Å; V111-Y523 HydrophobicContact CG1-CE2 4.4Å; V111-Y523 WeakPolarHBondContact CG1-OH 3.49Å; V111-Y523 PolarHBondContact O-OH 3.21Å
112	I	91.5	Very high	94.4	Very high	35 Å²	35	20.3 Å²	20.3	18%	0.179	11%	0.11	C	C	.	.	I	π-helix	trans	-76.7	-28.6	-169.6	72.4	178.8	0	0	0	114.5	L108 F109 V531 S532 F535	L108-I112 HydrophobicContact CD1-CG2 4.03Å; L108-I112 HydrophobicContact CG-CD1 4.25Å; L108-I112 HydrophobicContact CG-CG2 4.38Å; L108-I112 WeakPolarHBondContact O-CG1 3.18Å; L108-I112 WeakPolarHBondContact O-CG2 3.18Å; L108-I112 PolarHBondContact O-N 3.15Å; F109-I112 HydrophobicContact CD1-CD1 3.92Å; F109-I112 HydrophobicContact CD1-CG1 4.3Å; F109-I112 HydrophobicContact CE1-CD1 4.29Å; I112-V531 HydrophobicContact CB-CG1 3.88Å; I112-V531 HydrophobicContact CD1-CG1 4.33Å; I112-V531 HydrophobicContact CG1-CG1 4.44Å; I112-V531 HydrophobicContact CG2-CG1 4.47Å; I112-S532 PolarHBondContact O-OG 2.52Å; I112-F535 HydrophobicContact CD1-CG 4.48Å
113	A	90.8	Very high	94.5	Very high	0 Å²	0	20.3 Å²	20.3	0%	0	11%	0.11	C	C	.	.	I	π-helix	trans	-130.9	-54	-171	0	0	0	0	0	113.2	F109 P116 L117 F323 F535	F109-A113 PolarHBondContact O-N 3.26Å; F109-A113 VanDerWaalsContact O-N 3.08Å; A113-P116 WeakPolarHBondContact O-CD 3.37Å; A113-L117 HydrophobicContact CB-CD1 4.45Å; A113-L117 WeakPolarHBondContact O-CB 3.32Å; A113-L117 WeakPolarHBondContact O-CD1 3.27Å; A113-L117 VanDerWaalsContact O-CG 3.23Å; A113-L117 WeakPolarHBondContact O-CG 3.49Å; A113-L117 PolarHBondContact O-N 2.89Å; A113-F323 HydrophobicContact CB-CZ 3.95Å; A113-F535 HydrophobicContact CB-CD1 3.98Å; A113-F535 HydrophobicContact CB-CE1 4.45Å
114	G	93.5	Very high	94.6	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	10%	0.1	C	C	.	.	I	π-helix	trans	-57.5	-59.8	-174	0	0	0	0	0	113.2	F109 L117 F118	F109-G114 PolarHBondContact O-N 3.08Å; G114-L117 PolarHBondContact O-N 3.16Å; G114-F118 VanDerWaalsContact O-CB 3.22Å; G114-F118 WeakPolarHBondContact O-CB 3.03Å; G114-F118 PolarHBondContact O-N 2.79Å
115	M	95.3	Very high	94.6	Very high	20 Å²	20	14.1 Å²	14.1	10%	0.099	8%	0.078	C	C	.	.	H	α-helix	trans	-66.3	-41.3	-178	-169.6	-173.2	-58.7	0	0	112.8	L110 Y119 L351 W524	L110-M115 HydrophobicContact CD1-CB 4.47Å; L110-M115 HydrophobicContact CD1-CE 4.49Å; L110-M115 HydrophobicContact CD2-CE 4.49Å; L110-M115 HydrophobicContact CG-CE 4.26Å; L110-M115 VanDerWaalsContact O-CB 3.25Å; L110-M115 WeakPolarHBondContact O-CB 3.23Å; L110-M115 PolarHBondContact O-N 3.44Å; M115-Y119 WeakPolarHBondContact O-CB 3.34Å; M115-Y119 PolarHBondContact O-N 3.11Å; M115-L351 HydrophobicContact CE-CD1 3.87Å; M115-L351 HydrophobicContact SD-CD1 3.53Å; M115-L351 VanDerWaalsContact SD-CD1 3.53Å; M115-W524 HydrophobicContact CG-CH2 3.89Å; M115-W524 HydrophobicContact CG-CZ3 4.19Å; M115-W524 HydrophobicContact SD-CH2 3.81Å
116	P	95.9	Very high	94.7	Very high	0 Å²	0	14.1 Å²	14.1	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-57.8	-48.5	172.3	-28.8	36.5	0	0	0	113.2	V111 A113 Y119 M120 W524 C527 W528	V111-P116 WeakPolarHBondContact O-CD 3.38Å; V111-P116 VanDerWaalsContact O-CG 3.23Å; V111-P116 WeakPolarHBondContact O-CG 3.06Å; A113-P116 WeakPolarHBondContact O-CD 3.37Å; P116-Y119 PolarHBondContact O-N 2.77Å; P116-M120 WeakPolarHBondContact O-CB 3.23Å; P116-M120 PolarHBondContact O-N 2.76Å; P116-W524 HydrophobicContact CB-CE3 4.04Å; P116-W524 HydrophobicContact CB-CZ3 4.14Å; P116-W524 HydrophobicContact CG-CE3 4.04Å; P116-W524 HydrophobicContact CG-CZ3 3.86Å; P116-C527 HydrophobicContact CB-CB 3.78Å; P116-C527 HydrophobicContact CG-CB 3.73Å; P116-W528 VanDerWaalsContact C-NE1 3.33Å; P116-W528 PolarHBondContact O-NE1 3.39Å
117	L	95.3	Very high	94.8	Very high	0 Å²	0	16 Å²	16	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-70.9	-37.3	-177	-66.7	167	0	0	0	111.7	A113 G114 Y119 M120 E121 F323 V492 A496 L536	A113-L117 HydrophobicContact CB-CD1 4.45Å; A113-L117 WeakPolarHBondContact O-CB 3.32Å; A113-L117 WeakPolarHBondContact O-CD1 3.27Å; A113-L117 VanDerWaalsContact O-CG 3.23Å; A113-L117 WeakPolarHBondContact O-CG 3.49Å; A113-L117 PolarHBondContact O-N 2.89Å; G114-L117 PolarHBondContact O-N 3.16Å; L117-Y119 VanDerWaalsContact C-N 3.34Å; L117-Y119 PolarHBondContact O-N 2.97Å; L117-M120 HydrophobicContact CD2-CE 3.63Å; L117-M120 HydrophobicContact CD2-SD 4.29Å; L117-M120 WeakPolarHBondContact O-CB 3.37Å; L117-M120 PolarHBondContact O-N 3.09Å; L117-E121 PolarHBondContact O-N 3.15Å; L117-F323 HydrophobicContact CD1-CE1 3.52Å; L117-F323 HydrophobicContact CD1-CZ 3.75Å; L117-V492 HydrophobicContact CB-CG1 4.49Å; L117-V492 HydrophobicContact CD1-CG1 3.69Å; L117-V492 HydrophobicContact CD2-CG1 4.27Å; L117-V492 HydrophobicContact CG-CG1 4.37Å; L117-A496 HydrophobicContact CD2-CB 3.76Å; L117-L536 HydrophobicContact CD1-CD1 3.68Å
118	F	96	Very high	94.8	Very high	0 Å²	0	14.7 Å²	14.7	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-58.1	-45.5	171	-169.3	-87.2	0	0	0	112	V77 G114 L122 L326 L333 A350 T353	V77-F118 HydrophobicContact CG1-CE1 4.34Å; V77-F118 HydrophobicContact CG1-CE2 4.42Å; V77-F118 HydrophobicContact CG1-CZ 3.55Å; G114-F118 VanDerWaalsContact O-CB 3.22Å; G114-F118 WeakPolarHBondContact O-CB 3.03Å; G114-F118 PolarHBondContact O-N 2.79Å; F118-L122 HydrophobicContact CD1-CD1 3.76Å; F118-L122 HydrophobicContact CD1-CG 4.36Å; F118-L122 HydrophobicContact CE1-CD1 3.38Å; F118-L122 HydrophobicContact CE1-CG 4.18Å; F118-L122 HydrophobicContact CZ-CD1 4.26Å; F118-L122 WeakPolarHBondContact O-CG 3.32Å; F118-L122 PolarHBondContact O-N 3.44Å; F118-L326 HydrophobicContact CD2-CB 3.93Å; F118-L326 HydrophobicContact CD2-CD2 4.35Å; F118-L326 HydrophobicContact CE2-CB 4.41Å; F118-L326 VanDerWaalsContact CE2-O 3.28Å; F118-L326 WeakPolarHBondContact CE2-O 3.17Å; F118-L333 HydrophobicContact CB-CD1 4.48Å; F118-L333 HydrophobicContact CD2-CD1 3.22Å; F118-L333 HydrophobicContact CD2-CD2 4.19Å; F118-L333 HydrophobicContact CD2-CG 4.33Å; F118-L333 HydrophobicContact CE2-CD1 3.41Å; F118-L333 VanDerWaalsContact CE2-CD1 3.41Å; F118-L333 HydrophobicContact CE2-CD2 3.45Å; F118-L333 VanDerWaalsContact CE2-CD2 3.45Å; F118-L333 HydrophobicContact CE2-CG 4.06Å; F118-L333 HydrophobicContact CG-CD1 3.85Å; F118-L333 HydrophobicContact CZ-CD1 4.15Å; F118-L333 HydrophobicContact CZ-CD2 3.66Å; F118-A350 HydrophobicContact CD1-CB 4.02Å; F118-A350 HydrophobicContact CE1-CB 4.39Å; F118-T353 HydrophobicContact CE1-CG2 4.44Å; F118-T353 HydrophobicContact CZ-CG2 3.89Å
119	Y	96.8	Very high	94.8	Very high	1 Å²	1	14.2 Å²	14.2	0%	0.004	7%	0.069	C	C	.	.	H	α-helix	trans	-65.6	-39.4	176.2	176.4	-142.3	0	0	0	112.1	M115 P116 L117 L122 A123 Y347 A350 I512 M516 W524 W528	M115-Y119 WeakPolarHBondContact O-CB 3.34Å; M115-Y119 PolarHBondContact O-N 3.11Å; P116-Y119 PolarHBondContact O-N 2.77Å; L117-Y119 VanDerWaalsContact C-N 3.34Å; L117-Y119 PolarHBondContact O-N 2.97Å; Y119-L122 PolarHBondContact O-N 3.49Å; Y119-A123 HydrophobicContact CE2-CB 4.23Å; Y119-A123 WeakPolarHBondContact O-CB 3.34Å; Y119-A123 PolarHBondContact O-N 3.27Å; Y119-Y347 HydrophobicContact CD1-CD2 4.38Å; Y119-Y347 AromaticContact CE1-CD2 3.97Å; Y119-Y347 HydrophobicContact CE1-CD2 3.97Å; Y119-Y347 HydrophobicContact CE2-CD2 4.33Å; Y119-Y347 AromaticContact CZ-CD2 3.95Å; Y119-A350 HydrophobicContact CD2-CB 3.96Å; Y119-A350 HydrophobicContact CG-CB 4.24Å; Y119-I512 WeakPolarHBondContact OH-CG2 3.49Å; Y119-M516 HydrophobicContact CE2-CE 4.36Å; Y119-M516 WeakPolarHBondContact OH-CE 3.34Å; Y119-W524 AromaticContact CD1-CD2 3.94Å; Y119-W524 HydrophobicContact CD1-CD2 3.94Å; Y119-W524 AromaticContact CD1-CE3 3.82Å; Y119-W524 HydrophobicContact CD1-CE3 3.82Å; Y119-W524 HydrophobicContact CD1-CG 4.42Å; Y119-W524 HydrophobicContact CD1-CZ3 4.19Å; Y119-W524 HydrophobicContact CE1-CD2 4.29Å; Y119-W524 HydrophobicContact CE1-CG 4.37Å; Y119-W528 AromaticContact CD1-CH2 3.92Å; Y119-W528 HydrophobicContact CD1-CH2 3.92Å; Y119-W528 AromaticContact CD1-CZ2 3.41Å; Y119-W528 HydrophobicContact CD1-CZ2 3.41Å; Y119-W528 VanDerWaalsContact CD1-CZ2 3.41Å; Y119-W528 AromaticContact CE1-CH2 3.66Å; Y119-W528 HydrophobicContact CE1-CH2 3.66Å; Y119-W528 AromaticContact CE1-CZ2 3.68Å; Y119-W528 HydrophobicContact CE1-CZ2 3.68Å; Y119-W528 HydrophobicContact CG-CZ2 4.19Å
120	M	96.4	Very high	94.7	Very high	1 Å²	1	16.1 Å²	16.1	1%	0.005	8%	0.078	C	C	.	.	H	α-helix	trans	-58.3	-50.3	176.4	-173.1	-177.8	70.1	0	0	111.3	P116 L117 L122 A123 L124 E495 A496 V499 F508 W528	P116-M120 WeakPolarHBondContact O-CB 3.23Å; P116-M120 PolarHBondContact O-N 2.76Å; L117-M120 HydrophobicContact CD2-CE 3.63Å; L117-M120 HydrophobicContact CD2-SD 4.29Å; L117-M120 WeakPolarHBondContact O-CB 3.37Å; L117-M120 PolarHBondContact O-N 3.09Å; M120-L122 PolarHBondContact O-N 3.4Å; M120-A123 PolarHBondContact O-N 2.94Å; M120-L124 WeakPolarHBondContact O-CB 3.31Å; M120-L124 PolarHBondContact O-N 3.24Å; M120-E495 HydrophobicContact CE-CG 3.9Å; M120-A496 HydrophobicContact CE-CB 4.35Å; M120-V499 HydrophobicContact CG-CG1 4.11Å; M120-V499 HydrophobicContact SD-CB 3.93Å; M120-V499 HydrophobicContact SD-CG1 3.96Å; M120-V499 HydrophobicContact SD-CG2 4.32Å; M120-F508 HydrophobicContact CG-CE1 3.95Å; M120-F508 HydrophobicContact CG-CZ 3.97Å; M120-W528 HydrophobicContact CB-CZ2 4.38Å
121	E	96.1	Very high	94.7	Very high	0 Å²	0	15.3 Å²	15.3	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-62.3	-43.2	179.4	-84.1	-175	-135.5	0	0	112.9	L117 L124 G125 G329 L333 I334 E495	L117-E121 PolarHBondContact O-N 3.15Å; E121-L124 PolarHBondContact O-N 3.33Å; E121-G125 PolarHBondContact O-N 3.4Å; E121-G329 WeakPolarHBondContact OE1-CA 3.31Å; E121-G329 PolarHBondContact OE1-N 3.2Å; E121-L333 HydrophobicContact CB-CB 3.9Å; E121-L333 HydrophobicContact CB-CD1 4.23Å; E121-I334 HydrophobicContact CB-CG1 3.98Å; E121-I334 HydrophobicContact CG-CD1 4.2Å; E121-I334 HydrophobicContact CG-CG1 3.93Å; E121-E495 WeakPolarHBondContact CG-OE1 3.46Å
122	L	96.3	Very high	94.6	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-64	-41.7	177.7	-74.7	-177.7	0	0	0	112.2	F73 F118 Y119 M120 Q126 L333 S337 A350	F73-L122 HydrophobicContact CE2-CD2 4.38Å; F73-L122 HydrophobicContact CZ-CD2 3.97Å; F118-L122 HydrophobicContact CD1-CD1 3.76Å; F118-L122 HydrophobicContact CD1-CG 4.36Å; F118-L122 HydrophobicContact CE1-CD1 3.38Å; F118-L122 HydrophobicContact CE1-CG 4.18Å; F118-L122 HydrophobicContact CZ-CD1 4.26Å; F118-L122 WeakPolarHBondContact O-CG 3.32Å; F118-L122 PolarHBondContact O-N 3.44Å; Y119-L122 PolarHBondContact O-N 3.49Å; M120-L122 PolarHBondContact O-N 3.4Å; L122-Q126 VanDerWaalsContact O-CB 3.25Å; L122-Q126 WeakPolarHBondContact O-CB 3.44Å; L122-Q126 PolarHBondContact O-N 3.12Å; L122-Q126 VanDerWaalsContact O-N 3.11Å; L122-L333 HydrophobicContact CD2-CB 3.93Å; L122-L333 HydrophobicContact CD2-CD2 4.3Å; L122-L333 HydrophobicContact CG-CB 4.35Å; L122-S337 VanDerWaalsContact O-CB 3.24Å; L122-S337 WeakPolarHBondContact O-CB 3.46Å; L122-S337 PolarHBondContact O-OG 3.27Å; L122-A350 HydrophobicContact CD1-CB 3.88Å
123	A	96.8	Very high	94.6	Very high	0 Å²	0	10.8 Å²	10.8	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-68.2	-42.2	176.2	0	0	0	0	0	111.4	Y119 M120 Q126 Y127 F508 I512 M515	Y119-A123 HydrophobicContact CE2-CB 4.23Å; Y119-A123 WeakPolarHBondContact O-CB 3.34Å; Y119-A123 PolarHBondContact O-N 3.27Å; M120-A123 PolarHBondContact O-N 2.94Å; A123-Q126 PolarHBondContact O-N 3.08Å; A123-Y127 WeakPolarHBondContact O-CB 3.12Å; A123-Y127 PolarHBondContact O-N 3.42Å; A123-F508 HydrophobicContact CB-CE2 4.41Å; A123-F508 HydrophobicContact CB-CZ 3.79Å; A123-I512 HydrophobicContact CB-CD1 3.99Å; A123-I512 HydrophobicContact CB-CG1 3.99Å; A123-M515 HydrophobicContact CB-CE 4.26Å
124	L	95.8	Very high	94.7	Very high	1 Å²	1	10.9 Å²	10.9	1%	0.005	5%	0.048	C	C	.	.	H	α-helix	trans	-62.6	-45.9	-179.8	-176.3	69.2	0	0	0	111.9	M120 E121 N128 V135 I138 I334 V499 F508	M120-L124 WeakPolarHBondContact O-CB 3.31Å; M120-L124 PolarHBondContact O-N 3.24Å; E121-L124 PolarHBondContact O-N 3.33Å; L124-N128 WeakPolarHBondContact CD1-ND2 3.46Å; L124-N128 PolarHBondContact O-N 3.37Å; L124-N128 PolarHBondContact O-ND2 2.85Å; L124-V135 HydrophobicContact CD1-CG2 4.09Å; L124-V135 HydrophobicContact CD2-CG1 4.41Å; L124-V135 HydrophobicContact CD2-CG2 4.03Å; L124-V135 HydrophobicContact CG-CG2 3.64Å; L124-I138 HydrophobicContact CD1-CD1 3.81Å; L124-I334 HydrophobicContact CD2-CD1 4.35Å; L124-V499 HydrophobicContact CD1-CG2 4.44Å; L124-V499 HydrophobicContact CD2-CG2 4.01Å; L124-F508 HydrophobicContact CB-CE2 4.19Å; L124-F508 HydrophobicContact CB-CZ 4.46Å; L124-F508 HydrophobicContact CD1-CE2 4.21Å
125	G	95.4	Very high	94.7	Very high	0 Å²	0	10.9 Å²	10.9	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-68.8	-41.7	177.1	0	0	0	0	0	112.9	E121 Y127 R129 S337 S338	E121-G125 PolarHBondContact O-N 3.4Å; G125-Y127 PolarHBondContact O-N 3.5Å; G125-R129 WeakPolarHBondContact O-CA 3.4Å; G125-R129 PolarHBondContact O-N 3.1Å; G125-S337 VanDerWaalsContact CA-OG 3.28Å; G125-S337 WeakPolarHBondContact CA-OG 3.49Å; G125-S338 VanDerWaalsContact O-CA 3.3Å; G125-S338 WeakPolarHBondContact O-CA 3.22Å
126	Q	96.3	Very high	94.7	Very high	0 Å²	0	10 Å²	10	0%	0	4%	0.044	C	C	.	.	H	α-helix	trans	-64.8	-40.6	179.1	-173.1	174.3	-70.6	0	0	113	L122 A123 R129 S337 N340 F342 N344 M515	L122-Q126 VanDerWaalsContact O-CB 3.25Å; L122-Q126 WeakPolarHBondContact O-CB 3.44Å; L122-Q126 PolarHBondContact O-N 3.12Å; L122-Q126 VanDerWaalsContact O-N 3.11Å; A123-Q126 PolarHBondContact O-N 3.08Å; Q126-R129 WeakPolarHBondContact O-CG 3.26Å; Q126-S337 WeakPolarHBondContact CA-O 3.43Å; Q126-S337 PolarHBondContact N-OG 3.25Å; Q126-N340 HydrophobicContact CG-CB 3.99Å; Q126-N340 PolarHBondContact OE1-ND2 3.41Å; Q126-F342 PolarHBondContact NE2-O 3.25Å; Q126-F342 VanDerWaalsContact NE2-O 3.16Å; Q126-N344 PolarHBondContact NE2-O 3.27Å; Q126-N344 PolarHBondContact OE1-ND2 2.88Å; Q126-M515 HydrophobicContact CB-SD 4.18Å; Q126-M515 HydrophobicContact CG-SD 4.06Å
127	Y	95.5	Very high	94.5	Very high	48 Å²	48	13.7 Å²	13.7	19%	0.188	6%	0.06	C	C	.	.	H	α-helix	trans	-67.4	-51.9	-179.4	-174.3	-109.6	0	0	0	111.8	A123 G125 F342 D511 R514 M515	A123-Y127 WeakPolarHBondContact O-CB 3.12Å; A123-Y127 PolarHBondContact O-N 3.42Å; G125-Y127 PolarHBondContact O-N 3.5Å; Y127-F342 AromaticContact CD2-CE2 3.62Å; Y127-F342 HydrophobicContact CD2-CE2 3.62Å; Y127-F342 AromaticContact CD2-CZ 3.86Å; Y127-F342 HydrophobicContact CD2-CZ 3.86Å; Y127-F342 AromaticContact CE2-CE2 3.91Å; Y127-F342 HydrophobicContact CE2-CE2 3.91Å; Y127-F342 AromaticContact CE2-CZ 3.81Å; Y127-F342 HydrophobicContact CE2-CZ 3.81Å; Y127-D511 HydrophobicContact CD1-CB 3.97Å; Y127-D511 HydrophobicContact CD2-CB 3.83Å; Y127-D511 HydrophobicContact CE1-CB 3.75Å; Y127-D511 WeakPolarHBondContact CE1-OD1 3.44Å; Y127-D511 HydrophobicContact CE2-CB 3.63Å; Y127-D511 HydrophobicContact CG-CB 3.99Å; Y127-D511 PolarHBondContact OH-OD1 2.95Å; Y127-R514 PolarHBondContact OH-NH1 3.26Å; Y127-M515 VanDerWaalsContact CA-SD 3.51Å; Y127-M515 VanDerWaalsContact CB-SD 3.59Å; Y127-M515 HydrophobicContact CD2-CE 4.18Å; Y127-M515 HydrophobicContact CD2-CG 3.76Å; Y127-M515 HydrophobicContact CD2-SD 3.91Å; Y127-M515 HydrophobicContact CG-CE 4.39Å; Y127-M515 HydrophobicContact CG-SD 4.26Å
128	N	93.6	Very high	94.3	Very high	44 Å²	44	13.8 Å²	13.8	24%	0.235	6%	0.061	C	C	.	.	H	α-helix	trans	-79.4	-20.2	-173.6	-67.3	-67	0	0	0	113	L124 E130 V135	L124-N128 WeakPolarHBondContact CD1-ND2 3.46Å; L124-N128 PolarHBondContact O-N 3.37Å; L124-N128 PolarHBondContact O-ND2 2.85Å; N128-E130 PolarHBondContact O-N 3.33Å; N128-V135 HydrophobicContact CB-CG2 3.84Å
129	R	93.2	Very high	94.2	Very high	66 Å²	66	13.8 Å²	13.8	25%	0.249	6%	0.061	C	C	.	.	T	Hydrogen-bonded Turn	trans	53	39.5	-177.9	-56.4	-178.8	66.5	77	3.1	112.9	R64 G125 Q126 N340	R64-R129 VanDerWaalsContact CD-O 3.25Å; R64-R129 WeakPolarHBondContact CD-O 2.75Å; R64-R129 VanDerWaalsContact CZ-O 3.27Å; R64-R129 PolarHBondContact NE-O 3.46Å; R64-R129 PolarHBondContact NH1-O 2.69Å; G125-R129 WeakPolarHBondContact O-CA 3.4Å; G125-R129 PolarHBondContact O-N 3.1Å; Q126-R129 WeakPolarHBondContact O-CG 3.26Å; R129-N340 PolarHBondContact NH1-O 2.87Å
130	E	91.1	Very high	93.9	Very high	45 Å²	45	14 Å²	14	21%	0.21	6%	0.062	C	C	.	.			trans	-135.8	155.5	-176.3	-78	-170.1	177.5	0	0	111	N128 T134 K137 S338	N128-E130 PolarHBondContact O-N 3.33Å; E130-T134 WeakPolarHBondContact CB-OG1 3.31Å; E130-T134 VanDerWaalsContact OE2-CB 3.25Å; E130-T134 WeakPolarHBondContact OE2-CB 3.46Å; E130-K137 VanDerWaalsContact CD-NZ 3.31Å; E130-K137 IonicContact OE1-NZ 3.28Å; E130-K137 PolarHBondContact OE1-NZ 3.28Å; E130-K137 WeakPolarHBondContact OE2-CD 3.47Å; E130-K137 WeakPolarHBondContact OE2-CE 3.16Å; E130-K137 IonicContact OE2-NZ 3.11Å; E130-K137 PolarHBondContact OE2-NZ 3.39Å; E130-K137 VanDerWaalsContact OE2-NZ 3.16Å; E130-S338 WeakPolarHBondContact O-CB 3.17Å
131	G	92.1	Very high	93.8	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	7%	0.07	C	C	.	.			trans	-72.3	173.7	176.4	0	0	0	0	0	113.8	A133 T134 V135 D440	G131-A133 VanDerWaalsContact C-N 3.27Å; G131-A133 PolarHBondContact O-N 2.97Å; G131-A133 VanDerWaalsContact O-N 3.1Å; G131-T134 PolarHBondContact N-OG1 3.49Å; G131-T134 PolarHBondContact O-N 3.23Å; G131-T134 VanDerWaalsContact O-N 3.17Å; G131-T134 PolarHBondContact O-OG1 2.96Å; G131-V135 WeakPolarHBondContact O-CB 3.45Å; G131-V135 PolarHBondContact O-N 2.61Å; G131-D440 PolarHBondContact N-OD2 3.15Å
132	A	92.1	Very high	93.7	Very high	1 Å²	1	16.9 Å²	16.9	1%	0.008	8%	0.076	C	C	.	.	T	Hydrogen-bonded Turn	trans	-57.6	-29.3	-170.4	0	0	0	0	0	115.5	V135 W136 G146	A132-V135 WeakPolarHBondContact O-CG1 3.18Å; A132-W136 PolarHBondContact O-NE1 2.85Å; A132-G146 WeakPolarHBondContact O-CA 3.49Å
133	A	92.5	Very high	93.6	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	8%	0.082	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.2	-42.9	175.8	0	0	0	0	0	113.2	G131 K143 Y147 I150	G131-A133 VanDerWaalsContact C-N 3.27Å; G131-A133 PolarHBondContact O-N 2.97Å; G131-A133 VanDerWaalsContact O-N 3.1Å; A133-K143 VanDerWaalsContact O-CG 3.24Å; A133-K143 WeakPolarHBondContact O-CG 3.39Å; A133-Y147 HydrophobicContact CB-CD1 4.43Å; A133-Y147 HydrophobicContact CB-CE1 4.23Å; A133-I150 HydrophobicContact CB-CD1 3.76Å
134	T	92.7	Very high	93.5	Very high	2 Å²	2	18.3 Å²	18.3	1%	0.012	8%	0.082	C	C	.	.	G	3₁₀ helix	trans	-79.2	-26.5	-174.2	43.9	0	0	0	0	112.5	E130 G131 W136 K137 D440 D441	E130-T134 WeakPolarHBondContact CB-OG1 3.31Å; E130-T134 VanDerWaalsContact OE2-CB 3.25Å; E130-T134 WeakPolarHBondContact OE2-CB 3.46Å; G131-T134 PolarHBondContact N-OG1 3.49Å; G131-T134 PolarHBondContact O-N 3.23Å; G131-T134 VanDerWaalsContact O-N 3.17Å; G131-T134 PolarHBondContact O-OG1 2.96Å; T134-W136 PolarHBondContact O-N 3.05Å; T134-K137 WeakPolarHBondContact O-CG 3.31Å; T134-K137 PolarHBondContact O-N 3.43Å; T134-D440 HydrophobicContact CG2-CB 4.01Å; T134-D440 WeakPolarHBondContact OG1-CB 3.43Å; T134-D441 HydrophobicContact CG2-CB 3.76Å
135	V	94.4	Very high	93.5	Very high	0 Å²	0	18.2 Å²	18.2	0%	0	8%	0.082	C	C	.	.	G	3₁₀ helix	trans	-52.3	-30.1	174.4	77.7	0	0	0	0	113.2	L124 N128 G131 A132 K137 I138 I334	L124-V135 HydrophobicContact CD1-CG2 4.09Å; L124-V135 HydrophobicContact CD2-CG1 4.41Å; L124-V135 HydrophobicContact CD2-CG2 4.03Å; L124-V135 HydrophobicContact CG-CG2 3.64Å; N128-V135 HydrophobicContact CB-CG2 3.84Å; G131-V135 WeakPolarHBondContact O-CB 3.45Å; G131-V135 PolarHBondContact O-N 2.61Å; A132-V135 WeakPolarHBondContact O-CG1 3.18Å; V135-K137 PolarHBondContact O-N 2.92Å; V135-I138 WeakPolarHBondContact O-CG1 3.19Å; V135-I138 PolarHBondContact O-N 2.79Å; V135-I334 HydrophobicContact CB-CG2 4.28Å; V135-I334 HydrophobicContact CG1-CD1 4.46Å; V135-I334 HydrophobicContact CG1-CG2 4.29Å; V135-I334 HydrophobicContact CG2-CG2 4.31Å
136	W	94.8	Very high	93.5	Very high	2 Å²	2	18.3 Å²	18.3	1%	0.008	8%	0.082	C	C	.	.	G	3₁₀ helix	trans	-70.1	6.5	177.9	-70.4	103.7	0	0	0	115.1	A132 T134 I138 C139 F142 K143 V145 E495 V499	A132-W136 PolarHBondContact O-NE1 2.85Å; T134-W136 PolarHBondContact O-N 3.05Å; W136-I138 HydrophobicContact CE3-CD1 4.42Å; W136-I138 HydrophobicContact CE3-CG1 4.26Å; W136-I138 HydrophobicContact CZ3-CD1 4.37Å; W136-I138 PolarHBondContact O-N 2.78Å; W136-I138 VanDerWaalsContact O-N 3.11Å; W136-C139 CarbonylContact O-C 3.55Å; W136-C139 PolarHBondContact O-N 3.06Å; W136-C139 VanDerWaalsContact O-O 3.08Å; W136-F142 HydrophobicContact CD2-CB 4.08Å; W136-F142 HydrophobicContact CE3-CB 3.43Å; W136-F142 VanDerWaalsContact CE3-CB 3.43Å; W136-F142 HydrophobicContact CH2-CB 4.38Å; W136-F142 HydrophobicContact CZ3-CB 3.6Å; W136-F142 HydrophobicContact CZ3-CG 4.33Å; W136-K143 VanDerWaalsContact CB-CA 3.49Å; W136-K143 HydrophobicContact CB-CB 4.06Å; W136-K143 HydrophobicContact CB-CG 4.04Å; W136-V145 HydrophobicContact CD2-CB 4.45Å; W136-V145 HydrophobicContact CH2-CB 4.49Å; W136-V145 HydrophobicContact CH2-CG1 4.41Å; W136-V145 HydrophobicContact CZ2-CB 3.68Å; W136-V145 HydrophobicContact CZ2-CG1 3.48Å; W136-V145 VanDerWaalsContact CZ2-CG1 3.48Å; W136-V145 HydrophobicContact CZ2-CG2 4.2Å; W136-E495 HydrophobicContact CH2-CB 4.24Å; W136-E495 HydrophobicContact CH2-CG 4.01Å; W136-E495 HydrophobicContact CZ2-CB 4.05Å; W136-E495 HydrophobicContact CZ2-CG 3.79Å; W136-V499 HydrophobicContact CH2-CG2 4.26Å
137	K	90.8	Very high	93.4	Very high	76 Å²	76	20 Å²	20	33%	0.33	9%	0.089	S	C	.	.	G	3₁₀ helix	trans	-55.8	-19.1	160.4	-71.5	176.1	-168.7	167.4	0	112.7	E130 T134 V135 C139 P601 E602	E130-K137 VanDerWaalsContact CD-NZ 3.31Å; E130-K137 IonicContact OE1-NZ 3.28Å; E130-K137 PolarHBondContact OE1-NZ 3.28Å; E130-K137 WeakPolarHBondContact OE2-CD 3.47Å; E130-K137 WeakPolarHBondContact OE2-CE 3.16Å; E130-K137 IonicContact OE2-NZ 3.11Å; E130-K137 PolarHBondContact OE2-NZ 3.39Å; E130-K137 VanDerWaalsContact OE2-NZ 3.16Å; T134-K137 WeakPolarHBondContact O-CG 3.31Å; T134-K137 PolarHBondContact O-N 3.43Å; V135-K137 PolarHBondContact O-N 2.92Å; K137-C139 VanDerWaalsContact C-N 3.27Å; K137-C139 PolarHBondContact O-N 3.47Å; K137-P601 CarbonylContact O-C 3.59Å; K137-P601 VanDerWaalsContact O-CA 3.24Å; K137-P601 WeakPolarHBondContact O-CA 3.25Å; K137-E602 HydrophobicContact CB-CG 4.28Å; K137-E602 HydrophobicContact CG-CG 4.38Å; K137-E602 WeakPolarHBondContact CG-OE2 3.46Å; K137-E602 PolarHBondContact O-N 2.98Å
138	I	92.4	Very high	93.4	Very high	3 Å²	3	17.7 Å²	17.7	2%	0.015	8%	0.08	C	C	.	.	G	3₁₀ helix	trans	-62.7	-30.3	169	63.2	158.3	0	0	0	113.3	L124 V135 W136 V499 Y503 P601	L124-I138 HydrophobicContact CD1-CD1 3.81Å; V135-I138 WeakPolarHBondContact O-CG1 3.19Å; V135-I138 PolarHBondContact O-N 2.79Å; W136-I138 HydrophobicContact CE3-CD1 4.42Å; W136-I138 HydrophobicContact CE3-CG1 4.26Å; W136-I138 HydrophobicContact CZ3-CD1 4.37Å; W136-I138 PolarHBondContact O-N 2.78Å; W136-I138 VanDerWaalsContact O-N 3.11Å; I138-V499 HydrophobicContact CD1-CG2 4.17Å; I138-Y503 HydrophobicContact CB-CD2 3.62Å; I138-Y503 HydrophobicContact CB-CE2 3.76Å; I138-Y503 HydrophobicContact CB-CG 4.19Å; I138-Y503 HydrophobicContact CD1-CD1 4.45Å; I138-Y503 HydrophobicContact CD1-CD2 4.4Å; I138-Y503 HydrophobicContact CD1-CG 4.09Å; I138-Y503 HydrophobicContact CG2-CD2 4.24Å; I138-Y503 HydrophobicContact CG2-CE2 3.89Å; I138-P601 WeakPolarHBondContact O-CA 3.36Å; I138-P601 VanDerWaalsContact O-CG 3.27Å; I138-P601 WeakPolarHBondContact O-CG 3.25Å
139	C	92.5	Very high	93.5	Very high	0 Å²	0	15.8 Å²	15.8	0%	0	7%	0.069	C	C	.	.	S	Bend	trans	-154.9	88.5	179.4	-164.7	0	0	0	0	109.4	W136 K137 I141 F142	W136-C139 CarbonylContact O-C 3.55Å; W136-C139 PolarHBondContact O-N 3.06Å; W136-C139 VanDerWaalsContact O-O 3.08Å; K137-C139 VanDerWaalsContact C-N 3.27Å; K137-C139 PolarHBondContact O-N 3.47Å; C139-I141 PolarHBondContact O-N 3Å; C139-F142 HydrophobicContact CB-CD2 4.16Å; C139-F142 PolarHBondContact O-N 3.3Å; C139-F142 VanDerWaalsContact SG-CD2 3.55Å
140	P	91.9	Very high	93.5	Very high	4 Å²	4	13 Å²	13	3%	0.026	6%	0.06	C	C	.	.	G	3₁₀ helix	trans	-56.1	-27.7	-168.9	-29.6	35.3	0	0	0	115.7	F142 K143 C598 T600 E602	P140-F142 PolarHBondContact O-N 2.88Å; P140-K143 PolarHBondContact O-N 3.41Å; P140-C598 VanDerWaalsContact CD-O 3.31Å; P140-C598 WeakPolarHBondContact CD-O 3.07Å; P140-T600 VanDerWaalsContact CD-O 3.25Å; P140-T600 WeakPolarHBondContact CD-O 3.3Å; P140-E602 HydrophobicContact CG-CG 3.83Å
141	I	93.3	Very high	93.7	Very high	36 Å²	36	11.9 Å²	11.9	19%	0.185	6%	0.056	C	C	.	.	G	3₁₀ helix	trans	-62.8	-30.5	176	-162.8	169.3	0	0	0	112.7	C139 A580 C598	C139-I141 PolarHBondContact O-N 3Å; I141-A580 HydrophobicContact CD1-CB 4.42Å; I141-A580 HydrophobicContact CG1-CB 3.72Å; I141-C598 HydrophobicContact CB-CB 4.14Å; I141-C598 WeakPolarHBondContact CB-O 3.46Å; I141-C598 HydrophobicContact CD1-CB 4.44Å; I141-C598 PolarHBondContact N-O 2.93Å
142	F	94.7	Very high	93.8	Very high	26 Å²	26	11.9 Å²	11.9	11%	0.114	6%	0.056	C	C	.	.	G	3₁₀ helix	trans	-95.2	9.9	-177.5	-69.7	-64.9	0	0	0	113.9	W136 C139 P140 G144 V145 I494 F502	W136-F142 HydrophobicContact CD2-CB 4.08Å; W136-F142 HydrophobicContact CE3-CB 3.43Å; W136-F142 VanDerWaalsContact CE3-CB 3.43Å; W136-F142 HydrophobicContact CH2-CB 4.38Å; W136-F142 HydrophobicContact CZ3-CB 3.6Å; W136-F142 HydrophobicContact CZ3-CG 4.33Å; C139-F142 HydrophobicContact CB-CD2 4.16Å; C139-F142 PolarHBondContact O-N 3.3Å; C139-F142 VanDerWaalsContact SG-CD2 3.55Å; P140-F142 PolarHBondContact O-N 2.88Å; F142-G144 PolarHBondContact O-N 3.37Å; F142-V145 HydrophobicContact CB-CG2 4.11Å; F142-V145 HydrophobicContact CD1-CG2 4.2Å; F142-V145 VanDerWaalsContact O-CB 3.3Å; F142-V145 WeakPolarHBondContact O-CB 3.24Å; F142-V145 WeakPolarHBondContact O-CG2 3.43Å; F142-V145 PolarHBondContact O-N 3.47Å; F142-I494 HydrophobicContact CD1-CG2 3.53Å; F142-I494 HydrophobicContact CE1-CG2 3.6Å; F142-F502 HydrophobicContact CD2-CG 4.46Å; F142-F502 HydrophobicContact CE2-CB 4.06Å; F142-F502 AromaticContact CE2-CD1 3.86Å; F142-F502 HydrophobicContact CE2-CD1 3.86Å; F142-F502 AromaticContact CE2-CD2 3.41Å; F142-F502 HydrophobicContact CE2-CD2 3.41Å; F142-F502 VanDerWaalsContact CE2-CD2 3.41Å; F142-F502 HydrophobicContact CE2-CE1 4.1Å; F142-F502 AromaticContact CE2-CE2 3.68Å; F142-F502 HydrophobicContact CE2-CE2 3.68Å; F142-F502 AromaticContact CE2-CG 3.51Å; F142-F502 HydrophobicContact CE2-CG 3.51Å; F142-F502 HydrophobicContact CE2-CZ 4.01Å; F142-F502 AromaticContact CZ-CD2 3.78Å; F142-F502 HydrophobicContact CZ-CD2 3.78Å; F142-F502 HydrophobicContact CZ-CE1 4.34Å; F142-F502 AromaticContact CZ-CE2 3.56Å; F142-F502 HydrophobicContact CZ-CE2 3.56Å; F142-F502 HydrophobicContact CZ-CG 4.26Å; F142-F502 AromaticContact CZ-CZ 3.86Å; F142-F502 HydrophobicContact CZ-CZ 3.86Å
143	K	94.6	Very high	93.9	Very high	30 Å²	30	12.1 Å²	12.1	13%	0.13	6%	0.058	C	C	.	.	H	α-helix	trans	-55.7	-25.4	175	-152.6	-166.9	-177.4	-172.2	0	113.2	A133 W136 P140 V145 G146 Y147 D441 Y579	A133-K143 VanDerWaalsContact O-CG 3.24Å; A133-K143 WeakPolarHBondContact O-CG 3.39Å; W136-K143 VanDerWaalsContact CB-CA 3.49Å; W136-K143 HydrophobicContact CB-CB 4.06Å; W136-K143 HydrophobicContact CB-CG 4.04Å; P140-K143 PolarHBondContact O-N 3.41Å; K143-V145 PolarHBondContact O-N 2.93Å; K143-G146 PolarHBondContact O-N 3.47Å; K143-Y147 HydrophobicContact CD-CE2 4.17Å; K143-Y147 HydrophobicContact CG-CE2 4.33Å; K143-Y147 WeakPolarHBondContact O-CD2 3.25Å; K143-D441 VanDerWaalsContact NZ-CG 3.34Å; K143-D441 IonicContact NZ-OD1 3.31Å; K143-D441 PolarHBondContact NZ-OD1 2.75Å; K143-D441 IonicContact NZ-OD2 2.73Å; K143-D441 PolarHBondContact NZ-OD2 2.94Å; K143-Y579 HydrophobicContact CB-CD1 3.72Å; K143-Y579 HydrophobicContact CB-CE1 3.35Å; K143-Y579 HydrophobicContact CB-CE2 4.47Å; K143-Y579 HydrophobicContact CB-CG 4.44Å; K143-Y579 HydrophobicContact CD-CE1 4.04Å; K143-Y579 HydrophobicContact CD-CE2 4.18Å; K143-Y579 WeakPolarHBondContact CD-OH 3.42Å; K143-Y579 HydrophobicContact CG-CE1 4.27Å
144	G	94.6	Very high	94	Very high	0 Å²	0	14.7 Å²	14.7	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-56.4	-32.9	171.6	0	0	0	0	0	114	F142 G146 Y147 T148	F142-G144 PolarHBondContact O-N 3.37Å; G144-G146 VanDerWaalsContact C-N 3.32Å; G144-G146 PolarHBondContact O-N 3Å; G144-Y147 PolarHBondContact O-N 2.77Å; G144-T148 PolarHBondContact O-N 2.95Å; G144-T148 PolarHBondContact O-OG1 3Å
145	V	95.4	Very high	94.1	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-60	-44	177.5	178.8	0	0	0	0	110.6	W136 F142 K143 Y147 T148 V149 I494 E495 V576	W136-V145 HydrophobicContact CD2-CB 4.45Å; W136-V145 HydrophobicContact CH2-CB 4.49Å; W136-V145 HydrophobicContact CH2-CG1 4.41Å; W136-V145 HydrophobicContact CZ2-CB 3.68Å; W136-V145 HydrophobicContact CZ2-CG1 3.48Å; W136-V145 VanDerWaalsContact CZ2-CG1 3.48Å; W136-V145 HydrophobicContact CZ2-CG2 4.2Å; F142-V145 HydrophobicContact CB-CG2 4.11Å; F142-V145 HydrophobicContact CD1-CG2 4.2Å; F142-V145 VanDerWaalsContact O-CB 3.3Å; F142-V145 WeakPolarHBondContact O-CB 3.24Å; F142-V145 WeakPolarHBondContact O-CG2 3.43Å; F142-V145 PolarHBondContact O-N 3.47Å; K143-V145 PolarHBondContact O-N 2.93Å; V145-Y147 VanDerWaalsContact C-N 3.35Å; V145-Y147 PolarHBondContact O-N 2.87Å; V145-T148 WeakPolarHBondContact O-CB 3.4Å; V145-T148 PolarHBondContact O-N 3.46Å; V145-V149 HydrophobicContact CG1-CG2 4.48Å; V145-V149 VanDerWaalsContact O-CG2 3.31Å; V145-V149 WeakPolarHBondContact O-CG2 3.36Å; V145-V149 PolarHBondContact O-N 3.04Å; V145-I494 HydrophobicContact CG2-CB 4.05Å; V145-I494 HydrophobicContact CG2-CG2 3.48Å; V145-I494 VanDerWaalsContact CG2-CG2 3.48Å; V145-E495 HydrophobicContact CG1-CB 4.04Å; V145-V576 HydrophobicContact CB-CG2 4.49Å; V145-V576 HydrophobicContact CG2-CG1 4.41Å; V145-V576 HydrophobicContact CG2-CG2 3.87Å
146	G	94.9	Very high	94.1	Very high	1 Å²	1	17.8 Å²	17.8	1%	0.01	9%	0.085	C	C	.	.	H	α-helix	trans	-62.7	-38.7	177	0	0	0	0	0	113.6	A132 K143 G144 I150	A132-G146 WeakPolarHBondContact O-CA 3.49Å; K143-G146 PolarHBondContact O-N 3.47Å; G144-G146 VanDerWaalsContact C-N 3.32Å; G144-G146 PolarHBondContact O-N 3Å; G146-I150 WeakPolarHBondContact O-CD1 3.45Å; G146-I150 VanDerWaalsContact O-CG1 3.22Å; G146-I150 WeakPolarHBondContact O-CG1 3.36Å; G146-I150 PolarHBondContact O-N 2.91Å; G146-I150 VanDerWaalsContact O-N 3.07Å
147	Y	95.3	Very high	94	Very high	36 Å²	36	18.2 Å²	18.2	14%	0.141	9%	0.091	C	C	.	.	H	α-helix	trans	-69.7	-38.6	173.5	-66.5	-68.8	0	0	0	112.3	A133 K143 G144 V145 V149 I150 V151 L438 D441 Y579	A133-Y147 HydrophobicContact CB-CD1 4.43Å; A133-Y147 HydrophobicContact CB-CE1 4.23Å; K143-Y147 HydrophobicContact CD-CE2 4.17Å; K143-Y147 HydrophobicContact CG-CE2 4.33Å; K143-Y147 WeakPolarHBondContact O-CD2 3.25Å; G144-Y147 PolarHBondContact O-N 2.77Å; V145-Y147 VanDerWaalsContact C-N 3.35Å; V145-Y147 PolarHBondContact O-N 2.87Å; Y147-V149 VanDerWaalsContact C-N 3.31Å; Y147-V149 PolarHBondContact O-N 3.34Å; Y147-I150 PolarHBondContact O-N 3.21Å; Y147-V151 VanDerWaalsContact O-CG2 3.3Å; Y147-V151 WeakPolarHBondContact O-CG2 3.24Å; Y147-V151 PolarHBondContact O-N 2.64Å; Y147-L438 HydrophobicContact CE1-CD2 4.42Å; Y147-D441 PolarHBondContact OH-OD2 2.71Å; Y147-Y579 HydrophobicContact CD2-CD2 4.25Å; Y147-Y579 HydrophobicContact CE2-CD2 4.02Å; Y147-Y579 AromaticContact CE2-CE2 3.84Å; Y147-Y579 HydrophobicContact CE2-CE2 3.84Å
148	T	95.4	Very high	94.1	Very high	0 Å²	0	15.8 Å²	15.8	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-53.9	-50.6	172.9	-66.8	0	0	0	0	110.6	G144 V145 I150 V151 I152 S572 F575	G144-T148 PolarHBondContact O-N 2.95Å; G144-T148 PolarHBondContact O-OG1 3Å; V145-T148 WeakPolarHBondContact O-CB 3.4Å; V145-T148 PolarHBondContact O-N 3.46Å; T148-I150 PolarHBondContact O-N 3.43Å; T148-V151 PolarHBondContact O-N 3.44Å; T148-I152 HydrophobicContact CG2-CD1 3.79Å; T148-I152 VanDerWaalsContact O-CG1 3.28Å; T148-I152 WeakPolarHBondContact O-CG1 3.5Å; T148-I152 PolarHBondContact O-N 3.19Å; T148-S572 WeakPolarHBondContact CB-O 3.25Å; T148-S572 VanDerWaalsContact CG2-O 3.3Å; T148-S572 WeakPolarHBondContact CG2-O 3.35Å; T148-S572 PolarHBondContact OG1-O 2.83Å; T148-F575 WeakPolarHBondContact OG1-CB 3.34Å
149	V	94.3	Very high	94.2	Very high	3 Å²	3	16 Å²	16	2%	0.018	8%	0.081	C	C	.	.	H	α-helix	trans	-63.9	-40.9	-179.3	170.4	0	0	0	0	112.3	V145 Y147 I152 A153 G329 F330	V145-V149 HydrophobicContact CG1-CG2 4.48Å; V145-V149 VanDerWaalsContact O-CG2 3.31Å; V145-V149 WeakPolarHBondContact O-CG2 3.36Å; V145-V149 PolarHBondContact O-N 3.04Å; Y147-V149 VanDerWaalsContact C-N 3.31Å; Y147-V149 PolarHBondContact O-N 3.34Å; V149-I152 PolarHBondContact O-N 3.47Å; V149-A153 PolarHBondContact O-N 3.12Å; V149-G329 VanDerWaalsContact CG1-O 3.28Å; V149-G329 WeakPolarHBondContact CG1-O 3.11Å; V149-G329 WeakPolarHBondContact CG2-O 3.36Å; V149-F330 WeakPolarHBondContact CG1-O 3.07Å
150	I	94.9	Very high	94.3	Very high	9 Å²	9	16.9 Å²	16.9	5%	0.046	8%	0.084	C	C	.	.	H	α-helix	trans	-62	-43.5	174.6	-71.4	165.5	0	0	0	111.4	A133 G146 Y147 T148 A153 L154 V434 L438	A133-I150 HydrophobicContact CB-CD1 3.76Å; G146-I150 WeakPolarHBondContact O-CD1 3.45Å; G146-I150 VanDerWaalsContact O-CG1 3.22Å; G146-I150 WeakPolarHBondContact O-CG1 3.36Å; G146-I150 PolarHBondContact O-N 2.91Å; G146-I150 VanDerWaalsContact O-N 3.07Å; Y147-I150 PolarHBondContact O-N 3.21Å; T148-I150 PolarHBondContact O-N 3.43Å; I150-A153 PolarHBondContact O-N 3Å; I150-L154 WeakPolarHBondContact O-CB 3.37Å; I150-L154 PolarHBondContact O-N 2.93Å; I150-V434 HydrophobicContact CG2-CB 4.41Å; I150-V434 HydrophobicContact CG2-CG1 4.1Å; I150-V434 HydrophobicContact CG2-CG2 4.27Å; I150-L438 HydrophobicContact CD1-CD2 4.37Å; I150-L438 HydrophobicContact CD1-CG 4.42Å; I150-L438 HydrophobicContact CG2-CD1 4.24Å; I150-L438 HydrophobicContact CG2-CG 4.23Å
151	V	95.3	Very high	94.4	Very high	21 Å²	21	16.8 Å²	16.8	13%	0.127	8%	0.083	C	C	.	.	H	α-helix	trans	-66.8	-40.8	179.5	170.6	0	0	0	0	111	Y147 T148 L154 Y155 F575	Y147-V151 VanDerWaalsContact O-CG2 3.3Å; Y147-V151 WeakPolarHBondContact O-CG2 3.24Å; Y147-V151 PolarHBondContact O-N 2.64Å; T148-V151 PolarHBondContact O-N 3.44Å; V151-L154 WeakPolarHBondContact O-CB 3.3Å; V151-L154 PolarHBondContact O-N 3.48Å; V151-Y155 HydrophobicContact CG1-CD1 4.42Å; V151-Y155 HydrophobicContact CG1-CD2 4.07Å; V151-Y155 HydrophobicContact CG1-CE1 3.92Å; V151-Y155 HydrophobicContact CG1-CE2 3.51Å; V151-Y155 HydrophobicContact CG1-CG 4.5Å; V151-Y155 VanDerWaalsContact CG1-CZ 3.43Å; V151-Y155 PolarHBondContact O-N 2.92Å; V151-F575 HydrophobicContact CG2-CD2 4.37Å; V151-F575 HydrophobicContact CG2-CE2 3.86Å; V151-F575 HydrophobicContact CG2-CZ 4.19Å
152	I	94.2	Very high	94.5	Very high	0 Å²	0	15 Å²	15	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-59.8	-49.3	174.3	-70	166.3	0	0	0	110.7	T148 V149 L154 Y155 V156 F330 A484 A487 I488	T148-I152 HydrophobicContact CG2-CD1 3.79Å; T148-I152 VanDerWaalsContact O-CG1 3.28Å; T148-I152 WeakPolarHBondContact O-CG1 3.5Å; T148-I152 PolarHBondContact O-N 3.19Å; V149-I152 PolarHBondContact O-N 3.47Å; I152-L154 PolarHBondContact O-N 3.07Å; I152-Y155 PolarHBondContact O-N 3.08Å; I152-Y155 VanDerWaalsContact O-N 3.12Å; I152-V156 PolarHBondContact O-N 3.4Å; I152-F330 HydrophobicContact CG2-CD1 4.12Å; I152-F330 HydrophobicContact CG2-CE1 3.9Å; I152-A484 HydrophobicContact CG2-CB 4.4Å; I152-A487 HydrophobicContact CD1-CB 3.91Å; I152-A487 HydrophobicContact CG1-CB 4.18Å; I152-I488 HydrophobicContact CD1-CG1 4.14Å; I152-I488 HydrophobicContact CG2-CD1 3.95Å; I152-I488 HydrophobicContact CG2-CG1 3.53Å
153	A	93.9	Very high	94.5	Very high	6 Å²	6	14.1 Å²	14.1	5%	0.05	7%	0.071	C	C	.	.	H	α-helix	trans	-59.5	-36.8	178.1	0	0	0	0	0	111.9	V149 I150 G157 V434	V149-A153 PolarHBondContact O-N 3.12Å; I150-A153 PolarHBondContact O-N 3Å; A153-G157 PolarHBondContact O-N 2.83Å; A153-G157 VanDerWaalsContact O-N 3.08Å; A153-V434 HydrophobicContact CB-CG2 3.86Å
154	L	94.4	Very high	94.6	Very high	53 Å²	53	12.7 Å²	12.7	28%	0.277	7%	0.065	S	C	.	.	H	α-helix	trans	-65.3	-44.4	174.2	-176.7	65.8	0	0	0	112.2	I150 V151 I152 G157 F158 V434 T460	I150-L154 WeakPolarHBondContact O-CB 3.37Å; I150-L154 PolarHBondContact O-N 2.93Å; V151-L154 WeakPolarHBondContact O-CB 3.3Å; V151-L154 PolarHBondContact O-N 3.48Å; I152-L154 PolarHBondContact O-N 3.07Å; L154-G157 PolarHBondContact O-N 2.92Å; L154-F158 HydrophobicContact CD1-CE1 3.86Å; L154-F158 HydrophobicContact CD1-CZ 4.18Å; L154-F158 HydrophobicContact CD2-CZ 4.07Å; L154-F158 HydrophobicContact CG-CE1 3.85Å; L154-F158 HydrophobicContact CG-CE2 4.49Å; L154-F158 HydrophobicContact CG-CZ 3.69Å; L154-F158 WeakPolarHBondContact O-CD1 3.28Å; L154-F158 PolarHBondContact O-N 3.41Å; L154-V434 HydrophobicContact CB-CG2 4.32Å; L154-T460 HydrophobicContact CD1-CG2 3.64Å
155	Y	94.5	Very high	94.7	Very high	45 Å²	45	12.7 Å²	12.7	18%	0.176	7%	0.065	C	C	.	.	H	α-helix	trans	-64.3	-40.4	177.8	-65.6	-20.7	0	0	0	112.8	V151 I152 G157 F158 Y159 A483 V568 S571	V151-Y155 HydrophobicContact CG1-CD1 4.42Å; V151-Y155 HydrophobicContact CG1-CD2 4.07Å; V151-Y155 HydrophobicContact CG1-CE1 3.92Å; V151-Y155 HydrophobicContact CG1-CE2 3.51Å; V151-Y155 HydrophobicContact CG1-CG 4.5Å; V151-Y155 VanDerWaalsContact CG1-CZ 3.43Å; V151-Y155 PolarHBondContact O-N 2.92Å; I152-Y155 PolarHBondContact O-N 3.08Å; I152-Y155 VanDerWaalsContact O-N 3.12Å; Y155-G157 VanDerWaalsContact C-N 3.27Å; Y155-G157 PolarHBondContact O-N 3.37Å; Y155-F158 HydrophobicContact CD1-CD2 4Å; Y155-F158 AromaticContact CD1-CE2 3.59Å; Y155-F158 HydrophobicContact CD1-CE2 3.59Å; Y155-F158 HydrophobicContact CD1-CZ 4.48Å; Y155-F158 HydrophobicContact CE1-CE2 4.12Å; Y155-F158 WeakPolarHBondContact O-CB 3.46Å; Y155-F158 PolarHBondContact O-N 3.11Å; Y155-F158 VanDerWaalsContact O-N 3.09Å; Y155-Y159 WeakPolarHBondContact O-CD1 3.21Å; Y155-A483 HydrophobicContact CD2-CB 4.23Å; Y155-A483 HydrophobicContact CG-CB 4.39Å; Y155-V568 HydrophobicContact CD2-CG1 3.82Å; Y155-V568 HydrophobicContact CE2-CG1 3.74Å; Y155-V568 HydrophobicContact CG-CG1 4.48Å; Y155-S571 WeakPolarHBondContact CE2-OG 3.37Å; Y155-S571 PolarHBondContact OH-OG 3.17Å
156	V	93.5	Very high	94.7	Very high	22 Å²	22	12.7 Å²	12.7	13%	0.133	7%	0.065	C	C	.	.	H	α-helix	trans	-61.6	-39.8	173.3	175	0	0	0	0	110.9	I152 F158 Y159 Y160 F330 A484	I152-V156 PolarHBondContact O-N 3.4Å; V156-F158 PolarHBondContact O-N 3.46Å; V156-F158 VanDerWaalsContact O-N 3.14Å; V156-Y159 HydrophobicContact CB-CE1 4.25Å; V156-Y159 HydrophobicContact CG1-CE1 4.44Å; V156-Y159 HydrophobicContact CG2-CE1 4.1Å; V156-Y159 PolarHBondContact O-N 3.44Å; V156-Y160 HydrophobicContact CG1-CG 4.47Å; V156-Y160 WeakPolarHBondContact O-CB 3.38Å; V156-Y160 PolarHBondContact O-N 3.12Å; V156-F330 HydrophobicContact CB-CE1 4.39Å; V156-F330 HydrophobicContact CG2-CE1 3.76Å; V156-F330 HydrophobicContact CG2-CZ 4.38Å; V156-A484 HydrophobicContact CG2-CB 3.72Å
157	G	93.2	Very high	94.8	Very high	12 Å²	12	12.7 Å²	12.7	12%	0.124	6%	0.064	C	C	.	.	H	α-helix	trans	-58	-25.2	173.5	0	0	0	0	0	114.7	A153 L154 Y155 N161	A153-G157 PolarHBondContact O-N 2.83Å; A153-G157 VanDerWaalsContact O-N 3.08Å; L154-G157 PolarHBondContact O-N 2.92Å; Y155-G157 VanDerWaalsContact C-N 3.27Å; Y155-G157 PolarHBondContact O-N 3.37Å; G157-N161 PolarHBondContact O-ND2 3.21Å
158	F	94.1	Very high	94.8	Very high	24 Å²	24	11.4 Å²	11.4	11%	0.105	6%	0.06	C	C	.	.	H	α-helix	trans	-71.1	-37.7	179.9	-62.1	-24.4	0	0	0	113.4	L154 Y155 V156 T460 V463 A464 L479	L154-F158 HydrophobicContact CD1-CE1 3.86Å; L154-F158 HydrophobicContact CD1-CZ 4.18Å; L154-F158 HydrophobicContact CD2-CZ 4.07Å; L154-F158 HydrophobicContact CG-CE1 3.85Å; L154-F158 HydrophobicContact CG-CE2 4.49Å; L154-F158 HydrophobicContact CG-CZ 3.69Å; L154-F158 WeakPolarHBondContact O-CD1 3.28Å; L154-F158 PolarHBondContact O-N 3.41Å; Y155-F158 HydrophobicContact CD1-CD2 4Å; Y155-F158 AromaticContact CD1-CE2 3.59Å; Y155-F158 HydrophobicContact CD1-CE2 3.59Å; Y155-F158 HydrophobicContact CD1-CZ 4.48Å; Y155-F158 HydrophobicContact CE1-CE2 4.12Å; Y155-F158 WeakPolarHBondContact O-CB 3.46Å; Y155-F158 PolarHBondContact O-N 3.11Å; Y155-F158 VanDerWaalsContact O-N 3.09Å; V156-F158 PolarHBondContact O-N 3.46Å; V156-F158 VanDerWaalsContact O-N 3.14Å; F158-T460 HydrophobicContact CD1-CG2 4.01Å; F158-T460 HydrophobicContact CE1-CG2 3.92Å; F158-V463 HydrophobicContact CB-CB 4.5Å; F158-V463 HydrophobicContact CB-CG1 4.02Å; F158-V463 HydrophobicContact CD1-CB 3.74Å; F158-V463 HydrophobicContact CD1-CG1 3.95Å; F158-V463 HydrophobicContact CD1-CG2 4.32Å; F158-V463 HydrophobicContact CD2-CB 4.24Å; F158-V463 HydrophobicContact CD2-CG1 3.55Å; F158-V463 HydrophobicContact CE1-CB 3.89Å; F158-V463 HydrophobicContact CE1-CG1 4.25Å; F158-V463 HydrophobicContact CE1-CG2 3.95Å; F158-V463 HydrophobicContact CE2-CB 4.36Å; F158-V463 HydrophobicContact CE2-CG1 3.87Å; F158-V463 HydrophobicContact CE2-CG2 4.39Å; F158-V463 HydrophobicContact CG-CB 3.93Å; F158-V463 HydrophobicContact CG-CG1 3.59Å; F158-V463 HydrophobicContact CZ-CB 4.2Å; F158-V463 HydrophobicContact CZ-CG1 4.21Å; F158-V463 HydrophobicContact CZ-CG2 3.98Å; F158-A464 WeakPolarHBondContact O-CA 3.48Å; F158-A464 VanDerWaalsContact O-CB 3.22Å; F158-A464 WeakPolarHBondContact O-CB 3.39Å; F158-L479 HydrophobicContact CB-CD1 4.46Å
159	Y	93.5	Very high	94.9	Very high	8 Å²	8	12.1 Å²	12.1	3%	0.031	6%	0.063	C	C	.	.	H	α-helix	trans	-106.2	-29.2	-177.7	73.2	-96.5	0	0	0	112.8	Y155 V156 N161 V162 I163 L476 L479 D480	Y155-Y159 WeakPolarHBondContact O-CD1 3.21Å; V156-Y159 HydrophobicContact CB-CE1 4.25Å; V156-Y159 HydrophobicContact CG1-CE1 4.44Å; V156-Y159 HydrophobicContact CG2-CE1 4.1Å; V156-Y159 PolarHBondContact O-N 3.44Å; Y159-N161 VanDerWaalsContact C-N 3.33Å; Y159-N161 PolarHBondContact O-N 3.03Å; Y159-V162 VanDerWaalsContact O-CB 3.26Å; Y159-V162 WeakPolarHBondContact O-CB 3.21Å; Y159-V162 PolarHBondContact O-N 3Å; Y159-V162 VanDerWaalsContact O-N 3.11Å; Y159-I163 HydrophobicContact CD2-CD1 4.47Å; Y159-L476 HydrophobicContact CD2-CG 4.29Å; Y159-L479 HydrophobicContact CD1-CB 3.62Å; Y159-L479 HydrophobicContact CD1-CD1 4.49Å; Y159-L479 HydrophobicContact CE1-CB 4.25Å; Y159-L479 HydrophobicContact CG-CB 4.19Å; Y159-D480 HydrophobicContact CD2-CB 4.35Å; Y159-D480 HydrophobicContact CE2-CB 3.97Å; Y159-D480 PolarHBondContact OH-OD1 3.48Å
160	Y	93.8	Very high	95	Very high	19 Å²	19	12 Å²	12	8%	0.075	6%	0.062	C	C	.	.	H	α-helix	trans	-64.9	-38.4	-177.9	-167.5	-100.4	0	0	0	112.1	L84 V156 V162 I163 I164 G423 S426	L84-Y160 VanDerWaalsContact CD1-OH 3.28Å; L84-Y160 WeakPolarHBondContact CD1-OH 3.37Å; V156-Y160 HydrophobicContact CG1-CG 4.47Å; V156-Y160 WeakPolarHBondContact O-CB 3.38Å; V156-Y160 PolarHBondContact O-N 3.12Å; Y160-V162 PolarHBondContact O-N 2.87Å; Y160-I163 HydrophobicContact CD2-CD1 4.35Å; Y160-I163 WeakPolarHBondContact O-CB 3.25Å; Y160-I163 PolarHBondContact O-N 3.29Å; Y160-I163 VanDerWaalsContact O-N 3.09Å; Y160-I164 HydrophobicContact CD1-CD1 4.18Å; Y160-I164 HydrophobicContact CE1-CD1 4.23Å; Y160-I164 PolarHBondContact O-N 3.3Å; Y160-G423 WeakPolarHBondContact CE1-O 3.37Å; Y160-S426 PolarHBondContact OH-OG 3.11Å
161	N	95.2	Very high	95.1	Very high	1 Å²	1	12.4 Å²	12.4	1%	0.005	7%	0.065	C	C	.	.	H	α-helix	trans	-61.1	-25.1	175.4	-76.3	-37.5	0	0	0	113.9	G157 Y159 I164 A165 L248 L255 S427	G157-N161 PolarHBondContact O-ND2 3.21Å; Y159-N161 VanDerWaalsContact C-N 3.33Å; Y159-N161 PolarHBondContact O-N 3.03Å; N161-I164 PolarHBondContact O-N 3.18Å; N161-A165 PolarHBondContact O-N 3.41Å; N161-L248 HydrophobicContact CB-CD1 4.03Å; N161-L255 WeakPolarHBondContact OD1-CD1 3.41Å; N161-S427 PolarHBondContact OD1-OG 2.86Å
162	V	95.7	Very high	95.1	Very high	0 Å²	0	16.5 Å²	16.5	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-70.8	-37.4	177.4	177.6	0	0	0	0	111	Y159 Y160 I164 A165 W166 A464 C467 I468 L476	Y159-V162 VanDerWaalsContact O-CB 3.26Å; Y159-V162 WeakPolarHBondContact O-CB 3.21Å; Y159-V162 PolarHBondContact O-N 3Å; Y159-V162 VanDerWaalsContact O-N 3.11Å; Y160-V162 PolarHBondContact O-N 2.87Å; V162-I164 VanDerWaalsContact C-N 3.3Å; V162-I164 PolarHBondContact O-N 2.85Å; V162-A165 CarbonylContact O-C 3.51Å; V162-A165 WeakPolarHBondContact O-CB 3.17Å; V162-A165 PolarHBondContact O-N 3.49Å; V162-A165 VanDerWaalsContact O-N 3.14Å; V162-W166 HydrophobicContact CG1-CD2 4.22Å; V162-W166 HydrophobicContact CG1-CH2 4.37Å; V162-W166 HydrophobicContact CG1-CZ2 3.61Å; V162-W166 PolarHBondContact O-N 2.88Å; V162-A464 HydrophobicContact CG2-CB 4.07Å; V162-C467 HydrophobicContact CB-CB 4.5Å; V162-C467 HydrophobicContact CG1-CB 4.49Å; V162-C467 HydrophobicContact CG2-CB 3.65Å; V162-I468 HydrophobicContact CB-CG2 4.34Å; V162-I468 HydrophobicContact CG1-CG2 3.59Å; V162-I468 HydrophobicContact CG2-CG2 4.02Å; V162-L476 HydrophobicContact CB-CD1 4.17Å; V162-L476 HydrophobicContact CG1-CD1 4.17Å
163	I	94.5	Very high	95.2	Very high	6 Å²	6	17.8 Å²	17.8	3%	0.031	9%	0.09	C	C	.	.	H	α-helix	trans	-65.6	-37.6	176	-62.4	155.9	0	0	0	110.7	L84 W88 Y159 Y160 A165 W166 S167 F395 L476	L84-I163 HydrophobicContact CD2-CG2 3.49Å; L84-I163 VanDerWaalsContact CD2-CG2 3.49Å; W88-I163 HydrophobicContact CH2-CD1 3.64Å; W88-I163 HydrophobicContact CH2-CG1 4.11Å; W88-I163 HydrophobicContact CH2-CG2 3.7Å; W88-I163 HydrophobicContact CZ2-CD1 4.2Å; W88-I163 HydrophobicContact CZ3-CG2 3.98Å; Y159-I163 HydrophobicContact CD2-CD1 4.47Å; Y160-I163 HydrophobicContact CD2-CD1 4.35Å; Y160-I163 WeakPolarHBondContact O-CB 3.25Å; Y160-I163 PolarHBondContact O-N 3.29Å; Y160-I163 VanDerWaalsContact O-N 3.09Å; I163-A165 VanDerWaalsContact C-N 3.34Å; I163-W166 HydrophobicContact CG1-CE3 4.2Å; I163-W166 HydrophobicContact CG1-CZ3 4.12Å; I163-W166 PolarHBondContact O-N 3.15Å; I163-S167 PolarHBondContact O-N 3.3Å; I163-S167 PolarHBondContact O-OG 3.16Å; I163-F395 HydrophobicContact CG2-CE2 4.1Å; I163-F395 HydrophobicContact CG2-CZ 4.21Å; I163-L476 HydrophobicContact CG1-CD1 4.18Å
164	I	95.9	Very high	95.3	Very high	1 Å²	1	17.5 Å²	17.5	1%	0.005	9%	0.087	C	C	.	.	H	α-helix	trans	-65.1	-41.3	173.2	-48.7	176.1	0	0	0	110	Y160 N161 V162 W166 S167 L168 V251 G423 I424	Y160-I164 HydrophobicContact CD1-CD1 4.18Å; Y160-I164 HydrophobicContact CE1-CD1 4.23Å; Y160-I164 PolarHBondContact O-N 3.3Å; N161-I164 PolarHBondContact O-N 3.18Å; V162-I164 VanDerWaalsContact C-N 3.3Å; V162-I164 PolarHBondContact O-N 2.85Å; I164-W166 PolarHBondContact O-N 3.4Å; I164-S167 WeakPolarHBondContact O-CB 3.35Å; I164-S167 PolarHBondContact O-N 2.93Å; I164-L168 PolarHBondContact O-N 2.92Å; I164-V251 HydrophobicContact CB-CG1 4.01Å; I164-V251 HydrophobicContact CB-CG2 4.14Å; I164-V251 HydrophobicContact CD1-CG1 4.32Å; I164-V251 HydrophobicContact CG2-CB 4.47Å; I164-V251 HydrophobicContact CG2-CG1 3.87Å; I164-V251 HydrophobicContact CG2-CG2 3.68Å; I164-G423 VanDerWaalsContact CD1-C 3.41Å; I164-G423 VanDerWaalsContact CD1-O 3.26Å; I164-G423 WeakPolarHBondContact CD1-O 3.05Å; I164-I424 HydrophobicContact CG2-CG1 4.07Å
165	A	96.8	Very high	95.2	Very high	0 Å²	0	20.8 Å²	20.8	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-63.9	-39.1	176.6	0	0	0	0	0	112.2	N161 V162 I163 L168 H169 C247 L248 V251	N161-A165 PolarHBondContact O-N 3.41Å; V162-A165 CarbonylContact O-C 3.51Å; V162-A165 WeakPolarHBondContact O-CB 3.17Å; V162-A165 PolarHBondContact O-N 3.49Å; V162-A165 VanDerWaalsContact O-N 3.14Å; I163-A165 VanDerWaalsContact C-N 3.34Å; A165-L168 PolarHBondContact O-N 3.11Å; A165-H169 PolarHBondContact O-N 3.29Å; A165-C247 HydrophobicContact CB-CB 4.14Å; A165-C247 WeakPolarHBondContact O-CB 3.23Å; A165-L248 HydrophobicContact CB-CB 4.03Å; A165-L248 HydrophobicContact CB-CD1 4.15Å; A165-V251 HydrophobicContact CB-CG2 4.4Å
166	W	96.1	Very high	95.1	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-62.2	-44.7	171.1	-63	-21	0	0	0	111.5	V162 I163 I164 L168 H169 Y170 Y221 L226 A391 F395 I473 L476	V162-W166 HydrophobicContact CG1-CD2 4.22Å; V162-W166 HydrophobicContact CG1-CH2 4.37Å; V162-W166 HydrophobicContact CG1-CZ2 3.61Å; V162-W166 PolarHBondContact O-N 2.88Å; I163-W166 HydrophobicContact CG1-CE3 4.2Å; I163-W166 HydrophobicContact CG1-CZ3 4.12Å; I163-W166 PolarHBondContact O-N 3.15Å; I164-W166 PolarHBondContact O-N 3.4Å; W166-L168 VanDerWaalsContact C-N 3.29Å; W166-L168 PolarHBondContact O-N 2.95Å; W166-H169 WeakPolarHBondContact O-CB 3.33Å; W166-H169 PolarHBondContact O-N 3.44Å; W166-H169 VanDerWaalsContact O-N 3.16Å; W166-Y170 WeakPolarHBondContact O-CD2 3.26Å; W166-Y170 PolarHBondContact O-N 3.36Å; W166-Y221 HydrophobicContact CE3-CE2 4.49Å; W166-Y221 WeakPolarHBondContact CZ3-OH 3.41Å; W166-L226 HydrophobicContact CZ2-CD2 3.67Å; W166-A391 HydrophobicContact CZ3-CB 4.06Å; W166-F395 HydrophobicContact CB-CE1 3.84Å; W166-F395 HydrophobicContact CB-CE2 4.27Å; W166-F395 HydrophobicContact CB-CZ 3.7Å; W166-F395 HydrophobicContact CE3-CD2 4.21Å; W166-F395 AromaticContact CE3-CE2 3.81Å; W166-F395 HydrophobicContact CE3-CE2 3.81Å; W166-F395 HydrophobicContact CE3-CZ 4.36Å; W166-I473 HydrophobicContact CH2-CD1 3.6Å; W166-I473 HydrophobicContact CZ2-CD1 4.45Å; W166-I473 HydrophobicContact CZ3-CD1 4.33Å; W166-L476 HydrophobicContact CH2-CD1 3.61Å; W166-L476 HydrophobicContact CH2-CD2 4.41Å; W166-L476 HydrophobicContact CZ2-CD1 4.21Å; W166-L476 HydrophobicContact CZ3-CD1 4.13Å
167	S	95.8	Very high	94.9	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-59.3	-41.1	176.6	-55.2	0	0	0	0	111.8	I163 I164 Y170 L171	I163-S167 PolarHBondContact O-N 3.3Å; I163-S167 PolarHBondContact O-OG 3.16Å; I164-S167 WeakPolarHBondContact O-CB 3.35Å; I164-S167 PolarHBondContact O-N 2.93Å; S167-Y170 PolarHBondContact O-N 3.15Å; S167-L171 WeakPolarHBondContact O-CB 3.2Å; S167-L171 PolarHBondContact O-N 2.98Å
168	L	97	Very high	94.7	Very high	9 Å²	9	36.8 Å²	36.8	5%	0.047	17%	0.169	C	C	.	.	H	α-helix	trans	-66.8	-41.3	175.5	-178	60	0	0	0	112.3	I164 A165 W166 L171 F172 C247 V250 V251 L420	I164-L168 PolarHBondContact O-N 2.92Å; A165-L168 PolarHBondContact O-N 3.11Å; W166-L168 VanDerWaalsContact C-N 3.29Å; W166-L168 PolarHBondContact O-N 2.95Å; L168-L171 HydrophobicContact CD1-CD2 4.37Å; L168-L171 WeakPolarHBondContact O-CB 3.48Å; L168-L171 PolarHBondContact O-N 3.16Å; L168-F172 HydrophobicContact CD1-CD2 4.07Å; L168-F172 HydrophobicContact CD1-CE2 3.46Å; L168-F172 VanDerWaalsContact CD1-CE2 3.46Å; L168-F172 HydrophobicContact CD1-CZ 3.79Å; L168-F172 HydrophobicContact CD2-CE2 4.08Å; L168-F172 HydrophobicContact CG-CD2 4.02Å; L168-F172 HydrophobicContact CG-CE2 3.55Å; L168-F172 HydrophobicContact CG-CZ 4.36Å; L168-F172 VanDerWaalsContact O-CD2 3.25Å; L168-F172 WeakPolarHBondContact O-CD2 3.32Å; L168-F172 PolarHBondContact O-N 2.99Å; L168-F172 VanDerWaalsContact O-N 3.08Å; L168-C247 HydrophobicContact CB-CB 4.44Å; L168-C247 HydrophobicContact CD2-CB 4.15Å; L168-C247 HydrophobicContact CG-CB 4.41Å; L168-V250 HydrophobicContact CD2-CB 3.73Å; L168-V250 HydrophobicContact CD2-CG1 3.61Å; L168-V251 HydrophobicContact CD2-CG2 4.13Å; L168-L420 HydrophobicContact CB-CD1 3.95Å; L168-L420 HydrophobicContact CD1-CD1 3.72Å; L168-L420 HydrophobicContact CG-CD1 4.36Å
169	H	96.9	Very high	94.6	Very high	15 Å²	15	35.9 Å²	35.9	7%	0.069	17%	0.165	C	C	.	.	H	α-helix	trans	-59.8	-49	175	178.4	81.1	0	0	0	110.9	A165 W166 L171 F172 S173 E243 L244	A165-H169 PolarHBondContact O-N 3.29Å; W166-H169 WeakPolarHBondContact O-CB 3.33Å; W166-H169 PolarHBondContact O-N 3.44Å; W166-H169 VanDerWaalsContact O-N 3.16Å; H169-L171 VanDerWaalsContact C-N 3.3Å; H169-L171 PolarHBondContact O-N 2.63Å; H169-F172 PolarHBondContact O-N 2.78Å; H169-S173 WeakPolarHBondContact O-CB 3.35Å; H169-S173 PolarHBondContact O-N 3.13Å; H169-S173 PolarHBondContact O-OG 3.31Å; H169-S173 VanDerWaalsContact O-OG 3.12Å; H169-E243 IonicContact CE1-OE2 2.8Å; H169-E243 PolarHBondContact CE1-OE2 2.96Å; H169-E243 VanDerWaalsContact CE1-OE2 3.29Å; H169-L244 HydrophobicContact CB-CD2 3.94Å
170	Y	96.4	Very high	94.5	Very high	1 Å²	1	36.7 Å²	36.7	0%	0.004	17%	0.171	C	C	.	.	H	α-helix	trans	-62.6	-34.6	176.5	-90.8	-94.6	0	0	0	113.1	W166 S167 S173 S174 W181 Y220 Y221 V225 F395 P399 F416	W166-Y170 WeakPolarHBondContact O-CD2 3.26Å; W166-Y170 PolarHBondContact O-N 3.36Å; S167-Y170 PolarHBondContact O-N 3.15Å; Y170-S173 PolarHBondContact O-N 3.33Å; Y170-S174 WeakPolarHBondContact O-CB 3.37Å; Y170-S174 PolarHBondContact O-N 2.89Å; Y170-S174 PolarHBondContact O-OG 3.31Å; Y170-W181 AromaticContact CD1-CE3 3.99Å; Y170-W181 HydrophobicContact CD1-CE3 3.99Å; Y170-W181 AromaticContact CD1-CH2 3.8Å; Y170-W181 HydrophobicContact CD1-CH2 3.8Å; Y170-W181 AromaticContact CD1-CZ3 3.47Å; Y170-W181 HydrophobicContact CD1-CZ3 3.47Å; Y170-W181 VanDerWaalsContact CD1-CZ3 3.47Å; Y170-W181 HydrophobicContact CE1-CD2 4.46Å; Y170-W181 AromaticContact CE1-CE3 3.82Å; Y170-W181 HydrophobicContact CE1-CE3 3.82Å; Y170-W181 HydrophobicContact CE1-CH2 4.42Å; Y170-W181 AromaticContact CE1-CZ3 3.81Å; Y170-W181 HydrophobicContact CE1-CZ3 3.81Å; Y170-Y220 HydrophobicContact CD1-CE1 4.24Å; Y170-Y220 AromaticContact CE1-CD1 3.81Å; Y170-Y220 HydrophobicContact CE1-CD1 3.81Å; Y170-Y220 AromaticContact CE1-CE1 3.64Å; Y170-Y220 HydrophobicContact CE1-CE1 3.64Å; Y170-Y220 HydrophobicContact CE2-CE1 4.43Å; Y170-Y220 AromaticContact CZ-CD1 3.81Å; Y170-Y220 AromaticContact CZ-CE1 3.74Å; Y170-Y220 WeakPolarHBondContact OH-CD1 3.25Å; Y170-Y221 HydrophobicContact CE2-CD2 4.22Å; Y170-Y221 WeakPolarHBondContact OH-CB 3.43Å; Y170-V225 HydrophobicContact CE2-CG1 4.44Å; Y170-V225 HydrophobicContact CE2-CG2 3.96Å; Y170-F395 AromaticContact CD2-CD1 3.56Å; Y170-F395 HydrophobicContact CD2-CD1 3.56Å; Y170-F395 AromaticContact CD2-CE1 3.99Å; Y170-F395 HydrophobicContact CD2-CE1 3.99Å; Y170-F395 HydrophobicContact CE2-CB 4.17Å; Y170-F395 AromaticContact CE2-CD1 3.57Å; Y170-F395 HydrophobicContact CE2-CD1 3.57Å; Y170-F395 HydrophobicContact CE2-CE1 4.38Å; Y170-F395 HydrophobicContact CE2-CG 4.21Å; Y170-F395 HydrophobicContact CG-CD1 4.13Å; Y170-F395 PolarHBondContact OH-O 3.38Å; Y170-F395 VanDerWaalsContact OH-O 3.09Å; Y170-P399 HydrophobicContact CE1-CG 4.27Å; Y170-F416 VanDerWaalsContact CB-CZ 3.44Å; Y170-F416 AromaticContact CD1-CE1 3.79Å; Y170-F416 HydrophobicContact CD1-CE1 3.79Å; Y170-F416 AromaticContact CD1-CE2 3.76Å; Y170-F416 HydrophobicContact CD1-CE2 3.76Å; Y170-F416 AromaticContact CD1-CZ 3.2Å; Y170-F416 HydrophobicContact CD1-CZ 3.2Å; Y170-F416 HydrophobicContact CD2-CE1 4.48Å; Y170-F416 HydrophobicContact CE1-CZ 4.1Å; Y170-F416 HydrophobicContact CG-CD1 4.3Å; Y170-F416 AromaticContact CG-CE1 3.63Å; Y170-F416 HydrophobicContact CG-CE1 3.63Å; Y170-F416 HydrophobicContact CG-CE2 4.16Å; Y170-F416 AromaticContact CG-CZ 3.54Å; Y170-F416 HydrophobicContact CG-CZ 3.54Å
171	L	96.3	Very high	94.4	Very high	18 Å²	18	36 Å²	36	9%	0.094	17%	0.168	C	C	.	.	H	α-helix	trans	-61.1	-46.6	173.6	177.5	59.9	0	0	0	111.5	S167 L168 H169 S174 M175 I413 F416 I417	S167-L171 WeakPolarHBondContact O-CB 3.2Å; S167-L171 PolarHBondContact O-N 2.98Å; L168-L171 HydrophobicContact CD1-CD2 4.37Å; L168-L171 WeakPolarHBondContact O-CB 3.48Å; L168-L171 PolarHBondContact O-N 3.16Å; H169-L171 VanDerWaalsContact C-N 3.3Å; H169-L171 PolarHBondContact O-N 2.63Å; L171-S174 WeakPolarHBondContact O-CB 3.17Å; L171-S174 PolarHBondContact O-N 3.42Å; L171-M175 HydrophobicContact CG-CE 4.35Å; L171-I413 HydrophobicContact CD1-CB 4.41Å; L171-I413 HydrophobicContact CD1-CG2 4.02Å; L171-F416 HydrophobicContact CB-CB 3.96Å; L171-F416 HydrophobicContact CD1-CB 4.35Å; L171-I417 HydrophobicContact CD1-CD1 4.39Å; L171-I417 HydrophobicContact CD1-CG1 3.84Å; L171-I417 HydrophobicContact CD2-CG1 4.07Å
172	F	96.4	Very high	94	Very high	107 Å²	107	38.8 Å²	38.8	47%	0.469	18%	0.183	S	C	.	.	H	α-helix	trans	-66.4	-42.6	176.1	-70.1	-52.5	0	0	0	112	L168 H169 S174 M175	L168-F172 HydrophobicContact CD1-CD2 4.07Å; L168-F172 HydrophobicContact CD1-CE2 3.46Å; L168-F172 VanDerWaalsContact CD1-CE2 3.46Å; L168-F172 HydrophobicContact CD1-CZ 3.79Å; L168-F172 HydrophobicContact CD2-CE2 4.08Å; L168-F172 HydrophobicContact CG-CD2 4.02Å; L168-F172 HydrophobicContact CG-CE2 3.55Å; L168-F172 HydrophobicContact CG-CZ 4.36Å; L168-F172 VanDerWaalsContact O-CD2 3.25Å; L168-F172 WeakPolarHBondContact O-CD2 3.32Å; L168-F172 PolarHBondContact O-N 2.99Å; L168-F172 VanDerWaalsContact O-N 3.08Å; H169-F172 PolarHBondContact O-N 2.78Å; F172-S174 PolarHBondContact O-N 2.75Å; F172-M175 HydrophobicContact CD1-CE 4.07Å; F172-M175 HydrophobicContact CD1-SD 4.29Å; F172-M175 HydrophobicContact CE1-CE 4.43Å; F172-M175 WeakPolarHBondContact O-CB 3.16Å; F172-M175 PolarHBondContact O-N 2.67Å
173	S	95	Very high	93.5	Very high	27 Å²	27	42.9 Å²	42.9	19%	0.189	20%	0.201	C	C	.	.	H	α-helix	trans	-65.1	-18.4	175.6	-62.6	0	0	0	0	113.4	H169 Y170 M175 T176 P180 Y220	H169-S173 WeakPolarHBondContact O-CB 3.35Å; H169-S173 PolarHBondContact O-N 3.13Å; H169-S173 PolarHBondContact O-OG 3.31Å; H169-S173 VanDerWaalsContact O-OG 3.12Å; Y170-S173 PolarHBondContact O-N 3.33Å; S173-M175 VanDerWaalsContact C-N 3.34Å; S173-T176 WeakPolarHBondContact O-CG2 3.48Å; S173-P180 WeakPolarHBondContact O-CD 3.45Å; S173-Y220 VanDerWaalsContact CB-OH 3.24Å; S173-Y220 WeakPolarHBondContact CB-OH 3.36Å; S173-Y220 PolarHBondContact OG-OH 3.41Å
174	S	95.8	Very high	93	Very high	0 Å²	0	43.2 Å²	43.2	0%	0	20%	0.203	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79.3	-13	173.4	-58.4	0	0	0	0	113.2	Y170 L171 F172 T176 W181 T409 F416	Y170-S174 WeakPolarHBondContact O-CB 3.37Å; Y170-S174 PolarHBondContact O-N 2.89Å; Y170-S174 PolarHBondContact O-OG 3.31Å; L171-S174 WeakPolarHBondContact O-CB 3.17Å; L171-S174 PolarHBondContact O-N 3.42Å; F172-S174 PolarHBondContact O-N 2.75Å; S174-T176 PolarHBondContact O-N 2.73Å; S174-W181 WeakPolarHBondContact OG-CH2 3.28Å; S174-T409 WeakPolarHBondContact O-CG2 3.48Å; S174-F416 WeakPolarHBondContact OG-CD2 3.49Å
175	M	93.8	Very high	92.5	Very high	122 Å²	122	51 Å²	51	60%	0.601	24%	0.239	S	C	*	.	S	Bend	trans	-79.7	50.2	-176.7	-60	-172.7	-176.7	0	0	112.6	L171 F172 S173	L171-M175 HydrophobicContact CG-CE 4.35Å; F172-M175 HydrophobicContact CD1-CE 4.07Å; F172-M175 HydrophobicContact CD1-SD 4.29Å; F172-M175 HydrophobicContact CE1-CE 4.43Å; F172-M175 WeakPolarHBondContact O-CB 3.16Å; F172-M175 PolarHBondContact O-N 2.67Å; S173-M175 VanDerWaalsContact C-N 3.34Å
176	T	92.8	Very high	92.1	Very high	61 Å²	61	53.6 Å²	53.6	37%	0.374	25%	0.253	S	S	.	.	S	Bend	trans	-140.8	159.6	-177.9	176.2	0	0	0	0	110.1	S173 S174 E178 T409	S173-T176 WeakPolarHBondContact O-CG2 3.48Å; S174-T176 PolarHBondContact O-N 2.73Å; T176-E178 WeakPolarHBondContact CG2-O 3.25Å; T176-E178 PolarHBondContact OG1-N 2.8Å; T176-E178 PolarHBondContact OG1-O 3.18Å; T176-E178 VanDerWaalsContact OG1-O 3.11Å; T176-T409 VanDerWaalsContact O-CG2 3.22Å; T176-T409 WeakPolarHBondContact O-CG2 3.4Å; T176-T409 PolarHBondContact O-OG1 3.4Å
177	R	87.3	Confident	91.8	Very high	238 Å²	238	58.7 Å²	58.7	90%	0.898	30%	0.295	S	S	*	.	S	Bend	trans	-73.2	-38.9	176.2	-68.1	-174.9	179.2	-179.7	0	112.3
178	E	89.4	Confident	91.5	Very high	116 Å²	116	62.2 Å²	62.2	54%	0.542	31%	0.309	S	S	.	.	S	Bend	trans	-111.6	119.9	173.7	-66.3	-163	172.8	0	0	108.6	T176 K183	T176-E178 WeakPolarHBondContact CG2-O 3.25Å; T176-E178 PolarHBondContact OG1-N 2.8Å; T176-E178 PolarHBondContact OG1-O 3.18Å; T176-E178 VanDerWaalsContact OG1-O 3.11Å; E178-K183 IonicContact OE1-NZ 2.85Å; E178-K183 PolarHBondContact OE1-NZ 3.02Å; E178-K183 IonicContact OE2-NZ 3.84Å; E178-K183 PolarHBondContact OE2-NZ 3.37Å
179	L	92	Very high	91.1	Very high	5 Å²	5	62.9 Å²	62.9	3%	0.026	31%	0.312	C	S	.	.			trans	-66.5	140.8	-179.5	-64.5	173.9	0	0	0	110.7	W181 L182 A403 A412	L179-W181 VanDerWaalsContact C-N 3.26Å; L179-W181 HydrophobicContact CB-CD2 4.31Å; L179-W181 HydrophobicContact CB-CZ2 4.19Å; L179-W181 HydrophobicContact CD1-CZ2 3.94Å; L179-W181 HydrophobicContact CD2-CH2 4.15Å; L179-W181 HydrophobicContact CD2-CZ2 3.77Å; L179-W181 HydrophobicContact CG-CZ2 4.18Å; L179-W181 PolarHBondContact O-N 3.48Å; L179-L182 WeakPolarHBondContact O-CB 3.27Å; L179-L182 PolarHBondContact O-N 2.87Å; L179-L182 VanDerWaalsContact O-N 3.12Å; L179-A403 HydrophobicContact CD1-CB 4.25Å; L179-A412 HydrophobicContact CD1-CB 4.23Å; L179-A412 HydrophobicContact CD2-CB 4.13Å
180	P	91.8	Very high	90.6	Very high	24 Å²	24	63.3 Å²	63.3	16%	0.156	32%	0.317	C	S	.	.	T	Hydrogen-bonded Turn	trans	-69	-24.4	-173.6	24	-29.6	0	0	0	113.3	S173 L182 N186 W188 Y220	S173-P180 WeakPolarHBondContact O-CD 3.45Å; P180-L182 VanDerWaalsContact C-N 3.3Å; P180-L182 PolarHBondContact O-N 2.95Å; P180-N186 PolarHBondContact O-ND2 3.41Å; P180-W188 HydrophobicContact CB-CH2 4.09Å; P180-W188 HydrophobicContact CB-CZ2 4.03Å; P180-Y220 HydrophobicContact CB-CD2 4.11Å; P180-Y220 HydrophobicContact CB-CE2 3.67Å; P180-Y220 HydrophobicContact CG-CE1 4.3Å; P180-Y220 HydrophobicContact CG-CE2 3.84Å
181	W	91.4	Very high	89.9	Confident	5 Å²	5	68.4 Å²	68.4	2%	0.019	36%	0.359	C	S	.	.	T	Hydrogen-bonded Turn	trans	-88.8	18.4	174.8	54	85.1	0	0	0	114	Y170 S174 L179 P216 A217 Y220 P399 A412 F416	Y170-W181 AromaticContact CD1-CE3 3.99Å; Y170-W181 HydrophobicContact CD1-CE3 3.99Å; Y170-W181 AromaticContact CD1-CH2 3.8Å; Y170-W181 HydrophobicContact CD1-CH2 3.8Å; Y170-W181 AromaticContact CD1-CZ3 3.47Å; Y170-W181 HydrophobicContact CD1-CZ3 3.47Å; Y170-W181 VanDerWaalsContact CD1-CZ3 3.47Å; Y170-W181 HydrophobicContact CE1-CD2 4.46Å; Y170-W181 AromaticContact CE1-CE3 3.82Å; Y170-W181 HydrophobicContact CE1-CE3 3.82Å; Y170-W181 HydrophobicContact CE1-CH2 4.42Å; Y170-W181 AromaticContact CE1-CZ3 3.81Å; Y170-W181 HydrophobicContact CE1-CZ3 3.81Å; S174-W181 WeakPolarHBondContact OG-CH2 3.28Å; L179-W181 VanDerWaalsContact C-N 3.26Å; L179-W181 HydrophobicContact CB-CD2 4.31Å; L179-W181 HydrophobicContact CB-CZ2 4.19Å; L179-W181 HydrophobicContact CD1-CZ2 3.94Å; L179-W181 HydrophobicContact CD2-CH2 4.15Å; L179-W181 HydrophobicContact CD2-CZ2 3.77Å; L179-W181 HydrophobicContact CG-CZ2 4.18Å; L179-W181 PolarHBondContact O-N 3.48Å; W181-P216 WeakPolarHBondContact O-CB 3.31Å; W181-A217 HydrophobicContact CB-CB 4.01Å; W181-Y220 HydrophobicContact CB-CD1 4.13Å; W181-Y220 HydrophobicContact CB-CG 4.11Å; W181-Y220 HydrophobicContact CD2-CD1 4.48Å; W181-Y220 AromaticContact CE3-CD1 3.65Å; W181-Y220 HydrophobicContact CE3-CD1 3.65Å; W181-Y220 AromaticContact CE3-CE1 3.47Å; W181-Y220 HydrophobicContact CE3-CE1 3.47Å; W181-Y220 VanDerWaalsContact CE3-CE1 3.47Å; W181-Y220 HydrophobicContact CE3-CG 4.44Å; W181-Y220 HydrophobicContact CZ3-CD1 4.45Å; W181-Y220 AromaticContact CZ3-CE1 3.85Å; W181-Y220 HydrophobicContact CZ3-CE1 3.85Å; W181-P399 HydrophobicContact CD2-CB 4.04Å; W181-P399 HydrophobicContact CG-CB 4.07Å; W181-P399 HydrophobicContact CZ2-CB 4.2Å; W181-P399 PolarHBondContact NE1-O 3.3Å; W181-A412 HydrophobicContact CZ2-CB 4.11Å; W181-F416 AromaticContact CH2-CE2 3.87Å; W181-F416 HydrophobicContact CH2-CE2 3.87Å; W181-F416 HydrophobicContact CZ2-CE2 4Å
182	L	86.6	Confident	89	Confident	59 Å²	59	73.6 Å²	73.6	31%	0.309	39%	0.387	S	S	.	.	S	Bend	trans	-85.4	-35.5	-178.5	-173.3	70.9	0	0	0	113.5	L179 P180 A403	L179-L182 WeakPolarHBondContact O-CB 3.27Å; L179-L182 PolarHBondContact O-N 2.87Å; L179-L182 VanDerWaalsContact O-N 3.12Å; P180-L182 VanDerWaalsContact C-N 3.3Å; P180-L182 PolarHBondContact O-N 2.95Å; L182-A403 HydrophobicContact CD1-CB 3.77Å
183	K	86.1	Confident	88.3	Confident	87 Å²	87	69.3 Å²	69.3	38%	0.378	37%	0.371	S	S	.	.			trans	-133.4	153.8	-169.2	-62.1	174	-176.3	159.3	0	111.7	E178 H185 N186 N189	E178-K183 IonicContact OE1-NZ 2.85Å; E178-K183 PolarHBondContact OE1-NZ 3.02Å; E178-K183 IonicContact OE2-NZ 3.84Å; E178-K183 PolarHBondContact OE2-NZ 3.37Å; K183-H185 VanDerWaalsContact C-N 3.33Å; K183-H185 PolarHBondContact O-N 3.04Å; K183-N186 PolarHBondContact O-ND2 3.38Å; K183-N189 PolarHBondContact O-OD1 3.08Å
184	C	83.4	Confident	87.4	Confident	12 Å²	12	70 Å²	70	8%	0.081	37%	0.374	C	S	.	.	S	Bend	trans	-82.4	8.1	178.1	-81	0	0	0	0	116.2	N189 C193 T194 D195 P216	C184-N189 WeakPolarHBondContact O-CB 3.41Å; C184-N189 VanDerWaalsContact O-CG 3.28Å; C184-N189 PolarHBondContact O-OD1 3.05Å; C184-C193 VanDerWaalsContact CA-SG 3.5Å; C184-C193 HydrophobicContact CB-CB 3.53Å; C184-C193 WeakPolarHBondContact CB-SG 3.3Å; C184-C193 WeakPolarHBondContact SG-CB 3.22Å; C184-C193 CovalentContact SG-SG 2.03Å; C184-C193 PolarHBondContact SG-SG 3.45Å; C184-T194 PolarHBondContact SG-N 3.4Å; C184-D195 WeakPolarHBondContact CB-OD1 3.25Å; C184-D195 PolarHBondContact N-OD1 3.4Å; C184-P216 VanDerWaalsContact SG-CG 3.57Å
185	H	85.1	Confident	86.1	Confident	164 Å²	164	72 Å²	72	76%	0.759	39%	0.385	S	S	*	.			trans	-104.5	38.7	-173	-65.2	-56	0	0	0	114.5	K183	K183-H185 VanDerWaalsContact C-N 3.33Å; K183-H185 PolarHBondContact O-N 3.04Å
186	N	88.5	Confident	84.5	Confident	55 Å²	55	67.4 Å²	67.4	29%	0.294	36%	0.364	S	S	.	.	S	Bend	trans	-105.1	166.8	176.7	-53.7	-71.8	0	0	0	112.2	P180 K183 W188 N189	P180-N186 PolarHBondContact O-ND2 3.41Å; K183-N186 PolarHBondContact O-ND2 3.38Å; N186-W188 HydrophobicContact CB-CD2 3.65Å; N186-W188 HydrophobicContact CB-CE3 3.94Å; N186-W188 HydrophobicContact CB-CG 4.35Å; N186-W188 HydrophobicContact CB-CH2 3.61Å; N186-W188 HydrophobicContact CB-CZ2 3.28Å; N186-W188 HydrophobicContact CB-CZ3 3.92Å; N186-W188 WeakPolarHBondContact ND2-CZ2 3.41Å; N186-W188 PolarHBondContact O-N 3.49Å; N186-N189 WeakPolarHBondContact CA-OD1 3.23Å; N186-N189 VanDerWaalsContact CB-OD1 3.23Å; N186-N189 WeakPolarHBondContact CB-OD1 3.33Å; N186-N189 PolarHBondContact N-OD1 3.01Å; N186-N189 PolarHBondContact ND2-OD1 2.86Å; N186-N189 VanDerWaalsContact ND2-OD1 3.11Å; N186-N189 PolarHBondContact O-N 2.81Å; N186-N189 VanDerWaalsContact O-N 3.08Å
187	A	90.5	Very high	82.8	Confident	108 Å²	108	72.2 Å²	72.2	89%	0.893	38%	0.382	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.9	-24.6	-178.2	0	0	0	0	0	114.3
188	W	88.9	Confident	81.3	Confident	73 Å²	73	67.2 Å²	67.2	28%	0.277	37%	0.368	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.2	-10.1	178.4	54.7	82.3	0	0	0	113.6	P180 N186 Y220 R223	P180-W188 HydrophobicContact CB-CH2 4.09Å; P180-W188 HydrophobicContact CB-CZ2 4.03Å; N186-W188 HydrophobicContact CB-CD2 3.65Å; N186-W188 HydrophobicContact CB-CE3 3.94Å; N186-W188 HydrophobicContact CB-CG 4.35Å; N186-W188 HydrophobicContact CB-CH2 3.61Å; N186-W188 HydrophobicContact CB-CZ2 3.28Å; N186-W188 HydrophobicContact CB-CZ3 3.92Å; N186-W188 WeakPolarHBondContact ND2-CZ2 3.41Å; N186-W188 PolarHBondContact O-N 3.49Å; W188-Y220 HydrophobicContact CD2-CD2 4.42Å; W188-Y220 AromaticContact CE2-CD2 3.59Å; W188-Y220 HydrophobicContact CH2-CD2 4.3Å; W188-Y220 HydrophobicContact CH2-CE2 4.22Å; W188-Y220 AromaticContact CZ2-CD2 3.52Å; W188-Y220 HydrophobicContact CZ2-CD2 3.52Å; W188-Y220 AromaticContact CZ2-CE2 3.88Å; W188-Y220 HydrophobicContact CZ2-CE2 3.88Å; W188-Y220 AromaticContact NE1-CD2 3.72Å; W188-R223 HydrophobicContact CB-CB 4.28Å; W188-R223 WeakPolarHBondContact O-CB 3.45Å; W188-R223 VanDerWaalsContact O-CD 3.25Å; W188-R223 WeakPolarHBondContact O-CD 3.36Å
189	N	89.6	Confident	79.8	Confident	24 Å²	24	62.9 Å²	62.9	13%	0.128	35%	0.349	C	S	.	.			trans	-75.6	146.6	-174.5	-71.9	122.2	0	0	0	112.4	K183 C184 N186 C193 E219	K183-N189 PolarHBondContact O-OD1 3.08Å; C184-N189 WeakPolarHBondContact O-CB 3.41Å; C184-N189 VanDerWaalsContact O-CG 3.28Å; C184-N189 PolarHBondContact O-OD1 3.05Å; N186-N189 WeakPolarHBondContact CA-OD1 3.23Å; N186-N189 VanDerWaalsContact CB-OD1 3.23Å; N186-N189 WeakPolarHBondContact CB-OD1 3.33Å; N186-N189 PolarHBondContact N-OD1 3.01Å; N186-N189 PolarHBondContact ND2-OD1 2.86Å; N186-N189 VanDerWaalsContact ND2-OD1 3.11Å; N186-N189 PolarHBondContact O-N 2.81Å; N186-N189 VanDerWaalsContact O-N 3.08Å; N189-C193 HydrophobicContact CB-CB 4.28Å; N189-C193 PolarHBondContact ND2-SG 3.37Å; N189-C193 VanDerWaalsContact ND2-SG 3.41Å; N189-E219 WeakPolarHBondContact CA-OE2 3.33Å; N189-E219 WeakPolarHBondContact CB-OE2 3.41Å; N189-E219 PolarHBondContact ND2-OE2 2.97Å
190	S	85.7	Confident	77.9	Confident	23 Å²	23	68.1 Å²	68.1	16%	0.161	38%	0.376	C	S	.	.			trans	-86.5	161.8	173.3	87.8	0	0	0	0	111.5	N192 C193 E219 R223	S190-N192 PolarHBondContact O-N 2.91Å; S190-N192 VanDerWaalsContact O-N 3.15Å; S190-N192 PolarHBondContact OG-N 3.28Å; S190-N192 VanDerWaalsContact OG-N 3.12Å; S190-C193 VanDerWaalsContact O-CB 3.29Å; S190-C193 WeakPolarHBondContact O-CB 3.37Å; S190-C193 PolarHBondContact O-N 3.44Å; S190-C193 VanDerWaalsContact O-N 3.08Å; S190-C193 PolarHBondContact OG-N 3.34Å; S190-E219 WeakPolarHBondContact CB-OE1 3.46Å; S190-E219 PolarHBondContact N-OE1 3.13Å; S190-E219 PolarHBondContact N-OE2 3.08Å; S190-E219 PolarHBondContact OG-OE1 3.07Å; S190-R223 VanDerWaalsContact CB-CZ 3.48Å
191	A	81	Confident	76	Confident	109 Å²	109	69.9 Å²	69.9	90%	0.901	40%	0.399	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.8	-18.1	172.4	0	0	0	0	0	113.1
192	N	78.8	Confident	73.9	Confident	126 Å²	126	74.7 Å²	74.7	67%	0.674	43%	0.434	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.5	-15.1	178	-68.6	-5.8	0	0	0	112	S190 T194 I214	S190-N192 PolarHBondContact O-N 2.91Å; S190-N192 VanDerWaalsContact O-N 3.15Å; S190-N192 PolarHBondContact OG-N 3.28Å; S190-N192 VanDerWaalsContact OG-N 3.12Å; N192-T194 PolarHBondContact O-N 3.5Å; N192-I214 VanDerWaalsContact C-CG2 3.47Å; N192-I214 HydrophobicContact CB-CG2 4.38Å; N192-I214 WeakPolarHBondContact O-CG2 3.36Å
193	C	81.7	Confident	72.2	Confident	18 Å²	18	75.9 Å²	75.9	12%	0.122	44%	0.443	C	S	.	.			trans	-53.7	125.1	-176.7	-165.1	0	0	0	0	111.2	C184 N189 S190 I214 E219	C184-C193 VanDerWaalsContact CA-SG 3.5Å; C184-C193 HydrophobicContact CB-CB 3.53Å; C184-C193 WeakPolarHBondContact CB-SG 3.3Å; C184-C193 WeakPolarHBondContact SG-CB 3.22Å; C184-C193 CovalentContact SG-SG 2.03Å; C184-C193 PolarHBondContact SG-SG 3.45Å; N189-C193 HydrophobicContact CB-CB 4.28Å; N189-C193 PolarHBondContact ND2-SG 3.37Å; N189-C193 VanDerWaalsContact ND2-SG 3.41Å; S190-C193 VanDerWaalsContact O-CB 3.29Å; S190-C193 WeakPolarHBondContact O-CB 3.37Å; S190-C193 PolarHBondContact O-N 3.44Å; S190-C193 VanDerWaalsContact O-N 3.08Å; S190-C193 PolarHBondContact OG-N 3.34Å; C193-I214 WeakPolarHBondContact CA-O 3.5Å; C193-E219 VanDerWaalsContact CB-OE2 3.27Å; C193-E219 WeakPolarHBondContact CB-OE2 3.45Å; C193-E219 PolarHBondContact SG-OE2 3.16Å; C193-E219 VanDerWaalsContact SG-OE2 3.35Å
194	T	74.8	Confident	70.5	Confident	42 Å²	42	73.7 Å²	73.7	26%	0.258	44%	0.435	S	S	.	.			trans	-116.2	124.6	-179.3	44.5	0	0	0	0	109.5	C184 N192 I214	C184-T194 PolarHBondContact SG-N 3.4Å; N192-T194 PolarHBondContact O-N 3.5Å; T194-I214 HydrophobicContact CG2-CG2 4.3Å; T194-I214 PolarHBondContact N-O 2.91Å; T194-I214 WeakPolarHBondContact OG1-CG2 3.47Å
195	D	69.1	Low	68.7	Low	42 Å²	42	75.3 Å²	75.3	23%	0.225	45%	0.454	C	S	.	.			trans	-61.5	136.9	174.3	-75.5	-33	0	0	0	109.7	C184 E197 H198	C184-D195 WeakPolarHBondContact CB-OD1 3.25Å; C184-D195 PolarHBondContact N-OD1 3.4Å; D195-E197 PolarHBondContact O-N 2.98Å; D195-H198 PolarHBondContact O-N 2.92Å
196	P	60.8	Low	66.9	Low	25 Å²	25	76.6 Å²	76.6	16%	0.162	47%	0.467	C	S	.	.	T	Hydrogen-bonded Turn	trans	-60.2	-18.5	-173	-24.8	34.5	0	0	0	114.7	P216 H379	P196-P216 HydrophobicContact CG-CG 4.27Å; P196-H379 WeakPolarHBondContact CB-CE1 3.44Å; P196-H379 PolarHBondContact O-CE1 2.88Å; P196-H379 PolarHBondContact O-ND1 2.95Å
197	E	57.2	Low	65	Low	161 Å²	161	74.8 Å²	74.8	75%	0.752	46%	0.461	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.4	-19.5	176.2	-62.6	-170.1	161.1	0	0	113.8	D195	D195-E197 PolarHBondContact O-N 2.98Å
198	H	54.2	Low	63.2	Low	134 Å²	134	72.2 Å²	72.2	62%	0.62	43%	0.434	S	S	*	.	S	Bend	trans	-102.7	2.1	-176.5	-66	88.9	0	0	0	113.4	D195 N200	D195-H198 PolarHBondContact O-N 2.92Å; H198-N200 VanDerWaalsContact C-N 3.31Å; H198-N200 PolarHBondContact O-N 3.02Å
199	I	58	Low	61.5	Low	25 Å²	25	69.6 Å²	69.6	13%	0.128	42%	0.424	C	S	.	.			trans	-77	85.3	179.1	-55.8	175.8	0	0	0	108.8	L204 Y209	I199-L204 HydrophobicContact CG2-CD1 3.68Å; I199-Y209 HydrophobicContact CD1-CE2 3.51Å; I199-Y209 HydrophobicContact CG2-CD2 4.47Å; I199-Y209 HydrophobicContact CG2-CE2 4.07Å
200	N	52.9	Low	59.6	Low	114 Å²	114	70 Å²	70	61%	0.61	43%	0.431	S	S	*	.			trans	-71.3	139.6	163.6	-77.2	-29	0	0	0	108.9	H198 S202 V203	H198-N200 VanDerWaalsContact C-N 3.31Å; H198-N200 PolarHBondContact O-N 3.02Å; N200-S202 PolarHBondContact O-N 3.41Å; N200-V203 PolarHBondContact O-N 3.36Å
201	G	51.3	Low	57.7	Low	62 Å²	62	74.4 Å²	74.4	64%	0.639	45%	0.448	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.3	-6.2	-178.7	0	0	0	0	0	115.8
202	S	47.1	Very low	56.4	Low	105 Å²	105	74.5 Å²	74.5	73%	0.734	43%	0.425	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.5	-19.5	170.7	56.2	0	0	0	0	114.7	N200	N200-S202 PolarHBondContact O-N 3.41Å
203	V	50.4	Low	55.6	Low	85 Å²	85	70.6 Å²	70.6	52%	0.515	40%	0.402	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.9	-25.2	177.4	-177.5	0	0	0	0	111.3	N200 G205	N200-V203 PolarHBondContact O-N 3.36Å; V203-G205 PolarHBondContact O-N 3.41Å; V203-G205 VanDerWaalsContact O-N 3.1Å
204	L	50.8	Low	55.1	Low	40 Å²	40	71.7 Å²	71.7	21%	0.209	41%	0.407	C	S	.	.			trans	-76.5	91.6	163.8	-74.3	101.6	0	0	0	108.7	I199 Y209	I199-L204 HydrophobicContact CG2-CD1 3.68Å; L204-Y209 HydrophobicContact CD1-CD2 4.16Å; L204-Y209 HydrophobicContact CD2-CD2 4.32Å
205	G	46.8	Very low	55.4	Low	46 Å²	46	70.2 Å²	70.2	47%	0.474	40%	0.398	S	S	.	.			trans	-57.1	-167.8	157.4	0	0	0	0	0	111.2	V203 G207	V203-G205 PolarHBondContact O-N 3.41Å; V203-G205 VanDerWaalsContact O-N 3.1Å; G205-G207 PolarHBondContact O-N 2.86Å
206	N	46.2	Very low	56.3	Low	191 Å²	191	68.3 Å²	68.3	100%	1.021	39%	0.388	S	S	*	.	S	Bend	trans	-55.5	9.7	179.4	-90.6	-10.1	0	0	0	116.9
207	G	50	Low	57.6	Low	17 Å²	17	67.2 Å²	67.2	18%	0.175	38%	0.38	C	S	.	.	S	Bend	trans	-103.9	161.1	174.3	0	0	0	0	0	114	G205	G205-G207 PolarHBondContact O-N 2.86Å
208	T	51.8	Low	59	Low	55 Å²	55	59.6 Å²	59.6	34%	0.337	35%	0.345	S	S	.	.			trans	-81.5	149.7	-177.1	51.4	0	0	0	0	112.6	A210 K211 Y212 D385	T208-A210 VanDerWaalsContact C-N 3.35Å; T208-A210 PolarHBondContact O-N 2.79Å; T208-K211 VanDerWaalsContact O-CB 3.29Å; T208-K211 WeakPolarHBondContact O-CB 3.3Å; T208-K211 PolarHBondContact O-N 3.12Å; T208-K211 WeakPolarHBondContact OG1-CB 3.41Å; T208-Y212 WeakPolarHBondContact O-CD2 3.46Å; T208-D385 WeakPolarHBondContact CB-OD1 3.35Å; T208-D385 WeakPolarHBondContact CG2-OD1 3.35Å
209	Y	53.4	Low	60.7	Low	17 Å²	17	53.7 Å²	53.7	7%	0.067	32%	0.318	C	S	.	.	H	α-helix	trans	-51.9	-47	-179.4	-172.5	-97.7	0	0	0	112.8	I199 L204 K211 T215 H379 V381 V386 E400	I199-Y209 HydrophobicContact CD1-CE2 3.51Å; I199-Y209 HydrophobicContact CG2-CD2 4.47Å; I199-Y209 HydrophobicContact CG2-CE2 4.07Å; L204-Y209 HydrophobicContact CD1-CD2 4.16Å; L204-Y209 HydrophobicContact CD2-CD2 4.32Å; Y209-K211 VanDerWaalsContact C-N 3.28Å; Y209-K211 PolarHBondContact O-N 3.44Å; Y209-T215 HydrophobicContact CE1-CG2 3.99Å; Y209-H379 HydrophobicContact CE2-CB 4.33Å; Y209-V381 HydrophobicContact CD2-CG1 3.62Å; Y209-V381 HydrophobicContact CE2-CG1 4.18Å; Y209-V381 HydrophobicContact CG-CG1 4.02Å; Y209-V386 HydrophobicContact CD1-CG1 4.18Å; Y209-E400 PolarHBondContact OH-OE1 3.46Å
210	A	48.8	Very low	62.3	Low	32 Å²	32	53.1 Å²	53.1	26%	0.264	31%	0.314	S	S	.	.	H	α-helix	trans	-63.3	-26.9	175.4	0	0	0	0	0	114.6	T208 Y212 D385 T388	T208-A210 VanDerWaalsContact C-N 3.35Å; T208-A210 PolarHBondContact O-N 2.79Å; A210-Y212 VanDerWaalsContact C-N 3.28Å; A210-Y212 PolarHBondContact O-N 2.86Å; A210-D385 WeakPolarHBondContact CB-O 3.36Å; A210-D385 PolarHBondContact N-O 2.92Å; A210-D385 VanDerWaalsContact N-O 3.16Å; A210-T388 HydrophobicContact CB-CG2 3.93Å
211	K	47.6	Very low	64.2	Low	117 Å²	117	47.8 Å²	47.8	51%	0.509	29%	0.285	S	S	.	.	H	α-helix	trans	-69.2	-28.3	-175	-175.4	172.5	-176.1	177	0	112.6	T208 Y209	T208-K211 VanDerWaalsContact O-CB 3.29Å; T208-K211 WeakPolarHBondContact O-CB 3.3Å; T208-K211 PolarHBondContact O-N 3.12Å; T208-K211 WeakPolarHBondContact OG1-CB 3.41Å; Y209-K211 VanDerWaalsContact C-N 3.28Å; Y209-K211 PolarHBondContact O-N 3.44Å
212	Y	52.2	Low	66	Low	110 Å²	110	46.4 Å²	46.4	43%	0.431	26%	0.262	S	S	.	.	H	α-helix	trans	-92.8	-12.2	-173.2	-65.1	-76.9	0	0	0	114.4	T208 A210 I214	T208-Y212 WeakPolarHBondContact O-CD2 3.46Å; A210-Y212 VanDerWaalsContact C-N 3.28Å; A210-Y212 PolarHBondContact O-N 2.86Å; Y212-I214 VanDerWaalsContact CB-CD1 3.48Å; Y212-I214 HydrophobicContact CG-CD1 4.24Å; Y212-I214 WeakPolarHBondContact O-CG1 3.15Å; Y212-I214 PolarHBondContact O-N 2.85Å
213	K	62.4	Low	68.1	Low	44 Å²	44	45.4 Å²	45.4	19%	0.191	24%	0.242	C	C	.	.			trans	44.2	35.1	175.2	-62.4	-170.7	-177.8	174.3	0	114.6	T215 A218 E222 D553	K213-T215 VanDerWaalsContact C-N 3.3Å; K213-A218 HydrophobicContact CB-CB 3.89Å; K213-A218 HydrophobicContact CG-CB 4.41Å; K213-E222 VanDerWaalsContact CD-CD 3.41Å; K213-E222 WeakPolarHBondContact CD-OE1 3.09Å; K213-E222 WeakPolarHBondContact CD-OE2 3.28Å; K213-E222 WeakPolarHBondContact CE-OE1 3.42Å; K213-E222 IonicContact NZ-OE1 3.8Å; K213-E222 PolarHBondContact NZ-OE1 3.39Å; K213-D553 IonicContact NZ-OD1 2.79Å; K213-D553 IonicContact NZ-OD2 3.68Å; K213-D553 PolarHBondContact NZ-OD2 3.33Å
214	I	71.6	Confident	70	Confident	42 Å²	42	41.9 Å²	41.9	22%	0.215	22%	0.224	C	C	.	.			trans	-88.3	-5.3	-173.5	-37.9	176.8	0	0	0	111.6	N192 C193 T194 Y212	N192-I214 VanDerWaalsContact C-CG2 3.47Å; N192-I214 HydrophobicContact CB-CG2 4.38Å; N192-I214 WeakPolarHBondContact O-CG2 3.36Å; C193-I214 WeakPolarHBondContact CA-O 3.5Å; T194-I214 HydrophobicContact CG2-CG2 4.3Å; T194-I214 PolarHBondContact N-O 2.91Å; T194-I214 WeakPolarHBondContact OG1-CG2 3.47Å; Y212-I214 VanDerWaalsContact CB-CD1 3.48Å; Y212-I214 HydrophobicContact CG-CD1 4.24Å; Y212-I214 WeakPolarHBondContact O-CG1 3.15Å; Y212-I214 PolarHBondContact O-N 2.85Å
215	T	80.8	Confident	72	Confident	11 Å²	11	40.2 Å²	40.2	7%	0.067	22%	0.215	C	C	.	.	S	Bend	trans	-71.5	148.9	-178.9	61	0	0	0	0	111.1	Y209 K213 A217 A218 E219 E400	Y209-T215 HydrophobicContact CE1-CG2 3.99Å; K213-T215 VanDerWaalsContact C-N 3.3Å; T215-A217 PolarHBondContact O-N 2.9Å; T215-A217 VanDerWaalsContact O-N 3.15Å; T215-A218 PolarHBondContact O-N 3.37Å; T215-A218 VanDerWaalsContact O-N 3.14Å; T215-A218 WeakPolarHBondContact OG1-CB 3.18Å; T215-A218 PolarHBondContact OG1-N 3.38Å; T215-A218 VanDerWaalsContact OG1-N 3.15Å; T215-E219 PolarHBondContact O-N 2.93Å; T215-E400 WeakPolarHBondContact CG2-OE1 3.43Å
216	P	87.3	Confident	74.1	Confident	2 Å²	2	38.3 Å²	38.3	1%	0.013	19%	0.194	C	C	.	.	H	α-helix	trans	-51.5	-37.6	173.6	-23.2	27.2	0	0	0	113.9	W181 C184 P196 Y220	W181-P216 WeakPolarHBondContact O-CB 3.31Å; C184-P216 VanDerWaalsContact SG-CG 3.57Å; P196-P216 HydrophobicContact CG-CG 4.27Å; P216-Y220 VanDerWaalsContact O-CB 3.27Å; P216-Y220 WeakPolarHBondContact O-CB 3.32Å; P216-Y220 PolarHBondContact O-N 2.67Å
217	A	88.6	Confident	76.3	Confident	1 Å²	1	30.9 Å²	30.9	1%	0.008	15%	0.153	C	C	.	.	H	α-helix	trans	-71.2	-41.8	179.8	0	0	0	0	0	113.2	W181 T215 Y220 Y221 I396 E400	W181-A217 HydrophobicContact CB-CB 4.01Å; T215-A217 PolarHBondContact O-N 2.9Å; T215-A217 VanDerWaalsContact O-N 3.15Å; A217-Y220 PolarHBondContact O-N 2.87Å; A217-Y221 PolarHBondContact O-N 3.28Å; A217-I396 HydrophobicContact CB-CG2 4.31Å; A217-I396 WeakPolarHBondContact CB-O 3.32Å; A217-E400 HydrophobicContact CB-CB 3.83Å
218	A	86.4	Confident	78.1	Confident	2 Å²	2	30.8 Å²	30.8	2%	0.017	15%	0.148	C	C	.	.	H	α-helix	trans	-63.4	-46.3	175.4	0	0	0	0	0	111	K213 T215 Y220 Y221 E222 I396	K213-A218 HydrophobicContact CB-CB 3.89Å; K213-A218 HydrophobicContact CG-CB 4.41Å; T215-A218 PolarHBondContact O-N 3.37Å; T215-A218 VanDerWaalsContact O-N 3.14Å; T215-A218 WeakPolarHBondContact OG1-CB 3.18Å; T215-A218 PolarHBondContact OG1-N 3.38Å; T215-A218 VanDerWaalsContact OG1-N 3.15Å; A218-Y220 VanDerWaalsContact C-N 3.33Å; A218-Y220 PolarHBondContact O-N 3.19Å; A218-Y221 PolarHBondContact O-N 3.46Å; A218-E222 WeakPolarHBondContact O-CG 3.08Å; A218-E222 PolarHBondContact O-N 2.93Å; A218-I396 HydrophobicContact CB-CD1 4.31Å; A218-I396 HydrophobicContact CB-CG2 3.74Å
219	E	89.5	Confident	79.8	Confident	10 Å²	10	32.9 Å²	32.9	5%	0.047	15%	0.154	C	C	.	.	H	α-helix	trans	-66.7	-34.8	176.8	-70.3	-159.9	162.8	0	0	112.4	N189 S190 C193 T215 R223 G224	N189-E219 WeakPolarHBondContact CA-OE2 3.33Å; N189-E219 WeakPolarHBondContact CB-OE2 3.41Å; N189-E219 PolarHBondContact ND2-OE2 2.97Å; S190-E219 WeakPolarHBondContact CB-OE1 3.46Å; S190-E219 PolarHBondContact N-OE1 3.13Å; S190-E219 PolarHBondContact N-OE2 3.08Å; S190-E219 PolarHBondContact OG-OE1 3.07Å; C193-E219 VanDerWaalsContact CB-OE2 3.27Å; C193-E219 WeakPolarHBondContact CB-OE2 3.45Å; C193-E219 PolarHBondContact SG-OE2 3.16Å; C193-E219 VanDerWaalsContact SG-OE2 3.35Å; T215-E219 PolarHBondContact O-N 2.93Å; E219-R223 WeakPolarHBondContact O-CA 3.11Å; E219-R223 VanDerWaalsContact O-CB 3.25Å; E219-R223 WeakPolarHBondContact O-CB 3.25Å; E219-R223 PolarHBondContact O-N 3.18Å; E219-G224 PolarHBondContact O-N 3.46Å; E219-G224 VanDerWaalsContact O-N 3.16Å
220	Y	92.9	Very high	81.5	Confident	13 Å²	13	36.5 Å²	36.5	5%	0.051	17%	0.172	C	C	.	.	I	π-helix	trans	-60.7	-47	172.5	-178.5	-106	0	0	0	111.2	Y170 S173 P180 W181 W188 P216 A217 A218 G224 V225	Y170-Y220 HydrophobicContact CD1-CE1 4.24Å; Y170-Y220 AromaticContact CE1-CD1 3.81Å; Y170-Y220 HydrophobicContact CE1-CD1 3.81Å; Y170-Y220 AromaticContact CE1-CE1 3.64Å; Y170-Y220 HydrophobicContact CE1-CE1 3.64Å; Y170-Y220 HydrophobicContact CE2-CE1 4.43Å; Y170-Y220 AromaticContact CZ-CD1 3.81Å; Y170-Y220 AromaticContact CZ-CE1 3.74Å; Y170-Y220 WeakPolarHBondContact OH-CD1 3.25Å; S173-Y220 VanDerWaalsContact CB-OH 3.24Å; S173-Y220 WeakPolarHBondContact CB-OH 3.36Å; S173-Y220 PolarHBondContact OG-OH 3.41Å; P180-Y220 HydrophobicContact CB-CD2 4.11Å; P180-Y220 HydrophobicContact CB-CE2 3.67Å; P180-Y220 HydrophobicContact CG-CE1 4.3Å; P180-Y220 HydrophobicContact CG-CE2 3.84Å; W181-Y220 HydrophobicContact CB-CD1 4.13Å; W181-Y220 HydrophobicContact CB-CG 4.11Å; W181-Y220 HydrophobicContact CD2-CD1 4.48Å; W181-Y220 AromaticContact CE3-CD1 3.65Å; W181-Y220 HydrophobicContact CE3-CD1 3.65Å; W181-Y220 AromaticContact CE3-CE1 3.47Å; W181-Y220 HydrophobicContact CE3-CE1 3.47Å; W181-Y220 VanDerWaalsContact CE3-CE1 3.47Å; W181-Y220 HydrophobicContact CE3-CG 4.44Å; W181-Y220 HydrophobicContact CZ3-CD1 4.45Å; W181-Y220 AromaticContact CZ3-CE1 3.85Å; W181-Y220 HydrophobicContact CZ3-CE1 3.85Å; W188-Y220 HydrophobicContact CD2-CD2 4.42Å; W188-Y220 AromaticContact CE2-CD2 3.59Å; W188-Y220 HydrophobicContact CH2-CD2 4.3Å; W188-Y220 HydrophobicContact CH2-CE2 4.22Å; W188-Y220 AromaticContact CZ2-CD2 3.52Å; W188-Y220 HydrophobicContact CZ2-CD2 3.52Å; W188-Y220 AromaticContact CZ2-CE2 3.88Å; W188-Y220 HydrophobicContact CZ2-CE2 3.88Å; W188-Y220 AromaticContact NE1-CD2 3.72Å; P216-Y220 VanDerWaalsContact O-CB 3.27Å; P216-Y220 WeakPolarHBondContact O-CB 3.32Å; P216-Y220 PolarHBondContact O-N 2.67Å; A217-Y220 PolarHBondContact O-N 2.87Å; A218-Y220 VanDerWaalsContact C-N 3.33Å; A218-Y220 PolarHBondContact O-N 3.19Å; Y220-G224 CarbonylContact O-C 3.47Å; Y220-G224 WeakPolarHBondContact O-CA 3.2Å; Y220-G224 PolarHBondContact O-N 2.83Å; Y220-V225 HydrophobicContact CD1-CG2 3.96Å; Y220-V225 HydrophobicContact CE1-CG2 3.54Å; Y220-V225 HydrophobicContact CE2-CG2 4.43Å; Y220-V225 PolarHBondContact O-N 2.8Å
221	Y	92.4	Very high	83.4	Confident	1 Å²	1	35.5 Å²	35.5	0%	0.004	16%	0.163	C	C	.	.	I	π-helix	trans	-64.4	-51.4	177.8	-179.4	-115.9	0	0	0	112.5	W166 Y170 A217 A218 L226 F395 I396	W166-Y221 HydrophobicContact CE3-CE2 4.49Å; W166-Y221 WeakPolarHBondContact CZ3-OH 3.41Å; Y170-Y221 HydrophobicContact CE2-CD2 4.22Å; Y170-Y221 WeakPolarHBondContact OH-CB 3.43Å; A217-Y221 PolarHBondContact O-N 3.28Å; A218-Y221 PolarHBondContact O-N 3.46Å; Y221-L226 HydrophobicContact CD1-CD1 4.09Å; Y221-L226 HydrophobicContact CD2-CD1 4.4Å; Y221-L226 HydrophobicContact CD2-CG 4.44Å; Y221-L226 HydrophobicContact CE1-CD1 3.57Å; Y221-L226 HydrophobicContact CE2-CD1 3.92Å; Y221-L226 HydrophobicContact CE2-CG 4.15Å; Y221-L226 HydrophobicContact CG-CD1 4.5Å; Y221-L226 VanDerWaalsContact CZ-CD1 3.49Å; Y221-L226 WeakPolarHBondContact O-CB 3.06Å; Y221-L226 WeakPolarHBondContact O-CG 3.12Å; Y221-L226 PolarHBondContact O-N 3.43Å; Y221-F395 HydrophobicContact CD2-CB 3.55Å; Y221-F395 HydrophobicContact CD2-CG 4.3Å; Y221-F395 HydrophobicContact CE2-CB 3.62Å; Y221-F395 HydrophobicContact CE2-CD2 4.14Å; Y221-F395 AromaticContact CE2-CG 3.98Å; Y221-F395 HydrophobicContact CE2-CG 3.98Å; Y221-F395 HydrophobicContact CG-CB 4.18Å; Y221-I396 HydrophobicContact CD1-CD1 3.82Å; Y221-I396 HydrophobicContact CD1-CG1 3.87Å; Y221-I396 HydrophobicContact CG-CD1 4.48Å; Y221-I396 HydrophobicContact CG-CG1 4.06Å
222	E	89.6	Confident	85.3	Confident	33 Å²	33	38.7 Å²	38.7	15%	0.154	18%	0.177	C	C	.	.	I	π-helix	trans	-78.4	-42.3	-172.5	-64.9	-161.5	142.6	0	0	113.7	K213 A218 H227 L228	K213-E222 VanDerWaalsContact CD-CD 3.41Å; K213-E222 WeakPolarHBondContact CD-OE1 3.09Å; K213-E222 WeakPolarHBondContact CD-OE2 3.28Å; K213-E222 WeakPolarHBondContact CE-OE1 3.42Å; K213-E222 IonicContact NZ-OE1 3.8Å; K213-E222 PolarHBondContact NZ-OE1 3.39Å; A218-E222 WeakPolarHBondContact O-CG 3.08Å; A218-E222 PolarHBondContact O-N 2.93Å; E222-H227 CarbonylContact O-C 3.43Å; E222-H227 WeakPolarHBondContact O-CA 3.18Å; E222-H227 PolarHBondContact O-N 2.92Å; E222-L228 PolarHBondContact O-N 2.99Å
223	R	90.8	Very high	87	Confident	84 Å²	84	33.4 Å²	33.4	32%	0.317	16%	0.156	S	C	.	.	I	π-helix	trans	-97.3	-40.9	-176	-59.7	-175.7	163.6	-143.9	-2.8	112.4	W188 S190 E219 H227 H229	W188-R223 HydrophobicContact CB-CB 4.28Å; W188-R223 WeakPolarHBondContact O-CB 3.45Å; W188-R223 VanDerWaalsContact O-CD 3.25Å; W188-R223 WeakPolarHBondContact O-CD 3.36Å; S190-R223 VanDerWaalsContact CB-CZ 3.48Å; E219-R223 WeakPolarHBondContact O-CA 3.11Å; E219-R223 VanDerWaalsContact O-CB 3.25Å; E219-R223 WeakPolarHBondContact O-CB 3.25Å; E219-R223 PolarHBondContact O-N 3.18Å; R223-H227 PolarHBondContact O-CD2 2.93Å; R223-H227 PolarHBondContact O-NE2 2.67Å; R223-H229 HydrophobicContact CG-CB 4.35Å
224	G	89.9	Confident	88.3	Confident	12 Å²	12	32 Å²	32	12%	0.124	15%	0.15	C	C	.	.	I	π-helix	trans	-75.6	-53.6	-179.6	0	0	0	0	0	113.2	E219 Y220 H227	E219-G224 PolarHBondContact O-N 3.46Å; E219-G224 VanDerWaalsContact O-N 3.16Å; Y220-G224 CarbonylContact O-C 3.47Å; Y220-G224 WeakPolarHBondContact O-CA 3.2Å; Y220-G224 PolarHBondContact O-N 2.83Å; G224-H227 PolarHBondContact O-CD2 3.47Å; G224-H227 VanDerWaalsContact O-CD2 3.24Å; G224-H227 PolarHBondContact O-NE2 3.5Å
225	V	92.9	Very high	89.2	Confident	4 Å²	4	35.6 Å²	35.6	2%	0.024	17%	0.166	C	C	.	.	I	π-helix	trans	-86.5	-53.7	-173.3	-179	0	0	0	0	111.4	Y170 Y220 L244	Y170-V225 HydrophobicContact CE2-CG1 4.44Å; Y170-V225 HydrophobicContact CE2-CG2 3.96Å; Y220-V225 HydrophobicContact CD1-CG2 3.96Å; Y220-V225 HydrophobicContact CE1-CG2 3.54Å; Y220-V225 HydrophobicContact CE2-CG2 4.43Å; Y220-V225 PolarHBondContact O-N 2.8Å; V225-L244 HydrophobicContact CG1-CD1 4.38Å; V225-L244 HydrophobicContact CG1-CD2 3.99Å
226	L	91.6	Very high	89.7	Confident	7 Å²	7	38.4 Å²	38.4	4%	0.037	18%	0.181	C	C	.	.	S	Bend	trans	-86.1	-26.1	-173.6	-65.5	-178.8	0	0	0	114.3	W166 Y221 L228 I473	W166-L226 HydrophobicContact CZ2-CD2 3.67Å; Y221-L226 HydrophobicContact CD1-CD1 4.09Å; Y221-L226 HydrophobicContact CD2-CD1 4.4Å; Y221-L226 HydrophobicContact CD2-CG 4.44Å; Y221-L226 HydrophobicContact CE1-CD1 3.57Å; Y221-L226 HydrophobicContact CE2-CD1 3.92Å; Y221-L226 HydrophobicContact CE2-CG 4.15Å; Y221-L226 HydrophobicContact CG-CD1 4.5Å; Y221-L226 VanDerWaalsContact CZ-CD1 3.49Å; Y221-L226 WeakPolarHBondContact O-CB 3.06Å; Y221-L226 WeakPolarHBondContact O-CG 3.12Å; Y221-L226 PolarHBondContact O-N 3.43Å; L226-L228 HydrophobicContact CB-CB 4.39Å; L226-L228 PolarHBondContact O-N 2.99Å; L226-I473 HydrophobicContact CD1-CB 4.33Å; L226-I473 HydrophobicContact CD1-CG1 4.5Å
227	H	91.4	Very high	89.7	Confident	34 Å²	34	40.5 Å²	40.5	16%	0.157	19%	0.192	C	C	.	.			trans	54.4	34.4	-169.5	-77.6	-124.4	0	0	0	113.2	E222 R223 G224 H229 E230 R241	E222-H227 CarbonylContact O-C 3.43Å; E222-H227 WeakPolarHBondContact O-CA 3.18Å; E222-H227 PolarHBondContact O-N 2.92Å; R223-H227 PolarHBondContact O-CD2 2.93Å; R223-H227 PolarHBondContact O-NE2 2.67Å; G224-H227 PolarHBondContact O-CD2 3.47Å; G224-H227 VanDerWaalsContact O-CD2 3.24Å; G224-H227 PolarHBondContact O-NE2 3.5Å; H227-H229 PolarHBondContact O-N 3.02Å; H227-H229 VanDerWaalsContact O-N 3.16Å; H227-E230 HydrophobicContact CB-CG 4.46Å; H227-E230 IonicContact CE1-OE1 3.26Å; H227-E230 IonicContact CG-OE1 3.05Å; H227-E230 IonicContact ND1-OE1 3.91Å; H227-E230 PolarHBondContact ND1-OE1 3.39Å; H227-E230 IonicContact ND1-OE2 2.69Å; H227-E230 WeakPolarHBondContact O-CB 3.39Å; H227-E230 PolarHBondContact O-N 3.04Å; H227-R241 PolarHBondContact CD2-NH2 3.33Å; H227-R241 VanDerWaalsContact CD2-NH2 3.32Å; H227-R241 PolarHBondContact CE1-NH1 3.39Å; H227-R241 PolarHBondContact CE1-NH2 2.59Å; H227-R241 VanDerWaalsContact CE1-NH2 3.25Å; H227-R241 VanDerWaalsContact CG-CZ 3.5Å; H227-R241 VanDerWaalsContact CG-NH1 3.3Å; H227-R241 PolarHBondContact ND1-NH1 3.32Å; H227-R241 VanDerWaalsContact NE2-CZ 3.35Å; H227-R241 PolarHBondContact NE2-NH2 3.36Å
228	L	88.7	Confident	89.8	Confident	15 Å²	15	42.3 Å²	42.3	8%	0.079	21%	0.211	C	C	.	.	G	3₁₀ helix	trans	-59.4	-31.8	-176.3	-176.7	58.3	0	0	0	112.8	E222 L226 E230 S231 I473 Y474 Y552	E222-L228 PolarHBondContact O-N 2.99Å; L226-L228 HydrophobicContact CB-CB 4.39Å; L226-L228 PolarHBondContact O-N 2.99Å; L228-E230 PolarHBondContact O-N 2.79Å; L228-E230 VanDerWaalsContact O-N 3.14Å; L228-S231 PolarHBondContact O-N 2.96Å; L228-I473 HydrophobicContact CD1-CG2 3.47Å; L228-I473 VanDerWaalsContact CD1-CG2 3.47Å; L228-I473 HydrophobicContact CD2-CG2 4.1Å; L228-I473 HydrophobicContact CG-CG2 4.38Å; L228-Y474 HydrophobicContact CD1-CD2 4.37Å; L228-Y474 HydrophobicContact CD1-CE2 3.62Å; L228-Y552 HydrophobicContact CD2-CE1 4.21Å
229	H	86.5	Confident	90.1	Very high	100 Å²	100	48.8 Å²	48.8	46%	0.463	24%	0.244	S	C	.	.	G	3₁₀ helix	trans	-60.9	-18.7	177.2	68.1	-77.5	0	0	0	114.2	R223 H227 S231	R223-H229 HydrophobicContact CG-CB 4.35Å; H227-H229 PolarHBondContact O-N 3.02Å; H227-H229 VanDerWaalsContact O-N 3.16Å; H229-S231 VanDerWaalsContact C-N 3.35Å
230	E	88.8	Confident	90.2	Very high	92 Å²	92	51.1 Å²	51.1	43%	0.43	26%	0.261	S	S	.	.	G	3₁₀ helix	trans	-83.4	-12.5	175.3	-61.3	177.9	-171.8	0	0	112.4	H227 L228 N470	H227-E230 HydrophobicContact CB-CG 4.46Å; H227-E230 IonicContact CE1-OE1 3.26Å; H227-E230 IonicContact CG-OE1 3.05Å; H227-E230 IonicContact ND1-OE1 3.91Å; H227-E230 PolarHBondContact ND1-OE1 3.39Å; H227-E230 IonicContact ND1-OE2 2.69Å; H227-E230 WeakPolarHBondContact O-CB 3.39Å; H227-E230 PolarHBondContact O-N 3.04Å; L228-E230 PolarHBondContact O-N 2.79Å; L228-E230 VanDerWaalsContact O-N 3.14Å; E230-N470 PolarHBondContact OE2-ND2 2.92Å
231	S	90.1	Very high	90.2	Very high	12 Å²	12	52.7 Å²	52.7	8%	0.084	27%	0.266	C	S	.	.			trans	-105.7	134.8	-179.3	176.8	0	0	0	0	111.6	L228 H229 G233 D236 G471	L228-S231 PolarHBondContact O-N 2.96Å; H229-S231 VanDerWaalsContact C-N 3.35Å; S231-G233 PolarHBondContact OG-N 2.59Å; S231-G233 PolarHBondContact OG-O 2.8Å; S231-G233 VanDerWaalsContact OG-O 3.13Å; S231-D236 WeakPolarHBondContact CB-O 3.46Å; S231-D236 PolarHBondContact OG-O 3.25Å; S231-G471 WeakPolarHBondContact OG-CA 3.41Å
232	K	87.1	Confident	90.2	Very high	183 Å²	183	60.9 Å²	60.9	80%	0.796	30%	0.297	S	S	*	.			trans	-89.6	-1.5	174.6	-63.4	178.8	-176.3	173.4	0	113.8
233	G	88.3	Confident	90.5	Very high	0 Å²	0	62.5 Å²	62.5	0%	0	31%	0.305	C	S	.	.	B	Isolated β-bridge	trans	146	-172.2	-176.9	0	0	0	0	0	113.4	S231 Q235 D236 Y474	S231-G233 PolarHBondContact OG-N 2.59Å; S231-G233 PolarHBondContact OG-O 2.8Å; S231-G233 VanDerWaalsContact OG-O 3.13Å; G233-Q235 PolarHBondContact O-N 2.92Å; G233-Q235 VanDerWaalsContact O-N 3.16Å; G233-D236 CarbonylContact O-C 3.39Å; G233-D236 PolarHBondContact O-N 3.1Å; G233-Y474 VanDerWaalsContact CA-CE2 3.49Å
234	I	89.7	Confident	90.7	Very high	13 Å²	13	58.7 Å²	58.7	7%	0.067	29%	0.291	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63.2	-21.6	-178.4	-165.7	169.2	0	0	0	113.8	D236 L237 V475 L478 Y555 F557 P558 W560 A561	I234-D236 VanDerWaalsContact C-N 3.26Å; I234-D236 PolarHBondContact O-N 3.31Å; I234-L237 HydrophobicContact CG1-CD2 4.48Å; I234-V475 HydrophobicContact CG1-CG2 4.38Å; I234-L478 HydrophobicContact CD1-CD1 4.41Å; I234-Y555 PolarHBondContact N-OH 3.41Å; I234-F557 HydrophobicContact CB-CE1 4.44Å; I234-F557 HydrophobicContact CD1-CD1 4.33Å; I234-F557 HydrophobicContact CD1-CE1 4.03Å; I234-F557 HydrophobicContact CG2-CD1 4.44Å; I234-P558 HydrophobicContact CG2-CG 4.02Å; I234-W560 HydrophobicContact CG1-CH2 4.37Å; I234-W560 HydrophobicContact CG2-CH2 3.83Å; I234-W560 HydrophobicContact CG2-CZ2 3.62Å; I234-A561 HydrophobicContact CD1-CB 4.38Å; I234-A561 HydrophobicContact CG2-CB 4.26Å
235	Q	89.4	Confident	91	Very high	118 Å²	118	59.6 Å²	59.6	55%	0.551	29%	0.294	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.8	-23.8	173.6	-65.9	86	-15.6	0	0	113.2	G233 Y555 W560	G233-Q235 PolarHBondContact O-N 2.92Å; G233-Q235 VanDerWaalsContact O-N 3.16Å; Q235-Y555 PolarHBondContact OE1-OH 3.31Å; Q235-W560 HydrophobicContact CG-CZ2 3.87Å
236	D	91.1	Very high	91.2	Very high	70 Å²	70	64.4 Å²	64.4	37%	0.374	32%	0.319	S	S	.	.	B	Isolated β-bridge	trans	-125.3	74.8	-170.7	-173.4	21.1	0	0	0	109.5	S231 G233 I234 G238	S231-D236 WeakPolarHBondContact CB-O 3.46Å; S231-D236 PolarHBondContact OG-O 3.25Å; G233-D236 CarbonylContact O-C 3.39Å; G233-D236 PolarHBondContact O-N 3.1Å; I234-D236 VanDerWaalsContact C-N 3.26Å; I234-D236 PolarHBondContact O-N 3.31Å; D236-G238 VanDerWaalsContact C-N 3.32Å; D236-G238 PolarHBondContact O-N 2.93Å
237	L	88.2	Confident	91.4	Very high	46 Å²	46	64.5 Å²	64.5	24%	0.241	32%	0.32	C	S	.	.			trans	-71.7	-26.9	-174.8	-64.5	178.9	0	0	0	112.6	I234 T469 N470 G471 V475	I234-L237 HydrophobicContact CG1-CD2 4.48Å; L237-T469 WeakPolarHBondContact O-CB 3.45Å; L237-T469 PolarHBondContact O-OG1 3.48Å; L237-N470 PolarHBondContact O-N 3.34Å; L237-N470 VanDerWaalsContact O-N 3.09Å; L237-G471 PolarHBondContact O-N 3.4Å; L237-V475 HydrophobicContact CD1-CG2 4.14Å; L237-V475 HydrophobicContact CD2-CG2 3.48Å; L237-V475 VanDerWaalsContact CD2-CG2 3.48Å; L237-V475 HydrophobicContact CG-CG2 4.49Å
238	G	91.1	Very high	91.7	Very high	40 Å²	40	62.9 Å²	62.9	41%	0.412	31%	0.313	S	S	.	.			trans	67.7	-160.2	-172.9	0	0	0	0	0	113	D236	D236-G238 VanDerWaalsContact C-N 3.32Å; D236-G238 PolarHBondContact O-N 2.93Å
239	L	91.4	Very high	92.1	Very high	137 Å²	137	65.4 Å²	65.4	72%	0.717	33%	0.328	S	S	*	.	P	Polyproline II helix	trans	-92.8	151.2	-178	-67	174.8	0	0	0	112	R241 T469 N470	L239-R241 PolarHBondContact O-N 3.17Å; L239-T469 WeakPolarHBondContact O-CA 3.37Å; L239-N470 PolarHBondContact O-N 2.76Å
240	P	92	Very high	92.6	Very high	60 Å²	60	63.2 Å²	63.2	39%	0.39	32%	0.322	S	S	.	.	B	Isolated β-bridge	trans	-60.5	133.2	170.4	-21.7	32.7	0	0	0	111.8	W242 I468 T469	P240-W242 PolarHBondContact O-N 2.98Å; P240-I468 HydrophobicContact CB-CG1 4.45Å; P240-T469 HydrophobicContact CG-CG2 4.04Å
241	R	92.7	Very high	92.9	Very high	46 Å²	46	58.9 Å²	58.9	17%	0.174	30%	0.302	C	S	.	.	P	Polyproline II helix	trans	-72	123.2	177.1	-64	-60.3	-56.1	-173.3	-6.8	110.4	H227 L239 E243 L244 T245 I468 N470	H227-R241 PolarHBondContact CD2-NH2 3.33Å; H227-R241 VanDerWaalsContact CD2-NH2 3.32Å; H227-R241 PolarHBondContact CE1-NH1 3.39Å; H227-R241 PolarHBondContact CE1-NH2 2.59Å; H227-R241 VanDerWaalsContact CE1-NH2 3.25Å; H227-R241 VanDerWaalsContact CG-CZ 3.5Å; H227-R241 VanDerWaalsContact CG-NH1 3.3Å; H227-R241 PolarHBondContact ND1-NH1 3.32Å; H227-R241 VanDerWaalsContact NE2-CZ 3.35Å; H227-R241 PolarHBondContact NE2-NH2 3.36Å; L239-R241 PolarHBondContact O-N 3.17Å; R241-E243 VanDerWaalsContact C-N 3.35Å; R241-E243 PolarHBondContact O-N 3.02Å; R241-L244 HydrophobicContact CB-CB 4.13Å; R241-L244 HydrophobicContact CB-CD1 4.14Å; R241-L244 HydrophobicContact CB-CG 4.12Å; R241-L244 HydrophobicContact CG-CD1 4.41Å; R241-L244 PolarHBondContact O-N 3.48Å; R241-T245 WeakPolarHBondContact O-CB 3.08Å; R241-T245 PolarHBondContact O-N 3.12Å; R241-T245 PolarHBondContact O-OG1 2.8Å; R241-I468 PolarHBondContact N-O 2.95Å; R241-N470 WeakPolarHBondContact CD-OD1 3.27Å
242	W	93.9	Very high	93.2	Very high	172 Å²	172	59.1 Å²	59.1	65%	0.652	30%	0.303	S	S	*	.	H	α-helix	trans	-64.6	-36.7	-174.8	73.3	-93.6	0	0	0	112.8	P240 T245 L246	P240-W242 PolarHBondContact O-N 2.98Å; W242-T245 WeakPolarHBondContact O-CB 3.38Å; W242-T245 PolarHBondContact O-N 2.65Å; W242-L246 PolarHBondContact O-N 3.16Å
243	E	94.6	Very high	93.6	Very high	68 Å²	68	56.5 Å²	56.5	32%	0.318	29%	0.292	S	S	.	.	H	α-helix	trans	-64.2	-46.7	178.1	-63.2	178.6	-172.5	0	0	111.7	H169 R241 T245 L246 C247	H169-E243 IonicContact CE1-OE2 2.8Å; H169-E243 PolarHBondContact CE1-OE2 2.96Å; H169-E243 VanDerWaalsContact CE1-OE2 3.29Å; R241-E243 VanDerWaalsContact C-N 3.35Å; R241-E243 PolarHBondContact O-N 3.02Å; E243-T245 VanDerWaalsContact C-N 3.33Å; E243-L246 PolarHBondContact O-N 3.16Å; E243-C247 PolarHBondContact O-N 3.12Å; E243-C247 VanDerWaalsContact O-N 3.07Å; E243-C247 PolarHBondContact O-SG 3.4Å
244	L	95.1	Very high	93.9	Very high	3 Å²	3	59.1 Å²	59.1	2%	0.016	31%	0.305	C	S	.	.	H	α-helix	trans	-69	-34	176	-62.9	-175.6	0	0	0	111.6	H169 V225 R241 C247 L248 I468	H169-L244 HydrophobicContact CB-CD2 3.94Å; V225-L244 HydrophobicContact CG1-CD1 4.38Å; V225-L244 HydrophobicContact CG1-CD2 3.99Å; R241-L244 HydrophobicContact CB-CB 4.13Å; R241-L244 HydrophobicContact CB-CD1 4.14Å; R241-L244 HydrophobicContact CB-CG 4.12Å; R241-L244 HydrophobicContact CG-CD1 4.41Å; R241-L244 PolarHBondContact O-N 3.48Å; L244-C247 PolarHBondContact O-N 3.37Å; L244-L248 VanDerWaalsContact O-CB 3.32Å; L244-L248 WeakPolarHBondContact O-CB 3.22Å; L244-L248 PolarHBondContact O-N 3.08Å; L244-I468 HydrophobicContact CB-CB 4.19Å; L244-I468 HydrophobicContact CB-CG2 4.29Å
245	T	96.3	Very high	94.2	Very high	32 Å²	32	58.5 Å²	58.5	20%	0.196	30%	0.302	C	S	.	.	H	α-helix	trans	-62	-44.8	174.5	-57.3	0	0	0	0	110.4	R241 W242 E243 L248 V249 F461 L465 I468	R241-T245 WeakPolarHBondContact O-CB 3.08Å; R241-T245 PolarHBondContact O-N 3.12Å; R241-T245 PolarHBondContact O-OG1 2.8Å; W242-T245 WeakPolarHBondContact O-CB 3.38Å; W242-T245 PolarHBondContact O-N 2.65Å; E243-T245 VanDerWaalsContact C-N 3.33Å; T245-L248 PolarHBondContact O-N 3.29Å; T245-V249 WeakPolarHBondContact O-CG2 3.41Å; T245-V249 PolarHBondContact O-N 3.29Å; T245-F461 HydrophobicContact CG2-CE2 4.47Å; T245-F461 HydrophobicContact CG2-CZ 4.27Å; T245-L465 HydrophobicContact CG2-CD2 3.9Å; T245-I468 HydrophobicContact CG2-CD1 4.43Å; T245-I468 WeakPolarHBondContact OG1-CD1 3.38Å
246	L	96.6	Very high	94.5	Very high	104 Å²	104	55.1 Å²	55.1	55%	0.545	28%	0.284	S	S	.	.	H	α-helix	trans	-62.5	-44.4	176.1	-175.3	68.5	0	0	0	111.4	W242 E243 L248 V249 V250	W242-L246 PolarHBondContact O-N 3.16Å; E243-L246 PolarHBondContact O-N 3.16Å; L246-L248 VanDerWaalsContact C-N 3.31Å; L246-L248 PolarHBondContact O-N 3.02Å; L246-V249 WeakPolarHBondContact O-CB 3.24Å; L246-V249 PolarHBondContact O-N 2.8Å; L246-V250 WeakPolarHBondContact O-CG2 3.43Å; L246-V250 PolarHBondContact O-N 2.98Å
247	C	97.1	Very high	94.7	Very high	9 Å²	9	55.3 Å²	55.3	6%	0.061	28%	0.282	C	S	.	.	H	α-helix	trans	-60.3	-42.5	175.6	-64.8	0	0	0	0	111.4	A165 L168 E243 L244 V250 V251	A165-C247 HydrophobicContact CB-CB 4.14Å; A165-C247 WeakPolarHBondContact O-CB 3.23Å; L168-C247 HydrophobicContact CB-CB 4.44Å; L168-C247 HydrophobicContact CD2-CB 4.15Å; L168-C247 HydrophobicContact CG-CB 4.41Å; E243-C247 PolarHBondContact O-N 3.12Å; E243-C247 VanDerWaalsContact O-N 3.07Å; E243-C247 PolarHBondContact O-SG 3.4Å; L244-C247 PolarHBondContact O-N 3.37Å; C247-V250 PolarHBondContact O-N 3.01Å; C247-V251 WeakPolarHBondContact O-CG2 3.08Å; C247-V251 PolarHBondContact O-N 3.14Å
248	L	96.5	Very high	94.9	Very high	0 Å²	0	53.4 Å²	53.4	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-64.5	-39.7	177.2	-174.5	67.9	0	0	0	112	N161 A165 L244 T245 L246 V250 V251 V252 F461 A464 L465 I468	N161-L248 HydrophobicContact CB-CD1 4.03Å; A165-L248 HydrophobicContact CB-CB 4.03Å; A165-L248 HydrophobicContact CB-CD1 4.15Å; L244-L248 VanDerWaalsContact O-CB 3.32Å; L244-L248 WeakPolarHBondContact O-CB 3.22Å; L244-L248 PolarHBondContact O-N 3.08Å; T245-L248 PolarHBondContact O-N 3.29Å; L246-L248 VanDerWaalsContact C-N 3.31Å; L246-L248 PolarHBondContact O-N 3.02Å; L248-V250 VanDerWaalsContact C-N 3.3Å; L248-V250 PolarHBondContact O-N 3.34Å; L248-V251 PolarHBondContact O-N 3.09Å; L248-V252 HydrophobicContact CD1-CG2 4.49Å; L248-V252 HydrophobicContact CG-CG2 4.49Å; L248-V252 WeakPolarHBondContact O-CB 3.35Å; L248-V252 VanDerWaalsContact O-CG2 3.25Å; L248-V252 WeakPolarHBondContact O-CG2 3.48Å; L248-V252 PolarHBondContact O-N 3.04Å; L248-F461 HydrophobicContact CB-CE2 4.45Å; L248-F461 HydrophobicContact CD2-CD2 3.72Å; L248-F461 HydrophobicContact CD2-CE2 3.92Å; L248-F461 HydrophobicContact CG-CD2 3.84Å; L248-F461 HydrophobicContact CG-CE2 4.14Å; L248-A464 HydrophobicContact CD1-CB 4.28Å; L248-A464 HydrophobicContact CD2-CB 3.73Å; L248-L465 HydrophobicContact CD2-CD2 4.39Å; L248-I468 HydrophobicContact CD2-CD1 4.06Å
249	V	97.1	Very high	95.1	Very high	68 Å²	68	51.5 Å²	51.5	41%	0.412	25%	0.253	S	S	.	.	H	α-helix	trans	-58.3	-44.2	172.7	169.4	0	0	0	0	110.6	T245 L246 V252 F253 F461	T245-V249 WeakPolarHBondContact O-CG2 3.41Å; T245-V249 PolarHBondContact O-N 3.29Å; L246-V249 WeakPolarHBondContact O-CB 3.24Å; L246-V249 PolarHBondContact O-N 2.8Å; V249-V252 PolarHBondContact O-N 2.85Å; V249-F253 VanDerWaalsContact O-CB 3.28Å; V249-F253 WeakPolarHBondContact O-CB 3.41Å; V249-F253 PolarHBondContact O-N 2.82Å; V249-F461 HydrophobicContact CG2-CD2 4.42Å; V249-F461 HydrophobicContact CG2-CE2 3.51Å; V249-F461 HydrophobicContact CG2-CZ 3.7Å
250	V	97.1	Very high	95	Very high	54 Å²	54	48.7 Å²	48.7	33%	0.327	23%	0.233	S	C	.	.	H	α-helix	trans	-64.1	-43.9	177.6	174.6	0	0	0	0	111.4	L168 L246 C247 L248 F253 I254	L168-V250 HydrophobicContact CD2-CB 3.73Å; L168-V250 HydrophobicContact CD2-CG1 3.61Å; L246-V250 WeakPolarHBondContact O-CG2 3.43Å; L246-V250 PolarHBondContact O-N 2.98Å; C247-V250 PolarHBondContact O-N 3.01Å; L248-V250 VanDerWaalsContact C-N 3.3Å; L248-V250 PolarHBondContact O-N 3.34Å; V250-F253 WeakPolarHBondContact O-CB 3.47Å; V250-F253 PolarHBondContact O-N 2.89Å; V250-I254 HydrophobicContact CG1-CD1 3.94Å; V250-I254 WeakPolarHBondContact O-CG1 3.44Å; V250-I254 PolarHBondContact O-N 3.42Å
251	V	96.2	Very high	94.9	Very high	1 Å²	1	51.3 Å²	51.3	1%	0.006	24%	0.238	C	C	.	.	H	α-helix	trans	-58.9	-50	176.2	169.6	0	0	0	0	110.9	I164 A165 L168 C247 L248 F253 I254 L255	I164-V251 HydrophobicContact CB-CG1 4.01Å; I164-V251 HydrophobicContact CB-CG2 4.14Å; I164-V251 HydrophobicContact CD1-CG1 4.32Å; I164-V251 HydrophobicContact CG2-CB 4.47Å; I164-V251 HydrophobicContact CG2-CG1 3.87Å; I164-V251 HydrophobicContact CG2-CG2 3.68Å; A165-V251 HydrophobicContact CB-CG2 4.4Å; L168-V251 HydrophobicContact CD2-CG2 4.13Å; C247-V251 WeakPolarHBondContact O-CG2 3.08Å; C247-V251 PolarHBondContact O-N 3.14Å; L248-V251 PolarHBondContact O-N 3.09Å; V251-F253 VanDerWaalsContact C-N 3.28Å; V251-F253 PolarHBondContact O-N 3.03Å; V251-I254 PolarHBondContact O-N 3.21Å; V251-I254 VanDerWaalsContact O-N 3.14Å; V251-L255 HydrophobicContact CG1-CD1 4.01Å; V251-L255 HydrophobicContact CG1-CG 4.43Å; V251-L255 WeakPolarHBondContact O-CG 3.45Å; V251-L255 PolarHBondContact O-N 3.11Å
252	V	95.3	Very high	94.7	Very high	18 Å²	18	49.1 Å²	49.1	11%	0.109	23%	0.23	C	C	.	.	H	α-helix	trans	-63.3	-36.9	-179.9	172.1	0	0	0	0	111.3	L248 V249 L255 Y256 A457 F461	L248-V252 HydrophobicContact CD1-CG2 4.49Å; L248-V252 HydrophobicContact CG-CG2 4.49Å; L248-V252 WeakPolarHBondContact O-CB 3.35Å; L248-V252 VanDerWaalsContact O-CG2 3.25Å; L248-V252 WeakPolarHBondContact O-CG2 3.48Å; L248-V252 PolarHBondContact O-N 3.04Å; V249-V252 PolarHBondContact O-N 2.85Å; V252-L255 PolarHBondContact O-N 3.39Å; V252-Y256 WeakPolarHBondContact O-CB 3.45Å; V252-Y256 PolarHBondContact O-N 3.37Å; V252-A457 HydrophobicContact CG1-CB 3.96Å; V252-A457 WeakPolarHBondContact CG1-O 3.13Å; V252-F461 HydrophobicContact CG1-CB 4.3Å; V252-F461 HydrophobicContact CG2-CB 4Å; V252-F461 HydrophobicContact CG2-CD2 4.24Å
253	F	95.9	Very high	94.4	Very high	128 Å²	128	41 Å²	41	56%	0.561	20%	0.2	S	C	*	.	H	α-helix	trans	-61.3	-48.7	172.8	-176.4	-86.1	0	0	0	111.3	V249 V250 V251 L255 Y256 F257	V249-F253 VanDerWaalsContact O-CB 3.28Å; V249-F253 WeakPolarHBondContact O-CB 3.41Å; V249-F253 PolarHBondContact O-N 2.82Å; V250-F253 WeakPolarHBondContact O-CB 3.47Å; V250-F253 PolarHBondContact O-N 2.89Å; V251-F253 VanDerWaalsContact C-N 3.28Å; V251-F253 PolarHBondContact O-N 3.03Å; F253-L255 VanDerWaalsContact C-N 3.33Å; F253-L255 PolarHBondContact O-N 3.37Å; F253-Y256 PolarHBondContact O-N 3.25Å; F253-F257 AromaticContact CD1-CD2 3.73Å; F253-F257 HydrophobicContact CD1-CD2 3.73Å; F253-F257 HydrophobicContact CD1-CE2 4.02Å; F253-F257 HydrophobicContact CD2-CD2 4.14Å; F253-F257 AromaticContact CD2-CE2 3.69Å; F253-F257 HydrophobicContact CD2-CE2 3.69Å; F253-F257 AromaticContact CE1-CD2 3.5Å; F253-F257 HydrophobicContact CE1-CD2 3.5Å; F253-F257 AromaticContact CE1-CE2 3.57Å; F253-F257 HydrophobicContact CE1-CE2 3.57Å; F253-F257 AromaticContact CE2-CD2 3.98Å; F253-F257 HydrophobicContact CE2-CD2 3.98Å; F253-F257 AromaticContact CE2-CE2 3.23Å; F253-F257 HydrophobicContact CE2-CE2 3.23Å; F253-F257 HydrophobicContact CE2-CZ 4.09Å; F253-F257 HydrophobicContact CG-CD2 4.04Å; F253-F257 HydrophobicContact CG-CE2 4.07Å; F253-F257 AromaticContact CZ-CD2 3.64Å; F253-F257 HydrophobicContact CZ-CD2 3.64Å; F253-F257 AromaticContact CZ-CE2 3.15Å; F253-F257 HydrophobicContact CZ-CE2 3.15Å; F253-F257 AromaticContact CZ-CZ 3.92Å; F253-F257 HydrophobicContact CZ-CZ 3.92Å; F253-F257 VanDerWaalsContact O-CD2 3.3Å; F253-F257 WeakPolarHBondContact O-CD2 3.19Å; F253-F257 PolarHBondContact O-N 3.37Å
254	I	95.3	Very high	94.2	Very high	54 Å²	54	43.1 Å²	43.1	28%	0.277	21%	0.207	S	C	.	.	H	α-helix	trans	-59	-45.2	176.8	-67.3	164.8	0	0	0	110.7	V250 V251 F257 S258 I424	V250-I254 HydrophobicContact CG1-CD1 3.94Å; V250-I254 WeakPolarHBondContact O-CG1 3.44Å; V250-I254 PolarHBondContact O-N 3.42Å; V251-I254 PolarHBondContact O-N 3.21Å; V251-I254 VanDerWaalsContact O-N 3.14Å; I254-F257 PolarHBondContact O-N 3.43Å; I254-S258 VanDerWaalsContact O-CB 3.3Å; I254-S258 WeakPolarHBondContact O-CB 3.32Å; I254-S258 PolarHBondContact O-N 3.13Å; I254-S258 PolarHBondContact O-OG 2.89Å; I254-I424 HydrophobicContact CG2-CD1 4Å; I254-I424 HydrophobicContact CG2-CG2 4.49Å
255	L	95.1	Very high	94	Very high	1 Å²	1	43.9 Å²	43.9	1%	0.005	21%	0.213	C	C	.	.	H	α-helix	trans	-61.9	-45.3	178.1	-68.5	173.6	0	0	0	112	N161 V251 V252 F253 S258 L259 I424 S427 M428	N161-L255 WeakPolarHBondContact OD1-CD1 3.41Å; V251-L255 HydrophobicContact CG1-CD1 4.01Å; V251-L255 HydrophobicContact CG1-CG 4.43Å; V251-L255 WeakPolarHBondContact O-CG 3.45Å; V251-L255 PolarHBondContact O-N 3.11Å; V252-L255 PolarHBondContact O-N 3.39Å; F253-L255 VanDerWaalsContact C-N 3.33Å; F253-L255 PolarHBondContact O-N 3.37Å; L255-S258 PolarHBondContact O-N 3.38Å; L255-L259 WeakPolarHBondContact O-CG 3.29Å; L255-L259 PolarHBondContact O-N 2.71Å; L255-I424 HydrophobicContact CD2-CG2 4.34Å; L255-S427 WeakPolarHBondContact CD1-OG 3.41Å; L255-M428 HydrophobicContact CD2-CG 3.76Å
256	Y	95.5	Very high	93.7	Very high	46 Å²	46	42.4 Å²	42.4	18%	0.18	20%	0.204	C	C	.	.	H	α-helix	trans	-58.5	-51.6	177.8	171.5	-105.4	0	0	0	111.8	V252 F253 S258 L259 W260 T453 F454	V252-Y256 WeakPolarHBondContact O-CB 3.45Å; V252-Y256 PolarHBondContact O-N 3.37Å; F253-Y256 PolarHBondContact O-N 3.25Å; Y256-S258 VanDerWaalsContact C-N 3.27Å; Y256-S258 PolarHBondContact O-N 3.24Å; Y256-L259 PolarHBondContact O-N 3.2Å; Y256-W260 HydrophobicContact CE2-CB 4.48Å; Y256-W260 WeakPolarHBondContact O-CB 3.07Å; Y256-W260 PolarHBondContact O-N 3.38Å; Y256-T453 HydrophobicContact CD2-CG2 4Å; Y256-T453 HydrophobicContact CE2-CG2 4.38Å; Y256-F454 HydrophobicContact CD2-CB 4.03Å; Y256-F454 HydrophobicContact CD2-CD2 4.33Å; Y256-F454 HydrophobicContact CE2-CB 3.58Å; Y256-F454 HydrophobicContact CE2-CD2 4.26Å; Y256-F454 HydrophobicContact CE2-CG 4.42Å
257	F	95	Very high	93.4	Very high	75 Å²	75	37.5 Å²	37.5	33%	0.329	18%	0.179	S	C	.	.	H	α-helix	trans	-68.8	-25.3	179.2	-79	-78.1	0	0	0	113.2	F253 I254 W260 S265	F253-F257 AromaticContact CD1-CD2 3.73Å; F253-F257 HydrophobicContact CD1-CD2 3.73Å; F253-F257 HydrophobicContact CD1-CE2 4.02Å; F253-F257 HydrophobicContact CD2-CD2 4.14Å; F253-F257 AromaticContact CD2-CE2 3.69Å; F253-F257 HydrophobicContact CD2-CE2 3.69Å; F253-F257 AromaticContact CE1-CD2 3.5Å; F253-F257 HydrophobicContact CE1-CD2 3.5Å; F253-F257 AromaticContact CE1-CE2 3.57Å; F253-F257 HydrophobicContact CE1-CE2 3.57Å; F253-F257 AromaticContact CE2-CD2 3.98Å; F253-F257 HydrophobicContact CE2-CD2 3.98Å; F253-F257 AromaticContact CE2-CE2 3.23Å; F253-F257 HydrophobicContact CE2-CE2 3.23Å; F253-F257 HydrophobicContact CE2-CZ 4.09Å; F253-F257 HydrophobicContact CG-CD2 4.04Å; F253-F257 HydrophobicContact CG-CE2 4.07Å; F253-F257 AromaticContact CZ-CD2 3.64Å; F253-F257 HydrophobicContact CZ-CD2 3.64Å; F253-F257 AromaticContact CZ-CE2 3.15Å; F253-F257 HydrophobicContact CZ-CE2 3.15Å; F253-F257 AromaticContact CZ-CZ 3.92Å; F253-F257 HydrophobicContact CZ-CZ 3.92Å; F253-F257 VanDerWaalsContact O-CD2 3.3Å; F253-F257 WeakPolarHBondContact O-CD2 3.19Å; F253-F257 PolarHBondContact O-N 3.37Å; I254-F257 PolarHBondContact O-N 3.43Å; F257-W260 HydrophobicContact CD1-CD2 4.04Å; F257-W260 AromaticContact CD1-CE3 3.85Å; F257-W260 HydrophobicContact CD1-CE3 3.85Å; F257-W260 HydrophobicContact CD1-CH2 4.05Å; F257-W260 HydrophobicContact CD1-CZ2 4.21Å; F257-W260 AromaticContact CD1-CZ3 3.86Å; F257-W260 HydrophobicContact CD1-CZ3 3.86Å; F257-W260 AromaticContact CE1-CE3 3.91Å; F257-W260 HydrophobicContact CE1-CE3 3.91Å; F257-W260 HydrophobicContact CE1-CH2 4.05Å; F257-W260 AromaticContact CE1-CZ3 3.63Å; F257-W260 HydrophobicContact CE1-CZ3 3.63Å; F257-W260 PolarHBondContact O-NE1 3.48Å; F257-W260 VanDerWaalsContact O-NE1 3.12Å; F257-S265 PolarHBondContact O-OG 3.07Å
258	S	94.1	Very high	93.1	Very high	6 Å²	6	44.6 Å²	44.6	4%	0.042	21%	0.209	C	C	.	.	H	α-helix	trans	-70.5	-34.8	174	-59.4	0	0	0	0	111.6	I254 L255 Y256 S265 S266 M428	I254-S258 VanDerWaalsContact O-CB 3.3Å; I254-S258 WeakPolarHBondContact O-CB 3.32Å; I254-S258 PolarHBondContact O-N 3.13Å; I254-S258 PolarHBondContact O-OG 2.89Å; L255-S258 PolarHBondContact O-N 3.38Å; Y256-S258 VanDerWaalsContact C-N 3.27Å; Y256-S258 PolarHBondContact O-N 3.24Å; S258-S265 CarbonylContact O-C 3.45Å; S258-S265 VanDerWaalsContact O-CB 3.23Å; S258-S265 WeakPolarHBondContact O-CB 3.26Å; S258-S265 PolarHBondContact O-OG 3.14Å; S258-S266 PolarHBondContact O-N 2.85Å; S258-S266 VanDerWaalsContact O-N 3.09Å; S258-M428 VanDerWaalsContact CB-SD 3.52Å
259	L	93.6	Very high	93	Very high	0 Å²	0	46.6 Å²	46.6	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-102.1	-12.9	-174.8	-62.3	176.8	0	0	0	115.4	L255 Y256 K261 G262 M428 M431 E432 I435 T453	L255-L259 WeakPolarHBondContact O-CG 3.29Å; L255-L259 PolarHBondContact O-N 2.71Å; Y256-L259 PolarHBondContact O-N 3.2Å; L259-K261 PolarHBondContact O-N 2.95Å; L259-G262 WeakPolarHBondContact O-CA 3.08Å; L259-G262 PolarHBondContact O-N 2.96Å; L259-M428 HydrophobicContact CD2-CB 4.18Å; L259-M428 HydrophobicContact CD2-CG 4.34Å; L259-M428 HydrophobicContact CG-CG 4.44Å; L259-M431 HydrophobicContact CD1-CB 3.69Å; L259-M431 HydrophobicContact CD1-CG 3.62Å; L259-M431 HydrophobicContact CD1-SD 3.7Å; L259-E432 HydrophobicContact CD2-CB 4.23Å; L259-I435 HydrophobicContact CD1-CD1 4.28Å; L259-T453 HydrophobicContact CB-CG2 3.97Å
260	W	90.9	Very high	92.8	Very high	77 Å²	77	43.5 Å²	43.5	29%	0.292	20%	0.202	S	C	.	.	T	Hydrogen-bonded Turn	trans	-57.1	-24.5	-172.5	73.4	-29.4	0	0	0	116.4	Y256 F257	Y256-W260 HydrophobicContact CE2-CB 4.48Å; Y256-W260 WeakPolarHBondContact O-CB 3.07Å; Y256-W260 PolarHBondContact O-N 3.38Å; F257-W260 HydrophobicContact CD1-CD2 4.04Å; F257-W260 AromaticContact CD1-CE3 3.85Å; F257-W260 HydrophobicContact CD1-CE3 3.85Å; F257-W260 HydrophobicContact CD1-CH2 4.05Å; F257-W260 HydrophobicContact CD1-CZ2 4.21Å; F257-W260 AromaticContact CD1-CZ3 3.86Å; F257-W260 HydrophobicContact CD1-CZ3 3.86Å; F257-W260 AromaticContact CE1-CE3 3.91Å; F257-W260 HydrophobicContact CE1-CE3 3.91Å; F257-W260 HydrophobicContact CE1-CH2 4.05Å; F257-W260 AromaticContact CE1-CZ3 3.63Å; F257-W260 HydrophobicContact CE1-CZ3 3.63Å; F257-W260 PolarHBondContact O-NE1 3.48Å; F257-W260 VanDerWaalsContact O-NE1 3.12Å
261	K	88.9	Confident	92.7	Very high	116 Å²	116	44.9 Å²	44.9	50%	0.504	20%	0.202	S	C	.	.	T	Hydrogen-bonded Turn	trans	-112.8	21.7	175.3	-60.8	171.1	-179.4	176	0	111.4	L259	L259-K261 PolarHBondContact O-N 2.95Å
262	G	88.6	Confident	92.5	Very high	0 Å²	0	49.8 Å²	49.8	0%	0	23%	0.227	C	C	.	.	T	Hydrogen-bonded Turn	trans	59.2	-147	-176.5	0	0	0	0	0	113.2	L259 K264 S265 S266	L259-G262 WeakPolarHBondContact O-CA 3.08Å; L259-G262 PolarHBondContact O-N 2.96Å; G262-K264 PolarHBondContact O-N 3.12Å; G262-S265 PolarHBondContact O-N 3.41Å; G262-S266 PolarHBondContact O-N 3.45Å; G262-S266 VanDerWaalsContact O-N 3.14Å
263	V	88.8	Confident	92.4	Very high	2 Å²	2	49.4 Å²	49.4	1%	0.012	23%	0.225	C	C	.	.	H	α-helix	trans	-56.7	-22.5	-176.4	-65.3	0	0	0	0	114.8	W67 G267 Y339	W67-V263 HydrophobicContact CD2-CB 4.12Å; W67-V263 HydrophobicContact CD2-CG1 4.47Å; W67-V263 HydrophobicContact CE3-CB 3.86Å; W67-V263 HydrophobicContact CE3-CG1 4.45Å; W67-V263 HydrophobicContact CH2-CB 3.86Å; W67-V263 HydrophobicContact CH2-CG1 3.64Å; W67-V263 HydrophobicContact CZ2-CB 4.11Å; W67-V263 HydrophobicContact CZ2-CG1 3.64Å; W67-V263 HydrophobicContact CZ3-CB 3.72Å; W67-V263 HydrophobicContact CZ3-CG1 4.06Å; V263-G267 WeakPolarHBondContact O-CA 3.48Å; V263-G267 PolarHBondContact O-N 2.91Å; V263-Y339 HydrophobicContact CB-CD2 4.49Å; V263-Y339 HydrophobicContact CG1-CD1 4.5Å; V263-Y339 HydrophobicContact CG1-CD2 3.32Å; V263-Y339 HydrophobicContact CG1-CE2 3.62Å; V263-Y339 HydrophobicContact CG1-CG 3.81Å; V263-Y339 HydrophobicContact CG2-CD1 4.24Å; V263-Y339 HydrophobicContact CG2-CD2 4.45Å; V263-Y339 HydrophobicContact CG2-CG 4.11Å
264	K	88.6	Confident	92.3	Very high	111 Å²	111	43.5 Å²	43.5	48%	0.483	20%	0.2	S	C	.	.	H	α-helix	trans	-72.1	-27.8	177	-68.3	179.6	-178.5	155.3	0	113.9	E65 G262	E65-K264 IonicContact OE1-NZ 2.89Å; E65-K264 PolarHBondContact OE1-NZ 3.37Å; G262-K264 PolarHBondContact O-N 3.12Å
265	S	91.3	Very high	92.2	Very high	19 Å²	19	43.5 Å²	43.5	13%	0.133	20%	0.202	C	C	.	.	H	α-helix	trans	-90.4	-48.5	174.7	-172.5	0	0	0	0	109.9	F257 S258 G262 G267 K268 V269	F257-S265 PolarHBondContact O-OG 3.07Å; S258-S265 CarbonylContact O-C 3.45Å; S258-S265 VanDerWaalsContact O-CB 3.23Å; S258-S265 WeakPolarHBondContact O-CB 3.26Å; S258-S265 PolarHBondContact O-OG 3.14Å; G262-S265 PolarHBondContact O-N 3.41Å; S265-G267 VanDerWaalsContact C-N 3.32Å; S265-G267 PolarHBondContact O-N 3.42Å; S265-K268 PolarHBondContact O-N 3.19Å; S265-V269 PolarHBondContact O-N 3.27Å
266	S	90.9	Very high	92.1	Very high	2 Å²	2	47 Å²	47	1%	0.014	22%	0.219	C	C	.	.	H	α-helix	trans	-53.3	-49	177.1	176.7	0	0	0	0	111.6	S258 G262 K268 V269 V270 M428	S258-S266 PolarHBondContact O-N 2.85Å; S258-S266 VanDerWaalsContact O-N 3.09Å; G262-S266 PolarHBondContact O-N 3.45Å; G262-S266 VanDerWaalsContact O-N 3.14Å; S266-K268 PolarHBondContact O-N 3.31Å; S266-V269 PolarHBondContact O-N 3.31Å; S266-V270 WeakPolarHBondContact O-CG1 3.42Å; S266-V270 PolarHBondContact O-N 3.26Å; S266-V270 VanDerWaalsContact O-N 3.12Å; S266-M428 WeakPolarHBondContact OG-CE 3.26Å
267	G	89.8	Confident	92	Very high	1 Å²	1	45 Å²	45	1%	0.01	21%	0.212	C	C	.	.	H	α-helix	trans	-60.1	-15.2	179	0	0	0	0	0	115.6	V263 S265 V270 Y271	V263-G267 WeakPolarHBondContact O-CA 3.48Å; V263-G267 PolarHBondContact O-N 2.91Å; S265-G267 VanDerWaalsContact C-N 3.32Å; S265-G267 PolarHBondContact O-N 3.42Å; G267-V270 WeakPolarHBondContact O-CG2 3.41Å; G267-Y271 VanDerWaalsContact O-CD2 3.23Å; G267-Y271 WeakPolarHBondContact O-CD2 3.38Å; G267-Y271 WeakPolarHBondContact O-CE2 3.37Å
268	K	91.8	Very high	91.9	Very high	158 Å²	158	45 Å²	45	69%	0.687	21%	0.21	S	C	*	.	H	α-helix	trans	-92.2	-37.6	173.3	-65.2	-178.4	-178.5	-176.5	0	112.5	S265 S266 V270 Y271	S265-K268 PolarHBondContact O-N 3.19Å; S266-K268 PolarHBondContact O-N 3.31Å; K268-V270 VanDerWaalsContact C-N 3.34Å; K268-Y271 PolarHBondContact O-N 3.27Å
269	V	93.2	Very high	91.8	Very high	41 Å²	41	49.3 Å²	49.3	25%	0.248	23%	0.232	C	C	.	.	H	α-helix	trans	-65.1	-41.6	179.6	178.4	0	0	0	0	110.2	S265 S266 Y271 I272 T273 M428	S265-V269 PolarHBondContact O-N 3.27Å; S266-V269 PolarHBondContact O-N 3.31Å; V269-Y271 PolarHBondContact O-N 3.01Å; V269-I272 PolarHBondContact O-N 2.83Å; V269-T273 HydrophobicContact CG1-CG2 4Å; V269-T273 PolarHBondContact O-N 3.39Å; V269-T273 PolarHBondContact O-OG1 2.85Å; V269-T273 VanDerWaalsContact O-OG1 3.1Å; V269-M428 HydrophobicContact CB-CE 4.26Å; V269-M428 HydrophobicContact CG1-CE 4.39Å; V269-M428 HydrophobicContact CG1-SD 4.13Å
270	V	94.1	Very high	91.8	Very high	3 Å²	3	49.8 Å²	49.8	2%	0.018	24%	0.235	C	C	.	.	H	α-helix	trans	-57.6	-20	-179.7	-61.9	0	0	0	0	115.1	L75 S266 G267 K268 I272 T273 A274 M428	L75-V270 HydrophobicContact CB-CB 4.44Å; L75-V270 HydrophobicContact CB-CG2 4.08Å; S266-V270 WeakPolarHBondContact O-CG1 3.42Å; S266-V270 PolarHBondContact O-N 3.26Å; S266-V270 VanDerWaalsContact O-N 3.12Å; G267-V270 WeakPolarHBondContact O-CG2 3.41Å; K268-V270 VanDerWaalsContact C-N 3.34Å; V270-I272 PolarHBondContact O-N 3.22Å; V270-T273 WeakPolarHBondContact CA-OG1 3.46Å; V270-A274 WeakPolarHBondContact O-CB 3.28Å; V270-A274 PolarHBondContact O-N 3.21Å; V270-M428 HydrophobicContact CG1-CE 4.15Å
271	Y	93.3	Very high	91.8	Very high	83 Å²	83	46.2 Å²	46.2	33%	0.325	22%	0.221	S	C	.	.	H	α-helix	trans	-64.2	-32.7	174.4	-82.5	-98.1	0	0	0	112.4	I71 D72 L75 G267 K268 V269 T275	I71-Y271 WeakPolarHBondContact CG2-OH 3.5Å; D72-Y271 WeakPolarHBondContact OD1-CE2 3.43Å; D72-Y271 VanDerWaalsContact OD1-CZ 3.31Å; D72-Y271 PolarHBondContact OD1-OH 3.46Å; L75-Y271 HydrophobicContact CD1-CD1 3.95Å; L75-Y271 HydrophobicContact CD1-CD2 4.45Å; L75-Y271 HydrophobicContact CD1-CE1 4.08Å; L75-Y271 HydrophobicContact CD1-CG 4.17Å; G267-Y271 VanDerWaalsContact O-CD2 3.23Å; G267-Y271 WeakPolarHBondContact O-CD2 3.38Å; G267-Y271 WeakPolarHBondContact O-CE2 3.37Å; K268-Y271 PolarHBondContact O-N 3.27Å; V269-Y271 PolarHBondContact O-N 3.01Å; Y271-T275 WeakPolarHBondContact O-CB 3.24Å; Y271-T275 WeakPolarHBondContact O-CG2 3.05Å; Y271-T275 PolarHBondContact O-OG1 3.31Å
272	I	93.1	Very high	91.9	Very high	105 Å²	105	46.2 Å²	46.2	54%	0.538	22%	0.222	S	C	.	.	H	α-helix	trans	-89.5	-51.7	178.1	-61.9	175.6	0	0	0	108.9	V269 V270 A274 T275 M276	V269-I272 PolarHBondContact O-N 2.83Å; V270-I272 PolarHBondContact O-N 3.22Å; I272-A274 PolarHBondContact O-N 2.76Å; I272-T275 PolarHBondContact O-N 2.92Å; I272-M276 HydrophobicContact CG2-CE 4.4Å; I272-M276 HydrophobicContact CG2-CG 3.96Å; I272-M276 WeakPolarHBondContact O-CB 3.28Å; I272-M276 WeakPolarHBondContact O-CG 3.45Å; I272-M276 PolarHBondContact O-N 3.05Å
273	T	93.6	Very high	92.1	Very high	10 Å²	10	48.9 Å²	48.9	6%	0.061	24%	0.238	C	C	.	.	H	α-helix	trans	-67	-35.6	-171.9	42.8	0	0	0	0	112.5	V269 V270 P277 T421 I424 D425	V269-T273 HydrophobicContact CG1-CG2 4Å; V269-T273 PolarHBondContact O-N 3.39Å; V269-T273 PolarHBondContact O-OG1 2.85Å; V269-T273 VanDerWaalsContact O-OG1 3.1Å; V270-T273 WeakPolarHBondContact CA-OG1 3.46Å; T273-P277 WeakPolarHBondContact O-CD 3.44Å; T273-P277 WeakPolarHBondContact O-CG 3.28Å; T273-T421 HydrophobicContact CG2-CG2 4.12Å; T273-I424 HydrophobicContact CG2-CG2 4.2Å; T273-D425 WeakPolarHBondContact CB-OD1 3.33Å; T273-D425 VanDerWaalsContact CB-OD2 3.25Å; T273-D425 WeakPolarHBondContact CB-OD2 3.25Å; T273-D425 PolarHBondContact OG1-OD1 3.16Å; T273-D425 PolarHBondContact OG1-OD2 3.1Å; T273-D425 VanDerWaalsContact OG1-OD2 3.12Å
274	A	93.4	Very high	92.1	Very high	4 Å²	4	49.6 Å²	49.6	3%	0.033	24%	0.241	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.6	-25	179.7	0	0	0	0	0	112.9	L75 V270 I272 Y278 D425	L75-A274 HydrophobicContact CB-CB 4.46Å; V270-A274 WeakPolarHBondContact O-CB 3.28Å; V270-A274 PolarHBondContact O-N 3.21Å; I272-A274 PolarHBondContact O-N 2.76Å; A274-Y278 WeakPolarHBondContact O-CD2 3.46Å; A274-Y278 WeakPolarHBondContact O-CE2 3.33Å; A274-D425 VanDerWaalsContact CA-OD2 3.22Å; A274-D425 WeakPolarHBondContact CA-OD2 3.26Å; A274-D425 WeakPolarHBondContact CB-OD2 3.29Å; A274-D425 PolarHBondContact N-OD2 3.49Å
275	T	93.4	Very high	92.2	Very high	54 Å²	54	45.4 Å²	45.4	33%	0.331	22%	0.224	S	C	.	.	T	Hydrogen-bonded Turn	trans	-92.9	-34.6	-175.1	65.8	0	0	0	0	113.5	L75 Y271 I272 Y278 I279	L75-T275 HydrophobicContact CD2-CG2 4.44Å; Y271-T275 WeakPolarHBondContact O-CB 3.24Å; Y271-T275 WeakPolarHBondContact O-CG2 3.05Å; Y271-T275 PolarHBondContact O-OG1 3.31Å; I272-T275 PolarHBondContact O-N 2.92Å; T275-Y278 PolarHBondContact O-N 3.46Å; T275-I279 PolarHBondContact O-N 3.01Å
276	M	92.4	Very high	92.3	Very high	74 Å²	74	48.7 Å²	48.7	37%	0.365	24%	0.239	S	C	.	.	H	α-helix	trans	-55.9	-42.9	-179.1	-78.1	-67.8	-178.7	0	0	113.5	I272 Y278 I279 V280 T421	I272-M276 HydrophobicContact CG2-CE 4.4Å; I272-M276 HydrophobicContact CG2-CG 3.96Å; I272-M276 WeakPolarHBondContact O-CB 3.28Å; I272-M276 WeakPolarHBondContact O-CG 3.45Å; I272-M276 PolarHBondContact O-N 3.05Å; M276-Y278 VanDerWaalsContact C-N 3.26Å; M276-Y278 PolarHBondContact O-N 3.24Å; M276-I279 PolarHBondContact O-N 3.47Å; M276-I279 VanDerWaalsContact O-N 3.11Å; M276-I279 HydrophobicContact SD-CD1 4.39Å; M276-V280 WeakPolarHBondContact O-CG2 3.41Å; M276-V280 PolarHBondContact O-N 3.35Å; M276-T421 HydrophobicContact CB-CG2 4.41Å
277	P	92.6	Very high	92.2	Very high	3 Å²	3	51.6 Å²	51.6	2%	0.019	25%	0.25	C	C	.	.	H	α-helix	trans	-57.9	-36.6	179.2	-28	36.7	0	0	0	113.8	T273 V280 L281 M418 L422	T273-P277 WeakPolarHBondContact O-CD 3.44Å; T273-P277 WeakPolarHBondContact O-CG 3.28Å; P277-V280 PolarHBondContact O-N 3.37Å; P277-L281 VanDerWaalsContact O-CB 3.29Å; P277-L281 WeakPolarHBondContact O-CB 3.35Å; P277-L281 VanDerWaalsContact O-CG 3.22Å; P277-L281 WeakPolarHBondContact O-CG 3.33Å; P277-L281 PolarHBondContact O-N 3.37Å; P277-M418 HydrophobicContact CB-CG 4.01Å; P277-L422 HydrophobicContact CB-CD1 4.31Å; P277-L422 HydrophobicContact CB-CD2 3.58Å; P277-L422 HydrophobicContact CB-CG 3.79Å; P277-L422 HydrophobicContact CG-CD2 3.56Å; P277-L422 HydrophobicContact CG-CG 3.62Å
278	Y	92.9	Very high	92.3	Very high	75 Å²	75	51.5 Å²	51.5	29%	0.294	25%	0.249	S	C	.	.	H	α-helix	trans	-65.8	-40.2	177.6	-66.2	-80.2	0	0	0	112.5	I78 A274 T275 M276 F282 V356 T360	I78-Y278 HydrophobicContact CG2-CE2 4.34Å; I78-Y278 WeakPolarHBondContact CG2-OH 3.36Å; A274-Y278 WeakPolarHBondContact O-CD2 3.46Å; A274-Y278 WeakPolarHBondContact O-CE2 3.33Å; T275-Y278 PolarHBondContact O-N 3.46Å; M276-Y278 VanDerWaalsContact C-N 3.26Å; M276-Y278 PolarHBondContact O-N 3.24Å; Y278-F282 VanDerWaalsContact O-CB 3.29Å; Y278-F282 WeakPolarHBondContact O-CB 3.37Å; Y278-F282 PolarHBondContact O-N 3.34Å; Y278-V356 HydrophobicContact CE1-CG1 4.49Å; Y278-V356 VanDerWaalsContact OH-CG1 3.3Å; Y278-V356 WeakPolarHBondContact OH-CG1 3.27Å; Y278-T360 HydrophobicContact CE1-CG2 4.05Å; Y278-T360 VanDerWaalsContact CE1-OG1 3.25Å; Y278-T360 WeakPolarHBondContact CE1-OG1 3.22Å; Y278-T360 PolarHBondContact OH-OG1 3.42Å
279	I	93.5	Very high	92.4	Very high	98 Å²	98	48.1 Å²	48.1	50%	0.503	24%	0.238	S	C	.	.	H	α-helix	trans	-63.2	-48.1	176.1	-59.9	173.9	0	0	0	109.1	T275 M276 F282 V283	T275-I279 PolarHBondContact O-N 3.01Å; M276-I279 PolarHBondContact O-N 3.47Å; M276-I279 VanDerWaalsContact O-N 3.11Å; M276-I279 HydrophobicContact SD-CD1 4.39Å; I279-F282 PolarHBondContact O-N 2.86Å; I279-V283 VanDerWaalsContact O-CG2 3.32Å; I279-V283 WeakPolarHBondContact O-CG2 3.3Å; I279-V283 PolarHBondContact O-N 3.21Å
280	V	91.6	Very high	92.4	Very high	9 Å²	9	50.3 Å²	50.3	6%	0.055	25%	0.251	C	S	.	.	H	α-helix	trans	-65.4	-46.7	-178.5	177	0	0	0	0	111.8	M276 P277 F282 V283 L284 V414 M418	M276-V280 WeakPolarHBondContact O-CG2 3.41Å; M276-V280 PolarHBondContact O-N 3.35Å; P277-V280 PolarHBondContact O-N 3.37Å; V280-F282 VanDerWaalsContact C-N 3.27Å; V280-F282 PolarHBondContact O-N 2.81Å; V280-V283 PolarHBondContact O-N 3.14Å; V280-L284 HydrophobicContact CG1-CD1 3.7Å; V280-L284 HydrophobicContact CG1-CG 4.05Å; V280-L284 WeakPolarHBondContact O-CB 3.41Å; V280-L284 WeakPolarHBondContact O-CG 3.3Å; V280-L284 PolarHBondContact O-N 2.77Å; V280-V414 HydrophobicContact CB-CG1 4.09Å; V280-V414 HydrophobicContact CG1-CG1 3.64Å; V280-V414 HydrophobicContact CG2-CG1 3.43Å; V280-V414 VanDerWaalsContact CG2-CG1 3.43Å; V280-M418 HydrophobicContact CB-CB 3.86Å; V280-M418 HydrophobicContact CB-CG 4.18Å; V280-M418 HydrophobicContact CB-SD 3.88Å; V280-M418 HydrophobicContact CG1-CB 3.72Å; V280-M418 HydrophobicContact CG1-CE 4.43Å; V280-M418 HydrophobicContact CG1-CG 4.17Å; V280-M418 HydrophobicContact CG1-SD 3.56Å; V280-M418 VanDerWaalsContact CG1-SD 3.56Å; V280-M418 HydrophobicContact CG2-CB 4.06Å
281	L	91	Very high	92.3	Very high	3 Å²	3	50.6 Å²	50.6	2%	0.016	25%	0.253	C	S	.	.	H	α-helix	trans	-58.6	-40.5	176.8	-74.7	174.5	0	0	0	111.6	P277 L285 T360 F363 M418	P277-L281 VanDerWaalsContact O-CB 3.29Å; P277-L281 WeakPolarHBondContact O-CB 3.35Å; P277-L281 VanDerWaalsContact O-CG 3.22Å; P277-L281 WeakPolarHBondContact O-CG 3.33Å; P277-L281 PolarHBondContact O-N 3.37Å; L281-L285 WeakPolarHBondContact O-CB 3.32Å; L281-L285 PolarHBondContact O-N 3.08Å; L281-T360 HydrophobicContact CD1-CG2 4.08Å; L281-F363 HydrophobicContact CB-CD1 4.27Å; L281-F363 HydrophobicContact CB-CE1 4.12Å; L281-M418 HydrophobicContact CD2-CE 4.43Å; L281-M418 HydrophobicContact CD2-SD 3.77Å; L281-M418 HydrophobicContact CG-SD 3.79Å
282	F	92.6	Very high	92.2	Very high	116 Å²	116	50.5 Å²	50.5	51%	0.509	26%	0.262	S	S	.	.	H	α-helix	trans	-64.8	-45.3	177.4	-178.2	-104	0	0	0	112.1	Y278 I279 V280 L285 I286 F363	Y278-F282 VanDerWaalsContact O-CB 3.29Å; Y278-F282 WeakPolarHBondContact O-CB 3.37Å; Y278-F282 PolarHBondContact O-N 3.34Å; I279-F282 PolarHBondContact O-N 2.86Å; V280-F282 VanDerWaalsContact C-N 3.27Å; V280-F282 PolarHBondContact O-N 2.81Å; F282-L285 PolarHBondContact O-N 3.04Å; F282-I286 HydrophobicContact CD1-CD1 3.91Å; F282-I286 HydrophobicContact CE1-CD1 3.39Å; F282-I286 HydrophobicContact CE1-CG1 4.47Å; F282-I286 HydrophobicContact CE2-CD1 4.36Å; F282-I286 HydrophobicContact CZ-CD1 3.65Å; F282-I286 HydrophobicContact CZ-CG1 4.45Å; F282-I286 WeakPolarHBondContact O-CG1 3.29Å; F282-I286 PolarHBondContact O-N 2.86Å; F282-I286 VanDerWaalsContact O-N 3.08Å; F282-F363 HydrophobicContact CD2-CZ 4.03Å
283	V	91.8	Very high	92.1	Very high	56 Å²	56	46.3 Å²	46.3	34%	0.339	25%	0.245	S	C	.	.	H	α-helix	trans	-66.6	-42.1	177.7	179.2	0	0	0	0	111.1	I279 V280 L285 I286 R287 W411	I279-V283 VanDerWaalsContact O-CG2 3.32Å; I279-V283 WeakPolarHBondContact O-CG2 3.3Å; I279-V283 PolarHBondContact O-N 3.21Å; V280-V283 PolarHBondContact O-N 3.14Å; V283-L285 VanDerWaalsContact C-N 3.31Å; V283-L285 PolarHBondContact O-N 3.04Å; V283-I286 PolarHBondContact O-N 3.44Å; V283-R287 WeakPolarHBondContact O-CB 3.22Å; V283-R287 PolarHBondContact O-N 3.4Å; V283-W411 HydrophobicContact CG1-CH2 3.85Å; V283-W411 HydrophobicContact CG1-CZ3 3.72Å
284	L	88.2	Confident	92	Very high	17 Å²	17	46.4 Å²	46.4	9%	0.089	25%	0.246	C	C	.	.	H	α-helix	trans	-63.8	-36	175.4	-73.8	177.2	0	0	0	111.9	V280 R287 G288 W411 F415 M418	V280-L284 HydrophobicContact CG1-CD1 3.7Å; V280-L284 HydrophobicContact CG1-CG 4.05Å; V280-L284 WeakPolarHBondContact O-CB 3.41Å; V280-L284 WeakPolarHBondContact O-CG 3.3Å; V280-L284 PolarHBondContact O-N 2.77Å; L284-R287 PolarHBondContact O-N 3.21Å; L284-G288 WeakPolarHBondContact O-CA 3.38Å; L284-G288 PolarHBondContact O-N 3.4Å; L284-W411 HydrophobicContact CD2-CE3 3.93Å; L284-W411 HydrophobicContact CD2-CZ3 4.15Å; L284-F415 HydrophobicContact CD1-CD2 3.98Å; L284-M418 HydrophobicContact CD1-CE 4.21Å; L284-M418 HydrophobicContact CD1-SD 4.46Å
285	L	91.8	Very high	92	Very high	22 Å²	22	51.4 Å²	51.4	12%	0.115	27%	0.27	C	S	.	.	H	α-helix	trans	-64.5	-49.1	174.8	179.3	65.4	0	0	0	111.6	L281 F282 V283 R287 G288 I289 F363 F366 A367	L281-L285 WeakPolarHBondContact O-CB 3.32Å; L281-L285 PolarHBondContact O-N 3.08Å; F282-L285 PolarHBondContact O-N 3.04Å; V283-L285 VanDerWaalsContact C-N 3.31Å; V283-L285 PolarHBondContact O-N 3.04Å; L285-R287 VanDerWaalsContact C-N 3.29Å; L285-R287 PolarHBondContact O-N 3.05Å; L285-G288 PolarHBondContact O-N 2.8Å; L285-I289 HydrophobicContact CD1-CD1 3.63Å; L285-I289 HydrophobicContact CD1-CG1 3.96Å; L285-I289 HydrophobicContact CD2-CD1 4.49Å; L285-I289 HydrophobicContact CG-CD1 3.9Å; L285-I289 HydrophobicContact CG-CG1 4.47Å; L285-I289 WeakPolarHBondContact O-CG1 3.35Å; L285-I289 PolarHBondContact O-N 3.49Å; L285-F363 HydrophobicContact CB-CE1 4.29Å; L285-F363 HydrophobicContact CB-CZ 4.06Å; L285-F363 HydrophobicContact CD2-CD2 4.04Å; L285-F363 HydrophobicContact CD2-CE1 4.04Å; L285-F363 HydrophobicContact CD2-CE2 3.18Å; L285-F363 HydrophobicContact CD2-CZ 3.18Å; L285-F363 HydrophobicContact CG-CZ 4.22Å; L285-F366 HydrophobicContact CD1-CB 3.51Å; L285-A367 HydrophobicContact CB-CB 4.23Å; L285-A367 HydrophobicContact CD1-CB 4.44Å
286	I	92.7	Very high	91.8	Very high	89 Å²	89	53.6 Å²	53.6	46%	0.456	28%	0.276	S	S	.	.	H	α-helix	trans	-57.3	-49	177.6	-68.5	170.6	0	0	0	109.1	F282 V283 T290	F282-I286 HydrophobicContact CD1-CD1 3.91Å; F282-I286 HydrophobicContact CE1-CD1 3.39Å; F282-I286 HydrophobicContact CE1-CG1 4.47Å; F282-I286 HydrophobicContact CE2-CD1 4.36Å; F282-I286 HydrophobicContact CZ-CD1 3.65Å; F282-I286 HydrophobicContact CZ-CG1 4.45Å; F282-I286 WeakPolarHBondContact O-CG1 3.29Å; F282-I286 PolarHBondContact O-N 2.86Å; F282-I286 VanDerWaalsContact O-N 3.08Å; V283-I286 PolarHBondContact O-N 3.44Å; I286-T290 VanDerWaalsContact O-CG2 3.22Å; I286-T290 WeakPolarHBondContact O-CG2 3.31Å; I286-T290 PolarHBondContact O-N 2.85Å; I286-T290 PolarHBondContact O-OG1 3.35Å
287	R	90.4	Very high	91.8	Very high	62 Å²	62	50.1 Å²	50.1	23%	0.234	26%	0.259	C	S	.	.	H	α-helix	trans	-62.3	-47.3	179.1	-178.3	56.7	-176.7	147	-2.7	111.5	V283 L284 L285 I289 T290 L291 L405 W411	V283-R287 WeakPolarHBondContact O-CB 3.22Å; V283-R287 PolarHBondContact O-N 3.4Å; L284-R287 PolarHBondContact O-N 3.21Å; L285-R287 VanDerWaalsContact C-N 3.29Å; L285-R287 PolarHBondContact O-N 3.05Å; R287-I289 PolarHBondContact O-N 3.03Å; R287-T290 PolarHBondContact NH1-OG1 3.35Å; R287-T290 PolarHBondContact O-N 3.04Å; R287-T290 VanDerWaalsContact O-N 3.15Å; R287-T290 PolarHBondContact O-OG1 3.03Å; R287-L291 WeakPolarHBondContact O-CG 3.29Å; R287-L291 PolarHBondContact O-N 2.81Å; R287-L405 HydrophobicContact CG-CD1 4.39Å; R287-W411 HydrophobicContact CB-CH2 3.68Å; R287-W411 HydrophobicContact CB-CZ2 4.26Å; R287-W411 HydrophobicContact CB-CZ3 4.03Å; R287-W411 HydrophobicContact CG-CH2 3.78Å; R287-W411 HydrophobicContact CG-CZ2 3.86Å; R287-W411 HydrophobicContact CG-CZ3 4.22Å
288	G	90.7	Very high	91.8	Very high	0 Å²	0	51 Å²	51	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-59.1	-45.4	-178.3	0	0	0	0	0	112.7	L284 L285 T290 L291 S294 S370	L284-G288 WeakPolarHBondContact O-CA 3.38Å; L284-G288 PolarHBondContact O-N 3.4Å; L285-G288 PolarHBondContact O-N 2.8Å; G288-T290 VanDerWaalsContact C-N 3.3Å; G288-T290 PolarHBondContact O-N 3.23Å; G288-L291 WeakPolarHBondContact O-CB 3.2Å; G288-L291 PolarHBondContact O-N 3.48Å; G288-S294 WeakPolarHBondContact O-CB 3.28Å; G288-S370 WeakPolarHBondContact CA-OG 3.45Å
289	I	94.6	Very high	91.8	Very high	86 Å²	86	54.1 Å²	54.1	44%	0.441	28%	0.279	S	S	.	.	H	α-helix	trans	-65.7	-33.1	177.3	-68.4	175.2	0	0	0	111.7	L285 R287 L291 S294 I298	L285-I289 HydrophobicContact CD1-CD1 3.63Å; L285-I289 HydrophobicContact CD1-CG1 3.96Å; L285-I289 HydrophobicContact CD2-CD1 4.49Å; L285-I289 HydrophobicContact CG-CD1 3.9Å; L285-I289 HydrophobicContact CG-CG1 4.47Å; L285-I289 WeakPolarHBondContact O-CG1 3.35Å; L285-I289 PolarHBondContact O-N 3.49Å; R287-I289 PolarHBondContact O-N 3.03Å; I289-L291 PolarHBondContact O-N 3.38Å; I289-S294 PolarHBondContact O-OG 2.87Å; I289-I298 HydrophobicContact CG1-CD1 4.25Å
290	T	93.1	Very high	91.6	Very high	87 Å²	87	50.3 Å²	50.3	53%	0.534	26%	0.262	S	S	.	.	T	Hydrogen-bonded Turn	trans	-72.8	-10.8	177.4	65.2	0	0	0	0	114.4	I286 R287 G288	I286-T290 VanDerWaalsContact O-CG2 3.22Å; I286-T290 WeakPolarHBondContact O-CG2 3.31Å; I286-T290 PolarHBondContact O-N 2.85Å; I286-T290 PolarHBondContact O-OG1 3.35Å; R287-T290 PolarHBondContact NH1-OG1 3.35Å; R287-T290 PolarHBondContact O-N 3.04Å; R287-T290 VanDerWaalsContact O-N 3.15Å; R287-T290 PolarHBondContact O-OG1 3.03Å; G288-T290 VanDerWaalsContact C-N 3.3Å; G288-T290 PolarHBondContact O-N 3.23Å
291	L	91.9	Very high	91.7	Very high	10 Å²	10	50 Å²	50	5%	0.052	26%	0.259	C	S	.	.	S	Bend	trans	-77.2	146.9	178.9	-67.9	169.9	0	0	0	111.5	R287 G288 I289 S294 Y374 L405	R287-L291 WeakPolarHBondContact O-CG 3.29Å; R287-L291 PolarHBondContact O-N 2.81Å; G288-L291 WeakPolarHBondContact O-CB 3.2Å; G288-L291 PolarHBondContact O-N 3.48Å; I289-L291 PolarHBondContact O-N 3.38Å; L291-S294 WeakPolarHBondContact O-CB 3.13Å; L291-S294 PolarHBondContact O-N 3.11Å; L291-S294 PolarHBondContact O-OG 3.35Å; L291-S294 VanDerWaalsContact O-OG 3.1Å; L291-Y374 HydrophobicContact CB-CD2 3.85Å; L291-Y374 HydrophobicContact CB-CG 3.82Å; L291-Y374 HydrophobicContact CD1-CD1 3.81Å; L291-Y374 HydrophobicContact CD1-CD2 4.44Å; L291-Y374 HydrophobicContact CD1-CE1 4.37Å; L291-Y374 HydrophobicContact CD1-CG 3.83Å; L291-Y374 HydrophobicContact CD2-CD2 4.26Å; L291-Y374 HydrophobicContact CD2-CE2 4.27Å; L291-Y374 HydrophobicContact CD2-CG 4.45Å; L291-Y374 HydrophobicContact CG-CD2 4.4Å; L291-Y374 HydrophobicContact CG-CG 4.24Å; L291-L405 HydrophobicContact CD1-CD2 3.87Å; L291-L405 HydrophobicContact CD2-CD2 3.53Å; L291-L405 HydrophobicContact CG-CD2 4.33Å
292	P	91.8	Very high	91.8	Very high	81 Å²	81	52.6 Å²	52.6	53%	0.526	27%	0.273	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.9	139.7	173.3	27.1	-31.9	0	0	0	109.5	S294 Y374 Q377	P292-S294 PolarHBondContact O-N 3.5Å; P292-Y374 HydrophobicContact CG-CD2 3.84Å; P292-Y374 HydrophobicContact CG-CE2 4.02Å; P292-Y374 VanDerWaalsContact O-CA 3.25Å; P292-Y374 WeakPolarHBondContact O-CA 3.36Å; P292-Y374 WeakPolarHBondContact O-CB 3.43Å; P292-Y374 WeakPolarHBondContact O-CD2 3.34Å; P292-Q377 PolarHBondContact O-OE1 3.41Å
293	G	89.6	Confident	91.7	Very high	16 Å²	16	52.1 Å²	52.1	17%	0.165	28%	0.276	C	S	.	.	T	Hydrogen-bonded Turn	trans	82.6	-4	175.8	0	0	0	0	0	114.7	M295 E296 G373	G293-M295 PolarHBondContact O-N 3.06Å; G293-M295 VanDerWaalsContact O-N 3.12Å; G293-E296 WeakPolarHBondContact O-CB 3.06Å; G293-E296 PolarHBondContact O-N 3.22Å; G293-G373 CarbonylContact O-C 3.5Å; G293-G373 VanDerWaalsContact O-C 3.28Å; G293-G373 WeakPolarHBondContact O-CA 3.33Å
294	S	92.6	Very high	91.8	Very high	12 Å²	12	54.3 Å²	54.3	8%	0.084	29%	0.285	C	S	.	.	H	α-helix	trans	-53.7	-35.1	176.7	64.7	0	0	0	0	113.1	G288 I289 L291 P292 E296 G297 I298 S370	G288-S294 WeakPolarHBondContact O-CB 3.28Å; I289-S294 PolarHBondContact O-OG 2.87Å; L291-S294 WeakPolarHBondContact O-CB 3.13Å; L291-S294 PolarHBondContact O-N 3.11Å; L291-S294 PolarHBondContact O-OG 3.35Å; L291-S294 VanDerWaalsContact O-OG 3.1Å; P292-S294 PolarHBondContact O-N 3.5Å; S294-E296 VanDerWaalsContact C-N 3.33Å; S294-E296 PolarHBondContact O-N 3.42Å; S294-G297 PolarHBondContact O-N 3.24Å; S294-I298 WeakPolarHBondContact O-CG1 3.32Å; S294-I298 PolarHBondContact O-N 3.2Å; S294-S370 WeakPolarHBondContact CA-O 3.45Å
295	M	92.6	Very high	92	Very high	109 Å²	109	55.8 Å²	55.8	54%	0.537	29%	0.293	S	S	.	.	H	α-helix	trans	-65.1	-31.9	177.9	-171.2	58.3	62.8	0	0	113.2	G293 I298 K299	G293-M295 PolarHBondContact O-N 3.06Å; G293-M295 VanDerWaalsContact O-N 3.12Å; M295-I298 PolarHBondContact O-N 2.98Å; M295-K299 HydrophobicContact CG-CD 4.36Å; M295-K299 WeakPolarHBondContact O-CB 3.33Å; M295-K299 VanDerWaalsContact O-CG 3.24Å; M295-K299 WeakPolarHBondContact O-CG 3.46Å; M295-K299 PolarHBondContact O-N 3.31Å
296	E	90.3	Very high	92.1	Very high	101 Å²	101	60.8 Å²	60.8	47%	0.472	31%	0.314	S	S	.	.	H	α-helix	trans	-67.7	-40.9	177.1	-64.6	-171.6	167.5	0	0	111.1	G293 S294 K299 A300	G293-E296 WeakPolarHBondContact O-CB 3.06Å; G293-E296 PolarHBondContact O-N 3.22Å; S294-E296 VanDerWaalsContact C-N 3.33Å; S294-E296 PolarHBondContact O-N 3.42Å; E296-K299 PolarHBondContact O-N 2.86Å; E296-A300 WeakPolarHBondContact O-CB 3.45Å; E296-A300 PolarHBondContact O-N 2.98Å
297	G	91.6	Very high	92.2	Very high	0 Å²	0	62.1 Å²	62.1	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-65.7	-43.2	174.3	0	0	0	0	0	112.7	S294 K299 A300 Y301 F369	S294-G297 PolarHBondContact O-N 3.24Å; G297-K299 VanDerWaalsContact C-N 3.34Å; G297-K299 PolarHBondContact O-N 3Å; G297-A300 WeakPolarHBondContact O-CB 3.49Å; G297-A300 PolarHBondContact O-N 3.28Å; G297-A300 VanDerWaalsContact O-N 3.15Å; G297-Y301 PolarHBondContact O-N 2.84Å; G297-F369 VanDerWaalsContact CA-O 3.29Å; G297-F369 WeakPolarHBondContact CA-O 3.42Å; G297-F369 WeakPolarHBondContact O-CD1 3.22Å
298	I	93.4	Very high	92.2	Very high	23 Å²	23	64.8 Å²	64.8	12%	0.118	33%	0.332	C	S	.	.	H	α-helix	trans	-63.8	-40.3	176.1	-65.6	169.1	0	0	0	111.2	I289 S294 M295 A300 Y301 L302 F366	I289-I298 HydrophobicContact CG1-CD1 4.25Å; S294-I298 WeakPolarHBondContact O-CG1 3.32Å; S294-I298 PolarHBondContact O-N 3.2Å; M295-I298 PolarHBondContact O-N 2.98Å; I298-A300 VanDerWaalsContact C-N 3.32Å; I298-A300 PolarHBondContact O-N 3.19Å; I298-Y301 WeakPolarHBondContact O-CB 3.25Å; I298-Y301 PolarHBondContact O-N 3.22Å; I298-L302 HydrophobicContact CG2-CD1 4.32Å; I298-L302 PolarHBondContact O-N 3.42Å; I298-F366 HydrophobicContact CG1-CD1 4.39Å; I298-F366 HydrophobicContact CG2-CD1 4.17Å; I298-F366 HydrophobicContact CG2-CE1 4.06Å
299	K	92.2	Very high	92.2	Very high	140 Å²	140	66.1 Å²	66.1	61%	0.609	34%	0.339	S	S	*	.	H	α-helix	trans	-61.1	-42	172.9	-77.7	174	179.9	178	0	111.3	M295 E296 G297 N303	M295-K299 HydrophobicContact CG-CD 4.36Å; M295-K299 WeakPolarHBondContact O-CB 3.33Å; M295-K299 VanDerWaalsContact O-CG 3.24Å; M295-K299 WeakPolarHBondContact O-CG 3.46Å; M295-K299 PolarHBondContact O-N 3.31Å; E296-K299 PolarHBondContact O-N 2.86Å; G297-K299 VanDerWaalsContact C-N 3.34Å; G297-K299 PolarHBondContact O-N 3Å; K299-N303 WeakPolarHBondContact O-CA 3.45Å; K299-N303 VanDerWaalsContact O-CB 3.29Å; K299-N303 WeakPolarHBondContact O-CB 3.21Å; K299-N303 PolarHBondContact O-N 3.4Å
300	A	89.9	Confident	92	Very high	18 Å²	18	68.6 Å²	68.6	15%	0.149	35%	0.353	C	S	.	.	H	α-helix	trans	-62.2	-42.7	175.3	0	0	0	0	0	111.8	Y95 E296 G297 I298 V383	Y95-A300 HydrophobicContact CD2-CB 4.16Å; Y95-A300 WeakPolarHBondContact CD2-O 3.42Å; Y95-A300 HydrophobicContact CE2-CB 3.83Å; E296-A300 WeakPolarHBondContact O-CB 3.45Å; E296-A300 PolarHBondContact O-N 2.98Å; G297-A300 WeakPolarHBondContact O-CB 3.49Å; G297-A300 PolarHBondContact O-N 3.28Å; G297-A300 VanDerWaalsContact O-N 3.15Å; I298-A300 VanDerWaalsContact C-N 3.32Å; I298-A300 PolarHBondContact O-N 3.19Å; A300-V383 HydrophobicContact CB-CB 4.16Å; A300-V383 HydrophobicContact CB-CG1 3.86Å; A300-V383 HydrophobicContact CB-CG2 4.28Å
301	Y	92.6	Very high	91.8	Very high	1 Å²	1	68.2 Å²	68.2	0%	0.004	35%	0.348	C	S	.	.	H	α-helix	trans	-62.5	-44.3	178.4	179.8	-131.7	0	0	0	113.4	F90 C94 G99 G297 I298 F362 F366 F369	F90-Y301 WeakPolarHBondContact CE1-OH 3.21Å; C94-Y301 HydrophobicContact CB-CD2 3.99Å; C94-Y301 HydrophobicContact CB-CE2 3.48Å; C94-Y301 VanDerWaalsContact CB-CE2 3.48Å; G99-Y301 CarbonylContact C-O 3.03Å; G99-Y301 WeakPolarHBondContact CA-O 3.22Å; G297-Y301 PolarHBondContact O-N 2.84Å; I298-Y301 WeakPolarHBondContact O-CB 3.25Å; I298-Y301 PolarHBondContact O-N 3.22Å; Y301-F362 HydrophobicContact CE1-CD2 4.41Å; Y301-F362 HydrophobicContact CE1-CE2 4.27Å; Y301-F362 WeakPolarHBondContact OH-CD2 3.36Å; Y301-F366 HydrophobicContact CE1-CD2 4.21Å; Y301-F366 HydrophobicContact CE1-CE2 4.19Å; Y301-F366 HydrophobicContact CE1-CZ 4.49Å; Y301-F369 AromaticContact CD2-CD2 3.67Å; Y301-F369 HydrophobicContact CD2-CD2 3.67Å; Y301-F369 AromaticContact CD2-CE2 3.89Å; Y301-F369 HydrophobicContact CD2-CE2 3.89Å; Y301-F369 HydrophobicContact CD2-CG 4.22Å; Y301-F369 HydrophobicContact CE2-CD2 4.45Å; Y301-F369 HydrophobicContact CG-CB 4.28Å; Y301-F369 AromaticContact CG-CD2 3.9Å; Y301-F369 HydrophobicContact CG-CD2 3.9Å; Y301-F369 HydrophobicContact CG-CG 4.03Å
302	L	92.9	Very high	91.5	Very high	59 Å²	59	71.6 Å²	71.6	31%	0.309	37%	0.365	S	S	.	.	H	α-helix	trans	-102	8.4	-174.8	-62.8	-179.3	0	0	0	114	I298 I304 F362 F366	I298-L302 HydrophobicContact CG2-CD1 4.32Å; I298-L302 PolarHBondContact O-N 3.42Å; L302-I304 WeakPolarHBondContact O-CG1 3.23Å; L302-I304 PolarHBondContact O-N 3.2Å; L302-F362 HydrophobicContact CD2-CE2 4.04Å; L302-F362 HydrophobicContact CD2-CZ 4.47Å; L302-F366 HydrophobicContact CD1-CE1 3.73Å; L302-F366 HydrophobicContact CD1-CZ 3.76Å
303	N	91.9	Very high	91.2	Very high	105 Å²	105	73 Å²	73	56%	0.561	37%	0.365	S	S	*	.			trans	-58.3	134.9	175.7	-171.1	23.5	0	0	0	109.3	G98 G99 G100 K299	G98-N303 CarbonylContact C-O 3.6Å; G99-N303 CarbonylContact C-O 3.56Å; G99-N303 WeakPolarHBondContact CA-O 3.1Å; G100-N303 PolarHBondContact N-O 3.33Å; K299-N303 WeakPolarHBondContact O-CA 3.45Å; K299-N303 VanDerWaalsContact O-CB 3.29Å; K299-N303 WeakPolarHBondContact O-CB 3.21Å; K299-N303 PolarHBondContact O-N 3.4Å
304	I	93.9	Very high	91.2	Very high	102 Å²	102	72.3 Å²	72.3	52%	0.523	36%	0.358	S	S	.	.	B	Isolated β-bridge	trans	-104.4	106.2	-174.5	-55.8	177.9	0	0	0	108.4	A101 L302 F306	A101-I304 HydrophobicContact CB-CG2 4.28Å; L302-I304 WeakPolarHBondContact O-CG1 3.23Å; L302-I304 PolarHBondContact O-N 3.2Å; I304-F306 HydrophobicContact CG2-CD1 4.5Å; I304-F306 HydrophobicContact CG2-CD2 3.89Å; I304-F306 HydrophobicContact CG2-CE1 4.08Å; I304-F306 HydrophobicContact CG2-CE2 3.4Å; I304-F306 HydrophobicContact CG2-CG 4.41Å; I304-F306 HydrophobicContact CG2-CZ 3.51Å
305	D	92.4	Very high	91	Very high	49 Å²	49	75.5 Å²	75.5	26%	0.262	37%	0.368	S	S	.	.			trans	-118.5	94.2	173.3	-176	7.7	0	0	0	110.9	G98 N307 R308	G98-D305 PolarHBondContact O-N 2.96Å; D305-N307 PolarHBondContact O-N 2.72Å; D305-N307 WeakPolarHBondContact OD1-CB 3.36Å; D305-N307 PolarHBondContact OD1-N 3.4Å; D305-N307 VanDerWaalsContact OD1-N 3.12Å; D305-N307 PolarHBondContact OD1-ND2 3.42Å; D305-N307 VanDerWaalsContact OD1-ND2 3.08Å; D305-R308 HydrophobicContact CB-CG 4.28Å; D305-R308 PolarHBondContact O-N 3.39Å; D305-R308 WeakPolarHBondContact OD2-CG 3.24Å; D305-R308 IonicContact OD2-NE 2.58Å
306	F	93.4	Very high	90.6	Very high	126 Å²	126	71.3 Å²	71.3	55%	0.553	35%	0.348	S	S	*	.	G	3₁₀ helix	trans	-64.9	-21.4	179.8	-68.5	-71.1	0	0	0	113.4	A101 I104 I304 R308 L309	A101-F306 HydrophobicContact CB-CD1 4.43Å; I104-F306 HydrophobicContact CD1-CE1 3.91Å; I304-F306 HydrophobicContact CG2-CD1 4.5Å; I304-F306 HydrophobicContact CG2-CD2 3.89Å; I304-F306 HydrophobicContact CG2-CE1 4.08Å; I304-F306 HydrophobicContact CG2-CE2 3.4Å; I304-F306 HydrophobicContact CG2-CG 4.41Å; I304-F306 HydrophobicContact CG2-CZ 3.51Å; F306-R308 PolarHBondContact O-N 3.03Å; F306-L309 HydrophobicContact CD1-CD1 3.94Å; F306-L309 WeakPolarHBondContact O-CB 3.02Å; F306-L309 PolarHBondContact O-N 3.2Å; F306-L309 VanDerWaalsContact O-N 3.11Å
307	N	93.6	Very high	90.5	Very high	118 Å²	118	67.6 Å²	67.6	63%	0.631	33%	0.331	S	S	*	.	G	3₁₀ helix	trans	-65	-28.1	-179.8	-60.2	-57.1	0	0	0	111.6	D305 L309 N310	D305-N307 PolarHBondContact O-N 2.72Å; D305-N307 WeakPolarHBondContact OD1-CB 3.36Å; D305-N307 PolarHBondContact OD1-N 3.4Å; D305-N307 VanDerWaalsContact OD1-N 3.12Å; D305-N307 PolarHBondContact OD1-ND2 3.42Å; D305-N307 VanDerWaalsContact OD1-ND2 3.08Å; N307-L309 PolarHBondContact O-N 3.02Å; N307-N310 WeakPolarHBondContact O-CB 3.47Å; N307-N310 PolarHBondContact O-N 3.04Å
308	R	90.4	Very high	90.4	Very high	118 Å²	118	67.6 Å²	67.6	45%	0.445	33%	0.331	S	S	.	.	G	3₁₀ helix	trans	-64.1	-29.1	176.6	-67.4	-69.5	-178.9	165.6	2	112.5	D305 F306 N310 N311 V314	D305-R308 HydrophobicContact CB-CG 4.28Å; D305-R308 PolarHBondContact O-N 3.39Å; D305-R308 WeakPolarHBondContact OD2-CG 3.24Å; D305-R308 IonicContact OD2-NE 2.58Å; F306-R308 PolarHBondContact O-N 3.03Å; R308-N310 PolarHBondContact O-N 3.12Å; R308-N311 WeakPolarHBondContact O-CB 3.44Å; R308-N311 PolarHBondContact O-N 2.95Å; R308-V314 HydrophobicContact CB-CG2 4.48Å; R308-V314 VanDerWaalsContact O-CG2 3.22Å; R308-V314 WeakPolarHBondContact O-CG2 3.23Å
309	L	91.2	Very high	90	Very high	27 Å²	27	66.5 Å²	66.5	14%	0.141	33%	0.325	C	S	.	.	G	3₁₀ helix	trans	-66.4	-17.4	179.4	-60.8	-178.3	0	0	0	113.6	A101 I104 P105 F306 N307 N311 V314 W315	A101-L309 HydrophobicContact CB-CD1 4.35Å; A101-L309 HydrophobicContact CB-CD2 4.36Å; A101-L309 HydrophobicContact CB-CG 4.28Å; I104-L309 HydrophobicContact CD1-CD1 4.25Å; P105-L309 HydrophobicContact CG-CD2 4.01Å; F306-L309 HydrophobicContact CD1-CD1 3.94Å; F306-L309 WeakPolarHBondContact O-CB 3.02Å; F306-L309 PolarHBondContact O-N 3.2Å; F306-L309 VanDerWaalsContact O-N 3.11Å; N307-L309 PolarHBondContact O-N 3.02Å; L309-N311 PolarHBondContact O-N 2.89Å; L309-V314 HydrophobicContact CD2-CG1 4.08Å; L309-W315 PolarHBondContact O-NE1 3.26Å
310	N	91.3	Very high	89.6	Confident	138 Å²	138	60.6 Å²	60.6	74%	0.738	30%	0.301	S	S	*	.	G	3₁₀ helix	trans	-71.8	-16.8	173.8	-66.4	-28.8	0	0	0	112.6	N307 R308	N307-N310 WeakPolarHBondContact O-CB 3.47Å; N307-N310 PolarHBondContact O-N 3.04Å; R308-N310 PolarHBondContact O-N 3.12Å
311	N	89.3	Confident	89.7	Confident	79 Å²	79	59.8 Å²	59.8	42%	0.422	29%	0.294	S	S	.	.	S	Bend	trans	-84.3	125.2	178.3	-64.7	-34	0	0	0	110.6	R308 L309 E313 V314	R308-N311 WeakPolarHBondContact O-CB 3.44Å; R308-N311 PolarHBondContact O-N 2.95Å; L309-N311 PolarHBondContact O-N 2.89Å; N311-E313 PolarHBondContact O-N 3Å; N311-V314 HydrophobicContact CB-CG2 4.2Å; N311-V314 WeakPolarHBondContact O-CB 3.3Å; N311-V314 PolarHBondContact O-N 3.3Å; N311-V314 VanDerWaalsContact O-N 3.15Å
312	L	85.6	Confident	89.6	Confident	81 Å²	81	59.7 Å²	59.7	42%	0.424	29%	0.294	S	S	.	.	H	α-helix	trans	-59.5	-32.6	178.8	-178.5	61.7	0	0	0	112.9	V314 W315 I316 F538 A542	L312-V314 PolarHBondContact O-N 2.99Å; L312-W315 PolarHBondContact O-N 3Å; L312-W315 VanDerWaalsContact O-N 3.08Å; L312-I316 HydrophobicContact CD2-CD1 4.48Å; L312-I316 HydrophobicContact CG-CD1 4.11Å; L312-I316 HydrophobicContact CG-CG1 4.43Å; L312-I316 PolarHBondContact O-N 2.69Å; L312-I316 VanDerWaalsContact O-N 3.13Å; L312-F538 HydrophobicContact CD1-CE1 3.9Å; L312-F538 HydrophobicContact CD1-CZ 3.68Å; L312-A542 HydrophobicContact CD2-CB 4.49Å
313	E	85.2	Confident	89.2	Confident	111 Å²	111	57 Å²	57	52%	0.519	28%	0.279	S	S	.	.	H	α-helix	trans	-56.6	-35.6	178.2	-168.1	-177.8	163	0	0	112.3	K96 N311 W315 I316 D317	K96-E313 IonicContact NZ-OE1 3.31Å; K96-E313 PolarHBondContact NZ-OE1 3.23Å; N311-E313 PolarHBondContact O-N 3Å; E313-W315 VanDerWaalsContact C-N 3.28Å; E313-W315 PolarHBondContact O-N 3.21Å; E313-I316 PolarHBondContact O-N 3.25Å; E313-D317 WeakPolarHBondContact O-CB 3.49Å; E313-D317 PolarHBondContact O-N 3.44Å
314	V	90.1	Very high	88.8	Confident	2 Å²	2	53.5 Å²	53.5	1%	0.012	26%	0.259	C	S	.	.	H	α-helix	trans	-61.3	-39.4	178.3	173.2	0	0	0	0	111.7	N97 F102 P105 R308 L309 N311 L312 A318	N97-V314 HydrophobicContact CB-CB 4.35Å; N97-V314 HydrophobicContact CB-CG1 3.89Å; N97-V314 HydrophobicContact CB-CG2 3.85Å; F102-V314 HydrophobicContact CD2-CG1 3.97Å; F102-V314 HydrophobicContact CE2-CG1 4.49Å; P105-V314 HydrophobicContact CG-CG1 4.14Å; R308-V314 HydrophobicContact CB-CG2 4.48Å; R308-V314 VanDerWaalsContact O-CG2 3.22Å; R308-V314 WeakPolarHBondContact O-CG2 3.23Å; L309-V314 HydrophobicContact CD2-CG1 4.08Å; N311-V314 HydrophobicContact CB-CG2 4.2Å; N311-V314 WeakPolarHBondContact O-CB 3.3Å; N311-V314 PolarHBondContact O-N 3.3Å; N311-V314 VanDerWaalsContact O-N 3.15Å; L312-V314 PolarHBondContact O-N 2.99Å; V314-A318 WeakPolarHBondContact O-CB 3.41Å; V314-A318 PolarHBondContact O-N 3.4Å
315	W	87.9	Confident	88.7	Confident	79 Å²	79	48.7 Å²	48.7	30%	0.299	23%	0.234	S	C	.	.	H	α-helix	trans	-73.9	-38	178.3	-62.2	86.3	0	0	0	111.3	P105 L108 F109 L309 L312 E313 A318 A319	P105-W315 HydrophobicContact CB-CD2 3.99Å; P105-W315 HydrophobicContact CB-CE3 3.51Å; P105-W315 HydrophobicContact CB-CH2 4.28Å; P105-W315 HydrophobicContact CB-CZ3 3.68Å; L108-W315 HydrophobicContact CD2-CH2 4.46Å; L108-W315 HydrophobicContact CD2-CZ3 3.77Å; F109-W315 HydrophobicContact CE1-CE3 4.21Å; F109-W315 HydrophobicContact CE2-CB 4.24Å; F109-W315 AromaticContact CE2-CE3 3.91Å; F109-W315 HydrophobicContact CE2-CE3 3.91Å; F109-W315 WeakPolarHBondContact CE2-O 3.36Å; F109-W315 HydrophobicContact CZ-CB 4.13Å; F109-W315 HydrophobicContact CZ-CD2 4.39Å; F109-W315 AromaticContact CZ-CE3 3.48Å; F109-W315 HydrophobicContact CZ-CE3 3.48Å; F109-W315 VanDerWaalsContact CZ-CE3 3.48Å; F109-W315 HydrophobicContact CZ-CZ3 4.29Å; L309-W315 PolarHBondContact O-NE1 3.26Å; L312-W315 PolarHBondContact O-N 3Å; L312-W315 VanDerWaalsContact O-N 3.08Å; E313-W315 VanDerWaalsContact C-N 3.28Å; E313-W315 PolarHBondContact O-N 3.21Å; W315-A318 PolarHBondContact O-N 3.07Å; W315-A319 WeakPolarHBondContact O-CB 3.34Å; W315-A319 PolarHBondContact O-N 2.61Å
316	I	84	Confident	88.6	Confident	21 Å²	21	46.3 Å²	46.3	11%	0.108	22%	0.221	C	C	.	.	H	α-helix	trans	-64.7	-43.8	175.1	-62.4	171.9	0	0	0	110.6	L312 E313 A319 T320 A542	L312-I316 HydrophobicContact CD2-CD1 4.48Å; L312-I316 HydrophobicContact CG-CD1 4.11Å; L312-I316 HydrophobicContact CG-CG1 4.43Å; L312-I316 PolarHBondContact O-N 2.69Å; L312-I316 VanDerWaalsContact O-N 3.13Å; E313-I316 PolarHBondContact O-N 3.25Å; I316-A319 PolarHBondContact O-N 2.81Å; I316-T320 VanDerWaalsContact O-CB 3.29Å; I316-T320 WeakPolarHBondContact O-CB 3.42Å; I316-T320 PolarHBondContact O-N 2.93Å; I316-T320 PolarHBondContact O-OG1 3.1Å; I316-A542 HydrophobicContact CD1-CB 3.82Å; I316-A542 HydrophobicContact CG1-CB 4.36Å
317	D	87.2	Confident	88.3	Confident	23 Å²	23	40.5 Å²	40.5	12%	0.123	20%	0.197	C	C	.	.	H	α-helix	trans	-61.8	-45.8	177.6	-81	-8.2	0	0	0	111.2	L93 K96 N97 F102 E313 Q321	L93-D317 HydrophobicContact CD2-CB 4.15Å; K96-D317 IonicContact NZ-OD2 2.77Å; K96-D317 PolarHBondContact NZ-OD2 3.44Å; N97-D317 WeakPolarHBondContact ND2-CB 3.23Å; N97-D317 PolarHBondContact ND2-OD2 3.44Å; F102-D317 HydrophobicContact CE2-CB 4.42Å; E313-D317 WeakPolarHBondContact O-CB 3.49Å; E313-D317 PolarHBondContact O-N 3.44Å; D317-Q321 VanDerWaalsContact O-CB 3.22Å; D317-Q321 WeakPolarHBondContact O-CB 3.34Å; D317-Q321 PolarHBondContact O-N 2.51Å
318	A	90.3	Very high	88	Confident	0 Å²	0	34.9 Å²	34.9	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-63.1	-43	177.3	0	0	0	0	0	112.2	F102 P105 F109 V314 W315 I322	F102-A318 HydrophobicContact CD2-CB 4.4Å; F102-A318 HydrophobicContact CE2-CB 3.57Å; F102-A318 HydrophobicContact CZ-CB 3.8Å; P105-A318 HydrophobicContact CB-CB 3.92Å; P105-A318 HydrophobicContact CG-CB 4.24Å; F109-A318 HydrophobicContact CD2-CB 3.64Å; F109-A318 HydrophobicContact CE2-CB 3.79Å; V314-A318 WeakPolarHBondContact O-CB 3.41Å; V314-A318 PolarHBondContact O-N 3.4Å; W315-A318 PolarHBondContact O-N 3.07Å; A318-I322 WeakPolarHBondContact O-CG1 3.24Å; A318-I322 PolarHBondContact O-N 2.95Å; A318-I322 VanDerWaalsContact O-N 3.11Å
319	A	85.6	Confident	87.8	Confident	0 Å²	0	29.2 Å²	29.2	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-62.5	-52.2	178.2	0	0	0	0	0	111.1	F109 W315 I316 Q321 I322 F323 F535 V539	F109-A319 HydrophobicContact CD2-CB 3.97Å; F109-A319 HydrophobicContact CE2-CB 3.98Å; F109-A319 HydrophobicContact CG-CB 4.48Å; F109-A319 HydrophobicContact CZ-CB 4.47Å; W315-A319 WeakPolarHBondContact O-CB 3.34Å; W315-A319 PolarHBondContact O-N 2.61Å; I316-A319 PolarHBondContact O-N 2.81Å; A319-Q321 VanDerWaalsContact C-N 3.31Å; A319-Q321 PolarHBondContact O-N 2.62Å; A319-I322 PolarHBondContact O-N 2.86Å; A319-F323 WeakPolarHBondContact O-CD2 3.41Å; A319-F323 PolarHBondContact O-N 3.45Å; A319-F535 HydrophobicContact CB-CE1 3.9Å; A319-F535 HydrophobicContact CB-CZ 3.58Å; A319-V539 HydrophobicContact CB-CG1 4.21Å; A319-V539 HydrophobicContact CB-CG2 3.95Å
320	T	83.6	Confident	87.6	Confident	16 Å²	16	28.8 Å²	28.8	10%	0.098	14%	0.142	C	C	.	.	H	α-helix	trans	-59	-44.8	-179.9	-55.5	0	0	0	0	110.2	I316 I322 F323 Y324	I316-T320 VanDerWaalsContact O-CB 3.29Å; I316-T320 WeakPolarHBondContact O-CB 3.42Å; I316-T320 PolarHBondContact O-N 2.93Å; I316-T320 PolarHBondContact O-OG1 3.1Å; T320-I322 PolarHBondContact O-N 2.88Å; T320-F323 PolarHBondContact O-N 3.2Å; T320-Y324 HydrophobicContact CG2-CD2 3.49Å; T320-Y324 VanDerWaalsContact CG2-CD2 3.49Å; T320-Y324 HydrophobicContact CG2-CE2 3.58Å; T320-Y324 WeakPolarHBondContact O-CB 3.45Å; T320-Y324 WeakPolarHBondContact O-CD2 3.14Å; T320-Y324 PolarHBondContact O-N 3.16Å
321	Q	90.6	Very high	87.7	Confident	0 Å²	0	22.2 Å²	22.2	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-60.9	-40.7	178.2	-177.4	59.9	28.1	0	0	112.7	F90 L93 Y106 D317 A319 S325	F90-Q321 HydrophobicContact CD2-CG 4.2Å; L93-Q321 HydrophobicContact CD1-CB 3.8Å; L93-Q321 HydrophobicContact CD1-CG 4Å; Y106-Q321 HydrophobicContact CD2-CG 4.49Å; Y106-Q321 HydrophobicContact CE2-CG 3.98Å; D317-Q321 VanDerWaalsContact O-CB 3.22Å; D317-Q321 WeakPolarHBondContact O-CB 3.34Å; D317-Q321 PolarHBondContact O-N 2.51Å; A319-Q321 VanDerWaalsContact C-N 3.31Å; A319-Q321 PolarHBondContact O-N 2.62Å; Q321-S325 WeakPolarHBondContact O-CB 3.43Å; Q321-S325 PolarHBondContact O-N 3.31Å
322	I	91.1	Very high	88	Confident	0 Å²	0	18.4 Å²	18.4	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-64.1	-44.7	178.1	-74.7	-70.3	0	0	0	111.4	Y106 F109 L110 A318 A319 T320 S325 L326	Y106-I322 HydrophobicContact CD1-CD1 4.22Å; Y106-I322 HydrophobicContact CD2-CD1 3.6Å; Y106-I322 HydrophobicContact CD2-CG1 3.74Å; Y106-I322 HydrophobicContact CE1-CD1 3.89Å; Y106-I322 HydrophobicContact CE2-CD1 3.2Å; Y106-I322 HydrophobicContact CE2-CG1 3.69Å; Y106-I322 HydrophobicContact CG-CD1 4.1Å; Y106-I322 HydrophobicContact CG-CG1 4.43Å; F109-I322 HydrophobicContact CB-CG1 4.14Å; L110-I322 HydrophobicContact CB-CD1 3.84Å; L110-I322 HydrophobicContact CD1-CD1 4.26Å; A318-I322 WeakPolarHBondContact O-CG1 3.24Å; A318-I322 PolarHBondContact O-N 2.95Å; A318-I322 VanDerWaalsContact O-N 3.11Å; A319-I322 PolarHBondContact O-N 2.86Å; T320-I322 PolarHBondContact O-N 2.88Å; I322-S325 PolarHBondContact O-N 2.7Å; I322-L326 HydrophobicContact CG2-CD1 3.95Å; I322-L326 WeakPolarHBondContact O-CB 3.26Å; I322-L326 PolarHBondContact O-N 3.04Å
323	F	85.5	Confident	88.5	Confident	2 Å²	2	14.6 Å²	14.6	1%	0.009	7%	0.067	C	C	.	.	H	α-helix	trans	-67.8	-44.7	179.9	-76.1	-68	0	0	0	112.6	A113 L117 A319 T320 G327 A328 L489 V492 F535 L536	A113-F323 HydrophobicContact CB-CZ 3.95Å; L117-F323 HydrophobicContact CD1-CE1 3.52Å; L117-F323 HydrophobicContact CD1-CZ 3.75Å; A319-F323 WeakPolarHBondContact O-CD2 3.41Å; A319-F323 PolarHBondContact O-N 3.45Å; T320-F323 PolarHBondContact O-N 3.2Å; F323-G327 PolarHBondContact O-N 2.94Å; F323-A328 HydrophobicContact CD1-CB 4.44Å; F323-L489 HydrophobicContact CB-CD2 4.07Å; F323-L489 HydrophobicContact CD2-CD2 3.44Å; F323-L489 VanDerWaalsContact CD2-CD2 3.44Å; F323-L489 HydrophobicContact CE2-CD2 4.09Å; F323-L489 HydrophobicContact CG-CD2 3.81Å; F323-V492 HydrophobicContact CE1-CG1 4.24Å; F323-F535 HydrophobicContact CE2-CE1 4.4Å; F323-L536 HydrophobicContact CD2-CD2 4.21Å; F323-L536 HydrophobicContact CE1-CD2 4.09Å; F323-L536 HydrophobicContact CE2-CD2 3.43Å; F323-L536 VanDerWaalsContact CE2-CD2 3.43Å; F323-L536 HydrophobicContact CE2-CG 4.38Å; F323-L536 HydrophobicContact CZ-CD1 4.31Å; F323-L536 HydrophobicContact CZ-CD2 3.36Å; F323-L536 HydrophobicContact CZ-CG 3.98Å
324	Y	82.8	Confident	89	Confident	31 Å²	31	9.4 Å²	9.4	12%	0.122	4%	0.043	C	C	.	.	H	α-helix	trans	-64	-40.8	175.6	-90.4	-81.7	0	0	0	112.4	T320 F330 A484 G485 I488	T320-Y324 HydrophobicContact CG2-CD2 3.49Å; T320-Y324 VanDerWaalsContact CG2-CD2 3.49Å; T320-Y324 HydrophobicContact CG2-CE2 3.58Å; T320-Y324 WeakPolarHBondContact O-CB 3.45Å; T320-Y324 WeakPolarHBondContact O-CD2 3.14Å; T320-Y324 PolarHBondContact O-N 3.16Å; Y324-F330 HydrophobicContact CD1-CZ 4.45Å; Y324-F330 HydrophobicContact CE1-CZ 4.5Å; Y324-A484 HydrophobicContact CE1-CB 3.78Å; Y324-A484 VanDerWaalsContact OH-C 3.24Å; Y324-A484 VanDerWaalsContact OH-CB 3.25Å; Y324-A484 WeakPolarHBondContact OH-CB 3.49Å; Y324-G485 WeakPolarHBondContact OH-CA 3.37Å; Y324-G485 PolarHBondContact OH-N 3.18Å; Y324-I488 HydrophobicContact CE1-CD1 4.21Å
325	S	91.1	Very high	89.2	Confident	1 Å²	1	9.3 Å²	9.3	1%	0.007	4%	0.042	C	C	.	.	H	α-helix	trans	-75	-40.3	-177.3	-178.2	0	0	0	0	112.9	A81 N86 Q321 I322 G327 N357	A81-S325 CarbonylContact C-O 3.49Å; N86-S325 PolarHBondContact ND2-OG 3.24Å; Q321-S325 WeakPolarHBondContact O-CB 3.43Å; Q321-S325 PolarHBondContact O-N 3.31Å; I322-S325 PolarHBondContact O-N 2.7Å; S325-G327 VanDerWaalsContact C-N 3.26Å; S325-G327 PolarHBondContact O-N 2.76Å; S325-N357 PolarHBondContact OG-ND2 3.39Å; S325-N357 PolarHBondContact OG-OD1 3.1Å; S325-N357 VanDerWaalsContact OG-OD1 3.14Å
326	L	91	Very high	89.6	Confident	0 Å²	0	5.7 Å²	5.7	0%	0	3%	0.029	C	C	.	.	H	α-helix	trans	-75.4	-20.4	175.2	-70.3	174.1	0	0	0	112.4	L110 F118 I322 A328 N357	L110-L326 HydrophobicContact CD1-CD1 3.92Å; F118-L326 HydrophobicContact CD2-CB 3.93Å; F118-L326 HydrophobicContact CD2-CD2 4.35Å; F118-L326 HydrophobicContact CE2-CB 4.41Å; F118-L326 VanDerWaalsContact CE2-O 3.28Å; F118-L326 WeakPolarHBondContact CE2-O 3.17Å; I322-L326 HydrophobicContact CG2-CD1 3.95Å; I322-L326 WeakPolarHBondContact O-CB 3.26Å; I322-L326 PolarHBondContact O-N 3.04Å; L326-A328 PolarHBondContact O-N 3.37Å; L326-N357 HydrophobicContact CD2-CB 4.18Å; L326-N357 WeakPolarHBondContact CD2-ND2 3.49Å
327	G	86.5	Confident	90.1	Very high	3 Å²	3	4.7 Å²	4.7	3%	0.031	2%	0.023	C	C	.	.	T	Hydrogen-bonded Turn	trans	68.6	22.2	-177.6	0	0	0	0	0	113.9	F323 S325	F323-G327 PolarHBondContact O-N 2.94Å; S325-G327 VanDerWaalsContact C-N 3.26Å; S325-G327 PolarHBondContact O-N 2.76Å
328	A	88.1	Confident	90.5	Very high	0 Å²	0	3.6 Å²	3.6	0%	0	2%	0.018	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.6	133.7	169.6	0	0	0	0	0	109.5	F323 L326 L333	F323-A328 HydrophobicContact CD1-CB 4.44Å; L326-A328 PolarHBondContact O-N 3.37Å; A328-L333 HydrophobicContact CB-CD1 4.48Å
329	G	86.1	Confident	90.7	Very high	0 Å²	0	4.1 Å²	4.1	0%	0	2%	0.019	C	C	.	.	T	Hydrogen-bonded Turn	trans	96.2	0.3	-177.6	0	0	0	0	0	115.3	E121 V149	E121-G329 WeakPolarHBondContact OE1-CA 3.31Å; E121-G329 PolarHBondContact OE1-N 3.2Å; V149-G329 VanDerWaalsContact CG1-O 3.28Å; V149-G329 WeakPolarHBondContact CG1-O 3.11Å; V149-G329 WeakPolarHBondContact CG2-O 3.36Å
330	F	87.7	Confident	91.2	Very high	17 Å²	17	4.4 Å²	4.4	8%	0.075	2%	0.021	C	C	.	.	S	Bend	trans	-93.8	-6	173.6	-74	-83.2	0	0	0	113.1	F80 V149 I152 V156 Y324 V332 I488	F80-F330 HydrophobicContact CZ-CB 4.14Å; F80-F330 HydrophobicContact CZ-CD2 4.36Å; F80-F330 HydrophobicContact CZ-CG 4.46Å; V149-F330 WeakPolarHBondContact CG1-O 3.07Å; I152-F330 HydrophobicContact CG2-CD1 4.12Å; I152-F330 HydrophobicContact CG2-CE1 3.9Å; V156-F330 HydrophobicContact CB-CE1 4.39Å; V156-F330 HydrophobicContact CG2-CE1 3.76Å; V156-F330 HydrophobicContact CG2-CZ 4.38Å; Y324-F330 HydrophobicContact CD1-CZ 4.45Å; Y324-F330 HydrophobicContact CE1-CZ 4.5Å; F330-V332 HydrophobicContact CB-CG2 3.83Å; F330-V332 PolarHBondContact O-N 3.02Å; F330-I488 HydrophobicContact CD1-CD1 4.35Å; F330-I488 HydrophobicContact CD2-CD1 4.28Å; F330-I488 HydrophobicContact CE1-CD1 3.56Å; F330-I488 HydrophobicContact CE1-CG1 4.4Å; F330-I488 HydrophobicContact CE2-CD1 3.5Å; F330-I488 HydrophobicContact CZ-CD1 3.1Å; F330-I488 HydrophobicContact CZ-CG1 4.27Å
331	G	92.1	Very high	91.6	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	5%	0.045	C	C	.	.	S	Bend	trans	69.8	2.2	179.6	0	0	0	0	0	113.5	I334 A335	G331-I334 PolarHBondContact O-N 3.22Å; G331-A335 WeakPolarHBondContact O-CB 3.33Å; G331-A335 PolarHBondContact O-N 2.84Å
332	V	95.5	Very high	91.7	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-66	-42.3	174.6	-178.9	0	0	0	0	110.2	F80 F330 I334 A335 F336 G429 A433	F80-V332 HydrophobicContact CB-CG1 4.44Å; F80-V332 HydrophobicContact CD1-CB 4.13Å; F80-V332 HydrophobicContact CD1-CG1 3.76Å; F80-V332 HydrophobicContact CD2-CB 4.32Å; F80-V332 HydrophobicContact CD2-CG1 3.79Å; F80-V332 HydrophobicContact CD2-CG2 4.25Å; F80-V332 HydrophobicContact CE1-CB 3.72Å; F80-V332 HydrophobicContact CE1-CG1 3.89Å; F80-V332 HydrophobicContact CE1-CG2 4.22Å; F80-V332 HydrophobicContact CE2-CB 3.96Å; F80-V332 HydrophobicContact CE2-CG1 3.96Å; F80-V332 HydrophobicContact CE2-CG2 3.62Å; F80-V332 HydrophobicContact CG-CB 4.41Å; F80-V332 HydrophobicContact CG-CG1 3.7Å; F80-V332 HydrophobicContact CZ-CB 3.64Å; F80-V332 HydrophobicContact CZ-CG1 4Å; F80-V332 HydrophobicContact CZ-CG2 3.59Å; F330-V332 HydrophobicContact CB-CG2 3.83Å; F330-V332 PolarHBondContact O-N 3.02Å; V332-I334 PolarHBondContact O-N 3.12Å; V332-A335 PolarHBondContact O-N 3.07Å; V332-F336 HydrophobicContact CG1-CD2 3.8Å; V332-F336 HydrophobicContact CG1-CE1 4.37Å; V332-F336 HydrophobicContact CG1-CE2 3.6Å; V332-F336 HydrophobicContact CG1-CG 4.29Å; V332-F336 HydrophobicContact CG1-CZ 3.93Å; V332-F336 WeakPolarHBondContact O-CB 3.41Å; V332-F336 WeakPolarHBondContact O-CG 3.36Å; V332-F336 PolarHBondContact O-N 2.81Å; V332-G429 WeakPolarHBondContact CG2-O 3.32Å; V332-A433 HydrophobicContact CB-CB 4.33Å; V332-A433 HydrophobicContact CG2-CB 3.68Å
333	L	95.9	Very high	91.8	Very high	0 Å²	0	20.1 Å²	20.1	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-64.5	-41.9	177.5	-56.5	177.1	0	0	0	111.1	V77 F80 F118 E121 L122 A328 S337	V77-L333 HydrophobicContact CG1-CD2 3.76Å; F80-L333 HydrophobicContact CD1-CD2 4.24Å; F80-L333 HydrophobicContact CE1-CD2 4.3Å; F118-L333 HydrophobicContact CB-CD1 4.48Å; F118-L333 HydrophobicContact CD2-CD1 3.22Å; F118-L333 HydrophobicContact CD2-CD2 4.19Å; F118-L333 HydrophobicContact CD2-CG 4.33Å; F118-L333 HydrophobicContact CE2-CD1 3.41Å; F118-L333 VanDerWaalsContact CE2-CD1 3.41Å; F118-L333 HydrophobicContact CE2-CD2 3.45Å; F118-L333 VanDerWaalsContact CE2-CD2 3.45Å; F118-L333 HydrophobicContact CE2-CG 4.06Å; F118-L333 HydrophobicContact CG-CD1 3.85Å; F118-L333 HydrophobicContact CZ-CD1 4.15Å; F118-L333 HydrophobicContact CZ-CD2 3.66Å; E121-L333 HydrophobicContact CB-CB 3.9Å; E121-L333 HydrophobicContact CB-CD1 4.23Å; L122-L333 HydrophobicContact CD2-CB 3.93Å; L122-L333 HydrophobicContact CD2-CD2 4.3Å; L122-L333 HydrophobicContact CG-CB 4.35Å; A328-L333 HydrophobicContact CB-CD1 4.48Å; L333-S337 WeakPolarHBondContact O-CB 3.37Å; L333-S337 PolarHBondContact O-N 3.03Å; L333-S337 PolarHBondContact O-OG 3.1Å
334	I	96	Very high	92.2	Very high	2 Å²	2	21 Å²	21	1%	0.01	10%	0.099	C	C	.	.	H	α-helix	trans	-60.4	-49	173.3	-56.7	176.8	0	0	0	109.9	E121 L124 V135 G331 V332 S337 S338	E121-I334 HydrophobicContact CB-CG1 3.98Å; E121-I334 HydrophobicContact CG-CD1 4.2Å; E121-I334 HydrophobicContact CG-CG1 3.93Å; L124-I334 HydrophobicContact CD2-CD1 4.35Å; V135-I334 HydrophobicContact CB-CG2 4.28Å; V135-I334 HydrophobicContact CG1-CD1 4.46Å; V135-I334 HydrophobicContact CG1-CG2 4.29Å; V135-I334 HydrophobicContact CG2-CG2 4.31Å; G331-I334 PolarHBondContact O-N 3.22Å; V332-I334 PolarHBondContact O-N 3.12Å; I334-S337 PolarHBondContact O-OG 3.25Å; I334-S338 WeakPolarHBondContact O-CB 3.29Å; I334-S338 PolarHBondContact O-N 3.11Å
335	A	94.8	Very high	92.7	Very high	0 Å²	0	22.3 Å²	22.3	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-62.2	-49.4	179.8	0	0	0	0	0	112.3	G331 V332 S338 Y339 A433 T436	G331-A335 WeakPolarHBondContact O-CB 3.33Å; G331-A335 PolarHBondContact O-N 2.84Å; V332-A335 PolarHBondContact O-N 3.07Å; A335-S338 WeakPolarHBondContact O-CB 3.25Å; A335-S338 PolarHBondContact O-N 3.38Å; A335-S338 PolarHBondContact O-OG 3.08Å; A335-Y339 WeakPolarHBondContact O-CD2 3.29Å; A335-Y339 WeakPolarHBondContact O-CE2 3.26Å; A335-A433 HydrophobicContact CB-CB 4.42Å; A335-T436 HydrophobicContact CB-CG2 4.13Å
336	F	95.4	Very high	92.9	Very high	4 Å²	4	22.3 Å²	22.3	2%	0.018	11%	0.108	C	C	.	.	H	α-helix	trans	-65.2	-43.3	179.8	-74.7	-11.6	0	0	0	112.9	W67 F73 S76 V77 F80 V332 S338 Y339 G429 E432	W67-F336 HydrophobicContact CH2-CD1 4.21Å; W67-F336 HydrophobicContact CH2-CE1 4.4Å; W67-F336 HydrophobicContact CZ2-CB 4.08Å; W67-F336 AromaticContact CZ2-CD1 3.93Å; W67-F336 HydrophobicContact CZ2-CD1 3.93Å; W67-F336 HydrophobicContact CZ2-CG 4.08Å; W67-F336 PolarHBondContact NE1-O 3.32Å; F73-F336 HydrophobicContact CD2-CB 4.36Å; F73-F336 HydrophobicContact CE2-CB 4.11Å; S76-F336 WeakPolarHBondContact O-CE2 3.45Å; V77-F336 HydrophobicContact CG2-CB 4.39Å; V77-F336 HydrophobicContact CG2-CD2 4.03Å; F80-F336 HydrophobicContact CB-CE2 4.06Å; V332-F336 HydrophobicContact CG1-CD2 3.8Å; V332-F336 HydrophobicContact CG1-CE1 4.37Å; V332-F336 HydrophobicContact CG1-CE2 3.6Å; V332-F336 HydrophobicContact CG1-CG 4.29Å; V332-F336 HydrophobicContact CG1-CZ 3.93Å; V332-F336 WeakPolarHBondContact O-CB 3.41Å; V332-F336 WeakPolarHBondContact O-CG 3.36Å; V332-F336 PolarHBondContact O-N 2.81Å; F336-S338 VanDerWaalsContact C-N 3.3Å; F336-S338 PolarHBondContact O-N 2.98Å; F336-Y339 PolarHBondContact O-N 2.96Å; F336-G429 VanDerWaalsContact CZ-CA 3.49Å; F336-E432 HydrophobicContact CD1-CG 4.32Å; F336-E432 HydrophobicContact CE1-CB 4.06Å; F336-E432 HydrophobicContact CE1-CG 3.9Å
337	S	95.8	Very high	93.1	Very high	0 Å²	0	26 Å²	26	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-69.7	-26.6	178.6	62.6	0	0	0	0	112.8	L122 G125 Q126 L333 I334 Y339 N340	L122-S337 VanDerWaalsContact O-CB 3.24Å; L122-S337 WeakPolarHBondContact O-CB 3.46Å; L122-S337 PolarHBondContact O-OG 3.27Å; G125-S337 VanDerWaalsContact CA-OG 3.28Å; G125-S337 WeakPolarHBondContact CA-OG 3.49Å; Q126-S337 WeakPolarHBondContact CA-O 3.43Å; Q126-S337 PolarHBondContact N-OG 3.25Å; L333-S337 WeakPolarHBondContact O-CB 3.37Å; L333-S337 PolarHBondContact O-N 3.03Å; L333-S337 PolarHBondContact O-OG 3.1Å; I334-S337 PolarHBondContact O-OG 3.25Å; S337-Y339 PolarHBondContact O-N 2.97Å; S337-Y339 VanDerWaalsContact O-N 3.11Å; S337-N340 VanDerWaalsContact O-CB 3.23Å; S337-N340 WeakPolarHBondContact O-CB 3.35Å; S337-N340 PolarHBondContact O-N 3.24Å
338	S	95.7	Very high	93.5	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-58.5	-25.3	174	79.3	0	0	0	0	113.6	R64 G125 E130 I334 A335 F336	R64-S338 VanDerWaalsContact CD-O 3.26Å; R64-S338 WeakPolarHBondContact CD-O 3.43Å; R64-S338 PolarHBondContact NE-O 2.95Å; R64-S338 PolarHBondContact NE-OG 3.31Å; R64-S338 VanDerWaalsContact NE-OG 3.13Å; R64-S338 PolarHBondContact NH2-OG 3.32Å; G125-S338 VanDerWaalsContact O-CA 3.3Å; G125-S338 WeakPolarHBondContact O-CA 3.22Å; E130-S338 WeakPolarHBondContact O-CB 3.17Å; I334-S338 WeakPolarHBondContact O-CB 3.29Å; I334-S338 PolarHBondContact O-N 3.11Å; A335-S338 WeakPolarHBondContact O-CB 3.25Å; A335-S338 PolarHBondContact O-N 3.38Å; A335-S338 PolarHBondContact O-OG 3.08Å; F336-S338 VanDerWaalsContact C-N 3.3Å; F336-S338 PolarHBondContact O-N 2.98Å
339	Y	94.5	Very high	93.8	Very high	10 Å²	10	34 Å²	34	4%	0.039	15%	0.152	C	C	.	.	T	Hydrogen-bonded Turn	trans	-90.3	-1.1	177.3	-61.8	-65.1	0	0	0	113.2	R64 E65 T66 W67 V263 A335 F336 S337 T436 R449	R64-Y339 HydrophobicContact CG-CD1 3.98Å; R64-Y339 HydrophobicContact CG-CE1 4.06Å; E65-Y339 VanDerWaalsContact O-CD1 3.32Å; E65-Y339 WeakPolarHBondContact O-CD1 3.45Å; T66-Y339 VanDerWaalsContact CA-O 3.27Å; T66-Y339 WeakPolarHBondContact CA-O 3.46Å; T66-Y339 WeakPolarHBondContact CB-O 3.14Å; W67-Y339 PolarHBondContact N-O 3.02Å; V263-Y339 HydrophobicContact CB-CD2 4.49Å; V263-Y339 HydrophobicContact CG1-CD1 4.5Å; V263-Y339 HydrophobicContact CG1-CD2 3.32Å; V263-Y339 HydrophobicContact CG1-CE2 3.62Å; V263-Y339 HydrophobicContact CG1-CG 3.81Å; V263-Y339 HydrophobicContact CG2-CD1 4.24Å; V263-Y339 HydrophobicContact CG2-CD2 4.45Å; V263-Y339 HydrophobicContact CG2-CG 4.11Å; A335-Y339 WeakPolarHBondContact O-CD2 3.29Å; A335-Y339 WeakPolarHBondContact O-CE2 3.26Å; F336-Y339 PolarHBondContact O-N 2.96Å; S337-Y339 PolarHBondContact O-N 2.97Å; S337-Y339 VanDerWaalsContact O-N 3.11Å; Y339-T436 HydrophobicContact CE2-CG2 4.09Å; Y339-T436 WeakPolarHBondContact OH-CG2 3.28Å; Y339-T436 PolarHBondContact OH-OG1 3.43Å; Y339-R449 PolarHBondContact OH-NH1 3.25Å; Y339-R449 VanDerWaalsContact OH-NH1 3.12Å
340	N	95.2	Very high	94.3	Very high	7 Å²	7	34.1 Å²	34.1	4%	0.037	15%	0.153	C	C	.	.	S	Bend	trans	-71.4	163.7	174.5	-74	-14.4	0	0	0	111.8	W67 F73 Q126 R129 S337 N344	W67-N340 PolarHBondContact NE1-OD1 3.42Å; F73-N340 WeakPolarHBondContact CD2-OD1 3.48Å; F73-N340 VanDerWaalsContact CE1-ND2 3.31Å; F73-N340 WeakPolarHBondContact CE1-ND2 3.18Å; F73-N340 WeakPolarHBondContact CE2-ND2 3.48Å; F73-N340 WeakPolarHBondContact CG-OD1 3.22Å; F73-N340 WeakPolarHBondContact CZ-ND2 3.26Å; Q126-N340 HydrophobicContact CG-CB 3.99Å; Q126-N340 PolarHBondContact OE1-ND2 3.41Å; R129-N340 PolarHBondContact NH1-O 2.87Å; S337-N340 VanDerWaalsContact O-CB 3.23Å; S337-N340 WeakPolarHBondContact O-CB 3.35Å; S337-N340 PolarHBondContact O-N 3.24Å; N340-N344 HydrophobicContact CB-CB 4.41Å
341	K	93.2	Very high	94.6	Very high	139 Å²	139	36.7 Å²	36.7	60%	0.604	17%	0.167	S	C	*	.			trans	-71.3	145.7	165.7	-63	-178.7	-178.8	-178.9	0	109.1	N343 N344	K341-N343 VanDerWaalsContact C-N 3.26Å; K341-N343 PolarHBondContact O-N 3.46Å; K341-N344 VanDerWaalsContact O-CB 3.3Å; K341-N344 WeakPolarHBondContact O-CB 3.49Å; K341-N344 PolarHBondContact O-N 2.91Å
342	F	92.3	Very high	94.8	Very high	85 Å²	85	40.1 Å²	40.1	37%	0.373	19%	0.185	S	C	.	.	T	Hydrogen-bonded Turn	trans	-57.2	-38.4	-175.9	-174.8	-98.9	0	0	0	113.1	Q126 Y127 N344 M515	Q126-F342 PolarHBondContact NE2-O 3.25Å; Q126-F342 VanDerWaalsContact NE2-O 3.16Å; Y127-F342 AromaticContact CD2-CE2 3.62Å; Y127-F342 HydrophobicContact CD2-CE2 3.62Å; Y127-F342 AromaticContact CD2-CZ 3.86Å; Y127-F342 HydrophobicContact CD2-CZ 3.86Å; Y127-F342 AromaticContact CE2-CE2 3.91Å; Y127-F342 HydrophobicContact CE2-CE2 3.91Å; Y127-F342 AromaticContact CE2-CZ 3.81Å; Y127-F342 HydrophobicContact CE2-CZ 3.81Å; F342-N344 VanDerWaalsContact C-N 3.34Å; F342-N344 PolarHBondContact O-N 3.49Å; F342-M515 HydrophobicContact CD1-CG 4.38Å; F342-M515 HydrophobicContact CD2-CG 4.25Å; F342-M515 HydrophobicContact CE1-CG 3.98Å; F342-M515 HydrophobicContact CE2-CG 3.84Å; F342-M515 HydrophobicContact CZ-CG 3.69Å; F342-M515 WeakPolarHBondContact O-CB 3.5Å
343	N	92.2	Very high	94.8	Very high	121 Å²	121	40.2 Å²	40.2	65%	0.647	19%	0.185	S	C	*	.	T	Hydrogen-bonded Turn	trans	-90.6	14.2	-179.6	67	-14	0	0	0	114.5	K341 M515	K341-N343 VanDerWaalsContact C-N 3.26Å; K341-N343 PolarHBondContact O-N 3.46Å; N343-M515 WeakPolarHBondContact CA-O 3.32Å
344	N	93.8	Very high	94.8	Very high	22 Å²	22	40.2 Å²	40.2	12%	0.118	19%	0.185	C	C	.	.			trans	-70.6	139.9	177	177.6	60.9	0	0	0	110.5	K70 Q126 N340 K341 F342 C346 D349	K70-N344 WeakPolarHBondContact CD-OD1 3.37Å; K70-N344 WeakPolarHBondContact CE-OD1 3.01Å; K70-N344 PolarHBondContact NZ-OD1 3.05Å; Q126-N344 PolarHBondContact NE2-O 3.27Å; Q126-N344 PolarHBondContact OE1-ND2 2.88Å; N340-N344 HydrophobicContact CB-CB 4.41Å; K341-N344 VanDerWaalsContact O-CB 3.3Å; K341-N344 WeakPolarHBondContact O-CB 3.49Å; K341-N344 PolarHBondContact O-N 2.91Å; F342-N344 VanDerWaalsContact C-N 3.34Å; F342-N344 PolarHBondContact O-N 3.49Å; N344-C346 VanDerWaalsContact C-N 3.34Å; N344-C346 PolarHBondContact O-N 2.99Å; N344-D349 PolarHBondContact ND2-OD2 3.01Å
345	N	94.8	Very high	94.8	Very high	58 Å²	58	43.2 Å²	43.2	31%	0.31	20%	0.204	S	C	.	.			trans	-77	84.5	178.4	-172.4	-24.9	0	0	0	110.7	Y347 R348 D349	N345-Y347 VanDerWaalsContact C-N 3.27Å; N345-Y347 PolarHBondContact O-N 3.03Å; N345-Y347 WeakPolarHBondContact OD1-CB 3.46Å; N345-Y347 PolarHBondContact OD1-N 3.18Å; N345-R348 PolarHBondContact OD1-N 3.23Å; N345-D349 PolarHBondContact O-N 3.29Å
346	C	94.4	Very high	94.8	Very high	0 Å²	0	45 Å²	45	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-69	-23.5	178.6	60.6	0	0	0	0	112.8	N344 D349 A350	N344-C346 VanDerWaalsContact C-N 3.34Å; N344-C346 PolarHBondContact O-N 2.99Å; C346-D349 PolarHBondContact O-N 3.34Å; C346-A350 VanDerWaalsContact O-CB 3.28Å; C346-A350 WeakPolarHBondContact O-CB 3.34Å; C346-A350 PolarHBondContact O-N 3.08Å
347	Y	94.8	Very high	94.8	Very high	77 Å²	77	44.9 Å²	44.9	30%	0.302	21%	0.214	S	C	.	.	H	α-helix	trans	-63.2	-48.6	175.1	170.3	-103.1	0	0	0	112.2	Y119 N345 D349 A350 L351 F518 W524	Y119-Y347 HydrophobicContact CD1-CD2 4.38Å; Y119-Y347 AromaticContact CE1-CD2 3.97Å; Y119-Y347 HydrophobicContact CE1-CD2 3.97Å; Y119-Y347 HydrophobicContact CE2-CD2 4.33Å; Y119-Y347 AromaticContact CZ-CD2 3.95Å; N345-Y347 VanDerWaalsContact C-N 3.27Å; N345-Y347 PolarHBondContact O-N 3.03Å; N345-Y347 WeakPolarHBondContact OD1-CB 3.46Å; N345-Y347 PolarHBondContact OD1-N 3.18Å; Y347-D349 VanDerWaalsContact C-N 3.3Å; Y347-D349 PolarHBondContact O-N 3.13Å; Y347-A350 PolarHBondContact O-N 3.2Å; Y347-L351 PolarHBondContact O-N 2.99Å; Y347-L351 VanDerWaalsContact O-N 3.08Å; Y347-F518 HydrophobicContact CD1-CZ 4.29Å; Y347-F518 HydrophobicContact CG-CZ 4.36Å; Y347-W524 HydrophobicContact CD2-CZ2 4.45Å; Y347-W524 AromaticContact CE2-CE2 3.73Å; Y347-W524 AromaticContact CE2-CZ2 3.57Å; Y347-W524 HydrophobicContact CE2-CZ2 3.57Å; Y347-W524 AromaticContact CE2-NE1 3.63Å
348	R	94.4	Very high	94.7	Very high	170 Å²	170	45.6 Å²	45.6	64%	0.642	22%	0.219	S	C	*	.	H	α-helix	trans	-63.8	-39.5	176	-176.4	177.8	176.8	-176.3	-0.5	111.3	N345 A350 L352	N345-R348 PolarHBondContact OD1-N 3.23Å; R348-A350 VanDerWaalsContact C-N 3.35Å; R348-L352 VanDerWaalsContact O-CB 3.23Å; R348-L352 WeakPolarHBondContact O-CB 3.48Å; R348-L352 PolarHBondContact O-N 3.49Å
349	D	95.8	Very high	94.7	Very high	3 Å²	3	49.7 Å²	49.7	2%	0.016	24%	0.244	C	C	.	.	H	α-helix	trans	-67.2	-38.5	-179.4	-59.7	-15.9	0	0	0	110.9	K70 F73 N344 N345 C346 Y347 T353	K70-D349 WeakPolarHBondContact CE-OD1 3.22Å; K70-D349 WeakPolarHBondContact CE-OD2 3.44Å; K70-D349 VanDerWaalsContact NZ-CG 3.35Å; K70-D349 IonicContact NZ-OD1 3.48Å; K70-D349 PolarHBondContact NZ-OD1 3.37Å; K70-D349 IonicContact NZ-OD2 3.29Å; K70-D349 PolarHBondContact NZ-OD2 3.47Å; K70-D349 VanDerWaalsContact NZ-OD2 3.11Å; F73-D349 HydrophobicContact CE1-CB 3.95Å; N344-D349 PolarHBondContact ND2-OD2 3.01Å; N345-D349 PolarHBondContact O-N 3.29Å; C346-D349 PolarHBondContact O-N 3.34Å; Y347-D349 VanDerWaalsContact C-N 3.3Å; Y347-D349 PolarHBondContact O-N 3.13Å; D349-T353 VanDerWaalsContact O-CB 3.31Å; D349-T353 WeakPolarHBondContact O-CB 3.48Å; D349-T353 PolarHBondContact O-N 3.23Å; D349-T353 PolarHBondContact O-OG1 2.85Å
350	A	95.5	Very high	94.7	Very high	2 Å²	2	49.5 Å²	49.5	2%	0.017	24%	0.244	C	C	.	.	H	α-helix	trans	-63.1	-49.3	174.8	0	0	0	0	0	112.5	F118 Y119 L122 C346 Y347 R348 S354	F118-A350 HydrophobicContact CD1-CB 4.02Å; F118-A350 HydrophobicContact CE1-CB 4.39Å; Y119-A350 HydrophobicContact CD2-CB 3.96Å; Y119-A350 HydrophobicContact CG-CB 4.24Å; L122-A350 HydrophobicContact CD1-CB 3.88Å; C346-A350 VanDerWaalsContact O-CB 3.28Å; C346-A350 WeakPolarHBondContact O-CB 3.34Å; C346-A350 PolarHBondContact O-N 3.08Å; Y347-A350 PolarHBondContact O-N 3.2Å; R348-A350 VanDerWaalsContact C-N 3.35Å; A350-S354 VanDerWaalsContact O-CB 3.31Å; A350-S354 WeakPolarHBondContact O-CB 3.46Å; A350-S354 PolarHBondContact O-N 3.4Å; A350-S354 PolarHBondContact O-OG 3.11Å
351	L	95.8	Very high	94.7	Very high	71 Å²	71	49.2 Å²	49.2	37%	0.372	24%	0.242	S	C	.	.	H	α-helix	trans	-63.2	-49.4	179	179.8	62	0	0	0	111.2	M115 Y347 T353 S354 T355	M115-L351 HydrophobicContact CE-CD1 3.87Å; M115-L351 HydrophobicContact SD-CD1 3.53Å; M115-L351 VanDerWaalsContact SD-CD1 3.53Å; Y347-L351 PolarHBondContact O-N 2.99Å; Y347-L351 VanDerWaalsContact O-N 3.08Å; L351-T353 PolarHBondContact O-N 2.96Å; L351-S354 PolarHBondContact O-N 3.28Å; L351-T355 WeakPolarHBondContact O-CB 3.03Å; L351-T355 PolarHBondContact O-N 2.89Å; L351-T355 PolarHBondContact O-OG1 2.75Å; L351-T355 VanDerWaalsContact O-OG1 3.06Å
352	L	96.1	Very high	94.7	Very high	71 Å²	71	46.1 Å²	46.1	37%	0.372	23%	0.229	S	C	.	.	H	α-helix	trans	-59.7	-48.9	-179.3	178.4	60.7	0	0	0	111.4	L74 R348 T355 V356	L74-L352 HydrophobicContact CD1-CD2 4Å; L74-L352 HydrophobicContact CD1-CG 4.46Å; L74-L352 HydrophobicContact CD2-CD2 3.63Å; L74-L352 HydrophobicContact CG-CD2 4.44Å; R348-L352 VanDerWaalsContact O-CB 3.23Å; R348-L352 WeakPolarHBondContact O-CB 3.48Å; R348-L352 PolarHBondContact O-N 3.49Å; L352-T355 PolarHBondContact O-N 2.91Å; L352-V356 HydrophobicContact CD1-CG2 4.08Å; L352-V356 HydrophobicContact CG-CG2 4.5Å; L352-V356 WeakPolarHBondContact O-CB 3.48Å; L352-V356 VanDerWaalsContact O-CG2 3.26Å; L352-V356 WeakPolarHBondContact O-CG2 3.09Å; L352-V356 PolarHBondContact O-N 3.43Å
353	T	95.7	Very high	94.8	Very high	2 Å²	2	45.1 Å²	45.1	1%	0.012	23%	0.225	C	C	.	.	H	α-helix	trans	-67.2	-41.9	-176.7	-50.1	0	0	0	0	111.6	L74 V77 I78 A81 F118 D349 L351 T355 V356 N357	L74-T353 WeakPolarHBondContact CD1-OG1 3.48Å; V77-T353 HydrophobicContact CB-CG2 4.25Å; V77-T353 HydrophobicContact CG1-CG2 3.62Å; I78-T353 HydrophobicContact CB-CG2 4.47Å; I78-T353 HydrophobicContact CG1-CG2 3.69Å; A81-T353 HydrophobicContact CB-CG2 4.48Å; F118-T353 HydrophobicContact CE1-CG2 4.44Å; F118-T353 HydrophobicContact CZ-CG2 3.89Å; D349-T353 VanDerWaalsContact O-CB 3.31Å; D349-T353 WeakPolarHBondContact O-CB 3.48Å; D349-T353 PolarHBondContact O-N 3.23Å; D349-T353 PolarHBondContact O-OG1 2.85Å; L351-T353 PolarHBondContact O-N 2.96Å; T353-T355 PolarHBondContact O-N 3.17Å; T353-V356 PolarHBondContact O-N 2.88Å; T353-N357 WeakPolarHBondContact O-CB 3.49Å; T353-N357 PolarHBondContact O-N 3.15Å
354	S	95.3	Very high	94.8	Very high	0 Å²	0	39.4 Å²	39.4	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-62.5	-43.1	177.3	-57.2	0	0	0	0	111.8	A350 L351 N357 C358	A350-S354 VanDerWaalsContact O-CB 3.31Å; A350-S354 WeakPolarHBondContact O-CB 3.46Å; A350-S354 PolarHBondContact O-N 3.4Å; A350-S354 PolarHBondContact O-OG 3.11Å; L351-S354 PolarHBondContact O-N 3.28Å; S354-N357 PolarHBondContact O-N 3.37Å; S354-C358 PolarHBondContact O-N 3.46Å; S354-C358 VanDerWaalsContact O-N 3.16Å; S354-C358 PolarHBondContact O-SG 2.96Å
355	T	94.9	Very high	94.8	Very high	66 Å²	66	38.3 Å²	38.3	41%	0.405	19%	0.188	S	C	.	.	H	α-helix	trans	-66.2	-45.2	176.7	-60.5	0	0	0	0	111.7	L351 L352 T353 N357 C358 V359	L351-T355 WeakPolarHBondContact O-CB 3.03Å; L351-T355 PolarHBondContact O-N 2.89Å; L351-T355 PolarHBondContact O-OG1 2.75Å; L351-T355 VanDerWaalsContact O-OG1 3.06Å; L352-T355 PolarHBondContact O-N 2.91Å; T353-T355 PolarHBondContact O-N 3.17Å; T355-N357 VanDerWaalsContact C-N 3.32Å; T355-N357 PolarHBondContact O-N 3.19Å; T355-C358 PolarHBondContact O-N 3.39Å; T355-V359 HydrophobicContact CG2-CG2 4.16Å; T355-V359 WeakPolarHBondContact O-CB 3.22Å; T355-V359 VanDerWaalsContact O-CG2 3.27Å; T355-V359 WeakPolarHBondContact O-CG2 3.32Å; T355-V359 PolarHBondContact O-N 3.17Å
356	V	95.9	Very high	94.8	Very high	37 Å²	37	37.6 Å²	37.6	22%	0.224	18%	0.182	C	C	.	.	H	α-helix	trans	-58.2	-47.1	176.8	168.5	0	0	0	0	110.2	I78 Y278 L352 T353 C358 V359 T360	I78-V356 HydrophobicContact CD1-CG1 4.32Å; I78-V356 HydrophobicContact CG1-CG1 4.43Å; I78-V356 HydrophobicContact CG2-CG1 4Å; Y278-V356 HydrophobicContact CE1-CG1 4.49Å; Y278-V356 VanDerWaalsContact OH-CG1 3.3Å; Y278-V356 WeakPolarHBondContact OH-CG1 3.27Å; L352-V356 HydrophobicContact CD1-CG2 4.08Å; L352-V356 HydrophobicContact CG-CG2 4.5Å; L352-V356 WeakPolarHBondContact O-CB 3.48Å; L352-V356 VanDerWaalsContact O-CG2 3.26Å; L352-V356 WeakPolarHBondContact O-CG2 3.09Å; L352-V356 PolarHBondContact O-N 3.43Å; T353-V356 PolarHBondContact O-N 2.88Å; V356-C358 PolarHBondContact O-N 2.92Å; V356-V359 PolarHBondContact O-N 2.98Å; V356-T360 WeakPolarHBondContact O-CB 3.26Å; V356-T360 PolarHBondContact O-N 3.39Å; V356-T360 PolarHBondContact O-OG1 2.87Å
357	N	95.5	Very high	94.6	Very high	1 Å²	1	37.7 Å²	37.7	1%	0.005	18%	0.183	C	C	.	.	H	α-helix	trans	-55	-50.6	177.9	177.7	50.9	0	0	0	112.8	A81 V82 N86 S325 L326 T353 S354 T355 T360 S361	A81-N357 HydrophobicContact CB-CB 4.33Å; A81-N357 PolarHBondContact O-OD1 3.33Å; A81-N357 VanDerWaalsContact O-OD1 3.04Å; V82-N357 HydrophobicContact CG2-CB 4.45Å; N86-N357 PolarHBondContact ND2-O 3.23Å; N86-N357 PolarHBondContact ND2-OD1 2.96Å; S325-N357 PolarHBondContact OG-ND2 3.39Å; S325-N357 PolarHBondContact OG-OD1 3.1Å; S325-N357 VanDerWaalsContact OG-OD1 3.14Å; L326-N357 HydrophobicContact CD2-CB 4.18Å; L326-N357 WeakPolarHBondContact CD2-ND2 3.49Å; T353-N357 WeakPolarHBondContact O-CB 3.49Å; T353-N357 PolarHBondContact O-N 3.15Å; S354-N357 PolarHBondContact O-N 3.37Å; T355-N357 VanDerWaalsContact C-N 3.32Å; T355-N357 PolarHBondContact O-N 3.19Å; N357-T360 PolarHBondContact O-N 3.43Å; N357-S361 PolarHBondContact O-N 3.03Å; N357-S361 PolarHBondContact O-OG 3.46Å
358	C	93.9	Very high	94.4	Very high	16 Å²	16	34.2 Å²	34.2	11%	0.108	17%	0.17	C	C	.	.	H	α-helix	trans	-67.2	-39	179.8	-67.9	0	0	0	0	112.9	Y106 L110 S354 T355 V356 T360 S361 F362	Y106-C358 HydrophobicContact CE1-CB 4.22Å; Y106-C358 PolarHBondContact OH-SG 2.86Å; Y106-C358 VanDerWaalsContact OH-SG 3.37Å; L110-C358 HydrophobicContact CD2-CB 4.23Å; L110-C358 WeakPolarHBondContact CD2-SG 3.48Å; S354-C358 PolarHBondContact O-N 3.46Å; S354-C358 VanDerWaalsContact O-N 3.16Å; S354-C358 PolarHBondContact O-SG 2.96Å; T355-C358 PolarHBondContact O-N 3.39Å; V356-C358 PolarHBondContact O-N 2.92Å; C358-T360 VanDerWaalsContact C-N 3.33Å; C358-S361 PolarHBondContact O-N 3.2Å; C358-F362 PolarHBondContact O-N 3.44Å
359	V	94.7	Very high	94.3	Very high	85 Å²	85	26.2 Å²	26.2	52%	0.515	14%	0.139	S	C	.	.	H	α-helix	trans	-64.1	-40.6	175.4	169.9	0	0	0	0	110.5	T355 V356 F362 F363	T355-V359 HydrophobicContact CG2-CG2 4.16Å; T355-V359 WeakPolarHBondContact O-CB 3.22Å; T355-V359 VanDerWaalsContact O-CG2 3.27Å; T355-V359 WeakPolarHBondContact O-CG2 3.32Å; T355-V359 PolarHBondContact O-N 3.17Å; V356-V359 PolarHBondContact O-N 2.98Å; V359-F362 PolarHBondContact O-N 3.46Å; V359-F363 VanDerWaalsContact O-CB 3.28Å; V359-F363 WeakPolarHBondContact O-CB 3.3Å; V359-F363 PolarHBondContact O-N 3.26Å
360	T	94.6	Very high	94.1	Very high	7 Å²	7	26 Å²	26	4%	0.043	14%	0.139	C	C	.	.	H	α-helix	trans	-63.1	-43.8	176.5	-55	0	0	0	0	111.7	V82 Y278 L281 V356 N357 C358 F362 F363 S364	V82-T360 HydrophobicContact CG1-CG2 3.6Å; V82-T360 HydrophobicContact CG2-CG2 4.39Å; Y278-T360 HydrophobicContact CE1-CG2 4.05Å; Y278-T360 VanDerWaalsContact CE1-OG1 3.25Å; Y278-T360 WeakPolarHBondContact CE1-OG1 3.22Å; Y278-T360 PolarHBondContact OH-OG1 3.42Å; L281-T360 HydrophobicContact CD1-CG2 4.08Å; V356-T360 WeakPolarHBondContact O-CB 3.26Å; V356-T360 PolarHBondContact O-N 3.39Å; V356-T360 PolarHBondContact O-OG1 2.87Å; N357-T360 PolarHBondContact O-N 3.43Å; C358-T360 VanDerWaalsContact C-N 3.33Å; T360-F362 VanDerWaalsContact C-N 3.34Å; T360-F362 PolarHBondContact O-N 3.03Å; T360-F363 PolarHBondContact O-N 2.65Å; T360-S364 WeakPolarHBondContact O-CB 3.2Å; T360-S364 PolarHBondContact O-N 3.41Å; T360-S364 PolarHBondContact O-OG 2.83Å
361	S	94.6	Very high	93.8	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-58.5	-43.4	173.5	-65.1	0	0	0	0	112.7	N86 F90 N357 C358 S364 G365	N86-S361 PolarHBondContact ND2-OG 2.95Å; F90-S361 VanDerWaalsContact CD1-C 3.46Å; F90-S361 WeakPolarHBondContact CD1-O 3.42Å; F90-S361 VanDerWaalsContact CE1-C 3.46Å; F90-S361 VanDerWaalsContact CE1-O 3.24Å; F90-S361 WeakPolarHBondContact CE1-O 3.34Å; N357-S361 PolarHBondContact O-N 3.03Å; N357-S361 PolarHBondContact O-OG 3.46Å; C358-S361 PolarHBondContact O-N 3.2Å; S361-S364 PolarHBondContact O-OG 3.4Å; S361-G365 PolarHBondContact O-N 2.88Å
362	F	94.2	Very high	93.4	Very high	74 Å²	74	23.4 Å²	23.4	33%	0.325	13%	0.125	S	C	.	.	H	α-helix	trans	-66.4	-43.3	177.5	-174.4	-118.8	0	0	0	111.8	L103 Y301 L302 C358 V359 T360 G365 F366	L103-F362 HydrophobicContact CD1-CD2 4.39Å; L103-F362 HydrophobicContact CD1-CE2 3.88Å; L103-F362 HydrophobicContact CD2-CD2 4.36Å; Y301-F362 HydrophobicContact CE1-CD2 4.41Å; Y301-F362 HydrophobicContact CE1-CE2 4.27Å; Y301-F362 WeakPolarHBondContact OH-CD2 3.36Å; L302-F362 HydrophobicContact CD2-CE2 4.04Å; L302-F362 HydrophobicContact CD2-CZ 4.47Å; C358-F362 PolarHBondContact O-N 3.44Å; V359-F362 PolarHBondContact O-N 3.46Å; T360-F362 VanDerWaalsContact C-N 3.34Å; T360-F362 PolarHBondContact O-N 3.03Å; F362-G365 PolarHBondContact O-N 3.28Å; F362-F366 AromaticContact CD1-CE2 3.91Å; F362-F366 HydrophobicContact CD1-CE2 3.91Å; F362-F366 HydrophobicContact CD2-CE2 4.32Å; F362-F366 AromaticContact CE1-CE2 3.46Å; F362-F366 HydrophobicContact CE1-CE2 3.46Å; F362-F366 VanDerWaalsContact CE1-CE2 3.46Å; F362-F366 HydrophobicContact CE1-CZ 4.06Å; F362-F366 AromaticContact CE2-CE2 3.89Å; F362-F366 HydrophobicContact CE2-CE2 3.89Å; F362-F366 HydrophobicContact CE2-CZ 4.32Å; F362-F366 HydrophobicContact CG-CE2 4.33Å; F362-F366 AromaticContact CZ-CE2 3.44Å; F362-F366 HydrophobicContact CZ-CE2 3.44Å; F362-F366 VanDerWaalsContact CZ-CE2 3.44Å; F362-F366 AromaticContact CZ-CZ 3.73Å; F362-F366 HydrophobicContact CZ-CZ 3.73Å; F362-F366 VanDerWaalsContact O-CD2 3.29Å; F362-F366 WeakPolarHBondContact O-CD2 3.28Å
363	F	94	Very high	93.1	Very high	65 Å²	65	20 Å²	20	29%	0.285	11%	0.107	S	C	.	.	H	α-helix	trans	-68.3	-42.2	-179.8	-171.7	-96.1	0	0	0	112.9	L281 F282 L285 V359 T360 G365 F366 A367	L281-F363 HydrophobicContact CB-CD1 4.27Å; L281-F363 HydrophobicContact CB-CE1 4.12Å; F282-F363 HydrophobicContact CD2-CZ 4.03Å; L285-F363 HydrophobicContact CB-CE1 4.29Å; L285-F363 HydrophobicContact CB-CZ 4.06Å; L285-F363 HydrophobicContact CD2-CD2 4.04Å; L285-F363 HydrophobicContact CD2-CE1 4.04Å; L285-F363 HydrophobicContact CD2-CE2 3.18Å; L285-F363 HydrophobicContact CD2-CZ 3.18Å; L285-F363 HydrophobicContact CG-CZ 4.22Å; V359-F363 VanDerWaalsContact O-CB 3.28Å; V359-F363 WeakPolarHBondContact O-CB 3.3Å; V359-F363 PolarHBondContact O-N 3.26Å; T360-F363 PolarHBondContact O-N 2.65Å; F363-G365 PolarHBondContact O-N 3.49Å; F363-F366 PolarHBondContact O-N 3.28Å; F363-A367 PolarHBondContact O-N 2.74Å
364	S	93.1	Very high	92.8	Very high	0 Å²	0	20.9 Å²	20.9	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-59.6	-34.5	173.7	66.3	0	0	0	0	110.8	N86 T360 S361 F366 A367 I368	N86-S364 PolarHBondContact O-OG 3.48Å; T360-S364 WeakPolarHBondContact O-CB 3.2Å; T360-S364 PolarHBondContact O-N 3.41Å; T360-S364 PolarHBondContact O-OG 2.83Å; S361-S364 PolarHBondContact O-OG 3.4Å; S364-F366 PolarHBondContact O-N 3.47Å; S364-A367 PolarHBondContact O-N 3.37Å; S364-I368 VanDerWaalsContact O-CB 3.26Å; S364-I368 WeakPolarHBondContact O-CB 3.34Å; S364-I368 VanDerWaalsContact O-CG1 3.22Å; S364-I368 WeakPolarHBondContact O-CG1 3.28Å; S364-I368 PolarHBondContact O-N 3.38Å
365	G	93	Very high	92.2	Very high	0 Å²	0	21 Å²	21	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-56.5	-43.9	174.6	0	0	0	0	0	113.7	S361 F362 F363 I368 F369	S361-G365 PolarHBondContact O-N 2.88Å; F362-G365 PolarHBondContact O-N 3.28Å; F363-G365 PolarHBondContact O-N 3.49Å; G365-I368 PolarHBondContact O-N 3.29Å; G365-F369 WeakPolarHBondContact O-CB 3.36Å; G365-F369 WeakPolarHBondContact O-CD2 3.06Å; G365-F369 PolarHBondContact O-N 2.95Å
366	F	94.1	Very high	91.7	Very high	43 Å²	43	17.9 Å²	17.9	19%	0.189	9%	0.092	C	C	.	.	H	α-helix	trans	-66.2	-43.3	174.1	-71.2	-86.6	0	0	0	112.6	L285 I298 Y301 L302 F362 F363 S364 I368 S370	L285-F366 HydrophobicContact CD1-CB 3.51Å; I298-F366 HydrophobicContact CG1-CD1 4.39Å; I298-F366 HydrophobicContact CG2-CD1 4.17Å; I298-F366 HydrophobicContact CG2-CE1 4.06Å; Y301-F366 HydrophobicContact CE1-CD2 4.21Å; Y301-F366 HydrophobicContact CE1-CE2 4.19Å; Y301-F366 HydrophobicContact CE1-CZ 4.49Å; L302-F366 HydrophobicContact CD1-CE1 3.73Å; L302-F366 HydrophobicContact CD1-CZ 3.76Å; F362-F366 AromaticContact CD1-CE2 3.91Å; F362-F366 HydrophobicContact CD1-CE2 3.91Å; F362-F366 HydrophobicContact CD2-CE2 4.32Å; F362-F366 AromaticContact CE1-CE2 3.46Å; F362-F366 HydrophobicContact CE1-CE2 3.46Å; F362-F366 VanDerWaalsContact CE1-CE2 3.46Å; F362-F366 HydrophobicContact CE1-CZ 4.06Å; F362-F366 AromaticContact CE2-CE2 3.89Å; F362-F366 HydrophobicContact CE2-CE2 3.89Å; F362-F366 HydrophobicContact CE2-CZ 4.32Å; F362-F366 HydrophobicContact CG-CE2 4.33Å; F362-F366 AromaticContact CZ-CE2 3.44Å; F362-F366 HydrophobicContact CZ-CE2 3.44Å; F362-F366 VanDerWaalsContact CZ-CE2 3.44Å; F362-F366 AromaticContact CZ-CZ 3.73Å; F362-F366 HydrophobicContact CZ-CZ 3.73Å; F362-F366 VanDerWaalsContact O-CD2 3.29Å; F362-F366 WeakPolarHBondContact O-CD2 3.28Å; F363-F366 PolarHBondContact O-N 3.28Å; S364-F366 PolarHBondContact O-N 3.47Å; F366-I368 VanDerWaalsContact C-N 3.25Å; F366-I368 PolarHBondContact O-N 2.64Å; F366-S370 WeakPolarHBondContact O-CB 3.36Å; F366-S370 PolarHBondContact O-N 2.93Å; F366-S370 PolarHBondContact O-OG 3.37Å
367	A	91.9	Very high	91.2	Very high	2 Å²	2	20.6 Å²	20.6	2%	0.017	10%	0.102	C	C	.	.	H	α-helix	trans	-60.3	-41.7	178.1	0	0	0	0	0	110.6	L285 F363 S364 S370 V371	L285-A367 HydrophobicContact CB-CB 4.23Å; L285-A367 HydrophobicContact CD1-CB 4.44Å; F363-A367 PolarHBondContact O-N 2.74Å; S364-A367 PolarHBondContact O-N 3.37Å; A367-S370 PolarHBondContact O-OG 3.03Å; A367-V371 WeakPolarHBondContact O-CG2 3.36Å
368	I	89.9	Confident	90.5	Very high	3 Å²	3	24.7 Å²	24.7	2%	0.015	12%	0.12	C	C	.	.	H	α-helix	trans	-68.1	-56.4	179.9	-75.4	5.2	0	0	0	111.9	V87 P91 S364 G365 F366 S370 V371 L372 Y398	V87-I368 HydrophobicContact CG1-CD1 3.69Å; V87-I368 HydrophobicContact CG1-CG1 4.14Å; V87-I368 WeakPolarHBondContact O-CG1 3.2Å; P91-I368 HydrophobicContact CB-CB 4.31Å; P91-I368 HydrophobicContact CB-CG2 3.82Å; P91-I368 HydrophobicContact CG-CB 4.39Å; P91-I368 HydrophobicContact CG-CG1 4.26Å; P91-I368 HydrophobicContact CG-CG2 4.34Å; S364-I368 VanDerWaalsContact O-CB 3.26Å; S364-I368 WeakPolarHBondContact O-CB 3.34Å; S364-I368 VanDerWaalsContact O-CG1 3.22Å; S364-I368 WeakPolarHBondContact O-CG1 3.28Å; S364-I368 PolarHBondContact O-N 3.38Å; G365-I368 PolarHBondContact O-N 3.29Å; F366-I368 VanDerWaalsContact C-N 3.25Å; F366-I368 PolarHBondContact O-N 2.64Å; I368-S370 VanDerWaalsContact C-N 3.32Å; I368-S370 PolarHBondContact O-N 3.19Å; I368-V371 PolarHBondContact O-N 2.88Å; I368-L372 HydrophobicContact CG2-CD1 3.93Å; I368-L372 WeakPolarHBondContact O-CG 3.31Å; I368-L372 PolarHBondContact O-N 3.33Å; I368-Y398 WeakPolarHBondContact CA-OH 3.46Å; I368-Y398 WeakPolarHBondContact CB-OH 3.17Å; I368-Y398 HydrophobicContact CD1-CE1 3.96Å; I368-Y398 HydrophobicContact CD1-CE2 4.14Å; I368-Y398 VanDerWaalsContact CD1-CZ 3.44Å; I368-Y398 WeakPolarHBondContact CD1-OH 3.29Å; I368-Y398 HydrophobicContact CG1-CE2 4.3Å; I368-Y398 WeakPolarHBondContact CG1-OH 3.47Å; I368-Y398 WeakPolarHBondContact CG2-OH 3.32Å
369	F	91.4	Very high	89.7	Confident	2 Å²	2	24.6 Å²	24.6	1%	0.009	12%	0.118	C	C	.	.	H	α-helix	trans	-72	-26	-174.4	-87	-93.8	0	0	0	113.4	P91 Y95 G297 Y301 G365 V371 L372 G373 V383	P91-F369 HydrophobicContact CB-CD2 3.94Å; P91-F369 HydrophobicContact CB-CE2 3.57Å; P91-F369 VanDerWaalsContact O-CE2 3.26Å; P91-F369 WeakPolarHBondContact O-CE2 3.38Å; Y95-F369 HydrophobicContact CD1-CE1 4.5Å; Y95-F369 HydrophobicContact CD1-CZ 4.43Å; Y95-F369 AromaticContact CD2-CE1 3.8Å; Y95-F369 HydrophobicContact CD2-CE1 3.8Å; Y95-F369 HydrophobicContact CD2-CZ 4.23Å; Y95-F369 AromaticContact CG-CE1 3.76Å; Y95-F369 HydrophobicContact CG-CE1 3.76Å; Y95-F369 AromaticContact CG-CZ 3.75Å; Y95-F369 HydrophobicContact CG-CZ 3.75Å; G297-F369 VanDerWaalsContact CA-O 3.29Å; G297-F369 WeakPolarHBondContact CA-O 3.42Å; G297-F369 WeakPolarHBondContact O-CD1 3.22Å; Y301-F369 AromaticContact CD2-CD2 3.67Å; Y301-F369 HydrophobicContact CD2-CD2 3.67Å; Y301-F369 AromaticContact CD2-CE2 3.89Å; Y301-F369 HydrophobicContact CD2-CE2 3.89Å; Y301-F369 HydrophobicContact CD2-CG 4.22Å; Y301-F369 HydrophobicContact CE2-CD2 4.45Å; Y301-F369 HydrophobicContact CG-CB 4.28Å; Y301-F369 AromaticContact CG-CD2 3.9Å; Y301-F369 HydrophobicContact CG-CD2 3.9Å; Y301-F369 HydrophobicContact CG-CG 4.03Å; G365-F369 WeakPolarHBondContact O-CB 3.36Å; G365-F369 WeakPolarHBondContact O-CD2 3.06Å; G365-F369 PolarHBondContact O-N 2.95Å; F369-V371 VanDerWaalsContact C-N 3.33Å; F369-V371 PolarHBondContact O-N 2.9Å; F369-L372 HydrophobicContact CD1-CD1 4.25Å; F369-L372 HydrophobicContact CE1-CD1 4.21Å; F369-L372 HydrophobicContact CE2-CD1 4.45Å; F369-L372 HydrophobicContact CG-CD1 4.39Å; F369-L372 HydrophobicContact CZ-CD1 4.27Å; F369-L372 PolarHBondContact O-N 3.29Å; F369-G373 PolarHBondContact O-N 3.37Å; F369-V383 HydrophobicContact CD1-CG1 4.32Å; F369-V383 HydrophobicContact CE1-CG1 4.18Å
370	S	93.2	Very high	88.9	Confident	0 Å²	0	27.8 Å²	27.8	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-63.4	-39.6	172.4	62.7	0	0	0	0	112.2	G288 S294 F366 A367 I368 Y374	G288-S370 WeakPolarHBondContact CA-OG 3.45Å; S294-S370 WeakPolarHBondContact CA-O 3.45Å; F366-S370 WeakPolarHBondContact O-CB 3.36Å; F366-S370 PolarHBondContact O-N 2.93Å; F366-S370 PolarHBondContact O-OG 3.37Å; A367-S370 PolarHBondContact O-OG 3.03Å; I368-S370 VanDerWaalsContact C-N 3.32Å; I368-S370 PolarHBondContact O-N 3.19Å; S370-Y374 PolarHBondContact O-N 2.75Å
371	V	88.8	Confident	88.1	Confident	14 Å²	14	28.5 Å²	28.5	9%	0.085	14%	0.137	C	C	.	.	H	α-helix	trans	-72.3	-40.7	175.5	177.1	0	0	0	0	111.5	A367 I368 F369 G373 Y374 M375 Y398 A401	A367-V371 WeakPolarHBondContact O-CG2 3.36Å; I368-V371 PolarHBondContact O-N 2.88Å; F369-V371 VanDerWaalsContact C-N 3.33Å; F369-V371 PolarHBondContact O-N 2.9Å; V371-G373 VanDerWaalsContact C-N 3.35Å; V371-G373 PolarHBondContact O-N 3.28Å; V371-Y374 WeakPolarHBondContact O-CB 3.47Å; V371-Y374 PolarHBondContact O-N 3.33Å; V371-M375 PolarHBondContact O-N 3.07Å; V371-Y398 HydrophobicContact CB-CE1 4.35Å; V371-Y398 HydrophobicContact CG1-CD1 4.46Å; V371-Y398 HydrophobicContact CG1-CE1 4.32Å; V371-A401 HydrophobicContact CG1-CB 3.29Å
372	L	87.3	Confident	87.4	Confident	3 Å²	3	35.4 Å²	35.4	2%	0.016	16%	0.163	C	C	.	.	H	α-helix	trans	-62.8	-39.1	175.3	-69.8	174.6	0	0	0	112.6	I368 F369 Y374 M375 A376 V386 A387 L393 I397	I368-L372 HydrophobicContact CG2-CD1 3.93Å; I368-L372 WeakPolarHBondContact O-CG 3.31Å; I368-L372 PolarHBondContact O-N 3.33Å; F369-L372 HydrophobicContact CD1-CD1 4.25Å; F369-L372 HydrophobicContact CE1-CD1 4.21Å; F369-L372 HydrophobicContact CE2-CD1 4.45Å; F369-L372 HydrophobicContact CG-CD1 4.39Å; F369-L372 HydrophobicContact CZ-CD1 4.27Å; F369-L372 PolarHBondContact O-N 3.29Å; L372-Y374 VanDerWaalsContact C-N 3.35Å; L372-M375 PolarHBondContact O-N 3.49Å; L372-A376 WeakPolarHBondContact O-CB 3.45Å; L372-A376 PolarHBondContact O-N 3.46Å; L372-V386 HydrophobicContact CD2-CB 4.43Å; L372-V386 HydrophobicContact CD2-CG2 4.21Å; L372-A387 HydrophobicContact CD1-CB 4.38Å; L372-L393 HydrophobicContact CD1-CD1 4.36Å; L372-L393 HydrophobicContact CD2-CD1 4.19Å; L372-I397 HydrophobicContact CD2-CG2 3.35Å
373	G	89.7	Confident	86.8	Confident	0 Å²	0	32.8 Å²	32.8	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-62.6	-42	175.9	0	0	0	0	0	112.3	G293 F369 V371 A376 Q377	G293-G373 CarbonylContact O-C 3.5Å; G293-G373 VanDerWaalsContact O-C 3.28Å; G293-G373 WeakPolarHBondContact O-CA 3.33Å; F369-G373 PolarHBondContact O-N 3.37Å; V371-G373 VanDerWaalsContact C-N 3.35Å; V371-G373 PolarHBondContact O-N 3.28Å; G373-A376 PolarHBondContact O-N 2.97Å; G373-Q377 PolarHBondContact O-N 3.44Å
374	Y	88.1	Confident	85.8	Confident	21 Å²	21	34.1 Å²	34.1	8%	0.082	16%	0.16	C	C	.	.	H	α-helix	trans	-60.9	-44.7	172.6	160.2	-103	0	0	0	112.5	L291 P292 S370 V371 L372 Q377 K378 T404 L405	L291-Y374 HydrophobicContact CB-CD2 3.85Å; L291-Y374 HydrophobicContact CB-CG 3.82Å; L291-Y374 HydrophobicContact CD1-CD1 3.81Å; L291-Y374 HydrophobicContact CD1-CD2 4.44Å; L291-Y374 HydrophobicContact CD1-CE1 4.37Å; L291-Y374 HydrophobicContact CD1-CG 3.83Å; L291-Y374 HydrophobicContact CD2-CD2 4.26Å; L291-Y374 HydrophobicContact CD2-CE2 4.27Å; L291-Y374 HydrophobicContact CD2-CG 4.45Å; L291-Y374 HydrophobicContact CG-CD2 4.4Å; L291-Y374 HydrophobicContact CG-CG 4.24Å; P292-Y374 HydrophobicContact CG-CD2 3.84Å; P292-Y374 HydrophobicContact CG-CE2 4.02Å; P292-Y374 VanDerWaalsContact O-CA 3.25Å; P292-Y374 WeakPolarHBondContact O-CA 3.36Å; P292-Y374 WeakPolarHBondContact O-CB 3.43Å; P292-Y374 WeakPolarHBondContact O-CD2 3.34Å; S370-Y374 PolarHBondContact O-N 2.75Å; V371-Y374 WeakPolarHBondContact O-CB 3.47Å; V371-Y374 PolarHBondContact O-N 3.33Å; L372-Y374 VanDerWaalsContact C-N 3.35Å; Y374-Q377 PolarHBondContact O-N 2.82Å; Y374-K378 HydrophobicContact CE2-CD 4.41Å; Y374-K378 WeakPolarHBondContact O-CB 3.26Å; Y374-K378 PolarHBondContact O-N 3.46Å; Y374-T404 WeakPolarHBondContact CE1-OG1 3.2Å; Y374-T404 WeakPolarHBondContact OH-CB 3.35Å; Y374-T404 PolarHBondContact OH-OG1 2.93Å; Y374-L405 HydrophobicContact CE1-CD2 4.4Å
375	M	83.9	Confident	84.7	Confident	2 Å²	2	34.6 Å²	34.6	1%	0.01	16%	0.162	C	C	.	.	H	α-helix	trans	-62.3	-45.1	177	-177.7	-174	-77.7	0	0	111.6	V371 L372 Q377 K378 H379 V386 I397 E400 A401	V371-M375 PolarHBondContact O-N 3.07Å; L372-M375 PolarHBondContact O-N 3.49Å; M375-Q377 VanDerWaalsContact C-N 3.33Å; M375-Q377 PolarHBondContact O-N 3.45Å; M375-K378 PolarHBondContact O-N 3.43Å; M375-H379 PolarHBondContact O-CD2 3.48Å; M375-H379 VanDerWaalsContact O-CD2 3.32Å; M375-H379 PolarHBondContact O-N 3.25Å; M375-V386 HydrophobicContact CG-CG1 4.32Å; M375-V386 HydrophobicContact SD-CB 4.13Å; M375-V386 HydrophobicContact SD-CG1 3.86Å; M375-I397 HydrophobicContact CE-CG2 3.73Å; M375-I397 WeakPolarHBondContact CE-O 3.42Å; M375-I397 HydrophobicContact SD-CG2 3.76Å; M375-E400 HydrophobicContact CE-CB 3.81Å; M375-E400 HydrophobicContact CE-CG 3.77Å; M375-A401 HydrophobicContact CE-CB 3.64Å
376	A	84.3	Confident	83.8	Confident	1 Å²	1	34.6 Å²	34.6	1%	0.008	16%	0.162	C	C	.	.	H	α-helix	trans	-57.6	-46.1	177.5	0	0	0	0	0	111.5	L372 G373 N380 V381 V383 V386	L372-A376 WeakPolarHBondContact O-CB 3.45Å; L372-A376 PolarHBondContact O-N 3.46Å; G373-A376 PolarHBondContact O-N 2.97Å; A376-N380 WeakPolarHBondContact O-CA 3.49Å; A376-N380 PolarHBondContact O-N 3.15Å; A376-V381 CarbonylContact C-O 3.54Å; A376-V381 WeakPolarHBondContact CB-O 3.48Å; A376-V381 PolarHBondContact O-N 2.7Å; A376-V383 HydrophobicContact CB-CG2 3.78Å; A376-V386 HydrophobicContact CB-CG2 4.42Å
377	Q	85	Confident	82.7	Confident	93 Å²	93	33 Å²	33	44%	0.435	16%	0.157	S	C	.	.	H	α-helix	trans	-65.7	-42.6	176.5	-168.5	-178.3	24.9	0	0	112	P292 G373 Y374 M375 H379 N380	P292-Q377 PolarHBondContact O-OE1 3.41Å; G373-Q377 PolarHBondContact O-N 3.44Å; Y374-Q377 PolarHBondContact O-N 2.82Å; M375-Q377 VanDerWaalsContact C-N 3.33Å; M375-Q377 PolarHBondContact O-N 3.45Å; Q377-H379 PolarHBondContact O-N 2.99Å; Q377-N380 PolarHBondContact O-N 3.42Å
378	K	81.7	Confident	81.6	Confident	88 Å²	88	34.6 Å²	34.6	38%	0.383	17%	0.167	S	C	.	.	H	α-helix	trans	-64.2	-41.3	-177.5	-174.7	170.6	-177.8	178.9	0	112.6	Y374 M375 T404	Y374-K378 HydrophobicContact CE2-CD 4.41Å; Y374-K378 WeakPolarHBondContact O-CB 3.26Å; Y374-K378 PolarHBondContact O-N 3.46Å; M375-K378 PolarHBondContact O-N 3.43Å; K378-T404 HydrophobicContact CD-CG2 4.15Å; K378-T404 VanDerWaalsContact NZ-CB 3.33Å
379	H	76.1	Confident	80.7	Confident	14 Å²	14	39.6 Å²	39.6	7%	0.065	19%	0.19	C	C	.	.	H	α-helix	trans	-92.1	2.6	178.9	-62.8	-59.9	0	0	0	113.5	P196 Y209 M375 Q377 V381	P196-H379 WeakPolarHBondContact CB-CE1 3.44Å; P196-H379 PolarHBondContact O-CE1 2.88Å; P196-H379 PolarHBondContact O-ND1 2.95Å; Y209-H379 HydrophobicContact CE2-CB 4.33Å; M375-H379 PolarHBondContact O-CD2 3.48Å; M375-H379 VanDerWaalsContact O-CD2 3.32Å; M375-H379 PolarHBondContact O-N 3.25Å; Q377-H379 PolarHBondContact O-N 2.99Å; H379-V381 HydrophobicContact CB-CG1 4.3Å; H379-V381 HydrophobicContact CB-CG2 4.04Å; H379-V381 WeakPolarHBondContact O-CG1 3.3Å; H379-V381 PolarHBondContact O-N 2.95Å
380	N	77.9	Confident	80	Confident	151 Å²	151	40.7 Å²	40.7	81%	0.807	20%	0.202	S	C	*	.	T	Hydrogen-bonded Turn	trans	51.6	41.6	-176.8	-163.7	34.5	0	0	0	112.7	A376 Q377	A376-N380 WeakPolarHBondContact O-CA 3.49Å; A376-N380 PolarHBondContact O-N 3.15Å; Q377-N380 PolarHBondContact O-N 3.42Å
381	V	78.3	Confident	79.5	Confident	23 Å²	23	41.5 Å²	41.5	14%	0.139	21%	0.209	C	C	.	.			trans	-116.3	161.7	178.1	-63.9	0	0	0	0	110.3	Y209 A376 H379 V386	Y209-V381 HydrophobicContact CD2-CG1 3.62Å; Y209-V381 HydrophobicContact CE2-CG1 4.18Å; Y209-V381 HydrophobicContact CG-CG1 4.02Å; A376-V381 CarbonylContact C-O 3.54Å; A376-V381 WeakPolarHBondContact CB-O 3.48Å; A376-V381 PolarHBondContact O-N 2.7Å; H379-V381 HydrophobicContact CB-CG1 4.3Å; H379-V381 HydrophobicContact CB-CG2 4.04Å; H379-V381 WeakPolarHBondContact O-CG1 3.3Å; H379-V381 PolarHBondContact O-N 2.95Å; V381-V386 HydrophobicContact CG2-CG1 3.75Å
382	R	80	Confident	79.1	Confident	145 Å²	145	41.7 Å²	41.7	55%	0.547	21%	0.213	S	C	.	.			trans	-76.8	148.7	177.6	-59.1	171.1	-63.5	-172.5	2.1	109.9	Q384 D385	R382-Q384 HydrophobicContact CB-CG 3.83Å; R382-Q384 VanDerWaalsContact NH1-NE2 3.18Å; R382-Q384 PolarHBondContact O-N 2.95Å; R382-Q384 VanDerWaalsContact O-N 3.13Å; R382-D385 WeakPolarHBondContact CB-OD2 3.21Å; R382-D385 IonicContact CZ-OD2 3.68Å; R382-D385 IonicContact NE-OD2 2.67Å; R382-D385 PolarHBondContact NE-OD2 3.05Å; R382-D385 IonicContact NH2-OD1 2.65Å; R382-D385 PolarHBondContact NH2-OD1 3.2Å; R382-D385 IonicContact NH2-OD2 3.86Å; R382-D385 PolarHBondContact NH2-OD2 3.33Å; R382-D385 VanDerWaalsContact NH2-OD2 3.11Å; R382-D385 WeakPolarHBondContact O-CB 3.42Å; R382-D385 PolarHBondContact O-N 2.91Å
383	V	80.3	Confident	78.9	Confident	18 Å²	18	41.7 Å²	41.7	11%	0.109	21%	0.213	C	C	.	.	G	3₁₀ helix	trans	-55.3	-33.6	176.9	-180	0	0	0	0	112.2	A300 F369 A376 D385 V386 A387	A300-V383 HydrophobicContact CB-CB 4.16Å; A300-V383 HydrophobicContact CB-CG1 3.86Å; A300-V383 HydrophobicContact CB-CG2 4.28Å; F369-V383 HydrophobicContact CD1-CG1 4.32Å; F369-V383 HydrophobicContact CE1-CG1 4.18Å; A376-V383 HydrophobicContact CB-CG2 3.78Å; V383-D385 PolarHBondContact O-N 3.4Å; V383-V386 WeakPolarHBondContact O-CG2 3.43Å; V383-V386 PolarHBondContact O-N 2.8Å; V383-A387 VanDerWaalsContact O-CB 3.27Å; V383-A387 WeakPolarHBondContact O-CB 3.45Å; V383-A387 PolarHBondContact O-N 2.92Å
384	Q	73.5	Confident	78.9	Confident	93 Å²	93	41.8 Å²	41.8	44%	0.435	21%	0.214	S	C	.	.	G	3₁₀ helix	trans	-62.2	-27.5	175.6	65.4	-173.5	29	0	0	114.4	Y95 R382 V386	Y95-Q384 HydrophobicContact CE1-CB 4.31Å; Y95-Q384 VanDerWaalsContact OH-CA 3.3Å; Y95-Q384 WeakPolarHBondContact OH-CA 3.39Å; Y95-Q384 WeakPolarHBondContact OH-CB 3.39Å; Y95-Q384 PolarHBondContact OH-N 3.12Å; R382-Q384 HydrophobicContact CB-CG 3.83Å; R382-Q384 VanDerWaalsContact NH1-NE2 3.18Å; R382-Q384 PolarHBondContact O-N 2.95Å; R382-Q384 VanDerWaalsContact O-N 3.13Å; Q384-V386 VanDerWaalsContact C-N 3.28Å
385	D	70.5	Confident	79	Confident	10 Å²	10	40.8 Å²	40.8	5%	0.053	21%	0.21	C	C	.	.	G	3₁₀ helix	trans	-84.3	-9.9	-175.9	-59.1	-44.6	0	0	0	111.2	T208 A210 R382 V383	T208-D385 WeakPolarHBondContact CB-OD1 3.35Å; T208-D385 WeakPolarHBondContact CG2-OD1 3.35Å; A210-D385 WeakPolarHBondContact CB-O 3.36Å; A210-D385 PolarHBondContact N-O 2.92Å; A210-D385 VanDerWaalsContact N-O 3.16Å; R382-D385 WeakPolarHBondContact CB-OD2 3.21Å; R382-D385 IonicContact CZ-OD2 3.68Å; R382-D385 IonicContact NE-OD2 2.67Å; R382-D385 PolarHBondContact NE-OD2 3.05Å; R382-D385 IonicContact NH2-OD1 2.65Å; R382-D385 PolarHBondContact NH2-OD1 3.2Å; R382-D385 IonicContact NH2-OD2 3.86Å; R382-D385 PolarHBondContact NH2-OD2 3.33Å; R382-D385 VanDerWaalsContact NH2-OD2 3.11Å; R382-D385 WeakPolarHBondContact O-CB 3.42Å; R382-D385 PolarHBondContact O-N 2.91Å; V383-D385 PolarHBondContact O-N 3.4Å
386	V	73	Confident	79.2	Confident	0 Å²	0	41.5 Å²	41.5	0%	0	21%	0.214	C	C	.	.	T	Hydrogen-bonded Turn	trans	-113.8	-22.4	176	-63.3	0	0	0	0	113.2	Y209 L372 M375 A376 V381 V383 Q384 T388	Y209-V386 HydrophobicContact CD1-CG1 4.18Å; L372-V386 HydrophobicContact CD2-CB 4.43Å; L372-V386 HydrophobicContact CD2-CG2 4.21Å; M375-V386 HydrophobicContact CG-CG1 4.32Å; M375-V386 HydrophobicContact SD-CB 4.13Å; M375-V386 HydrophobicContact SD-CG1 3.86Å; A376-V386 HydrophobicContact CB-CG2 4.42Å; V381-V386 HydrophobicContact CG2-CG1 3.75Å; V383-V386 WeakPolarHBondContact O-CG2 3.43Å; V383-V386 PolarHBondContact O-N 2.8Å; Q384-V386 VanDerWaalsContact C-N 3.28Å; V386-T388 PolarHBondContact O-N 3.44Å; V386-T388 VanDerWaalsContact O-N 3.11Å
387	A	71.1	Confident	79.2	Confident	9 Å²	9	41.9 Å²	41.9	7%	0.074	22%	0.216	C	C	.	.			trans	-78.6	92.5	178.1	0	0	0	0	0	111	Y92 Y95 L372 V383	Y92-A387 WeakPolarHBondContact CE2-O 3.5Å; Y95-A387 HydrophobicContact CD1-CB 3.95Å; Y95-A387 HydrophobicContact CE1-CB 3.95Å; L372-A387 HydrophobicContact CD1-CB 4.38Å; V383-A387 VanDerWaalsContact O-CB 3.27Å; V383-A387 WeakPolarHBondContact O-CB 3.45Å; V383-A387 PolarHBondContact O-N 2.92Å
388	T	70.5	Confident	79.3	Confident	37 Å²	37	37.8 Å²	37.8	23%	0.227	20%	0.196	C	C	.	.			trans	-104.5	167.2	174.5	56.4	0	0	0	0	111.6	Y92 A210 V386 L393	Y92-T388 WeakPolarHBondContact CD2-O 3.45Å; A210-T388 HydrophobicContact CB-CG2 3.93Å; V386-T388 PolarHBondContact O-N 3.44Å; V386-T388 VanDerWaalsContact O-N 3.11Å; T388-L393 PolarHBondContact OG1-N 3.47Å
389	E	69.9	Low	79.7	Confident	107 Å²	107	33.6 Å²	33.6	50%	0.5	18%	0.178	S	C	.	.			trans	-105.1	156.7	175.8	71.8	-176.3	161.2	0	0	113.3	Y92	Y92-E389 HydrophobicContact CD1-CB 3.44Å; Y92-E389 VanDerWaalsContact CD1-CB 3.44Å; Y92-E389 HydrophobicContact CD1-CG 4.41Å; Y92-E389 HydrophobicContact CD2-CB 4.06Å; Y92-E389 HydrophobicContact CE1-CB 3.48Å; Y92-E389 VanDerWaalsContact CE1-CB 3.48Å; Y92-E389 HydrophobicContact CE1-CG 3.99Å; Y92-E389 WeakPolarHBondContact CE1-OE2 3.46Å; Y92-E389 HydrophobicContact CE2-CB 4.1Å; Y92-E389 HydrophobicContact CG-CB 3.72Å
390	G	77.4	Confident	80.1	Confident	25 Å²	25	33.3 Å²	33.3	26%	0.258	18%	0.177	S	C	.	.	T	Hydrogen-bonded Turn	trans	71.6	-144.1	170.9	0	0	0	0	0	114.1	G392 L393	G390-G392 VanDerWaalsContact C-N 3.3Å; G390-G392 PolarHBondContact O-N 3.32Å; G390-L393 PolarHBondContact O-N 3.11Å
391	A	81.3	Confident	80.5	Confident	18 Å²	18	26.2 Å²	26.2	15%	0.149	14%	0.139	C	C	.	.	H	α-helix	trans	-62.4	-33.4	-172.2	0	0	0	0	0	113.4	W88 W166 L393 V394 F395	W88-A391 HydrophobicContact CZ3-CB 4.24Å; W166-A391 HydrophobicContact CZ3-CB 4.06Å; A391-L393 VanDerWaalsContact C-N 3.3Å; A391-L393 PolarHBondContact O-N 3.45Å; A391-V394 PolarHBondContact O-N 3.06Å; A391-F395 HydrophobicContact CB-CD2 4.05Å; A391-F395 HydrophobicContact CB-CE2 4.47Å; A391-F395 WeakPolarHBondContact O-CB 3.26Å; A391-F395 VanDerWaalsContact O-CD2 3.3Å; A391-F395 WeakPolarHBondContact O-CD2 3.3Å; A391-F395 PolarHBondContact O-N 3.45Å
392	G	82.1	Confident	81	Confident	18 Å²	18	25.4 Å²	25.4	19%	0.186	13%	0.134	C	C	.	.	H	α-helix	trans	-60.4	-38.7	178.6	0	0	0	0	0	112.7	G390 V394 I396 I397	G390-G392 VanDerWaalsContact C-N 3.3Å; G390-G392 PolarHBondContact O-N 3.32Å; G392-V394 VanDerWaalsContact C-N 3.33Å; G392-V394 PolarHBondContact O-N 2.95Å; G392-I396 WeakPolarHBondContact O-CA 3.32Å; G392-I396 WeakPolarHBondContact O-CB 3.5Å; G392-I396 PolarHBondContact O-N 3.45Å; G392-I397 PolarHBondContact O-N 3.34Å
393	L	83.2	Confident	81.4	Confident	3 Å²	3	19 Å²	19	2%	0.016	11%	0.112	C	C	.	.	I	π-helix	trans	-61	-45.5	177.8	-174.7	66.4	0	0	0	111.1	W88 L372 T388 G390 A391 I397 Y398	W88-L393 HydrophobicContact CB-CD2 4.18Å; L372-L393 HydrophobicContact CD1-CD1 4.36Å; L372-L393 HydrophobicContact CD2-CD1 4.19Å; T388-L393 PolarHBondContact OG1-N 3.47Å; G390-L393 PolarHBondContact O-N 3.11Å; A391-L393 VanDerWaalsContact C-N 3.3Å; A391-L393 PolarHBondContact O-N 3.45Å; L393-I397 HydrophobicContact CD1-CB 4.23Å; L393-I397 HydrophobicContact CD1-CG2 4.32Å; L393-I397 WeakPolarHBondContact O-CB 3.26Å; L393-I397 PolarHBondContact O-N 2.95Å; L393-Y398 HydrophobicContact CD1-CE2 4.27Å; L393-Y398 HydrophobicContact CD2-CE2 4.28Å; L393-Y398 HydrophobicContact CG-CD2 4.33Å; L393-Y398 HydrophobicContact CG-CE2 3.81Å; L393-Y398 WeakPolarHBondContact O-CD2 3.34Å; L393-Y398 PolarHBondContact O-N 3Å
394	V	88.2	Confident	81.6	Confident	1 Å²	1	20.1 Å²	20.1	1%	0.006	12%	0.118	C	C	.	.	I	π-helix	trans	-80.1	-35.7	-174.4	174	0	0	0	0	114.3	W88 A391 G392 Y398 P399 F415 L419	W88-V394 HydrophobicContact CB-CG2 3.59Å; W88-V394 HydrophobicContact CD2-CG2 4.21Å; W88-V394 HydrophobicContact CE3-CB 3.95Å; W88-V394 HydrophobicContact CE3-CG2 3.57Å; W88-V394 HydrophobicContact CG-CG2 4.28Å; A391-V394 PolarHBondContact O-N 3.06Å; G392-V394 VanDerWaalsContact C-N 3.33Å; G392-V394 PolarHBondContact O-N 2.95Å; V394-Y398 HydrophobicContact CG2-CD2 4.46Å; V394-P399 VanDerWaalsContact O-CD 3.22Å; V394-P399 WeakPolarHBondContact O-CD 3.49Å; V394-F415 HydrophobicContact CG1-CE1 4.23Å; V394-F415 HydrophobicContact CG1-CZ 4.14Å; V394-L419 HydrophobicContact CG1-CD1 3.21Å; V394-L419 HydrophobicContact CG1-CD2 3.72Å; V394-L419 HydrophobicContact CG1-CG 4.09Å; V394-L419 HydrophobicContact CG2-CD2 4.47Å
395	F	91.1	Very high	82.2	Confident	0 Å²	0	16.3 Å²	16.3	0%	0	10%	0.101	C	C	.	.	I	π-helix	trans	-104.7	-7.7	-174.2	-63.1	-70	0	0	0	114.1	W88 I163 W166 Y170 Y221 A391 F416	W88-F395 HydrophobicContact CZ3-CE2 4.4Å; I163-F395 HydrophobicContact CG2-CE2 4.1Å; I163-F395 HydrophobicContact CG2-CZ 4.21Å; W166-F395 HydrophobicContact CB-CE1 3.84Å; W166-F395 HydrophobicContact CB-CE2 4.27Å; W166-F395 HydrophobicContact CB-CZ 3.7Å; W166-F395 HydrophobicContact CE3-CD2 4.21Å; W166-F395 AromaticContact CE3-CE2 3.81Å; W166-F395 HydrophobicContact CE3-CE2 3.81Å; W166-F395 HydrophobicContact CE3-CZ 4.36Å; Y170-F395 AromaticContact CD2-CD1 3.56Å; Y170-F395 HydrophobicContact CD2-CD1 3.56Å; Y170-F395 AromaticContact CD2-CE1 3.99Å; Y170-F395 HydrophobicContact CD2-CE1 3.99Å; Y170-F395 HydrophobicContact CE2-CB 4.17Å; Y170-F395 AromaticContact CE2-CD1 3.57Å; Y170-F395 HydrophobicContact CE2-CD1 3.57Å; Y170-F395 HydrophobicContact CE2-CE1 4.38Å; Y170-F395 HydrophobicContact CE2-CG 4.21Å; Y170-F395 HydrophobicContact CG-CD1 4.13Å; Y170-F395 PolarHBondContact OH-O 3.38Å; Y170-F395 VanDerWaalsContact OH-O 3.09Å; Y221-F395 HydrophobicContact CD2-CB 3.55Å; Y221-F395 HydrophobicContact CD2-CG 4.3Å; Y221-F395 HydrophobicContact CE2-CB 3.62Å; Y221-F395 HydrophobicContact CE2-CD2 4.14Å; Y221-F395 AromaticContact CE2-CG 3.98Å; Y221-F395 HydrophobicContact CE2-CG 3.98Å; Y221-F395 HydrophobicContact CG-CB 4.18Å; A391-F395 HydrophobicContact CB-CD2 4.05Å; A391-F395 HydrophobicContact CB-CE2 4.47Å; A391-F395 WeakPolarHBondContact O-CB 3.26Å; A391-F395 VanDerWaalsContact O-CD2 3.3Å; A391-F395 WeakPolarHBondContact O-CD2 3.3Å; A391-F395 PolarHBondContact O-N 3.45Å; F395-F416 HydrophobicContact CD1-CE1 4.11Å; F395-F416 HydrophobicContact CE1-CE1 4.15Å
396	I	88	Confident	83	Confident	17 Å²	17	20.5 Å²	20.5	9%	0.087	13%	0.129	C	C	.	.	I	π-helix	trans	-117.2	-62.1	176.1	-54.7	174.8	0	0	0	110.1	A217 A218 Y221 G392 P399 E400	A217-I396 HydrophobicContact CB-CG2 4.31Å; A217-I396 WeakPolarHBondContact CB-O 3.32Å; A218-I396 HydrophobicContact CB-CD1 4.31Å; A218-I396 HydrophobicContact CB-CG2 3.74Å; Y221-I396 HydrophobicContact CD1-CD1 3.82Å; Y221-I396 HydrophobicContact CD1-CG1 3.87Å; Y221-I396 HydrophobicContact CG-CD1 4.48Å; Y221-I396 HydrophobicContact CG-CG1 4.06Å; G392-I396 WeakPolarHBondContact O-CA 3.32Å; G392-I396 WeakPolarHBondContact O-CB 3.5Å; G392-I396 PolarHBondContact O-N 3.45Å; I396-P399 WeakPolarHBondContact O-CD 3.22Å; I396-E400 VanDerWaalsContact O-CB 3.29Å; I396-E400 WeakPolarHBondContact O-CB 3.4Å; I396-E400 PolarHBondContact O-N 2.83Å; I396-E400 VanDerWaalsContact O-N 3.11Å
397	I	84.9	Confident	83.7	Confident	10 Å²	10	23 Å²	23	5%	0.051	16%	0.155	C	C	.	.	I	π-helix	trans	-72	-44.9	-168.5	-56.3	-62.8	0	0	0	111.9	L372 M375 G392 L393 E400 A401	L372-I397 HydrophobicContact CD2-CG2 3.35Å; M375-I397 HydrophobicContact CE-CG2 3.73Å; M375-I397 WeakPolarHBondContact CE-O 3.42Å; M375-I397 HydrophobicContact SD-CG2 3.76Å; G392-I397 PolarHBondContact O-N 3.34Å; L393-I397 HydrophobicContact CD1-CB 4.23Å; L393-I397 HydrophobicContact CD1-CG2 4.32Å; L393-I397 WeakPolarHBondContact O-CB 3.26Å; L393-I397 PolarHBondContact O-N 2.95Å; I397-E400 PolarHBondContact O-N 3.33Å; I397-A401 PolarHBondContact O-N 2.92Å
398	Y	86.1	Confident	84.6	Confident	7 Å²	7	23.4 Å²	23.4	3%	0.027	16%	0.157	C	C	.	.	H	α-helix	trans	-63.6	-48.7	176.2	-83	-69	0	0	0	114	I368 V371 L393 V394 E400 A401 I402 F415	I368-Y398 WeakPolarHBondContact CA-OH 3.46Å; I368-Y398 WeakPolarHBondContact CB-OH 3.17Å; I368-Y398 HydrophobicContact CD1-CE1 3.96Å; I368-Y398 HydrophobicContact CD1-CE2 4.14Å; I368-Y398 VanDerWaalsContact CD1-CZ 3.44Å; I368-Y398 WeakPolarHBondContact CD1-OH 3.29Å; I368-Y398 HydrophobicContact CG1-CE2 4.3Å; I368-Y398 WeakPolarHBondContact CG1-OH 3.47Å; I368-Y398 WeakPolarHBondContact CG2-OH 3.32Å; V371-Y398 HydrophobicContact CB-CE1 4.35Å; V371-Y398 HydrophobicContact CG1-CD1 4.46Å; V371-Y398 HydrophobicContact CG1-CE1 4.32Å; L393-Y398 HydrophobicContact CD1-CE2 4.27Å; L393-Y398 HydrophobicContact CD2-CE2 4.28Å; L393-Y398 HydrophobicContact CG-CD2 4.33Å; L393-Y398 HydrophobicContact CG-CE2 3.81Å; L393-Y398 WeakPolarHBondContact O-CD2 3.34Å; L393-Y398 PolarHBondContact O-N 3Å; V394-Y398 HydrophobicContact CG2-CD2 4.46Å; Y398-E400 PolarHBondContact O-N 2.93Å; Y398-A401 PolarHBondContact O-N 3.01Å; Y398-I402 WeakPolarHBondContact O-CB 3.47Å; Y398-I402 VanDerWaalsContact O-CG1 3.29Å; Y398-I402 WeakPolarHBondContact O-CG1 3.44Å; Y398-I402 PolarHBondContact O-N 3.29Å; Y398-F415 VanDerWaalsContact CB-CZ 3.4Å; Y398-F415 HydrophobicContact CD1-CE2 4.02Å; Y398-F415 HydrophobicContact CD1-CZ 4.09Å; Y398-F415 HydrophobicContact CD2-CE2 4.19Å; Y398-F415 AromaticContact CD2-CZ 3.66Å; Y398-F415 HydrophobicContact CD2-CZ 3.66Å; Y398-F415 HydrophobicContact CG-CE1 4.15Å; Y398-F415 AromaticContact CG-CE2 3.82Å; Y398-F415 HydrophobicContact CG-CE2 3.82Å; Y398-F415 AromaticContact CG-CZ 3.42Å; Y398-F415 HydrophobicContact CG-CZ 3.42Å; Y398-F415 VanDerWaalsContact CG-CZ 3.42Å
399	P	89.4	Confident	85.7	Confident	0 Å²	0	23.5 Å²	23.5	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-60	-37.7	179	-28.4	40.2	0	0	0	111.7	Y170 W181 V394 I396 I402 A403 F416	Y170-P399 HydrophobicContact CE1-CG 4.27Å; W181-P399 HydrophobicContact CD2-CB 4.04Å; W181-P399 HydrophobicContact CG-CB 4.07Å; W181-P399 HydrophobicContact CZ2-CB 4.2Å; W181-P399 PolarHBondContact NE1-O 3.3Å; V394-P399 VanDerWaalsContact O-CD 3.22Å; V394-P399 WeakPolarHBondContact O-CD 3.49Å; I396-P399 WeakPolarHBondContact O-CD 3.22Å; P399-I402 PolarHBondContact O-N 3.42Å; P399-A403 WeakPolarHBondContact O-CB 3.44Å; P399-A403 PolarHBondContact O-N 2.95Å; P399-F416 HydrophobicContact CG-CZ 3.73Å
400	E	86.3	Confident	86.8	Confident	8 Å²	8	24.5 Å²	24.5	4%	0.037	16%	0.161	C	C	.	.	H	α-helix	trans	-61.4	-50	173	-179.2	175.1	-176.2	0	0	111.8	Y209 T215 A217 M375 I396 I397 Y398 I402 A403	Y209-E400 PolarHBondContact OH-OE1 3.46Å; T215-E400 WeakPolarHBondContact CG2-OE1 3.43Å; A217-E400 HydrophobicContact CB-CB 3.83Å; M375-E400 HydrophobicContact CE-CB 3.81Å; M375-E400 HydrophobicContact CE-CG 3.77Å; I396-E400 VanDerWaalsContact O-CB 3.29Å; I396-E400 WeakPolarHBondContact O-CB 3.4Å; I396-E400 PolarHBondContact O-N 2.83Å; I396-E400 VanDerWaalsContact O-N 3.11Å; I397-E400 PolarHBondContact O-N 3.33Å; Y398-E400 PolarHBondContact O-N 2.93Å; E400-I402 PolarHBondContact O-N 3.42Å; E400-A403 WeakPolarHBondContact O-CB 3.46Å; E400-A403 PolarHBondContact O-N 3.48Å
401	A	86.1	Confident	87.5	Confident	2 Å²	2	25 Å²	25	2%	0.017	16%	0.155	C	C	.	.	H	α-helix	trans	-61.2	-46	176.9	0	0	0	0	0	112.3	V371 M375 I397 Y398 A403 T404	V371-A401 HydrophobicContact CG1-CB 3.29Å; M375-A401 HydrophobicContact CE-CB 3.64Å; I397-A401 PolarHBondContact O-N 2.92Å; Y398-A401 PolarHBondContact O-N 3.01Å; A401-A403 VanDerWaalsContact C-N 3.29Å; A401-A403 PolarHBondContact O-N 3.48Å; A401-T404 PolarHBondContact O-N 2.89Å; A401-T404 VanDerWaalsContact O-N 3.17Å; A401-T404 PolarHBondContact O-OG1 3.12Å
402	I	89.1	Confident	88.1	Confident	6 Å²	6	24.2 Å²	24.2	3%	0.031	15%	0.148	C	C	.	.	H	α-helix	trans	-61.4	-39	180	-73.2	169.3	0	0	0	111.1	Y398 P399 E400 T404 L405 S408 W411 A412 F415	Y398-I402 WeakPolarHBondContact O-CB 3.47Å; Y398-I402 VanDerWaalsContact O-CG1 3.29Å; Y398-I402 WeakPolarHBondContact O-CG1 3.44Å; Y398-I402 PolarHBondContact O-N 3.29Å; P399-I402 PolarHBondContact O-N 3.42Å; E400-I402 PolarHBondContact O-N 3.42Å; I402-T404 PolarHBondContact O-N 2.91Å; I402-T404 VanDerWaalsContact O-N 3.17Å; I402-L405 WeakPolarHBondContact O-CB 3.38Å; I402-L405 PolarHBondContact O-N 2.85Å; I402-S408 WeakPolarHBondContact CG2-O 3.38Å; I402-S408 WeakPolarHBondContact O-CB 3.36Å; I402-W411 HydrophobicContact CG2-CB 3.63Å; I402-A412 HydrophobicContact CG2-CB 3.95Å; I402-F415 HydrophobicContact CD1-CB 3.72Å; I402-F415 HydrophobicContact CD1-CD1 3.84Å; I402-F415 HydrophobicContact CD1-CD2 4.23Å; I402-F415 HydrophobicContact CD1-CG 3.67Å
403	A	87.9	Confident	88.7	Confident	10 Å²	10	25.5 Å²	25.5	8%	0.083	15%	0.15	C	C	.	.	H	α-helix	trans	-59.8	-26.9	179.3	0	0	0	0	0	112.8	L179 L182 P399 E400 A401	L179-A403 HydrophobicContact CD1-CB 4.25Å; L182-A403 HydrophobicContact CD1-CB 3.77Å; P399-A403 WeakPolarHBondContact O-CB 3.44Å; P399-A403 PolarHBondContact O-N 2.95Å; E400-A403 WeakPolarHBondContact O-CB 3.46Å; E400-A403 PolarHBondContact O-N 3.48Å; A401-A403 VanDerWaalsContact C-N 3.29Å; A401-A403 PolarHBondContact O-N 3.48Å
404	T	84.4	Confident	89.1	Confident	41 Å²	41	27 Å²	27	25%	0.252	16%	0.159	S	C	.	.	T	Hydrogen-bonded Turn	trans	-81.8	-11	177.1	72.9	0	0	0	0	114.8	Y374 K378 A401 I402	Y374-T404 WeakPolarHBondContact CE1-OG1 3.2Å; Y374-T404 WeakPolarHBondContact OH-CB 3.35Å; Y374-T404 PolarHBondContact OH-OG1 2.93Å; K378-T404 HydrophobicContact CD-CG2 4.15Å; K378-T404 VanDerWaalsContact NZ-CB 3.33Å; A401-T404 PolarHBondContact O-N 2.89Å; A401-T404 VanDerWaalsContact O-N 3.17Å; A401-T404 PolarHBondContact O-OG1 3.12Å; I402-T404 PolarHBondContact O-N 2.91Å; I402-T404 VanDerWaalsContact O-N 3.17Å
405	L	85.4	Confident	89.4	Confident	13 Å²	13	27 Å²	27	7%	0.068	16%	0.159	C	C	.	.	S	Bend	trans	-82.1	144.6	-177.7	-59.4	-179.8	0	0	0	111.1	R287 L291 Y374 I402 G407 S408 W411	R287-L405 HydrophobicContact CG-CD1 4.39Å; L291-L405 HydrophobicContact CD1-CD2 3.87Å; L291-L405 HydrophobicContact CD2-CD2 3.53Å; L291-L405 HydrophobicContact CG-CD2 4.33Å; Y374-L405 HydrophobicContact CE1-CD2 4.4Å; I402-L405 WeakPolarHBondContact O-CB 3.38Å; I402-L405 PolarHBondContact O-N 2.85Å; L405-G407 PolarHBondContact O-N 3.1Å; L405-S408 WeakPolarHBondContact O-CB 3.32Å; L405-S408 PolarHBondContact O-N 3.38Å; L405-S408 VanDerWaalsContact O-N 3.11Å; L405-W411 HydrophobicContact CD1-CD2 4.46Å; L405-W411 HydrophobicContact CD1-CG 4.2Å
406	P	86.8	Confident	89.6	Confident	98 Å²	98	27 Å²	27	64%	0.636	16%	0.159	S	C	*	.	T	Hydrogen-bonded Turn	trans	-62	132.4	169.4	27.2	-33.7	0	0	0	109.9	W411	P406-W411 PolarHBondContact O-NE1 3.28Å
407	G	88.8	Confident	89.9	Confident	53 Å²	53	29.1 Å²	29.1	55%	0.546	17%	0.17	S	C	.	.	T	Hydrogen-bonded Turn	trans	71.7	32	-172.7	0	0	0	0	0	113.6	L405 T409 F410	L405-G407 PolarHBondContact O-N 3.1Å; G407-T409 PolarHBondContact O-N 3.06Å; G407-T409 VanDerWaalsContact O-N 3.09Å; G407-F410 WeakPolarHBondContact O-CB 3.46Å; G407-F410 PolarHBondContact O-N 3.37Å
408	S	90.6	Very high	90.3	Very high	18 Å²	18	28.7 Å²	28.7	13%	0.126	17%	0.168	C	C	.	.	H	α-helix	trans	-47.3	-37.2	-176.6	55.5	0	0	0	0	114.6	I402 L405 F410 W411 A412	I402-S408 WeakPolarHBondContact CG2-O 3.38Å; I402-S408 WeakPolarHBondContact O-CB 3.36Å; L405-S408 WeakPolarHBondContact O-CB 3.32Å; L405-S408 PolarHBondContact O-N 3.38Å; L405-S408 VanDerWaalsContact O-N 3.11Å; S408-F410 PolarHBondContact O-N 3.02Å; S408-W411 PolarHBondContact O-N 3.35Å; S408-A412 WeakPolarHBondContact O-CB 3.28Å; S408-A412 PolarHBondContact O-N 3.25Å
409	T	93.5	Very high	90.7	Very high	39 Å²	39	28.4 Å²	28.4	24%	0.239	17%	0.167	C	C	.	.	H	α-helix	trans	-53.3	-47.1	173.5	-56.5	0	0	0	0	113	S174 T176 G407 A412 I413	S174-T409 WeakPolarHBondContact O-CG2 3.48Å; T176-T409 VanDerWaalsContact O-CG2 3.22Å; T176-T409 WeakPolarHBondContact O-CG2 3.4Å; T176-T409 PolarHBondContact O-OG1 3.4Å; G407-T409 PolarHBondContact O-N 3.06Å; G407-T409 VanDerWaalsContact O-N 3.09Å; T409-A412 PolarHBondContact O-N 3.19Å; T409-I413 HydrophobicContact CG2-CD1 3.92Å; T409-I413 VanDerWaalsContact O-CG1 3.28Å; T409-I413 WeakPolarHBondContact O-CG1 3.26Å; T409-I413 PolarHBondContact O-N 3.15Å
410	F	92.6	Very high	90.9	Very high	127 Å²	127	29.5 Å²	29.5	56%	0.557	17%	0.173	S	C	*	.	H	α-helix	trans	-63.9	-46.4	-179.7	170.5	-99	0	0	0	111	G407 S408 A412 I413 V414	G407-F410 WeakPolarHBondContact O-CB 3.46Å; G407-F410 PolarHBondContact O-N 3.37Å; S408-F410 PolarHBondContact O-N 3.02Å; F410-A412 PolarHBondContact O-N 2.87Å; F410-I413 PolarHBondContact O-N 3.08Å; F410-V414 HydrophobicContact CD2-CG2 4.28Å; F410-V414 HydrophobicContact CE1-CG2 4.2Å; F410-V414 HydrophobicContact CE2-CG2 3.88Å; F410-V414 HydrophobicContact CZ-CG2 3.84Å; F410-V414 VanDerWaalsContact O-CG2 3.32Å; F410-V414 WeakPolarHBondContact O-CG2 3.42Å; F410-V414 PolarHBondContact O-N 3.12Å
411	W	91.8	Very high	91.3	Very high	37 Å²	37	29.5 Å²	29.5	14%	0.14	17%	0.173	C	C	.	.	H	α-helix	trans	-62.5	-41.1	179	-66.9	110.4	0	0	0	112.3	V283 L284 R287 I402 L405 P406 S408 F415	V283-W411 HydrophobicContact CG1-CH2 3.85Å; V283-W411 HydrophobicContact CG1-CZ3 3.72Å; L284-W411 HydrophobicContact CD2-CE3 3.93Å; L284-W411 HydrophobicContact CD2-CZ3 4.15Å; R287-W411 HydrophobicContact CB-CH2 3.68Å; R287-W411 HydrophobicContact CB-CZ2 4.26Å; R287-W411 HydrophobicContact CB-CZ3 4.03Å; R287-W411 HydrophobicContact CG-CH2 3.78Å; R287-W411 HydrophobicContact CG-CZ2 3.86Å; R287-W411 HydrophobicContact CG-CZ3 4.22Å; I402-W411 HydrophobicContact CG2-CB 3.63Å; L405-W411 HydrophobicContact CD1-CD2 4.46Å; L405-W411 HydrophobicContact CD1-CG 4.2Å; P406-W411 PolarHBondContact O-NE1 3.28Å; S408-W411 PolarHBondContact O-N 3.35Å; W411-F415 VanDerWaalsContact O-CB 3.22Å; W411-F415 WeakPolarHBondContact O-CB 3.48Å; W411-F415 PolarHBondContact O-N 2.92Å
412	A	93.7	Very high	91.7	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-64.1	-47.9	177.5	0	0	0	0	0	111.4	L179 W181 I402 S408 T409 F410 V414 F415 F416	L179-A412 HydrophobicContact CD1-CB 4.23Å; L179-A412 HydrophobicContact CD2-CB 4.13Å; W181-A412 HydrophobicContact CZ2-CB 4.11Å; I402-A412 HydrophobicContact CG2-CB 3.95Å; S408-A412 WeakPolarHBondContact O-CB 3.28Å; S408-A412 PolarHBondContact O-N 3.25Å; T409-A412 PolarHBondContact O-N 3.19Å; F410-A412 PolarHBondContact O-N 2.87Å; A412-V414 PolarHBondContact O-N 3.49Å; A412-F415 PolarHBondContact O-N 3.15Å; A412-F416 HydrophobicContact CB-CD2 4.46Å; A412-F416 HydrophobicContact CB-CE2 4.43Å; A412-F416 WeakPolarHBondContact O-CD2 3.41Å; A412-F416 PolarHBondContact O-N 3.04Å
413	I	94.4	Very high	92	Very high	46 Å²	46	29.4 Å²	29.4	24%	0.236	17%	0.172	C	C	.	.	H	α-helix	trans	-57.6	-49.1	177.9	-70.5	168.6	0	0	0	110.8	L171 T409 F410 F415 F416 I417	L171-I413 HydrophobicContact CD1-CB 4.41Å; L171-I413 HydrophobicContact CD1-CG2 4.02Å; T409-I413 HydrophobicContact CG2-CD1 3.92Å; T409-I413 VanDerWaalsContact O-CG1 3.28Å; T409-I413 WeakPolarHBondContact O-CG1 3.26Å; T409-I413 PolarHBondContact O-N 3.15Å; F410-I413 PolarHBondContact O-N 3.08Å; I413-F415 PolarHBondContact O-N 2.88Å; I413-F416 PolarHBondContact O-N 2.83Å; I413-I417 HydrophobicContact CG2-CD1 3.73Å; I413-I417 WeakPolarHBondContact O-CB 3.16Å; I413-I417 VanDerWaalsContact O-CG1 3.23Å; I413-I417 WeakPolarHBondContact O-CG1 3.29Å; I413-I417 PolarHBondContact O-N 3.23Å
414	V	92.9	Very high	92.3	Very high	33 Å²	33	29.1 Å²	29.1	20%	0.2	17%	0.17	C	C	.	.	H	α-helix	trans	-64.6	-40.3	-179	174.5	0	0	0	0	111.4	V280 F410 A412 M418	V280-V414 HydrophobicContact CB-CG1 4.09Å; V280-V414 HydrophobicContact CG1-CG1 3.64Å; V280-V414 HydrophobicContact CG2-CG1 3.43Å; V280-V414 VanDerWaalsContact CG2-CG1 3.43Å; F410-V414 HydrophobicContact CD2-CG2 4.28Å; F410-V414 HydrophobicContact CE1-CG2 4.2Å; F410-V414 HydrophobicContact CE2-CG2 3.88Å; F410-V414 HydrophobicContact CZ-CG2 3.84Å; F410-V414 VanDerWaalsContact O-CG2 3.32Å; F410-V414 WeakPolarHBondContact O-CG2 3.42Å; F410-V414 PolarHBondContact O-N 3.12Å; A412-V414 PolarHBondContact O-N 3.49Å; V414-M418 PolarHBondContact O-N 3.24Å
415	F	93	Very high	92.8	Very high	1 Å²	1	27.5 Å²	27.5	0%	0.004	16%	0.159	C	C	.	.	H	α-helix	trans	-64	-47	177.1	178.3	-106.6	0	0	0	112.6	L284 V394 Y398 I402 W411 A412 I413 M418 L419	L284-F415 HydrophobicContact CD1-CD2 3.98Å; V394-F415 HydrophobicContact CG1-CE1 4.23Å; V394-F415 HydrophobicContact CG1-CZ 4.14Å; Y398-F415 VanDerWaalsContact CB-CZ 3.4Å; Y398-F415 HydrophobicContact CD1-CE2 4.02Å; Y398-F415 HydrophobicContact CD1-CZ 4.09Å; Y398-F415 HydrophobicContact CD2-CE2 4.19Å; Y398-F415 AromaticContact CD2-CZ 3.66Å; Y398-F415 HydrophobicContact CD2-CZ 3.66Å; Y398-F415 HydrophobicContact CG-CE1 4.15Å; Y398-F415 AromaticContact CG-CE2 3.82Å; Y398-F415 HydrophobicContact CG-CE2 3.82Å; Y398-F415 AromaticContact CG-CZ 3.42Å; Y398-F415 HydrophobicContact CG-CZ 3.42Å; Y398-F415 VanDerWaalsContact CG-CZ 3.42Å; I402-F415 HydrophobicContact CD1-CB 3.72Å; I402-F415 HydrophobicContact CD1-CD1 3.84Å; I402-F415 HydrophobicContact CD1-CD2 4.23Å; I402-F415 HydrophobicContact CD1-CG 3.67Å; W411-F415 VanDerWaalsContact O-CB 3.22Å; W411-F415 WeakPolarHBondContact O-CB 3.48Å; W411-F415 PolarHBondContact O-N 2.92Å; A412-F415 PolarHBondContact O-N 3.15Å; I413-F415 PolarHBondContact O-N 2.88Å; F415-M418 HydrophobicContact CD2-CE 3.6Å; F415-M418 HydrophobicContact CE2-CE 3.69Å; F415-M418 WeakPolarHBondContact O-CB 3.25Å; F415-M418 PolarHBondContact O-N 2.84Å; F415-L419 HydrophobicContact CD1-CD1 3.92Å; F415-L419 HydrophobicContact CE1-CD1 3.47Å; F415-L419 VanDerWaalsContact CE1-CD1 3.47Å; F415-L419 HydrophobicContact CE1-CG 4.37Å; F415-L419 HydrophobicContact CZ-CD1 3.81Å; F415-L419 HydrophobicContact CZ-CD2 4.48Å; F415-L419 HydrophobicContact CZ-CG 4.34Å; F415-L419 WeakPolarHBondContact O-CG 3.41Å; F415-L419 PolarHBondContact O-N 2.74Å
416	F	95.3	Very high	93.2	Very high	0 Å²	0	27.4 Å²	27.4	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-72.9	-27.8	179.3	-69.8	-64.3	0	0	0	113.3	Y170 L171 S174 W181 F395 P399 A412 I413 L419 L420	Y170-F416 VanDerWaalsContact CB-CZ 3.44Å; Y170-F416 AromaticContact CD1-CE1 3.79Å; Y170-F416 HydrophobicContact CD1-CE1 3.79Å; Y170-F416 AromaticContact CD1-CE2 3.76Å; Y170-F416 HydrophobicContact CD1-CE2 3.76Å; Y170-F416 AromaticContact CD1-CZ 3.2Å; Y170-F416 HydrophobicContact CD1-CZ 3.2Å; Y170-F416 HydrophobicContact CD2-CE1 4.48Å; Y170-F416 HydrophobicContact CE1-CZ 4.1Å; Y170-F416 HydrophobicContact CG-CD1 4.3Å; Y170-F416 AromaticContact CG-CE1 3.63Å; Y170-F416 HydrophobicContact CG-CE1 3.63Å; Y170-F416 HydrophobicContact CG-CE2 4.16Å; Y170-F416 AromaticContact CG-CZ 3.54Å; Y170-F416 HydrophobicContact CG-CZ 3.54Å; L171-F416 HydrophobicContact CB-CB 3.96Å; L171-F416 HydrophobicContact CD1-CB 4.35Å; S174-F416 WeakPolarHBondContact OG-CD2 3.49Å; W181-F416 AromaticContact CH2-CE2 3.87Å; W181-F416 HydrophobicContact CH2-CE2 3.87Å; W181-F416 HydrophobicContact CZ2-CE2 4Å; F395-F416 HydrophobicContact CD1-CE1 4.11Å; F395-F416 HydrophobicContact CE1-CE1 4.15Å; P399-F416 HydrophobicContact CG-CZ 3.73Å; A412-F416 HydrophobicContact CB-CD2 4.46Å; A412-F416 HydrophobicContact CB-CE2 4.43Å; A412-F416 WeakPolarHBondContact O-CD2 3.41Å; A412-F416 PolarHBondContact O-N 3.04Å; I413-F416 PolarHBondContact O-N 2.83Å; F416-L419 HydrophobicContact CD1-CD1 3.68Å; F416-L419 HydrophobicContact CE1-CD1 3.99Å; F416-L419 PolarHBondContact O-N 3.3Å; F416-L420 VanDerWaalsContact O-CB 3.28Å; F416-L420 WeakPolarHBondContact O-CB 3.36Å; F416-L420 PolarHBondContact O-N 3.33Å
417	I	94.4	Very high	93.6	Very high	63 Å²	63	23.1 Å²	23.1	32%	0.323	13%	0.132	S	C	.	.	H	α-helix	trans	-62.9	-43.1	167.5	-72.7	169.3	0	0	0	110.6	L171 I413 L420 T421	L171-I417 HydrophobicContact CD1-CD1 4.39Å; L171-I417 HydrophobicContact CD1-CG1 3.84Å; L171-I417 HydrophobicContact CD2-CG1 4.07Å; I413-I417 HydrophobicContact CG2-CD1 3.73Å; I413-I417 WeakPolarHBondContact O-CB 3.16Å; I413-I417 VanDerWaalsContact O-CG1 3.23Å; I413-I417 WeakPolarHBondContact O-CG1 3.29Å; I413-I417 PolarHBondContact O-N 3.23Å; I417-L420 PolarHBondContact O-N 3.37Å; I417-T421 HydrophobicContact CG2-CG2 4.37Å; I417-T421 WeakPolarHBondContact O-CB 3.29Å; I417-T421 WeakPolarHBondContact O-CG2 3.37Å; I417-T421 PolarHBondContact O-N 3.07Å; I417-T421 PolarHBondContact O-OG1 3.01Å
418	M	94.1	Very high	93.9	Very high	0 Å²	0	20.7 Å²	20.7	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-59.3	-47.7	175.2	170.4	-173.8	78.2	0	0	111.5	P277 V280 L281 L284 V414 F415 L420 T421 L422	P277-M418 HydrophobicContact CB-CG 4.01Å; V280-M418 HydrophobicContact CB-CB 3.86Å; V280-M418 HydrophobicContact CB-CG 4.18Å; V280-M418 HydrophobicContact CB-SD 3.88Å; V280-M418 HydrophobicContact CG1-CB 3.72Å; V280-M418 HydrophobicContact CG1-CE 4.43Å; V280-M418 HydrophobicContact CG1-CG 4.17Å; V280-M418 HydrophobicContact CG1-SD 3.56Å; V280-M418 VanDerWaalsContact CG1-SD 3.56Å; V280-M418 HydrophobicContact CG2-CB 4.06Å; L281-M418 HydrophobicContact CD2-CE 4.43Å; L281-M418 HydrophobicContact CD2-SD 3.77Å; L281-M418 HydrophobicContact CG-SD 3.79Å; L284-M418 HydrophobicContact CD1-CE 4.21Å; L284-M418 HydrophobicContact CD1-SD 4.46Å; V414-M418 PolarHBondContact O-N 3.24Å; F415-M418 HydrophobicContact CD2-CE 3.6Å; F415-M418 HydrophobicContact CE2-CE 3.69Å; F415-M418 WeakPolarHBondContact O-CB 3.25Å; F415-M418 PolarHBondContact O-N 2.84Å; M418-L420 VanDerWaalsContact C-N 3.34Å; M418-L420 PolarHBondContact O-N 2.64Å; M418-T421 WeakPolarHBondContact CA-OG1 3.33Å; M418-T421 PolarHBondContact O-N 2.93Å; M418-T421 PolarHBondContact O-OG1 2.9Å; M418-L422 HydrophobicContact CG-CD1 3.96Å; M418-L422 HydrophobicContact CG-CG 4.45Å; M418-L422 WeakPolarHBondContact O-CB 2.91Å; M418-L422 WeakPolarHBondContact O-CG 2.99Å; M418-L422 PolarHBondContact O-N 3.35Å
419	L	93.6	Very high	94.1	Very high	1 Å²	1	19.8 Å²	19.8	1%	0.005	10%	0.1	C	C	.	.	H	α-helix	trans	-63.1	-41.2	179.1	-66.7	169.3	0	0	0	112.5	L84 V394 F415 F416 G423	L84-L419 HydrophobicContact CD2-CD2 4.26Å; L84-L419 HydrophobicContact CG-CD2 4.34Å; V394-L419 HydrophobicContact CG1-CD1 3.21Å; V394-L419 HydrophobicContact CG1-CD2 3.72Å; V394-L419 HydrophobicContact CG1-CG 4.09Å; V394-L419 HydrophobicContact CG2-CD2 4.47Å; F415-L419 HydrophobicContact CD1-CD1 3.92Å; F415-L419 HydrophobicContact CE1-CD1 3.47Å; F415-L419 VanDerWaalsContact CE1-CD1 3.47Å; F415-L419 HydrophobicContact CE1-CG 4.37Å; F415-L419 HydrophobicContact CZ-CD1 3.81Å; F415-L419 HydrophobicContact CZ-CD2 4.48Å; F415-L419 HydrophobicContact CZ-CG 4.34Å; F415-L419 WeakPolarHBondContact O-CG 3.41Å; F415-L419 PolarHBondContact O-N 2.74Å; F416-L419 HydrophobicContact CD1-CD1 3.68Å; F416-L419 HydrophobicContact CE1-CD1 3.99Å; F416-L419 PolarHBondContact O-N 3.3Å; L419-G423 PolarHBondContact O-N 3.44Å
420	L	95	Very high	94.1	Very high	24 Å²	24	18.6 Å²	18.6	13%	0.126	10%	0.095	C	C	.	.	H	α-helix	trans	-63.8	-42.8	177.2	179.6	141.1	0	0	0	111.5	L168 F416 I417 M418 G423 I424	L168-L420 HydrophobicContact CB-CD1 3.95Å; L168-L420 HydrophobicContact CD1-CD1 3.72Å; L168-L420 HydrophobicContact CG-CD1 4.36Å; F416-L420 VanDerWaalsContact O-CB 3.28Å; F416-L420 WeakPolarHBondContact O-CB 3.36Å; F416-L420 PolarHBondContact O-N 3.33Å; I417-L420 PolarHBondContact O-N 3.37Å; M418-L420 VanDerWaalsContact C-N 3.34Å; M418-L420 PolarHBondContact O-N 2.64Å; L420-G423 PolarHBondContact O-N 3.42Å; L420-I424 HydrophobicContact CD2-CD1 3.38Å; L420-I424 HydrophobicContact CG-CD1 3.78Å; L420-I424 WeakPolarHBondContact O-CB 3.33Å; L420-I424 WeakPolarHBondContact O-CD1 2.91Å; L420-I424 WeakPolarHBondContact O-CG1 3.47Å; L420-I424 PolarHBondContact O-N 3.12Å
421	T	94.6	Very high	94.2	Very high	8 Å²	8	13.1 Å²	13.1	5%	0.049	7%	0.072	C	C	.	.	H	α-helix	trans	-68.6	-43.3	179	46.8	0	0	0	0	112.5	T273 M276 I417 M418 G423 I424 D425	T273-T421 HydrophobicContact CG2-CG2 4.12Å; M276-T421 HydrophobicContact CB-CG2 4.41Å; I417-T421 HydrophobicContact CG2-CG2 4.37Å; I417-T421 WeakPolarHBondContact O-CB 3.29Å; I417-T421 WeakPolarHBondContact O-CG2 3.37Å; I417-T421 PolarHBondContact O-N 3.07Å; I417-T421 PolarHBondContact O-OG1 3.01Å; M418-T421 WeakPolarHBondContact CA-OG1 3.33Å; M418-T421 PolarHBondContact O-N 2.93Å; M418-T421 PolarHBondContact O-OG1 2.9Å; T421-G423 VanDerWaalsContact C-N 3.35Å; T421-G423 PolarHBondContact O-N 3.41Å; T421-I424 PolarHBondContact O-N 3.41Å; T421-D425 PolarHBondContact O-N 3.02Å
422	L	93.9	Very high	94.4	Very high	5 Å²	5	11.4 Å²	11.4	3%	0.026	7%	0.065	C	C	.	.	H	α-helix	trans	-57.7	-45.7	171.6	-73.7	172.2	0	0	0	111.8	V82 L84 V87 P277 M418 S426	V82-L422 HydrophobicContact CG1-CD2 3.86Å; V82-L422 WeakPolarHBondContact O-CD2 3.31Å; L84-L422 HydrophobicContact CD1-CB 4.09Å; V87-L422 HydrophobicContact CG2-CD1 3.8Å; P277-L422 HydrophobicContact CB-CD1 4.31Å; P277-L422 HydrophobicContact CB-CD2 3.58Å; P277-L422 HydrophobicContact CB-CG 3.79Å; P277-L422 HydrophobicContact CG-CD2 3.56Å; P277-L422 HydrophobicContact CG-CG 3.62Å; M418-L422 HydrophobicContact CG-CD1 3.96Å; M418-L422 HydrophobicContact CG-CG 4.45Å; M418-L422 WeakPolarHBondContact O-CB 2.91Å; M418-L422 WeakPolarHBondContact O-CG 2.99Å; M418-L422 PolarHBondContact O-N 3.35Å; L422-S426 PolarHBondContact O-OG 3.49Å; L422-S426 VanDerWaalsContact O-OG 3.11Å
423	G	94.7	Very high	94.4	Very high	0 Å²	0	11.4 Å²	11.4	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-66.5	-42.8	-179.5	0	0	0	0	0	113.3	Y160 I164 L419 L420 T421 D425 S427	Y160-G423 WeakPolarHBondContact CE1-O 3.37Å; I164-G423 VanDerWaalsContact CD1-C 3.41Å; I164-G423 VanDerWaalsContact CD1-O 3.26Å; I164-G423 WeakPolarHBondContact CD1-O 3.05Å; L419-G423 PolarHBondContact O-N 3.44Å; L420-G423 PolarHBondContact O-N 3.42Å; T421-G423 VanDerWaalsContact C-N 3.35Å; T421-G423 PolarHBondContact O-N 3.41Å; G423-D425 PolarHBondContact O-N 3.32Å; G423-S427 WeakPolarHBondContact O-CB 3.07Å; G423-S427 PolarHBondContact O-N 2.97Å
424	I	95.4	Very high	94.5	Very high	5 Å²	5	9.5 Å²	9.5	3%	0.026	6%	0.056	C	C	.	.	H	α-helix	trans	-62.9	-43.4	-177.3	-74.8	168.3	0	0	0	111.4	I164 I254 L255 T273 L420 T421 S427 M428	I164-I424 HydrophobicContact CG2-CG1 4.07Å; I254-I424 HydrophobicContact CG2-CD1 4Å; I254-I424 HydrophobicContact CG2-CG2 4.49Å; L255-I424 HydrophobicContact CD2-CG2 4.34Å; T273-I424 HydrophobicContact CG2-CG2 4.2Å; L420-I424 HydrophobicContact CD2-CD1 3.38Å; L420-I424 HydrophobicContact CG-CD1 3.78Å; L420-I424 WeakPolarHBondContact O-CB 3.33Å; L420-I424 WeakPolarHBondContact O-CD1 2.91Å; L420-I424 WeakPolarHBondContact O-CG1 3.47Å; L420-I424 PolarHBondContact O-N 3.12Å; T421-I424 PolarHBondContact O-N 3.41Å; I424-S427 PolarHBondContact O-N 3.44Å; I424-M428 HydrophobicContact CG2-CG 4.17Å; I424-M428 HydrophobicContact CG2-SD 3.6Å; I424-M428 WeakPolarHBondContact O-CB 3.16Å; I424-M428 VanDerWaalsContact O-CG 3.23Å; I424-M428 WeakPolarHBondContact O-CG 3.27Å; I424-M428 PolarHBondContact O-N 3.05Å
425	D	94.4	Very high	94.6	Very high	7 Å²	7	8 Å²	8	4%	0.037	5%	0.046	C	C	.	.	H	α-helix	trans	-64.4	-46.5	-178.3	-83.5	-15.6	0	0	0	112.7	G79 T273 A274 T421 G423 S427 M428 G429	G79-D425 VanDerWaalsContact O-CB 3.32Å; G79-D425 WeakPolarHBondContact O-CB 2.87Å; T273-D425 WeakPolarHBondContact CB-OD1 3.33Å; T273-D425 VanDerWaalsContact CB-OD2 3.25Å; T273-D425 WeakPolarHBondContact CB-OD2 3.25Å; T273-D425 PolarHBondContact OG1-OD1 3.16Å; T273-D425 PolarHBondContact OG1-OD2 3.1Å; T273-D425 VanDerWaalsContact OG1-OD2 3.12Å; A274-D425 VanDerWaalsContact CA-OD2 3.22Å; A274-D425 WeakPolarHBondContact CA-OD2 3.26Å; A274-D425 WeakPolarHBondContact CB-OD2 3.29Å; A274-D425 PolarHBondContact N-OD2 3.49Å; T421-D425 PolarHBondContact O-N 3.02Å; G423-D425 PolarHBondContact O-N 3.32Å; D425-S427 VanDerWaalsContact C-N 3.33Å; D425-S427 PolarHBondContact O-N 3.28Å; D425-M428 WeakPolarHBondContact O-CB 3.36Å; D425-M428 PolarHBondContact O-N 3.42Å; D425-G429 PolarHBondContact O-N 3.05Å
426	S	94.4	Very high	94.6	Very high	11 Å²	11	7.9 Å²	7.9	8%	0.077	5%	0.046	C	C	.	.	H	α-helix	trans	-63.3	-41.3	177.9	-40.6	0	0	0	0	111.4	D83 Y160 L422 G429 G430	D83-S426 WeakPolarHBondContact CB-OG 3.43Å; Y160-S426 PolarHBondContact OH-OG 3.11Å; L422-S426 PolarHBondContact O-OG 3.49Å; L422-S426 VanDerWaalsContact O-OG 3.11Å; S426-G429 PolarHBondContact O-N 3.03Å; S426-G430 PolarHBondContact O-N 3.36Å
427	S	95.2	Very high	94.4	Very high	7 Å²	7	7.9 Å²	7.9	5%	0.049	5%	0.046	C	C	.	.	H	α-helix	trans	-68	-34.9	176.5	-174.6	0	0	0	0	112.7	N161 L255 G423 I424 D425 G429 M431	N161-S427 PolarHBondContact OD1-OG 2.86Å; L255-S427 WeakPolarHBondContact CD1-OG 3.41Å; G423-S427 WeakPolarHBondContact O-CB 3.07Å; G423-S427 PolarHBondContact O-N 2.97Å; I424-S427 PolarHBondContact O-N 3.44Å; D425-S427 VanDerWaalsContact C-N 3.33Å; D425-S427 PolarHBondContact O-N 3.28Å; S427-G429 VanDerWaalsContact C-N 3.34Å; S427-M431 WeakPolarHBondContact O-CB 3.39Å; S427-M431 PolarHBondContact O-N 3.4Å
428	M	94.9	Very high	94.4	Very high	2 Å²	2	6.6 Å²	6.6	1%	0.01	4%	0.04	C	C	.	.	H	α-helix	trans	-61.8	-44.2	173.4	-80.1	172.5	44.8	0	0	110.9	L255 S258 L259 S266 V269 V270 I424 D425 E432	L255-M428 HydrophobicContact CD2-CG 3.76Å; S258-M428 VanDerWaalsContact CB-SD 3.52Å; L259-M428 HydrophobicContact CD2-CB 4.18Å; L259-M428 HydrophobicContact CD2-CG 4.34Å; L259-M428 HydrophobicContact CG-CG 4.44Å; S266-M428 WeakPolarHBondContact OG-CE 3.26Å; V269-M428 HydrophobicContact CB-CE 4.26Å; V269-M428 HydrophobicContact CG1-CE 4.39Å; V269-M428 HydrophobicContact CG1-SD 4.13Å; V270-M428 HydrophobicContact CG1-CE 4.15Å; I424-M428 HydrophobicContact CG2-CG 4.17Å; I424-M428 HydrophobicContact CG2-SD 3.6Å; I424-M428 WeakPolarHBondContact O-CB 3.16Å; I424-M428 VanDerWaalsContact O-CG 3.23Å; I424-M428 WeakPolarHBondContact O-CG 3.27Å; I424-M428 PolarHBondContact O-N 3.05Å; D425-M428 WeakPolarHBondContact O-CB 3.36Å; D425-M428 PolarHBondContact O-N 3.42Å; M428-E432 VanDerWaalsContact O-CB 3.24Å; M428-E432 WeakPolarHBondContact O-CB 3.34Å; M428-E432 PolarHBondContact O-N 3.03Å
429	G	94.3	Very high	94.3	Very high	0 Å²	0	6.8 Å²	6.8	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-60.9	-52.3	175.4	0	0	0	0	0	112.8	V332 F336 D425 S426 S427 M431 E432 A433	V332-G429 WeakPolarHBondContact CG2-O 3.32Å; F336-G429 VanDerWaalsContact CZ-CA 3.49Å; D425-G429 PolarHBondContact O-N 3.05Å; S426-G429 PolarHBondContact O-N 3.03Å; S427-G429 VanDerWaalsContact C-N 3.34Å; G429-M431 PolarHBondContact O-N 3.22Å; G429-E432 PolarHBondContact O-N 2.79Å; G429-A433 PolarHBondContact O-N 2.98Å
430	G	94.3	Very high	94	Very high	13 Å²	13	8.6 Å²	8.6	13%	0.134	5%	0.051	C	C	.	.	H	α-helix	trans	-57.8	-45.5	179.1	0	0	0	0	0	112.9	S426 A433 V434	S426-G430 PolarHBondContact O-N 3.36Å; G430-A433 WeakPolarHBondContact O-CB 3.29Å; G430-A433 PolarHBondContact O-N 3.28Å; G430-V434 PolarHBondContact O-N 3.42Å
431	M	94.8	Very high	93.7	Very high	13 Å²	13	9.7 Å²	9.7	6%	0.064	6%	0.056	C	C	.	.	H	α-helix	trans	-69.2	-36.5	178.3	-175.9	172.5	-82	0	0	112.1	L259 S427 G429 A433 V434 I435 T456 A457 T460	L259-M431 HydrophobicContact CD1-CB 3.69Å; L259-M431 HydrophobicContact CD1-CG 3.62Å; L259-M431 HydrophobicContact CD1-SD 3.7Å; S427-M431 WeakPolarHBondContact O-CB 3.39Å; S427-M431 PolarHBondContact O-N 3.4Å; G429-M431 PolarHBondContact O-N 3.22Å; M431-A433 VanDerWaalsContact C-N 3.31Å; M431-A433 PolarHBondContact O-N 3.38Å; M431-V434 PolarHBondContact O-N 3.27Å; M431-I435 HydrophobicContact CG-CD1 3.72Å; M431-I435 HydrophobicContact CG-CG1 4.34Å; M431-I435 WeakPolarHBondContact O-CD1 3.33Å; M431-I435 VanDerWaalsContact O-CG1 3.26Å; M431-I435 WeakPolarHBondContact O-CG1 3.14Å; M431-I435 PolarHBondContact O-N 2.9Å; M431-I435 HydrophobicContact SD-CD1 4.48Å; M431-T456 HydrophobicContact CE-CG2 4.36Å; M431-T456 HydrophobicContact CG-CG2 4.35Å; M431-A457 HydrophobicContact CE-CB 3.96Å; M431-A457 HydrophobicContact SD-CB 4.11Å; M431-T460 HydrophobicContact CE-CG2 4.27Å; M431-T460 WeakPolarHBondContact CE-OG1 3.07Å
432	E	95.1	Very high	93.4	Very high	0 Å²	0	14 Å²	14	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-64.4	-34.3	174.9	-175.5	66	-170	0	0	112.1	L259 F336 M428 G429 I435 T436 R449	L259-E432 HydrophobicContact CD2-CB 4.23Å; F336-E432 HydrophobicContact CD1-CG 4.32Å; F336-E432 HydrophobicContact CE1-CB 4.06Å; F336-E432 HydrophobicContact CE1-CG 3.9Å; M428-E432 VanDerWaalsContact O-CB 3.24Å; M428-E432 WeakPolarHBondContact O-CB 3.34Å; M428-E432 PolarHBondContact O-N 3.03Å; G429-E432 PolarHBondContact O-N 2.79Å; E432-I435 PolarHBondContact O-N 3.37Å; E432-T436 WeakPolarHBondContact O-CB 3.11Å; E432-T436 PolarHBondContact O-N 3.32Å; E432-T436 PolarHBondContact O-OG1 2.87Å; E432-T436 PolarHBondContact OE1-OG1 3.5Å; E432-R449 IonicContact OE1-CZ 3.55Å; E432-R449 IonicContact OE1-NH1 2.57Å; E432-R449 IonicContact OE1-NH2 3.25Å; E432-R449 PolarHBondContact OE1-NH2 3.23Å; E432-R449 IonicContact OE2-NH2 3.92Å; E432-R449 PolarHBondContact OE2-NH2 3.05Å
433	A	94.5	Very high	93	Very high	1 Å²	1	22.2 Å²	22.2	1%	0.008	11%	0.11	C	C	.	.	H	α-helix	trans	-62.9	-44.7	174.1	0	0	0	0	0	112.1	V332 A335 G429 G430 M431 G437	V332-A433 HydrophobicContact CB-CB 4.33Å; V332-A433 HydrophobicContact CG2-CB 3.68Å; A335-A433 HydrophobicContact CB-CB 4.42Å; G429-A433 PolarHBondContact O-N 2.98Å; G430-A433 WeakPolarHBondContact O-CB 3.29Å; G430-A433 PolarHBondContact O-N 3.28Å; M431-A433 VanDerWaalsContact C-N 3.31Å; M431-A433 PolarHBondContact O-N 3.38Å; A433-G437 PolarHBondContact O-N 2.88Å
434	V	95.4	Very high	92.7	Very high	6 Å²	6	28.2 Å²	28.2	4%	0.036	14%	0.141	C	C	.	.	H	α-helix	trans	-62.6	-49.3	175.4	176.7	0	0	0	0	110.6	I150 A153 L154 G430 M431 L438 T456	I150-V434 HydrophobicContact CG2-CB 4.41Å; I150-V434 HydrophobicContact CG2-CG1 4.1Å; I150-V434 HydrophobicContact CG2-CG2 4.27Å; A153-V434 HydrophobicContact CB-CG2 3.86Å; L154-V434 HydrophobicContact CB-CG2 4.32Å; G430-V434 PolarHBondContact O-N 3.42Å; M431-V434 PolarHBondContact O-N 3.27Å; V434-L438 HydrophobicContact CG1-CD1 4.03Å; V434-L438 WeakPolarHBondContact O-CG 3.45Å; V434-L438 PolarHBondContact O-N 3.47Å; V434-L438 VanDerWaalsContact O-N 3.16Å; V434-T456 HydrophobicContact CG1-CG2 4.09Å
435	I	94.4	Very high	92.4	Very high	0 Å²	0	30 Å²	30	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-61.4	-51	-178.5	-67.9	163.4	0	0	0	110	L259 M431 E432 T439 R449 F452 T453	L259-I435 HydrophobicContact CD1-CD1 4.28Å; M431-I435 HydrophobicContact CG-CD1 3.72Å; M431-I435 HydrophobicContact CG-CG1 4.34Å; M431-I435 WeakPolarHBondContact O-CD1 3.33Å; M431-I435 VanDerWaalsContact O-CG1 3.26Å; M431-I435 WeakPolarHBondContact O-CG1 3.14Å; M431-I435 PolarHBondContact O-N 2.9Å; M431-I435 HydrophobicContact SD-CD1 4.48Å; E432-I435 PolarHBondContact O-N 3.37Å; I435-T439 WeakPolarHBondContact O-CB 3.22Å; I435-T439 PolarHBondContact O-N 2.87Å; I435-T439 PolarHBondContact O-OG1 3.47Å; I435-R449 HydrophobicContact CG2-CG 4.37Å; I435-F452 HydrophobicContact CB-CE1 4.48Å; I435-F452 HydrophobicContact CG2-CD1 4.23Å; I435-F452 HydrophobicContact CG2-CE1 4.39Å; I435-T453 HydrophobicContact CD1-CG2 3.71Å
436	T	93.6	Very high	92	Very high	0 Å²	0	35.9 Å²	35.9	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-66.1	-45.1	-176.7	-59.3	0	0	0	0	111.6	A335 Y339 E432 L438 T439 D440	A335-T436 HydrophobicContact CB-CG2 4.13Å; Y339-T436 HydrophobicContact CE2-CG2 4.09Å; Y339-T436 WeakPolarHBondContact OH-CG2 3.28Å; Y339-T436 PolarHBondContact OH-OG1 3.43Å; E432-T436 WeakPolarHBondContact O-CB 3.11Å; E432-T436 PolarHBondContact O-N 3.32Å; E432-T436 PolarHBondContact O-OG1 2.87Å; E432-T436 PolarHBondContact OE1-OG1 3.5Å; T436-L438 VanDerWaalsContact C-N 3.33Å; T436-L438 PolarHBondContact O-N 3.21Å; T436-T439 PolarHBondContact O-N 2.85Å; T436-D440 WeakPolarHBondContact O-CB 3.44Å; T436-D440 PolarHBondContact O-N 3.4Å; T436-D440 VanDerWaalsContact O-N 3.08Å
437	G	92.2	Very high	91.6	Very high	0 Å²	0	45.1 Å²	45.1	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-59.7	-39.7	179.8	0	0	0	0	0	113.4	A433	A433-G437 PolarHBondContact O-N 2.88Å
438	L	93.6	Very high	91.4	Very high	36 Å²	36	48.1 Å²	48.1	19%	0.188	22%	0.224	C	C	.	.	H	α-helix	trans	-84.7	-34.8	178.7	-65.8	173.9	0	0	0	112.8	Y147 I150 V434 T436 D440 D441 F442 L445 F452	Y147-L438 HydrophobicContact CE1-CD2 4.42Å; I150-L438 HydrophobicContact CD1-CD2 4.37Å; I150-L438 HydrophobicContact CD1-CG 4.42Å; I150-L438 HydrophobicContact CG2-CD1 4.24Å; I150-L438 HydrophobicContact CG2-CG 4.23Å; V434-L438 HydrophobicContact CG1-CD1 4.03Å; V434-L438 WeakPolarHBondContact O-CG 3.45Å; V434-L438 PolarHBondContact O-N 3.47Å; V434-L438 VanDerWaalsContact O-N 3.16Å; T436-L438 VanDerWaalsContact C-N 3.33Å; T436-L438 PolarHBondContact O-N 3.21Å; L438-D440 VanDerWaalsContact C-N 3.3Å; L438-D440 PolarHBondContact O-N 3.26Å; L438-D441 PolarHBondContact O-N 3.38Å; L438-F442 HydrophobicContact CD2-CE2 4.29Å; L438-F442 WeakPolarHBondContact O-CD2 3.5Å; L438-F442 PolarHBondContact O-N 3.39Å; L438-F442 VanDerWaalsContact O-N 3.07Å; L438-L445 HydrophobicContact CB-CD1 4.11Å; L438-F452 HydrophobicContact CB-CE1 3.97Å; L438-F452 HydrophobicContact CB-CZ 3.8Å; L438-F452 HydrophobicContact CD1-CZ 3.72Å; L438-F452 HydrophobicContact CG-CZ 4.41Å
439	T	91.7	Very high	91.2	Very high	4 Å²	4	49.9 Å²	49.9	3%	0.025	23%	0.231	C	C	.	.	H	α-helix	trans	-65.6	-34.5	179.8	-65.6	0	0	0	0	112.3	I435 T436 D441 K446	I435-T439 WeakPolarHBondContact O-CB 3.22Å; I435-T439 PolarHBondContact O-N 2.87Å; I435-T439 PolarHBondContact O-OG1 3.47Å; T436-T439 PolarHBondContact O-N 2.85Å; T439-D441 VanDerWaalsContact C-N 3.33Å; T439-K446 HydrophobicContact CG2-CB 3.59Å; T439-K446 HydrophobicContact CG2-CG 3.81Å
440	D	88.6	Confident	91.1	Very high	39 Å²	39	55.8 Å²	55.8	21%	0.209	26%	0.256	C	S	.	.	H	α-helix	trans	-73.3	-26.8	178.7	-74.8	-16.2	0	0	0	112.7	R64 G131 T134 T436 L438	R64-D440 IonicContact CZ-OD2 3.45Å; R64-D440 VanDerWaalsContact CZ-OD2 3.28Å; R64-D440 VanDerWaalsContact NH1-CG 3.35Å; R64-D440 IonicContact NH1-OD1 3.16Å; R64-D440 PolarHBondContact NH1-OD1 3.15Å; R64-D440 IonicContact NH1-OD2 2.76Å; R64-D440 PolarHBondContact NH1-OD2 3.14Å; R64-D440 IonicContact NH2-OD1 3.11Å; R64-D440 IonicContact NH2-OD2 3.71Å; R64-D440 PolarHBondContact NH2-OD2 2.6Å; G131-D440 PolarHBondContact N-OD2 3.15Å; T134-D440 HydrophobicContact CG2-CB 4.01Å; T134-D440 WeakPolarHBondContact OG1-CB 3.43Å; T436-D440 WeakPolarHBondContact O-CB 3.44Å; T436-D440 PolarHBondContact O-N 3.4Å; T436-D440 VanDerWaalsContact O-N 3.08Å; L438-D440 VanDerWaalsContact C-N 3.3Å; L438-D440 PolarHBondContact O-N 3.26Å
441	D	87.1	Confident	91.1	Very high	46 Å²	46	60.5 Å²	60.5	25%	0.246	28%	0.278	C	S	.	.	H	α-helix	trans	-85.5	-36.4	-179.9	-154.5	40.6	0	0	0	112.3	T134 K143 Y147 L438 T439	T134-D441 HydrophobicContact CG2-CB 3.76Å; K143-D441 VanDerWaalsContact NZ-CG 3.34Å; K143-D441 IonicContact NZ-OD1 3.31Å; K143-D441 PolarHBondContact NZ-OD1 2.75Å; K143-D441 IonicContact NZ-OD2 2.73Å; K143-D441 PolarHBondContact NZ-OD2 2.94Å; Y147-D441 PolarHBondContact OH-OD2 2.71Å; L438-D441 PolarHBondContact O-N 3.38Å; T439-D441 VanDerWaalsContact C-N 3.33Å
442	F	89.4	Confident	91.1	Very high	100 Å²	100	61.2 Å²	61.2	44%	0.439	28%	0.281	S	S	.	.			trans	-113.3	109.4	-176.6	-58.8	-77.3	0	0	0	112.6	L438 I444 L445 K446	L438-F442 HydrophobicContact CD2-CE2 4.29Å; L438-F442 WeakPolarHBondContact O-CD2 3.5Å; L438-F442 PolarHBondContact O-N 3.39Å; L438-F442 VanDerWaalsContact O-N 3.07Å; F442-I444 PolarHBondContact O-N 3.12Å; F442-I444 VanDerWaalsContact O-N 3.1Å; F442-L445 HydrophobicContact CB-CB 4.25Å; F442-L445 HydrophobicContact CB-CD1 3.64Å; F442-L445 HydrophobicContact CB-CG 3.86Å; F442-L445 HydrophobicContact CD2-CD1 3.68Å; F442-L445 HydrophobicContact CG-CD1 3.98Å; F442-L445 WeakPolarHBondContact O-CB 3.1Å; F442-L445 PolarHBondContact O-N 3.3Å; F442-K446 PolarHBondContact O-N 2.95Å
443	K	85.3	Confident	91	Very high	176 Å²	176	61.2 Å²	61.2	77%	0.765	28%	0.281	S	S	*	.	H	α-helix	trans	-54.5	-33.2	179	-66	-172.7	179.8	-171.6	0	113.9	K446 R447	K443-K446 PolarHBondContact O-N 3.37Å; K443-R447 PolarHBondContact O-N 3.05Å; K443-R447 VanDerWaalsContact O-N 3.11Å
444	I	88.3	Confident	91	Very high	126 Å²	126	66 Å²	66	65%	0.646	30%	0.302	S	S	*	.	H	α-helix	trans	-64.7	-43.5	178.9	-62.2	168.9	0	0	0	110.8	F442 K446 R447 N448	F442-I444 PolarHBondContact O-N 3.12Å; F442-I444 VanDerWaalsContact O-N 3.1Å; I444-K446 VanDerWaalsContact C-N 3.33Å; I444-R447 PolarHBondContact O-N 3.39Å; I444-N448 PolarHBondContact O-N 3.47Å
445	L	88.6	Confident	91	Very high	43 Å²	43	68.2 Å²	68.2	23%	0.225	32%	0.32	C	S	.	.	H	α-helix	trans	-66	-38.1	178	-62.2	174	0	0	0	110.7	L438 F442 N448 R449 F452	L438-L445 HydrophobicContact CB-CD1 4.11Å; F442-L445 HydrophobicContact CB-CB 4.25Å; F442-L445 HydrophobicContact CB-CD1 3.64Å; F442-L445 HydrophobicContact CB-CG 3.86Å; F442-L445 HydrophobicContact CD2-CD1 3.68Å; F442-L445 HydrophobicContact CG-CD1 3.98Å; F442-L445 WeakPolarHBondContact O-CB 3.1Å; F442-L445 PolarHBondContact O-N 3.3Å; L445-N448 CarbonylContact O-C 3.41Å; L445-N448 VanDerWaalsContact O-C 3.24Å; L445-N448 PolarHBondContact O-N 3.09Å; L445-R449 WeakPolarHBondContact O-CA 3.41Å; L445-R449 PolarHBondContact O-N 2.95Å; L445-F452 HydrophobicContact CB-CD1 4.25Å; L445-F452 HydrophobicContact CB-CG 4.4Å; L445-F452 HydrophobicContact CD1-CE1 4.33Å; L445-F452 HydrophobicContact CD1-CE2 4.28Å; L445-F452 HydrophobicContact CD1-CZ 4.12Å; L445-F452 HydrophobicContact CD2-CB 4.25Å; L445-F452 HydrophobicContact CD2-CD1 4.36Å; L445-F452 HydrophobicContact CD2-CD2 3.57Å; L445-F452 HydrophobicContact CD2-CE2 3.92Å; L445-F452 HydrophobicContact CD2-CG 3.81Å; L445-F452 HydrophobicContact CD2-CZ 4.46Å
446	K	85.6	Confident	91	Very high	131 Å²	131	69 Å²	69	57%	0.57	33%	0.326	S	S	*	.	H	α-helix	trans	-61	-44.8	175.3	-167	171.7	-179.8	173.3	0	113.8	T439 F442 K443 I444 N448	T439-K446 HydrophobicContact CG2-CB 3.59Å; T439-K446 HydrophobicContact CG2-CG 3.81Å; F442-K446 PolarHBondContact O-N 2.95Å; K443-K446 PolarHBondContact O-N 3.37Å; I444-K446 VanDerWaalsContact C-N 3.33Å; K446-N448 VanDerWaalsContact C-N 3.26Å; K446-N448 PolarHBondContact O-N 3.28Å
447	R	87.8	Confident	91	Very high	205 Å²	205	69.1 Å²	69.1	77%	0.774	33%	0.326	S	S	*	.	H	α-helix	trans	-63.2	-36.4	177.1	-169.3	171.8	68.4	179.8	0.8	111.8	K443 I444	K443-R447 PolarHBondContact O-N 3.05Å; K443-R447 VanDerWaalsContact O-N 3.11Å; I444-R447 PolarHBondContact O-N 3.39Å
448	N	90.8	Very high	91.2	Very high	70 Å²	70	73.7 Å²	73.7	37%	0.374	35%	0.346	S	S	.	.	T	Hydrogen-bonded Turn	trans	-109.5	34.9	-174.9	-64.5	-10.6	0	0	0	112.7	I444 L445 K446 K450 L451 F452	I444-N448 PolarHBondContact O-N 3.47Å; L445-N448 CarbonylContact O-C 3.41Å; L445-N448 VanDerWaalsContact O-C 3.24Å; L445-N448 PolarHBondContact O-N 3.09Å; K446-N448 VanDerWaalsContact C-N 3.26Å; K446-N448 PolarHBondContact O-N 3.28Å; N448-K450 PolarHBondContact O-N 2.92Å; N448-K450 VanDerWaalsContact O-N 3.08Å; N448-L451 HydrophobicContact CB-CB 4.38Å; N448-L451 PolarHBondContact O-N 2.94Å; N448-F452 PolarHBondContact O-N 3.27Å
449	R	90.2	Very high	91.2	Very high	39 Å²	39	73.3 Å²	73.3	15%	0.147	35%	0.351	C	S	.	.	H	α-helix	trans	-50.5	-40.9	-172.7	-179.1	178.1	174.2	125.5	0.6	113.8	Y339 E432 I435 L445 F452 T453	Y339-R449 PolarHBondContact OH-NH1 3.25Å; Y339-R449 VanDerWaalsContact OH-NH1 3.12Å; E432-R449 IonicContact OE1-CZ 3.55Å; E432-R449 IonicContact OE1-NH1 2.57Å; E432-R449 IonicContact OE1-NH2 3.25Å; E432-R449 PolarHBondContact OE1-NH2 3.23Å; E432-R449 IonicContact OE2-NH2 3.92Å; E432-R449 PolarHBondContact OE2-NH2 3.05Å; I435-R449 HydrophobicContact CG2-CG 4.37Å; L445-R449 WeakPolarHBondContact O-CA 3.41Å; L445-R449 PolarHBondContact O-N 2.95Å; R449-F452 PolarHBondContact O-N 3.47Å; R449-T453 WeakPolarHBondContact O-CB 3.43Å; R449-T453 PolarHBondContact O-N 3.42Å; R449-T453 PolarHBondContact O-OG1 3.39Å
450	K	92.9	Very high	91.3	Very high	123 Å²	123	73.3 Å²	73.3	54%	0.535	35%	0.351	S	S	.	.	H	α-helix	trans	-61.4	-46.9	178.7	-66.6	179.9	-177.9	175.9	0	112	N448 F452 T453 F454	N448-K450 PolarHBondContact O-N 2.92Å; N448-K450 VanDerWaalsContact O-N 3.08Å; K450-F452 VanDerWaalsContact C-N 3.32Å; K450-T453 PolarHBondContact O-N 3.46Å; K450-F454 PolarHBondContact O-N 3.17Å
451	L	93.2	Very high	91.6	Very high	113 Å²	113	72.8 Å²	72.8	59%	0.592	35%	0.347	S	S	*	.	H	α-helix	trans	-66.6	-38.2	177.7	-176.2	64.9	0	0	0	111	N448 F454 A455	N448-L451 HydrophobicContact CB-CB 4.38Å; N448-L451 PolarHBondContact O-N 2.94Å; L451-F454 WeakPolarHBondContact O-CB 3.4Å; L451-F454 PolarHBondContact O-N 3.39Å; L451-A455 WeakPolarHBondContact O-CB 3.28Å; L451-A455 PolarHBondContact O-N 2.89Å
452	F	94.4	Very high	92	Very high	28 Å²	28	74.4 Å²	74.4	12%	0.123	36%	0.356	C	S	.	.	H	α-helix	trans	-65.5	-43.8	175.8	-179.8	-130.6	0	0	0	112.2	I435 L438 L445 N448 R449 K450 F454 A455 T456	I435-F452 HydrophobicContact CB-CE1 4.48Å; I435-F452 HydrophobicContact CG2-CD1 4.23Å; I435-F452 HydrophobicContact CG2-CE1 4.39Å; L438-F452 HydrophobicContact CB-CE1 3.97Å; L438-F452 HydrophobicContact CB-CZ 3.8Å; L438-F452 HydrophobicContact CD1-CZ 3.72Å; L438-F452 HydrophobicContact CG-CZ 4.41Å; L445-F452 HydrophobicContact CB-CD1 4.25Å; L445-F452 HydrophobicContact CB-CG 4.4Å; L445-F452 HydrophobicContact CD1-CE1 4.33Å; L445-F452 HydrophobicContact CD1-CE2 4.28Å; L445-F452 HydrophobicContact CD1-CZ 4.12Å; L445-F452 HydrophobicContact CD2-CB 4.25Å; L445-F452 HydrophobicContact CD2-CD1 4.36Å; L445-F452 HydrophobicContact CD2-CD2 3.57Å; L445-F452 HydrophobicContact CD2-CE2 3.92Å; L445-F452 HydrophobicContact CD2-CG 3.81Å; L445-F452 HydrophobicContact CD2-CZ 4.46Å; N448-F452 PolarHBondContact O-N 3.27Å; R449-F452 PolarHBondContact O-N 3.47Å; K450-F452 VanDerWaalsContact C-N 3.32Å; F452-F454 VanDerWaalsContact C-N 3.29Å; F452-F454 PolarHBondContact O-N 3.44Å; F452-A455 PolarHBondContact O-N 2.96Å; F452-A455 VanDerWaalsContact O-N 3.1Å; F452-T456 PolarHBondContact O-N 3.44Å; F452-T456 PolarHBondContact O-OG1 3.19Å; F452-T456 VanDerWaalsContact O-OG1 3.12Å
453	T	93.9	Very high	92.3	Very high	0 Å²	0	72.1 Å²	72.1	0%	0	35%	0.349	C	S	.	.	H	α-helix	trans	-57.8	-44.3	174.3	-54.7	0	0	0	0	110.6	Y256 L259 I435 R449 K450 T456 A457	Y256-T453 HydrophobicContact CD2-CG2 4Å; Y256-T453 HydrophobicContact CE2-CG2 4.38Å; L259-T453 HydrophobicContact CB-CG2 3.97Å; I435-T453 HydrophobicContact CD1-CG2 3.71Å; R449-T453 WeakPolarHBondContact O-CB 3.43Å; R449-T453 PolarHBondContact O-N 3.42Å; R449-T453 PolarHBondContact O-OG1 3.39Å; K450-T453 PolarHBondContact O-N 3.46Å; T453-T456 PolarHBondContact O-N 3.05Å; T453-A457 VanDerWaalsContact O-CB 3.26Å; T453-A457 WeakPolarHBondContact O-CB 3.23Å; T453-A457 PolarHBondContact O-N 2.89Å
454	F	94.9	Very high	92.8	Very high	102 Å²	102	63.7 Å²	63.7	45%	0.447	31%	0.313	S	S	.	.	H	α-helix	trans	-61.2	-46.2	173.8	179.6	-101	0	0	0	111.9	Y256 K450 L451 F452 T456 A457 F458	Y256-F454 HydrophobicContact CD2-CB 4.03Å; Y256-F454 HydrophobicContact CD2-CD2 4.33Å; Y256-F454 HydrophobicContact CE2-CB 3.58Å; Y256-F454 HydrophobicContact CE2-CD2 4.26Å; Y256-F454 HydrophobicContact CE2-CG 4.42Å; K450-F454 PolarHBondContact O-N 3.17Å; L451-F454 WeakPolarHBondContact O-CB 3.4Å; L451-F454 PolarHBondContact O-N 3.39Å; F452-F454 VanDerWaalsContact C-N 3.29Å; F452-F454 PolarHBondContact O-N 3.44Å; F454-T456 PolarHBondContact O-N 2.81Å; F454-A457 PolarHBondContact O-N 3.3Å; F454-F458 HydrophobicContact CE1-CB 4.48Å; F454-F458 WeakPolarHBondContact O-CB 3.44Å; F454-F458 PolarHBondContact O-N 2.88Å
455	A	94.7	Very high	93.1	Very high	51 Å²	51	59.6 Å²	59.6	42%	0.421	29%	0.292	S	S	.	.	H	α-helix	trans	-63.1	-40.7	179.5	0	0	0	0	0	112.5	L451 F452 G459	L451-A455 WeakPolarHBondContact O-CB 3.28Å; L451-A455 PolarHBondContact O-N 2.89Å; F452-A455 PolarHBondContact O-N 2.96Å; F452-A455 VanDerWaalsContact O-N 3.1Å; A455-G459 PolarHBondContact O-N 3.09Å
456	T	94	Very high	93.3	Very high	18 Å²	18	63.3 Å²	63.3	11%	0.11	31%	0.307	C	S	.	.	H	α-helix	trans	-67.4	-43.1	175.4	-55.7	0	0	0	0	111.5	M431 V434 F452 T453 F454 G459 T460	M431-T456 HydrophobicContact CE-CG2 4.36Å; M431-T456 HydrophobicContact CG-CG2 4.35Å; V434-T456 HydrophobicContact CG1-CG2 4.09Å; F452-T456 PolarHBondContact O-N 3.44Å; F452-T456 PolarHBondContact O-OG1 3.19Å; F452-T456 VanDerWaalsContact O-OG1 3.12Å; T453-T456 PolarHBondContact O-N 3.05Å; F454-T456 PolarHBondContact O-N 2.81Å; T456-G459 PolarHBondContact O-N 3.08Å; T456-T460 WeakPolarHBondContact O-CG2 3.43Å; T456-T460 PolarHBondContact O-N 3.44Å; T456-T460 PolarHBondContact O-OG1 3.3Å
457	A	94.8	Very high	93.7	Very high	2 Å²	2	57.2 Å²	57.2	2%	0.017	28%	0.28	C	S	.	.	H	α-helix	trans	-64.4	-42	176.1	0	0	0	0	0	112.2	V252 M431 T453 F454 T460 F461	V252-A457 HydrophobicContact CG1-CB 3.96Å; V252-A457 WeakPolarHBondContact CG1-O 3.13Å; M431-A457 HydrophobicContact CE-CB 3.96Å; M431-A457 HydrophobicContact SD-CB 4.11Å; T453-A457 VanDerWaalsContact O-CB 3.26Å; T453-A457 WeakPolarHBondContact O-CB 3.23Å; T453-A457 PolarHBondContact O-N 2.89Å; F454-A457 PolarHBondContact O-N 3.3Å; A457-T460 WeakPolarHBondContact CA-OG1 3.25Å; A457-T460 PolarHBondContact O-OG1 3.25Å; A457-F461 WeakPolarHBondContact O-CB 3.22Å; A457-F461 PolarHBondContact O-N 3.14Å
458	F	94.8	Very high	94	Very high	95 Å²	95	47.5 Å²	47.5	42%	0.417	24%	0.244	S	C	.	.	H	α-helix	trans	-70.2	-38.4	175.9	-173.8	-106.5	0	0	0	112.3	F454 F461 L462	F454-F458 HydrophobicContact CE1-CB 4.48Å; F454-F458 WeakPolarHBondContact O-CB 3.44Å; F454-F458 PolarHBondContact O-N 2.88Å; F458-F461 HydrophobicContact CD2-CD1 4.24Å; F458-F461 HydrophobicContact CE2-CD1 4.17Å; F458-F461 WeakPolarHBondContact O-CB 3.5Å; F458-F461 PolarHBondContact O-N 2.97Å; F458-L462 HydrophobicContact CD1-CD1 4.06Å; F458-L462 HydrophobicContact CD1-CG 4.34Å; F458-L462 HydrophobicContact CE1-CD1 3.64Å; F458-L462 HydrophobicContact CE1-CD2 4.26Å; F458-L462 HydrophobicContact CE1-CG 4Å; F458-L462 HydrophobicContact CZ-CD1 4.23Å; F458-L462 HydrophobicContact CZ-CD2 4Å; F458-L462 HydrophobicContact CZ-CG 4.19Å; F458-L462 WeakPolarHBondContact O-CG 3.41Å; F458-L462 PolarHBondContact O-N 2.88Å
459	G	94.9	Very high	94.2	Very high	29 Å²	29	44.6 Å²	44.6	30%	0.299	23%	0.229	S	C	.	.	H	α-helix	trans	-63.9	-43.2	175.3	0	0	0	0	0	112.5	A455 T456 F461 L462 V463	A455-G459 PolarHBondContact O-N 3.09Å; T456-G459 PolarHBondContact O-N 3.08Å; G459-F461 VanDerWaalsContact C-N 3.35Å; G459-L462 PolarHBondContact O-N 2.9Å; G459-V463 PolarHBondContact O-N 3.14Å
460	T	94	Very high	94.3	Very high	4 Å²	4	43.5 Å²	43.5	3%	0.025	23%	0.226	C	C	.	.	H	α-helix	trans	-64.5	-38.7	173.8	48.1	0	0	0	0	111.9	L154 F158 M431 T456 A457 V463 A464	L154-T460 HydrophobicContact CD1-CG2 3.64Å; F158-T460 HydrophobicContact CD1-CG2 4.01Å; F158-T460 HydrophobicContact CE1-CG2 3.92Å; M431-T460 HydrophobicContact CE-CG2 4.27Å; M431-T460 WeakPolarHBondContact CE-OG1 3.07Å; T456-T460 WeakPolarHBondContact O-CG2 3.43Å; T456-T460 PolarHBondContact O-N 3.44Å; T456-T460 PolarHBondContact O-OG1 3.3Å; A457-T460 WeakPolarHBondContact CA-OG1 3.25Å; A457-T460 PolarHBondContact O-OG1 3.25Å; T460-V463 PolarHBondContact O-N 2.92Å; T460-A464 WeakPolarHBondContact O-CB 3.43Å; T460-A464 PolarHBondContact O-N 3.36Å
461	F	95.2	Very high	94.2	Very high	27 Å²	27	37.6 Å²	37.6	12%	0.118	20%	0.2	C	C	.	.	H	α-helix	trans	-56	-50.6	171.4	170	-103.6	0	0	0	112.5	T245 L248 V249 V252 A457 F458 G459 V463 A464 L465	T245-F461 HydrophobicContact CG2-CE2 4.47Å; T245-F461 HydrophobicContact CG2-CZ 4.27Å; L248-F461 HydrophobicContact CB-CE2 4.45Å; L248-F461 HydrophobicContact CD2-CD2 3.72Å; L248-F461 HydrophobicContact CD2-CE2 3.92Å; L248-F461 HydrophobicContact CG-CD2 3.84Å; L248-F461 HydrophobicContact CG-CE2 4.14Å; V249-F461 HydrophobicContact CG2-CD2 4.42Å; V249-F461 HydrophobicContact CG2-CE2 3.51Å; V249-F461 HydrophobicContact CG2-CZ 3.7Å; V252-F461 HydrophobicContact CG1-CB 4.3Å; V252-F461 HydrophobicContact CG2-CB 4Å; V252-F461 HydrophobicContact CG2-CD2 4.24Å; A457-F461 WeakPolarHBondContact O-CB 3.22Å; A457-F461 PolarHBondContact O-N 3.14Å; F458-F461 HydrophobicContact CD2-CD1 4.24Å; F458-F461 HydrophobicContact CE2-CD1 4.17Å; F458-F461 WeakPolarHBondContact O-CB 3.5Å; F458-F461 PolarHBondContact O-N 2.97Å; G459-F461 VanDerWaalsContact C-N 3.35Å; F461-V463 VanDerWaalsContact C-N 3.31Å; F461-V463 PolarHBondContact O-N 2.93Å; F461-A464 PolarHBondContact O-N 2.93Å; F461-L465 HydrophobicContact CE1-CD1 4.24Å; F461-L465 HydrophobicContact CE1-CD2 4.38Å; F461-L465 HydrophobicContact CE1-CG 4.46Å; F461-L465 HydrophobicContact CE2-CD2 3.97Å; F461-L465 HydrophobicContact CZ-CD1 4.43Å; F461-L465 HydrophobicContact CZ-CD2 3.81Å; F461-L465 HydrophobicContact CZ-CG 4.37Å; F461-L465 WeakPolarHBondContact O-CG 3.38Å; F461-L465 PolarHBondContact O-N 3.3Å; F461-L465 VanDerWaalsContact O-N 3.1Å
462	L	95.5	Very high	94.2	Very high	81 Å²	81	32.2 Å²	32.2	42%	0.424	17%	0.172	S	C	.	.	H	α-helix	trans	-60.1	-39.6	-177.6	-71	178.9	0	0	0	112.8	F458 G459 L465	F458-L462 HydrophobicContact CD1-CD1 4.06Å; F458-L462 HydrophobicContact CD1-CG 4.34Å; F458-L462 HydrophobicContact CE1-CD1 3.64Å; F458-L462 HydrophobicContact CE1-CD2 4.26Å; F458-L462 HydrophobicContact CE1-CG 4Å; F458-L462 HydrophobicContact CZ-CD1 4.23Å; F458-L462 HydrophobicContact CZ-CD2 4Å; F458-L462 HydrophobicContact CZ-CG 4.19Å; F458-L462 WeakPolarHBondContact O-CG 3.41Å; F458-L462 PolarHBondContact O-N 2.88Å; G459-L462 PolarHBondContact O-N 2.9Å; L462-L465 HydrophobicContact CD2-CD1 4.39Å; L462-L465 WeakPolarHBondContact O-CB 3.28Å
463	V	94.5	Very high	94.1	Very high	51 Å²	51	31.1 Å²	31.1	31%	0.309	17%	0.167	S	C	.	.	H	α-helix	trans	-76.7	-36.5	178.2	-176.8	0	0	0	0	111.3	F158 G459 T460 F461 L465 F466	F158-V463 HydrophobicContact CB-CB 4.5Å; F158-V463 HydrophobicContact CB-CG1 4.02Å; F158-V463 HydrophobicContact CD1-CB 3.74Å; F158-V463 HydrophobicContact CD1-CG1 3.95Å; F158-V463 HydrophobicContact CD1-CG2 4.32Å; F158-V463 HydrophobicContact CD2-CB 4.24Å; F158-V463 HydrophobicContact CD2-CG1 3.55Å; F158-V463 HydrophobicContact CE1-CB 3.89Å; F158-V463 HydrophobicContact CE1-CG1 4.25Å; F158-V463 HydrophobicContact CE1-CG2 3.95Å; F158-V463 HydrophobicContact CE2-CB 4.36Å; F158-V463 HydrophobicContact CE2-CG1 3.87Å; F158-V463 HydrophobicContact CE2-CG2 4.39Å; F158-V463 HydrophobicContact CG-CB 3.93Å; F158-V463 HydrophobicContact CG-CG1 3.59Å; F158-V463 HydrophobicContact CZ-CB 4.2Å; F158-V463 HydrophobicContact CZ-CG1 4.21Å; F158-V463 HydrophobicContact CZ-CG2 3.98Å; G459-V463 PolarHBondContact O-N 3.14Å; T460-V463 PolarHBondContact O-N 2.92Å; F461-V463 VanDerWaalsContact C-N 3.31Å; F461-V463 PolarHBondContact O-N 2.93Å; V463-L465 PolarHBondContact O-N 2.9Å; V463-F466 WeakPolarHBondContact O-CD2 3.46Å; V463-F466 PolarHBondContact O-N 2.92Å; V463-F466 VanDerWaalsContact O-N 3.14Å
464	A	95	Very high	94	Very high	0 Å²	0	32 Å²	32	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-61.5	-22.7	174.9	0	0	0	0	0	112.9	F158 V162 L248 T460 F461 F466 C467 I468	F158-A464 WeakPolarHBondContact O-CA 3.48Å; F158-A464 VanDerWaalsContact O-CB 3.22Å; F158-A464 WeakPolarHBondContact O-CB 3.39Å; V162-A464 HydrophobicContact CG2-CB 4.07Å; L248-A464 HydrophobicContact CD1-CB 4.28Å; L248-A464 HydrophobicContact CD2-CB 3.73Å; T460-A464 WeakPolarHBondContact O-CB 3.43Å; T460-A464 PolarHBondContact O-N 3.36Å; F461-A464 PolarHBondContact O-N 2.93Å; A464-F466 PolarHBondContact O-N 3.28Å; A464-C467 WeakPolarHBondContact O-CB 3.21Å; A464-C467 PolarHBondContact O-N 3.44Å; A464-I468 PolarHBondContact O-N 3Å
465	L	94.8	Very high	94	Very high	40 Å²	40	28.2 Å²	28.2	21%	0.209	16%	0.156	C	C	.	.	H	α-helix	trans	-55.4	-35	172.9	-68.2	-179.8	0	0	0	112.9	T245 L248 F461 L462 V463 C467 I468	T245-L465 HydrophobicContact CG2-CD2 3.9Å; L248-L465 HydrophobicContact CD2-CD2 4.39Å; F461-L465 HydrophobicContact CE1-CD1 4.24Å; F461-L465 HydrophobicContact CE1-CD2 4.38Å; F461-L465 HydrophobicContact CE1-CG 4.46Å; F461-L465 HydrophobicContact CE2-CD2 3.97Å; F461-L465 HydrophobicContact CZ-CD1 4.43Å; F461-L465 HydrophobicContact CZ-CD2 3.81Å; F461-L465 HydrophobicContact CZ-CG 4.37Å; F461-L465 WeakPolarHBondContact O-CG 3.38Å; F461-L465 PolarHBondContact O-N 3.3Å; F461-L465 VanDerWaalsContact O-N 3.1Å; L462-L465 HydrophobicContact CD2-CD1 4.39Å; L462-L465 WeakPolarHBondContact O-CB 3.28Å; V463-L465 PolarHBondContact O-N 2.9Å; L465-C467 PolarHBondContact O-N 2.79Å; L465-I468 HydrophobicContact CD2-CD1 3.69Å; L465-I468 HydrophobicContact CD2-CG1 4.39Å; L465-I468 WeakPolarHBondContact O-CG1 3.3Å; L465-I468 PolarHBondContact O-N 3.34Å
466	F	93.6	Very high	93.9	Very high	121 Å²	121	26.4 Å²	26.4	53%	0.531	14%	0.139	S	C	.	.	H	α-helix	trans	-65.7	-30	177.5	-67.3	-73	0	0	0	112.5	V463 A464 T469	V463-F466 WeakPolarHBondContact O-CD2 3.46Å; V463-F466 PolarHBondContact O-N 2.92Å; V463-F466 VanDerWaalsContact O-N 3.14Å; A464-F466 PolarHBondContact O-N 3.28Å; F466-T469 PolarHBondContact O-OG1 2.81Å
467	C	94.1	Very high	93.8	Very high	2 Å²	2	26.6 Å²	26.6	1%	0.014	14%	0.14	C	C	.	.	H	α-helix	trans	-84.3	-9.2	-179.2	-65.7	0	0	0	0	113.7	V162 A464 L465 G472	V162-C467 HydrophobicContact CB-CB 4.5Å; V162-C467 HydrophobicContact CG1-CB 4.49Å; V162-C467 HydrophobicContact CG2-CB 3.65Å; A464-C467 WeakPolarHBondContact O-CB 3.21Å; A464-C467 PolarHBondContact O-N 3.44Å; L465-C467 PolarHBondContact O-N 2.79Å; C467-G472 CarbonylContact O-C 3.24Å; C467-G472 WeakPolarHBondContact O-CA 3.16Å
468	I	94.4	Very high	93.7	Very high	2 Å²	2	26.8 Å²	26.8	1%	0.01	14%	0.141	C	C	.	.	T	Hydrogen-bonded Turn	trans	-108.2	13.9	175.3	60.6	167	0	0	0	113.2	V162 P240 R241 L244 T245 L248 A464 L465	V162-I468 HydrophobicContact CB-CG2 4.34Å; V162-I468 HydrophobicContact CG1-CG2 3.59Å; V162-I468 HydrophobicContact CG2-CG2 4.02Å; P240-I468 HydrophobicContact CB-CG1 4.45Å; R241-I468 PolarHBondContact N-O 2.95Å; L244-I468 HydrophobicContact CB-CB 4.19Å; L244-I468 HydrophobicContact CB-CG2 4.29Å; T245-I468 HydrophobicContact CG2-CD1 4.43Å; T245-I468 WeakPolarHBondContact OG1-CD1 3.38Å; L248-I468 HydrophobicContact CD2-CD1 4.06Å; A464-I468 PolarHBondContact O-N 3Å; L465-I468 HydrophobicContact CD2-CD1 3.69Å; L465-I468 HydrophobicContact CD2-CG1 4.39Å; L465-I468 WeakPolarHBondContact O-CG1 3.3Å; L465-I468 PolarHBondContact O-N 3.34Å
469	T	94.7	Very high	93.6	Very high	9 Å²	9	23.2 Å²	23.2	6%	0.055	13%	0.126	C	C	.	.	B	Isolated β-bridge	trans	-72.9	167.9	168.4	60.5	0	0	0	0	110.7	L237 L239 P240 F466 G471 G472	L237-T469 WeakPolarHBondContact O-CB 3.45Å; L237-T469 PolarHBondContact O-OG1 3.48Å; L239-T469 WeakPolarHBondContact O-CA 3.37Å; P240-T469 HydrophobicContact CG-CG2 4.04Å; F466-T469 PolarHBondContact O-OG1 2.81Å; T469-G471 PolarHBondContact O-N 3.42Å; T469-G472 WeakPolarHBondContact O-CA 3.41Å; T469-G472 PolarHBondContact O-N 3.47Å; T469-G472 WeakPolarHBondContact OG1-CA 3.14Å; T469-G472 PolarHBondContact OG1-N 3.39Å
470	N	92.4	Very high	93.2	Very high	15 Å²	15	25.1 Å²	25.1	8%	0.08	13%	0.129	C	C	.	.	T	Hydrogen-bonded Turn	trans	-53.9	-39.4	176.5	-66	-9.7	0	0	0	112.5	E230 L237 L239 R241	E230-N470 PolarHBondContact OE2-ND2 2.92Å; L237-N470 PolarHBondContact O-N 3.34Å; L237-N470 VanDerWaalsContact O-N 3.09Å; L239-N470 PolarHBondContact O-N 2.76Å; R241-N470 WeakPolarHBondContact CD-OD1 3.27Å
471	G	91.4	Very high	92.9	Very high	0 Å²	0	31.2 Å²	31.2	0%	0	16%	0.156	C	C	.	.	T	Hydrogen-bonded Turn	trans	-92	11.3	173.8	0	0	0	0	0	114.4	S231 L237 T469 I473 Y474	S231-G471 WeakPolarHBondContact OG-CA 3.41Å; L237-G471 PolarHBondContact O-N 3.4Å; T469-G471 PolarHBondContact O-N 3.42Å; G471-I473 VanDerWaalsContact C-N 3.26Å; G471-I473 PolarHBondContact O-N 3.39Å; G471-Y474 WeakPolarHBondContact O-CB 3.16Å; G471-Y474 WeakPolarHBondContact O-CD2 3.45Å; G471-Y474 PolarHBondContact O-N 3.23Å; G471-Y474 VanDerWaalsContact O-N 3.09Å
472	G	92.9	Very high	92.6	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-63.5	-27.3	-170.2	0	0	0	0	0	114.4	C467 T469 Y474 V475 L476	C467-G472 CarbonylContact O-C 3.24Å; C467-G472 WeakPolarHBondContact O-CA 3.16Å; T469-G472 WeakPolarHBondContact O-CA 3.41Å; T469-G472 PolarHBondContact O-N 3.47Å; T469-G472 WeakPolarHBondContact OG1-CA 3.14Å; T469-G472 PolarHBondContact OG1-N 3.39Å; G472-Y474 PolarHBondContact O-N 3Å; G472-V475 WeakPolarHBondContact O-CB 3.46Å; G472-V475 PolarHBondContact O-N 3.43Å; G472-V475 VanDerWaalsContact O-N 3.12Å; G472-L476 PolarHBondContact O-N 3.39Å
473	I	91.3	Very high	92.2	Very high	4 Å²	4	27 Å²	27	2%	0.021	13%	0.133	C	C	.	.	H	α-helix	trans	-60.5	-32.4	174.8	-169.4	63.3	0	0	0	112.5	W166 L226 L228 G471 L476 T477 Y552	W166-I473 HydrophobicContact CH2-CD1 3.6Å; W166-I473 HydrophobicContact CZ2-CD1 4.45Å; W166-I473 HydrophobicContact CZ3-CD1 4.33Å; L226-I473 HydrophobicContact CD1-CB 4.33Å; L226-I473 HydrophobicContact CD1-CG1 4.5Å; L228-I473 HydrophobicContact CD1-CG2 3.47Å; L228-I473 VanDerWaalsContact CD1-CG2 3.47Å; L228-I473 HydrophobicContact CD2-CG2 4.1Å; L228-I473 HydrophobicContact CG-CG2 4.38Å; G471-I473 VanDerWaalsContact C-N 3.26Å; G471-I473 PolarHBondContact O-N 3.39Å; I473-L476 HydrophobicContact CD1-CD2 4.3Å; I473-L476 PolarHBondContact O-N 3.13Å; I473-T477 WeakPolarHBondContact O-CB 3.35Å; I473-T477 PolarHBondContact O-N 3.27Å; I473-T477 PolarHBondContact O-OG1 2.65Å; I473-Y552 HydrophobicContact CD1-CE2 4.2Å; I473-Y552 HydrophobicContact CG1-CD2 4.45Å; I473-Y552 HydrophobicContact CG1-CE1 4.19Å; I473-Y552 HydrophobicContact CG1-CE2 3.65Å; I473-Y552 WeakPolarHBondContact CG1-OH 3.4Å; I473-Y552 HydrophobicContact CG2-CE1 4.39Å
474	Y	92.6	Very high	91.7	Very high	19 Å²	19	24.5 Å²	24.5	8%	0.075	12%	0.118	C	C	.	.	H	α-helix	trans	-69.2	-39.2	176.4	-61.5	-60.6	0	0	0	111.3	L228 G233 G471 G472 L478 Y552 Y555 F557	L228-Y474 HydrophobicContact CD1-CD2 4.37Å; L228-Y474 HydrophobicContact CD1-CE2 3.62Å; G233-Y474 VanDerWaalsContact CA-CE2 3.49Å; G471-Y474 WeakPolarHBondContact O-CB 3.16Å; G471-Y474 WeakPolarHBondContact O-CD2 3.45Å; G471-Y474 PolarHBondContact O-N 3.23Å; G471-Y474 VanDerWaalsContact O-N 3.09Å; G472-Y474 PolarHBondContact O-N 3Å; Y474-L478 WeakPolarHBondContact O-CB 3.4Å; Y474-L478 PolarHBondContact O-N 3.16Å; Y474-Y552 HydrophobicContact CD1-CD1 4.33Å; Y474-Y552 HydrophobicContact CD1-CG 4.49Å; Y474-Y552 AromaticContact CE1-CD1 3.9Å; Y474-Y552 HydrophobicContact CE1-CD1 3.9Å; Y474-Y552 HydrophobicContact CE1-CG 4.43Å; Y474-Y555 AromaticContact CD1-CD1 3.71Å; Y474-Y555 HydrophobicContact CD1-CD1 3.71Å; Y474-Y555 AromaticContact CD1-CE1 3.96Å; Y474-Y555 HydrophobicContact CD1-CE1 3.96Å; Y474-Y555 HydrophobicContact CD1-CG 4.39Å; Y474-Y555 AromaticContact CE1-CD1 3.46Å; Y474-Y555 HydrophobicContact CE1-CD1 3.46Å; Y474-Y555 VanDerWaalsContact CE1-CD1 3.46Å; Y474-Y555 HydrophobicContact CE1-CD2 4.43Å; Y474-Y555 HydrophobicContact CE1-CE1 4.04Å; Y474-Y555 AromaticContact CE1-CG 3.68Å; Y474-Y555 HydrophobicContact CE1-CG 3.68Å; Y474-F557 HydrophobicContact CD1-CE2 4.38Å; Y474-F557 AromaticContact CD1-CZ 3.92Å; Y474-F557 HydrophobicContact CD1-CZ 3.92Å; Y474-F557 HydrophobicContact CG-CZ 4.43Å; Y474-F557 WeakPolarHBondContact O-CE1 3.45Å; Y474-F557 WeakPolarHBondContact O-CZ 3.35Å
475	V	94.3	Very high	91.1	Very high	22 Å²	22	25.1 Å²	25.1	13%	0.133	12%	0.124	C	C	.	.	H	α-helix	trans	-67.2	-44.6	175.3	-175.5	0	0	0	0	110.4	I234 L237 G472 T477 L478 L479	I234-V475 HydrophobicContact CG1-CG2 4.38Å; L237-V475 HydrophobicContact CD1-CG2 4.14Å; L237-V475 HydrophobicContact CD2-CG2 3.48Å; L237-V475 VanDerWaalsContact CD2-CG2 3.48Å; L237-V475 HydrophobicContact CG-CG2 4.49Å; G472-V475 WeakPolarHBondContact O-CB 3.46Å; G472-V475 PolarHBondContact O-N 3.43Å; G472-V475 VanDerWaalsContact O-N 3.12Å; V475-T477 VanDerWaalsContact C-N 3.34Å; V475-T477 PolarHBondContact O-N 2.92Å; V475-L478 WeakPolarHBondContact O-CB 3.16Å; V475-L478 PolarHBondContact O-N 2.87Å; V475-L479 HydrophobicContact CG1-CD1 4.14Å; V475-L479 HydrophobicContact CG1-CG 4.45Å; V475-L479 WeakPolarHBondContact O-CG 3.45Å; V475-L479 PolarHBondContact O-N 3.01Å
476	L	93.1	Very high	90.6	Very high	13 Å²	13	23.9 Å²	23.9	7%	0.068	12%	0.119	C	C	.	.	H	α-helix	trans	-58.7	-46.3	176	-177.2	141.5	0	0	0	111.1	Y159 V162 I163 W166 G472 I473 L478 L479 D480	Y159-L476 HydrophobicContact CD2-CG 4.29Å; V162-L476 HydrophobicContact CB-CD1 4.17Å; V162-L476 HydrophobicContact CG1-CD1 4.17Å; I163-L476 HydrophobicContact CG1-CD1 4.18Å; W166-L476 HydrophobicContact CH2-CD1 3.61Å; W166-L476 HydrophobicContact CH2-CD2 4.41Å; W166-L476 HydrophobicContact CZ2-CD1 4.21Å; W166-L476 HydrophobicContact CZ3-CD1 4.13Å; G472-L476 PolarHBondContact O-N 3.39Å; I473-L476 HydrophobicContact CD1-CD2 4.3Å; I473-L476 PolarHBondContact O-N 3.13Å; L476-L478 VanDerWaalsContact C-N 3.33Å; L476-L478 PolarHBondContact O-N 3.28Å; L476-L479 PolarHBondContact O-N 2.91Å; L476-D480 VanDerWaalsContact O-CB 3.29Å; L476-D480 WeakPolarHBondContact O-CB 3.41Å; L476-D480 PolarHBondContact O-N 3.31Å
477	T	90.9	Very high	90.4	Very high	22 Å²	22	18.1 Å²	18.1	14%	0.135	9%	0.093	C	C	.	.	H	α-helix	trans	-63.1	-39.7	179	-56.9	0	0	0	0	111.9	I473 V475 K481 L550 Y552 F557	I473-T477 WeakPolarHBondContact O-CB 3.35Å; I473-T477 PolarHBondContact O-N 3.27Å; I473-T477 PolarHBondContact O-OG1 2.65Å; V475-T477 VanDerWaalsContact C-N 3.34Å; V475-T477 PolarHBondContact O-N 2.92Å; T477-K481 WeakPolarHBondContact O-CB 3.48Å; T477-K481 PolarHBondContact O-N 3.11Å; T477-K481 VanDerWaalsContact O-N 3.15Å; T477-L550 HydrophobicContact CG2-CD1 4.22Å; T477-Y552 HydrophobicContact CG2-CD2 4.12Å; T477-Y552 WeakPolarHBondContact OG1-CD2 3.49Å; T477-F557 HydrophobicContact CG2-CE2 4.5Å; T477-F557 HydrophobicContact CG2-CZ 4.41Å
478	L	92.5	Very high	90.2	Very high	7 Å²	7	18.2 Å²	18.2	4%	0.037	9%	0.093	C	C	.	.	H	α-helix	trans	-62.2	-48.3	174.9	-175.1	105.3	0	0	0	111.4	I234 Y474 V475 L476 Y482 L550 F557 A561 L564	I234-L478 HydrophobicContact CD1-CD1 4.41Å; Y474-L478 WeakPolarHBondContact O-CB 3.4Å; Y474-L478 PolarHBondContact O-N 3.16Å; V475-L478 WeakPolarHBondContact O-CB 3.16Å; V475-L478 PolarHBondContact O-N 2.87Å; L476-L478 VanDerWaalsContact C-N 3.33Å; L476-L478 PolarHBondContact O-N 3.28Å; L478-Y482 HydrophobicContact CD1-CD2 4.5Å; L478-Y482 HydrophobicContact CG-CD2 4.43Å; L478-Y482 WeakPolarHBondContact O-CB 3.35Å; L478-Y482 WeakPolarHBondContact O-CD2 2.99Å; L478-Y482 PolarHBondContact O-N 2.66Å; L478-L550 HydrophobicContact CB-CD2 4.15Å; L478-L550 HydrophobicContact CD1-CD2 3.98Å; L478-F557 HydrophobicContact CD1-CD1 4.45Å; L478-A561 HydrophobicContact CD1-CB 4.17Å; L478-A561 WeakPolarHBondContact CD1-O 3.14Å; L478-L564 HydrophobicContact CD2-CD2 4.29Å
479	L	92.6	Very high	90	Very high	20 Å²	20	18.2 Å²	18.2	11%	0.105	9%	0.094	C	C	.	.	H	α-helix	trans	-67.4	-44.7	-179.7	-69	176.6	0	0	0	111.8	F158 Y159 V475 L476 K481 Y482 A483 V568	F158-L479 HydrophobicContact CB-CD1 4.46Å; Y159-L479 HydrophobicContact CD1-CB 3.62Å; Y159-L479 HydrophobicContact CD1-CD1 4.49Å; Y159-L479 HydrophobicContact CE1-CB 4.25Å; Y159-L479 HydrophobicContact CG-CB 4.19Å; V475-L479 HydrophobicContact CG1-CD1 4.14Å; V475-L479 HydrophobicContact CG1-CG 4.45Å; V475-L479 WeakPolarHBondContact O-CG 3.45Å; V475-L479 PolarHBondContact O-N 3.01Å; L476-L479 PolarHBondContact O-N 2.91Å; L479-K481 VanDerWaalsContact C-N 3.29Å; L479-K481 PolarHBondContact O-N 2.77Å; L479-Y482 PolarHBondContact O-N 3.17Å; L479-A483 WeakPolarHBondContact O-CA 3.5Å; L479-A483 WeakPolarHBondContact O-CB 3.29Å; L479-A483 PolarHBondContact O-N 2.98Å; L479-V568 HydrophobicContact CD2-CG1 4.35Å
480	D	87.9	Confident	89.8	Confident	69 Å²	69	19.7 Å²	19.7	37%	0.369	10%	0.099	S	C	.	.	H	α-helix	trans	-56.5	-44.4	177.8	-177.6	53.9	0	0	0	111.4	Y159 L476	Y159-D480 HydrophobicContact CD2-CB 4.35Å; Y159-D480 HydrophobicContact CE2-CB 3.97Å; Y159-D480 PolarHBondContact OH-OD1 3.48Å; L476-D480 VanDerWaalsContact O-CB 3.29Å; L476-D480 WeakPolarHBondContact O-CB 3.41Å; L476-D480 PolarHBondContact O-N 3.31Å
481	K	86.5	Confident	89.8	Confident	132 Å²	132	19 Å²	19	57%	0.574	10%	0.095	S	C	*	.	H	α-helix	trans	-69.8	-47.9	178.9	-173.4	64.8	173.7	-176.3	0	113.4	T477 L479 L550	T477-K481 WeakPolarHBondContact O-CB 3.48Å; T477-K481 PolarHBondContact O-N 3.11Å; T477-K481 VanDerWaalsContact O-N 3.15Å; L479-K481 VanDerWaalsContact C-N 3.29Å; L479-K481 PolarHBondContact O-N 2.77Å; K481-L550 HydrophobicContact CB-CD1 3.95Å; K481-L550 HydrophobicContact CG-CD1 3.96Å
482	Y	88.6	Confident	89.9	Confident	18 Å²	18	19 Å²	19	7%	0.071	10%	0.095	C	C	.	.	H	α-helix	trans	-101.8	-28	-166.2	-74.1	-75.4	0	0	0	115.2	L478 L479 A484 L550 N562 G565 W566 A569	L478-Y482 HydrophobicContact CD1-CD2 4.5Å; L478-Y482 HydrophobicContact CG-CD2 4.43Å; L478-Y482 WeakPolarHBondContact O-CB 3.35Å; L478-Y482 WeakPolarHBondContact O-CD2 2.99Å; L478-Y482 PolarHBondContact O-N 2.66Å; L479-Y482 PolarHBondContact O-N 3.17Å; Y482-A484 PolarHBondContact O-N 3.19Å; Y482-L550 HydrophobicContact CE2-CB 4.41Å; Y482-L550 HydrophobicContact CE2-CD2 4.26Å; Y482-N562 PolarHBondContact OH-OD1 3.4Å; Y482-G565 WeakPolarHBondContact CB-O 3.23Å; Y482-W566 AromaticContact CE1-CD1 3.91Å; Y482-W566 HydrophobicContact CE1-CD2 4.17Å; Y482-W566 AromaticContact CE1-CE2 3.92Å; Y482-W566 HydrophobicContact CE1-CG 4.18Å; Y482-W566 AromaticContact CE1-NE1 3.76Å; Y482-A569 WeakPolarHBondContact O-CB 3.3Å
483	A	88.4	Confident	90	Very high	0 Å²	0	19.5 Å²	19.5	0%	0	10%	0.098	C	C	.	.	T	Hydrogen-bonded Turn	trans	-69.6	-36.4	-172.9	0	0	0	0	0	113.2	Y155 L479 V568	Y155-A483 HydrophobicContact CD2-CB 4.23Å; Y155-A483 HydrophobicContact CG-CB 4.39Å; L479-A483 WeakPolarHBondContact O-CA 3.5Å; L479-A483 WeakPolarHBondContact O-CB 3.29Å; L479-A483 PolarHBondContact O-N 2.98Å; A483-V568 HydrophobicContact CB-CG1 4.11Å
484	A	82.9	Confident	90.2	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	10%	0.104	C	C	.	.	S	Bend	trans	-113.8	-34.1	-173.7	0	0	0	0	0	112.9	I152 V156 Y324 Y482 I488	I152-A484 HydrophobicContact CG2-CB 4.4Å; V156-A484 HydrophobicContact CG2-CB 3.72Å; Y324-A484 HydrophobicContact CE1-CB 3.78Å; Y324-A484 VanDerWaalsContact OH-C 3.24Å; Y324-A484 VanDerWaalsContact OH-CB 3.25Å; Y324-A484 WeakPolarHBondContact OH-CB 3.49Å; Y482-A484 PolarHBondContact O-N 3.19Å; A484-I488 HydrophobicContact CB-CD1 3.49Å; A484-I488 VanDerWaalsContact CB-CD1 3.49Å; A484-I488 HydrophobicContact CB-CG1 4.29Å; A484-I488 VanDerWaalsContact O-CB 3.22Å; A484-I488 WeakPolarHBondContact O-CB 3.15Å; A484-I488 VanDerWaalsContact O-CD1 3.27Å; A484-I488 WeakPolarHBondContact O-CD1 3.36Å; A484-I488 WeakPolarHBondContact O-CG1 3.29Å; A484-I488 PolarHBondContact O-N 3.03Å
485	G	82.2	Confident	90.3	Very high	12 Å²	12	19.8 Å²	19.8	12%	0.124	10%	0.101	C	C	.	.	H	α-helix	trans	-52.9	-82.3	-163.9	0	0	0	0	0	114.8	Y324 A487	Y324-G485 WeakPolarHBondContact OH-CA 3.37Å; Y324-G485 PolarHBondContact OH-N 3.18Å; G485-A487 VanDerWaalsContact C-N 3.28Å; G485-A487 PolarHBondContact O-N 3.46Å
486	T	85.1	Confident	90.3	Very high	15 Å²	15	18.7 Å²	18.7	9%	0.092	9%	0.094	C	C	.	.	H	α-helix	trans	-70.3	-28.7	179.7	-54	0	0	0	0	111.9	L489 F490 V540 S543 T544	T486-L489 PolarHBondContact O-N 3.4Å; T486-F490 WeakPolarHBondContact O-CB 3.22Å; T486-F490 PolarHBondContact O-N 3.21Å; T486-V540 HydrophobicContact CG2-CG1 4.48Å; T486-S543 PolarHBondContact OG1-OG 3.3Å; T486-T544 HydrophobicContact CG2-CG2 3.82Å
487	A	89.3	Confident	90.4	Very high	0 Å²	0	20.3 Å²	20.3	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-65	-42.3	-177.6	0	0	0	0	0	113.2	I152 G485 F490 G491 S572 M573	I152-A487 HydrophobicContact CD1-CB 3.91Å; I152-A487 HydrophobicContact CG1-CB 4.18Å; G485-A487 VanDerWaalsContact C-N 3.28Å; G485-A487 PolarHBondContact O-N 3.46Å; A487-F490 PolarHBondContact O-N 3.26Å; A487-G491 PolarHBondContact O-N 3.45Å; A487-S572 WeakPolarHBondContact CB-OG 3.41Å; A487-M573 HydrophobicContact CB-CG 4.24Å
488	I	89.9	Confident	90.6	Very high	3 Å²	3	19.3 Å²	19.3	2%	0.015	10%	0.096	C	C	.	.	H	α-helix	trans	-64.6	-48.8	176.1	-71.2	164.7	0	0	0	110.4	I152 Y324 F330 A484 F490 G491 V492	I152-I488 HydrophobicContact CD1-CG1 4.14Å; I152-I488 HydrophobicContact CG2-CD1 3.95Å; I152-I488 HydrophobicContact CG2-CG1 3.53Å; Y324-I488 HydrophobicContact CE1-CD1 4.21Å; F330-I488 HydrophobicContact CD1-CD1 4.35Å; F330-I488 HydrophobicContact CD2-CD1 4.28Å; F330-I488 HydrophobicContact CE1-CD1 3.56Å; F330-I488 HydrophobicContact CE1-CG1 4.4Å; F330-I488 HydrophobicContact CE2-CD1 3.5Å; F330-I488 HydrophobicContact CZ-CD1 3.1Å; F330-I488 HydrophobicContact CZ-CG1 4.27Å; A484-I488 HydrophobicContact CB-CD1 3.49Å; A484-I488 VanDerWaalsContact CB-CD1 3.49Å; A484-I488 HydrophobicContact CB-CG1 4.29Å; A484-I488 VanDerWaalsContact O-CB 3.22Å; A484-I488 WeakPolarHBondContact O-CB 3.15Å; A484-I488 VanDerWaalsContact O-CD1 3.27Å; A484-I488 WeakPolarHBondContact O-CD1 3.36Å; A484-I488 WeakPolarHBondContact O-CG1 3.29Å; A484-I488 PolarHBondContact O-N 3.03Å; I488-F490 PolarHBondContact O-N 3.36Å; I488-G491 WeakPolarHBondContact O-CA 3.46Å; I488-G491 PolarHBondContact O-N 3.42Å; I488-V492 HydrophobicContact CG2-CG2 4.06Å; I488-V492 WeakPolarHBondContact O-CG2 3.38Å; I488-V492 PolarHBondContact O-N 3.04Å
489	L	89.4	Confident	90.7	Very high	3 Å²	3	19 Å²	19	2%	0.016	10%	0.095	C	C	.	.	H	α-helix	trans	-59	-39.2	-179.2	-62.5	176.6	0	0	0	111.3	F323 T486 L493 L536 V539 V540	F323-L489 HydrophobicContact CB-CD2 4.07Å; F323-L489 HydrophobicContact CD2-CD2 3.44Å; F323-L489 VanDerWaalsContact CD2-CD2 3.44Å; F323-L489 HydrophobicContact CE2-CD2 4.09Å; F323-L489 HydrophobicContact CG-CD2 3.81Å; T486-L489 PolarHBondContact O-N 3.4Å; L489-L493 VanDerWaalsContact O-CB 3.28Å; L489-L493 WeakPolarHBondContact O-CB 3.3Å; L489-L493 PolarHBondContact O-N 3.15Å; L489-L536 HydrophobicContact CD2-CD2 3.98Å; L489-V539 HydrophobicContact CD1-CG1 3.78Å; L489-V540 HydrophobicContact CB-CG2 3.59Å
490	F	91.9	Very high	90.7	Very high	39 Å²	39	18.2 Å²	18.2	17%	0.171	9%	0.091	C	C	.	.	H	α-helix	trans	-64.2	-47.7	171.5	174.2	-97.2	0	0	0	112.3	T486 A487 I488 V492 L493 I494 M573 V576	T486-F490 WeakPolarHBondContact O-CB 3.22Å; T486-F490 PolarHBondContact O-N 3.21Å; A487-F490 PolarHBondContact O-N 3.26Å; I488-F490 PolarHBondContact O-N 3.36Å; F490-V492 PolarHBondContact O-N 3.31Å; F490-L493 WeakPolarHBondContact O-CB 3.49Å; F490-L493 PolarHBondContact O-N 3.34Å; F490-I494 HydrophobicContact CD2-CG1 4.37Å; F490-I494 HydrophobicContact CE1-CG1 4.09Å; F490-I494 HydrophobicContact CE2-CD1 4.07Å; F490-I494 HydrophobicContact CE2-CG1 3.94Å; F490-I494 HydrophobicContact CZ-CD1 4.25Å; F490-I494 HydrophobicContact CZ-CG1 3.79Å; F490-I494 WeakPolarHBondContact O-CG1 3Å; F490-I494 PolarHBondContact O-N 3.33Å; F490-M573 HydrophobicContact CB-CE 3.95Å; F490-M573 HydrophobicContact CB-CG 4.31Å; F490-M573 HydrophobicContact CB-SD 4.43Å; F490-M573 HydrophobicContact CD1-CB 3.83Å; F490-M573 HydrophobicContact CD1-CE 4.03Å; F490-M573 HydrophobicContact CD1-CG 3.63Å; F490-M573 HydrophobicContact CD2-CE 3.81Å; F490-M573 HydrophobicContact CE1-CB 3.86Å; F490-M573 HydrophobicContact CE1-CE 4.49Å; F490-M573 HydrophobicContact CE1-CG 4.2Å; F490-M573 HydrophobicContact CE2-CE 4.31Å; F490-M573 HydrophobicContact CG-CE 3.65Å; F490-M573 HydrophobicContact CG-CG 4.1Å; F490-M573 HydrophobicContact CG-SD 4.48Å; F490-V576 HydrophobicContact CE1-CB 4.31Å; F490-V576 HydrophobicContact CE1-CG2 4Å
491	G	92.8	Very high	91	Very high	0 Å²	0	18.2 Å²	18.2	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-55.9	-49.2	177.9	0	0	0	0	0	112.3	A487 I488 L493 I494 E495	A487-G491 PolarHBondContact O-N 3.45Å; I488-G491 WeakPolarHBondContact O-CA 3.46Å; I488-G491 PolarHBondContact O-N 3.42Å; G491-L493 PolarHBondContact O-N 2.82Å; G491-I494 PolarHBondContact O-N 2.95Å; G491-E495 WeakPolarHBondContact O-CB 3.48Å; G491-E495 PolarHBondContact O-N 3.35Å
492	V	93	Very high	91.2	Very high	0 Å²	0	14.2 Å²	14.2	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-66.4	-35.5	178.8	-177.4	0	0	0	0	111.9	L117 F323 I488 F490 E495 A496 L536	L117-V492 HydrophobicContact CB-CG1 4.49Å; L117-V492 HydrophobicContact CD1-CG1 3.69Å; L117-V492 HydrophobicContact CD2-CG1 4.27Å; L117-V492 HydrophobicContact CG-CG1 4.37Å; F323-V492 HydrophobicContact CE1-CG1 4.24Å; I488-V492 HydrophobicContact CG2-CG2 4.06Å; I488-V492 WeakPolarHBondContact O-CG2 3.38Å; I488-V492 PolarHBondContact O-N 3.04Å; F490-V492 PolarHBondContact O-N 3.31Å; V492-E495 PolarHBondContact O-N 3.4Å; V492-A496 WeakPolarHBondContact O-CB 3.44Å; V492-A496 PolarHBondContact O-N 3.11Å; V492-L536 HydrophobicContact CB-CD1 4.19Å; V492-L536 HydrophobicContact CG1-CD1 3.68Å
493	L	94.4	Very high	91.4	Very high	11 Å²	11	13.6 Å²	13.6	6%	0.058	7%	0.066	C	C	.	.	H	α-helix	trans	-60.8	-51.4	175	172.6	62.8	0	0	0	111	L489 F490 G491 E495 A496 I497 P533 L536 L537	L489-L493 VanDerWaalsContact O-CB 3.28Å; L489-L493 WeakPolarHBondContact O-CB 3.3Å; L489-L493 PolarHBondContact O-N 3.15Å; F490-L493 WeakPolarHBondContact O-CB 3.49Å; F490-L493 PolarHBondContact O-N 3.34Å; G491-L493 PolarHBondContact O-N 2.82Å; L493-E495 VanDerWaalsContact C-N 3.27Å; L493-E495 PolarHBondContact O-N 2.85Å; L493-A496 PolarHBondContact O-N 3.37Å; L493-I497 HydrophobicContact CD1-CD1 3.85Å; L493-I497 HydrophobicContact CD1-CG1 4.41Å; L493-I497 HydrophobicContact CG-CD1 4.04Å; L493-I497 VanDerWaalsContact O-CG1 3.28Å; L493-I497 WeakPolarHBondContact O-CG1 3.45Å; L493-I497 PolarHBondContact O-N 3Å; L493-P533 HydrophobicContact CD1-CB 4.19Å; L493-P533 VanDerWaalsContact CD1-O 3.28Å; L493-P533 WeakPolarHBondContact CD1-O 3.46Å; L493-L536 HydrophobicContact CB-CB 4.14Å; L493-L536 HydrophobicContact CB-CD1 4.44Å; L493-L536 HydrophobicContact CD1-CB 3.95Å; L493-L537 HydrophobicContact CD1-CB 4.21Å; L493-L537 HydrophobicContact CD2-CB 4.23Å; L493-L537 HydrophobicContact CD2-CD1 4Å
494	I	95.3	Very high	91.6	Very high	28 Å²	28	13.8 Å²	13.8	14%	0.144	7%	0.068	C	C	.	.	H	α-helix	trans	-66.7	-34.7	178.6	-55.5	-55.6	0	0	0	110.4	F142 V145 F490 G491 I497 G498 V576	F142-I494 HydrophobicContact CD1-CG2 3.53Å; F142-I494 HydrophobicContact CE1-CG2 3.6Å; V145-I494 HydrophobicContact CG2-CB 4.05Å; V145-I494 HydrophobicContact CG2-CG2 3.48Å; V145-I494 VanDerWaalsContact CG2-CG2 3.48Å; F490-I494 HydrophobicContact CD2-CG1 4.37Å; F490-I494 HydrophobicContact CE1-CG1 4.09Å; F490-I494 HydrophobicContact CE2-CD1 4.07Å; F490-I494 HydrophobicContact CE2-CG1 3.94Å; F490-I494 HydrophobicContact CZ-CD1 4.25Å; F490-I494 HydrophobicContact CZ-CG1 3.79Å; F490-I494 WeakPolarHBondContact O-CG1 3Å; F490-I494 PolarHBondContact O-N 3.33Å; G491-I494 PolarHBondContact O-N 2.95Å; I494-I497 PolarHBondContact O-N 3.31Å; I494-G498 PolarHBondContact O-N 2.86Å; I494-V576 HydrophobicContact CG2-CG1 3.94Å
495	E	95.2	Very high	92	Very high	1 Å²	1	14 Å²	14	1%	0.005	7%	0.069	C	C	.	.	H	α-helix	trans	-60	-52.4	174.4	178.5	170	166	0	0	112	M120 E121 W136 V145 G491 V492 L493 I497 G498 V499	M120-E495 HydrophobicContact CE-CG 3.9Å; E121-E495 WeakPolarHBondContact CG-OE1 3.46Å; W136-E495 HydrophobicContact CH2-CB 4.24Å; W136-E495 HydrophobicContact CH2-CG 4.01Å; W136-E495 HydrophobicContact CZ2-CB 4.05Å; W136-E495 HydrophobicContact CZ2-CG 3.79Å; V145-E495 HydrophobicContact CG1-CB 4.04Å; G491-E495 WeakPolarHBondContact O-CB 3.48Å; G491-E495 PolarHBondContact O-N 3.35Å; V492-E495 PolarHBondContact O-N 3.4Å; L493-E495 VanDerWaalsContact C-N 3.27Å; L493-E495 PolarHBondContact O-N 2.85Å; E495-I497 VanDerWaalsContact C-N 3.29Å; E495-I497 PolarHBondContact O-N 2.89Å; E495-G498 PolarHBondContact O-N 3.5Å; E495-G498 VanDerWaalsContact O-N 3.12Å; E495-V499 HydrophobicContact CG-CG2 4.49Å; E495-V499 WeakPolarHBondContact O-CG2 3.4Å; E495-V499 PolarHBondContact O-N 3.1Å
496	A	94.9	Very high	92.4	Very high	0 Å²	0	16.1 Å²	16.1	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-60	-40.5	178.7	0	0	0	0	0	111.5	L117 M120 V492 L493 A500 P533	L117-A496 HydrophobicContact CD2-CB 3.76Å; M120-A496 HydrophobicContact CE-CB 4.35Å; V492-A496 WeakPolarHBondContact O-CB 3.44Å; V492-A496 PolarHBondContact O-N 3.11Å; L493-A496 PolarHBondContact O-N 3.37Å; A496-A500 WeakPolarHBondContact O-CB 3.47Å; A496-A500 PolarHBondContact O-N 3.45Å; A496-P533 HydrophobicContact CB-CG 4.04Å
497	I	94.8	Very high	92.7	Very high	47 Å²	47	16.2 Å²	16.2	24%	0.241	8%	0.077	C	C	.	.	H	α-helix	trans	-64.2	-46.3	174.2	-68.3	167.9	0	0	0	110.9	L493 I494 E495 V499 W501 F502 P533	L493-I497 HydrophobicContact CD1-CD1 3.85Å; L493-I497 HydrophobicContact CD1-CG1 4.41Å; L493-I497 HydrophobicContact CG-CD1 4.04Å; L493-I497 VanDerWaalsContact O-CG1 3.28Å; L493-I497 WeakPolarHBondContact O-CG1 3.45Å; L493-I497 PolarHBondContact O-N 3Å; I494-I497 PolarHBondContact O-N 3.31Å; E495-I497 VanDerWaalsContact C-N 3.29Å; E495-I497 PolarHBondContact O-N 2.89Å; I497-V499 PolarHBondContact O-N 3.17Å; I497-W501 HydrophobicContact CG2-CB 4.49Å; I497-W501 VanDerWaalsContact O-CB 3.31Å; I497-W501 WeakPolarHBondContact O-CB 3.41Å; I497-W501 PolarHBondContact O-N 3.33Å; I497-F502 HydrophobicContact CG2-CD2 4.03Å; I497-F502 HydrophobicContact CG2-CE2 3.79Å; I497-F502 PolarHBondContact O-N 2.87Å; I497-P533 HydrophobicContact CG1-CB 4.28Å
498	G	94.1	Very high	92.9	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	8%	0.078	C	C	.	.	I	π-helix	trans	-60	-44.6	-179.9	0	0	0	0	0	112.7	I494 E495 F502 Y503	I494-G498 PolarHBondContact O-N 2.86Å; E495-G498 PolarHBondContact O-N 3.5Å; E495-G498 VanDerWaalsContact O-N 3.12Å; G498-F502 WeakPolarHBondContact O-CB 3.26Å; G498-F502 PolarHBondContact O-N 2.81Å; G498-Y503 PolarHBondContact O-N 2.8Å
499	V	95.1	Very high	93.1	Very high	1 Å²	1	16.3 Å²	16.3	1%	0.006	8%	0.077	C	C	.	.	I	π-helix	trans	-75.5	-50.9	179.1	178.4	0	0	0	0	111.3	M120 L124 W136 I138 E495 I497 Y503 G504 F508	M120-V499 HydrophobicContact CG-CG1 4.11Å; M120-V499 HydrophobicContact SD-CB 3.93Å; M120-V499 HydrophobicContact SD-CG1 3.96Å; M120-V499 HydrophobicContact SD-CG2 4.32Å; L124-V499 HydrophobicContact CD1-CG2 4.44Å; L124-V499 HydrophobicContact CD2-CG2 4.01Å; W136-V499 HydrophobicContact CH2-CG2 4.26Å; I138-V499 HydrophobicContact CD1-CG2 4.17Å; E495-V499 HydrophobicContact CG-CG2 4.49Å; E495-V499 WeakPolarHBondContact O-CG2 3.4Å; E495-V499 PolarHBondContact O-N 3.1Å; I497-V499 PolarHBondContact O-N 3.17Å; V499-Y503 WeakPolarHBondContact O-CB 3.37Å; V499-G504 PolarHBondContact O-N 2.77Å; V499-F508 HydrophobicContact CG1-CD1 4.23Å; V499-F508 HydrophobicContact CG1-CD2 4.09Å; V499-F508 HydrophobicContact CG1-CE1 4.42Å; V499-F508 HydrophobicContact CG1-CE2 4.29Å; V499-F508 HydrophobicContact CG1-CG 4.05Å; V499-F508 HydrophobicContact CG1-CZ 4.44Å
500	A	93.6	Very high	93.4	Very high	4 Å²	4	19.4 Å²	19.4	3%	0.033	9%	0.091	C	C	.	.	I	π-helix	trans	-76.4	-39.8	-171.2	0	0	0	0	0	113.3	A496 G504 V505 W528 K529	A496-A500 WeakPolarHBondContact O-CB 3.47Å; A496-A500 PolarHBondContact O-N 3.45Å; A500-G504 CarbonylContact O-C 3.58Å; A500-G504 WeakPolarHBondContact O-CA 3.38Å; A500-V505 HydrophobicContact CB-CG2 3.58Å; A500-V505 WeakPolarHBondContact O-CG2 3.22Å; A500-V505 PolarHBondContact O-N 3.39Å; A500-W528 HydrophobicContact CB-CB 4.29Å; A500-W528 WeakPolarHBondContact CB-O 3.33Å; A500-K529 HydrophobicContact CB-CB 4.45Å
501	W	92.6	Very high	93.5	Very high	69 Å²	69	17.7 Å²	17.7	26%	0.261	8%	0.084	S	C	.	.	I	π-helix	trans	-97.8	-46.7	-173.6	-70.2	88	0	0	0	113.2	I497 K529 F530 H620 W621	I497-W501 HydrophobicContact CG2-CB 4.49Å; I497-W501 VanDerWaalsContact O-CB 3.31Å; I497-W501 WeakPolarHBondContact O-CB 3.41Å; I497-W501 PolarHBondContact O-N 3.33Å; W501-K529 HydrophobicContact CD2-CG 4.33Å; W501-K529 HydrophobicContact CH2-CG 4.49Å; W501-K529 HydrophobicContact CZ2-CG 3.88Å; W501-K529 PolarHBondContact NE1-O 2.99Å; W501-F530 HydrophobicContact CH2-CD1 4.34Å; W501-F530 AromaticContact CH2-CE1 3.53Å; W501-F530 HydrophobicContact CH2-CE1 3.53Å; W501-F530 HydrophobicContact CH2-CZ 4.09Å; W501-F530 AromaticContact CZ2-CD1 3.81Å; W501-F530 HydrophobicContact CZ2-CD1 3.81Å; W501-F530 AromaticContact CZ2-CE1 3.45Å; W501-F530 HydrophobicContact CZ2-CE1 3.45Å; W501-F530 VanDerWaalsContact CZ2-CE1 3.45Å; W501-F530 HydrophobicContact CZ2-CZ 4.21Å; W501-H620 PolarHBondContact O-NE2 3.1Å; W501-W621 HydrophobicContact CB-CZ3 4.09Å; W501-W621 AromaticContact CE3-CE3 3.81Å; W501-W621 HydrophobicContact CE3-CE3 3.81Å; W501-W621 HydrophobicContact CE3-CZ3 4.21Å; W501-W621 HydrophobicContact CZ3-CE3 4.43Å
502	F	91.9	Very high	93.6	Very high	48 Å²	48	17.7 Å²	17.7	21%	0.211	8%	0.084	C	C	.	.	I	π-helix	trans	-82.9	-52	-176	-72.7	-98.2	0	0	0	112.2	F142 I497 G498 I599 H620 W621	F142-F502 HydrophobicContact CD2-CG 4.46Å; F142-F502 HydrophobicContact CE2-CB 4.06Å; F142-F502 AromaticContact CE2-CD1 3.86Å; F142-F502 HydrophobicContact CE2-CD1 3.86Å; F142-F502 AromaticContact CE2-CD2 3.41Å; F142-F502 HydrophobicContact CE2-CD2 3.41Å; F142-F502 VanDerWaalsContact CE2-CD2 3.41Å; F142-F502 HydrophobicContact CE2-CE1 4.1Å; F142-F502 AromaticContact CE2-CE2 3.68Å; F142-F502 HydrophobicContact CE2-CE2 3.68Å; F142-F502 AromaticContact CE2-CG 3.51Å; F142-F502 HydrophobicContact CE2-CG 3.51Å; F142-F502 HydrophobicContact CE2-CZ 4.01Å; F142-F502 AromaticContact CZ-CD2 3.78Å; F142-F502 HydrophobicContact CZ-CD2 3.78Å; F142-F502 HydrophobicContact CZ-CE1 4.34Å; F142-F502 AromaticContact CZ-CE2 3.56Å; F142-F502 HydrophobicContact CZ-CE2 3.56Å; F142-F502 HydrophobicContact CZ-CG 4.26Å; F142-F502 AromaticContact CZ-CZ 3.86Å; F142-F502 HydrophobicContact CZ-CZ 3.86Å; I497-F502 HydrophobicContact CG2-CD2 4.03Å; I497-F502 HydrophobicContact CG2-CE2 3.79Å; I497-F502 PolarHBondContact O-N 2.87Å; G498-F502 WeakPolarHBondContact O-CB 3.26Å; G498-F502 PolarHBondContact O-N 2.81Å; F502-I599 HydrophobicContact CD1-CB 4.46Å; F502-I599 HydrophobicContact CD1-CG2 4.07Å; F502-I599 HydrophobicContact CE1-CG2 4.3Å; F502-H620 PolarHBondContact O-CE1 2.72Å; F502-H620 PolarHBondContact O-NE2 3.08Å; F502-W621 HydrophobicContact CD1-CH2 4.2Å; F502-W621 HydrophobicContact CE1-CH2 4.21Å; F502-W621 HydrophobicContact CG-CH2 4.48Å; F502-W621 HydrophobicContact CZ-CH2 4.49Å
503	Y	92.3	Very high	93.7	Very high	4 Å²	4	21.5 Å²	21.5	2%	0.016	10%	0.102	C	C	.	.	I	π-helix	trans	-69.8	-36.9	174.1	-175.5	-112.8	0	0	0	111.9	I138 G498 V499 R507 F508 D511 P601	I138-Y503 HydrophobicContact CB-CD2 3.62Å; I138-Y503 HydrophobicContact CB-CE2 3.76Å; I138-Y503 HydrophobicContact CB-CG 4.19Å; I138-Y503 HydrophobicContact CD1-CD1 4.45Å; I138-Y503 HydrophobicContact CD1-CD2 4.4Å; I138-Y503 HydrophobicContact CD1-CG 4.09Å; I138-Y503 HydrophobicContact CG2-CD2 4.24Å; I138-Y503 HydrophobicContact CG2-CE2 3.89Å; G498-Y503 PolarHBondContact O-N 2.8Å; V499-Y503 WeakPolarHBondContact O-CB 3.37Å; Y503-R507 HydrophobicContact CE1-CB 4.33Å; Y503-R507 HydrophobicContact CE1-CG 3.82Å; Y503-R507 HydrophobicContact CE2-CG 4.21Å; Y503-R507 WeakPolarHBondContact OH-CD 3.22Å; Y503-F508 HydrophobicContact CD1-CB 4.2Å; Y503-F508 HydrophobicContact CE1-CB 4.23Å; Y503-F508 HydrophobicContact CE1-CD2 4.35Å; Y503-D511 WeakPolarHBondContact CE1-OD2 3.25Å; Y503-D511 VanDerWaalsContact CZ-OD2 3.25Å; Y503-D511 PolarHBondContact OH-OD2 3.27Å; Y503-P601 HydrophobicContact CD2-CG 4.06Å; Y503-P601 HydrophobicContact CE2-CG 3.85Å
504	G	92.1	Very high	93.7	Very high	4 Å²	4	28.5 Å²	28.5	4%	0.041	13%	0.128	C	C	.	.	I	π-helix	trans	98.2	125.7	171.6	0	0	0	0	0	112.6	V499 A500 D506 R507 F508	V499-G504 PolarHBondContact O-N 2.77Å; A500-G504 CarbonylContact O-C 3.58Å; A500-G504 WeakPolarHBondContact O-CA 3.38Å; G504-D506 VanDerWaalsContact C-N 3.27Å; G504-D506 PolarHBondContact O-N 2.96Å; G504-R507 PolarHBondContact O-N 3.43Å; G504-F508 PolarHBondContact O-N 2.87Å
505	V	92.4	Very high	93.7	Very high	4 Å²	4	27.5 Å²	27.5	2%	0.024	12%	0.122	C	C	.	.	H	α-helix	trans	-58.6	-35.4	-179.6	175.5	0	0	0	0	113.2	A500 F508 S509 R525 K529 I624	A500-V505 HydrophobicContact CB-CG2 3.58Å; A500-V505 WeakPolarHBondContact O-CG2 3.22Å; A500-V505 PolarHBondContact O-N 3.39Å; V505-F508 PolarHBondContact O-N 3.21Å; V505-S509 VanDerWaalsContact O-CB 3.27Å; V505-S509 WeakPolarHBondContact O-CB 3.42Å; V505-S509 PolarHBondContact O-N 3.14Å; V505-S509 PolarHBondContact O-OG 2.89Å; V505-R525 HydrophobicContact CG1-CB 3.6Å; V505-R525 HydrophobicContact CG1-CG 3.58Å; V505-K529 HydrophobicContact CG2-CB 4Å; V505-K529 HydrophobicContact CG2-CD 4.35Å; V505-K529 HydrophobicContact CG2-CG 4.37Å; V505-I624 WeakPolarHBondContact CG1-OXT 3.16Å
506	D	90.6	Very high	93.5	Very high	57 Å²	57	28.9 Å²	28.9	31%	0.305	13%	0.129	S	C	.	.	H	α-helix	trans	-60.9	-48.5	176.7	-81.5	11.6	0	0	0	112	G504 S509 E510 R525 A623	G504-D506 VanDerWaalsContact C-N 3.27Å; G504-D506 PolarHBondContact O-N 2.96Å; D506-S509 WeakPolarHBondContact O-CB 3.42Å; D506-S509 PolarHBondContact O-N 3.11Å; D506-E510 WeakPolarHBondContact O-CG 3.37Å; D506-E510 PolarHBondContact O-N 3.46Å; D506-R525 IonicContact OD1-CZ 3.82Å; D506-R525 IonicContact OD1-NH2 2.67Å; D506-R525 PolarHBondContact OD1-NH2 2.84Å; D506-A623 VanDerWaalsContact CG-CB 3.48Å; D506-A623 WeakPolarHBondContact OD2-CB 3.29Å
507	R	90.6	Very high	93.4	Very high	18 Å²	18	31.9 Å²	31.9	7%	0.068	16%	0.16	C	C	.	.	H	α-helix	trans	-64.1	-45.8	178.9	-178.9	179.9	-70.9	-165.2	-17.9	110.6	Y503 G504 S509 E510 D511 E604	Y503-R507 HydrophobicContact CE1-CB 4.33Å; Y503-R507 HydrophobicContact CE1-CG 3.82Å; Y503-R507 HydrophobicContact CE2-CG 4.21Å; Y503-R507 WeakPolarHBondContact OH-CD 3.22Å; G504-R507 PolarHBondContact O-N 3.43Å; R507-S509 PolarHBondContact O-N 3.09Å; R507-E510 WeakPolarHBondContact O-CB 3.39Å; R507-E510 PolarHBondContact O-N 3.04Å; R507-E510 VanDerWaalsContact O-N 3.12Å; R507-D511 PolarHBondContact O-N 2.85Å; R507-E604 IonicContact CZ-OE1 3.18Å; R507-E604 IonicContact CZ-OE2 2.76Å; R507-E604 IonicContact NH1-OE1 2.79Å; R507-E604 IonicContact NH1-OE2 2.92Å; R507-E604 PolarHBondContact NH1-OE2 2.84Å; R507-E604 IonicContact NH2-OE1 2.82Å; R507-E604 PolarHBondContact NH2-OE1 3.39Å; R507-E604 IonicContact NH2-OE2 2.75Å; R507-E604 PolarHBondContact NH2-OE2 2.86Å
508	F	94.6	Very high	93.3	Very high	4 Å²	4	33.5 Å²	33.5	2%	0.018	17%	0.166	C	C	.	.	H	α-helix	trans	-60.5	-36	176	-171.1	-118.6	0	0	0	112.2	M120 A123 L124 V499 Y503 G504 V505 D511 I512 W528	M120-F508 HydrophobicContact CG-CE1 3.95Å; M120-F508 HydrophobicContact CG-CZ 3.97Å; A123-F508 HydrophobicContact CB-CE2 4.41Å; A123-F508 HydrophobicContact CB-CZ 3.79Å; L124-F508 HydrophobicContact CB-CE2 4.19Å; L124-F508 HydrophobicContact CB-CZ 4.46Å; L124-F508 HydrophobicContact CD1-CE2 4.21Å; V499-F508 HydrophobicContact CG1-CD1 4.23Å; V499-F508 HydrophobicContact CG1-CD2 4.09Å; V499-F508 HydrophobicContact CG1-CE1 4.42Å; V499-F508 HydrophobicContact CG1-CE2 4.29Å; V499-F508 HydrophobicContact CG1-CG 4.05Å; V499-F508 HydrophobicContact CG1-CZ 4.44Å; Y503-F508 HydrophobicContact CD1-CB 4.2Å; Y503-F508 HydrophobicContact CE1-CB 4.23Å; Y503-F508 HydrophobicContact CE1-CD2 4.35Å; G504-F508 PolarHBondContact O-N 2.87Å; V505-F508 PolarHBondContact O-N 3.21Å; F508-D511 PolarHBondContact O-N 3.21Å; F508-I512 HydrophobicContact CD1-CD1 3.89Å; F508-I512 HydrophobicContact CE1-CD1 3.6Å; F508-I512 HydrophobicContact CZ-CD1 3.98Å; F508-I512 WeakPolarHBondContact O-CG1 3.47Å; F508-I512 PolarHBondContact O-N 2.88Å; F508-W528 AromaticContact CD1-CE3 3.98Å; F508-W528 HydrophobicContact CD1-CE3 3.98Å; F508-W528 HydrophobicContact CD1-CH2 4.1Å; F508-W528 AromaticContact CD1-CZ3 3.66Å; F508-W528 HydrophobicContact CD1-CZ3 3.66Å; F508-W528 HydrophobicContact CE1-CE3 4.13Å; F508-W528 AromaticContact CE1-CH2 3.68Å; F508-W528 HydrophobicContact CE1-CH2 3.68Å; F508-W528 HydrophobicContact CE1-CZ2 4.06Å; F508-W528 AromaticContact CE1-CZ3 3.72Å; F508-W528 HydrophobicContact CE1-CZ3 3.72Å
509	S	94.2	Very high	93.2	Very high	1 Å²	1	38.3 Å²	38.3	1%	0.007	19%	0.186	C	C	.	.	H	α-helix	trans	-68.2	-37.7	175	-61.4	0	0	0	0	112.5	V505 D506 R507 I512 E513 R525	V505-S509 VanDerWaalsContact O-CB 3.27Å; V505-S509 WeakPolarHBondContact O-CB 3.42Å; V505-S509 PolarHBondContact O-N 3.14Å; V505-S509 PolarHBondContact O-OG 2.89Å; D506-S509 WeakPolarHBondContact O-CB 3.42Å; D506-S509 PolarHBondContact O-N 3.11Å; R507-S509 PolarHBondContact O-N 3.09Å; S509-I512 PolarHBondContact O-N 3.2Å; S509-E513 WeakPolarHBondContact O-CB 3.42Å; S509-E513 PolarHBondContact O-N 3.42Å; S509-R525 PolarHBondContact OG-NE 3.43Å
510	E	94.3	Very high	93.1	Very high	67 Å²	67	38.5 Å²	38.5	31%	0.313	19%	0.188	S	C	.	.	H	α-helix	trans	-65.9	-39.6	171.9	-71	174.6	-175.4	0	0	111.9	D506 R507 I512 E513 R514	D506-E510 WeakPolarHBondContact O-CG 3.37Å; D506-E510 PolarHBondContact O-N 3.46Å; R507-E510 WeakPolarHBondContact O-CB 3.39Å; R507-E510 PolarHBondContact O-N 3.04Å; R507-E510 VanDerWaalsContact O-N 3.12Å; E510-I512 VanDerWaalsContact C-N 3.31Å; E510-I512 PolarHBondContact O-N 3.08Å; E510-E513 WeakPolarHBondContact O-CB 3.45Å; E510-E513 PolarHBondContact O-N 3.5Å; E510-R514 VanDerWaalsContact O-CG 3.31Å; E510-R514 WeakPolarHBondContact O-CG 3.43Å; E510-R514 PolarHBondContact O-N 2.66Å
511	D	94.6	Very high	93.1	Very high	4 Å²	4	40.3 Å²	40.3	2%	0.021	21%	0.207	C	C	.	.	H	α-helix	trans	-62.5	-41.4	175.7	-65.3	-27.5	0	0	0	111.3	Y127 Y503 R507 F508 R514 M515	Y127-D511 HydrophobicContact CD1-CB 3.97Å; Y127-D511 HydrophobicContact CD2-CB 3.83Å; Y127-D511 HydrophobicContact CE1-CB 3.75Å; Y127-D511 WeakPolarHBondContact CE1-OD1 3.44Å; Y127-D511 HydrophobicContact CE2-CB 3.63Å; Y127-D511 HydrophobicContact CG-CB 3.99Å; Y127-D511 PolarHBondContact OH-OD1 2.95Å; Y503-D511 WeakPolarHBondContact CE1-OD2 3.25Å; Y503-D511 VanDerWaalsContact CZ-OD2 3.25Å; Y503-D511 PolarHBondContact OH-OD2 3.27Å; R507-D511 PolarHBondContact O-N 2.85Å; F508-D511 PolarHBondContact O-N 3.21Å; D511-R514 PolarHBondContact O-N 2.91Å; D511-R514 IonicContact OD1-NH1 3.85Å; D511-M515 WeakPolarHBondContact O-CG 3.48Å; D511-M515 PolarHBondContact O-N 3.36Å; D511-M515 VanDerWaalsContact O-N 3.13Å
512	I	95.3	Very high	93.1	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-64.9	-42.2	174	-71.7	169.2	0	0	0	111.7	Y119 A123 F508 S509 E510 R514 M515 M516 P520 W528	Y119-I512 WeakPolarHBondContact OH-CG2 3.49Å; A123-I512 HydrophobicContact CB-CD1 3.99Å; A123-I512 HydrophobicContact CB-CG1 3.99Å; F508-I512 HydrophobicContact CD1-CD1 3.89Å; F508-I512 HydrophobicContact CE1-CD1 3.6Å; F508-I512 HydrophobicContact CZ-CD1 3.98Å; F508-I512 WeakPolarHBondContact O-CG1 3.47Å; F508-I512 PolarHBondContact O-N 2.88Å; S509-I512 PolarHBondContact O-N 3.2Å; E510-I512 VanDerWaalsContact C-N 3.31Å; E510-I512 PolarHBondContact O-N 3.08Å; I512-R514 VanDerWaalsContact C-N 3.3Å; I512-R514 PolarHBondContact O-N 3.37Å; I512-M515 HydrophobicContact CB-CE 4.42Å; I512-M515 HydrophobicContact CG1-CE 3.93Å; I512-M515 PolarHBondContact O-N 3.27Å; I512-M515 VanDerWaalsContact O-N 3.14Å; I512-M516 HydrophobicContact CG2-CE 3.31Å; I512-M516 PolarHBondContact O-N 2.94Å; I512-P520 HydrophobicContact CB-CG 3.95Å; I512-P520 HydrophobicContact CD1-CG 3.57Å; I512-P520 HydrophobicContact CG1-CG 4.36Å; I512-P520 HydrophobicContact CG2-CG 3.75Å; I512-W528 HydrophobicContact CD1-CH2 3.68Å; I512-W528 HydrophobicContact CD1-CZ3 4.15Å
513	E	95.4	Very high	93.2	Very high	79 Å²	79	44.3 Å²	44.3	37%	0.369	23%	0.229	S	C	.	.	H	α-helix	trans	-61.5	-38.9	175.4	-177.3	-179.1	-139.5	0	0	111.6	S509 E510 M515 G517 F518 K519	S509-E513 WeakPolarHBondContact O-CB 3.42Å; S509-E513 PolarHBondContact O-N 3.42Å; E510-E513 WeakPolarHBondContact O-CB 3.45Å; E510-E513 PolarHBondContact O-N 3.5Å; E513-M515 VanDerWaalsContact C-N 3.3Å; E513-M515 PolarHBondContact O-N 2.91Å; E513-G517 WeakPolarHBondContact O-CA 3.4Å; E513-G517 PolarHBondContact O-N 3.16Å; E513-F518 WeakPolarHBondContact CA-O 3.19Å; E513-K519 HydrophobicContact CB-CG 3.8Å; E513-K519 VanDerWaalsContact CD-CG 3.49Å; E513-K519 HydrophobicContact CG-CG 4Å; E513-K519 WeakPolarHBondContact OE1-CE 3.39Å; E513-K519 WeakPolarHBondContact OE2-CE 3.46Å; E513-K519 IonicContact OE2-NZ 3.73Å
514	R	94.6	Very high	93.4	Very high	158 Å²	158	45.4 Å²	45.4	60%	0.596	23%	0.233	S	C	*	.	H	α-helix	trans	-64.5	-32.9	174.6	-71.3	171.8	-172.3	172	5.4	112.9	Y127 E510 D511 I512	Y127-R514 PolarHBondContact OH-NH1 3.26Å; E510-R514 VanDerWaalsContact O-CG 3.31Å; E510-R514 WeakPolarHBondContact O-CG 3.43Å; E510-R514 PolarHBondContact O-N 2.66Å; D511-R514 PolarHBondContact O-N 2.91Å; D511-R514 IonicContact OD1-NH1 3.85Å; I512-R514 VanDerWaalsContact C-N 3.3Å; I512-R514 PolarHBondContact O-N 3.37Å
515	M	93.9	Very high	93.5	Very high	7 Å²	7	47.4 Å²	47.4	3%	0.034	24%	0.239	C	C	.	.	H	α-helix	trans	-76.7	-48.5	177.4	-71.8	-172.7	-71.3	0	0	112.8	A123 Q126 Y127 F342 N343 D511 I512 E513	A123-M515 HydrophobicContact CB-CE 4.26Å; Q126-M515 HydrophobicContact CB-SD 4.18Å; Q126-M515 HydrophobicContact CG-SD 4.06Å; Y127-M515 VanDerWaalsContact CA-SD 3.51Å; Y127-M515 VanDerWaalsContact CB-SD 3.59Å; Y127-M515 HydrophobicContact CD2-CE 4.18Å; Y127-M515 HydrophobicContact CD2-CG 3.76Å; Y127-M515 HydrophobicContact CD2-SD 3.91Å; Y127-M515 HydrophobicContact CG-CE 4.39Å; Y127-M515 HydrophobicContact CG-SD 4.26Å; F342-M515 HydrophobicContact CD1-CG 4.38Å; F342-M515 HydrophobicContact CD2-CG 4.25Å; F342-M515 HydrophobicContact CE1-CG 3.98Å; F342-M515 HydrophobicContact CE2-CG 3.84Å; F342-M515 HydrophobicContact CZ-CG 3.69Å; F342-M515 WeakPolarHBondContact O-CB 3.5Å; N343-M515 WeakPolarHBondContact CA-O 3.32Å; D511-M515 WeakPolarHBondContact O-CG 3.48Å; D511-M515 PolarHBondContact O-N 3.36Å; D511-M515 VanDerWaalsContact O-N 3.13Å; I512-M515 HydrophobicContact CB-CE 4.42Å; I512-M515 HydrophobicContact CG1-CE 3.93Å; I512-M515 PolarHBondContact O-N 3.27Å; I512-M515 VanDerWaalsContact O-N 3.14Å; E513-M515 VanDerWaalsContact C-N 3.3Å; E513-M515 PolarHBondContact O-N 2.91Å
516	M	91.9	Very high	93.6	Very high	31 Å²	31	50.3 Å²	50.3	15%	0.153	25%	0.254	C	S	.	.	H	α-helix	trans	-111.2	-9.6	-166.5	-59.6	-164.3	-69.6	0	0	114.4	Y119 I512 F518	Y119-M516 HydrophobicContact CE2-CE 4.36Å; Y119-M516 WeakPolarHBondContact OH-CE 3.34Å; I512-M516 HydrophobicContact CG2-CE 3.31Å; I512-M516 PolarHBondContact O-N 2.94Å; M516-F518 HydrophobicContact CB-CD1 3.95Å; M516-F518 HydrophobicContact CB-CE1 3.6Å; M516-F518 HydrophobicContact CB-CZ 4.11Å; M516-F518 HydrophobicContact CE-CE1 4.2Å; M516-F518 HydrophobicContact CE-CE2 3.82Å; M516-F518 HydrophobicContact CE-CZ 3.52Å; M516-F518 WeakPolarHBondContact O-CD1 3.49Å; M516-F518 HydrophobicContact SD-CE1 4.19Å; M516-F518 HydrophobicContact SD-CZ 3.88Å
517	G	91.7	Very high	93.8	Very high	63 Å²	63	47.8 Å²	47.8	65%	0.649	24%	0.241	S	C	*	.	S	Bend	trans	83.3	3.9	-178.5	0	0	0	0	0	115.2	E513	E513-G517 WeakPolarHBondContact O-CA 3.4Å; E513-G517 PolarHBondContact O-N 3.16Å
518	F	92.5	Very high	94.1	Very high	81 Å²	81	47 Å²	47	36%	0.355	24%	0.238	S	C	.	.	S	Bend	trans	-141.4	144.8	176.9	63.6	-91.9	0	0	0	111.8	Y347 E513 M516	Y347-F518 HydrophobicContact CD1-CZ 4.29Å; Y347-F518 HydrophobicContact CG-CZ 4.36Å; E513-F518 WeakPolarHBondContact CA-O 3.19Å; M516-F518 HydrophobicContact CB-CD1 3.95Å; M516-F518 HydrophobicContact CB-CE1 3.6Å; M516-F518 HydrophobicContact CB-CZ 4.11Å; M516-F518 HydrophobicContact CE-CE1 4.2Å; M516-F518 HydrophobicContact CE-CE2 3.82Å; M516-F518 HydrophobicContact CE-CZ 3.52Å; M516-F518 WeakPolarHBondContact O-CD1 3.49Å; M516-F518 HydrophobicContact SD-CE1 4.19Å; M516-F518 HydrophobicContact SD-CZ 3.88Å
519	K	92.4	Very high	94	Very high	100 Å²	100	47.1 Å²	47.1	44%	0.435	24%	0.239	S	C	.	.	P	Polyproline II helix	trans	-75.8	143.9	174.4	-71.2	-171.8	-179.8	-167.5	0	111.6	E513	E513-K519 HydrophobicContact CB-CG 3.8Å; E513-K519 VanDerWaalsContact CD-CG 3.49Å; E513-K519 HydrophobicContact CG-CG 4Å; E513-K519 WeakPolarHBondContact OE1-CE 3.39Å; E513-K519 WeakPolarHBondContact OE2-CE 3.46Å; E513-K519 IonicContact OE2-NZ 3.73Å
520	P	93.6	Very high	94	Very high	6 Å²	6	51.2 Å²	51.2	4%	0.039	26%	0.256	C	S	.	.	P	Polyproline II helix	trans	-55.8	138.5	167.6	-22.4	32.2	0	0	0	111.7	I512 W524 R525 W528	I512-P520 HydrophobicContact CB-CG 3.95Å; I512-P520 HydrophobicContact CD1-CG 3.57Å; I512-P520 HydrophobicContact CG1-CG 4.36Å; I512-P520 HydrophobicContact CG2-CG 3.75Å; P520-W524 HydrophobicContact CB-CB 4.18Å; P520-R525 HydrophobicContact CB-CG 4.47Å; P520-W528 HydrophobicContact CB-CH2 4.22Å; P520-W528 HydrophobicContact CB-CZ3 4.15Å; P520-W528 HydrophobicContact CG-CH2 4.15Å; P520-W528 HydrophobicContact CG-CZ3 4.13Å
521	G	92.8	Very high	94	Very high	42 Å²	42	50.8 Å²	50.8	43%	0.433	26%	0.258	S	S	.	.	P	Polyproline II helix	trans	-63	163.1	174.1	0	0	0	0	0	113	Y523 W524 R525	G521-Y523 PolarHBondContact O-N 3.37Å; G521-Y523 VanDerWaalsContact O-N 3.14Å; G521-W524 PolarHBondContact O-N 2.9Å; G521-W524 VanDerWaalsContact O-N 3.15Å; G521-R525 PolarHBondContact O-N 3.5Å
522	L	93.3	Very high	93.9	Very high	106 Å²	106	50.6 Å²	50.6	56%	0.555	26%	0.257	S	S	*	.	H	α-helix	trans	-55.5	-34.1	-178.9	-174.6	66.3	0	0	0	113	W524 R525 L526 I624	L522-W524 PolarHBondContact O-N 3.45Å; L522-R525 PolarHBondContact O-N 3.2Å; L522-L526 HydrophobicContact CD1-CD1 4.37Å; L522-L526 HydrophobicContact CD1-CG 4.24Å; L522-L526 HydrophobicContact CD2-CD1 4.24Å; L522-L526 HydrophobicContact CG-CD1 3.83Å; L522-L526 HydrophobicContact CG-CG 4.14Å; L522-L526 WeakPolarHBondContact O-CB 3.29Å; L522-L526 WeakPolarHBondContact O-CG 3.16Å; L522-L526 PolarHBondContact O-N 2.91Å; L522-I624 HydrophobicContact CD1-CG2 3.78Å
523	Y	95.1	Very high	93.8	Very high	95 Å²	95	51.1 Å²	51.1	37%	0.373	26%	0.26	S	S	.	.	H	α-helix	trans	-51.7	-54.5	175.3	170.4	-100.6	0	0	0	112.6	V111 G521 R525 L526 C527	V111-Y523 VanDerWaalsContact C-OH 3.24Å; V111-Y523 HydrophobicContact CG1-CE2 4.4Å; V111-Y523 WeakPolarHBondContact CG1-OH 3.49Å; V111-Y523 PolarHBondContact O-OH 3.21Å; G521-Y523 PolarHBondContact O-N 3.37Å; G521-Y523 VanDerWaalsContact O-N 3.14Å; Y523-R525 VanDerWaalsContact C-N 3.33Å; Y523-R525 PolarHBondContact O-N 3.06Å; Y523-L526 PolarHBondContact O-N 2.99Å; Y523-C527 WeakPolarHBondContact O-CB 3.15Å; Y523-C527 PolarHBondContact O-N 3Å; Y523-C527 PolarHBondContact O-SG 2.92Å
524	W	95.2	Very high	93.7	Very high	26 Å²	26	50.3 Å²	50.3	10%	0.098	27%	0.268	C	S	.	.	H	α-helix	trans	-63.6	-42.1	-178	-60.5	105.2	0	0	0	111.5	M115 P116 Y119 Y347 P520 G521 L522 C527 W528	M115-W524 HydrophobicContact CG-CH2 3.89Å; M115-W524 HydrophobicContact CG-CZ3 4.19Å; M115-W524 HydrophobicContact SD-CH2 3.81Å; P116-W524 HydrophobicContact CB-CE3 4.04Å; P116-W524 HydrophobicContact CB-CZ3 4.14Å; P116-W524 HydrophobicContact CG-CE3 4.04Å; P116-W524 HydrophobicContact CG-CZ3 3.86Å; Y119-W524 AromaticContact CD1-CD2 3.94Å; Y119-W524 HydrophobicContact CD1-CD2 3.94Å; Y119-W524 AromaticContact CD1-CE3 3.82Å; Y119-W524 HydrophobicContact CD1-CE3 3.82Å; Y119-W524 HydrophobicContact CD1-CG 4.42Å; Y119-W524 HydrophobicContact CD1-CZ3 4.19Å; Y119-W524 HydrophobicContact CE1-CD2 4.29Å; Y119-W524 HydrophobicContact CE1-CG 4.37Å; Y347-W524 HydrophobicContact CD2-CZ2 4.45Å; Y347-W524 AromaticContact CE2-CE2 3.73Å; Y347-W524 AromaticContact CE2-CZ2 3.57Å; Y347-W524 HydrophobicContact CE2-CZ2 3.57Å; Y347-W524 AromaticContact CE2-NE1 3.63Å; P520-W524 HydrophobicContact CB-CB 4.18Å; G521-W524 PolarHBondContact O-N 2.9Å; G521-W524 VanDerWaalsContact O-N 3.15Å; L522-W524 PolarHBondContact O-N 3.45Å; W524-C527 PolarHBondContact O-N 2.92Å; W524-W528 HydrophobicContact CB-CD2 4.47Å; W524-W528 HydrophobicContact CB-CE3 4.39Å; W524-W528 HydrophobicContact CB-CH2 4.03Å; W524-W528 HydrophobicContact CB-CZ2 4.12Å; W524-W528 HydrophobicContact CB-CZ3 4.16Å; W524-W528 VanDerWaalsContact O-CD2 3.22Å; W524-W528 PolarHBondContact O-N 3.26Å
525	R	94.6	Very high	93.4	Very high	47 Å²	47	44.2 Å²	44.2	18%	0.177	25%	0.245	C	C	.	.	H	α-helix	trans	-63.1	-43.5	-179.6	-65.1	173.3	73.8	-168.3	5.1	111.8	V505 D506 S509 P520 G521 L522 Y523 K529 I624	V505-R525 HydrophobicContact CG1-CB 3.6Å; V505-R525 HydrophobicContact CG1-CG 3.58Å; D506-R525 IonicContact OD1-CZ 3.82Å; D506-R525 IonicContact OD1-NH2 2.67Å; D506-R525 PolarHBondContact OD1-NH2 2.84Å; S509-R525 PolarHBondContact OG-NE 3.43Å; P520-R525 HydrophobicContact CB-CG 4.47Å; G521-R525 PolarHBondContact O-N 3.5Å; L522-R525 PolarHBondContact O-N 3.2Å; Y523-R525 VanDerWaalsContact C-N 3.33Å; Y523-R525 PolarHBondContact O-N 3.06Å; R525-K529 WeakPolarHBondContact O-CB 3.33Å; R525-K529 PolarHBondContact O-N 3.43Å; R525-K529 VanDerWaalsContact O-N 3.08Å; R525-I624 HydrophobicContact CB-CG2 4.46Å; R525-I624 WeakPolarHBondContact CB-OXT 3.15Å; R525-I624 PolarHBondContact NE-O 3.42Å; R525-I624 PolarHBondContact NE-OXT 3.28Å; R525-I624 PolarHBondContact NH1-O 3.08Å; R525-I624 PolarHBondContact NH2-O 3.18Å; R525-I624 PolarHBondContact NH2-OXT 3.25Å
526	L	94.9	Very high	93.2	Very high	64 Å²	64	43.9 Å²	43.9	34%	0.335	24%	0.244	S	C	.	.	H	α-helix	trans	-66.7	-41.2	174.5	-73.2	174.1	0	0	0	112.5	L522 Y523 F530 V531 I624	L522-L526 HydrophobicContact CD1-CD1 4.37Å; L522-L526 HydrophobicContact CD1-CG 4.24Å; L522-L526 HydrophobicContact CD2-CD1 4.24Å; L522-L526 HydrophobicContact CG-CD1 3.83Å; L522-L526 HydrophobicContact CG-CG 4.14Å; L522-L526 WeakPolarHBondContact O-CB 3.29Å; L522-L526 WeakPolarHBondContact O-CG 3.16Å; L522-L526 PolarHBondContact O-N 2.91Å; Y523-L526 PolarHBondContact O-N 2.99Å; L526-F530 HydrophobicContact CD2-CD2 4.14Å; L526-F530 HydrophobicContact CD2-CE2 4.47Å; L526-F530 PolarHBondContact O-N 3.35Å; L526-V531 PolarHBondContact O-N 3.31Å; L526-I624 HydrophobicContact CD2-CD1 4.18Å; L526-I624 HydrophobicContact CD2-CG2 3.67Å; L526-I624 HydrophobicContact CG-CG2 4.14Å
527	C	95.1	Very high	93.2	Very high	5 Å²	5	46.5 Å²	46.5	3%	0.034	26%	0.258	C	S	.	.	I	π-helix	trans	-60	-51.9	176.2	-77.9	0	0	0	0	111.5	P116 Y523 W524 K529 V531 S532	P116-C527 HydrophobicContact CB-CB 3.78Å; P116-C527 HydrophobicContact CG-CB 3.73Å; Y523-C527 WeakPolarHBondContact O-CB 3.15Å; Y523-C527 PolarHBondContact O-N 3Å; Y523-C527 PolarHBondContact O-SG 2.92Å; W524-C527 PolarHBondContact O-N 2.92Å; C527-K529 PolarHBondContact O-N 3.49Å; C527-V531 PolarHBondContact O-N 2.89Å; C527-S532 WeakPolarHBondContact O-CB 3.42Å; C527-S532 PolarHBondContact O-N 3.29Å; C527-S532 PolarHBondContact O-OG 2.98Å; C527-S532 VanDerWaalsContact O-OG 3.05Å
528	W	95.3	Very high	93.1	Very high	2 Å²	2	48.6 Å²	48.6	1%	0.008	25%	0.25	C	C	.	.	I	π-helix	trans	-62.5	-40.9	-179.9	-62.5	-33.5	0	0	0	113.2	P116 Y119 M120 A500 F508 I512 P520 W524 P533	P116-W528 VanDerWaalsContact C-NE1 3.33Å; P116-W528 PolarHBondContact O-NE1 3.39Å; Y119-W528 AromaticContact CD1-CH2 3.92Å; Y119-W528 HydrophobicContact CD1-CH2 3.92Å; Y119-W528 AromaticContact CD1-CZ2 3.41Å; Y119-W528 HydrophobicContact CD1-CZ2 3.41Å; Y119-W528 VanDerWaalsContact CD1-CZ2 3.41Å; Y119-W528 AromaticContact CE1-CH2 3.66Å; Y119-W528 HydrophobicContact CE1-CH2 3.66Å; Y119-W528 AromaticContact CE1-CZ2 3.68Å; Y119-W528 HydrophobicContact CE1-CZ2 3.68Å; Y119-W528 HydrophobicContact CG-CZ2 4.19Å; M120-W528 HydrophobicContact CB-CZ2 4.38Å; A500-W528 HydrophobicContact CB-CB 4.29Å; A500-W528 WeakPolarHBondContact CB-O 3.33Å; F508-W528 AromaticContact CD1-CE3 3.98Å; F508-W528 HydrophobicContact CD1-CE3 3.98Å; F508-W528 HydrophobicContact CD1-CH2 4.1Å; F508-W528 AromaticContact CD1-CZ3 3.66Å; F508-W528 HydrophobicContact CD1-CZ3 3.66Å; F508-W528 HydrophobicContact CE1-CE3 4.13Å; F508-W528 AromaticContact CE1-CH2 3.68Å; F508-W528 HydrophobicContact CE1-CH2 3.68Å; F508-W528 HydrophobicContact CE1-CZ2 4.06Å; F508-W528 AromaticContact CE1-CZ3 3.72Å; F508-W528 HydrophobicContact CE1-CZ3 3.72Å; I512-W528 HydrophobicContact CD1-CH2 3.68Å; I512-W528 HydrophobicContact CD1-CZ3 4.15Å; P520-W528 HydrophobicContact CB-CH2 4.22Å; P520-W528 HydrophobicContact CB-CZ3 4.15Å; P520-W528 HydrophobicContact CG-CH2 4.15Å; P520-W528 HydrophobicContact CG-CZ3 4.13Å; W524-W528 HydrophobicContact CB-CD2 4.47Å; W524-W528 HydrophobicContact CB-CE3 4.39Å; W524-W528 HydrophobicContact CB-CH2 4.03Å; W524-W528 HydrophobicContact CB-CZ2 4.12Å; W524-W528 HydrophobicContact CB-CZ3 4.16Å; W524-W528 VanDerWaalsContact O-CD2 3.22Å; W524-W528 PolarHBondContact O-N 3.26Å; W528-P533 VanDerWaalsContact O-CD 3.32Å; W528-P533 WeakPolarHBondContact O-CD 3.48Å; W528-P533 WeakPolarHBondContact O-CG 3.33Å
529	K	93.8	Very high	92.8	Very high	6 Å²	6	44.9 Å²	44.9	3%	0.026	23%	0.233	C	C	.	.	I	π-helix	trans	-79.1	-43.2	-174.5	-163.7	168.6	-179.6	-177.4	0	113.6	A500 W501 V505 R525 C527 W621 A623 I624	A500-K529 HydrophobicContact CB-CB 4.45Å; W501-K529 HydrophobicContact CD2-CG 4.33Å; W501-K529 HydrophobicContact CH2-CG 4.49Å; W501-K529 HydrophobicContact CZ2-CG 3.88Å; W501-K529 PolarHBondContact NE1-O 2.99Å; V505-K529 HydrophobicContact CG2-CB 4Å; V505-K529 HydrophobicContact CG2-CD 4.35Å; V505-K529 HydrophobicContact CG2-CG 4.37Å; R525-K529 WeakPolarHBondContact O-CB 3.33Å; R525-K529 PolarHBondContact O-N 3.43Å; R525-K529 VanDerWaalsContact O-N 3.08Å; C527-K529 PolarHBondContact O-N 3.49Å; K529-W621 PolarHBondContact NZ-O 3.43Å; K529-A623 PolarHBondContact NZ-O 2.55Å; K529-I624 HydrophobicContact CD-CG1 4.48Å
530	F	94.1	Very high	92.5	Very high	86 Å²	86	40.8 Å²	40.8	38%	0.377	22%	0.217	S	C	.	.	I	π-helix	trans	-121.7	-55.1	-168.5	-62.1	-71.1	0	0	0	112.9	W501 L526 A534 I624	W501-F530 HydrophobicContact CH2-CD1 4.34Å; W501-F530 AromaticContact CH2-CE1 3.53Å; W501-F530 HydrophobicContact CH2-CE1 3.53Å; W501-F530 HydrophobicContact CH2-CZ 4.09Å; W501-F530 AromaticContact CZ2-CD1 3.81Å; W501-F530 HydrophobicContact CZ2-CD1 3.81Å; W501-F530 AromaticContact CZ2-CE1 3.45Å; W501-F530 HydrophobicContact CZ2-CE1 3.45Å; W501-F530 VanDerWaalsContact CZ2-CE1 3.45Å; W501-F530 HydrophobicContact CZ2-CZ 4.21Å; L526-F530 HydrophobicContact CD2-CD2 4.14Å; L526-F530 HydrophobicContact CD2-CE2 4.47Å; L526-F530 PolarHBondContact O-N 3.35Å; F530-A534 WeakPolarHBondContact O-CB 3.32Å; F530-A534 PolarHBondContact O-N 3.41Å; F530-I624 HydrophobicContact CE2-CD1 3.87Å; F530-I624 HydrophobicContact CE2-CG1 4.05Å
531	V	93.7	Very high	92.3	Very high	58 Å²	58	44.5 Å²	44.5	35%	0.352	24%	0.235	S	C	.	.	I	π-helix	trans	-67.9	-52.7	-167.1	-171.2	0	0	0	0	111.3	I112 L526 C527 F535	I112-V531 HydrophobicContact CB-CG1 3.88Å; I112-V531 HydrophobicContact CD1-CG1 4.33Å; I112-V531 HydrophobicContact CG1-CG1 4.44Å; I112-V531 HydrophobicContact CG2-CG1 4.47Å; L526-V531 PolarHBondContact O-N 3.31Å; C527-V531 PolarHBondContact O-N 2.89Å; V531-F535 WeakPolarHBondContact O-CB 3.43Å; V531-F535 PolarHBondContact O-N 3.16Å
532	S	92.9	Very high	92	Very high	0 Å²	0	42.9 Å²	42.9	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-65.1	-46.6	-178.2	-47.7	0	0	0	0	112.6	I112 C527 F535 L536	I112-S532 PolarHBondContact O-OG 2.52Å; C527-S532 WeakPolarHBondContact O-CB 3.42Å; C527-S532 PolarHBondContact O-N 3.29Å; C527-S532 PolarHBondContact O-OG 2.98Å; C527-S532 VanDerWaalsContact O-OG 3.05Å; S532-F535 PolarHBondContact O-N 2.99Å; S532-L536 WeakPolarHBondContact O-CB 3.49Å; S532-L536 WeakPolarHBondContact O-CG 3.34Å; S532-L536 PolarHBondContact O-N 3.33Å
533	P	93.6	Very high	91.4	Very high	11 Å²	11	39 Å²	39	7%	0.071	20%	0.199	C	C	.	.	H	α-helix	trans	-64.4	-43.4	177.9	-24.1	35.6	0	0	0	113.7	L493 A496 I497 W528 F535 L536 L537	L493-P533 HydrophobicContact CD1-CB 4.19Å; L493-P533 VanDerWaalsContact CD1-O 3.28Å; L493-P533 WeakPolarHBondContact CD1-O 3.46Å; A496-P533 HydrophobicContact CB-CG 4.04Å; I497-P533 HydrophobicContact CG1-CB 4.28Å; W528-P533 VanDerWaalsContact O-CD 3.32Å; W528-P533 WeakPolarHBondContact O-CD 3.48Å; W528-P533 WeakPolarHBondContact O-CG 3.33Å; P533-F535 VanDerWaalsContact C-N 3.28Å; P533-F535 PolarHBondContact O-N 3.22Å; P533-L536 PolarHBondContact O-N 3.24Å; P533-L537 VanDerWaalsContact O-CB 3.26Å; P533-L537 WeakPolarHBondContact O-CB 3.49Å; P533-L537 PolarHBondContact O-N 2.95Å
534	A	93.1	Very high	90.7	Very high	63 Å²	63	37.2 Å²	37.2	52%	0.521	20%	0.199	S	C	.	.	H	α-helix	trans	-62.7	-40.7	178.2	0	0	0	0	0	111.1	F530 F538	F530-A534 WeakPolarHBondContact O-CB 3.32Å; F530-A534 PolarHBondContact O-N 3.41Å; A534-F538 PolarHBondContact O-N 3.32Å; A534-F538 VanDerWaalsContact O-N 3.07Å
535	F	88.1	Confident	90.2	Very high	29 Å²	29	42.7 Å²	42.7	13%	0.127	23%	0.229	C	C	.	.	H	α-helix	trans	-66.8	-49.2	177.2	176.8	-107.2	0	0	0	112.7	F109 I112 A113 A319 F323 V531 S532 P533 L537 F538 V539	F109-F535 HydrophobicContact CD1-CD1 4.43Å; F109-F535 HydrophobicContact CD1-CD2 4.41Å; F109-F535 AromaticContact CD1-CE1 3.67Å; F109-F535 HydrophobicContact CD1-CE1 3.67Å; F109-F535 AromaticContact CD1-CE2 3.7Å; F109-F535 HydrophobicContact CD1-CE2 3.7Å; F109-F535 AromaticContact CD1-CZ 3.25Å; F109-F535 HydrophobicContact CD1-CZ 3.25Å; F109-F535 HydrophobicContact CD2-CZ 4.22Å; F109-F535 AromaticContact CE1-CD2 3.85Å; F109-F535 HydrophobicContact CE1-CD2 3.85Å; F109-F535 AromaticContact CE1-CE1 3.84Å; F109-F535 HydrophobicContact CE1-CE1 3.84Å; F109-F535 AromaticContact CE1-CE2 2.97Å; F109-F535 HydrophobicContact CE1-CE2 2.97Å; F109-F535 AromaticContact CE1-CZ 2.95Å; F109-F535 HydrophobicContact CE1-CZ 2.95Å; F109-F535 HydrophobicContact CE2-CE2 4.45Å; F109-F535 AromaticContact CE2-CZ 3.95Å; F109-F535 HydrophobicContact CE2-CZ 3.95Å; F109-F535 HydrophobicContact CG-CE1 4.21Å; F109-F535 AromaticContact CG-CZ 3.89Å; F109-F535 HydrophobicContact CG-CZ 3.89Å; F109-F535 HydrophobicContact CZ-CE1 4.41Å; F109-F535 AromaticContact CZ-CE2 3.38Å; F109-F535 HydrophobicContact CZ-CE2 3.38Å; F109-F535 AromaticContact CZ-CZ 3.26Å; F109-F535 HydrophobicContact CZ-CZ 3.26Å; I112-F535 HydrophobicContact CD1-CG 4.48Å; A113-F535 HydrophobicContact CB-CD1 3.98Å; A113-F535 HydrophobicContact CB-CE1 4.45Å; A319-F535 HydrophobicContact CB-CE1 3.9Å; A319-F535 HydrophobicContact CB-CZ 3.58Å; F323-F535 HydrophobicContact CE2-CE1 4.4Å; V531-F535 WeakPolarHBondContact O-CB 3.43Å; V531-F535 PolarHBondContact O-N 3.16Å; S532-F535 PolarHBondContact O-N 2.99Å; P533-F535 VanDerWaalsContact C-N 3.28Å; P533-F535 PolarHBondContact O-N 3.22Å; F535-L537 VanDerWaalsContact C-N 3.28Å; F535-L537 PolarHBondContact O-N 3.48Å; F535-F538 WeakPolarHBondContact O-CB 3.37Å; F535-F538 PolarHBondContact O-N 3.36Å; F535-F538 VanDerWaalsContact O-N 3.12Å; F535-V539 HydrophobicContact CD1-CG2 4.4Å; F535-V539 HydrophobicContact CD2-CG2 4.29Å; F535-V539 HydrophobicContact CE1-CG2 3.79Å; F535-V539 HydrophobicContact CE2-CG2 3.62Å; F535-V539 HydrophobicContact CZ-CG2 3.34Å; F535-V539 WeakPolarHBondContact O-CG2 3.47Å; F535-V539 PolarHBondContact O-N 2.99Å
536	L	90.3	Very high	89.4	Confident	0 Å²	0	45 Å²	45	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-59	-41.2	176.6	-81.5	173.2	0	0	0	111.8	L117 F323 L489 V492 L493 S532 P533 F538 V539 V540	L117-L536 HydrophobicContact CD1-CD1 3.68Å; F323-L536 HydrophobicContact CD2-CD2 4.21Å; F323-L536 HydrophobicContact CE1-CD2 4.09Å; F323-L536 HydrophobicContact CE2-CD2 3.43Å; F323-L536 VanDerWaalsContact CE2-CD2 3.43Å; F323-L536 HydrophobicContact CE2-CG 4.38Å; F323-L536 HydrophobicContact CZ-CD1 4.31Å; F323-L536 HydrophobicContact CZ-CD2 3.36Å; F323-L536 HydrophobicContact CZ-CG 3.98Å; L489-L536 HydrophobicContact CD2-CD2 3.98Å; V492-L536 HydrophobicContact CB-CD1 4.19Å; V492-L536 HydrophobicContact CG1-CD1 3.68Å; L493-L536 HydrophobicContact CB-CB 4.14Å; L493-L536 HydrophobicContact CB-CD1 4.44Å; L493-L536 HydrophobicContact CD1-CB 3.95Å; S532-L536 WeakPolarHBondContact O-CB 3.49Å; S532-L536 WeakPolarHBondContact O-CG 3.34Å; S532-L536 PolarHBondContact O-N 3.33Å; P533-L536 PolarHBondContact O-N 3.24Å; L536-F538 VanDerWaalsContact C-N 3.34Å; L536-F538 PolarHBondContact O-N 3.44Å; L536-V539 PolarHBondContact O-N 3.48Å; L536-V540 WeakPolarHBondContact O-CB 3.19Å; L536-V540 VanDerWaalsContact O-CG2 3.25Å; L536-V540 WeakPolarHBondContact O-CG2 3.49Å; L536-V540 PolarHBondContact O-N 3.06Å
537	L	91.9	Very high	88.2	Confident	87 Å²	87	44.4 Å²	44.4	46%	0.455	25%	0.25	S	C	.	.	H	α-helix	trans	-59.2	-46	174.8	-179.8	65	0	0	0	111.3	L493 P533 F535 V540 I541	L493-L537 HydrophobicContact CD1-CB 4.21Å; L493-L537 HydrophobicContact CD2-CB 4.23Å; L493-L537 HydrophobicContact CD2-CD1 4Å; P533-L537 VanDerWaalsContact O-CB 3.26Å; P533-L537 WeakPolarHBondContact O-CB 3.49Å; P533-L537 PolarHBondContact O-N 2.95Å; F535-L537 VanDerWaalsContact C-N 3.28Å; F535-L537 PolarHBondContact O-N 3.48Å; L537-V540 PolarHBondContact O-N 2.72Å; L537-I541 HydrophobicContact CD1-CD1 3.9Å; L537-I541 HydrophobicContact CD1-CG1 4.36Å; L537-I541 HydrophobicContact CG-CD1 3.89Å; L537-I541 VanDerWaalsContact O-CG1 3.26Å; L537-I541 WeakPolarHBondContact O-CG1 3.35Å; L537-I541 PolarHBondContact O-N 3.03Å
538	F	88.9	Confident	87.1	Confident	107 Å²	107	47 Å²	47	47%	0.469	28%	0.278	S	S	.	.	H	α-helix	trans	-59.1	-47.4	175.8	173.8	-99.7	0	0	0	112	L312 A534 F535 L536 I541 A542	L312-F538 HydrophobicContact CD1-CE1 3.9Å; L312-F538 HydrophobicContact CD1-CZ 3.68Å; A534-F538 PolarHBondContact O-N 3.32Å; A534-F538 VanDerWaalsContact O-N 3.07Å; F535-F538 WeakPolarHBondContact O-CB 3.37Å; F535-F538 PolarHBondContact O-N 3.36Å; F535-F538 VanDerWaalsContact O-N 3.12Å; L536-F538 VanDerWaalsContact C-N 3.34Å; L536-F538 PolarHBondContact O-N 3.44Å; F538-I541 PolarHBondContact O-N 3.27Å; F538-A542 VanDerWaalsContact O-CB 3.29Å; F538-A542 WeakPolarHBondContact O-CB 3.39Å; F538-A542 PolarHBondContact O-N 2.86Å
539	V	85.3	Confident	86.2	Confident	2 Å²	2	49.7 Å²	49.7	1%	0.012	31%	0.305	C	S	.	.	H	α-helix	trans	-66.6	-39.7	-179.6	-179.5	0	0	0	0	111.7	A319 L489 F535 L536 A542 S543	A319-V539 HydrophobicContact CB-CG1 4.21Å; A319-V539 HydrophobicContact CB-CG2 3.95Å; L489-V539 HydrophobicContact CD1-CG1 3.78Å; F535-V539 HydrophobicContact CD1-CG2 4.4Å; F535-V539 HydrophobicContact CD2-CG2 4.29Å; F535-V539 HydrophobicContact CE1-CG2 3.79Å; F535-V539 HydrophobicContact CE2-CG2 3.62Å; F535-V539 HydrophobicContact CZ-CG2 3.34Å; F535-V539 WeakPolarHBondContact O-CG2 3.47Å; F535-V539 PolarHBondContact O-N 2.99Å; L536-V539 PolarHBondContact O-N 3.48Å; V539-A542 PolarHBondContact O-N 3.04Å; V539-S543 WeakPolarHBondContact O-CB 3.44Å; V539-S543 PolarHBondContact O-N 3.48Å
540	V	87.8	Confident	85.7	Confident	15 Å²	15	50.2 Å²	50.2	9%	0.091	31%	0.308	C	S	.	.	H	α-helix	trans	-62.8	-44.2	176.3	169.8	0	0	0	0	110.9	T486 L489 L536 L537 T544	T486-V540 HydrophobicContact CG2-CG1 4.48Å; L489-V540 HydrophobicContact CB-CG2 3.59Å; L536-V540 WeakPolarHBondContact O-CB 3.19Å; L536-V540 VanDerWaalsContact O-CG2 3.25Å; L536-V540 WeakPolarHBondContact O-CG2 3.49Å; L536-V540 PolarHBondContact O-N 3.06Å; L537-V540 PolarHBondContact O-N 2.72Å; V540-T544 VanDerWaalsContact O-CG2 3.29Å; V540-T544 WeakPolarHBondContact O-CG2 2.98Å; V540-T544 PolarHBondContact O-N 3.12Å; V540-T544 PolarHBondContact O-OG1 2.88Å
541	I	89.2	Confident	85.2	Confident	83 Å²	83	52.8 Å²	52.8	43%	0.426	32%	0.32	S	S	.	.	H	α-helix	trans	-65	-47.6	176.6	-66.9	167.9	0	0	0	110.2	L537 F538 S543 T544 L545	L537-I541 HydrophobicContact CD1-CD1 3.9Å; L537-I541 HydrophobicContact CD1-CG1 4.36Å; L537-I541 HydrophobicContact CG-CD1 3.89Å; L537-I541 VanDerWaalsContact O-CG1 3.26Å; L537-I541 WeakPolarHBondContact O-CG1 3.35Å; L537-I541 PolarHBondContact O-N 3.03Å; F538-I541 PolarHBondContact O-N 3.27Å; I541-S543 PolarHBondContact O-N 2.84Å; I541-T544 PolarHBondContact O-N 3.33Å; I541-T544 PolarHBondContact O-OG1 2.94Å; I541-L545 HydrophobicContact CG2-CD1 3.76Å; I541-L545 HydrophobicContact CG2-CG 4.36Å; I541-L545 WeakPolarHBondContact O-CB 3.39Å; I541-L545 VanDerWaalsContact O-CG 3.28Å; I541-L545 WeakPolarHBondContact O-CG 3.43Å; I541-L545 PolarHBondContact O-N 3.11Å
542	A	84.7	Confident	84.6	Confident	8 Å²	8	52 Å²	52	7%	0.066	31%	0.31	C	S	.	.	H	α-helix	trans	-62.6	-42.7	179.8	0	0	0	0	0	111.9	L312 I316 F538 V539 L545 T546	L312-A542 HydrophobicContact CD2-CB 4.49Å; I316-A542 HydrophobicContact CD1-CB 3.82Å; I316-A542 HydrophobicContact CG1-CB 4.36Å; F538-A542 VanDerWaalsContact O-CB 3.29Å; F538-A542 WeakPolarHBondContact O-CB 3.39Å; F538-A542 PolarHBondContact O-N 2.86Å; V539-A542 PolarHBondContact O-N 3.04Å; A542-L545 PolarHBondContact O-N 3.09Å; A542-T546 VanDerWaalsContact O-CB 3.32Å; A542-T546 WeakPolarHBondContact O-CB 3.36Å; A542-T546 PolarHBondContact O-N 2.89Å; A542-T546 PolarHBondContact O-OG1 3.45Å
543	S	80.8	Confident	83.9	Confident	24 Å²	24	56.4 Å²	56.4	17%	0.168	33%	0.334	C	S	.	.	H	α-helix	trans	-61.4	-46.5	177.2	-178.3	0	0	0	0	111.4	T486 V539 I541 L545 T546 S547	T486-S543 PolarHBondContact OG1-OG 3.3Å; V539-S543 WeakPolarHBondContact O-CB 3.44Å; V539-S543 PolarHBondContact O-N 3.48Å; I541-S543 PolarHBondContact O-N 2.84Å; S543-L545 PolarHBondContact O-N 3.27Å; S543-T546 PolarHBondContact O-N 2.94Å; S543-S547 PolarHBondContact O-N 2.99Å; S543-S547 VanDerWaalsContact O-N 3.16Å; S543-S547 PolarHBondContact O-OG 3.11Å
544	T	82.3	Confident	83.1	Confident	58 Å²	58	62 Å²	62	36%	0.356	36%	0.363	S	S	.	.	H	α-helix	trans	-65.3	-38.7	179.3	52	0	0	0	0	112.3	T486 V540 I541 W566	T486-T544 HydrophobicContact CG2-CG2 3.82Å; V540-T544 VanDerWaalsContact O-CG2 3.29Å; V540-T544 WeakPolarHBondContact O-CG2 2.98Å; V540-T544 PolarHBondContact O-N 3.12Å; V540-T544 PolarHBondContact O-OG1 2.88Å; I541-T544 PolarHBondContact O-N 3.33Å; I541-T544 PolarHBondContact O-OG1 2.94Å; T544-W566 HydrophobicContact CG2-CH2 4.06Å
545	L	84.1	Confident	82.7	Confident	141 Å²	141	61.1 Å²	61.1	74%	0.738	35%	0.347	S	S	*	.	H	α-helix	trans	-72.6	-32.3	177.7	-67.4	175.3	0	0	0	113.7	I541 A542 S543	I541-L545 HydrophobicContact CG2-CD1 3.76Å; I541-L545 HydrophobicContact CG2-CG 4.36Å; I541-L545 WeakPolarHBondContact O-CB 3.39Å; I541-L545 VanDerWaalsContact O-CG 3.28Å; I541-L545 WeakPolarHBondContact O-CG 3.43Å; I541-L545 PolarHBondContact O-N 3.11Å; A542-L545 PolarHBondContact O-N 3.09Å; S543-L545 PolarHBondContact O-N 3.27Å
546	T	76.4	Confident	82.7	Confident	97 Å²	97	64 Å²	64	60%	0.595	37%	0.367	S	S	*	.	T	Hydrogen-bonded Turn	trans	-96.2	8.5	-175.9	-33.7	0	0	0	0	112.4	A542 S543 G548	A542-T546 VanDerWaalsContact O-CB 3.32Å; A542-T546 WeakPolarHBondContact O-CB 3.36Å; A542-T546 PolarHBondContact O-N 2.89Å; A542-T546 PolarHBondContact O-OG1 3.45Å; S543-T546 PolarHBondContact O-N 2.94Å; T546-G548 PolarHBondContact O-N 3.36Å
547	S	69.9	Low	82.7	Confident	51 Å²	51	64.6 Å²	64.6	36%	0.357	37%	0.37	S	S	.	.			trans	-68.5	92.2	180	-69.9	0	0	0	0	111.5	S543 W566	S543-S547 PolarHBondContact O-N 2.99Å; S543-S547 VanDerWaalsContact O-N 3.16Å; S543-S547 PolarHBondContact O-OG 3.11Å; S547-W566 WeakPolarHBondContact OG-CZ2 3.35Å
548	G	71.8	Confident	82.7	Confident	60 Å²	60	61.8 Å²	61.8	62%	0.619	36%	0.356	S	S	*	.	P	Polyproline II helix	trans	-71.7	169.9	170.2	0	0	0	0	0	113.2	T546	T546-G548 PolarHBondContact O-N 3.36Å
549	G	76.4	Confident	82.8	Confident	57 Å²	57	65.2 Å²	65.2	59%	0.588	37%	0.368	S	S	*	.	P	Polyproline II helix	trans	-65.9	139.3	174.9	0	0	0	0	0	112.3
550	L	84.1	Confident	83.2	Confident	17 Å²	17	70.8 Å²	70.8	9%	0.089	39%	0.388	C	S	.	.	P	Polyproline II helix	trans	-64.1	136.3	179.9	-171.1	66.4	0	0	0	111.4	T477 L478 K481 Y482 F557 N562	T477-L550 HydrophobicContact CG2-CD1 4.22Å; L478-L550 HydrophobicContact CB-CD2 4.15Å; L478-L550 HydrophobicContact CD1-CD2 3.98Å; K481-L550 HydrophobicContact CB-CD1 3.95Å; K481-L550 HydrophobicContact CG-CD1 3.96Å; Y482-L550 HydrophobicContact CE2-CB 4.41Å; Y482-L550 HydrophobicContact CE2-CD2 4.26Å; L550-F557 HydrophobicContact CB-CB 4.07Å; L550-F557 HydrophobicContact CB-CD2 3.89Å; L550-F557 HydrophobicContact CB-CG 4.01Å; L550-F557 HydrophobicContact CD2-CD1 3.8Å; L550-F557 HydrophobicContact CD2-CD2 3.77Å; L550-F557 HydrophobicContact CD2-CE1 3.75Å; L550-F557 HydrophobicContact CD2-CE2 3.71Å; L550-F557 HydrophobicContact CD2-CG 3.79Å; L550-F557 HydrophobicContact CD2-CZ 3.7Å; L550-F557 HydrophobicContact CG-CD1 4.48Å; L550-F557 HydrophobicContact CG-CD2 3.56Å; L550-F557 HydrophobicContact CG-CE2 3.7Å; L550-F557 HydrophobicContact CG-CG 3.97Å; L550-F557 HydrophobicContact CG-CZ 4.21Å; L550-F557 WeakPolarHBondContact O-CB 3.37Å; L550-F557 WeakPolarHBondContact O-CD2 3.24Å; L550-F557 PolarHBondContact O-N 3.01Å; L550-F557 VanDerWaalsContact O-N 3.09Å; L550-N562 WeakPolarHBondContact CB-OD1 3.44Å; L550-N562 PolarHBondContact N-OD1 3.48Å
551	K	83.6	Confident	83.4	Confident	141 Å²	141	70 Å²	70	61%	0.613	38%	0.384	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-134.4	145.3	174.9	-62.7	-172.3	-179	-177.3	0	109.6	Y555 T556	K551-Y555 WeakPolarHBondContact CA-O 3.45Å; K551-T556 HydrophobicContact CD-CG2 4.26Å; K551-T556 HydrophobicContact CG-CG2 4.25Å
552	Y	82.4	Confident	83.4	Confident	40 Å²	40	67 Å²	67	16%	0.157	37%	0.369	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.6	109.2	168	-179.5	-91.9	0	0	0	106.8	L228 I473 Y474 T477 D554 Y555	L228-Y552 HydrophobicContact CD2-CE1 4.21Å; I473-Y552 HydrophobicContact CD1-CE2 4.2Å; I473-Y552 HydrophobicContact CG1-CD2 4.45Å; I473-Y552 HydrophobicContact CG1-CE1 4.19Å; I473-Y552 HydrophobicContact CG1-CE2 3.65Å; I473-Y552 WeakPolarHBondContact CG1-OH 3.4Å; I473-Y552 HydrophobicContact CG2-CE1 4.39Å; Y474-Y552 HydrophobicContact CD1-CD1 4.33Å; Y474-Y552 HydrophobicContact CD1-CG 4.49Å; Y474-Y552 AromaticContact CE1-CD1 3.9Å; Y474-Y552 HydrophobicContact CE1-CD1 3.9Å; Y474-Y552 HydrophobicContact CE1-CG 4.43Å; T477-Y552 HydrophobicContact CG2-CD2 4.12Å; T477-Y552 WeakPolarHBondContact OG1-CD2 3.49Å; Y552-D554 PolarHBondContact O-N 2.9Å; Y552-Y555 PolarHBondContact N-O 3.12Å; Y552-Y555 WeakPolarHBondContact O-CA 3.17Å; Y552-Y555 WeakPolarHBondContact O-CB 3.18Å; Y552-Y555 PolarHBondContact O-N 3.29Å
553	D	77.3	Confident	83.8	Confident	94 Å²	94	71 Å²	71	50%	0.503	39%	0.388	S	S	.	.	T	Hydrogen-bonded Turn	trans	49.9	-123	-169.4	-56.8	-56.5	0	0	0	112.5	K213 Y555	K213-D553 IonicContact NZ-OD1 2.79Å; K213-D553 IonicContact NZ-OD2 3.68Å; K213-D553 PolarHBondContact NZ-OD2 3.33Å; D553-Y555 VanDerWaalsContact C-N 3.34Å
554	D	76.9	Confident	84.3	Confident	128 Å²	128	74 Å²	74	68%	0.684	40%	0.401	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.8	-10.1	177.4	-67.6	-37.9	0	0	0	112.9	Y552 T556	Y552-D554 PolarHBondContact O-N 2.9Å; D554-T556 PolarHBondContact O-N 3.23Å
555	Y	84	Confident	84.8	Confident	45 Å²	45	71.2 Å²	71.2	18%	0.176	38%	0.384	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.1	119	178.3	180	-98.1	0	0	0	111.2	I234 Q235 Y474 K551 Y552 D553 F557 P558	I234-Y555 PolarHBondContact N-OH 3.41Å; Q235-Y555 PolarHBondContact OE1-OH 3.31Å; Y474-Y555 AromaticContact CD1-CD1 3.71Å; Y474-Y555 HydrophobicContact CD1-CD1 3.71Å; Y474-Y555 AromaticContact CD1-CE1 3.96Å; Y474-Y555 HydrophobicContact CD1-CE1 3.96Å; Y474-Y555 HydrophobicContact CD1-CG 4.39Å; Y474-Y555 AromaticContact CE1-CD1 3.46Å; Y474-Y555 HydrophobicContact CE1-CD1 3.46Å; Y474-Y555 VanDerWaalsContact CE1-CD1 3.46Å; Y474-Y555 HydrophobicContact CE1-CD2 4.43Å; Y474-Y555 HydrophobicContact CE1-CE1 4.04Å; Y474-Y555 AromaticContact CE1-CG 3.68Å; Y474-Y555 HydrophobicContact CE1-CG 3.68Å; K551-Y555 WeakPolarHBondContact CA-O 3.45Å; Y552-Y555 PolarHBondContact N-O 3.12Å; Y552-Y555 WeakPolarHBondContact O-CA 3.17Å; Y552-Y555 WeakPolarHBondContact O-CB 3.18Å; Y552-Y555 PolarHBondContact O-N 3.29Å; D553-Y555 VanDerWaalsContact C-N 3.34Å; Y555-F557 AromaticContact CD1-CD2 3.93Å; Y555-F557 HydrophobicContact CD1-CD2 3.93Å; Y555-F557 AromaticContact CD1-CE2 4Å; Y555-F557 HydrophobicContact CD1-CE2 4Å; Y555-F557 HydrophobicContact CD1-CG 4.37Å; Y555-F557 HydrophobicContact CD1-CZ 4.49Å; Y555-F557 HydrophobicContact CE1-CD1 4.11Å; Y555-F557 AromaticContact CE1-CD2 3.96Å; Y555-F557 HydrophobicContact CE1-CD2 3.96Å; Y555-F557 HydrophobicContact CE1-CE1 4.34Å; Y555-F557 HydrophobicContact CE1-CE2 4.2Å; Y555-F557 AromaticContact CE1-CG 3.93Å; Y555-F557 HydrophobicContact CE1-CG 3.93Å; Y555-F557 HydrophobicContact CE1-CZ 4.39Å; Y555-P558 WeakPolarHBondContact OH-CD 3.39Å
556	T	88.9	Confident	85.1	Confident	89 Å²	89	68.2 Å²	68.2	55%	0.546	36%	0.364	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.2	124.8	171.7	57.4	0	0	0	0	110.3	K551 D554	K551-T556 HydrophobicContact CD-CG2 4.26Å; K551-T556 HydrophobicContact CG-CG2 4.25Å; D554-T556 PolarHBondContact O-N 3.23Å
557	F	90.6	Very high	86	Confident	13 Å²	13	65.5 Å²	65.5	6%	0.057	35%	0.354	C	S	.	.	P	Polyproline II helix	trans	-66.9	141	179.9	-78.3	-107.2	0	0	0	111.2	I234 Y474 T477 L478 L550 Y555 A561	I234-F557 HydrophobicContact CB-CE1 4.44Å; I234-F557 HydrophobicContact CD1-CD1 4.33Å; I234-F557 HydrophobicContact CD1-CE1 4.03Å; I234-F557 HydrophobicContact CG2-CD1 4.44Å; Y474-F557 HydrophobicContact CD1-CE2 4.38Å; Y474-F557 AromaticContact CD1-CZ 3.92Å; Y474-F557 HydrophobicContact CD1-CZ 3.92Å; Y474-F557 HydrophobicContact CG-CZ 4.43Å; Y474-F557 WeakPolarHBondContact O-CE1 3.45Å; Y474-F557 WeakPolarHBondContact O-CZ 3.35Å; T477-F557 HydrophobicContact CG2-CE2 4.5Å; T477-F557 HydrophobicContact CG2-CZ 4.41Å; L478-F557 HydrophobicContact CD1-CD1 4.45Å; L550-F557 HydrophobicContact CB-CB 4.07Å; L550-F557 HydrophobicContact CB-CD2 3.89Å; L550-F557 HydrophobicContact CB-CG 4.01Å; L550-F557 HydrophobicContact CD2-CD1 3.8Å; L550-F557 HydrophobicContact CD2-CD2 3.77Å; L550-F557 HydrophobicContact CD2-CE1 3.75Å; L550-F557 HydrophobicContact CD2-CE2 3.71Å; L550-F557 HydrophobicContact CD2-CG 3.79Å; L550-F557 HydrophobicContact CD2-CZ 3.7Å; L550-F557 HydrophobicContact CG-CD1 4.48Å; L550-F557 HydrophobicContact CG-CD2 3.56Å; L550-F557 HydrophobicContact CG-CE2 3.7Å; L550-F557 HydrophobicContact CG-CG 3.97Å; L550-F557 HydrophobicContact CG-CZ 4.21Å; L550-F557 WeakPolarHBondContact O-CB 3.37Å; L550-F557 WeakPolarHBondContact O-CD2 3.24Å; L550-F557 PolarHBondContact O-N 3.01Å; L550-F557 VanDerWaalsContact O-N 3.09Å; Y555-F557 AromaticContact CD1-CD2 3.93Å; Y555-F557 HydrophobicContact CD1-CD2 3.93Å; Y555-F557 AromaticContact CD1-CE2 4Å; Y555-F557 HydrophobicContact CD1-CE2 4Å; Y555-F557 HydrophobicContact CD1-CG 4.37Å; Y555-F557 HydrophobicContact CD1-CZ 4.49Å; Y555-F557 HydrophobicContact CE1-CD1 4.11Å; Y555-F557 AromaticContact CE1-CD2 3.96Å; Y555-F557 HydrophobicContact CE1-CD2 3.96Å; Y555-F557 HydrophobicContact CE1-CE1 4.34Å; Y555-F557 HydrophobicContact CE1-CE2 4.2Å; Y555-F557 AromaticContact CE1-CG 3.93Å; Y555-F557 HydrophobicContact CE1-CG 3.93Å; Y555-F557 HydrophobicContact CE1-CZ 4.39Å; F557-A561 HydrophobicContact CB-CB 4.36Å; F557-A561 HydrophobicContact CD1-CB 4.05Å
558	P	91.8	Very high	87.1	Confident	27 Å²	27	64.3 Å²	64.3	18%	0.175	35%	0.345	C	S	.	.	P	Polyproline II helix	trans	-65.4	154.4	176.5	32.1	-39.2	0	0	0	110.5	I234 Y555 W560 A561 N562	I234-P558 HydrophobicContact CG2-CG 4.02Å; Y555-P558 WeakPolarHBondContact OH-CD 3.39Å; P558-W560 VanDerWaalsContact C-N 3.27Å; P558-W560 HydrophobicContact CB-CG 4.44Å; P558-W560 HydrophobicContact CG-CD2 4.28Å; P558-W560 HydrophobicContact CG-CG 4.36Å; P558-W560 HydrophobicContact CG-CZ2 3.93Å; P558-W560 PolarHBondContact O-N 3.14Å; P558-A561 HydrophobicContact CG-CB 3.76Å; P558-A561 WeakPolarHBondContact O-CB 3.11Å; P558-A561 PolarHBondContact O-N 3.19Å; P558-N562 PolarHBondContact O-N 3.1Å; P558-N562 PolarHBondContact O-ND2 3.31Å
559	Y	90.4	Very high	88	Confident	180 Å²	180	61.6 Å²	61.6	71%	0.706	32%	0.317	S	S	*	.	H	α-helix	trans	-56.5	-39.5	-177.1	-178.2	-113.1	0	0	0	113.4	A561 N562 I563	Y559-A561 VanDerWaalsContact C-N 3.25Å; Y559-A561 PolarHBondContact O-N 3.34Å; Y559-N562 PolarHBondContact O-N 3.28Å; Y559-N562 VanDerWaalsContact O-N 3.17Å; Y559-I563 HydrophobicContact CD1-CD1 3.62Å; Y559-I563 HydrophobicContact CD1-CG1 4.39Å; Y559-I563 HydrophobicContact CE1-CD1 3.26Å; Y559-I563 HydrophobicContact CE1-CG1 4.02Å; Y559-I563 HydrophobicContact CG-CD1 4.46Å; Y559-I563 PolarHBondContact O-N 3.23Å
560	W	93.1	Very high	88.8	Confident	118 Å²	118	62.3 Å²	62.3	45%	0.447	31%	0.306	S	S	.	.	H	α-helix	trans	-62.4	-31	177.4	71.4	-99.1	0	0	0	112.9	I234 Q235 P558 I563 L564	I234-W560 HydrophobicContact CG1-CH2 4.37Å; I234-W560 HydrophobicContact CG2-CH2 3.83Å; I234-W560 HydrophobicContact CG2-CZ2 3.62Å; Q235-W560 HydrophobicContact CG-CZ2 3.87Å; P558-W560 VanDerWaalsContact C-N 3.27Å; P558-W560 HydrophobicContact CB-CG 4.44Å; P558-W560 HydrophobicContact CG-CD2 4.28Å; P558-W560 HydrophobicContact CG-CG 4.36Å; P558-W560 HydrophobicContact CG-CZ2 3.93Å; P558-W560 PolarHBondContact O-N 3.14Å; W560-I563 PolarHBondContact O-N 2.85Å; W560-L564 HydrophobicContact CZ3-CD2 4.08Å; W560-L564 WeakPolarHBondContact O-CB 3.5Å; W560-L564 PolarHBondContact O-N 3.37Å
561	A	92	Very high	89.3	Confident	0 Å²	0	63.3 Å²	63.3	0%	0	31%	0.314	C	S	.	.	H	α-helix	trans	-70.7	-39.6	177	0	0	0	0	0	110.5	I234 L478 F557 P558 Y559 I563 L564 G565	I234-A561 HydrophobicContact CD1-CB 4.38Å; I234-A561 HydrophobicContact CG2-CB 4.26Å; L478-A561 HydrophobicContact CD1-CB 4.17Å; L478-A561 WeakPolarHBondContact CD1-O 3.14Å; F557-A561 HydrophobicContact CB-CB 4.36Å; F557-A561 HydrophobicContact CD1-CB 4.05Å; P558-A561 HydrophobicContact CG-CB 3.76Å; P558-A561 WeakPolarHBondContact O-CB 3.11Å; P558-A561 PolarHBondContact O-N 3.19Å; Y559-A561 VanDerWaalsContact C-N 3.25Å; Y559-A561 PolarHBondContact O-N 3.34Å; A561-I563 VanDerWaalsContact C-N 3.32Å; A561-I563 PolarHBondContact O-N 3.33Å; A561-L564 WeakPolarHBondContact O-CB 3.37Å; A561-L564 PolarHBondContact O-N 3.07Å; A561-G565 PolarHBondContact O-N 3.25Å
562	N	90.1	Very high	89.8	Confident	20 Å²	20	56.6 Å²	56.6	11%	0.107	29%	0.285	C	S	.	.	H	α-helix	trans	-62.3	-39.9	172.5	-65.6	-67.4	0	0	0	111.6	Y482 L550 P558 Y559 L564 G565 W566	Y482-N562 PolarHBondContact OH-OD1 3.4Å; L550-N562 WeakPolarHBondContact CB-OD1 3.44Å; L550-N562 PolarHBondContact N-OD1 3.48Å; P558-N562 PolarHBondContact O-N 3.1Å; P558-N562 PolarHBondContact O-ND2 3.31Å; Y559-N562 PolarHBondContact O-N 3.28Å; Y559-N562 VanDerWaalsContact O-N 3.17Å; N562-L564 VanDerWaalsContact C-N 3.35Å; N562-G565 PolarHBondContact O-N 3.37Å; N562-W566 PolarHBondContact O-N 2.91Å
563	I	92	Very high	90.3	Very high	91 Å²	91	55.8 Å²	55.8	47%	0.467	28%	0.283	S	S	.	.	H	α-helix	trans	-61.1	-44.5	173	-66.2	166	0	0	0	110.8	Y559 W560 A561 G565 W566 G567	Y559-I563 HydrophobicContact CD1-CD1 3.62Å; Y559-I563 HydrophobicContact CD1-CG1 4.39Å; Y559-I563 HydrophobicContact CE1-CD1 3.26Å; Y559-I563 HydrophobicContact CE1-CG1 4.02Å; Y559-I563 HydrophobicContact CG-CD1 4.46Å; Y559-I563 PolarHBondContact O-N 3.23Å; W560-I563 PolarHBondContact O-N 2.85Å; A561-I563 VanDerWaalsContact C-N 3.32Å; A561-I563 PolarHBondContact O-N 3.33Å; I563-G565 VanDerWaalsContact C-N 3.34Å; I563-G565 PolarHBondContact O-N 2.94Å; I563-W566 PolarHBondContact O-N 3.18Å; I563-G567 PolarHBondContact O-N 3.32Å
564	L	93.3	Very high	91.2	Very high	86 Å²	86	54.2 Å²	54.2	45%	0.45	27%	0.274	S	S	.	.	H	α-helix	trans	-60.1	-44.8	176.7	-178.5	67.5	0	0	0	111.3	L478 W560 A561 N562 G567 V568	L478-L564 HydrophobicContact CD2-CD2 4.29Å; W560-L564 HydrophobicContact CZ3-CD2 4.08Å; W560-L564 WeakPolarHBondContact O-CB 3.5Å; W560-L564 PolarHBondContact O-N 3.37Å; A561-L564 WeakPolarHBondContact O-CB 3.37Å; A561-L564 PolarHBondContact O-N 3.07Å; N562-L564 VanDerWaalsContact C-N 3.35Å; L564-G567 CarbonylContact O-C 3.48Å; L564-G567 WeakPolarHBondContact O-CA 3.36Å; L564-G567 PolarHBondContact O-N 3.37Å; L564-V568 WeakPolarHBondContact O-CG2 3.39Å; L564-V568 PolarHBondContact O-N 3.11Å
565	G	91.6	Very high	92	Very high	0 Å²	0	52.2 Å²	52.2	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-57.2	-49	175.3	0	0	0	0	0	112.1	Y482 A561 N562 I563 G567 V568 A569	Y482-G565 WeakPolarHBondContact CB-O 3.23Å; A561-G565 PolarHBondContact O-N 3.25Å; N562-G565 PolarHBondContact O-N 3.37Å; I563-G565 VanDerWaalsContact C-N 3.34Å; I563-G565 PolarHBondContact O-N 2.94Å; G565-G567 VanDerWaalsContact C-N 3.27Å; G565-G567 PolarHBondContact O-N 3.33Å; G565-V568 WeakPolarHBondContact O-CB 3.29Å; G565-V568 PolarHBondContact O-N 3Å; G565-V568 VanDerWaalsContact O-N 3.1Å; G565-A569 PolarHBondContact O-N 3.28Å
566	W	91.1	Very high	92.5	Very high	79 Å²	79	50.6 Å²	50.6	30%	0.299	25%	0.254	S	S	.	.	H	α-helix	trans	-61.7	-34.3	172.8	-82.4	111.5	0	0	0	113.1	Y482 T544 S547 N562 I563 V568 A569 M570	Y482-W566 AromaticContact CE1-CD1 3.91Å; Y482-W566 HydrophobicContact CE1-CD2 4.17Å; Y482-W566 AromaticContact CE1-CE2 3.92Å; Y482-W566 HydrophobicContact CE1-CG 4.18Å; Y482-W566 AromaticContact CE1-NE1 3.76Å; T544-W566 HydrophobicContact CG2-CH2 4.06Å; S547-W566 WeakPolarHBondContact OG-CZ2 3.35Å; N562-W566 PolarHBondContact O-N 2.91Å; I563-W566 PolarHBondContact O-N 3.18Å; W566-V568 VanDerWaalsContact C-N 3.35Å; W566-A569 HydrophobicContact CE3-CB 4.28Å; W566-A569 PolarHBondContact O-N 2.97Å; W566-M570 VanDerWaalsContact O-CB 3.3Å; W566-M570 WeakPolarHBondContact O-CB 3.32Å; W566-M570 VanDerWaalsContact O-CG 3.23Å; W566-M570 WeakPolarHBondContact O-CG 3.47Å; W566-M570 PolarHBondContact O-N 3.35Å
567	G	93.8	Very high	92.8	Very high	39 Å²	39	48.9 Å²	48.9	40%	0.402	25%	0.245	S	C	.	.	H	α-helix	trans	-59.8	-42.3	171.4	0	0	0	0	0	112.7	I563 L564 G565 S571	I563-G567 PolarHBondContact O-N 3.32Å; L564-G567 CarbonylContact O-C 3.48Å; L564-G567 WeakPolarHBondContact O-CA 3.36Å; L564-G567 PolarHBondContact O-N 3.37Å; G565-G567 VanDerWaalsContact C-N 3.27Å; G565-G567 PolarHBondContact O-N 3.33Å; G567-S571 WeakPolarHBondContact O-CB 3.44Å; G567-S571 PolarHBondContact O-N 2.9Å
568	V	93.4	Very high	93	Very high	27 Å²	27	54.6 Å²	54.6	16%	0.164	27%	0.27	C	S	.	.	H	α-helix	trans	-68	-39.5	175	177.6	0	0	0	0	111.7	Y155 L479 A483 L564 G565 W566 S571	Y155-V568 HydrophobicContact CD2-CG1 3.82Å; Y155-V568 HydrophobicContact CE2-CG1 3.74Å; Y155-V568 HydrophobicContact CG-CG1 4.48Å; L479-V568 HydrophobicContact CD2-CG1 4.35Å; A483-V568 HydrophobicContact CB-CG1 4.11Å; L564-V568 WeakPolarHBondContact O-CG2 3.39Å; L564-V568 PolarHBondContact O-N 3.11Å; G565-V568 WeakPolarHBondContact O-CB 3.29Å; G565-V568 PolarHBondContact O-N 3Å; G565-V568 VanDerWaalsContact O-N 3.1Å; W566-V568 VanDerWaalsContact C-N 3.35Å; V568-S571 PolarHBondContact O-OG 3.3Å
569	A	91.9	Very high	93.1	Very high	2 Å²	2	55.2 Å²	55.2	2%	0.017	27%	0.269	C	S	.	.	H	α-helix	trans	-62.9	-49.8	174.4	0	0	0	0	0	110.7	Y482 G565 W566 S571 S572 M573	Y482-A569 WeakPolarHBondContact O-CB 3.3Å; G565-A569 PolarHBondContact O-N 3.28Å; W566-A569 HydrophobicContact CE3-CB 4.28Å; W566-A569 PolarHBondContact O-N 2.97Å; A569-S571 PolarHBondContact O-N 3.09Å; A569-S572 PolarHBondContact O-N 3.03Å; A569-S572 PolarHBondContact O-OG 2.97Å; A569-M573 WeakPolarHBondContact O-CG 3.14Å; A569-M573 PolarHBondContact O-N 3.15Å
570	M	92.7	Very high	93.2	Very high	73 Å²	73	47.8 Å²	47.8	36%	0.36	24%	0.244	S	C	.	.	H	α-helix	trans	-67.9	-31.7	-177.9	-70.6	-59.8	-66.4	0	0	113.1	W566 S572 M573 L574	W566-M570 VanDerWaalsContact O-CB 3.3Å; W566-M570 WeakPolarHBondContact O-CB 3.32Å; W566-M570 VanDerWaalsContact O-CG 3.23Å; W566-M570 WeakPolarHBondContact O-CG 3.47Å; W566-M570 PolarHBondContact O-N 3.35Å; M570-S572 PolarHBondContact O-N 3.07Å; M570-M573 PolarHBondContact O-N 2.57Å; M570-M573 HydrophobicContact SD-CE 4.2Å; M570-M573 HydrophobicContact SD-SD 4.08Å; M570-L574 HydrophobicContact CB-CD1 4.3Å; M570-L574 HydrophobicContact CE-CD1 4.49Å; M570-L574 HydrophobicContact CE-CD2 3.96Å; M570-L574 HydrophobicContact CE-CG 4.05Å; M570-L574 VanDerWaalsContact O-CB 3.27Å; M570-L574 WeakPolarHBondContact O-CB 3.38Å; M570-L574 WeakPolarHBondContact O-CG 3.14Å; M570-L574 PolarHBondContact O-N 3.18Å
571	S	94.8	Very high	93.3	Very high	38 Å²	38	46.4 Å²	46.4	27%	0.266	25%	0.245	S	C	.	.	H	α-helix	trans	-58.4	-36.9	178.9	65.2	0	0	0	0	112	Y155 G567 V568 A569 F575	Y155-S571 WeakPolarHBondContact CE2-OG 3.37Å; Y155-S571 PolarHBondContact OH-OG 3.17Å; G567-S571 WeakPolarHBondContact O-CB 3.44Å; G567-S571 PolarHBondContact O-N 2.9Å; V568-S571 PolarHBondContact O-OG 3.3Å; A569-S571 PolarHBondContact O-N 3.09Å; S571-F575 WeakPolarHBondContact O-CD2 3.46Å; S571-F575 WeakPolarHBondContact O-CE2 3.48Å
572	S	93.8	Very high	93.4	Very high	0 Å²	0	53.3 Å²	53.3	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-76.8	-44.6	174.6	69.5	0	0	0	0	112.3	T148 A487 A569 M570 L574 F575	T148-S572 WeakPolarHBondContact CB-O 3.25Å; T148-S572 VanDerWaalsContact CG2-O 3.3Å; T148-S572 WeakPolarHBondContact CG2-O 3.35Å; T148-S572 PolarHBondContact OG1-O 2.83Å; A487-S572 WeakPolarHBondContact CB-OG 3.41Å; A569-S572 PolarHBondContact O-N 3.03Å; A569-S572 PolarHBondContact O-OG 2.97Å; M570-S572 PolarHBondContact O-N 3.07Å; S572-L574 VanDerWaalsContact C-N 3.34Å; S572-L574 PolarHBondContact O-N 3.45Å; S572-F575 PolarHBondContact O-N 2.9Å
573	M	93.5	Very high	93.4	Very high	23 Å²	23	54.5 Å²	54.5	11%	0.113	28%	0.276	C	S	.	.	H	α-helix	trans	-65.2	-35.2	-176.8	-65.7	170.7	60.1	0	0	112.7	A487 F490 A569 M570 F575 V576 P577	A487-M573 HydrophobicContact CB-CG 4.24Å; F490-M573 HydrophobicContact CB-CE 3.95Å; F490-M573 HydrophobicContact CB-CG 4.31Å; F490-M573 HydrophobicContact CB-SD 4.43Å; F490-M573 HydrophobicContact CD1-CB 3.83Å; F490-M573 HydrophobicContact CD1-CE 4.03Å; F490-M573 HydrophobicContact CD1-CG 3.63Å; F490-M573 HydrophobicContact CD2-CE 3.81Å; F490-M573 HydrophobicContact CE1-CB 3.86Å; F490-M573 HydrophobicContact CE1-CE 4.49Å; F490-M573 HydrophobicContact CE1-CG 4.2Å; F490-M573 HydrophobicContact CE2-CE 4.31Å; F490-M573 HydrophobicContact CG-CE 3.65Å; F490-M573 HydrophobicContact CG-CG 4.1Å; F490-M573 HydrophobicContact CG-SD 4.48Å; A569-M573 WeakPolarHBondContact O-CG 3.14Å; A569-M573 PolarHBondContact O-N 3.15Å; M570-M573 PolarHBondContact O-N 2.57Å; M570-M573 HydrophobicContact SD-CE 4.2Å; M570-M573 HydrophobicContact SD-SD 4.08Å; M573-F575 PolarHBondContact O-N 2.58Å; M573-V576 PolarHBondContact O-N 3.37Å; M573-P577 VanDerWaalsContact O-CD 3.32Å; M573-P577 WeakPolarHBondContact O-CD 3.48Å
574	L	94.7	Very high	93.4	Very high	60 Å²	60	53 Å²	53	31%	0.314	27%	0.266	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.4	-16.7	-177.4	-73.3	172.2	0	0	0	113.8	M570 S572 V576 P577 F578	M570-L574 HydrophobicContact CB-CD1 4.3Å; M570-L574 HydrophobicContact CE-CD1 4.49Å; M570-L574 HydrophobicContact CE-CD2 3.96Å; M570-L574 HydrophobicContact CE-CG 4.05Å; M570-L574 VanDerWaalsContact O-CB 3.27Å; M570-L574 WeakPolarHBondContact O-CB 3.38Å; M570-L574 WeakPolarHBondContact O-CG 3.14Å; M570-L574 PolarHBondContact O-N 3.18Å; S572-L574 VanDerWaalsContact C-N 3.34Å; S572-L574 PolarHBondContact O-N 3.45Å; L574-V576 PolarHBondContact O-N 3.15Å; L574-P577 HydrophobicContact CD2-CG 4.26Å; L574-P577 WeakPolarHBondContact O-CD 3.49Å; L574-P577 WeakPolarHBondContact O-CG 3.42Å; L574-F578 HydrophobicContact CB-CD2 3.67Å; L574-F578 HydrophobicContact CB-CE2 3.51Å; L574-F578 HydrophobicContact CB-CZ 4.47Å; L574-F578 HydrophobicContact CD1-CE2 3.98Å; L574-F578 HydrophobicContact CD1-CZ 4.43Å; L574-F578 HydrophobicContact CD2-CE2 4.39Å; L574-F578 HydrophobicContact CG-CE2 4.17Å; L574-F578 VanDerWaalsContact O-CB 3.29Å; L574-F578 WeakPolarHBondContact O-CB 3.27Å; L574-F578 WeakPolarHBondContact O-CD2 3.46Å; L574-F578 WeakPolarHBondContact O-CG 3.46Å; L574-F578 PolarHBondContact O-N 3.06Å
575	F	94.3	Very high	93.3	Very high	86 Å²	86	56 Å²	56	38%	0.377	28%	0.276	S	S	.	.	H	α-helix	trans	-59.2	-33.8	173.5	-85.6	-87.1	0	0	0	112.5	T148 V151 S571 S572 M573 Y579	T148-F575 WeakPolarHBondContact OG1-CB 3.34Å; V151-F575 HydrophobicContact CG2-CD2 4.37Å; V151-F575 HydrophobicContact CG2-CE2 3.86Å; V151-F575 HydrophobicContact CG2-CZ 4.19Å; S571-F575 WeakPolarHBondContact O-CD2 3.46Å; S571-F575 WeakPolarHBondContact O-CE2 3.48Å; S572-F575 PolarHBondContact O-N 2.9Å; M573-F575 PolarHBondContact O-N 2.58Å; F575-Y579 WeakPolarHBondContact O-CB 3.42Å; F575-Y579 PolarHBondContact O-N 2.91Å
576	V	94.4	Very high	93.2	Very high	12 Å²	12	59 Å²	59	7%	0.073	30%	0.297	C	S	.	.	H	α-helix	trans	-60.2	-62.5	176.8	177.4	0	0	0	0	111.4	V145 F490 I494 M573 L574 Y579 A580	V145-V576 HydrophobicContact CB-CG2 4.49Å; V145-V576 HydrophobicContact CG2-CG1 4.41Å; V145-V576 HydrophobicContact CG2-CG2 3.87Å; F490-V576 HydrophobicContact CE1-CB 4.31Å; F490-V576 HydrophobicContact CE1-CG2 4Å; I494-V576 HydrophobicContact CG2-CG1 3.94Å; M573-V576 PolarHBondContact O-N 3.37Å; L574-V576 PolarHBondContact O-N 3.15Å; V576-Y579 PolarHBondContact O-N 2.89Å; V576-A580 WeakPolarHBondContact O-CB 3.47Å; V576-A580 PolarHBondContact O-N 3.27Å
577	P	95	Very high	93.1	Very high	53 Å²	53	56.2 Å²	56.2	34%	0.344	29%	0.289	S	S	.	.	H	α-helix	trans	-66.1	-38.7	-179.9	25.5	-34.7	0	0	0	112.5	M573 L574 Y579 A580 I581	M573-P577 VanDerWaalsContact O-CD 3.32Å; M573-P577 WeakPolarHBondContact O-CD 3.48Å; L574-P577 HydrophobicContact CD2-CG 4.26Å; L574-P577 WeakPolarHBondContact O-CD 3.49Å; L574-P577 WeakPolarHBondContact O-CG 3.42Å; P577-Y579 PolarHBondContact O-N 2.98Å; P577-A580 PolarHBondContact O-N 3.46Å; P577-I581 WeakPolarHBondContact O-CB 3.49Å; P577-I581 VanDerWaalsContact O-CG1 3.22Å; P577-I581 WeakPolarHBondContact O-CG1 3.44Å; P577-I581 PolarHBondContact O-N 3.34Å
578	F	95	Very high	92.6	Very high	133 Å²	133	59.7 Å²	59.7	58%	0.583	30%	0.304	S	S	*	.	H	α-helix	trans	-62.5	-43.5	179.2	-74.8	-45.4	0	0	0	112.2	L574 I581 Y582	L574-F578 HydrophobicContact CB-CD2 3.67Å; L574-F578 HydrophobicContact CB-CE2 3.51Å; L574-F578 HydrophobicContact CB-CZ 4.47Å; L574-F578 HydrophobicContact CD1-CE2 3.98Å; L574-F578 HydrophobicContact CD1-CZ 4.43Å; L574-F578 HydrophobicContact CD2-CE2 4.39Å; L574-F578 HydrophobicContact CG-CE2 4.17Å; L574-F578 VanDerWaalsContact O-CB 3.29Å; L574-F578 WeakPolarHBondContact O-CB 3.27Å; L574-F578 WeakPolarHBondContact O-CD2 3.46Å; L574-F578 WeakPolarHBondContact O-CG 3.46Å; L574-F578 PolarHBondContact O-N 3.06Å; F578-I581 PolarHBondContact O-N 3.09Å; F578-Y582 VanDerWaalsContact O-CB 3.31Å; F578-Y582 WeakPolarHBondContact O-CB 3.15Å; F578-Y582 PolarHBondContact O-N 2.77Å
579	Y	94.2	Very high	92.3	Very high	40 Å²	40	60.6 Å²	60.6	16%	0.157	32%	0.319	C	S	.	.	H	α-helix	trans	-68.1	-40.2	177.5	-163.6	-83.5	0	0	0	111.8	K143 Y147 F575 V576 P577 I581 Y582 K583	K143-Y579 HydrophobicContact CB-CD1 3.72Å; K143-Y579 HydrophobicContact CB-CE1 3.35Å; K143-Y579 HydrophobicContact CB-CE2 4.47Å; K143-Y579 HydrophobicContact CB-CG 4.44Å; K143-Y579 HydrophobicContact CD-CE1 4.04Å; K143-Y579 HydrophobicContact CD-CE2 4.18Å; K143-Y579 WeakPolarHBondContact CD-OH 3.42Å; K143-Y579 HydrophobicContact CG-CE1 4.27Å; Y147-Y579 HydrophobicContact CD2-CD2 4.25Å; Y147-Y579 HydrophobicContact CE2-CD2 4.02Å; Y147-Y579 AromaticContact CE2-CE2 3.84Å; Y147-Y579 HydrophobicContact CE2-CE2 3.84Å; F575-Y579 WeakPolarHBondContact O-CB 3.42Å; F575-Y579 PolarHBondContact O-N 2.91Å; V576-Y579 PolarHBondContact O-N 2.89Å; P577-Y579 PolarHBondContact O-N 2.98Å; Y579-I581 VanDerWaalsContact C-N 3.33Å; Y579-I581 PolarHBondContact O-N 3.23Å; Y579-Y582 HydrophobicContact CE2-CD1 4.3Å; Y579-Y582 PolarHBondContact O-N 3.14Å; Y579-K583 HydrophobicContact CD1-CB 4.39Å; Y579-K583 HydrophobicContact CE1-CB 4.16Å; Y579-K583 HydrophobicContact CE1-CD 4.45Å; Y579-K583 WeakPolarHBondContact O-CB 3.39Å; Y579-K583 PolarHBondContact O-N 3.12Å
580	A	93.5	Very high	92.2	Very high	23 Å²	23	64.3 Å²	64.3	19%	0.19	34%	0.342	C	S	.	.	H	α-helix	trans	-58.8	-45.7	176.2	0	0	0	0	0	111.5	I141 V576 P577 F584	I141-A580 HydrophobicContact CD1-CB 4.42Å; I141-A580 HydrophobicContact CG1-CB 3.72Å; V576-A580 WeakPolarHBondContact O-CB 3.47Å; V576-A580 PolarHBondContact O-N 3.27Å; P577-A580 PolarHBondContact O-N 3.46Å; A580-F584 VanDerWaalsContact O-CB 3.3Å; A580-F584 WeakPolarHBondContact O-CB 3.43Å; A580-F584 PolarHBondContact O-N 3.25Å
581	I	93.8	Very high	91.9	Very high	89 Å²	89	66.6 Å²	66.6	46%	0.456	36%	0.355	S	S	.	.	H	α-helix	trans	-63.4	-49.6	176.3	-69.5	168.2	0	0	0	110.7	P577 F578 Y579 K583 F584 F585	P577-I581 WeakPolarHBondContact O-CB 3.49Å; P577-I581 VanDerWaalsContact O-CG1 3.22Å; P577-I581 WeakPolarHBondContact O-CG1 3.44Å; P577-I581 PolarHBondContact O-N 3.34Å; F578-I581 PolarHBondContact O-N 3.09Å; Y579-I581 VanDerWaalsContact C-N 3.33Å; Y579-I581 PolarHBondContact O-N 3.23Å; I581-K583 VanDerWaalsContact C-N 3.34Å; I581-K583 PolarHBondContact O-N 3.27Å; I581-F584 PolarHBondContact O-N 3.02Å; I581-F585 HydrophobicContact CG2-CD2 3.59Å; I581-F585 HydrophobicContact CG2-CE2 3.55Å; I581-F585 WeakPolarHBondContact O-CD2 3.39Å; I581-F585 PolarHBondContact O-N 2.8Å
582	Y	94.3	Very high	91.4	Very high	146 Å²	146	71.7 Å²	71.7	57%	0.573	37%	0.372	S	S	*	.	H	α-helix	trans	-56.2	-47	178	167	-103	0	0	0	112	F578 Y579 F585 S586	F578-Y582 VanDerWaalsContact O-CB 3.31Å; F578-Y582 WeakPolarHBondContact O-CB 3.15Å; F578-Y582 PolarHBondContact O-N 2.77Å; Y579-Y582 HydrophobicContact CE2-CD1 4.3Å; Y579-Y582 PolarHBondContact O-N 3.14Å; Y582-F585 PolarHBondContact O-N 2.95Å; Y582-S586 WeakPolarHBondContact CE2-OG 3.45Å; Y582-S586 WeakPolarHBondContact O-CB 3.15Å; Y582-S586 PolarHBondContact O-N 3.2Å; Y582-S586 PolarHBondContact O-OG 3.31Å
583	K	91.4	Very high	91	Very high	44 Å²	44	76.1 Å²	76.1	19%	0.191	39%	0.393	C	S	.	.	H	α-helix	trans	-65.7	-42.8	179.9	-170	67.9	175.7	-170.4	0	111.3	Y579 I581 F585 S586 V587	Y579-K583 HydrophobicContact CD1-CB 4.39Å; Y579-K583 HydrophobicContact CE1-CB 4.16Å; Y579-K583 HydrophobicContact CE1-CD 4.45Å; Y579-K583 WeakPolarHBondContact O-CB 3.39Å; Y579-K583 PolarHBondContact O-N 3.12Å; I581-K583 VanDerWaalsContact C-N 3.34Å; I581-K583 PolarHBondContact O-N 3.27Å; K583-F585 VanDerWaalsContact C-N 3.31Å; K583-F585 PolarHBondContact O-N 3.31Å; K583-S586 PolarHBondContact O-N 2.86Å; K583-V587 WeakPolarHBondContact O-CG2 3.02Å; K583-V587 PolarHBondContact O-N 3.45Å
584	F	90.7	Very high	90.7	Very high	59 Å²	59	76.9 Å²	76.9	26%	0.259	40%	0.395	S	S	.	.	H	α-helix	trans	-60.8	-38.5	178	-174.4	-96.9	0	0	0	112.8	A580 I581 L591 K594 I595	A580-F584 VanDerWaalsContact O-CB 3.3Å; A580-F584 WeakPolarHBondContact O-CB 3.43Å; A580-F584 PolarHBondContact O-N 3.25Å; I581-F584 PolarHBondContact O-N 3.02Å; F584-L591 HydrophobicContact CZ-CG 4.27Å; F584-K594 HydrophobicContact CD2-CB 4.35Å; F584-K594 HydrophobicContact CE2-CB 4.02Å; F584-K594 HydrophobicContact CZ-CD 4.39Å; F584-I595 HydrophobicContact CE2-CG1 4.02Å
585	F	91.4	Very high	90.4	Very high	150 Å²	150	77 Å²	77	66%	0.658	40%	0.396	S	S	*	.	H	α-helix	trans	-78.5	-27.1	176.1	-74.5	-62.1	0	0	0	113.8	I581 Y582 K583	I581-F585 HydrophobicContact CG2-CD2 3.59Å; I581-F585 HydrophobicContact CG2-CE2 3.55Å; I581-F585 WeakPolarHBondContact O-CD2 3.39Å; I581-F585 PolarHBondContact O-N 2.8Å; Y582-F585 PolarHBondContact O-N 2.95Å; K583-F585 VanDerWaalsContact C-N 3.31Å; K583-F585 PolarHBondContact O-N 3.31Å
586	S	89.6	Confident	90	Very high	63 Å²	63	73 Å²	73	44%	0.441	38%	0.378	S	S	.	.	H	α-helix	trans	-76.8	-25.9	-179.3	-60.8	0	0	0	0	113.7	Y582 K583	Y582-S586 WeakPolarHBondContact CE2-OG 3.45Å; Y582-S586 WeakPolarHBondContact O-CB 3.15Å; Y582-S586 PolarHBondContact O-N 3.2Å; Y582-S586 PolarHBondContact O-OG 3.31Å; K583-S586 PolarHBondContact O-N 2.86Å
587	V	88.8	Confident	89.6	Confident	21 Å²	21	75.5 Å²	75.5	13%	0.127	39%	0.387	C	S	.	.	S	Bend	trans	-79.6	123.7	179.5	177	0	0	0	0	110.1	K583 K594 Y597	K583-V587 WeakPolarHBondContact O-CG2 3.02Å; K583-V587 PolarHBondContact O-N 3.45Å; V587-K594 HydrophobicContact CB-CG 4.47Å; V587-K594 HydrophobicContact CG1-CG 4.32Å; V587-K594 WeakPolarHBondContact O-CE 3.46Å; V587-K594 PolarHBondContact O-NZ 3.38Å; V587-Y597 HydrophobicContact CG1-CD2 4.25Å; V587-Y597 HydrophobicContact CG1-CG 4.42Å
588	P	83.6	Confident	89.3	Confident	112 Å²	112	73 Å²	73	73%	0.727	37%	0.371	S	S	*	.			trans	-75.1	153.4	174	32	-34.3	0	0	0	111.1
589	G	86.8	Confident	89	Confident	46 Å²	46	67.3 Å²	67.3	47%	0.474	35%	0.346	S	S	.	.	S	Bend	trans	123.5	-174.9	175.8	0	0	0	0	0	114.2	K594	G589-K594 WeakPolarHBondContact O-CE 3.42Å
590	T	89.4	Confident	88.7	Confident	80 Å²	80	65.5 Å²	65.5	49%	0.491	34%	0.34	S	S	.	.			trans	-70.7	162.6	176.9	62.3	0	0	0	0	111.7	K592 E593 K594	T590-K592 PolarHBondContact O-N 3.38Å; T590-E593 PolarHBondContact N-OE2 2.84Å; T590-E593 PolarHBondContact O-N 3.03Å; T590-E593 VanDerWaalsContact O-N 3.12Å; T590-E593 VanDerWaalsContact OG1-CG 3.3Å; T590-E593 WeakPolarHBondContact OG1-CG 3.49Å; T590-E593 PolarHBondContact OG1-N 3.49Å; T590-E593 PolarHBondContact OG1-OE2 3.24Å; T590-K594 VanDerWaalsContact O-CG 3.32Å; T590-K594 WeakPolarHBondContact O-CG 3.35Å; T590-K594 PolarHBondContact O-N 2.69Å
591	L	86.4	Confident	88.5	Confident	121 Å²	121	64.4 Å²	64.4	63%	0.634	33%	0.331	S	S	*	.	H	α-helix	trans	-56.7	-36.6	-179.3	-166.6	142.1	0	0	0	112.5	F584 I595	F584-L591 HydrophobicContact CZ-CG 4.27Å; L591-I595 HydrophobicContact CD2-CD1 3.65Å; L591-I595 VanDerWaalsContact O-CG1 3.3Å; L591-I595 WeakPolarHBondContact O-CG1 3.49Å; L591-I595 PolarHBondContact O-N 2.9Å; L591-I595 VanDerWaalsContact O-N 3.13Å
592	K	85.3	Confident	88.2	Confident	145 Å²	145	64 Å²	64	63%	0.63	33%	0.327	S	S	*	.	H	α-helix	trans	-69.1	-43.3	177	-171	178.8	179.8	-176.9	0	112.4	T590 I595 A596 F616	T590-K592 PolarHBondContact O-N 3.38Å; K592-I595 PolarHBondContact O-N 3.24Å; K592-A596 WeakPolarHBondContact O-CB 3.47Å; K592-A596 PolarHBondContact O-N 3.49Å; K592-F616 HydrophobicContact CG-CE2 3.91Å; K592-F616 HydrophobicContact CG-CZ 4.08Å
593	E	84.8	Confident	87.7	Confident	92 Å²	92	62.8 Å²	62.8	43%	0.43	33%	0.326	S	S	.	.	H	α-helix	trans	-66.2	-42.6	177	-70.8	162.8	158.1	0	0	111.2	T590 I595 A596 Y597	T590-E593 PolarHBondContact N-OE2 2.84Å; T590-E593 PolarHBondContact O-N 3.03Å; T590-E593 VanDerWaalsContact O-N 3.12Å; T590-E593 VanDerWaalsContact OG1-CG 3.3Å; T590-E593 WeakPolarHBondContact OG1-CG 3.49Å; T590-E593 PolarHBondContact OG1-N 3.49Å; T590-E593 PolarHBondContact OG1-OE2 3.24Å; E593-I595 VanDerWaalsContact C-N 3.34Å; E593-I595 PolarHBondContact O-N 3.38Å; E593-A596 WeakPolarHBondContact O-CB 2.99Å; E593-A596 PolarHBondContact O-N 3.37Å; E593-A596 VanDerWaalsContact O-N 3.12Å; E593-Y597 HydrophobicContact CB-CD2 4.48Å; E593-Y597 HydrophobicContact CB-CE2 4.47Å; E593-Y597 WeakPolarHBondContact O-CD2 2.74Å; E593-Y597 PolarHBondContact O-N 3.42Å
594	K	88.3	Confident	87.4	Confident	39 Å²	39	61.7 Å²	61.7	17%	0.17	32%	0.321	C	S	.	.	H	α-helix	trans	-55.5	-49.3	175.1	-72.6	-178.5	-178.9	-140.6	0	111.4	F584 V587 G589 T590 A596 C598	F584-K594 HydrophobicContact CD2-CB 4.35Å; F584-K594 HydrophobicContact CE2-CB 4.02Å; F584-K594 HydrophobicContact CZ-CD 4.39Å; V587-K594 HydrophobicContact CB-CG 4.47Å; V587-K594 HydrophobicContact CG1-CG 4.32Å; V587-K594 WeakPolarHBondContact O-CE 3.46Å; V587-K594 PolarHBondContact O-NZ 3.38Å; G589-K594 WeakPolarHBondContact O-CE 3.42Å; T590-K594 VanDerWaalsContact O-CG 3.32Å; T590-K594 WeakPolarHBondContact O-CG 3.35Å; T590-K594 PolarHBondContact O-N 2.69Å; K594-A596 VanDerWaalsContact C-N 3.34Å; K594-A596 PolarHBondContact O-N 2.97Å; K594-C598 WeakPolarHBondContact O-CB 3.06Å; K594-C598 PolarHBondContact O-N 2.66Å; K594-C598 VanDerWaalsContact O-N 3.08Å; K594-C598 PolarHBondContact O-SG 2.79Å
595	I	87.7	Confident	87.2	Confident	63 Å²	63	61.2 Å²	61.2	32%	0.323	32%	0.32	S	S	.	.	H	α-helix	trans	-59.9	-46.6	176.5	-69	172	0	0	0	110.2	F584 L591 K592 E593 Y597 C598 I599 F616	F584-I595 HydrophobicContact CE2-CG1 4.02Å; L591-I595 HydrophobicContact CD2-CD1 3.65Å; L591-I595 VanDerWaalsContact O-CG1 3.3Å; L591-I595 WeakPolarHBondContact O-CG1 3.49Å; L591-I595 PolarHBondContact O-N 2.9Å; L591-I595 VanDerWaalsContact O-N 3.13Å; K592-I595 PolarHBondContact O-N 3.24Å; E593-I595 VanDerWaalsContact C-N 3.34Å; E593-I595 PolarHBondContact O-N 3.38Å; I595-Y597 PolarHBondContact O-N 2.91Å; I595-C598 PolarHBondContact O-N 2.92Å; I595-I599 HydrophobicContact CG2-CD1 3.96Å; I595-I599 HydrophobicContact CG2-CG2 4.47Å; I595-I599 VanDerWaalsContact O-CG1 3.31Å; I595-I599 WeakPolarHBondContact O-CG1 3.27Å; I595-I599 PolarHBondContact O-N 3.04Å; I595-I599 VanDerWaalsContact O-N 3.08Å; I595-F616 HydrophobicContact CG2-CE1 4.01Å; I595-F616 HydrophobicContact CG2-CZ 4.32Å
596	A	86	Confident	86.7	Confident	2 Å²	2	59.5 Å²	59.5	2%	0.017	31%	0.314	C	S	.	.	H	α-helix	trans	-58.8	-48.3	-179	0	0	0	0	0	112.9	K592 E593 K594 C598 T600 V608 V613 F616	K592-A596 WeakPolarHBondContact O-CB 3.47Å; K592-A596 PolarHBondContact O-N 3.49Å; E593-A596 WeakPolarHBondContact O-CB 2.99Å; E593-A596 PolarHBondContact O-N 3.37Å; E593-A596 VanDerWaalsContact O-N 3.12Å; K594-A596 VanDerWaalsContact C-N 3.34Å; K594-A596 PolarHBondContact O-N 2.97Å; A596-C598 VanDerWaalsContact C-N 3.29Å; A596-C598 PolarHBondContact O-N 3.21Å; A596-T600 WeakPolarHBondContact O-CB 3.35Å; A596-T600 PolarHBondContact O-N 3.26Å; A596-T600 PolarHBondContact O-OG1 3.33Å; A596-V608 HydrophobicContact CB-CG1 3.59Å; A596-V613 HydrophobicContact CB-CG1 4.24Å; A596-V613 HydrophobicContact CB-CG2 3.73Å; A596-F616 HydrophobicContact CB-CE2 4.01Å; A596-F616 HydrophobicContact CB-CZ 3.83Å
597	Y	86.6	Confident	86.3	Confident	64 Å²	64	58.9 Å²	58.9	25%	0.251	31%	0.305	S	S	.	.	H	α-helix	trans	-67.9	-27.5	177.7	-76.5	-69.7	0	0	0	113.3	V587 E593 I595 H605 V608	V587-Y597 HydrophobicContact CG1-CD2 4.25Å; V587-Y597 HydrophobicContact CG1-CG 4.42Å; E593-Y597 HydrophobicContact CB-CD2 4.48Å; E593-Y597 HydrophobicContact CB-CE2 4.47Å; E593-Y597 WeakPolarHBondContact O-CD2 2.74Å; E593-Y597 PolarHBondContact O-N 3.42Å; I595-Y597 PolarHBondContact O-N 2.91Å; Y597-H605 HydrophobicContact CD1-CB 4.17Å; Y597-H605 AromaticContact CD1-CG 3.81Å; Y597-H605 AromaticContact CD1-ND1 3.92Å; Y597-H605 HydrophobicContact CE1-CB 4.04Å; Y597-H605 PolarHBondContact O-NE2 3.16Å; Y597-V608 HydrophobicContact CD1-CB 4.21Å; Y597-V608 HydrophobicContact CD1-CG1 4.01Å; Y597-V608 HydrophobicContact CD2-CG1 4.04Å; Y597-V608 HydrophobicContact CE1-CB 3.86Å; Y597-V608 HydrophobicContact CE1-CG1 3.81Å; Y597-V608 HydrophobicContact CE2-CG1 3.83Å; Y597-V608 HydrophobicContact CG-CG1 4.11Å
598	C	88	Confident	85.9	Confident	1 Å²	1	58.4 Å²	58.4	1%	0.007	30%	0.303	C	S	.	.	H	α-helix	trans	-77.3	-32.4	179.6	-72	0	0	0	0	113.5	P140 I141 K594 I595 A596	P140-C598 VanDerWaalsContact CD-O 3.31Å; P140-C598 WeakPolarHBondContact CD-O 3.07Å; I141-C598 HydrophobicContact CB-CB 4.14Å; I141-C598 WeakPolarHBondContact CB-O 3.46Å; I141-C598 HydrophobicContact CD1-CB 4.44Å; I141-C598 PolarHBondContact N-O 2.93Å; K594-C598 WeakPolarHBondContact O-CB 3.06Å; K594-C598 PolarHBondContact O-N 2.66Å; K594-C598 VanDerWaalsContact O-N 3.08Å; K594-C598 PolarHBondContact O-SG 2.79Å; I595-C598 PolarHBondContact O-N 2.92Å; A596-C598 VanDerWaalsContact C-N 3.29Å; A596-C598 PolarHBondContact O-N 3.21Å
599	I	88.7	Confident	85.6	Confident	13 Å²	13	56.3 Å²	56.3	7%	0.067	30%	0.295	C	S	.	.	H	α-helix	trans	-98.3	-17.4	-177.4	69.4	-171.8	0	0	0	113.7	F502 I595 Q615 F616	F502-I599 HydrophobicContact CD1-CB 4.46Å; F502-I599 HydrophobicContact CD1-CG2 4.07Å; F502-I599 HydrophobicContact CE1-CG2 4.3Å; I595-I599 HydrophobicContact CG2-CD1 3.96Å; I595-I599 HydrophobicContact CG2-CG2 4.47Å; I595-I599 VanDerWaalsContact O-CG1 3.31Å; I595-I599 WeakPolarHBondContact O-CG1 3.27Å; I595-I599 PolarHBondContact O-N 3.04Å; I595-I599 VanDerWaalsContact O-N 3.08Å; I599-Q615 HydrophobicContact CD1-CB 3.47Å; I599-Q615 VanDerWaalsContact CD1-CB 3.47Å; I599-Q615 HydrophobicContact CD1-CG 4.02Å; I599-Q615 HydrophobicContact CG1-CB 4Å; I599-Q615 HydrophobicContact CG1-CG 4.01Å; I599-Q615 PolarHBondContact O-NE2 2.87Å; I599-F616 HydrophobicContact CD1-CD1 4.47Å; I599-F616 HydrophobicContact CD1-CE1 3.98Å
600	T	87.8	Confident	85.2	Confident	3 Å²	3	59.8 Å²	59.8	2%	0.018	30%	0.302	C	S	.	.	S	Bend	trans	-88.6	138.2	-179.3	-51.6	0	0	0	0	110.1	P140 A596 E604 H605 V608	P140-T600 VanDerWaalsContact CD-O 3.25Å; P140-T600 WeakPolarHBondContact CD-O 3.3Å; A596-T600 WeakPolarHBondContact O-CB 3.35Å; A596-T600 PolarHBondContact O-N 3.26Å; A596-T600 PolarHBondContact O-OG1 3.33Å; T600-E604 HydrophobicContact CG2-CB 3.68Å; T600-H605 PolarHBondContact O-NE2 3.14Å; T600-H605 VanDerWaalsContact O-NE2 3.15Å; T600-V608 HydrophobicContact CG2-CG2 3.63Å
601	P	88.9	Confident	84.5	Confident	0 Å²	0	58.8 Å²	58.8	0%	0	31%	0.308	C	S	.	.			trans	-55.7	146.9	174.8	-21	27.4	0	0	0	112.6	K137 I138 Y503 H603 E604 H605	K137-P601 CarbonylContact O-C 3.59Å; K137-P601 VanDerWaalsContact O-CA 3.24Å; K137-P601 WeakPolarHBondContact O-CA 3.25Å; I138-P601 WeakPolarHBondContact O-CA 3.36Å; I138-P601 VanDerWaalsContact O-CG 3.27Å; I138-P601 WeakPolarHBondContact O-CG 3.25Å; Y503-P601 HydrophobicContact CD2-CG 4.06Å; Y503-P601 HydrophobicContact CE2-CG 3.85Å; P601-H603 VanDerWaalsContact C-N 3.26Å; P601-H603 WeakPolarHBondContact CB-CE1 3.34Å; P601-H603 WeakPolarHBondContact CB-ND1 3.46Å; P601-H603 PolarHBondContact O-N 3.15Å; P601-E604 PolarHBondContact O-N 3.41Å; P601-H605 PolarHBondContact O-CD2 3.24Å; P601-H605 PolarHBondContact O-N 3.16Å
602	E	87.3	Confident	84.1	Confident	80 Å²	80	58.8 Å²	58.8	37%	0.374	31%	0.309	S	S	.	.	G	3₁₀ helix	trans	-59	-35.5	-176.5	-63.7	-169.4	163.5	0	0	113.2	K137 P140 E604 H605	K137-E602 HydrophobicContact CB-CG 4.28Å; K137-E602 HydrophobicContact CG-CG 4.38Å; K137-E602 WeakPolarHBondContact CG-OE2 3.46Å; K137-E602 PolarHBondContact O-N 2.98Å; P140-E602 HydrophobicContact CG-CG 3.83Å; E602-E604 PolarHBondContact O-N 2.03Å; E602-H605 WeakPolarHBondContact O-CB 3.23Å; E602-H605 PolarHBondContact O-N 2.83Å
603	H	84.4	Confident	83.7	Confident	121 Å²	121	52.6 Å²	52.6	56%	0.56	28%	0.283	S	S	*	.	G	3₁₀ helix	trans	-67.2	-19.5	178	67.3	-87.4	0	0	0	113.3	P601 H606	P601-H603 VanDerWaalsContact C-N 3.26Å; P601-H603 WeakPolarHBondContact CB-CE1 3.34Å; P601-H603 WeakPolarHBondContact CB-ND1 3.46Å; P601-H603 PolarHBondContact O-N 3.15Å; H603-H606 PolarHBondContact O-CE1 3.27Å; H603-H606 PolarHBondContact O-ND1 2.96Å
604	E	85.3	Confident	83.3	Confident	20 Å²	20	54.3 Å²	54.3	9%	0.093	29%	0.286	C	S	.	.	G	3₁₀ helix	trans	-101.6	6.5	179.6	-73.2	-177.2	159	0	0	113.2	R507 T600 P601 E602 H606 L607 V608	R507-E604 IonicContact CZ-OE1 3.18Å; R507-E604 IonicContact CZ-OE2 2.76Å; R507-E604 IonicContact NH1-OE1 2.79Å; R507-E604 IonicContact NH1-OE2 2.92Å; R507-E604 PolarHBondContact NH1-OE2 2.84Å; R507-E604 IonicContact NH2-OE1 2.82Å; R507-E604 PolarHBondContact NH2-OE1 3.39Å; R507-E604 IonicContact NH2-OE2 2.75Å; R507-E604 PolarHBondContact NH2-OE2 2.86Å; T600-E604 HydrophobicContact CG2-CB 3.68Å; P601-E604 PolarHBondContact O-N 3.41Å; E602-E604 PolarHBondContact O-N 2.03Å; E604-H606 PolarHBondContact O-N 3.35Å; E604-H606 VanDerWaalsContact O-N 3.09Å; E604-L607 HydrophobicContact CB-CD1 4.16Å; E604-L607 HydrophobicContact CG-CD1 3.99Å; E604-L607 WeakPolarHBondContact O-CA 3.49Å; E604-L607 WeakPolarHBondContact O-CB 3.4Å; E604-L607 PolarHBondContact O-N 2.62Å; E604-V608 PolarHBondContact O-N 2.82Å
605	H	85.3	Confident	82.8	Confident	49 Å²	49	52.7 Å²	52.7	23%	0.227	28%	0.278	C	S	.	.	H	α-helix	trans	-58.8	-25.6	179	-76.3	-171.4	0	0	0	113.2	Y597 T600 P601 E602 L607 V608 A609	Y597-H605 HydrophobicContact CD1-CB 4.17Å; Y597-H605 AromaticContact CD1-CG 3.81Å; Y597-H605 AromaticContact CD1-ND1 3.92Å; Y597-H605 HydrophobicContact CE1-CB 4.04Å; Y597-H605 PolarHBondContact O-NE2 3.16Å; T600-H605 PolarHBondContact O-NE2 3.14Å; T600-H605 VanDerWaalsContact O-NE2 3.15Å; P601-H605 PolarHBondContact O-CD2 3.24Å; P601-H605 PolarHBondContact O-N 3.16Å; E602-H605 WeakPolarHBondContact O-CB 3.23Å; E602-H605 PolarHBondContact O-N 2.83Å; H605-L607 VanDerWaalsContact C-N 3.31Å; H605-L607 PolarHBondContact O-N 3.13Å; H605-V608 WeakPolarHBondContact O-CB 3.48Å; H605-V608 PolarHBondContact O-N 3.49Å; H605-A609 PolarHBondContact O-N 2.98Å; H605-A609 VanDerWaalsContact O-N 3.12Å
606	H	82.3	Confident	82.5	Confident	115 Å²	115	54 Å²	54	53%	0.532	28%	0.282	S	S	.	.	H	α-helix	trans	-64.4	-31.2	171.4	68.4	-83.4	0	0	0	113.2	H603 E604 N610	H603-H606 PolarHBondContact O-CE1 3.27Å; H603-H606 PolarHBondContact O-ND1 2.96Å; E604-H606 PolarHBondContact O-N 3.35Å; E604-H606 VanDerWaalsContact O-N 3.09Å; H606-N610 PolarHBondContact O-N 3.16Å; H606-N610 PolarHBondContact O-ND2 2.93Å
607	L	81.1	Confident	82.2	Confident	49 Å²	49	57.1 Å²	57.1	26%	0.257	30%	0.301	S	S	.	.	H	α-helix	trans	-74.3	-32.7	175.1	-59.8	177.5	0	0	0	111.8	E604 H605 A609 N610 G611 N612	E604-L607 HydrophobicContact CB-CD1 4.16Å; E604-L607 HydrophobicContact CG-CD1 3.99Å; E604-L607 WeakPolarHBondContact O-CA 3.49Å; E604-L607 WeakPolarHBondContact O-CB 3.4Å; E604-L607 PolarHBondContact O-N 2.62Å; H605-L607 VanDerWaalsContact C-N 3.31Å; H605-L607 PolarHBondContact O-N 3.13Å; L607-A609 VanDerWaalsContact C-N 3.34Å; L607-N610 CarbonylContact O-C 3.28Å; L607-N610 PolarHBondContact O-N 3.42Å; L607-N610 VanDerWaalsContact O-N 3.15Å; L607-G611 PolarHBondContact O-N 3.47Å; L607-N612 PolarHBondContact O-N 2.8Å
608	V	80.6	Confident	81.7	Confident	12 Å²	12	60.3 Å²	60.3	7%	0.073	32%	0.322	C	S	.	.	H	α-helix	trans	-63.8	-42.5	173.3	-177.4	0	0	0	0	110.5	A596 Y597 T600 E604 H605 N610 G611 V613	A596-V608 HydrophobicContact CB-CG1 3.59Å; Y597-V608 HydrophobicContact CD1-CB 4.21Å; Y597-V608 HydrophobicContact CD1-CG1 4.01Å; Y597-V608 HydrophobicContact CD2-CG1 4.04Å; Y597-V608 HydrophobicContact CE1-CB 3.86Å; Y597-V608 HydrophobicContact CE1-CG1 3.81Å; Y597-V608 HydrophobicContact CE2-CG1 3.83Å; Y597-V608 HydrophobicContact CG-CG1 4.11Å; T600-V608 HydrophobicContact CG2-CG2 3.63Å; E604-V608 PolarHBondContact O-N 2.82Å; H605-V608 WeakPolarHBondContact O-CB 3.48Å; H605-V608 PolarHBondContact O-N 3.49Å; V608-N610 PolarHBondContact O-N 3.11Å; V608-G611 PolarHBondContact O-N 2.92Å; V608-V613 HydrophobicContact CG1-CG2 4.24Å; V608-V613 HydrophobicContact CG2-CG2 4.4Å
609	A	76.8	Confident	81.2	Confident	68 Å²	68	70.3 Å²	70.3	56%	0.562	36%	0.359	S	S	*	.	H	α-helix	trans	-59.6	-30.2	173.9	0	0	0	0	0	112.5	H605 L607 G611	H605-A609 PolarHBondContact O-N 2.98Å; H605-A609 VanDerWaalsContact O-N 3.12Å; L607-A609 VanDerWaalsContact C-N 3.34Å; A609-G611 VanDerWaalsContact C-N 3.29Å; A609-G611 PolarHBondContact O-N 3.38Å
610	N	78.1	Confident	81	Confident	119 Å²	119	71.2 Å²	71.2	64%	0.636	36%	0.363	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.3	4.9	175.1	-64.2	-18.7	0	0	0	113.6	H606 L607 V608 N612	H606-N610 PolarHBondContact O-N 3.16Å; H606-N610 PolarHBondContact O-ND2 2.93Å; L607-N610 CarbonylContact O-C 3.28Å; L607-N610 PolarHBondContact O-N 3.42Å; L607-N610 VanDerWaalsContact O-N 3.15Å; V608-N610 PolarHBondContact O-N 3.11Å; N610-N612 VanDerWaalsContact C-N 3.27Å; N610-N612 PolarHBondContact O-N 3.03Å
611	G	76.1	Confident	80.7	Confident	59 Å²	59	75.2 Å²	75.2	61%	0.608	38%	0.378	S	S	*	.	T	Hydrogen-bonded Turn	trans	77.8	1.6	179.8	0	0	0	0	0	115.6	L607 V608 A609 V613	L607-G611 PolarHBondContact O-N 3.47Å; V608-G611 PolarHBondContact O-N 2.92Å; A609-G611 VanDerWaalsContact C-N 3.29Å; A609-G611 PolarHBondContact O-N 3.38Å; G611-V613 PolarHBondContact O-N 3Å
612	N	75.9	Confident	80.3	Confident	121 Å²	121	81.1 Å²	81.1	65%	0.647	41%	0.409	S	S	*	.			trans	-94.9	89	-176.8	-82.8	-26.5	0	0	0	111.4	L607 N610	L607-N612 PolarHBondContact O-N 2.8Å; N610-N612 VanDerWaalsContact C-N 3.27Å; N610-N612 PolarHBondContact O-N 3.03Å
613	V	78.5	Confident	79.9	Confident	15 Å²	15	78.3 Å²	78.3	9%	0.091	40%	0.399	C	S	.	.			trans	-107.4	109.7	179.2	-174.1	0	0	0	0	109.7	A596 V608 G611 Q615 F616	A596-V613 HydrophobicContact CB-CG1 4.24Å; A596-V613 HydrophobicContact CB-CG2 3.73Å; V608-V613 HydrophobicContact CG1-CG2 4.24Å; V608-V613 HydrophobicContact CG2-CG2 4.4Å; G611-V613 PolarHBondContact O-N 3Å; V613-Q615 VanDerWaalsContact C-N 3.29Å; V613-Q615 HydrophobicContact CG1-CB 4.27Å; V613-Q615 PolarHBondContact O-N 3.03Å; V613-F616 HydrophobicContact CB-CB 4.47Å; V613-F616 HydrophobicContact CB-CD2 3.55Å; V613-F616 HydrophobicContact CB-CE2 3.89Å; V613-F616 HydrophobicContact CB-CG 4.02Å; V613-F616 HydrophobicContact CG1-CD1 4.18Å; V613-F616 HydrophobicContact CG1-CD2 3.81Å; V613-F616 HydrophobicContact CG1-CE1 4.31Å; V613-F616 HydrophobicContact CG1-CE2 3.95Å; V613-F616 HydrophobicContact CG1-CG 3.92Å; V613-F616 HydrophobicContact CG1-CZ 4.2Å; V613-F616 HydrophobicContact CG2-CD2 4Å; V613-F616 HydrophobicContact CG2-CE2 3.9Å; V613-F616 PolarHBondContact O-N 3.09Å
614	R	75.1	Confident	79.4	Confident	128 Å²	128	75.7 Å²	75.7	48%	0.483	39%	0.389	S	S	.	.	G	3₁₀ helix	trans	-63.4	-35.5	-177.8	-70.2	-175.8	-173.3	-176.1	4	112.5	F616 T617 H620	R614-F616 PolarHBondContact O-N 3.44Å; R614-F616 VanDerWaalsContact O-N 3.15Å; R614-T617 WeakPolarHBondContact O-CB 3.45Å; R614-T617 PolarHBondContact O-N 3.49Å; R614-T617 PolarHBondContact O-OG1 2.87Å; R614-H620 WeakPolarHBondContact O-CB 3.43Å
615	Q	79.1	Confident	79.1	Confident	4 Å²	4	78.5 Å²	78.5	2%	0.019	40%	0.404	C	S	.	.	G	3₁₀ helix	trans	-65.8	-14.7	-180	-62.8	82.7	-11.4	0	0	112.9	I599 V613 T617 W621	I599-Q615 HydrophobicContact CD1-CB 3.47Å; I599-Q615 VanDerWaalsContact CD1-CB 3.47Å; I599-Q615 HydrophobicContact CD1-CG 4.02Å; I599-Q615 HydrophobicContact CG1-CB 4Å; I599-Q615 HydrophobicContact CG1-CG 4.01Å; I599-Q615 PolarHBondContact O-NE2 2.87Å; V613-Q615 VanDerWaalsContact C-N 3.29Å; V613-Q615 HydrophobicContact CG1-CB 4.27Å; V613-Q615 PolarHBondContact O-N 3.03Å; Q615-T617 VanDerWaalsContact C-N 3.32Å; Q615-W621 PolarHBondContact O-NE1 3.15Å
616	F	81.4	Confident	78.8	Confident	91 Å²	91	80.1 Å²	80.1	40%	0.399	41%	0.413	S	S	.	.	G	3₁₀ helix	trans	-85.7	-4.2	172	-64.8	-20.2	0	0	0	113.3	K592 I595 A596 I599 V613 R614	K592-F616 HydrophobicContact CG-CE2 3.91Å; K592-F616 HydrophobicContact CG-CZ 4.08Å; I595-F616 HydrophobicContact CG2-CE1 4.01Å; I595-F616 HydrophobicContact CG2-CZ 4.32Å; A596-F616 HydrophobicContact CB-CE2 4.01Å; A596-F616 HydrophobicContact CB-CZ 3.83Å; I599-F616 HydrophobicContact CD1-CD1 4.47Å; I599-F616 HydrophobicContact CD1-CE1 3.98Å; V613-F616 HydrophobicContact CB-CB 4.47Å; V613-F616 HydrophobicContact CB-CD2 3.55Å; V613-F616 HydrophobicContact CB-CE2 3.89Å; V613-F616 HydrophobicContact CB-CG 4.02Å; V613-F616 HydrophobicContact CG1-CD1 4.18Å; V613-F616 HydrophobicContact CG1-CD2 3.81Å; V613-F616 HydrophobicContact CG1-CE1 4.31Å; V613-F616 HydrophobicContact CG1-CE2 3.95Å; V613-F616 HydrophobicContact CG1-CG 3.92Å; V613-F616 HydrophobicContact CG1-CZ 4.2Å; V613-F616 HydrophobicContact CG2-CD2 4Å; V613-F616 HydrophobicContact CG2-CE2 3.9Å; V613-F616 PolarHBondContact O-N 3.09Å; R614-F616 PolarHBondContact O-N 3.44Å; R614-F616 VanDerWaalsContact O-N 3.15Å
617	T	78.4	Confident	78.6	Confident	67 Å²	67	78.1 Å²	78.1	41%	0.411	41%	0.406	S	S	.	.	S	Bend	trans	-92	136.4	178.9	69.9	0	0	0	0	111.5	R614 Q615 R619 H620	R614-T617 WeakPolarHBondContact O-CB 3.45Å; R614-T617 PolarHBondContact O-N 3.49Å; R614-T617 PolarHBondContact O-OG1 2.87Å; Q615-T617 VanDerWaalsContact C-N 3.32Å; T617-R619 PolarHBondContact O-N 3.24Å; T617-H620 WeakPolarHBondContact O-CB 3.21Å; T617-H620 PolarHBondContact O-N 3.02Å; T617-H620 VanDerWaalsContact O-N 3.11Å
618	L	76.4	Confident	78.5	Confident	132 Å²	132	79.8 Å²	79.8	69%	0.691	42%	0.415	S	S	*	.	H	α-helix	trans	-61.7	-28.1	178.3	-134.2	147.6	0	0	0	111.9	H620 W621 L622	L618-H620 VanDerWaalsContact C-N 3.34Å; L618-H620 PolarHBondContact O-N 3.25Å; L618-W621 PolarHBondContact O-N 3.32Å; L618-L622 HydrophobicContact CD2-CD1 3.37Å; L618-L622 HydrophobicContact CD2-CG 3.86Å; L618-L622 WeakPolarHBondContact O-CG 3.15Å; L618-L622 PolarHBondContact O-N 3.12Å; L618-L622 VanDerWaalsContact O-N 3.12Å
619	R	78.3	Confident	78.3	Confident	211 Å²	211	84.1 Å²	84.1	80%	0.796	44%	0.436	S	S	*	.	H	α-helix	trans	-61.1	-38.4	175.2	-170.8	176	178.7	-179	-0.3	112.6	T617 L622 A623	T617-R619 PolarHBondContact O-N 3.24Å; R619-L622 PolarHBondContact O-N 3.22Å; R619-A623 VanDerWaalsContact O-CB 3.32Å; R619-A623 WeakPolarHBondContact O-CB 3.09Å; R619-A623 PolarHBondContact O-N 2.79Å
620	H	83.3	Confident	78.4	Confident	31 Å²	31	85.1 Å²	85.1	14%	0.144	43%	0.428	C	S	.	.	H	α-helix	trans	-60.2	-46.6	177.4	177.8	84.2	0	0	0	111.7	W501 F502 R614 T617 L618	W501-H620 PolarHBondContact O-NE2 3.1Å; F502-H620 PolarHBondContact O-CE1 2.72Å; F502-H620 PolarHBondContact O-NE2 3.08Å; R614-H620 WeakPolarHBondContact O-CB 3.43Å; T617-H620 WeakPolarHBondContact O-CB 3.21Å; T617-H620 PolarHBondContact O-N 3.02Å; T617-H620 VanDerWaalsContact O-N 3.11Å; L618-H620 VanDerWaalsContact C-N 3.34Å; L618-H620 PolarHBondContact O-N 3.25Å
621	W	83.3	Confident	78.4	Confident	87 Å²	87	82.7 Å²	82.7	33%	0.33	41%	0.413	S	S	.	.	H	α-helix	trans	-74.4	-28.9	-177.2	-61.7	95.5	0	0	0	113.2	W501 F502 K529 Q615 L618	W501-W621 HydrophobicContact CB-CZ3 4.09Å; W501-W621 AromaticContact CE3-CE3 3.81Å; W501-W621 HydrophobicContact CE3-CE3 3.81Å; W501-W621 HydrophobicContact CE3-CZ3 4.21Å; W501-W621 HydrophobicContact CZ3-CE3 4.43Å; F502-W621 HydrophobicContact CD1-CH2 4.2Å; F502-W621 HydrophobicContact CE1-CH2 4.21Å; F502-W621 HydrophobicContact CG-CH2 4.48Å; F502-W621 HydrophobicContact CZ-CH2 4.49Å; K529-W621 PolarHBondContact NZ-O 3.43Å; Q615-W621 PolarHBondContact O-NE1 3.15Å; L618-W621 PolarHBondContact O-N 3.32Å
622	L	80.3	Confident	78.6	Confident	125 Å²	125	84.5 Å²	84.5	65%	0.654	40%	0.398	S	S	*	.	H	α-helix	trans	-87.3	-18	179.6	-69.9	178.2	0	0	0	114.1	L618 R619	L618-L622 HydrophobicContact CD2-CD1 3.37Å; L618-L622 HydrophobicContact CD2-CG 3.86Å; L618-L622 WeakPolarHBondContact O-CG 3.15Å; L618-L622 PolarHBondContact O-N 3.12Å; L618-L622 VanDerWaalsContact O-N 3.12Å; R619-L622 PolarHBondContact O-N 3.22Å
623	A	79.1	Confident	78.8	Confident	21 Å²	21	81.5 Å²	81.5	17%	0.174	38%	0.377	C	S	.	.			trans	-70.1	133.3	-175.3	0	0	0	0	0	113.1	D506 K529 R619	D506-A623 VanDerWaalsContact CG-CB 3.48Å; D506-A623 WeakPolarHBondContact OD2-CB 3.29Å; K529-A623 PolarHBondContact NZ-O 2.55Å; R619-A623 VanDerWaalsContact O-CB 3.32Å; R619-A623 WeakPolarHBondContact O-CB 3.09Å; R619-A623 PolarHBondContact O-N 2.79Å
624	I	73.1	Confident	78.9	Confident	66 Å²	66	87.5 Å²	87.5	34%	0.338	40%	0.404	S	S	.	.			trans	-114.8	0	-179.5	-63.1	177.6	0	0	0	108.4	V505 L522 R525 L526 K529 F530	V505-I624 WeakPolarHBondContact CG1-OXT 3.16Å; L522-I624 HydrophobicContact CD1-CG2 3.78Å; R525-I624 HydrophobicContact CB-CG2 4.46Å; R525-I624 WeakPolarHBondContact CB-OXT 3.15Å; R525-I624 PolarHBondContact NE-O 3.42Å; R525-I624 PolarHBondContact NE-OXT 3.28Å; R525-I624 PolarHBondContact NH1-O 3.08Å; R525-I624 PolarHBondContact NH2-O 3.18Å; R525-I624 PolarHBondContact NH2-OXT 3.25Å; L526-I624 HydrophobicContact CD2-CD1 4.18Å; L526-I624 HydrophobicContact CD2-CG2 3.67Å; L526-I624 HydrophobicContact CG-CG2 4.14Å; K529-I624 HydrophobicContact CD-CG1 4.48Å; F530-I624 HydrophobicContact CE2-CD1 3.87Å; F530-I624 HydrophobicContact CE2-CG1 4.05Å

Retrieved 624 of 624 residues in 585.7 ms (Link to these results)

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