A0A087YGZ0_POEFO Loading...

Signal peptide peptidase like 2A

AlphaFold DB , UniProt , Accession A0A087YGZ0, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 536 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.7	Very low	42.6	Very low	229 Å²	229	104.5 Å²	104.5	100%	1.128	61%	0.613	S	S	*	*				0	-9.9	0	-132.8	156	141.7	0	0	112.3
2	E	39.4	Very low	43	Very low	177 Å²	177	105.7 Å²	105.7	83%	0.827	61%	0.614	S	S	*	*			trans	-82.2	-26.5	-176.7	-68.3	167.5	140.2	0	0	115	K4 G5 A6	E2-K4 VanDerWaalsContact C-N 3.29Å; E2-K4 PolarHBondContact O-N 3.47Å; E2-G5 PolarHBondContact O-N 2.65Å; E2-A6 PolarHBondContact O-N 3.45Å
3	A	35.8	Very low	43	Very low	85 Å²	85	101.8 Å²	101.8	70%	0.702	60%	0.597	S	S	*	*	H	α-helix	trans	-67.8	-22.8	-179.4	0	0	0	0	0	114.6	L7	A3-L7 PolarHBondContact O-N 3.16Å
4	K	43.9	Very low	43.2	Very low	186 Å²	186	101 Å²	101	81%	0.809	59%	0.593	S	S	*	*	H	α-helix	trans	-76.1	-31	176.6	-74.5	-174.7	173.7	-174.9	0	112.6	E2 G8	E2-K4 VanDerWaalsContact C-N 3.29Å; E2-K4 PolarHBondContact O-N 3.47Å; K4-G8 PolarHBondContact O-N 2.71Å
5	G	37.5	Very low	43.5	Very low	42 Å²	42	98 Å²	98	43%	0.433	57%	0.573	S	S	.	*	H	α-helix	trans	-74.7	-42.5	176.6	0	0	0	0	0	111.8	E2 L7 G8 V9	E2-G5 PolarHBondContact O-N 2.65Å; G5-L7 PolarHBondContact O-N 2.89Å; G5-G8 PolarHBondContact O-N 3.14Å; G5-V9 WeakPolarHBondContact O-CB 3.33Å; G5-V9 WeakPolarHBondContact O-CG2 3.36Å; G5-V9 PolarHBondContact O-N 3.17Å
6	A	40.7	Very low	43.3	Very low	65 Å²	65	98.3 Å²	98.3	54%	0.537	58%	0.581	S	S	.	*	H	α-helix	trans	-65.6	-39.9	-179.4	0	0	0	0	0	113.1	E2 A10	E2-A6 PolarHBondContact O-N 3.45Å; A6-A10 WeakPolarHBondContact O-CB 2.93Å; A6-A10 PolarHBondContact O-N 3.31Å
7	L	44.6	Very low	43	Very low	106 Å²	106	101.1 Å²	101.1	56%	0.555	59%	0.592	S	S	*	*	H	α-helix	trans	-69.1	-40.3	177.4	-161.8	79	0	0	0	111.8	A3 G5 L11	A3-L7 PolarHBondContact O-N 3.16Å; G5-L7 PolarHBondContact O-N 2.89Å; L7-L11 WeakPolarHBondContact O-CB 3Å; L7-L11 PolarHBondContact O-N 3.12Å
8	G	44	Very low	43	Very low	34 Å²	34	98.1 Å²	98.1	35%	0.351	57%	0.573	S	S	.	*	H	α-helix	trans	-65.8	-41.3	176.7	0	0	0	0	0	112.8	K4 G5 L12	K4-G8 PolarHBondContact O-N 2.71Å; G5-G8 PolarHBondContact O-N 3.14Å; G8-L12 WeakPolarHBondContact O-CB 3.1Å; G8-L12 WeakPolarHBondContact O-CD1 3.04Å; G8-L12 WeakPolarHBondContact O-CG 3.47Å; G8-L12 PolarHBondContact O-N 3.23Å
9	V	47.4	Very low	43.1	Very low	98 Å²	98	97.1 Å²	97.1	59%	0.594	57%	0.572	S	S	*	*	H	α-helix	trans	-72.6	-36.6	177.6	175.1	0	0	0	0	111.6	G5 L12 S13	G5-V9 WeakPolarHBondContact O-CB 3.33Å; G5-V9 WeakPolarHBondContact O-CG2 3.36Å; G5-V9 PolarHBondContact O-N 3.17Å; V9-L12 PolarHBondContact O-N 2.9Å; V9-S13 VanDerWaalsContact O-CB 3.25Å; V9-S13 WeakPolarHBondContact O-CB 3.26Å; V9-S13 PolarHBondContact O-N 3.4Å; V9-S13 PolarHBondContact O-OG 3.07Å
10	A	45.5	Very low	43.1	Very low	47 Å²	47	99.2 Å²	99.2	39%	0.388	58%	0.576	S	S	.	*	H	α-helix	trans	-69.3	-36.4	174.2	0	0	0	0	0	112.4	A6 S13 V14	A6-A10 WeakPolarHBondContact O-CB 2.93Å; A6-A10 PolarHBondContact O-N 3.31Å; A10-S13 WeakPolarHBondContact CA-OG 3.5Å; A10-S13 PolarHBondContact O-OG 2.85Å; A10-S13 VanDerWaalsContact O-OG 3.13Å; A10-V14 WeakPolarHBondContact O-CB 3.5Å; A10-V14 VanDerWaalsContact O-CG2 3.24Å; A10-V14 WeakPolarHBondContact O-CG2 3.29Å; A10-V14 PolarHBondContact O-N 2.85Å
11	L	50.3	Low	43.4	Very low	80 Å²	80	97.7 Å²	97.7	42%	0.419	57%	0.568	S	S	.	*	H	α-helix	trans	-65.5	-48.6	172.7	-137.1	87.6	0	0	0	110.1	L7 S13 V14 I15 V466	L7-L11 WeakPolarHBondContact O-CB 3Å; L7-L11 PolarHBondContact O-N 3.12Å; L11-S13 VanDerWaalsContact C-N 3.33Å; L11-S13 PolarHBondContact O-N 2.04Å; L11-V14 PolarHBondContact O-N 3.45Å; L11-I15 HydrophobicContact CB-CD1 4.4Å; L11-I15 HydrophobicContact CD2-CD1 4.1Å; L11-I15 HydrophobicContact CG-CD1 4.08Å; L11-I15 WeakPolarHBondContact O-CB 3.05Å; L11-I15 WeakPolarHBondContact O-CD1 3.38Å; L11-I15 WeakPolarHBondContact O-CG1 3.49Å; L11-I15 PolarHBondContact O-N 3.02Å; L11-V466 HydrophobicContact CD2-CG1 3.56Å
12	L	47.5	Very low	43.9	Very low	119 Å²	119	91.6 Å²	91.6	62%	0.623	54%	0.54	S	S	*	.	H	α-helix	trans	-62	-36.5	177.5	-85.6	156.5	0	0	0	112.9	G8 V9 S16	G8-L12 WeakPolarHBondContact O-CB 3.1Å; G8-L12 WeakPolarHBondContact O-CD1 3.04Å; G8-L12 WeakPolarHBondContact O-CG 3.47Å; G8-L12 PolarHBondContact O-N 3.23Å; V9-L12 PolarHBondContact O-N 2.9Å; L12-S16 WeakPolarHBondContact O-CB 3.48Å; L12-S16 PolarHBondContact O-N 3.28Å
13	S	42.7	Very low	44.8	Very low	56 Å²	56	84.9 Å²	84.9	39%	0.392	51%	0.512	S	S	.	.	H	α-helix	trans	-75	-38.3	179.6	68.8	0	0	0	0	112.7	V9 A10 L11 I15 S16 L17	V9-S13 VanDerWaalsContact O-CB 3.25Å; V9-S13 WeakPolarHBondContact O-CB 3.26Å; V9-S13 PolarHBondContact O-N 3.4Å; V9-S13 PolarHBondContact O-OG 3.07Å; A10-S13 WeakPolarHBondContact CA-OG 3.5Å; A10-S13 PolarHBondContact O-OG 2.85Å; A10-S13 VanDerWaalsContact O-OG 3.13Å; L11-S13 VanDerWaalsContact C-N 3.33Å; L11-S13 PolarHBondContact O-N 2.04Å; S13-I15 VanDerWaalsContact C-N 3.34Å; S13-S16 PolarHBondContact O-N 3.12Å; S13-L17 WeakPolarHBondContact O-CD1 3.49Å; S13-L17 PolarHBondContact O-N 3.37Å
14	V	45.7	Very low	46.5	Very low	90 Å²	90	81.4 Å²	81.4	55%	0.545	48%	0.482	S	S	.	.	H	α-helix	trans	-68.3	-35.8	172.6	174	0	0	0	0	110.9	A10 L11 I18	A10-V14 WeakPolarHBondContact O-CB 3.5Å; A10-V14 VanDerWaalsContact O-CG2 3.24Å; A10-V14 WeakPolarHBondContact O-CG2 3.29Å; A10-V14 PolarHBondContact O-N 2.85Å; L11-V14 PolarHBondContact O-N 3.45Å; V14-I18 VanDerWaalsContact O-CD1 3.28Å; V14-I18 WeakPolarHBondContact O-CD1 3.28Å; V14-I18 WeakPolarHBondContact O-CG1 3.41Å
15	I	48.2	Very low	48.2	Very low	56 Å²	56	73.2 Å²	73.2	29%	0.287	45%	0.446	S	S	.	.	H	α-helix	trans	-67.1	-36.2	175.9	-72.9	166.4	0	0	0	111.6	L11 S13 L17 I166	L11-I15 HydrophobicContact CB-CD1 4.4Å; L11-I15 HydrophobicContact CD2-CD1 4.1Å; L11-I15 HydrophobicContact CG-CD1 4.08Å; L11-I15 WeakPolarHBondContact O-CB 3.05Å; L11-I15 WeakPolarHBondContact O-CD1 3.38Å; L11-I15 WeakPolarHBondContact O-CG1 3.49Å; L11-I15 PolarHBondContact O-N 3.02Å; S13-I15 VanDerWaalsContact C-N 3.34Å; I15-L17 PolarHBondContact O-N 2.97Å; I15-I166 HydrophobicContact CG2-CD1 3.21Å; I15-I166 HydrophobicContact CG2-CG1 4.24Å; I15-I166 WeakPolarHBondContact O-CD1 3.34Å
16	S	40.4	Very low	50.3	Low	102 Å²	102	71.3 Å²	71.3	71%	0.713	43%	0.426	S	S	*	.	H	α-helix	trans	-80.4	-11.5	-177.5	-155.3	0	0	0	0	114.7	L12 S13	L12-S16 WeakPolarHBondContact O-CB 3.48Å; L12-S16 PolarHBondContact O-N 3.28Å; S13-S16 PolarHBondContact O-N 3.12Å
17	L	37.3	Very low	52.5	Low	146 Å²	146	68.2 Å²	68.2	76%	0.764	40%	0.4	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.9	-2.6	-177.7	-104.5	93.4	0	0	0	114.6	S13 I15 S19	S13-L17 WeakPolarHBondContact O-CD1 3.49Å; S13-L17 PolarHBondContact O-N 3.37Å; I15-L17 PolarHBondContact O-N 2.97Å; L17-S19 PolarHBondContact O-N 3.27Å
18	I	43.8	Very low	54.6	Low	47 Å²	47	63.2 Å²	63.2	24%	0.241	37%	0.374	C	S	.	.	S	Bend	trans	-98	94.1	-167.5	-55.6	157.9	0	0	0	110.7	V14 K165 L474	V14-I18 VanDerWaalsContact O-CD1 3.28Å; V14-I18 WeakPolarHBondContact O-CD1 3.28Å; V14-I18 WeakPolarHBondContact O-CG1 3.41Å; I18-K165 HydrophobicContact CG2-CD 3.88Å; I18-L474 HydrophobicContact CD1-CD2 3.35Å; I18-L474 HydrophobicContact CD1-CG 3.96Å; I18-L474 HydrophobicContact CG1-CD2 3.8Å; I18-L474 HydrophobicContact CG2-CD2 4.22Å
19	S	43.6	Very low	56.8	Low	80 Å²	80	62.6 Å²	62.6	56%	0.559	36%	0.362	S	S	*	.			trans	28.7	120.4	150.8	-49.8	0	0	0	0	119.4	L17 K165	L17-S19 PolarHBondContact O-N 3.27Å; S19-K165 WeakPolarHBondContact O-CD 3.36Å; S19-K165 WeakPolarHBondContact O-CE 3.47Å; S19-K165 WeakPolarHBondContact O-CG 3.43Å
20	Q	44.4	Very low	58.8	Low	138 Å²	138	58 Å²	58	65%	0.645	33%	0.334	S	S	*	.			trans	-49.6	141.2	156.1	-69	162.4	-24.4	0	0	110.7
21	V	48.2	Very low	60.8	Low	68 Å²	68	56.8 Å²	56.8	41%	0.412	32%	0.323	S	S	.	.	B	Isolated β-bridge	trans	-111.8	124.2	171.3	-177.3	0	0	0	0	107.9	C23 K165	V21-C23 PolarHBondContact O-N 3.27Å; V21-K165 HydrophobicContact CG2-CD 3.98Å; V21-K165 HydrophobicContact CG2-CG 3.68Å
22	N	50.2	Low	62.4	Low	102 Å²	102	57 Å²	57	55%	0.545	32%	0.324	S	S	.	.			trans	-69.2	97.3	170	-74.6	-1.3	0	0	0	108.6
23	C	58.7	Low	63.8	Low	36 Å²	36	55.1 Å²	55.1	24%	0.243	33%	0.334	C	S	.	.			trans	-76.6	141.5	170.3	-70.4	0	0	0	0	109.4	V21 E25 F43 Y163	V21-C23 PolarHBondContact O-N 3.27Å; C23-E25 PolarHBondContact O-N 2.85Å; C23-F43 WeakPolarHBondContact O-CE1 3.49Å; C23-Y163 HydrophobicContact CB-CD2 3.61Å; C23-Y163 HydrophobicContact CB-CE2 3.57Å; C23-Y163 VanDerWaalsContact SG-CD2 3.54Å
24	Q	72.3	Confident	65.4	Low	12 Å²	12	57.5 Å²	57.5	6%	0.056	35%	0.351	C	S	.	.	S	Bend	trans	-92	24.1	-179.7	-76.5	172	-33.3	0	0	112.4	F43 T120 N385 V387	Q24-F43 CarbonylContact C-O 3.5Å; Q24-F43 WeakPolarHBondContact CA-O 3.37Å; Q24-F43 WeakPolarHBondContact CB-O 3.32Å; Q24-F43 PolarHBondContact O-N 3.22Å; Q24-T120 HydrophobicContact CB-CG2 3.81Å; Q24-T120 HydrophobicContact CG-CG2 4.3Å; Q24-T120 VanDerWaalsContact OE1-CG2 3.26Å; Q24-N385 VanDerWaalsContact CD-O 3.24Å; Q24-N385 PolarHBondContact NE2-O 2.93Å; Q24-N385 PolarHBondContact OE1-O 3.04Å; Q24-V387 HydrophobicContact CB-CG2 4.24Å
25	E	78	Confident	67.2	Low	14 Å²	14	58 Å²	58	7%	0.065	35%	0.35	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.2	135.5	179.8	-64.7	-179.6	-157.9	0	0	110	C23 L41 F43 Q414	C23-E25 PolarHBondContact O-N 2.85Å; E25-L41 WeakPolarHBondContact CA-O 3.3Å; E25-F43 WeakPolarHBondContact O-CE1 3.05Å; E25-Q414 WeakPolarHBondContact OE2-CA 3.28Å; E25-Q414 WeakPolarHBondContact OE2-CG 3Å
26	A	83.2	Confident	68.9	Low	1 Å²	1	59.2 Å²	59.2	1%	0.008	36%	0.36	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.6	171.4	-179.6	0	0	0	0	0	110.3	L41 F43 L50 Y159 A160	A26-L41 HydrophobicContact CB-CB 3.94Å; A26-L41 HydrophobicContact CB-CD1 4.45Å; A26-L41 PolarHBondContact N-O 2.78Å; A26-L41 WeakPolarHBondContact O-CA 3.25Å; A26-L41 WeakPolarHBondContact O-CB 3.31Å; A26-L41 PolarHBondContact O-N 2.88Å; A26-F43 HydrophobicContact CB-CD1 3.51Å; A26-F43 HydrophobicContact CB-CE1 3.96Å; A26-F43 HydrophobicContact CB-CG 4.19Å; A26-L50 HydrophobicContact CB-CD1 3.49Å; A26-L50 VanDerWaalsContact CB-CD1 3.49Å; A26-Y159 WeakPolarHBondContact CB-O 3.35Å; A26-A160 HydrophobicContact CB-CB 4.07Å
27	V	86.4	Confident	71.1	Confident	0 Å²	0	60.3 Å²	60.3	0%	0	35%	0.348	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.2	135.3	176.4	172.2	0	0	0	0	111.4	D38 Y39 Y159 T413	V27-D38 HydrophobicContact CG1-CB 3.79Å; V27-Y39 WeakPolarHBondContact CA-O 3.35Å; V27-Y159 HydrophobicContact CB-CD1 4.34Å; V27-Y159 HydrophobicContact CB-CE1 3.74Å; V27-Y159 HydrophobicContact CB-CE2 4.41Å; V27-Y159 HydrophobicContact CG1-CE1 3.65Å; V27-Y159 PolarHBondContact N-O 2.9Å; V27-Y159 PolarHBondContact O-N 2.96Å; V27-T413 HydrophobicContact CB-CG2 4.13Å; V27-T413 HydrophobicContact CG2-CG2 3.15Å
28	L	88.9	Confident	73.4	Confident	1 Å²	1	54.4 Å²	54.4	1%	0.005	32%	0.318	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.9	106	166.8	-174.8	64.6	0	0	0	108.4	I30 D38 Y39 L41 L111 M138 V156 L158	L28-I30 HydrophobicContact CD2-CD1 3.81Å; L28-I30 HydrophobicContact CD2-CG1 4.12Å; L28-I30 HydrophobicContact CG-CD1 4.15Å; L28-I30 HydrophobicContact CG-CG1 3.87Å; L28-D38 CarbonylContact O-C 3.57Å; L28-D38 WeakPolarHBondContact O-CA 3.09Å; L28-Y39 PolarHBondContact N-O 2.97Å; L28-Y39 PolarHBondContact O-N 3.06Å; L28-L41 HydrophobicContact CB-CD1 3.75Å; L28-L41 HydrophobicContact CB-CD2 3.91Å; L28-L41 HydrophobicContact CB-CG 3.71Å; L28-L41 HydrophobicContact CD1-CD1 4.39Å; L28-L41 HydrophobicContact CD2-CD2 4.42Å; L28-L111 HydrophobicContact CD1-CD1 3.8Å; L28-L111 HydrophobicContact CD2-CD1 4.03Å; L28-M138 HydrophobicContact CD2-CE 4.44Å; L28-M138 HydrophobicContact CD2-SD 4.11Å; L28-V156 HydrophobicContact CD1-CB 3.79Å; L28-V156 HydrophobicContact CD1-CG1 4.09Å; L28-V156 HydrophobicContact CD1-CG2 4.4Å; L28-L158 HydrophobicContact CD1-CG 4.12Å
29	H	89.4	Confident	75.3	Confident	22 Å²	22	53.1 Å²	53.1	10%	0.102	31%	0.31	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.2	118.9	172.9	-177.9	88.6	0	0	0	109.2	V36 D38 L54 V156 K157 Y159	H29-V36 WeakPolarHBondContact CE1-CG1 3.31Å; H29-D38 IonicContact CE1-OD1 3.44Å; H29-D38 IonicContact CG-OD1 3.38Å; H29-D38 IonicContact ND1-OD1 3.13Å; H29-D38 PolarHBondContact ND1-OD1 2.84Å; H29-D38 IonicContact ND1-OD2 3.76Å; H29-D38 PolarHBondContact ND1-OD2 2.94Å; H29-L54 HydrophobicContact CB-CD1 3.8Å; H29-V156 CarbonylContact O-C 3.56Å; H29-V156 VanDerWaalsContact O-CA 3.28Å; H29-V156 WeakPolarHBondContact O-CA 3.32Å; H29-K157 HydrophobicContact CB-CB 4.28Å; H29-K157 PolarHBondContact N-O 3.33Å; H29-K157 PolarHBondContact O-N 3.36Å; H29-Y159 HydrophobicContact CB-CE1 4.18Å
30	I	89.8	Confident	77.3	Confident	1 Å²	1	49.4 Å²	49.4	1%	0.005	28%	0.284	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.5	127.8	179.3	-48.3	-169.6	0	0	0	109.1	L28 V36 R37 Y39 A146 F150 M154 E155 V156	L28-I30 HydrophobicContact CD2-CD1 3.81Å; L28-I30 HydrophobicContact CD2-CG1 4.12Å; L28-I30 HydrophobicContact CG-CD1 4.15Å; L28-I30 HydrophobicContact CG-CG1 3.87Å; I30-V36 WeakPolarHBondContact O-CA 3.32Å; I30-R37 PolarHBondContact N-O 3.01Å; I30-R37 PolarHBondContact O-N 2.88Å; I30-Y39 HydrophobicContact CB-CE2 4.38Å; I30-Y39 HydrophobicContact CD1-CD2 3.62Å; I30-Y39 HydrophobicContact CD1-CE2 3.59Å; I30-Y39 HydrophobicContact CG1-CD2 3.87Å; I30-Y39 HydrophobicContact CG1-CE2 3.98Å; I30-A146 HydrophobicContact CD1-CB 3.68Å; I30-F150 HydrophobicContact CB-CD2 4.4Å; I30-F150 HydrophobicContact CB-CE2 4.12Å; I30-F150 HydrophobicContact CB-CZ 4.45Å; I30-F150 HydrophobicContact CG2-CD1 4.41Å; I30-F150 HydrophobicContact CG2-CD2 3.74Å; I30-F150 HydrophobicContact CG2-CE2 3.92Å; I30-F150 HydrophobicContact CG2-CG 4Å; I30-F150 HydrophobicContact CG2-CZ 4.32Å; I30-M154 HydrophobicContact CG2-CB 4.1Å; I30-M154 HydrophobicContact CG2-CG 3.9Å; I30-M154 HydrophobicContact CG2-SD 4.31Å; I30-E155 WeakPolarHBondContact CA-O 3.44Å; I30-V156 HydrophobicContact CD1-CG1 4.36Å; I30-V156 HydrophobicContact CG1-CG1 3.98Å; I30-V156 HydrophobicContact CG2-CG1 4.37Å
31	S	88.2	Confident	79.3	Confident	22 Å²	22	42.9 Å²	42.9	15%	0.154	25%	0.253	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.8	151.4	178.3	74.4	0	0	0	0	111.8	L35 E155	S31-L35 WeakPolarHBondContact CA-O 3.44Å; S31-E155 PolarHBondContact N-O 3.28Å; S31-E155 PolarHBondContact O-N 3.4Å; S31-E155 VanDerWaalsContact O-N 3.15Å
32	N	84	Confident	81.1	Confident	83 Å²	83	39.6 Å²	39.6	44%	0.444	23%	0.233	S	C	.	.			trans	-133.1	39.1	170.7	-167.8	6.9	0	0	0	110	S34 L35 F150	N32-S34 PolarHBondContact O-N 3.41Å; N32-L35 PolarHBondContact N-O 3.4Å; N32-F150 HydrophobicContact CB-CD1 3.81Å; N32-F150 HydrophobicContact CB-CE1 4.44Å
33	G	76.1	Confident	82.8	Confident	80 Å²	80	35.3 Å²	35.3	83%	0.825	21%	0.21	S	C	*	.	S	Bend	trans	77.4	-37.6	-179.6	0	0	0	0	0	116.7
34	S	75.8	Confident	84	Confident	106 Å²	106	34 Å²	34	74%	0.741	20%	0.2	S	C	*	.	S	Bend	trans	-112.3	-32.1	-178	58.4	0	0	0	0	114.3	N32	N32-S34 PolarHBondContact O-N 3.41Å
35	L	83.3	Confident	84.4	Confident	100 Å²	100	36.7 Å²	36.7	52%	0.524	21%	0.213	S	C	.	.			trans	-114.3	142.2	179.5	-74.1	160.8	0	0	0	109	S31 N32 F150	S31-L35 WeakPolarHBondContact CA-O 3.44Å; N32-L35 PolarHBondContact N-O 3.4Å; L35-F150 HydrophobicContact CB-CE1 3.82Å; L35-F150 WeakPolarHBondContact O-CE1 2.95Å
36	V	85.5	Confident	84.5	Confident	83 Å²	83	38.8 Å²	38.8	50%	0.503	23%	0.229	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-133.4	133.3	-179.2	174.5	0	0	0	0	108.4	H29 I30	H29-V36 WeakPolarHBondContact CE1-CG1 3.31Å; I30-V36 WeakPolarHBondContact O-CA 3.32Å
37	R	85	Confident	84.5	Confident	125 Å²	125	39.1 Å²	39.1	47%	0.472	23%	0.23	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-143.9	144.4	170.2	-69.3	-166.3	176	-155.8	1.2	111	I30 Y39 F150	I30-R37 PolarHBondContact N-O 3.01Å; I30-R37 PolarHBondContact O-N 2.88Å; R37-Y39 HydrophobicContact CB-CE2 3.78Å; R37-Y39 WeakPolarHBondContact CD-OH 3.16Å; R37-F150 HydrophobicContact CB-CE2 3.82Å; R37-F150 HydrophobicContact CB-CZ 3.8Å; R37-F150 HydrophobicContact CG-CE2 4.02Å; R37-F150 HydrophobicContact CG-CZ 3.82Å
38	D	86.2	Confident	84.4	Confident	22 Å²	22	40.9 Å²	40.9	12%	0.118	24%	0.241	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-111.9	145.1	-179.2	-70.9	20.8	0	0	0	109.1	V27 L28 H29 W412 L416	V27-D38 HydrophobicContact CG1-CB 3.79Å; L28-D38 CarbonylContact O-C 3.57Å; L28-D38 WeakPolarHBondContact O-CA 3.09Å; H29-D38 IonicContact CE1-OD1 3.44Å; H29-D38 IonicContact CG-OD1 3.38Å; H29-D38 IonicContact ND1-OD1 3.13Å; H29-D38 PolarHBondContact ND1-OD1 2.84Å; H29-D38 IonicContact ND1-OD2 3.76Å; H29-D38 PolarHBondContact ND1-OD2 2.94Å; D38-W412 HydrophobicContact CB-CH2 3.76Å; D38-W412 HydrophobicContact CB-CZ3 4.11Å; D38-W412 WeakPolarHBondContact OD2-CH2 3.36Å; D38-W412 WeakPolarHBondContact OD2-CZ3 3.46Å; D38-L416 VanDerWaalsContact C-CD2 3.43Å; D38-L416 HydrophobicContact CB-CD1 3.9Å; D38-L416 HydrophobicContact CB-CD2 3.96Å; D38-L416 WeakPolarHBondContact O-CD2 3.4Å
39	Y	84.9	Confident	84.1	Confident	20 Å²	20	45.6 Å²	45.6	8%	0.078	27%	0.271	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.2	151.3	-179.9	-59.6	-85.7	0	0	0	110.7	V27 L28 I30 R37 D142 S145 A146	V27-Y39 WeakPolarHBondContact CA-O 3.35Å; L28-Y39 PolarHBondContact N-O 2.97Å; L28-Y39 PolarHBondContact O-N 3.06Å; I30-Y39 HydrophobicContact CB-CE2 4.38Å; I30-Y39 HydrophobicContact CD1-CD2 3.62Å; I30-Y39 HydrophobicContact CD1-CE2 3.59Å; I30-Y39 HydrophobicContact CG1-CD2 3.87Å; I30-Y39 HydrophobicContact CG1-CE2 3.98Å; R37-Y39 HydrophobicContact CB-CE2 3.78Å; R37-Y39 WeakPolarHBondContact CD-OH 3.16Å; Y39-D142 HydrophobicContact CD1-CB 3.76Å; Y39-D142 HydrophobicContact CE1-CB 4.35Å; Y39-S145 WeakPolarHBondContact CE1-OG 3.18Å; Y39-A146 HydrophobicContact CE1-CB 4.44Å; Y39-A146 HydrophobicContact CE2-CB 3.71Å; Y39-A146 VanDerWaalsContact OH-CA 3.3Å; Y39-A146 WeakPolarHBondContact OH-CA 2.99Å; Y39-A146 PolarHBondContact OH-N 2.82Å
40	C	85.4	Confident	84	Confident	2 Å²	2	45.7 Å²	45.7	1%	0.014	27%	0.272	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-70.4	136	177.4	174.4	0	0	0	0	112.6	C417	C40-C417 WeakPolarHBondContact CA-SG 3.35Å; C40-C417 VanDerWaalsContact CB-CA 3.44Å; C40-C417 HydrophobicContact CB-CB 3.72Å; C40-C417 WeakPolarHBondContact CB-SG 3.43Å; C40-C417 WeakPolarHBondContact SG-CA 3.45Å; C40-C417 WeakPolarHBondContact SG-CB 3.41Å; C40-C417 CovalentContact SG-SG 2Å; C40-C417 PolarHBondContact SG-SG 3.23Å
41	L	86.3	Confident	83.8	Confident	0 Å²	0	50 Å²	50	0%	0	29%	0.293	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.9	145.7	167.4	-62.3	-178.3	0	0	0	111.5	E25 A26 L28 L111 A136 L137 M138 L158	E25-L41 WeakPolarHBondContact CA-O 3.3Å; A26-L41 HydrophobicContact CB-CB 3.94Å; A26-L41 HydrophobicContact CB-CD1 4.45Å; A26-L41 PolarHBondContact N-O 2.78Å; A26-L41 WeakPolarHBondContact O-CA 3.25Å; A26-L41 WeakPolarHBondContact O-CB 3.31Å; A26-L41 PolarHBondContact O-N 2.88Å; L28-L41 HydrophobicContact CB-CD1 3.75Å; L28-L41 HydrophobicContact CB-CD2 3.91Å; L28-L41 HydrophobicContact CB-CG 3.71Å; L28-L41 HydrophobicContact CD1-CD1 4.39Å; L28-L41 HydrophobicContact CD2-CD2 4.42Å; L41-L111 HydrophobicContact CD1-CD2 3.93Å; L41-L111 HydrophobicContact CD2-CD2 3.59Å; L41-L111 HydrophobicContact CG-CD2 4.42Å; L41-A136 HydrophobicContact CB-CB 4.12Å; L41-A136 HydrophobicContact CD1-CB 3.99Å; L41-A136 HydrophobicContact CD2-CB 4.46Å; L41-A136 HydrophobicContact CG-CB 4.44Å; L41-L137 CarbonylContact C-O 3.57Å; L41-L137 VanDerWaalsContact CA-O 3.26Å; L41-L137 WeakPolarHBondContact CA-O 3.42Å; L41-M138 HydrophobicContact CD2-CB 3.66Å; L41-M138 HydrophobicContact CD2-SD 4.49Å; L41-L158 HydrophobicContact CD1-CD2 3.78Å; L41-L158 HydrophobicContact CD1-CG 4.2Å
42	V	85.3	Confident	83.5	Confident	0 Å²	0	53.2 Å²	53.2	0%	0	31%	0.305	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.7	123.7	166.4	-179.4	0	0	0	0	108.4	L118 T120 A136 L137 I389	V42-L118 HydrophobicContact CB-CB 4.48Å; V42-L118 HydrophobicContact CG2-CB 3.91Å; V42-L118 HydrophobicContact CG2-CD1 4.1Å; V42-T120 HydrophobicContact CG1-CG2 3.64Å; V42-A136 CarbonylContact O-C 3.55Å; V42-A136 WeakPolarHBondContact O-CA 3.27Å; V42-L137 HydrophobicContact CB-CB 4.47Å; V42-L137 PolarHBondContact N-O 2.79Å; V42-L137 PolarHBondContact O-N 3.33Å; V42-I389 HydrophobicContact CG2-CD1 3.63Å; V42-I389 HydrophobicContact CG2-CG1 4.31Å
43	F	86.5	Confident	83.4	Confident	12 Å²	12	52 Å²	52	5%	0.053	30%	0.301	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.4	168.4	-179.6	85.6	-72	0	0	0	110.1	C23 Q24 E25 A26 H45 L50 A136 A160	C23-F43 WeakPolarHBondContact O-CE1 3.49Å; Q24-F43 CarbonylContact C-O 3.5Å; Q24-F43 WeakPolarHBondContact CA-O 3.37Å; Q24-F43 WeakPolarHBondContact CB-O 3.32Å; Q24-F43 PolarHBondContact O-N 3.22Å; E25-F43 WeakPolarHBondContact O-CE1 3.05Å; A26-F43 HydrophobicContact CB-CD1 3.51Å; A26-F43 HydrophobicContact CB-CE1 3.96Å; A26-F43 HydrophobicContact CB-CG 4.19Å; F43-H45 HydrophobicContact CE2-CB 4.31Å; F43-L50 HydrophobicContact CB-CD1 4.22Å; F43-L50 HydrophobicContact CD1-CD1 4.27Å; F43-L50 HydrophobicContact CD2-CD1 3.95Å; F43-L50 HydrophobicContact CD2-CG 4.38Å; F43-L50 HydrophobicContact CE2-CD1 4.39Å; F43-L50 HydrophobicContact CG-CD1 3.88Å; F43-A136 HydrophobicContact CB-CB 4.02Å; F43-A160 HydrophobicContact CD1-CB 4.47Å; F43-A160 HydrophobicContact CE1-CB 3.59Å; F43-A160 HydrophobicContact CE2-CB 4.33Å; F43-A160 HydrophobicContact CZ-CB 3.5Å
44	N	84.3	Confident	83.8	Confident	8 Å²	8	50.5 Å²	50.5	4%	0.043	27%	0.274	C	S	.	.			trans	-122.2	125.8	174.3	171.8	3.9	0	0	0	109	S46 W47 P121 Y128	N44-S46 PolarHBondContact O-N 2.95Å; N44-S46 WeakPolarHBondContact OD1-CB 3.49Å; N44-S46 PolarHBondContact OD1-N 3.09Å; N44-S46 PolarHBondContact OD1-OG 3.22Å; N44-W47 WeakPolarHBondContact O-CB 3.48Å; N44-W47 PolarHBondContact O-N 3.02Å; N44-P121 HydrophobicContact CB-CG 4.1Å; N44-P121 VanDerWaalsContact CB-O 3.23Å; N44-P121 WeakPolarHBondContact CB-O 3.37Å; N44-P121 PolarHBondContact ND2-O 3.01Å; N44-Y128 PolarHBondContact ND2-OH 3.2Å
45	H	80.1	Confident	84.1	Confident	69 Å²	69	52.6 Å²	52.6	32%	0.319	28%	0.277	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.3	-15	-177	71.6	79.4	0	0	0	113.5	F43 W47	F43-H45 HydrophobicContact CE2-CB 4.31Å; H45-W47 VanDerWaalsContact C-N 3.26Å
46	S	80.6	Confident	84.2	Confident	57 Å²	57	54.4 Å²	54.4	40%	0.399	28%	0.28	S	S	.	.	T	Hydrogen-bonded Turn	trans	-73.3	-17.4	172.5	-62	0	0	0	0	112.9	N44	N44-S46 PolarHBondContact O-N 2.95Å; N44-S46 WeakPolarHBondContact OD1-CB 3.49Å; N44-S46 PolarHBondContact OD1-N 3.09Å; N44-S46 PolarHBondContact OD1-OG 3.22Å
47	W	83.2	Confident	84.2	Confident	9 Å²	9	50.8 Å²	50.8	3%	0.034	26%	0.259	C	S	.	.	S	Bend	trans	-81.8	-171.5	168.8	-60.9	111.2	0	0	0	111.1	N44 H45 P49 P121 A123 Y128 V131 L135	N44-W47 WeakPolarHBondContact O-CB 3.48Å; N44-W47 PolarHBondContact O-N 3.02Å; H45-W47 VanDerWaalsContact C-N 3.26Å; W47-P49 WeakPolarHBondContact O-CD 3.47Å; W47-P49 VanDerWaalsContact O-N 3.15Å; W47-P121 PolarHBondContact NE1-O 2.9Å; W47-A123 HydrophobicContact CH2-CB 3.46Å; W47-A123 VanDerWaalsContact CH2-CB 3.46Å; W47-A123 HydrophobicContact CZ2-CB 3.46Å; W47-A123 VanDerWaalsContact CZ2-CB 3.46Å; W47-Y128 AromaticContact CD2-CD1 3.5Å; W47-Y128 HydrophobicContact CD2-CD1 3.5Å; W47-Y128 AromaticContact CD2-CE1 3.85Å; W47-Y128 HydrophobicContact CD2-CE1 3.85Å; W47-Y128 AromaticContact CE2-CD1 3.54Å; W47-Y128 AromaticContact CE2-CE1 3.4Å; W47-Y128 VanDerWaalsContact CE2-CE1 3.4Å; W47-Y128 AromaticContact CE3-CD1 3.63Å; W47-Y128 HydrophobicContact CE3-CD1 3.63Å; W47-Y128 HydrophobicContact CE3-CE1 4.36Å; W47-Y128 HydrophobicContact CE3-CG 4.46Å; W47-Y128 HydrophobicContact CG-CD1 4.11Å; W47-Y128 HydrophobicContact CG-CE1 4.32Å; W47-Y128 AromaticContact CH2-CD1 3.83Å; W47-Y128 HydrophobicContact CH2-CD1 3.83Å; W47-Y128 HydrophobicContact CH2-CE1 4.1Å; W47-Y128 HydrophobicContact CH2-CG 4.49Å; W47-Y128 AromaticContact CZ2-CD1 3.72Å; W47-Y128 HydrophobicContact CZ2-CD1 3.72Å; W47-Y128 AromaticContact CZ2-CE1 3.55Å; W47-Y128 HydrophobicContact CZ2-CE1 3.55Å; W47-Y128 AromaticContact CZ3-CD1 3.8Å; W47-Y128 HydrophobicContact CZ3-CD1 3.8Å; W47-Y128 HydrophobicContact CZ3-CE1 4.48Å; W47-Y128 HydrophobicContact CZ3-CG 4.38Å; W47-Y128 AromaticContact NE1-CE1 3.65Å; W47-V131 HydrophobicContact CE3-CB 3.66Å; W47-V131 HydrophobicContact CE3-CG1 4.01Å; W47-V131 HydrophobicContact CE3-CG2 4.04Å; W47-V131 HydrophobicContact CH2-CG2 4.31Å; W47-V131 HydrophobicContact CZ3-CB 3.6Å; W47-V131 HydrophobicContact CZ3-CG1 4.28Å; W47-V131 HydrophobicContact CZ3-CG2 3.46Å; W47-V131 VanDerWaalsContact CZ3-CG2 3.46Å; W47-L135 HydrophobicContact CD2-CD2 4.31Å; W47-L135 HydrophobicContact CZ2-CD2 4.39Å
48	T	83.1	Confident	84.2	Confident	37 Å²	37	48.4 Å²	48.4	23%	0.227	26%	0.258	C	S	.	.	S	Bend	trans	-54	120.5	172.2	-45.6	0	0	0	0	110.2	V131 L132 I133 P134	T48-V131 PolarHBondContact OG1-O 2.63Å; T48-L132 WeakPolarHBondContact OG1-CA 3.21Å; T48-L132 PolarHBondContact OG1-O 3.48Å; T48-I133 PolarHBondContact OG1-N 2.83Å; T48-I133 PolarHBondContact OG1-O 2.78Å; T48-P134 HydrophobicContact CG2-CG 4.29Å
49	P	83.8	Confident	84.4	Confident	99 Å²	99	50.6 Å²	50.6	64%	0.643	27%	0.272	S	S	*	.	P	Polyproline II helix	trans	-67.6	147.6	-174.4	27.1	-34.2	0	0	0	111	W47	W47-P49 WeakPolarHBondContact O-CD 3.47Å; W47-P49 VanDerWaalsContact O-N 3.15Å
50	L	85.9	Confident	84.7	Confident	24 Å²	24	51.5 Å²	51.5	13%	0.126	28%	0.276	C	S	.	.	P	Polyproline II helix	trans	-89.7	152.2	172.5	-71.7	171.8	0	0	0	110.3	A26 F43 P134 L158 A160	A26-L50 HydrophobicContact CB-CD1 3.49Å; A26-L50 VanDerWaalsContact CB-CD1 3.49Å; F43-L50 HydrophobicContact CB-CD1 4.22Å; F43-L50 HydrophobicContact CD1-CD1 4.27Å; F43-L50 HydrophobicContact CD2-CD1 3.95Å; F43-L50 HydrophobicContact CD2-CG 4.38Å; F43-L50 HydrophobicContact CE2-CD1 4.39Å; F43-L50 HydrophobicContact CG-CD1 3.88Å; L50-P134 HydrophobicContact CD2-CB 3.66Å; L50-P134 HydrophobicContact CD2-CG 4.23Å; L50-L158 HydrophobicContact CD2-CB 3.55Å; L50-L158 HydrophobicContact CD2-CD2 4.38Å; L50-A160 HydrophobicContact CB-CB 3.8Å; L50-A160 HydrophobicContact CD1-CB 4.26Å
51	E	87.2	Confident	84.9	Confident	92 Å²	92	57.6 Å²	57.6	43%	0.43	30%	0.302	S	S	.	.	B	Isolated β-bridge	trans	-66.6	148.3	175.7	-69.4	-64.8	162.6	0	0	111.5	K56 A57 Y159 A160	E51-K56 HydrophobicContact CB-CB 4.34Å; E51-K56 HydrophobicContact CG-CB 4.36Å; E51-A57 HydrophobicContact CB-CB 4.39Å; E51-Y159 CarbonylContact O-C 3.45Å; E51-Y159 WeakPolarHBondContact O-CA 3.49Å; E51-Y159 VanDerWaalsContact O-CB 3.26Å; E51-Y159 WeakPolarHBondContact O-CB 3.24Å; E51-A160 PolarHBondContact O-N 3.48Å
52	E	81.8	Confident	85.2	Confident	89 Å²	89	58.2 Å²	58.2	42%	0.416	31%	0.306	S	S	.	.	S	Bend	trans	-81.4	-20.6	-173.9	-62.2	178	177	0	0	113.6	A160 P161 Q162	E52-A160 WeakPolarHBondContact CA-O 2.89Å; E52-P161 WeakPolarHBondContact O-CA 3.33Å; E52-Q162 HydrophobicContact CG-CG 4.05Å; E52-Q162 VanDerWaalsContact OE1-CD 3.28Å; E52-Q162 PolarHBondContact OE1-NE2 2.94Å
53	T	81.5	Confident	85.4	Confident	57 Å²	57	59.2 Å²	59.2	35%	0.35	31%	0.311	S	S	.	.	S	Bend	trans	-133.5	146.6	-172.8	55	0	0	0	0	110.8	D55 K56 A57	T53-D55 PolarHBondContact O-N 2.99Å; T53-K56 PolarHBondContact O-N 3.37Å; T53-K56 WeakPolarHBondContact OG1-CG 3.5Å; T53-A57 PolarHBondContact O-N 3.45Å
54	L	83.7	Confident	85.6	Confident	49 Å²	49	61.4 Å²	61.4	26%	0.257	32%	0.324	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.2	-31	179.9	-177.1	64.6	0	0	0	113	H29 A57 K157 Y159	H29-L54 HydrophobicContact CB-CD1 3.8Å; L54-A57 PolarHBondContact O-N 3.38Å; L54-K157 HydrophobicContact CD1-CB 4.11Å; L54-K157 HydrophobicContact CD1-CD 3.75Å; L54-Y159 HydrophobicContact CB-CE1 4.48Å; L54-Y159 HydrophobicContact CD1-CD1 3.93Å; L54-Y159 HydrophobicContact CD1-CE1 3.9Å
55	D	82.6	Confident	85.8	Confident	151 Å²	151	62.3 Å²	62.3	81%	0.807	33%	0.328	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.8	-29.5	-177.6	-59.8	-41	0	0	0	113	T53	T53-D55 PolarHBondContact O-N 2.99Å
56	K	85.4	Confident	86	Confident	138 Å²	138	59.9 Å²	59.9	60%	0.6	32%	0.318	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.5	-18.9	176.2	-64.4	-179.9	-174.1	175.4	0	112.5	E51 T53 T58	E51-K56 HydrophobicContact CB-CB 4.34Å; E51-K56 HydrophobicContact CG-CB 4.36Å; T53-K56 PolarHBondContact O-N 3.37Å; T53-K56 WeakPolarHBondContact OG1-CG 3.5Å; K56-T58 PolarHBondContact O-N 3.27Å
57	A	84.8	Confident	86.1	Confident	6 Å²	6	62.5 Å²	62.5	5%	0.05	34%	0.337	C	S	.	.	S	Bend	trans	-66.1	129.9	-177.1	0	0	0	0	0	112.3	E51 T53 L54 K157	E51-A57 HydrophobicContact CB-CB 4.39Å; T53-A57 PolarHBondContact O-N 3.45Å; L54-A57 PolarHBondContact O-N 3.38Å; A57-K157 HydrophobicContact CB-CB 4.04Å; A57-K157 HydrophobicContact CB-CD 4.48Å; A57-K157 HydrophobicContact CB-CG 4.5Å
58	T	86.3	Confident	86.2	Confident	76 Å²	76	64 Å²	64	47%	0.466	35%	0.347	S	S	.	.	P	Polyproline II helix	trans	-69.6	139	177.8	-39.4	0	0	0	0	110.7	K56 Y60	K56-T58 PolarHBondContact O-N 3.27Å; T58-Y60 WeakPolarHBondContact CB-OH 3.42Å; T58-Y60 HydrophobicContact CG2-CE1 3.96Å; T58-Y60 HydrophobicContact CG2-CE2 4.35Å
59	T	89.8	Confident	86.2	Confident	67 Å²	67	65 Å²	65	41%	0.411	35%	0.353	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.6	129.5	178.3	-48.7	0	0	0	0	109.9	E155 K157	T59-E155 HydrophobicContact CG2-CB 3.97Å; T59-K157 HydrophobicContact CG2-CG 4.45Å; T59-K157 WeakPolarHBondContact OG1-CE 3.28Å
60	Y	90.9	Very high	86.4	Confident	40 Å²	40	60.6 Å²	60.6	16%	0.157	32%	0.324	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.3	146.3	176.7	-57.1	-72.1	0	0	0	110.4	T58 A85 K108 A109 E155 V156 L158	T58-Y60 WeakPolarHBondContact CB-OH 3.42Å; T58-Y60 HydrophobicContact CG2-CE1 3.96Å; T58-Y60 HydrophobicContact CG2-CE2 4.35Å; Y60-A85 HydrophobicContact CG-CB 4.17Å; Y60-K108 HydrophobicContact CD1-CB 3.94Å; Y60-K108 HydrophobicContact CE1-CB 3.46Å; Y60-K108 VanDerWaalsContact CE1-CB 3.46Å; Y60-K108 HydrophobicContact CE1-CG 4.26Å; Y60-A109 HydrophobicContact CD2-CB 4.32Å; Y60-A109 HydrophobicContact CE2-CB 4.28Å; Y60-E155 WeakPolarHBondContact O-CA 3.49Å; Y60-V156 PolarHBondContact N-O 2.89Å; Y60-V156 WeakPolarHBondContact O-CG2 3.19Å; Y60-V156 PolarHBondContact O-N 2.9Å; Y60-L158 HydrophobicContact CD2-CD1 4.09Å; Y60-L158 HydrophobicContact CE2-CD1 4.41Å
61	K	90.9	Very high	86.4	Confident	130 Å²	130	61.1 Å²	61.1	57%	0.565	33%	0.329	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-78.7	132.5	164.3	-70.1	-172.6	176.2	-174.5	0	109	K84 A85	K61-K84 HydrophobicContact CB-CD 4.28Å; K61-K84 HydrophobicContact CB-CG 4.28Å; K61-K84 WeakPolarHBondContact O-CB 3.02Å; K61-A85 PolarHBondContact O-N 2.9Å
62	L	90.6	Very high	86.2	Confident	13 Å²	13	61.7 Å²	61.7	7%	0.068	34%	0.335	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.6	130.4	-179.7	-162.3	66.5	0	0	0	110.8	A85 V87 L111 F143 M154 V156	L62-A85 CarbonylContact C-O 3.56Å; L62-A85 WeakPolarHBondContact CA-O 3.33Å; L62-A85 HydrophobicContact CD1-CB 3.98Å; L62-V87 HydrophobicContact CD1-CG2 3.36Å; L62-V87 HydrophobicContact CD2-CG2 3.77Å; L62-V87 HydrophobicContact CG-CG2 3.64Å; L62-L111 HydrophobicContact CD1-CD1 3.81Å; L62-F143 HydrophobicContact CD2-CE2 3.98Å; L62-M154 HydrophobicContact CB-CB 3.91Å; L62-M154 HydrophobicContact CD2-CB 4.32Å; L62-M154 HydrophobicContact CD2-CE 4.43Å; L62-M154 HydrophobicContact CD2-SD 4.01Å; L62-M154 PolarHBondContact N-O 3.24Å; L62-V156 HydrophobicContact CB-CG1 3.9Å; L62-V156 HydrophobicContact CB-CG2 4.4Å; L62-V156 HydrophobicContact CD1-CG1 4.07Å; L62-V156 HydrophobicContact CD1-CG2 3.97Å; L62-V156 HydrophobicContact CD2-CG1 3.96Å; L62-V156 HydrophobicContact CG-CG1 4.21Å
63	V	90.6	Very high	86.1	Confident	20 Å²	20	61.3 Å²	61.3	12%	0.121	34%	0.336	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.8	123.3	172.6	-178.7	0	0	0	0	108.9	L65 V80 K84 A85 L86 V87	V63-L65 HydrophobicContact CG1-CG 4.25Å; V63-L65 PolarHBondContact O-N 3.5Å; V63-V80 HydrophobicContact CG1-CG1 4.06Å; V63-K84 HydrophobicContact CG2-CB 3.93Å; V63-K84 HydrophobicContact CG2-CD 3.45Å; V63-K84 VanDerWaalsContact CG2-CD 3.45Å; V63-K84 HydrophobicContact CG2-CG 4.35Å; V63-A85 PolarHBondContact N-O 3.17Å; V63-L86 HydrophobicContact CB-CD1 4.08Å; V63-L86 HydrophobicContact CG1-CD1 4.21Å; V63-V87 PolarHBondContact O-N 3.37Å
64	N	90.3	Very high	85.8	Confident	58 Å²	58	63.1 Å²	63.1	31%	0.31	35%	0.351	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.7	112.9	173.8	-175.4	-0.2	0	0	0	110.1	T66 F143 E147	N64-T66 WeakPolarHBondContact OD1-CB 3.21Å; N64-T66 WeakPolarHBondContact OD1-CG2 3.3Å; N64-T66 PolarHBondContact OD1-N 3.29Å; N64-T66 PolarHBondContact OD1-OG1 3.09Å; N64-F143 HydrophobicContact CB-CZ 3.85Å; N64-F143 VanDerWaalsContact CG-CZ 3.45Å; N64-E147 PolarHBondContact ND2-OE1 3.37Å
65	L	87.9	Confident	85.3	Confident	27 Å²	27	64.8 Å²	64.8	14%	0.141	38%	0.38	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.7	32.6	167.2	-71.9	-174.6	0	0	0	111.2	V63 S67 T68 V76 V81 L86 V87 V88	V63-L65 HydrophobicContact CG1-CG 4.25Å; V63-L65 PolarHBondContact O-N 3.5Å; L65-S67 PolarHBondContact O-N 3.31Å; L65-T68 PolarHBondContact O-N 3.39Å; L65-T68 VanDerWaalsContact O-O 3.11Å; L65-T68 PolarHBondContact O-OG1 3.29Å; L65-V76 HydrophobicContact CD1-CG1 3.74Å; L65-V76 HydrophobicContact CD1-CG2 3.98Å; L65-V81 HydrophobicContact CD1-CG2 4.38Å; L65-L86 HydrophobicContact CB-CD1 4.14Å; L65-L86 HydrophobicContact CD1-CD1 3.26Å; L65-L86 HydrophobicContact CD1-CD2 4.08Å; L65-L86 HydrophobicContact CD1-CG 4.07Å; L65-L86 HydrophobicContact CG-CD1 3.67Å; L65-V87 CarbonylContact C-O 3.6Å; L65-V87 VanDerWaalsContact CA-O 3.29Å; L65-V87 WeakPolarHBondContact CA-O 3.32Å; L65-V87 WeakPolarHBondContact CB-O 3.46Å; L65-V87 PolarHBondContact N-O 3.48Å; L65-V88 HydrophobicContact CB-CG1 4.16Å
66	T	85.9	Confident	85.2	Confident	18 Å²	18	58.4 Å²	58.4	11%	0.11	35%	0.347	C	S	.	.	T	Hydrogen-bonded Turn	trans	-65	-15.4	178.4	55.6	0	0	0	0	113.8	N64 T68 V87 M89 A113 Y140 F143	N64-T66 WeakPolarHBondContact OD1-CB 3.21Å; N64-T66 WeakPolarHBondContact OD1-CG2 3.3Å; N64-T66 PolarHBondContact OD1-N 3.29Å; N64-T66 PolarHBondContact OD1-OG1 3.09Å; T66-T68 PolarHBondContact O-N 3.38Å; T66-V87 HydrophobicContact CG2-CB 4.42Å; T66-V87 HydrophobicContact CG2-CG1 3.8Å; T66-V87 PolarHBondContact N-O 3.47Å; T66-M89 HydrophobicContact CG2-CG 4.34Å; T66-M89 WeakPolarHBondContact O-CG 3.39Å; T66-A113 HydrophobicContact CG2-CB 4.4Å; T66-Y140 HydrophobicContact CG2-CD2 4.43Å; T66-Y140 HydrophobicContact CG2-CE2 4.02Å; T66-F143 HydrophobicContact CG2-CD1 3.72Å; T66-F143 HydrophobicContact CG2-CE1 3.47Å; T66-F143 VanDerWaalsContact CG2-CE1 3.47Å; T66-F143 HydrophobicContact CG2-CZ 4.13Å
67	S	83	Confident	85	Confident	112 Å²	112	60.6 Å²	60.6	78%	0.783	35%	0.351	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.1	-14.7	168	59.4	0	0	0	0	113.4	L65	L65-S67 PolarHBondContact O-N 3.31Å
68	T	83.7	Confident	84.9	Confident	41 Å²	41	63.9 Å²	63.9	25%	0.252	37%	0.372	S	S	.	.			trans	-118	150.3	-177.3	71.5	0	0	0	0	111.4	L65 T66 M89	L65-T68 PolarHBondContact O-N 3.39Å; L65-T68 VanDerWaalsContact O-O 3.11Å; L65-T68 PolarHBondContact O-OG1 3.29Å; T66-T68 PolarHBondContact O-N 3.38Å; T68-M89 PolarHBondContact O-N 2.86Å; T68-M89 VanDerWaalsContact O-N 3.12Å
69	V	84.1	Confident	84.7	Confident	57 Å²	57	67.8 Å²	67.8	35%	0.345	39%	0.385	S	S	.	.			trans	-93.5	-16.3	174.8	-174.2	0	0	0	0	111	C71 K98	V69-C71 VanDerWaalsContact CG1-SG 3.5Å; V69-C71 PolarHBondContact O-N 3.15Å; V69-K98 PolarHBondContact O-NZ 2.65Å
70	L	87.5	Confident	84.3	Confident	7 Å²	7	67.9 Å²	67.9	4%	0.037	39%	0.385	C	S	.	.			trans	54.9	49	-179.9	-160.7	76.4	0	0	0	113.6	V76 L86 V88 I101 A102 L105	L70-V76 HydrophobicContact CD1-CG2 4.16Å; L70-L86 HydrophobicContact CD2-CD2 3.78Å; L70-V88 HydrophobicContact CB-CB 4.34Å; L70-V88 HydrophobicContact CB-CG1 3.95Å; L70-V88 HydrophobicContact CD2-CG1 4.06Å; L70-I101 HydrophobicContact CD1-CG2 4.01Å; L70-I101 HydrophobicContact CD2-CG2 4.42Å; L70-I101 HydrophobicContact CG-CB 4.47Å; L70-I101 HydrophobicContact CG-CG2 3.96Å; L70-A102 HydrophobicContact CD2-CB 3.86Å; L70-L105 HydrophobicContact CD1-CD1 4.02Å
71	C	85.7	Confident	84	Confident	35 Å²	35	66 Å²	66	24%	0.236	38%	0.378	C	S	.	.	S	Bend	trans	-88.1	-18.3	170.1	-56.1	0	0	0	0	112.8	V69 C93 Q97 I101	V69-C71 VanDerWaalsContact CG1-SG 3.5Å; V69-C71 PolarHBondContact O-N 3.15Å; C71-C93 WeakPolarHBondContact CA-SG 3.39Å; C71-C93 HydrophobicContact CB-CB 3.71Å; C71-C93 WeakPolarHBondContact CB-SG 3.42Å; C71-C93 WeakPolarHBondContact SG-CB 3.31Å; C71-C93 CovalentContact SG-SG 2.04Å; C71-C93 PolarHBondContact SG-SG 3.49Å; C71-Q97 PolarHBondContact O-NE2 2.93Å; C71-Q97 VanDerWaalsContact O-NE2 3.07Å; C71-I101 WeakPolarHBondContact O-CD1 3.37Å
72	D	84.3	Confident	84	Confident	105 Å²	105	66.5 Å²	66.5	56%	0.561	38%	0.383	S	S	*	.	S	Bend	trans	-135.7	166.7	175.7	-67.1	-45.9	0	0	0	110.3	S74	D72-S74 PolarHBondContact O-N 2.92Å
73	D	79.1	Confident	83.9	Confident	81 Å²	81	67.9 Å²	67.9	43%	0.433	40%	0.399	S	S	.	.	S	Bend	trans	-82.3	1.3	175.9	55.3	0.1	0	0	0	113.7	G75 I101 K104 L105	D73-G75 PolarHBondContact O-N 3.15Å; D73-I101 HydrophobicContact CB-CG2 4.39Å; D73-K104 IonicContact OD2-NZ 3.8Å; D73-K104 PolarHBondContact OD2-NZ 2.69Å; D73-L105 HydrophobicContact CB-CD2 4.47Å
74	S	75.9	Confident	83.9	Confident	94 Å²	94	70 Å²	70	66%	0.657	41%	0.407	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.2	125.5	-179	56.9	0	0	0	0	111.9	D72	D72-S74 PolarHBondContact O-N 2.92Å
75	G	71.7	Confident	84	Confident	85 Å²	85	67.2 Å²	67.2	88%	0.876	39%	0.392	S	S	*	.	T	Hydrogen-bonded Turn	trans	94.3	-0.6	172	0	0	0	0	0	116.6	D73	D73-G75 PolarHBondContact O-N 3.15Å
76	V	81	Confident	84.2	Confident	17 Å²	17	66 Å²	66	10%	0.103	39%	0.386	C	S	.	.			trans	-113.4	123.6	178.4	-174.5	0	0	0	0	111	L65 L70 V81 L105	L65-V76 HydrophobicContact CD1-CG1 3.74Å; L65-V76 HydrophobicContact CD1-CG2 3.98Å; L70-V76 HydrophobicContact CD1-CG2 4.16Å; V76-V81 HydrophobicContact CG1-CG2 3.56Å; V76-L105 HydrophobicContact CB-CD1 4.1Å; V76-L105 HydrophobicContact CG1-CD1 4.08Å
77	R	81.9	Confident	84.5	Confident	184 Å²	184	65.1 Å²	65.1	69%	0.694	38%	0.38	S	S	*	.			trans	-81.3	126.6	176.8	-67.1	-175.4	-179.1	-178.8	1	110.6	E79 V80	R77-E79 VanDerWaalsContact C-N 3.26Å; R77-E79 PolarHBondContact O-N 3.15Å; R77-V80 HydrophobicContact CB-CG2 4.12Å; R77-V80 PolarHBondContact O-N 2.95Å; R77-V80 VanDerWaalsContact O-N 3.14Å
78	P	81.1	Confident	85	Confident	75 Å²	75	59.8 Å²	59.8	49%	0.487	34%	0.343	S	S	.	.	H	α-helix	trans	-57.4	-36.2	-179.3	-25.1	33.3	0	0	0	113.7	V80 V81 Q82 L105	P78-V80 PolarHBondContact O-N 2.96Å; P78-V80 VanDerWaalsContact O-N 3.16Å; P78-V81 PolarHBondContact O-N 3.39Å; P78-Q82 WeakPolarHBondContact O-CB 3.44Å; P78-Q82 PolarHBondContact O-N 3.02Å; P78-L105 HydrophobicContact CG-CD2 4.41Å
79	E	82.4	Confident	85.3	Confident	158 Å²	158	59.2 Å²	59.2	74%	0.738	34%	0.338	S	S	*	.	H	α-helix	trans	-56.9	-31.5	179.4	-64.2	167.6	-175.6	0	0	113.2	R77	R77-E79 VanDerWaalsContact C-N 3.26Å; R77-E79 PolarHBondContact O-N 3.15Å
80	V	82.3	Confident	85.6	Confident	68 Å²	68	59.8 Å²	59.8	41%	0.412	33%	0.334	S	S	.	.	H	α-helix	trans	-77	-30.6	-178	-179	0	0	0	0	110.9	V63 R77 P78 K84	V63-V80 HydrophobicContact CG1-CG1 4.06Å; R77-V80 HydrophobicContact CB-CG2 4.12Å; R77-V80 PolarHBondContact O-N 2.95Å; R77-V80 VanDerWaalsContact O-N 3.14Å; P78-V80 PolarHBondContact O-N 2.96Å; P78-V80 VanDerWaalsContact O-N 3.16Å; V80-K84 WeakPolarHBondContact O-CD 3.29Å; V80-K84 WeakPolarHBondContact O-CE 3.41Å; V80-K84 PolarHBondContact O-NZ 3.34Å
81	V	85	Confident	85.5	Confident	1 Å²	1	60.9 Å²	60.9	1%	0.006	35%	0.347	C	S	.	.	H	α-helix	trans	-103.2	-22.5	-167.7	-173.1	0	0	0	0	112.8	L65 V76 P78 G83 K84 L86 A107	L65-V81 HydrophobicContact CD1-CG2 4.38Å; V76-V81 HydrophobicContact CG1-CG2 3.56Å; P78-V81 PolarHBondContact O-N 3.39Å; V81-G83 PolarHBondContact O-N 3.16Å; V81-G83 VanDerWaalsContact O-N 3.16Å; V81-K84 PolarHBondContact O-N 2.9Å; V81-L86 HydrophobicContact CG1-CD1 4.02Å; V81-L86 HydrophobicContact CG1-CD2 4.47Å; V81-L86 HydrophobicContact CG2-CD1 4.19Å; V81-A107 HydrophobicContact CG1-CB 3.67Å
82	Q	89.8	Confident	85.4	Confident	141 Å²	141	69.2 Å²	69.2	66%	0.659	38%	0.382	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.5	120.1	-174.2	-167.1	172.7	13.7	0	0	112.4	P78 K84 G106	P78-Q82 WeakPolarHBondContact O-CB 3.44Å; P78-Q82 PolarHBondContact O-N 3.02Å; Q82-K84 VanDerWaalsContact C-N 3.28Å; Q82-K84 PolarHBondContact O-N 3.17Å; Q82-G106 WeakPolarHBondContact CA-O 3.12Å
83	G	88	Confident	85.6	Confident	41 Å²	41	65.2 Å²	65.2	42%	0.423	36%	0.362	S	S	.	.	T	Hydrogen-bonded Turn	trans	76.4	6.5	178.3	0	0	0	0	0	115.6	V81 G106	V81-G83 PolarHBondContact O-N 3.16Å; V81-G83 VanDerWaalsContact O-N 3.16Å; G83-G106 PolarHBondContact N-O 2.93Å
84	K	91.6	Very high	85.9	Confident	65 Å²	65	63.1 Å²	63.1	28%	0.283	36%	0.36	S	S	.	.	S	Bend	trans	-110.1	166.8	-175.5	-64.2	-175.1	-161.4	158.7	0	112.5	K61 V63 V80 V81 Q82 K108	K61-K84 HydrophobicContact CB-CD 4.28Å; K61-K84 HydrophobicContact CB-CG 4.28Å; K61-K84 WeakPolarHBondContact O-CB 3.02Å; V63-K84 HydrophobicContact CG2-CB 3.93Å; V63-K84 HydrophobicContact CG2-CD 3.45Å; V63-K84 VanDerWaalsContact CG2-CD 3.45Å; V63-K84 HydrophobicContact CG2-CG 4.35Å; V80-K84 WeakPolarHBondContact O-CD 3.29Å; V80-K84 WeakPolarHBondContact O-CE 3.41Å; V80-K84 PolarHBondContact O-NZ 3.34Å; V81-K84 PolarHBondContact O-N 2.9Å; Q82-K84 VanDerWaalsContact C-N 3.28Å; Q82-K84 PolarHBondContact O-N 3.17Å; K84-K108 PolarHBondContact O-N 3.39Å
85	A	91.8	Very high	86.6	Confident	0 Å²	0	60 Å²	60	0%	0	34%	0.335	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.9	137.2	170.4	0	0	0	0	0	109.6	Y60 K61 L62 V63 A109 V156	Y60-A85 HydrophobicContact CG-CB 4.17Å; K61-A85 PolarHBondContact O-N 2.9Å; L62-A85 CarbonylContact C-O 3.56Å; L62-A85 WeakPolarHBondContact CA-O 3.33Å; L62-A85 HydrophobicContact CD1-CB 3.98Å; V63-A85 PolarHBondContact N-O 3.17Å; A85-A109 WeakPolarHBondContact CA-O 3.45Å; A85-A109 HydrophobicContact CB-CB 4.06Å; A85-V156 HydrophobicContact CB-CG2 3.82Å
86	L	92.6	Very high	87.4	Confident	0 Å²	0	56.5 Å²	56.5	0%	0	30%	0.297	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.3	132.8	-174.2	-164.6	69.6	0	0	0	111.1	V63 L65 L70 V81 V88 A102 A109 L110 L111	V63-L86 HydrophobicContact CB-CD1 4.08Å; V63-L86 HydrophobicContact CG1-CD1 4.21Å; L65-L86 HydrophobicContact CB-CD1 4.14Å; L65-L86 HydrophobicContact CD1-CD1 3.26Å; L65-L86 HydrophobicContact CD1-CD2 4.08Å; L65-L86 HydrophobicContact CD1-CG 4.07Å; L65-L86 HydrophobicContact CG-CD1 3.67Å; L70-L86 HydrophobicContact CD2-CD2 3.78Å; V81-L86 HydrophobicContact CG1-CD1 4.02Å; V81-L86 HydrophobicContact CG1-CD2 4.47Å; V81-L86 HydrophobicContact CG2-CD1 4.19Å; L86-V88 HydrophobicContact CD2-CG1 3.7Å; L86-V88 HydrophobicContact CG-CG1 3.92Å; L86-A102 HydrophobicContact CD2-CB 4.31Å; L86-A109 PolarHBondContact N-O 2.84Å; L86-L110 HydrophobicContact CB-CD1 4.09Å; L86-L110 HydrophobicContact CD2-CD1 4.1Å; L86-L110 HydrophobicContact CG-CD1 4.42Å; L86-L111 PolarHBondContact O-N 2.86Å
87	V	92.4	Very high	87.9	Confident	0 Å²	0	59.9 Å²	59.9	0%	0	31%	0.311	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.8	125.4	167.5	-169.9	0	0	0	0	109.8	L62 V63 L65 T66 L111 A113 M138 F143	L62-V87 HydrophobicContact CD1-CG2 3.36Å; L62-V87 HydrophobicContact CD2-CG2 3.77Å; L62-V87 HydrophobicContact CG-CG2 3.64Å; V63-V87 PolarHBondContact O-N 3.37Å; L65-V87 CarbonylContact C-O 3.6Å; L65-V87 VanDerWaalsContact CA-O 3.29Å; L65-V87 WeakPolarHBondContact CA-O 3.32Å; L65-V87 WeakPolarHBondContact CB-O 3.46Å; L65-V87 PolarHBondContact N-O 3.48Å; T66-V87 HydrophobicContact CG2-CB 4.42Å; T66-V87 HydrophobicContact CG2-CG1 3.8Å; T66-V87 PolarHBondContact N-O 3.47Å; V87-L111 CarbonylContact C-O 3.57Å; V87-L111 VanDerWaalsContact CA-O 3.31Å; V87-L111 WeakPolarHBondContact CA-O 3.44Å; V87-L111 HydrophobicContact CB-CB 4.45Å; V87-L111 HydrophobicContact CG1-CB 4.43Å; V87-L111 HydrophobicContact CG2-CB 4Å; V87-L111 HydrophobicContact CG2-CD1 4.09Å; V87-A113 HydrophobicContact CG1-CB 4.04Å; V87-M138 HydrophobicContact CG1-CE 4.3Å; V87-M138 HydrophobicContact CG1-SD 4.21Å; V87-F143 HydrophobicContact CB-CE2 4.1Å; V87-F143 HydrophobicContact CB-CZ 4.41Å; V87-F143 HydrophobicContact CG1-CD2 4.04Å; V87-F143 HydrophobicContact CG1-CE2 4.06Å; V87-F143 HydrophobicContact CG1-CG 4.36Å; V87-F143 HydrophobicContact CG1-CZ 4.41Å; V87-F143 HydrophobicContact CG2-CD2 4.25Å; V87-F143 HydrophobicContact CG2-CE2 3.83Å
88	V	92.9	Very high	88.3	Confident	0 Å²	0	51.1 Å²	51.1	0%	0	28%	0.278	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.7	158.1	177.9	-59.8	0	0	0	0	111.1	L65 L70 L86 L110 L111 I112 A113	L65-V88 HydrophobicContact CB-CG1 4.16Å; L70-V88 HydrophobicContact CB-CB 4.34Å; L70-V88 HydrophobicContact CB-CG1 3.95Å; L70-V88 HydrophobicContact CD2-CG1 4.06Å; L86-V88 HydrophobicContact CD2-CG1 3.7Å; L86-V88 HydrophobicContact CG-CG1 3.92Å; V88-L110 HydrophobicContact CG1-CD1 4.3Å; V88-L110 HydrophobicContact CG2-CD1 3.86Å; V88-L111 PolarHBondContact N-O 2.87Å; V88-I112 HydrophobicContact CG2-CG1 4.07Å; V88-I112 CarbonylContact O-C 3.2Å; V88-I112 WeakPolarHBondContact O-CA 3.44Å; V88-A113 PolarHBondContact O-N 2.78Å
89	M	91	Very high	88.8	Confident	29 Å²	29	47.6 Å²	47.6	14%	0.143	26%	0.255	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-78.7	145.5	175.4	-79.2	-64.1	-79.9	0	0	112.4	T66 T68 K98 A113 Y140	T66-M89 HydrophobicContact CG2-CG 4.34Å; T66-M89 WeakPolarHBondContact O-CG 3.39Å; T68-M89 PolarHBondContact O-N 2.86Å; T68-M89 VanDerWaalsContact O-N 3.12Å; M89-K98 PolarHBondContact O-NZ 2.95Å; M89-A113 HydrophobicContact SD-CB 3.76Å; M89-Y140 HydrophobicContact CE-CD1 4.25Å; M89-Y140 HydrophobicContact CE-CD2 4.1Å; M89-Y140 HydrophobicContact CE-CE1 4.49Å; M89-Y140 HydrophobicContact CE-CE2 4.38Å; M89-Y140 HydrophobicContact CE-CG 4.01Å; M89-Y140 HydrophobicContact SD-CD2 3.32Å; M89-Y140 WeakPolarHBondContact SD-CD2 3.49Å; M89-Y140 HydrophobicContact SD-CE2 3.63Å; M89-Y140 HydrophobicContact SD-CG 3.81Å
90	R	89.4	Confident	89.2	Confident	69 Å²	69	43.3 Å²	43.3	26%	0.26	24%	0.237	S	C	.	.			trans	-63.1	138.1	166.8	-170.5	177.4	-176.6	176.5	4	108.9	I112 A113 S114 T116 T117	R90-I112 HydrophobicContact CB-CG2 3.92Å; R90-I112 HydrophobicContact CG-CG2 4.45Å; R90-A113 WeakPolarHBondContact CB-O 3.42Å; R90-A113 PolarHBondContact N-O 2.69Å; R90-S114 WeakPolarHBondContact CD-OG 2.98Å; R90-S114 PolarHBondContact NH1-OG 3.44Å; R90-T116 PolarHBondContact NH1-OG1 3.49Å; R90-T116 VanDerWaalsContact NH1-OG1 3.09Å; R90-T117 PolarHBondContact NH1-O 2.96Å
91	G	85.6	Confident	89.6	Confident	30 Å²	30	41.1 Å²	41.1	31%	0.309	22%	0.223	S	C	.	.			trans	-150.6	-155.2	170.9	0	0	0	0	0	109.6
92	E	84.6	Confident	89.9	Confident	210 Å²	210	41.1 Å²	41.1	98%	0.981	22%	0.222	S	C	*	.	S	Bend	trans	-83.5	-16.1	-167.8	-59.1	-174	167.3	0	0	114.3
93	C	87.6	Confident	90	Very high	21 Å²	21	37.2 Å²	37.2	14%	0.142	20%	0.204	C	C	.	.	S	Bend	trans	-78.7	150.4	175.7	57.7	0	0	0	0	112.9	C71 K98	C71-C93 WeakPolarHBondContact CA-SG 3.39Å; C71-C93 HydrophobicContact CB-CB 3.71Å; C71-C93 WeakPolarHBondContact CB-SG 3.42Å; C71-C93 WeakPolarHBondContact SG-CB 3.31Å; C71-C93 CovalentContact SG-SG 2.04Å; C71-C93 PolarHBondContact SG-SG 3.49Å; C93-K98 WeakPolarHBondContact O-CE 3.42Å; C93-K98 VanDerWaalsContact SG-CE 3.5Å
94	G	86.3	Confident	90.1	Very high	37 Å²	37	42.5 Å²	42.5	38%	0.381	22%	0.215	S	C	.	.			trans	-62.8	154.8	-175.7	0	0	0	0	0	114.3	S96 Q97 K98	G94-S96 PolarHBondContact O-N 3.02Å; G94-Q97 PolarHBondContact O-N 3.01Å; G94-K98 PolarHBondContact O-N 3.23Å
95	F	89.6	Confident	90.1	Very high	29 Å²	29	40.2 Å²	40.2	13%	0.127	21%	0.206	C	C	.	.	H	α-helix	trans	-60.9	-43.2	179.6	-64.2	-62.9	0	0	0	112.7	K98 A99 I112 P121 L135 L137	F95-K98 PolarHBondContact O-N 2.71Å; F95-A99 PolarHBondContact O-N 3.31Å; F95-A99 VanDerWaalsContact O-N 3.16Å; F95-I112 HydrophobicContact CD1-CD1 3.7Å; F95-I112 HydrophobicContact CE1-CD1 4.36Å; F95-P121 HydrophobicContact CB-CB 4.31Å; F95-P121 HydrophobicContact CD1-CB 4.28Å; F95-P121 HydrophobicContact CD2-CB 4.19Å; F95-P121 HydrophobicContact CG-CB 4.02Å; F95-L135 HydrophobicContact CB-CD2 4.17Å; F95-L137 HydrophobicContact CD1-CD1 4.15Å; F95-L137 HydrophobicContact CE1-CD1 3.9Å; F95-L137 HydrophobicContact CE1-CD2 3.81Å; F95-L137 HydrophobicContact CE1-CG 4.23Å; F95-L137 HydrophobicContact CZ-CD2 4.03Å
96	S	88.9	Confident	90	Very high	12 Å²	12	41.5 Å²	41.5	8%	0.084	22%	0.22	C	C	.	.	H	α-helix	trans	-61.8	-44.7	177.7	53.5	0	0	0	0	112.3	G94 K98 A99 I100 E127	G94-S96 PolarHBondContact O-N 3.02Å; S96-K98 PolarHBondContact O-N 3.31Å; S96-A99 PolarHBondContact O-N 3.28Å; S96-I100 VanDerWaalsContact O-CG1 3.29Å; S96-I100 WeakPolarHBondContact O-CG1 3.48Å; S96-I100 PolarHBondContact O-N 2.92Å; S96-E127 WeakPolarHBondContact CB-OE2 3.46Å; S96-E127 PolarHBondContact OG-OE2 3.1Å
97	Q	90.3	Very high	89.9	Confident	87 Å²	87	41.7 Å²	41.7	41%	0.407	22%	0.222	S	C	.	.	H	α-helix	trans	-58.9	-48.7	179.1	-178.1	178.4	-3.1	0	0	111.5	C71 G94 A99 I100 I101	C71-Q97 PolarHBondContact O-NE2 2.93Å; C71-Q97 VanDerWaalsContact O-NE2 3.07Å; G94-Q97 PolarHBondContact O-N 3.01Å; Q97-A99 VanDerWaalsContact C-N 3.3Å; Q97-A99 PolarHBondContact O-N 3.38Å; Q97-I100 PolarHBondContact O-N 3.38Å; Q97-I101 HydrophobicContact CG-CD1 4.04Å; Q97-I101 WeakPolarHBondContact O-CG1 3.39Å; Q97-I101 PolarHBondContact O-N 3.42Å; Q97-I101 VanDerWaalsContact O-N 3.09Å
98	K	91.4	Very high	89.9	Confident	1 Å²	1	47.4 Å²	47.4	0%	0.004	25%	0.246	C	C	.	.	H	α-helix	trans	-58.1	-43.7	176	-66.8	167.5	-178	-83.8	0	111.6	V69 M89 C93 G94 F95 S96 I101 A102 L110 I112	V69-K98 PolarHBondContact O-NZ 2.65Å; M89-K98 PolarHBondContact O-NZ 2.95Å; C93-K98 WeakPolarHBondContact O-CE 3.42Å; C93-K98 VanDerWaalsContact SG-CE 3.5Å; G94-K98 PolarHBondContact O-N 3.23Å; F95-K98 PolarHBondContact O-N 2.71Å; S96-K98 PolarHBondContact O-N 3.31Å; K98-I101 PolarHBondContact O-N 2.72Å; K98-A102 WeakPolarHBondContact O-CB 3.33Å; K98-A102 PolarHBondContact O-N 3.2Å; K98-L110 HydrophobicContact CB-CD2 4.02Å; K98-I112 HydrophobicContact CD-CD1 3.82Å
99	A	90.6	Very high	89.8	Confident	0 Å²	0	47.4 Å²	47.4	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-65.4	-40.8	-179.4	0	0	0	0	0	112.6	F95 S96 Q97 A102 Q103 L110 V131 L135	F95-A99 PolarHBondContact O-N 3.31Å; F95-A99 VanDerWaalsContact O-N 3.16Å; S96-A99 PolarHBondContact O-N 3.28Å; Q97-A99 VanDerWaalsContact C-N 3.3Å; Q97-A99 PolarHBondContact O-N 3.38Å; A99-A102 PolarHBondContact O-N 2.54Å; A99-Q103 VanDerWaalsContact O-CB 3.31Å; A99-Q103 WeakPolarHBondContact O-CB 3.28Å; A99-Q103 PolarHBondContact O-N 2.93Å; A99-L110 HydrophobicContact CB-CD2 4.05Å; A99-V131 HydrophobicContact CB-CB 4.4Å; A99-V131 HydrophobicContact CB-CG1 3.63Å; A99-V131 HydrophobicContact CB-CG2 3.8Å; A99-L135 HydrophobicContact CB-CD1 4.41Å; A99-L135 HydrophobicContact CB-CD2 4.35Å
100	I	91.3	Very high	90	Very high	69 Å²	69	46 Å²	46	35%	0.354	24%	0.239	S	C	.	.	H	α-helix	trans	-63.3	-43.2	176.1	-67.9	165.3	0	0	0	110.9	S96 Q97 Q103 K104 K130 V131	S96-I100 VanDerWaalsContact O-CG1 3.29Å; S96-I100 WeakPolarHBondContact O-CG1 3.48Å; S96-I100 PolarHBondContact O-N 2.92Å; Q97-I100 PolarHBondContact O-N 3.38Å; I100-Q103 PolarHBondContact O-N 2.98Å; I100-K104 WeakPolarHBondContact O-CB 3.44Å; I100-K104 PolarHBondContact O-N 2.95Å; I100-K130 HydrophobicContact CD1-CB 4.32Å; I100-V131 HydrophobicContact CG1-CG2 4.03Å
101	I	91.4	Very high	90.1	Very high	22 Å²	22	42.7 Å²	42.7	11%	0.113	23%	0.227	C	C	.	.	H	α-helix	trans	-66.1	-46.3	178.5	-65.1	165.4	0	0	0	110.6	L70 C71 D73 Q97 K98 Q103 K104 L105	L70-I101 HydrophobicContact CD1-CG2 4.01Å; L70-I101 HydrophobicContact CD2-CG2 4.42Å; L70-I101 HydrophobicContact CG-CB 4.47Å; L70-I101 HydrophobicContact CG-CG2 3.96Å; C71-I101 WeakPolarHBondContact O-CD1 3.37Å; D73-I101 HydrophobicContact CB-CG2 4.39Å; Q97-I101 HydrophobicContact CG-CD1 4.04Å; Q97-I101 WeakPolarHBondContact O-CG1 3.39Å; Q97-I101 PolarHBondContact O-N 3.42Å; Q97-I101 VanDerWaalsContact O-N 3.09Å; K98-I101 PolarHBondContact O-N 2.72Å; I101-Q103 VanDerWaalsContact C-N 3.29Å; I101-Q103 PolarHBondContact O-N 3.16Å; I101-K104 WeakPolarHBondContact O-CB 3.46Å; I101-K104 PolarHBondContact O-N 2.93Å; I101-K104 VanDerWaalsContact O-N 3.17Å; I101-L105 HydrophobicContact CG2-CD1 4.06Å; I101-L105 WeakPolarHBondContact O-CG 3.49Å; I101-L105 PolarHBondContact O-N 3.23Å
102	A	90.9	Very high	90.5	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-58.2	-43.1	176.4	0	0	0	0	0	111.8	L70 L86 K98 A99 L105 G106 A107 L110 I133	L70-A102 HydrophobicContact CD2-CB 3.86Å; L86-A102 HydrophobicContact CD2-CB 4.31Å; K98-A102 WeakPolarHBondContact O-CB 3.33Å; K98-A102 PolarHBondContact O-N 3.2Å; A99-A102 PolarHBondContact O-N 2.54Å; A102-L105 PolarHBondContact O-N 2.91Å; A102-G106 PolarHBondContact O-N 3.41Å; A102-A107 HydrophobicContact CB-CB 4.12Å; A102-A107 WeakPolarHBondContact O-CB 2.93Å; A102-A107 PolarHBondContact O-N 2.87Å; A102-L110 HydrophobicContact CB-CD1 4.12Å; A102-L110 HydrophobicContact CB-CD2 4.07Å; A102-L110 HydrophobicContact CB-CG 4.48Å; A102-I133 HydrophobicContact CB-CD1 3.96Å
103	Q	92	Very high	90.8	Very high	59 Å²	59	31.3 Å²	31.3	28%	0.276	17%	0.166	S	C	.	.	H	α-helix	trans	-63.7	-42.5	175.9	-177.2	176.6	-54.5	0	0	112	A99 I100 I101 L105 G106 I133	A99-Q103 VanDerWaalsContact O-CB 3.31Å; A99-Q103 WeakPolarHBondContact O-CB 3.28Å; A99-Q103 PolarHBondContact O-N 2.93Å; I100-Q103 PolarHBondContact O-N 2.98Å; I101-Q103 VanDerWaalsContact C-N 3.29Å; I101-Q103 PolarHBondContact O-N 3.16Å; Q103-L105 VanDerWaalsContact C-N 3.25Å; Q103-L105 PolarHBondContact O-N 3.03Å; Q103-G106 PolarHBondContact O-N 3.41Å; Q103-I133 HydrophobicContact CB-CD1 4.21Å; Q103-I133 HydrophobicContact CB-CG1 4.46Å; Q103-I133 HydrophobicContact CB-CG2 4.4Å; Q103-I133 HydrophobicContact CG-CG2 4.32Å
104	K	91.1	Very high	90.8	Very high	152 Å²	152	30.3 Å²	30.3	66%	0.661	16%	0.159	S	C	*	.	H	α-helix	trans	-60.4	-35.6	175.4	-174.2	-171	175	-162.2	0	111.8	D73 I100 I101 G106	D73-K104 IonicContact OD2-NZ 3.8Å; D73-K104 PolarHBondContact OD2-NZ 2.69Å; I100-K104 WeakPolarHBondContact O-CB 3.44Å; I100-K104 PolarHBondContact O-N 2.95Å; I101-K104 WeakPolarHBondContact O-CB 3.46Å; I101-K104 PolarHBondContact O-N 2.93Å; I101-K104 VanDerWaalsContact O-N 3.17Å; K104-G106 PolarHBondContact O-N 2.89Å
105	L	90.4	Very high	90.6	Very high	17 Å²	17	33.1 Å²	33.1	9%	0.089	17%	0.165	C	C	.	.	T	Hydrogen-bonded Turn	trans	-77.3	-2.1	175.8	-66.1	171	0	0	0	113.7	L70 D73 V76 P78 I101 A102 Q103	L70-L105 HydrophobicContact CD1-CD1 4.02Å; D73-L105 HydrophobicContact CB-CD2 4.47Å; V76-L105 HydrophobicContact CB-CD1 4.1Å; V76-L105 HydrophobicContact CG1-CD1 4.08Å; P78-L105 HydrophobicContact CG-CD2 4.41Å; I101-L105 HydrophobicContact CG2-CD1 4.06Å; I101-L105 WeakPolarHBondContact O-CG 3.49Å; I101-L105 PolarHBondContact O-N 3.23Å; A102-L105 PolarHBondContact O-N 2.91Å; Q103-L105 VanDerWaalsContact C-N 3.25Å; Q103-L105 PolarHBondContact O-N 3.03Å
106	G	89.9	Confident	89.9	Confident	28 Å²	28	35.6 Å²	35.6	29%	0.289	18%	0.183	S	C	.	.	T	Hydrogen-bonded Turn	trans	87.4	13.9	176.7	0	0	0	0	0	115.2	Q82 G83 A102 Q103 K104	Q82-G106 WeakPolarHBondContact CA-O 3.12Å; G83-G106 PolarHBondContact N-O 2.93Å; A102-G106 PolarHBondContact O-N 3.41Å; Q103-G106 PolarHBondContact O-N 3.41Å; K104-G106 PolarHBondContact O-N 2.89Å
107	A	91.3	Very high	88.9	Confident	4 Å²	4	37.7 Å²	37.7	3%	0.033	20%	0.195	C	C	.	.			trans	-64.5	151.2	172.2	0	0	0	0	0	111	V81 A102 I133	V81-A107 HydrophobicContact CG1-CB 3.67Å; A102-A107 HydrophobicContact CB-CB 4.12Å; A102-A107 WeakPolarHBondContact O-CB 2.93Å; A102-A107 PolarHBondContact O-N 2.87Å; A107-I133 WeakPolarHBondContact O-CG2 3.49Å
108	K	91.6	Very high	88.1	Confident	119 Å²	119	33.6 Å²	33.6	52%	0.517	18%	0.176	S	C	.	.	S	Bend	trans	-106	-18.8	177.3	-74.8	-70.4	-174.7	179.4	0	114.3	Y60 K84 P134	Y60-K108 HydrophobicContact CD1-CB 3.94Å; Y60-K108 HydrophobicContact CE1-CB 3.46Å; Y60-K108 VanDerWaalsContact CE1-CB 3.46Å; Y60-K108 HydrophobicContact CE1-CG 4.26Å; K84-K108 PolarHBondContact O-N 3.39Å; K108-P134 VanDerWaalsContact O-CD 3.3Å; K108-P134 WeakPolarHBondContact O-CD 3.23Å
109	A	91.9	Very high	87.4	Confident	0 Å²	0	34.9 Å²	34.9	0%	0	18%	0.184	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-150.2	148.2	173.8	0	0	0	0	0	109.8	Y60 A85 L86 L158	Y60-A109 HydrophobicContact CD2-CB 4.32Å; Y60-A109 HydrophobicContact CE2-CB 4.28Å; A85-A109 WeakPolarHBondContact CA-O 3.45Å; A85-A109 HydrophobicContact CB-CB 4.06Å; L86-A109 PolarHBondContact N-O 2.84Å; A109-L158 HydrophobicContact CB-CD1 4.22Å
110	L	93.4	Very high	86.9	Confident	0 Å²	0	34.9 Å²	34.9	0%	0	18%	0.184	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-123.9	125	178.8	-178.1	62.3	0	0	0	111.2	L86 V88 K98 A99 A102 I112 I133 P134 L135 A136	L86-L110 HydrophobicContact CB-CD1 4.09Å; L86-L110 HydrophobicContact CD2-CD1 4.1Å; L86-L110 HydrophobicContact CG-CD1 4.42Å; V88-L110 HydrophobicContact CG1-CD1 4.3Å; V88-L110 HydrophobicContact CG2-CD1 3.86Å; K98-L110 HydrophobicContact CB-CD2 4.02Å; A99-L110 HydrophobicContact CB-CD2 4.05Å; A102-L110 HydrophobicContact CB-CD1 4.12Å; A102-L110 HydrophobicContact CB-CD2 4.07Å; A102-L110 HydrophobicContact CB-CG 4.48Å; L110-I112 HydrophobicContact CD2-CD1 4.49Å; L110-I112 HydrophobicContact CD2-CG1 4.46Å; L110-I112 HydrophobicContact CG-CG1 4.28Å; L110-I133 HydrophobicContact CB-CD1 3.96Å; L110-P134 PolarHBondContact N-O 2.79Å; L110-L135 HydrophobicContact CB-CD1 4.03Å; L110-L135 HydrophobicContact CD2-CD1 3.72Å; L110-L135 HydrophobicContact CG-CD1 3.87Å; L110-L135 WeakPolarHBondContact O-CA 3.5Å; L110-A136 PolarHBondContact O-N 2.9Å; L110-A136 VanDerWaalsContact O-N 3.08Å
111	L	92.9	Very high	86.4	Confident	0 Å²	0	31.6 Å²	31.6	0%	0	17%	0.167	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-112.1	129	173.4	-71.8	168.7	0	0	0	109.5	L28 L41 L62 L86 V87 V88 A136 M138 L158	L28-L111 HydrophobicContact CD1-CD1 3.8Å; L28-L111 HydrophobicContact CD2-CD1 4.03Å; L41-L111 HydrophobicContact CD1-CD2 3.93Å; L41-L111 HydrophobicContact CD2-CD2 3.59Å; L41-L111 HydrophobicContact CG-CD2 4.42Å; L62-L111 HydrophobicContact CD1-CD1 3.81Å; L86-L111 PolarHBondContact O-N 2.86Å; V87-L111 CarbonylContact C-O 3.57Å; V87-L111 VanDerWaalsContact CA-O 3.31Å; V87-L111 WeakPolarHBondContact CA-O 3.44Å; V87-L111 HydrophobicContact CB-CB 4.45Å; V87-L111 HydrophobicContact CG1-CB 4.43Å; V87-L111 HydrophobicContact CG2-CB 4Å; V87-L111 HydrophobicContact CG2-CD1 4.09Å; V88-L111 PolarHBondContact N-O 2.87Å; L111-A136 CarbonylContact C-O 3.47Å; L111-A136 WeakPolarHBondContact CA-O 3.13Å; L111-A136 HydrophobicContact CD2-CB 4.02Å; L111-M138 HydrophobicContact CB-SD 3.91Å; L111-M138 HydrophobicContact CD1-SD 4.06Å; L111-M138 HydrophobicContact CD2-SD 4.23Å; L111-M138 HydrophobicContact CG-SD 4.3Å; L111-L158 HydrophobicContact CD2-CD2 3.84Å; L111-L158 HydrophobicContact CG-CD2 4.37Å
112	I	92.5	Very high	85.9	Confident	0 Å²	0	33.2 Å²	33.2	0%	0	18%	0.18	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-109.8	111.5	178.9	-60.8	175.9	0	0	0	108.6	V88 R90 F95 K98 L110 L135 A136 L137 M138	V88-I112 HydrophobicContact CG2-CG1 4.07Å; V88-I112 CarbonylContact O-C 3.2Å; V88-I112 WeakPolarHBondContact O-CA 3.44Å; R90-I112 HydrophobicContact CB-CG2 3.92Å; R90-I112 HydrophobicContact CG-CG2 4.45Å; F95-I112 HydrophobicContact CD1-CD1 3.7Å; F95-I112 HydrophobicContact CE1-CD1 4.36Å; K98-I112 HydrophobicContact CD-CD1 3.82Å; L110-I112 HydrophobicContact CD2-CD1 4.49Å; L110-I112 HydrophobicContact CD2-CG1 4.46Å; L110-I112 HydrophobicContact CG-CG1 4.28Å; I112-L135 HydrophobicContact CD1-CD1 3.75Å; I112-L135 HydrophobicContact CG1-CD1 4.21Å; I112-A136 PolarHBondContact N-O 3.41Å; I112-L137 HydrophobicContact CB-CD1 4.3Å; I112-L137 HydrophobicContact CB-CG 4.09Å; I112-L137 HydrophobicContact CD1-CD1 4.48Å; I112-L137 HydrophobicContact CG2-CG 4.4Å; I112-L137 CarbonylContact O-C 3.56Å; I112-L137 VanDerWaalsContact O-CA 3.3Å; I112-L137 WeakPolarHBondContact O-CA 3.4Å; I112-M138 PolarHBondContact O-N 3.35Å
113	A	91.3	Very high	85.5	Confident	0 Å²	0	34.3 Å²	34.3	0%	0	19%	0.189	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-80.1	127.9	175.1	0	0	0	0	0	110.6	T66 V87 V88 M89 R90 M138 Y140	T66-A113 HydrophobicContact CG2-CB 4.4Å; V87-A113 HydrophobicContact CG1-CB 4.04Å; V88-A113 PolarHBondContact O-N 2.78Å; M89-A113 HydrophobicContact SD-CB 3.76Å; R90-A113 WeakPolarHBondContact CB-O 3.42Å; R90-A113 PolarHBondContact N-O 2.69Å; A113-M138 CarbonylContact C-O 3.6Å; A113-M138 WeakPolarHBondContact CA-O 3.26Å; A113-M138 HydrophobicContact CB-CG 4.28Å; A113-Y140 HydrophobicContact CB-CD2 3.93Å
114	S	87.4	Confident	85.1	Confident	1 Å²	1	36.8 Å²	36.8	1%	0.007	20%	0.204	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-119.7	136.3	-178.5	-169.5	0	0	0	0	111.5	R90 T116 M138 Y140	R90-S114 WeakPolarHBondContact CD-OG 2.98Å; R90-S114 PolarHBondContact NH1-OG 3.44Å; S114-T116 WeakPolarHBondContact CB-O 3.48Å; S114-T116 PolarHBondContact OG-N 3.29Å; S114-T116 PolarHBondContact OG-O 3.44Å; S114-T116 PolarHBondContact OG-OG1 3.21Å; S114-M138 PolarHBondContact N-O 2.75Å; S114-Y140 PolarHBondContact O-N 2.72Å
115	N	83.7	Confident	84.5	Confident	96 Å²	96	38 Å²	38	51%	0.513	21%	0.212	S	C	.	.	S	Bend	trans	-87.7	-15.8	165.8	-78.9	-14.5	0	0	0	112.4	Y140 A391	N115-Y140 WeakPolarHBondContact OD1-CB 3.37Å; N115-Y140 WeakPolarHBondContact OD1-CD1 3.31Å; N115-A391 VanDerWaalsContact C-CB 3.47Å; N115-A391 WeakPolarHBondContact O-CB 3.15Å
116	T	74.5	Confident	84.1	Confident	80 Å²	80	40.9 Å²	40.9	49%	0.491	23%	0.234	S	C	.	.	S	Bend	trans	-107.9	167	178.4	58.5	0	0	0	0	110.9	R90 S114 L118 A391	R90-T116 PolarHBondContact NH1-OG1 3.49Å; R90-T116 VanDerWaalsContact NH1-OG1 3.09Å; S114-T116 WeakPolarHBondContact CB-O 3.48Å; S114-T116 PolarHBondContact OG-N 3.29Å; S114-T116 PolarHBondContact OG-O 3.44Å; S114-T116 PolarHBondContact OG-OG1 3.21Å; T116-L118 PolarHBondContact O-N 2.98Å; T116-A391 WeakPolarHBondContact O-CB 3.4Å
117	T	67.9	Low	83.8	Confident	57 Å²	57	41.9 Å²	41.9	35%	0.35	23%	0.231	S	C	.	.			trans	-38.4	123.7	179.9	51.9	0	0	0	0	112.1	R90 V119 I389 P390	R90-T117 PolarHBondContact NH1-O 2.96Å; T117-V119 PolarHBondContact O-N 3.38Å; T117-I389 CarbonylContact C-O 3.55Å; T117-I389 WeakPolarHBondContact CA-O 3.47Å; T117-P390 HydrophobicContact CG2-CB 4.25Å
118	L	73.3	Confident	83.3	Confident	0 Å²	0	43.6 Å²	43.6	0%	0	24%	0.237	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-65.5	121.9	170.8	-59.4	165.3	0	0	0	107	V42 T116 L137 M138 R139 E388 I389	V42-L118 HydrophobicContact CB-CB 4.48Å; V42-L118 HydrophobicContact CG2-CB 3.91Å; V42-L118 HydrophobicContact CG2-CD1 4.1Å; T116-L118 PolarHBondContact O-N 2.98Å; L118-L137 HydrophobicContact CD2-CB 3.81Å; L118-L137 HydrophobicContact CD2-CD2 4.48Å; L118-M138 VanDerWaalsContact CD2-C 3.49Å; L118-R139 HydrophobicContact CD1-CG 3.6Å; L118-R139 HydrophobicContact CG-CG 4.25Å; L118-E388 CarbonylContact O-C 3.52Å; L118-E388 VanDerWaalsContact O-CA 3.29Å; L118-E388 WeakPolarHBondContact O-CA 3.3Å; L118-I389 HydrophobicContact CB-CB 4.09Å; L118-I389 WeakPolarHBondContact CB-O 3.42Å; L118-I389 HydrophobicContact CD1-CB 4.06Å; L118-I389 HydrophobicContact CD1-CG2 4.09Å; L118-I389 PolarHBondContact N-O 2.76Å; L118-I389 PolarHBondContact O-N 3.44Å
119	V	76.9	Confident	83	Confident	28 Å²	28	42.6 Å²	42.6	17%	0.17	24%	0.243	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-116.7	145	174.6	-177.2	0	0	0	0	106.4	T117 P121 L137 E388	T117-V119 PolarHBondContact O-N 3.38Å; V119-P121 VanDerWaalsContact O-N 3.17Å; V119-L137 WeakPolarHBondContact O-CD2 3.46Å; V119-E388 HydrophobicContact CG2-CG 4.31Å
120	T	79.8	Confident	82.7	Confident	1 Å²	1	48.2 Å²	48.2	1%	0.006	27%	0.267	C	S	.	.			trans	-53.2	122.4	173.7	46.2	0	0	0	0	110.7	Q24 V42 S122 M386 V387	Q24-T120 HydrophobicContact CB-CG2 3.81Å; Q24-T120 HydrophobicContact CG-CG2 4.3Å; Q24-T120 VanDerWaalsContact OE1-CG2 3.26Å; V42-T120 HydrophobicContact CG1-CG2 3.64Å; T120-S122 PolarHBondContact O-N 3.08Å; T120-M386 WeakPolarHBondContact OG1-CA 3.29Å; T120-M386 WeakPolarHBondContact OG1-CB 3.27Å; T120-V387 HydrophobicContact CG2-CB 3.87Å; T120-V387 HydrophobicContact CG2-CG2 4.41Å; T120-V387 PolarHBondContact N-O 3.27Å
121	P	80.4	Confident	82.4	Confident	0 Å²	0	48.4 Å²	48.4	0%	0	27%	0.269	C	S	.	.			trans	-64.3	108.7	-175.7	22.3	-28.9	0	0	0	109	N44 W47 F95 V119 L135 L137	N44-P121 HydrophobicContact CB-CG 4.1Å; N44-P121 VanDerWaalsContact CB-O 3.23Å; N44-P121 WeakPolarHBondContact CB-O 3.37Å; N44-P121 PolarHBondContact ND2-O 3.01Å; W47-P121 PolarHBondContact NE1-O 2.9Å; F95-P121 HydrophobicContact CB-CB 4.31Å; F95-P121 HydrophobicContact CD1-CB 4.28Å; F95-P121 HydrophobicContact CD2-CB 4.19Å; F95-P121 HydrophobicContact CG-CB 4.02Å; V119-P121 VanDerWaalsContact O-N 3.17Å; P121-L135 HydrophobicContact CB-CD2 4.12Å; P121-L135 HydrophobicContact CB-CG 4.49Å; P121-L137 HydrophobicContact CB-CD1 3.65Å; P121-L137 HydrophobicContact CG-CD1 3.75Å
122	S	80.4	Confident	82.2	Confident	55 Å²	55	54.4 Å²	54.4	39%	0.385	30%	0.3	S	S	.	.			trans	-112.4	149.5	179.7	59.6	0	0	0	0	110.4	T120	T120-S122 PolarHBondContact O-N 3.08Å
123	A	82.2	Confident	82.2	Confident	23 Å²	23	54.8 Å²	54.8	19%	0.19	30%	0.302	C	S	.	.			trans	-143.3	174.6	170.5	0	0	0	0	0	109.3	W47 E127 Y128	W47-A123 HydrophobicContact CH2-CB 3.46Å; W47-A123 VanDerWaalsContact CH2-CB 3.46Å; W47-A123 HydrophobicContact CZ2-CB 3.46Å; W47-A123 VanDerWaalsContact CZ2-CB 3.46Å; A123-E127 HydrophobicContact CB-CB 4.06Å; A123-Y128 PolarHBondContact N-OH 2.92Å; A123-Y128 VanDerWaalsContact N-OH 3.14Å; A123-Y128 VanDerWaalsContact O-CE2 3.27Å; A123-Y128 WeakPolarHBondContact O-CE2 3.49Å; A123-Y128 PolarHBondContact O-OH 3.34Å; A123-Y128 VanDerWaalsContact O-OH 3.04Å
124	N	83.6	Confident	82.1	Confident	111 Å²	111	55.7 Å²	55.7	59%	0.594	31%	0.308	S	S	*	.			trans	-61.2	147.4	171.5	-69.4	-32.9	0	0	0	110.5	S126 E127	N124-S126 PolarHBondContact O-N 3.36Å; N124-E127 HydrophobicContact CB-CG 4.32Å; N124-E127 WeakPolarHBondContact O-CB 3.39Å; N124-E127 PolarHBondContact O-N 3.41Å
125	E	78.5	Confident	82.3	Confident	177 Å²	177	55.8 Å²	55.8	83%	0.827	31%	0.308	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.2	-31.8	-177	-70.4	-165.5	166.7	0	0	113.6	E127	E125-E127 PolarHBondContact O-N 3.04Å
126	S	83.2	Confident	82.6	Confident	79 Å²	79	51.2 Å²	51.2	55%	0.552	28%	0.284	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.8	-9.8	178.3	59.4	0	0	0	0	114.8	N124 K130	N124-S126 PolarHBondContact O-N 3.36Å; S126-K130 WeakPolarHBondContact O-CE 3.29Å
127	E	82.4	Confident	83.4	Confident	48 Å²	48	47.4 Å²	47.4	22%	0.224	26%	0.261	C	S	.	.	T	Hydrogen-bonded Turn	trans	-100.6	-26.1	-176.7	-65.8	-179.9	-169.7	0	0	113.5	S96 A123 N124 E125 K130	S96-E127 WeakPolarHBondContact CB-OE2 3.46Å; S96-E127 PolarHBondContact OG-OE2 3.1Å; A123-E127 HydrophobicContact CB-CB 4.06Å; N124-E127 HydrophobicContact CB-CG 4.32Å; N124-E127 WeakPolarHBondContact O-CB 3.39Å; N124-E127 PolarHBondContact O-N 3.41Å; E125-E127 PolarHBondContact O-N 3.04Å; E127-K130 WeakPolarHBondContact O-CB 3.49Å; E127-K130 PolarHBondContact O-N 3.37Å; E127-K130 VanDerWaalsContact O-N 3.1Å
128	Y	82.3	Confident	84.4	Confident	41 Å²	41	44.9 Å²	44.9	16%	0.161	25%	0.245	C	C	.	.	G	3₁₀ helix	trans	-50.1	-49.7	174.7	-66.1	-72.4	0	0	0	114.1	N44 W47 A123 K130 V131	N44-Y128 PolarHBondContact ND2-OH 3.2Å; W47-Y128 AromaticContact CD2-CD1 3.5Å; W47-Y128 HydrophobicContact CD2-CD1 3.5Å; W47-Y128 AromaticContact CD2-CE1 3.85Å; W47-Y128 HydrophobicContact CD2-CE1 3.85Å; W47-Y128 AromaticContact CE2-CD1 3.54Å; W47-Y128 AromaticContact CE2-CE1 3.4Å; W47-Y128 VanDerWaalsContact CE2-CE1 3.4Å; W47-Y128 AromaticContact CE3-CD1 3.63Å; W47-Y128 HydrophobicContact CE3-CD1 3.63Å; W47-Y128 HydrophobicContact CE3-CE1 4.36Å; W47-Y128 HydrophobicContact CE3-CG 4.46Å; W47-Y128 HydrophobicContact CG-CD1 4.11Å; W47-Y128 HydrophobicContact CG-CE1 4.32Å; W47-Y128 AromaticContact CH2-CD1 3.83Å; W47-Y128 HydrophobicContact CH2-CD1 3.83Å; W47-Y128 HydrophobicContact CH2-CE1 4.1Å; W47-Y128 HydrophobicContact CH2-CG 4.49Å; W47-Y128 AromaticContact CZ2-CD1 3.72Å; W47-Y128 HydrophobicContact CZ2-CD1 3.72Å; W47-Y128 AromaticContact CZ2-CE1 3.55Å; W47-Y128 HydrophobicContact CZ2-CE1 3.55Å; W47-Y128 AromaticContact CZ3-CD1 3.8Å; W47-Y128 HydrophobicContact CZ3-CD1 3.8Å; W47-Y128 HydrophobicContact CZ3-CE1 4.48Å; W47-Y128 HydrophobicContact CZ3-CG 4.38Å; W47-Y128 AromaticContact NE1-CE1 3.65Å; A123-Y128 PolarHBondContact N-OH 2.92Å; A123-Y128 VanDerWaalsContact N-OH 3.14Å; A123-Y128 VanDerWaalsContact O-CE2 3.27Å; A123-Y128 WeakPolarHBondContact O-CE2 3.49Å; A123-Y128 PolarHBondContact O-OH 3.34Å; A123-Y128 VanDerWaalsContact O-OH 3.04Å; Y128-K130 PolarHBondContact O-N 3.07Å; Y128-K130 VanDerWaalsContact O-N 3.1Å; Y128-V131 PolarHBondContact O-N 3.27Å
129	P	83.9	Confident	85	Confident	98 Å²	98	47.5 Å²	47.5	64%	0.636	26%	0.255	S	S	*	.	G	3₁₀ helix	trans	-68.9	-11.4	-177.2	26.2	-34.6	0	0	0	114.1
130	K	86.3	Confident	85.6	Confident	117 Å²	117	49 Å²	49	51%	0.509	26%	0.258	S	S	.	.	G	3₁₀ helix	trans	-81.3	-19	179.9	-59.8	177.7	-175.3	168.1	0	112.7	I100 S126 E127 Y128	I100-K130 HydrophobicContact CD1-CB 4.32Å; S126-K130 WeakPolarHBondContact O-CE 3.29Å; E127-K130 WeakPolarHBondContact O-CB 3.49Å; E127-K130 PolarHBondContact O-N 3.37Å; E127-K130 VanDerWaalsContact O-N 3.1Å; Y128-K130 PolarHBondContact O-N 3.07Å; Y128-K130 VanDerWaalsContact O-N 3.1Å
131	V	87.1	Confident	85.8	Confident	5 Å²	5	57.5 Å²	57.5	3%	0.03	29%	0.29	C	S	.	.			trans	-104.9	117.6	-176.4	177.5	0	0	0	0	109.3	W47 T48 A99 I100 Y128 I133	W47-V131 HydrophobicContact CE3-CB 3.66Å; W47-V131 HydrophobicContact CE3-CG1 4.01Å; W47-V131 HydrophobicContact CE3-CG2 4.04Å; W47-V131 HydrophobicContact CH2-CG2 4.31Å; W47-V131 HydrophobicContact CZ3-CB 3.6Å; W47-V131 HydrophobicContact CZ3-CG1 4.28Å; W47-V131 HydrophobicContact CZ3-CG2 3.46Å; W47-V131 VanDerWaalsContact CZ3-CG2 3.46Å; T48-V131 PolarHBondContact OG1-O 2.63Å; A99-V131 HydrophobicContact CB-CB 4.4Å; A99-V131 HydrophobicContact CB-CG1 3.63Å; A99-V131 HydrophobicContact CB-CG2 3.8Å; I100-V131 HydrophobicContact CG1-CG2 4.03Å; Y128-V131 PolarHBondContact O-N 3.27Å; V131-I133 HydrophobicContact CG1-CG1 4.14Å; V131-I133 WeakPolarHBondContact CG1-O 3.36Å
132	L	88.9	Confident	86.1	Confident	125 Å²	125	59.2 Å²	59.2	65%	0.654	30%	0.299	S	S	*	.			trans	-107.3	-1.6	-176.7	-61.1	171.2	0	0	0	113	T48	T48-L132 WeakPolarHBondContact OG1-CA 3.21Å; T48-L132 PolarHBondContact OG1-O 3.48Å
133	I	91.2	Very high	86.5	Confident	9 Å²	9	56.6 Å²	56.6	5%	0.046	28%	0.281	C	S	.	.	S	Bend	trans	-104.8	143.7	178.2	61.3	171.6	0	0	0	110.3	T48 A102 Q103 A107 L110 V131 L135	T48-I133 PolarHBondContact OG1-N 2.83Å; T48-I133 PolarHBondContact OG1-O 2.78Å; A102-I133 HydrophobicContact CB-CD1 3.96Å; Q103-I133 HydrophobicContact CB-CD1 4.21Å; Q103-I133 HydrophobicContact CB-CG1 4.46Å; Q103-I133 HydrophobicContact CB-CG2 4.4Å; Q103-I133 HydrophobicContact CG-CG2 4.32Å; A107-I133 WeakPolarHBondContact O-CG2 3.49Å; L110-I133 HydrophobicContact CB-CD1 3.96Å; V131-I133 HydrophobicContact CG1-CG1 4.14Å; V131-I133 WeakPolarHBondContact CG1-O 3.36Å; I133-L135 PolarHBondContact O-N 3.41Å
134	P	91	Very high	86.8	Confident	18 Å²	18	57.6 Å²	57.6	12%	0.117	28%	0.282	C	S	.	.			trans	-59.4	134.4	172.7	-22.9	34	0	0	0	111.5	T48 L50 K108 L110	T48-P134 HydrophobicContact CG2-CG 4.29Å; L50-P134 HydrophobicContact CD2-CB 3.66Å; L50-P134 HydrophobicContact CD2-CG 4.23Å; K108-P134 VanDerWaalsContact O-CD 3.3Å; K108-P134 WeakPolarHBondContact O-CD 3.23Å; L110-P134 PolarHBondContact N-O 2.79Å
135	L	90.8	Very high	87	Confident	4 Å²	4	53.9 Å²	53.9	2%	0.021	27%	0.265	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.7	121.2	-177.7	178.3	65.5	0	0	0	109.9	W47 F95 A99 L110 I112 P121 I133	W47-L135 HydrophobicContact CD2-CD2 4.31Å; W47-L135 HydrophobicContact CZ2-CD2 4.39Å; F95-L135 HydrophobicContact CB-CD2 4.17Å; A99-L135 HydrophobicContact CB-CD1 4.41Å; A99-L135 HydrophobicContact CB-CD2 4.35Å; L110-L135 HydrophobicContact CB-CD1 4.03Å; L110-L135 HydrophobicContact CD2-CD1 3.72Å; L110-L135 HydrophobicContact CG-CD1 3.87Å; L110-L135 WeakPolarHBondContact O-CA 3.5Å; I112-L135 HydrophobicContact CD1-CD1 3.75Å; I112-L135 HydrophobicContact CG1-CD1 4.21Å; P121-L135 HydrophobicContact CB-CD2 4.12Å; P121-L135 HydrophobicContact CB-CG 4.49Å; I133-L135 PolarHBondContact O-N 3.41Å
136	A	91.1	Very high	87.4	Confident	0 Å²	0	45.5 Å²	45.5	0%	0	23%	0.226	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-142.2	155.4	176.9	0	0	0	0	0	112.4	L41 V42 F43 L110 L111 I112	L41-A136 HydrophobicContact CB-CB 4.12Å; L41-A136 HydrophobicContact CD1-CB 3.99Å; L41-A136 HydrophobicContact CD2-CB 4.46Å; L41-A136 HydrophobicContact CG-CB 4.44Å; V42-A136 CarbonylContact O-C 3.55Å; V42-A136 WeakPolarHBondContact O-CA 3.27Å; F43-A136 HydrophobicContact CB-CB 4.02Å; L110-A136 PolarHBondContact O-N 2.9Å; L110-A136 VanDerWaalsContact O-N 3.08Å; L111-A136 CarbonylContact C-O 3.47Å; L111-A136 WeakPolarHBondContact CA-O 3.13Å; L111-A136 HydrophobicContact CD2-CB 4.02Å; I112-A136 PolarHBondContact N-O 3.41Å
137	L	89.9	Confident	87.6	Confident	0 Å²	0	44.9 Å²	44.9	0%	0	22%	0.215	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-106	146.7	177.1	-84.3	70.6	0	0	0	110.5	L41 V42 F95 I112 L118 V119 P121	L41-L137 CarbonylContact C-O 3.57Å; L41-L137 VanDerWaalsContact CA-O 3.26Å; L41-L137 WeakPolarHBondContact CA-O 3.42Å; V42-L137 HydrophobicContact CB-CB 4.47Å; V42-L137 PolarHBondContact N-O 2.79Å; V42-L137 PolarHBondContact O-N 3.33Å; F95-L137 HydrophobicContact CD1-CD1 4.15Å; F95-L137 HydrophobicContact CE1-CD1 3.9Å; F95-L137 HydrophobicContact CE1-CD2 3.81Å; F95-L137 HydrophobicContact CE1-CG 4.23Å; F95-L137 HydrophobicContact CZ-CD2 4.03Å; I112-L137 HydrophobicContact CB-CD1 4.3Å; I112-L137 HydrophobicContact CB-CG 4.09Å; I112-L137 HydrophobicContact CD1-CD1 4.48Å; I112-L137 HydrophobicContact CG2-CG 4.4Å; I112-L137 CarbonylContact O-C 3.56Å; I112-L137 VanDerWaalsContact O-CA 3.3Å; I112-L137 WeakPolarHBondContact O-CA 3.4Å; L118-L137 HydrophobicContact CD2-CB 3.81Å; L118-L137 HydrophobicContact CD2-CD2 4.48Å; V119-L137 WeakPolarHBondContact O-CD2 3.46Å; P121-L137 HydrophobicContact CB-CD1 3.65Å; P121-L137 HydrophobicContact CG-CD1 3.75Å
138	M	89.2	Confident	87.9	Confident	4 Å²	4	52 Å²	52	2%	0.02	24%	0.24	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-139.7	156	177.7	58.1	-169.6	-96.7	0	0	111.4	L28 L41 V87 L111 I112 A113 S114 L118 F143	L28-M138 HydrophobicContact CD2-CE 4.44Å; L28-M138 HydrophobicContact CD2-SD 4.11Å; L41-M138 HydrophobicContact CD2-CB 3.66Å; L41-M138 HydrophobicContact CD2-SD 4.49Å; V87-M138 HydrophobicContact CG1-CE 4.3Å; V87-M138 HydrophobicContact CG1-SD 4.21Å; L111-M138 HydrophobicContact CB-SD 3.91Å; L111-M138 HydrophobicContact CD1-SD 4.06Å; L111-M138 HydrophobicContact CD2-SD 4.23Å; L111-M138 HydrophobicContact CG-SD 4.3Å; I112-M138 PolarHBondContact O-N 3.35Å; A113-M138 CarbonylContact C-O 3.6Å; A113-M138 WeakPolarHBondContact CA-O 3.26Å; A113-M138 HydrophobicContact CB-CG 4.28Å; S114-M138 PolarHBondContact N-O 2.75Å; L118-M138 VanDerWaalsContact CD2-C 3.49Å; M138-F143 HydrophobicContact CE-CB 3.23Å; M138-F143 HydrophobicContact CE-CD2 3.33Å; M138-F143 HydrophobicContact CE-CE2 4.49Å; M138-F143 HydrophobicContact CE-CG 3.61Å
139	R	86.7	Confident	88.1	Confident	55 Å²	55	52.8 Å²	52.8	21%	0.208	25%	0.248	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-71.6	136	173.9	-55.7	-172.6	-177.7	-171.8	7	109.6	L118 R141 D142 F143 P390	L118-R139 HydrophobicContact CD1-CG 3.6Å; L118-R139 HydrophobicContact CG-CG 4.25Å; R139-R141 VanDerWaalsContact C-N 3.28Å; R139-R141 PolarHBondContact O-N 3.26Å; R139-D142 HydrophobicContact CB-CB 4.22Å; R139-D142 WeakPolarHBondContact CB-OD2 3.46Å; R139-D142 WeakPolarHBondContact O-CB 3.23Å; R139-D142 PolarHBondContact O-N 2.81Å; R139-D142 VanDerWaalsContact O-N 3.15Å; R139-F143 PolarHBondContact O-N 3.18Å; R139-F143 VanDerWaalsContact O-N 3.15Å; R139-P390 PolarHBondContact NE-O 3.47Å; R139-P390 PolarHBondContact NH1-O 2.83Å; R139-P390 PolarHBondContact NH2-O 3.3Å; R139-P390 VanDerWaalsContact NH2-O 3.17Å
140	Y	87.8	Confident	88.2	Confident	59 Å²	59	48.6 Å²	48.6	23%	0.231	22%	0.22	C	C	.	.	H	α-helix	trans	-64.3	-33.2	177.7	-177.5	-121.1	0	0	0	112.7	T66 M89 A113 S114 N115 D142 F143 L144	T66-Y140 HydrophobicContact CG2-CD2 4.43Å; T66-Y140 HydrophobicContact CG2-CE2 4.02Å; M89-Y140 HydrophobicContact CE-CD1 4.25Å; M89-Y140 HydrophobicContact CE-CD2 4.1Å; M89-Y140 HydrophobicContact CE-CE1 4.49Å; M89-Y140 HydrophobicContact CE-CE2 4.38Å; M89-Y140 HydrophobicContact CE-CG 4.01Å; M89-Y140 HydrophobicContact SD-CD2 3.32Å; M89-Y140 WeakPolarHBondContact SD-CD2 3.49Å; M89-Y140 HydrophobicContact SD-CE2 3.63Å; M89-Y140 HydrophobicContact SD-CG 3.81Å; A113-Y140 HydrophobicContact CB-CD2 3.93Å; S114-Y140 PolarHBondContact O-N 2.72Å; N115-Y140 WeakPolarHBondContact OD1-CB 3.37Å; N115-Y140 WeakPolarHBondContact OD1-CD1 3.31Å; Y140-D142 VanDerWaalsContact C-N 3.3Å; Y140-D142 PolarHBondContact O-N 3.29Å; Y140-F143 HydrophobicContact CD2-CB 4.48Å; Y140-F143 HydrophobicContact CD2-CD1 4.25Å; Y140-F143 HydrophobicContact CE2-CD1 4.11Å; Y140-F143 VanDerWaalsContact O-CB 3.28Å; Y140-F143 WeakPolarHBondContact O-CB 3.36Å; Y140-F143 PolarHBondContact O-N 3.07Å; Y140-L144 HydrophobicContact CD1-CD1 3.88Å; Y140-L144 HydrophobicContact CD1-CG 4.31Å; Y140-L144 HydrophobicContact CE1-CD1 3.57Å; Y140-L144 HydrophobicContact CE1-CD2 4.31Å; Y140-L144 HydrophobicContact CE1-CG 4.01Å; Y140-L144 HydrophobicContact CE2-CD2 4.26Å; Y140-L144 HydrophobicContact CE2-CG 4.24Å; Y140-L144 WeakPolarHBondContact O-CG 3.34Å; Y140-L144 PolarHBondContact O-N 2.91Å
141	R	84.4	Confident	88.1	Confident	179 Å²	179	44.5 Å²	44.5	68%	0.675	21%	0.211	S	C	*	.	H	α-helix	trans	-60.4	-40.7	173.5	177.7	178.4	165.7	166	-3.2	112.2	R139 F143 L144 S145	R139-R141 VanDerWaalsContact C-N 3.28Å; R139-R141 PolarHBondContact O-N 3.26Å; R141-F143 VanDerWaalsContact C-N 3.33Å; R141-L144 PolarHBondContact O-N 3.29Å; R141-S145 WeakPolarHBondContact O-CB 3.4Å; R141-S145 PolarHBondContact O-N 2.95Å
142	D	86.4	Confident	87.5	Confident	36 Å²	36	53.7 Å²	53.7	19%	0.193	25%	0.254	C	S	.	.	H	α-helix	trans	-66.5	-41.3	179.6	-66.4	-13.2	0	0	0	109.8	Y39 R139 Y140 S145 A146	Y39-D142 HydrophobicContact CD1-CB 3.76Å; Y39-D142 HydrophobicContact CE1-CB 4.35Å; R139-D142 HydrophobicContact CB-CB 4.22Å; R139-D142 WeakPolarHBondContact CB-OD2 3.46Å; R139-D142 WeakPolarHBondContact O-CB 3.23Å; R139-D142 PolarHBondContact O-N 2.81Å; R139-D142 VanDerWaalsContact O-N 3.15Å; Y140-D142 VanDerWaalsContact C-N 3.3Å; Y140-D142 PolarHBondContact O-N 3.29Å; D142-S145 PolarHBondContact O-N 2.96Å; D142-S145 PolarHBondContact O-OG 3.27Å; D142-A146 PolarHBondContact O-N 3.17Å
143	F	89.3	Confident	86.9	Confident	1 Å²	1	49.9 Å²	49.9	0%	0.004	24%	0.244	C	C	.	.	H	α-helix	trans	-54.8	-53.5	170	-173.4	-116.2	0	0	0	112.8	L62 N64 T66 V87 M138 R139 Y140 R141 S145 A146 E147	L62-F143 HydrophobicContact CD2-CE2 3.98Å; N64-F143 HydrophobicContact CB-CZ 3.85Å; N64-F143 VanDerWaalsContact CG-CZ 3.45Å; T66-F143 HydrophobicContact CG2-CD1 3.72Å; T66-F143 HydrophobicContact CG2-CE1 3.47Å; T66-F143 VanDerWaalsContact CG2-CE1 3.47Å; T66-F143 HydrophobicContact CG2-CZ 4.13Å; V87-F143 HydrophobicContact CB-CE2 4.1Å; V87-F143 HydrophobicContact CB-CZ 4.41Å; V87-F143 HydrophobicContact CG1-CD2 4.04Å; V87-F143 HydrophobicContact CG1-CE2 4.06Å; V87-F143 HydrophobicContact CG1-CG 4.36Å; V87-F143 HydrophobicContact CG1-CZ 4.41Å; V87-F143 HydrophobicContact CG2-CD2 4.25Å; V87-F143 HydrophobicContact CG2-CE2 3.83Å; M138-F143 HydrophobicContact CE-CB 3.23Å; M138-F143 HydrophobicContact CE-CD2 3.33Å; M138-F143 HydrophobicContact CE-CE2 4.49Å; M138-F143 HydrophobicContact CE-CG 3.61Å; R139-F143 PolarHBondContact O-N 3.18Å; R139-F143 VanDerWaalsContact O-N 3.15Å; Y140-F143 HydrophobicContact CD2-CB 4.48Å; Y140-F143 HydrophobicContact CD2-CD1 4.25Å; Y140-F143 HydrophobicContact CE2-CD1 4.11Å; Y140-F143 VanDerWaalsContact O-CB 3.28Å; Y140-F143 WeakPolarHBondContact O-CB 3.36Å; Y140-F143 PolarHBondContact O-N 3.07Å; R141-F143 VanDerWaalsContact C-N 3.33Å; F143-S145 PolarHBondContact O-N 2.84Å; F143-A146 WeakPolarHBondContact O-CA 3.12Å; F143-A146 WeakPolarHBondContact O-CB 3.35Å; F143-A146 PolarHBondContact O-N 3.26Å; F143-E147 PolarHBondContact O-N 3.23Å
144	L	89.3	Confident	86.8	Confident	43 Å²	43	49.8 Å²	49.8	23%	0.225	24%	0.244	C	C	.	.	H	α-helix	trans	-60.2	-35.2	179.9	-71	175.1	0	0	0	111.6	Y140 R141 R148	Y140-L144 HydrophobicContact CD1-CD1 3.88Å; Y140-L144 HydrophobicContact CD1-CG 4.31Å; Y140-L144 HydrophobicContact CE1-CD1 3.57Å; Y140-L144 HydrophobicContact CE1-CD2 4.31Å; Y140-L144 HydrophobicContact CE1-CG 4.01Å; Y140-L144 HydrophobicContact CE2-CD2 4.26Å; Y140-L144 HydrophobicContact CE2-CG 4.24Å; Y140-L144 WeakPolarHBondContact O-CG 3.34Å; Y140-L144 PolarHBondContact O-N 2.91Å; R141-L144 PolarHBondContact O-N 3.29Å; L144-R148 VanDerWaalsContact O-CG 3.26Å; L144-R148 WeakPolarHBondContact O-CG 3.47Å; L144-R148 PolarHBondContact O-N 3.04Å; L144-R148 VanDerWaalsContact O-N 3.12Å
145	S	86.9	Confident	86.8	Confident	33 Å²	33	52.6 Å²	52.6	23%	0.231	26%	0.256	C	S	.	.	H	α-helix	trans	-69	-36.9	175.7	79.9	0	0	0	0	112.3	Y39 R141 D142 F143 V149	Y39-S145 WeakPolarHBondContact CE1-OG 3.18Å; R141-S145 WeakPolarHBondContact O-CB 3.4Å; R141-S145 PolarHBondContact O-N 2.95Å; D142-S145 PolarHBondContact O-N 2.96Å; D142-S145 PolarHBondContact O-OG 3.27Å; F143-S145 PolarHBondContact O-N 2.84Å; S145-V149 VanDerWaalsContact O-CG2 3.25Å; S145-V149 WeakPolarHBondContact O-CG2 2.98Å; S145-V149 PolarHBondContact O-N 3.1Å
146	A	87	Confident	86.8	Confident	1 Å²	1	52.4 Å²	52.4	1%	0.008	26%	0.255	C	S	.	.	H	α-helix	trans	-66.5	-47	173.3	0	0	0	0	0	111.4	I30 Y39 D142 F143 R148 V149 F150 M154	I30-A146 HydrophobicContact CD1-CB 3.68Å; Y39-A146 HydrophobicContact CE1-CB 4.44Å; Y39-A146 HydrophobicContact CE2-CB 3.71Å; Y39-A146 VanDerWaalsContact OH-CA 3.3Å; Y39-A146 WeakPolarHBondContact OH-CA 2.99Å; Y39-A146 PolarHBondContact OH-N 2.82Å; D142-A146 PolarHBondContact O-N 3.17Å; F143-A146 WeakPolarHBondContact O-CA 3.12Å; F143-A146 WeakPolarHBondContact O-CB 3.35Å; F143-A146 PolarHBondContact O-N 3.26Å; A146-R148 VanDerWaalsContact C-N 3.33Å; A146-R148 PolarHBondContact O-N 3.14Å; A146-V149 PolarHBondContact O-N 3.1Å; A146-F150 HydrophobicContact CB-CD2 4.35Å; A146-F150 VanDerWaalsContact O-CD2 3.31Å; A146-F150 WeakPolarHBondContact O-CD2 2.99Å; A146-F150 PolarHBondContact O-N 3.05Å; A146-M154 HydrophobicContact CB-SD 4.26Å
147	E	88.8	Confident	86.8	Confident	67 Å²	67	54.8 Å²	54.8	31%	0.313	27%	0.265	S	S	.	.	H	α-helix	trans	-59.9	-42.3	-179.1	-175.1	172.6	-136.8	0	0	112	N64 F143 V149 G151 M154	N64-E147 PolarHBondContact ND2-OE1 3.37Å; F143-E147 PolarHBondContact O-N 3.23Å; E147-V149 PolarHBondContact O-N 2.89Å; E147-G151 WeakPolarHBondContact O-CA 3.38Å; E147-G151 PolarHBondContact O-N 3.32Å; E147-M154 HydrophobicContact CB-CE 4.18Å; E147-M154 HydrophobicContact CG-CE 4.34Å
148	R	88.4	Confident	86.8	Confident	198 Å²	198	55.2 Å²	55.2	75%	0.747	27%	0.267	S	S	*	.	H	α-helix	trans	-62.1	-28.2	175	-72.8	176.1	-154	153.5	4.9	113.9	L144 A146	L144-R148 VanDerWaalsContact O-CG 3.26Å; L144-R148 WeakPolarHBondContact O-CG 3.47Å; L144-R148 PolarHBondContact O-N 3.04Å; L144-R148 VanDerWaalsContact O-N 3.12Å; A146-R148 VanDerWaalsContact C-N 3.33Å; A146-R148 PolarHBondContact O-N 3.14Å
149	V	86.5	Confident	86.7	Confident	56 Å²	56	56 Å²	56	34%	0.339	27%	0.27	S	S	.	.	H	α-helix	trans	-92	-40.2	-176.1	174.4	0	0	0	0	111.5	S145 A146 E147	S145-V149 VanDerWaalsContact O-CG2 3.25Å; S145-V149 WeakPolarHBondContact O-CG2 2.98Å; S145-V149 PolarHBondContact O-N 3.1Å; A146-V149 PolarHBondContact O-N 3.1Å; E147-V149 PolarHBondContact O-N 2.89Å
150	F	85.5	Confident	86.6	Confident	10 Å²	10	54 Å²	54	4%	0.044	27%	0.265	C	S	.	.	H	α-helix	trans	-108.6	-19.1	-168.7	-64	-75.1	0	0	0	114.9	I30 N32 L35 R37 A146 M154	I30-F150 HydrophobicContact CB-CD2 4.4Å; I30-F150 HydrophobicContact CB-CE2 4.12Å; I30-F150 HydrophobicContact CB-CZ 4.45Å; I30-F150 HydrophobicContact CG2-CD1 4.41Å; I30-F150 HydrophobicContact CG2-CD2 3.74Å; I30-F150 HydrophobicContact CG2-CE2 3.92Å; I30-F150 HydrophobicContact CG2-CG 4Å; I30-F150 HydrophobicContact CG2-CZ 4.32Å; N32-F150 HydrophobicContact CB-CD1 3.81Å; N32-F150 HydrophobicContact CB-CE1 4.44Å; L35-F150 HydrophobicContact CB-CE1 3.82Å; L35-F150 WeakPolarHBondContact O-CE1 2.95Å; R37-F150 HydrophobicContact CB-CE2 3.82Å; R37-F150 HydrophobicContact CB-CZ 3.8Å; R37-F150 HydrophobicContact CG-CE2 4.02Å; R37-F150 HydrophobicContact CG-CZ 3.82Å; A146-F150 HydrophobicContact CB-CD2 4.35Å; A146-F150 VanDerWaalsContact O-CD2 3.31Å; A146-F150 WeakPolarHBondContact O-CD2 2.99Å; A146-F150 PolarHBondContact O-N 3.05Å; F150-M154 HydrophobicContact CB-CG 3.38Å; F150-M154 HydrophobicContact CB-SD 4.08Å; F150-M154 HydrophobicContact CG-CG 4.26Å
151	G	83.3	Confident	86	Confident	32 Å²	32	52.6 Å²	52.6	33%	0.33	26%	0.263	S	S	.	.	G	3₁₀ helix	trans	63.7	-154.1	-179.1	0	0	0	0	0	114	E147 G153 M154	E147-G151 WeakPolarHBondContact O-CA 3.38Å; E147-G151 PolarHBondContact O-N 3.32Å; G151-G153 VanDerWaalsContact C-N 3.28Å; G151-G153 PolarHBondContact O-N 2.7Å; G151-M154 WeakPolarHBondContact O-CE 3.49Å; G151-M154 WeakPolarHBondContact O-CG 3.29Å
152	E	75.6	Confident	85.1	Confident	198 Å²	198	48.4 Å²	48.4	93%	0.925	25%	0.252	S	S	*	.	G	3₁₀ helix	trans	-75	-8.2	-172.2	-64.6	-172	159.6	0	0	115.1
153	G	77	Confident	84	Confident	44 Å²	44	47.9 Å²	47.9	45%	0.454	25%	0.247	S	C	.	.	G	3₁₀ helix	trans	-96.6	25.8	-175	0	0	0	0	0	115.6	G151 E155	G151-G153 VanDerWaalsContact C-N 3.28Å; G151-G153 PolarHBondContact O-N 2.7Å; G153-E155 PolarHBondContact O-N 3.22Å
154	M	87.5	Confident	82.7	Confident	8 Å²	8	51.2 Å²	51.2	4%	0.039	27%	0.271	C	S	.	.			trans	-67.9	117	-173.6	-76.9	179.8	-90.3	0	0	112.8	I30 L62 A146 E147 F150 G151	I30-M154 HydrophobicContact CG2-CB 4.1Å; I30-M154 HydrophobicContact CG2-CG 3.9Å; I30-M154 HydrophobicContact CG2-SD 4.31Å; L62-M154 HydrophobicContact CB-CB 3.91Å; L62-M154 HydrophobicContact CD2-CB 4.32Å; L62-M154 HydrophobicContact CD2-CE 4.43Å; L62-M154 HydrophobicContact CD2-SD 4.01Å; L62-M154 PolarHBondContact N-O 3.24Å; A146-M154 HydrophobicContact CB-SD 4.26Å; E147-M154 HydrophobicContact CB-CE 4.18Å; E147-M154 HydrophobicContact CG-CE 4.34Å; F150-M154 HydrophobicContact CB-CG 3.38Å; F150-M154 HydrophobicContact CB-SD 4.08Å; F150-M154 HydrophobicContact CG-CG 4.26Å; G151-M154 WeakPolarHBondContact O-CE 3.49Å; G151-M154 WeakPolarHBondContact O-CG 3.29Å
155	E	90.9	Very high	81.4	Confident	77 Å²	77	52.2 Å²	52.2	36%	0.36	27%	0.273	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-95	126.5	166.2	-63.9	-170.4	164	0	0	109.7	I30 S31 T59 Y60 G153	I30-E155 WeakPolarHBondContact CA-O 3.44Å; S31-E155 PolarHBondContact N-O 3.28Å; S31-E155 PolarHBondContact O-N 3.4Å; S31-E155 VanDerWaalsContact O-N 3.15Å; T59-E155 HydrophobicContact CG2-CB 3.97Å; Y60-E155 WeakPolarHBondContact O-CA 3.49Å; G153-E155 PolarHBondContact O-N 3.22Å
156	V	91.6	Very high	80.4	Confident	0 Å²	0	54.1 Å²	54.1	0%	0	28%	0.28	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.3	143.2	-175.6	-58.1	0	0	0	0	112.3	L28 H29 I30 Y60 L62 A85 L158	L28-V156 HydrophobicContact CD1-CB 3.79Å; L28-V156 HydrophobicContact CD1-CG1 4.09Å; L28-V156 HydrophobicContact CD1-CG2 4.4Å; H29-V156 CarbonylContact O-C 3.56Å; H29-V156 VanDerWaalsContact O-CA 3.28Å; H29-V156 WeakPolarHBondContact O-CA 3.32Å; I30-V156 HydrophobicContact CD1-CG1 4.36Å; I30-V156 HydrophobicContact CG1-CG1 3.98Å; I30-V156 HydrophobicContact CG2-CG1 4.37Å; Y60-V156 PolarHBondContact N-O 2.89Å; Y60-V156 WeakPolarHBondContact O-CG2 3.19Å; Y60-V156 PolarHBondContact O-N 2.9Å; L62-V156 HydrophobicContact CB-CG1 3.9Å; L62-V156 HydrophobicContact CB-CG2 4.4Å; L62-V156 HydrophobicContact CD1-CG1 4.07Å; L62-V156 HydrophobicContact CD1-CG2 3.97Å; L62-V156 HydrophobicContact CD2-CG1 3.96Å; L62-V156 HydrophobicContact CG-CG1 4.21Å; A85-V156 HydrophobicContact CB-CG2 3.82Å; V156-L158 HydrophobicContact CG2-CD1 4.48Å
157	K	91.7	Very high	79.6	Confident	50 Å²	50	54.5 Å²	54.5	22%	0.217	28%	0.282	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.1	137.6	167.6	-66.9	177	174	-175.5	0	108.6	H29 L54 A57 T59	H29-K157 HydrophobicContact CB-CB 4.28Å; H29-K157 PolarHBondContact N-O 3.33Å; H29-K157 PolarHBondContact O-N 3.36Å; L54-K157 HydrophobicContact CD1-CB 4.11Å; L54-K157 HydrophobicContact CD1-CD 3.75Å; A57-K157 HydrophobicContact CB-CB 4.04Å; A57-K157 HydrophobicContact CB-CD 4.48Å; A57-K157 HydrophobicContact CB-CG 4.5Å; T59-K157 HydrophobicContact CG2-CG 4.45Å; T59-K157 WeakPolarHBondContact OG1-CE 3.28Å
158	L	89.6	Confident	79.3	Confident	8 Å²	8	56.4 Å²	56.4	4%	0.042	29%	0.294	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-111.2	127	175.3	-59.9	90.8	0	0	0	108.3	L28 L41 L50 Y60 A109 L111 V156	L28-L158 HydrophobicContact CD1-CG 4.12Å; L41-L158 HydrophobicContact CD1-CD2 3.78Å; L41-L158 HydrophobicContact CD1-CG 4.2Å; L50-L158 HydrophobicContact CD2-CB 3.55Å; L50-L158 HydrophobicContact CD2-CD2 4.38Å; Y60-L158 HydrophobicContact CD2-CD1 4.09Å; Y60-L158 HydrophobicContact CE2-CD1 4.41Å; A109-L158 HydrophobicContact CB-CD1 4.22Å; L111-L158 HydrophobicContact CD2-CD2 3.84Å; L111-L158 HydrophobicContact CG-CD2 4.37Å; V156-L158 HydrophobicContact CG2-CD1 4.48Å
159	Y	87.8	Confident	79	Confident	21 Å²	21	47 Å²	47	8%	0.082	26%	0.258	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-145.3	151.1	175.7	72.7	-81.3	0	0	0	110.5	A26 V27 H29 E51 L54 P161 T413	A26-Y159 WeakPolarHBondContact CB-O 3.35Å; V27-Y159 HydrophobicContact CB-CD1 4.34Å; V27-Y159 HydrophobicContact CB-CE1 3.74Å; V27-Y159 HydrophobicContact CB-CE2 4.41Å; V27-Y159 HydrophobicContact CG1-CE1 3.65Å; V27-Y159 PolarHBondContact N-O 2.9Å; V27-Y159 PolarHBondContact O-N 2.96Å; H29-Y159 HydrophobicContact CB-CE1 4.18Å; E51-Y159 CarbonylContact O-C 3.45Å; E51-Y159 WeakPolarHBondContact O-CA 3.49Å; E51-Y159 VanDerWaalsContact O-CB 3.26Å; E51-Y159 WeakPolarHBondContact O-CB 3.24Å; L54-Y159 HydrophobicContact CB-CE1 4.48Å; L54-Y159 HydrophobicContact CD1-CD1 3.93Å; L54-Y159 HydrophobicContact CD1-CE1 3.9Å; Y159-P161 HydrophobicContact CD2-CG 4.41Å; Y159-P161 HydrophobicContact CE2-CB 4.49Å; Y159-P161 HydrophobicContact CE2-CG 4.15Å; Y159-T413 HydrophobicContact CE2-CG2 4.34Å
160	A	83.5	Confident	78.9	Confident	13 Å²	13	45.6 Å²	45.6	11%	0.107	25%	0.248	C	C	.	.			trans	-125.7	94.8	179.7	0	0	0	0	0	108.8	A26 F43 L50 E51 E52	A26-A160 HydrophobicContact CB-CB 4.07Å; F43-A160 HydrophobicContact CD1-CB 4.47Å; F43-A160 HydrophobicContact CE1-CB 3.59Å; F43-A160 HydrophobicContact CE2-CB 4.33Å; F43-A160 HydrophobicContact CZ-CB 3.5Å; L50-A160 HydrophobicContact CB-CB 3.8Å; L50-A160 HydrophobicContact CD1-CB 4.26Å; E51-A160 PolarHBondContact O-N 3.48Å; E52-A160 WeakPolarHBondContact CA-O 2.89Å
161	P	74.3	Confident	79	Confident	30 Å²	30	48.7 Å²	48.7	20%	0.195	27%	0.268	C	S	.	.	P	Polyproline II helix	trans	-66.4	140.6	-178.2	27.1	-31.4	0	0	0	111	E52 Y159 Y163 T413	E52-P161 WeakPolarHBondContact O-CA 3.33Å; Y159-P161 HydrophobicContact CD2-CG 4.41Å; Y159-P161 HydrophobicContact CE2-CB 4.49Å; Y159-P161 HydrophobicContact CE2-CG 4.15Å; P161-Y163 HydrophobicContact CG-CE1 4.37Å; P161-Y163 WeakPolarHBondContact O-CD2 3.32Å; P161-Y163 WeakPolarHBondContact O-CE2 3.26Å; P161-T413 HydrophobicContact CG-CG2 3.59Å
162	Q	66.3	Low	79.3	Confident	91 Å²	91	49.2 Å²	49.2	43%	0.425	27%	0.265	S	S	.	.	P	Polyproline II helix	trans	-74.3	134.9	171.6	-68.3	-164.8	-8.8	0	0	110.5	E52	E52-Q162 HydrophobicContact CG-CG 4.05Å; E52-Q162 VanDerWaalsContact OE1-CD 3.28Å; E52-Q162 PolarHBondContact OE1-NE2 2.94Å
163	Y	63.8	Low	79.9	Confident	24 Å²	24	39.8 Å²	39.8	9%	0.094	22%	0.22	C	C	.	.	B	Isolated β-bridge	trans	-103.8	138.3	178.9	-53	-88.5	0	0	0	111	C23 P161 A411 T413 Q414	C23-Y163 HydrophobicContact CB-CD2 3.61Å; C23-Y163 HydrophobicContact CB-CE2 3.57Å; C23-Y163 VanDerWaalsContact SG-CD2 3.54Å; P161-Y163 HydrophobicContact CG-CE1 4.37Å; P161-Y163 WeakPolarHBondContact O-CD2 3.32Å; P161-Y163 WeakPolarHBondContact O-CE2 3.26Å; Y163-A411 HydrophobicContact CD1-CB 4.01Å; Y163-A411 HydrophobicContact CE1-CB 3.86Å; Y163-T413 VanDerWaalsContact CE1-OG1 3.25Å; Y163-T413 WeakPolarHBondContact CE1-OG1 3.4Å; Y163-T413 VanDerWaalsContact CZ-OG1 3.29Å; Y163-T413 WeakPolarHBondContact OH-CB 3.39Å; Y163-T413 PolarHBondContact OH-OG1 3.39Å; Y163-Q414 HydrophobicContact CE1-CG 4.36Å
164	S	61.3	Low	80.6	Confident	72 Å²	72	39.1 Å²	39.1	50%	0.503	21%	0.206	S	C	.	.	P	Polyproline II helix	trans	-77.2	139.5	164.3	50	0	0	0	0	109.8	I166	S164-I166 PolarHBondContact O-N 3.48Å; S164-I166 VanDerWaalsContact O-N 3.16Å; S164-I166 PolarHBondContact OG-O 3.33Å; S164-I166 VanDerWaalsContact OG-O 3.14Å
165	K	61.6	Low	80.8	Confident	63 Å²	63	44 Å²	44	27%	0.274	23%	0.232	S	C	.	.	S	Bend	trans	-61.1	-20.9	172.3	-76.4	-176.9	175.3	-177.9	0	113.5	I18 S19 V21 L473	I18-K165 HydrophobicContact CG2-CD 3.88Å; S19-K165 WeakPolarHBondContact O-CD 3.36Å; S19-K165 WeakPolarHBondContact O-CE 3.47Å; S19-K165 WeakPolarHBondContact O-CG 3.43Å; V21-K165 HydrophobicContact CG2-CD 3.98Å; V21-K165 HydrophobicContact CG2-CG 3.68Å; K165-L473 WeakPolarHBondContact O-CD2 3.48Å
166	I	65.7	Low	81	Confident	73 Å²	73	42.1 Å²	42.1	37%	0.374	22%	0.224	S	C	.	.			trans	-101.8	108.6	-179.7	-58.4	157.2	0	0	0	108.1	I15 S164 L473	I15-I166 HydrophobicContact CG2-CD1 3.21Å; I15-I166 HydrophobicContact CG2-CG1 4.24Å; I15-I166 WeakPolarHBondContact O-CD1 3.34Å; S164-I166 PolarHBondContact O-N 3.48Å; S164-I166 VanDerWaalsContact O-N 3.16Å; S164-I166 PolarHBondContact OG-O 3.33Å; S164-I166 VanDerWaalsContact OG-O 3.14Å; I166-L473 HydrophobicContact CG1-CD1 4.36Å
167	D	71.7	Confident	81.1	Confident	9 Å²	9	42.1 Å²	42.1	5%	0.048	22%	0.224	C	C	.	.			trans	-98.9	148.5	174.9	-73.2	-29.3	0	0	0	110.6	N169 I170 R408 S410	D167-N169 WeakPolarHBondContact CB-OD1 3.32Å; D167-N169 PolarHBondContact O-N 3.39Å; D167-N169 VanDerWaalsContact O-N 3.08Å; D167-I170 PolarHBondContact O-N 2.99Å; D167-R408 VanDerWaalsContact OD2-CD 3.25Å; D167-R408 WeakPolarHBondContact OD2-CD 3.19Å; D167-R408 WeakPolarHBondContact OD2-CG 3.17Å; D167-R408 IonicContact OD2-NE 3.65Å; D167-R408 PolarHBondContact OD2-NE 2.83Å; D167-S410 WeakPolarHBondContact CB-OG 3.23Å; D167-S410 WeakPolarHBondContact OD1-CB 3.49Å; D167-S410 PolarHBondContact OD1-OG 3.47Å
168	L	81.4	Confident	81.3	Confident	108 Å²	108	41.3 Å²	41.3	57%	0.565	22%	0.222	S	C	*	.	H	α-helix	trans	-59.7	-21.8	176.6	-173.4	136.3	0	0	0	112.4	I170 V171 V172 F409	L168-I170 VanDerWaalsContact C-N 3.34Å; L168-I170 PolarHBondContact O-N 3.11Å; L168-V171 PolarHBondContact O-N 2.92Å; L168-V172 HydrophobicContact CD2-CG2 3.72Å; L168-V172 WeakPolarHBondContact O-CG2 3.41Å; L168-V172 PolarHBondContact O-N 3.48Å; L168-F409 HydrophobicContact CD2-CD2 3.65Å; L168-F409 HydrophobicContact CD2-CE2 4.17Å; L168-F409 HydrophobicContact CD2-CG 4.34Å
169	N	82.1	Confident	81.6	Confident	0 Å²	0	43.2 Å²	43.2	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-66.4	-32.3	179	75.7	-20	0	0	0	113.4	D167 V171 V172 L173 V406 P407 R408 F409 S422	D167-N169 WeakPolarHBondContact CB-OD1 3.32Å; D167-N169 PolarHBondContact O-N 3.39Å; D167-N169 VanDerWaalsContact O-N 3.08Å; N169-V171 VanDerWaalsContact C-N 3.31Å; N169-V172 PolarHBondContact O-N 3.41Å; N169-L173 VanDerWaalsContact O-CB 3.29Å; N169-L173 WeakPolarHBondContact O-CB 3.09Å; N169-L173 PolarHBondContact O-N 2.97Å; N169-V406 HydrophobicContact CB-CB 4.4Å; N169-V406 HydrophobicContact CB-CG1 3.78Å; N169-V406 PolarHBondContact ND2-O 2.88Å; N169-P407 WeakPolarHBondContact CB-O 3.27Å; N169-R408 WeakPolarHBondContact ND2-CA 3.22Å; N169-R408 WeakPolarHBondContact ND2-CG 3.18Å; N169-F409 HydrophobicContact CB-CD2 3.91Å; N169-F409 HydrophobicContact CB-CE2 4.15Å; N169-S422 WeakPolarHBondContact ND2-CB 3.16Å; N169-S422 PolarHBondContact ND2-OG 3.49Å
170	I	84.8	Confident	81.9	Confident	26 Å²	26	42.3 Å²	42.3	13%	0.133	24%	0.235	C	C	.	.	H	α-helix	trans	-65.1	-42.2	176.5	-61.1	174.5	0	0	0	108.9	D167 L168 L173 L174 F469 L473	D167-I170 PolarHBondContact O-N 2.99Å; L168-I170 VanDerWaalsContact C-N 3.34Å; L168-I170 PolarHBondContact O-N 3.11Å; I170-L173 PolarHBondContact O-N 2.94Å; I170-L174 VanDerWaalsContact O-CB 3.31Å; I170-L174 WeakPolarHBondContact O-CB 3.25Å; I170-L174 PolarHBondContact O-N 3.5Å; I170-F469 HydrophobicContact CG2-CB 4.16Å; I170-F469 HydrophobicContact CG2-CD1 3.96Å; I170-F469 HydrophobicContact CG2-CD2 3.94Å; I170-F469 HydrophobicContact CG2-CE1 4.35Å; I170-F469 HydrophobicContact CG2-CE2 4.33Å; I170-F469 HydrophobicContact CG2-CG 3.76Å; I170-L473 HydrophobicContact CD1-CD1 4.24Å; I170-L473 HydrophobicContact CD1-CD2 4.18Å
171	V	86.7	Confident	82.5	Confident	75 Å²	75	41.7 Å²	41.7	46%	0.455	23%	0.23	S	C	.	.	H	α-helix	trans	-64	-44.9	176.5	-177.8	0	0	0	0	110.7	L168 N169 L173 L174 L175	L168-V171 PolarHBondContact O-N 2.92Å; N169-V171 VanDerWaalsContact C-N 3.31Å; V171-L173 VanDerWaalsContact C-N 3.34Å; V171-L173 PolarHBondContact O-N 3.04Å; V171-L174 WeakPolarHBondContact O-CB 3.28Å; V171-L174 PolarHBondContact O-N 3.32Å; V171-L175 HydrophobicContact CG1-CD1 4.3Å; V171-L175 VanDerWaalsContact O-CG 3.3Å; V171-L175 WeakPolarHBondContact O-CG 3.18Å; V171-L175 PolarHBondContact O-N 3.5Å
172	V	89.6	Confident	83.6	Confident	43 Å²	43	41.3 Å²	41.3	26%	0.261	23%	0.23	S	C	.	.	H	α-helix	trans	-60.8	-44.2	176.2	171.5	0	0	0	0	111.2	L168 N169 L175 I176 V406 F409	L168-V172 HydrophobicContact CD2-CG2 3.72Å; L168-V172 WeakPolarHBondContact O-CG2 3.41Å; L168-V172 PolarHBondContact O-N 3.48Å; N169-V172 PolarHBondContact O-N 3.41Å; V172-L175 PolarHBondContact O-N 2.75Å; V172-I176 HydrophobicContact CG1-CD1 3.84Å; V172-I176 HydrophobicContact CG1-CG1 4.47Å; V172-I176 VanDerWaalsContact O-CG1 3.31Å; V172-I176 WeakPolarHBondContact O-CG1 3.25Å; V172-I176 PolarHBondContact O-N 3.13Å; V172-V406 HydrophobicContact CB-CG1 4.32Å; V172-V406 HydrophobicContact CG1-CG1 4.03Å; V172-V406 HydrophobicContact CG1-CG2 4.45Å; V172-F409 HydrophobicContact CB-CE2 4.39Å; V172-F409 HydrophobicContact CG2-CE2 4.05Å
173	L	89.4	Confident	84.9	Confident	0 Å²	0	41.6 Å²	41.6	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-63.7	-42.6	178.5	-171.2	61.6	0	0	0	111.8	N169 I170 V171 I176 A177 M404 V406 L424 F469	N169-L173 VanDerWaalsContact O-CB 3.29Å; N169-L173 WeakPolarHBondContact O-CB 3.09Å; N169-L173 PolarHBondContact O-N 2.97Å; I170-L173 PolarHBondContact O-N 2.94Å; V171-L173 VanDerWaalsContact C-N 3.34Å; V171-L173 PolarHBondContact O-N 3.04Å; L173-I176 PolarHBondContact O-N 3.29Å; L173-A177 WeakPolarHBondContact O-CB 3.4Å; L173-A177 PolarHBondContact O-N 3.19Å; L173-M404 HydrophobicContact CD1-CB 4Å; L173-V406 HydrophobicContact CB-CG2 4.33Å; L173-V406 HydrophobicContact CD1-CG2 3.91Å; L173-L424 HydrophobicContact CD1-CB 3.86Å; L173-L424 HydrophobicContact CD1-CD2 4.28Å; L173-L424 HydrophobicContact CD2-CB 3.94Å; L173-L424 HydrophobicContact CG-CB 4.05Å; L173-L424 HydrophobicContact CG-CD2 4.19Å; L173-F469 HydrophobicContact CD2-CE1 4.28Å; L173-F469 HydrophobicContact CD2-CZ 3.81Å; L173-F469 HydrophobicContact CG-CZ 4.34Å
174	L	91.3	Very high	86.3	Confident	30 Å²	30	40.4 Å²	40.4	16%	0.157	23%	0.229	C	C	.	.	H	α-helix	trans	-59.1	-45.9	173.9	-178.3	65.2	0	0	0	111.4	I170 V171 A177 I178 L462 L465 V466	I170-L174 VanDerWaalsContact O-CB 3.31Å; I170-L174 WeakPolarHBondContact O-CB 3.25Å; I170-L174 PolarHBondContact O-N 3.5Å; V171-L174 WeakPolarHBondContact O-CB 3.28Å; V171-L174 PolarHBondContact O-N 3.32Å; L174-A177 PolarHBondContact O-N 2.93Å; L174-I178 HydrophobicContact CD1-CD1 3.8Å; L174-I178 HydrophobicContact CD1-CG1 4.4Å; L174-I178 HydrophobicContact CG-CD1 3.76Å; L174-I178 WeakPolarHBondContact O-CD1 3.42Å; L174-I178 VanDerWaalsContact O-CG1 3.24Å; L174-I178 WeakPolarHBondContact O-CG1 3.25Å; L174-I178 PolarHBondContact O-N 3.32Å; L174-L462 HydrophobicContact CD1-CD1 4.08Å; L174-L462 HydrophobicContact CD2-CD1 4.16Å; L174-L462 HydrophobicContact CG-CD1 4.35Å; L174-L465 HydrophobicContact CD1-CB 4.02Å; L174-L465 HydrophobicContact CD1-CD2 3.54Å; L174-L465 HydrophobicContact CD1-CG 3.73Å; L174-V466 HydrophobicContact CD1-CG2 4.17Å; L174-V466 HydrophobicContact CD2-CG2 3.84Å
175	L	92.7	Very high	87.8	Confident	111 Å²	111	37 Å²	37	58%	0.581	21%	0.205	S	C	*	.	H	α-helix	trans	-63.3	-44.8	177.8	-71.6	174.3	0	0	0	111.9	V171 V172 A179	V171-L175 HydrophobicContact CG1-CD1 4.3Å; V171-L175 VanDerWaalsContact O-CG 3.3Å; V171-L175 WeakPolarHBondContact O-CG 3.18Å; V171-L175 PolarHBondContact O-N 3.5Å; V172-L175 PolarHBondContact O-N 2.75Å; L175-A179 WeakPolarHBondContact O-CB 3.47Å; L175-A179 PolarHBondContact O-N 2.91Å
176	I	93.4	Very high	89.3	Confident	37 Å²	37	37.8 Å²	37.8	19%	0.19	21%	0.212	C	C	.	.	H	α-helix	trans	-61.3	-46	177.2	-68.4	167.5	0	0	0	110.5	V172 L173 A179 T180 I321 M404 V406	V172-I176 HydrophobicContact CG1-CD1 3.84Å; V172-I176 HydrophobicContact CG1-CG1 4.47Å; V172-I176 VanDerWaalsContact O-CG1 3.31Å; V172-I176 WeakPolarHBondContact O-CG1 3.25Å; V172-I176 PolarHBondContact O-N 3.13Å; L173-I176 PolarHBondContact O-N 3.29Å; I176-A179 PolarHBondContact O-N 3.44Å; I176-T180 VanDerWaalsContact O-CB 3.31Å; I176-T180 WeakPolarHBondContact O-CB 3.4Å; I176-T180 PolarHBondContact O-N 2.8Å; I176-T180 PolarHBondContact O-OG1 3.19Å; I176-I321 HydrophobicContact CG2-CD1 3.96Å; I176-I321 HydrophobicContact CG2-CG1 4.18Å; I176-M404 HydrophobicContact CG2-CE 4.07Å; I176-M404 HydrophobicContact CG2-SD 3.58Å; I176-M404 VanDerWaalsContact CG2-SD 3.58Å; I176-V406 HydrophobicContact CD1-CG2 4.28Å
177	A	94.4	Very high	90.5	Very high	0 Å²	0	36.7 Å²	36.7	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-61.5	-49.9	-179.5	0	0	0	0	0	111.7	L173 L174 T180 V181 L424 I429 Y461 L465	L173-A177 WeakPolarHBondContact O-CB 3.4Å; L173-A177 PolarHBondContact O-N 3.19Å; L174-A177 PolarHBondContact O-N 2.93Å; A177-T180 PolarHBondContact O-N 3.06Å; A177-V181 WeakPolarHBondContact O-CG2 3.18Å; A177-V181 PolarHBondContact O-N 3.13Å; A177-L424 HydrophobicContact CB-CD2 3.77Å; A177-I429 HydrophobicContact CB-CD1 4.37Å; A177-I429 HydrophobicContact CB-CG1 4.37Å; A177-Y461 HydrophobicContact CB-CE1 4.35Å; A177-L465 HydrophobicContact CB-CD2 3.6Å
178	I	95.4	Very high	91.4	Very high	34 Å²	34	36.4 Å²	36.4	17%	0.174	20%	0.201	C	C	.	.	H	α-helix	trans	-64.5	-44.3	179.8	-64.7	161.5	0	0	0	111.1	L174 T180 V181 A182 V458 Y461 L462	L174-I178 HydrophobicContact CD1-CD1 3.8Å; L174-I178 HydrophobicContact CD1-CG1 4.4Å; L174-I178 HydrophobicContact CG-CD1 3.76Å; L174-I178 WeakPolarHBondContact O-CD1 3.42Å; L174-I178 VanDerWaalsContact O-CG1 3.24Å; L174-I178 WeakPolarHBondContact O-CG1 3.25Å; L174-I178 PolarHBondContact O-N 3.32Å; I178-T180 VanDerWaalsContact C-N 3.31Å; I178-T180 PolarHBondContact O-N 2.84Å; I178-V181 PolarHBondContact O-N 3.36Å; I178-A182 VanDerWaalsContact O-CB 3.23Å; I178-A182 WeakPolarHBondContact O-CB 3.48Å; I178-A182 PolarHBondContact O-N 2.88Å; I178-V458 HydrophobicContact CG2-CG1 4.46Å; I178-Y461 HydrophobicContact CG1-CD1 4.41Å; I178-Y461 HydrophobicContact CG1-CE1 4.41Å; I178-L462 HydrophobicContact CD1-CB 4.04Å; I178-L462 HydrophobicContact CD1-CD1 3.34Å; I178-L462 HydrophobicContact CD1-CG 4.12Å; I178-L462 HydrophobicContact CG1-CB 4.37Å; I178-L462 HydrophobicContact CG1-CD1 4.44Å
179	A	95.8	Very high	91.8	Very high	47 Å²	47	32.4 Å²	32.4	39%	0.388	18%	0.179	S	C	.	.	H	α-helix	trans	-59.9	-44.2	177	0	0	0	0	0	110.8	L175 I176 A182 L183	L175-A179 WeakPolarHBondContact O-CB 3.47Å; L175-A179 PolarHBondContact O-N 2.91Å; I176-A179 PolarHBondContact O-N 3.44Å; A179-A182 PolarHBondContact O-N 3.2Å; A179-L183 WeakPolarHBondContact O-CB 3.49Å; A179-L183 WeakPolarHBondContact O-CG 3.4Å; A179-L183 PolarHBondContact O-N 2.86Å
180	T	95.7	Very high	92.1	Very high	3 Å²	3	34.6 Å²	34.6	2%	0.018	20%	0.197	C	C	.	.	H	α-helix	trans	-62.9	-47.8	178.9	-55.9	0	0	0	0	111.6	I176 A177 I178 G184 I321 C324 L325 M328 I429	I176-T180 VanDerWaalsContact O-CB 3.31Å; I176-T180 WeakPolarHBondContact O-CB 3.4Å; I176-T180 PolarHBondContact O-N 2.8Å; I176-T180 PolarHBondContact O-OG1 3.19Å; A177-T180 PolarHBondContact O-N 3.06Å; I178-T180 VanDerWaalsContact C-N 3.31Å; I178-T180 PolarHBondContact O-N 2.84Å; T180-G184 PolarHBondContact O-N 3.31Å; T180-I321 HydrophobicContact CG2-CG2 4.4Å; T180-C324 HydrophobicContact CG2-CB 3.68Å; T180-L325 HydrophobicContact CG2-CD2 4.29Å; T180-L325 HydrophobicContact CG2-CG 4.43Å; T180-L325 WeakPolarHBondContact O-CD2 3.43Å; T180-M328 HydrophobicContact CG2-CE 4.17Å; T180-M328 WeakPolarHBondContact O-CE 3.38Å; T180-I429 HydrophobicContact CG2-CG2 3.94Å
181	V	96	Very high	92.1	Very high	0 Å²	0	34.5 Å²	34.5	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-64.1	-44.7	178.4	170.7	0	0	0	0	111.6	A177 I178 G184 G185 I429 V436 Y461	A177-V181 WeakPolarHBondContact O-CG2 3.18Å; A177-V181 PolarHBondContact O-N 3.13Å; I178-V181 PolarHBondContact O-N 3.36Å; V181-G184 PolarHBondContact O-N 2.97Å; V181-G185 PolarHBondContact O-N 3.46Å; V181-I429 HydrophobicContact CG2-CG2 3.77Å; V181-V436 HydrophobicContact CG1-CB 3.9Å; V181-V436 HydrophobicContact CG1-CG1 3.9Å; V181-V436 HydrophobicContact CG1-CG2 3.69Å; V181-Y461 HydrophobicContact CB-CD1 4.41Å; V181-Y461 HydrophobicContact CB-CE1 4.31Å; V181-Y461 HydrophobicContact CG1-CD1 4.43Å; V181-Y461 HydrophobicContact CG2-CD1 4.22Å; V181-Y461 HydrophobicContact CG2-CE1 3.74Å; V181-Y461 HydrophobicContact CG2-CE2 4.18Å
182	A	95.8	Very high	92	Very high	22 Å²	22	31.9 Å²	31.9	18%	0.182	18%	0.181	C	C	.	.	H	α-helix	trans	-64.8	-47	179.2	0	0	0	0	0	111.7	I178 A179 G185 L186 F454	I178-A182 VanDerWaalsContact O-CB 3.23Å; I178-A182 WeakPolarHBondContact O-CB 3.48Å; I178-A182 PolarHBondContact O-N 2.88Å; A179-A182 PolarHBondContact O-N 3.2Å; A182-G185 PolarHBondContact O-N 3.27Å; A182-L186 WeakPolarHBondContact O-CB 3.43Å; A182-L186 VanDerWaalsContact O-CG 3.27Å; A182-L186 WeakPolarHBondContact O-CG 3.24Å; A182-L186 PolarHBondContact O-N 2.83Å; A182-F454 HydrophobicContact CB-CZ 4.41Å
183	L	95.1	Very high	91.8	Very high	96 Å²	96	35.8 Å²	35.8	50%	0.503	19%	0.191	S	C	.	.	H	α-helix	trans	-63.1	-42	176.4	-72	172.3	0	0	0	111.5	A179 G185 L186 W187 L325	A179-L183 WeakPolarHBondContact O-CB 3.49Å; A179-L183 WeakPolarHBondContact O-CG 3.4Å; A179-L183 PolarHBondContact O-N 2.86Å; L183-G185 PolarHBondContact O-N 3.46Å; L183-L186 PolarHBondContact O-N 3.36Å; L183-W187 VanDerWaalsContact O-CB 3.27Å; L183-W187 WeakPolarHBondContact O-CB 3.37Å; L183-W187 PolarHBondContact O-N 3.32Å; L183-L325 HydrophobicContact CB-CD2 3.78Å
184	G	93.6	Very high	91.6	Very high	0 Å²	0	42.2 Å²	42.2	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-61.4	-44	176.8	0	0	0	0	0	112.4	T180 V181 W187 S188	T180-G184 PolarHBondContact O-N 3.31Å; V181-G184 PolarHBondContact O-N 2.97Å; G184-W187 PolarHBondContact O-N 3.49Å; G184-S188 WeakPolarHBondContact O-CB 3.39Å; G184-S188 PolarHBondContact O-N 2Å
185	G	92.8	Very high	91	Very high	0 Å²	0	45.4 Å²	45.4	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-63.1	-46	173.4	0	0	0	0	0	112.7	V181 A182 L183 W187 S188 R189 S440	V181-G185 PolarHBondContact O-N 3.46Å; A182-G185 PolarHBondContact O-N 3.27Å; L183-G185 PolarHBondContact O-N 3.46Å; G185-W187 VanDerWaalsContact C-N 3.34Å; G185-W187 PolarHBondContact O-N 2.93Å; G185-S188 WeakPolarHBondContact O-CB 3.41Å; G185-S188 PolarHBondContact O-N 2.84Å; G185-R189 VanDerWaalsContact O-CB 3.24Å; G185-R189 WeakPolarHBondContact O-CB 3.25Å; G185-R189 PolarHBondContact O-N 3.28Å; G185-S440 PolarHBondContact O-OG 3.43Å
186	L	92.4	Very high	90.5	Very high	80 Å²	80	43.7 Å²	43.7	42%	0.419	22%	0.222	S	C	.	.	H	α-helix	trans	-64.6	-36.7	177.8	-70.6	174.8	0	0	0	112.8	A182 L183 R189 A190 F454	A182-L186 WeakPolarHBondContact O-CB 3.43Å; A182-L186 VanDerWaalsContact O-CG 3.27Å; A182-L186 WeakPolarHBondContact O-CG 3.24Å; A182-L186 PolarHBondContact O-N 2.83Å; L183-L186 PolarHBondContact O-N 3.36Å; L186-R189 WeakPolarHBondContact O-CB 3.21Å; L186-R189 PolarHBondContact O-N 2.92Å; L186-A190 PolarHBondContact O-N 3.29Å; L186-F454 HydrophobicContact CD2-CE1 3.8Å; L186-F454 HydrophobicContact CD2-CZ 3.88Å; L186-F454 HydrophobicContact CG-CE1 4.14Å; L186-F454 HydrophobicContact CG-CZ 3.76Å
187	W	91.3	Very high	90.1	Very high	50 Å²	50	48.3 Å²	48.3	19%	0.189	24%	0.241	C	C	.	.	H	α-helix	trans	-72.3	-44.8	178.9	-166.7	0.4	0	0	0	111.6	L183 G184 G185 R189 A190 C191 S261 C262 A265 L325 K329	L183-W187 VanDerWaalsContact O-CB 3.27Å; L183-W187 WeakPolarHBondContact O-CB 3.37Å; L183-W187 PolarHBondContact O-N 3.32Å; G184-W187 PolarHBondContact O-N 3.49Å; G185-W187 VanDerWaalsContact C-N 3.34Å; G185-W187 PolarHBondContact O-N 2.93Å; W187-R189 PolarHBondContact O-N 2.92Å; W187-A190 PolarHBondContact O-N 2.8Å; W187-A190 VanDerWaalsContact O-N 3.16Å; W187-C191 PolarHBondContact O-N 2.9Å; W187-C191 VanDerWaalsContact O-N 3.08Å; W187-S261 WeakPolarHBondContact CZ2-O 3.41Å; W187-C262 VanDerWaalsContact CH2-CA 3.43Å; W187-C262 HydrophobicContact CH2-CB 3.91Å; W187-C262 HydrophobicContact CZ3-CB 4.2Å; W187-A265 HydrophobicContact CH2-CB 4.43Å; W187-A265 HydrophobicContact CZ2-CB 3.61Å; W187-L325 HydrophobicContact CE3-CB 3.96Å; W187-L325 HydrophobicContact CE3-CD1 4.35Å; W187-L325 HydrophobicContact CZ3-CB 3.76Å; W187-L325 HydrophobicContact CZ3-CD1 4.15Å; W187-K329 HydrophobicContact CZ2-CD 4.13Å
188	S	89.8	Confident	89.4	Confident	2 Å²	2	51 Å²	51	1%	0.014	26%	0.259	C	S	.	.	H	α-helix	trans	-52	-42	169	166.9	0	0	0	0	111.7	G184 G185 E192 R441	G184-S188 WeakPolarHBondContact O-CB 3.39Å; G184-S188 PolarHBondContact O-N 2Å; G185-S188 WeakPolarHBondContact O-CB 3.41Å; G185-S188 PolarHBondContact O-N 2.84Å; S188-E192 PolarHBondContact O-N 2.84Å; S188-R441 PolarHBondContact OG-NE 2.6Å; S188-R441 PolarHBondContact OG-NH2 2.89Å
189	R	89.5	Confident	88.4	Confident	25 Å²	25	55.8 Å²	55.8	9%	0.094	28%	0.279	C	S	.	.	H	α-helix	trans	-67.1	-42.6	176.8	-173.8	177.9	-158.8	-155	0.9	113.9	G185 L186 W187 C191 E192 R193 S440 I444 N451	G185-R189 VanDerWaalsContact O-CB 3.24Å; G185-R189 WeakPolarHBondContact O-CB 3.25Å; G185-R189 PolarHBondContact O-N 3.28Å; L186-R189 WeakPolarHBondContact O-CB 3.21Å; L186-R189 PolarHBondContact O-N 2.92Å; W187-R189 PolarHBondContact O-N 2.92Å; R189-C191 VanDerWaalsContact C-N 3.34Å; R189-E192 PolarHBondContact O-N 3.36Å; R189-R193 PolarHBondContact O-N 3.02Å; R189-S440 PolarHBondContact NE-O 3.12Å; R189-I444 HydrophobicContact CB-CD1 4.4Å; R189-I444 HydrophobicContact CG-CD1 3.29Å; R189-I444 HydrophobicContact CG-CG1 3.89Å; R189-I444 VanDerWaalsContact O-CD1 3.3Å; R189-I444 WeakPolarHBondContact O-CD1 3.33Å; R189-N451 PolarHBondContact NH1-ND2 3.46Å; R189-N451 PolarHBondContact NH1-OD1 2.93Å; R189-N451 PolarHBondContact NH2-OD1 3.41Å
190	A	88.2	Confident	87.5	Confident	45 Å²	45	57.8 Å²	57.8	37%	0.372	30%	0.296	S	S	.	.	H	α-helix	trans	-61.7	-44.3	178.3	0	0	0	0	0	111.2	L186 W187 E192 R193 E194	L186-A190 PolarHBondContact O-N 3.29Å; W187-A190 PolarHBondContact O-N 2.8Å; W187-A190 VanDerWaalsContact O-N 3.16Å; A190-E192 PolarHBondContact O-N 3.47Å; A190-R193 WeakPolarHBondContact O-CB 3.32Å; A190-R193 PolarHBondContact O-N 2.85Å; A190-E194 PolarHBondContact O-N 2.99Å; A190-E194 VanDerWaalsContact O-N 3.11Å
191	C	85.1	Confident	86.5	Confident	24 Å²	24	61.8 Å²	61.8	16%	0.162	33%	0.329	C	S	.	.	H	α-helix	trans	-59.4	-45.9	175.8	-172.9	0	0	0	0	112	W187 R189 R193 E194 R195 R214	W187-C191 PolarHBondContact O-N 2.9Å; W187-C191 VanDerWaalsContact O-N 3.08Å; R189-C191 VanDerWaalsContact C-N 3.34Å; C191-R193 VanDerWaalsContact C-N 3.3Å; C191-R193 PolarHBondContact O-N 3.38Å; C191-E194 PolarHBondContact O-N 3.4Å; C191-R195 PolarHBondContact O-N 2.78Å; C191-R195 VanDerWaalsContact O-N 3.12Å; C191-R214 PolarHBondContact SG-NH2 2.87Å
192	E	84.3	Confident	84.7	Confident	20 Å²	20	64.9 Å²	64.9	9%	0.093	36%	0.361	C	S	.	.	H	α-helix	trans	-64.3	-35	177.6	-173.8	63.9	-172	0	0	112.6	S188 R189 A190 R195 L196 R441 I444 W445	S188-E192 PolarHBondContact O-N 2.84Å; R189-E192 PolarHBondContact O-N 3.36Å; A190-E192 PolarHBondContact O-N 3.47Å; E192-R195 WeakPolarHBondContact O-CB 3.17Å; E192-R195 PolarHBondContact O-N 3.04Å; E192-L196 HydrophobicContact CG-CD1 4.44Å; E192-L196 WeakPolarHBondContact O-CG 3.26Å; E192-L196 PolarHBondContact O-N 3.47Å; E192-R441 HydrophobicContact CB-CG 4.15Å; E192-R441 HydrophobicContact CG-CB 4.42Å; E192-R441 HydrophobicContact CG-CG 4.18Å; E192-I444 HydrophobicContact CB-CD1 4.42Å; E192-W445 PolarHBondContact OE1-NE1 3.02Å
193	R	85.8	Confident	82.6	Confident	125 Å²	125	66.6 Å²	66.6	47%	0.472	38%	0.381	S	S	.	.	H	α-helix	trans	-65.9	-42.5	176.3	178.9	-178.8	-68.6	-143.6	-4.3	112.1	R189 A190 C191 R195 L196 K197 I444	R189-R193 PolarHBondContact O-N 3.02Å; A190-R193 WeakPolarHBondContact O-CB 3.32Å; A190-R193 PolarHBondContact O-N 2.85Å; C191-R193 VanDerWaalsContact C-N 3.3Å; C191-R193 PolarHBondContact O-N 3.38Å; R193-R195 VanDerWaalsContact C-N 3.31Å; R193-L196 PolarHBondContact O-N 3.21Å; R193-K197 HydrophobicContact CG-CD 4.5Å; R193-K197 WeakPolarHBondContact O-CG 3.44Å; R193-K197 PolarHBondContact O-N 2.85Å; R193-I444 HydrophobicContact CB-CD1 4.16Å
194	E	84.6	Confident	80	Confident	135 Å²	135	65 Å²	65	63%	0.631	39%	0.388	S	S	*	.	H	α-helix	trans	-62.7	-42.2	176.7	-74.2	173.7	-177.8	0	0	111	A190 C191 K197 S198	A190-E194 PolarHBondContact O-N 2.99Å; A190-E194 VanDerWaalsContact O-N 3.11Å; C191-E194 PolarHBondContact O-N 3.4Å; E194-K197 WeakPolarHBondContact O-CB 3.27Å; E194-K197 PolarHBondContact O-N 3.46Å; E194-S198 PolarHBondContact O-N 3.09Å
195	R	79.9	Confident	77.7	Confident	98 Å²	98	70.3 Å²	70.3	37%	0.37	43%	0.431	S	S	.	.	H	α-helix	trans	-56.4	-53.7	173.7	-176.2	-179.1	171.7	178.1	1.8	111.5	C191 E192 R193 K197 S198 F199	C191-R195 PolarHBondContact O-N 2.78Å; C191-R195 VanDerWaalsContact O-N 3.12Å; E192-R195 WeakPolarHBondContact O-CB 3.17Å; E192-R195 PolarHBondContact O-N 3.04Å; R193-R195 VanDerWaalsContact C-N 3.31Å; R195-K197 VanDerWaalsContact C-N 3.26Å; R195-K197 PolarHBondContact O-N 3.18Å; R195-S198 PolarHBondContact O-N 2.86Å; R195-S198 PolarHBondContact O-OG 3.28Å; R195-F199 HydrophobicContact CG-CD2 3.87Å; R195-F199 HydrophobicContact CG-CE2 3.57Å; R195-F199 VanDerWaalsContact O-CD2 3.23Å; R195-F199 WeakPolarHBondContact O-CD2 3.28Å; R195-F199 PolarHBondContact O-N 3.05Å; R195-F199 VanDerWaalsContact O-N 3.08Å
196	L	81.4	Confident	74.9	Confident	74 Å²	74	79.4 Å²	79.4	39%	0.387	47%	0.474	S	S	.	.	H	α-helix	trans	-59.2	-36.4	179.1	-72.5	165.5	0	0	0	112.9	E192 R193 A200 I444	E192-L196 HydrophobicContact CG-CD1 4.44Å; E192-L196 WeakPolarHBondContact O-CG 3.26Å; E192-L196 PolarHBondContact O-N 3.47Å; R193-L196 PolarHBondContact O-N 3.21Å; L196-A200 WeakPolarHBondContact O-CB 3.34Å; L196-A200 PolarHBondContact O-N 2.91Å; L196-I444 HydrophobicContact CD1-CG2 3.49Å; L196-I444 VanDerWaalsContact CD1-CG2 3.49Å
197	K	84.5	Confident	72.1	Confident	134 Å²	134	84.3 Å²	84.3	58%	0.583	50%	0.495	S	S	*	.	H	α-helix	trans	-66.1	-41.2	174	-73.5	175.4	176.9	-175.9	0	112.3	R193 E194 R195 F199 A200 A201	R193-K197 HydrophobicContact CG-CD 4.5Å; R193-K197 WeakPolarHBondContact O-CG 3.44Å; R193-K197 PolarHBondContact O-N 2.85Å; E194-K197 WeakPolarHBondContact O-CB 3.27Å; E194-K197 PolarHBondContact O-N 3.46Å; R195-K197 VanDerWaalsContact C-N 3.26Å; R195-K197 PolarHBondContact O-N 3.18Å; K197-F199 VanDerWaalsContact C-N 3.34Å; K197-A200 PolarHBondContact O-N 3.18Å; K197-A201 WeakPolarHBondContact O-CB 3.25Å; K197-A201 PolarHBondContact O-N 3.05Å
198	S	79.6	Confident	69.6	Low	56 Å²	56	87.7 Å²	87.7	39%	0.392	51%	0.512	S	S	.	.	H	α-helix	trans	-62.7	-40.5	177.7	70.7	0	0	0	0	112.1	E194 R195 A201	E194-S198 PolarHBondContact O-N 3.09Å; R195-S198 PolarHBondContact O-N 2.86Å; R195-S198 PolarHBondContact O-OG 3.28Å; S198-A201 PolarHBondContact O-N 2.77Å
199	F	75.6	Confident	66.7	Low	135 Å²	135	97.5 Å²	97.5	59%	0.592	56%	0.555	S	S	*	*	H	α-helix	trans	-64.4	-42	172.9	-79.8	-73.3	0	0	0	112.2	R195 K197 A201 G202	R195-F199 HydrophobicContact CG-CD2 3.87Å; R195-F199 HydrophobicContact CG-CE2 3.57Å; R195-F199 VanDerWaalsContact O-CD2 3.23Å; R195-F199 WeakPolarHBondContact O-CD2 3.28Å; R195-F199 PolarHBondContact O-N 3.05Å; R195-F199 VanDerWaalsContact O-N 3.08Å; K197-F199 VanDerWaalsContact C-N 3.34Å; F199-A201 VanDerWaalsContact C-N 3.3Å; F199-A201 PolarHBondContact O-N 3.48Å; F199-G202 PolarHBondContact O-N 3.44Å
200	A	75.9	Confident	63.9	Low	90 Å²	90	101.9 Å²	101.9	74%	0.744	59%	0.585	S	S	*	*	H	α-helix	trans	-69	-26.6	178.4	0	0	0	0	0	113.4	L196 K197 G202	L196-A200 WeakPolarHBondContact O-CB 3.34Å; L196-A200 PolarHBondContact O-N 2.91Å; K197-A200 PolarHBondContact O-N 3.18Å; A200-G202 PolarHBondContact O-N 3.23Å
201	A	76	Confident	61.4	Low	86 Å²	86	102.8 Å²	102.8	71%	0.711	58%	0.583	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.7	6.7	179.3	0	0	0	0	0	114.1	K197 S198 F199 G203	K197-A201 WeakPolarHBondContact O-CB 3.25Å; K197-A201 PolarHBondContact O-N 3.05Å; S198-A201 PolarHBondContact O-N 2.77Å; F199-A201 VanDerWaalsContact C-N 3.3Å; F199-A201 PolarHBondContact O-N 3.48Å; A201-G203 VanDerWaalsContact C-N 3.35Å; A201-G203 PolarHBondContact O-N 3.4Å
202	G	56.7	Low	59	Low	66 Å²	66	107.2 Å²	107.2	68%	0.68	61%	0.614	S	S	*	*	T	Hydrogen-bonded Turn	trans	75.7	19.3	175.8	0	0	0	0	0	114.7	F199 A200 G204	F199-G202 PolarHBondContact O-N 3.44Å; A200-G202 PolarHBondContact O-N 3.23Å; G202-G204 VanDerWaalsContact C-N 3.33Å; G202-G204 PolarHBondContact O-N 3.27Å
203	G	52.9	Low	57	Low	57 Å²	57	110.3 Å²	110.3	59%	0.588	64%	0.638	S	S	*	*			trans	-65.9	89.8	171.3	0	0	0	0	0	110.8	A201	A201-G203 VanDerWaalsContact C-N 3.35Å; A201-G203 PolarHBondContact O-N 3.4Å
204	G	40.6	Very low	55.4	Low	63 Å²	63	107.5 Å²	107.5	65%	0.649	63%	0.628	S	S	*	*			trans	-58.1	158	169.9	0	0	0	0	0	112	G202 E206	G202-G204 VanDerWaalsContact C-N 3.33Å; G202-G204 PolarHBondContact O-N 3.27Å; G204-E206 PolarHBondContact O-N 3.14Å
205	A	44.2	Very low	53.9	Low	111 Å²	111	104.6 Å²	104.6	92%	0.917	62%	0.619	S	S	*	*	T	Hydrogen-bonded Turn	trans	-62.6	24.8	-164.9	0	0	0	0	0	118.1
206	E	35.3	Very low	52.9	Low	192 Å²	192	104.2 Å²	104.2	90%	0.897	62%	0.623	S	S	*	*	T	Hydrogen-bonded Turn	trans	-105.1	-1.2	-171.5	-75.3	-161.5	147	0	0	116.8	G204	G204-E206 PolarHBondContact O-N 3.14Å
207	E	33.5	Very low	52.1	Low	182 Å²	182	102.6 Å²	102.6	85%	0.85	61%	0.613	S	S	*	*	S	Bend	trans	-128.6	24.1	-178.4	-125.8	-177.3	-167.3	0	0	116.6
208	H	37.4	Very low	51.4	Low	121 Å²	121	98.8 Å²	98.8	56%	0.56	60%	0.603	S	S	*	*			trans	-118.8	42.9	-179.1	-119.5	-53.1	0	0	0	115.2	T210 D211	H208-T210 PolarHBondContact O-N 3.39Å; H208-D211 WeakPolarHBondContact CE1-CB 3.47Å; H208-D211 IonicContact CE1-OD1 3.32Å; H208-D211 IonicContact CE1-OD2 2.8Å; H208-D211 PolarHBondContact CE1-OD2 2.92Å; H208-D211 WeakPolarHBondContact ND1-CB 3.37Å; H208-D211 IonicContact ND1-OD2 3.68Å; H208-D211 IonicContact NE2-OD2 3.39Å
209	K	29.9	Very low	51	Low	209 Å²	209	98.6 Å²	98.6	91%	0.909	60%	0.6	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.6	-0.3	167.4	-109.8	174.7	-179.4	169.6	0	113.9
210	T	30.5	Very low	51.1	Low	117 Å²	117	97.8 Å²	97.8	72%	0.718	60%	0.601	S	S	*	*	T	Hydrogen-bonded Turn	trans	-111.1	0.4	-178.7	31.8	0	0	0	0	115.7	H208	H208-T210 PolarHBondContact O-N 3.39Å
211	D	36.7	Very low	51.3	Low	64 Å²	64	96.8 Å²	96.8	34%	0.342	58%	0.584	S	S	.	*			trans	-97.8	16.2	170.9	-103.1	5.1	0	0	0	114.3	H208 S213 R214	H208-D211 WeakPolarHBondContact CE1-CB 3.47Å; H208-D211 IonicContact CE1-OD1 3.32Å; H208-D211 IonicContact CE1-OD2 2.8Å; H208-D211 PolarHBondContact CE1-OD2 2.92Å; H208-D211 WeakPolarHBondContact ND1-CB 3.37Å; H208-D211 IonicContact ND1-OD2 3.68Å; H208-D211 IonicContact NE2-OD2 3.39Å; D211-S213 PolarHBondContact O-N 3.06Å; D211-R214 PolarHBondContact O-N 3.27Å; D211-R214 IonicContact OD2-CZ 3.37Å; D211-R214 IonicContact OD2-NH1 2.84Å; D211-R214 PolarHBondContact OD2-NH1 3.33Å; D211-R214 IonicContact OD2-NH2 3.85Å; D211-R214 PolarHBondContact OD2-NH2 3.46Å
212	S	32.8	Very low	51.4	Low	116 Å²	116	92.8 Å²	92.8	81%	0.811	55%	0.55	S	S	*	*	T	Hydrogen-bonded Turn	trans	-63.5	8.6	175.1	-170.5	0	0	0	0	114.5
213	S	43.8	Very low	52.6	Low	85 Å²	85	93.3 Å²	93.3	59%	0.594	54%	0.536	S	S	*	.	T	Hydrogen-bonded Turn	trans	-104.6	12	-176.9	-9.5	0	0	0	0	113.8	D211	D211-S213 PolarHBondContact O-N 3.06Å
214	R	50.8	Low	54.2	Low	67 Å²	67	95.3 Å²	95.3	25%	0.253	53%	0.533	S	S	.	.			trans	-93.5	108.2	164.9	-67	-167.1	-173.8	102.2	4.1	108.8	C191 D211 L216	C191-R214 PolarHBondContact SG-NH2 2.87Å; D211-R214 PolarHBondContact O-N 3.27Å; D211-R214 IonicContact OD2-CZ 3.37Å; D211-R214 IonicContact OD2-NH1 2.84Å; D211-R214 PolarHBondContact OD2-NH1 3.33Å; D211-R214 IonicContact OD2-NH2 3.85Å; D211-R214 PolarHBondContact OD2-NH2 3.46Å; R214-L216 PolarHBondContact O-N 3.2Å; R214-L216 VanDerWaalsContact O-N 3.1Å
215	V	54.2	Low	56.2	Low	74 Å²	74	95.3 Å²	95.3	45%	0.448	52%	0.515	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.8	98.5	175	-176.9	0	0	0	0	107.5	Y217	V215-Y217 HydrophobicContact CB-CD2 4.42Å; V215-Y217 HydrophobicContact CB-CE2 3.95Å; V215-Y217 HydrophobicContact CG1-CD2 4.01Å; V215-Y217 HydrophobicContact CG1-CE2 3.66Å; V215-Y217 WeakPolarHBondContact O-CD2 3.26Å; V215-Y217 PolarHBondContact O-N 2.66Å
216	L	58	Low	58.1	Low	89 Å²	89	90.8 Å²	90.8	47%	0.466	48%	0.476	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-70	115.3	169.5	-159.2	79.3	0	0	0	107.9	R214 S218	R214-L216 PolarHBondContact O-N 3.2Å; R214-L216 VanDerWaalsContact O-N 3.1Å; L216-S218 PolarHBondContact O-N 3.45Å
217	Y	64.6	Low	60.6	Low	41 Å²	41	86.9 Å²	86.9	16%	0.161	46%	0.46	C	S	.	.			trans	-81.9	107	-177.7	-83.7	-96.9	0	0	0	110.6	V215 N221 I222 I331	V215-Y217 HydrophobicContact CB-CD2 4.42Å; V215-Y217 HydrophobicContact CB-CE2 3.95Å; V215-Y217 HydrophobicContact CG1-CD2 4.01Å; V215-Y217 HydrophobicContact CG1-CE2 3.66Å; V215-Y217 WeakPolarHBondContact O-CD2 3.26Å; V215-Y217 PolarHBondContact O-N 2.66Å; Y217-N221 HydrophobicContact CD1-CB 4.01Å; Y217-I222 HydrophobicContact CD1-CG1 3.89Å; Y217-I222 HydrophobicContact CG-CG1 4.37Å; Y217-I331 HydrophobicContact CD2-CG2 3.73Å; Y217-I331 HydrophobicContact CE2-CB 4.25Å; Y217-I331 HydrophobicContact CE2-CD1 3.65Å; Y217-I331 HydrophobicContact CE2-CG1 3.86Å; Y217-I331 HydrophobicContact CE2-CG2 3.65Å; Y217-I331 WeakPolarHBondContact OH-CD1 3.07Å
218	S	69.6	Low	63.2	Low	53 Å²	53	81.8 Å²	81.8	37%	0.371	44%	0.441	S	S	.	.			trans	-63.5	148.7	161.4	177	0	0	0	0	110.2	L216 L220 N221 I222	L216-S218 PolarHBondContact O-N 3.45Å; S218-L220 PolarHBondContact O-N 2.99Å; S218-L220 VanDerWaalsContact O-N 3.1Å; S218-N221 WeakPolarHBondContact O-CB 3.18Å; S218-N221 PolarHBondContact O-N 3.07Å; S218-I222 PolarHBondContact O-N 3.43Å
219	P	72.6	Confident	65.5	Low	52 Å²	52	79.6 Å²	79.6	34%	0.338	43%	0.432	S	S	.	.	H	α-helix	trans	-50.2	-34	173	-27.2	33.5	0	0	0	113.7	I222 I223 I338	P219-I222 PolarHBondContact O-N 3.33Å; P219-I223 PolarHBondContact O-N 2.96Å; P219-I338 HydrophobicContact CG-CG1 4.31Å
220	L	76.3	Confident	68.1	Low	119 Å²	119	71.4 Å²	71.4	62%	0.623	40%	0.401	S	S	*	.	H	α-helix	trans	-67.7	-41.2	175.7	-72	171.8	0	0	0	112.4	S218 I222 I223 I224	S218-L220 PolarHBondContact O-N 2.99Å; S218-L220 VanDerWaalsContact O-N 3.1Å; L220-I222 PolarHBondContact O-N 3.03Å; L220-I223 PolarHBondContact O-N 2.96Å; L220-I224 WeakPolarHBondContact O-CG1 2.99Å; L220-I224 PolarHBondContact O-N 3.44Å
221	N	80.1	Confident	70.8	Confident	69 Å²	69	67.8 Å²	67.8	37%	0.369	39%	0.386	S	S	.	.	H	α-helix	trans	-62.2	-31.1	178.2	-65.2	-7.2	0	0	0	111.5	Y217 S218 F225	Y217-N221 HydrophobicContact CD1-CB 4.01Å; S218-N221 WeakPolarHBondContact O-CB 3.18Å; S218-N221 PolarHBondContact O-N 3.07Å; N221-F225 WeakPolarHBondContact O-CB 3.44Å; N221-F225 PolarHBondContact O-N 2.85Å
222	I	79.8	Confident	73.2	Confident	1 Å²	1	68.1 Å²	68.1	1%	0.005	39%	0.387	C	S	.	.	H	α-helix	trans	-71	-44.2	176.5	-74.5	160.3	0	0	0	111.8	Y217 S218 P219 L220 I224 F225 V226 I338 L342 L345	Y217-I222 HydrophobicContact CD1-CG1 3.89Å; Y217-I222 HydrophobicContact CG-CG1 4.37Å; S218-I222 PolarHBondContact O-N 3.43Å; P219-I222 PolarHBondContact O-N 3.33Å; L220-I222 PolarHBondContact O-N 3.03Å; I222-I224 VanDerWaalsContact C-N 3.32Å; I222-I224 PolarHBondContact O-N 2.99Å; I222-F225 WeakPolarHBondContact O-CB 3.43Å; I222-F225 PolarHBondContact O-N 3.09Å; I222-V226 WeakPolarHBondContact O-CG2 2.94Å; I222-V226 PolarHBondContact O-N 3.16Å; I222-I338 HydrophobicContact CD1-CB 4.45Å; I222-I338 HydrophobicContact CD1-CG2 3.07Å; I222-L342 HydrophobicContact CD1-CB 4.33Å; I222-L342 HydrophobicContact CG1-CD1 4.33Å; I222-L342 HydrophobicContact CG2-CB 3.98Å; I222-L342 HydrophobicContact CG2-CD1 3.58Å; I222-L342 HydrophobicContact CG2-CG 4.38Å; I222-L345 HydrophobicContact CG2-CD1 4.43Å
223	I	81.8	Confident	75.6	Confident	77 Å²	77	63.8 Å²	63.8	40%	0.395	35%	0.354	S	S	.	.	H	α-helix	trans	-62.3	-45.6	177.3	-65.1	168.2	0	0	0	109.5	P219 L220 F225 V226 I227 L345	P219-I223 PolarHBondContact O-N 2.96Å; L220-I223 PolarHBondContact O-N 2.96Å; I223-F225 VanDerWaalsContact C-N 3.33Å; I223-F225 PolarHBondContact O-N 3.26Å; I223-V226 PolarHBondContact O-N 3.1Å; I223-I227 HydrophobicContact CG2-CD1 3.85Å; I223-I227 VanDerWaalsContact O-CG1 3.29Å; I223-I227 WeakPolarHBondContact O-CG1 3.26Å; I223-I227 PolarHBondContact O-N 3.23Å; I223-L345 HydrophobicContact CG1-CD1 4.23Å
224	I	85.6	Confident	77.6	Confident	100 Å²	100	62.4 Å²	62.4	51%	0.513	34%	0.343	S	S	.	.	H	α-helix	trans	-59.5	-45.5	175.2	-65.9	167.2	0	0	0	110.6	L220 I222 V226 I227 V228	L220-I224 WeakPolarHBondContact O-CG1 2.99Å; L220-I224 PolarHBondContact O-N 3.44Å; I222-I224 VanDerWaalsContact C-N 3.32Å; I222-I224 PolarHBondContact O-N 2.99Å; I224-V226 PolarHBondContact O-N 3.28Å; I224-I227 PolarHBondContact O-N 3.46Å; I224-V228 HydrophobicContact CG2-CG2 4.33Å; I224-V228 WeakPolarHBondContact O-CG2 3.42Å; I224-V228 PolarHBondContact O-N 3.23Å
225	F	83.3	Confident	79.3	Confident	63 Å²	63	62.6 Å²	62.6	28%	0.276	35%	0.348	S	S	.	.	H	α-helix	trans	-57.4	-47.4	177.7	173.4	-99.3	0	0	0	112.2	N221 I222 I223 V228 M229	N221-F225 WeakPolarHBondContact O-CB 3.44Å; N221-F225 PolarHBondContact O-N 2.85Å; I222-F225 WeakPolarHBondContact O-CB 3.43Å; I222-F225 PolarHBondContact O-N 3.09Å; I223-F225 VanDerWaalsContact C-N 3.33Å; I223-F225 PolarHBondContact O-N 3.26Å; F225-V228 PolarHBondContact O-N 3.18Å; F225-M229 HydrophobicContact CD1-CG 4.39Å; F225-M229 HydrophobicContact CE1-CG 3.98Å; F225-M229 HydrophobicContact CE2-CE 4.07Å; F225-M229 HydrophobicContact CE2-CG 4.2Å; F225-M229 HydrophobicContact CE2-SD 4.36Å; F225-M229 HydrophobicContact CZ-CE 4.41Å; F225-M229 HydrophobicContact CZ-CG 3.88Å; F225-M229 HydrophobicContact CZ-SD 4.1Å; F225-M229 VanDerWaalsContact O-CG 3.31Å; F225-M229 WeakPolarHBondContact O-CG 3.39Å; F225-M229 PolarHBondContact O-N 3.01Å
226	V	84.2	Confident	80.7	Confident	15 Å²	15	59.6 Å²	59.6	9%	0.091	33%	0.329	C	S	.	.	H	α-helix	trans	-64.3	-42	178.1	175.2	0	0	0	0	111	I222 I223 I224 V228 M229 C230 L345 L346	I222-V226 WeakPolarHBondContact O-CG2 2.94Å; I222-V226 PolarHBondContact O-N 3.16Å; I223-V226 PolarHBondContact O-N 3.1Å; I224-V226 PolarHBondContact O-N 3.28Å; V226-V228 VanDerWaalsContact C-N 3.34Å; V226-V228 PolarHBondContact O-N 3.42Å; V226-M229 PolarHBondContact O-N 3.44Å; V226-C230 PolarHBondContact O-N 2.7Å; V226-C230 PolarHBondContact O-SG 3.41Å; V226-L345 HydrophobicContact CG2-CB 4.29Å; V226-L346 HydrophobicContact CG2-CD2 4.12Å; V226-L346 HydrophobicContact CG2-CG 4.42Å
227	I	87.3	Confident	81.9	Confident	110 Å²	110	59.3 Å²	59.3	56%	0.564	32%	0.322	S	S	*	.	H	α-helix	trans	-61.2	-43.7	176.5	-69	167.5	0	0	0	111	I223 I224 C230 G231	I223-I227 HydrophobicContact CG2-CD1 3.85Å; I223-I227 VanDerWaalsContact O-CG1 3.29Å; I223-I227 WeakPolarHBondContact O-CG1 3.26Å; I223-I227 PolarHBondContact O-N 3.23Å; I224-I227 PolarHBondContact O-N 3.46Å; I227-C230 PolarHBondContact O-N 3.26Å; I227-G231 PolarHBondContact O-N 2.92Å
228	V	87.9	Confident	82.8	Confident	76 Å²	76	64.1 Å²	64.1	46%	0.461	35%	0.345	S	S	.	.	H	α-helix	trans	-63.7	-41.5	176.6	171.1	0	0	0	0	110.9	I224 F225 V226 G231 M232	I224-V228 HydrophobicContact CG2-CG2 4.33Å; I224-V228 WeakPolarHBondContact O-CG2 3.42Å; I224-V228 PolarHBondContact O-N 3.23Å; F225-V228 PolarHBondContact O-N 3.18Å; V226-V228 VanDerWaalsContact C-N 3.34Å; V226-V228 PolarHBondContact O-N 3.42Å; V228-G231 PolarHBondContact O-N 2.87Å; V228-M232 HydrophobicContact CG1-CG 4.24Å; V228-M232 WeakPolarHBondContact O-CB 3.27Å; V228-M232 VanDerWaalsContact O-CG 3.27Å; V228-M232 WeakPolarHBondContact O-CG 3.37Å; V228-M232 PolarHBondContact O-N 3.48Å
229	M	84.8	Confident	83.5	Confident	74 Å²	74	67.5 Å²	67.5	37%	0.365	35%	0.353	S	S	.	.	H	α-helix	trans	-60.5	-46.3	174.8	-70.5	-70	107.9	0	0	111.8	F225 V226 G231 M232 L233	F225-M229 HydrophobicContact CD1-CG 4.39Å; F225-M229 HydrophobicContact CE1-CG 3.98Å; F225-M229 HydrophobicContact CE2-CE 4.07Å; F225-M229 HydrophobicContact CE2-CG 4.2Å; F225-M229 HydrophobicContact CE2-SD 4.36Å; F225-M229 HydrophobicContact CZ-CE 4.41Å; F225-M229 HydrophobicContact CZ-CG 3.88Å; F225-M229 HydrophobicContact CZ-SD 4.1Å; F225-M229 VanDerWaalsContact O-CG 3.31Å; F225-M229 WeakPolarHBondContact O-CG 3.39Å; F225-M229 PolarHBondContact O-N 3.01Å; V226-M229 PolarHBondContact O-N 3.44Å; M229-G231 PolarHBondContact O-N 3.32Å; M229-M232 PolarHBondContact O-N 3.49Å; M229-L233 PolarHBondContact O-N 2.85Å
230	C	84.8	Confident	84	Confident	38 Å²	38	65.8 Å²	65.8	26%	0.257	34%	0.34	S	S	.	.	H	α-helix	trans	-59	-47.4	174.5	-66.9	0	0	0	0	111.7	V226 I227 L233 V234 Y349 F353	V226-C230 PolarHBondContact O-N 2.7Å; V226-C230 PolarHBondContact O-SG 3.41Å; I227-C230 PolarHBondContact O-N 3.26Å; C230-L233 PolarHBondContact O-N 3.23Å; C230-V234 WeakPolarHBondContact O-CG2 3.48Å; C230-V234 PolarHBondContact O-N 2.83Å; C230-V234 VanDerWaalsContact O-N 3.09Å; C230-Y349 VanDerWaalsContact SG-CD2 3.54Å; C230-F353 HydrophobicContact CB-CE2 4.5Å
231	G	88.4	Confident	84.3	Confident	40 Å²	40	66 Å²	66	41%	0.412	34%	0.341	S	S	.	.	H	α-helix	trans	-60.8	-45.4	179	0	0	0	0	0	111.9	I227 V228 M229 L233 V234 L235	I227-G231 PolarHBondContact O-N 2.92Å; V228-G231 PolarHBondContact O-N 2.87Å; M229-G231 PolarHBondContact O-N 3.32Å; G231-L233 PolarHBondContact O-N 2.58Å; G231-V234 PolarHBondContact O-N 3.11Å; G231-L235 WeakPolarHBondContact O-CB 3.44Å; G231-L235 PolarHBondContact O-N 3.21Å
232	M	85.8	Confident	84.6	Confident	71 Å²	71	67.3 Å²	67.3	35%	0.35	35%	0.352	S	S	.	.	H	α-helix	trans	-64	-39.7	178	-74.7	-59.1	-59.4	0	0	112.5	V228 M229 L235 M236 L243	V228-M232 HydrophobicContact CG1-CG 4.24Å; V228-M232 WeakPolarHBondContact O-CB 3.27Å; V228-M232 VanDerWaalsContact O-CG 3.27Å; V228-M232 WeakPolarHBondContact O-CG 3.37Å; V228-M232 PolarHBondContact O-N 3.48Å; M229-M232 PolarHBondContact O-N 3.49Å; M232-L235 HydrophobicContact SD-CD2 4.47Å; M232-M236 VanDerWaalsContact O-CB 3.25Å; M232-M236 WeakPolarHBondContact O-CB 3.15Å; M232-M236 PolarHBondContact O-N 3.18Å; M232-L243 HydrophobicContact CE-CD2 4.32Å
233	L	84.1	Confident	84.9	Confident	25 Å²	25	68 Å²	68	13%	0.131	36%	0.356	C	S	.	.	H	α-helix	trans	-61.9	-48.6	174.7	-87.8	-153.5	0	0	0	112.6	M229 C230 G231 L235 M236 Y237 Y349 F353 V371	M229-L233 PolarHBondContact O-N 2.85Å; C230-L233 PolarHBondContact O-N 3.23Å; G231-L233 PolarHBondContact O-N 2.58Å; L233-L235 VanDerWaalsContact C-N 3.34Å; L233-M236 HydrophobicContact CD2-CE 3.64Å; L233-M236 PolarHBondContact O-N 3.11Å; L233-Y237 PolarHBondContact O-N 2.8Å; L233-Y237 VanDerWaalsContact O-N 3.09Å; L233-Y349 HydrophobicContact CD1-CE2 3.84Å; L233-Y349 WeakPolarHBondContact CD1-OH 3.36Å; L233-Y349 HydrophobicContact CG-CE2 4.46Å; L233-Y349 VanDerWaalsContact CG-OH 3.27Å; L233-Y349 WeakPolarHBondContact CG-OH 3.27Å; L233-F353 HydrophobicContact CB-CE1 4.31Å; L233-F353 HydrophobicContact CB-CZ 4.33Å; L233-F353 HydrophobicContact CD1-CD1 3.99Å; L233-F353 HydrophobicContact CD1-CD2 4.3Å; L233-F353 HydrophobicContact CD1-CE1 4.05Å; L233-F353 HydrophobicContact CD1-CE2 4.36Å; L233-F353 HydrophobicContact CD1-CG 4.12Å; L233-F353 HydrophobicContact CD1-CZ 4.24Å; L233-V371 HydrophobicContact CD2-CG1 4.23Å
234	V	85.4	Confident	85.1	Confident	57 Å²	57	64.5 Å²	64.5	35%	0.345	34%	0.337	S	S	.	.	H	α-helix	trans	-66.7	-39.7	-180	175.3	0	0	0	0	110.5	C230 G231 M236 Y237 F238 F353	C230-V234 WeakPolarHBondContact O-CG2 3.48Å; C230-V234 PolarHBondContact O-N 2.83Å; C230-V234 VanDerWaalsContact O-N 3.09Å; G231-V234 PolarHBondContact O-N 3.11Å; V234-M236 VanDerWaalsContact C-N 3.28Å; V234-M236 PolarHBondContact O-N 3.42Å; V234-Y237 WeakPolarHBondContact O-CB 3.2Å; V234-Y237 PolarHBondContact O-N 3.39Å; V234-F238 HydrophobicContact CG1-CD2 4.14Å; V234-F238 HydrophobicContact CG1-CE2 3.8Å; V234-F238 VanDerWaalsContact O-CD2 3.24Å; V234-F238 WeakPolarHBondContact O-CD2 3.5Å; V234-F238 PolarHBondContact O-N 3.49Å; V234-F353 HydrophobicContact CG2-CE1 4.12Å; V234-F353 HydrophobicContact CG2-CZ 4.03Å
235	L	87.5	Confident	85.2	Confident	71 Å²	71	65.5 Å²	65.5	37%	0.372	34%	0.336	S	S	.	.	H	α-helix	trans	-61.9	-39.9	175.9	-165.4	79.3	0	0	0	111.1	G231 M232 L233 Y237 F238 F239 L243	G231-L235 WeakPolarHBondContact O-CB 3.44Å; G231-L235 PolarHBondContact O-N 3.21Å; M232-L235 HydrophobicContact SD-CD2 4.47Å; L233-L235 VanDerWaalsContact C-N 3.34Å; L235-Y237 VanDerWaalsContact C-N 3.32Å; L235-Y237 PolarHBondContact O-N 3.39Å; L235-F238 PolarHBondContact O-N 3Å; L235-F238 VanDerWaalsContact O-N 3.17Å; L235-F239 HydrophobicContact CD1-CD2 3.72Å; L235-F239 HydrophobicContact CD1-CE2 3.88Å; L235-F239 HydrophobicContact CG-CD2 3.97Å; L235-F239 PolarHBondContact O-N 2.84Å; L235-L243 VanDerWaalsContact C-CD1 3.48Å; L235-L243 HydrophobicContact CB-CD1 4.02Å; L235-L243 HydrophobicContact CD2-CD1 3.6Å; L235-L243 HydrophobicContact CD2-CD2 3.96Å; L235-L243 HydrophobicContact CD2-CG 4.42Å; L235-L243 HydrophobicContact CG-CD1 3.59Å; L235-L243 WeakPolarHBondContact O-CD1 3.34Å
236	M	83	Confident	85.6	Confident	10 Å²	10	66.3 Å²	66.3	5%	0.049	34%	0.342	C	S	.	.	H	α-helix	trans	-66	-32.4	176.7	-178.7	161.9	47.8	0	0	113.2	M232 L233 V234 F238 Y240 L243 I247 V371 I400	M232-M236 VanDerWaalsContact O-CB 3.25Å; M232-M236 WeakPolarHBondContact O-CB 3.15Å; M232-M236 PolarHBondContact O-N 3.18Å; L233-M236 HydrophobicContact CD2-CE 3.64Å; L233-M236 PolarHBondContact O-N 3.11Å; V234-M236 VanDerWaalsContact C-N 3.28Å; V234-M236 PolarHBondContact O-N 3.42Å; M236-F238 VanDerWaalsContact C-N 3.31Å; M236-F238 PolarHBondContact O-N 2.84Å; M236-Y240 HydrophobicContact CG-CD2 3.88Å; M236-Y240 HydrophobicContact CG-CE2 4.35Å; M236-Y240 WeakPolarHBondContact O-CA 3.47Å; M236-Y240 WeakPolarHBondContact O-CB 3.48Å; M236-Y240 PolarHBondContact O-N 3.32Å; M236-L243 HydrophobicContact CB-CD1 4.3Å; M236-I247 HydrophobicContact CE-CD1 4.25Å; M236-I247 HydrophobicContact SD-CD1 3.55Å; M236-I247 VanDerWaalsContact SD-CD1 3.55Å; M236-V371 HydrophobicContact CE-CB 4.41Å; M236-V371 HydrophobicContact CE-CG1 3.04Å; M236-V371 HydrophobicContact CG-CG1 4.01Å; M236-V371 HydrophobicContact CG-CG2 4.4Å; M236-V371 HydrophobicContact SD-CG1 3.75Å; M236-I400 HydrophobicContact CE-CD1 3.75Å; M236-I400 HydrophobicContact SD-CD1 3.32Å; M236-I400 WeakPolarHBondContact SD-CD1 3.31Å; M236-I400 HydrophobicContact SD-CG1 4.25Å
237	Y	82.9	Confident	85.8	Confident	83 Å²	83	67.1 Å²	67.1	33%	0.325	35%	0.345	S	S	.	.	H	α-helix	trans	-60.9	-39	171	173.2	-94.4	0	0	0	112.2	L233 V234 L235 I367 Q370	L233-Y237 PolarHBondContact O-N 2.8Å; L233-Y237 VanDerWaalsContact O-N 3.09Å; V234-Y237 WeakPolarHBondContact O-CB 3.2Å; V234-Y237 PolarHBondContact O-N 3.39Å; L235-Y237 VanDerWaalsContact C-N 3.32Å; L235-Y237 PolarHBondContact O-N 3.39Å; Y237-I367 HydrophobicContact CD2-CG1 4.15Å; Y237-I367 HydrophobicContact CD2-CG2 4.1Å; Y237-I367 HydrophobicContact CE2-CG1 4.33Å; Y237-I367 HydrophobicContact CG-CG2 4.3Å; Y237-Q370 VanDerWaalsContact CE2-OE1 3.23Å
238	F	83	Confident	85.9	Confident	143 Å²	143	62.4 Å²	62.4	63%	0.627	32%	0.322	S	S	*	.	H	α-helix	trans	-85.1	-35.7	179.2	-68.7	-70.4	0	0	0	114	V234 L235 M236	V234-F238 HydrophobicContact CG1-CD2 4.14Å; V234-F238 HydrophobicContact CG1-CE2 3.8Å; V234-F238 VanDerWaalsContact O-CD2 3.24Å; V234-F238 WeakPolarHBondContact O-CD2 3.5Å; V234-F238 PolarHBondContact O-N 3.49Å; L235-F238 PolarHBondContact O-N 3Å; L235-F238 VanDerWaalsContact O-N 3.17Å; M236-F238 VanDerWaalsContact C-N 3.31Å; M236-F238 PolarHBondContact O-N 2.84Å
239	F	85.9	Confident	86	Confident	123 Å²	123	61.7 Å²	61.7	54%	0.539	32%	0.323	S	S	.	.	S	Bend	trans	-121.6	40.5	-171.7	-57.9	-79.1	0	0	0	112.9	L235 N241 V242 L243	L235-F239 HydrophobicContact CD1-CD2 3.72Å; L235-F239 HydrophobicContact CD1-CE2 3.88Å; L235-F239 HydrophobicContact CG-CD2 3.97Å; L235-F239 PolarHBondContact O-N 2.84Å; F239-N241 VanDerWaalsContact C-N 3.34Å; F239-N241 PolarHBondContact O-N 3.5Å; F239-V242 PolarHBondContact O-N 3.35Å; F239-L243 HydrophobicContact CB-CD1 3.77Å; F239-L243 HydrophobicContact CB-CG 4.23Å; F239-L243 PolarHBondContact O-N 2.86Å; F239-L243 VanDerWaalsContact O-N 3.1Å
240	Y	82.8	Confident	86.4	Confident	16 Å²	16	63.2 Å²	63.2	6%	0.063	33%	0.332	C	S	.	.	H	α-helix	trans	-52	-49	-174.4	-168.1	-90.6	0	0	0	113.2	M236 V242 L243 V244 V371 P375 E398 I400	M236-Y240 HydrophobicContact CG-CD2 3.88Å; M236-Y240 HydrophobicContact CG-CE2 4.35Å; M236-Y240 WeakPolarHBondContact O-CA 3.47Å; M236-Y240 WeakPolarHBondContact O-CB 3.48Å; M236-Y240 PolarHBondContact O-N 3.32Å; Y240-V242 PolarHBondContact O-N 3.26Å; Y240-V242 VanDerWaalsContact O-N 3.07Å; Y240-L243 PolarHBondContact O-N 3.09Å; Y240-V244 HydrophobicContact CE1-CB 4.24Å; Y240-V244 HydrophobicContact CE1-CG1 4.43Å; Y240-V244 HydrophobicContact CE1-CG2 4.31Å; Y240-V244 WeakPolarHBondContact O-CB 3.49Å; Y240-V244 VanDerWaalsContact O-CG1 3.27Å; Y240-V244 WeakPolarHBondContact O-CG1 3.37Å; Y240-V244 PolarHBondContact O-N 3.29Å; Y240-V371 WeakPolarHBondContact CE2-O 3.1Å; Y240-P375 HydrophobicContact CD1-CG 4.09Å; Y240-P375 HydrophobicContact CG-CG 4.27Å; Y240-E398 PolarHBondContact OH-O 2.87Å; Y240-I400 HydrophobicContact CE2-CD1 4.22Å; Y240-I400 HydrophobicContact CE2-CG1 4.48Å
241	N	82.6	Confident	86.7	Confident	123 Å²	123	62 Å²	62	66%	0.658	32%	0.322	S	S	*	.	H	α-helix	trans	-59.7	-24.7	-173.4	-65.3	-21.6	0	0	0	114.4	F239 Y245	F239-N241 VanDerWaalsContact C-N 3.34Å; F239-N241 PolarHBondContact O-N 3.5Å; N241-Y245 WeakPolarHBondContact O-CD2 3.29Å; N241-Y245 WeakPolarHBondContact O-CE2 3.5Å
242	V	86.6	Confident	87	Confident	97 Å²	97	61.4 Å²	61.4	59%	0.588	31%	0.311	S	S	*	.	H	α-helix	trans	-101.1	-45.2	179.1	178.6	0	0	0	0	110.6	F239 Y240 V244 Y245 I246	F239-V242 PolarHBondContact O-N 3.35Å; Y240-V242 PolarHBondContact O-N 3.26Å; Y240-V242 VanDerWaalsContact O-N 3.07Å; V242-V244 VanDerWaalsContact C-N 3.3Å; V242-V244 PolarHBondContact O-N 2.95Å; V242-Y245 PolarHBondContact O-N 3.39Å; V242-I246 HydrophobicContact CG1-CD1 4.16Å; V242-I246 PolarHBondContact O-N 3.15Å
243	L	85.9	Confident	87.3	Confident	17 Å²	17	66 Å²	66	9%	0.089	33%	0.33	C	S	.	.	H	α-helix	trans	-68	-29.8	-174.3	-71.5	168.2	0	0	0	113.1	M232 L235 M236 F239 Y240 Y245 I246 I247	M232-L243 HydrophobicContact CE-CD2 4.32Å; L235-L243 VanDerWaalsContact C-CD1 3.48Å; L235-L243 HydrophobicContact CB-CD1 4.02Å; L235-L243 HydrophobicContact CD2-CD1 3.6Å; L235-L243 HydrophobicContact CD2-CD2 3.96Å; L235-L243 HydrophobicContact CD2-CG 4.42Å; L235-L243 HydrophobicContact CG-CD1 3.59Å; L235-L243 WeakPolarHBondContact O-CD1 3.34Å; M236-L243 HydrophobicContact CB-CD1 4.3Å; F239-L243 HydrophobicContact CB-CD1 3.77Å; F239-L243 HydrophobicContact CB-CG 4.23Å; F239-L243 PolarHBondContact O-N 2.86Å; F239-L243 VanDerWaalsContact O-N 3.1Å; Y240-L243 PolarHBondContact O-N 3.09Å; L243-Y245 VanDerWaalsContact C-N 3.32Å; L243-Y245 PolarHBondContact O-N 3.35Å; L243-I246 HydrophobicContact CD2-CD1 4.2Å; L243-I246 PolarHBondContact O-N 3.01Å; L243-I247 WeakPolarHBondContact O-CG1 3.41Å; L243-I247 PolarHBondContact O-N 3.16Å
244	V	85.7	Confident	87.7	Confident	2 Å²	2	65.9 Å²	65.9	1%	0.012	33%	0.332	C	S	.	.	H	α-helix	trans	-59.1	-43.5	177	69.8	0	0	0	0	111.7	Y240 V242 I246 I247 I248 E398 I400	Y240-V244 HydrophobicContact CE1-CB 4.24Å; Y240-V244 HydrophobicContact CE1-CG1 4.43Å; Y240-V244 HydrophobicContact CE1-CG2 4.31Å; Y240-V244 WeakPolarHBondContact O-CB 3.49Å; Y240-V244 VanDerWaalsContact O-CG1 3.27Å; Y240-V244 WeakPolarHBondContact O-CG1 3.37Å; Y240-V244 PolarHBondContact O-N 3.29Å; V242-V244 VanDerWaalsContact C-N 3.3Å; V242-V244 PolarHBondContact O-N 2.95Å; V244-I246 PolarHBondContact O-N 3.03Å; V244-I247 PolarHBondContact O-N 3.39Å; V244-I248 HydrophobicContact CG2-CD1 4.11Å; V244-I248 WeakPolarHBondContact O-CD1 3.45Å; V244-I248 VanDerWaalsContact O-CG1 3.24Å; V244-I248 WeakPolarHBondContact O-CG1 3.36Å; V244-I248 PolarHBondContact O-N 3.32Å; V244-E398 HydrophobicContact CB-CB 4.37Å; V244-E398 HydrophobicContact CG1-CB 3.83Å; V244-E398 HydrophobicContact CG1-CG 4.35Å; V244-E398 HydrophobicContact CG2-CB 3.63Å; V244-I400 HydrophobicContact CG2-CG1 4.38Å
245	Y	88.3	Confident	88.1	Confident	122 Å²	122	63.1 Å²	63.1	48%	0.478	32%	0.316	S	S	.	.	H	α-helix	trans	-68.4	-35.8	177.7	-65	-74.8	0	0	0	112.5	N241 V242 L243 I248 A249 E398	N241-Y245 WeakPolarHBondContact O-CD2 3.29Å; N241-Y245 WeakPolarHBondContact O-CE2 3.5Å; V242-Y245 PolarHBondContact O-N 3.39Å; L243-Y245 VanDerWaalsContact C-N 3.32Å; L243-Y245 PolarHBondContact O-N 3.35Å; Y245-I248 PolarHBondContact O-N 3.38Å; Y245-A249 WeakPolarHBondContact O-CB 3.33Å; Y245-A249 PolarHBondContact O-N 3.14Å; Y245-E398 HydrophobicContact CE1-CG 4.01Å
246	I	89.9	Confident	88.5	Confident	79 Å²	79	60.4 Å²	60.4	41%	0.405	30%	0.304	S	S	.	.	H	α-helix	trans	-63	-45.7	174.5	-66.1	170.2	0	0	0	110	V242 L243 V244 I248 A249 I250	V242-I246 HydrophobicContact CG1-CD1 4.16Å; V242-I246 PolarHBondContact O-N 3.15Å; L243-I246 HydrophobicContact CD2-CD1 4.2Å; L243-I246 PolarHBondContact O-N 3.01Å; V244-I246 PolarHBondContact O-N 3.03Å; I246-I248 PolarHBondContact O-N 3.23Å; I246-A249 PolarHBondContact O-N 3.11Å; I246-I250 HydrophobicContact CG2-CD1 3.88Å; I246-I250 VanDerWaalsContact O-CG1 3.32Å; I246-I250 WeakPolarHBondContact O-CG1 3.29Å; I246-I250 PolarHBondContact O-N 3.35Å
247	I	88.4	Confident	89	Confident	32 Å²	32	62.3 Å²	62.3	16%	0.164	32%	0.318	C	S	.	.	H	α-helix	trans	-63.7	-41.5	177.7	-67.9	167.2	0	0	0	110.9	M236 L243 V244 A249 I250 F251 I400	M236-I247 HydrophobicContact CE-CD1 4.25Å; M236-I247 HydrophobicContact SD-CD1 3.55Å; M236-I247 VanDerWaalsContact SD-CD1 3.55Å; L243-I247 WeakPolarHBondContact O-CG1 3.41Å; L243-I247 PolarHBondContact O-N 3.16Å; V244-I247 PolarHBondContact O-N 3.39Å; I247-A249 VanDerWaalsContact C-N 3.34Å; I247-A249 PolarHBondContact O-N 3.23Å; I247-I250 PolarHBondContact O-N 3.38Å; I247-F251 VanDerWaalsContact O-CB 3.28Å; I247-F251 WeakPolarHBondContact O-CB 3.45Å; I247-F251 PolarHBondContact O-N 3.14Å; I247-I400 HydrophobicContact CG2-CG2 4.36Å
248	I	89.6	Confident	89.5	Confident	12 Å²	12	58.4 Å²	58.4	6%	0.062	30%	0.303	C	S	.	.	H	α-helix	trans	-60.3	-43.7	175.7	-70.5	163.6	0	0	0	110.8	V244 Y245 I246 F251 C252 W302 P401	V244-I248 HydrophobicContact CG2-CD1 4.11Å; V244-I248 WeakPolarHBondContact O-CD1 3.45Å; V244-I248 VanDerWaalsContact O-CG1 3.24Å; V244-I248 WeakPolarHBondContact O-CG1 3.36Å; V244-I248 PolarHBondContact O-N 3.32Å; Y245-I248 PolarHBondContact O-N 3.38Å; I246-I248 PolarHBondContact O-N 3.23Å; I248-F251 PolarHBondContact O-N 3.23Å; I248-C252 PolarHBondContact O-N 3.22Å; I248-C252 PolarHBondContact O-SG 3.28Å; I248-W302 HydrophobicContact CG2-CZ3 4.21Å; I248-P401 HydrophobicContact CG1-CG 4.43Å
249	A	91.6	Very high	90	Very high	60 Å²	60	52.1 Å²	52.1	50%	0.496	28%	0.276	S	S	.	.	H	α-helix	trans	-64	-45.3	177.7	0	0	0	0	0	112.1	Y245 I246 I247 F251 C252 F253	Y245-A249 WeakPolarHBondContact O-CB 3.33Å; Y245-A249 PolarHBondContact O-N 3.14Å; I246-A249 PolarHBondContact O-N 3.11Å; I247-A249 VanDerWaalsContact C-N 3.34Å; I247-A249 PolarHBondContact O-N 3.23Å; A249-F251 VanDerWaalsContact C-N 3.3Å; A249-F251 PolarHBondContact O-N 3.29Å; A249-C252 PolarHBondContact O-N 2.96Å; A249-F253 PolarHBondContact O-N 3.24Å; A249-F253 VanDerWaalsContact O-N 3.13Å
250	I	91.9	Very high	90.4	Very high	107 Å²	107	48.7 Å²	48.7	55%	0.549	26%	0.261	S	S	.	.	H	α-helix	trans	-59.7	-44	174.8	-67.8	167.3	0	0	0	110.2	I246 I247 C252 F253 A254	I246-I250 HydrophobicContact CG2-CD1 3.88Å; I246-I250 VanDerWaalsContact O-CG1 3.32Å; I246-I250 WeakPolarHBondContact O-CG1 3.29Å; I246-I250 PolarHBondContact O-N 3.35Å; I247-I250 PolarHBondContact O-N 3.38Å; I250-C252 PolarHBondContact O-N 3.45Å; I250-F253 PolarHBondContact O-N 2.96Å; I250-A254 VanDerWaalsContact O-CB 3.27Å; I250-A254 WeakPolarHBondContact O-CB 3.19Å; I250-A254 PolarHBondContact O-N 3.04Å
251	F	91.9	Very high	90.8	Very high	11 Å²	11	49.4 Å²	49.4	5%	0.048	27%	0.268	C	S	.	.	H	α-helix	trans	-62	-43.2	178.6	-177.8	-101.6	0	0	0	111.9	I247 I248 A249 F253 A254 T255 W302 L319 P401 Y426	I247-F251 VanDerWaalsContact O-CB 3.28Å; I247-F251 WeakPolarHBondContact O-CB 3.45Å; I247-F251 PolarHBondContact O-N 3.14Å; I248-F251 PolarHBondContact O-N 3.23Å; A249-F251 VanDerWaalsContact C-N 3.3Å; A249-F251 PolarHBondContact O-N 3.29Å; F251-F253 PolarHBondContact O-N 3.42Å; F251-A254 PolarHBondContact O-N 2.8Å; F251-T255 HydrophobicContact CD1-CG2 4.03Å; F251-T255 HydrophobicContact CD2-CG2 3.71Å; F251-T255 HydrophobicContact CE1-CG2 3.73Å; F251-T255 HydrophobicContact CE2-CG2 3.33Å; F251-T255 HydrophobicContact CG-CG2 4.05Å; F251-T255 HydrophobicContact CZ-CG2 3.38Å; F251-T255 VanDerWaalsContact O-CB 3.28Å; F251-T255 WeakPolarHBondContact O-CB 3.41Å; F251-T255 WeakPolarHBondContact O-CG2 3.16Å; F251-T255 PolarHBondContact O-N 2.93Å; F251-T255 PolarHBondContact O-OG1 2.87Å; F251-W302 HydrophobicContact CD1-CE3 4.05Å; F251-W302 AromaticContact CD1-CH2 3.56Å; F251-W302 HydrophobicContact CD1-CH2 3.56Å; F251-W302 HydrophobicContact CD1-CZ2 4.18Å; F251-W302 AromaticContact CD1-CZ3 3.47Å; F251-W302 HydrophobicContact CD1-CZ3 3.47Å; F251-W302 VanDerWaalsContact CD1-CZ3 3.47Å; F251-W302 HydrophobicContact CE1-CD2 4.27Å; F251-W302 HydrophobicContact CE1-CE3 4.1Å; F251-W302 AromaticContact CE1-CH2 3.75Å; F251-W302 HydrophobicContact CE1-CH2 3.75Å; F251-W302 AromaticContact CE1-CZ2 3.88Å; F251-W302 HydrophobicContact CE1-CZ2 3.88Å; F251-W302 AromaticContact CE1-CZ3 3.85Å; F251-W302 HydrophobicContact CE1-CZ3 3.85Å; F251-L319 HydrophobicContact CZ-CB 4.41Å; F251-P401 HydrophobicContact CB-CG 3.83Å; F251-P401 HydrophobicContact CD1-CB 3.74Å; F251-P401 HydrophobicContact CD1-CG 3.79Å; F251-P401 HydrophobicContact CD2-CB 4.36Å; F251-P401 HydrophobicContact CD2-CG 4.17Å; F251-P401 HydrophobicContact CE1-CB 3.82Å; F251-P401 HydrophobicContact CE1-CG 4.37Å; F251-P401 HydrophobicContact CE2-CB 4.46Å; F251-P401 HydrophobicContact CG-CB 4Å; F251-P401 HydrophobicContact CG-CG 3.65Å; F251-P401 HydrophobicContact CZ-CB 4.18Å; F251-Y426 HydrophobicContact CE2-CD2 4.47Å; F251-Y426 AromaticContact CE2-CE2 3.62Å; F251-Y426 HydrophobicContact CE2-CE2 3.62Å; F251-Y426 HydrophobicContact CZ-CE2 4.07Å
252	C	93.8	Very high	91.2	Very high	28 Å²	28	44.9 Å²	44.9	19%	0.189	25%	0.245	C	C	.	.	H	α-helix	trans	-59.9	-44.6	176.2	-67.4	0	0	0	0	111.9	I248 A249 I250 T255 A256	I248-C252 PolarHBondContact O-N 3.22Å; I248-C252 PolarHBondContact O-SG 3.28Å; A249-C252 PolarHBondContact O-N 2.96Å; I250-C252 PolarHBondContact O-N 3.45Å; C252-T255 PolarHBondContact O-OG1 2.9Å; C252-A256 VanDerWaalsContact O-CB 3.26Å; C252-A256 WeakPolarHBondContact O-CB 3.45Å; C252-A256 PolarHBondContact O-N 3.42Å
253	F	93.1	Very high	91.3	Very high	167 Å²	167	43 Å²	43	73%	0.732	23%	0.232	S	C	*	.	H	α-helix	trans	-67.2	-46.1	178.3	-177.3	-97	0	0	0	112.4	A249 I250 F251 T255 S257	A249-F253 PolarHBondContact O-N 3.24Å; A249-F253 VanDerWaalsContact O-N 3.13Å; I250-F253 PolarHBondContact O-N 2.96Å; F251-F253 PolarHBondContact O-N 3.42Å; F253-T255 PolarHBondContact O-N 2.99Å; F253-S257 PolarHBondContact O-N 3Å; F253-S257 PolarHBondContact O-OG 2.96Å
254	A	92.2	Very high	91.4	Very high	23 Å²	23	44.5 Å²	44.5	19%	0.19	24%	0.24	C	C	.	.	H	α-helix	trans	-64.3	-40	179.7	0	0	0	0	0	111.9	I250 F251 S257 A258 F323	I250-A254 VanDerWaalsContact O-CB 3.27Å; I250-A254 WeakPolarHBondContact O-CB 3.19Å; I250-A254 PolarHBondContact O-N 3.04Å; F251-A254 PolarHBondContact O-N 2.8Å; A254-S257 PolarHBondContact O-OG 3.5Å; A254-A258 WeakPolarHBondContact O-CB 3.49Å; A254-A258 PolarHBondContact O-N 3.39Å; A254-F323 HydrophobicContact CB-CD2 4.12Å; A254-F323 HydrophobicContact CB-CE2 4Å
255	T	94.3	Very high	91.4	Very high	0 Å²	0	46.1 Å²	46.1	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-77.6	-33.9	-179.3	58	0	0	0	0	112.5	F251 C252 F253 A258 L259 L319 F323	F251-T255 HydrophobicContact CD1-CG2 4.03Å; F251-T255 HydrophobicContact CD2-CG2 3.71Å; F251-T255 HydrophobicContact CE1-CG2 3.73Å; F251-T255 HydrophobicContact CE2-CG2 3.33Å; F251-T255 HydrophobicContact CG-CG2 4.05Å; F251-T255 HydrophobicContact CZ-CG2 3.38Å; F251-T255 VanDerWaalsContact O-CB 3.28Å; F251-T255 WeakPolarHBondContact O-CB 3.41Å; F251-T255 WeakPolarHBondContact O-CG2 3.16Å; F251-T255 PolarHBondContact O-N 2.93Å; F251-T255 PolarHBondContact O-OG1 2.87Å; C252-T255 PolarHBondContact O-OG1 2.9Å; F253-T255 PolarHBondContact O-N 2.99Å; T255-A258 PolarHBondContact O-N 3.49Å; T255-L259 WeakPolarHBondContact O-CB 3.41Å; T255-L259 PolarHBondContact O-N 3.07Å; T255-L319 HydrophobicContact CG2-CB 4.08Å; T255-F323 HydrophobicContact CG2-CB 3.97Å; T255-F323 HydrophobicContact CG2-CG 4.45Å
256	A	95.2	Very high	91.3	Very high	14 Å²	14	43.5 Å²	43.5	12%	0.116	25%	0.25	C	S	.	.	H	α-helix	trans	-61.6	-45.4	172.7	0	0	0	0	0	111.9	C252 F260 A299	C252-A256 VanDerWaalsContact O-CB 3.26Å; C252-A256 WeakPolarHBondContact O-CB 3.45Å; C252-A256 PolarHBondContact O-N 3.42Å; A256-F260 WeakPolarHBondContact O-CB 3.28Å; A256-F260 PolarHBondContact O-N 3.32Å; A256-A299 HydrophobicContact CB-CB 4Å
257	S	92.6	Very high	91	Very high	50 Å²	50	41.8 Å²	41.8	35%	0.35	24%	0.242	S	C	.	.	H	α-helix	trans	-68.1	-38.6	176.8	56	0	0	0	0	112.8	F253 A254 S261	F253-S257 PolarHBondContact O-N 3Å; F253-S257 PolarHBondContact O-OG 2.96Å; A254-S257 PolarHBondContact O-OG 3.5Å; S257-S261 PolarHBondContact O-N 3.17Å; S257-S261 PolarHBondContact O-OG 2.95Å
258	A	93.8	Very high	90.5	Very high	0 Å²	0	45 Å²	45	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-66.5	-42.8	175.1	0	0	0	0	0	112.6	A254 T255 S261 C262 A322 N326	A254-A258 WeakPolarHBondContact O-CB 3.49Å; A254-A258 PolarHBondContact O-N 3.39Å; T255-A258 PolarHBondContact O-N 3.49Å; A258-S261 PolarHBondContact O-N 2.94Å; A258-C262 PolarHBondContact O-N 2.87Å; A258-A322 HydrophobicContact CB-CB 4.49Å; A258-N326 HydrophobicContact CB-CB 3.53Å
259	L	94.9	Very high	89.9	Confident	11 Å²	11	51.6 Å²	51.6	6%	0.058	29%	0.294	C	S	.	.	H	α-helix	trans	-64.5	-41.6	176.7	-174.9	63.5	0	0	0	111	T255 S261 C262 L263 C295 V298 L319 A322	T255-L259 WeakPolarHBondContact O-CB 3.41Å; T255-L259 PolarHBondContact O-N 3.07Å; L259-S261 VanDerWaalsContact C-N 3.35Å; L259-S261 PolarHBondContact O-N 3.35Å; L259-C262 PolarHBondContact O-N 2.94Å; L259-L263 HydrophobicContact CD1-CD1 4.15Å; L259-L263 HydrophobicContact CD1-CG 4.15Å; L259-L263 HydrophobicContact CG-CD1 3.95Å; L259-L263 HydrophobicContact CG-CG 4.32Å; L259-L263 WeakPolarHBondContact O-CB 3.49Å; L259-L263 WeakPolarHBondContact O-CG 3.19Å; L259-L263 PolarHBondContact O-N 3.32Å; L259-C295 HydrophobicContact CB-CB 4.47Å; L259-C295 HydrophobicContact CD2-CB 4.26Å; L259-C295 HydrophobicContact CG-CB 4.46Å; L259-V298 HydrophobicContact CD2-CB 4.19Å; L259-V298 HydrophobicContact CD2-CG1 3.97Å; L259-L319 HydrophobicContact CD2-CD2 4.02Å; L259-A322 HydrophobicContact CB-CB 4.29Å; L259-A322 HydrophobicContact CD1-CB 4.12Å
260	F	93.6	Very high	89.3	Confident	52 Å²	52	54.1 Å²	54.1	23%	0.228	30%	0.298	C	S	.	.	H	α-helix	trans	-56.4	-48.9	171.9	175	-92.6	0	0	0	111.4	A256 C262 L263 D264 S288 L291 A292 C295	A256-F260 WeakPolarHBondContact O-CB 3.28Å; A256-F260 PolarHBondContact O-N 3.32Å; F260-C262 VanDerWaalsContact C-N 3.27Å; F260-C262 PolarHBondContact O-N 3.27Å; F260-L263 PolarHBondContact O-N 3.29Å; F260-D264 VanDerWaalsContact O-CB 3.24Å; F260-D264 WeakPolarHBondContact O-CB 3.35Å; F260-D264 PolarHBondContact O-N 2.82Å; F260-S288 WeakPolarHBondContact CZ-OG 3.39Å; F260-L291 HydrophobicContact CD2-CB 4.25Å; F260-L291 HydrophobicContact CD2-CD2 3.82Å; F260-L291 HydrophobicContact CD2-CG 3.88Å; F260-L291 HydrophobicContact CE2-CB 4.15Å; F260-L291 HydrophobicContact CE2-CD2 3.84Å; F260-L291 HydrophobicContact CE2-CG 4.14Å; F260-A292 HydrophobicContact CD2-CB 4.18Å; F260-A292 HydrophobicContact CE2-CB 4.3Å; F260-C295 VanDerWaalsContact CA-SG 3.53Å; F260-C295 HydrophobicContact CB-CB 4.44Å; F260-C295 PolarHBondContact N-SG 2.87Å; F260-C295 VanDerWaalsContact N-SG 3.42Å
261	S	90.1	Very high	88.1	Confident	31 Å²	31	60 Å²	60	22%	0.217	31%	0.313	C	S	.	.	H	α-helix	trans	-62.3	-33.8	179.7	-60.8	0	0	0	0	113.1	W187 S257 A258 L259 A265	W187-S261 WeakPolarHBondContact CZ2-O 3.41Å; S257-S261 PolarHBondContact O-N 3.17Å; S257-S261 PolarHBondContact O-OG 2.95Å; A258-S261 PolarHBondContact O-N 2.94Å; L259-S261 VanDerWaalsContact C-N 3.35Å; L259-S261 PolarHBondContact O-N 3.35Å; S261-A265 PolarHBondContact O-N 2.92Å
262	C	91.1	Very high	86.3	Confident	27 Å²	27	62.9 Å²	62.9	18%	0.182	33%	0.334	C	S	.	.	H	α-helix	trans	-73.5	-51.1	176.8	-169.3	0	0	0	0	112.2	W187 A258 L259 F260 D264 A265 V266	W187-C262 VanDerWaalsContact CH2-CA 3.43Å; W187-C262 HydrophobicContact CH2-CB 3.91Å; W187-C262 HydrophobicContact CZ3-CB 4.2Å; A258-C262 PolarHBondContact O-N 2.87Å; L259-C262 PolarHBondContact O-N 2.94Å; F260-C262 VanDerWaalsContact C-N 3.27Å; F260-C262 PolarHBondContact O-N 3.27Å; C262-D264 VanDerWaalsContact C-N 3.31Å; C262-D264 PolarHBondContact O-N 2.83Å; C262-A265 PolarHBondContact O-N 2.91Å; C262-V266 WeakPolarHBondContact O-CG2 3.2Å; C262-V266 PolarHBondContact O-N 3.04Å
263	L	90.4	Very high	84.4	Confident	57 Å²	57	64.8 Å²	64.8	30%	0.298	36%	0.358	S	S	.	.	H	α-helix	trans	-66.5	-35	-179.3	-66.8	176.7	0	0	0	111.9	L259 F260 V266 L267 L291	L259-L263 HydrophobicContact CD1-CD1 4.15Å; L259-L263 HydrophobicContact CD1-CG 4.15Å; L259-L263 HydrophobicContact CG-CD1 3.95Å; L259-L263 HydrophobicContact CG-CG 4.32Å; L259-L263 WeakPolarHBondContact O-CB 3.49Å; L259-L263 WeakPolarHBondContact O-CG 3.19Å; L259-L263 PolarHBondContact O-N 3.32Å; F260-L263 PolarHBondContact O-N 3.29Å; L263-V266 PolarHBondContact O-N 3.33Å; L263-L267 WeakPolarHBondContact O-CB 3.18Å; L263-L267 VanDerWaalsContact O-CG 3.25Å; L263-L267 WeakPolarHBondContact O-CG 3.41Å; L263-L267 PolarHBondContact O-N 3.34Å; L263-L291 HydrophobicContact CB-CD1 3.67Å; L263-L291 HydrophobicContact CB-CD2 4.09Å; L263-L291 HydrophobicContact CB-CG 4.32Å; L263-L291 HydrophobicContact CD1-CD1 3.77Å; L263-L291 HydrophobicContact CG-CD1 4.38Å
264	D	88.1	Confident	82.6	Confident	49 Å²	49	61.6 Å²	61.6	26%	0.262	35%	0.352	S	S	.	.	H	α-helix	trans	-64.8	-43.8	177.2	-164.8	44.2	0	0	0	111.3	F260 C262 V266 L267 D268 R287 L291	F260-D264 VanDerWaalsContact O-CB 3.24Å; F260-D264 WeakPolarHBondContact O-CB 3.35Å; F260-D264 PolarHBondContact O-N 2.82Å; C262-D264 VanDerWaalsContact C-N 3.31Å; C262-D264 PolarHBondContact O-N 2.83Å; D264-V266 VanDerWaalsContact C-N 3.32Å; D264-V266 PolarHBondContact O-N 3.46Å; D264-L267 PolarHBondContact O-N 2.76Å; D264-D268 PolarHBondContact O-N 2.98Å; D264-R287 PolarHBondContact O-NH2 3.14Å; D264-R287 IonicContact OD1-CZ 3.5Å; D264-R287 IonicContact OD1-NE 3.06Å; D264-R287 IonicContact OD1-NH2 3.53Å; D264-R287 PolarHBondContact OD1-NH2 2.99Å; D264-L291 HydrophobicContact CB-CD2 3.85Å
265	A	84.8	Confident	80.8	Confident	36 Å²	36	66.2 Å²	66.2	30%	0.298	37%	0.373	S	S	.	.	H	α-helix	trans	-62.4	-37.2	173.7	0	0	0	0	0	112.8	W187 S261 C262 L269	W187-A265 HydrophobicContact CH2-CB 4.43Å; W187-A265 HydrophobicContact CZ2-CB 3.61Å; S261-A265 PolarHBondContact O-N 2.92Å; C262-A265 PolarHBondContact O-N 2.91Å; A265-L269 PolarHBondContact O-N 3.43Å
266	V	85.3	Confident	78.9	Confident	68 Å²	68	70.1 Å²	70.1	41%	0.412	40%	0.401	S	S	.	.	H	α-helix	trans	-67.6	-41	174.8	170.8	0	0	0	0	111.2	C262 L263 D264 D268 L269 I270	C262-V266 WeakPolarHBondContact O-CG2 3.2Å; C262-V266 PolarHBondContact O-N 3.04Å; L263-V266 PolarHBondContact O-N 3.33Å; D264-V266 VanDerWaalsContact C-N 3.32Å; D264-V266 PolarHBondContact O-N 3.46Å; V266-D268 VanDerWaalsContact C-N 3.34Å; V266-L269 WeakPolarHBondContact O-CB 3.5Å; V266-L269 PolarHBondContact O-N 3.11Å; V266-I270 HydrophobicContact CG1-CD1 3.73Å; V266-I270 WeakPolarHBondContact O-CG1 3.39Å; V266-I270 PolarHBondContact O-N 2.95Å; V266-I270 VanDerWaalsContact O-N 3.08Å
267	L	83.5	Confident	76.9	Confident	43 Å²	43	75.5 Å²	75.5	23%	0.225	42%	0.422	C	S	.	.	H	α-helix	trans	-68.6	-33.1	178.6	-73.4	172.5	0	0	0	112.5	L263 D264 L269 I270 R271 R287 L291	L263-L267 WeakPolarHBondContact O-CB 3.18Å; L263-L267 VanDerWaalsContact O-CG 3.25Å; L263-L267 WeakPolarHBondContact O-CG 3.41Å; L263-L267 PolarHBondContact O-N 3.34Å; D264-L267 PolarHBondContact O-N 2.76Å; L267-L269 VanDerWaalsContact C-N 3.32Å; L267-I270 PolarHBondContact O-N 3.01Å; L267-R271 PolarHBondContact O-N 3.45Å; L267-R271 VanDerWaalsContact O-N 3.14Å; L267-R287 VanDerWaalsContact CB-CZ 3.41Å; L267-R287 VanDerWaalsContact CB-NH2 3.27Å; L267-R287 HydrophobicContact CD1-CG 4.48Å; L267-L291 HydrophobicContact CD1-CD1 4.07Å; L267-L291 HydrophobicContact CD1-CD2 4Å
268	D	79.5	Confident	74.6	Confident	98 Å²	98	77.1 Å²	77.1	52%	0.524	43%	0.433	S	S	.	.	H	α-helix	trans	-64.8	-36.7	171.5	-74.5	-14.4	0	0	0	112.1	D264 V266 R271 R287	D264-D268 PolarHBondContact O-N 2.98Å; V266-D268 VanDerWaalsContact C-N 3.34Å; D268-R271 PolarHBondContact O-N 2.78Å; D268-R287 IonicContact OD1-CZ 2.75Å; D268-R287 IonicContact OD1-NH1 3.49Å; D268-R287 PolarHBondContact OD1-NH1 2.64Å; D268-R287 IonicContact OD1-NH2 2.8Å; D268-R287 PolarHBondContact OD1-NH2 2.94Å
269	L	76.1	Confident	72.3	Confident	152 Å²	152	81.7 Å²	81.7	80%	0.796	46%	0.461	S	S	*	.	H	α-helix	trans	-66.7	-37.1	174.2	-171.6	66	0	0	0	112.3	A265 V266 L267 R271	A265-L269 PolarHBondContact O-N 3.43Å; V266-L269 WeakPolarHBondContact O-CB 3.5Å; V266-L269 PolarHBondContact O-N 3.11Å; L267-L269 VanDerWaalsContact C-N 3.32Å; L269-R271 PolarHBondContact O-N 3.09Å
270	I	78.8	Confident	69.9	Low	113 Å²	113	92.1 Å²	92.1	58%	0.579	50%	0.501	S	S	*	.	H	α-helix	trans	-78.6	-8.6	-179.8	-62.5	165.9	0	0	0	111.7	V266 L267 C272	V266-I270 HydrophobicContact CG1-CD1 3.73Å; V266-I270 WeakPolarHBondContact O-CG1 3.39Å; V266-I270 PolarHBondContact O-N 2.95Å; V266-I270 VanDerWaalsContact O-N 3.08Å; L267-I270 PolarHBondContact O-N 3.01Å; I270-C272 PolarHBondContact O-N 2.81Å
271	R	66.7	Low	68.1	Low	230 Å²	230	97.8 Å²	97.8	87%	0.868	53%	0.534	S	S	*	.	T	Hydrogen-bonded Turn	trans	56.7	36.1	177.1	-138.6	176.9	-165.9	174.2	3.1	112.7	L267 D268 L269 G273	L267-R271 PolarHBondContact O-N 3.45Å; L267-R271 VanDerWaalsContact O-N 3.14Å; D268-R271 PolarHBondContact O-N 2.78Å; L269-R271 PolarHBondContact O-N 3.09Å; R271-G273 PolarHBondContact O-N 3.49Å
272	C	55.4	Low	66.4	Low	72 Å²	72	103.7 Å²	103.7	49%	0.486	56%	0.555	S	S	.	*	P	Polyproline II helix	trans	-69.9	123.7	177.6	-163.1	0	0	0	0	109.8	I270	I270-C272 PolarHBondContact O-N 2.81Å
273	G	53.9	Low	65	Low	68 Å²	68	108.9 Å²	108.9	70%	0.701	58%	0.581	S	S	*	*	P	Polyproline II helix	trans	-58	144	-171.2	0	0	0	0	0	114.1	R271	R271-G273 PolarHBondContact O-N 3.49Å
274	T	54.7	Low	63.5	Low	99 Å²	99	110.2 Å²	110.2	61%	0.607	59%	0.588	S	S	*	*	P	Polyproline II helix	trans	-98.8	123.4	-179	41.9	0	0	0	0	111.3
275	L	53.3	Low	63	Low	121 Å²	121	109.5 Å²	109.5	63%	0.634	59%	0.587	S	S	*	*			trans	-101.3	115.4	163.2	-111.7	129.7	0	0	0	107.8	F277 V286	L275-F277 HydrophobicContact CD2-CE2 3.84Å; L275-F277 HydrophobicContact CD2-CZ 3.95Å; L275-V286 PolarHBondContact O-N 2.68Å
276	S	55.3	Low	62.8	Low	82 Å²	82	111 Å²	111	57%	0.573	59%	0.592	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-108	139.5	177.4	53.9	0	0	0	0	110.6
277	F	52.9	Low	62.6	Low	126 Å²	126	109.5 Å²	109.5	55%	0.553	58%	0.579	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-120.5	138.8	168.7	-69	-91.8	0	0	0	108.4	L275 L284 V286	L275-F277 HydrophobicContact CD2-CE2 3.84Å; L275-F277 HydrophobicContact CD2-CZ 3.95Å; F277-L284 PolarHBondContact N-O 2.97Å; F277-L284 PolarHBondContact O-N 2.97Å; F277-L284 VanDerWaalsContact O-O 3.12Å; F277-V286 HydrophobicContact CD2-CG2 3.41Å; F277-V286 VanDerWaalsContact CD2-CG2 3.41Å; F277-V286 HydrophobicContact CE2-CG2 3.79Å
278	S	43.8	Very low	62.7	Low	84 Å²	84	109.6 Å²	109.6	59%	0.587	58%	0.584	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-95.7	122.6	177.8	-160.9	0	0	0	0	109.4	N283	S278-N283 PolarHBondContact OG-OD1 2.94Å; S278-N283 VanDerWaalsContact OG-OD1 3.11Å
279	V	45.8	Very low	63	Low	97 Å²	97	109.5 Å²	109.5	59%	0.588	58%	0.582	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-130.1	123	172.6	179.4	0	0	0	0	108.1	N281 K282	V279-N281 PolarHBondContact O-N 3.45Å; V279-K282 PolarHBondContact N-O 3.23Å; V279-K282 PolarHBondContact O-N 3.33Å
280	Y	45.4	Very low	63.6	Low	229 Å²	229	107.5 Å²	107.5	90%	0.898	57%	0.572	S	S	*	*	T	Hydrogen-bonded Turn	trans	52.2	56.5	170.9	-140.3	-95.9	0	0	0	114.1	K282	Y280-K282 PolarHBondContact O-N 2.89Å; Y280-K282 VanDerWaalsContact O-N 3.14Å
281	N	55.9	Low	64.2	Low	171 Å²	171	102.8 Å²	102.8	91%	0.914	55%	0.547	S	S	*	.	T	Hydrogen-bonded Turn	trans	62.5	12.5	178.4	-104.2	1.4	0	0	0	116.4	V279	V279-N281 PolarHBondContact O-N 3.45Å
282	K	53.2	Low	65.4	Low	155 Å²	155	93.3 Å²	93.3	67%	0.674	52%	0.519	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-121.5	127.5	170.6	-68.9	-174.7	179	-179.4	0	110.6	V279 Y280 L284	V279-K282 PolarHBondContact N-O 3.23Å; V279-K282 PolarHBondContact O-N 3.33Å; Y280-K282 PolarHBondContact O-N 2.89Å; Y280-K282 VanDerWaalsContact O-N 3.14Å; K282-L284 PolarHBondContact O-N 3.25Å
283	N	62.6	Low	67.2	Low	136 Å²	136	92.7 Å²	92.7	73%	0.727	52%	0.515	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-79.2	100.5	172	-68.2	-22	0	0	0	108.4	S278	S278-N283 PolarHBondContact OG-OD1 2.94Å; S278-N283 VanDerWaalsContact OG-OD1 3.11Å
284	L	59.7	Low	69.1	Low	86 Å²	86	92.6 Å²	92.6	45%	0.45	50%	0.501	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.2	115.2	176.6	-81.3	145.7	0	0	0	108.6	F277 K282 I289	F277-L284 PolarHBondContact N-O 2.97Å; F277-L284 PolarHBondContact O-N 2.97Å; F277-L284 VanDerWaalsContact O-O 3.12Å; K282-L284 PolarHBondContact O-N 3.25Å; L284-I289 HydrophobicContact CB-CD1 4.21Å; L284-I289 HydrophobicContact CD2-CD1 4.18Å; L284-I289 HydrophobicContact CD2-CG1 4.41Å
285	S	77.2	Confident	71	Confident	34 Å²	34	88 Å²	88	24%	0.238	47%	0.472	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-75.8	124	174.9	-178.2	0	0	0	0	109.6	R287 S288 I289	S285-R287 PolarHBondContact O-N 3.44Å; S285-S288 WeakPolarHBondContact O-CB 3.48Å; S285-S288 PolarHBondContact O-N 3.25Å; S285-I289 PolarHBondContact O-N 3.34Å
286	V	79.6	Confident	73	Confident	66 Å²	66	86.8 Å²	86.8	40%	0.4	47%	0.466	S	S	.	.	H	α-helix	trans	-58.9	-35.7	179.5	177.5	0	0	0	0	110.9	L275 F277 S288 I289 L290	L275-V286 PolarHBondContact O-N 2.68Å; F277-V286 HydrophobicContact CD2-CG2 3.41Å; F277-V286 VanDerWaalsContact CD2-CG2 3.41Å; F277-V286 HydrophobicContact CE2-CG2 3.79Å; V286-S288 VanDerWaalsContact C-N 3.3Å; V286-S288 PolarHBondContact O-N 2.91Å; V286-I289 PolarHBondContact O-N 2.93Å; V286-L290 WeakPolarHBondContact O-CB 3.35Å; V286-L290 PolarHBondContact O-N 3.41Å
287	R	81.8	Confident	74.9	Confident	37 Å²	37	86.6 Å²	86.6	14%	0.14	46%	0.461	C	S	.	.	H	α-helix	trans	-55.4	-44.2	173.6	175.6	-178.6	145.2	-173.4	-14.5	111.7	D264 L267 D268 S285 L291	D264-R287 PolarHBondContact O-NH2 3.14Å; D264-R287 IonicContact OD1-CZ 3.5Å; D264-R287 IonicContact OD1-NE 3.06Å; D264-R287 IonicContact OD1-NH2 3.53Å; D264-R287 PolarHBondContact OD1-NH2 2.99Å; L267-R287 VanDerWaalsContact CB-CZ 3.41Å; L267-R287 VanDerWaalsContact CB-NH2 3.27Å; L267-R287 HydrophobicContact CD1-CG 4.48Å; D268-R287 IonicContact OD1-CZ 2.75Å; D268-R287 IonicContact OD1-NH1 3.49Å; D268-R287 PolarHBondContact OD1-NH1 2.64Å; D268-R287 IonicContact OD1-NH2 2.8Å; D268-R287 PolarHBondContact OD1-NH2 2.94Å; S285-R287 PolarHBondContact O-N 3.44Å; R287-L291 WeakPolarHBondContact O-CB 3.25Å; R287-L291 PolarHBondContact O-N 3.2Å
288	S	84.4	Confident	76.9	Confident	46 Å²	46	82.1 Å²	82.1	32%	0.322	44%	0.444	S	S	.	.	H	α-helix	trans	-68.6	-41.9	-177.7	-176.9	0	0	0	0	111.8	F260 S285 V286 L291 A292	F260-S288 WeakPolarHBondContact CZ-OG 3.39Å; S285-S288 WeakPolarHBondContact O-CB 3.48Å; S285-S288 PolarHBondContact O-N 3.25Å; V286-S288 VanDerWaalsContact C-N 3.3Å; V286-S288 PolarHBondContact O-N 2.91Å; S288-L291 PolarHBondContact O-N 2.84Å; S288-A292 VanDerWaalsContact O-CB 3.29Å; S288-A292 WeakPolarHBondContact O-CB 3.34Å; S288-A292 PolarHBondContact O-N 3.42Å
289	I	87.3	Confident	79.3	Confident	96 Å²	96	78.3 Å²	78.3	49%	0.492	42%	0.418	S	S	.	.	H	α-helix	trans	-65.3	-47	177	-62.3	173.5	0	0	0	110.6	L284 S285 V286 L291 A292 S293	L284-I289 HydrophobicContact CB-CD1 4.21Å; L284-I289 HydrophobicContact CD2-CD1 4.18Å; L284-I289 HydrophobicContact CD2-CG1 4.41Å; S285-I289 PolarHBondContact O-N 3.34Å; V286-I289 PolarHBondContact O-N 2.93Å; I289-L291 VanDerWaalsContact C-N 3.32Å; I289-L291 PolarHBondContact O-N 2.8Å; I289-A292 PolarHBondContact O-N 2.71Å; I289-S293 PolarHBondContact O-N 3.4Å
290	L	88.9	Confident	81.6	Confident	110 Å²	110	77.7 Å²	77.7	58%	0.576	41%	0.414	S	S	*	.	H	α-helix	trans	-61.2	-44.7	178.4	-174.8	136.3	0	0	0	110.6	V286 S293 V294	V286-L290 WeakPolarHBondContact O-CB 3.35Å; V286-L290 PolarHBondContact O-N 3.41Å; L290-S293 PolarHBondContact O-N 2.88Å; L290-S293 PolarHBondContact O-OG 3.25Å; L290-V294 WeakPolarHBondContact O-CG2 3.14Å; L290-V294 PolarHBondContact O-N 3.47Å
291	L	90.3	Very high	83.9	Confident	13 Å²	13	69.9 Å²	69.9	7%	0.068	39%	0.387	C	S	.	.	H	α-helix	trans	-62.7	-45.5	177.3	-173	64	0	0	0	112.4	F260 L263 D264 L267 R287 S288 I289 S293 V294 C295	F260-L291 HydrophobicContact CD2-CB 4.25Å; F260-L291 HydrophobicContact CD2-CD2 3.82Å; F260-L291 HydrophobicContact CD2-CG 3.88Å; F260-L291 HydrophobicContact CE2-CB 4.15Å; F260-L291 HydrophobicContact CE2-CD2 3.84Å; F260-L291 HydrophobicContact CE2-CG 4.14Å; L263-L291 HydrophobicContact CB-CD1 3.67Å; L263-L291 HydrophobicContact CB-CD2 4.09Å; L263-L291 HydrophobicContact CB-CG 4.32Å; L263-L291 HydrophobicContact CD1-CD1 3.77Å; L263-L291 HydrophobicContact CG-CD1 4.38Å; D264-L291 HydrophobicContact CB-CD2 3.85Å; L267-L291 HydrophobicContact CD1-CD1 4.07Å; L267-L291 HydrophobicContact CD1-CD2 4Å; R287-L291 WeakPolarHBondContact O-CB 3.25Å; R287-L291 PolarHBondContact O-N 3.2Å; S288-L291 PolarHBondContact O-N 2.84Å; I289-L291 VanDerWaalsContact C-N 3.32Å; I289-L291 PolarHBondContact O-N 2.8Å; L291-S293 VanDerWaalsContact C-N 3.29Å; L291-S293 PolarHBondContact O-N 3.41Å; L291-V294 PolarHBondContact O-N 3Å; L291-C295 PolarHBondContact O-N 3.27Å; L291-C295 PolarHBondContact O-SG 2.89Å
292	A	91.4	Very high	85.7	Confident	32 Å²	32	62 Å²	62	26%	0.264	34%	0.344	S	S	.	.	H	α-helix	trans	-59.2	-41.7	176.3	0	0	0	0	0	111.4	F260 S288 I289 V294 C295 I296	F260-A292 HydrophobicContact CD2-CB 4.18Å; F260-A292 HydrophobicContact CE2-CB 4.3Å; S288-A292 VanDerWaalsContact O-CB 3.29Å; S288-A292 WeakPolarHBondContact O-CB 3.34Å; S288-A292 PolarHBondContact O-N 3.42Å; I289-A292 PolarHBondContact O-N 2.71Å; A292-V294 VanDerWaalsContact C-N 3.34Å; A292-V294 PolarHBondContact O-N 3.25Å; A292-C295 PolarHBondContact O-N 3.42Å; A292-I296 WeakPolarHBondContact O-CB 3.42Å; A292-I296 VanDerWaalsContact O-CG1 3.25Å; A292-I296 WeakPolarHBondContact O-CG1 3.33Å; A292-I296 PolarHBondContact O-N 3.42Å
293	S	93.3	Very high	87.4	Confident	58 Å²	58	55.1 Å²	55.1	41%	0.406	32%	0.318	S	S	.	.	H	α-helix	trans	-62	-40.9	176.9	77.6	0	0	0	0	112.4	I289 L290 L291 T297	I289-S293 PolarHBondContact O-N 3.4Å; L290-S293 PolarHBondContact O-N 2.88Å; L290-S293 PolarHBondContact O-OG 3.25Å; L291-S293 VanDerWaalsContact C-N 3.29Å; L291-S293 PolarHBondContact O-N 3.41Å; S293-T297 WeakPolarHBondContact O-CB 3.33Å; S293-T297 PolarHBondContact O-N 3.31Å; S293-T297 PolarHBondContact O-OG1 2.92Å
294	V	94.1	Very high	88.8	Confident	67 Å²	67	53.2 Å²	53.2	41%	0.406	31%	0.311	S	S	.	.	H	α-helix	trans	-65	-47.5	176.2	172.2	0	0	0	0	110.4	L290 L291 A292 I296 T297 V298	L290-V294 WeakPolarHBondContact O-CG2 3.14Å; L290-V294 PolarHBondContact O-N 3.47Å; L291-V294 PolarHBondContact O-N 3Å; A292-V294 VanDerWaalsContact C-N 3.34Å; A292-V294 PolarHBondContact O-N 3.25Å; V294-I296 PolarHBondContact O-N 3.41Å; V294-T297 PolarHBondContact O-N 2.95Å; V294-V298 HydrophobicContact CG1-CG2 4.49Å; V294-V298 WeakPolarHBondContact O-CG2 2.86Å; V294-V298 PolarHBondContact O-N 3.27Å
295	C	95.2	Very high	90.1	Very high	1 Å²	1	55 Å²	55	1%	0.007	31%	0.312	C	S	.	.	H	α-helix	trans	-61.3	-43.4	179.8	-65.8	0	0	0	0	112.7	L259 F260 L291 A292 V298 A299	L259-C295 HydrophobicContact CB-CB 4.47Å; L259-C295 HydrophobicContact CD2-CB 4.26Å; L259-C295 HydrophobicContact CG-CB 4.46Å; F260-C295 VanDerWaalsContact CA-SG 3.53Å; F260-C295 HydrophobicContact CB-CB 4.44Å; F260-C295 PolarHBondContact N-SG 2.87Å; F260-C295 VanDerWaalsContact N-SG 3.42Å; L291-C295 PolarHBondContact O-N 3.27Å; L291-C295 PolarHBondContact O-SG 2.89Å; A292-C295 PolarHBondContact O-N 3.42Å; C295-V298 PolarHBondContact O-N 2.8Å; C295-A299 PolarHBondContact O-N 2.73Å
296	I	95.1	Very high	90.3	Very high	96 Å²	96	56.1 Å²	56.1	49%	0.492	31%	0.311	S	S	.	.	H	α-helix	trans	-63.9	-44.5	177	-67.7	165.5	0	0	0	110	A292 V294 V298 A299 V300	A292-I296 WeakPolarHBondContact O-CB 3.42Å; A292-I296 VanDerWaalsContact O-CG1 3.25Å; A292-I296 WeakPolarHBondContact O-CG1 3.33Å; A292-I296 PolarHBondContact O-N 3.42Å; V294-I296 PolarHBondContact O-N 3.41Å; I296-V298 VanDerWaalsContact C-N 3.33Å; I296-V298 PolarHBondContact O-N 3.38Å; I296-A299 PolarHBondContact O-N 2.9Å; I296-V300 HydrophobicContact CG2-CG2 4.21Å; I296-V300 VanDerWaalsContact O-CG2 3.31Å; I296-V300 WeakPolarHBondContact O-CG2 3.12Å; I296-V300 PolarHBondContact O-N 3.33Å
297	T	95.1	Very high	90.2	Very high	78 Å²	78	56 Å²	56	48%	0.479	31%	0.309	S	S	.	.	H	α-helix	trans	-59.2	-45.1	178.6	-57.5	0	0	0	0	111.1	S293 V294 A299 V300 I301	S293-T297 WeakPolarHBondContact O-CB 3.33Å; S293-T297 PolarHBondContact O-N 3.31Å; S293-T297 PolarHBondContact O-OG1 2.92Å; V294-T297 PolarHBondContact O-N 2.95Å; T297-A299 PolarHBondContact O-N 3.42Å; T297-V300 PolarHBondContact O-N 3.46Å; T297-I301 HydrophobicContact CG2-CD1 3.84Å; T297-I301 HydrophobicContact CG2-CG1 4.41Å; T297-I301 WeakPolarHBondContact O-CB 3.31Å; T297-I301 VanDerWaalsContact O-CG1 3.23Å; T297-I301 WeakPolarHBondContact O-CG1 3.44Å; T297-I301 PolarHBondContact O-N 3.23Å
298	V	95.1	Very high	90.1	Very high	33 Å²	33	59.3 Å²	59.3	20%	0.2	33%	0.326	C	S	.	.	H	α-helix	trans	-60.8	-44.8	176.9	171	0	0	0	0	111.7	L259 V294 C295 I296 I301 W302 L315 L319	L259-V298 HydrophobicContact CD2-CB 4.19Å; L259-V298 HydrophobicContact CD2-CG1 3.97Å; V294-V298 HydrophobicContact CG1-CG2 4.49Å; V294-V298 WeakPolarHBondContact O-CG2 2.86Å; V294-V298 PolarHBondContact O-N 3.27Å; C295-V298 PolarHBondContact O-N 2.8Å; I296-V298 VanDerWaalsContact C-N 3.33Å; I296-V298 PolarHBondContact O-N 3.38Å; V298-I301 PolarHBondContact O-N 2.87Å; V298-W302 PolarHBondContact O-N 2.86Å; V298-L315 HydrophobicContact CG1-CD1 3.61Å; V298-L315 HydrophobicContact CG1-CG 4.35Å; V298-L319 HydrophobicContact CG1-CD2 4.14Å
299	A	94.3	Very high	89.4	Confident	4 Å²	4	59.3 Å²	59.3	3%	0.033	32%	0.322	C	S	.	.	H	α-helix	trans	-66	-38.7	178.1	0	0	0	0	0	112.6	A256 C295 I296 T297 W302 G303	A256-A299 HydrophobicContact CB-CB 4Å; C295-A299 PolarHBondContact O-N 2.73Å; I296-A299 PolarHBondContact O-N 2.9Å; T297-A299 PolarHBondContact O-N 3.42Å; A299-W302 PolarHBondContact O-N 3.38Å; A299-G303 PolarHBondContact O-N 3.47Å
300	V	93.9	Very high	88.7	Confident	83 Å²	83	64.6 Å²	64.6	50%	0.503	34%	0.336	S	S	.	.	H	α-helix	trans	-67.8	-43.7	176.4	172.1	0	0	0	0	111.3	I296 T297 W302 G303 V304	I296-V300 HydrophobicContact CG2-CG2 4.21Å; I296-V300 VanDerWaalsContact O-CG2 3.31Å; I296-V300 WeakPolarHBondContact O-CG2 3.12Å; I296-V300 PolarHBondContact O-N 3.33Å; T297-V300 PolarHBondContact O-N 3.46Å; V300-W302 VanDerWaalsContact C-N 3.27Å; V300-W302 PolarHBondContact O-N 3.36Å; V300-G303 PolarHBondContact O-N 3.36Å; V300-G303 VanDerWaalsContact O-N 3.11Å; V300-V304 HydrophobicContact CG1-CG2 4.25Å; V300-V304 WeakPolarHBondContact O-CG2 3.35Å; V300-V304 PolarHBondContact O-N 3.08Å
301	I	94.1	Very high	88.3	Confident	65 Å²	65	64.7 Å²	64.7	33%	0.333	33%	0.329	S	S	.	.	H	α-helix	trans	-56.6	-46.6	174.4	-72.2	167.8	0	0	0	109.8	T297 V298 G303 V304 Y305 W311 L315	T297-I301 HydrophobicContact CG2-CD1 3.84Å; T297-I301 HydrophobicContact CG2-CG1 4.41Å; T297-I301 WeakPolarHBondContact O-CB 3.31Å; T297-I301 VanDerWaalsContact O-CG1 3.23Å; T297-I301 WeakPolarHBondContact O-CG1 3.44Å; T297-I301 PolarHBondContact O-N 3.23Å; V298-I301 PolarHBondContact O-N 2.87Å; I301-G303 PolarHBondContact O-N 3.33Å; I301-V304 PolarHBondContact O-N 3.29Å; I301-Y305 HydrophobicContact CG2-CD2 4.14Å; I301-Y305 WeakPolarHBondContact O-CD2 3.29Å; I301-Y305 PolarHBondContact O-N 3.03Å; I301-W311 HydrophobicContact CG2-CH2 3.78Å; I301-W311 HydrophobicContact CG2-CZ3 4.42Å; I301-L315 HydrophobicContact CB-CD2 4.48Å; I301-L315 HydrophobicContact CG2-CD2 3.96Å
302	W	93.2	Very high	88.1	Confident	5 Å²	5	64.1 Å²	64.1	2%	0.019	33%	0.326	C	S	.	.	H	α-helix	trans	-58.8	-47.3	175.4	179.5	80.8	0	0	0	111.7	I248 F251 V298 A299 V300 V304 R306 I312 L315 L319 P401	I248-W302 HydrophobicContact CG2-CZ3 4.21Å; F251-W302 HydrophobicContact CD1-CE3 4.05Å; F251-W302 AromaticContact CD1-CH2 3.56Å; F251-W302 HydrophobicContact CD1-CH2 3.56Å; F251-W302 HydrophobicContact CD1-CZ2 4.18Å; F251-W302 AromaticContact CD1-CZ3 3.47Å; F251-W302 HydrophobicContact CD1-CZ3 3.47Å; F251-W302 VanDerWaalsContact CD1-CZ3 3.47Å; F251-W302 HydrophobicContact CE1-CD2 4.27Å; F251-W302 HydrophobicContact CE1-CE3 4.1Å; F251-W302 AromaticContact CE1-CH2 3.75Å; F251-W302 HydrophobicContact CE1-CH2 3.75Å; F251-W302 AromaticContact CE1-CZ2 3.88Å; F251-W302 HydrophobicContact CE1-CZ2 3.88Å; F251-W302 AromaticContact CE1-CZ3 3.85Å; F251-W302 HydrophobicContact CE1-CZ3 3.85Å; V298-W302 PolarHBondContact O-N 2.86Å; A299-W302 PolarHBondContact O-N 3.38Å; V300-W302 VanDerWaalsContact C-N 3.27Å; V300-W302 PolarHBondContact O-N 3.36Å; W302-V304 PolarHBondContact O-N 3.44Å; W302-R306 WeakPolarHBondContact O-CA 3.43Å; W302-R306 WeakPolarHBondContact O-CB 3.29Å; W302-R306 PolarHBondContact O-N 3.19Å; W302-I312 HydrophobicContact CG-CD1 4.49Å; W302-L315 HydrophobicContact CB-CD2 3.6Å; W302-L315 HydrophobicContact CB-CG 4.03Å; W302-L315 HydrophobicContact CG-CD2 4.4Å; W302-L315 HydrophobicContact CG-CG 4.5Å; W302-L319 HydrophobicContact CB-CD1 3.58Å; W302-L319 HydrophobicContact CD2-CD1 4.06Å; W302-L319 HydrophobicContact CG-CD1 3.57Å; W302-P401 HydrophobicContact CH2-CB 3.34Å; W302-P401 HydrophobicContact CH2-CG 3.84Å; W302-P401 HydrophobicContact CZ2-CB 3.49Å; W302-P401 VanDerWaalsContact CZ2-CB 3.49Å; W302-P401 HydrophobicContact CZ2-CG 4.46Å; W302-P401 HydrophobicContact CZ3-CB 4.49Å
303	G	89.9	Confident	87.8	Confident	11 Å²	11	64.9 Å²	64.9	11%	0.113	32%	0.322	C	S	.	.	H	α-helix	trans	-62.2	-37.6	-179.8	0	0	0	0	0	114	A299 V300 I301 R306	A299-G303 PolarHBondContact O-N 3.47Å; V300-G303 PolarHBondContact O-N 3.36Å; V300-G303 VanDerWaalsContact O-N 3.11Å; I301-G303 PolarHBondContact O-N 3.33Å; G303-R306 WeakPolarHBondContact O-CD 3.25Å; G303-R306 WeakPolarHBondContact O-CG 3.43Å; G303-R306 PolarHBondContact O-NH1 3.14Å
304	V	90.3	Very high	87.7	Confident	97 Å²	97	66.9 Å²	66.9	59%	0.588	33%	0.327	S	S	*	.	H	α-helix	trans	-75.3	-45.4	179.8	173.1	0	0	0	0	111.6	V300 I301 W302 R306	V300-V304 HydrophobicContact CG1-CG2 4.25Å; V300-V304 WeakPolarHBondContact O-CG2 3.35Å; V300-V304 PolarHBondContact O-N 3.08Å; I301-V304 PolarHBondContact O-N 3.29Å; W302-V304 PolarHBondContact O-N 3.44Å; V304-R306 VanDerWaalsContact C-N 3.35Å
305	Y	87.7	Confident	87.6	Confident	122 Å²	122	64.9 Å²	64.9	48%	0.478	31%	0.314	S	S	.	.	S	Bend	trans	-94	16.7	-176.8	-66.2	-79.6	0	0	0	113.5	I301 N307 E308 W311 I312	I301-Y305 HydrophobicContact CG2-CD2 4.14Å; I301-Y305 WeakPolarHBondContact O-CD2 3.29Å; I301-Y305 PolarHBondContact O-N 3.03Å; Y305-N307 PolarHBondContact O-N 2.52Å; Y305-E308 HydrophobicContact CD1-CG 4.34Å; Y305-E308 WeakPolarHBondContact O-CB 3.29Å; Y305-E308 PolarHBondContact O-N 2.85Å; Y305-W311 HydrophobicContact CD1-CZ2 4.39Å; Y305-W311 HydrophobicContact CD2-CH2 4.46Å; Y305-W311 HydrophobicContact CD2-CZ2 4.25Å; Y305-W311 HydrophobicContact CG-CH2 4.47Å; Y305-W311 AromaticContact CG-CZ2 3.9Å; Y305-W311 HydrophobicContact CG-CZ2 3.9Å; Y305-I312 WeakPolarHBondContact O-CG1 3.41Å
306	R	82.1	Confident	87.4	Confident	58 Å²	58	65 Å²	65	22%	0.219	31%	0.314	C	S	.	.	T	Hydrogen-bonded Turn	trans	-55.1	-26.8	-175	67.1	-175.3	-176.9	-85.2	-5.2	115.2	W302 G303 V304 E308 E398	W302-R306 WeakPolarHBondContact O-CA 3.43Å; W302-R306 WeakPolarHBondContact O-CB 3.29Å; W302-R306 PolarHBondContact O-N 3.19Å; G303-R306 WeakPolarHBondContact O-CD 3.25Å; G303-R306 WeakPolarHBondContact O-CG 3.43Å; G303-R306 PolarHBondContact O-NH1 3.14Å; V304-R306 VanDerWaalsContact C-N 3.35Å; R306-E308 VanDerWaalsContact C-N 3.35Å; R306-E398 IonicContact CZ-OE1 3.49Å; R306-E398 IonicContact CZ-OE2 2.85Å; R306-E398 IonicContact NE-OE1 2.72Å; R306-E398 PolarHBondContact NE-OE1 3.39Å; R306-E398 IonicContact NE-OE2 2.69Å; R306-E398 PolarHBondContact NE-OE2 3.18Å; R306-E398 VanDerWaalsContact NH2-CD 3.34Å; R306-E398 IonicContact NH2-OE1 3.41Å; R306-E398 PolarHBondContact NH2-OE1 3.16Å; R306-E398 IonicContact NH2-OE2 3.47Å; R306-E398 PolarHBondContact NH2-OE2 2.89Å
307	N	77.9	Confident	87.3	Confident	64 Å²	64	60.8 Å²	60.8	34%	0.342	29%	0.293	S	S	.	.	T	Hydrogen-bonded Turn	trans	-87	-4.2	-179.1	-65.9	-24.3	0	0	0	113.1	Y305 D309 P396	Y305-N307 PolarHBondContact O-N 2.52Å; N307-D309 PolarHBondContact O-N 3.28Å; N307-P396 HydrophobicContact CB-CB 4.2Å; N307-P396 HydrophobicContact CB-CG 4.5Å
308	E	78.9	Confident	87.2	Confident	107 Å²	107	61.3 Å²	61.3	50%	0.5	29%	0.292	S	S	.	.			trans	-89.7	83.1	179.9	-71.3	-68.7	178.3	0	0	112.2	Y305 R306 R310 I312	Y305-E308 HydrophobicContact CD1-CG 4.34Å; Y305-E308 WeakPolarHBondContact O-CB 3.29Å; Y305-E308 PolarHBondContact O-N 2.85Å; R306-E308 VanDerWaalsContact C-N 3.35Å; E308-R310 PolarHBondContact O-N 3.18Å; E308-I312 WeakPolarHBondContact O-CB 3.25Å; E308-I312 WeakPolarHBondContact O-CG2 3.41Å; E308-I312 PolarHBondContact O-N 3.16Å
309	D	69.4	Low	87.2	Confident	46 Å²	46	59.7 Å²	59.7	25%	0.246	28%	0.282	C	S	.	.	T	Hydrogen-bonded Turn	trans	-58.8	-17.4	-173.2	-74.1	-39.7	0	0	0	114.7	N307 W311 K399 F421	N307-D309 PolarHBondContact O-N 3.28Å; D309-W311 PolarHBondContact O-N 2.87Å; D309-K399 VanDerWaalsContact CG-NZ 3.33Å; D309-K399 IonicContact OD1-NZ 2.74Å; D309-K399 PolarHBondContact OD1-NZ 3.32Å; D309-K399 IonicContact OD2-NZ 3.41Å; D309-K399 PolarHBondContact OD2-NZ 2.94Å; D309-F421 HydrophobicContact CB-CE2 4.02Å; D309-F421 HydrophobicContact CB-CZ 4.06Å; D309-F421 WeakPolarHBondContact O-CZ 3.41Å
310	R	73.1	Confident	87.2	Confident	207 Å²	207	59.5 Å²	59.5	78%	0.781	28%	0.281	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.6	-39.1	-173.4	-168.9	174.2	-177.1	179.5	1.5	114.5	E308 W313	E308-R310 PolarHBondContact O-N 3.18Å; R310-W313 PolarHBondContact O-NE1 3.43Å; R310-W313 VanDerWaalsContact O-NE1 3.1Å
311	W	80.8	Confident	87.2	Confident	111 Å²	111	57.7 Å²	57.7	42%	0.42	27%	0.268	S	S	.	.	T	Hydrogen-bonded Turn	trans	-132.2	-20.2	-174.8	68	-84.9	0	0	0	113.5	I301 Y305 D309 W313 I314 L315	I301-W311 HydrophobicContact CG2-CH2 3.78Å; I301-W311 HydrophobicContact CG2-CZ3 4.42Å; Y305-W311 HydrophobicContact CD1-CZ2 4.39Å; Y305-W311 HydrophobicContact CD2-CH2 4.46Å; Y305-W311 HydrophobicContact CD2-CZ2 4.25Å; Y305-W311 HydrophobicContact CG-CH2 4.47Å; Y305-W311 AromaticContact CG-CZ2 3.9Å; Y305-W311 HydrophobicContact CG-CZ2 3.9Å; D309-W311 PolarHBondContact O-N 2.87Å; W311-W313 PolarHBondContact O-N 3.45Å; W311-W313 VanDerWaalsContact O-N 3.16Å; W311-I314 PolarHBondContact O-N 3.25Å; W311-L315 HydrophobicContact CZ3-CD2 4.27Å
312	I	85.9	Confident	87.3	Confident	1 Å²	1	54.8 Å²	54.8	1%	0.005	25%	0.253	C	S	.	.	H	α-helix	trans	-63.7	-25	-175.4	-155.9	63.7	0	0	0	113.2	W302 Y305 E308 I314 L315 Q316	W302-I312 HydrophobicContact CG-CD1 4.49Å; Y305-I312 WeakPolarHBondContact O-CG1 3.41Å; E308-I312 WeakPolarHBondContact O-CB 3.25Å; E308-I312 WeakPolarHBondContact O-CG2 3.41Å; E308-I312 PolarHBondContact O-N 3.16Å; I312-I314 PolarHBondContact O-N 3.39Å; I312-L315 HydrophobicContact CD1-CB 4.44Å; I312-L315 HydrophobicContact CD1-CD2 4.19Å; I312-L315 PolarHBondContact O-N 3.39Å; I312-L315 VanDerWaalsContact O-N 3.09Å; I312-Q316 PolarHBondContact O-N 3.34Å
313	W	85.6	Confident	87.3	Confident	49 Å²	49	56.6 Å²	56.6	19%	0.186	26%	0.261	C	S	.	.	H	α-helix	trans	-59.2	-32.6	178.2	66.6	-92.2	0	0	0	112.5	R310 W311 N317 R405 P407 F421	R310-W313 PolarHBondContact O-NE1 3.43Å; R310-W313 VanDerWaalsContact O-NE1 3.1Å; W311-W313 PolarHBondContact O-N 3.45Å; W311-W313 VanDerWaalsContact O-N 3.16Å; W313-N317 WeakPolarHBondContact O-CB 3.24Å; W313-N317 PolarHBondContact O-N 3.24Å; W313-N317 PolarHBondContact O-ND2 3.27Å; W313-R405 HydrophobicContact CB-CB 4.46Å; W313-P407 HydrophobicContact CD2-CG 4.32Å; W313-P407 HydrophobicContact CH2-CG 4.31Å; W313-P407 HydrophobicContact CZ2-CG 3.94Å; W313-F421 HydrophobicContact CB-CE1 3.88Å; W313-F421 HydrophobicContact CG-CE1 4.02Å
314	I	90.4	Very high	87.6	Confident	99 Å²	99	56.1 Å²	56.1	51%	0.508	26%	0.256	S	S	.	.	H	α-helix	trans	-65.5	-47.7	176.2	-58.8	176.2	0	0	0	109.4	W311 I312 N317 L318	W311-I314 PolarHBondContact O-N 3.25Å; I312-I314 PolarHBondContact O-N 3.39Å; I314-N317 PolarHBondContact O-N 3.24Å; I314-L318 WeakPolarHBondContact O-CB 3.39Å; I314-L318 PolarHBondContact O-N 2.99Å
315	L	90.9	Very high	87.7	Confident	26 Å²	26	52 Å²	52	14%	0.136	23%	0.23	C	C	.	.	H	α-helix	trans	-66.5	-40.5	-179.2	-161.7	60.7	0	0	0	111.2	V298 I301 W302 W311 I312 L318 L319	V298-L315 HydrophobicContact CG1-CD1 3.61Å; V298-L315 HydrophobicContact CG1-CG 4.35Å; I301-L315 HydrophobicContact CB-CD2 4.48Å; I301-L315 HydrophobicContact CG2-CD2 3.96Å; W302-L315 HydrophobicContact CB-CD2 3.6Å; W302-L315 HydrophobicContact CB-CG 4.03Å; W302-L315 HydrophobicContact CG-CD2 4.4Å; W302-L315 HydrophobicContact CG-CG 4.5Å; W311-L315 HydrophobicContact CZ3-CD2 4.27Å; I312-L315 HydrophobicContact CD1-CB 4.44Å; I312-L315 HydrophobicContact CD1-CD2 4.19Å; I312-L315 PolarHBondContact O-N 3.39Å; I312-L315 VanDerWaalsContact O-N 3.09Å; L315-L318 HydrophobicContact CD1-CD2 4.49Å; L315-L318 PolarHBondContact O-N 3.2Å; L315-L319 HydrophobicContact CG-CD1 4.45Å; L315-L319 WeakPolarHBondContact O-CB 3.5Å; L315-L319 WeakPolarHBondContact O-CG 3.31Å; L315-L319 PolarHBondContact O-N 3.31Å
316	Q	91.1	Very high	87.9	Confident	3 Å²	3	47.4 Å²	47.4	1%	0.014	22%	0.215	C	C	.	.	H	α-helix	trans	-59.8	-46	173.3	-175.3	168.9	-23.2	0	0	111.9	I312 L319 G320 V403 Y426	I312-Q316 PolarHBondContact O-N 3.34Å; Q316-L319 PolarHBondContact O-N 3.42Å; Q316-G320 PolarHBondContact O-N 3.42Å; Q316-V403 PolarHBondContact NE2-O 3.39Å; Q316-Y426 PolarHBondContact O-OH 3.33Å
317	N	93.1	Very high	88.3	Confident	8 Å²	8	47.1 Å²	47.1	4%	0.043	22%	0.215	C	C	.	.	H	α-helix	trans	-66.2	-39.9	178.2	-72.3	-22.9	0	0	0	111.7	W313 I314 G320 I321 M404 R405	W313-N317 WeakPolarHBondContact O-CB 3.24Å; W313-N317 PolarHBondContact O-N 3.24Å; W313-N317 PolarHBondContact O-ND2 3.27Å; I314-N317 PolarHBondContact O-N 3.24Å; N317-G320 PolarHBondContact O-N 2.97Å; N317-I321 WeakPolarHBondContact O-CB 3.36Å; N317-I321 WeakPolarHBondContact O-CG1 3.48Å; N317-I321 PolarHBondContact O-N 3.04Å; N317-M404 WeakPolarHBondContact OD1-CA 3.5Å; N317-R405 PolarHBondContact ND2-O 3.44Å; N317-R405 PolarHBondContact OD1-N 2.96Å; N317-R405 PolarHBondContact OD1-O 2.86Å
318	L	93.9	Very high	88.9	Confident	88 Å²	88	44 Å²	44	46%	0.461	20%	0.199	S	C	.	.	H	α-helix	trans	-61.1	-49.4	176	180	65.1	0	0	0	111.6	I314 L315 G320 I321 A322	I314-L318 WeakPolarHBondContact O-CB 3.39Å; I314-L318 PolarHBondContact O-N 2.99Å; L315-L318 HydrophobicContact CD1-CD2 4.49Å; L315-L318 PolarHBondContact O-N 3.2Å; L318-G320 VanDerWaalsContact C-N 3.32Å; L318-G320 PolarHBondContact O-N 3.31Å; L318-I321 PolarHBondContact O-N 2.92Å; L318-A322 PolarHBondContact O-N 3.49Å
319	L	94.4	Very high	89.2	Confident	0 Å²	0	41.9 Å²	41.9	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-62.9	-39.9	176.2	-70.1	173.7	0	0	0	111.6	F251 T255 L259 V298 W302 L315 Q316 A322 F323	F251-L319 HydrophobicContact CZ-CB 4.41Å; T255-L319 HydrophobicContact CG2-CB 4.08Å; L259-L319 HydrophobicContact CD2-CD2 4.02Å; V298-L319 HydrophobicContact CG1-CD2 4.14Å; W302-L319 HydrophobicContact CB-CD1 3.58Å; W302-L319 HydrophobicContact CD2-CD1 4.06Å; W302-L319 HydrophobicContact CG-CD1 3.57Å; L315-L319 HydrophobicContact CG-CD1 4.45Å; L315-L319 WeakPolarHBondContact O-CB 3.5Å; L315-L319 WeakPolarHBondContact O-CG 3.31Å; L315-L319 PolarHBondContact O-N 3.31Å; Q316-L319 PolarHBondContact O-N 3.42Å; L319-A322 PolarHBondContact O-N 3.03Å; L319-F323 VanDerWaalsContact O-CB 3.28Å; L319-F323 WeakPolarHBondContact O-CB 3.26Å; L319-F323 PolarHBondContact O-N 2.93Å
320	G	93.8	Very high	89.8	Confident	0 Å²	0	42 Å²	42	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-62.9	-44.2	175.6	0	0	0	0	0	113.2	Q316 N317 L318 F323 C324 Y426	Q316-G320 PolarHBondContact O-N 3.42Å; N317-G320 PolarHBondContact O-N 2.97Å; L318-G320 VanDerWaalsContact C-N 3.32Å; L318-G320 PolarHBondContact O-N 3.31Å; G320-F323 PolarHBondContact O-N 3.43Å; G320-C324 WeakPolarHBondContact O-CB 3.37Å; G320-C324 PolarHBondContact O-N 3.26Å; G320-C324 PolarHBondContact O-SG 3.32Å; G320-Y426 WeakPolarHBondContact CA-OH 3.18Å
321	I	94.9	Very high	90.3	Very high	45 Å²	45	32.7 Å²	32.7	23%	0.231	16%	0.156	C	C	.	.	H	α-helix	trans	-61.3	-49.5	175	-68.6	163	0	0	0	109.8	I176 T180 N317 L318 F323 C324 L325 M404	I176-I321 HydrophobicContact CG2-CD1 3.96Å; I176-I321 HydrophobicContact CG2-CG1 4.18Å; T180-I321 HydrophobicContact CG2-CG2 4.4Å; N317-I321 WeakPolarHBondContact O-CB 3.36Å; N317-I321 WeakPolarHBondContact O-CG1 3.48Å; N317-I321 PolarHBondContact O-N 3.04Å; L318-I321 PolarHBondContact O-N 2.92Å; I321-F323 VanDerWaalsContact C-N 3.31Å; I321-F323 PolarHBondContact O-N 3.42Å; I321-C324 PolarHBondContact O-N 2.89Å; I321-L325 HydrophobicContact CG2-CD1 3.88Å; I321-L325 HydrophobicContact CG2-CG 4.24Å; I321-L325 WeakPolarHBondContact O-CB 3.28Å; I321-L325 VanDerWaalsContact O-CG 3.26Å; I321-L325 WeakPolarHBondContact O-CG 3.42Å; I321-L325 PolarHBondContact O-N 2.9Å; I321-M404 HydrophobicContact CG1-CE 3.82Å
322	A	94.9	Very high	90.1	Very high	3 Å²	3	28.2 Å²	28.2	3%	0.025	14%	0.14	C	C	.	.	H	α-helix	trans	-57.9	-45	177.9	0	0	0	0	0	111.5	A258 L259 L318 L319 L325 N326	A258-A322 HydrophobicContact CB-CB 4.49Å; L259-A322 HydrophobicContact CB-CB 4.29Å; L259-A322 HydrophobicContact CD1-CB 4.12Å; L318-A322 PolarHBondContact O-N 3.49Å; L319-A322 PolarHBondContact O-N 3.03Å; A322-L325 PolarHBondContact O-N 3.41Å; A322-N326 WeakPolarHBondContact O-CB 3.29Å; A322-N326 PolarHBondContact O-N 3.27Å
323	F	94.6	Very high	89.9	Confident	44 Å²	44	28.3 Å²	28.3	19%	0.193	14%	0.141	C	C	.	.	H	α-helix	trans	-58.2	-52.3	175.3	175.4	-104.5	0	0	0	112.1	A254 T255 L319 G320 I321 L325 N326 F327 Y426 I430	A254-F323 HydrophobicContact CB-CD2 4.12Å; A254-F323 HydrophobicContact CB-CE2 4Å; T255-F323 HydrophobicContact CG2-CB 3.97Å; T255-F323 HydrophobicContact CG2-CG 4.45Å; L319-F323 VanDerWaalsContact O-CB 3.28Å; L319-F323 WeakPolarHBondContact O-CB 3.26Å; L319-F323 PolarHBondContact O-N 2.93Å; G320-F323 PolarHBondContact O-N 3.43Å; I321-F323 VanDerWaalsContact C-N 3.31Å; I321-F323 PolarHBondContact O-N 3.42Å; F323-L325 PolarHBondContact O-N 3.26Å; F323-N326 PolarHBondContact O-N 3.14Å; F323-F327 HydrophobicContact CE2-CD2 4.46Å; F323-F327 HydrophobicContact CZ-CD2 4.1Å; F323-F327 VanDerWaalsContact O-CB 3.28Å; F323-F327 WeakPolarHBondContact O-CB 3.47Å; F323-F327 PolarHBondContact O-N 2.94Å; F323-Y426 HydrophobicContact CD1-CD2 4.19Å; F323-Y426 HydrophobicContact CE1-CD2 4.42Å; F323-I430 HydrophobicContact CD1-CD1 4.06Å; F323-I430 HydrophobicContact CE1-CD1 3.63Å
324	C	95.1	Very high	89.5	Confident	0 Å²	0	26.4 Å²	26.4	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-59	-44.6	178.8	-71	0	0	0	0	112.4	T180 G320 I321 F327 M328 I429 I430	T180-C324 HydrophobicContact CG2-CB 3.68Å; G320-C324 WeakPolarHBondContact O-CB 3.37Å; G320-C324 PolarHBondContact O-N 3.26Å; G320-C324 PolarHBondContact O-SG 3.32Å; I321-C324 PolarHBondContact O-N 2.89Å; C324-F327 PolarHBondContact O-N 3.2Å; C324-M328 HydrophobicContact CB-CE 4.32Å; C324-M328 VanDerWaalsContact O-CE 3.3Å; C324-M328 WeakPolarHBondContact O-CE 3.48Å; C324-M328 WeakPolarHBondContact O-CG 3.31Å; C324-M328 PolarHBondContact O-N 3.11Å; C324-I429 HydrophobicContact CB-CG2 4.39Å; C324-I430 HydrophobicContact CB-CD1 4.48Å; C324-I430 HydrophobicContact CB-CG1 4.08Å
325	L	93.4	Very high	89.3	Confident	10 Å²	10	23.4 Å²	23.4	5%	0.052	12%	0.12	C	C	.	.	H	α-helix	trans	-62.3	-48.4	177.7	-68.8	176.6	0	0	0	111.7	T180 L183 W187 I321 A322 F323 F327 M328 K329	T180-L325 HydrophobicContact CG2-CD2 4.29Å; T180-L325 HydrophobicContact CG2-CG 4.43Å; T180-L325 WeakPolarHBondContact O-CD2 3.43Å; L183-L325 HydrophobicContact CB-CD2 3.78Å; W187-L325 HydrophobicContact CE3-CB 3.96Å; W187-L325 HydrophobicContact CE3-CD1 4.35Å; W187-L325 HydrophobicContact CZ3-CB 3.76Å; W187-L325 HydrophobicContact CZ3-CD1 4.15Å; I321-L325 HydrophobicContact CG2-CD1 3.88Å; I321-L325 HydrophobicContact CG2-CG 4.24Å; I321-L325 WeakPolarHBondContact O-CB 3.28Å; I321-L325 VanDerWaalsContact O-CG 3.26Å; I321-L325 WeakPolarHBondContact O-CG 3.42Å; I321-L325 PolarHBondContact O-N 2.9Å; A322-L325 PolarHBondContact O-N 3.41Å; F323-L325 PolarHBondContact O-N 3.26Å; L325-F327 VanDerWaalsContact C-N 3.29Å; L325-F327 PolarHBondContact O-N 3.22Å; L325-M328 HydrophobicContact CD2-CE 4.37Å; L325-M328 PolarHBondContact O-N 3.2Å; L325-K329 WeakPolarHBondContact O-CB 3.3Å; L325-K329 PolarHBondContact O-N 3.23Å
326	N	91.1	Very high	89.2	Confident	27 Å²	27	22.3 Å²	22.3	14%	0.144	11%	0.114	C	C	.	.	H	α-helix	trans	-65.2	-35.3	179.5	-169.7	56.8	0	0	0	111.9	A258 A322 F323 K329 T330	A258-N326 HydrophobicContact CB-CB 3.53Å; A322-N326 WeakPolarHBondContact O-CB 3.29Å; A322-N326 PolarHBondContact O-N 3.27Å; F323-N326 PolarHBondContact O-N 3.14Å; N326-K329 PolarHBondContact O-N 3.31Å; N326-T330 VanDerWaalsContact O-CB 3.31Å; N326-T330 WeakPolarHBondContact O-CB 3.29Å; N326-T330 PolarHBondContact O-N 3.4Å; N326-T330 PolarHBondContact O-OG1 3.3Å
327	F	90.4	Very high	89.1	Confident	51 Å²	51	27.4 Å²	27.4	22%	0.224	14%	0.136	C	C	.	.	H	α-helix	trans	-65.8	-47.2	176.8	-164.6	-83.3	0	0	0	111.7	F323 C324 L325 K329 T330 I331 I430 L434	F323-F327 HydrophobicContact CE2-CD2 4.46Å; F323-F327 HydrophobicContact CZ-CD2 4.1Å; F323-F327 VanDerWaalsContact O-CB 3.28Å; F323-F327 WeakPolarHBondContact O-CB 3.47Å; F323-F327 PolarHBondContact O-N 2.94Å; C324-F327 PolarHBondContact O-N 3.2Å; L325-F327 VanDerWaalsContact C-N 3.29Å; L325-F327 PolarHBondContact O-N 3.22Å; F327-K329 VanDerWaalsContact C-N 3.28Å; F327-K329 PolarHBondContact O-N 3.02Å; F327-T330 PolarHBondContact O-N 3.34Å; F327-I331 HydrophobicContact CD1-CD1 3.86Å; F327-I331 HydrophobicContact CD1-CG1 4.19Å; F327-I331 HydrophobicContact CD2-CD1 4.43Å; F327-I331 HydrophobicContact CE1-CD1 3.21Å; F327-I331 HydrophobicContact CE1-CG1 4.03Å; F327-I331 HydrophobicContact CE2-CD1 3.84Å; F327-I331 HydrophobicContact CG-CD1 4.46Å; F327-I331 HydrophobicContact CZ-CD1 3.19Å; F327-I331 HydrophobicContact CZ-CG1 4.27Å; F327-I331 PolarHBondContact O-N 3.48Å; F327-I430 HydrophobicContact CB-CD1 4.24Å; F327-I430 HydrophobicContact CD1-CB 4.39Å; F327-I430 HydrophobicContact CD1-CD1 4.25Å; F327-I430 HydrophobicContact CD1-CG1 4.38Å; F327-I430 HydrophobicContact CD1-CG2 3.18Å; F327-I430 HydrophobicContact CE1-CG2 3.19Å; F327-I430 HydrophobicContact CG-CD1 4.14Å; F327-I430 HydrophobicContact CG-CG2 4.12Å; F327-I430 HydrophobicContact CZ-CG2 4.17Å; F327-L434 HydrophobicContact CD1-CD2 4.48Å; F327-L434 HydrophobicContact CE1-CD1 4.34Å
328	M	90.4	Very high	88.9	Confident	0 Å²	0	27.3 Å²	27.3	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-64	-31.4	175	-73.6	-177.1	-81.7	0	0	113.1	T180 C324 L325	T180-M328 HydrophobicContact CG2-CE 4.17Å; T180-M328 WeakPolarHBondContact O-CE 3.38Å; C324-M328 HydrophobicContact CB-CE 4.32Å; C324-M328 VanDerWaalsContact O-CE 3.3Å; C324-M328 WeakPolarHBondContact O-CE 3.48Å; C324-M328 WeakPolarHBondContact O-CG 3.31Å; C324-M328 PolarHBondContact O-N 3.11Å; L325-M328 HydrophobicContact CD2-CE 4.37Å; L325-M328 PolarHBondContact O-N 3.2Å
329	K	85.6	Confident	88.7	Confident	61 Å²	61	23.1 Å²	23.1	27%	0.265	11%	0.114	S	C	.	.	H	α-helix	trans	-67.9	-46.3	172.8	175.2	-171.1	173	-174.6	0	111.8	W187 L325 N326 F327	W187-K329 HydrophobicContact CZ2-CD 4.13Å; L325-K329 WeakPolarHBondContact O-CB 3.3Å; L325-K329 PolarHBondContact O-N 3.23Å; N326-K329 PolarHBondContact O-N 3.31Å; F327-K329 VanDerWaalsContact C-N 3.28Å; F327-K329 PolarHBondContact O-N 3.02Å
330	T	82.6	Confident	88.6	Confident	48 Å²	48	24.8 Å²	24.8	29%	0.294	12%	0.124	S	C	.	.	H	α-helix	trans	-78.6	-40.7	-170.2	-55.5	0	0	0	0	112.2	N326 F327 T332	N326-T330 VanDerWaalsContact O-CB 3.31Å; N326-T330 WeakPolarHBondContact O-CB 3.29Å; N326-T330 PolarHBondContact O-N 3.4Å; N326-T330 PolarHBondContact O-OG1 3.3Å; F327-T330 PolarHBondContact O-N 3.34Å; T330-T332 PolarHBondContact O-N 3.25Å
331	I	82.3	Confident	88.5	Confident	13 Å²	13	27.3 Å²	27.3	7%	0.067	14%	0.137	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-82.4	117.6	179.8	-61.6	-161.2	0	0	0	109.8	Y217 F327 L333 L434	Y217-I331 HydrophobicContact CD2-CG2 3.73Å; Y217-I331 HydrophobicContact CE2-CB 4.25Å; Y217-I331 HydrophobicContact CE2-CD1 3.65Å; Y217-I331 HydrophobicContact CE2-CG1 3.86Å; Y217-I331 HydrophobicContact CE2-CG2 3.65Å; Y217-I331 WeakPolarHBondContact OH-CD1 3.07Å; F327-I331 HydrophobicContact CD1-CD1 3.86Å; F327-I331 HydrophobicContact CD1-CG1 4.19Å; F327-I331 HydrophobicContact CD2-CD1 4.43Å; F327-I331 HydrophobicContact CE1-CD1 3.21Å; F327-I331 HydrophobicContact CE1-CG1 4.03Å; F327-I331 HydrophobicContact CE2-CD1 3.84Å; F327-I331 HydrophobicContact CG-CD1 4.46Å; F327-I331 HydrophobicContact CZ-CD1 3.19Å; F327-I331 HydrophobicContact CZ-CG1 4.27Å; F327-I331 PolarHBondContact O-N 3.48Å; I331-L333 HydrophobicContact CG2-CD2 4.43Å; I331-L434 HydrophobicContact CB-CD2 3.73Å; I331-L434 HydrophobicContact CG2-CD1 4.06Å; I331-L434 HydrophobicContact CG2-CD2 3.73Å
332	T	77.2	Confident	88.2	Confident	16 Å²	16	25.6 Å²	25.6	10%	0.098	13%	0.128	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-112.3	113.7	177.4	63.2	0	0	0	0	111.1	T330 R441	T330-T332 PolarHBondContact O-N 3.25Å; T332-R441 VanDerWaalsContact CA-NH1 3.33Å
333	L	82.4	Confident	88.1	Confident	3 Å²	3	25.4 Å²	25.4	2%	0.016	13%	0.127	C	C	.	.			trans	-83.6	127	168.6	-56.3	179.9	0	0	0	108.2	I331 I338 C339 L342 L434 Y438	I331-L333 HydrophobicContact CG2-CD2 4.43Å; L333-I338 HydrophobicContact CD2-CG2 3.98Å; L333-C339 HydrophobicContact CD1-CB 4.3Å; L333-C339 WeakPolarHBondContact CD1-SG 3.21Å; L333-L342 HydrophobicContact CD1-CD2 4.33Å; L333-L342 HydrophobicContact CD2-CD2 4.31Å; L333-L434 HydrophobicContact CD1-CB 3.86Å; L333-Y438 WeakPolarHBondContact O-CD2 3.49Å
334	S	77.2	Confident	88	Confident	10 Å²	10	26 Å²	26	7%	0.07	14%	0.136	C	C	.	.			trans	-83	-31	-178.6	43.7	0	0	0	0	113.2	I338 Y438 E513	S334-I338 VanDerWaalsContact OG-CD1 3.28Å; S334-I338 WeakPolarHBondContact OG-CD1 3.46Å; S334-Y438 WeakPolarHBondContact O-CE2 3.19Å; S334-E513 WeakPolarHBondContact CB-OE2 3.19Å
335	N	85	Confident	87.9	Confident	35 Å²	35	28.7 Å²	28.7	19%	0.187	15%	0.15	C	C	.	.			trans	-136.8	149.1	-170	-58.1	-47.3	0	0	0	112.2	K337 I338 C339 T508 G509	N335-K337 VanDerWaalsContact C-N 3.29Å; N335-K337 PolarHBondContact O-N 3.03Å; N335-I338 HydrophobicContact CB-CD1 4.07Å; N335-I338 HydrophobicContact CB-CG1 4.09Å; N335-I338 WeakPolarHBondContact O-CB 3.03Å; N335-I338 PolarHBondContact O-N 2.96Å; N335-C339 PolarHBondContact O-N 3.44Å; N335-C339 PolarHBondContact O-SG 2.94Å; N335-T508 PolarHBondContact OD1-O 2.98Å; N335-G509 WeakPolarHBondContact OD1-CA 3.01Å; N335-G509 PolarHBondContact OD1-N 3.38Å
336	F	90.1	Very high	87.7	Confident	4 Å²	4	28.9 Å²	28.9	2%	0.018	15%	0.151	C	C	.	.	H	α-helix	trans	-64.7	-33.9	173.3	-175.6	-115.5	0	0	0	112	I338 C339 V340 L435 Y438 L490 A494 F506 W507	F336-I338 PolarHBondContact O-N 3.41Å; F336-C339 HydrophobicContact CD2-CB 4.19Å; F336-C339 WeakPolarHBondContact O-CA 3.17Å; F336-C339 VanDerWaalsContact O-CB 3.26Å; F336-C339 WeakPolarHBondContact O-CB 3.42Å; F336-C339 PolarHBondContact O-N 2.9Å; F336-V340 HydrophobicContact CD1-CG2 3.93Å; F336-V340 HydrophobicContact CE1-CG2 3.62Å; F336-V340 HydrophobicContact CE2-CG2 4.38Å; F336-V340 HydrophobicContact CG-CG2 4.44Å; F336-V340 HydrophobicContact CZ-CG2 3.87Å; F336-V340 WeakPolarHBondContact O-CG2 3.42Å; F336-V340 PolarHBondContact O-N 3.49Å; F336-L435 HydrophobicContact CD2-CD1 3.9Å; F336-L435 HydrophobicContact CE2-CD1 3.77Å; F336-Y438 HydrophobicContact CB-CE1 3.77Å; F336-Y438 HydrophobicContact CD2-CE1 4.29Å; F336-Y438 PolarHBondContact N-OH 2.63Å; F336-L490 HydrophobicContact CE2-CD2 3.92Å; F336-L490 HydrophobicContact CZ-CD2 4.03Å; F336-A494 HydrophobicContact CE1-CB 4.31Å; F336-A494 HydrophobicContact CZ-CB 4.25Å; F336-F506 HydrophobicContact CB-CD1 3.89Å; F336-F506 HydrophobicContact CB-CE1 3.94Å; F336-F506 HydrophobicContact CB-CG 4.36Å; F336-F506 HydrophobicContact CB-CZ 4.42Å; F336-F506 WeakPolarHBondContact CB-O 3.34Å; F336-F506 AromaticContact CD1-CD1 3.74Å; F336-F506 HydrophobicContact CD1-CD1 3.74Å; F336-F506 AromaticContact CD1-CE1 3.69Å; F336-F506 HydrophobicContact CD1-CE1 3.69Å; F336-F506 HydrophobicContact CD2-CD1 4.02Å; F336-F506 AromaticContact CD2-CE1 3.23Å; F336-F506 HydrophobicContact CD2-CE1 3.23Å; F336-F506 AromaticContact CD2-CZ 3.61Å; F336-F506 HydrophobicContact CD2-CZ 3.61Å; F336-F506 HydrophobicContact CE1-CD1 4.24Å; F336-F506 AromaticContact CE1-CE1 3.93Å; F336-F506 HydrophobicContact CE1-CE1 3.93Å; F336-F506 HydrophobicContact CE2-CD1 4.49Å; F336-F506 AromaticContact CE2-CE1 3.5Å; F336-F506 HydrophobicContact CE2-CE1 3.5Å; F336-F506 HydrophobicContact CE2-CZ 4.01Å; F336-F506 AromaticContact CG-CD1 3.62Å; F336-F506 HydrophobicContact CG-CD1 3.62Å; F336-F506 AromaticContact CG-CE1 3.33Å; F336-F506 HydrophobicContact CG-CE1 3.33Å; F336-F506 HydrophobicContact CG-CZ 4.04Å; F336-F506 AromaticContact CZ-CE1 3.84Å; F336-F506 HydrophobicContact CZ-CE1 3.84Å; F336-F506 PolarHBondContact N-O 3.39Å; F336-W507 AromaticContact CD1-CE3 3.67Å; F336-W507 HydrophobicContact CD1-CE3 3.67Å; F336-W507 AromaticContact CD1-CZ3 3.94Å; F336-W507 HydrophobicContact CD1-CZ3 3.94Å; F336-W507 HydrophobicContact CE1-CE3 4.13Å; F336-W507 HydrophobicContact CE1-CZ3 4.03Å
337	K	89.3	Confident	87.8	Confident	109 Å²	109	29.6 Å²	29.6	47%	0.474	16%	0.155	S	C	.	.	H	α-helix	trans	-51.5	-42.2	172.8	-178.7	-176.8	177.2	-176.3	0	112.2	N335 V340 I341 W507	N335-K337 VanDerWaalsContact C-N 3.29Å; N335-K337 PolarHBondContact O-N 3.03Å; K337-V340 PolarHBondContact O-N 3.37Å; K337-I341 HydrophobicContact CG-CD1 4.02Å; K337-I341 WeakPolarHBondContact O-CG1 3.48Å; K337-I341 PolarHBondContact O-N 2.87Å; K337-W507 HydrophobicContact CB-CZ2 4.4Å; K337-W507 HydrophobicContact CG-CZ2 4.3Å; K337-W507 PolarHBondContact N-O 3.13Å
338	I	87.3	Confident	87.8	Confident	6 Å²	6	32.6 Å²	32.6	3%	0.031	17%	0.173	C	C	.	.	H	α-helix	trans	-67.5	-41	179.7	-63.6	176.6	0	0	0	110.1	P219 I222 L333 S334 N335 F336 I341 L342	P219-I338 HydrophobicContact CG-CG1 4.31Å; I222-I338 HydrophobicContact CD1-CB 4.45Å; I222-I338 HydrophobicContact CD1-CG2 3.07Å; L333-I338 HydrophobicContact CD2-CG2 3.98Å; S334-I338 VanDerWaalsContact OG-CD1 3.28Å; S334-I338 WeakPolarHBondContact OG-CD1 3.46Å; N335-I338 HydrophobicContact CB-CD1 4.07Å; N335-I338 HydrophobicContact CB-CG1 4.09Å; N335-I338 WeakPolarHBondContact O-CB 3.03Å; N335-I338 PolarHBondContact O-N 2.96Å; F336-I338 PolarHBondContact O-N 3.41Å; I338-I341 PolarHBondContact O-N 2.69Å; I338-L342 WeakPolarHBondContact O-CB 2.9Å; I338-L342 PolarHBondContact O-N 3.29Å
339	C	90.4	Very high	87.7	Confident	0 Å²	0	34.9 Å²	34.9	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-59.3	-47.8	173.7	-54.9	0	0	0	0	111.4	L333 N335 F336 I341 L342 L343 L435	L333-C339 HydrophobicContact CD1-CB 4.3Å; L333-C339 WeakPolarHBondContact CD1-SG 3.21Å; N335-C339 PolarHBondContact O-N 3.44Å; N335-C339 PolarHBondContact O-SG 2.94Å; F336-C339 HydrophobicContact CD2-CB 4.19Å; F336-C339 WeakPolarHBondContact O-CA 3.17Å; F336-C339 VanDerWaalsContact O-CB 3.26Å; F336-C339 WeakPolarHBondContact O-CB 3.42Å; F336-C339 PolarHBondContact O-N 2.9Å; C339-I341 PolarHBondContact O-N 3.02Å; C339-L342 PolarHBondContact O-N 3.41Å; C339-L343 HydrophobicContact CB-CD1 4.48Å; C339-L343 WeakPolarHBondContact O-CB 3.18Å; C339-L343 WeakPolarHBondContact O-CD1 3.45Å; C339-L343 PolarHBondContact O-N 3.1Å; C339-L435 HydrophobicContact CB-CD1 3.93Å
340	V	92.8	Very high	87.8	Confident	35 Å²	35	32.2 Å²	32.2	21%	0.212	17%	0.17	C	C	.	.	H	α-helix	trans	-58.5	-49.7	178.2	-178.2	0	0	0	0	110.6	F336 K337 L342 S344 L490 W507	F336-V340 HydrophobicContact CD1-CG2 3.93Å; F336-V340 HydrophobicContact CE1-CG2 3.62Å; F336-V340 HydrophobicContact CE2-CG2 4.38Å; F336-V340 HydrophobicContact CG-CG2 4.44Å; F336-V340 HydrophobicContact CZ-CG2 3.87Å; F336-V340 WeakPolarHBondContact O-CG2 3.42Å; F336-V340 PolarHBondContact O-N 3.49Å; K337-V340 PolarHBondContact O-N 3.37Å; V340-L342 PolarHBondContact O-N 3.29Å; V340-S344 WeakPolarHBondContact O-CB 3.36Å; V340-S344 PolarHBondContact O-N 3.43Å; V340-S344 PolarHBondContact O-OG 2.94Å; V340-L490 HydrophobicContact CG2-CD2 4.15Å; V340-W507 HydrophobicContact CG2-CH2 4.27Å; V340-W507 HydrophobicContact CG2-CZ3 4.04Å
341	I	91.1	Very high	88.2	Confident	53 Å²	53	31.8 Å²	31.8	27%	0.272	17%	0.167	S	C	.	.	H	α-helix	trans	-60.4	-49.5	-179.5	-67.1	166.5	0	0	0	111	K337 I338 C339 L345	K337-I341 HydrophobicContact CG-CD1 4.02Å; K337-I341 WeakPolarHBondContact O-CG1 3.48Å; K337-I341 PolarHBondContact O-N 2.87Å; I338-I341 PolarHBondContact O-N 2.69Å; C339-I341 PolarHBondContact O-N 3.02Å; I341-L345 HydrophobicContact CG2-CD1 3.84Å; I341-L345 HydrophobicContact CG2-CG 4.47Å; I341-L345 WeakPolarHBondContact O-CB 3.25Å; I341-L345 VanDerWaalsContact O-CG 3.25Å; I341-L345 WeakPolarHBondContact O-CG 3.42Å; I341-L345 PolarHBondContact O-N 2.91Å
342	L	89.9	Confident	88.5	Confident	9 Å²	9	35.2 Å²	35.2	5%	0.047	18%	0.182	C	C	.	.	H	α-helix	trans	-60.5	-52.6	-179.2	175.9	65.7	0	0	0	111.8	I222 L333 I338 C339 V340 L345 L346 L434	I222-L342 HydrophobicContact CD1-CB 4.33Å; I222-L342 HydrophobicContact CG1-CD1 4.33Å; I222-L342 HydrophobicContact CG2-CB 3.98Å; I222-L342 HydrophobicContact CG2-CD1 3.58Å; I222-L342 HydrophobicContact CG2-CG 4.38Å; L333-L342 HydrophobicContact CD1-CD2 4.33Å; L333-L342 HydrophobicContact CD2-CD2 4.31Å; I338-L342 WeakPolarHBondContact O-CB 2.9Å; I338-L342 PolarHBondContact O-N 3.29Å; C339-L342 PolarHBondContact O-N 3.41Å; V340-L342 PolarHBondContact O-N 3.29Å; L342-L345 PolarHBondContact O-N 2.95Å; L342-L346 HydrophobicContact CD1-CD1 3.73Å; L342-L346 HydrophobicContact CD1-CG 4.32Å; L342-L346 HydrophobicContact CG-CD1 3.99Å; L342-L346 WeakPolarHBondContact O-CB 3.34Å; L342-L346 WeakPolarHBondContact O-CG 3.38Å; L342-L346 PolarHBondContact O-N 3.35Å; L342-L434 HydrophobicContact CD2-CD1 4.07Å
343	L	92.2	Very high	88.9	Confident	0 Å²	0	34.8 Å²	34.8	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-67.9	-37.7	-176.1	-85.6	76.1	0	0	0	111.6	C339 L346 L347 V431 L435 V486 L490	C339-L343 HydrophobicContact CB-CD1 4.48Å; C339-L343 WeakPolarHBondContact O-CB 3.18Å; C339-L343 WeakPolarHBondContact O-CD1 3.45Å; C339-L343 PolarHBondContact O-N 3.1Å; L343-L346 PolarHBondContact O-N 3.46Å; L343-L347 VanDerWaalsContact O-CB 3.31Å; L343-L347 WeakPolarHBondContact O-CB 3.31Å; L343-L347 PolarHBondContact O-N 3.37Å; L343-V431 HydrophobicContact CD1-CG1 4.44Å; L343-V431 HydrophobicContact CG-CG1 4.06Å; L343-L435 HydrophobicContact CD2-CB 4.29Å; L343-L435 HydrophobicContact CD2-CD2 3.95Å; L343-V486 HydrophobicContact CB-CG1 3.87Å; L343-V486 HydrophobicContact CB-CG2 4.21Å; L343-V486 HydrophobicContact CD2-CG1 4.43Å; L343-V486 HydrophobicContact CD2-CG2 4.35Å; L343-V486 HydrophobicContact CG-CG2 4.42Å; L343-L490 HydrophobicContact CB-CD1 4Å; L343-L490 HydrophobicContact CB-CG 4.44Å; L343-L490 HydrophobicContact CD2-CD1 4.41Å; L343-L490 HydrophobicContact CD2-CD2 4.12Å; L343-L490 HydrophobicContact CD2-CG 3.98Å
344	S	92.8	Very high	89	Confident	55 Å²	55	35.7 Å²	35.7	39%	0.385	19%	0.185	S	C	.	.	H	α-helix	trans	-67.6	-38.9	175.8	-66	0	0	0	0	112.7	V340 L347 L348	V340-S344 WeakPolarHBondContact O-CB 3.36Å; V340-S344 PolarHBondContact O-N 3.43Å; V340-S344 PolarHBondContact O-OG 2.94Å; S344-L347 PolarHBondContact O-N 2.88Å; S344-L348 PolarHBondContact O-N 3.29Å
345	L	91.9	Very high	89.4	Confident	58 Å²	58	39.7 Å²	39.7	30%	0.304	20%	0.201	S	C	.	.	H	α-helix	trans	-65.9	-41.5	175	-74.7	173.5	0	0	0	111.8	I222 I223 V226 I341 L342 L348 Y349	I222-L345 HydrophobicContact CG2-CD1 4.43Å; I223-L345 HydrophobicContact CG1-CD1 4.23Å; V226-L345 HydrophobicContact CG2-CB 4.29Å; I341-L345 HydrophobicContact CG2-CD1 3.84Å; I341-L345 HydrophobicContact CG2-CG 4.47Å; I341-L345 WeakPolarHBondContact O-CB 3.25Å; I341-L345 VanDerWaalsContact O-CG 3.25Å; I341-L345 WeakPolarHBondContact O-CG 3.42Å; I341-L345 PolarHBondContact O-N 2.91Å; L342-L345 PolarHBondContact O-N 2.95Å; L345-L348 PolarHBondContact O-N 2.95Å; L345-Y349 WeakPolarHBondContact O-CB 3.42Å; L345-Y349 PolarHBondContact O-N 3.25Å
346	L	90.4	Very high	89.4	Confident	14 Å²	14	41.3 Å²	41.3	7%	0.073	21%	0.209	C	C	.	.	H	α-helix	trans	-70.2	-33.2	178.1	-70.9	171.7	0	0	0	112.7	V226 L342 L343 Y349 D350 V431 L482	V226-L346 HydrophobicContact CG2-CD2 4.12Å; V226-L346 HydrophobicContact CG2-CG 4.42Å; L342-L346 HydrophobicContact CD1-CD1 3.73Å; L342-L346 HydrophobicContact CD1-CG 4.32Å; L342-L346 HydrophobicContact CG-CD1 3.99Å; L342-L346 WeakPolarHBondContact O-CB 3.34Å; L342-L346 WeakPolarHBondContact O-CG 3.38Å; L342-L346 PolarHBondContact O-N 3.35Å; L343-L346 PolarHBondContact O-N 3.46Å; L346-Y349 WeakPolarHBondContact O-CB 3.49Å; L346-Y349 PolarHBondContact O-N 3.45Å; L346-D350 WeakPolarHBondContact O-CB 3.29Å; L346-D350 PolarHBondContact O-N 2.98Å; L346-V431 HydrophobicContact CB-CG1 4.39Å; L346-V431 HydrophobicContact CD1-CB 4.16Å; L346-V431 HydrophobicContact CD1-CG1 3.48Å; L346-V431 VanDerWaalsContact CD1-CG1 3.48Å; L346-V431 HydrophobicContact CD1-CG2 3.56Å; L346-L482 HydrophobicContact CB-CD1 4.19Å
347	L	92.1	Very high	89.2	Confident	41 Å²	41	41.2 Å²	41.2	22%	0.215	21%	0.209	C	C	.	.	H	α-helix	trans	-60.2	-48.9	169	169.6	62.6	0	0	0	111.4	L343 S344 Y349 D350 V351 L483 V486	L343-L347 VanDerWaalsContact O-CB 3.31Å; L343-L347 WeakPolarHBondContact O-CB 3.31Å; L343-L347 PolarHBondContact O-N 3.37Å; S344-L347 PolarHBondContact O-N 2.88Å; L347-Y349 VanDerWaalsContact C-N 3.28Å; L347-Y349 PolarHBondContact O-N 3.46Å; L347-D350 PolarHBondContact O-N 3.24Å; L347-V351 HydrophobicContact CD1-CG2 4.13Å; L347-V351 WeakPolarHBondContact O-CG2 3.41Å; L347-V351 PolarHBondContact O-N 2.91Å; L347-L483 VanDerWaalsContact CD1-CA 3.46Å; L347-L483 HydrophobicContact CD1-CB 4.34Å; L347-L483 HydrophobicContact CD1-CD1 3.99Å; L347-V486 HydrophobicContact CB-CB 4.45Å; L347-V486 HydrophobicContact CB-CG1 4.32Å; L347-V486 HydrophobicContact CB-CG2 4.35Å; L347-V486 HydrophobicContact CD2-CG1 4.22Å
348	L	91.3	Very high	88.9	Confident	115 Å²	115	37.6 Å²	37.6	60%	0.602	20%	0.196	S	C	*	.	H	α-helix	trans	-61.7	-40.6	178.6	-178.7	64	0	0	0	111.3	S344 L345 F352	S344-L348 PolarHBondContact O-N 3.29Å; L345-L348 PolarHBondContact O-N 2.95Å; L348-F352 VanDerWaalsContact O-CB 3.25Å; L348-F352 WeakPolarHBondContact O-CB 3.18Å; L348-F352 PolarHBondContact O-N 3.26Å
349	Y	87.8	Confident	88.8	Confident	47 Å²	47	45.8 Å²	45.8	18%	0.184	23%	0.232	C	C	.	.	H	α-helix	trans	-57	-50.3	173.6	160.8	-91.1	0	0	0	112.1	C230 L233 L345 L346 L347 F352 F353	C230-Y349 VanDerWaalsContact SG-CD2 3.54Å; L233-Y349 HydrophobicContact CD1-CE2 3.84Å; L233-Y349 WeakPolarHBondContact CD1-OH 3.36Å; L233-Y349 HydrophobicContact CG-CE2 4.46Å; L233-Y349 VanDerWaalsContact CG-OH 3.27Å; L233-Y349 WeakPolarHBondContact CG-OH 3.27Å; L345-Y349 WeakPolarHBondContact O-CB 3.42Å; L345-Y349 PolarHBondContact O-N 3.25Å; L346-Y349 WeakPolarHBondContact O-CB 3.49Å; L346-Y349 PolarHBondContact O-N 3.45Å; L347-Y349 VanDerWaalsContact C-N 3.28Å; L347-Y349 PolarHBondContact O-N 3.46Å; Y349-F352 PolarHBondContact O-N 2.85Å; Y349-F353 AromaticContact CD2-CD2 3.43Å; Y349-F353 HydrophobicContact CD2-CD2 3.43Å; Y349-F353 VanDerWaalsContact CD2-CD2 3.43Å; Y349-F353 AromaticContact CD2-CE2 3.5Å; Y349-F353 HydrophobicContact CD2-CE2 3.5Å; Y349-F353 VanDerWaalsContact CD2-CE2 3.5Å; Y349-F353 AromaticContact CE2-CD2 3.42Å; Y349-F353 HydrophobicContact CE2-CD2 3.42Å; Y349-F353 VanDerWaalsContact CE2-CD2 3.42Å; Y349-F353 AromaticContact CE2-CE2 3.41Å; Y349-F353 HydrophobicContact CE2-CE2 3.41Å; Y349-F353 VanDerWaalsContact CE2-CE2 3.41Å; Y349-F353 HydrophobicContact CE2-CG 4.4Å; Y349-F353 HydrophobicContact CE2-CZ 4.38Å; Y349-F353 HydrophobicContact CG-CD2 4.16Å; Y349-F353 WeakPolarHBondContact O-CD2 3.48Å; Y349-F353 PolarHBondContact O-N 3.11Å
350	D	88.8	Confident	88.3	Confident	5 Å²	5	53.5 Å²	53.5	3%	0.027	27%	0.266	C	S	.	.	H	α-helix	trans	-64.4	-44.8	-177	-160.1	28.5	0	0	0	110.8	L346 L347 F352 F353 V354 P480 L482	L346-D350 WeakPolarHBondContact O-CB 3.29Å; L346-D350 PolarHBondContact O-N 2.98Å; L347-D350 PolarHBondContact O-N 3.24Å; D350-F352 PolarHBondContact O-N 3.42Å; D350-F353 PolarHBondContact O-N 3.41Å; D350-V354 WeakPolarHBondContact O-CB 3.33Å; D350-V354 VanDerWaalsContact O-CG2 3.29Å; D350-V354 WeakPolarHBondContact O-CG2 3.49Å; D350-V354 PolarHBondContact O-N 2.96Å; D350-P480 HydrophobicContact CB-CB 4.19Å; D350-P480 VanDerWaalsContact OD2-CA 3.31Å; D350-P480 WeakPolarHBondContact OD2-CA 3.45Å; D350-P480 WeakPolarHBondContact OD2-CB 3.32Å; D350-L482 HydrophobicContact CB-CB 4.3Å; D350-L482 HydrophobicContact CB-CD1 4.29Å; D350-L482 WeakPolarHBondContact OD2-CB 3.39Å; D350-L482 PolarHBondContact OD2-N 2.7Å
351	V	89.1	Confident	87.6	Confident	39 Å²	39	52.4 Å²	52.4	24%	0.236	26%	0.259	C	S	.	.	H	α-helix	trans	-60.5	-44	175	170.6	0	0	0	0	111.6	L347 F355 L483	L347-V351 HydrophobicContact CD1-CG2 4.13Å; L347-V351 WeakPolarHBondContact O-CG2 3.41Å; L347-V351 PolarHBondContact O-N 2.91Å; V351-F355 HydrophobicContact CG1-CD2 4.06Å; V351-F355 WeakPolarHBondContact O-CB 3.34Å; V351-F355 PolarHBondContact O-N 2.92Å; V351-L483 HydrophobicContact CG2-CD1 3.99Å
352	F	89.2	Confident	86.7	Confident	86 Å²	86	59.8 Å²	59.8	38%	0.377	29%	0.289	S	S	.	.	I	π-helix	trans	-63.7	-51.1	178.6	176.9	-90.8	0	0	0	111.4	L348 Y349 D350 V354 I356 T357	L348-F352 VanDerWaalsContact O-CB 3.25Å; L348-F352 WeakPolarHBondContact O-CB 3.18Å; L348-F352 PolarHBondContact O-N 3.26Å; Y349-F352 PolarHBondContact O-N 2.85Å; D350-F352 PolarHBondContact O-N 3.42Å; F352-V354 VanDerWaalsContact C-N 3.33Å; F352-V354 PolarHBondContact O-N 3.1Å; F352-I356 HydrophobicContact CB-CD1 4.4Å; F352-I356 HydrophobicContact CD2-CB 3.9Å; F352-I356 HydrophobicContact CD2-CD1 3.71Å; F352-I356 HydrophobicContact CD2-CG1 4.37Å; F352-I356 HydrophobicContact CD2-CG2 3.85Å; F352-I356 HydrophobicContact CE2-CB 4.22Å; F352-I356 HydrophobicContact CE2-CD1 4.48Å; F352-I356 HydrophobicContact CE2-CG2 3.68Å; F352-I356 HydrophobicContact CG-CB 4.38Å; F352-I356 HydrophobicContact CG-CD1 4.45Å; F352-I356 HydrophobicContact CZ-CG2 4.42Å; F352-I356 WeakPolarHBondContact O-CA 3.42Å; F352-I356 VanDerWaalsContact O-CB 3.29Å; F352-I356 WeakPolarHBondContact O-CB 3.3Å; F352-I356 PolarHBondContact O-N 3.35Å; F352-T357 HydrophobicContact CD1-CG2 4.24Å; F352-T357 HydrophobicContact CE1-CG2 3.97Å; F352-T357 PolarHBondContact O-N 3.06Å; F352-T357 VanDerWaalsContact O-N 3.14Å
353	F	86.1	Confident	85.6	Confident	7 Å²	7	64.1 Å²	64.1	3%	0.031	31%	0.312	C	S	.	.	I	π-helix	trans	-69.8	-28.1	-177	-85.3	-81	0	0	0	113.2	C230 L233 V234 Y349 D350 T357 S366 I367 M368	C230-F353 HydrophobicContact CB-CE2 4.5Å; L233-F353 HydrophobicContact CB-CE1 4.31Å; L233-F353 HydrophobicContact CB-CZ 4.33Å; L233-F353 HydrophobicContact CD1-CD1 3.99Å; L233-F353 HydrophobicContact CD1-CD2 4.3Å; L233-F353 HydrophobicContact CD1-CE1 4.05Å; L233-F353 HydrophobicContact CD1-CE2 4.36Å; L233-F353 HydrophobicContact CD1-CG 4.12Å; L233-F353 HydrophobicContact CD1-CZ 4.24Å; V234-F353 HydrophobicContact CG2-CE1 4.12Å; V234-F353 HydrophobicContact CG2-CZ 4.03Å; Y349-F353 AromaticContact CD2-CD2 3.43Å; Y349-F353 HydrophobicContact CD2-CD2 3.43Å; Y349-F353 VanDerWaalsContact CD2-CD2 3.43Å; Y349-F353 AromaticContact CD2-CE2 3.5Å; Y349-F353 HydrophobicContact CD2-CE2 3.5Å; Y349-F353 VanDerWaalsContact CD2-CE2 3.5Å; Y349-F353 AromaticContact CE2-CD2 3.42Å; Y349-F353 HydrophobicContact CE2-CD2 3.42Å; Y349-F353 VanDerWaalsContact CE2-CD2 3.42Å; Y349-F353 AromaticContact CE2-CE2 3.41Å; Y349-F353 HydrophobicContact CE2-CE2 3.41Å; Y349-F353 VanDerWaalsContact CE2-CE2 3.41Å; Y349-F353 HydrophobicContact CE2-CG 4.4Å; Y349-F353 HydrophobicContact CE2-CZ 4.38Å; Y349-F353 HydrophobicContact CG-CD2 4.16Å; Y349-F353 WeakPolarHBondContact O-CD2 3.48Å; Y349-F353 PolarHBondContact O-N 3.11Å; D350-F353 PolarHBondContact O-N 3.41Å; F353-T357 HydrophobicContact CD1-CG2 3.78Å; F353-T357 HydrophobicContact CE1-CG2 4.31Å; F353-T357 HydrophobicContact CG-CG2 4.31Å; F353-T357 PolarHBondContact O-OG1 3.46Å; F353-S366 WeakPolarHBondContact O-CB 3.31Å; F353-I367 HydrophobicContact CD1-CB 4.26Å; F353-I367 HydrophobicContact CD1-CG2 4.34Å; F353-I367 HydrophobicContact CE1-CG2 4.33Å; F353-M368 HydrophobicContact CB-CB 4.32Å
354	V	83.6	Confident	84.6	Confident	22 Å²	22	66.5 Å²	66.5	13%	0.133	34%	0.337	C	S	.	.	I	π-helix	trans	-84.8	-49.6	177.2	177.2	0	0	0	0	112.8	D350 F352 P358 S366 M368 P480	D350-V354 WeakPolarHBondContact O-CB 3.33Å; D350-V354 VanDerWaalsContact O-CG2 3.29Å; D350-V354 WeakPolarHBondContact O-CG2 3.49Å; D350-V354 PolarHBondContact O-N 2.96Å; F352-V354 VanDerWaalsContact C-N 3.33Å; F352-V354 PolarHBondContact O-N 3.1Å; V354-P358 WeakPolarHBondContact O-CD 3.42Å; V354-P358 VanDerWaalsContact O-CG 3.29Å; V354-P358 WeakPolarHBondContact O-CG 3.31Å; V354-S366 WeakPolarHBondContact O-CB 3.47Å; V354-M368 HydrophobicContact CG2-SD 3.44Å; V354-M368 WeakPolarHBondContact CG2-SD 3.41Å; V354-P480 HydrophobicContact CB-CB 4.47Å; V354-P480 HydrophobicContact CB-CG 4.29Å; V354-P480 HydrophobicContact CG1-CG 4.32Å; V354-P480 HydrophobicContact CG2-CB 4.08Å; V354-P480 HydrophobicContact CG2-CG 4.41Å
355	F	85.3	Confident	83.7	Confident	94 Å²	94	65.9 Å²	65.9	41%	0.412	33%	0.331	S	S	.	.	I	π-helix	trans	-98.2	-29.7	-170.7	-62.6	-63.8	0	0	0	114.5	V351 F359 P480 L483	V351-F355 HydrophobicContact CG1-CD2 4.06Å; V351-F355 WeakPolarHBondContact O-CB 3.34Å; V351-F355 PolarHBondContact O-N 2.92Å; F355-F359 WeakPolarHBondContact O-CD2 3.24Å; F355-F359 VanDerWaalsContact O-CE2 3.29Å; F355-F359 WeakPolarHBondContact O-CE2 3.39Å; F355-P480 HydrophobicContact CD2-CG 4.32Å; F355-P480 HydrophobicContact CE2-CG 3.46Å; F355-P480 VanDerWaalsContact CE2-CG 3.46Å; F355-P480 HydrophobicContact CZ-CG 3.88Å; F355-L483 HydrophobicContact CE2-CD2 4.47Å
356	I	86.1	Confident	83.1	Confident	68 Å²	68	63.6 Å²	63.6	35%	0.349	32%	0.32	S	S	.	.	I	π-helix	trans	-91.8	-39.6	-173.8	-62.8	175.2	0	0	0	111.3	F352 F359 F360	F352-I356 HydrophobicContact CB-CD1 4.4Å; F352-I356 HydrophobicContact CD2-CB 3.9Å; F352-I356 HydrophobicContact CD2-CD1 3.71Å; F352-I356 HydrophobicContact CD2-CG1 4.37Å; F352-I356 HydrophobicContact CD2-CG2 3.85Å; F352-I356 HydrophobicContact CE2-CB 4.22Å; F352-I356 HydrophobicContact CE2-CD1 4.48Å; F352-I356 HydrophobicContact CE2-CG2 3.68Å; F352-I356 HydrophobicContact CG-CB 4.38Å; F352-I356 HydrophobicContact CG-CD1 4.45Å; F352-I356 HydrophobicContact CZ-CG2 4.42Å; F352-I356 WeakPolarHBondContact O-CA 3.42Å; F352-I356 VanDerWaalsContact O-CB 3.29Å; F352-I356 WeakPolarHBondContact O-CB 3.3Å; F352-I356 PolarHBondContact O-N 3.35Å; I356-F359 WeakPolarHBondContact O-CB 3.35Å; I356-F359 PolarHBondContact O-N 3.19Å; I356-F359 VanDerWaalsContact O-N 3.14Å; I356-F360 HydrophobicContact CG2-CD2 4.19Å; I356-F360 HydrophobicContact CG2-CE2 3.69Å; I356-F360 WeakPolarHBondContact O-CD2 3.3Å
357	T	85.2	Confident	82.6	Confident	3 Å²	3	63.9 Å²	63.9	2%	0.018	32%	0.321	C	S	.	.	G	3₁₀ helix	trans	-63.8	-27.1	-178.6	70.6	0	0	0	0	116.7	F352 F353 F359 F360 T361 S366 I367	F352-T357 HydrophobicContact CD1-CG2 4.24Å; F352-T357 HydrophobicContact CE1-CG2 3.97Å; F352-T357 PolarHBondContact O-N 3.06Å; F352-T357 VanDerWaalsContact O-N 3.14Å; F353-T357 HydrophobicContact CD1-CG2 3.78Å; F353-T357 HydrophobicContact CE1-CG2 4.31Å; F353-T357 HydrophobicContact CG-CG2 4.31Å; F353-T357 PolarHBondContact O-OG1 3.46Å; T357-F359 PolarHBondContact O-N 3.46Å; T357-F360 PolarHBondContact O-N 3.16Å; T357-T361 PolarHBondContact O-N 3.45Å; T357-T361 VanDerWaalsContact O-N 3.16Å; T357-T361 PolarHBondContact O-OG1 3.27Å; T357-S366 WeakPolarHBondContact OG1-CA 3.32Å; T357-S366 WeakPolarHBondContact OG1-CB 3.22Å; T357-I367 HydrophobicContact CG2-CB 4.4Å; T357-I367 HydrophobicContact CG2-CD1 3.92Å; T357-I367 HydrophobicContact CG2-CG1 4.29Å; T357-I367 PolarHBondContact OG1-N 2.8Å
358	P	83.8	Confident	81.9	Confident	32 Å²	32	65.2 Å²	65.2	21%	0.208	33%	0.327	C	S	.	.	G	3₁₀ helix	trans	-54	-34.6	170.1	-28.9	36.5	0	0	0	113.5	V354 F360 T361	V354-P358 WeakPolarHBondContact O-CD 3.42Å; V354-P358 VanDerWaalsContact O-CG 3.29Å; V354-P358 WeakPolarHBondContact O-CG 3.31Å; P358-F360 VanDerWaalsContact C-N 3.27Å; P358-F360 PolarHBondContact O-N 3.12Å; P358-T361 PolarHBondContact O-N 3.19Å
359	F	84.3	Confident	81.1	Confident	179 Å²	179	62.8 Å²	62.8	79%	0.785	32%	0.317	S	S	*	.	G	3₁₀ helix	trans	-70.3	-22.5	178.4	-65.2	-76.8	0	0	0	113.4	F355 I356 T357	F355-F359 WeakPolarHBondContact O-CD2 3.24Å; F355-F359 VanDerWaalsContact O-CE2 3.29Å; F355-F359 WeakPolarHBondContact O-CE2 3.39Å; I356-F359 WeakPolarHBondContact O-CB 3.35Å; I356-F359 PolarHBondContact O-N 3.19Å; I356-F359 VanDerWaalsContact O-N 3.14Å; T357-F359 PolarHBondContact O-N 3.46Å
360	F	81.4	Confident	80.4	Confident	161 Å²	161	61.6 Å²	61.6	71%	0.706	31%	0.313	S	S	*	.	T	Hydrogen-bonded Turn	trans	-94.4	-15.2	178.9	-70.3	-76.9	0	0	0	113.2	I356 T357 P358	I356-F360 HydrophobicContact CG2-CD2 4.19Å; I356-F360 HydrophobicContact CG2-CE2 3.69Å; I356-F360 WeakPolarHBondContact O-CD2 3.3Å; T357-F360 PolarHBondContact O-N 3.16Å; P358-F360 VanDerWaalsContact C-N 3.27Å; P358-F360 PolarHBondContact O-N 3.12Å
361	T	76.5	Confident	79.8	Confident	13 Å²	13	61.7 Å²	61.7	8%	0.08	31%	0.314	C	S	.	.	S	Bend	trans	-98.2	132.1	-172.9	-52.6	0	0	0	0	110.3	T357 P358 N363 G364 V365	T357-T361 PolarHBondContact O-N 3.45Å; T357-T361 VanDerWaalsContact O-N 3.16Å; T357-T361 PolarHBondContact O-OG1 3.27Å; P358-T361 PolarHBondContact O-N 3.19Å; T361-N363 PolarHBondContact O-N 3.44Å; T361-G364 PolarHBondContact O-N 2.91Å; T361-V365 WeakPolarHBondContact CB-O 3.49Å; T361-V365 PolarHBondContact OG1-O 2.95Å
362	K	73.1	Confident	78.8	Confident	208 Å²	208	62.2 Å²	62.2	90%	0.904	32%	0.322	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.5	-26.5	-177.6	-63.5	-175.8	-178.8	-179.6	0	114
363	N	67.4	Low	77.8	Confident	99 Å²	99	61.4 Å²	61.4	53%	0.529	32%	0.321	S	S	.	.	T	Hydrogen-bonded Turn	trans	-92.3	-3.7	-176	-58.6	-8.2	0	0	0	113.1	T361 V365	T361-N363 PolarHBondContact O-N 3.44Å; N363-V365 PolarHBondContact O-N 3.26Å
364	G	70.4	Confident	76.8	Confident	51 Å²	51	61 Å²	61	53%	0.526	32%	0.32	S	S	.	.	S	Bend	trans	66.6	10.1	-175.8	0	0	0	0	0	114.9	T361	T361-G364 PolarHBondContact O-N 2.91Å
365	V	73.3	Confident	75.8	Confident	42 Å²	42	62.5 Å²	62.5	26%	0.255	33%	0.33	S	S	.	.			trans	-100.5	142.1	176.1	-177.4	0	0	0	0	108.9	T361 N363 V369 Q370	T361-V365 WeakPolarHBondContact CB-O 3.49Å; T361-V365 PolarHBondContact OG1-O 2.95Å; N363-V365 PolarHBondContact O-N 3.26Å; V365-V369 HydrophobicContact CG1-CB 3.97Å; V365-V369 HydrophobicContact CG1-CG1 3.86Å; V365-Q370 HydrophobicContact CB-CG 4.19Å; V365-Q370 HydrophobicContact CG1-CG 3.82Å
366	S	80.6	Confident	74.3	Confident	9 Å²	9	62.7 Å²	62.7	6%	0.063	34%	0.335	C	S	.	.			trans	-66.5	146.4	178.1	59	0	0	0	0	112.1	F353 V354 T357 M368 V369 Q370	F353-S366 WeakPolarHBondContact O-CB 3.31Å; V354-S366 WeakPolarHBondContact O-CB 3.47Å; T357-S366 WeakPolarHBondContact OG1-CA 3.32Å; T357-S366 WeakPolarHBondContact OG1-CB 3.22Å; S366-M368 PolarHBondContact O-N 3.05Å; S366-V369 PolarHBondContact O-N 3.32Å; S366-V369 VanDerWaalsContact O-N 3.15Å; S366-V369 WeakPolarHBondContact OG-CB 3.26Å; S366-V369 WeakPolarHBondContact OG-CG2 3.44Å; S366-Q370 PolarHBondContact O-N 3.01Å; S366-Q370 VanDerWaalsContact O-N 3.14Å
367	I	79.8	Confident	72.6	Confident	21 Å²	21	60.4 Å²	60.4	11%	0.108	33%	0.327	C	S	.	.	H	α-helix	trans	-58.2	-39.2	177.1	-67.9	172.7	0	0	0	110.3	Y237 F353 T357 V369 Q370 V371	Y237-I367 HydrophobicContact CD2-CG1 4.15Å; Y237-I367 HydrophobicContact CD2-CG2 4.1Å; Y237-I367 HydrophobicContact CE2-CG1 4.33Å; Y237-I367 HydrophobicContact CG-CG2 4.3Å; F353-I367 HydrophobicContact CD1-CB 4.26Å; F353-I367 HydrophobicContact CD1-CG2 4.34Å; F353-I367 HydrophobicContact CE1-CG2 4.33Å; T357-I367 HydrophobicContact CG2-CB 4.4Å; T357-I367 HydrophobicContact CG2-CD1 3.92Å; T357-I367 HydrophobicContact CG2-CG1 4.29Å; T357-I367 PolarHBondContact OG1-N 2.8Å; I367-V369 VanDerWaalsContact C-N 3.32Å; I367-V369 PolarHBondContact O-N 3.17Å; I367-Q370 PolarHBondContact O-N 2.92Å; I367-V371 HydrophobicContact CG2-CG2 4.02Å; I367-V371 VanDerWaalsContact O-CB 3.25Å; I367-V371 WeakPolarHBondContact O-CB 3.42Å; I367-V371 VanDerWaalsContact O-CG2 3.25Å; I367-V371 WeakPolarHBondContact O-CG2 3.41Å; I367-V371 PolarHBondContact O-N 3.38Å
368	M	76.6	Confident	70.4	Confident	69 Å²	69	62.7 Å²	62.7	34%	0.34	34%	0.343	S	S	.	.	H	α-helix	trans	-59.2	-40.9	178.7	-178.1	175.9	176.6	0	0	112.6	F353 V354 S366 A372	F353-M368 HydrophobicContact CB-CB 4.32Å; V354-M368 HydrophobicContact CG2-SD 3.44Å; V354-M368 WeakPolarHBondContact CG2-SD 3.41Å; S366-M368 PolarHBondContact O-N 3.05Å; M368-A372 WeakPolarHBondContact O-CB 3.26Å; M368-A372 PolarHBondContact O-N 3.05Å
369	V	74.3	Confident	68.3	Low	64 Å²	64	63.3 Å²	63.3	39%	0.388	36%	0.355	S	S	.	.	H	α-helix	trans	-71.4	-45.1	179.2	171	0	0	0	0	110.8	V365 S366 I367 V371 A372 L373	V365-V369 HydrophobicContact CG1-CB 3.97Å; V365-V369 HydrophobicContact CG1-CG1 3.86Å; S366-V369 PolarHBondContact O-N 3.32Å; S366-V369 VanDerWaalsContact O-N 3.15Å; S366-V369 WeakPolarHBondContact OG-CB 3.26Å; S366-V369 WeakPolarHBondContact OG-CG2 3.44Å; I367-V369 VanDerWaalsContact C-N 3.32Å; I367-V369 PolarHBondContact O-N 3.17Å; V369-V371 VanDerWaalsContact C-N 3.29Å; V369-V371 PolarHBondContact O-N 3.49Å; V369-A372 PolarHBondContact O-N 3.49Å; V369-L373 HydrophobicContact CG1-CD1 3.76Å; V369-L373 WeakPolarHBondContact O-CB 3.48Å; V369-L373 WeakPolarHBondContact O-CG 3.43Å; V369-L373 PolarHBondContact O-N 2.91Å
370	Q	74	Confident	66.1	Low	22 Å²	22	60.8 Å²	60.8	10%	0.103	35%	0.345	C	S	.	.	H	α-helix	trans	-63	-37.2	178.2	-68.5	-170.4	8	0	0	112.6	Y237 V365 S366 I367 G374	Y237-Q370 VanDerWaalsContact CE2-OE1 3.23Å; V365-Q370 HydrophobicContact CB-CG 4.19Å; V365-Q370 HydrophobicContact CG1-CG 3.82Å; S366-Q370 PolarHBondContact O-N 3.01Å; S366-Q370 VanDerWaalsContact O-N 3.14Å; I367-Q370 PolarHBondContact O-N 2.92Å; Q370-G374 CarbonylContact O-C 3.12Å; Q370-G374 WeakPolarHBondContact O-CA 3.5Å; Q370-G374 PolarHBondContact O-N 3.48Å
371	V	75.9	Confident	63.9	Low	7 Å²	7	60.3 Å²	60.3	4%	0.042	34%	0.343	C	S	.	.	H	α-helix	trans	-71.9	-41.5	176.2	163.6	0	0	0	0	111.4	L233 M236 Y240 I367 V369 L373 I400	L233-V371 HydrophobicContact CD2-CG1 4.23Å; M236-V371 HydrophobicContact CE-CB 4.41Å; M236-V371 HydrophobicContact CE-CG1 3.04Å; M236-V371 HydrophobicContact CG-CG1 4.01Å; M236-V371 HydrophobicContact CG-CG2 4.4Å; M236-V371 HydrophobicContact SD-CG1 3.75Å; Y240-V371 WeakPolarHBondContact CE2-O 3.1Å; I367-V371 HydrophobicContact CG2-CG2 4.02Å; I367-V371 VanDerWaalsContact O-CB 3.25Å; I367-V371 WeakPolarHBondContact O-CB 3.42Å; I367-V371 VanDerWaalsContact O-CG2 3.25Å; I367-V371 WeakPolarHBondContact O-CG2 3.41Å; I367-V371 PolarHBondContact O-N 3.38Å; V369-V371 VanDerWaalsContact C-N 3.29Å; V369-V371 PolarHBondContact O-N 3.49Å; V371-L373 VanDerWaalsContact C-N 3.34Å; V371-L373 PolarHBondContact O-N 3Å; V371-I400 HydrophobicContact CG1-CD1 3.63Å; V371-I400 WeakPolarHBondContact O-CD1 3.28Å
372	A	67.9	Low	62	Low	50 Å²	50	65.9 Å²	65.9	41%	0.413	38%	0.377	S	S	.	.	H	α-helix	trans	-67.9	-34.1	-178.4	0	0	0	0	0	113.1	M368 V369	M368-A372 WeakPolarHBondContact O-CB 3.26Å; M368-A372 PolarHBondContact O-N 3.05Å; V369-A372 PolarHBondContact O-N 3.49Å
373	L	67.3	Low	59.8	Low	68 Å²	68	63.6 Å²	63.6	36%	0.356	37%	0.37	S	S	.	.	H	α-helix	trans	-101.4	-15.1	-176.3	-58.2	176.1	0	0	0	113.5	V369 V371 A377	V369-L373 HydrophobicContact CG1-CD1 3.76Å; V369-L373 WeakPolarHBondContact O-CB 3.48Å; V369-L373 WeakPolarHBondContact O-CG 3.43Å; V369-L373 PolarHBondContact O-N 2.91Å; V371-L373 VanDerWaalsContact C-N 3.34Å; V371-L373 PolarHBondContact O-N 3Å; L373-A377 HydrophobicContact CB-CB 3.47Å; L373-A377 VanDerWaalsContact CB-CB 3.47Å; L373-A377 VanDerWaalsContact O-CB 3.28Å; L373-A377 WeakPolarHBondContact O-CB 3.32Å
374	G	66.3	Low	58.3	Low	0 Å²	0	61.7 Å²	61.7	0%	0	37%	0.373	C	S	.	.			trans	91.5	159.3	-175.1	0	0	0	0	0	113.1	Q370 D376 A377	Q370-G374 CarbonylContact O-C 3.12Å; Q370-G374 WeakPolarHBondContact O-CA 3.5Å; Q370-G374 PolarHBondContact O-N 3.48Å; G374-D376 VanDerWaalsContact C-N 3.27Å; G374-D376 PolarHBondContact O-N 2.92Å; G374-A377 PolarHBondContact O-N 3.43Å
375	P	61.4	Low	56.6	Low	53 Å²	53	65.2 Å²	65.2	34%	0.344	38%	0.38	S	S	.	.	G	3₁₀ helix	trans	-61.5	-32.1	-174.7	21	-30.6	0	0	0	113.6	Y240 S378	Y240-P375 HydrophobicContact CD1-CG 4.09Å; Y240-P375 HydrophobicContact CG-CG 4.27Å; P375-S378 PolarHBondContact O-OG 2.93Å
376	D	55.5	Low	54.8	Low	97 Å²	97	68.8 Å²	68.8	52%	0.519	40%	0.396	S	S	.	.	G	3₁₀ helix	trans	-83.7	-14.9	-177.5	-58.6	-39.8	0	0	0	113.6	G374 S378	G374-D376 VanDerWaalsContact C-N 3.27Å; G374-D376 PolarHBondContact O-N 2.92Å; D376-S378 PolarHBondContact O-N 3.08Å
377	A	49.8	Very low	53.4	Low	21 Å²	21	70.3 Å²	70.3	17%	0.174	40%	0.404	C	S	.	.	G	3₁₀ helix	trans	-74.1	-5.3	174.6	0	0	0	0	0	113	L373 G374 G379 E380	L373-A377 HydrophobicContact CB-CB 3.47Å; L373-A377 VanDerWaalsContact CB-CB 3.47Å; L373-A377 VanDerWaalsContact O-CB 3.28Å; L373-A377 WeakPolarHBondContact O-CB 3.32Å; G374-A377 PolarHBondContact O-N 3.43Å; A377-G379 PolarHBondContact O-N 2.77Å; A377-E380 WeakPolarHBondContact O-CB 3.35Å; A377-E380 PolarHBondContact O-N 3.31Å
378	S	38.8	Very low	51.7	Low	51 Å²	51	74.1 Å²	74.1	36%	0.357	42%	0.422	S	S	.	.	G	3₁₀ helix	trans	-68.9	-6.2	177.3	63.9	0	0	0	0	114.7	P375 D376	P375-S378 PolarHBondContact O-OG 2.93Å; D376-S378 PolarHBondContact O-N 3.08Å
379	G	38.8	Very low	50.6	Low	44 Å²	44	71.6 Å²	71.6	45%	0.454	41%	0.409	S	S	.	.	G	3₁₀ helix	trans	-77.6	-18.4	166.9	0	0	0	0	0	113.6	A377 K381	A377-G379 PolarHBondContact O-N 2.77Å; G379-K381 PolarHBondContact O-N 3.13Å
380	E	39.5	Very low	49.4	Very low	127 Å²	127	70.5 Å²	70.5	59%	0.593	40%	0.403	S	S	*	.			trans	-81.6	68.1	177.4	-161.1	177	-174.3	0	0	109.8	A377 T382	A377-E380 WeakPolarHBondContact O-CB 3.35Å; A377-E380 PolarHBondContact O-N 3.31Å; E380-T382 VanDerWaalsContact C-N 3.25Å; E380-T382 PolarHBondContact O-N 3.26Å
381	K	35.4	Very low	47.9	Very low	151 Å²	151	70 Å²	70	66%	0.657	40%	0.404	S	S	*	.			trans	-66.9	91.6	167.6	-77.3	-176.3	179.4	177.2	0	108.2	G379 Q383	G379-K381 PolarHBondContact O-N 3.13Å; K381-Q383 PolarHBondContact O-N 3.08Å
382	T	35.5	Very low	46.1	Very low	130 Å²	130	76.8 Å²	76.8	80%	0.798	44%	0.435	S	S	*	.			trans	-68.3	57.7	161.9	-42	0	0	0	0	109.5	E380	E380-T382 VanDerWaalsContact C-N 3.25Å; E380-T382 PolarHBondContact O-N 3.26Å
383	Q	26.9	Very low	44.9	Very low	159 Å²	159	79.1 Å²	79.1	74%	0.743	45%	0.445	S	S	*	.			trans	-118.8	85.1	176.3	-164.9	174.2	15.1	0	0	107.4	K381	K381-Q383 PolarHBondContact O-N 3.08Å
384	G	35.3	Very low	43.6	Very low	59 Å²	59	80.5 Å²	80.5	61%	0.608	45%	0.45	S	S	*	.	S	Bend	trans	56.2	110.7	162.2	0	0	0	0	0	117.1	M386	G384-M386 PolarHBondContact O-N 3.16Å
385	N	35.8	Very low	42.3	Very low	126 Å²	126	85.4 Å²	85.4	67%	0.674	48%	0.482	S	S	*	.	S	Bend	trans	66.3	18	161	-54	-4.9	0	0	0	117.7	Q24	Q24-N385 VanDerWaalsContact CD-O 3.24Å; Q24-N385 PolarHBondContact NE2-O 2.93Å; Q24-N385 PolarHBondContact OE1-O 3.04Å
386	M	34.9	Very low	41.7	Very low	117 Å²	117	86.7 Å²	86.7	58%	0.576	49%	0.49	S	S	*	.			trans	-137.4	132	167.1	-61.4	-171.5	-156	0	0	110.2	T120 G384	T120-M386 WeakPolarHBondContact OG1-CA 3.29Å; T120-M386 WeakPolarHBondContact OG1-CB 3.27Å; G384-M386 PolarHBondContact O-N 3.16Å
387	V	51.1	Low	41.5	Very low	40 Å²	40	83.4 Å²	83.4	24%	0.242	48%	0.475	C	S	.	.			trans	-114	123.3	179.9	178.5	0	0	0	0	107.9	Q24 T120 I389	Q24-V387 HydrophobicContact CB-CG2 4.24Å; T120-V387 HydrophobicContact CG2-CB 3.87Å; T120-V387 HydrophobicContact CG2-CG2 4.41Å; T120-V387 PolarHBondContact N-O 3.27Å; V387-I389 HydrophobicContact CG1-CD1 4.21Å; V387-I389 HydrophobicContact CG1-CG1 3.9Å
388	E	44.9	Very low	42.3	Very low	102 Å²	102	83.1 Å²	83.1	48%	0.477	47%	0.47	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-110.4	114.6	174.8	-65.2	-167.9	-178.5	0	0	109.9	L118 V119	L118-E388 CarbonylContact O-C 3.52Å; L118-E388 VanDerWaalsContact O-CA 3.29Å; L118-E388 WeakPolarHBondContact O-CA 3.3Å; V119-E388 HydrophobicContact CG2-CG 4.31Å
389	I	53.1	Low	43.9	Very low	15 Å²	15	84.4 Å²	84.4	8%	0.077	47%	0.469	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-113.2	115.1	177.5	-59	176.6	0	0	0	108.8	V42 T117 L118 V387 A391 C417	V42-I389 HydrophobicContact CG2-CD1 3.63Å; V42-I389 HydrophobicContact CG2-CG1 4.31Å; T117-I389 CarbonylContact C-O 3.55Å; T117-I389 WeakPolarHBondContact CA-O 3.47Å; L118-I389 HydrophobicContact CB-CB 4.09Å; L118-I389 WeakPolarHBondContact CB-O 3.42Å; L118-I389 HydrophobicContact CD1-CB 4.06Å; L118-I389 HydrophobicContact CD1-CG2 4.09Å; L118-I389 PolarHBondContact N-O 2.76Å; L118-I389 PolarHBondContact O-N 3.44Å; V387-I389 HydrophobicContact CG1-CD1 4.21Å; V387-I389 HydrophobicContact CG1-CG1 3.9Å; I389-A391 PolarHBondContact O-N 3.49Å; I389-C417 HydrophobicContact CD1-CB 3.96Å
390	P	48.3	Very low	45.6	Very low	41 Å²	41	83.1 Å²	83.1	27%	0.266	45%	0.452	S	S	.	.			trans	-55.5	132.1	176.7	-23.8	32.8	0	0	0	112.8	T117 R139 E392 Q394	T117-P390 HydrophobicContact CG2-CB 4.25Å; R139-P390 PolarHBondContact NE-O 3.47Å; R139-P390 PolarHBondContact NH1-O 2.83Å; R139-P390 PolarHBondContact NH2-O 3.3Å; R139-P390 VanDerWaalsContact NH2-O 3.17Å; P390-E392 WeakPolarHBondContact CB-O 3.34Å; P390-Q394 HydrophobicContact CB-CG 4.1Å; P390-Q394 HydrophobicContact CG-CG 4.26Å
391	A	42.9	Very low	47.5	Very low	13 Å²	13	77.1 Å²	77.1	11%	0.107	42%	0.424	C	S	.	.	S	Bend	trans	-80.5	-24.9	179.7	0	0	0	0	0	113.7	N115 T116 I389	N115-A391 VanDerWaalsContact C-CB 3.47Å; N115-A391 WeakPolarHBondContact O-CB 3.15Å; T116-A391 WeakPolarHBondContact O-CB 3.4Å; I389-A391 PolarHBondContact O-N 3.49Å
392	E	38.5	Very low	49.6	Very low	149 Å²	149	73.1 Å²	73.1	70%	0.696	41%	0.412	S	S	*	.	S	Bend	trans	-99.9	143.2	165.2	-73.2	-178.2	153.7	0	0	109.1	P390 Q394	P390-E392 WeakPolarHBondContact CB-O 3.34Å; E392-Q394 PolarHBondContact O-N 3.41Å
393	P	43.1	Very low	52	Low	98 Å²	98	68.1 Å²	68.1	64%	0.636	38%	0.381	S	S	*	.			trans	-57.5	108.8	162.5	24.3	-28.1	0	0	0	106.5
394	Q	39.4	Very low	54.7	Low	98 Å²	98	60.6 Å²	60.6	46%	0.458	35%	0.346	S	S	.	.			trans	-51.1	144.7	168.9	-72.7	-178.4	-27.8	0	0	107.6	P390 E392 P396	P390-Q394 HydrophobicContact CB-CG 4.1Å; P390-Q394 HydrophobicContact CG-CG 4.26Å; E392-Q394 PolarHBondContact O-N 3.41Å; Q394-P396 VanDerWaalsContact O-N 3.08Å
395	P	38.6	Very low	57	Low	103 Å²	103	58.5 Å²	58.5	67%	0.669	32%	0.32	S	S	*	.			trans	-47.8	127.2	170.9	22.2	-32	0	0	0	106.6	S397	P395-S397 PolarHBondContact O-N 3.18Å
396	P	49.1	Very low	59.3	Low	79 Å²	79	52.5 Å²	52.5	51%	0.513	29%	0.288	S	S	.	.			trans	-55.9	106.8	-169.3	20.4	-31.4	0	0	0	107.5	N307 Q394 E398	N307-P396 HydrophobicContact CB-CB 4.2Å; N307-P396 HydrophobicContact CB-CG 4.5Å; Q394-P396 VanDerWaalsContact O-N 3.08Å; P396-E398 PolarHBondContact O-N 2.74Å
397	S	52.3	Low	61.4	Low	29 Å²	29	47.4 Å²	47.4	20%	0.203	26%	0.263	C	S	.	.			trans	-61.6	115.2	169.7	52.1	0	0	0	0	104.4	P395 K399	P395-S397 PolarHBondContact O-N 3.18Å; S397-K399 WeakPolarHBondContact O-CG 3.48Å; S397-K399 PolarHBondContact O-N 2.79Å
398	E	66.8	Low	62.4	Low	15 Å²	15	49.4 Å²	49.4	7%	0.07	27%	0.266	C	S	.	.			trans	-57	115.1	-174.4	-75.1	-68.3	165.5	0	0	108.2	Y240 V244 Y245 R306 P396	Y240-E398 PolarHBondContact OH-O 2.87Å; V244-E398 HydrophobicContact CB-CB 4.37Å; V244-E398 HydrophobicContact CG1-CB 3.83Å; V244-E398 HydrophobicContact CG1-CG 4.35Å; V244-E398 HydrophobicContact CG2-CB 3.63Å; Y245-E398 HydrophobicContact CE1-CG 4.01Å; R306-E398 IonicContact CZ-OE1 3.49Å; R306-E398 IonicContact CZ-OE2 2.85Å; R306-E398 IonicContact NE-OE1 2.72Å; R306-E398 PolarHBondContact NE-OE1 3.39Å; R306-E398 IonicContact NE-OE2 2.69Å; R306-E398 PolarHBondContact NE-OE2 3.18Å; R306-E398 VanDerWaalsContact NH2-CD 3.34Å; R306-E398 IonicContact NH2-OE1 3.41Å; R306-E398 PolarHBondContact NH2-OE1 3.16Å; R306-E398 IonicContact NH2-OE2 3.47Å; R306-E398 PolarHBondContact NH2-OE2 2.89Å; P396-E398 PolarHBondContact O-N 2.74Å
399	K	71.1	Confident	63.5	Low	77 Å²	77	49 Å²	49	34%	0.335	26%	0.263	S	S	.	.			trans	-87.8	130.7	-175.6	-55.3	177	-171.7	165.5	0	109.1	D309 S397	D309-K399 VanDerWaalsContact CG-NZ 3.33Å; D309-K399 IonicContact OD1-NZ 2.74Å; D309-K399 PolarHBondContact OD1-NZ 3.32Å; D309-K399 IonicContact OD2-NZ 3.41Å; D309-K399 PolarHBondContact OD2-NZ 2.94Å; S397-K399 WeakPolarHBondContact O-CG 3.48Å; S397-K399 PolarHBondContact O-N 2.79Å
400	I	76.1	Confident	63.7	Low	17 Å²	17	51.1 Å²	51.1	9%	0.087	28%	0.279	C	S	.	.			trans	-63.9	134.3	179.4	-59.9	172.7	0	0	0	110.3	M236 Y240 V244 I247 V371 V402 R405	M236-I400 HydrophobicContact CE-CD1 3.75Å; M236-I400 HydrophobicContact SD-CD1 3.32Å; M236-I400 WeakPolarHBondContact SD-CD1 3.31Å; M236-I400 HydrophobicContact SD-CG1 4.25Å; Y240-I400 HydrophobicContact CE2-CD1 4.22Å; Y240-I400 HydrophobicContact CE2-CG1 4.48Å; V244-I400 HydrophobicContact CG2-CG1 4.38Å; I247-I400 HydrophobicContact CG2-CG2 4.36Å; V371-I400 HydrophobicContact CG1-CD1 3.63Å; V371-I400 WeakPolarHBondContact O-CD1 3.28Å; I400-V402 HydrophobicContact CG2-CB 3.87Å; I400-V402 HydrophobicContact CG2-CG2 3.44Å; I400-V402 VanDerWaalsContact CG2-CG2 3.44Å; I400-V402 PolarHBondContact O-N 2.92Å; I400-R405 PolarHBondContact O-NH2 2.95Å
401	P	77.9	Confident	64	Low	1 Å²	1	49.1 Å²	49.1	1%	0.006	27%	0.267	C	S	.	.	S	Bend	trans	-82.9	16.3	-175.6	34.2	-37.8	0	0	0	114.8	I248 F251 W302 V403 Y426	I248-P401 HydrophobicContact CG1-CG 4.43Å; F251-P401 HydrophobicContact CB-CG 3.83Å; F251-P401 HydrophobicContact CD1-CB 3.74Å; F251-P401 HydrophobicContact CD1-CG 3.79Å; F251-P401 HydrophobicContact CD2-CB 4.36Å; F251-P401 HydrophobicContact CD2-CG 4.17Å; F251-P401 HydrophobicContact CE1-CB 3.82Å; F251-P401 HydrophobicContact CE1-CG 4.37Å; F251-P401 HydrophobicContact CE2-CB 4.46Å; F251-P401 HydrophobicContact CG-CB 4Å; F251-P401 HydrophobicContact CG-CG 3.65Å; F251-P401 HydrophobicContact CZ-CB 4.18Å; W302-P401 HydrophobicContact CH2-CB 3.34Å; W302-P401 HydrophobicContact CH2-CG 3.84Å; W302-P401 HydrophobicContact CZ2-CB 3.49Å; W302-P401 VanDerWaalsContact CZ2-CB 3.49Å; W302-P401 HydrophobicContact CZ2-CG 4.46Å; W302-P401 HydrophobicContact CZ3-CB 4.49Å; P401-V403 PolarHBondContact O-N 3.48Å; P401-V403 VanDerWaalsContact O-N 3.11Å; P401-Y426 WeakPolarHBondContact O-CE2 3.44Å; P401-Y426 PolarHBondContact O-OH 3.25Å
402	V	79.1	Confident	64.7	Low	67 Å²	67	55.6 Å²	55.6	41%	0.406	29%	0.288	S	S	.	.			trans	-85.6	20.2	-169.5	-176.6	0	0	0	0	112.5	I400 Y426	I400-V402 HydrophobicContact CG2-CB 3.87Å; I400-V402 HydrophobicContact CG2-CG2 3.44Å; I400-V402 VanDerWaalsContact CG2-CG2 3.44Å; I400-V402 PolarHBondContact O-N 2.92Å; V402-Y426 HydrophobicContact CB-CD2 4.5Å; V402-Y426 HydrophobicContact CG1-CD2 4.34Å; V402-Y426 WeakPolarHBondContact O-CD2 2.98Å; V402-Y426 PolarHBondContact O-N 3.39Å
403	V	85.9	Confident	65.3	Low	26 Å²	26	48.8 Å²	48.8	16%	0.158	26%	0.257	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-138.1	145.6	-171.8	-58.3	0	0	0	0	112.5	Q316 P401 R405 I423 L424 Y426	Q316-V403 PolarHBondContact NE2-O 3.39Å; P401-V403 PolarHBondContact O-N 3.48Å; P401-V403 VanDerWaalsContact O-N 3.11Å; V403-R405 HydrophobicContact CG2-CG 4.02Å; V403-I423 HydrophobicContact CB-CG2 3.53Å; V403-I423 HydrophobicContact CG1-CG2 3.69Å; V403-I423 HydrophobicContact CG2-CG2 3.79Å; V403-L424 CarbonylContact C-O 3.53Å; V403-L424 WeakPolarHBondContact CA-O 3.25Å; V403-Y426 VanDerWaalsContact C-CE1 3.41Å; V403-Y426 PolarHBondContact O-OH 2.93Å
404	M	85.1	Confident	65.8	Low	0 Å²	0	44.5 Å²	44.5	0%	0	23%	0.229	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-78.5	140.4	162.8	-67.8	-170.3	175.6	0	0	109.6	L173 I176 N317 I321 I423 L424 Y426 I429	L173-M404 HydrophobicContact CD1-CB 4Å; I176-M404 HydrophobicContact CG2-CE 4.07Å; I176-M404 HydrophobicContact CG2-SD 3.58Å; I176-M404 VanDerWaalsContact CG2-SD 3.58Å; N317-M404 WeakPolarHBondContact OD1-CA 3.5Å; I321-M404 HydrophobicContact CG1-CE 3.82Å; M404-I423 WeakPolarHBondContact O-CA 3.38Å; M404-L424 HydrophobicContact CB-CB 4.49Å; M404-L424 PolarHBondContact N-O 3.42Å; M404-L424 PolarHBondContact O-N 3.43Å; M404-L424 VanDerWaalsContact O-N 3.09Å; M404-Y426 HydrophobicContact CB-CE1 4.43Å; M404-Y426 HydrophobicContact CE-CD1 4.49Å; M404-Y426 HydrophobicContact CE-CE1 4.43Å; M404-Y426 HydrophobicContact CG-CD1 3.93Å; M404-Y426 HydrophobicContact CG-CE1 3.54Å; M404-I429 HydrophobicContact CE-CD1 3.38Å; M404-I429 HydrophobicContact CG-CD1 4.22Å; M404-I429 HydrophobicContact SD-CD1 3.37Å; M404-I429 WeakPolarHBondContact SD-CD1 3.31Å
405	R	83.1	Confident	66.6	Low	16 Å²	16	41.8 Å²	41.8	6%	0.06	22%	0.217	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-129.1	125.5	-179.1	-62.9	-174.1	-175.7	157.1	10	110.1	W313 N317 I400 V403 F421 S422	W313-R405 HydrophobicContact CB-CB 4.46Å; N317-R405 PolarHBondContact ND2-O 3.44Å; N317-R405 PolarHBondContact OD1-N 2.96Å; N317-R405 PolarHBondContact OD1-O 2.86Å; I400-R405 PolarHBondContact O-NH2 2.95Å; V403-R405 HydrophobicContact CG2-CG 4.02Å; R405-F421 HydrophobicContact CB-CB 4.23Å; R405-F421 HydrophobicContact CB-CD1 3.79Å; R405-F421 HydrophobicContact CB-CE1 4.47Å; R405-F421 HydrophobicContact CB-CG 4.16Å; R405-S422 WeakPolarHBondContact CA-O 3.37Å
406	V	83.9	Confident	67.6	Low	0 Å²	0	39.6 Å²	39.6	0%	0	20%	0.199	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-126.6	122.5	173.5	-176	0	0	0	0	108.8	N169 V172 L173 I176 F409 S422	N169-V406 HydrophobicContact CB-CB 4.4Å; N169-V406 HydrophobicContact CB-CG1 3.78Å; N169-V406 PolarHBondContact ND2-O 2.88Å; V172-V406 HydrophobicContact CB-CG1 4.32Å; V172-V406 HydrophobicContact CG1-CG1 4.03Å; V172-V406 HydrophobicContact CG1-CG2 4.45Å; L173-V406 HydrophobicContact CB-CG2 4.33Å; L173-V406 HydrophobicContact CD1-CG2 3.91Å; I176-V406 HydrophobicContact CD1-CG2 4.28Å; V406-F409 HydrophobicContact CG1-CE2 3.57Å; V406-F409 HydrophobicContact CG1-CZ 3.88Å; V406-S422 PolarHBondContact N-O 3.47Å; V406-S422 PolarHBondContact O-N 3.43Å
407	P	78.3	Confident	67.9	Low	9 Å²	9	36.2 Å²	36.2	6%	0.058	18%	0.177	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-64.3	147.8	-179.7	29.2	-36.4	0	0	0	110.7	N169 W313 F409 L419 F421	N169-P407 WeakPolarHBondContact CB-O 3.27Å; W313-P407 HydrophobicContact CD2-CG 4.32Å; W313-P407 HydrophobicContact CH2-CG 4.31Å; W313-P407 HydrophobicContact CZ2-CG 3.94Å; P407-F409 HydrophobicContact CG-CE1 4.01Å; P407-F409 HydrophobicContact CG-CZ 4.25Å; P407-F409 PolarHBondContact O-N 3.25Å; P407-F409 VanDerWaalsContact O-N 3.11Å; P407-L419 HydrophobicContact CB-CD2 3.71Å; P407-F421 HydrophobicContact CB-CD1 4.21Å; P407-F421 HydrophobicContact CB-CE1 4.02Å
408	R	72.4	Confident	68.2	Low	82 Å²	82	36.6 Å²	36.6	31%	0.309	19%	0.186	S	C	.	.			trans	-68.5	105.7	172.1	-76.1	-178.2	173.7	179.7	-4.8	110	D167 N169 A411 N415 Q420	D167-R408 VanDerWaalsContact OD2-CD 3.25Å; D167-R408 WeakPolarHBondContact OD2-CD 3.19Å; D167-R408 WeakPolarHBondContact OD2-CG 3.17Å; D167-R408 IonicContact OD2-NE 3.65Å; D167-R408 PolarHBondContact OD2-NE 2.83Å; N169-R408 WeakPolarHBondContact ND2-CA 3.22Å; N169-R408 WeakPolarHBondContact ND2-CG 3.18Å; R408-A411 HydrophobicContact CB-CB 4.08Å; R408-N415 PolarHBondContact O-ND2 3.48Å; R408-Q420 PolarHBondContact N-O 3.42Å
409	F	68.1	Low	67.7	Low	94 Å²	94	38.9 Å²	38.9	41%	0.412	20%	0.199	S	C	.	.	S	Bend	trans	-70.4	-35.2	-176.9	-62.1	-69.6	0	0	0	113.5	L168 N169 V172 V406 P407 A411	L168-F409 HydrophobicContact CD2-CD2 3.65Å; L168-F409 HydrophobicContact CD2-CE2 4.17Å; L168-F409 HydrophobicContact CD2-CG 4.34Å; N169-F409 HydrophobicContact CB-CD2 3.91Å; N169-F409 HydrophobicContact CB-CE2 4.15Å; V172-F409 HydrophobicContact CB-CE2 4.39Å; V172-F409 HydrophobicContact CG2-CE2 4.05Å; V406-F409 HydrophobicContact CG1-CE2 3.57Å; V406-F409 HydrophobicContact CG1-CZ 3.88Å; P407-F409 HydrophobicContact CG-CE1 4.01Å; P407-F409 HydrophobicContact CG-CZ 4.25Å; P407-F409 PolarHBondContact O-N 3.25Å; P407-F409 VanDerWaalsContact O-N 3.11Å; F409-A411 VanDerWaalsContact C-N 3.34Å
410	S	56.7	Low	67.4	Low	59 Å²	59	38 Å²	38	41%	0.413	20%	0.196	S	C	.	.	S	Bend	trans	-77.2	-17.8	-178.2	20.8	0	0	0	0	113.5	D167 W412	D167-S410 WeakPolarHBondContact CB-OG 3.23Å; D167-S410 WeakPolarHBondContact OD1-CB 3.49Å; D167-S410 PolarHBondContact OD1-OG 3.47Å; S410-W412 PolarHBondContact O-N 3.07Å
411	A	55.8	Low	67.1	Low	0 Å²	0	38.9 Å²	38.9	0%	0	20%	0.199	C	C	.	.			trans	-103.8	61.2	-177.3	0	0	0	0	0	111.2	Y163 R408 F409 T413 Q414 N415	Y163-A411 HydrophobicContact CD1-CB 4.01Å; Y163-A411 HydrophobicContact CE1-CB 3.86Å; R408-A411 HydrophobicContact CB-CB 4.08Å; F409-A411 VanDerWaalsContact C-N 3.34Å; A411-T413 PolarHBondContact O-N 3.4Å; A411-Q414 HydrophobicContact CB-CB 3.66Å; A411-Q414 HydrophobicContact CB-CG 3.96Å; A411-Q414 PolarHBondContact O-N 3.13Å; A411-Q414 VanDerWaalsContact O-N 3.11Å; A411-N415 PolarHBondContact O-N 3.33Å; A411-N415 PolarHBondContact O-ND2 3.31Å
412	W	56.6	Low	66.9	Low	148 Å²	148	39.6 Å²	39.6	56%	0.561	20%	0.204	S	C	*	.	H	α-helix	trans	-54.7	-37.8	178.6	-176.8	75.7	0	0	0	112.2	D38 S410 N415 L416	D38-W412 HydrophobicContact CB-CH2 3.76Å; D38-W412 HydrophobicContact CB-CZ3 4.11Å; D38-W412 WeakPolarHBondContact OD2-CH2 3.36Å; D38-W412 WeakPolarHBondContact OD2-CZ3 3.46Å; S410-W412 PolarHBondContact O-N 3.07Å; W412-N415 PolarHBondContact O-N 2.91Å; W412-L416 HydrophobicContact CD2-CD1 3.91Å; W412-L416 HydrophobicContact CE3-CD1 3.71Å; W412-L416 HydrophobicContact CH2-CD1 3.87Å; W412-L416 HydrophobicContact CZ2-CD1 4.03Å; W412-L416 HydrophobicContact CZ3-CD1 3.69Å; W412-L416 WeakPolarHBondContact O-CD1 3.38Å; W412-L416 PolarHBondContact O-N 2.9Å
413	T	52.4	Low	67.1	Low	7 Å²	7	40.6 Å²	40.6	4%	0.043	21%	0.206	C	C	.	.	H	α-helix	trans	-69.6	-38.1	175.8	46.7	0	0	0	0	113.8	V27 Y159 P161 Y163 A411 L416 C417	V27-T413 HydrophobicContact CB-CG2 4.13Å; V27-T413 HydrophobicContact CG2-CG2 3.15Å; Y159-T413 HydrophobicContact CE2-CG2 4.34Å; P161-T413 HydrophobicContact CG-CG2 3.59Å; Y163-T413 VanDerWaalsContact CE1-OG1 3.25Å; Y163-T413 WeakPolarHBondContact CE1-OG1 3.4Å; Y163-T413 VanDerWaalsContact CZ-OG1 3.29Å; Y163-T413 WeakPolarHBondContact OH-CB 3.39Å; Y163-T413 PolarHBondContact OH-OG1 3.39Å; A411-T413 PolarHBondContact O-N 3.4Å; T413-L416 VanDerWaalsContact O-CB 3.29Å; T413-L416 WeakPolarHBondContact O-CB 3.39Å; T413-L416 PolarHBondContact O-N 2.9Å; T413-C417 PolarHBondContact O-N 3.47Å
414	Q	53.7	Low	67.1	Low	8 Å²	8	39.7 Å²	39.7	4%	0.037	20%	0.201	C	C	.	.	H	α-helix	trans	-66.3	-43.1	169.4	-80.6	165.7	1	0	0	110.6	E25 Y163 A411 L416 C417 G418 Q420	E25-Q414 WeakPolarHBondContact OE2-CA 3.28Å; E25-Q414 WeakPolarHBondContact OE2-CG 3Å; Y163-Q414 HydrophobicContact CE1-CG 4.36Å; A411-Q414 HydrophobicContact CB-CB 3.66Å; A411-Q414 HydrophobicContact CB-CG 3.96Å; A411-Q414 PolarHBondContact O-N 3.13Å; A411-Q414 VanDerWaalsContact O-N 3.11Å; Q414-L416 PolarHBondContact O-N 3.3Å; Q414-L416 VanDerWaalsContact O-N 3.13Å; Q414-C417 CarbonylContact O-C 3.43Å; Q414-C417 VanDerWaalsContact O-CA 3.32Å; Q414-C417 WeakPolarHBondContact O-CA 3.35Å; Q414-C417 WeakPolarHBondContact O-CB 3.29Å; Q414-C417 PolarHBondContact O-N 2.97Å; Q414-G418 CarbonylContact C-O 3.41Å; Q414-G418 CarbonylContact O-C 3.39Å; Q414-G418 PolarHBondContact O-N 3.43Å; Q414-Q420 VanDerWaalsContact OE1-OE1 3.1Å
415	N	55.6	Low	67.3	Low	40 Å²	40	40.5 Å²	40.5	21%	0.214	21%	0.208	C	C	.	.	H	α-helix	trans	-61	-25.1	177.3	-67.3	-36.1	0	0	0	113.2	R408 A411 W412 L419	R408-N415 PolarHBondContact O-ND2 3.48Å; A411-N415 PolarHBondContact O-N 3.33Å; A411-N415 PolarHBondContact O-ND2 3.31Å; W412-N415 PolarHBondContact O-N 2.91Å; N415-L419 HydrophobicContact CB-CG 4.31Å
416	L	59.5	Low	67.6	Low	57 Å²	57	39.9 Å²	39.9	30%	0.298	21%	0.206	S	C	.	.	H	α-helix	trans	-71.3	-35.9	169.7	-92.6	142.5	0	0	0	112.5	D38 W412 T413 Q414	D38-L416 VanDerWaalsContact C-CD2 3.43Å; D38-L416 HydrophobicContact CB-CD1 3.9Å; D38-L416 HydrophobicContact CB-CD2 3.96Å; D38-L416 WeakPolarHBondContact O-CD2 3.4Å; W412-L416 HydrophobicContact CD2-CD1 3.91Å; W412-L416 HydrophobicContact CE3-CD1 3.71Å; W412-L416 HydrophobicContact CH2-CD1 3.87Å; W412-L416 HydrophobicContact CZ2-CD1 4.03Å; W412-L416 HydrophobicContact CZ3-CD1 3.69Å; W412-L416 WeakPolarHBondContact O-CD1 3.38Å; W412-L416 PolarHBondContact O-N 2.9Å; T413-L416 VanDerWaalsContact O-CB 3.29Å; T413-L416 WeakPolarHBondContact O-CB 3.39Å; T413-L416 PolarHBondContact O-N 2.9Å; Q414-L416 PolarHBondContact O-N 3.3Å; Q414-L416 VanDerWaalsContact O-N 3.13Å
417	C	56.1	Low	67.8	Low	8 Å²	8	41.4 Å²	41.4	5%	0.054	22%	0.222	C	C	.	.	H	α-helix	trans	-80	-20.5	174.4	-71.6	0	0	0	0	114.8	C40 I389 T413 Q414	C40-C417 WeakPolarHBondContact CA-SG 3.35Å; C40-C417 VanDerWaalsContact CB-CA 3.44Å; C40-C417 HydrophobicContact CB-CB 3.72Å; C40-C417 WeakPolarHBondContact CB-SG 3.43Å; C40-C417 WeakPolarHBondContact SG-CA 3.45Å; C40-C417 WeakPolarHBondContact SG-CB 3.41Å; C40-C417 CovalentContact SG-SG 2Å; C40-C417 PolarHBondContact SG-SG 3.23Å; I389-C417 HydrophobicContact CD1-CB 3.96Å; T413-C417 PolarHBondContact O-N 3.47Å; Q414-C417 CarbonylContact O-C 3.43Å; Q414-C417 VanDerWaalsContact O-CA 3.32Å; Q414-C417 WeakPolarHBondContact O-CA 3.35Å; Q414-C417 WeakPolarHBondContact O-CB 3.29Å; Q414-C417 PolarHBondContact O-N 2.97Å
418	G	57.7	Low	68.4	Low	38 Å²	38	42.1 Å²	42.1	39%	0.392	23%	0.225	S	C	.	.			trans	154.7	132.8	-179.8	0	0	0	0	0	109.3	Q414 Q420	Q414-G418 CarbonylContact C-O 3.41Å; Q414-G418 CarbonylContact O-C 3.39Å; Q414-G418 PolarHBondContact O-N 3.43Å; G418-Q420 PolarHBondContact O-N 2.93Å
419	L	56.8	Low	69.4	Low	62 Å²	62	38.2 Å²	38.2	33%	0.325	21%	0.211	S	C	.	.			trans	-63.7	105.5	178.5	-108	111.1	0	0	0	110.3	P407 N415 F421	P407-L419 HydrophobicContact CB-CD2 3.71Å; N415-L419 HydrophobicContact CB-CG 4.31Å; L419-F421 HydrophobicContact CB-CE2 3.77Å; L419-F421 HydrophobicContact CB-CZ 3.93Å; L419-F421 HydrophobicContact CD2-CE1 3.94Å; L419-F421 HydrophobicContact CD2-CE2 4.27Å; L419-F421 HydrophobicContact CD2-CZ 3.56Å; L419-F421 HydrophobicContact CG-CZ 4.39Å; L419-F421 VanDerWaalsContact O-CD2 3.26Å; L419-F421 WeakPolarHBondContact O-CD2 3.5Å; L419-F421 WeakPolarHBondContact O-CE2 3.34Å
420	Q	64.3	Low	70.6	Confident	59 Å²	59	34.2 Å²	34.2	28%	0.276	19%	0.194	S	C	.	.			trans	-82.3	127.3	173.6	-68.3	-173.4	3.2	0	0	109.4	R408 Q414 G418	R408-Q420 PolarHBondContact N-O 3.42Å; Q414-Q420 VanDerWaalsContact OE1-OE1 3.1Å; G418-Q420 PolarHBondContact O-N 2.93Å
421	F	69.3	Low	72.2	Confident	35 Å²	35	32.2 Å²	32.2	15%	0.154	18%	0.179	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-108.2	135.1	179	-65.3	-84	0	0	0	110.5	D309 W313 R405 P407 L419 I423	D309-F421 HydrophobicContact CB-CE2 4.02Å; D309-F421 HydrophobicContact CB-CZ 4.06Å; D309-F421 WeakPolarHBondContact O-CZ 3.41Å; W313-F421 HydrophobicContact CB-CE1 3.88Å; W313-F421 HydrophobicContact CG-CE1 4.02Å; R405-F421 HydrophobicContact CB-CB 4.23Å; R405-F421 HydrophobicContact CB-CD1 3.79Å; R405-F421 HydrophobicContact CB-CE1 4.47Å; R405-F421 HydrophobicContact CB-CG 4.16Å; P407-F421 HydrophobicContact CB-CD1 4.21Å; P407-F421 HydrophobicContact CB-CE1 4.02Å; L419-F421 HydrophobicContact CB-CE2 3.77Å; L419-F421 HydrophobicContact CB-CZ 3.93Å; L419-F421 HydrophobicContact CD2-CE1 3.94Å; L419-F421 HydrophobicContact CD2-CE2 4.27Å; L419-F421 HydrophobicContact CD2-CZ 3.56Å; L419-F421 HydrophobicContact CG-CZ 4.39Å; L419-F421 VanDerWaalsContact O-CD2 3.26Å; L419-F421 WeakPolarHBondContact O-CD2 3.5Å; L419-F421 WeakPolarHBondContact O-CE2 3.34Å; F421-I423 HydrophobicContact CB-CG1 4.42Å
422	S	75.1	Confident	74	Confident	17 Å²	17	32.2 Å²	32.2	12%	0.119	18%	0.179	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-76.5	132.6	156.4	-73.3	0	0	0	0	108.4	N169 R405 V406	N169-S422 WeakPolarHBondContact ND2-CB 3.16Å; N169-S422 PolarHBondContact ND2-OG 3.49Å; R405-S422 WeakPolarHBondContact CA-O 3.37Å; V406-S422 PolarHBondContact N-O 3.47Å; V406-S422 PolarHBondContact O-N 3.43Å
423	I	81.9	Confident	75.8	Confident	87 Å²	87	25.1 Å²	25.1	45%	0.446	15%	0.152	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-115	136.3	-172.2	-56.5	176.9	0	0	0	109	V403 M404 F421	V403-I423 HydrophobicContact CB-CG2 3.53Å; V403-I423 HydrophobicContact CG1-CG2 3.69Å; V403-I423 HydrophobicContact CG2-CG2 3.79Å; M404-I423 WeakPolarHBondContact O-CA 3.38Å; F421-I423 HydrophobicContact CB-CG1 4.42Å
424	L	85.8	Confident	77.8	Confident	8 Å²	8	25.2 Å²	25.2	4%	0.042	15%	0.152	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-133.9	131.6	169.2	-177.1	65.3	0	0	0	109.4	L173 A177 V403 M404 D428 I429 L465	L173-L424 HydrophobicContact CD1-CB 3.86Å; L173-L424 HydrophobicContact CD1-CD2 4.28Å; L173-L424 HydrophobicContact CD2-CB 3.94Å; L173-L424 HydrophobicContact CG-CB 4.05Å; L173-L424 HydrophobicContact CG-CD2 4.19Å; A177-L424 HydrophobicContact CB-CD2 3.77Å; V403-L424 CarbonylContact C-O 3.53Å; V403-L424 WeakPolarHBondContact CA-O 3.25Å; M404-L424 HydrophobicContact CB-CB 4.49Å; M404-L424 PolarHBondContact N-O 3.42Å; M404-L424 PolarHBondContact O-N 3.43Å; M404-L424 VanDerWaalsContact O-N 3.09Å; L424-D428 HydrophobicContact CD1-CB 4.07Å; L424-I429 HydrophobicContact CD2-CD1 3.99Å; L424-I429 HydrophobicContact CD2-CG1 4.04Å; L424-I429 HydrophobicContact CG-CG1 4.48Å; L424-L465 HydrophobicContact CD1-CD1 4.08Å
425	G	89.2	Confident	79.7	Confident	16 Å²	16	24.8 Å²	24.8	17%	0.165	15%	0.15	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-70.5	142.8	-179	0	0	0	0	0	112.5	G427 D428	G425-G427 PolarHBondContact O-N 3.02Å; G425-D428 WeakPolarHBondContact CA-OD2 3.13Å; G425-D428 PolarHBondContact N-OD2 3.39Å; G425-D428 PolarHBondContact O-N 2.9Å; G425-D428 VanDerWaalsContact O-N 3.16Å
426	Y	89.8	Confident	81.6	Confident	3 Å²	3	22.9 Å²	22.9	1%	0.012	14%	0.14	C	C	.	.	H	α-helix	trans	-61.8	-31	169.4	-62.3	-26.8	0	0	0	111.7	F251 Q316 G320 F323 P401 V402 V403 M404 D428 I429 I430	F251-Y426 HydrophobicContact CE2-CD2 4.47Å; F251-Y426 AromaticContact CE2-CE2 3.62Å; F251-Y426 HydrophobicContact CE2-CE2 3.62Å; F251-Y426 HydrophobicContact CZ-CE2 4.07Å; Q316-Y426 PolarHBondContact O-OH 3.33Å; G320-Y426 WeakPolarHBondContact CA-OH 3.18Å; F323-Y426 HydrophobicContact CD1-CD2 4.19Å; F323-Y426 HydrophobicContact CE1-CD2 4.42Å; P401-Y426 WeakPolarHBondContact O-CE2 3.44Å; P401-Y426 PolarHBondContact O-OH 3.25Å; V402-Y426 HydrophobicContact CB-CD2 4.5Å; V402-Y426 HydrophobicContact CG1-CD2 4.34Å; V402-Y426 WeakPolarHBondContact O-CD2 2.98Å; V402-Y426 PolarHBondContact O-N 3.39Å; V403-Y426 VanDerWaalsContact C-CE1 3.41Å; V403-Y426 PolarHBondContact O-OH 2.93Å; M404-Y426 HydrophobicContact CB-CE1 4.43Å; M404-Y426 HydrophobicContact CE-CD1 4.49Å; M404-Y426 HydrophobicContact CE-CE1 4.43Å; M404-Y426 HydrophobicContact CG-CD1 3.93Å; M404-Y426 HydrophobicContact CG-CE1 3.54Å; Y426-D428 VanDerWaalsContact C-N 3.28Å; Y426-D428 PolarHBondContact O-N 2.97Å; Y426-I429 PolarHBondContact O-N 3.3Å; Y426-I430 VanDerWaalsContact O-CB 3.29Å; Y426-I430 WeakPolarHBondContact O-CB 3.26Å; Y426-I430 VanDerWaalsContact O-CG1 3.3Å; Y426-I430 WeakPolarHBondContact O-CG1 3.42Å; Y426-I430 PolarHBondContact O-N 3.22Å
427	G	88.6	Confident	83.2	Confident	33 Å²	33	20.2 Å²	20.2	34%	0.34	13%	0.126	S	C	.	.	H	α-helix	trans	-57	-40.4	173.3	0	0	0	0	0	112.7	G425 I429 I430 V431	G425-G427 PolarHBondContact O-N 3.02Å; G427-I429 PolarHBondContact O-N 3.17Å; G427-I430 PolarHBondContact O-N 3.47Å; G427-V431 WeakPolarHBondContact O-CB 3.33Å; G427-V431 WeakPolarHBondContact O-CG2 3.47Å; G427-V431 PolarHBondContact O-N 3.2Å
428	D	90.7	Very high	85	Confident	23 Å²	23	19.8 Å²	19.8	12%	0.123	12%	0.123	C	C	.	.	H	α-helix	trans	-70.5	-19.5	-178.8	-52.7	-41.5	0	0	0	113	L424 G425 Y426 P432 Y461 A481 L485	L424-D428 HydrophobicContact CD1-CB 4.07Å; G425-D428 WeakPolarHBondContact CA-OD2 3.13Å; G425-D428 PolarHBondContact N-OD2 3.39Å; G425-D428 PolarHBondContact O-N 2.9Å; G425-D428 VanDerWaalsContact O-N 3.16Å; Y426-D428 VanDerWaalsContact C-N 3.28Å; Y426-D428 PolarHBondContact O-N 2.97Å; D428-P432 VanDerWaalsContact O-CD 3.26Å; D428-P432 WeakPolarHBondContact O-CD 3.16Å; D428-P432 WeakPolarHBondContact O-CG 3.34Å; D428-Y461 WeakPolarHBondContact O-CE2 3.4Å; D428-Y461 PolarHBondContact O-OH 3.48Å; D428-A481 HydrophobicContact CB-CB 4.23Å; D428-L485 HydrophobicContact CB-CD1 4.06Å
429	I	93.8	Very high	86.7	Confident	0 Å²	0	18 Å²	18	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-91.8	-50.9	175.4	-61.7	175.1	0	0	0	109.6	A177 T180 V181 C324 M404 L424 Y426 G427 G433	A177-I429 HydrophobicContact CB-CD1 4.37Å; A177-I429 HydrophobicContact CB-CG1 4.37Å; T180-I429 HydrophobicContact CG2-CG2 3.94Å; V181-I429 HydrophobicContact CG2-CG2 3.77Å; C324-I429 HydrophobicContact CB-CG2 4.39Å; M404-I429 HydrophobicContact CE-CD1 3.38Å; M404-I429 HydrophobicContact CG-CD1 4.22Å; M404-I429 HydrophobicContact SD-CD1 3.37Å; M404-I429 WeakPolarHBondContact SD-CD1 3.31Å; L424-I429 HydrophobicContact CD2-CD1 3.99Å; L424-I429 HydrophobicContact CD2-CG1 4.04Å; L424-I429 HydrophobicContact CG-CG1 4.48Å; Y426-I429 PolarHBondContact O-N 3.3Å; G427-I429 PolarHBondContact O-N 3.17Å; I429-G433 WeakPolarHBondContact O-CA 3.37Å; I429-G433 PolarHBondContact O-N 3.42Å
430	I	92.7	Very high	88.3	Confident	11 Å²	11	15 Å²	15	6%	0.056	9%	0.089	C	C	.	.	H	α-helix	trans	-66.3	-48.6	-174.2	-73.4	171.7	0	0	0	111.1	F323 C324 F327 Y426 G427 G433 L434	F323-I430 HydrophobicContact CD1-CD1 4.06Å; F323-I430 HydrophobicContact CE1-CD1 3.63Å; C324-I430 HydrophobicContact CB-CD1 4.48Å; C324-I430 HydrophobicContact CB-CG1 4.08Å; F327-I430 HydrophobicContact CB-CD1 4.24Å; F327-I430 HydrophobicContact CD1-CB 4.39Å; F327-I430 HydrophobicContact CD1-CD1 4.25Å; F327-I430 HydrophobicContact CD1-CG1 4.38Å; F327-I430 HydrophobicContact CD1-CG2 3.18Å; F327-I430 HydrophobicContact CE1-CG2 3.19Å; F327-I430 HydrophobicContact CG-CD1 4.14Å; F327-I430 HydrophobicContact CG-CG2 4.12Å; F327-I430 HydrophobicContact CZ-CG2 4.17Å; Y426-I430 VanDerWaalsContact O-CB 3.29Å; Y426-I430 WeakPolarHBondContact O-CB 3.26Å; Y426-I430 VanDerWaalsContact O-CG1 3.3Å; Y426-I430 WeakPolarHBondContact O-CG1 3.42Å; Y426-I430 PolarHBondContact O-N 3.22Å; G427-I430 PolarHBondContact O-N 3.47Å; I430-G433 CarbonylContact O-C 3.49Å; I430-G433 WeakPolarHBondContact O-CA 3.38Å; I430-G433 PolarHBondContact O-N 3.41Å; I430-G433 VanDerWaalsContact O-N 3.11Å; I430-L434 HydrophobicContact CG2-CG 4.49Å; I430-L434 WeakPolarHBondContact O-CG 3.43Å; I430-L434 PolarHBondContact O-N 2.98Å
431	V	91.3	Very high	89.5	Confident	16 Å²	16	12.7 Å²	12.7	10%	0.097	8%	0.078	C	C	.	.	H	α-helix	trans	-65	-52.9	-169.4	170.8	0	0	0	0	111.5	L343 L346 G427 G433 L434 L482	L343-V431 HydrophobicContact CD1-CG1 4.44Å; L343-V431 HydrophobicContact CG-CG1 4.06Å; L346-V431 HydrophobicContact CB-CG1 4.39Å; L346-V431 HydrophobicContact CD1-CB 4.16Å; L346-V431 HydrophobicContact CD1-CG1 3.48Å; L346-V431 VanDerWaalsContact CD1-CG1 3.48Å; L346-V431 HydrophobicContact CD1-CG2 3.56Å; G427-V431 WeakPolarHBondContact O-CB 3.33Å; G427-V431 WeakPolarHBondContact O-CG2 3.47Å; G427-V431 PolarHBondContact O-N 3.2Å; V431-G433 VanDerWaalsContact C-N 3.28Å; V431-G433 PolarHBondContact O-N 3.32Å; V431-L434 PolarHBondContact O-N 3.4Å; V431-L482 HydrophobicContact CB-CD2 4.31Å; V431-L482 HydrophobicContact CG1-CD2 4.3Å
432	P	93.9	Very high	90.5	Very high	0 Å²	0	11.1 Å²	11.1	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-67.2	-30	170.5	-19.4	34.8	0	0	0	112.5	D428 L434 L435 V436 Y461 L482 L485 T489	D428-P432 VanDerWaalsContact O-CD 3.26Å; D428-P432 WeakPolarHBondContact O-CD 3.16Å; D428-P432 WeakPolarHBondContact O-CG 3.34Å; P432-L434 VanDerWaalsContact C-N 3.31Å; P432-L434 PolarHBondContact O-N 2.77Å; P432-L435 WeakPolarHBondContact O-CB 3.49Å; P432-L435 PolarHBondContact O-N 3.42Å; P432-L435 VanDerWaalsContact O-N 3.13Å; P432-V436 PolarHBondContact O-N 2.97Å; P432-V436 VanDerWaalsContact O-N 3.07Å; P432-Y461 HydrophobicContact CB-CD2 3.64Å; P432-Y461 HydrophobicContact CB-CE2 3.85Å; P432-Y461 HydrophobicContact CG-CD2 4.22Å; P432-Y461 HydrophobicContact CG-CE2 4.03Å; P432-L482 HydrophobicContact CG-CD2 4.16Å; P432-L485 HydrophobicContact CG-CB 3.9Å; P432-L485 HydrophobicContact CG-CD1 4.22Å; P432-T489 HydrophobicContact CB-CG2 4.36Å
433	G	94.6	Very high	91.2	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-61.2	-33.3	176.7	0	0	0	0	0	114	I429 I430 V431 L435 V436 A437	I429-G433 WeakPolarHBondContact O-CA 3.37Å; I429-G433 PolarHBondContact O-N 3.42Å; I430-G433 CarbonylContact O-C 3.49Å; I430-G433 WeakPolarHBondContact O-CA 3.38Å; I430-G433 PolarHBondContact O-N 3.41Å; I430-G433 VanDerWaalsContact O-N 3.11Å; V431-G433 VanDerWaalsContact C-N 3.28Å; V431-G433 PolarHBondContact O-N 3.32Å; G433-L435 VanDerWaalsContact C-N 3.33Å; G433-L435 PolarHBondContact O-N 2.93Å; G433-V436 PolarHBondContact O-N 3.26Å; G433-A437 WeakPolarHBondContact O-CB 3.35Å; G433-A437 PolarHBondContact O-N 3.48Å
434	L	92.9	Very high	91.5	Very high	8 Å²	8	7.5 Å²	7.5	4%	0.042	5%	0.051	C	C	.	.	H	α-helix	trans	-63.6	-37.8	173.2	-69.7	176.2	0	0	0	112.2	F327 I331 L333 L342 I430 V431 P432 A437 Y438	F327-L434 HydrophobicContact CD1-CD2 4.48Å; F327-L434 HydrophobicContact CE1-CD1 4.34Å; I331-L434 HydrophobicContact CB-CD2 3.73Å; I331-L434 HydrophobicContact CG2-CD1 4.06Å; I331-L434 HydrophobicContact CG2-CD2 3.73Å; L333-L434 HydrophobicContact CD1-CB 3.86Å; L342-L434 HydrophobicContact CD2-CD1 4.07Å; I430-L434 HydrophobicContact CG2-CG 4.49Å; I430-L434 WeakPolarHBondContact O-CG 3.43Å; I430-L434 PolarHBondContact O-N 2.98Å; V431-L434 PolarHBondContact O-N 3.4Å; P432-L434 VanDerWaalsContact C-N 3.31Å; P432-L434 PolarHBondContact O-N 2.77Å; L434-A437 PolarHBondContact O-N 3.07Å; L434-Y438 PolarHBondContact O-N 3.05Å
435	L	94.8	Very high	91.4	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-68.3	-41.4	173.9	175.2	61.6	0	0	0	111.1	F336 C339 L343 P432 G433 A437 Y438 C439 L490	F336-L435 HydrophobicContact CD2-CD1 3.9Å; F336-L435 HydrophobicContact CE2-CD1 3.77Å; C339-L435 HydrophobicContact CB-CD1 3.93Å; L343-L435 HydrophobicContact CD2-CB 4.29Å; L343-L435 HydrophobicContact CD2-CD2 3.95Å; P432-L435 WeakPolarHBondContact O-CB 3.49Å; P432-L435 PolarHBondContact O-N 3.42Å; P432-L435 VanDerWaalsContact O-N 3.13Å; G433-L435 VanDerWaalsContact C-N 3.33Å; G433-L435 PolarHBondContact O-N 2.93Å; L435-A437 VanDerWaalsContact C-N 3.3Å; L435-A437 PolarHBondContact O-N 3.38Å; L435-Y438 HydrophobicContact CD1-CD1 4.39Å; L435-Y438 WeakPolarHBondContact O-CB 3.32Å; L435-Y438 PolarHBondContact O-N 3Å; L435-C439 PolarHBondContact O-N 3.05Å; L435-C439 PolarHBondContact O-SG 3.43Å; L435-C439 VanDerWaalsContact O-SG 3.41Å; L435-L490 HydrophobicContact CD2-CD2 3.77Å; L435-L490 HydrophobicContact CD2-CG 4.27Å
436	V	95.4	Very high	91.2	Very high	0 Å²	0	11.4 Å²	11.4	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-59.9	-42.7	173.6	172.8	0	0	0	0	111	V181 P432 G433 C439 S440 F454 C457 V458	V181-V436 HydrophobicContact CG1-CB 3.9Å; V181-V436 HydrophobicContact CG1-CG1 3.9Å; V181-V436 HydrophobicContact CG1-CG2 3.69Å; P432-V436 PolarHBondContact O-N 2.97Å; P432-V436 VanDerWaalsContact O-N 3.07Å; G433-V436 PolarHBondContact O-N 3.26Å; V436-C439 PolarHBondContact O-N 2.91Å; V436-S440 WeakPolarHBondContact O-CB 3.22Å; V436-S440 PolarHBondContact O-N 3.26Å; V436-F454 HydrophobicContact CG1-CD2 3.79Å; V436-F454 HydrophobicContact CG1-CE2 3.66Å; V436-C457 HydrophobicContact CG2-CB 4.18Å; V436-C457 VanDerWaalsContact CG2-SG 3.54Å; V436-V458 HydrophobicContact CG1-CG2 3.63Å
437	A	93.3	Very high	90.8	Very high	0 Å²	0	17.7 Å²	17.7	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-62.1	-43.1	175.3	0	0	0	0	0	111.5	G433 L434 L435 S440 R441	G433-A437 WeakPolarHBondContact O-CB 3.35Å; G433-A437 PolarHBondContact O-N 3.48Å; L434-A437 PolarHBondContact O-N 3.07Å; L435-A437 VanDerWaalsContact C-N 3.3Å; L435-A437 PolarHBondContact O-N 3.38Å; A437-S440 PolarHBondContact O-N 3.43Å; A437-S440 PolarHBondContact O-OG 3.23Å; A437-R441 WeakPolarHBondContact O-CG 3.14Å; A437-R441 PolarHBondContact O-N 3.31Å; A437-R441 VanDerWaalsContact O-N 3.15Å
438	Y	92.4	Very high	90.4	Very high	0 Å²	0	16.6 Å²	16.6	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-59.5	-49.7	173.2	175.5	-103.1	0	0	0	112.1	L333 S334 F336 L434 L435 S440 R441 F442 W445 F506	L333-Y438 WeakPolarHBondContact O-CD2 3.49Å; S334-Y438 WeakPolarHBondContact O-CE2 3.19Å; F336-Y438 HydrophobicContact CB-CE1 3.77Å; F336-Y438 HydrophobicContact CD2-CE1 4.29Å; F336-Y438 PolarHBondContact N-OH 2.63Å; L434-Y438 PolarHBondContact O-N 3.05Å; L435-Y438 HydrophobicContact CD1-CD1 4.39Å; L435-Y438 WeakPolarHBondContact O-CB 3.32Å; L435-Y438 PolarHBondContact O-N 3Å; Y438-S440 VanDerWaalsContact C-N 3.26Å; Y438-S440 PolarHBondContact O-N 3.03Å; Y438-R441 PolarHBondContact O-N 3.11Å; Y438-R441 VanDerWaalsContact O-N 3.09Å; Y438-F442 PolarHBondContact O-N 3.08Å; Y438-W445 HydrophobicContact CE2-CH2 4.22Å; Y438-W445 AromaticContact CE2-CZ3 3.88Å; Y438-W445 HydrophobicContact CE2-CZ3 3.88Å; Y438-F506 HydrophobicContact CD1-CE2 4.04Å; Y438-F506 HydrophobicContact CD1-CZ 4.22Å; Y438-F506 AromaticContact CE1-CD2 3.9Å; Y438-F506 HydrophobicContact CE1-CD2 3.9Å; Y438-F506 AromaticContact CE1-CE2 3.43Å; Y438-F506 HydrophobicContact CE1-CE2 3.43Å; Y438-F506 VanDerWaalsContact CE1-CE2 3.43Å; Y438-F506 AromaticContact CE1-CZ 3.81Å; Y438-F506 HydrophobicContact CE1-CZ 3.81Å; Y438-F506 PolarHBondContact OH-O 3.36Å
439	C	93.2	Very high	89.6	Confident	0 Å²	0	26.8 Å²	26.8	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-56.6	-39.1	176.6	-74.8	0	0	0	0	112.4	L435 V436 F442 D443 C457	L435-C439 PolarHBondContact O-N 3.05Å; L435-C439 PolarHBondContact O-SG 3.43Å; L435-C439 VanDerWaalsContact O-SG 3.41Å; V436-C439 PolarHBondContact O-N 2.91Å; C439-F442 PolarHBondContact O-N 3.39Å; C439-D443 PolarHBondContact O-N 3.05Å; C439-C457 HydrophobicContact CB-CB 4.26Å
440	S	91.9	Very high	89	Confident	0 Å²	0	34.9 Å²	34.9	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-66.8	-34	177.4	80.3	0	0	0	0	114.1	G185 R189 V436 A437 Y438	G185-S440 PolarHBondContact O-OG 3.43Å; R189-S440 PolarHBondContact NE-O 3.12Å; V436-S440 WeakPolarHBondContact O-CB 3.22Å; V436-S440 PolarHBondContact O-N 3.26Å; A437-S440 PolarHBondContact O-N 3.43Å; A437-S440 PolarHBondContact O-OG 3.23Å; Y438-S440 VanDerWaalsContact C-N 3.26Å; Y438-S440 PolarHBondContact O-N 3.03Å
441	R	88.7	Confident	88.8	Confident	9 Å²	9	36.3 Å²	36.3	3%	0.034	17%	0.165	C	C	.	.	H	α-helix	trans	-74.1	-44.8	174.5	-67.4	179.3	-171	136	4	110.5	S188 E192 T332 A437 Y438 D443 I444 W445	S188-R441 PolarHBondContact OG-NE 2.6Å; S188-R441 PolarHBondContact OG-NH2 2.89Å; E192-R441 HydrophobicContact CB-CG 4.15Å; E192-R441 HydrophobicContact CG-CB 4.42Å; E192-R441 HydrophobicContact CG-CG 4.18Å; T332-R441 VanDerWaalsContact CA-NH1 3.33Å; A437-R441 WeakPolarHBondContact O-CG 3.14Å; A437-R441 PolarHBondContact O-N 3.31Å; A437-R441 VanDerWaalsContact O-N 3.15Å; Y438-R441 PolarHBondContact O-N 3.11Å; Y438-R441 VanDerWaalsContact O-N 3.09Å; R441-D443 VanDerWaalsContact C-N 3.27Å; R441-D443 PolarHBondContact O-N 3.06Å; R441-I444 WeakPolarHBondContact O-CA 3.3Å; R441-I444 WeakPolarHBondContact O-CB 3.35Å; R441-I444 PolarHBondContact O-N 3.36Å; R441-W445 HydrophobicContact CB-CH2 4.44Å; R441-W445 HydrophobicContact CB-CZ2 4.08Å; R441-W445 PolarHBondContact O-N 2.94Å; R441-W445 VanDerWaalsContact O-N 3.09Å
442	F	89.6	Confident	88.8	Confident	2 Å²	2	38 Å²	38	1%	0.009	18%	0.175	C	C	.	.	H	α-helix	trans	-58.4	-39.1	177	-169.6	-96.1	0	0	0	112.3	Y438 C439 I444 W445 V446 Y453 Q505 F506	Y438-F442 PolarHBondContact O-N 3.08Å; C439-F442 PolarHBondContact O-N 3.39Å; F442-I444 PolarHBondContact O-N 3.01Å; F442-W445 HydrophobicContact CB-CE3 4.21Å; F442-W445 AromaticContact CD2-CE3 3.74Å; F442-W445 HydrophobicContact CD2-CE3 3.74Å; F442-W445 HydrophobicContact CD2-CZ3 4.22Å; F442-W445 HydrophobicContact CG-CE3 4.41Å; F442-W445 PolarHBondContact O-N 3.09Å; F442-W445 VanDerWaalsContact O-N 3.09Å; F442-V446 HydrophobicContact CD1-CG2 3.96Å; F442-V446 HydrophobicContact CE1-CB 4.42Å; F442-V446 HydrophobicContact CE1-CG2 3.41Å; F442-V446 VanDerWaalsContact CE1-CG2 3.41Å; F442-V446 HydrophobicContact CE2-CG2 4.06Å; F442-V446 HydrophobicContact CZ-CG2 3.45Å; F442-V446 VanDerWaalsContact CZ-CG2 3.45Å; F442-V446 PolarHBondContact O-N 3.21Å; F442-Y453 HydrophobicContact CD1-CD1 4.32Å; F442-Y453 AromaticContact CD1-CD2 3.88Å; F442-Y453 HydrophobicContact CD1-CD2 3.88Å; F442-Y453 HydrophobicContact CD1-CE1 4.25Å; F442-Y453 AromaticContact CD1-CE2 3.81Å; F442-Y453 HydrophobicContact CD1-CE2 3.81Å; F442-Y453 HydrophobicContact CD1-CG 4.14Å; F442-Y453 HydrophobicContact CE1-CD2 4.26Å; F442-Y453 HydrophobicContact CE1-CE1 4.19Å; F442-Y453 AromaticContact CE1-CE2 3.71Å; F442-Y453 HydrophobicContact CE1-CE2 3.71Å; F442-Y453 AromaticContact CE1-CZ 3.66Å; F442-Q505 HydrophobicContact CZ-CB 4.48Å; F442-F506 HydrophobicContact CB-CD2 4.5Å; F442-F506 HydrophobicContact CB-CE2 4.37Å; F442-F506 AromaticContact CD1-CD2 3.63Å; F442-F506 HydrophobicContact CD1-CD2 3.63Å; F442-F506 HydrophobicContact CD1-CE2 4.02Å; F442-F506 AromaticContact CD2-CD2 3.8Å; F442-F506 HydrophobicContact CD2-CD2 3.8Å; F442-F506 HydrophobicContact CD2-CE2 4.45Å; F442-F506 HydrophobicContact CE1-CB 4.38Å; F442-F506 AromaticContact CE1-CD2 3.67Å; F442-F506 HydrophobicContact CE1-CD2 3.67Å; F442-F506 HydrophobicContact CE1-CE2 4.46Å; F442-F506 HydrophobicContact CE1-CG 4.47Å; F442-F506 HydrophobicContact CE2-CB 4.18Å; F442-F506 AromaticContact CE2-CD2 3.87Å; F442-F506 HydrophobicContact CE2-CD2 3.87Å; F442-F506 AromaticContact CG-CD2 3.7Å; F442-F506 HydrophobicContact CG-CD2 3.7Å; F442-F506 HydrophobicContact CG-CE2 4.02Å; F442-F506 HydrophobicContact CZ-CB 3.9Å; F442-F506 AromaticContact CZ-CD2 3.8Å; F442-F506 HydrophobicContact CZ-CD2 3.8Å; F442-F506 HydrophobicContact CZ-CG 4.36Å
443	D	90.8	Very high	88.7	Confident	1 Å²	1	38.1 Å²	38.1	1%	0.005	18%	0.176	C	C	.	.	H	α-helix	trans	-58.7	-30.7	172.7	-92.3	-43.6	0	0	0	113.1	C439 R441 N447 S448 N451 V452 Y453 F454	C439-D443 PolarHBondContact O-N 3.05Å; R441-D443 VanDerWaalsContact C-N 3.27Å; R441-D443 PolarHBondContact O-N 3.06Å; D443-N447 PolarHBondContact O-N 3.48Å; D443-S448 WeakPolarHBondContact O-CB 3.23Å; D443-S448 PolarHBondContact O-N 3.15Å; D443-S448 WeakPolarHBondContact OD1-CB 3.47Å; D443-S448 PolarHBondContact OD1-OG 2.89Å; D443-N451 VanDerWaalsContact CG-CA 3.47Å; D443-N451 WeakPolarHBondContact OD2-CA 3.48Å; D443-V452 PolarHBondContact OD1-N 3.39Å; D443-V452 PolarHBondContact OD2-N 2.9Å; D443-Y453 WeakPolarHBondContact OD1-CD2 3.44Å; D443-Y453 PolarHBondContact OD1-N 3.45Å; D443-Y453 PolarHBondContact OD2-N 3.33Å; D443-Y453 VanDerWaalsContact OD2-N 3.16Å; D443-F454 WeakPolarHBondContact OD2-CB 3.32Å; D443-F454 PolarHBondContact OD2-N 3.38Å
444	I	87.9	Confident	88.7	Confident	27 Å²	27	39 Å²	39	14%	0.138	18%	0.18	C	C	.	.	H	α-helix	trans	-73.6	-46.7	172	-63	173.9	0	0	0	110.3	R189 E192 R193 L196 R441 F442 V446 N447	R189-I444 HydrophobicContact CB-CD1 4.4Å; R189-I444 HydrophobicContact CG-CD1 3.29Å; R189-I444 HydrophobicContact CG-CG1 3.89Å; R189-I444 VanDerWaalsContact O-CD1 3.3Å; R189-I444 WeakPolarHBondContact O-CD1 3.33Å; E192-I444 HydrophobicContact CB-CD1 4.42Å; R193-I444 HydrophobicContact CB-CD1 4.16Å; L196-I444 HydrophobicContact CD1-CG2 3.49Å; L196-I444 VanDerWaalsContact CD1-CG2 3.49Å; R441-I444 WeakPolarHBondContact O-CA 3.3Å; R441-I444 WeakPolarHBondContact O-CB 3.35Å; R441-I444 PolarHBondContact O-N 3.36Å; F442-I444 PolarHBondContact O-N 3.01Å; I444-V446 VanDerWaalsContact C-N 3.26Å; I444-V446 PolarHBondContact O-N 3.01Å; I444-N447 WeakPolarHBondContact O-CA 3.27Å; I444-N447 PolarHBondContact O-N 2.65Å
445	W	84.7	Confident	88.7	Confident	67 Å²	67	43.3 Å²	43.3	25%	0.254	20%	0.202	S	C	.	.	H	α-helix	trans	-60.3	-37.1	-176.7	-59.3	-26.1	0	0	0	112.5	E192 Y438 R441 F442 N447 T510	E192-W445 PolarHBondContact OE1-NE1 3.02Å; Y438-W445 HydrophobicContact CE2-CH2 4.22Å; Y438-W445 AromaticContact CE2-CZ3 3.88Å; Y438-W445 HydrophobicContact CE2-CZ3 3.88Å; R441-W445 HydrophobicContact CB-CH2 4.44Å; R441-W445 HydrophobicContact CB-CZ2 4.08Å; R441-W445 PolarHBondContact O-N 2.94Å; R441-W445 VanDerWaalsContact O-N 3.09Å; F442-W445 HydrophobicContact CB-CE3 4.21Å; F442-W445 AromaticContact CD2-CE3 3.74Å; F442-W445 HydrophobicContact CD2-CE3 3.74Å; F442-W445 HydrophobicContact CD2-CZ3 4.22Å; F442-W445 HydrophobicContact CG-CE3 4.41Å; F442-W445 PolarHBondContact O-N 3.09Å; F442-W445 VanDerWaalsContact O-N 3.09Å; W445-N447 VanDerWaalsContact C-N 3.3Å; W445-T510 HydrophobicContact CB-CG2 3.97Å; W445-T510 HydrophobicContact CD2-CG2 3.8Å; W445-T510 HydrophobicContact CE3-CG2 3.55Å; W445-T510 HydrophobicContact CG-CG2 4.02Å; W445-T510 HydrophobicContact CZ3-CG2 4.25Å
446	V	84.7	Confident	88.7	Confident	40 Å²	40	44.8 Å²	44.8	24%	0.242	21%	0.212	C	C	.	.	T	Hydrogen-bonded Turn	trans	-87.5	1.8	175.6	-178.1	0	0	0	0	112.5	F442 I444 S448	F442-V446 HydrophobicContact CD1-CG2 3.96Å; F442-V446 HydrophobicContact CE1-CB 4.42Å; F442-V446 HydrophobicContact CE1-CG2 3.41Å; F442-V446 VanDerWaalsContact CE1-CG2 3.41Å; F442-V446 HydrophobicContact CE2-CG2 4.06Å; F442-V446 HydrophobicContact CZ-CG2 3.45Å; F442-V446 VanDerWaalsContact CZ-CG2 3.45Å; F442-V446 PolarHBondContact O-N 3.21Å; I444-V446 VanDerWaalsContact C-N 3.26Å; I444-V446 PolarHBondContact O-N 3.01Å; V446-S448 PolarHBondContact O-N 3.27Å
447	N	81.7	Confident	88.7	Confident	135 Å²	135	44.8 Å²	44.8	72%	0.722	21%	0.212	S	C	*	.	T	Hydrogen-bonded Turn	trans	52.5	40.4	-177.7	-163.4	36.1	0	0	0	113.2	D443 I444 W445 R449	D443-N447 PolarHBondContact O-N 3.48Å; I444-N447 WeakPolarHBondContact O-CA 3.27Å; I444-N447 PolarHBondContact O-N 2.65Å; W445-N447 VanDerWaalsContact C-N 3.3Å; N447-R449 PolarHBondContact O-N 3.35Å; N447-R449 VanDerWaalsContact O-N 3.12Å
448	S	80.2	Confident	88.9	Confident	9 Å²	9	45.8 Å²	45.8	6%	0.063	22%	0.218	C	C	.	.			trans	-73.9	99.2	-177.8	177.8	0	0	0	0	110.4	D443 V446 K450 N451	D443-S448 WeakPolarHBondContact O-CB 3.23Å; D443-S448 PolarHBondContact O-N 3.15Å; D443-S448 WeakPolarHBondContact OD1-CB 3.47Å; D443-S448 PolarHBondContact OD1-OG 2.89Å; V446-S448 PolarHBondContact O-N 3.27Å; S448-K450 PolarHBondContact O-N 3.31Å; S448-K450 VanDerWaalsContact O-N 3.11Å; S448-N451 PolarHBondContact O-N 2.95Å; S448-N451 PolarHBondContact O-OD1 3.21Å
449	R	72.9	Confident	89	Confident	238 Å²	238	51.1 Å²	51.1	90%	0.898	24%	0.241	S	C	*	.	T	Hydrogen-bonded Turn	trans	-58.6	-25.3	-177.6	-71.6	-146.5	-88.6	-176.4	-7.7	114.8	N447	N447-R449 PolarHBondContact O-N 3.35Å; N447-R449 VanDerWaalsContact O-N 3.12Å
450	K	81.8	Confident	89.1	Confident	169 Å²	169	51.2 Å²	51.2	74%	0.735	24%	0.242	S	C	*	.	T	Hydrogen-bonded Turn	trans	-98.1	0.5	-177.4	-64.9	-173	-177.5	179.6	0	114.1	S448 V452 I455	S448-K450 PolarHBondContact O-N 3.31Å; S448-K450 VanDerWaalsContact O-N 3.11Å; K450-V452 HydrophobicContact CB-CG2 3.81Å; K450-V452 PolarHBondContact O-N 2.88Å; K450-I455 WeakPolarHBondContact O-CD1 3.33Å
451	N	87.8	Confident	89.3	Confident	42 Å²	42	51.2 Å²	51.2	23%	0.225	24%	0.242	C	C	.	.			trans	51.9	44.6	-179	-46.2	-32	0	0	0	112.7	R189 D443 S448 Y453 F454 I455	R189-N451 PolarHBondContact NH1-ND2 3.46Å; R189-N451 PolarHBondContact NH1-OD1 2.93Å; R189-N451 PolarHBondContact NH2-OD1 3.41Å; D443-N451 VanDerWaalsContact CG-CA 3.47Å; D443-N451 WeakPolarHBondContact OD2-CA 3.48Å; S448-N451 PolarHBondContact O-N 2.95Å; S448-N451 PolarHBondContact O-OD1 3.21Å; N451-Y453 VanDerWaalsContact C-N 3.32Å; N451-Y453 PolarHBondContact O-N 2.94Å; N451-F454 HydrophobicContact CB-CB 4.32Å; N451-F454 PolarHBondContact O-N 3.35Å; N451-I455 HydrophobicContact CB-CD1 4.35Å; N451-I455 HydrophobicContact CB-CG1 4.39Å; N451-I455 WeakPolarHBondContact O-CB 3.46Å; N451-I455 WeakPolarHBondContact O-CG1 3.46Å; N451-I455 PolarHBondContact O-N 3.48Å
452	V	90.8	Very high	89.6	Confident	52 Å²	52	53.1 Å²	53.1	32%	0.315	25%	0.253	S	S	.	.	H	α-helix	trans	-63.1	-40.2	-168.6	-177.2	0	0	0	0	111	D443 K450 S456 V496	D443-V452 PolarHBondContact OD1-N 3.39Å; D443-V452 PolarHBondContact OD2-N 2.9Å; K450-V452 HydrophobicContact CB-CG2 3.81Å; K450-V452 PolarHBondContact O-N 2.88Å; V452-S456 WeakPolarHBondContact O-CB 3.49Å; V452-S456 PolarHBondContact O-N 2.93Å; V452-V496 HydrophobicContact CG1-CG1 4.1Å
453	Y	92.3	Very high	89.8	Confident	2 Å²	2	55.7 Å²	55.7	1%	0.008	27%	0.266	C	S	.	.	H	α-helix	trans	-67.7	-47	179.9	-72.2	-88.5	0	0	0	111.4	F442 D443 N451 C457 V496 A497 E502 F506	F442-Y453 HydrophobicContact CD1-CD1 4.32Å; F442-Y453 AromaticContact CD1-CD2 3.88Å; F442-Y453 HydrophobicContact CD1-CD2 3.88Å; F442-Y453 HydrophobicContact CD1-CE1 4.25Å; F442-Y453 AromaticContact CD1-CE2 3.81Å; F442-Y453 HydrophobicContact CD1-CE2 3.81Å; F442-Y453 HydrophobicContact CD1-CG 4.14Å; F442-Y453 HydrophobicContact CE1-CD2 4.26Å; F442-Y453 HydrophobicContact CE1-CE1 4.19Å; F442-Y453 AromaticContact CE1-CE2 3.71Å; F442-Y453 HydrophobicContact CE1-CE2 3.71Å; F442-Y453 AromaticContact CE1-CZ 3.66Å; D443-Y453 WeakPolarHBondContact OD1-CD2 3.44Å; D443-Y453 PolarHBondContact OD1-N 3.45Å; D443-Y453 PolarHBondContact OD2-N 3.33Å; D443-Y453 VanDerWaalsContact OD2-N 3.16Å; N451-Y453 VanDerWaalsContact C-N 3.32Å; N451-Y453 PolarHBondContact O-N 2.94Å; Y453-C457 VanDerWaalsContact O-CB 3.25Å; Y453-C457 WeakPolarHBondContact O-CB 3.24Å; Y453-C457 PolarHBondContact O-N 2.98Å; Y453-V496 HydrophobicContact CD1-CG1 3.92Å; Y453-V496 HydrophobicContact CE1-CB 4.38Å; Y453-V496 HydrophobicContact CE1-CG1 3.76Å; Y453-V496 HydrophobicContact CG-CG1 4.37Å; Y453-A497 HydrophobicContact CE1-CB 4.01Å; Y453-A497 WeakPolarHBondContact OH-CA 3.45Å; Y453-E502 WeakPolarHBondContact CE2-OE2 3.27Å; Y453-E502 PolarHBondContact OH-OE2 3.37Å; Y453-F506 HydrophobicContact CD1-CD2 4.41Å; Y453-F506 AromaticContact CD1-CE2 3.9Å; Y453-F506 HydrophobicContact CD1-CE2 3.9Å; Y453-F506 HydrophobicContact CD1-CZ 4.27Å; Y453-F506 HydrophobicContact CE1-CD2 4.09Å; Y453-F506 HydrophobicContact CE1-CE2 4.01Å; Y453-F506 HydrophobicContact CE1-CZ 4.42Å
454	F	94.5	Very high	89.9	Confident	19 Å²	19	55.7 Å²	55.7	8%	0.083	27%	0.266	C	S	.	.	H	α-helix	trans	-59.9	-53.1	177.8	174.6	-110.5	0	0	0	112	A182 L186 V436 D443 N451 S456 C457 V458	A182-F454 HydrophobicContact CB-CZ 4.41Å; L186-F454 HydrophobicContact CD2-CE1 3.8Å; L186-F454 HydrophobicContact CD2-CZ 3.88Å; L186-F454 HydrophobicContact CG-CE1 4.14Å; L186-F454 HydrophobicContact CG-CZ 3.76Å; V436-F454 HydrophobicContact CG1-CD2 3.79Å; V436-F454 HydrophobicContact CG1-CE2 3.66Å; D443-F454 WeakPolarHBondContact OD2-CB 3.32Å; D443-F454 PolarHBondContact OD2-N 3.38Å; N451-F454 HydrophobicContact CB-CB 4.32Å; N451-F454 PolarHBondContact O-N 3.35Å; F454-S456 PolarHBondContact O-N 3.01Å; F454-C457 PolarHBondContact O-N 3.48Å; F454-V458 HydrophobicContact CD2-CG2 4.06Å; F454-V458 HydrophobicContact CE1-CG2 4.38Å; F454-V458 HydrophobicContact CE2-CG2 3.68Å; F454-V458 HydrophobicContact CZ-CG2 3.86Å; F454-V458 VanDerWaalsContact O-CG2 3.32Å; F454-V458 WeakPolarHBondContact O-CG2 3.47Å; F454-V458 PolarHBondContact O-N 2.97Å
455	I	94.3	Very high	90.1	Very high	98 Å²	98	54.4 Å²	54.4	50%	0.503	26%	0.259	S	S	.	.	H	α-helix	trans	-64.3	-42.7	-176.8	-65.5	173.6	0	0	0	110.8	K450 N451 V458 F459	K450-I455 WeakPolarHBondContact O-CD1 3.33Å; N451-I455 HydrophobicContact CB-CD1 4.35Å; N451-I455 HydrophobicContact CB-CG1 4.39Å; N451-I455 WeakPolarHBondContact O-CB 3.46Å; N451-I455 WeakPolarHBondContact O-CG1 3.46Å; N451-I455 PolarHBondContact O-N 3.48Å; I455-V458 PolarHBondContact O-N 3.34Å; I455-F459 WeakPolarHBondContact O-CB 3.42Å; I455-F459 PolarHBondContact O-N 3.29Å
456	S	94.6	Very high	90.4	Very high	30 Å²	30	52.7 Å²	52.7	21%	0.21	26%	0.256	C	S	.	.	H	α-helix	trans	-63.7	-42.7	179.1	-165.7	0	0	0	0	111.7	V452 F454 F459 A460 T492 V496	V452-S456 WeakPolarHBondContact O-CB 3.49Å; V452-S456 PolarHBondContact O-N 2.93Å; F454-S456 PolarHBondContact O-N 3.01Å; S456-F459 PolarHBondContact O-N 2.79Å; S456-A460 WeakPolarHBondContact O-CB 3.43Å; S456-A460 PolarHBondContact O-N 3.2Å; S456-T492 WeakPolarHBondContact OG-CG2 3.42Å; S456-V496 WeakPolarHBondContact OG-CG2 3.49Å
457	C	95.4	Very high	90.7	Very high	0 Å²	0	53.6 Å²	53.6	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-70.1	-38	179.3	-163.7	0	0	0	0	112.8	V436 C439 Y453 F454 F459 A460 Y461	V436-C457 HydrophobicContact CG2-CB 4.18Å; V436-C457 VanDerWaalsContact CG2-SG 3.54Å; C439-C457 HydrophobicContact CB-CB 4.26Å; Y453-C457 VanDerWaalsContact O-CB 3.25Å; Y453-C457 WeakPolarHBondContact O-CB 3.24Å; Y453-C457 PolarHBondContact O-N 2.98Å; F454-C457 PolarHBondContact O-N 3.48Å; C457-F459 VanDerWaalsContact C-N 3.34Å; C457-A460 PolarHBondContact O-N 3.48Å; C457-Y461 PolarHBondContact O-N 3.41Å
458	V	95.9	Very high	91	Very high	22 Å²	22	47.4 Å²	47.4	13%	0.133	23%	0.226	C	C	.	.	H	α-helix	trans	-63.7	-40.9	173.2	170.7	0	0	0	0	110.9	I178 V436 F454 I455 Y461 L462	I178-V458 HydrophobicContact CG2-CG1 4.46Å; V436-V458 HydrophobicContact CG1-CG2 3.63Å; F454-V458 HydrophobicContact CD2-CG2 4.06Å; F454-V458 HydrophobicContact CE1-CG2 4.38Å; F454-V458 HydrophobicContact CE2-CG2 3.68Å; F454-V458 HydrophobicContact CZ-CG2 3.86Å; F454-V458 VanDerWaalsContact O-CG2 3.32Å; F454-V458 WeakPolarHBondContact O-CG2 3.47Å; F454-V458 PolarHBondContact O-N 2.97Å; I455-V458 PolarHBondContact O-N 3.34Å; V458-Y461 WeakPolarHBondContact O-CB 3.46Å; V458-Y461 PolarHBondContact O-N 3.44Å; V458-L462 PolarHBondContact O-N 3.3Å
459	F	94.8	Very high	91.2	Very high	112 Å²	112	48 Å²	48	49%	0.491	23%	0.228	S	C	.	.	H	α-helix	trans	-66.3	-40.5	176	-175.2	-105.4	0	0	0	112	I455 S456 C457 Y461 L462 L463	I455-F459 WeakPolarHBondContact O-CB 3.42Å; I455-F459 PolarHBondContact O-N 3.29Å; S456-F459 PolarHBondContact O-N 2.79Å; C457-F459 VanDerWaalsContact C-N 3.34Å; F459-Y461 VanDerWaalsContact C-N 3.33Å; F459-Y461 PolarHBondContact O-N 2.75Å; F459-L462 HydrophobicContact CD2-CD2 4.33Å; F459-L462 PolarHBondContact O-N 3.36Å; F459-L463 HydrophobicContact CD1-CD1 3.88Å; F459-L463 HydrophobicContact CD1-CG 4.29Å; F459-L463 HydrophobicContact CE1-CD1 3.37Å; F459-L463 HydrophobicContact CE1-CD2 4.43Å; F459-L463 HydrophobicContact CE1-CG 3.9Å; F459-L463 HydrophobicContact CZ-CD1 3.92Å; F459-L463 HydrophobicContact CZ-CD2 4.14Å; F459-L463 HydrophobicContact CZ-CG 4.04Å; F459-L463 WeakPolarHBondContact O-CG 3.45Å; F459-L463 PolarHBondContact O-N 2.94Å
460	A	96	Very high	91.8	Very high	1 Å²	1	38.1 Å²	38.1	1%	0.008	20%	0.197	C	C	.	.	H	α-helix	trans	-62.2	-39.8	173.9	0	0	0	0	0	112.3	S456 C457 L463 G464 T489 T492	S456-A460 WeakPolarHBondContact O-CB 3.43Å; S456-A460 PolarHBondContact O-N 3.2Å; C457-A460 PolarHBondContact O-N 3.48Å; A460-L463 PolarHBondContact O-N 2.9Å; A460-G464 PolarHBondContact O-N 3.44Å; A460-T489 HydrophobicContact CB-CG2 4.33Å; A460-T492 HydrophobicContact CB-CG2 3.99Å
461	Y	96	Very high	92	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-60.7	-47.7	173.4	177.8	-97.3	0	0	0	111.8	A177 I178 V181 D428 P432 C457 V458 F459 L463 G464 L465 L485	A177-Y461 HydrophobicContact CB-CE1 4.35Å; I178-Y461 HydrophobicContact CG1-CD1 4.41Å; I178-Y461 HydrophobicContact CG1-CE1 4.41Å; V181-Y461 HydrophobicContact CB-CD1 4.41Å; V181-Y461 HydrophobicContact CB-CE1 4.31Å; V181-Y461 HydrophobicContact CG1-CD1 4.43Å; V181-Y461 HydrophobicContact CG2-CD1 4.22Å; V181-Y461 HydrophobicContact CG2-CE1 3.74Å; V181-Y461 HydrophobicContact CG2-CE2 4.18Å; D428-Y461 WeakPolarHBondContact O-CE2 3.4Å; D428-Y461 PolarHBondContact O-OH 3.48Å; P432-Y461 HydrophobicContact CB-CD2 3.64Å; P432-Y461 HydrophobicContact CB-CE2 3.85Å; P432-Y461 HydrophobicContact CG-CD2 4.22Å; P432-Y461 HydrophobicContact CG-CE2 4.03Å; C457-Y461 PolarHBondContact O-N 3.41Å; V458-Y461 WeakPolarHBondContact O-CB 3.46Å; V458-Y461 PolarHBondContact O-N 3.44Å; F459-Y461 VanDerWaalsContact C-N 3.33Å; F459-Y461 PolarHBondContact O-N 2.75Å; Y461-L463 PolarHBondContact O-N 2.92Å; Y461-G464 PolarHBondContact O-N 3.04Å; Y461-L465 HydrophobicContact CE1-CD2 3.97Å; Y461-L465 WeakPolarHBondContact O-CB 3.42Å; Y461-L465 PolarHBondContact O-N 2.82Å; Y461-L485 HydrophobicContact CD2-CD2 3.73Å; Y461-L485 HydrophobicContact CE2-CD1 4.22Å; Y461-L485 HydrophobicContact CE2-CD2 3.73Å; Y461-L485 HydrophobicContact CG-CD2 4.47Å
462	L	94.8	Very high	91.6	Very high	50 Å²	50	32.5 Å²	32.5	26%	0.262	18%	0.175	S	C	.	.	H	α-helix	trans	-56.9	-48.7	174.9	161.1	63.5	0	0	0	111.4	L174 I178 V458 F459 G464 L465 V466	L174-L462 HydrophobicContact CD1-CD1 4.08Å; L174-L462 HydrophobicContact CD2-CD1 4.16Å; L174-L462 HydrophobicContact CG-CD1 4.35Å; I178-L462 HydrophobicContact CD1-CB 4.04Å; I178-L462 HydrophobicContact CD1-CD1 3.34Å; I178-L462 HydrophobicContact CD1-CG 4.12Å; I178-L462 HydrophobicContact CG1-CB 4.37Å; I178-L462 HydrophobicContact CG1-CD1 4.44Å; V458-L462 PolarHBondContact O-N 3.3Å; F459-L462 HydrophobicContact CD2-CD2 4.33Å; F459-L462 PolarHBondContact O-N 3.36Å; L462-G464 PolarHBondContact O-N 3.41Å; L462-L465 PolarHBondContact O-N 3.48Å; L462-V466 HydrophobicContact CD1-CG2 3.69Å; L462-V466 WeakPolarHBondContact O-CB 3.49Å; L462-V466 VanDerWaalsContact O-CG2 3.29Å; L462-V466 WeakPolarHBondContact O-CG2 3.35Å; L462-V466 PolarHBondContact O-N 3.39Å
463	L	94.4	Very high	90.9	Very high	56 Å²	56	32.5 Å²	32.5	29%	0.293	17%	0.173	S	C	.	.	H	α-helix	trans	-62.2	-43	178.9	-73.5	-178.8	0	0	0	112.2	F459 A460 Y461 V466 L467 F488	F459-L463 HydrophobicContact CD1-CD1 3.88Å; F459-L463 HydrophobicContact CD1-CG 4.29Å; F459-L463 HydrophobicContact CE1-CD1 3.37Å; F459-L463 HydrophobicContact CE1-CD2 4.43Å; F459-L463 HydrophobicContact CE1-CG 3.9Å; F459-L463 HydrophobicContact CZ-CD1 3.92Å; F459-L463 HydrophobicContact CZ-CD2 4.14Å; F459-L463 HydrophobicContact CZ-CG 4.04Å; F459-L463 WeakPolarHBondContact O-CG 3.45Å; F459-L463 PolarHBondContact O-N 2.94Å; A460-L463 PolarHBondContact O-N 2.9Å; Y461-L463 PolarHBondContact O-N 2.92Å; L463-V466 PolarHBondContact O-N 2.91Å; L463-L467 WeakPolarHBondContact O-CB 3.24Å; L463-L467 PolarHBondContact O-N 3.13Å; L463-F488 HydrophobicContact CB-CD1 3.98Å; L463-F488 HydrophobicContact CB-CE1 4.07Å
464	G	93.3	Very high	90.2	Very high	0 Å²	0	37.2 Å²	37.2	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-59.5	-47	175.7	0	0	0	0	0	111.6	A460 Y461 L462 L467 T468	A460-G464 PolarHBondContact O-N 3.44Å; Y461-G464 PolarHBondContact O-N 3.04Å; L462-G464 PolarHBondContact O-N 3.41Å; G464-L467 WeakPolarHBondContact O-CB 3.43Å; G464-L467 PolarHBondContact O-N 3.15Å; G464-T468 WeakPolarHBondContact O-CG2 3.44Å; G464-T468 PolarHBondContact O-N 2.98Å
465	L	91.2	Very high	89.2	Confident	0 Å²	0	39.2 Å²	39.2	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-69.4	-33.8	-179.4	-167.1	59.1	0	0	0	112.8	L174 A177 L424 Y461 L462 L467 T468 F469 L485	L174-L465 HydrophobicContact CD1-CB 4.02Å; L174-L465 HydrophobicContact CD1-CD2 3.54Å; L174-L465 HydrophobicContact CD1-CG 3.73Å; A177-L465 HydrophobicContact CB-CD2 3.6Å; L424-L465 HydrophobicContact CD1-CD1 4.08Å; Y461-L465 HydrophobicContact CE1-CD2 3.97Å; Y461-L465 WeakPolarHBondContact O-CB 3.42Å; Y461-L465 PolarHBondContact O-N 2.82Å; L462-L465 PolarHBondContact O-N 3.48Å; L465-L467 VanDerWaalsContact C-N 3.34Å; L465-T468 WeakPolarHBondContact CA-OG1 3Å; L465-T468 PolarHBondContact O-OG1 3.39Å; L465-F469 HydrophobicContact CD1-CD2 4.37Å; L465-F469 HydrophobicContact CD1-CE2 3.8Å; L465-F469 HydrophobicContact CD1-CZ 4.38Å; L465-F469 HydrophobicContact CD2-CE2 4.42Å; L465-F469 HydrophobicContact CG-CD2 4.19Å; L465-F469 HydrophobicContact CG-CE2 3.78Å; L465-F469 WeakPolarHBondContact O-CD2 3.31Å; L465-F469 PolarHBondContact O-N 3.4Å; L465-L485 HydrophobicContact CB-CD2 3.94Å
466	V	91.3	Very high	87.8	Confident	31 Å²	31	37.8 Å²	37.8	19%	0.188	22%	0.224	C	C	.	.	H	α-helix	trans	-67.1	-40.5	172.4	171.3	0	0	0	0	110.4	L11 L174 L462 L463 F469 A470	L11-V466 HydrophobicContact CD2-CG1 3.56Å; L174-V466 HydrophobicContact CD1-CG2 4.17Å; L174-V466 HydrophobicContact CD2-CG2 3.84Å; L462-V466 HydrophobicContact CD1-CG2 3.69Å; L462-V466 WeakPolarHBondContact O-CB 3.49Å; L462-V466 VanDerWaalsContact O-CG2 3.29Å; L462-V466 WeakPolarHBondContact O-CG2 3.35Å; L462-V466 PolarHBondContact O-N 3.39Å; L463-V466 PolarHBondContact O-N 2.91Å; V466-F469 PolarHBondContact O-N 3.42Å; V466-A470 WeakPolarHBondContact O-CB 3.17Å; V466-A470 PolarHBondContact O-N 3.49Å
467	L	90.6	Very high	86.4	Confident	60 Å²	60	43 Å²	43	31%	0.314	25%	0.246	S	C	.	.	H	α-helix	trans	-65.1	-41.4	176.2	-175.5	62.6	0	0	0	111.9	L463 G464 L465 F469 A470 V471 Y484 F488	L463-L467 WeakPolarHBondContact O-CB 3.24Å; L463-L467 PolarHBondContact O-N 3.13Å; G464-L467 WeakPolarHBondContact O-CB 3.43Å; G464-L467 PolarHBondContact O-N 3.15Å; L465-L467 VanDerWaalsContact C-N 3.34Å; L467-F469 VanDerWaalsContact C-N 3.33Å; L467-F469 PolarHBondContact O-N 2.9Å; L467-A470 PolarHBondContact O-N 2.94Å; L467-V471 HydrophobicContact CD1-CG2 3.97Å; L467-V471 HydrophobicContact CG-CG2 4.29Å; L467-V471 WeakPolarHBondContact O-CG2 3.25Å; L467-V471 PolarHBondContact O-N 2.87Å; L467-Y484 HydrophobicContact CD2-CD1 3.59Å; L467-Y484 HydrophobicContact CD2-CE1 4.22Å; L467-Y484 HydrophobicContact CD2-CG 4.43Å; L467-Y484 HydrophobicContact CG-CD1 3.86Å; L467-Y484 HydrophobicContact CG-CE1 4.31Å; L467-Y484 HydrophobicContact CG-CG 4.49Å; L467-F488 HydrophobicContact CD2-CE2 3.43Å; L467-F488 VanDerWaalsContact CD2-CE2 3.43Å; L467-F488 HydrophobicContact CD2-CZ 3.66Å
468	T	88.5	Confident	85	Confident	4 Å²	4	46 Å²	46	3%	0.025	28%	0.277	C	S	.	.	H	α-helix	trans	-56.4	-49.2	175.7	55.8	0	0	0	0	110.8	G464 L465 V471 M472 A481 Y484 L485	G464-T468 WeakPolarHBondContact O-CG2 3.44Å; G464-T468 PolarHBondContact O-N 2.98Å; L465-T468 WeakPolarHBondContact CA-OG1 3Å; L465-T468 PolarHBondContact O-OG1 3.39Å; T468-V471 PolarHBondContact O-N 3.24Å; T468-M472 WeakPolarHBondContact O-CB 3.14Å; T468-M472 VanDerWaalsContact O-CG 3.25Å; T468-M472 WeakPolarHBondContact O-CG 3.37Å; T468-M472 PolarHBondContact O-N 2.74Å; T468-A481 HydrophobicContact CG2-CB 4.08Å; T468-A481 WeakPolarHBondContact CG2-O 3.36Å; T468-Y484 HydrophobicContact CG2-CD2 3.7Å; T468-Y484 HydrophobicContact CG2-CG 4Å; T468-L485 HydrophobicContact CG2-CG 4.47Å
469	F	84.6	Confident	84.1	Confident	21 Å²	21	46.9 Å²	46.9	9%	0.092	28%	0.28	C	S	.	.	H	α-helix	trans	-66.4	-40.6	179.6	-73.5	-57.9	0	0	0	111.9	I170 L173 L465 V466 L467 V471 M472 L473	I170-F469 HydrophobicContact CG2-CB 4.16Å; I170-F469 HydrophobicContact CG2-CD1 3.96Å; I170-F469 HydrophobicContact CG2-CD2 3.94Å; I170-F469 HydrophobicContact CG2-CE1 4.35Å; I170-F469 HydrophobicContact CG2-CE2 4.33Å; I170-F469 HydrophobicContact CG2-CG 3.76Å; L173-F469 HydrophobicContact CD2-CE1 4.28Å; L173-F469 HydrophobicContact CD2-CZ 3.81Å; L173-F469 HydrophobicContact CG-CZ 4.34Å; L465-F469 HydrophobicContact CD1-CD2 4.37Å; L465-F469 HydrophobicContact CD1-CE2 3.8Å; L465-F469 HydrophobicContact CD1-CZ 4.38Å; L465-F469 HydrophobicContact CD2-CE2 4.42Å; L465-F469 HydrophobicContact CG-CD2 4.19Å; L465-F469 HydrophobicContact CG-CE2 3.78Å; L465-F469 WeakPolarHBondContact O-CD2 3.31Å; L465-F469 PolarHBondContact O-N 3.4Å; V466-F469 PolarHBondContact O-N 3.42Å; L467-F469 VanDerWaalsContact C-N 3.33Å; L467-F469 PolarHBondContact O-N 2.9Å; F469-V471 PolarHBondContact O-N 3.33Å; F469-M472 PolarHBondContact O-N 3.14Å; F469-L473 WeakPolarHBondContact O-CB 3.34Å; F469-L473 VanDerWaalsContact O-CG 3.26Å; F469-L473 WeakPolarHBondContact O-CG 3.36Å; F469-L473 PolarHBondContact O-N 2.92Å
470	A	85.3	Confident	83.6	Confident	31 Å²	31	41.7 Å²	41.7	26%	0.256	26%	0.257	S	S	.	.	H	α-helix	trans	-60.1	-45.5	177.4	0	0	0	0	0	111.9	V466 L467 L473 L474	V466-A470 WeakPolarHBondContact O-CB 3.17Å; V466-A470 PolarHBondContact O-N 3.49Å; L467-A470 PolarHBondContact O-N 2.94Å; A470-L473 PolarHBondContact O-N 2.92Å; A470-L474 WeakPolarHBondContact O-CB 3.22Å; A470-L474 VanDerWaalsContact O-CG 3.31Å; A470-L474 WeakPolarHBondContact O-CG 3.43Å; A470-L474 PolarHBondContact O-N 3.09Å
471	V	85.4	Confident	83.1	Confident	27 Å²	27	42.2 Å²	42.2	16%	0.164	26%	0.262	C	S	.	.	H	α-helix	trans	-70.3	-39.4	178.7	-171.8	0	0	0	0	111.1	L467 T468 F469 L473 L474 S475 Q479 Y484	L467-V471 HydrophobicContact CD1-CG2 3.97Å; L467-V471 HydrophobicContact CG-CG2 4.29Å; L467-V471 WeakPolarHBondContact O-CG2 3.25Å; L467-V471 PolarHBondContact O-N 2.87Å; T468-V471 PolarHBondContact O-N 3.24Å; F469-V471 PolarHBondContact O-N 3.33Å; V471-L473 VanDerWaalsContact C-N 3.29Å; V471-L473 PolarHBondContact O-N 3.24Å; V471-L474 PolarHBondContact O-N 3.49Å; V471-L474 VanDerWaalsContact O-N 3.17Å; V471-S475 WeakPolarHBondContact O-CB 3.14Å; V471-S475 PolarHBondContact O-N 3.43Å; V471-S475 PolarHBondContact O-OG 3.31Å; V471-Q479 VanDerWaalsContact CG1-CD 3.47Å; V471-Q479 VanDerWaalsContact CG1-NE2 3.31Å; V471-Y484 HydrophobicContact CG2-CE1 4.17Å
472	M	79.4	Confident	82.8	Confident	66 Å²	66	42.7 Å²	42.7	33%	0.325	26%	0.264	S	S	.	.	H	α-helix	trans	-57.6	-41.2	173.6	-75.3	176.9	67	0	0	112.3	T468 F469 G476 Q479	T468-M472 WeakPolarHBondContact O-CB 3.14Å; T468-M472 VanDerWaalsContact O-CG 3.25Å; T468-M472 WeakPolarHBondContact O-CG 3.37Å; T468-M472 PolarHBondContact O-N 2.74Å; F469-M472 PolarHBondContact O-N 3.14Å; M472-G476 PolarHBondContact O-N 3.44Å; M472-Q479 HydrophobicContact CG-CB 4.18Å
473	L	76.8	Confident	82.7	Confident	52 Å²	52	43 Å²	43	27%	0.272	27%	0.265	S	S	.	.	H	α-helix	trans	-70	-32.9	177.5	-70	174.8	0	0	0	113.2	K165 I166 I170 F469 A470 V471	K165-L473 WeakPolarHBondContact O-CD2 3.48Å; I166-L473 HydrophobicContact CG1-CD1 4.36Å; I170-L473 HydrophobicContact CD1-CD1 4.24Å; I170-L473 HydrophobicContact CD1-CD2 4.18Å; F469-L473 WeakPolarHBondContact O-CB 3.34Å; F469-L473 VanDerWaalsContact O-CG 3.26Å; F469-L473 WeakPolarHBondContact O-CG 3.36Å; F469-L473 PolarHBondContact O-N 2.92Å; A470-L473 PolarHBondContact O-N 2.92Å; V471-L473 VanDerWaalsContact C-N 3.29Å; V471-L473 PolarHBondContact O-N 3.24Å
474	L	77.9	Confident	82.6	Confident	102 Å²	102	42.4 Å²	42.4	53%	0.534	26%	0.26	S	S	.	.	H	α-helix	trans	-77.3	-44.9	178.2	-76.6	170.6	0	0	0	112.5	I18 A470 V471	I18-L474 HydrophobicContact CD1-CD2 3.35Å; I18-L474 HydrophobicContact CD1-CG 3.96Å; I18-L474 HydrophobicContact CG1-CD2 3.8Å; I18-L474 HydrophobicContact CG2-CD2 4.22Å; A470-L474 WeakPolarHBondContact O-CB 3.22Å; A470-L474 VanDerWaalsContact O-CG 3.31Å; A470-L474 WeakPolarHBondContact O-CG 3.43Å; A470-L474 PolarHBondContact O-N 3.09Å; V471-L474 PolarHBondContact O-N 3.49Å; V471-L474 VanDerWaalsContact O-N 3.17Å
475	S	72.1	Confident	82.6	Confident	60 Å²	60	42.4 Å²	42.4	42%	0.42	26%	0.26	S	S	.	.	H	α-helix	trans	-82.1	-20.1	-175.9	-60.7	0	0	0	0	113.2	V471 M477	V471-S475 WeakPolarHBondContact O-CB 3.14Å; V471-S475 PolarHBondContact O-N 3.43Å; V471-S475 PolarHBondContact O-OG 3.31Å; S475-M477 PolarHBondContact O-N 3.04Å; S475-M477 VanDerWaalsContact O-N 3.11Å
476	G	64.8	Low	82.8	Confident	69 Å²	69	42.6 Å²	42.6	71%	0.711	26%	0.261	S	S	*	.			trans	64.2	12.7	-177.2	0	0	0	0	0	113.9	M472	M472-G476 PolarHBondContact O-N 3.44Å
477	M	65.8	Low	82.9	Confident	139 Å²	139	43.2 Å²	43.2	69%	0.685	27%	0.265	S	S	*	.	S	Bend	trans	-125	141.3	-179	-65.5	176.2	68.8	0	0	109	S475 Q479	S475-M477 PolarHBondContact O-N 3.04Å; S475-M477 VanDerWaalsContact O-N 3.11Å; M477-Q479 PolarHBondContact O-N 3.25Å
478	G	67.2	Low	83.2	Confident	62 Å²	62	43.7 Å²	43.7	64%	0.639	27%	0.265	S	S	*	.			trans	-62.6	128.2	172.2	0	0	0	0	0	110.6
479	Q	77.1	Confident	83.5	Confident	42 Å²	42	43.5 Å²	43.5	20%	0.196	26%	0.264	C	S	.	.			trans	-117.3	150.6	-179.3	-74.2	-170.1	-15.9	0	0	111.6	V471 M472 M477 A481 Y484	V471-Q479 VanDerWaalsContact CG1-CD 3.47Å; V471-Q479 VanDerWaalsContact CG1-NE2 3.31Å; M472-Q479 HydrophobicContact CG-CB 4.18Å; M477-Q479 PolarHBondContact O-N 3.25Å; Q479-A481 PolarHBondContact O-N 3.22Å; Q479-Y484 PolarHBondContact OE1-OH 3.31Å
480	P	83.4	Confident	84	Confident	3 Å²	3	43.4 Å²	43.4	2%	0.019	26%	0.264	C	S	.	.			trans	-64.8	117.7	175.7	18.1	-19.2	0	0	0	110.1	D350 V354 F355 L482 L483	D350-P480 HydrophobicContact CB-CB 4.19Å; D350-P480 VanDerWaalsContact OD2-CA 3.31Å; D350-P480 WeakPolarHBondContact OD2-CA 3.45Å; D350-P480 WeakPolarHBondContact OD2-CB 3.32Å; V354-P480 HydrophobicContact CB-CB 4.47Å; V354-P480 HydrophobicContact CB-CG 4.29Å; V354-P480 HydrophobicContact CG1-CG 4.32Å; V354-P480 HydrophobicContact CG2-CB 4.08Å; V354-P480 HydrophobicContact CG2-CG 4.41Å; F355-P480 HydrophobicContact CD2-CG 4.32Å; F355-P480 HydrophobicContact CE2-CG 3.46Å; F355-P480 VanDerWaalsContact CE2-CG 3.46Å; F355-P480 HydrophobicContact CZ-CG 3.88Å; P480-L482 VanDerWaalsContact C-N 3.33Å; P480-L482 PolarHBondContact O-N 3.02Å; P480-L483 HydrophobicContact CB-CB 4.33Å; P480-L483 HydrophobicContact CG-CB 4.09Å; P480-L483 HydrophobicContact CG-CD2 4.2Å; P480-L483 WeakPolarHBondContact O-CB 3.44Å; P480-L483 PolarHBondContact O-N 2.89Å
481	A	86.1	Confident	84.5	Confident	12 Å²	12	46.9 Å²	46.9	10%	0.099	28%	0.277	C	S	.	.	T	Hydrogen-bonded Turn	trans	-69.1	-33.4	-174.7	0	0	0	0	0	112	D428 T468 Q479 L483 Y484 L485	D428-A481 HydrophobicContact CB-CB 4.23Å; T468-A481 HydrophobicContact CG2-CB 4.08Å; T468-A481 WeakPolarHBondContact CG2-O 3.36Å; Q479-A481 PolarHBondContact O-N 3.22Å; A481-L483 PolarHBondContact O-N 2.69Å; A481-Y484 PolarHBondContact O-N 2.96Å; A481-L485 HydrophobicContact CB-CD1 4.18Å; A481-L485 WeakPolarHBondContact O-CG 3.25Å; A481-L485 PolarHBondContact O-N 2.82Å; A481-L485 VanDerWaalsContact O-N 3.12Å
482	L	89.8	Confident	85	Confident	9 Å²	9	47.5 Å²	47.5	5%	0.047	28%	0.282	C	S	.	.	H	α-helix	trans	-63.1	-24.1	177.8	-65.9	-179.4	0	0	0	112.4	L346 D350 V431 P432 P480 Y484 L485 V486	L346-L482 HydrophobicContact CB-CD1 4.19Å; D350-L482 HydrophobicContact CB-CB 4.3Å; D350-L482 HydrophobicContact CB-CD1 4.29Å; D350-L482 WeakPolarHBondContact OD2-CB 3.39Å; D350-L482 PolarHBondContact OD2-N 2.7Å; V431-L482 HydrophobicContact CB-CD2 4.31Å; V431-L482 HydrophobicContact CG1-CD2 4.3Å; P432-L482 HydrophobicContact CG-CD2 4.16Å; P480-L482 VanDerWaalsContact C-N 3.33Å; P480-L482 PolarHBondContact O-N 3.02Å; L482-Y484 PolarHBondContact O-N 3.32Å; L482-Y484 VanDerWaalsContact O-N 3.16Å; L482-L485 PolarHBondContact O-N 3.09Å; L482-V486 HydrophobicContact CB-CG2 4.11Å; L482-V486 HydrophobicContact CD2-CG2 4.26Å; L482-V486 VanDerWaalsContact O-CB 3.29Å; L482-V486 WeakPolarHBondContact O-CB 3.44Å; L482-V486 WeakPolarHBondContact O-CG2 3.49Å; L482-V486 PolarHBondContact O-N 3.09Å
483	L	91.8	Very high	85.7	Confident	56 Å²	56	44.5 Å²	44.5	29%	0.293	27%	0.267	S	S	.	.	H	α-helix	trans	-53.5	-35.2	175.4	-175	61.2	0	0	0	112.9	L347 V351 F355 P480 A481 P487	L347-L483 VanDerWaalsContact CD1-CA 3.46Å; L347-L483 HydrophobicContact CD1-CB 4.34Å; L347-L483 HydrophobicContact CD1-CD1 3.99Å; V351-L483 HydrophobicContact CG2-CD1 3.99Å; F355-L483 HydrophobicContact CE2-CD2 4.47Å; P480-L483 HydrophobicContact CB-CB 4.33Å; P480-L483 HydrophobicContact CG-CB 4.09Å; P480-L483 HydrophobicContact CG-CD2 4.2Å; P480-L483 WeakPolarHBondContact O-CB 3.44Å; P480-L483 PolarHBondContact O-N 2.89Å; A481-L483 PolarHBondContact O-N 2.69Å; L483-P487 WeakPolarHBondContact O-CD 3.33Å; L483-P487 WeakPolarHBondContact O-CG 3.13Å
484	Y	92.9	Very high	86.5	Confident	45 Å²	45	43.4 Å²	43.4	18%	0.176	27%	0.265	C	S	.	.	H	α-helix	trans	-103.3	-38.2	-179.1	-57	-84.7	0	0	0	111.5	L467 T468 V471 Q479 A481 L482 V486 P487 F488	L467-Y484 HydrophobicContact CD2-CD1 3.59Å; L467-Y484 HydrophobicContact CD2-CE1 4.22Å; L467-Y484 HydrophobicContact CD2-CG 4.43Å; L467-Y484 HydrophobicContact CG-CD1 3.86Å; L467-Y484 HydrophobicContact CG-CE1 4.31Å; L467-Y484 HydrophobicContact CG-CG 4.49Å; T468-Y484 HydrophobicContact CG2-CD2 3.7Å; T468-Y484 HydrophobicContact CG2-CG 4Å; V471-Y484 HydrophobicContact CG2-CE1 4.17Å; Q479-Y484 PolarHBondContact OE1-OH 3.31Å; A481-Y484 PolarHBondContact O-N 2.96Å; L482-Y484 PolarHBondContact O-N 3.32Å; L482-Y484 VanDerWaalsContact O-N 3.16Å; Y484-V486 PolarHBondContact O-N 2.96Å; Y484-P487 WeakPolarHBondContact O-CD 3.34Å; Y484-P487 WeakPolarHBondContact O-CG 3.38Å; Y484-F488 WeakPolarHBondContact O-CD2 3.4Å; Y484-F488 PolarHBondContact O-N 3.45Å
485	L	93.3	Very high	87.3	Confident	0 Å²	0	42.4 Å²	42.4	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-65.1	-42.8	-177.6	-69	168.4	0	0	0	113.2	D428 P432 Y461 L465 T468 A481 L482 T489	D428-L485 HydrophobicContact CB-CD1 4.06Å; P432-L485 HydrophobicContact CG-CB 3.9Å; P432-L485 HydrophobicContact CG-CD1 4.22Å; Y461-L485 HydrophobicContact CD2-CD2 3.73Å; Y461-L485 HydrophobicContact CE2-CD1 4.22Å; Y461-L485 HydrophobicContact CE2-CD2 3.73Å; Y461-L485 HydrophobicContact CG-CD2 4.47Å; L465-L485 HydrophobicContact CB-CD2 3.94Å; T468-L485 HydrophobicContact CG2-CG 4.47Å; A481-L485 HydrophobicContact CB-CD1 4.18Å; A481-L485 WeakPolarHBondContact O-CG 3.25Å; A481-L485 PolarHBondContact O-N 2.82Å; A481-L485 VanDerWaalsContact O-N 3.12Å; L482-L485 PolarHBondContact O-N 3.09Å; L485-T489 WeakPolarHBondContact O-CB 3.39Å; L485-T489 WeakPolarHBondContact O-CG2 3.48Å; L485-T489 PolarHBondContact O-N 3.01Å; L485-T489 PolarHBondContact O-OG1 3.46Å
486	V	94.7	Very high	88.3	Confident	3 Å²	3	40.7 Å²	40.7	2%	0.018	25%	0.25	C	S	.	.	H	α-helix	trans	-63.5	-54.6	-177.4	170.8	0	0	0	0	112.5	L343 L347 L482 Y484 F488 T489 L490	L343-V486 HydrophobicContact CB-CG1 3.87Å; L343-V486 HydrophobicContact CB-CG2 4.21Å; L343-V486 HydrophobicContact CD2-CG1 4.43Å; L343-V486 HydrophobicContact CD2-CG2 4.35Å; L343-V486 HydrophobicContact CG-CG2 4.42Å; L347-V486 HydrophobicContact CB-CB 4.45Å; L347-V486 HydrophobicContact CB-CG1 4.32Å; L347-V486 HydrophobicContact CB-CG2 4.35Å; L347-V486 HydrophobicContact CD2-CG1 4.22Å; L482-V486 HydrophobicContact CB-CG2 4.11Å; L482-V486 HydrophobicContact CD2-CG2 4.26Å; L482-V486 VanDerWaalsContact O-CB 3.29Å; L482-V486 WeakPolarHBondContact O-CB 3.44Å; L482-V486 WeakPolarHBondContact O-CG2 3.49Å; L482-V486 PolarHBondContact O-N 3.09Å; Y484-V486 PolarHBondContact O-N 2.96Å; V486-F488 PolarHBondContact O-N 3.39Å; V486-T489 PolarHBondContact O-N 2.82Å; V486-T489 PolarHBondContact O-OG1 3.45Å; V486-L490 HydrophobicContact CG1-CD1 3.61Å; V486-L490 HydrophobicContact CG1-CG 4.3Å; V486-L490 WeakPolarHBondContact O-CB 3.11Å; V486-L490 WeakPolarHBondContact O-CG 3.4Å; V486-L490 PolarHBondContact O-N 2.99Å
487	P	94.3	Very high	89.6	Confident	44 Å²	44	37.4 Å²	37.4	29%	0.286	22%	0.216	S	C	.	.	H	α-helix	trans	-62.9	-41.8	-179.1	22.6	-32.7	0	0	0	112	L483 Y484 T489 I491	L483-P487 WeakPolarHBondContact O-CD 3.33Å; L483-P487 WeakPolarHBondContact O-CG 3.13Å; Y484-P487 WeakPolarHBondContact O-CD 3.34Å; Y484-P487 WeakPolarHBondContact O-CG 3.38Å; P487-T489 PolarHBondContact O-N 3.31Å; P487-I491 HydrophobicContact CB-CD1 4.08Å; P487-I491 WeakPolarHBondContact O-CB 3.38Å; P487-I491 WeakPolarHBondContact O-CD1 3.39Å; P487-I491 WeakPolarHBondContact O-CG1 3.22Å; P487-I491 PolarHBondContact O-N 3.5Å
488	F	95.1	Very high	90.8	Very high	71 Å²	71	32.8 Å²	32.8	31%	0.311	21%	0.205	S	C	.	.	H	α-helix	trans	-59.5	-50.9	178.4	-87.8	-99.7	0	0	0	111.5	L463 L467 Y484 V486 T492	L463-F488 HydrophobicContact CB-CD1 3.98Å; L463-F488 HydrophobicContact CB-CE1 4.07Å; L467-F488 HydrophobicContact CD2-CE2 3.43Å; L467-F488 VanDerWaalsContact CD2-CE2 3.43Å; L467-F488 HydrophobicContact CD2-CZ 3.66Å; Y484-F488 WeakPolarHBondContact O-CD2 3.4Å; Y484-F488 PolarHBondContact O-N 3.45Å; V486-F488 PolarHBondContact O-N 3.39Å; F488-T492 VanDerWaalsContact O-CB 3.22Å; F488-T492 WeakPolarHBondContact O-CB 3.09Å; F488-T492 PolarHBondContact O-N 3.4Å; F488-T492 VanDerWaalsContact O-N 3.09Å; F488-T492 PolarHBondContact O-OG1 3.16Å
489	T	95.6	Very high	92	Very high	0 Å²	0	35 Å²	35	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-70.3	-40.7	-176.4	55.6	0	0	0	0	113.2	P432 A460 L485 V486 P487 S493	P432-T489 HydrophobicContact CB-CG2 4.36Å; A460-T489 HydrophobicContact CB-CG2 4.33Å; L485-T489 WeakPolarHBondContact O-CB 3.39Å; L485-T489 WeakPolarHBondContact O-CG2 3.48Å; L485-T489 PolarHBondContact O-N 3.01Å; L485-T489 PolarHBondContact O-OG1 3.46Å; V486-T489 PolarHBondContact O-N 2.82Å; V486-T489 PolarHBondContact O-OG1 3.45Å; P487-T489 PolarHBondContact O-N 3.31Å; T489-S493 VanDerWaalsContact O-CB 3.31Å; T489-S493 WeakPolarHBondContact O-CB 3.14Å; T489-S493 PolarHBondContact O-N 3.04Å; T489-S493 VanDerWaalsContact O-N 3.14Å; T489-S493 PolarHBondContact O-OG 2.96Å
490	L	95.6	Very high	92.6	Very high	18 Å²	18	37.5 Å²	37.5	9%	0.094	22%	0.217	C	C	.	.	H	α-helix	trans	-69.1	-49.6	178	-75.6	178.6	0	0	0	112.5	F336 V340 L343 L435 V486 S493 A494	F336-L490 HydrophobicContact CE2-CD2 3.92Å; F336-L490 HydrophobicContact CZ-CD2 4.03Å; V340-L490 HydrophobicContact CG2-CD2 4.15Å; L343-L490 HydrophobicContact CB-CD1 4Å; L343-L490 HydrophobicContact CB-CG 4.44Å; L343-L490 HydrophobicContact CD2-CD1 4.41Å; L343-L490 HydrophobicContact CD2-CD2 4.12Å; L343-L490 HydrophobicContact CD2-CG 3.98Å; L435-L490 HydrophobicContact CD2-CD2 3.77Å; L435-L490 HydrophobicContact CD2-CG 4.27Å; V486-L490 HydrophobicContact CG1-CD1 3.61Å; V486-L490 HydrophobicContact CG1-CG 4.3Å; V486-L490 WeakPolarHBondContact O-CB 3.11Å; V486-L490 WeakPolarHBondContact O-CG 3.4Å; V486-L490 PolarHBondContact O-N 2.99Å; L490-S493 PolarHBondContact O-N 2.96Å; L490-A494 WeakPolarHBondContact O-CB 3.5Å; L490-A494 PolarHBondContact O-N 3.4Å
491	I	95.3	Very high	92.7	Very high	104 Å²	104	40.6 Å²	40.6	53%	0.533	25%	0.249	S	C	.	.	H	α-helix	trans	-63.9	-46.6	-177.5	-65.6	169.1	0	0	0	109.3	P487 S493 A494 V495	P487-I491 HydrophobicContact CB-CD1 4.08Å; P487-I491 WeakPolarHBondContact O-CB 3.38Å; P487-I491 WeakPolarHBondContact O-CD1 3.39Å; P487-I491 WeakPolarHBondContact O-CG1 3.22Å; P487-I491 PolarHBondContact O-N 3.5Å; I491-S493 VanDerWaalsContact C-N 3.34Å; I491-S493 PolarHBondContact O-N 3.4Å; I491-A494 PolarHBondContact O-N 3.13Å; I491-V495 HydrophobicContact CG2-CG2 4.07Å; I491-V495 WeakPolarHBondContact O-CB 3.23Å; I491-V495 VanDerWaalsContact O-CG2 3.23Å; I491-V495 WeakPolarHBondContact O-CG2 3.44Å; I491-V495 PolarHBondContact O-N 2.81Å
492	T	95.1	Very high	92.9	Very high	41 Å²	41	41.6 Å²	41.6	25%	0.252	25%	0.251	S	S	.	.	H	α-helix	trans	-60.5	-43.7	178.3	-62.4	0	0	0	0	111.7	S456 A460 F488 A494 V495 V496	S456-T492 WeakPolarHBondContact OG-CG2 3.42Å; A460-T492 HydrophobicContact CB-CG2 3.99Å; F488-T492 VanDerWaalsContact O-CB 3.22Å; F488-T492 WeakPolarHBondContact O-CB 3.09Å; F488-T492 PolarHBondContact O-N 3.4Å; F488-T492 VanDerWaalsContact O-N 3.09Å; F488-T492 PolarHBondContact O-OG1 3.16Å; T492-A494 PolarHBondContact O-N 3.42Å; T492-V495 PolarHBondContact O-N 3.34Å; T492-V496 HydrophobicContact CG2-CG2 4.47Å; T492-V496 VanDerWaalsContact O-CG2 3.27Å; T492-V496 WeakPolarHBondContact O-CG2 3.5Å; T492-V496 PolarHBondContact O-N 2.98Å
493	S	94.3	Very high	92.9	Very high	2 Å²	2	44.1 Å²	44.1	1%	0.014	26%	0.264	C	S	.	.	H	α-helix	trans	-64.2	-41.9	178.2	-59.3	0	0	0	0	112.2	T489 L490 I491 V496 A497	T489-S493 VanDerWaalsContact O-CB 3.31Å; T489-S493 WeakPolarHBondContact O-CB 3.14Å; T489-S493 PolarHBondContact O-N 3.04Å; T489-S493 VanDerWaalsContact O-N 3.14Å; T489-S493 PolarHBondContact O-OG 2.96Å; L490-S493 PolarHBondContact O-N 2.96Å; I491-S493 VanDerWaalsContact C-N 3.34Å; I491-S493 PolarHBondContact O-N 3.4Å; S493-V496 PolarHBondContact O-N 2.88Å; S493-A497 WeakPolarHBondContact O-CB 3.18Å; S493-A497 PolarHBondContact O-N 3.07Å
494	A	94.5	Very high	92.6	Very high	29 Å²	29	51.7 Å²	51.7	24%	0.24	29%	0.289	C	S	.	.	H	α-helix	trans	-65.4	-43.6	176.3	0	0	0	0	0	112.1	F336 L490 I491 T492 A497 G498 M503	F336-A494 HydrophobicContact CE1-CB 4.31Å; F336-A494 HydrophobicContact CZ-CB 4.25Å; L490-A494 WeakPolarHBondContact O-CB 3.5Å; L490-A494 PolarHBondContact O-N 3.4Å; I491-A494 PolarHBondContact O-N 3.13Å; T492-A494 PolarHBondContact O-N 3.42Å; A494-A497 PolarHBondContact O-N 2.83Å; A494-G498 PolarHBondContact O-N 3.5Å; A494-M503 HydrophobicContact CB-CE 4.1Å; A494-M503 WeakPolarHBondContact O-CE 3.12Å
495	V	94.8	Very high	92.3	Very high	82 Å²	82	55.2 Å²	55.2	50%	0.497	31%	0.307	S	S	.	.	H	α-helix	trans	-62.1	-45.2	177.3	169.7	0	0	0	0	110.7	I491 T492 A497 G498 C499	I491-V495 HydrophobicContact CG2-CG2 4.07Å; I491-V495 WeakPolarHBondContact O-CB 3.23Å; I491-V495 VanDerWaalsContact O-CG2 3.23Å; I491-V495 WeakPolarHBondContact O-CG2 3.44Å; I491-V495 PolarHBondContact O-N 2.81Å; T492-V495 PolarHBondContact O-N 3.34Å; V495-A497 VanDerWaalsContact C-N 3.32Å; V495-A497 PolarHBondContact O-N 3.5Å; V495-G498 PolarHBondContact O-N 3.4Å; V495-C499 WeakPolarHBondContact O-CB 3.39Å; V495-C499 PolarHBondContact O-N 2.91Å; V495-C499 PolarHBondContact O-SG 2.91Å
496	V	93.4	Very high	92	Very high	23 Å²	23	55.2 Å²	55.2	14%	0.139	31%	0.307	C	S	.	.	H	α-helix	trans	-59.5	-43.8	176	172.8	0	0	0	0	111.1	V452 Y453 S456 T492 S493 G498 C499 R500	V452-V496 HydrophobicContact CG1-CG1 4.1Å; Y453-V496 HydrophobicContact CD1-CG1 3.92Å; Y453-V496 HydrophobicContact CE1-CB 4.38Å; Y453-V496 HydrophobicContact CE1-CG1 3.76Å; Y453-V496 HydrophobicContact CG-CG1 4.37Å; S456-V496 WeakPolarHBondContact OG-CG2 3.49Å; T492-V496 HydrophobicContact CG2-CG2 4.47Å; T492-V496 VanDerWaalsContact O-CG2 3.27Å; T492-V496 WeakPolarHBondContact O-CG2 3.5Å; T492-V496 PolarHBondContact O-N 2.98Å; S493-V496 PolarHBondContact O-N 2.88Å; V496-G498 VanDerWaalsContact C-N 3.34Å; V496-G498 PolarHBondContact O-N 2.97Å; V496-C499 PolarHBondContact O-N 3.31Å; V496-R500 WeakPolarHBondContact O-CG 3.48Å; V496-R500 PolarHBondContact O-N 3.4Å
497	A	91.7	Very high	91.7	Very high	0 Å²	0	60.4 Å²	60.4	0%	0	33%	0.326	C	S	.	.	H	α-helix	trans	-64.4	-38.1	177	0	0	0	0	0	112.9	Y453 S493 A494 V495 G501 E502 M503 F506	Y453-A497 HydrophobicContact CE1-CB 4.01Å; Y453-A497 WeakPolarHBondContact OH-CA 3.45Å; S493-A497 WeakPolarHBondContact O-CB 3.18Å; S493-A497 PolarHBondContact O-N 3.07Å; A494-A497 PolarHBondContact O-N 2.83Å; V495-A497 VanDerWaalsContact C-N 3.32Å; V495-A497 PolarHBondContact O-N 3.5Å; A497-G501 PolarHBondContact O-N 3.29Å; A497-E502 PolarHBondContact O-N 3.05Å; A497-E502 VanDerWaalsContact O-N 3.11Å; A497-M503 HydrophobicContact CB-CE 3.96Å; A497-M503 HydrophobicContact CB-SD 4.08Å; A497-M503 PolarHBondContact O-N 2.86Å; A497-F506 HydrophobicContact CB-CB 4.01Å; A497-F506 HydrophobicContact CB-CD1 3.58Å; A497-F506 HydrophobicContact CB-CE1 4.21Å; A497-F506 HydrophobicContact CB-CG 3.88Å
498	G	90.9	Very high	91.1	Very high	43 Å²	43	62.3 Å²	62.3	44%	0.443	34%	0.337	S	S	.	.	H	α-helix	trans	-66.4	-48.8	175.9	0	0	0	0	0	112.3	A494 V495 V496 R500 G501	A494-G498 PolarHBondContact O-N 3.5Å; V495-G498 PolarHBondContact O-N 3.4Å; V496-G498 VanDerWaalsContact C-N 3.34Å; V496-G498 PolarHBondContact O-N 2.97Å; G498-R500 PolarHBondContact O-N 3.12Å; G498-G501 PolarHBondContact O-N 3.11Å
499	C	92	Very high	90	Very high	109 Å²	109	59.1 Å²	59.1	74%	0.736	32%	0.324	S	S	*	.	H	α-helix	trans	-61.4	-27.3	179	-68.9	0	0	0	0	113.3	V495 V496	V495-C499 WeakPolarHBondContact O-CB 3.39Å; V495-C499 PolarHBondContact O-N 2.91Å; V495-C499 PolarHBondContact O-SG 2.91Å; V496-C499 PolarHBondContact O-N 3.31Å
500	R	89.3	Confident	88.2	Confident	94 Å²	94	61.3 Å²	61.3	36%	0.355	34%	0.337	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.8	-7.8	177.2	-68.4	-178	62.9	132.2	2.4	114.1	V496 G498 E502	V496-R500 WeakPolarHBondContact O-CG 3.48Å; V496-R500 PolarHBondContact O-N 3.4Å; G498-R500 PolarHBondContact O-N 3.12Å; R500-E502 HydrophobicContact CB-CB 4.4Å; R500-E502 HydrophobicContact CB-CG 4.14Å; R500-E502 IonicContact CZ-OE1 2.71Å; R500-E502 IonicContact CZ-OE2 3.74Å; R500-E502 IonicContact NE-OE1 3.02Å; R500-E502 PolarHBondContact NE-OE1 3.25Å; R500-E502 IonicContact NE-OE2 3.76Å; R500-E502 PolarHBondContact NE-OE2 3.28Å; R500-E502 IonicContact NH2-OE1 3.2Å; R500-E502 PolarHBondContact NH2-OE1 3.17Å; R500-E502 IonicContact NH2-OE2 3.58Å; R500-E502 PolarHBondContact O-N 2.86Å
501	G	87.1	Confident	85.8	Confident	67 Å²	67	65.7 Å²	65.7	69%	0.691	37%	0.365	S	S	*	.	T	Hydrogen-bonded Turn	trans	70	8.9	-173.8	0	0	0	0	0	114.3	A497 G498	A497-G501 PolarHBondContact O-N 3.29Å; G498-G501 PolarHBondContact O-N 3.11Å
502	E	89.3	Confident	83.3	Confident	33 Å²	33	70.5 Å²	70.5	15%	0.154	38%	0.378	C	S	.	.			trans	-93.2	5.9	-176.4	-67.4	166.8	-160.9	0	0	112.1	Y453 A497 R500 R504 Q505 F506	Y453-E502 WeakPolarHBondContact CE2-OE2 3.27Å; Y453-E502 PolarHBondContact OH-OE2 3.37Å; A497-E502 PolarHBondContact O-N 3.05Å; A497-E502 VanDerWaalsContact O-N 3.11Å; R500-E502 HydrophobicContact CB-CB 4.4Å; R500-E502 HydrophobicContact CB-CG 4.14Å; R500-E502 IonicContact CZ-OE1 2.71Å; R500-E502 IonicContact CZ-OE2 3.74Å; R500-E502 IonicContact NE-OE1 3.02Å; R500-E502 PolarHBondContact NE-OE1 3.25Å; R500-E502 IonicContact NE-OE2 3.76Å; R500-E502 PolarHBondContact NE-OE2 3.28Å; R500-E502 IonicContact NH2-OE1 3.2Å; R500-E502 PolarHBondContact NH2-OE1 3.17Å; R500-E502 IonicContact NH2-OE2 3.58Å; R500-E502 PolarHBondContact O-N 2.86Å; E502-R504 VanDerWaalsContact C-N 3.29Å; E502-R504 PolarHBondContact O-N 3.2Å; E502-Q505 PolarHBondContact O-N 3.26Å; E502-Q505 VanDerWaalsContact O-N 3.13Å; E502-F506 WeakPolarHBondContact O-CB 3.47Å; E502-F506 PolarHBondContact O-N 2.9Å
503	M	89.4	Confident	80.9	Confident	63 Å²	63	72 Å²	72	31%	0.31	38%	0.382	S	S	.	.	H	α-helix	trans	-52.2	-41.5	-174.7	-179.2	60.3	80.3	0	0	113.7	A494 A497 Q505 F506 W507	A494-M503 HydrophobicContact CB-CE 4.1Å; A494-M503 WeakPolarHBondContact O-CE 3.12Å; A497-M503 HydrophobicContact CB-CE 3.96Å; A497-M503 HydrophobicContact CB-SD 4.08Å; A497-M503 PolarHBondContact O-N 2.86Å; M503-Q505 PolarHBondContact O-N 3.28Å; M503-F506 PolarHBondContact O-N 3.32Å; M503-W507 WeakPolarHBondContact O-CB 3.19Å; M503-W507 PolarHBondContact O-N 3.33Å
504	R	86.2	Confident	78.2	Confident	215 Å²	215	76.6 Å²	76.6	81%	0.811	41%	0.41	S	S	*	.	H	α-helix	trans	-63	-46.2	-178.9	-173.2	174.7	173.8	170.6	-1.9	111.5	E502 W507 T508	E502-R504 VanDerWaalsContact C-N 3.29Å; E502-R504 PolarHBondContact O-N 3.2Å; R504-W507 PolarHBondContact O-N 3.5Å; R504-T508 PolarHBondContact O-N 3.17Å; R504-T508 VanDerWaalsContact O-N 3.13Å; R504-T508 PolarHBondContact O-OG1 3.25Å
505	Q	85.6	Confident	75.5	Confident	119 Å²	119	81.2 Å²	81.2	56%	0.556	43%	0.43	S	S	*	.	H	α-helix	trans	-68.1	-38.4	177.3	-65.7	176	-5.2	0	0	111.4	F442 E502 M503 G509	F442-Q505 HydrophobicContact CZ-CB 4.48Å; E502-Q505 PolarHBondContact O-N 3.26Å; E502-Q505 VanDerWaalsContact O-N 3.13Å; M503-Q505 PolarHBondContact O-N 3.28Å; Q505-G509 CarbonylContact O-C 3.53Å; Q505-G509 WeakPolarHBondContact O-CA 3.41Å; Q505-G509 PolarHBondContact O-N 3.11Å
506	F	88.7	Confident	72.8	Confident	0 Å²	0	83.7 Å²	83.7	0%	0	44%	0.44	C	S	.	.	H	α-helix	trans	-64.6	-40.8	176	-168.6	-115.3	0	0	0	111.8	F336 Y438 F442 Y453 A497 E502 M503	F336-F506 HydrophobicContact CB-CD1 3.89Å; F336-F506 HydrophobicContact CB-CE1 3.94Å; F336-F506 HydrophobicContact CB-CG 4.36Å; F336-F506 HydrophobicContact CB-CZ 4.42Å; F336-F506 WeakPolarHBondContact CB-O 3.34Å; F336-F506 AromaticContact CD1-CD1 3.74Å; F336-F506 HydrophobicContact CD1-CD1 3.74Å; F336-F506 AromaticContact CD1-CE1 3.69Å; F336-F506 HydrophobicContact CD1-CE1 3.69Å; F336-F506 HydrophobicContact CD2-CD1 4.02Å; F336-F506 AromaticContact CD2-CE1 3.23Å; F336-F506 HydrophobicContact CD2-CE1 3.23Å; F336-F506 AromaticContact CD2-CZ 3.61Å; F336-F506 HydrophobicContact CD2-CZ 3.61Å; F336-F506 HydrophobicContact CE1-CD1 4.24Å; F336-F506 AromaticContact CE1-CE1 3.93Å; F336-F506 HydrophobicContact CE1-CE1 3.93Å; F336-F506 HydrophobicContact CE2-CD1 4.49Å; F336-F506 AromaticContact CE2-CE1 3.5Å; F336-F506 HydrophobicContact CE2-CE1 3.5Å; F336-F506 HydrophobicContact CE2-CZ 4.01Å; F336-F506 AromaticContact CG-CD1 3.62Å; F336-F506 HydrophobicContact CG-CD1 3.62Å; F336-F506 AromaticContact CG-CE1 3.33Å; F336-F506 HydrophobicContact CG-CE1 3.33Å; F336-F506 HydrophobicContact CG-CZ 4.04Å; F336-F506 AromaticContact CZ-CE1 3.84Å; F336-F506 HydrophobicContact CZ-CE1 3.84Å; F336-F506 PolarHBondContact N-O 3.39Å; Y438-F506 HydrophobicContact CD1-CE2 4.04Å; Y438-F506 HydrophobicContact CD1-CZ 4.22Å; Y438-F506 AromaticContact CE1-CD2 3.9Å; Y438-F506 HydrophobicContact CE1-CD2 3.9Å; Y438-F506 AromaticContact CE1-CE2 3.43Å; Y438-F506 HydrophobicContact CE1-CE2 3.43Å; Y438-F506 VanDerWaalsContact CE1-CE2 3.43Å; Y438-F506 AromaticContact CE1-CZ 3.81Å; Y438-F506 HydrophobicContact CE1-CZ 3.81Å; Y438-F506 PolarHBondContact OH-O 3.36Å; F442-F506 HydrophobicContact CB-CD2 4.5Å; F442-F506 HydrophobicContact CB-CE2 4.37Å; F442-F506 AromaticContact CD1-CD2 3.63Å; F442-F506 HydrophobicContact CD1-CD2 3.63Å; F442-F506 HydrophobicContact CD1-CE2 4.02Å; F442-F506 AromaticContact CD2-CD2 3.8Å; F442-F506 HydrophobicContact CD2-CD2 3.8Å; F442-F506 HydrophobicContact CD2-CE2 4.45Å; F442-F506 HydrophobicContact CE1-CB 4.38Å; F442-F506 AromaticContact CE1-CD2 3.67Å; F442-F506 HydrophobicContact CE1-CD2 3.67Å; F442-F506 HydrophobicContact CE1-CE2 4.46Å; F442-F506 HydrophobicContact CE1-CG 4.47Å; F442-F506 HydrophobicContact CE2-CB 4.18Å; F442-F506 AromaticContact CE2-CD2 3.87Å; F442-F506 HydrophobicContact CE2-CD2 3.87Å; F442-F506 AromaticContact CG-CD2 3.7Å; F442-F506 HydrophobicContact CG-CD2 3.7Å; F442-F506 HydrophobicContact CG-CE2 4.02Å; F442-F506 HydrophobicContact CZ-CB 3.9Å; F442-F506 AromaticContact CZ-CD2 3.8Å; F442-F506 HydrophobicContact CZ-CD2 3.8Å; F442-F506 HydrophobicContact CZ-CG 4.36Å; Y453-F506 HydrophobicContact CD1-CD2 4.41Å; Y453-F506 AromaticContact CD1-CE2 3.9Å; Y453-F506 HydrophobicContact CD1-CE2 3.9Å; Y453-F506 HydrophobicContact CD1-CZ 4.27Å; Y453-F506 HydrophobicContact CE1-CD2 4.09Å; Y453-F506 HydrophobicContact CE1-CE2 4.01Å; Y453-F506 HydrophobicContact CE1-CZ 4.42Å; A497-F506 HydrophobicContact CB-CB 4.01Å; A497-F506 HydrophobicContact CB-CD1 3.58Å; A497-F506 HydrophobicContact CB-CE1 4.21Å; A497-F506 HydrophobicContact CB-CG 3.88Å; E502-F506 WeakPolarHBondContact O-CB 3.47Å; E502-F506 PolarHBondContact O-N 2.9Å; M503-F506 PolarHBondContact O-N 3.32Å
507	W	88.1	Confident	69.9	Low	111 Å²	111	87.6 Å²	87.6	42%	0.42	47%	0.469	S	S	.	.	H	α-helix	trans	-69.6	-47.4	-177.9	-170.9	-95	0	0	0	113.4	F336 K337 V340 M503 R504	F336-W507 AromaticContact CD1-CE3 3.67Å; F336-W507 HydrophobicContact CD1-CE3 3.67Å; F336-W507 AromaticContact CD1-CZ3 3.94Å; F336-W507 HydrophobicContact CD1-CZ3 3.94Å; F336-W507 HydrophobicContact CE1-CE3 4.13Å; F336-W507 HydrophobicContact CE1-CZ3 4.03Å; K337-W507 HydrophobicContact CB-CZ2 4.4Å; K337-W507 HydrophobicContact CG-CZ2 4.3Å; K337-W507 PolarHBondContact N-O 3.13Å; V340-W507 HydrophobicContact CG2-CH2 4.27Å; V340-W507 HydrophobicContact CG2-CZ3 4.04Å; M503-W507 WeakPolarHBondContact O-CB 3.19Å; M503-W507 PolarHBondContact O-N 3.33Å; R504-W507 PolarHBondContact O-N 3.5Å
508	T	81.4	Confident	67.1	Low	85 Å²	85	91.9 Å²	91.9	52%	0.521	50%	0.499	S	S	.	.	H	α-helix	trans	-87.8	-7.3	-176.8	59.6	0	0	0	0	114.1	N335 R504	N335-T508 PolarHBondContact OD1-O 2.98Å; R504-T508 PolarHBondContact O-N 3.17Å; R504-T508 VanDerWaalsContact O-N 3.13Å; R504-T508 PolarHBondContact O-OG1 3.25Å
509	G	71.4	Confident	64.5	Low	4 Å²	4	99.4 Å²	99.4	4%	0.041	51%	0.514	C	S	.	.			trans	63.3	-173.9	-167.8	0	0	0	0	0	112.8	N335 Q505	N335-G509 WeakPolarHBondContact OD1-CA 3.01Å; N335-G509 PolarHBondContact OD1-N 3.38Å; Q505-G509 CarbonylContact O-C 3.53Å; Q505-G509 WeakPolarHBondContact O-CA 3.41Å; Q505-G509 PolarHBondContact O-N 3.11Å
510	T	58.9	Low	61.4	Low	45 Å²	45	102.5 Å²	102.5	28%	0.276	52%	0.517	S	S	.	.			trans	-81.4	142.8	-174.9	57.5	0	0	0	0	112.2	W445 Y512	W445-T510 HydrophobicContact CB-CG2 3.97Å; W445-T510 HydrophobicContact CD2-CG2 3.8Å; W445-T510 HydrophobicContact CE3-CG2 3.55Å; W445-T510 HydrophobicContact CG-CG2 4.02Å; W445-T510 HydrophobicContact CZ3-CG2 4.25Å; T510-Y512 PolarHBondContact O-N 3.29Å
511	T	44.6	Very low	58.7	Low	110 Å²	110	103.5 Å²	103.5	68%	0.675	54%	0.536	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.8	-9.7	-177.5	-43.1	0	0	0	0	114.9	E513 V514	T511-E513 VanDerWaalsContact C-N 3.25Å; T511-E513 PolarHBondContact O-N 3.5Å; T511-V514 PolarHBondContact O-N 2.85Å
512	Y	43.2	Very low	56.1	Low	206 Å²	206	108.2 Å²	108.2	81%	0.808	55%	0.545	S	S	*	.	H	α-helix	trans	-64.2	-25.8	-179.1	-81	-84.3	0	0	0	113.4	T510	T510-Y512 PolarHBondContact O-N 3.29Å
513	E	43.9	Very low	53.6	Low	73 Å²	73	114 Å²	114	34%	0.341	58%	0.576	S	S	.	*	H	α-helix	trans	-86.7	-16.8	179.2	-70.5	-174	172.3	0	0	114.2	S334 T511 L515 D516 S517	S334-E513 WeakPolarHBondContact CB-OE2 3.19Å; T511-E513 VanDerWaalsContact C-N 3.25Å; T511-E513 PolarHBondContact O-N 3.5Å; E513-L515 VanDerWaalsContact C-N 3.25Å; E513-L515 PolarHBondContact O-N 3.49Å; E513-D516 PolarHBondContact O-N 2.86Å; E513-S517 PolarHBondContact O-N 3.26Å
514	V	38.4	Very low	51	Low	97 Å²	97	116.9 Å²	116.9	59%	0.588	60%	0.599	S	S	*	*	H	α-helix	trans	-72	-24.8	176.1	-177.5	0	0	0	0	111	T511 S518	T511-V514 PolarHBondContact O-N 2.85Å; V514-S518 PolarHBondContact O-OG 3.2Å
515	L	38.3	Very low	48.4	Very low	126 Å²	126	115.6 Å²	115.6	66%	0.66	60%	0.602	S	S	*	*	H	α-helix	trans	-75.5	-33.6	176.5	-118.9	86	0	0	0	113.2	E513 S518	E513-L515 VanDerWaalsContact C-N 3.25Å; E513-L515 PolarHBondContact O-N 3.49Å; L515-S518 PolarHBondContact O-N 3.19Å
516	D	36.8	Very low	45.9	Very low	134 Å²	134	113.9 Å²	113.9	72%	0.717	62%	0.616	S	S	*	*	H	α-helix	trans	-74.9	-28.2	179.7	-105.6	-8.7	0	0	0	112.4	E513 S518	E513-D516 PolarHBondContact O-N 2.86Å; D516-S518 PolarHBondContact O-N 3.4Å
517	S	33.1	Very low	43.1	Very low	105 Å²	105	124.7 Å²	124.7	73%	0.734	66%	0.657	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.2	-13.1	173.2	-172.9	0	0	0	0	113.6	E513	E513-S517 PolarHBondContact O-N 3.26Å
518	S	32.9	Very low	40.6	Very low	91 Å²	91	125.7 Å²	125.7	64%	0.636	68%	0.676	S	S	*	*	T	Hydrogen-bonded Turn	trans	-100.6	5.6	-173.4	-57.2	0	0	0	0	114	V514 L515 D516	V514-S518 PolarHBondContact O-OG 3.2Å; L515-S518 PolarHBondContact O-N 3.19Å; D516-S518 PolarHBondContact O-N 3.4Å
519	R	35.2	Very low	38.2	Very low	201 Å²	201	128.9 Å²	128.9	76%	0.758	69%	0.689	S	S	*	*			trans	-108.2	67.5	174.5	-74.7	-175.4	173.7	170.3	-1.6	111.1
520	E	28.1	Very low	36.2	Very low	174 Å²	174	140 Å²	140	81%	0.813	73%	0.73	S	S	*	*			trans	-73	122.7	143.4	-83.5	-166.5	138.4	0	0	107.3	L522	E520-L522 PolarHBondContact O-N 3.28Å
521	P	32.8	Very low	34.8	Very low	115 Å²	115	143 Å²	143	75%	0.747	75%	0.752	S	S	*	*			trans	-69.7	103.7	169.5	27	-28.5	0	0	0	107.8	L523	P521-L523 VanDerWaalsContact C-N 3.33Å; P521-L523 PolarHBondContact O-N 2.84Å
522	L	32	Very low	34.2	Very low	166 Å²	166	146.1 Å²	146.1	87%	0.869	76%	0.763	S	S	*	*			trans	-59	101.9	159.3	-73.4	168.6	0	0	0	107.1	E520	E520-L522 PolarHBondContact O-N 3.28Å
523	L	35.7	Very low	33.5	Very low	154 Å²	154	139.1 Å²	139.1	81%	0.806	75%	0.754	S	S	*	*	P	Polyproline II helix	trans	-54.7	130.2	163	-70.7	170.3	0	0	0	107.7	P521 E525	P521-L523 VanDerWaalsContact C-N 3.33Å; P521-L523 PolarHBondContact O-N 2.84Å; L523-E525 PolarHBondContact O-N 3.02Å
524	P	35.2	Very low	32.8	Very low	123 Å²	123	145.3 Å²	145.3	80%	0.799	78%	0.783	S	S	*	*	P	Polyproline II helix	trans	-69.3	121.6	171.4	26.6	-27.8	0	0	0	108.2	G526	P524-G526 PolarHBondContact O-N 3.28Å
525	E	31.3	Very low	32.4	Very low	189 Å²	189	145.7 Å²	145.7	88%	0.883	79%	0.79	S	S	*	*	P	Polyproline II helix	trans	-48.2	128.5	167.7	-92.7	178.2	135.4	0	0	110	L523 R527	L523-E525 PolarHBondContact O-N 3.02Å; E525-R527 PolarHBondContact O-N 3.04Å
526	G	34	Very low	32.2	Very low	82 Å²	82	149.3 Å²	149.3	85%	0.845	82%	0.823	S	S	*	*	P	Polyproline II helix	trans	-57.9	121.7	168.4	0	0	0	0	0	109.9	P524	P524-G526 PolarHBondContact O-N 3.28Å
527	R	29.8	Very low	31.9	Very low	228 Å²	228	150.1 Å²	150.1	86%	0.86	83%	0.829	S	S	*	*			trans	-115.4	101.4	159.1	-150.7	174.4	-163.6	140.9	3.2	107.9	E525 D529	E525-R527 PolarHBondContact O-N 3.04Å; R527-D529 PolarHBondContact O-N 3.21Å
528	T	36	Very low	31.9	Very low	132 Å²	132	152.5 Å²	152.5	81%	0.81	83%	0.834	S	S	*	*			trans	-48.4	118.6	153.2	31.5	0	0	0	0	109.2
529	D	29.7	Very low	31.8	Very low	151 Å²	151	155.9 Å²	155.9	81%	0.807	85%	0.845	S	S	*	*			trans	-148.6	131	141.2	-95	-35	0	0	0	110.9	R527	R527-D529 PolarHBondContact O-N 3.21Å
530	R	30.1	Very low	31.6	Very low	239 Å²	239	153.2 Å²	153.2	90%	0.902	85%	0.85	S	S	*	*			trans	-71.4	142.6	174.3	-76.3	167.4	157.8	170.8	-6.8	110.4
531	S	28.8	Very low	31.8	Very low	106 Å²	106	151.9 Å²	151.9	74%	0.741	85%	0.852	S	S	*	*				166.2	115	127.9	40.1	0	0	0	0	109.8
532	I	32.1	Very low	31.8	Very low	177 Å²	177	154.4 Å²	154.4	91%	0.908	86%	0.859	S	S	*	*				77.9	126.9	99	-65	166.1	0	0	0	114.3
533	G	28.6	Very low	31.7	Very low	59 Å²	59	153.6 Å²	153.6	61%	0.608	86%	0.858	S	S	*	*			trans	115.7	100.7	160.9	0	0	0	0	0	112.9
534	E	29.8	Very low	31.4	Very low	203 Å²	203	153.5 Å²	153.5	95%	0.949	86%	0.862	S	S	*	*				64.8	134.7	96.4	-73.6	-176	154.4	0	0	112.5
535	S	30.2	Very low	31.1	Very low	105 Å²	105	156.1 Å²	156.1	73%	0.734	87%	0.868	S	S	*	*			cis	-173.9	155.1	-1.9	178.1	0	0	0	0	104.7
536	C	33	Very low	31.1	Very low	202 Å²	202	153.1 Å²	153.1	100%	1.365	87%	0.866	S	S	*	*			trans	76.8	0	169.1	-65.1	0	0	0	0	118.9

Retrieved 536 of 536 residues in 300.3 ms (Link to these results)

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