A0A087YFH4_POEFO Loading...

Transmembrane protein 39A

AlphaFold DB , UniProt , Accession A0A087YFH4, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 494 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	41.7	Very low	36	Very low	240 Å²	240	160.9 Å²	160.9	100%	1.182	89%	0.885	S	S	*	*				0	124	0	-73.9	-173.9	145.1	0	0	108.7
2	P	41	Very low	35.4	Very low	135 Å²	135	164.4 Å²	164.4	88%	0.877	89%	0.89	S	S	*	*			trans	-73.6	158.6	166.5	35	-30.7	0	0	0	107.7
3	G	38.7	Very low	34.9	Very low	82 Å²	82	163.5 Å²	163.5	85%	0.845	88%	0.883	S	S	*	*			cis	134.1	116.6	27.6	0	0	0	0	0	105.5
4	G	36.3	Very low	34.3	Very low	84 Å²	84	160.1 Å²	160.1	87%	0.866	88%	0.878	S	S	*	*			trans	-154	120	-176.7	0	0	0	0	0	112.4
5	R	37.7	Very low	34	Very low	252 Å²	252	165.7 Å²	165.7	95%	0.951	88%	0.881	S	S	*	*			trans	-86	151.8	-161.3	-83.2	169.8	161	173	-6.5	115.6
6	R	38.5	Very low	33.5	Very low	253 Å²	253	162.4 Å²	162.4	96%	0.955	88%	0.875	S	S	*	*			trans	-18.1	140.5	153.4	-66.6	174.3	175	175.4	-2.1	120.2
7	G	33	Very low	33.2	Very low	72 Å²	72	159.9 Å²	159.9	74%	0.742	87%	0.873	S	S	*	*				115.6	164	128.1	0	0	0	0	0	119.1
8	P	42	Very low	32.9	Very low	121 Å²	121	160.1 Å²	160.1	79%	0.786	87%	0.872	S	S	*	*				-130.5	166.5	-99.9	39.6	-26.8	0	0	0	118
9	S	30.3	Very low	32.7	Very low	114 Å²	114	157.8 Å²	157.8	80%	0.797	87%	0.866	S	S	*	*			trans	45.4	124.3	147.7	60.9	0	0	0	0	122.3
10	R	29.4	Very low	32.4	Very low	243 Å²	243	155.4 Å²	155.4	92%	0.917	86%	0.861	S	S	*	*			trans	-144.2	133.3	142.3	-144	176.9	-173.9	-149.7	1.9	112.7
11	Q	27.8	Very low	32.3	Very low	174 Å²	174	156.4 Å²	156.4	81%	0.813	86%	0.864	S	S	*	*			trans	-60	133.2	-173.8	-63.1	148.9	-32.3	0	0	113.1
12	Q	28.1	Very low	31.7	Very low	203 Å²	203	153.4 Å²	153.4	95%	0.949	85%	0.847	S	S	*	*			trans	-89.9	105.5	156.1	-87.2	-171.5	-47.1	0	0	108.6	S14	Q12-S14 PolarHBondContact O-N 3.29Å
13	L	29.4	Very low	31.1	Very low	153 Å²	153	153.3 Å²	153.3	80%	0.801	84%	0.844	S	S	*	*	P	Polyproline II helix	trans	-63.1	123.4	167.2	-83.7	142.2	0	0	0	109.8	R15	L13-R15 PolarHBondContact O-N 3.38Å
14	S	26.6	Very low	30.5	Very low	116 Å²	116	157.1 Å²	157.1	81%	0.811	84%	0.844	S	S	*	*	P	Polyproline II helix	trans	-48	122.5	163.2	32.4	0	0	0	0	111.1	Q12	Q12-S14 PolarHBondContact O-N 3.29Å
15	R	28.9	Very low	30.2	Very low	244 Å²	244	159.7 Å²	159.7	92%	0.921	84%	0.843	S	S	*	*	P	Polyproline II helix	trans	-100.3	123.9	160.7	-87.4	-172.3	175.1	-169.6	-0.7	109.1	L13	L13-R15 PolarHBondContact O-N 3.38Å
16	S	26.8	Very low	29.7	Very low	113 Å²	113	151.5 Å²	151.5	79%	0.79	84%	0.837	S	S	*	*			trans	-44.7	122.3	174.4	37.2	0	0	0	0	113.9
17	S	28	Very low	29.2	Very low	119 Å²	119	142.9 Å²	142.9	83%	0.832	83%	0.826	S	S	*	*	P	Polyproline II helix	trans	-76.1	121.7	158	41.8	0	0	0	0	109.1
18	L	28.7	Very low	28.9	Very low	164 Å²	164	144.7 Å²	144.7	86%	0.859	83%	0.828	S	S	*	*	P	Polyproline II helix	trans	-83	151.6	161.5	-83.9	157.3	0	0	0	109.2
19	P	28.8	Very low	28.4	Very low	116 Å²	116	145.4 Å²	145.4	75%	0.753	83%	0.83	S	S	*	*	P	Polyproline II helix	trans	-89	147	-156	23.6	-12.5	0	0	0	113.7
20	S	26	Very low	28.3	Very low	110 Å²	110	145.5 Å²	145.5	77%	0.769	83%	0.831	S	S	*	*	P	Polyproline II helix	trans	-72.5	121.7	166.6	54.7	0	0	0	0	110.3	Q22	S20-Q22 PolarHBondContact O-N 2.72Å
21	L	29.6	Very low	28.4	Very low	176 Å²	176	142.2 Å²	142.2	92%	0.921	83%	0.831	S	S	*	*			trans	-67.9	90.3	167.9	-97.1	162.9	0	0	0	110.1
22	Q	30.5	Very low	28.5	Very low	178 Å²	178	137.7 Å²	137.7	83%	0.832	83%	0.831	S	S	*	*			trans	-141.5	86.6	157	-78.2	-170.2	-13.7	0	0	108.8	S20	S20-Q22 PolarHBondContact O-N 2.72Å
23	T	28.7	Very low	28.5	Very low	133 Å²	133	137 Å²	137	82%	0.816	83%	0.83	S	S	*	*			trans	-152.2	102.2	158.6	-38.1	0	0	0	0	108.8
24	L	26.1	Very low	28.5	Very low	161 Å²	161	132.7 Å²	132.7	84%	0.843	82%	0.823	S	S	*	*			trans	-163.1	134.5	136.2	-137.9	75.9	0	0	0	110.5
25	V	29.7	Very low	28.7	Very low	138 Å²	138	136 Å²	136	84%	0.836	83%	0.83	S	S	*	*			trans	76.6	107	174.4	-159.8	0	0	0	0	113.3
26	G	27	Very low	28.8	Very low	80 Å²	80	135.4 Å²	135.4	83%	0.825	83%	0.828	S	S	*	*			cis	119.1	108	23.2	0	0	0	0	0	108.1
27	G	27.7	Very low	28.9	Very low	72 Å²	72	137 Å²	137	74%	0.742	83%	0.828	S	S	*	*			trans	155.1	84.7	172.2	0	0	0	0	0	117.7
28	S	26.5	Very low	28.9	Very low	111 Å²	111	142.1 Å²	142.1	78%	0.776	83%	0.829	S	S	*	*			trans	36.2	119.1	137.4	55.7	0	0	0	0	124
29	V	31.2	Very low	28.9	Very low	136 Å²	136	139.9 Å²	139.9	82%	0.824	83%	0.827	S	S	*	*				56.9	114.8	127.6	-162.2	0	0	0	0	120.8
30	S	28.2	Very low	28.9	Very low	116 Å²	116	139.2 Å²	139.2	81%	0.811	83%	0.825	S	S	*	*				167.1	138.5	111	47.4	0	0	0	0	113.5
31	N	31.8	Very low	29.5	Very low	174 Å²	174	142.8 Å²	142.8	93%	0.93	84%	0.835	S	S	*	*			trans	-73.6	146.9	169.4	-82.8	-23.2	0	0	0	111.2
32	G	29.4	Very low	29.6	Very low	78 Å²	78	139.1 Å²	139.1	80%	0.804	82%	0.824	S	S	*	*			trans	-173.3	111.2	169.6	0	0	0	0	0	113.9
33	M	28.6	Very low	30	Very low	189 Å²	189	137.9 Å²	137.9	93%	0.931	83%	0.828	S	S	*	*			trans	-65.6	139.5	176.1	-172	92.8	73.6	0	0	112.5
34	G	30.6	Very low	30	Very low	63 Å²	63	134.3 Å²	134.3	65%	0.649	82%	0.818	S	S	*	*			trans	53.5	126.8	144.7	0	0	0	0	0	120.6
35	L	29.6	Very low	30.2	Very low	184 Å²	184	134.8 Å²	134.8	96%	0.963	82%	0.821	S	S	*	*				-174.1	152.2	123.9	-99.6	161.4	0	0	0	112.1
36	R	30.7	Very low	30.3	Very low	232 Å²	232	133.5 Å²	133.5	88%	0.875	82%	0.818	S	S	*	*			trans	-91.2	145.2	-170.9	-152.3	178.3	-174.9	175.7	0.5	109.2
37	N	28.9	Very low	30.6	Very low	147 Å²	147	133.8 Å²	133.8	79%	0.786	81%	0.813	S	S	*	*			trans	74.3	114.8	147.2	-147.1	30.2	0	0	0	119.1
38	R	28.1	Very low	31	Very low	227 Å²	227	134.7 Å²	134.7	86%	0.857	81%	0.805	S	S	*	*				-178.7	132.4	115.9	-112	175.6	167.6	172.2	-4.2	111.9	S40	R38-S40 PolarHBondContact O-N 3.39Å
39	S	30.3	Very low	31.5	Very low	117 Å²	117	133.7 Å²	133.7	82%	0.818	80%	0.796	S	S	*	*			trans	-45	123.9	159	49.4	0	0	0	0	112.1
40	S	28.9	Very low	32.1	Very low	101 Å²	101	133.5 Å²	133.5	71%	0.706	79%	0.789	S	S	*	*			trans	-134.4	120.5	157.5	57.1	0	0	0	0	108.8	R38 S42	R38-S40 PolarHBondContact O-N 3.39Å; S40-S42 PolarHBondContact O-N 3.36Å
41	N	38.3	Very low	32.8	Very low	185 Å²	185	130.7 Å²	130.7	99%	0.989	77%	0.769	S	S	*	*			trans	-68.6	104.8	165.3	-95.4	-2.2	0	0	0	107.3
42	S	31.6	Very low	33	Very low	99 Å²	99	126.6 Å²	126.6	69%	0.692	75%	0.751	S	S	*	*			trans	-120.1	118.1	160.4	59.4	0	0	0	0	107.7	S40 G44	S40-S42 PolarHBondContact O-N 3.36Å; S42-G44 PolarHBondContact O-N 2.68Å
43	V	38.4	Very low	33.5	Very low	152 Å²	152	129.7 Å²	129.7	92%	0.921	75%	0.748	S	S	*	*			trans	-61.3	88.1	164.5	175.9	0	0	0	0	106.7
44	G	27.6	Very low	34.2	Very low	58 Å²	58	125.6 Å²	125.6	60%	0.598	73%	0.729	S	S	*	*			trans	-91.9	119.7	172.5	0	0	0	0	0	107.9	S42 S46	S42-G44 PolarHBondContact O-N 2.68Å; G44-S46 PolarHBondContact O-N 2.98Å; G44-S46 VanDerWaalsContact O-N 3.12Å
45	L	31.6	Very low	34.7	Very low	171 Å²	171	128.2 Å²	128.2	90%	0.895	73%	0.733	S	S	*	*			trans	-45.3	122.2	164.4	-74.6	96.9	0	0	0	108.2	A47	L45-A47 PolarHBondContact O-N 2.82Å
46	S	31.3	Very low	35.8	Very low	112 Å²	112	121 Å²	121	78%	0.783	70%	0.697	S	S	*	*			trans	-53.6	113.2	173	51.3	0	0	0	0	108.4	G44	G44-S46 PolarHBondContact O-N 2.98Å; G44-S46 VanDerWaalsContact O-N 3.12Å
47	A	33.4	Very low	36.6	Very low	86 Å²	86	117.2 Å²	117.2	71%	0.711	69%	0.689	S	S	*	*	P	Polyproline II helix	trans	-50.7	132.6	166.8	0	0	0	0	0	107.8	L45	L45-A47 PolarHBondContact O-N 2.82Å
48	P	35.6	Very low	37.7	Very low	91 Å²	91	114.4 Å²	114.4	59%	0.591	68%	0.679	S	S	*	*	P	Polyproline II helix	trans	-59.5	142.8	178.8	25.7	-32.1	0	0	0	108.3	I50	P48-I50 PolarHBondContact O-N 3.31Å
49	P	38.6	Very low	38.9	Very low	90 Å²	90	105 Å²	105	58%	0.584	65%	0.646	S	S	*	*	P	Polyproline II helix	trans	-57.8	129.2	177.3	24.3	-32	0	0	0	108.4	S51 T52	P49-S51 PolarHBondContact O-N 3.05Å; P49-T52 PolarHBondContact O-N 3.16Å; P49-T52 PolarHBondContact O-OG1 3.17Å
50	I	42.9	Very low	39.9	Very low	132 Å²	132	108.2 Å²	108.2	68%	0.677	64%	0.641	S	S	*	*	G	3₁₀ helix	trans	-55.2	-12.8	179.2	-63.9	170.3	0	0	0	112.4	P48 T52 L53	P48-I50 PolarHBondContact O-N 3.31Å; I50-T52 PolarHBondContact O-N 3.37Å; I50-T52 VanDerWaalsContact O-N 3.11Å; I50-L53 HydrophobicContact CG2-CB 4.49Å; I50-L53 PolarHBondContact O-N 3Å
51	S	42.6	Very low	41.4	Very low	56 Å²	56	106 Å²	106	39%	0.392	62%	0.619	S	S	.	*	G	3₁₀ helix	trans	-52.6	-22.5	163.6	178	0	0	0	0	114.4	P49	P49-S51 PolarHBondContact O-N 3.05Å
52	T	36.4	Very low	42.1	Very low	89 Å²	89	98.6 Å²	98.6	55%	0.546	58%	0.582	S	S	.	*	G	3₁₀ helix	trans	-83.7	-13.1	175.6	52.9	0	0	0	0	113.2	P49 I50	P49-T52 PolarHBondContact O-N 3.16Å; P49-T52 PolarHBondContact O-OG1 3.17Å; I50-T52 PolarHBondContact O-N 3.37Å; I50-T52 VanDerWaalsContact O-N 3.11Å
53	L	39.1	Very low	43.1	Very low	142 Å²	142	105.4 Å²	105.4	74%	0.743	59%	0.592	S	S	*	*	T	Hydrogen-bonded Turn	trans	-100.6	-10.7	-173	-135.9	93.7	0	0	0	114.4	I50	I50-L53 HydrophobicContact CG2-CB 4.49Å; I50-L53 PolarHBondContact O-N 3Å
54	I	44.8	Very low	44	Very low	103 Å²	103	99.6 Å²	99.6	53%	0.528	56%	0.556	S	S	.	*			trans	-107.6	79.5	172.4	-52	173.9	0	0	0	106.5	P56 P383	I54-P56 VanDerWaalsContact O-CD 3.29Å; I54-P56 WeakPolarHBondContact O-CD 3.14Å; I54-P383 HydrophobicContact CG2-CB 4.29Å; I54-P383 HydrophobicContact CG2-CG 4.21Å
55	T	40.8	Very low	45.1	Very low	119 Å²	119	100.8 Å²	100.8	73%	0.73	55%	0.553	S	S	*	*	P	Polyproline II helix	trans	-61.4	118.9	166	43	0	0	0	0	107.3	E57	T55-E57 PolarHBondContact O-N 3.38Å
56	P	52.6	Low	46	Very low	32 Å²	32	102 Å²	102	21%	0.208	55%	0.554	C	S	.	*	P	Polyproline II helix	trans	-58.3	135.7	174.1	23.4	-32.2	0	0	0	108.9	I54 V381 Y401	I54-P56 VanDerWaalsContact O-CD 3.29Å; I54-P56 WeakPolarHBondContact O-CD 3.14Å; P56-V381 HydrophobicContact CG-CG1 4.14Å; P56-Y401 HydrophobicContact CB-CD1 4.1Å; P56-Y401 HydrophobicContact CB-CD2 4.5Å; P56-Y401 HydrophobicContact CB-CE1 3.69Å; P56-Y401 HydrophobicContact CB-CE2 4.15Å; P56-Y401 HydrophobicContact CB-CG 4.47Å; P56-Y401 HydrophobicContact CG-CD1 3.85Å; P56-Y401 HydrophobicContact CG-CE1 3.33Å; P56-Y401 PolarHBondContact O-OH 3.19Å
57	E	46.5	Very low	47.1	Very low	152 Å²	152	98.1 Å²	98.1	71%	0.71	53%	0.525	S	S	*	.	P	Polyproline II helix	trans	-58.2	132.2	177.2	-78.5	-163.9	140.2	0	0	110.1	T55 V59 Y401	T55-E57 PolarHBondContact O-N 3.38Å; E57-V59 PolarHBondContact O-N 3.48Å; E57-Y401 WeakPolarHBondContact O-CE2 3.41Å; E57-Y401 PolarHBondContact O-OH 2.85Å
58	P	51.8	Low	47.8	Very low	89 Å²	89	98.9 Å²	98.9	58%	0.578	52%	0.522	S	S	*	.	P	Polyproline II helix	trans	-49.5	130.5	-177.5	20.1	-31.9	0	0	0	112.1	R60 Y401	P58-R60 PolarHBondContact O-N 2.83Å; P58-Y401 WeakPolarHBondContact CA-OH 2.79Å
59	V	54.5	Low	48.8	Very low	28 Å²	28	100.7 Å²	100.7	17%	0.17	53%	0.526	C	S	.	.			trans	-59.5	104.9	170.6	-175.8	0	0	0	0	107.6	E57 H61 A354 H355 Y401	E57-V59 PolarHBondContact O-N 3.48Å; V59-H61 PolarHBondContact O-N 3.16Å; V59-A354 HydrophobicContact CG1-CB 3.99Å; V59-H355 WeakPolarHBondContact CG2-ND1 3.45Å; V59-Y401 HydrophobicContact CB-CD2 4.48Å; V59-Y401 HydrophobicContact CB-CE2 4.25Å; V59-Y401 HydrophobicContact CG2-CD2 3.11Å; V59-Y401 HydrophobicContact CG2-CE2 3.22Å; V59-Y401 HydrophobicContact CG2-CG 4.04Å
60	R	50.5	Low	49.8	Very low	186 Å²	186	98.8 Å²	98.8	70%	0.702	51%	0.511	S	S	*	.	P	Polyproline II helix	trans	-78.9	116.3	178.1	-66.8	-174.9	-172.5	158.9	6.2	108.9	P58	P58-R60 PolarHBondContact O-N 2.83Å
61	H	59.6	Low	51.2	Low	53 Å²	53	95.1 Å²	95.1	25%	0.245	50%	0.497	C	S	.	.	P	Polyproline II helix	trans	-86.1	126	176.9	-57.4	-55.9	0	0	0	110.3	V59 R63 R351 H355	V59-H61 PolarHBondContact O-N 3.16Å; H61-R63 PolarHBondContact O-N 2.88Å; H61-R351 WeakPolarHBondContact ND1-CG 3.44Å; H61-H355 AromaticContact CE1-CE1 3.91Å; H61-H355 AromaticContact CE1-NE2 3.34Å; H61-H355 PolarHBondContact CE1-NE2 3.41Å; H61-H355 VanDerWaalsContact CE1-NE2 3.34Å; H61-H355 AromaticContact NE2-CE1 3.8Å; H61-H355 AromaticContact NE2-NE2 3.29Å; H61-H355 PolarHBondContact NE2-NE2 3.37Å
62	S	54.1	Low	52.9	Low	30 Å²	30	94.2 Å²	94.2	21%	0.21	49%	0.491	C	S	.	.	P	Polyproline II helix	trans	-68.8	122.1	167.1	45.3	0	0	0	0	109	I64 Y480	S62-I64 PolarHBondContact O-N 3.36Å; S62-I64 VanDerWaalsContact O-N 3.16Å; S62-Y480 VanDerWaalsContact OG-CD1 3.31Å; S62-Y480 WeakPolarHBondContact OG-CD1 3.48Å; S62-Y480 WeakPolarHBondContact OG-CE1 3.15Å
63	R	52.9	Low	55.1	Low	243 Å²	243	93.8 Å²	93.8	92%	0.917	48%	0.482	S	S	*	.			trans	-74.8	104.5	176.4	-167.2	176.3	-173.3	174.7	1.9	108.8	H61	H61-R63 PolarHBondContact O-N 2.88Å
64	I	57	Low	57.3	Low	29 Å²	29	91 Å²	91	15%	0.149	47%	0.467	C	S	.	.			trans	-72.7	136.1	177.5	-52.9	173.1	0	0	0	108.1	S62 D347 L476 A479 Y480	S62-I64 PolarHBondContact O-N 3.36Å; S62-I64 VanDerWaalsContact O-N 3.16Å; I64-D347 HydrophobicContact CD1-CB 3.57Å; I64-D347 WeakPolarHBondContact CD1-OD1 3.07Å; I64-L476 HydrophobicContact CD1-CD1 3.86Å; I64-L476 HydrophobicContact CG2-CD1 4.18Å; I64-A479 HydrophobicContact CG1-CB 4.45Å; I64-A479 HydrophobicContact CG2-CB 4.12Å; I64-Y480 HydrophobicContact CD1-CE1 4.4Å; I64-Y480 HydrophobicContact CD1-CE2 4.22Å; I64-Y480 WeakPolarHBondContact CD1-OH 3.45Å
65	P	51.2	Low	59.3	Low	84 Å²	84	86.5 Å²	86.5	55%	0.545	44%	0.444	S	S	.	.			trans	-59.1	140.8	169	-14.8	26.5	0	0	0	109.7	L67	P65-L67 VanDerWaalsContact C-N 3.34Å; P65-L67 PolarHBondContact O-N 2.87Å
66	E	49.5	Very low	61.6	Low	195 Å²	195	81.3 Å²	81.3	91%	0.911	41%	0.411	S	S	*	.			trans	-63.3	99.3	170.6	-68.4	-177.9	-176.8	0	0	108.4
67	L	53.7	Low	63.4	Low	32 Å²	32	84.1 Å²	84.1	17%	0.168	42%	0.42	C	S	.	.			trans	-59	136.2	169.2	-84.6	151.5	0	0	0	107.4	P65 L69 P343 V475	P65-L67 VanDerWaalsContact C-N 3.34Å; P65-L67 PolarHBondContact O-N 2.87Å; L67-L69 PolarHBondContact O-N 2.76Å; L67-P343 HydrophobicContact CD1-CB 3.94Å; L67-P343 HydrophobicContact CD1-CG 3.99Å; L67-V475 HydrophobicContact CD1-CG1 4.16Å; L67-V475 HydrophobicContact CD2-CB 3.82Å; L67-V475 HydrophobicContact CD2-CG1 3.5Å; L67-V475 VanDerWaalsContact CD2-CG1 3.5Å; L67-V475 HydrophobicContact CD2-CG2 4.03Å; L67-V475 HydrophobicContact CG-CG1 3.93Å
68	P	49.5	Very low	65.5	Low	102 Å²	102	78.9 Å²	78.9	66%	0.662	40%	0.397	S	S	*	.			trans	-58.4	108.7	173.3	24.9	-31.9	0	0	0	107.4	D70	P68-D70 PolarHBondContact O-N 2.96Å
69	L	56	Low	67.3	Low	128 Å²	128	74.8 Å²	74.8	67%	0.67	37%	0.37	S	S	*	.	P	Polyproline II helix	trans	-64.9	119.6	171.2	-68.3	167.6	0	0	0	105.5	L67 S71 P342	L67-L69 PolarHBondContact O-N 2.76Å; L69-S71 PolarHBondContact O-N 3.12Å; L69-P342 HydrophobicContact CD2-CB 4.33Å
70	D	59.3	Low	69.2	Low	50 Å²	50	75.2 Å²	75.2	27%	0.267	37%	0.37	S	S	.	.	P	Polyproline II helix	trans	-52.5	129.6	167.4	-75.1	-16.8	0	0	0	106.9	P68 S72 K468	P68-D70 PolarHBondContact O-N 2.96Å; D70-S72 PolarHBondContact O-N 3.02Å; D70-K468 WeakPolarHBondContact OD2-CE 3.46Å; D70-K468 IonicContact OD2-NZ 3.62Å; D70-K468 PolarHBondContact OD2-NZ 2.99Å
71	S	72.4	Confident	71.2	Confident	55 Å²	55	70 Å²	70	39%	0.385	36%	0.356	S	S	.	.	P	Polyproline II helix	trans	-53.1	137.1	176.6	61.7	0	0	0	0	109	L69 F73 L74 F75	L69-S71 PolarHBondContact O-N 3.12Å; S71-F73 PolarHBondContact O-N 3.32Å; S71-L74 PolarHBondContact O-N 3.06Å; S71-L74 WeakPolarHBondContact OG-CB 3.47Å; S71-L74 WeakPolarHBondContact OG-CD1 3.32Å; S71-L74 WeakPolarHBondContact OG-CG 3.29Å; S71-L74 PolarHBondContact OG-N 3.46Å; S71-F75 PolarHBondContact O-N 2.82Å
72	S	79	Confident	72.8	Confident	38 Å²	38	67.9 Å²	67.9	27%	0.266	35%	0.345	S	S	.	.	H	α-helix	trans	-49	-37	-179.8	-49.9	0	0	0	0	111.6	D70 E76 E140	D70-S72 PolarHBondContact O-N 3.02Å; S72-E76 WeakPolarHBondContact O-CG 3.31Å; S72-E76 PolarHBondContact O-N 3.47Å; S72-E76 VanDerWaalsContact O-N 3.15Å; S72-E140 WeakPolarHBondContact CB-OE1 3.3Å
73	F	82.9	Confident	74.7	Confident	80 Å²	80	66.7 Å²	66.7	35%	0.351	34%	0.337	S	S	.	.	H	α-helix	trans	-59.4	-51.3	174	176.5	-101.5	0	0	0	114.1	S71 F75 E76 F77 L133 T136 I137	S71-F73 PolarHBondContact O-N 3.32Å; F73-F75 VanDerWaalsContact C-N 3.28Å; F73-F75 PolarHBondContact O-N 2.95Å; F73-E76 PolarHBondContact O-N 3.25Å; F73-F77 VanDerWaalsContact O-CB 3.31Å; F73-F77 WeakPolarHBondContact O-CB 3.17Å; F73-F77 PolarHBondContact O-N 2.9Å; F73-L133 HydrophobicContact CD2-CD1 4.14Å; F73-L133 HydrophobicContact CE2-CD1 3.83Å; F73-T136 HydrophobicContact CB-CG2 4.46Å; F73-I137 HydrophobicContact CD2-CG1 3.8Å; F73-I137 HydrophobicContact CE2-CD1 3.94Å; F73-I137 HydrophobicContact CE2-CG1 3.49Å; F73-I137 VanDerWaalsContact CE2-CG1 3.49Å
74	L	85.1	Confident	76.7	Confident	83 Å²	83	58.3 Å²	58.3	44%	0.435	31%	0.31	S	S	.	.	H	α-helix	trans	-60.7	-39	-179.8	-76.6	174.8	0	0	0	111.7	S71 F77 L78	S71-L74 PolarHBondContact O-N 3.06Å; S71-L74 WeakPolarHBondContact OG-CB 3.47Å; S71-L74 WeakPolarHBondContact OG-CD1 3.32Å; S71-L74 WeakPolarHBondContact OG-CG 3.29Å; S71-L74 PolarHBondContact OG-N 3.46Å; L74-F77 PolarHBondContact O-N 3.5Å; L74-L78 WeakPolarHBondContact O-CB 3.31Å; L74-L78 WeakPolarHBondContact O-CD1 2.99Å; L74-L78 VanDerWaalsContact O-CG 3.23Å; L74-L78 WeakPolarHBondContact O-CG 3.37Å; L74-L78 PolarHBondContact O-N 3.38Å
75	F	87.3	Confident	78.5	Confident	9 Å²	9	58.5 Å²	58.5	4%	0.039	31%	0.312	C	S	.	.	H	α-helix	trans	-62.2	-51.7	175.7	173.6	-86.9	0	0	0	111.7	S71 F73 F77 L78 L79 M335 L336 Q339	S71-F75 PolarHBondContact O-N 2.82Å; F73-F75 VanDerWaalsContact C-N 3.28Å; F73-F75 PolarHBondContact O-N 2.95Å; F75-F77 PolarHBondContact O-N 3.23Å; F75-L78 PolarHBondContact O-N 3.43Å; F75-L79 HydrophobicContact CE1-CB 4.3Å; F75-L79 HydrophobicContact CE1-CD2 4.08Å; F75-L79 WeakPolarHBondContact O-CB 3.4Å; F75-L79 PolarHBondContact O-N 2.93Å; F75-M335 HydrophobicContact CE2-CB 4.4Å; F75-M335 WeakPolarHBondContact CE2-O 3.31Å; F75-M335 HydrophobicContact CZ-CB 4.33Å; F75-M335 WeakPolarHBondContact CZ-O 3.48Å; F75-L336 HydrophobicContact CE1-CD2 4.29Å; F75-L336 HydrophobicContact CZ-CD2 4.32Å; F75-Q339 HydrophobicContact CD1-CB 4.1Å; F75-Q339 HydrophobicContact CD1-CG 3.76Å; F75-Q339 HydrophobicContact CD2-CB 4Å; F75-Q339 HydrophobicContact CD2-CG 4.21Å; F75-Q339 HydrophobicContact CE1-CB 3.84Å; F75-Q339 HydrophobicContact CE1-CG 3.94Å; F75-Q339 HydrophobicContact CE2-CB 3.71Å; F75-Q339 HydrophobicContact CE2-CG 4.36Å; F75-Q339 HydrophobicContact CG-CB 4.18Å; F75-Q339 HydrophobicContact CG-CG 3.9Å; F75-Q339 HydrophobicContact CZ-CB 3.62Å; F75-Q339 HydrophobicContact CZ-CG 4.22Å
76	E	88.6	Confident	80.5	Confident	10 Å²	10	54.5 Å²	54.5	5%	0.047	29%	0.286	C	S	.	.	H	α-helix	trans	-64.3	-34.1	-178.3	-67.5	-72	171.6	0	0	111.2	S72 F73 F80 R132 L133 T136 Q339	S72-E76 WeakPolarHBondContact O-CG 3.31Å; S72-E76 PolarHBondContact O-N 3.47Å; S72-E76 VanDerWaalsContact O-N 3.15Å; F73-E76 PolarHBondContact O-N 3.25Å; E76-F80 VanDerWaalsContact O-CB 3.29Å; E76-F80 WeakPolarHBondContact O-CB 3.36Å; E76-F80 PolarHBondContact O-N 3.11Å; E76-R132 IonicContact OE1-CZ 3.61Å; E76-R132 IonicContact OE1-NE 3.63Å; E76-R132 IonicContact OE1-NH2 3.03Å; E76-R132 PolarHBondContact OE1-NH2 2.85Å; E76-R132 WeakPolarHBondContact OE2-CB 3.46Å; E76-R132 IonicContact OE2-CZ 2.72Å; E76-R132 IonicContact OE2-NE 2.74Å; E76-R132 PolarHBondContact OE2-NE 2.86Å; E76-R132 VanDerWaalsContact OE2-NE 3.07Å; E76-R132 IonicContact OE2-NH2 4Å; E76-R132 PolarHBondContact OE2-NH2 3.19Å; E76-L133 HydrophobicContact CB-CD1 4.2Å; E76-T136 HydrophobicContact CG-CG2 4.28Å; E76-Q339 PolarHBondContact OE1-NE2 3.2Å
77	F	89.8	Confident	82.6	Confident	90 Å²	90	45.5 Å²	45.5	40%	0.395	24%	0.244	S	C	.	.	H	α-helix	trans	-64.5	-46.2	173.2	176.8	-101.5	0	0	0	112.2	F73 L74 F75 F80 L81 L133	F73-F77 VanDerWaalsContact O-CB 3.31Å; F73-F77 WeakPolarHBondContact O-CB 3.17Å; F73-F77 PolarHBondContact O-N 2.9Å; L74-F77 PolarHBondContact O-N 3.5Å; F75-F77 PolarHBondContact O-N 3.23Å; F77-F80 PolarHBondContact O-N 2.93Å; F77-L81 WeakPolarHBondContact O-CB 3.27Å; F77-L81 PolarHBondContact O-N 3.44Å; F77-L133 HydrophobicContact CB-CD1 4.09Å; F77-L133 HydrophobicContact CD2-CD2 4.41Å
78	L	90.2	Very high	84.4	Confident	43 Å²	43	49.1 Å²	49.1	23%	0.225	26%	0.259	C	S	.	.	H	α-helix	trans	-65.5	-39.6	177.5	-72.9	165.9	0	0	0	112	L74 F75 L81 Y82 Y464	L74-L78 WeakPolarHBondContact O-CB 3.31Å; L74-L78 WeakPolarHBondContact O-CD1 2.99Å; L74-L78 VanDerWaalsContact O-CG 3.23Å; L74-L78 WeakPolarHBondContact O-CG 3.37Å; L74-L78 PolarHBondContact O-N 3.38Å; F75-L78 PolarHBondContact O-N 3.43Å; L78-L81 PolarHBondContact O-N 3.42Å; L78-Y82 WeakPolarHBondContact O-CB 3.45Å; L78-Y82 PolarHBondContact O-N 3.06Å; L78-Y464 HydrophobicContact CD1-CE1 3.69Å; L78-Y464 WeakPolarHBondContact CD1-OH 3.3Å; L78-Y464 HydrophobicContact CD2-CE1 4.37Å
79	L	91.1	Very high	86.4	Confident	3 Å²	3	44.2 Å²	44.2	2%	0.016	23%	0.227	C	C	.	.	H	α-helix	trans	-62.1	-46	173.1	-179.5	67.4	0	0	0	110.9	F75 Y82 L83 M335 L336	F75-L79 HydrophobicContact CE1-CB 4.3Å; F75-L79 HydrophobicContact CE1-CD2 4.08Å; F75-L79 WeakPolarHBondContact O-CB 3.4Å; F75-L79 PolarHBondContact O-N 2.93Å; L79-Y82 HydrophobicContact CD1-CD1 4.5Å; L79-Y82 PolarHBondContact O-N 3.33Å; L79-L83 HydrophobicContact CD1-CD1 4.27Å; L79-L83 HydrophobicContact CD1-CG 4.45Å; L79-L83 HydrophobicContact CG-CD1 4.01Å; L79-L83 VanDerWaalsContact O-CG 3.25Å; L79-L83 WeakPolarHBondContact O-CG 3.37Å; L79-L83 PolarHBondContact O-N 3.23Å; L79-M335 HydrophobicContact CB-CE 4.16Å; L79-M335 HydrophobicContact CD1-CB 4.21Å; L79-M335 HydrophobicContact CD1-CE 4.06Å; L79-M335 HydrophobicContact CD1-SD 4.04Å; L79-L336 HydrophobicContact CD2-CD2 3.81Å; L79-L336 HydrophobicContact CD2-CG 4.43Å
80	F	92.8	Very high	88.1	Confident	36 Å²	36	38.1 Å²	38.1	16%	0.158	20%	0.195	C	C	.	.	H	α-helix	trans	-61.4	-45.3	176.9	176.4	-109.9	0	0	0	112	E76 F77 Y82 L83 L84 T126 L129 A130 L133	E76-F80 VanDerWaalsContact O-CB 3.29Å; E76-F80 WeakPolarHBondContact O-CB 3.36Å; E76-F80 PolarHBondContact O-N 3.11Å; F77-F80 PolarHBondContact O-N 2.93Å; F80-Y82 VanDerWaalsContact C-N 3.34Å; F80-Y82 PolarHBondContact O-N 2.85Å; F80-L83 PolarHBondContact O-N 2.69Å; F80-L84 WeakPolarHBondContact O-CB 3.45Å; F80-L84 PolarHBondContact O-N 2.7Å; F80-T126 HydrophobicContact CE2-CG2 4.46Å; F80-T126 HydrophobicContact CZ-CG2 4.18Å; F80-L129 HydrophobicContact CD2-CB 4.2Å; F80-L129 HydrophobicContact CE2-CB 4.14Å; F80-A130 HydrophobicContact CD2-CB 4.21Å; F80-A130 HydrophobicContact CE2-CB 3.62Å; F80-A130 HydrophobicContact CZ-CB 4.04Å; F80-L133 HydrophobicContact CB-CD2 4.14Å; F80-L133 HydrophobicContact CD1-CD2 3.73Å; F80-L133 HydrophobicContact CE1-CD2 4.37Å; F80-L133 HydrophobicContact CG-CD2 3.97Å
81	L	93.1	Very high	89.5	Confident	78 Å²	78	36.3 Å²	36.3	41%	0.408	19%	0.185	S	C	.	.	H	α-helix	trans	-59.8	-45.1	176.3	-178.8	65.2	0	0	0	111.3	F77 L78 L83 L84 V85	F77-L81 WeakPolarHBondContact O-CB 3.27Å; F77-L81 PolarHBondContact O-N 3.44Å; L78-L81 PolarHBondContact O-N 3.42Å; L81-L83 PolarHBondContact O-N 3.44Å; L81-L84 PolarHBondContact O-N 3.29Å; L81-V85 WeakPolarHBondContact O-CG2 3.4Å; L81-V85 PolarHBondContact O-N 2.9Å
82	Y	93.9	Very high	90.2	Very high	7 Å²	7	34 Å²	34	3%	0.027	17%	0.168	C	C	.	.	H	α-helix	trans	-58.6	-47.5	175.3	164.4	-106.3	0	0	0	112.1	L78 L79 F80 L84 V85 A86 V328 N331 A332 M335 I458 C461	L78-Y82 WeakPolarHBondContact O-CB 3.45Å; L78-Y82 PolarHBondContact O-N 3.06Å; L79-Y82 HydrophobicContact CD1-CD1 4.5Å; L79-Y82 PolarHBondContact O-N 3.33Å; F80-Y82 VanDerWaalsContact C-N 3.34Å; F80-Y82 PolarHBondContact O-N 2.85Å; Y82-L84 VanDerWaalsContact C-N 3.3Å; Y82-L84 PolarHBondContact O-N 3.34Å; Y82-V85 PolarHBondContact O-N 3.32Å; Y82-A86 WeakPolarHBondContact O-CB 3.1Å; Y82-A86 PolarHBondContact O-N 3.03Å; Y82-V328 WeakPolarHBondContact OH-CA 3.3Å; Y82-N331 WeakPolarHBondContact CE2-ND2 3.18Å; Y82-N331 WeakPolarHBondContact OH-CB 3.47Å; Y82-N331 PolarHBondContact OH-ND2 3.46Å; Y82-A332 HydrophobicContact CE1-CB 4.49Å; Y82-M335 HydrophobicContact CD1-SD 3.77Å; Y82-M335 HydrophobicContact CE1-SD 4.36Å; Y82-M335 HydrophobicContact CG-SD 3.94Å; Y82-I458 HydrophobicContact CE2-CG2 4.49Å; Y82-C461 HydrophobicContact CD2-CB 3.75Å; Y82-C461 HydrophobicContact CE2-CB 4.42Å
83	L	94.5	Very high	90.5	Very high	5 Å²	5	32.6 Å²	32.6	3%	0.026	16%	0.157	C	C	.	.	H	α-helix	trans	-65.8	-33.8	179.6	-65.9	170.1	0	0	0	112.1	L79 F80 L81 A86 L87 L129 V302	L79-L83 HydrophobicContact CD1-CD1 4.27Å; L79-L83 HydrophobicContact CD1-CG 4.45Å; L79-L83 HydrophobicContact CG-CD1 4.01Å; L79-L83 VanDerWaalsContact O-CG 3.25Å; L79-L83 WeakPolarHBondContact O-CG 3.37Å; L79-L83 PolarHBondContact O-N 3.23Å; F80-L83 PolarHBondContact O-N 2.69Å; L81-L83 PolarHBondContact O-N 3.44Å; L83-A86 PolarHBondContact O-N 3.21Å; L83-L87 VanDerWaalsContact O-CB 3.29Å; L83-L87 WeakPolarHBondContact O-CB 3.38Å; L83-L87 PolarHBondContact O-N 2.84Å; L83-L129 HydrophobicContact CB-CD1 4.16Å; L83-L129 HydrophobicContact CB-CD2 4.35Å; L83-L129 HydrophobicContact CD1-CD2 4.09Å; L83-V302 HydrophobicContact CB-CG2 4.18Å; L83-V302 HydrophobicContact CD2-CG2 3.98Å
84	L	94.4	Very high	90.6	Very high	67 Å²	67	28.8 Å²	28.8	35%	0.351	14%	0.141	S	C	.	.	H	α-helix	trans	-66	-44.5	173.4	-171.8	72.7	0	0	0	111.5	F80 L81 Y82 L87 F88 T126	F80-L84 WeakPolarHBondContact O-CB 3.45Å; F80-L84 PolarHBondContact O-N 2.7Å; L81-L84 PolarHBondContact O-N 3.29Å; Y82-L84 VanDerWaalsContact C-N 3.3Å; Y82-L84 PolarHBondContact O-N 3.34Å; L84-L87 PolarHBondContact O-N 3.11Å; L84-F88 WeakPolarHBondContact O-CB 3.4Å; L84-F88 PolarHBondContact O-N 3.36Å; L84-T126 HydrophobicContact CD1-CG2 4.19Å
85	V	94.2	Very high	90.5	Very high	33 Å²	33	25.4 Å²	25.4	20%	0.2	12%	0.122	C	C	.	.	H	α-helix	trans	-62.1	-45.2	174.6	171.7	0	0	0	0	110.4	L81 Y82 L87 F88 V89 L457	L81-V85 WeakPolarHBondContact O-CG2 3.4Å; L81-V85 PolarHBondContact O-N 2.9Å; Y82-V85 PolarHBondContact O-N 3.32Å; V85-L87 VanDerWaalsContact C-N 3.31Å; V85-L87 PolarHBondContact O-N 2.98Å; V85-F88 PolarHBondContact O-N 3.37Å; V85-V89 HydrophobicContact CG1-CG2 4.45Å; V85-V89 WeakPolarHBondContact O-CB 3.2Å; V85-V89 VanDerWaalsContact O-CG2 3.29Å; V85-V89 WeakPolarHBondContact O-CG2 3.42Å; V85-V89 PolarHBondContact O-N 3.4Å; V85-L457 HydrophobicContact CG1-CB 3.99Å
86	A	93.8	Very high	90	Very high	0 Å²	0	27.7 Å²	27.7	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-64.1	-35.3	178.4	0	0	0	0	0	112.8	Y82 L83 Q90 V302 H324 V328	Y82-A86 WeakPolarHBondContact O-CB 3.1Å; Y82-A86 PolarHBondContact O-N 3.03Å; L83-A86 PolarHBondContact O-N 3.21Å; A86-Q90 PolarHBondContact O-N 3.13Å; A86-V302 HydrophobicContact CB-CG1 3.65Å; A86-H324 PolarHBondContact O-NE2 2.83Å; A86-V328 HydrophobicContact CB-CG1 4.43Å; A86-V328 HydrophobicContact CB-CG2 3.82Å
87	L	93.8	Very high	89	Confident	6 Å²	6	27.7 Å²	27.7	3%	0.031	13%	0.131	C	C	.	.	H	α-helix	trans	-67.3	-47.4	173.9	-179.7	65.4	0	0	0	110.8	L83 L84 V85 V89 Q90 Y91 I125 L129 V302 P306	L83-L87 VanDerWaalsContact O-CB 3.29Å; L83-L87 WeakPolarHBondContact O-CB 3.38Å; L83-L87 PolarHBondContact O-N 2.84Å; L84-L87 PolarHBondContact O-N 3.11Å; V85-L87 VanDerWaalsContact C-N 3.31Å; V85-L87 PolarHBondContact O-N 2.98Å; L87-V89 VanDerWaalsContact C-N 3.29Å; L87-V89 PolarHBondContact O-N 3.03Å; L87-Q90 WeakPolarHBondContact O-CB 3.46Å; L87-Q90 PolarHBondContact O-N 2.93Å; L87-Q90 VanDerWaalsContact O-N 3.1Å; L87-Y91 HydrophobicContact CD1-CD2 4.01Å; L87-Y91 HydrophobicContact CD1-CE2 3.52Å; L87-Y91 HydrophobicContact CD2-CE2 4.2Å; L87-Y91 HydrophobicContact CG-CD2 3.89Å; L87-Y91 HydrophobicContact CG-CE2 3.65Å; L87-Y91 VanDerWaalsContact O-CD2 3.22Å; L87-Y91 WeakPolarHBondContact O-CD2 3.35Å; L87-Y91 PolarHBondContact O-N 3.04Å; L87-I125 HydrophobicContact CD1-CD1 4.29Å; L87-I125 HydrophobicContact CD1-CG2 3.85Å; L87-I125 HydrophobicContact CD2-CB 4.33Å; L87-I125 HydrophobicContact CD2-CG2 3.7Å; L87-I125 HydrophobicContact CG-CG2 4.4Å; L87-L129 HydrophobicContact CD2-CD1 4.34Å; L87-V302 HydrophobicContact CB-CG1 4.3Å; L87-P306 HydrophobicContact CD1-CG 4.04Å
88	F	91.2	Very high	87.8	Confident	108 Å²	108	27.2 Å²	27.2	47%	0.474	14%	0.135	S	C	.	.	H	α-helix	trans	-58.1	-43.7	176.5	177.9	-112.5	0	0	0	111.7	L84 V85 Q90 Y91 I92 L112 L457	L84-F88 WeakPolarHBondContact O-CB 3.4Å; L84-F88 PolarHBondContact O-N 3.36Å; V85-F88 PolarHBondContact O-N 3.37Å; F88-Q90 VanDerWaalsContact C-N 3.33Å; F88-Q90 PolarHBondContact O-N 2.94Å; F88-Y91 PolarHBondContact O-N 3.29Å; F88-I92 HydrophobicContact CD1-CD1 3.64Å; F88-I92 HydrophobicContact CE1-CD1 3.26Å; F88-I92 HydrophobicContact CE1-CG1 4.25Å; F88-I92 HydrophobicContact CE2-CD1 4.29Å; F88-I92 HydrophobicContact CE2-CG1 4.46Å; F88-I92 HydrophobicContact CG-CD1 4.32Å; F88-I92 HydrophobicContact CZ-CD1 3.62Å; F88-I92 HydrophobicContact CZ-CG1 4.17Å; F88-I92 WeakPolarHBondContact O-CG1 3.28Å; F88-I92 PolarHBondContact O-N 3.36Å; F88-L112 HydrophobicContact CE2-CD1 4.35Å; F88-L457 HydrophobicContact CD1-CD1 4.28Å; F88-L457 HydrophobicContact CE1-CD1 4.3Å
89	V	91.1	Very high	86.5	Confident	0 Å²	0	31.7 Å²	31.7	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-60.4	-41.9	174.5	166.2	0	0	0	0	111.8	V85 L87 Y91 I92 N93 L457 I458	V85-V89 HydrophobicContact CG1-CG2 4.45Å; V85-V89 WeakPolarHBondContact O-CB 3.2Å; V85-V89 VanDerWaalsContact O-CG2 3.29Å; V85-V89 WeakPolarHBondContact O-CG2 3.42Å; V85-V89 PolarHBondContact O-N 3.4Å; L87-V89 VanDerWaalsContact C-N 3.29Å; L87-V89 PolarHBondContact O-N 3.03Å; V89-Y91 VanDerWaalsContact C-N 3.33Å; V89-Y91 PolarHBondContact O-N 3.24Å; V89-I92 PolarHBondContact O-N 3Å; V89-N93 PolarHBondContact O-N 3.44Å; V89-N93 PolarHBondContact O-ND2 3.08Å; V89-L457 HydrophobicContact CG2-CB 4Å; V89-L457 HydrophobicContact CG2-CD1 3.97Å; V89-I458 HydrophobicContact CG1-CD1 3.92Å; V89-I458 HydrophobicContact CG1-CG1 4.42Å; V89-I458 HydrophobicContact CG2-CG1 4.27Å
90	Q	91.4	Very high	85.2	Confident	0 Å²	0	38.7 Å²	38.7	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-62.9	-40.9	176.5	-174.3	64.8	-8.3	0	0	111.7	A86 L87 F88 I92 N93 I94 A303 P306 H324	A86-Q90 PolarHBondContact O-N 3.13Å; L87-Q90 WeakPolarHBondContact O-CB 3.46Å; L87-Q90 PolarHBondContact O-N 2.93Å; L87-Q90 VanDerWaalsContact O-N 3.1Å; F88-Q90 VanDerWaalsContact C-N 3.33Å; F88-Q90 PolarHBondContact O-N 2.94Å; Q90-I92 PolarHBondContact O-N 3.41Å; Q90-N93 PolarHBondContact O-N 3.05Å; Q90-I94 HydrophobicContact CG-CD1 3.88Å; Q90-I94 VanDerWaalsContact O-CG1 3.31Å; Q90-I94 WeakPolarHBondContact O-CG1 3.38Å; Q90-I94 PolarHBondContact O-N 3.2Å; Q90-I94 VanDerWaalsContact O-N 3.09Å; Q90-A303 PolarHBondContact NE2-O 2.98Å; Q90-P306 HydrophobicContact CG-CB 4.24Å; Q90-P306 HydrophobicContact CG-CG 4.26Å; Q90-H324 PolarHBondContact OE1-CD2 3.06Å
91	Y	88.6	Confident	83.3	Confident	12 Å²	12	43.9 Å²	43.9	5%	0.047	20%	0.195	C	C	.	.	H	α-helix	trans	-63.3	-38.8	174.4	-81.2	-71	0	0	0	112.7	L87 F88 V89 N93 I94 Y95 M117 A122	L87-Y91 HydrophobicContact CD1-CD2 4.01Å; L87-Y91 HydrophobicContact CD1-CE2 3.52Å; L87-Y91 HydrophobicContact CD2-CE2 4.2Å; L87-Y91 HydrophobicContact CG-CD2 3.89Å; L87-Y91 HydrophobicContact CG-CE2 3.65Å; L87-Y91 VanDerWaalsContact O-CD2 3.22Å; L87-Y91 WeakPolarHBondContact O-CD2 3.35Å; L87-Y91 PolarHBondContact O-N 3.04Å; F88-Y91 PolarHBondContact O-N 3.29Å; V89-Y91 VanDerWaalsContact C-N 3.33Å; V89-Y91 PolarHBondContact O-N 3.24Å; Y91-N93 VanDerWaalsContact C-N 3.34Å; Y91-N93 PolarHBondContact O-N 2.84Å; Y91-I94 PolarHBondContact O-N 3.44Å; Y91-Y95 AromaticContact CD1-CD2 3.69Å; Y91-Y95 HydrophobicContact CD1-CD2 3.69Å; Y91-Y95 AromaticContact CD1-CE2 3.51Å; Y91-Y95 HydrophobicContact CD1-CE2 3.51Å; Y91-Y95 HydrophobicContact CE1-CD2 4.45Å; Y91-Y95 AromaticContact CE1-CE2 3.82Å; Y91-Y95 HydrophobicContact CE1-CE2 3.82Å; Y91-Y95 PolarHBondContact O-N 2.92Å; Y91-M117 HydrophobicContact CD1-CG 3.79Å; Y91-M117 HydrophobicContact CD1-SD 3.72Å; Y91-M117 HydrophobicContact CE1-CG 3.69Å; Y91-M117 HydrophobicContact CE1-SD 4.06Å; Y91-M117 HydrophobicContact CG-SD 4.15Å; Y91-A122 HydrophobicContact CE2-CB 4.2Å; Y91-A122 WeakPolarHBondContact OH-CA 3.31Å; Y91-A122 WeakPolarHBondContact OH-CB 3.38Å
92	I	87.1	Confident	81.4	Confident	7 Å²	7	44.3 Å²	44.3	4%	0.036	20%	0.203	C	C	.	.	H	α-helix	trans	-60.5	-45.4	173.6	-69.4	160.7	0	0	0	111	F88 V89 Q90 I94 R96 L112 L453	F88-I92 HydrophobicContact CD1-CD1 3.64Å; F88-I92 HydrophobicContact CE1-CD1 3.26Å; F88-I92 HydrophobicContact CE1-CG1 4.25Å; F88-I92 HydrophobicContact CE2-CD1 4.29Å; F88-I92 HydrophobicContact CE2-CG1 4.46Å; F88-I92 HydrophobicContact CG-CD1 4.32Å; F88-I92 HydrophobicContact CZ-CD1 3.62Å; F88-I92 HydrophobicContact CZ-CG1 4.17Å; F88-I92 WeakPolarHBondContact O-CG1 3.28Å; F88-I92 PolarHBondContact O-N 3.36Å; V89-I92 PolarHBondContact O-N 3Å; Q90-I92 PolarHBondContact O-N 3.41Å; I92-I94 VanDerWaalsContact C-N 3.3Å; I92-I94 PolarHBondContact O-N 3Å; I92-R96 PolarHBondContact O-N 3.5Å; I92-L112 HydrophobicContact CB-CD2 4.3Å; I92-L112 HydrophobicContact CG1-CD1 4.18Å; I92-L112 HydrophobicContact CG1-CD2 4.03Å; I92-L453 HydrophobicContact CD1-CD2 3.6Å
93	N	85.4	Confident	79.5	Confident	7 Å²	7	53.9 Å²	53.9	4%	0.037	24%	0.24	C	C	.	.	H	α-helix	trans	-65.3	-32.8	-178.2	-71.4	-27.8	0	0	0	112.7	V89 Q90 Y91 W320	V89-N93 PolarHBondContact O-N 3.44Å; V89-N93 PolarHBondContact O-ND2 3.08Å; Q90-N93 PolarHBondContact O-N 3.05Å; Y91-N93 VanDerWaalsContact C-N 3.34Å; Y91-N93 PolarHBondContact O-N 2.84Å; N93-W320 PolarHBondContact ND2-NE1 3.33Å
94	I	85.4	Confident	77.5	Confident	1 Å²	1	58 Å²	58	1%	0.005	27%	0.27	C	S	.	.	H	α-helix	trans	-83.2	-46.8	-179.4	-65.5	168.7	0	0	0	112.3	Q90 Y91 I92 P306 L307 V310 Q314	Q90-I94 HydrophobicContact CG-CD1 3.88Å; Q90-I94 VanDerWaalsContact O-CG1 3.31Å; Q90-I94 WeakPolarHBondContact O-CG1 3.38Å; Q90-I94 PolarHBondContact O-N 3.2Å; Q90-I94 VanDerWaalsContact O-N 3.09Å; Y91-I94 PolarHBondContact O-N 3.44Å; I92-I94 VanDerWaalsContact C-N 3.3Å; I92-I94 PolarHBondContact O-N 3Å; I94-P306 HydrophobicContact CD1-CB 3.78Å; I94-L307 HydrophobicContact CD1-CD2 3.72Å; I94-L307 HydrophobicContact CD1-CG 4.41Å; I94-L307 HydrophobicContact CG1-CD2 3.96Å; I94-V310 HydrophobicContact CD1-CG2 4.2Å; I94-V310 HydrophobicContact CG2-CG1 4.38Å; I94-V310 HydrophobicContact CG2-CG2 3.51Å; I94-Q314 PolarHBondContact O-NE2 3.47Å; I94-Q314 VanDerWaalsContact O-NE2 3.09Å
95	Y	82.2	Confident	75.7	Confident	11 Å²	11	60.8 Å²	60.8	4%	0.043	28%	0.28	C	S	.	.	H	α-helix	trans	-106.4	24.8	-168.7	-61.3	-75.9	0	0	0	114.3	Y91 N113 L116 M117	Y91-Y95 AromaticContact CD1-CD2 3.69Å; Y91-Y95 HydrophobicContact CD1-CD2 3.69Å; Y91-Y95 AromaticContact CD1-CE2 3.51Å; Y91-Y95 HydrophobicContact CD1-CE2 3.51Å; Y91-Y95 HydrophobicContact CE1-CD2 4.45Å; Y91-Y95 AromaticContact CE1-CE2 3.82Å; Y91-Y95 HydrophobicContact CE1-CE2 3.82Å; Y91-Y95 PolarHBondContact O-N 2.92Å; Y95-N113 PolarHBondContact O-N 3.4Å; Y95-N113 VanDerWaalsContact O-N 3.13Å; Y95-L116 HydrophobicContact CD1-CB 3.71Å; Y95-L116 HydrophobicContact CE1-CB 3.68Å; Y95-L116 VanDerWaalsContact CE1-O 3.3Å; Y95-L116 WeakPolarHBondContact CE1-O 3.13Å; Y95-L116 PolarHBondContact OH-O 2.85Å; Y95-M117 HydrophobicContact CE2-CB 4.47Å; Y95-M117 HydrophobicContact CE2-CG 4.3Å
96	R	76.7	Confident	73.8	Confident	58 Å²	58	64.8 Å²	64.8	22%	0.219	31%	0.307	C	S	.	.	B	Isolated β-bridge	trans	-49.2	140.2	179.2	63.4	179.2	-179	-153	0.3	113.6	I92 D317 N450	I92-R96 PolarHBondContact O-N 3.5Å; R96-D317 IonicContact CZ-OD2 2.82Å; R96-D317 IonicContact NH1-OD2 2.73Å; R96-D317 PolarHBondContact NH1-OD2 3.32Å; R96-D317 IonicContact NH2-OD2 3.98Å; R96-D317 PolarHBondContact NH2-OD2 3.44Å; R96-N450 WeakPolarHBondContact CB-ND2 3.48Å; R96-N450 VanDerWaalsContact CD-ND2 3.3Å; R96-N450 WeakPolarHBondContact CD-ND2 3.32Å
97	T	67.6	Low	71.8	Confident	10 Å²	10	67.1 Å²	67.1	6%	0.061	33%	0.327	C	S	.	.			trans	-122.1	159.1	168.6	63.1	0	0	0	0	111.8	W99 T110 S111 N113 W449	T97-W99 VanDerWaalsContact C-N 3.29Å; T97-W99 PolarHBondContact O-N 2.96Å; T97-T110 PolarHBondContact OG1-O 3.08Å; T97-S111 WeakPolarHBondContact OG1-CA 3.42Å; T97-S111 PolarHBondContact OG1-O 3.4Å; T97-N113 HydrophobicContact CG2-CB 4.06Å; T97-N113 WeakPolarHBondContact CG2-ND2 3.42Å; T97-N113 WeakPolarHBondContact CG2-OD1 3.39Å; T97-W449 WeakPolarHBondContact O-CZ2 3.26Å
98	V	64.6	Low	69.8	Low	79 Å²	79	67.6 Å²	67.6	48%	0.479	33%	0.331	S	S	.	.			trans	-89.7	72	172.3	-172.6	0	0	0	0	107.9	W100 Y101	V98-W100 HydrophobicContact CB-CH2 4.3Å; V98-W100 HydrophobicContact CB-CZ2 4.43Å; V98-W100 HydrophobicContact CG1-CD2 3.97Å; V98-W100 HydrophobicContact CG1-CE3 4.35Å; V98-W100 HydrophobicContact CG1-CH2 3.91Å; V98-W100 HydrophobicContact CG1-CZ2 3.58Å; V98-W100 HydrophobicContact CG1-CZ3 4.28Å; V98-W100 HydrophobicContact CG2-CH2 4.38Å; V98-W100 PolarHBondContact O-N 3.4Å; V98-Y101 PolarHBondContact O-N 2.91Å
99	W	62.7	Low	68.1	Low	138 Å²	138	66.7 Å²	66.7	52%	0.523	34%	0.338	S	S	.	.	T	Hydrogen-bonded Turn	trans	-71.3	-10.5	-171.8	69.7	-87	0	0	0	114.5	T97 W449	T97-W99 VanDerWaalsContact C-N 3.29Å; T97-W99 PolarHBondContact O-N 2.96Å; W99-W449 AromaticContact CD1-CH2 3.99Å; W99-W449 AromaticContact CD1-CZ2 3.8Å
100	W	64.2	Low	66.7	Low	150 Å²	150	69.2 Å²	69.2	57%	0.568	35%	0.354	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.3	5	176.2	63.9	90.4	0	0	0	113.7	V98 W449	V98-W100 HydrophobicContact CB-CH2 4.3Å; V98-W100 HydrophobicContact CB-CZ2 4.43Å; V98-W100 HydrophobicContact CG1-CD2 3.97Å; V98-W100 HydrophobicContact CG1-CE3 4.35Å; V98-W100 HydrophobicContact CG1-CH2 3.91Å; V98-W100 HydrophobicContact CG1-CZ2 3.58Å; V98-W100 HydrophobicContact CG1-CZ3 4.28Å; V98-W100 HydrophobicContact CG2-CH2 4.38Å; V98-W100 PolarHBondContact O-N 3.4Å; W100-W449 AromaticContact CH2-CD1 3.19Å; W100-W449 HydrophobicContact CH2-CG 4.32Å; W100-W449 AromaticContact CH2-NE1 3.03Å; W100-W449 AromaticContact CZ3-CD1 3.32Å; W100-W449 HydrophobicContact CZ3-CD2 4.27Å; W100-W449 AromaticContact CZ3-CE2 3.54Å; W100-W449 HydrophobicContact CZ3-CG 4.12Å; W100-W449 HydrophobicContact CZ3-CZ2 4.12Å; W100-W449 AromaticContact CZ3-NE1 2.96Å
101	Y	53.4	Low	65.3	Low	145 Å²	145	72 Å²	72	57%	0.569	37%	0.373	S	S	*	.	S	Bend	trans	-87.8	142.6	176.3	-159.8	-97.8	0	0	0	111	V98	V98-Y101 PolarHBondContact O-N 2.91Å
102	P	52.9	Low	64.4	Low	87 Å²	87	71.9 Å²	71.9	57%	0.565	37%	0.373	S	S	*	.			trans	-59.6	150.2	-173.6	19.5	-31.8	0	0	0	114.5	S104	P102-S104 PolarHBondContact O-N 2.95Å
103	Y	54.3	Low	63.8	Low	208 Å²	208	73.5 Å²	73.5	82%	0.816	38%	0.382	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.6	7.9	-166.9	-90.3	-93.8	0	0	0	119.5	H105	Y103-H105 VanDerWaalsContact C-N 3.26Å; Y103-H105 PolarHBondContact O-N 2.63Å
104	S	52.8	Low	63.4	Low	91 Å²	91	76.9 Å²	76.9	64%	0.636	40%	0.397	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74	-12.1	-174.9	54.8	0	0	0	0	114.6	P102	P102-S104 PolarHBondContact O-N 2.95Å
105	H	55.4	Low	62.7	Low	125 Å²	125	84.9 Å²	84.9	58%	0.579	43%	0.433	S	S	*	.	S	Bend	trans	-119.4	138.5	174.9	-74.7	-72.6	0	0	0	111.9	Y103 A107 A108	Y103-H105 VanDerWaalsContact C-N 3.26Å; Y103-H105 PolarHBondContact O-N 2.63Å; H105-A107 PolarHBondContact O-N 2.97Å; H105-A108 VanDerWaalsContact O-CB 3.31Å; H105-A108 WeakPolarHBondContact O-CB 3.41Å; H105-A108 PolarHBondContact O-N 3.43Å
106	P	55.8	Low	62.4	Low	117 Å²	117	86.7 Å²	86.7	76%	0.76	44%	0.444	S	S	*	.	G	3₁₀ helix	trans	-57.4	-22.2	178.2	2.1	-5.6	0	0	0	113.9	A108 S109	P106-A108 PolarHBondContact O-N 3.44Å; P106-S109 PolarHBondContact O-OG 3.04Å; P106-S109 VanDerWaalsContact O-OG 3.05Å
107	A	50.7	Low	62.6	Low	50 Å²	50	85.5 Å²	85.5	41%	0.413	44%	0.441	S	S	.	.	G	3₁₀ helix	trans	-70.5	-4.1	175.1	0	0	0	0	0	114.9	H105	H105-A107 PolarHBondContact O-N 2.97Å
108	A	51.4	Low	63.4	Low	15 Å²	15	86.4 Å²	86.4	12%	0.124	45%	0.445	C	S	.	.	G	3₁₀ helix	trans	-89.6	-8.5	178.6	0	0	0	0	0	114	H105 P106	H105-A108 VanDerWaalsContact O-CB 3.31Å; H105-A108 WeakPolarHBondContact O-CB 3.41Å; H105-A108 PolarHBondContact O-N 3.43Å; P106-A108 PolarHBondContact O-N 3.44Å
109	S	57.3	Low	64.5	Low	89 Å²	89	88.2 Å²	88.2	62%	0.622	45%	0.445	S	S	*	.	S	Bend	trans	-83	-19.6	-177	60.6	0	0	0	0	114.3	P106	P106-S109 PolarHBondContact O-OG 3.04Å; P106-S109 VanDerWaalsContact O-OG 3.05Å
110	T	60	Low	65.8	Low	53 Å²	53	83.7 Å²	83.7	33%	0.325	43%	0.429	S	S	.	.			trans	-133.9	140.3	-177.7	54.2	0	0	0	0	112.6	T97 L112 F114	T97-T110 PolarHBondContact OG1-O 3.08Å; T110-L112 PolarHBondContact O-N 3.1Å; T110-L112 PolarHBondContact OG1-O 2.98Å; T110-F114 HydrophobicContact CG2-CD2 3.96Å; T110-F114 HydrophobicContact CG2-CE2 4.03Å
111	S	63	Low	67	Low	58 Å²	58	76.6 Å²	76.6	41%	0.406	40%	0.402	S	S	.	.	S	Bend	trans	-68.8	-13.1	-179.3	57.8	0	0	0	0	115.1	T97	T97-S111 WeakPolarHBondContact OG1-CA 3.42Å; T97-S111 PolarHBondContact OG1-O 3.4Å
112	L	70.5	Confident	68.7	Low	11 Å²	11	70.5 Å²	70.5	6%	0.058	38%	0.382	C	S	.	.	B	Isolated β-bridge	trans	-132.3	148.5	174.3	-64.1	174.9	0	0	0	110.3	F88 I92 T110 F114	F88-L112 HydrophobicContact CE2-CD1 4.35Å; I92-L112 HydrophobicContact CB-CD2 4.3Å; I92-L112 HydrophobicContact CG1-CD1 4.18Å; I92-L112 HydrophobicContact CG1-CD2 4.03Å; T110-L112 PolarHBondContact O-N 3.1Å; T110-L112 PolarHBondContact OG1-O 2.98Å; L112-F114 HydrophobicContact CB-CD1 4.35Å; L112-F114 HydrophobicContact CB-CD2 4.48Å; L112-F114 HydrophobicContact CB-CE1 4.06Å; L112-F114 HydrophobicContact CB-CE2 4.21Å; L112-F114 HydrophobicContact CB-CZ 3.98Å; L112-F114 HydrophobicContact CD1-CE1 4.17Å; L112-F114 HydrophobicContact CD1-CZ 4.32Å; L112-F114 VanDerWaalsContact O-CD2 3.3Å; L112-F114 WeakPolarHBondContact O-CD2 3.44Å; L112-F114 PolarHBondContact O-N 3Å
113	N	74.6	Confident	70.5	Confident	40 Å²	40	69.3 Å²	69.3	21%	0.214	37%	0.37	C	S	.	.			trans	-75.6	71.2	172	-80.4	-39.7	0	0	0	110.6	Y95 T97 H115 L116	Y95-N113 PolarHBondContact O-N 3.4Å; Y95-N113 VanDerWaalsContact O-N 3.13Å; T97-N113 HydrophobicContact CG2-CB 4.06Å; T97-N113 WeakPolarHBondContact CG2-ND2 3.42Å; T97-N113 WeakPolarHBondContact CG2-OD1 3.39Å; N113-H115 PolarHBondContact O-N 3.28Å; N113-H115 VanDerWaalsContact O-N 3.07Å; N113-L116 HydrophobicContact CB-CB 4.35Å; N113-L116 HydrophobicContact CB-CD1 4.22Å; N113-L116 PolarHBondContact O-N 3.3Å
114	F	75.2	Confident	72.3	Confident	79 Å²	79	60.2 Å²	60.2	35%	0.346	34%	0.335	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56.2	-26.7	-177.3	-69.7	-64.8	0	0	0	114	T110 L112 L116 M117 Y119	T110-F114 HydrophobicContact CG2-CD2 3.96Å; T110-F114 HydrophobicContact CG2-CE2 4.03Å; L112-F114 HydrophobicContact CB-CD1 4.35Å; L112-F114 HydrophobicContact CB-CD2 4.48Å; L112-F114 HydrophobicContact CB-CE1 4.06Å; L112-F114 HydrophobicContact CB-CE2 4.21Å; L112-F114 HydrophobicContact CB-CZ 3.98Å; L112-F114 HydrophobicContact CD1-CE1 4.17Å; L112-F114 HydrophobicContact CD1-CZ 4.32Å; L112-F114 VanDerWaalsContact O-CD2 3.3Å; L112-F114 WeakPolarHBondContact O-CD2 3.44Å; L112-F114 PolarHBondContact O-N 3Å; F114-L116 VanDerWaalsContact C-N 3.31Å; F114-L116 PolarHBondContact O-N 3.27Å; F114-M117 HydrophobicContact CD1-CE 4.09Å; F114-M117 PolarHBondContact O-N 3.04Å; F114-Y119 WeakPolarHBondContact CB-OH 3.49Å; F114-Y119 PolarHBondContact O-OH 3.35Å; F114-Y119 VanDerWaalsContact O-OH 3.05Å
115	H	71.9	Confident	74.2	Confident	168 Å²	168	55.9 Å²	55.9	78%	0.778	30%	0.304	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71	-23.7	176.5	-173.7	-76.6	0	0	0	113.4	N113	N113-H115 PolarHBondContact O-N 3.28Å; N113-H115 VanDerWaalsContact O-N 3.07Å
116	L	75.9	Confident	75.9	Confident	50 Å²	50	52 Å²	52	26%	0.262	29%	0.289	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.2	-13.1	178.6	-84.6	74.3	0	0	0	112.5	Y95 N113 F114	Y95-L116 HydrophobicContact CD1-CB 3.71Å; Y95-L116 HydrophobicContact CE1-CB 3.68Å; Y95-L116 VanDerWaalsContact CE1-O 3.3Å; Y95-L116 WeakPolarHBondContact CE1-O 3.13Å; Y95-L116 PolarHBondContact OH-O 2.85Å; N113-L116 HydrophobicContact CB-CB 4.35Å; N113-L116 HydrophobicContact CB-CD1 4.22Å; N113-L116 PolarHBondContact O-N 3.3Å; F114-L116 VanDerWaalsContact C-N 3.31Å; F114-L116 PolarHBondContact O-N 3.27Å
117	M	80.1	Confident	77.5	Confident	32 Å²	32	47.3 Å²	47.3	16%	0.158	26%	0.259	C	S	.	.	S	Bend	trans	-82.5	127.7	-178.4	-166.5	176	67.4	0	0	110.3	Y91 Y95 F114 Y119	Y91-M117 HydrophobicContact CD1-CG 3.79Å; Y91-M117 HydrophobicContact CD1-SD 3.72Å; Y91-M117 HydrophobicContact CE1-CG 3.69Å; Y91-M117 HydrophobicContact CE1-SD 4.06Å; Y91-M117 HydrophobicContact CG-SD 4.15Å; Y95-M117 HydrophobicContact CE2-CB 4.47Å; Y95-M117 HydrophobicContact CE2-CG 4.3Å; F114-M117 HydrophobicContact CD1-CE 4.09Å; F114-M117 PolarHBondContact O-N 3.04Å; M117-Y119 HydrophobicContact CE-CD1 3.94Å; M117-Y119 HydrophobicContact CE-CE1 3.57Å; M117-Y119 PolarHBondContact O-N 3.17Å
118	D	85.2	Confident	79.3	Confident	29 Å²	29	45.9 Å²	45.9	16%	0.155	24%	0.244	C	C	.	.			trans	-81.6	105.9	173	-169.9	-24.7	0	0	0	110.2	H120 L121 A122 H181	D118-H120 VanDerWaalsContact C-N 3.28Å; D118-H120 PolarHBondContact O-N 3.46Å; D118-H120 WeakPolarHBondContact OD1-CB 3.49Å; D118-H120 IonicContact OD1-CD2 3.73Å; D118-H120 IonicContact OD1-CG 2.72Å; D118-H120 PolarHBondContact OD1-N 2.67Å; D118-L121 HydrophobicContact CB-CB 3.97Å; D118-L121 PolarHBondContact O-N 2.98Å; D118-L121 PolarHBondContact OD1-N 3.44Å; D118-A122 PolarHBondContact O-N 3.14Å; D118-A122 VanDerWaalsContact O-N 3.1Å; D118-H181 IonicContact OD2-CD2 3.65Å; D118-H181 IonicContact OD2-CE1 3.71Å; D118-H181 IonicContact OD2-NE2 2.72Å; D118-H181 PolarHBondContact OD2-NE2 3.05Å
119	Y	87.5	Confident	81.1	Confident	118 Å²	118	45.8 Å²	45.8	46%	0.463	24%	0.241	S	C	.	.	H	α-helix	trans	-63	-33	178.4	-62.2	-83.1	0	0	0	112.8	F114 M117 A122 I123	F114-Y119 WeakPolarHBondContact CB-OH 3.49Å; F114-Y119 PolarHBondContact O-OH 3.35Å; F114-Y119 VanDerWaalsContact O-OH 3.05Å; M117-Y119 HydrophobicContact CE-CD1 3.94Å; M117-Y119 HydrophobicContact CE-CE1 3.57Å; M117-Y119 PolarHBondContact O-N 3.17Å; Y119-A122 PolarHBondContact O-N 2.93Å; Y119-I123 WeakPolarHBondContact O-CB 3.28Å; Y119-I123 WeakPolarHBondContact O-CD1 3.33Å; Y119-I123 WeakPolarHBondContact O-CG1 3.46Å; Y119-I123 PolarHBondContact O-N 3.37Å
120	H	89.4	Confident	82.6	Confident	42 Å²	42	42.3 Å²	42.3	19%	0.194	22%	0.218	C	C	.	.	H	α-helix	trans	-70.8	-37.2	-179.4	-60.9	-83.4	0	0	0	111	D118 F124 N176	D118-H120 VanDerWaalsContact C-N 3.28Å; D118-H120 PolarHBondContact O-N 3.46Å; D118-H120 WeakPolarHBondContact OD1-CB 3.49Å; D118-H120 IonicContact OD1-CD2 3.73Å; D118-H120 IonicContact OD1-CG 2.72Å; D118-H120 PolarHBondContact OD1-N 2.67Å; H120-F124 WeakPolarHBondContact O-CB 3.25Å; H120-F124 PolarHBondContact O-N 3.46Å; H120-N176 PolarHBondContact CD2-ND2 2.69Å; H120-N176 PolarHBondContact CE1-ND2 2.99Å; H120-N176 PolarHBondContact ND1-ND2 3.39Å; H120-N176 PolarHBondContact NE2-ND2 3.22Å
121	L	89.1	Confident	83.8	Confident	2 Å²	2	41 Å²	41	1%	0.01	21%	0.207	C	C	.	.	H	α-helix	trans	-64.9	-45.9	172.3	-178.3	67.9	0	0	0	111.7	D118 I123 F124 I125 L177 L189 L305 F309	D118-L121 HydrophobicContact CB-CB 3.97Å; D118-L121 PolarHBondContact O-N 2.98Å; D118-L121 PolarHBondContact OD1-N 3.44Å; L121-I123 PolarHBondContact O-N 3.39Å; L121-F124 PolarHBondContact O-N 3.31Å; L121-I125 HydrophobicContact CD1-CD1 4.14Å; L121-I125 HydrophobicContact CD1-CG1 4.39Å; L121-I125 HydrophobicContact CD2-CD1 4.48Å; L121-I125 HydrophobicContact CG-CD1 3.88Å; L121-I125 HydrophobicContact CG-CG1 4.49Å; L121-I125 VanDerWaalsContact O-CG1 3.32Å; L121-I125 WeakPolarHBondContact O-CG1 3.43Å; L121-I125 PolarHBondContact O-N 3.35Å; L121-L177 HydrophobicContact CB-CD1 4.28Å; L121-L177 HydrophobicContact CD1-CD2 4.44Å; L121-L189 HydrophobicContact CD1-CD1 4.36Å; L121-L305 HydrophobicContact CD1-CD2 4.14Å; L121-L305 HydrophobicContact CD1-CG 4.33Å; L121-F309 HydrophobicContact CD1-CD1 4.47Å; L121-F309 HydrophobicContact CD1-CD2 3.98Å; L121-F309 HydrophobicContact CD1-CE2 4.03Å; L121-F309 HydrophobicContact CD1-CG 4.22Å; L121-F309 HydrophobicContact CD1-CZ 4.31Å; L121-F309 HydrophobicContact CD2-CB 3.4Å; L121-F309 HydrophobicContact CD2-CD1 4.12Å; L121-F309 HydrophobicContact CD2-CD2 3.81Å; L121-F309 HydrophobicContact CD2-CG 3.5Å; L121-F309 HydrophobicContact CG-CG 4.46Å
122	A	90.1	Very high	84.8	Confident	16 Å²	16	39.6 Å²	39.6	13%	0.132	19%	0.193	C	C	.	.	H	α-helix	trans	-62.3	-43	179.9	0	0	0	0	0	112	Y91 D118 Y119 T126	Y91-A122 HydrophobicContact CE2-CB 4.2Å; Y91-A122 WeakPolarHBondContact OH-CA 3.31Å; Y91-A122 WeakPolarHBondContact OH-CB 3.38Å; D118-A122 PolarHBondContact O-N 3.14Å; D118-A122 VanDerWaalsContact O-N 3.1Å; Y119-A122 PolarHBondContact O-N 2.93Å; A122-T126 WeakPolarHBondContact O-CB 3.34Å; A122-T126 PolarHBondContact O-N 2.89Å; A122-T126 PolarHBondContact O-OG1 3.21Å
123	I	91.3	Very high	85.5	Confident	62 Å²	62	39.9 Å²	39.9	32%	0.318	19%	0.194	S	C	.	.	H	α-helix	trans	-64.6	-45.4	175.1	-65	164.4	0	0	0	109.9	Y119 L121 I125 T126 V127 V169 T173	Y119-I123 WeakPolarHBondContact O-CB 3.28Å; Y119-I123 WeakPolarHBondContact O-CD1 3.33Å; Y119-I123 WeakPolarHBondContact O-CG1 3.46Å; Y119-I123 PolarHBondContact O-N 3.37Å; L121-I123 PolarHBondContact O-N 3.39Å; I123-I125 PolarHBondContact O-N 3.13Å; I123-T126 PolarHBondContact O-N 3.39Å; I123-V127 HydrophobicContact CG2-CG2 4.26Å; I123-V127 VanDerWaalsContact O-CG2 3.32Å; I123-V127 WeakPolarHBondContact O-CG2 3.47Å; I123-V127 PolarHBondContact O-N 3.25Å; I123-V169 HydrophobicContact CG2-CG1 3.58Å; I123-T173 HydrophobicContact CB-CG2 3.91Å; I123-T173 HydrophobicContact CG2-CG2 3.64Å
124	F	91.6	Very high	86	Confident	17 Å²	17	39 Å²	39	8%	0.075	19%	0.191	C	C	.	.	H	α-helix	trans	-56.5	-50.5	177.1	175.6	-93.8	0	0	0	111.6	H120 L121 T126 V127 M128 L170 L189 Y301	H120-F124 WeakPolarHBondContact O-CB 3.25Å; H120-F124 PolarHBondContact O-N 3.46Å; L121-F124 PolarHBondContact O-N 3.31Å; F124-T126 VanDerWaalsContact C-N 3.34Å; F124-T126 PolarHBondContact O-N 3.01Å; F124-V127 PolarHBondContact O-N 3.47Å; F124-M128 HydrophobicContact CD1-CG 4.2Å; F124-M128 HydrophobicContact CE1-CG 3.73Å; F124-M128 HydrophobicContact CE2-CG 4.1Å; F124-M128 HydrophobicContact CE2-SD 4.33Å; F124-M128 HydrophobicContact CZ-CG 3.67Å; F124-M128 HydrophobicContact CZ-SD 4.08Å; F124-M128 WeakPolarHBondContact O-CB 3.43Å; F124-M128 VanDerWaalsContact O-CG 3.28Å; F124-M128 WeakPolarHBondContact O-CG 3.43Å; F124-M128 PolarHBondContact O-N 3.48Å; F124-L170 HydrophobicContact CD2-CD2 3.9Å; F124-L170 HydrophobicContact CE2-CD2 4Å; F124-L189 HydrophobicContact CD1-CD2 3.78Å; F124-L189 HydrophobicContact CD1-CG 4.17Å; F124-L189 HydrophobicContact CD2-CD2 4.29Å; F124-L189 HydrophobicContact CE1-CD2 3.35Å; F124-L189 HydrophobicContact CE1-CG 3.56Å; F124-L189 HydrophobicContact CE2-CD2 3.9Å; F124-L189 HydrophobicContact CG-CD2 4.24Å; F124-L189 HydrophobicContact CZ-CD2 3.43Å; F124-L189 VanDerWaalsContact CZ-CD2 3.43Å; F124-L189 HydrophobicContact CZ-CG 3.97Å; F124-Y301 HydrophobicContact CE1-CD1 4.46Å; F124-Y301 AromaticContact CE1-CE1 3.93Å; F124-Y301 HydrophobicContact CE1-CE1 3.93Å
125	I	91.7	Very high	86.3	Confident	0 Å²	0	39 Å²	39	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-58.5	-48	177	-68	166.6	0	0	0	110.2	L87 L121 I123 V127 M128 L129 Y301 L305 P306	L87-I125 HydrophobicContact CD1-CD1 4.29Å; L87-I125 HydrophobicContact CD1-CG2 3.85Å; L87-I125 HydrophobicContact CD2-CB 4.33Å; L87-I125 HydrophobicContact CD2-CG2 3.7Å; L87-I125 HydrophobicContact CG-CG2 4.4Å; L121-I125 HydrophobicContact CD1-CD1 4.14Å; L121-I125 HydrophobicContact CD1-CG1 4.39Å; L121-I125 HydrophobicContact CD2-CD1 4.48Å; L121-I125 HydrophobicContact CG-CD1 3.88Å; L121-I125 HydrophobicContact CG-CG1 4.49Å; L121-I125 VanDerWaalsContact O-CG1 3.32Å; L121-I125 WeakPolarHBondContact O-CG1 3.43Å; L121-I125 PolarHBondContact O-N 3.35Å; I123-I125 PolarHBondContact O-N 3.13Å; I125-V127 VanDerWaalsContact C-N 3.32Å; I125-V127 PolarHBondContact O-N 2.85Å; I125-M128 WeakPolarHBondContact O-CB 3.16Å; I125-M128 PolarHBondContact O-N 2.92Å; I125-M128 VanDerWaalsContact O-N 3.14Å; I125-L129 HydrophobicContact CG2-CD1 3.74Å; I125-L129 HydrophobicContact CG2-CG 4.15Å; I125-L129 VanDerWaalsContact O-CG 3.26Å; I125-L129 WeakPolarHBondContact O-CG 3.37Å; I125-L129 PolarHBondContact O-N 2.95Å; I125-Y301 WeakPolarHBondContact CG2-O 3.35Å; I125-L305 HydrophobicContact CD1-CD2 4.11Å; I125-L305 HydrophobicContact CD1-CG 4.49Å; I125-L305 HydrophobicContact CG1-CD2 3.87Å; I125-P306 HydrophobicContact CD1-CG 4Å
126	T	91.4	Very high	86.6	Confident	43 Å²	43	31 Å²	31	26%	0.264	15%	0.151	S	C	.	.	H	α-helix	trans	-59.5	-42.9	-178.5	-56.9	0	0	0	0	111.8	F80 L84 A122 I123 F124 L129 A130	F80-T126 HydrophobicContact CE2-CG2 4.46Å; F80-T126 HydrophobicContact CZ-CG2 4.18Å; L84-T126 HydrophobicContact CD1-CG2 4.19Å; A122-T126 WeakPolarHBondContact O-CB 3.34Å; A122-T126 PolarHBondContact O-N 2.89Å; A122-T126 PolarHBondContact O-OG1 3.21Å; I123-T126 PolarHBondContact O-N 3.39Å; F124-T126 VanDerWaalsContact C-N 3.34Å; F124-T126 PolarHBondContact O-N 3.01Å; T126-L129 PolarHBondContact O-N 3.38Å; T126-A130 WeakPolarHBondContact O-CB 3.2Å; T126-A130 PolarHBondContact O-N 2.86Å
127	V	90.5	Very high	86.9	Confident	20 Å²	20	31.3 Å²	31.3	12%	0.121	15%	0.153	C	C	.	.	H	α-helix	trans	-68.9	-37.5	177.7	-177.2	0	0	0	0	111.4	I123 F124 I125 L129 A130 R131 C166 V169 L170	I123-V127 HydrophobicContact CG2-CG2 4.26Å; I123-V127 VanDerWaalsContact O-CG2 3.32Å; I123-V127 WeakPolarHBondContact O-CG2 3.47Å; I123-V127 PolarHBondContact O-N 3.25Å; F124-V127 PolarHBondContact O-N 3.47Å; I125-V127 VanDerWaalsContact C-N 3.32Å; I125-V127 PolarHBondContact O-N 2.85Å; V127-L129 VanDerWaalsContact C-N 3.33Å; V127-L129 PolarHBondContact O-N 3Å; V127-A130 PolarHBondContact O-N 3.47Å; V127-R131 PolarHBondContact O-N 3.34Å; V127-R131 VanDerWaalsContact O-N 3.15Å; V127-C166 WeakPolarHBondContact CG1-SG 3.38Å; V127-V169 HydrophobicContact CG2-CG1 3.88Å; V127-L170 HydrophobicContact CB-CD2 3.74Å; V127-L170 HydrophobicContact CB-CG 4.15Å; V127-L170 HydrophobicContact CG1-CD1 3.9Å; V127-L170 HydrophobicContact CG1-CD2 3.59Å; V127-L170 HydrophobicContact CG1-CG 3.46Å; V127-L170 VanDerWaalsContact CG1-CG 3.46Å
128	M	87.8	Confident	86.9	Confident	20 Å²	20	30 Å²	30	10%	0.099	15%	0.147	C	C	.	.	H	α-helix	trans	-63.5	-36.7	173.5	-70.9	-58.1	-63.7	0	0	112.6	F124 I125 R131 L170 F193 F297	F124-M128 HydrophobicContact CD1-CG 4.2Å; F124-M128 HydrophobicContact CE1-CG 3.73Å; F124-M128 HydrophobicContact CE2-CG 4.1Å; F124-M128 HydrophobicContact CE2-SD 4.33Å; F124-M128 HydrophobicContact CZ-CG 3.67Å; F124-M128 HydrophobicContact CZ-SD 4.08Å; F124-M128 WeakPolarHBondContact O-CB 3.43Å; F124-M128 VanDerWaalsContact O-CG 3.28Å; F124-M128 WeakPolarHBondContact O-CG 3.43Å; F124-M128 PolarHBondContact O-N 3.48Å; I125-M128 WeakPolarHBondContact O-CB 3.16Å; I125-M128 PolarHBondContact O-N 2.92Å; I125-M128 VanDerWaalsContact O-N 3.14Å; M128-R131 WeakPolarHBondContact O-CB 3.19Å; M128-R131 WeakPolarHBondContact O-CD 3.3Å; M128-R131 WeakPolarHBondContact O-CG 3.29Å; M128-L170 HydrophobicContact CG-CD2 4.13Å; M128-L170 HydrophobicContact SD-CD1 4.47Å; M128-L170 HydrophobicContact SD-CD2 3.86Å; M128-F193 HydrophobicContact CE-CE2 3.92Å; M128-F193 HydrophobicContact CE-CZ 3.69Å; M128-F297 HydrophobicContact CE-CZ 3.75Å
129	L	89	Confident	86.3	Confident	12 Å²	12	30 Å²	30	6%	0.063	15%	0.149	C	C	.	.	H	α-helix	trans	-72.4	-37.6	174.7	-61.9	170.7	0	0	0	111.5	F80 L83 L87 I125 T126 V127 R131 V302	F80-L129 HydrophobicContact CD2-CB 4.2Å; F80-L129 HydrophobicContact CE2-CB 4.14Å; L83-L129 HydrophobicContact CB-CD1 4.16Å; L83-L129 HydrophobicContact CB-CD2 4.35Å; L83-L129 HydrophobicContact CD1-CD2 4.09Å; L87-L129 HydrophobicContact CD2-CD1 4.34Å; I125-L129 HydrophobicContact CG2-CD1 3.74Å; I125-L129 HydrophobicContact CG2-CG 4.15Å; I125-L129 VanDerWaalsContact O-CG 3.26Å; I125-L129 WeakPolarHBondContact O-CG 3.37Å; I125-L129 PolarHBondContact O-N 2.95Å; T126-L129 PolarHBondContact O-N 3.38Å; V127-L129 VanDerWaalsContact C-N 3.33Å; V127-L129 PolarHBondContact O-N 3Å; L129-R131 PolarHBondContact O-N 3Å; L129-V302 HydrophobicContact CD1-CG2 3.75Å; L129-V302 HydrophobicContact CD2-CG2 3.83Å; L129-V302 HydrophobicContact CG-CG2 4.45Å
130	A	88.3	Confident	85.7	Confident	16 Å²	16	27.9 Å²	27.9	13%	0.132	14%	0.143	C	C	.	.	H	α-helix	trans	-68.7	-15.5	178.4	0	0	0	0	0	113.4	F80 T126 V127 R132 L133 V134	F80-A130 HydrophobicContact CD2-CB 4.21Å; F80-A130 HydrophobicContact CE2-CB 3.62Å; F80-A130 HydrophobicContact CZ-CB 4.04Å; T126-A130 WeakPolarHBondContact O-CB 3.2Å; T126-A130 PolarHBondContact O-N 2.86Å; V127-A130 PolarHBondContact O-N 3.47Å; A130-R132 PolarHBondContact O-N 3.29Å; A130-R132 VanDerWaalsContact O-N 3.13Å; A130-L133 WeakPolarHBondContact O-CB 3.21Å; A130-L133 PolarHBondContact O-N 3.48Å; A130-L133 VanDerWaalsContact O-N 3.11Å; A130-V134 HydrophobicContact CB-CG2 4.46Å; A130-V134 WeakPolarHBondContact O-CG2 2.96Å; A130-V134 PolarHBondContact O-N 2.94Å
131	R	86.1	Confident	84.6	Confident	25 Å²	25	28.2 Å²	28.2	9%	0.094	15%	0.148	C	C	.	.	H	α-helix	trans	-50.8	-41.6	-175	80.7	-175.5	-172.7	178.3	-1.1	113.7	V127 M128 L129 W135 F250 F297	V127-R131 PolarHBondContact O-N 3.34Å; V127-R131 VanDerWaalsContact O-N 3.15Å; M128-R131 WeakPolarHBondContact O-CB 3.19Å; M128-R131 WeakPolarHBondContact O-CD 3.3Å; M128-R131 WeakPolarHBondContact O-CG 3.29Å; L129-R131 PolarHBondContact O-N 3Å; R131-W135 WeakPolarHBondContact O-CB 3.16Å; R131-W135 PolarHBondContact O-N 3.11Å; R131-F250 HydrophobicContact CB-CE1 4.08Å; R131-F250 HydrophobicContact CG-CE1 3.87Å; R131-F297 VanDerWaalsContact CZ-CE1 3.43Å; R131-F297 VanDerWaalsContact CZ-CZ 3.43Å; R131-F297 VanDerWaalsContact NH1-CE2 3.3Å
132	R	83.1	Confident	83.6	Confident	29 Å²	29	31.5 Å²	31.5	11%	0.109	17%	0.171	C	C	.	.	H	α-helix	trans	-72.1	-45.3	-178.5	-74.5	178.2	57.1	169.5	3.9	111.2	E76 A130 V134 W135 T136 L336	E76-R132 IonicContact OE1-CZ 3.61Å; E76-R132 IonicContact OE1-NE 3.63Å; E76-R132 IonicContact OE1-NH2 3.03Å; E76-R132 PolarHBondContact OE1-NH2 2.85Å; E76-R132 WeakPolarHBondContact OE2-CB 3.46Å; E76-R132 IonicContact OE2-CZ 2.72Å; E76-R132 IonicContact OE2-NE 2.74Å; E76-R132 PolarHBondContact OE2-NE 2.86Å; E76-R132 VanDerWaalsContact OE2-NE 3.07Å; E76-R132 IonicContact OE2-NH2 4Å; E76-R132 PolarHBondContact OE2-NH2 3.19Å; A130-R132 PolarHBondContact O-N 3.29Å; A130-R132 VanDerWaalsContact O-N 3.13Å; R132-V134 VanDerWaalsContact C-N 3.35Å; R132-V134 PolarHBondContact O-N 3.13Å; R132-W135 PolarHBondContact O-N 2.91Å; R132-T136 PolarHBondContact O-N 3.49Å; R132-T136 PolarHBondContact O-OG1 2.92Å; R132-L336 VanDerWaalsContact CZ-CD2 3.47Å
133	L	85.3	Confident	82.4	Confident	18 Å²	18	38.4 Å²	38.4	9%	0.094	20%	0.2	C	C	.	.	H	α-helix	trans	-58.5	-47	174.4	179.6	63.2	0	0	0	111.3	F73 E76 F77 F80 A130 W135 T136 I137	F73-L133 HydrophobicContact CD2-CD1 4.14Å; F73-L133 HydrophobicContact CE2-CD1 3.83Å; E76-L133 HydrophobicContact CB-CD1 4.2Å; F77-L133 HydrophobicContact CB-CD1 4.09Å; F77-L133 HydrophobicContact CD2-CD2 4.41Å; F80-L133 HydrophobicContact CB-CD2 4.14Å; F80-L133 HydrophobicContact CD1-CD2 3.73Å; F80-L133 HydrophobicContact CE1-CD2 4.37Å; F80-L133 HydrophobicContact CG-CD2 3.97Å; A130-L133 WeakPolarHBondContact O-CB 3.21Å; A130-L133 PolarHBondContact O-N 3.48Å; A130-L133 VanDerWaalsContact O-N 3.11Å; L133-W135 VanDerWaalsContact C-N 3.32Å; L133-W135 PolarHBondContact O-N 3.43Å; L133-T136 PolarHBondContact O-N 3.46Å; L133-I137 HydrophobicContact CD1-CD1 4.28Å; L133-I137 HydrophobicContact CG-CD1 4Å; L133-I137 VanDerWaalsContact O-CG1 3.24Å; L133-I137 WeakPolarHBondContact O-CG1 3.35Å; L133-I137 PolarHBondContact O-N 2.82Å
134	V	85.3	Confident	81	Confident	22 Å²	22	40 Å²	40	13%	0.133	22%	0.217	C	C	.	.	H	α-helix	trans	-59.4	-44.4	176.4	172.3	0	0	0	0	110.4	A130 R132 I137 V138 L162	A130-V134 HydrophobicContact CB-CG2 4.46Å; A130-V134 WeakPolarHBondContact O-CG2 2.96Å; A130-V134 PolarHBondContact O-N 2.94Å; R132-V134 VanDerWaalsContact C-N 3.35Å; R132-V134 PolarHBondContact O-N 3.13Å; V134-I137 PolarHBondContact O-N 2.85Å; V134-V138 HydrophobicContact CG1-CG2 4.46Å; V134-V138 WeakPolarHBondContact O-CB 3.18Å; V134-V138 WeakPolarHBondContact O-CG2 3.37Å; V134-V138 PolarHBondContact O-N 3.19Å; V134-L162 HydrophobicContact CG1-CD2 4Å; V134-L162 HydrophobicContact CG1-CG 4.16Å
135	W	81.5	Confident	79.4	Confident	77 Å²	77	42 Å²	42	29%	0.292	23%	0.233	S	C	.	.	H	α-helix	trans	-63.5	-43.4	177.6	-174.7	-89.2	0	0	0	112.8	R131 R132 L133 V138 S139 F250	R131-W135 WeakPolarHBondContact O-CB 3.16Å; R131-W135 PolarHBondContact O-N 3.11Å; R132-W135 PolarHBondContact O-N 2.91Å; L133-W135 VanDerWaalsContact C-N 3.32Å; L133-W135 PolarHBondContact O-N 3.43Å; W135-V138 CarbonylContact O-C 3.55Å; W135-V138 WeakPolarHBondContact O-CA 3.49Å; W135-V138 WeakPolarHBondContact O-CB 3.43Å; W135-V138 PolarHBondContact O-N 3.49Å; W135-V138 VanDerWaalsContact O-N 3.13Å; W135-S139 PolarHBondContact O-N 3.18Å; W135-S139 PolarHBondContact O-OG 3.46Å; W135-F250 HydrophobicContact CB-CD1 4.42Å; W135-F250 HydrophobicContact CD2-CB 3.75Å; W135-F250 HydrophobicContact CD2-CG 4.45Å; W135-F250 HydrophobicContact CE3-CB 4.12Å; W135-F250 HydrophobicContact CE3-CG 4.43Å; W135-F250 HydrophobicContact CG-CB 3.99Å; W135-F250 HydrophobicContact CZ2-CB 4.3Å; W135-F250 PolarHBondContact NE1-O 3.3Å
136	T	79.4	Confident	77.9	Confident	1 Å²	1	45.9 Å²	45.9	1%	0.006	27%	0.273	C	S	.	.	H	α-helix	trans	-64.8	-40.4	177.7	-59.4	0	0	0	0	112.2	F73 E76 R132 L133 V138 S139 E140	F73-T136 HydrophobicContact CB-CG2 4.46Å; E76-T136 HydrophobicContact CG-CG2 4.28Å; R132-T136 PolarHBondContact O-N 3.49Å; R132-T136 PolarHBondContact O-OG1 2.92Å; L133-T136 PolarHBondContact O-N 3.46Å; T136-V138 VanDerWaalsContact C-N 3.25Å; T136-V138 PolarHBondContact O-N 2.93Å; T136-S139 WeakPolarHBondContact CA-OG 3.28Å; T136-S139 PolarHBondContact O-N 2.86Å; T136-S139 PolarHBondContact O-OG 3.5Å; T136-S139 VanDerWaalsContact O-OG 3.06Å; T136-E140 HydrophobicContact CG2-CG 4.12Å; T136-E140 WeakPolarHBondContact O-CB 3.39Å; T136-E140 VanDerWaalsContact O-CG 3.3Å; T136-E140 WeakPolarHBondContact O-CG 3.47Å; T136-E140 PolarHBondContact O-N 2.87Å
137	I	81.6	Confident	76.7	Confident	57 Å²	57	45.9 Å²	45.9	29%	0.292	28%	0.282	S	S	.	.	H	α-helix	trans	-57.6	-44.9	171.5	-69.2	163.8	0	0	0	110	F73 L133 V134 V141 L162	F73-I137 HydrophobicContact CD2-CG1 3.8Å; F73-I137 HydrophobicContact CE2-CD1 3.94Å; F73-I137 HydrophobicContact CE2-CG1 3.49Å; F73-I137 VanDerWaalsContact CE2-CG1 3.49Å; L133-I137 HydrophobicContact CD1-CD1 4.28Å; L133-I137 HydrophobicContact CG-CD1 4Å; L133-I137 VanDerWaalsContact O-CG1 3.24Å; L133-I137 WeakPolarHBondContact O-CG1 3.35Å; L133-I137 PolarHBondContact O-N 2.82Å; V134-I137 PolarHBondContact O-N 2.85Å; I137-V141 WeakPolarHBondContact O-CB 3.46Å; I137-V141 WeakPolarHBondContact O-CG2 3.16Å; I137-V141 PolarHBondContact O-N 2.89Å; I137-L162 HydrophobicContact CG2-CD2 4.34Å
138	V	79	Confident	76.1	Confident	5 Å²	5	48.2 Å²	48.2	3%	0.03	30%	0.299	C	S	.	.	H	α-helix	trans	-67.4	-35.7	-179.1	166.3	0	0	0	0	112.5	V134 W135 T136 R159 L163	V134-V138 HydrophobicContact CG1-CG2 4.46Å; V134-V138 WeakPolarHBondContact O-CB 3.18Å; V134-V138 WeakPolarHBondContact O-CG2 3.37Å; V134-V138 PolarHBondContact O-N 3.19Å; W135-V138 CarbonylContact O-C 3.55Å; W135-V138 WeakPolarHBondContact O-CA 3.49Å; W135-V138 WeakPolarHBondContact O-CB 3.43Å; W135-V138 PolarHBondContact O-N 3.49Å; W135-V138 VanDerWaalsContact O-N 3.13Å; T136-V138 VanDerWaalsContact C-N 3.25Å; T136-V138 PolarHBondContact O-N 2.93Å; V138-R159 HydrophobicContact CG1-CG 3.88Å; V138-R159 HydrophobicContact CG2-CG 4.03Å; V138-L163 HydrophobicContact CG1-CD1 4.27Å; V138-L163 HydrophobicContact CG2-CD1 4.07Å
139	S	73.4	Confident	75.6	Confident	28 Å²	28	54 Å²	54	20%	0.196	33%	0.329	C	S	.	.	H	α-helix	trans	-79.6	-43.3	-178	65.1	0	0	0	0	113	W135 T136 V141 S142 Q143	W135-S139 PolarHBondContact O-N 3.18Å; W135-S139 PolarHBondContact O-OG 3.46Å; T136-S139 WeakPolarHBondContact CA-OG 3.28Å; T136-S139 PolarHBondContact O-N 2.86Å; T136-S139 PolarHBondContact O-OG 3.5Å; T136-S139 VanDerWaalsContact O-OG 3.06Å; S139-V141 VanDerWaalsContact C-N 3.35Å; S139-V141 PolarHBondContact O-N 3.1Å; S139-S142 VanDerWaalsContact O-CB 3.27Å; S139-S142 WeakPolarHBondContact O-CB 3.37Å; S139-S142 PolarHBondContact O-N 3.12Å; S139-S142 VanDerWaalsContact O-N 3.09Å; S139-Q143 PolarHBondContact O-N 3.24Å
140	E	74.3	Confident	75.1	Confident	74 Å²	74	59.8 Å²	59.8	35%	0.346	36%	0.36	S	S	.	.	H	α-helix	trans	-61.4	-43	177.9	-74.4	-74.5	178.1	0	0	111.4	S72 T136 S142 Q143 S144	S72-E140 WeakPolarHBondContact CB-OE1 3.3Å; T136-E140 HydrophobicContact CG2-CG 4.12Å; T136-E140 WeakPolarHBondContact O-CB 3.39Å; T136-E140 VanDerWaalsContact O-CG 3.3Å; T136-E140 WeakPolarHBondContact O-CG 3.47Å; T136-E140 PolarHBondContact O-N 2.87Å; E140-S142 PolarHBondContact O-N 2.95Å; E140-Q143 PolarHBondContact O-N 2.84Å; E140-Q143 VanDerWaalsContact O-N 3.12Å; E140-S144 PolarHBondContact O-N 3.36Å
141	V	66.9	Low	74.6	Confident	49 Å²	49	67.6 Å²	67.6	30%	0.297	39%	0.386	S	S	.	.	H	α-helix	trans	-62.8	-29.1	176.1	171.6	0	0	0	0	111.9	I137 S139 Q143 L155	I137-V141 WeakPolarHBondContact O-CB 3.46Å; I137-V141 WeakPolarHBondContact O-CG2 3.16Å; I137-V141 PolarHBondContact O-N 2.89Å; S139-V141 VanDerWaalsContact C-N 3.35Å; S139-V141 PolarHBondContact O-N 3.1Å; V141-Q143 VanDerWaalsContact C-N 3.34Å; V141-L155 HydrophobicContact CG1-CB 3.82Å; V141-L155 HydrophobicContact CG1-CD1 4.08Å; V141-L155 HydrophobicContact CG1-CD2 3.83Å; V141-L155 HydrophobicContact CG1-CG 4.11Å
142	S	67.2	Low	74.3	Confident	70 Å²	70	71.8 Å²	71.8	49%	0.49	40%	0.403	S	S	.	.	H	α-helix	trans	-72.1	-26.9	177.8	-157.5	0	0	0	0	113	S139 E140	S139-S142 VanDerWaalsContact O-CB 3.27Å; S139-S142 WeakPolarHBondContact O-CB 3.37Å; S139-S142 PolarHBondContact O-N 3.12Å; S139-S142 VanDerWaalsContact O-N 3.09Å; E140-S142 PolarHBondContact O-N 2.95Å
143	Q	65.5	Low	74.3	Confident	161 Å²	161	74.9 Å²	74.9	75%	0.752	42%	0.42	S	S	*	.	H	α-helix	trans	-88.1	-28.8	-179.9	-63.5	-176.3	33.5	0	0	112.3	S139 E140 V141 S145	S139-Q143 PolarHBondContact O-N 3.24Å; E140-Q143 PolarHBondContact O-N 2.84Å; E140-Q143 VanDerWaalsContact O-N 3.12Å; V141-Q143 VanDerWaalsContact C-N 3.34Å; Q143-S145 PolarHBondContact O-N 3.29Å; Q143-S145 VanDerWaalsContact O-N 3.1Å
144	S	62.7	Low	74.1	Confident	96 Å²	96	78.4 Å²	78.4	67%	0.671	44%	0.442	S	S	*	.			trans	-75.9	12.1	179.3	-175.2	0	0	0	0	114.7	E140 G146	E140-S144 PolarHBondContact O-N 3.36Å; S144-G146 VanDerWaalsContact C-N 3.26Å; S144-G146 PolarHBondContact O-N 3.21Å
145	S	57.3	Low	73.9	Confident	58 Å²	58	80.7 Å²	80.7	41%	0.406	45%	0.453	S	S	.	.			trans	-81.1	56.9	-169.7	-175.6	0	0	0	0	114.3	Q143 Y152	Q143-S145 PolarHBondContact O-N 3.29Å; Q143-S145 VanDerWaalsContact O-N 3.1Å; S145-Y152 WeakPolarHBondContact OG-CD2 3.23Å; S145-Y152 WeakPolarHBondContact OG-CE2 3.43Å
146	G	60	Low	73.9	Confident	83 Å²	83	80.7 Å²	80.7	86%	0.856	46%	0.458	S	S	*	.			trans	-102.4	11.9	173.2	0	0	0	0	0	115.2	S144	S144-G146 VanDerWaalsContact C-N 3.26Å; S144-G146 PolarHBondContact O-N 3.21Å
147	G	66.6	Low	74.2	Confident	42 Å²	42	84.7 Å²	84.7	43%	0.433	48%	0.483	S	S	.	.	S	Bend	trans	-104.3	169.9	-172.9	0	0	0	0	0	115.6
148	S	77.4	Confident	74.2	Confident	70 Å²	70	84.3 Å²	84.3	49%	0.49	49%	0.488	S	S	.	.			trans	-44.9	139.7	174.9	59.8	0	0	0	0	113.2	L150 R151 Y152	S148-L150 PolarHBondContact O-N 3.33Å; S148-R151 WeakPolarHBondContact O-CB 3.32Å; S148-R151 PolarHBondContact O-N 3.08Å; S148-Y152 PolarHBondContact O-N 2.9Å
149	L	78.3	Confident	74.3	Confident	140 Å²	140	88.4 Å²	88.4	73%	0.733	50%	0.503	S	S	*	.	H	α-helix	trans	-42.1	-38.6	-179.5	-84.5	164.3	0	0	0	114.9	Y152 I153	L149-Y152 WeakPolarHBondContact O-CB 3.32Å; L149-Y152 PolarHBondContact O-N 3.01Å; L149-I153 WeakPolarHBondContact O-CG1 3.29Å; L149-I153 PolarHBondContact O-N 3.26Å
150	L	78.6	Confident	74.7	Confident	134 Å²	134	92.6 Å²	92.6	70%	0.702	52%	0.523	S	S	*	.	H	α-helix	trans	-60.6	-44.2	176.6	-106.3	160.7	0	0	0	113.2	S148 Y152 I153 V154	S148-L150 PolarHBondContact O-N 3.33Å; L150-Y152 VanDerWaalsContact C-N 3.33Å; L150-I153 PolarHBondContact O-N 3.14Å; L150-V154 VanDerWaalsContact O-CG2 3.27Å; L150-V154 WeakPolarHBondContact O-CG2 3.41Å; L150-V154 PolarHBondContact O-N 3.38Å
151	R	77.2	Confident	75.4	Confident	180 Å²	180	91.8 Å²	91.8	68%	0.679	53%	0.525	S	S	*	.	H	α-helix	trans	-65.9	-39	176.8	-68.5	180	-178.3	-177.9	0.9	110.9	S148 V154 L155	S148-R151 WeakPolarHBondContact O-CB 3.32Å; S148-R151 PolarHBondContact O-N 3.08Å; R151-V154 PolarHBondContact O-N 3.22Å; R151-L155 WeakPolarHBondContact O-CB 3.4Å; R151-L155 WeakPolarHBondContact O-CG 3.46Å; R151-L155 PolarHBondContact O-N 2.96Å
152	Y	79.9	Confident	76.3	Confident	114 Å²	114	92.7 Å²	92.7	45%	0.447	53%	0.528	S	S	.	.	H	α-helix	trans	-62.4	-46.4	175.8	177.1	-107.1	0	0	0	112.2	S145 S148 L149 L150 L155 I156	S145-Y152 WeakPolarHBondContact OG-CD2 3.23Å; S145-Y152 WeakPolarHBondContact OG-CE2 3.43Å; S148-Y152 PolarHBondContact O-N 2.9Å; L149-Y152 WeakPolarHBondContact O-CB 3.32Å; L149-Y152 PolarHBondContact O-N 3.01Å; L150-Y152 VanDerWaalsContact C-N 3.33Å; Y152-L155 PolarHBondContact O-N 3.5Å; Y152-I156 PolarHBondContact O-N 2.87Å
153	I	82.4	Confident	77.2	Confident	93 Å²	93	92.7 Å²	92.7	48%	0.477	52%	0.522	S	S	.	.	H	α-helix	trans	-62.8	-45.8	176.9	-66.6	166.7	0	0	0	110.5	L149 L150 L155 I156 T157	L149-I153 WeakPolarHBondContact O-CG1 3.29Å; L149-I153 PolarHBondContact O-N 3.26Å; L150-I153 PolarHBondContact O-N 3.14Å; I153-L155 VanDerWaalsContact C-N 3.33Å; I153-L155 PolarHBondContact O-N 3.3Å; I153-I156 WeakPolarHBondContact O-CG2 3.17Å; I153-I156 PolarHBondContact O-N 3.44Å; I153-T157 WeakPolarHBondContact O-CB 3.4Å; I153-T157 PolarHBondContact O-N 2.86Å; I153-T157 PolarHBondContact O-OG1 3.41Å
154	V	82.5	Confident	78.2	Confident	92 Å²	92	88.7 Å²	88.7	56%	0.558	51%	0.509	S	S	*	.	H	α-helix	trans	-60.1	-43.1	177.8	170.8	0	0	0	0	111.7	L150 R151 A158	L150-V154 VanDerWaalsContact O-CG2 3.27Å; L150-V154 WeakPolarHBondContact O-CG2 3.41Å; L150-V154 PolarHBondContact O-N 3.38Å; R151-V154 PolarHBondContact O-N 3.22Å; V154-A158 VanDerWaalsContact O-CB 3.29Å; V154-A158 WeakPolarHBondContact O-CB 3.17Å; V154-A158 PolarHBondContact O-N 2.65Å
155	L	80.1	Confident	79.5	Confident	71 Å²	71	89.9 Å²	89.9	37%	0.372	51%	0.505	S	S	.	.	H	α-helix	trans	-67.1	-39.1	179.1	-71.5	170.5	0	0	0	112.6	V141 R151 Y152 I153 A158 R159	V141-L155 HydrophobicContact CG1-CB 3.82Å; V141-L155 HydrophobicContact CG1-CD1 4.08Å; V141-L155 HydrophobicContact CG1-CD2 3.83Å; V141-L155 HydrophobicContact CG1-CG 4.11Å; R151-L155 WeakPolarHBondContact O-CB 3.4Å; R151-L155 WeakPolarHBondContact O-CG 3.46Å; R151-L155 PolarHBondContact O-N 2.96Å; Y152-L155 PolarHBondContact O-N 3.5Å; I153-L155 VanDerWaalsContact C-N 3.33Å; I153-L155 PolarHBondContact O-N 3.3Å; L155-A158 PolarHBondContact O-N 3.11Å; L155-R159 WeakPolarHBondContact O-CB 3.46Å; L155-R159 PolarHBondContact O-N 3.32Å
156	I	81.7	Confident	80.9	Confident	76 Å²	76	88.4 Å²	88.4	39%	0.39	50%	0.495	S	S	.	.	H	α-helix	trans	-71.6	-37.6	179	-151.5	156.1	0	0	0	111.9	Y152 I153 R159 L160	Y152-I156 PolarHBondContact O-N 2.87Å; I153-I156 WeakPolarHBondContact O-CG2 3.17Å; I153-I156 PolarHBondContact O-N 3.44Å; I156-R159 WeakPolarHBondContact O-CB 3.31Å; I156-R159 PolarHBondContact O-N 2.8Å; I156-L160 PolarHBondContact O-N 2.93Å
157	T	85.3	Confident	82.3	Confident	86 Å²	86	86.2 Å²	86.2	53%	0.528	47%	0.472	S	S	.	.	H	α-helix	trans	-65.6	-43.2	173.4	-50.1	0	0	0	0	110.8	I153 R159 L160 S161	I153-T157 WeakPolarHBondContact O-CB 3.4Å; I153-T157 PolarHBondContact O-N 2.86Å; I153-T157 PolarHBondContact O-OG1 3.41Å; T157-R159 PolarHBondContact O-N 3.36Å; T157-L160 PolarHBondContact O-N 3.26Å; T157-S161 WeakPolarHBondContact O-CB 3.48Å; T157-S161 PolarHBondContact O-N 3.15Å; T157-S161 PolarHBondContact O-OG 3.39Å
158	A	82.6	Confident	83.5	Confident	49 Å²	49	92.8 Å²	92.8	41%	0.405	48%	0.484	S	S	.	.	H	α-helix	trans	-58.9	-44.7	174	0	0	0	0	0	111.7	V154 L155 S161 L162	V154-A158 VanDerWaalsContact O-CB 3.29Å; V154-A158 WeakPolarHBondContact O-CB 3.17Å; V154-A158 PolarHBondContact O-N 2.65Å; L155-A158 PolarHBondContact O-N 3.11Å; A158-S161 WeakPolarHBondContact CA-OG 3.43Å; A158-S161 PolarHBondContact O-N 2.93Å; A158-S161 PolarHBondContact O-OG 3.48Å; A158-L162 WeakPolarHBondContact O-CB 3.12Å; A158-L162 PolarHBondContact O-N 3.1Å
159	R	80.2	Confident	84.2	Confident	90 Å²	90	91.4 Å²	91.4	34%	0.34	47%	0.473	S	S	.	.	H	α-helix	trans	-57.8	-52.3	174.6	167.1	-179.2	-179.4	161.8	11.3	112.3	V138 L155 I156 T157 S161 L162 L163	V138-R159 HydrophobicContact CG1-CG 3.88Å; V138-R159 HydrophobicContact CG2-CG 4.03Å; L155-R159 WeakPolarHBondContact O-CB 3.46Å; L155-R159 PolarHBondContact O-N 3.32Å; I156-R159 WeakPolarHBondContact O-CB 3.31Å; I156-R159 PolarHBondContact O-N 2.8Å; T157-R159 PolarHBondContact O-N 3.36Å; R159-S161 VanDerWaalsContact C-N 3.28Å; R159-S161 PolarHBondContact O-N 3.39Å; R159-L162 PolarHBondContact O-N 3.46Å; R159-L163 HydrophobicContact CG-CD1 3.88Å; R159-L163 PolarHBondContact O-N 3.37Å
160	L	83.1	Confident	84.7	Confident	117 Å²	117	86.9 Å²	86.9	61%	0.613	45%	0.449	S	S	*	.	H	α-helix	trans	-61.7	-43.4	-178.4	-173.3	64.3	0	0	0	109.9	I156 T157 L162 L163 T164	I156-L160 PolarHBondContact O-N 2.93Å; T157-L160 PolarHBondContact O-N 3.26Å; L160-L162 PolarHBondContact O-N 3.42Å; L160-L163 PolarHBondContact O-N 3.1Å; L160-T164 HydrophobicContact CD1-CG2 4.33Å; L160-T164 HydrophobicContact CG-CG2 4.35Å; L160-T164 WeakPolarHBondContact O-CB 3.48Å; L160-T164 VanDerWaalsContact O-CG2 3.28Å; L160-T164 WeakPolarHBondContact O-CG2 3.48Å; L160-T164 PolarHBondContact O-N 2.81Å; L160-T164 PolarHBondContact O-OG1 2.88Å
161	S	86.9	Confident	85.2	Confident	57 Å²	57	84 Å²	84	40%	0.399	44%	0.439	S	S	.	.	H	α-helix	trans	-59.4	-46.1	176.7	77.6	0	0	0	0	112	T157 A158 R159 L163 T164 M165	T157-S161 WeakPolarHBondContact O-CB 3.48Å; T157-S161 PolarHBondContact O-N 3.15Å; T157-S161 PolarHBondContact O-OG 3.39Å; A158-S161 WeakPolarHBondContact CA-OG 3.43Å; A158-S161 PolarHBondContact O-N 2.93Å; A158-S161 PolarHBondContact O-OG 3.48Å; R159-S161 VanDerWaalsContact C-N 3.28Å; R159-S161 PolarHBondContact O-N 3.39Å; S161-L163 PolarHBondContact O-N 3.24Å; S161-T164 WeakPolarHBondContact CA-OG1 3.47Å; S161-T164 PolarHBondContact O-N 3.2Å; S161-T164 PolarHBondContact O-OG1 3.27Å; S161-M165 VanDerWaalsContact O-CB 3.31Å; S161-M165 WeakPolarHBondContact O-CB 3.46Å; S161-M165 WeakPolarHBondContact O-CG 3.44Å; S161-M165 PolarHBondContact O-N 3.36Å
162	L	87.2	Confident	86	Confident	67 Å²	67	81.9 Å²	81.9	35%	0.351	43%	0.431	S	S	.	.	H	α-helix	trans	-63.2	-45.3	-179.9	-177.8	66.5	0	0	0	111.7	V134 I137 A158 R159 L160 M165 C166	V134-L162 HydrophobicContact CG1-CD2 4Å; V134-L162 HydrophobicContact CG1-CG 4.16Å; I137-L162 HydrophobicContact CG2-CD2 4.34Å; A158-L162 WeakPolarHBondContact O-CB 3.12Å; A158-L162 PolarHBondContact O-N 3.1Å; R159-L162 PolarHBondContact O-N 3.46Å; L160-L162 PolarHBondContact O-N 3.42Å; L162-M165 PolarHBondContact O-N 3.33Å; L162-C166 VanDerWaalsContact O-CB 3.25Å; L162-C166 WeakPolarHBondContact O-CB 3.37Å; L162-C166 PolarHBondContact O-N 2.72Å
163	L	85.3	Confident	86.5	Confident	71 Å²	71	76.5 Å²	76.5	37%	0.372	41%	0.41	S	S	.	.	H	α-helix	trans	-63.9	-44.7	176.3	-90.6	146.3	0	0	0	111.8	V138 R159 L160 S161 C166 G167	V138-L163 HydrophobicContact CG1-CD1 4.27Å; V138-L163 HydrophobicContact CG2-CD1 4.07Å; R159-L163 HydrophobicContact CG-CD1 3.88Å; R159-L163 PolarHBondContact O-N 3.37Å; L160-L163 PolarHBondContact O-N 3.1Å; S161-L163 PolarHBondContact O-N 3.24Å; L163-C166 PolarHBondContact O-N 2.91Å; L163-G167 PolarHBondContact O-N 2.91Å
164	T	87.4	Confident	86.7	Confident	76 Å²	76	75.4 Å²	75.4	47%	0.466	41%	0.405	S	S	.	.	H	α-helix	trans	-65.6	-38.8	177.7	54.1	0	0	0	0	111.9	L160 S161 W168	L160-T164 HydrophobicContact CD1-CG2 4.33Å; L160-T164 HydrophobicContact CG-CG2 4.35Å; L160-T164 WeakPolarHBondContact O-CB 3.48Å; L160-T164 VanDerWaalsContact O-CG2 3.28Å; L160-T164 WeakPolarHBondContact O-CG2 3.48Å; L160-T164 PolarHBondContact O-N 2.81Å; L160-T164 PolarHBondContact O-OG1 2.88Å; S161-T164 WeakPolarHBondContact CA-OG1 3.47Å; S161-T164 PolarHBondContact O-N 3.2Å; S161-T164 PolarHBondContact O-OG1 3.27Å; T164-W168 WeakPolarHBondContact O-CB 3.49Å; T164-W168 PolarHBondContact O-N 2.98Å
165	M	88.7	Confident	87	Confident	121 Å²	121	75.4 Å²	75.4	60%	0.596	41%	0.405	S	S	*	.	H	α-helix	trans	-68.4	-44.3	178	-71.6	-64.4	166.7	0	0	111.1	S161 L162 W168 V169	S161-M165 VanDerWaalsContact O-CB 3.31Å; S161-M165 WeakPolarHBondContact O-CB 3.46Å; S161-M165 WeakPolarHBondContact O-CG 3.44Å; S161-M165 PolarHBondContact O-N 3.36Å; L162-M165 PolarHBondContact O-N 3.33Å; M165-W168 PolarHBondContact O-N 3.45Å; M165-V169 VanDerWaalsContact O-CG2 3.28Å; M165-V169 WeakPolarHBondContact O-CG2 3.46Å; M165-V169 PolarHBondContact O-N 2.97Å
166	C	87.8	Confident	87.3	Confident	27 Å²	27	73.6 Å²	73.6	18%	0.182	40%	0.396	C	S	.	.	H	α-helix	trans	-60	-47.7	175.2	-175.8	0	0	0	0	111.5	V127 L162 L163 V169 L170	V127-C166 WeakPolarHBondContact CG1-SG 3.38Å; L162-C166 VanDerWaalsContact O-CB 3.25Å; L162-C166 WeakPolarHBondContact O-CB 3.37Å; L162-C166 PolarHBondContact O-N 2.72Å; L163-C166 PolarHBondContact O-N 2.91Å; C166-V169 PolarHBondContact O-N 3.16Å; C166-L170 WeakPolarHBondContact O-CG 3.47Å; C166-L170 PolarHBondContact O-N 2.91Å
167	G	88.4	Confident	87.6	Confident	37 Å²	37	70 Å²	70	38%	0.381	38%	0.377	S	S	.	.	H	α-helix	trans	-64.1	-40.2	176.6	0	0	0	0	0	113.4	L163 L170 C171	L163-G167 PolarHBondContact O-N 2.91Å; G167-L170 PolarHBondContact O-N 2.89Å; G167-C171 WeakPolarHBondContact O-CB 3.4Å; G167-C171 PolarHBondContact O-N 3.35Å
168	W	92.6	Very high	87.6	Confident	181 Å²	181	69.1 Å²	69.1	69%	0.686	37%	0.374	S	S	*	.	H	α-helix	trans	-62	-48	175.5	177.3	-91.2	0	0	0	111.6	T164 M165 L170 C171 W172	T164-W168 WeakPolarHBondContact O-CB 3.49Å; T164-W168 PolarHBondContact O-N 2.98Å; M165-W168 PolarHBondContact O-N 3.45Å; W168-L170 VanDerWaalsContact C-N 3.35Å; W168-L170 PolarHBondContact O-N 3.23Å; W168-C171 PolarHBondContact O-N 2.93Å; W168-W172 VanDerWaalsContact O-CB 3.29Å; W168-W172 WeakPolarHBondContact O-CB 3.17Å; W168-W172 PolarHBondContact O-N 3.41Å
169	V	91.4	Very high	87.7	Confident	41 Å²	41	77 Å²	77	25%	0.248	39%	0.393	C	S	.	.	H	α-helix	trans	-63.7	-40.5	178.3	174.9	0	0	0	0	111.1	I123 V127 M165 C166 W172 T173	I123-V169 HydrophobicContact CG2-CG1 3.58Å; V127-V169 HydrophobicContact CG2-CG1 3.88Å; M165-V169 VanDerWaalsContact O-CG2 3.28Å; M165-V169 WeakPolarHBondContact O-CG2 3.46Å; M165-V169 PolarHBondContact O-N 2.97Å; C166-V169 PolarHBondContact O-N 3.16Å; V169-W172 PolarHBondContact O-N 3.27Å; V169-T173 HydrophobicContact CG1-CG2 4.33Å; V169-T173 WeakPolarHBondContact O-CB 3.33Å; V169-T173 WeakPolarHBondContact O-CG2 3.37Å; V169-T173 PolarHBondContact O-N 2.91Å; V169-T173 PolarHBondContact O-OG1 3.32Å
170	L	88.6	Confident	87.9	Confident	44 Å²	44	77.1 Å²	77.1	23%	0.23	40%	0.401	C	S	.	.	H	α-helix	trans	-60.6	-46.4	173.3	-76.5	171.7	0	0	0	111.9	F124 V127 M128 C166 G167 W168 T173 L174	F124-L170 HydrophobicContact CD2-CD2 3.9Å; F124-L170 HydrophobicContact CE2-CD2 4Å; V127-L170 HydrophobicContact CB-CD2 3.74Å; V127-L170 HydrophobicContact CB-CG 4.15Å; V127-L170 HydrophobicContact CG1-CD1 3.9Å; V127-L170 HydrophobicContact CG1-CD2 3.59Å; V127-L170 HydrophobicContact CG1-CG 3.46Å; V127-L170 VanDerWaalsContact CG1-CG 3.46Å; M128-L170 HydrophobicContact CG-CD2 4.13Å; M128-L170 HydrophobicContact SD-CD1 4.47Å; M128-L170 HydrophobicContact SD-CD2 3.86Å; C166-L170 WeakPolarHBondContact O-CG 3.47Å; C166-L170 PolarHBondContact O-N 2.91Å; G167-L170 PolarHBondContact O-N 2.89Å; W168-L170 VanDerWaalsContact C-N 3.35Å; W168-L170 PolarHBondContact O-N 3.23Å; L170-T173 WeakPolarHBondContact CA-OG1 3.36Å; L170-T173 PolarHBondContact O-OG1 3.14Å; L170-L174 WeakPolarHBondContact O-CB 3.44Å; L170-L174 PolarHBondContact O-N 2.67Å
171	C	90.4	Very high	88	Confident	75 Å²	75	73.9 Å²	73.9	51%	0.507	38%	0.382	S	S	.	.	H	α-helix	trans	-64.9	-45.5	179.3	-172.4	0	0	0	0	111.3	G167 W168 T173 L174 V175	G167-C171 WeakPolarHBondContact O-CB 3.4Å; G167-C171 PolarHBondContact O-N 3.35Å; W168-C171 PolarHBondContact O-N 2.93Å; C171-T173 PolarHBondContact O-N 3.27Å; C171-L174 PolarHBondContact O-N 3.01Å; C171-V175 VanDerWaalsContact O-CG2 3.3Å; C171-V175 WeakPolarHBondContact O-CG2 3.11Å; C171-V175 PolarHBondContact O-N 2.95Å
172	W	92.9	Very high	87.9	Confident	134 Å²	134	74.2 Å²	74.2	51%	0.508	38%	0.384	S	S	.	.	H	α-helix	trans	-61	-46.4	178.5	176.2	56.1	0	0	0	112.3	W168 V169 N176	W168-W172 VanDerWaalsContact O-CB 3.29Å; W168-W172 WeakPolarHBondContact O-CB 3.17Å; W168-W172 PolarHBondContact O-N 3.41Å; V169-W172 PolarHBondContact O-N 3.27Å; W172-N176 WeakPolarHBondContact O-CB 3.33Å; W172-N176 PolarHBondContact O-N 3.16Å; W172-N176 VanDerWaalsContact O-N 3.12Å
173	T	90.4	Very high	87.6	Confident	1 Å²	1	76.8 Å²	76.8	1%	0.006	40%	0.403	C	S	.	.	H	α-helix	trans	-65.5	-40	176.2	50.4	0	0	0	0	112.1	I123 V169 L170 C171 N176 L177	I123-T173 HydrophobicContact CB-CG2 3.91Å; I123-T173 HydrophobicContact CG2-CG2 3.64Å; V169-T173 HydrophobicContact CG1-CG2 4.33Å; V169-T173 WeakPolarHBondContact O-CB 3.33Å; V169-T173 WeakPolarHBondContact O-CG2 3.37Å; V169-T173 PolarHBondContact O-N 2.91Å; V169-T173 PolarHBondContact O-OG1 3.32Å; L170-T173 WeakPolarHBondContact CA-OG1 3.36Å; L170-T173 PolarHBondContact O-OG1 3.14Å; C171-T173 PolarHBondContact O-N 3.27Å; T173-N176 PolarHBondContact O-N 3.48Å; T173-L177 WeakPolarHBondContact O-CB 3.14Å; T173-L177 PolarHBondContact O-N 3.36Å
174	L	87.5	Confident	87.3	Confident	71 Å²	71	79.5 Å²	79.5	37%	0.372	42%	0.417	S	S	.	.	H	α-helix	trans	-64	-46.9	177	-176	64.5	0	0	0	112	L170 C171 N176 L177 C178 L186 L189	L170-L174 WeakPolarHBondContact O-CB 3.44Å; L170-L174 PolarHBondContact O-N 2.67Å; C171-L174 PolarHBondContact O-N 3.01Å; L174-N176 VanDerWaalsContact C-N 3.27Å; L174-N176 PolarHBondContact O-N 2.97Å; L174-L177 PolarHBondContact O-N 3.05Å; L174-C178 WeakPolarHBondContact O-CB 3.35Å; L174-C178 PolarHBondContact O-N 2.96Å; L174-C178 PolarHBondContact O-SG 3.48Å; L174-L186 HydrophobicContact CD1-CD2 4.28Å; L174-L189 HydrophobicContact CD1-CD2 4.01Å
175	V	88.9	Confident	87	Confident	92 Å²	92	77.8 Å²	77.8	56%	0.558	41%	0.405	S	S	*	.	H	α-helix	trans	-59.3	-42.1	177.3	169.3	0	0	0	0	110.8	C171 C178 R179	C171-V175 VanDerWaalsContact O-CG2 3.3Å; C171-V175 WeakPolarHBondContact O-CG2 3.11Å; C171-V175 PolarHBondContact O-N 2.95Å; V175-C178 WeakPolarHBondContact O-CB 3.46Å; V175-C178 PolarHBondContact O-N 2.83Å; V175-R179 PolarHBondContact O-N 2.93Å
176	N	87.3	Confident	86.6	Confident	32 Å²	32	73.5 Å²	73.5	17%	0.171	38%	0.384	C	S	.	.	H	α-helix	trans	-70.7	-36	179	-165.7	76.9	0	0	0	112.5	H120 W172 T173 L174 C178 R179 N180	H120-N176 PolarHBondContact CD2-ND2 2.69Å; H120-N176 PolarHBondContact CE1-ND2 2.99Å; H120-N176 PolarHBondContact ND1-ND2 3.39Å; H120-N176 PolarHBondContact NE2-ND2 3.22Å; W172-N176 WeakPolarHBondContact O-CB 3.33Å; W172-N176 PolarHBondContact O-N 3.16Å; W172-N176 VanDerWaalsContact O-N 3.12Å; T173-N176 PolarHBondContact O-N 3.48Å; L174-N176 VanDerWaalsContact C-N 3.27Å; L174-N176 PolarHBondContact O-N 2.97Å; N176-C178 VanDerWaalsContact C-N 3.33Å; N176-R179 PolarHBondContact O-N 2.91Å; N176-N180 PolarHBondContact ND2-ND2 2.85Å; N176-N180 VanDerWaalsContact ND2-ND2 3.1Å; N176-N180 WeakPolarHBondContact O-CB 3.41Å; N176-N180 PolarHBondContact O-N 2.83Å; N176-N180 VanDerWaalsContact O-N 3.09Å
177	L	87.1	Confident	86.4	Confident	1 Å²	1	77.6 Å²	77.6	1%	0.005	40%	0.404	C	S	.	.	H	α-helix	trans	-65.2	-38.8	173	-158.1	75.7	0	0	0	111.3	L121 T173 L174 R179 N180 H181 L186 L189 F309	L121-L177 HydrophobicContact CB-CD1 4.28Å; L121-L177 HydrophobicContact CD1-CD2 4.44Å; T173-L177 WeakPolarHBondContact O-CB 3.14Å; T173-L177 PolarHBondContact O-N 3.36Å; L174-L177 PolarHBondContact O-N 3.05Å; L177-R179 VanDerWaalsContact C-N 3.27Å; L177-R179 PolarHBondContact O-N 3.39Å; L177-N180 PolarHBondContact O-N 3.09Å; L177-H181 WeakPolarHBondContact CD1-CD2 3.27Å; L177-H181 WeakPolarHBondContact O-CB 3.48Å; L177-H181 PolarHBondContact O-N 3.34Å; L177-L186 HydrophobicContact CB-CD2 4.24Å; L177-L186 HydrophobicContact CD2-CD2 4.08Å; L177-L186 HydrophobicContact CG-CD2 4.2Å; L177-L189 HydrophobicContact CD2-CD1 3.57Å; L177-L189 HydrophobicContact CD2-CD2 3.44Å; L177-L189 VanDerWaalsContact CD2-CD2 3.44Å; L177-L189 HydrophobicContact CD2-CG 4.17Å; L177-F309 HydrophobicContact CD1-CD1 4.37Å; L177-F309 HydrophobicContact CD1-CE1 3.86Å; L177-F309 HydrophobicContact CD2-CE1 3.97Å; L177-F309 HydrophobicContact CD2-CZ 3.92Å; L177-F309 HydrophobicContact CG-CE1 4.06Å; L177-F309 HydrophobicContact CG-CZ 4.49Å
178	C	85.4	Confident	86.2	Confident	68 Å²	68	79.5 Å²	79.5	46%	0.459	40%	0.402	S	S	.	.	H	α-helix	trans	-61.2	-35	173.4	-71.6	0	0	0	0	112.9	L174 V175 N176 L186	L174-C178 WeakPolarHBondContact O-CB 3.35Å; L174-C178 PolarHBondContact O-N 2.96Å; L174-C178 PolarHBondContact O-SG 3.48Å; V175-C178 WeakPolarHBondContact O-CB 3.46Å; V175-C178 PolarHBondContact O-N 2.83Å; N176-C178 VanDerWaalsContact C-N 3.33Å; C178-L186 HydrophobicContact CB-CD1 4.36Å; C178-L186 HydrophobicContact CB-CD2 4.39Å; C178-L186 WeakPolarHBondContact SG-CD2 3.2Å
179	R	85.6	Confident	85.8	Confident	213 Å²	213	71.4 Å²	71.4	80%	0.804	37%	0.372	S	S	*	.	H	α-helix	trans	-76.6	-32.9	179.7	-172.4	176.7	174.2	178.3	-1.8	112.6	V175 N176 L177	V175-R179 PolarHBondContact O-N 2.93Å; N176-R179 PolarHBondContact O-N 2.91Å; L177-R179 VanDerWaalsContact C-N 3.27Å; L177-R179 PolarHBondContact O-N 3.39Å
180	N	83.4	Confident	85.2	Confident	94 Å²	94	71 Å²	71	50%	0.503	38%	0.376	S	S	.	.	H	α-helix	trans	-99.2	-21.5	-170.5	-67	-9.9	0	0	0	114	N176 L177	N176-N180 PolarHBondContact ND2-ND2 2.85Å; N176-N180 VanDerWaalsContact ND2-ND2 3.1Å; N176-N180 WeakPolarHBondContact O-CB 3.41Å; N176-N180 PolarHBondContact O-N 2.83Å; N176-N180 VanDerWaalsContact O-N 3.09Å; L177-N180 PolarHBondContact O-N 3.09Å
181	H	84.8	Confident	84.9	Confident	49 Å²	49	74.9 Å²	74.9	23%	0.227	39%	0.389	C	S	.	.	S	Bend	trans	-122.2	158.6	-175.9	-67.2	-82.8	0	0	0	113.3	D118 L177 N185 F309	D118-H181 IonicContact OD2-CD2 3.65Å; D118-H181 IonicContact OD2-CE1 3.71Å; D118-H181 IonicContact OD2-NE2 2.72Å; D118-H181 PolarHBondContact OD2-NE2 3.05Å; L177-H181 WeakPolarHBondContact CD1-CD2 3.27Å; L177-H181 WeakPolarHBondContact O-CB 3.48Å; L177-H181 PolarHBondContact O-N 3.34Å; H181-N185 HydrophobicContact CB-CB 4.22Å; H181-F309 HydrophobicContact CB-CE1 4.19Å; H181-F309 AromaticContact CD2-CE1 3.91Å; H181-F309 AromaticContact CE1-CD1 3.65Å; H181-F309 AromaticContact CG-CD1 4Å; H181-F309 AromaticContact CG-CE1 3.76Å; H181-F309 AromaticContact ND1-CD1 3.73Å; H181-F309 AromaticContact ND1-CE1 3.95Å; H181-F309 AromaticContact NE2-CD1 3.86Å
182	S	84.7	Confident	84.2	Confident	63 Å²	63	71.8 Å²	71.8	44%	0.441	37%	0.368	S	S	.	.			trans	-67.8	152.6	176.4	68.1	0	0	0	0	111.9	L184 N185 L186	S182-L184 PolarHBondContact O-N 3.01Å; S182-L184 VanDerWaalsContact O-N 3.14Å; S182-N185 WeakPolarHBondContact O-CB 3.5Å; S182-N185 PolarHBondContact O-N 2.95Å; S182-L186 WeakPolarHBondContact O-CD1 3.4Å; S182-L186 PolarHBondContact O-N 3.45Å
183	V	80.5	Confident	83.2	Confident	121 Å²	121	68.9 Å²	68.9	73%	0.733	36%	0.359	S	S	*	.	H	α-helix	trans	-56.2	-30.9	178.6	-177.4	0	0	0	0	112.5	L186 L187	V183-L186 WeakPolarHBondContact O-CB 3.14Å; V183-L186 PolarHBondContact O-N 2.97Å; V183-L187 PolarHBondContact O-N 3.42Å
184	L	79.6	Confident	82.2	Confident	128 Å²	128	71.2 Å²	71.2	67%	0.67	38%	0.383	S	S	*	.	H	α-helix	trans	-64.7	-42.2	175.7	-69.5	173.2	0	0	0	112.3	S182 L186 L187 F188	S182-L184 PolarHBondContact O-N 3.01Å; S182-L184 VanDerWaalsContact O-N 3.14Å; L184-L186 VanDerWaalsContact C-N 3.26Å; L184-L186 PolarHBondContact O-N 2.97Å; L184-L187 WeakPolarHBondContact O-CB 3.27Å; L184-L187 PolarHBondContact O-N 2.97Å; L184-F188 WeakPolarHBondContact O-CD2 3.09Å; L184-F188 PolarHBondContact O-N 3.32Å
185	N	80.5	Confident	81.3	Confident	41 Å²	41	70.6 Å²	70.6	22%	0.219	38%	0.382	C	S	.	.	H	α-helix	trans	-65.3	-35.4	176.7	-70.2	-2.4	0	0	0	111.4	H181 S182 L187 F188 F309	H181-N185 HydrophobicContact CB-CB 4.22Å; S182-N185 WeakPolarHBondContact O-CB 3.5Å; S182-N185 PolarHBondContact O-N 2.95Å; N185-L187 VanDerWaalsContact C-N 3.33Å; N185-F188 PolarHBondContact O-N 3.29Å; N185-F309 HydrophobicContact CB-CE1 3.88Å; N185-F309 HydrophobicContact CB-CZ 3.86Å; N185-F309 WeakPolarHBondContact O-CZ 3.34Å
186	L	81.9	Confident	80.2	Confident	30 Å²	30	67.5 Å²	67.5	16%	0.157	36%	0.36	C	S	.	.	H	α-helix	trans	-69.9	-28.6	175.5	-73.1	142.6	0	0	0	112.9	L174 L177 C178 S182 V183 L184 F188 L189	L174-L186 HydrophobicContact CD1-CD2 4.28Å; L177-L186 HydrophobicContact CB-CD2 4.24Å; L177-L186 HydrophobicContact CD2-CD2 4.08Å; L177-L186 HydrophobicContact CG-CD2 4.2Å; C178-L186 HydrophobicContact CB-CD1 4.36Å; C178-L186 HydrophobicContact CB-CD2 4.39Å; C178-L186 WeakPolarHBondContact SG-CD2 3.2Å; S182-L186 WeakPolarHBondContact O-CD1 3.4Å; S182-L186 PolarHBondContact O-N 3.45Å; V183-L186 WeakPolarHBondContact O-CB 3.14Å; V183-L186 PolarHBondContact O-N 2.97Å; L184-L186 VanDerWaalsContact C-N 3.26Å; L184-L186 PolarHBondContact O-N 2.97Å; L186-F188 VanDerWaalsContact C-N 3.29Å; L186-F188 PolarHBondContact O-N 3.47Å; L186-L189 WeakPolarHBondContact O-CB 3.24Å; L186-L189 PolarHBondContact O-N 2.92Å
187	L	83.4	Confident	79.1	Confident	113 Å²	113	67.4 Å²	67.4	59%	0.592	36%	0.361	S	S	*	.	H	α-helix	trans	-65.6	-35.1	175	-163.3	150.7	0	0	0	111.3	V183 L184 N185 L189 G190 Y191	V183-L187 PolarHBondContact O-N 3.42Å; L184-L187 WeakPolarHBondContact O-CB 3.27Å; L184-L187 PolarHBondContact O-N 2.97Å; N185-L187 VanDerWaalsContact C-N 3.33Å; L187-L189 VanDerWaalsContact C-N 3.27Å; L187-L189 PolarHBondContact O-N 3.39Å; L187-G190 PolarHBondContact O-N 2.97Å; L187-G190 VanDerWaalsContact O-N 3.08Å; L187-Y191 PolarHBondContact O-N 3.35Å
188	F	84.2	Confident	78.1	Confident	78 Å²	78	70.1 Å²	70.1	34%	0.342	38%	0.379	S	S	.	.	H	α-helix	trans	-61.6	-33.2	174.1	-66.5	-60.6	0	0	0	112.4	L184 N185 L186 G190 Y191 Y300 L305 C308	L184-F188 WeakPolarHBondContact O-CD2 3.09Å; L184-F188 PolarHBondContact O-N 3.32Å; N185-F188 PolarHBondContact O-N 3.29Å; L186-F188 VanDerWaalsContact C-N 3.29Å; L186-F188 PolarHBondContact O-N 3.47Å; F188-G190 PolarHBondContact O-N 3.4Å; F188-Y191 PolarHBondContact O-N 3.09Å; F188-Y300 WeakPolarHBondContact O-CE1 3.4Å; F188-Y300 PolarHBondContact O-OH 3.43Å; F188-L305 HydrophobicContact CB-CD1 4.32Å; F188-C308 HydrophobicContact CD2-CB 4.37Å
189	L	83.6	Confident	77	Confident	10 Å²	10	72.4 Å²	72.4	5%	0.052	39%	0.386	C	S	.	.	H	α-helix	trans	-58.3	-33.1	174.3	-102.3	74.3	0	0	0	112.9	L121 F124 L174 L177 L186 L187 Y301 L305 F309	L121-L189 HydrophobicContact CD1-CD1 4.36Å; F124-L189 HydrophobicContact CD1-CD2 3.78Å; F124-L189 HydrophobicContact CD1-CG 4.17Å; F124-L189 HydrophobicContact CD2-CD2 4.29Å; F124-L189 HydrophobicContact CE1-CD2 3.35Å; F124-L189 HydrophobicContact CE1-CG 3.56Å; F124-L189 HydrophobicContact CE2-CD2 3.9Å; F124-L189 HydrophobicContact CG-CD2 4.24Å; F124-L189 HydrophobicContact CZ-CD2 3.43Å; F124-L189 VanDerWaalsContact CZ-CD2 3.43Å; F124-L189 HydrophobicContact CZ-CG 3.97Å; L174-L189 HydrophobicContact CD1-CD2 4.01Å; L177-L189 HydrophobicContact CD2-CD1 3.57Å; L177-L189 HydrophobicContact CD2-CD2 3.44Å; L177-L189 VanDerWaalsContact CD2-CD2 3.44Å; L177-L189 HydrophobicContact CD2-CG 4.17Å; L186-L189 WeakPolarHBondContact O-CB 3.24Å; L186-L189 PolarHBondContact O-N 2.92Å; L187-L189 VanDerWaalsContact C-N 3.27Å; L187-L189 PolarHBondContact O-N 3.39Å; L189-Y301 PolarHBondContact O-OH 2.95Å; L189-L305 HydrophobicContact CD1-CD1 4.07Å; L189-L305 HydrophobicContact CD1-CD2 4.21Å; L189-L305 HydrophobicContact CG-CD2 4.38Å; L189-F309 HydrophobicContact CD1-CE2 3.51Å; L189-F309 HydrophobicContact CD1-CZ 3.37Å
190	G	78.7	Confident	75.6	Confident	34 Å²	34	63.7 Å²	63.7	35%	0.351	36%	0.357	S	S	.	.	H	α-helix	trans	-94.7	-6.2	-177.4	0	0	0	0	0	114.8	L187 F188 F193 G194	L187-G190 PolarHBondContact O-N 2.97Å; L187-G190 VanDerWaalsContact O-N 3.08Å; F188-G190 PolarHBondContact O-N 3.4Å; G190-F193 WeakPolarHBondContact O-CB 3.36Å; G190-F193 PolarHBondContact O-N 3.34Å; G190-G194 PolarHBondContact O-N 3.36Å
191	Y	81.8	Confident	74.4	Confident	125 Å²	125	60.6 Å²	60.6	49%	0.49	34%	0.343	S	S	.	.	H	α-helix	trans	-57.4	-44.4	-170.9	-178.8	-96.6	0	0	0	114.2	L187 F188 F193 G194 V195 Y300	L187-Y191 PolarHBondContact O-N 3.35Å; F188-Y191 PolarHBondContact O-N 3.09Å; Y191-F193 PolarHBondContact O-N 2.83Å; Y191-G194 PolarHBondContact O-N 2.87Å; Y191-G194 VanDerWaalsContact O-N 3.16Å; Y191-V195 HydrophobicContact CD1-CG2 4.24Å; Y191-V195 HydrophobicContact CD2-CG2 4.27Å; Y191-V195 HydrophobicContact CE1-CG2 3.76Å; Y191-V195 HydrophobicContact CE2-CG2 3.8Å; Y191-V195 HydrophobicContact CG-CG2 4.47Å; Y191-V195 PolarHBondContact O-N 3.06Å; Y191-Y300 AromaticContact CD1-CE2 3.96Å; Y191-Y300 HydrophobicContact CD1-CE2 3.96Å
192	P	77	Confident	73	Confident	10 Å²	10	65.6 Å²	65.6	7%	0.065	36%	0.364	C	S	.	.	H	α-helix	trans	-60.6	-32.1	176.8	-26	37.9	0	0	0	113.4	Y196 F297 Y300 Y301	P192-Y196 WeakPolarHBondContact O-CB 3.35Å; P192-Y196 PolarHBondContact O-N 3.29Å; P192-Y196 VanDerWaalsContact O-N 3.14Å; P192-F297 HydrophobicContact CB-CD2 3.75Å; P192-F297 HydrophobicContact CB-CE2 4.12Å; P192-F297 HydrophobicContact CG-CD2 4.48Å; P192-Y300 HydrophobicContact CG-CD1 3.3Å; P192-Y300 HydrophobicContact CG-CD2 4.28Å; P192-Y300 HydrophobicContact CG-CE1 3.52Å; P192-Y300 HydrophobicContact CG-CE2 4.45Å; P192-Y300 HydrophobicContact CG-CG 3.73Å; P192-Y301 HydrophobicContact CB-CE2 4.33Å; P192-Y301 HydrophobicContact CG-CE2 3.79Å
193	F	71.1	Confident	71.4	Confident	73 Å²	73	67.5 Å²	67.5	32%	0.32	37%	0.366	S	S	.	.	H	α-helix	trans	-74.7	-40	176.1	-62.7	-77.5	0	0	0	111.8	M128 G190 Y191 V195 Y196 V197 F297 Y301	M128-F193 HydrophobicContact CE-CE2 3.92Å; M128-F193 HydrophobicContact CE-CZ 3.69Å; G190-F193 WeakPolarHBondContact O-CB 3.36Å; G190-F193 PolarHBondContact O-N 3.34Å; Y191-F193 PolarHBondContact O-N 2.83Å; F193-V195 VanDerWaalsContact C-N 3.34Å; F193-V195 PolarHBondContact O-N 3.14Å; F193-Y196 PolarHBondContact O-N 3.27Å; F193-V197 VanDerWaalsContact O-CG2 3.32Å; F193-V197 WeakPolarHBondContact O-CG2 3.29Å; F193-V197 PolarHBondContact O-N 3.48Å; F193-F297 HydrophobicContact CE1-CE2 4.27Å; F193-F297 AromaticContact CE2-CE2 3.96Å; F193-F297 HydrophobicContact CE2-CE2 3.96Å; F193-F297 HydrophobicContact CE2-CZ 4.4Å; F193-F297 AromaticContact CZ-CE2 3.71Å; F193-F297 HydrophobicContact CZ-CE2 3.71Å; F193-F297 HydrophobicContact CZ-CZ 4.07Å; F193-Y301 WeakPolarHBondContact CE2-OH 3.17Å
194	G	69.6	Low	70	Confident	50 Å²	50	65.9 Å²	65.9	52%	0.515	35%	0.35	S	S	.	.	H	α-helix	trans	-65.5	-32.6	177.7	0	0	0	0	0	113.9	G190 Y191 P198	G190-G194 PolarHBondContact O-N 3.36Å; Y191-G194 PolarHBondContact O-N 2.87Å; Y191-G194 VanDerWaalsContact O-N 3.16Å; G194-P198 WeakPolarHBondContact O-CD 3.33Å; G194-P198 WeakPolarHBondContact O-CG 3.4Å
195	V	69.4	Low	68.4	Low	58 Å²	58	65.2 Å²	65.2	35%	0.352	34%	0.344	S	S	.	.	H	α-helix	trans	-82.8	-34.5	176.3	175.7	0	0	0	0	112	Y191 F193 L199	Y191-V195 HydrophobicContact CD1-CG2 4.24Å; Y191-V195 HydrophobicContact CD2-CG2 4.27Å; Y191-V195 HydrophobicContact CE1-CG2 3.76Å; Y191-V195 HydrophobicContact CE2-CG2 3.8Å; Y191-V195 HydrophobicContact CG-CG2 4.47Å; Y191-V195 PolarHBondContact O-N 3.06Å; F193-V195 VanDerWaalsContact C-N 3.34Å; F193-V195 PolarHBondContact O-N 3.14Å; V195-L199 HydrophobicContact CG1-CD1 3.67Å; V195-L199 WeakPolarHBondContact O-CD1 3.31Å; V195-L199 PolarHBondContact O-N 3.15Å
196	Y	65.3	Low	66.5	Low	26 Å²	26	66 Å²	66	10%	0.102	36%	0.361	C	S	.	.	H	α-helix	trans	-66.4	-43.9	-177.3	-178.5	-107.5	0	0	0	113.5	P192 F193 L199 C200 N245 Q249 F293	P192-Y196 WeakPolarHBondContact O-CB 3.35Å; P192-Y196 PolarHBondContact O-N 3.29Å; P192-Y196 VanDerWaalsContact O-N 3.14Å; F193-Y196 PolarHBondContact O-N 3.27Å; Y196-L199 PolarHBondContact O-N 2.89Å; Y196-C200 WeakPolarHBondContact CE2-SG 3.42Å; Y196-C200 PolarHBondContact O-N 2.89Å; Y196-C200 PolarHBondContact O-SG 2.82Å; Y196-N245 HydrophobicContact CE1-CB 4.25Å; Y196-Q249 VanDerWaalsContact CE1-CD 3.5Å; Y196-Q249 HydrophobicContact CE1-CG 3.98Å; Y196-Q249 WeakPolarHBondContact OH-CG 3.49Å; Y196-F293 HydrophobicContact CD1-CZ 4.48Å; Y196-F293 HydrophobicContact CD2-CB 4.43Å; Y196-F293 AromaticContact CD2-CD1 3.72Å; Y196-F293 HydrophobicContact CD2-CD1 3.72Å; Y196-F293 AromaticContact CD2-CD2 3.28Å; Y196-F293 HydrophobicContact CD2-CD2 3.28Å; Y196-F293 AromaticContact CD2-CE1 3.73Å; Y196-F293 HydrophobicContact CD2-CE1 3.73Å; Y196-F293 AromaticContact CD2-CE2 3.26Å; Y196-F293 HydrophobicContact CD2-CE2 3.26Å; Y196-F293 AromaticContact CD2-CG 3.49Å; Y196-F293 HydrophobicContact CD2-CG 3.49Å; Y196-F293 VanDerWaalsContact CD2-CG 3.49Å; Y196-F293 AromaticContact CD2-CZ 3.48Å; Y196-F293 HydrophobicContact CD2-CZ 3.48Å; Y196-F293 VanDerWaalsContact CD2-CZ 3.48Å; Y196-F293 HydrophobicContact CE2-CB 4.25Å; Y196-F293 AromaticContact CE2-CD1 3.58Å; Y196-F293 HydrophobicContact CE2-CD1 3.58Å; Y196-F293 AromaticContact CE2-CD2 3.9Å; Y196-F293 HydrophobicContact CE2-CD2 3.9Å; Y196-F293 AromaticContact CE2-CE1 3.88Å; Y196-F293 HydrophobicContact CE2-CE1 3.88Å; Y196-F293 HydrophobicContact CE2-CE2 4.15Å; Y196-F293 AromaticContact CE2-CG 3.58Å; Y196-F293 HydrophobicContact CE2-CG 3.58Å; Y196-F293 HydrophobicContact CE2-CZ 4.12Å; Y196-F293 HydrophobicContact CG-CD2 4.16Å; Y196-F293 HydrophobicContact CG-CE1 4.18Å; Y196-F293 AromaticContact CG-CE2 3.67Å; Y196-F293 HydrophobicContact CG-CE2 3.67Å; Y196-F293 AromaticContact CG-CZ 3.66Å; Y196-F293 HydrophobicContact CG-CZ 3.66Å
197	V	64.1	Low	64.5	Low	30 Å²	30	67.8 Å²	67.8	18%	0.182	39%	0.387	C	S	.	.	H	α-helix	trans	-64.4	-46.4	-172.3	173.1	0	0	0	0	112.1	F193 C200 C201 F238 L242	F193-V197 VanDerWaalsContact O-CG2 3.32Å; F193-V197 WeakPolarHBondContact O-CG2 3.29Å; F193-V197 PolarHBondContact O-N 3.48Å; V197-C200 PolarHBondContact O-N 3.18Å; V197-C201 PolarHBondContact O-N 3.31Å; V197-C201 VanDerWaalsContact O-N 3.09Å; V197-C201 PolarHBondContact O-SG 2.87Å; V197-F238 HydrophobicContact CG1-CD2 4.41Å; V197-F238 HydrophobicContact CG1-CE2 3.27Å; V197-F238 HydrophobicContact CG1-CZ 3.45Å; V197-F238 VanDerWaalsContact CG1-CZ 3.45Å; V197-L242 HydrophobicContact CG1-CD1 4.16Å; V197-L242 HydrophobicContact CG2-CD1 3.51Å
198	P	65.3	Low	62.2	Low	59 Å²	59	70.3 Å²	70.3	38%	0.383	39%	0.393	S	S	.	.	H	α-helix	trans	-62	-43.4	173	-23.7	34.3	0	0	0	113.3	G194 C200 C201 F202	G194-P198 WeakPolarHBondContact O-CD 3.33Å; G194-P198 WeakPolarHBondContact O-CG 3.4Å; P198-C200 VanDerWaalsContact C-N 3.26Å; P198-C200 PolarHBondContact O-N 3.45Å; P198-C201 PolarHBondContact O-N 3.12Å; P198-F202 HydrophobicContact CB-CD2 4.39Å; P198-F202 HydrophobicContact CB-CE2 4.32Å; P198-F202 WeakPolarHBondContact O-CD2 3.49Å; P198-F202 PolarHBondContact O-N 3.36Å
199	L	62.6	Low	59.5	Low	115 Å²	115	71.5 Å²	71.5	60%	0.602	41%	0.411	S	S	*	.	H	α-helix	trans	-60.9	-34.2	-179.6	-84.8	163.1	0	0	0	112.9	V195 Y196	V195-L199 HydrophobicContact CG1-CD1 3.67Å; V195-L199 WeakPolarHBondContact O-CD1 3.31Å; V195-L199 PolarHBondContact O-N 3.15Å; Y196-L199 PolarHBondContact O-N 2.89Å
200	C	57.1	Low	57.2	Low	31 Å²	31	76.8 Å²	76.8	21%	0.209	45%	0.446	C	S	.	.	H	α-helix	trans	-77.9	-41.2	176.8	-62	0	0	0	0	111.9	Y196 V197 P198 H203 Q204	Y196-C200 WeakPolarHBondContact CE2-SG 3.42Å; Y196-C200 PolarHBondContact O-N 2.89Å; Y196-C200 PolarHBondContact O-SG 2.82Å; V197-C200 PolarHBondContact O-N 3.18Å; P198-C200 VanDerWaalsContact C-N 3.26Å; P198-C200 PolarHBondContact O-N 3.45Å; C200-H203 PolarHBondContact O-N 2.77Å; C200-Q204 PolarHBondContact O-N 3.32Å
201	C	57.1	Low	54.8	Low	28 Å²	28	79.8 Å²	79.8	19%	0.189	47%	0.468	C	S	.	.	H	α-helix	trans	-60.2	-47.8	176.2	-67.5	0	0	0	0	112.2	V197 P198 H203 Q204 E205	V197-C201 PolarHBondContact O-N 3.31Å; V197-C201 VanDerWaalsContact O-N 3.09Å; V197-C201 PolarHBondContact O-SG 2.87Å; P198-C201 PolarHBondContact O-N 3.12Å; C201-H203 PolarHBondContact O-N 2.73Å; C201-Q204 PolarHBondContact O-N 2.72Å; C201-E205 PolarHBondContact O-N 3.49Å
202	F	56.2	Low	52.5	Low	155 Å²	155	80.2 Å²	80.2	68%	0.68	49%	0.485	S	S	*	.	H	α-helix	trans	-62.8	-26.1	178	-79.3	-63.9	0	0	0	113.3	P198	P198-F202 HydrophobicContact CB-CD2 4.39Å; P198-F202 HydrophobicContact CB-CE2 4.32Å; P198-F202 WeakPolarHBondContact O-CD2 3.49Å; P198-F202 PolarHBondContact O-N 3.36Å
203	H	50	Low	50.2	Low	103 Å²	103	83.4 Å²	83.4	48%	0.477	52%	0.521	S	S	.	.	H	α-helix	trans	-80	-35.2	179.8	-171.3	45.1	0	0	0	112.9	C200 C201 E205 G206 G207 K289	C200-H203 PolarHBondContact O-N 2.77Å; C201-H203 PolarHBondContact O-N 2.73Å; H203-E205 VanDerWaalsContact C-N 3.27Å; H203-E205 PolarHBondContact O-N 2.7Å; H203-G206 PolarHBondContact O-N 3.32Å; H203-G207 PolarHBondContact O-N 2.95Å; H203-K289 PolarHBondContact CD2-NZ 2.85Å; H203-K289 PolarHBondContact CE1-NZ 3.46Å; H203-K289 PolarHBondContact ND1-NZ 3.11Å; H203-K289 PolarHBondContact NE2-NZ 2.97Å
204	Q	52.1	Low	48.2	Very low	87 Å²	87	85.3 Å²	85.3	41%	0.407	54%	0.543	S	S	.	.	H	α-helix	trans	-67.7	-30.1	178.6	-156.5	175.3	41.2	0	0	112	C200 C201 G207	C200-Q204 PolarHBondContact O-N 3.32Å; C201-Q204 PolarHBondContact O-N 2.72Å; Q204-G207 PolarHBondContact O-N 2.87Å
205	E	44.7	Very low	46.2	Very low	114 Å²	114	90 Å²	90	53%	0.533	56%	0.556	S	S	.	*	H	α-helix	trans	-68.3	-36.1	172.4	-70.3	-179.1	168.9	0	0	112.5	C201 H203 G207 K208	C201-E205 PolarHBondContact O-N 3.49Å; H203-E205 VanDerWaalsContact C-N 3.27Å; H203-E205 PolarHBondContact O-N 2.7Å; E205-G207 VanDerWaalsContact C-N 3.26Å; E205-G207 PolarHBondContact O-N 3.09Å; E205-K208 PolarHBondContact O-N 3.28Å
206	G	41.3	Very low	44.2	Very low	57 Å²	57	93.6 Å²	93.6	59%	0.588	58%	0.582	S	S	*	*	H	α-helix	trans	-70.3	-16.6	177.8	0	0	0	0	0	115.1	H203	H203-G206 PolarHBondContact O-N 3.32Å
207	G	39.9	Very low	42.2	Very low	67 Å²	67	99.5 Å²	99.5	69%	0.691	61%	0.611	S	S	*	*	T	Hydrogen-bonded Turn	trans	-89.4	-12.3	176.8	0	0	0	0	0	114.5	H203 Q204 E205	H203-G207 PolarHBondContact O-N 2.95Å; Q204-G207 PolarHBondContact O-N 2.87Å; E205-G207 VanDerWaalsContact C-N 3.26Å; E205-G207 PolarHBondContact O-N 3.09Å
208	K	34.3	Very low	40.5	Very low	166 Å²	166	107.6 Å²	107.6	72%	0.722	64%	0.639	S	S	*	*			trans	-108.5	67.6	177	-70.5	179.8	179.7	172.9	0	110.3	E205 P210	E205-K208 PolarHBondContact O-N 3.28Å; K208-P210 WeakPolarHBondContact O-CD 3.37Å
209	S	27.6	Very low	39.1	Very low	104 Å²	104	110.2 Å²	110.2	73%	0.727	66%	0.657	S	S	*	*			trans	-89.7	114.3	158	-66.2	0	0	0	0	108.1	A211	S209-A211 PolarHBondContact O-N 3.49Å
210	P	36.5	Very low	37.4	Very low	121 Å²	121	109.3 Å²	109.3	79%	0.786	67%	0.665	S	S	*	*	P	Polyproline II helix	trans	-70.1	126.8	172.6	27.5	-29.3	0	0	0	108.9	K208	K208-P210 WeakPolarHBondContact O-CD 3.37Å
211	A	27	Very low	35.8	Very low	97 Å²	97	116.3 Å²	116.3	80%	0.802	70%	0.695	S	S	*	*	P	Polyproline II helix	trans	-61.7	144.5	169.4	0	0	0	0	0	110.3	S209	S209-A211 PolarHBondContact O-N 3.49Å
212	P	35.2	Very low	34.3	Very low	133 Å²	133	123.4 Å²	123.4	86%	0.864	73%	0.725	S	S	*	*	P	Polyproline II helix	trans	-90.1	141.5	-177.7	34.5	-31	0	0	0	112.5
213	G	27.8	Very low	32.8	Very low	78 Å²	78	124.1 Å²	124.1	80%	0.804	73%	0.731	S	S	*	*			trans	113.2	110.6	146.6	0	0	0	0	0	117.7
214	S	28.6	Very low	31.7	Very low	112 Å²	112	128.2 Å²	128.2	78%	0.783	75%	0.75	S	S	*	*				158.7	95.5	112	-175.4	0	0	0	0	112
215	D	27.4	Very low	30.5	Very low	150 Å²	150	127.9 Å²	127.9	80%	0.802	76%	0.763	S	S	*	*			trans	27.5	126.3	138.9	-50.3	-22.8	0	0	0	121.4
216	C	27.8	Very low	29.5	Very low	132 Å²	132	130.4 Å²	130.4	89%	0.892	78%	0.779	S	S	*	*				-173.2	118.8	113.3	-97.2	0	0	0	0	113.2
217	E	23.8	Very low	29.3	Very low	151 Å²	151	136.3 Å²	136.3	71%	0.706	80%	0.797	S	S	*	*			trans	-19.4	135.3	158.5	-102	161.6	130.4	0	0	121.3
218	Y	28.8	Very low	29	Very low	200 Å²	200	137.5 Å²	137.5	78%	0.784	80%	0.8	S	S	*	*				174.7	166.8	90.8	-97	-50	0	0	0	112.2
219	P	35.9	Very low	28.8	Very low	114 Å²	114	138.1 Å²	138.1	74%	0.74	81%	0.806	S	S	*	*			trans	-123.1	162.6	-144.5	31.3	-8.4	0	0	0	114.9
220	A	25.4	Very low	28.8	Very low	95 Å²	95	138.2 Å²	138.2	79%	0.785	81%	0.806	S	S	*	*			trans	-175.4	117.3	142.9	0	0	0	0	0	111.9
221	E	24.1	Very low	28.7	Very low	179 Å²	179	141.6 Å²	141.6	84%	0.836	81%	0.811	S	S	*	*			trans	17.3	125.3	148.6	-59.9	-177.3	101.5	0	0	120.9
222	Q	25	Very low	29.2	Very low	176 Å²	176	143.6 Å²	143.6	82%	0.822	81%	0.808	S	S	*	*				-175.8	138.8	101.1	-104.8	156	-22.6	0	0	114.3
223	Q	26.3	Very low	29.5	Very low	170 Å²	170	144.1 Å²	144.1	79%	0.794	80%	0.797	S	S	*	*			trans	74.9	90.3	159	-112.3	76.5	19.3	0	0	120.8
224	Q	25.7	Very low	30.1	Very low	189 Å²	189	148.9 Å²	148.9	88%	0.883	79%	0.791	S	S	*	*			trans	-42.9	125.1	142.9	-162.9	92	-1.1	0	0	113.1
225	A	26.6	Very low	31	Very low	81 Å²	81	147.8 Å²	147.8	67%	0.669	78%	0.781	S	S	*	*			trans	163.7	98	131.5	0	0	0	0	0	110.2
226	D	25.3	Very low	31.8	Very low	166 Å²	166	150.7 Å²	150.7	89%	0.888	78%	0.78	S	S	*	*				173.8	100.1	122.3	-87.7	-17.3	0	0	0	109.9
227	L	35.9	Very low	33.3	Very low	182 Å²	182	148.8 Å²	148.8	95%	0.953	76%	0.761	S	S	*	*			trans	-98.2	79.2	175.5	-163.7	107.1	0	0	0	107.6
228	A	34.1	Very low	34.6	Very low	92 Å²	92	145.4 Å²	145.4	76%	0.76	74%	0.744	S	S	*	*			trans	169	75.5	155.6	0	0	0	0	0	111.9
229	E	29.1	Very low	36	Very low	179 Å²	179	140.9 Å²	140.9	84%	0.836	73%	0.733	S	S	*	*			trans	-133.6	105.4	151	-98.7	-172.5	164.5	0	0	108.5	Q231	E229-Q231 PolarHBondContact O-N 2.92Å
230	S	28.7	Very low	37	Very low	105 Å²	105	141.2 Å²	141.2	73%	0.734	72%	0.723	S	S	*	*			trans	-41.2	127.9	160	37.9	0	0	0	0	109.8	L232	S230-L232 VanDerWaalsContact C-N 3.3Å; S230-L232 PolarHBondContact O-N 3.46Å
231	Q	34.9	Very low	38.3	Very low	192 Å²	192	138.5 Å²	138.5	90%	0.897	70%	0.695	S	S	*	*			trans	-36.8	87	173.2	-70.9	-92.3	-35.8	0	0	112.1	E229 F233	E229-Q231 PolarHBondContact O-N 2.92Å; Q231-F233 PolarHBondContact O-N 3.33Å
232	L	36.3	Very low	39.6	Very low	140 Å²	140	132.4 Å²	132.4	73%	0.733	67%	0.668	S	S	*	*			trans	-87.8	100.3	177.9	-150.1	148.9	0	0	0	105.6	S230 R234	S230-L232 VanDerWaalsContact C-N 3.3Å; S230-L232 PolarHBondContact O-N 3.46Å; L232-R234 PolarHBondContact O-N 3.46Å
233	F	42.6	Very low	41	Very low	144 Å²	144	131.9 Å²	131.9	63%	0.632	66%	0.659	S	S	*	*			trans	-34.1	111	173	-93.5	-94.8	0	0	0	110.4	Q231 P235	Q231-F233 PolarHBondContact O-N 3.33Å; F233-P235 VanDerWaalsContact O-CD 3.24Å; F233-P235 WeakPolarHBondContact O-CD 3.17Å; F233-P235 VanDerWaalsContact O-N 3.17Å
234	R	40.6	Very low	42.3	Very low	178 Å²	178	127.8 Å²	127.8	67%	0.672	64%	0.639	S	S	*	*			trans	-65.6	116.1	178.7	-177.4	174.3	-85.6	-179.5	-3.9	107.8	L232 R236 D237 F238	L232-R234 PolarHBondContact O-N 3.46Å; R234-R236 HydrophobicContact CG-CB 4.39Å; R234-R236 PolarHBondContact O-N 3.29Å; R234-D237 PolarHBondContact O-N 3.07Å; R234-F238 PolarHBondContact O-N 3.01Å
235	P	46.1	Very low	43.5	Very low	88 Å²	88	120.2 Å²	120.2	57%	0.571	61%	0.605	S	S	*	*	H	α-helix	trans	-63.9	-18.9	-171.8	21	-31.3	0	0	0	113.6	F233 L239	F233-P235 VanDerWaalsContact O-CD 3.24Å; F233-P235 WeakPolarHBondContact O-CD 3.17Å; F233-P235 VanDerWaalsContact O-N 3.17Å; P235-L239 WeakPolarHBondContact O-CB 3.47Å; P235-L239 WeakPolarHBondContact O-CG 3.22Å; P235-L239 PolarHBondContact O-N 3.41Å
236	R	46	Very low	44.7	Very low	212 Å²	212	119.6 Å²	119.6	80%	0.8	59%	0.59	S	S	*	*	H	α-helix	trans	-68	-37.3	173.2	-81.6	-176.6	172.8	178.4	-1.6	113	R234 F240	R234-R236 HydrophobicContact CG-CB 4.39Å; R234-R236 PolarHBondContact O-N 3.29Å; R236-F240 VanDerWaalsContact O-CB 3.28Å; R236-F240 WeakPolarHBondContact O-CB 3.24Å; R236-F240 PolarHBondContact O-N 3.37Å
237	D	57.3	Low	45.9	Very low	92 Å²	92	118.5 Å²	118.5	49%	0.492	57%	0.573	S	S	.	*	H	α-helix	trans	-73.6	-39	178.1	-60	-31.5	0	0	0	109.5	R234 F240 L241	R234-D237 PolarHBondContact O-N 3.07Å; D237-F240 PolarHBondContact O-N 3.29Å; D237-L241 VanDerWaalsContact O-CB 3.26Å; D237-L241 WeakPolarHBondContact O-CB 3.17Å; D237-L241 WeakPolarHBondContact O-CG 3.22Å; D237-L241 PolarHBondContact O-N 3.22Å
238	F	51.3	Low	46.6	Very low	79 Å²	79	113 Å²	113	35%	0.346	54%	0.543	S	S	.	.	H	α-helix	trans	-61.7	-46.2	173.4	-179.1	-96.8	0	0	0	113	V197 R234 L241 L242	V197-F238 HydrophobicContact CG1-CD2 4.41Å; V197-F238 HydrophobicContact CG1-CE2 3.27Å; V197-F238 HydrophobicContact CG1-CZ 3.45Å; V197-F238 VanDerWaalsContact CG1-CZ 3.45Å; R234-F238 PolarHBondContact O-N 3.01Å; F238-L241 PolarHBondContact O-N 3.42Å; F238-L242 HydrophobicContact CE1-CD1 4.2Å; F238-L242 HydrophobicContact CZ-CD1 4.2Å; F238-L242 WeakPolarHBondContact O-CB 3.5Å; F238-L242 PolarHBondContact O-N 2.9Å
239	L	59.1	Low	47.2	Very low	106 Å²	106	108.9 Å²	108.9	56%	0.555	51%	0.508	S	S	*	.	H	α-helix	trans	-69.3	-34.5	178.3	-77.8	172.4	0	0	0	112.6	P235 L242 R243	P235-L239 WeakPolarHBondContact O-CB 3.47Å; P235-L239 WeakPolarHBondContact O-CG 3.22Å; P235-L239 PolarHBondContact O-N 3.41Å; L239-L242 HydrophobicContact CD2-CD2 4.48Å; L239-R243 WeakPolarHBondContact O-CB 3.44Å; L239-R243 PolarHBondContact O-N 3.39Å
240	F	57	Low	48	Very low	121 Å²	121	102.6 Å²	102.6	53%	0.531	48%	0.478	S	S	.	.	H	α-helix	trans	-65.5	-47.9	173.5	-179.4	-94.6	0	0	0	110.7	R236 D237 L242 R243 E244	R236-F240 VanDerWaalsContact O-CB 3.28Å; R236-F240 WeakPolarHBondContact O-CB 3.24Å; R236-F240 PolarHBondContact O-N 3.37Å; D237-F240 PolarHBondContact O-N 3.29Å; F240-L242 PolarHBondContact O-N 2.89Å; F240-R243 WeakPolarHBondContact O-CB 3.45Å; F240-R243 PolarHBondContact O-N 2.86Å; F240-E244 WeakPolarHBondContact CE1-OE2 3.38Å; F240-E244 WeakPolarHBondContact O-CB 3.01Å; F240-E244 PolarHBondContact O-N 2.66Å
241	L	52.2	Low	48.6	Very low	38 Å²	38	99.8 Å²	99.8	20%	0.199	46%	0.458	C	S	.	.	H	α-helix	trans	-63.8	-40.1	175.3	-69.4	175.4	0	0	0	111.9	D237 F238 R243 E244 N245	D237-L241 VanDerWaalsContact O-CB 3.26Å; D237-L241 WeakPolarHBondContact O-CB 3.17Å; D237-L241 WeakPolarHBondContact O-CG 3.22Å; D237-L241 PolarHBondContact O-N 3.22Å; F238-L241 PolarHBondContact O-N 3.42Å; L241-R243 VanDerWaalsContact C-N 3.34Å; L241-E244 PolarHBondContact O-N 3.29Å; L241-N245 WeakPolarHBondContact O-CB 3.25Å; L241-N245 PolarHBondContact O-N 2.97Å; L241-N245 PolarHBondContact O-ND2 3.12Å
242	L	50.8	Low	48.7	Very low	50 Å²	50	92.3 Å²	92.3	26%	0.262	43%	0.427	S	S	.	.	H	α-helix	trans	-62	-44.3	174.1	-166.1	97.9	0	0	0	110	V197 F238 L239 F240 I246	V197-L242 HydrophobicContact CG1-CD1 4.16Å; V197-L242 HydrophobicContact CG2-CD1 3.51Å; F238-L242 HydrophobicContact CE1-CD1 4.2Å; F238-L242 HydrophobicContact CZ-CD1 4.2Å; F238-L242 WeakPolarHBondContact O-CB 3.5Å; F238-L242 PolarHBondContact O-N 2.9Å; L239-L242 HydrophobicContact CD2-CD2 4.48Å; F240-L242 PolarHBondContact O-N 2.89Å; L242-I246 HydrophobicContact CD2-CD1 3.79Å; L242-I246 HydrophobicContact CG-CD1 3.85Å; L242-I246 HydrophobicContact CG-CG1 4.49Å; L242-I246 WeakPolarHBondContact O-CB 3.44Å; L242-I246 WeakPolarHBondContact O-CD1 3.36Å; L242-I246 WeakPolarHBondContact O-CG1 3.3Å; L242-I246 PolarHBondContact O-N 3.44Å
243	R	55.4	Low	49.1	Very low	165 Å²	165	88.7 Å²	88.7	62%	0.623	41%	0.412	S	S	*	.	H	α-helix	trans	-66	-39.9	178	-180	-179.1	-174.2	177.1	2.2	112.3	L239 F240 L241 R247	L239-R243 WeakPolarHBondContact O-CB 3.44Å; L239-R243 PolarHBondContact O-N 3.39Å; F240-R243 WeakPolarHBondContact O-CB 3.45Å; F240-R243 PolarHBondContact O-N 2.86Å; L241-R243 VanDerWaalsContact C-N 3.34Å; R243-R247 WeakPolarHBondContact O-CB 3.4Å; R243-R247 PolarHBondContact O-N 2.96Å
244	E	53.7	Low	49	Very low	84 Å²	84	83.9 Å²	83.9	39%	0.393	40%	0.395	S	S	.	.	H	α-helix	trans	-71.9	-41.8	178.7	-161.9	167.4	-149.2	0	0	110.6	F240 L241 R247 E248	F240-E244 WeakPolarHBondContact CE1-OE2 3.38Å; F240-E244 WeakPolarHBondContact O-CB 3.01Å; F240-E244 PolarHBondContact O-N 2.66Å; L241-E244 PolarHBondContact O-N 3.29Å; E244-R247 CarbonylContact O-C 3.48Å; E244-R247 WeakPolarHBondContact O-CA 3.07Å; E244-R247 WeakPolarHBondContact O-CB 3.01Å; E244-R247 PolarHBondContact O-N 3.22Å; E244-E248 WeakPolarHBondContact O-CG 3.32Å; E244-E248 PolarHBondContact O-N 2.73Å
245	N	50.8	Low	49.1	Very low	31 Å²	31	83.6 Å²	83.6	17%	0.166	40%	0.401	C	S	.	.	H	α-helix	trans	-70.8	-37.1	174.4	-80.7	-88	0	0	0	112.9	Y196 L241 R247 E248 Q249	Y196-N245 HydrophobicContact CE1-CB 4.25Å; L241-N245 WeakPolarHBondContact O-CB 3.25Å; L241-N245 PolarHBondContact O-N 2.97Å; L241-N245 PolarHBondContact O-ND2 3.12Å; N245-R247 VanDerWaalsContact C-N 3.31Å; N245-E248 PolarHBondContact O-N 3.36Å; N245-Q249 WeakPolarHBondContact O-CB 3.33Å; N245-Q249 VanDerWaalsContact O-CG 3.3Å; N245-Q249 WeakPolarHBondContact O-CG 3.43Å; N245-Q249 PolarHBondContact O-N 3.01Å
246	I	52.1	Low	49	Very low	67 Å²	67	83.6 Å²	83.6	34%	0.344	39%	0.394	S	S	.	.	H	α-helix	trans	-57.7	-50.7	167.5	-82.2	171.2	0	0	0	107.7	L242 E248 Q249 F250	L242-I246 HydrophobicContact CD2-CD1 3.79Å; L242-I246 HydrophobicContact CG-CD1 3.85Å; L242-I246 HydrophobicContact CG-CG1 4.49Å; L242-I246 WeakPolarHBondContact O-CB 3.44Å; L242-I246 WeakPolarHBondContact O-CD1 3.36Å; L242-I246 WeakPolarHBondContact O-CG1 3.3Å; L242-I246 PolarHBondContact O-N 3.44Å; I246-E248 VanDerWaalsContact C-N 3.26Å; I246-E248 PolarHBondContact O-N 2.86Å; I246-Q249 CarbonylContact O-C 3.59Å; I246-Q249 WeakPolarHBondContact O-CB 3.47Å; I246-Q249 PolarHBondContact O-N 3.4Å; I246-Q249 VanDerWaalsContact O-N 3.12Å; I246-F250 HydrophobicContact CB-CD2 4.38Å; I246-F250 HydrophobicContact CB-CE2 4.33Å; I246-F250 HydrophobicContact CG2-CD2 3.58Å; I246-F250 HydrophobicContact CG2-CE2 3.54Å; I246-F250 WeakPolarHBondContact O-CB 3.48Å; I246-F250 WeakPolarHBondContact O-CD2 3.47Å; I246-F250 WeakPolarHBondContact O-CG 3.42Å; I246-F250 PolarHBondContact O-N 2.83Å
247	R	49.5	Very low	49	Very low	143 Å²	143	75.3 Å²	75.3	54%	0.54	37%	0.368	S	S	.	.	H	α-helix	trans	-57.9	-37.1	176.5	176	175	-68.4	-159.3	-5.4	112.6	R243 E244 N245 F250 S251	R243-R247 WeakPolarHBondContact O-CB 3.4Å; R243-R247 PolarHBondContact O-N 2.96Å; E244-R247 CarbonylContact O-C 3.48Å; E244-R247 WeakPolarHBondContact O-CA 3.07Å; E244-R247 WeakPolarHBondContact O-CB 3.01Å; E244-R247 PolarHBondContact O-N 3.22Å; N245-R247 VanDerWaalsContact C-N 3.31Å; R247-F250 CarbonylContact O-C 3.58Å; R247-F250 PolarHBondContact O-N 2.87Å; R247-S251 WeakPolarHBondContact O-CB 3.48Å; R247-S251 PolarHBondContact O-N 3.49Å; R247-S251 PolarHBondContact O-OG 3.04Å
248	E	50.2	Low	48.3	Very low	66 Å²	66	76.3 Å²	76.3	31%	0.308	38%	0.378	S	S	.	.	H	α-helix	trans	-69	-43.3	173.4	-72.1	-165.4	151	0	0	112.6	E244 N245 I246 F250 S251 R286	E244-E248 WeakPolarHBondContact O-CG 3.32Å; E244-E248 PolarHBondContact O-N 2.73Å; N245-E248 PolarHBondContact O-N 3.36Å; I246-E248 VanDerWaalsContact C-N 3.26Å; I246-E248 PolarHBondContact O-N 2.86Å; E248-F250 PolarHBondContact O-N 3.03Å; E248-S251 WeakPolarHBondContact CA-OG 3.25Å; E248-S251 PolarHBondContact O-N 2.58Å; E248-S251 PolarHBondContact O-OG 3.41Å; E248-R286 IonicContact OE1-NH1 3.05Å; E248-R286 PolarHBondContact OE1-NH1 3.13Å
249	Q	46.9	Very low	48.2	Very low	6 Å²	6	74.1 Å²	74.1	3%	0.028	37%	0.368	C	S	.	.	H	α-helix	trans	-60.3	-26.3	172.1	-75	-176.7	-26.4	0	0	113	Y196 N245 I246 F293	Y196-Q249 VanDerWaalsContact CE1-CD 3.5Å; Y196-Q249 HydrophobicContact CE1-CG 3.98Å; Y196-Q249 WeakPolarHBondContact OH-CG 3.49Å; N245-Q249 WeakPolarHBondContact O-CB 3.33Å; N245-Q249 VanDerWaalsContact O-CG 3.3Å; N245-Q249 WeakPolarHBondContact O-CG 3.43Å; N245-Q249 PolarHBondContact O-N 3.01Å; I246-Q249 CarbonylContact O-C 3.59Å; I246-Q249 WeakPolarHBondContact O-CB 3.47Å; I246-Q249 PolarHBondContact O-N 3.4Å; I246-Q249 VanDerWaalsContact O-N 3.12Å; Q249-F293 HydrophobicContact CG-CE1 4.48Å
250	F	47.1	Very low	47.3	Very low	48 Å²	48	74.3 Å²	74.3	21%	0.211	37%	0.374	C	S	.	.	H	α-helix	trans	-94.4	-22.6	178.5	-71.3	-65.5	0	0	0	112.4	R131 W135 I246 R247 E248	R131-F250 HydrophobicContact CB-CE1 4.08Å; R131-F250 HydrophobicContact CG-CE1 3.87Å; W135-F250 HydrophobicContact CB-CD1 4.42Å; W135-F250 HydrophobicContact CD2-CB 3.75Å; W135-F250 HydrophobicContact CD2-CG 4.45Å; W135-F250 HydrophobicContact CE3-CB 4.12Å; W135-F250 HydrophobicContact CE3-CG 4.43Å; W135-F250 HydrophobicContact CG-CB 3.99Å; W135-F250 HydrophobicContact CZ2-CB 4.3Å; W135-F250 PolarHBondContact NE1-O 3.3Å; I246-F250 HydrophobicContact CB-CD2 4.38Å; I246-F250 HydrophobicContact CB-CE2 4.33Å; I246-F250 HydrophobicContact CG2-CD2 3.58Å; I246-F250 HydrophobicContact CG2-CE2 3.54Å; I246-F250 WeakPolarHBondContact O-CB 3.48Å; I246-F250 WeakPolarHBondContact O-CD2 3.47Å; I246-F250 WeakPolarHBondContact O-CG 3.42Å; I246-F250 PolarHBondContact O-N 2.83Å; R247-F250 CarbonylContact O-C 3.58Å; R247-F250 PolarHBondContact O-N 2.87Å; E248-F250 PolarHBondContact O-N 3.03Å
251	S	40.2	Very low	46.7	Very low	45 Å²	45	71 Å²	71	32%	0.315	37%	0.366	S	S	.	.	P	Polyproline II helix	trans	-76.3	130	-174.9	53	0	0	0	0	114.2	R247 E248	R247-S251 WeakPolarHBondContact O-CB 3.48Å; R247-S251 PolarHBondContact O-N 3.49Å; R247-S251 PolarHBondContact O-OG 3.04Å; E248-S251 WeakPolarHBondContact CA-OG 3.25Å; E248-S251 PolarHBondContact O-N 2.58Å; E248-S251 PolarHBondContact O-OG 3.41Å
252	S	38.6	Very low	46.2	Very low	35 Å²	35	71.9 Å²	71.9	25%	0.245	37%	0.374	C	S	.	.	P	Polyproline II helix	trans	-61.6	160.7	157.3	-44.1	0	0	0	0	110.1
253	P	43.1	Very low	45.6	Very low	65 Å²	65	78.5 Å²	78.5	42%	0.422	40%	0.403	S	S	.	.	P	Polyproline II helix	trans	-58.1	142.5	-150.2	22.2	-32.1	0	0	0	112.9	H255	P253-H255 PolarHBondContact O-N 3.11Å
254	P	40.5	Very low	44.9	Very low	42 Å²	42	78.1 Å²	78.1	27%	0.273	41%	0.408	S	S	.	.	P	Polyproline II helix	trans	-55.8	140.4	176	24.4	-32.4	0	0	0	109.5	M256 R286	P254-M256 PolarHBondContact O-N 3.39Å; P254-M256 VanDerWaalsContact O-N 3.14Å; P254-R286 VanDerWaalsContact CG-NH2 3.26Å
255	H	43.1	Very low	44.5	Very low	173 Å²	173	81.3 Å²	81.3	80%	0.801	43%	0.426	S	S	*	.			trans	-37.5	119.5	177.4	-163.1	-82.7	0	0	0	109.8	P253 P257	P253-H255 PolarHBondContact O-N 3.11Å; H255-P257 WeakPolarHBondContact O-CD 3.3Å; H255-P257 VanDerWaalsContact O-N 3.13Å
256	M	43.9	Very low	44	Very low	87 Å²	87	88.3 Å²	88.3	43%	0.429	46%	0.457	S	S	.	.	P	Polyproline II helix	trans	-59.5	121.3	-173.4	-168.6	156.9	70.8	0	0	108.3	P254 T258 S344	P254-M256 PolarHBondContact O-N 3.39Å; P254-M256 VanDerWaalsContact O-N 3.14Å; M256-T258 PolarHBondContact O-N 2.83Å; M256-T258 VanDerWaalsContact O-N 3.08Å; M256-S344 PolarHBondContact SD-OG 2.88Å
257	P	45.8	Very low	43.3	Very low	39 Å²	39	89.1 Å²	89.1	25%	0.253	47%	0.469	S	S	.	.	P	Polyproline II helix	trans	-57.2	122.1	174.1	16.5	-24.3	0	0	0	107.3	H255 H259 L280 L348	H255-P257 WeakPolarHBondContact O-CD 3.3Å; H255-P257 VanDerWaalsContact O-N 3.13Å; P257-H259 PolarHBondContact O-N 3.25Å; P257-L280 HydrophobicContact CG-CD2 3.98Å; P257-L348 HydrophobicContact CG-CD2 3.98Å; P257-L348 VanDerWaalsContact O-CD2 3.32Å; P257-L348 WeakPolarHBondContact O-CD2 3.37Å
258	T	43.7	Very low	43.3	Very low	112 Å²	112	86.6 Å²	86.6	69%	0.687	47%	0.466	S	S	*	.	P	Polyproline II helix	trans	-81.1	119	-175.9	-56.6	0	0	0	0	107.2	M256 T260	M256-T258 PolarHBondContact O-N 2.83Å; M256-T258 VanDerWaalsContact O-N 3.08Å; T258-T260 PolarHBondContact O-N 2.95Å
259	H	47.5	Very low	43.8	Very low	33 Å²	33	86.8 Å²	86.8	15%	0.153	47%	0.472	C	S	.	.			trans	-61.4	108.8	170	-163.4	-78.3	0	0	0	107.8	P257 C261 E276 L348 H355	P257-H259 PolarHBondContact O-N 3.25Å; H259-C261 VanDerWaalsContact C-N 3.31Å; H259-C261 PolarHBondContact CE1-SG 2.89Å; H259-C261 VanDerWaalsContact ND1-CB 3.27Å; H259-C261 WeakPolarHBondContact ND1-CB 3.36Å; H259-C261 PolarHBondContact ND1-N 3.38Å; H259-C261 PolarHBondContact O-N 3.31Å; H259-E276 IonicContact CD2-OE1 3.29Å; H259-E276 PolarHBondContact CD2-OE1 2.94Å; H259-E276 IonicContact NE2-OE1 2.66Å; H259-L348 HydrophobicContact CB-CD1 3.43Å; H259-L348 VanDerWaalsContact CB-CD1 3.43Å; H259-H355 AromaticContact NE2-CD2 3.94Å
260	T	40.9	Very low	44.8	Very low	110 Å²	110	87.2 Å²	87.2	68%	0.675	48%	0.475	S	S	*	.			trans	-80.6	90.9	168.6	-46.2	0	0	0	0	105.6	T258 P262	T258-T260 PolarHBondContact O-N 2.95Å; T260-P262 WeakPolarHBondContact O-CD 3.38Å
261	C	44.3	Very low	46.2	Very low	53 Å²	53	90 Å²	90	36%	0.358	49%	0.489	S	S	.	.			trans	-97.6	101.3	166.8	-131.1	0	0	0	0	106.8	H259 Q263	H259-C261 VanDerWaalsContact C-N 3.31Å; H259-C261 PolarHBondContact CE1-SG 2.89Å; H259-C261 VanDerWaalsContact ND1-CB 3.27Å; H259-C261 WeakPolarHBondContact ND1-CB 3.36Å; H259-C261 PolarHBondContact ND1-N 3.38Å; H259-C261 PolarHBondContact O-N 3.31Å; C261-Q263 PolarHBondContact O-N 2.92Å
262	P	41.7	Very low	47.9	Very low	56 Å²	56	92.2 Å²	92.2	36%	0.364	50%	0.497	S	S	.	.			trans	-70.2	127.6	170.9	-9.8	26.2	0	0	0	108.1	T260 H264	T260-P262 WeakPolarHBondContact O-CD 3.38Å; P262-H264 PolarHBondContact O-N 2.93Å
263	Q	39.3	Very low	49.6	Very low	188 Å²	188	92 Å²	92	88%	0.879	49%	0.493	S	S	*	.	S	Bend	trans	-68.4	9.5	173.7	-74.3	-172.4	-30.1	0	0	113.6	C261	C261-Q263 PolarHBondContact O-N 2.92Å
264	H	39.4	Very low	51.4	Low	157 Å²	157	89.6 Å²	89.6	73%	0.727	48%	0.475	S	S	*	.	S	Bend	trans	-130	124.3	-175.9	-79.8	-84.8	0	0	0	112	P262 H266	P262-H264 PolarHBondContact O-N 2.93Å; H264-H266 PolarHBondContact O-N 3.26Å
265	I	45.9	Very low	53.2	Low	151 Å²	151	90.3 Å²	90.3	77%	0.774	49%	0.485	S	S	*	.	S	Bend	trans	-39.1	128.2	166	-60.2	162	0	0	0	109.3
266	H	40	Very low	55.1	Low	178 Å²	178	84.5 Å²	84.5	82%	0.824	46%	0.458	S	S	*	.	S	Bend	trans	87.7	71.7	-179.5	-55.5	-77.2	0	0	0	117.6	H264	H264-H266 PolarHBondContact O-N 3.26Å
267	S	37.9	Very low	56.9	Low	84 Å²	84	80.3 Å²	80.3	59%	0.587	44%	0.438	S	S	*	.			trans	-177.4	49.9	146.6	63.3	0	0	0	0	115.6
268	D	48.3	Very low	58.6	Low	90 Å²	90	81.9 Å²	81.9	48%	0.481	44%	0.441	S	S	.	.			trans	-138.8	116.8	161.9	-76.1	-48.1	0	0	0	110.1
269	T	61.2	Low	60.4	Low	71 Å²	71	82.4 Å²	82.4	44%	0.436	44%	0.436	S	S	.	.			trans	-67.1	142.1	167.6	51.2	0	0	0	0	108.2	E271 L272	T269-E271 PolarHBondContact O-N 2.97Å; T269-L272 WeakPolarHBondContact O-CB 3.42Å; T269-L272 PolarHBondContact O-N 3.43Å; T269-L272 WeakPolarHBondContact OG1-CG 3.37Å
270	P	68.9	Low	62.1	Low	14 Å²	14	81 Å²	81	9%	0.091	43%	0.43	C	S	.	.	H	α-helix	trans	-56.5	-18.1	176.8	21.7	-33.2	0	0	0	113.6	R274 E378 V403	P270-R274 WeakPolarHBondContact O-CG 3.29Å; P270-R274 PolarHBondContact O-N 3.49Å; P270-E378 WeakPolarHBondContact CG-O 3.49Å; P270-V403 HydrophobicContact CB-CG1 3.41Å; P270-V403 VanDerWaalsContact CB-CG1 3.41Å; P270-V403 VanDerWaalsContact O-CG1 3.25Å; P270-V403 WeakPolarHBondContact O-CG1 3.1Å
271	E	75.8	Confident	64.1	Low	106 Å²	106	78 Å²	78	50%	0.495	41%	0.408	S	S	.	.	H	α-helix	trans	-68.3	-39.5	172.9	-66.8	166.5	-163.2	0	0	112.5	T269 R274 A275	T269-E271 PolarHBondContact O-N 2.97Å; E271-R274 PolarHBondContact O-N 3.34Å; E271-A275 PolarHBondContact O-N 3.49Å
272	L	75.9	Confident	65.8	Low	93 Å²	93	78.9 Å²	78.9	49%	0.487	41%	0.414	S	S	.	.	H	α-helix	trans	-65.7	-41	177.8	-70.9	169.6	0	0	0	111.8	T269 R274 A275 E276	T269-L272 WeakPolarHBondContact O-CB 3.42Å; T269-L272 PolarHBondContact O-N 3.43Å; T269-L272 WeakPolarHBondContact OG1-CG 3.37Å; L272-R274 VanDerWaalsContact C-N 3.28Å; L272-R274 PolarHBondContact O-N 3.49Å; L272-A275 PolarHBondContact O-N 2.87Å; L272-E276 WeakPolarHBondContact O-CB 3.48Å; L272-E276 PolarHBondContact O-N 3.24Å
273	I	74.7	Confident	67.6	Low	29 Å²	29	77.1 Å²	77.1	15%	0.149	40%	0.401	C	S	.	.	H	α-helix	trans	-62.6	-37.6	176.1	-61.6	172.5	0	0	0	110.8	V277 H355 V403	I273-V277 VanDerWaalsContact O-CG2 3.31Å; I273-V277 WeakPolarHBondContact O-CG2 3.43Å; I273-V277 PolarHBondContact O-N 3.12Å; I273-V277 VanDerWaalsContact O-N 3.1Å; I273-H355 HydrophobicContact CG2-CB 4.24Å; I273-V403 HydrophobicContact CB-CG1 4.48Å; I273-V403 HydrophobicContact CD1-CG2 4.4Å
274	R	79.7	Confident	69.7	Low	15 Å²	15	69 Å²	69	6%	0.057	36%	0.363	C	S	.	.	H	α-helix	trans	-69.2	-43.3	175.3	-68.4	179.1	-163.2	114.2	6.6	111.5	P270 E271 L272 V277 E278 E378 V403	P270-R274 WeakPolarHBondContact O-CG 3.29Å; P270-R274 PolarHBondContact O-N 3.49Å; E271-R274 PolarHBondContact O-N 3.34Å; L272-R274 VanDerWaalsContact C-N 3.28Å; L272-R274 PolarHBondContact O-N 3.49Å; R274-V277 PolarHBondContact O-N 3.27Å; R274-E278 WeakPolarHBondContact O-CG 3.43Å; R274-E278 PolarHBondContact O-N 3.38Å; R274-E378 VanDerWaalsContact CZ-O 3.3Å; R274-E378 PolarHBondContact NH1-O 2.99Å; R274-E378 IonicContact NH1-OE1 3.92Å; R274-E378 PolarHBondContact NH2-O 3.01Å; R274-V403 HydrophobicContact CG-CG1 4.21Å; R274-V403 VanDerWaalsContact CZ-O 3.28Å; R274-V403 PolarHBondContact NE-O 3.16Å; R274-V403 PolarHBondContact NH2-O 3.13Å
275	A	80.1	Confident	71.8	Confident	58 Å²	58	65 Å²	65	48%	0.479	35%	0.347	S	S	.	.	H	α-helix	trans	-61.1	-43.6	176.9	0	0	0	0	0	111.7	E271 L272 V277 E278 E279	E271-A275 PolarHBondContact O-N 3.49Å; L272-A275 PolarHBondContact O-N 2.87Å; A275-V277 PolarHBondContact O-N 2.94Å; A275-E278 PolarHBondContact O-N 2.87Å; A275-E279 PolarHBondContact O-N 3.45Å
276	E	81.9	Confident	73.5	Confident	50 Å²	50	61.7 Å²	61.7	23%	0.234	33%	0.325	C	S	.	.	H	α-helix	trans	-60.4	-45.4	175.2	-175.2	-173.6	-179.1	0	0	111.7	H259 L272 E278 E279 L280	H259-E276 IonicContact CD2-OE1 3.29Å; H259-E276 PolarHBondContact CD2-OE1 2.94Å; H259-E276 IonicContact NE2-OE1 2.66Å; L272-E276 WeakPolarHBondContact O-CB 3.48Å; L272-E276 PolarHBondContact O-N 3.24Å; E276-E278 VanDerWaalsContact C-N 3.33Å; E276-E278 PolarHBondContact O-N 3.45Å; E276-E279 PolarHBondContact O-N 3.05Å; E276-L280 HydrophobicContact CG-CD1 4.05Å; E276-L280 HydrophobicContact CG-CG 4.42Å; E276-L280 WeakPolarHBondContact O-CB 3.34Å; E276-L280 VanDerWaalsContact O-CG 3.29Å; E276-L280 WeakPolarHBondContact O-CG 3.41Å; E276-L280 PolarHBondContact O-N 3.06Å
277	V	81.7	Confident	75.5	Confident	0 Å²	0	53.4 Å²	53.4	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-63	-39.7	177.4	165.3	0	0	0	0	111.8	I273 R274 A275 L280 K281 L356 F414	I273-V277 VanDerWaalsContact O-CG2 3.31Å; I273-V277 WeakPolarHBondContact O-CG2 3.43Å; I273-V277 PolarHBondContact O-N 3.12Å; I273-V277 VanDerWaalsContact O-N 3.1Å; R274-V277 PolarHBondContact O-N 3.27Å; A275-V277 PolarHBondContact O-N 2.94Å; V277-L280 PolarHBondContact O-N 2.91Å; V277-K281 VanDerWaalsContact O-CB 3.24Å; V277-K281 WeakPolarHBondContact O-CB 3.37Å; V277-K281 PolarHBondContact O-N 3.42Å; V277-L356 HydrophobicContact CB-CD2 4.5Å; V277-L356 HydrophobicContact CG1-CD1 4.45Å; V277-L356 HydrophobicContact CG1-CD2 3.73Å; V277-L356 HydrophobicContact CG2-CB 4.19Å; V277-L356 HydrophobicContact CG2-CD1 4.15Å; V277-L356 HydrophobicContact CG2-CD2 4.13Å; V277-L356 HydrophobicContact CG2-CG 4.37Å; V277-F414 HydrophobicContact CG1-CD1 4Å; V277-F414 HydrophobicContact CG1-CE1 4.09Å; V277-F414 HydrophobicContact CG1-CG 4.27Å; V277-F414 HydrophobicContact CG1-CZ 4.44Å; V277-F414 HydrophobicContact CG2-CE1 4.24Å
278	E	82.4	Confident	77.7	Confident	71 Å²	71	51.4 Å²	51.4	33%	0.332	27%	0.269	S	S	.	.	H	α-helix	trans	-65.1	-42.1	176.2	-75.9	-59.8	122.2	0	0	111.8	R274 A275 E276 K281 S282 H411	R274-E278 WeakPolarHBondContact O-CG 3.43Å; R274-E278 PolarHBondContact O-N 3.38Å; A275-E278 PolarHBondContact O-N 2.87Å; E276-E278 VanDerWaalsContact C-N 3.33Å; E276-E278 PolarHBondContact O-N 3.45Å; E278-K281 PolarHBondContact O-N 2.97Å; E278-K281 IonicContact OE1-NZ 2.62Å; E278-K281 PolarHBondContact OE1-NZ 3.35Å; E278-K281 WeakPolarHBondContact OE2-CE 3.17Å; E278-K281 IonicContact OE2-NZ 3.18Å; E278-K281 PolarHBondContact OE2-NZ 2.84Å; E278-S282 WeakPolarHBondContact O-CB 3.48Å; E278-S282 PolarHBondContact O-N 3.05Å; E278-H411 IonicContact OE1-CD2 3.33Å; E278-H411 IonicContact OE1-NE2 3.46Å; E278-H411 PolarHBondContact OE1-NE2 3.32Å
279	E	81.8	Confident	79.2	Confident	123 Å²	123	51.5 Å²	51.5	58%	0.575	27%	0.265	S	S	*	.	H	α-helix	trans	-61.1	-51.2	173.8	-172.1	179.7	173.5	0	0	111	A275 E276 K281 S282 D283	A275-E279 PolarHBondContact O-N 3.45Å; E276-E279 PolarHBondContact O-N 3.05Å; E279-K281 VanDerWaalsContact C-N 3.29Å; E279-K281 PolarHBondContact O-N 3.4Å; E279-S282 PolarHBondContact O-N 2.83Å; E279-S282 VanDerWaalsContact O-N 3.09Å; E279-S282 PolarHBondContact O-OG 3.34Å; E279-D283 PolarHBondContact O-N 2.89Å
280	L	81.5	Confident	80.2	Confident	5 Å²	5	49.6 Å²	49.6	3%	0.026	25%	0.251	C	S	.	.	H	α-helix	trans	-60.8	-36.4	178.3	-72.3	175.2	0	0	0	112.7	P257 E276 V277 F284 Y345 L348 L349 S352 F414	P257-L280 HydrophobicContact CG-CD2 3.98Å; E276-L280 HydrophobicContact CG-CD1 4.05Å; E276-L280 HydrophobicContact CG-CG 4.42Å; E276-L280 WeakPolarHBondContact O-CB 3.34Å; E276-L280 VanDerWaalsContact O-CG 3.29Å; E276-L280 WeakPolarHBondContact O-CG 3.41Å; E276-L280 PolarHBondContact O-N 3.06Å; V277-L280 PolarHBondContact O-N 2.91Å; L280-F284 WeakPolarHBondContact O-CB 3.49Å; L280-F284 PolarHBondContact O-N 3.38Å; L280-Y345 HydrophobicContact CD2-CE2 4.37Å; L280-L348 HydrophobicContact CD1-CG 4.42Å; L280-L348 HydrophobicContact CD2-CD2 3.73Å; L280-L348 HydrophobicContact CD2-CG 4.14Å; L280-L349 HydrophobicContact CB-CD2 3.89Å; L280-L349 HydrophobicContact CD1-CD2 4.3Å; L280-L349 HydrophobicContact CD2-CD2 4.34Å; L280-L349 HydrophobicContact CG-CD2 4.42Å; L280-S352 VanDerWaalsContact CD1-OG 3.28Å; L280-S352 WeakPolarHBondContact CD1-OG 3.22Å; L280-F414 HydrophobicContact CB-CZ 4.49Å
281	K	83.8	Confident	81.1	Confident	47 Å²	47	49 Å²	49	20%	0.204	25%	0.247	C	C	.	.	H	α-helix	trans	-64.8	-45.3	174	-177.4	-176.1	74.1	-167.4	0	110.9	V277 E278 E279 N285 S410 F414	V277-K281 VanDerWaalsContact O-CB 3.24Å; V277-K281 WeakPolarHBondContact O-CB 3.37Å; V277-K281 PolarHBondContact O-N 3.42Å; E278-K281 PolarHBondContact O-N 2.97Å; E278-K281 IonicContact OE1-NZ 2.62Å; E278-K281 PolarHBondContact OE1-NZ 3.35Å; E278-K281 WeakPolarHBondContact OE2-CE 3.17Å; E278-K281 IonicContact OE2-NZ 3.18Å; E278-K281 PolarHBondContact OE2-NZ 2.84Å; E279-K281 VanDerWaalsContact C-N 3.29Å; E279-K281 PolarHBondContact O-N 3.4Å; K281-N285 WeakPolarHBondContact O-CB 3.48Å; K281-N285 VanDerWaalsContact O-CG 3.25Å; K281-N285 PolarHBondContact O-N 2.91Å; K281-N285 PolarHBondContact O-ND2 3.2Å; K281-N285 VanDerWaalsContact O-ND2 3.17Å; K281-S410 PolarHBondContact NZ-OG 2.92Å; K281-F414 HydrophobicContact CB-CD2 4.46Å
282	S	79.4	Confident	81.6	Confident	70 Å²	70	47 Å²	47	49%	0.49	24%	0.24	S	C	.	.	H	α-helix	trans	-63.4	-42.6	178.1	78.7	0	0	0	0	111.4	E278 E279 N285 R286	E278-S282 WeakPolarHBondContact O-CB 3.48Å; E278-S282 PolarHBondContact O-N 3.05Å; E279-S282 PolarHBondContact O-N 2.83Å; E279-S282 VanDerWaalsContact O-N 3.09Å; E279-S282 PolarHBondContact O-OG 3.34Å; S282-N285 PolarHBondContact O-N 2.89Å; S282-R286 WeakPolarHBondContact O-CB 3.32Å; S282-R286 PolarHBondContact O-N 3.35Å
283	D	80.3	Confident	82	Confident	19 Å²	19	44 Å²	44	10%	0.102	22%	0.223	C	C	.	.	H	α-helix	trans	-65.9	-45	177.7	-169.1	52.2	0	0	0	111.5	E279 N285 R286 R287 Y345	E279-D283 PolarHBondContact O-N 2.89Å; D283-N285 PolarHBondContact O-N 2.97Å; D283-R286 WeakPolarHBondContact O-CB 3.33Å; D283-R286 PolarHBondContact O-N 3.38Å; D283-R286 IonicContact OD1-CZ 3.32Å; D283-R286 IonicContact OD1-NE 3.46Å; D283-R286 IonicContact OD1-NH2 3.07Å; D283-R286 PolarHBondContact OD1-NH2 3.46Å; D283-R287 WeakPolarHBondContact O-CG 3.48Å; D283-R287 PolarHBondContact O-N 3.31Å; D283-R287 IonicContact OD1-NE 3.56Å; D283-R287 IonicContact OD2-CZ 3.4Å; D283-R287 IonicContact OD2-NE 3.87Å; D283-R287 PolarHBondContact OD2-NE 3.13Å; D283-R287 IonicContact OD2-NH2 2.63Å; D283-R287 PolarHBondContact OD2-NH2 3.28Å; D283-Y345 PolarHBondContact OD2-OH 2.93Å
284	F	83.1	Confident	82.6	Confident	18 Å²	18	42.8 Å²	42.8	8%	0.079	22%	0.217	C	C	.	.	H	α-helix	trans	-58.5	-45.2	174.6	179.4	-101.8	0	0	0	112.5	L280 R286 R287 I288 L341 Y345 L349 L417 F418 I424	L280-F284 WeakPolarHBondContact O-CB 3.49Å; L280-F284 PolarHBondContact O-N 3.38Å; F284-R286 VanDerWaalsContact C-N 3.33Å; F284-R286 PolarHBondContact O-N 3.46Å; F284-R287 PolarHBondContact O-N 2.96Å; F284-I288 HydrophobicContact CD1-CD1 3.85Å; F284-I288 HydrophobicContact CE1-CD1 3.19Å; F284-I288 HydrophobicContact CE1-CG1 4.24Å; F284-I288 HydrophobicContact CE2-CD1 4.03Å; F284-I288 HydrophobicContact CE2-CG1 4.47Å; F284-I288 HydrophobicContact CZ-CD1 3.31Å; F284-I288 HydrophobicContact CZ-CG1 4.2Å; F284-I288 PolarHBondContact O-N 2.9Å; F284-L341 HydrophobicContact CE2-CD2 3.87Å; F284-Y345 HydrophobicContact CD2-CE1 4.43Å; F284-L349 HydrophobicContact CD2-CD1 4.12Å; F284-L417 HydrophobicContact CE1-CD2 3.84Å; F284-L417 HydrophobicContact CZ-CD2 3.77Å; F284-F418 HydrophobicContact CD1-CZ 4.08Å; F284-F418 HydrophobicContact CD2-CE1 4.26Å; F284-F418 AromaticContact CD2-CZ 3.79Å; F284-F418 HydrophobicContact CD2-CZ 3.79Å; F284-F418 AromaticContact CE1-CZ 3.92Å; F284-F418 HydrophobicContact CE1-CZ 3.92Å; F284-F418 AromaticContact CE2-CE1 3.87Å; F284-F418 HydrophobicContact CE2-CE1 3.87Å; F284-F418 AromaticContact CE2-CZ 3.62Å; F284-F418 HydrophobicContact CE2-CZ 3.62Å; F284-F418 HydrophobicContact CG-CZ 4Å; F284-F418 HydrophobicContact CZ-CE1 4.16Å; F284-F418 AromaticContact CZ-CZ 3.68Å; F284-F418 HydrophobicContact CZ-CZ 3.68Å; F284-I424 HydrophobicContact CE2-CD1 4.37Å; F284-I424 HydrophobicContact CZ-CD1 4.44Å
285	N	83.5	Confident	83.1	Confident	74 Å²	74	42.1 Å²	42.1	40%	0.396	21%	0.214	S	C	.	.	H	α-helix	trans	-64.9	-38.5	177.8	-74.4	-30	0	0	0	111.9	K281 S282 D283 K289	K281-N285 WeakPolarHBondContact O-CB 3.48Å; K281-N285 VanDerWaalsContact O-CG 3.25Å; K281-N285 PolarHBondContact O-N 2.91Å; K281-N285 PolarHBondContact O-ND2 3.2Å; K281-N285 VanDerWaalsContact O-ND2 3.17Å; S282-N285 PolarHBondContact O-N 2.89Å; D283-N285 PolarHBondContact O-N 2.97Å; N285-K289 VanDerWaalsContact O-CG 3.29Å; N285-K289 WeakPolarHBondContact O-CG 3.48Å; N285-K289 PolarHBondContact O-N 3.43Å; N285-K289 VanDerWaalsContact O-N 3.17Å
286	R	80.9	Confident	83.6	Confident	80 Å²	80	43.8 Å²	43.8	30%	0.302	21%	0.214	S	C	.	.	H	α-helix	trans	-62.8	-49.4	175.1	-174.7	176.7	64	106.4	-0.6	111.1	E248 P254 S282 D283 F284 I288 K289 E290	E248-R286 IonicContact OE1-NH1 3.05Å; E248-R286 PolarHBondContact OE1-NH1 3.13Å; P254-R286 VanDerWaalsContact CG-NH2 3.26Å; S282-R286 WeakPolarHBondContact O-CB 3.32Å; S282-R286 PolarHBondContact O-N 3.35Å; D283-R286 WeakPolarHBondContact O-CB 3.33Å; D283-R286 PolarHBondContact O-N 3.38Å; D283-R286 IonicContact OD1-CZ 3.32Å; D283-R286 IonicContact OD1-NE 3.46Å; D283-R286 IonicContact OD1-NH2 3.07Å; D283-R286 PolarHBondContact OD1-NH2 3.46Å; F284-R286 VanDerWaalsContact C-N 3.33Å; F284-R286 PolarHBondContact O-N 3.46Å; R286-I288 PolarHBondContact O-N 2.99Å; R286-K289 PolarHBondContact O-N 3.18Å; R286-E290 PolarHBondContact O-N 3.38Å
287	R	82.7	Confident	84	Confident	4 Å²	4	41.7 Å²	41.7	2%	0.015	21%	0.205	C	C	.	.	H	α-helix	trans	-58.1	-44.1	176.8	-69.8	179.8	-165.8	-132.1	-1.6	112.7	D283 F284 K289 E290 V291 L340	D283-R287 WeakPolarHBondContact O-CG 3.48Å; D283-R287 PolarHBondContact O-N 3.31Å; D283-R287 IonicContact OD1-NE 3.56Å; D283-R287 IonicContact OD2-CZ 3.4Å; D283-R287 IonicContact OD2-NE 3.87Å; D283-R287 PolarHBondContact OD2-NE 3.13Å; D283-R287 IonicContact OD2-NH2 2.63Å; D283-R287 PolarHBondContact OD2-NH2 3.28Å; F284-R287 PolarHBondContact O-N 2.96Å; R287-K289 VanDerWaalsContact C-N 3.35Å; R287-K289 PolarHBondContact O-N 2.97Å; R287-E290 PolarHBondContact O-N 2.91Å; R287-V291 WeakPolarHBondContact O-CG2 3.44Å; R287-V291 PolarHBondContact O-N 3.25Å; R287-L340 HydrophobicContact CB-CD2 3.89Å; R287-L340 HydrophobicContact CG-CD2 4.2Å; R287-L340 PolarHBondContact NH1-O 2.99Å; R287-L340 VanDerWaalsContact NH1-O 3.12Å
288	I	83.4	Confident	84.4	Confident	43 Å²	43	42 Å²	42	22%	0.221	21%	0.207	C	C	.	.	H	α-helix	trans	-61.5	-43.7	177.6	-76.5	-178	0	0	0	111.6	F284 R286 E290 V291 L292 M337	F284-I288 HydrophobicContact CD1-CD1 3.85Å; F284-I288 HydrophobicContact CE1-CD1 3.19Å; F284-I288 HydrophobicContact CE1-CG1 4.24Å; F284-I288 HydrophobicContact CE2-CD1 4.03Å; F284-I288 HydrophobicContact CE2-CG1 4.47Å; F284-I288 HydrophobicContact CZ-CD1 3.31Å; F284-I288 HydrophobicContact CZ-CG1 4.2Å; F284-I288 PolarHBondContact O-N 2.9Å; R286-I288 PolarHBondContact O-N 2.99Å; I288-E290 VanDerWaalsContact C-N 3.33Å; I288-V291 PolarHBondContact O-N 3.2Å; I288-L292 HydrophobicContact CG2-CD1 3.82Å; I288-L292 HydrophobicContact CG2-CG 4.33Å; I288-L292 WeakPolarHBondContact O-CB 3.44Å; I288-L292 WeakPolarHBondContact O-CG 3.49Å; I288-L292 PolarHBondContact O-N 3.25Å; I288-M337 HydrophobicContact CG1-CE 4.21Å
289	K	81.5	Confident	84.9	Confident	92 Å²	92	38.8 Å²	38.8	40%	0.4	19%	0.192	S	C	.	.	H	α-helix	trans	-63.1	-43.8	179.1	-72.4	173.1	-173.1	-174.6	0	111.3	H203 N285 R286 R287 V291 L292 F293	H203-K289 PolarHBondContact CD2-NZ 2.85Å; H203-K289 PolarHBondContact CE1-NZ 3.46Å; H203-K289 PolarHBondContact ND1-NZ 3.11Å; H203-K289 PolarHBondContact NE2-NZ 2.97Å; N285-K289 VanDerWaalsContact O-CG 3.29Å; N285-K289 WeakPolarHBondContact O-CG 3.48Å; N285-K289 PolarHBondContact O-N 3.43Å; N285-K289 VanDerWaalsContact O-N 3.17Å; R286-K289 PolarHBondContact O-N 3.18Å; R287-K289 VanDerWaalsContact C-N 3.35Å; R287-K289 PolarHBondContact O-N 2.97Å; K289-V291 VanDerWaalsContact C-N 3.32Å; K289-V291 PolarHBondContact O-N 2.86Å; K289-L292 PolarHBondContact O-N 3.13Å; K289-F293 WeakPolarHBondContact O-CB 3.25Å; K289-F293 PolarHBondContact O-N 2.91Å
290	E	82.2	Confident	85.4	Confident	31 Å²	31	34.2 Å²	34.2	15%	0.145	17%	0.17	C	C	.	.	H	α-helix	trans	-58.3	-45.1	175.7	-164.5	-163.8	142.1	0	0	111.1	R286 R287 I288 F293 N294	R286-E290 PolarHBondContact O-N 3.38Å; R287-E290 PolarHBondContact O-N 2.91Å; I288-E290 VanDerWaalsContact C-N 3.33Å; E290-F293 PolarHBondContact O-N 3.35Å; E290-N294 VanDerWaalsContact O-CB 3.29Å; E290-N294 WeakPolarHBondContact O-CB 3.18Å; E290-N294 PolarHBondContact O-N 3.42Å; E290-N294 PolarHBondContact O-ND2 2.9Å
291	V	86.6	Confident	85.9	Confident	0 Å²	0	34 Å²	34	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-63.5	-47.4	177.2	172.4	0	0	0	0	112.2	R287 I288 K289 F293 N294 S295 F333 L336 M337 L340	R287-V291 WeakPolarHBondContact O-CG2 3.44Å; R287-V291 PolarHBondContact O-N 3.25Å; I288-V291 PolarHBondContact O-N 3.2Å; K289-V291 VanDerWaalsContact C-N 3.32Å; K289-V291 PolarHBondContact O-N 2.86Å; V291-F293 VanDerWaalsContact C-N 3.27Å; V291-F293 PolarHBondContact O-N 3.32Å; V291-N294 PolarHBondContact O-N 3.07Å; V291-S295 WeakPolarHBondContact O-CB 3.41Å; V291-S295 PolarHBondContact O-N 3.39Å; V291-S295 PolarHBondContact O-OG 2.95Å; V291-S295 VanDerWaalsContact O-OG 3.12Å; V291-F333 HydrophobicContact CG1-CD2 3.66Å; V291-F333 HydrophobicContact CG1-CE2 3.89Å; V291-L336 HydrophobicContact CB-CB 4.49Å; V291-L336 HydrophobicContact CG1-CB 3.69Å; V291-L336 HydrophobicContact CG2-CB 4.26Å; V291-M337 HydrophobicContact CB-SD 3.87Å; V291-M337 HydrophobicContact CG1-CG 3.68Å; V291-M337 HydrophobicContact CG1-SD 3.57Å; V291-M337 VanDerWaalsContact CG1-SD 3.57Å; V291-M337 HydrophobicContact CG2-SD 3.96Å; V291-L340 HydrophobicContact CG2-CB 4.05Å; V291-L340 HydrophobicContact CG2-CD1 3.67Å; V291-L340 HydrophobicContact CG2-CD2 3.45Å; V291-L340 VanDerWaalsContact CG2-CD2 3.45Å; V291-L340 HydrophobicContact CG2-CG 3.88Å
292	L	87	Confident	86.4	Confident	65 Å²	65	31.8 Å²	31.8	34%	0.34	16%	0.159	S	C	.	.	H	α-helix	trans	-59.1	-42.2	178.4	-76.7	170.1	0	0	0	111.1	I288 K289 S295 L296 W329 F333	I288-L292 HydrophobicContact CG2-CD1 3.82Å; I288-L292 HydrophobicContact CG2-CG 4.33Å; I288-L292 WeakPolarHBondContact O-CB 3.44Å; I288-L292 WeakPolarHBondContact O-CG 3.49Å; I288-L292 PolarHBondContact O-N 3.25Å; K289-L292 PolarHBondContact O-N 3.13Å; L292-S295 PolarHBondContact O-OG 3.26Å; L292-S295 VanDerWaalsContact O-OG 3.08Å; L292-L296 VanDerWaalsContact O-CB 3.3Å; L292-L296 WeakPolarHBondContact O-CB 3.31Å; L292-L296 WeakPolarHBondContact O-CD1 3.36Å; L292-L296 WeakPolarHBondContact O-CG 3.33Å; L292-L296 PolarHBondContact O-N 3.39Å; L292-W329 HydrophobicContact CD2-CZ2 4.42Å; L292-F333 HydrophobicContact CD2-CD2 3.87Å; L292-F333 HydrophobicContact CD2-CE2 3.61Å; L292-F333 HydrophobicContact CG-CE2 4.1Å
293	F	84.9	Confident	86.9	Confident	31 Å²	31	28.4 Å²	28.4	14%	0.136	14%	0.135	C	C	.	.	H	α-helix	trans	-66.9	-48.9	176.9	176.5	-100.2	0	0	0	111.8	Y196 Q249 K289 E290 V291 S295 L296 F297	Y196-F293 HydrophobicContact CD1-CZ 4.48Å; Y196-F293 HydrophobicContact CD2-CB 4.43Å; Y196-F293 AromaticContact CD2-CD1 3.72Å; Y196-F293 HydrophobicContact CD2-CD1 3.72Å; Y196-F293 AromaticContact CD2-CD2 3.28Å; Y196-F293 HydrophobicContact CD2-CD2 3.28Å; Y196-F293 AromaticContact CD2-CE1 3.73Å; Y196-F293 HydrophobicContact CD2-CE1 3.73Å; Y196-F293 AromaticContact CD2-CE2 3.26Å; Y196-F293 HydrophobicContact CD2-CE2 3.26Å; Y196-F293 AromaticContact CD2-CG 3.49Å; Y196-F293 HydrophobicContact CD2-CG 3.49Å; Y196-F293 VanDerWaalsContact CD2-CG 3.49Å; Y196-F293 AromaticContact CD2-CZ 3.48Å; Y196-F293 HydrophobicContact CD2-CZ 3.48Å; Y196-F293 VanDerWaalsContact CD2-CZ 3.48Å; Y196-F293 HydrophobicContact CE2-CB 4.25Å; Y196-F293 AromaticContact CE2-CD1 3.58Å; Y196-F293 HydrophobicContact CE2-CD1 3.58Å; Y196-F293 AromaticContact CE2-CD2 3.9Å; Y196-F293 HydrophobicContact CE2-CD2 3.9Å; Y196-F293 AromaticContact CE2-CE1 3.88Å; Y196-F293 HydrophobicContact CE2-CE1 3.88Å; Y196-F293 HydrophobicContact CE2-CE2 4.15Å; Y196-F293 AromaticContact CE2-CG 3.58Å; Y196-F293 HydrophobicContact CE2-CG 3.58Å; Y196-F293 HydrophobicContact CE2-CZ 4.12Å; Y196-F293 HydrophobicContact CG-CD2 4.16Å; Y196-F293 HydrophobicContact CG-CE1 4.18Å; Y196-F293 AromaticContact CG-CE2 3.67Å; Y196-F293 HydrophobicContact CG-CE2 3.67Å; Y196-F293 AromaticContact CG-CZ 3.66Å; Y196-F293 HydrophobicContact CG-CZ 3.66Å; Q249-F293 HydrophobicContact CG-CE1 4.48Å; K289-F293 WeakPolarHBondContact O-CB 3.25Å; K289-F293 PolarHBondContact O-N 2.91Å; E290-F293 PolarHBondContact O-N 3.35Å; V291-F293 VanDerWaalsContact C-N 3.27Å; V291-F293 PolarHBondContact O-N 3.32Å; F293-S295 VanDerWaalsContact C-N 3.32Å; F293-S295 PolarHBondContact O-N 3.5Å; F293-L296 PolarHBondContact O-N 3.31Å; F293-F297 HydrophobicContact CE1-CB 4.36Å; F293-F297 HydrophobicContact CE1-CD2 4.3Å; F293-F297 HydrophobicContact CZ-CB 4.42Å; F293-F297 HydrophobicContact CZ-CD2 4Å; F293-F297 VanDerWaalsContact O-CB 3.29Å; F293-F297 WeakPolarHBondContact O-CB 3.41Å; F293-F297 PolarHBondContact O-N 2.85Å
294	N	85.9	Confident	87.4	Confident	3 Å²	3	31.2 Å²	31.2	2%	0.016	15%	0.147	C	C	.	.	H	α-helix	trans	-64.9	-35.4	-177.9	-79.6	-28.6	0	0	0	112.3	E290 V291 S298 L336	E290-N294 VanDerWaalsContact O-CB 3.29Å; E290-N294 WeakPolarHBondContact O-CB 3.18Å; E290-N294 PolarHBondContact O-N 3.42Å; E290-N294 PolarHBondContact O-ND2 2.9Å; V291-N294 PolarHBondContact O-N 3.07Å; N294-S298 WeakPolarHBondContact O-CB 3.29Å; N294-S298 PolarHBondContact O-N 3.46Å; N294-S298 PolarHBondContact O-OG 3.17Å; N294-L336 HydrophobicContact CB-CD1 3.81Å
295	S	91.2	Very high	87.8	Confident	0 Å²	0	30.3 Å²	30.3	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-70.4	-42.4	174.4	68.7	0	0	0	0	111.8	V291 L292 F293 S298 A299 W329	V291-S295 WeakPolarHBondContact O-CB 3.41Å; V291-S295 PolarHBondContact O-N 3.39Å; V291-S295 PolarHBondContact O-OG 2.95Å; V291-S295 VanDerWaalsContact O-OG 3.12Å; L292-S295 PolarHBondContact O-OG 3.26Å; L292-S295 VanDerWaalsContact O-OG 3.08Å; F293-S295 VanDerWaalsContact C-N 3.32Å; F293-S295 PolarHBondContact O-N 3.5Å; S295-S298 PolarHBondContact O-N 3.3Å; S295-A299 WeakPolarHBondContact O-CB 3.42Å; S295-A299 PolarHBondContact O-N 3.41Å; S295-W329 PolarHBondContact OG-NE1 2.94Å; S295-W329 VanDerWaalsContact OG-NE1 3.16Å
296	L	90.3	Very high	88.1	Confident	93 Å²	93	26.9 Å²	26.9	49%	0.487	12%	0.124	S	C	.	.	H	α-helix	trans	-62.9	-44.1	174.7	-77.9	170.3	0	0	0	111.7	L292 F293 S298 A299 Y300 W329	L292-L296 VanDerWaalsContact O-CB 3.3Å; L292-L296 WeakPolarHBondContact O-CB 3.31Å; L292-L296 WeakPolarHBondContact O-CD1 3.36Å; L292-L296 WeakPolarHBondContact O-CG 3.33Å; L292-L296 PolarHBondContact O-N 3.39Å; F293-L296 PolarHBondContact O-N 3.31Å; L296-S298 VanDerWaalsContact C-N 3.33Å; L296-S298 PolarHBondContact O-N 2.96Å; L296-A299 PolarHBondContact O-N 2.98Å; L296-Y300 VanDerWaalsContact O-CB 3.26Å; L296-Y300 WeakPolarHBondContact O-CB 3.29Å; L296-Y300 PolarHBondContact O-N 3.36Å; L296-W329 HydrophobicContact CD2-CD2 4.4Å; L296-W329 HydrophobicContact CD2-CG 4.35Å; L296-W329 HydrophobicContact CD2-CZ2 4.31Å; L296-W329 VanDerWaalsContact CD2-NE1 3.3Å
297	F	89.8	Confident	88.4	Confident	7 Å²	7	24.5 Å²	24.5	3%	0.031	12%	0.118	C	C	.	.	H	α-helix	trans	-56.7	-49.2	175	-177.2	-82.3	0	0	0	110.3	M128 R131 P192 F193 F293 A299 Y300 Y301	M128-F297 HydrophobicContact CE-CZ 3.75Å; R131-F297 VanDerWaalsContact CZ-CE1 3.43Å; R131-F297 VanDerWaalsContact CZ-CZ 3.43Å; R131-F297 VanDerWaalsContact NH1-CE2 3.3Å; P192-F297 HydrophobicContact CB-CD2 3.75Å; P192-F297 HydrophobicContact CB-CE2 4.12Å; P192-F297 HydrophobicContact CG-CD2 4.48Å; F193-F297 HydrophobicContact CE1-CE2 4.27Å; F193-F297 AromaticContact CE2-CE2 3.96Å; F193-F297 HydrophobicContact CE2-CE2 3.96Å; F193-F297 HydrophobicContact CE2-CZ 4.4Å; F193-F297 AromaticContact CZ-CE2 3.71Å; F193-F297 HydrophobicContact CZ-CE2 3.71Å; F193-F297 HydrophobicContact CZ-CZ 4.07Å; F293-F297 HydrophobicContact CE1-CB 4.36Å; F293-F297 HydrophobicContact CE1-CD2 4.3Å; F293-F297 HydrophobicContact CZ-CB 4.42Å; F293-F297 HydrophobicContact CZ-CD2 4Å; F293-F297 VanDerWaalsContact O-CB 3.29Å; F293-F297 WeakPolarHBondContact O-CB 3.41Å; F293-F297 PolarHBondContact O-N 2.85Å; F297-A299 PolarHBondContact O-N 3.3Å; F297-Y300 WeakPolarHBondContact O-CB 3.36Å; F297-Y300 PolarHBondContact O-N 3.12Å; F297-Y301 AromaticContact CD1-CD2 3.78Å; F297-Y301 HydrophobicContact CD1-CD2 3.78Å; F297-Y301 HydrophobicContact CD1-CE2 4.07Å; F297-Y301 HydrophobicContact CD2-CD2 4.17Å; F297-Y301 AromaticContact CD2-CE2 3.68Å; F297-Y301 HydrophobicContact CD2-CE2 3.68Å; F297-Y301 AromaticContact CE1-CD2 3.43Å; F297-Y301 HydrophobicContact CE1-CD2 3.43Å; F297-Y301 VanDerWaalsContact CE1-CD2 3.43Å; F297-Y301 AromaticContact CE1-CE2 3.56Å; F297-Y301 HydrophobicContact CE1-CE2 3.56Å; F297-Y301 HydrophobicContact CE1-CG 4.37Å; F297-Y301 AromaticContact CE2-CD2 3.89Å; F297-Y301 HydrophobicContact CE2-CD2 3.89Å; F297-Y301 AromaticContact CE2-CE2 3.15Å; F297-Y301 HydrophobicContact CE2-CE2 3.15Å; F297-Y301 AromaticContact CE2-CZ 3.95Å; F297-Y301 HydrophobicContact CG-CD2 4.11Å; F297-Y301 HydrophobicContact CG-CE2 4.1Å; F297-Y301 AromaticContact CZ-CD2 3.46Å; F297-Y301 HydrophobicContact CZ-CD2 3.46Å; F297-Y301 VanDerWaalsContact CZ-CD2 3.46Å; F297-Y301 AromaticContact CZ-CE2 3.03Å; F297-Y301 HydrophobicContact CZ-CE2 3.03Å; F297-Y301 HydrophobicContact CZ-CG 4.5Å; F297-Y301 AromaticContact CZ-CZ 3.77Å; F297-Y301 VanDerWaalsContact O-CD2 3.3Å; F297-Y301 WeakPolarHBondContact O-CD2 3.46Å; F297-Y301 PolarHBondContact O-N 3Å; F297-Y301 VanDerWaalsContact O-N 3.07Å
298	S	90.6	Very high	88.5	Confident	6 Å²	6	25.8 Å²	25.8	4%	0.042	13%	0.127	C	C	.	.	H	α-helix	trans	-61.3	-46.4	179.9	-56.4	0	0	0	0	111.8	N294 S295 L296 Y300 Y301 V302	N294-S298 WeakPolarHBondContact O-CB 3.29Å; N294-S298 PolarHBondContact O-N 3.46Å; N294-S298 PolarHBondContact O-OG 3.17Å; S295-S298 PolarHBondContact O-N 3.3Å; L296-S298 VanDerWaalsContact C-N 3.33Å; L296-S298 PolarHBondContact O-N 2.96Å; S298-Y300 VanDerWaalsContact C-N 3.33Å; S298-Y300 PolarHBondContact O-N 3.45Å; S298-Y301 PolarHBondContact O-N 3.49Å; S298-V302 VanDerWaalsContact O-CB 3.27Å; S298-V302 WeakPolarHBondContact O-CB 3.38Å; S298-V302 VanDerWaalsContact O-CG2 3.25Å; S298-V302 WeakPolarHBondContact O-CG2 3.29Å; S298-V302 PolarHBondContact O-N 3.2Å
299	A	93	Very high	88.5	Confident	3 Å²	3	24.5 Å²	24.5	3%	0.025	12%	0.12	C	C	.	.	H	α-helix	trans	-64.3	-37	177	0	0	0	0	0	112.7	S295 L296 F297 A303 F304 L325 V328 W329	S295-A299 WeakPolarHBondContact O-CB 3.42Å; S295-A299 PolarHBondContact O-N 3.41Å; L296-A299 PolarHBondContact O-N 2.98Å; F297-A299 PolarHBondContact O-N 3.3Å; A299-A303 WeakPolarHBondContact O-CB 3.21Å; A299-A303 PolarHBondContact O-N 3.37Å; A299-F304 PolarHBondContact O-N 2.99Å; A299-L325 HydrophobicContact CB-CD1 4.04Å; A299-L325 WeakPolarHBondContact O-CD1 3.44Å; A299-V328 HydrophobicContact CB-CG1 4.43Å; A299-W329 HydrophobicContact CB-CB 3.67Å; A299-W329 HydrophobicContact CB-CG 4.31Å
300	Y	92.4	Very high	88.6	Confident	28 Å²	28	21.2 Å²	21.2	11%	0.11	11%	0.107	C	C	.	.	I	π-helix	trans	-60.8	-53.5	177	-177.2	-89.7	0	0	0	111.5	F188 Y191 P192 L296 F297 S298 F304 L305	F188-Y300 WeakPolarHBondContact O-CE1 3.4Å; F188-Y300 PolarHBondContact O-OH 3.43Å; Y191-Y300 AromaticContact CD1-CE2 3.96Å; Y191-Y300 HydrophobicContact CD1-CE2 3.96Å; P192-Y300 HydrophobicContact CG-CD1 3.3Å; P192-Y300 HydrophobicContact CG-CD2 4.28Å; P192-Y300 HydrophobicContact CG-CE1 3.52Å; P192-Y300 HydrophobicContact CG-CE2 4.45Å; P192-Y300 HydrophobicContact CG-CG 3.73Å; L296-Y300 VanDerWaalsContact O-CB 3.26Å; L296-Y300 WeakPolarHBondContact O-CB 3.29Å; L296-Y300 PolarHBondContact O-N 3.36Å; F297-Y300 WeakPolarHBondContact O-CB 3.36Å; F297-Y300 PolarHBondContact O-N 3.12Å; S298-Y300 VanDerWaalsContact C-N 3.33Å; S298-Y300 PolarHBondContact O-N 3.45Å; Y300-F304 HydrophobicContact CD2-CB 4.26Å; Y300-F304 AromaticContact CD2-CD1 3.68Å; Y300-F304 HydrophobicContact CD2-CD1 3.68Å; Y300-F304 HydrophobicContact CD2-CE1 4.4Å; Y300-F304 HydrophobicContact CD2-CG 4.25Å; Y300-F304 AromaticContact CE2-CD1 3.21Å; Y300-F304 HydrophobicContact CE2-CD1 3.21Å; Y300-F304 AromaticContact CE2-CE1 3.57Å; Y300-F304 HydrophobicContact CE2-CE1 3.57Å; Y300-F304 HydrophobicContact CE2-CG 4.18Å; Y300-F304 AromaticContact CZ-CD1 3.69Å; Y300-F304 AromaticContact CZ-CE1 4Å; Y300-F304 WeakPolarHBondContact O-CB 3.38Å; Y300-F304 PolarHBondContact O-N 3.17Å; Y300-F304 VanDerWaalsContact O-N 3.14Å; Y300-L305 HydrophobicContact CE1-CD1 4.14Å; Y300-L305 PolarHBondContact O-N 3.4Å
301	Y	91.6	Very high	88.5	Confident	0 Å²	0	25.6 Å²	25.6	0%	0	13%	0.126	C	C	.	.	I	π-helix	trans	-71.1	-32.3	-178.5	-77.9	-83.2	0	0	0	113.1	F124 I125 L189 P192 F193 F297 S298 L305	F124-Y301 HydrophobicContact CE1-CD1 4.46Å; F124-Y301 AromaticContact CE1-CE1 3.93Å; F124-Y301 HydrophobicContact CE1-CE1 3.93Å; I125-Y301 WeakPolarHBondContact CG2-O 3.35Å; L189-Y301 PolarHBondContact O-OH 2.95Å; P192-Y301 HydrophobicContact CB-CE2 4.33Å; P192-Y301 HydrophobicContact CG-CE2 3.79Å; F193-Y301 WeakPolarHBondContact CE2-OH 3.17Å; F297-Y301 AromaticContact CD1-CD2 3.78Å; F297-Y301 HydrophobicContact CD1-CD2 3.78Å; F297-Y301 HydrophobicContact CD1-CE2 4.07Å; F297-Y301 HydrophobicContact CD2-CD2 4.17Å; F297-Y301 AromaticContact CD2-CE2 3.68Å; F297-Y301 HydrophobicContact CD2-CE2 3.68Å; F297-Y301 AromaticContact CE1-CD2 3.43Å; F297-Y301 HydrophobicContact CE1-CD2 3.43Å; F297-Y301 VanDerWaalsContact CE1-CD2 3.43Å; F297-Y301 AromaticContact CE1-CE2 3.56Å; F297-Y301 HydrophobicContact CE1-CE2 3.56Å; F297-Y301 HydrophobicContact CE1-CG 4.37Å; F297-Y301 AromaticContact CE2-CD2 3.89Å; F297-Y301 HydrophobicContact CE2-CD2 3.89Å; F297-Y301 AromaticContact CE2-CE2 3.15Å; F297-Y301 HydrophobicContact CE2-CE2 3.15Å; F297-Y301 AromaticContact CE2-CZ 3.95Å; F297-Y301 HydrophobicContact CG-CD2 4.11Å; F297-Y301 HydrophobicContact CG-CE2 4.1Å; F297-Y301 AromaticContact CZ-CD2 3.46Å; F297-Y301 HydrophobicContact CZ-CD2 3.46Å; F297-Y301 VanDerWaalsContact CZ-CD2 3.46Å; F297-Y301 AromaticContact CZ-CE2 3.03Å; F297-Y301 HydrophobicContact CZ-CE2 3.03Å; F297-Y301 HydrophobicContact CZ-CG 4.5Å; F297-Y301 AromaticContact CZ-CZ 3.77Å; F297-Y301 VanDerWaalsContact O-CD2 3.3Å; F297-Y301 WeakPolarHBondContact O-CD2 3.46Å; F297-Y301 PolarHBondContact O-N 3Å; F297-Y301 VanDerWaalsContact O-N 3.07Å; S298-Y301 PolarHBondContact O-N 3.49Å; Y301-L305 HydrophobicContact CD1-CD2 3.46Å; Y301-L305 VanDerWaalsContact CD1-CD2 3.46Å; Y301-L305 HydrophobicContact CE1-CD2 3.78Å; Y301-L305 HydrophobicContact CG-CD2 4.49Å
302	V	93.5	Very high	87.6	Confident	0 Å²	0	31.8 Å²	31.8	0%	0	17%	0.17	C	C	.	.	I	π-helix	trans	-79.2	-45.6	-178	169.2	0	0	0	0	112.7	L83 A86 L87 L129 S298 P306 V328	L83-V302 HydrophobicContact CB-CG2 4.18Å; L83-V302 HydrophobicContact CD2-CG2 3.98Å; A86-V302 HydrophobicContact CB-CG1 3.65Å; L87-V302 HydrophobicContact CB-CG1 4.3Å; L129-V302 HydrophobicContact CD1-CG2 3.75Å; L129-V302 HydrophobicContact CD2-CG2 3.83Å; L129-V302 HydrophobicContact CG-CG2 4.45Å; S298-V302 VanDerWaalsContact O-CB 3.27Å; S298-V302 WeakPolarHBondContact O-CB 3.38Å; S298-V302 VanDerWaalsContact O-CG2 3.25Å; S298-V302 WeakPolarHBondContact O-CG2 3.29Å; S298-V302 PolarHBondContact O-N 3.2Å; V302-P306 WeakPolarHBondContact O-CG 3.24Å; V302-V328 HydrophobicContact CB-CG1 4.34Å; V302-V328 HydrophobicContact CG1-CG1 4.08Å
303	A	91.2	Very high	86.7	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	19%	0.19	C	C	.	.	I	π-helix	trans	-111.2	-40.2	-168.5	0	0	0	0	0	113.3	Q90 A299 L307 L325	Q90-A303 PolarHBondContact NE2-O 2.98Å; A299-A303 WeakPolarHBondContact O-CB 3.21Å; A299-A303 PolarHBondContact O-N 3.37Å; A303-L307 VanDerWaalsContact O-CD1 3.3Å; A303-L307 WeakPolarHBondContact O-CD1 3.49Å; A303-L307 WeakPolarHBondContact O-CG 3.37Å; A303-L325 HydrophobicContact CB-CB 3.88Å; A303-L325 HydrophobicContact CB-CD1 3.63Å; A303-L325 HydrophobicContact CB-CG 4.38Å
304	F	90.6	Very high	86.2	Confident	77 Å²	77	35 Å²	35	34%	0.338	19%	0.192	S	C	.	.	I	π-helix	trans	-82.7	-46	-177.4	-177.3	-99.4	0	0	0	112.9	A299 Y300 L307 C308 L325	A299-F304 PolarHBondContact O-N 2.99Å; Y300-F304 HydrophobicContact CD2-CB 4.26Å; Y300-F304 AromaticContact CD2-CD1 3.68Å; Y300-F304 HydrophobicContact CD2-CD1 3.68Å; Y300-F304 HydrophobicContact CD2-CE1 4.4Å; Y300-F304 HydrophobicContact CD2-CG 4.25Å; Y300-F304 AromaticContact CE2-CD1 3.21Å; Y300-F304 HydrophobicContact CE2-CD1 3.21Å; Y300-F304 AromaticContact CE2-CE1 3.57Å; Y300-F304 HydrophobicContact CE2-CE1 3.57Å; Y300-F304 HydrophobicContact CE2-CG 4.18Å; Y300-F304 AromaticContact CZ-CD1 3.69Å; Y300-F304 AromaticContact CZ-CE1 4Å; Y300-F304 WeakPolarHBondContact O-CB 3.38Å; Y300-F304 PolarHBondContact O-N 3.17Å; Y300-F304 VanDerWaalsContact O-N 3.14Å; F304-L307 VanDerWaalsContact O-CB 3.27Å; F304-L307 WeakPolarHBondContact O-CB 3.38Å; F304-L307 PolarHBondContact O-N 3.28Å; F304-C308 WeakPolarHBondContact CE1-SG 3.19Å; F304-C308 PolarHBondContact O-N 2.89Å; F304-L325 HydrophobicContact CB-CD1 4.36Å
305	L	90.6	Very high	85.7	Confident	0 Å²	0	43.6 Å²	43.6	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-61	-42.5	-173.7	-167.8	66.8	0	0	0	113.4	L121 I125 F188 L189 Y300 Y301 L307 C308 F309	L121-L305 HydrophobicContact CD1-CD2 4.14Å; L121-L305 HydrophobicContact CD1-CG 4.33Å; I125-L305 HydrophobicContact CD1-CD2 4.11Å; I125-L305 HydrophobicContact CD1-CG 4.49Å; I125-L305 HydrophobicContact CG1-CD2 3.87Å; F188-L305 HydrophobicContact CB-CD1 4.32Å; L189-L305 HydrophobicContact CD1-CD1 4.07Å; L189-L305 HydrophobicContact CD1-CD2 4.21Å; L189-L305 HydrophobicContact CG-CD2 4.38Å; Y300-L305 HydrophobicContact CE1-CD1 4.14Å; Y300-L305 PolarHBondContact O-N 3.4Å; Y301-L305 HydrophobicContact CD1-CD2 3.46Å; Y301-L305 VanDerWaalsContact CD1-CD2 3.46Å; Y301-L305 HydrophobicContact CE1-CD2 3.78Å; Y301-L305 HydrophobicContact CG-CD2 4.49Å; L305-L307 PolarHBondContact O-N 3.41Å; L305-C308 PolarHBondContact O-N 2.92Å; L305-C308 VanDerWaalsContact O-N 3.17Å; L305-F309 HydrophobicContact CD1-CD2 4.28Å; L305-F309 HydrophobicContact CD1-CE2 3.85Å; L305-F309 HydrophobicContact CG-CD2 4.41Å; L305-F309 HydrophobicContact CG-CE2 4.31Å; L305-F309 WeakPolarHBondContact O-CD2 3.35Å
306	P	89.4	Confident	85.1	Confident	1 Å²	1	46.4 Å²	46.4	1%	0.006	24%	0.236	C	C	.	.	H	α-helix	trans	-57.5	-32.8	174.4	-26.8	37.1	0	0	0	113	L87 Q90 I94 I125 V302 F309 V310	L87-P306 HydrophobicContact CD1-CG 4.04Å; Q90-P306 HydrophobicContact CG-CB 4.24Å; Q90-P306 HydrophobicContact CG-CG 4.26Å; I94-P306 HydrophobicContact CD1-CB 3.78Å; I125-P306 HydrophobicContact CD1-CG 4Å; V302-P306 WeakPolarHBondContact O-CG 3.24Å; P306-F309 PolarHBondContact O-N 2.62Å; P306-V310 VanDerWaalsContact O-CG2 3.29Å; P306-V310 WeakPolarHBondContact O-CG2 3.31Å; P306-V310 PolarHBondContact O-N 2.86Å
307	L	87.7	Confident	84.9	Confident	30 Å²	30	43.6 Å²	43.6	16%	0.157	22%	0.222	C	C	.	.	H	α-helix	trans	-68.7	-35.9	179.6	-60.4	170.5	0	0	0	112.4	I94 A303 F304 L305 F309 V310 Y316	I94-L307 HydrophobicContact CD1-CD2 3.72Å; I94-L307 HydrophobicContact CD1-CG 4.41Å; I94-L307 HydrophobicContact CG1-CD2 3.96Å; A303-L307 VanDerWaalsContact O-CD1 3.3Å; A303-L307 WeakPolarHBondContact O-CD1 3.49Å; A303-L307 WeakPolarHBondContact O-CG 3.37Å; F304-L307 VanDerWaalsContact O-CB 3.27Å; F304-L307 WeakPolarHBondContact O-CB 3.38Å; F304-L307 PolarHBondContact O-N 3.28Å; L305-L307 PolarHBondContact O-N 3.41Å; L307-F309 PolarHBondContact O-N 3.47Å; L307-V310 PolarHBondContact O-N 3.26Å; L307-Y316 HydrophobicContact CD2-CD2 4.08Å; L307-Y316 HydrophobicContact CD2-CE2 3.55Å
308	C	85	Confident	84.6	Confident	32 Å²	32	50 Å²	50	22%	0.216	25%	0.254	C	S	.	.	H	α-helix	trans	-66.2	-26.2	178.2	-64	0	0	0	0	113.1	F188 F304 L305	F188-C308 HydrophobicContact CD2-CB 4.37Å; F304-C308 WeakPolarHBondContact CE1-SG 3.19Å; F304-C308 PolarHBondContact O-N 2.89Å; L305-C308 PolarHBondContact O-N 2.92Å; L305-C308 VanDerWaalsContact O-N 3.17Å
309	F	84.5	Confident	84.5	Confident	15 Å²	15	60.1 Å²	60.1	7%	0.066	29%	0.291	C	S	.	.	T	Hydrogen-bonded Turn	trans	-98.6	5.8	-178.5	-76.2	-97.9	0	0	0	113.2	L121 L177 H181 N185 L189 L305 P306 L307	L121-F309 HydrophobicContact CD1-CD1 4.47Å; L121-F309 HydrophobicContact CD1-CD2 3.98Å; L121-F309 HydrophobicContact CD1-CE2 4.03Å; L121-F309 HydrophobicContact CD1-CG 4.22Å; L121-F309 HydrophobicContact CD1-CZ 4.31Å; L121-F309 HydrophobicContact CD2-CB 3.4Å; L121-F309 HydrophobicContact CD2-CD1 4.12Å; L121-F309 HydrophobicContact CD2-CD2 3.81Å; L121-F309 HydrophobicContact CD2-CG 3.5Å; L121-F309 HydrophobicContact CG-CG 4.46Å; L177-F309 HydrophobicContact CD1-CD1 4.37Å; L177-F309 HydrophobicContact CD1-CE1 3.86Å; L177-F309 HydrophobicContact CD2-CE1 3.97Å; L177-F309 HydrophobicContact CD2-CZ 3.92Å; L177-F309 HydrophobicContact CG-CE1 4.06Å; L177-F309 HydrophobicContact CG-CZ 4.49Å; H181-F309 HydrophobicContact CB-CE1 4.19Å; H181-F309 AromaticContact CD2-CE1 3.91Å; H181-F309 AromaticContact CE1-CD1 3.65Å; H181-F309 AromaticContact CG-CD1 4Å; H181-F309 AromaticContact CG-CE1 3.76Å; H181-F309 AromaticContact ND1-CD1 3.73Å; H181-F309 AromaticContact ND1-CE1 3.95Å; H181-F309 AromaticContact NE2-CD1 3.86Å; N185-F309 HydrophobicContact CB-CE1 3.88Å; N185-F309 HydrophobicContact CB-CZ 3.86Å; N185-F309 WeakPolarHBondContact O-CZ 3.34Å; L189-F309 HydrophobicContact CD1-CE2 3.51Å; L189-F309 HydrophobicContact CD1-CZ 3.37Å; L305-F309 HydrophobicContact CD1-CD2 4.28Å; L305-F309 HydrophobicContact CD1-CE2 3.85Å; L305-F309 HydrophobicContact CG-CD2 4.41Å; L305-F309 HydrophobicContact CG-CE2 4.31Å; L305-F309 WeakPolarHBondContact O-CD2 3.35Å; P306-F309 PolarHBondContact O-N 2.62Å; L307-F309 PolarHBondContact O-N 3.47Å
310	V	83.6	Confident	84.2	Confident	23 Å²	23	61 Å²	61	14%	0.139	29%	0.293	C	S	.	.	S	Bend	trans	-70.7	132.8	174.1	179.3	0	0	0	0	110	I94 P306 L307 Q314 Y316	I94-V310 HydrophobicContact CD1-CG2 4.2Å; I94-V310 HydrophobicContact CG2-CG1 4.38Å; I94-V310 HydrophobicContact CG2-CG2 3.51Å; P306-V310 VanDerWaalsContact O-CG2 3.29Å; P306-V310 WeakPolarHBondContact O-CG2 3.31Å; P306-V310 PolarHBondContact O-N 2.86Å; L307-V310 PolarHBondContact O-N 3.26Å; V310-Q314 HydrophobicContact CG1-CB 3.77Å; V310-Q314 HydrophobicContact CG1-CG 4.18Å; V310-Y316 HydrophobicContact CG1-CD1 4.16Å; V310-Y316 HydrophobicContact CG1-CE1 4.18Å
311	K	78.3	Confident	84	Confident	123 Å²	123	59.8 Å²	59.8	54%	0.535	29%	0.289	S	S	.	.			trans	-63.7	139.3	173.4	-65.3	-177.3	-179.8	178.7	0	109.9	T313 Q314	K311-T313 PolarHBondContact O-N 2.88Å; K311-Q314 PolarHBondContact O-N 2.91Å
312	S	68.6	Low	83.9	Confident	131 Å²	131	62.7 Å²	62.7	92%	0.916	31%	0.309	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.6	-15.4	-178.6	51.8	0	0	0	0	115
313	T	67.3	Low	83.7	Confident	124 Å²	124	66 Å²	66	76%	0.761	32%	0.324	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.5	-9.1	179.1	55.6	0	0	0	0	114.3	K311	K311-T313 PolarHBondContact O-N 2.88Å
314	Q	75.6	Confident	83.7	Confident	40 Å²	40	66 Å²	66	19%	0.187	33%	0.325	C	S	.	.			trans	-92.9	117.9	-177.5	-175.3	69.7	5	0	0	111	I94 V310 K311	I94-Q314 PolarHBondContact O-NE2 3.47Å; I94-Q314 VanDerWaalsContact O-NE2 3.09Å; V310-Q314 HydrophobicContact CG1-CB 3.77Å; V310-Q314 HydrophobicContact CG1-CG 4.18Å; K311-Q314 PolarHBondContact O-N 2.91Å
315	Y	74.3	Confident	83.8	Confident	182 Å²	182	64.6 Å²	64.6	71%	0.714	32%	0.32	S	S	*	.			trans	-84.1	117.9	176.6	-173.8	-93.7	0	0	0	111.2
316	Y	80.4	Confident	84	Confident	59 Å²	59	68.7 Å²	68.7	23%	0.231	34%	0.341	C	S	.	.			trans	-130.6	157.2	174.4	70.9	-88.7	0	0	0	111.4	L307 V310 M318	L307-Y316 HydrophobicContact CD2-CD2 4.08Å; L307-Y316 HydrophobicContact CD2-CE2 3.55Å; V310-Y316 HydrophobicContact CG1-CD1 4.16Å; V310-Y316 HydrophobicContact CG1-CE1 4.18Å; Y316-M318 HydrophobicContact CE2-CB 4.3Å; Y316-M318 PolarHBondContact O-N 2.85Å
317	D	84.3	Confident	84.1	Confident	34 Å²	34	69.1 Å²	69.1	18%	0.182	34%	0.343	C	S	.	.			trans	-80.4	100.4	179.7	-65.4	-77.2	0	0	0	110.4	R96 R319 W320 S321 R448	R96-D317 IonicContact CZ-OD2 2.82Å; R96-D317 IonicContact NH1-OD2 2.73Å; R96-D317 PolarHBondContact NH1-OD2 3.32Å; R96-D317 IonicContact NH2-OD2 3.98Å; R96-D317 PolarHBondContact NH2-OD2 3.44Å; D317-R319 VanDerWaalsContact C-N 3.29Å; D317-R319 PolarHBondContact O-N 3.4Å; D317-W320 HydrophobicContact CB-CB 4.04Å; D317-W320 PolarHBondContact O-N 3.03Å; D317-S321 PolarHBondContact O-N 3.46Å; D317-S321 VanDerWaalsContact O-N 3.13Å; D317-S321 PolarHBondContact O-OG 3.34Å; D317-S321 VanDerWaalsContact O-OG 3.08Å; D317-R448 IonicContact OD1-NH1 3.58Å; D317-R448 PolarHBondContact OD1-NH1 3.36Å; D317-R448 IonicContact OD2-CZ 3.85Å; D317-R448 IonicContact OD2-NH1 3.58Å; D317-R448 PolarHBondContact OD2-NH1 2.66Å
318	M	84.8	Confident	84.4	Confident	142 Å²	142	67.7 Å²	67.7	70%	0.7	34%	0.336	S	S	*	.	H	α-helix	trans	-61	-35.7	-178.6	-172.8	171.8	69	0	0	113	Y316 S321 C322	Y316-M318 HydrophobicContact CE2-CB 4.3Å; Y316-M318 PolarHBondContact O-N 2.85Å; M318-S321 PolarHBondContact O-N 2.85Å; M318-C322 WeakPolarHBondContact O-CB 3.32Å; M318-C322 PolarHBondContact O-N 3.45Å
319	R	87.9	Confident	84.8	Confident	218 Å²	218	70.2 Å²	70.2	82%	0.823	34%	0.341	S	S	*	.	H	α-helix	trans	-61.8	-48.6	177.3	-69.4	-176	-175	155.3	1.8	111.6	D317 S321 C322 E323	D317-R319 VanDerWaalsContact C-N 3.29Å; D317-R319 PolarHBondContact O-N 3.4Å; R319-S321 VanDerWaalsContact C-N 3.32Å; R319-S321 PolarHBondContact O-N 3.46Å; R319-C322 WeakPolarHBondContact O-CB 3.41Å; R319-C322 PolarHBondContact O-N 2.86Å; R319-E323 WeakPolarHBondContact O-CG 3.4Å; R319-E323 PolarHBondContact O-N 3.3Å
320	W	86.5	Confident	85.3	Confident	21 Å²	21	71.5 Å²	71.5	8%	0.08	35%	0.348	C	S	.	.	H	α-helix	trans	-63.9	-39.4	179.8	-168.8	-105.1	0	0	0	112.2	N93 D317 C322 E323 H324 H451 S454 L455	N93-W320 PolarHBondContact ND2-NE1 3.33Å; D317-W320 HydrophobicContact CB-CB 4.04Å; D317-W320 PolarHBondContact O-N 3.03Å; W320-C322 VanDerWaalsContact C-N 3.31Å; W320-C322 PolarHBondContact O-N 2.94Å; W320-E323 VanDerWaalsContact CE3-OE2 3.29Å; W320-E323 PolarHBondContact O-N 2.77Å; W320-H324 WeakPolarHBondContact O-CB 3.29Å; W320-H324 PolarHBondContact O-N 3.46Å; W320-H451 AromaticContact CD1-CD2 3.93Å; W320-H451 AromaticContact CD2-CD2 3.97Å; W320-H451 AromaticContact CD2-CE1 3.93Å; W320-H451 AromaticContact CD2-CG 3.94Å; W320-H451 AromaticContact CD2-ND1 3.92Å; W320-H451 AromaticContact CE2-CD2 3.69Å; W320-H451 AromaticContact CE2-CG 3.6Å; W320-H451 AromaticContact CE3-ND1 3.89Å; W320-H451 AromaticContact CG-NE2 3.91Å; W320-H451 HydrophobicContact CH2-CB 3.69Å; W320-H451 AromaticContact CH2-CG 3.9Å; W320-H451 HydrophobicContact CZ2-CB 3.4Å; W320-H451 VanDerWaalsContact CZ2-CB 3.4Å; W320-H451 AromaticContact CZ2-CG 3.59Å; W320-H451 HydrophobicContact CZ3-CB 4.47Å; W320-H451 AromaticContact CZ3-ND1 3.93Å; W320-H451 AromaticContact NE1-CD2 3.67Å; W320-S454 PolarHBondContact NE1-OG 2.75Å; W320-L455 HydrophobicContact CH2-CD1 3.53Å; W320-L455 HydrophobicContact CH2-CD2 4.31Å; W320-L455 HydrophobicContact CH2-CG 3.85Å; W320-L455 HydrophobicContact CZ2-CD1 3.96Å; W320-L455 HydrophobicContact CZ2-CD2 4.3Å; W320-L455 HydrophobicContact CZ2-CG 3.76Å
321	S	87.8	Confident	85.7	Confident	3 Å²	3	70.4 Å²	70.4	2%	0.021	34%	0.341	C	S	.	.	H	α-helix	trans	-65.6	-35.9	176.2	-55.5	0	0	0	0	112	D317 M318 R319 L325	D317-S321 PolarHBondContact O-N 3.46Å; D317-S321 VanDerWaalsContact O-N 3.13Å; D317-S321 PolarHBondContact O-OG 3.34Å; D317-S321 VanDerWaalsContact O-OG 3.08Å; M318-S321 PolarHBondContact O-N 2.85Å; R319-S321 VanDerWaalsContact C-N 3.32Å; R319-S321 PolarHBondContact O-N 3.46Å; S321-L325 WeakPolarHBondContact O-CB 3.11Å; S321-L325 PolarHBondContact O-N 2.98Å
322	C	89.4	Confident	86.4	Confident	62 Å²	62	64.6 Å²	64.6	42%	0.419	32%	0.316	S	S	.	.	H	α-helix	trans	-69.6	-41.9	173.8	-169.8	0	0	0	0	111.9	M318 R319 W320 H324 L325 I326	M318-C322 WeakPolarHBondContact O-CB 3.32Å; M318-C322 PolarHBondContact O-N 3.45Å; R319-C322 WeakPolarHBondContact O-CB 3.41Å; R319-C322 PolarHBondContact O-N 2.86Å; W320-C322 VanDerWaalsContact C-N 3.31Å; W320-C322 PolarHBondContact O-N 2.94Å; C322-H324 VanDerWaalsContact C-N 3.34Å; C322-H324 PolarHBondContact O-N 3.5Å; C322-L325 WeakPolarHBondContact O-CB 3.3Å; C322-L325 PolarHBondContact O-N 2.83Å; C322-I326 WeakPolarHBondContact O-CG1 3.14Å; C322-I326 PolarHBondContact O-N 3Å
323	E	90.5	Very high	87.5	Confident	68 Å²	68	60.2 Å²	60.2	32%	0.318	28%	0.281	S	S	.	.	H	α-helix	trans	-59.7	-45.4	173	-72.4	175.8	168.6	0	0	110.9	R319 W320 L325 I326 M327 Y438	R319-E323 WeakPolarHBondContact O-CG 3.4Å; R319-E323 PolarHBondContact O-N 3.3Å; W320-E323 VanDerWaalsContact CE3-OE2 3.29Å; W320-E323 PolarHBondContact O-N 2.77Å; E323-L325 PolarHBondContact O-N 3.14Å; E323-I326 PolarHBondContact O-N 3.31Å; E323-M327 HydrophobicContact CB-CE 4.36Å; E323-M327 WeakPolarHBondContact O-CB 3.31Å; E323-M327 VanDerWaalsContact O-CG 3.29Å; E323-M327 WeakPolarHBondContact O-CG 3.44Å; E323-M327 PolarHBondContact O-N 3.01Å; E323-Y438 PolarHBondContact OE1-OH 3.48Å; E323-Y438 VanDerWaalsContact OE1-OH 3.13Å; E323-Y438 PolarHBondContact OE2-OH 3.25Å
324	H	91.3	Very high	88.7	Confident	2 Å²	2	54.3 Å²	54.3	1%	0.009	24%	0.244	C	C	.	.	H	α-helix	trans	-59.2	-45	174.1	-175.8	63.9	0	0	0	112.3	A86 Q90 W320 C322 I326 M327 V328 I458	A86-H324 PolarHBondContact O-NE2 2.83Å; Q90-H324 PolarHBondContact OE1-CD2 3.06Å; W320-H324 WeakPolarHBondContact O-CB 3.29Å; W320-H324 PolarHBondContact O-N 3.46Å; C322-H324 VanDerWaalsContact C-N 3.34Å; C322-H324 PolarHBondContact O-N 3.5Å; H324-I326 PolarHBondContact O-N 3.41Å; H324-M327 PolarHBondContact O-N 3.24Å; H324-V328 VanDerWaalsContact CE1-CG2 3.44Å; H324-V328 WeakPolarHBondContact CE1-CG2 3.46Å; H324-V328 WeakPolarHBondContact O-CB 3.3Å; H324-V328 VanDerWaalsContact O-CG2 3.27Å; H324-V328 WeakPolarHBondContact O-CG2 3.25Å; H324-V328 PolarHBondContact O-N 3.13Å; H324-I458 WeakPolarHBondContact CE1-CD1 3.47Å; H324-I458 WeakPolarHBondContact ND1-CD1 3.32Å
325	L	93.3	Very high	89.4	Confident	47 Å²	47	53 Å²	53	25%	0.246	24%	0.238	C	C	.	.	H	α-helix	trans	-56.2	-48.1	175.6	173.7	67.2	0	0	0	112	A299 A303 F304 S321 C322 E323 V328 W329	A299-L325 HydrophobicContact CB-CD1 4.04Å; A299-L325 WeakPolarHBondContact O-CD1 3.44Å; A303-L325 HydrophobicContact CB-CB 3.88Å; A303-L325 HydrophobicContact CB-CD1 3.63Å; A303-L325 HydrophobicContact CB-CG 4.38Å; F304-L325 HydrophobicContact CB-CD1 4.36Å; S321-L325 WeakPolarHBondContact O-CB 3.11Å; S321-L325 PolarHBondContact O-N 2.98Å; C322-L325 WeakPolarHBondContact O-CB 3.3Å; C322-L325 PolarHBondContact O-N 2.83Å; E323-L325 PolarHBondContact O-N 3.14Å; L325-V328 PolarHBondContact O-N 3.29Å; L325-W329 WeakPolarHBondContact O-CB 3.36Å; L325-W329 PolarHBondContact O-N 3.49Å
326	I	93.1	Very high	90.1	Very high	86 Å²	86	44.3 Å²	44.3	44%	0.441	20%	0.204	S	C	.	.	H	α-helix	trans	-65.7	-43.9	-180	-65.3	166.6	0	0	0	110.6	C322 E323 H324 W329 I330	C322-I326 WeakPolarHBondContact O-CG1 3.14Å; C322-I326 PolarHBondContact O-N 3Å; E323-I326 PolarHBondContact O-N 3.31Å; H324-I326 PolarHBondContact O-N 3.41Å; I326-W329 PolarHBondContact O-N 2.99Å; I326-I330 HydrophobicContact CG2-CD1 3.73Å; I326-I330 HydrophobicContact CG2-CG1 4.36Å; I326-I330 WeakPolarHBondContact O-CG1 3.34Å; I326-I330 PolarHBondContact O-N 2.72Å
327	M	91.8	Very high	90.4	Very high	10 Å²	10	42.3 Å²	42.3	5%	0.049	20%	0.197	C	C	.	.	H	α-helix	trans	-61.8	-45	177.7	-73.1	-173.3	-69.5	0	0	111.8	E323 H324 W329 I330 N331 Y438 Q439 L455	E323-M327 HydrophobicContact CB-CE 4.36Å; E323-M327 WeakPolarHBondContact O-CB 3.31Å; E323-M327 VanDerWaalsContact O-CG 3.29Å; E323-M327 WeakPolarHBondContact O-CG 3.44Å; E323-M327 PolarHBondContact O-N 3.01Å; H324-M327 PolarHBondContact O-N 3.24Å; M327-W329 VanDerWaalsContact C-N 3.32Å; M327-W329 PolarHBondContact O-N 3.41Å; M327-I330 PolarHBondContact O-N 3.44Å; M327-N331 PolarHBondContact O-N 3.37Å; M327-Y438 HydrophobicContact SD-CD1 4.07Å; M327-Y438 HydrophobicContact SD-CE1 3.9Å; M327-Q439 HydrophobicContact SD-CG 3.66Å; M327-L455 HydrophobicContact CE-CD2 4.15Å; M327-L455 HydrophobicContact SD-CD2 4.33Å
328	V	93.9	Very high	90.3	Very high	0 Å²	0	41.9 Å²	41.9	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-62.8	-42.3	178.3	172.1	0	0	0	0	111	Y82 A86 A299 V302 H324 L325 A332	Y82-V328 WeakPolarHBondContact OH-CA 3.3Å; A86-V328 HydrophobicContact CB-CG1 4.43Å; A86-V328 HydrophobicContact CB-CG2 3.82Å; A299-V328 HydrophobicContact CB-CG1 4.43Å; V302-V328 HydrophobicContact CB-CG1 4.34Å; V302-V328 HydrophobicContact CG1-CG1 4.08Å; H324-V328 VanDerWaalsContact CE1-CG2 3.44Å; H324-V328 WeakPolarHBondContact CE1-CG2 3.46Å; H324-V328 WeakPolarHBondContact O-CB 3.3Å; H324-V328 VanDerWaalsContact O-CG2 3.27Å; H324-V328 WeakPolarHBondContact O-CG2 3.25Å; H324-V328 PolarHBondContact O-N 3.13Å; L325-V328 PolarHBondContact O-N 3.29Å; V328-A332 WeakPolarHBondContact O-CB 3.32Å; V328-A332 PolarHBondContact O-N 2.82Å
329	W	94.6	Very high	90.1	Very high	85 Å²	85	36.6 Å²	36.6	32%	0.322	17%	0.17	S	C	.	.	H	α-helix	trans	-62.8	-49.2	177.5	178.1	57.6	0	0	0	112.9	L292 S295 L296 A299 L325 I326 M327 A332 F333	L292-W329 HydrophobicContact CD2-CZ2 4.42Å; S295-W329 PolarHBondContact OG-NE1 2.94Å; S295-W329 VanDerWaalsContact OG-NE1 3.16Å; L296-W329 HydrophobicContact CD2-CD2 4.4Å; L296-W329 HydrophobicContact CD2-CG 4.35Å; L296-W329 HydrophobicContact CD2-CZ2 4.31Å; L296-W329 VanDerWaalsContact CD2-NE1 3.3Å; A299-W329 HydrophobicContact CB-CB 3.67Å; A299-W329 HydrophobicContact CB-CG 4.31Å; L325-W329 WeakPolarHBondContact O-CB 3.36Å; L325-W329 PolarHBondContact O-N 3.49Å; I326-W329 PolarHBondContact O-N 2.99Å; M327-W329 VanDerWaalsContact C-N 3.32Å; M327-W329 PolarHBondContact O-N 3.41Å; W329-A332 PolarHBondContact O-N 2.85Å; W329-F333 VanDerWaalsContact O-CB 3.29Å; W329-F333 WeakPolarHBondContact O-CB 3.46Å; W329-F333 PolarHBondContact O-N 3.34Å
330	I	94.1	Very high	89.4	Confident	42 Å²	42	26.8 Å²	26.8	22%	0.215	13%	0.134	C	C	.	.	H	α-helix	trans	-63.2	-46.7	-179.3	-66.2	170.3	0	0	0	110.5	I326 M327 F333 V334 I431 V435	I326-I330 HydrophobicContact CG2-CD1 3.73Å; I326-I330 HydrophobicContact CG2-CG1 4.36Å; I326-I330 WeakPolarHBondContact O-CG1 3.34Å; I326-I330 PolarHBondContact O-N 2.72Å; M327-I330 PolarHBondContact O-N 3.44Å; I330-F333 WeakPolarHBondContact O-CB 3.34Å; I330-F333 PolarHBondContact O-N 2.96Å; I330-V334 HydrophobicContact CG2-CG2 4.38Å; I330-V334 VanDerWaalsContact O-CG2 3.3Å; I330-V334 WeakPolarHBondContact O-CG2 2.87Å; I330-V334 PolarHBondContact O-N 2.86Å; I330-I431 HydrophobicContact CG2-CG2 3.46Å; I330-I431 VanDerWaalsContact CG2-CG2 3.46Å; I330-V435 HydrophobicContact CB-CG2 4.28Å; I330-V435 HydrophobicContact CD1-CG2 4.5Å; I330-V435 HydrophobicContact CG2-CG2 3.6Å
331	N	92.6	Very high	88.7	Confident	0 Å²	0	26.5 Å²	26.5	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-69.4	-39.5	-179.5	-178.8	36.2	0	0	0	112.2	Y82 M327 F333 V334 M335 N462	Y82-N331 WeakPolarHBondContact CE2-ND2 3.18Å; Y82-N331 WeakPolarHBondContact OH-CB 3.47Å; Y82-N331 PolarHBondContact OH-ND2 3.46Å; M327-N331 PolarHBondContact O-N 3.37Å; N331-F333 VanDerWaalsContact C-N 3.28Å; N331-F333 PolarHBondContact O-N 3.49Å; N331-V334 PolarHBondContact O-N 3.39Å; N331-V334 VanDerWaalsContact O-N 3.13Å; N331-M335 WeakPolarHBondContact O-CG 3.45Å; N331-M335 PolarHBondContact O-N 3.02Å; N331-N462 VanDerWaalsContact CG-OD1 3.29Å; N331-N462 PolarHBondContact ND2-OD1 3.29Å
332	A	92.6	Very high	88	Confident	0 Å²	0	27.5 Å²	27.5	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-60.1	-40	172.3	0	0	0	0	0	111.6	Y82 V328 W329 L336	Y82-A332 HydrophobicContact CE1-CB 4.49Å; V328-A332 WeakPolarHBondContact O-CB 3.32Å; V328-A332 PolarHBondContact O-N 2.82Å; W329-A332 PolarHBondContact O-N 2.85Å; A332-L336 VanDerWaalsContact O-CB 3.31Å; A332-L336 WeakPolarHBondContact O-CB 3.41Å; A332-L336 WeakPolarHBondContact O-CD1 3.39Å; A332-L336 WeakPolarHBondContact O-CG 3.45Å; A332-L336 PolarHBondContact O-N 3.28Å
333	F	92.6	Very high	87.2	Confident	40 Å²	40	26 Å²	26	18%	0.175	13%	0.13	C	C	.	.	H	α-helix	trans	-61.2	-45.8	173	172.8	-96.6	0	0	0	111.5	V291 L292 W329 I330 N331 L336 M337	V291-F333 HydrophobicContact CG1-CD2 3.66Å; V291-F333 HydrophobicContact CG1-CE2 3.89Å; L292-F333 HydrophobicContact CD2-CD2 3.87Å; L292-F333 HydrophobicContact CD2-CE2 3.61Å; L292-F333 HydrophobicContact CG-CE2 4.1Å; W329-F333 VanDerWaalsContact O-CB 3.29Å; W329-F333 WeakPolarHBondContact O-CB 3.46Å; W329-F333 PolarHBondContact O-N 3.34Å; I330-F333 WeakPolarHBondContact O-CB 3.34Å; I330-F333 PolarHBondContact O-N 2.96Å; N331-F333 VanDerWaalsContact C-N 3.28Å; N331-F333 PolarHBondContact O-N 3.49Å; F333-L336 PolarHBondContact O-N 3.46Å; F333-M337 HydrophobicContact CD1-CG 4.11Å; F333-M337 HydrophobicContact CD2-CG 4.07Å; F333-M337 HydrophobicContact CE1-CG 3.7Å; F333-M337 HydrophobicContact CE2-CG 3.65Å; F333-M337 HydrophobicContact CE2-SD 3.9Å; F333-M337 HydrophobicContact CG-CG 4.28Å; F333-M337 HydrophobicContact CZ-CE 4.46Å; F333-M337 HydrophobicContact CZ-CG 3.45Å; F333-M337 VanDerWaalsContact CZ-CG 3.45Å; F333-M337 HydrophobicContact CZ-SD 3.92Å; F333-M337 WeakPolarHBondContact O-CB 3.11Å; F333-M337 VanDerWaalsContact O-CG 3.25Å; F333-M337 WeakPolarHBondContact O-CG 3.41Å; F333-M337 PolarHBondContact O-N 3.39Å
334	V	92.2	Very high	86.3	Confident	0 Å²	0	25.1 Å²	25.1	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-62.3	-49.2	179.3	168.5	0	0	0	0	111.7	I330 N331 L336 M337 S338 L428 I431 E432 V465 L469	I330-V334 HydrophobicContact CG2-CG2 4.38Å; I330-V334 VanDerWaalsContact O-CG2 3.3Å; I330-V334 WeakPolarHBondContact O-CG2 2.87Å; I330-V334 PolarHBondContact O-N 2.86Å; N331-V334 PolarHBondContact O-N 3.39Å; N331-V334 VanDerWaalsContact O-N 3.13Å; V334-L336 VanDerWaalsContact C-N 3.32Å; V334-L336 PolarHBondContact O-N 3.15Å; V334-M337 PolarHBondContact O-N 2.9Å; V334-S338 PolarHBondContact O-N 3.12Å; V334-L428 HydrophobicContact CB-CD1 4.08Å; V334-L428 HydrophobicContact CG1-CD1 3.9Å; V334-L428 HydrophobicContact CG1-CD2 4.38Å; V334-L428 HydrophobicContact CG1-CG 3.92Å; V334-L428 HydrophobicContact CG2-CD1 3.84Å; V334-I431 HydrophobicContact CG2-CG2 3.97Å; V334-E432 HydrophobicContact CG1-CB 4.27Å; V334-E432 HydrophobicContact CG1-CG 4.47Å; V334-V465 HydrophobicContact CG1-CG1 3.97Å; V334-L469 HydrophobicContact CG1-CD1 3.77Å
335	M	89.4	Confident	85.7	Confident	11 Å²	11	25 Å²	25	5%	0.054	13%	0.131	C	C	.	.	H	α-helix	trans	-57.3	-46.6	176.9	-70.5	-177.6	73.9	0	0	110.8	F75 L79 Y82 N331 S338 Q339 V465	F75-M335 HydrophobicContact CE2-CB 4.4Å; F75-M335 WeakPolarHBondContact CE2-O 3.31Å; F75-M335 HydrophobicContact CZ-CB 4.33Å; F75-M335 WeakPolarHBondContact CZ-O 3.48Å; L79-M335 HydrophobicContact CB-CE 4.16Å; L79-M335 HydrophobicContact CD1-CB 4.21Å; L79-M335 HydrophobicContact CD1-CE 4.06Å; L79-M335 HydrophobicContact CD1-SD 4.04Å; Y82-M335 HydrophobicContact CD1-SD 3.77Å; Y82-M335 HydrophobicContact CE1-SD 4.36Å; Y82-M335 HydrophobicContact CG-SD 3.94Å; N331-M335 WeakPolarHBondContact O-CG 3.45Å; N331-M335 PolarHBondContact O-N 3.02Å; M335-S338 PolarHBondContact O-N 2.92Å; M335-S338 PolarHBondContact O-OG 2.78Å; M335-Q339 PolarHBondContact O-N 3.28Å; M335-V465 HydrophobicContact CE-CG2 4.34Å; M335-V465 HydrophobicContact CG-CG1 4.14Å; M335-V465 HydrophobicContact CG-CG2 3.71Å; M335-V465 HydrophobicContact SD-CG2 3.96Å
336	L	88.5	Confident	84.9	Confident	0 Å²	0	23.6 Å²	23.6	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-68.6	-42.6	-179.6	-71.4	169.7	0	0	0	113.5	F75 L79 R132 V291 N294 A332 F333 V334 S338 Q339 L340	F75-L336 HydrophobicContact CE1-CD2 4.29Å; F75-L336 HydrophobicContact CZ-CD2 4.32Å; L79-L336 HydrophobicContact CD2-CD2 3.81Å; L79-L336 HydrophobicContact CD2-CG 4.43Å; R132-L336 VanDerWaalsContact CZ-CD2 3.47Å; V291-L336 HydrophobicContact CB-CB 4.49Å; V291-L336 HydrophobicContact CG1-CB 3.69Å; V291-L336 HydrophobicContact CG2-CB 4.26Å; N294-L336 HydrophobicContact CB-CD1 3.81Å; A332-L336 VanDerWaalsContact O-CB 3.31Å; A332-L336 WeakPolarHBondContact O-CB 3.41Å; A332-L336 WeakPolarHBondContact O-CD1 3.39Å; A332-L336 WeakPolarHBondContact O-CG 3.45Å; A332-L336 PolarHBondContact O-N 3.28Å; F333-L336 PolarHBondContact O-N 3.46Å; V334-L336 VanDerWaalsContact C-N 3.32Å; V334-L336 PolarHBondContact O-N 3.15Å; L336-S338 PolarHBondContact O-N 3.26Å; L336-Q339 PolarHBondContact O-N 3.25Å; L336-Q339 VanDerWaalsContact O-N 3.15Å; L336-L340 WeakPolarHBondContact O-CD1 3.3Å; L336-L340 PolarHBondContact O-N 3.21Å; L336-L340 VanDerWaalsContact O-N 3.07Å
337	M	87.1	Confident	84.1	Confident	18 Å²	18	20.1 Å²	20.1	9%	0.089	11%	0.107	C	C	.	.	H	α-helix	trans	-57.9	-37.2	173.7	-76.4	-57.6	-72.1	0	0	111.6	I288 V291 F333 V334 Q339 L341 L428	I288-M337 HydrophobicContact CG1-CE 4.21Å; V291-M337 HydrophobicContact CB-SD 3.87Å; V291-M337 HydrophobicContact CG1-CG 3.68Å; V291-M337 HydrophobicContact CG1-SD 3.57Å; V291-M337 VanDerWaalsContact CG1-SD 3.57Å; V291-M337 HydrophobicContact CG2-SD 3.96Å; F333-M337 HydrophobicContact CD1-CG 4.11Å; F333-M337 HydrophobicContact CD2-CG 4.07Å; F333-M337 HydrophobicContact CE1-CG 3.7Å; F333-M337 HydrophobicContact CE2-CG 3.65Å; F333-M337 HydrophobicContact CE2-SD 3.9Å; F333-M337 HydrophobicContact CG-CG 4.28Å; F333-M337 HydrophobicContact CZ-CE 4.46Å; F333-M337 HydrophobicContact CZ-CG 3.45Å; F333-M337 VanDerWaalsContact CZ-CG 3.45Å; F333-M337 HydrophobicContact CZ-SD 3.92Å; F333-M337 WeakPolarHBondContact O-CB 3.11Å; F333-M337 VanDerWaalsContact O-CG 3.25Å; F333-M337 WeakPolarHBondContact O-CG 3.41Å; F333-M337 PolarHBondContact O-N 3.39Å; V334-M337 PolarHBondContact O-N 2.9Å; M337-Q339 VanDerWaalsContact C-N 3.31Å; M337-Q339 PolarHBondContact O-N 2.78Å; M337-L341 HydrophobicContact CE-CD1 3.52Å; M337-L341 HydrophobicContact CE-CD2 4.23Å; M337-L341 WeakPolarHBondContact O-CD1 3.39Å; M337-L341 PolarHBondContact O-N 3.46Å; M337-L341 VanDerWaalsContact O-N 3.11Å; M337-L341 HydrophobicContact SD-CD1 4.13Å; M337-L428 HydrophobicContact CB-CD1 4.1Å; M337-L428 HydrophobicContact CB-CD2 4.4Å
338	S	83.4	Confident	83.4	Confident	24 Å²	24	20.1 Å²	20.1	17%	0.168	11%	0.107	C	C	.	.	H	α-helix	trans	-66.4	-29.5	179.1	79.8	0	0	0	0	113.8	V334 M335 L336	V334-S338 PolarHBondContact O-N 3.12Å; M335-S338 PolarHBondContact O-N 2.92Å; M335-S338 PolarHBondContact O-OG 2.78Å; L336-S338 PolarHBondContact O-N 3.26Å
339	Q	79.6	Confident	82.8	Confident	31 Å²	31	20.1 Å²	20.1	15%	0.145	11%	0.107	C	C	.	.	H	α-helix	trans	-83.8	-38.9	178	-170.4	-163.8	18.4	0	0	112	F75 E76 M335 L336 M337	F75-Q339 HydrophobicContact CD1-CB 4.1Å; F75-Q339 HydrophobicContact CD1-CG 3.76Å; F75-Q339 HydrophobicContact CD2-CB 4Å; F75-Q339 HydrophobicContact CD2-CG 4.21Å; F75-Q339 HydrophobicContact CE1-CB 3.84Å; F75-Q339 HydrophobicContact CE1-CG 3.94Å; F75-Q339 HydrophobicContact CE2-CB 3.71Å; F75-Q339 HydrophobicContact CE2-CG 4.36Å; F75-Q339 HydrophobicContact CG-CB 4.18Å; F75-Q339 HydrophobicContact CG-CG 3.9Å; F75-Q339 HydrophobicContact CZ-CB 3.62Å; F75-Q339 HydrophobicContact CZ-CG 4.22Å; E76-Q339 PolarHBondContact OE1-NE2 3.2Å; M335-Q339 PolarHBondContact O-N 3.28Å; L336-Q339 PolarHBondContact O-N 3.25Å; L336-Q339 VanDerWaalsContact O-N 3.15Å; M337-Q339 VanDerWaalsContact C-N 3.31Å; M337-Q339 PolarHBondContact O-N 2.78Å
340	L	72.7	Confident	82.2	Confident	13 Å²	13	18 Å²	18	7%	0.068	10%	0.101	C	C	.	.	H	α-helix	trans	-78.5	-22.2	-176.9	-84.6	84.1	0	0	0	113.7	R287 V291 L336 P342	R287-L340 HydrophobicContact CB-CD2 3.89Å; R287-L340 HydrophobicContact CG-CD2 4.2Å; R287-L340 PolarHBondContact NH1-O 2.99Å; R287-L340 VanDerWaalsContact NH1-O 3.12Å; V291-L340 HydrophobicContact CG2-CB 4.05Å; V291-L340 HydrophobicContact CG2-CD1 3.67Å; V291-L340 HydrophobicContact CG2-CD2 3.45Å; V291-L340 VanDerWaalsContact CG2-CD2 3.45Å; V291-L340 HydrophobicContact CG2-CG 3.88Å; L336-L340 WeakPolarHBondContact O-CD1 3.3Å; L336-L340 PolarHBondContact O-N 3.21Å; L336-L340 VanDerWaalsContact O-N 3.07Å; L340-P342 WeakPolarHBondContact O-CD 3.38Å
341	L	72.2	Confident	81.4	Confident	14 Å²	14	18.8 Å²	18.8	7%	0.073	10%	0.101	C	C	.	.	S	Bend	trans	-111.5	69.2	172.5	-70.5	79	0	0	0	110.1	F284 M337 Y345 I424	F284-L341 HydrophobicContact CE2-CD2 3.87Å; M337-L341 HydrophobicContact CE-CD1 3.52Å; M337-L341 HydrophobicContact CE-CD2 4.23Å; M337-L341 WeakPolarHBondContact O-CD1 3.39Å; M337-L341 PolarHBondContact O-N 3.46Å; M337-L341 VanDerWaalsContact O-N 3.11Å; M337-L341 HydrophobicContact SD-CD1 4.13Å; L341-Y345 HydrophobicContact CG-CD1 4.48Å; L341-I424 HydrophobicContact CD2-CD1 4.19Å; L341-I424 HydrophobicContact CD2-CG2 3.82Å
342	P	74.1	Confident	80.8	Confident	25 Å²	25	18.8 Å²	18.8	16%	0.162	10%	0.101	C	C	.	.			trans	-59.6	153.3	173.9	25.9	-32.2	0	0	0	109.9	L69 L340 S344 Y345 C346	L69-P342 HydrophobicContact CD2-CB 4.33Å; L340-P342 WeakPolarHBondContact O-CD 3.38Å; P342-S344 PolarHBondContact O-N 2.75Å; P342-S344 VanDerWaalsContact O-N 3.08Å; P342-Y345 WeakPolarHBondContact O-CB 3.19Å; P342-Y345 PolarHBondContact O-N 2.89Å; P342-C346 PolarHBondContact O-N 3.47Å
343	P	71.6	Confident	80.3	Confident	31 Å²	31	18.8 Å²	18.8	20%	0.201	10%	0.101	C	C	.	.	H	α-helix	trans	-53.6	-32	179.8	-28.2	35.3	0	0	0	113.7	L67 C346 D347	L67-P343 HydrophobicContact CD1-CB 3.94Å; L67-P343 HydrophobicContact CD1-CG 3.99Å; P343-C346 PolarHBondContact O-N 2.72Å; P343-D347 PolarHBondContact O-N 3.46Å
344	S	72.3	Confident	79.6	Confident	48 Å²	48	17.6 Å²	17.6	34%	0.336	10%	0.098	S	C	.	.	H	α-helix	trans	-64.4	-41	174.2	52	0	0	0	0	113.3	M256 P342 D347 L348	M256-S344 PolarHBondContact SD-OG 2.88Å; P342-S344 PolarHBondContact O-N 2.75Å; P342-S344 VanDerWaalsContact O-N 3.08Å; S344-D347 PolarHBondContact O-N 2.9Å; S344-L348 PolarHBondContact O-N 3.33Å
345	Y	77.7	Confident	78.7	Confident	0 Å²	0	19 Å²	19	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-71.4	-36.4	176.2	-176.2	-113.9	0	0	0	111.4	L280 D283 F284 L341 P342 D347 L348 L349	L280-Y345 HydrophobicContact CD2-CE2 4.37Å; D283-Y345 PolarHBondContact OD2-OH 2.93Å; F284-Y345 HydrophobicContact CD2-CE1 4.43Å; L341-Y345 HydrophobicContact CG-CD1 4.48Å; P342-Y345 WeakPolarHBondContact O-CB 3.19Å; P342-Y345 PolarHBondContact O-N 2.89Å; Y345-D347 VanDerWaalsContact C-N 3.27Å; Y345-D347 PolarHBondContact O-N 3.34Å; Y345-L348 HydrophobicContact CD2-CD2 3.88Å; Y345-L348 HydrophobicContact CE2-CD2 4.06Å; Y345-L348 WeakPolarHBondContact O-CB 3.29Å; Y345-L348 PolarHBondContact O-N 3.4Å; Y345-L349 HydrophobicContact CD1-CD1 3.82Å; Y345-L349 HydrophobicContact CE1-CD1 3.45Å; Y345-L349 VanDerWaalsContact CE1-CD1 3.45Å; Y345-L349 HydrophobicContact CE1-CG 4.23Å; Y345-L349 HydrophobicContact CE2-CG 4.46Å; Y345-L349 WeakPolarHBondContact O-CG 3.29Å; Y345-L349 PolarHBondContact O-N 2.94Å
346	C	77.3	Confident	78.2	Confident	18 Å²	18	18.5 Å²	18.5	12%	0.122	10%	0.102	C	C	.	.	H	α-helix	trans	-62.5	-36.7	171.4	-67.2	0	0	0	0	112	P342 P343 H350	P342-C346 PolarHBondContact O-N 3.47Å; P343-C346 PolarHBondContact O-N 2.72Å; C346-H350 VanDerWaalsContact O-CB 3.31Å; C346-H350 WeakPolarHBondContact O-CB 3.25Å; C346-H350 PolarHBondContact O-N 2.82Å
347	D	76.4	Confident	77.7	Confident	12 Å²	12	18.5 Å²	18.5	6%	0.064	10%	0.102	C	C	.	.	H	α-helix	trans	-68.2	-43.1	174.2	-170.3	49.1	0	0	0	111.7	I64 P343 S344 Y345 L349 H350 R351 Y480	I64-D347 HydrophobicContact CD1-CB 3.57Å; I64-D347 WeakPolarHBondContact CD1-OD1 3.07Å; P343-D347 PolarHBondContact O-N 3.46Å; S344-D347 PolarHBondContact O-N 2.9Å; Y345-D347 VanDerWaalsContact C-N 3.27Å; Y345-D347 PolarHBondContact O-N 3.34Å; D347-L349 VanDerWaalsContact C-N 3.35Å; D347-L349 PolarHBondContact O-N 3.35Å; D347-H350 WeakPolarHBondContact O-CB 3.41Å; D347-H350 PolarHBondContact O-N 2.91Å; D347-H350 VanDerWaalsContact O-N 3.1Å; D347-R351 VanDerWaalsContact O-CG 3.3Å; D347-R351 WeakPolarHBondContact O-CG 3.45Å; D347-R351 PolarHBondContact O-N 3.05Å; D347-R351 IonicContact OD1-NE 3.76Å; D347-R351 IonicContact OD2-CZ 3.09Å; D347-R351 IonicContact OD2-NE 2.84Å; D347-R351 PolarHBondContact OD2-NE 2.98Å; D347-R351 IonicContact OD2-NH2 2.69Å; D347-R351 PolarHBondContact OD2-NH2 3.03Å; D347-Y480 PolarHBondContact OD1-OH 2.8Å
348	L	77.8	Confident	77.4	Confident	11 Å²	11	22.3 Å²	22.3	6%	0.058	12%	0.116	C	C	.	.	H	α-helix	trans	-52.9	-51.5	173.1	172.2	67.2	0	0	0	111.7	P257 H259 L280 S344 Y345 H350 R351 S352	P257-L348 HydrophobicContact CG-CD2 3.98Å; P257-L348 VanDerWaalsContact O-CD2 3.32Å; P257-L348 WeakPolarHBondContact O-CD2 3.37Å; H259-L348 HydrophobicContact CB-CD1 3.43Å; H259-L348 VanDerWaalsContact CB-CD1 3.43Å; L280-L348 HydrophobicContact CD1-CG 4.42Å; L280-L348 HydrophobicContact CD2-CD2 3.73Å; L280-L348 HydrophobicContact CD2-CG 4.14Å; S344-L348 PolarHBondContact O-N 3.33Å; Y345-L348 HydrophobicContact CD2-CD2 3.88Å; Y345-L348 HydrophobicContact CE2-CD2 4.06Å; Y345-L348 WeakPolarHBondContact O-CB 3.29Å; Y345-L348 PolarHBondContact O-N 3.4Å; L348-H350 VanDerWaalsContact C-N 3.28Å; L348-H350 PolarHBondContact O-N 3.24Å; L348-R351 PolarHBondContact O-N 2.85Å; L348-S352 PolarHBondContact O-N 3.26Å; L348-S352 PolarHBondContact O-OG 3.37Å
349	L	79.9	Confident	77.3	Confident	0 Å²	0	21.9 Å²	21.9	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-64.5	-33.8	178.2	-68.7	169.9	0	0	0	112.5	L280 F284 Y345 D347 S352 A353 F414 F418	L280-L349 HydrophobicContact CB-CD2 3.89Å; L280-L349 HydrophobicContact CD1-CD2 4.3Å; L280-L349 HydrophobicContact CD2-CD2 4.34Å; L280-L349 HydrophobicContact CG-CD2 4.42Å; F284-L349 HydrophobicContact CD2-CD1 4.12Å; Y345-L349 HydrophobicContact CD1-CD1 3.82Å; Y345-L349 HydrophobicContact CE1-CD1 3.45Å; Y345-L349 VanDerWaalsContact CE1-CD1 3.45Å; Y345-L349 HydrophobicContact CE1-CG 4.23Å; Y345-L349 HydrophobicContact CE2-CG 4.46Å; Y345-L349 WeakPolarHBondContact O-CG 3.29Å; Y345-L349 PolarHBondContact O-N 2.94Å; D347-L349 VanDerWaalsContact C-N 3.35Å; D347-L349 PolarHBondContact O-N 3.35Å; L349-S352 PolarHBondContact O-OG 3.45Å; L349-A353 WeakPolarHBondContact O-CB 3.27Å; L349-A353 PolarHBondContact O-N 3.02Å; L349-F414 HydrophobicContact CD2-CE2 3.89Å; L349-F414 HydrophobicContact CD2-CZ 3.81Å; L349-F418 HydrophobicContact CB-CB 4.31Å; L349-F418 HydrophobicContact CB-CD1 3.68Å; L349-F418 HydrophobicContact CB-CD2 4.5Å; L349-F418 HydrophobicContact CB-CE1 4.08Å; L349-F418 HydrophobicContact CB-CG 3.92Å; L349-F418 HydrophobicContact CD1-CD1 3.94Å; L349-F418 HydrophobicContact CD1-CE1 3.45Å; L349-F418 VanDerWaalsContact CD1-CE1 3.45Å; L349-F418 HydrophobicContact CD1-CZ 3.86Å; L349-F418 HydrophobicContact CD2-CZ 4.47Å; L349-F418 HydrophobicContact CG-CD1 4.37Å; L349-F418 HydrophobicContact CG-CE1 4.27Å
350	H	82.4	Confident	77.3	Confident	39 Å²	39	25.2 Å²	25.2	18%	0.181	13%	0.126	C	C	.	.	H	α-helix	trans	-67.9	-43.6	175.7	177.3	52.6	0	0	0	111.9	C346 D347 L348 A353 A354 F418 H419 P421	C346-H350 VanDerWaalsContact O-CB 3.31Å; C346-H350 WeakPolarHBondContact O-CB 3.25Å; C346-H350 PolarHBondContact O-N 2.82Å; D347-H350 WeakPolarHBondContact O-CB 3.41Å; D347-H350 PolarHBondContact O-N 2.91Å; D347-H350 VanDerWaalsContact O-N 3.1Å; L348-H350 VanDerWaalsContact C-N 3.28Å; L348-H350 PolarHBondContact O-N 3.24Å; H350-A353 PolarHBondContact O-N 3.06Å; H350-A354 WeakPolarHBondContact O-CB 3.3Å; H350-A354 PolarHBondContact O-N 3.16Å; H350-F418 PolarHBondContact ND1-O 3.21Å; H350-H419 PolarHBondContact CE1-O 3.22Å; H350-H419 PolarHBondContact ND1-O 3.39Å; H350-P421 HydrophobicContact CB-CB 4.09Å
351	R	78.3	Confident	77.6	Confident	59 Å²	59	30.3 Å²	30.3	22%	0.223	15%	0.148	C	C	.	.	H	α-helix	trans	-63.9	-47.7	178.2	-67.3	-177.3	-169	-170.8	5.1	111.4	H61 D347 L348 A353 A354 H355	H61-R351 WeakPolarHBondContact ND1-CG 3.44Å; D347-R351 VanDerWaalsContact O-CG 3.3Å; D347-R351 WeakPolarHBondContact O-CG 3.45Å; D347-R351 PolarHBondContact O-N 3.05Å; D347-R351 IonicContact OD1-NE 3.76Å; D347-R351 IonicContact OD2-CZ 3.09Å; D347-R351 IonicContact OD2-NE 2.84Å; D347-R351 PolarHBondContact OD2-NE 2.98Å; D347-R351 IonicContact OD2-NH2 2.69Å; D347-R351 PolarHBondContact OD2-NH2 3.03Å; L348-R351 PolarHBondContact O-N 2.85Å; R351-A353 VanDerWaalsContact C-N 3.33Å; R351-A353 PolarHBondContact O-N 2.97Å; R351-A354 WeakPolarHBondContact O-CB 3.29Å; R351-A354 PolarHBondContact O-N 3.45Å; R351-A354 VanDerWaalsContact O-N 3.14Å; R351-H355 PolarHBondContact O-CD2 3.08Å; R351-H355 PolarHBondContact O-N 3.1Å
352	S	79.3	Confident	77.7	Confident	0 Å²	0	31.3 Å²	31.3	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-64	-38.2	176.8	63.1	0	0	0	0	111.9	L280 L348 L349 A354 H355 L356	L280-S352 VanDerWaalsContact CD1-OG 3.28Å; L280-S352 WeakPolarHBondContact CD1-OG 3.22Å; L348-S352 PolarHBondContact O-N 3.26Å; L348-S352 PolarHBondContact O-OG 3.37Å; L349-S352 PolarHBondContact O-OG 3.45Å; S352-A354 VanDerWaalsContact C-N 3.35Å; S352-A354 PolarHBondContact O-N 3.03Å; S352-H355 PolarHBondContact O-N 3.36Å; S352-L356 WeakPolarHBondContact O-CB 3.45Å; S352-L356 PolarHBondContact O-N 2.96Å
353	A	81.8	Confident	77.7	Confident	0 Å²	0	37.7 Å²	37.7	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-65	-35.2	173	0	0	0	0	0	113.2	L349 H350 R351 L356 G357 F414 Y415 F418	L349-A353 WeakPolarHBondContact O-CB 3.27Å; L349-A353 PolarHBondContact O-N 3.02Å; H350-A353 PolarHBondContact O-N 3.06Å; R351-A353 VanDerWaalsContact C-N 3.33Å; R351-A353 PolarHBondContact O-N 2.97Å; A353-L356 PolarHBondContact O-N 2.93Å; A353-G357 PolarHBondContact O-N 3.26Å; A353-F414 HydrophobicContact CB-CD1 4.11Å; A353-F414 HydrophobicContact CB-CE1 3.82Å; A353-Y415 WeakPolarHBondContact O-CD2 3.47Å; A353-Y415 WeakPolarHBondContact O-CE2 3.2Å; A353-F418 HydrophobicContact CB-CB 3.76Å
354	A	77.4	Confident	76.9	Confident	15 Å²	15	42.5 Å²	42.5	12%	0.124	20%	0.2	C	C	.	.	H	α-helix	trans	-67.9	-37.1	176.3	0	0	0	0	0	112.2	V59 H350 R351 S352	V59-A354 HydrophobicContact CG1-CB 3.99Å; H350-A354 WeakPolarHBondContact O-CB 3.3Å; H350-A354 PolarHBondContact O-N 3.16Å; R351-A354 WeakPolarHBondContact O-CB 3.29Å; R351-A354 PolarHBondContact O-N 3.45Å; R351-A354 VanDerWaalsContact O-N 3.14Å; S352-A354 VanDerWaalsContact C-N 3.35Å; S352-A354 PolarHBondContact O-N 3.03Å
355	H	74.5	Confident	76.3	Confident	30 Å²	30	43.5 Å²	43.5	14%	0.139	22%	0.218	C	C	.	.	H	α-helix	trans	-72.7	-33.7	174.1	-69.1	-56.6	0	0	0	112.9	V59 H61 H259 I273 R351 S352 Y401	V59-H355 WeakPolarHBondContact CG2-ND1 3.45Å; H61-H355 AromaticContact CE1-CE1 3.91Å; H61-H355 AromaticContact CE1-NE2 3.34Å; H61-H355 PolarHBondContact CE1-NE2 3.41Å; H61-H355 VanDerWaalsContact CE1-NE2 3.34Å; H61-H355 AromaticContact NE2-CE1 3.8Å; H61-H355 AromaticContact NE2-NE2 3.29Å; H61-H355 PolarHBondContact NE2-NE2 3.37Å; H259-H355 AromaticContact NE2-CD2 3.94Å; I273-H355 HydrophobicContact CG2-CB 4.24Å; R351-H355 PolarHBondContact O-CD2 3.08Å; R351-H355 PolarHBondContact O-N 3.1Å; S352-H355 PolarHBondContact O-N 3.36Å; H355-Y401 WeakPolarHBondContact O-CB 3.14Å
356	L	78	Confident	75.2	Confident	0 Å²	0	46.7 Å²	46.7	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-69.3	-44.5	-179.9	-176.4	66.7	0	0	0	113.2	V277 S352 A353 N402 V403 A404 H411 F414	V277-L356 HydrophobicContact CB-CD2 4.5Å; V277-L356 HydrophobicContact CG1-CD1 4.45Å; V277-L356 HydrophobicContact CG1-CD2 3.73Å; V277-L356 HydrophobicContact CG2-CB 4.19Å; V277-L356 HydrophobicContact CG2-CD1 4.15Å; V277-L356 HydrophobicContact CG2-CD2 4.13Å; V277-L356 HydrophobicContact CG2-CG 4.37Å; S352-L356 WeakPolarHBondContact O-CB 3.45Å; S352-L356 PolarHBondContact O-N 2.96Å; A353-L356 PolarHBondContact O-N 2.93Å; L356-N402 PolarHBondContact O-OD1 3Å; L356-V403 PolarHBondContact O-N 2.78Å; L356-A404 HydrophobicContact CD1-CB 4Å; L356-A404 HydrophobicContact CG-CB 4.04Å; L356-A404 PolarHBondContact O-N 3.5Å; L356-H411 HydrophobicContact CD2-CB 4.15Å; L356-F414 HydrophobicContact CD2-CD1 3.91Å
357	G	77.9	Confident	74.1	Confident	0 Å²	0	48.9 Å²	48.9	0%	0	25%	0.247	C	C	.	.			trans	73.6	-174.4	-174.6	0	0	0	0	0	114.7	A353 Y401 Y415	A353-G357 PolarHBondContact O-N 3.26Å; G357-Y401 WeakPolarHBondContact CA-O 3.46Å; G357-Y401 PolarHBondContact N-O 3.4Å; G357-Y415 VanDerWaalsContact C-CE2 3.46Å; G357-Y415 VanDerWaalsContact CA-CE2 3.41Å; G357-Y415 WeakPolarHBondContact O-CD2 3.38Å
358	R	81.8	Confident	72.9	Confident	98 Å²	98	53.1 Å²	53.1	37%	0.37	28%	0.277	S	S	.	.			trans	-142.4	143.9	174.3	174	177.2	178.9	-164.3	4.1	111.3	V398 N402 Y415	R358-V398 PolarHBondContact O-N 3.48Å; R358-N402 PolarHBondContact N-OD1 3.23Å; R358-Y415 HydrophobicContact CB-CD1 3.42Å; R358-Y415 VanDerWaalsContact CB-CD1 3.42Å; R358-Y415 HydrophobicContact CB-CD2 4.15Å; R358-Y415 HydrophobicContact CB-CE1 3.7Å; R358-Y415 HydrophobicContact CB-CE2 4.39Å; R358-Y415 HydrophobicContact CB-CG 3.64Å; R358-Y415 HydrophobicContact CG-CD1 4.25Å
359	W	80.1	Confident	71.7	Confident	16 Å²	16	59.5 Å²	59.5	6%	0.061	31%	0.311	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.5	132.7	166	-65.2	100.1	0	0	0	111.7	W382 V388 Y395 A397 N402 A404 P406	W359-W382 HydrophobicContact CH2-CB 3.76Å; W359-W382 AromaticContact CH2-CD1 3.84Å; W359-W382 HydrophobicContact CH2-CD2 4.16Å; W359-W382 AromaticContact CH2-CG 3.6Å; W359-W382 HydrophobicContact CH2-CG 3.6Å; W359-W382 HydrophobicContact CZ2-CB 4.14Å; W359-W382 AromaticContact CZ2-CD1 3.66Å; W359-W382 AromaticContact CZ2-CG 3.89Å; W359-W382 HydrophobicContact CZ2-CG 3.89Å; W359-V388 HydrophobicContact CH2-CB 3.78Å; W359-V388 HydrophobicContact CH2-CG1 4.46Å; W359-V388 HydrophobicContact CH2-CG2 3.43Å; W359-V388 VanDerWaalsContact CH2-CG2 3.43Å; W359-V388 HydrophobicContact CZ3-CB 3.73Å; W359-V388 HydrophobicContact CZ3-CG2 3.67Å; W359-Y395 HydrophobicContact CB-CD1 3.99Å; W359-Y395 HydrophobicContact CB-CG 4.37Å; W359-A397 HydrophobicContact CE3-CB 4.38Å; W359-A397 HydrophobicContact CH2-CB 4.29Å; W359-A397 HydrophobicContact CZ3-CB 3.9Å; W359-N402 VanDerWaalsContact CE3-ND2 3.31Å; W359-N402 WeakPolarHBondContact CH2-ND2 3.32Å; W359-N402 WeakPolarHBondContact CZ2-ND2 3.18Å; W359-N402 WeakPolarHBondContact CZ3-ND2 3.42Å; W359-N402 PolarHBondContact NE1-ND2 3.49Å; W359-N402 PolarHBondContact NE1-OD1 2.77Å; W359-A404 PolarHBondContact NE1-O 2.8Å; W359-P406 HydrophobicContact CB-CB 4.13Å; W359-P406 HydrophobicContact CD2-CB 3.96Å; W359-P406 HydrophobicContact CG-CB 3.66Å
360	Q	79.8	Confident	70.5	Confident	101 Å²	101	61.7 Å²	61.7	47%	0.472	33%	0.325	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.9	117.8	168.3	-176.9	172.4	20.5	0	0	108.9	L362 Y395 K396 V398	Q360-L362 PolarHBondContact O-N 3.36Å; Q360-Y395 CarbonylContact O-C 3.55Å; Q360-Y395 WeakPolarHBondContact O-CA 3.44Å; Q360-K396 PolarHBondContact N-O 3.42Å; Q360-K396 PolarHBondContact O-N 2.93Å; Q360-V398 HydrophobicContact CB-CG2 3.7Å
361	K	79.9	Confident	69	Low	120 Å²	120	66 Å²	66	52%	0.522	36%	0.357	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-66.5	126.3	174.5	-171.1	175.8	179.6	174.6	0	109.3	C393 Y395	K361-C393 WeakPolarHBondContact CE-SG 3.45Å; K361-C393 HydrophobicContact CG-CB 4.48Å; K361-Y395 HydrophobicContact CB-CD1 3.99Å; K361-Y395 HydrophobicContact CB-CE1 3.77Å; K361-Y395 HydrophobicContact CD-CE1 4.37Å; K361-Y395 HydrophobicContact CG-CD1 4.41Å; K361-Y395 HydrophobicContact CG-CE1 3.95Å
362	L	74.3	Confident	68	Low	34 Å²	34	67.4 Å²	67.4	18%	0.178	37%	0.371	C	S	.	.	P	Polyproline II helix	trans	-85.2	137.6	173.6	-128.6	73.5	0	0	0	109.5	Q360 Y367 L387 L394 K396	Q360-L362 PolarHBondContact O-N 3.36Å; L362-Y367 PolarHBondContact O-OH 3.44Å; L362-L387 HydrophobicContact CD2-CD2 4.47Å; L362-L394 HydrophobicContact CB-CB 4.22Å; L362-L394 HydrophobicContact CB-CD2 4.5Å; L362-L394 HydrophobicContact CD2-CD2 3.91Å; L362-L394 PolarHBondContact N-O 2.83Å; L362-K396 HydrophobicContact CD1-CB 4.34Å
363	E	73.3	Confident	67.1	Low	159 Å²	159	70 Å²	70	74%	0.743	39%	0.39	S	S	*	.	P	Polyproline II helix	trans	-76.4	156.6	176.7	-68.9	-172.5	164.7	0	0	112	G365 S366	E363-G365 PolarHBondContact O-N 2.97Å; E363-S366 PolarHBondContact O-N 3.48Å
364	H	56	Low	66.3	Low	132 Å²	132	74.6 Å²	74.6	61%	0.611	41%	0.41	S	S	*	.	G	3₁₀ helix	trans	-66.2	-14.7	-163.3	-64.1	70.2	0	0	0	115.2	Y367	H364-Y367 HydrophobicContact CB-CD2 4.15Å; H364-Y367 HydrophobicContact CB-CE2 3.63Å; H364-Y367 AromaticContact CD2-CE2 3.46Å; H364-Y367 VanDerWaalsContact CD2-CE2 3.46Å; H364-Y367 WeakPolarHBondContact CD2-CE2 3.27Å; H364-Y367 AromaticContact CG-CE2 3.6Å; H364-Y367 WeakPolarHBondContact O-CD2 3.44Å
365	G	58.7	Low	65.7	Low	70 Å²	70	84.5 Å²	84.5	72%	0.722	44%	0.444	S	S	*	.	G	3₁₀ helix	trans	-80.3	-11.9	178.3	0	0	0	0	0	115.4	E363	E363-G365 PolarHBondContact O-N 2.97Å
366	S	54.1	Low	65.7	Low	67 Å²	67	85 Å²	85	47%	0.469	45%	0.445	S	S	.	.	G	3₁₀ helix	trans	-98.8	4.5	-177	-62.9	0	0	0	0	114.3	E363 S368	E363-S366 PolarHBondContact O-N 3.48Å; S366-S368 PolarHBondContact O-N 3.27Å
367	Y	55	Low	65.4	Low	63 Å²	63	86.7 Å²	86.7	25%	0.247	46%	0.457	C	S	.	.	G	3₁₀ helix	trans	-76.1	-18.8	-173.2	-63.6	-39.6	0	0	0	115.1	L362 H364 N369 L394	L362-Y367 PolarHBondContact O-OH 3.44Å; H364-Y367 HydrophobicContact CB-CD2 4.15Å; H364-Y367 HydrophobicContact CB-CE2 3.63Å; H364-Y367 AromaticContact CD2-CE2 3.46Å; H364-Y367 VanDerWaalsContact CD2-CE2 3.46Å; H364-Y367 WeakPolarHBondContact CD2-CE2 3.27Å; H364-Y367 AromaticContact CG-CE2 3.6Å; H364-Y367 WeakPolarHBondContact O-CD2 3.44Å; Y367-N369 PolarHBondContact O-N 3.04Å; Y367-L394 HydrophobicContact CD1-CB 3.88Å; Y367-L394 HydrophobicContact CD1-CD2 4.17Å; Y367-L394 HydrophobicContact CE1-CB 3.38Å; Y367-L394 HydrophobicContact CE1-CD2 4.44Å
368	S	51.9	Low	64.9	Low	101 Å²	101	91.3 Å²	91.3	71%	0.706	48%	0.478	S	S	*	.	G	3₁₀ helix	trans	-77.2	-19.9	-167.9	51	0	0	0	0	114.6	S366	S366-S368 PolarHBondContact O-N 3.27Å
369	N	52	Low	64.1	Low	145 Å²	145	90.8 Å²	90.8	78%	0.775	49%	0.489	S	S	*	.	G	3₁₀ helix	trans	-118.6	13.7	-169.4	-71.4	-23.1	0	0	0	115	Y367 P371	Y367-N369 PolarHBondContact O-N 3.04Å; N369-P371 WeakPolarHBondContact O-CD 3.43Å
370	T	54.8	Low	63.6	Low	47 Å²	47	91.6 Å²	91.6	29%	0.288	50%	0.496	S	S	.	.			trans	-110.7	102.1	-179.1	59.7	0	0	0	0	111.4	V372 L387	T370-V372 PolarHBondContact O-N 3.31Å; T370-L387 HydrophobicContact CG2-CD1 3.66Å
371	P	51.1	Low	63.2	Low	129 Å²	129	89 Å²	89	84%	0.838	49%	0.488	S	S	*	.			trans	-80.5	-2.4	-165.6	27.8	-32.7	0	0	0	116.2	N369	N369-P371 WeakPolarHBondContact O-CD 3.43Å
372	V	57.3	Low	63	Low	88 Å²	88	84 Å²	84	53%	0.533	47%	0.465	S	S	.	.			trans	-141.6	90.6	179	-168.7	0	0	0	0	110.2	T370 F374	T370-V372 PolarHBondContact O-N 3.31Å; V372-F374 HydrophobicContact CG1-CD2 4.29Å; V372-F374 HydrophobicContact CG1-CE1 3.96Å; V372-F374 HydrophobicContact CG1-CE2 3.68Å; V372-F374 HydrophobicContact CG1-CZ 3.49Å; V372-F374 VanDerWaalsContact CG1-CZ 3.49Å
373	S	59.6	Low	62.9	Low	56 Å²	56	83.4 Å²	83.4	39%	0.392	46%	0.464	S	S	.	.			trans	-98.3	115.6	167.2	69.7	0	0	0	0	109.3
374	F	64.8	Low	63	Low	95 Å²	95	82.4 Å²	82.4	42%	0.417	46%	0.459	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-76.7	149.1	175.5	-61	-83.5	0	0	0	110.4	V372 W382 V386 L387 V388 R389	V372-F374 HydrophobicContact CG1-CD2 4.29Å; V372-F374 HydrophobicContact CG1-CE1 3.96Å; V372-F374 HydrophobicContact CG1-CE2 3.68Å; V372-F374 HydrophobicContact CG1-CZ 3.49Å; V372-F374 VanDerWaalsContact CG1-CZ 3.49Å; F374-W382 HydrophobicContact CB-CH2 3.46Å; F374-W382 VanDerWaalsContact CB-CH2 3.46Å; F374-W382 HydrophobicContact CB-CZ3 3.53Å; F374-W382 HydrophobicContact CD2-CZ3 4.1Å; F374-W382 HydrophobicContact CG-CH2 4.24Å; F374-W382 AromaticContact CG-CZ3 3.93Å; F374-W382 HydrophobicContact CG-CZ3 3.93Å; F374-V386 HydrophobicContact CD2-CG1 3.84Å; F374-V386 HydrophobicContact CE2-CG1 4.3Å; F374-L387 PolarHBondContact N-O 3.49Å; F374-V388 CarbonylContact O-C 3.6Å; F374-V388 WeakPolarHBondContact O-CA 3.46Å; F374-R389 PolarHBondContact O-N 3.42Å
375	R	64.9	Low	63.6	Low	223 Å²	223	77.8 Å²	77.8	84%	0.842	45%	0.447	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-73.7	134	170.4	178.9	179.2	-82.7	177.9	-4.6	108.1
376	W	75.6	Confident	64.4	Low	40 Å²	40	75.9 Å²	75.9	15%	0.152	42%	0.422	C	S	.	.	P	Polyproline II helix	trans	-62.7	136.8	176.9	-174.1	78.5	0	0	0	110.8	E378 W382 V388 R389 H390 L405 P406	W376-E378 HydrophobicContact CH2-CB 3.72Å; W376-E378 HydrophobicContact CH2-CG 3.92Å; W376-E378 HydrophobicContact CZ2-CB 4.39Å; W376-E378 HydrophobicContact CZ3-CB 4.03Å; W376-W382 AromaticContact CD1-NE1 3.9Å; W376-V388 HydrophobicContact CB-CG1 3.34Å; W376-V388 HydrophobicContact CG-CG1 4.03Å; W376-V388 VanDerWaalsContact N-CG1 3.34Å; W376-R389 PolarHBondContact N-O 2.92Å; W376-H390 HydrophobicContact CB-CB 4.08Å; W376-H390 AromaticContact CD2-CD2 3.85Å; W376-H390 AromaticContact CE3-CD2 3.63Å; W376-H390 AromaticContact CE3-NE2 3.91Å; W376-H390 AromaticContact CG-CD2 3.99Å; W376-L405 HydrophobicContact CH2-CD2 3.61Å; W376-L405 HydrophobicContact CH2-CG 4.37Å; W376-L405 HydrophobicContact CZ2-CD2 3.92Å; W376-L405 HydrophobicContact CZ2-CG 4.25Å; W376-L405 HydrophobicContact CZ3-CD2 4.5Å; W376-P406 HydrophobicContact CD2-CG 4.29Å; W376-P406 HydrophobicContact CG-CG 4.05Å
377	S	70.6	Confident	65.4	Low	37 Å²	37	74.3 Å²	74.3	26%	0.259	41%	0.407	S	S	.	.			trans	-130.6	139.1	173.8	43.3	0	0	0	0	109.3	S379 T380	S377-S379 VanDerWaalsContact C-N 3.33Å; S377-T380 WeakPolarHBondContact OG-CB 3.38Å; S377-T380 PolarHBondContact OG-OG1 3.3Å
378	E	67.5	Low	66.3	Low	97 Å²	97	71.3 Å²	71.3	45%	0.453	40%	0.396	S	S	.	.	T	Hydrogen-bonded Turn	trans	-72	-28.8	-175.6	-169.7	165.1	-169.5	0	0	112.7	P270 R274 W376	P270-E378 WeakPolarHBondContact CG-O 3.49Å; R274-E378 VanDerWaalsContact CZ-O 3.3Å; R274-E378 PolarHBondContact NH1-O 2.99Å; R274-E378 IonicContact NH1-OE1 3.92Å; R274-E378 PolarHBondContact NH2-O 3.01Å; W376-E378 HydrophobicContact CH2-CB 3.72Å; W376-E378 HydrophobicContact CH2-CG 3.92Å; W376-E378 HydrophobicContact CZ2-CB 4.39Å; W376-E378 HydrophobicContact CZ3-CB 4.03Å
379	S	64.9	Low	67.2	Low	86 Å²	86	72.3 Å²	72.3	60%	0.601	38%	0.384	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.6	1.8	-178.1	57.7	0	0	0	0	114.5	S377	S377-S379 VanDerWaalsContact C-N 3.33Å
380	T	70.2	Confident	68.1	Low	33 Å²	33	67.5 Å²	67.5	20%	0.202	36%	0.357	C	S	.	.			trans	-112.9	132.7	-174.1	-46.1	0	0	0	0	111.7	S377 W382	S377-T380 WeakPolarHBondContact OG-CB 3.38Å; S377-T380 PolarHBondContact OG-OG1 3.3Å; T380-W382 VanDerWaalsContact O-CD1 3.25Å; T380-W382 PolarHBondContact O-NE1 3.23Å
381	V	71.1	Confident	68.6	Low	48 Å²	48	68.7 Å²	68.7	29%	0.291	37%	0.367	S	S	.	.	P	Polyproline II helix	trans	-84.9	127	171.5	-178.5	0	0	0	0	108.7	P56 Y401 V403	P56-V381 HydrophobicContact CG-CG1 4.14Å; V381-Y401 HydrophobicContact CG1-CD1 3.79Å; V381-V403 HydrophobicContact CG1-CG2 4.14Å; V381-V403 HydrophobicContact CG2-CG2 4.11Å
382	W	75.7	Confident	69.3	Low	13 Å²	13	73 Å²	73	5%	0.049	37%	0.367	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.7	125.1	-176.9	-62	89.6	0	0	0	111.1	W359 F374 W376 T380 V386 V388 N402	W359-W382 HydrophobicContact CH2-CB 3.76Å; W359-W382 AromaticContact CH2-CD1 3.84Å; W359-W382 HydrophobicContact CH2-CD2 4.16Å; W359-W382 AromaticContact CH2-CG 3.6Å; W359-W382 HydrophobicContact CH2-CG 3.6Å; W359-W382 HydrophobicContact CZ2-CB 4.14Å; W359-W382 AromaticContact CZ2-CD1 3.66Å; W359-W382 AromaticContact CZ2-CG 3.89Å; W359-W382 HydrophobicContact CZ2-CG 3.89Å; F374-W382 HydrophobicContact CB-CH2 3.46Å; F374-W382 VanDerWaalsContact CB-CH2 3.46Å; F374-W382 HydrophobicContact CB-CZ3 3.53Å; F374-W382 HydrophobicContact CD2-CZ3 4.1Å; F374-W382 HydrophobicContact CG-CH2 4.24Å; F374-W382 AromaticContact CG-CZ3 3.93Å; F374-W382 HydrophobicContact CG-CZ3 3.93Å; W376-W382 AromaticContact CD1-NE1 3.9Å; T380-W382 VanDerWaalsContact O-CD1 3.25Å; T380-W382 PolarHBondContact O-NE1 3.23Å; W382-V386 HydrophobicContact CE3-CB 4.36Å; W382-V386 HydrophobicContact CE3-CG1 3.63Å; W382-V386 HydrophobicContact CZ3-CG1 3.92Å; W382-V388 HydrophobicContact CD2-CG2 3.56Å; W382-V388 HydrophobicContact CE3-CG2 3.42Å; W382-V388 VanDerWaalsContact CE3-CG2 3.42Å; W382-V388 HydrophobicContact CG-CG2 4.27Å; W382-V388 HydrophobicContact CH2-CG2 3.9Å; W382-V388 HydrophobicContact CZ2-CG1 4.32Å; W382-V388 HydrophobicContact CZ2-CG2 4.03Å; W382-V388 HydrophobicContact CZ3-CG2 3.6Å; W382-N402 HydrophobicContact CB-CB 4.23Å; W382-N402 PolarHBondContact N-O 3.28Å; W382-N402 VanDerWaalsContact N-O 3.08Å; W382-N402 WeakPolarHBondContact O-CB 3.3Å; W382-N402 PolarHBondContact O-N 3.22Å
383	P	72.2	Confident	70	Confident	23 Å²	23	69.6 Å²	69.6	15%	0.149	35%	0.347	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-75.8	165	177.1	28.5	-30.6	0	0	0	111.9	I54 G385 V386 A397	I54-P383 HydrophobicContact CG2-CB 4.29Å; I54-P383 HydrophobicContact CG2-CG 4.21Å; P383-G385 PolarHBondContact O-N 3.33Å; P383-V386 HydrophobicContact CG-CG2 3.69Å; P383-V386 WeakPolarHBondContact O-CG2 3.38Å; P383-V386 PolarHBondContact O-N 3.28Å; P383-A397 WeakPolarHBondContact O-CB 3.4Å
384	Q	74.3	Confident	70.6	Confident	137 Å²	137	67.1 Å²	67.1	64%	0.64	33%	0.329	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.2	135.3	-176.5	-167.4	175.8	29.9	0	0	112.7	V386 V398 G399	Q384-V386 VanDerWaalsContact C-N 3.32Å; Q384-V386 PolarHBondContact O-N 2.87Å; Q384-V398 PolarHBondContact NE2-O 2.8Å; Q384-G399 VanDerWaalsContact CA-O 3.28Å; Q384-G399 WeakPolarHBondContact CA-O 3.39Å; Q384-G399 VanDerWaalsContact CB-O 3.31Å; Q384-G399 WeakPolarHBondContact CB-O 3.37Å
385	G	69.5	Low	71.2	Confident	35 Å²	35	63.4 Å²	63.4	36%	0.361	31%	0.312	S	S	.	.	T	Hydrogen-bonded Turn	trans	85.8	-7.7	173.8	0	0	0	0	0	115.4	P383 A397	P383-G385 PolarHBondContact O-N 3.33Å; G385-A397 WeakPolarHBondContact CA-O 3.28Å; G385-A397 PolarHBondContact N-O 2.99Å
386	V	75.9	Confident	71.8	Confident	31 Å²	31	57 Å²	57	19%	0.188	29%	0.291	C	S	.	.			trans	-67.9	139.8	178.7	-179.5	0	0	0	0	111.5	F374 W382 P383 Q384 V388 A397	F374-V386 HydrophobicContact CD2-CG1 3.84Å; F374-V386 HydrophobicContact CE2-CG1 4.3Å; W382-V386 HydrophobicContact CE3-CB 4.36Å; W382-V386 HydrophobicContact CE3-CG1 3.63Å; W382-V386 HydrophobicContact CZ3-CG1 3.92Å; P383-V386 HydrophobicContact CG-CG2 3.69Å; P383-V386 WeakPolarHBondContact O-CG2 3.38Å; P383-V386 PolarHBondContact O-N 3.28Å; Q384-V386 VanDerWaalsContact C-N 3.32Å; Q384-V386 PolarHBondContact O-N 2.87Å; V386-V388 HydrophobicContact CG1-CG2 4.12Å; V386-A397 PolarHBondContact O-N 3.37Å
387	L	74.7	Confident	71.9	Confident	33 Å²	33	55.1 Å²	55.1	17%	0.173	28%	0.284	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.3	121.7	177.7	-65.3	168.5	0	0	0	109.9	L362 T370 F374 L394 Y395 K396	L362-L387 HydrophobicContact CD2-CD2 4.47Å; T370-L387 HydrophobicContact CG2-CD1 3.66Å; F374-L387 PolarHBondContact N-O 3.49Å; L387-L394 HydrophobicContact CB-CD1 4.43Å; L387-L394 HydrophobicContact CB-CD2 4.28Å; L387-L394 HydrophobicContact CB-CG 4.36Å; L387-L394 HydrophobicContact CD1-CD2 4.24Å; L387-L394 HydrophobicContact CD2-CD2 3.9Å; L387-L394 HydrophobicContact CD2-CG 4.34Å; L387-L394 HydrophobicContact CG-CD2 4.37Å; L387-Y395 WeakPolarHBondContact CA-O 3.28Å; L387-K396 HydrophobicContact CD2-CB 3.82Å; L387-K396 HydrophobicContact CD2-CG 4.11Å
388	V	73.1	Confident	72.1	Confident	0 Å²	0	55.8 Å²	55.8	0%	0	29%	0.286	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.8	136.3	-178.6	-179.4	0	0	0	0	110.2	W359 F374 W376 W382 V386 Y395	W359-V388 HydrophobicContact CH2-CB 3.78Å; W359-V388 HydrophobicContact CH2-CG1 4.46Å; W359-V388 HydrophobicContact CH2-CG2 3.43Å; W359-V388 VanDerWaalsContact CH2-CG2 3.43Å; W359-V388 HydrophobicContact CZ3-CB 3.73Å; W359-V388 HydrophobicContact CZ3-CG2 3.67Å; F374-V388 CarbonylContact O-C 3.6Å; F374-V388 WeakPolarHBondContact O-CA 3.46Å; W376-V388 HydrophobicContact CB-CG1 3.34Å; W376-V388 HydrophobicContact CG-CG1 4.03Å; W376-V388 VanDerWaalsContact N-CG1 3.34Å; W382-V388 HydrophobicContact CD2-CG2 3.56Å; W382-V388 HydrophobicContact CE3-CG2 3.42Å; W382-V388 VanDerWaalsContact CE3-CG2 3.42Å; W382-V388 HydrophobicContact CG-CG2 4.27Å; W382-V388 HydrophobicContact CH2-CG2 3.9Å; W382-V388 HydrophobicContact CZ2-CG1 4.32Å; W382-V388 HydrophobicContact CZ2-CG2 4.03Å; W382-V388 HydrophobicContact CZ3-CG2 3.6Å; V386-V388 HydrophobicContact CG1-CG2 4.12Å; V388-Y395 PolarHBondContact N-O 3.48Å; V388-Y395 PolarHBondContact O-N 2.92Å
389	R	71.3	Confident	72.1	Confident	123 Å²	123	51.3 Å²	51.3	46%	0.464	27%	0.265	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-94	120.8	174.8	-170.1	178.1	177.1	86.4	-0.6	109.8	F374 W376 L394	F374-R389 PolarHBondContact O-N 3.42Å; W376-R389 PolarHBondContact N-O 2.92Å; R389-L394 HydrophobicContact CB-CD1 4.41Å
390	H	71.4	Confident	72.2	Confident	43 Å²	43	49.9 Å²	49.9	20%	0.199	26%	0.256	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-139.5	138.7	174.9	-174.7	-95	0	0	0	109.3	W376 R392 C393 Y395 P406 S407	W376-H390 HydrophobicContact CB-CB 4.08Å; W376-H390 AromaticContact CD2-CD2 3.85Å; W376-H390 AromaticContact CE3-CD2 3.63Å; W376-H390 AromaticContact CE3-NE2 3.91Å; W376-H390 AromaticContact CG-CD2 3.99Å; H390-R392 VanDerWaalsContact C-N 3.31Å; H390-R392 PolarHBondContact O-N 3.33Å; H390-R392 VanDerWaalsContact O-N 3.12Å; H390-C393 PolarHBondContact N-O 3.44Å; H390-C393 VanDerWaalsContact N-O 3.09Å; H390-C393 PolarHBondContact O-N 2.9Å; H390-Y395 HydrophobicContact CB-CD2 4.02Å; H390-Y395 HydrophobicContact CB-CE2 3.97Å; H390-Y395 WeakPolarHBondContact O-CE2 3.17Å; H390-P406 HydrophobicContact CB-CB 4.26Å; H390-P406 HydrophobicContact CB-CG 3.63Å; H390-S407 PolarHBondContact CE1-OG 3.43Å
391	S	65	Low	72.1	Confident	73 Å²	73	50.2 Å²	50.2	51%	0.51	25%	0.253	S	S	.	.	T	Hydrogen-bonded Turn	trans	44.5	48.3	176.7	68.7	0	0	0	0	114.8	C393	S391-C393 PolarHBondContact O-N 3.47Å
392	R	66.9	Low	72.1	Confident	219 Å²	219	47.9 Å²	47.9	83%	0.826	24%	0.24	S	C	*	.	T	Hydrogen-bonded Turn	trans	63.4	-0.2	-177.4	-56.7	-177.3	-180	177.4	0.6	117	H390	H390-R392 VanDerWaalsContact C-N 3.31Å; H390-R392 PolarHBondContact O-N 3.33Å; H390-R392 VanDerWaalsContact O-N 3.12Å
393	C	71.1	Confident	72.1	Confident	16 Å²	16	47.3 Å²	47.3	11%	0.108	24%	0.238	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-105.7	155.3	176.4	-59.8	0	0	0	0	110.8	K361 H390 S391 Y395	K361-C393 WeakPolarHBondContact CE-SG 3.45Å; K361-C393 HydrophobicContact CG-CB 4.48Å; H390-C393 PolarHBondContact N-O 3.44Å; H390-C393 VanDerWaalsContact N-O 3.09Å; H390-C393 PolarHBondContact O-N 2.9Å; S391-C393 PolarHBondContact O-N 3.47Å; C393-Y395 HydrophobicContact CB-CD2 4.41Å; C393-Y395 HydrophobicContact CB-CE2 3.7Å
394	L	72.9	Confident	72.3	Confident	4 Å²	4	46.3 Å²	46.3	2%	0.021	23%	0.231	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-97.4	134.6	170.9	-158	77.5	0	0	0	109.2	L362 Y367 L387 R389	L362-L394 HydrophobicContact CB-CB 4.22Å; L362-L394 HydrophobicContact CB-CD2 4.5Å; L362-L394 HydrophobicContact CD2-CD2 3.91Å; L362-L394 PolarHBondContact N-O 2.83Å; Y367-L394 HydrophobicContact CD1-CB 3.88Å; Y367-L394 HydrophobicContact CD1-CD2 4.17Å; Y367-L394 HydrophobicContact CE1-CB 3.38Å; Y367-L394 HydrophobicContact CE1-CD2 4.44Å; L387-L394 HydrophobicContact CB-CD1 4.43Å; L387-L394 HydrophobicContact CB-CD2 4.28Å; L387-L394 HydrophobicContact CB-CG 4.36Å; L387-L394 HydrophobicContact CD1-CD2 4.24Å; L387-L394 HydrophobicContact CD2-CD2 3.9Å; L387-L394 HydrophobicContact CD2-CG 4.34Å; L387-L394 HydrophobicContact CG-CD2 4.37Å; R389-L394 HydrophobicContact CB-CD1 4.41Å
395	Y	76.3	Confident	72.4	Confident	18 Å²	18	42.3 Å²	42.3	7%	0.071	21%	0.214	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-121.9	138	177.7	-64.5	-88.1	0	0	0	109.8	W359 Q360 K361 L387 V388 H390 C393 P406	W359-Y395 HydrophobicContact CB-CD1 3.99Å; W359-Y395 HydrophobicContact CB-CG 4.37Å; Q360-Y395 CarbonylContact O-C 3.55Å; Q360-Y395 WeakPolarHBondContact O-CA 3.44Å; K361-Y395 HydrophobicContact CB-CD1 3.99Å; K361-Y395 HydrophobicContact CB-CE1 3.77Å; K361-Y395 HydrophobicContact CD-CE1 4.37Å; K361-Y395 HydrophobicContact CG-CD1 4.41Å; K361-Y395 HydrophobicContact CG-CE1 3.95Å; L387-Y395 WeakPolarHBondContact CA-O 3.28Å; V388-Y395 PolarHBondContact N-O 3.48Å; V388-Y395 PolarHBondContact O-N 2.92Å; H390-Y395 HydrophobicContact CB-CD2 4.02Å; H390-Y395 HydrophobicContact CB-CE2 3.97Å; H390-Y395 WeakPolarHBondContact O-CE2 3.17Å; C393-Y395 HydrophobicContact CB-CD2 4.41Å; C393-Y395 HydrophobicContact CB-CE2 3.7Å; Y395-P406 HydrophobicContact CD1-CB 4.05Å; Y395-P406 HydrophobicContact CD2-CB 3.74Å; Y395-P406 HydrophobicContact CE1-CB 4.32Å; Y395-P406 WeakPolarHBondContact CE1-O 3.21Å; Y395-P406 HydrophobicContact CE2-CB 4.01Å; Y395-P406 HydrophobicContact CG-CB 3.75Å
396	K	78	Confident	72.2	Confident	88 Å²	88	41.1 Å²	41.1	38%	0.383	20%	0.2	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-102.3	131.2	174.1	-175.2	179.8	178.5	-179.4	0	110	Q360 L362 L387 V398	Q360-K396 PolarHBondContact N-O 3.42Å; Q360-K396 PolarHBondContact O-N 2.93Å; L362-K396 HydrophobicContact CD1-CB 4.34Å; L387-K396 HydrophobicContact CD2-CB 3.82Å; L387-K396 HydrophobicContact CD2-CG 4.11Å; K396-V398 PolarHBondContact O-N 2.89Å
397	A	77.4	Confident	71.8	Confident	1 Å²	1	43 Å²	43	1%	0.008	21%	0.214	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-71.4	124.1	172.4	0	0	0	0	0	110.7	W359 P383 G385 V386 N402	W359-A397 HydrophobicContact CE3-CB 4.38Å; W359-A397 HydrophobicContact CH2-CB 4.29Å; W359-A397 HydrophobicContact CZ3-CB 3.9Å; P383-A397 WeakPolarHBondContact O-CB 3.4Å; G385-A397 WeakPolarHBondContact CA-O 3.28Å; G385-A397 PolarHBondContact N-O 2.99Å; V386-A397 PolarHBondContact O-N 3.37Å; A397-N402 VanDerWaalsContact CA-ND2 3.35Å; A397-N402 WeakPolarHBondContact CA-ND2 3.32Å; A397-N402 HydrophobicContact CB-CB 4Å; A397-N402 VanDerWaalsContact CB-ND2 3.28Å; A397-N402 WeakPolarHBondContact CB-ND2 3.45Å
398	V	74.4	Confident	71.9	Confident	51 Å²	51	43.9 Å²	43.9	31%	0.309	22%	0.219	S	C	.	.			trans	-101.2	-32.8	-178.4	-178.2	0	0	0	0	112.3	R358 Q360 Q384 K396	R358-V398 PolarHBondContact O-N 3.48Å; Q360-V398 HydrophobicContact CB-CG2 3.7Å; Q384-V398 PolarHBondContact NE2-O 2.8Å; K396-V398 PolarHBondContact O-N 2.89Å
399	G	67.4	Low	72.1	Confident	2 Å²	2	48.9 Å²	48.9	2%	0.021	25%	0.249	C	C	.	.	S	Bend	trans	-79	160.9	179.1	0	0	0	0	0	113.1	Q384 Y401	Q384-G399 VanDerWaalsContact CA-O 3.28Å; Q384-G399 WeakPolarHBondContact CA-O 3.39Å; Q384-G399 VanDerWaalsContact CB-O 3.31Å; Q384-G399 WeakPolarHBondContact CB-O 3.37Å; G399-Y401 VanDerWaalsContact C-N 3.32Å
400	S	67.1	Low	72.2	Confident	57 Å²	57	44.4 Å²	44.4	40%	0.399	24%	0.237	S	C	.	.	S	Bend	trans	-63.3	-40.4	171.2	43.9	0	0	0	0	111.5
401	Y	68.7	Low	72.5	Confident	39 Å²	39	42.5 Å²	42.5	15%	0.153	23%	0.228	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-113	135.2	165.7	-70.1	-104.1	0	0	0	108.2	P56 E57 P58 V59 H355 G357 V381 G399	P56-Y401 HydrophobicContact CB-CD1 4.1Å; P56-Y401 HydrophobicContact CB-CD2 4.5Å; P56-Y401 HydrophobicContact CB-CE1 3.69Å; P56-Y401 HydrophobicContact CB-CE2 4.15Å; P56-Y401 HydrophobicContact CB-CG 4.47Å; P56-Y401 HydrophobicContact CG-CD1 3.85Å; P56-Y401 HydrophobicContact CG-CE1 3.33Å; P56-Y401 PolarHBondContact O-OH 3.19Å; E57-Y401 WeakPolarHBondContact O-CE2 3.41Å; E57-Y401 PolarHBondContact O-OH 2.85Å; P58-Y401 WeakPolarHBondContact CA-OH 2.79Å; V59-Y401 HydrophobicContact CB-CD2 4.48Å; V59-Y401 HydrophobicContact CB-CE2 4.25Å; V59-Y401 HydrophobicContact CG2-CD2 3.11Å; V59-Y401 HydrophobicContact CG2-CE2 3.22Å; V59-Y401 HydrophobicContact CG2-CG 4.04Å; H355-Y401 WeakPolarHBondContact O-CB 3.14Å; G357-Y401 WeakPolarHBondContact CA-O 3.46Å; G357-Y401 PolarHBondContact N-O 3.4Å; V381-Y401 HydrophobicContact CG1-CD1 3.79Å; G399-Y401 VanDerWaalsContact C-N 3.32Å
402	N	71.6	Confident	73.1	Confident	0 Å²	0	40.4 Å²	40.4	0%	0	22%	0.215	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-134.3	102.7	176.1	-164.9	22.1	0	0	0	110.2	L356 R358 W359 W382 A397	L356-N402 PolarHBondContact O-OD1 3Å; R358-N402 PolarHBondContact N-OD1 3.23Å; W359-N402 VanDerWaalsContact CE3-ND2 3.31Å; W359-N402 WeakPolarHBondContact CH2-ND2 3.32Å; W359-N402 WeakPolarHBondContact CZ2-ND2 3.18Å; W359-N402 WeakPolarHBondContact CZ3-ND2 3.42Å; W359-N402 PolarHBondContact NE1-ND2 3.49Å; W359-N402 PolarHBondContact NE1-OD1 2.77Å; W382-N402 HydrophobicContact CB-CB 4.23Å; W382-N402 PolarHBondContact N-O 3.28Å; W382-N402 VanDerWaalsContact N-O 3.08Å; W382-N402 WeakPolarHBondContact O-CB 3.3Å; W382-N402 PolarHBondContact O-N 3.22Å; A397-N402 VanDerWaalsContact CA-ND2 3.35Å; A397-N402 WeakPolarHBondContact CA-ND2 3.32Å; A397-N402 HydrophobicContact CB-CB 4Å; A397-N402 VanDerWaalsContact CB-ND2 3.28Å; A397-N402 WeakPolarHBondContact CB-ND2 3.45Å
403	V	74.3	Confident	73.7	Confident	1 Å²	1	39 Å²	39	1%	0.006	21%	0.209	C	C	.	.			trans	-113.1	-12.5	-179.3	-174.9	0	0	0	0	110.7	P270 I273 R274 L356 V381	P270-V403 HydrophobicContact CB-CG1 3.41Å; P270-V403 VanDerWaalsContact CB-CG1 3.41Å; P270-V403 VanDerWaalsContact O-CG1 3.25Å; P270-V403 WeakPolarHBondContact O-CG1 3.1Å; I273-V403 HydrophobicContact CB-CG1 4.48Å; I273-V403 HydrophobicContact CD1-CG2 4.4Å; R274-V403 HydrophobicContact CG-CG1 4.21Å; R274-V403 VanDerWaalsContact CZ-O 3.28Å; R274-V403 PolarHBondContact NE-O 3.16Å; R274-V403 PolarHBondContact NH2-O 3.13Å; L356-V403 PolarHBondContact O-N 2.78Å; V381-V403 HydrophobicContact CG1-CG2 4.14Å; V381-V403 HydrophobicContact CG2-CG2 4.11Å
404	A	75.9	Confident	74.3	Confident	2 Å²	2	38.7 Å²	38.7	2%	0.017	21%	0.206	C	C	.	.	S	Bend	trans	-53.9	154.3	-179.4	0	0	0	0	0	114	L356 W359 P406 H411	L356-A404 HydrophobicContact CD1-CB 4Å; L356-A404 HydrophobicContact CG-CB 4.04Å; L356-A404 PolarHBondContact O-N 3.5Å; W359-A404 PolarHBondContact NE1-O 2.8Å; A404-P406 WeakPolarHBondContact O-CD 3.07Å; A404-H411 HydrophobicContact CB-CB 4.22Å
405	L	77.4	Confident	74.6	Confident	53 Å²	53	39.4 Å²	39.4	28%	0.277	21%	0.209	S	C	.	.			trans	-76.7	121.3	167.6	-79.9	134.2	0	0	0	109.4	W376 S407 D408 H411	W376-L405 HydrophobicContact CH2-CD2 3.61Å; W376-L405 HydrophobicContact CH2-CG 4.37Å; W376-L405 HydrophobicContact CZ2-CD2 3.92Å; W376-L405 HydrophobicContact CZ2-CG 4.25Å; W376-L405 HydrophobicContact CZ3-CD2 4.5Å; L405-S407 PolarHBondContact O-N 2.95Å; L405-S407 VanDerWaalsContact O-N 3.13Å; L405-D408 HydrophobicContact CB-CB 4.1Å; L405-D408 PolarHBondContact O-N 3.45Å; L405-D408 VanDerWaalsContact O-N 3.16Å; L405-H411 PolarHBondContact N-ND1 3.22Å
406	P	65.3	Low	74.9	Confident	10 Å²	10	44.2 Å²	44.2	7%	0.065	23%	0.23	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.4	-20.1	-173.5	19.5	-30.2	0	0	0	115.1	W359 W376 H390 Y395 A404	W359-P406 HydrophobicContact CB-CB 4.13Å; W359-P406 HydrophobicContact CD2-CB 3.96Å; W359-P406 HydrophobicContact CG-CB 3.66Å; W376-P406 HydrophobicContact CD2-CG 4.29Å; W376-P406 HydrophobicContact CG-CG 4.05Å; H390-P406 HydrophobicContact CB-CB 4.26Å; H390-P406 HydrophobicContact CB-CG 3.63Å; Y395-P406 HydrophobicContact CD1-CB 4.05Å; Y395-P406 HydrophobicContact CD2-CB 3.74Å; Y395-P406 HydrophobicContact CE1-CB 4.32Å; Y395-P406 WeakPolarHBondContact CE1-O 3.21Å; Y395-P406 HydrophobicContact CE2-CB 4.01Å; Y395-P406 HydrophobicContact CG-CB 3.75Å; A404-P406 WeakPolarHBondContact O-CD 3.07Å
407	S	68.4	Low	74.9	Confident	69 Å²	69	43 Å²	43	48%	0.483	23%	0.228	S	C	.	.	T	Hydrogen-bonded Turn	trans	-97.9	-6.5	178.3	50.7	0	0	0	0	114.6	H390 L405	H390-S407 PolarHBondContact CE1-OG 3.43Å; L405-S407 PolarHBondContact O-N 2.95Å; L405-S407 VanDerWaalsContact O-N 3.13Å
408	D	75.7	Confident	75	Confident	53 Å²	53	43.2 Å²	43.2	28%	0.283	23%	0.229	S	C	.	.			trans	-89.2	119.1	-177.3	-172.3	14.9	0	0	0	112.4	L405 S410 H411 A412	L405-D408 HydrophobicContact CB-CB 4.1Å; L405-D408 PolarHBondContact O-N 3.45Å; L405-D408 VanDerWaalsContact O-N 3.16Å; D408-S410 VanDerWaalsContact C-N 3.26Å; D408-S410 PolarHBondContact O-N 2.87Å; D408-S410 WeakPolarHBondContact OD1-CB 3.46Å; D408-S410 PolarHBondContact OD1-N 3.26Å; D408-S410 PolarHBondContact OD1-OG 2.92Å; D408-S410 WeakPolarHBondContact OD2-CB 3.18Å; D408-S410 PolarHBondContact OD2-OG 3.47Å; D408-H411 HydrophobicContact CB-CB 4.49Å; D408-H411 IonicContact OD2-CD2 3.52Å; D408-H411 PolarHBondContact OD2-CD2 2.95Å; D408-H411 IonicContact OD2-CG 3.19Å; D408-H411 PolarHBondContact OD2-N 2.95Å; D408-H411 IonicContact OD2-NE2 2.77Å; D408-A412 PolarHBondContact O-N 3.35Å
409	V	76.7	Confident	75.2	Confident	104 Å²	104	44 Å²	44	63%	0.63	23%	0.229	S	C	*	.	H	α-helix	trans	-70	-27.3	175.9	-176.1	0	0	0	0	110.8	A412 R413	V409-A412 PolarHBondContact O-N 3.32Å; V409-R413 HydrophobicContact CG1-CG 4.35Å; V409-R413 WeakPolarHBondContact O-CG 3.49Å; V409-R413 PolarHBondContact O-N 3.23Å
410	S	74.9	Confident	75.7	Confident	29 Å²	29	49.8 Å²	49.8	20%	0.203	25%	0.254	C	S	.	.	H	α-helix	trans	-68	-44.7	-177.6	98.2	0	0	0	0	111.4	K281 D408 A412 R413 F414	K281-S410 PolarHBondContact NZ-OG 2.92Å; D408-S410 VanDerWaalsContact C-N 3.26Å; D408-S410 PolarHBondContact O-N 2.87Å; D408-S410 WeakPolarHBondContact OD1-CB 3.46Å; D408-S410 PolarHBondContact OD1-N 3.26Å; D408-S410 PolarHBondContact OD1-OG 2.92Å; D408-S410 WeakPolarHBondContact OD2-CB 3.18Å; D408-S410 PolarHBondContact OD2-OG 3.47Å; S410-A412 VanDerWaalsContact C-N 3.34Å; S410-A412 PolarHBondContact O-N 3.24Å; S410-R413 PolarHBondContact O-N 3.29Å; S410-F414 WeakPolarHBondContact O-CB 3.5Å; S410-F414 PolarHBondContact O-N 3.22Å
411	H	78	Confident	75.9	Confident	4 Å²	4	48 Å²	48	2%	0.019	24%	0.24	C	C	.	.	H	α-helix	trans	-62	-39.2	172.5	-71.9	-156.7	0	0	0	112.3	E278 L356 A404 L405 D408 F414 Y415	E278-H411 IonicContact OE1-CD2 3.33Å; E278-H411 IonicContact OE1-NE2 3.46Å; E278-H411 PolarHBondContact OE1-NE2 3.32Å; L356-H411 HydrophobicContact CD2-CB 4.15Å; A404-H411 HydrophobicContact CB-CB 4.22Å; L405-H411 PolarHBondContact N-ND1 3.22Å; D408-H411 HydrophobicContact CB-CB 4.49Å; D408-H411 IonicContact OD2-CD2 3.52Å; D408-H411 PolarHBondContact OD2-CD2 2.95Å; D408-H411 IonicContact OD2-CG 3.19Å; D408-H411 PolarHBondContact OD2-N 2.95Å; D408-H411 IonicContact OD2-NE2 2.77Å; H411-F414 PolarHBondContact O-N 3.14Å; H411-Y415 WeakPolarHBondContact O-CB 3.26Å; H411-Y415 PolarHBondContact O-N 3.44Å
412	A	76.6	Confident	76.4	Confident	28 Å²	28	48.2 Å²	48.2	23%	0.231	24%	0.244	C	C	.	.	H	α-helix	trans	-66.1	-38.6	177.3	0	0	0	0	0	112.5	D408 V409 S410 F416	D408-A412 PolarHBondContact O-N 3.35Å; V409-A412 PolarHBondContact O-N 3.32Å; S410-A412 VanDerWaalsContact C-N 3.34Å; S410-A412 PolarHBondContact O-N 3.24Å; A412-F416 WeakPolarHBondContact O-CB 3.28Å; A412-F416 PolarHBondContact O-N 3.49Å
413	R	80.4	Confident	77	Confident	189 Å²	189	51.8 Å²	51.8	71%	0.713	26%	0.257	S	S	*	.	H	α-helix	trans	-68	-42.7	174.7	-73.4	175.9	68.8	-179	1.2	111.5	V409 S410 F416 L417	V409-R413 HydrophobicContact CG1-CG 4.35Å; V409-R413 WeakPolarHBondContact O-CG 3.49Å; V409-R413 PolarHBondContact O-N 3.23Å; S410-R413 PolarHBondContact O-N 3.29Å; R413-F416 PolarHBondContact O-N 3.34Å; R413-L417 WeakPolarHBondContact O-CB 3.5Å; R413-L417 PolarHBondContact O-N 3.07Å
414	F	82.3	Confident	77.5	Confident	10 Å²	10	53 Å²	53	4%	0.044	26%	0.263	C	S	.	.	H	α-helix	trans	-58.8	-51.8	176.3	-172.9	-92.7	0	0	0	110.9	V277 L280 K281 L349 A353 L356 S410 H411 F416 L417 F418	V277-F414 HydrophobicContact CG1-CD1 4Å; V277-F414 HydrophobicContact CG1-CE1 4.09Å; V277-F414 HydrophobicContact CG1-CG 4.27Å; V277-F414 HydrophobicContact CG1-CZ 4.44Å; V277-F414 HydrophobicContact CG2-CE1 4.24Å; L280-F414 HydrophobicContact CB-CZ 4.49Å; K281-F414 HydrophobicContact CB-CD2 4.46Å; L349-F414 HydrophobicContact CD2-CE2 3.89Å; L349-F414 HydrophobicContact CD2-CZ 3.81Å; A353-F414 HydrophobicContact CB-CD1 4.11Å; A353-F414 HydrophobicContact CB-CE1 3.82Å; L356-F414 HydrophobicContact CD2-CD1 3.91Å; S410-F414 WeakPolarHBondContact O-CB 3.5Å; S410-F414 PolarHBondContact O-N 3.22Å; H411-F414 PolarHBondContact O-N 3.14Å; F414-F416 VanDerWaalsContact C-N 3.33Å; F414-F416 PolarHBondContact O-N 3.3Å; F414-L417 PolarHBondContact O-N 3.5Å; F414-L417 VanDerWaalsContact O-N 3.16Å; F414-F418 HydrophobicContact CD1-CD2 4.05Å; F414-F418 AromaticContact CD2-CD2 3.48Å; F414-F418 HydrophobicContact CD2-CD2 3.48Å; F414-F418 VanDerWaalsContact CD2-CD2 3.48Å; F414-F418 AromaticContact CD2-CE2 3.36Å; F414-F418 HydrophobicContact CD2-CE2 3.36Å; F414-F418 HydrophobicContact CE1-CD2 4.05Å; F414-F418 AromaticContact CE2-CD2 3.47Å; F414-F418 HydrophobicContact CE2-CD2 3.47Å; F414-F418 VanDerWaalsContact CE2-CD2 3.47Å; F414-F418 AromaticContact CE2-CE2 3.39Å; F414-F418 HydrophobicContact CE2-CE2 3.39Å; F414-F418 HydrophobicContact CE2-CZ 4.41Å; F414-F418 AromaticContact CG-CD2 3.76Å; F414-F418 HydrophobicContact CG-CD2 3.76Å; F414-F418 HydrophobicContact CG-CE2 4.08Å; F414-F418 AromaticContact CZ-CD2 3.77Å; F414-F418 HydrophobicContact CZ-CD2 3.77Å; F414-F418 HydrophobicContact CZ-CE2 4.13Å; F414-F418 WeakPolarHBondContact O-CD2 3.49Å; F414-F418 PolarHBondContact O-N 3.24Å
415	Y	79.9	Confident	77.9	Confident	19 Å²	19	54.2 Å²	54.2	8%	0.075	27%	0.27	C	S	.	.	H	α-helix	trans	-58.8	-43.4	175.4	-173.7	-91.2	0	0	0	112.1	A353 G357 R358 H411 L417 H419	A353-Y415 WeakPolarHBondContact O-CD2 3.47Å; A353-Y415 WeakPolarHBondContact O-CE2 3.2Å; G357-Y415 VanDerWaalsContact C-CE2 3.46Å; G357-Y415 VanDerWaalsContact CA-CE2 3.41Å; G357-Y415 WeakPolarHBondContact O-CD2 3.38Å; R358-Y415 HydrophobicContact CB-CD1 3.42Å; R358-Y415 VanDerWaalsContact CB-CD1 3.42Å; R358-Y415 HydrophobicContact CB-CD2 4.15Å; R358-Y415 HydrophobicContact CB-CE1 3.7Å; R358-Y415 HydrophobicContact CB-CE2 4.39Å; R358-Y415 HydrophobicContact CB-CG 3.64Å; R358-Y415 HydrophobicContact CG-CD1 4.25Å; H411-Y415 WeakPolarHBondContact O-CB 3.26Å; H411-Y415 PolarHBondContact O-N 3.44Å; Y415-L417 VanDerWaalsContact C-N 3.34Å; Y415-L417 PolarHBondContact O-N 3.46Å; Y415-H419 HydrophobicContact CD1-CB 4.15Å; Y415-H419 HydrophobicContact CE1-CB 4.06Å; Y415-H419 AromaticContact CE1-CD2 3.59Å; Y415-H419 AromaticContact CE1-CG 3.92Å; Y415-H419 HydrophobicContact CE2-CB 4.47Å; Y415-H419 AromaticContact CE2-CD2 3.61Å; Y415-H419 HydrophobicContact CG-CB 4.44Å; Y415-H419 AromaticContact CZ-CD2 3.12Å; Y415-H419 AromaticContact CZ-CG 3.9Å; Y415-H419 AromaticContact CZ-NE2 3.86Å; Y415-H419 WeakPolarHBondContact O-CB 3.44Å; Y415-H419 PolarHBondContact O-N 3.3Å; Y415-H419 PolarHBondContact OH-CD2 3.05Å; Y415-H419 PolarHBondContact OH-NE2 3.48Å
416	F	82.3	Confident	78.4	Confident	119 Å²	119	55.1 Å²	55.1	52%	0.522	28%	0.275	S	S	.	.	H	α-helix	trans	-62.3	-41.3	177.4	179.2	-94.4	0	0	0	112.3	A412 R413 F414 R423	A412-F416 WeakPolarHBondContact O-CB 3.28Å; A412-F416 PolarHBondContact O-N 3.49Å; R413-F416 PolarHBondContact O-N 3.34Å; F414-F416 VanDerWaalsContact C-N 3.33Å; F414-F416 PolarHBondContact O-N 3.3Å; F416-R423 VanDerWaalsContact CD2-NH1 3.26Å; F416-R423 WeakPolarHBondContact O-CD 3.49Å; F416-R423 PolarHBondContact O-NH1 3.44Å
417	L	78.6	Confident	79.6	Confident	62 Å²	62	60 Å²	60	33%	0.325	30%	0.3	S	S	.	.	H	α-helix	trans	-71.7	-41.6	-176.6	-168.2	64	0	0	0	111.8	F284 R413 F414 Y415 I424	F284-L417 HydrophobicContact CE1-CD2 3.84Å; F284-L417 HydrophobicContact CZ-CD2 3.77Å; R413-L417 WeakPolarHBondContact O-CB 3.5Å; R413-L417 PolarHBondContact O-N 3.07Å; F414-L417 PolarHBondContact O-N 3.5Å; F414-L417 VanDerWaalsContact O-N 3.16Å; Y415-L417 VanDerWaalsContact C-N 3.34Å; Y415-L417 PolarHBondContact O-N 3.46Å; L417-I424 HydrophobicContact CD1-CD1 4.46Å; L417-I424 HydrophobicContact CD1-CG1 4.14Å; L417-I424 HydrophobicContact CD2-CD1 4.39Å; L417-I424 HydrophobicContact CG-CD1 4.08Å; L417-I424 HydrophobicContact CG-CG1 4.26Å
418	F	80	Confident	80.6	Confident	7 Å²	7	57.3 Å²	57.3	3%	0.031	28%	0.28	C	S	.	.	H	α-helix	trans	-107.1	-11	-168.2	-57.1	-65.5	0	0	0	115.6	F284 L349 H350 A353 F414 K420 I424	F284-F418 HydrophobicContact CD1-CZ 4.08Å; F284-F418 HydrophobicContact CD2-CE1 4.26Å; F284-F418 AromaticContact CD2-CZ 3.79Å; F284-F418 HydrophobicContact CD2-CZ 3.79Å; F284-F418 AromaticContact CE1-CZ 3.92Å; F284-F418 HydrophobicContact CE1-CZ 3.92Å; F284-F418 AromaticContact CE2-CE1 3.87Å; F284-F418 HydrophobicContact CE2-CE1 3.87Å; F284-F418 AromaticContact CE2-CZ 3.62Å; F284-F418 HydrophobicContact CE2-CZ 3.62Å; F284-F418 HydrophobicContact CG-CZ 4Å; F284-F418 HydrophobicContact CZ-CE1 4.16Å; F284-F418 AromaticContact CZ-CZ 3.68Å; F284-F418 HydrophobicContact CZ-CZ 3.68Å; L349-F418 HydrophobicContact CB-CB 4.31Å; L349-F418 HydrophobicContact CB-CD1 3.68Å; L349-F418 HydrophobicContact CB-CD2 4.5Å; L349-F418 HydrophobicContact CB-CE1 4.08Å; L349-F418 HydrophobicContact CB-CG 3.92Å; L349-F418 HydrophobicContact CD1-CD1 3.94Å; L349-F418 HydrophobicContact CD1-CE1 3.45Å; L349-F418 VanDerWaalsContact CD1-CE1 3.45Å; L349-F418 HydrophobicContact CD1-CZ 3.86Å; L349-F418 HydrophobicContact CD2-CZ 4.47Å; L349-F418 HydrophobicContact CG-CD1 4.37Å; L349-F418 HydrophobicContact CG-CE1 4.27Å; H350-F418 PolarHBondContact ND1-O 3.21Å; A353-F418 HydrophobicContact CB-CB 3.76Å; F414-F418 HydrophobicContact CD1-CD2 4.05Å; F414-F418 AromaticContact CD2-CD2 3.48Å; F414-F418 HydrophobicContact CD2-CD2 3.48Å; F414-F418 VanDerWaalsContact CD2-CD2 3.48Å; F414-F418 AromaticContact CD2-CE2 3.36Å; F414-F418 HydrophobicContact CD2-CE2 3.36Å; F414-F418 HydrophobicContact CE1-CD2 4.05Å; F414-F418 AromaticContact CE2-CD2 3.47Å; F414-F418 HydrophobicContact CE2-CD2 3.47Å; F414-F418 VanDerWaalsContact CE2-CD2 3.47Å; F414-F418 AromaticContact CE2-CE2 3.39Å; F414-F418 HydrophobicContact CE2-CE2 3.39Å; F414-F418 HydrophobicContact CE2-CZ 4.41Å; F414-F418 AromaticContact CG-CD2 3.76Å; F414-F418 HydrophobicContact CG-CD2 3.76Å; F414-F418 HydrophobicContact CG-CE2 4.08Å; F414-F418 AromaticContact CZ-CD2 3.77Å; F414-F418 HydrophobicContact CZ-CD2 3.77Å; F414-F418 HydrophobicContact CZ-CE2 4.13Å; F414-F418 WeakPolarHBondContact O-CD2 3.49Å; F414-F418 PolarHBondContact O-N 3.24Å; F418-K420 PolarHBondContact O-N 3.46Å; F418-K420 VanDerWaalsContact O-N 3.13Å; F418-I424 HydrophobicContact CD1-CD1 3.8Å; F418-I424 HydrophobicContact CE1-CD1 3.33Å; F418-I424 HydrophobicContact CZ-CD1 4.3Å
419	H	77.5	Confident	81.4	Confident	67 Å²	67	56 Å²	56	31%	0.31	27%	0.273	S	S	.	.	S	Bend	trans	-60.4	-26.7	177.2	175.7	-77.6	0	0	0	113.3	H350 Y415	H350-H419 PolarHBondContact CE1-O 3.22Å; H350-H419 PolarHBondContact ND1-O 3.39Å; Y415-H419 HydrophobicContact CD1-CB 4.15Å; Y415-H419 HydrophobicContact CE1-CB 4.06Å; Y415-H419 AromaticContact CE1-CD2 3.59Å; Y415-H419 AromaticContact CE1-CG 3.92Å; Y415-H419 HydrophobicContact CE2-CB 4.47Å; Y415-H419 AromaticContact CE2-CD2 3.61Å; Y415-H419 HydrophobicContact CG-CB 4.44Å; Y415-H419 AromaticContact CZ-CD2 3.12Å; Y415-H419 AromaticContact CZ-CG 3.9Å; Y415-H419 AromaticContact CZ-NE2 3.86Å; Y415-H419 WeakPolarHBondContact O-CB 3.44Å; Y415-H419 PolarHBondContact O-N 3.3Å; Y415-H419 PolarHBondContact OH-CD2 3.05Å; Y415-H419 PolarHBondContact OH-NE2 3.48Å
420	K	78.2	Confident	82.1	Confident	124 Å²	124	52.6 Å²	52.6	54%	0.539	26%	0.259	S	S	.	.	S	Bend	trans	-116.6	110.5	167.7	-63.6	-176.1	177.1	-176.9	0	107.9	F418 L422 R423	F418-K420 PolarHBondContact O-N 3.46Å; F418-K420 VanDerWaalsContact O-N 3.13Å; K420-L422 PolarHBondContact O-N 3.05Å; K420-L422 VanDerWaalsContact O-N 3.11Å; K420-R423 HydrophobicContact CB-CG 3.92Å; K420-R423 WeakPolarHBondContact O-CB 3.3Å; K420-R423 PolarHBondContact O-N 3.03Å
421	P	71.3	Confident	83	Confident	18 Å²	18	53.8 Å²	53.8	12%	0.117	26%	0.262	C	S	.	.	T	Hydrogen-bonded Turn	trans	-61.6	-26.9	-173.8	22	-30.1	0	0	0	112.1	H350 R423 Y480	H350-P421 HydrophobicContact CB-CB 4.09Å; P421-R423 VanDerWaalsContact C-N 3.3Å; P421-R423 PolarHBondContact O-N 3.22Å; P421-Y480 HydrophobicContact CB-CE2 3.67Å; P421-Y480 HydrophobicContact CG-CD1 4.26Å; P421-Y480 HydrophobicContact CG-CD2 3.67Å; P421-Y480 HydrophobicContact CG-CE1 3.87Å; P421-Y480 HydrophobicContact CG-CE2 3.19Å; P421-Y480 HydrophobicContact CG-CG 4.19Å
422	L	78.8	Confident	83.7	Confident	45 Å²	45	53.6 Å²	53.6	24%	0.236	26%	0.261	C	S	.	.	H	α-helix	trans	-73.7	-10.3	177.8	-58.6	175.2	0	0	0	114.5	K420 N426 L476	K420-L422 PolarHBondContact O-N 3.05Å; K420-L422 VanDerWaalsContact O-N 3.11Å; L422-N426 WeakPolarHBondContact O-CB 3.48Å; L422-N426 PolarHBondContact O-N 2.91Å; L422-N426 PolarHBondContact O-ND2 2.89Å; L422-N426 VanDerWaalsContact O-ND2 3.13Å; L422-L476 HydrophobicContact CD2-CB 4.15Å; L422-L476 HydrophobicContact CD2-CD2 4.01Å; L422-L476 HydrophobicContact CD2-CG 4.04Å
423	R	83.8	Confident	84.5	Confident	74 Å²	74	54.3 Å²	54.3	28%	0.279	27%	0.265	S	S	.	.	H	α-helix	trans	-64	-50.6	-175.4	-80.7	176.2	-157.4	-154.2	8.4	112.7	F416 K420 P421 L425 N426 L427	F416-R423 VanDerWaalsContact CD2-NH1 3.26Å; F416-R423 WeakPolarHBondContact O-CD 3.49Å; F416-R423 PolarHBondContact O-NH1 3.44Å; K420-R423 HydrophobicContact CB-CG 3.92Å; K420-R423 WeakPolarHBondContact O-CB 3.3Å; K420-R423 PolarHBondContact O-N 3.03Å; P421-R423 VanDerWaalsContact C-N 3.3Å; P421-R423 PolarHBondContact O-N 3.22Å; R423-L425 VanDerWaalsContact C-N 3.33Å; R423-N426 PolarHBondContact O-N 2.82Å; R423-L427 WeakPolarHBondContact O-CB 3.44Å; R423-L427 PolarHBondContact O-N 3.24Å
424	I	84.9	Confident	85.1	Confident	26 Å²	26	49 Å²	49	13%	0.133	26%	0.256	C	S	.	.	H	α-helix	trans	-65.2	-43.1	-178.3	-63.6	175.7	0	0	0	109.9	F284 L341 L417 F418 L427 L428	F284-I424 HydrophobicContact CE2-CD1 4.37Å; F284-I424 HydrophobicContact CZ-CD1 4.44Å; L341-I424 HydrophobicContact CD2-CD1 4.19Å; L341-I424 HydrophobicContact CD2-CG2 3.82Å; L417-I424 HydrophobicContact CD1-CD1 4.46Å; L417-I424 HydrophobicContact CD1-CG1 4.14Å; L417-I424 HydrophobicContact CD2-CD1 4.39Å; L417-I424 HydrophobicContact CG-CD1 4.08Å; L417-I424 HydrophobicContact CG-CG1 4.26Å; F418-I424 HydrophobicContact CD1-CD1 3.8Å; F418-I424 HydrophobicContact CE1-CD1 3.33Å; F418-I424 HydrophobicContact CZ-CD1 4.3Å; I424-L427 WeakPolarHBondContact O-CB 3.15Å; I424-L427 PolarHBondContact O-N 3.13Å; I424-L428 WeakPolarHBondContact O-CB 3.44Å; I424-L428 PolarHBondContact O-N 2.83Å
425	L	84.6	Confident	85.6	Confident	29 Å²	29	49.1 Å²	49.1	15%	0.152	26%	0.258	C	S	.	.	H	α-helix	trans	-63.2	-42.8	177.2	-173.7	59.3	0	0	0	112.3	R423 L427 L428 I429 L469 R473 L476	R423-L425 VanDerWaalsContact C-N 3.33Å; L425-L427 VanDerWaalsContact C-N 3.33Å; L425-L427 PolarHBondContact O-N 3.46Å; L425-L428 PolarHBondContact O-N 3.14Å; L425-I429 HydrophobicContact CD1-CD1 4.39Å; L425-I429 HydrophobicContact CG-CD1 4.11Å; L425-I429 VanDerWaalsContact O-CG1 3.3Å; L425-I429 WeakPolarHBondContact O-CG1 3.43Å; L425-I429 PolarHBondContact O-N 3.48Å; L425-L469 HydrophobicContact CD1-CD2 4.22Å; L425-R473 VanDerWaalsContact CD2-CA 3.44Å; L425-R473 HydrophobicContact CD2-CB 3.61Å; L425-R473 HydrophobicContact CD2-CG 4.27Å; L425-R473 HydrophobicContact CG-CB 4.06Å; L425-L476 HydrophobicContact CD2-CD2 4.2Å
426	N	88.7	Confident	86.3	Confident	71 Å²	71	48.6 Å²	48.6	38%	0.38	26%	0.257	S	S	.	.	H	α-helix	trans	-65	-36.7	175.1	-71.8	-22.8	0	0	0	112.1	L422 R423 G430	L422-N426 WeakPolarHBondContact O-CB 3.48Å; L422-N426 PolarHBondContact O-N 2.91Å; L422-N426 PolarHBondContact O-ND2 2.89Å; L422-N426 VanDerWaalsContact O-ND2 3.13Å; R423-N426 PolarHBondContact O-N 2.82Å; N426-G430 PolarHBondContact O-N 3.23Å
427	L	90	Very high	86.8	Confident	112 Å²	112	48 Å²	48	59%	0.586	26%	0.258	S	S	*	.	H	α-helix	trans	-63.8	-44.2	174.4	-179.6	125.7	0	0	0	110.7	R423 I424 L425 G430 I431	R423-L427 WeakPolarHBondContact O-CB 3.44Å; R423-L427 PolarHBondContact O-N 3.24Å; I424-L427 WeakPolarHBondContact O-CB 3.15Å; I424-L427 PolarHBondContact O-N 3.13Å; L425-L427 VanDerWaalsContact C-N 3.33Å; L425-L427 PolarHBondContact O-N 3.46Å; L427-G430 PolarHBondContact O-N 2.92Å; L427-I431 HydrophobicContact CD2-CD1 3.8Å; L427-I431 HydrophobicContact CG-CD1 4.22Å; L427-I431 WeakPolarHBondContact O-CG1 3.3Å; L427-I431 PolarHBondContact O-N 3.38Å
428	L	89.9	Confident	87.4	Confident	13 Å²	13	49.2 Å²	49.2	7%	0.068	26%	0.259	C	S	.	.	H	α-helix	trans	-64	-44.8	178.7	-162.7	64.9	0	0	0	112.1	V334 M337 I424 L425 G430 I431 E432 L469	V334-L428 HydrophobicContact CB-CD1 4.08Å; V334-L428 HydrophobicContact CG1-CD1 3.9Å; V334-L428 HydrophobicContact CG1-CD2 4.38Å; V334-L428 HydrophobicContact CG1-CG 3.92Å; V334-L428 HydrophobicContact CG2-CD1 3.84Å; M337-L428 HydrophobicContact CB-CD1 4.1Å; M337-L428 HydrophobicContact CB-CD2 4.4Å; I424-L428 WeakPolarHBondContact O-CB 3.44Å; I424-L428 PolarHBondContact O-N 2.83Å; L425-L428 PolarHBondContact O-N 3.14Å; L428-G430 VanDerWaalsContact C-N 3.3Å; L428-G430 PolarHBondContact O-N 3.3Å; L428-I431 PolarHBondContact O-N 2.96Å; L428-E432 PolarHBondContact O-N 2.87Å; L428-L469 HydrophobicContact CD2-CD1 4.18Å; L428-L469 HydrophobicContact CD2-CD2 3.65Å; L428-L469 HydrophobicContact CG-CD1 4Å; L428-L469 HydrophobicContact CG-CD2 4.35Å
429	I	91	Very high	88	Confident	27 Å²	27	48.9 Å²	48.9	14%	0.138	26%	0.258	C	S	.	.	H	α-helix	trans	-61.4	-39.7	173.3	-69.1	165.5	0	0	0	111.1	L425 E432 S433 L466 L469 R473	L425-I429 HydrophobicContact CD1-CD1 4.39Å; L425-I429 HydrophobicContact CG-CD1 4.11Å; L425-I429 VanDerWaalsContact O-CG1 3.3Å; L425-I429 WeakPolarHBondContact O-CG1 3.43Å; L425-I429 PolarHBondContact O-N 3.48Å; I429-E432 PolarHBondContact O-N 3.09Å; I429-S433 WeakPolarHBondContact O-CB 3.47Å; I429-S433 PolarHBondContact O-N 2.72Å; I429-L466 HydrophobicContact CG2-CD1 4.46Å; I429-L469 HydrophobicContact CD1-CB 4.43Å; I429-L469 HydrophobicContact CG1-CB 3.76Å; I429-L469 HydrophobicContact CG1-CD1 4.47Å; I429-R473 HydrophobicContact CD1-CB 3.54Å; I429-R473 HydrophobicContact CD1-CG 3.82Å
430	G	92.9	Very high	88.7	Confident	32 Å²	32	48.9 Å²	48.9	33%	0.33	26%	0.26	S	S	.	.	H	α-helix	trans	-62.9	-43.8	177.4	0	0	0	0	0	112.5	N426 L427 L428 S434	N426-G430 PolarHBondContact O-N 3.23Å; L427-G430 PolarHBondContact O-N 2.92Å; L428-G430 VanDerWaalsContact C-N 3.3Å; L428-G430 PolarHBondContact O-N 3.3Å; G430-S434 WeakPolarHBondContact O-CB 3.26Å; G430-S434 PolarHBondContact O-N 3.44Å; G430-S434 PolarHBondContact O-OG 3.38Å
431	I	93.1	Very high	89.3	Confident	54 Å²	54	49.5 Å²	49.5	28%	0.277	26%	0.259	S	S	.	.	H	α-helix	trans	-62.6	-51.6	175.6	-66.5	166.2	0	0	0	110	I330 V334 L427 L428 S433 S434 V435	I330-I431 HydrophobicContact CG2-CG2 3.46Å; I330-I431 VanDerWaalsContact CG2-CG2 3.46Å; V334-I431 HydrophobicContact CG2-CG2 3.97Å; L427-I431 HydrophobicContact CD2-CD1 3.8Å; L427-I431 HydrophobicContact CG-CD1 4.22Å; L427-I431 WeakPolarHBondContact O-CG1 3.3Å; L427-I431 PolarHBondContact O-N 3.38Å; L428-I431 PolarHBondContact O-N 2.96Å; I431-S433 PolarHBondContact O-N 3.08Å; I431-S434 WeakPolarHBondContact O-CB 3.43Å; I431-S434 PolarHBondContact O-N 3.43Å; I431-S434 VanDerWaalsContact O-N 3.14Å; I431-V435 WeakPolarHBondContact O-CG2 3.36Å; I431-V435 PolarHBondContact O-N 3.34Å
432	E	92.3	Very high	90.1	Very high	0 Å²	0	49.3 Å²	49.3	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-63.8	-44.2	-177.7	-172.2	58.7	-159.3	0	0	112.3	V334 L428 I429 S434 V435 V436 N462 V465 L466 L469	V334-E432 HydrophobicContact CG1-CB 4.27Å; V334-E432 HydrophobicContact CG1-CG 4.47Å; L428-E432 PolarHBondContact O-N 2.87Å; I429-E432 PolarHBondContact O-N 3.09Å; E432-S434 PolarHBondContact O-N 3.3Å; E432-V435 PolarHBondContact O-N 2.92Å; E432-V435 VanDerWaalsContact O-N 3.16Å; E432-V436 WeakPolarHBondContact O-CG2 3.3Å; E432-V436 PolarHBondContact O-N 2.78Å; E432-N462 WeakPolarHBondContact OE1-CB 3.1Å; E432-V465 HydrophobicContact CG-CG1 4.42Å; E432-L466 HydrophobicContact CB-CD1 4.35Å; E432-L466 HydrophobicContact CG-CB 4.06Å; E432-L466 HydrophobicContact CG-CD1 4.12Å; E432-L469 HydrophobicContact CB-CD1 4.21Å; E432-L469 HydrophobicContact CG-CD1 4.42Å
433	S	93.1	Very high	90.6	Very high	43 Å²	43	49.2 Å²	49.2	30%	0.301	26%	0.258	S	S	.	.	H	α-helix	trans	-61.2	-36	175.3	-176	0	0	0	0	111.7	I429 I431 L437	I429-S433 WeakPolarHBondContact O-CB 3.47Å; I429-S433 PolarHBondContact O-N 2.72Å; I431-S433 PolarHBondContact O-N 3.08Å; S433-L437 WeakPolarHBondContact O-CB 3.31Å; S433-L437 WeakPolarHBondContact O-CG 3.15Å; S433-L437 PolarHBondContact O-N 3.13Å
434	S	93.9	Very high	90.8	Very high	76 Å²	76	52.6 Å²	52.6	53%	0.531	28%	0.281	S	S	.	.	H	α-helix	trans	-67.2	-39.5	176.8	-58.6	0	0	0	0	111.3	G430 I431 E432 Y438	G430-S434 WeakPolarHBondContact O-CB 3.26Å; G430-S434 PolarHBondContact O-N 3.44Å; G430-S434 PolarHBondContact O-OG 3.38Å; I431-S434 WeakPolarHBondContact O-CB 3.43Å; I431-S434 PolarHBondContact O-N 3.43Å; I431-S434 VanDerWaalsContact O-N 3.14Å; E432-S434 PolarHBondContact O-N 3.3Å; S434-Y438 WeakPolarHBondContact O-CB 3.44Å; S434-Y438 PolarHBondContact O-N 2.83Å
435	V	93.1	Very high	91.1	Very high	13 Å²	13	60 Å²	60	8%	0.079	31%	0.307	C	S	.	.	H	α-helix	trans	-64.3	-48.2	175	173.7	0	0	0	0	111	I330 I431 E432 L437 Y438 Q439	I330-V435 HydrophobicContact CB-CG2 4.28Å; I330-V435 HydrophobicContact CD1-CG2 4.5Å; I330-V435 HydrophobicContact CG2-CG2 3.6Å; I431-V435 WeakPolarHBondContact O-CG2 3.36Å; I431-V435 PolarHBondContact O-N 3.34Å; E432-V435 PolarHBondContact O-N 2.92Å; E432-V435 VanDerWaalsContact O-N 3.16Å; V435-L437 VanDerWaalsContact C-N 3.35Å; V435-L437 PolarHBondContact O-N 2.98Å; V435-Y438 PolarHBondContact O-N 3.18Å; V435-Q439 HydrophobicContact CG1-CG 4.43Å; V435-Q439 WeakPolarHBondContact O-CB 3.41Å; V435-Q439 VanDerWaalsContact O-CG 3.32Å; V435-Q439 WeakPolarHBondContact O-CG 3.43Å; V435-Q439 PolarHBondContact O-N 2.74Å
436	V	93.7	Very high	91.1	Very high	9 Å²	9	59.7 Å²	59.7	6%	0.055	31%	0.308	C	S	.	.	H	α-helix	trans	-61.6	-42.1	178.4	170.6	0	0	0	0	111.4	E432 Q439 L440 L459 N462 Y463 L466	E432-V436 WeakPolarHBondContact O-CG2 3.3Å; E432-V436 PolarHBondContact O-N 2.78Å; V436-Q439 PolarHBondContact O-N 3.18Å; V436-L440 WeakPolarHBondContact O-CB 3.31Å; V436-L440 PolarHBondContact O-N 3.05Å; V436-L459 HydrophobicContact CG1-CD1 3.92Å; V436-N462 HydrophobicContact CG2-CB 3.94Å; V436-Y463 HydrophobicContact CG1-CD1 4.46Å; V436-Y463 HydrophobicContact CG1-CE1 3.89Å; V436-L466 HydrophobicContact CG1-CD2 4.46Å; V436-L466 HydrophobicContact CG2-CD2 4.31Å
437	L	93.7	Very high	90.7	Very high	106 Å²	106	65.6 Å²	65.6	56%	0.555	33%	0.333	S	S	*	.	H	α-helix	trans	-64	-42.4	175.8	-74.8	170.8	0	0	0	112	S433 V435 L440 Y441	S433-L437 WeakPolarHBondContact O-CB 3.31Å; S433-L437 WeakPolarHBondContact O-CG 3.15Å; S433-L437 PolarHBondContact O-N 3.13Å; V435-L437 VanDerWaalsContact C-N 3.35Å; V435-L437 PolarHBondContact O-N 2.98Å; L437-L440 PolarHBondContact O-N 3.47Å; L437-Y441 WeakPolarHBondContact O-CB 3.33Å; L437-Y441 PolarHBondContact O-N 2.92Å
438	Y	91.9	Very high	90.4	Very high	88 Å²	88	65.8 Å²	65.8	35%	0.345	33%	0.326	S	S	.	.	H	α-helix	trans	-62.8	-43.7	175.2	172.7	-97.4	0	0	0	111.7	E323 M327 S434 V435 Y441 S442	E323-Y438 PolarHBondContact OE1-OH 3.48Å; E323-Y438 VanDerWaalsContact OE1-OH 3.13Å; E323-Y438 PolarHBondContact OE2-OH 3.25Å; M327-Y438 HydrophobicContact SD-CD1 4.07Å; M327-Y438 HydrophobicContact SD-CE1 3.9Å; S434-Y438 WeakPolarHBondContact O-CB 3.44Å; S434-Y438 PolarHBondContact O-N 2.83Å; V435-Y438 PolarHBondContact O-N 3.18Å; Y438-Y441 PolarHBondContact O-N 3.43Å; Y438-S442 VanDerWaalsContact O-CB 3.3Å; Y438-S442 WeakPolarHBondContact O-CB 3.46Å; Y438-S442 PolarHBondContact O-N 3.44Å
439	Q	91.6	Very high	90	Very high	0 Å²	0	68.5 Å²	68.5	0%	0	34%	0.335	C	S	.	.	H	α-helix	trans	-62.7	-42.5	176.7	-74.4	173.6	-18.1	0	0	112	M327 V435 V436 S442 L443 L455 I458 L459 N462	M327-Q439 HydrophobicContact SD-CG 3.66Å; V435-Q439 HydrophobicContact CG1-CG 4.43Å; V435-Q439 WeakPolarHBondContact O-CB 3.41Å; V435-Q439 VanDerWaalsContact O-CG 3.32Å; V435-Q439 WeakPolarHBondContact O-CG 3.43Å; V435-Q439 PolarHBondContact O-N 2.74Å; V436-Q439 PolarHBondContact O-N 3.18Å; Q439-S442 PolarHBondContact O-N 2.83Å; Q439-L443 VanDerWaalsContact O-CB 3.25Å; Q439-L443 WeakPolarHBondContact O-CB 3.4Å; Q439-L443 PolarHBondContact O-N 2.98Å; Q439-L455 HydrophobicContact CB-CD2 4.38Å; Q439-L455 HydrophobicContact CG-CD2 4.17Å; Q439-I458 VanDerWaalsContact NE2-CG2 3.29Å; Q439-L459 HydrophobicContact CB-CD1 3.97Å; Q439-N462 VanDerWaalsContact CD-ND2 3.3Å; Q439-N462 PolarHBondContact NE2-ND2 3.17Å; Q439-N462 PolarHBondContact OE1-ND2 3.34Å
440	L	91.4	Very high	89.5	Confident	67 Å²	67	67.5 Å²	67.5	35%	0.351	33%	0.33	S	S	.	.	H	α-helix	trans	-64.8	-43.8	176.1	-174.9	66.3	0	0	0	111.6	V436 L437 L443 L444	V436-L440 WeakPolarHBondContact O-CB 3.31Å; V436-L440 PolarHBondContact O-N 3.05Å; L437-L440 PolarHBondContact O-N 3.47Å; L440-L443 WeakPolarHBondContact O-CB 3.48Å; L440-L443 PolarHBondContact O-N 3.43Å; L440-L444 WeakPolarHBondContact O-CG 3.29Å; L440-L444 PolarHBondContact O-N 2.91Å
441	Y	91.8	Very high	89.2	Confident	136 Å²	136	67.1 Å²	67.1	53%	0.533	32%	0.32	S	S	.	.	H	α-helix	trans	-60.9	-45.8	174.9	171.7	-98.9	0	0	0	111.8	L437 Y438 L443 L444 R445	L437-Y441 WeakPolarHBondContact O-CB 3.33Å; L437-Y441 PolarHBondContact O-N 2.92Å; Y438-Y441 PolarHBondContact O-N 3.43Å; Y441-L443 VanDerWaalsContact C-N 3.3Å; Y441-L443 PolarHBondContact O-N 3.3Å; Y441-L444 PolarHBondContact O-N 2.92Å; Y441-R445 PolarHBondContact O-N 2.74Å; Y441-R445 PolarHBondContact OH-NH1 2.86Å
442	S	88	Confident	88.9	Confident	15 Å²	15	67.2 Å²	67.2	11%	0.105	32%	0.323	C	S	.	.	H	α-helix	trans	-65.1	-35.7	178.2	-166.4	0	0	0	0	111.6	Y438 Q439 R445 S446	Y438-S442 VanDerWaalsContact O-CB 3.3Å; Y438-S442 WeakPolarHBondContact O-CB 3.46Å; Y438-S442 PolarHBondContact O-N 3.44Å; Q439-S442 PolarHBondContact O-N 2.83Å; S442-R445 PolarHBondContact O-N 3.38Å; S442-S446 VanDerWaalsContact O-CB 3.3Å; S442-S446 WeakPolarHBondContact O-CB 3.28Å; S442-S446 PolarHBondContact O-N 3.02Å
443	L	89.4	Confident	88.6	Confident	43 Å²	43	70.8 Å²	70.8	23%	0.225	34%	0.342	C	S	.	.	H	α-helix	trans	-64.1	-44.3	176.1	-174.2	70.5	0	0	0	111.5	Q439 L440 Y441 R445 S446 T452 L455 L459	Q439-L443 VanDerWaalsContact O-CB 3.25Å; Q439-L443 WeakPolarHBondContact O-CB 3.4Å; Q439-L443 PolarHBondContact O-N 2.98Å; L440-L443 WeakPolarHBondContact O-CB 3.48Å; L440-L443 PolarHBondContact O-N 3.43Å; Y441-L443 VanDerWaalsContact C-N 3.3Å; Y441-L443 PolarHBondContact O-N 3.3Å; L443-R445 VanDerWaalsContact C-N 3.26Å; L443-R445 PolarHBondContact O-N 2.77Å; L443-S446 PolarHBondContact O-N 3.01Å; L443-T452 HydrophobicContact CD1-CG2 3.68Å; L443-T452 WeakPolarHBondContact CD1-O 3.15Å; L443-L455 HydrophobicContact CB-CD1 4.12Å; L443-L455 HydrophobicContact CD1-CB 3.91Å; L443-L455 HydrophobicContact CD1-CD1 4.44Å; L443-L459 HydrophobicContact CD2-CD2 4.19Å
444	L	88.8	Confident	88.3	Confident	145 Å²	145	68.8 Å²	68.8	76%	0.759	33%	0.328	S	S	*	.	H	α-helix	trans	-65.7	-29.1	177.8	-69.7	171.4	0	0	0	113	L440 Y441	L440-L444 WeakPolarHBondContact O-CG 3.29Å; L440-L444 PolarHBondContact O-N 2.91Å; Y441-L444 PolarHBondContact O-N 2.92Å
445	R	89.4	Confident	88	Confident	181 Å²	181	65.2 Å²	65.2	68%	0.683	30%	0.303	S	S	*	.	H	α-helix	trans	-88.6	-13	178.8	-170.3	174	173.4	-179.1	-3.1	113.1	Y441 S442 L443 E447	Y441-R445 PolarHBondContact O-N 2.74Å; Y441-R445 PolarHBondContact OH-NH1 2.86Å; S442-R445 PolarHBondContact O-N 3.38Å; L443-R445 VanDerWaalsContact C-N 3.26Å; L443-R445 PolarHBondContact O-N 2.77Å; R445-E447 PolarHBondContact O-N 3.4Å
446	S	85.9	Confident	87.9	Confident	23 Å²	23	66 Å²	66	16%	0.161	31%	0.314	C	S	.	.			trans	-77.9	111.3	-173.3	167.3	0	0	0	0	111.6	S442 L443 R448 H451 T452	S442-S446 VanDerWaalsContact O-CB 3.3Å; S442-S446 WeakPolarHBondContact O-CB 3.28Å; S442-S446 PolarHBondContact O-N 3.02Å; L443-S446 PolarHBondContact O-N 3.01Å; S446-R448 PolarHBondContact OG-O 3.4Å; S446-H451 WeakPolarHBondContact OG-CB 3.12Å; S446-T452 PolarHBondContact OG-N 3.21Å; S446-T452 PolarHBondContact OG-OG1 3.05Å
447	E	80.1	Confident	87.7	Confident	195 Å²	195	68.4 Å²	68.4	91%	0.911	33%	0.326	S	S	*	.			trans	-85	-17	173.4	-63.8	178.8	176.6	0	0	113	R445	R445-E447 PolarHBondContact O-N 3.4Å
448	R	82.6	Confident	87.5	Confident	116 Å²	116	63.5 Å²	63.5	44%	0.438	30%	0.3	S	S	.	.	S	Bend	trans	-92.2	135.5	-176.5	-62.5	-179.5	-174.3	171.4	-0.9	110.8	D317 S446 N450 H451 T452	D317-R448 IonicContact OD1-NH1 3.58Å; D317-R448 PolarHBondContact OD1-NH1 3.36Å; D317-R448 IonicContact OD2-CZ 3.85Å; D317-R448 IonicContact OD2-NH1 3.58Å; D317-R448 PolarHBondContact OD2-NH1 2.66Å; S446-R448 PolarHBondContact OG-O 3.4Å; R448-N450 VanDerWaalsContact C-N 3.32Å; R448-N450 PolarHBondContact O-N 3.42Å; R448-H451 HydrophobicContact CB-CB 4.3Å; R448-H451 PolarHBondContact O-N 3.18Å; R448-T452 PolarHBondContact O-N 3.26Å; R448-T452 PolarHBondContact O-OG1 3.29Å
449	W	82.9	Confident	87.5	Confident	70 Å²	70	59.9 Å²	59.9	27%	0.265	29%	0.287	S	S	.	.	H	α-helix	trans	-59.7	-40.1	179.1	75.4	-88.2	0	0	0	112.9	T97 W99 W100 H451 T452 L453	T97-W449 WeakPolarHBondContact O-CZ2 3.26Å; W99-W449 AromaticContact CD1-CH2 3.99Å; W99-W449 AromaticContact CD1-CZ2 3.8Å; W100-W449 AromaticContact CH2-CD1 3.19Å; W100-W449 HydrophobicContact CH2-CG 4.32Å; W100-W449 AromaticContact CH2-NE1 3.03Å; W100-W449 AromaticContact CZ3-CD1 3.32Å; W100-W449 HydrophobicContact CZ3-CD2 4.27Å; W100-W449 AromaticContact CZ3-CE2 3.54Å; W100-W449 HydrophobicContact CZ3-CG 4.12Å; W100-W449 HydrophobicContact CZ3-CZ2 4.12Å; W100-W449 AromaticContact CZ3-NE1 2.96Å; W449-H451 PolarHBondContact O-N 3.29Å; W449-T452 PolarHBondContact O-N 3.42Å; W449-L453 WeakPolarHBondContact O-CB 3.4Å; W449-L453 PolarHBondContact O-N 3.46Å
450	N	80.8	Confident	87.4	Confident	6 Å²	6	65.9 Å²	65.9	3%	0.032	32%	0.318	C	S	.	.	H	α-helix	trans	-59.6	-47.3	179.3	-71.3	-59.6	0	0	0	111.5	R96 R448 T452 L453 S454	R96-N450 WeakPolarHBondContact CB-ND2 3.48Å; R96-N450 VanDerWaalsContact CD-ND2 3.3Å; R96-N450 WeakPolarHBondContact CD-ND2 3.32Å; R448-N450 VanDerWaalsContact C-N 3.32Å; R448-N450 PolarHBondContact O-N 3.42Å; N450-T452 VanDerWaalsContact C-N 3.34Å; N450-L453 PolarHBondContact O-N 3.32Å; N450-S454 WeakPolarHBondContact O-CB 3.22Å; N450-S454 PolarHBondContact O-N 3.1Å; N450-S454 PolarHBondContact O-OG 3.23Å
451	H	85	Confident	87.2	Confident	23 Å²	23	64.1 Å²	64.1	11%	0.106	31%	0.311	C	S	.	.	H	α-helix	trans	-65	-43.3	-179.3	-68.4	-169.8	0	0	0	110	W320 S446 R448 W449 L453 S454 L455	W320-H451 AromaticContact CD1-CD2 3.93Å; W320-H451 AromaticContact CD2-CD2 3.97Å; W320-H451 AromaticContact CD2-CE1 3.93Å; W320-H451 AromaticContact CD2-CG 3.94Å; W320-H451 AromaticContact CD2-ND1 3.92Å; W320-H451 AromaticContact CE2-CD2 3.69Å; W320-H451 AromaticContact CE2-CG 3.6Å; W320-H451 AromaticContact CE3-ND1 3.89Å; W320-H451 AromaticContact CG-NE2 3.91Å; W320-H451 HydrophobicContact CH2-CB 3.69Å; W320-H451 AromaticContact CH2-CG 3.9Å; W320-H451 HydrophobicContact CZ2-CB 3.4Å; W320-H451 VanDerWaalsContact CZ2-CB 3.4Å; W320-H451 AromaticContact CZ2-CG 3.59Å; W320-H451 HydrophobicContact CZ3-CB 4.47Å; W320-H451 AromaticContact CZ3-ND1 3.93Å; W320-H451 AromaticContact NE1-CD2 3.67Å; S446-H451 WeakPolarHBondContact OG-CB 3.12Å; R448-H451 HydrophobicContact CB-CB 4.3Å; R448-H451 PolarHBondContact O-N 3.18Å; W449-H451 PolarHBondContact O-N 3.29Å; H451-L453 PolarHBondContact O-N 3.43Å; H451-S454 WeakPolarHBondContact CA-OG 3.32Å; H451-S454 PolarHBondContact O-N 3.18Å; H451-S454 PolarHBondContact O-OG 3.16Å; H451-L455 WeakPolarHBondContact O-CB 3.4Å; H451-L455 WeakPolarHBondContact O-CG 3.18Å; H451-L455 PolarHBondContact O-N 3.09Å
452	T	86.6	Confident	87.1	Confident	57 Å²	57	57.6 Å²	57.6	35%	0.35	29%	0.285	S	S	.	.	H	α-helix	trans	-60.7	-46.7	176.4	-48	0	0	0	0	112.4	L443 S446 R448 W449 N450 G456	L443-T452 HydrophobicContact CD1-CG2 3.68Å; L443-T452 WeakPolarHBondContact CD1-O 3.15Å; S446-T452 PolarHBondContact OG-N 3.21Å; S446-T452 PolarHBondContact OG-OG1 3.05Å; R448-T452 PolarHBondContact O-N 3.26Å; R448-T452 PolarHBondContact O-OG1 3.29Å; W449-T452 PolarHBondContact O-N 3.42Å; N450-T452 VanDerWaalsContact C-N 3.34Å; T452-G456 PolarHBondContact O-N 3.03Å
453	L	86.9	Confident	87.1	Confident	74 Å²	74	62 Å²	62	39%	0.387	30%	0.301	S	S	.	.	H	α-helix	trans	-70.4	-41.6	-179.6	-171.8	140.9	0	0	0	111.9	I92 W449 N450 H451 G456 L457	I92-L453 HydrophobicContact CD1-CD2 3.6Å; W449-L453 WeakPolarHBondContact O-CB 3.4Å; W449-L453 PolarHBondContact O-N 3.46Å; N450-L453 PolarHBondContact O-N 3.32Å; H451-L453 PolarHBondContact O-N 3.43Å; L453-G456 PolarHBondContact O-N 3.47Å; L453-L457 HydrophobicContact CD2-CD1 3.79Å; L453-L457 WeakPolarHBondContact O-CG 3.33Å; L453-L457 PolarHBondContact O-N 3.24Å; L453-L457 VanDerWaalsContact O-N 3.11Å
454	S	86.6	Confident	87.1	Confident	2 Å²	2	64.9 Å²	64.9	1%	0.014	31%	0.309	C	S	.	.	H	α-helix	trans	-59	-49	176	66	0	0	0	0	112.1	W320 N450 H451 I458	W320-S454 PolarHBondContact NE1-OG 2.75Å; N450-S454 WeakPolarHBondContact O-CB 3.22Å; N450-S454 PolarHBondContact O-N 3.1Å; N450-S454 PolarHBondContact O-OG 3.23Å; H451-S454 WeakPolarHBondContact CA-OG 3.32Å; H451-S454 PolarHBondContact O-N 3.18Å; H451-S454 PolarHBondContact O-OG 3.16Å; S454-I458 WeakPolarHBondContact O-CG1 3.44Å; S454-I458 PolarHBondContact O-N 3.14Å
455	L	88.5	Confident	87	Confident	1 Å²	1	58.4 Å²	58.4	1%	0.005	28%	0.275	C	S	.	.	H	α-helix	trans	-66.6	-43	176.9	-74.8	176.1	0	0	0	112	W320 M327 Q439 L443 H451 L457 I458 L459	W320-L455 HydrophobicContact CH2-CD1 3.53Å; W320-L455 HydrophobicContact CH2-CD2 4.31Å; W320-L455 HydrophobicContact CH2-CG 3.85Å; W320-L455 HydrophobicContact CZ2-CD1 3.96Å; W320-L455 HydrophobicContact CZ2-CD2 4.3Å; W320-L455 HydrophobicContact CZ2-CG 3.76Å; M327-L455 HydrophobicContact CE-CD2 4.15Å; M327-L455 HydrophobicContact SD-CD2 4.33Å; Q439-L455 HydrophobicContact CB-CD2 4.38Å; Q439-L455 HydrophobicContact CG-CD2 4.17Å; L443-L455 HydrophobicContact CB-CD1 4.12Å; L443-L455 HydrophobicContact CD1-CB 3.91Å; L443-L455 HydrophobicContact CD1-CD1 4.44Å; H451-L455 WeakPolarHBondContact O-CB 3.4Å; H451-L455 WeakPolarHBondContact O-CG 3.18Å; H451-L455 PolarHBondContact O-N 3.09Å; L455-L457 VanDerWaalsContact C-N 3.34Å; L455-L457 PolarHBondContact O-N 3.04Å; L455-I458 PolarHBondContact O-N 3.04Å; L455-L459 WeakPolarHBondContact O-CB 3.4Å; L455-L459 PolarHBondContact O-N 2.97Å
456	G	89.4	Confident	87	Confident	30 Å²	30	51.1 Å²	51.1	31%	0.309	25%	0.25	S	C	.	.	H	α-helix	trans	-58.7	-43	-179.9	0	0	0	0	0	113.2	T452 L453 L460	T452-G456 PolarHBondContact O-N 3.03Å; L453-G456 PolarHBondContact O-N 3.47Å; G456-L460 PolarHBondContact O-N 2.93Å; G456-L460 VanDerWaalsContact O-N 3.1Å
457	L	89.8	Confident	87.1	Confident	59 Å²	59	56.4 Å²	56.4	31%	0.309	27%	0.27	S	S	.	.	H	α-helix	trans	-67.7	-44.1	178.9	-71.9	176	0	0	0	112.7	V85 F88 V89 L453 L455	V85-L457 HydrophobicContact CG1-CB 3.99Å; F88-L457 HydrophobicContact CD1-CD1 4.28Å; F88-L457 HydrophobicContact CE1-CD1 4.3Å; V89-L457 HydrophobicContact CG2-CB 4Å; V89-L457 HydrophobicContact CG2-CD1 3.97Å; L453-L457 HydrophobicContact CD2-CD1 3.79Å; L453-L457 WeakPolarHBondContact O-CG 3.33Å; L453-L457 PolarHBondContact O-N 3.24Å; L453-L457 VanDerWaalsContact O-N 3.11Å; L455-L457 VanDerWaalsContact C-N 3.34Å; L455-L457 PolarHBondContact O-N 3.04Å
458	I	90.4	Very high	87.4	Confident	2 Å²	2	48.4 Å²	48.4	1%	0.01	23%	0.233	C	C	.	.	H	α-helix	trans	-67.8	-41.7	178	-62	167.4	0	0	0	110.4	Y82 V89 H324 Q439 S454 L455 L460 C461 N462	Y82-I458 HydrophobicContact CE2-CG2 4.49Å; V89-I458 HydrophobicContact CG1-CD1 3.92Å; V89-I458 HydrophobicContact CG1-CG1 4.42Å; V89-I458 HydrophobicContact CG2-CG1 4.27Å; H324-I458 WeakPolarHBondContact CE1-CD1 3.47Å; H324-I458 WeakPolarHBondContact ND1-CD1 3.32Å; Q439-I458 VanDerWaalsContact NE2-CG2 3.29Å; S454-I458 WeakPolarHBondContact O-CG1 3.44Å; S454-I458 PolarHBondContact O-N 3.14Å; L455-I458 PolarHBondContact O-N 3.04Å; I458-L460 VanDerWaalsContact C-N 3.29Å; I458-L460 PolarHBondContact O-N 3.39Å; I458-C461 WeakPolarHBondContact O-CB 2.98Å; I458-C461 PolarHBondContact O-N 3.2Å; I458-C461 VanDerWaalsContact O-N 3.12Å; I458-N462 PolarHBondContact O-N 3.49Å; I458-N462 PolarHBondContact O-OD1 3.3Å
459	L	91.1	Very high	87.6	Confident	12 Å²	12	43.1 Å²	43.1	6%	0.063	21%	0.213	C	C	.	.	H	α-helix	trans	-60	-39.8	-180	-178	67.7	0	0	0	111.3	V436 Q439 L443 L455 C461 N462 Y463	V436-L459 HydrophobicContact CG1-CD1 3.92Å; Q439-L459 HydrophobicContact CB-CD1 3.97Å; L443-L459 HydrophobicContact CD2-CD2 4.19Å; L455-L459 WeakPolarHBondContact O-CB 3.4Å; L455-L459 PolarHBondContact O-N 2.97Å; L459-C461 VanDerWaalsContact C-N 3.34Å; L459-C461 PolarHBondContact O-N 3Å; L459-N462 PolarHBondContact O-N 3.27Å; L459-Y463 HydrophobicContact CD1-CD2 4.14Å; L459-Y463 HydrophobicContact CD1-CE2 3.66Å; L459-Y463 HydrophobicContact CD2-CE2 3.74Å; L459-Y463 HydrophobicContact CG-CD2 3.79Å; L459-Y463 HydrophobicContact CG-CE2 3.37Å; L459-Y463 WeakPolarHBondContact O-CD2 3.29Å; L459-Y463 PolarHBondContact O-N 3.07Å
460	L	89.4	Confident	87.8	Confident	127 Å²	127	43.3 Å²	43.3	67%	0.665	22%	0.219	S	C	*	.	H	α-helix	trans	-57.1	-46.2	174.2	-174.4	75.7	0	0	0	111.8	G456 I458	G456-L460 PolarHBondContact O-N 2.93Å; G456-L460 VanDerWaalsContact O-N 3.1Å; I458-L460 VanDerWaalsContact C-N 3.29Å; I458-L460 PolarHBondContact O-N 3.39Å
461	C	87.4	Confident	88.1	Confident	29 Å²	29	46.9 Å²	46.9	20%	0.196	23%	0.232	C	C	.	.	H	α-helix	trans	-65	-42.1	177.2	-64.8	0	0	0	0	111.7	Y82 I458 L459 Y463 Y464 V465	Y82-C461 HydrophobicContact CD2-CB 3.75Å; Y82-C461 HydrophobicContact CE2-CB 4.42Å; I458-C461 WeakPolarHBondContact O-CB 2.98Å; I458-C461 PolarHBondContact O-N 3.2Å; I458-C461 VanDerWaalsContact O-N 3.12Å; L459-C461 VanDerWaalsContact C-N 3.34Å; L459-C461 PolarHBondContact O-N 3Å; C461-Y463 PolarHBondContact O-N 3.48Å; C461-Y464 WeakPolarHBondContact O-CB 3.27Å; C461-Y464 PolarHBondContact O-N 3.2Å; C461-V465 PolarHBondContact O-N 3Å
462	N	89.2	Confident	87.9	Confident	0 Å²	0	46.8 Å²	46.8	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-67.8	-34.1	-178.6	-69.8	9.1	0	0	0	112.4	N331 E432 V436 Q439 I458 L459 Y464 V465 L466	N331-N462 VanDerWaalsContact CG-OD1 3.29Å; N331-N462 PolarHBondContact ND2-OD1 3.29Å; E432-N462 WeakPolarHBondContact OE1-CB 3.1Å; V436-N462 HydrophobicContact CG2-CB 3.94Å; Q439-N462 VanDerWaalsContact CD-ND2 3.3Å; Q439-N462 PolarHBondContact NE2-ND2 3.17Å; Q439-N462 PolarHBondContact OE1-ND2 3.34Å; I458-N462 PolarHBondContact O-N 3.49Å; I458-N462 PolarHBondContact O-OD1 3.3Å; L459-N462 PolarHBondContact O-N 3.27Å; N462-Y464 VanDerWaalsContact C-N 3.29Å; N462-Y464 PolarHBondContact O-N 2.88Å; N462-V465 PolarHBondContact O-N 3.03Å; N462-L466 WeakPolarHBondContact O-CB 3.3Å; N462-L466 PolarHBondContact O-N 3.39Å
463	Y	89.8	Confident	87.9	Confident	108 Å²	108	49.5 Å²	49.5	42%	0.424	24%	0.236	S	C	.	.	H	α-helix	trans	-59.6	-39.6	173.8	-86.5	-60.5	0	0	0	112.7	V436 L459 C461 L466 F467	V436-Y463 HydrophobicContact CG1-CD1 4.46Å; V436-Y463 HydrophobicContact CG1-CE1 3.89Å; L459-Y463 HydrophobicContact CD1-CD2 4.14Å; L459-Y463 HydrophobicContact CD1-CE2 3.66Å; L459-Y463 HydrophobicContact CD2-CE2 3.74Å; L459-Y463 HydrophobicContact CG-CD2 3.79Å; L459-Y463 HydrophobicContact CG-CE2 3.37Å; L459-Y463 WeakPolarHBondContact O-CD2 3.29Å; L459-Y463 PolarHBondContact O-N 3.07Å; C461-Y463 PolarHBondContact O-N 3.48Å; Y463-L466 PolarHBondContact O-N 3Å; Y463-F467 WeakPolarHBondContact O-CB 3.49Å; Y463-F467 PolarHBondContact O-N 3.09Å
464	Y	87.5	Confident	87.8	Confident	102 Å²	102	49.5 Å²	49.5	40%	0.4	24%	0.236	S	C	.	.	H	α-helix	trans	-63.2	-44.1	176.2	174.5	-94.2	0	0	0	111.5	L78 C461 N462 F467 K468	L78-Y464 HydrophobicContact CD1-CE1 3.69Å; L78-Y464 WeakPolarHBondContact CD1-OH 3.3Å; L78-Y464 HydrophobicContact CD2-CE1 4.37Å; C461-Y464 WeakPolarHBondContact O-CB 3.27Å; C461-Y464 PolarHBondContact O-N 3.2Å; N462-Y464 VanDerWaalsContact C-N 3.29Å; N462-Y464 PolarHBondContact O-N 2.88Å; Y464-F467 PolarHBondContact O-N 3.3Å; Y464-K468 WeakPolarHBondContact O-CB 3.26Å; Y464-K468 PolarHBondContact O-N 3.5Å
465	V	87	Confident	87.6	Confident	9 Å²	9	51.7 Å²	51.7	6%	0.055	25%	0.248	C	C	.	.	H	α-helix	trans	-62.5	-47.1	177.6	179	0	0	0	0	110.8	V334 M335 E432 C461 N462 F467 K468 L469	V334-V465 HydrophobicContact CG1-CG1 3.97Å; M335-V465 HydrophobicContact CE-CG2 4.34Å; M335-V465 HydrophobicContact CG-CG1 4.14Å; M335-V465 HydrophobicContact CG-CG2 3.71Å; M335-V465 HydrophobicContact SD-CG2 3.96Å; E432-V465 HydrophobicContact CG-CG1 4.42Å; C461-V465 PolarHBondContact O-N 3Å; N462-V465 PolarHBondContact O-N 3.03Å; V465-F467 PolarHBondContact O-N 3Å; V465-K468 PolarHBondContact O-N 3.39Å; V465-L469 HydrophobicContact CG1-CD1 4.33Å; V465-L469 WeakPolarHBondContact O-CG 3.45Å; V465-L469 PolarHBondContact O-N 3.2Å
466	L	90	Very high	87	Confident	28 Å²	28	51.8 Å²	51.8	15%	0.147	25%	0.249	C	C	.	.	H	α-helix	trans	-60.3	-45.3	177.4	-177.9	62.9	0	0	0	111.9	I429 E432 V436 N462 Y463 K468 L469 L470	I429-L466 HydrophobicContact CG2-CD1 4.46Å; E432-L466 HydrophobicContact CB-CD1 4.35Å; E432-L466 HydrophobicContact CG-CB 4.06Å; E432-L466 HydrophobicContact CG-CD1 4.12Å; V436-L466 HydrophobicContact CG1-CD2 4.46Å; V436-L466 HydrophobicContact CG2-CD2 4.31Å; N462-L466 WeakPolarHBondContact O-CB 3.3Å; N462-L466 PolarHBondContact O-N 3.39Å; Y463-L466 PolarHBondContact O-N 3Å; L466-K468 VanDerWaalsContact C-N 3.33Å; L466-K468 PolarHBondContact O-N 3.12Å; L466-L469 PolarHBondContact O-N 3.21Å; L466-L470 VanDerWaalsContact O-CB 3.29Å; L466-L470 WeakPolarHBondContact O-CB 3.35Å; L466-L470 PolarHBondContact O-N 3.21Å
467	F	88.8	Confident	86.5	Confident	134 Å²	134	51.4 Å²	51.4	59%	0.588	25%	0.245	S	C	*	.	H	α-helix	trans	-58.8	-45.8	176.5	171.8	-101.2	0	0	0	111.5	Y463 Y464 V465 L470 R471	Y463-F467 WeakPolarHBondContact O-CB 3.49Å; Y463-F467 PolarHBondContact O-N 3.09Å; Y464-F467 PolarHBondContact O-N 3.3Å; V465-F467 PolarHBondContact O-N 3Å; F467-L470 PolarHBondContact O-N 3.37Å; F467-R471 WeakPolarHBondContact O-CB 3.35Å; F467-R471 PolarHBondContact O-N 2.89Å
468	K	85.3	Confident	86.1	Confident	28 Å²	28	54.5 Å²	54.5	12%	0.122	26%	0.256	C	S	.	.	H	α-helix	trans	-59.7	-49	177.6	-179.6	176.9	168.5	176.1	0	111.8	D70 Y464 V465 L466 L470 R471 D472	D70-K468 WeakPolarHBondContact OD2-CE 3.46Å; D70-K468 IonicContact OD2-NZ 3.62Å; D70-K468 PolarHBondContact OD2-NZ 2.99Å; Y464-K468 WeakPolarHBondContact O-CB 3.26Å; Y464-K468 PolarHBondContact O-N 3.5Å; V465-K468 PolarHBondContact O-N 3.39Å; L466-K468 VanDerWaalsContact C-N 3.33Å; L466-K468 PolarHBondContact O-N 3.12Å; K468-L470 VanDerWaalsContact C-N 3.31Å; K468-L470 PolarHBondContact O-N 2.83Å; K468-R471 WeakPolarHBondContact O-CB 3.32Å; K468-R471 PolarHBondContact O-N 3.1Å; K468-D472 VanDerWaalsContact O-CG 3.23Å; K468-D472 PolarHBondContact O-N 2.84Å
469	L	86.3	Confident	85.3	Confident	4 Å²	4	55.2 Å²	55.2	2%	0.021	26%	0.262	C	S	.	.	H	α-helix	trans	-61.5	-39.9	177.9	-68.6	177.5	0	0	0	112.4	V334 L425 L428 I429 E432 V465 L466 D472 R473	V334-L469 HydrophobicContact CG1-CD1 3.77Å; L425-L469 HydrophobicContact CD1-CD2 4.22Å; L428-L469 HydrophobicContact CD2-CD1 4.18Å; L428-L469 HydrophobicContact CD2-CD2 3.65Å; L428-L469 HydrophobicContact CG-CD1 4Å; L428-L469 HydrophobicContact CG-CD2 4.35Å; I429-L469 HydrophobicContact CD1-CB 4.43Å; I429-L469 HydrophobicContact CG1-CB 3.76Å; I429-L469 HydrophobicContact CG1-CD1 4.47Å; E432-L469 HydrophobicContact CB-CD1 4.21Å; E432-L469 HydrophobicContact CG-CD1 4.42Å; V465-L469 HydrophobicContact CG1-CD1 4.33Å; V465-L469 WeakPolarHBondContact O-CG 3.45Å; V465-L469 PolarHBondContact O-N 3.2Å; L466-L469 PolarHBondContact O-N 3.21Å; L469-D472 PolarHBondContact O-N 2.72Å; L469-R473 WeakPolarHBondContact O-CB 3.36Å; L469-R473 PolarHBondContact O-N 3.35Å
470	L	87.3	Confident	84.4	Confident	74 Å²	74	57 Å²	57	39%	0.387	27%	0.269	S	S	.	.	H	α-helix	trans	-70.4	-39.1	-178.9	-160.8	135.6	0	0	0	111.6	L466 F467 K468 R473 I474	L466-L470 VanDerWaalsContact O-CB 3.29Å; L466-L470 WeakPolarHBondContact O-CB 3.35Å; L466-L470 PolarHBondContact O-N 3.21Å; F467-L470 PolarHBondContact O-N 3.37Å; K468-L470 VanDerWaalsContact C-N 3.31Å; K468-L470 PolarHBondContact O-N 2.83Å; L470-R473 PolarHBondContact O-N 3.08Å; L470-I474 HydrophobicContact CD2-CD1 3.63Å; L470-I474 HydrophobicContact CD2-CG1 4.43Å; L470-I474 VanDerWaalsContact O-CG1 3.32Å; L470-I474 WeakPolarHBondContact O-CG1 3.44Å; L470-I474 PolarHBondContact O-N 3.19Å
471	R	87.3	Confident	83.3	Confident	81 Å²	81	54.6 Å²	54.6	31%	0.306	26%	0.262	S	S	.	.	H	α-helix	trans	-56.3	-52.3	170	178.3	-161.5	70.1	-176.8	2	110.5	F467 K468 R473 I474 V475	F467-R471 WeakPolarHBondContact O-CB 3.35Å; F467-R471 PolarHBondContact O-N 2.89Å; K468-R471 WeakPolarHBondContact O-CB 3.32Å; K468-R471 PolarHBondContact O-N 3.1Å; R471-R473 VanDerWaalsContact C-N 3.26Å; R471-R473 PolarHBondContact O-N 3.34Å; R471-I474 PolarHBondContact O-N 2.93Å; R471-I474 VanDerWaalsContact O-N 3.13Å; R471-V475 WeakPolarHBondContact O-CG2 3.34Å; R471-V475 PolarHBondContact O-N 3.48Å
472	D	81.4	Confident	81.9	Confident	22 Å²	22	61.5 Å²	61.5	12%	0.118	29%	0.285	C	S	.	.	H	α-helix	trans	-62.1	-37.3	-177.6	-63.9	-9.6	0	0	0	110.9	K468 L469 V475 L476	K468-D472 VanDerWaalsContact O-CG 3.23Å; K468-D472 PolarHBondContact O-N 2.84Å; L469-D472 PolarHBondContact O-N 2.72Å; D472-V475 PolarHBondContact O-N 3.22Å; D472-L476 WeakPolarHBondContact O-CB 3.24Å; D472-L476 PolarHBondContact O-N 3.35Å
473	R	85.8	Confident	79.9	Confident	114 Å²	114	66.6 Å²	66.6	43%	0.43	32%	0.318	S	S	.	.	H	α-helix	trans	-66.2	-39.4	174.4	179	-97.5	-175.5	165.9	-2.3	113.5	L425 I429 L469 L470 R471 G477	L425-R473 VanDerWaalsContact CD2-CA 3.44Å; L425-R473 HydrophobicContact CD2-CB 3.61Å; L425-R473 HydrophobicContact CD2-CG 4.27Å; L425-R473 HydrophobicContact CG-CB 4.06Å; I429-R473 HydrophobicContact CD1-CB 3.54Å; I429-R473 HydrophobicContact CD1-CG 3.82Å; L469-R473 WeakPolarHBondContact O-CB 3.36Å; L469-R473 PolarHBondContact O-N 3.35Å; L470-R473 PolarHBondContact O-N 3.08Å; R471-R473 VanDerWaalsContact C-N 3.26Å; R471-R473 PolarHBondContact O-N 3.34Å; R473-G477 WeakPolarHBondContact O-CA 3.49Å; R473-G477 PolarHBondContact O-N 3.01Å
474	I	85.1	Confident	77.7	Confident	74 Å²	74	67.7 Å²	67.7	38%	0.379	33%	0.331	S	S	.	.	H	α-helix	trans	-66.8	-44.3	177.3	-70.1	167.6	0	0	0	110.1	L470 R471 G477 K478	L470-I474 HydrophobicContact CD2-CD1 3.63Å; L470-I474 HydrophobicContact CD2-CG1 4.43Å; L470-I474 VanDerWaalsContact O-CG1 3.32Å; L470-I474 WeakPolarHBondContact O-CG1 3.44Å; L470-I474 PolarHBondContact O-N 3.19Å; R471-I474 PolarHBondContact O-N 2.93Å; R471-I474 VanDerWaalsContact O-N 3.13Å; I474-G477 PolarHBondContact O-N 3.45Å; I474-K478 HydrophobicContact CG2-CD 4.46Å; I474-K478 WeakPolarHBondContact O-CB 3.46Å; I474-K478 WeakPolarHBondContact O-CG 3.41Å; I474-K478 PolarHBondContact O-N 3.35Å
475	V	82.8	Confident	75.1	Confident	47 Å²	47	66.7 Å²	66.7	29%	0.285	34%	0.339	S	S	.	.	H	α-helix	trans	-66.6	-48.1	-179.5	179.6	0	0	0	0	110.8	L67 R471 D472 G477 K478 A479	L67-V475 HydrophobicContact CD1-CG1 4.16Å; L67-V475 HydrophobicContact CD2-CB 3.82Å; L67-V475 HydrophobicContact CD2-CG1 3.5Å; L67-V475 VanDerWaalsContact CD2-CG1 3.5Å; L67-V475 HydrophobicContact CD2-CG2 4.03Å; L67-V475 HydrophobicContact CG-CG1 3.93Å; R471-V475 WeakPolarHBondContact O-CG2 3.34Å; R471-V475 PolarHBondContact O-N 3.48Å; D472-V475 PolarHBondContact O-N 3.22Å; V475-G477 VanDerWaalsContact C-N 3.33Å; V475-G477 PolarHBondContact O-N 3.33Å; V475-K478 PolarHBondContact O-N 3.28Å; V475-A479 PolarHBondContact O-N 3.09Å
476	L	75.9	Confident	72.7	Confident	4 Å²	4	70.7 Å²	70.7	2%	0.021	37%	0.367	C	S	.	.	H	α-helix	trans	-65.6	-38.6	178.8	-163.6	63	0	0	0	111.4	I64 L422 L425 D472 A479 Y480	I64-L476 HydrophobicContact CD1-CD1 3.86Å; I64-L476 HydrophobicContact CG2-CD1 4.18Å; L422-L476 HydrophobicContact CD2-CB 4.15Å; L422-L476 HydrophobicContact CD2-CD2 4.01Å; L422-L476 HydrophobicContact CD2-CG 4.04Å; L425-L476 HydrophobicContact CD2-CD2 4.2Å; D472-L476 WeakPolarHBondContact O-CB 3.24Å; D472-L476 PolarHBondContact O-N 3.35Å; L476-A479 PolarHBondContact O-N 3.4Å; L476-Y480 HydrophobicContact CD1-CD2 4.04Å; L476-Y480 HydrophobicContact CD1-CE2 3.43Å; L476-Y480 VanDerWaalsContact CD1-CE2 3.43Å; L476-Y480 HydrophobicContact CD2-CE2 4.16Å; L476-Y480 HydrophobicContact CG-CD2 3.83Å; L476-Y480 HydrophobicContact CG-CE2 3.53Å; L476-Y480 WeakPolarHBondContact O-CD2 3.43Å; L476-Y480 PolarHBondContact O-N 2.93Å
477	G	78.9	Confident	70.1	Confident	21 Å²	21	76.5 Å²	76.5	22%	0.216	40%	0.399	C	S	.	.	H	α-helix	trans	-60.4	-44.4	173.4	0	0	0	0	0	112.4	R473 I474 V475 S481	R473-G477 WeakPolarHBondContact O-CA 3.49Å; R473-G477 PolarHBondContact O-N 3.01Å; I474-G477 PolarHBondContact O-N 3.45Å; V475-G477 VanDerWaalsContact C-N 3.33Å; V475-G477 PolarHBondContact O-N 3.33Å; G477-S481 WeakPolarHBondContact O-CB 3.5Å; G477-S481 PolarHBondContact O-N 3.05Å; G477-S481 PolarHBondContact O-OG 3.25Å
478	K	80.4	Confident	67.5	Low	125 Å²	125	75.8 Å²	75.8	54%	0.543	41%	0.41	S	S	.	.	H	α-helix	trans	-61.2	-48.7	173.9	-78.9	-177.6	178.5	175.4	0	111.2	I474 V475 Y480 S481 Y482	I474-K478 HydrophobicContact CG2-CD 4.46Å; I474-K478 WeakPolarHBondContact O-CB 3.46Å; I474-K478 WeakPolarHBondContact O-CG 3.41Å; I474-K478 PolarHBondContact O-N 3.35Å; V475-K478 PolarHBondContact O-N 3.28Å; K478-Y480 VanDerWaalsContact C-N 3.32Å; K478-Y480 PolarHBondContact O-N 2.72Å; K478-S481 VanDerWaalsContact CA-OG 3.31Å; K478-S481 WeakPolarHBondContact CA-OG 3.46Å; K478-S481 PolarHBondContact O-N 3.32Å; K478-S481 PolarHBondContact O-OG 2.95Å; K478-Y482 HydrophobicContact CB-CE2 4.47Å; K478-Y482 WeakPolarHBondContact O-CD2 3.36Å; K478-Y482 PolarHBondContact O-N 3.33Å; K478-Y482 VanDerWaalsContact O-N 3.16Å
479	A	74.3	Confident	65.1	Low	17 Å²	17	79.7 Å²	79.7	14%	0.14	44%	0.441	C	S	.	.	H	α-helix	trans	-57.1	-40.6	-179.3	0	0	0	0	0	113.3	I64 V475 L476	I64-A479 HydrophobicContact CG1-CB 4.45Å; I64-A479 HydrophobicContact CG2-CB 4.12Å; V475-A479 PolarHBondContact O-N 3.09Å; L476-A479 PolarHBondContact O-N 3.4Å
480	Y	71.5	Confident	62.6	Low	50 Å²	50	82.7 Å²	82.7	20%	0.196	47%	0.473	C	S	.	.	H	α-helix	trans	-83.9	-17.8	176.2	-69.8	-65.5	0	0	0	114	S62 I64 D347 P421 L476 K478	S62-Y480 VanDerWaalsContact OG-CD1 3.31Å; S62-Y480 WeakPolarHBondContact OG-CD1 3.48Å; S62-Y480 WeakPolarHBondContact OG-CE1 3.15Å; I64-Y480 HydrophobicContact CD1-CE1 4.4Å; I64-Y480 HydrophobicContact CD1-CE2 4.22Å; I64-Y480 WeakPolarHBondContact CD1-OH 3.45Å; D347-Y480 PolarHBondContact OD1-OH 2.8Å; P421-Y480 HydrophobicContact CB-CE2 3.67Å; P421-Y480 HydrophobicContact CG-CD1 4.26Å; P421-Y480 HydrophobicContact CG-CD2 3.67Å; P421-Y480 HydrophobicContact CG-CE1 3.87Å; P421-Y480 HydrophobicContact CG-CE2 3.19Å; P421-Y480 HydrophobicContact CG-CG 4.19Å; L476-Y480 HydrophobicContact CD1-CD2 4.04Å; L476-Y480 HydrophobicContact CD1-CE2 3.43Å; L476-Y480 VanDerWaalsContact CD1-CE2 3.43Å; L476-Y480 HydrophobicContact CD2-CE2 4.16Å; L476-Y480 HydrophobicContact CG-CD2 3.83Å; L476-Y480 HydrophobicContact CG-CE2 3.53Å; L476-Y480 WeakPolarHBondContact O-CD2 3.43Å; L476-Y480 PolarHBondContact O-N 2.93Å; K478-Y480 VanDerWaalsContact C-N 3.32Å; K478-Y480 PolarHBondContact O-N 2.72Å
481	S	67.8	Low	59.9	Low	76 Å²	76	88.1 Å²	88.1	53%	0.531	50%	0.501	S	S	.	.	H	α-helix	trans	-84.4	-14.2	177.9	71.9	0	0	0	0	114.5	G477 K478 P483	G477-S481 WeakPolarHBondContact O-CB 3.5Å; G477-S481 PolarHBondContact O-N 3.05Å; G477-S481 PolarHBondContact O-OG 3.25Å; K478-S481 VanDerWaalsContact CA-OG 3.31Å; K478-S481 WeakPolarHBondContact CA-OG 3.46Å; K478-S481 PolarHBondContact O-N 3.32Å; K478-S481 PolarHBondContact O-OG 2.95Å; S481-P483 WeakPolarHBondContact O-CD 3.43Å
482	Y	56.5	Low	57.3	Low	173 Å²	173	93.6 Å²	93.6	68%	0.678	53%	0.527	S	S	*	.	S	Bend	trans	-83.3	91.4	164	-72.2	-77.4	0	0	0	107.3	K478 L484	K478-Y482 HydrophobicContact CB-CE2 4.47Å; K478-Y482 WeakPolarHBondContact O-CD2 3.36Å; K478-Y482 PolarHBondContact O-N 3.33Å; K478-Y482 VanDerWaalsContact O-N 3.16Å; Y482-L484 PolarHBondContact O-N 3.25Å
483	P	47.1	Very low	54.9	Low	107 Å²	107	98 Å²	98	70%	0.695	56%	0.559	S	S	*	*			trans	-55	139.3	156.4	28.1	-32.9	0	0	0	106	S481 S485	S481-P483 WeakPolarHBondContact O-CD 3.43Å; P483-S485 PolarHBondContact O-N 3.42Å
484	L	45.3	Very low	52.4	Low	131 Å²	131	105.1 Å²	105.1	69%	0.686	60%	0.598	S	S	*	*			trans	-49.2	96.7	165	-83.1	151.4	0	0	0	107.3	Y482 S486	Y482-L484 PolarHBondContact O-N 3.25Å; L484-S486 PolarHBondContact O-N 3.32Å
485	S	32.6	Very low	50.7	Low	82 Å²	82	106.7 Å²	106.7	57%	0.573	61%	0.608	S	S	*	*			trans	-52.2	133.3	163.6	148.2	0	0	0	0	105.6	P483 N487	P483-S485 PolarHBondContact O-N 3.42Å; S485-N487 PolarHBondContact O-N 3Å
486	S	36.4	Very low	49.1	Very low	93 Å²	93	109.8 Å²	109.8	65%	0.65	63%	0.625	S	S	*	*			trans	-60.5	57.5	-179	56.6	0	0	0	0	113.6	L484 S488	L484-S486 PolarHBondContact O-N 3.32Å; S486-S488 VanDerWaalsContact C-N 3.32Å; S486-S488 PolarHBondContact O-N 3.14Å
487	N	35.1	Very low	47.6	Very low	150 Å²	150	115.7 Å²	115.7	80%	0.802	66%	0.659	S	S	*	*	T	Hydrogen-bonded Turn	trans	-98.2	49.6	175.9	-84.5	6.4	0	0	0	111.9	S485	S485-N487 PolarHBondContact O-N 3Å
488	S	33.3	Very low	45.7	Very low	119 Å²	119	121.2 Å²	121.2	83%	0.832	69%	0.685	S	S	*	*	T	Hydrogen-bonded Turn	trans	-131	17.9	156.9	68.2	0	0	0	0	113.1	S486 G490	S486-S488 VanDerWaalsContact C-N 3.32Å; S486-S488 PolarHBondContact O-N 3.14Å; S488-G490 PolarHBondContact O-N 3.18Å
489	S	35.7	Very low	43.5	Very low	109 Å²	109	121 Å²	121	76%	0.762	69%	0.694	S	S	*	*	S	Bend	trans	-86.4	95.3	162.2	56.3	0	0	0	0	109.8
490	G	34.3	Very low	41.5	Very low	67 Å²	67	127.9 Å²	127.9	69%	0.691	73%	0.731	S	S	*	*			trans	120.6	62.5	152.9	0	0	0	0	0	117.7	S488 K492	S488-G490 PolarHBondContact O-N 3.18Å; G490-K492 VanDerWaalsContact C-N 3.32Å
491	L	29.9	Very low	39.3	Very low	188 Å²	188	133.5 Å²	133.5	98%	0.984	77%	0.769	S	S	*	*			trans	-91.4	81.9	136	-98.5	116.3	0	0	0	107.2
492	K	32.2	Very low	37.2	Very low	197 Å²	197	137.9 Å²	137.9	86%	0.857	79%	0.787	S	S	*	*			trans	-73.9	119.7	158.2	-98.5	-178.3	174.8	179.9	0	106.5	G490 Q494	G490-K492 VanDerWaalsContact C-N 3.32Å; K492-Q494 PolarHBondContact O-N 2.99Å
493	S	32.3	Very low	35.5	Very low	113 Å²	113	135 Å²	135	79%	0.79	80%	0.796	S	S	*	*			trans	-21	117.8	147.1	172.5	0	0	0	0	112.3
494	Q	32.4	Very low	34.5	Very low	264 Å²	264	137.5 Å²	137.5	100%	1.234	81%	0.806	S	S	*	*			trans	-139.7	0	134.5	-83.4	-162	-19.7	0	0	108	K492	K492-Q494 PolarHBondContact O-N 2.99Å

Retrieved 494 of 494 residues in 296.2 ms (Link to these results)

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