A0A087YGR9_POEFO Loading...

Eukaryotic translation initiation factor 3 subunit M

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

AlphaFold DB , UniProt , Accession A0A087YGR9, Species POEFO (Poecilia formosa, Amazon molly), Gene EIF3M, Length 376 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	24.9	Very low	36.4	Very low	233 Å²	233	125 Å²	125	100%	1.148	70%	0.696	S	S	*	*				0	124.7	0	-89.5	-156.7	-78.3	0	0	107.3	V3	M1-V3 PolarHBondContact O-N 3.16Å
2	S	38.7	Very low	37.1	Very low	123 Å²	123	126.8 Å²	126.8	86%	0.86	70%	0.695	S	S	*	*			trans	-46.8	120.5	-177.5	46.6	0	0	0	0	113.4
3	V	28.5	Very low	37.8	Very low	127 Å²	127	122.8 Å²	122.8	77%	0.77	67%	0.673	S	S	*	*			trans	-119.4	130.3	165.7	-172.4	0	0	0	0	105.3	M1 A5	M1-V3 PolarHBondContact O-N 3.16Å; V3-A5 PolarHBondContact O-N 3.22Å
4	P	33.6	Very low	38.7	Very low	125 Å²	125	116.6 Å²	116.6	81%	0.812	64%	0.636	S	S	*	*			trans	-68.7	119.2	-145.9	25.2	-33.9	0	0	0	112.9
5	A	32.2	Very low	39.3	Very low	57 Å²	57	109.6 Å²	109.6	47%	0.471	60%	0.601	S	S	.	*			trans	-61.8	139	154.5	0	0	0	0	0	108.2	V3 I7	V3-A5 PolarHBondContact O-N 3.22Å; A5-I7 PolarHBondContact O-N 2.95Å
6	F	37.8	Very low	39.8	Very low	175 Å²	175	106.4 Å²	106.4	77%	0.768	59%	0.589	S	S	*	*	S	Bend	trans	-67.7	-35.5	-176.4	-156.8	-111.3	0	0	0	111.7
7	I	34	Very low	40.4	Very low	80 Å²	80	107 Å²	107	41%	0.41	59%	0.586	S	S	.	*			trans	-157.2	138.2	165.4	-65.9	97.1	0	0	0	109.6	A5 I9 Q14	A5-I7 PolarHBondContact O-N 2.95Å; I7-I9 HydrophobicContact CB-CG1 4.02Å; I7-I9 HydrophobicContact CG2-CD1 3.98Å; I7-I9 HydrophobicContact CG2-CG1 3.28Å; I7-I9 PolarHBondContact O-N 3.41Å; I7-I9 VanDerWaalsContact O-N 3.08Å; I7-Q14 PolarHBondContact O-NE2 3.44Å
8	D	39.2	Very low	41.1	Very low	162 Å²	162	101.8 Å²	101.8	87%	0.866	56%	0.557	S	S	*	*			trans	-66.8	84.3	160.2	-74.3	-52.1	0	0	0	110.5
9	I	41.4	Very low	41.5	Very low	96 Å²	96	98.8 Å²	98.8	49%	0.492	54%	0.537	S	S	.	.			trans	-143	161.1	160.4	9.8	159.7	0	0	0	112.1	I7	I7-I9 HydrophobicContact CB-CG1 4.02Å; I7-I9 HydrophobicContact CG2-CD1 3.98Å; I7-I9 HydrophobicContact CG2-CG1 3.28Å; I7-I9 PolarHBondContact O-N 3.41Å; I7-I9 VanDerWaalsContact O-N 3.08Å
10	T	44.5	Very low	41.7	Very low	95 Å²	95	97.4 Å²	97.4	58%	0.583	54%	0.535	S	S	*	.			trans	-39.7	142.7	-173.6	9.7	0	0	0	0	115.8	E12 D13 Q14	T10-E12 PolarHBondContact O-N 3.42Å; T10-D13 PolarHBondContact O-N 3.08Å; T10-D13 PolarHBondContact OG1-OD2 2.95Å; T10-Q14 PolarHBondContact O-N 3.46Å
11	E	45.7	Very low	42.2	Very low	102 Å²	102	96.2 Å²	96.2	48%	0.477	52%	0.523	S	S	.	.	H	α-helix	trans	-50	-29.9	-174.6	-61.4	167.5	-179.8	0	0	114.5	A15	E11-A15 WeakPolarHBondContact O-CB 3.49Å; E11-A15 PolarHBondContact O-N 3.23Å
12	E	45	Very low	43.4	Very low	146 Å²	146	85.3 Å²	85.3	68%	0.682	47%	0.469	S	S	*	.	H	α-helix	trans	-78.5	-30.2	178.3	-65.5	-177.9	151.7	0	0	113.1	T10 S16	T10-E12 PolarHBondContact O-N 3.42Å; E12-S16 VanDerWaalsContact O-CB 3.32Å; E12-S16 WeakPolarHBondContact O-CB 3.34Å; E12-S16 PolarHBondContact O-N 3.19Å; E12-S16 VanDerWaalsContact O-N 3.09Å; E12-S16 PolarHBondContact O-OG 2.83Å
13	D	46.5	Very low	43.9	Very low	76 Å²	76	85 Å²	85	41%	0.406	45%	0.452	S	S	.	.	H	α-helix	trans	-78.1	-36.6	-179.6	-70.2	-39.3	0	0	0	111.5	T10 S16 E17	T10-D13 PolarHBondContact O-N 3.08Å; T10-D13 PolarHBondContact OG1-OD2 2.95Å; D13-S16 WeakPolarHBondContact CA-OG 3.27Å; D13-S16 PolarHBondContact O-OG 2.67Å; D13-E17 WeakPolarHBondContact O-CB 3.33Å; D13-E17 PolarHBondContact O-N 3.07Å
14	Q	50.4	Low	44.7	Very low	35 Å²	35	83 Å²	83	16%	0.164	45%	0.45	C	S	.	.	H	α-helix	trans	-70	-38.6	173.6	-80.9	-170.9	-15.5	0	0	112.7	I7 T10 S16 L18 L70	I7-Q14 PolarHBondContact O-NE2 3.44Å; T10-Q14 PolarHBondContact O-N 3.46Å; Q14-S16 VanDerWaalsContact C-N 3.35Å; Q14-L18 WeakPolarHBondContact O-CB 3.32Å; Q14-L18 PolarHBondContact O-N 3.37Å; Q14-L70 HydrophobicContact CB-CD1 4.44Å; Q14-L70 HydrophobicContact CB-CD2 4.22Å
15	A	47.3	Very low	45.1	Very low	12 Å²	12	79.8 Å²	79.8	10%	0.099	42%	0.423	C	S	.	.	H	α-helix	trans	-67.1	-37.4	176.3	0	0	0	0	0	111.8	E11 R19	E11-A15 WeakPolarHBondContact O-CB 3.49Å; E11-A15 PolarHBondContact O-N 3.23Å; A15-R19 WeakPolarHBondContact O-CB 3.24Å; A15-R19 PolarHBondContact O-N 3.04Å
16	S	46.7	Very low	45.3	Very low	59 Å²	59	80.1 Å²	80.1	41%	0.413	43%	0.432	S	S	.	.	H	α-helix	trans	-73.7	-35.3	176.7	60.9	0	0	0	0	113.1	E12 D13 Q14 R19 S20	E12-S16 VanDerWaalsContact O-CB 3.32Å; E12-S16 WeakPolarHBondContact O-CB 3.34Å; E12-S16 PolarHBondContact O-N 3.19Å; E12-S16 VanDerWaalsContact O-N 3.09Å; E12-S16 PolarHBondContact O-OG 2.83Å; D13-S16 WeakPolarHBondContact CA-OG 3.27Å; D13-S16 PolarHBondContact O-OG 2.67Å; Q14-S16 VanDerWaalsContact C-N 3.35Å; S16-R19 WeakPolarHBondContact O-CB 3.44Å; S16-R19 PolarHBondContact O-N 3.16Å; S16-S20 PolarHBondContact O-N 2.95Å; S16-S20 PolarHBondContact O-OG 2.88Å
17	E	51.1	Low	45	Very low	116 Å²	116	72.6 Å²	72.6	54%	0.542	40%	0.402	S	S	.	.	H	α-helix	trans	-68.8	-37.4	170.9	-86.1	-166.8	156	0	0	113	D13 R19 S20 Y21	D13-E17 WeakPolarHBondContact O-CB 3.33Å; D13-E17 PolarHBondContact O-N 3.07Å; E17-R19 VanDerWaalsContact C-N 3.32Å; E17-R19 PolarHBondContact O-N 3.48Å; E17-S20 WeakPolarHBondContact CA-OG 3.44Å; E17-S20 PolarHBondContact O-N 3.3Å; E17-S20 PolarHBondContact O-OG 3.43Å; E17-Y21 WeakPolarHBondContact O-CB 3.27Å; E17-Y21 PolarHBondContact O-N 2.9Å
18	L	52.1	Low	44.9	Very low	13 Å²	13	77.3 Å²	77.3	7%	0.068	43%	0.428	C	S	.	.	H	α-helix	trans	-63.6	-39.9	171.3	-108.2	117.5	0	0	0	111.4	Q14 Y21 I22 I45 V63 I67 L70	Q14-L18 WeakPolarHBondContact O-CB 3.32Å; Q14-L18 PolarHBondContact O-N 3.37Å; L18-Y21 PolarHBondContact O-N 3.13Å; L18-I22 HydrophobicContact CD2-CD1 4.38Å; L18-I22 WeakPolarHBondContact O-CB 3.21Å; L18-I22 WeakPolarHBondContact O-CD1 3.41Å; L18-I22 WeakPolarHBondContact O-CG1 3.22Å; L18-I22 PolarHBondContact O-N 3.22Å; L18-I45 HydrophobicContact CD2-CG2 3.82Å; L18-V63 HydrophobicContact CD2-CG1 3.76Å; L18-I67 HydrophobicContact CD2-CD1 3.96Å; L18-I67 HydrophobicContact CD2-CG1 3.83Å; L18-L70 HydrophobicContact CD1-CD1 4.13Å
19	R	48.3	Very low	44.8	Very low	46 Å²	46	71.5 Å²	71.5	17%	0.174	40%	0.396	C	S	.	.	H	α-helix	trans	-63	-43.9	174.6	-108.5	-173.7	171.3	139.8	6.3	112.1	A15 S16 E17 Y21 I22 K23 D41 Q44	A15-R19 WeakPolarHBondContact O-CB 3.24Å; A15-R19 PolarHBondContact O-N 3.04Å; S16-R19 WeakPolarHBondContact O-CB 3.44Å; S16-R19 PolarHBondContact O-N 3.16Å; E17-R19 VanDerWaalsContact C-N 3.32Å; E17-R19 PolarHBondContact O-N 3.48Å; R19-Y21 VanDerWaalsContact C-N 3.32Å; R19-Y21 PolarHBondContact O-N 3.29Å; R19-I22 PolarHBondContact O-N 3.19Å; R19-K23 WeakPolarHBondContact O-CB 3.35Å; R19-K23 PolarHBondContact O-N 2.75Å; R19-D41 IonicContact CZ-OD1 2.91Å; R19-D41 IonicContact CZ-OD2 3.99Å; R19-D41 IonicContact NH1-OD1 3.32Å; R19-D41 PolarHBondContact NH1-OD1 3.01Å; R19-D41 IonicContact NH1-OD2 3.81Å; R19-D41 PolarHBondContact NH1-OD2 3.07Å; R19-D41 IonicContact NH2-OD1 3.64Å; R19-D41 PolarHBondContact NH2-OD1 3.39Å; R19-D41 IonicContact NH2-OD2 3.43Å; R19-Q44 VanDerWaalsContact NH2-OE1 3.16Å
20	S	47.2	Very low	44.4	Very low	70 Å²	70	71.7 Å²	71.7	49%	0.49	41%	0.407	S	S	.	.	H	α-helix	trans	-67.1	-35.5	179.3	68.7	0	0	0	0	111.7	S16 E17 A24	S16-S20 PolarHBondContact O-N 2.95Å; S16-S20 PolarHBondContact O-OG 2.88Å; E17-S20 WeakPolarHBondContact CA-OG 3.44Å; E17-S20 PolarHBondContact O-N 3.3Å; E17-S20 PolarHBondContact O-OG 3.43Å; S20-A24 WeakPolarHBondContact O-CB 3.46Å; S20-A24 PolarHBondContact O-N 3.37Å
21	Y	51	Low	44	Very low	73 Å²	73	75.2 Å²	75.2	29%	0.286	42%	0.416	S	S	.	.	H	α-helix	trans	-69.2	-39.6	173.4	-166.4	-93.7	0	0	0	112.8	E17 L18 R19 A24 K25 D59 V63	E17-Y21 WeakPolarHBondContact O-CB 3.27Å; E17-Y21 PolarHBondContact O-N 2.9Å; L18-Y21 PolarHBondContact O-N 3.13Å; R19-Y21 VanDerWaalsContact C-N 3.32Å; R19-Y21 PolarHBondContact O-N 3.29Å; Y21-A24 WeakPolarHBondContact O-CB 3.46Å; Y21-A24 PolarHBondContact O-N 3.4Å; Y21-K25 HydrophobicContact CE1-CD 3.85Å; Y21-K25 PolarHBondContact O-N 3.4Å; Y21-K25 VanDerWaalsContact O-N 3.11Å; Y21-K25 VanDerWaalsContact OH-CE 3.29Å; Y21-K25 WeakPolarHBondContact OH-CE 3.34Å; Y21-K25 PolarHBondContact OH-NZ 2.81Å; Y21-D59 WeakPolarHBondContact OH-CB 3.45Å; Y21-D59 VanDerWaalsContact OH-CG 3.24Å; Y21-D59 PolarHBondContact OH-OD2 3.19Å; Y21-V63 HydrophobicContact CD1-CG2 4.07Å; Y21-V63 HydrophobicContact CE1-CG2 4.03Å
22	I	50.5	Low	43.4	Very low	4 Å²	4	78.3 Å²	78.3	2%	0.021	43%	0.431	C	S	.	.	H	α-helix	trans	-67.8	-36.8	175.3	-74.1	167.1	0	0	0	111.8	L18 R19 K25 G26 A27 I29 I45 A48	L18-I22 HydrophobicContact CD2-CD1 4.38Å; L18-I22 WeakPolarHBondContact O-CB 3.21Å; L18-I22 WeakPolarHBondContact O-CD1 3.41Å; L18-I22 WeakPolarHBondContact O-CG1 3.22Å; L18-I22 PolarHBondContact O-N 3.22Å; R19-I22 PolarHBondContact O-N 3.19Å; I22-K25 PolarHBondContact O-N 2.98Å; I22-G26 PolarHBondContact O-N 3.22Å; I22-A27 HydrophobicContact CG2-CB 3.78Å; I22-A27 PolarHBondContact O-N 3.01Å; I22-I29 HydrophobicContact CG2-CD1 3.83Å; I22-I45 HydrophobicContact CD1-CG2 4.19Å; I22-A48 HydrophobicContact CD1-CB 4.18Å; I22-A48 HydrophobicContact CG2-CB 3.63Å
23	K	48.5	Very low	43	Very low	115 Å²	115	77.8 Å²	77.8	50%	0.5	43%	0.433	S	S	.	.	H	α-helix	trans	-66.4	-38.1	172.8	-163.5	176.5	-175.5	178.2	0	111.1	R19 K25 G26 E31	R19-K23 WeakPolarHBondContact O-CB 3.35Å; R19-K23 PolarHBondContact O-N 2.75Å; K23-K25 VanDerWaalsContact C-N 3.28Å; K23-K25 PolarHBondContact O-N 3.39Å; K23-G26 PolarHBondContact O-N 3.46Å; K23-E31 IonicContact NZ-OE2 3.77Å; K23-E31 PolarHBondContact NZ-OE2 3.02Å; K23-E31 VanDerWaalsContact NZ-OE2 3.09Å
24	A	46.1	Very low	42.2	Very low	87 Å²	87	76.7 Å²	76.7	72%	0.719	43%	0.434	S	S	*	.	H	α-helix	trans	-66.1	-27.8	174.9	0	0	0	0	0	113.3	S20 Y21	S20-A24 WeakPolarHBondContact O-CB 3.46Å; S20-A24 PolarHBondContact O-N 3.37Å; Y21-A24 WeakPolarHBondContact O-CB 3.46Å; Y21-A24 PolarHBondContact O-N 3.4Å
25	K	42.4	Very low	41.4	Very low	56 Å²	56	85.1 Å²	85.1	24%	0.243	47%	0.474	C	S	.	.	T	Hydrogen-bonded Turn	trans	-94.1	5.5	176.3	-80.2	-169.5	169.9	-178.6	0	115	Y21 I22 K23 D55	Y21-K25 HydrophobicContact CE1-CD 3.85Å; Y21-K25 PolarHBondContact O-N 3.4Å; Y21-K25 VanDerWaalsContact O-N 3.11Å; Y21-K25 VanDerWaalsContact OH-CE 3.29Å; Y21-K25 WeakPolarHBondContact OH-CE 3.34Å; Y21-K25 PolarHBondContact OH-NZ 2.81Å; I22-K25 PolarHBondContact O-N 2.98Å; K23-K25 VanDerWaalsContact C-N 3.28Å; K23-K25 PolarHBondContact O-N 3.39Å; K25-D55 HydrophobicContact CD-CB 4.48Å; K25-D55 PolarHBondContact NZ-O 2.85Å; K25-D55 VanDerWaalsContact NZ-O 3.14Å
26	G	35	Very low	40.9	Very low	64 Å²	64	86.9 Å²	86.9	66%	0.66	49%	0.493	S	S	*	.	T	Hydrogen-bonded Turn	trans	98.1	28	163.2	0	0	0	0	0	117.5	I22 K23	I22-G26 PolarHBondContact O-N 3.22Å; K23-G26 PolarHBondContact O-N 3.46Å
27	A	31.6	Very low	40.7	Very low	18 Å²	18	85.9 Å²	85.9	15%	0.149	49%	0.492	C	S	.	.			trans	-100.3	133.2	167.2	0	0	0	0	0	111.7	I22 I29 A48 V51	I22-A27 HydrophobicContact CG2-CB 3.78Å; I22-A27 PolarHBondContact O-N 3.01Å; A27-I29 PolarHBondContact O-N 3.27Å; A27-A48 HydrophobicContact CB-CB 4.46Å; A27-V51 HydrophobicContact CB-CG2 4.49Å
28	D	32	Very low	40.5	Very low	179 Å²	179	83.3 Å²	83.3	96%	0.957	48%	0.482	S	S	*	.			trans	-71.9	105	172.4	-97	-45.1	0	0	0	110.3
29	I	38.4	Very low	39.9	Very low	39 Å²	39	85.5 Å²	85.5	20%	0.2	49%	0.491	C	S	.	.			trans	-138.8	132.2	164.5	-24.6	173.8	0	0	0	109.4	I22 A27 A48	I22-I29 HydrophobicContact CG2-CD1 3.83Å; A27-I29 PolarHBondContact O-N 3.27Å; I29-A48 HydrophobicContact CD1-CB 3.94Å
30	S	32.9	Very low	40	Very low	101 Å²	101	86.5 Å²	86.5	71%	0.706	50%	0.502	S	S	*	.			trans	-68.3	156.4	-177.4	-80.8	0	0	0	0	114.2	E32	S30-E32 VanDerWaalsContact C-N 3.33Å; S30-E32 PolarHBondContact O-N 3.23Å
31	E	35.6	Very low	40.1	Very low	169 Å²	169	83.9 Å²	83.9	79%	0.79	48%	0.483	S	S	*	.	S	Bend	trans	-84.1	10	-171	-149.7	162.8	146.7	0	0	114.8	K23	K23-E31 IonicContact NZ-OE2 3.77Å; K23-E31 PolarHBondContact NZ-OE2 3.02Å; K23-E31 VanDerWaalsContact NZ-OE2 3.09Å
32	E	32.9	Very low	40.2	Very low	167 Å²	167	81 Å²	81	78%	0.78	47%	0.472	S	S	*	.	S	Bend	trans	-121.8	134.6	-177.2	-71.1	-173.1	161.9	0	0	112.2	S30 A34	S30-E32 VanDerWaalsContact C-N 3.33Å; S30-E32 PolarHBondContact O-N 3.23Å; E32-A34 PolarHBondContact O-N 3.36Å
33	N	36.5	Very low	40.1	Very low	134 Å²	134	82.7 Å²	82.7	72%	0.717	49%	0.487	S	S	*	.			trans	-53.5	122.3	169.6	-65.5	-19.2	0	0	0	109.6	E35	N33-E35 PolarHBondContact O-N 2.93Å
34	A	30.1	Very low	40.2	Very low	54 Å²	54	81.1 Å²	81.1	45%	0.446	48%	0.482	S	S	.	.			trans	-72.7	127.6	160.7	0	0	0	0	0	107.8	E32 G36 G37	E32-A34 PolarHBondContact O-N 3.36Å; A34-G36 PolarHBondContact O-N 3.11Å; A34-G37 PolarHBondContact O-N 2.74Å
35	E	33.8	Very low	40.5	Very low	211 Å²	211	77.4 Å²	77.4	99%	0.986	45%	0.45	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.7	12.9	175.3	-66	-174.7	149.6	0	0	114.3	N33	N33-E35 PolarHBondContact O-N 2.93Å
36	G	35.8	Very low	41	Very low	50 Å²	50	75 Å²	75	52%	0.515	44%	0.439	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.5	7.1	177.9	0	0	0	0	0	115.4	A34	A34-G36 PolarHBondContact O-N 3.11Å
37	G	42.3	Very low	41.7	Very low	37 Å²	37	77.9 Å²	77.9	38%	0.381	44%	0.436	S	S	.	.			trans	82.8	163.2	170.9	0	0	0	0	0	115.7	A34 H39 V40	A34-G37 PolarHBondContact O-N 2.74Å; G37-H39 PolarHBondContact O-N 3.04Å; G37-V40 PolarHBondContact O-N 3.21Å
38	L	46.7	Very low	42.3	Very low	63 Å²	63	77.4 Å²	77.4	33%	0.33	43%	0.432	S	S	.	.	H	α-helix	trans	-40.5	-23.3	177.9	-79	151.2	0	0	0	115.2	L42	L38-L42 WeakPolarHBondContact O-CB 3.42Å; L38-L42 PolarHBondContact O-N 3.27Å
39	H	41.4	Very low	43.1	Very low	58 Å²	58	69.4 Å²	69.4	27%	0.269	39%	0.39	S	S	.	.	H	α-helix	trans	-73	-38.1	-179.7	-59.6	-66.3	0	0	0	114.6	G37 D41 A43 K78	G37-H39 PolarHBondContact O-N 3.04Å; H39-D41 VanDerWaalsContact C-N 3.35Å; H39-A43 WeakPolarHBondContact O-CB 3.44Å; H39-A43 PolarHBondContact O-N 3.42Å; H39-K78 WeakPolarHBondContact CE1-CD 3.16Å; H39-K78 VanDerWaalsContact NE2-CD 3.35Å; H39-K78 WeakPolarHBondContact NE2-CD 3.44Å; H39-K78 PolarHBondContact NE2-NZ 3.3Å; H39-K78 VanDerWaalsContact NE2-NZ 3.18Å
40	V	49.4	Very low	43.4	Very low	67 Å²	67	69.8 Å²	69.8	41%	0.406	39%	0.392	S	S	.	.	H	α-helix	trans	-74.4	-35.9	176.7	-178.8	0	0	0	0	109.6	G37 A43 Q44	G37-V40 PolarHBondContact O-N 3.21Å; V40-A43 PolarHBondContact O-N 3.37Å; V40-Q44 WeakPolarHBondContact O-CG 3.28Å; V40-Q44 PolarHBondContact O-N 2.88Å
41	D	49.2	Very low	43.9	Very low	16 Å²	16	67.7 Å²	67.7	9%	0.086	38%	0.375	C	S	.	.	H	α-helix	trans	-65.8	-43.5	174.2	-80	0.5	0	0	0	111.4	R19 H39 A43 Q44 I45	R19-D41 IonicContact CZ-OD1 2.91Å; R19-D41 IonicContact CZ-OD2 3.99Å; R19-D41 IonicContact NH1-OD1 3.32Å; R19-D41 PolarHBondContact NH1-OD1 3.01Å; R19-D41 IonicContact NH1-OD2 3.81Å; R19-D41 PolarHBondContact NH1-OD2 3.07Å; R19-D41 IonicContact NH2-OD1 3.64Å; R19-D41 PolarHBondContact NH2-OD1 3.39Å; R19-D41 IonicContact NH2-OD2 3.43Å; H39-D41 VanDerWaalsContact C-N 3.35Å; D41-A43 PolarHBondContact O-N 3.49Å; D41-Q44 PolarHBondContact O-N 2.98Å; D41-I45 WeakPolarHBondContact O-CB 3.05Å; D41-I45 WeakPolarHBondContact O-CD1 3.39Å; D41-I45 WeakPolarHBondContact O-CG1 3.23Å; D41-I45 PolarHBondContact O-N 3.35Å
42	L	52.1	Low	44	Very low	11 Å²	11	60 Å²	60	6%	0.058	34%	0.34	C	S	.	.	H	α-helix	trans	-63.4	-39.3	172.4	-113.4	99.7	0	0	0	112.5	L38 I45 I46 L71 L74 L82	L38-L42 WeakPolarHBondContact O-CB 3.42Å; L38-L42 PolarHBondContact O-N 3.27Å; L42-I45 PolarHBondContact O-N 2.91Å; L42-I46 WeakPolarHBondContact O-CB 3.43Å; L42-I46 WeakPolarHBondContact O-CD1 3.41Å; L42-I46 WeakPolarHBondContact O-CG1 3.48Å; L42-I46 PolarHBondContact O-N 2.88Å; L42-L71 HydrophobicContact CD2-CD2 3.62Å; L42-L71 HydrophobicContact CD2-CG 4.23Å; L42-L74 HydrophobicContact CD1-CD1 4Å; L42-L74 HydrophobicContact CD2-CD1 4.33Å; L42-L82 HydrophobicContact CD2-CD1 4.33Å
43	A	49.4	Very low	44.7	Very low	41 Å²	41	54.3 Å²	54.3	34%	0.339	32%	0.315	S	S	.	.	H	α-helix	trans	-65.1	-39.6	177.5	0	0	0	0	0	111.9	H39 V40 D41 I46 E47 L82	H39-A43 WeakPolarHBondContact O-CB 3.44Å; H39-A43 PolarHBondContact O-N 3.42Å; V40-A43 PolarHBondContact O-N 3.37Å; D41-A43 PolarHBondContact O-N 3.49Å; A43-I46 PolarHBondContact O-N 3.24Å; A43-E47 WeakPolarHBondContact O-CG 3.03Å; A43-E47 PolarHBondContact O-N 2.81Å; A43-L82 HydrophobicContact CB-CD2 4.2Å
44	Q	50.4	Low	45.2	Very low	81 Å²	81	55.9 Å²	55.9	38%	0.379	32%	0.315	S	S	.	.	H	α-helix	trans	-68.9	-37.1	172.9	-77.9	-176.8	-9.8	0	0	112.5	R19 V40 D41 I46 E47 A48	R19-Q44 VanDerWaalsContact NH2-OE1 3.16Å; V40-Q44 WeakPolarHBondContact O-CG 3.28Å; V40-Q44 PolarHBondContact O-N 2.88Å; D41-Q44 PolarHBondContact O-N 2.98Å; Q44-I46 VanDerWaalsContact C-N 3.34Å; Q44-E47 PolarHBondContact O-N 3.35Å; Q44-A48 VanDerWaalsContact O-CB 3.31Å; Q44-A48 WeakPolarHBondContact O-CB 3.22Å; Q44-A48 PolarHBondContact O-N 2.82Å
45	I	52.4	Low	45.7	Very low	9 Å²	9	57.8 Å²	57.8	5%	0.046	32%	0.318	C	S	.	.	H	α-helix	trans	-64.1	-41.4	173.6	-70.8	163.7	0	0	0	110.1	L18 I22 D41 L42 A48 C49 I67	L18-I45 HydrophobicContact CD2-CG2 3.82Å; I22-I45 HydrophobicContact CD1-CG2 4.19Å; D41-I45 WeakPolarHBondContact O-CB 3.05Å; D41-I45 WeakPolarHBondContact O-CD1 3.39Å; D41-I45 WeakPolarHBondContact O-CG1 3.23Å; D41-I45 PolarHBondContact O-N 3.35Å; L42-I45 PolarHBondContact O-N 2.91Å; I45-A48 CarbonylContact O-C 3.57Å; I45-A48 PolarHBondContact O-N 2.78Å; I45-C49 PolarHBondContact O-N 2.83Å; I45-C49 PolarHBondContact O-SG 2.92Å; I45-I67 HydrophobicContact CG2-CD1 4.39Å; I45-I67 HydrophobicContact CG2-CG1 4.48Å
46	I	53.2	Low	46	Very low	5 Å²	5	53.6 Å²	53.6	3%	0.026	30%	0.302	C	S	.	.	H	α-helix	trans	-66.2	-36.5	174.6	-68.7	164.2	0	0	0	111.5	L42 A43 Q44 L82 L86 K89	L42-I46 WeakPolarHBondContact O-CB 3.43Å; L42-I46 WeakPolarHBondContact O-CD1 3.41Å; L42-I46 WeakPolarHBondContact O-CG1 3.48Å; L42-I46 PolarHBondContact O-N 2.88Å; A43-I46 PolarHBondContact O-N 3.24Å; Q44-I46 VanDerWaalsContact C-N 3.34Å; I46-L82 HydrophobicContact CD1-CB 4.3Å; I46-L82 HydrophobicContact CD1-CD2 3.95Å; I46-L86 HydrophobicContact CG2-CD1 4.07Å; I46-K89 HydrophobicContact CG2-CD 4.46Å
47	E	50.3	Low	46.6	Very low	125 Å²	125	55 Å²	55	58%	0.584	30%	0.298	S	S	*	.	H	α-helix	trans	-64.9	-40.7	170.7	-75.7	-105.8	122.4	0	0	112.5	A43 Q44 K89	A43-E47 WeakPolarHBondContact O-CG 3.03Å; A43-E47 PolarHBondContact O-N 2.81Å; Q44-E47 PolarHBondContact O-N 3.35Å; E47-K89 IonicContact OE1-NZ 2.87Å; E47-K89 PolarHBondContact OE1-NZ 3.24Å
48	A	44.3	Very low	46.9	Very low	9 Å²	9	61.5 Å²	61.5	7%	0.074	32%	0.316	C	S	.	.	H	α-helix	trans	-80.7	-13.9	-179.2	0	0	0	0	0	113.8	I22 A27 I29 Q44 I45 D50 V51 C52	I22-A48 HydrophobicContact CD1-CB 4.18Å; I22-A48 HydrophobicContact CG2-CB 3.63Å; A27-A48 HydrophobicContact CB-CB 4.46Å; I29-A48 HydrophobicContact CD1-CB 3.94Å; Q44-A48 VanDerWaalsContact O-CB 3.31Å; Q44-A48 WeakPolarHBondContact O-CB 3.22Å; Q44-A48 PolarHBondContact O-N 2.82Å; I45-A48 CarbonylContact O-C 3.57Å; I45-A48 PolarHBondContact O-N 2.78Å; A48-D50 PolarHBondContact O-N 2.81Å; A48-V51 PolarHBondContact O-N 3.48Å; A48-V51 VanDerWaalsContact O-N 3.07Å; A48-C52 PolarHBondContact O-N 3.22Å
49	C	47.9	Very low	47.1	Very low	10 Å²	10	61.8 Å²	61.8	7%	0.068	32%	0.318	C	S	.	.	H	α-helix	trans	-59.9	-26.2	171	-79	0	0	0	0	112.8	I45 V51 C52 L53 I67	I45-C49 PolarHBondContact O-N 2.83Å; I45-C49 PolarHBondContact O-SG 2.92Å; C49-V51 PolarHBondContact O-N 3.24Å; C49-C52 PolarHBondContact O-N 3.42Å; C49-L53 WeakPolarHBondContact O-CD1 3.44Å; C49-L53 PolarHBondContact O-N 3.39Å; C49-I67 WeakPolarHBondContact SG-CD1 3.37Å
50	D	44.8	Very low	47.6	Very low	47 Å²	47	59.2 Å²	59.2	25%	0.251	31%	0.306	S	S	.	.	H	α-helix	trans	-61.2	-26.6	175	-74.3	-11.2	0	0	0	112.6	A48 K89 F93	A48-D50 PolarHBondContact O-N 2.81Å; D50-K89 IonicContact OD2-NZ 3.08Å; D50-F93 HydrophobicContact CB-CE2 4.49Å; D50-F93 HydrophobicContact CB-CZ 3.99Å; D50-F93 WeakPolarHBondContact OD1-CE2 3.42Å; D50-F93 WeakPolarHBondContact OD1-CZ 3.4Å
51	V	43.8	Very low	47.8	Very low	58 Å²	58	59.4 Å²	59.4	35%	0.352	30%	0.302	S	S	.	.	H	α-helix	trans	-86.9	-38.5	176.5	-177.8	0	0	0	0	110.9	A27 A48 C49 L53 K54	A27-V51 HydrophobicContact CB-CG2 4.49Å; A48-V51 PolarHBondContact O-N 3.48Å; A48-V51 VanDerWaalsContact O-N 3.07Å; C49-V51 PolarHBondContact O-N 3.24Å; V51-L53 VanDerWaalsContact C-N 3.3Å; V51-L53 PolarHBondContact O-N 3.41Å; V51-K54 PolarHBondContact O-N 2.87Å
52	C	37.3	Very low	47.9	Very low	7 Å²	7	61.2 Å²	61.2	5%	0.047	32%	0.316	C	S	.	.	H	α-helix	trans	-69.5	-27.5	-178.1	-139.7	0	0	0	0	113	A48 C49 K54 V60	A48-C52 PolarHBondContact O-N 3.22Å; C49-C52 PolarHBondContact O-N 3.42Å; C52-K54 PolarHBondContact O-N 3.3Å; C52-V60 WeakPolarHBondContact O-CG2 3.26Å
53	L	48.6	Very low	48	Very low	47 Å²	47	61.5 Å²	61.5	25%	0.246	32%	0.318	C	S	.	.	T	Hydrogen-bonded Turn	trans	-67.4	-8.2	174.7	-88.6	155.6	0	0	0	114.9	C49 V51 V60 M64	C49-L53 WeakPolarHBondContact O-CD1 3.44Å; C49-L53 PolarHBondContact O-N 3.39Å; V51-L53 VanDerWaalsContact C-N 3.3Å; V51-L53 PolarHBondContact O-N 3.41Å; L53-V60 HydrophobicContact CD2-CG1 3.75Å; L53-V60 HydrophobicContact CG-CG1 4.31Å; L53-M64 HydrophobicContact CD1-CE 3.6Å; L53-M64 HydrophobicContact CD2-CE 3.56Å; L53-M64 HydrophobicContact CD2-SD 4.32Å; L53-M64 HydrophobicContact CG-CE 3.68Å
54	K	46.1	Very low	48.2	Very low	167 Å²	167	60.6 Å²	60.6	73%	0.726	31%	0.307	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.2	-15.4	178.5	-71.6	-176.8	177.2	176.7	0	114.5	V51 C52	V51-K54 PolarHBondContact O-N 2.87Å; C52-K54 PolarHBondContact O-N 3.3Å
55	D	39.6	Very low	48.4	Very low	95 Å²	95	59.3 Å²	59.3	51%	0.508	30%	0.303	S	S	.	.	S	Bend	trans	-131.5	138.6	-176.8	-95	-56.7	0	0	0	114.3	K25 V60	K25-D55 HydrophobicContact CD-CB 4.48Å; K25-D55 PolarHBondContact NZ-O 2.85Å; K25-D55 VanDerWaalsContact NZ-O 3.14Å; D55-V60 WeakPolarHBondContact O-CG2 3.4Å
56	D	40.3	Very low	48.5	Very low	122 Å²	122	60.1 Å²	60.1	65%	0.652	31%	0.31	S	S	*	.			trans	35.1	118.9	175.5	-86.9	-51.7	0	0	0	120.5	K58 D59 V60	D56-K58 PolarHBondContact O-N 3.46Å; D56-D59 PolarHBondContact O-N 3.39Å; D56-V60 WeakPolarHBondContact O-CG2 3.31Å; D56-V60 PolarHBondContact O-N 3.19Å
57	D	48.4	Very low	48.6	Very low	80 Å²	80	60.5 Å²	60.5	43%	0.428	31%	0.312	S	S	.	.	H	α-helix	trans	-54.8	-36	-172.5	-81	-24.1	0	0	0	115.9	E61 R98	D57-E61 WeakPolarHBondContact O-CG 3.39Å; D57-E61 PolarHBondContact O-N 3.34Å; D57-R98 WeakPolarHBondContact OD1-CD 3.48Å; D57-R98 IonicContact OD1-CZ 2.91Å; D57-R98 IonicContact OD1-NE 2.65Å; D57-R98 IonicContact OD1-NH1 3.4Å; D57-R98 PolarHBondContact OD1-NH1 3.34Å
58	K	49.9	Very low	48.8	Very low	173 Å²	173	55.3 Å²	55.3	75%	0.752	29%	0.288	S	S	*	.	H	α-helix	trans	-79.6	-30.9	-174.6	-70.4	-178.6	179.9	175.7	0	113.4	D56 S62	D56-K58 PolarHBondContact O-N 3.46Å; K58-S62 PolarHBondContact O-N 2.91Å; K58-S62 PolarHBondContact O-OG 3.4Å
59	D	51	Low	49.3	Very low	70 Å²	70	57.2 Å²	57.2	37%	0.374	30%	0.301	S	S	.	.	H	α-helix	trans	-81.1	-31.1	178.4	-73.2	-11.5	0	0	0	110.7	Y21 D56 S62 V63	Y21-D59 WeakPolarHBondContact OH-CB 3.45Å; Y21-D59 VanDerWaalsContact OH-CG 3.24Å; Y21-D59 PolarHBondContact OH-OD2 3.19Å; D56-D59 PolarHBondContact O-N 3.39Å; D59-S62 WeakPolarHBondContact CA-OG 3.21Å; D59-S62 PolarHBondContact O-N 3.49Å; D59-S62 PolarHBondContact O-OG 3.21Å; D59-V63 WeakPolarHBondContact O-CB 3.4Å; D59-V63 WeakPolarHBondContact O-CG2 3.32Å; D59-V63 PolarHBondContact O-N 3.46Å
60	V	51.8	Low	49.5	Very low	3 Å²	3	57.5 Å²	57.5	2%	0.018	30%	0.302	C	S	.	.	H	α-helix	trans	-67.6	-40.1	172.3	178.7	0	0	0	0	111	C52 L53 D55 D56 M64 L101	C52-V60 WeakPolarHBondContact O-CG2 3.26Å; L53-V60 HydrophobicContact CD2-CG1 3.75Å; L53-V60 HydrophobicContact CG-CG1 4.31Å; D55-V60 WeakPolarHBondContact O-CG2 3.4Å; D56-V60 WeakPolarHBondContact O-CG2 3.31Å; D56-V60 PolarHBondContact O-N 3.19Å; V60-M64 HydrophobicContact CG1-CE 4.29Å; V60-M64 HydrophobicContact CG1-CG 4.18Å; V60-M64 HydrophobicContact CG1-SD 3.63Å; V60-M64 WeakPolarHBondContact O-CB 3.46Å; V60-M64 WeakPolarHBondContact O-CG 3.46Å; V60-M64 PolarHBondContact O-N 2.84Å; V60-L101 HydrophobicContact CG1-CD2 4.04Å
61	E	51.9	Low	49.9	Very low	72 Å²	72	55.3 Å²	55.3	34%	0.336	29%	0.29	S	S	.	.	H	α-helix	trans	-62.6	-42.7	174.2	-75.5	-176.4	176.5	0	0	112.6	D57 N65 L101	D57-E61 WeakPolarHBondContact O-CG 3.39Å; D57-E61 PolarHBondContact O-N 3.34Å; E61-N65 VanDerWaalsContact O-CB 3.23Å; E61-N65 WeakPolarHBondContact O-CB 3.46Å; E61-N65 PolarHBondContact O-N 2.95Å; E61-N65 PolarHBondContact O-ND2 3.34Å; E61-N65 VanDerWaalsContact O-ND2 3.13Å; E61-L101 HydrophobicContact CG-CD1 3.38Å; E61-L101 HydrophobicContact CG-CG 4.3Å; E61-L101 WeakPolarHBondContact OE1-CD1 3.25Å
62	S	52.3	Low	50.3	Low	54 Å²	54	56.9 Å²	56.9	38%	0.378	30%	0.296	S	S	.	.	H	α-helix	trans	-70.2	-44.4	180	63.2	0	0	0	0	111.4	K58 D59 M64 N65 S66	K58-S62 PolarHBondContact O-N 2.91Å; K58-S62 PolarHBondContact O-OG 3.4Å; D59-S62 WeakPolarHBondContact CA-OG 3.21Å; D59-S62 PolarHBondContact O-N 3.49Å; D59-S62 PolarHBondContact O-OG 3.21Å; S62-M64 PolarHBondContact O-N 2.98Å; S62-N65 PolarHBondContact O-N 2.8Å; S62-S66 WeakPolarHBondContact O-CB 3.09Å; S62-S66 PolarHBondContact O-N 2.73Å; S62-S66 PolarHBondContact O-OG 2.88Å
63	V	54.3	Low	50.9	Low	16 Å²	16	61.5 Å²	61.5	10%	0.097	32%	0.319	C	S	.	.	H	α-helix	trans	-62	-43.2	175.5	170.5	0	0	0	0	110.9	L18 Y21 D59 S66 I67	L18-V63 HydrophobicContact CD2-CG1 3.76Å; Y21-V63 HydrophobicContact CD1-CG2 4.07Å; Y21-V63 HydrophobicContact CE1-CG2 4.03Å; D59-V63 WeakPolarHBondContact O-CB 3.4Å; D59-V63 WeakPolarHBondContact O-CG2 3.32Å; D59-V63 PolarHBondContact O-N 3.46Å; V63-S66 PolarHBondContact O-N 3.12Å; V63-I67 HydrophobicContact CG1-CD1 3.99Å; V63-I67 WeakPolarHBondContact O-CD1 3.39Å; V63-I67 VanDerWaalsContact O-CG1 3.27Å; V63-I67 WeakPolarHBondContact O-CG1 3.19Å; V63-I67 PolarHBondContact O-N 3.3Å
64	M	53.4	Low	50.8	Low	22 Å²	22	61 Å²	61	11%	0.108	32%	0.316	C	S	.	.	H	α-helix	trans	-72.2	-35.9	177.9	-71.1	-178.4	149.4	0	0	112.5	L53 V60 S62 S66 I67 V68 L101 L105	L53-M64 HydrophobicContact CD1-CE 3.6Å; L53-M64 HydrophobicContact CD2-CE 3.56Å; L53-M64 HydrophobicContact CD2-SD 4.32Å; L53-M64 HydrophobicContact CG-CE 3.68Å; V60-M64 HydrophobicContact CG1-CE 4.29Å; V60-M64 HydrophobicContact CG1-CG 4.18Å; V60-M64 HydrophobicContact CG1-SD 3.63Å; V60-M64 WeakPolarHBondContact O-CB 3.46Å; V60-M64 WeakPolarHBondContact O-CG 3.46Å; V60-M64 PolarHBondContact O-N 2.84Å; S62-M64 PolarHBondContact O-N 2.98Å; M64-S66 VanDerWaalsContact C-N 3.32Å; M64-S66 PolarHBondContact O-N 3.5Å; M64-I67 PolarHBondContact O-N 3.4Å; M64-V68 WeakPolarHBondContact O-CB 3.33Å; M64-V68 WeakPolarHBondContact O-CG2 3.22Å; M64-V68 PolarHBondContact O-N 3.48Å; M64-L101 HydrophobicContact SD-CD2 4.42Å; M64-L105 HydrophobicContact CB-CD1 4Å; M64-L105 HydrophobicContact CB-CD2 3.46Å; M64-L105 VanDerWaalsContact CB-CD2 3.46Å; M64-L105 HydrophobicContact CB-CG 4.36Å; M64-L105 HydrophobicContact CE-CD1 4.41Å; M64-L105 HydrophobicContact CG-CD1 4.21Å; M64-L105 HydrophobicContact SD-CD1 3.14Å; M64-L105 WeakPolarHBondContact SD-CD1 3.35Å; M64-L105 HydrophobicContact SD-CD2 4.44Å; M64-L105 HydrophobicContact SD-CG 4.38Å
65	N	55.6	Low	50.6	Low	55 Å²	55	59.7 Å²	59.7	29%	0.294	31%	0.313	S	S	.	.	H	α-helix	trans	-64.3	-37.6	171.3	-76.6	-29.6	0	0	0	111.5	E61 S62 V68 S69 N108	E61-N65 VanDerWaalsContact O-CB 3.23Å; E61-N65 WeakPolarHBondContact O-CB 3.46Å; E61-N65 PolarHBondContact O-N 2.95Å; E61-N65 PolarHBondContact O-ND2 3.34Å; E61-N65 VanDerWaalsContact O-ND2 3.13Å; S62-N65 PolarHBondContact O-N 2.8Å; N65-V68 PolarHBondContact O-N 2.81Å; N65-S69 WeakPolarHBondContact O-CB 3.1Å; N65-S69 PolarHBondContact O-N 3.22Å; N65-S69 PolarHBondContact O-OG 3.04Å; N65-S69 VanDerWaalsContact O-OG 3.13Å; N65-N108 PolarHBondContact OD1-ND2 3.25Å
66	S	54	Low	50.9	Low	26 Å²	26	58.7 Å²	58.7	18%	0.182	31%	0.312	C	S	.	.	H	α-helix	trans	-64.7	-41	172.5	-62.6	0	0	0	0	111.9	S62 V63 M64 V68 S69 L70	S62-S66 WeakPolarHBondContact O-CB 3.09Å; S62-S66 PolarHBondContact O-N 2.73Å; S62-S66 PolarHBondContact O-OG 2.88Å; V63-S66 PolarHBondContact O-N 3.12Å; M64-S66 VanDerWaalsContact C-N 3.32Å; M64-S66 PolarHBondContact O-N 3.5Å; S66-V68 VanDerWaalsContact C-N 3.34Å; S66-V68 PolarHBondContact O-N 3.35Å; S66-S69 PolarHBondContact O-N 3.42Å; S66-L70 WeakPolarHBondContact O-CB 3.43Å; S66-L70 VanDerWaalsContact O-CG 3.25Å; S66-L70 WeakPolarHBondContact O-CG 3.37Å; S66-L70 PolarHBondContact O-N 3.28Å
67	I	54.6	Low	50.8	Low	13 Å²	13	61.2 Å²	61.2	7%	0.067	32%	0.319	C	S	.	.	H	α-helix	trans	-64.3	-39.8	173.4	-68.3	161.6	0	0	0	111	L18 I45 C49 V63 M64 L70 L71	L18-I67 HydrophobicContact CD2-CD1 3.96Å; L18-I67 HydrophobicContact CD2-CG1 3.83Å; I45-I67 HydrophobicContact CG2-CD1 4.39Å; I45-I67 HydrophobicContact CG2-CG1 4.48Å; C49-I67 WeakPolarHBondContact SG-CD1 3.37Å; V63-I67 HydrophobicContact CG1-CD1 3.99Å; V63-I67 WeakPolarHBondContact O-CD1 3.39Å; V63-I67 VanDerWaalsContact O-CG1 3.27Å; V63-I67 WeakPolarHBondContact O-CG1 3.19Å; V63-I67 PolarHBondContact O-N 3.3Å; M64-I67 PolarHBondContact O-N 3.4Å; I67-L70 PolarHBondContact O-N 3.19Å; I67-L71 HydrophobicContact CG2-CD1 3.8Å; I67-L71 HydrophobicContact CG2-CG 4.27Å; I67-L71 VanDerWaalsContact O-CB 3.28Å; I67-L71 WeakPolarHBondContact O-CB 3.48Å; I67-L71 WeakPolarHBondContact O-CG 3.26Å; I67-L71 PolarHBondContact O-N 3.43Å
68	V	54.8	Low	50.8	Low	16 Å²	16	62.3 Å²	62.3	10%	0.097	32%	0.32	C	S	.	.	H	α-helix	trans	-64.3	-42.2	175.4	169.8	0	0	0	0	110.7	M64 N65 S66 L71 L72 L109	M64-V68 WeakPolarHBondContact O-CB 3.33Å; M64-V68 WeakPolarHBondContact O-CG2 3.22Å; M64-V68 PolarHBondContact O-N 3.48Å; N65-V68 PolarHBondContact O-N 2.81Å; S66-V68 VanDerWaalsContact C-N 3.34Å; S66-V68 PolarHBondContact O-N 3.35Å; V68-L71 PolarHBondContact O-N 2.77Å; V68-L72 WeakPolarHBondContact O-CB 3.15Å; V68-L72 PolarHBondContact O-N 2.65Å; V68-L109 HydrophobicContact CB-CD2 4.25Å; V68-L109 HydrophobicContact CG1-CD2 3.92Å; V68-L109 HydrophobicContact CG1-CG 4.23Å; V68-L109 HydrophobicContact CG2-CD1 4.3Å; V68-L109 HydrophobicContact CG2-CD2 3.78Å; V68-L109 HydrophobicContact CG2-CG 3.77Å
69	S	54.7	Low	50.8	Low	48 Å²	48	55.1 Å²	55.1	34%	0.336	29%	0.289	S	S	.	.	H	α-helix	trans	-64.2	-43.2	174.6	-68.9	0	0	0	0	112	N65 S66 L72 I73	N65-S69 WeakPolarHBondContact O-CB 3.1Å; N65-S69 PolarHBondContact O-N 3.22Å; N65-S69 PolarHBondContact O-OG 3.04Å; N65-S69 VanDerWaalsContact O-OG 3.13Å; S66-S69 PolarHBondContact O-N 3.42Å; S69-L72 VanDerWaalsContact O-CB 3.3Å; S69-L72 WeakPolarHBondContact O-CB 3.04Å; S69-L72 PolarHBondContact O-N 2.84Å; S69-I73 VanDerWaalsContact O-CD1 3.31Å; S69-I73 WeakPolarHBondContact O-CD1 3.15Å; S69-I73 VanDerWaalsContact O-CG1 3.28Å; S69-I73 WeakPolarHBondContact O-CG1 3.38Å; S69-I73 PolarHBondContact O-N 3.12Å
70	L	52.5	Low	50.7	Low	16 Å²	16	55.4 Å²	55.4	8%	0.084	29%	0.288	C	S	.	.	H	α-helix	trans	-64.2	-42.2	175.1	-71.9	168.3	0	0	0	111.2	Q14 L18 S66 I67 L72 I73 L74	Q14-L70 HydrophobicContact CB-CD1 4.44Å; Q14-L70 HydrophobicContact CB-CD2 4.22Å; L18-L70 HydrophobicContact CD1-CD1 4.13Å; S66-L70 WeakPolarHBondContact O-CB 3.43Å; S66-L70 VanDerWaalsContact O-CG 3.25Å; S66-L70 WeakPolarHBondContact O-CG 3.37Å; S66-L70 PolarHBondContact O-N 3.28Å; I67-L70 PolarHBondContact O-N 3.19Å; L70-L72 PolarHBondContact O-N 3.4Å; L70-I73 PolarHBondContact O-N 3.49Å; L70-L74 WeakPolarHBondContact O-CD1 3.34Å; L70-L74 PolarHBondContact O-N 2.86Å
71	L	52.1	Low	50.8	Low	1 Å²	1	58.4 Å²	58.4	1%	0.005	31%	0.314	C	S	.	.	H	α-helix	trans	-66.5	-22.5	175.1	-75.1	170.5	0	0	0	113.5	L42 I67 V68 I73 Q79 L86 L109	L42-L71 HydrophobicContact CD2-CD2 3.62Å; L42-L71 HydrophobicContact CD2-CG 4.23Å; I67-L71 HydrophobicContact CG2-CD1 3.8Å; I67-L71 HydrophobicContact CG2-CG 4.27Å; I67-L71 VanDerWaalsContact O-CB 3.28Å; I67-L71 WeakPolarHBondContact O-CB 3.48Å; I67-L71 WeakPolarHBondContact O-CG 3.26Å; I67-L71 PolarHBondContact O-N 3.43Å; V68-L71 PolarHBondContact O-N 2.77Å; L71-I73 VanDerWaalsContact C-N 3.35Å; L71-Q79 PolarHBondContact O-NE2 3.49Å; L71-L86 HydrophobicContact CD1-CD2 4.18Å; L71-L109 HydrophobicContact CD1-CD2 4.42Å
72	L	53.7	Low	50.8	Low	91 Å²	91	56 Å²	56	48%	0.476	30%	0.303	S	S	.	.	H	α-helix	trans	-76.3	-24.9	176.6	-140.1	104.3	0	0	0	112.7	V68 S69 L70 G112	V68-L72 WeakPolarHBondContact O-CB 3.15Å; V68-L72 PolarHBondContact O-N 2.65Å; S69-L72 VanDerWaalsContact O-CB 3.3Å; S69-L72 WeakPolarHBondContact O-CB 3.04Å; S69-L72 PolarHBondContact O-N 2.84Å; L70-L72 PolarHBondContact O-N 3.4Å; L72-G112 VanDerWaalsContact CD1-CA 3.44Å; L72-G112 WeakPolarHBondContact CD1-O 3.16Å; L72-G112 WeakPolarHBondContact CG-O 3.44Å
73	I	48.5	Very low	51	Low	104 Å²	104	53.6 Å²	53.6	53%	0.533	29%	0.286	S	S	.	.	H	α-helix	trans	-94.8	-19.1	-173.8	-60.4	161.4	0	0	0	111	S69 L70 L71	S69-I73 VanDerWaalsContact O-CD1 3.31Å; S69-I73 WeakPolarHBondContact O-CD1 3.15Å; S69-I73 VanDerWaalsContact O-CG1 3.28Å; S69-I73 WeakPolarHBondContact O-CG1 3.38Å; S69-I73 PolarHBondContact O-N 3.12Å; L70-I73 PolarHBondContact O-N 3.49Å; L71-I73 VanDerWaalsContact C-N 3.35Å
74	L	46.9	Very low	51.1	Low	36 Å²	36	57.6 Å²	57.6	19%	0.188	30%	0.304	C	S	.	.	S	Bend	trans	-75.4	149	177.5	-92.9	99.3	0	0	0	114	L42 L70	L42-L74 HydrophobicContact CD1-CD1 4Å; L42-L74 HydrophobicContact CD2-CD1 4.33Å; L70-L74 WeakPolarHBondContact O-CD1 3.34Å; L70-L74 PolarHBondContact O-N 2.86Å
75	E	41.3	Very low	51.2	Low	140 Å²	140	59 Å²	59	65%	0.654	32%	0.316	S	S	*	.			trans	-57.1	144.1	179.9	-77.3	179.2	150	0	0	114.7	E77 K78 Q79	E75-E77 PolarHBondContact O-N 2.83Å; E75-K78 PolarHBondContact O-N 3.42Å; E75-Q79 PolarHBondContact O-N 2.97Å
76	P	46.3	Very low	51.2	Low	74 Å²	74	57.7 Å²	57.7	48%	0.481	31%	0.309	S	S	.	.	H	α-helix	trans	-65.6	-26.3	-166.3	23.1	-33.7	0	0	0	115.8
77	E	38	Very low	51.2	Low	175 Å²	175	56.7 Å²	56.7	82%	0.818	30%	0.301	S	S	*	.	H	α-helix	trans	-79.3	-25.6	-175.1	-72.1	-171.1	150.8	0	0	114.2	E75	E75-E77 PolarHBondContact O-N 2.83Å
78	K	48.5	Very low	51.2	Low	103 Å²	103	61.7 Å²	61.7	45%	0.448	33%	0.325	S	S	.	.	H	α-helix	trans	-103.4	-11.9	-179.6	-66.5	172.4	-176.4	163.6	0	112.8	H39 E75 E80	H39-K78 WeakPolarHBondContact CE1-CD 3.16Å; H39-K78 VanDerWaalsContact NE2-CD 3.35Å; H39-K78 WeakPolarHBondContact NE2-CD 3.44Å; H39-K78 PolarHBondContact NE2-NZ 3.3Å; H39-K78 VanDerWaalsContact NE2-NZ 3.18Å; E75-K78 PolarHBondContact O-N 3.42Å; K78-E80 PolarHBondContact O-N 3.43Å
79	Q	49.7	Very low	51.2	Low	22 Å²	22	62.5 Å²	62.5	10%	0.103	33%	0.327	C	S	.	.	H	α-helix	trans	-59	-36.1	169.3	-142.7	-171.2	-5.4	0	0	110.8	L71 E75 L82 I83	L71-Q79 PolarHBondContact O-NE2 3.49Å; E75-Q79 PolarHBondContact O-N 2.97Å; Q79-L82 PolarHBondContact O-N 2.83Å; Q79-I83 HydrophobicContact CB-CD1 4.33Å; Q79-I83 HydrophobicContact CG-CD1 3.65Å; Q79-I83 HydrophobicContact CG-CG1 4.44Å; Q79-I83 WeakPolarHBondContact O-CB 3.15Å; Q79-I83 WeakPolarHBondContact O-CD1 3.24Å; Q79-I83 WeakPolarHBondContact O-CG1 3.32Å; Q79-I83 PolarHBondContact O-N 3.28Å
80	E	49.8	Very low	51.1	Low	76 Å²	76	61.7 Å²	61.7	36%	0.355	32%	0.318	S	S	.	.	H	α-helix	trans	-62.6	-47.8	-173.9	-36.3	-152.9	128	0	0	113	K78 I83 E84 V119	K78-E80 PolarHBondContact O-N 3.43Å; E80-I83 PolarHBondContact O-N 3.26Å; E80-E84 WeakPolarHBondContact O-CB 3.19Å; E80-E84 PolarHBondContact O-N 2.85Å; E80-V119 HydrophobicContact CB-CG2 3.9Å; E80-V119 HydrophobicContact CG-CG2 3.37Å; E80-V119 WeakPolarHBondContact OE1-CG2 3.42Å
81	A	53.6	Low	51.1	Low	67 Å²	67	63.7 Å²	63.7	55%	0.554	33%	0.331	S	S	*	.	H	α-helix	trans	-71.9	-36.5	-177.5	0	0	0	0	0	112.6	S85	A81-S85 WeakPolarHBondContact O-CB 3.45Å; A81-S85 PolarHBondContact O-N 3.34Å
82	L	52.3	Low	51	Low	20 Å²	20	71.5 Å²	71.5	11%	0.105	37%	0.365	C	S	.	.	H	α-helix	trans	-70.1	-38.4	176.2	-70.4	167.8	0	0	0	111.1	L42 A43 I46 Q79 L86	L42-L82 HydrophobicContact CD2-CD1 4.33Å; A43-L82 HydrophobicContact CB-CD2 4.2Å; I46-L82 HydrophobicContact CD1-CB 4.3Å; I46-L82 HydrophobicContact CD1-CD2 3.95Å; Q79-L82 PolarHBondContact O-N 2.83Å; L82-L86 VanDerWaalsContact O-CB 3.28Å; L82-L86 WeakPolarHBondContact O-CB 3.37Å; L82-L86 PolarHBondContact O-N 3.08Å
83	I	56.1	Low	50.4	Low	4 Å²	4	70.9 Å²	70.9	2%	0.021	36%	0.359	C	S	.	.	H	α-helix	trans	-68.9	-40.1	174.5	-74.3	171.6	0	0	0	111.2	Q79 E80 L86 C87 M113 V119 V123	Q79-I83 HydrophobicContact CB-CD1 4.33Å; Q79-I83 HydrophobicContact CG-CD1 3.65Å; Q79-I83 HydrophobicContact CG-CG1 4.44Å; Q79-I83 WeakPolarHBondContact O-CB 3.15Å; Q79-I83 WeakPolarHBondContact O-CD1 3.24Å; Q79-I83 WeakPolarHBondContact O-CG1 3.32Å; Q79-I83 PolarHBondContact O-N 3.28Å; E80-I83 PolarHBondContact O-N 3.26Å; I83-L86 PolarHBondContact O-N 3.28Å; I83-C87 WeakPolarHBondContact O-CB 3.29Å; I83-C87 PolarHBondContact O-N 3.06Å; I83-C87 PolarHBondContact O-SG 3.17Å; I83-M113 HydrophobicContact CD1-SD 3.97Å; I83-V119 HydrophobicContact CB-CG1 4.37Å; I83-V119 HydrophobicContact CD1-CG1 3.4Å; I83-V119 HydrophobicContact CG1-CG1 4.47Å; I83-V119 HydrophobicContact CG2-CG1 4.1Å; I83-V123 HydrophobicContact CG2-CG2 3.28Å
84	E	56.6	Low	50.1	Low	101 Å²	101	75.9 Å²	75.9	47%	0.472	37%	0.371	S	S	.	.	H	α-helix	trans	-64.1	-43.2	176	-169	165.7	-153.7	0	0	111.2	E80 C87 E88 T122	E80-E84 WeakPolarHBondContact O-CB 3.19Å; E80-E84 PolarHBondContact O-N 2.85Å; E84-C87 WeakPolarHBondContact O-CB 3.27Å; E84-C87 PolarHBondContact O-N 2.89Å; E84-E88 WeakPolarHBondContact O-CG 3.27Å; E84-E88 PolarHBondContact O-N 3.32Å; E84-T122 HydrophobicContact CB-CG2 4.16Å; E84-T122 HydrophobicContact CG-CG2 4.11Å
85	S	56.1	Low	49.4	Very low	52 Å²	52	82.6 Å²	82.6	36%	0.364	40%	0.401	S	S	.	.	H	α-helix	trans	-61.7	-45.1	173.3	-176.3	0	0	0	0	112.3	A81 C87 E88 K89	A81-S85 WeakPolarHBondContact O-CB 3.45Å; A81-S85 PolarHBondContact O-N 3.34Å; S85-C87 VanDerWaalsContact C-N 3.34Å; S85-C87 PolarHBondContact O-N 3.03Å; S85-E88 PolarHBondContact O-N 2.95Å; S85-K89 WeakPolarHBondContact O-CB 3.43Å; S85-K89 WeakPolarHBondContact O-CG 3.49Å; S85-K89 PolarHBondContact O-N 3.27Å
86	L	55.7	Low	49.4	Very low	27 Å²	27	79.1 Å²	79.1	14%	0.141	40%	0.403	C	S	.	.	H	α-helix	trans	-62.8	-42.3	175.5	-174.4	68.8	0	0	0	111.1	I46 L71 L82 I83 K89 L90 L109	I46-L86 HydrophobicContact CG2-CD1 4.07Å; L71-L86 HydrophobicContact CD1-CD2 4.18Å; L82-L86 VanDerWaalsContact O-CB 3.28Å; L82-L86 WeakPolarHBondContact O-CB 3.37Å; L82-L86 PolarHBondContact O-N 3.08Å; I83-L86 PolarHBondContact O-N 3.28Å; L86-K89 PolarHBondContact O-N 3.43Å; L86-L90 HydrophobicContact CG-CD1 4.02Å; L86-L90 HydrophobicContact CG-CG 4.43Å; L86-L90 WeakPolarHBondContact O-CB 3.15Å; L86-L90 WeakPolarHBondContact O-CG 3.45Å; L86-L90 PolarHBondContact O-N 3.19Å; L86-L109 HydrophobicContact CD2-CD1 4.39Å
87	C	52.9	Low	49	Very low	4 Å²	4	84.1 Å²	84.1	3%	0.027	42%	0.42	C	S	.	.	H	α-helix	trans	-63.1	-45.8	177.4	-79.8	0	0	0	0	112.4	I83 E84 S85 K89 L90 V91 S126	I83-C87 WeakPolarHBondContact O-CB 3.29Å; I83-C87 PolarHBondContact O-N 3.06Å; I83-C87 PolarHBondContact O-SG 3.17Å; E84-C87 WeakPolarHBondContact O-CB 3.27Å; E84-C87 PolarHBondContact O-N 2.89Å; S85-C87 VanDerWaalsContact C-N 3.34Å; S85-C87 PolarHBondContact O-N 3.03Å; C87-K89 VanDerWaalsContact C-N 3.3Å; C87-K89 PolarHBondContact O-N 3.21Å; C87-L90 PolarHBondContact O-N 3.47Å; C87-V91 WeakPolarHBondContact O-CB 3.43Å; C87-V91 VanDerWaalsContact O-CG2 3.24Å; C87-V91 WeakPolarHBondContact O-CG2 3.44Å; C87-V91 PolarHBondContact O-N 2.81Å; C87-S126 WeakPolarHBondContact CB-OG 3.44Å; C87-S126 WeakPolarHBondContact SG-CB 3.34Å; C87-S126 PolarHBondContact SG-OG 3.08Å; C87-S126 VanDerWaalsContact SG-OG 3.35Å
88	E	55.6	Low	49.3	Very low	119 Å²	119	80.1 Å²	80.1	56%	0.556	40%	0.398	S	S	*	.	H	α-helix	trans	-62.8	-38.1	176	-76.1	-167.2	163.6	0	0	112	E84 S85 V91 K92	E84-E88 WeakPolarHBondContact O-CG 3.27Å; E84-E88 PolarHBondContact O-N 3.32Å; S85-E88 PolarHBondContact O-N 2.95Å; E88-V91 PolarHBondContact O-N 3.32Å; E88-K92 PolarHBondContact O-N 2.83Å
89	K	55.2	Low	49.4	Very low	32 Å²	32	77.3 Å²	77.3	14%	0.139	39%	0.39	C	S	.	.	H	α-helix	trans	-69.6	-44	175.7	-73	-171.4	176.9	-149	0	112.1	I46 E47 D50 S85 L86 C87 V91 K92 F93	I46-K89 HydrophobicContact CG2-CD 4.46Å; E47-K89 IonicContact OE1-NZ 2.87Å; E47-K89 PolarHBondContact OE1-NZ 3.24Å; D50-K89 IonicContact OD2-NZ 3.08Å; S85-K89 WeakPolarHBondContact O-CB 3.43Å; S85-K89 WeakPolarHBondContact O-CG 3.49Å; S85-K89 PolarHBondContact O-N 3.27Å; L86-K89 PolarHBondContact O-N 3.43Å; C87-K89 VanDerWaalsContact C-N 3.3Å; C87-K89 PolarHBondContact O-N 3.21Å; K89-V91 PolarHBondContact O-N 3.14Å; K89-K92 PolarHBondContact O-N 2.66Å; K89-F93 VanDerWaalsContact O-CD2 3.3Å; K89-F93 WeakPolarHBondContact O-CD2 3.29Å; K89-F93 PolarHBondContact O-N 3.46Å
90	L	51.7	Low	49.4	Very low	31 Å²	31	80.2 Å²	80.2	16%	0.162	41%	0.413	C	S	.	.	H	α-helix	trans	-59.4	-31.5	173.9	-72.4	170.5	0	0	0	112.6	L86 C87	L86-L90 HydrophobicContact CG-CD1 4.02Å; L86-L90 HydrophobicContact CG-CG 4.43Å; L86-L90 WeakPolarHBondContact O-CB 3.15Å; L86-L90 WeakPolarHBondContact O-CG 3.45Å; L86-L90 PolarHBondContact O-N 3.19Å; C87-L90 PolarHBondContact O-N 3.47Å
91	V	52.2	Low	49.5	Very low	58 Å²	58	77.3 Å²	77.3	35%	0.352	40%	0.4	S	S	.	.	H	α-helix	trans	-77.2	-30.9	173.8	172	0	0	0	0	112.5	C87 E88 K89 K129	C87-V91 WeakPolarHBondContact O-CB 3.43Å; C87-V91 VanDerWaalsContact O-CG2 3.24Å; C87-V91 WeakPolarHBondContact O-CG2 3.44Å; C87-V91 PolarHBondContact O-N 2.81Å; E88-V91 PolarHBondContact O-N 3.32Å; K89-V91 PolarHBondContact O-N 3.14Å; V91-K129 HydrophobicContact CG2-CB 4.18Å; V91-K129 HydrophobicContact CG2-CD 4.3Å
92	K	50	Low	49.5	Very low	166 Å²	166	76.6 Å²	76.6	72%	0.722	38%	0.383	S	S	*	.	H	α-helix	trans	-71.2	-27.4	176.7	-86.7	177.9	176.9	169.9	0	113.6	E88 K89 R94	E88-K92 PolarHBondContact O-N 2.83Å; K89-K92 PolarHBondContact O-N 2.66Å; K92-R94 PolarHBondContact O-N 3.1Å
93	F	40.9	Very low	49.6	Very low	77 Å²	77	76.5 Å²	76.5	34%	0.338	38%	0.382	S	S	.	.			trans	-75.9	95.9	175.3	-79.7	-84.4	0	0	0	112	D50 K89 R102	D50-F93 HydrophobicContact CB-CE2 4.49Å; D50-F93 HydrophobicContact CB-CZ 3.99Å; D50-F93 WeakPolarHBondContact OD1-CE2 3.42Å; D50-F93 WeakPolarHBondContact OD1-CZ 3.4Å; K89-F93 VanDerWaalsContact O-CD2 3.3Å; K89-F93 WeakPolarHBondContact O-CD2 3.29Å; K89-F93 PolarHBondContact O-N 3.46Å; F93-R102 PolarHBondContact O-NH1 3.16Å; F93-R102 PolarHBondContact O-NH2 2.87Å
94	R	44	Very low	49.6	Very low	210 Å²	210	81.3 Å²	81.3	79%	0.792	40%	0.404	S	S	*	.			trans	-108.7	19.4	-179.3	-140.7	-167.9	-86.8	-163.8	-3.9	114.3	K92	K92-R94 PolarHBondContact O-N 3.1Å
95	E	31	Very low	49.5	Very low	176 Å²	176	77.3 Å²	77.3	82%	0.822	39%	0.386	S	S	*	.	S	Bend	trans	-106	121.8	176.4	-66.5	-150.3	148	0	0	112.6
96	G	40.8	Very low	49.6	Very low	68 Å²	68	75 Å²	75	70%	0.701	37%	0.37	S	S	*	.	S	Bend	trans	44.9	107.3	149.2	0	0	0	0	0	118.1
97	E	37.9	Very low	49.6	Very low	179 Å²	179	75.8 Å²	75.8	84%	0.836	38%	0.378	S	S	*	.	S	Bend	trans	67.4	60.1	149.8	-112.3	-178.9	161.8	0	0	116.6
98	R	45.2	Very low	49.8	Very low	90 Å²	90	78.5 Å²	78.5	34%	0.34	39%	0.392	S	S	.	.			trans	-165.7	60.2	141.9	-100.5	157	-64.3	165.5	1.9	115.1	D57 L101 R102	D57-R98 WeakPolarHBondContact OD1-CD 3.48Å; D57-R98 IonicContact OD1-CZ 2.91Å; D57-R98 IonicContact OD1-NE 2.65Å; D57-R98 IonicContact OD1-NH1 3.4Å; D57-R98 PolarHBondContact OD1-NH1 3.34Å; R98-L101 HydrophobicContact CB-CB 4.29Å; R98-L101 HydrophobicContact CG-CB 4.35Å; R98-R102 WeakPolarHBondContact O-CG 3.33Å
99	P	50.6	Low	49.9	Very low	44 Å²	44	73.4 Å²	73.4	29%	0.286	37%	0.368	S	S	.	.	H	α-helix	trans	-49.9	-46.5	163.4	-36.7	43	0	0	0	116.2	R102 L103 C134	P99-R102 PolarHBondContact O-N 3.26Å; P99-L103 WeakPolarHBondContact O-CG 3.03Å; P99-L103 PolarHBondContact O-N 2.89Å; P99-C134 WeakPolarHBondContact CA-SG 3.48Å; P99-C134 HydrophobicContact CB-CB 3.65Å; P99-C134 WeakPolarHBondContact CB-SG 3.3Å; P99-C134 HydrophobicContact CG-CB 4.22Å
100	S	48.3	Very low	49.9	Very low	84 Å²	84	72.9 Å²	72.9	59%	0.587	37%	0.366	S	S	*	.	H	α-helix	trans	-71.9	-38.9	-166.7	-49	0	0	0	0	112.3	R102 L103 Q104	S100-R102 VanDerWaalsContact C-N 3.33Å; S100-R102 PolarHBondContact O-N 2.81Å; S100-L103 PolarHBondContact O-N 2.98Å; S100-Q104 WeakPolarHBondContact O-CB 3.45Å; S100-Q104 PolarHBondContact O-N 2.91Å
101	L	52.3	Low	50.2	Low	15 Å²	15	78.2 Å²	78.2	8%	0.079	39%	0.39	C	S	.	.	H	α-helix	trans	-59.8	-45.9	174.1	-152.3	87.7	0	0	0	110.8	V60 E61 M64 R98 L103 Q104 L105	V60-L101 HydrophobicContact CG1-CD2 4.04Å; E61-L101 HydrophobicContact CG-CD1 3.38Å; E61-L101 HydrophobicContact CG-CG 4.3Å; E61-L101 WeakPolarHBondContact OE1-CD1 3.25Å; M64-L101 HydrophobicContact SD-CD2 4.42Å; R98-L101 HydrophobicContact CB-CB 4.29Å; R98-L101 HydrophobicContact CG-CB 4.35Å; L101-L103 VanDerWaalsContact C-N 3.35Å; L101-L103 PolarHBondContact O-N 3.43Å; L101-Q104 PolarHBondContact O-N 3.5Å; L101-L105 HydrophobicContact CD2-CD1 4.16Å; L101-L105 HydrophobicContact CG-CD1 4.09Å; L101-L105 WeakPolarHBondContact O-CB 3.34Å; L101-L105 WeakPolarHBondContact O-CD1 3.49Å; L101-L105 WeakPolarHBondContact O-CG 3.49Å; L101-L105 PolarHBondContact O-N 3.18Å
102	R	54.2	Low	49.8	Very low	51 Å²	51	76.8 Å²	76.8	19%	0.192	39%	0.387	C	S	.	.	H	α-helix	trans	-64.6	-40.8	179.2	-63.1	172.7	-171.9	176.3	2.6	111.3	F93 R98 P99 S100 L106 V130	F93-R102 PolarHBondContact O-NH1 3.16Å; F93-R102 PolarHBondContact O-NH2 2.87Å; R98-R102 WeakPolarHBondContact O-CG 3.33Å; P99-R102 PolarHBondContact O-N 3.26Å; S100-R102 VanDerWaalsContact C-N 3.33Å; S100-R102 PolarHBondContact O-N 2.81Å; R102-L106 WeakPolarHBondContact O-CB 3.49Å; R102-L106 PolarHBondContact O-N 3.27Å; R102-V130 HydrophobicContact CB-CG1 3.9Å
103	L	55.3	Low	49.7	Very low	18 Å²	18	69.8 Å²	69.8	9%	0.094	36%	0.357	C	S	.	.	H	α-helix	trans	-66	-40.4	175.4	-72.2	169.9	0	0	0	111.7	P99 S100 L101 S107 L127 C134 A136	P99-L103 WeakPolarHBondContact O-CG 3.03Å; P99-L103 PolarHBondContact O-N 2.89Å; S100-L103 PolarHBondContact O-N 2.98Å; L101-L103 VanDerWaalsContact C-N 3.35Å; L101-L103 PolarHBondContact O-N 3.43Å; L103-S107 WeakPolarHBondContact O-CB 3.36Å; L103-S107 PolarHBondContact O-N 3.45Å; L103-L127 HydrophobicContact CD2-CD1 4.32Å; L103-C134 HydrophobicContact CD1-CB 4.33Å; L103-A136 HydrophobicContact CD1-CB 4.19Å
104	Q	54.3	Low	49.7	Very low	105 Å²	105	72.9 Å²	72.9	49%	0.491	38%	0.377	S	S	.	.	H	α-helix	trans	-70.2	-42.3	179.5	-170.3	173.3	-24.1	0	0	111.9	S100 L101 S107 N108	S100-Q104 WeakPolarHBondContact O-CB 3.45Å; S100-Q104 PolarHBondContact O-N 2.91Å; L101-Q104 PolarHBondContact O-N 3.5Å; Q104-S107 PolarHBondContact O-N 3.11Å; Q104-N108 WeakPolarHBondContact O-CB 2.86Å; Q104-N108 PolarHBondContact O-N 3.37Å; Q104-N108 PolarHBondContact O-OD1 3.36Å
105	L	55.5	Low	49.8	Very low	18 Å²	18	69.3 Å²	69.3	9%	0.094	37%	0.369	C	S	.	.	H	α-helix	trans	-65.4	-42.4	175.6	-70.9	164.5	0	0	0	112.1	M64 L101 S107 N108 L109	M64-L105 HydrophobicContact CB-CD1 4Å; M64-L105 HydrophobicContact CB-CD2 3.46Å; M64-L105 VanDerWaalsContact CB-CD2 3.46Å; M64-L105 HydrophobicContact CB-CG 4.36Å; M64-L105 HydrophobicContact CE-CD1 4.41Å; M64-L105 HydrophobicContact CG-CD1 4.21Å; M64-L105 HydrophobicContact SD-CD1 3.14Å; M64-L105 WeakPolarHBondContact SD-CD1 3.35Å; M64-L105 HydrophobicContact SD-CD2 4.44Å; M64-L105 HydrophobicContact SD-CG 4.38Å; L101-L105 HydrophobicContact CD2-CD1 4.16Å; L101-L105 HydrophobicContact CG-CD1 4.09Å; L101-L105 WeakPolarHBondContact O-CB 3.34Å; L101-L105 WeakPolarHBondContact O-CD1 3.49Å; L101-L105 WeakPolarHBondContact O-CG 3.49Å; L101-L105 PolarHBondContact O-N 3.18Å; L105-S107 VanDerWaalsContact C-N 3.33Å; L105-N108 PolarHBondContact O-N 2.62Å; L105-L109 WeakPolarHBondContact O-CB 2.94Å; L105-L109 VanDerWaalsContact O-CG 3.32Å; L105-L109 WeakPolarHBondContact O-CG 3.45Å; L105-L109 PolarHBondContact O-N 2.76Å
106	L	57.1	Low	50.1	Low	4 Å²	4	67 Å²	67	2%	0.021	36%	0.362	C	S	.	.	H	α-helix	trans	-74.7	-28.2	179.1	-159.4	55.9	0	0	0	111.8	R102 L109 F110 V123 L127	R102-L106 WeakPolarHBondContact O-CB 3.49Å; R102-L106 PolarHBondContact O-N 3.27Å; L106-L109 HydrophobicContact CD1-CD1 4.13Å; L106-F110 VanDerWaalsContact O-CB 3.23Å; L106-F110 WeakPolarHBondContact O-CB 3.43Å; L106-F110 PolarHBondContact O-N 3.22Å; L106-V123 HydrophobicContact CD1-CG1 3.68Å; L106-V123 HydrophobicContact CG-CG1 4.29Å; L106-L127 HydrophobicContact CB-CD1 3.66Å; L106-L127 HydrophobicContact CD2-CB 3.57Å; L106-L127 HydrophobicContact CD2-CD1 3.6Å; L106-L127 HydrophobicContact CD2-CG 4.14Å; L106-L127 HydrophobicContact CG-CB 3.95Å; L106-L127 HydrophobicContact CG-CD1 3.51Å; L106-L127 HydrophobicContact CG-CG 4.33Å
107	S	56.4	Low	50.4	Low	43 Å²	43	65.6 Å²	65.6	30%	0.301	34%	0.341	S	S	.	.	H	α-helix	trans	-68	-43.3	167.8	-168.4	0	0	0	0	111.2	L103 Q104 L105 L109 F110 H111	L103-S107 WeakPolarHBondContact O-CB 3.36Å; L103-S107 PolarHBondContact O-N 3.45Å; Q104-S107 PolarHBondContact O-N 3.11Å; L105-S107 VanDerWaalsContact C-N 3.33Å; S107-L109 VanDerWaalsContact C-N 3.35Å; S107-L109 PolarHBondContact O-N 2.93Å; S107-F110 PolarHBondContact O-N 2.86Å; S107-F110 VanDerWaalsContact O-N 3.16Å; S107-H111 WeakPolarHBondContact O-CB 3.35Å; S107-H111 PolarHBondContact O-N 2.9Å; S107-H111 PolarHBondContact O-ND1 2.76Å; S107-H111 PolarHBondContact OG-CE1 3.24Å; S107-H111 PolarHBondContact OG-ND1 2.84Å
108	N	58.1	Low	51	Low	60 Å²	60	59.7 Å²	59.7	32%	0.321	32%	0.317	S	S	.	.	H	α-helix	trans	-63.6	-41.2	175.5	-71.2	-9.2	0	0	0	111.2	N65 Q104 L105 F110 G112	N65-N108 PolarHBondContact OD1-ND2 3.25Å; Q104-N108 WeakPolarHBondContact O-CB 2.86Å; Q104-N108 PolarHBondContact O-N 3.37Å; Q104-N108 PolarHBondContact O-OD1 3.36Å; L105-N108 PolarHBondContact O-N 2.62Å; N108-F110 VanDerWaalsContact C-N 3.34Å; N108-G112 WeakPolarHBondContact O-CA 3.16Å; N108-G112 PolarHBondContact O-N 2.86Å
109	L	56.2	Low	51.4	Low	13 Å²	13	55.5 Å²	55.5	7%	0.068	30%	0.302	C	S	.	.	H	α-helix	trans	-62.5	-40.3	171.5	-75.7	165.9	0	0	0	111.9	V68 L71 L86 L105 L106 S107 G112 M113	V68-L109 HydrophobicContact CB-CD2 4.25Å; V68-L109 HydrophobicContact CG1-CD2 3.92Å; V68-L109 HydrophobicContact CG1-CG 4.23Å; V68-L109 HydrophobicContact CG2-CD1 4.3Å; V68-L109 HydrophobicContact CG2-CD2 3.78Å; V68-L109 HydrophobicContact CG2-CG 3.77Å; L71-L109 HydrophobicContact CD1-CD2 4.42Å; L86-L109 HydrophobicContact CD2-CD1 4.39Å; L105-L109 WeakPolarHBondContact O-CB 2.94Å; L105-L109 VanDerWaalsContact O-CG 3.32Å; L105-L109 WeakPolarHBondContact O-CG 3.45Å; L105-L109 PolarHBondContact O-N 2.76Å; L106-L109 HydrophobicContact CD1-CD1 4.13Å; S107-L109 VanDerWaalsContact C-N 3.35Å; S107-L109 PolarHBondContact O-N 2.93Å; L109-G112 PolarHBondContact O-N 2.8Å; L109-M113 WeakPolarHBondContact O-CE 3.47Å; L109-M113 WeakPolarHBondContact O-CG 3.13Å; L109-M113 PolarHBondContact O-N 3.45Å
110	F	56.6	Low	51.5	Low	20 Å²	20	54.4 Å²	54.4	9%	0.088	29%	0.292	C	S	.	.	H	α-helix	trans	-67.9	-43.5	179	-173	-95.3	0	0	0	112.7	L106 S107 N108 G112 R120 V123 W150 W154	L106-F110 VanDerWaalsContact O-CB 3.23Å; L106-F110 WeakPolarHBondContact O-CB 3.43Å; L106-F110 PolarHBondContact O-N 3.22Å; S107-F110 PolarHBondContact O-N 2.86Å; S107-F110 VanDerWaalsContact O-N 3.16Å; N108-F110 VanDerWaalsContact C-N 3.34Å; F110-G112 VanDerWaalsContact C-N 3.27Å; F110-R120 HydrophobicContact CE2-CB 4.42Å; F110-R120 HydrophobicContact CE2-CG 4.37Å; F110-V123 HydrophobicContact CD2-CG1 4.49Å; F110-W150 AromaticContact CE1-CH2 3.6Å; F110-W150 HydrophobicContact CE1-CH2 3.6Å; F110-W150 AromaticContact CE1-CZ2 3.4Å; F110-W150 HydrophobicContact CE1-CZ2 3.4Å; F110-W150 HydrophobicContact CE1-CZ3 4.41Å; F110-W150 HydrophobicContact CE2-CH2 4.45Å; F110-W150 HydrophobicContact CE2-CZ3 4.5Å; F110-W150 HydrophobicContact CZ-CD2 4.04Å; F110-W150 AromaticContact CZ-CE2 3.64Å; F110-W150 HydrophobicContact CZ-CE3 4.07Å; F110-W150 AromaticContact CZ-CH2 3.4Å; F110-W150 HydrophobicContact CZ-CH2 3.4Å; F110-W150 AromaticContact CZ-CZ2 3.34Å; F110-W150 HydrophobicContact CZ-CZ2 3.34Å; F110-W150 AromaticContact CZ-CZ3 3.76Å; F110-W150 HydrophobicContact CZ-CZ3 3.76Å; F110-W154 HydrophobicContact CE2-CH2 4.38Å; F110-W154 HydrophobicContact CE2-CZ2 4.43Å
111	H	56.6	Low	51.7	Low	144 Å²	144	51.6 Å²	51.6	67%	0.667	27%	0.269	S	S	*	.	H	α-helix	trans	-76.5	-15.8	177	-66.1	99.8	0	0	0	113.1	S107	S107-H111 WeakPolarHBondContact O-CB 3.35Å; S107-H111 PolarHBondContact O-N 2.9Å; S107-H111 PolarHBondContact O-ND1 2.76Å; S107-H111 PolarHBondContact OG-CE1 3.24Å; S107-H111 PolarHBondContact OG-ND1 2.84Å
112	G	43.9	Very low	51.9	Low	27 Å²	27	52.5 Å²	52.5	28%	0.278	28%	0.275	S	S	.	.	H	α-helix	trans	-87.1	-17.2	-179.5	0	0	0	0	0	115.6	L72 N108 L109 F110	L72-G112 VanDerWaalsContact CD1-CA 3.44Å; L72-G112 WeakPolarHBondContact CD1-O 3.16Å; L72-G112 WeakPolarHBondContact CG-O 3.44Å; N108-G112 WeakPolarHBondContact O-CA 3.16Å; N108-G112 PolarHBondContact O-N 2.86Å; L109-G112 PolarHBondContact O-N 2.8Å; F110-G112 VanDerWaalsContact C-N 3.27Å
113	M	49.5	Very low	52	Low	19 Å²	19	50.2 Å²	50.2	9%	0.094	27%	0.267	C	S	.	.	S	Bend	trans	-96.4	144.2	-178.9	-66.4	-176.8	-65.8	0	0	112.3	I83 L109 V119 R120 V123	I83-M113 HydrophobicContact CD1-SD 3.97Å; L109-M113 WeakPolarHBondContact O-CE 3.47Å; L109-M113 WeakPolarHBondContact O-CG 3.13Å; L109-M113 PolarHBondContact O-N 3.45Å; M113-V119 HydrophobicContact CE-CG1 4.3Å; M113-V119 HydrophobicContact SD-CB 4.22Å; M113-V119 HydrophobicContact SD-CG1 3.48Å; M113-V119 WeakPolarHBondContact SD-CG1 3.49Å; M113-R120 HydrophobicContact CE-CG 3.9Å; M113-R120 PolarHBondContact O-NE 3.47Å; M113-R120 PolarHBondContact O-NH2 3.07Å; M113-V123 HydrophobicContact CE-CB 3.86Å; M113-V123 HydrophobicContact CE-CG1 3.94Å; M113-V123 HydrophobicContact CE-CG2 3.57Å; M113-V123 HydrophobicContact SD-CG2 4.33Å
114	D	40.7	Very low	52.1	Low	142 Å²	142	49.7 Å²	49.7	76%	0.759	26%	0.264	S	S	*	.			trans	-70.7	161.1	177.4	-92.3	-44.5	0	0	0	114.6	N116	D114-N116 VanDerWaalsContact C-N 3.31Å; D114-N116 PolarHBondContact O-N 2.85Å; D114-N116 VanDerWaalsContact O-N 3.09Å
115	E	44.5	Very low	52.2	Low	135 Å²	135	45.2 Å²	45.2	63%	0.631	24%	0.244	S	C	*	.	T	Hydrogen-bonded Turn	trans	-69.1	-3.9	-159	-74.5	179.4	152	0	0	118.3
116	N	38.7	Very low	52.1	Low	127 Å²	127	44.9 Å²	44.9	68%	0.679	24%	0.243	S	C	*	.	T	Hydrogen-bonded Turn	trans	-126.2	5	-162.7	-119.6	-36.7	0	0	0	117.5	D114 D153	D114-N116 VanDerWaalsContact C-N 3.31Å; D114-N116 PolarHBondContact O-N 2.85Å; D114-N116 VanDerWaalsContact O-N 3.09Å; N116-D153 PolarHBondContact OD1-O 3.31Å
117	T	46.2	Very low	52.2	Low	40 Å²	40	45.4 Å²	45.4	25%	0.245	25%	0.246	C	C	.	.			trans	-104.2	136.7	-172	-36.2	0	0	0	0	113.2	V119 R120	T117-V119 HydrophobicContact CG2-CB 4.29Å; T117-V119 HydrophobicContact CG2-CG2 3.65Å; T117-V119 PolarHBondContact O-N 3.04Å; T117-R120 PolarHBondContact O-N 3.07Å; T117-R120 VanDerWaalsContact O-N 3.1Å
118	P	50.6	Low	52.4	Low	54 Å²	54	43.7 Å²	43.7	35%	0.351	23%	0.233	S	C	.	.	T	Hydrogen-bonded Turn	trans	-52.1	-13.1	170.7	14.6	-28.2	0	0	0	115.2	R120 Y121 L156	P118-R120 VanDerWaalsContact C-N 3.31Å; P118-R120 PolarHBondContact O-N 2.95Å; P118-Y121 VanDerWaalsContact O-CB 3.24Å; P118-Y121 WeakPolarHBondContact O-CB 3.01Å; P118-Y121 PolarHBondContact O-N 2.84Å; P118-Y121 VanDerWaalsContact O-N 3.11Å; P118-L156 HydrophobicContact CB-CD1 3.92Å; P118-L156 HydrophobicContact CB-CD2 4.19Å
119	V	53.2	Low	52.4	Low	2 Å²	2	45.4 Å²	45.4	1%	0.012	24%	0.238	C	C	.	.	H	α-helix	trans	-57.7	-37.5	171.5	-174.7	0	0	0	0	113.3	E80 I83 M113 T117 Y121 T122 V123	E80-V119 HydrophobicContact CB-CG2 3.9Å; E80-V119 HydrophobicContact CG-CG2 3.37Å; E80-V119 WeakPolarHBondContact OE1-CG2 3.42Å; I83-V119 HydrophobicContact CB-CG1 4.37Å; I83-V119 HydrophobicContact CD1-CG1 3.4Å; I83-V119 HydrophobicContact CG1-CG1 4.47Å; I83-V119 HydrophobicContact CG2-CG1 4.1Å; M113-V119 HydrophobicContact CE-CG1 4.3Å; M113-V119 HydrophobicContact SD-CB 4.22Å; M113-V119 HydrophobicContact SD-CG1 3.48Å; M113-V119 WeakPolarHBondContact SD-CG1 3.49Å; T117-V119 HydrophobicContact CG2-CB 4.29Å; T117-V119 HydrophobicContact CG2-CG2 3.65Å; T117-V119 PolarHBondContact O-N 3.04Å; V119-Y121 PolarHBondContact O-N 3.36Å; V119-T122 PolarHBondContact O-N 2.77Å; V119-T122 VanDerWaalsContact O-N 3.13Å; V119-V123 HydrophobicContact CG1-CG2 4.19Å; V119-V123 WeakPolarHBondContact O-CG2 3.17Å; V119-V123 PolarHBondContact O-N 3.36Å
120	R	53.4	Low	52.3	Low	22 Å²	22	44.9 Å²	44.9	8%	0.083	24%	0.235	C	C	.	.	H	α-helix	trans	-62.3	-28.8	176.6	-78.2	-166.7	-172.7	160.2	0.3	111.9	F110 M113 T117 P118 F124 W154	F110-R120 HydrophobicContact CE2-CB 4.42Å; F110-R120 HydrophobicContact CE2-CG 4.37Å; M113-R120 HydrophobicContact CE-CG 3.9Å; M113-R120 PolarHBondContact O-NE 3.47Å; M113-R120 PolarHBondContact O-NH2 3.07Å; T117-R120 PolarHBondContact O-N 3.07Å; T117-R120 VanDerWaalsContact O-N 3.1Å; P118-R120 VanDerWaalsContact C-N 3.31Å; P118-R120 PolarHBondContact O-N 2.95Å; R120-F124 WeakPolarHBondContact O-CB 3.12Å; R120-F124 PolarHBondContact O-N 3.34Å; R120-W154 HydrophobicContact CB-CD2 4.49Å; R120-W154 HydrophobicContact CB-CH2 3.66Å; R120-W154 HydrophobicContact CB-CZ2 3.25Å; R120-W154 HydrophobicContact CB-CZ3 4.41Å; R120-W154 HydrophobicContact CG-CZ2 3.96Å
121	Y	53.4	Low	52	Low	24 Å²	24	44 Å²	44	9%	0.094	23%	0.232	C	C	.	.	H	α-helix	trans	-66	-44.8	174.8	170.8	-88.4	0	0	0	111.8	P118 V119 F124 C125 L156 K160 L164	P118-Y121 VanDerWaalsContact O-CB 3.24Å; P118-Y121 WeakPolarHBondContact O-CB 3.01Å; P118-Y121 PolarHBondContact O-N 2.84Å; P118-Y121 VanDerWaalsContact O-N 3.11Å; V119-Y121 PolarHBondContact O-N 3.36Å; Y121-F124 PolarHBondContact O-N 2.95Å; Y121-C125 VanDerWaalsContact CZ-SG 3.56Å; Y121-C125 WeakPolarHBondContact O-CB 3.48Å; Y121-C125 PolarHBondContact O-N 3.33Å; Y121-C125 PolarHBondContact O-SG 2.96Å; Y121-L156 HydrophobicContact CG-CD2 4.4Å; Y121-K160 HydrophobicContact CD1-CD 4.39Å; Y121-K160 HydrophobicContact CD2-CB 4.35Å; Y121-K160 HydrophobicContact CE1-CB 4.04Å; Y121-K160 HydrophobicContact CE1-CD 4.06Å; Y121-K160 HydrophobicContact CE1-CG 4.08Å; Y121-K160 HydrophobicContact CE2-CB 3.63Å; Y121-K160 WeakPolarHBondContact CE2-O 3.39Å; Y121-K160 VanDerWaalsContact CZ-CB 3.49Å; Y121-K160 WeakPolarHBondContact OH-CA 3.39Å; Y121-K160 PolarHBondContact OH-O 2.76Å; Y121-L164 HydrophobicContact CD2-CB 4.12Å; Y121-L164 HydrophobicContact CD2-CD2 3.96Å; Y121-L164 HydrophobicContact CE2-CB 3.41Å; Y121-L164 VanDerWaalsContact CE2-CB 3.41Å; Y121-L164 HydrophobicContact CE2-CD2 4.1Å; Y121-L164 HydrophobicContact CE2-CG 4.26Å
122	T	55	Low	51.8	Low	35 Å²	35	38.2 Å²	38.2	22%	0.215	21%	0.209	C	C	.	.	H	α-helix	trans	-69.1	-41.4	178.7	-54.1	0	0	0	0	111.6	E84 V119 C125 S126	E84-T122 HydrophobicContact CB-CG2 4.16Å; E84-T122 HydrophobicContact CG-CG2 4.11Å; V119-T122 PolarHBondContact O-N 2.77Å; V119-T122 VanDerWaalsContact O-N 3.13Å; T122-C125 PolarHBondContact O-N 3.3Å; T122-S126 WeakPolarHBondContact O-CB 3.31Å; T122-S126 PolarHBondContact O-N 3.28Å; T122-S126 VanDerWaalsContact O-N 3.07Å; T122-S126 PolarHBondContact O-OG 2.87Å
123	V	56.7	Low	52.1	Low	3 Å²	3	41.3 Å²	41.3	2%	0.018	22%	0.222	C	C	.	.	H	α-helix	trans	-63.5	-43.3	174.5	171.5	0	0	0	0	111.1	I83 L106 F110 M113 V119 S126 L127	I83-V123 HydrophobicContact CG2-CG2 3.28Å; L106-V123 HydrophobicContact CD1-CG1 3.68Å; L106-V123 HydrophobicContact CG-CG1 4.29Å; F110-V123 HydrophobicContact CD2-CG1 4.49Å; M113-V123 HydrophobicContact CE-CB 3.86Å; M113-V123 HydrophobicContact CE-CG1 3.94Å; M113-V123 HydrophobicContact CE-CG2 3.57Å; M113-V123 HydrophobicContact SD-CG2 4.33Å; V119-V123 HydrophobicContact CG1-CG2 4.19Å; V119-V123 WeakPolarHBondContact O-CG2 3.17Å; V119-V123 PolarHBondContact O-N 3.36Å; V123-S126 PolarHBondContact O-N 3.34Å; V123-L127 VanDerWaalsContact O-CB 3.32Å; V123-L127 WeakPolarHBondContact O-CB 3.25Å; V123-L127 PolarHBondContact O-N 3.15Å
124	F	57.9	Low	52	Low	7 Å²	7	41.2 Å²	41.2	3%	0.031	22%	0.224	C	C	.	.	H	α-helix	trans	-71	-37.8	178.8	-173	-113.5	0	0	0	112	R120 Y121 S126 L127 V128 V147 W150 L164 V168	R120-F124 WeakPolarHBondContact O-CB 3.12Å; R120-F124 PolarHBondContact O-N 3.34Å; Y121-F124 PolarHBondContact O-N 2.95Å; F124-S126 PolarHBondContact O-N 2.77Å; F124-L127 HydrophobicContact CD2-CD2 3.82Å; F124-L127 HydrophobicContact CE2-CD2 4.16Å; F124-L127 WeakPolarHBondContact O-CB 3.31Å; F124-L127 PolarHBondContact O-N 3.28Å; F124-V128 HydrophobicContact CD1-CG2 4.3Å; F124-V128 HydrophobicContact CD2-CG2 4.41Å; F124-V128 HydrophobicContact CE1-CG2 4Å; F124-V128 HydrophobicContact CE2-CG2 4.15Å; F124-V128 HydrophobicContact CG-CG2 4.46Å; F124-V128 HydrophobicContact CZ-CG2 3.91Å; F124-V128 WeakPolarHBondContact O-CB 3.46Å; F124-V128 WeakPolarHBondContact O-CG2 3.43Å; F124-V128 PolarHBondContact O-N 2.98Å; F124-V147 HydrophobicContact CZ-CG2 4.47Å; F124-W150 HydrophobicContact CD2-CZ3 4.31Å; F124-W150 AromaticContact CE2-CZ3 3.96Å; F124-W150 HydrophobicContact CE2-CZ3 3.96Å; F124-W150 HydrophobicContact CZ-CZ3 4.35Å; F124-L164 HydrophobicContact CD1-CD1 3.16Å; F124-L164 HydrophobicContact CD1-CD2 3.49Å; F124-L164 VanDerWaalsContact CD1-CD2 3.49Å; F124-L164 HydrophobicContact CD1-CG 3.71Å; F124-L164 HydrophobicContact CE1-CD1 3.58Å; F124-L164 HydrophobicContact CE1-CD2 3.78Å; F124-L164 HydrophobicContact CE1-CG 3.85Å; F124-L164 HydrophobicContact CG-CD1 4.18Å; F124-V168 HydrophobicContact CE1-CG2 3.6Å; F124-V168 HydrophobicContact CZ-CG2 3.89Å
125	C	55.5	Low	52.3	Low	11 Å²	11	39.7 Å²	39.7	7%	0.074	22%	0.215	C	C	.	.	H	α-helix	trans	-57.8	-39.8	171	-75.3	0	0	0	0	111.8	Y121 T122 K129 L164 L167	Y121-C125 VanDerWaalsContact CZ-SG 3.56Å; Y121-C125 WeakPolarHBondContact O-CB 3.48Å; Y121-C125 PolarHBondContact O-N 3.33Å; Y121-C125 PolarHBondContact O-SG 2.96Å; T122-C125 PolarHBondContact O-N 3.3Å; C125-K129 WeakPolarHBondContact O-CG 3.37Å; C125-K129 PolarHBondContact O-N 3.4Å; C125-K129 VanDerWaalsContact O-N 3.09Å; C125-L164 HydrophobicContact CB-CD1 4.37Å; C125-L164 WeakPolarHBondContact SG-CD1 3.1Å; C125-L167 HydrophobicContact CB-CD1 4.05Å
126	S	54.6	Low	52.3	Low	10 Å²	10	34.8 Å²	34.8	7%	0.07	20%	0.198	C	C	.	.	H	α-helix	trans	-76.8	-35.5	-180	-55.1	0	0	0	0	111.5	C87 T122 V123 F124 V128 K129 V130	C87-S126 WeakPolarHBondContact CB-OG 3.44Å; C87-S126 WeakPolarHBondContact SG-CB 3.34Å; C87-S126 PolarHBondContact SG-OG 3.08Å; C87-S126 VanDerWaalsContact SG-OG 3.35Å; T122-S126 WeakPolarHBondContact O-CB 3.31Å; T122-S126 PolarHBondContact O-N 3.28Å; T122-S126 VanDerWaalsContact O-N 3.07Å; T122-S126 PolarHBondContact O-OG 2.87Å; V123-S126 PolarHBondContact O-N 3.34Å; F124-S126 PolarHBondContact O-N 2.77Å; S126-V128 VanDerWaalsContact C-N 3.28Å; S126-V128 PolarHBondContact O-N 3.21Å; S126-K129 PolarHBondContact O-N 2.79Å; S126-V130 WeakPolarHBondContact O-CB 3.21Å; S126-V130 VanDerWaalsContact O-CG2 3.25Å; S126-V130 WeakPolarHBondContact O-CG2 3.45Å; S126-V130 PolarHBondContact O-N 3.16Å
127	L	58.9	Low	52.7	Low	16 Å²	16	29.2 Å²	29.2	8%	0.084	17%	0.168	C	C	.	.	H	α-helix	trans	-60.3	-41.7	171.3	-175.3	86	0	0	0	110.9	L103 L106 V123 F124 V130 A131 I140	L103-L127 HydrophobicContact CD2-CD1 4.32Å; L106-L127 HydrophobicContact CB-CD1 3.66Å; L106-L127 HydrophobicContact CD2-CB 3.57Å; L106-L127 HydrophobicContact CD2-CD1 3.6Å; L106-L127 HydrophobicContact CD2-CG 4.14Å; L106-L127 HydrophobicContact CG-CB 3.95Å; L106-L127 HydrophobicContact CG-CD1 3.51Å; L106-L127 HydrophobicContact CG-CG 4.33Å; V123-L127 VanDerWaalsContact O-CB 3.32Å; V123-L127 WeakPolarHBondContact O-CB 3.25Å; V123-L127 PolarHBondContact O-N 3.15Å; F124-L127 HydrophobicContact CD2-CD2 3.82Å; F124-L127 HydrophobicContact CE2-CD2 4.16Å; F124-L127 WeakPolarHBondContact O-CB 3.31Å; F124-L127 PolarHBondContact O-N 3.28Å; L127-V130 PolarHBondContact O-N 2.91Å; L127-A131 WeakPolarHBondContact O-CB 3.27Å; L127-A131 PolarHBondContact O-N 3.32Å; L127-I140 HydrophobicContact CD2-CD1 4.38Å; L127-I140 HydrophobicContact CG-CD1 4.45Å
128	V	60.3	Low	52.5	Low	6 Å²	6	32.8 Å²	32.8	4%	0.036	20%	0.195	C	C	.	.	H	α-helix	trans	-69.3	-41.2	179.2	170.4	0	0	0	0	111.5	F124 S126 A131 A132 L167 V168 A171	F124-V128 HydrophobicContact CD1-CG2 4.3Å; F124-V128 HydrophobicContact CD2-CG2 4.41Å; F124-V128 HydrophobicContact CE1-CG2 4Å; F124-V128 HydrophobicContact CE2-CG2 4.15Å; F124-V128 HydrophobicContact CG-CG2 4.46Å; F124-V128 HydrophobicContact CZ-CG2 3.91Å; F124-V128 WeakPolarHBondContact O-CB 3.46Å; F124-V128 WeakPolarHBondContact O-CG2 3.43Å; F124-V128 PolarHBondContact O-N 2.98Å; S126-V128 VanDerWaalsContact C-N 3.28Å; S126-V128 PolarHBondContact O-N 3.21Å; V128-A131 PolarHBondContact O-N 2.63Å; V128-A132 WeakPolarHBondContact O-CB 3.4Å; V128-A132 PolarHBondContact O-N 2.77Å; V128-L167 HydrophobicContact CG1-CB 3.75Å; V128-L167 WeakPolarHBondContact CG1-O 3.25Å; V128-V168 HydrophobicContact CG1-CG2 4.18Å; V128-V168 HydrophobicContact CG2-CG2 3.65Å; V128-A171 HydrophobicContact CG1-CB 3.69Å
129	K	57.7	Low	52	Low	96 Å²	96	38.7 Å²	38.7	42%	0.417	22%	0.215	S	C	.	.	H	α-helix	trans	-64.6	-39	173.7	-72.4	172.8	-177.7	176.2	0	112.4	V91 C125 S126 T133 L167	V91-K129 HydrophobicContact CG2-CB 4.18Å; V91-K129 HydrophobicContact CG2-CD 4.3Å; C125-K129 WeakPolarHBondContact O-CG 3.37Å; C125-K129 PolarHBondContact O-N 3.4Å; C125-K129 VanDerWaalsContact O-N 3.09Å; S126-K129 PolarHBondContact O-N 2.79Å; K129-T133 PolarHBondContact O-N 3.29Å; K129-T133 PolarHBondContact O-OG1 2.85Å; K129-T133 VanDerWaalsContact O-OG1 3.04Å; K129-L167 HydrophobicContact CG-CD2 4.27Å
130	V	54.6	Low	51.6	Low	3 Å²	3	40 Å²	40	2%	0.018	22%	0.222	C	C	.	.	H	α-helix	trans	-69.6	-40	174.2	172.9	0	0	0	0	110.3	R102 S126 L127 A132 T133 C134	R102-V130 HydrophobicContact CB-CG1 3.9Å; S126-V130 WeakPolarHBondContact O-CB 3.21Å; S126-V130 VanDerWaalsContact O-CG2 3.25Å; S126-V130 WeakPolarHBondContact O-CG2 3.45Å; S126-V130 PolarHBondContact O-N 3.16Å; L127-V130 PolarHBondContact O-N 2.91Å; V130-A132 PolarHBondContact O-N 3.38Å; V130-T133 WeakPolarHBondContact CA-OG1 3.2Å; V130-T133 PolarHBondContact O-N 3.43Å; V130-T133 PolarHBondContact O-OG1 3.34Å; V130-C134 VanDerWaalsContact O-CB 3.23Å; V130-C134 WeakPolarHBondContact O-CB 3.05Å; V130-C134 PolarHBondContact O-N 2.79Å; V130-C134 PolarHBondContact O-SG 3.34Å
131	A	49.5	Very low	50.9	Low	1 Å²	1	42.5 Å²	42.5	1%	0.008	24%	0.241	C	C	.	.	H	α-helix	trans	-64.1	-39.2	176.6	0	0	0	0	0	112.7	L127 V128 T133 C134 N135 I140	L127-A131 WeakPolarHBondContact O-CB 3.27Å; L127-A131 PolarHBondContact O-N 3.32Å; V128-A131 PolarHBondContact O-N 2.63Å; A131-T133 VanDerWaalsContact C-N 3.31Å; A131-T133 PolarHBondContact O-N 3.48Å; A131-C134 PolarHBondContact O-N 2.98Å; A131-N135 PolarHBondContact O-N 3.3Å; A131-N135 VanDerWaalsContact O-N 3.11Å; A131-I140 HydrophobicContact CB-CD1 3.44Å; A131-I140 VanDerWaalsContact CB-CD1 3.44Å
132	A	52.9	Low	50.7	Low	22 Å²	22	43.1 Å²	43.1	18%	0.182	25%	0.247	C	C	.	.	H	α-helix	trans	-59.7	-41.2	174.4	0	0	0	0	0	111.9	V128 V130 C134 A171	V128-A132 WeakPolarHBondContact O-CB 3.4Å; V128-A132 PolarHBondContact O-N 2.77Å; V130-A132 PolarHBondContact O-N 3.38Å; A132-C134 VanDerWaalsContact C-N 3.33Å; A132-A171 HydrophobicContact CB-CB 3.85Å
133	T	50	Low	50.3	Low	92 Å²	92	45.7 Å²	45.7	56%	0.564	26%	0.26	S	S	*	.	H	α-helix	trans	-75.2	-22.7	177	40.1	0	0	0	0	113.3	K129 V130 A131	K129-T133 PolarHBondContact O-N 3.29Å; K129-T133 PolarHBondContact O-OG1 2.85Å; K129-T133 VanDerWaalsContact O-OG1 3.04Å; V130-T133 WeakPolarHBondContact CA-OG1 3.2Å; V130-T133 PolarHBondContact O-N 3.43Å; V130-T133 PolarHBondContact O-OG1 3.34Å; A131-T133 VanDerWaalsContact C-N 3.31Å; A131-T133 PolarHBondContact O-N 3.48Å
134	C	47.2	Very low	49.9	Very low	18 Å²	18	47.2 Å²	47.2	12%	0.122	27%	0.268	C	S	.	.	H	α-helix	trans	-93.8	-15	-174.1	-69.5	0	0	0	0	114.5	P99 L103 V130 A131 A132 A136	P99-C134 WeakPolarHBondContact CA-SG 3.48Å; P99-C134 HydrophobicContact CB-CB 3.65Å; P99-C134 WeakPolarHBondContact CB-SG 3.3Å; P99-C134 HydrophobicContact CG-CB 4.22Å; L103-C134 HydrophobicContact CD1-CB 4.33Å; V130-C134 VanDerWaalsContact O-CB 3.23Å; V130-C134 WeakPolarHBondContact O-CB 3.05Å; V130-C134 PolarHBondContact O-N 2.79Å; V130-C134 PolarHBondContact O-SG 3.34Å; A131-C134 PolarHBondContact O-N 2.98Å; A132-C134 VanDerWaalsContact C-N 3.33Å; C134-A136 PolarHBondContact O-N 3.32Å
135	N	47.6	Very low	49.4	Very low	109 Å²	109	52.2 Å²	52.2	58%	0.583	30%	0.295	S	S	*	.	T	Hydrogen-bonded Turn	trans	48.8	20	-177.1	-106.6	-19.2	0	0	0	114.8	A131 D174 C175	A131-N135 PolarHBondContact O-N 3.3Å; A131-N135 VanDerWaalsContact O-N 3.11Å; N135-D174 PolarHBondContact OD1-O 2.84Å; N135-C175 PolarHBondContact OD1-SG 3.46Å
136	A	45	Very low	49.3	Very low	33 Å²	33	55.1 Å²	55.1	27%	0.273	31%	0.307	S	S	.	.			trans	-115.2	58.3	-173.8	0	0	0	0	0	110.6	L103 C134 S138	L103-A136 HydrophobicContact CD1-CB 4.19Å; C134-A136 PolarHBondContact O-N 3.32Å; A136-S138 PolarHBondContact O-N 2.76Å; A136-S138 VanDerWaalsContact O-N 3.1Å
137	I	46.8	Very low	49.4	Very low	10 Å²	10	55.1 Å²	55.1	5%	0.051	31%	0.307	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80.6	29.5	172.6	-54.4	-176.6	0	0	0	110.9	F139 I140 A171 L172 C175 K177	I137-F139 VanDerWaalsContact C-N 3.34Å; I137-I140 HydrophobicContact CG2-CB 4.36Å; I137-A171 WeakPolarHBondContact CD1-O 3.38Å; I137-L172 HydrophobicContact CD1-CD2 4.38Å; I137-C175 HydrophobicContact CD1-CB 3.58Å; I137-C175 WeakPolarHBondContact CD1-SG 3.45Å; I137-C175 HydrophobicContact CG1-CB 4.13Å; I137-C175 WeakPolarHBondContact CG1-SG 3.29Å; I137-K177 PolarHBondContact O-NZ 2.92Å
138	S	41.3	Very low	49	Very low	115 Å²	115	60.5 Å²	60.5	80%	0.804	33%	0.326	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.7	-19.1	165.7	-60.8	0	0	0	0	111.4	A136	A136-S138 PolarHBondContact O-N 2.76Å; A136-S138 VanDerWaalsContact O-N 3.1Å
139	F	41.2	Very low	48.8	Very low	178 Å²	178	66.8 Å²	66.8	78%	0.781	35%	0.353	S	S	*	.	S	Bend	trans	-105.2	-6.7	-177.5	-97.2	-81.5	0	0	0	115.6	I137 P141	I137-F139 VanDerWaalsContact C-N 3.34Å; F139-P141 WeakPolarHBondContact O-CD 3.25Å
140	I	44	Very low	48.7	Very low	29 Å²	29	64 Å²	64	15%	0.149	34%	0.34	C	S	.	.	S	Bend	trans	-96.2	106.5	170.5	-55.3	174.7	0	0	0	106.4	L127 A131 I137 T142	L127-I140 HydrophobicContact CD2-CD1 4.38Å; L127-I140 HydrophobicContact CG-CD1 4.45Å; A131-I140 HydrophobicContact CB-CD1 3.44Å; A131-I140 VanDerWaalsContact CB-CD1 3.44Å; I137-I140 HydrophobicContact CG2-CB 4.36Å; I140-T142 PolarHBondContact O-N 2.98Å; I140-T142 PolarHBondContact O-OG1 2.83Å; I140-T142 VanDerWaalsContact O-OG1 3.06Å
141	P	39.2	Very low	48.7	Very low	74 Å²	74	66 Å²	66	48%	0.481	35%	0.349	S	S	.	.			trans	-61.6	89.7	159.8	26.1	-29.3	0	0	0	106	F139 D143	F139-P141 WeakPolarHBondContact O-CD 3.25Å; P141-D143 PolarHBondContact O-N 3.38Å
142	T	49.7	Very low	49.1	Very low	37 Å²	37	70.8 Å²	70.8	23%	0.227	38%	0.379	C	S	.	.			trans	-81.9	51.7	176.3	-36.6	0	0	0	0	106.8	I140 L144 V168 L172	I140-T142 PolarHBondContact O-N 2.98Å; I140-T142 PolarHBondContact O-OG1 2.83Å; I140-T142 VanDerWaalsContact O-OG1 3.06Å; T142-L144 PolarHBondContact O-N 3.27Å; T142-V168 HydrophobicContact CG2-CG1 4.32Å; T142-L172 HydrophobicContact CG2-CD1 4.31Å; T142-L172 HydrophobicContact CG2-CD2 4.32Å
143	D	46.8	Very low	49.1	Very low	90 Å²	90	73.2 Å²	73.2	48%	0.481	39%	0.389	S	S	.	.			trans	-75.2	113	175.9	-73.9	-36.9	0	0	0	106.1	P141 D145 Q146 V147	P141-D143 PolarHBondContact O-N 3.38Å; D143-D145 PolarHBondContact O-N 3.08Å; D143-Q146 HydrophobicContact CB-CB 4.49Å; D143-Q146 HydrophobicContact CB-CG 4.23Å; D143-Q146 WeakPolarHBondContact O-CA 3.41Å; D143-Q146 WeakPolarHBondContact O-CB 3.32Å; D143-Q146 PolarHBondContact O-N 3.46Å; D143-V147 PolarHBondContact O-N 3.28Å
144	L	47.9	Very low	49.2	Very low	35 Å²	35	70 Å²	70	18%	0.183	37%	0.366	C	S	.	.	H	α-helix	trans	-46.8	-31.8	171.2	-83.8	161.7	0	0	0	112.2	T142 V147 R148 K183 V184	T142-L144 PolarHBondContact O-N 3.27Å; L144-V147 PolarHBondContact O-N 2.79Å; L144-R148 WeakPolarHBondContact O-CB 3.33Å; L144-R148 PolarHBondContact O-N 2.97Å; L144-K183 HydrophobicContact CD1-CB 3.61Å; L144-V184 HydrophobicContact CD1-CG2 4.11Å; L144-V184 HydrophobicContact CD2-CB 4.01Å; L144-V184 HydrophobicContact CD2-CG1 4.45Å; L144-V184 HydrophobicContact CD2-CG2 3.44Å; L144-V184 VanDerWaalsContact CD2-CG2 3.44Å; L144-V184 HydrophobicContact CG-CG2 3.84Å
145	D	47.2	Very low	48.9	Very low	112 Å²	112	76.5 Å²	76.5	60%	0.599	40%	0.4	S	S	*	.	H	α-helix	trans	-64.9	-36.1	173.7	-74	-77.4	0	0	0	114	D143 K149	D143-D145 PolarHBondContact O-N 3.08Å; D145-K149 WeakPolarHBondContact O-CB 3.03Å; D145-K149 VanDerWaalsContact O-CG 3.25Å; D145-K149 WeakPolarHBondContact O-CG 3.49Å; D145-K149 PolarHBondContact O-N 3.12Å
146	Q	53.5	Low	49.1	Very low	71 Å²	71	73.5 Å²	73.5	33%	0.332	38%	0.384	S	S	.	.	H	α-helix	trans	-72.9	-42	174.5	-71.7	-171.3	-20.1	0	0	111	D143 R148 K149 W150	D143-Q146 HydrophobicContact CB-CB 4.49Å; D143-Q146 HydrophobicContact CB-CG 4.23Å; D143-Q146 WeakPolarHBondContact O-CA 3.41Å; D143-Q146 WeakPolarHBondContact O-CB 3.32Å; D143-Q146 PolarHBondContact O-N 3.46Å; Q146-R148 VanDerWaalsContact C-N 3.29Å; Q146-R148 PolarHBondContact O-N 2.99Å; Q146-K149 PolarHBondContact O-N 3.48Å; Q146-W150 HydrophobicContact CB-CH2 4.15Å; Q146-W150 HydrophobicContact CB-CZ2 3.97Å; Q146-W150 WeakPolarHBondContact O-CB 3.45Å; Q146-W150 VanDerWaalsContact O-CD2 3.29Å; Q146-W150 PolarHBondContact O-N 3.1Å
147	V	55.1	Low	49.3	Very low	11 Å²	11	77.7 Å²	77.7	7%	0.067	40%	0.401	C	S	.	.	H	α-helix	trans	-61.9	-40.9	174.7	179.5	0	0	0	0	110.6	F124 D143 L144 W150 I151 L165	F124-V147 HydrophobicContact CZ-CG2 4.47Å; D143-V147 PolarHBondContact O-N 3.28Å; L144-V147 PolarHBondContact O-N 2.79Å; V147-W150 HydrophobicContact CG2-CE3 4.49Å; V147-W150 PolarHBondContact O-N 2.8Å; V147-I151 HydrophobicContact CG1-CD1 3.84Å; V147-I151 HydrophobicContact CG1-CG1 4.49Å; V147-I151 WeakPolarHBondContact O-CB 3.49Å; V147-I151 VanDerWaalsContact O-CD1 3.29Å; V147-I151 WeakPolarHBondContact O-CD1 3.35Å; V147-I151 WeakPolarHBondContact O-CG1 3.45Å; V147-I151 PolarHBondContact O-N 3.28Å; V147-L165 HydrophobicContact CG1-CD2 3.98Å
148	R	51.4	Low	49.7	Very low	128 Å²	128	80.2 Å²	80.2	48%	0.483	42%	0.417	S	S	.	.	H	α-helix	trans	-63.8	-42.5	175.2	-178.2	179.4	-67.2	-90.8	5.3	112.3	L144 Q146 I151 V152 E187	L144-R148 WeakPolarHBondContact O-CB 3.33Å; L144-R148 PolarHBondContact O-N 2.97Å; Q146-R148 VanDerWaalsContact C-N 3.29Å; Q146-R148 PolarHBondContact O-N 2.99Å; R148-I151 PolarHBondContact O-N 3.34Å; R148-V152 WeakPolarHBondContact O-CG2 3.49Å; R148-V152 PolarHBondContact O-N 3.33Å; R148-E187 IonicContact CZ-OE1 3.09Å; R148-E187 IonicContact CZ-OE2 3.28Å; R148-E187 IonicContact NE-OE1 3.63Å; R148-E187 PolarHBondContact NE-OE1 3.1Å; R148-E187 IonicContact NE-OE2 2.8Å; R148-E187 IonicContact NH1-OE1 3.38Å; R148-E187 IonicContact NH2-OE1 2.71Å; R148-E187 PolarHBondContact NH2-OE1 3.27Å; R148-E187 IonicContact NH2-OE2 3.74Å; R148-E187 PolarHBondContact NH2-OE2 3.22Å
149	K	56.2	Low	50.4	Low	138 Å²	138	79.6 Å²	79.6	60%	0.6	40%	0.402	S	S	*	.	H	α-helix	trans	-63	-48.8	174.5	-76.4	173.9	-178.4	-178.9	0	111	D145 Q146 I151 V152 D153	D145-K149 WeakPolarHBondContact O-CB 3.03Å; D145-K149 VanDerWaalsContact O-CG 3.25Å; D145-K149 WeakPolarHBondContact O-CG 3.49Å; D145-K149 PolarHBondContact O-N 3.12Å; Q146-K149 PolarHBondContact O-N 3.48Å; K149-I151 VanDerWaalsContact C-N 3.28Å; K149-I151 PolarHBondContact O-N 3.29Å; K149-V152 PolarHBondContact O-N 3.45Å; K149-D153 WeakPolarHBondContact O-CB 3.32Å; K149-D153 PolarHBondContact O-N 3.22Å; K149-D153 VanDerWaalsContact O-OD2 3.1Å
150	W	56.2	Low	51.1	Low	39 Å²	39	76 Å²	76	15%	0.148	39%	0.386	C	S	.	.	H	α-helix	trans	-60.8	-34	176.6	-62.5	-21.9	0	0	0	113.4	F110 F124 Q146 V147 V152 D153 W154	F110-W150 AromaticContact CE1-CH2 3.6Å; F110-W150 HydrophobicContact CE1-CH2 3.6Å; F110-W150 AromaticContact CE1-CZ2 3.4Å; F110-W150 HydrophobicContact CE1-CZ2 3.4Å; F110-W150 HydrophobicContact CE1-CZ3 4.41Å; F110-W150 HydrophobicContact CE2-CH2 4.45Å; F110-W150 HydrophobicContact CE2-CZ3 4.5Å; F110-W150 HydrophobicContact CZ-CD2 4.04Å; F110-W150 AromaticContact CZ-CE2 3.64Å; F110-W150 HydrophobicContact CZ-CE3 4.07Å; F110-W150 AromaticContact CZ-CH2 3.4Å; F110-W150 HydrophobicContact CZ-CH2 3.4Å; F110-W150 AromaticContact CZ-CZ2 3.34Å; F110-W150 HydrophobicContact CZ-CZ2 3.34Å; F110-W150 AromaticContact CZ-CZ3 3.76Å; F110-W150 HydrophobicContact CZ-CZ3 3.76Å; F124-W150 HydrophobicContact CD2-CZ3 4.31Å; F124-W150 AromaticContact CE2-CZ3 3.96Å; F124-W150 HydrophobicContact CE2-CZ3 3.96Å; F124-W150 HydrophobicContact CZ-CZ3 4.35Å; Q146-W150 HydrophobicContact CB-CH2 4.15Å; Q146-W150 HydrophobicContact CB-CZ2 3.97Å; Q146-W150 WeakPolarHBondContact O-CB 3.45Å; Q146-W150 VanDerWaalsContact O-CD2 3.29Å; Q146-W150 PolarHBondContact O-N 3.1Å; V147-W150 HydrophobicContact CG2-CE3 4.49Å; V147-W150 PolarHBondContact O-N 2.8Å; W150-V152 VanDerWaalsContact C-N 3.34Å; W150-D153 PolarHBondContact O-N 3.33Å; W150-W154 HydrophobicContact CB-CD2 4.09Å; W150-W154 HydrophobicContact CB-CE3 4.18Å; W150-W154 HydrophobicContact CB-CH2 3.82Å; W150-W154 HydrophobicContact CB-CZ2 3.68Å; W150-W154 HydrophobicContact CB-CZ3 4.08Å; W150-W154 HydrophobicContact CD2-CH2 4.21Å; W150-W154 HydrophobicContact CD2-CZ2 4.17Å; W150-W154 HydrophobicContact CE3-CH2 4.16Å; W150-W154 HydrophobicContact CG-CH2 4.08Å; W150-W154 AromaticContact CG-CZ2 3.76Å; W150-W154 HydrophobicContact CG-CZ2 3.76Å; W150-W154 WeakPolarHBondContact O-CB 3.43Å; W150-W154 VanDerWaalsContact O-CD2 3.29Å; W150-W154 PolarHBondContact O-N 2.81Å
151	I	54.3	Low	51.7	Low	43 Å²	43	76.7 Å²	76.7	22%	0.221	39%	0.387	C	S	.	.	H	α-helix	trans	-64.6	-39.5	174.1	-73.4	158.4	0	0	0	111.7	V147 R148 K149 N155 K161	V147-I151 HydrophobicContact CG1-CD1 3.84Å; V147-I151 HydrophobicContact CG1-CG1 4.49Å; V147-I151 WeakPolarHBondContact O-CB 3.49Å; V147-I151 VanDerWaalsContact O-CD1 3.29Å; V147-I151 WeakPolarHBondContact O-CD1 3.35Å; V147-I151 WeakPolarHBondContact O-CG1 3.45Å; V147-I151 PolarHBondContact O-N 3.28Å; R148-I151 PolarHBondContact O-N 3.34Å; K149-I151 VanDerWaalsContact C-N 3.28Å; K149-I151 PolarHBondContact O-N 3.29Å; I151-N155 PolarHBondContact O-N 3.3Å; I151-K161 HydrophobicContact CD1-CD 4.16Å; I151-K161 HydrophobicContact CD1-CG 4.34Å; I151-K161 HydrophobicContact CG1-CD 4.23Å; I151-K161 HydrophobicContact CG1-CG 4.4Å; I151-K161 HydrophobicContact CG2-CD 3.88Å
152	V	57.9	Low	52.6	Low	103 Å²	103	73.1 Å²	73.1	62%	0.624	37%	0.365	S	S	*	.	H	α-helix	trans	-74.2	-39.7	178.4	174.7	0	0	0	0	110.7	R148 K149 W150	R148-V152 WeakPolarHBondContact O-CG2 3.49Å; R148-V152 PolarHBondContact O-N 3.33Å; K149-V152 PolarHBondContact O-N 3.45Å; W150-V152 VanDerWaalsContact C-N 3.34Å
153	D	51.9	Low	53.1	Low	73 Å²	73	74 Å²	74	39%	0.39	37%	0.37	S	S	.	.	H	α-helix	trans	-70.5	-32.2	-179.8	-60.9	-27.5	0	0	0	111.8	N116 K149 W150	N116-D153 PolarHBondContact OD1-O 3.31Å; K149-D153 WeakPolarHBondContact O-CB 3.32Å; K149-D153 PolarHBondContact O-N 3.22Å; K149-D153 VanDerWaalsContact O-OD2 3.1Å; W150-D153 PolarHBondContact O-N 3.33Å
154	W	53.1	Low	53.7	Low	23 Å²	23	70.1 Å²	70.1	9%	0.087	35%	0.349	C	S	.	.	H	α-helix	trans	-92.1	-19	-176.4	-63.2	-14.3	0	0	0	114.9	F110 R120 W150 L156	F110-W154 HydrophobicContact CE2-CH2 4.38Å; F110-W154 HydrophobicContact CE2-CZ2 4.43Å; R120-W154 HydrophobicContact CB-CD2 4.49Å; R120-W154 HydrophobicContact CB-CH2 3.66Å; R120-W154 HydrophobicContact CB-CZ2 3.25Å; R120-W154 HydrophobicContact CB-CZ3 4.41Å; R120-W154 HydrophobicContact CG-CZ2 3.96Å; W150-W154 HydrophobicContact CB-CD2 4.09Å; W150-W154 HydrophobicContact CB-CE3 4.18Å; W150-W154 HydrophobicContact CB-CH2 3.82Å; W150-W154 HydrophobicContact CB-CZ2 3.68Å; W150-W154 HydrophobicContact CB-CZ3 4.08Å; W150-W154 HydrophobicContact CD2-CH2 4.21Å; W150-W154 HydrophobicContact CD2-CZ2 4.17Å; W150-W154 HydrophobicContact CE3-CH2 4.16Å; W150-W154 HydrophobicContact CG-CH2 4.08Å; W150-W154 AromaticContact CG-CZ2 3.76Å; W150-W154 HydrophobicContact CG-CZ2 3.76Å; W150-W154 WeakPolarHBondContact O-CB 3.43Å; W150-W154 VanDerWaalsContact O-CD2 3.29Å; W150-W154 PolarHBondContact O-N 2.81Å; W154-L156 HydrophobicContact CB-CD1 3.73Å; W154-L156 WeakPolarHBondContact O-CD1 3.45Å; W154-L156 PolarHBondContact O-N 3Å
155	N	40.8	Very low	54.4	Low	156 Å²	156	68.8 Å²	68.8	83%	0.834	34%	0.342	S	S	*	.			trans	46.8	33.8	177.8	-121.4	0.1	0	0	0	114.3	I151	I151-N155 PolarHBondContact O-N 3.3Å
156	L	52.1	Low	55.2	Low	46 Å²	46	66.2 Å²	66.2	24%	0.241	32%	0.324	C	S	.	.			trans	-88.9	147	-172.2	-108.4	112.1	0	0	0	112.7	P118 Y121 W154 T158 K160	P118-L156 HydrophobicContact CB-CD1 3.92Å; P118-L156 HydrophobicContact CB-CD2 4.19Å; Y121-L156 HydrophobicContact CG-CD2 4.4Å; W154-L156 HydrophobicContact CB-CD1 3.73Å; W154-L156 WeakPolarHBondContact O-CD1 3.45Å; W154-L156 PolarHBondContact O-N 3Å; L156-T158 PolarHBondContact O-N 3.28Å; L156-K160 HydrophobicContact CD2-CB 4.41Å; L156-K160 HydrophobicContact CD2-CD 3.82Å
157	N	49.6	Very low	55.5	Low	121 Å²	121	64.3 Å²	64.3	65%	0.647	32%	0.316	S	S	*	.			trans	-39.3	130.4	178.8	-87.8	-1	0	0	0	113.6	E159 K160 K161	N157-E159 PolarHBondContact O-N 3.42Å; N157-K160 PolarHBondContact O-N 3.44Å; N157-K161 PolarHBondContact O-N 3.25Å; N157-K161 VanDerWaalsContact O-N 3.15Å
158	T	55.4	Low	55.8	Low	62 Å²	62	64 Å²	64	38%	0.38	31%	0.314	S	S	.	.	H	α-helix	trans	-50.6	-31.2	-177.8	-33.1	0	0	0	0	113	L156 K161 H162	L156-T158 PolarHBondContact O-N 3.28Å; T158-K161 WeakPolarHBondContact O-CB 3.18Å; T158-H162 PolarHBondContact O-CD2 3.47Å; T158-H162 PolarHBondContact O-N 3.47Å; T158-H162 PolarHBondContact O-ND1 3.05Å; T158-H162 VanDerWaalsContact O-ND1 3.13Å
159	E	54.7	Low	56.3	Low	103 Å²	103	59 Å²	59	48%	0.481	30%	0.295	S	S	.	.	H	α-helix	trans	-73.2	-38.8	179	-54.6	-164.6	135.9	0	0	114.5	N157 H162 T163 N196	N157-E159 PolarHBondContact O-N 3.42Å; E159-H162 PolarHBondContact O-N 3.12Å; E159-T163 PolarHBondContact O-N 3.22Å; E159-T163 PolarHBondContact O-OG1 3.41Å; E159-N196 PolarHBondContact OE1-ND2 2.9Å
160	K	55.4	Low	56.4	Low	103 Å²	103	56.1 Å²	56.1	45%	0.448	28%	0.284	S	S	.	.	H	α-helix	trans	-66.8	-45.6	172.8	-79.3	-173.8	177.7	-174.9	0	108.4	Y121 L156 N157 H162 T163 L164	Y121-K160 HydrophobicContact CD1-CD 4.39Å; Y121-K160 HydrophobicContact CD2-CB 4.35Å; Y121-K160 HydrophobicContact CE1-CB 4.04Å; Y121-K160 HydrophobicContact CE1-CD 4.06Å; Y121-K160 HydrophobicContact CE1-CG 4.08Å; Y121-K160 HydrophobicContact CE2-CB 3.63Å; Y121-K160 WeakPolarHBondContact CE2-O 3.39Å; Y121-K160 VanDerWaalsContact CZ-CB 3.49Å; Y121-K160 WeakPolarHBondContact OH-CA 3.39Å; Y121-K160 PolarHBondContact OH-O 2.76Å; L156-K160 HydrophobicContact CD2-CB 4.41Å; L156-K160 HydrophobicContact CD2-CD 3.82Å; N157-K160 PolarHBondContact O-N 3.44Å; K160-H162 VanDerWaalsContact C-N 3.3Å; K160-H162 PolarHBondContact O-N 3.48Å; K160-T163 PolarHBondContact O-N 3.42Å; K160-T163 VanDerWaalsContact O-N 3.07Å; K160-L164 PolarHBondContact O-N 3.28Å
161	K	57	Low	56.4	Low	42 Å²	42	54.5 Å²	54.5	18%	0.183	28%	0.279	C	S	.	.	H	α-helix	trans	-51.9	-45.3	171.2	174.7	-179.7	168.1	-178	0	112.5	I151 N157 T158 L165 S191	I151-K161 HydrophobicContact CD1-CD 4.16Å; I151-K161 HydrophobicContact CD1-CG 4.34Å; I151-K161 HydrophobicContact CG1-CD 4.23Å; I151-K161 HydrophobicContact CG1-CG 4.4Å; I151-K161 HydrophobicContact CG2-CD 3.88Å; N157-K161 PolarHBondContact O-N 3.25Å; N157-K161 VanDerWaalsContact O-N 3.15Å; T158-K161 WeakPolarHBondContact O-CB 3.18Å; K161-L165 HydrophobicContact CD-CD1 4.47Å; K161-L165 HydrophobicContact CG-CD1 3.69Å; K161-L165 HydrophobicContact CG-CG 4.47Å; K161-L165 VanDerWaalsContact O-CB 3.28Å; K161-L165 WeakPolarHBondContact O-CB 3.35Å; K161-L165 WeakPolarHBondContact O-CD1 3.43Å; K161-L165 VanDerWaalsContact O-CG 3.24Å; K161-L165 WeakPolarHBondContact O-CG 3.14Å; K161-L165 PolarHBondContact O-N 3.37Å; K161-S191 WeakPolarHBondContact CE-OG 3.48Å; K161-S191 PolarHBondContact NZ-OG 2.99Å
162	H	58.2	Low	56.5	Low	0 Å²	0	52.6 Å²	52.6	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-65	-42.2	176.8	-63.7	154.8	0	0	0	112.8	T158 E159 K160 L165 R166 Y192	T158-H162 PolarHBondContact O-CD2 3.47Å; T158-H162 PolarHBondContact O-N 3.47Å; T158-H162 PolarHBondContact O-ND1 3.05Å; T158-H162 VanDerWaalsContact O-ND1 3.13Å; E159-H162 PolarHBondContact O-N 3.12Å; K160-H162 VanDerWaalsContact C-N 3.3Å; K160-H162 PolarHBondContact O-N 3.48Å; H162-L165 PolarHBondContact O-N 3.23Å; H162-R166 WeakPolarHBondContact O-CB 3.41Å; H162-R166 WeakPolarHBondContact O-CG 3.49Å; H162-R166 PolarHBondContact O-N 2.98Å; H162-Y192 HydrophobicContact CB-CE1 4.47Å; H162-Y192 AromaticContact CE1-CD1 3.44Å; H162-Y192 VanDerWaalsContact CE1-CD1 3.44Å; H162-Y192 WeakPolarHBondContact CE1-CD1 3.36Å; H162-Y192 AromaticContact CE1-CE1 3.58Å; H162-Y192 AromaticContact CG-CE1 3.78Å; H162-Y192 AromaticContact CG-CZ 3.96Å; H162-Y192 AromaticContact ND1-CD1 3.83Å; H162-Y192 AromaticContact ND1-CE1 3.48Å; H162-Y192 WeakPolarHBondContact ND1-CE1 3.45Å; H162-Y192 AromaticContact NE2-CD1 3.83Å; H162-Y192 AromaticContact NE2-CE1 3.94Å; H162-Y192 AromaticContact NE2-CG 4Å
163	T	61	Low	56.5	Low	56 Å²	56	48.9 Å²	48.9	34%	0.344	25%	0.247	S	C	.	.	H	α-helix	trans	-65.1	-42.1	178.7	-55.5	0	0	0	0	111.5	E159 K160 R166 L167	E159-T163 PolarHBondContact O-N 3.22Å; E159-T163 PolarHBondContact O-OG1 3.41Å; K160-T163 PolarHBondContact O-N 3.42Å; K160-T163 VanDerWaalsContact O-N 3.07Å; T163-R166 WeakPolarHBondContact O-CB 3.23Å; T163-R166 PolarHBondContact O-N 3.36Å; T163-L167 WeakPolarHBondContact O-CG 3.5Å; T163-L167 PolarHBondContact O-N 3.32Å
164	L	59.6	Low	56.6	Low	8 Å²	8	49.6 Å²	49.6	4%	0.042	25%	0.25	C	S	.	.	H	α-helix	trans	-65.6	-47.5	176.4	172.5	68.6	0	0	0	112.1	Y121 F124 C125 K160 R166 L167 V168	Y121-L164 HydrophobicContact CD2-CB 4.12Å; Y121-L164 HydrophobicContact CD2-CD2 3.96Å; Y121-L164 HydrophobicContact CE2-CB 3.41Å; Y121-L164 VanDerWaalsContact CE2-CB 3.41Å; Y121-L164 HydrophobicContact CE2-CD2 4.1Å; Y121-L164 HydrophobicContact CE2-CG 4.26Å; F124-L164 HydrophobicContact CD1-CD1 3.16Å; F124-L164 HydrophobicContact CD1-CD2 3.49Å; F124-L164 VanDerWaalsContact CD1-CD2 3.49Å; F124-L164 HydrophobicContact CD1-CG 3.71Å; F124-L164 HydrophobicContact CE1-CD1 3.58Å; F124-L164 HydrophobicContact CE1-CD2 3.78Å; F124-L164 HydrophobicContact CE1-CG 3.85Å; F124-L164 HydrophobicContact CG-CD1 4.18Å; C125-L164 HydrophobicContact CB-CD1 4.37Å; C125-L164 WeakPolarHBondContact SG-CD1 3.1Å; K160-L164 PolarHBondContact O-N 3.28Å; L164-R166 VanDerWaalsContact C-N 3.25Å; L164-R166 PolarHBondContact O-N 2.95Å; L164-L167 CarbonylContact O-C 3.6Å; L164-L167 WeakPolarHBondContact O-CB 3.46Å; L164-L167 PolarHBondContact O-N 3.27Å; L164-L167 VanDerWaalsContact O-N 3.07Å; L164-V168 HydrophobicContact CD1-CG2 4.33Å; L164-V168 HydrophobicContact CG-CG2 4.38Å; L164-V168 VanDerWaalsContact O-CG2 3.3Å; L164-V168 WeakPolarHBondContact O-CG2 3.49Å; L164-V168 PolarHBondContact O-N 3.43Å
165	L	61.6	Low	56.4	Low	6 Å²	6	49.6 Å²	49.6	3%	0.031	25%	0.254	C	S	.	.	H	α-helix	trans	-65.6	-31.3	179.5	-73.9	168.5	0	0	0	111.4	V147 K161 H162 V168 Y169 V184 L188	V147-L165 HydrophobicContact CG1-CD2 3.98Å; K161-L165 HydrophobicContact CD-CD1 4.47Å; K161-L165 HydrophobicContact CG-CD1 3.69Å; K161-L165 HydrophobicContact CG-CG 4.47Å; K161-L165 VanDerWaalsContact O-CB 3.28Å; K161-L165 WeakPolarHBondContact O-CB 3.35Å; K161-L165 WeakPolarHBondContact O-CD1 3.43Å; K161-L165 VanDerWaalsContact O-CG 3.24Å; K161-L165 WeakPolarHBondContact O-CG 3.14Å; K161-L165 PolarHBondContact O-N 3.37Å; H162-L165 PolarHBondContact O-N 3.23Å; L165-V168 PolarHBondContact O-N 3.22Å; L165-Y169 WeakPolarHBondContact O-CB 3.47Å; L165-Y169 PolarHBondContact O-N 3.25Å; L165-V184 HydrophobicContact CD2-CG1 4.06Å; L165-L188 HydrophobicContact CB-CD1 3.71Å; L165-L188 HydrophobicContact CB-CD2 3.11Å; L165-L188 HydrophobicContact CB-CG 3.37Å; L165-L188 HydrophobicContact CD1-CD2 3.55Å; L165-L188 HydrophobicContact CD1-CG 3.83Å; L165-L188 HydrophobicContact CD2-CG 4.46Å; L165-L188 HydrophobicContact CG-CD2 3.94Å; L165-L188 HydrophobicContact CG-CG 4.08Å
166	R	63.6	Low	56.9	Low	59 Å²	59	50.7 Å²	50.7	22%	0.223	25%	0.251	C	S	.	.	H	α-helix	trans	-61.5	-45.6	167.5	-80.1	-175.2	-141.5	137.4	6.1	112	H162 T163 L164 V168 Y169 E170 Q199 D203	H162-R166 WeakPolarHBondContact O-CB 3.41Å; H162-R166 WeakPolarHBondContact O-CG 3.49Å; H162-R166 PolarHBondContact O-N 2.98Å; T163-R166 WeakPolarHBondContact O-CB 3.23Å; T163-R166 PolarHBondContact O-N 3.36Å; L164-R166 VanDerWaalsContact C-N 3.25Å; L164-R166 PolarHBondContact O-N 2.95Å; R166-V168 VanDerWaalsContact C-N 3.32Å; R166-V168 PolarHBondContact O-N 2.83Å; R166-Y169 WeakPolarHBondContact O-CB 3.46Å; R166-Y169 PolarHBondContact O-N 2.92Å; R166-E170 WeakPolarHBondContact O-CG 3.44Å; R166-E170 PolarHBondContact O-N 3.34Å; R166-Q199 VanDerWaalsContact NH2-OE1 3.16Å; R166-D203 WeakPolarHBondContact CD-OD1 3.18Å; R166-D203 IonicContact CZ-OD2 3.88Å; R166-D203 IonicContact NE-OD1 2.7Å; R166-D203 PolarHBondContact NE-OD1 3.26Å; R166-D203 IonicContact NE-OD2 3.72Å; R166-D203 PolarHBondContact NE-OD2 2.85Å; R166-D203 IonicContact NH2-OD2 2.69Å; R166-D203 PolarHBondContact NH2-OD2 2.82Å
167	L	61	Low	57	Low	31 Å²	31	53.2 Å²	53.2	16%	0.162	26%	0.26	C	S	.	.	H	α-helix	trans	-63	-41.9	177.3	-70.7	169.4	0	0	0	110.9	C125 V128 K129 T163 L164 Y169 E170 A171	C125-L167 HydrophobicContact CB-CD1 4.05Å; V128-L167 HydrophobicContact CG1-CB 3.75Å; V128-L167 WeakPolarHBondContact CG1-O 3.25Å; K129-L167 HydrophobicContact CG-CD2 4.27Å; T163-L167 WeakPolarHBondContact O-CG 3.5Å; T163-L167 PolarHBondContact O-N 3.32Å; L164-L167 CarbonylContact O-C 3.6Å; L164-L167 WeakPolarHBondContact O-CB 3.46Å; L164-L167 PolarHBondContact O-N 3.27Å; L164-L167 VanDerWaalsContact O-N 3.07Å; L167-Y169 VanDerWaalsContact C-N 3.29Å; L167-Y169 PolarHBondContact O-N 2.99Å; L167-E170 PolarHBondContact O-N 2.78Å; L167-A171 WeakPolarHBondContact O-CB 3.46Å; L167-A171 PolarHBondContact O-N 3.27Å
168	V	60.9	Low	57.1	Low	5 Å²	5	48.6 Å²	48.6	3%	0.03	24%	0.238	C	C	.	.	H	α-helix	trans	-62.9	-40.9	176.7	172.3	0	0	0	0	109.8	F124 V128 T142 L164 L165 R166 A171 L172 V184	F124-V168 HydrophobicContact CE1-CG2 3.6Å; F124-V168 HydrophobicContact CZ-CG2 3.89Å; V128-V168 HydrophobicContact CG1-CG2 4.18Å; V128-V168 HydrophobicContact CG2-CG2 3.65Å; T142-V168 HydrophobicContact CG2-CG1 4.32Å; L164-V168 HydrophobicContact CD1-CG2 4.33Å; L164-V168 HydrophobicContact CG-CG2 4.38Å; L164-V168 VanDerWaalsContact O-CG2 3.3Å; L164-V168 WeakPolarHBondContact O-CG2 3.49Å; L164-V168 PolarHBondContact O-N 3.43Å; L165-V168 PolarHBondContact O-N 3.22Å; R166-V168 VanDerWaalsContact C-N 3.32Å; R166-V168 PolarHBondContact O-N 2.83Å; V168-A171 PolarHBondContact O-N 3.46Å; V168-L172 HydrophobicContact CG1-CD1 3.72Å; V168-L172 HydrophobicContact CG1-CG 4.39Å; V168-L172 WeakPolarHBondContact O-CB 3.23Å; V168-L172 WeakPolarHBondContact O-CD1 3.29Å; V168-L172 WeakPolarHBondContact O-CG 3.39Å; V168-L172 PolarHBondContact O-N 2.93Å; V168-V184 HydrophobicContact CG1-CG1 4.23Å
169	Y	61	Low	56.9	Low	21 Å²	21	52 Å²	52	8%	0.082	25%	0.249	C	C	.	.	H	α-helix	trans	-62.4	-47.1	173.8	175.5	-104.1	0	0	0	112.3	L165 R166 L167 A171 L172 V173 A181 M185 R210	L165-Y169 WeakPolarHBondContact O-CB 3.47Å; L165-Y169 PolarHBondContact O-N 3.25Å; R166-Y169 WeakPolarHBondContact O-CB 3.46Å; R166-Y169 PolarHBondContact O-N 2.92Å; L167-Y169 VanDerWaalsContact C-N 3.29Å; L167-Y169 PolarHBondContact O-N 2.99Å; Y169-A171 PolarHBondContact O-N 3.03Å; Y169-L172 PolarHBondContact O-N 3.29Å; Y169-V173 HydrophobicContact CD1-CG2 4.06Å; Y169-V173 HydrophobicContact CD2-CG2 4.09Å; Y169-V173 HydrophobicContact CE1-CG2 3.72Å; Y169-V173 HydrophobicContact CE2-CG2 3.76Å; Y169-V173 HydrophobicContact CG-CG2 4.25Å; Y169-V173 WeakPolarHBondContact O-CB 3.14Å; Y169-V173 WeakPolarHBondContact O-CG2 3.31Å; Y169-V173 PolarHBondContact O-N 3.39Å; Y169-A181 HydrophobicContact CD2-CB 4.04Å; Y169-A181 HydrophobicContact CE2-CB 4.08Å; Y169-M185 HydrophobicContact CD1-CE 3.45Å; Y169-M185 VanDerWaalsContact CD1-CE 3.45Å; Y169-M185 HydrophobicContact CD2-CB 4.29Å; Y169-M185 HydrophobicContact CD2-CE 3.24Å; Y169-M185 HydrophobicContact CE1-CE 3.57Å; Y169-M185 HydrophobicContact CE2-CB 4.25Å; Y169-M185 HydrophobicContact CE2-CE 3.35Å; Y169-M185 HydrophobicContact CE2-CG 4.5Å; Y169-M185 HydrophobicContact CG-CE 3.25Å; Y169-M185 VanDerWaalsContact CZ-CE 3.5Å; Y169-R210 VanDerWaalsContact OH-CB 3.31Å; Y169-R210 WeakPolarHBondContact OH-CB 3.27Å; Y169-R210 VanDerWaalsContact OH-CG 3.25Å; Y169-R210 WeakPolarHBondContact OH-CG 3.33Å
170	E	59.6	Low	57	Low	78 Å²	78	48.8 Å²	48.8	36%	0.364	24%	0.24	S	C	.	.	H	α-helix	trans	-60.5	-44.1	177.3	-73.2	-179.1	168.7	0	0	111.3	R166 L167 L172 V173 D174 R206	R166-E170 WeakPolarHBondContact O-CG 3.44Å; R166-E170 PolarHBondContact O-N 3.34Å; L167-E170 PolarHBondContact O-N 2.78Å; E170-L172 PolarHBondContact O-N 3.11Å; E170-V173 WeakPolarHBondContact O-CB 3.31Å; E170-V173 PolarHBondContact O-N 3.43Å; E170-D174 PolarHBondContact O-N 2.9Å; E170-R206 IonicContact OE1-NH1 3.19Å; E170-R206 PolarHBondContact OE1-NH1 3.38Å
171	A	56.3	Low	56.9	Low	5 Å²	5	44 Å²	44	4%	0.041	22%	0.22	C	C	.	.	H	α-helix	trans	-63.1	-38.7	175.2	0	0	0	0	0	113.1	V128 A132 I137 L167 V168 Y169 C175	V128-A171 HydrophobicContact CG1-CB 3.69Å; A132-A171 HydrophobicContact CB-CB 3.85Å; I137-A171 WeakPolarHBondContact CD1-O 3.38Å; L167-A171 WeakPolarHBondContact O-CB 3.46Å; L167-A171 PolarHBondContact O-N 3.27Å; V168-A171 PolarHBondContact O-N 3.46Å; Y169-A171 PolarHBondContact O-N 3.03Å; A171-C175 PolarHBondContact O-N 2.72Å; A171-C175 PolarHBondContact O-SG 3.47Å; A171-C175 VanDerWaalsContact O-SG 3.33Å
172	L	54.9	Low	56.7	Low	3 Å²	3	43.9 Å²	43.9	2%	0.016	23%	0.227	C	C	.	.	H	α-helix	trans	-71.2	-32.4	176.1	-75.3	166.4	0	0	0	112.7	I137 T142 V168 Y169 E170 C175 K176 K177 A181 V184	I137-L172 HydrophobicContact CD1-CD2 4.38Å; T142-L172 HydrophobicContact CG2-CD1 4.31Å; T142-L172 HydrophobicContact CG2-CD2 4.32Å; V168-L172 HydrophobicContact CG1-CD1 3.72Å; V168-L172 HydrophobicContact CG1-CG 4.39Å; V168-L172 WeakPolarHBondContact O-CB 3.23Å; V168-L172 WeakPolarHBondContact O-CD1 3.29Å; V168-L172 WeakPolarHBondContact O-CG 3.39Å; V168-L172 PolarHBondContact O-N 2.93Å; Y169-L172 PolarHBondContact O-N 3.29Å; E170-L172 PolarHBondContact O-N 3.11Å; L172-C175 PolarHBondContact O-N 3.34Å; L172-K176 PolarHBondContact O-N 2.65Å; L172-K177 HydrophobicContact CD2-CB 4.41Å; L172-K177 PolarHBondContact O-N 2.94Å; L172-A181 HydrophobicContact CB-CB 3.91Å; L172-V184 HydrophobicContact CD1-CB 4.39Å; L172-V184 HydrophobicContact CD1-CG2 3.79Å
173	V	58.6	Low	56.8	Low	25 Å²	25	49 Å²	49	15%	0.152	25%	0.249	C	C	.	.	H	α-helix	trans	-67.8	-42	175.8	163.8	0	0	0	0	110.8	Y169 E170 C175 K176	Y169-V173 HydrophobicContact CD1-CG2 4.06Å; Y169-V173 HydrophobicContact CD2-CG2 4.09Å; Y169-V173 HydrophobicContact CE1-CG2 3.72Å; Y169-V173 HydrophobicContact CE2-CG2 3.76Å; Y169-V173 HydrophobicContact CG-CG2 4.25Å; Y169-V173 WeakPolarHBondContact O-CB 3.14Å; Y169-V173 WeakPolarHBondContact O-CG2 3.31Å; Y169-V173 PolarHBondContact O-N 3.39Å; E170-V173 WeakPolarHBondContact O-CB 3.31Å; E170-V173 PolarHBondContact O-N 3.43Å; V173-C175 VanDerWaalsContact C-N 3.26Å; V173-C175 PolarHBondContact O-N 2.96Å; V173-K176 PolarHBondContact O-N 3.19Å
174	D	55	Low	56.7	Low	88 Å²	88	46.6 Å²	46.6	47%	0.471	23%	0.234	S	C	.	.	H	α-helix	trans	-64.6	-34.3	175.7	-72.3	-18.4	0	0	0	111.4	N135 E170 K176	N135-D174 PolarHBondContact OD1-O 2.84Å; E170-D174 PolarHBondContact O-N 2.9Å; D174-K176 VanDerWaalsContact C-N 3.31Å; D174-K176 PolarHBondContact O-N 3.46Å
175	C	48.1	Very low	56.5	Low	24 Å²	24	47 Å²	47	16%	0.162	24%	0.236	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85	7.1	179	-68	0	0	0	0	115.2	N135 I137 A171 L172 V173 K177	N135-C175 PolarHBondContact OD1-SG 3.46Å; I137-C175 HydrophobicContact CD1-CB 3.58Å; I137-C175 WeakPolarHBondContact CD1-SG 3.45Å; I137-C175 HydrophobicContact CG1-CB 4.13Å; I137-C175 WeakPolarHBondContact CG1-SG 3.29Å; A171-C175 PolarHBondContact O-N 2.72Å; A171-C175 PolarHBondContact O-SG 3.47Å; A171-C175 VanDerWaalsContact O-SG 3.33Å; L172-C175 PolarHBondContact O-N 3.34Å; V173-C175 VanDerWaalsContact C-N 3.26Å; V173-C175 PolarHBondContact O-N 2.96Å; C175-K177 PolarHBondContact O-N 3.48Å
176	K	51.7	Low	56.4	Low	179 Å²	179	48.9 Å²	48.9	78%	0.778	25%	0.247	S	C	*	.	T	Hydrogen-bonded Turn	trans	56.2	15	177.7	-58.2	-178.5	-179.7	176.3	0	115.6	L172 V173 D174 S178	L172-K176 PolarHBondContact O-N 2.65Å; V173-K176 PolarHBondContact O-N 3.19Å; D174-K176 VanDerWaalsContact C-N 3.31Å; D174-K176 PolarHBondContact O-N 3.46Å; K176-S178 PolarHBondContact O-N 2.86Å
177	K	53.1	Low	56.2	Low	98 Å²	98	47.7 Å²	47.7	43%	0.426	24%	0.244	S	C	.	.			trans	-81.2	66.4	172.2	-71.7	-175.6	-180	176.6	0	110.1	I137 L172 C175 E179 A180 A181	I137-K177 PolarHBondContact O-NZ 2.92Å; L172-K177 HydrophobicContact CD2-CB 4.41Å; L172-K177 PolarHBondContact O-N 2.94Å; C175-K177 PolarHBondContact O-N 3.48Å; K177-E179 VanDerWaalsContact C-N 3.29Å; K177-E179 PolarHBondContact O-N 2.86Å; K177-A180 PolarHBondContact O-N 2.9Å; K177-A181 WeakPolarHBondContact O-CB 3.47Å; K177-A181 PolarHBondContact O-N 3.13Å
178	S	52.5	Low	56.1	Low	25 Å²	25	46.3 Å²	46.3	18%	0.175	24%	0.237	C	C	.	.	H	α-helix	trans	-56.9	-35.4	-173.7	176.2	0	0	0	0	113.6	K176 A182 D214	K176-S178 PolarHBondContact O-N 2.86Å; S178-A182 WeakPolarHBondContact O-CB 3.45Å; S178-A182 PolarHBondContact O-N 3.48Å; S178-D214 WeakPolarHBondContact CB-OD2 3.36Å; S178-D214 PolarHBondContact OG-OD2 3.47Å
179	E	51.8	Low	55.9	Low	133 Å²	133	46.2 Å²	46.2	62%	0.621	24%	0.236	S	C	*	.	H	α-helix	trans	-73.6	-40.7	-177.8	-161.2	-169.5	148.4	0	0	113.2	K177 A182 K183	K177-E179 VanDerWaalsContact C-N 3.29Å; K177-E179 PolarHBondContact O-N 2.86Å; E179-A182 PolarHBondContact O-N 3.4Å; E179-K183 WeakPolarHBondContact O-CG 3.2Å; E179-K183 PolarHBondContact O-N 2.89Å; E179-K183 VanDerWaalsContact O-N 3.11Å; E179-K183 WeakPolarHBondContact OE1-CE 3.32Å; E179-K183 IonicContact OE1-NZ 3.67Å; E179-K183 PolarHBondContact OE1-NZ 3.41Å
180	A	55.3	Low	55.8	Low	35 Å²	35	47.7 Å²	47.7	29%	0.289	26%	0.259	S	S	.	.	H	α-helix	trans	-70.1	-40.4	174.9	0	0	0	0	0	110.7	K177 A182 K183 V184	K177-A180 PolarHBondContact O-N 2.9Å; A180-A182 VanDerWaalsContact C-N 3.29Å; A180-A182 PolarHBondContact O-N 3.37Å; A180-K183 PolarHBondContact O-N 3.19Å; A180-V184 WeakPolarHBondContact O-CG2 3.08Å; A180-V184 PolarHBondContact O-N 3.38Å
181	A	53.7	Low	55.6	Low	3 Å²	3	45.2 Å²	45.2	3%	0.025	25%	0.25	C	C	.	.	H	α-helix	trans	-57.8	-42	172.8	0	0	0	0	0	111.8	Y169 L172 K177 M185	Y169-A181 HydrophobicContact CD2-CB 4.04Å; Y169-A181 HydrophobicContact CE2-CB 4.08Å; L172-A181 HydrophobicContact CB-CB 3.91Å; K177-A181 WeakPolarHBondContact O-CB 3.47Å; K177-A181 PolarHBondContact O-N 3.13Å; A181-M185 WeakPolarHBondContact O-CB 3.36Å; A181-M185 PolarHBondContact O-N 3.2Å
182	A	54.1	Low	55.6	Low	39 Å²	39	46.2 Å²	46.2	32%	0.322	25%	0.252	S	S	.	.	H	α-helix	trans	-65.8	-40.6	176.9	0	0	0	0	0	112.6	S178 E179 A180 M185 V186	S178-A182 WeakPolarHBondContact O-CB 3.45Å; S178-A182 PolarHBondContact O-N 3.48Å; E179-A182 PolarHBondContact O-N 3.4Å; A180-A182 VanDerWaalsContact C-N 3.29Å; A180-A182 PolarHBondContact O-N 3.37Å; A182-M185 WeakPolarHBondContact O-CB 3.43Å; A182-M185 PolarHBondContact O-N 3.49Å; A182-V186 WeakPolarHBondContact O-CG2 3.42Å; A182-V186 PolarHBondContact O-N 2.86Å
183	K	60.1	Low	55.3	Low	109 Å²	109	49.9 Å²	49.9	47%	0.474	28%	0.275	S	S	.	.	H	α-helix	trans	-68.2	-44.9	177.2	-70.4	173.6	-171.4	165.8	0	112.3	L144 E179 A180 M185 V186 E187	L144-K183 HydrophobicContact CD1-CB 3.61Å; E179-K183 WeakPolarHBondContact O-CG 3.2Å; E179-K183 PolarHBondContact O-N 2.89Å; E179-K183 VanDerWaalsContact O-N 3.11Å; E179-K183 WeakPolarHBondContact OE1-CE 3.32Å; E179-K183 IonicContact OE1-NZ 3.67Å; E179-K183 PolarHBondContact OE1-NZ 3.41Å; A180-K183 PolarHBondContact O-N 3.19Å; K183-M185 PolarHBondContact O-N 2.74Å; K183-V186 PolarHBondContact O-N 3.38Å; K183-E187 PolarHBondContact O-N 3.42Å; K183-E187 VanDerWaalsContact O-N 3.08Å
184	V	58.3	Low	54.7	Low	4 Å²	4	57.1 Å²	57.1	2%	0.024	31%	0.308	C	S	.	.	H	α-helix	trans	-58.1	-37.4	171.5	178.5	0	0	0	0	110.8	L144 L165 V168 L172 A180 E187 L188	L144-V184 HydrophobicContact CD1-CG2 4.11Å; L144-V184 HydrophobicContact CD2-CB 4.01Å; L144-V184 HydrophobicContact CD2-CG1 4.45Å; L144-V184 HydrophobicContact CD2-CG2 3.44Å; L144-V184 VanDerWaalsContact CD2-CG2 3.44Å; L144-V184 HydrophobicContact CG-CG2 3.84Å; L165-V184 HydrophobicContact CD2-CG1 4.06Å; V168-V184 HydrophobicContact CG1-CG1 4.23Å; L172-V184 HydrophobicContact CD1-CB 4.39Å; L172-V184 HydrophobicContact CD1-CG2 3.79Å; A180-V184 WeakPolarHBondContact O-CG2 3.08Å; A180-V184 PolarHBondContact O-N 3.38Å; V184-E187 PolarHBondContact O-N 3.02Å; V184-L188 HydrophobicContact CG1-CD1 4.44Å; V184-L188 VanDerWaalsContact O-CB 3.31Å; V184-L188 WeakPolarHBondContact O-CB 3.17Å; V184-L188 PolarHBondContact O-N 3.01Å
185	M	55.8	Low	54.1	Low	16 Å²	16	59.9 Å²	59.9	8%	0.079	32%	0.322	C	S	.	.	H	α-helix	trans	-70.7	-37.8	178.4	-172.9	55.5	73.8	0	0	113.7	Y169 A181 A182 K183 E187 L188 L189 C207	Y169-M185 HydrophobicContact CD1-CE 3.45Å; Y169-M185 VanDerWaalsContact CD1-CE 3.45Å; Y169-M185 HydrophobicContact CD2-CB 4.29Å; Y169-M185 HydrophobicContact CD2-CE 3.24Å; Y169-M185 HydrophobicContact CE1-CE 3.57Å; Y169-M185 HydrophobicContact CE2-CB 4.25Å; Y169-M185 HydrophobicContact CE2-CE 3.35Å; Y169-M185 HydrophobicContact CE2-CG 4.5Å; Y169-M185 HydrophobicContact CG-CE 3.25Å; Y169-M185 VanDerWaalsContact CZ-CE 3.5Å; A181-M185 WeakPolarHBondContact O-CB 3.36Å; A181-M185 PolarHBondContact O-N 3.2Å; A182-M185 WeakPolarHBondContact O-CB 3.43Å; A182-M185 PolarHBondContact O-N 3.49Å; K183-M185 PolarHBondContact O-N 2.74Å; M185-E187 VanDerWaalsContact C-N 3.32Å; M185-L188 HydrophobicContact CE-CD1 3.97Å; M185-L188 WeakPolarHBondContact O-CB 3.34Å; M185-L188 PolarHBondContact O-N 3.04Å; M185-L188 HydrophobicContact SD-CB 4.06Å; M185-L188 HydrophobicContact SD-CD1 3.73Å; M185-L189 HydrophobicContact CG-CD1 3.98Å; M185-L189 WeakPolarHBondContact O-CB 3.44Å; M185-L189 WeakPolarHBondContact O-CG 3.33Å; M185-L189 PolarHBondContact O-N 2.9Å; M185-L189 HydrophobicContact SD-CD1 4.25Å; M185-L189 HydrophobicContact SD-CG 4.27Å; M185-C207 WeakPolarHBondContact CE-SG 3.44Å; M185-C207 HydrophobicContact CG-CB 4.29Å; M185-C207 VanDerWaalsContact CG-SG 3.54Å; M185-C207 PolarHBondContact SD-SG 2.86Å
186	V	59.5	Low	54.3	Low	46 Å²	46	60 Å²	60	28%	0.279	32%	0.321	S	S	.	.	H	α-helix	trans	-66.4	-38.5	174.9	169.9	0	0	0	0	110.6	A182 K183 L189 G190 H222 L226	A182-V186 WeakPolarHBondContact O-CG2 3.42Å; A182-V186 PolarHBondContact O-N 2.86Å; K183-V186 PolarHBondContact O-N 3.38Å; V186-L189 PolarHBondContact O-N 3.04Å; V186-G190 PolarHBondContact O-N 2.84Å; V186-H222 HydrophobicContact CG2-CB 4.15Å; V186-L226 HydrophobicContact CG1-CD1 4.41Å
187	E	58.6	Low	54	Low	34 Å²	34	53.1 Å²	53.1	16%	0.159	30%	0.298	C	S	.	.	H	α-helix	trans	-70.2	-35.3	176.1	-173.5	163	167.1	0	0	112.8	R148 K183 V184 M185 S191	R148-E187 IonicContact CZ-OE1 3.09Å; R148-E187 IonicContact CZ-OE2 3.28Å; R148-E187 IonicContact NE-OE1 3.63Å; R148-E187 PolarHBondContact NE-OE1 3.1Å; R148-E187 IonicContact NE-OE2 2.8Å; R148-E187 IonicContact NH1-OE1 3.38Å; R148-E187 IonicContact NH2-OE1 2.71Å; R148-E187 PolarHBondContact NH2-OE1 3.27Å; R148-E187 IonicContact NH2-OE2 3.74Å; R148-E187 PolarHBondContact NH2-OE2 3.22Å; K183-E187 PolarHBondContact O-N 3.42Å; K183-E187 VanDerWaalsContact O-N 3.08Å; V184-E187 PolarHBondContact O-N 3.02Å; M185-E187 VanDerWaalsContact C-N 3.32Å; E187-S191 WeakPolarHBondContact O-CB 3.4Å; E187-S191 PolarHBondContact O-N 3.11Å; E187-S191 PolarHBondContact O-OG 3.26Å
188	L	59.6	Low	54	Low	2 Å²	2	52.5 Å²	52.5	1%	0.01	31%	0.306	C	S	.	.	H	α-helix	trans	-56	-59.1	167.1	-101.3	168.2	0	0	0	111.7	L165 V184 M185 G190 S191 Y192	L165-L188 HydrophobicContact CB-CD1 3.71Å; L165-L188 HydrophobicContact CB-CD2 3.11Å; L165-L188 HydrophobicContact CB-CG 3.37Å; L165-L188 HydrophobicContact CD1-CD2 3.55Å; L165-L188 HydrophobicContact CD1-CG 3.83Å; L165-L188 HydrophobicContact CD2-CG 4.46Å; L165-L188 HydrophobicContact CG-CD2 3.94Å; L165-L188 HydrophobicContact CG-CG 4.08Å; V184-L188 HydrophobicContact CG1-CD1 4.44Å; V184-L188 VanDerWaalsContact O-CB 3.31Å; V184-L188 WeakPolarHBondContact O-CB 3.17Å; V184-L188 PolarHBondContact O-N 3.01Å; M185-L188 HydrophobicContact CE-CD1 3.97Å; M185-L188 WeakPolarHBondContact O-CB 3.34Å; M185-L188 PolarHBondContact O-N 3.04Å; M185-L188 HydrophobicContact SD-CB 4.06Å; M185-L188 HydrophobicContact SD-CD1 3.73Å; L188-G190 VanDerWaalsContact C-N 3.26Å; L188-G190 PolarHBondContact O-N 3.04Å; L188-S191 WeakPolarHBondContact O-CA 3.4Å; L188-S191 WeakPolarHBondContact O-CB 3.34Å; L188-S191 PolarHBondContact O-N 3.17Å; L188-Y192 HydrophobicContact CD2-CE2 4.5Å; L188-Y192 WeakPolarHBondContact O-CD2 3.46Å; L188-Y192 WeakPolarHBondContact O-CE2 3.21Å; L188-Y192 PolarHBondContact O-N 2.86Å
189	L	57.4	Low	54.1	Low	3 Å²	3	55.2 Å²	55.2	2%	0.016	32%	0.316	C	S	.	.	H	α-helix	trans	-64	-32.4	-177.8	-75.7	164.9	0	0	0	111.9	M185 V186 S191 Y192 L223 L226	M185-L189 HydrophobicContact CG-CD1 3.98Å; M185-L189 WeakPolarHBondContact O-CB 3.44Å; M185-L189 WeakPolarHBondContact O-CG 3.33Å; M185-L189 PolarHBondContact O-N 2.9Å; M185-L189 HydrophobicContact SD-CD1 4.25Å; M185-L189 HydrophobicContact SD-CG 4.27Å; V186-L189 PolarHBondContact O-N 3.04Å; L189-S191 VanDerWaalsContact C-N 3.31Å; L189-Y192 HydrophobicContact CD2-CD2 4.44Å; L189-Y192 HydrophobicContact CD2-CE2 4.36Å; L189-L223 HydrophobicContact CD1-CD2 4.05Å; L189-L226 HydrophobicContact CB-CD1 3.67Å; L189-L226 HydrophobicContact CD1-CD1 4.09Å
190	G	57.8	Low	54.2	Low	53 Å²	53	49.1 Å²	49.1	55%	0.546	29%	0.288	S	S	.	.	H	α-helix	trans	-73.4	-17.9	172	0	0	0	0	0	114.5	V186 L188	V186-G190 PolarHBondContact O-N 2.84Å; L188-G190 VanDerWaalsContact C-N 3.26Å; L188-G190 PolarHBondContact O-N 3.04Å
191	S	56.2	Low	54.4	Low	25 Å²	25	52 Å²	52	18%	0.175	29%	0.291	C	S	.	.	H	α-helix	trans	-88.7	-9.2	177.6	-65.5	0	0	0	0	113.9	K161 E187 L188 L189 T193	K161-S191 WeakPolarHBondContact CE-OG 3.48Å; K161-S191 PolarHBondContact NZ-OG 2.99Å; E187-S191 WeakPolarHBondContact O-CB 3.4Å; E187-S191 PolarHBondContact O-N 3.11Å; E187-S191 PolarHBondContact O-OG 3.26Å; L188-S191 WeakPolarHBondContact O-CA 3.4Å; L188-S191 WeakPolarHBondContact O-CB 3.34Å; L188-S191 PolarHBondContact O-N 3.17Å; L189-S191 VanDerWaalsContact C-N 3.31Å; S191-T193 PolarHBondContact O-N 3.45Å
192	Y	54.9	Low	54.8	Low	26 Å²	26	56 Å²	56	10%	0.102	32%	0.316	C	S	.	.			trans	-72	129.3	177.1	-76	-87.7	0	0	0	111.5	H162 L188 L189 N196 A200 D203	H162-Y192 HydrophobicContact CB-CE1 4.47Å; H162-Y192 AromaticContact CE1-CD1 3.44Å; H162-Y192 VanDerWaalsContact CE1-CD1 3.44Å; H162-Y192 WeakPolarHBondContact CE1-CD1 3.36Å; H162-Y192 AromaticContact CE1-CE1 3.58Å; H162-Y192 AromaticContact CG-CE1 3.78Å; H162-Y192 AromaticContact CG-CZ 3.96Å; H162-Y192 AromaticContact ND1-CD1 3.83Å; H162-Y192 AromaticContact ND1-CE1 3.48Å; H162-Y192 WeakPolarHBondContact ND1-CE1 3.45Å; H162-Y192 AromaticContact NE2-CD1 3.83Å; H162-Y192 AromaticContact NE2-CE1 3.94Å; H162-Y192 AromaticContact NE2-CG 4Å; L188-Y192 HydrophobicContact CD2-CE2 4.5Å; L188-Y192 WeakPolarHBondContact O-CD2 3.46Å; L188-Y192 WeakPolarHBondContact O-CE2 3.21Å; L188-Y192 PolarHBondContact O-N 2.86Å; L189-Y192 HydrophobicContact CD2-CD2 4.44Å; L189-Y192 HydrophobicContact CD2-CE2 4.36Å; Y192-N196 HydrophobicContact CD1-CB 4.27Å; Y192-A200 HydrophobicContact CD1-CB 3.83Å; Y192-A200 HydrophobicContact CE1-CB 4.08Å; Y192-A200 HydrophobicContact CG-CB 4.11Å; Y192-D203 PolarHBondContact OH-OD2 3.49Å
193	T	49.2	Very low	55.2	Low	81 Å²	81	55 Å²	55	50%	0.497	31%	0.305	S	S	.	.			trans	-89	159.5	163.9	44.5	0	0	0	0	110.8	S191 D195 N196	S191-T193 PolarHBondContact O-N 3.45Å; T193-D195 PolarHBondContact O-N 3.33Å; T193-N196 PolarHBondContact O-N 2.81Å
194	E	45.1	Very low	55.1	Low	177 Å²	177	49.9 Å²	49.9	83%	0.827	28%	0.283	S	S	*	.	G	3₁₀ helix	trans	-58.8	-19.1	-172	-66.3	-179.6	160.9	0	0	114.4	A197	E194-A197 WeakPolarHBondContact O-CB 3.31Å
195	D	44.5	Very low	55.3	Low	146 Å²	146	52.2 Å²	52.2	78%	0.781	29%	0.293	S	S	*	.	G	3₁₀ helix	trans	-78.3	-23.1	-176.6	-63.7	-41.8	0	0	0	114.6	T193	T193-D195 PolarHBondContact O-N 3.33Å
196	N	50.3	Low	55.7	Low	26 Å²	26	57.9 Å²	57.9	14%	0.139	31%	0.314	C	S	.	.	G	3₁₀ helix	trans	-100.3	22.5	178.2	-78.1	27.5	0	0	0	112.9	E159 Y192 T193 S198 Q199 A200	E159-N196 PolarHBondContact OE1-ND2 2.9Å; Y192-N196 HydrophobicContact CD1-CB 4.27Å; T193-N196 PolarHBondContact O-N 2.81Å; N196-S198 PolarHBondContact O-N 3.3Å; N196-Q199 PolarHBondContact O-N 3.22Å; N196-Q199 VanDerWaalsContact O-N 3.1Å; N196-A200 PolarHBondContact O-N 3.3Å
197	A	46.7	Very low	55.7	Low	34 Å²	34	56 Å²	56	28%	0.281	30%	0.303	S	S	.	.	H	α-helix	trans	-53.5	-29.2	-175.5	0	0	0	0	0	114.1	E194 R201	E194-A197 WeakPolarHBondContact O-CB 3.31Å; A197-R201 WeakPolarHBondContact O-CG 3.39Å; A197-R201 PolarHBondContact O-N 2.86Å
198	S	53.7	Low	55.8	Low	86 Å²	86	54.8 Å²	54.8	60%	0.601	30%	0.297	S	S	*	.	H	α-helix	trans	-71.9	-44.3	178	58.2	0	0	0	0	113.2	N196 A200 R201	N196-S198 PolarHBondContact O-N 3.3Å; S198-A200 VanDerWaalsContact C-N 3.35Å; S198-R201 WeakPolarHBondContact O-CB 3.42Å; S198-R201 PolarHBondContact O-N 2.92Å
199	Q	53.2	Low	56.1	Low	82 Å²	82	56 Å²	56	38%	0.383	30%	0.304	S	S	.	.	H	α-helix	trans	-70.1	-35.9	175.2	-66.2	-175.3	2.9	0	0	111.1	R166 N196 R201 V202 D203	R166-Q199 VanDerWaalsContact NH2-OE1 3.16Å; N196-Q199 PolarHBondContact O-N 3.22Å; N196-Q199 VanDerWaalsContact O-N 3.1Å; Q199-R201 PolarHBondContact O-N 3.47Å; Q199-V202 PolarHBondContact O-N 3.46Å; Q199-D203 PolarHBondContact O-N 3.48Å; Q199-D203 VanDerWaalsContact O-N 3.12Å
200	A	54.5	Low	56.4	Low	5 Å²	5	58.6 Å²	58.6	4%	0.041	31%	0.314	C	S	.	.	H	α-helix	trans	-60.7	-27.6	173.1	0	0	0	0	0	112.7	Y192 N196 S198 A204	Y192-A200 HydrophobicContact CD1-CB 3.83Å; Y192-A200 HydrophobicContact CE1-CB 4.08Å; Y192-A200 HydrophobicContact CG-CB 4.11Å; N196-A200 PolarHBondContact O-N 3.3Å; S198-A200 VanDerWaalsContact C-N 3.35Å; A200-A204 WeakPolarHBondContact O-CB 3.4Å; A200-A204 PolarHBondContact O-N 3.43Å
201	R	59	Low	56.5	Low	94 Å²	94	56.8 Å²	56.8	36%	0.355	29%	0.294	S	S	.	.	H	α-helix	trans	-68	-48.7	175.7	-52	-151.7	178.5	176.3	0.4	112.3	A197 S198 Q199 D203 A204 H205 L232 E235	A197-R201 WeakPolarHBondContact O-CG 3.39Å; A197-R201 PolarHBondContact O-N 2.86Å; S198-R201 WeakPolarHBondContact O-CB 3.42Å; S198-R201 PolarHBondContact O-N 2.92Å; Q199-R201 PolarHBondContact O-N 3.47Å; R201-D203 VanDerWaalsContact C-N 3.3Å; R201-D203 PolarHBondContact O-N 2.91Å; R201-A204 PolarHBondContact O-N 3.46Å; R201-H205 WeakPolarHBondContact O-CB 3.4Å; R201-H205 PolarHBondContact O-CD2 3.32Å; R201-H205 PolarHBondContact O-N 2.87Å; R201-L232 HydrophobicContact CB-CD2 4.07Å; R201-L232 HydrophobicContact CG-CD2 3.76Å; R201-E235 WeakPolarHBondContact CD-OE1 3.45Å; R201-E235 IonicContact CZ-OE1 3.35Å; R201-E235 IonicContact NE-OE1 3.01Å; R201-E235 IonicContact NH1-OE1 3.51Å; R201-E235 PolarHBondContact NH1-OE1 3Å
202	V	63.1	Low	56.7	Low	89 Å²	89	55.9 Å²	55.9	54%	0.539	29%	0.287	S	S	.	.	H	α-helix	trans	-64.7	-41.1	-178.4	-179.7	0	0	0	0	110.2	Q199 H205 R206	Q199-V202 PolarHBondContact O-N 3.46Å; V202-H205 PolarHBondContact O-N 3.36Å; V202-R206 WeakPolarHBondContact O-CB 3.49Å; V202-R206 PolarHBondContact O-N 2.89Å
203	D	61	Low	57	Low	17 Å²	17	59.7 Å²	59.7	9%	0.091	30%	0.304	C	S	.	.	H	α-helix	trans	-65.9	-48.7	174.1	-70.7	-31.2	0	0	0	110.5	R166 Y192 Q199 R201 H205 R206 C207	R166-D203 WeakPolarHBondContact CD-OD1 3.18Å; R166-D203 IonicContact CZ-OD2 3.88Å; R166-D203 IonicContact NE-OD1 2.7Å; R166-D203 PolarHBondContact NE-OD1 3.26Å; R166-D203 IonicContact NE-OD2 3.72Å; R166-D203 PolarHBondContact NE-OD2 2.85Å; R166-D203 IonicContact NH2-OD2 2.69Å; R166-D203 PolarHBondContact NH2-OD2 2.82Å; Y192-D203 PolarHBondContact OH-OD2 3.49Å; Q199-D203 PolarHBondContact O-N 3.48Å; Q199-D203 VanDerWaalsContact O-N 3.12Å; R201-D203 VanDerWaalsContact C-N 3.3Å; R201-D203 PolarHBondContact O-N 2.91Å; D203-H205 VanDerWaalsContact C-N 3.3Å; D203-H205 PolarHBondContact O-N 3.24Å; D203-R206 PolarHBondContact O-N 2.88Å; D203-R206 VanDerWaalsContact O-N 3.1Å; D203-C207 WeakPolarHBondContact O-CB 3.35Å; D203-C207 PolarHBondContact O-N 2.87Å; D203-C207 PolarHBondContact O-SG 3.4Å
204	A	58.6	Low	57.3	Low	2 Å²	2	56.9 Å²	56.9	2%	0.017	29%	0.286	C	S	.	.	H	α-helix	trans	-57.2	-40.3	175.9	0	0	0	0	0	112.6	A200 R201 C207 I208 L232	A200-A204 WeakPolarHBondContact O-CB 3.4Å; A200-A204 PolarHBondContact O-N 3.43Å; R201-A204 PolarHBondContact O-N 3.46Å; A204-C207 WeakPolarHBondContact O-CB 3.48Å; A204-C207 PolarHBondContact O-N 3.36Å; A204-I208 WeakPolarHBondContact O-CB 3.4Å; A204-I208 WeakPolarHBondContact O-CG1 3.07Å; A204-I208 PolarHBondContact O-N 2.82Å; A204-L232 HydrophobicContact CB-CD1 3.58Å
205	H	63.6	Low	57.7	Low	52 Å²	52	52.3 Å²	52.3	24%	0.241	27%	0.272	C	S	.	.	H	α-helix	trans	-61.3	-50.1	173.4	-72.2	-41.4	0	0	0	111.9	R201 V202 D203 C207 I208 V209 E235 I237	R201-H205 WeakPolarHBondContact O-CB 3.4Å; R201-H205 PolarHBondContact O-CD2 3.32Å; R201-H205 PolarHBondContact O-N 2.87Å; V202-H205 PolarHBondContact O-N 3.36Å; D203-H205 VanDerWaalsContact C-N 3.3Å; D203-H205 PolarHBondContact O-N 3.24Å; H205-C207 PolarHBondContact O-N 2.91Å; H205-I208 PolarHBondContact O-N 3.22Å; H205-V209 WeakPolarHBondContact O-CB 3.37Å; H205-V209 WeakPolarHBondContact O-CG2 3.37Å; H205-V209 PolarHBondContact O-N 2.99Å; H205-E235 IonicContact CE1-OE2 3.38Å; H205-E235 PolarHBondContact CE1-OE2 3.23Å; H205-E235 IonicContact NE2-OE2 2.74Å; H205-E235 PolarHBondContact NE2-OE2 3Å; H205-E235 VanDerWaalsContact NE2-OE2 3.08Å; H205-I237 HydrophobicContact CB-CD1 4.03Å; H205-I237 WeakPolarHBondContact ND1-CD1 3.24Å
206	R	62.9	Low	57.8	Low	135 Å²	135	51 Å²	51	51%	0.509	27%	0.265	S	S	.	.	H	α-helix	trans	-60.5	-37.3	177.1	-168	179.5	-73.2	-166.6	-0.7	111.1	E170 V202 D203 R210	E170-R206 IonicContact OE1-NH1 3.19Å; E170-R206 PolarHBondContact OE1-NH1 3.38Å; V202-R206 WeakPolarHBondContact O-CB 3.49Å; V202-R206 PolarHBondContact O-N 2.89Å; D203-R206 PolarHBondContact O-N 2.88Å; D203-R206 VanDerWaalsContact O-N 3.1Å; R206-R210 VanDerWaalsContact O-CB 3.27Å; R206-R210 WeakPolarHBondContact O-CB 3.38Å; R206-R210 PolarHBondContact O-N 3.4Å
207	C	59.2	Low	58.1	Low	7 Å²	7	51 Å²	51	5%	0.047	27%	0.267	C	S	.	.	H	α-helix	trans	-66.1	-46	176.6	-65	0	0	0	0	112.7	M185 D203 A204 H205 R210 A211	M185-C207 WeakPolarHBondContact CE-SG 3.44Å; M185-C207 HydrophobicContact CG-CB 4.29Å; M185-C207 VanDerWaalsContact CG-SG 3.54Å; M185-C207 PolarHBondContact SD-SG 2.86Å; D203-C207 WeakPolarHBondContact O-CB 3.35Å; D203-C207 PolarHBondContact O-N 2.87Å; D203-C207 PolarHBondContact O-SG 3.4Å; A204-C207 WeakPolarHBondContact O-CB 3.48Å; A204-C207 PolarHBondContact O-N 3.36Å; H205-C207 PolarHBondContact O-N 2.91Å; C207-R210 PolarHBondContact O-N 3.37Å; C207-A211 WeakPolarHBondContact O-CB 3.03Å; C207-A211 PolarHBondContact O-N 3.41Å
208	I	62.1	Low	58.5	Low	8 Å²	8	50.1 Å²	50.1	4%	0.041	26%	0.257	C	S	.	.	H	α-helix	trans	-67.6	-45.3	-179.6	-66.6	166	0	0	0	109.4	A204 H205 R210 A211 L212 I237 L241	A204-I208 WeakPolarHBondContact O-CB 3.4Å; A204-I208 WeakPolarHBondContact O-CG1 3.07Å; A204-I208 PolarHBondContact O-N 2.82Å; H205-I208 PolarHBondContact O-N 3.22Å; I208-R210 VanDerWaalsContact C-N 3.26Å; I208-R210 PolarHBondContact O-N 2.89Å; I208-A211 PolarHBondContact O-N 2.9Å; I208-L212 HydrophobicContact CG2-CD1 3.94Å; I208-L212 HydrophobicContact CG2-CG 4.31Å; I208-L212 WeakPolarHBondContact O-CB 3.3Å; I208-L212 WeakPolarHBondContact O-CG 3.42Å; I208-L212 PolarHBondContact O-N 3.08Å; I208-I237 HydrophobicContact CB-CG2 3.69Å; I208-I237 HydrophobicContact CD1-CG2 3.39Å; I208-I237 HydrophobicContact CG1-CG2 4.11Å; I208-I237 HydrophobicContact CG2-CG2 3.51Å; I208-L241 HydrophobicContact CD1-CD1 3.91Å; I208-L241 HydrophobicContact CG1-CD1 3.72Å; I208-L241 HydrophobicContact CG2-CD1 4.06Å
209	V	66	Low	58.5	Low	27 Å²	27	49.7 Å²	49.7	16%	0.164	25%	0.247	C	C	.	.	H	α-helix	trans	-58.3	-40.6	175.8	174.6	0	0	0	0	111	H205 L212 K213 L266 L268	H205-V209 WeakPolarHBondContact O-CB 3.37Å; H205-V209 WeakPolarHBondContact O-CG2 3.37Å; H205-V209 PolarHBondContact O-N 2.99Å; V209-L212 PolarHBondContact O-N 3Å; V209-K213 WeakPolarHBondContact O-CB 3.46Å; V209-K213 PolarHBondContact O-N 3.07Å; V209-L266 HydrophobicContact CG1-CB 4.44Å; V209-L266 HydrophobicContact CG1-CD2 4.4Å; V209-L266 HydrophobicContact CG2-CD1 4.04Å; V209-L266 HydrophobicContact CG2-CD2 3.62Å; V209-L266 HydrophobicContact CG2-CG 4.3Å; V209-L268 HydrophobicContact CG1-CD1 4.31Å; V209-L268 HydrophobicContact CG1-CG 4.35Å
210	R	62.3	Low	58.6	Low	58 Å²	58	46 Å²	46	22%	0.219	23%	0.23	C	C	.	.	H	α-helix	trans	-74.6	-40.3	178.4	-173.2	64.1	-167.7	-160.5	-2.4	113.3	Y169 R206 C207 I208 L212 K213 D214	Y169-R210 VanDerWaalsContact OH-CB 3.31Å; Y169-R210 WeakPolarHBondContact OH-CB 3.27Å; Y169-R210 VanDerWaalsContact OH-CG 3.25Å; Y169-R210 WeakPolarHBondContact OH-CG 3.33Å; R206-R210 VanDerWaalsContact O-CB 3.27Å; R206-R210 WeakPolarHBondContact O-CB 3.38Å; R206-R210 PolarHBondContact O-N 3.4Å; C207-R210 PolarHBondContact O-N 3.37Å; I208-R210 VanDerWaalsContact C-N 3.26Å; I208-R210 PolarHBondContact O-N 2.89Å; R210-L212 PolarHBondContact O-N 3.24Å; R210-K213 CarbonylContact O-C 3.56Å; R210-K213 PolarHBondContact O-N 2.88Å; R210-K213 VanDerWaalsContact O-N 3.07Å; R210-D214 IonicContact CZ-OD1 3.72Å; R210-D214 IonicContact NE-OD1 2.85Å; R210-D214 PolarHBondContact NE-OD1 3.35Å; R210-D214 IonicContact NE-OD2 2.83Å; R210-D214 IonicContact NH2-OD1 3.22Å; R210-D214 PolarHBondContact NH2-OD1 2.84Å; R210-D214 PolarHBondContact O-N 3.33Å
211	A	59.8	Low	58.5	Low	15 Å²	15	47.6 Å²	47.6	12%	0.124	24%	0.238	C	C	.	.	H	α-helix	trans	-62.7	-31.2	173.5	0	0	0	0	0	111.5	C207 I208 F220 L223 K276	C207-A211 WeakPolarHBondContact O-CB 3.03Å; C207-A211 PolarHBondContact O-N 3.41Å; I208-A211 PolarHBondContact O-N 2.9Å; A211-F220 HydrophobicContact CB-CE1 4.02Å; A211-L223 HydrophobicContact CB-CD1 4.47Å; A211-K276 PolarHBondContact O-NZ 3.45Å
212	L	60.5	Low	58.3	Low	6 Å²	6	48.2 Å²	48.2	3%	0.031	25%	0.245	C	C	.	.	H	α-helix	trans	-70.9	-41.7	170.3	-70.1	173.2	0	0	0	111.6	I208 V209 R210 D214 F220 L240 F244 L268	I208-L212 HydrophobicContact CG2-CD1 3.94Å; I208-L212 HydrophobicContact CG2-CG 4.31Å; I208-L212 WeakPolarHBondContact O-CB 3.3Å; I208-L212 WeakPolarHBondContact O-CG 3.42Å; I208-L212 PolarHBondContact O-N 3.08Å; V209-L212 PolarHBondContact O-N 3Å; R210-L212 PolarHBondContact O-N 3.24Å; L212-D214 VanDerWaalsContact C-N 3.33Å; L212-D214 PolarHBondContact O-N 2.75Å; L212-F220 HydrophobicContact CD2-CZ 4.2Å; L212-L240 HydrophobicContact CD1-CD2 3.7Å; L212-L240 HydrophobicContact CD1-CG 4.43Å; L212-F244 HydrophobicContact CD2-CD1 4.04Å; L212-F244 HydrophobicContact CD2-CD2 3.67Å; L212-F244 HydrophobicContact CD2-CE1 3.84Å; L212-F244 HydrophobicContact CD2-CE2 3.46Å; L212-F244 VanDerWaalsContact CD2-CE2 3.46Å; L212-F244 HydrophobicContact CD2-CG 3.96Å; L212-F244 HydrophobicContact CD2-CZ 3.56Å; L212-L268 HydrophobicContact CB-CD2 3.67Å; L212-L268 HydrophobicContact CD1-CD1 4.39Å
213	K	61.1	Low	57.9	Low	106 Å²	106	44.9 Å²	44.9	46%	0.461	22%	0.224	S	C	.	.	H	α-helix	trans	-67.1	-29.3	177.1	-170.6	168.6	-177.9	167.6	0	113.7	V209 R210 P215	V209-K213 WeakPolarHBondContact O-CB 3.46Å; V209-K213 PolarHBondContact O-N 3.07Å; R210-K213 CarbonylContact O-C 3.56Å; R210-K213 PolarHBondContact O-N 2.88Å; R210-K213 VanDerWaalsContact O-N 3.07Å; K213-P215 WeakPolarHBondContact O-CD 3.27Å
214	D	56.9	Low	57.6	Low	22 Å²	22	46 Å²	46	12%	0.118	23%	0.23	C	C	.	.			trans	-78.5	119.1	179.7	-77.6	-20.5	0	0	0	110.9	S178 R210 L212 N216 K276	S178-D214 WeakPolarHBondContact CB-OD2 3.36Å; S178-D214 PolarHBondContact OG-OD2 3.47Å; R210-D214 IonicContact CZ-OD1 3.72Å; R210-D214 IonicContact NE-OD1 2.85Å; R210-D214 PolarHBondContact NE-OD1 3.35Å; R210-D214 IonicContact NE-OD2 2.83Å; R210-D214 IonicContact NH2-OD1 3.22Å; R210-D214 PolarHBondContact NH2-OD1 2.84Å; R210-D214 PolarHBondContact O-N 3.33Å; L212-D214 VanDerWaalsContact C-N 3.33Å; L212-D214 PolarHBondContact O-N 2.75Å; D214-N216 PolarHBondContact O-N 2.95Å; D214-K276 PolarHBondContact O-NZ 3.03Å
215	P	51.8	Low	57.4	Low	81 Å²	81	50.3 Å²	50.3	53%	0.526	26%	0.256	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.9	-5.5	-175.5	30.9	-35.9	0	0	0	113.5	K213 F218	K213-P215 WeakPolarHBondContact O-CD 3.27Å; P215-F218 WeakPolarHBondContact O-CE2 3.25Å; P215-F218 WeakPolarHBondContact O-CZ 3.5Å
216	N	48	Very low	57.1	Low	118 Å²	118	48.9 Å²	48.9	63%	0.631	25%	0.25	S	S	*	.	T	Hydrogen-bonded Turn	trans	-107.8	-10.4	-177.1	-68.8	-16.9	0	0	0	113.9	D214 F218	D214-N216 PolarHBondContact O-N 2.95Å; N216-F218 WeakPolarHBondContact O-CD2 3.39Å; N216-F218 PolarHBondContact O-N 3.46Å
217	S	56	Low	56.4	Low	28 Å²	28	50.5 Å²	50.5	20%	0.196	26%	0.261	C	S	.	.			trans	-95.1	98.3	179.3	-170.2	0	0	0	0	110.3	K276	S217-K276 WeakPolarHBondContact O-CE 3.11Å; S217-K276 PolarHBondContact O-NZ 3.48Å
218	F	54.6	Low	55.7	Low	15 Å²	15	51.5 Å²	51.5	7%	0.066	27%	0.267	C	S	.	.			trans	-107.1	-10.5	178.9	-61.2	-83.8	0	0	0	113.1	P215 N216 F220 K276 L279 L280 T319 M321	P215-F218 WeakPolarHBondContact O-CE2 3.25Å; P215-F218 WeakPolarHBondContact O-CZ 3.5Å; N216-F218 WeakPolarHBondContact O-CD2 3.39Å; N216-F218 PolarHBondContact O-N 3.46Å; F218-F220 PolarHBondContact O-N 2.75Å; F218-K276 HydrophobicContact CD1-CG 4.11Å; F218-K276 HydrophobicContact CE1-CD 4.37Å; F218-K276 HydrophobicContact CE1-CG 3.81Å; F218-L279 HydrophobicContact CD1-CD2 3.97Å; F218-L279 HydrophobicContact CE1-CB 4.48Å; F218-L279 HydrophobicContact CE1-CD2 3.34Å; F218-L279 HydrophobicContact CE1-CG 4.37Å; F218-L279 HydrophobicContact CE2-CD2 4.16Å; F218-L279 HydrophobicContact CZ-CD2 3.42Å; F218-L279 VanDerWaalsContact CZ-CD2 3.42Å; F218-L280 HydrophobicContact CB-CD2 4.18Å; F218-L280 HydrophobicContact CD1-CD2 4.14Å; F218-L280 HydrophobicContact CD1-CG 4.31Å; F218-T319 HydrophobicContact CD2-CG2 4.02Å; F218-T319 HydrophobicContact CE2-CG2 3.22Å; F218-T319 HydrophobicContact CZ-CG2 3.65Å; F218-M321 HydrophobicContact CB-CE 4.48Å; F218-M321 HydrophobicContact CB-SD 3.95Å; F218-M321 HydrophobicContact CD2-CE 3.59Å; F218-M321 HydrophobicContact CD2-SD 3.53Å; F218-M321 VanDerWaalsContact CD2-SD 3.53Å; F218-M321 HydrophobicContact CE2-CE 4.32Å; F218-M321 HydrophobicContact CE2-SD 4.32Å; F218-M321 HydrophobicContact CG-CE 4.47Å; F218-M321 HydrophobicContact CG-SD 4Å
219	L	54.3	Low	55.2	Low	76 Å²	76	51.3 Å²	51.3	40%	0.398	27%	0.266	S	S	.	.			trans	-94.2	83.7	-179.4	-67.1	169.6	0	0	0	110.2	D221 T339	L219-D221 PolarHBondContact O-N 3.36Å; L219-T339 HydrophobicContact CD2-CG2 4.36Å
220	F	55.3	Low	54.6	Low	5 Å²	5	57.2 Å²	57.2	2%	0.022	29%	0.286	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80.5	-2	174.4	-59.2	-73.7	0	0	0	113.5	A211 L212 F218 H222 L223 L224 F244 V245 L280	A211-F220 HydrophobicContact CB-CE1 4.02Å; L212-F220 HydrophobicContact CD2-CZ 4.2Å; F218-F220 PolarHBondContact O-N 2.75Å; F220-H222 VanDerWaalsContact C-N 3.26Å; F220-H222 PolarHBondContact O-N 3.13Å; F220-L223 HydrophobicContact CD1-CD1 4.11Å; F220-L223 WeakPolarHBondContact O-CB 3.41Å; F220-L223 PolarHBondContact O-N 3.34Å; F220-L224 PolarHBondContact O-N 3.5Å; F220-F244 HydrophobicContact CE2-CD1 4.18Å; F220-V245 HydrophobicContact CB-CG2 3.68Å; F220-L280 HydrophobicContact CE2-CD1 4.07Å
221	D	52.2	Low	54	Low	38 Å²	38	61.3 Å²	61.3	20%	0.203	31%	0.305	C	S	.	.	H	α-helix	trans	-61	-34.9	-177.2	-157.7	18.1	0	0	0	112.8	L219 L223 L224 T225 F343	L219-D221 PolarHBondContact O-N 3.36Å; D221-L223 PolarHBondContact O-N 3.1Å; D221-L224 PolarHBondContact O-N 2.97Å; D221-T225 PolarHBondContact O-N 3.34Å; D221-T225 PolarHBondContact O-OG1 3.04Å; D221-F343 PolarHBondContact OD2-N 3.28Å
222	H	54	Low	53.7	Low	108 Å²	108	61.2 Å²	61.2	50%	0.5	30%	0.302	S	S	.	.	H	α-helix	trans	-67.1	-22.7	175.4	-60.7	90.7	0	0	0	113.1	V186 F220 T225 L226	V186-H222 HydrophobicContact CG2-CB 4.15Å; F220-H222 VanDerWaalsContact C-N 3.26Å; F220-H222 PolarHBondContact O-N 3.13Å; H222-T225 WeakPolarHBondContact CA-OG1 3.16Å; H222-T225 PolarHBondContact O-OG1 3Å; H222-L226 VanDerWaalsContact O-CD1 3.31Å; H222-L226 WeakPolarHBondContact O-CD1 3.41Å; H222-L226 VanDerWaalsContact O-CG 3.31Å; H222-L226 WeakPolarHBondContact O-CG 3.4Å
223	L	55.4	Low	53	Low	19 Å²	19	67 Å²	67	10%	0.099	33%	0.33	C	S	.	.	H	α-helix	trans	-83.6	-35.3	176.8	-65.2	172.4	0	0	0	111.5	L189 A211 F220 D221 T225 L226 V229 L241	L189-L223 HydrophobicContact CD1-CD2 4.05Å; A211-L223 HydrophobicContact CB-CD1 4.47Å; F220-L223 HydrophobicContact CD1-CD1 4.11Å; F220-L223 WeakPolarHBondContact O-CB 3.41Å; F220-L223 PolarHBondContact O-N 3.34Å; D221-L223 PolarHBondContact O-N 3.1Å; L223-T225 VanDerWaalsContact C-N 3.31Å; L223-T225 PolarHBondContact O-N 3.32Å; L223-L226 HydrophobicContact CD2-CD1 4.3Å; L223-L226 PolarHBondContact O-N 2.78Å; L223-V229 WeakPolarHBondContact O-CB 3.26Å; L223-V229 VanDerWaalsContact O-CG2 3.25Å; L223-V229 WeakPolarHBondContact O-CG2 3.43Å; L223-L241 HydrophobicContact CB-CD1 4.41Å; L223-L241 HydrophobicContact CD1-CD1 4.06Å
224	L	54.2	Low	52.5	Low	40 Å²	40	65.1 Å²	65.1	21%	0.209	34%	0.34	C	S	.	.	H	α-helix	trans	-70.8	-23.9	177.5	-74.8	178.7	0	0	0	114.2	F220 D221 L226 R230 L241 V245	F220-L224 PolarHBondContact O-N 3.5Å; D221-L224 PolarHBondContact O-N 2.97Å; L224-L226 VanDerWaalsContact C-N 3.26Å; L224-R230 PolarHBondContact O-NE 3.43Å; L224-L241 HydrophobicContact CD2-CD2 3.42Å; L224-L241 VanDerWaalsContact CD2-CD2 3.42Å; L224-L241 HydrophobicContact CG-CD2 3.83Å; L224-V245 HydrophobicContact CD1-CB 3.78Å; L224-V245 HydrophobicContact CD1-CG1 3.48Å; L224-V245 VanDerWaalsContact CD1-CG1 3.48Å; L224-V245 HydrophobicContact CD1-CG2 3.65Å; L224-V245 HydrophobicContact CG-CG2 4.28Å
225	T	55.5	Low	52.7	Low	93 Å²	93	66.5 Å²	66.5	57%	0.571	35%	0.346	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.2	-16.6	176.7	12.3	0	0	0	0	112.7	D221 H222 L223	D221-T225 PolarHBondContact O-N 3.34Å; D221-T225 PolarHBondContact O-OG1 3.04Å; H222-T225 WeakPolarHBondContact CA-OG1 3.16Å; H222-T225 PolarHBondContact O-OG1 3Å; L223-T225 VanDerWaalsContact C-N 3.31Å; L223-T225 PolarHBondContact O-N 3.32Å
226	L	56.8	Low	53.1	Low	22 Å²	22	66.1 Å²	66.1	12%	0.115	34%	0.339	C	S	.	.	S	Bend	trans	-81.7	124.9	-176.9	-63.6	165.5	0	0	0	110.2	V186 L189 H222 L223 L224 P228 V229 R230	V186-L226 HydrophobicContact CG1-CD1 4.41Å; L189-L226 HydrophobicContact CB-CD1 3.67Å; L189-L226 HydrophobicContact CD1-CD1 4.09Å; H222-L226 VanDerWaalsContact O-CD1 3.31Å; H222-L226 WeakPolarHBondContact O-CD1 3.41Å; H222-L226 VanDerWaalsContact O-CG 3.31Å; H222-L226 WeakPolarHBondContact O-CG 3.4Å; L223-L226 HydrophobicContact CD2-CD1 4.3Å; L223-L226 PolarHBondContact O-N 2.78Å; L224-L226 VanDerWaalsContact C-N 3.26Å; L226-P228 VanDerWaalsContact C-N 3.31Å; L226-V229 HydrophobicContact CB-CG2 4.36Å; L226-V229 PolarHBondContact O-N 3.06Å; L226-R230 PolarHBondContact O-N 3.4Å
227	K	47.6	Very low	53.9	Low	169 Å²	169	61 Å²	61	74%	0.735	31%	0.311	S	S	*	.	H	α-helix	trans	-53.8	-36.3	179.5	-61.5	179.8	-178.7	177.2	0	114.1	V229 R230 F231	K227-V229 PolarHBondContact O-N 2.73Å; K227-R230 PolarHBondContact O-N 3.35Å; K227-F231 PolarHBondContact O-N 2.76Å
228	P	46.2	Very low	54.2	Low	28 Å²	28	60.6 Å²	60.6	18%	0.182	31%	0.307	C	S	.	.	H	α-helix	trans	-61.3	-29.8	175.2	-25	35.2	0	0	0	114	L226 F231 L232	L226-P228 VanDerWaalsContact C-N 3.31Å; P228-F231 PolarHBondContact O-N 3.23Å; P228-L232 WeakPolarHBondContact O-CD1 3.3Å; P228-L232 VanDerWaalsContact O-CG 3.32Å; P228-L232 WeakPolarHBondContact O-CG 3.35Å; P228-L232 PolarHBondContact O-N 3.44Å
229	V	50.7	Low	54.7	Low	4 Å²	4	63.6 Å²	63.6	2%	0.024	32%	0.323	C	S	.	.	H	α-helix	trans	-78	-34.1	178.9	-179.2	0	0	0	0	111.2	L223 L226 K227 F231 L232 H238	L223-V229 WeakPolarHBondContact O-CB 3.26Å; L223-V229 VanDerWaalsContact O-CG2 3.25Å; L223-V229 WeakPolarHBondContact O-CG2 3.43Å; L226-V229 HydrophobicContact CB-CG2 4.36Å; L226-V229 PolarHBondContact O-N 3.06Å; K227-V229 PolarHBondContact O-N 2.73Å; V229-F231 VanDerWaalsContact C-N 3.28Å; V229-F231 PolarHBondContact O-N 2.84Å; V229-L232 WeakPolarHBondContact O-CB 3.24Å; V229-L232 PolarHBondContact O-N 3.36Å; V229-L232 VanDerWaalsContact O-N 3.12Å; V229-H238 PolarHBondContact O-CD2 3.31Å
230	R	54.4	Low	55.3	Low	150 Å²	150	60.1 Å²	60.1	57%	0.566	31%	0.305	S	S	*	.	H	α-helix	trans	-67.2	-29.5	169.4	-63.7	-174.1	-177.4	-172.8	-3.5	112.7	L224 L226 K227 L232 E233	L224-R230 PolarHBondContact O-NE 3.43Å; L226-R230 PolarHBondContact O-N 3.4Å; K227-R230 PolarHBondContact O-N 3.35Å; R230-L232 PolarHBondContact O-N 3.11Å; R230-E233 WeakPolarHBondContact O-CB 3.1Å; R230-E233 WeakPolarHBondContact O-CG 3.33Å; R230-E233 PolarHBondContact O-N 3.2Å
231	F	49.4	Very low	55.7	Low	145 Å²	145	60 Å²	60	64%	0.636	31%	0.305	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.1	-15.1	173.1	-157.7	-96.4	0	0	0	113	K227 P228 V229 E233	K227-F231 PolarHBondContact O-N 2.76Å; P228-F231 PolarHBondContact O-N 3.23Å; V229-F231 VanDerWaalsContact C-N 3.28Å; V229-F231 PolarHBondContact O-N 2.84Å; F231-E233 VanDerWaalsContact C-N 3.31Å
232	L	53.1	Low	56.4	Low	12 Å²	12	60.6 Å²	60.6	6%	0.063	31%	0.31	C	S	.	.	T	Hydrogen-bonded Turn	trans	-90.7	10.3	173.7	-70.2	161.1	0	0	0	112.7	R201 A204 P228 V229 R230 G234 E235 H238	R201-L232 HydrophobicContact CB-CD2 4.07Å; R201-L232 HydrophobicContact CG-CD2 3.76Å; A204-L232 HydrophobicContact CB-CD1 3.58Å; P228-L232 WeakPolarHBondContact O-CD1 3.3Å; P228-L232 VanDerWaalsContact O-CG 3.32Å; P228-L232 WeakPolarHBondContact O-CG 3.35Å; P228-L232 PolarHBondContact O-N 3.44Å; V229-L232 WeakPolarHBondContact O-CB 3.24Å; V229-L232 PolarHBondContact O-N 3.36Å; V229-L232 VanDerWaalsContact O-N 3.12Å; R230-L232 PolarHBondContact O-N 3.11Å; L232-G234 PolarHBondContact O-N 3.02Å; L232-E235 WeakPolarHBondContact CD2-OE2 3.4Å; L232-E235 PolarHBondContact O-N 3.41Å; L232-H238 WeakPolarHBondContact O-CB 3.28Å
233	E	45.5	Very low	57.2	Low	129 Å²	129	56.7 Å²	56.7	60%	0.603	29%	0.292	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59	104.2	173.4	-76.8	170.3	-161	0	0	110.1	R230 F231	R230-E233 WeakPolarHBondContact O-CB 3.1Å; R230-E233 WeakPolarHBondContact O-CG 3.33Å; R230-E233 PolarHBondContact O-N 3.2Å; F231-E233 VanDerWaalsContact C-N 3.31Å
234	G	51.4	Low	57.6	Low	66 Å²	66	55.9 Å²	55.9	68%	0.68	29%	0.288	S	S	*	.	T	Hydrogen-bonded Turn	trans	130.3	-11	178.7	0	0	0	0	0	115.6	L232	L232-G234 PolarHBondContact O-N 3.02Å
235	E	60.7	Low	58	Low	50 Å²	50	54.5 Å²	54.5	23%	0.234	28%	0.281	C	S	.	.	S	Bend	trans	-87.7	145.7	171.3	-73.6	175.4	-178.2	0	0	111.1	R201 H205 L232 I237 H238 D239	R201-E235 WeakPolarHBondContact CD-OE1 3.45Å; R201-E235 IonicContact CZ-OE1 3.35Å; R201-E235 IonicContact NE-OE1 3.01Å; R201-E235 IonicContact NH1-OE1 3.51Å; R201-E235 PolarHBondContact NH1-OE1 3Å; H205-E235 IonicContact CE1-OE2 3.38Å; H205-E235 PolarHBondContact CE1-OE2 3.23Å; H205-E235 IonicContact NE2-OE2 2.74Å; H205-E235 PolarHBondContact NE2-OE2 3Å; H205-E235 VanDerWaalsContact NE2-OE2 3.08Å; L232-E235 WeakPolarHBondContact CD2-OE2 3.4Å; L232-E235 PolarHBondContact O-N 3.41Å; E235-I237 PolarHBondContact O-N 3.42Å; E235-H238 WeakPolarHBondContact O-CB 3.25Å; E235-H238 PolarHBondContact O-N 3Å; E235-D239 PolarHBondContact O-N 2.74Å; E235-D239 VanDerWaalsContact O-N 3.11Å
236	L	60.6	Low	58	Low	73 Å²	73	54.7 Å²	54.7	38%	0.382	29%	0.286	S	S	.	.	H	α-helix	trans	-51.4	-27.3	-179.3	-87.1	112.6	0	0	0	113.7	L240 F255 N259 F262	L236-L240 VanDerWaalsContact O-CB 3.29Å; L236-L240 WeakPolarHBondContact O-CB 3.33Å; L236-L240 PolarHBondContact O-N 2.88Å; L236-F255 HydrophobicContact CB-CZ 4.38Å; L236-F255 HydrophobicContact CD2-CE2 4.39Å; L236-F255 HydrophobicContact CD2-CZ 3.82Å; L236-F255 HydrophobicContact CG-CZ 4.46Å; L236-N259 HydrophobicContact CD2-CB 4.25Å; L236-N259 VanDerWaalsContact CD2-CG 3.41Å; L236-N259 WeakPolarHBondContact CD2-ND2 3.43Å; L236-N259 WeakPolarHBondContact CD2-OD1 3.15Å; L236-F262 HydrophobicContact CB-CE1 4.42Å
237	I	64.3	Low	58.1	Low	10 Å²	10	54.8 Å²	54.8	5%	0.051	29%	0.29	C	S	.	.	H	α-helix	trans	-77.4	-35	179	-70.6	175.4	0	0	0	111.7	H205 I208 E235 L240 L241 F262	H205-I237 HydrophobicContact CB-CD1 4.03Å; H205-I237 WeakPolarHBondContact ND1-CD1 3.24Å; I208-I237 HydrophobicContact CB-CG2 3.69Å; I208-I237 HydrophobicContact CD1-CG2 3.39Å; I208-I237 HydrophobicContact CG1-CG2 4.11Å; I208-I237 HydrophobicContact CG2-CG2 3.51Å; E235-I237 PolarHBondContact O-N 3.42Å; I237-L240 PolarHBondContact O-N 3.31Å; I237-L241 WeakPolarHBondContact O-CB 3.47Å; I237-L241 PolarHBondContact O-N 2.86Å; I237-F262 HydrophobicContact CD1-CE1 4.05Å; I237-F262 HydrophobicContact CD1-CZ 3.57Å; I237-F262 HydrophobicContact CG1-CE1 3.62Å; I237-F262 HydrophobicContact CG1-CZ 3.56Å
238	H	61.9	Low	58.7	Low	21 Å²	21	52.2 Å²	52.2	10%	0.097	28%	0.279	C	S	.	.	H	α-helix	trans	-69.6	-39.6	172.2	-178.8	-85.7	0	0	0	110.7	V229 L232 E235 L240 L241 T242	V229-H238 PolarHBondContact O-CD2 3.31Å; L232-H238 WeakPolarHBondContact O-CB 3.28Å; E235-H238 WeakPolarHBondContact O-CB 3.25Å; E235-H238 PolarHBondContact O-N 3Å; H238-L240 VanDerWaalsContact C-N 3.32Å; H238-L240 PolarHBondContact O-N 3.09Å; H238-L241 PolarHBondContact O-N 3.23Å; H238-T242 PolarHBondContact CE1-OG1 2.86Å; H238-T242 PolarHBondContact ND1-OG1 3.4Å; H238-T242 VanDerWaalsContact O-CB 3.3Å; H238-T242 WeakPolarHBondContact O-CB 3.42Å; H238-T242 PolarHBondContact O-N 3.36Å; H238-T242 PolarHBondContact O-OG1 2.86Å
239	D	65.6	Low	59.3	Low	77 Å²	77	51.1 Å²	51.1	41%	0.412	27%	0.271	S	S	.	.	H	α-helix	trans	-62.6	-41.9	172.9	-75.6	-7.6	0	0	0	111	E235 T242 I243 F255	E235-D239 PolarHBondContact O-N 2.74Å; E235-D239 VanDerWaalsContact O-N 3.11Å; D239-T242 PolarHBondContact O-N 3.43Å; D239-I243 WeakPolarHBondContact O-CB 3.44Å; D239-I243 WeakPolarHBondContact O-CD1 3.4Å; D239-I243 WeakPolarHBondContact O-CG1 3.36Å; D239-I243 PolarHBondContact O-N 2.7Å; D239-F255 HydrophobicContact CB-CE2 4.26Å
240	L	66.9	Low	59.9	Low	4 Å²	4	53.7 Å²	53.7	2%	0.021	29%	0.293	C	S	.	.	H	α-helix	trans	-60.9	-47.3	173.4	-172.3	63.1	0	0	0	111.1	L212 L236 I237 H238 T242 I243 F244 Y252 F255	L212-L240 HydrophobicContact CD1-CD2 3.7Å; L212-L240 HydrophobicContact CD1-CG 4.43Å; L236-L240 VanDerWaalsContact O-CB 3.29Å; L236-L240 WeakPolarHBondContact O-CB 3.33Å; L236-L240 PolarHBondContact O-N 2.88Å; I237-L240 PolarHBondContact O-N 3.31Å; H238-L240 VanDerWaalsContact C-N 3.32Å; H238-L240 PolarHBondContact O-N 3.09Å; L240-T242 VanDerWaalsContact C-N 3.34Å; L240-T242 PolarHBondContact O-N 3.42Å; L240-I243 WeakPolarHBondContact O-CB 3.11Å; L240-I243 PolarHBondContact O-N 2.88Å; L240-F244 HydrophobicContact CD1-CD2 4.03Å; L240-F244 HydrophobicContact CD1-CE2 3.84Å; L240-F244 HydrophobicContact CG-CD2 3.95Å; L240-F244 HydrophobicContact CG-CE2 4Å; L240-F244 WeakPolarHBondContact O-CB 3.44Å; L240-F244 VanDerWaalsContact O-CD2 3.27Å; L240-F244 WeakPolarHBondContact O-CD2 3.07Å; L240-F244 PolarHBondContact O-N 3.22Å; L240-Y252 HydrophobicContact CD1-CD2 4.15Å; L240-Y252 HydrophobicContact CD1-CE2 3.91Å; L240-F255 HydrophobicContact CB-CE1 4.25Å; L240-F255 HydrophobicContact CB-CZ 4.41Å; L240-F255 HydrophobicContact CD1-CD1 3.91Å; L240-F255 HydrophobicContact CD1-CE1 3.83Å
241	L	63.8	Low	60.5	Low	3 Å²	3	48.3 Å²	48.3	2%	0.016	28%	0.281	C	S	.	.	H	α-helix	trans	-64.4	-38.3	178.4	-169	135.4	0	0	0	112	I208 L223 L224 I237 H238 F244 V245	I208-L241 HydrophobicContact CD1-CD1 3.91Å; I208-L241 HydrophobicContact CG1-CD1 3.72Å; I208-L241 HydrophobicContact CG2-CD1 4.06Å; L223-L241 HydrophobicContact CB-CD1 4.41Å; L223-L241 HydrophobicContact CD1-CD1 4.06Å; L224-L241 HydrophobicContact CD2-CD2 3.42Å; L224-L241 VanDerWaalsContact CD2-CD2 3.42Å; L224-L241 HydrophobicContact CG-CD2 3.83Å; I237-L241 WeakPolarHBondContact O-CB 3.47Å; I237-L241 PolarHBondContact O-N 2.86Å; H238-L241 PolarHBondContact O-N 3.23Å; L241-F244 CarbonylContact O-C 3.41Å; L241-F244 WeakPolarHBondContact O-CA 3.15Å; L241-F244 WeakPolarHBondContact O-CB 3.06Å; L241-F244 PolarHBondContact O-N 3.5Å; L241-F244 VanDerWaalsContact O-N 3.14Å; L241-V245 HydrophobicContact CD2-CG2 4.4Å; L241-V245 WeakPolarHBondContact O-CG2 3.16Å; L241-V245 PolarHBondContact O-N 3.09Å
242	T	67.5	Low	61.4	Low	50 Å²	50	41.5 Å²	41.5	31%	0.307	25%	0.251	S	S	.	.	H	α-helix	trans	-65.2	-38.6	173.5	-57.7	0	0	0	0	111.1	H238 D239 L240 F244 V245 S246	H238-T242 PolarHBondContact CE1-OG1 2.86Å; H238-T242 PolarHBondContact ND1-OG1 3.4Å; H238-T242 VanDerWaalsContact O-CB 3.3Å; H238-T242 WeakPolarHBondContact O-CB 3.42Å; H238-T242 PolarHBondContact O-N 3.36Å; H238-T242 PolarHBondContact O-OG1 2.86Å; D239-T242 PolarHBondContact O-N 3.43Å; L240-T242 VanDerWaalsContact C-N 3.34Å; L240-T242 PolarHBondContact O-N 3.42Å; T242-F244 VanDerWaalsContact C-N 3.32Å; T242-V245 PolarHBondContact O-N 2.81Å; T242-S246 WeakPolarHBondContact O-CA 3.3Å; T242-S246 WeakPolarHBondContact O-CB 3.46Å; T242-S246 PolarHBondContact O-N 3.31Å
243	I	69.3	Low	62.1	Low	26 Å²	26	42.7 Å²	42.7	13%	0.133	26%	0.259	C	S	.	.	H	α-helix	trans	-63.5	-41.8	171.2	-71.9	164.8	0	0	0	110	D239 L240 V245 A247 Y252 F255 R341	D239-I243 WeakPolarHBondContact O-CB 3.44Å; D239-I243 WeakPolarHBondContact O-CD1 3.4Å; D239-I243 WeakPolarHBondContact O-CG1 3.36Å; D239-I243 PolarHBondContact O-N 2.7Å; L240-I243 WeakPolarHBondContact O-CB 3.11Å; L240-I243 PolarHBondContact O-N 2.88Å; I243-V245 VanDerWaalsContact C-N 3.26Å; I243-V245 PolarHBondContact O-N 3.15Å; I243-A247 HydrophobicContact CB-CB 4.14Å; I243-A247 HydrophobicContact CG1-CB 4.24Å; I243-A247 HydrophobicContact CG2-CB 3.99Å; I243-A247 WeakPolarHBondContact O-CA 3.36Å; I243-A247 WeakPolarHBondContact O-CB 3.18Å; I243-A247 PolarHBondContact O-N 2.91Å; I243-Y252 HydrophobicContact CG2-CD2 4.39Å; I243-F255 HydrophobicContact CD1-CB 3.95Å; I243-F255 HydrophobicContact CD1-CD2 3.55Å; I243-F255 HydrophobicContact CD1-CE2 4.14Å; I243-F255 HydrophobicContact CD1-CG 3.78Å; I243-R341 PolarHBondContact O-NH2 3.47Å
244	F	63.8	Low	63.3	Low	1 Å²	1	43.5 Å²	43.5	0%	0.004	26%	0.26	C	S	.	.	H	α-helix	trans	-69.3	-16.6	176.4	-93.8	-82.9	0	0	0	114.3	L212 F220 L240 L241 T242 Y252 N273 K276 M277 L280 R341	L212-F244 HydrophobicContact CD2-CD1 4.04Å; L212-F244 HydrophobicContact CD2-CD2 3.67Å; L212-F244 HydrophobicContact CD2-CE1 3.84Å; L212-F244 HydrophobicContact CD2-CE2 3.46Å; L212-F244 VanDerWaalsContact CD2-CE2 3.46Å; L212-F244 HydrophobicContact CD2-CG 3.96Å; L212-F244 HydrophobicContact CD2-CZ 3.56Å; F220-F244 HydrophobicContact CE2-CD1 4.18Å; L240-F244 HydrophobicContact CD1-CD2 4.03Å; L240-F244 HydrophobicContact CD1-CE2 3.84Å; L240-F244 HydrophobicContact CG-CD2 3.95Å; L240-F244 HydrophobicContact CG-CE2 4Å; L240-F244 WeakPolarHBondContact O-CB 3.44Å; L240-F244 VanDerWaalsContact O-CD2 3.27Å; L240-F244 WeakPolarHBondContact O-CD2 3.07Å; L240-F244 PolarHBondContact O-N 3.22Å; L241-F244 CarbonylContact O-C 3.41Å; L241-F244 WeakPolarHBondContact O-CA 3.15Å; L241-F244 WeakPolarHBondContact O-CB 3.06Å; L241-F244 PolarHBondContact O-N 3.5Å; L241-F244 VanDerWaalsContact O-N 3.14Å; T242-F244 VanDerWaalsContact C-N 3.32Å; F244-Y252 HydrophobicContact CE2-CD2 4.05Å; F244-Y252 AromaticContact CE2-CE2 3.7Å; F244-Y252 HydrophobicContact CE2-CE2 3.7Å; F244-Y252 HydrophobicContact CZ-CD2 4.38Å; F244-Y252 AromaticContact CZ-CE2 3.95Å; F244-Y252 HydrophobicContact CZ-CE2 3.95Å; F244-N273 HydrophobicContact CZ-CB 4.35Å; F244-K276 HydrophobicContact CE1-CG 4.31Å; F244-M277 HydrophobicContact CD1-CG 4.24Å; F244-M277 HydrophobicContact CD1-SD 3.63Å; F244-M277 HydrophobicContact CD2-SD 4.47Å; F244-M277 HydrophobicContact CE1-CG 3.61Å; F244-M277 HydrophobicContact CE1-SD 3.65Å; F244-M277 HydrophobicContact CE2-SD 4.49Å; F244-M277 HydrophobicContact CG-SD 4.06Å; F244-M277 HydrophobicContact CZ-CG 3.8Å; F244-M277 HydrophobicContact CZ-SD 4.1Å; F244-L280 HydrophobicContact CD1-CD1 3.68Å; F244-L280 HydrophobicContact CE1-CD1 4.21Å; F244-R341 VanDerWaalsContact O-CZ 3.23Å; F244-R341 PolarHBondContact O-NE 2.88Å; F244-R341 VanDerWaalsContact O-NE 3.1Å; F244-R341 PolarHBondContact O-NH2 3.46Å
245	V	62.4	Low	64	Low	11 Å²	11	41.6 Å²	41.6	7%	0.067	23%	0.233	C	C	.	.	H	α-helix	trans	-102.4	-43.1	174.5	177	0	0	0	0	112.3	F220 L224 L241 T242 I243 R341 T342	F220-V245 HydrophobicContact CB-CG2 3.68Å; L224-V245 HydrophobicContact CD1-CB 3.78Å; L224-V245 HydrophobicContact CD1-CG1 3.48Å; L224-V245 VanDerWaalsContact CD1-CG1 3.48Å; L224-V245 HydrophobicContact CD1-CG2 3.65Å; L224-V245 HydrophobicContact CG-CG2 4.28Å; L241-V245 HydrophobicContact CD2-CG2 4.4Å; L241-V245 WeakPolarHBondContact O-CG2 3.16Å; L241-V245 PolarHBondContact O-N 3.09Å; T242-V245 PolarHBondContact O-N 2.81Å; I243-V245 VanDerWaalsContact C-N 3.26Å; I243-V245 PolarHBondContact O-N 3.15Å; V245-R341 PolarHBondContact O-NE 3.34Å; V245-R341 VanDerWaalsContact O-NE 3.16Å; V245-T342 HydrophobicContact CG1-CG2 3.36Å
246	S	56	Low	64.3	Low	97 Å²	97	41 Å²	41	68%	0.678	23%	0.229	S	C	*	.	H	α-helix	trans	-111.9	-14.9	-165.9	-56.1	0	0	0	0	114.4	T242	T242-S246 WeakPolarHBondContact O-CA 3.3Å; T242-S246 WeakPolarHBondContact O-CB 3.46Å; T242-S246 PolarHBondContact O-N 3.31Å
247	A	58.7	Low	64.6	Low	24 Å²	24	43.8 Å²	43.8	20%	0.198	24%	0.24	C	C	.	.			trans	-112.6	159.6	-171.9	0	0	0	0	0	114.7	I243 A251 R341	I243-A247 HydrophobicContact CB-CB 4.14Å; I243-A247 HydrophobicContact CG1-CB 4.24Å; I243-A247 HydrophobicContact CG2-CB 3.99Å; I243-A247 WeakPolarHBondContact O-CA 3.36Å; I243-A247 WeakPolarHBondContact O-CB 3.18Å; I243-A247 PolarHBondContact O-N 2.91Å; A247-A251 HydrophobicContact CB-CB 3.8Å; A247-R341 PolarHBondContact O-NH2 3.29Å
248	K	60.1	Low	64.9	Low	116 Å²	116	47.8 Å²	47.8	50%	0.504	27%	0.269	S	S	.	.			trans	-83.6	162.8	178.9	-61.9	-170.2	174.7	-160.8	0	112	A250 A251 Y252 E300	K248-A250 PolarHBondContact O-N 2.96Å; K248-A250 VanDerWaalsContact O-N 3.11Å; K248-A251 WeakPolarHBondContact O-CB 3.38Å; K248-A251 PolarHBondContact O-N 2.87Å; K248-Y252 PolarHBondContact O-N 3.22Å; K248-E300 IonicContact NZ-OE1 2.78Å; K248-E300 PolarHBondContact NZ-OE1 2.86Å
249	L	60.1	Low	65	Low	4 Å²	4	48.9 Å²	48.9	2%	0.021	28%	0.276	C	S	.	.	H	α-helix	trans	-50.5	-37	177.5	-165.1	140.3	0	0	0	113.6	A251 Y252 V253 R278	L249-A251 VanDerWaalsContact C-N 3.32Å; L249-A251 PolarHBondContact O-N 3.07Å; L249-Y252 PolarHBondContact O-N 3.17Å; L249-V253 HydrophobicContact CD2-CG2 4.04Å; L249-V253 WeakPolarHBondContact O-CG2 3.37Å; L249-V253 PolarHBondContact O-N 2.86Å; L249-R278 HydrophobicContact CD1-CB 4.18Å; L249-R278 HydrophobicContact CD1-CG 3.29Å
250	A	62.8	Low	64.8	Low	58 Å²	58	50.1 Å²	50.1	48%	0.479	28%	0.278	S	S	.	.	H	α-helix	trans	-63.2	-32.4	176.9	0	0	0	0	0	114.2	K248 K254	K248-A250 PolarHBondContact O-N 2.96Å; K248-A250 VanDerWaalsContact O-N 3.11Å; A250-K254 WeakPolarHBondContact O-CG 3.49Å; A250-K254 PolarHBondContact O-N 3.46Å
251	A	67.6	Low	64.6	Low	38 Å²	38	56.7 Å²	56.7	31%	0.314	31%	0.312	S	S	.	.	H	α-helix	trans	-73.8	-37.1	176.3	0	0	0	0	0	111.2	A247 K248 L249 K254 F255	A247-A251 HydrophobicContact CB-CB 3.8Å; K248-A251 WeakPolarHBondContact O-CB 3.38Å; K248-A251 PolarHBondContact O-N 2.87Å; L249-A251 VanDerWaalsContact C-N 3.32Å; L249-A251 PolarHBondContact O-N 3.07Å; A251-K254 PolarHBondContact O-N 3.26Å; A251-F255 WeakPolarHBondContact O-CB 3.19Å; A251-F255 PolarHBondContact O-N 2.92Å
252	Y	66.6	Low	64.4	Low	1 Å²	1	59.9 Å²	59.9	0%	0.004	33%	0.326	C	S	.	.	H	α-helix	trans	-65.5	-41.3	174.5	179.2	-97.3	0	0	0	112.3	L240 I243 F244 K248 L249 K254 F255 Y256 N273 M274 M277	L240-Y252 HydrophobicContact CD1-CD2 4.15Å; L240-Y252 HydrophobicContact CD1-CE2 3.91Å; I243-Y252 HydrophobicContact CG2-CD2 4.39Å; F244-Y252 HydrophobicContact CE2-CD2 4.05Å; F244-Y252 AromaticContact CE2-CE2 3.7Å; F244-Y252 HydrophobicContact CE2-CE2 3.7Å; F244-Y252 HydrophobicContact CZ-CD2 4.38Å; F244-Y252 AromaticContact CZ-CE2 3.95Å; F244-Y252 HydrophobicContact CZ-CE2 3.95Å; K248-Y252 PolarHBondContact O-N 3.22Å; L249-Y252 PolarHBondContact O-N 3.17Å; Y252-K254 VanDerWaalsContact C-N 3.35Å; Y252-K254 PolarHBondContact O-N 2.85Å; Y252-F255 PolarHBondContact O-N 2.83Å; Y252-Y256 WeakPolarHBondContact O-CB 3.5Å; Y252-Y256 PolarHBondContact O-N 2.9Å; Y252-N273 WeakPolarHBondContact OH-CB 3.16Å; Y252-M274 HydrophobicContact CE1-CG 4.31Å; Y252-M277 HydrophobicContact CD1-CG 4.09Å; Y252-M277 HydrophobicContact CD2-CG 4.02Å; Y252-M277 HydrophobicContact CD2-SD 4.4Å; Y252-M277 HydrophobicContact CE2-CG 4.44Å; Y252-M277 HydrophobicContact CG-CE 4.26Å; Y252-M277 HydrophobicContact CG-CG 3.84Å; Y252-M277 HydrophobicContact CG-SD 4.41Å
253	V	69.3	Low	64.2	Low	37 Å²	37	57.5 Å²	57.5	22%	0.224	31%	0.312	C	S	.	.	H	α-helix	trans	-63.3	-40.9	176.5	174.5	0	0	0	0	111.4	L249 Y256 Q257 M274	L249-V253 HydrophobicContact CD2-CG2 4.04Å; L249-V253 WeakPolarHBondContact O-CG2 3.37Å; L249-V253 PolarHBondContact O-N 2.86Å; V253-Y256 PolarHBondContact O-N 3.07Å; V253-Q257 WeakPolarHBondContact O-CG 3.32Å; V253-Q257 PolarHBondContact O-N 2.96Å; V253-M274 HydrophobicContact CG2-SD 4.49Å
254	K	70.3	Confident	63.8	Low	146 Å²	146	61 Å²	61	64%	0.635	33%	0.331	S	S	*	.	H	α-helix	trans	-63.9	-40.7	174	-72.5	178.8	-179.8	-177.3	0	112	A250 A251 Y252 Q257 S258	A250-K254 WeakPolarHBondContact O-CG 3.49Å; A250-K254 PolarHBondContact O-N 3.46Å; A251-K254 PolarHBondContact O-N 3.26Å; Y252-K254 VanDerWaalsContact C-N 3.35Å; Y252-K254 PolarHBondContact O-N 2.85Å; K254-Q257 PolarHBondContact O-N 2.99Å; K254-S258 PolarHBondContact O-N 2.69Å; K254-S258 PolarHBondContact O-OG 3.36Å
255	F	66.2	Low	63.7	Low	27 Å²	27	66 Å²	66	12%	0.118	37%	0.366	C	S	.	.	H	α-helix	trans	-67.1	-38.4	176.9	-168.3	-90.9	0	0	0	112.4	L236 D239 L240 I243 A251 Y252 S258 N259	L236-F255 HydrophobicContact CB-CZ 4.38Å; L236-F255 HydrophobicContact CD2-CE2 4.39Å; L236-F255 HydrophobicContact CD2-CZ 3.82Å; L236-F255 HydrophobicContact CG-CZ 4.46Å; D239-F255 HydrophobicContact CB-CE2 4.26Å; L240-F255 HydrophobicContact CB-CE1 4.25Å; L240-F255 HydrophobicContact CB-CZ 4.41Å; L240-F255 HydrophobicContact CD1-CD1 3.91Å; L240-F255 HydrophobicContact CD1-CE1 3.83Å; I243-F255 HydrophobicContact CD1-CB 3.95Å; I243-F255 HydrophobicContact CD1-CD2 3.55Å; I243-F255 HydrophobicContact CD1-CE2 4.14Å; I243-F255 HydrophobicContact CD1-CG 3.78Å; A251-F255 WeakPolarHBondContact O-CB 3.19Å; A251-F255 PolarHBondContact O-N 2.92Å; Y252-F255 PolarHBondContact O-N 2.83Å; F255-S258 PolarHBondContact O-N 3.27Å; F255-N259 HydrophobicContact CE1-CB 4.38Å; F255-N259 PolarHBondContact O-N 3.4Å; F255-N259 PolarHBondContact O-ND2 3.15Å
256	Y	66.1	Low	63.4	Low	37 Å²	37	68.1 Å²	68.1	15%	0.145	38%	0.377	C	S	.	.	H	α-helix	trans	-64.5	-39.9	174.6	-173.8	-101.4	0	0	0	111.6	Y252 V253 S258 N259 K260 I263 H270	Y252-Y256 WeakPolarHBondContact O-CB 3.5Å; Y252-Y256 PolarHBondContact O-N 2.9Å; V253-Y256 PolarHBondContact O-N 3.07Å; Y256-S258 VanDerWaalsContact C-N 3.28Å; Y256-S258 PolarHBondContact O-N 2.98Å; Y256-N259 PolarHBondContact O-N 3.37Å; Y256-K260 HydrophobicContact CD1-CG 4.42Å; Y256-K260 HydrophobicContact CE1-CD 4.41Å; Y256-K260 HydrophobicContact CE1-CG 4.18Å; Y256-K260 WeakPolarHBondContact O-CG 3.43Å; Y256-K260 PolarHBondContact O-N 2.97Å; Y256-I263 HydrophobicContact CD2-CD1 3.42Å; Y256-I263 VanDerWaalsContact CD2-CD1 3.42Å; Y256-I263 HydrophobicContact CD2-CG2 4.38Å; Y256-I263 HydrophobicContact CE2-CB 4.19Å; Y256-I263 HydrophobicContact CE2-CD1 3.99Å; Y256-I263 HydrophobicContact CE2-CG2 3.92Å; Y256-I263 HydrophobicContact CG-CD1 4.44Å; Y256-H270 AromaticContact CD1-CE1 3.35Å; Y256-H270 WeakPolarHBondContact CD1-CE1 3.2Å; Y256-H270 AromaticContact CD1-ND1 3.88Å; Y256-H270 AromaticContact CD1-NE2 3.81Å; Y256-H270 AromaticContact CD2-CE1 3.46Å; Y256-H270 VanDerWaalsContact CD2-CE1 3.46Å; Y256-H270 WeakPolarHBondContact CD2-CE1 3.36Å; Y256-H270 AromaticContact CD2-ND1 3.21Å; Y256-H270 WeakPolarHBondContact CD2-ND1 3.25Å; Y256-H270 AromaticContact CE1-CD2 3.93Å; Y256-H270 AromaticContact CE1-CE1 3.46Å; Y256-H270 VanDerWaalsContact CE1-CE1 3.46Å; Y256-H270 WeakPolarHBondContact CE1-CE1 3.11Å; Y256-H270 AromaticContact CE1-CG 3.98Å; Y256-H270 AromaticContact CE1-ND1 3.71Å; Y256-H270 AromaticContact CE1-NE2 3.62Å; Y256-H270 HydrophobicContact CE2-CB 4.04Å; Y256-H270 AromaticContact CE2-CE1 3.64Å; Y256-H270 AromaticContact CE2-CG 3.61Å; Y256-H270 AromaticContact CE2-ND1 3.09Å; Y256-H270 WeakPolarHBondContact CE2-ND1 3.44Å; Y256-H270 AromaticContact CG-CE1 3.36Å; Y256-H270 AromaticContact CG-ND1 3.65Å; Y256-H270 AromaticContact CZ-CD2 3.87Å; Y256-H270 AromaticContact CZ-CE1 3.63Å; Y256-H270 AromaticContact CZ-CG 3.49Å; Y256-H270 VanDerWaalsContact CZ-CG 3.49Å; Y256-H270 AromaticContact CZ-ND1 3.34Å; Y256-H270 VanDerWaalsContact CZ-ND1 3.34Å; Y256-H270 AromaticContact CZ-NE2 3.96Å
257	Q	68.5	Low	63.3	Low	131 Å²	131	66.2 Å²	66.2	61%	0.612	37%	0.372	S	S	*	.	H	α-helix	trans	-63.3	-34.2	176.1	-74.3	174.7	5.4	0	0	112.7	V253 K254	V253-Q257 WeakPolarHBondContact O-CG 3.32Å; V253-Q257 PolarHBondContact O-N 2.96Å; K254-Q257 PolarHBondContact O-N 2.99Å
258	S	69.3	Low	63.3	Low	95 Å²	95	65.4 Å²	65.4	66%	0.664	36%	0.364	S	S	*	.	H	α-helix	trans	-82.2	-24.4	178.9	-59	0	0	0	0	114.3	K254 F255 Y256	K254-S258 PolarHBondContact O-N 2.69Å; K254-S258 PolarHBondContact O-OG 3.36Å; F255-S258 PolarHBondContact O-N 3.27Å; Y256-S258 VanDerWaalsContact C-N 3.28Å; Y256-S258 PolarHBondContact O-N 2.98Å
259	N	64.9	Low	63.1	Low	44 Å²	44	62.1 Å²	62.1	24%	0.235	36%	0.356	C	S	.	.			trans	-135.4	48.2	-169	-60.6	-56.7	0	0	0	113.6	L236 F255 Y256 F262 I263	L236-N259 HydrophobicContact CD2-CB 4.25Å; L236-N259 VanDerWaalsContact CD2-CG 3.41Å; L236-N259 WeakPolarHBondContact CD2-ND2 3.43Å; L236-N259 WeakPolarHBondContact CD2-OD1 3.15Å; F255-N259 HydrophobicContact CE1-CB 4.38Å; F255-N259 PolarHBondContact O-N 3.4Å; F255-N259 PolarHBondContact O-ND2 3.15Å; Y256-N259 PolarHBondContact O-N 3.37Å; N259-F262 HydrophobicContact CB-CB 4.37Å; N259-I263 PolarHBondContact O-N 3.49Å
260	K	61.6	Low	63	Low	103 Å²	103	64.2 Å²	64.2	45%	0.448	37%	0.366	S	S	.	.	H	α-helix	trans	-63.5	-45.5	-179.7	-67.2	-172.5	-180	174.4	0	113.1	Y256 F262 I263 D264	Y256-K260 HydrophobicContact CD1-CG 4.42Å; Y256-K260 HydrophobicContact CE1-CD 4.41Å; Y256-K260 HydrophobicContact CE1-CG 4.18Å; Y256-K260 WeakPolarHBondContact O-CG 3.43Å; Y256-K260 PolarHBondContact O-N 2.97Å; K260-F262 PolarHBondContact O-N 3.22Å; K260-I263 PolarHBondContact O-N 3.06Å; K260-I263 VanDerWaalsContact O-N 3.12Å; K260-D264 PolarHBondContact O-N 3.26Å
261	D	61	Low	63	Low	141 Å²	141	69.2 Å²	69.2	75%	0.754	38%	0.379	S	S	*	.	H	α-helix	trans	-63.1	-31.1	-177.3	-58.1	-60.6	0	0	0	112.5	S265	D261-S265 WeakPolarHBondContact O-CB 3.46Å; D261-S265 PolarHBondContact O-N 2.88Å
262	F	59.7	Low	62.9	Low	70 Å²	70	72.5 Å²	72.5	31%	0.307	39%	0.388	S	S	.	.	H	α-helix	trans	-70.7	-37.5	177.4	-170.6	-108.1	0	0	0	112.1	L236 I237 N259 K260 L266	L236-F262 HydrophobicContact CB-CE1 4.42Å; I237-F262 HydrophobicContact CD1-CE1 4.05Å; I237-F262 HydrophobicContact CD1-CZ 3.57Å; I237-F262 HydrophobicContact CG1-CE1 3.62Å; I237-F262 HydrophobicContact CG1-CZ 3.56Å; N259-F262 HydrophobicContact CB-CB 4.37Å; K260-F262 PolarHBondContact O-N 3.22Å; F262-L266 HydrophobicContact CD1-CD1 3.78Å; F262-L266 HydrophobicContact CE1-CD1 3.5Å; F262-L266 HydrophobicContact CE2-CD1 4.47Å; F262-L266 HydrophobicContact CG-CD1 4.39Å; F262-L266 HydrophobicContact CZ-CD1 3.89Å; F262-L266 VanDerWaalsContact O-CD1 3.29Å; F262-L266 WeakPolarHBondContact O-CD1 3.12Å; F262-L266 WeakPolarHBondContact O-CG 3.04Å; F262-L266 PolarHBondContact O-N 3.32Å
263	I	63.3	Low	62.8	Low	1 Å²	1	72.7 Å²	72.7	1%	0.005	39%	0.389	C	S	.	.	H	α-helix	trans	-78	-38.7	-177.4	-66.9	169.8	0	0	0	110.5	Y256 N259 K260 L266 L268	Y256-I263 HydrophobicContact CD2-CD1 3.42Å; Y256-I263 VanDerWaalsContact CD2-CD1 3.42Å; Y256-I263 HydrophobicContact CD2-CG2 4.38Å; Y256-I263 HydrophobicContact CE2-CB 4.19Å; Y256-I263 HydrophobicContact CE2-CD1 3.99Å; Y256-I263 HydrophobicContact CE2-CG2 3.92Å; Y256-I263 HydrophobicContact CG-CD1 4.44Å; N259-I263 PolarHBondContact O-N 3.49Å; K260-I263 PolarHBondContact O-N 3.06Å; K260-I263 VanDerWaalsContact O-N 3.12Å; I263-L266 PolarHBondContact O-N 2.87Å; I263-L268 HydrophobicContact CG2-CB 4.09Å; I263-L268 PolarHBondContact O-N 2.89Å
264	D	62.2	Low	62.7	Low	100 Å²	100	73 Å²	73	54%	0.535	39%	0.389	S	S	.	.	H	α-helix	trans	-70.3	-38.4	175.1	-73	-21.6	0	0	0	111.7	K260 L266 G267	K260-D264 PolarHBondContact O-N 3.26Å; D264-L266 PolarHBondContact O-N 3.48Å; D264-G267 PolarHBondContact O-N 2.96Å
265	S	60.7	Low	62.5	Low	106 Å²	106	68 Å²	68	74%	0.741	37%	0.374	S	S	*	.	H	α-helix	trans	-64.5	-21.9	174.6	-172.8	0	0	0	0	113.5	D261	D261-S265 WeakPolarHBondContact O-CB 3.46Å; D261-S265 PolarHBondContact O-N 2.88Å
266	L	57.6	Low	62.6	Low	55 Å²	55	67.2 Å²	67.2	29%	0.288	37%	0.371	S	S	.	.	T	Hydrogen-bonded Turn	trans	-88	-3.9	176.8	-72.7	170.3	0	0	0	113.1	V209 F262 I263 D264 L268	V209-L266 HydrophobicContact CG1-CB 4.44Å; V209-L266 HydrophobicContact CG1-CD2 4.4Å; V209-L266 HydrophobicContact CG2-CD1 4.04Å; V209-L266 HydrophobicContact CG2-CD2 3.62Å; V209-L266 HydrophobicContact CG2-CG 4.3Å; F262-L266 HydrophobicContact CD1-CD1 3.78Å; F262-L266 HydrophobicContact CE1-CD1 3.5Å; F262-L266 HydrophobicContact CE2-CD1 4.47Å; F262-L266 HydrophobicContact CG-CD1 4.39Å; F262-L266 HydrophobicContact CZ-CD1 3.89Å; F262-L266 VanDerWaalsContact O-CD1 3.29Å; F262-L266 WeakPolarHBondContact O-CD1 3.12Å; F262-L266 WeakPolarHBondContact O-CG 3.04Å; F262-L266 PolarHBondContact O-N 3.32Å; I263-L266 PolarHBondContact O-N 2.87Å; D264-L266 PolarHBondContact O-N 3.48Å; L266-L268 HydrophobicContact CB-CD1 3.72Å; L266-L268 HydrophobicContact CB-CG 4.2Å; L266-L268 HydrophobicContact CD1-CD1 3.98Å; L266-L268 HydrophobicContact CG-CD1 4.5Å; L266-L268 PolarHBondContact O-N 3.07Å
267	G	52.3	Low	62.7	Low	56 Å²	56	65.5 Å²	65.5	58%	0.577	36%	0.364	S	S	*	.	T	Hydrogen-bonded Turn	trans	63.5	25.3	-178.4	0	0	0	0	0	113.3	D264	D264-G267 PolarHBondContact O-N 2.96Å
268	L	58.5	Low	62.8	Low	7 Å²	7	62.3 Å²	62.3	4%	0.037	35%	0.347	C	S	.	.			trans	-84.6	121.2	178.3	-82.8	157.1	0	0	0	109	V209 L212 I263 L266 H270	V209-L268 HydrophobicContact CG1-CD1 4.31Å; V209-L268 HydrophobicContact CG1-CG 4.35Å; L212-L268 HydrophobicContact CB-CD2 3.67Å; L212-L268 HydrophobicContact CD1-CD1 4.39Å; I263-L268 HydrophobicContact CG2-CB 4.09Å; I263-L268 PolarHBondContact O-N 2.89Å; L266-L268 HydrophobicContact CB-CD1 3.72Å; L266-L268 HydrophobicContact CB-CG 4.2Å; L266-L268 HydrophobicContact CD1-CD1 3.98Å; L266-L268 HydrophobicContact CG-CD1 4.5Å; L266-L268 PolarHBondContact O-N 3.07Å; L268-H270 PolarHBondContact O-N 3.24Å
269	S	55.8	Low	62.9	Low	48 Å²	48	58.2 Å²	58.2	34%	0.336	32%	0.317	S	S	.	.			trans	-70.4	118.3	174.8	72.5	0	0	0	0	109.9	E271 Q272 N273	S269-E271 PolarHBondContact O-N 2.95Å; S269-Q272 PolarHBondContact O-N 3.11Å; S269-Q272 WeakPolarHBondContact OG-CB 3.46Å; S269-Q272 WeakPolarHBondContact OG-CG 3.49Å; S269-Q272 PolarHBondContact OG-N 3.42Å; S269-Q272 PolarHBondContact OG-OE1 2.7Å; S269-Q272 VanDerWaalsContact OG-OE1 3.12Å; S269-N273 PolarHBondContact O-N 3.25Å
270	H	58.3	Low	63	Low	48 Å²	48	56.1 Å²	56.1	22%	0.222	31%	0.306	C	S	.	.	H	α-helix	trans	-56.1	-34.4	178.4	-179.2	58.7	0	0	0	111.7	Y256 L268 N273 M274	Y256-H270 AromaticContact CD1-CE1 3.35Å; Y256-H270 WeakPolarHBondContact CD1-CE1 3.2Å; Y256-H270 AromaticContact CD1-ND1 3.88Å; Y256-H270 AromaticContact CD1-NE2 3.81Å; Y256-H270 AromaticContact CD2-CE1 3.46Å; Y256-H270 VanDerWaalsContact CD2-CE1 3.46Å; Y256-H270 WeakPolarHBondContact CD2-CE1 3.36Å; Y256-H270 AromaticContact CD2-ND1 3.21Å; Y256-H270 WeakPolarHBondContact CD2-ND1 3.25Å; Y256-H270 AromaticContact CE1-CD2 3.93Å; Y256-H270 AromaticContact CE1-CE1 3.46Å; Y256-H270 VanDerWaalsContact CE1-CE1 3.46Å; Y256-H270 WeakPolarHBondContact CE1-CE1 3.11Å; Y256-H270 AromaticContact CE1-CG 3.98Å; Y256-H270 AromaticContact CE1-ND1 3.71Å; Y256-H270 AromaticContact CE1-NE2 3.62Å; Y256-H270 HydrophobicContact CE2-CB 4.04Å; Y256-H270 AromaticContact CE2-CE1 3.64Å; Y256-H270 AromaticContact CE2-CG 3.61Å; Y256-H270 AromaticContact CE2-ND1 3.09Å; Y256-H270 WeakPolarHBondContact CE2-ND1 3.44Å; Y256-H270 AromaticContact CG-CE1 3.36Å; Y256-H270 AromaticContact CG-ND1 3.65Å; Y256-H270 AromaticContact CZ-CD2 3.87Å; Y256-H270 AromaticContact CZ-CE1 3.63Å; Y256-H270 AromaticContact CZ-CG 3.49Å; Y256-H270 VanDerWaalsContact CZ-CG 3.49Å; Y256-H270 AromaticContact CZ-ND1 3.34Å; Y256-H270 VanDerWaalsContact CZ-ND1 3.34Å; Y256-H270 AromaticContact CZ-NE2 3.96Å; L268-H270 PolarHBondContact O-N 3.24Å; H270-N273 PolarHBondContact O-N 2.81Å; H270-M274 VanDerWaalsContact O-CB 3.25Å; H270-M274 WeakPolarHBondContact O-CB 3.47Å; H270-M274 VanDerWaalsContact O-CG 3.27Å; H270-M274 WeakPolarHBondContact O-CG 3.21Å; H270-M274 PolarHBondContact O-N 3.39Å
271	E	64.4	Low	63.4	Low	162 Å²	162	51.6 Å²	51.6	76%	0.757	29%	0.287	S	S	*	.	H	α-helix	trans	-67.5	-42.7	179	-66.1	-175.3	164.3	0	0	113.4	S269 M274 A275	S269-E271 PolarHBondContact O-N 2.95Å; E271-M274 PolarHBondContact O-N 2.9Å; E271-A275 WeakPolarHBondContact O-CB 3.24Å; E271-A275 PolarHBondContact O-N 3.21Å
272	Q	64.3	Low	63.8	Low	108 Å²	108	44.9 Å²	44.9	51%	0.505	25%	0.251	S	S	.	.	H	α-helix	trans	-68.9	-38.3	177	-68.9	171.4	-1.3	0	0	111.1	S269 A275 K276	S269-Q272 PolarHBondContact O-N 3.11Å; S269-Q272 WeakPolarHBondContact OG-CB 3.46Å; S269-Q272 WeakPolarHBondContact OG-CG 3.49Å; S269-Q272 PolarHBondContact OG-N 3.42Å; S269-Q272 PolarHBondContact OG-OE1 2.7Å; S269-Q272 VanDerWaalsContact OG-OE1 3.12Å; Q272-A275 PolarHBondContact O-N 2.93Å; Q272-K276 WeakPolarHBondContact O-CB 3.29Å; Q272-K276 PolarHBondContact O-N 2.87Å
273	N	64.4	Low	64.2	Low	4 Å²	4	41.8 Å²	41.8	2%	0.021	24%	0.238	C	C	.	.	H	α-helix	trans	-68	-37.8	175.6	-71.5	-29.3	0	0	0	112.2	F244 Y252 S269 H270 K276 M277	F244-N273 HydrophobicContact CZ-CB 4.35Å; Y252-N273 WeakPolarHBondContact OH-CB 3.16Å; S269-N273 PolarHBondContact O-N 3.25Å; H270-N273 PolarHBondContact O-N 2.81Å; N273-K276 PolarHBondContact O-N 3.43Å; N273-M277 WeakPolarHBondContact O-CB 3.35Å; N273-M277 WeakPolarHBondContact O-CG 3.18Å; N273-M277 PolarHBondContact O-N 2.83Å
274	M	66.9	Low	64.3	Low	44 Å²	44	43 Å²	43	22%	0.217	25%	0.25	C	C	.	.	H	α-helix	trans	-62.3	-49.1	171.8	-85.4	-93	-111.2	0	0	111.1	Y252 V253 H270 E271 K276 M277 R278	Y252-M274 HydrophobicContact CE1-CG 4.31Å; V253-M274 HydrophobicContact CG2-SD 4.49Å; H270-M274 VanDerWaalsContact O-CB 3.25Å; H270-M274 WeakPolarHBondContact O-CB 3.47Å; H270-M274 VanDerWaalsContact O-CG 3.27Å; H270-M274 WeakPolarHBondContact O-CG 3.21Å; H270-M274 PolarHBondContact O-N 3.39Å; E271-M274 PolarHBondContact O-N 2.9Å; M274-K276 VanDerWaalsContact C-N 3.29Å; M274-K276 PolarHBondContact O-N 3.34Å; M274-M277 PolarHBondContact O-N 3.26Å; M274-R278 WeakPolarHBondContact O-CB 3.42Å; M274-R278 VanDerWaalsContact O-CG 3.26Å; M274-R278 WeakPolarHBondContact O-CG 3.29Å; M274-R278 PolarHBondContact O-N 2.79Å
275	A	67.5	Low	64.5	Low	41 Å²	41	38.7 Å²	38.7	34%	0.339	23%	0.227	S	C	.	.	H	α-helix	trans	-60.5	-39.9	176.3	0	0	0	0	0	111.9	E271 Q272 R278 L279	E271-A275 WeakPolarHBondContact O-CB 3.24Å; E271-A275 PolarHBondContact O-N 3.21Å; Q272-A275 PolarHBondContact O-N 2.93Å; A275-R278 WeakPolarHBondContact O-CB 3.17Å; A275-R278 PolarHBondContact O-N 3.45Å; A275-L279 PolarHBondContact O-N 3.02Å
276	K	68.1	Low	64.7	Low	11 Å²	11	33.8 Å²	33.8	5%	0.048	19%	0.192	C	C	.	.	H	α-helix	trans	-66.5	-44.1	176	-174	163.8	-168.2	172.6	0	112.2	A211 D214 S217 F218 F244 Q272 N273 M274 R278 L279 L280	A211-K276 PolarHBondContact O-NZ 3.45Å; D214-K276 PolarHBondContact O-NZ 3.03Å; S217-K276 WeakPolarHBondContact O-CE 3.11Å; S217-K276 PolarHBondContact O-NZ 3.48Å; F218-K276 HydrophobicContact CD1-CG 4.11Å; F218-K276 HydrophobicContact CE1-CD 4.37Å; F218-K276 HydrophobicContact CE1-CG 3.81Å; F244-K276 HydrophobicContact CE1-CG 4.31Å; Q272-K276 WeakPolarHBondContact O-CB 3.29Å; Q272-K276 PolarHBondContact O-N 2.87Å; N273-K276 PolarHBondContact O-N 3.43Å; M274-K276 VanDerWaalsContact C-N 3.29Å; M274-K276 PolarHBondContact O-N 3.34Å; K276-R278 VanDerWaalsContact C-N 3.35Å; K276-L279 PolarHBondContact O-N 2.89Å; K276-L280 HydrophobicContact CG-CD1 4.12Å; K276-L280 WeakPolarHBondContact O-CB 3.39Å; K276-L280 VanDerWaalsContact O-CG 3.27Å; K276-L280 WeakPolarHBondContact O-CG 3.48Å; K276-L280 PolarHBondContact O-N 2.85Å
277	M	68.3	Low	65	Low	0 Å²	0	33.7 Å²	33.7	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-64.1	-39.3	174.6	-84	-65.9	-60.6	0	0	112.1	F244 Y252 N273 M274 L279 L280 T281	F244-M277 HydrophobicContact CD1-CG 4.24Å; F244-M277 HydrophobicContact CD1-SD 3.63Å; F244-M277 HydrophobicContact CD2-SD 4.47Å; F244-M277 HydrophobicContact CE1-CG 3.61Å; F244-M277 HydrophobicContact CE1-SD 3.65Å; F244-M277 HydrophobicContact CE2-SD 4.49Å; F244-M277 HydrophobicContact CG-SD 4.06Å; F244-M277 HydrophobicContact CZ-CG 3.8Å; F244-M277 HydrophobicContact CZ-SD 4.1Å; Y252-M277 HydrophobicContact CD1-CG 4.09Å; Y252-M277 HydrophobicContact CD2-CG 4.02Å; Y252-M277 HydrophobicContact CD2-SD 4.4Å; Y252-M277 HydrophobicContact CE2-CG 4.44Å; Y252-M277 HydrophobicContact CG-CE 4.26Å; Y252-M277 HydrophobicContact CG-CG 3.84Å; Y252-M277 HydrophobicContact CG-SD 4.41Å; N273-M277 WeakPolarHBondContact O-CB 3.35Å; N273-M277 WeakPolarHBondContact O-CG 3.18Å; N273-M277 PolarHBondContact O-N 2.83Å; M274-M277 PolarHBondContact O-N 3.26Å; M277-L279 VanDerWaalsContact C-N 3.34Å; M277-L280 PolarHBondContact O-N 3.29Å; M277-T281 WeakPolarHBondContact O-CB 3.14Å; M277-T281 PolarHBondContact O-N 2.77Å; M277-T281 PolarHBondContact O-OG1 3.19Å
278	R	70.3	Confident	65.7	Low	64 Å²	64	38.1 Å²	38.1	24%	0.242	20%	0.2	C	C	.	.	H	α-helix	trans	-58.2	-48.9	172.5	-77.2	179.9	174.4	162.1	1.2	110.4	L249 M274 A275 K276 L280 T281 F282 L301 I303 F311	L249-R278 HydrophobicContact CD1-CB 4.18Å; L249-R278 HydrophobicContact CD1-CG 3.29Å; M274-R278 WeakPolarHBondContact O-CB 3.42Å; M274-R278 VanDerWaalsContact O-CG 3.26Å; M274-R278 WeakPolarHBondContact O-CG 3.29Å; M274-R278 PolarHBondContact O-N 2.79Å; A275-R278 WeakPolarHBondContact O-CB 3.17Å; A275-R278 PolarHBondContact O-N 3.45Å; K276-R278 VanDerWaalsContact C-N 3.35Å; R278-L280 PolarHBondContact O-N 2.9Å; R278-T281 PolarHBondContact O-N 3.39Å; R278-F282 WeakPolarHBondContact O-CB 3.31Å; R278-F282 PolarHBondContact O-N 2.99Å; R278-L301 VanDerWaalsContact CA-CD2 3.48Å; R278-L301 HydrophobicContact CB-CD2 3.37Å; R278-L301 HydrophobicContact CG-CD2 3.64Å; R278-L301 PolarHBondContact NE-O 3.35Å; R278-L301 VanDerWaalsContact O-CD2 3.31Å; R278-L301 WeakPolarHBondContact O-CD2 3.42Å; R278-I303 VanDerWaalsContact CZ-CG2 3.42Å; R278-F311 HydrophobicContact CB-CE1 4.15Å; R278-F311 HydrophobicContact CB-CE2 4.01Å; R278-F311 HydrophobicContact CB-CZ 3.48Å; R278-F311 VanDerWaalsContact CB-CZ 3.48Å
279	L	70.6	Confident	65.9	Low	9 Å²	9	43.6 Å²	43.6	5%	0.047	22%	0.223	C	C	.	.	H	α-helix	trans	-63	-43.8	179.1	-171.8	69.2	0	0	0	112.2	F218 A275 K276 M277 T281 F282 M283 F311 A315 T319	F218-L279 HydrophobicContact CD1-CD2 3.97Å; F218-L279 HydrophobicContact CE1-CB 4.48Å; F218-L279 HydrophobicContact CE1-CD2 3.34Å; F218-L279 HydrophobicContact CE1-CG 4.37Å; F218-L279 HydrophobicContact CE2-CD2 4.16Å; F218-L279 HydrophobicContact CZ-CD2 3.42Å; F218-L279 VanDerWaalsContact CZ-CD2 3.42Å; A275-L279 PolarHBondContact O-N 3.02Å; K276-L279 PolarHBondContact O-N 2.89Å; M277-L279 VanDerWaalsContact C-N 3.34Å; L279-T281 PolarHBondContact O-N 3.06Å; L279-F282 WeakPolarHBondContact O-CB 3.32Å; L279-F282 PolarHBondContact O-N 3.45Å; L279-M283 HydrophobicContact CD1-CE 4.32Å; L279-M283 HydrophobicContact CD2-CE 3.76Å; L279-M283 HydrophobicContact CG-CE 3.8Å; L279-M283 HydrophobicContact CG-SD 4.48Å; L279-M283 WeakPolarHBondContact O-CG 3.28Å; L279-M283 PolarHBondContact O-N 2.87Å; L279-F311 HydrophobicContact CB-CZ 4.27Å; L279-A315 HydrophobicContact CD1-CB 3.22Å; L279-T319 HydrophobicContact CD2-CG2 3.78Å
280	L	68	Low	66.3	Low	1 Å²	1	49.1 Å²	49.1	1%	0.005	24%	0.242	C	C	.	.	H	α-helix	trans	-67.5	-34.4	179.2	-72.4	168.5	0	0	0	113	F218 F220 F244 K276 M277 R278 M283 G284 R341	F218-L280 HydrophobicContact CB-CD2 4.18Å; F218-L280 HydrophobicContact CD1-CD2 4.14Å; F218-L280 HydrophobicContact CD1-CG 4.31Å; F220-L280 HydrophobicContact CE2-CD1 4.07Å; F244-L280 HydrophobicContact CD1-CD1 3.68Å; F244-L280 HydrophobicContact CE1-CD1 4.21Å; K276-L280 HydrophobicContact CG-CD1 4.12Å; K276-L280 WeakPolarHBondContact O-CB 3.39Å; K276-L280 VanDerWaalsContact O-CG 3.27Å; K276-L280 WeakPolarHBondContact O-CG 3.48Å; K276-L280 PolarHBondContact O-N 2.85Å; M277-L280 PolarHBondContact O-N 3.29Å; R278-L280 PolarHBondContact O-N 2.9Å; L280-M283 HydrophobicContact CD2-SD 4.32Å; L280-G284 PolarHBondContact O-N 3.13Å; L280-R341 VanDerWaalsContact C-NH1 3.27Å; L280-R341 HydrophobicContact CD2-CG 4.41Å; L280-R341 PolarHBondContact O-NH1 3.47Å
281	T	69.2	Low	67	Low	7 Å²	7	52.2 Å²	52.2	4%	0.043	26%	0.256	C	S	.	.	H	α-helix	trans	-68.9	-42.6	173.9	-53.3	0	0	0	0	109.7	M277 R278 L279 M283 G284 M285 E300	M277-T281 WeakPolarHBondContact O-CB 3.14Å; M277-T281 PolarHBondContact O-N 2.77Å; M277-T281 PolarHBondContact O-OG1 3.19Å; R278-T281 PolarHBondContact O-N 3.39Å; L279-T281 PolarHBondContact O-N 3.06Å; T281-M283 PolarHBondContact O-N 2.84Å; T281-G284 PolarHBondContact O-N 2.96Å; T281-M285 WeakPolarHBondContact O-CG 3.44Å; T281-M285 PolarHBondContact O-N 3.44Å; T281-E300 WeakPolarHBondContact CG2-OE2 3.19Å
282	F	69.6	Low	67.3	Low	0 Å²	0	44.8 Å²	44.8	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-60.8	-42	173.4	-176.5	-104.2	0	0	0	112.4	R278 L279 M285 A286 I292 I297 L301 V312 V322	R278-F282 WeakPolarHBondContact O-CB 3.31Å; R278-F282 PolarHBondContact O-N 2.99Å; L279-F282 WeakPolarHBondContact O-CB 3.32Å; L279-F282 PolarHBondContact O-N 3.45Å; F282-M285 HydrophobicContact CD2-CE 4.29Å; F282-M285 PolarHBondContact O-N 2.81Å; F282-A286 VanDerWaalsContact O-CB 3.24Å; F282-A286 WeakPolarHBondContact O-CB 3.38Å; F282-A286 PolarHBondContact O-N 2.98Å; F282-I292 HydrophobicContact CE2-CD1 3.97Å; F282-I292 HydrophobicContact CZ-CD1 4.42Å; F282-I297 HydrophobicContact CE2-CD1 3.99Å; F282-I297 HydrophobicContact CE2-CG1 4.48Å; F282-L301 HydrophobicContact CD2-CD1 4.4Å; F282-V312 HydrophobicContact CE2-CG2 4.1Å; F282-V312 HydrophobicContact CZ-CG1 4.3Å; F282-V312 HydrophobicContact CZ-CG2 4.09Å; F282-V322 HydrophobicContact CE1-CG1 4.2Å
283	M	67.6	Low	67.9	Low	6 Å²	6	41.6 Å²	41.6	3%	0.03	21%	0.211	C	C	.	.	H	α-helix	trans	-61.7	-42.4	173.7	-73.3	173.8	177.5	0	0	112.3	L279 L280 T281 A286 V287 M321 V322	L279-M283 HydrophobicContact CD1-CE 4.32Å; L279-M283 HydrophobicContact CD2-CE 3.76Å; L279-M283 HydrophobicContact CG-CE 3.8Å; L279-M283 HydrophobicContact CG-SD 4.48Å; L279-M283 WeakPolarHBondContact O-CG 3.28Å; L279-M283 PolarHBondContact O-N 2.87Å; L280-M283 HydrophobicContact CD2-SD 4.32Å; T281-M283 PolarHBondContact O-N 2.84Å; M283-A286 PolarHBondContact O-N 3.04Å; M283-V287 WeakPolarHBondContact O-CG2 3.49Å; M283-V287 PolarHBondContact O-N 2.82Å; M283-M321 HydrophobicContact CE-CB 3.5Å; M283-M321 HydrophobicContact CE-CG 4.22Å; M283-M321 HydrophobicContact CE-SD 3.74Å; M283-V322 HydrophobicContact CE-CG2 4.38Å; M283-V322 HydrophobicContact CG-CG2 3.96Å
284	G	65.2	Low	68.4	Low	25 Å²	25	41.8 Å²	41.8	26%	0.258	21%	0.212	S	C	.	.	H	α-helix	trans	-59.6	-46.9	174.8	0	0	0	0	0	112.2	L280 T281 A286 V287 E288	L280-G284 PolarHBondContact O-N 3.13Å; T281-G284 PolarHBondContact O-N 2.96Å; G284-A286 PolarHBondContact O-N 3.43Å; G284-V287 PolarHBondContact O-N 3.42Å; G284-E288 PolarHBondContact O-N 3.14Å
285	M	67.6	Low	68.7	Low	11 Å²	11	43.4 Å²	43.4	5%	0.054	22%	0.221	C	C	.	.	H	α-helix	trans	-64.4	-38.8	176.3	-68.4	-170.7	-64.4	0	0	112.6	T281 F282 V287 E288 F289 I292 E300 L301	T281-M285 WeakPolarHBondContact O-CG 3.44Å; T281-M285 PolarHBondContact O-N 3.44Å; F282-M285 HydrophobicContact CD2-CE 4.29Å; F282-M285 PolarHBondContact O-N 2.81Å; M285-V287 PolarHBondContact O-N 3.44Å; M285-E288 PolarHBondContact O-N 3.26Å; M285-F289 PolarHBondContact O-N 2.9Å; M285-I292 HydrophobicContact CB-CD1 4.25Å; M285-E300 HydrophobicContact CE-CB 3.98Å; M285-E300 HydrophobicContact SD-CB 3.75Å; M285-E300 HydrophobicContact SD-CG 3.63Å; M285-L301 HydrophobicContact CE-CD1 4.22Å
286	A	64.2	Low	69	Low	2 Å²	2	44.3 Å²	44.3	2%	0.017	22%	0.223	C	C	.	.	H	α-helix	trans	-67.4	-14.8	177.4	0	0	0	0	0	113.8	F282 M283 G284 I292 V335 S338	F282-A286 VanDerWaalsContact O-CB 3.24Å; F282-A286 WeakPolarHBondContact O-CB 3.38Å; F282-A286 PolarHBondContact O-N 2.98Å; M283-A286 PolarHBondContact O-N 3.04Å; G284-A286 PolarHBondContact O-N 3.43Å; A286-I292 HydrophobicContact CB-CD1 4.22Å; A286-V335 HydrophobicContact CB-CG1 4.17Å; A286-V335 HydrophobicContact CB-CG2 3.84Å; A286-S338 PolarHBondContact O-OG 3.23Å; A286-S338 VanDerWaalsContact O-OG 3.08Å
287	V	64.5	Low	69.2	Low	53 Å²	53	43.8 Å²	43.8	32%	0.321	22%	0.221	S	C	.	.	H	α-helix	trans	-89.4	-41.9	172.7	170.3	0	0	0	0	110.9	M283 G284 M285 H340	M283-V287 WeakPolarHBondContact O-CG2 3.49Å; M283-V287 PolarHBondContact O-N 2.82Å; G284-V287 PolarHBondContact O-N 3.42Å; M285-V287 PolarHBondContact O-N 3.44Å; V287-H340 WeakPolarHBondContact CG1-ND1 3.19Å
288	E	65.9	Low	69.4	Low	149 Å²	149	46 Å²	46	70%	0.696	23%	0.231	S	C	*	.	H	α-helix	trans	-73.9	-38.2	179	-68.9	-172.8	144.4	0	0	112.4	G284 M285	G284-E288 PolarHBondContact O-N 3.14Å; M285-E288 PolarHBondContact O-N 3.26Å
289	F	62.7	Low	69.4	Low	122 Å²	122	50.4 Å²	50.4	54%	0.535	25%	0.254	S	S	.	.			trans	-126.4	110.6	-175.2	-57.8	-78.5	0	0	0	110.5	M285 E291 I292	M285-F289 PolarHBondContact O-N 2.9Å; F289-E291 PolarHBondContact O-N 3.26Å; F289-I292 HydrophobicContact CB-CG1 4.4Å; F289-I292 WeakPolarHBondContact O-CG1 3.2Å
290	K	65.8	Low	69.3	Low	165 Å²	165	52.3 Å²	52.3	72%	0.717	26%	0.263	S	S	*	.	S	Bend	trans	-68.8	-20.7	173.7	-68.5	-174.8	179.3	-177.4	0	112.9	V335	K290-V335 PolarHBondContact O-N 3.35Å
291	E	72.2	Confident	69.2	Low	113 Å²	113	52.3 Å²	52.3	53%	0.528	26%	0.263	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.6	120	170.4	-66.7	-174.6	-164.1	0	0	108.9	F289 K332 V334	F289-E291 PolarHBondContact O-N 3.26Å; E291-K332 IonicContact OE2-NZ 2.95Å; E291-K332 PolarHBondContact OE2-NZ 3Å; E291-V334 HydrophobicContact CG-CG2 4.48Å
292	I	71.6	Confident	68.8	Low	6 Å²	6	58.4 Å²	58.4	3%	0.031	29%	0.291	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.8	127	179.5	-40.8	175.2	0	0	0	108.6	F282 M285 A286 F289 I297 K332 V333 V335	F282-I292 HydrophobicContact CE2-CD1 3.97Å; F282-I292 HydrophobicContact CZ-CD1 4.42Å; M285-I292 HydrophobicContact CB-CD1 4.25Å; A286-I292 HydrophobicContact CB-CD1 4.22Å; F289-I292 HydrophobicContact CB-CG1 4.4Å; F289-I292 WeakPolarHBondContact O-CG1 3.2Å; I292-I297 HydrophobicContact CB-CD1 4.07Å; I292-I297 HydrophobicContact CB-CG1 4.29Å; I292-I297 HydrophobicContact CG2-CD1 3.76Å; I292-I297 HydrophobicContact CG2-CG1 3.42Å; I292-I297 VanDerWaalsContact CG2-CG1 3.42Å; I292-K332 CarbonylContact O-C 3.58Å; I292-K332 WeakPolarHBondContact O-CA 3.47Å; I292-V333 PolarHBondContact N-O 2.91Å; I292-V333 PolarHBondContact O-N 2.89Å; I292-V335 HydrophobicContact CD1-CG2 4.16Å; I292-V335 HydrophobicContact CG1-CG2 4.49Å
293	S	76.5	Confident	68.8	Low	41 Å²	41	59.7 Å²	59.7	29%	0.287	30%	0.297	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-78.8	147.3	172.9	62.2	0	0	0	0	111.1	D295 T296 I297	S293-D295 PolarHBondContact O-N 3.23Å; S293-T296 PolarHBondContact O-N 3.24Å; S293-T296 PolarHBondContact OG-OG1 3.29Å; S293-I297 WeakPolarHBondContact O-CG1 3.37Å; S293-I297 PolarHBondContact O-N 3.32Å
294	F	73.4	Confident	68.7	Low	8 Å²	8	61.3 Å²	61.3	4%	0.035	32%	0.316	C	S	.	.	H	α-helix	trans	-58.8	-32.8	178	-86.6	-114.3	0	0	0	112.8	I297 Q298 V308 E309 I326 R331 V333	F294-I297 PolarHBondContact O-N 3.3Å; F294-Q298 VanDerWaalsContact O-CG 3.27Å; F294-Q298 WeakPolarHBondContact O-CG 3.37Å; F294-Q298 PolarHBondContact O-N 3.4Å; F294-V308 HydrophobicContact CD1-CB 4.37Å; F294-V308 HydrophobicContact CD1-CG1 3.85Å; F294-V308 HydrophobicContact CE1-CG1 3.98Å; F294-E309 HydrophobicContact CE1-CG 3.59Å; F294-E309 HydrophobicContact CZ-CG 3.98Å; F294-I326 HydrophobicContact CE2-CG2 4.18Å; F294-I326 HydrophobicContact CZ-CG2 3.87Å; F294-R331 HydrophobicContact CB-CB 4.25Å; F294-R331 HydrophobicContact CD2-CB 4.08Å; F294-R331 VanDerWaalsContact CD2-O 3.22Å; F294-R331 WeakPolarHBondContact CD2-O 3.43Å; F294-R331 HydrophobicContact CG-CB 4.32Å; F294-R331 PolarHBondContact N-O 3.19Å; F294-V333 HydrophobicContact CD2-CG2 4.28Å; F294-V333 HydrophobicContact CE2-CG2 3.79Å; F294-V333 HydrophobicContact CZ-CG2 4.32Å
295	D	74.3	Confident	68.7	Low	77 Å²	77	62.1 Å²	62.1	41%	0.412	32%	0.32	S	S	.	.	H	α-helix	trans	-69.9	-35	-178.7	-51.1	-43	0	0	0	111.7	S293 Q298 Q299 R331	S293-D295 PolarHBondContact O-N 3.23Å; D295-Q298 PolarHBondContact O-N 3.36Å; D295-Q299 WeakPolarHBondContact O-CG 3.28Å; D295-Q299 PolarHBondContact O-N 2.86Å; D295-Q299 VanDerWaalsContact O-N 3.08Å; D295-R331 IonicContact OD1-CZ 3.85Å; D295-R331 IonicContact OD1-NH2 2.95Å; D295-R331 PolarHBondContact OD1-NH2 3.24Å
296	T	74.3	Confident	68.6	Low	61 Å²	61	68.5 Å²	68.5	37%	0.374	35%	0.354	S	S	.	.	H	α-helix	trans	-67.4	-40.5	174.1	-50.9	0	0	0	0	110.6	S293 Q299 E300	S293-T296 PolarHBondContact O-N 3.24Å; S293-T296 PolarHBondContact OG-OG1 3.29Å; T296-Q299 PolarHBondContact O-N 3.09Å; T296-E300 WeakPolarHBondContact O-CB 3.15Å; T296-E300 PolarHBondContact O-N 3.07Å
297	I	71.4	Confident	68.8	Low	0 Å²	0	73.4 Å²	73.4	0%	0	38%	0.38	C	S	.	.	H	α-helix	trans	-63.9	-45	176.6	-64.6	174.3	0	0	0	110.2	F282 I292 S293 F294 Q299 E300 L301 V308 V333	F282-I297 HydrophobicContact CE2-CD1 3.99Å; F282-I297 HydrophobicContact CE2-CG1 4.48Å; I292-I297 HydrophobicContact CB-CD1 4.07Å; I292-I297 HydrophobicContact CB-CG1 4.29Å; I292-I297 HydrophobicContact CG2-CD1 3.76Å; I292-I297 HydrophobicContact CG2-CG1 3.42Å; I292-I297 VanDerWaalsContact CG2-CG1 3.42Å; S293-I297 WeakPolarHBondContact O-CG1 3.37Å; S293-I297 PolarHBondContact O-N 3.32Å; F294-I297 PolarHBondContact O-N 3.3Å; I297-Q299 PolarHBondContact O-N 3.25Å; I297-E300 PolarHBondContact O-N 3.41Å; I297-L301 HydrophobicContact CB-CD1 4.2Å; I297-L301 HydrophobicContact CG2-CD1 3.21Å; I297-L301 VanDerWaalsContact O-CB 3.24Å; I297-L301 WeakPolarHBondContact O-CB 3.41Å; I297-L301 WeakPolarHBondContact O-CD1 3.23Å; I297-L301 PolarHBondContact O-N 3.11Å; I297-V308 HydrophobicContact CB-CG1 4.37Å; I297-V308 HydrophobicContact CG2-CB 4.47Å; I297-V308 HydrophobicContact CG2-CG1 3.52Å; I297-V308 HydrophobicContact CG2-CG2 4.11Å; I297-V333 HydrophobicContact CD1-CB 4.47Å; I297-V333 HydrophobicContact CD1-CG2 4.05Å
298	Q	72.1	Confident	69	Low	47 Å²	47	70.9 Å²	70.9	22%	0.22	37%	0.365	C	S	.	.	H	α-helix	trans	-59.9	-43.9	177.3	-74.5	168.8	15.1	0	0	112.4	F294 D295 Q302 A305 V308	F294-Q298 VanDerWaalsContact O-CG 3.27Å; F294-Q298 WeakPolarHBondContact O-CG 3.37Å; F294-Q298 PolarHBondContact O-N 3.4Å; D295-Q298 PolarHBondContact O-N 3.36Å; Q298-Q302 WeakPolarHBondContact O-CA 3.12Å; Q298-Q302 PolarHBondContact O-N 3.21Å; Q298-A305 VanDerWaalsContact NE2-CA 3.35Å; Q298-V308 HydrophobicContact CG-CG2 3.89Å
299	Q	71.4	Confident	69.1	Low	155 Å²	155	66.5 Å²	66.5	72%	0.724	34%	0.344	S	S	*	.	H	α-helix	trans	-67.7	-42.7	179.9	-72.6	178.9	9.5	0	0	112.7	D295 T296 I297	D295-Q299 WeakPolarHBondContact O-CG 3.28Å; D295-Q299 PolarHBondContact O-N 2.86Å; D295-Q299 VanDerWaalsContact O-N 3.08Å; T296-Q299 PolarHBondContact O-N 3.09Å; I297-Q299 PolarHBondContact O-N 3.25Å
300	E	67.5	Low	69.5	Low	50 Å²	50	63.5 Å²	63.5	23%	0.234	34%	0.342	C	S	.	.	H	α-helix	trans	-77.2	-32.6	-178.1	-78.6	-102.5	166.5	0	0	112.9	K248 T281 M285 T296 I297	K248-E300 IonicContact NZ-OE1 2.78Å; K248-E300 PolarHBondContact NZ-OE1 2.86Å; T281-E300 WeakPolarHBondContact CG2-OE2 3.19Å; M285-E300 HydrophobicContact CE-CB 3.98Å; M285-E300 HydrophobicContact SD-CB 3.75Å; M285-E300 HydrophobicContact SD-CG 3.63Å; T296-E300 WeakPolarHBondContact O-CB 3.15Å; T296-E300 PolarHBondContact O-N 3.07Å; I297-E300 PolarHBondContact O-N 3.41Å
301	L	66.7	Low	69.7	Low	0 Å²	0	57.2 Å²	57.2	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-98.4	-13.3	-176.4	-69.7	145	0	0	0	114.4	R278 F282 M285 I297 I303 F311	R278-L301 VanDerWaalsContact CA-CD2 3.48Å; R278-L301 HydrophobicContact CB-CD2 3.37Å; R278-L301 HydrophobicContact CG-CD2 3.64Å; R278-L301 PolarHBondContact NE-O 3.35Å; R278-L301 VanDerWaalsContact O-CD2 3.31Å; R278-L301 WeakPolarHBondContact O-CD2 3.42Å; F282-L301 HydrophobicContact CD2-CD1 4.4Å; M285-L301 HydrophobicContact CE-CD1 4.22Å; I297-L301 HydrophobicContact CB-CD1 4.2Å; I297-L301 HydrophobicContact CG2-CD1 3.21Å; I297-L301 VanDerWaalsContact O-CB 3.24Å; I297-L301 WeakPolarHBondContact O-CB 3.41Å; I297-L301 WeakPolarHBondContact O-CD1 3.23Å; I297-L301 PolarHBondContact O-N 3.11Å; L301-I303 VanDerWaalsContact C-N 3.33Å; L301-I303 HydrophobicContact CB-CD1 4.07Å; L301-I303 HydrophobicContact CB-CG1 3.85Å; L301-I303 PolarHBondContact O-N 3.3Å; L301-F311 HydrophobicContact CD2-CE1 4.1Å
302	Q	61.2	Low	69.5	Low	136 Å²	136	51.9 Å²	51.9	64%	0.636	29%	0.29	S	S	*	.	T	Hydrogen-bonded Turn	trans	50.8	49.1	-178.3	-59.9	-175.7	-11.6	0	0	112.6	Q298	Q298-Q302 WeakPolarHBondContact O-CA 3.12Å; Q298-Q302 PolarHBondContact O-N 3.21Å
303	I	68.2	Low	69.4	Low	27 Å²	27	55.9 Å²	55.9	14%	0.138	31%	0.311	C	S	.	.			trans	-123.4	154.8	177.6	52.9	174.9	0	0	0	110.5	R278 L301 V308 F311	R278-I303 VanDerWaalsContact CZ-CG2 3.42Å; L301-I303 VanDerWaalsContact C-N 3.33Å; L301-I303 HydrophobicContact CB-CD1 4.07Å; L301-I303 HydrophobicContact CB-CG1 3.85Å; L301-I303 PolarHBondContact O-N 3.3Å; I303-V308 HydrophobicContact CD1-CB 4.27Å; I303-V308 HydrophobicContact CD1-CG2 3.65Å; I303-V308 HydrophobicContact CG1-CG2 3.66Å; I303-F311 HydrophobicContact CD1-CB 4.16Å; I303-F311 HydrophobicContact CD1-CG 4.39Å
304	G	66.9	Low	68.8	Low	40 Å²	40	56.5 Å²	56.5	41%	0.412	31%	0.311	S	S	.	.			trans	-62.2	150	175.6	0	0	0	0	0	111.4	D306 D307 V308	G304-D306 PolarHBondContact O-N 3.38Å; G304-D306 VanDerWaalsContact O-N 3.16Å; G304-D307 PolarHBondContact O-N 2.85Å; G304-V308 WeakPolarHBondContact O-CG2 3.46Å; G304-V308 PolarHBondContact O-N 2.8Å
305	A	63.6	Low	68.2	Low	42 Å²	42	56.2 Å²	56.2	35%	0.347	31%	0.31	S	S	.	.	H	α-helix	trans	-54.5	-35.4	-177.2	0	0	0	0	0	113.4	Q298	Q298-A305 VanDerWaalsContact NE2-CA 3.35Å
306	D	65.7	Low	67.3	Low	144 Å²	144	53.5 Å²	53.5	77%	0.77	30%	0.298	S	S	*	.	H	α-helix	trans	-76.5	-30.8	-178.8	-55.6	-53.5	0	0	0	112.4	G304 V308	G304-D306 PolarHBondContact O-N 3.38Å; G304-D306 VanDerWaalsContact O-N 3.16Å; D306-V308 VanDerWaalsContact C-N 3.33Å
307	D	68.4	Low	66.4	Low	105 Å²	105	55.6 Å²	55.6	56%	0.561	31%	0.31	S	S	*	.	H	α-helix	trans	-78.9	-19	178	-67.3	-31.6	0	0	0	112.4	G304 E309 F311	G304-D307 PolarHBondContact O-N 2.85Å; D307-E309 VanDerWaalsContact C-N 3.33Å; D307-E309 PolarHBondContact O-N 3.36Å; D307-F311 WeakPolarHBondContact O-CB 3.43Å; D307-F311 PolarHBondContact O-N 2.86Å
308	V	68.7	Low	65.7	Low	0 Å²	0	64.1 Å²	64.1	0%	0	34%	0.343	C	S	.	.	H	α-helix	trans	-60.2	-44.1	175.7	170.5	0	0	0	0	110.8	F294 I297 Q298 I303 G304 D306 F311 V312	F294-V308 HydrophobicContact CD1-CB 4.37Å; F294-V308 HydrophobicContact CD1-CG1 3.85Å; F294-V308 HydrophobicContact CE1-CG1 3.98Å; I297-V308 HydrophobicContact CB-CG1 4.37Å; I297-V308 HydrophobicContact CG2-CB 4.47Å; I297-V308 HydrophobicContact CG2-CG1 3.52Å; I297-V308 HydrophobicContact CG2-CG2 4.11Å; Q298-V308 HydrophobicContact CG-CG2 3.89Å; I303-V308 HydrophobicContact CD1-CB 4.27Å; I303-V308 HydrophobicContact CD1-CG2 3.65Å; I303-V308 HydrophobicContact CG1-CG2 3.66Å; G304-V308 WeakPolarHBondContact O-CG2 3.46Å; G304-V308 PolarHBondContact O-N 2.8Å; D306-V308 VanDerWaalsContact C-N 3.33Å; V308-F311 PolarHBondContact O-N 3.16Å; V308-V312 HydrophobicContact CG1-CG2 4.16Å; V308-V312 WeakPolarHBondContact O-CB 3.18Å; V308-V312 WeakPolarHBondContact O-CG2 3.4Å; V308-V312 PolarHBondContact O-N 2.84Å
309	E	69.6	Low	65.1	Low	57 Å²	57	62.9 Å²	62.9	27%	0.266	34%	0.338	S	S	.	.	H	α-helix	trans	-66.4	-47.5	-178.7	-65.6	-169.8	165	0	0	111.2	F294 D307 F311 V312 I313 Q328	F294-E309 HydrophobicContact CE1-CG 3.59Å; F294-E309 HydrophobicContact CZ-CG 3.98Å; D307-E309 VanDerWaalsContact C-N 3.33Å; D307-E309 PolarHBondContact O-N 3.36Å; E309-F311 VanDerWaalsContact C-N 3.26Å; E309-F311 PolarHBondContact O-N 3.5Å; E309-V312 PolarHBondContact O-N 3.15Å; E309-I313 WeakPolarHBondContact O-CB 3.37Å; E309-I313 VanDerWaalsContact O-CG1 3.23Å; E309-I313 WeakPolarHBondContact O-CG1 3.19Å; E309-I313 PolarHBondContact O-N 3.25Å; E309-Q328 PolarHBondContact OE1-NE2 3Å; E309-Q328 PolarHBondContact OE2-NE2 3.17Å
310	A	71.2	Confident	64.6	Low	59 Å²	59	63.1 Å²	63.1	49%	0.488	34%	0.337	S	S	.	.	H	α-helix	trans	-59	-40.4	176	0	0	0	0	0	111.4	D314	A310-D314 VanDerWaalsContact O-CB 3.28Å; A310-D314 WeakPolarHBondContact O-CB 3.49Å; A310-D314 PolarHBondContact O-N 2.74Å
311	F	68.9	Low	63.9	Low	33 Å²	33	62.8 Å²	62.8	15%	0.145	34%	0.336	C	S	.	.	H	α-helix	trans	-68.4	-42.7	176.9	-173.2	-96.3	0	0	0	112.5	R278 L279 L301 I303 D307 V308 E309 I313 D314 A315	R278-F311 HydrophobicContact CB-CE1 4.15Å; R278-F311 HydrophobicContact CB-CE2 4.01Å; R278-F311 HydrophobicContact CB-CZ 3.48Å; R278-F311 VanDerWaalsContact CB-CZ 3.48Å; L279-F311 HydrophobicContact CB-CZ 4.27Å; L301-F311 HydrophobicContact CD2-CE1 4.1Å; I303-F311 HydrophobicContact CD1-CB 4.16Å; I303-F311 HydrophobicContact CD1-CG 4.39Å; D307-F311 WeakPolarHBondContact O-CB 3.43Å; D307-F311 PolarHBondContact O-N 2.86Å; V308-F311 PolarHBondContact O-N 3.16Å; E309-F311 VanDerWaalsContact C-N 3.26Å; E309-F311 PolarHBondContact O-N 3.5Å; F311-I313 VanDerWaalsContact C-N 3.34Å; F311-D314 PolarHBondContact O-N 3.43Å; F311-A315 HydrophobicContact CE1-CB 4.47Å; F311-A315 WeakPolarHBondContact O-CB 3.44Å; F311-A315 PolarHBondContact O-N 3.28Å
312	V	68.1	Low	63.8	Low	1 Å²	1	62.8 Å²	62.8	1%	0.006	34%	0.336	C	S	.	.	H	α-helix	trans	-66.3	-38.8	177.8	172.6	0	0	0	0	110.6	F282 V308 E309 A316 C324 I326 V333	F282-V312 HydrophobicContact CE2-CG2 4.1Å; F282-V312 HydrophobicContact CZ-CG1 4.3Å; F282-V312 HydrophobicContact CZ-CG2 4.09Å; V308-V312 HydrophobicContact CG1-CG2 4.16Å; V308-V312 WeakPolarHBondContact O-CB 3.18Å; V308-V312 WeakPolarHBondContact O-CG2 3.4Å; V308-V312 PolarHBondContact O-N 2.84Å; E309-V312 PolarHBondContact O-N 3.15Å; V312-A316 WeakPolarHBondContact O-CB 3.21Å; V312-A316 PolarHBondContact O-N 2.91Å; V312-C324 VanDerWaalsContact CG1-SG 3.55Å; V312-I326 HydrophobicContact CB-CD1 4.35Å; V312-I326 HydrophobicContact CG1-CD1 3.89Å; V312-I326 HydrophobicContact CG1-CG1 4.16Å; V312-V333 HydrophobicContact CG1-CG1 4.23Å
313	I	69.3	Low	64	Low	91 Å²	91	63.3 Å²	63.3	47%	0.467	33%	0.333	S	S	.	.	H	α-helix	trans	-65.9	-48.4	175.2	-67.5	166.8	0	0	0	110.3	E309 F311 A315 A316 V317 I326	E309-I313 WeakPolarHBondContact O-CB 3.37Å; E309-I313 VanDerWaalsContact O-CG1 3.23Å; E309-I313 WeakPolarHBondContact O-CG1 3.19Å; E309-I313 PolarHBondContact O-N 3.25Å; F311-I313 VanDerWaalsContact C-N 3.34Å; I313-A315 PolarHBondContact O-N 3.29Å; I313-A316 PolarHBondContact O-N 2.93Å; I313-V317 HydrophobicContact CG2-CG2 4.04Å; I313-V317 WeakPolarHBondContact O-CB 3.37Å; I313-V317 VanDerWaalsContact O-CG2 3.22Å; I313-V317 WeakPolarHBondContact O-CG2 3.43Å; I313-V317 PolarHBondContact O-N 2.84Å; I313-I326 HydrophobicContact CG1-CD1 4.08Å
314	D	64.9	Low	64.1	Low	54 Å²	54	63.3 Å²	63.3	29%	0.289	34%	0.335	S	S	.	.	H	α-helix	trans	-63.4	-42.6	177.9	-175	62.1	0	0	0	111.5	A310 F311 A316 R318	A310-D314 VanDerWaalsContact O-CB 3.28Å; A310-D314 WeakPolarHBondContact O-CB 3.49Å; A310-D314 PolarHBondContact O-N 2.74Å; F311-D314 PolarHBondContact O-N 3.43Å; D314-A316 PolarHBondContact O-N 2.89Å; D314-R318 VanDerWaalsContact CG-CZ 3.44Å; D314-R318 WeakPolarHBondContact O-CA 3.23Å; D314-R318 WeakPolarHBondContact O-CB 3.49Å; D314-R318 PolarHBondContact O-N 2.84Å; D314-R318 WeakPolarHBondContact OD1-CD 3.33Å; D314-R318 IonicContact OD1-CZ 2.9Å; D314-R318 IonicContact OD1-NE 3.38Å; D314-R318 PolarHBondContact OD1-NE 2.88Å; D314-R318 IonicContact OD1-NH1 2.74Å; D314-R318 PolarHBondContact OD1-NH1 3.42Å; D314-R318 IonicContact OD1-NH2 3.43Å; D314-R318 IonicContact OD2-CZ 3.4Å; D314-R318 IonicContact OD2-NE 3.79Å; D314-R318 PolarHBondContact OD2-NE 3.24Å; D314-R318 IonicContact OD2-NH1 3.3Å; D314-R318 PolarHBondContact OD2-NH1 3.5Å; D314-R318 IonicContact OD2-NH2 3.2Å; D314-R318 PolarHBondContact OD2-NH2 3.22Å
315	A	60.1	Low	64.3	Low	2 Å²	2	68.6 Å²	68.6	2%	0.017	35%	0.347	C	S	.	.	H	α-helix	trans	-60.3	-44.3	174.3	0	0	0	0	0	113.3	L279 F311 I313 T319	L279-A315 HydrophobicContact CD1-CB 3.22Å; F311-A315 HydrophobicContact CE1-CB 4.47Å; F311-A315 WeakPolarHBondContact O-CB 3.44Å; F311-A315 PolarHBondContact O-N 3.28Å; I313-A315 PolarHBondContact O-N 3.29Å; A315-T319 WeakPolarHBondContact O-CB 3.27Å; A315-T319 PolarHBondContact O-OG1 3.11Å
316	A	56.3	Low	64.8	Low	19 Å²	19	69.6 Å²	69.6	16%	0.157	35%	0.345	C	S	.	.	H	α-helix	trans	-77.1	-44.5	-178	0	0	0	0	0	112.1	V312 I313 D314 K320 V322	V312-A316 WeakPolarHBondContact O-CB 3.21Å; V312-A316 PolarHBondContact O-N 2.91Å; I313-A316 PolarHBondContact O-N 2.93Å; D314-A316 PolarHBondContact O-N 2.89Å; A316-K320 PolarHBondContact O-N 3.47Å; A316-V322 WeakPolarHBondContact CA-O 3.08Å; A316-V322 WeakPolarHBondContact CB-O 3.48Å
317	V	54.8	Low	65.3	Low	106 Å²	106	65 Å²	65	64%	0.642	32%	0.321	S	S	*	.	H	α-helix	trans	-84.5	-46.1	-171.4	178.8	0	0	0	0	111.9	I313	I313-V317 HydrophobicContact CG2-CG2 4.04Å; I313-V317 WeakPolarHBondContact O-CB 3.37Å; I313-V317 VanDerWaalsContact O-CG2 3.22Å; I313-V317 WeakPolarHBondContact O-CG2 3.43Å; I313-V317 PolarHBondContact O-N 2.84Å
318	R	56.5	Low	65.4	Low	179 Å²	179	66.1 Å²	66.1	68%	0.675	32%	0.323	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.2	-40	-175.8	-166.3	172.4	65.8	-173.7	-2	111.6	D314	D314-R318 VanDerWaalsContact CG-CZ 3.44Å; D314-R318 WeakPolarHBondContact O-CA 3.23Å; D314-R318 WeakPolarHBondContact O-CB 3.49Å; D314-R318 PolarHBondContact O-N 2.84Å; D314-R318 WeakPolarHBondContact OD1-CD 3.33Å; D314-R318 IonicContact OD1-CZ 2.9Å; D314-R318 IonicContact OD1-NE 3.38Å; D314-R318 PolarHBondContact OD1-NE 2.88Å; D314-R318 IonicContact OD1-NH1 2.74Å; D314-R318 PolarHBondContact OD1-NH1 3.42Å; D314-R318 IonicContact OD1-NH2 3.43Å; D314-R318 IonicContact OD2-CZ 3.4Å; D314-R318 IonicContact OD2-NE 3.79Å; D314-R318 PolarHBondContact OD2-NE 3.24Å; D314-R318 IonicContact OD2-NH1 3.3Å; D314-R318 PolarHBondContact OD2-NH1 3.5Å; D314-R318 IonicContact OD2-NH2 3.2Å; D314-R318 PolarHBondContact OD2-NH2 3.22Å
319	T	59.5	Low	65.6	Low	20 Å²	20	72.7 Å²	72.7	12%	0.123	36%	0.363	C	S	.	.	T	Hydrogen-bonded Turn	trans	-89	-16.3	-174.6	-3.4	0	0	0	0	113.7	F218 L279 A315 M321	F218-T319 HydrophobicContact CD2-CG2 4.02Å; F218-T319 HydrophobicContact CE2-CG2 3.22Å; F218-T319 HydrophobicContact CZ-CG2 3.65Å; L279-T319 HydrophobicContact CD2-CG2 3.78Å; A315-T319 WeakPolarHBondContact O-CB 3.27Å; A315-T319 PolarHBondContact O-OG1 3.11Å; T319-M321 HydrophobicContact CG2-SD 4.3Å; T319-M321 VanDerWaalsContact O-CG 3.31Å; T319-M321 WeakPolarHBondContact O-CG 3.15Å; T319-M321 PolarHBondContact O-N 3.41Å
320	K	59.7	Low	65.7	Low	160 Å²	160	75.7 Å²	75.7	70%	0.696	38%	0.377	S	S	*	.			trans	52.3	8.5	-176.1	-64.4	-175.1	178.1	-180	0	115.7	A316	A316-K320 PolarHBondContact O-N 3.47Å
321	M	54.2	Low	65.7	Low	43 Å²	43	78.8 Å²	78.8	21%	0.212	38%	0.376	C	S	.	.	S	Bend	trans	-93	-13.9	-172.2	-76.2	178.2	-166.8	0	0	113.4	F218 M283 T319 T339	F218-M321 HydrophobicContact CB-CE 4.48Å; F218-M321 HydrophobicContact CB-SD 3.95Å; F218-M321 HydrophobicContact CD2-CE 3.59Å; F218-M321 HydrophobicContact CD2-SD 3.53Å; F218-M321 VanDerWaalsContact CD2-SD 3.53Å; F218-M321 HydrophobicContact CE2-CE 4.32Å; F218-M321 HydrophobicContact CE2-SD 4.32Å; F218-M321 HydrophobicContact CG-CE 4.47Å; F218-M321 HydrophobicContact CG-SD 4Å; M283-M321 HydrophobicContact CE-CB 3.5Å; M283-M321 HydrophobicContact CE-CG 4.22Å; M283-M321 HydrophobicContact CE-SD 3.74Å; T319-M321 HydrophobicContact CG2-SD 4.3Å; T319-M321 VanDerWaalsContact O-CG 3.31Å; T319-M321 WeakPolarHBondContact O-CG 3.15Å; T319-M321 PolarHBondContact O-N 3.41Å; M321-T339 PolarHBondContact O-N 2.91Å; M321-T339 PolarHBondContact O-OG1 3.1Å; M321-T339 VanDerWaalsContact O-OG1 3.07Å
322	V	63.7	Low	66.1	Low	1 Å²	1	80.3 Å²	80.3	1%	0.006	38%	0.383	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-135.2	120.6	177.3	-174.3	0	0	0	0	109	F282 M283 A316 C324 V335 H337	F282-V322 HydrophobicContact CE1-CG1 4.2Å; M283-V322 HydrophobicContact CE-CG2 4.38Å; M283-V322 HydrophobicContact CG-CG2 3.96Å; A316-V322 WeakPolarHBondContact CA-O 3.08Å; A316-V322 WeakPolarHBondContact CB-O 3.48Å; V322-C324 HydrophobicContact CG1-CB 4.4Å; V322-V335 HydrophobicContact CG1-CG1 4.07Å; V322-H337 WeakPolarHBondContact CA-O 3.43Å
323	Y	66.8	Low	66.2	Low	146 Å²	146	80.3 Å²	80.3	57%	0.573	38%	0.383	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-95.9	109	167.6	-74.7	-86.9	0	0	0	108.1	S336 H337	Y323-S336 WeakPolarHBondContact O-CA 3.44Å; Y323-S336 WeakPolarHBondContact O-CB 3.15Å; Y323-S336 PolarHBondContact O-N 2.9Å; Y323-H337 PolarHBondContact N-O 3.48Å; Y323-H337 PolarHBondContact O-N 3.43Å
324	C	68.7	Low	66.3	Low	27 Å²	27	78.7 Å²	78.7	18%	0.182	38%	0.377	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.1	153.1	174.5	61	0	0	0	0	111.1	V312 V322 V333 V334 V335	V312-C324 VanDerWaalsContact CG1-SG 3.55Å; V322-C324 HydrophobicContact CG1-CB 4.4Å; C324-V333 HydrophobicContact CB-CG1 3.6Å; C324-V334 CarbonylContact C-O 3.5Å; C324-V334 VanDerWaalsContact CA-O 3.26Å; C324-V334 WeakPolarHBondContact CA-O 3.41Å; C324-V335 HydrophobicContact CB-CG2 4.43Å
325	K	71.6	Confident	66.5	Low	151 Å²	151	76.6 Å²	76.6	66%	0.657	37%	0.366	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-111.5	130.5	169.1	-66.2	-176.7	-179.6	179.4	0	107.3	V334	K325-V334 PolarHBondContact N-O 3.48Å; K325-V334 PolarHBondContact O-N 2.82Å
326	I	75.1	Confident	66.6	Low	63 Å²	63	79.2 Å²	79.2	32%	0.323	38%	0.384	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.5	124.3	177.8	-57.8	176.6	0	0	0	107.5	F294 V312 I313 V333	F294-I326 HydrophobicContact CE2-CG2 4.18Å; F294-I326 HydrophobicContact CZ-CG2 3.87Å; V312-I326 HydrophobicContact CB-CD1 4.35Å; V312-I326 HydrophobicContact CG1-CD1 3.89Å; V312-I326 HydrophobicContact CG1-CG1 4.16Å; I313-I326 HydrophobicContact CG1-CD1 4.08Å; I326-V333 HydrophobicContact CG1-CG2 4.41Å
327	D	75.2	Confident	66.8	Low	49 Å²	49	85.1 Å²	85.1	26%	0.262	41%	0.408	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.7	97.5	166.8	-171.4	-29.1	0	0	0	108.1	T329 Q330 R331 K332	D327-T329 VanDerWaalsContact C-N 3.34Å; D327-T329 PolarHBondContact OD1-N 2.92Å; D327-T329 VanDerWaalsContact OD1-N 3.16Å; D327-T329 PolarHBondContact OD1-OG1 3.28Å; D327-Q330 PolarHBondContact OD1-N 2.76Å; D327-R331 PolarHBondContact O-N 3.35Å; D327-R331 VanDerWaalsContact O-N 3.13Å; D327-K332 CarbonylContact C-O 3.59Å; D327-K332 WeakPolarHBondContact CA-O 3.4Å; D327-K332 PolarHBondContact N-O 3.26Å; D327-K332 PolarHBondContact O-N 2.88Å
328	Q	71.6	Confident	67	Low	128 Å²	128	81.4 Å²	81.4	60%	0.598	39%	0.387	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.8	-31.6	-176.2	-162.9	166.3	32.3	0	0	111.9	E309 R331	E309-Q328 PolarHBondContact OE1-NE2 3Å; E309-Q328 PolarHBondContact OE2-NE2 3.17Å; Q328-R331 PolarHBondContact O-N 2.95Å
329	T	72.9	Confident	67.1	Low	137 Å²	137	76 Å²	76	84%	0.84	37%	0.374	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.5	-37.7	178.9	35.4	0	0	0	0	112.8	D327	D327-T329 VanDerWaalsContact C-N 3.34Å; D327-T329 PolarHBondContact OD1-N 2.92Å; D327-T329 VanDerWaalsContact OD1-N 3.16Å; D327-T329 PolarHBondContact OD1-OG1 3.28Å
330	Q	71.2	Confident	67	Low	120 Å²	120	77.9 Å²	77.9	56%	0.561	38%	0.381	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91.5	-2.5	177.6	-61.6	-168.9	-0.1	0	0	113.4	D327 K332	D327-Q330 PolarHBondContact OD1-N 2.76Å; Q330-K332 VanDerWaalsContact C-N 3.26Å; Q330-K332 HydrophobicContact CB-CB 4.38Å; Q330-K332 HydrophobicContact CB-CD 4.27Å; Q330-K332 HydrophobicContact CB-CG 4.25Å; Q330-K332 PolarHBondContact O-N 3.3Å
331	R	71.4	Confident	66.9	Low	124 Å²	124	71.8 Å²	71.8	47%	0.468	35%	0.354	S	S	.	.	T	Hydrogen-bonded Turn	trans	48.8	51.2	-170.3	-66	177.7	62.7	157.2	-8.5	110.9	F294 D295 D327 Q328	F294-R331 HydrophobicContact CB-CB 4.25Å; F294-R331 HydrophobicContact CD2-CB 4.08Å; F294-R331 VanDerWaalsContact CD2-O 3.22Å; F294-R331 WeakPolarHBondContact CD2-O 3.43Å; F294-R331 HydrophobicContact CG-CB 4.32Å; F294-R331 PolarHBondContact N-O 3.19Å; D295-R331 IonicContact OD1-CZ 3.85Å; D295-R331 IonicContact OD1-NH2 2.95Å; D295-R331 PolarHBondContact OD1-NH2 3.24Å; D327-R331 PolarHBondContact O-N 3.35Å; D327-R331 VanDerWaalsContact O-N 3.13Å; Q328-R331 PolarHBondContact O-N 2.95Å
332	K	75.7	Confident	66.8	Low	66 Å²	66	72.5 Å²	72.5	29%	0.287	36%	0.361	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.6	147.3	178.4	-73	-177.4	174.4	-166.8	0	111.7	E291 I292 D327 Q330	E291-K332 IonicContact OE2-NZ 2.95Å; E291-K332 PolarHBondContact OE2-NZ 3Å; I292-K332 CarbonylContact O-C 3.58Å; I292-K332 WeakPolarHBondContact O-CA 3.47Å; D327-K332 CarbonylContact C-O 3.59Å; D327-K332 WeakPolarHBondContact CA-O 3.4Å; D327-K332 PolarHBondContact N-O 3.26Å; D327-K332 PolarHBondContact O-N 2.88Å; Q330-K332 VanDerWaalsContact C-N 3.26Å; Q330-K332 HydrophobicContact CB-CB 4.38Å; Q330-K332 HydrophobicContact CB-CD 4.27Å; Q330-K332 HydrophobicContact CB-CG 4.25Å; Q330-K332 PolarHBondContact O-N 3.3Å
333	V	71.3	Confident	66.4	Low	0 Å²	0	76.5 Å²	76.5	0%	0	38%	0.378	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-113.2	118.9	170	-178.4	0	0	0	0	107.6	I292 F294 I297 V312 C324 I326	I292-V333 PolarHBondContact N-O 2.91Å; I292-V333 PolarHBondContact O-N 2.89Å; F294-V333 HydrophobicContact CD2-CG2 4.28Å; F294-V333 HydrophobicContact CE2-CG2 3.79Å; F294-V333 HydrophobicContact CZ-CG2 4.32Å; I297-V333 HydrophobicContact CD1-CB 4.47Å; I297-V333 HydrophobicContact CD1-CG2 4.05Å; V312-V333 HydrophobicContact CG1-CG1 4.23Å; C324-V333 HydrophobicContact CB-CG1 3.6Å; I326-V333 HydrophobicContact CG1-CG2 4.41Å
334	V	70.8	Confident	66.3	Low	57 Å²	57	71 Å²	71	35%	0.345	37%	0.366	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.6	116.9	177.8	-175	0	0	0	0	108.6	E291 C324 K325	E291-V334 HydrophobicContact CG-CG2 4.48Å; C324-V334 CarbonylContact C-O 3.5Å; C324-V334 VanDerWaalsContact CA-O 3.26Å; C324-V334 WeakPolarHBondContact CA-O 3.41Å; K325-V334 PolarHBondContact N-O 3.48Å; K325-V334 PolarHBondContact O-N 2.82Å
335	V	69.5	Low	65.8	Low	10 Å²	10	78.4 Å²	78.4	6%	0.061	40%	0.395	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.3	119.2	179.3	-176.4	0	0	0	0	108.7	A286 K290 I292 V322 C324	A286-V335 HydrophobicContact CB-CG1 4.17Å; A286-V335 HydrophobicContact CB-CG2 3.84Å; K290-V335 PolarHBondContact O-N 3.35Å; I292-V335 HydrophobicContact CD1-CG2 4.16Å; I292-V335 HydrophobicContact CG1-CG2 4.49Å; V322-V335 HydrophobicContact CG1-CG1 4.07Å; C324-V335 HydrophobicContact CB-CG2 4.43Å
336	S	62.2	Low	65.5	Low	57 Å²	57	78.6 Å²	78.6	40%	0.399	40%	0.398	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.6	-51.1	174.3	-59.4	0	0	0	0	110.6	Y323	Y323-S336 WeakPolarHBondContact O-CA 3.44Å; Y323-S336 WeakPolarHBondContact O-CB 3.15Å; Y323-S336 PolarHBondContact O-N 2.9Å
337	H	59.9	Low	65.2	Low	143 Å²	143	77.1 Å²	77.1	66%	0.662	39%	0.39	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-146.4	133.1	176.1	-67.1	-54.7	0	0	0	110.5	V322 Y323	V322-H337 WeakPolarHBondContact CA-O 3.43Å; Y323-H337 PolarHBondContact N-O 3.48Å; Y323-H337 PolarHBondContact O-N 3.43Å
338	S	59.5	Low	65.1	Low	29 Å²	29	82.6 Å²	82.6	20%	0.203	41%	0.407	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.9	141.1	173.8	49.9	0	0	0	0	109.5	A286	A286-S338 PolarHBondContact O-OG 3.23Å; A286-S338 VanDerWaalsContact O-OG 3.08Å
339	T	59.2	Low	65.3	Low	64 Å²	64	82.1 Å²	82.1	39%	0.393	41%	0.405	S	S	.	.			trans	-78.2	132.3	171.3	-53.5	0	0	0	0	108.7	L219 M321	L219-T339 HydrophobicContact CD2-CG2 4.36Å; M321-T339 PolarHBondContact O-N 2.91Å; M321-T339 PolarHBondContact O-OG1 3.1Å; M321-T339 VanDerWaalsContact O-OG1 3.07Å
340	H	56.8	Low	65.5	Low	61 Å²	61	81.4 Å²	81.4	28%	0.282	39%	0.392	S	S	.	.			trans	-70.4	138.9	-179.9	-66.8	-80.1	0	0	0	111.4	V287 F343 Q347	V287-H340 WeakPolarHBondContact CG1-ND1 3.19Å; H340-F343 HydrophobicContact CB-CD2 4.47Å; H340-Q347 PolarHBondContact ND1-NE2 3.03Å
341	R	57.5	Low	65.8	Low	31 Å²	31	79.8 Å²	79.8	12%	0.117	39%	0.387	C	S	.	.	S	Bend	trans	-73.7	-29.7	176.1	-174.7	171.1	176.1	-178.2	-14	112.8	I243 F244 V245 A247 L280	I243-R341 PolarHBondContact O-NH2 3.47Å; F244-R341 VanDerWaalsContact O-CZ 3.23Å; F244-R341 PolarHBondContact O-NE 2.88Å; F244-R341 VanDerWaalsContact O-NE 3.1Å; F244-R341 PolarHBondContact O-NH2 3.46Å; V245-R341 PolarHBondContact O-NE 3.34Å; V245-R341 VanDerWaalsContact O-NE 3.16Å; A247-R341 PolarHBondContact O-NH2 3.29Å; L280-R341 VanDerWaalsContact C-NH1 3.27Å; L280-R341 HydrophobicContact CD2-CG 4.41Å; L280-R341 PolarHBondContact O-NH1 3.47Å
342	T	52.9	Low	66.3	Low	58 Å²	58	81.7 Å²	81.7	36%	0.356	40%	0.395	S	S	.	.	S	Bend	trans	-137.2	128.5	174	47.6	0	0	0	0	108.5	V245 G344 Q347	V245-T342 HydrophobicContact CG1-CG2 3.36Å; T342-G344 PolarHBondContact O-N 3.13Å; T342-Q347 VanDerWaalsContact O-CD 3.3Å; T342-Q347 PolarHBondContact O-NE2 2.84Å; T342-Q347 PolarHBondContact O-OE1 2.92Å
343	F	55.2	Low	66.8	Low	85 Å²	85	82.8 Å²	82.8	37%	0.373	40%	0.404	S	S	.	.			trans	-95.7	83.2	-179.8	-153.2	-102.7	0	0	0	110.4	D221 H340 Q347 W348 L351	D221-F343 PolarHBondContact OD2-N 3.28Å; H340-F343 HydrophobicContact CB-CD2 4.47Å; F343-Q347 VanDerWaalsContact CD2-OE1 3.28Å; F343-Q347 HydrophobicContact CE2-CB 4.47Å; F343-W348 AromaticContact CD1-CD1 3.74Å; F343-W348 AromaticContact CD1-NE1 3.4Å; F343-W348 AromaticContact CE1-CD1 3.6Å; F343-W348 AromaticContact CE1-CD2 3.86Å; F343-W348 HydrophobicContact CE1-CD2 3.86Å; F343-W348 AromaticContact CE1-CE2 3.43Å; F343-W348 VanDerWaalsContact CE1-CE2 3.43Å; F343-W348 AromaticContact CE1-CG 3.99Å; F343-W348 HydrophobicContact CE1-CG 3.99Å; F343-W348 AromaticContact CE1-CZ2 3.89Å; F343-W348 HydrophobicContact CE1-CZ2 3.89Å; F343-W348 AromaticContact CE1-NE1 3.28Å; F343-W348 VanDerWaalsContact CE1-NE1 3.28Å; F343-L351 HydrophobicContact CE2-CD1 4.17Å; F343-L351 HydrophobicContact CZ-CD1 3.55Å
344	G	63.8	Low	67.5	Low	30 Å²	30	86 Å²	86	31%	0.309	42%	0.423	S	S	.	.			trans	-82.4	166	-174.8	0	0	0	0	0	114.3	T342 Q346 Q347 W348	T342-G344 PolarHBondContact O-N 3.13Å; G344-Q346 PolarHBondContact O-N 3.36Å; G344-Q347 PolarHBondContact O-N 3.29Å; G344-Q347 VanDerWaalsContact O-N 3.08Å; G344-W348 PolarHBondContact O-N 3.5Å
345	K	59.5	Low	68.4	Low	183 Å²	183	88.5 Å²	88.5	80%	0.796	43%	0.434	S	S	*	.	H	α-helix	trans	-57.8	-32.1	173.2	-167.1	177.1	-178.7	-178	0	113	W348 Q349	K345-W348 WeakPolarHBondContact O-CB 3.28Å; K345-W348 PolarHBondContact O-N 3.13Å; K345-Q349 PolarHBondContact O-N 2.84Å
346	Q	65.3	Low	69.2	Low	155 Å²	155	90 Å²	90	72%	0.724	45%	0.446	S	S	*	.	H	α-helix	trans	-66.7	-35.7	176.9	-67.6	-173.1	-5.2	0	0	112.5	G344 Q349 Q350	G344-Q346 PolarHBondContact O-N 3.36Å; Q346-Q349 PolarHBondContact O-N 3.5Å; Q346-Q350 WeakPolarHBondContact O-CG 3.46Å; Q346-Q350 PolarHBondContact O-N 3.31Å
347	Q	67.2	Low	70.6	Confident	32 Å²	32	89.7 Å²	89.7	15%	0.15	44%	0.443	C	S	.	.	H	α-helix	trans	-73.1	-37.7	176.5	-68.1	165.7	12.3	0	0	111.1	H340 T342 F343 G344 Q349 Q350 L351	H340-Q347 PolarHBondContact ND1-NE2 3.03Å; T342-Q347 VanDerWaalsContact O-CD 3.3Å; T342-Q347 PolarHBondContact O-NE2 2.84Å; T342-Q347 PolarHBondContact O-OE1 2.92Å; F343-Q347 VanDerWaalsContact CD2-OE1 3.28Å; F343-Q347 HydrophobicContact CE2-CB 4.47Å; G344-Q347 PolarHBondContact O-N 3.29Å; G344-Q347 VanDerWaalsContact O-N 3.08Å; Q347-Q349 PolarHBondContact O-N 2.82Å; Q347-Q350 PolarHBondContact O-N 3.35Å; Q347-L351 WeakPolarHBondContact O-CB 3.38Å; Q347-L351 PolarHBondContact O-N 3.47Å
348	W	73.8	Confident	72	Confident	164 Å²	164	91 Å²	91	62%	0.621	44%	0.443	S	S	*	.	H	α-helix	trans	-56.3	-41.4	169	-90.3	108.8	0	0	0	112.2	F343 G344 K345 L351 Y352	F343-W348 AromaticContact CD1-CD1 3.74Å; F343-W348 AromaticContact CD1-NE1 3.4Å; F343-W348 AromaticContact CE1-CD1 3.6Å; F343-W348 AromaticContact CE1-CD2 3.86Å; F343-W348 HydrophobicContact CE1-CD2 3.86Å; F343-W348 AromaticContact CE1-CE2 3.43Å; F343-W348 VanDerWaalsContact CE1-CE2 3.43Å; F343-W348 AromaticContact CE1-CG 3.99Å; F343-W348 HydrophobicContact CE1-CG 3.99Å; F343-W348 AromaticContact CE1-CZ2 3.89Å; F343-W348 HydrophobicContact CE1-CZ2 3.89Å; F343-W348 AromaticContact CE1-NE1 3.28Å; F343-W348 VanDerWaalsContact CE1-NE1 3.28Å; G344-W348 PolarHBondContact O-N 3.5Å; K345-W348 WeakPolarHBondContact O-CB 3.28Å; K345-W348 PolarHBondContact O-N 3.13Å; W348-L351 PolarHBondContact O-N 2.82Å; W348-Y352 VanDerWaalsContact O-CB 3.29Å; W348-Y352 WeakPolarHBondContact O-CB 3.45Å; W348-Y352 PolarHBondContact O-N 2.82Å
349	Q	75	Confident	73.6	Confident	118 Å²	118	97.1 Å²	97.1	55%	0.551	47%	0.465	S	S	*	.	H	α-helix	trans	-67.8	-44.8	177.8	-166.9	171.3	-11.3	0	0	111.5	K345 Q346 Q347 L351 Y352 D353	K345-Q349 PolarHBondContact O-N 2.84Å; Q346-Q349 PolarHBondContact O-N 3.5Å; Q347-Q349 PolarHBondContact O-N 2.82Å; Q349-L351 VanDerWaalsContact C-N 3.33Å; Q349-L351 PolarHBondContact O-N 3.4Å; Q349-Y352 WeakPolarHBondContact O-CB 3.49Å; Q349-Y352 PolarHBondContact O-N 3.41Å; Q349-D353 WeakPolarHBondContact O-CB 3.41Å; Q349-D353 PolarHBondContact O-N 3.41Å
350	Q	77	Confident	75.1	Confident	123 Å²	123	96.5 Å²	96.5	58%	0.575	47%	0.467	S	S	*	.	H	α-helix	trans	-60.6	-40.1	174.4	-72.5	175.8	-11.2	0	0	112.8	Q346 Q347 D353 T354	Q346-Q350 WeakPolarHBondContact O-CG 3.46Å; Q346-Q350 PolarHBondContact O-N 3.31Å; Q347-Q350 PolarHBondContact O-N 3.35Å; Q350-D353 PolarHBondContact O-N 2.89Å; Q350-T354 WeakPolarHBondContact O-CB 3.46Å; Q350-T354 PolarHBondContact O-N 2.92Å; Q350-T354 PolarHBondContact O-OG1 2.85Å
351	L	79	Confident	76.7	Confident	86 Å²	86	98.4 Å²	98.4	45%	0.45	48%	0.479	S	S	.	.	H	α-helix	trans	-64.6	-44.8	173.9	-98.6	159.3	0	0	0	111.6	F343 Q347 W348 Q349 D353 T354 L355	F343-L351 HydrophobicContact CE2-CD1 4.17Å; F343-L351 HydrophobicContact CZ-CD1 3.55Å; Q347-L351 WeakPolarHBondContact O-CB 3.38Å; Q347-L351 PolarHBondContact O-N 3.47Å; W348-L351 PolarHBondContact O-N 2.82Å; Q349-L351 VanDerWaalsContact C-N 3.33Å; Q349-L351 PolarHBondContact O-N 3.4Å; L351-D353 VanDerWaalsContact C-N 3.33Å; L351-D353 PolarHBondContact O-N 2.97Å; L351-T354 PolarHBondContact O-N 3.33Å; L351-L355 VanDerWaalsContact O-CB 3.23Å; L351-L355 WeakPolarHBondContact O-CB 3.45Å; L351-L355 PolarHBondContact O-N 2.73Å
352	Y	81.1	Confident	78.2	Confident	164 Å²	164	102.8 Å²	102.8	64%	0.643	50%	0.504	S	S	*	.	H	α-helix	trans	-60.7	-43.2	177.2	-177.9	-93.9	0	0	0	111.6	W348 Q349 L355 S356	W348-Y352 VanDerWaalsContact O-CB 3.29Å; W348-Y352 WeakPolarHBondContact O-CB 3.45Å; W348-Y352 PolarHBondContact O-N 2.82Å; Q349-Y352 WeakPolarHBondContact O-CB 3.49Å; Q349-Y352 PolarHBondContact O-N 3.41Å; Y352-L355 PolarHBondContact O-N 3.45Å; Y352-S356 WeakPolarHBondContact O-CB 3.41Å; Y352-S356 PolarHBondContact O-N 3.09Å; Y352-S356 PolarHBondContact O-OG 3.41Å
353	D	86.4	Confident	80	Confident	88 Å²	88	102.3 Å²	102.3	47%	0.471	51%	0.507	S	S	.	.	H	α-helix	trans	-66.3	-42.7	178.3	-67.4	-23.3	0	0	0	111.1	Q349 Q350 L351 S356 S357	Q349-D353 WeakPolarHBondContact O-CB 3.41Å; Q349-D353 PolarHBondContact O-N 3.41Å; Q350-D353 PolarHBondContact O-N 2.89Å; L351-D353 VanDerWaalsContact C-N 3.33Å; L351-D353 PolarHBondContact O-N 2.97Å; D353-S356 PolarHBondContact O-N 3.42Å; D353-S357 WeakPolarHBondContact O-CB 3.22Å; D353-S357 PolarHBondContact O-N 3.46Å
354	T	85.5	Confident	81.6	Confident	67 Å²	67	102.4 Å²	102.4	41%	0.411	51%	0.514	S	S	.	.	H	α-helix	trans	-63.6	-46	176.6	-51.8	0	0	0	0	111.1	Q350 L351 S356 S357 W358	Q350-T354 WeakPolarHBondContact O-CB 3.46Å; Q350-T354 PolarHBondContact O-N 2.92Å; Q350-T354 PolarHBondContact O-OG1 2.85Å; L351-T354 PolarHBondContact O-N 3.33Å; T354-S356 VanDerWaalsContact C-N 3.34Å; T354-S356 PolarHBondContact O-N 3.05Å; T354-S357 WeakPolarHBondContact O-CB 3.42Å; T354-S357 PolarHBondContact O-N 3.41Å; T354-S357 PolarHBondContact O-OG 3.09Å; T354-W358 HydrophobicContact CG2-CZ2 4.42Å; T354-W358 PolarHBondContact O-N 2.89Å
355	L	89.2	Confident	82.9	Confident	110 Å²	110	105.1 Å²	105.1	58%	0.576	53%	0.525	S	S	*	.	H	α-helix	trans	-67.8	-36.4	179.6	-160.8	147	0	0	0	111.4	L351 Y352 W358 K359	L351-L355 VanDerWaalsContact O-CB 3.23Å; L351-L355 WeakPolarHBondContact O-CB 3.45Å; L351-L355 PolarHBondContact O-N 2.73Å; Y352-L355 PolarHBondContact O-N 3.45Å; L355-W358 PolarHBondContact O-N 2.98Å; L355-K359 WeakPolarHBondContact O-CB 3.49Å; L355-K359 PolarHBondContact O-N 3.37Å
356	S	88	Confident	84.4	Confident	43 Å²	43	102.8 Å²	102.8	30%	0.301	52%	0.515	S	S	.	.	H	α-helix	trans	-63.8	-41.4	171.8	-64.1	0	0	0	0	111.4	Y352 D353 T354 K359 A360	Y352-S356 WeakPolarHBondContact O-CB 3.41Å; Y352-S356 PolarHBondContact O-N 3.09Å; Y352-S356 PolarHBondContact O-OG 3.41Å; D353-S356 PolarHBondContact O-N 3.42Å; T354-S356 VanDerWaalsContact C-N 3.34Å; T354-S356 PolarHBondContact O-N 3.05Å; S356-K359 PolarHBondContact O-N 2.92Å; S356-A360 WeakPolarHBondContact O-CB 3.48Å; S356-A360 PolarHBondContact O-N 3.49Å
357	S	90.1	Very high	85.5	Confident	50 Å²	50	99.1 Å²	99.1	35%	0.35	50%	0.503	S	S	.	.	H	α-helix	trans	-64	-40.9	175.1	82	0	0	0	0	112.1	D353 T354 A360 N361	D353-S357 WeakPolarHBondContact O-CB 3.22Å; D353-S357 PolarHBondContact O-N 3.46Å; T354-S357 WeakPolarHBondContact O-CB 3.42Å; T354-S357 PolarHBondContact O-N 3.41Å; T354-S357 PolarHBondContact O-OG 3.09Å; S357-A360 PolarHBondContact O-N 3.29Å; S357-N361 WeakPolarHBondContact O-CB 3.48Å; S357-N361 PolarHBondContact O-N 3.37Å; S357-N361 PolarHBondContact O-ND2 2.95Å
358	W	90	Very high	86.3	Confident	171 Å²	171	100.2 Å²	100.2	65%	0.648	51%	0.514	S	S	*	.	H	α-helix	trans	-66.8	-42.2	176.6	-72.8	8.7	0	0	0	111.7	T354 L355 A360 N361 L362	T354-W358 HydrophobicContact CG2-CZ2 4.42Å; T354-W358 PolarHBondContact O-N 2.89Å; L355-W358 PolarHBondContact O-N 2.98Å; W358-A360 VanDerWaalsContact C-N 3.31Å; W358-A360 PolarHBondContact O-N 3.5Å; W358-N361 PolarHBondContact O-N 2.91Å; W358-L362 WeakPolarHBondContact O-CB 3.46Å; W358-L362 PolarHBondContact O-N 3.46Å
359	K	92.2	Very high	86.8	Confident	156 Å²	156	97.8 Å²	97.8	68%	0.678	51%	0.513	S	S	*	.	H	α-helix	trans	-60	-43.3	173.9	-175.9	179.4	177.9	-179.1	0	111.1	L355 S356 A363	L355-K359 WeakPolarHBondContact O-CB 3.49Å; L355-K359 PolarHBondContact O-N 3.37Å; S356-K359 PolarHBondContact O-N 2.92Å; K359-A363 VanDerWaalsContact O-CB 3.25Å; K359-A363 WeakPolarHBondContact O-CB 3.47Å; K359-A363 PolarHBondContact O-N 3.31Å
360	A	91.1	Very high	87.1	Confident	52 Å²	52	97.7 Å²	97.7	43%	0.43	51%	0.512	S	S	.	.	H	α-helix	trans	-63.2	-47.2	175.7	0	0	0	0	0	111.4	S356 S357 W358 L362 A363 T364	S356-A360 WeakPolarHBondContact O-CB 3.48Å; S356-A360 PolarHBondContact O-N 3.49Å; S357-A360 PolarHBondContact O-N 3.29Å; W358-A360 VanDerWaalsContact C-N 3.31Å; W358-A360 PolarHBondContact O-N 3.5Å; A360-L362 PolarHBondContact O-N 2.97Å; A360-A363 PolarHBondContact O-N 3.38Å; A360-T364 PolarHBondContact O-N 3.28Å; A360-T364 PolarHBondContact O-OG1 3.43Å
361	N	90.6	Very high	87.2	Confident	100 Å²	100	96.7 Å²	96.7	54%	0.535	52%	0.515	S	S	.	.	H	α-helix	trans	-62	-43.9	178.6	-69.9	-23.1	0	0	0	112.3	S357 W358 T364 V365	S357-N361 WeakPolarHBondContact O-CB 3.48Å; S357-N361 PolarHBondContact O-N 3.37Å; S357-N361 PolarHBondContact O-ND2 2.95Å; W358-N361 PolarHBondContact O-N 2.91Å; N361-T364 PolarHBondContact O-N 3.36Å; N361-V365 VanDerWaalsContact O-CG2 3.29Å; N361-V365 WeakPolarHBondContact O-CG2 3.41Å; N361-V365 PolarHBondContact O-N 3.03Å
362	L	90.1	Very high	86.9	Confident	123 Å²	123	99.6 Å²	99.6	64%	0.644	53%	0.53	S	S	*	.	H	α-helix	trans	-64.7	-39	174.9	-89	152.2	0	0	0	112.2	W358 A360 V365 K366	W358-L362 WeakPolarHBondContact O-CB 3.46Å; W358-L362 PolarHBondContact O-N 3.46Å; A360-L362 PolarHBondContact O-N 2.97Å; L362-V365 PolarHBondContact O-N 2.84Å; L362-K366 VanDerWaalsContact O-CB 3.26Å; L362-K366 WeakPolarHBondContact O-CB 3.48Å; L362-K366 PolarHBondContact O-N 3.22Å
363	A	89.3	Confident	85.9	Confident	49 Å²	49	95.3 Å²	95.3	41%	0.405	52%	0.524	S	S	.	.	H	α-helix	trans	-65	-43.6	175.5	0	0	0	0	0	111.1	K359 A360 K366 T367	K359-A363 VanDerWaalsContact O-CB 3.25Å; K359-A363 WeakPolarHBondContact O-CB 3.47Å; K359-A363 PolarHBondContact O-N 3.31Å; A360-A363 PolarHBondContact O-N 3.38Å; A363-K366 PolarHBondContact O-N 3.31Å; A363-T367 WeakPolarHBondContact O-CB 3.25Å; A363-T367 PolarHBondContact O-N 3.28Å; A363-T367 PolarHBondContact O-OG1 2.71Å
364	T	89.8	Confident	84.5	Confident	86 Å²	86	95.8 Å²	95.8	53%	0.528	53%	0.532	S	S	.	.	H	α-helix	trans	-60.7	-49.8	174.8	-56.8	0	0	0	0	111	A360 N361 K366 T367 S368	A360-T364 PolarHBondContact O-N 3.28Å; A360-T364 PolarHBondContact O-OG1 3.43Å; N361-T364 PolarHBondContact O-N 3.36Å; T364-K366 VanDerWaalsContact C-N 3.34Å; T364-K366 PolarHBondContact O-N 3.39Å; T364-T367 PolarHBondContact O-N 3.19Å; T364-T367 VanDerWaalsContact O-N 3.15Å; T364-S368 WeakPolarHBondContact O-CB 3.31Å; T364-S368 PolarHBondContact O-N 2.74Å; T364-S368 PolarHBondContact O-OG 2.79Å; T364-S368 VanDerWaalsContact O-OG 3.09Å
365	V	91.3	Very high	82.8	Confident	88 Å²	88	98.2 Å²	98.2	53%	0.533	55%	0.552	S	S	.	*	H	α-helix	trans	-59.4	-44.2	177	170.8	0	0	0	0	111.2	N361 L362 T367 S368 L369	N361-V365 VanDerWaalsContact O-CG2 3.29Å; N361-V365 WeakPolarHBondContact O-CG2 3.41Å; N361-V365 PolarHBondContact O-N 3.03Å; L362-V365 PolarHBondContact O-N 2.84Å; V365-T367 VanDerWaalsContact C-N 3.31Å; V365-T367 PolarHBondContact O-N 2.8Å; V365-S368 PolarHBondContact O-N 3.38Å; V365-L369 WeakPolarHBondContact O-CB 3.28Å; V365-L369 PolarHBondContact O-N 3.18Å
366	K	90.4	Very high	80.4	Confident	134 Å²	134	101.2 Å²	101.2	58%	0.583	59%	0.592	S	S	*	*	H	α-helix	trans	-60.8	-42.1	176.5	-176.9	178.7	179.2	-179.8	0	111.6	L362 A363 T364 L369 Q370	L362-K366 VanDerWaalsContact O-CB 3.26Å; L362-K366 WeakPolarHBondContact O-CB 3.48Å; L362-K366 PolarHBondContact O-N 3.22Å; A363-K366 PolarHBondContact O-N 3.31Å; T364-K366 VanDerWaalsContact C-N 3.34Å; T364-K366 PolarHBondContact O-N 3.39Å; K366-L369 PolarHBondContact O-N 3.22Å; K366-Q370 WeakPolarHBondContact O-CB 3.17Å; K366-Q370 VanDerWaalsContact O-CG 3.3Å; K366-Q370 WeakPolarHBondContact O-CG 3.46Å; K366-Q370 PolarHBondContact O-N 2.9Å
367	T	87.8	Confident	80	Confident	78 Å²	78	104.1 Å²	104.1	48%	0.479	61%	0.606	S	S	.	*	H	α-helix	trans	-67.4	-44.8	179.3	-51.9	0	0	0	0	110.2	A363 T364 V365 L369 Q370 T371	A363-T367 WeakPolarHBondContact O-CB 3.25Å; A363-T367 PolarHBondContact O-N 3.28Å; A363-T367 PolarHBondContact O-OG1 2.71Å; T364-T367 PolarHBondContact O-N 3.19Å; T364-T367 VanDerWaalsContact O-N 3.15Å; V365-T367 VanDerWaalsContact C-N 3.31Å; V365-T367 PolarHBondContact O-N 2.8Å; T367-L369 VanDerWaalsContact C-N 3.3Å; T367-L369 PolarHBondContact O-N 3.08Å; T367-Q370 PolarHBondContact O-N 2.98Å; T367-T371 WeakPolarHBondContact O-CG2 3.09Å; T367-T371 PolarHBondContact O-N 3.09Å; T367-T371 PolarHBondContact O-OG1 3.42Å; T367-T371 VanDerWaalsContact O-OG1 3.11Å
368	S	85.4	Confident	79.5	Confident	55 Å²	55	106.9 Å²	106.9	39%	0.385	62%	0.62	S	S	.	*	H	α-helix	trans	-58.9	-41.2	173.7	-62.9	0	0	0	0	111.9	T364 V365 T371 L372	T364-S368 WeakPolarHBondContact O-CB 3.31Å; T364-S368 PolarHBondContact O-N 2.74Å; T364-S368 PolarHBondContact O-OG 2.79Å; T364-S368 VanDerWaalsContact O-OG 3.09Å; V365-S368 PolarHBondContact O-N 3.38Å; S368-T371 VanDerWaalsContact C-OG1 3.32Å; S368-T371 VanDerWaalsContact CA-OG1 3.27Å; S368-T371 WeakPolarHBondContact CA-OG1 3.3Å; S368-T371 PolarHBondContact O-N 3.49Å; S368-T371 PolarHBondContact O-OG1 3.43Å; S368-L372 WeakPolarHBondContact O-CB 3.35Å; S368-L372 WeakPolarHBondContact O-CD1 3.32Å; S368-L372 WeakPolarHBondContact O-CG 3.34Å; S368-L372 PolarHBondContact O-N 3.04Å
369	L	83.9	Confident	78.9	Confident	113 Å²	113	103.4 Å²	103.4	59%	0.592	62%	0.618	S	S	*	*	H	α-helix	trans	-65.4	-44.6	176	-133.2	113.6	0	0	0	111.3	V365 K366 T367 T371 L372 S373	V365-L369 WeakPolarHBondContact O-CB 3.28Å; V365-L369 PolarHBondContact O-N 3.18Å; K366-L369 PolarHBondContact O-N 3.22Å; T367-L369 VanDerWaalsContact C-N 3.3Å; T367-L369 PolarHBondContact O-N 3.08Å; L369-T371 VanDerWaalsContact C-N 3.32Å; L369-T371 PolarHBondContact O-N 3.24Å; L369-L372 PolarHBondContact O-N 3.48Å; L369-L372 VanDerWaalsContact O-N 3.11Å; L369-S373 PolarHBondContact O-N 2.88Å; L369-S373 PolarHBondContact O-OG 3.02Å
370	Q	80.9	Confident	78.1	Confident	115 Å²	115	100.3 Å²	100.3	54%	0.537	62%	0.615	S	S	.	*	H	α-helix	trans	-64.3	-33.9	176.8	-74.8	178.3	-31.6	0	0	112.9	K366 T367 L372 S373	K366-Q370 WeakPolarHBondContact O-CB 3.17Å; K366-Q370 VanDerWaalsContact O-CG 3.3Å; K366-Q370 WeakPolarHBondContact O-CG 3.46Å; K366-Q370 PolarHBondContact O-N 2.9Å; T367-Q370 PolarHBondContact O-N 2.98Å; Q370-L372 VanDerWaalsContact C-N 3.35Å; Q370-S373 CarbonylContact O-C 3.38Å
371	T	78.9	Confident	77.3	Confident	103 Å²	103	103.3 Å²	103.3	63%	0.632	63%	0.626	S	S	*	*	H	α-helix	trans	-73.7	-26.1	173.3	52	0	0	0	0	113.1	T367 S368 L369	T367-T371 WeakPolarHBondContact O-CG2 3.09Å; T367-T371 PolarHBondContact O-N 3.09Å; T367-T371 PolarHBondContact O-OG1 3.42Å; T367-T371 VanDerWaalsContact O-OG1 3.11Å; S368-T371 VanDerWaalsContact C-OG1 3.32Å; S368-T371 VanDerWaalsContact CA-OG1 3.27Å; S368-T371 WeakPolarHBondContact CA-OG1 3.3Å; S368-T371 PolarHBondContact O-N 3.49Å; S368-T371 PolarHBondContact O-OG1 3.43Å; L369-T371 VanDerWaalsContact C-N 3.32Å; L369-T371 PolarHBondContact O-N 3.24Å
372	L	72.3	Confident	76.4	Confident	146 Å²	146	103.5 Å²	103.5	76%	0.764	63%	0.633	S	S	*	*	H	α-helix	trans	-84	-26.6	177.1	-83.7	158.4	0	0	0	112.8	S368 L369 Q370 P374	S368-L372 WeakPolarHBondContact O-CB 3.35Å; S368-L372 WeakPolarHBondContact O-CD1 3.32Å; S368-L372 WeakPolarHBondContact O-CG 3.34Å; S368-L372 PolarHBondContact O-N 3.04Å; L369-L372 PolarHBondContact O-N 3.48Å; L369-L372 VanDerWaalsContact O-N 3.11Å; Q370-L372 VanDerWaalsContact C-N 3.35Å; L372-P374 WeakPolarHBondContact O-CD 3.3Å
373	S	60	Low	75.5	Confident	75 Å²	75	102.1 Å²	102.1	52%	0.524	63%	0.632	S	S	.	*			trans	-109.9	69.4	169.9	60.7	0	0	0	0	110.3	L369 Q370 S375	L369-S373 PolarHBondContact O-N 2.88Å; L369-S373 PolarHBondContact O-OG 3.02Å; Q370-S373 CarbonylContact O-C 3.38Å; S373-S375 PolarHBondContact O-N 3.49Å
374	P	57.3	Low	74.4	Confident	98 Å²	98	106.2 Å²	106.2	64%	0.636	65%	0.649	S	S	*	*			trans	-63.2	126.2	158.5	30.4	-27.8	0	0	0	105.7	L372 A376	L372-P374 WeakPolarHBondContact O-CD 3.3Å; P374-A376 PolarHBondContact O-N 3.25Å; P374-A376 VanDerWaalsContact O-N 3.09Å
375	S	50.3	Low	73.1	Confident	118 Å²	118	107.9 Å²	107.9	83%	0.825	66%	0.659	S	S	*	*			trans	-34.7	116.1	171.2	48.9	0	0	0	0	111.6	S373	S373-S375 PolarHBondContact O-N 3.49Å
376	A	38.7	Very low	71.4	Confident	172 Å²	172	109.7 Å²	109.7	100%	1.421	67%	0.671	S	S	*	*			trans	-68.2	0	151.9	0	0	0	0	0	109.2	P374	P374-A376 PolarHBondContact O-N 3.25Å; P374-A376 VanDerWaalsContact O-N 3.09Å

Retrieved 376 of 376 residues in 63.8 ms (Link to these results)

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