A0A087YGV4_POEFO Loading...

DNA helicase

AlphaFold DB , UniProt , Accession A0A087YGV4, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 610 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M37.7Very low36.1Very low231 Ų231129.1 Ų129.1100%1.13866%0.658SS**  033.70-75.3-144.3-80.800112.7
2A29.8Very low35.8Very low97 Ų97128.8 Ų128.880%0.80266%0.659SS**  trans-103.5-4.6-170.600000115.4
3E32.1Very low35.8Very low158 Ų158123.2 Ų123.274%0.73863%0.628SS**SBendtrans-103.4-4.5-172-69.7-177.415800115.3
4W37.6Very low35.8Very low176 Ų176122.2 Ų122.267%0.66762%0.62SS**G310 helixtrans-88.2-12.7-170.7-65.187.7000115.1A6W4-A6 VanDerWaalsContact C-N 3.32Å
5N36.8Very low35.2Very low129 Ų129125.6 Ų125.669%0.6963%0.633SS**G310 helixtrans-82-7.7177.3-73.6-23.5000113.3
6A37.7Very low34.9Very low83 Ų83125.9 Ų125.969%0.68663%0.631SS**G310 helixtrans-79.3-19.4-177.200000113.7W4W4-A6 VanDerWaalsContact C-N 3.32Å
7F36.4Very low35Very low134 Ų134122 Ų12259%0.58861%0.61SS**SBendtrans-105.3-7.4-166.5-67.1-79.2000115.3P311F7-P311 WeakPolarHBondContact O-CG 3.33Å
8Y36Very low34.9Very low68 Ų68121.6 Ų121.627%0.26761%0.606SS.*  trans-12489.1-179.2-71.8-87.8000110.3L308 L309Y8-L308 WeakPolarHBondContact OH-CG 3.41Å; Y8-L309 PolarHBondContact OH-O 3.47Å
9Q38.1Very low34.7Very low155 Ų155120.9 Ų120.972%0.72460%0.601SS**  trans-89.9137.5155.4-79.9179.4-54.300107.8
10N35.7Very low34.7Very low79 Ų79116 Ų11642%0.42258%0.58SS.*  trans-69.1134.6-173.7-76.9-37.1000109.9D12 E13N10-D12 VanDerWaalsContact C-N 3.28Å; N10-D12 PolarHBondContact O-N 3.12Å; N10-E13 HydrophobicContact CB-CG 4.27Å; N10-E13 PolarHBondContact N-OE1 3.41Å; N10-E13 WeakPolarHBondContact O-CB 3.33Å; N10-E13 WeakPolarHBondContact O-CG 3.39Å; N10-E13 PolarHBondContact O-N 3.34Å
11E39.6Very low35Very low110 Ų110113.6 Ų113.651%0.51457%0.567SS.*THydrogen-bonded Turntrans-77.4-11.7-180-61.3-165.5139.800113.7E13 K316E11-E13 PolarHBondContact O-N 2.97Å; E11-K316 WeakPolarHBondContact OE1-CE 3.44Å; E11-K316 IonicContact OE1-NZ 3Å; E11-K316 PolarHBondContact OE1-NZ 3.17Å; E11-K316 IonicContact OE2-NZ 2.64Å; E11-K316 PolarHBondContact OE2-NZ 3.48Å
12D32.3Very low35.1Very low125 Ų125106 Ų10667%0.66853%0.531SS*.THydrogen-bonded Turntrans-67-11.6167.5-67.1-33.1000112N10 E14 E16N10-D12 VanDerWaalsContact C-N 3.28Å; N10-D12 PolarHBondContact O-N 3.12Å; D12-E14 VanDerWaalsContact C-N 3.3Å; D12-E14 PolarHBondContact O-N 3.31Å; D12-E16 PolarHBondContact O-N 3.43Å
13E36.3Very low35.4Very low57 Ų57103.7 Ų103.727%0.26651%0.509SS..Hα-helixtrans-66.9-21.3177.5-69.7175.5-159.900113.1N10 E11 E16 Q17N10-E13 HydrophobicContact CB-CG 4.27Å; N10-E13 PolarHBondContact N-OE1 3.41Å; N10-E13 WeakPolarHBondContact O-CB 3.33Å; N10-E13 WeakPolarHBondContact O-CG 3.39Å; N10-E13 PolarHBondContact O-N 3.34Å; E11-E13 PolarHBondContact O-N 2.97Å; E13-E16 CarbonylContact O-C 3.6Å; E13-Q17 HydrophobicContact CB-CG 4.36Å; E13-Q17 VanDerWaalsContact O-CA 3.3Å; E13-Q17 WeakPolarHBondContact O-CA 3.14Å; E13-Q17 WeakPolarHBondContact O-CB 3.24Å; E13-Q17 VanDerWaalsContact O-CD 3.3Å; E13-Q17 WeakPolarHBondContact O-CG 3.44Å; E13-Q17 PolarHBondContact O-N 2.61Å; E13-Q17 PolarHBondContact OE2-NE2 3.25Å
14E35Very low35.4Very low109 Ų10997.6 Ų97.651%0.50949%0.488SS..Hα-helixtrans-74-37.9-174.6-75.5-167.616600114.3D12 K336D12-E14 VanDerWaalsContact C-N 3.3Å; D12-E14 PolarHBondContact O-N 3.31Å; E14-K336 IonicContact OE1-NZ 2.73Å
15Q27.6Very low35.1Very low173 Ų17390.6 Ų90.681%0.80847%0.471SS*.Hα-helixtrans-79.1-36.3171.9-94.2-178.7-13.100111.5Q17Q15-Q17 PolarHBondContact O-N 3.4Å
16E30.1Very low34.8Very low131 Ų13192.4 Ų92.461%0.61248%0.48SS*.Hα-helixtrans-64.5-25.3169.4-72.9-176.5158.200111.6D12 E13 E19 A20D12-E16 PolarHBondContact O-N 3.43Å; E13-E16 CarbonylContact O-C 3.6Å; E16-E19 CarbonylContact O-C 3.55Å; E16-A20 WeakPolarHBondContact O-CA 3.3Å; E16-A20 WeakPolarHBondContact O-CB 3.4Å; E16-A20 PolarHBondContact O-N 3.17Å
17Q36.9Very low34.9Very low59 Ų5994 Ų9428%0.27647%0.469SS..Hα-helixtrans-79.1-34.3-177.2-88.7168.229.500114.1E13 Q15 E19 A20 E21E13-Q17 HydrophobicContact CB-CG 4.36Å; E13-Q17 VanDerWaalsContact O-CA 3.3Å; E13-Q17 WeakPolarHBondContact O-CA 3.14Å; E13-Q17 WeakPolarHBondContact O-CB 3.24Å; E13-Q17 VanDerWaalsContact O-CD 3.3Å; E13-Q17 WeakPolarHBondContact O-CG 3.44Å; E13-Q17 PolarHBondContact O-N 2.61Å; E13-Q17 PolarHBondContact OE2-NE2 3.25Å; Q15-Q17 PolarHBondContact O-N 3.4Å; Q17-E19 VanDerWaalsContact C-N 3.29Å; Q17-A20 CarbonylContact O-C 3.48Å; Q17-A20 PolarHBondContact O-N 3.42Å; Q17-E21 WeakPolarHBondContact O-CB 3.38Å; Q17-E21 VanDerWaalsContact O-CG 3.28Å; Q17-E21 WeakPolarHBondContact O-CG 3.33Å; Q17-E21 PolarHBondContact O-N 3.25Å
18E32.7Very low35Very low115 Ų11597.4 Ų97.454%0.53748%0.484SS..Hα-helixtrans-68.8-33.1170.3-82.4-169.5153.900111
19E31.3Very low35.4Very low108 Ų10899.1 Ų99.151%0.50550%0.501SS..Hα-helixtrans-76.1-29.1170.5-80.3-161.8-178.400113.3E16 Q17 L22 S23 R279E16-E19 CarbonylContact O-C 3.55Å; Q17-E19 VanDerWaalsContact C-N 3.29Å; E19-L22 WeakPolarHBondContact O-CB 3.41Å; E19-L22 PolarHBondContact O-N 2.74Å; E19-S23 PolarHBondContact O-N 2.84Å; E19-R279 PolarHBondContact O-NH2 3.44Å; E19-R279 VanDerWaalsContact O-NH2 3.14Å; E19-R279 IonicContact OE2-CZ 3.88Å; E19-R279 IonicContact OE2-NH1 3.69Å; E19-R279 PolarHBondContact OE2-NH1 2.8Å; E19-R279 IonicContact OE2-NH2 3.56Å
20A34.4Very low36.2Very low22 Ų2295.2 Ų95.218%0.18249%0.491CS..Hα-helixtrans-81.9-22176.500000112.9E16 Q17 L22 S23 G24 G25E16-A20 WeakPolarHBondContact O-CA 3.3Å; E16-A20 WeakPolarHBondContact O-CB 3.4Å; E16-A20 PolarHBondContact O-N 3.17Å; Q17-A20 CarbonylContact O-C 3.48Å; Q17-A20 PolarHBondContact O-N 3.42Å; A20-L22 PolarHBondContact O-N 3.31Å; A20-S23 VanDerWaalsContact CA-OG 3.31Å; A20-S23 WeakPolarHBondContact CA-OG 3.41Å; A20-S23 PolarHBondContact O-N 3.38Å; A20-G24 CarbonylContact O-C 3.58Å; A20-G24 VanDerWaalsContact O-C 3.23Å; A20-G24 PolarHBondContact O-N 2.97Å; A20-G24 VanDerWaalsContact O-N 3.1Å; A20-G25 PolarHBondContact O-N 2.95Å
21E40.6Very low37.8Very low66 Ų6692 Ų9231%0.30848%0.476SS..THydrogen-bonded Turntrans-57.6-30.1163.1-85.3-179.9-167.400110.7Q17 R361 R401 Y404Q17-E21 WeakPolarHBondContact O-CB 3.38Å; Q17-E21 VanDerWaalsContact O-CG 3.28Å; Q17-E21 WeakPolarHBondContact O-CG 3.33Å; Q17-E21 PolarHBondContact O-N 3.25Å; E21-R361 IonicContact OE2-NH1 2.93Å; E21-R401 IonicContact OE1-CZ 3.85Å; E21-R401 IonicContact OE1-NE 2.79Å; E21-R401 PolarHBondContact OE1-NE 3.29Å; E21-R401 VanDerWaalsContact OE1-NE 3.13Å; E21-R401 IonicContact OE1-NH2 3.91Å; E21-R401 PolarHBondContact OE1-NH2 3.12Å; E21-Y404 WeakPolarHBondContact OE1-CE2 3.19Å; E21-Y404 PolarHBondContact OE2-OH 3.29Å
22L40.5Very low40Very low72 Ų7289.6 Ų89.638%0.37746%0.462SS..THydrogen-bonded Turntrans-92.4-18175.4-69.2164.8000114.1E19 A20 V276 P362E19-L22 WeakPolarHBondContact O-CB 3.41Å; E19-L22 PolarHBondContact O-N 2.74Å; A20-L22 PolarHBondContact O-N 3.31Å; L22-V276 WeakPolarHBondContact O-CG1 3.45Å; L22-P362 HydrophobicContact CD2-CG 3.83Å
23S35Very low42.7Very low49 Ų4984.3 Ų84.334%0.34343%0.434SS..THydrogen-bonded Turntrans-98.8-1-179.878.20000114.2E19 A20E19-S23 PolarHBondContact O-N 2.84Å; A20-S23 VanDerWaalsContact CA-OG 3.31Å; A20-S23 WeakPolarHBondContact CA-OG 3.41Å; A20-S23 PolarHBondContact O-N 3.38Å
24G33.5Very low45.3Very low29 Ų2981.7 Ų81.730%0.29942%0.422SS..  trans67.3110.4-15800000107.9A20A20-G24 CarbonylContact O-C 3.58Å; A20-G24 VanDerWaalsContact O-C 3.23Å; A20-G24 PolarHBondContact O-N 2.97Å; A20-G24 VanDerWaalsContact O-N 3.1Å
25G29.5Very low48.2Very low29 Ų2976.9 Ų76.930%0.29940%0.4SS..  trans-53.9167.3177.700000111.8A20 Y27A20-G25 PolarHBondContact O-N 2.95Å; G25-Y27 WeakPolarHBondContact O-CD2 3.47Å; G25-Y27 PolarHBondContact O-N 2.92Å
26D32.4Very low51.4Low167 Ų16768.6 Ų68.689%0.89336%0.361SS*.  trans-60.971162.1-117.3-7.5000108.4K28D26-K28 PolarHBondContact O-N 2.8Å
27Y38.5Very low54.6Low117 Ų11762.4 Ų62.446%0.45933%0.332SS..  trans-57.2127.3166.7-80.8-87.2000104.5G25 V29 L254G25-Y27 WeakPolarHBondContact O-CD2 3.47Å; G25-Y27 PolarHBondContact O-N 2.92Å; Y27-V29 WeakPolarHBondContact O-CG2 3.39Å; Y27-V29 PolarHBondContact O-N 3.48Å; Y27-L254 VanDerWaalsContact CE1-O 3.31Å; Y27-L254 WeakPolarHBondContact CE1-O 3.35Å; Y27-L254 HydrophobicContact CE2-CD1 3.89Å; Y27-L254 VanDerWaalsContact CZ-O 3.27Å; Y27-L254 WeakPolarHBondContact OH-CA 3.47Å; Y27-L254 WeakPolarHBondContact OH-CD1 3.4Å; Y27-L254 VanDerWaalsContact OH-CG 3.24Å; Y27-L254 WeakPolarHBondContact OH-CG 3.44Å; Y27-L254 PolarHBondContact OH-O 2.8Å
28K38.8Very low57.5Low206 Ų20659.6 Ų59.690%0.89632%0.319SS*.  trans-55.193.6168-81.5-180177174.20107.3D26 S30D26-K28 PolarHBondContact O-N 2.8Å; K28-S30 PolarHBondContact O-N 3.29Å
29V45.3Very low60.6Low103 Ų10354.1 Ų54.162%0.62429%0.294SS*.  trans-58.8104.6179.6173.10000105.5Y27 G31Y27-V29 WeakPolarHBondContact O-CG2 3.39Å; Y27-V29 PolarHBondContact O-N 3.48Å; V29-G31 WeakPolarHBondContact CG1-O 3.44Å; V29-G31 PolarHBondContact O-N 2.8Å; V29-G31 VanDerWaalsContact O-N 3.13Å
30S53.5Low63.6Low74 Ų7449 Ų4952%0.51727%0.269SS..  trans-72.20-175.3-175.80000112.4K28 R157K28-S30 PolarHBondContact O-N 3.29Å; S30-R157 WeakPolarHBondContact O-CD 3.34Å; S30-R157 PolarHBondContact O-NE 2.85Å; S30-R157 VanDerWaalsContact O-NE 3.15Å; S30-R157 PolarHBondContact OG-NH1 2.9Å; S30-R157 PolarHBondContact OG-NH2 3.13Å
31G69.8Low66.5Low10 Ų1047.9 Ų47.910%0.10326%0.261CS..SBendtrans170.8167.5174.800000110.9V29 R157 S159V29-G31 WeakPolarHBondContact CG1-O 3.44Å; V29-G31 PolarHBondContact O-N 2.8Å; V29-G31 VanDerWaalsContact O-N 3.13Å; G31-R157 CarbonylContact C-O 3.48Å; G31-R157 WeakPolarHBondContact CA-O 3.5Å; G31-S159 PolarHBondContact O-OG 3.44Å
32R85.6Confident68.9Low60 Ų6045.1 Ų45.123%0.22625%0.249CC..EExtended strand (participates in β ladder)trans-87.2139.7172.3-66.6173175.9-148.7-8.2109.4R77 L79 E108 R157 L158 S159R32-R77 WeakPolarHBondContact CD-O 3.24Å; R32-R77 WeakPolarHBondContact CG-O 3.49Å; R32-L79 HydrophobicContact CB-CG 4.45Å; R32-E108 IonicContact CZ-OE1 3.66Å; R32-E108 IonicContact NH1-OE1 3.66Å; R32-E108 PolarHBondContact NH1-OE1 2.94Å; R32-E108 IonicContact NH2-OE1 2.76Å; R32-E108 PolarHBondContact NH2-OE1 3.43Å; R32-R157 PolarHBondContact N-O 3.26Å; R32-L158 VanDerWaalsContact O-CA 3.3Å; R32-L158 WeakPolarHBondContact O-CA 3.46Å; R32-S159 PolarHBondContact O-N 2.92Å; R32-S159 PolarHBondContact O-OG 3.11Å; R32-S159 VanDerWaalsContact O-OG 3.1Å
33D88.6Confident71.2Confident14 Ų1449.4 Ų49.48%0.07526%0.264CS..EExtended strand (participates in β ladder)trans-75.2147.1171.5-69.2-12000109.1D78 L79 S159 H160 R252D33-D78 HydrophobicContact CB-CB 4.5Å; D33-D78 CarbonylContact O-C 3.54Å; D33-D78 WeakPolarHBondContact O-CA 3.35Å; D33-L79 PolarHBondContact O-N 2.82Å; D33-S159 PolarHBondContact N-OG 3.22Å; D33-S159 WeakPolarHBondContact OD1-CB 3.41Å; D33-S159 PolarHBondContact OD1-OG 2.83Å; D33-H160 WeakPolarHBondContact OD1-CB 3.14Å; D33-H160 IonicContact OD1-CD2 3.9Å; D33-H160 PolarHBondContact OD1-CD2 2.85Å; D33-H160 IonicContact OD1-CG 3.06Å; D33-H160 IonicContact OD2-CD2 3.95Å; D33-R252 IonicContact OD2-CZ 2.76Å; D33-R252 IonicContact OD2-NE 2.69Å; D33-R252 IonicContact OD2-NH2 3.52Å; D33-R252 PolarHBondContact OD2-NH2 3.32Å
34S92.3Very high73.8Confident3 Ų351.3 Ų51.32%0.02127%0.268CS..EExtended strand (participates in β ladder)trans-129.8129.2-178.652.10000110.4L79 Y151 H160 K161 R162S34-L79 WeakPolarHBondContact CA-O 3.44Å; S34-Y151 WeakPolarHBondContact OG-CE1 2.89Å; S34-H160 PolarHBondContact N-O 3.46Å; S34-H160 PolarHBondContact OG-O 2.8Å; S34-K161 WeakPolarHBondContact OG-CA 3.23Å; S34-R162 PolarHBondContact O-N 2.84Å
35L94.4Very high76.5Confident7 Ų750 Ų504%0.03725%0.254CS..EExtended strand (participates in β ladder)trans-129.2118.9-177.6178.860.8000110F37 V67 L79 V80 A81 R162 M164 E248L35-F37 HydrophobicContact CD2-CE1 4.09Å; L35-F37 HydrophobicContact CD2-CE2 3.88Å; L35-F37 HydrophobicContact CD2-CZ 3.45Å; L35-F37 VanDerWaalsContact CD2-CZ 3.45Å; L35-F37 HydrophobicContact CG-CE1 4.47Å; L35-F37 HydrophobicContact CG-CE2 4.08Å; L35-F37 HydrophobicContact CG-CZ 4Å; L35-V67 HydrophobicContact CD2-CG1 4.06Å; L35-L79 PolarHBondContact N-O 3.49Å; L35-V80 VanDerWaalsContact O-CA 3.32Å; L35-V80 WeakPolarHBondContact O-CA 3.33Å; L35-A81 PolarHBondContact O-N 3.4Å; L35-R162 WeakPolarHBondContact CA-O 3.5Å; L35-R162 HydrophobicContact CD1-CB 4.05Å; L35-R162 HydrophobicContact CD1-CG 4.02Å; L35-M164 HydrophobicContact CD1-CE 3.92Å; L35-M164 HydrophobicContact CD1-CG 3.84Å; L35-M164 HydrophobicContact CD1-SD 3.92Å; L35-E248 HydrophobicContact CD2-CG 4.14Å
36V96.4Very high79.4Confident0 Ų050.9 Ų50.90%025%0.249CC..EExtended strand (participates in β ladder)trans-107120.6175.6179.90000108.7A81 V83 L106 C147 L150 Y151 R162 L163 M164V36-A81 HydrophobicContact CB-CB 4.44Å; V36-A81 HydrophobicContact CG1-CB 4.27Å; V36-A81 HydrophobicContact CG2-CB 4.04Å; V36-V83 HydrophobicContact CG1-CG2 4.02Å; V36-L106 HydrophobicContact CG2-CD1 4.33Å; V36-C147 HydrophobicContact CG1-CB 4.43Å; V36-L150 HydrophobicContact CG1-CD1 4.48Å; V36-Y151 HydrophobicContact CG2-CE1 3.95Å; V36-Y151 HydrophobicContact CG2-CE2 3.96Å; V36-Y151 VanDerWaalsContact CG2-CZ 3.48Å; V36-Y151 VanDerWaalsContact CG2-OH 3.31Å; V36-Y151 WeakPolarHBondContact CG2-OH 3.19Å; V36-R162 PolarHBondContact N-O 2.91Å; V36-L163 HydrophobicContact CB-CD1 3.73Å; V36-L163 HydrophobicContact CG1-CD1 3.59Å; V36-M164 PolarHBondContact O-N 3.46Å
37F97.4Very high82Confident0 Ų048 Ų480%023%0.233CC..EExtended strand (participates in β ladder)trans-86.7114.9168.7-62.6-80.1000108.8L35 V39 V64 V67 Y68 A81 L82 V83 M164 F166L35-F37 HydrophobicContact CD2-CE1 4.09Å; L35-F37 HydrophobicContact CD2-CE2 3.88Å; L35-F37 HydrophobicContact CD2-CZ 3.45Å; L35-F37 VanDerWaalsContact CD2-CZ 3.45Å; L35-F37 HydrophobicContact CG-CE1 4.47Å; L35-F37 HydrophobicContact CG-CE2 4.08Å; L35-F37 HydrophobicContact CG-CZ 4Å; F37-V39 HydrophobicContact CB-CG2 4.48Å; F37-V64 HydrophobicContact CB-CG2 4.36Å; F37-V64 HydrophobicContact CD1-CG2 3.82Å; F37-V64 HydrophobicContact CD2-CG1 4.2Å; F37-V64 HydrophobicContact CE1-CG2 4.25Å; F37-V64 HydrophobicContact CE2-CG1 4.41Å; F37-V64 HydrophobicContact CG-CG1 4.4Å; F37-V64 HydrophobicContact CG-CG2 4Å; F37-V67 HydrophobicContact CE1-CG2 4.45Å; F37-V67 HydrophobicContact CE2-CG1 4.29Å; F37-V67 HydrophobicContact CZ-CB 3.79Å; F37-V67 HydrophobicContact CZ-CG1 3.62Å; F37-V67 HydrophobicContact CZ-CG2 4.1Å; F37-Y68 HydrophobicContact CD2-CE2 4.03Å; F37-Y68 HydrophobicContact CE2-CD2 4.23Å; F37-Y68 AromaticContact CE2-CE2 3.82Å; F37-Y68 HydrophobicContact CE2-CE2 3.82Å; F37-A81 WeakPolarHBondContact CD2-O 3.29Å; F37-A81 PolarHBondContact N-O 3.3Å; F37-L82 HydrophobicContact CB-CD1 3.77Å; F37-V83 PolarHBondContact O-N 2.86Å; F37-M164 HydrophobicContact CE1-SD 4.31Å; F37-F166 AromaticContact CD1-CE2 3.66Å; F37-F166 HydrophobicContact CD1-CE2 3.66Å; F37-F166 HydrophobicContact CD1-CZ 4.06Å; F37-F166 HydrophobicContact CE1-CE2 4.35Å; F37-F166 HydrophobicContact CE1-CZ 4.35Å
38L97.3Very high84.1Confident0 Ų048 Ų480%024%0.236CC..EExtended strand (participates in β ladder)trans-106.9107.6173.9-178.760.4000109.4V83 Y85 L140 A143 L144 L163 M164 I165 F166L38-V83 CarbonylContact C-O 3.57Å; L38-V83 WeakPolarHBondContact CA-O 3.46Å; L38-V83 HydrophobicContact CD1-CB 4Å; L38-V83 HydrophobicContact CD1-CG1 3.83Å; L38-Y85 HydrophobicContact CD1-CD1 3.66Å; L38-Y85 HydrophobicContact CD1-CE1 4.46Å; L38-Y85 HydrophobicContact CD1-CG 4.33Å; L38-Y85 HydrophobicContact CD2-CD1 4.45Å; L38-Y85 HydrophobicContact CG-CD1 3.77Å; L38-Y85 HydrophobicContact CG-CE1 4.09Å; L38-L140 HydrophobicContact CD2-CD1 4.07Å; L38-A143 HydrophobicContact CD1-CB 4.1Å; L38-A143 HydrophobicContact CD2-CB 4.26Å; L38-L144 HydrophobicContact CD2-CD2 4.39Å; L38-L163 HydrophobicContact CB-CD1 3.86Å; L38-L163 HydrophobicContact CD2-CD1 4.48Å; L38-M164 PolarHBondContact N-O 3.29Å; L38-I165 HydrophobicContact CD2-CG1 4.27Å; L38-I165 CarbonylContact O-C 3.59Å; L38-I165 WeakPolarHBondContact O-CA 3.35Å; L38-F166 PolarHBondContact O-N 3.31Å
39V96.9Very high85.7Confident0 Ų040 Ų400%021%0.212CC..EExtended strand (participates in β ladder)trans-112.5130.2-170.4-178.10000110.9F37 M45 F57 T60 M61 L82 V83 F84 Y85 F166F37-V39 HydrophobicContact CB-CG2 4.48Å; V39-M45 HydrophobicContact CG1-CE 4.41Å; V39-F57 HydrophobicContact CG1-CD2 4.33Å; V39-F57 HydrophobicContact CG1-CE2 4.3Å; V39-T60 HydrophobicContact CB-CG2 4.47Å; V39-T60 HydrophobicContact CG1-CG2 3.86Å; V39-T60 HydrophobicContact CG2-CG2 3.75Å; V39-M61 HydrophobicContact CB-CE 4.46Å; V39-M61 HydrophobicContact CG1-CE 4.03Å; V39-M61 HydrophobicContact CG2-CE 4Å; V39-L82 HydrophobicContact CG2-CD1 3.91Å; V39-V83 PolarHBondContact N-O 2.86Å; V39-F84 HydrophobicContact CB-CD1 3.7Å; V39-F84 HydrophobicContact CB-CE1 3.82Å; V39-F84 HydrophobicContact CG1-CD1 3.96Å; V39-F84 HydrophobicContact CG1-CE1 3.88Å; V39-F84 HydrophobicContact CG2-CE1 4.41Å; V39-F84 VanDerWaalsContact O-CA 3.29Å; V39-F84 WeakPolarHBondContact O-CA 3.48Å; V39-Y85 WeakPolarHBondContact O-CD1 3.47Å; V39-Y85 PolarHBondContact O-N 3.17Å; V39-F166 HydrophobicContact CG2-CB 4.32Å; V39-F166 HydrophobicContact CG2-CD2 4.25Å; V39-F166 HydrophobicContact CG2-CG 4.5Å
40D95.2Very high86.8Confident0 Ų043.3 Ų43.30%022%0.22CC..EExtended strand (participates in β ladder)trans-70.3126.3173.4-166.5-12000110.6S42 M45 Y85 F166 T167 R169D40-S42 WeakPolarHBondContact OD1-CB 3.45Å; D40-S42 PolarHBondContact OD1-N 2.86Å; D40-S42 PolarHBondContact OD1-OG 3.18Å; D40-M45 HydrophobicContact CB-CE 4.3Å; D40-M45 HydrophobicContact CB-CG 3.81Å; D40-M45 HydrophobicContact CB-SD 4.15Å; D40-M45 WeakPolarHBondContact O-CG 3.31Å; D40-Y85 VanDerWaalsContact CA-CE1 3.45Å; D40-Y85 HydrophobicContact CB-CE1 3.72Å; D40-Y85 HydrophobicContact CB-CE2 4.41Å; D40-Y85 WeakPolarHBondContact CB-OH 3.21Å; D40-Y85 PolarHBondContact OD2-OH 2.84Å; D40-F166 WeakPolarHBondContact CB-O 3.39Å; D40-F166 PolarHBondContact N-O 2.84Å; D40-T167 PolarHBondContact OD2-OG1 3.37Å; D40-R169 VanDerWaalsContact CG-NH2 3.27Å; D40-R169 IonicContact OD1-CZ 3.94Å; D40-R169 IonicContact OD1-NE 2.66Å; D40-R169 IonicContact OD1-NH2 3.52Å; D40-R169 PolarHBondContact OD1-NH2 3.25Å; D40-R169 IonicContact OD2-CZ 2.8Å; D40-R169 IonicContact OD2-NE 3.69Å; D40-R169 PolarHBondContact OD2-NE 3.35Å; D40-R169 IonicContact OD2-NH2 2.71Å; D40-R169 PolarHBondContact OD2-NH2 2.98Å
41A94Very high87.2Confident0 Ų047.8 Ų47.80%024%0.238CC..  trans-108.922.317700000112.4F46 F84 Y85 T87 S135A41-F46 WeakPolarHBondContact O-CE2 3.34Å; A41-F84 HydrophobicContact CB-CB 4.33Å; A41-Y85 PolarHBondContact N-O 3.05Å; A41-T87 HydrophobicContact CB-CG2 3.67Å; A41-S135 PolarHBondContact O-OG 3.42Å
42S91.2Very high87.2Confident8 Ų850.7 Ų50.76%0.05627%0.269CS..SBendtrans-71.2156.5174.5-57.80000112D40 E44 M45 F46 T138 R169D40-S42 WeakPolarHBondContact OD1-CB 3.45Å; D40-S42 PolarHBondContact OD1-N 2.86Å; D40-S42 PolarHBondContact OD1-OG 3.18Å; S42-E44 PolarHBondContact O-N 3.18Å; S42-M45 WeakPolarHBondContact O-CB 3.36Å; S42-M45 PolarHBondContact O-N 2.89Å; S42-F46 WeakPolarHBondContact O-CD2 3.31Å; S42-T138 WeakPolarHBondContact OG-CG2 3.46Å; S42-R169 PolarHBondContact OG-NE 3.49Å; S42-R169 PolarHBondContact OG-NH2 3.31Å
43K89.9Confident86.8Confident161 Ų16152.9 Ų52.970%0.728%0.281SS*.G310 helixtrans-52.7-35.4-175.7-64.8-178.9-179.5176.40113.4M45 F46K43-M45 VanDerWaalsContact C-N 3.28Å; K43-M45 PolarHBondContact O-N 2.69Å; K43-F46 PolarHBondContact O-N 3.22Å
44E89.3Confident86.6Confident90 Ų9054 Ų5442%0.42129%0.289SS..G310 helixtrans-63-30.5-179.7-65.6167.1-158.400113.6S42 F46 I47 R169S42-E44 PolarHBondContact O-N 3.18Å; E44-F46 PolarHBondContact O-N 3.08Å; E44-I47 HydrophobicContact CB-CD1 4.46Å; E44-I47 PolarHBondContact O-N 3.36Å; E44-R169 VanDerWaalsContact OE2-CD 3.23Å; E44-R169 WeakPolarHBondContact OE2-CD 3.41Å; E44-R169 WeakPolarHBondContact OE2-CG 3.46Å
45M90.9Very high86.5Confident0 Ų054.3 Ų54.30%029%0.291CS..G310 helixtrans-69-22.7178.3-70.5-76.3-67.900112.5V39 D40 S42 K43 N56 F57 C168 L202V39-M45 HydrophobicContact CG1-CE 4.41Å; D40-M45 HydrophobicContact CB-CE 4.3Å; D40-M45 HydrophobicContact CB-CG 3.81Å; D40-M45 HydrophobicContact CB-SD 4.15Å; D40-M45 WeakPolarHBondContact O-CG 3.31Å; S42-M45 WeakPolarHBondContact O-CB 3.36Å; S42-M45 PolarHBondContact O-N 2.89Å; K43-M45 VanDerWaalsContact C-N 3.28Å; K43-M45 PolarHBondContact O-N 2.69Å; M45-N56 HydrophobicContact CE-CB 4.34Å; M45-N56 PolarHBondContact O-N 3.4Å; M45-N56 HydrophobicContact SD-CB 4.02Å; M45-F57 HydrophobicContact CB-CB 4.24Å; M45-F57 VanDerWaalsContact O-CB 3.31Å; M45-F57 WeakPolarHBondContact O-CB 3.34Å; M45-F57 PolarHBondContact O-N 3.01Å; M45-C168 HydrophobicContact SD-CB 4.03Å; M45-C168 PolarHBondContact SD-N 3.1Å; M45-C168 VanDerWaalsContact SD-SG 3.61Å; M45-L202 HydrophobicContact CE-CD1 3.67Å; M45-L202 HydrophobicContact SD-CD1 4.01Å
46F90.4Very high86.4Confident48 Ų4854.8 Ų54.821%0.21129%0.294CS..G310 helixtrans-92.5-3.5-179.6-61.7-84.6000113.3A41 S42 K43 E44 K48 F57 A126 A129A41-F46 WeakPolarHBondContact O-CE2 3.34Å; S42-F46 WeakPolarHBondContact O-CD2 3.31Å; K43-F46 PolarHBondContact O-N 3.22Å; E44-F46 PolarHBondContact O-N 3.08Å; F46-K48 PolarHBondContact O-N 3.05Å; F46-F57 HydrophobicContact CD1-CB 4.01Å; F46-F57 HydrophobicContact CD1-CD1 4.14Å; F46-F57 AromaticContact CD1-CG 3.98Å; F46-F57 HydrophobicContact CD1-CG 3.98Å; F46-F57 HydrophobicContact CE1-CB 4.02Å; F46-F57 AromaticContact CE1-CD1 3.55Å; F46-F57 HydrophobicContact CE1-CD1 3.55Å; F46-F57 AromaticContact CE1-CD2 3.74Å; F46-F57 HydrophobicContact CE1-CD2 3.74Å; F46-F57 AromaticContact CE1-CE1 3.89Å; F46-F57 HydrophobicContact CE1-CE1 3.89Å; F46-F57 HydrophobicContact CE1-CE2 4.05Å; F46-F57 AromaticContact CE1-CG 3.47Å; F46-F57 HydrophobicContact CE1-CG 3.47Å; F46-F57 VanDerWaalsContact CE1-CG 3.47Å; F46-F57 HydrophobicContact CE1-CZ 4.12Å; F46-F57 HydrophobicContact CE2-CD2 4.4Å; F46-F57 HydrophobicContact CZ-CD1 4.3Å; F46-F57 AromaticContact CZ-CD2 3.65Å; F46-F57 HydrophobicContact CZ-CD2 3.65Å; F46-F57 HydrophobicContact CZ-CE1 4.45Å; F46-F57 AromaticContact CZ-CE2 3.82Å; F46-F57 HydrophobicContact CZ-CE2 3.82Å; F46-F57 AromaticContact CZ-CG 3.9Å; F46-F57 HydrophobicContact CZ-CG 3.9Å; F46-F57 HydrophobicContact CZ-CZ 4.23Å; F46-A126 HydrophobicContact CD1-CB 4.25Å; F46-A129 HydrophobicContact CE1-CB 3.95Å; F46-A129 HydrophobicContact CZ-CB 4.21Å
47I86.9Confident86.2Confident107 Ų10754.9 Ų54.955%0.54929%0.294SS..PPolyproline II helixtrans-68.2128.7175-59.2176000108.2E44 S55E44-I47 HydrophobicContact CB-CD1 4.46Å; E44-I47 PolarHBondContact O-N 3.36Å; I47-S55 WeakPolarHBondContact O-CA 3.1Å; I47-S55 WeakPolarHBondContact O-CB 3.23Å
48K82.6Confident86Confident118 Ų11855.7 Ų55.751%0.51330%0.299SS..BIsolated β-bridgetrans-77145175.1-66.4-175.1177.8-176.70110.1F46 E123F46-K48 PolarHBondContact O-N 3.05Å; K48-E123 IonicContact NZ-OE1 3.74Å; K48-E123 PolarHBondContact NZ-OE1 2.92Å
49G70.9Confident85.7Confident38 Ų3855.9 Ų55.939%0.39230%0.3SS..PPolyproline II helixtrans-66.1166.7169.900000112
50E68.8Low85.6Confident172 Ų17255.9 Ų55.980%0.80430%0.3SS*.G310 helixtrans-58.4153.1170.8-64.3-178.7170.500110.4G52 Q53E50-G52 VanDerWaalsContact C-N 3.34Å; E50-G52 PolarHBondContact O-N 3.03Å; E50-Q53 WeakPolarHBondContact O-CG 3.42Å; E50-Q53 PolarHBondContact O-N 2.64Å
51D62.4Low85.6Confident167 Ų16755.9 Ų55.989%0.89330%0.3SS*.G310 helixtrans58.232.6176.2-59.4-30.8000116.8Q53D51-Q53 VanDerWaalsContact C-N 3.3Å; D51-Q53 PolarHBondContact O-N 3.46Å
52G69.5Low85.5Confident72 Ų7257.9 Ų57.974%0.74231%0.309SS*.G310 helixtrans7715.3172.200000114.5E50E50-G52 VanDerWaalsContact C-N 3.34Å; E50-G52 PolarHBondContact O-N 3.03Å
53Q77.6Confident85.7Confident106 Ų10657.6 Ų57.650%0.49531%0.307SS..PPolyproline II helixtrans-58.8146.6169.5-68.9-67.8-27.400111.2E50 D51E50-Q53 WeakPolarHBondContact O-CG 3.42Å; E50-Q53 PolarHBondContact O-N 2.64Å; D51-Q53 VanDerWaalsContact C-N 3.3Å; D51-Q53 PolarHBondContact O-N 3.46Å
54P84.9Confident85.9Confident36 Ų3650 Ų5023%0.23427%0.274CS..PPolyproline II helixtrans-58.415317526-33.8000110.7D58 M59P54-D58 HydrophobicContact CB-CB 4.14Å; P54-D58 WeakPolarHBondContact CB-OD2 3.23Å; P54-M59 HydrophobicContact CB-CG 4.04Å; P54-M59 HydrophobicContact CG-CG 3.61Å; P54-M59 HydrophobicContact CG-SD 4.3Å
55S90.3Very high86.1Confident10 Ų1048.2 Ų48.27%0.0726%0.263CS..BIsolated β-bridgetrans-68.5159171.863.50000110.6I47 F57 D58 M59I47-S55 WeakPolarHBondContact O-CA 3.1Å; I47-S55 WeakPolarHBondContact O-CB 3.23Å; S55-F57 PolarHBondContact O-N 2.87Å; S55-D58 PolarHBondContact O-N 3.03Å; S55-D58 PolarHBondContact OG-N 2.89Å; S55-M59 PolarHBondContact O-N 2.91Å
56N91.3Very high86Confident18 Ų1849.3 Ų49.310%0.09627%0.271CS..Hα-helixtrans-53.3-37.8174.2-79.5-21.8000112.2M45 T60 C168 L202 I203M45-N56 HydrophobicContact CE-CB 4.34Å; M45-N56 PolarHBondContact O-N 3.4Å; M45-N56 HydrophobicContact SD-CB 4.02Å; N56-T60 WeakPolarHBondContact O-CB 3.32Å; N56-T60 PolarHBondContact O-N 3.25Å; N56-T60 PolarHBondContact O-OG1 3.32Å; N56-C168 WeakPolarHBondContact ND2-CB 3.4Å; N56-L202 HydrophobicContact CB-CB 4.32Å; N56-L202 HydrophobicContact CB-CD1 3.71Å; N56-I203 PolarHBondContact ND2-O 3.11Å
57F93.2Very high86.1Confident1 Ų147.2 Ų47.20%0.00426%0.262CS..Hα-helixtrans-64.5-48174.3-173.8-91.8000112.2V39 M45 F46 S55 T60 M61 F84 A129V39-F57 HydrophobicContact CG1-CD2 4.33Å; V39-F57 HydrophobicContact CG1-CE2 4.3Å; M45-F57 HydrophobicContact CB-CB 4.24Å; M45-F57 VanDerWaalsContact O-CB 3.31Å; M45-F57 WeakPolarHBondContact O-CB 3.34Å; M45-F57 PolarHBondContact O-N 3.01Å; F46-F57 HydrophobicContact CD1-CB 4.01Å; F46-F57 HydrophobicContact CD1-CD1 4.14Å; F46-F57 AromaticContact CD1-CG 3.98Å; F46-F57 HydrophobicContact CD1-CG 3.98Å; F46-F57 HydrophobicContact CE1-CB 4.02Å; F46-F57 AromaticContact CE1-CD1 3.55Å; F46-F57 HydrophobicContact CE1-CD1 3.55Å; F46-F57 AromaticContact CE1-CD2 3.74Å; F46-F57 HydrophobicContact CE1-CD2 3.74Å; F46-F57 AromaticContact CE1-CE1 3.89Å; F46-F57 HydrophobicContact CE1-CE1 3.89Å; F46-F57 HydrophobicContact CE1-CE2 4.05Å; F46-F57 AromaticContact CE1-CG 3.47Å; F46-F57 HydrophobicContact CE1-CG 3.47Å; F46-F57 VanDerWaalsContact CE1-CG 3.47Å; F46-F57 HydrophobicContact CE1-CZ 4.12Å; F46-F57 HydrophobicContact CE2-CD2 4.4Å; F46-F57 HydrophobicContact CZ-CD1 4.3Å; F46-F57 AromaticContact CZ-CD2 3.65Å; F46-F57 HydrophobicContact CZ-CD2 3.65Å; F46-F57 HydrophobicContact CZ-CE1 4.45Å; F46-F57 AromaticContact CZ-CE2 3.82Å; F46-F57 HydrophobicContact CZ-CE2 3.82Å; F46-F57 AromaticContact CZ-CG 3.9Å; F46-F57 HydrophobicContact CZ-CG 3.9Å; F46-F57 HydrophobicContact CZ-CZ 4.23Å; S55-F57 PolarHBondContact O-N 2.87Å; F57-T60 WeakPolarHBondContact O-CB 3.5Å; F57-T60 PolarHBondContact O-N 3.23Å; F57-T60 VanDerWaalsContact O-N 3.16Å; F57-M61 HydrophobicContact CD1-CG 3.98Å; F57-M61 HydrophobicContact CE1-CG 3.56Å; F57-M61 HydrophobicContact CE1-SD 4.29Å; F57-M61 HydrophobicContact CZ-CE 4.48Å; F57-M61 HydrophobicContact CZ-CG 3.94Å; F57-M61 HydrophobicContact CZ-SD 4.07Å; F57-M61 WeakPolarHBondContact O-CG 3.46Å; F57-M61 PolarHBondContact O-N 3.34Å; F57-F84 HydrophobicContact CE2-CD1 4.07Å; F57-F84 AromaticContact CE2-CE1 3.59Å; F57-F84 HydrophobicContact CE2-CE1 3.59Å; F57-F84 HydrophobicContact CE2-CZ 4.5Å; F57-F84 AromaticContact CZ-CE1 3.83Å; F57-F84 HydrophobicContact CZ-CE1 3.83Å; F57-F84 HydrophobicContact CZ-CZ 4.32Å; F57-A129 HydrophobicContact CE1-CB 3.96Å; F57-A129 HydrophobicContact CZ-CB 3.89Å
58D92.3Very high86.3Confident18 Ų1842.1 Ų42.110%0.09624%0.236CC..Hα-helixtrans-65.3-42.3179.9-176.635.3000111.6P54 S55 T60 M61 Q62 G122P54-D58 HydrophobicContact CB-CB 4.14Å; P54-D58 WeakPolarHBondContact CB-OD2 3.23Å; S55-D58 PolarHBondContact O-N 3.03Å; S55-D58 PolarHBondContact OG-N 2.89Å; D58-T60 VanDerWaalsContact C-N 3.27Å; D58-T60 PolarHBondContact O-N 2.92Å; D58-M61 PolarHBondContact O-N 3.16Å; D58-Q62 VanDerWaalsContact O-CG 3.31Å; D58-Q62 WeakPolarHBondContact O-CG 3.36Å; D58-Q62 PolarHBondContact O-N 2.9Å; D58-Q62 PolarHBondContact OD1-NE2 2.87Å; D58-Q62 PolarHBondContact OD2-NE2 3.31Å; D58-Q62 VanDerWaalsContact OD2-NE2 3.13Å; D58-G122 PolarHBondContact OD1-N 3.33Å
59M92Very high86.6Confident4 Ų438.2 Ų38.22%0.0222%0.222CC..Hα-helixtrans-53.7-47170.8-73.817746.700111.3P54 S55 Q62 V63 K236 L237 L240P54-M59 HydrophobicContact CB-CG 4.04Å; P54-M59 HydrophobicContact CG-CG 3.61Å; P54-M59 HydrophobicContact CG-SD 4.3Å; S55-M59 PolarHBondContact O-N 2.91Å; M59-Q62 PolarHBondContact O-N 2.78Å; M59-V63 WeakPolarHBondContact O-CG2 3Å; M59-V63 PolarHBondContact O-N 2.84Å; M59-V63 VanDerWaalsContact O-N 3.11Å; M59-K236 VanDerWaalsContact CE-C 3.47Å; M59-L237 HydrophobicContact CB-CD1 4.42Å; M59-L240 HydrophobicContact CB-CD2 4.27Å; M59-L240 HydrophobicContact CE-CD2 4.31Å
60T94.5Very high87.3Confident0 Ų038 Ų380%022%0.215CC..Hα-helixtrans-61.6-47.1179-58.40000111.5V39 N56 F57 D58 Q62 V63 V64 F166V39-T60 HydrophobicContact CB-CG2 4.47Å; V39-T60 HydrophobicContact CG1-CG2 3.86Å; V39-T60 HydrophobicContact CG2-CG2 3.75Å; N56-T60 WeakPolarHBondContact O-CB 3.32Å; N56-T60 PolarHBondContact O-N 3.25Å; N56-T60 PolarHBondContact O-OG1 3.32Å; F57-T60 WeakPolarHBondContact O-CB 3.5Å; F57-T60 PolarHBondContact O-N 3.23Å; F57-T60 VanDerWaalsContact O-N 3.16Å; D58-T60 VanDerWaalsContact C-N 3.27Å; D58-T60 PolarHBondContact O-N 2.92Å; T60-Q62 VanDerWaalsContact C-N 3.32Å; T60-Q62 PolarHBondContact O-N 3.46Å; T60-V63 PolarHBondContact O-N 2.79Å; T60-V63 VanDerWaalsContact O-N 3.16Å; T60-V64 HydrophobicContact CG2-CG2 4.29Å; T60-V64 WeakPolarHBondContact O-CG2 2.76Å; T60-V64 PolarHBondContact O-N 3.02Å; T60-F166 HydrophobicContact CG2-CB 3.74Å; T60-F166 HydrophobicContact CG2-CD1 3.52Å; T60-F166 HydrophobicContact CG2-CD2 4.27Å; T60-F166 HydrophobicContact CG2-CE1 4.16Å; T60-F166 HydrophobicContact CG2-CG 3.57Å
61M95.3Very high88.2Confident0 Ų030 Ų300%018%0.177CC..Hα-helixtrans-63.7-36.2179.1-66.9-57.895.200112.6V39 F57 D58 V63 V64 R65 L82 F84 L120 R121V39-M61 HydrophobicContact CB-CE 4.46Å; V39-M61 HydrophobicContact CG1-CE 4.03Å; V39-M61 HydrophobicContact CG2-CE 4Å; F57-M61 HydrophobicContact CD1-CG 3.98Å; F57-M61 HydrophobicContact CE1-CG 3.56Å; F57-M61 HydrophobicContact CE1-SD 4.29Å; F57-M61 HydrophobicContact CZ-CE 4.48Å; F57-M61 HydrophobicContact CZ-CG 3.94Å; F57-M61 HydrophobicContact CZ-SD 4.07Å; F57-M61 WeakPolarHBondContact O-CG 3.46Å; F57-M61 PolarHBondContact O-N 3.34Å; D58-M61 PolarHBondContact O-N 3.16Å; M61-V63 VanDerWaalsContact C-N 3.35Å; M61-V63 PolarHBondContact O-N 3.2Å; M61-V64 HydrophobicContact CE-CG2 4.21Å; M61-V64 PolarHBondContact O-N 3.46Å; M61-R65 WeakPolarHBondContact O-CB 3.24Å; M61-R65 PolarHBondContact O-N 2.6Å; M61-L82 HydrophobicContact CE-CD1 4.47Å; M61-F84 HydrophobicContact CE-CE1 3.81Å; M61-F84 HydrophobicContact CE-CZ 4.04Å; M61-F84 HydrophobicContact SD-CE1 4.16Å; M61-F84 HydrophobicContact SD-CZ 3.91Å; M61-L120 HydrophobicContact CG-CB 4.08Å; M61-L120 HydrophobicContact SD-CB 4.08Å; M61-L120 HydrophobicContact SD-CD1 4.09Å; M61-R121 HydrophobicContact CB-CG 4.01Å
62Q92.4Very high89.4Confident42 Ų4224.2 Ų24.220%0.19615%0.146CC..Hα-helixtrans-62-41.6173.3-71.8-175.54800112.2D58 M59 T60 S66 R121 L237D58-Q62 VanDerWaalsContact O-CG 3.31Å; D58-Q62 WeakPolarHBondContact O-CG 3.36Å; D58-Q62 PolarHBondContact O-N 2.9Å; D58-Q62 PolarHBondContact OD1-NE2 2.87Å; D58-Q62 PolarHBondContact OD2-NE2 3.31Å; D58-Q62 VanDerWaalsContact OD2-NE2 3.13Å; M59-Q62 PolarHBondContact O-N 2.78Å; T60-Q62 VanDerWaalsContact C-N 3.32Å; T60-Q62 PolarHBondContact O-N 3.46Å; Q62-S66 PolarHBondContact O-N 2.96Å; Q62-R121 HydrophobicContact CG-CG 4.41Å; Q62-L237 HydrophobicContact CB-CD1 3.86Å
63V93.4Very high90Very high2 Ų223.7 Ų23.71%0.01213%0.125CC..Hα-helixtrans-69.6-44.2176.4179.90000111.7M59 T60 M61 R65 S66 V67 L237 L240 Q241 V244M59-V63 WeakPolarHBondContact O-CG2 3Å; M59-V63 PolarHBondContact O-N 2.84Å; M59-V63 VanDerWaalsContact O-N 3.11Å; T60-V63 PolarHBondContact O-N 2.79Å; T60-V63 VanDerWaalsContact O-N 3.16Å; M61-V63 VanDerWaalsContact C-N 3.35Å; M61-V63 PolarHBondContact O-N 3.2Å; V63-R65 VanDerWaalsContact C-N 3.32Å; V63-R65 PolarHBondContact O-N 3.46Å; V63-S66 WeakPolarHBondContact O-CB 3.37Å; V63-S66 PolarHBondContact O-N 3.02Å; V63-S66 VanDerWaalsContact O-N 3.11Å; V63-V67 HydrophobicContact CG1-CG2 4.49Å; V63-V67 WeakPolarHBondContact O-CG2 3.33Å; V63-V67 PolarHBondContact O-N 3.29Å; V63-L237 HydrophobicContact CG2-CD1 3.72Å; V63-L240 HydrophobicContact CB-CD2 4.48Å; V63-L240 HydrophobicContact CG2-CB 4.28Å; V63-L240 HydrophobicContact CG2-CD2 3.76Å; V63-L240 HydrophobicContact CG2-CG 3.84Å; V63-Q241 HydrophobicContact CG2-CG 3.61Å; V63-V244 HydrophobicContact CG1-CB 3.7Å; V63-V244 HydrophobicContact CG1-CG1 3.79Å; V63-V244 HydrophobicContact CG1-CG2 3.68Å
64V94.7Very high90.1Very high0 Ų022.3 Ų22.30%013%0.127CC..Hα-helixtrans-57.9-45.6176.2175.20000110.5F37 T60 M61 S66 V67 Y68 L82 V117F37-V64 HydrophobicContact CB-CG2 4.36Å; F37-V64 HydrophobicContact CD1-CG2 3.82Å; F37-V64 HydrophobicContact CD2-CG1 4.2Å; F37-V64 HydrophobicContact CE1-CG2 4.25Å; F37-V64 HydrophobicContact CE2-CG1 4.41Å; F37-V64 HydrophobicContact CG-CG1 4.4Å; F37-V64 HydrophobicContact CG-CG2 4Å; T60-V64 HydrophobicContact CG2-CG2 4.29Å; T60-V64 WeakPolarHBondContact O-CG2 2.76Å; T60-V64 PolarHBondContact O-N 3.02Å; M61-V64 HydrophobicContact CE-CG2 4.21Å; M61-V64 PolarHBondContact O-N 3.46Å; V64-S66 PolarHBondContact O-N 2.9Å; V64-V67 PolarHBondContact O-N 2.74Å; V64-Y68 HydrophobicContact CG1-CD2 3.89Å; V64-Y68 HydrophobicContact CG1-CE2 3.7Å; V64-Y68 VanDerWaalsContact O-CD2 3.24Å; V64-Y68 WeakPolarHBondContact O-CD2 3.46Å; V64-Y68 PolarHBondContact O-N 3.23Å; V64-L82 HydrophobicContact CG1-CD1 4.34Å; V64-L82 HydrophobicContact CG1-CD2 4.41Å; V64-V117 HydrophobicContact CB-CG1 4.24Å; V64-V117 HydrophobicContact CG1-CG1 3.98Å; V64-V117 HydrophobicContact CG1-CG2 4.25Å
65R93.3Very high89.8Confident53 Ų5321.7 Ų21.720%0.212%0.124CC..Hα-helixtrans-57.3-48.2174.3-175-163.6178.1-147.25.9111.3M61 V63 V67 Y68 T69 V114 V117 D118M61-R65 WeakPolarHBondContact O-CB 3.24Å; M61-R65 PolarHBondContact O-N 2.6Å; V63-R65 VanDerWaalsContact C-N 3.32Å; V63-R65 PolarHBondContact O-N 3.46Å; R65-V67 VanDerWaalsContact C-N 3.29Å; R65-V67 PolarHBondContact O-N 2.95Å; R65-Y68 PolarHBondContact O-N 2.86Å; R65-T69 PolarHBondContact O-N 3.02Å; R65-T69 PolarHBondContact O-OG1 3.36Å; R65-V114 HydrophobicContact CG-CG1 4.35Å; R65-V117 HydrophobicContact CB-CG1 4.02Å; R65-D118 WeakPolarHBondContact CD-OD1 3.39Å; R65-D118 IonicContact CZ-OD1 3.58Å; R65-D118 VanDerWaalsContact CZ-OD1 3.32Å; R65-D118 IonicContact NE-OD1 3.53Å; R65-D118 PolarHBondContact NE-OD1 3.38Å; R65-D118 IonicContact NH1-OD1 3.65Å; R65-D118 IonicContact NH2-OD1 3.92Å
66S90.2Very high89.4Confident24 Ų2426.1 Ų26.117%0.16814%0.143CC..Hα-helixtrans-59.4-40.3-180-176.40000111.7Q62 V63 V64 T69 S70Q62-S66 PolarHBondContact O-N 2.96Å; V63-S66 WeakPolarHBondContact O-CB 3.37Å; V63-S66 PolarHBondContact O-N 3.02Å; V63-S66 VanDerWaalsContact O-N 3.11Å; V64-S66 PolarHBondContact O-N 2.9Å; S66-T69 PolarHBondContact O-OG1 3.12Å; S66-S70 VanDerWaalsContact O-CB 3.26Å; S66-S70 WeakPolarHBondContact O-CB 3.39Å; S66-S70 PolarHBondContact O-N 3.48Å; S66-S70 PolarHBondContact O-OG 3.39Å
67V91.4Very high89.1Confident3 Ų331.9 Ų31.92%0.01816%0.164CC..Hα-helixtrans-67.2-44.7175.8176.50000111.4L35 F37 V63 V64 R65 T69 S70 K71 V244 E248L35-V67 HydrophobicContact CD2-CG1 4.06Å; F37-V67 HydrophobicContact CE1-CG2 4.45Å; F37-V67 HydrophobicContact CE2-CG1 4.29Å; F37-V67 HydrophobicContact CZ-CB 3.79Å; F37-V67 HydrophobicContact CZ-CG1 3.62Å; F37-V67 HydrophobicContact CZ-CG2 4.1Å; V63-V67 HydrophobicContact CG1-CG2 4.49Å; V63-V67 WeakPolarHBondContact O-CG2 3.33Å; V63-V67 PolarHBondContact O-N 3.29Å; V64-V67 PolarHBondContact O-N 2.74Å; R65-V67 VanDerWaalsContact C-N 3.29Å; R65-V67 PolarHBondContact O-N 2.95Å; V67-T69 VanDerWaalsContact C-N 3.34Å; V67-T69 PolarHBondContact O-N 3.18Å; V67-S70 PolarHBondContact O-N 3.05Å; V67-S70 VanDerWaalsContact O-N 3.16Å; V67-K71 HydrophobicContact CG1-CG 4.06Å; V67-K71 WeakPolarHBondContact O-CB 3.42Å; V67-K71 WeakPolarHBondContact O-CG 3.38Å; V67-K71 PolarHBondContact O-N 3.37Å; V67-V244 HydrophobicContact CG2-CG1 3.58Å; V67-E248 HydrophobicContact CG1-CG 3.89Å
68Y91.8Very high89Confident0 Ų032.4 Ų32.40%017%0.167CC..Hα-helixtrans-56.9-46.8177.2-89.1-122.4000111.7F37 V64 R65 K71 I72 V80 H104 P109 R113F37-Y68 HydrophobicContact CD2-CE2 4.03Å; F37-Y68 HydrophobicContact CE2-CD2 4.23Å; F37-Y68 AromaticContact CE2-CE2 3.82Å; F37-Y68 HydrophobicContact CE2-CE2 3.82Å; V64-Y68 HydrophobicContact CG1-CD2 3.89Å; V64-Y68 HydrophobicContact CG1-CE2 3.7Å; V64-Y68 VanDerWaalsContact O-CD2 3.24Å; V64-Y68 WeakPolarHBondContact O-CD2 3.46Å; V64-Y68 PolarHBondContact O-N 3.23Å; R65-Y68 PolarHBondContact O-N 2.86Å; Y68-K71 PolarHBondContact O-N 2.96Å; Y68-I72 WeakPolarHBondContact O-CG1 3.32Å; Y68-I72 PolarHBondContact O-N 2.87Å; Y68-I72 VanDerWaalsContact O-N 3.13Å; Y68-V80 HydrophobicContact CD1-CG2 4.12Å; Y68-V80 HydrophobicContact CD2-CG2 4.34Å; Y68-V80 HydrophobicContact CE1-CG2 3.62Å; Y68-V80 HydrophobicContact CE2-CB 4.04Å; Y68-V80 HydrophobicContact CE2-CG2 3.9Å; Y68-V80 HydrophobicContact CG-CG2 4.46Å; Y68-H104 AromaticContact CE1-ND1 3.71Å; Y68-H104 AromaticContact CZ-ND1 3.77Å; Y68-H104 PolarHBondContact OH-ND1 3.45Å; Y68-H104 VanDerWaalsContact OH-ND1 3.16Å; Y68-P109 HydrophobicContact CD1-CB 4.24Å; Y68-R113 HydrophobicContact CD1-CB 4.12Å; Y68-R113 HydrophobicContact CE1-CB 3.83Å
69T88.4Confident89Confident37 Ų3731.6 Ų31.623%0.22716%0.162CC..Hα-helixtrans-65.5-40.1177.353.90000111.6R65 S66 V67 K71 I72 I73 V114R65-T69 PolarHBondContact O-N 3.02Å; R65-T69 PolarHBondContact O-OG1 3.36Å; S66-T69 PolarHBondContact O-OG1 3.12Å; V67-T69 VanDerWaalsContact C-N 3.34Å; V67-T69 PolarHBondContact O-N 3.18Å; T69-K71 PolarHBondContact O-N 2.8Å; T69-I72 PolarHBondContact O-N 2.61Å; T69-I73 WeakPolarHBondContact O-CG1 3.38Å; T69-I73 PolarHBondContact O-N 3.21Å; T69-V114 HydrophobicContact CG2-CG1 3.88Å; T69-V114 HydrophobicContact CG2-CG2 4.25Å
70S86.1Confident89.2Confident33 Ų3331.4 Ų31.423%0.23116%0.161CC..Hα-helixtrans-67.5-37.1-179.7-570000111.9S66 V67 I73 S74S66-S70 VanDerWaalsContact O-CB 3.26Å; S66-S70 WeakPolarHBondContact O-CB 3.39Å; S66-S70 PolarHBondContact O-N 3.48Å; S66-S70 PolarHBondContact O-OG 3.39Å; V67-S70 PolarHBondContact O-N 3.05Å; V67-S70 VanDerWaalsContact O-N 3.16Å; S70-I73 PolarHBondContact O-N 3.49Å; S70-S74 WeakPolarHBondContact O-CB 3.4Å; S70-S74 PolarHBondContact O-N 3.31Å; S70-S74 PolarHBondContact O-OG 3.22Å
71K87.9Confident89.2Confident4 Ų431.4 Ų31.42%0.01716%0.161CC..Hα-helixtrans-65.8-38.6172.9-72.8-63-167-172.80112.3V67 Y68 T69 I73 S74 S75 H76 D78 V80 P109 E248V67-K71 HydrophobicContact CG1-CG 4.06Å; V67-K71 WeakPolarHBondContact O-CB 3.42Å; V67-K71 WeakPolarHBondContact O-CG 3.38Å; V67-K71 PolarHBondContact O-N 3.37Å; Y68-K71 PolarHBondContact O-N 2.96Å; T69-K71 PolarHBondContact O-N 2.8Å; K71-I73 VanDerWaalsContact C-N 3.26Å; K71-I73 PolarHBondContact O-N 3.13Å; K71-S74 PolarHBondContact O-N 3.45Å; K71-S75 CarbonylContact O-C 3.55Å; K71-S75 WeakPolarHBondContact O-CA 3.45Å; K71-S75 PolarHBondContact O-N 3.08Å; K71-H76 WeakPolarHBondContact O-CA 3.4Å; K71-H76 PolarHBondContact O-N 3.12Å; K71-D78 HydrophobicContact CD-CB 4.18Å; K71-D78 IonicContact NZ-OD2 3.08Å; K71-D78 PolarHBondContact NZ-OD2 3.45Å; K71-V80 HydrophobicContact CG-CG1 4.37Å; K71-P109 HydrophobicContact CB-CG 3.95Å; K71-E248 WeakPolarHBondContact CD-OE1 3.37Å; K71-E248 WeakPolarHBondContact CE-OE1 3.43Å; K71-E248 IonicContact NZ-OE1 3.8Å
72I87.1Confident89.3Confident46 Ų4631.4 Ų31.424%0.23616%0.161CC..Hα-helixtrans-59.8-41174.1-68.1166.7000110.7Y68 T69 P109 V114 F485Y68-I72 WeakPolarHBondContact O-CG1 3.32Å; Y68-I72 PolarHBondContact O-N 2.87Å; Y68-I72 VanDerWaalsContact O-N 3.13Å; T69-I72 PolarHBondContact O-N 2.61Å; I72-P109 HydrophobicContact CD1-CB 4.35Å; I72-P109 HydrophobicContact CG1-CB 3.84Å; I72-P109 HydrophobicContact CG1-CG 3.89Å; I72-V114 HydrophobicContact CD1-CG2 3.7Å; I72-F485 HydrophobicContact CG2-CD1 4.11Å; I72-F485 HydrophobicContact CG2-CE1 4.16Å
73I82.9Confident89.6Confident61 Ų6129.4 Ų29.431%0.31315%0.152SC..Hα-helixtrans-72.8-46-179-62.9170.8000111.7T69 S70 K71 F485T69-I73 WeakPolarHBondContact O-CG1 3.38Å; T69-I73 PolarHBondContact O-N 3.21Å; S70-I73 PolarHBondContact O-N 3.49Å; K71-I73 VanDerWaalsContact C-N 3.26Å; K71-I73 PolarHBondContact O-N 3.13Å; I73-F485 HydrophobicContact CB-CD2 4.43Å; I73-F485 HydrophobicContact CB-CE2 4.05Å; I73-F485 HydrophobicContact CB-CZ 4.13Å; I73-F485 HydrophobicContact CD1-CD2 4.27Å; I73-F485 HydrophobicContact CG1-CD1 4.13Å; I73-F485 HydrophobicContact CG1-CD2 3.66Å; I73-F485 HydrophobicContact CG1-CE1 4.21Å; I73-F485 HydrophobicContact CG1-CE2 3.78Å; I73-F485 HydrophobicContact CG1-CG 3.87Å; I73-F485 HydrophobicContact CG1-CZ 4.05Å; I73-F485 HydrophobicContact CG2-CD2 4.32Å; I73-F485 HydrophobicContact CG2-CE2 3.73Å; I73-F485 HydrophobicContact CG2-CZ 4.14Å
74S79.2Confident89.7Confident76 Ų7629.3 Ų29.353%0.53115%0.151SC..Hα-helixtrans-103.5-28.9-165.765.90000114.7S70 K71S70-S74 WeakPolarHBondContact O-CB 3.4Å; S70-S74 PolarHBondContact O-N 3.31Å; S70-S74 PolarHBondContact O-OG 3.22Å; K71-S74 PolarHBondContact O-N 3.45Å
75S78.8Confident89.7Confident23 Ų2329.3 Ų29.316%0.16115%0.151CC..  trans-158.158.3-168.6-64.80000111.9K71 R77 D78K71-S75 CarbonylContact O-C 3.55Å; K71-S75 WeakPolarHBondContact O-CA 3.45Å; K71-S75 PolarHBondContact O-N 3.08Å; S75-R77 PolarHBondContact O-N 2.76Å; S75-D78 VanDerWaalsContact CB-OD2 3.26Å; S75-D78 WeakPolarHBondContact CB-OD2 3.26Å; S75-D78 WeakPolarHBondContact O-CB 3.44Å; S75-D78 PolarHBondContact O-N 2.94Å
76H81.3Confident89.7Confident104 Ų10426.8 Ų26.848%0.48114%0.142SC..THydrogen-bonded Turntrans-59.5-16.4-172.866.3-87.1000115.3K71K71-H76 WeakPolarHBondContact O-CA 3.4Å; K71-H76 PolarHBondContact O-N 3.12Å
77R85.7Confident89.8Confident139 Ų13925.7 Ų25.753%0.52513%0.134SC..THydrogen-bonded Turntrans-87-10.3178.6-61.9-173.5177.5172.61.4113.8R32 S75R32-R77 WeakPolarHBondContact CD-O 3.24Å; R32-R77 WeakPolarHBondContact CG-O 3.49Å; S75-R77 PolarHBondContact O-N 2.76Å
78D89.6Confident89.9Confident12 Ų1231.4 Ų31.46%0.06416%0.161CC..SBendtrans-68.5145.8175.6-69-7.5000109.4D33 K71 S75 P109D33-D78 HydrophobicContact CB-CB 4.5Å; D33-D78 CarbonylContact O-C 3.54Å; D33-D78 WeakPolarHBondContact O-CA 3.35Å; K71-D78 HydrophobicContact CD-CB 4.18Å; K71-D78 IonicContact NZ-OD2 3.08Å; K71-D78 PolarHBondContact NZ-OD2 3.45Å; S75-D78 VanDerWaalsContact CB-OD2 3.26Å; S75-D78 WeakPolarHBondContact CB-OD2 3.26Å; S75-D78 WeakPolarHBondContact O-CB 3.44Å; S75-D78 PolarHBondContact O-N 2.94Å; D78-P109 VanDerWaalsContact O-CD 3.26Å; D78-P109 WeakPolarHBondContact O-CD 3.41Å
79L93.4Very high89.8Confident1 Ų136.2 Ų36.21%0.00518%0.183CC..EExtended strand (participates in β ladder)trans-96.8131.8-179.7-50.7-175.2000110R32 D33 S34 L35 L106 D107 E108 I154 L156 L158R32-L79 HydrophobicContact CB-CG 4.45Å; D33-L79 PolarHBondContact O-N 2.82Å; S34-L79 WeakPolarHBondContact CA-O 3.44Å; L35-L79 PolarHBondContact N-O 3.49Å; L79-L106 HydrophobicContact CB-CD1 3.64Å; L79-L106 HydrophobicContact CB-CG 3.78Å; L79-L106 HydrophobicContact CD1-CG 4.23Å; L79-D107 CarbonylContact C-O 3.55Å; L79-D107 WeakPolarHBondContact CA-O 3.47Å; L79-E108 HydrophobicContact CD2-CG 4.05Å; L79-I154 HydrophobicContact CD1-CD1 4.17Å; L79-I154 HydrophobicContact CD1-CG1 4.24Å; L79-I154 HydrophobicContact CD1-CG2 3.89Å; L79-L156 HydrophobicContact CD1-CD1 4.38Å; L79-L158 HydrophobicContact CD1-CD2 3.87Å
80V95Very high89.9Confident0 Ų036.2 Ų36.20%019%0.185CC..EExtended strand (participates in β ladder)trans-122.7139.6177.3-650000110.8L35 Y68 K71 D107 P109 R113L35-V80 VanDerWaalsContact O-CA 3.32Å; L35-V80 WeakPolarHBondContact O-CA 3.33Å; Y68-V80 HydrophobicContact CD1-CG2 4.12Å; Y68-V80 HydrophobicContact CD2-CG2 4.34Å; Y68-V80 HydrophobicContact CE1-CG2 3.62Å; Y68-V80 HydrophobicContact CE2-CB 4.04Å; Y68-V80 HydrophobicContact CE2-CG2 3.9Å; Y68-V80 HydrophobicContact CG-CG2 4.46Å; K71-V80 HydrophobicContact CG-CG1 4.37Å; V80-D107 PolarHBondContact N-O 3.34Å; V80-D107 PolarHBondContact O-N 3.06Å; V80-P109 HydrophobicContact CG2-CB 3.92Å; V80-R113 PolarHBondContact O-NH1 3.17Å
81A96.3Very high90.2Very high0 Ų039.4 Ų39.40%019%0.194CC..EExtended strand (participates in β ladder)trans-128.8150.6173.500000110.6L35 V36 F37 H104 L106 L150L35-A81 PolarHBondContact O-N 3.4Å; V36-A81 HydrophobicContact CB-CB 4.44Å; V36-A81 HydrophobicContact CG1-CB 4.27Å; V36-A81 HydrophobicContact CG2-CB 4.04Å; F37-A81 WeakPolarHBondContact CD2-O 3.29Å; F37-A81 PolarHBondContact N-O 3.3Å; A81-H104 WeakPolarHBondContact CA-O 3.36Å; A81-H104 WeakPolarHBondContact CB-O 3.41Å; A81-L106 HydrophobicContact CB-CB 4.07Å; A81-L106 HydrophobicContact CB-CD1 3.93Å; A81-L150 HydrophobicContact CB-CD1 4.28Å
82L97.3Very high90.1Very high0 Ų039.9 Ų39.90%020%0.197CC..EExtended strand (participates in β ladder)trans-127116.6175179.260.1000109.2F37 V39 M61 V64 F84 Y103 H104 V117F37-L82 HydrophobicContact CB-CD1 3.77Å; V39-L82 HydrophobicContact CG2-CD1 3.91Å; M61-L82 HydrophobicContact CE-CD1 4.47Å; V64-L82 HydrophobicContact CG1-CD1 4.34Å; V64-L82 HydrophobicContact CG1-CD2 4.41Å; L82-F84 HydrophobicContact CD1-CE1 4.45Å; L82-F84 HydrophobicContact CD1-CE2 4.39Å; L82-F84 HydrophobicContact CD1-CZ 4.07Å; L82-F84 HydrophobicContact CD2-CE2 3.89Å; L82-F84 HydrophobicContact CD2-CZ 3.79Å; L82-F84 HydrophobicContact CG-CE2 3.84Å; L82-F84 HydrophobicContact CG-CZ 3.93Å; L82-Y103 HydrophobicContact CD2-CD1 3.95Å; L82-Y103 HydrophobicContact CD2-CG 4.47Å; L82-Y103 WeakPolarHBondContact O-CB 3.43Å; L82-Y103 PolarHBondContact O-N 3.05Å; L82-H104 HydrophobicContact CB-CB 4.17Å; L82-H104 PolarHBondContact N-O 3.4Å; L82-H104 PolarHBondContact O-N 2.92Å; L82-H104 VanDerWaalsContact O-N 3.09Å; L82-V117 HydrophobicContact CD2-CG2 3.9Å
83V96.9Very high89.4Confident0 Ų039.8 Ų39.80%020%0.196CC..EExtended strand (participates in β ladder)trans-124.4131.2-177.1-1740000108.7V36 F37 L38 V39 V100 V102 L150V36-V83 HydrophobicContact CG1-CG2 4.02Å; F37-V83 PolarHBondContact O-N 2.86Å; L38-V83 CarbonylContact C-O 3.57Å; L38-V83 WeakPolarHBondContact CA-O 3.46Å; L38-V83 HydrophobicContact CD1-CB 4Å; L38-V83 HydrophobicContact CD1-CG1 3.83Å; V39-V83 PolarHBondContact N-O 2.86Å; V83-V100 HydrophobicContact CG1-CG1 3.91Å; V83-V102 HydrophobicContact CG1-CG2 4.46Å; V83-V102 HydrophobicContact CG2-CG2 4.42Å; V83-L150 HydrophobicContact CG2-CD1 3.54Å
84F96.5Very high88.9Confident0 Ų048.3 Ų48.30%022%0.224CC..EExtended strand (participates in β ladder)trans-105144.2171.9-61.5-79.9000110.3V39 A41 F57 M61 L82 T87 Y101 Y103 L120 L133V39-F84 HydrophobicContact CB-CD1 3.7Å; V39-F84 HydrophobicContact CB-CE1 3.82Å; V39-F84 HydrophobicContact CG1-CD1 3.96Å; V39-F84 HydrophobicContact CG1-CE1 3.88Å; V39-F84 HydrophobicContact CG2-CE1 4.41Å; V39-F84 VanDerWaalsContact O-CA 3.29Å; V39-F84 WeakPolarHBondContact O-CA 3.48Å; A41-F84 HydrophobicContact CB-CB 4.33Å; F57-F84 HydrophobicContact CE2-CD1 4.07Å; F57-F84 AromaticContact CE2-CE1 3.59Å; F57-F84 HydrophobicContact CE2-CE1 3.59Å; F57-F84 HydrophobicContact CE2-CZ 4.5Å; F57-F84 AromaticContact CZ-CE1 3.83Å; F57-F84 HydrophobicContact CZ-CE1 3.83Å; F57-F84 HydrophobicContact CZ-CZ 4.32Å; M61-F84 HydrophobicContact CE-CE1 3.81Å; M61-F84 HydrophobicContact CE-CZ 4.04Å; M61-F84 HydrophobicContact SD-CE1 4.16Å; M61-F84 HydrophobicContact SD-CZ 3.91Å; L82-F84 HydrophobicContact CD1-CE1 4.45Å; L82-F84 HydrophobicContact CD1-CE2 4.39Å; L82-F84 HydrophobicContact CD1-CZ 4.07Å; L82-F84 HydrophobicContact CD2-CE2 3.89Å; L82-F84 HydrophobicContact CD2-CZ 3.79Å; L82-F84 HydrophobicContact CG-CE2 3.84Å; L82-F84 HydrophobicContact CG-CZ 3.93Å; F84-T87 HydrophobicContact CB-CG2 3.71Å; F84-Y101 PolarHBondContact N-O 3.24Å; F84-Y101 PolarHBondContact O-N 3.04Å; F84-Y103 HydrophobicContact CD2-CG 4.44Å; F84-Y103 HydrophobicContact CE2-CD2 4.09Å; F84-Y103 AromaticContact CE2-CG 3.84Å; F84-Y103 HydrophobicContact CE2-CG 3.84Å; F84-L120 HydrophobicContact CE2-CD1 4.23Å; F84-L120 HydrophobicContact CZ-CD1 3.92Å; F84-L133 HydrophobicContact CB-CD1 4.29Å; F84-L133 HydrophobicContact CD1-CD1 4.03Å; F84-L133 HydrophobicContact CD2-CD1 3.84Å; F84-L133 HydrophobicContact CD2-CD2 3.99Å; F84-L133 HydrophobicContact CE1-CD1 4.32Å; F84-L133 HydrophobicContact CE2-CD1 4.12Å; F84-L133 HydrophobicContact CG-CD1 3.78Å; F84-L133 HydrophobicContact CG-CD2 4.43Å; F84-L133 HydrophobicContact CZ-CD1 4.36Å
85Y95.2Very high88.8Confident0 Ų049.8 Ų49.80%023%0.226CC..EExtended strand (participates in β ladder)trans-131157172.576.7-80.6000111.4L38 V39 D40 A41 T87 H99 L140 A143 T167L38-Y85 HydrophobicContact CD1-CD1 3.66Å; L38-Y85 HydrophobicContact CD1-CE1 4.46Å; L38-Y85 HydrophobicContact CD1-CG 4.33Å; L38-Y85 HydrophobicContact CD2-CD1 4.45Å; L38-Y85 HydrophobicContact CG-CD1 3.77Å; L38-Y85 HydrophobicContact CG-CE1 4.09Å; V39-Y85 WeakPolarHBondContact O-CD1 3.47Å; V39-Y85 PolarHBondContact O-N 3.17Å; D40-Y85 VanDerWaalsContact CA-CE1 3.45Å; D40-Y85 HydrophobicContact CB-CE1 3.72Å; D40-Y85 HydrophobicContact CB-CE2 4.41Å; D40-Y85 WeakPolarHBondContact CB-OH 3.21Å; D40-Y85 PolarHBondContact OD2-OH 2.84Å; A41-Y85 PolarHBondContact N-O 3.05Å; Y85-T87 VanDerWaalsContact C-N 3.33Å; Y85-H99 CarbonylContact C-O 3.54Å; Y85-H99 WeakPolarHBondContact CA-O 3.33Å; Y85-L140 HydrophobicContact CD2-CD1 4.5Å; Y85-L140 HydrophobicContact CE1-CD1 4.46Å; Y85-L140 HydrophobicContact CE2-CD1 4.15Å; Y85-A143 HydrophobicContact CG-CB 4.15Å; Y85-T167 WeakPolarHBondContact OH-CB 3.19Å; Y85-T167 PolarHBondContact OH-OG1 3.41Å
86G92Very high88.9Confident0 Ų052.5 Ų52.50%024%0.244CC..SBendtrans76.824.4-169.800000112.7H99 S135 G136 T138G86-H99 PolarHBondContact N-O 3.1Å; G86-S135 WeakPolarHBondContact O-CA 3.25Å; G86-G136 PolarHBondContact O-N 3.27Å; G86-T138 VanDerWaalsContact CA-CG2 3.45Å
87T93.1Very high89.2Confident0 Ų048.1 Ų48.10%022%0.224CC..  trans-85.6154.9178.756.40000111A41 F84 Y85 Q89 H99 L133 G134A41-T87 HydrophobicContact CB-CG2 3.67Å; F84-T87 HydrophobicContact CB-CG2 3.71Å; Y85-T87 VanDerWaalsContact C-N 3.33Å; T87-Q89 WeakPolarHBondContact CB-O 3.48Å; T87-Q89 PolarHBondContact OG1-O 3.28Å; T87-H99 PolarHBondContact N-O 3.33Å; T87-H99 VanDerWaalsContact O-CA 3.23Å; T87-H99 WeakPolarHBondContact O-CA 3.4Å; T87-H99 VanDerWaalsContact O-CB 3.23Å; T87-H99 WeakPolarHBondContact O-CB 3.44Å; T87-H99 PolarHBondContact O-ND1 2.85Å; T87-H99 VanDerWaalsContact OG1-C 3.26Å; T87-H99 PolarHBondContact OG1-O 3.37Å; T87-L133 WeakPolarHBondContact CB-O 3.43Å; T87-L133 HydrophobicContact CG2-CB 3.8Å; T87-L133 HydrophobicContact CG2-CD2 4.37Å; T87-L133 HydrophobicContact CG2-CG 4.48Å; T87-G134 WeakPolarHBondContact CA-O 3.4Å
88E92.4Very high89.3Confident124 Ų12448.8 Ų48.858%0.57923%0.231SC*.SBendtrans-74.6-45.4169.6-173.6176.4-18000110.1L133 G134E88-L133 PolarHBondContact N-O 2.85Å; E88-G134 PolarHBondContact N-O 3.28Å
89Q90Very high89.5Confident100 Ų10050.6 Ų50.647%0.46724%0.239SC..SBendtrans-78.9145.8177-59.4-58.5-2800111.1T87 Y101 T132 L133T87-Q89 WeakPolarHBondContact CB-O 3.48Å; T87-Q89 PolarHBondContact OG1-O 3.28Å; Q89-Y101 HydrophobicContact CB-CD2 4.08Å; Q89-Y101 HydrophobicContact CB-CE2 4.21Å; Q89-T132 WeakPolarHBondContact CG-O 3.25Å; Q89-L133 PolarHBondContact N-O 2.62Å
90S91.9Very high89.5Confident38 Ų3850.6 Ų50.627%0.26624%0.239SC..  trans-120.6126.5177.9-540000110.1K98 H99S90-K98 WeakPolarHBondContact OG-CA 3.13Å; S90-H99 PolarHBondContact OG-N 2.89Å
91K91Very high89.5Confident100 Ų10052.2 Ų52.244%0.43525%0.245SC..BIsolated β-bridgetrans-141.999.7176.2-178.3-172.6175.6-166.50107.8V100 Y101 V102K91-V100 PolarHBondContact N-O 3.21Å; K91-Y101 HydrophobicContact CB-CD1 4.15Å; K91-Y101 HydrophobicContact CB-CD2 3.62Å; K91-Y101 HydrophobicContact CB-CE1 4.11Å; K91-Y101 HydrophobicContact CB-CE2 3.59Å; K91-Y101 HydrophobicContact CB-CG 3.9Å; K91-Y101 HydrophobicContact CD-CD1 4.3Å; K91-Y101 HydrophobicContact CD-CE1 3.58Å; K91-Y101 HydrophobicContact CD-CE2 4.1Å; K91-Y101 VanDerWaalsContact CD-CZ 3.46Å; K91-Y101 WeakPolarHBondContact CD-OH 3.23Å; K91-Y101 HydrophobicContact CG-CE1 4.46Å; K91-Y101 HydrophobicContact CG-CE2 4.5Å; K91-Y101 CarbonylContact O-C 3.57Å; K91-Y101 WeakPolarHBondContact O-CA 3.29Å; K91-V102 PolarHBondContact O-N 2.94Å
92N86.6Confident89.4Confident14 Ų1452.8 Ų52.88%0.07525%0.249CC..SBendtrans-149.5173.3177.348.566.7000110R94 N95 S96 F97 V100 V102N92-R94 PolarHBondContact O-N 2.88Å; N92-N95 PolarHBondContact N-OD1 3.34Å; N92-N95 PolarHBondContact O-N 3.1Å; N92-N95 PolarHBondContact O-OD1 3.2Å; N92-N95 VanDerWaalsContact OD1-C 3.29Å; N92-N95 WeakPolarHBondContact OD1-CA 3.22Å; N92-S96 PolarHBondContact OD1-N 2.93Å; N92-F97 PolarHBondContact ND2-O 3.2Å; N92-F97 PolarHBondContact OD1-N 3.36Å; N92-V100 PolarHBondContact ND2-O 3.21Å; N92-V102 HydrophobicContact CB-CG2 4.05Å
93Q71.8Confident89.3Confident44 Ų4454.9 Ų54.921%0.20626%0.257CS..G310 helixtrans-56118.9-178.5-69.6170.9-1400110N95 N149 D153Q93-N95 PolarHBondContact O-N 3.05Å; Q93-N149 VanDerWaalsContact OE1-CB 3.32Å; Q93-D153 PolarHBondContact NE2-OD2 3.17Å; Q93-D153 PolarHBondContact OE1-OD2 2.92Å; Q93-D153 VanDerWaalsContact OE1-OD2 3.08Å
94R72.3Confident89.3Confident240 Ų24055.5 Ų55.591%0.90626%0.26SS*.G310 helixtrans61.415.1-175.6-50177.5-177-179.81.6115.2N92 S96N92-R94 PolarHBondContact O-N 2.88Å; R94-S96 PolarHBondContact O-N 3.06Å; R94-S96 VanDerWaalsContact O-N 3.1Å; R94-S96 PolarHBondContact O-OG 3.44Å
95N77.4Confident89.1Confident107 Ų10759 Ų5957%0.57228%0.278SS*.G310 helixtrans47.337.6-177.5-87.5-0.1000113.6N92 Q93N92-N95 PolarHBondContact N-OD1 3.34Å; N92-N95 PolarHBondContact O-N 3.1Å; N92-N95 PolarHBondContact O-OD1 3.2Å; N92-N95 VanDerWaalsContact OD1-C 3.29Å; N92-N95 WeakPolarHBondContact OD1-CA 3.22Å; Q93-N95 PolarHBondContact O-N 3.05Å
96S80.7Confident89.1Confident79 Ų7959.3 Ų59.355%0.55228%0.28SS*.  trans-80.8-20.5-174.3-61.40000113.2N92 R94N92-S96 PolarHBondContact OD1-N 2.93Å; R94-S96 PolarHBondContact O-N 3.06Å; R94-S96 VanDerWaalsContact O-N 3.1Å; R94-S96 PolarHBondContact O-OG 3.44Å
97F87.6Confident89.2Confident12 Ų1263.2 Ų63.25%0.05330%0.301CS..SBendtrans-112.4132.8-178.2-53.4-60000111N92 V100 D142 W145 C146N92-F97 PolarHBondContact ND2-O 3.2Å; N92-F97 PolarHBondContact OD1-N 3.36Å; F97-V100 HydrophobicContact CB-CB 4.3Å; F97-V100 HydrophobicContact CB-CG2 4.23Å; F97-D142 HydrophobicContact CB-CB 4.15Å; F97-D142 HydrophobicContact CD1-CB 3.91Å; F97-D142 HydrophobicContact CG-CB 4.24Å; F97-W145 HydrophobicContact CD1-CE3 4.31Å; F97-W145 HydrophobicContact CE1-CB 4.46Å; F97-W145 AromaticContact CE1-CD2 3.62Å; F97-W145 HydrophobicContact CE1-CD2 3.62Å; F97-W145 AromaticContact CE1-CE3 3.2Å; F97-W145 HydrophobicContact CE1-CE3 3.2Å; F97-W145 HydrophobicContact CE1-CG 4.2Å; F97-W145 HydrophobicContact CE1-CH2 4.25Å; F97-W145 AromaticContact CE1-CZ3 3.56Å; F97-W145 HydrophobicContact CE1-CZ3 3.56Å; F97-W145 HydrophobicContact CZ-CB 4.22Å; F97-W145 AromaticContact CZ-CD2 3.44Å; F97-W145 HydrophobicContact CZ-CD2 3.44Å; F97-W145 VanDerWaalsContact CZ-CD2 3.44Å; F97-W145 AromaticContact CZ-CE2 3.85Å; F97-W145 AromaticContact CZ-CE3 3.58Å; F97-W145 HydrophobicContact CZ-CE3 3.58Å; F97-W145 AromaticContact CZ-CG 3.77Å; F97-W145 HydrophobicContact CZ-CG 3.77Å; F97-W145 HydrophobicContact CZ-CH2 4.39Å; F97-W145 HydrophobicContact CZ-CZ2 4.31Å; F97-W145 HydrophobicContact CZ-CZ3 4.06Å; F97-C146 HydrophobicContact CD2-CB 3.83Å; F97-C146 HydrophobicContact CE2-CB 4.17Å
98K89.3Confident89.1Confident154 Ų15466.5 Ų66.567%0.6732%0.317SS*.THydrogen-bonded Turntrans-84.8149.6173.1-66.5-173.4178.8-177.50110S90 V100S90-K98 WeakPolarHBondContact OG-CA 3.13Å; K98-V100 PolarHBondContact O-N 2.93Å
99H92.1Very high89.1Confident49 Ų4961.3 Ų61.323%0.22729%0.294CS..THydrogen-bonded Turntrans62.224.4175.7-48.3-63.7000115.2Y85 G86 T87 S90 E137Y85-H99 CarbonylContact C-O 3.54Å; Y85-H99 WeakPolarHBondContact CA-O 3.33Å; G86-H99 PolarHBondContact N-O 3.1Å; T87-H99 PolarHBondContact N-O 3.33Å; T87-H99 VanDerWaalsContact O-CA 3.23Å; T87-H99 WeakPolarHBondContact O-CA 3.4Å; T87-H99 VanDerWaalsContact O-CB 3.23Å; T87-H99 WeakPolarHBondContact O-CB 3.44Å; T87-H99 PolarHBondContact O-ND1 2.85Å; T87-H99 VanDerWaalsContact OG1-C 3.26Å; T87-H99 PolarHBondContact OG1-O 3.37Å; S90-H99 PolarHBondContact OG-N 2.89Å; H99-E137 WeakPolarHBondContact CB-O 3.38Å; H99-E137 VanDerWaalsContact CG-O 3.26Å
100V93.9Very high89.1Confident1 Ų157.9 Ų57.91%0.00629%0.285CS..EExtended strand (participates in β ladder)trans-126.3126.2175.5-177.90000109.2V83 K91 N92 F97 K98 D142 A143 C146V83-V100 HydrophobicContact CG1-CG1 3.91Å; K91-V100 PolarHBondContact N-O 3.21Å; N92-V100 PolarHBondContact ND2-O 3.21Å; F97-V100 HydrophobicContact CB-CB 4.3Å; F97-V100 HydrophobicContact CB-CG2 4.23Å; K98-V100 PolarHBondContact O-N 2.93Å; V100-D142 HydrophobicContact CG2-CB 4.41Å; V100-A143 HydrophobicContact CG2-CB 4.02Å; V100-C146 HydrophobicContact CG1-CB 3.87Å
101Y94.9Very high88.9Confident34 Ų3457 Ų5713%0.13328%0.28CS..EExtended strand (participates in β ladder)trans-125.2108.2-176.7-161.9-71000111F84 Q89 K91 Y103 L133F84-Y101 PolarHBondContact N-O 3.24Å; F84-Y101 PolarHBondContact O-N 3.04Å; Q89-Y101 HydrophobicContact CB-CD2 4.08Å; Q89-Y101 HydrophobicContact CB-CE2 4.21Å; K91-Y101 HydrophobicContact CB-CD1 4.15Å; K91-Y101 HydrophobicContact CB-CD2 3.62Å; K91-Y101 HydrophobicContact CB-CE1 4.11Å; K91-Y101 HydrophobicContact CB-CE2 3.59Å; K91-Y101 HydrophobicContact CB-CG 3.9Å; K91-Y101 HydrophobicContact CD-CD1 4.3Å; K91-Y101 HydrophobicContact CD-CE1 3.58Å; K91-Y101 HydrophobicContact CD-CE2 4.1Å; K91-Y101 VanDerWaalsContact CD-CZ 3.46Å; K91-Y101 WeakPolarHBondContact CD-OH 3.23Å; K91-Y101 HydrophobicContact CG-CE1 4.46Å; K91-Y101 HydrophobicContact CG-CE2 4.5Å; K91-Y101 CarbonylContact O-C 3.57Å; K91-Y101 WeakPolarHBondContact O-CA 3.29Å; Y101-Y103 HydrophobicContact CD1-CD2 4.39Å; Y101-Y103 AromaticContact CE1-CD2 3.98Å; Y101-Y103 HydrophobicContact CE1-CD2 3.98Å; Y101-Y103 PolarHBondContact O-N 3.05Å; Y101-L133 HydrophobicContact CD1-CD2 3.68Å; Y101-L133 HydrophobicContact CD2-CD2 3.99Å; Y101-L133 HydrophobicContact CE1-CD2 4.1Å; Y101-L133 HydrophobicContact CE2-CD2 4.37Å; Y101-L133 HydrophobicContact CG-CD2 3.64Å
102V95.4Very high88.8Confident13 Ų1359.3 Ų59.38%0.07929%0.29CS..EExtended strand (participates in β ladder)trans-78.2103.5170.1-177.20000107.9V83 K91 N92 L150V83-V102 HydrophobicContact CG1-CG2 4.46Å; V83-V102 HydrophobicContact CG2-CG2 4.42Å; K91-V102 PolarHBondContact O-N 2.94Å; N92-V102 HydrophobicContact CB-CG2 4.05Å; V102-L150 HydrophobicContact CG1-CD2 4.22Å; V102-L150 HydrophobicContact CG2-CD2 4.47Å
103Y95.3Very high89.2Confident44 Ų4460.7 Ų60.717%0.17329%0.294CS..EExtended strand (participates in β ladder)trans-80.3-51.3179.6-166.6-97000110.4L82 F84 Y101 D116 L120L82-Y103 HydrophobicContact CD2-CD1 3.95Å; L82-Y103 HydrophobicContact CD2-CG 4.47Å; L82-Y103 WeakPolarHBondContact O-CB 3.43Å; L82-Y103 PolarHBondContact O-N 3.05Å; F84-Y103 HydrophobicContact CD2-CG 4.44Å; F84-Y103 HydrophobicContact CE2-CD2 4.09Å; F84-Y103 AromaticContact CE2-CG 3.84Å; F84-Y103 HydrophobicContact CE2-CG 3.84Å; Y101-Y103 HydrophobicContact CD1-CD2 4.39Å; Y101-Y103 AromaticContact CE1-CD2 3.98Å; Y101-Y103 HydrophobicContact CE1-CD2 3.98Å; Y101-Y103 PolarHBondContact O-N 3.05Å; Y103-D116 HydrophobicContact CE1-CB 3.8Å; Y103-D116 PolarHBondContact OH-O 3.03Å; Y103-L120 HydrophobicContact CE1-CD1 4.05Å; Y103-L120 HydrophobicContact CE2-CD1 4.18Å
104H95.4Very high90.1Very high12 Ų1258.7 Ų58.76%0.05629%0.285CS..EExtended strand (participates in β ladder)trans-119.9126.3169-64.4155.5000110.3Y68 A81 L82 R113 D116Y68-H104 AromaticContact CE1-ND1 3.71Å; Y68-H104 AromaticContact CZ-ND1 3.77Å; Y68-H104 PolarHBondContact OH-ND1 3.45Å; Y68-H104 VanDerWaalsContact OH-ND1 3.16Å; A81-H104 WeakPolarHBondContact CA-O 3.36Å; A81-H104 WeakPolarHBondContact CB-O 3.41Å; L82-H104 HydrophobicContact CB-CB 4.17Å; L82-H104 PolarHBondContact N-O 3.4Å; L82-H104 PolarHBondContact O-N 2.92Å; L82-H104 VanDerWaalsContact O-N 3.09Å; H104-R113 PolarHBondContact CE1-O 2.74Å; H104-D116 IonicContact NE2-OD2 3.7Å
105D94.1Very high90.9Very high73 Ų7352.1 Ų52.139%0.3926%0.264SS..EExtended strand (participates in β ladder)trans-69.6161.7168.3-151.4-24.6000110.4D107 R113 L150D105-D107 PolarHBondContact O-N 3.4Å; D105-R113 PolarHBondContact O-NH1 2.96Å; D105-R113 PolarHBondContact O-NH2 2.97Å; D105-R113 VanDerWaalsContact O-NH2 3.16Å; D105-L150 VanDerWaalsContact OD1-CD2 3.26Å; D105-L150 WeakPolarHBondContact OD1-CD2 3.39Å
106L93.5Very high91.7Very high7 Ų750 Ų504%0.03725%0.253CS..EExtended strand (participates in β ladder)trans-69.1103.1-175.6-17160.5000110.5V36 L79 A81 Y151 I154V36-L106 HydrophobicContact CG2-CD1 4.33Å; L79-L106 HydrophobicContact CB-CD1 3.64Å; L79-L106 HydrophobicContact CB-CG 3.78Å; L79-L106 HydrophobicContact CD1-CG 4.23Å; A81-L106 HydrophobicContact CB-CB 4.07Å; A81-L106 HydrophobicContact CB-CD1 3.93Å; L106-Y151 HydrophobicContact CD2-CD1 3.88Å; L106-Y151 HydrophobicContact CD2-CE1 4.17Å; L106-I154 HydrophobicContact CB-CD1 4.11Å; L106-I154 HydrophobicContact CB-CG1 4.3Å; L106-I154 HydrophobicContact CD2-CD1 4.34Å; L106-I154 HydrophobicContact CD2-CG1 3.65Å; L106-I154 HydrophobicContact CG-CD1 4.25Å; L106-I154 HydrophobicContact CG-CG1 4.09Å; L106-I154 VanDerWaalsContact O-CD1 3.32Å; L106-I154 WeakPolarHBondContact O-CD1 3.48Å
107D93.9Very high92.3Very high83 Ų8346.3 Ų46.344%0.44423%0.227SC..EExtended strand (participates in β ladder)trans-156.2173.6-175.9-157.1-0.3000110.8L79 V80 D105 R113L79-D107 CarbonylContact C-O 3.55Å; L79-D107 WeakPolarHBondContact CA-O 3.47Å; V80-D107 PolarHBondContact N-O 3.34Å; V80-D107 PolarHBondContact O-N 3.06Å; D105-D107 PolarHBondContact O-N 3.4Å; D107-R113 VanDerWaalsContact CB-CZ 3.47Å; D107-R113 IonicContact OD2-NH2 3.36Å
108E92.5Very high92.4Very high69 Ų6948.5 Ų48.532%0.32224%0.239SC..  trans-58.5140.9175.6-65.3178.7-172.700111.3R32 L79R32-E108 IonicContact CZ-OE1 3.66Å; R32-E108 IonicContact NH1-OE1 3.66Å; R32-E108 PolarHBondContact NH1-OE1 2.94Å; R32-E108 IonicContact NH2-OE1 2.76Å; R32-E108 PolarHBondContact NH2-OE1 3.43Å; L79-E108 HydrophobicContact CD2-CG 4.05Å
109P91.6Very high92.6Very high15 Ų1543.4 Ų43.410%0.09723%0.226CC..  trans-66.6147.1173.430.7-36.1000110.1Y68 K71 I72 D78 V80Y68-P109 HydrophobicContact CD1-CB 4.24Å; K71-P109 HydrophobicContact CB-CG 3.95Å; I72-P109 HydrophobicContact CD1-CB 4.35Å; I72-P109 HydrophobicContact CG1-CB 3.84Å; I72-P109 HydrophobicContact CG1-CG 3.89Å; D78-P109 VanDerWaalsContact O-CD 3.26Å; D78-P109 WeakPolarHBondContact O-CD 3.41Å; V80-P109 HydrophobicContact CG2-CB 3.92Å
110G89.3Confident92.6Very high27 Ų2741.2 Ų41.228%0.27822%0.216SC..  trans-154.1166.8179.800000112.1K112 R113 V114G110-K112 VanDerWaalsContact C-N 3.34Å; G110-K112 PolarHBondContact O-N 2.82Å; G110-R113 PolarHBondContact O-N 3Å; G110-R113 VanDerWaalsContact O-N 3.1Å; G110-V114 PolarHBondContact O-N 3.14Å
111A88Confident92.5Very high20 Ų2044.7 Ų44.717%0.16523%0.229CC..Hα-helixtrans-58.5-42.6-17200000112.9R113 V114 Q115 A492 L493A111-R113 PolarHBondContact O-N 3.49Å; A111-V114 WeakPolarHBondContact O-CB 3.24Å; A111-V114 PolarHBondContact O-N 2.72Å; A111-Q115 PolarHBondContact O-N 3.19Å; A111-A492 HydrophobicContact CB-CB 3.62Å; A111-L493 HydrophobicContact CB-CD1 4.18Å; A111-L493 HydrophobicContact CB-CD2 3.75Å; A111-L493 HydrophobicContact CB-CG 3.73Å
112K90.1Very high92.2Very high149 Ų14944.5 Ų44.565%0.64824%0.237SC*.Hα-helixtrans-59.5-45.2175.8-68.3-177.6179.3178.60112.2G110 V114 Q115 D116 L493G110-K112 VanDerWaalsContact C-N 3.34Å; G110-K112 PolarHBondContact O-N 2.82Å; K112-V114 VanDerWaalsContact C-N 3.31Å; K112-V114 PolarHBondContact O-N 2.85Å; K112-Q115 CarbonylContact O-C 3.59Å; K112-Q115 WeakPolarHBondContact O-CB 3.47Å; K112-Q115 PolarHBondContact O-N 2.92Å; K112-Q115 VanDerWaalsContact O-N 3.12Å; K112-D116 PolarHBondContact O-N 2.77Å; K112-L493 HydrophobicContact CG-CD2 4.06Å
113R93.8Very high91.7Very high42 Ų4249.7 Ų49.716%0.15826%0.261CS..Hα-helixtrans-64.6-35.9177.5-65.6-178.1171.9-142.5-9.1112.1Y68 V80 H104 D105 D107 G110 A111 Q115 D116 V117Y68-R113 HydrophobicContact CD1-CB 4.12Å; Y68-R113 HydrophobicContact CE1-CB 3.83Å; V80-R113 PolarHBondContact O-NH1 3.17Å; H104-R113 PolarHBondContact CE1-O 2.74Å; D105-R113 PolarHBondContact O-NH1 2.96Å; D105-R113 PolarHBondContact O-NH2 2.97Å; D105-R113 VanDerWaalsContact O-NH2 3.16Å; D107-R113 VanDerWaalsContact CB-CZ 3.47Å; D107-R113 IonicContact OD2-NH2 3.36Å; G110-R113 PolarHBondContact O-N 3Å; G110-R113 VanDerWaalsContact O-N 3.1Å; A111-R113 PolarHBondContact O-N 3.49Å; R113-Q115 VanDerWaalsContact C-N 3.35Å; R113-D116 PolarHBondContact O-N 2.84Å; R113-V117 WeakPolarHBondContact O-CG2 3.43Å; R113-V117 PolarHBondContact O-N 2.69Å; R113-V117 VanDerWaalsContact O-N 3.1Å
114V91.2Very high91.3Very high3 Ų356.1 Ų56.12%0.01829%0.29CS..Hα-helixtrans-63-44.7173173.40000110.1R65 T69 I72 G110 A111 K112 V117 D118R65-V114 HydrophobicContact CG-CG1 4.35Å; T69-V114 HydrophobicContact CG2-CG1 3.88Å; T69-V114 HydrophobicContact CG2-CG2 4.25Å; I72-V114 HydrophobicContact CD1-CG2 3.7Å; G110-V114 PolarHBondContact O-N 3.14Å; A111-V114 WeakPolarHBondContact O-CB 3.24Å; A111-V114 PolarHBondContact O-N 2.72Å; K112-V114 VanDerWaalsContact C-N 3.31Å; K112-V114 PolarHBondContact O-N 2.85Å; V114-V117 PolarHBondContact O-N 3.49Å; V114-D118 WeakPolarHBondContact O-CB 3.23Å; V114-D118 PolarHBondContact O-N 3.37Å
115Q90.1Very high90.9Very high101 Ų10155.6 Ų55.647%0.47229%0.287SS..Hα-helixtrans-63.5-41.6177.1-171.6-179.316.800112.4A111 K112 R113 V117 D118 A119 L493A111-Q115 PolarHBondContact O-N 3.19Å; K112-Q115 CarbonylContact O-C 3.59Å; K112-Q115 WeakPolarHBondContact O-CB 3.47Å; K112-Q115 PolarHBondContact O-N 2.92Å; K112-Q115 VanDerWaalsContact O-N 3.12Å; R113-Q115 VanDerWaalsContact C-N 3.35Å; Q115-V117 PolarHBondContact O-N 3.16Å; Q115-D118 PolarHBondContact O-N 3.11Å; Q115-A119 WeakPolarHBondContact O-CB 3.48Å; Q115-A119 PolarHBondContact O-N 3.04Å; Q115-L493 HydrophobicContact CB-CD1 4.48Å
116D93.1Very high90.6Very high64 Ų6453.5 Ų53.534%0.34228%0.28SS..Hα-helixtrans-61.9-43.1177.9-64.6-29.1000111Y103 H104 K112 R113Y103-D116 HydrophobicContact CE1-CB 3.8Å; Y103-D116 PolarHBondContact OH-O 3.03Å; H104-D116 IonicContact NE2-OD2 3.7Å; K112-D116 PolarHBondContact O-N 2.77Å; R113-D116 PolarHBondContact O-N 2.84Å
117V92.9Very high90.4Very high0 Ų058.7 Ų58.70%030%0.304CS..Hα-helixtrans-68.1-38.9173.3177.50000111.4V64 R65 L82 R113 V114 Q115 A119 L120V64-V117 HydrophobicContact CB-CG1 4.24Å; V64-V117 HydrophobicContact CG1-CG1 3.98Å; V64-V117 HydrophobicContact CG1-CG2 4.25Å; R65-V117 HydrophobicContact CB-CG1 4.02Å; L82-V117 HydrophobicContact CD2-CG2 3.9Å; R113-V117 WeakPolarHBondContact O-CG2 3.43Å; R113-V117 PolarHBondContact O-N 2.69Å; R113-V117 VanDerWaalsContact O-N 3.1Å; V114-V117 PolarHBondContact O-N 3.49Å; Q115-V117 PolarHBondContact O-N 3.16Å; V117-A119 VanDerWaalsContact C-N 3.27Å; V117-A119 PolarHBondContact O-N 3.36Å; V117-L120 WeakPolarHBondContact O-CB 3.32Å; V117-L120 PolarHBondContact O-N 3.43Å; V117-L120 VanDerWaalsContact O-N 3.08Å
118D90.1Very high90.2Very high58 Ų5857.6 Ų57.631%0.3130%0.298SS..Hα-helixtrans-63.2-35.9178.9-162.162.6000111.8R65 V114 Q115 L120 R121R65-D118 WeakPolarHBondContact CD-OD1 3.39Å; R65-D118 IonicContact CZ-OD1 3.58Å; R65-D118 VanDerWaalsContact CZ-OD1 3.32Å; R65-D118 IonicContact NE-OD1 3.53Å; R65-D118 PolarHBondContact NE-OD1 3.38Å; R65-D118 IonicContact NH1-OD1 3.65Å; R65-D118 IonicContact NH2-OD1 3.92Å; V114-D118 WeakPolarHBondContact O-CB 3.23Å; V114-D118 PolarHBondContact O-N 3.37Å; Q115-D118 PolarHBondContact O-N 3.11Å; D118-L120 PolarHBondContact O-N 3.17Å; D118-R121 WeakPolarHBondContact O-CB 3.48Å; D118-R121 PolarHBondContact O-N 2.9Å; D118-R121 VanDerWaalsContact O-N 3.1Å; D118-R121 VanDerWaalsContact OD1-CD 3.29Å; D118-R121 WeakPolarHBondContact OD1-CD 3.45Å; D118-R121 IonicContact OD1-CZ 2.67Å; D118-R121 IonicContact OD1-NE 3.7Å; D118-R121 IonicContact OD1-NH1 2.61Å; D118-R121 PolarHBondContact OD1-NH1 2.86Å
119A93.1Very high90.1Very high48 Ų4854.3 Ų54.340%0.39728%0.283SS..THydrogen-bonded Turntrans-63.6-20.9174.700000113.6Q115 V117 R121 G125 L128Q115-A119 WeakPolarHBondContact O-CB 3.48Å; Q115-A119 PolarHBondContact O-N 3.04Å; V117-A119 VanDerWaalsContact C-N 3.27Å; V117-A119 PolarHBondContact O-N 3.36Å; A119-R121 VanDerWaalsContact C-N 3.33Å; A119-G125 WeakPolarHBondContact O-CA 3.33Å; A119-L128 HydrophobicContact CB-CD2 4.06Å
120L92.7Very high90Very high2 Ų256.5 Ų56.51%0.0130%0.302CS..THydrogen-bonded Turntrans-87.32.7176.6-63.9174.8000113.5M61 F84 Y103 V117 D118 G125 L128 A129M61-L120 HydrophobicContact CG-CB 4.08Å; M61-L120 HydrophobicContact SD-CB 4.08Å; M61-L120 HydrophobicContact SD-CD1 4.09Å; F84-L120 HydrophobicContact CE2-CD1 4.23Å; F84-L120 HydrophobicContact CZ-CD1 3.92Å; Y103-L120 HydrophobicContact CE1-CD1 4.05Å; Y103-L120 HydrophobicContact CE2-CD1 4.18Å; V117-L120 WeakPolarHBondContact O-CB 3.32Å; V117-L120 PolarHBondContact O-N 3.43Å; V117-L120 VanDerWaalsContact O-N 3.08Å; D118-L120 PolarHBondContact O-N 3.17Å; L120-G125 VanDerWaalsContact C-CA 3.43Å; L120-L128 HydrophobicContact CD2-CD2 4.13Å; L120-L128 HydrophobicContact CD2-CG 4.25Å; L120-A129 HydrophobicContact CD2-CB 4.23Å
121R91.9Very high90Very high74 Ų7462.6 Ų62.628%0.27932%0.324SS..SBendtrans-89154.1179.6-6417258.8-151.3-2.3113.6M61 Q62 D118 A119 G125M61-R121 HydrophobicContact CB-CG 4.01Å; Q62-R121 HydrophobicContact CG-CG 4.41Å; D118-R121 WeakPolarHBondContact O-CB 3.48Å; D118-R121 PolarHBondContact O-N 2.9Å; D118-R121 VanDerWaalsContact O-N 3.1Å; D118-R121 VanDerWaalsContact OD1-CD 3.29Å; D118-R121 WeakPolarHBondContact OD1-CD 3.45Å; D118-R121 IonicContact OD1-CZ 2.67Å; D118-R121 IonicContact OD1-NE 3.7Å; D118-R121 IonicContact OD1-NH1 2.61Å; D118-R121 PolarHBondContact OD1-NH1 2.86Å; A119-R121 VanDerWaalsContact C-N 3.33Å; R121-G125 WeakPolarHBondContact O-CA 3.14Å; R121-G125 PolarHBondContact O-N 3.11Å; R121-G125 VanDerWaalsContact O-N 3.12Å
122G88.2Confident90.1Very high30 Ų3063.9 Ų63.931%0.30933%0.329SS..Hα-helixtrans63-164.1177.300000113.8D58 K124 G125 A126D58-G122 PolarHBondContact OD1-N 3.33Å; G122-K124 PolarHBondContact O-N 2.83Å; G122-G125 PolarHBondContact O-N 3.21Å; G122-A126 PolarHBondContact O-N 3.12Å
123E85.1Confident90.1Very high122 Ų12256.8 Ų56.857%0.5730%0.299SS*.Hα-helixtrans-65.9-40.5-174.7-62.1-171.5155.900113.5K48 G125 A126 Q127K48-E123 IonicContact NZ-OE1 3.74Å; K48-E123 PolarHBondContact NZ-OE1 2.92Å; E123-G125 VanDerWaalsContact C-N 3.31Å; E123-A126 PolarHBondContact O-N 3.46Å; E123-Q127 WeakPolarHBondContact O-CG 3.24Å; E123-Q127 PolarHBondContact O-N 3.29Å; E123-Q127 VanDerWaalsContact O-N 3.12Å
124K87.6Confident89.9Confident180 Ų18055.1 Ų55.178%0.78329%0.294SS*.Hα-helixtrans-64.6-39.3176.6-66.9-178.5-178.9176.80110.9G122 Q127 L128G122-K124 PolarHBondContact O-N 2.83Å; K124-Q127 PolarHBondContact O-N 3.44Å; K124-L128 PolarHBondContact O-N 2.68Å
125G87.2Confident89.7Confident0 Ų056.8 Ų56.80%031%0.306CS..Hα-helixtrans-65.7-39175.500000113.3A119 L120 R121 G122 E123 Q127 L128 A129A119-G125 WeakPolarHBondContact O-CA 3.33Å; L120-G125 VanDerWaalsContact C-CA 3.43Å; R121-G125 WeakPolarHBondContact O-CA 3.14Å; R121-G125 PolarHBondContact O-N 3.11Å; R121-G125 VanDerWaalsContact O-N 3.12Å; G122-G125 PolarHBondContact O-N 3.21Å; E123-G125 VanDerWaalsContact C-N 3.31Å; G125-Q127 VanDerWaalsContact C-N 3.32Å; G125-Q127 PolarHBondContact O-N 2.98Å; G125-L128 PolarHBondContact O-N 2.92Å; G125-A129 WeakPolarHBondContact O-CB 3.33Å; G125-A129 PolarHBondContact O-N 3.48Å
126A86.8Confident89.5Confident29 Ų2953.4 Ų53.424%0.2430%0.298CS..Hα-helixtrans-62-39.217300000112.2F46 G122 E123 A129 A130F46-A126 HydrophobicContact CD1-CB 4.25Å; G122-A126 PolarHBondContact O-N 3.12Å; E123-A126 PolarHBondContact O-N 3.46Å; A126-A129 PolarHBondContact O-N 3.47Å; A126-A130 WeakPolarHBondContact O-CB 3.44Å; A126-A130 PolarHBondContact O-N 2.67Å
127Q88.9Confident89.1Confident117 Ų11755.8 Ų55.855%0.54731%0.308SS..Hα-helixtrans-66.3-42.7174.3-67.6171.714.300111.8E123 K124 G125 A130 Q131E123-Q127 WeakPolarHBondContact O-CG 3.24Å; E123-Q127 PolarHBondContact O-N 3.29Å; E123-Q127 VanDerWaalsContact O-N 3.12Å; K124-Q127 PolarHBondContact O-N 3.44Å; G125-Q127 VanDerWaalsContact C-N 3.32Å; G125-Q127 PolarHBondContact O-N 2.98Å; Q127-A130 PolarHBondContact O-N 2.9Å; Q127-Q131 WeakPolarHBondContact O-CG 3.38Å; Q127-Q131 PolarHBondContact O-N 3.04Å
128L90.6Very high88.6Confident59 Ų5956.6 Ų56.631%0.30931%0.312SS..Hα-helixtrans-62.5-42.9175.6-179.663000111.4A119 L120 K124 G125 Q131 T132A119-L128 HydrophobicContact CB-CD2 4.06Å; L120-L128 HydrophobicContact CD2-CD2 4.13Å; L120-L128 HydrophobicContact CD2-CG 4.25Å; K124-L128 PolarHBondContact O-N 2.68Å; G125-L128 PolarHBondContact O-N 2.92Å; L128-Q131 PolarHBondContact O-N 3.35Å; L128-T132 VanDerWaalsContact O-CB 3.24Å; L128-T132 WeakPolarHBondContact O-CB 3.36Å; L128-T132 PolarHBondContact O-N 3.49Å; L128-T132 PolarHBondContact O-OG1 3.35Å
129A89.8Confident88.3Confident1 Ų154.3 Ų54.31%0.00830%0.301CS..Hα-helixtrans-61.8-44.7175.200000111F46 F57 L120 G125 A126 Q131 T132 L133 G134F46-A129 HydrophobicContact CE1-CB 3.95Å; F46-A129 HydrophobicContact CZ-CB 4.21Å; F57-A129 HydrophobicContact CE1-CB 3.96Å; F57-A129 HydrophobicContact CZ-CB 3.89Å; L120-A129 HydrophobicContact CD2-CB 4.23Å; G125-A129 WeakPolarHBondContact O-CB 3.33Å; G125-A129 PolarHBondContact O-N 3.48Å; A126-A129 PolarHBondContact O-N 3.47Å; A129-Q131 VanDerWaalsContact C-N 3.33Å; A129-Q131 PolarHBondContact O-N 3.07Å; A129-T132 PolarHBondContact O-N 2.95Å; A129-L133 HydrophobicContact CB-CD1 4.19Å; A129-L133 WeakPolarHBondContact O-CA 3.28Å; A129-L133 WeakPolarHBondContact O-CB 3.45Å; A129-L133 PolarHBondContact O-N 2.96Å; A129-G134 PolarHBondContact O-N 3.16Å
130A89.1Confident88.3Confident61 Ų6152 Ų5250%0.50428%0.282SS..Hα-helixtrans-61.7-39.1176.300000112.5A126 Q127 G134A126-A130 WeakPolarHBondContact O-CB 3.44Å; A126-A130 PolarHBondContact O-N 2.67Å; Q127-A130 PolarHBondContact O-N 2.9Å; A130-G134 VanDerWaalsContact O-CA 3.3Å; A130-G134 WeakPolarHBondContact O-CA 3.43Å; A130-G134 PolarHBondContact O-N 3.34Å
131Q89.8Confident88.2Confident155 Ų15552 Ų5272%0.72428%0.282SS*.Hα-helixtrans-73.3-39.3177.5-71.1174.313.400113Q127 L128 A129Q127-Q131 WeakPolarHBondContact O-CG 3.38Å; Q127-Q131 PolarHBondContact O-N 3.04Å; L128-Q131 PolarHBondContact O-N 3.35Å; A129-Q131 VanDerWaalsContact C-N 3.33Å; A129-Q131 PolarHBondContact O-N 3.07Å
132T89.9Confident88.2Confident46 Ų4650.1 Ų50.128%0.28228%0.277SS..Hα-helixtrans-87.6-40.7-171.5-50.20000112.1Q89 L128 A129Q89-T132 WeakPolarHBondContact CG-O 3.25Å; L128-T132 VanDerWaalsContact O-CB 3.24Å; L128-T132 WeakPolarHBondContact O-CB 3.36Å; L128-T132 PolarHBondContact O-N 3.49Å; L128-T132 PolarHBondContact O-OG1 3.35Å; A129-T132 PolarHBondContact O-N 2.95Å
133L90.5Very high88.5Confident1 Ų148.7 Ų48.71%0.00526%0.263CS..THydrogen-bonded Turntrans-100.3-44.9-175.2-52.6175.3000110.9F84 T87 E88 Q89 Y101 A129F84-L133 HydrophobicContact CB-CD1 4.29Å; F84-L133 HydrophobicContact CD1-CD1 4.03Å; F84-L133 HydrophobicContact CD2-CD1 3.84Å; F84-L133 HydrophobicContact CD2-CD2 3.99Å; F84-L133 HydrophobicContact CE1-CD1 4.32Å; F84-L133 HydrophobicContact CE2-CD1 4.12Å; F84-L133 HydrophobicContact CG-CD1 3.78Å; F84-L133 HydrophobicContact CG-CD2 4.43Å; F84-L133 HydrophobicContact CZ-CD1 4.36Å; T87-L133 WeakPolarHBondContact CB-O 3.43Å; T87-L133 HydrophobicContact CG2-CB 3.8Å; T87-L133 HydrophobicContact CG2-CD2 4.37Å; T87-L133 HydrophobicContact CG2-CG 4.48Å; E88-L133 PolarHBondContact N-O 2.85Å; Q89-L133 PolarHBondContact N-O 2.62Å; Y101-L133 HydrophobicContact CD1-CD2 3.68Å; Y101-L133 HydrophobicContact CD2-CD2 3.99Å; Y101-L133 HydrophobicContact CE1-CD2 4.1Å; Y101-L133 HydrophobicContact CE2-CD2 4.37Å; Y101-L133 HydrophobicContact CG-CD2 3.64Å; A129-L133 HydrophobicContact CB-CD1 4.19Å; A129-L133 WeakPolarHBondContact O-CA 3.28Å; A129-L133 WeakPolarHBondContact O-CB 3.45Å; A129-L133 PolarHBondContact O-N 2.96Å
134G88.8Confident89Confident7 Ų742.9 Ų42.97%0.07224%0.236CC..  trans62-179.7-165.700000112.6T87 E88 A129 A130T87-G134 WeakPolarHBondContact CA-O 3.4Å; E88-G134 PolarHBondContact N-O 3.28Å; A129-G134 PolarHBondContact O-N 3.16Å; A130-G134 VanDerWaalsContact O-CA 3.3Å; A130-G134 WeakPolarHBondContact O-CA 3.43Å; A130-G134 PolarHBondContact O-N 3.34Å
135S87.8Confident89.3Confident38 Ų3839.4 Ų39.427%0.26622%0.218SC..  trans-125.3118.3175.9-620000110.4A41 G86A41-S135 PolarHBondContact O-OG 3.42Å; G86-S135 WeakPolarHBondContact O-CA 3.25Å
136G85.2Confident89.6Confident30 Ų3039.4 Ų39.431%0.30922%0.218SC..  trans-122.9-162.3-17500000113.7G86G86-G136 PolarHBondContact O-N 3.27Å
137E84.8Confident89.9Confident114 Ų11438 Ų3853%0.53321%0.207SC..  trans-69.7152.3173.8-78-168.7-163.800111.9H99 R179H99-E137 WeakPolarHBondContact CB-O 3.38Å; H99-E137 VanDerWaalsContact CG-O 3.26Å; E137-R179 IonicContact OE2-CZ 2.93Å; E137-R179 IonicContact OE2-NH1 2.59Å; E137-R179 PolarHBondContact OE2-NH1 3.09Å; E137-R179 IonicContact OE2-NH2 3.71Å; E137-R179 PolarHBondContact OE2-NH2 3.39Å
138T82.4Confident90.1Very high16 Ų1633.6 Ų33.610%0.09819%0.19CC..  trans-107.1128-175.549.10000111.9S42 G86 R169 P172 R179S42-T138 WeakPolarHBondContact OG-CG2 3.46Å; G86-T138 VanDerWaalsContact CA-CG2 3.45Å; T138-R169 VanDerWaalsContact CG2-NH1 3.31Å; T138-R169 PolarHBondContact OG1-NH1 3.37Å; T138-P172 PolarHBondContact OG1-O 3.33Å; T138-R179 PolarHBondContact O-NH1 3.41Å
139S84.9Confident90.2Very high10 Ų1032.9 Ų32.97%0.0719%0.186CC..  trans-133.492.2174.6-178.50000108.4G141 D142 A143S139-G141 VanDerWaalsContact C-N 3.26Å; S139-G141 PolarHBondContact O-N 3.42Å; S139-D142 WeakPolarHBondContact CB-OD2 3.41Å; S139-D142 PolarHBondContact O-N 3.03Å; S139-D142 WeakPolarHBondContact OG-CB 3.24Å; S139-D142 PolarHBondContact OG-OD2 3.02Å; S139-A143 PolarHBondContact O-N 3.22Å
140L91.4Very high90.3Very high1 Ų132.8 Ų32.81%0.00519%0.186CC..Hα-helixtrans-67.8-32.4179.4-174.266.7000110.9L38 Y85 D142 A143 L144 P172 H173 A183 F213 F214L38-L140 HydrophobicContact CD2-CD1 4.07Å; Y85-L140 HydrophobicContact CD2-CD1 4.5Å; Y85-L140 HydrophobicContact CE1-CD1 4.46Å; Y85-L140 HydrophobicContact CE2-CD1 4.15Å; L140-D142 PolarHBondContact O-N 2.95Å; L140-A143 PolarHBondContact O-N 2.95Å; L140-L144 HydrophobicContact CD1-CG 4.42Å; L140-L144 HydrophobicContact CD2-CD1 4.47Å; L140-L144 HydrophobicContact CG-CD1 4.09Å; L140-L144 HydrophobicContact CG-CG 4.16Å; L140-L144 WeakPolarHBondContact O-CB 3.47Å; L140-L144 VanDerWaalsContact O-CG 3.25Å; L140-L144 WeakPolarHBondContact O-CG 3.44Å; L140-L144 PolarHBondContact O-N 3Å; L140-P172 HydrophobicContact CD2-CG 4.41Å; L140-H173 WeakPolarHBondContact CB-NE2 3.42Å; L140-H173 PolarHBondContact N-NE2 2.87Å; L140-H173 VanDerWaalsContact N-NE2 3.11Å; L140-A183 HydrophobicContact CB-CB 4.35Å; L140-F213 HydrophobicContact CD2-CE1 3.51Å; L140-F213 HydrophobicContact CD2-CZ 3.98Å; L140-F214 HydrophobicContact CD2-CE1 4.04Å; L140-F214 HydrophobicContact CD2-CZ 4.31Å
141G91.8Very high90.4Very high1 Ų130.4 Ų30.41%0.0116%0.164CC..Hα-helixtrans-59.5-43.7176.900000113S139 W145S139-G141 VanDerWaalsContact C-N 3.26Å; S139-G141 PolarHBondContact O-N 3.42Å; G141-W145 WeakPolarHBondContact O-CB 3.3Å; G141-W145 PolarHBondContact O-N 3.4Å
142D92.6Very high90.3Very high34 Ų3427.4 Ų27.418%0.18216%0.16CC..Hα-helixtrans-70.6-36.3176.8-63.9-31.4000111.7F97 V100 S139 L140 W145 C146 Q182F97-D142 HydrophobicContact CB-CB 4.15Å; F97-D142 HydrophobicContact CD1-CB 3.91Å; F97-D142 HydrophobicContact CG-CB 4.24Å; V100-D142 HydrophobicContact CG2-CB 4.41Å; S139-D142 WeakPolarHBondContact CB-OD2 3.41Å; S139-D142 PolarHBondContact O-N 3.03Å; S139-D142 WeakPolarHBondContact OG-CB 3.24Å; S139-D142 PolarHBondContact OG-OD2 3.02Å; L140-D142 PolarHBondContact O-N 2.95Å; D142-W145 PolarHBondContact O-N 3.36Å; D142-C146 WeakPolarHBondContact O-CB 3.39Å; D142-C146 PolarHBondContact O-N 2.84Å; D142-Q182 PolarHBondContact OD1-NE2 3.43Å
143A94Very high90.2Very high0 Ų029.8 Ų29.80%017%0.171CC..Hα-helixtrans-64-44.3175.200000112.4L38 Y85 V100 S139 L140 W145 C146 C147L38-A143 HydrophobicContact CD1-CB 4.1Å; L38-A143 HydrophobicContact CD2-CB 4.26Å; Y85-A143 HydrophobicContact CG-CB 4.15Å; V100-A143 HydrophobicContact CG2-CB 4.02Å; S139-A143 PolarHBondContact O-N 3.22Å; L140-A143 PolarHBondContact O-N 2.95Å; A143-W145 VanDerWaalsContact C-N 3.33Å; A143-C146 WeakPolarHBondContact O-CB 3.26Å; A143-C146 PolarHBondContact O-N 3.23Å; A143-C147 PolarHBondContact O-N 3.44Å; A143-C147 PolarHBondContact O-SG 3.16Å
144L95.1Very high90.1Very high0 Ų031.5 Ų31.50%018%0.18CC..Hα-helixtrans-62-42174.5-71.5173.5000111.2L38 L140 C147 A148 L163 I165 A183 K186 A187 L190L38-L144 HydrophobicContact CD2-CD2 4.39Å; L140-L144 HydrophobicContact CD1-CG 4.42Å; L140-L144 HydrophobicContact CD2-CD1 4.47Å; L140-L144 HydrophobicContact CG-CD1 4.09Å; L140-L144 HydrophobicContact CG-CG 4.16Å; L140-L144 WeakPolarHBondContact O-CB 3.47Å; L140-L144 VanDerWaalsContact O-CG 3.25Å; L140-L144 WeakPolarHBondContact O-CG 3.44Å; L140-L144 PolarHBondContact O-N 3Å; L144-C147 WeakPolarHBondContact O-CB 3.47Å; L144-C147 PolarHBondContact O-N 2.99Å; L144-A148 PolarHBondContact O-N 2.93Å; L144-L163 HydrophobicContact CD2-CD2 3.51Å; L144-I165 HydrophobicContact CD2-CD1 4.42Å; L144-A183 WeakPolarHBondContact CD1-O 3.49Å; L144-K186 HydrophobicContact CB-CB 4.15Å; L144-A187 HydrophobicContact CD1-CB 4.04Å; L144-L190 HydrophobicContact CB-CD1 3.94Å; L144-L190 HydrophobicContact CD2-CD1 3.86Å; L144-L190 HydrophobicContact CG-CD1 4.44Å
145W93.2Very high90Very high107 Ų10741.4 Ų41.441%0.40522%0.221SC..Hα-helixtrans-65.9-41.3176.2-169.26.9000112F97 G141 D142 A143 C147 A148 N149 K186F97-W145 HydrophobicContact CD1-CE3 4.31Å; F97-W145 HydrophobicContact CE1-CB 4.46Å; F97-W145 AromaticContact CE1-CD2 3.62Å; F97-W145 HydrophobicContact CE1-CD2 3.62Å; F97-W145 AromaticContact CE1-CE3 3.2Å; F97-W145 HydrophobicContact CE1-CE3 3.2Å; F97-W145 HydrophobicContact CE1-CG 4.2Å; F97-W145 HydrophobicContact CE1-CH2 4.25Å; F97-W145 AromaticContact CE1-CZ3 3.56Å; F97-W145 HydrophobicContact CE1-CZ3 3.56Å; F97-W145 HydrophobicContact CZ-CB 4.22Å; F97-W145 AromaticContact CZ-CD2 3.44Å; F97-W145 HydrophobicContact CZ-CD2 3.44Å; F97-W145 VanDerWaalsContact CZ-CD2 3.44Å; F97-W145 AromaticContact CZ-CE2 3.85Å; F97-W145 AromaticContact CZ-CE3 3.58Å; F97-W145 HydrophobicContact CZ-CE3 3.58Å; F97-W145 AromaticContact CZ-CG 3.77Å; F97-W145 HydrophobicContact CZ-CG 3.77Å; F97-W145 HydrophobicContact CZ-CH2 4.39Å; F97-W145 HydrophobicContact CZ-CZ2 4.31Å; F97-W145 HydrophobicContact CZ-CZ3 4.06Å; G141-W145 WeakPolarHBondContact O-CB 3.3Å; G141-W145 PolarHBondContact O-N 3.4Å; D142-W145 PolarHBondContact O-N 3.36Å; A143-W145 VanDerWaalsContact C-N 3.33Å; W145-C147 VanDerWaalsContact C-N 3.29Å; W145-C147 PolarHBondContact O-N 3.1Å; W145-A148 WeakPolarHBondContact O-CB 3.37Å; W145-A148 PolarHBondContact O-N 3.46Å; W145-A148 VanDerWaalsContact O-N 3.1Å; W145-N149 PolarHBondContact NE1-OD1 3.21Å; W145-N149 PolarHBondContact O-N 3.27Å; W145-K186 HydrophobicContact CB-CD 4.11Å; W145-K186 HydrophobicContact CG-CD 4.23Å
146C94Very high90Very high1 Ų143.5 Ų43.51%0.00723%0.229CC..Hα-helixtrans-56.7-44.7172.3-172.20000111.3F97 V100 D142 A143 A148 N149 L150F97-C146 HydrophobicContact CD2-CB 3.83Å; F97-C146 HydrophobicContact CE2-CB 4.17Å; V100-C146 HydrophobicContact CG1-CB 3.87Å; D142-C146 WeakPolarHBondContact O-CB 3.39Å; D142-C146 PolarHBondContact O-N 2.84Å; A143-C146 WeakPolarHBondContact O-CB 3.26Å; A143-C146 PolarHBondContact O-N 3.23Å; C146-A148 VanDerWaalsContact C-N 3.32Å; C146-A148 PolarHBondContact O-N 3.31Å; C146-N149 PolarHBondContact O-N 3.19Å; C146-L150 WeakPolarHBondContact O-CG 3.31Å; C146-L150 PolarHBondContact O-N 2.99Å; C146-L150 VanDerWaalsContact O-N 3.14Å
147C94.2Very high90Very high0 Ų050.7 Ų50.70%025%0.246CC..Hα-helixtrans-62.8-37.1176-63.30000112.5V36 A143 L144 W145 N149 L150 Y151 L163V36-C147 HydrophobicContact CG1-CB 4.43Å; A143-C147 PolarHBondContact O-N 3.44Å; A143-C147 PolarHBondContact O-SG 3.16Å; L144-C147 WeakPolarHBondContact O-CB 3.47Å; L144-C147 PolarHBondContact O-N 2.99Å; W145-C147 VanDerWaalsContact C-N 3.29Å; W145-C147 PolarHBondContact O-N 3.1Å; C147-N149 VanDerWaalsContact C-N 3.31Å; C147-N149 PolarHBondContact O-N 3.2Å; C147-L150 WeakPolarHBondContact O-CB 3.27Å; C147-L150 PolarHBondContact O-N 3.37Å; C147-Y151 WeakPolarHBondContact O-CD2 3.48Å; C147-Y151 PolarHBondContact O-N 3.2Å; C147-L163 HydrophobicContact CB-CD1 4.07Å
148A92.4Very high90Very high23 Ų2346.6 Ų46.619%0.1923%0.228CC..Hα-helixtrans-61.7-38.8174.900000112.3L144 W145 C146 Y151 S152 L190L144-A148 PolarHBondContact O-N 2.93Å; W145-A148 WeakPolarHBondContact O-CB 3.37Å; W145-A148 PolarHBondContact O-N 3.46Å; W145-A148 VanDerWaalsContact O-N 3.1Å; C146-A148 VanDerWaalsContact C-N 3.32Å; C146-A148 PolarHBondContact O-N 3.31Å; A148-Y151 PolarHBondContact O-N 3.37Å; A148-S152 PolarHBondContact O-N 3.09Å; A148-S152 PolarHBondContact O-OG 2.89Å; A148-L190 HydrophobicContact CB-CD2 3.56Å; A148-L190 HydrophobicContact CB-CG 4.25Å
149N91.9Very high90.1Very high44 Ų4447.8 Ų47.824%0.23524%0.237CC..Hα-helixtrans-67.8-39.4177.1-64.7-12000111.3Q93 W145 C146 C147 Y151 S152 D153Q93-N149 VanDerWaalsContact OE1-CB 3.32Å; W145-N149 PolarHBondContact NE1-OD1 3.21Å; W145-N149 PolarHBondContact O-N 3.27Å; C146-N149 PolarHBondContact O-N 3.19Å; C147-N149 VanDerWaalsContact C-N 3.31Å; C147-N149 PolarHBondContact O-N 3.2Å; N149-Y151 VanDerWaalsContact C-N 3.29Å; N149-Y151 PolarHBondContact O-N 3.28Å; N149-S152 PolarHBondContact O-N 2.73Å; N149-D153 PolarHBondContact O-N 2.91Å
150L91.7Very high90.1Very high0 Ų050.7 Ų50.70%025%0.249CC..Hα-helixtrans-55.7-43.6174.3-63.2177.4000111.9V36 A81 V83 V102 D105 C146 C147 S152V36-L150 HydrophobicContact CG1-CD1 4.48Å; A81-L150 HydrophobicContact CB-CD1 4.28Å; V83-L150 HydrophobicContact CG2-CD1 3.54Å; V102-L150 HydrophobicContact CG1-CD2 4.22Å; V102-L150 HydrophobicContact CG2-CD2 4.47Å; D105-L150 VanDerWaalsContact OD1-CD2 3.26Å; D105-L150 WeakPolarHBondContact OD1-CD2 3.39Å; C146-L150 WeakPolarHBondContact O-CG 3.31Å; C146-L150 PolarHBondContact O-N 2.99Å; C146-L150 VanDerWaalsContact O-N 3.14Å; C147-L150 WeakPolarHBondContact O-CB 3.27Å; C147-L150 PolarHBondContact O-N 3.37Å; L150-S152 VanDerWaalsContact C-N 3.32Å; L150-S152 PolarHBondContact O-N 3.05Å
151Y91.3Very high90.1Very high10 Ų1053.2 Ų53.24%0.03926%0.26CS..Hα-helixtrans-67.8-31.9176.3-71.7-61.7000113.7S34 V36 L106 C147 A148 N149 L158 K161 R162 V195S34-Y151 WeakPolarHBondContact OG-CE1 2.89Å; V36-Y151 HydrophobicContact CG2-CE1 3.95Å; V36-Y151 HydrophobicContact CG2-CE2 3.96Å; V36-Y151 VanDerWaalsContact CG2-CZ 3.48Å; V36-Y151 VanDerWaalsContact CG2-OH 3.31Å; V36-Y151 WeakPolarHBondContact CG2-OH 3.19Å; L106-Y151 HydrophobicContact CD2-CD1 3.88Å; L106-Y151 HydrophobicContact CD2-CE1 4.17Å; C147-Y151 WeakPolarHBondContact O-CD2 3.48Å; C147-Y151 PolarHBondContact O-N 3.2Å; A148-Y151 PolarHBondContact O-N 3.37Å; N149-Y151 VanDerWaalsContact C-N 3.29Å; N149-Y151 PolarHBondContact O-N 3.28Å; Y151-L158 HydrophobicContact CD1-CD1 3.97Å; Y151-K161 HydrophobicContact CD1-CB 4.07Å; Y151-K161 HydrophobicContact CD1-CD 4.07Å; Y151-K161 HydrophobicContact CD1-CG 3.95Å; Y151-K161 HydrophobicContact CE1-CB 3.73Å; Y151-K161 HydrophobicContact CE1-CG 4.07Å; Y151-K161 HydrophobicContact CG-CD 4.24Å; Y151-R162 PolarHBondContact OH-N 3.16Å; Y151-R162 PolarHBondContact OH-O 3.28Å; Y151-V195 HydrophobicContact CD2-CG2 3.98Å; Y151-V195 HydrophobicContact CE2-CG1 3.89Å; Y151-V195 HydrophobicContact CE2-CG2 3.97Å
152S88.7Confident90.1Very high93 Ų9354.4 Ų54.465%0.6526%0.264SS*.Hα-helixtrans-78.8-29-175.2-58.60000112.5A148 N149 L150 I154A148-S152 PolarHBondContact O-N 3.09Å; A148-S152 PolarHBondContact O-OG 2.89Å; N149-S152 PolarHBondContact O-N 2.73Å; L150-S152 VanDerWaalsContact C-N 3.32Å; L150-S152 PolarHBondContact O-N 3.05Å; S152-I154 VanDerWaalsContact C-N 3.3Å; S152-I154 PolarHBondContact O-N 3.35Å
153D88.2Confident90.2Very high96 Ų9652.8 Ų52.851%0.51326%0.256SS..Hα-helixtrans-78.1-15.8-178.5-80.13.7000113.5Q93 N149 K155Q93-D153 PolarHBondContact NE2-OD2 3.17Å; Q93-D153 PolarHBondContact OE1-OD2 2.92Å; Q93-D153 VanDerWaalsContact OE1-OD2 3.08Å; N149-D153 PolarHBondContact O-N 2.91Å; D153-K155 PolarHBondContact O-N 3.33Å
154I88.6Confident90.2Very high37 Ų3752.8 Ų52.819%0.1926%0.256CS..  trans-72.2118177.2-63-56.2000111.1L79 L106 S152 L156 L158L79-I154 HydrophobicContact CD1-CD1 4.17Å; L79-I154 HydrophobicContact CD1-CG1 4.24Å; L79-I154 HydrophobicContact CD1-CG2 3.89Å; L106-I154 HydrophobicContact CB-CD1 4.11Å; L106-I154 HydrophobicContact CB-CG1 4.3Å; L106-I154 HydrophobicContact CD2-CD1 4.34Å; L106-I154 HydrophobicContact CD2-CG1 3.65Å; L106-I154 HydrophobicContact CG-CD1 4.25Å; L106-I154 HydrophobicContact CG-CG1 4.09Å; L106-I154 VanDerWaalsContact O-CD1 3.32Å; L106-I154 WeakPolarHBondContact O-CD1 3.48Å; S152-I154 VanDerWaalsContact C-N 3.3Å; S152-I154 PolarHBondContact O-N 3.35Å; I154-L156 HydrophobicContact CG2-CB 3.68Å; I154-L156 HydrophobicContact CG2-CG 4.27Å; I154-L156 PolarHBondContact O-N 2.64Å; I154-L158 HydrophobicContact CB-CD1 4.34Å; I154-L158 HydrophobicContact CG2-CD1 4.4Å; I154-L158 HydrophobicContact CG2-CD2 4Å; I154-L158 HydrophobicContact CG2-CG 4.21Å
155K86.6Confident90.2Very high214 Ų21452.8 Ų52.893%0.9326%0.256SS*.  trans-76.6-11.6175.3-60.2179.8-176.5174.70113.5D153D153-K155 PolarHBondContact O-N 3.33Å
156L86.4Confident90.4Very high83 Ų8347.7 Ų47.744%0.43524%0.237SC..SBendtrans-83.3148.3-180-58.8171.2000110.1L79 I154 L158L79-L156 HydrophobicContact CD1-CD1 4.38Å; I154-L156 HydrophobicContact CG2-CB 3.68Å; I154-L156 HydrophobicContact CG2-CG 4.27Å; I154-L156 PolarHBondContact O-N 2.64Å; L156-L158 PolarHBondContact O-N 2.97Å
157R85.4Confident90.3Very high180 Ų18047.6 Ų47.668%0.67924%0.236SC*.  trans-70.5115173.4-174.5175178.5-164.1-1.6109.3S30 G31 R32S30-R157 WeakPolarHBondContact O-CD 3.34Å; S30-R157 PolarHBondContact O-NE 2.85Å; S30-R157 VanDerWaalsContact O-NE 3.15Å; S30-R157 PolarHBondContact OG-NH1 2.9Å; S30-R157 PolarHBondContact OG-NH2 3.13Å; G31-R157 CarbonylContact C-O 3.48Å; G31-R157 WeakPolarHBondContact CA-O 3.5Å; R32-R157 PolarHBondContact N-O 3.26Å
158L85.8Confident90.2Very high28 Ų2847.7 Ų47.715%0.14724%0.237CC..EExtended strand (participates in β ladder)trans-87.6127.6174.5-59.9179000109.9R32 L79 Y151 I154 L156 K161R32-L158 VanDerWaalsContact O-CA 3.3Å; R32-L158 WeakPolarHBondContact O-CA 3.46Å; L79-L158 HydrophobicContact CD1-CD2 3.87Å; Y151-L158 HydrophobicContact CD1-CD1 3.97Å; I154-L158 HydrophobicContact CB-CD1 4.34Å; I154-L158 HydrophobicContact CG2-CD1 4.4Å; I154-L158 HydrophobicContact CG2-CD2 4Å; I154-L158 HydrophobicContact CG2-CG 4.21Å; L156-L158 PolarHBondContact O-N 2.97Å; L158-K161 HydrophobicContact CB-CG 4.25Å; L158-K161 HydrophobicContact CD1-CG 4.19Å
159S83.2Confident90.1Very high42 Ų4248 Ų4829%0.29423%0.233SC..EExtended strand (participates in β ladder)trans-81.1-50.117533.40000111G31 R32 D33G31-S159 PolarHBondContact O-OG 3.44Å; R32-S159 PolarHBondContact O-N 2.92Å; R32-S159 PolarHBondContact O-OG 3.11Å; R32-S159 VanDerWaalsContact O-OG 3.1Å; D33-S159 PolarHBondContact N-OG 3.22Å; D33-S159 WeakPolarHBondContact OD1-CB 3.41Å; D33-S159 PolarHBondContact OD1-OG 2.83Å
160H85.1Confident90Very high70 Ų7046.8 Ų46.832%0.32423%0.226SC..EExtended strand (participates in β ladder)trans-131.3137.8-179.5-61.9-51.7000110.3D33 S34 K250D33-H160 WeakPolarHBondContact OD1-CB 3.14Å; D33-H160 IonicContact OD1-CD2 3.9Å; D33-H160 PolarHBondContact OD1-CD2 2.85Å; D33-H160 IonicContact OD1-CG 3.06Å; D33-H160 IonicContact OD2-CD2 3.95Å; S34-H160 PolarHBondContact N-O 3.46Å; S34-H160 PolarHBondContact OG-O 2.8Å; H160-K250 VanDerWaalsContact CE1-CD 3.42Å; H160-K250 WeakPolarHBondContact CE1-CD 3.48Å
161K91.3Very high89.9Confident55 Ų5549.6 Ų49.624%0.23924%0.242CC..EExtended strand (participates in β ladder)trans-119.9119.6177.9-56.5176.5-174.3172.70108.5S34 Y151 L158 V195 L196S34-K161 WeakPolarHBondContact OG-CA 3.23Å; Y151-K161 HydrophobicContact CD1-CB 4.07Å; Y151-K161 HydrophobicContact CD1-CD 4.07Å; Y151-K161 HydrophobicContact CD1-CG 3.95Å; Y151-K161 HydrophobicContact CE1-CB 3.73Å; Y151-K161 HydrophobicContact CE1-CG 4.07Å; Y151-K161 HydrophobicContact CG-CD 4.24Å; L158-K161 HydrophobicContact CB-CG 4.25Å; L158-K161 HydrophobicContact CD1-CG 4.19Å; K161-V195 HydrophobicContact CB-CB 4.34Å; K161-V195 HydrophobicContact CB-CG1 4.47Å; K161-V195 HydrophobicContact CB-CG2 3.81Å; K161-V195 HydrophobicContact CD-CG2 3.89Å; K161-V195 WeakPolarHBondContact O-CA 3.32Å; K161-L196 PolarHBondContact O-N 2.88Å
162R92.1Very high89.7Confident25 Ų2549.2 Ų49.29%0.09424%0.24CC..EExtended strand (participates in β ladder)trans-133.4128.4-177.2-173.3175.7-67.3-115.610.4111.5S34 L35 V36 Y151 M164 L196 D198 R247S34-R162 PolarHBondContact O-N 2.84Å; L35-R162 WeakPolarHBondContact CA-O 3.5Å; L35-R162 HydrophobicContact CD1-CB 4.05Å; L35-R162 HydrophobicContact CD1-CG 4.02Å; V36-R162 PolarHBondContact N-O 2.91Å; Y151-R162 PolarHBondContact OH-N 3.16Å; Y151-R162 PolarHBondContact OH-O 3.28Å; R162-M164 HydrophobicContact CG-CG 4.44Å; R162-L196 CarbonylContact C-O 3.52Å; R162-L196 WeakPolarHBondContact CA-O 3.46Å; R162-D198 WeakPolarHBondContact CD-OD2 2.88Å; R162-D198 WeakPolarHBondContact CG-OD2 3.48Å; R162-D198 IonicContact CZ-OD2 3.6Å; R162-D198 IonicContact NE-OD2 3.29Å; R162-D198 IonicContact NH1-OD1 3.92Å; R162-D198 IonicContact NH1-OD2 2.72Å; R162-D198 PolarHBondContact NH1-OD2 3.16Å; R162-R247 WeakPolarHBondContact CD-O 3.39Å; R162-R247 PolarHBondContact NE-O 2.9Å; R162-R247 PolarHBondContact NH1-O 3.45Å; R162-R247 VanDerWaalsContact NH1-O 3.08Å
163L94.9Very high89.6Confident0 Ų045.8 Ų45.80%021%0.214CC..EExtended strand (participates in β ladder)trans-110.5119.5175.3178.968.5000108.7V36 L38 L144 C147 I165 L190 V195 L196 I197 D198V36-L163 HydrophobicContact CB-CD1 3.73Å; V36-L163 HydrophobicContact CG1-CD1 3.59Å; L38-L163 HydrophobicContact CB-CD1 3.86Å; L38-L163 HydrophobicContact CD2-CD1 4.48Å; L144-L163 HydrophobicContact CD2-CD2 3.51Å; C147-L163 HydrophobicContact CB-CD1 4.07Å; L163-I165 HydrophobicContact CD2-CG1 4.47Å; L163-I165 HydrophobicContact CG-CG1 4.38Å; L163-L190 HydrophobicContact CD2-CD1 4.26Å; L163-V195 HydrophobicContact CB-CG1 4.03Å; L163-L196 PolarHBondContact N-O 3.3Å; L163-I197 HydrophobicContact CB-CG1 4.43Å; L163-I197 HydrophobicContact CD2-CG1 4.29Å; L163-I197 HydrophobicContact CD2-CG2 4.36Å; L163-I197 CarbonylContact O-C 3.54Å; L163-I197 WeakPolarHBondContact O-CA 3.36Å; L163-D198 PolarHBondContact O-N 3.37Å
164M95Very high89.4Confident0 Ų044.3 Ų44.30%022%0.221CC..EExtended strand (participates in β ladder)trans-106.1119.6174.4-68.1-175.317900109.9L35 V36 F37 L38 R162 F166 D198 V244 R247L35-M164 HydrophobicContact CD1-CE 3.92Å; L35-M164 HydrophobicContact CD1-CG 3.84Å; L35-M164 HydrophobicContact CD1-SD 3.92Å; V36-M164 PolarHBondContact O-N 3.46Å; F37-M164 HydrophobicContact CE1-SD 4.31Å; L38-M164 PolarHBondContact N-O 3.29Å; R162-M164 HydrophobicContact CG-CG 4.44Å; M164-F166 HydrophobicContact CB-CD2 4.4Å; M164-F166 HydrophobicContact CB-CE2 3.59Å; M164-F166 HydrophobicContact CB-CZ 4.29Å; M164-D198 WeakPolarHBondContact CA-O 3.12Å; M164-D198 HydrophobicContact CG-CB 4.23Å; M164-V244 HydrophobicContact CE-CG1 4.5Å; M164-V244 HydrophobicContact SD-CG1 4.06Å; M164-R247 VanDerWaalsContact CE-C 3.48Å; M164-R247 HydrophobicContact CE-CB 3.7Å; M164-R247 WeakPolarHBondContact CE-O 3.49Å
165I95.3Very high88.9Confident0 Ų045.1 Ų45.10%024%0.239CC..EExtended strand (participates in β ladder)trans-97123.4-179.8-53.9179.8000109.2L38 L144 L163 T167 I197 D198 L199 M200 F214 I217L38-I165 HydrophobicContact CD2-CG1 4.27Å; L38-I165 CarbonylContact O-C 3.59Å; L38-I165 WeakPolarHBondContact O-CA 3.35Å; L144-I165 HydrophobicContact CD2-CD1 4.42Å; L163-I165 HydrophobicContact CD2-CG1 4.47Å; L163-I165 HydrophobicContact CG-CG1 4.38Å; I165-T167 HydrophobicContact CG2-CG2 4.25Å; I165-I197 HydrophobicContact CD1-CG2 3.7Å; I165-I197 HydrophobicContact CG1-CG2 4.21Å; I165-D198 PolarHBondContact N-O 3.01Å; I165-L199 HydrophobicContact CB-CD1 4.21Å; I165-L199 HydrophobicContact CG2-CD1 4.21Å; I165-M200 WeakPolarHBondContact O-CA 3.44Å; I165-M200 WeakPolarHBondContact O-CB 3.23Å; I165-M200 PolarHBondContact O-N 3.39Å; I165-F214 HydrophobicContact CD1-CE1 4.4Å; I165-F214 HydrophobicContact CG2-CE1 4.3Å; I165-I217 HydrophobicContact CD1-CG2 4.21Å
166F95.4Very high89Confident0 Ų037.7 Ų37.70%021%0.209CC..EExtended strand (participates in β ladder)trans-111.3114.9176.4-64.8-103.6000109.5F37 L38 V39 D40 T60 M164 M200 L240 V244F37-F166 AromaticContact CD1-CE2 3.66Å; F37-F166 HydrophobicContact CD1-CE2 3.66Å; F37-F166 HydrophobicContact CD1-CZ 4.06Å; F37-F166 HydrophobicContact CE1-CE2 4.35Å; F37-F166 HydrophobicContact CE1-CZ 4.35Å; L38-F166 PolarHBondContact O-N 3.31Å; V39-F166 HydrophobicContact CG2-CB 4.32Å; V39-F166 HydrophobicContact CG2-CD2 4.25Å; V39-F166 HydrophobicContact CG2-CG 4.5Å; D40-F166 WeakPolarHBondContact CB-O 3.39Å; D40-F166 PolarHBondContact N-O 2.84Å; T60-F166 HydrophobicContact CG2-CB 3.74Å; T60-F166 HydrophobicContact CG2-CD1 3.52Å; T60-F166 HydrophobicContact CG2-CD2 4.27Å; T60-F166 HydrophobicContact CG2-CE1 4.16Å; T60-F166 HydrophobicContact CG2-CG 3.57Å; M164-F166 HydrophobicContact CB-CD2 4.4Å; M164-F166 HydrophobicContact CB-CE2 3.59Å; M164-F166 HydrophobicContact CB-CZ 4.29Å; F166-M200 HydrophobicContact CD1-CB 3.54Å; F166-M200 HydrophobicContact CD1-CG 4.06Å; F166-M200 HydrophobicContact CD2-CB 4.43Å; F166-M200 HydrophobicContact CE1-CB 3.65Å; F166-M200 HydrophobicContact CE1-CG 3.65Å; F166-M200 HydrophobicContact CE2-CB 4.47Å; F166-M200 HydrophobicContact CE2-CG 4.11Å; F166-M200 HydrophobicContact CG-CB 3.97Å; F166-M200 HydrophobicContact CG-CG 4.48Å; F166-M200 HydrophobicContact CZ-CB 4.13Å; F166-M200 HydrophobicContact CZ-CG 3.68Å; F166-L240 HydrophobicContact CD1-CD1 4.37Å; F166-L240 HydrophobicContact CE1-CD1 4.09Å; F166-V244 HydrophobicContact CE1-CG2 3.81Å; F166-V244 HydrophobicContact CZ-CG2 3.72Å
167T93.9Very high89Confident0 Ų037.8 Ų37.80%022%0.217CC..EExtended strand (participates in β ladder)trans-157.6151.4-178.8-175.90000111.7D40 Y85 I165 R169 L199 M200 H201 L202 F208 F214D40-T167 PolarHBondContact OD2-OG1 3.37Å; Y85-T167 WeakPolarHBondContact OH-CB 3.19Å; Y85-T167 PolarHBondContact OH-OG1 3.41Å; I165-T167 HydrophobicContact CG2-CG2 4.25Å; T167-R169 PolarHBondContact OG1-N 2.97Å; T167-L199 HydrophobicContact CG2-CD1 3.97Å; T167-M200 PolarHBondContact N-O 3.19Å; T167-H201 WeakPolarHBondContact O-CA 3.47Å; T167-L202 PolarHBondContact O-N 2.98Å; T167-F208 HydrophobicContact CG2-CE2 4.27Å; T167-F208 HydrophobicContact CG2-CZ 4.39Å; T167-F214 HydrophobicContact CG2-CE2 4.24Å; T167-F214 HydrophobicContact CG2-CZ 3.84Å
168C91.8Very high89.3Confident2 Ų234 Ų341%0.01421%0.214CC..SBendtrans-101.42167.764.50000113.1M45 N56 L202 K204M45-C168 HydrophobicContact SD-CB 4.03Å; M45-C168 PolarHBondContact SD-N 3.1Å; M45-C168 VanDerWaalsContact SD-SG 3.61Å; N56-C168 WeakPolarHBondContact ND2-CB 3.4Å; C168-L202 HydrophobicContact CB-CB 4.16Å; C168-K204 HydrophobicContact CB-CB 4.39Å; C168-K204 WeakPolarHBondContact O-CD 3.48Å
169R90.2Very high89.5Confident28 Ų2836.3 Ų36.311%0.10622%0.221CC..  trans-101.8119.6179.4-73.6-176-59.8148.410.7111.5D40 S42 E44 T138 T167 F208 F214D40-R169 VanDerWaalsContact CG-NH2 3.27Å; D40-R169 IonicContact OD1-CZ 3.94Å; D40-R169 IonicContact OD1-NE 2.66Å; D40-R169 IonicContact OD1-NH2 3.52Å; D40-R169 PolarHBondContact OD1-NH2 3.25Å; D40-R169 IonicContact OD2-CZ 2.8Å; D40-R169 IonicContact OD2-NE 3.69Å; D40-R169 PolarHBondContact OD2-NE 3.35Å; D40-R169 IonicContact OD2-NH2 2.71Å; D40-R169 PolarHBondContact OD2-NH2 2.98Å; S42-R169 PolarHBondContact OG-NE 3.49Å; S42-R169 PolarHBondContact OG-NH2 3.31Å; E44-R169 VanDerWaalsContact OE2-CD 3.23Å; E44-R169 WeakPolarHBondContact OE2-CD 3.41Å; E44-R169 WeakPolarHBondContact OE2-CG 3.46Å; T138-R169 VanDerWaalsContact CG2-NH1 3.31Å; T138-R169 PolarHBondContact OG1-NH1 3.37Å; T167-R169 PolarHBondContact OG1-N 2.97Å; R169-F208 VanDerWaalsContact C-CE2 3.43Å; R169-F208 WeakPolarHBondContact O-CE2 3.35Å; R169-F214 VanDerWaalsContact O-CE2 3.24Å; R169-F214 WeakPolarHBondContact O-CE2 3.04Å
170D89.4Confident89.8Confident19 Ų1935.6 Ų35.610%0.10221%0.214CC..SBendtrans-82.8-30.1176.149.33.5000113P172 K204 F208 D209 L212 F213D170-P172 WeakPolarHBondContact O-CD 3.5Å; D170-K204 IonicContact OD1-NZ 2.69Å; D170-K204 PolarHBondContact OD1-NZ 3.11Å; D170-K204 VanDerWaalsContact OD2-CE 3.24Å; D170-K204 WeakPolarHBondContact OD2-CE 3.36Å; D170-K204 IonicContact OD2-NZ 3.18Å; D170-K204 PolarHBondContact OD2-NZ 2.97Å; D170-F208 HydrophobicContact CB-CD1 4.15Å; D170-F208 HydrophobicContact CB-CD2 4.18Å; D170-F208 HydrophobicContact CB-CE1 4.05Å; D170-F208 HydrophobicContact CB-CE2 4.11Å; D170-F208 HydrophobicContact CB-CG 4.2Å; D170-F208 HydrophobicContact CB-CZ 4.03Å; D170-D209 WeakPolarHBondContact CB-O 3.48Å; D170-D209 PolarHBondContact OD2-N 2.84Å; D170-L212 HydrophobicContact CB-CD1 4.39Å; D170-F213 WeakPolarHBondContact O-CB 3.32Å
171D88.6Confident90.1Very high60 Ų6041.2 Ų41.232%0.32123%0.232SC..SBendtrans-113.988.3168.6-179.47000110.8H173 G174 G175D171-H173 VanDerWaalsContact C-N 3.27Å; D171-H173 PolarHBondContact O-N 3.08Å; D171-H173 PolarHBondContact OD1-N 3.37Å; D171-G174 PolarHBondContact OD1-N 3.36Å; D171-G174 WeakPolarHBondContact OD2-CA 3.33Å; D171-G175 PolarHBondContact OD1-N 3Å; D171-G175 PolarHBondContact OD2-N 3.18Å; D171-G175 VanDerWaalsContact OD2-N 3.12Å
172P87.1Confident90.1Very high2 Ų242 Ų421%0.01324%0.236CC..THydrogen-bonded Turntrans-72-13.5-173.426.9-33.4000114.7T138 L140 D170 F213 F214T138-P172 PolarHBondContact OG1-O 3.33Å; L140-P172 HydrophobicContact CD2-CG 4.41Å; D170-P172 WeakPolarHBondContact O-CD 3.5Å; P172-F213 HydrophobicContact CG-CD1 3.67Å; P172-F213 HydrophobicContact CG-CE1 3.6Å; P172-F213 HydrophobicContact CG-CG 4.24Å; P172-F213 HydrophobicContact CG-CZ 4.12Å; P172-F214 HydrophobicContact CG-CE2 4.38Å; P172-F214 HydrophobicContact CG-CZ 4.31Å
173H88.3Confident90.2Very high20 Ų2040.8 Ų40.89%0.09323%0.232CC..THydrogen-bonded Turntrans-117.22.8-177.4-48.9118.6000113.7L140 D171 G175 D176 R179 D180 F213L140-H173 WeakPolarHBondContact CB-NE2 3.42Å; L140-H173 PolarHBondContact N-NE2 2.87Å; L140-H173 VanDerWaalsContact N-NE2 3.11Å; D171-H173 VanDerWaalsContact C-N 3.27Å; D171-H173 PolarHBondContact O-N 3.08Å; D171-H173 PolarHBondContact OD1-N 3.37Å; H173-G175 VanDerWaalsContact C-N 3.28Å; H173-G175 PolarHBondContact O-N 2.93Å; H173-D176 HydrophobicContact CB-CB 4.25Å; H173-D176 PolarHBondContact O-N 3.22Å; H173-R179 HydrophobicContact CB-CB 4.08Å; H173-D180 IonicContact CE1-OD1 3.87Å; H173-D180 IonicContact CG-OD1 3.01Å; H173-D180 IonicContact ND1-OD1 3.8Å; H173-D180 PolarHBondContact ND1-OD1 3.13Å; H173-F213 AromaticContact CE1-CZ 3.81Å; H173-F213 AromaticContact ND1-CE2 3.99Å
174G82.4Confident90.2Very high65 Ų6544.3 Ų44.367%0.6725%0.245SC*.THydrogen-bonded Turntrans60.236.1174.300000113.2D171D171-G174 PolarHBondContact OD1-N 3.36Å; D171-G174 WeakPolarHBondContact OD2-CA 3.33Å
175G78.5Confident90.1Very high54 Ų5447.6 Ų47.656%0.55727%0.265SS*.THydrogen-bonded Turntrans84.78.2-178.800000116.6D171 H173 S177D171-G175 PolarHBondContact OD1-N 3Å; D171-G175 PolarHBondContact OD2-N 3.18Å; D171-G175 VanDerWaalsContact OD2-N 3.12Å; H173-G175 VanDerWaalsContact C-N 3.28Å; H173-G175 PolarHBondContact O-N 2.93Å; G175-S177 PolarHBondContact O-N 3.49Å
176D88.8Confident90.1Very high58 Ų5850.1 Ų50.131%0.3128%0.276SS..  trans-70.892.5170.6-174.6-13.5000111.4H173 T178 R179 D180H173-D176 HydrophobicContact CB-CB 4.25Å; H173-D176 PolarHBondContact O-N 3.22Å; D176-T178 PolarHBondContact O-N 3.04Å; D176-T178 WeakPolarHBondContact OD1-CB 3.33Å; D176-T178 PolarHBondContact OD1-N 3.35Å; D176-R179 HydrophobicContact CB-CB 4.25Å; D176-R179 HydrophobicContact CB-CG 4.41Å; D176-R179 PolarHBondContact O-N 3.19Å; D176-R179 VanDerWaalsContact O-N 3.16Å; D176-R179 PolarHBondContact OD1-N 3.4Å; D176-R179 WeakPolarHBondContact OD2-CD 3.43Å; D176-R179 VanDerWaalsContact OD2-CG 3.32Å; D176-R179 WeakPolarHBondContact OD2-CG 3.44Å; D176-R179 IonicContact OD2-NE 2.86Å; D176-R179 PolarHBondContact OD2-NE 3.11Å; D176-D180 PolarHBondContact O-N 2.93Å
177S87.4Confident90Very high86 Ų8650.1 Ų50.160%0.60128%0.276SS*.Hα-helixtrans-53.3-26.9179.265.10000114.8G175 R181G175-S177 PolarHBondContact O-N 3.49Å; S177-R181 WeakPolarHBondContact O-CB 3.36Å; S177-R181 PolarHBondContact O-N 3.28Å
178T90.7Very high90Very high99 Ų9952.5 Ų52.561%0.60729%0.293SS*.Hα-helixtrans-76.2-48.1-179.4-53.50000110.3D176 D180 R181 Q182D176-T178 PolarHBondContact O-N 3.04Å; D176-T178 WeakPolarHBondContact OD1-CB 3.33Å; D176-T178 PolarHBondContact OD1-N 3.35Å; T178-D180 VanDerWaalsContact C-N 3.31Å; T178-D180 PolarHBondContact O-N 3.4Å; T178-R181 PolarHBondContact O-N 3.5Å; T178-Q182 PolarHBondContact O-N 3.49Å
179R89.3Confident90.1Very high78 Ų7855.2 Ų55.229%0.29431%0.307SS..Hα-helixtrans-64.3-38.1175.7-71.1-178.2-175.3-166.64.7111.2E137 T138 H173 D176 Q182 A183E137-R179 IonicContact OE2-CZ 2.93Å; E137-R179 IonicContact OE2-NH1 2.59Å; E137-R179 PolarHBondContact OE2-NH1 3.09Å; E137-R179 IonicContact OE2-NH2 3.71Å; E137-R179 PolarHBondContact OE2-NH2 3.39Å; T138-R179 PolarHBondContact O-NH1 3.41Å; H173-R179 HydrophobicContact CB-CB 4.08Å; D176-R179 HydrophobicContact CB-CB 4.25Å; D176-R179 HydrophobicContact CB-CG 4.41Å; D176-R179 PolarHBondContact O-N 3.19Å; D176-R179 VanDerWaalsContact O-N 3.16Å; D176-R179 PolarHBondContact OD1-N 3.4Å; D176-R179 WeakPolarHBondContact OD2-CD 3.43Å; D176-R179 VanDerWaalsContact OD2-CG 3.32Å; D176-R179 WeakPolarHBondContact OD2-CG 3.44Å; D176-R179 IonicContact OD2-NE 2.86Å; D176-R179 PolarHBondContact OD2-NE 3.11Å; R179-Q182 PolarHBondContact O-N 3.42Å; R179-A183 WeakPolarHBondContact O-CB 3.38Å; R179-A183 PolarHBondContact O-N 3.37Å
180D90.4Very high90.2Very high26 Ų2654.1 Ų54.114%0.13930%0.303CS..Hα-helixtrans-60-49.2174.2-82.5-14.6000112.4H173 D176 T178 Q182 A183 R184 F213H173-D180 IonicContact CE1-OD1 3.87Å; H173-D180 IonicContact CG-OD1 3.01Å; H173-D180 IonicContact ND1-OD1 3.8Å; H173-D180 PolarHBondContact ND1-OD1 3.13Å; D176-D180 PolarHBondContact O-N 2.93Å; T178-D180 VanDerWaalsContact C-N 3.31Å; T178-D180 PolarHBondContact O-N 3.4Å; D180-Q182 VanDerWaalsContact C-N 3.32Å; D180-Q182 PolarHBondContact O-N 3.38Å; D180-A183 PolarHBondContact O-N 3.35Å; D180-R184 WeakPolarHBondContact O-CB 3.49Å; D180-R184 WeakPolarHBondContact O-CD 3.26Å; D180-R184 VanDerWaalsContact O-CG 3.24Å; D180-R184 WeakPolarHBondContact O-CG 3.41Å; D180-R184 PolarHBondContact O-N 3.03Å; D180-F213 HydrophobicContact CB-CD2 4.45Å; D180-F213 HydrophobicContact CB-CE2 4.06Å; D180-F213 WeakPolarHBondContact OD1-CD2 3.26Å; D180-F213 WeakPolarHBondContact OD1-CE2 3.25Å
181R91.3Very high90.3Very high189 Ų18956 Ų5671%0.71331%0.311SS*.Hα-helixtrans-61.1-43.6178.5-175.5178.1177-178.6-0.3111S177 T178 R184 T185S177-R181 WeakPolarHBondContact O-CB 3.36Å; S177-R181 PolarHBondContact O-N 3.28Å; T178-R181 PolarHBondContact O-N 3.5Å; R181-R184 PolarHBondContact O-N 2.85Å; R181-T185 PolarHBondContact O-N 3.45Å; R181-T185 PolarHBondContact O-OG1 2.96Å; R181-T185 VanDerWaalsContact O-OG1 3.1Å
182Q92.2Very high90.4Very high71 Ų7160.4 Ų60.433%0.33233%0.33SS..Hα-helixtrans-60.8-45.3177.4-175-177.6-6.900111.7D142 T178 R179 D180 T185 K186D142-Q182 PolarHBondContact OD1-NE2 3.43Å; T178-Q182 PolarHBondContact O-N 3.49Å; R179-Q182 PolarHBondContact O-N 3.42Å; D180-Q182 VanDerWaalsContact C-N 3.32Å; D180-Q182 PolarHBondContact O-N 3.38Å; Q182-T185 PolarHBondContact O-N 2.93Å; Q182-K186 WeakPolarHBondContact O-CG 3.24Å; Q182-K186 PolarHBondContact O-N 2.93Å
183A93.8Very high90.6Very high0 Ų064.2 Ų64.20%035%0.353CS..Hα-helixtrans-64-42.2177.900000112.4L140 L144 R179 D180 K186 A187 F213L140-A183 HydrophobicContact CB-CB 4.35Å; L144-A183 WeakPolarHBondContact CD1-O 3.49Å; R179-A183 WeakPolarHBondContact O-CB 3.38Å; R179-A183 PolarHBondContact O-N 3.37Å; D180-A183 PolarHBondContact O-N 3.35Å; A183-K186 PolarHBondContact O-N 2.75Å; A183-A187 WeakPolarHBondContact O-CB 3.43Å; A183-A187 PolarHBondContact O-N 2.83Å; A183-F213 HydrophobicContact CB-CE2 4.41Å; A183-F213 HydrophobicContact CB-CZ 3.78Å
184R93.6Very high90.5Very high74 Ų7465.7 Ų65.728%0.27937%0.374SS..Hα-helixtrans-61.8-45.2175.5-69.9162.4-176.5-93.81112D180 R181 A187 S188 L212 F213 D216 I217D180-R184 WeakPolarHBondContact O-CB 3.49Å; D180-R184 WeakPolarHBondContact O-CD 3.26Å; D180-R184 VanDerWaalsContact O-CG 3.24Å; D180-R184 WeakPolarHBondContact O-CG 3.41Å; D180-R184 PolarHBondContact O-N 3.03Å; R181-R184 PolarHBondContact O-N 2.85Å; R184-A187 PolarHBondContact O-N 2.93Å; R184-S188 PolarHBondContact O-N 2.94Å; R184-L212 PolarHBondContact NH2-O 3.36Å; R184-F213 HydrophobicContact CG-CE2 4.42Å; R184-D216 IonicContact CZ-OD2 3.96Å; R184-D216 VanDerWaalsContact NH1-CG 3.32Å; R184-D216 IonicContact NH1-OD2 3.45Å; R184-D216 PolarHBondContact NH1-OD2 3.25Å; R184-I217 HydrophobicContact CB-CD1 4.42Å; R184-I217 HydrophobicContact CG-CD1 3.96Å
185T94.5Very high90.9Very high69 Ų6962.7 Ų62.742%0.42334%0.342SS..Hα-helixtrans-60.7-46.7174.8-60.70000111R181 Q182 A187 S188 D189R181-T185 PolarHBondContact O-N 3.45Å; R181-T185 PolarHBondContact O-OG1 2.96Å; R181-T185 VanDerWaalsContact O-OG1 3.1Å; Q182-T185 PolarHBondContact O-N 2.93Å; T185-A187 PolarHBondContact O-N 3.48Å; T185-S188 WeakPolarHBondContact O-CB 3.43Å; T185-S188 PolarHBondContact O-N 3.38Å; T185-S188 VanDerWaalsContact O-N 3.12Å; T185-D189 VanDerWaalsContact O-CG 3.3Å; T185-D189 PolarHBondContact O-N 3.06Å
186K93.9Very high91.5Very high53 Ų5362 Ų6223%0.2333%0.325CS..Hα-helixtrans-67.3-34-179.9-70.7-69.8157.5-1440113.7L144 W145 Q182 A183 S188 D189 L190L144-K186 HydrophobicContact CB-CB 4.15Å; W145-K186 HydrophobicContact CB-CD 4.11Å; W145-K186 HydrophobicContact CG-CD 4.23Å; Q182-K186 WeakPolarHBondContact O-CG 3.24Å; Q182-K186 PolarHBondContact O-N 2.93Å; A183-K186 PolarHBondContact O-N 2.75Å; K186-S188 VanDerWaalsContact C-N 3.34Å; K186-D189 IonicContact NZ-OD2 2.59Å; K186-D189 PolarHBondContact NZ-OD2 2.95Å; K186-D189 PolarHBondContact O-N 2.84Å; K186-L190 WeakPolarHBondContact O-CG 3.46Å; K186-L190 PolarHBondContact O-N 3.41Å
187A94.2Very high91.7Very high0 Ų059.2 Ų59.20%031%0.311CS..Hα-helixtrans-64.6-39.9171.200000111.6L144 A183 R184 T185 L190 K191 I197 I217L144-A187 HydrophobicContact CD1-CB 4.04Å; A183-A187 WeakPolarHBondContact O-CB 3.43Å; A183-A187 PolarHBondContact O-N 2.83Å; R184-A187 PolarHBondContact O-N 2.93Å; T185-A187 PolarHBondContact O-N 3.48Å; A187-L190 PolarHBondContact O-N 3.42Å; A187-K191 WeakPolarHBondContact O-CE 3.32Å; A187-K191 WeakPolarHBondContact O-CG 3.47Å; A187-K191 PolarHBondContact O-N 3.16Å; A187-I197 HydrophobicContact CB-CD1 4.07Å; A187-I217 HydrophobicContact CB-CB 4.33Å; A187-I217 HydrophobicContact CB-CD1 3.64Å; A187-I217 HydrophobicContact CB-CG2 3.94Å
188S93.6Very high91.8Very high50 Ų5055.4 Ų55.435%0.3528%0.284SS..Hα-helixtrans-62.1-48.9173.8-161.80000111.5R184 T185 K186 L190 K191 E192R184-S188 PolarHBondContact O-N 2.94Å; T185-S188 WeakPolarHBondContact O-CB 3.43Å; T185-S188 PolarHBondContact O-N 3.38Å; T185-S188 VanDerWaalsContact O-N 3.12Å; K186-S188 VanDerWaalsContact C-N 3.34Å; S188-L190 VanDerWaalsContact C-N 3.29Å; S188-L190 PolarHBondContact O-N 3Å; S188-K191 PolarHBondContact O-N 3.05Å; S188-K191 VanDerWaalsContact O-N 3.09Å; S188-E192 WeakPolarHBondContact O-CG 3.48Å; S188-E192 PolarHBondContact O-N 2.87Å
189D93.3Very high91.8Very high59 Ų5951.4 Ų51.432%0.31626%0.258SS..Hα-helixtrans-54.3-46.5177-63.5-11000110.7T185 K186 E192 T193T185-D189 VanDerWaalsContact O-CG 3.3Å; T185-D189 PolarHBondContact O-N 3.06Å; K186-D189 IonicContact NZ-OD2 2.59Å; K186-D189 PolarHBondContact NZ-OD2 2.95Å; K186-D189 PolarHBondContact O-N 2.84Å; D189-E192 PolarHBondContact O-N 3.31Å; D189-T193 WeakPolarHBondContact O-CG2 3.36Å; D189-T193 PolarHBondContact O-N 3.3Å; D189-T193 VanDerWaalsContact O-N 3.16Å
190L93Very high91.9Very high4 Ų447.7 Ų47.72%0.02124%0.244CC..Hα-helixtrans-60.4-46.4176.7-83.1169.8000112.3L144 A148 L163 K186 A187 S188 E192 T193 G194 V195 I197L144-L190 HydrophobicContact CB-CD1 3.94Å; L144-L190 HydrophobicContact CD2-CD1 3.86Å; L144-L190 HydrophobicContact CG-CD1 4.44Å; A148-L190 HydrophobicContact CB-CD2 3.56Å; A148-L190 HydrophobicContact CB-CG 4.25Å; L163-L190 HydrophobicContact CD2-CD1 4.26Å; K186-L190 WeakPolarHBondContact O-CG 3.46Å; K186-L190 PolarHBondContact O-N 3.41Å; A187-L190 PolarHBondContact O-N 3.42Å; S188-L190 VanDerWaalsContact C-N 3.29Å; S188-L190 PolarHBondContact O-N 3Å; L190-E192 VanDerWaalsContact C-N 3.32Å; L190-E192 PolarHBondContact O-N 3.44Å; L190-T193 PolarHBondContact O-N 2.92Å; L190-T193 VanDerWaalsContact O-N 3.11Å; L190-T193 PolarHBondContact O-OG1 3.25Å; L190-G194 PolarHBondContact O-N 3.39Å; L190-V195 HydrophobicContact CB-CB 4.31Å; L190-V195 HydrophobicContact CD2-CB 4.36Å; L190-V195 HydrophobicContact CD2-CG2 3.98Å; L190-V195 WeakPolarHBondContact O-CB 3.21Å; L190-V195 PolarHBondContact O-N 3.1Å; L190-V195 VanDerWaalsContact O-N 3.14Å; L190-I197 HydrophobicContact CB-CD1 4.12Å; L190-I197 HydrophobicContact CD1-CD1 4.21Å
191K92.3Very high91.8Very high58 Ų5846.6 Ų46.625%0.25224%0.238SC..Hα-helixtrans-61.3-40.6178.4-74.3-177.2-70.3-163.40111.7A187 S188 T193 G194 I197 D216 I217 V218A187-K191 WeakPolarHBondContact O-CE 3.32Å; A187-K191 WeakPolarHBondContact O-CG 3.47Å; A187-K191 PolarHBondContact O-N 3.16Å; S188-K191 PolarHBondContact O-N 3.05Å; S188-K191 VanDerWaalsContact O-N 3.09Å; K191-T193 VanDerWaalsContact C-N 3.26Å; K191-T193 PolarHBondContact O-N 2.96Å; K191-G194 PolarHBondContact O-N 3.27Å; K191-I197 HydrophobicContact CG-CD1 4.2Å; K191-I197 HydrophobicContact CG-CG1 4.5Å; K191-D216 PolarHBondContact NZ-O 3.27Å; K191-I217 PolarHBondContact NZ-O 3.08Å; K191-I217 VanDerWaalsContact NZ-O 3.13Å; K191-V218 PolarHBondContact NZ-O 3.19Å
192E90.9Very high91.7Very high154 Ų15437.6 Ų37.672%0.7220%0.204SC*.Hα-helixtrans-62.9-31.3175.4-72176.1-162.100112.7S188 D189 L190 G194S188-E192 WeakPolarHBondContact O-CG 3.48Å; S188-E192 PolarHBondContact O-N 2.87Å; D189-E192 PolarHBondContact O-N 3.31Å; L190-E192 VanDerWaalsContact C-N 3.32Å; L190-E192 PolarHBondContact O-N 3.44Å; E192-G194 PolarHBondContact O-N 3.22Å
193T89.3Confident91.5Very high82 Ų8237.8 Ų37.850%0.50321%0.207SC..THydrogen-bonded Turntrans-78.14.1173.1680000114.5D189 L190 K191D189-T193 WeakPolarHBondContact O-CG2 3.36Å; D189-T193 PolarHBondContact O-N 3.3Å; D189-T193 VanDerWaalsContact O-N 3.16Å; L190-T193 PolarHBondContact O-N 2.92Å; L190-T193 VanDerWaalsContact O-N 3.11Å; L190-T193 PolarHBondContact O-OG1 3.25Å; K191-T193 VanDerWaalsContact C-N 3.26Å; K191-T193 PolarHBondContact O-N 2.96Å
194G87.4Confident90.9Very high51 Ų5140.5 Ų40.553%0.52622%0.218SC..THydrogen-bonded Turntrans83.518.3178.900000114.6L190 K191 E192L190-G194 PolarHBondContact O-N 3.39Å; K191-G194 PolarHBondContact O-N 3.27Å; E192-G194 PolarHBondContact O-N 3.22Å
195V91.1Very high90Very high2 Ų243.1 Ų43.11%0.01225%0.245CC..EExtended strand (participates in β ladder)trans-82.4126.6174.2-177.50000109.6Y151 K161 L163 L190 I197Y151-V195 HydrophobicContact CD2-CG2 3.98Å; Y151-V195 HydrophobicContact CE2-CG1 3.89Å; Y151-V195 HydrophobicContact CE2-CG2 3.97Å; K161-V195 HydrophobicContact CB-CB 4.34Å; K161-V195 HydrophobicContact CB-CG1 4.47Å; K161-V195 HydrophobicContact CB-CG2 3.81Å; K161-V195 HydrophobicContact CD-CG2 3.89Å; K161-V195 WeakPolarHBondContact O-CA 3.32Å; L163-V195 HydrophobicContact CB-CG1 4.03Å; L190-V195 HydrophobicContact CB-CB 4.31Å; L190-V195 HydrophobicContact CD2-CB 4.36Å; L190-V195 HydrophobicContact CD2-CG2 3.98Å; L190-V195 WeakPolarHBondContact O-CB 3.21Å; L190-V195 PolarHBondContact O-N 3.1Å; L190-V195 VanDerWaalsContact O-N 3.14Å; V195-I197 HydrophobicContact CG1-CG1 4.45Å
196L90.7Very high89.2Confident39 Ų3944.1 Ų44.120%0.20427%0.269CS..EExtended strand (participates in β ladder)trans-86.5122.1170.9-63.8178000109.4K161 R162 L163K161-L196 PolarHBondContact O-N 2.88Å; R162-L196 CarbonylContact C-O 3.52Å; R162-L196 WeakPolarHBondContact CA-O 3.46Å; L163-L196 PolarHBondContact N-O 3.3Å
197I92.4Very high88.8Confident0 Ų043 Ų430%027%0.273CS..EExtended strand (participates in β ladder)trans-103.3117.7179-55178.4000108.4L163 I165 A187 L190 K191 V195 I217 V218 S219L163-I197 HydrophobicContact CB-CG1 4.43Å; L163-I197 HydrophobicContact CD2-CG1 4.29Å; L163-I197 HydrophobicContact CD2-CG2 4.36Å; L163-I197 CarbonylContact O-C 3.54Å; L163-I197 WeakPolarHBondContact O-CA 3.36Å; I165-I197 HydrophobicContact CD1-CG2 3.7Å; I165-I197 HydrophobicContact CG1-CG2 4.21Å; A187-I197 HydrophobicContact CB-CD1 4.07Å; L190-I197 HydrophobicContact CB-CD1 4.12Å; L190-I197 HydrophobicContact CD1-CD1 4.21Å; K191-I197 HydrophobicContact CG-CD1 4.2Å; K191-I197 HydrophobicContact CG-CG1 4.5Å; V195-I197 HydrophobicContact CG1-CG1 4.45Å; I197-I217 HydrophobicContact CG2-CG2 4.27Å; I197-V218 VanDerWaalsContact O-CG1 3.25Å; I197-V218 WeakPolarHBondContact O-CG1 3.32Å; I197-S219 PolarHBondContact N-OG 2.93Å; I197-S219 PolarHBondContact O-N 2.59Å
198D90.5Very high88.5Confident6 Ų644 Ų443%0.03228%0.277CS..EExtended strand (participates in β ladder)trans-110.8139.1176.5-65.1-55.4000110.8R162 L163 M164 I165 M200 R247R162-D198 WeakPolarHBondContact CD-OD2 2.88Å; R162-D198 WeakPolarHBondContact CG-OD2 3.48Å; R162-D198 IonicContact CZ-OD2 3.6Å; R162-D198 IonicContact NE-OD2 3.29Å; R162-D198 IonicContact NH1-OD1 3.92Å; R162-D198 IonicContact NH1-OD2 2.72Å; R162-D198 PolarHBondContact NH1-OD2 3.16Å; L163-D198 PolarHBondContact O-N 3.37Å; M164-D198 WeakPolarHBondContact CA-O 3.12Å; M164-D198 HydrophobicContact CG-CB 4.23Å; I165-D198 PolarHBondContact N-O 3.01Å; D198-M200 HydrophobicContact CB-CE 3.82Å; D198-R247 WeakPolarHBondContact OD1-CD 3.4Å; D198-R247 IonicContact OD1-CZ 2.8Å; D198-R247 IonicContact OD1-NE 3.72Å; D198-R247 IonicContact OD1-NH1 2.61Å; D198-R247 PolarHBondContact OD1-NH1 3.06Å
199L90.5Very high88.1Confident14 Ų1445 Ų457%0.07328%0.278CS..EExtended strand (participates in β ladder)trans-103.3121.9175178.467.3000111.1I165 T167 H201 F208 V210 F214 V218I165-L199 HydrophobicContact CB-CD1 4.21Å; I165-L199 HydrophobicContact CG2-CD1 4.21Å; T167-L199 HydrophobicContact CG2-CD1 3.97Å; L199-H201 HydrophobicContact CD1-CB 4.37Å; L199-H201 HydrophobicContact CD2-CB 3.96Å; L199-H201 HydrophobicContact CG-CB 3.92Å; L199-F208 HydrophobicContact CD2-CE1 3.92Å; L199-F208 HydrophobicContact CD2-CZ 4.12Å; L199-V210 HydrophobicContact CD2-CG1 4.46Å; L199-V210 HydrophobicContact CD2-CG2 4.36Å; L199-F214 HydrophobicContact CD1-CD1 3.85Å; L199-F214 HydrophobicContact CD1-CE1 3.93Å; L199-F214 HydrophobicContact CD1-CG 4.22Å; L199-F214 HydrophobicContact CD1-CZ 4.37Å; L199-F214 HydrophobicContact CD2-CB 3.67Å; L199-F214 HydrophobicContact CD2-CD1 4.09Å; L199-F214 HydrophobicContact CD2-CD2 4.26Å; L199-F214 HydrophobicContact CD2-CG 3.73Å; L199-F214 HydrophobicContact CG-CD1 4.49Å; L199-V218 HydrophobicContact CB-CG2 3.56Å; L199-V218 HydrophobicContact CD2-CG2 4.35Å
200M91.2Very high87.8Confident0 Ų043.6 Ų43.60%027%0.272CS..EExtended strand (participates in β ladder)trans-102.175.2168.7-58.7-57.3120.200108.3I165 F166 T167 D198 L240 R243 V244I165-M200 WeakPolarHBondContact O-CA 3.44Å; I165-M200 WeakPolarHBondContact O-CB 3.23Å; I165-M200 PolarHBondContact O-N 3.39Å; F166-M200 HydrophobicContact CD1-CB 3.54Å; F166-M200 HydrophobicContact CD1-CG 4.06Å; F166-M200 HydrophobicContact CD2-CB 4.43Å; F166-M200 HydrophobicContact CE1-CB 3.65Å; F166-M200 HydrophobicContact CE1-CG 3.65Å; F166-M200 HydrophobicContact CE2-CB 4.47Å; F166-M200 HydrophobicContact CE2-CG 4.11Å; F166-M200 HydrophobicContact CG-CB 3.97Å; F166-M200 HydrophobicContact CG-CG 4.48Å; F166-M200 HydrophobicContact CZ-CB 4.13Å; F166-M200 HydrophobicContact CZ-CG 3.68Å; T167-M200 PolarHBondContact N-O 3.19Å; D198-M200 HydrophobicContact CB-CE 3.82Å; M200-L240 HydrophobicContact CB-CD1 4.11Å; M200-R243 HydrophobicContact CE-CG 4.24Å; M200-R243 HydrophobicContact SD-CB 4.32Å; M200-R243 HydrophobicContact SD-CG 3.69Å; M200-V244 HydrophobicContact CG-CG2 4.1Å; M200-V244 HydrophobicContact SD-CG2 3.92Å
201H88.9Confident87.5Confident4 Ų446.7 Ų46.72%0.01929%0.294CS..EExtended strand (participates in β ladder)trans-75.7130.5-179.454.4104.6000111.3T167 L199 F208 E232 P233 C234T167-H201 WeakPolarHBondContact O-CA 3.47Å; L199-H201 HydrophobicContact CD1-CB 4.37Å; L199-H201 HydrophobicContact CD2-CB 3.96Å; L199-H201 HydrophobicContact CG-CB 3.92Å; H201-F208 HydrophobicContact CB-CD1 3.65Å; H201-F208 HydrophobicContact CB-CD2 3.82Å; H201-F208 HydrophobicContact CB-CE1 3.56Å; H201-F208 HydrophobicContact CB-CE2 3.69Å; H201-F208 HydrophobicContact CB-CG 3.81Å; H201-F208 HydrophobicContact CB-CZ 3.58Å; H201-F208 AromaticContact CG-CD1 3.94Å; H201-F208 AromaticContact ND1-CD1 3.92Å; H201-E232 PolarHBondContact CE1-O 3.05Å; H201-P233 VanDerWaalsContact CE1-N 3.33Å; H201-P233 WeakPolarHBondContact ND1-CA 3.29Å; H201-P233 WeakPolarHBondContact O-CA 3.36Å; H201-C234 PolarHBondContact O-N 3.28Å
202L89.3Confident87.3Confident0 Ų048.4 Ų48.40%031%0.306CS..BIsolated β-bridgetrans-105.8155.2-174.7-57.3172.5000110.5M45 N56 T167 C168 C234 L240M45-L202 HydrophobicContact CE-CD1 3.67Å; M45-L202 HydrophobicContact SD-CD1 4.01Å; N56-L202 HydrophobicContact CB-CB 4.32Å; N56-L202 HydrophobicContact CB-CD1 3.71Å; T167-L202 PolarHBondContact O-N 2.98Å; C168-L202 HydrophobicContact CB-CB 4.16Å; L202-C234 HydrophobicContact CD2-CB 4.17Å; L202-L240 HydrophobicContact CD2-CD1 3.94Å; L202-L240 HydrophobicContact CD2-CD2 3.88Å; L202-L240 HydrophobicContact CD2-CG 4.49Å
203I86.2Confident87.2Confident75 Ų7541.2 Ų41.239%0.38527%0.272SS..  trans-66.5139.6-176.8-161.2159000111.9N56 P233 C234 D235N56-I203 PolarHBondContact ND2-O 3.11Å; I203-P233 HydrophobicContact CB-CB 4.41Å; I203-C234 PolarHBondContact N-O 3.35Å; I203-D235 HydrophobicContact CB-CB 4.3Å; I203-D235 HydrophobicContact CD1-CB 3.87Å; I203-D235 HydrophobicContact CG2-CB 4.08Å
204K81.5Confident87.2Confident56 Ų5637.3 Ų37.324%0.24325%0.248CC..  trans-131.7159.3167.268.2162.1-180177.30110.2C168 D170 G206 G207C168-K204 HydrophobicContact CB-CB 4.39Å; C168-K204 WeakPolarHBondContact O-CD 3.48Å; D170-K204 IonicContact OD1-NZ 2.69Å; D170-K204 PolarHBondContact OD1-NZ 3.11Å; D170-K204 VanDerWaalsContact OD2-CE 3.24Å; D170-K204 WeakPolarHBondContact OD2-CE 3.36Å; D170-K204 IonicContact OD2-NZ 3.18Å; D170-K204 PolarHBondContact OD2-NZ 2.97Å; K204-G206 PolarHBondContact O-N 3.14Å; K204-G207 WeakPolarHBondContact CE-O 3.26Å; K204-G207 WeakPolarHBondContact CG-O 3.45Å; K204-G207 PolarHBondContact O-N 3.34Å
205P75.6Confident87.3Confident130 Ų13043.7 Ų43.784%0.84426%0.256SS*.THydrogen-bonded Turntrans-55.6121.6167.8-22.633.7000110.2
206G77.1Confident87.1Confident89 Ų8947.6 Ų47.692%0.91828%0.277SS*.THydrogen-bonded Turntrans97.10.9-175.700000115.7K204K204-G206 PolarHBondContact O-N 3.14Å
207G84.8Confident87.1Confident30 Ų3045.7 Ų45.731%0.30927%0.267SS..  trans82.9-176.8177.800000113.3K204K204-G207 WeakPolarHBondContact CE-O 3.26Å; K204-G207 WeakPolarHBondContact CG-O 3.45Å; K204-G207 PolarHBondContact O-N 3.34Å
208F88.7Confident86.9Confident22 Ų2246.2 Ų46.210%0.09627%0.27CS..  trans-130118.7179.3-172.4-72.8000109.5T167 R169 D170 L199 H201 V210 F214 P233T167-F208 HydrophobicContact CG2-CE2 4.27Å; T167-F208 HydrophobicContact CG2-CZ 4.39Å; R169-F208 VanDerWaalsContact C-CE2 3.43Å; R169-F208 WeakPolarHBondContact O-CE2 3.35Å; D170-F208 HydrophobicContact CB-CD1 4.15Å; D170-F208 HydrophobicContact CB-CD2 4.18Å; D170-F208 HydrophobicContact CB-CE1 4.05Å; D170-F208 HydrophobicContact CB-CE2 4.11Å; D170-F208 HydrophobicContact CB-CG 4.2Å; D170-F208 HydrophobicContact CB-CZ 4.03Å; L199-F208 HydrophobicContact CD2-CE1 3.92Å; L199-F208 HydrophobicContact CD2-CZ 4.12Å; H201-F208 HydrophobicContact CB-CD1 3.65Å; H201-F208 HydrophobicContact CB-CD2 3.82Å; H201-F208 HydrophobicContact CB-CE1 3.56Å; H201-F208 HydrophobicContact CB-CE2 3.69Å; H201-F208 HydrophobicContact CB-CG 3.81Å; H201-F208 HydrophobicContact CB-CZ 3.58Å; H201-F208 AromaticContact CG-CD1 3.94Å; H201-F208 AromaticContact ND1-CD1 3.92Å; F208-V210 HydrophobicContact CD1-CG2 3.95Å; F208-V210 HydrophobicContact CE1-CG2 3.96Å; F208-F214 HydrophobicContact CE1-CD2 4.21Å; F208-F214 AromaticContact CZ-CD2 3.83Å; F208-F214 HydrophobicContact CZ-CD2 3.83Å; F208-F214 AromaticContact CZ-CE2 3.97Å; F208-F214 HydrophobicContact CZ-CE2 3.97Å; F208-P233 HydrophobicContact CB-CB 3.99Å; F208-P233 HydrophobicContact CB-CG 4.23Å
209D86.4Confident86.7Confident69 Ų6946.4 Ų46.437%0.36927%0.272SS..  trans-102.6104.2179.7-170.8-10.8000112.1D170 S211 L212D170-D209 WeakPolarHBondContact CB-O 3.48Å; D170-D209 PolarHBondContact OD2-N 2.84Å; D209-S211 VanDerWaalsContact CG-OG 3.28Å; D209-S211 PolarHBondContact O-N 3.36Å; D209-S211 VanDerWaalsContact OD1-CB 3.24Å; D209-S211 WeakPolarHBondContact OD1-CB 3.41Å; D209-S211 PolarHBondContact OD1-N 3.11Å; D209-S211 PolarHBondContact OD1-OG 2.98Å; D209-S211 PolarHBondContact OD2-OG 2.91Å; D209-L212 HydrophobicContact CB-CD1 3.88Å; D209-L212 HydrophobicContact CB-CG 3.9Å
210V86.8Confident85.9Confident30 Ų3050.4 Ų50.418%0.18230%0.299CS..THydrogen-bonded Turntrans-63.5-27.5178.6-177.30000112L199 F208 L212 F214 R215L199-V210 HydrophobicContact CD2-CG1 4.46Å; L199-V210 HydrophobicContact CD2-CG2 4.36Å; F208-V210 HydrophobicContact CD1-CG2 3.95Å; F208-V210 HydrophobicContact CE1-CG2 3.96Å; V210-L212 VanDerWaalsContact C-N 3.28Å; V210-L212 PolarHBondContact O-N 3.42Å; V210-F214 HydrophobicContact CG1-CB 4.09Å; V210-F214 PolarHBondContact O-N 3.11Å; V210-R215 PolarHBondContact O-N 3.45Å
211S86.6Confident84.7Confident70 Ų7052.1 Ų52.149%0.4931%0.31SS..THydrogen-bonded Turntrans-70.9-22.3-173.176.50000113.7D209D209-S211 VanDerWaalsContact CG-OG 3.28Å; D209-S211 PolarHBondContact O-N 3.36Å; D209-S211 VanDerWaalsContact OD1-CB 3.24Å; D209-S211 WeakPolarHBondContact OD1-CB 3.41Å; D209-S211 PolarHBondContact OD1-N 3.11Å; D209-S211 PolarHBondContact OD1-OG 2.98Å; D209-S211 PolarHBondContact OD2-OG 2.91Å
212L87.1Confident83.5Confident94 Ų9456.9 Ų56.949%0.49233%0.332SS..THydrogen-bonded Turntrans-65.1-43.4-178.9-62.5178.4000112.2D170 R184 D209 V210D170-L212 HydrophobicContact CB-CD1 4.39Å; R184-L212 PolarHBondContact NH2-O 3.36Å; D209-L212 HydrophobicContact CB-CD1 3.88Å; D209-L212 HydrophobicContact CB-CG 3.9Å; V210-L212 VanDerWaalsContact C-N 3.28Å; V210-L212 PolarHBondContact O-N 3.42Å
213F89.6Confident81.9Confident2 Ų258.3 Ų58.31%0.00934%0.34CS..THydrogen-bonded Turntrans-143.9-51.4-171.7178.6-97.2000113.7L140 D170 P172 H173 D180 A183 R184 R215 I217L140-F213 HydrophobicContact CD2-CE1 3.51Å; L140-F213 HydrophobicContact CD2-CZ 3.98Å; D170-F213 WeakPolarHBondContact O-CB 3.32Å; P172-F213 HydrophobicContact CG-CD1 3.67Å; P172-F213 HydrophobicContact CG-CE1 3.6Å; P172-F213 HydrophobicContact CG-CG 4.24Å; P172-F213 HydrophobicContact CG-CZ 4.12Å; H173-F213 AromaticContact CE1-CZ 3.81Å; H173-F213 AromaticContact ND1-CE2 3.99Å; D180-F213 HydrophobicContact CB-CD2 4.45Å; D180-F213 HydrophobicContact CB-CE2 4.06Å; D180-F213 WeakPolarHBondContact OD1-CD2 3.26Å; D180-F213 WeakPolarHBondContact OD1-CE2 3.25Å; A183-F213 HydrophobicContact CB-CE2 4.41Å; A183-F213 HydrophobicContact CB-CZ 3.78Å; R184-F213 HydrophobicContact CG-CE2 4.42Å; F213-R215 VanDerWaalsContact C-N 3.3Å; F213-R215 PolarHBondContact O-N 2.96Å; F213-I217 HydrophobicContact CD1-CG1 4.11Å; F213-I217 HydrophobicContact CE1-CD1 4.04Å; F213-I217 HydrophobicContact CE1-CG1 3.58Å; F213-I217 HydrophobicContact CZ-CD1 3.84Å; F213-I217 HydrophobicContact CZ-CG1 3.9Å
214F89.9Confident80.3Confident0 Ų061.6 Ų61.60%036%0.358CS..G310 helixtrans-71.2-19.6-169.1-77.5-81000115L140 I165 T167 R169 P172 L199 F208 V210 D216 I217 V218L140-F214 HydrophobicContact CD2-CE1 4.04Å; L140-F214 HydrophobicContact CD2-CZ 4.31Å; I165-F214 HydrophobicContact CD1-CE1 4.4Å; I165-F214 HydrophobicContact CG2-CE1 4.3Å; T167-F214 HydrophobicContact CG2-CE2 4.24Å; T167-F214 HydrophobicContact CG2-CZ 3.84Å; R169-F214 VanDerWaalsContact O-CE2 3.24Å; R169-F214 WeakPolarHBondContact O-CE2 3.04Å; P172-F214 HydrophobicContact CG-CE2 4.38Å; P172-F214 HydrophobicContact CG-CZ 4.31Å; L199-F214 HydrophobicContact CD1-CD1 3.85Å; L199-F214 HydrophobicContact CD1-CE1 3.93Å; L199-F214 HydrophobicContact CD1-CG 4.22Å; L199-F214 HydrophobicContact CD1-CZ 4.37Å; L199-F214 HydrophobicContact CD2-CB 3.67Å; L199-F214 HydrophobicContact CD2-CD1 4.09Å; L199-F214 HydrophobicContact CD2-CD2 4.26Å; L199-F214 HydrophobicContact CD2-CG 3.73Å; L199-F214 HydrophobicContact CG-CD1 4.49Å; F208-F214 HydrophobicContact CE1-CD2 4.21Å; F208-F214 AromaticContact CZ-CD2 3.83Å; F208-F214 HydrophobicContact CZ-CD2 3.83Å; F208-F214 AromaticContact CZ-CE2 3.97Å; F208-F214 HydrophobicContact CZ-CE2 3.97Å; V210-F214 HydrophobicContact CG1-CB 4.09Å; V210-F214 PolarHBondContact O-N 3.11Å; F214-D216 PolarHBondContact O-N 3.02Å; F214-D216 VanDerWaalsContact O-N 3.12Å; F214-I217 HydrophobicContact CD1-CB 4.26Å; F214-I217 HydrophobicContact CD1-CG1 4.49Å; F214-I217 HydrophobicContact CD1-CG2 4.33Å; F214-I217 PolarHBondContact O-N 3.22Å; F214-V218 HydrophobicContact CB-CG2 4.27Å; F214-V218 WeakPolarHBondContact O-CG2 3.36Å; F214-V218 PolarHBondContact O-N 3.31Å
215R87.6Confident78.9Confident185 Ų18560.1 Ų60.170%0.69836%0.355SS*.G310 helixtrans-49.6-38.3175.9-179-179.6176.4-176.6-0.4113.1V210 F213V210-R215 PolarHBondContact O-N 3.45Å; F213-R215 VanDerWaalsContact C-N 3.3Å; F213-R215 PolarHBondContact O-N 2.96Å
216D86.9Confident77.9Confident84 Ų8455.6 Ų55.645%0.44932%0.322SS..G310 helixtrans-91.3-12.1-178-60.6-56.4000113R184 K191 F214R184-D216 IonicContact CZ-OD2 3.96Å; R184-D216 VanDerWaalsContact NH1-CG 3.32Å; R184-D216 IonicContact NH1-OD2 3.45Å; R184-D216 PolarHBondContact NH1-OD2 3.25Å; K191-D216 PolarHBondContact NZ-O 3.27Å; F214-D216 PolarHBondContact O-N 3.02Å; F214-D216 VanDerWaalsContact O-N 3.12Å
217I90.5Very high76.6Confident0 Ų056.1 Ų56.10%030%0.303CS..THydrogen-bonded Turntrans-85.7-53.6179.1-59-61.5000110.6I165 R184 A187 K191 I197 F213 F214I165-I217 HydrophobicContact CD1-CG2 4.21Å; R184-I217 HydrophobicContact CB-CD1 4.42Å; R184-I217 HydrophobicContact CG-CD1 3.96Å; A187-I217 HydrophobicContact CB-CB 4.33Å; A187-I217 HydrophobicContact CB-CD1 3.64Å; A187-I217 HydrophobicContact CB-CG2 3.94Å; K191-I217 PolarHBondContact NZ-O 3.08Å; K191-I217 VanDerWaalsContact NZ-O 3.13Å; I197-I217 HydrophobicContact CG2-CG2 4.27Å; F213-I217 HydrophobicContact CD1-CG1 4.11Å; F213-I217 HydrophobicContact CE1-CD1 4.04Å; F213-I217 HydrophobicContact CE1-CG1 3.58Å; F213-I217 HydrophobicContact CZ-CD1 3.84Å; F213-I217 HydrophobicContact CZ-CG1 3.9Å; F214-I217 HydrophobicContact CD1-CB 4.26Å; F214-I217 HydrophobicContact CD1-CG1 4.49Å; F214-I217 HydrophobicContact CD1-CG2 4.33Å; F214-I217 PolarHBondContact O-N 3.22Å
218V89.2Confident74.6Confident11 Ų1156.1 Ų56.17%0.06730%0.303CS..SBendtrans-62146.5-173.3-174.90000110.4K191 I197 L199 F214 Q230K191-V218 PolarHBondContact NZ-O 3.19Å; I197-V218 VanDerWaalsContact O-CG1 3.25Å; I197-V218 WeakPolarHBondContact O-CG1 3.32Å; L199-V218 HydrophobicContact CB-CG2 3.56Å; L199-V218 HydrophobicContact CD2-CG2 4.35Å; F214-V218 HydrophobicContact CB-CG2 4.27Å; F214-V218 WeakPolarHBondContact O-CG2 3.36Å; F214-V218 PolarHBondContact O-N 3.31Å; V218-Q230 VanDerWaalsContact CG1-NE2 3.26Å
219S85.9Confident72.8Confident10 Ų1056.1 Ų56.17%0.0730%0.304CS..PPolyproline II helixtrans-68.8141.1174.5-70.10000110.1I197I197-S219 PolarHBondContact N-OG 2.93Å; I197-S219 PolarHBondContact O-N 2.59Å
220P73.4Confident71.2Confident98 Ų9855.5 Ų55.564%0.63630%0.299SS*.PPolyproline II helixtrans-61.5146.2173.328.2-33.8000109.4
221P67Low70Confident35 Ų3559.8 Ų59.823%0.22732%0.32CS..PPolyproline II helixtrans-57.8139.2176.422.3-30.4000111D223 E226 L227P221-D223 WeakPolarHBondContact CB-O 3.32Å; P221-D223 PolarHBondContact O-N 3.37Å; P221-E226 WeakPolarHBondContact CA-OE2 3.47Å; P221-E226 HydrophobicContact CB-CB 3.33Å; P221-L227 HydrophobicContact CG-CB 4.5Å; P221-L227 HydrophobicContact CG-CD1 3.7Å; P221-L227 HydrophobicContact CG-CG 3.81Å
222E63.1Low69.3Low104 Ų10461.4 Ų61.449%0.48632%0.321SS..SBendtrans-69.4-23176.6-71.4-169.6167.500111.2E226 K250E222-E226 PolarHBondContact N-OE2 3.13Å; E222-K250 IonicContact OE1-NZ 3.72Å; E222-K250 PolarHBondContact OE1-NZ 3.39Å; E222-K250 WeakPolarHBondContact OE2-CE 3.21Å; E222-K250 IonicContact OE2-NZ 2.68Å; E222-K250 PolarHBondContact OE2-NZ 3.13Å
223D57.2Low69Low30 Ų3058.7 Ų58.716%0.1631%0.308CS..SBendtrans-147.9166.8177.362.840.4000113.7P221 S225 E226 K251P221-D223 WeakPolarHBondContact CB-O 3.32Å; P221-D223 PolarHBondContact O-N 3.37Å; D223-S225 VanDerWaalsContact CG-OG 3.24Å; D223-S225 PolarHBondContact O-N 2.71Å; D223-S225 VanDerWaalsContact O-N 3.12Å; D223-S225 WeakPolarHBondContact OD1-CA 3.39Å; D223-S225 WeakPolarHBondContact OD1-CB 3.49Å; D223-S225 PolarHBondContact OD1-N 2.95Å; D223-S225 PolarHBondContact OD1-OG 3.16Å; D223-S225 PolarHBondContact OD2-OG 2.87Å; D223-E226 PolarHBondContact O-N 3.26Å; D223-E226 VanDerWaalsContact O-N 3.08Å; D223-E226 PolarHBondContact OD1-N 3.49Å; D223-K251 IonicContact OD2-NZ 3.54Å; D223-K251 PolarHBondContact OD2-NZ 3.04Å
224D51.9Low68.6Low144 Ų14458.7 Ų58.777%0.7731%0.308SS*.THydrogen-bonded Turntrans-61.3-19.1179-68.6-18.9000113.4L227D224-L227 WeakPolarHBondContact O-CB 3.31Å; D224-L227 PolarHBondContact O-N 3.46Å
225S52.4Low68.2Low25 Ų2562.2 Ų62.218%0.17533%0.327CS..THydrogen-bonded Turntrans-77.1-26176.972.30000112.6D223D223-S225 VanDerWaalsContact CG-OG 3.24Å; D223-S225 PolarHBondContact O-N 2.71Å; D223-S225 VanDerWaalsContact O-N 3.12Å; D223-S225 WeakPolarHBondContact OD1-CA 3.39Å; D223-S225 WeakPolarHBondContact OD1-CB 3.49Å; D223-S225 PolarHBondContact OD1-N 2.95Å; D223-S225 PolarHBondContact OD1-OG 3.16Å; D223-S225 PolarHBondContact OD2-OG 2.87Å
226E53.4Low68.1Low36 Ų3658.8 Ų58.817%0.16832%0.318CS..THydrogen-bonded Turntrans-79.4-17.2173.9-73-179.6-177.300113.2P221 E222 D223 G228 L229P221-E226 WeakPolarHBondContact CA-OE2 3.47Å; P221-E226 HydrophobicContact CB-CB 3.33Å; E222-E226 PolarHBondContact N-OE2 3.13Å; D223-E226 PolarHBondContact O-N 3.26Å; D223-E226 VanDerWaalsContact O-N 3.08Å; D223-E226 PolarHBondContact OD1-N 3.49Å; E226-G228 VanDerWaalsContact C-N 3.27Å; E226-G228 PolarHBondContact O-N 2.83Å; E226-L229 PolarHBondContact O-N 2.82Å
227L49.5Very low68.1Low99 Ų9956.7 Ų56.752%0.51831%0.306SS..G310 helixtrans-61.1-33.8173.7-104.5114.2000112.3P221 D224 L229P221-L227 HydrophobicContact CG-CB 4.5Å; P221-L227 HydrophobicContact CG-CD1 3.7Å; P221-L227 HydrophobicContact CG-CG 3.81Å; D224-L227 WeakPolarHBondContact O-CB 3.31Å; D224-L227 PolarHBondContact O-N 3.46Å; L227-L229 VanDerWaalsContact C-N 3.32Å; L227-L229 PolarHBondContact O-N 3.23Å
228G42.8Very low67.8Low30 Ų3062.4 Ų62.431%0.30933%0.333SS..G310 helixtrans-71.5-22.6-178.100000114.7E226 Q230 K422E226-G228 VanDerWaalsContact C-N 3.27Å; E226-G228 PolarHBondContact O-N 2.83Å; G228-Q230 PolarHBondContact O-N 2.83Å; G228-K422 WeakPolarHBondContact O-CB 3.49Å
229L51.3Low67.4Low22 Ų2263.8 Ų63.812%0.11534%0.34CS..G310 helixtrans-82.4-5.1-171.3-73.9169.3000114.8E226 L227 K422 V423E226-L229 PolarHBondContact O-N 2.82Å; L227-L229 VanDerWaalsContact C-N 3.32Å; L227-L229 PolarHBondContact O-N 3.23Å; L229-K422 WeakPolarHBondContact CD2-O 3.43Å; L229-V423 HydrophobicContact CD2-CB 4.34Å; L229-V423 HydrophobicContact CD2-CG1 4.49Å; L229-V423 HydrophobicContact CD2-CG2 4.12Å
230Q54.1Low67.5Low57 Ų5763.3 Ų63.327%0.26634%0.336SS..G310 helixtrans-99.75.6-168.9-85.9-175-10.200116.2V218 G228V218-Q230 VanDerWaalsContact CG1-NE2 3.26Å; G228-Q230 PolarHBondContact O-N 2.83Å
231L60Low68.1Low119 Ų11961 Ų6162%0.62332%0.317SS*.SBendtrans-105.1-14.3-159.5-74156.1000116.7
232E72.4Confident68.8Low105 Ų10562.6 Ų62.649%0.49132%0.321SS..SBendtrans-136.7134.8-176-69.5175-14200114.2H201 R243 K422H201-E232 PolarHBondContact CE1-O 3.05Å; E232-R243 PolarHBondContact O-NH1 3.32Å; E232-R243 PolarHBondContact O-NH2 2.91Å; E232-K422 IonicContact OE1-NZ 3.84Å; E232-K422 PolarHBondContact OE1-NZ 3.3Å
233P80.1Confident69.7Low36 Ų3658.5 Ų58.523%0.23430%0.301CS..  trans-65.5141.1179.526.5-32.5000111.8H201 I203 F208H201-P233 VanDerWaalsContact CE1-N 3.33Å; H201-P233 WeakPolarHBondContact ND1-CA 3.29Å; H201-P233 WeakPolarHBondContact O-CA 3.36Å; I203-P233 HydrophobicContact CB-CB 4.41Å; F208-P233 HydrophobicContact CB-CB 3.99Å; F208-P233 HydrophobicContact CB-CG 4.23Å
234C82.8Confident71.2Confident2 Ų257 Ų571%0.01429%0.293CS..BIsolated β-bridgetrans-73.5127.9175.1-66.60000110.4H201 L202 I203 L240 R243H201-C234 PolarHBondContact O-N 3.28Å; L202-C234 HydrophobicContact CD2-CB 4.17Å; I203-C234 PolarHBondContact N-O 3.35Å; C234-L240 HydrophobicContact CB-CB 4.27Å; C234-L240 HydrophobicContact CB-CD1 4.31Å; C234-R243 PolarHBondContact SG-NE 3.31Å; C234-R243 PolarHBondContact SG-NH1 3.36Å; C234-R243 VanDerWaalsContact SG-NH1 3.41Å
235D81.3Confident72.6Confident74 Ų7455.8 Ų55.840%0.39628%0.277SS..  trans-104.7-29.5172.167.4-22.6000112.5I203I203-D235 HydrophobicContact CB-CB 4.3Å; I203-D235 HydrophobicContact CD1-CB 3.87Å; I203-D235 HydrophobicContact CG2-CB 4.08Å
236K85Confident73.9Confident114 Ų11457.2 Ų57.250%0.49629%0.29SS..SBendtrans-110146.6-175.8-69165.9-166.51670112.8M59 E238 D239 L240M59-K236 VanDerWaalsContact CE-C 3.47Å; K236-E238 VanDerWaalsContact C-N 3.33Å; K236-E238 PolarHBondContact O-N 3.12Å; K236-D239 PolarHBondContact O-N 3.2Å; K236-L240 PolarHBondContact O-N 2.71Å; K236-L240 VanDerWaalsContact O-N 3.12Å
237L85.9Confident75.1Confident39 Ų3956.2 Ų56.220%0.20429%0.285CS..Hα-helixtrans-58.5-43.7174.6177.165.5000112.1M59 Q62 V63 D239 L240 Q241M59-L237 HydrophobicContact CB-CD1 4.42Å; Q62-L237 HydrophobicContact CB-CD1 3.86Å; V63-L237 HydrophobicContact CG2-CD1 3.72Å; L237-D239 VanDerWaalsContact C-N 3.3Å; L237-D239 PolarHBondContact O-N 3.25Å; L237-L240 PolarHBondContact O-N 3.08Å; L237-Q241 HydrophobicContact CD1-CG 4.23Å; L237-Q241 HydrophobicContact CG-CG 4.36Å; L237-Q241 WeakPolarHBondContact O-CB 3.13Å; L237-Q241 WeakPolarHBondContact O-CG 3.27Å; L237-Q241 PolarHBondContact O-N 2.78Å
238E84.2Confident76.5Confident120 Ų12052.5 Ų52.556%0.56127%0.265SS*.Hα-helixtrans-60.5-41-178.1-63.2-174.8-176.300111.7K236 Q241 K242K236-E238 VanDerWaalsContact C-N 3.33Å; K236-E238 PolarHBondContact O-N 3.12Å; E238-Q241 PolarHBondContact O-N 3.3Å; E238-K242 WeakPolarHBondContact O-CG 3.35Å; E238-K242 PolarHBondContact O-N 3.01Å
239D82.6Confident77.9Confident40 Ų4054.5 Ų54.521%0.21427%0.271CS..Hα-helixtrans-74.7-36.5-178.6-61.9-34.6000111.4K236 L237 K242 R243K236-D239 PolarHBondContact O-N 3.2Å; L237-D239 VanDerWaalsContact C-N 3.3Å; L237-D239 PolarHBondContact O-N 3.25Å; D239-K242 PolarHBondContact O-N 3.31Å; D239-K242 IonicContact OD1-NZ 2.84Å; D239-K242 PolarHBondContact OD1-NZ 3.43Å; D239-R243 WeakPolarHBondContact O-CB 3.39Å; D239-R243 PolarHBondContact O-N 3.43Å
240L86.6Confident78.9Confident0 Ų056 Ų560%028%0.277CS..Hα-helixtrans-62.1-42.9170-173.863.3000111.6M59 V63 F166 M200 L202 C234 K236 L237 R243 V244M59-L240 HydrophobicContact CB-CD2 4.27Å; M59-L240 HydrophobicContact CE-CD2 4.31Å; V63-L240 HydrophobicContact CB-CD2 4.48Å; V63-L240 HydrophobicContact CG2-CB 4.28Å; V63-L240 HydrophobicContact CG2-CD2 3.76Å; V63-L240 HydrophobicContact CG2-CG 3.84Å; F166-L240 HydrophobicContact CD1-CD1 4.37Å; F166-L240 HydrophobicContact CE1-CD1 4.09Å; M200-L240 HydrophobicContact CB-CD1 4.11Å; L202-L240 HydrophobicContact CD2-CD1 3.94Å; L202-L240 HydrophobicContact CD2-CD2 3.88Å; L202-L240 HydrophobicContact CD2-CG 4.49Å; C234-L240 HydrophobicContact CB-CB 4.27Å; C234-L240 HydrophobicContact CB-CD1 4.31Å; K236-L240 PolarHBondContact O-N 2.71Å; K236-L240 VanDerWaalsContact O-N 3.12Å; L237-L240 PolarHBondContact O-N 3.08Å; L240-R243 PolarHBondContact O-N 2.97Å; L240-V244 HydrophobicContact CD1-CG2 4.38Å; L240-V244 WeakPolarHBondContact O-CB 3.36Å; L240-V244 WeakPolarHBondContact O-CG2 3.48Å; L240-V244 PolarHBondContact O-N 3.14Å
241Q86.2Confident80.1Confident49 Ų4958.2 Ų58.223%0.22929%0.286CS..Hα-helixtrans-60.9-46.3175.8-76.8179.1-16.200111.8V63 L237 E238 V244 R245V63-Q241 HydrophobicContact CG2-CG 3.61Å; L237-Q241 HydrophobicContact CD1-CG 4.23Å; L237-Q241 HydrophobicContact CG-CG 4.36Å; L237-Q241 WeakPolarHBondContact O-CB 3.13Å; L237-Q241 WeakPolarHBondContact O-CG 3.27Å; L237-Q241 PolarHBondContact O-N 2.78Å; E238-Q241 PolarHBondContact O-N 3.3Å; Q241-V244 PolarHBondContact O-N 2.99Å; Q241-R245 WeakPolarHBondContact O-CB 3.5Å; Q241-R245 VanDerWaalsContact O-CG 3.27Å; Q241-R245 WeakPolarHBondContact O-CG 3.35Å; Q241-R245 PolarHBondContact O-N 2.81Å
242K82Confident81Confident70 Ų7058.8 Ų58.830%0.30428%0.28SS..Hα-helixtrans-60-46.1175.8-71.2171.9-167162.40111.6E238 D239 V244 R245 A246 D419E238-K242 WeakPolarHBondContact O-CG 3.35Å; E238-K242 PolarHBondContact O-N 3.01Å; D239-K242 PolarHBondContact O-N 3.31Å; D239-K242 IonicContact OD1-NZ 2.84Å; D239-K242 PolarHBondContact OD1-NZ 3.43Å; K242-V244 PolarHBondContact O-N 3.2Å; K242-R245 PolarHBondContact O-N 2.75Å; K242-A246 WeakPolarHBondContact O-CB 3.17Å; K242-A246 PolarHBondContact O-N 3.25Å; K242-D419 IonicContact NZ-OD2 3.02Å
243R82.9Confident81.6Confident17 Ų1755 Ų556%0.06427%0.266CS..Hα-helixtrans-63.7-42.7-178.5-168.6178.3-66.4-174.61.7112M200 E232 C234 D239 L240 R247M200-R243 HydrophobicContact CE-CG 4.24Å; M200-R243 HydrophobicContact SD-CB 4.32Å; M200-R243 HydrophobicContact SD-CG 3.69Å; E232-R243 PolarHBondContact O-NH1 3.32Å; E232-R243 PolarHBondContact O-NH2 2.91Å; C234-R243 PolarHBondContact SG-NE 3.31Å; C234-R243 PolarHBondContact SG-NH1 3.36Å; C234-R243 VanDerWaalsContact SG-NH1 3.41Å; D239-R243 WeakPolarHBondContact O-CB 3.39Å; D239-R243 PolarHBondContact O-N 3.43Å; L240-R243 PolarHBondContact O-N 2.97Å; R243-R247 PolarHBondContact O-N 2.8Å
244V87Confident81.9Confident0 Ų055.1 Ų55.10%027%0.265CS..Hα-helixtrans-66.8-47175.7171.80000110.7V63 V67 M164 F166 M200 L240 Q241 K242 A246 R247 E248V63-V244 HydrophobicContact CG1-CB 3.7Å; V63-V244 HydrophobicContact CG1-CG1 3.79Å; V63-V244 HydrophobicContact CG1-CG2 3.68Å; V67-V244 HydrophobicContact CG2-CG1 3.58Å; M164-V244 HydrophobicContact CE-CG1 4.5Å; M164-V244 HydrophobicContact SD-CG1 4.06Å; F166-V244 HydrophobicContact CE1-CG2 3.81Å; F166-V244 HydrophobicContact CZ-CG2 3.72Å; M200-V244 HydrophobicContact CG-CG2 4.1Å; M200-V244 HydrophobicContact SD-CG2 3.92Å; L240-V244 HydrophobicContact CD1-CG2 4.38Å; L240-V244 WeakPolarHBondContact O-CB 3.36Å; L240-V244 WeakPolarHBondContact O-CG2 3.48Å; L240-V244 PolarHBondContact O-N 3.14Å; Q241-V244 PolarHBondContact O-N 2.99Å; K242-V244 PolarHBondContact O-N 3.2Å; V244-A246 VanDerWaalsContact C-N 3.29Å; V244-A246 PolarHBondContact O-N 2.75Å; V244-R247 CarbonylContact O-C 3.58Å; V244-R247 PolarHBondContact O-N 3.01Å; V244-E248 WeakPolarHBondContact O-CB 3.28Å; V244-E248 PolarHBondContact O-N 3.31Å
245R82.6Confident82.1Confident118 Ų11856.1 Ų56.145%0.44527%0.273SS..Hα-helixtrans-58.4-39.6177.3-76.1177.6-176.9-179.93.1112.6Q241 K242 R247 E248Q241-R245 WeakPolarHBondContact O-CB 3.5Å; Q241-R245 VanDerWaalsContact O-CG 3.27Å; Q241-R245 WeakPolarHBondContact O-CG 3.35Å; Q241-R245 PolarHBondContact O-N 2.81Å; K242-R245 PolarHBondContact O-N 2.75Å; R245-R247 PolarHBondContact O-N 2.87Å; R245-E248 PolarHBondContact O-N 3.1Å
246A79.1Confident82.6Confident54 Ų5459.6 Ų59.645%0.44628%0.281SS..Hα-helixtrans-62.2-27.1177.100000113.1K242 V244K242-A246 WeakPolarHBondContact O-CB 3.17Å; K242-A246 PolarHBondContact O-N 3.25Å; V244-A246 VanDerWaalsContact C-N 3.29Å; V244-A246 PolarHBondContact O-N 2.75Å
247R79.5Confident82.9Confident16 Ų1654.9 Ų54.96%0.0626%0.261CS..Hα-helixtrans-108.6-11.6-177.9-65.1-165.4-174.1-122.3-6.7114R162 M164 D198 R243 V244 R245 T249R162-R247 WeakPolarHBondContact CD-O 3.39Å; R162-R247 PolarHBondContact NE-O 2.9Å; R162-R247 PolarHBondContact NH1-O 3.45Å; R162-R247 VanDerWaalsContact NH1-O 3.08Å; M164-R247 VanDerWaalsContact CE-C 3.48Å; M164-R247 HydrophobicContact CE-CB 3.7Å; M164-R247 WeakPolarHBondContact CE-O 3.49Å; D198-R247 WeakPolarHBondContact OD1-CD 3.4Å; D198-R247 IonicContact OD1-CZ 2.8Å; D198-R247 IonicContact OD1-NE 3.72Å; D198-R247 IonicContact OD1-NH1 2.61Å; D198-R247 PolarHBondContact OD1-NH1 3.06Å; R243-R247 PolarHBondContact O-N 2.8Å; V244-R247 CarbonylContact O-C 3.58Å; V244-R247 PolarHBondContact O-N 3.01Å; R245-R247 PolarHBondContact O-N 2.87Å; R247-T249 PolarHBondContact O-N 2.95Å
248E78.1Confident83.3Confident20 Ų2055 Ų559%0.09327%0.265CS..Hα-helixtrans-64.7-42.6-177.8-174.3-164150.200111.7L35 V67 K71 V244 R245L35-E248 HydrophobicContact CD2-CG 4.14Å; V67-E248 HydrophobicContact CG1-CG 3.89Å; K71-E248 WeakPolarHBondContact CD-OE1 3.37Å; K71-E248 WeakPolarHBondContact CE-OE1 3.43Å; K71-E248 IonicContact NZ-OE1 3.8Å; V244-E248 WeakPolarHBondContact O-CB 3.28Å; V244-E248 PolarHBondContact O-N 3.31Å; R245-E248 PolarHBondContact O-N 3.1Å
249T72.7Confident83.8Confident72 Ų7249.5 Ų49.544%0.44224%0.239SC..SBendtrans-107.1129.8-177.853.60000110.9R247R247-T249 PolarHBondContact O-N 2.95Å
250K72Confident84.4Confident54 Ų5449.1 Ų49.124%0.23524%0.239CC..  trans-73.3150.4169.9-165.1170-173.61550110.6H160 E222 R252H160-K250 VanDerWaalsContact CE1-CD 3.42Å; H160-K250 WeakPolarHBondContact CE1-CD 3.48Å; E222-K250 IonicContact OE1-NZ 3.72Å; E222-K250 PolarHBondContact OE1-NZ 3.39Å; E222-K250 WeakPolarHBondContact OE2-CE 3.21Å; E222-K250 IonicContact OE2-NZ 2.68Å; E222-K250 PolarHBondContact OE2-NZ 3.13Å; K250-R252 PolarHBondContact O-N 3.45Å; K250-R252 VanDerWaalsContact O-N 3.16Å
251K78.8Confident84.7Confident103 Ų10351 Ų5145%0.44825%0.249SC..  trans-56.1115.6169.3-58.3178.6-173.4-1780109.4D223 Y272D223-K251 IonicContact OD2-NZ 3.54Å; D223-K251 PolarHBondContact OD2-NZ 3.04Å; K251-Y272 HydrophobicContact CB-CD1 4.48Å; K251-Y272 HydrophobicContact CB-CE1 3.94Å
252R79.5Confident84.8Confident131 Ų13150 Ų5049%0.49425%0.251SS..  trans-109.9112.2177.3-68.8179.7-174.6164.81.8109.4D33 K250 Y272D33-R252 IonicContact OD2-CZ 2.76Å; D33-R252 IonicContact OD2-NE 2.69Å; D33-R252 IonicContact OD2-NH2 3.52Å; D33-R252 PolarHBondContact OD2-NH2 3.32Å; K250-R252 PolarHBondContact O-N 3.45Å; K250-R252 VanDerWaalsContact O-N 3.16Å; R252-Y272 WeakPolarHBondContact O-CD1 3.42Å
253A85.4Confident84.8Confident26 Ų2656.5 Ų56.522%0.21528%0.283CS..EExtended strand (participates in β ladder)trans-75.3124.4175.200000110.3A255 V271 Y272A253-A255 VanDerWaalsContact C-N 3.33Å; A253-V271 CarbonylContact C-O 3.6Å; A253-V271 VanDerWaalsContact CA-O 3.31Å; A253-V271 WeakPolarHBondContact CA-O 3.35Å; A253-Y272 HydrophobicContact CB-CD1 4.41Å; A253-Y272 HydrophobicContact CB-CE1 3.89Å
254L85.5Confident84.8Confident39 Ų3959.5 Ų59.520%0.20432%0.319CS..EExtended strand (participates in β ladder)trans-61.2-43.8170.3-172.180.4000110.4Y27 V271Y27-L254 VanDerWaalsContact CE1-O 3.31Å; Y27-L254 WeakPolarHBondContact CE1-O 3.35Å; Y27-L254 HydrophobicContact CE2-CD1 3.89Å; Y27-L254 VanDerWaalsContact CZ-O 3.27Å; Y27-L254 WeakPolarHBondContact OH-CA 3.47Å; Y27-L254 WeakPolarHBondContact OH-CD1 3.4Å; Y27-L254 VanDerWaalsContact OH-CG 3.24Å; Y27-L254 WeakPolarHBondContact OH-CG 3.44Å; Y27-L254 PolarHBondContact OH-O 2.8Å; L254-V271 HydrophobicContact CB-CG1 4.38Å; L254-V271 WeakPolarHBondContact CB-O 3.46Å; L254-V271 HydrophobicContact CD2-CG1 4.24Å; L254-V271 PolarHBondContact N-O 3.41Å
255A87.6Confident85Confident22 Ų2263.4 Ų63.418%0.18234%0.339CS..EExtended strand (participates in β ladder)trans-152.4151.9177.400000109.9A253 L257 V271A253-A255 VanDerWaalsContact C-N 3.33Å; A255-L257 HydrophobicContact CB-CD2 4.32Å; A255-L257 HydrophobicContact CB-CG 4.16Å; A255-V271 HydrophobicContact CB-CB 4.39Å; A255-V271 HydrophobicContact CB-CG2 4.36Å; A255-V271 PolarHBondContact O-N 3.49Å
256R90.8Very high85.4Confident148 Ų14861.3 Ų61.356%0.55834%0.337SS*.EExtended strand (participates in β ladder)trans-105.6121164.7-66.8-173.4176.7854.2107.6E369R256-E369 IonicContact CZ-OE2 2.64Å; R256-E369 IonicContact NE-OE2 3.2Å; R256-E369 PolarHBondContact NE-OE2 3.08Å; R256-E369 IonicContact NH2-OE2 2.9Å
257L92.5Very high86.1Confident14 Ų1459 Ų597%0.07332%0.317CS..EExtended strand (participates in β ladder)trans-126.2154.8-174-62.9-179.3000110.3A255 V269 V271 P341 L343 F400A255-L257 HydrophobicContact CB-CD2 4.32Å; A255-L257 HydrophobicContact CB-CG 4.16Å; L257-V269 HydrophobicContact CB-CG2 4.4Å; L257-V269 PolarHBondContact N-O 3.4Å; L257-V269 WeakPolarHBondContact O-CG2 3.48Å; L257-V269 PolarHBondContact O-N 3.2Å; L257-V271 HydrophobicContact CD1-CG2 3.74Å; L257-V271 HydrophobicContact CG-CG2 4.09Å; L257-P341 HydrophobicContact CD2-CB 4.21Å; L257-L343 HydrophobicContact CD1-CG 4.48Å; L257-F400 HydrophobicContact CD1-CD1 3.83Å; L257-F400 HydrophobicContact CD1-CE1 3.99Å; L257-F400 HydrophobicContact CD1-CG 4.48Å
258S93.8Very high86.9Confident42 Ų4258.6 Ų58.629%0.29432%0.317SS..EExtended strand (participates in β ladder)trans-88.8125167.6178.40000109.7N266 G342 L343S258-N266 WeakPolarHBondContact OG-CB 3.41Å; S258-G342 WeakPolarHBondContact O-CA 3.33Å; S258-L343 PolarHBondContact O-N 3.02Å
259L95.4Very high87.7Confident4 Ų457.7 Ų57.72%0.02131%0.313CS..EExtended strand (participates in β ladder)trans-91.3104.3166.1174.265.7000109.1L261 N266 V267 V269 L343 L411L259-L261 HydrophobicContact CG-CD1 4.35Å; L259-N266 WeakPolarHBondContact O-CA 3.4Å; L259-V267 HydrophobicContact CB-CB 4.24Å; L259-V267 PolarHBondContact N-O 2.98Å; L259-V267 PolarHBondContact O-N 3.37Å; L259-V269 HydrophobicContact CB-CG1 4.2Å; L259-V269 HydrophobicContact CB-CG2 4.19Å; L259-V269 HydrophobicContact CD2-CG1 4.5Å; L259-L343 CarbonylContact C-O 3.23Å; L259-L343 WeakPolarHBondContact CA-O 3.06Å; L259-L343 HydrophobicContact CB-CB 4.32Å; L259-L343 HydrophobicContact CD1-CB 3.55Å; L259-L343 HydrophobicContact CD1-CD1 4.42Å; L259-L411 HydrophobicContact CD1-CD1 4.16Å
260T94.9Very high88.7Confident33 Ų3354.3 Ų54.320%0.20229%0.292CS..EExtended strand (participates in β ladder)trans-90.9117.1179.5-57.30000110G262 N266 L343 F344 L345T260-G262 WeakPolarHBondContact CG2-O 3.36Å; T260-N266 WeakPolarHBondContact CA-OD1 3.46Å; T260-N266 WeakPolarHBondContact CB-OD1 3.47Å; T260-N266 WeakPolarHBondContact CG2-OD1 3.36Å; T260-N266 PolarHBondContact OG1-OD1 2.9Å; T260-L343 PolarHBondContact N-O 2.93Å; T260-F344 HydrophobicContact CG2-CD2 4.02Å; T260-F344 HydrophobicContact CG2-CE2 4.14Å; T260-L345 WeakPolarHBondContact O-CB 3.39Å; T260-L345 PolarHBondContact O-N 3.48Å
261L92.3Very high89.7Confident40 Ų4051.8 Ų51.821%0.20928%0.281CS..EExtended strand (participates in β ladder)trans-91.3-22.2177-68.395000112.8L259 L265 V267 L345 L379L259-L261 HydrophobicContact CG-CD1 4.35Å; L261-L265 HydrophobicContact CB-CD2 3.89Å; L261-L265 HydrophobicContact CB-CG 4.21Å; L261-L265 HydrophobicContact CD1-CG 4.37Å; L261-L265 PolarHBondContact N-O 3.01Å; L261-V267 HydrophobicContact CD1-CB 4.44Å; L261-V267 HydrophobicContact CD1-CG2 3.64Å; L261-L345 HydrophobicContact CB-CD2 4.17Å; L261-L345 HydrophobicContact CD2-CD2 4.12Å; L261-L345 HydrophobicContact CG-CD2 4.1Å; L261-L379 HydrophobicContact CD1-CD2 4.23Å
262G87.6Confident90.3Very high27 Ų2748.7 Ų48.728%0.27827%0.267SS..EExtended strand (participates in β ladder)trans178.1-177.5-17800000110.8T260 G264 L265T260-G262 WeakPolarHBondContact CG2-O 3.36Å; G262-G264 PolarHBondContact O-N 3.39Å; G262-L265 PolarHBondContact O-N 3.16Å; G262-L265 VanDerWaalsContact O-N 3.14Å
263E83.1Confident90.8Very high207 Ų20744.5 Ų44.597%0.96726%0.261SS*.THydrogen-bonded Turntrans-59.4119.8178.9-67.7-175.7178.200111L265E263-L265 VanDerWaalsContact C-N 3.27Å; E263-L265 PolarHBondContact O-N 3.48Å
264G83.1Confident90.9Very high80 Ų8047.6 Ų47.683%0.82528%0.277SS*.THydrogen-bonded Turntrans78.1-3.8-179.800000116.1G262G262-G264 PolarHBondContact O-N 3.39Å
265L90.5Very high90.9Very high82 Ų8249 Ų4943%0.42929%0.294SS..EExtended strand (participates in β ladder)trans-108.797.2-179.5-169.763.7000111.5L261 G262 E263 L379L261-L265 HydrophobicContact CB-CD2 3.89Å; L261-L265 HydrophobicContact CB-CG 4.21Å; L261-L265 HydrophobicContact CD1-CG 4.37Å; L261-L265 PolarHBondContact N-O 3.01Å; G262-L265 PolarHBondContact O-N 3.16Å; G262-L265 VanDerWaalsContact O-N 3.14Å; E263-L265 VanDerWaalsContact C-N 3.27Å; E263-L265 PolarHBondContact O-N 3.48Å; L265-L379 HydrophobicContact CD1-CD2 3.75Å; L265-L379 HydrophobicContact CD2-CD2 4.18Å; L265-L379 HydrophobicContact CG-CD2 4.04Å
266N91.3Very high90.7Very high74 Ų7451.6 Ų51.640%0.39631%0.308SS..EExtended strand (participates in β ladder)trans-120.3134.9-178.1-66.2-41.1000111S258 L259 T260S258-N266 WeakPolarHBondContact OG-CB 3.41Å; L259-N266 WeakPolarHBondContact O-CA 3.4Å; T260-N266 WeakPolarHBondContact CA-OD1 3.46Å; T260-N266 WeakPolarHBondContact CB-OD1 3.47Å; T260-N266 WeakPolarHBondContact CG2-OD1 3.36Å; T260-N266 PolarHBondContact OG1-OD1 2.9Å
267V94.6Very high90.5Very high4 Ų448.5 Ų48.52%0.02431%0.308CS..EExtended strand (participates in β ladder)trans-113.7126.7174.1177.20000108.1L259 L261 V269 L379 F380L259-V267 HydrophobicContact CB-CB 4.24Å; L259-V267 PolarHBondContact N-O 2.98Å; L259-V267 PolarHBondContact O-N 3.37Å; L261-V267 HydrophobicContact CD1-CB 4.44Å; L261-V267 HydrophobicContact CD1-CG2 3.64Å; V267-V269 HydrophobicContact CG1-CG1 3.96Å; V267-L379 HydrophobicContact CG2-CB 4.22Å; V267-L379 HydrophobicContact CG2-CD2 3.46Å; V267-L379 VanDerWaalsContact CG2-CD2 3.46Å; V267-L379 HydrophobicContact CG2-CG 3.9Å; V267-F380 HydrophobicContact CG1-CB 4.39Å
268A94.9Very high90.1Very high9 Ų950.7 Ų50.77%0.07433%0.329CS..EExtended strand (participates in β ladder)trans-76.3128.917300000109.7E369 E372 V373 S376A268-E369 HydrophobicContact CB-CB 4.1Å; A268-E369 PolarHBondContact O-N 2.96Å; A268-E372 HydrophobicContact CB-CB 3.71Å; A268-V373 HydrophobicContact CB-CB 3.84Å; A268-V373 HydrophobicContact CB-CG2 3.85Å; A268-S376 PolarHBondContact N-OG 3.02Å; A268-S376 VanDerWaalsContact N-OG 3.09Å
269V94.9Very high89.7Confident1 Ų153.8 Ų53.81%0.00633%0.334CS..EExtended strand (participates in β ladder)trans-132.7138.8178.6-620000111.4L257 L259 V267 L343 I366 Y367 F380L257-V269 HydrophobicContact CB-CG2 4.4Å; L257-V269 PolarHBondContact N-O 3.4Å; L257-V269 WeakPolarHBondContact O-CG2 3.48Å; L257-V269 PolarHBondContact O-N 3.2Å; L259-V269 HydrophobicContact CB-CG1 4.2Å; L259-V269 HydrophobicContact CB-CG2 4.19Å; L259-V269 HydrophobicContact CD2-CG1 4.5Å; V267-V269 HydrophobicContact CG1-CG1 3.96Å; V269-L343 HydrophobicContact CG2-CD1 4.01Å; V269-I366 HydrophobicContact CB-CB 4.45Å; V269-Y367 CarbonylContact C-O 3.49Å; V269-Y367 WeakPolarHBondContact CA-O 3.42Å; V269-F380 HydrophobicContact CG1-CD2 4.03Å; V269-F380 HydrophobicContact CG1-CE2 4.08Å
270G93.9Very high89.3Confident0 Ų059.8 Ų59.80%036%0.36CS..EExtended strand (participates in β ladder)trans-89.7134.2168.900000108.7Y272 I366 Y367G270-Y272 VanDerWaalsContact C-CE2 3.49Å; G270-Y272 WeakPolarHBondContact O-CD2 3.33Å; G270-Y272 WeakPolarHBondContact O-CE2 3.24Å; G270-I366 VanDerWaalsContact O-CA 3.28Å; G270-I366 WeakPolarHBondContact O-CA 3.25Å; G270-Y367 PolarHBondContact N-O 2.91Å; G270-Y367 PolarHBondContact O-N 3.5Å
271V93.1Very high88.9Confident1 Ų161.3 Ų61.31%0.00637%0.37CS..EExtended strand (participates in β ladder)trans-97.9128.2173.6-177.50000107.9A253 L254 A255 L257 V364 F365 I366 F400A253-V271 CarbonylContact C-O 3.6Å; A253-V271 VanDerWaalsContact CA-O 3.31Å; A253-V271 WeakPolarHBondContact CA-O 3.35Å; L254-V271 HydrophobicContact CB-CG1 4.38Å; L254-V271 WeakPolarHBondContact CB-O 3.46Å; L254-V271 HydrophobicContact CD2-CG1 4.24Å; L254-V271 PolarHBondContact N-O 3.41Å; A255-V271 HydrophobicContact CB-CB 4.39Å; A255-V271 HydrophobicContact CB-CG2 4.36Å; A255-V271 PolarHBondContact O-N 3.49Å; L257-V271 HydrophobicContact CD1-CG2 3.74Å; L257-V271 HydrophobicContact CG-CG2 4.09Å; V271-V364 HydrophobicContact CG1-CB 3.84Å; V271-V364 HydrophobicContact CG1-CG1 4.41Å; V271-V364 HydrophobicContact CG1-CG2 3.63Å; V271-F365 CarbonylContact C-O 2.93Å; V271-F365 WeakPolarHBondContact CA-O 2.89Å; V271-I366 HydrophobicContact CG2-CG2 4.06Å; V271-F400 HydrophobicContact CB-CE1 4.44Å; V271-F400 HydrophobicContact CG1-CE1 3.78Å; V271-F400 HydrophobicContact CG2-CE1 3.99Å
272Y91.4Very high88.6Confident39 Ų3963.8 Ų63.815%0.15340%0.396CS..EExtended strand (participates in β ladder)trans-123.4132.9-177.2-62-90.7000109.8K251 R252 A253 G270 F365 E369K251-Y272 HydrophobicContact CB-CD1 4.48Å; K251-Y272 HydrophobicContact CB-CE1 3.94Å; R252-Y272 WeakPolarHBondContact O-CD1 3.42Å; A253-Y272 HydrophobicContact CB-CD1 4.41Å; A253-Y272 HydrophobicContact CB-CE1 3.89Å; G270-Y272 VanDerWaalsContact C-CE2 3.49Å; G270-Y272 WeakPolarHBondContact O-CD2 3.33Å; G270-Y272 WeakPolarHBondContact O-CE2 3.24Å; Y272-F365 PolarHBondContact N-O 3.4Å; Y272-F365 PolarHBondContact O-N 2.67Å; Y272-E369 PolarHBondContact OH-OE1 2.83Å
273A90.7Very high88.6Confident43 Ų4368 Ų6836%0.35542%0.422SS..  trans-87.1109.3169.800000108.5V276A273-V276 HydrophobicContact CB-CG2 3.7Å
274T86.6Confident88.9Confident91 Ų9163 Ų6356%0.55841%0.406SS*.SBendtrans-84.5-22.8-17950.20000112.8F365T274-F365 HydrophobicContact CG2-CB 3.59Å; T274-F365 HydrophobicContact CG2-CG 4.24Å
275A85.4Confident89.4Confident69 Ų6968 Ų6857%0.5740%0.399SS*.  trans-135.7122.9173.600000109.5
276V85Confident89.6Confident76 Ų7668.4 Ų68.446%0.46140%0.401SS..  trans-124.2134.2178.7178.20000107.7L22 A273 A278L22-V276 WeakPolarHBondContact O-CG1 3.45Å; A273-V276 HydrophobicContact CB-CG2 3.7Å; V276-A278 PolarHBondContact O-N 3.02Å; V276-A278 VanDerWaalsContact O-N 3.11Å
277S85.1Confident89.8Confident82 Ų8270.4 Ų70.457%0.57340%0.404SS*.  trans-67.7112.6177.2-174.40000109.4R279S277-R279 PolarHBondContact O-N 3.47Å
278A85.3Confident89.8Confident61 Ų6181.1 Ų81.150%0.50444%0.444SS..  trans-66.2123.2171.800000109.6V276 L481V276-A278 PolarHBondContact O-N 3.02Å; V276-A278 VanDerWaalsContact O-N 3.11Å; A278-L481 HydrophobicContact CB-CD1 3.55Å
279R85.3Confident89.9Confident107 Ų10787.9 Ų87.940%0.40447%0.474SS..  trans-110.1154.1-179.4-61.5-175.4179.6-151-1.5110.3E19 S277E19-R279 PolarHBondContact O-NH2 3.44Å; E19-R279 VanDerWaalsContact O-NH2 3.14Å; E19-R279 IonicContact OE2-CZ 3.88Å; E19-R279 IonicContact OE2-NH1 3.69Å; E19-R279 PolarHBondContact OE2-NH1 2.8Å; E19-R279 IonicContact OE2-NH2 3.56Å; S277-R279 PolarHBondContact O-N 3.47Å
280K87.2Confident89.9Confident130 Ų13091.2 Ų91.257%0.56550%0.495SS*.PPolyproline II helixtrans-61.3130.3170.2-177-180177177.80108.8L481 H484K280-L481 HydrophobicContact CB-CD2 4.24Å; K280-H484 VanDerWaalsContact CE-CE1 3.44Å; K280-H484 WeakPolarHBondContact CE-CE1 3.24Å; K280-H484 WeakPolarHBondContact CE-ND1 3.41Å
281P85.8Confident89.8Confident64 Ų6496.6 Ų96.642%0.41652%0.523SS..PPolyproline II helixtrans-56140.7176.4-25.234000111.9F485P281-F485 HydrophobicContact CG-CE1 4.39Å; P281-F485 HydrophobicContact CG-CZ 3.77Å
282A85.7Confident89.8Confident92 Ų92102.6 Ų102.676%0.7655%0.551SS**PPolyproline II helixtrans-66.2144.8174.800000110.6
283S87.9Confident89.9Confident117 Ų117105.6 Ų105.682%0.81858%0.576SS**PPolyproline II helixtrans-66.6134.5176.658.10000111.2
284V90.2Very high90Very high102 Ų102107.2 Ų107.262%0.61858%0.581SS**PPolyproline II helixtrans-92.3131.9171.8-176.90000109.2L286 P293V284-L286 HydrophobicContact CG1-CD2 4.06Å; V284-P293 HydrophobicContact CG1-CB 4.08Å
285R92.4Very high90.2Very high183 Ų183111.6 Ų111.669%0.69159%0.587SS**PPolyproline II helixtrans-76128.4175.4-64.5-177-177.1178.91.7109.5V294R285-V294 HydrophobicContact CB-CB 4.38Å; R285-V294 PolarHBondContact O-N 3.41Å
286L94.7Very high90.4Very high91 Ų91112.1 Ų112.148%0.47659%0.587SS.*BIsolated β-bridgetrans-116.3152.5-179-53.9-178.7000111.3V284 N291 E292 P293V284-L286 HydrophobicContact CG1-CD2 4.06Å; L286-N291 HydrophobicContact CD1-CB 4.47Å; L286-E292 CarbonylContact C-O 3.59Å; L286-E292 WeakPolarHBondContact CA-O 3.46Å; L286-P293 HydrophobicContact CD2-CB 4.41Å; L286-P293 HydrophobicContact CD2-CG 4.2Å
287Y95.8Very high90.8Very high117 Ų117115.2 Ų115.246%0.45959%0.594SS.*  trans-76.3131.1169.3-174.3-107000109.9E289 T290 N291 E292Y287-E289 VanDerWaalsContact C-N 3.32Å; Y287-E289 HydrophobicContact CD1-CB 4.15Å; Y287-E289 HydrophobicContact CE1-CB 3.68Å; Y287-E289 HydrophobicContact CE1-CG 3.94Å; Y287-E289 WeakPolarHBondContact CE1-OE2 3.35Å; Y287-E289 PolarHBondContact O-N 3.15Å; Y287-E289 PolarHBondContact OH-OE2 2.86Å; Y287-T290 HydrophobicContact CD1-CG2 3.92Å; Y287-T290 WeakPolarHBondContact CD1-OG1 3.44Å; Y287-T290 HydrophobicContact CE1-CG2 4.22Å; Y287-T290 PolarHBondContact O-N 2.71Å; Y287-N291 VanDerWaalsContact O-CA 3.24Å; Y287-N291 WeakPolarHBondContact O-CA 3.42Å; Y287-N291 PolarHBondContact O-N 2.92Å; Y287-E292 PolarHBondContact N-O 3.13Å
288R95.3Very high91.1Very high229 Ų229115 Ų11586%0.86459%0.59SS**THydrogen-bonded Turntrans-57.9-38.4-169.2178.2-177.7-72.8-160.1-2.3114
289E96Very high91.4Very high151 Ų151119.9 Ų119.971%0.70660%0.595SS**THydrogen-bonded Turntrans-89.9-30.1-171-53.2172.215200112.5Y287Y287-E289 VanDerWaalsContact C-N 3.32Å; Y287-E289 HydrophobicContact CD1-CB 4.15Å; Y287-E289 HydrophobicContact CE1-CB 3.68Å; Y287-E289 HydrophobicContact CE1-CG 3.94Å; Y287-E289 WeakPolarHBondContact CE1-OE2 3.35Å; Y287-E289 PolarHBondContact O-N 3.15Å; Y287-E289 PolarHBondContact OH-OE2 2.86Å
290T95.1Very high91.8Very high71 Ų71118 Ų11844%0.43660%0.596SS.*THydrogen-bonded Turntrans-109-12.4-174.765.90000113.4Y287 E292Y287-T290 HydrophobicContact CD1-CG2 3.92Å; Y287-T290 WeakPolarHBondContact CD1-OG1 3.44Å; Y287-T290 HydrophobicContact CE1-CG2 4.22Å; Y287-T290 PolarHBondContact O-N 2.71Å; T290-E292 PolarHBondContact O-N 2.99Å; T290-E292 VanDerWaalsContact O-N 3.17Å; T290-E292 WeakPolarHBondContact OG1-CB 3.46Å; T290-E292 WeakPolarHBondContact OG1-CG 3.38Å; T290-E292 PolarHBondContact OG1-N 2.91Å
291N92.2Very high92.1Very high112 Ų112117.9 Ų117.960%0.59960%0.595SS**  trans56.120.2-170.4-62.7-44.3000114.2L286 Y287L286-N291 HydrophobicContact CD1-CB 4.47Å; Y287-N291 VanDerWaalsContact O-CA 3.24Å; Y287-N291 WeakPolarHBondContact O-CA 3.42Å; Y287-N291 PolarHBondContact O-N 2.92Å
292E93.6Very high92.5Very high127 Ų127118.3 Ų118.359%0.59359%0.592SS**PPolyproline II helixtrans-78.7142.7178.2-70.1179.6163.900111.9L286 Y287 T290 V294L286-E292 CarbonylContact C-O 3.59Å; L286-E292 WeakPolarHBondContact CA-O 3.46Å; Y287-E292 PolarHBondContact N-O 3.13Å; T290-E292 PolarHBondContact O-N 2.99Å; T290-E292 VanDerWaalsContact O-N 3.17Å; T290-E292 WeakPolarHBondContact OG1-CB 3.46Å; T290-E292 WeakPolarHBondContact OG1-CG 3.38Å; T290-E292 PolarHBondContact OG1-N 2.91Å; E292-V294 PolarHBondContact O-N 3.01Å
293P91.9Very high92.9Very high103 Ų103120.1 Ų120.167%0.66959%0.594SS**BIsolated β-bridgetrans-60.2133.6176.9-25.134.7000113.9V284 L286V284-P293 HydrophobicContact CG1-CB 4.08Å; L286-P293 HydrophobicContact CD2-CB 4.41Å; L286-P293 HydrophobicContact CD2-CG 4.2Å
294V93.3Very high93.2Very high77 Ų77123.1 Ų123.147%0.46760%0.595SS.*PPolyproline II helixtrans-98.3129.2179.7-179.20000110.7R285 E292R285-V294 HydrophobicContact CB-CB 4.38Å; R285-V294 PolarHBondContact O-N 3.41Å; E292-V294 PolarHBondContact O-N 3.01Å
295R92.1Very high93.3Very high182 Ų182122.7 Ų122.769%0.68759%0.593SS**PPolyproline II helixtrans-83.1119.1175.3-172.1174.5178.8176.32.6111.2
296S89.6Confident93.3Very high81 Ų81116.8 Ų116.857%0.56659%0.588SS**PPolyproline II helixtrans-80.7138.1170.7-164.60000111.1
297K92.3Very high93.2Very high140 Ų140115.2 Ų115.261%0.60959%0.585SS**  trans-128.7113.1170.4-70.2-176.5-178.7176.20108.5
298T91.5Very high93.1Very high78 Ų78113 Ų11348%0.47958%0.581SS.*  trans-89.1132.3176-52.10000109.3
299R91.4Very high93Very high163 Ų163103.8 Ų103.862%0.61555%0.548SS*.  trans-136.8132.9178.2-72-179.3175.7-178.7-3.3108.9L308R299-L308 HydrophobicContact CB-CD1 3.77Å; R299-L308 HydrophobicContact CG-CD1 4.06Å
300T93.1Very high92.7Very high69 Ų6999.8 Ų99.842%0.42353%0.532SS..  trans-97.3131.5177.2-49.20000109L308 L309 I314T300-L308 WeakPolarHBondContact O-CD1 3.22Å; T300-L309 HydrophobicContact CG2-CD1 4.18Å; T300-L309 PolarHBondContact O-N 3.44Å; T300-I314 HydrophobicContact CG2-CD1 4.36Å
301F94.8Very high92.4Very high126 Ų12699.1 Ų99.155%0.55353%0.529SS*.BIsolated β-bridgetrans-130.9152.2-177.850.9-90.8000110.9S307F301-S307 CarbonylContact C-O 3.6Å; F301-S307 VanDerWaalsContact CA-O 3.22Å; F301-S307 WeakPolarHBondContact CA-O 3.26Å; F301-S307 WeakPolarHBondContact CB-O 3.38Å
302H94.3Very high92.2Very high73 Ų7398.4 Ų98.434%0.33853%0.532SS..  trans-75.1127.1174-178.1-100.8000110Q304 T305 G306 S307 L309H302-Q304 VanDerWaalsContact C-N 3.32Å; H302-Q304 PolarHBondContact O-N 3.12Å; H302-T305 WeakPolarHBondContact CB-OG1 3.41Å; H302-T305 PolarHBondContact ND1-N 3.43Å; H302-T305 PolarHBondContact ND1-OG1 2.91Å; H302-T305 PolarHBondContact O-N 3.42Å; H302-G306 WeakPolarHBondContact O-CA 3.43Å; H302-G306 PolarHBondContact O-N 2.97Å; H302-S307 PolarHBondContact N-O 3.45Å; H302-L309 HydrophobicContact CB-CD1 4.26Å; H302-L309 HydrophobicContact CB-CD2 4.04Å; H302-L309 HydrophobicContact CB-CG 4.12Å
303T94.5Very high92Very high131 Ų13197.8 Ų97.880%0.80453%0.529SS*.THydrogen-bonded Turntrans-62.9-33.2-168.5-45.40000113.8
304Q93.8Very high92Very high180 Ų18095.1 Ų95.184%0.84151%0.509SS*.THydrogen-bonded Turntrans-89-35.9-177-61.8-179.7-6.800113.4H302H302-Q304 VanDerWaalsContact C-N 3.32Å; H302-Q304 PolarHBondContact O-N 3.12Å
305T91.9Very high92Very high93 Ų9397.1 Ų97.157%0.57151%0.511SS*.THydrogen-bonded Turntrans-96.9-17.2-174.354.90000112.3H302 S307H302-T305 WeakPolarHBondContact CB-OG1 3.41Å; H302-T305 PolarHBondContact ND1-N 3.43Å; H302-T305 PolarHBondContact ND1-OG1 2.91Å; H302-T305 PolarHBondContact O-N 3.42Å; T305-S307 PolarHBondContact O-N 2.95Å; T305-S307 VanDerWaalsContact O-N 3.15Å; T305-S307 PolarHBondContact OG1-N 2.77Å; T305-S307 PolarHBondContact OG1-OG 3.11Å
306G92.1Very high92.1Very high58 Ų5891.9 Ų91.960%0.59849%0.494SS*.  trans66.66.2-172.800000113.9H302H302-G306 WeakPolarHBondContact O-CA 3.43Å; H302-G306 PolarHBondContact O-N 2.97Å
307S92.5Very high92.3Very high59 Ų5990.5 Ų90.541%0.41349%0.487SS..PPolyproline II helixtrans-73.4140.3180570000110.7F301 H302 T305 L309F301-S307 CarbonylContact C-O 3.6Å; F301-S307 VanDerWaalsContact CA-O 3.22Å; F301-S307 WeakPolarHBondContact CA-O 3.26Å; F301-S307 WeakPolarHBondContact CB-O 3.38Å; H302-S307 PolarHBondContact N-O 3.45Å; T305-S307 PolarHBondContact O-N 2.95Å; T305-S307 VanDerWaalsContact O-N 3.15Å; T305-S307 PolarHBondContact OG1-N 2.77Å; T305-S307 PolarHBondContact OG1-OG 3.11Å; S307-L309 PolarHBondContact O-N 3.39Å
308L93.6Very high92.4Very high71 Ų7188.5 Ų88.537%0.37248%0.48SS..BIsolated β-bridgetrans-63.1132.3172.9-176.773.9000109.6Y8 R299 T300Y8-L308 WeakPolarHBondContact OH-CG 3.41Å; R299-L308 HydrophobicContact CB-CD1 3.77Å; R299-L308 HydrophobicContact CG-CD1 4.06Å; T300-L308 WeakPolarHBondContact O-CD1 3.22Å
309L92.7Very high92.7Very high34 Ų3489.4 Ų89.418%0.17849%0.485CS..PPolyproline II helixtrans-94.3120.2-179.9-73.8173.1000111.2Y8 T300 H302 S307 E313 I314Y8-L309 PolarHBondContact OH-O 3.47Å; T300-L309 HydrophobicContact CG2-CD1 4.18Å; T300-L309 PolarHBondContact O-N 3.44Å; H302-L309 HydrophobicContact CB-CD1 4.26Å; H302-L309 HydrophobicContact CB-CD2 4.04Å; H302-L309 HydrophobicContact CB-CG 4.12Å; S307-L309 PolarHBondContact O-N 3.39Å; L309-E313 WeakPolarHBondContact CA-OE2 3.36Å; L309-E313 HydrophobicContact CD2-CB 4.14Å; L309-I314 HydrophobicContact CB-CD1 4.08Å; L309-I314 HydrophobicContact CB-CG1 4.15Å
310L90.4Very high92.9Very high68 Ų6888.7 Ų88.736%0.35648%0.483SS..PPolyproline II helixtrans-76.2154.5172.9-63.4175.2000110.9S312 E313L310-S312 PolarHBondContact O-N 2.95Å; L310-S312 VanDerWaalsContact O-N 3.09Å; L310-E313 HydrophobicContact CB-CG 4.27Å; L310-E313 PolarHBondContact N-OE2 2.85Å; L310-E313 WeakPolarHBondContact O-CB 3.41Å; L310-E313 PolarHBondContact O-N 3.12Å
311P88.4Confident92.9Very high57 Ų5789.1 Ų89.137%0.3750%0.501SS..G310 helixtrans-54.1-31.6176.3-27.234.6000114.2F7 E313 I314F7-P311 WeakPolarHBondContact O-CG 3.33Å; P311-E313 PolarHBondContact O-N 2.83Å; P311-I314 PolarHBondContact O-N 3.49Å
312S88.9Confident92.9Very high97 Ų9795.4 Ų95.468%0.67852%0.522SS*.G310 helixtrans-71.2-16.1176.455.10000114.3L310L310-S312 PolarHBondContact O-N 2.95Å; L310-S312 VanDerWaalsContact O-N 3.09Å
313E88.6Confident92.9Very high113 Ų113100 Ų10053%0.52854%0.541SS..G310 helixtrans-94.7-4.9178.1-59.8174.8143.600111.6L309 L310 P311L309-E313 WeakPolarHBondContact CA-OE2 3.36Å; L309-E313 HydrophobicContact CD2-CB 4.14Å; L310-E313 HydrophobicContact CB-CG 4.27Å; L310-E313 PolarHBondContact N-OE2 2.85Å; L310-E313 WeakPolarHBondContact O-CB 3.41Å; L310-E313 PolarHBondContact O-N 3.12Å; P311-E313 PolarHBondContact O-N 2.83Å
314I91.3Very high93Very high47 Ų47100.2 Ų100.224%0.24153%0.532CS..  trans-110.2123.2-176.5-58.7171.2000109.1T300 L309 P311T300-I314 HydrophobicContact CG2-CD1 4.36Å; L309-I314 HydrophobicContact CB-CD1 4.08Å; L309-I314 HydrophobicContact CB-CG1 4.15Å; P311-I314 PolarHBondContact O-N 3.49Å
315K94.1Very high93.2Very high119 Ų11995.4 Ų95.452%0.51751%0.512SS..  trans-107.4153.6171.2-55.1-165.4-174.5-152.90110.9V326 E328K315-V326 HydrophobicContact CB-CG1 3.67Å; K315-V326 HydrophobicContact CD-CG1 3.68Å; K315-V326 HydrophobicContact CG-CG1 4.32Å; K315-E328 WeakPolarHBondContact CD-OE1 3.34Å; K315-E328 WeakPolarHBondContact CE-OE1 3.34Å; K315-E328 IonicContact NZ-OE1 3.06Å; K315-E328 PolarHBondContact NZ-OE1 3.23Å
316K93.6Very high93.4Very high73 Ų7394.5 Ų94.532%0.31751%0.506SS..EExtended strand (participates in β ladder)trans-90.7141.9172.7-61.9-64179.71800109.2E11 V326 M327 V332E11-K316 WeakPolarHBondContact OE1-CE 3.44Å; E11-K316 IonicContact OE1-NZ 3Å; E11-K316 PolarHBondContact OE1-NZ 3.17Å; E11-K316 IonicContact OE2-NZ 2.64Å; E11-K316 PolarHBondContact OE2-NZ 3.48Å; K316-V326 CarbonylContact O-C 3.41Å; K316-V326 WeakPolarHBondContact O-CA 3.45Å; K316-M327 PolarHBondContact N-O 2.83Å; K316-M327 PolarHBondContact O-N 3.36Å; K316-V332 HydrophobicContact CB-CG2 4.2Å; K316-V332 HydrophobicContact CG-CG2 4.38Å
317A94.3Very high93.5Very high51 Ų5193.4 Ų93.442%0.42149%0.485SS..EExtended strand (participates in β ladder)trans-136.9140.2177.200000111.5Q324 I325 V326A317-Q324 HydrophobicContact CB-CG 4.16Å; A317-I325 CarbonylContact C-O 3.58Å; A317-I325 VanDerWaalsContact CA-O 3.24Å; A317-I325 WeakPolarHBondContact CA-O 3.15Å; A317-V326 HydrophobicContact CB-CG2 4.32Å
318Q95.2Very high93.5Very high99 Ų9993.8 Ų93.846%0.46348%0.481SS..EExtended strand (participates in β ladder)trans-125.7136.7168.7-67.5-173.9000109.4Y320 I325Q318-Y320 HydrophobicContact CB-CD2 4.33Å; Q318-Y320 HydrophobicContact CB-CE2 3.71Å; Q318-Y320 PolarHBondContact OE1-OH 2.66Å; Q318-I325 PolarHBondContact N-O 2.72Å; Q318-I325 PolarHBondContact O-N 3.26Å
319V96.5Very high93.3Very high97 Ų9795.4 Ų95.459%0.58849%0.485SS*.EExtended strand (participates in β ladder)trans-108.4119.8-178-176.90000109.2Q324V319-Q324 HydrophobicContact CG2-CB 4.36Å; V319-Q324 HydrophobicContact CG2-CG 4.19Å
320Y95.9Very high93.3Very high148 Ų14899.9 Ų99.958%0.5851%0.509SS*.EExtended strand (participates in β ladder)trans-116.8114.1174.3-67.7-87.8000109.1Q318 R322 K323 I325Q318-Y320 HydrophobicContact CB-CD2 4.33Å; Q318-Y320 HydrophobicContact CB-CE2 3.71Å; Q318-Y320 PolarHBondContact OE1-OH 2.66Å; Y320-R322 PolarHBondContact O-N 2.85Å; Y320-R322 VanDerWaalsContact O-N 3.14Å; Y320-K323 PolarHBondContact N-O 3.08Å; Y320-K323 PolarHBondContact O-N 3.47Å; Y320-K323 VanDerWaalsContact O-N 3.11Å; Y320-I325 HydrophobicContact CD2-CD1 3.9Å; Y320-I325 HydrophobicContact CE2-CD1 4.41Å
321G93.9Very high93.3Very high78 Ų78101.4 Ų101.480%0.80451%0.514SS*.THydrogen-bonded Turntrans61.4-113.5-172.500000111.4
322R93.6Very high93.4Very high258 Ų258100.3 Ų100.397%0.97451%0.506SS*.THydrogen-bonded Turntrans-112.415.4177.8-61.4-175.8-177.4179.80.7113.4Y320Y320-R322 PolarHBondContact O-N 2.85Å; Y320-R322 VanDerWaalsContact O-N 3.14Å
323K96Very high93.4Very high170 Ų17097.7 Ų97.774%0.73949%0.485SS*.EExtended strand (participates in β ladder)trans-113.3126.1178.5-68.4-173.7178.6-1770109.8Y320Y320-K323 PolarHBondContact N-O 3.08Å; Y320-K323 PolarHBondContact O-N 3.47Å; Y320-K323 VanDerWaalsContact O-N 3.11Å
324Q96.7Very high93.6Very high134 Ų13495.2 Ų95.263%0.62648%0.483SS*.EExtended strand (participates in β ladder)trans-91.9125.3172-17417712.600108.8A317 V319 V326A317-Q324 HydrophobicContact CB-CG 4.16Å; V319-Q324 HydrophobicContact CG2-CB 4.36Å; V319-Q324 HydrophobicContact CG2-CG 4.19Å; Q324-V326 HydrophobicContact CG-CG2 3.98Å
325I96.1Very high93.6Very high80 Ų8098.3 Ų98.341%0.4150%0.5SS..EExtended strand (participates in β ladder)trans-104.6115.4174.4-55.5175.7000106.2A317 Q318 Y320 M327A317-I325 CarbonylContact C-O 3.58Å; A317-I325 VanDerWaalsContact CA-O 3.24Å; A317-I325 WeakPolarHBondContact CA-O 3.15Å; Q318-I325 PolarHBondContact N-O 2.72Å; Q318-I325 PolarHBondContact O-N 3.26Å; Y320-I325 HydrophobicContact CD2-CD1 3.9Å; Y320-I325 HydrophobicContact CE2-CD1 4.41Å; I325-M327 HydrophobicContact CG2-CG 4.35Å
326V96Very high93.3Very high74 Ų7496.1 Ų96.145%0.44849%0.49SS..EExtended strand (participates in β ladder)trans-104.9133.9179.2-176.10000108.1K315 K316 A317 Q324K315-V326 HydrophobicContact CB-CG1 3.67Å; K315-V326 HydrophobicContact CD-CG1 3.68Å; K315-V326 HydrophobicContact CG-CG1 4.32Å; K316-V326 CarbonylContact O-C 3.41Å; K316-V326 WeakPolarHBondContact O-CA 3.45Å; A317-V326 HydrophobicContact CB-CG2 4.32Å; Q324-V326 HydrophobicContact CG-CG2 3.98Å
327M94.5Very high93.2Very high34 Ų3498.5 Ų98.517%0.16750%0.5CS..EExtended strand (participates in β ladder)trans-135145.8-179.9-66.1176.2-7000109.9K316 I325 E331 V332 I335K316-M327 PolarHBondContact N-O 2.83Å; K316-M327 PolarHBondContact O-N 3.36Å; I325-M327 HydrophobicContact CG2-CG 4.35Å; M327-E331 VanDerWaalsContact CA-OE2 3.28Å; M327-E331 WeakPolarHBondContact CA-OE2 3.32Å; M327-E331 HydrophobicContact CB-CB 4.31Å; M327-V332 HydrophobicContact CB-CG2 3.98Å; M327-V332 HydrophobicContact CE-CG2 4.14Å; M327-V332 HydrophobicContact SD-CG2 4.41Å; M327-I335 HydrophobicContact SD-CD1 3.76Å
328E93.4Very high93Very high68 Ų68101.8 Ų101.832%0.31851%0.505SS..  trans-70.9157.6165.7-59.4-60.116300110.5K315 D330 E331 V332K315-E328 WeakPolarHBondContact CD-OE1 3.34Å; K315-E328 WeakPolarHBondContact CE-OE1 3.34Å; K315-E328 IonicContact NZ-OE1 3.06Å; K315-E328 PolarHBondContact NZ-OE1 3.23Å; E328-D330 VanDerWaalsContact C-N 3.25Å; E328-D330 PolarHBondContact O-N 2.97Å; E328-E331 HydrophobicContact CB-CG 4.13Å; E328-E331 PolarHBondContact N-OE2 2.76Å; E328-E331 WeakPolarHBondContact O-CB 3.38Å; E328-E331 PolarHBondContact O-N 3.01Å; E328-E331 VanDerWaalsContact O-N 3.13Å; E328-V332 PolarHBondContact O-N 2.97Å; E328-V332 VanDerWaalsContact O-N 3.16Å
329K89.9Confident92.7Very high104 Ų104100.7 Ų100.745%0.45250%0.5SS..Hα-helixtrans-57.3-41.7176.4-175.2175.4178.6173.20111.9E331 V332 D333K329-E331 VanDerWaalsContact C-N 3.27Å; K329-E331 PolarHBondContact O-N 2.82Å; K329-V332 WeakPolarHBondContact O-CB 3.45Å; K329-V332 PolarHBondContact O-N 2.9Å; K329-D333 PolarHBondContact O-N 2.81Å
330D90.9Very high92.4Very high128 Ų128101.7 Ų101.768%0.68450%0.502SS*.Hα-helixtrans-64.8-32.1179.4-65.2-12.8000112.4E328 D333 A334E328-D330 VanDerWaalsContact C-N 3.25Å; E328-D330 PolarHBondContact O-N 2.97Å; D330-D333 PolarHBondContact O-N 2.87Å; D330-A334 VanDerWaalsContact O-CB 3.24Å; D330-A334 WeakPolarHBondContact O-CB 3.42Å; D330-A334 PolarHBondContact O-N 2.82Å
331E92.4Very high92.2Very high101 Ų10196.8 Ų96.847%0.47249%0.489SS..Hα-helixtrans-69.5-41.6175.3-66.4178.6133.900110.9M327 E328 K329 D333 A334 I335M327-E331 VanDerWaalsContact CA-OE2 3.28Å; M327-E331 WeakPolarHBondContact CA-OE2 3.32Å; M327-E331 HydrophobicContact CB-CB 4.31Å; E328-E331 HydrophobicContact CB-CG 4.13Å; E328-E331 PolarHBondContact N-OE2 2.76Å; E328-E331 WeakPolarHBondContact O-CB 3.38Å; E328-E331 PolarHBondContact O-N 3.01Å; E328-E331 VanDerWaalsContact O-N 3.13Å; K329-E331 VanDerWaalsContact C-N 3.27Å; K329-E331 PolarHBondContact O-N 2.82Å; E331-D333 VanDerWaalsContact C-N 3.31Å; E331-D333 PolarHBondContact O-N 3.47Å; E331-A334 PolarHBondContact O-N 3.49Å; E331-I335 WeakPolarHBondContact O-CD1 3.44Å; E331-I335 VanDerWaalsContact O-CG1 3.23Å; E331-I335 WeakPolarHBondContact O-CG1 3.37Å; E331-I335 PolarHBondContact O-N 3.29Å
332V90.3Very high92.2Very high33 Ų3393.7 Ų93.720%0.246%0.456CS..Hα-helixtrans-60.6-42.4174.7176.50000111K316 M327 E328 K329 K336K316-V332 HydrophobicContact CB-CG2 4.2Å; K316-V332 HydrophobicContact CG-CG2 4.38Å; M327-V332 HydrophobicContact CB-CG2 3.98Å; M327-V332 HydrophobicContact CE-CG2 4.14Å; M327-V332 HydrophobicContact SD-CG2 4.41Å; E328-V332 PolarHBondContact O-N 2.97Å; E328-V332 VanDerWaalsContact O-N 3.16Å; K329-V332 WeakPolarHBondContact O-CB 3.45Å; K329-V332 PolarHBondContact O-N 2.9Å; V332-K336 PolarHBondContact O-N 2.77Å
333D89.2Confident92.3Very high42 Ų4281.5 Ų81.523%0.22541%0.41CS..Hα-helixtrans-68.3-39.3176.7-78.4-8.2000112.4K329 D330 E331 I335 K336 K337 N403K329-D333 PolarHBondContact O-N 2.81Å; D330-D333 PolarHBondContact O-N 2.87Å; E331-D333 VanDerWaalsContact C-N 3.31Å; E331-D333 PolarHBondContact O-N 3.47Å; D333-I335 VanDerWaalsContact C-N 3.34Å; D333-I335 PolarHBondContact O-N 3.28Å; D333-K336 PolarHBondContact O-N 3Å; D333-K337 PolarHBondContact O-N 3.17Å; D333-N403 HydrophobicContact CB-CB 4.45Å
334A91.6Very high92.3Very high61 Ų6177.5 Ų77.550%0.50439%0.393SS..Hα-helixtrans-63.6-38.4177.300000112D330 E331 K336 K337D330-A334 VanDerWaalsContact O-CB 3.24Å; D330-A334 WeakPolarHBondContact O-CB 3.42Å; D330-A334 PolarHBondContact O-N 2.82Å; E331-A334 PolarHBondContact O-N 3.49Å; A334-K336 PolarHBondContact O-N 3.5Å; A334-K337 WeakPolarHBondContact O-CB 3.48Å; A334-K337 PolarHBondContact O-N 3.4Å; A334-K337 VanDerWaalsContact O-N 3.09Å
335I90.5Very high92.3Very high113 Ų11372.3 Ų72.358%0.57937%0.369SS*.Hα-helixtrans-62.8-32.2176.6-67.4160.7000111.4M327 E331 D333 K337M327-I335 HydrophobicContact SD-CD1 3.76Å; E331-I335 WeakPolarHBondContact O-CD1 3.44Å; E331-I335 VanDerWaalsContact O-CG1 3.23Å; E331-I335 WeakPolarHBondContact O-CG1 3.37Å; E331-I335 PolarHBondContact O-N 3.29Å; D333-I335 VanDerWaalsContact C-N 3.34Å; D333-I335 PolarHBondContact O-N 3.28Å; I335-K337 VanDerWaalsContact C-N 3.35Å
336K89Confident92.3Very high72 Ų7272.6 Ų72.631%0.31337%0.371SS..Hα-helixtrans-82-10.2177.1-63.2175.6-177.6173.80113.2E14 V332 D333 A334 F338 N403 Y404E14-K336 IonicContact OE1-NZ 2.73Å; V332-K336 PolarHBondContact O-N 2.77Å; D333-K336 PolarHBondContact O-N 3Å; A334-K336 PolarHBondContact O-N 3.5Å; K336-F338 WeakPolarHBondContact O-CD2 3.44Å; K336-N403 WeakPolarHBondContact CB-O 3.47Å; K336-N403 CarbonylContact O-C 3.58Å; K336-Y404 CarbonylContact O-C 3.47Å; K336-Y404 PolarHBondContact O-N 2.66Å
337K91.1Very high92.3Very high124 Ų12470.3 Ų70.354%0.53936%0.362SS..  trans-89.1110.8-175.2-173.6-177.5177.5-177.20111.7D333 A334 I335D333-K337 PolarHBondContact O-N 3.17Å; A334-K337 WeakPolarHBondContact O-CB 3.48Å; A334-K337 PolarHBondContact O-N 3.4Å; A334-K337 VanDerWaalsContact O-N 3.09Å; I335-K337 VanDerWaalsContact C-N 3.35Å
338F90.9Very high92.4Very high120 Ų12073.4 Ų73.453%0.52638%0.375SS..  trans-109.4-54.4176.2-72.1-102.6000112.9K336 P405 P406K336-F338 WeakPolarHBondContact O-CD2 3.44Å; F338-P405 HydrophobicContact CD2-CB 4.46Å; F338-P405 HydrophobicContact CE2-CB 4.33Å; F338-P406 HydrophobicContact CB-CG 4.13Å; F338-P406 HydrophobicContact CD1-CG 4.4Å; F338-P406 HydrophobicContact CG-CG 4.18Å
339H89.2Confident92.6Very high75 Ų7574.9 Ų74.935%0.34738%0.38SS..SBendtrans-139.3163.6-178.4-58.2-68.3000110.1R397 V399H339-R397 PolarHBondContact CD2-NE 3.47Å; H339-R397 PolarHBondContact CD2-NH1 3.26Å; H339-R397 PolarHBondContact CE1-NH1 2.93Å; H339-R397 VanDerWaalsContact CE1-NH1 3.29Å; H339-R397 VanDerWaalsContact NE2-CZ 3.27Å; H339-R397 PolarHBondContact NE2-NH1 2.92Å; H339-V399 HydrophobicContact CB-CG2 4.23Å
340D90.2Very high93Very high118 Ų11873.1 Ų73.163%0.63138%0.379SS*.  trans-71.3156.2172.3-68.2-43.6000111.5G342D340-G342 PolarHBondContact O-N 3.08Å
341P91.9Very high93.2Very high46 Ų4669 Ų6930%0.29936%0.357SS..SBendtrans-59.4131.6-179.7-24.235000112.8L257 V399 R402L257-P341 HydrophobicContact CD2-CB 4.21Å; P341-V399 CarbonylContact C-O 3.55Å; P341-V399 VanDerWaalsContact CA-O 3.24Å; P341-V399 WeakPolarHBondContact CA-O 3.4Å; P341-R402 HydrophobicContact CG-CG 3.75Å
342G93.1Very high93.3Very high12 Ų1272.1 Ų72.112%0.12437%0.371CS..EExtended strand (participates in β ladder)trans161.6174.2-177.800000113S258 D340 V399S258-G342 WeakPolarHBondContact O-CA 3.33Å; D340-G342 PolarHBondContact O-N 3.08Å; G342-V399 PolarHBondContact N-O 2.92Å; G342-V399 PolarHBondContact O-N 3.19Å
343L95.3Very high93.6Very high2 Ų277.8 Ų77.81%0.0139%0.393CS..EExtended strand (participates in β ladder)trans-108.6121.5170-67.3165.8000107.9L257 S258 L259 T260 V269 I366 R397 V409L257-L343 HydrophobicContact CD1-CG 4.48Å; S258-L343 PolarHBondContact O-N 3.02Å; L259-L343 CarbonylContact C-O 3.23Å; L259-L343 WeakPolarHBondContact CA-O 3.06Å; L259-L343 HydrophobicContact CB-CB 4.32Å; L259-L343 HydrophobicContact CD1-CB 3.55Å; L259-L343 HydrophobicContact CD1-CD1 4.42Å; T260-L343 PolarHBondContact N-O 2.93Å; V269-L343 HydrophobicContact CG2-CD1 4.01Å; L343-I366 HydrophobicContact CD1-CD1 4.31Å; L343-I366 HydrophobicContact CD1-CG2 4.34Å; L343-R397 WeakPolarHBondContact CA-O 3.28Å; L343-V409 HydrophobicContact CD2-CG2 4.1Å
344F95.7Very high93.8Very high87 Ų8777.7 Ų77.738%0.38239%0.393SS..EExtended strand (participates in β ladder)trans-109.9118.8177.4-175.6-91.9000109.7T260 I346 C396 R397T260-F344 HydrophobicContact CG2-CD2 4.02Å; T260-F344 HydrophobicContact CG2-CE2 4.14Å; F344-I346 PolarHBondContact O-N 3.14Å; F344-C396 CarbonylContact O-C 3.33Å; F344-C396 WeakPolarHBondContact O-CA 3.43Å; F344-C396 WeakPolarHBondContact O-CB 3.36Å; F344-R397 HydrophobicContact CB-CB 4.43Å; F344-R397 PolarHBondContact N-O 3.04Å; F344-R397 PolarHBondContact O-N 3.06Å
345L96.8Very high94Very high24 Ų2480 Ų8013%0.12639%0.391CS..EExtended strand (participates in β ladder)trans-68.4128.4178.2-178.664.3000110.5T260 L261 F348 A394T260-L345 WeakPolarHBondContact O-CB 3.39Å; T260-L345 PolarHBondContact O-N 3.48Å; L261-L345 HydrophobicContact CB-CD2 4.17Å; L261-L345 HydrophobicContact CD2-CD2 4.12Å; L261-L345 HydrophobicContact CG-CD2 4.1Å; L345-F348 HydrophobicContact CD1-CZ 4.34Å; L345-F348 HydrophobicContact CD2-CE2 4.1Å; L345-F348 HydrophobicContact CD2-CZ 4.01Å; L345-A394 HydrophobicContact CD1-CB 3.76Å
346I96.1Very high94.2Very high87 Ų8782.6 Ų82.645%0.44641%0.405SS..EExtended strand (participates in β ladder)trans-99.7-39.3175-56.9176.2000110.1F344 L395 R397 F408F344-I346 PolarHBondContact O-N 3.14Å; I346-L395 HydrophobicContact CB-CD2 4.43Å; I346-L395 HydrophobicContact CB-CG 4.33Å; I346-L395 WeakPolarHBondContact CB-O 3.42Å; I346-L395 HydrophobicContact CD1-CG 4.29Å; I346-L395 HydrophobicContact CG2-CD2 4.34Å; I346-L395 PolarHBondContact N-O 2.71Å; I346-R397 HydrophobicContact CD1-CB 4.19Å; I346-F408 HydrophobicContact CD1-CD1 3.57Å; I346-F408 HydrophobicContact CD1-CE1 3.34Å
347G96.2Very high94.3Very high25 Ų2586 Ų8626%0.25842%0.422SS..EExtended strand (participates in β ladder)trans164.1-164.9179.800000112L395G347-L395 PolarHBondContact N-O 2.8Å; G347-L395 PolarHBondContact O-N 2.69Å
348F97.6Very high94.5Very high99 Ų9982.4 Ų82.443%0.43441%0.407SS..EExtended strand (participates in β ladder)trans-118.7141.4-178.5-59.6-90.3000110.6L345 L383 V392 F393 A394L345-F348 HydrophobicContact CD1-CZ 4.34Å; L345-F348 HydrophobicContact CD2-CE2 4.1Å; L345-F348 HydrophobicContact CD2-CZ 4.01Å; F348-L383 HydrophobicContact CE1-CD1 3.73Å; F348-L383 HydrophobicContact CZ-CD1 3.66Å; F348-V392 HydrophobicContact CB-CB 4.37Å; F348-V392 HydrophobicContact CB-CG2 4.31Å; F348-V392 HydrophobicContact CD1-CG2 4.21Å; F348-F393 WeakPolarHBondContact CA-O 3.31Å; F348-A394 HydrophobicContact CD1-CB 3.94Å; F348-A394 HydrophobicContact CE1-CB 3.73Å
349K97.4Very high94.6Very high99 Ų9982.2 Ų82.243%0.4341%0.407SS..EExtended strand (participates in β ladder)trans-128.9148176.2-80-175.4177.2176.90110.8V392 F393 L395K349-V392 CarbonylContact O-C 3.52Å; K349-V392 VanDerWaalsContact O-CA 3.26Å; K349-V392 WeakPolarHBondContact O-CA 3.39Å; K349-V392 WeakPolarHBondContact O-CB 3.46Å; K349-F393 HydrophobicContact CB-CD1 4.27Å; K349-F393 HydrophobicContact CB-CE1 3.62Å; K349-F393 HydrophobicContact CB-CE2 3.92Å; K349-F393 HydrophobicContact CB-CZ 3.44Å; K349-F393 VanDerWaalsContact CB-CZ 3.44Å; K349-F393 HydrophobicContact CD-CE2 4.5Å; K349-F393 HydrophobicContact CD-CZ 4.05Å; K349-F393 HydrophobicContact CG-CZ 4.34Å; K349-F393 PolarHBondContact N-O 2.8Å; K349-F393 VanDerWaalsContact O-CD1 3.3Å; K349-F393 WeakPolarHBondContact O-CD1 3.41Å; K349-F393 PolarHBondContact O-N 3.48Å; K349-L395 HydrophobicContact CD-CD2 4.33Å
350P97.6Very high94.8Very high67 Ų6781.5 Ų81.544%0.43541%0.406SS..EExtended strand (participates in β ladder)trans-61.8144.3174.6-21.232.6000112.3E352 K353 F393P350-E352 PolarHBondContact O-N 3.09Å; P350-K353 PolarHBondContact O-N 3.02Å; P350-K353 VanDerWaalsContact O-N 3.1Å; P350-F393 WeakPolarHBondContact O-CE1 3.45Å
351M94.8Very high94.8Very high42 Ų4278.1 Ų78.121%0.20738%0.384CS..G310 helixtrans-56-32.8178.7-76.8-62-16500113.7K353 L354 N391 F393 V412 P413M351-K353 PolarHBondContact O-N 3.44Å; M351-K353 VanDerWaalsContact O-N 3.09Å; M351-L354 WeakPolarHBondContact O-CB 3.35Å; M351-L354 PolarHBondContact O-N 2.7Å; M351-N391 WeakPolarHBondContact CG-O 3.47Å; M351-N391 VanDerWaalsContact CG-OD1 3.24Å; M351-N391 WeakPolarHBondContact CG-OD1 3.3Å; M351-N391 PolarHBondContact N-O 3.11Å; M351-N391 VanDerWaalsContact N-O 3.09Å; M351-F393 HydrophobicContact CE-CB 4.23Å; M351-F393 HydrophobicContact SD-CB 3.99Å; M351-F393 HydrophobicContact SD-CD1 4.07Å; M351-V412 HydrophobicContact CE-CB 4.35Å; M351-V412 HydrophobicContact CE-CG1 3.72Å; M351-V412 HydrophobicContact SD-CG1 4.39Å; M351-V412 HydrophobicContact SD-CG2 4.48Å; M351-P413 VanDerWaalsContact CE-CD 3.46Å; M351-P413 HydrophobicContact CE-CG 3.62Å
352E95.6Very high94.8Very high167 Ų16778.9 Ų78.978%0.7839%0.389SS*.G310 helixtrans-59.3-23.5178.7-61.1175.8-176.400114.1P350 L354P350-E352 PolarHBondContact O-N 3.09Å; E352-L354 VanDerWaalsContact C-N 3.28Å
353K95.1Very high94.8Very high151 Ų15179.8 Ų79.866%0.65739%0.393SS*.G310 helixtrans-79.2-14.9177.8-63.2-61.6-175.3-174.40112.5P350 M351P350-K353 PolarHBondContact O-N 3.02Å; P350-K353 VanDerWaalsContact O-N 3.1Å; M351-K353 PolarHBondContact O-N 3.44Å; M351-K353 VanDerWaalsContact O-N 3.09Å
354L95Very high94.7Very high41 Ų4180.2 Ų80.222%0.21540%0.396CS..  trans-88.2114177.1-171.766.5000109.5M351 E352 F393 A410 V412 I433 L435M351-L354 WeakPolarHBondContact O-CB 3.35Å; M351-L354 PolarHBondContact O-N 2.7Å; E352-L354 VanDerWaalsContact C-N 3.28Å; L354-F393 HydrophobicContact CB-CD1 4.33Å; L354-F393 HydrophobicContact CB-CE1 3.92Å; L354-A410 HydrophobicContact CD1-CB 4.12Å; L354-A410 HydrophobicContact CD2-CB 4.47Å; L354-V412 HydrophobicContact CD2-CG2 3.51Å; L354-I433 HydrophobicContact CD2-CD1 4.1Å; L354-L435 HydrophobicContact CD1-CD2 3.64Å
355K94.8Very high94.8Very high108 Ų10876.6 Ų76.647%0.4738%0.38SS..  trans-99.1134.9-176.7-59.5-176.7-174.5175.30110.6H357 H358K355-H357 VanDerWaalsContact C-N 3.3Å; K355-H357 WeakPolarHBondContact CD-NE2 3.31Å; K355-H357 PolarHBondContact O-N 3.31Å; K355-H358 WeakPolarHBondContact O-CB 3.39Å; K355-H358 PolarHBondContact O-N 3.45Å; K355-H358 VanDerWaalsContact O-N 3.13Å
356L93.9Very high94.7Very high169 Ų16975.4 Ų75.489%0.88537%0.374SS*.G310 helixtrans-58.7-38.3179.6-68.4170.6000113.1H358 H359L356-H358 PolarHBondContact O-N 3.16Å; L356-H359 PolarHBondContact O-N 3.09Å
357H93Very high94.6Very high144 Ų14475 Ų7567%0.66737%0.367SS*.G310 helixtrans-76.30.5-179.458.6-99.7000114.4K355K355-H357 VanDerWaalsContact C-N 3.3Å; K355-H357 WeakPolarHBondContact CD-NE2 3.31Å; K355-H357 PolarHBondContact O-N 3.31Å
358H94.3Very high94.5Very high48 Ų4874.5 Ų74.522%0.22236%0.36CS..G310 helixtrans-8712.6171.4-69.5-179.3000112.5K355 L356 I360 P436K355-H358 WeakPolarHBondContact O-CB 3.39Å; K355-H358 PolarHBondContact O-N 3.45Å; K355-H358 VanDerWaalsContact O-N 3.13Å; L356-H358 PolarHBondContact O-N 3.16Å; H358-I360 PolarHBondContact O-N 3.35Å; H358-P436 HydrophobicContact CB-CG 3.92Å; H358-P436 WeakPolarHBondContact O-CD 3.4Å
359H93.8Very high94.1Very high115 Ų11571.1 Ų71.153%0.53235%0.345SS..  trans-64.7123.5175.3-177.481.6000111L356 R361L356-H359 PolarHBondContact O-N 3.09Å; H359-R361 PolarHBondContact CE1-O 2.84Å
360I92.1Very high93.7Very high60 Ų6070.2 Ų70.231%0.30834%0.342SS..  trans-111.3-31.7177.964.9173.2000113.5H358 P436H358-I360 PolarHBondContact O-N 3.35Å; I360-P436 HydrophobicContact CG2-CB 3.7Å; I360-P436 HydrophobicContact CG2-CG 4.3Å
361R90.3Very high93Very high48 Ų4870.9 Ų70.918%0.18136%0.362CS..SBendtrans-161.3161.7-176.874.5-172-178.9164.7-1.9110.7E21 H359 S363 Y434E21-R361 IonicContact OE2-NH1 2.93Å; H359-R361 PolarHBondContact CE1-O 2.84Å; R361-S363 PolarHBondContact O-N 2.87Å; R361-Y434 HydrophobicContact CG-CD2 3.34Å; R361-Y434 HydrophobicContact CG-CE2 3.94Å; R361-Y434 HydrophobicContact CG-CG 3.81Å; R361-Y434 VanDerWaalsContact NE-CD1 3.34Å; R361-Y434 VanDerWaalsContact NE-CD2 3.29Å
362P91.7Very high92.6Very high61 Ų6174.9 Ų74.940%0.39638%0.38SS..  trans-51.2138.1179.4-27.436.1000112.4L22 Y434L22-P362 HydrophobicContact CD2-CG 3.83Å; P362-Y434 WeakPolarHBondContact O-CD2 2.91Å; P362-Y434 VanDerWaalsContact O-CE2 3.24Å; P362-Y434 WeakPolarHBondContact O-CE2 3.3Å
363S93.3Very high92.3Very high31 Ų3170 Ų7022%0.21736%0.362CS..  trans-74.8149.8175.5-57.50000110.7R361 V432R361-S363 PolarHBondContact O-N 2.87Å; S363-V432 WeakPolarHBondContact CA-O 3.31Å; S363-V432 WeakPolarHBondContact CB-O 3.44Å
364V94.6Very high92.2Very high12 Ų1271.9 Ų71.97%0.07337%0.37CS..EExtended strand (participates in β ladder)trans-108.8161.7169.1-60.60000109.3V271 F400 V432 Y434V271-V364 HydrophobicContact CG1-CB 3.84Å; V271-V364 HydrophobicContact CG1-CG1 4.41Å; V271-V364 HydrophobicContact CG1-CG2 3.63Å; V364-F400 HydrophobicContact CG2-CE1 4.42Å; V364-F400 HydrophobicContact CG2-CZ 4.19Å; V364-V432 HydrophobicContact CG2-CB 3.54Å; V364-V432 HydrophobicContact CG2-CG1 4.05Å; V364-V432 HydrophobicContact CG2-CG2 3.81Å; V364-V432 PolarHBondContact N-O 2.92Å; V364-V432 WeakPolarHBondContact O-CB 3.17Å; V364-V432 PolarHBondContact O-N 2.88Å; V364-Y434 WeakPolarHBondContact CG2-OH 3.34Å
365F95.8Very high91.9Very high10 Ų1071.8 Ų71.84%0.04438%0.378CS..EExtended strand (participates in β ladder)trans-110.3141.3-179.8-175.7-105.3000110V271 Y272 T274 Y367 P427 P428 F430V271-F365 CarbonylContact C-O 2.93Å; V271-F365 WeakPolarHBondContact CA-O 2.89Å; Y272-F365 PolarHBondContact N-O 3.4Å; Y272-F365 PolarHBondContact O-N 2.67Å; T274-F365 HydrophobicContact CG2-CB 3.59Å; T274-F365 HydrophobicContact CG2-CG 4.24Å; F365-Y367 HydrophobicContact CE1-CD2 4.09Å; F365-P427 HydrophobicContact CE1-CB 4.15Å; F365-P427 HydrophobicContact CE1-CG 4.09Å; F365-P427 HydrophobicContact CE2-CG 4.07Å; F365-P427 HydrophobicContact CZ-CB 3.85Å; F365-P427 HydrophobicContact CZ-CG 3.76Å; F365-P428 WeakPolarHBondContact CZ-O 3.47Å; F365-F430 WeakPolarHBondContact CD2-O 3.19Å
366I95.4Very high91.8Very high0 Ų066.7 Ų66.70%036%0.357CS..EExtended strand (participates in β ladder)trans-115.8141.2172.957.6167.7000111.7V269 G270 V271 L343 F380 L411 F430 V432V269-I366 HydrophobicContact CB-CB 4.45Å; G270-I366 VanDerWaalsContact O-CA 3.28Å; G270-I366 WeakPolarHBondContact O-CA 3.25Å; V271-I366 HydrophobicContact CG2-CG2 4.06Å; L343-I366 HydrophobicContact CD1-CD1 4.31Å; L343-I366 HydrophobicContact CD1-CG2 4.34Å; I366-F380 HydrophobicContact CD1-CE2 4.17Å; I366-F380 HydrophobicContact CG1-CE2 4.25Å; I366-F380 HydrophobicContact CG1-CZ 4.46Å; I366-F380 WeakPolarHBondContact O-CZ 3.42Å; I366-L411 HydrophobicContact CD1-CD1 3.91Å; I366-L411 HydrophobicContact CD1-CD2 3.85Å; I366-L411 HydrophobicContact CD1-CG 4.44Å; I366-F430 HydrophobicContact CD1-CB 3.95Å; I366-F430 HydrophobicContact CD1-CD2 4.4Å; I366-F430 HydrophobicContact CD1-CG 4.5Å; I366-F430 HydrophobicContact CG1-CB 3.66Å; I366-F430 WeakPolarHBondContact CG1-O 3.22Å; I366-F430 PolarHBondContact N-O 3.5Å; I366-F430 PolarHBondContact O-N 3.06Å; I366-V432 HydrophobicContact CB-CG2 4.38Å; I366-V432 HydrophobicContact CD1-CG2 4.47Å; I366-V432 HydrophobicContact CG1-CG2 4.11Å; I366-V432 HydrophobicContact CG2-CG2 3.56Å
367Y94.1Very high91.7Very high77 Ų7760.5 Ų60.530%0.30233%0.33SS..EExtended strand (participates in β ladder)trans-138.7146.3178.2-161.5-100.7000109.8V269 G270 F365 P428V269-Y367 CarbonylContact C-O 3.49Å; V269-Y367 WeakPolarHBondContact CA-O 3.42Å; G270-Y367 PolarHBondContact N-O 2.91Å; G270-Y367 PolarHBondContact O-N 3.5Å; F365-Y367 HydrophobicContact CE1-CD2 4.09Å; Y367-P428 VanDerWaalsContact CD2-O 3.3Å; Y367-P428 WeakPolarHBondContact CD2-O 3.32Å; Y367-P428 HydrophobicContact CE2-CG 4.48Å; Y367-P428 VanDerWaalsContact CE2-O 3.28Å; Y367-P428 WeakPolarHBondContact CE2-O 3.4Å
368P94Very high91.7Very high15 Ų1558.3 Ų58.310%0.09733%0.33CS..EExtended strand (participates in β ladder)trans-68141.2-176.226.9-35.2000112.4A377 F380P368-A377 HydrophobicContact CB-CB 4.28Å; P368-A377 HydrophobicContact CG-CB 4.15Å; P368-F380 HydrophobicContact CB-CB 3.94Å; P368-F380 HydrophobicContact CB-CD1 4.45Å; P368-F380 HydrophobicContact CB-CD2 4.27Å; P368-F380 HydrophobicContact CB-CG 3.99Å; P368-F380 HydrophobicContact CG-CB 4.16Å; P368-F380 HydrophobicContact CG-CD1 3.92Å; P368-F380 HydrophobicContact CG-CE1 4.4Å; P368-F380 HydrophobicContact CG-CG 3.97Å
369E89.8Confident91.7Very high28 Ų2858.8 Ų58.813%0.13133%0.333CS..  trans-107.683.7176-68-80.715000109.7R256 A268 Y272 G371 E372 V373R256-E369 IonicContact CZ-OE2 2.64Å; R256-E369 IonicContact NE-OE2 3.2Å; R256-E369 PolarHBondContact NE-OE2 3.08Å; R256-E369 IonicContact NH2-OE2 2.9Å; A268-E369 HydrophobicContact CB-CB 4.1Å; A268-E369 PolarHBondContact O-N 2.96Å; Y272-E369 PolarHBondContact OH-OE1 2.83Å; E369-G371 PolarHBondContact O-N 2.87Å; E369-E372 HydrophobicContact CB-CB 4.43Å; E369-E372 HydrophobicContact CB-CG 4.18Å; E369-E372 PolarHBondContact O-N 3.32Å; E369-V373 PolarHBondContact O-N 2.93Å
370E88Confident91.8Very high80 Ų8053.6 Ų53.637%0.37431%0.309SS..THydrogen-bonded Turntrans-62.9-26-178-16764.8-164.300112.9E372 V373 K374 G375 S376 A377E370-E372 VanDerWaalsContact C-N 3.3Å; E370-E372 PolarHBondContact O-N 3.11Å; E370-V373 CarbonylContact O-C 3.51Å; E370-K374 WeakPolarHBondContact OE1-CA 3.35Å; E370-G375 PolarHBondContact OE1-N 2.83Å; E370-G375 PolarHBondContact OE2-N 3.48Å; E370-S376 PolarHBondContact OE2-N 3.19Å; E370-S376 VanDerWaalsContact OE2-N 3.09Å; E370-A377 VanDerWaalsContact OE2-CB 3.31Å; E370-A377 WeakPolarHBondContact OE2-CB 3.22Å; E370-A377 PolarHBondContact OE2-N 3.1Å
371G84.6Confident91.9Very high82 Ų8252.9 Ų52.985%0.84531%0.309SS*.THydrogen-bonded Turntrans-67.5-26.6177.700000114.2E369E369-G371 PolarHBondContact O-N 2.87Å
372E86.5Confident92.1Very high125 Ų12553 Ų5358%0.58432%0.32SS*.THydrogen-bonded Turntrans-88.3-49.1179.5-65-72.917500111A268 E369 E370A268-E372 HydrophobicContact CB-CB 3.71Å; E369-E372 HydrophobicContact CB-CB 4.43Å; E369-E372 HydrophobicContact CB-CG 4.18Å; E369-E372 PolarHBondContact O-N 3.32Å; E370-E372 VanDerWaalsContact C-N 3.3Å; E370-E372 PolarHBondContact O-N 3.11Å
373V89.2Confident92.3Very high65 Ų6551.2 Ų51.239%0.39431%0.308SS..SBendtrans-133.8111.1179.6177.70000109.6A268 E369 E370 S376A268-V373 HydrophobicContact CB-CB 3.84Å; A268-V373 HydrophobicContact CB-CG2 3.85Å; E369-V373 PolarHBondContact O-N 2.93Å; E370-V373 CarbonylContact O-C 3.51Å; V373-S376 WeakPolarHBondContact CB-OG 3.3Å; V373-S376 WeakPolarHBondContact O-CB 3.48Å; V373-S376 PolarHBondContact O-N 3.43Å; V373-S376 PolarHBondContact O-OG 3.34Å
374K91.3Very high92.4Very high191 Ų19150.5 Ų50.583%0.8330%0.301SS*.THydrogen-bonded Turntrans-63.2138176.8-64.4-174.7179.5-176.80111.4E370E370-K374 WeakPolarHBondContact OE1-CA 3.35Å
375G90.2Very high92.5Very high38 Ų3855.8 Ų55.839%0.39232%0.323SS..THydrogen-bonded Turntrans90.3-4.3-174.400000114.1E370 C378 L379E370-G375 PolarHBondContact OE1-N 2.83Å; E370-G375 PolarHBondContact OE2-N 3.48Å; G375-C378 PolarHBondContact O-N 2.96Å; G375-L379 PolarHBondContact O-N 2.98Å
376S92.1Very high92.6Very high2 Ų260.4 Ų60.41%0.01434%0.344CS..Hα-helixtrans-61.3-45.7179.2-69.30000111.7A268 E370 V373 C378 L379 F380A268-S376 PolarHBondContact N-OG 3.02Å; A268-S376 VanDerWaalsContact N-OG 3.09Å; E370-S376 PolarHBondContact OE2-N 3.19Å; E370-S376 VanDerWaalsContact OE2-N 3.09Å; V373-S376 WeakPolarHBondContact CB-OG 3.3Å; V373-S376 WeakPolarHBondContact O-CB 3.48Å; V373-S376 PolarHBondContact O-N 3.43Å; V373-S376 PolarHBondContact O-OG 3.34Å; S376-C378 VanDerWaalsContact C-N 3.31Å; S376-C378 PolarHBondContact O-N 2.68Å; S376-L379 PolarHBondContact O-N 3.11Å; S376-F380 WeakPolarHBondContact O-CB 3.28Å; S376-F380 PolarHBondContact O-N 2.55Å
377A91.9Very high92.6Very high39 Ų3960.5 Ų60.532%0.32234%0.344SS..Hα-helixtrans-62.1-38.8179.700000112.3P368 E370 S381P368-A377 HydrophobicContact CB-CB 4.28Å; P368-A377 HydrophobicContact CG-CB 4.15Å; E370-A377 VanDerWaalsContact OE2-CB 3.31Å; E370-A377 WeakPolarHBondContact OE2-CB 3.22Å; E370-A377 PolarHBondContact OE2-N 3.1Å; A377-S381 VanDerWaalsContact O-CB 3.22Å; A377-S381 WeakPolarHBondContact O-CB 3.43Å; A377-S381 PolarHBondContact O-N 3.29Å
378C93.3Very high92.7Very high98 Ų9860.1 Ų60.166%0.66235%0.346SS*.Hα-helixtrans-64-52.6178.1-177.20000111.5G375 S376 F380 S381 A382G375-C378 PolarHBondContact O-N 2.96Å; S376-C378 VanDerWaalsContact C-N 3.31Å; S376-C378 PolarHBondContact O-N 2.68Å; C378-F380 PolarHBondContact O-N 3.16Å; C378-S381 PolarHBondContact O-N 2.98Å; C378-A382 PolarHBondContact O-N 3.29Å
379L93.7Very high92.9Very high58 Ų5865.4 Ų65.430%0.30437%0.37SS..Hα-helixtrans-65.9-40.2180-178.854.9000111.8L261 L265 V267 G375 S376 A382 L383L261-L379 HydrophobicContact CD1-CD2 4.23Å; L265-L379 HydrophobicContact CD1-CD2 3.75Å; L265-L379 HydrophobicContact CD2-CD2 4.18Å; L265-L379 HydrophobicContact CG-CD2 4.04Å; V267-L379 HydrophobicContact CG2-CB 4.22Å; V267-L379 HydrophobicContact CG2-CD2 3.46Å; V267-L379 VanDerWaalsContact CG2-CD2 3.46Å; V267-L379 HydrophobicContact CG2-CG 3.9Å; G375-L379 PolarHBondContact O-N 2.98Å; S376-L379 PolarHBondContact O-N 3.11Å; L379-A382 PolarHBondContact O-N 3.35Å; L379-L383 WeakPolarHBondContact O-CB 3.44Å; L379-L383 PolarHBondContact O-N 3.44Å
380F95.4Very high93.2Very high6 Ų673.1 Ų73.13%0.02640%0.398CS..Hα-helixtrans-62.1-44.1176-173.5-80.3000111.8V267 V269 I366 P368 S376 C378 L383 L384 F430V267-F380 HydrophobicContact CG1-CB 4.39Å; V269-F380 HydrophobicContact CG1-CD2 4.03Å; V269-F380 HydrophobicContact CG1-CE2 4.08Å; I366-F380 HydrophobicContact CD1-CE2 4.17Å; I366-F380 HydrophobicContact CG1-CE2 4.25Å; I366-F380 HydrophobicContact CG1-CZ 4.46Å; I366-F380 WeakPolarHBondContact O-CZ 3.42Å; P368-F380 HydrophobicContact CB-CB 3.94Å; P368-F380 HydrophobicContact CB-CD1 4.45Å; P368-F380 HydrophobicContact CB-CD2 4.27Å; P368-F380 HydrophobicContact CB-CG 3.99Å; P368-F380 HydrophobicContact CG-CB 4.16Å; P368-F380 HydrophobicContact CG-CD1 3.92Å; P368-F380 HydrophobicContact CG-CE1 4.4Å; P368-F380 HydrophobicContact CG-CG 3.97Å; S376-F380 WeakPolarHBondContact O-CB 3.28Å; S376-F380 PolarHBondContact O-N 2.55Å; C378-F380 PolarHBondContact O-N 3.16Å; F380-L383 PolarHBondContact O-N 2.72Å; F380-L384 WeakPolarHBondContact O-CB 3.19Å; F380-L384 PolarHBondContact O-N 2.76Å; F380-F430 HydrophobicContact CD1-CE2 4.44Å; F380-F430 HydrophobicContact CD2-CD2 4.5Å; F380-F430 HydrophobicContact CD2-CE2 4.43Å; F380-F430 AromaticContact CE1-CD2 3.96Å; F380-F430 HydrophobicContact CE1-CD2 3.96Å; F380-F430 HydrophobicContact CE1-CE2 4.05Å; F380-F430 AromaticContact CE2-CD2 3.7Å; F380-F430 HydrophobicContact CE2-CD2 3.7Å; F380-F430 HydrophobicContact CE2-CE2 4.06Å; F380-F430 AromaticContact CZ-CD2 3.4Å; F380-F430 HydrophobicContact CZ-CD2 3.4Å; F380-F430 AromaticContact CZ-CE2 3.87Å; F380-F430 HydrophobicContact CZ-CE2 3.87Å
381S94.6Very high93.6Very high44 Ų4473.9 Ų73.931%0.30840%0.404SS..Hα-helixtrans-63.1-42176.5-172.30000111.9A377 C378 L384 K385A377-S381 VanDerWaalsContact O-CB 3.22Å; A377-S381 WeakPolarHBondContact O-CB 3.43Å; A377-S381 PolarHBondContact O-N 3.29Å; C378-S381 PolarHBondContact O-N 2.98Å; S381-L384 PolarHBondContact O-N 2.59Å; S381-K385 WeakPolarHBondContact O-CG 3.28Å; S381-K385 PolarHBondContact O-N 3.4Å
382A95.5Very high94.2Very high50 Ų5071.1 Ų71.141%0.41337%0.371SS..Hα-helixtrans-62-43.8175.200000111.8C378 L379 K386C378-A382 PolarHBondContact O-N 3.29Å; L379-A382 PolarHBondContact O-N 3.35Å; A382-K386 WeakPolarHBondContact O-CB 3Å; A382-K386 WeakPolarHBondContact O-CG 3.38Å; A382-K386 PolarHBondContact O-N 3Å
383L95.5Very high94.7Very high24 Ų2465.4 Ų65.413%0.12634%0.344CS..Hα-helixtrans-61.9-45.8176.4-172.467.1000111.4F348 L379 F380 K386 C387 F430F348-L383 HydrophobicContact CE1-CD1 3.73Å; F348-L383 HydrophobicContact CZ-CD1 3.66Å; L379-L383 WeakPolarHBondContact O-CB 3.44Å; L379-L383 PolarHBondContact O-N 3.44Å; F380-L383 PolarHBondContact O-N 2.72Å; L383-K386 PolarHBondContact O-N 2.8Å; L383-C387 WeakPolarHBondContact O-CB 3.49Å; L383-C387 PolarHBondContact O-N 3.12Å; L383-C387 PolarHBondContact O-SG 2.86Å; L383-F430 HydrophobicContact CB-CZ 4.32Å; L383-F430 HydrophobicContact CD2-CE2 4.26Å; L383-F430 HydrophobicContact CD2-CZ 4.04Å; L383-F430 HydrophobicContact CG-CE2 4.43Å; L383-F430 HydrophobicContact CG-CZ 3.87Å
384L96.1Very high95.1Very high17 Ų1762.3 Ų62.39%0.08933%0.326CS..Hα-helixtrans-58.4-54.5178.7178.657000111F380 S381 K386 C387 I388 P413 P428 G429 F430F380-L384 WeakPolarHBondContact O-CB 3.19Å; F380-L384 PolarHBondContact O-N 2.76Å; S381-L384 PolarHBondContact O-N 2.59Å; L384-K386 VanDerWaalsContact C-N 3.34Å; L384-K386 PolarHBondContact O-N 2.55Å; L384-C387 PolarHBondContact O-N 3.42Å; L384-I388 HydrophobicContact CD1-CD1 3.83Å; L384-I388 HydrophobicContact CD1-CG1 4.36Å; L384-I388 HydrophobicContact CG-CD1 3.94Å; L384-I388 WeakPolarHBondContact O-CD1 3.41Å; L384-I388 VanDerWaalsContact O-CG1 3.28Å; L384-I388 WeakPolarHBondContact O-CG1 3.31Å; L384-I388 PolarHBondContact O-N 3.01Å; L384-I388 VanDerWaalsContact O-N 3.07Å; L384-P413 HydrophobicContact CD1-CB 3.55Å; L384-P428 HydrophobicContact CD2-CB 4.42Å; L384-G429 VanDerWaalsContact CD1-O 3.22Å; L384-G429 WeakPolarHBondContact CD1-O 3.34Å; L384-F430 VanDerWaalsContact CA-CZ 3.5Å; L384-F430 HydrophobicContact CB-CE2 3.99Å; L384-F430 HydrophobicContact CB-CZ 4Å; L384-F430 HydrophobicContact CD1-CE1 4.35Å; L384-F430 HydrophobicContact CD1-CE2 4.26Å; L384-F430 HydrophobicContact CD1-CZ 4.12Å
385K96Very high95.4Very high123 Ų12354.1 Ų54.154%0.53529%0.291SS..Hα-helixtrans-56.6-46.3179-70.6174.7-176.4177.70111.7S381 I388 E389S381-K385 WeakPolarHBondContact O-CG 3.28Å; S381-K385 PolarHBondContact O-N 3.4Å; K385-I388 PolarHBondContact O-N 3.14Å; K385-E389 WeakPolarHBondContact O-CG 3.24Å; K385-E389 PolarHBondContact O-N 3.19Å
386K96.8Very high95.8Very high107 Ų10752.3 Ų52.347%0.46527%0.272SS..Hα-helixtrans-71.1-31.1-179.2-67.8-57.2176.9-151.60114.2A382 L383 L384 E389 R390A382-K386 WeakPolarHBondContact O-CB 3Å; A382-K386 WeakPolarHBondContact O-CG 3.38Å; A382-K386 PolarHBondContact O-N 3Å; L383-K386 PolarHBondContact O-N 2.8Å; L384-K386 VanDerWaalsContact C-N 3.34Å; L384-K386 PolarHBondContact O-N 2.55Å; K386-E389 VanDerWaalsContact CD-OE2 3.29Å; K386-E389 WeakPolarHBondContact CD-OE2 3.24Å; K386-E389 IonicContact NZ-OE1 3.13Å; K386-E389 PolarHBondContact NZ-OE1 3.18Å; K386-E389 IonicContact NZ-OE2 2.68Å; K386-E389 PolarHBondContact NZ-OE2 3.1Å; K386-R390 WeakPolarHBondContact O-CB 3.1Å; K386-R390 WeakPolarHBondContact O-CG 3.24Å; K386-R390 PolarHBondContact O-N 3Å
387C96.8Very high95.9Very high2 Ų255.3 Ų55.31%0.01428%0.283CS..Hα-helixtrans-68.4-38.8173.5-68.70000111.6L383 L384 N391 V392 P413 F430L383-C387 WeakPolarHBondContact O-CB 3.49Å; L383-C387 PolarHBondContact O-N 3.12Å; L383-C387 PolarHBondContact O-SG 2.86Å; L384-C387 PolarHBondContact O-N 3.42Å; C387-N391 PolarHBondContact O-N 3.13Å; C387-N391 VanDerWaalsContact O-N 3.07Å; C387-V392 HydrophobicContact CB-CG2 4.28Å; C387-V392 WeakPolarHBondContact CB-O 3.49Å; C387-V392 PolarHBondContact O-N 3.15Å; C387-P413 HydrophobicContact CB-CB 3.96Å; C387-P413 HydrophobicContact CB-CG 3.73Å; C387-F430 HydrophobicContact CB-CE1 4.18Å
388I96.1Very high96Very high68 Ų6853.5 Ų53.535%0.34927%0.268SS..Hα-helixtrans-64.8-53.7175.4-63.4159.9000110.5L384 K385 R390 N391 P413 T415L384-I388 HydrophobicContact CD1-CD1 3.83Å; L384-I388 HydrophobicContact CD1-CG1 4.36Å; L384-I388 HydrophobicContact CG-CD1 3.94Å; L384-I388 WeakPolarHBondContact O-CD1 3.41Å; L384-I388 VanDerWaalsContact O-CG1 3.28Å; L384-I388 WeakPolarHBondContact O-CG1 3.31Å; L384-I388 PolarHBondContact O-N 3.01Å; L384-I388 VanDerWaalsContact O-N 3.07Å; K385-I388 PolarHBondContact O-N 3.14Å; I388-R390 PolarHBondContact O-N 2.76Å; I388-R390 VanDerWaalsContact O-N 3.15Å; I388-N391 PolarHBondContact O-N 3.02Å; I388-P413 HydrophobicContact CD1-CB 4.44Å; I388-P413 HydrophobicContact CG1-CB 3.68Å; I388-P413 HydrophobicContact CG1-CG 4.24Å; I388-T415 HydrophobicContact CD1-CG2 3.48Å; I388-T415 VanDerWaalsContact CD1-CG2 3.48Å; I388-T415 HydrophobicContact CG1-CG2 4.27Å; I388-T415 HydrophobicContact CG2-CG2 4.4Å
389E96.8Very high96Very high126 Ų12649 Ų4959%0.58924%0.237SC*.Hα-helixtrans-54.6-36.8-179.5-76174.6-15300112.6K385 K386K385-E389 WeakPolarHBondContact O-CG 3.24Å; K385-E389 PolarHBondContact O-N 3.19Å; K386-E389 VanDerWaalsContact CD-OE2 3.29Å; K386-E389 WeakPolarHBondContact CD-OE2 3.24Å; K386-E389 IonicContact NZ-OE1 3.13Å; K386-E389 PolarHBondContact NZ-OE1 3.18Å; K386-E389 IonicContact NZ-OE2 2.68Å; K386-E389 PolarHBondContact NZ-OE2 3.1Å
390R96.6Very high95.5Very high191 Ų19148.1 Ų48.172%0.72123%0.232SC*.THydrogen-bonded Turntrans-94.5-1-177-65.1-175.9176.4-163.5-0.8113.9K386 I388 V392K386-R390 WeakPolarHBondContact O-CB 3.1Å; K386-R390 WeakPolarHBondContact O-CG 3.24Å; K386-R390 PolarHBondContact O-N 3Å; I388-R390 PolarHBondContact O-N 2.76Å; I388-R390 VanDerWaalsContact O-N 3.15Å; R390-V392 VanDerWaalsContact C-N 3.31Å; R390-V392 HydrophobicContact CB-CG1 4.29Å; R390-V392 HydrophobicContact CB-CG2 4.01Å; R390-V392 WeakPolarHBondContact O-CG1 3.46Å; R390-V392 PolarHBondContact O-N 2.97Å
391N96.9Very high95Very high95 Ų9552 Ų5251%0.50825%0.246SC..THydrogen-bonded Turntrans50.847.6-175.4-164.928.8000113.3M351 C387 I388M351-N391 WeakPolarHBondContact CG-O 3.47Å; M351-N391 VanDerWaalsContact CG-OD1 3.24Å; M351-N391 WeakPolarHBondContact CG-OD1 3.3Å; M351-N391 PolarHBondContact N-O 3.11Å; M351-N391 VanDerWaalsContact N-O 3.09Å; C387-N391 PolarHBondContact O-N 3.13Å; C387-N391 VanDerWaalsContact O-N 3.07Å; I388-N391 PolarHBondContact O-N 3.02Å
392V97.8Very high94.6Very high25 Ų2559.2 Ų59.215%0.15227%0.266CS..EExtended strand (participates in β ladder)trans-123.4154.5-179.4-640000111.5F348 K349 C387 R390 P413F348-V392 HydrophobicContact CB-CB 4.37Å; F348-V392 HydrophobicContact CB-CG2 4.31Å; F348-V392 HydrophobicContact CD1-CG2 4.21Å; K349-V392 CarbonylContact O-C 3.52Å; K349-V392 VanDerWaalsContact O-CA 3.26Å; K349-V392 WeakPolarHBondContact O-CA 3.39Å; K349-V392 WeakPolarHBondContact O-CB 3.46Å; C387-V392 HydrophobicContact CB-CG2 4.28Å; C387-V392 WeakPolarHBondContact CB-O 3.49Å; C387-V392 PolarHBondContact O-N 3.15Å; R390-V392 VanDerWaalsContact C-N 3.31Å; R390-V392 HydrophobicContact CB-CG1 4.29Å; R390-V392 HydrophobicContact CB-CG2 4.01Å; R390-V392 WeakPolarHBondContact O-CG1 3.46Å; R390-V392 PolarHBondContact O-N 2.97Å; V392-P413 WeakPolarHBondContact O-CD 3.42Å
393F97.3Very high94.2Very high5 Ų559.4 Ų59.42%0.02226%0.261CS..EExtended strand (participates in β ladder)trans-109.9151.8166.768.7-94000110.4F348 K349 P350 M351 L354 L395 A410 L411 V412F348-F393 WeakPolarHBondContact CA-O 3.31Å; K349-F393 HydrophobicContact CB-CD1 4.27Å; K349-F393 HydrophobicContact CB-CE1 3.62Å; K349-F393 HydrophobicContact CB-CE2 3.92Å; K349-F393 HydrophobicContact CB-CZ 3.44Å; K349-F393 VanDerWaalsContact CB-CZ 3.44Å; K349-F393 HydrophobicContact CD-CE2 4.5Å; K349-F393 HydrophobicContact CD-CZ 4.05Å; K349-F393 HydrophobicContact CG-CZ 4.34Å; K349-F393 PolarHBondContact N-O 2.8Å; K349-F393 VanDerWaalsContact O-CD1 3.3Å; K349-F393 WeakPolarHBondContact O-CD1 3.41Å; K349-F393 PolarHBondContact O-N 3.48Å; P350-F393 WeakPolarHBondContact O-CE1 3.45Å; M351-F393 HydrophobicContact CE-CB 4.23Å; M351-F393 HydrophobicContact SD-CB 3.99Å; M351-F393 HydrophobicContact SD-CD1 4.07Å; L354-F393 HydrophobicContact CB-CD1 4.33Å; L354-F393 HydrophobicContact CB-CE1 3.92Å; F393-L395 HydrophobicContact CE2-CB 4.32Å; F393-A410 HydrophobicContact CD2-CB 3.37Å; F393-A410 HydrophobicContact CE2-CB 3.55Å; F393-A410 HydrophobicContact CG-CB 4.08Å; F393-A410 HydrophobicContact CZ-CB 4.39Å; F393-L411 WeakPolarHBondContact CA-O 3.49Å; F393-L411 WeakPolarHBondContact CB-O 3.47Å; F393-V412 HydrophobicContact CB-CG2 4.18Å
394A97.4Very high93.7Very high0 Ų059.3 Ų59.30%026%0.259CS..EExtended strand (participates in β ladder)trans-87121.5175.200000109.7L345 F348 L411L345-A394 HydrophobicContact CD1-CB 3.76Å; F348-A394 HydrophobicContact CD1-CB 3.94Å; F348-A394 HydrophobicContact CE1-CB 3.73Å; A394-L411 HydrophobicContact CB-CB 3.98Å; A394-L411 HydrophobicContact CB-CD1 4.3Å; A394-L411 HydrophobicContact CB-CG 4.42Å; A394-L411 PolarHBondContact N-O 3.25Å; A394-L411 PolarHBondContact O-N 2.62Å
395L97.8Very high93.4Very high19 Ų1961.2 Ų61.210%0.09927%0.272CS..EExtended strand (participates in β ladder)trans-84.9120.8174.8178.466.3000108.8I346 G347 K349 F393 F408 L435I346-L395 HydrophobicContact CB-CD2 4.43Å; I346-L395 HydrophobicContact CB-CG 4.33Å; I346-L395 WeakPolarHBondContact CB-O 3.42Å; I346-L395 HydrophobicContact CD1-CG 4.29Å; I346-L395 HydrophobicContact CG2-CD2 4.34Å; I346-L395 PolarHBondContact N-O 2.71Å; G347-L395 PolarHBondContact N-O 2.8Å; G347-L395 PolarHBondContact O-N 2.69Å; K349-L395 HydrophobicContact CD-CD2 4.33Å; F393-L395 HydrophobicContact CE2-CB 4.32Å; L395-F408 HydrophobicContact CD1-CB 4.45Å; L395-L435 HydrophobicContact CD1-CD1 3.57Å
396C96.8Very high93.3Very high0 Ų056.3 Ų56.30%025%0.253CS..EExtended strand (participates in β ladder)trans-125.6154-179.1-630000111.7F344 F408 V409 L411F344-C396 CarbonylContact O-C 3.33Å; F344-C396 WeakPolarHBondContact O-CA 3.43Å; F344-C396 WeakPolarHBondContact O-CB 3.36Å; C396-F408 WeakPolarHBondContact O-CA 3.34Å; C396-V409 HydrophobicContact CB-CG2 3.82Å; C396-V409 PolarHBondContact N-O 2.64Å; C396-V409 PolarHBondContact O-N 3.35Å; C396-L411 HydrophobicContact CB-CD1 4.49Å; C396-L411 HydrophobicContact CB-CG 4.44Å; C396-L411 WeakPolarHBondContact SG-CD1 3.49Å
397R95.9Very high93.1Very high64 Ų6454 Ų5424%0.24224%0.241CC..EExtended strand (participates in β ladder)trans-93.1121.6161.9-176-177.366.8-154.8-4.8108.2H339 L343 F344 I346 P406 R407H339-R397 PolarHBondContact CD2-NE 3.47Å; H339-R397 PolarHBondContact CD2-NH1 3.26Å; H339-R397 PolarHBondContact CE1-NH1 2.93Å; H339-R397 VanDerWaalsContact CE1-NH1 3.29Å; H339-R397 VanDerWaalsContact NE2-CZ 3.27Å; H339-R397 PolarHBondContact NE2-NH1 2.92Å; L343-R397 WeakPolarHBondContact CA-O 3.28Å; F344-R397 HydrophobicContact CB-CB 4.43Å; F344-R397 PolarHBondContact N-O 3.04Å; F344-R397 PolarHBondContact O-N 3.06Å; I346-R397 HydrophobicContact CD1-CB 4.19Å; R397-P406 HydrophobicContact CG-CB 3.6Å; R397-R407 CarbonylContact C-O 3.5Å
398S93.9Very high93.1Very high2 Ų257.7 Ų57.71%0.01426%0.257CS..EExtended strand (participates in β ladder)trans-105.9134.1178.568.60000112R407 V409S398-R407 PolarHBondContact N-O 2.77Å; S398-R407 PolarHBondContact O-N 3.25Å; S398-R407 PolarHBondContact OG-O 3.02Å; S398-V409 VanDerWaalsContact OG-CG1 3.3Å; S398-V409 WeakPolarHBondContact OG-CG1 3.37Å
399V92.4Very high93.1Very high2 Ų254.5 Ų54.51%0.01224%0.241CC..EExtended strand (participates in β ladder)trans-129.2114.5164.7179.40000107.1H339 P341 G342 R401 P406H339-V399 HydrophobicContact CB-CG2 4.23Å; P341-V399 CarbonylContact C-O 3.55Å; P341-V399 VanDerWaalsContact CA-O 3.24Å; P341-V399 WeakPolarHBondContact CA-O 3.4Å; G342-V399 PolarHBondContact N-O 2.92Å; G342-V399 PolarHBondContact O-N 3.19Å; V399-R401 VanDerWaalsContact CG1-O 3.24Å; V399-R401 WeakPolarHBondContact CG1-O 3.29Å; V399-P406 HydrophobicContact CG2-CB 3.85Å
400F83.4Confident93.2Very high41 Ų4148.5 Ų48.518%0.1821%0.213CC..  trans-86.1-30-174.2-77.2-91.5000113.3L257 V271 V364 Y434L257-F400 HydrophobicContact CD1-CD1 3.83Å; L257-F400 HydrophobicContact CD1-CE1 3.99Å; L257-F400 HydrophobicContact CD1-CG 4.48Å; V271-F400 HydrophobicContact CB-CE1 4.44Å; V271-F400 HydrophobicContact CG1-CE1 3.78Å; V271-F400 HydrophobicContact CG2-CE1 3.99Å; V364-F400 HydrophobicContact CG2-CE1 4.42Å; V364-F400 HydrophobicContact CG2-CZ 4.19Å; F400-Y434 AromaticContact CE2-CE1 3.73Å; F400-Y434 HydrophobicContact CE2-CE1 3.73Å; F400-Y434 HydrophobicContact CZ-CE1 4.16Å; F400-Y434 VanDerWaalsContact CZ-OH 3.3Å; F400-Y434 WeakPolarHBondContact CZ-OH 2.89Å
401R83.9Confident93.2Very high88 Ų8839.4 Ų39.433%0.33218%0.179SC..SBendtrans-142161.9-177.761.5-176.4170.9151.2-4.5111.4E21 V399 Y404E21-R401 IonicContact OE1-CZ 3.85Å; E21-R401 IonicContact OE1-NE 2.79Å; E21-R401 PolarHBondContact OE1-NE 3.29Å; E21-R401 VanDerWaalsContact OE1-NE 3.13Å; E21-R401 IonicContact OE1-NH2 3.91Å; E21-R401 PolarHBondContact OE1-NH2 3.12Å; V399-R401 VanDerWaalsContact CG1-O 3.24Å; V399-R401 WeakPolarHBondContact CG1-O 3.29Å; R401-Y404 HydrophobicContact CG-CD2 4.13Å; R401-Y404 HydrophobicContact CG-CG 4.11Å; R401-Y404 WeakPolarHBondContact O-CB 3.4Å
402R86.3Confident93.3Very high194 Ų19436 Ų3673%0.73216%0.161SC*.THydrogen-bonded Turntrans-63.6151.2176.7-67.9-175.6177.2-178.7-0.4109.7P341 Y404P341-R402 HydrophobicContact CG-CG 3.75Å; R402-Y404 VanDerWaalsContact C-N 3.26Å; R402-Y404 PolarHBondContact O-N 3.3Å
403N86.8Confident93.2Very high55 Ų5535.6 Ų35.629%0.29416%0.159SC..THydrogen-bonded Turntrans5738.4178.6-49.6-17.5000112.8D333 K336D333-N403 HydrophobicContact CB-CB 4.45Å; K336-N403 WeakPolarHBondContact CB-O 3.47Å; K336-N403 CarbonylContact O-C 3.58Å
404Y86.6Confident93.1Very high22 Ų2237.2 Ų37.29%0.08617%0.166CC..  trans-125.5136179.5-164.2-92.4000111.2E21 K336 R401 R402E21-Y404 WeakPolarHBondContact OE1-CE2 3.19Å; E21-Y404 PolarHBondContact OE2-OH 3.29Å; K336-Y404 CarbonylContact O-C 3.47Å; K336-Y404 PolarHBondContact O-N 2.66Å; R401-Y404 HydrophobicContact CG-CD2 4.13Å; R401-Y404 HydrophobicContact CG-CG 4.11Å; R401-Y404 WeakPolarHBondContact O-CB 3.4Å; R402-Y404 VanDerWaalsContact C-N 3.26Å; R402-Y404 PolarHBondContact O-N 3.3Å
405P89.7Confident92.9Very high57 Ų5741.2 Ų41.237%0.3719%0.191SC..  trans-61.8141.3177.9-24.534.8000112.8F338F338-P405 HydrophobicContact CD2-CB 4.46Å; F338-P405 HydrophobicContact CE2-CB 4.33Å
406P93.3Very high92.5Very high20 Ų2044.5 Ų44.513%0.1321%0.206CC..  trans-69.3149.2179.129.2-32.5000110.8F338 R397 V399 Y437F338-P406 HydrophobicContact CB-CG 4.13Å; F338-P406 HydrophobicContact CD1-CG 4.4Å; F338-P406 HydrophobicContact CG-CG 4.18Å; R397-P406 HydrophobicContact CG-CB 3.6Å; V399-P406 HydrophobicContact CG2-CB 3.85Å; P406-Y437 PolarHBondContact O-OH 3.18Å; P406-Y437 VanDerWaalsContact O-OH 3.04Å
407R93.4Very high92.1Very high57 Ų5749.8 Ų49.822%0.21523%0.231CC..EExtended strand (participates in β ladder)trans-125.1148.8169.8-66.1-172.1177.7-96.83.1110.7R397 S398 Y437R397-R407 CarbonylContact C-O 3.5Å; S398-R407 PolarHBondContact N-O 2.77Å; S398-R407 PolarHBondContact O-N 3.25Å; S398-R407 PolarHBondContact OG-O 3.02Å; R407-Y437 HydrophobicContact CG-CE2 4.28Å
408F96.2Very high91.4Very high81 Ų8150.6 Ų50.636%0.35524%0.242SC..EExtended strand (participates in β ladder)trans-81.2135.9169.5-66.2-61.7000110.4I346 L395 C396 L435 Y437I346-F408 HydrophobicContact CD1-CD1 3.57Å; I346-F408 HydrophobicContact CD1-CE1 3.34Å; L395-F408 HydrophobicContact CD1-CB 4.45Å; C396-F408 WeakPolarHBondContact O-CA 3.34Å; F408-L435 HydrophobicContact CB-CB 4.28Å; F408-L435 HydrophobicContact CB-CD1 4.26Å; F408-L435 WeakPolarHBondContact O-CB 3.37Å; F408-L435 PolarHBondContact O-N 3.23Å; F408-Y437 AromaticContact CD2-CE1 3.66Å; F408-Y437 HydrophobicContact CD2-CE1 3.66Å; F408-Y437 AromaticContact CD2-CZ 3.83Å; F408-Y437 AromaticContact CE2-CE1 3.69Å; F408-Y437 HydrophobicContact CE2-CE1 3.69Å
409V96.9Very high90.5Very high0 Ų052.1 Ų52.10%025%0.25CS..EExtended strand (participates in β ladder)trans-132.3145.2178.2-59.90000110.3L343 C396 S398 L411 V432 I433 Y434L343-V409 HydrophobicContact CD2-CG2 4.1Å; C396-V409 HydrophobicContact CB-CG2 3.82Å; C396-V409 PolarHBondContact N-O 2.64Å; C396-V409 PolarHBondContact O-N 3.35Å; S398-V409 VanDerWaalsContact OG-CG1 3.3Å; S398-V409 WeakPolarHBondContact OG-CG1 3.37Å; V409-L411 HydrophobicContact CG2-CD2 4.32Å; V409-V432 HydrophobicContact CB-CG1 3.6Å; V409-V432 HydrophobicContact CG1-CG1 3.76Å; V409-V432 HydrophobicContact CG2-CG1 3.8Å; V409-I433 CarbonylContact C-O 3.46Å; V409-I433 VanDerWaalsContact CA-O 3.28Å; V409-I433 WeakPolarHBondContact CA-O 3.2Å; V409-Y434 HydrophobicContact CG1-CD1 3.51Å; V409-Y434 HydrophobicContact CG1-CE1 3.81Å; V409-Y434 HydrophobicContact CG1-CG 4.38Å
410A97.7Very high89.5Confident0 Ų061.5 Ų61.50%029%0.294CS..EExtended strand (participates in β ladder)trans-98.5118.5169.200000108.8L354 F393 V412 I433 L435L354-A410 HydrophobicContact CD1-CB 4.12Å; L354-A410 HydrophobicContact CD2-CB 4.47Å; F393-A410 HydrophobicContact CD2-CB 3.37Å; F393-A410 HydrophobicContact CE2-CB 3.55Å; F393-A410 HydrophobicContact CG-CB 4.08Å; F393-A410 HydrophobicContact CZ-CB 4.39Å; A410-V412 HydrophobicContact CB-CG2 4.35Å; A410-V412 PolarHBondContact O-N 2.9Å; A410-I433 HydrophobicContact CB-CB 4.39Å; A410-I433 PolarHBondContact N-O 2.89Å; A410-I433 PolarHBondContact O-N 3.34Å; A410-L435 HydrophobicContact CB-CD1 4.43Å; A410-L435 HydrophobicContact CB-CD2 4.17Å; A410-L435 HydrophobicContact CB-CG 4.45Å
411L97.7Very high88.5Confident1 Ų161.1 Ų61.11%0.00530%0.301CS..EExtended strand (participates in β ladder)trans-83.695.9168.4-53.7-173.7000108.1L259 I366 F393 A394 C396 V409 P413 F430 N431 V432L259-L411 HydrophobicContact CD1-CD1 4.16Å; I366-L411 HydrophobicContact CD1-CD1 3.91Å; I366-L411 HydrophobicContact CD1-CD2 3.85Å; I366-L411 HydrophobicContact CD1-CG 4.44Å; F393-L411 WeakPolarHBondContact CA-O 3.49Å; F393-L411 WeakPolarHBondContact CB-O 3.47Å; A394-L411 HydrophobicContact CB-CB 3.98Å; A394-L411 HydrophobicContact CB-CD1 4.3Å; A394-L411 HydrophobicContact CB-CG 4.42Å; A394-L411 PolarHBondContact N-O 3.25Å; A394-L411 PolarHBondContact O-N 2.62Å; C396-L411 HydrophobicContact CB-CD1 4.49Å; C396-L411 HydrophobicContact CB-CG 4.44Å; C396-L411 WeakPolarHBondContact SG-CD1 3.49Å; V409-L411 HydrophobicContact CG2-CD2 4.32Å; L411-P413 WeakPolarHBondContact O-CD 3.24Å; L411-F430 HydrophobicContact CB-CB 4.09Å; L411-F430 HydrophobicContact CB-CD1 3.87Å; L411-F430 HydrophobicContact CB-CG 4.17Å; L411-N431 CarbonylContact C-O 3.57Å; L411-N431 WeakPolarHBondContact CA-O 3.29Å; L411-V432 HydrophobicContact CD2-CB 4.24Å; L411-V432 HydrophobicContact CD2-CG1 4.15Å; L411-V432 HydrophobicContact CD2-CG2 3.7Å
412V97.3Very high87.8Confident22 Ų2260.8 Ų60.813%0.13330%0.302CS..EExtended strand (participates in β ladder)trans-85.9114.4179.81710000108.4M351 L354 F393 A410 F430 N431 I433M351-V412 HydrophobicContact CE-CB 4.35Å; M351-V412 HydrophobicContact CE-CG1 3.72Å; M351-V412 HydrophobicContact SD-CG1 4.39Å; M351-V412 HydrophobicContact SD-CG2 4.48Å; L354-V412 HydrophobicContact CD2-CG2 3.51Å; F393-V412 HydrophobicContact CB-CG2 4.18Å; A410-V412 HydrophobicContact CB-CG2 4.35Å; A410-V412 PolarHBondContact O-N 2.9Å; V412-F430 CarbonylContact O-C 3.55Å; V412-F430 VanDerWaalsContact O-CA 3.29Å; V412-F430 WeakPolarHBondContact O-CA 3.09Å; V412-N431 HydrophobicContact CB-CB 4.31Å; V412-N431 PolarHBondContact N-O 3.09Å; V412-N431 PolarHBondContact O-N 2.95Å; V412-I433 HydrophobicContact CB-CD1 4.32Å; V412-I433 HydrophobicContact CG2-CD1 3.7Å; V412-I433 HydrophobicContact CG2-CG1 4.15Å
413P97Very high87Confident17 Ų1752.3 Ų52.311%0.1127%0.272CS..EExtended strand (participates in β ladder)trans-58.7138.7175.525.1-39.5000112.1M351 L384 C387 I388 V392 L411 F430M351-P413 VanDerWaalsContact CE-CD 3.46Å; M351-P413 HydrophobicContact CE-CG 3.62Å; L384-P413 HydrophobicContact CD1-CB 3.55Å; C387-P413 HydrophobicContact CB-CB 3.96Å; C387-P413 HydrophobicContact CB-CG 3.73Å; I388-P413 HydrophobicContact CD1-CB 4.44Å; I388-P413 HydrophobicContact CG1-CB 3.68Å; I388-P413 HydrophobicContact CG1-CG 4.24Å; V392-P413 WeakPolarHBondContact O-CD 3.42Å; L411-P413 WeakPolarHBondContact O-CD 3.24Å; P413-F430 HydrophobicContact CB-CD1 4.1Å; P413-F430 HydrophobicContact CB-CE1 3.85Å
414Q94.9Very high86.7Confident39 Ų3952.5 Ų52.518%0.18227%0.271CS..EExtended strand (participates in β ladder)trans-128.5125.4178.2-177.1171.2-84.400109.7T426 P427 G429 N431Q414-T426 HydrophobicContact CG-CG2 3.38Å; Q414-P427 PolarHBondContact NE2-O 3.04Å; Q414-G429 PolarHBondContact N-O 3.46Å; Q414-G429 PolarHBondContact O-N 2.8Å; Q414-N431 PolarHBondContact OE1-ND2 2.83Å
415T93Very high86.4Confident84 Ų8456.2 Ų56.252%0.51529%0.291SS..  trans-80.9152.6172.647.20000110.8I388I388-T415 HydrophobicContact CD1-CG2 3.48Å; I388-T415 VanDerWaalsContact CD1-CG2 3.48Å; I388-T415 HydrophobicContact CG1-CG2 4.27Å; I388-T415 HydrophobicContact CG2-CG2 4.4Å
416E90.1Very high86.3Confident89 Ų8954.9 Ų54.942%0.41628%0.283SS..  trans-67.2136.8170.4-175.4166.6-143.300111.1V418 Q424 T426 P428E416-V418 HydrophobicContact CG-CG1 4.3Å; E416-Q424 PolarHBondContact OE1-NE2 2.85Å; E416-T426 VanDerWaalsContact CA-O 3.31Å; E416-T426 WeakPolarHBondContact CA-O 3.35Å; E416-P428 HydrophobicContact CB-CB 4Å; E416-P428 HydrophobicContact CB-CG 4.07Å
417E87.6Confident86.1Confident111 Ų11155.6 Ų55.652%0.51929%0.287SS..EExtended strand (participates in β ladder)trans-131129.6171.4-169-179.4-179.100108.7I425 T426E417-I425 HydrophobicContact CG-CD1 4.41Å; E417-I425 PolarHBondContact O-N 3.46Å; E417-T426 PolarHBondContact N-O 2.91Å; E417-T426 PolarHBondContact O-N 2.72Å; E417-T426 VanDerWaalsContact O-N 3.09Å; E417-T426 PolarHBondContact OE2-OG1 2.75Å
418V81.6Confident86.1Confident80 Ų8054.2 Ų54.249%0.48529%0.285SS..EExtended strand (participates in β ladder)trans-117.9144.9178.7-65.20000109.5E416 V423E416-V418 HydrophobicContact CG-CG1 4.3Å; V418-V423 CarbonylContact C-O 3.59Å; V418-V423 WeakPolarHBondContact CA-O 3.39Å
419D74.6Confident86Confident34 Ų3450.3 Ų50.318%0.18227%0.268CS..  trans-78.6178.1174.678.5-0.5000112.4K242 G421 K422 V423 I425K242-D419 IonicContact NZ-OD2 3.02Å; D419-G421 PolarHBondContact O-N 3.34Å; D419-G421 VanDerWaalsContact OD1-C 3.22Å; D419-G421 VanDerWaalsContact OD1-CA 3.26Å; D419-G421 WeakPolarHBondContact OD1-CA 3.31Å; D419-G421 PolarHBondContact OD1-N 3.13Å; D419-K422 PolarHBondContact O-N 2.59Å; D419-K422 PolarHBondContact OD1-N 3.37Å; D419-K422 VanDerWaalsContact OD1-N 3.11Å; D419-V423 PolarHBondContact N-O 2.7Å; D419-V423 WeakPolarHBondContact OD1-CA 3.39Å; D419-V423 WeakPolarHBondContact OD1-CB 3.41Å; D419-V423 PolarHBondContact OD1-N 3.49Å; D419-I425 HydrophobicContact CB-CD1 3.64Å; D419-I425 HydrophobicContact CB-CG1 3.85Å
420E71.9Confident86Confident200 Ų20050.3 Ų50.394%0.93527%0.268SS*.THydrogen-bonded Turntrans-58.4-30.4177-66.8175.6-175.900112.4K422E420-K422 PolarHBondContact O-N 3.41Å
421G63Low86Confident32 Ų3251.9 Ų51.933%0.3328%0.277SS..THydrogen-bonded Turntrans-84.211.9175.300000114.1D419 V423D419-G421 PolarHBondContact O-N 3.34Å; D419-G421 VanDerWaalsContact OD1-C 3.22Å; D419-G421 VanDerWaalsContact OD1-CA 3.26Å; D419-G421 WeakPolarHBondContact OD1-CA 3.31Å; D419-G421 PolarHBondContact OD1-N 3.13Å; G421-V423 PolarHBondContact O-N 3.23Å; G421-V423 VanDerWaalsContact O-N 3.16Å
422K68.3Low85.9Confident81 Ų8151.9 Ų51.935%0.35228%0.277SS..SBendtrans5821.2-175.3-58.5173.7-177.2151.60113.5G228 L229 E232 D419 E420G228-K422 WeakPolarHBondContact O-CB 3.49Å; L229-K422 WeakPolarHBondContact CD2-O 3.43Å; E232-K422 IonicContact OE1-NZ 3.84Å; E232-K422 PolarHBondContact OE1-NZ 3.3Å; D419-K422 PolarHBondContact O-N 2.59Å; D419-K422 PolarHBondContact OD1-N 3.37Å; D419-K422 VanDerWaalsContact OD1-N 3.11Å; E420-K422 PolarHBondContact O-N 3.41Å
423V70.2Confident85.9Confident17 Ų1752.7 Ų52.710%0.10328%0.28CS..  trans-81.1127.7172-175.30000108.4L229 V418 D419 G421 I425L229-V423 HydrophobicContact CD2-CB 4.34Å; L229-V423 HydrophobicContact CD2-CG1 4.49Å; L229-V423 HydrophobicContact CD2-CG2 4.12Å; V418-V423 CarbonylContact C-O 3.59Å; V418-V423 WeakPolarHBondContact CA-O 3.39Å; D419-V423 PolarHBondContact N-O 2.7Å; D419-V423 WeakPolarHBondContact OD1-CA 3.39Å; D419-V423 WeakPolarHBondContact OD1-CB 3.41Å; D419-V423 PolarHBondContact OD1-N 3.49Å; G421-V423 PolarHBondContact O-N 3.23Å; G421-V423 VanDerWaalsContact O-N 3.16Å; V423-I425 PolarHBondContact O-N 3.31Å; V423-I425 VanDerWaalsContact O-N 3.15Å
424Q79.4Confident85.8Confident59 Ų5952.6 Ų52.628%0.27628%0.277SS..EExtended strand (participates in β ladder)trans-63.8115.1176.7-172.5-179.379.900110.1E416E416-Q424 PolarHBondContact OE1-NE2 2.85Å
425I81.3Confident85.8Confident99 Ų9952.1 Ų52.151%0.50828%0.276SS..EExtended strand (participates in β ladder)trans-83.2-48.5172.6-59.9166.1000108.9E417 D419 V423E417-I425 HydrophobicContact CG-CD1 4.41Å; E417-I425 PolarHBondContact O-N 3.46Å; D419-I425 HydrophobicContact CB-CD1 3.64Å; D419-I425 HydrophobicContact CB-CG1 3.85Å; V423-I425 PolarHBondContact O-N 3.31Å; V423-I425 VanDerWaalsContact O-N 3.15Å
426T87.4Confident86Confident30 Ų3049.4 Ų49.418%0.18426%0.26CS..EExtended strand (participates in β ladder)trans-126.4118.7-172.4-56.10000108.8Q414 E416 E417Q414-T426 HydrophobicContact CG-CG2 3.38Å; E416-T426 VanDerWaalsContact CA-O 3.31Å; E416-T426 WeakPolarHBondContact CA-O 3.35Å; E417-T426 PolarHBondContact N-O 2.91Å; E417-T426 PolarHBondContact O-N 2.72Å; E417-T426 VanDerWaalsContact O-N 3.09Å; E417-T426 PolarHBondContact OE2-OG1 2.75Å
427P89.4Confident86.3Confident35 Ų3548.6 Ų48.623%0.22725%0.254CS..  trans-76.8148.6-178.828.8-34.5000112.6F365 Q414F365-P427 HydrophobicContact CE1-CB 4.15Å; F365-P427 HydrophobicContact CE1-CG 4.09Å; F365-P427 HydrophobicContact CE2-CG 4.07Å; F365-P427 HydrophobicContact CZ-CB 3.85Å; F365-P427 HydrophobicContact CZ-CG 3.76Å; Q414-P427 PolarHBondContact NE2-O 3.04Å
428P92.4Very high86.6Confident27 Ų2747.2 Ų47.218%0.17526%0.261CS..SBendtrans-74.6128.4175.127.5-30.3000111.7F365 Y367 L384 E416F365-P428 WeakPolarHBondContact CZ-O 3.47Å; Y367-P428 VanDerWaalsContact CD2-O 3.3Å; Y367-P428 WeakPolarHBondContact CD2-O 3.32Å; Y367-P428 HydrophobicContact CE2-CG 4.48Å; Y367-P428 VanDerWaalsContact CE2-O 3.28Å; Y367-P428 WeakPolarHBondContact CE2-O 3.4Å; L384-P428 HydrophobicContact CD2-CB 4.42Å; E416-P428 HydrophobicContact CB-CB 4Å; E416-P428 HydrophobicContact CB-CG 4.07Å
429G95.1Very high87.2Confident0 Ų050 Ų500%027%0.273CS..EExtended strand (participates in β ladder)trans164.8-150.117900000113.8L384 Q414L384-G429 VanDerWaalsContact CD1-O 3.22Å; L384-G429 WeakPolarHBondContact CD1-O 3.34Å; Q414-G429 PolarHBondContact N-O 3.46Å; Q414-G429 PolarHBondContact O-N 2.8Å
430F97.1Very high88.1Confident0 Ų051.7 Ų51.70%028%0.282CS..EExtended strand (participates in β ladder)trans-122.8133.1172.9-64.1-95.1000111.5F365 I366 F380 L383 L384 C387 L411 V412 P413F365-F430 WeakPolarHBondContact CD2-O 3.19Å; I366-F430 HydrophobicContact CD1-CB 3.95Å; I366-F430 HydrophobicContact CD1-CD2 4.4Å; I366-F430 HydrophobicContact CD1-CG 4.5Å; I366-F430 HydrophobicContact CG1-CB 3.66Å; I366-F430 WeakPolarHBondContact CG1-O 3.22Å; I366-F430 PolarHBondContact N-O 3.5Å; I366-F430 PolarHBondContact O-N 3.06Å; F380-F430 HydrophobicContact CD1-CE2 4.44Å; F380-F430 HydrophobicContact CD2-CD2 4.5Å; F380-F430 HydrophobicContact CD2-CE2 4.43Å; F380-F430 AromaticContact CE1-CD2 3.96Å; F380-F430 HydrophobicContact CE1-CD2 3.96Å; F380-F430 HydrophobicContact CE1-CE2 4.05Å; F380-F430 AromaticContact CE2-CD2 3.7Å; F380-F430 HydrophobicContact CE2-CD2 3.7Å; F380-F430 HydrophobicContact CE2-CE2 4.06Å; F380-F430 AromaticContact CZ-CD2 3.4Å; F380-F430 HydrophobicContact CZ-CD2 3.4Å; F380-F430 AromaticContact CZ-CE2 3.87Å; F380-F430 HydrophobicContact CZ-CE2 3.87Å; L383-F430 HydrophobicContact CB-CZ 4.32Å; L383-F430 HydrophobicContact CD2-CE2 4.26Å; L383-F430 HydrophobicContact CD2-CZ 4.04Å; L383-F430 HydrophobicContact CG-CE2 4.43Å; L383-F430 HydrophobicContact CG-CZ 3.87Å; L384-F430 VanDerWaalsContact CA-CZ 3.5Å; L384-F430 HydrophobicContact CB-CE2 3.99Å; L384-F430 HydrophobicContact CB-CZ 4Å; L384-F430 HydrophobicContact CD1-CE1 4.35Å; L384-F430 HydrophobicContact CD1-CE2 4.26Å; L384-F430 HydrophobicContact CD1-CZ 4.12Å; C387-F430 HydrophobicContact CB-CE1 4.18Å; L411-F430 HydrophobicContact CB-CB 4.09Å; L411-F430 HydrophobicContact CB-CD1 3.87Å; L411-F430 HydrophobicContact CB-CG 4.17Å; V412-F430 CarbonylContact O-C 3.55Å; V412-F430 VanDerWaalsContact O-CA 3.29Å; V412-F430 WeakPolarHBondContact O-CA 3.09Å; P413-F430 HydrophobicContact CB-CD1 4.1Å; P413-F430 HydrophobicContact CB-CE1 3.85Å
431N96.4Very high89.2Confident32 Ų3246.8 Ų46.817%0.17126%0.262CS..EExtended strand (participates in β ladder)trans-79.3127.3163.3-69.8-57.1000109.4L411 V412 Q414 I433L411-N431 CarbonylContact C-O 3.57Å; L411-N431 WeakPolarHBondContact CA-O 3.29Å; V412-N431 HydrophobicContact CB-CB 4.31Å; V412-N431 PolarHBondContact N-O 3.09Å; V412-N431 PolarHBondContact O-N 2.95Å; Q414-N431 PolarHBondContact OE1-ND2 2.83Å; N431-I433 HydrophobicContact CB-CG1 4.36Å; N431-I433 PolarHBondContact O-N 3.39Å
432V96.3Very high90.6Very high1 Ų155.3 Ų55.31%0.00628%0.284CS..EExtended strand (participates in β ladder)trans-89.999.9172.7-171.50000108S363 V364 I366 V409 L411S363-V432 WeakPolarHBondContact CA-O 3.31Å; S363-V432 WeakPolarHBondContact CB-O 3.44Å; V364-V432 HydrophobicContact CG2-CB 3.54Å; V364-V432 HydrophobicContact CG2-CG1 4.05Å; V364-V432 HydrophobicContact CG2-CG2 3.81Å; V364-V432 PolarHBondContact N-O 2.92Å; V364-V432 WeakPolarHBondContact O-CB 3.17Å; V364-V432 PolarHBondContact O-N 2.88Å; I366-V432 HydrophobicContact CB-CG2 4.38Å; I366-V432 HydrophobicContact CD1-CG2 4.47Å; I366-V432 HydrophobicContact CG1-CG2 4.11Å; I366-V432 HydrophobicContact CG2-CG2 3.56Å; V409-V432 HydrophobicContact CB-CG1 3.6Å; V409-V432 HydrophobicContact CG1-CG1 3.76Å; V409-V432 HydrophobicContact CG2-CG1 3.8Å; L411-V432 HydrophobicContact CD2-CB 4.24Å; L411-V432 HydrophobicContact CD2-CG1 4.15Å; L411-V432 HydrophobicContact CD2-CG2 3.7Å
433I96.4Very high91.7Very high39 Ų3958.5 Ų58.520%0.231%0.31CS..EExtended strand (participates in β ladder)trans-95.7119.3177.9-57.6-171.8000108.9L354 V409 A410 V412 N431L354-I433 HydrophobicContact CD2-CD1 4.1Å; V409-I433 CarbonylContact C-O 3.46Å; V409-I433 VanDerWaalsContact CA-O 3.28Å; V409-I433 WeakPolarHBondContact CA-O 3.2Å; A410-I433 HydrophobicContact CB-CB 4.39Å; A410-I433 PolarHBondContact N-O 2.89Å; A410-I433 PolarHBondContact O-N 3.34Å; V412-I433 HydrophobicContact CB-CD1 4.32Å; V412-I433 HydrophobicContact CG2-CD1 3.7Å; V412-I433 HydrophobicContact CG2-CG1 4.15Å; N431-I433 HydrophobicContact CB-CG1 4.36Å; N431-I433 PolarHBondContact O-N 3.39Å
434Y95.3Very high92.6Very high15 Ų1564.5 Ų64.56%0.05934%0.341CS..EExtended strand (participates in β ladder)trans-72.2130.8178.3-59.7-79000111.2R361 P362 V364 F400 V409R361-Y434 HydrophobicContact CG-CD2 3.34Å; R361-Y434 HydrophobicContact CG-CE2 3.94Å; R361-Y434 HydrophobicContact CG-CG 3.81Å; R361-Y434 VanDerWaalsContact NE-CD1 3.34Å; R361-Y434 VanDerWaalsContact NE-CD2 3.29Å; P362-Y434 WeakPolarHBondContact O-CD2 2.91Å; P362-Y434 VanDerWaalsContact O-CE2 3.24Å; P362-Y434 WeakPolarHBondContact O-CE2 3.3Å; V364-Y434 WeakPolarHBondContact CG2-OH 3.34Å; F400-Y434 AromaticContact CE2-CE1 3.73Å; F400-Y434 HydrophobicContact CE2-CE1 3.73Å; F400-Y434 HydrophobicContact CZ-CE1 4.16Å; F400-Y434 VanDerWaalsContact CZ-OH 3.3Å; F400-Y434 WeakPolarHBondContact CZ-OH 2.89Å; V409-Y434 HydrophobicContact CG1-CD1 3.51Å; V409-Y434 HydrophobicContact CG1-CE1 3.81Å; V409-Y434 HydrophobicContact CG1-CG 4.38Å
435L96.1Very high93.1Very high30 Ų3069.5 Ų69.516%0.15737%0.37CS..PPolyproline II helixtrans-97.6137.1-179.9-58.1179.1000110.3L354 L395 F408 A410L354-L435 HydrophobicContact CD1-CD2 3.64Å; L395-L435 HydrophobicContact CD1-CD1 3.57Å; F408-L435 HydrophobicContact CB-CB 4.28Å; F408-L435 HydrophobicContact CB-CD1 4.26Å; F408-L435 WeakPolarHBondContact O-CB 3.37Å; F408-L435 PolarHBondContact O-N 3.23Å; A410-L435 HydrophobicContact CB-CD1 4.43Å; A410-L435 HydrophobicContact CB-CD2 4.17Å; A410-L435 HydrophobicContact CB-CG 4.45Å
436P96.1Very high93.2Very high27 Ų2769.1 Ų69.118%0.17537%0.374CS..PPolyproline II helixtrans-66.7142.7176.724.7-30.9000111.1H358 I360 D440 L441H358-P436 HydrophobicContact CB-CG 3.92Å; H358-P436 WeakPolarHBondContact O-CD 3.4Å; I360-P436 HydrophobicContact CG2-CB 3.7Å; I360-P436 HydrophobicContact CG2-CG 4.3Å; P436-D440 WeakPolarHBondContact CA-OD2 3.28Å; P436-D440 HydrophobicContact CB-CB 3.69Å; P436-L441 HydrophobicContact CB-CD2 4.25Å; P436-L441 HydrophobicContact CG-CD2 4.11Å
437Y95.6Very high93.2Very high72 Ų7272.9 Ų72.928%0.28240%0.399SS..PPolyproline II helixtrans-77.4172.6159.8-79.2-73.5000110.6P406 R407 F408 D439 D440P406-Y437 PolarHBondContact O-OH 3.18Å; P406-Y437 VanDerWaalsContact O-OH 3.04Å; R407-Y437 HydrophobicContact CG-CE2 4.28Å; F408-Y437 AromaticContact CD2-CE1 3.66Å; F408-Y437 HydrophobicContact CD2-CE1 3.66Å; F408-Y437 AromaticContact CD2-CZ 3.83Å; F408-Y437 AromaticContact CE2-CE1 3.69Å; F408-Y437 HydrophobicContact CE2-CE1 3.69Å; Y437-D439 PolarHBondContact O-N 3.38Å; Y437-D440 PolarHBondContact N-OD2 3.06Å; Y437-D440 PolarHBondContact O-N 3.04Å; Y437-D440 VanDerWaalsContact O-N 3.15Å
438A95.4Very high92.9Very high81 Ų8183.4 Ų83.467%0.66943%0.434SS*.G310 helixtrans-58.1-36.2177.100000112D440 L441A438-D440 PolarHBondContact O-N 3.09Å; A438-L441 PolarHBondContact O-N 3.07Å
439D94.1Very high92.4Very high139 Ų13986.8 Ų86.874%0.74346%0.457SS*.G310 helixtrans-66.5-24179.8-51.8-81.5000113.6Y437Y437-D439 PolarHBondContact O-N 3.38Å
440D94.1Very high91.9Very high70 Ų7092.4 Ų92.437%0.37449%0.494SS..G310 helixtrans-79.9-20.9178.9-59.7-46.2000111.9P436 Y437 A438P436-D440 WeakPolarHBondContact CA-OD2 3.28Å; P436-D440 HydrophobicContact CB-CB 3.69Å; Y437-D440 PolarHBondContact N-OD2 3.06Å; Y437-D440 PolarHBondContact O-N 3.04Å; Y437-D440 VanDerWaalsContact O-N 3.15Å; A438-D440 PolarHBondContact O-N 3.09Å
441L93.1Very high91.5Very high96 Ų9698.4 Ų98.450%0.50353%0.533SS..PPolyproline II helixtrans-83.2126.5-177.2-63.7175.8000111.2P436 A438P436-L441 HydrophobicContact CB-CD2 4.25Å; P436-L441 HydrophobicContact CG-CD2 4.11Å; A438-L441 PolarHBondContact O-N 3.07Å
442R92.6Very high91.3Very high212 Ų212100 Ų10080%0.855%0.55SS**PPolyproline II helixtrans-103.1125.2178.9-58-60.2-177.6149-1.6110.9
443T91.2Very high91.2Very high147 Ų147102.6 Ų102.690%0.90257%0.568SS**PPolyproline II helixtrans-74.5126.7172.4-50.40000109.8
444L89.9Confident91.1Very high144 Ų144106.4 Ų106.475%0.75459%0.585SS**  trans-108.3141.8176.4-56.5176.9000109.4P446L444-P446 VanDerWaalsContact O-CD 3.24Å; L444-P446 WeakPolarHBondContact O-CD 3.4Å
445D89.4Confident91Very high163 Ų163109.7 Ų109.787%0.87261%0.607SS**  trans-108.982.5169.3-172.219.9000108.8
446P84.6Confident90.9Very high92 Ų92110.4 Ų110.460%0.59761%0.609SS**  trans-70.4141.5-174.328.5-34.2000111L444 R448L444-P446 VanDerWaalsContact O-CD 3.24Å; L444-P446 WeakPolarHBondContact O-CD 3.4Å; P446-R448 PolarHBondContact O-N 3.15Å
447P86.6Confident90.9Very high109 Ų109111.6 Ų111.671%0.70862%0.616SS**  trans-61139.617427-33.7000110.2C449P447-C449 PolarHBondContact O-N 2.97Å
448R83.6Confident90.8Very high256 Ų256111.5 Ų111.597%0.96662%0.621SS**  trans-73.895.5174.5-65.6-175.7-177.1-174.71.1109.3P446P446-R448 PolarHBondContact O-N 3.15Å
449C81.1Confident90.7Very high97 Ų97109.9 Ų109.966%0.65560%0.598SS**PPolyproline II helixtrans-96.9141.4173.7-62.90000110.4P447P447-C449 PolarHBondContact O-N 2.97Å
450P85.8Confident90.8Very high119 Ų119106.4 Ų106.477%0.77358%0.579SS**PPolyproline II helixtrans-63.4143.5171.727.8-33.2000109.9
451P88.3Confident90.9Very high126 Ų126108.3 Ų108.382%0.81858%0.584SS**PPolyproline II helixtrans-64.5147.7174.228.5-34000110.4
452A91.9Very high91Very high65 Ų65107.4 Ų107.454%0.53758%0.577SS.*PPolyproline II helixtrans-65.1145.6175.300000111.2Q456 V457A452-Q456 HydrophobicContact CB-CB 4.4Å; A452-V457 HydrophobicContact CB-CG2 4.08Å
453S93.8Very high91.1Very high55 Ų5598.2 Ų98.239%0.38554%0.543SS..PPolyproline II helixtrans-68.5155.9173.366.70000111.5T455 Q456 V457S453-T455 PolarHBondContact O-N 3.25Å; S453-Q456 PolarHBondContact O-N 3.41Å; S453-Q456 VanDerWaalsContact O-N 3.13Å; S453-Q456 VanDerWaalsContact OG-CG 3.29Å; S453-Q456 WeakPolarHBondContact OG-CG 3.28Å; S453-Q456 PolarHBondContact OG-N 3.04Å; S453-Q456 PolarHBondContact OG-OE1 2.99Å; S453-V457 WeakPolarHBondContact O-CG2 3.3Å; S453-V457 PolarHBondContact O-N 3.37Å
454Q94.6Very high91.3Very high119 Ų11996.2 Ų96.256%0.55653%0.526SS*.Hα-helixtrans-59.3-32.9178.8-168.458.650.600112.5V457 N458Q454-V457 PolarHBondContact O-N 2.88Å; Q454-N458 PolarHBondContact NE2-OD1 3.35Å; Q454-N458 WeakPolarHBondContact O-CB 3.5Å; Q454-N458 PolarHBondContact O-N 3.36Å; Q454-N458 PolarHBondContact O-ND2 3.35Å; Q454-N458 PolarHBondContact O-OD1 3.07Å
455T93.6Very high91.6Very high84 Ų8496.2 Ų96.252%0.51552%0.522SS..Hα-helixtrans-63.4-46.7176-50.20000111.6S453 V457 N458 K459 L526S453-T455 PolarHBondContact O-N 3.25Å; T455-V457 PolarHBondContact O-N 2.91Å; T455-N458 PolarHBondContact O-N 3.19Å; T455-K459 PolarHBondContact O-N 3.36Å; T455-L526 HydrophobicContact CG2-CD1 4.28Å; T455-L526 HydrophobicContact CG2-CD2 4.36Å
456Q93.2Very high91.8Very high45 Ų4592.2 Ų92.221%0.2150%0.497CS..Hα-helixtrans-63.1-42.4176.1-70.1161-26.300111.2A452 S453 N458 K459 M460 L526 V527A452-Q456 HydrophobicContact CB-CB 4.4Å; S453-Q456 PolarHBondContact O-N 3.41Å; S453-Q456 VanDerWaalsContact O-N 3.13Å; S453-Q456 VanDerWaalsContact OG-CG 3.29Å; S453-Q456 WeakPolarHBondContact OG-CG 3.28Å; S453-Q456 PolarHBondContact OG-N 3.04Å; S453-Q456 PolarHBondContact OG-OE1 2.99Å; Q456-N458 PolarHBondContact O-N 3.03Å; Q456-K459 PolarHBondContact O-N 3.35Å; Q456-M460 PolarHBondContact O-N 2.9Å; Q456-L526 HydrophobicContact CG-CB 4.18Å; Q456-L526 PolarHBondContact NE2-O 3.34Å; Q456-V527 HydrophobicContact CB-CG2 4.46Å; Q456-V527 HydrophobicContact CG-CG2 3.92Å
457V95.6Very high92.3Very high52 Ų5290.8 Ų90.832%0.31548%0.484SS..Hα-helixtrans-61.6-43.6176.7172.90000111.3A452 S453 Q454 T455 M460 K461A452-V457 HydrophobicContact CB-CG2 4.08Å; S453-V457 WeakPolarHBondContact O-CG2 3.3Å; S453-V457 PolarHBondContact O-N 3.37Å; Q454-V457 PolarHBondContact O-N 2.88Å; T455-V457 PolarHBondContact O-N 2.91Å; V457-M460 PolarHBondContact O-N 3.33Å; V457-K461 HydrophobicContact CG1-CD 4.49Å; V457-K461 WeakPolarHBondContact O-CG 3.43Å; V457-K461 PolarHBondContact O-N 3.29Å
458N95Very high92.7Very high71 Ų7195.4 Ų95.438%0.3849%0.487SS..Hα-helixtrans-65.4-41.5179.6-70.7-12.6000111.8Q454 T455 Q456 K461 E462Q454-N458 PolarHBondContact NE2-OD1 3.35Å; Q454-N458 WeakPolarHBondContact O-CB 3.5Å; Q454-N458 PolarHBondContact O-N 3.36Å; Q454-N458 PolarHBondContact O-ND2 3.35Å; Q454-N458 PolarHBondContact O-OD1 3.07Å; T455-N458 PolarHBondContact O-N 3.19Å; Q456-N458 PolarHBondContact O-N 3.03Å; N458-K461 WeakPolarHBondContact O-CB 3.34Å; N458-K461 PolarHBondContact O-N 2.9Å; N458-K461 VanDerWaalsContact O-N 3.16Å; N458-E462 PolarHBondContact O-N 3.24Å; N458-E462 VanDerWaalsContact O-N 3.13Å
459K93.2Very high93.1Very high46 Ų4689.9 Ų89.920%0.247%0.471CS..Hα-helixtrans-63.8-40.5174.3-76.6-54.3-164.9173.90113.1T455 Q456 K461 E462 I463 E522 F523 L526T455-K459 PolarHBondContact O-N 3.36Å; Q456-K459 PolarHBondContact O-N 3.35Å; K459-K461 VanDerWaalsContact C-N 3.29Å; K459-K461 PolarHBondContact O-N 2.64Å; K459-E462 WeakPolarHBondContact CD-OE2 3.43Å; K459-E462 IonicContact NZ-OE2 2.68Å; K459-E462 PolarHBondContact NZ-OE2 2.69Å; K459-E462 WeakPolarHBondContact O-CB 3.41Å; K459-E462 PolarHBondContact O-N 3.43Å; K459-I463 PolarHBondContact O-N 3.41Å; K459-E522 VanDerWaalsContact CE-OE2 3.23Å; K459-E522 WeakPolarHBondContact CE-OE2 3.48Å; K459-E522 IonicContact NZ-OE2 3.64Å; K459-E522 PolarHBondContact NZ-OE2 3.25Å; K459-F523 HydrophobicContact CB-CD2 4.03Å; K459-L526 HydrophobicContact CB-CD1 4.26Å; K459-L526 HydrophobicContact CG-CD1 3.61Å
460M95.5Very high93.6Very high67 Ų6794.3 Ų94.333%0.3348%0.479SS..Hα-helixtrans-63.9-34.1173.1-177.354.564.700112.3Q456 V457 I463 I464 F523Q456-M460 PolarHBondContact O-N 2.9Å; V457-M460 PolarHBondContact O-N 3.33Å; M460-I463 HydrophobicContact CE-CD1 4.49Å; M460-I463 WeakPolarHBondContact O-CB 3.37Å; M460-I463 PolarHBondContact O-N 2.68Å; M460-I463 HydrophobicContact SD-CB 4.33Å; M460-I463 HydrophobicContact SD-CG2 4.27Å; M460-I464 HydrophobicContact CG-CD1 3.95Å; M460-I464 HydrophobicContact CG-CG1 4.43Å; M460-I464 VanDerWaalsContact O-CG1 3.28Å; M460-I464 WeakPolarHBondContact O-CG1 3.3Å; M460-I464 PolarHBondContact O-N 3.13Å; M460-I464 HydrophobicContact SD-CD1 4.36Å; M460-I464 HydrophobicContact SD-CG1 4.27Å; M460-F523 HydrophobicContact CB-CE2 3.97Å; M460-F523 HydrophobicContact CB-CZ 4.5Å; M460-F523 HydrophobicContact CE-CD1 4.08Å; M460-F523 HydrophobicContact CE-CD2 4.33Å; M460-F523 HydrophobicContact CE-CE1 3.46Å; M460-F523 VanDerWaalsContact CE-CE1 3.46Å; M460-F523 HydrophobicContact CE-CE2 3.76Å; M460-F523 HydrophobicContact CE-CG 4.48Å; M460-F523 HydrophobicContact CE-CZ 3.27Å
461K95.8Very high93.9Very high110 Ų11096.2 Ų96.248%0.47847%0.471SS..Hα-helixtrans-63.3-40.4173.7-73.7174.2179.2177.50112.4V457 N458 K459 I463 I464 Q465V457-K461 HydrophobicContact CG1-CD 4.49Å; V457-K461 WeakPolarHBondContact O-CG 3.43Å; V457-K461 PolarHBondContact O-N 3.29Å; N458-K461 WeakPolarHBondContact O-CB 3.34Å; N458-K461 PolarHBondContact O-N 2.9Å; N458-K461 VanDerWaalsContact O-N 3.16Å; K459-K461 VanDerWaalsContact C-N 3.29Å; K459-K461 PolarHBondContact O-N 2.64Å; K461-I463 VanDerWaalsContact C-N 3.33Å; K461-I464 PolarHBondContact O-N 3.42Å; K461-Q465 WeakPolarHBondContact O-CB 3.44Å; K461-Q465 WeakPolarHBondContact O-CG 3.37Å; K461-Q465 PolarHBondContact O-N 3.21Å
462E95Very high93.7Very high76 Ų7695.9 Ų95.936%0.35545%0.454SS..Hα-helixtrans-60.3-44.2174.9-69.9172.7-166.400111N458 K459 Q465 K466 L519N458-E462 PolarHBondContact O-N 3.24Å; N458-E462 VanDerWaalsContact O-N 3.13Å; K459-E462 WeakPolarHBondContact CD-OE2 3.43Å; K459-E462 IonicContact NZ-OE2 2.68Å; K459-E462 PolarHBondContact NZ-OE2 2.69Å; K459-E462 WeakPolarHBondContact O-CB 3.41Å; K459-E462 PolarHBondContact O-N 3.43Å; E462-Q465 PolarHBondContact O-N 3.38Å; E462-K466 PolarHBondContact O-N 3.36Å; E462-K466 VanDerWaalsContact O-N 3.08Å; E462-L519 HydrophobicContact CB-CD1 4.41Å; E462-L519 WeakPolarHBondContact OE2-CD2 3.32Å
463I95.4Very high93.5Very high19 Ų1997.9 Ų97.910%0.09746%0.464CS..Hα-helixtrans-59.5-50.7175.2-68.5171.9000110.8K459 M460 K461 Q465 K466 L467 L516 L519 F523K459-I463 PolarHBondContact O-N 3.41Å; M460-I463 HydrophobicContact CE-CD1 4.49Å; M460-I463 WeakPolarHBondContact O-CB 3.37Å; M460-I463 PolarHBondContact O-N 2.68Å; M460-I463 HydrophobicContact SD-CB 4.33Å; M460-I463 HydrophobicContact SD-CG2 4.27Å; K461-I463 VanDerWaalsContact C-N 3.33Å; I463-Q465 VanDerWaalsContact C-N 3.31Å; I463-Q465 PolarHBondContact O-N 3.33Å; I463-K466 PolarHBondContact O-N 2.79Å; I463-L467 HydrophobicContact CG2-CD1 4.1Å; I463-L467 WeakPolarHBondContact O-CG 3.36Å; I463-L467 PolarHBondContact O-N 3.02Å; I463-L516 HydrophobicContact CB-CD2 4.34Å; I463-L516 HydrophobicContact CG1-CD2 4.38Å; I463-L516 HydrophobicContact CG2-CD2 3.89Å; I463-L519 HydrophobicContact CG1-CB 4.19Å; I463-F523 HydrophobicContact CD1-CB 3.84Å; I463-F523 HydrophobicContact CD1-CD2 4.44Å; I463-F523 HydrophobicContact CD1-CG 4.01Å
464I95.9Very high93Very high105 Ų10599.4 Ų99.454%0.53847%0.468SS..Hα-helixtrans-60.3-40.8179.7-68.7166000111.4M460 K461 K466 L467 R468M460-I464 HydrophobicContact CG-CD1 3.95Å; M460-I464 HydrophobicContact CG-CG1 4.43Å; M460-I464 VanDerWaalsContact O-CG1 3.28Å; M460-I464 WeakPolarHBondContact O-CG1 3.3Å; M460-I464 PolarHBondContact O-N 3.13Å; M460-I464 HydrophobicContact SD-CD1 4.36Å; M460-I464 HydrophobicContact SD-CG1 4.27Å; K461-I464 PolarHBondContact O-N 3.42Å; I464-K466 PolarHBondContact O-N 2.81Å; I464-L467 PolarHBondContact O-N 2.77Å; I464-R468 PolarHBondContact O-N 3.23Å; I464-R468 VanDerWaalsContact O-N 3.11Å
465Q94.8Very high92.6Very high145 Ų14595.6 Ų95.668%0.67846%0.456SS*.Hα-helixtrans-63.1-41.7177.7-76.8179.31.100111.9K461 E462 I463 L467 R468K461-Q465 WeakPolarHBondContact O-CB 3.44Å; K461-Q465 WeakPolarHBondContact O-CG 3.37Å; K461-Q465 PolarHBondContact O-N 3.21Å; E462-Q465 PolarHBondContact O-N 3.38Å; I463-Q465 VanDerWaalsContact C-N 3.31Å; I463-Q465 PolarHBondContact O-N 3.33Å; Q465-L467 VanDerWaalsContact C-N 3.33Å; Q465-L467 PolarHBondContact O-N 3.09Å; Q465-R468 WeakPolarHBondContact O-CB 3.26Å; Q465-R468 PolarHBondContact O-N 2.95Å
466K94.3Very high92.5Very high78 Ų7896 Ų9634%0.33945%0.451SS..Hα-helixtrans-66.3-33.5175.7-75.6-156.1-1801790112.9E462 I463 I464 R468 R515 L516 L519E462-K466 PolarHBondContact O-N 3.36Å; E462-K466 VanDerWaalsContact O-N 3.08Å; I463-K466 PolarHBondContact O-N 2.79Å; I464-K466 PolarHBondContact O-N 2.81Å; K466-R468 VanDerWaalsContact C-N 3.34Å; K466-R515 WeakPolarHBondContact CD-O 3.49Å; K466-R515 PolarHBondContact NZ-O 2.84Å; K466-R515 VanDerWaalsContact O-CD 3.22Å; K466-R515 WeakPolarHBondContact O-CD 3.47Å; K466-R515 PolarHBondContact O-NE 2.87Å; K466-R515 PolarHBondContact O-NH1 2.87Å; K466-R515 VanDerWaalsContact O-NH1 3.17Å; K466-R515 PolarHBondContact O-NH2 2.91Å; K466-L516 HydrophobicContact CB-CD2 4.18Å; K466-L516 PolarHBondContact NZ-O 2.87Å; K466-L519 HydrophobicContact CD-CD1 3.71Å; K466-L519 VanDerWaalsContact CE-CD1 3.45Å; K466-L519 HydrophobicContact CG-CD1 4.38Å
467L95Very high92.3Very high63 Ų6398.8 Ų98.833%0.3346%0.464SS..THydrogen-bonded Turntrans-91.57.9-179.6-59.6179.5000114.1I463 I464 Q465 F469 I512 L516I463-L467 HydrophobicContact CG2-CD1 4.1Å; I463-L467 WeakPolarHBondContact O-CG 3.36Å; I463-L467 PolarHBondContact O-N 3.02Å; I464-L467 PolarHBondContact O-N 2.77Å; Q465-L467 VanDerWaalsContact C-N 3.33Å; Q465-L467 PolarHBondContact O-N 3.09Å; L467-F469 PolarHBondContact O-N 3.44Å; L467-I512 HydrophobicContact CD2-CB 4.48Å; L467-I512 HydrophobicContact CD2-CG1 4.34Å; L467-I512 HydrophobicContact CD2-CG2 3.95Å; L467-L516 HydrophobicContact CD1-CD1 4.16Å; L467-L516 HydrophobicContact CD1-CD2 4.15Å; L467-L516 HydrophobicContact CD2-CD1 4.23Å; L467-L516 HydrophobicContact CD2-CD2 3.93Å; L467-L516 HydrophobicContact CD2-CG 3.97Å; L467-L516 HydrophobicContact CG-CD2 3.85Å; L467-L516 HydrophobicContact CG-CG 4.37Å
468R94.6Very high92.1Very high206 Ų20699.8 Ų99.878%0.77747%0.468SS*.  trans-65.3130.8-179.7-170.3177.8-179.3-174.7-0.7110.9I464 Q465 K466I464-R468 PolarHBondContact O-N 3.23Å; I464-R468 VanDerWaalsContact O-N 3.11Å; Q465-R468 WeakPolarHBondContact O-CB 3.26Å; Q465-R468 PolarHBondContact O-N 2.95Å; K466-R468 VanDerWaalsContact C-N 3.34Å
469F92.9Very high92Very high140 Ų14097.8 Ų97.861%0.61446%0.459SS*.  trans-139.2162.6170.874.9-80.1000110.5L467 F476L467-F469 PolarHBondContact O-N 3.44Å; F469-F476 HydrophobicContact CE2-CZ 4.4Å
470K91.8Very high91.9Very high190 Ų190100.2 Ų100.283%0.82648%0.477SS*.  trans-87.3107.5177.2-173.6177.6-179.5-178.90108.9
471Y91.6Very high91.7Very high158 Ų15897.8 Ų97.862%0.6247%0.465SS*.  trans-70.2138.9174.3174.8-100.7000110.9F476Y471-F476 HydrophobicContact CD2-CE2 4.06Å; Y471-F476 HydrophobicContact CE2-CD2 4.3Å; Y471-F476 AromaticContact CE2-CE2 3.97Å; Y471-F476 HydrophobicContact CE2-CE2 3.97Å
472R85.4Confident91.4Very high120 Ų12094.5 Ų94.545%0.45345%0.452SS..  trans-132.5146.1166.5-55.2-173.1-67.4170.6-3.5108.8D474 A475R472-D474 WeakPolarHBondContact CB-OD1 3.46Å; R472-D474 IonicContact CZ-OD1 3.86Å; R472-D474 IonicContact NE-OD1 3.11Å; R472-D474 PolarHBondContact O-N 3.2Å; R472-A475 HydrophobicContact CB-CB 4.22Å; R472-A475 WeakPolarHBondContact O-CB 3.21Å; R472-A475 PolarHBondContact O-N 3.44Å
473S86.3Confident91.2Very high107 Ų10794.1 Ų94.175%0.74845%0.45SS*.THydrogen-bonded Turntrans-67.7-20.6-179.151.10000113.9
474D83.1Confident91.1Very high87 Ų8794.9 Ų94.947%0.46545%0.453SS..THydrogen-bonded Turntrans-99.94.7-179.965.6-18.5000113.4R472 F476R472-D474 WeakPolarHBondContact CB-OD1 3.46Å; R472-D474 IonicContact CZ-OD1 3.86Å; R472-D474 IonicContact NE-OD1 3.11Å; R472-D474 PolarHBondContact O-N 3.2Å; D474-F476 VanDerWaalsContact C-N 3.31Å; D474-F476 PolarHBondContact O-N 3.1Å
475A87Confident90.7Very high38 Ų3891.1 Ų91.131%0.31443%0.433SS..SBendtrans-75.9-16.6-174.700000114.3R472R472-A475 HydrophobicContact CB-CB 4.22Å; R472-A475 WeakPolarHBondContact O-CB 3.21Å; R472-A475 PolarHBondContact O-N 3.44Å
476F90.4Very high90.4Very high92 Ų9286.6 Ų86.640%0.40441%0.41SS..  trans-125.8130.1-173.5-57-82.3000110.5F469 Y471 D474 L504 I505F469-F476 HydrophobicContact CE2-CZ 4.4Å; Y471-F476 HydrophobicContact CD2-CE2 4.06Å; Y471-F476 HydrophobicContact CE2-CD2 4.3Å; Y471-F476 AromaticContact CE2-CE2 3.97Å; Y471-F476 HydrophobicContact CE2-CE2 3.97Å; D474-F476 VanDerWaalsContact C-N 3.31Å; D474-F476 PolarHBondContact O-N 3.1Å; F476-L504 HydrophobicContact CD1-CB 4.49Å; F476-L504 WeakPolarHBondContact CD1-O 3.22Å; F476-I505 HydrophobicContact CB-CG2 4.41Å; F476-I505 HydrophobicContact CD1-CG2 4.41Å
477E89.4Confident90.2Very high105 Ų10585.9 Ų85.949%0.49141%0.409SS..  trans-96.7156172.8-60.4-172.8173.200110.6P479 Q482 L504E477-P479 VanDerWaalsContact O-CD 3.23Å; E477-P479 WeakPolarHBondContact O-CD 3.43Å; E477-Q482 HydrophobicContact CB-CG 4.06Å; E477-Q482 WeakPolarHBondContact OE2-CG 3.41Å; E477-Q482 PolarHBondContact OE2-NE2 2.96Å; E477-L504 HydrophobicContact CG-CD1 4.42Å
478N91.5Very high89.9Confident73 Ų7386.7 Ų86.739%0.3941%0.414SS..  trans-80.6109.9177-178-28.4000109.8V480 L481 Q482N478-V480 PolarHBondContact O-N 2.79Å; N478-V480 WeakPolarHBondContact OD1-CB 3.38Å; N478-V480 PolarHBondContact OD1-N 2.68Å; N478-L481 HydrophobicContact CB-CB 4.15Å; N478-L481 HydrophobicContact CB-CD1 4.03Å; N478-L481 HydrophobicContact CB-CG 4.11Å; N478-L481 PolarHBondContact O-N 3.39Å; N478-L481 VanDerWaalsContact O-N 3.11Å; N478-L481 PolarHBondContact OD1-N 2.88Å; N478-Q482 WeakPolarHBondContact O-CG 3.45Å; N478-Q482 PolarHBondContact O-N 3.43Å
479P92.3Very high89.5Confident28 Ų2878.7 Ų78.718%0.18239%0.385CS..Hα-helixtrans-62.4-31.7-174.725.7-35.7000112.6E477 Q482 Q483 I501 I505E477-P479 VanDerWaalsContact O-CD 3.23Å; E477-P479 WeakPolarHBondContact O-CD 3.43Å; P479-Q482 PolarHBondContact O-N 2.87Å; P479-Q483 WeakPolarHBondContact O-CB 3.44Å; P479-Q483 PolarHBondContact O-N 3.09Å; P479-I501 WeakPolarHBondContact O-CD1 3.48Å; P479-I505 HydrophobicContact CG-CD1 4.01Å; P479-I505 HydrophobicContact CG-CG1 4.07Å
480V92.3Very high89.2Confident98 Ų9872.3 Ų72.359%0.59436%0.358SS*.Hα-helixtrans-66.9-41.3178.1179.50000111.1N478 H484N478-V480 PolarHBondContact O-N 2.79Å; N478-V480 WeakPolarHBondContact OD1-CB 3.38Å; N478-V480 PolarHBondContact OD1-N 2.68Å; V480-H484 VanDerWaalsContact O-CB 3.32Å; V480-H484 WeakPolarHBondContact O-CB 3.48Å; V480-H484 PolarHBondContact O-N 2.73Å; V480-H484 VanDerWaalsContact O-N 3.11Å
481L91.1Very high89Confident15 Ų1569.3 Ų69.38%0.07935%0.351CS..Hα-helixtrans-70.5-44.8176.4-66.9-180000110.7A278 K280 N478 Q483 H484 F485A278-L481 HydrophobicContact CB-CD1 3.55Å; K280-L481 HydrophobicContact CB-CD2 4.24Å; N478-L481 HydrophobicContact CB-CB 4.15Å; N478-L481 HydrophobicContact CB-CD1 4.03Å; N478-L481 HydrophobicContact CB-CG 4.11Å; N478-L481 PolarHBondContact O-N 3.39Å; N478-L481 VanDerWaalsContact O-N 3.11Å; N478-L481 PolarHBondContact OD1-N 2.88Å; L481-Q483 PolarHBondContact O-N 3.27Å; L481-H484 WeakPolarHBondContact O-CB 3.25Å; L481-H484 PolarHBondContact O-N 3.13Å; L481-H484 VanDerWaalsContact O-N 3.14Å; L481-F485 HydrophobicContact CD2-CE2 4.49Å; L481-F485 WeakPolarHBondContact O-CD2 3.3Å; L481-F485 PolarHBondContact O-N 3.18Å
482Q89.9Confident88.7Confident41 Ų4164.4 Ų64.419%0.19234%0.343CS..Hα-helixtrans-57.4-49178.3-69.3-56.7-16.700111.5E477 N478 P479 H484 F485 R486 I501E477-Q482 HydrophobicContact CB-CG 4.06Å; E477-Q482 WeakPolarHBondContact OE2-CG 3.41Å; E477-Q482 PolarHBondContact OE2-NE2 2.96Å; N478-Q482 WeakPolarHBondContact O-CG 3.45Å; N478-Q482 PolarHBondContact O-N 3.43Å; P479-Q482 PolarHBondContact O-N 2.87Å; Q482-H484 VanDerWaalsContact C-N 3.29Å; Q482-H484 PolarHBondContact O-N 2.94Å; Q482-F485 PolarHBondContact O-N 3.46Å; Q482-R486 WeakPolarHBondContact O-CB 3.24Å; Q482-R486 VanDerWaalsContact O-CG 3.25Å; Q482-R486 WeakPolarHBondContact O-CG 3.45Å; Q482-R486 PolarHBondContact O-N 3.44Å; Q482-I501 HydrophobicContact CB-CD1 3.91Å; Q482-I501 HydrophobicContact CB-CG2 4.48Å
483Q91.3Very high88.5Confident68 Ų6860.1 Ų60.132%0.31833%0.329SS..Hα-helixtrans-61.2-40.9177.5-170.564.851.700111.7P479 L481 N487 I501P479-Q483 WeakPolarHBondContact O-CB 3.44Å; P479-Q483 PolarHBondContact O-N 3.09Å; L481-Q483 PolarHBondContact O-N 3.27Å; Q483-N487 PolarHBondContact NE2-OD1 3.49Å; Q483-N487 WeakPolarHBondContact O-CB 3.5Å; Q483-N487 PolarHBondContact O-N 3.42Å; Q483-N487 PolarHBondContact O-ND2 2.91Å; Q483-N487 PolarHBondContact O-OD1 3.33Å; Q483-I501 HydrophobicContact CB-CD1 3.76Å
484H91.8Very high88.4Confident35 Ų3562.4 Ų62.416%0.16233%0.333CS..Hα-helixtrans-61.3-48.6179.8178.249.6000112.2K280 V480 L481 Q482 N487 L488K280-H484 VanDerWaalsContact CE-CE1 3.44Å; K280-H484 WeakPolarHBondContact CE-CE1 3.24Å; K280-H484 WeakPolarHBondContact CE-ND1 3.41Å; V480-H484 VanDerWaalsContact O-CB 3.32Å; V480-H484 WeakPolarHBondContact O-CB 3.48Å; V480-H484 PolarHBondContact O-N 2.73Å; V480-H484 VanDerWaalsContact O-N 3.11Å; L481-H484 WeakPolarHBondContact O-CB 3.25Å; L481-H484 PolarHBondContact O-N 3.13Å; L481-H484 VanDerWaalsContact O-N 3.14Å; Q482-H484 VanDerWaalsContact C-N 3.29Å; Q482-H484 PolarHBondContact O-N 2.94Å; H484-N487 PolarHBondContact O-N 2.89Å; H484-L488 WeakPolarHBondContact O-CG 3.42Å; H484-L488 PolarHBondContact O-N 3.49Å; H484-L488 VanDerWaalsContact O-N 3.11Å
485F88.6Confident88.4Confident26 Ų2662.2 Ų62.211%0.11433%0.33CS..Hα-helixtrans-72.8-32.8-179-74.4-75000112.7I72 I73 P281 L481 Q482 N487 L488 E489I72-F485 HydrophobicContact CG2-CD1 4.11Å; I72-F485 HydrophobicContact CG2-CE1 4.16Å; I73-F485 HydrophobicContact CB-CD2 4.43Å; I73-F485 HydrophobicContact CB-CE2 4.05Å; I73-F485 HydrophobicContact CB-CZ 4.13Å; I73-F485 HydrophobicContact CD1-CD2 4.27Å; I73-F485 HydrophobicContact CG1-CD1 4.13Å; I73-F485 HydrophobicContact CG1-CD2 3.66Å; I73-F485 HydrophobicContact CG1-CE1 4.21Å; I73-F485 HydrophobicContact CG1-CE2 3.78Å; I73-F485 HydrophobicContact CG1-CG 3.87Å; I73-F485 HydrophobicContact CG1-CZ 4.05Å; I73-F485 HydrophobicContact CG2-CD2 4.32Å; I73-F485 HydrophobicContact CG2-CE2 3.73Å; I73-F485 HydrophobicContact CG2-CZ 4.14Å; P281-F485 HydrophobicContact CG-CE1 4.39Å; P281-F485 HydrophobicContact CG-CZ 3.77Å; L481-F485 HydrophobicContact CD2-CE2 4.49Å; L481-F485 WeakPolarHBondContact O-CD2 3.3Å; L481-F485 PolarHBondContact O-N 3.18Å; Q482-F485 PolarHBondContact O-N 3.46Å; F485-N487 VanDerWaalsContact C-N 3.35Å; F485-L488 HydrophobicContact CD1-CD1 4.25Å; F485-L488 PolarHBondContact O-N 3.44Å; F485-E489 WeakPolarHBondContact O-CB 3.48Å; F485-E489 PolarHBondContact O-N 2.8Å
486R88.2Confident88.2Confident51 Ų5169.3 Ų69.319%0.19236%0.362CS..Hα-helixtrans-62.9-40.6171.6-71.2-69.6168.3-168.6-0.6112.6Q482 L488 E489 A490 E499 I501Q482-R486 WeakPolarHBondContact O-CB 3.24Å; Q482-R486 VanDerWaalsContact O-CG 3.25Å; Q482-R486 WeakPolarHBondContact O-CG 3.45Å; Q482-R486 PolarHBondContact O-N 3.44Å; R486-L488 VanDerWaalsContact C-N 3.35Å; R486-E489 IonicContact CZ-OE2 3.65Å; R486-E489 IonicContact NE-OE2 3.86Å; R486-E489 IonicContact NH1-OE1 2.76Å; R486-E489 IonicContact NH1-OE2 3.32Å; R486-E489 PolarHBondContact NH1-OE2 3.21Å; R486-E489 PolarHBondContact O-N 3.15Å; R486-A490 WeakPolarHBondContact O-CB 3.19Å; R486-A490 PolarHBondContact O-N 3.29Å; R486-E499 IonicContact CZ-OE2 3.12Å; R486-E499 IonicContact NH1-OE2 2.85Å; R486-E499 PolarHBondContact NH1-OE2 2.82Å; R486-E499 VanDerWaalsContact NH1-OE2 3.08Å; R486-I501 HydrophobicContact CG-CG2 3.8Å
487N90.5Very high88Confident62 Ų6268.1 Ų68.133%0.33237%0.369SS..Hα-helixtrans-63.9-40.9173.8-67.7-10.2000111.7Q483 H484 F485 L491 P498Q483-N487 PolarHBondContact NE2-OD1 3.49Å; Q483-N487 WeakPolarHBondContact O-CB 3.5Å; Q483-N487 PolarHBondContact O-N 3.42Å; Q483-N487 PolarHBondContact O-ND2 2.91Å; Q483-N487 PolarHBondContact O-OD1 3.33Å; H484-N487 PolarHBondContact O-N 2.89Å; F485-N487 VanDerWaalsContact C-N 3.35Å; N487-L491 VanDerWaalsContact O-CG 3.28Å; N487-L491 WeakPolarHBondContact O-CG 3.36Å; N487-L491 PolarHBondContact O-N 3.41Å; N487-L491 VanDerWaalsContact O-N 3.09Å; N487-P498 WeakPolarHBondContact OD1-CB 3.46Å; N487-P498 WeakPolarHBondContact OD1-CG 3.35Å
488L88.6Confident87.8Confident80 Ų8065.5 Ų65.542%0.41936%0.361SS..Hα-helixtrans-67.4-39.1176.8-71.8178.3000112.5H484 F485 R486 L491 A492H484-L488 WeakPolarHBondContact O-CG 3.42Å; H484-L488 PolarHBondContact O-N 3.49Å; H484-L488 VanDerWaalsContact O-N 3.11Å; F485-L488 HydrophobicContact CD1-CD1 4.25Å; F485-L488 PolarHBondContact O-N 3.44Å; R486-L488 VanDerWaalsContact C-N 3.35Å; L488-L491 PolarHBondContact O-N 3.11Å; L488-A492 VanDerWaalsContact O-CB 3.25Å; L488-A492 WeakPolarHBondContact O-CB 3.43Å; L488-A492 PolarHBondContact O-N 3.14Å
489E85.1Confident87.4Confident38 Ų3867.2 Ų67.218%0.17837%0.366CS..Hα-helixtrans-60.5-48.9175.2-179.9173.7-144.300110.7F485 R486 L491 A492 L493F485-E489 WeakPolarHBondContact O-CB 3.48Å; F485-E489 PolarHBondContact O-N 2.8Å; R486-E489 IonicContact CZ-OE2 3.65Å; R486-E489 IonicContact NE-OE2 3.86Å; R486-E489 IonicContact NH1-OE1 2.76Å; R486-E489 IonicContact NH1-OE2 3.32Å; R486-E489 PolarHBondContact NH1-OE2 3.21Å; R486-E489 PolarHBondContact O-N 3.15Å; E489-L491 VanDerWaalsContact C-N 3.33Å; E489-L491 PolarHBondContact O-N 3.09Å; E489-A492 PolarHBondContact O-N 3.13Å; E489-L493 HydrophobicContact CG-CD1 3.95Å; E489-L493 WeakPolarHBondContact O-CB 3.34Å; E489-L493 WeakPolarHBondContact O-CG 3.48Å; E489-L493 PolarHBondContact O-N 3.08Å
490A87.2Confident87Confident6 Ų673.6 Ų73.65%0.0540%0.399CS..Hα-helixtrans-59.1-43.2177.200000112.4R486 L493 D494 M495 P498R486-A490 WeakPolarHBondContact O-CB 3.19Å; R486-A490 PolarHBondContact O-N 3.29Å; A490-L493 PolarHBondContact O-N 3.21Å; A490-D494 PolarHBondContact O-N 3.39Å; A490-D494 VanDerWaalsContact O-N 3.13Å; A490-M495 HydrophobicContact CB-CB 4.07Å; A490-M495 HydrophobicContact CB-SD 4.4Å; A490-M495 PolarHBondContact O-N 3.22Å; A490-P498 HydrophobicContact CB-CB 3.93Å
491L87.9Confident86.8Confident128 Ų12871.4 Ų71.467%0.6738%0.383SS*.Hα-helixtrans-67.8-39.2176.7-71.1171.3000112.7N487 L488 E489 L493 D494N487-L491 VanDerWaalsContact O-CG 3.28Å; N487-L491 WeakPolarHBondContact O-CG 3.36Å; N487-L491 PolarHBondContact O-N 3.41Å; N487-L491 VanDerWaalsContact O-N 3.09Å; L488-L491 PolarHBondContact O-N 3.11Å; E489-L491 VanDerWaalsContact C-N 3.33Å; E489-L491 PolarHBondContact O-N 3.09Å; L491-L493 VanDerWaalsContact C-N 3.25Å; L491-L493 PolarHBondContact O-N 2.97Å; L491-D494 PolarHBondContact O-N 3.39Å
492A84.9Confident86.6Confident55 Ų5577.3 Ų77.346%0.45541%0.41SS..Hα-helixtrans-72.4-20.7-179.400000113.2A111 L488 E489A111-A492 HydrophobicContact CB-CB 3.62Å; L488-A492 VanDerWaalsContact O-CB 3.25Å; L488-A492 WeakPolarHBondContact O-CB 3.43Å; L488-A492 PolarHBondContact O-N 3.14Å; E489-A492 PolarHBondContact O-N 3.13Å
493L81.7Confident86.7Confident30 Ų3078.2 Ų78.216%0.15742%0.417CS..THydrogen-bonded Turntrans-107.17.9179.2-63.4177.8000113.1A111 K112 Q115 E489 A490 L491 M495A111-L493 HydrophobicContact CB-CD1 4.18Å; A111-L493 HydrophobicContact CB-CD2 3.75Å; A111-L493 HydrophobicContact CB-CG 3.73Å; K112-L493 HydrophobicContact CG-CD2 4.06Å; Q115-L493 HydrophobicContact CB-CD1 4.48Å; E489-L493 HydrophobicContact CG-CD1 3.95Å; E489-L493 WeakPolarHBondContact O-CB 3.34Å; E489-L493 WeakPolarHBondContact O-CG 3.48Å; E489-L493 PolarHBondContact O-N 3.08Å; A490-L493 PolarHBondContact O-N 3.21Å; L491-L493 VanDerWaalsContact C-N 3.25Å; L491-L493 PolarHBondContact O-N 2.97Å; L493-M495 HydrophobicContact CB-CE 3.99Å; L493-M495 HydrophobicContact CB-CG 4.01Å; L493-M495 HydrophobicContact CB-SD 4.42Å; L493-M495 HydrophobicContact CD1-CE 3.5Å; L493-M495 HydrophobicContact CG-CE 4.39Å; L493-M495 PolarHBondContact O-N 2.79Å
494D84.1Confident86.6Confident155 Ų15578.2 Ų78.283%0.82942%0.419SS*.THydrogen-bonded Turntrans51.538.1-177.7-62.4-54.3000113.3A490 L491A490-D494 PolarHBondContact O-N 3.39Å; A490-D494 VanDerWaalsContact O-N 3.13Å; L491-D494 PolarHBondContact O-N 3.39Å
495M83.6Confident86.7Confident82 Ų8281.3 Ų81.340%0.40444%0.435SS..  trans-74.9148.7176.2-64.8177.6173.500111.1A490 L493 A497A490-M495 HydrophobicContact CB-CB 4.07Å; A490-M495 HydrophobicContact CB-SD 4.4Å; A490-M495 PolarHBondContact O-N 3.22Å; L493-M495 HydrophobicContact CB-CE 3.99Å; L493-M495 HydrophobicContact CB-CG 4.01Å; L493-M495 HydrophobicContact CB-SD 4.42Å; L493-M495 HydrophobicContact CD1-CE 3.5Å; L493-M495 HydrophobicContact CG-CE 4.39Å; L493-M495 PolarHBondContact O-N 2.79Å; M495-A497 VanDerWaalsContact C-N 3.34Å; M495-A497 PolarHBondContact O-N 3.01Å
496L83.1Confident86.9Confident188 Ų18885.8 Ų85.898%0.98446%0.458SS*.SBendtrans-66.7-34179.3-69.8172.4000113.2
497A84.4Confident87.1Confident67 Ų6787.4 Ų87.455%0.55448%0.475SS*.SBendtrans-151.6148.7178.300000110M495M495-A497 VanDerWaalsContact C-N 3.34Å; M495-A497 PolarHBondContact O-N 3.01Å
498P85.9Confident87.3Confident50 Ų5090 Ų9033%0.32548%0.483SS..PPolyproline II helixtrans-67.4152.6170.330.8-34.8000111.1N487 A490N487-P498 WeakPolarHBondContact OD1-CB 3.46Å; N487-P498 WeakPolarHBondContact OD1-CG 3.35Å; A490-P498 HydrophobicContact CB-CB 3.93Å
499E82.4Confident87.5Confident108 Ų10890 Ų9051%0.50549%0.487SS..PPolyproline II helixtrans-65.3139.1170.2-64.1179.5153.500110.4R486R486-E499 IonicContact CZ-OE2 3.12Å; R486-E499 IonicContact NH1-OE2 2.85Å; R486-E499 PolarHBondContact NH1-OE2 2.82Å; R486-E499 VanDerWaalsContact NH1-OE2 3.08Å
500D85.7Confident87.9Confident163 Ų16394.2 Ų94.287%0.87251%0.51SS*.PPolyproline II helixtrans-67.8140172.9-69.4-38.3000110.4
501I87.5Confident88.1Confident51 Ų5199.7 Ų99.726%0.26254%0.535SS..  trans-105.9144.1175.965172.1000110.7P479 Q482 Q483 R486P479-I501 WeakPolarHBondContact O-CD1 3.48Å; Q482-I501 HydrophobicContact CB-CD1 3.91Å; Q482-I501 HydrophobicContact CB-CG2 4.48Å; Q483-I501 HydrophobicContact CB-CD1 3.76Å; R486-I501 HydrophobicContact CG-CG2 3.8Å
502E87.4Confident88.4Confident139 Ų13996.2 Ų96.265%0.6552%0.517SS*.  trans-82.5126.8168.2-172.8-178.1172.600109.6L504E502-L504 HydrophobicContact CG-CD2 4.25Å; E502-L504 PolarHBondContact O-N 2.86Å
503D90.4Very high88.8Confident60 Ų6097.9 Ų97.932%0.32152%0.518SS..  trans-81.497175-169.7-7.9000111.2I505 M506D503-I505 PolarHBondContact O-N 2.95Å; D503-I505 WeakPolarHBondContact OD1-CG1 3.39Å; D503-I505 PolarHBondContact OD1-N 2.84Å; D503-I505 VanDerWaalsContact OD1-N 3.08Å; D503-M506 HydrophobicContact CB-CG 3.97Å; D503-M506 PolarHBondContact O-N 2.87Å; D503-M506 WeakPolarHBondContact OD2-CG 3.35Å
504L90.4Very high89.4Confident69 Ų69104.2 Ų104.236%0.36155%0.547SS..THydrogen-bonded Turntrans-69.2-15.1-178-59.4177.7000114.1F476 E477 E502F476-L504 HydrophobicContact CD1-CB 4.49Å; F476-L504 WeakPolarHBondContact CD1-O 3.22Å; E477-L504 HydrophobicContact CG-CD1 4.42Å; E502-L504 HydrophobicContact CG-CD2 4.25Å; E502-L504 PolarHBondContact O-N 2.86Å
505I92.7Very high89.8Confident100 Ų100103.6 Ų103.651%0.51353%0.533SS..THydrogen-bonded Turntrans-84.9-13.8177.161155.9000112.6F476 P479 D503F476-I505 HydrophobicContact CB-CG2 4.41Å; F476-I505 HydrophobicContact CD1-CG2 4.41Å; P479-I505 HydrophobicContact CG-CD1 4.01Å; P479-I505 HydrophobicContact CG-CG1 4.07Å; D503-I505 PolarHBondContact O-N 2.95Å; D503-I505 WeakPolarHBondContact OD1-CG1 3.39Å; D503-I505 PolarHBondContact OD1-N 2.84Å; D503-I505 VanDerWaalsContact OD1-N 3.08Å
506M92.8Very high90.2Very high120 Ų120100.2 Ų100.259%0.59152%0.516SS*.SBendtrans-73.8130.8177.2-71.5-62.8-6700110.9D503 K508D503-M506 HydrophobicContact CB-CG 3.97Å; D503-M506 PolarHBondContact O-N 2.87Å; D503-M506 WeakPolarHBondContact OD2-CG 3.35Å; M506-K508 PolarHBondContact O-N 2.87Å
507P93.3Very high90.6Very high85 Ų8593 Ų9355%0.55249%0.487SS*.  trans-61138.3175.6-21.432.2000111.1V509 I512P507-V509 HydrophobicContact CB-CG2 4.48Å; P507-V509 PolarHBondContact O-N 2.83Å; P507-I512 HydrophobicContact CB-CD1 3.9Å
508K93.4Very high91Very high115 Ų11593.7 Ų93.750%0.549%0.486SS..  trans-76.871.9174-60.2-173.7-179.9-169.90110.2M506 D510 Q511 I512M506-K508 PolarHBondContact O-N 2.87Å; K508-D510 PolarHBondContact O-N 3.47Å; K508-Q511 HydrophobicContact CB-CB 4.1Å; K508-Q511 HydrophobicContact CB-CG 4.19Å; K508-Q511 PolarHBondContact O-N 2.79Å; K508-I512 WeakPolarHBondContact O-CG1 3.32Å; K508-I512 PolarHBondContact O-N 2.84Å
509V93.7Very high91.3Very high81 Ų8192.1 Ų92.149%0.49148%0.475SS..Hα-helixtrans-50.7-51-170.2-179.60000111.9P507 Q511 I512 D513P507-V509 HydrophobicContact CB-CG2 4.48Å; P507-V509 PolarHBondContact O-N 2.83Å; V509-Q511 VanDerWaalsContact C-N 3.28Å; V509-Q511 PolarHBondContact O-N 3.37Å; V509-I512 WeakPolarHBondContact O-CA 3.2Å; V509-I512 WeakPolarHBondContact O-CB 3.48Å; V509-I512 PolarHBondContact O-N 2.77Å; V509-D513 PolarHBondContact O-N 3.5Å
510D93.1Very high91.7Very high126 Ų12689 Ų8967%0.67446%0.463SS*.Hα-helixtrans-58.9-39.6-179-59.3-30.9000112.7K508 Q514K508-D510 PolarHBondContact O-N 3.47Å; D510-Q514 WeakPolarHBondContact O-CB 3.41Å; D510-Q514 WeakPolarHBondContact O-CG 3.21Å; D510-Q514 PolarHBondContact O-N 2.92Å
511Q91.8Very high91.9Very high122 Ų12285.3 Ų85.357%0.5744%0.443SS*.Hα-helixtrans-71.5-36.5177.9-60.9-175.116.900111.5K508 V509 R515K508-Q511 HydrophobicContact CB-CB 4.1Å; K508-Q511 HydrophobicContact CB-CG 4.19Å; K508-Q511 PolarHBondContact O-N 2.79Å; V509-Q511 VanDerWaalsContact C-N 3.28Å; V509-Q511 PolarHBondContact O-N 3.37Å; Q511-R515 VanDerWaalsContact O-CB 3.24Å; Q511-R515 WeakPolarHBondContact O-CB 3.46Å; Q511-R515 PolarHBondContact O-N 2.77Å
512I94.3Very high92.1Very high55 Ų5586.3 Ų86.328%0.28245%0.447SS..Hα-helixtrans-63.9-48.9176.2-70.3168.1000109.5L467 P507 K508 V509 R515 L516L467-I512 HydrophobicContact CD2-CB 4.48Å; L467-I512 HydrophobicContact CD2-CG1 4.34Å; L467-I512 HydrophobicContact CD2-CG2 3.95Å; P507-I512 HydrophobicContact CB-CD1 3.9Å; K508-I512 WeakPolarHBondContact O-CG1 3.32Å; K508-I512 PolarHBondContact O-N 2.84Å; V509-I512 WeakPolarHBondContact O-CA 3.2Å; V509-I512 WeakPolarHBondContact O-CB 3.48Å; V509-I512 PolarHBondContact O-N 2.77Å; I512-R515 PolarHBondContact O-N 2.87Å; I512-L516 HydrophobicContact CG2-CD1 3.65Å; I512-L516 HydrophobicContact CG2-CG 4.37Å; I512-L516 WeakPolarHBondContact O-CB 3.5Å; I512-L516 VanDerWaalsContact O-CG 3.26Å; I512-L516 WeakPolarHBondContact O-CG 3.39Å; I512-L516 PolarHBondContact O-N 3.15Å
513D93.3Very high92.4Very high90 Ų9081.6 Ų81.648%0.48142%0.424SS..Hα-helixtrans-63.6-45.8-178.7-72.4-15.5000111.6V509 R515 L516 G517V509-D513 PolarHBondContact O-N 3.5Å; D513-R515 VanDerWaalsContact C-N 3.3Å; D513-R515 PolarHBondContact O-N 3.25Å; D513-L516 PolarHBondContact O-N 2.83Å; D513-G517 PolarHBondContact O-N 3.49Å
514Q93.1Very high92.4Very high163 Ų16382.9 Ų82.976%0.76243%0.427SS*.Hα-helixtrans-59.7-40.2174.9-74.5176.316.400112.4D510D510-Q514 WeakPolarHBondContact O-CB 3.41Å; D510-Q514 WeakPolarHBondContact O-CG 3.21Å; D510-Q514 PolarHBondContact O-N 2.92Å
515R92.9Very high92.4Very high141 Ų14186.1 Ų86.153%0.53245%0.445SS..Hα-helixtrans-70.9-40.7-178.7-162.8169.7-166.9-167.4-6111.4K466 Q511 I512 D513K466-R515 WeakPolarHBondContact CD-O 3.49Å; K466-R515 PolarHBondContact NZ-O 2.84Å; K466-R515 VanDerWaalsContact O-CD 3.22Å; K466-R515 WeakPolarHBondContact O-CD 3.47Å; K466-R515 PolarHBondContact O-NE 2.87Å; K466-R515 PolarHBondContact O-NH1 2.87Å; K466-R515 VanDerWaalsContact O-NH1 3.17Å; K466-R515 PolarHBondContact O-NH2 2.91Å; Q511-R515 VanDerWaalsContact O-CB 3.24Å; Q511-R515 WeakPolarHBondContact O-CB 3.46Å; Q511-R515 PolarHBondContact O-N 2.77Å; I512-R515 PolarHBondContact O-N 2.87Å; D513-R515 VanDerWaalsContact C-N 3.3Å; D513-R515 PolarHBondContact O-N 3.25Å
516L92.5Very high92.3Very high11 Ų1184.8 Ų84.86%0.05844%0.438CS..Hα-helixtrans-73.9-42.4-177.9-68.4173.9000112.4I463 K466 L467 I512 D513 L519 V520I463-L516 HydrophobicContact CB-CD2 4.34Å; I463-L516 HydrophobicContact CG1-CD2 4.38Å; I463-L516 HydrophobicContact CG2-CD2 3.89Å; K466-L516 HydrophobicContact CB-CD2 4.18Å; K466-L516 PolarHBondContact NZ-O 2.87Å; L467-L516 HydrophobicContact CD1-CD1 4.16Å; L467-L516 HydrophobicContact CD1-CD2 4.15Å; L467-L516 HydrophobicContact CD2-CD1 4.23Å; L467-L516 HydrophobicContact CD2-CD2 3.93Å; L467-L516 HydrophobicContact CD2-CG 3.97Å; L467-L516 HydrophobicContact CG-CD2 3.85Å; L467-L516 HydrophobicContact CG-CG 4.37Å; I512-L516 HydrophobicContact CG2-CD1 3.65Å; I512-L516 HydrophobicContact CG2-CG 4.37Å; I512-L516 WeakPolarHBondContact O-CB 3.5Å; I512-L516 VanDerWaalsContact O-CG 3.26Å; I512-L516 WeakPolarHBondContact O-CG 3.39Å; I512-L516 PolarHBondContact O-N 3.15Å; D513-L516 PolarHBondContact O-N 2.83Å; L516-L519 PolarHBondContact O-N 2.79Å; L516-V520 HydrophobicContact CB-CG2 3.73Å; L516-V520 HydrophobicContact CD1-CG2 3.66Å; L516-V520 HydrophobicContact CG-CG2 4.29Å
517G90.9Very high92.2Very high36 Ų3681.7 Ų81.737%0.37143%0.426SS..THydrogen-bonded Turntrans57.7-133-178.500000111.9D513 L519D513-G517 PolarHBondContact O-N 3.49Å; G517-L519 PolarHBondContact O-N 2.98Å
518P92.9Very high92Very high82 Ų8282.4 Ų82.453%0.53242%0.418SS..THydrogen-bonded Turntrans-71.7-12.5-173.930.6-36.3000114.2V520 D521 E522P518-V520 PolarHBondContact O-N 3.45Å; P518-V520 VanDerWaalsContact O-N 3.14Å; P518-D521 PolarHBondContact O-N 3.15Å; P518-E522 WeakPolarHBondContact O-CG 3.45Å; P518-E522 PolarHBondContact O-N 3.14Å
519L92.3Very high91.6Very high17 Ų1781.2 Ų81.29%0.08942%0.422CS..Hα-helixtrans-59-30.5-176.9-70.2177000113.1E462 I463 K466 L516 G517 F523E462-L519 HydrophobicContact CB-CD1 4.41Å; E462-L519 WeakPolarHBondContact OE2-CD2 3.32Å; I463-L519 HydrophobicContact CG1-CB 4.19Å; K466-L519 HydrophobicContact CD-CD1 3.71Å; K466-L519 VanDerWaalsContact CE-CD1 3.45Å; K466-L519 HydrophobicContact CG-CD1 4.38Å; L516-L519 PolarHBondContact O-N 2.79Å; G517-L519 PolarHBondContact O-N 2.98Å; L519-F523 VanDerWaalsContact O-CB 3.31Å; L519-F523 WeakPolarHBondContact O-CB 3.34Å; L519-F523 PolarHBondContact O-N 3.03Å
520V91.2Very high91.1Very high42 Ų4282.6 Ų82.626%0.25544%0.442SS..Hα-helixtrans-65.8-45.9177.4177.70000110.2L516 P518 F523 K524L516-V520 HydrophobicContact CB-CG2 3.73Å; L516-V520 HydrophobicContact CD1-CG2 3.66Å; L516-V520 HydrophobicContact CG-CG2 4.29Å; P518-V520 PolarHBondContact O-N 3.45Å; P518-V520 VanDerWaalsContact O-N 3.14Å; V520-F523 PolarHBondContact O-N 2.73Å; V520-K524 HydrophobicContact CG1-CD 4.32Å; V520-K524 VanDerWaalsContact O-CG 3.3Å; V520-K524 WeakPolarHBondContact O-CG 3.23Å; V520-K524 PolarHBondContact O-N 3.29Å
521D90.6Very high90.3Very high86 Ų8680.7 Ų80.746%0.4645%0.452SS..Hα-helixtrans-73.6-38.9-177.5-61.4-34000111P518 F523 K524 D525P518-D521 PolarHBondContact O-N 3.15Å; D521-F523 VanDerWaalsContact C-N 3.28Å; D521-F523 PolarHBondContact O-N 3.26Å; D521-K524 WeakPolarHBondContact O-CB 3.44Å; D521-K524 PolarHBondContact O-N 2.93Å; D521-K524 IonicContact OD1-NZ 2.96Å; D521-K524 PolarHBondContact OD1-NZ 2.93Å; D521-D525 PolarHBondContact O-N 3.46Å
522E91.6Very high89.8Confident73 Ų7381.2 Ų81.234%0.34145%0.45SS..Hα-helixtrans-57.4-40.8170-69.9175.6-154.500112.3K459 P518 L526K459-E522 VanDerWaalsContact CE-OE2 3.23Å; K459-E522 WeakPolarHBondContact CE-OE2 3.48Å; K459-E522 IonicContact NZ-OE2 3.64Å; K459-E522 PolarHBondContact NZ-OE2 3.25Å; P518-E522 WeakPolarHBondContact O-CG 3.45Å; P518-E522 PolarHBondContact O-N 3.14Å; E522-L526 VanDerWaalsContact O-CG 3.27Å; E522-L526 WeakPolarHBondContact O-CG 3.44Å; E522-L526 PolarHBondContact O-N 2.93Å
523F93.4Very high89Confident40 Ų4082.4 Ų82.418%0.17546%0.457CS..Hα-helixtrans-71.1-39.1177.2-176.9-100.3000112.1K459 M460 I463 L519 V520 D521 L526 V527K459-F523 HydrophobicContact CB-CD2 4.03Å; M460-F523 HydrophobicContact CB-CE2 3.97Å; M460-F523 HydrophobicContact CB-CZ 4.5Å; M460-F523 HydrophobicContact CE-CD1 4.08Å; M460-F523 HydrophobicContact CE-CD2 4.33Å; M460-F523 HydrophobicContact CE-CE1 3.46Å; M460-F523 VanDerWaalsContact CE-CE1 3.46Å; M460-F523 HydrophobicContact CE-CE2 3.76Å; M460-F523 HydrophobicContact CE-CG 4.48Å; M460-F523 HydrophobicContact CE-CZ 3.27Å; I463-F523 HydrophobicContact CD1-CB 3.84Å; I463-F523 HydrophobicContact CD1-CD2 4.44Å; I463-F523 HydrophobicContact CD1-CG 4.01Å; L519-F523 VanDerWaalsContact O-CB 3.31Å; L519-F523 WeakPolarHBondContact O-CB 3.34Å; L519-F523 PolarHBondContact O-N 3.03Å; V520-F523 PolarHBondContact O-N 2.73Å; D521-F523 VanDerWaalsContact C-N 3.28Å; D521-F523 PolarHBondContact O-N 3.26Å; F523-L526 PolarHBondContact O-N 3.41Å; F523-V527 HydrophobicContact CD1-CG2 4.39Å; F523-V527 HydrophobicContact CD2-CG2 4.28Å; F523-V527 HydrophobicContact CE1-CG2 3.93Å; F523-V527 HydrophobicContact CE2-CG2 3.81Å; F523-V527 HydrophobicContact CZ-CG2 3.62Å; F523-V527 WeakPolarHBondContact O-CG2 3.45Å; F523-V527 PolarHBondContact O-N 3.2Å
524K90.9Very high88.1Confident87 Ų8781.9 Ų81.938%0.37846%0.458SS..Hα-helixtrans-59.5-46.9173.9-74.2170.6-172156.80110.7V520 D521 L526 V527 Y528V520-K524 HydrophobicContact CG1-CD 4.32Å; V520-K524 VanDerWaalsContact O-CG 3.3Å; V520-K524 WeakPolarHBondContact O-CG 3.23Å; V520-K524 PolarHBondContact O-N 3.29Å; D521-K524 WeakPolarHBondContact O-CB 3.44Å; D521-K524 PolarHBondContact O-N 2.93Å; D521-K524 IonicContact OD1-NZ 2.96Å; D521-K524 PolarHBondContact OD1-NZ 2.93Å; K524-L526 PolarHBondContact O-N 3.45Å; K524-V527 PolarHBondContact O-N 2.87Å; K524-V527 VanDerWaalsContact O-N 3.12Å; K524-Y528 HydrophobicContact CB-CD2 4.1Å; K524-Y528 HydrophobicContact CG-CD2 3.95Å; K524-Y528 HydrophobicContact CG-CE2 4.11Å; K524-Y528 WeakPolarHBondContact O-CB 3.36Å; K524-Y528 PolarHBondContact O-N 3.11Å
525D90.4Very high87.3Confident137 Ų13782.2 Ų82.273%0.73346%0.46SS*.Hα-helixtrans-61.7-30.8180-71.2-16.6000112.7D521D521-D525 PolarHBondContact O-N 3.46Å
526L89.8Confident86.1Confident71 Ų7179.9 Ų79.937%0.37246%0.461SS..Hα-helixtrans-79.4-22.7177.6-71.9171.5000114.1T455 Q456 K459 E522 F523 K524T455-L526 HydrophobicContact CG2-CD1 4.28Å; T455-L526 HydrophobicContact CG2-CD2 4.36Å; Q456-L526 HydrophobicContact CG-CB 4.18Å; Q456-L526 PolarHBondContact NE2-O 3.34Å; K459-L526 HydrophobicContact CB-CD1 4.26Å; K459-L526 HydrophobicContact CG-CD1 3.61Å; E522-L526 VanDerWaalsContact O-CG 3.27Å; E522-L526 WeakPolarHBondContact O-CG 3.44Å; E522-L526 PolarHBondContact O-N 2.93Å; F523-L526 PolarHBondContact O-N 3.41Å; K524-L526 PolarHBondContact O-N 3.45Å
527V89.9Confident84.1Confident55 Ų5588.6 Ų88.633%0.33350%0.499SS..Hα-helixtrans-115.3-44.4-170177.10000112.4Q456 F523 K524Q456-V527 HydrophobicContact CB-CG2 4.46Å; Q456-V527 HydrophobicContact CG-CG2 3.92Å; F523-V527 HydrophobicContact CD1-CG2 4.39Å; F523-V527 HydrophobicContact CD2-CG2 4.28Å; F523-V527 HydrophobicContact CE1-CG2 3.93Å; F523-V527 HydrophobicContact CE2-CG2 3.81Å; F523-V527 HydrophobicContact CZ-CG2 3.62Å; F523-V527 WeakPolarHBondContact O-CG2 3.45Å; F523-V527 PolarHBondContact O-N 3.2Å; K524-V527 PolarHBondContact O-N 2.87Å; K524-V527 VanDerWaalsContact O-N 3.12Å
528Y89.1Confident82.3Confident101 Ų10192.7 Ų92.740%0.39652%0.519SS..SBendtrans-90.8125.8-176-63.7-32.1000110.8K524 Y532K524-Y528 HydrophobicContact CB-CD2 4.1Å; K524-Y528 HydrophobicContact CG-CD2 3.95Å; K524-Y528 HydrophobicContact CG-CE2 4.11Å; K524-Y528 WeakPolarHBondContact O-CB 3.36Å; K524-Y528 PolarHBondContact O-N 3.11Å; Y528-Y532 AromaticContact CD1-CD1 3.63Å; Y528-Y532 HydrophobicContact CD1-CD1 3.63Å; Y528-Y532 AromaticContact CD1-CE1 3.66Å; Y528-Y532 HydrophobicContact CD1-CE1 3.66Å; Y528-Y532 HydrophobicContact CD2-CD1 4.45Å; Y528-Y532 HydrophobicContact CE1-CD1 4.25Å; Y528-Y532 AromaticContact CE1-CE1 3.85Å; Y528-Y532 HydrophobicContact CE1-CE1 3.85Å; Y528-Y532 AromaticContact CG-CD1 3.76Å; Y528-Y532 HydrophobicContact CG-CD1 3.76Å; Y528-Y532 HydrophobicContact CG-CE1 4.21Å
529P86.2Confident80Confident89 Ų8993 Ų9358%0.57853%0.528SS*.PPolyproline II helixtrans-60150.7172.3-22.933.4000111.9G531 Y532P529-G531 PolarHBondContact O-N 2.91Å; P529-Y532 WeakPolarHBondContact O-CB 3.32Å; P529-Y532 PolarHBondContact O-N 3.04Å
530A82.3Confident77.7Confident111 Ų11197.9 Ų97.992%0.91756%0.561SS**THydrogen-bonded Turntrans-55.5127.7174.700000111.1Y532A530-Y532 VanDerWaalsContact C-N 3.34Å
531G76.6Confident75.4Confident86 Ų86105.5 Ų105.589%0.88759%0.591SS**THydrogen-bonded Turntrans82.53.4-176.700000115.3P529 N533P529-G531 PolarHBondContact O-N 2.91Å; G531-N533 PolarHBondContact O-N 3.34Å
532Y81.4Confident72.8Confident133 Ų133112.8 Ų112.852%0.52261%0.612SS.*  trans-72.6115.8171.3-177.3-103.8000110.5Y528 P529 A530 P534Y528-Y532 AromaticContact CD1-CD1 3.63Å; Y528-Y532 HydrophobicContact CD1-CD1 3.63Å; Y528-Y532 AromaticContact CD1-CE1 3.66Å; Y528-Y532 HydrophobicContact CD1-CE1 3.66Å; Y528-Y532 HydrophobicContact CD2-CD1 4.45Å; Y528-Y532 HydrophobicContact CE1-CD1 4.25Å; Y528-Y532 AromaticContact CE1-CE1 3.85Å; Y528-Y532 HydrophobicContact CE1-CE1 3.85Å; Y528-Y532 AromaticContact CG-CD1 3.76Å; Y528-Y532 HydrophobicContact CG-CD1 3.76Å; Y528-Y532 HydrophobicContact CG-CE1 4.21Å; P529-Y532 WeakPolarHBondContact O-CB 3.32Å; P529-Y532 PolarHBondContact O-N 3.04Å; A530-Y532 VanDerWaalsContact C-N 3.34Å; Y532-P534 HydrophobicContact CE1-CB 4Å
533N77.3Confident70.1Confident79 Ų79119 Ų11942%0.42264%0.638SS.*  trans-102.9109.2171.2-174.7-9.4000109.7G531 E535 T536G531-N533 PolarHBondContact O-N 3.34Å; N533-E535 PolarHBondContact O-N 3.41Å; N533-E535 VanDerWaalsContact O-N 3.11Å; N533-E535 PolarHBondContact OD1-N 2.99Å; N533-T536 HydrophobicContact CB-CG2 4.05Å; N533-T536 PolarHBondContact O-N 3.44Å; N533-T536 VanDerWaalsContact O-N 3.16Å; N533-T536 PolarHBondContact O-OG1 3.25Å
534P73.8Confident67.1Low79 Ų79123.5 Ų123.551%0.51367%0.669SS.*THydrogen-bonded Turntrans-63.1-17.1-179.725.8-33.4000113.6Y532Y532-P534 HydrophobicContact CE1-CB 4Å
535E76.8Confident64.3Low170 Ų170123.9 Ų123.979%0.79469%0.688SS**THydrogen-bonded Turntrans-92-10179.6-57.9-161.5158.800113.9N533 K537N533-E535 PolarHBondContact O-N 3.41Å; N533-E535 VanDerWaalsContact O-N 3.11Å; N533-E535 PolarHBondContact OD1-N 2.99Å; E535-K537 PolarHBondContact O-N 2.97Å; E535-K537 VanDerWaalsContact O-N 3.08Å
536T68.8Low61.5Low92 Ų92125.6 Ų125.656%0.56470%0.697SS**SBendtrans-71.7105.8173.5420000110.4N533N533-T536 HydrophobicContact CB-CG2 4.05Å; N533-T536 PolarHBondContact O-N 3.44Å; N533-T536 VanDerWaalsContact O-N 3.16Å; N533-T536 PolarHBondContact O-OG1 3.25Å
537K50.3Low58.6Low195 Ų195125.5 Ų125.585%0.84871%0.714SS**PPolyproline II helixtrans-54.7127.9171.6-79.1-179.5179.1173.70109.3E535 A539E535-K537 PolarHBondContact O-N 2.97Å; E535-K537 VanDerWaalsContact O-N 3.08Å; K537-A539 PolarHBondContact O-N 3.01Å
538P51.9Low55.6Low122 Ų122126.8 Ų126.879%0.79274%0.738SS**PPolyproline II helixtrans-59130.7172.722.4-29.8000108.7
539A45.1Very low52.7Low87 Ų87126.7 Ų126.772%0.71976%0.758SS**PPolyproline II helixtrans-52.5135.4179.100000109.4K537 K541K537-A539 PolarHBondContact O-N 3.01Å; A539-K541 PolarHBondContact O-N 3.42Å
540P44.9Very low50Low120 Ų120126 Ų12678%0.77977%0.767SS**PPolyproline II helixtrans-56.2120.4179.222.2-30.9000107.8R542P540-R542 PolarHBondContact O-N 3.09Å
541K42.4Very low47.4Very low203 Ų203125.8 Ų125.888%0.88377%0.765SS**  trans-50.4110.8167.9-85-176.3175.1174.80105.9A539 K543A539-K541 PolarHBondContact O-N 3.42Å; K541-K543 PolarHBondContact O-N 3.45Å
542R36Very low45.2Very low239 Ų239130.7 Ų130.790%0.90277%0.765SS**  trans-47.3112176.4-88.9177.4166170.1-4.7107.4P540 T544P540-R542 PolarHBondContact O-N 3.09Å; R542-T544 PolarHBondContact O-N 3.03Å
543K34.7Very low42.8Very low203 Ų203134.1 Ų134.188%0.88378%0.782SS**  trans-60.7107.7156.9-76.8-176.9176.1-179.60104.8K541 A545K541-K543 PolarHBondContact O-N 3.45Å; K543-A545 PolarHBondContact O-N 3.15Å
544T30.2Very low40.5Very low135 Ų135139.6 Ų139.683%0.82880%0.803SS**PPolyproline II helixtrans-55.7121.6163.136.90000106.8R542R542-T544 PolarHBondContact O-N 3.03Å
545A31.3Very low38.5Very low95 Ų95141.4 Ų141.479%0.78581%0.814SS**PPolyproline II helixtrans-55.8142.3-178.500000110.9K543 G547K543-A545 PolarHBondContact O-N 3.15Å; A545-G547 PolarHBondContact O-N 3.49Å
546D33.2Very low36.4Very low172 Ų172142.8 Ų142.892%0.9282%0.817SS**PPolyproline II helixtrans-59.3126.3171.2-145.3-2.6000109.3
547G27.6Very low35.2Very low70 Ų70145.1 Ų145.172%0.72283%0.832SS**  trans-159.690.3-178.300000108.5A545A545-G547 PolarHBondContact O-N 3.49Å
548G27.6Very low35Very low81 Ų81137.1 Ų137.184%0.83580%0.804SS**  trans-67.6128.3-177.500000113
549A29.2Very low35.3Very low100 Ų100132.4 Ų132.483%0.82678%0.775SS**SBendtrans175.2125.713900000109.2
550G29Very low36.2Very low74 Ų74131.7 Ų131.776%0.76376%0.762SS**  trans77.279.1163.200000116.6E552G550-E552 VanDerWaalsContact C-N 3.31Å; G550-E552 PolarHBondContact O-N 2.83Å
551A27.7Very low37.1Very low106 Ų106127.6 Ų127.688%0.87674%0.739SS**  trans-70.785.9165.300000110.7K553A551-K553 PolarHBondContact O-N 2.69Å
552E31.1Very low38.2Very low189 Ų189123.9 Ų123.988%0.88373%0.728SS**  trans-64.7119.5153.5-78.7-171.1154.600108.4G550 K554G550-E552 VanDerWaalsContact C-N 3.31Å; G550-E552 PolarHBondContact O-N 2.83Å; E552-K554 PolarHBondContact O-N 2.92Å
553K31.1Very low39.9Very low205 Ų205117.3 Ų117.389%0.89171%0.708SS**  trans-57.3105.3175.7-75.9173.9175.81710109.6A551A551-K553 PolarHBondContact O-N 2.69Å
554K28.4Very low41.5Very low195 Ų195107.8 Ų107.885%0.84867%0.666SS**PPolyproline II helixtrans-54.2131.9156.5-83.1-178.6175.4177.10108.2E552 K556E552-K554 PolarHBondContact O-N 2.92Å; K554-K556 PolarHBondContact O-N 2.93Å
555P30.7Very low43.4Very low116 Ų116106.1 Ų106.175%0.75365%0.648SS**PPolyproline II helixtrans-60.7138.4179.7-1324.6000109.8V557P555-V557 PolarHBondContact O-N 3.32Å; P555-V557 VanDerWaalsContact O-N 3.15Å
556K34Very low45.4Very low199 Ų199103.7 Ų103.787%0.86563%0.627SS**PPolyproline II helixtrans-51121.5168.1-89.8179.3170.1-178.80108.2K554 G558K554-K556 PolarHBondContact O-N 2.93Å; K556-G558 PolarHBondContact O-N 3.14Å
557V42.5Very low47.3Very low142 Ų14298.7 Ų98.786%0.86160%0.598SS**PPolyproline II helixtrans-49.4123.9169.7179.60000108.1P555P555-V557 PolarHBondContact O-N 3.32Å; P555-V557 VanDerWaalsContact O-N 3.15Å
558G47.3Very low49.3Very low26 Ų2697.4 Ų97.427%0.26857%0.574SS.*PPolyproline II helixtrans-55.2147-179.600000112.3K556 T560K556-G558 PolarHBondContact O-N 3.14Å; G558-T560 PolarHBondContact O-N 3.17Å
559A56.5Low51.4Low23 Ų23101.2 Ų101.219%0.1957%0.57CS.*PPolyproline II helixtrans-52.9134.8-179.800000111.1L564 V580 Q587A559-L564 HydrophobicContact CB-CD1 4.28Å; A559-L564 HydrophobicContact CB-CD2 4.22Å; A559-L564 HydrophobicContact CB-CG 3.97Å; A559-V580 HydrophobicContact CB-CG1 4.29Å; A559-Q587 PolarHBondContact O-OE1 3.27Å
560T64.1Low53.6Low73 Ų73102 Ų10245%0.44856%0.561SS.*PPolyproline II helixtrans-69.9155.2178.8550000110.9G558 D562 E563 L564G558-T560 PolarHBondContact O-N 3.17Å; T560-D562 PolarHBondContact O-N 2.87Å; T560-D562 VanDerWaalsContact O-N 3.14Å; T560-E563 PolarHBondContact N-OE2 2.84Å; T560-E563 PolarHBondContact O-N 2.89Å; T560-E563 VanDerWaalsContact O-N 3.09Å; T560-E563 VanDerWaalsContact OG1-CG 3.25Å; T560-E563 WeakPolarHBondContact OG1-CG 3.49Å; T560-E563 PolarHBondContact OG1-OE2 2.8Å; T560-L564 PolarHBondContact O-N 3.29Å; T560-L564 VanDerWaalsContact O-N 3.08Å
561A64.3Low55.7Low34 Ų34101.8 Ų101.828%0.28156%0.558SS.*Hα-helixtrans-56.7-31.9-17800000113.1K565 F588A561-K565 PolarHBondContact O-N 3.47Å; A561-K565 VanDerWaalsContact O-N 3.13Å; A561-F588 HydrophobicContact CB-CE1 4.37Å; A561-F588 HydrophobicContact CB-CZ 3.81Å
562D66.4Low58.1Low124 Ų12498.3 Ų98.366%0.66353%0.526SS*.Hα-helixtrans-74.9-36.8178.5-65-29.6000112.5T560 L564 K565 A566T560-D562 PolarHBondContact O-N 2.87Å; T560-D562 VanDerWaalsContact O-N 3.14Å; D562-L564 VanDerWaalsContact C-N 3.34Å; D562-K565 PolarHBondContact O-N 3.36Å; D562-A566 PolarHBondContact O-N 3.02Å
563E70.8Confident60.2Low101 Ų10189.8 Ų89.847%0.47249%0.487SS..Hα-helixtrans-65.7-38.7173.5-72.2168154.600111.3T560 A566 H567T560-E563 PolarHBondContact N-OE2 2.84Å; T560-E563 PolarHBondContact O-N 2.89Å; T560-E563 VanDerWaalsContact O-N 3.09Å; T560-E563 VanDerWaalsContact OG1-CG 3.25Å; T560-E563 WeakPolarHBondContact OG1-CG 3.49Å; T560-E563 PolarHBondContact OG1-OE2 2.8Å; E563-A566 PolarHBondContact O-N 2.95Å; E563-H567 WeakPolarHBondContact O-CB 3.45Å; E563-H567 PolarHBondContact O-CD2 2.88Å; E563-H567 PolarHBondContact O-N 2.83Å
564L69.4Low62.2Low3 Ų382.1 Ų82.12%0.01647%0.465CS..Hα-helixtrans-66.3-39.6176.2-73.3163.6000111.9A559 T560 D562 H567 M568 L576 A584 F588A559-L564 HydrophobicContact CB-CD1 4.28Å; A559-L564 HydrophobicContact CB-CD2 4.22Å; A559-L564 HydrophobicContact CB-CG 3.97Å; T560-L564 PolarHBondContact O-N 3.29Å; T560-L564 VanDerWaalsContact O-N 3.08Å; D562-L564 VanDerWaalsContact C-N 3.34Å; L564-H567 PolarHBondContact O-N 3.31Å; L564-M568 WeakPolarHBondContact O-CB 3.24Å; L564-M568 PolarHBondContact O-N 3.39Å; L564-L576 HydrophobicContact CD2-CD1 4.16Å; L564-A584 HydrophobicContact CD1-CB 3.56Å; L564-A584 HydrophobicContact CD2-CB 3.83Å; L564-A584 HydrophobicContact CG-CB 4.38Å; L564-F588 HydrophobicContact CD1-CE2 3.86Å
565K70.3Confident64.5Low101 Ų10181.2 Ų81.244%0.43946%0.461SS..Hα-helixtrans-64.4-40.7172.2-78.3-178.2178.1-178.80112.4A561 D562 M568 Q569A561-K565 PolarHBondContact O-N 3.47Å; A561-K565 VanDerWaalsContact O-N 3.13Å; D562-K565 PolarHBondContact O-N 3.36Å; K565-M568 WeakPolarHBondContact O-CB 3.39Å; K565-M568 PolarHBondContact O-N 2.88Å; K565-Q569 WeakPolarHBondContact O-CG 3.33Å; K565-Q569 PolarHBondContact O-N 3.09Å
566A72.7Confident66.7Low43 Ų4377 Ų7736%0.35543%0.432SS..Hα-helixtrans-65.6-40.1176.100000112.2D562 E563 M568 N570D562-A566 PolarHBondContact O-N 3.02Å; E563-A566 PolarHBondContact O-N 2.95Å; A566-M568 VanDerWaalsContact C-N 3.28Å; A566-M568 PolarHBondContact O-N 2.79Å; A566-N570 WeakPolarHBondContact O-CB 3.43Å; A566-N570 VanDerWaalsContact O-CG 3.31Å; A566-N570 PolarHBondContact O-N 3.16Å; A566-N570 VanDerWaalsContact O-N 3.09Å; A566-N570 PolarHBondContact O-ND2 3.13Å; A566-N570 VanDerWaalsContact O-ND2 3.15Å
567H73.4Confident68.9Low67 Ų6771.3 Ų71.331%0.3141%0.414SS..Hα-helixtrans-65.9-31174-80.9-61.2000113.1E563 L564 G571 T572 L573E563-H567 WeakPolarHBondContact O-CB 3.45Å; E563-H567 PolarHBondContact O-CD2 2.88Å; E563-H567 PolarHBondContact O-N 2.83Å; L564-H567 PolarHBondContact O-N 3.31Å; H567-G571 PolarHBondContact O-N 3.48Å; H567-T572 PolarHBondContact ND1-OG1 3.33Å; H567-T572 PolarHBondContact O-N 3.49Å; H567-T572 PolarHBondContact O-OG1 3Å; H567-L573 HydrophobicContact CB-CG 4.46Å; H567-L573 PolarHBondContact O-N 3.28Å
568M69.3Low70.6Confident43 Ų4366.9 Ų66.921%0.21239%0.388CS..Hα-helixtrans-70.3-50.6174.7-166.9176.376.700112.1L564 K565 A566 N570 G571 L573 N605 L608L564-M568 WeakPolarHBondContact O-CB 3.24Å; L564-M568 PolarHBondContact O-N 3.39Å; K565-M568 WeakPolarHBondContact O-CB 3.39Å; K565-M568 PolarHBondContact O-N 2.88Å; A566-M568 VanDerWaalsContact C-N 3.28Å; A566-M568 PolarHBondContact O-N 2.79Å; M568-N570 VanDerWaalsContact C-N 3.25Å; M568-N570 PolarHBondContact O-N 3.45Å; M568-G571 PolarHBondContact O-N 3.02Å; M568-G571 VanDerWaalsContact O-N 3.1Å; M568-L573 HydrophobicContact CB-CD1 3.68Å; M568-L573 HydrophobicContact CG-CD1 3.7Å; M568-N605 WeakPolarHBondContact CG-OD1 3.06Å; M568-L608 HydrophobicContact CE-CB 3.89Å; M568-L608 WeakPolarHBondContact CE-O 3.45Å; M568-L608 HydrophobicContact SD-CB 3.61Å
569Q71.8Confident71.9Confident162 Ų16270.5 Ų70.576%0.75740%0.404SS*.Hα-helixtrans-60.6-35.3178-72.6179.9-8.100112.7K565 G571K565-Q569 WeakPolarHBondContact O-CG 3.33Å; K565-Q569 PolarHBondContact O-N 3.09Å; Q569-G571 VanDerWaalsContact C-N 3.33Å
570N73.9Confident72.9Confident117 Ų11771.3 Ų71.363%0.62641%0.407SS*.THydrogen-bonded Turntrans-87.53.6-180-65.7-29.6000113.7A566 M568 T572A566-N570 WeakPolarHBondContact O-CB 3.43Å; A566-N570 VanDerWaalsContact O-CG 3.31Å; A566-N570 PolarHBondContact O-N 3.16Å; A566-N570 VanDerWaalsContact O-N 3.09Å; A566-N570 PolarHBondContact O-ND2 3.13Å; A566-N570 VanDerWaalsContact O-ND2 3.15Å; M568-N570 VanDerWaalsContact C-N 3.25Å; M568-N570 PolarHBondContact O-N 3.45Å; N570-T572 HydrophobicContact CB-CG2 4.42Å; N570-T572 PolarHBondContact O-N 3.19Å
571G74.1Confident73.5Confident68 Ų6867.9 Ų67.970%0.70139%0.386SS*.THydrogen-bonded Turntrans6322.9-179.700000114.5H567 M568 Q569H567-G571 PolarHBondContact O-N 3.48Å; M568-G571 PolarHBondContact O-N 3.02Å; M568-G571 VanDerWaalsContact O-N 3.1Å; Q569-G571 VanDerWaalsContact C-N 3.33Å
572T78.5Confident74Confident34 Ų3470.7 Ų70.721%0.20939%0.392CS..  trans-103.24.5-173.552.90000114.4H567 N570 G574 K575H567-T572 PolarHBondContact ND1-OG1 3.33Å; H567-T572 PolarHBondContact O-N 3.49Å; H567-T572 PolarHBondContact O-OG1 3Å; N570-T572 HydrophobicContact CB-CG2 4.42Å; N570-T572 PolarHBondContact O-N 3.19Å; T572-G574 PolarHBondContact O-N 2.87Å; T572-G574 VanDerWaalsContact O-N 3.12Å; T572-K575 HydrophobicContact CG2-CD 4.36Å; T572-K575 WeakPolarHBondContact O-CB 3.48Å; T572-K575 PolarHBondContact O-N 3.36Å
573L74.1Confident74.6Confident10 Ų1069.5 Ų69.55%0.05238%0.382CS..G310 helixtrans-49.9-35.6173-87.1155.9000113.2H567 M568 K575 L576 L581 I601 L604 N605H567-L573 HydrophobicContact CB-CG 4.46Å; H567-L573 PolarHBondContact O-N 3.28Å; M568-L573 HydrophobicContact CB-CD1 3.68Å; M568-L573 HydrophobicContact CG-CD1 3.7Å; L573-K575 PolarHBondContact O-N 3.08Å; L573-K575 VanDerWaalsContact O-N 3.13Å; L573-L576 HydrophobicContact CD2-CD1 4.22Å; L573-L576 PolarHBondContact O-N 3.43Å; L573-L576 VanDerWaalsContact O-N 3.12Å; L573-L581 HydrophobicContact CD2-CD2 3.94Å; L573-I601 HydrophobicContact CB-CG1 4.49Å; L573-I601 HydrophobicContact CB-CG2 4.2Å; L573-L604 HydrophobicContact CD2-CD1 4.48Å; L573-N605 WeakPolarHBondContact CD1-OD1 3.37Å
574G73.1Confident74.6Confident43 Ų4364.8 Ų64.844%0.44336%0.361SS..G310 helixtrans-62.7-15.7176.400000114.9T572 K597T572-G574 PolarHBondContact O-N 2.87Å; T572-G574 VanDerWaalsContact O-N 3.12Å; G574-K597 WeakPolarHBondContact O-CE 3.48Å; G574-K597 PolarHBondContact O-NZ 3.1Å
575K76.5Confident74.9Confident176 Ų17664.7 Ų64.777%0.76536%0.36SS*.G310 helixtrans-87.6-13177.3-62.2-176.3179.4178.30113.2T572 L573T572-K575 HydrophobicContact CG2-CD 4.36Å; T572-K575 WeakPolarHBondContact O-CB 3.48Å; T572-K575 PolarHBondContact O-N 3.36Å; L573-K575 PolarHBondContact O-N 3.08Å; L573-K575 VanDerWaalsContact O-N 3.13Å
576L78.2Confident75.2Confident28 Ų2868.2 Ų68.215%0.14738%0.376CS..SBendtrans-75.5151.4178.6-64.3172.7000111.5L564 L573 V580 L581 K597L564-L576 HydrophobicContact CD2-CD1 4.16Å; L573-L576 HydrophobicContact CD2-CD1 4.22Å; L573-L576 PolarHBondContact O-N 3.43Å; L573-L576 VanDerWaalsContact O-N 3.12Å; L576-V580 HydrophobicContact CD1-CG1 4.45Å; L576-V580 HydrophobicContact CD2-CG1 4.32Å; L576-L581 HydrophobicContact CB-CD2 4.19Å; L576-L581 HydrophobicContact CB-CG 4.1Å; L576-L581 HydrophobicContact CD1-CD2 4.19Å; L576-K597 WeakPolarHBondContact O-CE 3.48Å; L576-K597 PolarHBondContact O-NZ 3.13Å
577T79.4Confident75.4Confident79 Ų7971.5 Ų71.549%0.48538%0.384SS..  trans-74.5153.3175.759.30000110.4T579 V580 L581T577-T579 PolarHBondContact O-N 3.33Å; T577-T579 VanDerWaalsContact O-N 3.16Å; T577-T579 PolarHBondContact OG1-OG1 3.09Å; T577-V580 PolarHBondContact O-N 3.26Å; T577-V580 VanDerWaalsContact O-N 3.08Å; T577-V580 WeakPolarHBondContact OG1-CG2 3.42Å; T577-L581 PolarHBondContact O-N 3.36Å; T577-L581 VanDerWaalsContact O-N 3.09Å
578V77.8Confident75.3Confident50 Ų5070.9 Ų70.930%0.30338%0.38SS..Hα-helixtrans-57.3-31.6178.7178.70000111.8L581 K582 K597 L600V578-L581 PolarHBondContact O-N 2.98Å; V578-K582 HydrophobicContact CG1-CD 4.44Å; V578-K582 HydrophobicContact CG1-CG 4.48Å; V578-K582 WeakPolarHBondContact O-CG 3.23Å; V578-K582 PolarHBondContact O-N 3.49Å; V578-K597 HydrophobicContact CG2-CB 3.85Å; V578-K597 HydrophobicContact CG2-CD 3.97Å; V578-K597 HydrophobicContact CG2-CG 3.96Å; V578-L600 HydrophobicContact CG1-CD1 3.91Å
579T76Confident75.3Confident101 Ų10172 Ų7262%0.6240%0.402SS*.Hα-helixtrans-63.1-45.9175.545.10000112.8T577 K582 E583T577-T579 PolarHBondContact O-N 3.33Å; T577-T579 VanDerWaalsContact O-N 3.16Å; T577-T579 PolarHBondContact OG1-OG1 3.09Å; T579-K582 PolarHBondContact O-N 3.2Å; T579-E583 PolarHBondContact O-N 3.47Å; T579-E583 VanDerWaalsContact O-N 3.13Å
580V77.3Confident75.5Confident41 Ų4165.8 Ų65.825%0.24837%0.374CS..Hα-helixtrans-68.1-38.6178.3175.30000110.8A559 L576 T577 E583 A584A559-V580 HydrophobicContact CB-CG1 4.29Å; L576-V580 HydrophobicContact CD1-CG1 4.45Å; L576-V580 HydrophobicContact CD2-CG1 4.32Å; T577-V580 PolarHBondContact O-N 3.26Å; T577-V580 VanDerWaalsContact O-N 3.08Å; T577-V580 WeakPolarHBondContact OG1-CG2 3.42Å; V580-E583 PolarHBondContact O-N 3.09Å; V580-A584 WeakPolarHBondContact O-CB 3.24Å; V580-A584 PolarHBondContact O-N 3.16Å
581L75.6Confident75.1Confident0 Ų070.1 Ų70.10%039%0.387CS..Hα-helixtrans-65.9-39.7176.7-68.5168.5000112.3L573 L576 T577 V578 A584 C585 K597 L600 I601 L604L573-L581 HydrophobicContact CD2-CD2 3.94Å; L576-L581 HydrophobicContact CB-CD2 4.19Å; L576-L581 HydrophobicContact CB-CG 4.1Å; L576-L581 HydrophobicContact CD1-CD2 4.19Å; T577-L581 PolarHBondContact O-N 3.36Å; T577-L581 VanDerWaalsContact O-N 3.09Å; V578-L581 PolarHBondContact O-N 2.98Å; L581-A584 PolarHBondContact O-N 2.91Å; L581-C585 PolarHBondContact O-N 2.92Å; L581-C585 PolarHBondContact O-SG 3.25Å; L581-K597 HydrophobicContact CD1-CD 4.44Å; L581-K597 HydrophobicContact CD1-CG 3.78Å; L581-L600 HydrophobicContact CB-CB 4.12Å; L581-L600 HydrophobicContact CB-CD1 4.03Å; L581-I601 HydrophobicContact CD1-CD1 4.27Å; L581-I601 HydrophobicContact CD1-CG1 3.89Å; L581-I601 HydrophobicContact CD2-CG1 4.23Å; L581-L604 HydrophobicContact CD2-CD1 3.85Å
582K76.5Confident74.4Confident93 Ų9369.4 Ų69.440%0.40437%0.369SS..Hα-helixtrans-65.3-38.8174.6-75.6-174.5177.8-173.90112.5V578 T579 C585 K586 L600V578-K582 HydrophobicContact CG1-CD 4.44Å; V578-K582 HydrophobicContact CG1-CG 4.48Å; V578-K582 WeakPolarHBondContact O-CG 3.23Å; V578-K582 PolarHBondContact O-N 3.49Å; T579-K582 PolarHBondContact O-N 3.2Å; K582-C585 PolarHBondContact O-N 3.29Å; K582-K586 WeakPolarHBondContact O-CB 3.49Å; K582-K586 PolarHBondContact O-N 3.46Å; K582-L600 HydrophobicContact CG-CD1 3.62Å; K582-L600 HydrophobicContact CG-CD2 4.27Å
583E77Confident73.3Confident100 Ų10075 Ų7547%0.46740%0.404SS..Hα-helixtrans-68.9-40.1178.4-162.6163.6-160.800111.3T579 V580 K586 Q587T579-E583 PolarHBondContact O-N 3.47Å; T579-E583 VanDerWaalsContact O-N 3.13Å; V580-E583 PolarHBondContact O-N 3.09Å; E583-K586 WeakPolarHBondContact O-CB 3.37Å; E583-K586 PolarHBondContact O-N 3.37Å; E583-Q587 PolarHBondContact O-N 3.09Å
584A71.9Confident72.5Confident2 Ų275.5 Ų75.52%0.01741%0.411CS..Hα-helixtrans-59.7-48.6170.100000112.1L564 V580 L581 K586 Q587 F588 L604L564-A584 HydrophobicContact CD1-CB 3.56Å; L564-A584 HydrophobicContact CD2-CB 3.83Å; L564-A584 HydrophobicContact CG-CB 4.38Å; V580-A584 WeakPolarHBondContact O-CB 3.24Å; V580-A584 PolarHBondContact O-N 3.16Å; L581-A584 PolarHBondContact O-N 2.91Å; A584-K586 VanDerWaalsContact C-N 3.25Å; A584-K586 PolarHBondContact O-N 3.44Å; A584-Q587 WeakPolarHBondContact O-CB 3.47Å; A584-Q587 PolarHBondContact O-N 2.89Å; A584-Q587 VanDerWaalsContact O-N 3.14Å; A584-F588 WeakPolarHBondContact O-CD2 3.38Å; A584-F588 PolarHBondContact O-N 3.34Å; A584-F588 VanDerWaalsContact O-N 3.11Å; A584-L604 HydrophobicContact CB-CD1 4.04Å; A584-L604 HydrophobicContact CB-CD2 4.2Å
585C74.9Confident71.9Confident0 Ų079 Ų790%042%0.424CS..Hα-helixtrans-56.2-40.8175-71.40000112L581 K582 F588 G589 I590 T592L581-C585 PolarHBondContact O-N 2.92Å; L581-C585 PolarHBondContact O-SG 3.25Å; K582-C585 PolarHBondContact O-N 3.29Å; C585-F588 PolarHBondContact O-N 2.91Å; C585-G589 PolarHBondContact O-N 3.32Å; C585-I590 HydrophobicContact CB-CB 4.2Å; C585-I590 PolarHBondContact O-N 3.2Å; C585-T592 HydrophobicContact CB-CG2 3.99Å
586K77.8Confident71.9Confident176 Ų17677.4 Ų77.477%0.76542%0.417SS*.Hα-helixtrans-67-39.6178.1-165.8-179.4-179.3-1760111.9K582 E583 A584 F588 G589K582-K586 WeakPolarHBondContact O-CB 3.49Å; K582-K586 PolarHBondContact O-N 3.46Å; E583-K586 WeakPolarHBondContact O-CB 3.37Å; E583-K586 PolarHBondContact O-N 3.37Å; A584-K586 VanDerWaalsContact C-N 3.25Å; A584-K586 PolarHBondContact O-N 3.44Å; K586-F588 VanDerWaalsContact C-N 3.29Å; K586-F588 PolarHBondContact O-N 3.29Å; K586-G589 PolarHBondContact O-N 3.27Å
587Q75.7Confident71.8Confident112 Ų11279.5 Ų79.552%0.52343%0.425SS..Hα-helixtrans-64.1-34177.6-169.3175.89.100112.4A559 E583 A584A559-Q587 PolarHBondContact O-OE1 3.27Å; E583-Q587 PolarHBondContact O-N 3.09Å; A584-Q587 WeakPolarHBondContact O-CB 3.47Å; A584-Q587 PolarHBondContact O-N 2.89Å; A584-Q587 VanDerWaalsContact O-N 3.14Å
588F71.8Confident71.7Confident54 Ų5481 Ų8124%0.23743%0.426CS..THydrogen-bonded Turntrans-92.79.6176.6-67.3-71.2000114.2A561 L564 A584 C585 K586 I590 L604 L608A561-F588 HydrophobicContact CB-CE1 4.37Å; A561-F588 HydrophobicContact CB-CZ 3.81Å; L564-F588 HydrophobicContact CD1-CE2 3.86Å; A584-F588 WeakPolarHBondContact O-CD2 3.38Å; A584-F588 PolarHBondContact O-N 3.34Å; A584-F588 VanDerWaalsContact O-N 3.11Å; C585-F588 PolarHBondContact O-N 2.91Å; K586-F588 VanDerWaalsContact C-N 3.29Å; K586-F588 PolarHBondContact O-N 3.29Å; F588-I590 VanDerWaalsContact C-N 3.3Å; F588-I590 HydrophobicContact CB-CD1 4.28Å; F588-I590 HydrophobicContact CB-CG1 4.22Å; F588-I590 PolarHBondContact O-N 3.36Å; F588-L604 HydrophobicContact CD2-CD2 4.06Å; F588-L608 HydrophobicContact CD1-CD2 4.09Å; F588-L608 HydrophobicContact CD2-CD1 4.26Å; F588-L608 HydrophobicContact CE1-CD2 3.77Å; F588-L608 HydrophobicContact CE2-CD1 4.01Å; F588-L608 HydrophobicContact CE2-CD2 4.45Å; F588-L608 HydrophobicContact CZ-CD1 4.26Å; F588-L608 HydrophobicContact CZ-CD2 3.97Å
589G69.6Low71.8Confident65 Ų6582.1 Ų82.167%0.6743%0.431SS*.THydrogen-bonded Turntrans70.819.5175.600000115C585 K586C585-G589 PolarHBondContact O-N 3.32Å; K586-G589 PolarHBondContact O-N 3.27Å
590I76.5Confident71.8Confident33 Ų3377.3 Ų77.317%0.16940%0.401CS..  trans-83.3117.3-179.3-51.3174.8000108.9C585 F588 T592 A603 L604 R607C585-I590 HydrophobicContact CB-CB 4.2Å; C585-I590 PolarHBondContact O-N 3.2Å; F588-I590 VanDerWaalsContact C-N 3.3Å; F588-I590 HydrophobicContact CB-CD1 4.28Å; F588-I590 HydrophobicContact CB-CG1 4.22Å; F588-I590 PolarHBondContact O-N 3.36Å; I590-T592 HydrophobicContact CB-CG2 4.48Å; I590-T592 HydrophobicContact CG2-CG2 3.75Å; I590-T592 PolarHBondContact O-N 2.87Å; I590-A603 HydrophobicContact CG2-CB 4.08Å; I590-L604 HydrophobicContact CD1-CD2 4.04Å; I590-L604 HydrophobicContact CD1-CG 4.49Å; I590-R607 HydrophobicContact CD1-CB 3.76Å; I590-R607 HydrophobicContact CD1-CG 4.03Å; I590-R607 HydrophobicContact CG1-CB 4.38Å; I590-R607 HydrophobicContact CG1-CG 4.2Å
591K64.1Low71.8Confident207 Ų20776 Ų7690%0.939%0.392SS*.  trans-77.6100.1173.5-70.9-177.2-179.3177.60109.3
592T60.3Low72Confident54 Ų5479.5 Ų79.533%0.33141%0.411SS..  trans-99.4116.5178.450.60000111.2C585 I590 L600 A603C585-T592 HydrophobicContact CB-CG2 3.99Å; I590-T592 HydrophobicContact CB-CG2 4.48Å; I590-T592 HydrophobicContact CG2-CG2 3.75Å; I590-T592 PolarHBondContact O-N 2.87Å; T592-L600 HydrophobicContact CG2-CD2 3.65Å; T592-A603 HydrophobicContact CG2-CB 4.49Å
593T55.4Low71.9Confident152 Ų15276 Ų7693%0.93340%0.4SS*.  trans-90.9-10.7170.736.20000112.7
594G58.1Low71.8Confident20 Ų2071.4 Ų71.421%0.20638%0.378CS..  trans-81.3133.9-178.800000114
595T60Low72Confident115 Ų11574.2 Ų74.271%0.70639%0.393SS*.  trans-89.8-10.8172460000113.2
596K74.9Confident72.1Confident143 Ų14381.7 Ų81.762%0.62243%0.428SS*.SBendtrans-83141.2-178.5-65179.5179.6176.80111.1Q598K596-Q598 VanDerWaalsContact C-N 3.31Å; K596-Q598 PolarHBondContact O-N 3.32Å
597K77.8Confident71.9Confident72 Ų7281.4 Ų81.431%0.31342%0.422SS..Hα-helixtrans-63.8-35.3-178.2-174.3171.1167.61730112.8G574 L576 V578 L581 L600 I601G574-K597 WeakPolarHBondContact O-CE 3.48Å; G574-K597 PolarHBondContact O-NZ 3.1Å; L576-K597 WeakPolarHBondContact O-CE 3.48Å; L576-K597 PolarHBondContact O-NZ 3.13Å; V578-K597 HydrophobicContact CG2-CB 3.85Å; V578-K597 HydrophobicContact CG2-CD 3.97Å; V578-K597 HydrophobicContact CG2-CG 3.96Å; L581-K597 HydrophobicContact CD1-CD 4.44Å; L581-K597 HydrophobicContact CD1-CG 3.78Å; K597-L600 PolarHBondContact O-N 3.3Å; K597-I601 HydrophobicContact CG-CD1 4.15Å; K597-I601 WeakPolarHBondContact O-CG1 2.97Å; K597-I601 PolarHBondContact O-N 2.64Å
598Q76.7Confident71.5Confident110 Ų11077.7 Ų77.751%0.51441%0.406SS..Hα-helixtrans-67.1-45-178.8-167.258.83700111.5K596 L600 I601 D602K596-Q598 VanDerWaalsContact C-N 3.31Å; K596-Q598 PolarHBondContact O-N 3.32Å; Q598-L600 PolarHBondContact O-N 3.11Å; Q598-I601 WeakPolarHBondContact O-CA 3.37Å; Q598-I601 WeakPolarHBondContact O-CB 3.31Å; Q598-I601 PolarHBondContact O-N 2.81Å; Q598-D602 PolarHBondContact NE2-OD1 3.19Å; Q598-D602 VanDerWaalsContact O-CG 3.32Å; Q598-D602 PolarHBondContact O-N 2.87Å
599D78.8Confident70.8Confident75 Ų7578 Ų7840%0.40143%0.425SS..Hα-helixtrans-58.2-34.3178.1-49.2-4000112.8A603D599-A603 VanDerWaalsContact O-CB 3.31Å; D599-A603 WeakPolarHBondContact O-CB 3.28Å; D599-A603 PolarHBondContact O-N 3.47Å; D599-A603 VanDerWaalsContact O-N 3.09Å
600L77.3Confident69.8Low0 Ų082.4 Ų82.40%045%0.445CS..Hα-helixtrans-72.1-35.8175.9-61.6174.6000112.4V578 L581 K582 T592 K597 Q598 L604V578-L600 HydrophobicContact CG1-CD1 3.91Å; L581-L600 HydrophobicContact CB-CB 4.12Å; L581-L600 HydrophobicContact CB-CD1 4.03Å; K582-L600 HydrophobicContact CG-CD1 3.62Å; K582-L600 HydrophobicContact CG-CD2 4.27Å; T592-L600 HydrophobicContact CG2-CD2 3.65Å; K597-L600 PolarHBondContact O-N 3.3Å; Q598-L600 PolarHBondContact O-N 3.11Å; L600-L604 WeakPolarHBondContact O-CB 3.43Å; L600-L604 WeakPolarHBondContact O-CD1 3.41Å; L600-L604 WeakPolarHBondContact O-CG 3.34Å; L600-L604 PolarHBondContact O-N 3.14Å; L600-L604 VanDerWaalsContact O-N 3.16Å
601I77.3Confident69.4Low12 Ų1284.9 Ų84.96%0.06246%0.459CS..Hα-helixtrans-69.8-44.7177.1-67.3167.1000109.6L573 L581 K597 Q598 L604 N605L573-I601 HydrophobicContact CB-CG1 4.49Å; L573-I601 HydrophobicContact CB-CG2 4.2Å; L581-I601 HydrophobicContact CD1-CD1 4.27Å; L581-I601 HydrophobicContact CD1-CG1 3.89Å; L581-I601 HydrophobicContact CD2-CG1 4.23Å; K597-I601 HydrophobicContact CG-CD1 4.15Å; K597-I601 WeakPolarHBondContact O-CG1 2.97Å; K597-I601 PolarHBondContact O-N 2.64Å; Q598-I601 WeakPolarHBondContact O-CA 3.37Å; Q598-I601 WeakPolarHBondContact O-CB 3.31Å; Q598-I601 PolarHBondContact O-N 2.81Å; I601-L604 PolarHBondContact O-N 2.98Å; I601-N605 WeakPolarHBondContact O-CB 3.45Å; I601-N605 VanDerWaalsContact O-CG 3.31Å; I601-N605 PolarHBondContact O-N 2.9Å; I601-N605 PolarHBondContact O-ND2 3.12Å
602D79.4Confident69.7Low74 Ų7478.5 Ų78.540%0.39644%0.436SS..Hα-helixtrans-64.5-42.7-179.7-62.3-18.3000110.8Q598 L604 N605 E606Q598-D602 PolarHBondContact NE2-OD1 3.19Å; Q598-D602 VanDerWaalsContact O-CG 3.32Å; Q598-D602 PolarHBondContact O-N 2.87Å; D602-L604 PolarHBondContact O-N 3.12Å; D602-N605 PolarHBondContact O-N 3.16Å; D602-E606 WeakPolarHBondContact O-CB 3.37Å; D602-E606 PolarHBondContact O-N 2.74Å
603A74.4Confident70.2Confident21 Ų2179.8 Ų79.817%0.17444%0.441CS..Hα-helixtrans-65.6-34.8176.300000113.5I590 T592 D599 R607I590-A603 HydrophobicContact CG2-CB 4.08Å; T592-A603 HydrophobicContact CG2-CB 4.49Å; D599-A603 VanDerWaalsContact O-CB 3.31Å; D599-A603 WeakPolarHBondContact O-CB 3.28Å; D599-A603 PolarHBondContact O-N 3.47Å; D599-A603 VanDerWaalsContact O-N 3.09Å; A603-R607 WeakPolarHBondContact O-CB 3.18Å; A603-R607 PolarHBondContact O-N 3.31Å
604L75.1Confident71.1Confident2 Ų275.6 Ų75.61%0.0141%0.413CS..Hα-helixtrans-70.5-40.5173.8-79.8165.8000111.6L573 L581 A584 F588 I590 L600 I601 D602 R607 L608L573-L604 HydrophobicContact CD2-CD1 4.48Å; L581-L604 HydrophobicContact CD2-CD1 3.85Å; A584-L604 HydrophobicContact CB-CD1 4.04Å; A584-L604 HydrophobicContact CB-CD2 4.2Å; F588-L604 HydrophobicContact CD2-CD2 4.06Å; I590-L604 HydrophobicContact CD1-CD2 4.04Å; I590-L604 HydrophobicContact CD1-CG 4.49Å; L600-L604 WeakPolarHBondContact O-CB 3.43Å; L600-L604 WeakPolarHBondContact O-CD1 3.41Å; L600-L604 WeakPolarHBondContact O-CG 3.34Å; L600-L604 PolarHBondContact O-N 3.14Å; L600-L604 VanDerWaalsContact O-N 3.16Å; I601-L604 PolarHBondContact O-N 2.98Å; D602-L604 PolarHBondContact O-N 3.12Å; L604-R607 PolarHBondContact O-N 3.13Å; L604-L608 HydrophobicContact CD2-CD1 4.17Å; L604-L608 WeakPolarHBondContact O-CB 3.38Å; L604-L608 PolarHBondContact O-N 2.93Å
605N76.9Confident71.9Confident61 Ų6179.1 Ų79.133%0.32643%0.425SS..Hα-helixtrans-64.2-40.3175.7-75.4-26.1000111.9M568 L573 I601 D602 R607 G609M568-N605 WeakPolarHBondContact CG-OD1 3.06Å; L573-N605 WeakPolarHBondContact CD1-OD1 3.37Å; I601-N605 WeakPolarHBondContact O-CB 3.45Å; I601-N605 VanDerWaalsContact O-CG 3.31Å; I601-N605 PolarHBondContact O-N 2.9Å; I601-N605 PolarHBondContact O-ND2 3.12Å; D602-N605 PolarHBondContact O-N 3.16Å; N605-R607 PolarHBondContact O-N 2.9Å; N605-G609 VanDerWaalsContact O-CA 3.23Å; N605-G609 WeakPolarHBondContact O-CA 3.5Å; N605-G609 PolarHBondContact O-N 2.71Å
606E75.6Confident72.7Confident157 Ų15776.7 Ų76.773%0.73441%0.407SS*.Hα-helixtrans-66.5-37.4179.3-166.8176.4-168.500111.9D602 S610D602-E606 WeakPolarHBondContact O-CB 3.37Å; D602-E606 PolarHBondContact O-N 2.74Å; E606-S610 PolarHBondContact O-OG 3.42Å
607R73.4Confident72.5Confident171 Ų17171.9 Ų71.965%0.64539%0.391SS*.Hα-helixtrans-83.5-30.5-177.5-169.258.5170.3178.83114.4I590 A603 L604 N605I590-R607 HydrophobicContact CD1-CB 3.76Å; I590-R607 HydrophobicContact CD1-CG 4.03Å; I590-R607 HydrophobicContact CG1-CB 4.38Å; I590-R607 HydrophobicContact CG1-CG 4.2Å; A603-R607 WeakPolarHBondContact O-CB 3.18Å; A603-R607 PolarHBondContact O-N 3.31Å; L604-R607 PolarHBondContact O-N 3.13Å; N605-R607 PolarHBondContact O-N 2.9Å
608L67.1Low72.1Confident34 Ų3471.9 Ų71.918%0.17840%0.397CS..Hα-helixtrans-103.2-13.7-178.2-68.6165.7000113M568 F588 L604M568-L608 HydrophobicContact CE-CB 3.89Å; M568-L608 WeakPolarHBondContact CE-O 3.45Å; M568-L608 HydrophobicContact SD-CB 3.61Å; F588-L608 HydrophobicContact CD1-CD2 4.09Å; F588-L608 HydrophobicContact CD2-CD1 4.26Å; F588-L608 HydrophobicContact CE1-CD2 3.77Å; F588-L608 HydrophobicContact CE2-CD1 4.01Å; F588-L608 HydrophobicContact CE2-CD2 4.45Å; F588-L608 HydrophobicContact CZ-CD1 4.26Å; F588-L608 HydrophobicContact CZ-CD2 3.97Å; L604-L608 HydrophobicContact CD2-CD1 4.17Å; L604-L608 WeakPolarHBondContact O-CB 3.38Å; L604-L608 PolarHBondContact O-N 2.93Å
609G58.7Low71.7Confident61 Ų6168.8 Ų68.863%0.62939%0.388SS*.  trans-89.75.3175.700000114.8N605N605-G609 VanDerWaalsContact O-CA 3.23Å; N605-G609 WeakPolarHBondContact O-CA 3.5Å; N605-G609 PolarHBondContact O-N 2.71Å
610S47Very low71.1Confident157 Ų15768.2 Ų68.2100%1.09839%0.386SS*.  trans-88.10169.5-9.60000112.2E606E606-S610 PolarHBondContact O-OG 3.42Å

Retrieved 610 of 610 residues in 303.1 ms (Link to these results)