A0A087YFV4_POEFO Loading...

Solute carrier family 15 member 4

AlphaFold DB , UniProt , Accession A0A087YFV4, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 458 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	30.4	Very low	35.6	Very low	256 Å²	256	139.4 Å²	139.4	100%	1.261	73%	0.731	S	S	*	*				0	76.2	0	-135.5	171.6	-159.4	0	0	107.3
2	A	27.5	Very low	36.9	Very low	86 Å²	86	131.5 Å²	131.5	71%	0.711	71%	0.709	S	S	*	*			trans	-99.9	115.5	176	0	0	0	0	0	106.1	H4	A2-H4 PolarHBondContact O-N 3.01Å
3	S	26.4	Very low	37.9	Very low	119 Å²	119	134.1 Å²	134.1	83%	0.832	71%	0.713	S	S	*	*			trans	-58.2	100.7	178	44.4	0	0	0	0	110.1	P5	S3-P5 WeakPolarHBondContact O-CD 3.48Å
4	H	26.9	Very low	39	Very low	169 Å²	169	131 Å²	131	78%	0.782	69%	0.693	S	S	*	*			trans	-59.9	122.9	165.3	-77.5	-75.5	0	0	0	108.5	A2 I6	A2-H4 PolarHBondContact O-N 3.01Å; H4-I6 PolarHBondContact O-N 2.94Å; H4-I6 VanDerWaalsContact O-N 3.16Å
5	P	35.1	Very low	39.9	Very low	76 Å²	76	126.7 Å²	126.7	49%	0.494	67%	0.674	S	S	.	*			trans	-65.4	119.1	173.5	23.6	-28.9	0	0	0	109	S3 W7 I8	S3-P5 WeakPolarHBondContact O-CD 3.48Å; P5-W7 PolarHBondContact O-N 2.97Å; P5-I8 HydrophobicContact CG-CD1 4.27Å; P5-I8 PolarHBondContact O-N 3.47Å
6	I	32.5	Very low	40.4	Very low	144 Å²	144	120.2 Å²	120.2	74%	0.738	64%	0.643	S	S	*	*	G	3₁₀ helix	trans	-56.3	-11.3	179.9	-70.7	160.7	0	0	0	113.2	H4 I8	H4-I6 PolarHBondContact O-N 2.94Å; H4-I6 VanDerWaalsContact O-N 3.16Å; I6-I8 PolarHBondContact O-N 3.3Å
7	W	36.3	Very low	41.3	Very low	205 Å²	205	116.8 Å²	116.8	78%	0.777	62%	0.622	S	S	*	*	G	3₁₀ helix	trans	-65	-17.2	176	-64.6	93.7	0	0	0	115.2	P5	P5-W7 PolarHBondContact O-N 2.97Å
8	I	40.8	Very low	42	Very low	120 Å²	120	113.1 Å²	113.1	62%	0.615	61%	0.605	S	S	*	*	G	3₁₀ helix	trans	-80	-21.9	-176.8	-73.6	167.5	0	0	0	112.9	P5 I6	P5-I8 HydrophobicContact CG-CD1 4.27Å; P5-I8 PolarHBondContact O-N 3.47Å; I6-I8 PolarHBondContact O-N 3.3Å
9	H	41.3	Very low	42.7	Very low	186 Å²	186	108.5 Å²	108.5	86%	0.861	58%	0.582	S	S	*	*	S	Bend	trans	-88	-6.2	179.4	-81.5	-61.4	0	0	0	114.9
10	L	43.2	Very low	43.7	Very low	128 Å²	128	103.4 Å²	103.4	67%	0.67	55%	0.554	S	S	*	*	S	Bend	trans	-100.8	-5.2	179.2	-86.4	155.1	0	0	0	113.8
11	C	50.9	Low	44.5	Very low	44 Å²	44	100.4 Å²	100.4	30%	0.297	54%	0.54	S	S	.	.			trans	-144.8	120.1	-166	-68.5	0	0	0	0	112.2	C42	C11-C42 HydrophobicContact CB-CB 3.92Å; C11-C42 WeakPolarHBondContact CB-SG 3.34Å; C11-C42 WeakPolarHBondContact SG-CB 3.5Å; C11-C42 CovalentContact SG-SG 2.02Å; C11-C42 PolarHBondContact SG-SG 3.31Å
12	G	51.7	Low	46	Very low	45 Å²	45	89.1 Å²	89.1	46%	0.464	49%	0.488	S	S	.	.			trans	169.8	10.2	177	0	0	0	0	0	117.2
13	E	50.1	Low	47.7	Very low	165 Å²	165	89.2 Å²	89.2	77%	0.771	47%	0.474	S	S	*	.	S	Bend	trans	-85.8	-31.2	-167.7	-67.2	-176.2	156	0	0	114.7
14	E	52.3	Low	49.4	Very low	91 Å²	91	84.7 Å²	84.7	43%	0.425	44%	0.442	S	S	.	.	B	Isolated β-bridge	trans	-121.5	130.6	-171.9	-84.3	-81.9	156.4	0	0	111.8	P40 Y41	E14-P40 VanDerWaalsContact O-CA 3.23Å; E14-P40 WeakPolarHBondContact O-CA 3.38Å; E14-P40 WeakPolarHBondContact O-CB 3.46Å; E14-Y41 HydrophobicContact CB-CD1 4.25Å; E14-Y41 HydrophobicContact CB-CE1 3.69Å; E14-Y41 HydrophobicContact CB-CE2 4.2Å; E14-Y41 WeakPolarHBondContact O-CD1 3.11Å; E14-Y41 PolarHBondContact O-N 3.37Å; E14-Y41 VanDerWaalsContact O-N 3.09Å
15	T	53	Low	50.9	Low	66 Å²	66	81 Å²	81	41%	0.405	43%	0.426	S	S	.	.			trans	-76	131.9	177.8	55.2	0	0	0	0	110.6	F17	T15-F17 HydrophobicContact CG2-CE2 3.91Å; T15-F17 PolarHBondContact O-N 3.26Å; T15-F17 WeakPolarHBondContact OG1-CD2 3.18Å; T15-F17 WeakPolarHBondContact OG1-CE2 3.29Å
16	A	48.7	Very low	52	Low	23 Å²	23	82.6 Å²	82.6	19%	0.19	43%	0.43	C	S	.	.			trans	-82.4	79.4	-175.7	0	0	0	0	0	111.4	R38 Y41	A16-R38 HydrophobicContact CB-CB 3.98Å; A16-R38 WeakPolarHBondContact O-CD 3.45Å; A16-Y41 HydrophobicContact CB-CD1 3.94Å; A16-Y41 HydrophobicContact CB-CE1 4.49Å
17	F	55.6	Low	53.1	Low	62 Å²	62	84.4 Å²	84.4	27%	0.272	44%	0.442	S	S	.	.			trans	-120.6	124.4	179.6	-59.5	-48.6	0	0	0	115	T15 Q20 M25	T15-F17 HydrophobicContact CG2-CE2 3.91Å; T15-F17 PolarHBondContact O-N 3.26Å; T15-F17 WeakPolarHBondContact OG1-CD2 3.18Å; T15-F17 WeakPolarHBondContact OG1-CE2 3.29Å; F17-Q20 HydrophobicContact CB-CB 4.32Å; F17-Q20 HydrophobicContact CB-CG 4.47Å; F17-Q20 HydrophobicContact CD1-CB 4.06Å; F17-Q20 HydrophobicContact CD1-CG 3.34Å; F17-Q20 HydrophobicContact CD2-CB 4.17Å; F17-Q20 HydrophobicContact CD2-CG 4.16Å; F17-Q20 HydrophobicContact CE1-CG 3.61Å; F17-Q20 HydrophobicContact CE2-CG 4.28Å; F17-Q20 HydrophobicContact CG-CB 3.9Å; F17-Q20 HydrophobicContact CG-CG 3.71Å; F17-Q20 HydrophobicContact CZ-CG 4.08Å; F17-M25 HydrophobicContact CE2-SD 4.43Å
18	P	54.1	Low	54	Low	51 Å²	51	79.1 Å²	79.1	33%	0.331	44%	0.436	S	S	.	.	S	Bend	trans	-91.4	-27.1	155.5	-5.9	24.7	0	0	0	112.6	V326 F328 G409	P18-V326 HydrophobicContact CB-CG1 4.01Å; P18-V326 HydrophobicContact CG-CG1 3.86Å; P18-V326 HydrophobicContact CG-CG2 3.83Å; P18-F328 HydrophobicContact CB-CE1 4.36Å; P18-F328 HydrophobicContact CB-CZ 4.12Å; P18-G409 CarbonylContact O-C 3.37Å; P18-G409 VanDerWaalsContact O-C 3.29Å; P18-G409 WeakPolarHBondContact O-CA 3.28Å
19	V	54.1	Low	54.7	Low	26 Å²	26	77.6 Å²	77.6	16%	0.158	43%	0.432	C	S	.	.	S	Bend	trans	-150.5	123	174.3	-175.8	0	0	0	0	110.2	F328 F408 N410	V19-F328 HydrophobicContact CG2-CD1 4.08Å; V19-F328 HydrophobicContact CG2-CE1 4.24Å; V19-F408 CarbonylContact C-O 3.51Å; V19-F408 WeakPolarHBondContact CA-O 3.44Å; V19-N410 HydrophobicContact CG1-CB 3.99Å
20	Q	63.2	Low	55.5	Low	6 Å²	6	71.8 Å²	71.8	3%	0.028	41%	0.411	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-153.5	150.5	170.3	-100.8	-152.3	-3.6	0	0	115	F17 C24 P36 D407 F408	F17-Q20 HydrophobicContact CB-CB 4.32Å; F17-Q20 HydrophobicContact CB-CG 4.47Å; F17-Q20 HydrophobicContact CD1-CB 4.06Å; F17-Q20 HydrophobicContact CD1-CG 3.34Å; F17-Q20 HydrophobicContact CD2-CB 4.17Å; F17-Q20 HydrophobicContact CD2-CG 4.16Å; F17-Q20 HydrophobicContact CE1-CG 3.61Å; F17-Q20 HydrophobicContact CE2-CG 4.28Å; F17-Q20 HydrophobicContact CG-CB 3.9Å; F17-Q20 HydrophobicContact CG-CG 3.71Å; F17-Q20 HydrophobicContact CZ-CG 4.08Å; Q20-C24 VanDerWaalsContact OE1-CB 3.29Å; Q20-P36 HydrophobicContact CG-CG 4.13Å; Q20-P36 PolarHBondContact NE2-O 3.27Å; Q20-D407 CarbonylContact O-C 3.07Å; Q20-D407 WeakPolarHBondContact O-CA 3.38Å; Q20-F408 PolarHBondContact N-O 3.23Å; Q20-F408 PolarHBondContact O-N 3.09Å
21	P	61.3	Low	56.1	Low	40 Å²	40	70.8 Å²	70.8	26%	0.26	42%	0.421	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-60.8	140	170.2	-17.3	29.4	0	0	0	111.6	E23 C24 V33	P21-E23 WeakPolarHBondContact CB-OE2 3.22Å; P21-E23 PolarHBondContact O-N 2.93Å; P21-C24 WeakPolarHBondContact O-CB 3.32Å; P21-C24 PolarHBondContact O-N 3.22Å; P21-C24 VanDerWaalsContact O-N 3.09Å; P21-V33 HydrophobicContact CB-CG1 3.98Å; P21-V33 HydrophobicContact CG-CG1 3.93Å
22	A	62	Low	56.6	Low	20 Å²	20	76.3 Å²	76.3	17%	0.165	45%	0.448	C	S	.	.	G	3₁₀ helix	trans	-62.6	-26	178.8	0	0	0	0	0	113	C24 M25 H405 K406 F408	A22-C24 PolarHBondContact O-N 2.92Å; A22-M25 PolarHBondContact O-N 3.26Å; A22-H405 VanDerWaalsContact CB-O 3.26Å; A22-H405 WeakPolarHBondContact CB-O 3.4Å; A22-K406 VanDerWaalsContact CB-O 3.31Å; A22-K406 WeakPolarHBondContact CB-O 3.4Å; A22-K406 PolarHBondContact N-O 2.95Å; A22-F408 HydrophobicContact CB-CD2 4.43Å; A22-F408 HydrophobicContact CB-CE2 4.19Å
23	E	62.8	Low	57.1	Low	88 Å²	88	76.1 Å²	76.1	41%	0.411	44%	0.438	S	S	.	.	G	3₁₀ helix	trans	-66.9	-22	176.6	-56.7	99.4	177.6	0	0	113	P21 M25 N26 P30	P21-E23 WeakPolarHBondContact CB-OE2 3.22Å; P21-E23 PolarHBondContact O-N 2.93Å; E23-M25 PolarHBondContact O-N 3.46Å; E23-N26 PolarHBondContact O-N 3.45Å; E23-P30 HydrophobicContact CB-CG 4.37Å; E23-P30 HydrophobicContact CG-CG 4.31Å
24	C	61.8	Low	57.6	Low	24 Å²	24	75.8 Å²	75.8	16%	0.162	44%	0.439	C	S	.	.	G	3₁₀ helix	trans	-73.7	-9.8	177.1	-60.7	0	0	0	0	113.7	Q20 P21 A22 C35	Q20-C24 VanDerWaalsContact OE1-CB 3.29Å; P21-C24 WeakPolarHBondContact O-CB 3.32Å; P21-C24 PolarHBondContact O-N 3.22Å; P21-C24 VanDerWaalsContact O-N 3.09Å; A22-C24 PolarHBondContact O-N 2.92Å; C24-C35 WeakPolarHBondContact CA-SG 3.37Å; C24-C35 HydrophobicContact CB-CB 3.74Å; C24-C35 WeakPolarHBondContact CB-SG 3.47Å; C24-C35 WeakPolarHBondContact SG-CA 3.49Å; C24-C35 WeakPolarHBondContact SG-CB 3.46Å; C24-C35 CovalentContact SG-SG 2.03Å; C24-C35 PolarHBondContact SG-SG 3.05Å
25	M	58.8	Low	58	Low	92 Å²	92	73.1 Å²	73.1	45%	0.453	43%	0.431	S	S	.	.	G	3₁₀ helix	trans	-95.7	-9.8	176.6	-68.1	-84.3	-78	0	0	112.8	F17 A22 E23 F408	F17-M25 HydrophobicContact CE2-SD 4.43Å; A22-M25 PolarHBondContact O-N 3.26Å; E23-M25 PolarHBondContact O-N 3.46Å; M25-F408 HydrophobicContact CE-CE2 4.45Å; M25-F408 HydrophobicContact CE-CZ 4.41Å; M25-F408 HydrophobicContact CG-CD2 4.16Å; M25-F408 HydrophobicContact CG-CE2 4Å
26	N	58	Low	58.3	Low	108 Å²	108	73.4 Å²	73.4	58%	0.578	43%	0.433	S	S	*	.	S	Bend	trans	-98.2	145.4	177.2	-77.8	-16.7	0	0	0	110.7	E23 S28	E23-N26 PolarHBondContact O-N 3.45Å; N26-S28 PolarHBondContact O-N 3.15Å
27	N	54.4	Low	58.4	Low	183 Å²	183	83 Å²	83	98%	0.979	47%	0.465	S	S	*	.	S	Bend	trans	-62.8	-2.5	-179.9	-83.9	-7	0	0	0	115.2
28	S	55.7	Low	58.5	Low	93 Å²	93	84.5 Å²	84.5	65%	0.65	47%	0.469	S	S	*	.			trans	-124.5	91.5	178.7	57.9	0	0	0	0	109.5	N26	N26-S28 PolarHBondContact O-N 3.15Å
29	T	56.1	Low	58.7	Low	88 Å²	88	92.8 Å²	92.8	54%	0.54	49%	0.493	S	S	.	.			trans	-77.1	125.4	174.6	44.5	0	0	0	0	110.1
30	P	57.6	Low	59	Low	64 Å²	64	93.9 Å²	93.9	42%	0.416	50%	0.501	S	S	.	.			trans	-65.1	144.1	170	-15.9	28.9	0	0	0	110.6	E23 N32 V33	E23-P30 HydrophobicContact CB-CG 4.37Å; E23-P30 HydrophobicContact CG-CG 4.31Å; P30-N32 PolarHBondContact O-N 3.36Å; P30-V33 HydrophobicContact CB-CG2 4.32Å; P30-V33 HydrophobicContact CG-CG2 4.29Å; P30-V33 PolarHBondContact O-N 3.33Å; P30-V33 VanDerWaalsContact O-N 3.16Å
31	A	56.7	Low	59.2	Low	108 Å²	108	97 Å²	97	89%	0.893	51%	0.513	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.9	-13.1	-175.4	0	0	0	0	0	115.5
32	N	61.2	Low	59.7	Low	160 Å²	160	96.6 Å²	96.6	86%	0.856	51%	0.511	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.2	4	-177.8	-73.7	-9.3	0	0	0	114.4	P30	P30-N32 PolarHBondContact O-N 3.36Å
33	V	61.3	Low	60.3	Low	41 Å²	41	95.8 Å²	95.8	25%	0.248	50%	0.504	C	S	.	.			trans	-108.7	117.7	-178.5	-174.6	0	0	0	0	110.5	P21 P30 C35	P21-V33 HydrophobicContact CB-CG1 3.98Å; P21-V33 HydrophobicContact CG-CG1 3.93Å; P30-V33 HydrophobicContact CB-CG2 4.32Å; P30-V33 HydrophobicContact CG-CG2 4.29Å; P30-V33 PolarHBondContact O-N 3.33Å; P30-V33 VanDerWaalsContact O-N 3.16Å; V33-C35 PolarHBondContact O-N 3.38Å
34	I	60.9	Low	61.1	Low	158 Å²	158	94.2 Å²	94.2	81%	0.81	50%	0.503	S	S	*	.			trans	-81.7	107.5	172.8	-58.7	174.7	0	0	0	108	P36	I34-P36 VanDerWaalsContact O-CD 3.25Å; I34-P36 WeakPolarHBondContact O-CD 3.49Å
35	C	61.4	Low	62.1	Low	35 Å²	35	97.3 Å²	97.3	24%	0.236	52%	0.521	C	S	.	.			trans	-93.9	106.4	176.2	-64.7	0	0	0	0	110.4	C24 V33 W37	C24-C35 WeakPolarHBondContact CA-SG 3.37Å; C24-C35 HydrophobicContact CB-CB 3.74Å; C24-C35 WeakPolarHBondContact CB-SG 3.47Å; C24-C35 WeakPolarHBondContact SG-CA 3.49Å; C24-C35 WeakPolarHBondContact SG-CB 3.46Å; C24-C35 CovalentContact SG-SG 2.03Å; C24-C35 PolarHBondContact SG-SG 3.05Å; V33-C35 PolarHBondContact O-N 3.38Å; C35-W37 PolarHBondContact O-N 3.2Å
36	P	57.8	Low	63.3	Low	72 Å²	72	96.8 Å²	96.8	47%	0.468	52%	0.519	S	S	.	.			trans	-68.5	107.4	178.7	25	-31.3	0	0	0	110.3	Q20 I34 R38	Q20-P36 HydrophobicContact CG-CG 4.13Å; Q20-P36 PolarHBondContact NE2-O 3.27Å; I34-P36 VanDerWaalsContact O-CD 3.25Å; I34-P36 WeakPolarHBondContact O-CD 3.49Å; P36-R38 PolarHBondContact O-N 3.01Å
37	W	52.6	Low	64.6	Low	223 Å²	223	98 Å²	98	85%	0.845	52%	0.517	S	S	*	.			trans	-74.8	110.2	-179.4	-127.3	83.2	0	0	0	110.7	C35	C35-W37 PolarHBondContact O-N 3.2Å
38	R	57.6	Low	66.3	Low	95 Å²	95	94.3 Å²	94.3	36%	0.358	50%	0.496	S	S	.	.			trans	-104.6	140.2	166.2	-77.8	-168.9	177.3	-141.1	2.3	109.7	A16 P36 K325	A16-R38 HydrophobicContact CB-CB 3.98Å; A16-R38 WeakPolarHBondContact O-CD 3.45Å; P36-R38 PolarHBondContact O-N 3.01Å; R38-K325 VanDerWaalsContact NH2-CB 3.31Å; R38-K325 PolarHBondContact NH2-O 3.05Å
39	R	57.6	Low	67.9	Low	225 Å²	225	91.3 Å²	91.3	85%	0.849	48%	0.48	S	S	*	.			trans	-56.5	130.5	177.3	-69.4	-174	-177.3	-178.9	1.1	109.3
40	P	61.2	Low	69.5	Low	49 Å²	49	92.1 Å²	92.1	32%	0.318	48%	0.48	S	S	.	.			trans	-59.3	147.9	174.5	24.8	-32.9	0	0	0	110	E14	E14-P40 VanDerWaalsContact O-CA 3.23Å; E14-P40 WeakPolarHBondContact O-CA 3.38Å; E14-P40 WeakPolarHBondContact O-CB 3.46Å
41	Y	65.9	Low	71.2	Confident	71 Å²	71	93 Å²	93	28%	0.278	49%	0.485	S	S	.	.	B	Isolated β-bridge	trans	-107.7	155.8	-180	69.3	-83.7	0	0	0	110.5	E14 A16 G43 I46	E14-Y41 HydrophobicContact CB-CD1 4.25Å; E14-Y41 HydrophobicContact CB-CE1 3.69Å; E14-Y41 HydrophobicContact CB-CE2 4.2Å; E14-Y41 WeakPolarHBondContact O-CD1 3.11Å; E14-Y41 PolarHBondContact O-N 3.37Å; E14-Y41 VanDerWaalsContact O-N 3.09Å; A16-Y41 HydrophobicContact CB-CD1 3.94Å; A16-Y41 HydrophobicContact CB-CE1 4.49Å; Y41-G43 PolarHBondContact O-N 3.22Å; Y41-I46 HydrophobicContact CD2-CD1 3.43Å; Y41-I46 VanDerWaalsContact CD2-CD1 3.43Å; Y41-I46 HydrophobicContact CD2-CG1 4.38Å; Y41-I46 HydrophobicContact CE2-CD1 3.99Å; Y41-I46 HydrophobicContact CG-CD1 4.3Å
42	C	73.2	Confident	72.9	Confident	31 Å²	31	93.2 Å²	93.2	21%	0.209	47%	0.47	C	S	.	.			trans	-82.6	88.3	179.3	-13	0	0	0	0	108.6	C11 S44 V45 I46	C11-C42 HydrophobicContact CB-CB 3.92Å; C11-C42 WeakPolarHBondContact CB-SG 3.34Å; C11-C42 WeakPolarHBondContact SG-CB 3.5Å; C11-C42 CovalentContact SG-SG 2.02Å; C11-C42 PolarHBondContact SG-SG 3.31Å; C42-S44 VanDerWaalsContact C-N 3.29Å; C42-S44 PolarHBondContact O-N 3.39Å; C42-V45 HydrophobicContact CB-CB 4.03Å; C42-V45 HydrophobicContact CB-CG2 3.77Å; C42-V45 PolarHBondContact O-N 3.37Å; C42-I46 PolarHBondContact O-N 2.96Å
43	G	74.4	Confident	74.3	Confident	3 Å²	3	90 Å²	90	3%	0.031	46%	0.456	C	S	.	.	H	α-helix	trans	-54	-45.2	-179	0	0	0	0	0	112.4	Y41 V45 I46 Y47	Y41-G43 PolarHBondContact O-N 3.22Å; G43-V45 PolarHBondContact O-N 3.32Å; G43-I46 PolarHBondContact O-N 3.4Å; G43-Y47 WeakPolarHBondContact O-CD2 3.33Å; G43-Y47 PolarHBondContact O-N 3.09Å
44	S	78.9	Confident	75.7	Confident	56 Å²	56	91.1 Å²	91.1	39%	0.392	47%	0.469	S	S	.	.	H	α-helix	trans	-55.7	-47	177.4	56.9	0	0	0	0	113.3	C42 I46 Y47 I48	C42-S44 VanDerWaalsContact C-N 3.29Å; C42-S44 PolarHBondContact O-N 3.39Å; S44-I46 PolarHBondContact O-N 3.41Å; S44-Y47 PolarHBondContact O-N 3.22Å; S44-I48 WeakPolarHBondContact O-CB 3.46Å; S44-I48 WeakPolarHBondContact O-CD1 3.29Å; S44-I48 WeakPolarHBondContact O-CG1 3.23Å; S44-I48 PolarHBondContact O-N 3.48Å
45	V	83.7	Confident	77.1	Confident	88 Å²	88	88.8 Å²	88.8	53%	0.533	46%	0.458	S	S	.	.	H	α-helix	trans	-62.8	-43.2	178.4	179.5	0	0	0	0	110.9	C42 G43 G49	C42-V45 HydrophobicContact CB-CB 4.03Å; C42-V45 HydrophobicContact CB-CG2 3.77Å; C42-V45 PolarHBondContact O-N 3.37Å; G43-V45 PolarHBondContact O-N 3.32Å; V45-G49 PolarHBondContact O-N 3.2Å
46	I	82.9	Confident	78.4	Confident	82 Å²	82	88.7 Å²	88.7	42%	0.421	46%	0.463	S	S	.	.	H	α-helix	trans	-64.7	-47.9	178	-63.7	-174.3	0	0	0	110.5	Y41 C42 G43 S44 I48 G49 L50	Y41-I46 HydrophobicContact CD2-CD1 3.43Å; Y41-I46 VanDerWaalsContact CD2-CD1 3.43Å; Y41-I46 HydrophobicContact CD2-CG1 4.38Å; Y41-I46 HydrophobicContact CE2-CD1 3.99Å; Y41-I46 HydrophobicContact CG-CD1 4.3Å; C42-I46 PolarHBondContact O-N 2.96Å; G43-I46 PolarHBondContact O-N 3.4Å; S44-I46 PolarHBondContact O-N 3.41Å; I46-I48 PolarHBondContact O-N 3.39Å; I46-G49 PolarHBondContact O-N 3.41Å; I46-L50 HydrophobicContact CG2-CD1 3.91Å; I46-L50 HydrophobicContact CG2-CG 4.29Å; I46-L50 WeakPolarHBondContact O-CB 3.49Å; I46-L50 VanDerWaalsContact O-CG 3.31Å; I46-L50 WeakPolarHBondContact O-CG 3.26Å; I46-L50 PolarHBondContact O-N 3.17Å
47	Y	84.6	Confident	79.8	Confident	132 Å²	132	89.2 Å²	89.2	52%	0.518	47%	0.465	S	S	.	.	H	α-helix	trans	-64.5	-42	-179.6	-65.9	-48.3	0	0	0	112.3	G43 S44 G49 L50 V51	G43-Y47 WeakPolarHBondContact O-CD2 3.33Å; G43-Y47 PolarHBondContact O-N 3.09Å; S44-Y47 PolarHBondContact O-N 3.22Å; Y47-G49 VanDerWaalsContact C-N 3.34Å; Y47-G49 PolarHBondContact O-N 2.87Å; Y47-L50 HydrophobicContact CD1-CD1 4.48Å; Y47-L50 PolarHBondContact O-N 3.31Å; Y47-V51 VanDerWaalsContact O-CG2 3.31Å; Y47-V51 WeakPolarHBondContact O-CG2 3.41Å; Y47-V51 PolarHBondContact O-N 2.94Å
48	I	90	Very high	81.3	Confident	106 Å²	106	80.6 Å²	80.6	54%	0.544	45%	0.445	S	S	.	.	H	α-helix	trans	-60.4	-46.5	173.5	-69.5	166.4	0	0	0	110	S44 I46 L50 V51 L52	S44-I48 WeakPolarHBondContact O-CB 3.46Å; S44-I48 WeakPolarHBondContact O-CD1 3.29Å; S44-I48 WeakPolarHBondContact O-CG1 3.23Å; S44-I48 PolarHBondContact O-N 3.48Å; I46-I48 PolarHBondContact O-N 3.39Å; I48-L50 PolarHBondContact O-N 3.38Å; I48-V51 PolarHBondContact O-N 2.94Å; I48-L52 HydrophobicContact CG2-CD1 3.98Å; I48-L52 HydrophobicContact CG2-CG 4.37Å; I48-L52 WeakPolarHBondContact O-CB 3.38Å; I48-L52 VanDerWaalsContact O-CG 3.32Å; I48-L52 WeakPolarHBondContact O-CG 3.4Å; I48-L52 PolarHBondContact O-N 2.68Å
49	G	90.5	Very high	82.5	Confident	31 Å²	31	80.1 Å²	80.1	32%	0.32	45%	0.453	S	S	.	.	H	α-helix	trans	-57.5	-46.3	176	0	0	0	0	0	112.7	V45 I46 Y47 V51 L52 V53	V45-G49 PolarHBondContact O-N 3.2Å; I46-G49 PolarHBondContact O-N 3.41Å; Y47-G49 VanDerWaalsContact C-N 3.34Å; Y47-G49 PolarHBondContact O-N 2.87Å; G49-V51 PolarHBondContact O-N 3.12Å; G49-L52 PolarHBondContact O-N 3.47Å; G49-V53 VanDerWaalsContact O-CG2 3.32Å; G49-V53 WeakPolarHBondContact O-CG2 3.49Å; G49-V53 PolarHBondContact O-N 3.31Å
50	L	90	Very high	83.8	Confident	104 Å²	104	73.1 Å²	73.1	55%	0.545	44%	0.435	S	S	.	.	H	α-helix	trans	-63.4	-40.8	177.3	-71.7	172.8	0	0	0	112.3	I46 Y47 I48 V53 A54	I46-L50 HydrophobicContact CG2-CD1 3.91Å; I46-L50 HydrophobicContact CG2-CG 4.29Å; I46-L50 WeakPolarHBondContact O-CB 3.49Å; I46-L50 VanDerWaalsContact O-CG 3.31Å; I46-L50 WeakPolarHBondContact O-CG 3.26Å; I46-L50 PolarHBondContact O-N 3.17Å; Y47-L50 HydrophobicContact CD1-CD1 4.48Å; Y47-L50 PolarHBondContact O-N 3.31Å; I48-L50 PolarHBondContact O-N 3.38Å; L50-V53 PolarHBondContact O-N 3.47Å; L50-A54 WeakPolarHBondContact O-CB 3.41Å; L50-A54 PolarHBondContact O-N 2.92Å
51	V	91.8	Very high	84.7	Confident	84 Å²	84	76.8 Å²	76.8	51%	0.509	45%	0.446	S	S	.	.	H	α-helix	trans	-64.2	-43.7	175	169.4	0	0	0	0	110.9	Y47 I48 G49 A54 L55	Y47-V51 VanDerWaalsContact O-CG2 3.31Å; Y47-V51 WeakPolarHBondContact O-CG2 3.41Å; Y47-V51 PolarHBondContact O-N 2.94Å; I48-V51 PolarHBondContact O-N 2.94Å; G49-V51 PolarHBondContact O-N 3.12Å; V51-A54 PolarHBondContact O-N 3.19Å; V51-L55 HydrophobicContact CG1-CD1 4.07Å; V51-L55 HydrophobicContact CG1-CG 4.43Å; V51-L55 WeakPolarHBondContact O-CG 3.36Å; V51-L55 PolarHBondContact O-N 3.09Å
52	L	92.4	Very high	85.1	Confident	111 Å²	111	76.7 Å²	76.7	58%	0.581	46%	0.456	S	S	*	.	H	α-helix	trans	-62.9	-42.7	176.7	-71.9	174	0	0	0	111.8	I48 G49 L55 G56	I48-L52 HydrophobicContact CG2-CD1 3.98Å; I48-L52 HydrophobicContact CG2-CG 4.37Å; I48-L52 WeakPolarHBondContact O-CB 3.38Å; I48-L52 VanDerWaalsContact O-CG 3.32Å; I48-L52 WeakPolarHBondContact O-CG 3.4Å; I48-L52 PolarHBondContact O-N 2.68Å; G49-L52 PolarHBondContact O-N 3.47Å; L52-L55 PolarHBondContact O-N 2.96Å; L52-G56 PolarHBondContact O-N 3.16Å
53	V	91.5	Very high	85.4	Confident	93 Å²	93	80 Å²	80	56%	0.564	47%	0.472	S	S	*	.	H	α-helix	trans	-61.9	-44.5	173.8	170.7	0	0	0	0	110.5	G49 L50 L55 G56 V57	G49-V53 VanDerWaalsContact O-CG2 3.32Å; G49-V53 WeakPolarHBondContact O-CG2 3.49Å; G49-V53 PolarHBondContact O-N 3.31Å; L50-V53 PolarHBondContact O-N 3.47Å; V53-L55 PolarHBondContact O-N 3.07Å; V53-G56 PolarHBondContact O-N 3.36Å; V53-V57 HydrophobicContact CG1-CG2 4.24Å; V53-V57 WeakPolarHBondContact O-CB 3.25Å; V53-V57 VanDerWaalsContact O-CG2 3.31Å; V53-V57 WeakPolarHBondContact O-CG2 3.24Å; V53-V57 PolarHBondContact O-N 2.95Å
54	A	89.8	Confident	85.9	Confident	64 Å²	64	83.4 Å²	83.4	53%	0.529	49%	0.488	S	S	.	.	H	α-helix	trans	-61.5	-42.9	177.9	0	0	0	0	0	112.3	L50 V51 G58	L50-A54 WeakPolarHBondContact O-CB 3.41Å; L50-A54 PolarHBondContact O-N 2.92Å; V51-A54 PolarHBondContact O-N 3.19Å; A54-G58 PolarHBondContact O-N 2.97Å
55	L	90.1	Very high	86.1	Confident	109 Å²	109	82.6 Å²	82.6	57%	0.571	48%	0.481	S	S	*	.	H	α-helix	trans	-63	-44	174.3	-71.5	172.1	0	0	0	111.7	V51 L52 V53 G58 T59	V51-L55 HydrophobicContact CG1-CD1 4.07Å; V51-L55 HydrophobicContact CG1-CG 4.43Å; V51-L55 WeakPolarHBondContact O-CG 3.36Å; V51-L55 PolarHBondContact O-N 3.09Å; L52-L55 PolarHBondContact O-N 2.96Å; V53-L55 PolarHBondContact O-N 3.07Å; L55-G58 PolarHBondContact O-N 2.91Å; L55-T59 VanDerWaalsContact O-CG2 3.31Å; L55-T59 WeakPolarHBondContact O-CG2 3.5Å; L55-T59 PolarHBondContact O-N 3.31Å; L55-T59 PolarHBondContact O-OG1 3.31Å
56	G	90.1	Very high	85.8	Confident	34 Å²	34	81 Å²	81	35%	0.351	47%	0.473	S	S	.	.	H	α-helix	trans	-61.6	-47.6	176.2	0	0	0	0	0	112.6	L52 V53 G58 T59 V60	L52-G56 PolarHBondContact O-N 3.16Å; V53-G56 PolarHBondContact O-N 3.36Å; G56-G58 PolarHBondContact O-N 2.9Å; G56-T59 PolarHBondContact O-N 3.44Å; G56-T59 PolarHBondContact O-OG1 3.31Å; G56-V60 WeakPolarHBondContact O-CG2 3.15Å; G56-V60 PolarHBondContact O-N 3.41Å
57	V	87.8	Confident	86	Confident	83 Å²	83	80.1 Å²	80.1	50%	0.503	47%	0.465	S	S	.	.	H	α-helix	trans	-63.4	-44.3	177.4	172.5	0	0	0	0	110.9	V53 T59 V60 K61	V53-V57 HydrophobicContact CG1-CG2 4.24Å; V53-V57 WeakPolarHBondContact O-CB 3.25Å; V53-V57 VanDerWaalsContact O-CG2 3.31Å; V53-V57 WeakPolarHBondContact O-CG2 3.24Å; V53-V57 PolarHBondContact O-N 2.95Å; V57-T59 PolarHBondContact O-N 2.95Å; V57-V60 PolarHBondContact O-N 2.53Å; V57-K61 WeakPolarHBondContact O-CB 3.46Å; V57-K61 PolarHBondContact O-N 2.82Å
58	G	83.2	Confident	86.1	Confident	42 Å²	42	74.4 Å²	74.4	43%	0.433	45%	0.447	S	S	.	.	H	α-helix	trans	-61.5	-41.2	179.7	0	0	0	0	0	113.4	A54 L55 G56 S62	A54-G58 PolarHBondContact O-N 2.97Å; L55-G58 PolarHBondContact O-N 2.91Å; G56-G58 PolarHBondContact O-N 2.9Å; G58-S62 PolarHBondContact O-OG 3.26Å
59	T	82.4	Confident	85.9	Confident	84 Å²	84	70 Å²	70	52%	0.515	43%	0.426	S	S	.	.	H	α-helix	trans	-71.4	-42	178.7	52.3	0	0	0	0	112.5	L55 G56 V57 S62 N63	L55-T59 VanDerWaalsContact O-CG2 3.31Å; L55-T59 WeakPolarHBondContact O-CG2 3.5Å; L55-T59 PolarHBondContact O-N 3.31Å; L55-T59 PolarHBondContact O-OG1 3.31Å; G56-T59 PolarHBondContact O-N 3.44Å; G56-T59 PolarHBondContact O-OG1 3.31Å; V57-T59 PolarHBondContact O-N 2.95Å; T59-S62 PolarHBondContact O-OG 3.25Å; T59-N63 PolarHBondContact O-ND2 2.95Å
60	V	84.4	Confident	85.6	Confident	78 Å²	78	70.6 Å²	70.6	47%	0.473	42%	0.422	S	S	.	.	H	α-helix	trans	-72.9	-48	-179.6	175.6	0	0	0	0	111.3	G56 V57 S62 N63 I64	G56-V60 WeakPolarHBondContact O-CG2 3.15Å; G56-V60 PolarHBondContact O-N 3.41Å; V57-V60 PolarHBondContact O-N 2.53Å; V60-S62 VanDerWaalsContact C-N 3.28Å; V60-S62 PolarHBondContact O-N 3.49Å; V60-N63 PolarHBondContact O-N 3.45Å; V60-N63 VanDerWaalsContact O-N 3.13Å; V60-I64 HydrophobicContact CG1-CB 4.19Å; V60-I64 HydrophobicContact CG1-CD1 3.94Å; V60-I64 HydrophobicContact CG1-CG2 4.35Å; V60-I64 WeakPolarHBondContact O-CB 3.27Å; V60-I64 WeakPolarHBondContact O-CG2 3.43Å; V60-I64 PolarHBondContact O-N 3.46Å
61	K	80.2	Confident	85.7	Confident	127 Å²	127	67.5 Å²	67.5	55%	0.552	41%	0.405	S	S	*	.	H	α-helix	trans	-61	-34.6	-172.8	-171.1	174.2	-177.6	177	0	113.2	V57	V57-K61 WeakPolarHBondContact O-CB 3.46Å; V57-K61 PolarHBondContact O-N 2.82Å
62	S	75.2	Confident	85.6	Confident	68 Å²	68	64.9 Å²	64.9	48%	0.476	39%	0.389	S	S	.	.	H	α-helix	trans	-76.7	-25	179.7	51.8	0	0	0	0	113.9	G58 T59 V60	G58-S62 PolarHBondContact O-OG 3.26Å; T59-S62 PolarHBondContact O-OG 3.25Å; V60-S62 VanDerWaalsContact C-N 3.28Å; V60-S62 PolarHBondContact O-N 3.49Å
63	N	78.9	Confident	85.2	Confident	102 Å²	102	65.3 Å²	65.3	55%	0.545	39%	0.386	S	S	.	.	H	α-helix	trans	-109.7	-29.4	-171.1	-67.4	-66.1	0	0	0	114	T59 V60 T65 P66 F67	T59-N63 PolarHBondContact O-ND2 2.95Å; V60-N63 PolarHBondContact O-N 3.45Å; V60-N63 VanDerWaalsContact O-N 3.13Å; N63-T65 PolarHBondContact O-N 2.9Å; N63-P66 WeakPolarHBondContact O-CD 3.45Å; N63-F67 WeakPolarHBondContact O-CB 3.32Å; N63-F67 PolarHBondContact O-N 2.9Å
64	I	85.3	Confident	85	Confident	74 Å²	74	67.4 Å²	67.4	38%	0.379	39%	0.394	S	S	.	.	H	α-helix	trans	-66.5	-40	-172.4	-160.6	155.3	0	0	0	112.8	V60 F67 G68	V60-I64 HydrophobicContact CG1-CB 4.19Å; V60-I64 HydrophobicContact CG1-CD1 3.94Å; V60-I64 HydrophobicContact CG1-CG2 4.35Å; V60-I64 WeakPolarHBondContact O-CB 3.27Å; V60-I64 WeakPolarHBondContact O-CG2 3.43Å; V60-I64 PolarHBondContact O-N 3.46Å; I64-F67 PolarHBondContact O-N 3.35Å; I64-G68 PolarHBondContact O-N 3.15Å
65	T	82.9	Confident	84.9	Confident	38 Å²	38	72.3 Å²	72.3	23%	0.233	40%	0.403	C	S	.	.	H	α-helix	trans	-69.8	-49.5	-177.7	-51.5	0	0	0	0	111.7	N63 F67 G68 A69 F84 F87	N63-T65 PolarHBondContact O-N 2.9Å; T65-F67 PolarHBondContact O-N 3.03Å; T65-G68 PolarHBondContact O-N 2.85Å; T65-A69 WeakPolarHBondContact O-CB 3.34Å; T65-A69 PolarHBondContact O-N 3.14Å; T65-A69 VanDerWaalsContact O-N 3.07Å; T65-F84 HydrophobicContact CG2-CD1 4.37Å; T65-F84 HydrophobicContact CG2-CE1 3.56Å; T65-F84 HydrophobicContact CG2-CZ 4.44Å; T65-F87 HydrophobicContact CG2-CE1 4.06Å; T65-F87 WeakPolarHBondContact OG1-CZ 3.36Å
66	P	78.6	Confident	84.7	Confident	56 Å²	56	68.2 Å²	68.2	36%	0.364	39%	0.388	S	S	.	.	H	α-helix	trans	-60	-42.3	171.3	-23.9	34.4	0	0	0	113.1	N63 G68 A69 D70	N63-P66 WeakPolarHBondContact O-CD 3.45Å; P66-G68 PolarHBondContact O-N 3.44Å; P66-A69 PolarHBondContact O-N 3.33Å; P66-D70 WeakPolarHBondContact O-CB 3.26Å; P66-D70 PolarHBondContact O-N 2.85Å
67	F	85.5	Confident	84.5	Confident	62 Å²	62	72.2 Å²	72.2	27%	0.272	41%	0.407	S	S	.	.	H	α-helix	trans	-60.7	-45.3	-180	178.8	-100.6	0	0	0	112.2	N63 I64 T65 D70 Q71 F129 F136	N63-F67 WeakPolarHBondContact O-CB 3.32Å; N63-F67 PolarHBondContact O-N 2.9Å; I64-F67 PolarHBondContact O-N 3.35Å; T65-F67 PolarHBondContact O-N 3.03Å; F67-D70 PolarHBondContact O-N 2.99Å; F67-Q71 WeakPolarHBondContact O-CG 3.49Å; F67-Q71 PolarHBondContact O-N 3.38Å; F67-Q71 PolarHBondContact O-NE2 3.32Å; F67-Q71 VanDerWaalsContact O-NE2 3.12Å; F67-F129 HydrophobicContact CD1-CE2 4.09Å; F67-F129 AromaticContact CE1-CE2 3.63Å; F67-F129 HydrophobicContact CE1-CE2 3.63Å; F67-F129 HydrophobicContact CE1-CZ 4.02Å; F67-F129 HydrophobicContact CZ-CE2 4.31Å; F67-F129 HydrophobicContact CZ-CZ 4.27Å; F67-F136 HydrophobicContact CE1-CD1 4.01Å; F67-F136 AromaticContact CE1-CD2 3.99Å; F67-F136 HydrophobicContact CE1-CD2 3.99Å; F67-F136 HydrophobicContact CE1-CE1 4.19Å; F67-F136 HydrophobicContact CE1-CE2 4.15Å; F67-F136 AromaticContact CE1-CG 3.94Å; F67-F136 HydrophobicContact CE1-CG 3.94Å; F67-F136 HydrophobicContact CE1-CZ 4.26Å; F67-F136 HydrophobicContact CZ-CB 3.73Å; F67-F136 HydrophobicContact CZ-CD1 4.07Å; F67-F136 AromaticContact CZ-CD2 3.69Å; F67-F136 HydrophobicContact CZ-CD2 3.69Å; F67-F136 HydrophobicContact CZ-CE2 4.29Å; F67-F136 AromaticContact CZ-CG 3.58Å; F67-F136 HydrophobicContact CZ-CG 3.58Å
68	G	88.1	Confident	84.4	Confident	12 Å²	12	74 Å²	74	12%	0.124	41%	0.41	C	S	.	.	H	α-helix	trans	-66.8	-40.5	177.3	0	0	0	0	0	112.9	I64 T65 P66 D70 Q71 F83	I64-G68 PolarHBondContact O-N 3.15Å; T65-G68 PolarHBondContact O-N 2.85Å; P66-G68 PolarHBondContact O-N 3.44Å; G68-D70 VanDerWaalsContact C-N 3.27Å; G68-D70 PolarHBondContact O-N 3.48Å; G68-Q71 WeakPolarHBondContact O-CB 2.95Å; G68-Q71 PolarHBondContact O-N 3.4Å; G68-Q71 VanDerWaalsContact O-N 3.17Å; G68-F83 VanDerWaalsContact C-CZ 3.49Å
69	A	84.6	Confident	84.6	Confident	13 Å²	13	73.2 Å²	73.2	11%	0.107	40%	0.4	C	S	.	.	H	α-helix	trans	-61.4	-37.6	175.5	0	0	0	0	0	111.9	T65 P66 Q71 V72 K73 F83 F84	T65-A69 WeakPolarHBondContact O-CB 3.34Å; T65-A69 PolarHBondContact O-N 3.14Å; T65-A69 VanDerWaalsContact O-N 3.07Å; P66-A69 PolarHBondContact O-N 3.33Å; A69-Q71 PolarHBondContact O-N 2.9Å; A69-V72 WeakPolarHBondContact O-CG2 3.01Å; A69-V72 PolarHBondContact O-N 3.24Å; A69-K73 PolarHBondContact O-N 3.34Å; A69-F83 HydrophobicContact CB-CE1 4.33Å; A69-F84 HydrophobicContact CB-CE2 3.93Å; A69-F84 HydrophobicContact CB-CZ 3.65Å
70	D	85.7	Confident	84.6	Confident	44 Å²	44	70.7 Å²	70.7	24%	0.235	38%	0.384	C	S	.	.	H	α-helix	trans	-64.4	-26.1	177.6	-83.8	-13.8	0	0	0	113.7	P66 F67 G68 V72 K139	P66-D70 WeakPolarHBondContact O-CB 3.26Å; P66-D70 PolarHBondContact O-N 2.85Å; F67-D70 PolarHBondContact O-N 2.99Å; G68-D70 VanDerWaalsContact C-N 3.27Å; G68-D70 PolarHBondContact O-N 3.48Å; D70-V72 VanDerWaalsContact C-N 3.27Å; D70-V72 PolarHBondContact O-N 3.4Å; D70-K139 IonicContact OD1-NZ 2.68Å; D70-K139 PolarHBondContact OD1-NZ 2.91Å; D70-K139 WeakPolarHBondContact OD2-CD 3.31Å; D70-K139 WeakPolarHBondContact OD2-CE 3.49Å; D70-K139 IonicContact OD2-NZ 2.92Å; D70-K139 PolarHBondContact OD2-NZ 3.5Å
71	Q	90.6	Very high	84.5	Confident	40 Å²	40	75.5 Å²	75.5	19%	0.187	39%	0.394	C	S	.	.	H	α-helix	trans	-71	-22.4	177.6	-53.2	-48.7	-60.8	0	0	113.3	F67 G68 A69 F136 I137	F67-Q71 WeakPolarHBondContact O-CG 3.49Å; F67-Q71 PolarHBondContact O-N 3.38Å; F67-Q71 PolarHBondContact O-NE2 3.32Å; F67-Q71 VanDerWaalsContact O-NE2 3.12Å; G68-Q71 WeakPolarHBondContact O-CB 2.95Å; G68-Q71 PolarHBondContact O-N 3.4Å; G68-Q71 VanDerWaalsContact O-N 3.17Å; A69-Q71 PolarHBondContact O-N 2.9Å; Q71-F136 HydrophobicContact CG-CD1 4.44Å; Q71-I137 PolarHBondContact NE2-O 3.34Å; Q71-I137 VanDerWaalsContact NE2-O 3.15Å
72	V	90.4	Very high	84.9	Confident	29 Å²	29	76.7 Å²	76.7	18%	0.176	40%	0.395	C	S	.	.	H	α-helix	trans	-115.6	-2.7	-176.8	-63.1	0	0	0	0	113.1	A69 D70 D74 K75 F83	A69-V72 WeakPolarHBondContact O-CG2 3.01Å; A69-V72 PolarHBondContact O-N 3.24Å; D70-V72 VanDerWaalsContact C-N 3.27Å; D70-V72 PolarHBondContact O-N 3.4Å; V72-D74 VanDerWaalsContact C-N 3.3Å; V72-D74 PolarHBondContact O-N 3.33Å; V72-K75 WeakPolarHBondContact O-CB 3.14Å; V72-K75 PolarHBondContact O-N 3.43Å; V72-K75 VanDerWaalsContact O-N 3.09Å; V72-F83 HydrophobicContact CG2-CB 3.82Å; V72-F83 HydrophobicContact CG2-CD1 4.49Å; V72-F83 HydrophobicContact CG2-CG 4.09Å
73	K	83.1	Confident	85.5	Confident	120 Å²	120	76 Å²	76	52%	0.522	38%	0.384	S	S	.	.	G	3₁₀ helix	trans	-58.1	-41.6	-174.2	-170.2	176.8	-176.3	177.6	0	112.5	A69 K75 G76	A69-K73 PolarHBondContact O-N 3.34Å; K73-K75 PolarHBondContact O-N 3.15Å; K73-G76 PolarHBondContact O-N 3.2Å
74	D	87.4	Confident	85.8	Confident	136 Å²	136	75.2 Å²	75.2	73%	0.727	38%	0.376	S	S	*	.	G	3₁₀ helix	trans	-73.3	-15.1	-177.4	-58.2	-28.1	0	0	0	112.9	V72 G76	V72-D74 VanDerWaalsContact C-N 3.3Å; V72-D74 PolarHBondContact O-N 3.33Å; D74-G76 PolarHBondContact O-N 3.27Å
75	K	87.8	Confident	85.7	Confident	167 Å²	167	75.7 Å²	75.7	73%	0.726	38%	0.379	S	S	*	.	G	3₁₀ helix	trans	-82.2	4.2	174.3	-58.9	-173.2	179.9	-176.3	0	113	V72 K73 A79	V72-K75 WeakPolarHBondContact O-CB 3.14Å; V72-K75 PolarHBondContact O-N 3.43Å; V72-K75 VanDerWaalsContact O-N 3.09Å; K73-K75 PolarHBondContact O-N 3.15Å; K75-A79 HydrophobicContact CB-CB 3.57Å
76	G	87.6	Confident	85.9	Confident	24 Å²	24	82.6 Å²	82.6	25%	0.247	40%	0.401	C	S	.	.			trans	93	175	176.4	0	0	0	0	0	114.8	K73 D74 E78 A79 T80	K73-G76 PolarHBondContact O-N 3.2Å; D74-G76 PolarHBondContact O-N 3.27Å; G76-E78 VanDerWaalsContact C-N 3.29Å; G76-E78 PolarHBondContact O-N 3.37Å; G76-A79 PolarHBondContact O-N 2.9Å; G76-T80 PolarHBondContact O-N 3.49Å; G76-T80 PolarHBondContact O-OG1 2.89Å
77	P	84.9	Confident	86.3	Confident	117 Å²	117	83 Å²	83	76%	0.76	40%	0.397	S	S	*	.	H	α-helix	trans	-66.7	-29.4	-172.3	25.8	-34.2	0	0	0	113	R81	P77-R81 WeakPolarHBondContact O-CB 3.37Å; P77-R81 PolarHBondContact O-N 2.92Å
78	E	85.7	Confident	86.2	Confident	120 Å²	120	84.5 Å²	84.5	56%	0.561	40%	0.402	S	S	*	.	H	α-helix	trans	-70.4	-43.6	179.9	-165.4	-179.1	168.2	0	0	112.1	G76 T80 R81 R82	G76-E78 VanDerWaalsContact C-N 3.29Å; G76-E78 PolarHBondContact O-N 3.37Å; E78-T80 VanDerWaalsContact C-N 3.33Å; E78-T80 PolarHBondContact O-N 3.14Å; E78-R81 PolarHBondContact O-N 3.32Å; E78-R82 WeakPolarHBondContact O-CG 3.43Å; E78-R82 PolarHBondContact O-N 3.39Å; E78-R82 IonicContact OE1-CZ 2.78Å; E78-R82 IonicContact OE1-NE 2.61Å; E78-R82 PolarHBondContact OE1-NE 3.07Å; E78-R82 IonicContact OE1-NH2 2.72Å; E78-R82 PolarHBondContact OE1-NH2 3.46Å
79	A	87.4	Confident	85.9	Confident	27 Å²	27	92.1 Å²	92.1	22%	0.223	43%	0.427	C	S	.	.	H	α-helix	trans	-61.6	-43.2	175.3	0	0	0	0	0	111.4	K75 G76 R81 R82 F83	K75-A79 HydrophobicContact CB-CB 3.57Å; G76-A79 PolarHBondContact O-N 2.9Å; A79-R81 PolarHBondContact O-N 3.38Å; A79-R82 PolarHBondContact O-N 2.96Å; A79-F83 PolarHBondContact O-N 3.49Å
80	T	83.4	Confident	86.1	Confident	30 Å²	30	95.1 Å²	95.1	18%	0.184	45%	0.446	C	S	.	.	H	α-helix	trans	-59.2	-45.8	174.9	-57.2	0	0	0	0	111.4	G76 E78 R82 F83 F84	G76-T80 PolarHBondContact O-N 3.49Å; G76-T80 PolarHBondContact O-OG1 2.89Å; E78-T80 VanDerWaalsContact C-N 3.33Å; E78-T80 PolarHBondContact O-N 3.14Å; T80-R82 PolarHBondContact O-N 3.38Å; T80-F83 WeakPolarHBondContact O-CB 3.35Å; T80-F83 PolarHBondContact O-N 2.92Å; T80-F84 HydrophobicContact CG2-CD2 3.83Å; T80-F84 HydrophobicContact CG2-CE2 3.58Å; T80-F84 WeakPolarHBondContact O-CD2 3.41Å; T80-F84 PolarHBondContact O-N 2.91Å
81	R	82.2	Confident	86.1	Confident	180 Å²	180	97.3 Å²	97.3	68%	0.679	46%	0.457	S	S	*	.	H	α-helix	trans	-62.8	-42.4	176.7	-173.5	179.8	-179.1	-174.2	0.5	112.4	P77 E78 A79 F83 F84 N85	P77-R81 WeakPolarHBondContact O-CB 3.37Å; P77-R81 PolarHBondContact O-N 2.92Å; E78-R81 PolarHBondContact O-N 3.32Å; A79-R81 PolarHBondContact O-N 3.38Å; R81-F83 VanDerWaalsContact C-N 3.34Å; R81-F84 PolarHBondContact O-N 2.88Å; R81-N85 VanDerWaalsContact O-CG 3.25Å; R81-N85 PolarHBondContact O-N 2.97Å
82	R	86.8	Confident	85.5	Confident	151 Å²	151	96.2 Å²	96.2	57%	0.57	45%	0.452	S	S	*	.	H	α-helix	trans	-62	-41.3	176.5	-72.1	179	-172.2	-170.9	3.3	111.6	E78 A79 T80 N85 W86	E78-R82 WeakPolarHBondContact O-CG 3.43Å; E78-R82 PolarHBondContact O-N 3.39Å; E78-R82 IonicContact OE1-CZ 2.78Å; E78-R82 IonicContact OE1-NE 2.61Å; E78-R82 PolarHBondContact OE1-NE 3.07Å; E78-R82 IonicContact OE1-NH2 2.72Å; E78-R82 PolarHBondContact OE1-NH2 3.46Å; A79-R82 PolarHBondContact O-N 2.96Å; T80-R82 PolarHBondContact O-N 3.38Å; R82-N85 PolarHBondContact O-N 2.98Å; R82-W86 PolarHBondContact O-N 3.32Å
83	F	88.8	Confident	85.2	Confident	55 Å²	55	100.1 Å²	100.1	24%	0.241	47%	0.472	C	S	.	.	H	α-helix	trans	-57.9	-51.6	173.6	168	-95.8	0	0	0	111.5	G68 A69 V72 A79 T80 R81 N85 W86 F87	G68-F83 VanDerWaalsContact C-CZ 3.49Å; A69-F83 HydrophobicContact CB-CE1 4.33Å; V72-F83 HydrophobicContact CG2-CB 3.82Å; V72-F83 HydrophobicContact CG2-CD1 4.49Å; V72-F83 HydrophobicContact CG2-CG 4.09Å; A79-F83 PolarHBondContact O-N 3.49Å; T80-F83 WeakPolarHBondContact O-CB 3.35Å; T80-F83 PolarHBondContact O-N 2.92Å; R81-F83 VanDerWaalsContact C-N 3.34Å; F83-N85 VanDerWaalsContact C-N 3.32Å; F83-N85 PolarHBondContact O-N 3.06Å; F83-W86 PolarHBondContact O-N 3.44Å; F83-F87 VanDerWaalsContact O-CB 3.31Å; F83-F87 WeakPolarHBondContact O-CB 3.4Å; F83-F87 PolarHBondContact O-N 3.48Å
84	F	84.7	Confident	85.5	Confident	84 Å²	84	96.2 Å²	96.2	37%	0.368	47%	0.465	S	S	.	.	H	α-helix	trans	-62.2	-37.9	178.9	-80	-66.9	0	0	0	112.9	T65 A69 T80 R81 F87 Y88	T65-F84 HydrophobicContact CG2-CD1 4.37Å; T65-F84 HydrophobicContact CG2-CE1 3.56Å; T65-F84 HydrophobicContact CG2-CZ 4.44Å; A69-F84 HydrophobicContact CB-CE2 3.93Å; A69-F84 HydrophobicContact CB-CZ 3.65Å; T80-F84 HydrophobicContact CG2-CD2 3.83Å; T80-F84 HydrophobicContact CG2-CE2 3.58Å; T80-F84 WeakPolarHBondContact O-CD2 3.41Å; T80-F84 PolarHBondContact O-N 2.91Å; R81-F84 PolarHBondContact O-N 2.88Å; F84-F87 PolarHBondContact O-N 2.92Å; F84-Y88 VanDerWaalsContact O-CB 3.32Å; F84-Y88 WeakPolarHBondContact O-CB 3.45Å; F84-Y88 PolarHBondContact O-N 3.45Å
85	N	83.4	Confident	85.3	Confident	85 Å²	85	91.2 Å²	91.2	46%	0.455	44%	0.443	S	S	.	.	H	α-helix	trans	-63	-47.1	175.5	-72.1	-12.1	0	0	0	111.8	R81 R82 F83 Y88 W89	R81-N85 VanDerWaalsContact O-CG 3.25Å; R81-N85 PolarHBondContact O-N 2.97Å; R82-N85 PolarHBondContact O-N 2.98Å; F83-N85 VanDerWaalsContact C-N 3.32Å; F83-N85 PolarHBondContact O-N 3.06Å; N85-Y88 PolarHBondContact O-N 3.5Å; N85-W89 VanDerWaalsContact O-CD1 3.26Å; N85-W89 PolarHBondContact O-N 3.3Å
86	W	87.9	Confident	85	Confident	183 Å²	183	86.5 Å²	86.5	69%	0.693	43%	0.425	S	S	*	.	H	α-helix	trans	-64.3	-43.9	176.8	-91	110.2	0	0	0	112.1	R82 F83 Y88 W89 C90	R82-W86 PolarHBondContact O-N 3.32Å; F83-W86 PolarHBondContact O-N 3.44Å; W86-Y88 VanDerWaalsContact C-N 3.29Å; W86-Y88 PolarHBondContact O-N 3.49Å; W86-W89 PolarHBondContact O-N 2.81Å; W86-C90 PolarHBondContact O-N 3.38Å; W86-C90 PolarHBondContact O-SG 3.25Å
87	F	87.4	Confident	85	Confident	63 Å²	63	89.6 Å²	89.6	28%	0.276	44%	0.438	S	S	.	.	H	α-helix	trans	-56.2	-45.2	175.3	-178.4	-106.4	0	0	0	111.5	T65 F83 F84 C90 I91	T65-F87 HydrophobicContact CG2-CE1 4.06Å; T65-F87 WeakPolarHBondContact OG1-CZ 3.36Å; F83-F87 VanDerWaalsContact O-CB 3.31Å; F83-F87 WeakPolarHBondContact O-CB 3.4Å; F83-F87 PolarHBondContact O-N 3.48Å; F84-F87 PolarHBondContact O-N 2.92Å; F87-C90 PolarHBondContact O-N 2.9Å; F87-I91 HydrophobicContact CD1-CD1 3.72Å; F87-I91 HydrophobicContact CE1-CD1 3.28Å; F87-I91 HydrophobicContact CE1-CG1 4.4Å; F87-I91 HydrophobicContact CE2-CD1 4.28Å; F87-I91 HydrophobicContact CG-CD1 4.39Å; F87-I91 HydrophobicContact CZ-CD1 3.61Å; F87-I91 HydrophobicContact CZ-CG1 4.42Å; F87-I91 WeakPolarHBondContact O-CG1 3.38Å; F87-I91 PolarHBondContact O-N 3.44Å
88	Y	81.9	Confident	85.1	Confident	95 Å²	95	86.7 Å²	86.7	37%	0.373	42%	0.421	S	S	.	.	H	α-helix	trans	-62.2	-45	176.1	-175.7	-96.1	0	0	0	112.4	F84 N85 W86 C90 I91 N92 I264	F84-Y88 VanDerWaalsContact O-CB 3.32Å; F84-Y88 WeakPolarHBondContact O-CB 3.45Å; F84-Y88 PolarHBondContact O-N 3.45Å; N85-Y88 PolarHBondContact O-N 3.5Å; W86-Y88 VanDerWaalsContact C-N 3.29Å; W86-Y88 PolarHBondContact O-N 3.49Å; Y88-C90 PolarHBondContact O-N 3.4Å; Y88-I91 PolarHBondContact O-N 2.96Å; Y88-N92 WeakPolarHBondContact CD1-ND2 3.41Å; Y88-N92 WeakPolarHBondContact CE1-ND2 3.36Å; Y88-N92 PolarHBondContact O-N 3.06Å; Y88-N92 VanDerWaalsContact O-N 3.17Å; Y88-N92 PolarHBondContact O-ND2 3.47Å; Y88-I264 WeakPolarHBondContact OH-CD1 3.35Å
89	W	81.9	Confident	84.9	Confident	172 Å²	172	83.1 Å²	83.1	65%	0.652	41%	0.406	S	S	*	.	H	α-helix	trans	-60	-44	175	-87.1	110.8	0	0	0	112.6	N85 W86 I91 N92 L93	N85-W89 VanDerWaalsContact O-CD1 3.26Å; N85-W89 PolarHBondContact O-N 3.3Å; W86-W89 PolarHBondContact O-N 2.81Å; W89-I91 PolarHBondContact O-N 3.13Å; W89-N92 PolarHBondContact O-N 3.24Å; W89-L93 WeakPolarHBondContact O-CB 3.5Å; W89-L93 PolarHBondContact O-N 3.03Å
90	C	89	Confident	84.7	Confident	76 Å²	76	82.5 Å²	82.5	51%	0.514	40%	0.402	S	S	.	.	H	α-helix	trans	-62.3	-41.7	178	-68.4	0	0	0	0	112.5	W86 F87 Y88 G94	W86-C90 PolarHBondContact O-N 3.38Å; W86-C90 PolarHBondContact O-SG 3.25Å; F87-C90 PolarHBondContact O-N 2.9Å; Y88-C90 PolarHBondContact O-N 3.4Å; C90-G94 PolarHBondContact O-N 3.07Å
91	I	85.1	Confident	84.9	Confident	89 Å²	89	82.8 Å²	82.8	46%	0.456	41%	0.411	S	S	.	.	H	α-helix	trans	-60.2	-49	176.7	-73.5	169.9	0	0	0	110.7	F87 Y88 W89 G94 A95	F87-I91 HydrophobicContact CD1-CD1 3.72Å; F87-I91 HydrophobicContact CE1-CD1 3.28Å; F87-I91 HydrophobicContact CE1-CG1 4.4Å; F87-I91 HydrophobicContact CE2-CD1 4.28Å; F87-I91 HydrophobicContact CG-CD1 4.39Å; F87-I91 HydrophobicContact CZ-CD1 3.61Å; F87-I91 HydrophobicContact CZ-CG1 4.42Å; F87-I91 WeakPolarHBondContact O-CG1 3.38Å; F87-I91 PolarHBondContact O-N 3.44Å; Y88-I91 PolarHBondContact O-N 2.96Å; W89-I91 PolarHBondContact O-N 3.13Å; I91-G94 PolarHBondContact O-N 3.36Å; I91-A95 WeakPolarHBondContact O-CB 3.31Å; I91-A95 PolarHBondContact O-N 2.97Å
92	N	79.8	Confident	85.1	Confident	18 Å²	18	75.1 Å²	75.1	10%	0.096	38%	0.384	C	S	.	.	H	α-helix	trans	-67.8	-43.7	-176.2	-77.7	-72	0	0	0	112.4	Y88 W89 G94 A95 I96 L261	Y88-N92 WeakPolarHBondContact CD1-ND2 3.41Å; Y88-N92 WeakPolarHBondContact CE1-ND2 3.36Å; Y88-N92 PolarHBondContact O-N 3.06Å; Y88-N92 VanDerWaalsContact O-N 3.17Å; Y88-N92 PolarHBondContact O-ND2 3.47Å; W89-N92 PolarHBondContact O-N 3.24Å; N92-G94 VanDerWaalsContact C-N 3.34Å; N92-G94 PolarHBondContact O-N 3.31Å; N92-A95 PolarHBondContact O-N 3.2Å; N92-I96 WeakPolarHBondContact O-CG1 3.37Å; N92-I96 PolarHBondContact O-N 2.56Å; N92-L261 HydrophobicContact CB-CD1 4Å; N92-L261 HydrophobicContact CB-CD2 3.73Å; N92-L261 HydrophobicContact CB-CG 4.28Å; N92-L261 WeakPolarHBondContact OD1-CD2 3.32Å; N92-L261 WeakPolarHBondContact OD1-CG 3.44Å
93	L	84.1	Confident	84.9	Confident	111 Å²	111	68 Å²	68	58%	0.581	36%	0.358	S	S	*	.	H	α-helix	trans	-61.3	-44.7	173.8	-177.1	64.2	0	0	0	111.1	W89 A95 I96 V97	W89-L93 WeakPolarHBondContact O-CB 3.5Å; W89-L93 PolarHBondContact O-N 3.03Å; L93-A95 VanDerWaalsContact C-N 3.31Å; L93-A95 PolarHBondContact O-N 3.46Å; L93-I96 PolarHBondContact O-N 2.88Å; L93-V97 WeakPolarHBondContact O-CG2 3.32Å; L93-V97 PolarHBondContact O-N 2.84Å
94	G	88.3	Confident	84.7	Confident	37 Å²	37	68.6 Å²	68.6	38%	0.381	36%	0.359	S	S	.	.	H	α-helix	trans	-59.5	-40.1	175.8	0	0	0	0	0	112.8	C90 I91 N92 V97 S98	C90-G94 PolarHBondContact O-N 3.07Å; I91-G94 PolarHBondContact O-N 3.36Å; N92-G94 VanDerWaalsContact C-N 3.34Å; N92-G94 PolarHBondContact O-N 3.31Å; G94-V97 PolarHBondContact O-N 3.3Å; G94-S98 WeakPolarHBondContact O-CB 3.34Å; G94-S98 PolarHBondContact O-N 2.92Å
95	A	83.7	Confident	84.7	Confident	31 Å²	31	66.8 Å²	66.8	26%	0.256	35%	0.353	S	S	.	.	H	α-helix	trans	-64.1	-43.8	176.3	0	0	0	0	0	112	I91 N92 L93 S98 L99	I91-A95 WeakPolarHBondContact O-CB 3.31Å; I91-A95 PolarHBondContact O-N 2.97Å; N92-A95 PolarHBondContact O-N 3.2Å; L93-A95 VanDerWaalsContact C-N 3.31Å; L93-A95 PolarHBondContact O-N 3.46Å; A95-S98 PolarHBondContact O-N 3.25Å; A95-L99 VanDerWaalsContact O-CB 3.29Å; A95-L99 WeakPolarHBondContact O-CB 3.49Å; A95-L99 VanDerWaalsContact O-CG 3.3Å; A95-L99 WeakPolarHBondContact O-CG 3.19Å; A95-L99 PolarHBondContact O-N 2.91Å
96	I	81.9	Confident	84.6	Confident	68 Å²	68	64.6 Å²	64.6	35%	0.349	34%	0.34	S	S	.	.	H	α-helix	trans	-62.6	-47.3	176.4	-66.1	167.1	0	0	0	110.7	N92 L93 S98 G100 L261	N92-I96 WeakPolarHBondContact O-CG1 3.37Å; N92-I96 PolarHBondContact O-N 2.56Å; L93-I96 PolarHBondContact O-N 2.88Å; I96-S98 VanDerWaalsContact C-N 3.35Å; I96-S98 PolarHBondContact O-N 2.89Å; I96-G100 WeakPolarHBondContact O-CA 3.36Å; I96-G100 PolarHBondContact O-N 3.21Å; I96-L261 HydrophobicContact CD1-CD1 3.88Å
97	V	87.1	Confident	83.9	Confident	89 Å²	89	58.2 Å²	58.2	54%	0.539	32%	0.318	S	S	.	.	I	π-helix	trans	-64.1	-41	179	173.8	0	0	0	0	111.3	L93 G94 G101 V102	L93-V97 WeakPolarHBondContact O-CG2 3.32Å; L93-V97 PolarHBondContact O-N 2.84Å; G94-V97 PolarHBondContact O-N 3.3Å; V97-G101 VanDerWaalsContact O-CA 3.31Å; V97-G101 WeakPolarHBondContact O-CA 3.39Å; V97-G101 PolarHBondContact O-N 3.13Å; V97-V102 PolarHBondContact O-N 3.21Å
98	S	87.4	Confident	83.3	Confident	56 Å²	56	57.9 Å²	57.9	39%	0.392	32%	0.319	S	S	.	.	I	π-helix	trans	-69.5	-53.7	179.7	-172.8	0	0	0	0	111.8	G94 A95 I96 V102 G103	G94-S98 WeakPolarHBondContact O-CB 3.34Å; G94-S98 PolarHBondContact O-N 2.92Å; A95-S98 PolarHBondContact O-N 3.25Å; I96-S98 VanDerWaalsContact C-N 3.35Å; I96-S98 PolarHBondContact O-N 2.89Å; S98-V102 WeakPolarHBondContact O-CA 3.42Å; S98-V102 VanDerWaalsContact O-CB 3.27Å; S98-V102 WeakPolarHBondContact O-CB 3.36Å; S98-V102 PolarHBondContact O-N 2.97Å; S98-V102 VanDerWaalsContact O-N 3.13Å; S98-G103 PolarHBondContact O-N 3.27Å
99	L	81.3	Confident	83.1	Confident	46 Å²	46	61.6 Å²	61.6	24%	0.241	33%	0.333	C	S	.	.	I	π-helix	trans	-70.5	-38.4	-176.8	-64.1	173.2	0	0	0	111.8	A95 W251 M254 A257	A95-L99 VanDerWaalsContact O-CB 3.29Å; A95-L99 WeakPolarHBondContact O-CB 3.49Å; A95-L99 VanDerWaalsContact O-CG 3.3Å; A95-L99 WeakPolarHBondContact O-CG 3.19Å; A95-L99 PolarHBondContact O-N 2.91Å; L99-W251 PolarHBondContact O-NE1 2.97Å; L99-M254 HydrophobicContact CB-CB 3.89Å; L99-M254 HydrophobicContact CB-CG 4.14Å; L99-M254 HydrophobicContact CD1-CB 4.2Å; L99-A257 HydrophobicContact CD1-CB 4.36Å
100	G	83.4	Confident	82.9	Confident	14 Å²	14	55.4 Å²	55.4	14%	0.144	32%	0.317	C	S	.	.	I	π-helix	trans	-72.4	-62.8	176.8	0	0	0	0	0	112.2	I96 Y104 W251	I96-G100 WeakPolarHBondContact O-CA 3.36Å; I96-G100 PolarHBondContact O-N 3.21Å; G100-Y104 WeakPolarHBondContact O-CB 3.21Å; G100-Y104 PolarHBondContact O-N 3Å; G100-W251 PolarHBondContact O-NE1 3.39Å
101	G	86.3	Confident	82.6	Confident	36 Å²	36	57.1 Å²	57.1	37%	0.371	32%	0.315	S	S	.	.	I	π-helix	trans	-79.4	-58.1	-172	0	0	0	0	0	113.9	V97 G103 Y104 I105	V97-G101 VanDerWaalsContact O-CA 3.31Å; V97-G101 WeakPolarHBondContact O-CA 3.39Å; V97-G101 PolarHBondContact O-N 3.13Å; G101-G103 VanDerWaalsContact C-N 3.34Å; G101-G103 PolarHBondContact O-N 3.26Å; G101-Y104 WeakPolarHBondContact O-CB 3.27Å; G101-Y104 PolarHBondContact O-N 3.41Å; G101-I105 WeakPolarHBondContact O-CG1 3.13Å; G101-I105 PolarHBondContact O-N 2.81Å
102	V	87.1	Confident	82.5	Confident	18 Å²	18	59.5 Å²	59.5	11%	0.109	33%	0.325	C	S	.	.	I	π-helix	trans	-65	-40.8	-178.3	-178.5	0	0	0	0	110.7	V97 S98 Y104 I105 Q106 G114 I117 P118	V97-V102 PolarHBondContact O-N 3.21Å; S98-V102 WeakPolarHBondContact O-CA 3.42Å; S98-V102 VanDerWaalsContact O-CB 3.27Å; S98-V102 WeakPolarHBondContact O-CB 3.36Å; S98-V102 PolarHBondContact O-N 2.97Å; S98-V102 VanDerWaalsContact O-N 3.13Å; V102-Y104 VanDerWaalsContact C-N 3.3Å; V102-Y104 PolarHBondContact O-N 2.67Å; V102-I105 PolarHBondContact O-N 3.32Å; V102-Q106 HydrophobicContact CG1-CG 4.32Å; V102-Q106 VanDerWaalsContact O-CG 3.3Å; V102-Q106 WeakPolarHBondContact O-CG 3.17Å; V102-Q106 PolarHBondContact O-N 2.61Å; V102-G114 VanDerWaalsContact CG1-O 3.24Å; V102-G114 WeakPolarHBondContact CG1-O 3.43Å; V102-I117 HydrophobicContact CG2-CG2 4Å; V102-P118 HydrophobicContact CG1-CG 4.17Å
103	G	83.1	Confident	82.8	Confident	3 Å²	3	62.1 Å²	62.1	3%	0.031	34%	0.341	C	S	.	.	H	α-helix	trans	-59.2	-38.2	174.2	0	0	0	0	0	113.4	S98 G101 Q107	S98-G103 PolarHBondContact O-N 3.27Å; G101-G103 VanDerWaalsContact C-N 3.34Å; G101-G103 PolarHBondContact O-N 3.26Å; G103-Q107 WeakPolarHBondContact O-CG 3.27Å; G103-Q107 PolarHBondContact O-N 2.93Å
104	Y	83.3	Confident	82.9	Confident	66 Å²	66	56.8 Å²	56.8	26%	0.259	31%	0.313	S	S	.	.	H	α-helix	trans	-66.2	-44	174	179.4	-92.8	0	0	0	111.9	G100 G101 V102 Q106 Q107 N108 Y109 F245 P248 W251	G100-Y104 WeakPolarHBondContact O-CB 3.21Å; G100-Y104 PolarHBondContact O-N 3Å; G101-Y104 WeakPolarHBondContact O-CB 3.27Å; G101-Y104 PolarHBondContact O-N 3.41Å; V102-Y104 VanDerWaalsContact C-N 3.3Å; V102-Y104 PolarHBondContact O-N 2.67Å; Y104-Q106 VanDerWaalsContact C-N 3.34Å; Y104-Q106 PolarHBondContact O-N 2.78Å; Y104-Q107 PolarHBondContact O-N 2.72Å; Y104-N108 WeakPolarHBondContact CD2-ND2 3.28Å; Y104-N108 HydrophobicContact CE1-CB 4.43Å; Y104-N108 WeakPolarHBondContact CE2-ND2 3.35Å; Y104-N108 WeakPolarHBondContact O-CB 3.48Å; Y104-N108 PolarHBondContact O-N 2.9Å; Y104-N108 PolarHBondContact O-ND2 3.49Å; Y104-Y109 HydrophobicContact CD1-CE2 4.41Å; Y104-Y109 AromaticContact CE1-CE2 3.84Å; Y104-Y109 HydrophobicContact CE1-CE2 3.84Å; Y104-F245 HydrophobicContact CE2-CD2 4.35Å; Y104-F245 HydrophobicContact CE2-CE2 4.28Å; Y104-P248 HydrophobicContact CD2-CG 3.74Å; Y104-P248 HydrophobicContact CG-CG 4.42Å; Y104-W251 HydrophobicContact CD2-CZ2 4.11Å
105	I	85.3	Confident	82.9	Confident	47 Å²	47	62.1 Å²	62.1	24%	0.241	32%	0.323	C	S	.	.	H	α-helix	trans	-61.7	-43.2	176.9	-66.6	170.3	0	0	0	111	G101 V102 Q107 Y109 S110 V113 I117	G101-I105 WeakPolarHBondContact O-CG1 3.13Å; G101-I105 PolarHBondContact O-N 2.81Å; V102-I105 PolarHBondContact O-N 3.32Å; I105-Q107 VanDerWaalsContact C-N 3.33Å; I105-Q107 PolarHBondContact O-N 3.18Å; I105-Y109 WeakPolarHBondContact O-CA 3.37Å; I105-Y109 WeakPolarHBondContact O-CB 3.4Å; I105-Y109 PolarHBondContact O-N 2.7Å; I105-S110 PolarHBondContact O-N 3.47Å; I105-V113 HydrophobicContact CG2-CB 4.28Å; I105-V113 HydrophobicContact CG2-CG1 3.96Å; I105-I117 HydrophobicContact CD1-CD1 3.64Å; I105-I117 HydrophobicContact CG2-CD1 4.36Å
106	Q	82	Confident	83.3	Confident	39 Å²	39	64.9 Å²	64.9	18%	0.182	33%	0.332	C	S	.	.	H	α-helix	trans	-59	-43.3	179.4	-76.6	172.9	-20	0	0	112.4	V102 Y104 S110 F111	V102-Q106 HydrophobicContact CG1-CG 4.32Å; V102-Q106 VanDerWaalsContact O-CG 3.3Å; V102-Q106 WeakPolarHBondContact O-CG 3.17Å; V102-Q106 PolarHBondContact O-N 2.61Å; Y104-Q106 VanDerWaalsContact C-N 3.34Å; Y104-Q106 PolarHBondContact O-N 2.78Å; Q106-S110 CarbonylContact O-C 3.39Å; Q106-F111 HydrophobicContact CB-CD1 3.99Å; Q106-F111 HydrophobicContact CB-CE1 4.07Å; Q106-F111 HydrophobicContact CG-CD1 4.33Å; Q106-F111 WeakPolarHBondContact O-CD2 3.23Å; Q106-F111 WeakPolarHBondContact O-CE2 3.37Å; Q106-F111 PolarHBondContact O-N 3.38Å
107	Q	73.4	Confident	83.8	Confident	48 Å²	48	64.3 Å²	64.3	22%	0.224	33%	0.329	C	S	.	.	H	α-helix	trans	-88.4	-29.8	-173.1	-64.5	-167.8	1	0	0	113.9	G103 Y104 I105 P248	G103-Q107 WeakPolarHBondContact O-CG 3.27Å; G103-Q107 PolarHBondContact O-N 2.93Å; Y104-Q107 PolarHBondContact O-N 2.72Å; I105-Q107 VanDerWaalsContact C-N 3.33Å; I105-Q107 PolarHBondContact O-N 3.18Å; Q107-P248 HydrophobicContact CB-CB 4.39Å; Q107-P248 HydrophobicContact CG-CB 4.46Å; Q107-P248 VanDerWaalsContact OE1-C 3.24Å
108	N	74.7	Confident	84	Confident	57 Å²	57	62.7 Å²	62.7	31%	0.305	32%	0.32	S	S	.	.	H	α-helix	trans	-102.2	-29	-175.2	-64.4	-52.7	0	0	0	114.4	Y104 T246	Y104-N108 WeakPolarHBondContact CD2-ND2 3.28Å; Y104-N108 HydrophobicContact CE1-CB 4.43Å; Y104-N108 WeakPolarHBondContact CE2-ND2 3.35Å; Y104-N108 WeakPolarHBondContact O-CB 3.48Å; Y104-N108 PolarHBondContact O-N 2.9Å; Y104-N108 PolarHBondContact O-ND2 3.49Å; N108-T246 PolarHBondContact OD1-OG1 3.05Å
109	Y	76.7	Confident	84.3	Confident	172 Å²	172	62.9 Å²	62.9	68%	0.675	33%	0.325	S	S	*	.	T	Hydrogen-bonded Turn	trans	-107.4	-70.9	-179.4	-69.8	-96.4	0	0	0	111.4	Y104 I105	Y104-Y109 HydrophobicContact CD1-CE2 4.41Å; Y104-Y109 AromaticContact CE1-CE2 3.84Å; Y104-Y109 HydrophobicContact CE1-CE2 3.84Å; I105-Y109 WeakPolarHBondContact O-CA 3.37Å; I105-Y109 WeakPolarHBondContact O-CB 3.4Å; I105-Y109 PolarHBondContact O-N 2.7Å
110	S	78.1	Confident	84.9	Confident	43 Å²	43	64.4 Å²	64.4	30%	0.301	34%	0.337	S	S	.	.			trans	-168.2	138.8	-179.8	180	0	0	0	0	111	I105 Q106 E112 G114	I105-S110 PolarHBondContact O-N 3.47Å; Q106-S110 CarbonylContact O-C 3.39Å; S110-E112 VanDerWaalsContact C-N 3.26Å; S110-E112 PolarHBondContact O-N 3.32Å; S110-E112 PolarHBondContact OG-N 3.27Å; S110-G114 PolarHBondContact O-N 3.28Å; S110-G114 VanDerWaalsContact O-N 3.11Å
111	F	81.5	Confident	85.4	Confident	111 Å²	111	67.4 Å²	67.4	49%	0.487	35%	0.354	S	S	.	.	H	α-helix	trans	-62.4	-32.6	171.2	-76.2	-86.3	0	0	0	112.5	Q106 G114 Y115	Q106-F111 HydrophobicContact CB-CD1 3.99Å; Q106-F111 HydrophobicContact CB-CE1 4.07Å; Q106-F111 HydrophobicContact CG-CD1 4.33Å; Q106-F111 WeakPolarHBondContact O-CD2 3.23Å; Q106-F111 WeakPolarHBondContact O-CE2 3.37Å; Q106-F111 PolarHBondContact O-N 3.38Å; F111-G114 CarbonylContact O-C 3.59Å; F111-G114 PolarHBondContact O-N 2.93Å; F111-Y115 HydrophobicContact CB-CD2 4.39Å; F111-Y115 HydrophobicContact CB-CE2 4.09Å; F111-Y115 HydrophobicContact CD1-CE2 4.27Å; F111-Y115 WeakPolarHBondContact O-CD2 3.31Å; F111-Y115 PolarHBondContact O-N 2.86Å
112	E	84.3	Confident	85.7	Confident	140 Å²	140	72 Å²	72	65%	0.654	37%	0.37	S	S	*	.	H	α-helix	trans	-61.9	-53.2	179.7	-175.7	179.7	178.7	0	0	111.4	S110 G114 Y115 I116	S110-E112 VanDerWaalsContact C-N 3.26Å; S110-E112 PolarHBondContact O-N 3.32Å; S110-E112 PolarHBondContact OG-N 3.27Å; E112-G114 PolarHBondContact O-N 3.5Å; E112-Y115 PolarHBondContact O-N 2.96Å; E112-Y115 VanDerWaalsContact O-N 3.13Å; E112-I116 HydrophobicContact CG-CD1 4.14Å; E112-I116 WeakPolarHBondContact O-CG1 3.35Å; E112-I116 PolarHBondContact O-N 3.47Å
113	V	86	Confident	86.1	Confident	72 Å²	72	73 Å²	73	44%	0.436	38%	0.384	S	S	.	.	H	α-helix	trans	-59.4	-41.3	175.1	-179.7	0	0	0	0	110.3	I105 Y115 I116 I117	I105-V113 HydrophobicContact CG2-CB 4.28Å; I105-V113 HydrophobicContact CG2-CG1 3.96Å; V113-Y115 VanDerWaalsContact C-N 3.28Å; V113-Y115 PolarHBondContact O-N 3.01Å; V113-I116 PolarHBondContact O-N 3.38Å; V113-I117 HydrophobicContact CG1-CD1 4.3Å; V113-I117 WeakPolarHBondContact O-CG1 3.45Å; V113-I117 PolarHBondContact O-N 2.97Å
114	G	86.8	Confident	86.7	Confident	0 Å²	0	77.6 Å²	77.6	0%	0	41%	0.407	C	S	.	.	H	α-helix	trans	-62.4	-27.9	177.7	0	0	0	0	0	114.9	V102 S110 F111 E112 P118	V102-G114 VanDerWaalsContact CG1-O 3.24Å; V102-G114 WeakPolarHBondContact CG1-O 3.43Å; S110-G114 PolarHBondContact O-N 3.28Å; S110-G114 VanDerWaalsContact O-N 3.11Å; F111-G114 CarbonylContact O-C 3.59Å; F111-G114 PolarHBondContact O-N 2.93Å; E112-G114 PolarHBondContact O-N 3.5Å; G114-P118 WeakPolarHBondContact O-CD 3.46Å
115	Y	88.1	Confident	87.2	Confident	149 Å²	149	78 Å²	78	58%	0.584	42%	0.419	S	S	*	.	H	α-helix	trans	-88.7	-29.5	174.4	-71	-56.5	0	0	0	113.2	F111 E112 V113 I117 P118 A119	F111-Y115 HydrophobicContact CB-CD2 4.39Å; F111-Y115 HydrophobicContact CB-CE2 4.09Å; F111-Y115 HydrophobicContact CD1-CE2 4.27Å; F111-Y115 WeakPolarHBondContact O-CD2 3.31Å; F111-Y115 PolarHBondContact O-N 2.86Å; E112-Y115 PolarHBondContact O-N 2.96Å; E112-Y115 VanDerWaalsContact O-N 3.13Å; V113-Y115 VanDerWaalsContact C-N 3.28Å; V113-Y115 PolarHBondContact O-N 3.01Å; Y115-I117 VanDerWaalsContact C-N 3.32Å; Y115-I117 PolarHBondContact O-N 3.47Å; Y115-P118 WeakPolarHBondContact O-CD 3.19Å; Y115-A119 WeakPolarHBondContact O-CB 3.43Å; Y115-A119 PolarHBondContact O-N 3.47Å
116	I	91.9	Very high	87.5	Confident	89 Å²	89	82.4 Å²	82.4	46%	0.456	44%	0.437	S	S	.	.	H	α-helix	trans	-62.6	-40.3	175.5	-69.8	166.7	0	0	0	110.8	E112 V113 A119 V120	E112-I116 HydrophobicContact CG-CD1 4.14Å; E112-I116 WeakPolarHBondContact O-CG1 3.35Å; E112-I116 PolarHBondContact O-N 3.47Å; V113-I116 PolarHBondContact O-N 3.38Å; I116-A119 PolarHBondContact O-N 3.26Å; I116-V120 HydrophobicContact CG2-CG2 4.03Å; I116-V120 WeakPolarHBondContact O-CG2 3.36Å; I116-V120 PolarHBondContact O-N 3.22Å
117	I	92.3	Very high	88.2	Confident	56 Å²	56	85.5 Å²	85.5	29%	0.287	45%	0.454	S	S	.	.	H	α-helix	trans	-57.2	-57.1	-178.9	-67.2	162.7	0	0	0	111.6	V102 I105 V113 Y115 A119 V120 C121	V102-I117 HydrophobicContact CG2-CG2 4Å; I105-I117 HydrophobicContact CD1-CD1 3.64Å; I105-I117 HydrophobicContact CG2-CD1 4.36Å; V113-I117 HydrophobicContact CG1-CD1 4.3Å; V113-I117 WeakPolarHBondContact O-CG1 3.45Å; V113-I117 PolarHBondContact O-N 2.97Å; Y115-I117 VanDerWaalsContact C-N 3.32Å; Y115-I117 PolarHBondContact O-N 3.47Å; I117-A119 VanDerWaalsContact C-N 3.29Å; I117-A119 PolarHBondContact O-N 3.34Å; I117-V120 PolarHBondContact O-N 3.17Å; I117-C121 PolarHBondContact O-N 3.32Å; I117-C121 PolarHBondContact O-SG 3.06Å; I117-C121 VanDerWaalsContact O-SG 3.32Å
118	P	92	Very high	89.2	Confident	54 Å²	54	87.6 Å²	87.6	35%	0.351	47%	0.47	S	S	.	.	H	α-helix	trans	-58.6	-36.3	174	-25.9	33.7	0	0	0	114.1	V102 G114 Y115 C121 L122	V102-P118 HydrophobicContact CG1-CG 4.17Å; G114-P118 WeakPolarHBondContact O-CD 3.46Å; Y115-P118 WeakPolarHBondContact O-CD 3.19Å; P118-C121 PolarHBondContact O-N 3.41Å; P118-L122 WeakPolarHBondContact O-CB 3.48Å; P118-L122 PolarHBondContact O-N 3.24Å
119	A	92.3	Very high	90	Very high	60 Å²	60	89.5 Å²	89.5	50%	0.496	48%	0.476	S	S	.	.	H	α-helix	trans	-64.7	-43.7	179.7	0	0	0	0	0	112.2	Y115 I116 I117 L122 G123	Y115-A119 WeakPolarHBondContact O-CB 3.43Å; Y115-A119 PolarHBondContact O-N 3.47Å; I116-A119 PolarHBondContact O-N 3.26Å; I117-A119 VanDerWaalsContact C-N 3.29Å; I117-A119 PolarHBondContact O-N 3.34Å; A119-L122 PolarHBondContact O-N 3.04Å; A119-G123 PolarHBondContact O-N 3.45Å
120	V	95.3	Very high	90.8	Very high	79 Å²	79	84.1 Å²	84.1	48%	0.479	46%	0.461	S	S	.	.	H	α-helix	trans	-65.2	-45	175.2	172.8	0	0	0	0	110.7	I116 I117 L122 G123 I124	I116-V120 HydrophobicContact CG2-CG2 4.03Å; I116-V120 WeakPolarHBondContact O-CG2 3.36Å; I116-V120 PolarHBondContact O-N 3.22Å; I117-V120 PolarHBondContact O-N 3.17Å; V120-L122 VanDerWaalsContact C-N 3.31Å; V120-L122 PolarHBondContact O-N 2.84Å; V120-G123 PolarHBondContact O-N 2.95Å; V120-G123 VanDerWaalsContact O-N 3.14Å; V120-I124 HydrophobicContact CG1-CD1 3.86Å; V120-I124 HydrophobicContact CG1-CG1 4.4Å; V120-I124 WeakPolarHBondContact O-CG1 3.47Å; V120-I124 PolarHBondContact O-N 3.45Å
121	C	93.1	Very high	91.6	Very high	76 Å²	76	87.9 Å²	87.9	51%	0.514	48%	0.477	S	S	.	.	H	α-helix	trans	-58.2	-42.4	175.8	-70.6	0	0	0	0	112.2	I117 P118 I124 S125	I117-C121 PolarHBondContact O-N 3.32Å; I117-C121 PolarHBondContact O-SG 3.06Å; I117-C121 VanDerWaalsContact O-SG 3.32Å; P118-C121 PolarHBondContact O-N 3.41Å; C121-I124 PolarHBondContact O-N 3.43Å; C121-S125 WeakPolarHBondContact O-CB 3.31Å; C121-S125 PolarHBondContact O-N 3.07Å
122	L	92.6	Very high	92.1	Very high	133 Å²	133	83.4 Å²	83.4	70%	0.696	46%	0.462	S	S	*	.	H	α-helix	trans	-64.6	-42.4	175.4	-167.9	103.6	0	0	0	111.4	P118 A119 V120 S125 F126	P118-L122 WeakPolarHBondContact O-CB 3.48Å; P118-L122 PolarHBondContact O-N 3.24Å; A119-L122 PolarHBondContact O-N 3.04Å; V120-L122 VanDerWaalsContact C-N 3.31Å; V120-L122 PolarHBondContact O-N 2.84Å; L122-S125 PolarHBondContact O-N 2.91Å; L122-F126 WeakPolarHBondContact O-CB 3.1Å; L122-F126 PolarHBondContact O-N 2.9Å
123	G	94.9	Very high	92.3	Very high	39 Å²	39	84.2 Å²	84.2	40%	0.402	46%	0.459	S	S	.	.	H	α-helix	trans	-61.2	-44.2	176.4	0	0	0	0	0	112.9	A119 V120 F126 L127	A119-G123 PolarHBondContact O-N 3.45Å; V120-G123 PolarHBondContact O-N 2.95Å; V120-G123 VanDerWaalsContact O-N 3.14Å; G123-F126 PolarHBondContact O-N 3.32Å; G123-L127 PolarHBondContact O-N 2.83Å
124	I	96.1	Very high	92.5	Very high	99 Å²	99	86.5 Å²	86.5	51%	0.508	47%	0.473	S	S	.	.	H	α-helix	trans	-63.3	-46.3	174.9	-66.1	167.7	0	0	0	110.4	V120 C121 F126 L127 V128	V120-I124 HydrophobicContact CG1-CD1 3.86Å; V120-I124 HydrophobicContact CG1-CG1 4.4Å; V120-I124 WeakPolarHBondContact O-CG1 3.47Å; V120-I124 PolarHBondContact O-N 3.45Å; C121-I124 PolarHBondContact O-N 3.43Å; I124-F126 VanDerWaalsContact C-N 3.32Å; I124-F126 PolarHBondContact O-N 2.86Å; I124-L127 PolarHBondContact O-N 3.5Å; I124-V128 HydrophobicContact CG2-CG2 4.47Å; I124-V128 WeakPolarHBondContact O-CG2 3.49Å; I124-V128 PolarHBondContact O-N 3.3Å
125	S	92.9	Very high	92.7	Very high	75 Å²	75	92.1 Å²	92.1	52%	0.524	51%	0.507	S	S	.	.	H	α-helix	trans	-58.5	-43.7	177.3	-177.5	0	0	0	0	112	C121 L122 V128 F129	C121-S125 WeakPolarHBondContact O-CB 3.31Å; C121-S125 PolarHBondContact O-N 3.07Å; L122-S125 PolarHBondContact O-N 2.91Å; S125-V128 PolarHBondContact O-N 2.91Å; S125-F129 WeakPolarHBondContact O-CB 3.32Å; S125-F129 PolarHBondContact O-N 3.27Å
126	F	92.8	Very high	92.9	Very high	139 Å²	139	87.8 Å²	87.8	61%	0.61	49%	0.492	S	S	*	.	H	α-helix	trans	-62.7	-43.9	175.5	178.6	-105	0	0	0	112.1	L122 G123 I124 V128 F129 V130	L122-F126 WeakPolarHBondContact O-CB 3.1Å; L122-F126 PolarHBondContact O-N 2.9Å; G123-F126 PolarHBondContact O-N 3.32Å; I124-F126 VanDerWaalsContact C-N 3.32Å; I124-F126 PolarHBondContact O-N 2.86Å; F126-V128 PolarHBondContact O-N 3.24Å; F126-F129 WeakPolarHBondContact O-CB 3.34Å; F126-F129 PolarHBondContact O-N 3.27Å; F126-V130 HydrophobicContact CD1-CG2 4.31Å; F126-V130 HydrophobicContact CD2-CG2 4.42Å; F126-V130 HydrophobicContact CE1-CG2 3.88Å; F126-V130 HydrophobicContact CE2-CG2 3.99Å; F126-V130 HydrophobicContact CZ-CG2 3.7Å; F126-V130 WeakPolarHBondContact O-CG2 3.45Å; F126-V130 PolarHBondContact O-N 3.15Å
127	L	95.8	Very high	92.7	Very high	104 Å²	104	87.2 Å²	87.2	55%	0.545	49%	0.489	S	S	.	.	H	α-helix	trans	-60.3	-46.5	176.7	-176	67.1	0	0	0	111.4	G123 I124 F129 V130 L131	G123-L127 PolarHBondContact O-N 2.83Å; I124-L127 PolarHBondContact O-N 3.5Å; L127-F129 VanDerWaalsContact C-N 3.31Å; L127-F129 PolarHBondContact O-N 3.49Å; L127-V130 PolarHBondContact O-N 3.45Å; L127-L131 HydrophobicContact CG-CD1 4.17Å; L127-L131 VanDerWaalsContact O-CG 3.29Å; L127-L131 WeakPolarHBondContact O-CG 3.23Å; L127-L131 PolarHBondContact O-N 3.41Å
128	V	94.6	Very high	92.2	Very high	93 Å²	93	93 Å²	93	56%	0.564	51%	0.507	S	S	*	.	H	α-helix	trans	-59.6	-42.5	176.1	172.3	0	0	0	0	111	I124 S125 F126 L131 G132	I124-V128 HydrophobicContact CG2-CG2 4.47Å; I124-V128 WeakPolarHBondContact O-CG2 3.49Å; I124-V128 PolarHBondContact O-N 3.3Å; S125-V128 PolarHBondContact O-N 2.91Å; F126-V128 PolarHBondContact O-N 3.24Å; V128-L131 PolarHBondContact O-N 3.01Å; V128-G132 PolarHBondContact O-N 3.02Å
129	F	91.8	Very high	91.5	Very high	97 Å²	97	95.4 Å²	95.4	43%	0.425	51%	0.512	S	S	.	.	H	α-helix	trans	-62.4	-43.2	176.8	-173.6	-93.4	0	0	0	112.2	F67 S125 F126 L127 G132 R133 F136	F67-F129 HydrophobicContact CD1-CE2 4.09Å; F67-F129 AromaticContact CE1-CE2 3.63Å; F67-F129 HydrophobicContact CE1-CE2 3.63Å; F67-F129 HydrophobicContact CE1-CZ 4.02Å; F67-F129 HydrophobicContact CZ-CE2 4.31Å; F67-F129 HydrophobicContact CZ-CZ 4.27Å; S125-F129 WeakPolarHBondContact O-CB 3.32Å; S125-F129 PolarHBondContact O-N 3.27Å; F126-F129 WeakPolarHBondContact O-CB 3.34Å; F126-F129 PolarHBondContact O-N 3.27Å; L127-F129 VanDerWaalsContact C-N 3.31Å; L127-F129 PolarHBondContact O-N 3.49Å; F129-G132 PolarHBondContact O-N 2.02Å; F129-R133 PolarHBondContact O-N 3.17Å; F129-F136 AromaticContact CD2-CE2 3.88Å; F129-F136 HydrophobicContact CD2-CE2 3.88Å; F129-F136 HydrophobicContact CD2-CZ 4.1Å; F129-F136 AromaticContact CE2-CE2 3.85Å; F129-F136 HydrophobicContact CE2-CE2 3.85Å; F129-F136 HydrophobicContact CE2-CZ 4.25Å; F129-F136 HydrophobicContact CG-CE2 4.32Å; F129-F136 HydrophobicContact CZ-CE2 4.27Å; F129-F136 WeakPolarHBondContact O-CE2 3.3Å
130	V	93.2	Very high	90.8	Very high	59 Å²	59	98.3 Å²	98.3	36%	0.358	53%	0.526	S	S	.	.	H	α-helix	trans	-66.2	-40.1	177.6	172.3	0	0	0	0	111.6	F126 L127 G132 R133	F126-V130 HydrophobicContact CD1-CG2 4.31Å; F126-V130 HydrophobicContact CD2-CG2 4.42Å; F126-V130 HydrophobicContact CE1-CG2 3.88Å; F126-V130 HydrophobicContact CE2-CG2 3.99Å; F126-V130 HydrophobicContact CZ-CG2 3.7Å; F126-V130 WeakPolarHBondContact O-CG2 3.45Å; F126-V130 PolarHBondContact O-N 3.15Å; L127-V130 PolarHBondContact O-N 3.45Å; V130-G132 VanDerWaalsContact C-N 3.3Å; V130-G132 PolarHBondContact O-N 3.19Å; V130-R133 VanDerWaalsContact O-CB 3.22Å; V130-R133 WeakPolarHBondContact O-CB 3Å; V130-R133 WeakPolarHBondContact O-CD 3.01Å; V130-R133 WeakPolarHBondContact O-CG 3.1Å; V130-R133 PolarHBondContact O-N 3.48Å
131	L	94.9	Very high	89.8	Confident	122 Å²	122	99.6 Å²	99.6	64%	0.639	55%	0.545	S	S	*	.	H	α-helix	trans	-65.2	-34.6	175.8	-68.4	173.4	0	0	0	111.9	L127 V128 R133	L127-L131 HydrophobicContact CG-CD1 4.17Å; L127-L131 VanDerWaalsContact O-CG 3.29Å; L127-L131 WeakPolarHBondContact O-CG 3.23Å; L127-L131 PolarHBondContact O-N 3.41Å; V128-L131 PolarHBondContact O-N 3.01Å; L131-R133 PolarHBondContact O-N 3.21Å
132	G	91.8	Very high	88.5	Confident	17 Å²	17	104 Å²	104	18%	0.175	56%	0.563	C	S	.	*	G	3₁₀ helix	trans	-71.6	-6.1	176.2	0	0	0	0	0	115.4	V128 F129 V130 T134 V135 F136	V128-G132 PolarHBondContact O-N 3.02Å; F129-G132 PolarHBondContact O-N 2.02Å; V130-G132 VanDerWaalsContact C-N 3.3Å; V130-G132 PolarHBondContact O-N 3.19Å; G132-T134 PolarHBondContact O-N 3.39Å; G132-V135 PolarHBondContact O-N 3.23Å; G132-F136 VanDerWaalsContact O-CD2 3.28Å; G132-F136 WeakPolarHBondContact O-CD2 3.31Å; G132-F136 WeakPolarHBondContact O-CG 3.47Å; G132-F136 PolarHBondContact O-N 2.86Å
133	R	89.4	Confident	87.7	Confident	157 Å²	157	101.1 Å²	101.1	59%	0.592	57%	0.565	S	S	*	*	G	3₁₀ helix	trans	-57.7	-24.7	-171.6	77.7	-179.8	-139.1	175.9	4	115.3	F129 V130 L131 R138	F129-R133 PolarHBondContact O-N 3.17Å; V130-R133 VanDerWaalsContact O-CB 3.22Å; V130-R133 WeakPolarHBondContact O-CB 3Å; V130-R133 WeakPolarHBondContact O-CD 3.01Å; V130-R133 WeakPolarHBondContact O-CG 3.1Å; V130-R133 PolarHBondContact O-N 3.48Å; L131-R133 PolarHBondContact O-N 3.21Å; R133-R138 PolarHBondContact O-NH2 3.22Å
134	T	89.8	Confident	86.8	Confident	120 Å²	120	102 Å²	102	74%	0.736	57%	0.566	S	S	*	*	G	3₁₀ helix	trans	-84.6	-20.7	-179	51.3	0	0	0	0	112.4	G132	G132-T134 PolarHBondContact O-N 3.39Å
135	V	91.5	Very high	85.9	Confident	117 Å²	117	98.4 Å²	98.4	71%	0.709	55%	0.551	S	S	*	*	T	Hydrogen-bonded Turn	trans	-94.7	-26.7	-178.7	-175.7	0	0	0	0	111.3	G132	G132-V135 PolarHBondContact O-N 3.23Å
136	F	91.4	Very high	85.2	Confident	59 Å²	59	98.7 Å²	98.7	26%	0.259	54%	0.542	S	S	.	.	S	Bend	trans	-68.2	134.4	-176.4	-62.8	-42	0	0	0	113.9	F67 Q71 F129 G132 R138	F67-F136 HydrophobicContact CE1-CD1 4.01Å; F67-F136 AromaticContact CE1-CD2 3.99Å; F67-F136 HydrophobicContact CE1-CD2 3.99Å; F67-F136 HydrophobicContact CE1-CE1 4.19Å; F67-F136 HydrophobicContact CE1-CE2 4.15Å; F67-F136 AromaticContact CE1-CG 3.94Å; F67-F136 HydrophobicContact CE1-CG 3.94Å; F67-F136 HydrophobicContact CE1-CZ 4.26Å; F67-F136 HydrophobicContact CZ-CB 3.73Å; F67-F136 HydrophobicContact CZ-CD1 4.07Å; F67-F136 AromaticContact CZ-CD2 3.69Å; F67-F136 HydrophobicContact CZ-CD2 3.69Å; F67-F136 HydrophobicContact CZ-CE2 4.29Å; F67-F136 AromaticContact CZ-CG 3.58Å; F67-F136 HydrophobicContact CZ-CG 3.58Å; Q71-F136 HydrophobicContact CG-CD1 4.44Å; F129-F136 AromaticContact CD2-CE2 3.88Å; F129-F136 HydrophobicContact CD2-CE2 3.88Å; F129-F136 HydrophobicContact CD2-CZ 4.1Å; F129-F136 AromaticContact CE2-CE2 3.85Å; F129-F136 HydrophobicContact CE2-CE2 3.85Å; F129-F136 HydrophobicContact CE2-CZ 4.25Å; F129-F136 HydrophobicContact CG-CE2 4.32Å; F129-F136 HydrophobicContact CZ-CE2 4.27Å; F129-F136 WeakPolarHBondContact O-CE2 3.3Å; G132-F136 VanDerWaalsContact O-CD2 3.28Å; G132-F136 WeakPolarHBondContact O-CD2 3.31Å; G132-F136 WeakPolarHBondContact O-CG 3.47Å; G132-F136 PolarHBondContact O-N 2.86Å; F136-R138 PolarHBondContact O-N 3.5Å
137	I	88.1	Confident	84.7	Confident	77 Å²	77	94.1 Å²	94.1	40%	0.395	53%	0.528	S	S	.	.			trans	-72.7	120	169.5	-56.2	172	0	0	0	108	Q71	Q71-I137 PolarHBondContact NE2-O 3.34Å; Q71-I137 VanDerWaalsContact NE2-O 3.15Å
138	R	81.8	Confident	84	Confident	178 Å²	178	91.2 Å²	91.2	67%	0.672	51%	0.513	S	S	*	.			trans	-104.7	121.4	177.8	-61.6	-177.9	-168.5	179.4	4.2	109.9	R133 F136	R133-R138 PolarHBondContact O-NH2 3.22Å; F136-R138 PolarHBondContact O-N 3.5Å
139	K	76.9	Confident	83.5	Confident	103 Å²	103	87.9 Å²	87.9	45%	0.448	49%	0.491	S	S	.	.	P	Polyproline II helix	trans	-87	148.8	172.6	-68.6	-173.2	-177.3	170.1	0	111	D70	D70-K139 IonicContact OD1-NZ 2.68Å; D70-K139 PolarHBondContact OD1-NZ 2.91Å; D70-K139 WeakPolarHBondContact OD2-CD 3.31Å; D70-K139 WeakPolarHBondContact OD2-CE 3.49Å; D70-K139 IonicContact OD2-NZ 2.92Å; D70-K139 PolarHBondContact OD2-NZ 3.5Å
140	P	79.1	Confident	83.2	Confident	122 Å²	122	87.6 Å²	87.6	79%	0.792	50%	0.497	S	S	*	.	P	Polyproline II helix	trans	-62.5	156.1	170.9	28.4	-34.6	0	0	0	110.9	D142	P140-D142 PolarHBondContact O-N 2.89Å
141	A	73.1	Confident	82.8	Confident	106 Å²	106	90.3 Å²	90.3	88%	0.876	50%	0.504	S	S	*	.	P	Polyproline II helix	trans	-69.9	121.1	-179.6	0	0	0	0	0	111.3	G143	A141-G143 VanDerWaalsContact C-N 3.29Å; A141-G143 PolarHBondContact O-N 2.91Å
142	D	67	Low	82.4	Confident	168 Å²	168	84.5 Å²	84.5	90%	0.898	47%	0.474	S	S	*	.			trans	-91.4	25.1	-174.1	-142.3	8	0	0	0	113.6	P140	P140-D142 PolarHBondContact O-N 2.89Å
143	G	74.5	Confident	82.1	Confident	72 Å²	72	86.8 Å²	86.8	74%	0.742	48%	0.482	S	S	*	.			trans	67.7	-168	-174.3	0	0	0	0	0	113.9	A141	A141-G143 VanDerWaalsContact C-N 3.29Å; A141-G143 PolarHBondContact O-N 2.91Å
144	S	76.4	Confident	81.9	Confident	59 Å²	59	82.4 Å²	82.4	41%	0.413	48%	0.475	S	S	.	.			trans	-122.4	111	179.7	170.9	0	0	0	0	111.5	F146 S147 D148	S144-F146 PolarHBondContact O-N 2.95Å; S144-F146 PolarHBondContact OG-N 3.4Å; S144-S147 WeakPolarHBondContact O-CB 3.47Å; S144-S147 PolarHBondContact O-N 3.39Å; S144-S147 PolarHBondContact OG-N 3.47Å; S144-D148 PolarHBondContact O-N 2.92Å; S144-D148 VanDerWaalsContact O-N 3.09Å
145	A	76.2	Confident	81.6	Confident	23 Å²	23	78.6 Å²	78.6	19%	0.19	45%	0.448	C	S	.	.	H	α-helix	trans	-54.4	-33.6	174.4	0	0	0	0	0	112.6	M149 M368 A371	A145-M149 WeakPolarHBondContact O-CB 3.37Å; A145-M149 PolarHBondContact O-N 3.36Å; A145-M368 HydrophobicContact CB-CE 3.84Å; A145-M368 HydrophobicContact CB-CG 4.06Å; A145-M368 VanDerWaalsContact O-CE 3.29Å; A145-M368 WeakPolarHBondContact O-CE 3.44Å; A145-A371 HydrophobicContact CB-CB 4.09Å
146	F	79	Confident	81.1	Confident	80 Å²	80	73.5 Å²	73.5	35%	0.351	42%	0.418	S	S	.	.	H	α-helix	trans	-70.2	-41.6	176.6	-82.3	-77	0	0	0	112.7	S144 D148 M149 V150 A371 L375	S144-F146 PolarHBondContact O-N 2.95Å; S144-F146 PolarHBondContact OG-N 3.4Å; F146-D148 VanDerWaalsContact C-N 3.35Å; F146-M149 HydrophobicContact CD1-CE 3.74Å; F146-M149 HydrophobicContact CE1-CE 4.08Å; F146-M149 PolarHBondContact O-N 3.14Å; F146-V150 WeakPolarHBondContact O-CG2 3.48Å; F146-V150 PolarHBondContact O-N 3.41Å; F146-A371 HydrophobicContact CD2-CB 4Å; F146-A371 HydrophobicContact CE2-CB 3.63Å; F146-A371 HydrophobicContact CZ-CB 3.91Å; F146-A371 WeakPolarHBondContact CZ-O 3.38Å; F146-L375 HydrophobicContact CE1-CD1 4.4Å; F146-L375 HydrophobicContact CE1-CD2 3.98Å; F146-L375 HydrophobicContact CE1-CG 3.91Å; F146-L375 HydrophobicContact CZ-CD2 4.46Å; F146-L375 HydrophobicContact CZ-CG 4.04Å
147	S	82.8	Confident	80.7	Confident	43 Å²	43	75.4 Å²	75.4	30%	0.301	44%	0.438	S	S	.	.	H	α-helix	trans	-60.9	-46.4	174.7	156.4	0	0	0	0	110.7	S144 M149 V150 K151	S144-S147 WeakPolarHBondContact O-CB 3.47Å; S144-S147 PolarHBondContact O-N 3.39Å; S144-S147 PolarHBondContact OG-N 3.47Å; S147-M149 VanDerWaalsContact C-N 3.31Å; S147-M149 PolarHBondContact O-N 2.8Å; S147-V150 PolarHBondContact O-N 3.17Å; S147-K151 WeakPolarHBondContact O-CB 3.4Å; S147-K151 VanDerWaalsContact O-CG 3.26Å; S147-K151 WeakPolarHBondContact O-CG 3.3Å; S147-K151 PolarHBondContact O-N 2.92Å; S147-K151 WeakPolarHBondContact OG-CE 3.02Å; S147-K151 PolarHBondContact OG-NZ 3.04Å
148	D	80.5	Confident	80.2	Confident	43 Å²	43	76.5 Å²	76.5	23%	0.23	45%	0.451	C	S	.	.	H	α-helix	trans	-59.3	-44.6	176.5	-69.6	-8.6	0	0	0	111	S144 F146 K151 I152 K190	S144-D148 PolarHBondContact O-N 2.92Å; S144-D148 VanDerWaalsContact O-N 3.09Å; F146-D148 VanDerWaalsContact C-N 3.35Å; D148-K151 PolarHBondContact O-N 3.24Å; D148-I152 WeakPolarHBondContact O-CB 3.37Å; D148-I152 WeakPolarHBondContact O-CD1 3.44Å; D148-I152 VanDerWaalsContact O-CG1 3.23Å; D148-I152 WeakPolarHBondContact O-CG1 3.47Å; D148-I152 PolarHBondContact O-N 3.45Å; D148-K190 IonicContact OD2-NZ 2.91Å; D148-K190 PolarHBondContact OD2-NZ 3.13Å
149	M	83.4	Confident	79.6	Confident	24 Å²	24	70.4 Å²	70.4	12%	0.118	44%	0.436	C	S	.	.	H	α-helix	trans	-59.6	-49.5	176.8	-174.5	179.7	75	0	0	112.4	A145 F146 S147 K151 I152 L153 V194 I197 M368	A145-M149 WeakPolarHBondContact O-CB 3.37Å; A145-M149 PolarHBondContact O-N 3.36Å; F146-M149 HydrophobicContact CD1-CE 3.74Å; F146-M149 HydrophobicContact CE1-CE 4.08Å; F146-M149 PolarHBondContact O-N 3.14Å; S147-M149 VanDerWaalsContact C-N 3.31Å; S147-M149 PolarHBondContact O-N 2.8Å; M149-K151 PolarHBondContact O-N 3.02Å; M149-I152 PolarHBondContact O-N 3.4Å; M149-L153 HydrophobicContact CG-CD1 3.83Å; M149-L153 HydrophobicContact CG-CG 4.37Å; M149-L153 WeakPolarHBondContact O-CB 3.24Å; M149-L153 VanDerWaalsContact O-CG 3.23Å; M149-L153 WeakPolarHBondContact O-CG 3.36Å; M149-L153 PolarHBondContact O-N 2.97Å; M149-V194 HydrophobicContact CB-CG2 4.11Å; M149-V194 HydrophobicContact CG-CG1 4.02Å; M149-V194 HydrophobicContact CG-CG2 4.12Å; M149-I197 HydrophobicContact SD-CD1 4.5Å; M149-I197 HydrophobicContact SD-CG2 4.23Å; M149-M368 HydrophobicContact CB-CE 4.38Å
150	V	85.8	Confident	78.7	Confident	90 Å²	90	74 Å²	74	55%	0.545	46%	0.455	S	S	.	.	H	α-helix	trans	-64.4	-41.4	-179.8	171.8	0	0	0	0	111.1	F146 S147 L153 S154	F146-V150 WeakPolarHBondContact O-CG2 3.48Å; F146-V150 PolarHBondContact O-N 3.41Å; S147-V150 PolarHBondContact O-N 3.17Å; V150-L153 PolarHBondContact O-N 3.43Å; V150-S154 WeakPolarHBondContact O-CB 3.42Å; V150-S154 PolarHBondContact O-N 3.3Å
151	K	86.4	Confident	77.8	Confident	116 Å²	116	77.4 Å²	77.4	50%	0.504	46%	0.457	S	S	.	.	H	α-helix	trans	-62.3	-43.9	176.5	-73.4	172.9	-175.6	174.9	0	111.9	S147 D148 M149 F155 F186	S147-K151 WeakPolarHBondContact O-CB 3.4Å; S147-K151 VanDerWaalsContact O-CG 3.26Å; S147-K151 WeakPolarHBondContact O-CG 3.3Å; S147-K151 PolarHBondContact O-N 2.92Å; S147-K151 WeakPolarHBondContact OG-CE 3.02Å; S147-K151 PolarHBondContact OG-NZ 3.04Å; D148-K151 PolarHBondContact O-N 3.24Å; M149-K151 PolarHBondContact O-N 3.02Å; K151-F155 VanDerWaalsContact O-CB 3.24Å; K151-F155 WeakPolarHBondContact O-CB 3.32Å; K151-F155 PolarHBondContact O-N 3.09Å; K151-F186 HydrophobicContact CB-CE1 4.08Å; K151-F186 HydrophobicContact CB-CZ 3.85Å
152	I	85.4	Confident	76.9	Confident	1 Å²	1	74.9 Å²	74.9	1%	0.005	43%	0.431	C	S	.	.	H	α-helix	trans	-66.5	-45.4	178.4	-70.7	165.5	0	0	0	110.7	D148 M149 F155 A156 A178 F186 K190 V191 V194	D148-I152 WeakPolarHBondContact O-CB 3.37Å; D148-I152 WeakPolarHBondContact O-CD1 3.44Å; D148-I152 VanDerWaalsContact O-CG1 3.23Å; D148-I152 WeakPolarHBondContact O-CG1 3.47Å; D148-I152 PolarHBondContact O-N 3.45Å; M149-I152 PolarHBondContact O-N 3.4Å; I152-F155 PolarHBondContact O-N 2.58Å; I152-A156 VanDerWaalsContact O-CB 3.25Å; I152-A156 WeakPolarHBondContact O-CB 2.99Å; I152-A156 PolarHBondContact O-N 2.84Å; I152-A178 HydrophobicContact CG2-CB 3.99Å; I152-F186 HydrophobicContact CD1-CB 4.35Å; I152-F186 HydrophobicContact CD1-CD1 4.16Å; I152-F186 HydrophobicContact CD1-CG 4.2Å; I152-F186 HydrophobicContact CG1-CB 4.13Å; I152-F186 HydrophobicContact CG1-CD1 3.63Å; I152-F186 HydrophobicContact CG1-CD2 3.78Å; I152-F186 HydrophobicContact CG1-CE1 3.92Å; I152-F186 HydrophobicContact CG1-CE2 4.05Å; I152-F186 HydrophobicContact CG1-CG 3.55Å; I152-F186 HydrophobicContact CG1-CZ 4.13Å; I152-K190 HydrophobicContact CD1-CB 4.11Å; I152-V191 HydrophobicContact CD1-CG2 4.41Å; I152-V191 HydrophobicContact CG2-CG2 4.35Å; I152-V194 HydrophobicContact CB-CG2 4.43Å; I152-V194 HydrophobicContact CD1-CG2 3.83Å; I152-V194 HydrophobicContact CG2-CB 4.43Å; I152-V194 HydrophobicContact CG2-CG1 4.28Å; I152-V194 HydrophobicContact CG2-CG2 4.44Å
153	L	85.5	Confident	76.2	Confident	64 Å²	64	76.9 Å²	76.9	34%	0.335	43%	0.432	S	S	.	.	H	α-helix	trans	-63.7	-44.9	177.7	-71.3	172.8	0	0	0	111.8	M149 V150 A156 C157 L175 V194 V198	M149-L153 HydrophobicContact CG-CD1 3.83Å; M149-L153 HydrophobicContact CG-CG 4.37Å; M149-L153 WeakPolarHBondContact O-CB 3.24Å; M149-L153 VanDerWaalsContact O-CG 3.23Å; M149-L153 WeakPolarHBondContact O-CG 3.36Å; M149-L153 PolarHBondContact O-N 2.97Å; V150-L153 PolarHBondContact O-N 3.43Å; L153-A156 PolarHBondContact O-N 3.02Å; L153-C157 VanDerWaalsContact O-CB 3.28Å; L153-C157 WeakPolarHBondContact O-CB 3.34Å; L153-C157 PolarHBondContact O-N 3.49Å; L153-L175 HydrophobicContact CD2-CD2 3.78Å; L153-V194 HydrophobicContact CD2-CG1 4.25Å; L153-V194 HydrophobicContact CG-CG1 4.32Å; L153-V198 HydrophobicContact CD2-CG2 4.21Å
154	S	85.3	Confident	75.3	Confident	65 Å²	65	82 Å²	82	46%	0.455	44%	0.437	S	S	.	.	H	α-helix	trans	-63.1	-45.3	177	175.7	0	0	0	0	111.3	V150 A156 C157 C158	V150-S154 WeakPolarHBondContact O-CB 3.42Å; V150-S154 PolarHBondContact O-N 3.3Å; S154-A156 PolarHBondContact O-N 3.27Å; S154-C157 PolarHBondContact O-N 2.9Å; S154-C158 VanDerWaalsContact O-CB 3.26Å; S154-C158 WeakPolarHBondContact O-CB 3.27Å; S154-C158 PolarHBondContact O-N 3.48Å
155	F	83.9	Confident	74.2	Confident	41 Å²	41	83.5 Å²	83.5	18%	0.18	45%	0.445	C	S	.	.	H	α-helix	trans	-61.7	-45.1	176	-175.4	-91.2	0	0	0	111.6	K151 I152 C157 S159 A178 K185 F186	K151-F155 VanDerWaalsContact O-CB 3.24Å; K151-F155 WeakPolarHBondContact O-CB 3.32Å; K151-F155 PolarHBondContact O-N 3.09Å; I152-F155 PolarHBondContact O-N 2.58Å; F155-C157 VanDerWaalsContact C-N 3.3Å; F155-C157 PolarHBondContact O-N 3.35Å; F155-S159 WeakPolarHBondContact O-CA 3.31Å; F155-S159 WeakPolarHBondContact O-CB 3.24Å; F155-S159 PolarHBondContact O-N 3.18Å; F155-A178 HydrophobicContact CD1-CB 3.9Å; F155-K185 HydrophobicContact CE2-CD 4.14Å; F155-K185 HydrophobicContact CE2-CG 4.11Å; F155-K185 HydrophobicContact CZ-CG 4.4Å; F155-F186 HydrophobicContact CB-CE2 3.78Å; F155-F186 HydrophobicContact CD1-CE2 4.34Å; F155-F186 HydrophobicContact CD2-CE2 4.45Å; F155-F186 AromaticContact CG-CE2 3.94Å; F155-F186 HydrophobicContact CG-CE2 3.94Å
156	A	81.5	Confident	73.1	Confident	9 Å²	9	89.9 Å²	89.9	7%	0.074	48%	0.476	C	S	.	.	H	α-helix	trans	-67.2	-31.5	-179.5	0	0	0	0	0	112.8	I152 L153 S154 L174 L175 A178	I152-A156 VanDerWaalsContact O-CB 3.25Å; I152-A156 WeakPolarHBondContact O-CB 2.99Å; I152-A156 PolarHBondContact O-N 2.84Å; L153-A156 PolarHBondContact O-N 3.02Å; S154-A156 PolarHBondContact O-N 3.27Å; A156-L174 HydrophobicContact CB-CD2 3.7Å; A156-L174 WeakPolarHBondContact O-CD2 3.21Å; A156-L175 HydrophobicContact CB-CD2 3.84Å; A156-A178 HydrophobicContact CB-CB 4.48Å
157	C	81.7	Confident	72	Confident	99 Å²	99	93.7 Å²	93.7	67%	0.669	50%	0.499	S	S	*	.	H	α-helix	trans	-83.7	-36.1	179.5	-167.2	0	0	0	0	113.5	L153 S154 F155	L153-C157 VanDerWaalsContact O-CB 3.28Å; L153-C157 WeakPolarHBondContact O-CB 3.34Å; L153-C157 PolarHBondContact O-N 3.49Å; S154-C157 PolarHBondContact O-N 2.9Å; F155-C157 VanDerWaalsContact C-N 3.3Å; F155-C157 PolarHBondContact O-N 3.35Å
158	C	78.6	Confident	70.4	Confident	101 Å²	101	99.9 Å²	99.9	68%	0.682	53%	0.528	S	S	*	.	H	α-helix	trans	-107.1	-11.9	-170.6	-59	0	0	0	0	114.2	S154	S154-C158 VanDerWaalsContact O-CB 3.26Å; S154-C158 WeakPolarHBondContact O-CB 3.27Å; S154-C158 PolarHBondContact O-N 3.48Å
159	S	68.9	Low	69.2	Low	49 Å²	49	107.1 Å²	107.1	34%	0.343	55%	0.552	S	S	.	*	S	Bend	trans	-77	139.2	177	-169.8	0	0	0	0	111.2	F155	F155-S159 WeakPolarHBondContact O-CA 3.31Å; F155-S159 WeakPolarHBondContact O-CB 3.24Å; F155-S159 PolarHBondContact O-N 3.18Å
160	Q	58.8	Low	68	Low	180 Å²	180	112.8 Å²	112.8	84%	0.841	58%	0.583	S	S	*	*	P	Polyproline II helix	trans	-59.8	142	165.8	-75	176.9	-7.7	0	0	109.5
161	K	59	Low	66.7	Low	193 Å²	193	118.2 Å²	118.2	84%	0.839	60%	0.599	S	S	*	*	P	Polyproline II helix	trans	-54.5	133.6	179.6	-70.1	-179	-179.5	176.1	0	109.8
162	P	55	Low	65.7	Low	53 Å²	53	115.6 Å²	115.6	34%	0.344	59%	0.594	S	S	.	*	P	Polyproline II helix	trans	-59.4	144.7	177.1	-17.8	27.6	0	0	0	110.9	E164 T177 Y182	P162-E164 PolarHBondContact O-N 3.37Å; P162-T177 VanDerWaalsContact CD-CG2 3.41Å; P162-T177 HydrophobicContact CG-CG2 3.62Å; P162-Y182 WeakPolarHBondContact CB-O 3.42Å; P162-Y182 WeakPolarHBondContact CG-O 3.37Å
163	K	52.3	Low	65.1	Low	210 Å²	210	119.2 Å²	119.2	91%	0.913	62%	0.616	S	S	*	*	S	Bend	trans	-67.2	119.7	170.1	-77.7	179.5	175.5	179.5	0	108.9
164	E	55.1	Low	64.7	Low	179 Å²	179	121.7 Å²	121.7	84%	0.836	63%	0.629	S	S	*	*			trans	34	124.4	177	-72.1	-158.4	142.2	0	0	120.1	P162 N166	P162-E164 PolarHBondContact O-N 3.37Å; E164-N166 PolarHBondContact O-N 3.38Å
165	P	53.3	Low	64.4	Low	91 Å²	91	119.7 Å²	119.7	59%	0.591	61%	0.613	S	S	*	*			trans	-75	120.5	166.2	30.2	-28.1	0	0	0	109.8	L167	P165-L167 PolarHBondContact O-N 3.34Å
166	N	53.3	Low	64.2	Low	157 Å²	157	118.4 Å²	118.4	84%	0.84	61%	0.608	S	S	*	*			trans	-52.9	131.3	166	-82.5	-44.2	0	0	0	109.8	E164 L168	E164-N166 PolarHBondContact O-N 3.38Å; N166-L168 PolarHBondContact O-N 2.95Å
167	L	55.5	Low	64	Low	160 Å²	160	119.2 Å²	119.2	84%	0.838	61%	0.612	S	S	*	*	S	Bend	trans	-45.7	117.3	-177.3	-79.7	84.3	0	0	0	111.7	P165	P165-L167 PolarHBondContact O-N 3.34Å
168	L	50	Low	63.8	Low	173 Å²	173	114.5 Å²	114.5	91%	0.906	58%	0.58	S	S	*	*	S	Bend	trans	152.7	27.8	147.9	-84.4	156.2	0	0	0	115.3	N166	N166-L168 PolarHBondContact O-N 2.95Å
169	R	54.8	Low	64	Low	195 Å²	195	110.5 Å²	110.5	74%	0.736	55%	0.551	S	S	*	*	S	Bend	trans	-147.5	151.5	173.3	-138.1	160.7	-177.8	179.6	-1.7	116.3
170	N	57.6	Low	64.5	Low	143 Å²	143	113.3 Å²	113.3	77%	0.765	56%	0.562	S	S	*	*			trans	-41	148	178.9	-73.3	-21.8	0	0	0	112.9	P172	N170-P172 VanDerWaalsContact O-N 3.09Å
171	K	57.9	Low	65.2	Low	203 Å²	203	109 Å²	109	88%	0.883	55%	0.548	S	S	*	.			trans	-44.5	117.1	177.5	-76.3	-176	176.8	-178.7	0	110.6
172	P	65.7	Low	65.7	Low	62 Å²	62	101.8 Å²	101.8	40%	0.403	52%	0.516	S	S	.	.			trans	-67.9	137.7	-176.5	25	-31.8	0	0	0	110.6	N170 D176 Y182	N170-P172 VanDerWaalsContact O-N 3.09Å; P172-D176 HydrophobicContact CB-CB 3.68Å; P172-Y182 HydrophobicContact CB-CD1 4.36Å; P172-Y182 HydrophobicContact CB-CE1 3.97Å; P172-Y182 HydrophobicContact CG-CE1 4.32Å
173	T	72.8	Confident	66.5	Low	77 Å²	77	102.3 Å²	102.3	47%	0.472	53%	0.53	S	S	.	.			trans	-72	159.5	166.4	54.7	0	0	0	0	110.2	L175 D176 K195	T173-L175 PolarHBondContact O-N 3.32Å; T173-D176 WeakPolarHBondContact CB-OD2 3.42Å; T173-D176 PolarHBondContact N-OD2 3.03Å; T173-D176 WeakPolarHBondContact O-CA 3.23Å; T173-D176 VanDerWaalsContact O-CB 3.27Å; T173-D176 WeakPolarHBondContact O-CB 3.46Å; T173-D176 PolarHBondContact O-N 3.5Å; T173-D176 PolarHBondContact OG1-OD2 2.81Å; T173-K195 WeakPolarHBondContact OG1-CE 3.14Å; T173-K195 PolarHBondContact OG1-NZ 3.39Å
174	L	77.6	Confident	67.8	Low	115 Å²	115	92.7 Å²	92.7	60%	0.602	49%	0.491	S	S	*	.	G	3₁₀ helix	trans	-52.3	-34.5	178.9	-175.9	152.6	0	0	0	112.4	A156 T177	A156-L174 HydrophobicContact CB-CD2 3.7Å; A156-L174 WeakPolarHBondContact O-CD2 3.21Å; L174-T177 WeakPolarHBondContact O-CB 3.25Å; L174-T177 PolarHBondContact O-OG1 3.17Å
175	L	80	Confident	69.1	Low	23 Å²	23	91.9 Å²	91.9	12%	0.12	49%	0.485	C	S	.	.	G	3₁₀ helix	trans	-75.4	-23.1	176.6	-64.2	169.6	0	0	0	113.6	L153 A156 T173 T177 A178 V191 K195 V198	L153-L175 HydrophobicContact CD2-CD2 3.78Å; A156-L175 HydrophobicContact CB-CD2 3.84Å; T173-L175 PolarHBondContact O-N 3.32Å; L175-T177 PolarHBondContact O-N 3.28Å; L175-A178 WeakPolarHBondContact O-CB 3.46Å; L175-A178 PolarHBondContact O-N 2.88Å; L175-V191 WeakPolarHBondContact O-CG1 3.36Å; L175-K195 HydrophobicContact CB-CD 4.35Å; L175-K195 HydrophobicContact CB-CG 3.83Å; L175-K195 HydrophobicContact CD1-CG 3.63Å; L175-K195 HydrophobicContact CG-CG 4.37Å; L175-V198 HydrophobicContact CD1-CB 4.5Å; L175-V198 HydrophobicContact CD1-CG2 4.26Å
176	D	79.5	Confident	70.6	Confident	15 Å²	15	89.3 Å²	89.3	8%	0.08	46%	0.464	C	S	.	.	G	3₁₀ helix	trans	-63	-28.3	174.9	-78.4	-58.7	0	0	0	112.4	P172 T173 A178 K179 Y182 K195	P172-D176 HydrophobicContact CB-CB 3.68Å; T173-D176 WeakPolarHBondContact CB-OD2 3.42Å; T173-D176 PolarHBondContact N-OD2 3.03Å; T173-D176 WeakPolarHBondContact O-CA 3.23Å; T173-D176 VanDerWaalsContact O-CB 3.27Å; T173-D176 WeakPolarHBondContact O-CB 3.46Å; T173-D176 PolarHBondContact O-N 3.5Å; T173-D176 PolarHBondContact OG1-OD2 2.81Å; D176-A178 PolarHBondContact O-N 3.36Å; D176-A178 VanDerWaalsContact O-N 3.14Å; D176-K179 WeakPolarHBondContact O-CB 3.44Å; D176-K179 WeakPolarHBondContact O-CG 3.47Å; D176-K179 PolarHBondContact O-N 2.92Å; D176-K179 WeakPolarHBondContact OD1-CE 3.48Å; D176-K179 IonicContact OD1-NZ 2.67Å; D176-K179 PolarHBondContact OD1-NZ 3.26Å; D176-Y182 HydrophobicContact CB-CD2 4.06Å; D176-Y182 HydrophobicContact CB-CE2 3.98Å; D176-Y182 VanDerWaalsContact O-CD2 3.27Å; D176-Y182 WeakPolarHBondContact O-CD2 3.38Å; D176-K195 IonicContact OD1-NZ 3.26Å; D176-K195 PolarHBondContact OD1-NZ 3.37Å; D176-K195 IonicContact OD2-NZ 3.44Å; D176-K195 PolarHBondContact OD2-NZ 2.92Å
177	T	75.8	Confident	72.1	Confident	25 Å²	25	85 Å²	85	15%	0.153	45%	0.445	C	S	.	.	G	3₁₀ helix	trans	-58.3	-24.1	175.4	-60.3	0	0	0	0	113.2	P162 L174 L175 K179 G184	P162-T177 VanDerWaalsContact CD-CG2 3.41Å; P162-T177 HydrophobicContact CG-CG2 3.62Å; L174-T177 WeakPolarHBondContact O-CB 3.25Å; L174-T177 PolarHBondContact O-OG1 3.17Å; L175-T177 PolarHBondContact O-N 3.28Å; T177-K179 VanDerWaalsContact C-N 3.32Å; T177-G184 WeakPolarHBondContact O-CA 3.42Å
178	A	79.4	Confident	73.5	Confident	0 Å²	0	81 Å²	81	0%	0	42%	0.422	C	S	.	.	G	3₁₀ helix	trans	-77.5	-15	177.8	0	0	0	0	0	114	I152 F155 A156 L175 D176 G184 K185 F186 V191	I152-A178 HydrophobicContact CG2-CB 3.99Å; F155-A178 HydrophobicContact CD1-CB 3.9Å; A156-A178 HydrophobicContact CB-CB 4.48Å; L175-A178 WeakPolarHBondContact O-CB 3.46Å; L175-A178 PolarHBondContact O-N 2.88Å; D176-A178 PolarHBondContact O-N 3.36Å; D176-A178 VanDerWaalsContact O-N 3.14Å; A178-G184 CarbonylContact O-C 3.51Å; A178-G184 WeakPolarHBondContact O-CA 3.37Å; A178-K185 PolarHBondContact O-N 2.92Å; A178-F186 HydrophobicContact CB-CD2 4.08Å; A178-F186 WeakPolarHBondContact O-CB 3.27Å; A178-F186 PolarHBondContact O-N 3.4Å; A178-V191 HydrophobicContact CB-CG2 4.08Å
179	K	82.5	Confident	75.2	Confident	17 Å²	17	79.5 Å²	79.5	7%	0.074	41%	0.41	C	S	.	.	B	Isolated β-bridge	trans	-74	144	-178.5	-61.9	176.3	169.4	175.7	0	111.5	D176 T177 T181 Y182 G183 G184 F186 E188 V191 E192	D176-K179 WeakPolarHBondContact O-CB 3.44Å; D176-K179 WeakPolarHBondContact O-CG 3.47Å; D176-K179 PolarHBondContact O-N 2.92Å; D176-K179 WeakPolarHBondContact OD1-CE 3.48Å; D176-K179 IonicContact OD1-NZ 2.67Å; D176-K179 PolarHBondContact OD1-NZ 3.26Å; T177-K179 VanDerWaalsContact C-N 3.32Å; K179-T181 PolarHBondContact O-N 3.4Å; K179-T181 VanDerWaalsContact O-N 3.15Å; K179-Y182 HydrophobicContact CB-CD2 4.13Å; K179-Y182 HydrophobicContact CD-CD2 4.11Å; K179-Y182 HydrophobicContact CD-CE2 4.21Å; K179-Y182 PolarHBondContact O-N 2.92Å; K179-G183 PolarHBondContact O-N 3.21Å; K179-G184 WeakPolarHBondContact O-CA 3.33Å; K179-G184 PolarHBondContact O-N 3.35Å; K179-F186 CarbonylContact C-O 3.56Å; K179-F186 WeakPolarHBondContact CA-O 3.45Å; K179-E188 HydrophobicContact CB-CG 4.45Å; K179-E188 HydrophobicContact CD-CG 4.2Å; K179-E188 HydrophobicContact CG-CG 4.46Å; K179-V191 HydrophobicContact CD-CG1 4.48Å; K179-V191 HydrophobicContact CG-CB 3.81Å; K179-V191 HydrophobicContact CG-CG1 3.78Å; K179-V191 HydrophobicContact CG-CG2 3.88Å; K179-E192 WeakPolarHBondContact CE-OE1 3.29Å; K179-E192 IonicContact NZ-OE1 3.38Å; K179-E192 PolarHBondContact NZ-OE1 3.09Å
180	L	79.4	Confident	76.5	Confident	109 Å²	109	73.5 Å²	73.5	57%	0.571	39%	0.389	S	S	*	.	G	3₁₀ helix	trans	-48.6	-40.4	171.1	-74.3	165	0	0	0	112.6	Y182 G183 G184 F186	L180-Y182 PolarHBondContact O-N 3.11Å; L180-G183 PolarHBondContact O-N 3.13Å; L180-G184 WeakPolarHBondContact CA-O 3.49Å; L180-G184 WeakPolarHBondContact CD2-O 3.46Å; L180-F186 WeakPolarHBondContact CG-O 3.48Å; L180-F186 PolarHBondContact N-O 3.31Å
181	T	72.2	Confident	77.8	Confident	88 Å²	88	66.7 Å²	66.7	54%	0.54	35%	0.353	S	S	.	.	G	3₁₀ helix	trans	-63.6	-23.5	-178.5	-37.7	0	0	0	0	113.9	K179 E188	K179-T181 PolarHBondContact O-N 3.4Å; K179-T181 VanDerWaalsContact O-N 3.15Å; T181-E188 WeakPolarHBondContact CB-OE1 3.31Å; T181-E188 PolarHBondContact OG1-OE1 2.9Å
182	Y	70.3	Confident	79.1	Confident	43 Å²	43	60.4 Å²	60.4	17%	0.169	33%	0.327	C	S	.	.	G	3₁₀ helix	trans	-107.5	17.4	176.5	-67.4	-81.9	0	0	0	111.9	P162 P172 D176 K179 L180	P162-Y182 WeakPolarHBondContact CB-O 3.42Å; P162-Y182 WeakPolarHBondContact CG-O 3.37Å; P172-Y182 HydrophobicContact CB-CD1 4.36Å; P172-Y182 HydrophobicContact CB-CE1 3.97Å; P172-Y182 HydrophobicContact CG-CE1 4.32Å; D176-Y182 HydrophobicContact CB-CD2 4.06Å; D176-Y182 HydrophobicContact CB-CE2 3.98Å; D176-Y182 VanDerWaalsContact O-CD2 3.27Å; D176-Y182 WeakPolarHBondContact O-CD2 3.38Å; K179-Y182 HydrophobicContact CB-CD2 4.13Å; K179-Y182 HydrophobicContact CD-CD2 4.11Å; K179-Y182 HydrophobicContact CD-CE2 4.21Å; K179-Y182 PolarHBondContact O-N 2.92Å; L180-Y182 PolarHBondContact O-N 3.11Å
183	G	71	Confident	80.1	Confident	63 Å²	63	58.3 Å²	58.3	65%	0.649	31%	0.312	S	S	*	.	T	Hydrogen-bonded Turn	trans	83.5	11.2	-179	0	0	0	0	0	114.8	K179 L180	K179-G183 PolarHBondContact O-N 3.21Å; L180-G183 PolarHBondContact O-N 3.13Å
184	G	79.6	Confident	80.8	Confident	8 Å²	8	54.7 Å²	54.7	8%	0.082	29%	0.289	C	S	.	.			trans	-81.5	-176.2	173.4	0	0	0	0	0	113.5	T177 A178 K179 L180	T177-G184 WeakPolarHBondContact O-CA 3.42Å; A178-G184 CarbonylContact O-C 3.51Å; A178-G184 WeakPolarHBondContact O-CA 3.37Å; K179-G184 WeakPolarHBondContact O-CA 3.33Å; K179-G184 PolarHBondContact O-N 3.35Å; L180-G184 WeakPolarHBondContact CA-O 3.49Å; L180-G184 WeakPolarHBondContact CD2-O 3.46Å
185	K	83.2	Confident	81.2	Confident	162 Å²	162	50 Å²	50	70%	0.704	26%	0.264	S	S	*	.	S	Bend	trans	-103	-7.1	-175	-65.9	-175.6	178.3	-178.1	0	114.5	F155 A178	F155-K185 HydrophobicContact CE2-CD 4.14Å; F155-K185 HydrophobicContact CE2-CG 4.11Å; F155-K185 HydrophobicContact CZ-CG 4.4Å; A178-K185 PolarHBondContact O-N 2.92Å
186	F	85.1	Confident	81.3	Confident	37 Å²	37	50.6 Å²	50.6	16%	0.162	27%	0.271	C	S	.	.	B	Isolated β-bridge	trans	-113	144.1	-166.3	-58.3	-82.3	0	0	0	112.7	K151 I152 F155 A178 K179 L180 V191	K151-F186 HydrophobicContact CB-CE1 4.08Å; K151-F186 HydrophobicContact CB-CZ 3.85Å; I152-F186 HydrophobicContact CD1-CB 4.35Å; I152-F186 HydrophobicContact CD1-CD1 4.16Å; I152-F186 HydrophobicContact CD1-CG 4.2Å; I152-F186 HydrophobicContact CG1-CB 4.13Å; I152-F186 HydrophobicContact CG1-CD1 3.63Å; I152-F186 HydrophobicContact CG1-CD2 3.78Å; I152-F186 HydrophobicContact CG1-CE1 3.92Å; I152-F186 HydrophobicContact CG1-CE2 4.05Å; I152-F186 HydrophobicContact CG1-CG 3.55Å; I152-F186 HydrophobicContact CG1-CZ 4.13Å; F155-F186 HydrophobicContact CB-CE2 3.78Å; F155-F186 HydrophobicContact CD1-CE2 4.34Å; F155-F186 HydrophobicContact CD2-CE2 4.45Å; F155-F186 AromaticContact CG-CE2 3.94Å; F155-F186 HydrophobicContact CG-CE2 3.94Å; A178-F186 HydrophobicContact CB-CD2 4.08Å; A178-F186 WeakPolarHBondContact O-CB 3.27Å; A178-F186 PolarHBondContact O-N 3.4Å; K179-F186 CarbonylContact C-O 3.56Å; K179-F186 WeakPolarHBondContact CA-O 3.45Å; L180-F186 WeakPolarHBondContact CG-O 3.48Å; L180-F186 PolarHBondContact N-O 3.31Å; F186-V191 HydrophobicContact CB-CG2 3.8Å
187	P	85.3	Confident	81.6	Confident	66 Å²	66	49.9 Å²	49.9	43%	0.429	27%	0.267	S	S	.	.			trans	-57.2	146.8	172.7	-21.6	31.8	0	0	0	112	E189 K190 V191	P187-E189 VanDerWaalsContact C-N 3.28Å; P187-E189 PolarHBondContact O-N 3.43Å; P187-K190 HydrophobicContact CB-CG 4.43Å; P187-K190 HydrophobicContact CG-CG 4.38Å; P187-K190 PolarHBondContact O-N 3.39Å; P187-V191 PolarHBondContact O-N 3.31Å
188	E	84.3	Confident	82.1	Confident	76 Å²	76	51.1 Å²	51.1	36%	0.355	27%	0.274	S	S	.	.	H	α-helix	trans	-58.7	-40.1	-179.2	-65	-162.6	157.3	0	0	112.7	K179 T181 V191 E192	K179-E188 HydrophobicContact CB-CG 4.45Å; K179-E188 HydrophobicContact CD-CG 4.2Å; K179-E188 HydrophobicContact CG-CG 4.46Å; T181-E188 WeakPolarHBondContact CB-OE1 3.31Å; T181-E188 PolarHBondContact OG1-OE1 2.9Å; E188-V191 PolarHBondContact O-N 3.47Å; E188-E192 PolarHBondContact O-N 3.07Å
189	E	84.8	Confident	82.4	Confident	143 Å²	143	58.3 Å²	58.3	67%	0.668	31%	0.305	S	S	*	.	H	α-helix	trans	-56.2	-53.7	178.8	-175	174.6	-163.4	0	0	110.9	P187 V191 E192 E193	P187-E189 VanDerWaalsContact C-N 3.28Å; P187-E189 PolarHBondContact O-N 3.43Å; E189-V191 VanDerWaalsContact C-N 3.28Å; E189-V191 PolarHBondContact O-N 3.13Å; E189-E192 PolarHBondContact O-N 2.94Å; E189-E192 VanDerWaalsContact O-N 3.13Å; E189-E193 VanDerWaalsContact O-CG 3.27Å; E189-E193 WeakPolarHBondContact O-CG 3.44Å; E189-E193 PolarHBondContact O-N 3.21Å
190	K	83.6	Confident	82.5	Confident	68 Å²	68	57.8 Å²	57.8	30%	0.296	30%	0.303	S	S	.	.	H	α-helix	trans	-58.5	-37.2	178.9	-70.9	-72.6	-174.3	164.1	0	113	D148 I152 P187 V194	D148-K190 IonicContact OD2-NZ 2.91Å; D148-K190 PolarHBondContact OD2-NZ 3.13Å; I152-K190 HydrophobicContact CD1-CB 4.11Å; P187-K190 HydrophobicContact CB-CG 4.43Å; P187-K190 HydrophobicContact CG-CG 4.38Å; P187-K190 PolarHBondContact O-N 3.39Å; K190-V194 WeakPolarHBondContact O-CG2 3.15Å; K190-V194 PolarHBondContact O-N 3.3Å
191	V	84.8	Confident	83	Confident	1 Å²	1	54.8 Å²	54.8	1%	0.006	29%	0.287	C	S	.	.	H	α-helix	trans	-71.9	-39.9	178.1	177.4	0	0	0	0	111.6	I152 L175 A178 K179 F186 P187 E188 E189 E193 V194 K195	I152-V191 HydrophobicContact CD1-CG2 4.41Å; I152-V191 HydrophobicContact CG2-CG2 4.35Å; L175-V191 WeakPolarHBondContact O-CG1 3.36Å; A178-V191 HydrophobicContact CB-CG2 4.08Å; K179-V191 HydrophobicContact CD-CG1 4.48Å; K179-V191 HydrophobicContact CG-CB 3.81Å; K179-V191 HydrophobicContact CG-CG1 3.78Å; K179-V191 HydrophobicContact CG-CG2 3.88Å; F186-V191 HydrophobicContact CB-CG2 3.8Å; P187-V191 PolarHBondContact O-N 3.31Å; E188-V191 PolarHBondContact O-N 3.47Å; E189-V191 VanDerWaalsContact C-N 3.28Å; E189-V191 PolarHBondContact O-N 3.13Å; V191-E193 VanDerWaalsContact C-N 3.33Å; V191-V194 PolarHBondContact O-N 3.45Å; V191-K195 WeakPolarHBondContact O-CG 3.16Å; V191-K195 PolarHBondContact O-N 3.01Å
192	E	85	Confident	83.8	Confident	70 Å²	70	54.5 Å²	54.5	33%	0.327	29%	0.287	S	S	.	.	H	α-helix	trans	-68.4	-33.1	175.8	-71.4	-56.7	142.7	0	0	112.5	K179 E188 E189 K195 S196	K179-E192 WeakPolarHBondContact CE-OE1 3.29Å; K179-E192 IonicContact NZ-OE1 3.38Å; K179-E192 PolarHBondContact NZ-OE1 3.09Å; E188-E192 PolarHBondContact O-N 3.07Å; E189-E192 PolarHBondContact O-N 2.94Å; E189-E192 VanDerWaalsContact O-N 3.13Å; E192-K195 PolarHBondContact O-N 3.47Å; E192-K195 IonicContact OE1-NZ 3.9Å; E192-K195 PolarHBondContact OE1-NZ 2.9Å; E192-S196 PolarHBondContact O-N 3.14Å; E192-S196 PolarHBondContact O-OG 3.2Å
193	E	86.7	Confident	84.6	Confident	19 Å²	19	53.4 Å²	53.4	9%	0.089	29%	0.285	C	S	.	.	H	α-helix	trans	-59.3	-50.6	171.4	-71.1	179.6	162.9	0	0	111.5	E189 V191 K195 S196 I197 P365 S367 M368	E189-E193 VanDerWaalsContact O-CG 3.27Å; E189-E193 WeakPolarHBondContact O-CG 3.44Å; E189-E193 PolarHBondContact O-N 3.21Å; V191-E193 VanDerWaalsContact C-N 3.33Å; E193-K195 PolarHBondContact O-N 3.42Å; E193-S196 WeakPolarHBondContact O-CB 3.3Å; E193-S196 PolarHBondContact O-N 2.95Å; E193-S196 VanDerWaalsContact O-N 3.14Å; E193-I197 PolarHBondContact O-N 3.22Å; E193-P365 HydrophobicContact CB-CB 4.25Å; E193-P365 HydrophobicContact CB-CG 3.73Å; E193-P365 HydrophobicContact CG-CB 3.72Å; E193-P365 HydrophobicContact CG-CG 3.71Å; E193-S367 WeakPolarHBondContact OE1-CB 3.44Å; E193-S367 PolarHBondContact OE1-OG 3.19Å; E193-S367 PolarHBondContact OE2-OG 3.01Å; E193-M368 HydrophobicContact CB-CG 4.49Å; E193-M368 HydrophobicContact CB-SD 3.71Å
194	V	86.4	Confident	85.6	Confident	0 Å²	0	50.5 Å²	50.5	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-61.9	-42.7	177.2	170.9	0	0	0	0	111.8	M149 I152 L153 K190 V191 S196 I197 V198 M368	M149-V194 HydrophobicContact CB-CG2 4.11Å; M149-V194 HydrophobicContact CG-CG1 4.02Å; M149-V194 HydrophobicContact CG-CG2 4.12Å; I152-V194 HydrophobicContact CB-CG2 4.43Å; I152-V194 HydrophobicContact CD1-CG2 3.83Å; I152-V194 HydrophobicContact CG2-CB 4.43Å; I152-V194 HydrophobicContact CG2-CG1 4.28Å; I152-V194 HydrophobicContact CG2-CG2 4.44Å; L153-V194 HydrophobicContact CD2-CG1 4.25Å; L153-V194 HydrophobicContact CG-CG1 4.32Å; K190-V194 WeakPolarHBondContact O-CG2 3.15Å; K190-V194 PolarHBondContact O-N 3.3Å; V191-V194 PolarHBondContact O-N 3.45Å; V194-S196 PolarHBondContact O-N 3.01Å; V194-I197 PolarHBondContact O-N 2.97Å; V194-I197 VanDerWaalsContact O-N 3.17Å; V194-V198 HydrophobicContact CG1-CG2 4.32Å; V194-V198 WeakPolarHBondContact O-CG2 3.42Å; V194-V198 PolarHBondContact O-N 3.27Å; V194-M368 HydrophobicContact CG2-CE 4.09Å
195	K	85.5	Confident	86.3	Confident	16 Å²	16	55.7 Å²	55.7	7%	0.07	28%	0.275	C	S	.	.	H	α-helix	trans	-59.3	-36.7	175.9	-77.6	176.9	-178.3	-179.1	0	112.4	T173 L175 D176 V191 E192 E193 I197 V198 K199	T173-K195 WeakPolarHBondContact OG1-CE 3.14Å; T173-K195 PolarHBondContact OG1-NZ 3.39Å; L175-K195 HydrophobicContact CB-CD 4.35Å; L175-K195 HydrophobicContact CB-CG 3.83Å; L175-K195 HydrophobicContact CD1-CG 3.63Å; L175-K195 HydrophobicContact CG-CG 4.37Å; D176-K195 IonicContact OD1-NZ 3.26Å; D176-K195 PolarHBondContact OD1-NZ 3.37Å; D176-K195 IonicContact OD2-NZ 3.44Å; D176-K195 PolarHBondContact OD2-NZ 2.92Å; V191-K195 WeakPolarHBondContact O-CG 3.16Å; V191-K195 PolarHBondContact O-N 3.01Å; E192-K195 PolarHBondContact O-N 3.47Å; E192-K195 IonicContact OE1-NZ 3.9Å; E192-K195 PolarHBondContact OE1-NZ 2.9Å; E193-K195 PolarHBondContact O-N 3.42Å; K195-I197 VanDerWaalsContact C-N 3.34Å; K195-V198 PolarHBondContact O-N 3.42Å; K195-K199 VanDerWaalsContact O-CG 3.3Å; K195-K199 WeakPolarHBondContact O-CG 3.4Å; K195-K199 PolarHBondContact O-N 3.4Å; K195-K199 VanDerWaalsContact O-N 3.09Å
196	S	83.7	Confident	86.7	Confident	37 Å²	37	49.1 Å²	49.1	26%	0.259	25%	0.251	S	S	.	.	H	α-helix	trans	-64.6	-41.5	178.6	-58.5	0	0	0	0	110.7	E192 E193 V194 K199 I200	E192-S196 PolarHBondContact O-N 3.14Å; E192-S196 PolarHBondContact O-OG 3.2Å; E193-S196 WeakPolarHBondContact O-CB 3.3Å; E193-S196 PolarHBondContact O-N 2.95Å; E193-S196 VanDerWaalsContact O-N 3.14Å; V194-S196 PolarHBondContact O-N 3.01Å; S196-K199 PolarHBondContact O-N 3.42Å; S196-I200 WeakPolarHBondContact O-CD1 3.3Å; S196-I200 WeakPolarHBondContact O-CG1 3.36Å; S196-I200 PolarHBondContact O-N 2.89Å
197	I	86.1	Confident	87.1	Confident	0 Å²	0	47.5 Å²	47.5	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-64.2	-46.9	173.6	-63.7	-178.1	0	0	0	111.7	M149 E193 V194 K195 K199 I200 L201 M368 I372 L375	M149-I197 HydrophobicContact SD-CD1 4.5Å; M149-I197 HydrophobicContact SD-CG2 4.23Å; E193-I197 PolarHBondContact O-N 3.22Å; V194-I197 PolarHBondContact O-N 2.97Å; V194-I197 VanDerWaalsContact O-N 3.17Å; K195-I197 VanDerWaalsContact C-N 3.34Å; I197-K199 PolarHBondContact O-N 2.95Å; I197-I200 WeakPolarHBondContact O-CA 3.2Å; I197-I200 WeakPolarHBondContact O-CB 3.42Å; I197-I200 PolarHBondContact O-N 3.36Å; I197-L201 PolarHBondContact O-N 2.98Å; I197-L201 VanDerWaalsContact O-N 3.14Å; I197-M368 HydrophobicContact CD1-CB 3.9Å; I197-M368 HydrophobicContact CD1-CE 4.31Å; I197-M368 HydrophobicContact CD1-CG 4.3Å; I197-M368 HydrophobicContact CD1-SD 3.39Å; I197-M368 WeakPolarHBondContact CD1-SD 3.26Å; I197-M368 HydrophobicContact CG1-SD 4.32Å; I197-I372 HydrophobicContact CG1-CD1 4.4Å; I197-I372 HydrophobicContact CG2-CD1 4.1Å; I197-L375 HydrophobicContact CG2-CD1 3.76Å
198	V	86.1	Confident	87.6	Confident	51 Å²	51	45.6 Å²	45.6	31%	0.309	23%	0.23	S	C	.	.	H	α-helix	trans	-58.6	-34	-179.9	172.7	0	0	0	0	111.6	L153 L175 V194 K195 I200 P202	L153-V198 HydrophobicContact CD2-CG2 4.21Å; L175-V198 HydrophobicContact CD1-CB 4.5Å; L175-V198 HydrophobicContact CD1-CG2 4.26Å; V194-V198 HydrophobicContact CG1-CG2 4.32Å; V194-V198 WeakPolarHBondContact O-CG2 3.42Å; V194-V198 PolarHBondContact O-N 3.27Å; K195-V198 PolarHBondContact O-N 3.42Å; V198-I200 VanDerWaalsContact C-N 3.28Å; V198-I200 PolarHBondContact O-N 3.49Å; V198-P202 WeakPolarHBondContact O-CD 3.43Å
199	K	84.5	Confident	88.2	Confident	151 Å²	151	42.9 Å²	42.9	66%	0.657	22%	0.219	S	C	*	.	H	α-helix	trans	-68.9	-22.7	174.8	-72.2	170	-176.5	171.6	0	113.7	K195 S196 I197	K195-K199 VanDerWaalsContact O-CG 3.3Å; K195-K199 WeakPolarHBondContact O-CG 3.4Å; K195-K199 PolarHBondContact O-N 3.4Å; K195-K199 VanDerWaalsContact O-N 3.09Å; S196-K199 PolarHBondContact O-N 3.42Å; I197-K199 PolarHBondContact O-N 2.95Å
200	I	86.1	Confident	88.8	Confident	6 Å²	6	36 Å²	36	3%	0.031	19%	0.187	C	C	.	.	H	α-helix	trans	-87.6	-30.4	179.6	-61.7	161.7	0	0	0	111.1	S196 I197 V198 P202 V203 F204 F359 A363 I372	S196-I200 WeakPolarHBondContact O-CD1 3.3Å; S196-I200 WeakPolarHBondContact O-CG1 3.36Å; S196-I200 PolarHBondContact O-N 2.89Å; I197-I200 WeakPolarHBondContact O-CA 3.2Å; I197-I200 WeakPolarHBondContact O-CB 3.42Å; I197-I200 PolarHBondContact O-N 3.36Å; V198-I200 VanDerWaalsContact C-N 3.28Å; V198-I200 PolarHBondContact O-N 3.49Å; I200-P202 VanDerWaalsContact C-N 3.32Å; I200-P202 VanDerWaalsContact O-N 3.14Å; I200-V203 WeakPolarHBondContact O-CB 3.32Å; I200-V203 PolarHBondContact O-N 3.03Å; I200-F204 HydrophobicContact CG2-CD1 4.25Å; I200-F204 HydrophobicContact CG2-CE1 3.64Å; I200-F204 HydrophobicContact CG2-CE2 4.12Å; I200-F204 HydrophobicContact CG2-CZ 3.57Å; I200-F359 HydrophobicContact CG2-CE1 4.09Å; I200-A363 HydrophobicContact CD1-CB 3.44Å; I200-A363 VanDerWaalsContact CD1-CB 3.44Å; I200-A363 HydrophobicContact CG1-CB 3.88Å; I200-I372 HydrophobicContact CB-CD1 4.48Å; I200-I372 HydrophobicContact CD1-CD1 4.17Å; I200-I372 HydrophobicContact CG2-CD1 4.2Å
201	L	89	Confident	89.4	Confident	45 Å²	45	33.5 Å²	33.5	24%	0.236	18%	0.176	C	C	.	.	H	α-helix	trans	-47.6	-42.4	-177.8	-72.5	177.6	0	0	0	114.9	I197 V203 F204 F205 L375 F379	I197-L201 PolarHBondContact O-N 2.98Å; I197-L201 VanDerWaalsContact O-N 3.14Å; L201-V203 PolarHBondContact O-N 3.19Å; L201-F204 HydrophobicContact CD2-CD2 4.21Å; L201-F204 WeakPolarHBondContact O-CA 3.36Å; L201-F204 WeakPolarHBondContact O-CB 3.27Å; L201-F204 PolarHBondContact O-N 3.35Å; L201-F205 HydrophobicContact CB-CD2 4.48Å; L201-F205 HydrophobicContact CB-CE2 4.36Å; L201-F205 VanDerWaalsContact O-CD2 3.24Å; L201-F205 WeakPolarHBondContact O-CD2 3.5Å; L201-F205 PolarHBondContact O-N 2.87Å; L201-L375 HydrophobicContact CD2-CD1 4.45Å; L201-F379 HydrophobicContact CD2-CE2 3.87Å; L201-F379 HydrophobicContact CD2-CZ 4.27Å
202	P	88.9	Confident	89.9	Confident	82 Å²	82	34 Å²	34	53%	0.532	18%	0.178	S	C	.	.	H	α-helix	trans	-56.5	-33.3	177.1	-26.9	36	0	0	0	114	V198 I200 A206	V198-P202 WeakPolarHBondContact O-CD 3.43Å; I200-P202 VanDerWaalsContact C-N 3.32Å; I200-P202 VanDerWaalsContact O-N 3.14Å; P202-A206 WeakPolarHBondContact O-CB 3.39Å; P202-A206 PolarHBondContact O-N 3.48Å; P202-A206 VanDerWaalsContact O-N 3.08Å
203	V	87.8	Confident	90.5	Very high	20 Å²	20	30.7 Å²	30.7	12%	0.121	16%	0.163	C	C	.	.	H	α-helix	trans	-68.1	-37.6	175.7	179.8	0	0	0	0	110.6	I200 L201 A206 L207 L285 I288 F359 F434	I200-V203 WeakPolarHBondContact O-CB 3.32Å; I200-V203 PolarHBondContact O-N 3.03Å; L201-V203 PolarHBondContact O-N 3.19Å; V203-A206 PolarHBondContact O-N 3.42Å; V203-L207 HydrophobicContact CG1-CD1 4.45Å; V203-L207 WeakPolarHBondContact O-CG 3.3Å; V203-L207 PolarHBondContact O-N 3.13Å; V203-L207 VanDerWaalsContact O-N 3.16Å; V203-L285 HydrophobicContact CG1-CD2 4.3Å; V203-L285 HydrophobicContact CG2-CD2 4.14Å; V203-I288 HydrophobicContact CG1-CD1 4.48Å; V203-F359 HydrophobicContact CB-CE1 4.14Å; V203-F359 HydrophobicContact CG1-CD1 4.2Å; V203-F359 HydrophobicContact CG1-CE1 4.04Å; V203-F359 HydrophobicContact CG2-CE1 3.85Å; V203-F359 HydrophobicContact CG2-CZ 4.3Å; V203-F434 HydrophobicContact CG1-CE2 4.25Å
204	F	92.2	Very high	90.8	Very high	2 Å²	2	31.1 Å²	31.1	1%	0.009	16%	0.164	C	C	.	.	H	α-helix	trans	-68.7	-41.3	177.1	-63.3	-12.3	0	0	0	112.4	I200 L201 A206 L207 I208 A360 I372 L375 F376 F379	I200-F204 HydrophobicContact CG2-CD1 4.25Å; I200-F204 HydrophobicContact CG2-CE1 3.64Å; I200-F204 HydrophobicContact CG2-CE2 4.12Å; I200-F204 HydrophobicContact CG2-CZ 3.57Å; L201-F204 HydrophobicContact CD2-CD2 4.21Å; L201-F204 WeakPolarHBondContact O-CA 3.36Å; L201-F204 WeakPolarHBondContact O-CB 3.27Å; L201-F204 PolarHBondContact O-N 3.35Å; F204-A206 VanDerWaalsContact C-N 3.29Å; F204-A206 PolarHBondContact O-N 2.84Å; F204-L207 WeakPolarHBondContact O-CB 3.42Å; F204-L207 PolarHBondContact O-N 3.2Å; F204-L207 VanDerWaalsContact O-N 3.08Å; F204-I208 PolarHBondContact O-N 3.45Å; F204-A360 HydrophobicContact CE1-CB 3.79Å; F204-A360 HydrophobicContact CZ-CB 3.68Å; F204-I372 HydrophobicContact CE2-CD1 3.53Å; F204-I372 HydrophobicContact CE2-CG1 4.08Å; F204-I372 HydrophobicContact CZ-CD1 3.6Å; F204-I372 HydrophobicContact CZ-CG1 3.76Å; F204-L375 HydrophobicContact CD2-CB 4.31Å; F204-L375 HydrophobicContact CE2-CB 3.94Å; F204-F376 HydrophobicContact CD1-CD2 4.38Å; F204-F376 AromaticContact CE1-CD2 3.99Å; F204-F376 HydrophobicContact CE1-CD2 3.99Å; F204-F376 HydrophobicContact CZ-CB 4.44Å; F204-F376 HydrophobicContact CZ-CD2 4.48Å; F204-F379 HydrophobicContact CB-CB 4.2Å; F204-F379 HydrophobicContact CB-CD1 4.22Å; F204-F379 HydrophobicContact CB-CD2 3.61Å; F204-F379 HydrophobicContact CB-CE2 4.01Å; F204-F379 HydrophobicContact CB-CG 3.74Å; F204-F379 HydrophobicContact CB-CZ 4.46Å; F204-F379 AromaticContact CD2-CD2 3.81Å; F204-F379 HydrophobicContact CD2-CD2 3.81Å; F204-F379 HydrophobicContact CD2-CE2 4.09Å; F204-F379 HydrophobicContact CG-CD2 4.13Å
205	F	92.7	Very high	91.1	Very high	117 Å²	117	33.4 Å²	33.4	51%	0.513	17%	0.173	S	C	.	.	H	α-helix	trans	-59.7	-41.7	172.4	-78.8	-76.7	0	0	0	111.7	L201 L207 I208 F379	L201-F205 HydrophobicContact CB-CD2 4.48Å; L201-F205 HydrophobicContact CB-CE2 4.36Å; L201-F205 VanDerWaalsContact O-CD2 3.24Å; L201-F205 WeakPolarHBondContact O-CD2 3.5Å; L201-F205 PolarHBondContact O-N 2.87Å; F205-L207 PolarHBondContact O-N 2.83Å; F205-I208 HydrophobicContact CD1-CD1 3.79Å; F205-I208 HydrophobicContact CE1-CD1 4.5Å; F205-I208 WeakPolarHBondContact O-CB 3.47Å; F205-I208 WeakPolarHBondContact O-CG1 3.5Å; F205-I208 PolarHBondContact O-N 2.97Å; F205-I208 VanDerWaalsContact O-N 3.16Å; F205-F379 AromaticContact CD1-CE1 3.71Å; F205-F379 HydrophobicContact CD1-CE1 3.71Å; F205-F379 HydrophobicContact CD1-CZ 4.46Å; F205-F379 HydrophobicContact CD2-CE1 4.1Å; F205-F379 HydrophobicContact CD2-CZ 4.16Å; F205-F379 AromaticContact CE1-CE1 3.56Å; F205-F379 HydrophobicContact CE1-CE1 3.56Å; F205-F379 HydrophobicContact CE1-CZ 4.07Å; F205-F379 AromaticContact CE2-CE1 3.94Å; F205-F379 HydrophobicContact CE2-CE1 3.94Å; F205-F379 AromaticContact CE2-CZ 3.72Å; F205-F379 HydrophobicContact CE2-CZ 3.72Å; F205-F379 AromaticContact CG-CE1 3.97Å; F205-F379 HydrophobicContact CG-CE1 3.97Å; F205-F379 HydrophobicContact CG-CZ 4.49Å; F205-F379 AromaticContact CZ-CE1 3.67Å; F205-F379 HydrophobicContact CZ-CE1 3.67Å; F205-F379 AromaticContact CZ-CZ 3.67Å; F205-F379 HydrophobicContact CZ-CZ 3.67Å
206	A	91.9	Very high	91.3	Very high	25 Å²	25	32.7 Å²	32.7	21%	0.207	17%	0.171	C	C	.	.	H	α-helix	trans	-67.1	-18.6	176.8	0	0	0	0	0	113.8	P202 V203 F204 M292 T430 F434	P202-A206 WeakPolarHBondContact O-CB 3.39Å; P202-A206 PolarHBondContact O-N 3.48Å; P202-A206 VanDerWaalsContact O-N 3.08Å; V203-A206 PolarHBondContact O-N 3.42Å; F204-A206 VanDerWaalsContact C-N 3.29Å; F204-A206 PolarHBondContact O-N 2.84Å; A206-M292 VanDerWaalsContact O-CE 3.28Å; A206-M292 WeakPolarHBondContact O-CE 3.36Å; A206-T430 VanDerWaalsContact O-CG2 3.3Å; A206-T430 WeakPolarHBondContact O-CG2 3.4Å; A206-F434 HydrophobicContact CB-CD2 3.64Å; A206-F434 HydrophobicContact CB-CE2 4.09Å
207	L	94.2	Very high	91.5	Very high	2 Å²	2	31.2 Å²	31.2	1%	0.01	16%	0.16	C	C	.	.	H	α-helix	trans	-85.9	-9.9	174.9	-74.8	168.5	0	0	0	113.4	V203 F204 F205 Y210 W211 I288 M292 F376	V203-L207 HydrophobicContact CG1-CD1 4.45Å; V203-L207 WeakPolarHBondContact O-CG 3.3Å; V203-L207 PolarHBondContact O-N 3.13Å; V203-L207 VanDerWaalsContact O-N 3.16Å; F204-L207 WeakPolarHBondContact O-CB 3.42Å; F204-L207 PolarHBondContact O-N 3.2Å; F204-L207 VanDerWaalsContact O-N 3.08Å; F205-L207 PolarHBondContact O-N 2.83Å; L207-Y210 HydrophobicContact CD2-CD1 4.1Å; L207-Y210 HydrophobicContact CD2-CG 4.24Å; L207-Y210 WeakPolarHBondContact O-CB 3.2Å; L207-Y210 PolarHBondContact O-N 3.46Å; L207-Y210 VanDerWaalsContact O-N 3.14Å; L207-W211 PolarHBondContact O-N 3.28Å; L207-I288 HydrophobicContact CD2-CG2 3.79Å; L207-M292 HydrophobicContact CD2-CE 3.65Å; L207-M292 HydrophobicContact CG-CE 4.24Å; L207-F376 HydrophobicContact CD1-CE2 4.18Å
208	I	96.3	Very high	91.5	Very high	26 Å²	26	36.1 Å²	36.1	13%	0.133	18%	0.182	C	C	.	.	H	α-helix	trans	-56.5	-48.4	179.1	-65.9	170.8	0	0	0	111.5	F204 F205 Y210 W211 M212 F379 I382	F204-I208 PolarHBondContact O-N 3.45Å; F205-I208 HydrophobicContact CD1-CD1 3.79Å; F205-I208 HydrophobicContact CE1-CD1 4.5Å; F205-I208 WeakPolarHBondContact O-CB 3.47Å; F205-I208 WeakPolarHBondContact O-CG1 3.5Å; F205-I208 PolarHBondContact O-N 2.97Å; F205-I208 VanDerWaalsContact O-N 3.16Å; I208-Y210 VanDerWaalsContact C-N 3.3Å; I208-Y210 PolarHBondContact O-N 3.07Å; I208-W211 PolarHBondContact O-N 2.87Å; I208-M212 PolarHBondContact O-N 3.47Å; I208-F379 HydrophobicContact CD1-CD1 3.88Å; I208-F379 HydrophobicContact CD1-CE1 4.2Å; I208-F379 HydrophobicContact CG1-CD1 3.97Å; I208-I382 HydrophobicContact CD1-CG2 4.06Å; I208-I382 HydrophobicContact CG1-CG2 4.37Å; I208-I382 HydrophobicContact CG2-CG2 4.25Å
209	P	96.6	Very high	91.6	Very high	19 Å²	19	36 Å²	36	12%	0.123	18%	0.182	C	C	.	.	H	α-helix	trans	-63.4	-35.4	176.7	-26.7	40.2	0	0	0	113.3	W211 M212 V213 I426 Q427 T430	P209-W211 PolarHBondContact O-N 3.04Å; P209-M212 VanDerWaalsContact O-CB 3.27Å; P209-M212 WeakPolarHBondContact O-CB 3.42Å; P209-M212 PolarHBondContact O-N 2.9Å; P209-V213 WeakPolarHBondContact O-CG2 3.43Å; P209-V213 PolarHBondContact O-N 2.84Å; P209-V213 VanDerWaalsContact O-N 3.12Å; P209-I426 HydrophobicContact CB-CG2 4.1Å; P209-Q427 PolarHBondContact O-OE1 2.86Å; P209-T430 HydrophobicContact CB-CG2 4.05Å; P209-T430 WeakPolarHBondContact CB-OG1 3.34Å; P209-T430 HydrophobicContact CG-CG2 3.82Å; P209-T430 VanDerWaalsContact CG-OG1 3.3Å; P209-T430 WeakPolarHBondContact CG-OG1 3.5Å
210	Y	96.9	Very high	91.8	Very high	0 Å²	0	29 Å²	29	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-59	-48.9	174.9	164	-95.4	0	0	0	111.1	L207 I208 M212 V213 Y214 V295 S348 E349 A352 Q427	L207-Y210 HydrophobicContact CD2-CD1 4.1Å; L207-Y210 HydrophobicContact CD2-CG 4.24Å; L207-Y210 WeakPolarHBondContact O-CB 3.2Å; L207-Y210 PolarHBondContact O-N 3.46Å; L207-Y210 VanDerWaalsContact O-N 3.14Å; I208-Y210 VanDerWaalsContact C-N 3.3Å; I208-Y210 PolarHBondContact O-N 3.07Å; Y210-M212 VanDerWaalsContact C-N 3.31Å; Y210-M212 PolarHBondContact O-N 3.41Å; Y210-V213 PolarHBondContact O-N 2.83Å; Y210-Y214 WeakPolarHBondContact O-CB 3.43Å; Y210-Y214 PolarHBondContact O-N 3.26Å; Y210-V295 HydrophobicContact CD2-CB 4.17Å; Y210-V295 HydrophobicContact CD2-CG1 3.79Å; Y210-V295 HydrophobicContact CE2-CB 4.15Å; Y210-V295 HydrophobicContact CE2-CG1 4.29Å; Y210-V295 HydrophobicContact CE2-CG2 4.36Å; Y210-S348 WeakPolarHBondContact CE2-OG 3.42Å; Y210-E349 WeakPolarHBondContact OH-CA 3.3Å; Y210-A352 HydrophobicContact CD1-CB 4.46Å; Y210-A352 HydrophobicContact CD2-CB 3.82Å; Y210-A352 HydrophobicContact CE1-CB 4.06Å; Y210-A352 HydrophobicContact CE2-CB 3.4Å; Y210-A352 HydrophobicContact CG-CB 4.34Å; Y210-Q427 VanDerWaalsContact N-OE1 3.13Å
211	W	96.5	Very high	92	Very high	15 Å²	15	28.7 Å²	28.7	6%	0.057	15%	0.15	C	C	.	.	H	α-helix	trans	-65.4	-34.7	178.1	-70.9	119.8	0	0	0	113	L207 I208 P209 V213 Y214 F215 S353 F376 S380	L207-W211 PolarHBondContact O-N 3.28Å; I208-W211 PolarHBondContact O-N 2.87Å; P209-W211 PolarHBondContact O-N 3.04Å; W211-V213 PolarHBondContact O-N 2.91Å; W211-Y214 AromaticContact CE3-CD1 3.78Å; W211-Y214 HydrophobicContact CE3-CD1 3.78Å; W211-Y214 HydrophobicContact CE3-CE1 4.41Å; W211-Y214 HydrophobicContact CE3-CG 4.28Å; W211-Y214 AromaticContact CZ3-CD1 3.77Å; W211-Y214 HydrophobicContact CZ3-CD1 3.77Å; W211-Y214 AromaticContact CZ3-CE1 3.98Å; W211-Y214 HydrophobicContact CZ3-CE1 3.98Å; W211-Y214 HydrophobicContact CZ3-CG 4.37Å; W211-Y214 PolarHBondContact O-N 3.45Å; W211-F215 VanDerWaalsContact O-CB 3.29Å; W211-F215 WeakPolarHBondContact O-CB 3.45Å; W211-F215 PolarHBondContact O-N 3.31Å; W211-S353 WeakPolarHBondContact CH2-OG 3.39Å; W211-F376 HydrophobicContact CH2-CE1 4.29Å; W211-F376 HydrophobicContact CH2-CZ 4.43Å; W211-F376 AromaticContact CZ2-CE1 3.65Å; W211-F376 HydrophobicContact CZ2-CE1 3.65Å; W211-F376 HydrophobicContact CZ2-CE2 4.45Å; W211-F376 AromaticContact CZ2-CZ 3.58Å; W211-F376 HydrophobicContact CZ2-CZ 3.58Å; W211-S380 VanDerWaalsContact CD2-OG 3.28Å; W211-S380 VanDerWaalsContact CE3-OG 3.27Å
212	M	95.5	Very high	91.9	Very high	11 Å²	11	28 Å²	28	5%	0.054	15%	0.146	C	C	.	.	H	α-helix	trans	-56.9	-46.7	174	-172.1	-168	-52.4	0	0	112.2	I208 P209 Y210 Q216 G383 V386 L390 L423	I208-M212 PolarHBondContact O-N 3.47Å; P209-M212 VanDerWaalsContact O-CB 3.27Å; P209-M212 WeakPolarHBondContact O-CB 3.42Å; P209-M212 PolarHBondContact O-N 2.9Å; Y210-M212 VanDerWaalsContact C-N 3.31Å; Y210-M212 PolarHBondContact O-N 3.41Å; M212-Q216 PolarHBondContact O-NE2 2.99Å; M212-G383 WeakPolarHBondContact CA-O 3.3Å; M212-V386 HydrophobicContact CE-CB 4.12Å; M212-V386 HydrophobicContact CE-CG1 3.39Å; M212-V386 HydrophobicContact SD-CG1 4.5Å; M212-L390 HydrophobicContact SD-CD2 4Å; M212-L423 HydrophobicContact CG-CD2 4.05Å; M212-L423 HydrophobicContact SD-CD2 3.75Å
213	V	96.4	Very high	91.8	Very high	1 Å²	1	26 Å²	26	1%	0.006	13%	0.131	C	C	.	.	H	α-helix	trans	-76	-43.3	179.2	-173.3	0	0	0	0	111.2	P209 Y210 W211 F215 Q216 V295 A299 L423 Q427	P209-V213 WeakPolarHBondContact O-CG2 3.43Å; P209-V213 PolarHBondContact O-N 2.84Å; P209-V213 VanDerWaalsContact O-N 3.12Å; Y210-V213 PolarHBondContact O-N 2.83Å; W211-V213 PolarHBondContact O-N 2.91Å; V213-F215 VanDerWaalsContact C-N 3.28Å; V213-F215 PolarHBondContact O-N 3.46Å; V213-Q216 VanDerWaalsContact O-CB 3.23Å; V213-Q216 WeakPolarHBondContact O-CB 3.44Å; V213-Q216 WeakPolarHBondContact O-CG 3.49Å; V213-Q216 PolarHBondContact O-N 2.89Å; V213-Q216 VanDerWaalsContact O-N 3.08Å; V213-V295 HydrophobicContact CB-CG1 4.34Å; V213-V295 HydrophobicContact CB-CG2 3.94Å; V213-V295 HydrophobicContact CG1-CG1 4.49Å; V213-V295 HydrophobicContact CG1-CG2 3.74Å; V213-A299 HydrophobicContact CG1-CB 3.85Å; V213-L423 HydrophobicContact CG2-CB 4.09Å; V213-L423 HydrophobicContact CG2-CD2 4.39Å; V213-Q427 HydrophobicContact CG2-CB 4.09Å
214	Y	94.4	Very high	92	Very high	28 Å²	28	25.1 Å²	25.1	11%	0.11	13%	0.126	C	C	.	.	H	α-helix	trans	-56.2	-42.9	178.7	174.9	-94	0	0	0	112	Y210 W211 Q216 M217 I345 E349	Y210-Y214 WeakPolarHBondContact O-CB 3.43Å; Y210-Y214 PolarHBondContact O-N 3.26Å; W211-Y214 AromaticContact CE3-CD1 3.78Å; W211-Y214 HydrophobicContact CE3-CD1 3.78Å; W211-Y214 HydrophobicContact CE3-CE1 4.41Å; W211-Y214 HydrophobicContact CE3-CG 4.28Å; W211-Y214 AromaticContact CZ3-CD1 3.77Å; W211-Y214 HydrophobicContact CZ3-CD1 3.77Å; W211-Y214 AromaticContact CZ3-CE1 3.98Å; W211-Y214 HydrophobicContact CZ3-CE1 3.98Å; W211-Y214 HydrophobicContact CZ3-CG 4.37Å; W211-Y214 PolarHBondContact O-N 3.45Å; Y214-Q216 PolarHBondContact O-N 2.71Å; Y214-Q216 VanDerWaalsContact O-N 3.12Å; Y214-M217 HydrophobicContact CE1-CE 4.35Å; Y214-M217 HydrophobicContact CE2-CE 4Å; Y214-M217 WeakPolarHBondContact O-CB 3.26Å; Y214-M217 PolarHBondContact O-N 2.97Å; Y214-I345 HydrophobicContact CD2-CG2 3.97Å; Y214-I345 HydrophobicContact CE2-CG2 3.92Å; Y214-E349 HydrophobicContact CE2-CB 4.11Å; Y214-E349 HydrophobicContact CE2-CG 4.15Å; Y214-E349 WeakPolarHBondContact CE2-OE2 3Å; Y214-E349 VanDerWaalsContact CZ-OE2 3.25Å; Y214-E349 VanDerWaalsContact OH-CD 3.29Å; Y214-E349 PolarHBondContact OH-OE2 2.97Å
215	F	91.3	Very high	91.8	Very high	47 Å²	47	25 Å²	25	21%	0.206	13%	0.125	C	C	.	.	G	3₁₀ helix	trans	-64.5	-17.7	-179.2	-169.4	-106.7	0	0	0	113.9	W211 V213 M217 Q218 T219 S384	W211-F215 VanDerWaalsContact O-CB 3.29Å; W211-F215 WeakPolarHBondContact O-CB 3.45Å; W211-F215 PolarHBondContact O-N 3.31Å; V213-F215 VanDerWaalsContact C-N 3.28Å; V213-F215 PolarHBondContact O-N 3.46Å; F215-M217 PolarHBondContact O-N 3.15Å; F215-Q218 PolarHBondContact O-N 3.27Å; F215-T219 HydrophobicContact CD1-CG2 4.27Å; F215-T219 HydrophobicContact CE1-CG2 3.73Å; F215-T219 HydrophobicContact CZ-CG2 4.3Å; F215-T219 PolarHBondContact O-OG1 3.28Å; F215-S384 WeakPolarHBondContact CD2-OG 3.43Å; F215-S384 VanDerWaalsContact CG-OG 3.3Å; F215-S384 WeakPolarHBondContact CG-OG 3.41Å
216	Q	91.3	Very high	91.4	Very high	2 Å²	2	21.6 Å²	21.6	1%	0.009	11%	0.11	C	C	.	.	G	3₁₀ helix	trans	-62.5	-26.6	176.8	-60.7	-47.3	-48.8	0	0	113.4	M212 V213 Y214 Q218 T219 T220 Y221 Y419 L423	M212-Q216 PolarHBondContact O-NE2 2.99Å; V213-Q216 VanDerWaalsContact O-CB 3.23Å; V213-Q216 WeakPolarHBondContact O-CB 3.44Å; V213-Q216 WeakPolarHBondContact O-CG 3.49Å; V213-Q216 PolarHBondContact O-N 2.89Å; V213-Q216 VanDerWaalsContact O-N 3.08Å; Y214-Q216 PolarHBondContact O-N 2.71Å; Y214-Q216 VanDerWaalsContact O-N 3.12Å; Q216-Q218 PolarHBondContact O-N 3.32Å; Q216-T219 CarbonylContact O-C 3.55Å; Q216-T219 PolarHBondContact O-N 3.49Å; Q216-T219 PolarHBondContact OE1-OG1 3.26Å; Q216-T220 WeakPolarHBondContact CB-OG1 3.5Å; Q216-T220 PolarHBondContact O-N 2.8Å; Q216-T220 PolarHBondContact OE1-OG1 3.46Å; Q216-Y221 HydrophobicContact CB-CD1 4.03Å; Q216-Y221 HydrophobicContact CB-CE1 3.96Å; Q216-Y221 WeakPolarHBondContact O-CB 3.37Å; Q216-Y221 PolarHBondContact O-N 3.07Å; Q216-Y419 PolarHBondContact NE2-OH 2.98Å; Q216-Y419 VanDerWaalsContact NE2-OH 3.15Å; Q216-Y419 PolarHBondContact OE1-OH 2.88Å; Q216-L423 HydrophobicContact CG-CD1 3.52Å
217	M	87.8	Confident	91.2	Very high	6 Å²	6	20.4 Å²	20.4	3%	0.03	10%	0.1	C	C	.	.	G	3₁₀ helix	trans	-53.3	-35.3	172.4	-177	-177.9	46.1	0	0	112.5	Y214 F215 Y221 I222 D256 Y342 I345	Y214-M217 HydrophobicContact CE1-CE 4.35Å; Y214-M217 HydrophobicContact CE2-CE 4Å; Y214-M217 WeakPolarHBondContact O-CB 3.26Å; Y214-M217 PolarHBondContact O-N 2.97Å; F215-M217 PolarHBondContact O-N 3.15Å; M217-Y221 HydrophobicContact CB-CD2 4.45Å; M217-I222 WeakPolarHBondContact O-CG1 3.18Å; M217-D256 HydrophobicContact SD-CB 3.7Å; M217-D256 VanDerWaalsContact SD-CG 3.58Å; M217-Y342 HydrophobicContact CG-CD1 3.94Å; M217-Y342 HydrophobicContact CG-CE1 3.41Å; M217-Y342 VanDerWaalsContact CG-CE1 3.41Å; M217-Y342 HydrophobicContact SD-CD1 4.03Å; M217-Y342 HydrophobicContact SD-CE1 4Å; M217-I345 HydrophobicContact CB-CD1 3.9Å; M217-I345 HydrophobicContact CE-CG2 4.18Å; M217-I345 HydrophobicContact SD-CG2 3.77Å
218	Q	85.3	Confident	91	Very high	102 Å²	102	20.3 Å²	20.3	48%	0.477	10%	0.1	S	C	.	.	G	3₁₀ helix	trans	-88.7	-4.8	-178.2	-62.2	-178.2	8.1	0	0	113.2	F215 Q216	F215-Q218 PolarHBondContact O-N 3.27Å; Q216-Q218 PolarHBondContact O-N 3.32Å
219	T	87.3	Confident	90.6	Very high	50 Å²	50	25 Å²	25	31%	0.307	12%	0.116	S	C	.	.	T	Hydrogen-bonded Turn	trans	-132.5	-92.7	-171.1	54.9	0	0	0	0	111.4	F215 Q216 Y221 I222 L223	F215-T219 HydrophobicContact CD1-CG2 4.27Å; F215-T219 HydrophobicContact CE1-CG2 3.73Å; F215-T219 HydrophobicContact CZ-CG2 4.3Å; F215-T219 PolarHBondContact O-OG1 3.28Å; Q216-T219 CarbonylContact O-C 3.55Å; Q216-T219 PolarHBondContact O-N 3.49Å; Q216-T219 PolarHBondContact OE1-OG1 3.26Å; T219-Y221 VanDerWaalsContact C-N 3.28Å; T219-Y221 PolarHBondContact O-N 3.44Å; T219-I222 WeakPolarHBondContact O-CB 3.01Å; T219-I222 PolarHBondContact O-N 2.99Å; T219-I222 VanDerWaalsContact O-N 3.15Å; T219-L223 PolarHBondContact O-N 3.03Å
220	T	89.6	Confident	90	Very high	2 Å²	2	24.3 Å²	24.3	1%	0.012	11%	0.111	C	C	.	.	H	α-helix	trans	-65.3	-28.6	-172	53.4	0	0	0	0	113.3	Q216 L223 Q224 L391 M402 Y419 F420	Q216-T220 WeakPolarHBondContact CB-OG1 3.5Å; Q216-T220 PolarHBondContact O-N 2.8Å; Q216-T220 PolarHBondContact OE1-OG1 3.46Å; T220-L223 PolarHBondContact O-N 3.33Å; T220-Q224 PolarHBondContact O-N 3.24Å; T220-L391 HydrophobicContact CG2-CD1 3.87Å; T220-L391 HydrophobicContact CG2-CD2 3.9Å; T220-M402 HydrophobicContact CG2-CE 4.11Å; T220-Y419 HydrophobicContact CG2-CD1 4.44Å; T220-Y419 HydrophobicContact CG2-CE1 3.9Å; T220-F420 WeakPolarHBondContact OG1-CE1 3.24Å
221	Y	91.2	Very high	89.1	Confident	1 Å²	1	27.4 Å²	27.4	0%	0.004	13%	0.131	C	C	.	.	H	α-helix	trans	-68	-42	175.3	-76.5	18.5	0	0	0	111.3	Q216 M217 T219 L223 Q224 S225 S298 A302 Q338 Q341 Y342 I345 F420	Q216-Y221 HydrophobicContact CB-CD1 4.03Å; Q216-Y221 HydrophobicContact CB-CE1 3.96Å; Q216-Y221 WeakPolarHBondContact O-CB 3.37Å; Q216-Y221 PolarHBondContact O-N 3.07Å; M217-Y221 HydrophobicContact CB-CD2 4.45Å; T219-Y221 VanDerWaalsContact C-N 3.28Å; T219-Y221 PolarHBondContact O-N 3.44Å; Y221-L223 VanDerWaalsContact C-N 3.32Å; Y221-Q224 WeakPolarHBondContact O-CB 3.01Å; Y221-Q224 PolarHBondContact O-N 3.07Å; Y221-S225 PolarHBondContact O-N 3.47Å; Y221-S225 PolarHBondContact O-OG 3.42Å; Y221-S298 PolarHBondContact OH-O 3.4Å; Y221-S298 PolarHBondContact OH-OG 3.23Å; Y221-A302 HydrophobicContact CD1-CB 4.45Å; Y221-A302 HydrophobicContact CE1-CB 3.66Å; Y221-Q338 PolarHBondContact O-NE2 3.23Å; Y221-Q341 HydrophobicContact CD2-CG 4.24Å; Y221-Q341 HydrophobicContact CE2-CB 4.01Å; Y221-Q341 HydrophobicContact CE2-CG 4.04Å; Y221-Y342 HydrophobicContact CD2-CE2 4.41Å; Y221-I345 HydrophobicContact CD2-CD1 4.01Å; Y221-I345 HydrophobicContact CE2-CD1 3.35Å; Y221-I345 HydrophobicContact CE2-CG1 4.42Å; Y221-F420 AromaticContact CD1-CE1 3.77Å; Y221-F420 HydrophobicContact CD1-CE1 3.77Å; Y221-F420 AromaticContact CD1-CZ 4Å; Y221-F420 HydrophobicContact CD1-CZ 4Å; Y221-F420 HydrophobicContact CE1-CD1 4.08Å; Y221-F420 AromaticContact CE1-CE1 3.62Å; Y221-F420 HydrophobicContact CE1-CE1 3.62Å; Y221-F420 HydrophobicContact CE1-CZ 4.15Å
222	I	87	Confident	87.8	Confident	30 Å²	30	29 Å²	29	15%	0.154	15%	0.152	C	C	.	.	H	α-helix	trans	-64	-40.6	173.5	-64.5	175.5	0	0	0	110.1	M217 T219 Q224 S225 F226 T253	M217-I222 WeakPolarHBondContact O-CG1 3.18Å; T219-I222 WeakPolarHBondContact O-CB 3.01Å; T219-I222 PolarHBondContact O-N 2.99Å; T219-I222 VanDerWaalsContact O-N 3.15Å; I222-Q224 VanDerWaalsContact C-N 3.33Å; I222-Q224 PolarHBondContact O-N 3.06Å; I222-S225 WeakPolarHBondContact O-CA 3.34Å; I222-S225 WeakPolarHBondContact O-CB 3.01Å; I222-S225 PolarHBondContact O-N 3.36Å; I222-F226 HydrophobicContact CG2-CD2 4.22Å; I222-F226 HydrophobicContact CG2-CE1 4.33Å; I222-F226 HydrophobicContact CG2-CE2 3.55Å; I222-F226 HydrophobicContact CG2-CZ 3.61Å; I222-F226 WeakPolarHBondContact O-CD2 3.47Å; I222-F226 PolarHBondContact O-N 3.29Å; I222-F226 VanDerWaalsContact O-N 3.08Å; I222-T253 HydrophobicContact CD1-CG2 3.73Å; I222-T253 HydrophobicContact CG1-CG2 4.43Å
223	L	86.3	Confident	86.4	Confident	41 Å²	41	29.8 Å²	29.8	22%	0.215	16%	0.157	C	C	.	.	H	α-helix	trans	-61.3	-42.4	176.6	-176	64.6	0	0	0	112.2	T219 T220 Y221 S225 F226 H227 M402 I411	T219-L223 PolarHBondContact O-N 3.03Å; T220-L223 PolarHBondContact O-N 3.33Å; Y221-L223 VanDerWaalsContact C-N 3.32Å; L223-S225 VanDerWaalsContact C-N 3.29Å; L223-S225 PolarHBondContact O-N 3.49Å; L223-F226 PolarHBondContact O-N 3.4Å; L223-H227 PolarHBondContact O-ND1 3.02Å; L223-M402 HydrophobicContact CD2-CE 3.2Å; L223-M402 HydrophobicContact CD2-SD 4.38Å; L223-I411 HydrophobicContact CD1-CG2 4.45Å; L223-I411 HydrophobicContact CD2-CG2 3.58Å; L223-I411 HydrophobicContact CG-CG2 3.93Å
224	Q	90.7	Very high	84.9	Confident	0 Å²	0	30.5 Å²	30.5	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-60.3	-40.4	172	177.2	-176.8	64.1	0	0	111.1	T220 Y221 I222 F226 H227 L228 A302 E306 Q338 Q341	T220-Q224 PolarHBondContact O-N 3.24Å; Y221-Q224 WeakPolarHBondContact O-CB 3.01Å; Y221-Q224 PolarHBondContact O-N 3.07Å; I222-Q224 VanDerWaalsContact C-N 3.33Å; I222-Q224 PolarHBondContact O-N 3.06Å; Q224-F226 VanDerWaalsContact C-N 3.29Å; Q224-F226 PolarHBondContact O-N 3.42Å; Q224-H227 PolarHBondContact O-N 2.84Å; Q224-L228 HydrophobicContact CG-CD1 4.43Å; Q224-L228 PolarHBondContact O-N 3.06Å; Q224-A302 PolarHBondContact NE2-O 2.89Å; Q224-E306 WeakPolarHBondContact CG-OE2 3.45Å; Q224-E306 PolarHBondContact NE2-OE2 3.45Å; Q224-Q338 VanDerWaalsContact OE1-NE2 3.09Å; Q224-Q341 VanDerWaalsContact OE1-NE2 3.14Å
225	S	88.1	Confident	83.4	Confident	0 Å²	0	32.8 Å²	32.8	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-59.4	-39	178.4	-49.6	0	0	0	0	112.9	Y221 I222 L223 H227 L228 L252 Q338	Y221-S225 PolarHBondContact O-N 3.47Å; Y221-S225 PolarHBondContact O-OG 3.42Å; I222-S225 WeakPolarHBondContact O-CA 3.34Å; I222-S225 WeakPolarHBondContact O-CB 3.01Å; I222-S225 PolarHBondContact O-N 3.36Å; L223-S225 VanDerWaalsContact C-N 3.29Å; L223-S225 PolarHBondContact O-N 3.49Å; S225-H227 PolarHBondContact O-N 3.26Å; S225-H227 VanDerWaalsContact O-N 3.16Å; S225-L228 PolarHBondContact O-N 2.86Å; S225-L228 VanDerWaalsContact O-N 3.16Å; S225-L252 WeakPolarHBondContact OG-CD1 3.5Å; S225-Q338 VanDerWaalsContact CB-OE1 3.26Å; S225-Q338 PolarHBondContact OG-NE2 2.98Å; S225-Q338 PolarHBondContact OG-OE1 3.14Å
226	F	84.9	Confident	81.9	Confident	46 Å²	46	35.1 Å²	35.1	20%	0.202	20%	0.197	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.7	-12.5	176.8	-64.1	-42	0	0	0	114	I222 L223 Q224 A249 Q321 L323 F328	I222-F226 HydrophobicContact CG2-CD2 4.22Å; I222-F226 HydrophobicContact CG2-CE1 4.33Å; I222-F226 HydrophobicContact CG2-CE2 3.55Å; I222-F226 HydrophobicContact CG2-CZ 3.61Å; I222-F226 WeakPolarHBondContact O-CD2 3.47Å; I222-F226 PolarHBondContact O-N 3.29Å; I222-F226 VanDerWaalsContact O-N 3.08Å; L223-F226 PolarHBondContact O-N 3.4Å; Q224-F226 VanDerWaalsContact C-N 3.29Å; Q224-F226 PolarHBondContact O-N 3.42Å; F226-A249 HydrophobicContact CD1-CB 4.05Å; F226-A249 HydrophobicContact CE1-CB 3.21Å; F226-A249 HydrophobicContact CZ-CB 3.85Å; F226-Q321 PolarHBondContact O-NE2 3.36Å; F226-L323 HydrophobicContact CB-CD1 4.46Å; F226-L323 HydrophobicContact CD1-CD1 3.79Å; F226-L323 HydrophobicContact CE1-CD1 4.49Å; F226-F328 HydrophobicContact CB-CD1 3.98Å; F226-F328 HydrophobicContact CB-CE1 3.99Å; F226-F328 HydrophobicContact CB-CG 4.39Å; F226-F328 HydrophobicContact CB-CZ 4.39Å; F226-F328 HydrophobicContact CD2-CE1 4.36Å; F226-F328 HydrophobicContact CD2-CZ 4.34Å; F226-F328 HydrophobicContact CG-CE1 4.35Å; F226-F328 HydrophobicContact CG-CZ 4.35Å; F226-F328 WeakPolarHBondContact O-CB 3.47Å
227	H	88.6	Confident	80.3	Confident	0 Å²	0	41.1 Å²	41.1	0%	0	23%	0.227	C	C	.	.	T	Hydrogen-bonded Turn	trans	-112	11.5	177.9	-63.7	81.1	0	0	0	112.7	L223 Q224 S225 H329 A330 A331 I411	L223-H227 PolarHBondContact O-ND1 3.02Å; Q224-H227 PolarHBondContact O-N 2.84Å; S225-H227 PolarHBondContact O-N 3.26Å; S225-H227 VanDerWaalsContact O-N 3.16Å; H227-H329 PolarHBondContact CD2-O 3.47Å; H227-A330 WeakPolarHBondContact O-CA 3.5Å; H227-A331 PolarHBondContact O-N 3.35Å; H227-I411 HydrophobicContact CB-CD1 3.9Å; H227-I411 HydrophobicContact CB-CG1 4.1Å
228	L	89.7	Confident	78.7	Confident	0 Å²	0	45.9 Å²	45.9	0%	0	26%	0.261	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-104	155.3	168.1	-65	172.2	0	0	0	109.5	Q224 S225 I230 L305 R309 Q321 L333 I335 Q338	Q224-L228 HydrophobicContact CG-CD1 4.43Å; Q224-L228 PolarHBondContact O-N 3.06Å; S225-L228 PolarHBondContact O-N 2.86Å; S225-L228 VanDerWaalsContact O-N 3.16Å; L228-I230 PolarHBondContact O-N 3.3Å; L228-L305 HydrophobicContact CD1-CD2 4.24Å; L228-R309 HydrophobicContact CD2-CB 4.49Å; L228-R309 HydrophobicContact CD2-CG 3.93Å; L228-Q321 PolarHBondContact O-NE2 3.19Å; L228-Q321 PolarHBondContact O-OE1 3.02Å; L228-L333 HydrophobicContact CD2-CB 3.93Å; L228-L333 HydrophobicContact CD2-CD2 3.76Å; L228-L333 HydrophobicContact CD2-CG 4.04Å; L228-I335 HydrophobicContact CB-CB 4.41Å; L228-Q338 VanDerWaalsContact CD1-CD 3.5Å; L228-Q338 HydrophobicContact CD1-CG 3.46Å; L228-Q338 VanDerWaalsContact CD1-CG 3.46Å
229	R	87.9	Confident	77.2	Confident	125 Å²	125	44.3 Å²	44.3	47%	0.472	26%	0.259	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-68.9	115.8	177.4	-178.6	172.3	176.8	-179	1.4	110.1	A331 D332 L333 I335	R229-A331 PolarHBondContact N-O 3.23Å; R229-D332 WeakPolarHBondContact CD-OD1 3.46Å; R229-D332 IonicContact CZ-OD1 2.84Å; R229-D332 IonicContact NE-OD1 2.72Å; R229-D332 IonicContact NH1-OD1 3.81Å; R229-D332 PolarHBondContact NH1-OD1 3.47Å; R229-D332 IonicContact NH1-OD2 2.83Å; R229-L333 PolarHBondContact N-O 3.02Å; R229-I335 PolarHBondContact O-N 2.9Å
230	I	83.4	Confident	75.2	Confident	4 Å²	4	48.4 Å²	48.4	2%	0.021	28%	0.279	C	S	.	.			trans	-91.3	126.8	173.5	-57.4	-179.6	0	0	0	108.2	L228 G232 T233 F247 L323 I335	L228-I230 PolarHBondContact O-N 3.3Å; I230-G232 PolarHBondContact O-N 2.92Å; I230-T233 HydrophobicContact CB-CG2 4.47Å; I230-T233 PolarHBondContact O-OG1 3.45Å; I230-F247 HydrophobicContact CG2-CB 3.75Å; I230-F247 HydrophobicContact CG2-CD1 4.21Å; I230-F247 HydrophobicContact CG2-CG 4.36Å; I230-L323 HydrophobicContact CD1-CD1 4.15Å; I230-L323 HydrophobicContact CD1-CD2 3.96Å; I230-I335 HydrophobicContact CD1-CD1 4.36Å; I230-I335 HydrophobicContact CG1-CD1 4.01Å
231	P	77.4	Confident	73.4	Confident	65 Å²	65	52.7 Å²	52.7	42%	0.422	31%	0.305	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.1	132.1	174.7	-22.7	33.5	0	0	0	111.3	W336	P231-W336 HydrophobicContact CG-CZ2 4.47Å
232	G	69.6	Low	71.4	Confident	47 Å²	47	57.1 Å²	57.1	49%	0.485	33%	0.332	S	S	.	.	T	Hydrogen-bonded Turn	trans	86.3	5.2	173.1	0	0	0	0	0	116.1	I230	I230-G232 PolarHBondContact O-N 2.92Å
233	T	66.6	Low	69.6	Low	28 Å²	28	64.3 Å²	64.3	17%	0.172	37%	0.365	C	S	.	.			trans	-81.4	132.7	170.1	25.2	0	0	0	0	111.4	I230 T246 Q321 V322 L323	I230-T233 HydrophobicContact CB-CG2 4.47Å; I230-T233 PolarHBondContact O-OG1 3.45Å; T233-T246 HydrophobicContact CG2-CG2 4.44Å; T233-Q321 PolarHBondContact OG1-OE1 3.03Å; T233-V322 WeakPolarHBondContact CG2-O 3.33Å; T233-L323 HydrophobicContact CG2-CD2 4.31Å; T233-L323 HydrophobicContact CG2-CG 4.49Å
234	P	65.1	Low	68.1	Low	17 Å²	17	67.7 Å²	67.7	11%	0.11	38%	0.379	C	S	.	.			trans	-72.4	148.3	176.2	29.6	-33.2	0	0	0	111	T241 V322	P234-T241 HydrophobicContact CG-CG2 4.43Å; P234-V322 PolarHBondContact O-N 3.42Å
235	S	61.6	Low	66.7	Low	75 Å²	75	73.5 Å²	73.5	52%	0.524	41%	0.405	S	S	.	.	S	Bend	trans	-82.5	-21.5	174.1	48.6	0	0	0	0	113.3
236	N	60.8	Low	65.6	Low	96 Å²	96	74.8 Å²	74.8	51%	0.513	41%	0.413	S	S	.	.			trans	-122.6	136.8	-176.9	-73.2	-5.7	0	0	0	112	S238 V239	N236-S238 PolarHBondContact O-N 3.35Å; N236-V239 HydrophobicContact CB-CG2 4.38Å
237	I	57.6	Low	64.9	Low	128 Å²	128	74.5 Å²	74.5	66%	0.656	41%	0.412	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.8	-20.5	179.3	-61.6	171.3	0	0	0	112.3	V322 V327	I237-V322 HydrophobicContact CG1-CG1 4.26Å; I237-V322 HydrophobicContact CG1-CG2 3.82Å; I237-V327 HydrophobicContact CD1-CG2 3.91Å; I237-V327 HydrophobicContact CG1-CG2 4.48Å
238	S	53.9	Low	64	Low	106 Å²	106	74.6 Å²	74.6	74%	0.741	41%	0.412	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.1	-0.5	-174.5	63	0	0	0	0	115.2	N236 D240	N236-S238 PolarHBondContact O-N 3.35Å; S238-D240 PolarHBondContact O-N 3.08Å
239	V	53.8	Low	62.9	Low	70 Å²	70	74.7 Å²	74.7	42%	0.424	41%	0.413	S	S	.	.	S	Bend	trans	-82.3	115.8	176.3	-176.5	0	0	0	0	107.8	N236 T241	N236-V239 HydrophobicContact CB-CG2 4.38Å; V239-T241 PolarHBondContact O-N 3.16Å
240	D	44.8	Very low	61.9	Low	135 Å²	135	69.6 Å²	69.6	72%	0.722	40%	0.398	S	S	*	.			trans	-57.1	108	177.9	-158.2	6.1	0	0	0	109.7	S238 T242	S238-D240 PolarHBondContact O-N 3.08Å; D240-T242 PolarHBondContact O-N 3.26Å; D240-T242 VanDerWaalsContact O-N 3.15Å
241	T	51.7	Low	61.6	Low	92 Å²	92	71.7 Å²	71.7	56%	0.564	41%	0.405	S	S	*	.			trans	-83.1	23.1	-167.8	36.8	0	0	0	0	113.6	P234 V239 H243	P234-T241 HydrophobicContact CG-CG2 4.43Å; V239-T241 PolarHBondContact O-N 3.16Å; T241-H243 PolarHBondContact O-N 3.02Å; T241-H243 VanDerWaalsContact O-N 3.11Å
242	T	49.8	Very low	61.5	Low	94 Å²	94	69.5 Å²	69.5	58%	0.577	39%	0.39	S	S	*	.	S	Bend	trans	-67.8	-15.3	-171	46.7	0	0	0	0	114.3	D240	D240-T242 PolarHBondContact O-N 3.26Å; D240-T242 VanDerWaalsContact O-N 3.15Å
243	H	49.2	Very low	61.6	Low	181 Å²	181	68.8 Å²	68.8	84%	0.838	38%	0.376	S	S	*	.	S	Bend	trans	-142.5	9.3	-176.6	-66.6	-67.7	0	0	0	117.6	T241	T241-H243 PolarHBondContact O-N 3.02Å; T241-H243 VanDerWaalsContact O-N 3.11Å
244	Q	55.3	Low	62	Low	112 Å²	112	69.3 Å²	69.3	52%	0.523	38%	0.377	S	S	.	.			trans	-94.9	124.3	176.4	-85.2	-176.4	-10.8	0	0	112.1	T246	Q244-T246 PolarHBondContact O-N 3.43Å; Q244-T246 VanDerWaalsContact O-N 3.11Å
245	F	60.3	Low	62.6	Low	123 Å²	123	72.1 Å²	72.1	54%	0.539	39%	0.388	S	S	.	.			trans	-70.3	103.9	175.5	-179.1	-95.6	0	0	0	110.3	Y104 W251	Y104-F245 HydrophobicContact CE2-CD2 4.35Å; Y104-F245 HydrophobicContact CE2-CE2 4.28Å; F245-W251 HydrophobicContact CE1-CZ3 4.22Å; F245-W251 AromaticContact CE2-CH2 3.83Å; F245-W251 HydrophobicContact CE2-CH2 3.83Å; F245-W251 HydrophobicContact CE2-CZ3 4.34Å; F245-W251 AromaticContact CZ-CH2 3.4Å; F245-W251 HydrophobicContact CZ-CH2 3.4Å; F245-W251 AromaticContact CZ-CZ3 3.46Å; F245-W251 HydrophobicContact CZ-CZ3 3.46Å; F245-W251 VanDerWaalsContact CZ-CZ3 3.46Å
246	T	65.1	Low	63.4	Low	27 Å²	27	69.1 Å²	69.1	17%	0.166	37%	0.366	C	S	.	.			trans	-91.1	120.7	174.2	32.4	0	0	0	0	109.8	N108 T233 Q244 P248	N108-T246 PolarHBondContact OD1-OG1 3.05Å; T233-T246 HydrophobicContact CG2-CG2 4.44Å; Q244-T246 PolarHBondContact O-N 3.43Å; Q244-T246 VanDerWaalsContact O-N 3.11Å; T246-P248 WeakPolarHBondContact O-CD 3.44Å
247	F	69.9	Low	64.2	Low	40 Å²	40	65.4 Å²	65.4	18%	0.175	35%	0.348	C	S	.	.			trans	-66.7	114.3	179	-177.2	-90.7	0	0	0	110.7	I230 W251 L252	I230-F247 HydrophobicContact CG2-CB 3.75Å; I230-F247 HydrophobicContact CG2-CD1 4.21Å; I230-F247 HydrophobicContact CG2-CG 4.36Å; F247-W251 AromaticContact CD2-CE3 4Å; F247-W251 HydrophobicContact CD2-CE3 4Å; F247-W251 HydrophobicContact CE1-CB 4.36Å; F247-W251 HydrophobicContact CE2-CB 4.36Å; F247-W251 AromaticContact CE2-CE3 3.87Å; F247-W251 HydrophobicContact CE2-CE3 3.87Å; F247-W251 HydrophobicContact CZ-CB 3.98Å; F247-L252 HydrophobicContact CE1-CD2 3.78Å; F247-L252 HydrophobicContact CE1-CG 4.04Å; F247-L252 HydrophobicContact CZ-CD2 4.11Å
248	P	70.4	Confident	65.4	Low	1 Å²	1	62.1 Å²	62.1	1%	0.006	33%	0.334	C	S	.	.			trans	-71.9	133.5	-179.4	-19.4	34.1	0	0	0	111.7	Y104 Q107 T246 A250 W251	Y104-P248 HydrophobicContact CD2-CG 3.74Å; Y104-P248 HydrophobicContact CG-CG 4.42Å; Q107-P248 HydrophobicContact CB-CB 4.39Å; Q107-P248 HydrophobicContact CG-CB 4.46Å; Q107-P248 VanDerWaalsContact OE1-C 3.24Å; T246-P248 WeakPolarHBondContact O-CD 3.44Å; P248-A250 PolarHBondContact O-N 3.08Å; P248-W251 HydrophobicContact CB-CD2 4.43Å; P248-W251 HydrophobicContact CB-CG 4.12Å; P248-W251 HydrophobicContact CG-CD2 4.01Å; P248-W251 HydrophobicContact CG-CG 4.22Å; P248-W251 HydrophobicContact CG-CZ2 4.12Å; P248-W251 VanDerWaalsContact O-CB 3.24Å; P248-W251 WeakPolarHBondContact O-CB 3.47Å; P248-W251 PolarHBondContact O-N 3.33Å
249	A	66.4	Low	66.8	Low	2 Å²	2	58 Å²	58	2%	0.017	30%	0.304	C	S	.	.	T	Hydrogen-bonded Turn	trans	-62.6	-26	176.8	0	0	0	0	0	113.3	F226 W251 L252	F226-A249 HydrophobicContact CD1-CB 4.05Å; F226-A249 HydrophobicContact CE1-CB 3.21Å; F226-A249 HydrophobicContact CZ-CB 3.85Å; A249-W251 PolarHBondContact O-N 2.58Å; A249-W251 VanDerWaalsContact O-N 3.17Å; A249-L252 WeakPolarHBondContact O-CB 3.48Å; A249-L252 WeakPolarHBondContact O-CG 3.26Å; A249-L252 PolarHBondContact O-N 3.47Å
250	A	66.6	Low	68.2	Low	19 Å²	19	55.5 Å²	55.5	16%	0.157	29%	0.288	C	S	.	.	H	α-helix	trans	-58.6	-26.5	172.8	0	0	0	0	0	112.1	P248 L252 T253 M254	P248-A250 PolarHBondContact O-N 3.08Å; A250-L252 PolarHBondContact O-N 2.95Å; A250-T253 PolarHBondContact O-N 3.16Å; A250-T253 VanDerWaalsContact O-N 3.12Å; A250-T253 PolarHBondContact O-OG1 3.18Å; A250-M254 PolarHBondContact O-N 2.9Å
251	W	78.3	Confident	70	Confident	48 Å²	48	51.1 Å²	51.1	18%	0.182	26%	0.264	C	S	.	.	H	α-helix	trans	-70.3	-17	178.6	-67.4	9.5	0	0	0	113.5	L99 G100 Y104 F245 F247 P248 A249 T253 M254 F255	L99-W251 PolarHBondContact O-NE1 2.97Å; G100-W251 PolarHBondContact O-NE1 3.39Å; Y104-W251 HydrophobicContact CD2-CZ2 4.11Å; F245-W251 HydrophobicContact CE1-CZ3 4.22Å; F245-W251 AromaticContact CE2-CH2 3.83Å; F245-W251 HydrophobicContact CE2-CH2 3.83Å; F245-W251 HydrophobicContact CE2-CZ3 4.34Å; F245-W251 AromaticContact CZ-CH2 3.4Å; F245-W251 HydrophobicContact CZ-CH2 3.4Å; F245-W251 AromaticContact CZ-CZ3 3.46Å; F245-W251 HydrophobicContact CZ-CZ3 3.46Å; F245-W251 VanDerWaalsContact CZ-CZ3 3.46Å; F247-W251 AromaticContact CD2-CE3 4Å; F247-W251 HydrophobicContact CD2-CE3 4Å; F247-W251 HydrophobicContact CE1-CB 4.36Å; F247-W251 HydrophobicContact CE2-CB 4.36Å; F247-W251 AromaticContact CE2-CE3 3.87Å; F247-W251 HydrophobicContact CE2-CE3 3.87Å; F247-W251 HydrophobicContact CZ-CB 3.98Å; P248-W251 HydrophobicContact CB-CD2 4.43Å; P248-W251 HydrophobicContact CB-CG 4.12Å; P248-W251 HydrophobicContact CG-CD2 4.01Å; P248-W251 HydrophobicContact CG-CG 4.22Å; P248-W251 HydrophobicContact CG-CZ2 4.12Å; P248-W251 VanDerWaalsContact O-CB 3.24Å; P248-W251 WeakPolarHBondContact O-CB 3.47Å; P248-W251 PolarHBondContact O-N 3.33Å; A249-W251 PolarHBondContact O-N 2.58Å; A249-W251 VanDerWaalsContact O-N 3.17Å; W251-T253 VanDerWaalsContact C-N 3.28Å; W251-T253 PolarHBondContact O-N 3.2Å; W251-M254 HydrophobicContact CB-CE 4.02Å; W251-M254 HydrophobicContact CD2-CE 4.06Å; W251-M254 HydrophobicContact CE3-CE 4.3Å; W251-M254 HydrophobicContact CG-CE 3.95Å; W251-M254 WeakPolarHBondContact O-CA 3.3Å; W251-M254 VanDerWaalsContact O-CB 3.26Å; W251-M254 WeakPolarHBondContact O-CB 3.34Å; W251-M254 PolarHBondContact O-N 3.38Å; W251-M254 VanDerWaalsContact O-N 3.12Å; W251-F255 PolarHBondContact O-N 3.36Å; W251-F255 VanDerWaalsContact O-N 3.08Å
252	L	74.2	Confident	71.6	Confident	18 Å²	18	52.9 Å²	52.9	9%	0.094	27%	0.268	C	S	.	.	H	α-helix	trans	-66	-36.5	171.2	-59.9	169.3	0	0	0	110.9	S225 F247 A249 A250 M254 F255 I335	S225-L252 WeakPolarHBondContact OG-CD1 3.5Å; F247-L252 HydrophobicContact CE1-CD2 3.78Å; F247-L252 HydrophobicContact CE1-CG 4.04Å; F247-L252 HydrophobicContact CZ-CD2 4.11Å; A249-L252 WeakPolarHBondContact O-CB 3.48Å; A249-L252 WeakPolarHBondContact O-CG 3.26Å; A249-L252 PolarHBondContact O-N 3.47Å; A250-L252 PolarHBondContact O-N 2.95Å; L252-M254 VanDerWaalsContact C-N 3.3Å; L252-F255 WeakPolarHBondContact O-CB 3.45Å; L252-F255 PolarHBondContact O-N 3.33Å; L252-I335 HydrophobicContact CD1-CD1 3.73Å; L252-I335 HydrophobicContact CD2-CD1 3.77Å; L252-I335 HydrophobicContact CD2-CG1 4.23Å; L252-I335 HydrophobicContact CG-CD1 4.28Å
253	T	71.6	Confident	73.4	Confident	32 Å²	32	49.9 Å²	49.9	20%	0.196	25%	0.248	C	C	.	.	H	α-helix	trans	-72.1	-25.6	171.8	69.5	0	0	0	0	112.3	I222 A250 W251 F255	I222-T253 HydrophobicContact CD1-CG2 3.73Å; I222-T253 HydrophobicContact CG1-CG2 4.43Å; A250-T253 PolarHBondContact O-N 3.16Å; A250-T253 VanDerWaalsContact O-N 3.12Å; A250-T253 PolarHBondContact O-OG1 3.18Å; W251-T253 VanDerWaalsContact C-N 3.28Å; W251-T253 PolarHBondContact O-N 3.2Å; T253-F255 VanDerWaalsContact C-N 3.32Å
254	M	76.3	Confident	75.1	Confident	39 Å²	39	42.7 Å²	42.7	19%	0.192	22%	0.216	C	C	.	.	H	α-helix	trans	-67.8	-33.1	172.3	-173.2	-179.7	62.7	0	0	112.1	L99 A250 W251 L252 D256 A257 V258	L99-M254 HydrophobicContact CB-CB 3.89Å; L99-M254 HydrophobicContact CB-CG 4.14Å; L99-M254 HydrophobicContact CD1-CB 4.2Å; A250-M254 PolarHBondContact O-N 2.9Å; W251-M254 HydrophobicContact CB-CE 4.02Å; W251-M254 HydrophobicContact CD2-CE 4.06Å; W251-M254 HydrophobicContact CE3-CE 4.3Å; W251-M254 HydrophobicContact CG-CE 3.95Å; W251-M254 WeakPolarHBondContact O-CA 3.3Å; W251-M254 VanDerWaalsContact O-CB 3.26Å; W251-M254 WeakPolarHBondContact O-CB 3.34Å; W251-M254 PolarHBondContact O-N 3.38Å; W251-M254 VanDerWaalsContact O-N 3.12Å; L252-M254 VanDerWaalsContact C-N 3.3Å; M254-D256 VanDerWaalsContact C-N 3.28Å; M254-D256 PolarHBondContact O-N 3.29Å; M254-A257 PolarHBondContact O-N 3Å; M254-V258 HydrophobicContact CG-CG2 4.22Å; M254-V258 WeakPolarHBondContact O-CG2 3.31Å; M254-V258 PolarHBondContact O-N 3.08Å
255	F	77.1	Confident	76.6	Confident	76 Å²	76	40.7 Å²	40.7	33%	0.333	21%	0.212	S	C	.	.	H	α-helix	trans	-59.8	-40.4	179	-174.4	-110.4	0	0	0	111.8	W251 L252 T253 V258 L259 V339 V343	W251-F255 PolarHBondContact O-N 3.36Å; W251-F255 VanDerWaalsContact O-N 3.08Å; L252-F255 WeakPolarHBondContact O-CB 3.45Å; L252-F255 PolarHBondContact O-N 3.33Å; T253-F255 VanDerWaalsContact C-N 3.32Å; F255-V258 PolarHBondContact O-N 3.42Å; F255-L259 HydrophobicContact CD1-CD1 3.55Å; F255-L259 HydrophobicContact CD1-CG 4.11Å; F255-L259 HydrophobicContact CE1-CD1 3.29Å; F255-L259 HydrophobicContact CE1-CD2 4.3Å; F255-L259 HydrophobicContact CE1-CG 3.86Å; F255-L259 HydrophobicContact CE2-CG 4.4Å; F255-L259 HydrophobicContact CG-CD1 4.37Å; F255-L259 HydrophobicContact CZ-CD1 3.9Å; F255-L259 HydrophobicContact CZ-CD2 4.05Å; F255-L259 HydrophobicContact CZ-CG 4Å; F255-L259 WeakPolarHBondContact O-CB 3.48Å; F255-L259 VanDerWaalsContact O-CG 3.26Å; F255-L259 WeakPolarHBondContact O-CG 3.35Å; F255-L259 PolarHBondContact O-N 3.32Å; F255-V339 HydrophobicContact CE1-CG1 4.19Å; F255-V339 HydrophobicContact CZ-CG1 4.09Å; F255-V343 HydrophobicContact CE1-CG2 3.94Å; F255-V343 HydrophobicContact CZ-CG2 4.23Å
256	D	78.1	Confident	77.9	Confident	12 Å²	12	38.8 Å²	38.8	6%	0.064	21%	0.207	C	C	.	.	H	α-helix	trans	-61	-48.2	173.8	-179.3	63	0	0	0	112.1	M217 M254 V258 L259 I260 G346	M217-D256 HydrophobicContact SD-CB 3.7Å; M217-D256 VanDerWaalsContact SD-CG 3.58Å; M254-D256 VanDerWaalsContact C-N 3.28Å; M254-D256 PolarHBondContact O-N 3.29Å; D256-V258 VanDerWaalsContact C-N 3.33Å; D256-V258 PolarHBondContact O-N 3.34Å; D256-L259 WeakPolarHBondContact O-CB 3.05Å; D256-L259 PolarHBondContact O-N 2.92Å; D256-L259 VanDerWaalsContact O-N 3.15Å; D256-I260 WeakPolarHBondContact O-CG1 3.45Å; D256-I260 PolarHBondContact O-N 3.38Å; D256-G346 WeakPolarHBondContact OD1-CA 3.17Å
257	A	78	Confident	79	Confident	18 Å²	18	38 Å²	38	15%	0.149	20%	0.201	C	C	.	.	H	α-helix	trans	-58.8	-42.3	176.7	0	0	0	0	0	112.7	L99 M254 I260 L261	L99-A257 HydrophobicContact CD1-CB 4.36Å; M254-A257 PolarHBondContact O-N 3Å; A257-I260 PolarHBondContact O-N 2.95Å; A257-L261 WeakPolarHBondContact O-CG 3.39Å; A257-L261 PolarHBondContact O-N 3.47Å; A257-L261 VanDerWaalsContact O-N 3.08Å
258	V	82.3	Confident	79.7	Confident	59 Å²	59	40 Å²	40	36%	0.358	21%	0.214	S	C	.	.	H	α-helix	trans	-67.1	-41.1	176.4	172.6	0	0	0	0	111.3	M254 F255 D256 L261 M262	M254-V258 HydrophobicContact CG-CG2 4.22Å; M254-V258 WeakPolarHBondContact O-CG2 3.31Å; M254-V258 PolarHBondContact O-N 3.08Å; F255-V258 PolarHBondContact O-N 3.42Å; D256-V258 VanDerWaalsContact C-N 3.33Å; D256-V258 PolarHBondContact O-N 3.34Å; V258-L261 WeakPolarHBondContact O-CB 3.3Å; V258-L261 PolarHBondContact O-N 3.28Å; V258-M262 PolarHBondContact O-N 3.31Å
259	L	84.1	Confident	80.6	Confident	20 Å²	20	47.8 Å²	47.8	11%	0.105	25%	0.248	C	C	.	.	H	α-helix	trans	-60.7	-46.1	175.2	-80.6	174.4	0	0	0	111.2	F255 D256 L261 M262 L263 V343	F255-L259 HydrophobicContact CD1-CD1 3.55Å; F255-L259 HydrophobicContact CD1-CG 4.11Å; F255-L259 HydrophobicContact CE1-CD1 3.29Å; F255-L259 HydrophobicContact CE1-CD2 4.3Å; F255-L259 HydrophobicContact CE1-CG 3.86Å; F255-L259 HydrophobicContact CE2-CG 4.4Å; F255-L259 HydrophobicContact CG-CD1 4.37Å; F255-L259 HydrophobicContact CZ-CD1 3.9Å; F255-L259 HydrophobicContact CZ-CD2 4.05Å; F255-L259 HydrophobicContact CZ-CG 4Å; F255-L259 WeakPolarHBondContact O-CB 3.48Å; F255-L259 VanDerWaalsContact O-CG 3.26Å; F255-L259 WeakPolarHBondContact O-CG 3.35Å; F255-L259 PolarHBondContact O-N 3.32Å; D256-L259 WeakPolarHBondContact O-CB 3.05Å; D256-L259 PolarHBondContact O-N 2.92Å; D256-L259 VanDerWaalsContact O-N 3.15Å; L259-L261 VanDerWaalsContact C-N 3.32Å; L259-L261 PolarHBondContact O-N 3.12Å; L259-M262 PolarHBondContact O-N 2.64Å; L259-M262 VanDerWaalsContact O-N 3.14Å; L259-L263 HydrophobicContact CB-CD1 4.37Å; L259-L263 WeakPolarHBondContact O-CB 3.5Å; L259-L263 WeakPolarHBondContact O-CG 3.29Å; L259-L263 PolarHBondContact O-N 3.34Å; L259-V343 HydrophobicContact CD1-CB 4.39Å; L259-V343 HydrophobicContact CD1-CG2 3.92Å; L259-V343 HydrophobicContact CD2-CG2 4.3Å
260	I	83	Confident	81.6	Confident	18 Å²	18	50.9 Å²	50.9	9%	0.092	27%	0.266	C	S	.	.	H	α-helix	trans	-60	-44.7	177.9	-69.4	166.4	0	0	0	110.6	D256 A257 M262 L263 I264 E349	D256-I260 WeakPolarHBondContact O-CG1 3.45Å; D256-I260 PolarHBondContact O-N 3.38Å; A257-I260 PolarHBondContact O-N 2.95Å; I260-M262 VanDerWaalsContact C-N 3.26Å; I260-M262 PolarHBondContact O-N 3.24Å; I260-L263 PolarHBondContact O-N 3.17Å; I260-I264 HydrophobicContact CG2-CD1 3.42Å; I260-I264 VanDerWaalsContact CG2-CD1 3.42Å; I260-I264 HydrophobicContact CG2-CG1 4.06Å; I260-I264 WeakPolarHBondContact O-CB 3.33Å; I260-I264 WeakPolarHBondContact O-CG1 3.33Å; I260-I264 PolarHBondContact O-N 2.95Å; I260-E349 VanDerWaalsContact CD1-CD 3.45Å; I260-E349 HydrophobicContact CD1-CG 4.43Å; I260-E349 VanDerWaalsContact CD1-OE2 3.3Å; I260-E349 WeakPolarHBondContact CD1-OE2 3.33Å
261	L	82.4	Confident	82.6	Confident	43 Å²	43	52.4 Å²	52.4	23%	0.225	27%	0.273	C	S	.	.	H	α-helix	trans	-59.2	-35.2	176.1	-83.3	174.9	0	0	0	113.4	N92 I96 A257 V258 L259 P265	N92-L261 HydrophobicContact CB-CD1 4Å; N92-L261 HydrophobicContact CB-CD2 3.73Å; N92-L261 HydrophobicContact CB-CG 4.28Å; N92-L261 WeakPolarHBondContact OD1-CD2 3.32Å; N92-L261 WeakPolarHBondContact OD1-CG 3.44Å; I96-L261 HydrophobicContact CD1-CD1 3.88Å; A257-L261 WeakPolarHBondContact O-CG 3.39Å; A257-L261 PolarHBondContact O-N 3.47Å; A257-L261 VanDerWaalsContact O-N 3.08Å; V258-L261 WeakPolarHBondContact O-CB 3.3Å; V258-L261 PolarHBondContact O-N 3.28Å; L259-L261 VanDerWaalsContact C-N 3.32Å; L259-L261 PolarHBondContact O-N 3.12Å; L261-P265 WeakPolarHBondContact O-CD 3.49Å; L261-P265 WeakPolarHBondContact O-CG 3.33Å
262	M	85.3	Confident	83	Confident	128 Å²	128	51.9 Å²	51.9	63%	0.631	27%	0.274	S	S	*	.	H	α-helix	trans	-79.9	-41.5	176.6	-173.4	-172	-68.1	0	0	112.3	V258 L259 I260 P265 L266	V258-M262 PolarHBondContact O-N 3.31Å; L259-M262 PolarHBondContact O-N 2.64Å; L259-M262 VanDerWaalsContact O-N 3.14Å; I260-M262 VanDerWaalsContact C-N 3.26Å; I260-M262 PolarHBondContact O-N 3.24Å; M262-P265 WeakPolarHBondContact O-CD 3.28Å; M262-L266 PolarHBondContact O-N 3.12Å
263	L	86.9	Confident	83.7	Confident	32 Å²	32	53.3 Å²	53.3	17%	0.168	28%	0.284	C	S	.	.	H	α-helix	trans	-79.1	-28.4	-172	-71	176	0	0	0	112.9	L259 I260 L266 K267 I347 I350	L259-L263 HydrophobicContact CB-CD1 4.37Å; L259-L263 WeakPolarHBondContact O-CB 3.5Å; L259-L263 WeakPolarHBondContact O-CG 3.29Å; L259-L263 PolarHBondContact O-N 3.34Å; I260-L263 PolarHBondContact O-N 3.17Å; L263-L266 HydrophobicContact CD2-CD2 3.98Å; L263-L266 PolarHBondContact O-N 3.06Å; L263-K267 VanDerWaalsContact O-CB 3.29Å; L263-K267 WeakPolarHBondContact O-CB 3.47Å; L263-K267 PolarHBondContact O-N 3.18Å; L263-I347 HydrophobicContact CD1-CG1 3.85Å; L263-I350 HydrophobicContact CB-CD1 3.25Å; L263-I350 HydrophobicContact CD1-CD1 4.06Å; L263-I350 HydrophobicContact CG-CD1 4.31Å
264	I	85.7	Confident	84.5	Confident	30 Å²	30	55.3 Å²	55.3	15%	0.154	29%	0.293	C	S	.	.	H	α-helix	trans	-62.1	-54.3	176	-74	170	0	0	0	111.2	Y88 I260 L266 K267 D268 I350 I354	Y88-I264 WeakPolarHBondContact OH-CD1 3.35Å; I260-I264 HydrophobicContact CG2-CD1 3.42Å; I260-I264 VanDerWaalsContact CG2-CD1 3.42Å; I260-I264 HydrophobicContact CG2-CG1 4.06Å; I260-I264 WeakPolarHBondContact O-CB 3.33Å; I260-I264 WeakPolarHBondContact O-CG1 3.33Å; I260-I264 PolarHBondContact O-N 2.95Å; I264-L266 VanDerWaalsContact C-N 3.28Å; I264-L266 PolarHBondContact O-N 2.6Å; I264-K267 PolarHBondContact O-N 3.38Å; I264-D268 PolarHBondContact O-N 3.2Å; I264-I350 HydrophobicContact CG1-CD1 4.27Å; I264-I350 HydrophobicContact CG1-CG1 4.29Å; I264-I354 HydrophobicContact CD1-CD1 4.1Å; I264-I354 HydrophobicContact CG1-CD1 4.43Å
265	P	86.5	Confident	85	Confident	70 Å²	70	55.5 Å²	55.5	46%	0.455	30%	0.295	S	S	.	.	H	α-helix	trans	-58.2	-40.7	175.1	-24.4	33.3	0	0	0	112.5	L261 M262 K267 D268 K269	L261-P265 WeakPolarHBondContact O-CD 3.49Å; L261-P265 WeakPolarHBondContact O-CG 3.33Å; M262-P265 WeakPolarHBondContact O-CD 3.28Å; P265-K267 PolarHBondContact O-N 3.36Å; P265-D268 PolarHBondContact O-N 3.35Å; P265-K269 WeakPolarHBondContact O-CB 3.44Å; P265-K269 WeakPolarHBondContact O-CG 3.27Å; P265-K269 PolarHBondContact O-N 2.98Å
266	L	88.1	Confident	85.5	Confident	82 Å²	82	59.5 Å²	59.5	43%	0.429	31%	0.312	S	S	.	.	H	α-helix	trans	-60.3	-46.2	177.1	-179.5	65.4	0	0	0	111.1	M262 L263 I264 V270 V271	M262-L266 PolarHBondContact O-N 3.12Å; L263-L266 HydrophobicContact CD2-CD2 3.98Å; L263-L266 PolarHBondContact O-N 3.06Å; I264-L266 VanDerWaalsContact C-N 3.28Å; I264-L266 PolarHBondContact O-N 2.6Å; L266-V270 HydrophobicContact CD1-CB 4.02Å; L266-V270 HydrophobicContact CD1-CG1 4.45Å; L266-V270 HydrophobicContact CD1-CG2 3.95Å; L266-V270 WeakPolarHBondContact O-CA 3.42Å; L266-V270 WeakPolarHBondContact O-CB 3.36Å; L266-V270 PolarHBondContact O-N 2.67Å; L266-V271 PolarHBondContact O-N 3.08Å; L266-V271 VanDerWaalsContact O-N 3.1Å
267	K	87.1	Confident	86	Confident	11 Å²	11	69.3 Å²	69.3	5%	0.048	35%	0.348	C	S	.	.	I	π-helix	trans	-62	-55.1	177.2	178.2	-140.5	171.7	173.7	0	111.1	L263 I264 P265 K269 V271 D272 I350	L263-K267 VanDerWaalsContact O-CB 3.29Å; L263-K267 WeakPolarHBondContact O-CB 3.47Å; L263-K267 PolarHBondContact O-N 3.18Å; I264-K267 PolarHBondContact O-N 3.38Å; P265-K267 PolarHBondContact O-N 3.36Å; K267-K269 PolarHBondContact O-N 3.47Å; K267-V271 PolarHBondContact O-N 3.37Å; K267-V271 VanDerWaalsContact O-N 3.16Å; K267-D272 WeakPolarHBondContact CE-OD2 3.36Å; K267-D272 PolarHBondContact O-N 3.46Å; K267-I350 HydrophobicContact CB-CG2 4.48Å; K267-I350 HydrophobicContact CD-CG2 3.58Å; K267-I350 HydrophobicContact CG-CG2 4.31Å
268	D	86.4	Confident	86.5	Confident	81 Å²	81	77.4 Å²	77.4	43%	0.433	38%	0.375	S	S	.	.	I	π-helix	trans	-70	-33.8	-171.1	-70.5	-5.9	0	0	0	112.9	I264 P265 P273	I264-D268 PolarHBondContact O-N 3.2Å; P265-D268 PolarHBondContact O-N 3.35Å; D268-P273 WeakPolarHBondContact O-CD 3.46Å
269	K	87.8	Confident	86.4	Confident	166 Å²	166	77.8 Å²	77.8	72%	0.722	39%	0.391	S	S	*	.	I	π-helix	trans	-97.2	-24.3	-175.9	-61.5	-65.5	-173.8	175.8	0	114	P265 K267 P273	P265-K269 WeakPolarHBondContact O-CB 3.44Å; P265-K269 WeakPolarHBondContact O-CG 3.27Å; P265-K269 PolarHBondContact O-N 2.98Å; K267-K269 PolarHBondContact O-N 3.47Å; K269-P273 WeakPolarHBondContact O-CG 3.44Å
270	V	89	Confident	86.3	Confident	66 Å²	66	82.3 Å²	82.3	40%	0.4	42%	0.415	S	S	.	.	I	π-helix	trans	-116.7	-60.3	-175.2	-173.1	0	0	0	0	110.7	L266 I274	L266-V270 HydrophobicContact CD1-CB 4.02Å; L266-V270 HydrophobicContact CD1-CG1 4.45Å; L266-V270 HydrophobicContact CD1-CG2 3.95Å; L266-V270 WeakPolarHBondContact O-CA 3.42Å; L266-V270 WeakPolarHBondContact O-CB 3.36Å; L266-V270 PolarHBondContact O-N 2.67Å; V270-I274 HydrophobicContact CG1-CD1 3.65Å; V270-I274 WeakPolarHBondContact O-CB 3.43Å; V270-I274 VanDerWaalsContact O-CD1 3.3Å; V270-I274 WeakPolarHBondContact O-CD1 3.44Å; V270-I274 WeakPolarHBondContact O-CG1 3.3Å; V270-I274 PolarHBondContact O-N 3.22Å; V270-I274 VanDerWaalsContact O-N 3.13Å
271	V	87.1	Confident	86.1	Confident	51 Å²	51	86.2 Å²	86.2	31%	0.309	44%	0.435	S	S	.	.	I	π-helix	trans	-65.4	-52.6	-171.6	-179.7	0	0	0	0	111.7	L266 K267 I274 L275	L266-V271 PolarHBondContact O-N 3.08Å; L266-V271 VanDerWaalsContact O-N 3.1Å; K267-V271 PolarHBondContact O-N 3.37Å; K267-V271 VanDerWaalsContact O-N 3.16Å; V271-I274 PolarHBondContact O-N 3.12Å; V271-L275 HydrophobicContact CG1-CD1 3.46Å; V271-L275 VanDerWaalsContact CG1-CD1 3.46Å; V271-L275 WeakPolarHBondContact O-CB 3.43Å; V271-L275 WeakPolarHBondContact O-CD1 3.48Å; V271-L275 WeakPolarHBondContact O-CG 3.33Å; V271-L275 PolarHBondContact O-N 3.26Å
272	D	86.4	Confident	85.8	Confident	38 Å²	38	85.6 Å²	85.6	20%	0.203	43%	0.434	C	S	.	.	H	α-helix	trans	-64.1	-45	-176.6	-77.7	-0.3	0	0	0	112.4	K267 I274 L275 K276	K267-D272 WeakPolarHBondContact CE-OD2 3.36Å; K267-D272 PolarHBondContact O-N 3.46Å; D272-I274 VanDerWaalsContact C-N 3.35Å; D272-I274 PolarHBondContact O-N 2.82Å; D272-L275 PolarHBondContact O-N 3.02Å; D272-K276 VanDerWaalsContact O-CB 3.27Å; D272-K276 WeakPolarHBondContact O-CB 3.3Å; D272-K276 PolarHBondContact O-N 3.19Å
273	P	87.9	Confident	85.7	Confident	47 Å²	47	81.2 Å²	81.2	31%	0.305	42%	0.416	S	S	.	.	H	α-helix	trans	-61.6	-37.9	173.4	-28.4	38.7	0	0	0	113.7	D268 K269 K276 R277	D268-P273 WeakPolarHBondContact O-CD 3.46Å; K269-P273 WeakPolarHBondContact O-CG 3.44Å; P273-K276 PolarHBondContact O-N 3.06Å; P273-R277 WeakPolarHBondContact O-CG 3.49Å; P273-R277 PolarHBondContact O-N 3.05Å
274	I	88.9	Confident	85.6	Confident	74 Å²	74	81.6 Å²	81.6	38%	0.379	42%	0.421	S	S	.	.	H	α-helix	trans	-66.1	-47.1	176.9	-70.3	168.2	0	0	0	110.7	V270 V271 D272 K276 R277 R278	V270-I274 HydrophobicContact CG1-CD1 3.65Å; V270-I274 WeakPolarHBondContact O-CB 3.43Å; V270-I274 VanDerWaalsContact O-CD1 3.3Å; V270-I274 WeakPolarHBondContact O-CD1 3.44Å; V270-I274 WeakPolarHBondContact O-CG1 3.3Å; V270-I274 PolarHBondContact O-N 3.22Å; V270-I274 VanDerWaalsContact O-N 3.13Å; V271-I274 PolarHBondContact O-N 3.12Å; D272-I274 VanDerWaalsContact C-N 3.35Å; D272-I274 PolarHBondContact O-N 2.82Å; I274-K276 VanDerWaalsContact C-N 3.29Å; I274-K276 PolarHBondContact O-N 3.04Å; I274-R277 PolarHBondContact O-N 2.81Å; I274-R278 PolarHBondContact O-N 3.06Å
275	L	87.3	Confident	85.6	Confident	44 Å²	44	80.7 Å²	80.7	23%	0.23	42%	0.417	C	S	.	.	H	α-helix	trans	-60.3	-40.6	175.8	-79.3	152.3	0	0	0	111.5	V271 D272 R278 G279 L280 L281	V271-L275 HydrophobicContact CG1-CD1 3.46Å; V271-L275 VanDerWaalsContact CG1-CD1 3.46Å; V271-L275 WeakPolarHBondContact O-CB 3.43Å; V271-L275 WeakPolarHBondContact O-CD1 3.48Å; V271-L275 WeakPolarHBondContact O-CG 3.33Å; V271-L275 PolarHBondContact O-N 3.26Å; D272-L275 PolarHBondContact O-N 3.02Å; L275-R278 PolarHBondContact O-N 3.43Å; L275-G279 PolarHBondContact O-N 3.2Å; L275-L280 HydrophobicContact CD2-CB 4.08Å; L275-L280 PolarHBondContact O-N 3.37Å; L275-L281 HydrophobicContact CB-CD1 4.48Å
276	K	87.4	Confident	85.7	Confident	159 Å²	159	82.1 Å²	82.1	69%	0.691	42%	0.415	S	S	*	.	H	α-helix	trans	-62.9	-44.8	175.7	-168.5	175.9	179.8	179.8	0	111.7	D272 P273 I274 R278 G279 L281	D272-K276 VanDerWaalsContact O-CB 3.27Å; D272-K276 WeakPolarHBondContact O-CB 3.3Å; D272-K276 PolarHBondContact O-N 3.19Å; P273-K276 PolarHBondContact O-N 3.06Å; I274-K276 VanDerWaalsContact C-N 3.29Å; I274-K276 PolarHBondContact O-N 3.04Å; K276-R278 PolarHBondContact O-N 3.45Å; K276-G279 PolarHBondContact O-N 2.99Å; K276-G279 VanDerWaalsContact O-N 3.11Å; K276-L281 HydrophobicContact CB-CD1 3.94Å
277	R	88.1	Confident	85.8	Confident	218 Å²	218	79.6 Å²	79.6	82%	0.823	40%	0.4	S	S	*	.	H	α-helix	trans	-61.2	-33.6	176.1	-76.4	178.5	-171.5	174.2	3.7	112.5	P273 I274 G279	P273-R277 WeakPolarHBondContact O-CG 3.49Å; P273-R277 PolarHBondContact O-N 3.05Å; I274-R277 PolarHBondContact O-N 2.81Å; R277-G279 VanDerWaalsContact C-N 3.33Å
278	R	88.1	Confident	86	Confident	188 Å²	188	79.1 Å²	79.1	71%	0.709	40%	0.398	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.6	-0.9	177.5	-66.5	-175.1	178.9	-170.8	0.4	114	I274 L275 K276 L280	I274-R278 PolarHBondContact O-N 3.06Å; L275-R278 PolarHBondContact O-N 3.43Å; K276-R278 PolarHBondContact O-N 3.45Å; R278-L280 HydrophobicContact CB-CB 4.46Å; R278-L280 HydrophobicContact CB-CD1 4.05Å; R278-L280 HydrophobicContact CB-CG 4.19Å; R278-L280 PolarHBondContact O-N 3.15Å
279	G	81	Confident	86.4	Confident	68 Å²	68	75.5 Å²	75.5	70%	0.701	38%	0.379	S	S	*	.	T	Hydrogen-bonded Turn	trans	67.2	14.6	-175.4	0	0	0	0	0	114.2	L275 K276 R277	L275-G279 PolarHBondContact O-N 3.2Å; K276-G279 PolarHBondContact O-N 2.99Å; K276-G279 VanDerWaalsContact O-N 3.11Å; R277-G279 VanDerWaalsContact C-N 3.33Å
280	L	82.4	Confident	86.7	Confident	115 Å²	115	70.3 Å²	70.3	60%	0.602	36%	0.362	S	S	*	.			trans	-103.4	17.5	-174.2	-67.7	173.7	0	0	0	112.8	L275 R278 P282	L275-L280 HydrophobicContact CD2-CB 4.08Å; L275-L280 PolarHBondContact O-N 3.37Å; R278-L280 HydrophobicContact CB-CB 4.46Å; R278-L280 HydrophobicContact CB-CD1 4.05Å; R278-L280 HydrophobicContact CB-CG 4.19Å; R278-L280 PolarHBondContact O-N 3.15Å; L280-P282 WeakPolarHBondContact O-CD 3.38Å
281	L	78.1	Confident	87	Confident	99 Å²	99	67.1 Å²	67.1	52%	0.518	34%	0.343	S	S	.	.			trans	-60.2	113.9	-177.5	-160.3	104.5	0	0	0	109.9	L275 K276	L275-L281 HydrophobicContact CB-CD1 4.48Å; K276-L281 HydrophobicContact CB-CD1 3.94Å
282	P	76.6	Confident	87.5	Confident	31 Å²	31	64.7 Å²	64.7	20%	0.201	33%	0.328	C	S	.	.			trans	-69.6	145.5	-175.1	25.4	-31.5	0	0	0	111.3	L280 K286 R287	L280-P282 WeakPolarHBondContact O-CD 3.38Å; P282-K286 HydrophobicContact CB-CB 3.85Å; P282-R287 HydrophobicContact CB-CG 4.02Å; P282-R287 HydrophobicContact CG-CG 3.63Å
283	S	82.9	Confident	88	Confident	36 Å²	36	67.5 Å²	67.5	25%	0.252	34%	0.338	S	S	.	.			trans	-62.6	158.7	168.5	63	0	0	0	0	110.5	L285 K286 R287 D442	S283-L285 PolarHBondContact O-N 3.49Å; S283-K286 PolarHBondContact O-N 2.91Å; S283-K286 WeakPolarHBondContact OG-CG 3.42Å; S283-K286 PolarHBondContact OG-N 3.48Å; S283-R287 PolarHBondContact O-N 3.3Å; S283-D442 PolarHBondContact OG-OD2 3.08Å
284	S	84.3	Confident	88.5	Confident	40 Å²	40	67.8 Å²	67.8	28%	0.28	34%	0.335	S	S	.	.	H	α-helix	trans	-55.7	-37.9	-179.6	-48.2	0	0	0	0	112.5	R287 I288	S284-R287 WeakPolarHBondContact O-CB 3.35Å; S284-R287 PolarHBondContact O-N 2.97Å; S284-I288 VanDerWaalsContact O-CG1 3.3Å; S284-I288 WeakPolarHBondContact O-CG1 3.38Å; S284-I288 PolarHBondContact O-N 3.31Å
285	L	86.3	Confident	88.9	Confident	11 Å²	11	64.2 Å²	64.2	6%	0.058	32%	0.317	C	S	.	.	H	α-helix	trans	-66.2	-40.8	174.7	-63.4	177.7	0	0	0	112.3	V203 S283 R287 I288 A289 F359 F434 S438 Y441	V203-L285 HydrophobicContact CG1-CD2 4.3Å; V203-L285 HydrophobicContact CG2-CD2 4.14Å; S283-L285 PolarHBondContact O-N 3.49Å; L285-R287 VanDerWaalsContact C-N 3.35Å; L285-R287 PolarHBondContact O-N 3.44Å; L285-I288 HydrophobicContact CD2-CD1 4.34Å; L285-I288 WeakPolarHBondContact O-CB 3.44Å; L285-I288 PolarHBondContact O-N 2.97Å; L285-A289 PolarHBondContact O-N 3.47Å; L285-F359 HydrophobicContact CD2-CD2 4.46Å; L285-F359 HydrophobicContact CD2-CE1 4.32Å; L285-F359 HydrophobicContact CD2-CE2 4.18Å; L285-F359 HydrophobicContact CD2-CZ 4.1Å; L285-F359 HydrophobicContact CG-CE2 4.45Å; L285-F434 HydrophobicContact CD2-CZ 4.08Å; L285-F434 WeakPolarHBondContact O-CE1 3.35Å; L285-S438 WeakPolarHBondContact CB-OG 3.37Å; L285-Y441 HydrophobicContact CD1-CD1 3.44Å; L285-Y441 VanDerWaalsContact CD1-CD1 3.44Å; L285-Y441 HydrophobicContact CD1-CE1 3.97Å; L285-Y441 HydrophobicContact CD1-CG 3.91Å
286	K	88.1	Confident	89.4	Confident	99 Å²	99	64 Å²	64	43%	0.43	32%	0.315	S	S	.	.	H	α-helix	trans	-65.4	-37.6	174.9	-72	175.5	-176.2	175.2	0	112.2	P282 S283 I288 A289 V290 D442	P282-K286 HydrophobicContact CB-CB 3.85Å; S283-K286 PolarHBondContact O-N 2.91Å; S283-K286 WeakPolarHBondContact OG-CG 3.42Å; S283-K286 PolarHBondContact OG-N 3.48Å; K286-I288 VanDerWaalsContact C-N 3.33Å; K286-A289 PolarHBondContact O-N 3.12Å; K286-V290 WeakPolarHBondContact O-CG2 3.23Å; K286-V290 PolarHBondContact O-N 3.14Å; K286-D442 VanDerWaalsContact CE-OD2 3.3Å; K286-D442 WeakPolarHBondContact CE-OD2 3.39Å; K286-D442 IonicContact NZ-OD2 2.7Å
287	R	90	Very high	89.9	Confident	30 Å²	30	57.9 Å²	57.9	11%	0.113	29%	0.292	C	S	.	.	H	α-helix	trans	-57.8	-47.8	171.9	-71.3	173.1	54.6	-160.7	-10.3	110.5	P282 S283 S284 L285 A289 V290 G291 F351 A355 E358	P282-R287 HydrophobicContact CB-CG 4.02Å; P282-R287 HydrophobicContact CG-CG 3.63Å; S283-R287 PolarHBondContact O-N 3.3Å; S284-R287 WeakPolarHBondContact O-CB 3.35Å; S284-R287 PolarHBondContact O-N 2.97Å; L285-R287 VanDerWaalsContact C-N 3.35Å; L285-R287 PolarHBondContact O-N 3.44Å; R287-A289 VanDerWaalsContact C-N 3.31Å; R287-A289 PolarHBondContact O-N 3.26Å; R287-V290 WeakPolarHBondContact O-CB 3.19Å; R287-V290 PolarHBondContact O-N 2.97Å; R287-V290 VanDerWaalsContact O-N 3.1Å; R287-G291 PolarHBondContact O-N 3.45Å; R287-F351 CarbonylContact C-O 3.56Å; R287-F351 HydrophobicContact CB-CD1 4.41Å; R287-F351 CarbonylContact O-C 3.29Å; R287-A355 HydrophobicContact CB-CB 3.92Å; R287-E358 IonicContact CZ-OE2 3.02Å; R287-E358 VanDerWaalsContact CZ-OE2 3.28Å; R287-E358 IonicContact NH1-OE2 3.62Å; R287-E358 PolarHBondContact NH1-OE2 3.38Å; R287-E358 IonicContact NH2-OE1 2.72Å; R287-E358 IonicContact NH2-OE2 2.97Å; R287-E358 PolarHBondContact NH2-OE2 2.99Å
288	I	93	Very high	90.3	Very high	0 Å²	0	47.5 Å²	47.5	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-57.8	-44	177	-65.8	163.5	0	0	0	111.4	V203 L207 S284 L285 K286 V290 G291 M292 F351 A355 F359 F434	V203-I288 HydrophobicContact CG1-CD1 4.48Å; L207-I288 HydrophobicContact CD2-CG2 3.79Å; S284-I288 VanDerWaalsContact O-CG1 3.3Å; S284-I288 WeakPolarHBondContact O-CG1 3.38Å; S284-I288 PolarHBondContact O-N 3.31Å; L285-I288 HydrophobicContact CD2-CD1 4.34Å; L285-I288 WeakPolarHBondContact O-CB 3.44Å; L285-I288 PolarHBondContact O-N 2.97Å; K286-I288 VanDerWaalsContact C-N 3.33Å; I288-V290 VanDerWaalsContact C-N 3.32Å; I288-V290 PolarHBondContact O-N 2.98Å; I288-G291 PolarHBondContact O-N 3.47Å; I288-G291 VanDerWaalsContact O-N 3.14Å; I288-M292 HydrophobicContact CG2-CE 3.92Å; I288-M292 HydrophobicContact CG2-CG 4.43Å; I288-M292 HydrophobicContact CG2-SD 4.45Å; I288-M292 WeakPolarHBondContact O-CG 3.13Å; I288-M292 PolarHBondContact O-N 3.02Å; I288-F351 WeakPolarHBondContact CA-O 3.36Å; I288-F351 PolarHBondContact N-O 2.83Å; I288-A355 HydrophobicContact CG1-CB 4.06Å; I288-F359 HydrophobicContact CD1-CB 4.47Å; I288-F434 HydrophobicContact CB-CE1 3.98Å; I288-F434 HydrophobicContact CB-CZ 4.01Å; I288-F434 HydrophobicContact CG2-CE1 3.74Å; I288-F434 HydrophobicContact CG2-CE2 4.47Å; I288-F434 HydrophobicContact CG2-CZ 3.61Å
289	A	93.9	Very high	90.8	Very high	5 Å²	5	38.6 Å²	38.6	4%	0.041	22%	0.219	C	C	.	.	H	α-helix	trans	-62	-37.9	177.4	0	0	0	0	0	112.9	L285 K286 R287 M292 F293 L431 F434 L435	L285-A289 PolarHBondContact O-N 3.47Å; K286-A289 PolarHBondContact O-N 3.12Å; R287-A289 VanDerWaalsContact C-N 3.31Å; R287-A289 PolarHBondContact O-N 3.26Å; A289-M292 WeakPolarHBondContact O-CB 3.38Å; A289-M292 PolarHBondContact O-N 3.42Å; A289-F293 PolarHBondContact O-N 3.26Å; A289-L431 HydrophobicContact CB-CD1 4.11Å; A289-L431 VanDerWaalsContact O-CD1 3.3Å; A289-L431 WeakPolarHBondContact O-CD1 3.29Å; A289-F434 HydrophobicContact CB-CD1 3.93Å; A289-F434 HydrophobicContact CB-CE1 4.11Å; A289-L435 HydrophobicContact CB-CD2 3.66Å; A289-L435 HydrophobicContact CB-CG 4.35Å
290	V	94	Very high	91.6	Very high	57 Å²	57	37.8 Å²	37.8	35%	0.345	20%	0.2	S	C	.	.	H	α-helix	trans	-61.7	-44.2	173.2	171.7	0	0	0	0	110.7	K286 R287 I288 M292 F293 F294 F351	K286-V290 WeakPolarHBondContact O-CG2 3.23Å; K286-V290 PolarHBondContact O-N 3.14Å; R287-V290 WeakPolarHBondContact O-CB 3.19Å; R287-V290 PolarHBondContact O-N 2.97Å; R287-V290 VanDerWaalsContact O-N 3.1Å; I288-V290 VanDerWaalsContact C-N 3.32Å; I288-V290 PolarHBondContact O-N 2.98Å; V290-M292 PolarHBondContact O-N 3.37Å; V290-F293 WeakPolarHBondContact O-CB 3.18Å; V290-F293 PolarHBondContact O-N 2.97Å; V290-F294 HydrophobicContact CG1-CD2 3.77Å; V290-F294 HydrophobicContact CG1-CE2 3.51Å; V290-F294 WeakPolarHBondContact O-CD2 3.24Å; V290-F294 PolarHBondContact O-N 3.26Å; V290-F294 VanDerWaalsContact O-N 3.11Å; V290-F351 HydrophobicContact CB-CB 4.5Å; V290-F351 HydrophobicContact CG1-CB 4.35Å; V290-F351 HydrophobicContact CG1-CD1 4.31Å; V290-F351 HydrophobicContact CG1-CD2 4.3Å; V290-F351 HydrophobicContact CG1-CG 4.07Å
291	G	95.6	Very high	92.3	Very high	0 Å²	0	33.4 Å²	33.4	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-62	-44.1	175.1	0	0	0	0	0	112.1	R287 I288 F293 F294 V295 S348	R287-G291 PolarHBondContact O-N 3.45Å; I288-G291 PolarHBondContact O-N 3.47Å; I288-G291 VanDerWaalsContact O-N 3.14Å; G291-F293 PolarHBondContact O-N 3.43Å; G291-F294 PolarHBondContact O-N 3.03Å; G291-F294 VanDerWaalsContact O-N 3.1Å; G291-V295 PolarHBondContact O-N 3.42Å; G291-S348 WeakPolarHBondContact O-CB 3.3Å; G291-S348 PolarHBondContact O-OG 3.01Å
292	M	96.6	Very high	93.2	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-58.2	-34.1	175	-74.8	-175.5	174.9	0	0	113.4	A206 L207 I288 A289 V290 M296 Q427 L431 F434	A206-M292 VanDerWaalsContact O-CE 3.28Å; A206-M292 WeakPolarHBondContact O-CE 3.36Å; L207-M292 HydrophobicContact CD2-CE 3.65Å; L207-M292 HydrophobicContact CG-CE 4.24Å; I288-M292 HydrophobicContact CG2-CE 3.92Å; I288-M292 HydrophobicContact CG2-CG 4.43Å; I288-M292 HydrophobicContact CG2-SD 4.45Å; I288-M292 WeakPolarHBondContact O-CG 3.13Å; I288-M292 PolarHBondContact O-N 3.02Å; A289-M292 WeakPolarHBondContact O-CB 3.38Å; A289-M292 PolarHBondContact O-N 3.42Å; V290-M292 PolarHBondContact O-N 3.37Å; M292-M296 PolarHBondContact O-N 2.96Å; M292-Q427 PolarHBondContact O-NE2 2.97Å; M292-L431 HydrophobicContact CB-CD1 3.92Å; M292-F434 HydrophobicContact CE-CD1 4.31Å; M292-F434 HydrophobicContact CE-CD2 3.98Å; M292-F434 HydrophobicContact CE-CE2 4.19Å; M292-F434 HydrophobicContact CE-CG 4.03Å; M292-F434 HydrophobicContact CE-CZ 4.45Å; M292-F434 HydrophobicContact SD-CB 3.99Å; M292-F434 HydrophobicContact SD-CD1 3.81Å; M292-F434 HydrophobicContact SD-CD2 4.37Å; M292-F434 HydrophobicContact SD-CE1 4.37Å; M292-F434 HydrophobicContact SD-CG 3.8Å
293	F	97.6	Very high	94.1	Very high	96 Å²	96	27.2 Å²	27.2	42%	0.421	15%	0.146	S	C	.	.	H	α-helix	trans	-68.1	-45.7	173.3	173.4	-98.7	0	0	0	111.8	A289 V290 G291 V295 M296 C297 L431	A289-F293 PolarHBondContact O-N 3.26Å; V290-F293 WeakPolarHBondContact O-CB 3.18Å; V290-F293 PolarHBondContact O-N 2.97Å; G291-F293 PolarHBondContact O-N 3.43Å; F293-V295 PolarHBondContact O-N 3.31Å; F293-M296 HydrophobicContact CD2-CE 3.64Å; F293-M296 HydrophobicContact CE2-CE 3.74Å; F293-M296 WeakPolarHBondContact O-CB 3.43Å; F293-M296 PolarHBondContact O-N 3.45Å; F293-C297 VanDerWaalsContact CZ-SG 3.56Å; F293-C297 PolarHBondContact O-N 3.36Å; F293-C297 PolarHBondContact O-SG 3.42Å; F293-C297 VanDerWaalsContact O-SG 3.4Å; F293-L431 HydrophobicContact CB-CD2 3.88Å; F293-L431 HydrophobicContact CD2-CD2 4.05Å; F293-L431 HydrophobicContact CG-CD2 4.49Å
294	F	97.7	Very high	94.8	Very high	53 Å²	53	30 Å²	30	23%	0.232	16%	0.157	C	C	.	.	H	α-helix	trans	-65.5	-36.6	179.4	-77.2	-66.5	0	0	0	113.2	V290 G291 M296 C297 S298 L344 I347	V290-F294 HydrophobicContact CG1-CD2 3.77Å; V290-F294 HydrophobicContact CG1-CE2 3.51Å; V290-F294 WeakPolarHBondContact O-CD2 3.24Å; V290-F294 PolarHBondContact O-N 3.26Å; V290-F294 VanDerWaalsContact O-N 3.11Å; G291-F294 PolarHBondContact O-N 3.03Å; G291-F294 VanDerWaalsContact O-N 3.1Å; F294-M296 VanDerWaalsContact C-N 3.31Å; F294-M296 PolarHBondContact O-N 3.22Å; F294-C297 PolarHBondContact O-N 2.95Å; F294-S298 PolarHBondContact O-N 3.19Å; F294-L344 HydrophobicContact CD1-CD2 3.68Å; F294-L344 HydrophobicContact CE1-CD2 4.23Å; F294-I347 HydrophobicContact CB-CG2 4.44Å; F294-I347 HydrophobicContact CD1-CG2 4.13Å; F294-I347 HydrophobicContact CD2-CG2 3.55Å; F294-I347 HydrophobicContact CE1-CG2 4.25Å; F294-I347 HydrophobicContact CE2-CG2 3.68Å; F294-I347 HydrophobicContact CG-CB 4.47Å; F294-I347 HydrophobicContact CG-CG2 3.79Å; F294-I347 HydrophobicContact CZ-CG2 4.04Å
295	V	97.6	Very high	95.4	Very high	0 Å²	0	28.5 Å²	28.5	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-67.4	-34.8	175.2	89.3	0	0	0	0	111.5	Y210 V213 G291 F293 S298 A299 I345 S348 Q427	Y210-V295 HydrophobicContact CD2-CB 4.17Å; Y210-V295 HydrophobicContact CD2-CG1 3.79Å; Y210-V295 HydrophobicContact CE2-CB 4.15Å; Y210-V295 HydrophobicContact CE2-CG1 4.29Å; Y210-V295 HydrophobicContact CE2-CG2 4.36Å; V213-V295 HydrophobicContact CB-CG1 4.34Å; V213-V295 HydrophobicContact CB-CG2 3.94Å; V213-V295 HydrophobicContact CG1-CG1 4.49Å; V213-V295 HydrophobicContact CG1-CG2 3.74Å; G291-V295 PolarHBondContact O-N 3.42Å; F293-V295 PolarHBondContact O-N 3.31Å; V295-S298 WeakPolarHBondContact O-CB 3.43Å; V295-S298 PolarHBondContact O-N 3.02Å; V295-A299 PolarHBondContact O-N 3.47Å; V295-A299 VanDerWaalsContact O-N 3.09Å; V295-I345 HydrophobicContact CG2-CG1 4.49Å; V295-S348 WeakPolarHBondContact CB-OG 3.24Å; V295-S348 PolarHBondContact N-OG 3.36Å; V295-Q427 HydrophobicContact CG1-CG 3.59Å
296	M	98	Very high	95.8	Very high	38 Å²	38	28 Å²	28	19%	0.187	14%	0.144	C	C	.	.	H	α-helix	trans	-62.4	-48.2	172.6	-179.9	-166.3	72.7	0	0	110.5	M292 F293 F294 S298 A299 V300 A424 Q427	M292-M296 PolarHBondContact O-N 2.96Å; F293-M296 HydrophobicContact CD2-CE 3.64Å; F293-M296 HydrophobicContact CE2-CE 3.74Å; F293-M296 WeakPolarHBondContact O-CB 3.43Å; F293-M296 PolarHBondContact O-N 3.45Å; F294-M296 VanDerWaalsContact C-N 3.31Å; F294-M296 PolarHBondContact O-N 3.22Å; M296-S298 VanDerWaalsContact C-N 3.27Å; M296-S298 PolarHBondContact O-N 3.4Å; M296-A299 PolarHBondContact O-N 3.25Å; M296-A299 VanDerWaalsContact O-N 3.16Å; M296-V300 WeakPolarHBondContact O-CG2 3.26Å; M296-V300 PolarHBondContact O-N 3.4Å; M296-A424 HydrophobicContact CG-CB 4.49Å; M296-Q427 HydrophobicContact CB-CB 4.31Å; M296-Q427 HydrophobicContact CB-CG 3.81Å
297	C	98.3	Very high	96.2	Very high	32 Å²	32	26 Å²	26	22%	0.216	14%	0.14	C	C	.	.	H	α-helix	trans	-59.8	-37.2	176.2	-67.9	0	0	0	0	112.2	F293 F294 V300 A301 L344	F293-C297 VanDerWaalsContact CZ-SG 3.56Å; F293-C297 PolarHBondContact O-N 3.36Å; F293-C297 PolarHBondContact O-SG 3.42Å; F293-C297 VanDerWaalsContact O-SG 3.4Å; F294-C297 PolarHBondContact O-N 2.95Å; C297-V300 PolarHBondContact O-N 2.87Å; C297-A301 WeakPolarHBondContact O-CB 3.18Å; C297-A301 PolarHBondContact O-N 3.22Å; C297-L344 HydrophobicContact CB-CD1 4.05Å; C297-L344 HydrophobicContact CB-CD2 4.29Å
298	S	97.1	Very high	96.4	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-60.1	-47.9	173.4	178.8	0	0	0	0	111.9	Y221 F294 V295 M296 V300 A301 A302 Q341 I345	Y221-S298 PolarHBondContact OH-O 3.4Å; Y221-S298 PolarHBondContact OH-OG 3.23Å; F294-S298 PolarHBondContact O-N 3.19Å; V295-S298 WeakPolarHBondContact O-CB 3.43Å; V295-S298 PolarHBondContact O-N 3.02Å; M296-S298 VanDerWaalsContact C-N 3.27Å; M296-S298 PolarHBondContact O-N 3.4Å; S298-V300 VanDerWaalsContact C-N 3.3Å; S298-V300 PolarHBondContact O-N 2.91Å; S298-A301 PolarHBondContact O-N 3.34Å; S298-A302 PolarHBondContact O-N 3.32Å; S298-Q341 PolarHBondContact OG-O 3.03Å; S298-I345 WeakPolarHBondContact OG-CG1 3.23Å
299	A	97.4	Very high	96.5	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-61.9	-38.9	178.1	0	0	0	0	0	112.1	V213 V295 M296 A302 G303 L423 A424	V213-A299 HydrophobicContact CG1-CB 3.85Å; V295-A299 PolarHBondContact O-N 3.47Å; V295-A299 VanDerWaalsContact O-N 3.09Å; M296-A299 PolarHBondContact O-N 3.25Å; M296-A299 VanDerWaalsContact O-N 3.16Å; A299-A302 PolarHBondContact O-N 2.99Å; A299-G303 PolarHBondContact O-N 3.29Å; A299-L423 HydrophobicContact CB-CB 4.47Å; A299-A424 HydrophobicContact CB-CB 3.86Å
300	V	98.3	Very high	96.5	Very high	51 Å²	51	29.8 Å²	29.8	31%	0.309	16%	0.157	S	C	.	.	H	α-helix	trans	-62.6	-46.4	172.7	174.4	0	0	0	0	111.2	M296 C297 S298 A302 G303 I304 F421 A424	M296-V300 WeakPolarHBondContact O-CG2 3.26Å; M296-V300 PolarHBondContact O-N 3.4Å; C297-V300 PolarHBondContact O-N 2.87Å; S298-V300 VanDerWaalsContact C-N 3.3Å; S298-V300 PolarHBondContact O-N 2.91Å; V300-A302 VanDerWaalsContact C-N 3.32Å; V300-A302 PolarHBondContact O-N 3.49Å; V300-G303 PolarHBondContact O-N 3.32Å; V300-I304 HydrophobicContact CG1-CD1 3.83Å; V300-I304 HydrophobicContact CG1-CG1 4.4Å; V300-I304 WeakPolarHBondContact O-CG1 3.34Å; V300-I304 PolarHBondContact O-N 3.15Å; V300-F421 HydrophobicContact CG1-CE1 4.47Å; V300-A424 HydrophobicContact CG2-CB 3.63Å
301	A	97.4	Very high	96.5	Very high	23 Å²	23	32 Å²	32	19%	0.19	16%	0.163	C	C	.	.	H	α-helix	trans	-59.4	-43.1	177.8	0	0	0	0	0	111.6	C297 S298 G303 I304 L305 Q341 L344	C297-A301 WeakPolarHBondContact O-CB 3.18Å; C297-A301 PolarHBondContact O-N 3.22Å; S298-A301 PolarHBondContact O-N 3.34Å; A301-G303 PolarHBondContact O-N 3.48Å; A301-I304 PolarHBondContact O-N 3.24Å; A301-L305 WeakPolarHBondContact O-CB 3.21Å; A301-L305 PolarHBondContact O-N 2.94Å; A301-Q341 HydrophobicContact CB-CB 4.29Å; A301-L344 HydrophobicContact CB-CD1 4.25Å
302	A	96.1	Very high	96.4	Very high	0 Å²	0	33.7 Å²	33.7	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-62.7	-40	175.3	0	0	0	0	0	112.8	Y221 Q224 S298 A299 V300 L305 E306 Q341 F420	Y221-A302 HydrophobicContact CD1-CB 4.45Å; Y221-A302 HydrophobicContact CE1-CB 3.66Å; Q224-A302 PolarHBondContact NE2-O 2.89Å; S298-A302 PolarHBondContact O-N 3.32Å; A299-A302 PolarHBondContact O-N 2.99Å; V300-A302 VanDerWaalsContact C-N 3.32Å; V300-A302 PolarHBondContact O-N 3.49Å; A302-L305 PolarHBondContact O-N 3.11Å; A302-E306 WeakPolarHBondContact O-CB 3.5Å; A302-E306 PolarHBondContact O-N 3.11Å; A302-Q341 HydrophobicContact CB-CB 4.5Å; A302-Q341 VanDerWaalsContact CB-OE1 3.29Å; A302-F420 HydrophobicContact CB-CB 4.46Å; A302-F420 HydrophobicContact CB-CD1 4.24Å; A302-F420 HydrophobicContact CB-CD2 3.89Å; A302-F420 HydrophobicContact CB-CE1 4.46Å; A302-F420 HydrophobicContact CB-CE2 4.11Å; A302-F420 HydrophobicContact CB-CG 3.96Å; A302-F420 HydrophobicContact CB-CZ 4.39Å; A302-F420 WeakPolarHBondContact O-CD2 3.47Å
303	G	96.6	Very high	96.2	Very high	0 Å²	0	34.6 Å²	34.6	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-63.9	-42.9	174.2	0	0	0	0	0	113.3	A299 V300 A301 E306 T307	A299-G303 PolarHBondContact O-N 3.29Å; V300-G303 PolarHBondContact O-N 3.32Å; A301-G303 PolarHBondContact O-N 3.48Å; G303-E306 PolarHBondContact O-N 3.03Å; G303-T307 PolarHBondContact O-N 2.9Å; G303-T307 PolarHBondContact O-OG1 2.82Å
304	I	97.4	Very high	95.8	Very high	94 Å²	94	38.4 Å²	38.4	48%	0.482	19%	0.194	S	C	.	.	H	α-helix	trans	-63.8	-46.8	176.5	-67.4	167.6	0	0	0	110.4	V300 A301 E306 T307 K308 F421	V300-I304 HydrophobicContact CG1-CD1 3.83Å; V300-I304 HydrophobicContact CG1-CG1 4.4Å; V300-I304 WeakPolarHBondContact O-CG1 3.34Å; V300-I304 PolarHBondContact O-N 3.15Å; A301-I304 PolarHBondContact O-N 3.24Å; I304-E306 VanDerWaalsContact C-N 3.31Å; I304-E306 PolarHBondContact O-N 2.76Å; I304-T307 WeakPolarHBondContact O-CB 3.18Å; I304-T307 PolarHBondContact O-N 3.19Å; I304-K308 PolarHBondContact O-N 2.96Å; I304-F421 HydrophobicContact CG1-CE1 4.46Å; I304-F421 HydrophobicContact CG1-CZ 4.3Å
305	L	96.3	Very high	95.6	Very high	10 Å²	10	39.7 Å²	39.7	5%	0.052	21%	0.21	C	C	.	.	H	α-helix	trans	-58.3	-45.4	176.9	178.1	55.4	0	0	0	111.4	L228 A301 A302 T307 K308 R309 L333 W337 Q338	L228-L305 HydrophobicContact CD1-CD2 4.24Å; A301-L305 WeakPolarHBondContact O-CB 3.21Å; A301-L305 PolarHBondContact O-N 2.94Å; A302-L305 PolarHBondContact O-N 3.11Å; L305-T307 VanDerWaalsContact C-N 3.31Å; L305-T307 PolarHBondContact O-N 2.81Å; L305-K308 PolarHBondContact O-N 3.02Å; L305-R309 WeakPolarHBondContact O-CB 3.36Å; L305-R309 PolarHBondContact O-N 3.46Å; L305-L333 HydrophobicContact CD1-CD2 3.54Å; L305-W337 HydrophobicContact CD1-CB 3.58Å; L305-W337 HydrophobicContact CD1-CG 4.42Å; L305-W337 HydrophobicContact CD2-CB 4.41Å; L305-Q338 HydrophobicContact CD2-CB 4.32Å; L305-Q338 HydrophobicContact CD2-CG 3.45Å; L305-Q338 VanDerWaalsContact CD2-CG 3.45Å
306	E	95.7	Very high	95.3	Very high	0 Å²	0	45.7 Å²	45.7	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-66	-36.4	179.8	-171.3	56.4	-160.6	0	0	112.4	Q224 A302 G303 I304 K308 R309 L310 L416 H417 F420	Q224-E306 WeakPolarHBondContact CG-OE2 3.45Å; Q224-E306 PolarHBondContact NE2-OE2 3.45Å; A302-E306 WeakPolarHBondContact O-CB 3.5Å; A302-E306 PolarHBondContact O-N 3.11Å; G303-E306 PolarHBondContact O-N 3.03Å; I304-E306 VanDerWaalsContact C-N 3.31Å; I304-E306 PolarHBondContact O-N 2.76Å; E306-K308 VanDerWaalsContact C-N 3.34Å; E306-K308 PolarHBondContact O-N 3.14Å; E306-R309 VanDerWaalsContact CD-NE 3.3Å; E306-R309 PolarHBondContact O-N 3.34Å; E306-R309 IonicContact OE1-CZ 3.47Å; E306-R309 VanDerWaalsContact OE1-CZ 3.26Å; E306-R309 IonicContact OE1-NE 3.28Å; E306-R309 PolarHBondContact OE1-NE 3.45Å; E306-R309 IonicContact OE1-NH2 3.04Å; E306-R309 PolarHBondContact OE1-NH2 3.48Å; E306-R309 IonicContact OE2-NE 3.87Å; E306-R309 PolarHBondContact OE2-NE 2.89Å; E306-L310 HydrophobicContact CG-CD1 4.13Å; E306-L310 WeakPolarHBondContact O-CB 3.27Å; E306-L310 WeakPolarHBondContact O-CG 3.45Å; E306-L310 PolarHBondContact O-N 3.4Å; E306-L416 HydrophobicContact CG-CB 3.88Å; E306-L416 HydrophobicContact CG-CD2 4.36Å; E306-L416 HydrophobicContact CG-CG 4.16Å; E306-H417 HydrophobicContact CB-CB 3.91Å; E306-H417 HydrophobicContact CG-CB 3.92Å; E306-F420 HydrophobicContact CB-CD2 4.1Å; E306-F420 HydrophobicContact CB-CE2 4.17Å; E306-F420 HydrophobicContact CG-CE2 4.44Å
307	T	95.7	Very high	94.8	Very high	56 Å²	56	45.5 Å²	45.5	34%	0.344	25%	0.249	S	C	.	.	H	α-helix	trans	-60.6	-46.3	174.2	-55.6	0	0	0	0	110.5	G303 I304 L305 L310 E311	G303-T307 PolarHBondContact O-N 2.9Å; G303-T307 PolarHBondContact O-OG1 2.82Å; I304-T307 WeakPolarHBondContact O-CB 3.18Å; I304-T307 PolarHBondContact O-N 3.19Å; L305-T307 VanDerWaalsContact C-N 3.31Å; L305-T307 PolarHBondContact O-N 2.81Å; T307-L310 PolarHBondContact O-N 2.86Å; T307-E311 PolarHBondContact O-N 3.49Å
308	K	95.1	Very high	94.4	Very high	107 Å²	107	47 Å²	47	47%	0.465	26%	0.257	S	S	.	.	H	α-helix	trans	-66.7	-40.5	178.5	-74.2	-72.7	159	-158.1	0	112.7	I304 L305 E306 E311 I312	I304-K308 PolarHBondContact O-N 2.96Å; L305-K308 PolarHBondContact O-N 3.02Å; E306-K308 VanDerWaalsContact C-N 3.34Å; E306-K308 PolarHBondContact O-N 3.14Å; K308-E311 IonicContact NZ-OE1 3.95Å; K308-E311 IonicContact NZ-OE2 2.74Å; K308-E311 PolarHBondContact NZ-OE2 3.34Å; K308-E311 WeakPolarHBondContact O-CB 3.47Å; K308-E311 PolarHBondContact O-N 3.1Å; K308-I312 WeakPolarHBondContact O-CG1 3.23Å; K308-I312 PolarHBondContact O-N 3.08Å; K308-I312 VanDerWaalsContact O-N 3.11Å
309	R	95.1	Very high	93.9	Very high	0 Å²	0	50.3 Å²	50.3	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-59.2	-48.1	175.5	-168.6	-161.4	70.7	72.6	0.9	111.2	L228 L305 E306 E311 I312 V313 A331 L333 I411 N412	L228-R309 HydrophobicContact CD2-CB 4.49Å; L228-R309 HydrophobicContact CD2-CG 3.93Å; L305-R309 WeakPolarHBondContact O-CB 3.36Å; L305-R309 PolarHBondContact O-N 3.46Å; E306-R309 VanDerWaalsContact CD-NE 3.3Å; E306-R309 PolarHBondContact O-N 3.34Å; E306-R309 IonicContact OE1-CZ 3.47Å; E306-R309 VanDerWaalsContact OE1-CZ 3.26Å; E306-R309 IonicContact OE1-NE 3.28Å; E306-R309 PolarHBondContact OE1-NE 3.45Å; E306-R309 IonicContact OE1-NH2 3.04Å; E306-R309 PolarHBondContact OE1-NH2 3.48Å; E306-R309 IonicContact OE2-NE 3.87Å; E306-R309 PolarHBondContact OE2-NE 2.89Å; R309-E311 VanDerWaalsContact C-N 3.33Å; R309-E311 PolarHBondContact O-N 3.07Å; R309-I312 PolarHBondContact O-N 3.49Å; R309-V313 WeakPolarHBondContact O-CG2 3.41Å; R309-V313 PolarHBondContact O-N 3.4Å; R309-A331 HydrophobicContact CG-CB 3.57Å; R309-L333 HydrophobicContact CB-CD2 4.27Å; R309-I411 PolarHBondContact NH2-O 3.16Å; R309-N412 PolarHBondContact NH1-OD1 3.17Å
310	L	93.2	Very high	93.3	Very high	9 Å²	9	53.8 Å²	53.8	5%	0.047	29%	0.293	C	S	.	.	H	α-helix	trans	-66.1	-33.4	178.9	-73.7	167.2	0	0	0	113	E306 T307 V313 K314 H417	E306-L310 HydrophobicContact CG-CD1 4.13Å; E306-L310 WeakPolarHBondContact O-CB 3.27Å; E306-L310 WeakPolarHBondContact O-CG 3.45Å; E306-L310 PolarHBondContact O-N 3.4Å; T307-L310 PolarHBondContact O-N 2.86Å; L310-V313 PolarHBondContact O-N 2.86Å; L310-K314 WeakPolarHBondContact O-CG 3.31Å; L310-K314 PolarHBondContact O-N 3.07Å; L310-K314 VanDerWaalsContact O-N 3.13Å; L310-H417 WeakPolarHBondContact CD1-ND1 3.24Å
311	E	94	Very high	92.5	Very high	102 Å²	102	51.7 Å²	51.7	48%	0.477	28%	0.28	S	S	.	.	H	α-helix	trans	-61.7	-47.7	173.4	-172	178.4	-174.8	0	0	110.9	T307 K308 R309 V313 K314 S315	T307-E311 PolarHBondContact O-N 3.49Å; K308-E311 IonicContact NZ-OE1 3.95Å; K308-E311 IonicContact NZ-OE2 2.74Å; K308-E311 PolarHBondContact NZ-OE2 3.34Å; K308-E311 WeakPolarHBondContact O-CB 3.47Å; K308-E311 PolarHBondContact O-N 3.1Å; R309-E311 VanDerWaalsContact C-N 3.33Å; R309-E311 PolarHBondContact O-N 3.07Å; E311-V313 PolarHBondContact O-N 2.89Å; E311-K314 PolarHBondContact O-N 3.44Å; E311-S315 PolarHBondContact O-N 3.45Å; E311-S315 PolarHBondContact O-OG 3.46Å
312	I	93.2	Very high	91.5	Very high	36 Å²	36	51.4 Å²	51.4	19%	0.185	28%	0.276	C	S	.	.	H	α-helix	trans	-62.8	-42.3	177.6	-66.7	166.4	0	0	0	111.3	K308 R309 K314 S315 N316 A331 L333	K308-I312 WeakPolarHBondContact O-CG1 3.23Å; K308-I312 PolarHBondContact O-N 3.08Å; K308-I312 VanDerWaalsContact O-N 3.11Å; R309-I312 PolarHBondContact O-N 3.49Å; I312-K314 VanDerWaalsContact C-N 3.26Å; I312-K314 PolarHBondContact O-N 2.85Å; I312-S315 PolarHBondContact O-N 3.15Å; I312-S315 PolarHBondContact O-OG 2.83Å; I312-N316 HydrophobicContact CG2-CB 4.31Å; I312-N316 WeakPolarHBondContact O-CA 3.43Å; I312-N316 WeakPolarHBondContact O-CB 3.17Å; I312-N316 PolarHBondContact O-N 2.87Å; I312-A331 HydrophobicContact CB-CB 4.5Å; I312-A331 HydrophobicContact CG2-CB 4.23Å; I312-L333 HydrophobicContact CD1-CB 4.01Å; I312-L333 HydrophobicContact CD1-CD1 3.86Å; I312-L333 HydrophobicContact CD1-CD2 4.35Å; I312-L333 HydrophobicContact CD1-CG 4.3Å
313	V	91.9	Very high	90.3	Very high	20 Å²	20	52.6 Å²	52.6	12%	0.121	28%	0.282	C	S	.	.	H	α-helix	trans	-60.2	-38.6	177.2	169.5	0	0	0	0	111.6	R309 L310 E311 G317 T318 A331 N412	R309-V313 WeakPolarHBondContact O-CG2 3.41Å; R309-V313 PolarHBondContact O-N 3.4Å; L310-V313 PolarHBondContact O-N 2.86Å; E311-V313 PolarHBondContact O-N 2.89Å; V313-G317 VanDerWaalsContact O-CA 3.26Å; V313-G317 WeakPolarHBondContact O-CA 3.45Å; V313-G317 PolarHBondContact O-N 3.03Å; V313-T318 HydrophobicContact CG1-CG2 3.82Å; V313-T318 HydrophobicContact CG2-CG2 4.29Å; V313-A331 HydrophobicContact CG2-CB 3.76Å; V313-N412 HydrophobicContact CG1-CB 4.07Å
314	K	90.5	Very high	89	Confident	175 Å²	175	55.4 Å²	55.4	76%	0.761	31%	0.311	S	S	*	.	H	α-helix	trans	-74.5	-33.7	178.9	-71.7	173	-178.3	178.2	0	112.9	L310 E311 I312	L310-K314 WeakPolarHBondContact O-CG 3.31Å; L310-K314 PolarHBondContact O-N 3.07Å; L310-K314 VanDerWaalsContact O-N 3.13Å; E311-K314 PolarHBondContact O-N 3.44Å; I312-K314 VanDerWaalsContact C-N 3.26Å; I312-K314 PolarHBondContact O-N 2.85Å
315	S	92.9	Very high	87.5	Confident	81 Å²	81	59.7 Å²	59.7	57%	0.566	33%	0.326	S	S	*	.	H	α-helix	trans	-88.6	-43.3	-176.2	68.4	0	0	0	0	113.5	E311 I312	E311-S315 PolarHBondContact O-N 3.45Å; E311-S315 PolarHBondContact O-OG 3.46Å; I312-S315 PolarHBondContact O-N 3.15Å; I312-S315 PolarHBondContact O-OG 2.83Å
316	N	90.7	Very high	86.2	Confident	126 Å²	126	60.3 Å²	60.3	67%	0.674	33%	0.33	S	S	*	.	H	α-helix	trans	-113.4	-4.3	-169.3	-63.3	18.7	0	0	0	112.6	I312	I312-N316 HydrophobicContact CG2-CB 4.31Å; I312-N316 WeakPolarHBondContact O-CA 3.43Å; I312-N316 WeakPolarHBondContact O-CB 3.17Å; I312-N316 PolarHBondContact O-N 2.87Å
317	G	88.3	Confident	85.3	Confident	33 Å²	33	62.7 Å²	62.7	34%	0.34	35%	0.345	S	S	.	.			trans	78.1	-160.4	-176.7	0	0	0	0	0	113.4	V313	V313-G317 VanDerWaalsContact O-CA 3.26Å; V313-G317 WeakPolarHBondContact O-CA 3.45Å; V313-G317 PolarHBondContact O-N 3.03Å
318	T	89.7	Confident	84.6	Confident	64 Å²	64	60.6 Å²	60.6	39%	0.393	33%	0.331	S	S	.	.			trans	-117.8	152.8	-175.7	56	0	0	0	0	112	V313 H329 A330 N412	V313-T318 HydrophobicContact CG1-CG2 3.82Å; V313-T318 HydrophobicContact CG2-CG2 4.29Å; T318-H329 HydrophobicContact CG2-CB 4.19Å; T318-A330 CarbonylContact C-O 3.56Å; T318-A330 VanDerWaalsContact CA-O 3.27Å; T318-A330 WeakPolarHBondContact CA-O 3.48Å; T318-N412 WeakPolarHBondContact CG2-ND2 3.46Å
319	I	86.6	Confident	84.1	Confident	69 Å²	69	58.3 Å²	58.3	35%	0.354	32%	0.322	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.2	128.9	171.3	-59.8	177.2	0	0	0	108.1	Q321 A330 D332	I319-Q321 PolarHBondContact O-N 2.99Å; I319-A330 PolarHBondContact N-O 2.99Å; I319-A330 PolarHBondContact O-N 3.04Å; I319-D332 HydrophobicContact CD1-CB 3.51Å; I319-D332 HydrophobicContact CG1-CB 4.42Å
320	D	84.9	Confident	83.7	Confident	74 Å²	74	58.3 Å²	58.3	40%	0.396	32%	0.322	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-74.8	125.5	174.3	-67.5	-13.8	0	0	0	109.9	V327 H329	D320-V327 HydrophobicContact CB-CG1 4.06Å; D320-H329 IonicContact OD1-CE1 2.73Å; D320-H329 PolarHBondContact OD1-CE1 3.42Å; D320-H329 IonicContact OD1-CG 3.75Å; D320-H329 IonicContact OD1-ND1 3.72Å; D320-H329 PolarHBondContact OD1-ND1 2.95Å
321	Q	80.8	Confident	83.6	Confident	7 Å²	7	57.9 Å²	57.9	3%	0.033	32%	0.32	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.9	136.2	172.7	67.8	175.5	-20.7	0	0	111	F226 L228 T233 I319 L323 F328 A330	F226-Q321 PolarHBondContact O-NE2 3.36Å; L228-Q321 PolarHBondContact O-NE2 3.19Å; L228-Q321 PolarHBondContact O-OE1 3.02Å; T233-Q321 PolarHBondContact OG1-OE1 3.03Å; I319-Q321 PolarHBondContact O-N 2.99Å; Q321-L323 HydrophobicContact CG-CD1 4.38Å; Q321-F328 HydrophobicContact CG-CB 4.01Å; Q321-F328 PolarHBondContact N-O 3.33Å; Q321-F328 PolarHBondContact O-N 2.91Å; Q321-A330 HydrophobicContact CG-CB 4.05Å; Q321-A330 VanDerWaalsContact NE2-CB 3.34Å
322	V	76.1	Confident	83.5	Confident	16 Å²	16	56.6 Å²	56.6	10%	0.097	32%	0.316	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.8	120.7	178.7	-172.4	0	0	0	0	109.8	T233 P234 I237 V326 V327	T233-V322 WeakPolarHBondContact CG2-O 3.33Å; P234-V322 PolarHBondContact O-N 3.42Å; I237-V322 HydrophobicContact CG1-CG1 4.26Å; I237-V322 HydrophobicContact CG1-CG2 3.82Å; V322-V326 WeakPolarHBondContact CA-O 3.49Å; V322-V327 HydrophobicContact CG2-CG2 4.39Å
323	L	72.1	Confident	83.3	Confident	25 Å²	25	55.7 Å²	55.7	13%	0.131	31%	0.312	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-117.4	109.9	174	-78.8	151.6	0	0	0	108.8	F226 I230 T233 Q321 K325 V326 F328	F226-L323 HydrophobicContact CB-CD1 4.46Å; F226-L323 HydrophobicContact CD1-CD1 3.79Å; F226-L323 HydrophobicContact CE1-CD1 4.49Å; I230-L323 HydrophobicContact CD1-CD1 4.15Å; I230-L323 HydrophobicContact CD1-CD2 3.96Å; T233-L323 HydrophobicContact CG2-CD2 4.31Å; T233-L323 HydrophobicContact CG2-CG 4.49Å; Q321-L323 HydrophobicContact CG-CD1 4.38Å; L323-K325 PolarHBondContact O-N 3.34Å; L323-V326 PolarHBondContact N-O 3.08Å; L323-V326 PolarHBondContact O-N 3.44Å; L323-F328 HydrophobicContact CB-CD2 3.9Å; L323-F328 HydrophobicContact CB-CE2 3.87Å; L323-F328 HydrophobicContact CD1-CD2 3.62Å; L323-F328 HydrophobicContact CD1-CE2 4.02Å; L323-F328 HydrophobicContact CD1-CG 4.29Å; L323-F328 HydrophobicContact CG-CD2 4.34Å
324	G	68.5	Low	83.2	Confident	60 Å²	60	57.3 Å²	57.3	62%	0.619	32%	0.322	S	S	*	.	T	Hydrogen-bonded Turn	trans	61.4	-108.1	-170.4	0	0	0	0	0	110.9
325	K	65.6	Low	83.1	Confident	184 Å²	184	49.2 Å²	49.2	80%	0.8	29%	0.287	S	S	*	.	T	Hydrogen-bonded Turn	trans	-113	9.9	178.3	-63.7	-177.2	-179.4	-179.7	0	113.2	R38 L323	R38-K325 VanDerWaalsContact NH2-CB 3.31Å; R38-K325 PolarHBondContact NH2-O 3.05Å; L323-K325 PolarHBondContact O-N 3.34Å
326	V	70.1	Confident	82.9	Confident	23 Å²	23	52.9 Å²	52.9	14%	0.139	29%	0.289	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.6	136.6	-171.8	-174.7	0	0	0	0	108.9	P18 V322 L323 F328	P18-V326 HydrophobicContact CB-CG1 4.01Å; P18-V326 HydrophobicContact CG-CG1 3.86Å; P18-V326 HydrophobicContact CG-CG2 3.83Å; V322-V326 WeakPolarHBondContact CA-O 3.49Å; L323-V326 PolarHBondContact N-O 3.08Å; L323-V326 PolarHBondContact O-N 3.44Å; V326-F328 HydrophobicContact CB-CD2 4.32Å; V326-F328 HydrophobicContact CB-CE2 3.77Å; V326-F328 HydrophobicContact CB-CZ 4.41Å; V326-F328 HydrophobicContact CG1-CD2 4.02Å; V326-F328 HydrophobicContact CG1-CE2 3.57Å; V326-F328 HydrophobicContact CG1-CZ 3.87Å
327	V	76.1	Confident	82.9	Confident	49 Å²	49	54.4 Å²	54.4	30%	0.297	29%	0.285	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.2	128.4	171.3	-174.4	0	0	0	0	108.5	I237 D320 V322	I237-V327 HydrophobicContact CD1-CG2 3.91Å; I237-V327 HydrophobicContact CG1-CG2 4.48Å; D320-V327 HydrophobicContact CB-CG1 4.06Å; V322-V327 HydrophobicContact CG2-CG2 4.39Å
328	F	80.5	Confident	83	Confident	13 Å²	13	53 Å²	53	6%	0.057	27%	0.27	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.1	139.4	172.3	-70.7	-90.3	0	0	0	109.7	P18 V19 F226 Q321 L323 V326 A330	P18-F328 HydrophobicContact CB-CE1 4.36Å; P18-F328 HydrophobicContact CB-CZ 4.12Å; V19-F328 HydrophobicContact CG2-CD1 4.08Å; V19-F328 HydrophobicContact CG2-CE1 4.24Å; F226-F328 HydrophobicContact CB-CD1 3.98Å; F226-F328 HydrophobicContact CB-CE1 3.99Å; F226-F328 HydrophobicContact CB-CG 4.39Å; F226-F328 HydrophobicContact CB-CZ 4.39Å; F226-F328 HydrophobicContact CD2-CE1 4.36Å; F226-F328 HydrophobicContact CD2-CZ 4.34Å; F226-F328 HydrophobicContact CG-CE1 4.35Å; F226-F328 HydrophobicContact CG-CZ 4.35Å; F226-F328 WeakPolarHBondContact O-CB 3.47Å; Q321-F328 HydrophobicContact CG-CB 4.01Å; Q321-F328 PolarHBondContact N-O 3.33Å; Q321-F328 PolarHBondContact O-N 2.91Å; L323-F328 HydrophobicContact CB-CD2 3.9Å; L323-F328 HydrophobicContact CB-CE2 3.87Å; L323-F328 HydrophobicContact CD1-CD2 3.62Å; L323-F328 HydrophobicContact CD1-CE2 4.02Å; L323-F328 HydrophobicContact CD1-CG 4.29Å; L323-F328 HydrophobicContact CG-CD2 4.34Å; V326-F328 HydrophobicContact CB-CD2 4.32Å; V326-F328 HydrophobicContact CB-CE2 3.77Å; V326-F328 HydrophobicContact CB-CZ 4.41Å; V326-F328 HydrophobicContact CG1-CD2 4.02Å; V326-F328 HydrophobicContact CG1-CE2 3.57Å; V326-F328 HydrophobicContact CG1-CZ 3.87Å; F328-A330 PolarHBondContact O-N 3.15Å
329	H	86	Confident	83	Confident	58 Å²	58	52.6 Å²	52.6	27%	0.269	27%	0.267	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-93	95.8	177.2	-57.4	-61.3	0	0	0	109.4	H227 T318 D320 N412	H227-H329 PolarHBondContact CD2-O 3.47Å; T318-H329 HydrophobicContact CG2-CB 4.19Å; D320-H329 IonicContact OD1-CE1 2.73Å; D320-H329 PolarHBondContact OD1-CE1 3.42Å; D320-H329 IonicContact OD1-CG 3.75Å; D320-H329 IonicContact OD1-ND1 3.72Å; D320-H329 PolarHBondContact OD1-ND1 2.95Å; H329-N412 PolarHBondContact O-ND2 3.11Å
330	A	87.1	Confident	83.3	Confident	1 Å²	1	52.5 Å²	52.5	1%	0.008	27%	0.271	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.6	159.5	-173.1	0	0	0	0	0	112.9	H227 T318 I319 Q321 F328	H227-A330 WeakPolarHBondContact O-CA 3.5Å; T318-A330 CarbonylContact C-O 3.56Å; T318-A330 VanDerWaalsContact CA-O 3.27Å; T318-A330 WeakPolarHBondContact CA-O 3.48Å; I319-A330 PolarHBondContact N-O 2.99Å; I319-A330 PolarHBondContact O-N 3.04Å; Q321-A330 HydrophobicContact CG-CB 4.05Å; Q321-A330 VanDerWaalsContact NE2-CB 3.34Å; F328-A330 PolarHBondContact O-N 3.15Å
331	A	91	Very high	83.7	Confident	0 Å²	0	49 Å²	49	0%	0	25%	0.252	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-81	152	164.4	0	0	0	0	0	110.4	H227 R229 R309 I312 V313 L333	H227-A331 PolarHBondContact O-N 3.35Å; R229-A331 PolarHBondContact N-O 3.23Å; R309-A331 HydrophobicContact CG-CB 3.57Å; I312-A331 HydrophobicContact CB-CB 4.5Å; I312-A331 HydrophobicContact CG2-CB 4.23Å; V313-A331 HydrophobicContact CG2-CB 3.76Å; A331-L333 HydrophobicContact CB-CB 4.34Å; A331-L333 PolarHBondContact O-N 3.27Å
332	D	90.2	Very high	84.1	Confident	75 Å²	75	48.9 Å²	48.9	40%	0.401	25%	0.252	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-74.5	58.5	169.1	-163.6	16.1	0	0	0	111.7	R229 I319	R229-D332 WeakPolarHBondContact CD-OD1 3.46Å; R229-D332 IonicContact CZ-OD1 2.84Å; R229-D332 IonicContact NE-OD1 2.72Å; R229-D332 IonicContact NH1-OD1 3.81Å; R229-D332 PolarHBondContact NH1-OD1 3.47Å; R229-D332 IonicContact NH1-OD2 2.83Å; I319-D332 HydrophobicContact CD1-CB 3.51Å; I319-D332 HydrophobicContact CG1-CB 4.42Å
333	L	90.8	Very high	84.9	Confident	17 Å²	17	50.2 Å²	50.2	9%	0.089	26%	0.259	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-129	118.3	179.1	-173.1	67.8	0	0	0	108.2	L228 R229 L305 R309 I312 A331 W337	L228-L333 HydrophobicContact CD2-CB 3.93Å; L228-L333 HydrophobicContact CD2-CD2 3.76Å; L228-L333 HydrophobicContact CD2-CG 4.04Å; R229-L333 PolarHBondContact N-O 3.02Å; L305-L333 HydrophobicContact CD1-CD2 3.54Å; R309-L333 HydrophobicContact CB-CD2 4.27Å; I312-L333 HydrophobicContact CD1-CB 4.01Å; I312-L333 HydrophobicContact CD1-CD1 3.86Å; I312-L333 HydrophobicContact CD1-CD2 4.35Å; I312-L333 HydrophobicContact CD1-CG 4.3Å; A331-L333 HydrophobicContact CB-CB 4.34Å; A331-L333 PolarHBondContact O-N 3.27Å; L333-W337 HydrophobicContact CD1-CG 4.2Å; L333-W337 HydrophobicContact CG-CG 4.41Å
334	P	90	Very high	86	Confident	53 Å²	53	50.8 Å²	50.8	34%	0.344	26%	0.262	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-64.2	142.2	-175	10.1	-13.1	0	0	0	111.9	W336 W337	P334-W336 PolarHBondContact O-N 3.2Å; P334-W337 PolarHBondContact O-N 3.41Å
335	I	88	Confident	87.1	Confident	5 Å²	5	47.9 Å²	47.9	3%	0.026	23%	0.233	C	C	.	.	G	3₁₀ helix	trans	-55.6	-24.4	179.6	-167.2	162.7	0	0	0	114.3	L228 R229 I230 L252 W337 Q338	L228-I335 HydrophobicContact CB-CB 4.41Å; R229-I335 PolarHBondContact O-N 2.9Å; I230-I335 HydrophobicContact CD1-CD1 4.36Å; I230-I335 HydrophobicContact CG1-CD1 4.01Å; L252-I335 HydrophobicContact CD1-CD1 3.73Å; L252-I335 HydrophobicContact CD2-CD1 3.77Å; L252-I335 HydrophobicContact CD2-CG1 4.23Å; L252-I335 HydrophobicContact CG-CD1 4.28Å; I335-W337 PolarHBondContact O-N 2.59Å; I335-Q338 WeakPolarHBondContact O-CB 3.37Å; I335-Q338 PolarHBondContact O-N 3.23Å
336	W	87.5	Confident	88.3	Confident	158 Å²	158	39.1 Å²	39.1	60%	0.598	20%	0.195	S	C	*	.	G	3₁₀ helix	trans	-57.5	-21.8	178.6	-53.8	121.4	0	0	0	114	P231 P334 Q338 V339	P231-W336 HydrophobicContact CG-CZ2 4.47Å; P334-W336 PolarHBondContact O-N 3.2Å; W336-Q338 PolarHBondContact O-N 3.1Å; W336-Q338 VanDerWaalsContact O-N 3.17Å; W336-V339 HydrophobicContact CE3-CG2 4.38Å; W336-V339 WeakPolarHBondContact O-CB 3.43Å; W336-V339 VanDerWaalsContact O-CG2 3.26Å; W336-V339 WeakPolarHBondContact O-CG2 3.4Å; W336-V339 PolarHBondContact O-N 3.06Å
337	W	91.2	Very high	89.4	Confident	159 Å²	159	39.9 Å²	39.9	60%	0.602	20%	0.198	S	C	*	.	G	3₁₀ helix	trans	-64.7	-12.6	172.8	-78.9	98.9	0	0	0	114.2	L305 L333 P334 I335 P340	L305-W337 HydrophobicContact CD1-CB 3.58Å; L305-W337 HydrophobicContact CD1-CG 4.42Å; L305-W337 HydrophobicContact CD2-CB 4.41Å; L333-W337 HydrophobicContact CD1-CG 4.2Å; L333-W337 HydrophobicContact CG-CG 4.41Å; P334-W337 PolarHBondContact O-N 3.41Å; I335-W337 PolarHBondContact O-N 2.59Å; W337-P340 WeakPolarHBondContact O-CD 3.34Å
338	Q	91	Very high	90.3	Very high	3 Å²	3	37.6 Å²	37.6	1%	0.014	18%	0.184	C	C	.	.	G	3₁₀ helix	trans	-82.4	-10.8	170.3	-70.5	-173.4	-44.8	0	0	114	Y221 Q224 S225 L228 L305 I335 W336 P340 Q341 Y342	Y221-Q338 PolarHBondContact O-NE2 3.23Å; Q224-Q338 VanDerWaalsContact OE1-NE2 3.09Å; S225-Q338 VanDerWaalsContact CB-OE1 3.26Å; S225-Q338 PolarHBondContact OG-NE2 2.98Å; S225-Q338 PolarHBondContact OG-OE1 3.14Å; L228-Q338 VanDerWaalsContact CD1-CD 3.5Å; L228-Q338 HydrophobicContact CD1-CG 3.46Å; L228-Q338 VanDerWaalsContact CD1-CG 3.46Å; L305-Q338 HydrophobicContact CD2-CB 4.32Å; L305-Q338 HydrophobicContact CD2-CG 3.45Å; L305-Q338 VanDerWaalsContact CD2-CG 3.45Å; I335-Q338 WeakPolarHBondContact O-CB 3.37Å; I335-Q338 PolarHBondContact O-N 3.23Å; W336-Q338 PolarHBondContact O-N 3.1Å; W336-Q338 VanDerWaalsContact O-N 3.17Å; Q338-P340 VanDerWaalsContact C-CD 3.45Å; Q338-P340 VanDerWaalsContact C-N 3.33Å; Q338-Q341 HydrophobicContact CB-CG 4.34Å; Q338-Q341 WeakPolarHBondContact O-CG 3.44Å; Q338-Q341 PolarHBondContact O-N 3.27Å; Q338-Y342 HydrophobicContact CB-CD2 4.22Å; Q338-Y342 HydrophobicContact CB-CE2 4.29Å; Q338-Y342 WeakPolarHBondContact O-CD2 3.09Å; Q338-Y342 PolarHBondContact O-N 3Å
339	V	89.5	Confident	90.9	Very high	56 Å²	56	38.4 Å²	38.4	34%	0.339	19%	0.188	S	C	.	.	H	α-helix	trans	-54.2	-44.1	-180	171.7	0	0	0	0	112.5	F255 W336 Q341 Y342 V343	F255-V339 HydrophobicContact CE1-CG1 4.19Å; F255-V339 HydrophobicContact CZ-CG1 4.09Å; W336-V339 HydrophobicContact CE3-CG2 4.38Å; W336-V339 WeakPolarHBondContact O-CB 3.43Å; W336-V339 VanDerWaalsContact O-CG2 3.26Å; W336-V339 WeakPolarHBondContact O-CG2 3.4Å; W336-V339 PolarHBondContact O-N 3.06Å; V339-Q341 PolarHBondContact O-N 3.1Å; V339-Y342 PolarHBondContact O-N 2.9Å; V339-V343 HydrophobicContact CG1-CG2 3.89Å; V339-V343 VanDerWaalsContact O-CG2 3.3Å; V339-V343 WeakPolarHBondContact O-CG2 3.13Å; V339-V343 PolarHBondContact O-N 3.26Å
340	P	92.1	Very high	91.1	Very high	66 Å²	66	35.8 Å²	35.8	43%	0.429	18%	0.176	S	C	.	.	H	α-helix	trans	-57.4	-46	179.5	-26.6	36.4	0	0	0	114.4	W337 Q338 V343 L344	W337-P340 WeakPolarHBondContact O-CD 3.34Å; Q338-P340 VanDerWaalsContact C-CD 3.45Å; Q338-P340 VanDerWaalsContact C-N 3.33Å; P340-V343 PolarHBondContact O-N 2.9Å; P340-L344 WeakPolarHBondContact O-CB 3.42Å; P340-L344 WeakPolarHBondContact O-CD1 3.25Å; P340-L344 WeakPolarHBondContact O-CG 3.36Å; P340-L344 PolarHBondContact O-N 3.41Å
341	Q	93.3	Very high	91.3	Very high	2 Å²	2	37.3 Å²	37.3	1%	0.009	18%	0.182	C	C	.	.	H	α-helix	trans	-65.7	-40.5	-179.4	61.9	-171.6	53.7	0	0	111.8	Y221 Q224 S298 A301 A302 Q338 V339 L344 I345	Y221-Q341 HydrophobicContact CD2-CG 4.24Å; Y221-Q341 HydrophobicContact CE2-CB 4.01Å; Y221-Q341 HydrophobicContact CE2-CG 4.04Å; Q224-Q341 VanDerWaalsContact OE1-NE2 3.14Å; S298-Q341 PolarHBondContact OG-O 3.03Å; A301-Q341 HydrophobicContact CB-CB 4.29Å; A302-Q341 HydrophobicContact CB-CB 4.5Å; A302-Q341 VanDerWaalsContact CB-OE1 3.29Å; Q338-Q341 HydrophobicContact CB-CG 4.34Å; Q338-Q341 WeakPolarHBondContact O-CG 3.44Å; Q338-Q341 PolarHBondContact O-N 3.27Å; V339-Q341 PolarHBondContact O-N 3.1Å; Q341-L344 PolarHBondContact O-N 3.48Å; Q341-I345 PolarHBondContact O-N 2.97Å
342	Y	90.1	Very high	91.4	Very high	4 Å²	4	37.3 Å²	37.3	2%	0.016	18%	0.182	C	C	.	.	H	α-helix	trans	-69.3	-40.2	177	-81.2	-89.7	0	0	0	112.7	M217 Y221 Q338 V339 L344 I345 G346	M217-Y342 HydrophobicContact CG-CD1 3.94Å; M217-Y342 HydrophobicContact CG-CE1 3.41Å; M217-Y342 VanDerWaalsContact CG-CE1 3.41Å; M217-Y342 HydrophobicContact SD-CD1 4.03Å; M217-Y342 HydrophobicContact SD-CE1 4Å; Y221-Y342 HydrophobicContact CD2-CE2 4.41Å; Q338-Y342 HydrophobicContact CB-CD2 4.22Å; Q338-Y342 HydrophobicContact CB-CE2 4.29Å; Q338-Y342 WeakPolarHBondContact O-CD2 3.09Å; Q338-Y342 PolarHBondContact O-N 3Å; V339-Y342 PolarHBondContact O-N 2.9Å; Y342-L344 VanDerWaalsContact C-N 3.31Å; Y342-L344 PolarHBondContact O-N 3.24Å; Y342-I345 PolarHBondContact O-N 3.35Å; Y342-G346 PolarHBondContact O-N 3.47Å
343	V	91.6	Very high	91.4	Very high	43 Å²	43	34.6 Å²	34.6	26%	0.261	17%	0.169	S	C	.	.	H	α-helix	trans	-60.2	-43.6	174.3	171.7	0	0	0	0	110.9	F255 L259 V339 P340 G346 I347	F255-V343 HydrophobicContact CE1-CG2 3.94Å; F255-V343 HydrophobicContact CZ-CG2 4.23Å; L259-V343 HydrophobicContact CD1-CB 4.39Å; L259-V343 HydrophobicContact CD1-CG2 3.92Å; L259-V343 HydrophobicContact CD2-CG2 4.3Å; V339-V343 HydrophobicContact CG1-CG2 3.89Å; V339-V343 VanDerWaalsContact O-CG2 3.3Å; V339-V343 WeakPolarHBondContact O-CG2 3.13Å; V339-V343 PolarHBondContact O-N 3.26Å; P340-V343 PolarHBondContact O-N 2.9Å; V343-G346 PolarHBondContact O-N 3.16Å; V343-I347 HydrophobicContact CG1-CD1 3.9Å; V343-I347 HydrophobicContact CG1-CG1 4.49Å; V343-I347 VanDerWaalsContact O-CG1 3.32Å; V343-I347 WeakPolarHBondContact O-CG1 3.47Å; V343-I347 PolarHBondContact O-N 2.74Å
344	L	94.9	Very high	91.3	Very high	37 Å²	37	36 Å²	36	19%	0.194	18%	0.176	C	C	.	.	H	α-helix	trans	-65.2	-38.3	178.3	-69.2	167.2	0	0	0	111.9	F294 C297 A301 P340 Q341 Y342 S348	F294-L344 HydrophobicContact CD1-CD2 3.68Å; F294-L344 HydrophobicContact CE1-CD2 4.23Å; C297-L344 HydrophobicContact CB-CD1 4.05Å; C297-L344 HydrophobicContact CB-CD2 4.29Å; A301-L344 HydrophobicContact CB-CD1 4.25Å; P340-L344 WeakPolarHBondContact O-CB 3.42Å; P340-L344 WeakPolarHBondContact O-CD1 3.25Å; P340-L344 WeakPolarHBondContact O-CG 3.36Å; P340-L344 PolarHBondContact O-N 3.41Å; Q341-L344 PolarHBondContact O-N 3.48Å; Y342-L344 VanDerWaalsContact C-N 3.31Å; Y342-L344 PolarHBondContact O-N 3.24Å; L344-S348 WeakPolarHBondContact O-CB 3.43Å; L344-S348 PolarHBondContact O-N 3.23Å
345	I	92.8	Very high	91.2	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-62.9	-47.6	171.7	-79.2	-177.2	0	0	0	111.8	Y214 M217 Y221 V295 S298 Q341 Y342 I347 S348 E349	Y214-I345 HydrophobicContact CD2-CG2 3.97Å; Y214-I345 HydrophobicContact CE2-CG2 3.92Å; M217-I345 HydrophobicContact CB-CD1 3.9Å; M217-I345 HydrophobicContact CE-CG2 4.18Å; M217-I345 HydrophobicContact SD-CG2 3.77Å; Y221-I345 HydrophobicContact CD2-CD1 4.01Å; Y221-I345 HydrophobicContact CE2-CD1 3.35Å; Y221-I345 HydrophobicContact CE2-CG1 4.42Å; V295-I345 HydrophobicContact CG2-CG1 4.49Å; S298-I345 WeakPolarHBondContact OG-CG1 3.23Å; Q341-I345 PolarHBondContact O-N 2.97Å; Y342-I345 PolarHBondContact O-N 3.35Å; I345-I347 PolarHBondContact O-N 3.27Å; I345-S348 CarbonylContact O-C 3.58Å; I345-S348 WeakPolarHBondContact O-CA 3.48Å; I345-S348 VanDerWaalsContact O-CB 3.23Å; I345-S348 WeakPolarHBondContact O-CB 3.34Å; I345-S348 PolarHBondContact O-N 3.32Å; I345-E349 PolarHBondContact O-N 3.02Å
346	G	90.8	Very high	91.3	Very high	0 Å²	0	33.3 Å²	33.3	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-61.9	-42.4	-179.7	0	0	0	0	0	112.6	D256 Y342 V343 S348 E349 I350	D256-G346 WeakPolarHBondContact OD1-CA 3.17Å; Y342-G346 PolarHBondContact O-N 3.47Å; V343-G346 PolarHBondContact O-N 3.16Å; G346-S348 VanDerWaalsContact C-N 3.3Å; G346-S348 PolarHBondContact O-N 2.99Å; G346-E349 PolarHBondContact O-N 2.03Å; G346-I350 WeakPolarHBondContact O-CG1 3.42Å; G346-I350 PolarHBondContact O-N 3.42Å
347	I	92.7	Very high	91.2	Very high	39 Å²	39	28.1 Å²	28.1	20%	0.2	14%	0.143	C	C	.	.	H	α-helix	trans	-60.7	-44.5	171.8	-66.3	168.3	0	0	0	110	L263 F294 V343 I345 E349 I350 F351	L263-I347 HydrophobicContact CD1-CG1 3.85Å; F294-I347 HydrophobicContact CB-CG2 4.44Å; F294-I347 HydrophobicContact CD1-CG2 4.13Å; F294-I347 HydrophobicContact CD2-CG2 3.55Å; F294-I347 HydrophobicContact CE1-CG2 4.25Å; F294-I347 HydrophobicContact CE2-CG2 3.68Å; F294-I347 HydrophobicContact CG-CB 4.47Å; F294-I347 HydrophobicContact CG-CG2 3.79Å; F294-I347 HydrophobicContact CZ-CG2 4.04Å; V343-I347 HydrophobicContact CG1-CD1 3.9Å; V343-I347 HydrophobicContact CG1-CG1 4.49Å; V343-I347 VanDerWaalsContact O-CG1 3.32Å; V343-I347 WeakPolarHBondContact O-CG1 3.47Å; V343-I347 PolarHBondContact O-N 2.74Å; I345-I347 PolarHBondContact O-N 3.27Å; I347-E349 PolarHBondContact O-N 3.35Å; I347-I350 PolarHBondContact O-N 3.35Å; I347-F351 HydrophobicContact CG2-CD2 3.93Å; I347-F351 HydrophobicContact CG2-CE2 4.11Å; I347-F351 VanDerWaalsContact O-CD2 3.31Å; I347-F351 WeakPolarHBondContact O-CD2 3.46Å; I347-F351 PolarHBondContact O-N 2.96Å
348	S	95.1	Very high	91	Very high	0 Å²	0	24.7 Å²	24.7	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-60.8	-42.5	-179.2	-177.6	0	0	0	0	113.1	Y210 G291 V295 L344 I345 G346 I350 F351 A352	Y210-S348 WeakPolarHBondContact CE2-OG 3.42Å; G291-S348 WeakPolarHBondContact O-CB 3.3Å; G291-S348 PolarHBondContact O-OG 3.01Å; V295-S348 WeakPolarHBondContact CB-OG 3.24Å; V295-S348 PolarHBondContact N-OG 3.36Å; L344-S348 WeakPolarHBondContact O-CB 3.43Å; L344-S348 PolarHBondContact O-N 3.23Å; I345-S348 CarbonylContact O-C 3.58Å; I345-S348 WeakPolarHBondContact O-CA 3.48Å; I345-S348 VanDerWaalsContact O-CB 3.23Å; I345-S348 WeakPolarHBondContact O-CB 3.34Å; I345-S348 PolarHBondContact O-N 3.32Å; G346-S348 VanDerWaalsContact C-N 3.3Å; G346-S348 PolarHBondContact O-N 2.99Å; S348-I350 VanDerWaalsContact C-N 3.31Å; S348-I350 PolarHBondContact O-N 3.45Å; S348-F351 PolarHBondContact O-N 3.43Å; S348-A352 WeakPolarHBondContact O-CB 3.4Å; S348-A352 PolarHBondContact O-N 3.37Å
349	E	92.4	Very high	90.8	Very high	31 Å²	31	25.6 Å²	25.6	15%	0.145	14%	0.137	C	C	.	.	H	α-helix	trans	-56.8	-44.6	178.2	-172.7	171.2	158.3	0	0	112.2	Y210 Y214 I260 I345 G346 I347 F351 S353 I354	Y210-E349 WeakPolarHBondContact OH-CA 3.3Å; Y214-E349 HydrophobicContact CE2-CB 4.11Å; Y214-E349 HydrophobicContact CE2-CG 4.15Å; Y214-E349 WeakPolarHBondContact CE2-OE2 3Å; Y214-E349 VanDerWaalsContact CZ-OE2 3.25Å; Y214-E349 VanDerWaalsContact OH-CD 3.29Å; Y214-E349 PolarHBondContact OH-OE2 2.97Å; I260-E349 VanDerWaalsContact CD1-CD 3.45Å; I260-E349 HydrophobicContact CD1-CG 4.43Å; I260-E349 VanDerWaalsContact CD1-OE2 3.3Å; I260-E349 WeakPolarHBondContact CD1-OE2 3.33Å; I345-E349 PolarHBondContact O-N 3.02Å; G346-E349 PolarHBondContact O-N 2.03Å; I347-E349 PolarHBondContact O-N 3.35Å; E349-F351 VanDerWaalsContact C-N 3.29Å; E349-F351 PolarHBondContact O-N 2.81Å; E349-S353 WeakPolarHBondContact O-CA 3.46Å; E349-S353 VanDerWaalsContact O-CB 3.31Å; E349-S353 WeakPolarHBondContact O-CB 3.03Å; E349-S353 PolarHBondContact O-N 2.86Å; E349-I354 PolarHBondContact O-N 3.33Å; E349-I354 VanDerWaalsContact O-N 3.08Å
350	I	90.4	Very high	90.6	Very high	3 Å²	3	23 Å²	23	2%	0.015	12%	0.122	C	C	.	.	H	α-helix	trans	-63.4	-37	-179.5	-67.8	170.6	0	0	0	112	L263 I264 K267 G346 I347 S348 I354	L263-I350 HydrophobicContact CB-CD1 3.25Å; L263-I350 HydrophobicContact CD1-CD1 4.06Å; L263-I350 HydrophobicContact CG-CD1 4.31Å; I264-I350 HydrophobicContact CG1-CD1 4.27Å; I264-I350 HydrophobicContact CG1-CG1 4.29Å; K267-I350 HydrophobicContact CB-CG2 4.48Å; K267-I350 HydrophobicContact CD-CG2 3.58Å; K267-I350 HydrophobicContact CG-CG2 4.31Å; G346-I350 WeakPolarHBondContact O-CG1 3.42Å; G346-I350 PolarHBondContact O-N 3.42Å; I347-I350 PolarHBondContact O-N 3.35Å; S348-I350 VanDerWaalsContact C-N 3.31Å; S348-I350 PolarHBondContact O-N 3.45Å; I350-I354 HydrophobicContact CG1-CD1 4.33Å
351	F	91.9	Very high	90.1	Very high	32 Å²	32	25.1 Å²	25.1	14%	0.14	12%	0.122	C	C	.	.	H	α-helix	trans	-90.9	-28.5	-176.1	-77.8	-71.3	0	0	0	113.9	R287 I288 V290 I347 S348 E349 A355	R287-F351 CarbonylContact C-O 3.56Å; R287-F351 HydrophobicContact CB-CD1 4.41Å; R287-F351 CarbonylContact O-C 3.29Å; I288-F351 WeakPolarHBondContact CA-O 3.36Å; I288-F351 PolarHBondContact N-O 2.83Å; V290-F351 HydrophobicContact CB-CB 4.5Å; V290-F351 HydrophobicContact CG1-CB 4.35Å; V290-F351 HydrophobicContact CG1-CD1 4.31Å; V290-F351 HydrophobicContact CG1-CD2 4.3Å; V290-F351 HydrophobicContact CG1-CG 4.07Å; I347-F351 HydrophobicContact CG2-CD2 3.93Å; I347-F351 HydrophobicContact CG2-CE2 4.11Å; I347-F351 VanDerWaalsContact O-CD2 3.31Å; I347-F351 WeakPolarHBondContact O-CD2 3.46Å; I347-F351 PolarHBondContact O-N 2.96Å; S348-F351 PolarHBondContact O-N 3.43Å; E349-F351 VanDerWaalsContact C-N 3.29Å; E349-F351 PolarHBondContact O-N 2.81Å; F351-A355 WeakPolarHBondContact O-CB 3.3Å
352	A	92.9	Very high	89.7	Confident	0 Å²	0	29.3 Å²	29.3	0%	0	15%	0.151	C	C	.	.	T	Hydrogen-bonded Turn	trans	-104.8	-58.5	-179.9	0	0	0	0	0	113.4	Y210 S348 G356	Y210-A352 HydrophobicContact CD1-CB 4.46Å; Y210-A352 HydrophobicContact CD2-CB 3.82Å; Y210-A352 HydrophobicContact CE1-CB 4.06Å; Y210-A352 HydrophobicContact CE2-CB 3.4Å; Y210-A352 HydrophobicContact CG-CB 4.34Å; S348-A352 WeakPolarHBondContact O-CB 3.4Å; S348-A352 PolarHBondContact O-N 3.37Å; A352-G356 WeakPolarHBondContact O-CA 3.46Å; A352-G356 PolarHBondContact O-N 3.44Å
353	S	90.8	Very high	89.2	Confident	18 Å²	18	31 Å²	31	13%	0.126	17%	0.166	C	C	.	.	H	α-helix	trans	-63	-57.2	-177.4	173.6	0	0	0	0	111.5	W211 E349 A355 G356 L357	W211-S353 WeakPolarHBondContact CH2-OG 3.39Å; E349-S353 WeakPolarHBondContact O-CA 3.46Å; E349-S353 VanDerWaalsContact O-CB 3.31Å; E349-S353 WeakPolarHBondContact O-CB 3.03Å; E349-S353 PolarHBondContact O-N 2.86Å; S353-A355 PolarHBondContact O-N 2.87Å; S353-G356 PolarHBondContact O-N 2.77Å; S353-L357 WeakPolarHBondContact O-CB 3.4Å; S353-L357 PolarHBondContact O-N 3.27Å
354	I	87.6	Confident	88.8	Confident	48 Å²	48	29.5 Å²	29.5	25%	0.246	16%	0.158	C	C	.	.	H	α-helix	trans	-64.3	-45.7	-178	-57.8	-177.6	0	0	0	110.8	I264 E349 I350 G356 L357 E358	I264-I354 HydrophobicContact CD1-CD1 4.1Å; I264-I354 HydrophobicContact CG1-CD1 4.43Å; E349-I354 PolarHBondContact O-N 3.33Å; E349-I354 VanDerWaalsContact O-N 3.08Å; I350-I354 HydrophobicContact CG1-CD1 4.33Å; I354-G356 VanDerWaalsContact C-N 3.34Å; I354-G356 PolarHBondContact O-N 2.83Å; I354-L357 PolarHBondContact O-N 3.45Å; I354-E358 WeakPolarHBondContact O-CG 3.21Å; I354-E358 PolarHBondContact O-N 3.34Å
355	A	88.8	Confident	88.1	Confident	0 Å²	0	29 Å²	29	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-67.1	-34.8	179.4	0	0	0	0	0	112.8	R287 I288 F351 S353 L357 F359	R287-A355 HydrophobicContact CB-CB 3.92Å; I288-A355 HydrophobicContact CG1-CB 4.06Å; F351-A355 WeakPolarHBondContact O-CB 3.3Å; S353-A355 PolarHBondContact O-N 2.87Å; A355-L357 VanDerWaalsContact C-N 3.33Å; A355-F359 VanDerWaalsContact O-CB 3.27Å; A355-F359 WeakPolarHBondContact O-CB 3.46Å; A355-F359 PolarHBondContact O-N 3.25Å
356	G	89.4	Confident	87.3	Confident	1 Å²	1	37.8 Å²	37.8	1%	0.01	20%	0.196	C	C	.	.	H	α-helix	trans	-63.2	-41.4	173.9	0	0	0	0	0	111.6	A352 S353 I354 F359 A360	A352-G356 WeakPolarHBondContact O-CA 3.46Å; A352-G356 PolarHBondContact O-N 3.44Å; S353-G356 PolarHBondContact O-N 2.77Å; I354-G356 VanDerWaalsContact C-N 3.34Å; I354-G356 PolarHBondContact O-N 2.83Å; G356-F359 PolarHBondContact O-N 3.12Å; G356-A360 WeakPolarHBondContact O-CB 3.28Å; G356-A360 PolarHBondContact O-N 3.46Å
357	L	86.8	Confident	86.7	Confident	49 Å²	49	41 Å²	41	26%	0.257	22%	0.218	S	C	.	.	H	α-helix	trans	-68.1	-44.8	175.8	-163	65.4	0	0	0	112.5	S353 I354 A355 F359 A360 Y361 M373 F376	S353-L357 WeakPolarHBondContact O-CB 3.4Å; S353-L357 PolarHBondContact O-N 3.27Å; I354-L357 PolarHBondContact O-N 3.45Å; A355-L357 VanDerWaalsContact C-N 3.33Å; L357-F359 VanDerWaalsContact C-N 3.31Å; L357-F359 PolarHBondContact O-N 3.34Å; L357-A360 PolarHBondContact O-N 3.38Å; L357-Y361 WeakPolarHBondContact O-CB 3.41Å; L357-Y361 PolarHBondContact O-N 3.19Å; L357-M373 HydrophobicContact CD1-CE 3.6Å; L357-M373 HydrophobicContact CD1-SD 3.24Å; L357-M373 WeakPolarHBondContact CD1-SD 3.43Å; L357-M373 HydrophobicContact CD2-CE 4.05Å; L357-M373 HydrophobicContact CD2-SD 4.04Å; L357-M373 HydrophobicContact CG-CE 3.89Å; L357-M373 HydrophobicContact CG-SD 4.04Å; L357-F376 HydrophobicContact CB-CE1 4.24Å; L357-F376 HydrophobicContact CB-CZ 4.08Å; L357-F376 HydrophobicContact CD1-CB 4.21Å; L357-F376 HydrophobicContact CD1-CD1 3.44Å; L357-F376 VanDerWaalsContact CD1-CD1 3.44Å; L357-F376 HydrophobicContact CD1-CD2 4.24Å; L357-F376 HydrophobicContact CD1-CE1 3.7Å; L357-F376 HydrophobicContact CD1-CE2 4.47Å; L357-F376 HydrophobicContact CD1-CG 3.71Å; L357-F376 HydrophobicContact CD1-CZ 4.19Å; L357-F376 HydrophobicContact CG-CE1 4.49Å
358	E	85.8	Confident	86	Confident	86 Å²	86	39.3 Å²	39.3	40%	0.402	21%	0.209	S	C	.	.	H	α-helix	trans	-58.5	-43	173.5	-75.2	173.1	-178.7	0	0	111.6	R287 I354 S362	R287-E358 IonicContact CZ-OE2 3.02Å; R287-E358 VanDerWaalsContact CZ-OE2 3.28Å; R287-E358 IonicContact NH1-OE2 3.62Å; R287-E358 PolarHBondContact NH1-OE2 3.38Å; R287-E358 IonicContact NH2-OE1 2.72Å; R287-E358 IonicContact NH2-OE2 2.97Å; R287-E358 PolarHBondContact NH2-OE2 2.99Å; I354-E358 WeakPolarHBondContact O-CG 3.21Å; I354-E358 PolarHBondContact O-N 3.34Å; E358-S362 VanDerWaalsContact O-CB 3.27Å; E358-S362 WeakPolarHBondContact O-CB 3.32Å; E358-S362 PolarHBondContact O-N 2.8Å; E358-S362 PolarHBondContact O-OG 3.44Å
359	F	86.4	Confident	85.1	Confident	22 Å²	22	41.4 Å²	41.4	10%	0.096	22%	0.219	C	C	.	.	H	α-helix	trans	-63.3	-49.1	175.9	173.2	-101.3	0	0	0	111.5	I200 V203 L285 I288 A355 G356 L357 Y361 S362 A363	I200-F359 HydrophobicContact CG2-CE1 4.09Å; V203-F359 HydrophobicContact CB-CE1 4.14Å; V203-F359 HydrophobicContact CG1-CD1 4.2Å; V203-F359 HydrophobicContact CG1-CE1 4.04Å; V203-F359 HydrophobicContact CG2-CE1 3.85Å; V203-F359 HydrophobicContact CG2-CZ 4.3Å; L285-F359 HydrophobicContact CD2-CD2 4.46Å; L285-F359 HydrophobicContact CD2-CE1 4.32Å; L285-F359 HydrophobicContact CD2-CE2 4.18Å; L285-F359 HydrophobicContact CD2-CZ 4.1Å; L285-F359 HydrophobicContact CG-CE2 4.45Å; I288-F359 HydrophobicContact CD1-CB 4.47Å; A355-F359 VanDerWaalsContact O-CB 3.27Å; A355-F359 WeakPolarHBondContact O-CB 3.46Å; A355-F359 PolarHBondContact O-N 3.25Å; G356-F359 PolarHBondContact O-N 3.12Å; L357-F359 VanDerWaalsContact C-N 3.31Å; L357-F359 PolarHBondContact O-N 3.34Å; F359-Y361 VanDerWaalsContact C-N 3.33Å; F359-Y361 PolarHBondContact O-N 3.09Å; F359-S362 PolarHBondContact O-N 3.31Å; F359-S362 PolarHBondContact O-OG 2.96Å; F359-S362 VanDerWaalsContact O-OG 3.13Å; F359-A363 WeakPolarHBondContact O-CB 3.35Å; F359-A363 PolarHBondContact O-N 3.09Å
360	A	85.9	Confident	84.4	Confident	1 Å²	1	44.1 Å²	44.1	1%	0.008	24%	0.241	C	C	.	.	H	α-helix	trans	-56.5	-47.3	177.8	0	0	0	0	0	111.8	F204 G356 L357 A364 I372	F204-A360 HydrophobicContact CE1-CB 3.79Å; F204-A360 HydrophobicContact CZ-CB 3.68Å; G356-A360 WeakPolarHBondContact O-CB 3.28Å; G356-A360 PolarHBondContact O-N 3.46Å; L357-A360 PolarHBondContact O-N 3.38Å; A360-A364 VanDerWaalsContact O-CB 3.31Å; A360-A364 WeakPolarHBondContact O-CB 3.45Å; A360-A364 PolarHBondContact O-N 3.23Å; A360-A364 VanDerWaalsContact O-N 3.13Å; A360-I372 HydrophobicContact CB-CG1 3.96Å
361	Y	82.6	Confident	84	Confident	112 Å²	112	44.2 Å²	44.2	44%	0.439	24%	0.242	S	C	.	.	H	α-helix	trans	-69.2	-38.9	-177.6	-167.9	-93.5	0	0	0	113	L357 F359 Q369 M373	L357-Y361 WeakPolarHBondContact O-CB 3.41Å; L357-Y361 PolarHBondContact O-N 3.19Å; F359-Y361 VanDerWaalsContact C-N 3.33Å; F359-Y361 PolarHBondContact O-N 3.09Å; Y361-Q369 HydrophobicContact CD2-CB 4.17Å; Y361-Q369 HydrophobicContact CD2-CG 4.2Å; Y361-Q369 HydrophobicContact CE2-CB 3.71Å; Y361-Q369 HydrophobicContact CE2-CG 3.87Å; Y361-Q369 VanDerWaalsContact CZ-NE2 3.29Å; Y361-Q369 VanDerWaalsContact CZ-OE1 3.3Å; Y361-Q369 PolarHBondContact OH-OE1 2.94Å; Y361-M373 HydrophobicContact CD2-CE 4.27Å
362	S	83.1	Confident	83.6	Confident	89 Å²	89	42.7 Å²	42.7	62%	0.622	24%	0.236	S	C	*	.	H	α-helix	trans	-76.6	-27	179.5	57.5	0	0	0	0	113.5	E358 F359	E358-S362 VanDerWaalsContact O-CB 3.27Å; E358-S362 WeakPolarHBondContact O-CB 3.32Å; E358-S362 PolarHBondContact O-N 2.8Å; E358-S362 PolarHBondContact O-OG 3.44Å; F359-S362 PolarHBondContact O-N 3.31Å; F359-S362 PolarHBondContact O-OG 2.96Å; F359-S362 VanDerWaalsContact O-OG 3.13Å
363	A	81.1	Confident	83.1	Confident	40 Å²	40	45.1 Å²	45.1	33%	0.331	25%	0.248	S	C	.	.	H	α-helix	trans	-85.2	-17.4	176.4	0	0	0	0	0	113.1	I200 F359	I200-A363 HydrophobicContact CD1-CB 3.44Å; I200-A363 VanDerWaalsContact CD1-CB 3.44Å; I200-A363 HydrophobicContact CG1-CB 3.88Å; F359-A363 WeakPolarHBondContact O-CB 3.35Å; F359-A363 PolarHBondContact O-N 3.09Å
364	A	81.7	Confident	82.8	Confident	11 Å²	11	45.8 Å²	45.8	9%	0.091	26%	0.258	C	S	.	.	S	Bend	trans	-83.9	145.9	180	0	0	0	0	0	113.1	A360 I372	A360-A364 VanDerWaalsContact O-CB 3.31Å; A360-A364 WeakPolarHBondContact O-CB 3.45Å; A360-A364 PolarHBondContact O-N 3.23Å; A360-A364 VanDerWaalsContact O-N 3.13Å; A364-I372 HydrophobicContact CB-CB 3.86Å; A364-I372 HydrophobicContact CB-CG1 4.17Å; A364-I372 HydrophobicContact CB-CG2 3.52Å
365	P	80.9	Confident	82.8	Confident	26 Å²	26	44.5 Å²	44.5	17%	0.169	25%	0.251	C	S	.	.			trans	-60.9	148.8	168.9	-16.4	27.5	0	0	0	111.9	E193 S367 M368 Q369	E193-P365 HydrophobicContact CB-CB 4.25Å; E193-P365 HydrophobicContact CB-CG 3.73Å; E193-P365 HydrophobicContact CG-CB 3.72Å; E193-P365 HydrophobicContact CG-CG 3.71Å; P365-S367 PolarHBondContact O-N 3.1Å; P365-M368 PolarHBondContact O-N 3.4Å; P365-Q369 WeakPolarHBondContact O-CG 3.31Å; P365-Q369 PolarHBondContact O-N 3.05Å
366	K	77	Confident	82.8	Confident	186 Å²	186	44.7 Å²	44.7	81%	0.809	25%	0.252	S	S	*	.	G	3₁₀ helix	trans	-55.9	-38.1	-178.4	-69	-174.8	179.8	177.2	0	113.1	M368	K366-M368 VanDerWaalsContact C-N 3.26Å; K366-M368 PolarHBondContact O-N 2.93Å
367	S	76.7	Confident	82.7	Confident	67 Å²	67	48.9 Å²	48.9	47%	0.469	27%	0.27	S	S	.	.	G	3₁₀ helix	trans	-67.5	-20.6	178	55.6	0	0	0	0	114	E193 P365	E193-S367 WeakPolarHBondContact OE1-CB 3.44Å; E193-S367 PolarHBondContact OE1-OG 3.19Å; E193-S367 PolarHBondContact OE2-OG 3.01Å; P365-S367 PolarHBondContact O-N 3.1Å
368	M	79	Confident	83	Confident	3 Å²	3	52.5 Å²	52.5	2%	0.015	28%	0.284	C	S	.	.	G	3₁₀ helix	trans	-118.3	15.3	-174	-60.2	-168.6	125.9	0	0	113.6	A145 M149 E193 V194 I197 P365 K366 S370 A371 I372	A145-M368 HydrophobicContact CB-CE 3.84Å; A145-M368 HydrophobicContact CB-CG 4.06Å; A145-M368 VanDerWaalsContact O-CE 3.29Å; A145-M368 WeakPolarHBondContact O-CE 3.44Å; M149-M368 HydrophobicContact CB-CE 4.38Å; E193-M368 HydrophobicContact CB-CG 4.49Å; E193-M368 HydrophobicContact CB-SD 3.71Å; V194-M368 HydrophobicContact CG2-CE 4.09Å; I197-M368 HydrophobicContact CD1-CB 3.9Å; I197-M368 HydrophobicContact CD1-CE 4.31Å; I197-M368 HydrophobicContact CD1-CG 4.3Å; I197-M368 HydrophobicContact CD1-SD 3.39Å; I197-M368 WeakPolarHBondContact CD1-SD 3.26Å; I197-M368 HydrophobicContact CG1-SD 4.32Å; P365-M368 PolarHBondContact O-N 3.4Å; K366-M368 VanDerWaalsContact C-N 3.26Å; K366-M368 PolarHBondContact O-N 2.93Å; M368-S370 VanDerWaalsContact C-N 3.33Å; M368-S370 PolarHBondContact O-N 3.07Å; M368-A371 HydrophobicContact CB-CB 4.44Å; M368-A371 WeakPolarHBondContact O-CB 3.31Å; M368-A371 PolarHBondContact O-N 2.83Å; M368-A371 VanDerWaalsContact O-N 3.07Å; M368-I372 PolarHBondContact O-N 3.03Å
369	Q	76.6	Confident	83.3	Confident	45 Å²	45	49 Å²	49	21%	0.21	27%	0.268	C	S	.	.	H	α-helix	trans	-61.6	-37	-178.7	-76.1	-178	-33.5	0	0	113.4	Y361 P365 A371 I372 M373	Y361-Q369 HydrophobicContact CD2-CB 4.17Å; Y361-Q369 HydrophobicContact CD2-CG 4.2Å; Y361-Q369 HydrophobicContact CE2-CB 3.71Å; Y361-Q369 HydrophobicContact CE2-CG 3.87Å; Y361-Q369 VanDerWaalsContact CZ-NE2 3.29Å; Y361-Q369 VanDerWaalsContact CZ-OE1 3.3Å; Y361-Q369 PolarHBondContact OH-OE1 2.94Å; P365-Q369 WeakPolarHBondContact O-CG 3.31Å; P365-Q369 PolarHBondContact O-N 3.05Å; Q369-A371 VanDerWaalsContact C-N 3.34Å; Q369-I372 VanDerWaalsContact O-CG2 3.23Å; Q369-I372 WeakPolarHBondContact O-CG2 3.43Å; Q369-M373 WeakPolarHBondContact O-CB 3.23Å; Q369-M373 PolarHBondContact O-N 2.9Å
370	S	77.6	Confident	83.6	Confident	87 Å²	87	48.9 Å²	48.9	61%	0.608	27%	0.269	S	S	*	.	H	α-helix	trans	-69	-34.3	174.4	-53.5	0	0	0	0	112.1	M368 M373 G374	M368-S370 VanDerWaalsContact C-N 3.33Å; M368-S370 PolarHBondContact O-N 3.07Å; S370-M373 PolarHBondContact O-N 3.06Å; S370-G374 PolarHBondContact O-N 3.25Å
371	A	80.9	Confident	83.9	Confident	5 Å²	5	50.7 Å²	50.7	4%	0.041	29%	0.288	C	S	.	.	H	α-helix	trans	-69.1	-43.5	179.2	0	0	0	0	0	111.9	A145 F146 M368 Q369 M373 G374 L375	A145-A371 HydrophobicContact CB-CB 4.09Å; F146-A371 HydrophobicContact CD2-CB 4Å; F146-A371 HydrophobicContact CE2-CB 3.63Å; F146-A371 HydrophobicContact CZ-CB 3.91Å; F146-A371 WeakPolarHBondContact CZ-O 3.38Å; M368-A371 HydrophobicContact CB-CB 4.44Å; M368-A371 WeakPolarHBondContact O-CB 3.31Å; M368-A371 PolarHBondContact O-N 2.83Å; M368-A371 VanDerWaalsContact O-N 3.07Å; Q369-A371 VanDerWaalsContact C-N 3.34Å; A371-M373 VanDerWaalsContact C-N 3.29Å; A371-M373 PolarHBondContact O-N 3.13Å; A371-G374 PolarHBondContact O-N 3.43Å; A371-L375 WeakPolarHBondContact O-CG 3.12Å; A371-L375 PolarHBondContact O-N 3.5Å
372	I	84.3	Confident	84.6	Confident	1 Å²	1	47.7 Å²	47.7	1%	0.005	28%	0.279	C	S	.	.	H	α-helix	trans	-64.8	-35.9	176.7	-160.7	72.6	0	0	0	111.7	I197 I200 F204 A360 A364 M368 Q369 L375 F376	I197-I372 HydrophobicContact CG1-CD1 4.4Å; I197-I372 HydrophobicContact CG2-CD1 4.1Å; I200-I372 HydrophobicContact CB-CD1 4.48Å; I200-I372 HydrophobicContact CD1-CD1 4.17Å; I200-I372 HydrophobicContact CG2-CD1 4.2Å; F204-I372 HydrophobicContact CE2-CD1 3.53Å; F204-I372 HydrophobicContact CE2-CG1 4.08Å; F204-I372 HydrophobicContact CZ-CD1 3.6Å; F204-I372 HydrophobicContact CZ-CG1 3.76Å; A360-I372 HydrophobicContact CB-CG1 3.96Å; A364-I372 HydrophobicContact CB-CB 3.86Å; A364-I372 HydrophobicContact CB-CG1 4.17Å; A364-I372 HydrophobicContact CB-CG2 3.52Å; M368-I372 PolarHBondContact O-N 3.03Å; Q369-I372 VanDerWaalsContact O-CG2 3.23Å; Q369-I372 WeakPolarHBondContact O-CG2 3.43Å; I372-L375 HydrophobicContact CD1-CD1 4.43Å; I372-L375 PolarHBondContact O-N 2.92Å; I372-F376 PolarHBondContact O-N 3.12Å
373	M	81.9	Confident	85.1	Confident	51 Å²	51	43.5 Å²	43.5	25%	0.251	25%	0.249	S	C	.	.	H	α-helix	trans	-63.7	-45.2	175.3	-172.9	65.1	62.2	0	0	111.2	L357 Y361 Q369 S370 A371 L375 F376 F377	L357-M373 HydrophobicContact CD1-CE 3.6Å; L357-M373 HydrophobicContact CD1-SD 3.24Å; L357-M373 WeakPolarHBondContact CD1-SD 3.43Å; L357-M373 HydrophobicContact CD2-CE 4.05Å; L357-M373 HydrophobicContact CD2-SD 4.04Å; L357-M373 HydrophobicContact CG-CE 3.89Å; L357-M373 HydrophobicContact CG-SD 4.04Å; Y361-M373 HydrophobicContact CD2-CE 4.27Å; Q369-M373 WeakPolarHBondContact O-CB 3.23Å; Q369-M373 PolarHBondContact O-N 2.9Å; S370-M373 PolarHBondContact O-N 3.06Å; A371-M373 VanDerWaalsContact C-N 3.29Å; A371-M373 PolarHBondContact O-N 3.13Å; M373-L375 PolarHBondContact O-N 3.25Å; M373-F376 WeakPolarHBondContact O-CB 3.35Å; M373-F376 PolarHBondContact O-N 3.44Å; M373-F377 HydrophobicContact CG-CD2 4.17Å; M373-F377 HydrophobicContact CG-CE2 3.84Å; M373-F377 VanDerWaalsContact O-CD2 3.3Å; M373-F377 WeakPolarHBondContact O-CD2 3.47Å; M373-F377 PolarHBondContact O-N 2.91Å; M373-F377 VanDerWaalsContact O-N 3.15Å; M373-F377 HydrophobicContact SD-CD2 4.35Å; M373-F377 HydrophobicContact SD-CE2 3.68Å; M373-F377 HydrophobicContact SD-CZ 4.32Å
374	G	84.4	Confident	85.6	Confident	32 Å²	32	42.5 Å²	42.5	33%	0.33	24%	0.24	S	C	.	.	H	α-helix	trans	-59.9	-44.5	174.3	0	0	0	0	0	112.4	S370 A371 F376 F377 F378	S370-G374 PolarHBondContact O-N 3.25Å; A371-G374 PolarHBondContact O-N 3.43Å; G374-F376 PolarHBondContact O-N 3.25Å; G374-F377 PolarHBondContact O-N 3.27Å; G374-F378 WeakPolarHBondContact O-CB 3.3Å; G374-F378 PolarHBondContact O-N 2.88Å
375	L	87.9	Confident	86.2	Confident	21 Å²	21	49.6 Å²	49.6	11%	0.11	27%	0.269	C	S	.	.	H	α-helix	trans	-60.8	-43	175.1	-74.4	171.6	0	0	0	111.9	F146 I197 L201 F204 A371 I372 M373 F377 F378 F379	F146-L375 HydrophobicContact CE1-CD1 4.4Å; F146-L375 HydrophobicContact CE1-CD2 3.98Å; F146-L375 HydrophobicContact CE1-CG 3.91Å; F146-L375 HydrophobicContact CZ-CD2 4.46Å; F146-L375 HydrophobicContact CZ-CG 4.04Å; I197-L375 HydrophobicContact CG2-CD1 3.76Å; L201-L375 HydrophobicContact CD2-CD1 4.45Å; F204-L375 HydrophobicContact CD2-CB 4.31Å; F204-L375 HydrophobicContact CE2-CB 3.94Å; A371-L375 WeakPolarHBondContact O-CG 3.12Å; A371-L375 PolarHBondContact O-N 3.5Å; I372-L375 HydrophobicContact CD1-CD1 4.43Å; I372-L375 PolarHBondContact O-N 2.92Å; M373-L375 PolarHBondContact O-N 3.25Å; L375-F377 PolarHBondContact O-N 3.06Å; L375-F378 WeakPolarHBondContact O-CB 3.12Å; L375-F378 PolarHBondContact O-N 3.42Å; L375-F379 VanDerWaalsContact O-CD2 3.25Å; L375-F379 WeakPolarHBondContact O-CD2 3.42Å; L375-F379 PolarHBondContact O-N 2.94Å
376	F	89.1	Confident	86.8	Confident	4 Å²	4	51.2 Å²	51.2	2%	0.018	28%	0.278	C	S	.	.	H	α-helix	trans	-58.2	-47.9	178.1	-177	-94.3	0	0	0	112.2	F204 L207 W211 L357 I372 M373 G374 F379 S380	F204-F376 HydrophobicContact CD1-CD2 4.38Å; F204-F376 AromaticContact CE1-CD2 3.99Å; F204-F376 HydrophobicContact CE1-CD2 3.99Å; F204-F376 HydrophobicContact CZ-CB 4.44Å; F204-F376 HydrophobicContact CZ-CD2 4.48Å; L207-F376 HydrophobicContact CD1-CE2 4.18Å; W211-F376 HydrophobicContact CH2-CE1 4.29Å; W211-F376 HydrophobicContact CH2-CZ 4.43Å; W211-F376 AromaticContact CZ2-CE1 3.65Å; W211-F376 HydrophobicContact CZ2-CE1 3.65Å; W211-F376 HydrophobicContact CZ2-CE2 4.45Å; W211-F376 AromaticContact CZ2-CZ 3.58Å; W211-F376 HydrophobicContact CZ2-CZ 3.58Å; L357-F376 HydrophobicContact CB-CE1 4.24Å; L357-F376 HydrophobicContact CB-CZ 4.08Å; L357-F376 HydrophobicContact CD1-CB 4.21Å; L357-F376 HydrophobicContact CD1-CD1 3.44Å; L357-F376 VanDerWaalsContact CD1-CD1 3.44Å; L357-F376 HydrophobicContact CD1-CD2 4.24Å; L357-F376 HydrophobicContact CD1-CE1 3.7Å; L357-F376 HydrophobicContact CD1-CE2 4.47Å; L357-F376 HydrophobicContact CD1-CG 3.71Å; L357-F376 HydrophobicContact CD1-CZ 4.19Å; L357-F376 HydrophobicContact CG-CE1 4.49Å; I372-F376 PolarHBondContact O-N 3.12Å; M373-F376 WeakPolarHBondContact O-CB 3.35Å; M373-F376 PolarHBondContact O-N 3.44Å; G374-F376 PolarHBondContact O-N 3.25Å; F376-F379 PolarHBondContact O-N 3.18Å; F376-S380 PolarHBondContact O-N 3.28Å
377	F	88	Confident	87.4	Confident	89 Å²	89	42.4 Å²	42.4	39%	0.39	24%	0.24	S	C	.	.	H	α-helix	trans	-67.5	-35	176.1	-73.2	-58.9	0	0	0	113	M373 G374 L375 S380 G381	M373-F377 HydrophobicContact CG-CD2 4.17Å; M373-F377 HydrophobicContact CG-CE2 3.84Å; M373-F377 VanDerWaalsContact O-CD2 3.3Å; M373-F377 WeakPolarHBondContact O-CD2 3.47Å; M373-F377 PolarHBondContact O-N 2.91Å; M373-F377 VanDerWaalsContact O-N 3.15Å; M373-F377 HydrophobicContact SD-CD2 4.35Å; M373-F377 HydrophobicContact SD-CE2 3.68Å; M373-F377 HydrophobicContact SD-CZ 4.32Å; G374-F377 PolarHBondContact O-N 3.27Å; L375-F377 PolarHBondContact O-N 3.06Å; F377-S380 WeakPolarHBondContact O-CB 3.28Å; F377-S380 PolarHBondContact O-N 3.36Å; F377-G381 PolarHBondContact O-N 3.48Å
378	F	91.3	Very high	88	Confident	125 Å²	125	42 Å²	42	55%	0.548	24%	0.237	S	C	.	.	H	α-helix	trans	-60.2	-47.3	174.3	174.1	-104.6	0	0	0	111.7	G374 L375 S380 G381 I382	G374-F378 WeakPolarHBondContact O-CB 3.3Å; G374-F378 PolarHBondContact O-N 2.88Å; L375-F378 WeakPolarHBondContact O-CB 3.12Å; L375-F378 PolarHBondContact O-N 3.42Å; F378-S380 VanDerWaalsContact C-N 3.34Å; F378-S380 PolarHBondContact O-N 3.11Å; F378-G381 PolarHBondContact O-N 3.49Å; F378-I382 HydrophobicContact CD1-CD1 3.75Å; F378-I382 HydrophobicContact CE1-CD1 3.26Å; F378-I382 HydrophobicContact CE1-CG1 4.26Å; F378-I382 HydrophobicContact CE2-CD1 4.35Å; F378-I382 HydrophobicContact CG-CD1 4.49Å; F378-I382 HydrophobicContact CZ-CD1 3.6Å; F378-I382 HydrophobicContact CZ-CG1 4.25Å; F378-I382 WeakPolarHBondContact O-CG1 3.47Å; F378-I382 PolarHBondContact O-N 2.87Å
379	F	93.6	Very high	88.6	Confident	13 Å²	13	43.3 Å²	43.3	6%	0.057	25%	0.251	C	S	.	.	H	α-helix	trans	-67.1	-32.8	176.2	-82.9	-77.9	0	0	0	113.2	L201 F204 F205 I208 L375 F376 I382 G383	L201-F379 HydrophobicContact CD2-CE2 3.87Å; L201-F379 HydrophobicContact CD2-CZ 4.27Å; F204-F379 HydrophobicContact CB-CB 4.2Å; F204-F379 HydrophobicContact CB-CD1 4.22Å; F204-F379 HydrophobicContact CB-CD2 3.61Å; F204-F379 HydrophobicContact CB-CE2 4.01Å; F204-F379 HydrophobicContact CB-CG 3.74Å; F204-F379 HydrophobicContact CB-CZ 4.46Å; F204-F379 AromaticContact CD2-CD2 3.81Å; F204-F379 HydrophobicContact CD2-CD2 3.81Å; F204-F379 HydrophobicContact CD2-CE2 4.09Å; F204-F379 HydrophobicContact CG-CD2 4.13Å; F205-F379 AromaticContact CD1-CE1 3.71Å; F205-F379 HydrophobicContact CD1-CE1 3.71Å; F205-F379 HydrophobicContact CD1-CZ 4.46Å; F205-F379 HydrophobicContact CD2-CE1 4.1Å; F205-F379 HydrophobicContact CD2-CZ 4.16Å; F205-F379 AromaticContact CE1-CE1 3.56Å; F205-F379 HydrophobicContact CE1-CE1 3.56Å; F205-F379 HydrophobicContact CE1-CZ 4.07Å; F205-F379 AromaticContact CE2-CE1 3.94Å; F205-F379 HydrophobicContact CE2-CE1 3.94Å; F205-F379 AromaticContact CE2-CZ 3.72Å; F205-F379 HydrophobicContact CE2-CZ 3.72Å; F205-F379 AromaticContact CG-CE1 3.97Å; F205-F379 HydrophobicContact CG-CE1 3.97Å; F205-F379 HydrophobicContact CG-CZ 4.49Å; F205-F379 AromaticContact CZ-CE1 3.67Å; F205-F379 HydrophobicContact CZ-CE1 3.67Å; F205-F379 AromaticContact CZ-CZ 3.67Å; F205-F379 HydrophobicContact CZ-CZ 3.67Å; I208-F379 HydrophobicContact CD1-CD1 3.88Å; I208-F379 HydrophobicContact CD1-CE1 4.2Å; I208-F379 HydrophobicContact CG1-CD1 3.97Å; L375-F379 VanDerWaalsContact O-CD2 3.25Å; L375-F379 WeakPolarHBondContact O-CD2 3.42Å; L375-F379 PolarHBondContact O-N 2.94Å; F376-F379 PolarHBondContact O-N 3.18Å; F379-I382 HydrophobicContact CD1-CD1 4.11Å; F379-I382 HydrophobicContact CE1-CD1 4.33Å; F379-I382 PolarHBondContact O-N 3.16Å; F379-G383 PolarHBondContact O-N 3.16Å
380	S	92.1	Very high	89.3	Confident	19 Å²	19	42.7 Å²	42.7	13%	0.133	25%	0.249	C	C	.	.	H	α-helix	trans	-60.2	-47.4	169.4	178.1	0	0	0	0	111.5	W211 F376 F377 F378 I382 G383 S384	W211-S380 VanDerWaalsContact CD2-OG 3.28Å; W211-S380 VanDerWaalsContact CE3-OG 3.27Å; F376-S380 PolarHBondContact O-N 3.28Å; F377-S380 WeakPolarHBondContact O-CB 3.28Å; F377-S380 PolarHBondContact O-N 3.36Å; F378-S380 VanDerWaalsContact C-N 3.34Å; F378-S380 PolarHBondContact O-N 3.11Å; S380-I382 PolarHBondContact O-N 3.25Å; S380-G383 WeakPolarHBondContact O-CA 3.39Å; S380-G383 PolarHBondContact O-N 2.83Å; S380-G383 VanDerWaalsContact O-N 3.07Å; S380-S384 PolarHBondContact O-N 2.91Å; S380-S384 VanDerWaalsContact O-N 3.07Å; S380-S384 PolarHBondContact O-OG 3.45Å
381	G	93	Very high	89.8	Confident	38 Å²	38	40.2 Å²	40.2	39%	0.392	23%	0.229	S	C	.	.	H	α-helix	trans	-61.1	-39.7	174.8	0	0	0	0	0	113.4	F377 F378 G383 S384 F385	F377-G381 PolarHBondContact O-N 3.48Å; F378-G381 PolarHBondContact O-N 3.49Å; G381-G383 VanDerWaalsContact C-N 3.31Å; G381-G383 PolarHBondContact O-N 2.75Å; G381-S384 PolarHBondContact O-N 2.98Å; G381-F385 WeakPolarHBondContact O-CB 3.49Å; G381-F385 PolarHBondContact O-N 2.94Å
382	I	95.6	Very high	90	Very high	50 Å²	50	42.9 Å²	42.9	26%	0.256	25%	0.252	S	S	.	.	H	α-helix	trans	-58.7	-44.2	171.9	-69.7	167.6	0	0	0	110.3	I208 F378 F379 S380 S384 F385 V386	I208-I382 HydrophobicContact CD1-CG2 4.06Å; I208-I382 HydrophobicContact CG1-CG2 4.37Å; I208-I382 HydrophobicContact CG2-CG2 4.25Å; F378-I382 HydrophobicContact CD1-CD1 3.75Å; F378-I382 HydrophobicContact CE1-CD1 3.26Å; F378-I382 HydrophobicContact CE1-CG1 4.26Å; F378-I382 HydrophobicContact CE2-CD1 4.35Å; F378-I382 HydrophobicContact CG-CD1 4.49Å; F378-I382 HydrophobicContact CZ-CD1 3.6Å; F378-I382 HydrophobicContact CZ-CG1 4.25Å; F378-I382 WeakPolarHBondContact O-CG1 3.47Å; F378-I382 PolarHBondContact O-N 2.87Å; F379-I382 HydrophobicContact CD1-CD1 4.11Å; F379-I382 HydrophobicContact CE1-CD1 4.33Å; F379-I382 PolarHBondContact O-N 3.16Å; S380-I382 PolarHBondContact O-N 3.25Å; I382-S384 PolarHBondContact O-N 2.82Å; I382-F385 PolarHBondContact O-N 3.27Å; I382-V386 HydrophobicContact CG2-CG2 4.05Å; I382-V386 VanDerWaalsContact O-CG2 3.26Å; I382-V386 WeakPolarHBondContact O-CG2 3.33Å; I382-V386 PolarHBondContact O-N 2.98Å
383	G	94.8	Very high	90.3	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-57.4	-47.7	176.3	0	0	0	0	0	113	M212 F379 S380 G381 F385 V386 G387	M212-G383 WeakPolarHBondContact CA-O 3.3Å; F379-G383 PolarHBondContact O-N 3.16Å; S380-G383 WeakPolarHBondContact O-CA 3.39Å; S380-G383 PolarHBondContact O-N 2.83Å; S380-G383 VanDerWaalsContact O-N 3.07Å; G381-G383 VanDerWaalsContact C-N 3.31Å; G381-G383 PolarHBondContact O-N 2.75Å; G383-F385 VanDerWaalsContact C-N 3.34Å; G383-F385 PolarHBondContact O-N 3.43Å; G383-V386 PolarHBondContact O-N 3.41Å; G383-G387 PolarHBondContact O-N 2.56Å
384	S	91.6	Very high	90.6	Very high	20 Å²	20	45 Å²	45	14%	0.14	26%	0.263	C	S	.	.	H	α-helix	trans	-61.1	-41.3	175.1	-59.5	0	0	0	0	112.6	F215 S380 G381 I382 G387 S388	F215-S384 WeakPolarHBondContact CD2-OG 3.43Å; F215-S384 VanDerWaalsContact CG-OG 3.3Å; F215-S384 WeakPolarHBondContact CG-OG 3.41Å; S380-S384 PolarHBondContact O-N 2.91Å; S380-S384 VanDerWaalsContact O-N 3.07Å; S380-S384 PolarHBondContact O-OG 3.45Å; G381-S384 PolarHBondContact O-N 2.98Å; I382-S384 PolarHBondContact O-N 2.82Å; S384-G387 PolarHBondContact O-N 3.33Å; S384-S388 PolarHBondContact O-N 3.3Å; S384-S388 PolarHBondContact O-OG 3.35Å
385	F	93.3	Very high	90.6	Very high	160 Å²	160	45.3 Å²	45.3	70%	0.702	26%	0.26	S	S	*	.	H	α-helix	trans	-65.5	-46.7	178	-176.2	-98.9	0	0	0	111.8	G381 I382 G383 G387 S388 G389	G381-F385 WeakPolarHBondContact O-CB 3.49Å; G381-F385 PolarHBondContact O-N 2.94Å; I382-F385 PolarHBondContact O-N 3.27Å; G383-F385 VanDerWaalsContact C-N 3.34Å; G383-F385 PolarHBondContact O-N 3.43Å; F385-G387 VanDerWaalsContact C-N 3.3Å; F385-G387 PolarHBondContact O-N 3.33Å; F385-S388 PolarHBondContact O-N 3.4Å; F385-G389 PolarHBondContact O-N 3.01Å
386	V	94	Very high	90.4	Very high	60 Å²	60	48.9 Å²	48.9	36%	0.364	28%	0.279	S	S	.	.	H	α-helix	trans	-62.5	-39.2	176.1	177.5	0	0	0	0	110.6	M212 I382 G383 G389 L390	M212-V386 HydrophobicContact CE-CB 4.12Å; M212-V386 HydrophobicContact CE-CG1 3.39Å; M212-V386 HydrophobicContact SD-CG1 4.5Å; I382-V386 HydrophobicContact CG2-CG2 4.05Å; I382-V386 VanDerWaalsContact O-CG2 3.26Å; I382-V386 WeakPolarHBondContact O-CG2 3.33Å; I382-V386 PolarHBondContact O-N 2.98Å; G383-V386 PolarHBondContact O-N 3.41Å; V386-G389 PolarHBondContact O-N 3.4Å; V386-L390 WeakPolarHBondContact O-CB 3.21Å; V386-L390 PolarHBondContact O-N 2.92Å
387	G	90.9	Very high	89.8	Confident	0 Å²	0	56.6 Å²	56.6	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-62.9	-42.1	175.9	0	0	0	0	0	113.2	G383 S384 F385 L390 L391 Y419	G383-G387 PolarHBondContact O-N 2.56Å; S384-G387 PolarHBondContact O-N 3.33Å; F385-G387 VanDerWaalsContact C-N 3.3Å; F385-G387 PolarHBondContact O-N 3.33Å; G387-L390 PolarHBondContact O-N 3.46Å; G387-L391 WeakPolarHBondContact O-CB 3.44Å; G387-L391 PolarHBondContact O-N 3.02Å; G387-Y419 PolarHBondContact O-OH 3.35Å
388	S	89.1	Confident	89.4	Confident	58 Å²	58	57.5 Å²	57.5	41%	0.406	33%	0.33	S	S	.	.	H	α-helix	trans	-67	-40.5	175.2	-55.2	0	0	0	0	111.6	S384 F385 L391 A392	S384-S388 PolarHBondContact O-N 3.3Å; S384-S388 PolarHBondContact O-OG 3.35Å; F385-S388 PolarHBondContact O-N 3.4Å; S388-L391 WeakPolarHBondContact O-CB 3.12Å; S388-L391 PolarHBondContact O-N 3.47Å; S388-A392 PolarHBondContact O-N 2.93Å
389	G	90.3	Very high	88.9	Confident	31 Å²	31	54.8 Å²	54.8	32%	0.32	32%	0.32	S	S	.	.	H	α-helix	trans	-63.7	-42.3	174.2	0	0	0	0	0	112.6	F385 V386 L391 A392 I393	F385-G389 PolarHBondContact O-N 3.01Å; V386-G389 PolarHBondContact O-N 3.4Å; G389-L391 VanDerWaalsContact C-N 3.33Å; G389-L391 PolarHBondContact O-N 2.93Å; G389-A392 WeakPolarHBondContact O-CB 3.41Å; G389-A392 PolarHBondContact O-N 2.98Å; G389-I393 WeakPolarHBondContact O-CG1 3.49Å; G389-I393 PolarHBondContact O-N 3.41Å
390	L	91.5	Very high	88	Confident	32 Å²	32	55.2 Å²	55.2	17%	0.168	33%	0.329	C	S	.	.	H	α-helix	trans	-62.5	-42.2	174.6	-175.9	63.1	0	0	0	111.2	M212 V386 G387 A392 I393 V394 Y419 L422 L423 I426	M212-L390 HydrophobicContact SD-CD2 4Å; V386-L390 WeakPolarHBondContact O-CB 3.21Å; V386-L390 PolarHBondContact O-N 2.92Å; G387-L390 PolarHBondContact O-N 3.46Å; L390-A392 VanDerWaalsContact C-N 3.33Å; L390-A392 PolarHBondContact O-N 2.89Å; L390-I393 PolarHBondContact O-N 3.38Å; L390-V394 PolarHBondContact O-N 3.36Å; L390-Y419 HydrophobicContact CD2-CE2 4.22Å; L390-Y419 HydrophobicContact CG-CE2 4.14Å; L390-L422 HydrophobicContact CD1-CD2 4.16Å; L390-L422 HydrophobicContact CD2-CD2 4.14Å; L390-L422 HydrophobicContact CG-CD2 4.4Å; L390-L423 HydrophobicContact CD2-CD2 3.99Å; L390-I426 HydrophobicContact CD2-CD1 3.78Å
391	L	87.4	Confident	87.6	Confident	35 Å²	35	57.8 Å²	57.8	18%	0.183	34%	0.335	C	S	.	.	H	α-helix	trans	-59.7	-43.6	174.8	-172.1	65.9	0	0	0	111.6	T220 G387 S388 G389 I393 V394 S395 M402 Y419	T220-L391 HydrophobicContact CG2-CD1 3.87Å; T220-L391 HydrophobicContact CG2-CD2 3.9Å; G387-L391 WeakPolarHBondContact O-CB 3.44Å; G387-L391 PolarHBondContact O-N 3.02Å; S388-L391 WeakPolarHBondContact O-CB 3.12Å; S388-L391 PolarHBondContact O-N 3.47Å; G389-L391 VanDerWaalsContact C-N 3.33Å; G389-L391 PolarHBondContact O-N 2.93Å; L391-I393 VanDerWaalsContact C-N 3.35Å; L391-I393 PolarHBondContact O-N 2.92Å; L391-V394 HydrophobicContact CD1-CG2 4.31Å; L391-V394 VanDerWaalsContact O-CG2 3.23Å; L391-V394 WeakPolarHBondContact O-CG2 3.15Å; L391-V394 PolarHBondContact O-N 3.33Å; L391-S395 WeakPolarHBondContact O-CB 3.41Å; L391-S395 PolarHBondContact O-N 3.29Å; L391-S395 VanDerWaalsContact O-N 3.1Å; L391-M402 HydrophobicContact CD1-CB 4.35Å; L391-M402 HydrophobicContact CD1-CE 4.01Å; L391-M402 HydrophobicContact CD1-CG 3.74Å; L391-M402 HydrophobicContact CD1-SD 3.83Å; L391-M402 HydrophobicContact CD2-CE 4.31Å; L391-M402 HydrophobicContact CG-CG 4.3Å; L391-Y419 HydrophobicContact CB-CE2 4.29Å; L391-Y419 HydrophobicContact CD1-CD1 4.15Å; L391-Y419 HydrophobicContact CD1-CD2 4.33Å; L391-Y419 HydrophobicContact CD1-CE1 3.83Å; L391-Y419 HydrophobicContact CD1-CE2 4.01Å; L391-Y419 HydrophobicContact CD1-CG 4.38Å
392	A	86.9	Confident	86.8	Confident	62 Å²	62	57.6 Å²	57.6	51%	0.512	32%	0.324	S	S	.	.	H	α-helix	trans	-62.4	-40.1	176.4	0	0	0	0	0	112.2	S388 G389 L390 S395	S388-A392 PolarHBondContact O-N 2.93Å; G389-A392 WeakPolarHBondContact O-CB 3.41Å; G389-A392 PolarHBondContact O-N 2.98Å; L390-A392 VanDerWaalsContact C-N 3.33Å; L390-A392 PolarHBondContact O-N 2.89Å; A392-S395 WeakPolarHBondContact O-CB 3.39Å; A392-S395 PolarHBondContact O-N 3.18Å
393	I	88.9	Confident	85.4	Confident	91 Å²	91	56 Å²	56	47%	0.467	32%	0.318	S	S	.	.	H	α-helix	trans	-63.1	-48.8	176.5	-68.9	165.1	0	0	0	110.9	G389 L390 L391 S395 L396 I399	G389-I393 WeakPolarHBondContact O-CG1 3.49Å; G389-I393 PolarHBondContact O-N 3.41Å; L390-I393 PolarHBondContact O-N 3.38Å; L391-I393 VanDerWaalsContact C-N 3.35Å; L391-I393 PolarHBondContact O-N 2.92Å; I393-S395 PolarHBondContact O-N 3.47Å; I393-L396 VanDerWaalsContact O-CB 3.28Å; I393-L396 WeakPolarHBondContact O-CB 3.32Å; I393-L396 VanDerWaalsContact O-CG 3.23Å; I393-L396 WeakPolarHBondContact O-CG 3.18Å; I393-L396 PolarHBondContact O-N 3.11Å; I393-I399 HydrophobicContact CG2-CD1 4.18Å
394	V	88.6	Confident	83.9	Confident	5 Å²	5	56.8 Å²	56.8	3%	0.03	32%	0.324	C	S	.	.	H	α-helix	trans	-70.4	-13	-179.2	-57.2	0	0	0	0	113.1	L390 L391 I399 W401 M402 Y419 L422	L390-V394 PolarHBondContact O-N 3.36Å; L391-V394 HydrophobicContact CD1-CG2 4.31Å; L391-V394 VanDerWaalsContact O-CG2 3.23Å; L391-V394 WeakPolarHBondContact O-CG2 3.15Å; L391-V394 PolarHBondContact O-N 3.33Å; V394-I399 HydrophobicContact CB-CG2 4.3Å; V394-W401 HydrophobicContact CB-CB 4.17Å; V394-W401 HydrophobicContact CB-CD2 4.46Å; V394-W401 HydrophobicContact CB-CE3 4.08Å; V394-W401 HydrophobicContact CG1-CE3 3.89Å; V394-W401 HydrophobicContact CG1-CZ3 4.28Å; V394-W401 PolarHBondContact O-N 3.45Å; V394-M402 HydrophobicContact CG2-CB 4.35Å; V394-Y419 HydrophobicContact CG1-CD2 4.38Å; V394-Y419 HydrophobicContact CG2-CD2 3.74Å; V394-Y419 HydrophobicContact CG2-CE2 4.27Å; V394-Y419 HydrophobicContact CG2-CG 4.4Å; V394-L422 HydrophobicContact CG1-CD2 4.35Å
395	S	84.2	Confident	82.5	Confident	38 Å²	38	59.3 Å²	59.3	27%	0.266	33%	0.333	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85	-5.1	172.5	-168	0	0	0	0	113.8	L391 A392 I393 S403	L391-S395 WeakPolarHBondContact O-CB 3.41Å; L391-S395 PolarHBondContact O-N 3.29Å; L391-S395 VanDerWaalsContact O-N 3.1Å; A392-S395 WeakPolarHBondContact O-CB 3.39Å; A392-S395 PolarHBondContact O-N 3.18Å; I393-S395 PolarHBondContact O-N 3.47Å; S395-S403 VanDerWaalsContact OG-CB 3.31Å; S395-S403 WeakPolarHBondContact OG-CB 3.48Å
396	L	83.7	Confident	80.9	Confident	96 Å²	96	59.8 Å²	59.8	50%	0.503	34%	0.335	S	S	.	.	S	Bend	trans	-63.2	149	176.1	-69.2	173.1	0	0	0	111.3	I393 S398 I399 G400	I393-L396 VanDerWaalsContact O-CB 3.28Å; I393-L396 WeakPolarHBondContact O-CB 3.32Å; I393-L396 VanDerWaalsContact O-CG 3.23Å; I393-L396 WeakPolarHBondContact O-CG 3.18Å; I393-L396 PolarHBondContact O-N 3.11Å; L396-S398 PolarHBondContact O-N 3.22Å; L396-S398 VanDerWaalsContact O-N 3.12Å; L396-I399 PolarHBondContact O-N 3.49Å; L396-G400 PolarHBondContact O-N 3.07Å
397	K	76.9	Confident	79.4	Confident	166 Å²	166	58.5 Å²	58.5	72%	0.722	33%	0.326	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.1	-25.3	-176.4	-173.3	171.3	-178	-176.4	0	115.9	H405	K397-H405 WeakPolarHBondContact CA-NE2 3.49Å; K397-H405 WeakPolarHBondContact CB-NE2 3.43Å
398	S	79.1	Confident	78	Confident	109 Å²	109	62 Å²	62	76%	0.762	34%	0.341	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.9	-26.4	173.7	51	0	0	0	0	113.5	L396	L396-S398 PolarHBondContact O-N 3.22Å; L396-S398 VanDerWaalsContact O-N 3.12Å
399	I	81.8	Confident	76.7	Confident	68 Å²	68	60.9 Å²	60.9	35%	0.349	34%	0.339	S	S	.	.	T	Hydrogen-bonded Turn	trans	-104.1	-49.9	-175.7	-59.6	178.5	0	0	0	110.5	I393 V394 L396 W401	I393-I399 HydrophobicContact CG2-CD1 4.18Å; V394-I399 HydrophobicContact CB-CG2 4.3Å; L396-I399 PolarHBondContact O-N 3.49Å; I399-W401 VanDerWaalsContact C-N 3.31Å; I399-W401 HydrophobicContact CG2-CB 4.3Å; I399-W401 VanDerWaalsContact CG2-CD1 3.47Å; I399-W401 HydrophobicContact CG2-CD2 3.75Å; I399-W401 HydrophobicContact CG2-CG 3.59Å; I399-W401 PolarHBondContact O-N 3.01Å
400	G	75	Confident	76	Confident	22 Å²	22	60.2 Å²	60.2	23%	0.227	33%	0.328	C	S	.	.			trans	65.4	22.9	171.1	0	0	0	0	0	115.6	L396	L396-G400 PolarHBondContact O-N 3.07Å
401	W	83.7	Confident	75.6	Confident	73 Å²	73	58.8 Å²	58.8	28%	0.277	32%	0.32	S	S	.	.	S	Bend	trans	-76.9	-24.8	-176.5	-67.8	2.2	0	0	0	113.5	V394 I399 C414 S415 L416 Y418 L422	V394-W401 HydrophobicContact CB-CB 4.17Å; V394-W401 HydrophobicContact CB-CD2 4.46Å; V394-W401 HydrophobicContact CB-CE3 4.08Å; V394-W401 HydrophobicContact CG1-CE3 3.89Å; V394-W401 HydrophobicContact CG1-CZ3 4.28Å; V394-W401 PolarHBondContact O-N 3.45Å; I399-W401 VanDerWaalsContact C-N 3.31Å; I399-W401 HydrophobicContact CG2-CB 4.3Å; I399-W401 VanDerWaalsContact CG2-CD1 3.47Å; I399-W401 HydrophobicContact CG2-CD2 3.75Å; I399-W401 HydrophobicContact CG2-CG 3.59Å; I399-W401 PolarHBondContact O-N 3.01Å; W401-C414 WeakPolarHBondContact O-CB 3.44Å; W401-S415 CarbonylContact O-C 3.21Å; W401-S415 PolarHBondContact O-N 3.45Å; W401-S415 VanDerWaalsContact O-N 3.17Å; W401-L416 PolarHBondContact O-N 3.18Å; W401-Y418 HydrophobicContact CD2-CD2 4.36Å; W401-Y418 HydrophobicContact CD2-CG 4.46Å; W401-Y418 HydrophobicContact CG-CD2 4.49Å; W401-Y418 HydrophobicContact CZ2-CD2 4.46Å; W401-Y418 HydrophobicContact CZ2-CG 4.36Å; W401-Y418 AromaticContact NE1-CD2 3.93Å; W401-L422 HydrophobicContact CZ3-CB 4.22Å; W401-L422 HydrophobicContact CZ3-CD2 3.98Å
402	M	75	Confident	75.5	Confident	33 Å²	33	58.1 Å²	58.1	16%	0.163	32%	0.317	C	S	.	.	S	Bend	trans	-119.1	-21.2	-172.7	-173.4	61.8	178.9	0	0	114.2	T220 L223 L391 V394 C414 L416	T220-M402 HydrophobicContact CG2-CE 4.11Å; L223-M402 HydrophobicContact CD2-CE 3.2Å; L223-M402 HydrophobicContact CD2-SD 4.38Å; L391-M402 HydrophobicContact CD1-CB 4.35Å; L391-M402 HydrophobicContact CD1-CE 4.01Å; L391-M402 HydrophobicContact CD1-CG 3.74Å; L391-M402 HydrophobicContact CD1-SD 3.83Å; L391-M402 HydrophobicContact CD2-CE 4.31Å; L391-M402 HydrophobicContact CG-CG 4.3Å; V394-M402 HydrophobicContact CG2-CB 4.35Å; M402-C414 VanDerWaalsContact C-SG 3.59Å; M402-L416 HydrophobicContact SD-CD1 3.62Å
403	S	66.7	Low	75.1	Confident	17 Å²	17	57.6 Å²	57.6	12%	0.119	32%	0.318	C	S	.	.			trans	-131.6	126.2	177.9	-178.8	0	0	0	0	109.3	S395	S395-S403 VanDerWaalsContact OG-CB 3.31Å; S395-S403 WeakPolarHBondContact OG-CB 3.48Å
404	S	63.3	Low	74.9	Confident	17 Å²	17	53.5 Å²	53.5	12%	0.119	30%	0.297	C	S	.	.	B	Isolated β-bridge	trans	-89.6	118.6	168.7	163.8	0	0	0	0	105.9	K406 D407 C414	S404-K406 PolarHBondContact O-N 3.43Å; S404-D407 WeakPolarHBondContact CB-OD1 3.2Å; S404-D407 CarbonylContact O-C 3.5Å; S404-D407 PolarHBondContact O-N 2.98Å; S404-D407 VanDerWaalsContact O-O 3.04Å; S404-D407 PolarHBondContact OG-OD1 3.16Å; S404-C414 PolarHBondContact N-SG 3.46Å
405	H	63.1	Low	74.8	Confident	73 Å²	73	55.1 Å²	55.1	34%	0.338	31%	0.309	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.7	7.1	-179.4	-60.5	-74.5	0	0	0	113.7	A22 K397	A22-H405 VanDerWaalsContact CB-O 3.26Å; A22-H405 WeakPolarHBondContact CB-O 3.4Å; K397-H405 WeakPolarHBondContact CA-NE2 3.49Å; K397-H405 WeakPolarHBondContact CB-NE2 3.43Å
406	K	58.5	Low	75	Confident	170 Å²	170	53.3 Å²	53.3	74%	0.739	30%	0.296	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.9	-27	175.1	-60.7	-176.7	178.1	-177.2	0	111.8	A22 S404	A22-K406 VanDerWaalsContact CB-O 3.31Å; A22-K406 WeakPolarHBondContact CB-O 3.4Å; A22-K406 PolarHBondContact N-O 2.95Å; S404-K406 PolarHBondContact O-N 3.43Å
407	D	61.9	Low	75.5	Confident	32 Å²	32	50 Å²	50	17%	0.171	28%	0.278	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-147.8	108.8	-177.5	51.1	-20.2	0	0	0	110.7	Q20 S404 G409 N410	Q20-D407 CarbonylContact O-C 3.07Å; Q20-D407 WeakPolarHBondContact O-CA 3.38Å; S404-D407 WeakPolarHBondContact CB-OD1 3.2Å; S404-D407 CarbonylContact O-C 3.5Å; S404-D407 PolarHBondContact O-N 2.98Å; S404-D407 VanDerWaalsContact O-O 3.04Å; S404-D407 PolarHBondContact OG-OD1 3.16Å; D407-G409 PolarHBondContact O-N 2.96Å; D407-N410 HydrophobicContact CB-CB 4.15Å; D407-N410 VanDerWaalsContact OD2-CB 3.24Å; D407-N410 WeakPolarHBondContact OD2-CB 3.43Å; D407-N410 VanDerWaalsContact OD2-CG 3.28Å; D407-N410 PolarHBondContact OD2-ND2 3.21Å
408	F	61.5	Low	76.3	Confident	75 Å²	75	47.6 Å²	47.6	33%	0.329	27%	0.265	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-70.6	122.6	178.5	-78.1	-83.9	0	0	0	109.9	V19 Q20 A22 M25 N410	V19-F408 CarbonylContact C-O 3.51Å; V19-F408 WeakPolarHBondContact CA-O 3.44Å; Q20-F408 PolarHBondContact N-O 3.23Å; Q20-F408 PolarHBondContact O-N 3.09Å; A22-F408 HydrophobicContact CB-CD2 4.43Å; A22-F408 HydrophobicContact CB-CE2 4.19Å; M25-F408 HydrophobicContact CE-CE2 4.45Å; M25-F408 HydrophobicContact CE-CZ 4.41Å; M25-F408 HydrophobicContact CG-CD2 4.16Å; M25-F408 HydrophobicContact CG-CE2 4Å; F408-N410 VanDerWaalsContact C-N 3.32Å; F408-N410 PolarHBondContact O-N 2.99Å
409	G	62.8	Low	76.9	Confident	34 Å²	34	42.4 Å²	42.4	35%	0.351	23%	0.229	S	C	.	.	T	Hydrogen-bonded Turn	trans	83.7	-3.3	170.2	0	0	0	0	0	116.3	P18 D407	P18-G409 CarbonylContact O-C 3.37Å; P18-G409 VanDerWaalsContact O-C 3.29Å; P18-G409 WeakPolarHBondContact O-CA 3.28Å; D407-G409 PolarHBondContact O-N 2.96Å
410	N	75.9	Confident	77.6	Confident	16 Å²	16	39.1 Å²	39.1	9%	0.086	21%	0.212	C	C	.	.			trans	-88.1	122.2	163.8	-177.5	8.6	0	0	0	110	V19 D407 F408 N412	V19-N410 HydrophobicContact CG1-CB 3.99Å; D407-N410 HydrophobicContact CB-CB 4.15Å; D407-N410 VanDerWaalsContact OD2-CB 3.24Å; D407-N410 WeakPolarHBondContact OD2-CB 3.43Å; D407-N410 VanDerWaalsContact OD2-CG 3.28Å; D407-N410 PolarHBondContact OD2-ND2 3.21Å; F408-N410 VanDerWaalsContact C-N 3.32Å; F408-N410 PolarHBondContact O-N 2.99Å; N410-N412 VanDerWaalsContact C-N 3.32Å; N410-N412 WeakPolarHBondContact OD1-CB 3.18Å; N410-N412 PolarHBondContact OD1-N 3.29Å; N410-N412 PolarHBondContact OD1-ND2 3.16Å
411	I	83.4	Confident	78.6	Confident	2 Å²	2	41.8 Å²	41.8	1%	0.01	22%	0.217	C	C	.	.			trans	-87	-0.9	180	65.9	173	0	0	0	113.4	L223 H227 R309 G413 C414 L416	L223-I411 HydrophobicContact CD1-CG2 4.45Å; L223-I411 HydrophobicContact CD2-CG2 3.58Å; L223-I411 HydrophobicContact CG-CG2 3.93Å; H227-I411 HydrophobicContact CB-CD1 3.9Å; H227-I411 HydrophobicContact CB-CG1 4.1Å; R309-I411 PolarHBondContact NH2-O 3.16Å; I411-G413 VanDerWaalsContact C-N 3.33Å; I411-G413 PolarHBondContact O-N 2.75Å; I411-C414 WeakPolarHBondContact O-CB 3.34Å; I411-C414 PolarHBondContact O-N 2.56Å; I411-C414 VanDerWaalsContact O-N 3.17Å; I411-L416 HydrophobicContact CD1-CD2 3.97Å
412	N	84.9	Confident	79.2	Confident	21 Å²	21	41.1 Å²	41.1	11%	0.112	22%	0.219	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.6	-32.3	-177.4	-67.4	-20.1	0	0	0	113.2	R309 V313 T318 H329 N410 C414	R309-N412 PolarHBondContact NH1-OD1 3.17Å; V313-N412 HydrophobicContact CG1-CB 4.07Å; T318-N412 WeakPolarHBondContact CG2-ND2 3.46Å; H329-N412 PolarHBondContact O-ND2 3.11Å; N410-N412 VanDerWaalsContact C-N 3.32Å; N410-N412 WeakPolarHBondContact OD1-CB 3.18Å; N410-N412 PolarHBondContact OD1-N 3.29Å; N410-N412 PolarHBondContact OD1-ND2 3.16Å; N412-C414 VanDerWaalsContact C-N 3.27Å
413	G	78.1	Confident	80.3	Confident	52 Å²	52	39.6 Å²	39.6	54%	0.536	21%	0.212	S	C	.	.	T	Hydrogen-bonded Turn	trans	-82.9	-0.9	174.4	0	0	0	0	0	114.2	I411	I411-G413 VanDerWaalsContact C-N 3.33Å; I411-G413 PolarHBondContact O-N 2.75Å
414	C	83.9	Confident	81.7	Confident	4 Å²	4	39.2 Å²	39.2	3%	0.027	21%	0.21	C	C	.	.	S	Bend	trans	-108.2	164	-171	-57.7	0	0	0	0	112.2	W401 M402 S404 I411 N412	W401-C414 WeakPolarHBondContact O-CB 3.44Å; M402-C414 VanDerWaalsContact C-SG 3.59Å; S404-C414 PolarHBondContact N-SG 3.46Å; I411-C414 WeakPolarHBondContact O-CB 3.34Å; I411-C414 PolarHBondContact O-N 2.56Å; I411-C414 VanDerWaalsContact O-N 3.17Å; N412-C414 VanDerWaalsContact C-N 3.27Å
415	S	86.8	Confident	83.4	Confident	40 Å²	40	40.6 Å²	40.6	28%	0.28	23%	0.226	S	C	.	.			trans	-109.3	57.5	176.8	-62	0	0	0	0	111.6	W401 H417 Y418	W401-S415 CarbonylContact O-C 3.21Å; W401-S415 PolarHBondContact O-N 3.45Å; W401-S415 VanDerWaalsContact O-N 3.17Å; S415-H417 PolarHBondContact O-N 3.27Å; S415-H417 VanDerWaalsContact O-N 3.15Å; S415-Y418 PolarHBondContact O-N 3.29Å; S415-Y418 VanDerWaalsContact O-N 3.09Å
416	L	89.6	Confident	85	Confident	0 Å²	0	39.6 Å²	39.6	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-58.8	-28.1	-177.7	177	62	0	0	0	112.8	E306 W401 M402 I411 Y418 Y419 F420	E306-L416 HydrophobicContact CG-CB 3.88Å; E306-L416 HydrophobicContact CG-CD2 4.36Å; E306-L416 HydrophobicContact CG-CG 4.16Å; W401-L416 PolarHBondContact O-N 3.18Å; M402-L416 HydrophobicContact SD-CD1 3.62Å; I411-L416 HydrophobicContact CD1-CD2 3.97Å; L416-Y418 PolarHBondContact O-N 3.28Å; L416-Y419 HydrophobicContact CD1-CD1 4.1Å; L416-Y419 WeakPolarHBondContact O-CB 3.49Å; L416-Y419 PolarHBondContact O-N 3.06Å; L416-F420 HydrophobicContact CD1-CE2 4.36Å; L416-F420 HydrophobicContact CD1-CZ 4.19Å; L416-F420 HydrophobicContact CD2-CE2 3.89Å; L416-F420 HydrophobicContact CD2-CZ 3.97Å; L416-F420 HydrophobicContact CG-CD2 4.29Å; L416-F420 HydrophobicContact CG-CE2 3.73Å; L416-F420 HydrophobicContact CG-CZ 3.98Å; L416-F420 PolarHBondContact O-N 2.96Å
417	H	92.9	Very high	86.9	Confident	25 Å²	25	31.5 Å²	31.5	12%	0.116	19%	0.188	C	C	.	.	H	α-helix	trans	-57.4	-35.9	176.4	57.9	-85.9	0	0	0	112.6	E306 L310 S415 Y419 F420 F421	E306-H417 HydrophobicContact CB-CB 3.91Å; E306-H417 HydrophobicContact CG-CB 3.92Å; L310-H417 WeakPolarHBondContact CD1-ND1 3.24Å; S415-H417 PolarHBondContact O-N 3.27Å; S415-H417 VanDerWaalsContact O-N 3.15Å; H417-Y419 VanDerWaalsContact C-N 3.32Å; H417-Y419 PolarHBondContact O-N 3.44Å; H417-F420 PolarHBondContact O-N 3.45Å; H417-F421 HydrophobicContact CB-CD2 4.48Å; H417-F421 HydrophobicContact CB-CE2 4.23Å; H417-F421 WeakPolarHBondContact O-CD2 3.38Å; H417-F421 PolarHBondContact O-N 3.38Å
418	Y	93.4	Very high	88.6	Confident	116 Å²	116	31 Å²	31	46%	0.455	19%	0.19	S	C	.	.	H	α-helix	trans	-64.9	-35.7	176.4	-67	-45.5	0	0	0	112.7	W401 S415 L416 F421 L422	W401-Y418 HydrophobicContact CD2-CD2 4.36Å; W401-Y418 HydrophobicContact CD2-CG 4.46Å; W401-Y418 HydrophobicContact CG-CD2 4.49Å; W401-Y418 HydrophobicContact CZ2-CD2 4.46Å; W401-Y418 HydrophobicContact CZ2-CG 4.36Å; W401-Y418 AromaticContact NE1-CD2 3.93Å; S415-Y418 PolarHBondContact O-N 3.29Å; S415-Y418 VanDerWaalsContact O-N 3.09Å; L416-Y418 PolarHBondContact O-N 3.28Å; Y418-F421 PolarHBondContact O-N 2.87Å; Y418-L422 VanDerWaalsContact O-CB 3.28Å; Y418-L422 WeakPolarHBondContact O-CB 2.95Å; Y418-L422 PolarHBondContact O-N 2.96Å
419	Y	93.2	Very high	90.2	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-63.7	-43.5	175	175.8	-108.3	0	0	0	111.3	Q216 T220 G387 L390 L391 V394 L416 H417 L422 L423	Q216-Y419 PolarHBondContact NE2-OH 2.98Å; Q216-Y419 VanDerWaalsContact NE2-OH 3.15Å; Q216-Y419 PolarHBondContact OE1-OH 2.88Å; T220-Y419 HydrophobicContact CG2-CD1 4.44Å; T220-Y419 HydrophobicContact CG2-CE1 3.9Å; G387-Y419 PolarHBondContact O-OH 3.35Å; L390-Y419 HydrophobicContact CD2-CE2 4.22Å; L390-Y419 HydrophobicContact CG-CE2 4.14Å; L391-Y419 HydrophobicContact CB-CE2 4.29Å; L391-Y419 HydrophobicContact CD1-CD1 4.15Å; L391-Y419 HydrophobicContact CD1-CD2 4.33Å; L391-Y419 HydrophobicContact CD1-CE1 3.83Å; L391-Y419 HydrophobicContact CD1-CE2 4.01Å; L391-Y419 HydrophobicContact CD1-CG 4.38Å; V394-Y419 HydrophobicContact CG1-CD2 4.38Å; V394-Y419 HydrophobicContact CG2-CD2 3.74Å; V394-Y419 HydrophobicContact CG2-CE2 4.27Å; V394-Y419 HydrophobicContact CG2-CG 4.4Å; L416-Y419 HydrophobicContact CD1-CD1 4.1Å; L416-Y419 WeakPolarHBondContact O-CB 3.49Å; L416-Y419 PolarHBondContact O-N 3.06Å; H417-Y419 VanDerWaalsContact C-N 3.32Å; H417-Y419 PolarHBondContact O-N 3.44Å; Y419-L422 WeakPolarHBondContact O-CB 3.39Å; Y419-L422 PolarHBondContact O-N 3.26Å; Y419-L423 HydrophobicContact CD1-CD1 4.02Å; Y419-L423 HydrophobicContact CE1-CD1 3.45Å; Y419-L423 VanDerWaalsContact CE1-CD1 3.45Å; Y419-L423 HydrophobicContact CE1-CG 4.22Å; Y419-L423 HydrophobicContact CE2-CD1 4.32Å; Y419-L423 HydrophobicContact CE2-CD2 4.38Å; Y419-L423 HydrophobicContact CE2-CG 4.25Å; Y419-L423 WeakPolarHBondContact O-CG 3.33Å; Y419-L423 PolarHBondContact O-N 3.36Å
420	F	95.6	Very high	91.8	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-64.6	-41.5	176.3	-66.4	-38.8	0	0	0	112.9	T220 Y221 A302 E306 L416 H417 L423 A424	T220-F420 WeakPolarHBondContact OG1-CE1 3.24Å; Y221-F420 AromaticContact CD1-CE1 3.77Å; Y221-F420 HydrophobicContact CD1-CE1 3.77Å; Y221-F420 AromaticContact CD1-CZ 4Å; Y221-F420 HydrophobicContact CD1-CZ 4Å; Y221-F420 HydrophobicContact CE1-CD1 4.08Å; Y221-F420 AromaticContact CE1-CE1 3.62Å; Y221-F420 HydrophobicContact CE1-CE1 3.62Å; Y221-F420 HydrophobicContact CE1-CZ 4.15Å; A302-F420 HydrophobicContact CB-CB 4.46Å; A302-F420 HydrophobicContact CB-CD1 4.24Å; A302-F420 HydrophobicContact CB-CD2 3.89Å; A302-F420 HydrophobicContact CB-CE1 4.46Å; A302-F420 HydrophobicContact CB-CE2 4.11Å; A302-F420 HydrophobicContact CB-CG 3.96Å; A302-F420 HydrophobicContact CB-CZ 4.39Å; A302-F420 WeakPolarHBondContact O-CD2 3.47Å; E306-F420 HydrophobicContact CB-CD2 4.1Å; E306-F420 HydrophobicContact CB-CE2 4.17Å; E306-F420 HydrophobicContact CG-CE2 4.44Å; L416-F420 HydrophobicContact CD1-CE2 4.36Å; L416-F420 HydrophobicContact CD1-CZ 4.19Å; L416-F420 HydrophobicContact CD2-CE2 3.89Å; L416-F420 HydrophobicContact CD2-CZ 3.97Å; L416-F420 HydrophobicContact CG-CD2 4.29Å; L416-F420 HydrophobicContact CG-CE2 3.73Å; L416-F420 HydrophobicContact CG-CZ 3.98Å; L416-F420 PolarHBondContact O-N 2.96Å; H417-F420 PolarHBondContact O-N 3.45Å; F420-L423 PolarHBondContact O-N 3.46Å; F420-A424 PolarHBondContact O-N 2.81Å
421	F	97.2	Very high	92.7	Very high	77 Å²	77	32.4 Å²	32.4	34%	0.338	19%	0.193	S	C	.	.	H	α-helix	trans	-67.6	-34.4	174.6	-69.2	-56.4	0	0	0	112.8	V300 I304 H417 Y418 A424 G425	V300-F421 HydrophobicContact CG1-CE1 4.47Å; I304-F421 HydrophobicContact CG1-CE1 4.46Å; I304-F421 HydrophobicContact CG1-CZ 4.3Å; H417-F421 HydrophobicContact CB-CD2 4.48Å; H417-F421 HydrophobicContact CB-CE2 4.23Å; H417-F421 WeakPolarHBondContact O-CD2 3.38Å; H417-F421 PolarHBondContact O-N 3.38Å; Y418-F421 PolarHBondContact O-N 2.87Å; F421-A424 PolarHBondContact O-N 3.46Å; F421-G425 PolarHBondContact O-N 3.01Å
422	L	96.3	Very high	93.3	Very high	59 Å²	59	37.3 Å²	37.3	31%	0.309	22%	0.219	S	C	.	.	H	α-helix	trans	-62.1	-47.3	172.8	175.9	64.1	0	0	0	111.1	L390 V394 W401 Y418 Y419 A424 G425 I426	L390-L422 HydrophobicContact CD1-CD2 4.16Å; L390-L422 HydrophobicContact CD2-CD2 4.14Å; L390-L422 HydrophobicContact CG-CD2 4.4Å; V394-L422 HydrophobicContact CG1-CD2 4.35Å; W401-L422 HydrophobicContact CZ3-CB 4.22Å; W401-L422 HydrophobicContact CZ3-CD2 3.98Å; Y418-L422 VanDerWaalsContact O-CB 3.28Å; Y418-L422 WeakPolarHBondContact O-CB 2.95Å; Y418-L422 PolarHBondContact O-N 2.96Å; Y419-L422 WeakPolarHBondContact O-CB 3.39Å; Y419-L422 PolarHBondContact O-N 3.26Å; L422-A424 VanDerWaalsContact C-N 3.32Å; L422-A424 PolarHBondContact O-N 3.49Å; L422-G425 PolarHBondContact O-N 3.25Å; L422-G425 VanDerWaalsContact O-N 3.15Å; L422-I426 HydrophobicContact CD1-CD1 4.16Å; L422-I426 HydrophobicContact CD1-CG1 4.33Å; L422-I426 HydrophobicContact CG-CD1 4.02Å; L422-I426 WeakPolarHBondContact O-CG1 3.28Å; L422-I426 PolarHBondContact O-N 3.43Å
423	L	96.4	Very high	93.6	Very high	2 Å²	2	40 Å²	40	1%	0.01	24%	0.236	C	C	.	.	H	α-helix	trans	-59.5	-43.3	175.2	-73.2	178.5	0	0	0	112	M212 V213 Q216 A299 L390 Y419 F420 G425 I426 Q427	M212-L423 HydrophobicContact CG-CD2 4.05Å; M212-L423 HydrophobicContact SD-CD2 3.75Å; V213-L423 HydrophobicContact CG2-CB 4.09Å; V213-L423 HydrophobicContact CG2-CD2 4.39Å; Q216-L423 HydrophobicContact CG-CD1 3.52Å; A299-L423 HydrophobicContact CB-CB 4.47Å; L390-L423 HydrophobicContact CD2-CD2 3.99Å; Y419-L423 HydrophobicContact CD1-CD1 4.02Å; Y419-L423 HydrophobicContact CE1-CD1 3.45Å; Y419-L423 VanDerWaalsContact CE1-CD1 3.45Å; Y419-L423 HydrophobicContact CE1-CG 4.22Å; Y419-L423 HydrophobicContact CE2-CD1 4.32Å; Y419-L423 HydrophobicContact CE2-CD2 4.38Å; Y419-L423 HydrophobicContact CE2-CG 4.25Å; Y419-L423 WeakPolarHBondContact O-CG 3.33Å; Y419-L423 PolarHBondContact O-N 3.36Å; F420-L423 PolarHBondContact O-N 3.46Å; L423-G425 VanDerWaalsContact C-N 3.33Å; L423-G425 PolarHBondContact O-N 3.3Å; L423-I426 PolarHBondContact O-N 3.15Å; L423-Q427 VanDerWaalsContact O-CB 3.3Å; L423-Q427 WeakPolarHBondContact O-CB 3.26Å; L423-Q427 PolarHBondContact O-N 3.17Å
424	A	97.6	Very high	94.3	Very high	9 Å²	9	38 Å²	38	7%	0.074	21%	0.213	C	C	.	.	H	α-helix	trans	-60.4	-41.7	174	0	0	0	0	0	112	M296 A299 V300 F420 F421 L422 Q427 G428	M296-A424 HydrophobicContact CG-CB 4.49Å; A299-A424 HydrophobicContact CB-CB 3.86Å; V300-A424 HydrophobicContact CG2-CB 3.63Å; F420-A424 PolarHBondContact O-N 2.81Å; F421-A424 PolarHBondContact O-N 3.46Å; L422-A424 VanDerWaalsContact C-N 3.32Å; L422-A424 PolarHBondContact O-N 3.49Å; A424-Q427 PolarHBondContact O-N 3.29Å; A424-G428 PolarHBondContact O-N 3.03Å
425	G	97.8	Very high	94.6	Very high	46 Å²	46	41.5 Å²	41.5	47%	0.474	23%	0.231	S	C	.	.	H	α-helix	trans	-64.9	-46.9	177.4	0	0	0	0	0	113.1	F421 L422 L423 Q427 G428 L429	F421-G425 PolarHBondContact O-N 3.01Å; L422-G425 PolarHBondContact O-N 3.25Å; L422-G425 VanDerWaalsContact O-N 3.15Å; L423-G425 VanDerWaalsContact C-N 3.33Å; L423-G425 PolarHBondContact O-N 3.3Å; G425-Q427 VanDerWaalsContact C-N 3.3Å; G425-Q427 PolarHBondContact O-N 2.84Å; G425-G428 PolarHBondContact O-N 3.4Å; G425-L429 PolarHBondContact O-N 3.04Å
426	I	97.3	Very high	94.6	Very high	51 Å²	51	43.8 Å²	43.8	26%	0.262	24%	0.239	S	C	.	.	H	α-helix	trans	-58.7	-45.6	175.6	-67.4	168.8	0	0	0	110	P209 L390 L422 L423 T430	P209-I426 HydrophobicContact CB-CG2 4.1Å; L390-I426 HydrophobicContact CD2-CD1 3.78Å; L422-I426 HydrophobicContact CD1-CD1 4.16Å; L422-I426 HydrophobicContact CD1-CG1 4.33Å; L422-I426 HydrophobicContact CG-CD1 4.02Å; L422-I426 WeakPolarHBondContact O-CG1 3.28Å; L422-I426 PolarHBondContact O-N 3.43Å; L423-I426 PolarHBondContact O-N 3.15Å; I426-T430 WeakPolarHBondContact O-CB 3.43Å; I426-T430 PolarHBondContact O-N 2.86Å; I426-T430 PolarHBondContact O-OG1 3.04Å
427	Q	97.7	Very high	94.4	Very high	0 Å²	0	47.8 Å²	47.8	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-66.9	-39.2	178.3	-175.9	61.3	20	0	0	112.6	P209 Y210 V213 M292 V295 M296 L423 A424 G425 T430 L431	P209-Q427 PolarHBondContact O-OE1 2.86Å; Y210-Q427 VanDerWaalsContact N-OE1 3.13Å; V213-Q427 HydrophobicContact CG2-CB 4.09Å; M292-Q427 PolarHBondContact O-NE2 2.97Å; V295-Q427 HydrophobicContact CG1-CG 3.59Å; M296-Q427 HydrophobicContact CB-CB 4.31Å; M296-Q427 HydrophobicContact CB-CG 3.81Å; L423-Q427 VanDerWaalsContact O-CB 3.3Å; L423-Q427 WeakPolarHBondContact O-CB 3.26Å; L423-Q427 PolarHBondContact O-N 3.17Å; A424-Q427 PolarHBondContact O-N 3.29Å; G425-Q427 VanDerWaalsContact C-N 3.3Å; G425-Q427 PolarHBondContact O-N 2.84Å; Q427-T430 WeakPolarHBondContact O-CB 3.4Å; Q427-T430 PolarHBondContact O-N 2.9Å; Q427-L431 WeakPolarHBondContact O-CB 3.35Å; Q427-L431 PolarHBondContact O-N 3.17Å
428	G	97.4	Very high	93.9	Very high	22 Å²	22	46.8 Å²	46.8	23%	0.227	26%	0.259	C	S	.	.	H	α-helix	trans	-64.1	-42.6	177.3	0	0	0	0	0	112.6	A424 G425 T430 L431 L432	A424-G428 PolarHBondContact O-N 3.03Å; G425-G428 PolarHBondContact O-N 3.4Å; G428-T430 VanDerWaalsContact C-N 3.33Å; G428-T430 PolarHBondContact O-N 3.03Å; G428-L431 PolarHBondContact O-N 2.92Å; G428-L432 PolarHBondContact O-N 2.8Å
429	L	96.7	Very high	93.3	Very high	114 Å²	114	44.5 Å²	44.5	60%	0.597	26%	0.257	S	S	*	.	H	α-helix	trans	-62.2	-42.6	173.1	179.8	62.3	0	0	0	111.3	G425 L432 V433	G425-L429 PolarHBondContact O-N 3.04Å; L429-L432 WeakPolarHBondContact O-CB 3.33Å; L429-L432 PolarHBondContact O-N 3.17Å; L429-V433 WeakPolarHBondContact O-CG2 3.27Å; L429-V433 PolarHBondContact O-N 3.21Å; L429-V433 VanDerWaalsContact O-N 3.07Å
430	T	95.7	Very high	92.7	Very high	23 Å²	23	51 Å²	51	14%	0.141	29%	0.285	C	S	.	.	H	α-helix	trans	-62.6	-44.4	177.7	-56.9	0	0	0	0	111.3	A206 P209 I426 Q427 G428 L432 V433 F434	A206-T430 VanDerWaalsContact O-CG2 3.3Å; A206-T430 WeakPolarHBondContact O-CG2 3.4Å; P209-T430 HydrophobicContact CB-CG2 4.05Å; P209-T430 WeakPolarHBondContact CB-OG1 3.34Å; P209-T430 HydrophobicContact CG-CG2 3.82Å; P209-T430 VanDerWaalsContact CG-OG1 3.3Å; P209-T430 WeakPolarHBondContact CG-OG1 3.5Å; I426-T430 WeakPolarHBondContact O-CB 3.43Å; I426-T430 PolarHBondContact O-N 2.86Å; I426-T430 PolarHBondContact O-OG1 3.04Å; Q427-T430 WeakPolarHBondContact O-CB 3.4Å; Q427-T430 PolarHBondContact O-N 2.9Å; G428-T430 VanDerWaalsContact C-N 3.33Å; G428-T430 PolarHBondContact O-N 3.03Å; T430-L432 VanDerWaalsContact C-N 3.34Å; T430-L432 PolarHBondContact O-N 3.01Å; T430-V433 PolarHBondContact O-N 3.41Å; T430-F434 WeakPolarHBondContact O-CB 3.44Å; T430-F434 PolarHBondContact O-N 2.72Å
431	L	95.9	Very high	91.8	Very high	18 Å²	18	56.1 Å²	56.1	9%	0.094	31%	0.305	C	S	.	.	H	α-helix	trans	-58.5	-45	175.7	173.5	63.4	0	0	0	111.3	A289 M292 F293 Q427 G428 F434 L435	A289-L431 HydrophobicContact CB-CD1 4.11Å; A289-L431 VanDerWaalsContact O-CD1 3.3Å; A289-L431 WeakPolarHBondContact O-CD1 3.29Å; M292-L431 HydrophobicContact CB-CD1 3.92Å; F293-L431 HydrophobicContact CB-CD2 3.88Å; F293-L431 HydrophobicContact CD2-CD2 4.05Å; F293-L431 HydrophobicContact CG-CD2 4.49Å; Q427-L431 WeakPolarHBondContact O-CB 3.35Å; Q427-L431 PolarHBondContact O-N 3.17Å; G428-L431 PolarHBondContact O-N 2.92Å; L431-F434 PolarHBondContact O-N 3.38Å; L431-L435 HydrophobicContact CD1-CD1 3.99Å; L431-L435 HydrophobicContact CD1-CG 4.03Å; L431-L435 HydrophobicContact CG-CD1 4.04Å; L431-L435 HydrophobicContact CG-CG 4.47Å; L431-L435 WeakPolarHBondContact O-CB 3.42Å; L431-L435 VanDerWaalsContact O-CG 3.28Å; L431-L435 WeakPolarHBondContact O-CG 3.39Å; L431-L435 PolarHBondContact O-N 3.02Å
432	L	94.2	Very high	90.7	Very high	104 Å²	104	54.2 Å²	54.2	55%	0.545	30%	0.299	S	S	.	.	H	α-helix	trans	-58.9	-51.1	177.7	-173.1	98.2	0	0	0	111.2	G428 L429 T430 F434 L435 I436	G428-L432 PolarHBondContact O-N 2.8Å; L429-L432 WeakPolarHBondContact O-CB 3.33Å; L429-L432 PolarHBondContact O-N 3.17Å; T430-L432 VanDerWaalsContact C-N 3.34Å; T430-L432 PolarHBondContact O-N 3.01Å; L432-F434 VanDerWaalsContact C-N 3.33Å; L432-F434 PolarHBondContact O-N 2.93Å; L432-L435 PolarHBondContact O-N 2.79Å; L432-I436 HydrophobicContact CD2-CD1 4.41Å; L432-I436 HydrophobicContact CG-CD1 4.32Å; L432-I436 WeakPolarHBondContact O-CG1 3.42Å; L432-I436 PolarHBondContact O-N 3.32Å; L432-I436 VanDerWaalsContact O-N 3.12Å
433	V	92	Very high	89.7	Confident	78 Å²	78	57.6 Å²	57.6	47%	0.473	31%	0.311	S	S	.	.	H	α-helix	trans	-60.9	-44.7	178.3	174.1	0	0	0	0	110.6	L429 T430 L435 I436 V437	L429-V433 WeakPolarHBondContact O-CG2 3.27Å; L429-V433 PolarHBondContact O-N 3.21Å; L429-V433 VanDerWaalsContact O-N 3.07Å; T430-V433 PolarHBondContact O-N 3.41Å; V433-L435 PolarHBondContact O-N 2.82Å; V433-I436 PolarHBondContact O-N 3.48Å; V433-V437 HydrophobicContact CG1-CG2 4.46Å; V433-V437 WeakPolarHBondContact O-CG2 3.13Å; V433-V437 PolarHBondContact O-N 3.4Å
434	F	92	Very high	88.5	Confident	10 Å²	10	63.9 Å²	63.9	4%	0.044	34%	0.34	C	S	.	.	H	α-helix	trans	-64.1	-39.9	-179	-169.9	-99.4	0	0	0	112.3	V203 A206 L285 I288 A289 M292 T430 L431 L432 V437 S438	V203-F434 HydrophobicContact CG1-CE2 4.25Å; A206-F434 HydrophobicContact CB-CD2 3.64Å; A206-F434 HydrophobicContact CB-CE2 4.09Å; L285-F434 HydrophobicContact CD2-CZ 4.08Å; L285-F434 WeakPolarHBondContact O-CE1 3.35Å; I288-F434 HydrophobicContact CB-CE1 3.98Å; I288-F434 HydrophobicContact CB-CZ 4.01Å; I288-F434 HydrophobicContact CG2-CE1 3.74Å; I288-F434 HydrophobicContact CG2-CE2 4.47Å; I288-F434 HydrophobicContact CG2-CZ 3.61Å; A289-F434 HydrophobicContact CB-CD1 3.93Å; A289-F434 HydrophobicContact CB-CE1 4.11Å; M292-F434 HydrophobicContact CE-CD1 4.31Å; M292-F434 HydrophobicContact CE-CD2 3.98Å; M292-F434 HydrophobicContact CE-CE2 4.19Å; M292-F434 HydrophobicContact CE-CG 4.03Å; M292-F434 HydrophobicContact CE-CZ 4.45Å; M292-F434 HydrophobicContact SD-CB 3.99Å; M292-F434 HydrophobicContact SD-CD1 3.81Å; M292-F434 HydrophobicContact SD-CD2 4.37Å; M292-F434 HydrophobicContact SD-CE1 4.37Å; M292-F434 HydrophobicContact SD-CG 3.8Å; T430-F434 WeakPolarHBondContact O-CB 3.44Å; T430-F434 PolarHBondContact O-N 2.72Å; L431-F434 PolarHBondContact O-N 3.38Å; L432-F434 VanDerWaalsContact C-N 3.33Å; L432-F434 PolarHBondContact O-N 2.93Å; F434-V437 PolarHBondContact O-N 2.87Å; F434-S438 VanDerWaalsContact O-CB 3.24Å; F434-S438 WeakPolarHBondContact O-CB 3.04Å; F434-S438 PolarHBondContact O-N 3.47Å
435	L	90.8	Very high	87.2	Confident	78 Å²	78	70.3 Å²	70.3	41%	0.408	37%	0.366	S	S	.	.	H	α-helix	trans	-62.6	-44.7	174	-75.8	171.3	0	0	0	111.8	A289 L431 L432 V433 V437 S438 V439	A289-L435 HydrophobicContact CB-CD2 3.66Å; A289-L435 HydrophobicContact CB-CG 4.35Å; L431-L435 HydrophobicContact CD1-CD1 3.99Å; L431-L435 HydrophobicContact CD1-CG 4.03Å; L431-L435 HydrophobicContact CG-CD1 4.04Å; L431-L435 HydrophobicContact CG-CG 4.47Å; L431-L435 WeakPolarHBondContact O-CB 3.42Å; L431-L435 VanDerWaalsContact O-CG 3.28Å; L431-L435 WeakPolarHBondContact O-CG 3.39Å; L431-L435 PolarHBondContact O-N 3.02Å; L432-L435 PolarHBondContact O-N 2.79Å; V433-L435 PolarHBondContact O-N 2.82Å; L435-V437 VanDerWaalsContact C-N 3.33Å; L435-V437 PolarHBondContact O-N 3.36Å; L435-S438 PolarHBondContact O-N 2.72Å; L435-V439 VanDerWaalsContact O-CG2 3.32Å; L435-V439 WeakPolarHBondContact O-CG2 3.35Å; L435-V439 PolarHBondContact O-N 2.92Å
436	I	87.6	Confident	85.7	Confident	88 Å²	88	71.5 Å²	71.5	45%	0.451	37%	0.367	S	S	.	.	H	α-helix	trans	-59.5	-45.7	177.1	-66.6	165.1	0	0	0	110.5	L432 V433 K440	L432-I436 HydrophobicContact CD2-CD1 4.41Å; L432-I436 HydrophobicContact CG-CD1 4.32Å; L432-I436 WeakPolarHBondContact O-CG1 3.42Å; L432-I436 PolarHBondContact O-N 3.32Å; L432-I436 VanDerWaalsContact O-N 3.12Å; V433-I436 PolarHBondContact O-N 3.48Å; I436-K440 WeakPolarHBondContact O-CG 3.35Å; I436-K440 PolarHBondContact O-N 3.43Å
437	V	84.4	Confident	84.1	Confident	83 Å²	83	77.8 Å²	77.8	50%	0.503	39%	0.388	S	S	.	.	H	α-helix	trans	-66.9	-44.6	178.8	173.8	0	0	0	0	111.1	V433 F434 L435 V439 K440 Y441	V433-V437 HydrophobicContact CG1-CG2 4.46Å; V433-V437 WeakPolarHBondContact O-CG2 3.13Å; V433-V437 PolarHBondContact O-N 3.4Å; F434-V437 PolarHBondContact O-N 2.87Å; L435-V437 VanDerWaalsContact C-N 3.33Å; L435-V437 PolarHBondContact O-N 3.36Å; V437-V439 VanDerWaalsContact C-N 3.35Å; V437-V439 PolarHBondContact O-N 2.7Å; V437-K440 PolarHBondContact O-N 2.82Å; V437-Y441 WeakPolarHBondContact O-CB 3.5Å; V437-Y441 PolarHBondContact O-N 2.97Å
438	S	82.8	Confident	82.5	Confident	4 Å²	4	80.2 Å²	80.2	3%	0.028	41%	0.408	C	S	.	.	H	α-helix	trans	-60.8	-42.4	179.6	180	0	0	0	0	111.9	L285 F434 L435 Y441 D442	L285-S438 WeakPolarHBondContact CB-OG 3.37Å; F434-S438 VanDerWaalsContact O-CB 3.24Å; F434-S438 WeakPolarHBondContact O-CB 3.04Å; F434-S438 PolarHBondContact O-N 3.47Å; L435-S438 PolarHBondContact O-N 2.72Å; S438-Y441 PolarHBondContact O-N 3.02Å; S438-D442 PolarHBondContact O-N 3.4Å
439	V	80.4	Confident	80.7	Confident	69 Å²	69	80.8 Å²	80.8	42%	0.418	41%	0.413	S	S	.	.	H	α-helix	trans	-66	-40.6	177.8	171.1	0	0	0	0	111	L435 V437 K443	L435-V439 VanDerWaalsContact O-CG2 3.32Å; L435-V439 WeakPolarHBondContact O-CG2 3.35Å; L435-V439 PolarHBondContact O-N 2.92Å; V437-V439 VanDerWaalsContact C-N 3.35Å; V437-V439 PolarHBondContact O-N 2.7Å; V439-K443 HydrophobicContact CG1-CD 4.29Å; V439-K443 WeakPolarHBondContact O-CB 3.04Å; V439-K443 WeakPolarHBondContact O-CG 3.26Å; V439-K443 PolarHBondContact O-N 2.97Å; V439-K443 VanDerWaalsContact O-N 3.09Å
440	K	80.7	Confident	78.8	Confident	135 Å²	135	78.8 Å²	78.8	59%	0.587	41%	0.409	S	S	*	.	H	α-helix	trans	-63.5	-43	175.1	-75.7	-178.6	178.6	-179.2	0	111.5	I436 V437 K443 Q444	I436-K440 WeakPolarHBondContact O-CG 3.35Å; I436-K440 PolarHBondContact O-N 3.43Å; V437-K440 PolarHBondContact O-N 2.82Å; K440-K443 PolarHBondContact O-N 3.24Å; K440-Q444 WeakPolarHBondContact O-CG 3.43Å; K440-Q444 PolarHBondContact O-N 2.98Å
441	Y	77.4	Confident	76.6	Confident	108 Å²	108	83.9 Å²	83.9	42%	0.424	43%	0.431	S	S	.	.	H	α-helix	trans	-62.4	-48.1	178.6	-174.5	-91.1	0	0	0	112	L285 V437 S438 K443 Q444 K445	L285-Y441 HydrophobicContact CD1-CD1 3.44Å; L285-Y441 VanDerWaalsContact CD1-CD1 3.44Å; L285-Y441 HydrophobicContact CD1-CE1 3.97Å; L285-Y441 HydrophobicContact CD1-CG 3.91Å; V437-Y441 WeakPolarHBondContact O-CB 3.5Å; V437-Y441 PolarHBondContact O-N 2.97Å; S438-Y441 PolarHBondContact O-N 3.02Å; Y441-K443 VanDerWaalsContact C-N 3.33Å; Y441-K443 PolarHBondContact O-N 3.02Å; Y441-Q444 PolarHBondContact O-N 3.43Å; Y441-K445 PolarHBondContact O-N 3.4Å
442	D	73.3	Confident	74.5	Confident	38 Å²	38	93 Å²	93	20%	0.203	47%	0.465	C	S	.	.	H	α-helix	trans	-62.7	-39.2	178.2	-82.2	-8.2	0	0	0	111.7	S283 K286 S438 K445 S446	S283-D442 PolarHBondContact OG-OD2 3.08Å; K286-D442 VanDerWaalsContact CE-OD2 3.3Å; K286-D442 WeakPolarHBondContact CE-OD2 3.39Å; K286-D442 IonicContact NZ-OD2 2.7Å; S438-D442 PolarHBondContact O-N 3.4Å; D442-K445 PolarHBondContact O-N 2.94Å; D442-S446 PolarHBondContact O-N 2.86Å; D442-S446 PolarHBondContact O-OG 3.49Å
443	K	74.9	Confident	72.5	Confident	130 Å²	130	94.6 Å²	94.6	57%	0.565	47%	0.469	S	S	*	.	H	α-helix	trans	-64.7	-36.5	174.9	-77.4	-179.3	-179.8	-178	0	113	V439 K440 Y441 S446 R447	V439-K443 HydrophobicContact CG1-CD 4.29Å; V439-K443 WeakPolarHBondContact O-CB 3.04Å; V439-K443 WeakPolarHBondContact O-CG 3.26Å; V439-K443 PolarHBondContact O-N 2.97Å; V439-K443 VanDerWaalsContact O-N 3.09Å; K440-K443 PolarHBondContact O-N 3.24Å; Y441-K443 VanDerWaalsContact C-N 3.33Å; Y441-K443 PolarHBondContact O-N 3.02Å; K443-S446 PolarHBondContact O-OG 3.5Å; K443-R447 WeakPolarHBondContact O-CG 3.48Å; K443-R447 PolarHBondContact O-N 2.93Å
444	Q	71.9	Confident	70.3	Confident	134 Å²	134	100.1 Å²	100.1	63%	0.626	48%	0.481	S	S	*	.	H	α-helix	trans	-70.5	-40.8	176	-75.5	178.8	-8.2	0	0	111.4	K440 Y441 R447 A448	K440-Q444 WeakPolarHBondContact O-CG 3.43Å; K440-Q444 PolarHBondContact O-N 2.98Å; Y441-Q444 PolarHBondContact O-N 3.43Å; Q444-R447 PolarHBondContact O-N 2.78Å; Q444-A448 PolarHBondContact O-N 3.42Å
445	K	69.4	Low	68.3	Low	144 Å²	144	108.7 Å²	108.7	63%	0.626	52%	0.515	S	S	*	.	H	α-helix	trans	-63.8	-42.2	177.2	-171.3	175.9	179.8	178.1	0	112.2	Y441 D442 A448 G449	Y441-K445 PolarHBondContact O-N 3.4Å; D442-K445 PolarHBondContact O-N 2.94Å; K445-A448 PolarHBondContact O-N 3.15Å; K445-G449 PolarHBondContact O-N 2.79Å
446	S	67.6	Low	66.4	Low	70 Å²	70	109.7 Å²	109.7	49%	0.49	53%	0.528	S	S	.	.	H	α-helix	trans	-64.1	-43.6	176.9	66.6	0	0	0	0	112.1	D442 K443 A448 G449 S450	D442-S446 PolarHBondContact O-N 2.86Å; D442-S446 PolarHBondContact O-OG 3.49Å; K443-S446 PolarHBondContact O-OG 3.5Å; S446-A448 PolarHBondContact O-N 3.09Å; S446-G449 PolarHBondContact O-N 3.19Å; S446-S450 PolarHBondContact O-N 3.23Å; S446-S450 PolarHBondContact O-OG 3.3Å
447	R	63.8	Low	64.5	Low	183 Å²	183	109.9 Å²	109.9	69%	0.691	54%	0.538	S	S	*	.	H	α-helix	trans	-60.1	-43.9	175.4	-75	176.4	175.6	-175.7	-2.1	112.7	K443 Q444 G449 S450 Q451	K443-R447 WeakPolarHBondContact O-CG 3.48Å; K443-R447 PolarHBondContact O-N 2.93Å; Q444-R447 PolarHBondContact O-N 2.78Å; R447-G449 VanDerWaalsContact C-N 3.35Å; R447-S450 PolarHBondContact O-N 3.18Å; R447-Q451 PolarHBondContact O-N 3.35Å
448	A	63.8	Low	62.5	Low	52 Å²	52	113.2 Å²	113.2	43%	0.43	57%	0.565	S	S	.	*	H	α-helix	trans	-65.9	-36.8	176.9	0	0	0	0	0	112.4	Q444 K445 S446 R452	Q444-A448 PolarHBondContact O-N 3.42Å; K445-A448 PolarHBondContact O-N 3.15Å; S446-A448 PolarHBondContact O-N 3.09Å; A448-R452 PolarHBondContact O-N 2.73Å
449	G	59.6	Low	61.4	Low	33 Å²	33	118.7 Å²	118.7	34%	0.34	59%	0.591	S	S	.	*	H	α-helix	trans	-63.6	-46.2	173.6	0	0	0	0	0	112.8	K445 S446 R447 Q451 R452 Q453	K445-G449 PolarHBondContact O-N 2.79Å; S446-G449 PolarHBondContact O-N 3.19Å; R447-G449 VanDerWaalsContact C-N 3.35Å; G449-Q451 PolarHBondContact O-N 3.2Å; G449-R452 PolarHBondContact O-N 3.27Å; G449-Q453 PolarHBondContact O-N 3.03Å
450	S	57	Low	60.4	Low	72 Å²	72	121.3 Å²	121.3	50%	0.503	60%	0.601	S	S	.	*	H	α-helix	trans	-66.1	-35.1	177.1	-59.7	0	0	0	0	113.1	S446 R447 R454	S446-S450 PolarHBondContact O-N 3.23Å; S446-S450 PolarHBondContact O-OG 3.3Å; R447-S450 PolarHBondContact O-N 3.18Å; S450-R454 PolarHBondContact O-N 3.5Å
451	Q	49.5	Very low	59.3	Low	131 Å²	131	120.6 Å²	120.6	61%	0.612	60%	0.601	S	S	*	*	H	α-helix	trans	-66.6	-41.9	172.7	-86.7	-177.1	-37.5	0	0	112.2	R447 G449 R454 Y455	R447-Q451 PolarHBondContact O-N 3.35Å; G449-Q451 PolarHBondContact O-N 3.2Å; Q451-R454 PolarHBondContact O-N 3.13Å; Q451-Y455 WeakPolarHBondContact O-CD2 3.33Å; Q451-Y455 PolarHBondContact O-N 2.8Å
452	R	51.1	Low	58.2	Low	210 Å²	210	121.3 Å²	121.3	79%	0.792	61%	0.612	S	S	*	*	H	α-helix	trans	-63.6	-40.1	175.1	-93.1	-177.7	174.2	177.6	-2.2	112.9	A448 G449 Y455 S456	A448-R452 PolarHBondContact O-N 2.73Å; G449-R452 PolarHBondContact O-N 3.27Å; R452-Y455 PolarHBondContact O-N 3.36Å; R452-S456 PolarHBondContact O-N 3.11Å
453	Q	51.6	Low	57.3	Low	136 Å²	136	126.5 Å²	126.5	64%	0.636	64%	0.637	S	S	*	*	H	α-helix	trans	-64.6	-40.5	174.9	-86	-180	-39.3	0	0	112.2	G449 Y455 S456 S457	G449-Q453 PolarHBondContact O-N 3.03Å; Q453-Y455 PolarHBondContact O-N 3.47Å; Q453-S456 PolarHBondContact O-N 3.46Å; Q453-S456 PolarHBondContact O-OG 3.04Å; Q453-S457 WeakPolarHBondContact O-CB 3.48Å; Q453-S457 PolarHBondContact O-N 3.45Å; Q453-S457 VanDerWaalsContact O-N 3.15Å; Q453-S457 PolarHBondContact O-OG 2.99Å
454	R	46.6	Very low	56.1	Low	194 Å²	194	126.3 Å²	126.3	73%	0.732	64%	0.642	S	S	*	*	H	α-helix	trans	-60.2	-44.2	173.6	-97.4	-178.1	178.7	177.5	-2.5	112.2	S450 Q451 S456 S457 S458	S450-R454 PolarHBondContact O-N 3.5Å; Q451-R454 PolarHBondContact O-N 3.13Å; R454-S456 VanDerWaalsContact C-N 3.34Å; R454-S456 PolarHBondContact O-N 3.33Å; R454-S457 WeakPolarHBondContact CA-OG 3.4Å; R454-S457 PolarHBondContact O-N 3.04Å; R454-S457 PolarHBondContact O-OG 3.28Å; R454-S458 PolarHBondContact O-N 2.74Å; R454-S458 PolarHBondContact O-OG 3.3Å
455	Y	50.2	Low	55	Low	191 Å²	191	125.7 Å²	125.7	75%	0.749	64%	0.643	S	S	*	*	H	α-helix	trans	-71.1	-21.7	178.2	-93.6	-78.3	0	0	0	114.7	Q451 R452 Q453	Q451-Y455 WeakPolarHBondContact O-CD2 3.33Å; Q451-Y455 PolarHBondContact O-N 2.8Å; R452-Y455 PolarHBondContact O-N 3.36Å; Q453-Y455 PolarHBondContact O-N 3.47Å
456	S	50	Low	53.9	Low	98 Å²	98	124.3 Å²	124.3	69%	0.685	65%	0.645	S	S	*	*	H	α-helix	trans	-89.7	-8.8	173	83	0	0	0	0	113.3	R452 Q453 R454	R452-S456 PolarHBondContact O-N 3.11Å; Q453-S456 PolarHBondContact O-N 3.46Å; Q453-S456 PolarHBondContact O-OG 3.04Å; R454-S456 VanDerWaalsContact C-N 3.34Å; R454-S456 PolarHBondContact O-N 3.33Å
457	S	48.5	Very low	52.7	Low	93 Å²	93	128.8 Å²	128.8	65%	0.65	66%	0.658	S	S	*	*			trans	-104.7	-0.5	178.4	61.9	0	0	0	0	113.6	Q453 R454	Q453-S457 WeakPolarHBondContact O-CB 3.48Å; Q453-S457 PolarHBondContact O-N 3.45Å; Q453-S457 VanDerWaalsContact O-N 3.15Å; Q453-S457 PolarHBondContact O-OG 2.99Å; R454-S457 WeakPolarHBondContact CA-OG 3.4Å; R454-S457 PolarHBondContact O-N 3.04Å; R454-S457 PolarHBondContact O-OG 3.28Å
458	S	41.3	Very low	51.7	Low	153 Å²	153	123.9 Å²	123.9	100%	1.07	66%	0.655	S	S	*	*			trans	-112.2	0	170.3	-58.2	0	0	0	0	107.9	R454	R454-S458 PolarHBondContact O-N 2.74Å; R454-S458 PolarHBondContact O-OG 3.3Å

Retrieved 458 of 458 residues in 159.1 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).