A0A087YH68_POEFO Loading...

Polyprenal reductase

Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol. Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).

AlphaFold DB , UniProt , Accession A0A087YH68, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 313 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	S	72.8	Confident	92.7	Very high	167 Å²	167	60.5 Å²	60.5	100%	1.168	35%	0.35	S	S	*	.				0	148.6	0	35.4	0	0	0	0	108.6
2	L	86.4	Confident	93	Very high	86 Å²	86	58.5 Å²	58.5	45%	0.45	34%	0.337	S	S	.	.			trans	-69	140.1	168	-69.3	171	0	0	0	108.4	D6 L10 F270	L2-D6 HydrophobicContact CB-CB 4.14Å; L2-D6 HydrophobicContact CD2-CB 3.96Å; L2-L10 HydrophobicContact CD1-CD2 4.03Å; L2-F270 HydrophobicContact CD2-CE1 3.52Å; L2-F270 HydrophobicContact CD2-CZ 4.03Å
3	S	92	Very high	93.3	Very high	15 Å²	15	54 Å²	54	11%	0.105	31%	0.311	C	S	.	.			trans	-69.6	169.5	170.4	65.9	0	0	0	0	110.6	I5 D6 S7 T111	S3-I5 VanDerWaalsContact C-N 3.3Å; S3-I5 PolarHBondContact O-N 3.42Å; S3-I5 WeakPolarHBondContact OG-CG2 3.25Å; S3-D6 WeakPolarHBondContact CB-OD2 3.41Å; S3-D6 PolarHBondContact N-OD2 3.35Å; S3-D6 PolarHBondContact O-N 2.88Å; S3-D6 PolarHBondContact OG-N 2.92Å; S3-D6 PolarHBondContact OG-OD2 2.86Å; S3-S7 WeakPolarHBondContact O-CB 3.49Å; S3-S7 PolarHBondContact O-N 3.21Å; S3-S7 PolarHBondContact O-OG 2.63Å; S3-T111 VanDerWaalsContact CB-O 3.27Å; S3-T111 WeakPolarHBondContact CB-O 3.3Å
4	L	94.6	Very high	93.6	Very high	86 Å²	86	56.4 Å²	56.4	45%	0.45	32%	0.322	S	S	.	.	H	α-helix	trans	-61.3	-43.3	175	178.9	62.8	0	0	0	110.3	D6 S7 C8 I109 L110	L4-D6 PolarHBondContact O-N 3.09Å; L4-S7 PolarHBondContact O-N 3.1Å; L4-C8 PolarHBondContact O-N 3.44Å; L4-C8 PolarHBondContact O-SG 3.41Å; L4-I109 HydrophobicContact CD2-CG2 3.95Å; L4-L110 HydrophobicContact CD2-CD2 4.45Å; L4-L110 PolarHBondContact N-O 3.25Å
5	I	94.9	Very high	93.7	Very high	2 Å²	2	56.1 Å²	56.1	1%	0.01	32%	0.323	C	S	.	.	H	α-helix	trans	-64.4	-39.3	179.3	-168.7	59.6	0	0	0	112.3	S3 C8 W9 L110 V172 T176 T271	S3-I5 VanDerWaalsContact C-N 3.3Å; S3-I5 PolarHBondContact O-N 3.42Å; S3-I5 WeakPolarHBondContact OG-CG2 3.25Å; I5-C8 PolarHBondContact O-N 2.84Å; I5-W9 PolarHBondContact O-N 3.42Å; I5-W9 VanDerWaalsContact O-N 3.07Å; I5-L110 HydrophobicContact CB-CB 4.26Å; I5-L110 HydrophobicContact CD1-CD2 4.37Å; I5-L110 WeakPolarHBondContact CG2-O 3.15Å; I5-L110 PolarHBondContact N-O 3.34Å; I5-V172 HydrophobicContact CD1-CG1 3.81Å; I5-T176 HydrophobicContact CG1-CG2 4.33Å; I5-T271 HydrophobicContact CG1-CG2 4.07Å; I5-T271 HydrophobicContact CG2-CG2 3.9Å
6	D	94.9	Very high	93.8	Very high	13 Å²	13	55.4 Å²	55.4	7%	0.07	32%	0.315	C	S	.	.	H	α-helix	trans	-62.2	-45.6	173.7	-61.8	-40.3	0	0	0	111	L2 S3 L4 C8 W9 L10 F270 T271 L274	L2-D6 HydrophobicContact CB-CB 4.14Å; L2-D6 HydrophobicContact CD2-CB 3.96Å; S3-D6 WeakPolarHBondContact CB-OD2 3.41Å; S3-D6 PolarHBondContact N-OD2 3.35Å; S3-D6 PolarHBondContact O-N 2.88Å; S3-D6 PolarHBondContact OG-N 2.92Å; S3-D6 PolarHBondContact OG-OD2 2.86Å; L4-D6 PolarHBondContact O-N 3.09Å; D6-C8 VanDerWaalsContact C-N 3.32Å; D6-C8 PolarHBondContact O-N 3.38Å; D6-W9 PolarHBondContact O-N 3.47Å; D6-L10 VanDerWaalsContact O-CB 3.29Å; D6-L10 WeakPolarHBondContact O-CB 3.13Å; D6-L10 PolarHBondContact O-N 3.31Å; D6-F270 HydrophobicContact CB-CE1 4.37Å; D6-T271 WeakPolarHBondContact OD1-CA 3.44Å; D6-T271 WeakPolarHBondContact OD1-CB 3.47Å; D6-T271 WeakPolarHBondContact OD1-CG2 3.49Å; D6-T271 PolarHBondContact OD1-OG1 2.98Å; D6-L274 HydrophobicContact CB-CD1 3.81Å; D6-L274 WeakPolarHBondContact O-CD1 3.35Å
7	S	96.2	Very high	93.9	Very high	50 Å²	50	55.4 Å²	55.4	35%	0.35	31%	0.314	S	S	.	.	H	α-helix	trans	-62.8	-40.4	-179.6	-56.9	0	0	0	0	111.4	S3 L4 F11	S3-S7 WeakPolarHBondContact O-CB 3.49Å; S3-S7 PolarHBondContact O-N 3.21Å; S3-S7 PolarHBondContact O-OG 2.63Å; L4-S7 PolarHBondContact O-N 3.1Å; S7-F11 WeakPolarHBondContact O-CB 3.48Å; S7-F11 PolarHBondContact O-N 3.37Å
8	C	96	Very high	93.9	Very high	53 Å²	53	57.3 Å²	57.3	36%	0.358	33%	0.327	S	S	.	.	H	α-helix	trans	-61.8	-50.2	175.1	-71.2	0	0	0	0	112.1	L4 I5 D6 F11 L12	L4-C8 PolarHBondContact O-N 3.44Å; L4-C8 PolarHBondContact O-SG 3.41Å; I5-C8 PolarHBondContact O-N 2.84Å; D6-C8 VanDerWaalsContact C-N 3.32Å; D6-C8 PolarHBondContact O-N 3.38Å; C8-F11 PolarHBondContact O-N 2.86Å; C8-L12 WeakPolarHBondContact O-CG 3.44Å; C8-L12 PolarHBondContact O-N 3.23Å
9	W	97.5	Very high	93.8	Very high	3 Å²	3	54.8 Å²	54.8	1%	0.011	31%	0.314	C	S	.	.	H	α-helix	trans	-66.7	-40.3	-179.6	-74.4	121.4	0	0	0	112.8	I5 D6 L12 A13 Y169 V172 T176 L274 V275 Y278	I5-W9 PolarHBondContact O-N 3.42Å; I5-W9 VanDerWaalsContact O-N 3.07Å; D6-W9 PolarHBondContact O-N 3.47Å; W9-L12 HydrophobicContact CE3-CD1 3.96Å; W9-L12 HydrophobicContact CZ3-CD1 4.01Å; W9-L12 PolarHBondContact O-N 3.43Å; W9-A13 WeakPolarHBondContact O-CB 3.23Å; W9-A13 PolarHBondContact O-N 2.93Å; W9-Y169 AromaticContact CH2-CD2 3.69Å; W9-Y169 HydrophobicContact CH2-CD2 3.69Å; W9-Y169 AromaticContact CH2-CE2 3.42Å; W9-Y169 HydrophobicContact CH2-CE2 3.42Å; W9-Y169 VanDerWaalsContact CH2-CE2 3.42Å; W9-Y169 AromaticContact CZ3-CD2 3.98Å; W9-Y169 HydrophobicContact CZ3-CD2 3.98Å; W9-Y169 AromaticContact CZ3-CE2 3.64Å; W9-Y169 HydrophobicContact CZ3-CE2 3.64Å; W9-V172 HydrophobicContact CH2-CG1 4.44Å; W9-V172 HydrophobicContact CZ2-CG1 3.76Å; W9-T176 PolarHBondContact NE1-OG1 3.46Å; W9-L274 HydrophobicContact CB-CB 3.68Å; W9-V275 HydrophobicContact CD2-CG2 3.82Å; W9-V275 HydrophobicContact CE3-CG2 4.42Å; W9-V275 HydrophobicContact CG-CG2 4.04Å; W9-V275 HydrophobicContact CH2-CG1 4.48Å; W9-V275 HydrophobicContact CZ2-CG2 4.07Å; W9-Y278 HydrophobicContact CE3-CD1 4.13Å; W9-Y278 HydrophobicContact CE3-CG 4.09Å; W9-Y278 AromaticContact CZ3-CD1 3.7Å; W9-Y278 HydrophobicContact CZ3-CD1 3.7Å; W9-Y278 HydrophobicContact CZ3-CE1 4.1Å; W9-Y278 HydrophobicContact CZ3-CG 4.07Å
10	L	97.4	Very high	93.7	Very high	54 Å²	54	53.3 Å²	53.3	28%	0.283	30%	0.304	S	S	.	.	H	α-helix	trans	-62.6	-45.9	175.2	180	60.7	0	0	0	111.2	L2 D6 L12 A13 L14 L274	L2-L10 HydrophobicContact CD1-CD2 4.03Å; D6-L10 VanDerWaalsContact O-CB 3.29Å; D6-L10 WeakPolarHBondContact O-CB 3.13Å; D6-L10 PolarHBondContact O-N 3.31Å; L10-L12 VanDerWaalsContact C-N 3.34Å; L10-L12 PolarHBondContact O-N 3.48Å; L10-A13 PolarHBondContact O-N 3.19Å; L10-L14 HydrophobicContact CD1-CD1 4.27Å; L10-L14 HydrophobicContact CD1-CG 4.25Å; L10-L14 HydrophobicContact CG-CD1 4.12Å; L10-L14 VanDerWaalsContact O-CG 3.31Å; L10-L14 WeakPolarHBondContact O-CG 3.45Å; L10-L14 PolarHBondContact O-N 2.97Å; L10-L274 HydrophobicContact CB-CD1 4.29Å; L10-L274 HydrophobicContact CB-CD2 4.3Å; L10-L274 HydrophobicContact CD1-CD2 4.12Å
11	F	96.9	Very high	93.5	Very high	136 Å²	136	53.6 Å²	53.6	60%	0.596	31%	0.309	S	S	*	.	H	α-helix	trans	-57	-48.1	175.9	174.3	-101.1	0	0	0	111.3	S7 C8 A13 L14 C15	S7-F11 WeakPolarHBondContact O-CB 3.48Å; S7-F11 PolarHBondContact O-N 3.37Å; C8-F11 PolarHBondContact O-N 2.86Å; F11-A13 PolarHBondContact O-N 3.34Å; F11-L14 PolarHBondContact O-N 2.83Å; F11-C15 WeakPolarHBondContact CZ-SG 3.34Å; F11-C15 PolarHBondContact O-N 2.97Å; F11-C15 PolarHBondContact O-SG 3.23Å
12	L	96.4	Very high	94.3	Very high	37 Å²	37	48.6 Å²	48.6	19%	0.194	27%	0.271	C	S	.	.	H	α-helix	trans	-61.1	-45.5	177.4	-70.5	175.4	0	0	0	112.2	C8 W9 L10 L14 C15 F16 F165 Y278	C8-L12 WeakPolarHBondContact O-CG 3.44Å; C8-L12 PolarHBondContact O-N 3.23Å; W9-L12 HydrophobicContact CE3-CD1 3.96Å; W9-L12 HydrophobicContact CZ3-CD1 4.01Å; W9-L12 PolarHBondContact O-N 3.43Å; L10-L12 VanDerWaalsContact C-N 3.34Å; L10-L12 PolarHBondContact O-N 3.48Å; L12-L14 VanDerWaalsContact C-N 3.33Å; L12-L14 PolarHBondContact O-N 2.72Å; L12-C15 PolarHBondContact O-N 3.21Å; L12-F16 WeakPolarHBondContact O-CD2 3.4Å; L12-F16 PolarHBondContact O-N 2.89Å; L12-F16 VanDerWaalsContact O-N 3.09Å; L12-F165 HydrophobicContact CD1-CE2 4.24Å; L12-F165 HydrophobicContact CD1-CZ 4.25Å; L12-F165 HydrophobicContact CD2-CE2 3.65Å; L12-F165 HydrophobicContact CD2-CZ 3.98Å; L12-Y278 HydrophobicContact CB-CD2 3.65Å; L12-Y278 HydrophobicContact CB-CE2 4.11Å; L12-Y278 HydrophobicContact CB-CG 4.43Å
13	A	97.4	Very high	94.4	Very high	0 Å²	0	44.8 Å²	44.8	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-58.1	-45.7	176.8	0	0	0	0	0	111.6	W9 L10 F11 F16 L17 L277 F281	W9-A13 WeakPolarHBondContact O-CB 3.23Å; W9-A13 PolarHBondContact O-N 2.93Å; L10-A13 PolarHBondContact O-N 3.19Å; F11-A13 PolarHBondContact O-N 3.34Å; A13-F16 PolarHBondContact O-N 3.2Å; A13-L17 WeakPolarHBondContact O-CB 3.46Å; A13-L17 PolarHBondContact O-N 3.36Å; A13-L277 HydrophobicContact CB-CB 4.4Å; A13-L277 HydrophobicContact CB-CD2 4.12Å; A13-L277 HydrophobicContact CB-CG 4.03Å; A13-F281 HydrophobicContact CB-CD2 4.18Å; A13-F281 VanDerWaalsContact O-CD2 3.27Å; A13-F281 WeakPolarHBondContact O-CD2 3.1Å
14	L	97.4	Very high	94.1	Very high	88 Å²	88	48.7 Å²	48.7	46%	0.461	27%	0.266	S	S	.	.	H	α-helix	trans	-63.8	-42.3	177.4	-69.1	174	0	0	0	112.1	L10 F11 L12 F16 L17 V18	L10-L14 HydrophobicContact CD1-CD1 4.27Å; L10-L14 HydrophobicContact CD1-CG 4.25Å; L10-L14 HydrophobicContact CG-CD1 4.12Å; L10-L14 VanDerWaalsContact O-CG 3.31Å; L10-L14 WeakPolarHBondContact O-CG 3.45Å; L10-L14 PolarHBondContact O-N 2.97Å; F11-L14 PolarHBondContact O-N 2.83Å; L12-L14 VanDerWaalsContact C-N 3.33Å; L12-L14 PolarHBondContact O-N 2.72Å; L14-F16 VanDerWaalsContact C-N 3.33Å; L14-F16 PolarHBondContact O-N 3.46Å; L14-L17 PolarHBondContact O-N 2.86Å; L14-V18 WeakPolarHBondContact O-CB 3.45Å; L14-V18 VanDerWaalsContact O-CG2 3.3Å; L14-V18 WeakPolarHBondContact O-CG2 3.28Å; L14-V18 PolarHBondContact O-N 3.48Å
15	C	94.9	Very high	93.7	Very high	51 Å²	51	47 Å²	47	35%	0.345	27%	0.265	S	S	.	.	H	α-helix	trans	-57.7	-44.7	175.9	-73.1	0	0	0	0	112.1	F11 L12 V18 A19	F11-C15 WeakPolarHBondContact CZ-SG 3.34Å; F11-C15 PolarHBondContact O-N 2.97Å; F11-C15 PolarHBondContact O-SG 3.23Å; L12-C15 PolarHBondContact O-N 3.21Å; C15-V18 PolarHBondContact O-N 3.43Å; C15-A19 WeakPolarHBondContact O-CB 3.42Å; C15-A19 PolarHBondContact O-N 3.37Å
16	F	94.7	Very high	93.1	Very high	45 Å²	45	47.6 Å²	47.6	20%	0.197	27%	0.269	C	S	.	.	H	α-helix	trans	-72.2	-34.2	178.7	-84.7	-86.7	0	0	0	112.9	L12 A13 L14 A19 F20 F165 Y278 F281 N282 L285	L12-F16 WeakPolarHBondContact O-CD2 3.4Å; L12-F16 PolarHBondContact O-N 2.89Å; L12-F16 VanDerWaalsContact O-N 3.09Å; A13-F16 PolarHBondContact O-N 3.2Å; L14-F16 VanDerWaalsContact C-N 3.33Å; L14-F16 PolarHBondContact O-N 3.46Å; F16-A19 PolarHBondContact O-N 2.93Å; F16-F20 WeakPolarHBondContact O-CB 3.46Å; F16-F20 PolarHBondContact O-N 2.91Å; F16-F165 HydrophobicContact CE2-CZ 4.5Å; F16-Y278 HydrophobicContact CD2-CD2 4.06Å; F16-Y278 AromaticContact CD2-CE2 3.62Å; F16-Y278 HydrophobicContact CD2-CE2 3.62Å; F16-Y278 HydrophobicContact CE2-CD2 4.45Å; F16-Y278 AromaticContact CE2-CE2 3.58Å; F16-Y278 HydrophobicContact CE2-CE2 3.58Å; F16-Y278 HydrophobicContact CG-CE2 4.5Å; F16-Y278 HydrophobicContact CZ-CE2 4.42Å; F16-F281 HydrophobicContact CB-CB 3.83Å; F16-N282 HydrophobicContact CD1-CB 3.92Å; F16-N282 HydrophobicContact CE1-CB 4.11Å; F16-N282 WeakPolarHBondContact CE1-OD1 3.35Å; F16-N282 HydrophobicContact CG-CB 4.19Å; F16-L285 HydrophobicContact CD1-CD2 3.85Å; F16-L285 HydrophobicContact CE1-CD2 4.22Å
17	L	95.5	Very high	92.1	Very high	56 Å²	56	49.8 Å²	49.8	29%	0.293	29%	0.289	S	S	.	.	H	α-helix	trans	-63.5	-45.6	172.1	175.3	59.1	0	0	0	111.8	A13 L14 A19 F20 S21 F281	A13-L17 WeakPolarHBondContact O-CB 3.46Å; A13-L17 PolarHBondContact O-N 3.36Å; L14-L17 PolarHBondContact O-N 2.86Å; L17-A19 VanDerWaalsContact C-N 3.34Å; L17-F20 PolarHBondContact O-N 3.37Å; L17-S21 WeakPolarHBondContact O-CB 3.1Å; L17-S21 PolarHBondContact O-N 3.42Å; L17-S21 PolarHBondContact O-OG 3.22Å; L17-F281 HydrophobicContact CB-CD1 4.26Å; L17-F281 HydrophobicContact CB-CD2 3.76Å; L17-F281 HydrophobicContact CB-CE1 4.42Å; L17-F281 HydrophobicContact CB-CE2 3.88Å; L17-F281 HydrophobicContact CB-CG 3.95Å; L17-F281 HydrophobicContact CB-CZ 4.23Å; L17-F281 HydrophobicContact CD1-CD1 3.97Å; L17-F281 HydrophobicContact CD1-CE1 3.68Å; L17-F281 HydrophobicContact CD1-CE2 4.45Å; L17-F281 HydrophobicContact CD1-CZ 3.93Å; L17-F281 HydrophobicContact CD2-CE2 4.03Å; L17-F281 HydrophobicContact CD2-CZ 3.92Å; L17-F281 HydrophobicContact CG-CE1 4.42Å; L17-F281 HydrophobicContact CG-CE2 4.34Å; L17-F281 HydrophobicContact CG-CZ 4.24Å
18	V	94.2	Very high	91.1	Very high	89 Å²	89	55.3 Å²	55.3	54%	0.539	31%	0.309	S	S	.	.	H	α-helix	trans	-61.2	-46.7	174.9	170.7	0	0	0	0	109.2	L14 C15 F20 S21 V22	L14-V18 WeakPolarHBondContact O-CB 3.45Å; L14-V18 VanDerWaalsContact O-CG2 3.3Å; L14-V18 WeakPolarHBondContact O-CG2 3.28Å; L14-V18 PolarHBondContact O-N 3.48Å; C15-V18 PolarHBondContact O-N 3.43Å; V18-F20 VanDerWaalsContact C-N 3.34Å; V18-F20 PolarHBondContact O-N 3.49Å; V18-S21 PolarHBondContact O-N 3.12Å; V18-V22 HydrophobicContact CG1-CG2 4.07Å; V18-V22 WeakPolarHBondContact O-CB 3.33Å; V18-V22 VanDerWaalsContact O-CG2 3.24Å; V18-V22 WeakPolarHBondContact O-CG2 3.27Å; V18-V22 PolarHBondContact O-N 2.85Å
19	A	91.7	Very high	90	Very high	10 Å²	10	56.8 Å²	56.8	8%	0.083	31%	0.313	C	S	.	.	H	α-helix	trans	-60	-42.4	178.3	0	0	0	0	0	112.6	C15 F16 L17 H23 F42 I46 L285	C15-A19 WeakPolarHBondContact O-CB 3.42Å; C15-A19 PolarHBondContact O-N 3.37Å; F16-A19 PolarHBondContact O-N 2.93Å; L17-A19 VanDerWaalsContact C-N 3.34Å; A19-H23 WeakPolarHBondContact O-CB 3.15Å; A19-H23 PolarHBondContact O-N 3.25Å; A19-F42 HydrophobicContact CB-CE2 3.9Å; A19-F42 HydrophobicContact CB-CZ 3.87Å; A19-I46 HydrophobicContact CB-CG2 4.33Å; A19-L285 HydrophobicContact CB-CD2 3.8Å
20	F	91.2	Very high	88.5	Confident	25 Å²	25	60.4 Å²	60.4	11%	0.11	34%	0.337	C	S	.	.	H	α-helix	trans	-60.8	-46.8	173.3	177.3	-103.6	0	0	0	112.5	F16 L17 V18 H23 K24 A284 L285 Q288 L313	F16-F20 WeakPolarHBondContact O-CB 3.46Å; F16-F20 PolarHBondContact O-N 2.91Å; L17-F20 PolarHBondContact O-N 3.37Å; V18-F20 VanDerWaalsContact C-N 3.34Å; V18-F20 PolarHBondContact O-N 3.49Å; F20-H23 PolarHBondContact O-N 3.4Å; F20-K24 HydrophobicContact CD1-CD 4.43Å; F20-K24 HydrophobicContact CE1-CD 3.67Å; F20-K24 HydrophobicContact CE1-CG 4.4Å; F20-K24 HydrophobicContact CE2-CD 4.17Å; F20-K24 HydrophobicContact CE2-CG 4.4Å; F20-K24 HydrophobicContact CZ-CD 3.52Å; F20-K24 HydrophobicContact CZ-CG 4.21Å; F20-K24 PolarHBondContact O-N 2.92Å; F20-A284 HydrophobicContact CD2-CB 4.25Å; F20-A284 HydrophobicContact CE2-CB 4.19Å; F20-L285 HydrophobicContact CB-CB 4.38Å; F20-L285 HydrophobicContact CB-CD1 4.49Å; F20-L285 HydrophobicContact CD2-CB 4.45Å; F20-Q288 HydrophobicContact CD2-CB 4.47Å; F20-Q288 HydrophobicContact CE2-CB 3.92Å; F20-Q288 HydrophobicContact CE2-CG 4.23Å; F20-L313 HydrophobicContact CE2-CD2 4.19Å; F20-L313 HydrophobicContact CZ-CD1 3.93Å; F20-L313 HydrophobicContact CZ-CD2 3.77Å
21	S	90.9	Very high	86.7	Confident	60 Å²	60	67.8 Å²	67.8	42%	0.42	36%	0.361	S	S	.	.	H	α-helix	trans	-64.8	-44.5	-179.7	-55.6	0	0	0	0	111.5	L17 V18 H23 K24 A25	L17-S21 WeakPolarHBondContact O-CB 3.1Å; L17-S21 PolarHBondContact O-N 3.42Å; L17-S21 PolarHBondContact O-OG 3.22Å; V18-S21 PolarHBondContact O-N 3.12Å; S21-H23 PolarHBondContact O-N 3.27Å; S21-K24 PolarHBondContact O-N 3.41Å; S21-A25 WeakPolarHBondContact O-CB 3.48Å; S21-A25 PolarHBondContact O-N 3.47Å
22	V	89.3	Confident	84.8	Confident	61 Å²	61	69.1 Å²	69.1	37%	0.37	37%	0.369	S	S	.	.	H	α-helix	trans	-61.3	-43.4	174.9	171.4	0	0	0	0	110.7	V18 A25 S26 F42	V18-V22 HydrophobicContact CG1-CG2 4.07Å; V18-V22 WeakPolarHBondContact O-CB 3.33Å; V18-V22 VanDerWaalsContact O-CG2 3.24Å; V18-V22 WeakPolarHBondContact O-CG2 3.27Å; V18-V22 PolarHBondContact O-N 2.85Å; V22-A25 PolarHBondContact O-N 3.38Å; V22-S26 VanDerWaalsContact O-CB 3.25Å; V22-S26 WeakPolarHBondContact O-CB 3.16Å; V22-S26 PolarHBondContact O-N 3.04Å; V22-S26 PolarHBondContact O-OG 2.97Å; V22-F42 HydrophobicContact CB-CE1 4.23Å; V22-F42 HydrophobicContact CB-CZ 4.05Å; V22-F42 HydrophobicContact CG1-CD1 4.23Å; V22-F42 HydrophobicContact CG1-CE1 3.63Å; V22-F42 HydrophobicContact CG1-CZ 3.88Å
23	H	87.8	Confident	82.9	Confident	6 Å²	6	75.2 Å²	75.2	3%	0.028	39%	0.391	C	S	.	.	H	α-helix	trans	-60.6	-48.9	176.4	178	65	0	0	0	111.4	A19 F20 S21 A25 S26 A27 Q43 I46 L285 L289 D292	A19-H23 WeakPolarHBondContact O-CB 3.15Å; A19-H23 PolarHBondContact O-N 3.25Å; F20-H23 PolarHBondContact O-N 3.4Å; S21-H23 PolarHBondContact O-N 3.27Å; H23-A25 PolarHBondContact O-N 3.17Å; H23-S26 PolarHBondContact O-N 3.44Å; H23-S26 PolarHBondContact O-OG 3.43Å; H23-A27 PolarHBondContact O-N 3.22Å; H23-A27 VanDerWaalsContact O-N 3.07Å; H23-Q43 PolarHBondContact ND1-NE2 2.97Å; H23-I46 HydrophobicContact CB-CD1 4.5Å; H23-L285 HydrophobicContact CB-CD1 4.15Å; H23-L289 WeakPolarHBondContact CE1-CD2 3.48Å; H23-D292 IonicContact CD2-OD2 3.41Å; H23-D292 IonicContact CE1-OD2 3.81Å; H23-D292 IonicContact NE2-OD2 3.43Å; H23-D292 PolarHBondContact NE2-OD2 3.19Å
24	K	86.6	Confident	81.1	Confident	98 Å²	98	81 Å²	81	43%	0.426	41%	0.412	S	S	.	.	H	α-helix	trans	-61.5	-43.3	177	-75.5	-164.4	68.7	174.1	0	112.9	F20 S21 S26 A27	F20-K24 HydrophobicContact CD1-CD 4.43Å; F20-K24 HydrophobicContact CE1-CD 3.67Å; F20-K24 HydrophobicContact CE1-CG 4.4Å; F20-K24 HydrophobicContact CE2-CD 4.17Å; F20-K24 HydrophobicContact CE2-CG 4.4Å; F20-K24 HydrophobicContact CZ-CD 3.52Å; F20-K24 HydrophobicContact CZ-CG 4.21Å; F20-K24 PolarHBondContact O-N 2.92Å; S21-K24 PolarHBondContact O-N 3.41Å; K24-S26 VanDerWaalsContact C-N 3.33Å; K24-S26 PolarHBondContact O-N 2.98Å; K24-A27 WeakPolarHBondContact O-CB 3.11Å; K24-A27 PolarHBondContact O-N 3.43Å
25	A	86.4	Confident	79.3	Confident	51 Å²	51	85.4 Å²	85.4	42%	0.421	43%	0.428	S	S	.	.	H	α-helix	trans	-63.7	-39.9	175.7	0	0	0	0	0	111.4	S21 V22 H23 A27 Q28 L29	S21-A25 WeakPolarHBondContact O-CB 3.48Å; S21-A25 PolarHBondContact O-N 3.47Å; V22-A25 PolarHBondContact O-N 3.38Å; H23-A25 PolarHBondContact O-N 3.17Å; A25-A27 VanDerWaalsContact C-N 3.27Å; A25-A27 PolarHBondContact O-N 2.9Å; A25-Q28 WeakPolarHBondContact O-CB 3.32Å; A25-Q28 PolarHBondContact O-N 3.26Å; A25-L29 PolarHBondContact O-N 2.56Å
26	S	80.7	Confident	78.1	Confident	13 Å²	13	85.7 Å²	85.7	9%	0.091	43%	0.43	C	S	.	.	H	α-helix	trans	-66.7	-26.9	178.7	77.8	0	0	0	0	114	V22 H23 K24 Q28 L29	V22-S26 VanDerWaalsContact O-CB 3.25Å; V22-S26 WeakPolarHBondContact O-CB 3.16Å; V22-S26 PolarHBondContact O-N 3.04Å; V22-S26 PolarHBondContact O-OG 2.97Å; H23-S26 PolarHBondContact O-N 3.44Å; H23-S26 PolarHBondContact O-OG 3.43Å; K24-S26 VanDerWaalsContact C-N 3.33Å; K24-S26 PolarHBondContact O-N 2.98Å; S26-Q28 PolarHBondContact O-N 2.77Å; S26-L29 PolarHBondContact O-N 3.2Å
27	A	74.9	Confident	77	Confident	59 Å²	59	88 Å²	88	49%	0.488	45%	0.453	S	S	.	.	H	α-helix	trans	-66.7	-27.6	173.2	0	0	0	0	0	112.1	H23 K24 A25	H23-A27 PolarHBondContact O-N 3.22Å; H23-A27 VanDerWaalsContact O-N 3.07Å; K24-A27 WeakPolarHBondContact O-CB 3.11Å; K24-A27 PolarHBondContact O-N 3.43Å; A25-A27 VanDerWaalsContact C-N 3.27Å; A25-A27 PolarHBondContact O-N 2.9Å
28	Q	76.2	Confident	75.9	Confident	166 Å²	166	91.8 Å²	91.8	78%	0.776	47%	0.472	S	S	*	.	H	α-helix	trans	-88	-15	179.4	-61.9	176.9	-15.3	0	0	113.4	A25 S26	A25-Q28 WeakPolarHBondContact O-CB 3.32Å; A25-Q28 PolarHBondContact O-N 3.26Å; S26-Q28 PolarHBondContact O-N 2.77Å
29	L	71.6	Confident	74.9	Confident	84 Å²	84	89 Å²	89	44%	0.44	45%	0.454	S	S	.	.	S	Bend	trans	-73.6	144.4	-179.1	-81	166.8	0	0	0	112.8	A25 S26	A25-L29 PolarHBondContact O-N 2.56Å; S26-L29 PolarHBondContact O-N 3.2Å
30	P	65.7	Low	73.9	Confident	79 Å²	79	90.6 Å²	90.6	51%	0.513	46%	0.463	S	S	.	.			trans	-54.8	149.6	172	-23.3	32.5	0	0	0	112.6	E32 Y33	P30-E32 PolarHBondContact O-N 3.02Å; P30-Y33 PolarHBondContact O-N 3.43Å
31	R	59.4	Low	73.1	Confident	209 Å²	209	93 Å²	93	79%	0.789	48%	0.476	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.4	-24	-174.3	-80	-175.2	173.2	-177	-1.6	114.4	R34	R31-R34 WeakPolarHBondContact O-CB 3.48Å; R31-R34 PolarHBondContact O-N 2.84Å
32	E	58.6	Low	72.5	Confident	165 Å²	165	92.5 Å²	92.5	77%	0.771	47%	0.467	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.1	-42.3	-177.6	-64.8	-179.1	173.7	0	0	112.8	P30 R34	P30-E32 PolarHBondContact O-N 3.02Å; E32-R34 VanDerWaalsContact C-N 3.25Å; E32-R34 PolarHBondContact O-N 2.8Å
33	Y	56.6	Low	71.9	Confident	164 Å²	164	90.2 Å²	90.2	64%	0.643	45%	0.452	S	S	*	.	G	3₁₀ helix	trans	-74.6	-15.2	177.5	-71	-84	0	0	0	113.3	P30 K35	P30-Y33 PolarHBondContact O-N 3.43Å; Y33-K35 PolarHBondContact O-N 3.23Å
34	R	58.7	Low	71.3	Confident	122 Å²	122	90 Å²	90	46%	0.46	45%	0.451	S	S	.	.	G	3₁₀ helix	trans	-70.1	-15	-180	-161.6	175.2	-64.2	-175.3	-0.1	113.3	R31 E32 L39	R31-R34 WeakPolarHBondContact O-CB 3.48Å; R31-R34 PolarHBondContact O-N 2.84Å; E32-R34 VanDerWaalsContact C-N 3.25Å; E32-R34 PolarHBondContact O-N 2.8Å; R34-L39 HydrophobicContact CB-CD2 4.44Å; R34-L39 HydrophobicContact CG-CD2 4.09Å
35	K	59.4	Low	70.8	Confident	180 Å²	180	89.6 Å²	89.6	78%	0.783	45%	0.453	S	S	*	.	G	3₁₀ helix	trans	-89.8	2.1	-176.6	-67.8	-173.9	179.7	179.5	0	114.8	Y33 S37	Y33-K35 PolarHBondContact O-N 3.23Å; K35-S37 PolarHBondContact O-N 2.86Å
36	S	70.7	Confident	70.4	Confident	57 Å²	57	88.1 Å²	88.1	40%	0.399	44%	0.438	S	S	.	.			trans	-59.5	134.7	177.8	174	0	0	0	0	111.7	L38 L39 T40	S36-L38 PolarHBondContact O-N 2.9Å; S36-L38 PolarHBondContact OG-N 3.3Å; S36-L39 PolarHBondContact O-N 2.89Å; S36-L39 VanDerWaalsContact O-N 3.12Å; S36-T40 PolarHBondContact O-N 3.4Å; S36-T40 PolarHBondContact O-OG1 2.94Å; S36-T40 VanDerWaalsContact O-OG1 3.11Å
37	S	70.6	Confident	70.3	Confident	95 Å²	95	89.5 Å²	89.5	66%	0.664	44%	0.441	S	S	*	.	H	α-helix	trans	-57.2	-36	175.8	-63.1	0	0	0	0	112.1	K35 T40 L41	K35-S37 PolarHBondContact O-N 2.86Å; S37-T40 PolarHBondContact O-N 3.29Å; S37-L41 WeakPolarHBondContact O-CG 3.31Å; S37-L41 PolarHBondContact O-N 3.4Å
38	L	72.6	Confident	70	Confident	135 Å²	135	89.5 Å²	89.5	71%	0.707	43%	0.429	S	S	*	.	H	α-helix	trans	-65.6	-41.9	176.6	-68.1	174.2	0	0	0	112	S36 T40 L41 F42	S36-L38 PolarHBondContact O-N 2.9Å; S36-L38 PolarHBondContact OG-N 3.3Å; L38-T40 VanDerWaalsContact C-N 3.29Å; L38-T40 PolarHBondContact O-N 2.92Å; L38-L41 PolarHBondContact O-N 3.18Å; L38-F42 WeakPolarHBondContact O-CB 3.42Å; L38-F42 PolarHBondContact O-N 3.28Å
39	L	73	Confident	69.9	Low	31 Å²	31	81.7 Å²	81.7	16%	0.162	39%	0.393	C	S	.	.	H	α-helix	trans	-66.9	-34.8	176.2	-172.4	68.5	0	0	0	111	R34 S36 F42 Q43	R34-L39 HydrophobicContact CB-CD2 4.44Å; R34-L39 HydrophobicContact CG-CD2 4.09Å; S36-L39 PolarHBondContact O-N 2.89Å; S36-L39 VanDerWaalsContact O-N 3.12Å; L39-F42 HydrophobicContact CD1-CD1 4.17Å; L39-F42 PolarHBondContact O-N 3.5Å; L39-Q43 HydrophobicContact CD1-CG 4.42Å; L39-Q43 HydrophobicContact CG-CG 4.26Å; L39-Q43 VanDerWaalsContact O-CB 3.28Å; L39-Q43 WeakPolarHBondContact O-CB 3.45Å; L39-Q43 WeakPolarHBondContact O-CG 3.36Å; L39-Q43 PolarHBondContact O-N 2.91Å
40	T	71.9	Confident	69.4	Low	42 Å²	42	79.8 Å²	79.8	26%	0.258	38%	0.381	S	S	.	.	H	α-helix	trans	-67	-43.5	176.7	-54.1	0	0	0	0	111.6	S36 S37 L38 Q43 D44	S36-T40 PolarHBondContact O-N 3.4Å; S36-T40 PolarHBondContact O-OG1 2.94Å; S36-T40 VanDerWaalsContact O-OG1 3.11Å; S37-T40 PolarHBondContact O-N 3.29Å; L38-T40 VanDerWaalsContact C-N 3.29Å; L38-T40 PolarHBondContact O-N 2.92Å; T40-Q43 PolarHBondContact O-N 3.15Å; T40-D44 WeakPolarHBondContact O-CB 3.47Å; T40-D44 PolarHBondContact O-N 3.34Å
41	L	73.6	Confident	69.3	Low	76 Å²	76	76.5 Å²	76.5	40%	0.398	36%	0.359	S	S	.	.	H	α-helix	trans	-62.4	-44.8	173.7	-72.1	170.1	0	0	0	111.8	S37 L38 D44 L45 W60 L61	S37-L41 WeakPolarHBondContact O-CG 3.31Å; S37-L41 PolarHBondContact O-N 3.4Å; L38-L41 PolarHBondContact O-N 3.18Å; L41-D44 PolarHBondContact O-N 2.88Å; L41-L45 WeakPolarHBondContact O-CB 3.35Å; L41-L45 PolarHBondContact O-N 3.15Å; L41-W60 HydrophobicContact CD2-CH2 4.02Å; L41-W60 HydrophobicContact CD2-CZ2 4.29Å; L41-L61 HydrophobicContact CD2-CD1 4.32Å; L41-L61 HydrophobicContact CD2-CD2 3.79Å
42	F	79.1	Confident	69.7	Low	50 Å²	50	66.6 Å²	66.6	22%	0.219	32%	0.322	C	S	.	.	H	α-helix	trans	-60.1	-46.5	175.1	172.8	-103.9	0	0	0	111.8	A19 V22 L38 L39 D44 L45 I46	A19-F42 HydrophobicContact CB-CE2 3.9Å; A19-F42 HydrophobicContact CB-CZ 3.87Å; V22-F42 HydrophobicContact CB-CE1 4.23Å; V22-F42 HydrophobicContact CB-CZ 4.05Å; V22-F42 HydrophobicContact CG1-CD1 4.23Å; V22-F42 HydrophobicContact CG1-CE1 3.63Å; V22-F42 HydrophobicContact CG1-CZ 3.88Å; L38-F42 WeakPolarHBondContact O-CB 3.42Å; L38-F42 PolarHBondContact O-N 3.28Å; L39-F42 HydrophobicContact CD1-CD1 4.17Å; L39-F42 PolarHBondContact O-N 3.5Å; F42-D44 VanDerWaalsContact C-N 3.32Å; F42-D44 PolarHBondContact O-N 2.89Å; F42-L45 PolarHBondContact O-N 2.9Å; F42-I46 HydrophobicContact CD1-CD1 4.15Å; F42-I46 HydrophobicContact CD2-CG2 4.24Å; F42-I46 HydrophobicContact CE1-CD1 3.64Å; F42-I46 HydrophobicContact CE1-CG2 4.46Å; F42-I46 HydrophobicContact CE2-CG2 3.8Å; F42-I46 HydrophobicContact CZ-CD1 3.98Å; F42-I46 HydrophobicContact CZ-CG2 3.91Å; F42-I46 WeakPolarHBondContact O-CG1 3.24Å; F42-I46 WeakPolarHBondContact O-CG2 3.44Å; F42-I46 PolarHBondContact O-N 3.46Å; F42-I46 VanDerWaalsContact O-N 3.07Å
43	Q	76.6	Confident	69.7	Low	13 Å²	13	64.3 Å²	64.3	6%	0.061	31%	0.311	C	S	.	.	H	α-helix	trans	-65.6	-33.3	177.9	-70	-74.9	-29.8	0	0	112	H23 L39 T40 R47 L55	H23-Q43 PolarHBondContact ND1-NE2 2.97Å; L39-Q43 HydrophobicContact CD1-CG 4.42Å; L39-Q43 HydrophobicContact CG-CG 4.26Å; L39-Q43 VanDerWaalsContact O-CB 3.28Å; L39-Q43 WeakPolarHBondContact O-CB 3.45Å; L39-Q43 WeakPolarHBondContact O-CG 3.36Å; L39-Q43 PolarHBondContact O-N 2.91Å; T40-Q43 PolarHBondContact O-N 3.15Å; Q43-R47 VanDerWaalsContact O-CB 3.27Å; Q43-R47 WeakPolarHBondContact O-CB 3.25Å; Q43-R47 WeakPolarHBondContact O-CD 3.25Å; Q43-R47 WeakPolarHBondContact O-CG 3.46Å; Q43-R47 PolarHBondContact O-N 2.89Å; Q43-R47 VanDerWaalsContact OE1-CZ 3.29Å; Q43-L55 HydrophobicContact CB-CD1 4.22Å; Q43-L55 HydrophobicContact CB-CD2 4.21Å
44	D	74.2	Confident	69.8	Low	2 Å²	2	60.6 Å²	60.6	1%	0.011	31%	0.306	C	S	.	.	H	α-helix	trans	-66	-39.8	172.3	-164.5	78.9	0	0	0	112.1	T40 L41 F42 K52 R57 H159	T40-D44 WeakPolarHBondContact O-CB 3.47Å; T40-D44 PolarHBondContact O-N 3.34Å; L41-D44 PolarHBondContact O-N 2.88Å; F42-D44 VanDerWaalsContact C-N 3.32Å; F42-D44 PolarHBondContact O-N 2.89Å; D44-K52 VanDerWaalsContact O-CE 3.3Å; D44-K52 WeakPolarHBondContact O-CE 3.19Å; D44-K52 WeakPolarHBondContact OD1-CE 3.43Å; D44-K52 IonicContact OD1-NZ 3.74Å; D44-K52 PolarHBondContact OD1-NZ 2.94Å; D44-K52 VanDerWaalsContact OD2-CE 3.29Å; D44-K52 WeakPolarHBondContact OD2-CE 3.47Å; D44-K52 IonicContact OD2-NZ 2.81Å; D44-K52 PolarHBondContact OD2-NZ 2.93Å; D44-R57 WeakPolarHBondContact OD1-CD 3.1Å; D44-R57 IonicContact OD1-CZ 3.34Å; D44-R57 IonicContact OD1-NE 3.12Å; D44-R57 PolarHBondContact OD1-NE 3.46Å; D44-R57 IonicContact OD1-NH1 3.15Å; D44-R57 PolarHBondContact OD1-NH1 3.38Å; D44-H159 IonicContact OD2-CD2 3.4Å; D44-H159 PolarHBondContact OD2-CD2 3.04Å
45	L	76.4	Confident	69.8	Low	88 Å²	88	56.7 Å²	56.7	46%	0.461	29%	0.294	S	S	.	.	H	α-helix	trans	-73	-28.9	-178.5	-172.3	66.3	0	0	0	113.6	L41 F42 V161 Q162	L41-L45 WeakPolarHBondContact O-CB 3.35Å; L41-L45 PolarHBondContact O-N 3.15Å; F42-L45 PolarHBondContact O-N 2.9Å; L45-V161 HydrophobicContact CD1-CB 4.36Å; L45-V161 HydrophobicContact CD1-CG1 4.3Å; L45-Q162 PolarHBondContact O-NE2 3.4Å
46	I	78.7	Confident	69.7	Low	20 Å²	20	57.3 Å²	57.3	10%	0.103	30%	0.299	C	S	.	.	H	α-helix	trans	-92.5	-25.2	-179.9	68.7	-177.3	0	0	0	113.2	A19 H23 F42 L285 L289	A19-I46 HydrophobicContact CB-CG2 4.33Å; H23-I46 HydrophobicContact CB-CD1 4.5Å; F42-I46 HydrophobicContact CD1-CD1 4.15Å; F42-I46 HydrophobicContact CD2-CG2 4.24Å; F42-I46 HydrophobicContact CE1-CD1 3.64Å; F42-I46 HydrophobicContact CE1-CG2 4.46Å; F42-I46 HydrophobicContact CE2-CG2 3.8Å; F42-I46 HydrophobicContact CZ-CD1 3.98Å; F42-I46 HydrophobicContact CZ-CG2 3.91Å; F42-I46 WeakPolarHBondContact O-CG1 3.24Å; F42-I46 WeakPolarHBondContact O-CG2 3.44Å; F42-I46 PolarHBondContact O-N 3.46Å; F42-I46 VanDerWaalsContact O-N 3.07Å; I46-L285 HydrophobicContact CB-CD2 4.13Å; I46-L285 HydrophobicContact CD1-CD1 4.41Å; I46-L285 HydrophobicContact CG2-CD2 4.13Å; I46-L289 HydrophobicContact CB-CD1 4.35Å; I46-L289 HydrophobicContact CD1-CD1 4.28Å; I46-L289 HydrophobicContact CD1-CD2 4.34Å; I46-L289 HydrophobicContact CG1-CD1 4.03Å
47	R	78.2	Confident	69.3	Low	43 Å²	43	56 Å²	56	16%	0.162	29%	0.285	C	S	.	.			trans	-91.3	147.6	-178	-71	166.3	-179.2	-122.6	6.3	111.1	Q43 T51 K52 Q162 L289	Q43-R47 VanDerWaalsContact O-CB 3.27Å; Q43-R47 WeakPolarHBondContact O-CB 3.25Å; Q43-R47 WeakPolarHBondContact O-CD 3.25Å; Q43-R47 WeakPolarHBondContact O-CG 3.46Å; Q43-R47 PolarHBondContact O-N 2.89Å; Q43-R47 VanDerWaalsContact OE1-CZ 3.29Å; R47-T51 WeakPolarHBondContact CD-O 3.43Å; R47-T51 PolarHBondContact NH1-O 2.91Å; R47-K52 HydrophobicContact CB-CB 4.35Å; R47-K52 HydrophobicContact CB-CG 4.26Å; R47-Q162 PolarHBondContact O-NE2 3.47Å; R47-Q162 VanDerWaalsContact O-NE2 3.14Å; R47-L289 HydrophobicContact CG-CD1 4.1Å; R47-L289 HydrophobicContact CG-CD2 3.97Å
48	Y	69.2	Low	69.1	Low	59 Å²	59	53.9 Å²	53.9	23%	0.231	27%	0.274	C	S	.	.			trans	-149.9	152.9	174.6	65.6	-90.8	0	0	0	111.5	K50 T51 Y251 A286	Y48-K50 PolarHBondContact O-N 3.07Å; Y48-T51 PolarHBondContact N-OG1 3.36Å; Y48-T51 PolarHBondContact O-N 3.3Å; Y48-T51 PolarHBondContact O-OG1 3.44Å; Y48-Y251 PolarHBondContact OH-OH 3.33Å; Y48-Y251 VanDerWaalsContact OH-OH 3.04Å; Y48-A286 HydrophobicContact CE1-CB 4.38Å
49	G	73.1	Confident	68.7	Low	1 Å²	1	55 Å²	55	1%	0.01	28%	0.276	C	S	.	.	G	3₁₀ helix	trans	58	-121	-177.6	0	0	0	0	0	112.4	T51 K52 Q53 A157	G49-T51 VanDerWaalsContact C-N 3.32Å; G49-T51 PolarHBondContact O-N 3.08Å; G49-K52 WeakPolarHBondContact O-CB 3.44Å; G49-K52 PolarHBondContact O-N 3.45Å; G49-K52 VanDerWaalsContact O-N 3.13Å; G49-Q53 PolarHBondContact O-N 3.26Å; G49-A157 PolarHBondContact N-O 2.85Å
50	K	61.9	Low	68.6	Low	45 Å²	45	60.7 Å²	60.7	20%	0.196	30%	0.295	C	S	.	.	G	3₁₀ helix	trans	-64.9	-32	-173.9	60.2	170.6	-174.9	173.5	0	113.8	Y48 K52 H235 C290 L293 Y294	Y48-K50 PolarHBondContact O-N 3.07Å; K50-K52 PolarHBondContact O-N 3.48Å; K50-H235 VanDerWaalsContact CD-CD2 3.48Å; K50-H235 WeakPolarHBondContact CD-CD2 3.28Å; K50-H235 WeakPolarHBondContact CD-NE2 3.32Å; K50-H235 PolarHBondContact NZ-CE1 3.34Å; K50-H235 PolarHBondContact NZ-NE2 2.88Å; K50-C290 WeakPolarHBondContact CE-SG 3.26Å; K50-C290 PolarHBondContact NZ-SG 2.93Å; K50-L293 HydrophobicContact CB-CD2 4Å; K50-L293 HydrophobicContact CD-CD2 3.76Å; K50-L293 HydrophobicContact CG-CD2 3.74Å; K50-Y294 VanDerWaalsContact NZ-CZ 3.29Å; K50-Y294 PolarHBondContact NZ-OH 3.33Å
51	T	62.8	Low	68.3	Low	10 Å²	10	59.3 Å²	59.3	6%	0.061	29%	0.286	C	S	.	.	G	3₁₀ helix	trans	-75.1	-19.5	178.9	57.4	0	0	0	0	111.7	R47 Y48 G49 T54 L289 L293	R47-T51 WeakPolarHBondContact CD-O 3.43Å; R47-T51 PolarHBondContact NH1-O 2.91Å; Y48-T51 PolarHBondContact N-OG1 3.36Å; Y48-T51 PolarHBondContact O-N 3.3Å; Y48-T51 PolarHBondContact O-OG1 3.44Å; G49-T51 VanDerWaalsContact C-N 3.32Å; G49-T51 PolarHBondContact O-N 3.08Å; T51-T54 PolarHBondContact O-OG1 3.23Å; T51-T54 VanDerWaalsContact O-OG1 3.14Å; T51-L289 HydrophobicContact CG2-CB 4.18Å; T51-L293 HydrophobicContact CG2-CB 4.38Å; T51-L293 HydrophobicContact CG2-CD2 3.95Å
52	K	67.8	Low	68.2	Low	1 Å²	1	62.3 Å²	62.3	0%	0.004	29%	0.292	C	S	.	.	T	Hydrogen-bonded Turn	trans	-83.3	-27.6	178.7	-140.2	-173.1	-171.8	-165.4	0	113.1	D44 R47 G49 K50 T54 L55 R57 D65	D44-K52 VanDerWaalsContact O-CE 3.3Å; D44-K52 WeakPolarHBondContact O-CE 3.19Å; D44-K52 WeakPolarHBondContact OD1-CE 3.43Å; D44-K52 IonicContact OD1-NZ 3.74Å; D44-K52 PolarHBondContact OD1-NZ 2.94Å; D44-K52 VanDerWaalsContact OD2-CE 3.29Å; D44-K52 WeakPolarHBondContact OD2-CE 3.47Å; D44-K52 IonicContact OD2-NZ 2.81Å; D44-K52 PolarHBondContact OD2-NZ 2.93Å; R47-K52 HydrophobicContact CB-CB 4.35Å; R47-K52 HydrophobicContact CB-CG 4.26Å; G49-K52 WeakPolarHBondContact O-CB 3.44Å; G49-K52 PolarHBondContact O-N 3.45Å; G49-K52 VanDerWaalsContact O-N 3.13Å; K50-K52 PolarHBondContact O-N 3.48Å; K52-T54 VanDerWaalsContact C-N 3.27Å; K52-T54 PolarHBondContact O-N 2.78Å; K52-L55 PolarHBondContact O-N 3.41Å; K52-R57 PolarHBondContact O-NH2 2.86Å; K52-D65 IonicContact NZ-OD1 3.41Å; K52-D65 PolarHBondContact NZ-OD1 2.91Å
53	Q	58.3	Low	68	Low	116 Å²	116	65.4 Å²	65.4	54%	0.542	32%	0.315	S	S	.	.	T	Hydrogen-bonded Turn	trans	-68.3	-23.2	-177.5	-73.4	178.2	-17.9	0	0	113.4	G49 L55 D155	G49-Q53 PolarHBondContact O-N 3.26Å; Q53-L55 VanDerWaalsContact C-N 3.33Å; Q53-L55 PolarHBondContact O-N 3.17Å; Q53-D155 PolarHBondContact NE2-O 3.39Å
54	T	58.7	Low	68.2	Low	87 Å²	87	69.1 Å²	69.1	53%	0.534	33%	0.331	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.2	-2.4	179.6	48.1	0	0	0	0	114.4	T51 K52 L293	T51-T54 PolarHBondContact O-OG1 3.23Å; T51-T54 VanDerWaalsContact O-OG1 3.14Å; K52-T54 VanDerWaalsContact C-N 3.27Å; K52-T54 PolarHBondContact O-N 2.78Å; T54-L293 HydrophobicContact CG2-CD1 3.71Å
55	L	59.5	Low	68.6	Low	39 Å²	39	71 Å²	71	20%	0.204	34%	0.341	C	S	.	.	S	Bend	trans	-92.2	127.9	179.4	-75.2	167.7	0	0	0	111.1	Q43 K52 Q53 R57	Q43-L55 HydrophobicContact CB-CD1 4.22Å; Q43-L55 HydrophobicContact CB-CD2 4.21Å; K52-L55 PolarHBondContact O-N 3.41Å; Q53-L55 VanDerWaalsContact C-N 3.33Å; Q53-L55 PolarHBondContact O-N 3.17Å; L55-R57 HydrophobicContact CB-CG 3.81Å; L55-R57 PolarHBondContact O-N 2.82Å
56	H	57.2	Low	69	Low	193 Å²	193	67.4 Å²	67.4	89%	0.894	32%	0.322	S	S	*	.			trans	-75.6	112.5	168.8	-163.8	-83.1	0	0	0	109.1
57	R	62.9	Low	69.4	Low	29 Å²	29	68.7 Å²	68.7	11%	0.109	33%	0.332	C	S	.	.			trans	-129.7	142.5	-168.3	-66.4	-176.9	-82	146.6	2.5	112.3	D44 K52 L55 D65	D44-R57 WeakPolarHBondContact OD1-CD 3.1Å; D44-R57 IonicContact OD1-CZ 3.34Å; D44-R57 IonicContact OD1-NE 3.12Å; D44-R57 PolarHBondContact OD1-NE 3.46Å; D44-R57 IonicContact OD1-NH1 3.15Å; D44-R57 PolarHBondContact OD1-NH1 3.38Å; K52-R57 PolarHBondContact O-NH2 2.86Å; L55-R57 HydrophobicContact CB-CG 3.81Å; L55-R57 PolarHBondContact O-N 2.82Å; R57-D65 IonicContact NH1-OD1 2.93Å; R57-D65 IonicContact NH1-OD2 2.76Å; R57-D65 PolarHBondContact NH1-OD2 2.86Å
58	A	64.5	Low	69.6	Low	51 Å²	51	69 Å²	69	42%	0.421	34%	0.335	S	S	.	.			trans	-62.7	149	172.1	0	0	0	0	0	111.1	W60 L61	A58-W60 VanDerWaalsContact C-N 3.32Å; A58-W60 PolarHBondContact O-N 3.47Å; A58-L61 PolarHBondContact O-N 2.95Å
59	E	65.6	Low	70.4	Confident	160 Å²	160	72.5 Å²	72.5	75%	0.748	35%	0.347	S	S	*	.	H	α-helix	trans	-64	-33.8	-172.3	-66.2	-175.8	157.6	0	0	113.3	L61 R62	E59-L61 VanDerWaalsContact C-N 3.27Å; E59-L61 PolarHBondContact O-N 3.32Å; E59-R62 WeakPolarHBondContact O-CB 3.19Å; E59-R62 PolarHBondContact O-N 3.33Å
60	W	69.6	Low	71.1	Confident	150 Å²	150	77.4 Å²	77.4	57%	0.568	37%	0.366	S	S	*	.	H	α-helix	trans	-62.9	-30.6	-179.9	72.8	-94.4	0	0	0	113.5	L41 A58 R62 V63 F64	L41-W60 HydrophobicContact CD2-CH2 4.02Å; L41-W60 HydrophobicContact CD2-CZ2 4.29Å; A58-W60 VanDerWaalsContact C-N 3.32Å; A58-W60 PolarHBondContact O-N 3.47Å; W60-R62 PolarHBondContact O-N 2.86Å; W60-V63 WeakPolarHBondContact O-CB 3.39Å; W60-V63 WeakPolarHBondContact O-CG2 3.3Å; W60-V63 PolarHBondContact O-N 3.34Å; W60-F64 HydrophobicContact CE3-CE2 4.42Å
61	L	65.9	Low	72.4	Confident	12 Å²	12	77.4 Å²	77.4	6%	0.063	37%	0.366	C	S	.	.	H	α-helix	trans	-68.6	-23.3	175.9	-75.2	168.7	0	0	0	112.3	L41 A58 E59 V63	L41-L61 HydrophobicContact CD2-CD1 4.32Å; L41-L61 HydrophobicContact CD2-CD2 3.79Å; A58-L61 PolarHBondContact O-N 2.95Å; E59-L61 VanDerWaalsContact C-N 3.27Å; E59-L61 PolarHBondContact O-N 3.32Å; L61-V63 VanDerWaalsContact C-N 3.29Å
62	R	72	Confident	73.9	Confident	139 Å²	139	81.5 Å²	81.5	53%	0.525	38%	0.38	S	S	.	.	H	α-helix	trans	-77.5	-16	178.2	-55.8	-178.9	-173.6	177.6	3.7	112.5	E59 W60 F64 D65	E59-R62 WeakPolarHBondContact O-CB 3.19Å; E59-R62 PolarHBondContact O-N 3.33Å; W60-R62 PolarHBondContact O-N 2.86Å; R62-F64 PolarHBondContact O-N 3.01Å; R62-D65 WeakPolarHBondContact O-CB 3.34Å; R62-D65 PolarHBondContact O-N 2.9Å; R62-D65 VanDerWaalsContact O-N 3.14Å
63	V	75.9	Confident	75.2	Confident	115 Å²	115	83.3 Å²	83.3	70%	0.697	39%	0.389	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.8	-29.5	174.7	179.6	0	0	0	0	111	W60 L61	W60-V63 WeakPolarHBondContact O-CB 3.39Å; W60-V63 WeakPolarHBondContact O-CG2 3.3Å; W60-V63 PolarHBondContact O-N 3.34Å; L61-V63 VanDerWaalsContact C-N 3.29Å
64	F	79.9	Confident	77	Confident	91 Å²	91	78.4 Å²	78.4	40%	0.399	37%	0.365	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94	10.8	178.6	-58.4	-73.1	0	0	0	113.5	W60 R62 V66 H159 L160	W60-F64 HydrophobicContact CE3-CE2 4.42Å; R62-F64 PolarHBondContact O-N 3.01Å; F64-V66 PolarHBondContact O-N 2.79Å; F64-H159 CarbonylContact O-C 3.58Å; F64-L160 HydrophobicContact CB-CB 4.25Å; F64-L160 HydrophobicContact CD1-CD2 4.19Å; F64-L160 WeakPolarHBondContact O-CB 3.01Å; F64-L160 PolarHBondContact O-N 3.19Å
65	D	83.6	Confident	78.8	Confident	43 Å²	43	74.6 Å²	74.6	23%	0.23	34%	0.341	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-81.3	118.7	178.1	-86.8	-17.9	0	0	0	110.6	K52 R57 R62 A157	K52-D65 IonicContact NZ-OD1 3.41Å; K52-D65 PolarHBondContact NZ-OD1 2.91Å; R57-D65 IonicContact NH1-OD1 2.93Å; R57-D65 IonicContact NH1-OD2 2.76Å; R57-D65 PolarHBondContact NH1-OD2 2.86Å; R62-D65 WeakPolarHBondContact O-CB 3.34Å; R62-D65 PolarHBondContact O-N 2.9Å; R62-D65 VanDerWaalsContact O-N 3.14Å; D65-A157 HydrophobicContact CB-CB 3.64Å
66	V	84.4	Confident	80.6	Confident	11 Å²	11	73.8 Å²	73.8	7%	0.067	34%	0.34	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.4	135.7	173.9	-180	0	0	0	0	109.3	F64 K68 W70 A157 M158 L160 Y163	F64-V66 PolarHBondContact O-N 2.79Å; V66-K68 PolarHBondContact O-N 3.09Å; V66-W70 HydrophobicContact CG1-CD2 4.08Å; V66-W70 HydrophobicContact CG1-CE3 3.35Å; V66-W70 HydrophobicContact CG1-CZ3 3.89Å; V66-A157 CarbonylContact O-C 3.56Å; V66-A157 WeakPolarHBondContact O-CA 3.46Å; V66-M158 HydrophobicContact CB-CG 4Å; V66-M158 HydrophobicContact CG1-CG 4.47Å; V66-M158 PolarHBondContact N-O 3.4Å; V66-M158 PolarHBondContact O-N 3.48Å; V66-L160 HydrophobicContact CG2-CB 4.08Å; V66-L160 HydrophobicContact CG2-CD1 3.78Å; V66-Y163 HydrophobicContact CB-CG 4.48Å; V66-Y163 HydrophobicContact CG1-CD1 4.47Å; V66-Y163 HydrophobicContact CG1-CD2 3.93Å; V66-Y163 HydrophobicContact CG1-CE2 4.35Å; V66-Y163 HydrophobicContact CG1-CG 4.01Å; V66-Y163 HydrophobicContact CG2-CG 4.36Å
67	P	85.8	Confident	82.6	Confident	48 Å²	48	67.4 Å²	67.4	31%	0.312	31%	0.312	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-58.6	129.4	179.7	-25.9	35.1	0	0	0	112.7	R69 W70	P67-R69 HydrophobicContact CB-CG 3.67Å; P67-R69 PolarHBondContact O-N 3.29Å; P67-R69 VanDerWaalsContact O-N 3.09Å; P67-W70 WeakPolarHBondContact O-CB 3.29Å; P67-W70 PolarHBondContact O-N 3.37Å
68	K	82.3	Confident	84.2	Confident	49 Å²	49	66.1 Å²	66.1	21%	0.213	31%	0.308	C	S	.	.	G	3₁₀ helix	trans	-59.9	-26.1	178.2	-178.2	177.2	176.5	179.1	0	112.9	V66 W70 F71 F153 G156 M158	V66-K68 PolarHBondContact O-N 3.09Å; K68-W70 PolarHBondContact O-N 3.32Å; K68-W70 VanDerWaalsContact O-N 3.08Å; K68-F71 VanDerWaalsContact O-CB 3.3Å; K68-F71 WeakPolarHBondContact O-CB 3.39Å; K68-F71 PolarHBondContact O-N 2.96Å; K68-F153 HydrophobicContact CG-CD1 4.24Å; K68-G156 WeakPolarHBondContact CB-O 3.42Å; K68-G156 PolarHBondContact N-O 3.33Å; K68-M158 HydrophobicContact CG-CE 4.39Å
69	R	86.3	Confident	85.8	Confident	132 Å²	132	64.3 Å²	64.3	50%	0.498	29%	0.291	S	S	.	.	G	3₁₀ helix	trans	-57.8	-18.4	174.5	63.3	-176.6	79.4	-178	2.9	113.5	P67 F71 F153 D155	P67-R69 HydrophobicContact CB-CG 3.67Å; P67-R69 PolarHBondContact O-N 3.29Å; P67-R69 VanDerWaalsContact O-N 3.09Å; R69-F71 PolarHBondContact O-N 3.36Å; R69-F153 HydrophobicContact CB-CB 4.21Å; R69-D155 IonicContact CZ-OD1 3.81Å; R69-D155 IonicContact NH2-OD1 3.19Å; R69-D155 PolarHBondContact NH2-OD1 3.01Å
70	W	89.2	Confident	87.4	Confident	105 Å²	105	60.9 Å²	60.9	40%	0.398	28%	0.284	S	S	.	.	G	3₁₀ helix	trans	-79.7	5.7	175	-67.4	1.3	0	0	0	114	V66 P67 K68 W72 H73 Y163	V66-W70 HydrophobicContact CG1-CD2 4.08Å; V66-W70 HydrophobicContact CG1-CE3 3.35Å; V66-W70 HydrophobicContact CG1-CZ3 3.89Å; P67-W70 WeakPolarHBondContact O-CB 3.29Å; P67-W70 PolarHBondContact O-N 3.37Å; K68-W70 PolarHBondContact O-N 3.32Å; K68-W70 VanDerWaalsContact O-N 3.08Å; W70-W72 PolarHBondContact O-N 3.41Å; W70-W72 VanDerWaalsContact O-N 3.1Å; W70-H73 AromaticContact CD1-CE1 3.88Å; W70-H73 AromaticContact CD2-CE1 3.61Å; W70-H73 AromaticContact CE3-CE1 3.94Å; W70-H73 AromaticContact CG-CE1 3.46Å; W70-H73 VanDerWaalsContact CG-CE1 3.46Å; W70-H73 AromaticContact CG-ND1 3.88Å; W70-H73 VanDerWaalsContact O-CB 3.28Å; W70-H73 WeakPolarHBondContact O-CB 3.32Å; W70-H73 VanDerWaalsContact O-CG 3.3Å; W70-H73 PolarHBondContact O-N 3.42Å; W70-Y163 HydrophobicContact CB-CE2 4.19Å; W70-Y163 HydrophobicContact CE3-CE2 4.38Å
71	F	88.2	Confident	88.7	Confident	45 Å²	45	55.6 Å²	55.6	20%	0.197	26%	0.264	C	S	.	.	H	α-helix	trans	-57.5	-25.9	177.7	-158.6	-108.9	0	0	0	113.4	K68 R69 H73 F74 Y75 F153 M158	K68-F71 VanDerWaalsContact O-CB 3.3Å; K68-F71 WeakPolarHBondContact O-CB 3.39Å; K68-F71 PolarHBondContact O-N 2.96Å; R69-F71 PolarHBondContact O-N 3.36Å; F71-H73 PolarHBondContact O-N 3.37Å; F71-F74 AromaticContact CD2-CD2 3.62Å; F71-F74 HydrophobicContact CD2-CD2 3.62Å; F71-F74 AromaticContact CD2-CE2 3.46Å; F71-F74 HydrophobicContact CD2-CE2 3.46Å; F71-F74 VanDerWaalsContact CD2-CE2 3.46Å; F71-F74 AromaticContact CE2-CD2 3.79Å; F71-F74 HydrophobicContact CE2-CD2 3.79Å; F71-F74 AromaticContact CE2-CE2 3.72Å; F71-F74 HydrophobicContact CE2-CE2 3.72Å; F71-F74 HydrophobicContact CG-CD2 4.15Å; F71-F74 HydrophobicContact CG-CE2 4.32Å; F71-F74 HydrophobicContact CZ-CD2 4.46Å; F71-F74 WeakPolarHBondContact O-CD2 3.22Å; F71-F74 PolarHBondContact O-N 3.06Å; F71-Y75 HydrophobicContact CD1-CD2 4.47Å; F71-Y75 AromaticContact CD1-CE2 3.64Å; F71-Y75 HydrophobicContact CD1-CE2 3.64Å; F71-Y75 AromaticContact CE1-CE2 3.47Å; F71-Y75 HydrophobicContact CE1-CE2 3.47Å; F71-Y75 VanDerWaalsContact CE1-CE2 3.47Å; F71-Y75 AromaticContact CE1-CZ 3.83Å; F71-Y75 WeakPolarHBondContact CE1-OH 3.45Å; F71-Y75 HydrophobicContact CZ-CE2 4.43Å; F71-F153 HydrophobicContact CB-CE1 3.98Å; F71-F153 HydrophobicContact CB-CZ 4.19Å; F71-M158 HydrophobicContact CD2-CE 3.79Å
72	W	93.7	Very high	90.2	Very high	96 Å²	96	55.1 Å²	55.1	36%	0.364	26%	0.261	S	S	.	.	H	α-helix	trans	-66.1	-24.6	175.5	71.5	-98.6	0	0	0	113.1	W70 F74 Y75 A76 L144 C147 L148	W70-W72 PolarHBondContact O-N 3.41Å; W70-W72 VanDerWaalsContact O-N 3.1Å; W72-F74 VanDerWaalsContact C-N 3.26Å; W72-F74 PolarHBondContact O-N 2.88Å; W72-Y75 PolarHBondContact O-N 3.44Å; W72-A76 HydrophobicContact CE3-CB 3.9Å; W72-A76 HydrophobicContact CZ3-CB 3.89Å; W72-A76 PolarHBondContact O-N 2.88Å; W72-L144 HydrophobicContact CB-CD1 4.11Å; W72-L144 HydrophobicContact CE3-CD1 4.16Å; W72-C147 HydrophobicContact CB-CB 3.75Å; W72-L148 HydrophobicContact CB-CD2 4.23Å; W72-L148 HydrophobicContact CD2-CD2 4.26Å; W72-L148 HydrophobicContact CG-CD2 4.1Å
73	H	96.3	Very high	91.4	Very high	39 Å²	39	52 Å²	52	18%	0.181	26%	0.255	C	S	.	.	H	α-helix	trans	-58.4	-39.6	178.2	-63.6	169	0	0	0	111.7	W70 F71 Y75 A76 I77 Y163 L167	W70-H73 AromaticContact CD1-CE1 3.88Å; W70-H73 AromaticContact CD2-CE1 3.61Å; W70-H73 AromaticContact CE3-CE1 3.94Å; W70-H73 AromaticContact CG-CE1 3.46Å; W70-H73 VanDerWaalsContact CG-CE1 3.46Å; W70-H73 AromaticContact CG-ND1 3.88Å; W70-H73 VanDerWaalsContact O-CB 3.28Å; W70-H73 WeakPolarHBondContact O-CB 3.32Å; W70-H73 VanDerWaalsContact O-CG 3.3Å; W70-H73 PolarHBondContact O-N 3.42Å; F71-H73 PolarHBondContact O-N 3.37Å; H73-Y75 VanDerWaalsContact C-N 3.31Å; H73-Y75 PolarHBondContact O-N 3.5Å; H73-A76 PolarHBondContact O-N 3.13Å; H73-I77 WeakPolarHBondContact O-CG1 3.36Å; H73-I77 PolarHBondContact O-N 3.29Å; H73-Y163 HydrophobicContact CB-CE2 4.35Å; H73-Y163 AromaticContact ND1-CE2 3.9Å; H73-Y163 AromaticContact ND1-CZ 3.74Å; H73-Y163 PolarHBondContact ND1-OH 3.49Å; H73-L167 HydrophobicContact CB-CD2 4.26Å
74	F	96.1	Very high	92.5	Very high	12 Å²	12	50.5 Å²	50.5	5%	0.053	24%	0.239	C	C	.	.	H	α-helix	trans	-59.1	-45.2	179.4	-55.2	-39.6	0	0	0	111.8	F71 W72 S78 M158 Y163 L167 Y170	F71-F74 AromaticContact CD2-CD2 3.62Å; F71-F74 HydrophobicContact CD2-CD2 3.62Å; F71-F74 AromaticContact CD2-CE2 3.46Å; F71-F74 HydrophobicContact CD2-CE2 3.46Å; F71-F74 VanDerWaalsContact CD2-CE2 3.46Å; F71-F74 AromaticContact CE2-CD2 3.79Å; F71-F74 HydrophobicContact CE2-CD2 3.79Å; F71-F74 AromaticContact CE2-CE2 3.72Å; F71-F74 HydrophobicContact CE2-CE2 3.72Å; F71-F74 HydrophobicContact CG-CD2 4.15Å; F71-F74 HydrophobicContact CG-CE2 4.32Å; F71-F74 HydrophobicContact CZ-CD2 4.46Å; F71-F74 WeakPolarHBondContact O-CD2 3.22Å; F71-F74 PolarHBondContact O-N 3.06Å; W72-F74 VanDerWaalsContact C-N 3.26Å; W72-F74 PolarHBondContact O-N 2.88Å; F74-S78 WeakPolarHBondContact O-CB 3.39Å; F74-S78 PolarHBondContact O-N 3.08Å; F74-M158 HydrophobicContact CE2-CE 4.15Å; F74-M158 HydrophobicContact CE2-SD 4.05Å; F74-M158 HydrophobicContact CZ-CE 4.39Å; F74-M158 HydrophobicContact CZ-SD 3.71Å; F74-Y163 HydrophobicContact CD1-CE2 4.49Å; F74-Y163 AromaticContact CE1-CD2 3.41Å; F74-Y163 HydrophobicContact CE1-CD2 3.41Å; F74-Y163 VanDerWaalsContact CE1-CD2 3.41Å; F74-Y163 AromaticContact CE1-CE2 3.67Å; F74-Y163 HydrophobicContact CE1-CE2 3.67Å; F74-Y163 HydrophobicContact CE1-CG 4.13Å; F74-Y163 WeakPolarHBondContact CE1-O 3.24Å; F74-Y163 AromaticContact CZ-CD2 3.46Å; F74-Y163 HydrophobicContact CZ-CD2 3.46Å; F74-Y163 VanDerWaalsContact CZ-CD2 3.46Å; F74-Y163 HydrophobicContact CZ-CE2 4.05Å; F74-Y163 HydrophobicContact CZ-CG 4.26Å; F74-L167 HydrophobicContact CD1-CD2 3.49Å; F74-L167 VanDerWaalsContact CD1-CD2 3.49Å; F74-L167 HydrophobicContact CD1-CG 4Å; F74-L167 HydrophobicContact CE1-CD2 3.86Å; F74-L167 HydrophobicContact CE1-CG 4Å; F74-Y170 HydrophobicContact CB-CD2 3.88Å; F74-Y170 HydrophobicContact CB-CE2 3.59Å; F74-Y170 WeakPolarHBondContact O-CD2 3.06Å
75	Y	96.9	Very high	93.2	Very high	8 Å²	8	46.1 Å²	46.1	3%	0.031	22%	0.22	C	C	.	.	H	α-helix	trans	-75.2	-33.6	-179.8	-59.3	-64.7	0	0	0	112.3	F71 W72 H73 S78 V79 R143 C147 Y170	F71-Y75 HydrophobicContact CD1-CD2 4.47Å; F71-Y75 AromaticContact CD1-CE2 3.64Å; F71-Y75 HydrophobicContact CD1-CE2 3.64Å; F71-Y75 AromaticContact CE1-CE2 3.47Å; F71-Y75 HydrophobicContact CE1-CE2 3.47Å; F71-Y75 VanDerWaalsContact CE1-CE2 3.47Å; F71-Y75 AromaticContact CE1-CZ 3.83Å; F71-Y75 WeakPolarHBondContact CE1-OH 3.45Å; F71-Y75 HydrophobicContact CZ-CE2 4.43Å; W72-Y75 PolarHBondContact O-N 3.44Å; H73-Y75 VanDerWaalsContact C-N 3.31Å; H73-Y75 PolarHBondContact O-N 3.5Å; Y75-S78 PolarHBondContact O-N 3.06Å; Y75-V79 VanDerWaalsContact O-CG2 3.27Å; Y75-V79 WeakPolarHBondContact O-CG2 3.47Å; Y75-V79 PolarHBondContact O-N 3.15Å; Y75-R143 HydrophobicContact CD1-CB 3.41Å; Y75-R143 VanDerWaalsContact CD1-CB 3.41Å; Y75-R143 HydrophobicContact CD1-CG 4.23Å; Y75-R143 HydrophobicContact CD2-CB 4.05Å; Y75-R143 HydrophobicContact CE1-CB 3.35Å; Y75-R143 HydrophobicContact CE1-CG 3.76Å; Y75-R143 HydrophobicContact CE2-CB 3.99Å; Y75-R143 HydrophobicContact CG-CB 3.76Å; Y75-R143 PolarHBondContact OH-NE 3.36Å; Y75-R143 VanDerWaalsContact OH-NE 3.08Å; Y75-R143 PolarHBondContact OH-NH2 2.94Å; Y75-R143 VanDerWaalsContact OH-NH2 3.07Å; Y75-C147 VanDerWaalsContact CE2-SG 3.57Å; Y75-Y170 HydrophobicContact CD1-CE1 4.49Å; Y75-Y170 AromaticContact CE1-CZ 3.84Å; Y75-Y170 WeakPolarHBondContact CE1-OH 3.32Å
76	A	97.6	Very high	93.8	Very high	22 Å²	22	44.6 Å²	44.6	18%	0.182	21%	0.211	C	C	.	.	H	α-helix	trans	-61	-47.1	172.8	0	0	0	0	0	111.5	W72 H73 S78 V79 C80 L144	W72-A76 HydrophobicContact CE3-CB 3.9Å; W72-A76 HydrophobicContact CZ3-CB 3.89Å; W72-A76 PolarHBondContact O-N 2.88Å; H73-A76 PolarHBondContact O-N 3.13Å; A76-S78 VanDerWaalsContact C-N 3.34Å; A76-S78 PolarHBondContact O-N 3.28Å; A76-V79 PolarHBondContact O-N 3.3Å; A76-C80 PolarHBondContact O-N 3.26Å; A76-C80 PolarHBondContact O-SG 3.42Å; A76-L144 HydrophobicContact CB-CD1 4.18Å; A76-L144 HydrophobicContact CB-CD2 4.45Å
77	I	97.8	Very high	94.3	Very high	59 Å²	59	49.3 Å²	49.3	30%	0.303	24%	0.236	S	C	.	.	H	α-helix	trans	-60.6	-45.5	174.2	-69.4	-172.1	0	0	0	110.7	H73 V79 C80 W81 L167 I171	H73-I77 WeakPolarHBondContact O-CG1 3.36Å; H73-I77 PolarHBondContact O-N 3.29Å; I77-V79 PolarHBondContact O-N 2.8Å; I77-C80 PolarHBondContact O-N 3.4Å; I77-W81 WeakPolarHBondContact O-CB 3.4Å; I77-W81 PolarHBondContact O-N 3.47Å; I77-L167 HydrophobicContact CD1-CB 4.2Å; I77-L167 HydrophobicContact CD1-CD1 4.48Å; I77-L167 HydrophobicContact CD1-CD2 3.41Å; I77-L167 VanDerWaalsContact CD1-CD2 3.41Å; I77-L167 HydrophobicContact CD1-CG 4.2Å; I77-L167 HydrophobicContact CG1-CD2 4.37Å; I77-I171 HydrophobicContact CG2-CD1 3.67Å; I77-I171 HydrophobicContact CG2-CG1 4.27Å
78	S	97.4	Very high	94.8	Very high	2 Å²	2	48.5 Å²	48.5	1%	0.014	23%	0.228	C	C	.	.	H	α-helix	trans	-59.2	-45	179.1	-172.3	0	0	0	0	112.8	F74 Y75 A76 N82 S140 Y170	F74-S78 WeakPolarHBondContact O-CB 3.39Å; F74-S78 PolarHBondContact O-N 3.08Å; Y75-S78 PolarHBondContact O-N 3.06Å; A76-S78 VanDerWaalsContact C-N 3.34Å; A76-S78 PolarHBondContact O-N 3.28Å; S78-N82 WeakPolarHBondContact O-CB 3.44Å; S78-N82 PolarHBondContact O-N 3.12Å; S78-N82 PolarHBondContact O-ND2 3.26Å; S78-N82 PolarHBondContact OG-ND2 3.19Å; S78-N82 VanDerWaalsContact OG-ND2 3.14Å; S78-S140 VanDerWaalsContact OG-CB 3.3Å; S78-S140 WeakPolarHBondContact OG-CB 3.13Å; S78-Y170 WeakPolarHBondContact OG-CD1 3.35Å
79	V	98.1	Very high	95.2	Very high	13 Å²	13	46.1 Å²	46.1	8%	0.079	22%	0.218	C	C	.	.	H	α-helix	trans	-62.6	-52.8	178	170.2	0	0	0	0	110.2	Y75 A76 I77 W81 N82 I83 S140 L141 L144	Y75-V79 VanDerWaalsContact O-CG2 3.27Å; Y75-V79 WeakPolarHBondContact O-CG2 3.47Å; Y75-V79 PolarHBondContact O-N 3.15Å; A76-V79 PolarHBondContact O-N 3.3Å; I77-V79 PolarHBondContact O-N 2.8Å; V79-W81 VanDerWaalsContact C-N 3.31Å; V79-W81 PolarHBondContact O-N 3.01Å; V79-N82 PolarHBondContact O-N 2.86Å; V79-I83 HydrophobicContact CG1-CD1 3.59Å; V79-I83 HydrophobicContact CG1-CG1 4.37Å; V79-I83 WeakPolarHBondContact O-CB 3.28Å; V79-I83 VanDerWaalsContact O-CG1 3.24Å; V79-I83 WeakPolarHBondContact O-CG1 3.45Å; V79-I83 PolarHBondContact O-N 2.86Å; V79-S140 WeakPolarHBondContact CG2-OG 3.43Å; V79-L141 HydrophobicContact CG2-CB 4.02Å; V79-L144 HydrophobicContact CG2-CD2 4.26Å
80	C	98.1	Very high	95.5	Very high	88 Å²	88	43.6 Å²	43.6	60%	0.595	21%	0.211	S	C	*	.	H	α-helix	trans	-58.2	-44.4	-179.8	-67.8	0	0	0	0	111.8	A76 I77 F84	A76-C80 PolarHBondContact O-N 3.26Å; A76-C80 PolarHBondContact O-SG 3.42Å; I77-C80 PolarHBondContact O-N 3.4Å; C80-F84 WeakPolarHBondContact O-CB 3.28Å; C80-F84 PolarHBondContact O-N 2.93Å
81	W	98.1	Very high	95.5	Very high	39 Å²	39	40.8 Å²	40.8	15%	0.148	20%	0.204	C	C	.	.	H	α-helix	trans	-66.6	-47.8	-179.6	-176.9	-120.8	0	0	0	112.6	I77 V79 F84 L85 W102 I171 L175	I77-W81 WeakPolarHBondContact O-CB 3.4Å; I77-W81 PolarHBondContact O-N 3.47Å; V79-W81 VanDerWaalsContact C-N 3.31Å; V79-W81 PolarHBondContact O-N 3.01Å; W81-F84 AromaticContact CE3-CD1 3.98Å; W81-F84 HydrophobicContact CE3-CD1 3.98Å; W81-F84 AromaticContact CZ3-CD1 3.72Å; W81-F84 HydrophobicContact CZ3-CD1 3.72Å; W81-F84 AromaticContact CZ3-CE1 4Å; W81-F84 HydrophobicContact CZ3-CE1 4Å; W81-F84 WeakPolarHBondContact O-CB 3.42Å; W81-F84 PolarHBondContact O-N 3.4Å; W81-L85 HydrophobicContact CD2-CD1 4.46Å; W81-L85 HydrophobicContact CD2-CG 4.3Å; W81-L85 HydrophobicContact CH2-CD2 4.1Å; W81-L85 HydrophobicContact CZ2-CD1 4.17Å; W81-L85 HydrophobicContact CZ2-CD2 3.84Å; W81-L85 HydrophobicContact CZ2-CG 4.22Å; W81-L85 WeakPolarHBondContact O-CG 3.35Å; W81-L85 PolarHBondContact O-N 2.84Å; W81-W102 AromaticContact CH2-CH2 3.83Å; W81-W102 HydrophobicContact CH2-CH2 3.83Å; W81-W102 HydrophobicContact CH2-CZ3 4.13Å; W81-W102 HydrophobicContact CZ3-CH2 4.33Å; W81-I171 HydrophobicContact CB-CD1 3.89Å; W81-I171 HydrophobicContact CD2-CD1 3.77Å; W81-I171 HydrophobicContact CE3-CD1 4.28Å; W81-I171 HydrophobicContact CG-CD1 3.58Å; W81-I171 HydrophobicContact CZ2-CG2 4.06Å; W81-I171 PolarHBondContact NE1-O 3.38Å; W81-L175 HydrophobicContact CZ2-CD1 4.48Å; W81-L175 HydrophobicContact CZ2-CD2 3.86Å; W81-L175 HydrophobicContact CZ2-CG 3.99Å
82	N	96.9	Very high	95.6	Very high	1 Å²	1	38.9 Å²	38.9	1%	0.005	20%	0.195	C	C	.	.	H	α-helix	trans	-68.1	-36.4	-180	-73.5	-58.7	0	0	0	112.2	S78 V79 F84 L85 L86 C137	S78-N82 WeakPolarHBondContact O-CB 3.44Å; S78-N82 PolarHBondContact O-N 3.12Å; S78-N82 PolarHBondContact O-ND2 3.26Å; S78-N82 PolarHBondContact OG-ND2 3.19Å; S78-N82 VanDerWaalsContact OG-ND2 3.14Å; V79-N82 PolarHBondContact O-N 2.86Å; N82-F84 VanDerWaalsContact C-N 3.33Å; N82-L85 PolarHBondContact O-N 2.92Å; N82-L86 WeakPolarHBondContact O-CB 3.2Å; N82-L86 VanDerWaalsContact O-CG 3.28Å; N82-L86 WeakPolarHBondContact O-CG 3.35Å; N82-L86 PolarHBondContact O-N 3.02Å; N82-C137 HydrophobicContact CB-CB 4.18Å
83	I	97.7	Very high	95.3	Very high	75 Å²	75	37.3 Å²	37.3	39%	0.385	19%	0.193	S	C	.	.	H	α-helix	trans	-60.7	-46.2	171.7	-70.5	172.5	0	0	0	110	V79 L85 L86 L87 C137	V79-I83 HydrophobicContact CG1-CD1 3.59Å; V79-I83 HydrophobicContact CG1-CG1 4.37Å; V79-I83 WeakPolarHBondContact O-CB 3.28Å; V79-I83 VanDerWaalsContact O-CG1 3.24Å; V79-I83 WeakPolarHBondContact O-CG1 3.45Å; V79-I83 PolarHBondContact O-N 2.86Å; I83-L85 PolarHBondContact O-N 3.39Å; I83-L86 PolarHBondContact O-N 3.05Å; I83-L87 HydrophobicContact CG2-CD1 4.02Å; I83-L87 HydrophobicContact CG2-CG 4.37Å; I83-L87 VanDerWaalsContact O-CG 3.32Å; I83-L87 WeakPolarHBondContact O-CG 3.46Å; I83-L87 PolarHBondContact O-N 3.4Å; I83-C137 VanDerWaalsContact CG1-SG 3.55Å
84	F	97.6	Very high	94.9	Very high	82 Å²	82	44 Å²	44	36%	0.36	22%	0.218	S	C	.	.	H	α-helix	trans	-60	-47.4	178.3	176.3	-109.5	0	0	0	112	C80 W81 N82 L86 L87 L88 W102	C80-F84 WeakPolarHBondContact O-CB 3.28Å; C80-F84 PolarHBondContact O-N 2.93Å; W81-F84 AromaticContact CE3-CD1 3.98Å; W81-F84 HydrophobicContact CE3-CD1 3.98Å; W81-F84 AromaticContact CZ3-CD1 3.72Å; W81-F84 HydrophobicContact CZ3-CD1 3.72Å; W81-F84 AromaticContact CZ3-CE1 4Å; W81-F84 HydrophobicContact CZ3-CE1 4Å; W81-F84 WeakPolarHBondContact O-CB 3.42Å; W81-F84 PolarHBondContact O-N 3.4Å; N82-F84 VanDerWaalsContact C-N 3.33Å; F84-L86 PolarHBondContact O-N 3.23Å; F84-L87 PolarHBondContact O-N 2.93Å; F84-L88 HydrophobicContact CD1-CD1 4.2Å; F84-L88 HydrophobicContact CE1-CD1 3.61Å; F84-L88 HydrophobicContact CE1-CG 4.42Å; F84-L88 HydrophobicContact CE2-CD1 4.3Å; F84-L88 HydrophobicContact CE2-CD2 4.46Å; F84-L88 HydrophobicContact CE2-CG 4.34Å; F84-L88 HydrophobicContact CZ-CD1 3.67Å; F84-L88 HydrophobicContact CZ-CD2 4.43Å; F84-L88 HydrophobicContact CZ-CG 4.2Å; F84-L88 WeakPolarHBondContact O-CG 3.47Å; F84-L88 PolarHBondContact O-N 2.93Å; F84-W102 AromaticContact CE1-CH2 3.85Å; F84-W102 HydrophobicContact CE1-CH2 3.85Å; F84-W102 AromaticContact CE1-CZ2 3.66Å; F84-W102 HydrophobicContact CE1-CZ2 3.66Å; F84-W102 AromaticContact CZ-CZ2 3.9Å; F84-W102 HydrophobicContact CZ-CZ2 3.9Å
85	L	96.5	Very high	94.5	Very high	0 Å²	0	48.9 Å²	48.9	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-62.2	-41.4	175.9	-65.7	-175.1	0	0	0	112.2	W81 N82 I83 L87 L88 S89 L103 L133 L178	W81-L85 HydrophobicContact CD2-CD1 4.46Å; W81-L85 HydrophobicContact CD2-CG 4.3Å; W81-L85 HydrophobicContact CH2-CD2 4.1Å; W81-L85 HydrophobicContact CZ2-CD1 4.17Å; W81-L85 HydrophobicContact CZ2-CD2 3.84Å; W81-L85 HydrophobicContact CZ2-CG 4.22Å; W81-L85 WeakPolarHBondContact O-CG 3.35Å; W81-L85 PolarHBondContact O-N 2.84Å; N82-L85 PolarHBondContact O-N 2.92Å; I83-L85 PolarHBondContact O-N 3.39Å; L85-L87 PolarHBondContact O-N 2.75Å; L85-L88 PolarHBondContact O-N 3.44Å; L85-S89 PolarHBondContact O-N 2.84Å; L85-S89 PolarHBondContact O-OG 3.35Å; L85-S89 VanDerWaalsContact O-OG 3.08Å; L85-L103 HydrophobicContact CD2-CD1 4.49Å; L85-L103 HydrophobicContact CD2-CD2 4.2Å; L85-L133 HydrophobicContact CB-CD1 4.4Å; L85-L133 HydrophobicContact CD1-CD2 4.37Å; L85-L178 HydrophobicContact CB-CD1 4.5Å; L85-L178 HydrophobicContact CD1-CD1 4.05Å; L85-L178 HydrophobicContact CD2-CD1 3.9Å; L85-L178 HydrophobicContact CG-CD1 4.37Å
86	L	95.7	Very high	93.7	Very high	11 Å²	11	53.6 Å²	53.6	6%	0.058	27%	0.267	C	S	.	.	H	α-helix	trans	-60.2	-44.1	175.4	-80.7	167	0	0	0	112.1	N82 I83 F84 L88 S89 F90 V130 L133 L134 C137	N82-L86 WeakPolarHBondContact O-CB 3.2Å; N82-L86 VanDerWaalsContact O-CG 3.28Å; N82-L86 WeakPolarHBondContact O-CG 3.35Å; N82-L86 PolarHBondContact O-N 3.02Å; I83-L86 PolarHBondContact O-N 3.05Å; F84-L86 PolarHBondContact O-N 3.23Å; L86-L88 VanDerWaalsContact C-N 3.32Å; L86-L88 PolarHBondContact O-N 2.98Å; L86-S89 PolarHBondContact O-N 3.3Å; L86-F90 HydrophobicContact CB-CD2 4.45Å; L86-F90 HydrophobicContact CB-CE2 4.31Å; L86-F90 HydrophobicContact CD2-CE2 4.31Å; L86-F90 WeakPolarHBondContact O-CB 3.2Å; L86-F90 WeakPolarHBondContact O-CD2 3.3Å; L86-F90 WeakPolarHBondContact O-CG 3.28Å; L86-F90 PolarHBondContact O-N 3.3Å; L86-V130 HydrophobicContact CD2-CG1 4.07Å; L86-L133 HydrophobicContact CD2-CB 3.58Å; L86-L133 HydrophobicContact CD2-CD1 4.42Å; L86-L133 HydrophobicContact CG-CB 3.92Å; L86-L134 HydrophobicContact CD1-CD1 4.4Å; L86-L134 HydrophobicContact CD2-CB 4.39Å; L86-C137 HydrophobicContact CD1-CB 3.95Å
87	L	95.4	Very high	92.8	Very high	110 Å²	110	57.7 Å²	57.7	58%	0.576	28%	0.282	S	S	*	.	H	α-helix	trans	-61.6	-42	177.2	-71.9	172.9	0	0	0	111.3	I83 F84 L85 N91	I83-L87 HydrophobicContact CG2-CD1 4.02Å; I83-L87 HydrophobicContact CG2-CG 4.37Å; I83-L87 VanDerWaalsContact O-CG 3.32Å; I83-L87 WeakPolarHBondContact O-CG 3.46Å; I83-L87 PolarHBondContact O-N 3.4Å; F84-L87 PolarHBondContact O-N 2.93Å; L85-L87 PolarHBondContact O-N 2.75Å; L87-N91 VanDerWaalsContact O-CB 3.28Å; L87-N91 WeakPolarHBondContact O-CB 3.34Å; L87-N91 PolarHBondContact O-N 2.7Å
88	L	94.3	Very high	92.1	Very high	30 Å²	30	57.1 Å²	57.1	16%	0.157	28%	0.283	C	S	.	.	H	α-helix	trans	-64	-43.1	174	-67.1	-178.8	0	0	0	111.8	F84 L85 L86 N91 F92 Y99 P100 W102 L103	F84-L88 HydrophobicContact CD1-CD1 4.2Å; F84-L88 HydrophobicContact CE1-CD1 3.61Å; F84-L88 HydrophobicContact CE1-CG 4.42Å; F84-L88 HydrophobicContact CE2-CD1 4.3Å; F84-L88 HydrophobicContact CE2-CD2 4.46Å; F84-L88 HydrophobicContact CE2-CG 4.34Å; F84-L88 HydrophobicContact CZ-CD1 3.67Å; F84-L88 HydrophobicContact CZ-CD2 4.43Å; F84-L88 HydrophobicContact CZ-CG 4.2Å; F84-L88 WeakPolarHBondContact O-CG 3.47Å; F84-L88 PolarHBondContact O-N 2.93Å; L85-L88 PolarHBondContact O-N 3.44Å; L86-L88 VanDerWaalsContact C-N 3.32Å; L86-L88 PolarHBondContact O-N 2.98Å; L88-N91 PolarHBondContact O-N 2.86Å; L88-F92 PolarHBondContact O-N 3.14Å; L88-Y99 HydrophobicContact CB-CD1 3.96Å; L88-Y99 HydrophobicContact CB-CE1 3.94Å; L88-P100 HydrophobicContact CD1-CG 4.34Å; L88-P100 HydrophobicContact CD2-CG 4.04Å; L88-W102 HydrophobicContact CD1-CZ2 4.44Å; L88-L103 HydrophobicContact CD1-CD2 3.66Å
89	S	91.9	Very high	91.7	Very high	0 Å²	0	57.7 Å²	57.7	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-64	-42.1	177.7	-63.8	0	0	0	0	112.1	L85 L86 F92 I93 Y99	L85-S89 PolarHBondContact O-N 2.84Å; L85-S89 PolarHBondContact O-OG 3.35Å; L85-S89 VanDerWaalsContact O-OG 3.08Å; L86-S89 PolarHBondContact O-N 3.3Å; S89-F92 PolarHBondContact O-N 3.36Å; S89-I93 WeakPolarHBondContact O-CG1 3.45Å; S89-I93 PolarHBondContact O-N 2.93Å; S89-Y99 PolarHBondContact OG-OH 3.08Å
90	F	91.6	Very high	91.4	Very high	78 Å²	78	58.9 Å²	58.9	34%	0.342	29%	0.293	S	S	.	.	H	α-helix	trans	-65.8	-43.3	174.4	-74.5	-51.4	0	0	0	111.6	L86 F92 I93 Y94 V130	L86-F90 HydrophobicContact CB-CD2 4.45Å; L86-F90 HydrophobicContact CB-CE2 4.31Å; L86-F90 HydrophobicContact CD2-CE2 4.31Å; L86-F90 WeakPolarHBondContact O-CB 3.2Å; L86-F90 WeakPolarHBondContact O-CD2 3.3Å; L86-F90 WeakPolarHBondContact O-CG 3.28Å; L86-F90 PolarHBondContact O-N 3.3Å; F90-F92 VanDerWaalsContact C-N 3.26Å; F90-F92 PolarHBondContact O-N 3.44Å; F90-I93 PolarHBondContact O-N 2.73Å; F90-Y94 HydrophobicContact CB-CD2 4.1Å; F90-Y94 HydrophobicContact CB-CE2 4.2Å; F90-Y94 HydrophobicContact CD1-CD2 4.41Å; F90-Y94 AromaticContact CD1-CE2 3.75Å; F90-Y94 HydrophobicContact CD1-CE2 3.75Å; F90-Y94 HydrophobicContact CG-CE2 4.31Å; F90-Y94 WeakPolarHBondContact O-CB 3.32Å; F90-Y94 WeakPolarHBondContact O-CD2 3.38Å; F90-Y94 PolarHBondContact O-N 2.87Å; F90-V130 HydrophobicContact CE1-CG1 3.9Å; F90-V130 HydrophobicContact CZ-CG1 4.01Å
91	N	90.8	Very high	91	Very high	47 Å²	47	60 Å²	60	25%	0.251	30%	0.299	S	S	.	.	H	α-helix	trans	-58	-41.7	175.7	-174.8	-87.4	0	0	0	111.2	L87 L88 Q95 Q97	L87-N91 VanDerWaalsContact O-CB 3.28Å; L87-N91 WeakPolarHBondContact O-CB 3.34Å; L87-N91 PolarHBondContact O-N 2.7Å; L88-N91 PolarHBondContact O-N 2.86Å; N91-Q95 PolarHBondContact ND2-NE2 2.88Å; N91-Q95 PolarHBondContact ND2-OE1 3.1Å; N91-Q95 WeakPolarHBondContact O-CA 3.33Å; N91-Q95 VanDerWaalsContact O-CB 3.25Å; N91-Q95 WeakPolarHBondContact O-CB 3.44Å; N91-Q95 PolarHBondContact O-N 2.92Å; N91-Q97 WeakPolarHBondContact OD1-CB 3.45Å; N91-Q97 PolarHBondContact OD1-OE1 2.84Å
92	F	89.1	Confident	90.7	Very high	4 Å²	4	63.7 Å²	63.7	2%	0.018	31%	0.313	C	S	.	.	H	α-helix	trans	-61.5	-51.1	173.7	-161.1	161.7	0	0	0	111.9	L88 S89 F90 Y94 L96 Q97 Y99 L122 P124	L88-F92 PolarHBondContact O-N 3.14Å; S89-F92 PolarHBondContact O-N 3.36Å; F90-F92 VanDerWaalsContact C-N 3.26Å; F90-F92 PolarHBondContact O-N 3.44Å; F92-Y94 PolarHBondContact O-N 2.91Å; F92-L96 WeakPolarHBondContact O-CA 3.27Å; F92-L96 PolarHBondContact O-N 3.44Å; F92-Q97 WeakPolarHBondContact CA-O 3.19Å; F92-Q97 VanDerWaalsContact CB-O 3.27Å; F92-Q97 WeakPolarHBondContact CB-O 3.28Å; F92-Q97 WeakPolarHBondContact CD2-O 3.41Å; F92-Q97 WeakPolarHBondContact CG-O 3.31Å; F92-Y99 HydrophobicContact CD1-CD1 4.2Å; F92-Y99 AromaticContact CD1-CD2 3.88Å; F92-Y99 HydrophobicContact CD1-CD2 3.88Å; F92-Y99 HydrophobicContact CD1-CE1 4.15Å; F92-Y99 AromaticContact CD1-CE2 3.81Å; F92-Y99 HydrophobicContact CD1-CE2 3.81Å; F92-Y99 HydrophobicContact CD1-CG 4.06Å; F92-Y99 AromaticContact CD1-CZ 3.96Å; F92-Y99 AromaticContact CE1-CD2 3.93Å; F92-Y99 HydrophobicContact CE1-CD2 3.93Å; F92-Y99 HydrophobicContact CE1-CE2 4.08Å; F92-Y99 HydrophobicContact CE1-CG 4.37Å; F92-L122 HydrophobicContact CE1-CB 3.88Å; F92-L122 HydrophobicContact CZ-CB 3.91Å; F92-L122 WeakPolarHBondContact CZ-O 3.46Å; F92-P124 HydrophobicContact CD2-CB 4.32Å; F92-P124 HydrophobicContact CD2-CG 4.22Å; F92-P124 HydrophobicContact CE2-CB 4.46Å; F92-P124 HydrophobicContact CE2-CG 4.05Å
93	I	87.4	Confident	90.5	Very high	63 Å²	63	63.6 Å²	63.6	32%	0.323	31%	0.313	S	S	.	.	H	α-helix	trans	-61.2	-46	-178	-69.7	166.3	0	0	0	111.8	S89 F90 P124 P125 V130	S89-I93 WeakPolarHBondContact O-CG1 3.45Å; S89-I93 PolarHBondContact O-N 2.93Å; F90-I93 PolarHBondContact O-N 2.73Å; I93-P124 HydrophobicContact CG1-CB 4.35Å; I93-P125 HydrophobicContact CD1-CG 4Å; I93-P125 HydrophobicContact CG1-CG 4.07Å; I93-V130 HydrophobicContact CD1-CG2 3.75Å
94	Y	88.1	Confident	90.1	Very high	179 Å²	179	61.2 Å²	61.2	70%	0.702	30%	0.301	S	S	*	.	H	α-helix	trans	-85.5	-38.5	-172.8	-70.1	-66.8	0	0	0	113.8	F90 F92	F90-Y94 HydrophobicContact CB-CD2 4.1Å; F90-Y94 HydrophobicContact CB-CE2 4.2Å; F90-Y94 HydrophobicContact CD1-CD2 4.41Å; F90-Y94 AromaticContact CD1-CE2 3.75Å; F90-Y94 HydrophobicContact CD1-CE2 3.75Å; F90-Y94 HydrophobicContact CG-CE2 4.31Å; F90-Y94 WeakPolarHBondContact O-CB 3.32Å; F90-Y94 WeakPolarHBondContact O-CD2 3.38Å; F90-Y94 PolarHBondContact O-N 2.87Å; F92-Y94 PolarHBondContact O-N 2.91Å
95	Q	87	Confident	89.7	Confident	116 Å²	116	58.4 Å²	58.4	54%	0.542	30%	0.296	S	S	.	.	H	α-helix	trans	-101.8	-2.2	-175.3	-54.2	-173.5	4.9	0	0	112.7	N91 Q97	N91-Q95 PolarHBondContact ND2-NE2 2.88Å; N91-Q95 PolarHBondContact ND2-OE1 3.1Å; N91-Q95 WeakPolarHBondContact O-CA 3.33Å; N91-Q95 VanDerWaalsContact O-CB 3.25Å; N91-Q95 WeakPolarHBondContact O-CB 3.44Å; N91-Q95 PolarHBondContact O-N 2.92Å; Q95-Q97 HydrophobicContact CB-CG 4.01Å; Q95-Q97 PolarHBondContact O-N 2.87Å; Q95-Q97 VanDerWaalsContact O-N 3.09Å
96	L	79.9	Confident	89.5	Confident	107 Å²	107	61.4 Å²	61.4	56%	0.56	31%	0.311	S	S	*	.			trans	54.5	25	-175.7	-59.2	172.9	0	0	0	113.1	F92	F92-L96 WeakPolarHBondContact O-CA 3.27Å; F92-L96 PolarHBondContact O-N 3.44Å
97	Q	80.6	Confident	89.3	Confident	107 Å²	107	61 Å²	61	50%	0.5	31%	0.309	S	S	.	.	P	Polyproline II helix	trans	-85.7	122	175.1	-68.8	-168.4	-4.2	0	0	109.5	N91 F92 Q95	N91-Q97 WeakPolarHBondContact OD1-CB 3.45Å; N91-Q97 PolarHBondContact OD1-OE1 2.84Å; F92-Q97 WeakPolarHBondContact CA-O 3.19Å; F92-Q97 VanDerWaalsContact CB-O 3.27Å; F92-Q97 WeakPolarHBondContact CB-O 3.28Å; F92-Q97 WeakPolarHBondContact CD2-O 3.41Å; F92-Q97 WeakPolarHBondContact CG-O 3.31Å; Q95-Q97 HydrophobicContact CB-CG 4.01Å; Q95-Q97 PolarHBondContact O-N 2.87Å; Q95-Q97 VanDerWaalsContact O-N 3.09Å
98	S	82.9	Confident	89	Confident	47 Å²	47	58.8 Å²	58.8	33%	0.329	30%	0.296	S	S	.	.	P	Polyproline II helix	trans	-57.8	155	173.6	-59	0	0	0	0	111.1
99	Y	88.9	Confident	88.9	Confident	15 Å²	15	63 Å²	63	6%	0.059	32%	0.317	C	S	.	.	P	Polyproline II helix	trans	-51.9	150.2	170.6	-69.4	-54	0	0	0	111.6	L88 S89 F92 L103 L107 L122 P125 L178	L88-Y99 HydrophobicContact CB-CD1 3.96Å; L88-Y99 HydrophobicContact CB-CE1 3.94Å; S89-Y99 PolarHBondContact OG-OH 3.08Å; F92-Y99 HydrophobicContact CD1-CD1 4.2Å; F92-Y99 AromaticContact CD1-CD2 3.88Å; F92-Y99 HydrophobicContact CD1-CD2 3.88Å; F92-Y99 HydrophobicContact CD1-CE1 4.15Å; F92-Y99 AromaticContact CD1-CE2 3.81Å; F92-Y99 HydrophobicContact CD1-CE2 3.81Å; F92-Y99 HydrophobicContact CD1-CG 4.06Å; F92-Y99 AromaticContact CD1-CZ 3.96Å; F92-Y99 AromaticContact CE1-CD2 3.93Å; F92-Y99 HydrophobicContact CE1-CD2 3.93Å; F92-Y99 HydrophobicContact CE1-CE2 4.08Å; F92-Y99 HydrophobicContact CE1-CG 4.37Å; Y99-L103 HydrophobicContact CD1-CD2 3.8Å; Y99-L103 HydrophobicContact CE1-CD2 4.41Å; Y99-L103 HydrophobicContact CG-CD2 3.94Å; Y99-L103 HydrophobicContact CG-CG 4.5Å; Y99-L107 HydrophobicContact CD2-CD1 4.31Å; Y99-L122 HydrophobicContact CD2-CD2 3.86Å; Y99-L122 HydrophobicContact CE2-CD2 4.29Å; Y99-P125 WeakPolarHBondContact OH-CG 3.35Å; Y99-L178 WeakPolarHBondContact OH-CD2 3.42Å
100	P	90.8	Very high	89	Confident	37 Å²	37	64.1 Å²	64.1	24%	0.24	32%	0.323	C	S	.	.	P	Polyproline II helix	trans	-52.6	146.5	175.1	-27.4	35	0	0	0	112.2	L88 W102 L103 T104	L88-P100 HydrophobicContact CD1-CG 4.34Å; L88-P100 HydrophobicContact CD2-CG 4.04Å; P100-W102 HydrophobicContact CB-CG 4.39Å; P100-W102 VanDerWaalsContact CB-NE1 3.29Å; P100-W102 PolarHBondContact O-N 3.33Å; P100-W102 VanDerWaalsContact O-N 3.1Å; P100-L103 WeakPolarHBondContact O-CB 3.27Å; P100-L103 PolarHBondContact O-N 3.24Å; P100-T104 PolarHBondContact O-N 3.05Å; P100-T104 VanDerWaalsContact O-N 3.08Å
101	P	89.4	Confident	88.8	Confident	112 Å²	112	60.8 Å²	60.8	73%	0.727	31%	0.309	S	S	*	.	H	α-helix	trans	-56.6	-32.5	-174.9	-27.7	34.7	0	0	0	114.8	L103 T104 G105	P101-L103 VanDerWaalsContact C-N 3.33Å; P101-T104 WeakPolarHBondContact CA-OG1 3.37Å; P101-T104 PolarHBondContact O-OG1 3.43Å; P101-G105 PolarHBondContact O-N 2.99Å
102	W	92.6	Very high	88.6	Confident	116 Å²	116	61.3 Å²	61.3	44%	0.439	33%	0.326	S	S	.	.	H	α-helix	trans	-66.5	-36.7	176.6	69.3	-98.1	0	0	0	111.6	W81 F84 L88 P100 I106	W81-W102 AromaticContact CH2-CH2 3.83Å; W81-W102 HydrophobicContact CH2-CH2 3.83Å; W81-W102 HydrophobicContact CH2-CZ3 4.13Å; W81-W102 HydrophobicContact CZ3-CH2 4.33Å; F84-W102 AromaticContact CE1-CH2 3.85Å; F84-W102 HydrophobicContact CE1-CH2 3.85Å; F84-W102 AromaticContact CE1-CZ2 3.66Å; F84-W102 HydrophobicContact CE1-CZ2 3.66Å; F84-W102 AromaticContact CZ-CZ2 3.9Å; F84-W102 HydrophobicContact CZ-CZ2 3.9Å; L88-W102 HydrophobicContact CD1-CZ2 4.44Å; P100-W102 HydrophobicContact CB-CG 4.39Å; P100-W102 VanDerWaalsContact CB-NE1 3.29Å; P100-W102 PolarHBondContact O-N 3.33Å; P100-W102 VanDerWaalsContact O-N 3.1Å; W102-I106 HydrophobicContact CE3-CD1 3.75Å; W102-I106 HydrophobicContact CZ3-CD1 3.96Å; W102-I106 VanDerWaalsContact O-CG1 3.31Å; W102-I106 WeakPolarHBondContact O-CG1 3.43Å; W102-I106 PolarHBondContact O-N 3.19Å; W102-I106 VanDerWaalsContact O-N 3.14Å
103	L	92.1	Very high	88.1	Confident	0 Å²	0	64.3 Å²	64.3	0%	0	34%	0.344	C	S	.	.	H	α-helix	trans	-76.1	-43.1	-179.2	180	56.9	0	0	0	110.1	L85 L88 Y99 P100 P101 G105 I106 L107 L175 L178	L85-L103 HydrophobicContact CD2-CD1 4.49Å; L85-L103 HydrophobicContact CD2-CD2 4.2Å; L88-L103 HydrophobicContact CD1-CD2 3.66Å; Y99-L103 HydrophobicContact CD1-CD2 3.8Å; Y99-L103 HydrophobicContact CE1-CD2 4.41Å; Y99-L103 HydrophobicContact CG-CD2 3.94Å; Y99-L103 HydrophobicContact CG-CG 4.5Å; P100-L103 WeakPolarHBondContact O-CB 3.27Å; P100-L103 PolarHBondContact O-N 3.24Å; P101-L103 VanDerWaalsContact C-N 3.33Å; L103-G105 VanDerWaalsContact C-N 3.33Å; L103-G105 PolarHBondContact O-N 3.4Å; L103-I106 PolarHBondContact O-N 3.07Å; L103-L107 HydrophobicContact CD1-CD1 4.42Å; L103-L107 HydrophobicContact CD1-CG 4.28Å; L103-L107 HydrophobicContact CG-CD1 4.24Å; L103-L107 VanDerWaalsContact O-CG 3.3Å; L103-L107 WeakPolarHBondContact O-CG 3.46Å; L103-L107 PolarHBondContact O-N 3.02Å; L103-L175 HydrophobicContact CD1-CD2 3.64Å; L103-L178 HydrophobicContact CD2-CD1 4.31Å
104	T	89.1	Confident	87.4	Confident	24 Å²	24	65.7 Å²	65.7	15%	0.147	36%	0.357	C	S	.	.	H	α-helix	trans	-59.4	-45	174.2	56.7	0	0	0	0	111.1	P100 P101 I106 L107 E108	P100-T104 PolarHBondContact O-N 3.05Å; P100-T104 VanDerWaalsContact O-N 3.08Å; P101-T104 WeakPolarHBondContact CA-OG1 3.37Å; P101-T104 PolarHBondContact O-OG1 3.43Å; T104-I106 VanDerWaalsContact C-N 3.34Å; T104-I106 PolarHBondContact O-N 3.12Å; T104-L107 PolarHBondContact O-N 3.4Å; T104-L107 VanDerWaalsContact O-N 3.16Å; T104-E108 VanDerWaalsContact O-CG 3.3Å; T104-E108 WeakPolarHBondContact O-CG 3.31Å; T104-E108 PolarHBondContact O-N 3.33Å
105	G	90	Very high	86.2	Confident	23 Å²	23	58.9 Å²	58.9	24%	0.237	34%	0.335	C	S	.	.	H	α-helix	trans	-59.6	-41	176.7	0	0	0	0	0	113.1	P101 L103 I109	P101-G105 PolarHBondContact O-N 2.99Å; L103-G105 VanDerWaalsContact C-N 3.33Å; L103-G105 PolarHBondContact O-N 3.4Å; G105-I109 WeakPolarHBondContact O-CD1 3.46Å; G105-I109 VanDerWaalsContact O-CG1 3.24Å; G105-I109 WeakPolarHBondContact O-CG1 3.34Å; G105-I109 PolarHBondContact O-N 3.38Å
106	I	93.1	Very high	84.5	Confident	63 Å²	63	58.1 Å²	58.1	32%	0.323	34%	0.343	S	S	.	.	H	α-helix	trans	-63.5	-47.2	174.1	-71.2	171.2	0	0	0	111	W102 L103 T104 E108 I109 L110 L175	W102-I106 HydrophobicContact CE3-CD1 3.75Å; W102-I106 HydrophobicContact CZ3-CD1 3.96Å; W102-I106 VanDerWaalsContact O-CG1 3.31Å; W102-I106 WeakPolarHBondContact O-CG1 3.43Å; W102-I106 PolarHBondContact O-N 3.19Å; W102-I106 VanDerWaalsContact O-N 3.14Å; L103-I106 PolarHBondContact O-N 3.07Å; T104-I106 VanDerWaalsContact C-N 3.34Å; T104-I106 PolarHBondContact O-N 3.12Å; I106-E108 VanDerWaalsContact C-N 3.32Å; I106-E108 PolarHBondContact O-N 3.47Å; I106-I109 PolarHBondContact O-N 3.34Å; I106-L110 HydrophobicContact CG2-CD1 3.75Å; I106-L110 HydrophobicContact CG2-CG 4.19Å; I106-L110 WeakPolarHBondContact O-CB 3.49Å; I106-L110 VanDerWaalsContact O-CG 3.26Å; I106-L110 WeakPolarHBondContact O-CG 3.3Å; I106-L110 PolarHBondContact O-N 3.32Å; I106-L175 HydrophobicContact CG2-CD1 3.94Å; I106-L175 HydrophobicContact CG2-CD2 4.25Å
107	L	91.3	Very high	82.7	Confident	3 Å²	3	63.4 Å²	63.4	2%	0.016	36%	0.362	C	S	.	.	H	α-helix	trans	-63.2	-38.2	-179.2	-66	175.2	0	0	0	111.9	Y99 L103 T104 L110 T111 L175 L178 L182	Y99-L107 HydrophobicContact CD2-CD1 4.31Å; L103-L107 HydrophobicContact CD1-CD1 4.42Å; L103-L107 HydrophobicContact CD1-CG 4.28Å; L103-L107 HydrophobicContact CG-CD1 4.24Å; L103-L107 VanDerWaalsContact O-CG 3.3Å; L103-L107 WeakPolarHBondContact O-CG 3.46Å; L103-L107 PolarHBondContact O-N 3.02Å; T104-L107 PolarHBondContact O-N 3.4Å; T104-L107 VanDerWaalsContact O-N 3.16Å; L107-L110 PolarHBondContact O-N 3.16Å; L107-T111 WeakPolarHBondContact O-CB 3.45Å; L107-T111 VanDerWaalsContact O-CG2 3.31Å; L107-T111 WeakPolarHBondContact O-CG2 3.49Å; L107-T111 PolarHBondContact O-N 3.33Å; L107-T111 PolarHBondContact O-OG1 3.49Å; L107-L175 HydrophobicContact CD2-CD2 4.32Å; L107-L178 HydrophobicContact CD1-CB 4.32Å; L107-L178 HydrophobicContact CD2-CB 3.86Å; L107-L182 HydrophobicContact CB-CD1 3.92Å; L107-L182 HydrophobicContact CD1-CD1 4.49Å
108	E	89.3	Confident	80.9	Confident	64 Å²	64	61.9 Å²	61.9	30%	0.299	38%	0.375	S	S	.	.	H	α-helix	trans	-62.3	-46.8	173.7	-73.5	171	-159.1	0	0	111.8	T104 I106 L110 T111 G112 S115	T104-E108 VanDerWaalsContact O-CG 3.3Å; T104-E108 WeakPolarHBondContact O-CG 3.31Å; T104-E108 PolarHBondContact O-N 3.33Å; I106-E108 VanDerWaalsContact C-N 3.32Å; I106-E108 PolarHBondContact O-N 3.47Å; E108-L110 VanDerWaalsContact C-N 3.33Å; E108-L110 PolarHBondContact O-N 3.38Å; E108-T111 PolarHBondContact O-N 2.95Å; E108-G112 VanDerWaalsContact O-CA 3.25Å; E108-G112 WeakPolarHBondContact O-CA 3.27Å; E108-G112 PolarHBondContact O-N 2.99Å; E108-S115 WeakPolarHBondContact OE1-CB 3.45Å; E108-S115 PolarHBondContact OE1-OG 3.31Å
109	I	92.4	Very high	78.8	Confident	117 Å²	117	68.2 Å²	68.2	60%	0.6	40%	0.399	S	S	*	.	H	α-helix	trans	-61.6	-43.5	177.1	-69.6	165.1	0	0	0	110.7	L4 G105 I106	L4-I109 HydrophobicContact CD2-CG2 3.95Å; G105-I109 WeakPolarHBondContact O-CD1 3.46Å; G105-I109 VanDerWaalsContact O-CG1 3.24Å; G105-I109 WeakPolarHBondContact O-CG1 3.34Å; G105-I109 PolarHBondContact O-N 3.38Å; I106-I109 PolarHBondContact O-N 3.34Å
110	L	92.6	Very high	76.7	Confident	25 Å²	25	70.5 Å²	70.5	13%	0.131	43%	0.428	C	S	.	.	H	α-helix	trans	-68.2	-41.8	-177.9	-73.3	179.3	0	0	0	112.5	L4 I5 I106 L107 E108 L175	L4-L110 HydrophobicContact CD2-CD2 4.45Å; L4-L110 PolarHBondContact N-O 3.25Å; I5-L110 HydrophobicContact CB-CB 4.26Å; I5-L110 HydrophobicContact CD1-CD2 4.37Å; I5-L110 WeakPolarHBondContact CG2-O 3.15Å; I5-L110 PolarHBondContact N-O 3.34Å; I106-L110 HydrophobicContact CG2-CD1 3.75Å; I106-L110 HydrophobicContact CG2-CG 4.19Å; I106-L110 WeakPolarHBondContact O-CB 3.49Å; I106-L110 VanDerWaalsContact O-CG 3.26Å; I106-L110 WeakPolarHBondContact O-CG 3.3Å; I106-L110 PolarHBondContact O-N 3.32Å; L107-L110 PolarHBondContact O-N 3.16Å; E108-L110 VanDerWaalsContact C-N 3.33Å; E108-L110 PolarHBondContact O-N 3.38Å; L110-L175 HydrophobicContact CD1-CB 4.01Å; L110-L175 HydrophobicContact CD1-CD1 4.13Å
111	T	88.6	Confident	75	Confident	8 Å²	8	75.8 Å²	75.8	5%	0.049	45%	0.447	C	S	.	.	H	α-helix	trans	-88.7	-23.4	-176.5	59.5	0	0	0	0	113.1	S3 L107 E108 V113 C179 L182 T183	S3-T111 VanDerWaalsContact CB-O 3.27Å; S3-T111 WeakPolarHBondContact CB-O 3.3Å; L107-T111 WeakPolarHBondContact O-CB 3.45Å; L107-T111 VanDerWaalsContact O-CG2 3.31Å; L107-T111 WeakPolarHBondContact O-CG2 3.49Å; L107-T111 PolarHBondContact O-N 3.33Å; L107-T111 PolarHBondContact O-OG1 3.49Å; E108-T111 PolarHBondContact O-N 2.95Å; T111-V113 PolarHBondContact O-N 2.94Å; T111-V113 PolarHBondContact OG1-N 3.45Å; T111-C179 HydrophobicContact CG2-CB 3.67Å; T111-L182 HydrophobicContact CG2-CB 4.02Å; T111-L182 HydrophobicContact CG2-CD1 4.01Å; T111-T183 HydrophobicContact CG2-CG2 4.01Å
112	G	85.6	Confident	73.9	Confident	58 Å²	58	71.7 Å²	71.7	60%	0.598	42%	0.419	S	S	*	.			trans	68	11.9	-169.2	0	0	0	0	0	113.3	E108 P114	E108-G112 VanDerWaalsContact O-CA 3.25Å; E108-G112 WeakPolarHBondContact O-CA 3.27Å; E108-G112 PolarHBondContact O-N 2.99Å; G112-P114 WeakPolarHBondContact O-CD 3.33Å
113	V	79.5	Confident	73	Confident	66 Å²	66	71 Å²	71	40%	0.4	43%	0.431	S	S	.	.			trans	-99.1	108.2	179.1	-178.2	0	0	0	0	107.7	T111 S115	T111-V113 PolarHBondContact O-N 2.94Å; T111-V113 PolarHBondContact OG1-N 3.45Å; V113-S115 PolarHBondContact O-N 3.49Å
114	P	71.4	Confident	72.4	Confident	93 Å²	93	73.9 Å²	73.9	60%	0.604	45%	0.45	S	S	*	.			trans	-66.1	133.4	176.2	24.1	-29.4	0	0	0	109.7	G112 S116	G112-P114 WeakPolarHBondContact O-CD 3.33Å; P114-S116 PolarHBondContact O-N 3.25Å; P114-S116 VanDerWaalsContact O-N 3.15Å
115	S	63.1	Low	72.2	Confident	35 Å²	35	73.3 Å²	73.3	25%	0.245	45%	0.447	C	S	.	.			trans	-55.1	120.8	163	-60.6	0	0	0	0	107.1	E108 V113 F117 L122	E108-S115 WeakPolarHBondContact OE1-CB 3.45Å; E108-S115 PolarHBondContact OE1-OG 3.31Å; V113-S115 PolarHBondContact O-N 3.49Å; S115-F117 PolarHBondContact O-N 3.26Å; S115-L122 VanDerWaalsContact OG-CD1 3.28Å; S115-L122 WeakPolarHBondContact OG-CD1 3.42Å
116	S	52.4	Low	72	Confident	100 Å²	100	76.8 Å²	76.8	70%	0.699	46%	0.457	S	S	*	.			trans	-46.6	108	-171.9	-58.1	0	0	0	0	111.7	P114 G118 Q119	P114-S116 PolarHBondContact O-N 3.25Å; P114-S116 VanDerWaalsContact O-N 3.15Å; S116-G118 PolarHBondContact O-N 2.79Å; S116-Q119 PolarHBondContact O-N 2.9Å
117	F	42.2	Very low	71.7	Confident	218 Å²	218	80.8 Å²	80.8	96%	0.956	48%	0.478	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.7	103.3	178.6	-136.1	-98.9	0	0	0	107.3	S115	S115-F117 PolarHBondContact O-N 3.26Å
118	G	41.8	Very low	71.6	Confident	75 Å²	75	81 Å²	81	77%	0.773	48%	0.48	S	S	*	.	T	Hydrogen-bonded Turn	trans	125	-15	175.5	0	0	0	0	0	117.4	S116	S116-G118 PolarHBondContact O-N 2.79Å
119	Q	38.7	Very low	71.7	Confident	180 Å²	180	78 Å²	78	84%	0.841	47%	0.466	S	S	*	.	T	Hydrogen-bonded Turn	trans	-135.9	17.8	174.2	-76.9	-165.5	1.1	0	0	115.6	S116 K121	S116-Q119 PolarHBondContact O-N 2.9Å; Q119-K121 VanDerWaalsContact C-N 3.29Å; Q119-K121 PolarHBondContact O-N 3.39Å
120	G	44.9	Very low	71.8	Confident	64 Å²	64	72.8 Å²	72.8	66%	0.66	44%	0.44	S	S	*	.			trans	55.9	16.4	141.3	0	0	0	0	0	120.7
121	K	55	Low	71.8	Confident	147 Å²	147	74.3 Å²	74.3	64%	0.639	45%	0.448	S	S	*	.			trans	-138.1	112.9	172.9	-81.6	-175.5	174.9	179.6	0	110.9	Q119	Q119-K121 VanDerWaalsContact C-N 3.29Å; Q119-K121 PolarHBondContact O-N 3.39Å
122	L	66.8	Low	72.2	Confident	26 Å²	26	73.9 Å²	73.9	14%	0.136	45%	0.445	C	S	.	.	P	Polyproline II helix	trans	-51.2	144.8	152.9	-117	70.2	0	0	0	107.6	F92 Y99 S115 L182	F92-L122 HydrophobicContact CE1-CB 3.88Å; F92-L122 HydrophobicContact CZ-CB 3.91Å; F92-L122 WeakPolarHBondContact CZ-O 3.46Å; Y99-L122 HydrophobicContact CD2-CD2 3.86Å; Y99-L122 HydrophobicContact CE2-CD2 4.29Å; S115-L122 VanDerWaalsContact OG-CD1 3.28Å; S115-L122 WeakPolarHBondContact OG-CD1 3.42Å; L122-L182 HydrophobicContact CD2-CD2 4.25Å; L122-L182 HydrophobicContact CG-CD2 4.14Å
123	S	72.7	Confident	72.6	Confident	101 Å²	101	71.1 Å²	71.1	71%	0.706	42%	0.417	S	S	*	.	P	Polyproline II helix	trans	-66.8	144.7	166.8	-62.5	0	0	0	0	108.9
124	P	79.6	Confident	73.5	Confident	61 Å²	61	71.9 Å²	71.9	40%	0.396	42%	0.418	S	S	.	.	P	Polyproline II helix	trans	-51.8	145.1	168.9	-25	33.8	0	0	0	110.7	F92 I93	F92-P124 HydrophobicContact CD2-CB 4.32Å; F92-P124 HydrophobicContact CD2-CG 4.22Å; F92-P124 HydrophobicContact CE2-CB 4.46Å; F92-P124 HydrophobicContact CE2-CG 4.05Å; I93-P124 HydrophobicContact CG1-CB 4.35Å
125	P	84.3	Confident	74.8	Confident	12 Å²	12	67.8 Å²	67.8	8%	0.078	39%	0.391	C	S	.	.	P	Polyproline II helix	trans	-59.9	145.2	-179	25.9	-35.2	0	0	0	111.3	I93 Y99 V130 D181	I93-P125 HydrophobicContact CD1-CG 4Å; I93-P125 HydrophobicContact CG1-CG 4.07Å; Y99-P125 WeakPolarHBondContact OH-CG 3.35Å; P125-V130 HydrophobicContact CB-CG2 4.2Å; P125-V130 HydrophobicContact CG-CG2 4.07Å; P125-D181 WeakPolarHBondContact CA-OD2 3.37Å; P125-D181 WeakPolarHBondContact CB-OD2 3.49Å
126	Q	86.5	Confident	76.4	Confident	97 Å²	97	66.3 Å²	66.3	45%	0.453	38%	0.38	S	S	.	.	P	Polyproline II helix	trans	-68.9	153	178.1	-59.8	-177.1	13.7	0	0	110.6	S128 T129 V130 D181	Q126-S128 PolarHBondContact O-N 3.24Å; Q126-T129 WeakPolarHBondContact O-CB 3.36Å; Q126-T129 PolarHBondContact O-N 3.15Å; Q126-V130 PolarHBondContact O-N 3.35Å; Q126-V130 VanDerWaalsContact O-N 3.12Å; Q126-D181 WeakPolarHBondContact CB-OD1 3.45Å; Q126-D181 VanDerWaalsContact CG-OD1 3.3Å; Q126-D181 WeakPolarHBondContact CG-OD1 3.24Å; Q126-D181 PolarHBondContact N-OD2 3.25Å
127	L	87.4	Confident	78.5	Confident	146 Å²	146	62.2 Å²	62.2	76%	0.764	35%	0.352	S	S	*	.	H	α-helix	trans	-57.2	-37.6	178.5	-178.8	62.9	0	0	0	112.5	T129 V130 L131	L127-T129 VanDerWaalsContact C-N 3.31Å; L127-T129 PolarHBondContact O-N 2.96Å; L127-V130 PolarHBondContact O-N 3.16Å; L127-L131 VanDerWaalsContact O-CB 3.25Å; L127-L131 WeakPolarHBondContact O-CB 3.42Å; L127-L131 PolarHBondContact O-N 3.49Å
128	S	89.3	Confident	81.2	Confident	7 Å²	7	55.4 Å²	55.4	5%	0.049	33%	0.328	C	S	.	.	H	α-helix	trans	-61	-38.7	176	40	0	0	0	0	112.6	Q126 L131 V132 T264	Q126-S128 PolarHBondContact O-N 3.24Å; S128-L131 PolarHBondContact O-N 3.2Å; S128-V132 WeakPolarHBondContact O-CB 3.4Å; S128-V132 WeakPolarHBondContact O-CG2 3.42Å; S128-V132 PolarHBondContact O-N 3.31Å; S128-T264 WeakPolarHBondContact CB-O 3.4Å
129	T	91.4	Very high	83.9	Confident	1 Å²	1	51.9 Å²	51.9	1%	0.006	29%	0.291	C	S	.	.	H	α-helix	trans	-70	-44.4	179.5	-67.6	0	0	0	0	111	Q126 L127 L131 V132 L133 V177 L178 D181	Q126-T129 WeakPolarHBondContact O-CB 3.36Å; Q126-T129 PolarHBondContact O-N 3.15Å; L127-T129 VanDerWaalsContact C-N 3.31Å; L127-T129 PolarHBondContact O-N 2.96Å; T129-L131 VanDerWaalsContact C-N 3.34Å; T129-L131 PolarHBondContact O-N 3.38Å; T129-V132 PolarHBondContact O-N 3.43Å; T129-L133 PolarHBondContact O-N 3.22Å; T129-V177 HydrophobicContact CG2-CG1 3.85Å; T129-V177 WeakPolarHBondContact CG2-O 3.37Å; T129-L178 HydrophobicContact CG2-CD2 4.25Å; T129-D181 WeakPolarHBondContact CB-OD1 3.46Å; T129-D181 VanDerWaalsContact CB-OD2 3.26Å; T129-D181 WeakPolarHBondContact CB-OD2 3.3Å; T129-D181 WeakPolarHBondContact CG2-OD2 3.21Å; T129-D181 PolarHBondContact OG1-OD1 3.34Å; T129-D181 PolarHBondContact OG1-OD2 3.19Å
130	V	93.1	Very high	86.7	Confident	9 Å²	9	43.4 Å²	43.4	6%	0.055	25%	0.252	C	S	.	.	H	α-helix	trans	-62.6	-42	173.1	179.3	0	0	0	0	111.2	L86 F90 I93 P125 Q126 L127 V132 L133 L134	L86-V130 HydrophobicContact CD2-CG1 4.07Å; F90-V130 HydrophobicContact CE1-CG1 3.9Å; F90-V130 HydrophobicContact CZ-CG1 4.01Å; I93-V130 HydrophobicContact CD1-CG2 3.75Å; P125-V130 HydrophobicContact CB-CG2 4.2Å; P125-V130 HydrophobicContact CG-CG2 4.07Å; Q126-V130 PolarHBondContact O-N 3.35Å; Q126-V130 VanDerWaalsContact O-N 3.12Å; L127-V130 PolarHBondContact O-N 3.16Å; V130-V132 PolarHBondContact O-N 3.41Å; V130-L133 PolarHBondContact O-N 3.25Å; V130-L134 WeakPolarHBondContact O-CB 3.34Å; V130-L134 PolarHBondContact O-N 3.17Å
131	L	93.7	Very high	89.2	Confident	56 Å²	56	44 Å²	44	29%	0.293	24%	0.239	S	C	.	.	H	α-helix	trans	-61.8	-43.7	177	179.7	60.2	0	0	0	111.5	L127 S128 T129 L134 L135 T264	L127-L131 VanDerWaalsContact O-CB 3.25Å; L127-L131 WeakPolarHBondContact O-CB 3.42Å; L127-L131 PolarHBondContact O-N 3.49Å; S128-L131 PolarHBondContact O-N 3.2Å; T129-L131 VanDerWaalsContact C-N 3.34Å; T129-L131 PolarHBondContact O-N 3.38Å; L131-L134 WeakPolarHBondContact O-CB 3.45Å; L131-L134 PolarHBondContact O-N 3.08Å; L131-L135 HydrophobicContact CD1-CG 4.43Å; L131-L135 HydrophobicContact CG-CD1 4.42Å; L131-L135 VanDerWaalsContact O-CG 3.31Å; L131-L135 WeakPolarHBondContact O-CG 3.41Å; L131-L135 PolarHBondContact O-N 3.18Å; L131-T264 HydrophobicContact CB-CG2 4.49Å; L131-T264 HydrophobicContact CD2-CG2 3.51Å; L131-T264 HydrophobicContact CG-CG2 3.81Å
132	V	95.9	Very high	91.3	Very high	0 Å²	0	39 Å²	39	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-67.7	-39.1	178.3	168.2	0	0	0	0	111.6	S128 T129 V130 L134 L135 L136 V177 L261 T264 L265 W272	S128-V132 WeakPolarHBondContact O-CB 3.4Å; S128-V132 WeakPolarHBondContact O-CG2 3.42Å; S128-V132 PolarHBondContact O-N 3.31Å; T129-V132 PolarHBondContact O-N 3.43Å; V130-V132 PolarHBondContact O-N 3.41Å; V132-L134 VanDerWaalsContact C-N 3.31Å; V132-L134 PolarHBondContact O-N 2.83Å; V132-L135 PolarHBondContact O-N 2.91Å; V132-L136 WeakPolarHBondContact O-CB 3.42Å; V132-L136 WeakPolarHBondContact O-CG 3.47Å; V132-L136 PolarHBondContact O-N 3.16Å; V132-V177 HydrophobicContact CB-CG1 4.1Å; V132-V177 HydrophobicContact CG1-CB 4.5Å; V132-V177 HydrophobicContact CG1-CG1 3.77Å; V132-V177 HydrophobicContact CG1-CG2 3.81Å; V132-L261 HydrophobicContact CG1-CB 4.32Å; V132-L261 HydrophobicContact CG1-CD2 4.22Å; V132-T264 HydrophobicContact CG2-CG2 3.68Å; V132-L265 HydrophobicContact CB-CD2 4.08Å; V132-L265 HydrophobicContact CB-CG 4.38Å; V132-L265 HydrophobicContact CG1-CD2 4.35Å; V132-L265 HydrophobicContact CG1-CG 4.35Å; V132-L265 HydrophobicContact CG2-CD2 3.71Å; V132-L265 HydrophobicContact CG2-CG 3.7Å; V132-W272 HydrophobicContact CG1-CH2 4.48Å
133	L	95.8	Very high	92.7	Very high	0 Å²	0	38.4 Å²	38.4	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-59.8	-41.9	170.5	-77.9	176	0	0	0	111.8	L85 L86 T129 V130 L136 C137 V177 L178	L85-L133 HydrophobicContact CB-CD1 4.4Å; L85-L133 HydrophobicContact CD1-CD2 4.37Å; L86-L133 HydrophobicContact CD2-CB 3.58Å; L86-L133 HydrophobicContact CD2-CD1 4.42Å; L86-L133 HydrophobicContact CG-CB 3.92Å; T129-L133 PolarHBondContact O-N 3.22Å; V130-L133 PolarHBondContact O-N 3.25Å; L133-L136 PolarHBondContact O-N 3.42Å; L133-C137 WeakPolarHBondContact O-CB 3.41Å; L133-C137 PolarHBondContact O-N 2.88Å; L133-V177 HydrophobicContact CD2-CB 3.9Å; L133-V177 HydrophobicContact CD2-CG1 3.9Å; L133-V177 HydrophobicContact CD2-CG2 4.44Å; L133-V177 HydrophobicContact CG-CB 4.25Å; L133-V177 HydrophobicContact CG-CG1 3.67Å; L133-L178 HydrophobicContact CD1-CD2 3.71Å; L133-L178 HydrophobicContact CD1-CG 4.38Å
134	L	97.2	Very high	93.9	Very high	81 Å²	81	34.7 Å²	34.7	42%	0.424	18%	0.184	S	C	.	.	H	α-helix	trans	-63.2	-46.2	176	179.7	64.1	0	0	0	111.3	L86 V130 L131 V132 L136 C137 V138	L86-L134 HydrophobicContact CD1-CD1 4.4Å; L86-L134 HydrophobicContact CD2-CB 4.39Å; V130-L134 WeakPolarHBondContact O-CB 3.34Å; V130-L134 PolarHBondContact O-N 3.17Å; L131-L134 WeakPolarHBondContact O-CB 3.45Å; L131-L134 PolarHBondContact O-N 3.08Å; V132-L134 VanDerWaalsContact C-N 3.31Å; V132-L134 PolarHBondContact O-N 2.83Å; L134-L136 VanDerWaalsContact C-N 3.34Å; L134-L136 PolarHBondContact O-N 3.26Å; L134-C137 WeakPolarHBondContact O-CB 3.42Å; L134-C137 PolarHBondContact O-N 3.43Å; L134-C137 VanDerWaalsContact O-N 3.15Å; L134-V138 WeakPolarHBondContact O-CG2 3.31Å; L134-V138 PolarHBondContact O-N 2.49Å
135	L	98.1	Very high	94.8	Very high	8 Å²	8	35.6 Å²	35.6	4%	0.042	19%	0.185	C	C	.	.	H	α-helix	trans	-63.4	-38.3	176.8	-67.2	178.8	0	0	0	112	L131 V132 V138 H139 F202 F205 L261 T264	L131-L135 HydrophobicContact CD1-CG 4.43Å; L131-L135 HydrophobicContact CG-CD1 4.42Å; L131-L135 VanDerWaalsContact O-CG 3.31Å; L131-L135 WeakPolarHBondContact O-CG 3.41Å; L131-L135 PolarHBondContact O-N 3.18Å; V132-L135 PolarHBondContact O-N 2.91Å; L135-V138 PolarHBondContact O-N 3.16Å; L135-H139 WeakPolarHBondContact O-CB 3.31Å; L135-H139 PolarHBondContact O-N 3.44Å; L135-F202 HydrophobicContact CD1-CD2 4.36Å; L135-F202 HydrophobicContact CD2-CD2 4.01Å; L135-F202 HydrophobicContact CD2-CE2 3.88Å; L135-F205 HydrophobicContact CB-CD2 4.44Å; L135-F205 HydrophobicContact CB-CE1 4.46Å; L135-F205 HydrophobicContact CB-CE2 4.04Å; L135-F205 HydrophobicContact CB-CZ 4.05Å; L135-F205 HydrophobicContact CD1-CG 4.44Å; L135-F205 HydrophobicContact CD2-CD1 3.87Å; L135-F205 HydrophobicContact CD2-CE1 3.8Å; L135-F205 HydrophobicContact CD2-CG 4.38Å; L135-F205 HydrophobicContact CD2-CZ 4.25Å; L135-F205 WeakPolarHBondContact O-CZ 3.33Å; L135-L261 HydrophobicContact CB-CD2 3.55Å; L135-L261 HydrophobicContact CD1-CD2 3.8Å; L135-L261 HydrophobicContact CG-CD2 4.35Å; L135-T264 HydrophobicContact CD1-CG2 4.02Å
136	L	97.3	Very high	95.3	Very high	3 Å²	3	35.1 Å²	35.1	2%	0.016	18%	0.182	C	C	.	.	H	α-helix	trans	-63.4	-40	171.7	-79.7	179.4	0	0	0	112.2	V132 L133 L134 H139 S140 L173 V177 L261 W272	V132-L136 WeakPolarHBondContact O-CB 3.42Å; V132-L136 WeakPolarHBondContact O-CG 3.47Å; V132-L136 PolarHBondContact O-N 3.16Å; L133-L136 PolarHBondContact O-N 3.42Å; L134-L136 VanDerWaalsContact C-N 3.34Å; L134-L136 PolarHBondContact O-N 3.26Å; L136-H139 PolarHBondContact O-N 2.99Å; L136-S140 VanDerWaalsContact O-CB 3.3Å; L136-S140 WeakPolarHBondContact O-CB 3.3Å; L136-S140 PolarHBondContact O-N 2.91Å; L136-S140 PolarHBondContact O-OG 2.94Å; L136-L173 HydrophobicContact CD1-CD2 4.41Å; L136-L173 HydrophobicContact CD1-CG 4.23Å; L136-L173 HydrophobicContact CD2-CD2 3.94Å; L136-V177 HydrophobicContact CD1-CG2 3.53Å; L136-L261 HydrophobicContact CD2-CD1 3.49Å; L136-L261 VanDerWaalsContact CD2-CD1 3.49Å; L136-L261 HydrophobicContact CG-CD1 3.94Å; L136-W272 HydrophobicContact CD1-CH2 4.33Å
137	C	97.6	Very high	95.7	Very high	14 Å²	14	30.8 Å²	30.8	10%	0.095	16%	0.163	C	C	.	.	H	α-helix	trans	-62.3	-45.2	173.9	-173.2	0	0	0	0	111.2	N82 I83 L86 L133 L134 S140 L141	N82-C137 HydrophobicContact CB-CB 4.18Å; I83-C137 VanDerWaalsContact CG1-SG 3.55Å; L86-C137 HydrophobicContact CD1-CB 3.95Å; L133-C137 WeakPolarHBondContact O-CB 3.41Å; L133-C137 PolarHBondContact O-N 2.88Å; L134-C137 WeakPolarHBondContact O-CB 3.42Å; L134-C137 PolarHBondContact O-N 3.43Å; L134-C137 VanDerWaalsContact O-N 3.15Å; C137-S140 WeakPolarHBondContact CA-OG 3.08Å; C137-S140 PolarHBondContact O-OG 2.93Å; C137-L141 WeakPolarHBondContact O-CB 3.42Å; C137-L141 PolarHBondContact O-N 2.71Å
138	V	98.3	Very high	96	Very high	75 Å²	75	28 Å²	28	46%	0.455	15%	0.148	S	C	.	.	H	α-helix	trans	-63.5	-45.2	176.8	170.7	0	0	0	0	111.3	L134 L135 R142 F205	L134-V138 WeakPolarHBondContact O-CG2 3.31Å; L134-V138 PolarHBondContact O-N 2.49Å; L135-V138 PolarHBondContact O-N 3.16Å; V138-R142 WeakPolarHBondContact O-CB 3.4Å; V138-R142 PolarHBondContact O-N 2.84Å; V138-F205 HydrophobicContact CG1-CE1 4.48Å
139	H	98.3	Very high	96.2	Very high	2 Å²	2	34.8 Å²	34.8	1%	0.009	18%	0.177	C	C	.	.	H	α-helix	trans	-58.7	-53.8	176.2	176.6	56.3	0	0	0	111.2	L135 L136 L141 R142 R143 F205 E254	L135-H139 WeakPolarHBondContact O-CB 3.31Å; L135-H139 PolarHBondContact O-N 3.44Å; L136-H139 PolarHBondContact O-N 2.99Å; H139-L141 PolarHBondContact O-N 2.99Å; H139-R142 PolarHBondContact CE1-NH2 3.2Å; H139-R142 PolarHBondContact ND1-NH2 3.22Å; H139-R142 PolarHBondContact O-N 3.22Å; H139-R143 WeakPolarHBondContact O-CB 3.4Å; H139-R143 VanDerWaalsContact O-CG 3.27Å; H139-R143 WeakPolarHBondContact O-CG 3.37Å; H139-R143 PolarHBondContact O-N 3.13Å; H139-F205 HydrophobicContact CB-CE2 4.14Å; H139-F205 HydrophobicContact CB-CZ 4Å; H139-E254 IonicContact CE1-OE1 3.88Å; H139-E254 IonicContact CE1-OE2 3.49Å; H139-E254 PolarHBondContact CE1-OE2 3.17Å; H139-E254 IonicContact NE2-OE1 2.75Å; H139-E254 PolarHBondContact NE2-OE1 3.03Å; H139-E254 VanDerWaalsContact NE2-OE1 3.12Å; H139-E254 IonicContact NE2-OE2 2.7Å; H139-E254 PolarHBondContact NE2-OE2 3.08Å
140	S	97.6	Very high	96.2	Very high	1 Å²	1	36.1 Å²	36.1	1%	0.007	19%	0.185	C	C	.	.	H	α-helix	trans	-63.5	-39.1	-178.5	54.9	0	0	0	0	112.5	S78 V79 L136 C137 R143 L144	S78-S140 VanDerWaalsContact OG-CB 3.3Å; S78-S140 WeakPolarHBondContact OG-CB 3.13Å; V79-S140 WeakPolarHBondContact CG2-OG 3.43Å; L136-S140 VanDerWaalsContact O-CB 3.3Å; L136-S140 WeakPolarHBondContact O-CB 3.3Å; L136-S140 PolarHBondContact O-N 2.91Å; L136-S140 PolarHBondContact O-OG 2.94Å; C137-S140 WeakPolarHBondContact CA-OG 3.08Å; C137-S140 PolarHBondContact O-OG 2.93Å; S140-R143 PolarHBondContact O-N 3.28Å; S140-L144 WeakPolarHBondContact O-CB 3.36Å; S140-L144 PolarHBondContact O-N 3.14Å
141	L	98.2	Very high	96	Very high	76 Å²	76	36.7 Å²	36.7	40%	0.398	19%	0.189	S	C	.	.	H	α-helix	trans	-63.7	-47.8	175.2	179	60.6	0	0	0	111.3	V79 C137 H139 R143 L144 L145	V79-L141 HydrophobicContact CG2-CB 4.02Å; C137-L141 WeakPolarHBondContact O-CB 3.42Å; C137-L141 PolarHBondContact O-N 2.71Å; H139-L141 PolarHBondContact O-N 2.99Å; L141-R143 VanDerWaalsContact C-N 3.31Å; L141-R143 PolarHBondContact O-N 3.35Å; L141-L144 WeakPolarHBondContact O-CB 3.48Å; L141-L144 PolarHBondContact O-N 3.31Å; L141-L145 HydrophobicContact CD1-CD1 4.42Å; L141-L145 HydrophobicContact CD1-CG 4.29Å; L141-L145 HydrophobicContact CG-CD1 4.26Å; L141-L145 VanDerWaalsContact O-CG 3.31Å; L141-L145 WeakPolarHBondContact O-CG 3.38Å; L141-L145 PolarHBondContact O-N 3.47Å
142	R	97.9	Very high	95.6	Very high	42 Å²	42	35 Å²	35	16%	0.158	18%	0.181	C	C	.	.	H	α-helix	trans	-56.4	-47.7	175.3	176.5	-175.4	61.2	101.3	-5.2	110.9	V138 H139 L144 L145 E146 S209	V138-R142 WeakPolarHBondContact O-CB 3.4Å; V138-R142 PolarHBondContact O-N 2.84Å; H139-R142 PolarHBondContact CE1-NH2 3.2Å; H139-R142 PolarHBondContact ND1-NH2 3.22Å; H139-R142 PolarHBondContact O-N 3.22Å; R142-L144 VanDerWaalsContact C-N 3.32Å; R142-L144 PolarHBondContact O-N 3.06Å; R142-L145 PolarHBondContact O-N 3.11Å; R142-E146 HydrophobicContact CG-CG 4.42Å; R142-E146 WeakPolarHBondContact CG-OE1 3.23Å; R142-E146 IonicContact CZ-OE1 2.72Å; R142-E146 IonicContact NH1-OE1 3.72Å; R142-E146 PolarHBondContact NH1-OE1 2.84Å; R142-E146 IonicContact NH1-OE2 2.78Å; R142-E146 WeakPolarHBondContact O-CB 3.2Å; R142-E146 VanDerWaalsContact O-CG 3.31Å; R142-E146 WeakPolarHBondContact O-CG 3.34Å; R142-E146 PolarHBondContact O-N 3.13Å; R142-S209 PolarHBondContact NH1-O 3.27Å
143	R	97.3	Very high	95	Very high	15 Å²	15	37.5 Å²	37.5	6%	0.057	19%	0.192	C	C	.	.	H	α-helix	trans	-63.2	-37.1	178.8	-69.6	-63.3	-59.8	159.3	-8.1	112.6	Y75 H139 S140 L141 E146 C147 M216	Y75-R143 HydrophobicContact CD1-CB 3.41Å; Y75-R143 VanDerWaalsContact CD1-CB 3.41Å; Y75-R143 HydrophobicContact CD1-CG 4.23Å; Y75-R143 HydrophobicContact CD2-CB 4.05Å; Y75-R143 HydrophobicContact CE1-CB 3.35Å; Y75-R143 HydrophobicContact CE1-CG 3.76Å; Y75-R143 HydrophobicContact CE2-CB 3.99Å; Y75-R143 HydrophobicContact CG-CB 3.76Å; Y75-R143 PolarHBondContact OH-NE 3.36Å; Y75-R143 VanDerWaalsContact OH-NE 3.08Å; Y75-R143 PolarHBondContact OH-NH2 2.94Å; Y75-R143 VanDerWaalsContact OH-NH2 3.07Å; H139-R143 WeakPolarHBondContact O-CB 3.4Å; H139-R143 VanDerWaalsContact O-CG 3.27Å; H139-R143 WeakPolarHBondContact O-CG 3.37Å; H139-R143 PolarHBondContact O-N 3.13Å; S140-R143 PolarHBondContact O-N 3.28Å; L141-R143 VanDerWaalsContact C-N 3.31Å; L141-R143 PolarHBondContact O-N 3.35Å; R143-E146 WeakPolarHBondContact CD-OE2 3.28Å; R143-E146 IonicContact CZ-OE2 3.86Å; R143-E146 IonicContact NE-OE2 3.47Å; R143-E146 IonicContact NH1-OE2 3.62Å; R143-E146 PolarHBondContact NH1-OE2 2.97Å; R143-E146 PolarHBondContact O-N 3.1Å; R143-C147 PolarHBondContact O-N 3.07Å; R143-C147 PolarHBondContact O-SG 2.94Å; R143-M216 VanDerWaalsContact NH1-CG 3.3Å; R143-M216 PolarHBondContact NH1-SD 3.34Å; R143-M216 VanDerWaalsContact NH1-SD 3.42Å
144	L	97.5	Very high	94.1	Very high	22 Å²	22	38.3 Å²	38.3	12%	0.115	20%	0.198	C	C	.	.	H	α-helix	trans	-61.5	-50.8	172.8	178.5	58.6	0	0	0	110.9	W72 A76 V79 S140 L141 R142 E146 C147 L148	W72-L144 HydrophobicContact CB-CD1 4.11Å; W72-L144 HydrophobicContact CE3-CD1 4.16Å; A76-L144 HydrophobicContact CB-CD1 4.18Å; A76-L144 HydrophobicContact CB-CD2 4.45Å; V79-L144 HydrophobicContact CG2-CD2 4.26Å; S140-L144 WeakPolarHBondContact O-CB 3.36Å; S140-L144 PolarHBondContact O-N 3.14Å; L141-L144 WeakPolarHBondContact O-CB 3.48Å; L141-L144 PolarHBondContact O-N 3.31Å; R142-L144 VanDerWaalsContact C-N 3.32Å; R142-L144 PolarHBondContact O-N 3.06Å; L144-E146 VanDerWaalsContact C-N 3.32Å; L144-E146 PolarHBondContact O-N 2.77Å; L144-C147 WeakPolarHBondContact O-CB 3.19Å; L144-C147 PolarHBondContact O-N 2.95Å; L144-L148 HydrophobicContact CD1-CD1 3.97Å; L144-L148 HydrophobicContact CD1-CG 4.2Å; L144-L148 HydrophobicContact CG-CD1 4.04Å; L144-L148 WeakPolarHBondContact O-CG 3.38Å; L144-L148 PolarHBondContact O-N 3.3Å
145	L	97.3	Very high	93.2	Very high	80 Å²	80	39.7 Å²	39.7	42%	0.419	21%	0.206	S	C	.	.	H	α-helix	trans	-61.1	-41.5	177.9	-64.1	174.9	0	0	0	111.6	L141 R142 C147 L148 F149	L141-L145 HydrophobicContact CD1-CD1 4.42Å; L141-L145 HydrophobicContact CD1-CG 4.29Å; L141-L145 HydrophobicContact CG-CD1 4.26Å; L141-L145 VanDerWaalsContact O-CG 3.31Å; L141-L145 WeakPolarHBondContact O-CG 3.38Å; L141-L145 PolarHBondContact O-N 3.47Å; R142-L145 PolarHBondContact O-N 3.11Å; L145-C147 VanDerWaalsContact C-N 3.29Å; L145-C147 PolarHBondContact O-N 2.56Å; L145-L148 PolarHBondContact O-N 2.92Å; L145-F149 HydrophobicContact CB-CD2 4.25Å; L145-F149 HydrophobicContact CD2-CD2 4.04Å; L145-F149 HydrophobicContact CD2-CE2 3.65Å; L145-F149 WeakPolarHBondContact O-CB 3.37Å; L145-F149 WeakPolarHBondContact O-CD2 3.32Å; L145-F149 PolarHBondContact O-N 3.24Å
146	E	95.9	Very high	92.3	Very high	3 Å²	3	39.5 Å²	39.5	1%	0.014	21%	0.206	C	C	.	.	I	π-helix	trans	-61.9	-36.1	173.9	-74.7	171.1	-173.6	0	0	112.2	R142 R143 L144 V150 S151 H213	R142-E146 HydrophobicContact CG-CG 4.42Å; R142-E146 WeakPolarHBondContact CG-OE1 3.23Å; R142-E146 IonicContact CZ-OE1 2.72Å; R142-E146 IonicContact NH1-OE1 3.72Å; R142-E146 PolarHBondContact NH1-OE1 2.84Å; R142-E146 IonicContact NH1-OE2 2.78Å; R142-E146 WeakPolarHBondContact O-CB 3.2Å; R142-E146 VanDerWaalsContact O-CG 3.31Å; R142-E146 WeakPolarHBondContact O-CG 3.34Å; R142-E146 PolarHBondContact O-N 3.13Å; R143-E146 WeakPolarHBondContact CD-OE2 3.28Å; R143-E146 IonicContact CZ-OE2 3.86Å; R143-E146 IonicContact NE-OE2 3.47Å; R143-E146 IonicContact NH1-OE2 3.62Å; R143-E146 PolarHBondContact NH1-OE2 2.97Å; R143-E146 PolarHBondContact O-N 3.1Å; L144-E146 VanDerWaalsContact C-N 3.32Å; L144-E146 PolarHBondContact O-N 2.77Å; E146-V150 HydrophobicContact CB-CB 4.46Å; E146-V150 HydrophobicContact CG-CG2 4.45Å; E146-V150 CarbonylContact O-C 3.56Å; E146-V150 WeakPolarHBondContact O-CA 3.43Å; E146-V150 WeakPolarHBondContact O-CB 3.47Å; E146-V150 PolarHBondContact O-N 3.31Å; E146-V150 VanDerWaalsContact O-N 3.13Å; E146-S151 WeakPolarHBondContact O-CB 3.4Å; E146-S151 PolarHBondContact O-N 3.2Å; E146-S151 PolarHBondContact O-OG 3.13Å; E146-H213 WeakPolarHBondContact OE1-CB 3.37Å; E146-H213 IonicContact OE1-CE1 3.26Å; E146-H213 IonicContact OE1-CG 3.21Å; E146-H213 IonicContact OE1-ND1 2.63Å; E146-H213 PolarHBondContact OE1-ND1 3.44Å
147	C	94.3	Very high	91.6	Very high	6 Å²	6	40.4 Å²	40.4	4%	0.041	21%	0.213	C	C	.	.	I	π-helix	trans	-69	-41.6	175.1	-69.6	0	0	0	0	111.8	W72 Y75 R143 L144 L145 F153	W72-C147 HydrophobicContact CB-CB 3.75Å; Y75-C147 VanDerWaalsContact CE2-SG 3.57Å; R143-C147 PolarHBondContact O-N 3.07Å; R143-C147 PolarHBondContact O-SG 2.94Å; L144-C147 WeakPolarHBondContact O-CB 3.19Å; L144-C147 PolarHBondContact O-N 2.95Å; L145-C147 VanDerWaalsContact C-N 3.29Å; L145-C147 PolarHBondContact O-N 2.56Å; C147-F153 HydrophobicContact CB-CE2 4.32Å; C147-F153 HydrophobicContact CB-CZ 4.12Å; C147-F153 WeakPolarHBondContact O-CE2 3.48Å
148	L	93.8	Very high	91	Very high	87 Å²	87	40 Å²	40	46%	0.455	21%	0.21	S	C	.	.	I	π-helix	trans	-76.3	-38.3	-175.8	-65.2	174.3	0	0	0	112.9	W72 L144 L145	W72-L148 HydrophobicContact CB-CD2 4.23Å; W72-L148 HydrophobicContact CD2-CD2 4.26Å; W72-L148 HydrophobicContact CG-CD2 4.1Å; L144-L148 HydrophobicContact CD1-CD1 3.97Å; L144-L148 HydrophobicContact CD1-CG 4.2Å; L144-L148 HydrophobicContact CG-CD1 4.04Å; L144-L148 WeakPolarHBondContact O-CG 3.38Å; L144-L148 PolarHBondContact O-N 3.3Å; L145-L148 PolarHBondContact O-N 2.92Å
149	F	93.2	Very high	90.5	Very high	149 Å²	149	37.5 Å²	37.5	65%	0.654	19%	0.194	S	C	*	.	I	π-helix	trans	-115.6	-29.6	-167.6	-57.3	-64.7	0	0	0	114.4	L145	L145-F149 HydrophobicContact CB-CD2 4.25Å; L145-F149 HydrophobicContact CD2-CD2 4.04Å; L145-F149 HydrophobicContact CD2-CE2 3.65Å; L145-F149 WeakPolarHBondContact O-CB 3.37Å; L145-F149 WeakPolarHBondContact O-CD2 3.32Å; L145-F149 PolarHBondContact O-N 3.24Å
150	V	91.7	Very high	89.9	Confident	29 Å²	29	40.5 Å²	40.5	18%	0.176	21%	0.209	C	C	.	.	I	π-helix	trans	-97.7	-51.6	-175	-179.1	0	0	0	0	111.1	E146 V217 A220 K224	E146-V150 HydrophobicContact CB-CB 4.46Å; E146-V150 HydrophobicContact CG-CG2 4.45Å; E146-V150 CarbonylContact O-C 3.56Å; E146-V150 WeakPolarHBondContact O-CA 3.43Å; E146-V150 WeakPolarHBondContact O-CB 3.47Å; E146-V150 PolarHBondContact O-N 3.31Å; E146-V150 VanDerWaalsContact O-N 3.13Å; V150-V217 HydrophobicContact CG1-CG2 4.02Å; V150-A220 HydrophobicContact CG1-CB 4.01Å; V150-A220 WeakPolarHBondContact O-CB 3.3Å; V150-K224 PolarHBondContact O-NZ 2.91Å; V150-K224 VanDerWaalsContact O-NZ 3.1Å
151	S	89.1	Confident	89.4	Confident	21 Å²	21	44.4 Å²	44.4	15%	0.147	23%	0.233	C	C	.	.			trans	-70.4	132.1	-168.7	-60.2	0	0	0	0	111.7	E146 M216	E146-S151 WeakPolarHBondContact O-CB 3.4Å; E146-S151 PolarHBondContact O-N 3.2Å; E146-S151 PolarHBondContact O-OG 3.13Å; S151-M216 VanDerWaalsContact OG-CE 3.3Å; S151-M216 WeakPolarHBondContact OG-CE 3.48Å
152	V	86.6	Confident	88.9	Confident	21 Å²	21	42.6 Å²	42.6	13%	0.127	22%	0.222	C	C	.	.			trans	-101.2	110	169.9	-178.4	0	0	0	0	107.1	R223 K224 V230 L233	V152-R223 HydrophobicContact CB-CB 4.1Å; V152-R223 HydrophobicContact CG1-CB 4.09Å; V152-R223 HydrophobicContact CG2-CB 4.29Å; V152-R223 PolarHBondContact O-NH1 3.31Å; V152-K224 HydrophobicContact CG2-CD 4.29Å; V152-K224 VanDerWaalsContact CG2-CE 3.41Å; V152-K224 HydrophobicContact CG2-CG 3.99Å; V152-V230 HydrophobicContact CG1-CG1 3.83Å; V152-V230 HydrophobicContact CG1-CG2 3.82Å; V152-V230 HydrophobicContact CG2-CG2 3.9Å; V152-L233 HydrophobicContact CG1-CD2 3.9Å
153	F	82.3	Confident	88.6	Confident	53 Å²	53	41.9 Å²	41.9	23%	0.232	22%	0.22	C	C	.	.			trans	-85.5	138.6	176.9	-62.7	-79.3	0	0	0	110.7	K68 R69 F71 C147	K68-F153 HydrophobicContact CG-CD1 4.24Å; R69-F153 HydrophobicContact CB-CB 4.21Å; F71-F153 HydrophobicContact CB-CE1 3.98Å; F71-F153 HydrophobicContact CB-CZ 4.19Å; C147-F153 HydrophobicContact CB-CE2 4.32Å; C147-F153 HydrophobicContact CB-CZ 4.12Å; C147-F153 WeakPolarHBondContact O-CE2 3.48Å
154	S	77.8	Confident	88.5	Confident	16 Å²	16	46 Å²	46	11%	0.112	24%	0.242	C	C	.	.			trans	-94.5	175.9	169.2	57	0	0	0	0	109.7	G156	S154-G156 PolarHBondContact O-N 2.97Å
155	D	77.9	Confident	88.2	Confident	111 Å²	111	48.5 Å²	48.5	59%	0.594	25%	0.252	S	S	*	.	S	Bend	trans	-72.6	41.3	174.5	-62.2	-43.8	0	0	0	113.8	Q53 R69	Q53-D155 PolarHBondContact NE2-O 3.39Å; R69-D155 IonicContact CZ-OD1 3.81Å; R69-D155 IonicContact NH2-OD1 3.19Å; R69-D155 PolarHBondContact NH2-OD1 3.01Å
156	G	78.5	Confident	88.1	Confident	4 Å²	4	45.2 Å²	45.2	4%	0.041	24%	0.238	C	C	.	.			trans	-74.6	154.1	168.3	0	0	0	0	0	110.8	K68 S154	K68-G156 WeakPolarHBondContact CB-O 3.42Å; K68-G156 PolarHBondContact N-O 3.33Å; S154-G156 PolarHBondContact O-N 2.97Å
157	A	83.6	Confident	88	Confident	21 Å²	21	46.6 Å²	46.6	17%	0.174	25%	0.246	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-119.4	156	173.3	0	0	0	0	0	111.7	G49 D65 V66	G49-A157 PolarHBondContact N-O 2.85Å; D65-A157 HydrophobicContact CB-CB 3.64Å; V66-A157 CarbonylContact O-C 3.56Å; V66-A157 WeakPolarHBondContact O-CA 3.46Å
158	M	84.7	Confident	88.1	Confident	6 Å²	6	48 Å²	48	3%	0.03	26%	0.26	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-121	154.1	167	64.6	-178.7	65.6	0	0	108.9	V66 K68 F71 F74 Y163	V66-M158 HydrophobicContact CB-CG 4Å; V66-M158 HydrophobicContact CG1-CG 4.47Å; V66-M158 PolarHBondContact N-O 3.4Å; V66-M158 PolarHBondContact O-N 3.48Å; K68-M158 HydrophobicContact CG-CE 4.39Å; F71-M158 HydrophobicContact CD2-CE 3.79Å; F74-M158 HydrophobicContact CE2-CE 4.15Å; F74-M158 HydrophobicContact CE2-SD 4.05Å; F74-M158 HydrophobicContact CZ-CE 4.39Å; F74-M158 HydrophobicContact CZ-SD 3.71Å; M158-Y163 HydrophobicContact SD-CD2 3.9Å; M158-Y163 HydrophobicContact SD-CG 4.45Å
159	H	86.2	Confident	88.2	Confident	23 Å²	23	44.9 Å²	44.9	11%	0.106	24%	0.243	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-72.2	146.3	177.9	-166.5	-95.1	0	0	0	111.2	D44 F64 V161 Q162 Y163	D44-H159 IonicContact OD2-CD2 3.4Å; D44-H159 PolarHBondContact OD2-CD2 3.04Å; F64-H159 CarbonylContact O-C 3.58Å; H159-V161 VanDerWaalsContact C-N 3.26Å; H159-V161 WeakPolarHBondContact ND1-CB 3.13Å; H159-V161 PolarHBondContact ND1-N 3.09Å; H159-V161 PolarHBondContact O-N 3.29Å; H159-Q162 HydrophobicContact CB-CG 4.11Å; H159-Q162 WeakPolarHBondContact O-CB 3.42Å; H159-Q162 PolarHBondContact O-N 3.15Å; H159-Y163 PolarHBondContact O-N 3.48Å
160	L	86.6	Confident	88.4	Confident	65 Å²	65	38.6 Å²	38.6	34%	0.34	22%	0.215	S	C	.	.	H	α-helix	trans	-55.4	-40.2	179.7	178.6	62.3	0	0	0	112.6	F64 V66 Q162 Y163 L164	F64-L160 HydrophobicContact CB-CB 4.25Å; F64-L160 HydrophobicContact CD1-CD2 4.19Å; F64-L160 WeakPolarHBondContact O-CB 3.01Å; F64-L160 PolarHBondContact O-N 3.19Å; V66-L160 HydrophobicContact CG2-CB 4.08Å; V66-L160 HydrophobicContact CG2-CD1 3.78Å; L160-Q162 VanDerWaalsContact C-N 3.34Å; L160-Q162 PolarHBondContact O-N 2.85Å; L160-Y163 HydrophobicContact CD1-CD1 4.31Å; L160-Y163 WeakPolarHBondContact O-CB 3.19Å; L160-Y163 PolarHBondContact O-N 3.25Å; L160-Y163 VanDerWaalsContact O-N 3.12Å; L160-L164 HydrophobicContact CD1-CD1 4.47Å; L160-L164 HydrophobicContact CD1-CG 4.21Å; L160-L164 HydrophobicContact CG-CD1 4.31Å; L160-L164 HydrophobicContact CG-CG 4.44Å; L160-L164 WeakPolarHBondContact O-CG 3.5Å; L160-L164 PolarHBondContact O-N 2.99Å
161	V	87.3	Confident	88.6	Confident	83 Å²	83	39.8 Å²	39.8	50%	0.503	22%	0.22	S	C	.	.	H	α-helix	trans	-60.7	-42.7	175.9	176.8	0	0	0	0	111.4	L45 H159 Y163 F165	L45-V161 HydrophobicContact CD1-CB 4.36Å; L45-V161 HydrophobicContact CD1-CG1 4.3Å; H159-V161 VanDerWaalsContact C-N 3.26Å; H159-V161 WeakPolarHBondContact ND1-CB 3.13Å; H159-V161 PolarHBondContact ND1-N 3.09Å; H159-V161 PolarHBondContact O-N 3.29Å; V161-Y163 VanDerWaalsContact C-N 3.28Å; V161-Y163 PolarHBondContact O-N 2.93Å; V161-F165 WeakPolarHBondContact O-CB 3.31Å; V161-F165 PolarHBondContact O-N 3.1Å
162	Q	88.4	Confident	89	Confident	38 Å²	38	41.4 Å²	41.4	18%	0.178	23%	0.229	C	C	.	.	H	α-helix	trans	-63.9	-38.2	175.5	-64.4	169.1	-28.2	0	0	110.8	L45 R47 H159 L160 G166	L45-Q162 PolarHBondContact O-NE2 3.4Å; R47-Q162 PolarHBondContact O-NE2 3.47Å; R47-Q162 VanDerWaalsContact O-NE2 3.14Å; H159-Q162 HydrophobicContact CB-CG 4.11Å; H159-Q162 WeakPolarHBondContact O-CB 3.42Å; H159-Q162 PolarHBondContact O-N 3.15Å; L160-Q162 VanDerWaalsContact C-N 3.34Å; L160-Q162 PolarHBondContact O-N 2.85Å; Q162-G166 PolarHBondContact O-N 3.02Å
163	Y	91.1	Very high	89.5	Confident	27 Å²	27	40.5 Å²	40.5	11%	0.106	22%	0.223	C	C	.	.	H	α-helix	trans	-64.2	-52.5	178.1	177.8	-100.3	0	0	0	111.7	V66 W70 H73 F74 M158 H159 L160 V161 F165 G166 L167	V66-Y163 HydrophobicContact CB-CG 4.48Å; V66-Y163 HydrophobicContact CG1-CD1 4.47Å; V66-Y163 HydrophobicContact CG1-CD2 3.93Å; V66-Y163 HydrophobicContact CG1-CE2 4.35Å; V66-Y163 HydrophobicContact CG1-CG 4.01Å; V66-Y163 HydrophobicContact CG2-CG 4.36Å; W70-Y163 HydrophobicContact CB-CE2 4.19Å; W70-Y163 HydrophobicContact CE3-CE2 4.38Å; H73-Y163 HydrophobicContact CB-CE2 4.35Å; H73-Y163 AromaticContact ND1-CE2 3.9Å; H73-Y163 AromaticContact ND1-CZ 3.74Å; H73-Y163 PolarHBondContact ND1-OH 3.49Å; F74-Y163 HydrophobicContact CD1-CE2 4.49Å; F74-Y163 AromaticContact CE1-CD2 3.41Å; F74-Y163 HydrophobicContact CE1-CD2 3.41Å; F74-Y163 VanDerWaalsContact CE1-CD2 3.41Å; F74-Y163 AromaticContact CE1-CE2 3.67Å; F74-Y163 HydrophobicContact CE1-CE2 3.67Å; F74-Y163 HydrophobicContact CE1-CG 4.13Å; F74-Y163 WeakPolarHBondContact CE1-O 3.24Å; F74-Y163 AromaticContact CZ-CD2 3.46Å; F74-Y163 HydrophobicContact CZ-CD2 3.46Å; F74-Y163 VanDerWaalsContact CZ-CD2 3.46Å; F74-Y163 HydrophobicContact CZ-CE2 4.05Å; F74-Y163 HydrophobicContact CZ-CG 4.26Å; M158-Y163 HydrophobicContact SD-CD2 3.9Å; M158-Y163 HydrophobicContact SD-CG 4.45Å; H159-Y163 PolarHBondContact O-N 3.48Å; L160-Y163 HydrophobicContact CD1-CD1 4.31Å; L160-Y163 WeakPolarHBondContact O-CB 3.19Å; L160-Y163 PolarHBondContact O-N 3.25Å; L160-Y163 VanDerWaalsContact O-N 3.12Å; V161-Y163 VanDerWaalsContact C-N 3.28Å; V161-Y163 PolarHBondContact O-N 2.93Å; Y163-F165 VanDerWaalsContact C-N 3.32Å; Y163-F165 PolarHBondContact O-N 3.35Å; Y163-G166 PolarHBondContact O-N 3.15Å; Y163-G166 VanDerWaalsContact O-N 3.13Å; Y163-L167 HydrophobicContact CD1-CD1 4.15Å; Y163-L167 HydrophobicContact CE1-CD1 3.59Å; Y163-L167 HydrophobicContact CE1-CG 4.31Å; Y163-L167 HydrophobicContact CE2-CD2 4.42Å; Y163-L167 WeakPolarHBondContact O-CG 3.31Å; Y163-L167 PolarHBondContact O-N 3.29Å; Y163-L167 VanDerWaalsContact O-N 3.07Å
164	L	94	Very high	90.2	Very high	101 Å²	101	38 Å²	38	53%	0.529	21%	0.212	S	C	.	.	H	α-helix	trans	-61.3	-41.2	177.2	-65.2	178.9	0	0	0	112.1	L160 G166 L167 G168	L160-L164 HydrophobicContact CD1-CD1 4.47Å; L160-L164 HydrophobicContact CD1-CG 4.21Å; L160-L164 HydrophobicContact CG-CD1 4.31Å; L160-L164 HydrophobicContact CG-CG 4.44Å; L160-L164 WeakPolarHBondContact O-CG 3.5Å; L160-L164 PolarHBondContact O-N 2.99Å; L164-G166 VanDerWaalsContact C-N 3.32Å; L164-G166 PolarHBondContact O-N 2.66Å; L164-L167 HydrophobicContact CD2-CD1 4.4Å; L164-L167 PolarHBondContact O-N 3.22Å; L164-G168 PolarHBondContact O-N 2.84Å
165	F	93.1	Very high	91.1	Very high	74 Å²	74	37.8 Å²	37.8	33%	0.325	21%	0.21	S	C	.	.	H	α-helix	trans	-58.6	-43.9	174	177.5	-94	0	0	0	111.7	L12 F16 V161 Y163 L167 G168 Y169 Y278	L12-F165 HydrophobicContact CD1-CE2 4.24Å; L12-F165 HydrophobicContact CD1-CZ 4.25Å; L12-F165 HydrophobicContact CD2-CE2 3.65Å; L12-F165 HydrophobicContact CD2-CZ 3.98Å; F16-F165 HydrophobicContact CE2-CZ 4.5Å; V161-F165 WeakPolarHBondContact O-CB 3.31Å; V161-F165 PolarHBondContact O-N 3.1Å; Y163-F165 VanDerWaalsContact C-N 3.32Å; Y163-F165 PolarHBondContact O-N 3.35Å; F165-L167 PolarHBondContact O-N 3.07Å; F165-G168 PolarHBondContact O-N 3.42Å; F165-Y169 VanDerWaalsContact O-CB 3.29Å; F165-Y169 WeakPolarHBondContact O-CB 3.5Å; F165-Y169 PolarHBondContact O-N 3.36Å; F165-Y278 WeakPolarHBondContact CE1-OH 3.48Å; F165-Y278 HydrophobicContact CZ-CE2 4.23Å
166	G	93.3	Very high	92	Very high	12 Å²	12	32.5 Å²	32.5	12%	0.124	18%	0.182	C	C	.	.	H	α-helix	trans	-62.5	-38.1	176.9	0	0	0	0	0	113.7	Q162 Y163 L164 Y170	Q162-G166 PolarHBondContact O-N 3.02Å; Y163-G166 PolarHBondContact O-N 3.15Å; Y163-G166 VanDerWaalsContact O-N 3.13Å; L164-G166 VanDerWaalsContact C-N 3.32Å; L164-G166 PolarHBondContact O-N 2.66Å; G166-Y170 VanDerWaalsContact O-CD2 3.31Å; G166-Y170 WeakPolarHBondContact O-CD2 3.49Å
167	L	94.9	Very high	92.7	Very high	32 Å²	32	32.3 Å²	32.3	17%	0.168	18%	0.18	C	C	.	.	H	α-helix	trans	-66.3	-48.6	174.7	-59.3	172.9	0	0	0	111	H73 F74 I77 Y163 L164 F165 Y169 Y170	H73-L167 HydrophobicContact CB-CD2 4.26Å; F74-L167 HydrophobicContact CD1-CD2 3.49Å; F74-L167 VanDerWaalsContact CD1-CD2 3.49Å; F74-L167 HydrophobicContact CD1-CG 4Å; F74-L167 HydrophobicContact CE1-CD2 3.86Å; F74-L167 HydrophobicContact CE1-CG 4Å; I77-L167 HydrophobicContact CD1-CB 4.2Å; I77-L167 HydrophobicContact CD1-CD1 4.48Å; I77-L167 HydrophobicContact CD1-CD2 3.41Å; I77-L167 VanDerWaalsContact CD1-CD2 3.41Å; I77-L167 HydrophobicContact CD1-CG 4.2Å; I77-L167 HydrophobicContact CG1-CD2 4.37Å; Y163-L167 HydrophobicContact CD1-CD1 4.15Å; Y163-L167 HydrophobicContact CE1-CD1 3.59Å; Y163-L167 HydrophobicContact CE1-CG 4.31Å; Y163-L167 HydrophobicContact CE2-CD2 4.42Å; Y163-L167 WeakPolarHBondContact O-CG 3.31Å; Y163-L167 PolarHBondContact O-N 3.29Å; Y163-L167 VanDerWaalsContact O-N 3.07Å; L164-L167 HydrophobicContact CD2-CD1 4.4Å; L164-L167 PolarHBondContact O-N 3.22Å; F165-L167 PolarHBondContact O-N 3.07Å; L167-Y169 VanDerWaalsContact C-N 3.31Å; L167-Y169 PolarHBondContact O-N 3.08Å; L167-Y170 PolarHBondContact O-N 3.33Å
168	G	96.6	Very high	93.2	Very high	34 Å²	34	31.6 Å²	31.6	35%	0.351	17%	0.173	S	C	.	.	H	α-helix	trans	-63.1	-36.6	179.2	0	0	0	0	0	112.9	L164 F165 Y170 I171 V172	L164-G168 PolarHBondContact O-N 2.84Å; F165-G168 PolarHBondContact O-N 3.42Å; G168-Y170 VanDerWaalsContact C-N 3.34Å; G168-Y170 PolarHBondContact O-N 3.38Å; G168-I171 PolarHBondContact O-N 3.14Å; G168-I171 VanDerWaalsContact O-N 3.14Å; G168-V172 WeakPolarHBondContact O-CG2 3.29Å; G168-V172 PolarHBondContact O-N 3.15Å
169	Y	96.3	Very high	93.4	Very high	22 Å²	22	31.3 Å²	31.3	9%	0.086	17%	0.171	C	C	.	.	H	α-helix	trans	-52.7	-47.8	178.1	170.9	-98.6	0	0	0	112.6	W9 F165 L167 I171 V172 L173 Y258 Y278	W9-Y169 AromaticContact CH2-CD2 3.69Å; W9-Y169 HydrophobicContact CH2-CD2 3.69Å; W9-Y169 AromaticContact CH2-CE2 3.42Å; W9-Y169 HydrophobicContact CH2-CE2 3.42Å; W9-Y169 VanDerWaalsContact CH2-CE2 3.42Å; W9-Y169 AromaticContact CZ3-CD2 3.98Å; W9-Y169 HydrophobicContact CZ3-CD2 3.98Å; W9-Y169 AromaticContact CZ3-CE2 3.64Å; W9-Y169 HydrophobicContact CZ3-CE2 3.64Å; F165-Y169 VanDerWaalsContact O-CB 3.29Å; F165-Y169 WeakPolarHBondContact O-CB 3.5Å; F165-Y169 PolarHBondContact O-N 3.36Å; L167-Y169 VanDerWaalsContact C-N 3.31Å; L167-Y169 PolarHBondContact O-N 3.08Å; Y169-I171 VanDerWaalsContact C-N 3.32Å; Y169-I171 PolarHBondContact O-N 3.42Å; Y169-V172 PolarHBondContact O-N 3Å; Y169-L173 HydrophobicContact CE1-CD2 4.03Å; Y169-L173 VanDerWaalsContact O-CB 3.29Å; Y169-L173 WeakPolarHBondContact O-CB 3.31Å; Y169-L173 PolarHBondContact O-N 3Å; Y169-Y258 WeakPolarHBondContact OH-CE1 3.36Å; Y169-Y258 PolarHBondContact OH-OH 3.38Å; Y169-Y278 AromaticContact CD2-CE1 3.93Å; Y169-Y278 HydrophobicContact CD2-CE1 3.93Å; Y169-Y278 AromaticContact CE2-CD1 3.99Å; Y169-Y278 HydrophobicContact CE2-CD1 3.99Å; Y169-Y278 AromaticContact CE2-CE1 3.33Å; Y169-Y278 HydrophobicContact CE2-CE1 3.33Å
170	Y	96.2	Very high	93.4	Very high	18 Å²	18	30.7 Å²	30.7	7%	0.071	17%	0.169	C	C	.	.	H	α-helix	trans	-70.9	-26.9	-178	-76.5	-72.1	0	0	0	113.5	F74 Y75 S78 G166 L167 G168 L173 G174	F74-Y170 HydrophobicContact CB-CD2 3.88Å; F74-Y170 HydrophobicContact CB-CE2 3.59Å; F74-Y170 WeakPolarHBondContact O-CD2 3.06Å; Y75-Y170 HydrophobicContact CD1-CE1 4.49Å; Y75-Y170 AromaticContact CE1-CZ 3.84Å; Y75-Y170 WeakPolarHBondContact CE1-OH 3.32Å; S78-Y170 WeakPolarHBondContact OG-CD1 3.35Å; G166-Y170 VanDerWaalsContact O-CD2 3.31Å; G166-Y170 WeakPolarHBondContact O-CD2 3.49Å; L167-Y170 PolarHBondContact O-N 3.33Å; G168-Y170 VanDerWaalsContact C-N 3.34Å; G168-Y170 PolarHBondContact O-N 3.38Å; Y170-L173 HydrophobicContact CD1-CD2 4.43Å; Y170-G174 PolarHBondContact O-N 2.81Å
171	I	97.1	Very high	92.9	Very high	54 Å²	54	29.1 Å²	29.1	28%	0.277	16%	0.161	S	C	.	.	H	α-helix	trans	-68.5	-51.8	171.9	-58.8	-58.2	0	0	0	110	I77 W81 G168 Y169 L173 G174 L175	I77-I171 HydrophobicContact CG2-CD1 3.67Å; I77-I171 HydrophobicContact CG2-CG1 4.27Å; W81-I171 HydrophobicContact CB-CD1 3.89Å; W81-I171 HydrophobicContact CD2-CD1 3.77Å; W81-I171 HydrophobicContact CE3-CD1 4.28Å; W81-I171 HydrophobicContact CG-CD1 3.58Å; W81-I171 HydrophobicContact CZ2-CG2 4.06Å; W81-I171 PolarHBondContact NE1-O 3.38Å; G168-I171 PolarHBondContact O-N 3.14Å; G168-I171 VanDerWaalsContact O-N 3.14Å; Y169-I171 VanDerWaalsContact C-N 3.32Å; Y169-I171 PolarHBondContact O-N 3.42Å; I171-L173 VanDerWaalsContact C-N 3.29Å; I171-L173 PolarHBondContact O-N 3.14Å; I171-G174 PolarHBondContact O-N 2.76Å; I171-L175 HydrophobicContact CG2-CD1 4.26Å; I171-L175 WeakPolarHBondContact O-CG 3.34Å; I171-L175 PolarHBondContact O-N 2.71Å; I171-L175 VanDerWaalsContact O-N 3.16Å
172	V	97.3	Very high	92.3	Very high	54 Å²	54	27.6 Å²	27.6	33%	0.327	15%	0.15	S	C	.	.	H	α-helix	trans	-63.4	-36.1	-179.8	177.9	0	0	0	0	111.4	I5 W9 G168 Y169 L175 T176	I5-V172 HydrophobicContact CD1-CG1 3.81Å; W9-V172 HydrophobicContact CH2-CG1 4.44Å; W9-V172 HydrophobicContact CZ2-CG1 3.76Å; G168-V172 WeakPolarHBondContact O-CG2 3.29Å; G168-V172 PolarHBondContact O-N 3.15Å; Y169-V172 PolarHBondContact O-N 3Å; V172-L175 PolarHBondContact O-N 2.71Å; V172-T176 WeakPolarHBondContact O-CB 3.39Å; V172-T176 PolarHBondContact O-N 2.91Å; V172-T176 PolarHBondContact O-OG1 3.18Å
173	L	97.2	Very high	91.3	Very high	2 Å²	2	27.5 Å²	27.5	1%	0.01	15%	0.152	C	C	.	.	H	α-helix	trans	-61.3	-47	177.5	-173.6	65.5	0	0	0	112	L136 Y169 Y170 I171 L175 T176 V177 Y258 W272 V275	L136-L173 HydrophobicContact CD1-CD2 4.41Å; L136-L173 HydrophobicContact CD1-CG 4.23Å; L136-L173 HydrophobicContact CD2-CD2 3.94Å; Y169-L173 HydrophobicContact CE1-CD2 4.03Å; Y169-L173 VanDerWaalsContact O-CB 3.29Å; Y169-L173 WeakPolarHBondContact O-CB 3.31Å; Y169-L173 PolarHBondContact O-N 3Å; Y170-L173 HydrophobicContact CD1-CD2 4.43Å; I171-L173 VanDerWaalsContact C-N 3.29Å; I171-L173 PolarHBondContact O-N 3.14Å; L173-L175 PolarHBondContact O-N 2.93Å; L173-T176 WeakPolarHBondContact O-CB 3.47Å; L173-T176 PolarHBondContact O-N 3.45Å; L173-V177 PolarHBondContact O-N 3.45Å; L173-Y258 HydrophobicContact CD1-CE1 3.87Å; L173-Y258 HydrophobicContact CD2-CE1 3.95Å; L173-Y258 WeakPolarHBondContact CD2-OH 3.47Å; L173-W272 HydrophobicContact CD1-CH2 3.85Å; L173-W272 HydrophobicContact CD1-CZ3 3.96Å; L173-V275 HydrophobicContact CD1-CG1 3.74Å
174	G	96.5	Very high	90.2	Very high	0 Å²	0	28.8 Å²	28.8	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-62.5	-41.3	176.1	0	0	0	0	0	112.5	Y170 I171 T176 V177 L178	Y170-G174 PolarHBondContact O-N 2.81Å; I171-G174 PolarHBondContact O-N 2.76Å; G174-T176 VanDerWaalsContact C-N 3.33Å; G174-T176 PolarHBondContact O-N 2.77Å; G174-V177 PolarHBondContact O-N 3.02Å; G174-L178 PolarHBondContact O-N 3.2Å
175	L	96.3	Very high	88.2	Confident	13 Å²	13	33.8 Å²	33.8	7%	0.068	19%	0.186	C	C	.	.	H	α-helix	trans	-63.3	-38.7	174.4	-68.9	172.6	0	0	0	112.1	W81 L103 I106 L107 L110 I171 V172 L173 V177 L178 C179	W81-L175 HydrophobicContact CZ2-CD1 4.48Å; W81-L175 HydrophobicContact CZ2-CD2 3.86Å; W81-L175 HydrophobicContact CZ2-CG 3.99Å; L103-L175 HydrophobicContact CD1-CD2 3.64Å; I106-L175 HydrophobicContact CG2-CD1 3.94Å; I106-L175 HydrophobicContact CG2-CD2 4.25Å; L107-L175 HydrophobicContact CD2-CD2 4.32Å; L110-L175 HydrophobicContact CD1-CB 4.01Å; L110-L175 HydrophobicContact CD1-CD1 4.13Å; I171-L175 HydrophobicContact CG2-CD1 4.26Å; I171-L175 WeakPolarHBondContact O-CG 3.34Å; I171-L175 PolarHBondContact O-N 2.71Å; I171-L175 VanDerWaalsContact O-N 3.16Å; V172-L175 PolarHBondContact O-N 2.71Å; L173-L175 PolarHBondContact O-N 2.93Å; L175-V177 VanDerWaalsContact C-N 3.29Å; L175-V177 PolarHBondContact O-N 3.11Å; L175-L178 PolarHBondContact O-N 2.83Å; L175-L178 VanDerWaalsContact O-N 3.16Å; L175-C179 PolarHBondContact O-N 3.38Å; L175-C179 PolarHBondContact O-SG 3.41Å
176	T	96.1	Very high	86.1	Confident	0 Å²	0	33 Å²	33	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-61.7	-37.4	178.4	-57.5	0	0	0	0	111.9	I5 W9 V172 L173 G174 C179 S180 T271 W272 V275	I5-T176 HydrophobicContact CG1-CG2 4.33Å; W9-T176 PolarHBondContact NE1-OG1 3.46Å; V172-T176 WeakPolarHBondContact O-CB 3.39Å; V172-T176 PolarHBondContact O-N 2.91Å; V172-T176 PolarHBondContact O-OG1 3.18Å; L173-T176 WeakPolarHBondContact O-CB 3.47Å; L173-T176 PolarHBondContact O-N 3.45Å; G174-T176 VanDerWaalsContact C-N 3.33Å; G174-T176 PolarHBondContact O-N 2.77Å; T176-C179 PolarHBondContact O-N 3.27Å; T176-S180 PolarHBondContact O-N 3.05Å; T176-S180 PolarHBondContact O-OG 2.89Å; T176-S180 VanDerWaalsContact O-OG 3.08Å; T176-T271 HydrophobicContact CG2-CG2 3.75Å; T176-W272 HydrophobicContact CG2-CE3 4.4Å; T176-V275 HydrophobicContact CG2-CG2 3.89Å
177	V	94.9	Very high	83.5	Confident	0 Å²	0	37.9 Å²	37.9	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-62.3	-47.5	174.8	178.4	0	0	0	0	110.3	T129 V132 L133 L136 L173 G174 L175 C179 S180 W272	T129-V177 HydrophobicContact CG2-CG1 3.85Å; T129-V177 WeakPolarHBondContact CG2-O 3.37Å; V132-V177 HydrophobicContact CB-CG1 4.1Å; V132-V177 HydrophobicContact CG1-CB 4.5Å; V132-V177 HydrophobicContact CG1-CG1 3.77Å; V132-V177 HydrophobicContact CG1-CG2 3.81Å; L133-V177 HydrophobicContact CD2-CB 3.9Å; L133-V177 HydrophobicContact CD2-CG1 3.9Å; L133-V177 HydrophobicContact CD2-CG2 4.44Å; L133-V177 HydrophobicContact CG-CB 4.25Å; L133-V177 HydrophobicContact CG-CG1 3.67Å; L136-V177 HydrophobicContact CD1-CG2 3.53Å; L173-V177 PolarHBondContact O-N 3.45Å; G174-V177 PolarHBondContact O-N 3.02Å; L175-V177 VanDerWaalsContact C-N 3.29Å; L175-V177 PolarHBondContact O-N 3.11Å; V177-C179 VanDerWaalsContact C-N 3.29Å; V177-C179 PolarHBondContact O-N 3.14Å; V177-S180 WeakPolarHBondContact O-CB 3.26Å; V177-S180 PolarHBondContact O-N 3.26Å; V177-S180 PolarHBondContact O-OG 3.41Å; V177-W272 HydrophobicContact CG2-CE3 4.3Å; V177-W272 HydrophobicContact CG2-CH2 3.93Å; V177-W272 HydrophobicContact CG2-CZ3 3.42Å; V177-W272 VanDerWaalsContact CG2-CZ3 3.42Å
178	L	92.4	Very high	81.3	Confident	6 Å²	6	40 Å²	40	3%	0.031	26%	0.258	C	S	.	.	H	α-helix	trans	-61.8	-35.9	175.8	-67.8	-177.3	0	0	0	113	L85 Y99 L103 L107 T129 L133 G174 L175 S180	L85-L178 HydrophobicContact CB-CD1 4.5Å; L85-L178 HydrophobicContact CD1-CD1 4.05Å; L85-L178 HydrophobicContact CD2-CD1 3.9Å; L85-L178 HydrophobicContact CG-CD1 4.37Å; Y99-L178 WeakPolarHBondContact OH-CD2 3.42Å; L103-L178 HydrophobicContact CD2-CD1 4.31Å; L107-L178 HydrophobicContact CD1-CB 4.32Å; L107-L178 HydrophobicContact CD2-CB 3.86Å; T129-L178 HydrophobicContact CG2-CD2 4.25Å; L133-L178 HydrophobicContact CD1-CD2 3.71Å; L133-L178 HydrophobicContact CD1-CG 4.38Å; G174-L178 PolarHBondContact O-N 3.2Å; L175-L178 PolarHBondContact O-N 2.83Å; L175-L178 VanDerWaalsContact O-N 3.16Å; L178-S180 PolarHBondContact O-N 3.44Å
179	C	90.3	Very high	78.7	Confident	0 Å²	0	43.8 Å²	43.8	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-64.6	-22	174.4	-67.8	0	0	0	0	113.3	T111 L175 T176 V177 D181 L182 T183	T111-C179 HydrophobicContact CG2-CB 3.67Å; L175-C179 PolarHBondContact O-N 3.38Å; L175-C179 PolarHBondContact O-SG 3.41Å; T176-C179 PolarHBondContact O-N 3.27Å; V177-C179 VanDerWaalsContact C-N 3.29Å; V177-C179 PolarHBondContact O-N 3.14Å; C179-D181 PolarHBondContact O-N 2.87Å; C179-L182 PolarHBondContact O-N 2.89Å; C179-L182 VanDerWaalsContact O-N 3.12Å; C179-T183 PolarHBondContact O-N 3.35Å; C179-T183 VanDerWaalsContact O-N 3.08Å; C179-T183 PolarHBondContact O-OG1 3.24Å; C179-T183 VanDerWaalsContact O-OG1 3.13Å
180	S	85.2	Confident	76.3	Confident	9 Å²	9	49 Å²	49	6%	0.063	30%	0.303	C	S	.	.	H	α-helix	trans	-64.3	-29.1	-176.3	-62.3	0	0	0	0	112.8	T176 V177 L178 A184	T176-S180 PolarHBondContact O-N 3.05Å; T176-S180 PolarHBondContact O-OG 2.89Å; T176-S180 VanDerWaalsContact O-OG 3.08Å; V177-S180 WeakPolarHBondContact O-CB 3.26Å; V177-S180 PolarHBondContact O-N 3.26Å; V177-S180 PolarHBondContact O-OG 3.41Å; L178-S180 PolarHBondContact O-N 3.44Å; S180-A184 WeakPolarHBondContact O-CB 3.46Å; S180-A184 PolarHBondContact O-N 3.43Å
181	D	77.4	Confident	74.1	Confident	32 Å²	32	54.5 Å²	54.5	17%	0.171	33%	0.333	C	S	.	.	H	α-helix	trans	-72.8	-34.9	175	-74	-19.8	0	0	0	112.4	P125 Q126 T129 C179	P125-D181 WeakPolarHBondContact CA-OD2 3.37Å; P125-D181 WeakPolarHBondContact CB-OD2 3.49Å; Q126-D181 WeakPolarHBondContact CB-OD1 3.45Å; Q126-D181 VanDerWaalsContact CG-OD1 3.3Å; Q126-D181 WeakPolarHBondContact CG-OD1 3.24Å; Q126-D181 PolarHBondContact N-OD2 3.25Å; T129-D181 WeakPolarHBondContact CB-OD1 3.46Å; T129-D181 VanDerWaalsContact CB-OD2 3.26Å; T129-D181 WeakPolarHBondContact CB-OD2 3.3Å; T129-D181 WeakPolarHBondContact CG2-OD2 3.21Å; T129-D181 PolarHBondContact OG1-OD1 3.34Å; T129-D181 PolarHBondContact OG1-OD2 3.19Å; C179-D181 PolarHBondContact O-N 2.87Å
182	L	73.6	Confident	72.1	Confident	52 Å²	52	56 Å²	56	27%	0.272	35%	0.348	S	S	.	.	H	α-helix	trans	-78.5	-29.9	-177	-64.1	172.7	0	0	0	112.2	L107 T111 L122 C179	L107-L182 HydrophobicContact CB-CD1 3.92Å; L107-L182 HydrophobicContact CD1-CD1 4.49Å; T111-L182 HydrophobicContact CG2-CB 4.02Å; T111-L182 HydrophobicContact CG2-CD1 4.01Å; L122-L182 HydrophobicContact CD2-CD2 4.25Å; L122-L182 HydrophobicContact CG-CD2 4.14Å; C179-L182 PolarHBondContact O-N 2.89Å; C179-L182 VanDerWaalsContact O-N 3.12Å
183	T	68	Low	70.2	Confident	36 Å²	36	60 Å²	60	22%	0.221	36%	0.363	C	S	.	.	H	α-helix	trans	-91.9	-7.5	179	59.3	0	0	0	0	113.2	T111 C179 K185	T111-T183 HydrophobicContact CG2-CG2 4.01Å; C179-T183 PolarHBondContact O-N 3.35Å; C179-T183 VanDerWaalsContact O-N 3.08Å; C179-T183 PolarHBondContact O-OG1 3.24Å; C179-T183 VanDerWaalsContact O-OG1 3.13Å; T183-K185 PolarHBondContact O-N 3.41Å
184	A	67.3	Low	68.7	Low	54 Å²	54	61.1 Å²	61.1	45%	0.446	37%	0.371	S	S	.	.			trans	-65	90.5	173.6	0	0	0	0	0	110.7	S180 G186	S180-A184 WeakPolarHBondContact O-CB 3.46Å; S180-A184 PolarHBondContact O-N 3.43Å; A184-G186 PolarHBondContact O-N 3.46Å
185	K	53.2	Low	67.9	Low	206 Å²	206	65.3 Å²	65.3	90%	0.896	39%	0.394	S	S	*	.			trans	-76.8	97.5	174	-70.2	-179.6	179.6	177.9	0	109.9	T183	T183-K185 PolarHBondContact O-N 3.41Å
186	G	47.5	Very low	67.4	Low	58 Å²	58	74.4 Å²	74.4	60%	0.598	43%	0.427	S	S	*	.	S	Bend	trans	162.6	144.1	162	0	0	0	0	0	114.3	A184	A184-G186 PolarHBondContact O-N 3.46Å
187	P	39.7	Very low	67.1	Low	114 Å²	114	76.9 Å²	76.9	74%	0.74	44%	0.44	S	S	*	.			trans	-61.3	144.7	166.5	28.1	-30.9	0	0	0	108.9	T189	P187-T189 VanDerWaalsContact C-N 3.25Å; P187-T189 PolarHBondContact O-N 3.4Å; P187-T189 PolarHBondContact O-OG1 3.19Å
188	G	48.8	Very low	66.8	Low	77 Å²	77	79.8 Å²	79.8	79%	0.794	45%	0.451	S	S	*	.	S	Bend	trans	-64	71.9	-174.6	0	0	0	0	0	114.8
189	T	42.5	Very low	66.8	Low	113 Å²	113	81.2 Å²	81.2	69%	0.693	47%	0.467	S	S	*	.			trans	-120.8	93	178.2	43.7	0	0	0	0	110	P187	P187-T189 VanDerWaalsContact C-N 3.25Å; P187-T189 PolarHBondContact O-N 3.4Å; P187-T189 PolarHBondContact O-OG1 3.19Å
190	L	44.8	Very low	67	Low	132 Å²	132	83.8 Å²	83.8	69%	0.691	49%	0.489	S	S	*	.			trans	165.3	62.5	142.4	-85.3	169.3	0	0	0	108.8	S192 S194	L190-S192 PolarHBondContact O-N 3.07Å; L190-S192 VanDerWaalsContact O-N 3.1Å; L190-S194 WeakPolarHBondContact O-CB 3.17Å; L190-S194 PolarHBondContact O-N 3.41Å
191	L	50.3	Low	67.6	Low	132 Å²	132	83.4 Å²	83.4	69%	0.691	49%	0.486	S	S	*	.	H	α-helix	trans	-59.5	-18.1	-178.8	-84.2	152.8	0	0	0	114	D195	L191-D195 VanDerWaalsContact O-OD2 3.12Å
192	S	54.2	Low	68.5	Low	86 Å²	86	86.3 Å²	86.3	60%	0.601	50%	0.497	S	S	*	.	H	α-helix	trans	-87.1	-46.9	-178.7	173.7	0	0	0	0	114.3	L190	L190-S192 PolarHBondContact O-N 3.07Å; L190-S192 VanDerWaalsContact O-N 3.1Å
193	H	57.6	Low	69.6	Low	137 Å²	137	88.5 Å²	88.5	63%	0.634	51%	0.512	S	S	*	.	H	α-helix	trans	-75.9	-30.1	-178.5	-101	-78.7	0	0	0	113	D195 I197	H193-D195 VanDerWaalsContact C-N 3.34Å; H193-D195 PolarHBondContact O-N 3.48Å; H193-I197 WeakPolarHBondContact O-CG1 3.31Å
194	S	67.1	Low	71.1	Confident	26 Å²	26	89 Å²	89	18%	0.182	51%	0.514	C	S	.	.	H	α-helix	trans	-67.9	-33.1	-178	-169.5	0	0	0	0	112.3	L190 I197 R198	L190-S194 WeakPolarHBondContact O-CB 3.17Å; L190-S194 PolarHBondContact O-N 3.41Å; S194-I197 PolarHBondContact O-N 3.5Å; S194-R198 WeakPolarHBondContact O-CB 3.21Å; S194-R198 VanDerWaalsContact O-CG 3.23Å; S194-R198 WeakPolarHBondContact O-CG 3.39Å; S194-R198 PolarHBondContact O-N 3.22Å; S194-R198 PolarHBondContact O-NE 3.08Å; S194-R198 VanDerWaalsContact OG-CZ 3.28Å; S194-R198 PolarHBondContact OG-NE 3.19Å; S194-R198 PolarHBondContact OG-NH2 2.76Å
195	D	78.6	Confident	72.6	Confident	88 Å²	88	86.7 Å²	86.7	47%	0.471	49%	0.493	S	S	.	.	H	α-helix	trans	-69.9	-40.2	-177	-73.5	-15.2	0	0	0	113.5	L191 H193 R198 G199	L191-D195 VanDerWaalsContact O-OD2 3.12Å; H193-D195 VanDerWaalsContact C-N 3.34Å; H193-D195 PolarHBondContact O-N 3.48Å; D195-R198 PolarHBondContact O-N 3.04Å; D195-R198 IonicContact OD1-CZ 3.94Å; D195-R198 VanDerWaalsContact OD1-CZ 3.26Å; D195-R198 IonicContact OD1-NE 3.92Å; D195-R198 PolarHBondContact OD1-NE 2.95Å; D195-R198 IonicContact OD1-NH2 2.74Å; D195-R198 PolarHBondContact OD1-NH2 2.77Å; D195-G199 PolarHBondContact O-N 3.12Å
196	W	86.2	Confident	74.7	Confident	205 Å²	205	80.6 Å²	80.6	78%	0.777	47%	0.47	S	S	*	.	H	α-helix	trans	-65.2	-40	175.3	-69.3	103.6	0	0	0	112.2	R198 G199 A200	W196-R198 VanDerWaalsContact C-N 3.34Å; W196-G199 PolarHBondContact O-N 3.36Å; W196-A200 WeakPolarHBondContact O-CB 3.43Å; W196-A200 PolarHBondContact O-N 2.91Å
197	I	89.1	Confident	77.1	Confident	51 Å²	51	80.4 Å²	80.4	26%	0.262	46%	0.462	S	S	.	.	H	α-helix	trans	-64	-43.4	176	-63.7	170.4	0	0	0	109.8	H193 S194 A200 G201 F263	H193-I197 WeakPolarHBondContact O-CG1 3.31Å; S194-I197 PolarHBondContact O-N 3.5Å; I197-A200 PolarHBondContact O-N 2.62Å; I197-G201 PolarHBondContact O-N 3.07Å; I197-F263 HydrophobicContact CG2-CB 3.9Å; I197-F263 HydrophobicContact CG2-CD1 4.18Å; I197-F263 HydrophobicContact CG2-CG 4.22Å
198	R	90.1	Very high	79.9	Confident	61 Å²	61	75 Å²	75	23%	0.23	43%	0.428	C	S	.	.	H	α-helix	trans	-61.4	-45.6	175.7	-73.5	-174.8	-83.3	-143.3	-0.8	112	S194 D195 W196 G201 F202 T264	S194-R198 WeakPolarHBondContact O-CB 3.21Å; S194-R198 VanDerWaalsContact O-CG 3.23Å; S194-R198 WeakPolarHBondContact O-CG 3.39Å; S194-R198 PolarHBondContact O-N 3.22Å; S194-R198 PolarHBondContact O-NE 3.08Å; S194-R198 VanDerWaalsContact OG-CZ 3.28Å; S194-R198 PolarHBondContact OG-NE 3.19Å; S194-R198 PolarHBondContact OG-NH2 2.76Å; D195-R198 PolarHBondContact O-N 3.04Å; D195-R198 IonicContact OD1-CZ 3.94Å; D195-R198 VanDerWaalsContact OD1-CZ 3.26Å; D195-R198 IonicContact OD1-NE 3.92Å; D195-R198 PolarHBondContact OD1-NE 2.95Å; D195-R198 IonicContact OD1-NH2 2.74Å; D195-R198 PolarHBondContact OD1-NH2 2.77Å; W196-R198 VanDerWaalsContact C-N 3.34Å; R198-G201 PolarHBondContact O-N 3.33Å; R198-F202 PolarHBondContact O-N 3Å; R198-T264 WeakPolarHBondContact CG-O 3.29Å
199	G	91.6	Very high	82.3	Confident	37 Å²	37	72 Å²	72	38%	0.381	39%	0.394	S	S	.	.	H	α-helix	trans	-61	-44.5	175.1	0	0	0	0	0	112.6	D195 W196 G201 F202 V203	D195-G199 PolarHBondContact O-N 3.12Å; W196-G199 PolarHBondContact O-N 3.36Å; G199-G201 VanDerWaalsContact C-N 3.31Å; G199-G201 PolarHBondContact O-N 2.89Å; G199-F202 PolarHBondContact O-N 3.24Å; G199-V203 WeakPolarHBondContact O-CG2 3.47Å; G199-V203 PolarHBondContact O-N 2.89Å
200	A	94.7	Very high	85	Confident	54 Å²	54	71.2 Å²	71.2	45%	0.446	39%	0.386	S	S	.	.	H	α-helix	trans	-61.7	-39.8	174.6	0	0	0	0	0	111.9	W196 I197 V203 L204	W196-A200 WeakPolarHBondContact O-CB 3.43Å; W196-A200 PolarHBondContact O-N 2.91Å; I197-A200 PolarHBondContact O-N 2.62Å; A200-V203 PolarHBondContact O-N 3.28Å; A200-L204 VanDerWaalsContact O-CB 3.29Å; A200-L204 WeakPolarHBondContact O-CB 3.27Å; A200-L204 PolarHBondContact O-N 3.22Å
201	G	96.8	Very high	87.5	Confident	0 Å²	0	65.6 Å²	65.6	0%	0	36%	0.356	C	S	.	.	H	α-helix	trans	-58.1	-46.4	171.9	0	0	0	0	0	112.4	I197 R198 G199 L204 F205 S260	I197-G201 PolarHBondContact O-N 3.07Å; R198-G201 PolarHBondContact O-N 3.33Å; G199-G201 VanDerWaalsContact C-N 3.31Å; G199-G201 PolarHBondContact O-N 2.89Å; G201-L204 PolarHBondContact O-N 2.84Å; G201-F205 WeakPolarHBondContact O-CB 3.44Å; G201-F205 PolarHBondContact O-N 3.36Å; G201-S260 WeakPolarHBondContact CA-O 3.44Å; G201-S260 VanDerWaalsContact O-CB 3.25Å; G201-S260 WeakPolarHBondContact O-CB 3.2Å
202	F	96.1	Very high	89.7	Confident	93 Å²	93	59.5 Å²	59.5	41%	0.408	32%	0.324	S	S	.	.	H	α-helix	trans	-64	-44.6	177	-176	-99	0	0	0	112.6	L135 R198 G199 L204 F205 I206	L135-F202 HydrophobicContact CD1-CD2 4.36Å; L135-F202 HydrophobicContact CD2-CD2 4.01Å; L135-F202 HydrophobicContact CD2-CE2 3.88Å; R198-F202 PolarHBondContact O-N 3Å; G199-F202 PolarHBondContact O-N 3.24Å; F202-L204 PolarHBondContact O-N 2.94Å; F202-F205 WeakPolarHBondContact O-CB 3.37Å; F202-F205 PolarHBondContact O-N 3.1Å; F202-I206 HydrophobicContact CE1-CG1 4.18Å; F202-I206 HydrophobicContact CZ-CD1 4.28Å; F202-I206 HydrophobicContact CZ-CG1 4.34Å; F202-I206 WeakPolarHBondContact O-CG1 3.4Å; F202-I206 PolarHBondContact O-N 2.96Å; F202-I206 VanDerWaalsContact O-N 3.17Å
203	V	97.8	Very high	91.8	Very high	99 Å²	99	58.8 Å²	58.8	60%	0.6	31%	0.311	S	S	*	.	H	α-helix	trans	-62	-44.6	177.2	172.8	0	0	0	0	111.2	G199 A200 F205 I206 A207	G199-V203 WeakPolarHBondContact O-CG2 3.47Å; G199-V203 PolarHBondContact O-N 2.89Å; A200-V203 PolarHBondContact O-N 3.28Å; V203-F205 VanDerWaalsContact C-N 3.3Å; V203-F205 PolarHBondContact O-N 3.34Å; V203-I206 PolarHBondContact O-N 3.36Å; V203-A207 PolarHBondContact O-N 3.45Å
204	L	98.5	Very high	93.7	Very high	47 Å²	47	57.5 Å²	57.5	25%	0.246	31%	0.305	C	S	.	.	H	α-helix	trans	-62.4	-38.3	176.7	-179.3	61.4	0	0	0	111.6	A200 G201 F202 I206 A207 A208 L256 V259 F263	A200-L204 VanDerWaalsContact O-CB 3.29Å; A200-L204 WeakPolarHBondContact O-CB 3.27Å; A200-L204 PolarHBondContact O-N 3.22Å; G201-L204 PolarHBondContact O-N 2.84Å; F202-L204 PolarHBondContact O-N 2.94Å; L204-I206 VanDerWaalsContact C-N 3.34Å; L204-I206 PolarHBondContact O-N 3.39Å; L204-A207 PolarHBondContact O-N 3.42Å; L204-A208 WeakPolarHBondContact O-CB 3.35Å; L204-A208 PolarHBondContact O-N 3.45Å; L204-L256 HydrophobicContact CD1-CB 4.49Å; L204-V259 HydrophobicContact CD2-CG1 4.13Å; L204-F263 HydrophobicContact CD2-CD2 4.33Å; L204-F263 HydrophobicContact CD2-CE2 4.3Å
205	F	98.6	Very high	95.1	Very high	4 Å²	4	56.5 Å²	56.5	2%	0.018	30%	0.298	C	S	.	.	H	α-helix	trans	-58.3	-45.8	176.1	178.9	-94.5	0	0	0	111.6	L135 V138 H139 G201 F202 V203 S209 I257 S260 L261	L135-F205 HydrophobicContact CB-CD2 4.44Å; L135-F205 HydrophobicContact CB-CE1 4.46Å; L135-F205 HydrophobicContact CB-CE2 4.04Å; L135-F205 HydrophobicContact CB-CZ 4.05Å; L135-F205 HydrophobicContact CD1-CG 4.44Å; L135-F205 HydrophobicContact CD2-CD1 3.87Å; L135-F205 HydrophobicContact CD2-CE1 3.8Å; L135-F205 HydrophobicContact CD2-CG 4.38Å; L135-F205 HydrophobicContact CD2-CZ 4.25Å; L135-F205 WeakPolarHBondContact O-CZ 3.33Å; V138-F205 HydrophobicContact CG1-CE1 4.48Å; H139-F205 HydrophobicContact CB-CE2 4.14Å; H139-F205 HydrophobicContact CB-CZ 4Å; G201-F205 WeakPolarHBondContact O-CB 3.44Å; G201-F205 PolarHBondContact O-N 3.36Å; F202-F205 WeakPolarHBondContact O-CB 3.37Å; F202-F205 PolarHBondContact O-N 3.1Å; V203-F205 VanDerWaalsContact C-N 3.3Å; V203-F205 PolarHBondContact O-N 3.34Å; F205-S209 WeakPolarHBondContact O-CB 3.44Å; F205-S209 PolarHBondContact O-N 3.47Å; F205-S209 PolarHBondContact O-OG 3.07Å; F205-I257 HydrophobicContact CD2-CG2 3.96Å; F205-I257 HydrophobicContact CE2-CG2 3.8Å; F205-S260 VanDerWaalsContact CA-OG 3.28Å; F205-S260 WeakPolarHBondContact CA-OG 3.25Å; F205-S260 VanDerWaalsContact CB-OG 3.24Å; F205-S260 WeakPolarHBondContact CB-OG 3.47Å; F205-L261 HydrophobicContact CD2-CD2 4.07Å; F205-L261 HydrophobicContact CD2-CG 4.49Å; F205-L261 HydrophobicContact CE2-CD2 4.22Å
206	I	98.5	Very high	95.8	Very high	78 Å²	78	53.3 Å²	53.3	40%	0.4	28%	0.281	S	S	.	.	H	α-helix	trans	-65.3	-50	178.6	-60.3	-61.7	0	0	0	110.5	F202 V203 L204 A208 S209 L210	F202-I206 HydrophobicContact CE1-CG1 4.18Å; F202-I206 HydrophobicContact CZ-CD1 4.28Å; F202-I206 HydrophobicContact CZ-CG1 4.34Å; F202-I206 WeakPolarHBondContact O-CG1 3.4Å; F202-I206 PolarHBondContact O-N 2.96Å; F202-I206 VanDerWaalsContact O-N 3.17Å; V203-I206 PolarHBondContact O-N 3.36Å; L204-I206 VanDerWaalsContact C-N 3.34Å; L204-I206 PolarHBondContact O-N 3.39Å; I206-A208 PolarHBondContact O-N 2.65Å; I206-S209 PolarHBondContact O-N 3.03Å; I206-L210 HydrophobicContact CG2-CD1 4.06Å; I206-L210 HydrophobicContact CG2-CG 4.45Å; I206-L210 WeakPolarHBondContact O-CG 3.16Å; I206-L210 PolarHBondContact O-N 3.06Å
207	A	98.5	Very high	96.2	Very high	54 Å²	54	46.7 Å²	46.7	45%	0.446	26%	0.263	S	S	.	.	H	α-helix	trans	-58.8	-45.7	180	0	0	0	0	0	112.1	V203 L204 L210 L211	V203-A207 PolarHBondContact O-N 3.45Å; L204-A207 PolarHBondContact O-N 3.42Å; A207-L210 PolarHBondContact O-N 3.43Å; A207-L211 PolarHBondContact O-N 3.38Å
208	A	98.5	Very high	96.5	Very high	2 Å²	2	47.7 Å²	47.7	2%	0.017	27%	0.268	C	S	.	.	H	α-helix	trans	-67	-40.6	178	0	0	0	0	0	112.1	L204 I206 L210 L211 Q212 L256 I257	L204-A208 WeakPolarHBondContact O-CB 3.35Å; L204-A208 PolarHBondContact O-N 3.45Å; I206-A208 PolarHBondContact O-N 2.65Å; A208-L210 VanDerWaalsContact C-N 3.34Å; A208-L210 PolarHBondContact O-N 3.04Å; A208-L211 PolarHBondContact O-N 3.24Å; A208-Q212 WeakPolarHBondContact O-CB 3.49Å; A208-Q212 PolarHBondContact O-N 2.85Å; A208-L256 HydrophobicContact CB-CB 3.61Å; A208-I257 HydrophobicContact CB-CG1 3.69Å
209	S	98.4	Very high	96.6	Very high	12 Å²	12	46.8 Å²	46.8	8%	0.084	27%	0.268	C	S	.	.	H	α-helix	trans	-61.3	-42.1	175.4	-66.7	0	0	0	0	112	R142 F205 I206 Q212 H213	R142-S209 PolarHBondContact NH1-O 3.27Å; F205-S209 WeakPolarHBondContact O-CB 3.44Å; F205-S209 PolarHBondContact O-N 3.47Å; F205-S209 PolarHBondContact O-OG 3.07Å; I206-S209 PolarHBondContact O-N 3.03Å; S209-Q212 PolarHBondContact O-N 3.36Å; S209-H213 WeakPolarHBondContact O-CB 3.31Å; S209-H213 PolarHBondContact O-N 3.02Å
210	L	98.1	Very high	96.6	Very high	98 Å²	98	45.3 Å²	45.3	51%	0.513	25%	0.252	S	S	.	.	H	α-helix	trans	-64	-47.3	175.9	-70.2	173.2	0	0	0	111.6	I206 A207 A208 Q212 H213 Q214	I206-L210 HydrophobicContact CG2-CD1 4.06Å; I206-L210 HydrophobicContact CG2-CG 4.45Å; I206-L210 WeakPolarHBondContact O-CG 3.16Å; I206-L210 PolarHBondContact O-N 3.06Å; A207-L210 PolarHBondContact O-N 3.43Å; A208-L210 VanDerWaalsContact C-N 3.34Å; A208-L210 PolarHBondContact O-N 3.04Å; L210-Q212 VanDerWaalsContact C-N 3.27Å; L210-Q212 PolarHBondContact O-N 2.63Å; L210-H213 PolarHBondContact O-N 2.78Å; L210-Q214 WeakPolarHBondContact O-CB 3.45Å; L210-Q214 VanDerWaalsContact O-CG 3.28Å; L210-Q214 WeakPolarHBondContact O-CG 3.28Å; L210-Q214 PolarHBondContact O-N 3.01Å
211	L	97.8	Very high	96.4	Very high	14 Å²	14	44.8 Å²	44.8	7%	0.073	25%	0.252	C	S	.	.	H	α-helix	trans	-57.5	-43.1	176.4	173.9	58.9	0	0	0	111.5	A207 A208 S215 W242 F252 A253	A207-L211 PolarHBondContact O-N 3.38Å; A208-L211 PolarHBondContact O-N 3.24Å; L211-S215 WeakPolarHBondContact O-CB 3.46Å; L211-S215 PolarHBondContact O-N 3Å; L211-S215 PolarHBondContact O-OG 2.93Å; L211-W242 HydrophobicContact CD1-CB 3.92Å; L211-W242 HydrophobicContact CD1-CD2 3.77Å; L211-W242 HydrophobicContact CD1-CG 3.39Å; L211-W242 HydrophobicContact CD2-CD2 4.08Å; L211-W242 HydrophobicContact CD2-CE3 4.22Å; L211-W242 HydrophobicContact CD2-CZ2 4.44Å; L211-W242 HydrophobicContact CD2-CZ3 4.46Å; L211-F252 HydrophobicContact CD2-CD1 4.26Å; L211-A253 HydrophobicContact CB-CB 4.21Å; L211-A253 HydrophobicContact CD2-CB 4.03Å; L211-A253 HydrophobicContact CG-CB 3.93Å
212	Q	98.1	Very high	96.1	Very high	4 Å²	4	46.9 Å²	46.9	2%	0.019	26%	0.263	C	S	.	.	H	α-helix	trans	-64.8	-47.1	177.9	-166	176.9	48	0	0	111.6	A208 S209 L210 S215 M216 H250 A253 E254	A208-Q212 WeakPolarHBondContact O-CB 3.49Å; A208-Q212 PolarHBondContact O-N 2.85Å; S209-Q212 PolarHBondContact O-N 3.36Å; L210-Q212 VanDerWaalsContact C-N 3.27Å; L210-Q212 PolarHBondContact O-N 2.63Å; Q212-S215 WeakPolarHBondContact O-CB 3.4Å; Q212-S215 PolarHBondContact O-N 3.42Å; Q212-M216 WeakPolarHBondContact O-CG 3.27Å; Q212-M216 PolarHBondContact O-N 2.78Å; Q212-H250 HydrophobicContact CG-CB 4.23Å; Q212-H250 PolarHBondContact NE2-O 2.75Å; Q212-A253 HydrophobicContact CB-CB 3.59Å; Q212-A253 HydrophobicContact CG-CB 4.2Å; Q212-E254 PolarHBondContact NE2-OE2 3.45Å; Q212-E254 PolarHBondContact OE1-OE2 2.78Å
213	H	97.3	Very high	95.7	Very high	70 Å²	70	44.5 Å²	44.5	32%	0.324	25%	0.251	S	S	.	.	H	α-helix	trans	-59.7	-48.6	179.6	-176.6	69.6	0	0	0	111.6	E146 S209 L210 S215 M216 V217	E146-H213 WeakPolarHBondContact OE1-CB 3.37Å; E146-H213 IonicContact OE1-CE1 3.26Å; E146-H213 IonicContact OE1-CG 3.21Å; E146-H213 IonicContact OE1-ND1 2.63Å; E146-H213 PolarHBondContact OE1-ND1 3.44Å; S209-H213 WeakPolarHBondContact O-CB 3.31Å; S209-H213 PolarHBondContact O-N 3.02Å; L210-H213 PolarHBondContact O-N 2.78Å; H213-S215 VanDerWaalsContact C-N 3.28Å; H213-S215 PolarHBondContact O-N 2.99Å; H213-M216 WeakPolarHBondContact O-CB 3.3Å; H213-M216 PolarHBondContact O-N 2.92Å; H213-V217 WeakPolarHBondContact O-CG2 3.29Å; H213-V217 PolarHBondContact O-N 3Å
214	Q	96.6	Very high	95.2	Very high	111 Å²	111	42.9 Å²	42.9	52%	0.519	24%	0.236	S	C	.	.	H	α-helix	trans	-56.5	-43.9	176.4	-72.7	173.8	-9.2	0	0	111.5	L210 M216 V217 L218	L210-Q214 WeakPolarHBondContact O-CB 3.45Å; L210-Q214 VanDerWaalsContact O-CG 3.28Å; L210-Q214 WeakPolarHBondContact O-CG 3.28Å; L210-Q214 PolarHBondContact O-N 3.01Å; Q214-M216 VanDerWaalsContact C-N 3.31Å; Q214-M216 PolarHBondContact O-N 2.86Å; Q214-V217 PolarHBondContact O-N 3.4Å; Q214-L218 WeakPolarHBondContact O-CG 3.45Å; Q214-L218 PolarHBondContact O-N 3.43Å
215	S	96.5	Very high	94.4	Very high	4 Å²	4	41.3 Å²	41.3	3%	0.028	23%	0.231	C	C	.	.	H	α-helix	trans	-61.3	-39.8	177.3	-60.7	0	0	0	0	112.2	L211 Q212 H213 L219	L211-S215 WeakPolarHBondContact O-CB 3.46Å; L211-S215 PolarHBondContact O-N 3Å; L211-S215 PolarHBondContact O-OG 2.93Å; Q212-S215 WeakPolarHBondContact O-CB 3.4Å; Q212-S215 PolarHBondContact O-N 3.42Å; H213-S215 VanDerWaalsContact C-N 3.28Å; H213-S215 PolarHBondContact O-N 2.99Å; S215-L219 VanDerWaalsContact O-CG 3.31Å; S215-L219 WeakPolarHBondContact O-CG 3.28Å; S215-L219 PolarHBondContact O-N 3.18Å; S215-L219 VanDerWaalsContact O-N 3.1Å
216	M	94.9	Very high	93.3	Very high	22 Å²	22	51.8 Å²	51.8	11%	0.108	28%	0.277	C	S	.	.	H	α-helix	trans	-68.8	-40.5	177.2	-68	-64	-59.7	0	0	112.5	R143 S151 Q212 H213 Q214 L219 A220	R143-M216 VanDerWaalsContact NH1-CG 3.3Å; R143-M216 PolarHBondContact NH1-SD 3.34Å; R143-M216 VanDerWaalsContact NH1-SD 3.42Å; S151-M216 VanDerWaalsContact OG-CE 3.3Å; S151-M216 WeakPolarHBondContact OG-CE 3.48Å; Q212-M216 WeakPolarHBondContact O-CG 3.27Å; Q212-M216 PolarHBondContact O-N 2.78Å; H213-M216 WeakPolarHBondContact O-CB 3.3Å; H213-M216 PolarHBondContact O-N 2.92Å; Q214-M216 VanDerWaalsContact C-N 3.31Å; Q214-M216 PolarHBondContact O-N 2.86Å; M216-L219 PolarHBondContact O-N 3.33Å; M216-A220 WeakPolarHBondContact O-CB 3.47Å; M216-A220 PolarHBondContact O-N 3.18Å
217	V	94.5	Very high	92.3	Very high	66 Å²	66	52 Å²	52	40%	0.4	29%	0.285	S	S	.	.	H	α-helix	trans	-62.1	-45.3	176	171.4	0	0	0	0	110.7	V150 H213 Q214 L219 A220 G221	V150-V217 HydrophobicContact CG1-CG2 4.02Å; H213-V217 WeakPolarHBondContact O-CG2 3.29Å; H213-V217 PolarHBondContact O-N 3Å; Q214-V217 PolarHBondContact O-N 3.4Å; V217-L219 PolarHBondContact O-N 3.26Å; V217-A220 PolarHBondContact O-N 2.9Å; V217-G221 PolarHBondContact O-N 2.69Å
218	L	94.1	Very high	91.3	Very high	71 Å²	71	51.7 Å²	51.7	37%	0.372	29%	0.287	S	S	.	.	H	α-helix	trans	-59.9	-45.9	175.6	-71.9	171.7	0	0	0	111.6	Q214 A220 G221 L222 F243	Q214-L218 WeakPolarHBondContact O-CG 3.45Å; Q214-L218 PolarHBondContact O-N 3.43Å; L218-A220 VanDerWaalsContact C-N 3.32Å; L218-A220 PolarHBondContact O-N 3.21Å; L218-G221 PolarHBondContact O-N 3.18Å; L218-G221 VanDerWaalsContact O-N 3.15Å; L218-L222 PolarHBondContact O-N 3.34Å; L218-F243 HydrophobicContact CB-CD2 4.43Å; L218-F243 HydrophobicContact CB-CE2 4.03Å; L218-F243 HydrophobicContact CD1-CD2 3.94Å; L218-F243 HydrophobicContact CD1-CE2 4.13Å
219	L	93.3	Very high	90.4	Very high	43 Å²	43	61 Å²	61	23%	0.225	32%	0.321	C	S	.	.	H	α-helix	trans	-62.1	-37.9	177.1	-73.9	170.8	0	0	0	112.9	S215 M216 V217 L222 P238 F243	S215-L219 VanDerWaalsContact O-CG 3.31Å; S215-L219 WeakPolarHBondContact O-CG 3.28Å; S215-L219 PolarHBondContact O-N 3.18Å; S215-L219 VanDerWaalsContact O-N 3.1Å; M216-L219 PolarHBondContact O-N 3.33Å; V217-L219 PolarHBondContact O-N 3.26Å; L219-L222 HydrophobicContact CD2-CD1 4.35Å; L219-P238 HydrophobicContact CD2-CB 4.16Å; L219-P238 HydrophobicContact CD2-CG 4.29Å; L219-F243 HydrophobicContact CD1-CZ 3.95Å; L219-F243 HydrophobicContact CD2-CE1 4.16Å; L219-F243 HydrophobicContact CD2-CZ 3.84Å; L219-F243 HydrophobicContact CG-CE1 4.41Å; L219-F243 HydrophobicContact CG-CE2 4.32Å; L219-F243 HydrophobicContact CG-CZ 3.64Å
220	A	91.4	Very high	89.7	Confident	5 Å²	5	64.2 Å²	64.2	4%	0.041	34%	0.341	C	S	.	.	H	α-helix	trans	-68.4	-39	174.2	0	0	0	0	0	111.7	V150 M216 V217 L218 L222 R223 K224	V150-A220 HydrophobicContact CG1-CB 4.01Å; V150-A220 WeakPolarHBondContact O-CB 3.3Å; M216-A220 WeakPolarHBondContact O-CB 3.47Å; M216-A220 PolarHBondContact O-N 3.18Å; V217-A220 PolarHBondContact O-N 2.9Å; L218-A220 VanDerWaalsContact C-N 3.32Å; L218-A220 PolarHBondContact O-N 3.21Å; A220-L222 PolarHBondContact O-N 3.28Å; A220-R223 PolarHBondContact O-N 3.27Å; A220-K224 PolarHBondContact O-N 3.48Å
221	G	91.1	Very high	89	Confident	44 Å²	44	66 Å²	66	45%	0.454	35%	0.346	S	S	.	.	H	α-helix	trans	-58.8	-31.8	177.1	0	0	0	0	0	113.4	V217 L218 R223 K224	V217-G221 PolarHBondContact O-N 2.69Å; L218-G221 PolarHBondContact O-N 3.18Å; L218-G221 VanDerWaalsContact O-N 3.15Å; G221-R223 PolarHBondContact O-N 2.94Å; G221-R223 VanDerWaalsContact O-N 3.09Å; G221-K224 PolarHBondContact O-N 2.93Å
222	L	89.7	Confident	88.2	Confident	43 Å²	43	66.9 Å²	66.9	23%	0.225	35%	0.353	C	S	.	.	T	Hydrogen-bonded Turn	trans	-62.4	-17.8	174.7	-63.8	177	0	0	0	114.4	L218 L219 A220 P238	L218-L222 PolarHBondContact O-N 3.34Å; L219-L222 HydrophobicContact CD2-CD1 4.35Å; A220-L222 PolarHBondContact O-N 3.28Å; L222-P238 HydrophobicContact CD1-CB 3.87Å
223	R	87.8	Confident	87.3	Confident	43 Å²	43	70.6 Å²	70.6	16%	0.162	37%	0.372	C	S	.	.	T	Hydrogen-bonded Turn	trans	-111.1	-14.1	-176.6	-64.9	177.3	176.6	-160.8	-11.8	112.6	V152 A220 G221 V230 E231 T232	V152-R223 HydrophobicContact CB-CB 4.1Å; V152-R223 HydrophobicContact CG1-CB 4.09Å; V152-R223 HydrophobicContact CG2-CB 4.29Å; V152-R223 PolarHBondContact O-NH1 3.31Å; A220-R223 PolarHBondContact O-N 3.27Å; G221-R223 PolarHBondContact O-N 2.94Å; G221-R223 VanDerWaalsContact O-N 3.09Å; R223-V230 WeakPolarHBondContact O-CA 3.36Å; R223-E231 PolarHBondContact O-N 3.08Å; R223-T232 VanDerWaalsContact CB-O 3.31Å; R223-T232 WeakPolarHBondContact CB-O 3.49Å; R223-T232 PolarHBondContact O-N 2.91Å
224	K	87.1	Confident	86.3	Confident	66 Å²	66	69.8 Å²	69.8	29%	0.287	38%	0.378	S	S	.	.	B	Isolated β-bridge	trans	-105.5	140.4	-177.9	-67.1	-179.5	-178.9	-179.3	0	110.3	V150 V152 A220 G221 R229	V150-K224 PolarHBondContact O-NZ 2.91Å; V150-K224 VanDerWaalsContact O-NZ 3.1Å; V152-K224 HydrophobicContact CG2-CD 4.29Å; V152-K224 VanDerWaalsContact CG2-CE 3.41Å; V152-K224 HydrophobicContact CG2-CG 3.99Å; A220-K224 PolarHBondContact O-N 3.48Å; G221-K224 PolarHBondContact O-N 2.93Å; K224-R229 CarbonylContact C-O 3.59Å; K224-R229 VanDerWaalsContact CA-O 3.27Å; K224-R229 WeakPolarHBondContact CA-O 3.32Å
225	G	80.9	Confident	85.5	Confident	13 Å²	13	66.2 Å²	66.2	13%	0.134	36%	0.361	C	S	.	.			trans	-76.2	179.4	173.1	0	0	0	0	0	114	S227 G228 R229 E231	G225-S227 PolarHBondContact O-N 2.9Å; G225-S227 VanDerWaalsContact O-N 3.13Å; G225-G228 PolarHBondContact O-N 2.78Å; G225-R229 PolarHBondContact N-O 2.99Å; G225-E231 WeakPolarHBondContact CA-OE1 3.42Å; G225-E231 VanDerWaalsContact CA-OE2 3.28Å; G225-E231 WeakPolarHBondContact CA-OE2 3.03Å
226	K	76.4	Confident	85	Confident	225 Å²	225	72.5 Å²	72.5	98%	0.978	38%	0.384	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.9	-23.3	171	-66.4	-175.3	178.8	-179.3	0	113.1	G228	K226-G228 VanDerWaalsContact C-N 3.31Å
227	S	77.7	Confident	84.7	Confident	83 Å²	83	72.6 Å²	72.6	58%	0.58	39%	0.386	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.5	-3.1	175.5	63.6	0	0	0	0	114	G225 R229	G225-S227 PolarHBondContact O-N 2.9Å; G225-S227 VanDerWaalsContact O-N 3.13Å; S227-R229 PolarHBondContact O-N 3.03Å
228	G	77	Confident	84.5	Confident	47 Å²	47	69.5 Å²	69.5	49%	0.485	37%	0.367	S	S	.	.	S	Bend	trans	76.2	-6	-174.8	0	0	0	0	0	114.9	G225 K226	G225-G228 PolarHBondContact O-N 2.78Å; K226-G228 VanDerWaalsContact C-N 3.31Å
229	R	79.9	Confident	84.3	Confident	196 Å²	196	72.8 Å²	72.8	74%	0.74	38%	0.381	S	S	*	.	S	Bend	trans	-76.6	150.6	175	-66.2	-175.7	175.9	173.2	-0.5	111.1	K224 G225 S227 E231	K224-R229 CarbonylContact C-O 3.59Å; K224-R229 VanDerWaalsContact CA-O 3.27Å; K224-R229 WeakPolarHBondContact CA-O 3.32Å; G225-R229 PolarHBondContact N-O 2.99Å; S227-R229 PolarHBondContact O-N 3.03Å; R229-E231 PolarHBondContact O-N 3.09Å
230	V	83.5	Confident	84.1	Confident	81 Å²	81	72 Å²	72	49%	0.491	38%	0.383	S	S	.	.	B	Isolated β-bridge	trans	-69.7	114.8	175.3	-179.5	0	0	0	0	108.7	V152 R223 L233	V152-V230 HydrophobicContact CG1-CG1 3.83Å; V152-V230 HydrophobicContact CG1-CG2 3.82Å; V152-V230 HydrophobicContact CG2-CG2 3.9Å; R223-V230 WeakPolarHBondContact O-CA 3.36Å; V230-L233 HydrophobicContact CG1-CD2 4.02Å
231	E	83.6	Confident	84.2	Confident	135 Å²	135	74.7 Å²	74.7	63%	0.631	41%	0.411	S	S	*	.			trans	-98.9	-28.1	179.5	-72.1	-176.8	170.7	0	0	111.9	R223 G225 R229	R223-E231 PolarHBondContact O-N 3.08Å; G225-E231 WeakPolarHBondContact CA-OE1 3.42Å; G225-E231 VanDerWaalsContact CA-OE2 3.28Å; G225-E231 WeakPolarHBondContact CA-OE2 3.03Å; R229-E231 PolarHBondContact O-N 3.09Å
232	T	81.4	Confident	84.3	Confident	33 Å²	33	77.5 Å²	77.5	20%	0.202	41%	0.408	C	S	.	.			trans	-153	146.6	-178.3	-169.6	0	0	0	0	112.7	R223 A234	R223-T232 VanDerWaalsContact CB-O 3.31Å; R223-T232 WeakPolarHBondContact CB-O 3.49Å; R223-T232 PolarHBondContact O-N 2.91Å; T232-A234 VanDerWaalsContact OG1-CB 3.23Å; T232-A234 WeakPolarHBondContact OG1-CB 3.43Å; T232-A234 PolarHBondContact OG1-N 2.79Å
233	L	79.1	Confident	84.6	Confident	82 Å²	82	75.5 Å²	75.5	43%	0.429	40%	0.397	S	S	.	.			trans	-99.6	-0.5	167.2	-59.2	-179.5	0	0	0	112	V152 V230	V152-L233 HydrophobicContact CG1-CD2 3.9Å; V230-L233 HydrophobicContact CG1-CD2 4.02Å
234	A	76.9	Confident	84.9	Confident	53 Å²	53	76.9 Å²	76.9	44%	0.438	41%	0.405	S	S	.	.			trans	-61.9	140.6	179.4	0	0	0	0	0	110.7	T232 R236	T232-A234 VanDerWaalsContact OG1-CB 3.23Å; T232-A234 WeakPolarHBondContact OG1-CB 3.43Å; T232-A234 PolarHBondContact OG1-N 2.79Å; A234-R236 PolarHBondContact O-N 3.44Å
235	H	79.6	Confident	85.2	Confident	36 Å²	36	76.9 Å²	76.9	17%	0.167	41%	0.408	C	S	.	.			trans	-72.4	128.8	173.8	-167.7	-13.4	0	0	0	109.5	K50 Y294 Y298	K50-H235 VanDerWaalsContact CD-CD2 3.48Å; K50-H235 WeakPolarHBondContact CD-CD2 3.28Å; K50-H235 WeakPolarHBondContact CD-NE2 3.32Å; K50-H235 PolarHBondContact NZ-CE1 3.34Å; K50-H235 PolarHBondContact NZ-NE2 2.88Å; H235-Y294 AromaticContact CE1-CE1 3.08Å; H235-Y294 WeakPolarHBondContact CE1-CE1 3.47Å; H235-Y294 AromaticContact CE1-CZ 3.46Å; H235-Y294 VanDerWaalsContact CE1-CZ 3.46Å; H235-Y294 PolarHBondContact CE1-OH 2.85Å; H235-Y294 VanDerWaalsContact CE1-OH 3.28Å; H235-Y294 AromaticContact NE2-CE1 3.51Å; H235-Y294 AromaticContact NE2-CZ 3.78Å; H235-Y298 WeakPolarHBondContact CB-OH 3.25Å; H235-Y298 PolarHBondContact O-OH 3.33Å
236	R	85.6	Confident	86	Confident	135 Å²	135	76.2 Å²	76.2	51%	0.509	40%	0.402	S	S	.	.			trans	-121	158.9	168.5	-61.6	-177.8	-178.8	179.6	0.7	111.3	A234	A234-R236 PolarHBondContact O-N 3.44Å
237	V	88.8	Confident	86.9	Confident	25 Å²	25	65.5 Å²	65.5	15%	0.152	36%	0.355	C	S	.	.			trans	-75.1	127.1	173.9	178.8	0	0	0	0	108.4	Y294 Y298 Y301	V237-Y294 HydrophobicContact CG2-CD1 4.19Å; V237-Y294 HydrophobicContact CG2-CE1 4.47Å; V237-Y298 HydrophobicContact CG2-CD1 3.81Å; V237-Y298 HydrophobicContact CG2-CD2 3.46Å; V237-Y298 VanDerWaalsContact CG2-CD2 3.46Å; V237-Y298 HydrophobicContact CG2-CE1 4.11Å; V237-Y298 HydrophobicContact CG2-CE2 3.8Å; V237-Y298 HydrophobicContact CG2-CG 3.48Å; V237-Y298 VanDerWaalsContact CG2-CG 3.48Å; V237-Y301 HydrophobicContact CG1-CD2 3.88Å; V237-Y301 HydrophobicContact CG1-CE2 3.83Å; V237-Y301 HydrophobicContact CG2-CD2 4.15Å
238	P	90	Very high	87.7	Confident	1 Å²	1	61.6 Å²	61.6	1%	0.006	33%	0.327	C	S	.	.			trans	-72.2	139	174.1	27.8	-32.6	0	0	0	111.2	L219 L222 F243 Y294 R305	L219-P238 HydrophobicContact CD2-CB 4.16Å; L219-P238 HydrophobicContact CD2-CG 4.29Å; L222-P238 HydrophobicContact CD1-CB 3.87Å; P238-F243 HydrophobicContact CB-CB 4.22Å; P238-F243 HydrophobicContact CB-CD1 3.56Å; P238-F243 HydrophobicContact CB-CD2 3.98Å; P238-F243 HydrophobicContact CB-CE1 3.78Å; P238-F243 HydrophobicContact CB-CE2 4.21Å; P238-F243 HydrophobicContact CB-CG 3.66Å; P238-F243 HydrophobicContact CB-CZ 4.13Å; P238-F243 HydrophobicContact CG-CB 4.46Å; P238-F243 HydrophobicContact CG-CD1 3.33Å; P238-F243 HydrophobicContact CG-CE1 3.55Å; P238-F243 HydrophobicContact CG-CG 3.93Å; P238-F243 HydrophobicContact CG-CZ 4.35Å; P238-Y294 VanDerWaalsContact CD-OH 3.28Å; P238-Y294 WeakPolarHBondContact CD-OH 3.49Å; P238-R305 PolarHBondContact O-NH1 3.13Å
239	E	88.9	Confident	88.7	Confident	140 Å²	140	59.3 Å²	59.3	65%	0.654	30%	0.304	S	S	*	.			trans	-129.2	154.4	176.4	-66.2	177	178.8	0	0	109.2	E244	E239-E244 WeakPolarHBondContact CA-OE1 3.47Å
240	G	90.4	Very high	89.5	Confident	27 Å²	27	51 Å²	51	28%	0.278	27%	0.274	S	S	.	.	S	Bend	trans	92.5	153	179.4	0	0	0	0	0	115.1	W242 F243 E244	G240-W242 PolarHBondContact O-N 2.85Å; G240-F243 WeakPolarHBondContact O-CB 3.48Å; G240-F243 PolarHBondContact O-N 3.4Å; G240-E244 PolarHBondContact N-OE1 3Å
241	G	92.1	Very high	90.1	Very high	60 Å²	60	48.9 Å²	48.9	62%	0.619	26%	0.257	S	S	*	.	G	3₁₀ helix	trans	57.3	-136.4	180	0	0	0	0	0	112.4	F243 E244	G241-F243 PolarHBondContact O-N 3.07Å; G241-E244 PolarHBondContact O-N 2.62Å
242	W	94.3	Very high	90.8	Very high	104 Å²	104	43.9 Å²	43.9	39%	0.394	23%	0.233	S	C	.	.	G	3₁₀ helix	trans	-73.1	-9.9	-178	-74.8	65.8	0	0	0	114.1	L211 G240 E244 L245 V246 P249 F252 P310	L211-W242 HydrophobicContact CD1-CB 3.92Å; L211-W242 HydrophobicContact CD1-CD2 3.77Å; L211-W242 HydrophobicContact CD1-CG 3.39Å; L211-W242 HydrophobicContact CD2-CD2 4.08Å; L211-W242 HydrophobicContact CD2-CE3 4.22Å; L211-W242 HydrophobicContact CD2-CZ2 4.44Å; L211-W242 HydrophobicContact CD2-CZ3 4.46Å; G240-W242 PolarHBondContact O-N 2.85Å; W242-E244 PolarHBondContact O-N 3.28Å; W242-L245 HydrophobicContact CE3-CD1 4.41Å; W242-L245 PolarHBondContact O-N 3.44Å; W242-L245 VanDerWaalsContact O-N 3.11Å; W242-V246 PolarHBondContact O-N 3.45Å; W242-P249 HydrophobicContact CB-CB 3.55Å; W242-P249 HydrophobicContact CB-CG 4.21Å; W242-F252 HydrophobicContact CE3-CD1 4.41Å; W242-F252 HydrophobicContact CH2-CE1 4.28Å; W242-F252 HydrophobicContact CZ3-CD1 4.04Å; W242-F252 AromaticContact CZ3-CE1 3.71Å; W242-F252 HydrophobicContact CZ3-CE1 3.71Å; W242-P310 HydrophobicContact CE3-CG 4.24Å; W242-P310 HydrophobicContact CZ3-CG 3.89Å
243	F	95.4	Very high	91.6	Very high	0 Å²	0	42.3 Å²	42.3	0%	0	22%	0.224	C	C	.	.	G	3₁₀ helix	trans	-65.5	-19.7	172.8	-74.6	-76.7	0	0	0	112.5	L218 L219 P238 G240 G241 L245 V246 S247 P249 R305	L218-F243 HydrophobicContact CB-CD2 4.43Å; L218-F243 HydrophobicContact CB-CE2 4.03Å; L218-F243 HydrophobicContact CD1-CD2 3.94Å; L218-F243 HydrophobicContact CD1-CE2 4.13Å; L219-F243 HydrophobicContact CD1-CZ 3.95Å; L219-F243 HydrophobicContact CD2-CE1 4.16Å; L219-F243 HydrophobicContact CD2-CZ 3.84Å; L219-F243 HydrophobicContact CG-CE1 4.41Å; L219-F243 HydrophobicContact CG-CE2 4.32Å; L219-F243 HydrophobicContact CG-CZ 3.64Å; P238-F243 HydrophobicContact CB-CB 4.22Å; P238-F243 HydrophobicContact CB-CD1 3.56Å; P238-F243 HydrophobicContact CB-CD2 3.98Å; P238-F243 HydrophobicContact CB-CE1 3.78Å; P238-F243 HydrophobicContact CB-CE2 4.21Å; P238-F243 HydrophobicContact CB-CG 3.66Å; P238-F243 HydrophobicContact CB-CZ 4.13Å; P238-F243 HydrophobicContact CG-CB 4.46Å; P238-F243 HydrophobicContact CG-CD1 3.33Å; P238-F243 HydrophobicContact CG-CE1 3.55Å; P238-F243 HydrophobicContact CG-CG 3.93Å; P238-F243 HydrophobicContact CG-CZ 4.35Å; G240-F243 WeakPolarHBondContact O-CB 3.48Å; G240-F243 PolarHBondContact O-N 3.4Å; G241-F243 PolarHBondContact O-N 3.07Å; F243-L245 VanDerWaalsContact C-N 3.26Å; F243-L245 PolarHBondContact O-N 3.12Å; F243-V246 CarbonylContact C-O 3.6Å; F243-V246 WeakPolarHBondContact CA-O 3.34Å; F243-S247 WeakPolarHBondContact CE1-O 3.2Å; F243-P249 HydrophobicContact CD1-CG 3.61Å; F243-P249 HydrophobicContact CD2-CG 3.89Å; F243-P249 HydrophobicContact CE1-CG 3.56Å; F243-P249 HydrophobicContact CE2-CG 3.8Å; F243-P249 HydrophobicContact CG-CG 3.79Å; F243-P249 HydrophobicContact CZ-CG 3.62Å; F243-R305 WeakPolarHBondContact O-CD 3.33Å; F243-R305 PolarHBondContact O-NE 3.41Å; F243-R305 PolarHBondContact O-NH1 2.97Å
244	E	94.1	Very high	92.5	Very high	72 Å²	72	39 Å²	39	34%	0.336	21%	0.206	S	C	.	.	G	3₁₀ helix	trans	-67.9	-25.9	173.1	-61.6	-48.6	138.6	0	0	113.2	E239 G240 G241 W242 H304 R305	E239-E244 WeakPolarHBondContact CA-OE1 3.47Å; G240-E244 PolarHBondContact N-OE1 3Å; G241-E244 PolarHBondContact O-N 2.62Å; W242-E244 PolarHBondContact O-N 3.28Å; E244-H304 PolarHBondContact O-NE2 3.42Å; E244-H304 VanDerWaalsContact O-NE2 3.14Å; E244-R305 WeakPolarHBondContact O-CG 3.27Å; E244-R305 IonicContact OE1-NH2 3.82Å; E244-R305 PolarHBondContact OE1-NH2 3.11Å; E244-R305 VanDerWaalsContact OE1-NH2 3.15Å; E244-R305 IonicContact OE2-CZ 3.89Å; E244-R305 IonicContact OE2-NE 2.93Å; E244-R305 IonicContact OE2-NH2 3.65Å; E244-R305 PolarHBondContact OE2-NH2 3.01Å
245	L	94.2	Very high	93.6	Very high	66 Å²	66	37.2 Å²	37.2	35%	0.346	19%	0.189	S	C	.	.	T	Hydrogen-bonded Turn	trans	-93.9	-40.2	179.7	-59.1	177.8	0	0	0	111.8	W242 F243 R305 R306 F311	W242-L245 HydrophobicContact CE3-CD1 4.41Å; W242-L245 PolarHBondContact O-N 3.44Å; W242-L245 VanDerWaalsContact O-N 3.11Å; F243-L245 VanDerWaalsContact C-N 3.26Å; F243-L245 PolarHBondContact O-N 3.12Å; L245-R305 WeakPolarHBondContact O-CA 3.42Å; L245-R306 PolarHBondContact O-N 2.9Å; L245-F311 HydrophobicContact CD2-CE1 4.49Å; L245-F311 HydrophobicContact CD2-CZ 4.18Å
246	V	96.2	Very high	94.5	Very high	0 Å²	0	37.3 Å²	37.3	0%	0	19%	0.191	C	C	.	.	B	Isolated β-bridge	trans	-140.5	151.4	-171.4	-66.8	0	0	0	0	112.9	W242 F243 C248 P249 R306 F308 P310	W242-V246 PolarHBondContact O-N 3.45Å; F243-V246 CarbonylContact C-O 3.6Å; F243-V246 WeakPolarHBondContact CA-O 3.34Å; V246-C248 VanDerWaalsContact C-N 3.32Å; V246-C248 PolarHBondContact O-N 2.94Å; V246-P249 HydrophobicContact CG2-CB 3.8Å; V246-P249 HydrophobicContact CG2-CG 4.43Å; V246-R306 CarbonylContact C-O 3.57Å; V246-R306 WeakPolarHBondContact CA-O 3.31Å; V246-R306 HydrophobicContact CG1-CB 4.08Å; V246-F308 WeakPolarHBondContact CG1-O 3.29Å; V246-P310 HydrophobicContact CG1-CB 4.27Å; V246-P310 HydrophobicContact CG1-CG 3.95Å
247	S	95.4	Very high	95.1	Very high	0 Å²	0	30.9 Å²	30.9	0%	0	17%	0.167	C	C	.	.	S	Bend	trans	-67.5	-32.8	177.8	-48.9	0	0	0	0	113	F243 H291 Y301 R306 A307	F243-S247 WeakPolarHBondContact CE1-O 3.2Å; S247-H291 PolarHBondContact OG-ND1 3.43Å; S247-Y301 WeakPolarHBondContact CB-OH 3.33Å; S247-Y301 PolarHBondContact OG-OH 3.26Å; S247-R306 PolarHBondContact N-O 3.46Å; S247-R306 PolarHBondContact OG-O 3.28Å; S247-A307 WeakPolarHBondContact CB-O 3.39Å; S247-A307 PolarHBondContact N-O 3.12Å
248	C	95.9	Very high	95.5	Very high	0 Å²	0	29.8 Å²	29.8	0%	0	16%	0.16	C	C	.	.			trans	-131.5	64.1	-172.1	-51.3	0	0	0	0	113	V246 H250 Y251 F252 C290 A307 F308	V246-C248 VanDerWaalsContact C-N 3.32Å; V246-C248 PolarHBondContact O-N 2.94Å; C248-H250 PolarHBondContact O-N 3.36Å; C248-Y251 HydrophobicContact CB-CD2 3.31Å; C248-Y251 HydrophobicContact CB-CE2 3.86Å; C248-Y251 HydrophobicContact CB-CG 3.85Å; C248-Y251 WeakPolarHBondContact O-CB 3.37Å; C248-Y251 PolarHBondContact O-N 3.28Å; C248-F252 PolarHBondContact O-N 3.08Å; C248-C290 WeakPolarHBondContact SG-CB 3.19Å; C248-C290 PolarHBondContact SG-SG 2.97Å; C248-A307 PolarHBondContact N-O 3.28Å; C248-F308 HydrophobicContact CB-CB 4.04Å
249	P	97.1	Very high	95.9	Very high	0 Å²	0	31 Å²	31	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-61.2	-28.4	179.4	26.3	-34.5	0	0	0	113.3	W242 F243 V246 Y251 F252 A253	W242-P249 HydrophobicContact CB-CB 3.55Å; W242-P249 HydrophobicContact CB-CG 4.21Å; F243-P249 HydrophobicContact CD1-CG 3.61Å; F243-P249 HydrophobicContact CD2-CG 3.89Å; F243-P249 HydrophobicContact CE1-CG 3.56Å; F243-P249 HydrophobicContact CE2-CG 3.8Å; F243-P249 HydrophobicContact CG-CG 3.79Å; F243-P249 HydrophobicContact CZ-CG 3.62Å; V246-P249 HydrophobicContact CG2-CB 3.8Å; V246-P249 HydrophobicContact CG2-CG 4.43Å; P249-Y251 VanDerWaalsContact C-N 3.29Å; P249-Y251 PolarHBondContact O-N 3.07Å; P249-F252 WeakPolarHBondContact O-CB 3.23Å; P249-F252 PolarHBondContact O-N 3.11Å; P249-A253 WeakPolarHBondContact O-CB 3.22Å; P249-A253 PolarHBondContact O-N 3.4Å
250	H	96.6	Very high	96.4	Very high	21 Å²	21	24.4 Å²	24.4	10%	0.097	14%	0.136	C	C	.	.	H	α-helix	trans	-65.7	-27	174.5	56	-75.7	0	0	0	113.8	Q212 C248 E254	Q212-H250 HydrophobicContact CG-CB 4.23Å; Q212-H250 PolarHBondContact NE2-O 2.75Å; C248-H250 PolarHBondContact O-N 3.36Å; H250-E254 PolarHBondContact O-N 2.86Å; H250-E254 VanDerWaalsContact O-N 3.16Å
251	Y	97.4	Very high	96.7	Very high	36 Å²	36	23.1 Å²	23.1	14%	0.141	12%	0.123	C	C	.	.	H	α-helix	trans	-78.4	-34.8	173.6	-65.1	-19.1	0	0	0	111.6	Y48 C248 P249 E254 L255 A286	Y48-Y251 PolarHBondContact OH-OH 3.33Å; Y48-Y251 VanDerWaalsContact OH-OH 3.04Å; C248-Y251 HydrophobicContact CB-CD2 3.31Å; C248-Y251 HydrophobicContact CB-CE2 3.86Å; C248-Y251 HydrophobicContact CB-CG 3.85Å; C248-Y251 WeakPolarHBondContact O-CB 3.37Å; C248-Y251 PolarHBondContact O-N 3.28Å; P249-Y251 VanDerWaalsContact C-N 3.29Å; P249-Y251 PolarHBondContact O-N 3.07Å; Y251-E254 PolarHBondContact O-N 3.13Å; Y251-L255 PolarHBondContact O-N 3.24Å; Y251-L255 VanDerWaalsContact O-N 3.08Å; Y251-A286 HydrophobicContact CD2-CB 4.33Å; Y251-A286 HydrophobicContact CE2-CB 3.8Å
252	F	97.8	Very high	96.9	Very high	30 Å²	30	20.3 Å²	20.3	13%	0.132	9%	0.094	C	C	.	.	H	α-helix	trans	-65.5	-44.4	172.7	179.9	-117.5	0	0	0	111.3	L211 W242 C248 P249 E254 L255 L256 F308 I309	L211-F252 HydrophobicContact CD2-CD1 4.26Å; W242-F252 HydrophobicContact CE3-CD1 4.41Å; W242-F252 HydrophobicContact CH2-CE1 4.28Å; W242-F252 HydrophobicContact CZ3-CD1 4.04Å; W242-F252 AromaticContact CZ3-CE1 3.71Å; W242-F252 HydrophobicContact CZ3-CE1 3.71Å; C248-F252 PolarHBondContact O-N 3.08Å; P249-F252 WeakPolarHBondContact O-CB 3.23Å; P249-F252 PolarHBondContact O-N 3.11Å; F252-E254 VanDerWaalsContact C-N 3.3Å; F252-E254 PolarHBondContact O-N 2.86Å; F252-L255 WeakPolarHBondContact O-CB 3.05Å; F252-L255 PolarHBondContact O-N 3.05Å; F252-L256 HydrophobicContact CD1-CD1 4.08Å; F252-L256 HydrophobicContact CE1-CD1 3.57Å; F252-L256 HydrophobicContact CE1-CG 4.22Å; F252-L256 HydrophobicContact CE2-CD2 4.36Å; F252-L256 HydrophobicContact CE2-CG 4.34Å; F252-L256 HydrophobicContact CZ-CD1 3.82Å; F252-L256 HydrophobicContact CZ-CD2 4.15Å; F252-L256 HydrophobicContact CZ-CG 4.09Å; F252-L256 WeakPolarHBondContact O-CG 3.4Å; F252-L256 PolarHBondContact O-N 2.92Å; F252-F308 HydrophobicContact CB-CD2 3.94Å; F252-F308 VanDerWaalsContact CB-O 3.31Å; F252-F308 WeakPolarHBondContact CB-O 3.4Å; F252-I309 HydrophobicContact CD2-CG1 4.33Å; F252-I309 HydrophobicContact CE2-CG2 4.42Å
253	A	98.1	Very high	96.9	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-59.5	-40.4	174.1	0	0	0	0	0	112.2	L211 Q212 P249 L256 I257	L211-A253 HydrophobicContact CB-CB 4.21Å; L211-A253 HydrophobicContact CD2-CB 4.03Å; L211-A253 HydrophobicContact CG-CB 3.93Å; Q212-A253 HydrophobicContact CB-CB 3.59Å; Q212-A253 HydrophobicContact CG-CB 4.2Å; P249-A253 WeakPolarHBondContact O-CB 3.22Å; P249-A253 PolarHBondContact O-N 3.4Å; A253-L256 PolarHBondContact O-N 3.25Å; A253-I257 WeakPolarHBondContact O-CG1 3.48Å; A253-I257 PolarHBondContact O-N 3.28Å
254	E	98.2	Very high	96.8	Very high	12 Å²	12	18.5 Å²	18.5	6%	0.056	9%	0.089	C	C	.	.	H	α-helix	trans	-60	-46.9	173.6	-168.3	72.9	175	0	0	111.2	H139 Q212 H250 Y251 F252 L256 I257 Y258	H139-E254 IonicContact CE1-OE1 3.88Å; H139-E254 IonicContact CE1-OE2 3.49Å; H139-E254 PolarHBondContact CE1-OE2 3.17Å; H139-E254 IonicContact NE2-OE1 2.75Å; H139-E254 PolarHBondContact NE2-OE1 3.03Å; H139-E254 VanDerWaalsContact NE2-OE1 3.12Å; H139-E254 IonicContact NE2-OE2 2.7Å; H139-E254 PolarHBondContact NE2-OE2 3.08Å; Q212-E254 PolarHBondContact NE2-OE2 3.45Å; Q212-E254 PolarHBondContact OE1-OE2 2.78Å; H250-E254 PolarHBondContact O-N 2.86Å; H250-E254 VanDerWaalsContact O-N 3.16Å; Y251-E254 PolarHBondContact O-N 3.13Å; F252-E254 VanDerWaalsContact C-N 3.3Å; F252-E254 PolarHBondContact O-N 2.86Å; E254-L256 VanDerWaalsContact C-N 3.3Å; E254-L256 PolarHBondContact O-N 3.22Å; E254-I257 WeakPolarHBondContact O-CB 3.08Å; E254-I257 PolarHBondContact O-N 3.43Å; E254-I257 VanDerWaalsContact O-N 3.15Å; E254-Y258 HydrophobicContact CG-CD2 4.32Å; E254-Y258 HydrophobicContact CG-CE2 4.07Å; E254-Y258 VanDerWaalsContact O-CD2 3.31Å; E254-Y258 WeakPolarHBondContact O-CD2 3.49Å; E254-Y258 PolarHBondContact O-N 3.26Å; E254-Y258 WeakPolarHBondContact OE1-CE2 3.17Å
255	L	98.5	Very high	96.6	Very high	16 Å²	16	16.2 Å²	16.2	8%	0.084	8%	0.079	C	C	.	.	H	α-helix	trans	-56.1	-45.5	175.5	174.1	63.4	0	0	0	111.7	Y251 F252 I257 Y258 V259 V276 V279 L280 F308	Y251-L255 PolarHBondContact O-N 3.24Å; Y251-L255 VanDerWaalsContact O-N 3.08Å; F252-L255 WeakPolarHBondContact O-CB 3.05Å; F252-L255 PolarHBondContact O-N 3.05Å; L255-I257 VanDerWaalsContact C-N 3.32Å; L255-I257 PolarHBondContact O-N 3.09Å; L255-Y258 PolarHBondContact O-N 2.79Å; L255-V259 HydrophobicContact CD1-CG2 4.43Å; L255-V259 WeakPolarHBondContact O-CG2 3.45Å; L255-V259 PolarHBondContact O-N 3.07Å; L255-V276 HydrophobicContact CD1-CG1 4.1Å; L255-V279 HydrophobicContact CD1-CG1 4.39Å; L255-L280 HydrophobicContact CD1-CB 3.9Å; L255-L280 HydrophobicContact CD1-CD1 4.37Å; L255-L280 HydrophobicContact CD2-CD1 3.59Å; L255-F308 HydrophobicContact CD2-CE2 4.07Å; L255-F308 HydrophobicContact CD2-CZ 4.37Å
256	L	98.5	Very high	96.3	Very high	39 Å²	39	13.3 Å²	13.3	20%	0.204	7%	0.065	C	C	.	.	H	α-helix	trans	-63.7	-35.3	178.6	-68	-177.9	0	0	0	112.8	L204 A208 F252 A253 E254 Y258 V259 S260	L204-L256 HydrophobicContact CD1-CB 4.49Å; A208-L256 HydrophobicContact CB-CB 3.61Å; F252-L256 HydrophobicContact CD1-CD1 4.08Å; F252-L256 HydrophobicContact CE1-CD1 3.57Å; F252-L256 HydrophobicContact CE1-CG 4.22Å; F252-L256 HydrophobicContact CE2-CD2 4.36Å; F252-L256 HydrophobicContact CE2-CG 4.34Å; F252-L256 HydrophobicContact CZ-CD1 3.82Å; F252-L256 HydrophobicContact CZ-CD2 4.15Å; F252-L256 HydrophobicContact CZ-CG 4.09Å; F252-L256 WeakPolarHBondContact O-CG 3.4Å; F252-L256 PolarHBondContact O-N 2.92Å; A253-L256 PolarHBondContact O-N 3.25Å; E254-L256 VanDerWaalsContact C-N 3.3Å; E254-L256 PolarHBondContact O-N 3.22Å; L256-Y258 VanDerWaalsContact C-N 3.33Å; L256-Y258 PolarHBondContact O-N 3.17Å; L256-V259 PolarHBondContact O-N 3.02Å; L256-S260 VanDerWaalsContact O-CB 3.27Å; L256-S260 WeakPolarHBondContact O-CB 3.13Å; L256-S260 PolarHBondContact O-N 3.41Å
257	I	98.8	Very high	95.9	Very high	0 Å²	0	14 Å²	14	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-60.6	-43	173.2	-70.5	167.2	0	0	0	110.5	F205 A208 A253 E254 L255 S260 L261	F205-I257 HydrophobicContact CD2-CG2 3.96Å; F205-I257 HydrophobicContact CE2-CG2 3.8Å; A208-I257 HydrophobicContact CB-CG1 3.69Å; A253-I257 WeakPolarHBondContact O-CG1 3.48Å; A253-I257 PolarHBondContact O-N 3.28Å; E254-I257 WeakPolarHBondContact O-CB 3.08Å; E254-I257 PolarHBondContact O-N 3.43Å; E254-I257 VanDerWaalsContact O-N 3.15Å; L255-I257 VanDerWaalsContact C-N 3.32Å; L255-I257 PolarHBondContact O-N 3.09Å; I257-S260 PolarHBondContact O-N 3.44Å; I257-S260 PolarHBondContact O-OG 3.28Å; I257-L261 HydrophobicContact CG2-CD1 4.48Å; I257-L261 VanDerWaalsContact O-CG 3.3Å; I257-L261 WeakPolarHBondContact O-CG 3.45Å; I257-L261 PolarHBondContact O-N 3.37Å; I257-L261 VanDerWaalsContact O-N 3.09Å
258	Y	98.5	Very high	95.5	Very high	2 Å²	2	22.4 Å²	22.4	1%	0.008	11%	0.109	C	C	.	.	H	α-helix	trans	-71.5	-37.2	179.4	-80	-105.7	0	0	0	112.6	Y169 L173 E254 L255 L256 S260 L261 G262 W272 V275 V279	Y169-Y258 WeakPolarHBondContact OH-CE1 3.36Å; Y169-Y258 PolarHBondContact OH-OH 3.38Å; L173-Y258 HydrophobicContact CD1-CE1 3.87Å; L173-Y258 HydrophobicContact CD2-CE1 3.95Å; L173-Y258 WeakPolarHBondContact CD2-OH 3.47Å; E254-Y258 HydrophobicContact CG-CD2 4.32Å; E254-Y258 HydrophobicContact CG-CE2 4.07Å; E254-Y258 VanDerWaalsContact O-CD2 3.31Å; E254-Y258 WeakPolarHBondContact O-CD2 3.49Å; E254-Y258 PolarHBondContact O-N 3.26Å; E254-Y258 WeakPolarHBondContact OE1-CE2 3.17Å; L255-Y258 PolarHBondContact O-N 2.79Å; L256-Y258 VanDerWaalsContact C-N 3.33Å; L256-Y258 PolarHBondContact O-N 3.17Å; Y258-S260 VanDerWaalsContact C-N 3.3Å; Y258-S260 PolarHBondContact O-N 3.5Å; Y258-L261 PolarHBondContact O-N 3.38Å; Y258-G262 PolarHBondContact O-N 2.9Å; Y258-G262 VanDerWaalsContact O-N 3.13Å; Y258-W272 HydrophobicContact CD1-CZ2 4.14Å; Y258-W272 PolarHBondContact O-NE1 2.89Å; Y258-V275 HydrophobicContact CD1-CG1 3.73Å; Y258-V275 HydrophobicContact CE1-CG1 3.85Å; Y258-V279 HydrophobicContact CD1-CG2 3.67Å; Y258-V279 HydrophobicContact CD2-CG1 4.19Å; Y258-V279 HydrophobicContact CD2-CG2 4.14Å; Y258-V279 HydrophobicContact CE1-CG2 3.79Å; Y258-V279 HydrophobicContact CE2-CG2 4.27Å; Y258-V279 HydrophobicContact CG-CB 4.4Å; Y258-V279 HydrophobicContact CG-CG1 4.32Å; Y258-V279 HydrophobicContact CG-CG2 3.83Å
259	V	98.4	Very high	95.2	Very high	27 Å²	27	23.2 Å²	23.2	16%	0.164	12%	0.115	C	C	.	.	H	α-helix	trans	-59.6	-43.6	171.4	171.1	0	0	0	0	110.5	L204 L255 L256 L261 G262 F263 W273 V276	L204-V259 HydrophobicContact CD2-CG1 4.13Å; L255-V259 HydrophobicContact CD1-CG2 4.43Å; L255-V259 WeakPolarHBondContact O-CG2 3.45Å; L255-V259 PolarHBondContact O-N 3.07Å; L256-V259 PolarHBondContact O-N 3.02Å; V259-L261 VanDerWaalsContact C-N 3.34Å; V259-L261 PolarHBondContact O-N 3.4Å; V259-G262 WeakPolarHBondContact O-CA 3.13Å; V259-G262 PolarHBondContact O-N 3.37Å; V259-F263 HydrophobicContact CG1-CD2 4.33Å; V259-F263 HydrophobicContact CG1-CE2 3.83Å; V259-F263 HydrophobicContact CG1-CZ 3.96Å; V259-F263 PolarHBondContact O-N 2.86Å; V259-W273 HydrophobicContact CG1-CH2 4.21Å; V259-W273 HydrophobicContact CG1-CZ3 4.39Å; V259-W273 HydrophobicContact CG2-CZ3 4.37Å; V259-V276 HydrophobicContact CG2-CG1 3.71Å
260	S	98.3	Very high	94.9	Very high	0 Å²	0	28.6 Å²	28.6	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-65.2	-37.8	-178.3	85.9	0	0	0	0	112.5	G201 F205 L256 I257 Y258 G262 F263 T264	G201-S260 WeakPolarHBondContact CA-O 3.44Å; G201-S260 VanDerWaalsContact O-CB 3.25Å; G201-S260 WeakPolarHBondContact O-CB 3.2Å; F205-S260 VanDerWaalsContact CA-OG 3.28Å; F205-S260 WeakPolarHBondContact CA-OG 3.25Å; F205-S260 VanDerWaalsContact CB-OG 3.24Å; F205-S260 WeakPolarHBondContact CB-OG 3.47Å; L256-S260 VanDerWaalsContact O-CB 3.27Å; L256-S260 WeakPolarHBondContact O-CB 3.13Å; L256-S260 PolarHBondContact O-N 3.41Å; I257-S260 PolarHBondContact O-N 3.44Å; I257-S260 PolarHBondContact O-OG 3.28Å; Y258-S260 VanDerWaalsContact C-N 3.3Å; Y258-S260 PolarHBondContact O-N 3.5Å; S260-G262 VanDerWaalsContact C-N 3.3Å; S260-G262 PolarHBondContact O-N 2.86Å; S260-F263 PolarHBondContact O-N 2.79Å; S260-T264 PolarHBondContact O-N 2.91Å; S260-T264 PolarHBondContact O-OG1 2.74Å
261	L	97.3	Very high	94.8	Very high	0 Å²	0	27.8 Å²	27.8	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-64.7	-35.7	171.9	-65.2	176.5	0	0	0	111.6	V132 L135 L136 F205 I257 Y258 V259 T264 L265 W272	V132-L261 HydrophobicContact CG1-CB 4.32Å; V132-L261 HydrophobicContact CG1-CD2 4.22Å; L135-L261 HydrophobicContact CB-CD2 3.55Å; L135-L261 HydrophobicContact CD1-CD2 3.8Å; L135-L261 HydrophobicContact CG-CD2 4.35Å; L136-L261 HydrophobicContact CD2-CD1 3.49Å; L136-L261 VanDerWaalsContact CD2-CD1 3.49Å; L136-L261 HydrophobicContact CG-CD1 3.94Å; F205-L261 HydrophobicContact CD2-CD2 4.07Å; F205-L261 HydrophobicContact CD2-CG 4.49Å; F205-L261 HydrophobicContact CE2-CD2 4.22Å; I257-L261 HydrophobicContact CG2-CD1 4.48Å; I257-L261 VanDerWaalsContact O-CG 3.3Å; I257-L261 WeakPolarHBondContact O-CG 3.45Å; I257-L261 PolarHBondContact O-N 3.37Å; I257-L261 VanDerWaalsContact O-N 3.09Å; Y258-L261 PolarHBondContact O-N 3.38Å; V259-L261 VanDerWaalsContact C-N 3.34Å; V259-L261 PolarHBondContact O-N 3.4Å; L261-T264 CarbonylContact O-C 3.42Å; L261-T264 WeakPolarHBondContact O-CB 3.4Å; L261-T264 PolarHBondContact O-N 3.29Å; L261-T264 VanDerWaalsContact O-N 3.15Å; L261-L265 PolarHBondContact O-N 3.43Å; L261-W272 HydrophobicContact CB-CH2 4.4Å; L261-W272 HydrophobicContact CB-CZ2 3.41Å; L261-W272 VanDerWaalsContact CB-CZ2 3.41Å; L261-W272 HydrophobicContact CD1-CH2 4.1Å; L261-W272 HydrophobicContact CD1-CZ2 3.63Å; L261-W272 HydrophobicContact CG-CZ2 4.17Å
262	G	95.4	Very high	94.7	Very high	1 Å²	1	26 Å²	26	1%	0.01	13%	0.128	C	C	.	.	H	α-helix	trans	-63.3	-42.2	174.9	0	0	0	0	0	112.7	Y258 V259 S260 T264 L265 G267	Y258-G262 PolarHBondContact O-N 2.9Å; Y258-G262 VanDerWaalsContact O-N 3.13Å; V259-G262 WeakPolarHBondContact O-CA 3.13Å; V259-G262 PolarHBondContact O-N 3.37Å; S260-G262 VanDerWaalsContact C-N 3.3Å; S260-G262 PolarHBondContact O-N 2.86Å; G262-T264 VanDerWaalsContact C-N 3.34Å; G262-L265 PolarHBondContact O-N 2.87Å; G262-G267 WeakPolarHBondContact O-CA 3.5Å; G262-G267 PolarHBondContact O-N 3.31Å
263	F	94.7	Very high	94.6	Very high	67 Å²	67	28.6 Å²	28.6	29%	0.294	14%	0.137	S	C	.	.	H	α-helix	trans	-66.2	-35.4	171.7	-66.1	-20.7	0	0	0	112.5	I197 L204 V259 S260 L265 G266 W273	I197-F263 HydrophobicContact CG2-CB 3.9Å; I197-F263 HydrophobicContact CG2-CD1 4.18Å; I197-F263 HydrophobicContact CG2-CG 4.22Å; L204-F263 HydrophobicContact CD2-CD2 4.33Å; L204-F263 HydrophobicContact CD2-CE2 4.3Å; V259-F263 HydrophobicContact CG1-CD2 4.33Å; V259-F263 HydrophobicContact CG1-CE2 3.83Å; V259-F263 HydrophobicContact CG1-CZ 3.96Å; V259-F263 PolarHBondContact O-N 2.86Å; S260-F263 PolarHBondContact O-N 2.79Å; F263-L265 VanDerWaalsContact C-N 3.27Å; F263-L265 PolarHBondContact O-N 2.79Å; F263-G266 WeakPolarHBondContact O-CA 3.47Å; F263-G266 PolarHBondContact O-N 2.75Å; F263-W273 HydrophobicContact CD1-CH2 4.08Å; F263-W273 AromaticContact CD1-CZ2 3.97Å; F263-W273 HydrophobicContact CD1-CZ2 3.97Å; F263-W273 AromaticContact CE1-CH2 3.6Å; F263-W273 HydrophobicContact CE1-CH2 3.6Å; F263-W273 AromaticContact CE1-CZ2 3.71Å; F263-W273 HydrophobicContact CE1-CZ2 3.71Å; F263-W273 HydrophobicContact CZ-CH2 4.27Å
264	T	93.4	Very high	94.6	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-66.8	-29.3	175.1	-50	0	0	0	0	112.2	S128 L131 V132 L135 R198 S260 L261 G262 G266	S128-T264 WeakPolarHBondContact CB-O 3.4Å; L131-T264 HydrophobicContact CB-CG2 4.49Å; L131-T264 HydrophobicContact CD2-CG2 3.51Å; L131-T264 HydrophobicContact CG-CG2 3.81Å; V132-T264 HydrophobicContact CG2-CG2 3.68Å; L135-T264 HydrophobicContact CD1-CG2 4.02Å; R198-T264 WeakPolarHBondContact CG-O 3.29Å; S260-T264 PolarHBondContact O-N 2.91Å; S260-T264 PolarHBondContact O-OG1 2.74Å; L261-T264 CarbonylContact O-C 3.42Å; L261-T264 WeakPolarHBondContact O-CB 3.4Å; L261-T264 PolarHBondContact O-N 3.29Å; L261-T264 VanDerWaalsContact O-N 3.15Å; G262-T264 VanDerWaalsContact C-N 3.34Å; T264-G266 PolarHBondContact O-N 3.49Å
265	L	90.7	Very high	94.6	Very high	24 Å²	24	28.6 Å²	28.6	13%	0.126	14%	0.137	C	C	.	.	T	Hydrogen-bonded Turn	trans	-75.6	4.9	167.8	-69.1	172.7	0	0	0	113.6	V132 L261 G262 F263 W272	V132-L265 HydrophobicContact CB-CD2 4.08Å; V132-L265 HydrophobicContact CB-CG 4.38Å; V132-L265 HydrophobicContact CG1-CD2 4.35Å; V132-L265 HydrophobicContact CG1-CG 4.35Å; V132-L265 HydrophobicContact CG2-CD2 3.71Å; V132-L265 HydrophobicContact CG2-CG 3.7Å; L261-L265 PolarHBondContact O-N 3.43Å; G262-L265 PolarHBondContact O-N 2.87Å; F263-L265 VanDerWaalsContact C-N 3.27Å; F263-L265 PolarHBondContact O-N 2.79Å; L265-W272 HydrophobicContact CD1-CB 3.82Å; L265-W272 HydrophobicContact CD1-CD2 3.61Å; L265-W272 HydrophobicContact CD1-CE3 3.86Å; L265-W272 HydrophobicContact CD1-CG 3.59Å
266	G	87.7	Confident	94.6	Very high	5 Å²	5	28.4 Å²	28.4	5%	0.052	14%	0.137	C	C	.	.	T	Hydrogen-bonded Turn	trans	92.1	0.9	-179.7	0	0	0	0	0	114.7	F263 T264 F268	F263-G266 WeakPolarHBondContact O-CA 3.47Å; F263-G266 PolarHBondContact O-N 2.75Å; T264-G266 PolarHBondContact O-N 3.49Å; G266-F268 VanDerWaalsContact C-N 3.35Å; G266-F268 WeakPolarHBondContact O-CD2 3.3Å; G266-F268 VanDerWaalsContact O-CE2 3.32Å; G266-F268 WeakPolarHBondContact O-CE2 3.48Å; G266-F268 PolarHBondContact O-N 3.44Å
267	G	87.9	Confident	94.6	Very high	14 Å²	14	29.4 Å²	29.4	14%	0.144	14%	0.142	C	C	.	.	S	Bend	trans	83.5	-3.3	170.8	0	0	0	0	0	116.2	G262 W273	G262-G267 WeakPolarHBondContact O-CA 3.5Å; G262-G267 PolarHBondContact O-N 3.31Å; G267-W273 PolarHBondContact O-NE1 3.27Å
268	F	86.1	Confident	94.5	Very high	176 Å²	176	29.7 Å²	29.7	77%	0.772	14%	0.143	S	C	*	.			trans	-115	1.9	-175.3	-57.5	-72.5	0	0	0	114.5	G266 F270	G266-F268 VanDerWaalsContact C-N 3.35Å; G266-F268 WeakPolarHBondContact O-CD2 3.3Å; G266-F268 VanDerWaalsContact O-CE2 3.32Å; G266-F268 WeakPolarHBondContact O-CE2 3.48Å; G266-F268 PolarHBondContact O-N 3.44Å; F268-F270 PolarHBondContact O-N 3.13Å
269	S	89.1	Confident	94.5	Very high	18 Å²	18	29.8 Å²	29.8	13%	0.126	14%	0.143	C	C	.	.			trans	-68.9	103.1	177	176.2	0	0	0	0	110.6	T271 W272 W273	S269-T271 PolarHBondContact O-N 3.22Å; S269-W272 PolarHBondContact O-N 2.99Å; S269-W272 WeakPolarHBondContact OG-CB 3.2Å; S269-W272 PolarHBondContact OG-N 3.37Å; S269-W273 PolarHBondContact O-N 3.11Å
270	F	91.8	Very high	94.5	Very high	113 Å²	113	30.8 Å²	30.8	50%	0.496	15%	0.148	S	C	.	.	H	α-helix	trans	-57.9	-47.7	178.6	177.2	-102.8	0	0	0	111.6	L2 D6 F268 W272 W273 L274	L2-F270 HydrophobicContact CD2-CE1 3.52Å; L2-F270 HydrophobicContact CD2-CZ 4.03Å; D6-F270 HydrophobicContact CB-CE1 4.37Å; F268-F270 PolarHBondContact O-N 3.13Å; F270-W272 VanDerWaalsContact C-N 3.27Å; F270-W272 PolarHBondContact O-N 3.45Å; F270-W273 PolarHBondContact O-N 3.26Å; F270-W273 VanDerWaalsContact O-N 3.14Å; F270-L274 HydrophobicContact CD1-CD1 4.16Å; F270-L274 HydrophobicContact CE1-CD1 3.6Å; F270-L274 HydrophobicContact CE1-CD2 4.5Å; F270-L274 HydrophobicContact CE1-CG 4.14Å; F270-L274 HydrophobicContact CZ-CD1 4.05Å; F270-L274 HydrophobicContact CZ-CD2 4.13Å; F270-L274 HydrophobicContact CZ-CG 4.22Å; F270-L274 PolarHBondContact O-N 3.44Å; F270-L274 VanDerWaalsContact O-N 3.11Å
271	T	93.7	Very high	94.4	Very high	3 Å²	3	32.5 Å²	32.5	2%	0.018	16%	0.155	C	C	.	.	H	α-helix	trans	-55.8	-43.5	177	-47.2	0	0	0	0	111.3	I5 D6 T176 S269 L274 V275	I5-T271 HydrophobicContact CG1-CG2 4.07Å; I5-T271 HydrophobicContact CG2-CG2 3.9Å; D6-T271 WeakPolarHBondContact OD1-CA 3.44Å; D6-T271 WeakPolarHBondContact OD1-CB 3.47Å; D6-T271 WeakPolarHBondContact OD1-CG2 3.49Å; D6-T271 PolarHBondContact OD1-OG1 2.98Å; T176-T271 HydrophobicContact CG2-CG2 3.75Å; S269-T271 PolarHBondContact O-N 3.22Å; T271-L274 WeakPolarHBondContact O-CB 3.43Å; T271-L274 PolarHBondContact O-N 3.4Å; T271-V275 PolarHBondContact O-N 2.79Å
272	W	95.8	Very high	94.4	Very high	0 Å²	0	34.3 Å²	34.3	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-67.7	-37.2	179.5	-167.4	-93.4	0	0	0	112.8	V132 L136 L173 T176 V177 Y258 L261 L265 S269 F270 L274 V275 V276	V132-W272 HydrophobicContact CG1-CH2 4.48Å; L136-W272 HydrophobicContact CD1-CH2 4.33Å; L173-W272 HydrophobicContact CD1-CH2 3.85Å; L173-W272 HydrophobicContact CD1-CZ3 3.96Å; T176-W272 HydrophobicContact CG2-CE3 4.4Å; V177-W272 HydrophobicContact CG2-CE3 4.3Å; V177-W272 HydrophobicContact CG2-CH2 3.93Å; V177-W272 HydrophobicContact CG2-CZ3 3.42Å; V177-W272 VanDerWaalsContact CG2-CZ3 3.42Å; Y258-W272 HydrophobicContact CD1-CZ2 4.14Å; Y258-W272 PolarHBondContact O-NE1 2.89Å; L261-W272 HydrophobicContact CB-CH2 4.4Å; L261-W272 HydrophobicContact CB-CZ2 3.41Å; L261-W272 VanDerWaalsContact CB-CZ2 3.41Å; L261-W272 HydrophobicContact CD1-CH2 4.1Å; L261-W272 HydrophobicContact CD1-CZ2 3.63Å; L261-W272 HydrophobicContact CG-CZ2 4.17Å; L265-W272 HydrophobicContact CD1-CB 3.82Å; L265-W272 HydrophobicContact CD1-CD2 3.61Å; L265-W272 HydrophobicContact CD1-CE3 3.86Å; L265-W272 HydrophobicContact CD1-CG 3.59Å; S269-W272 PolarHBondContact O-N 2.99Å; S269-W272 WeakPolarHBondContact OG-CB 3.2Å; S269-W272 PolarHBondContact OG-N 3.37Å; F270-W272 VanDerWaalsContact C-N 3.27Å; F270-W272 PolarHBondContact O-N 3.45Å; W272-L274 PolarHBondContact O-N 3.24Å; W272-V275 HydrophobicContact CE3-CG2 4.26Å; W272-V275 WeakPolarHBondContact O-CA 3.31Å; W272-V275 VanDerWaalsContact O-CB 3.23Å; W272-V275 WeakPolarHBondContact O-CB 3.39Å; W272-V275 PolarHBondContact O-N 3.23Å; W272-V276 PolarHBondContact O-N 2.98Å
273	W	96.3	Very high	94.4	Very high	83 Å²	83	35.4 Å²	35.4	31%	0.314	17%	0.17	S	C	.	.	H	α-helix	trans	-65.4	-27.8	174.2	-73.2	117.7	0	0	0	112.9	V259 F263 G267 S269 F270 V276 L277	V259-W273 HydrophobicContact CG1-CH2 4.21Å; V259-W273 HydrophobicContact CG1-CZ3 4.39Å; V259-W273 HydrophobicContact CG2-CZ3 4.37Å; F263-W273 HydrophobicContact CD1-CH2 4.08Å; F263-W273 AromaticContact CD1-CZ2 3.97Å; F263-W273 HydrophobicContact CD1-CZ2 3.97Å; F263-W273 AromaticContact CE1-CH2 3.6Å; F263-W273 HydrophobicContact CE1-CH2 3.6Å; F263-W273 AromaticContact CE1-CZ2 3.71Å; F263-W273 HydrophobicContact CE1-CZ2 3.71Å; F263-W273 HydrophobicContact CZ-CH2 4.27Å; G267-W273 PolarHBondContact O-NE1 3.27Å; S269-W273 PolarHBondContact O-N 3.11Å; F270-W273 PolarHBondContact O-N 3.26Å; F270-W273 VanDerWaalsContact O-N 3.14Å; W273-V276 HydrophobicContact CE3-CB 3.88Å; W273-V276 HydrophobicContact CE3-CG1 3.99Å; W273-V276 HydrophobicContact CE3-CG2 3.82Å; W273-V276 HydrophobicContact CZ3-CB 4.33Å; W273-V276 HydrophobicContact CZ3-CG1 4.04Å; W273-V276 HydrophobicContact CZ3-CG2 4.08Å; W273-V276 PolarHBondContact O-N 3.14Å; W273-L277 WeakPolarHBondContact O-CB 3.3Å; W273-L277 PolarHBondContact O-N 3.14Å
274	L	97.4	Very high	94.5	Very high	12 Å²	12	32.4 Å²	32.4	6%	0.063	16%	0.157	C	C	.	.	H	α-helix	trans	-66.7	-36.4	168	-62.1	176.6	0	0	0	112	D6 W9 L10 F270 T271 W272 L277 Y278	D6-L274 HydrophobicContact CB-CD1 3.81Å; D6-L274 WeakPolarHBondContact O-CD1 3.35Å; W9-L274 HydrophobicContact CB-CB 3.68Å; L10-L274 HydrophobicContact CB-CD1 4.29Å; L10-L274 HydrophobicContact CB-CD2 4.3Å; L10-L274 HydrophobicContact CD1-CD2 4.12Å; F270-L274 HydrophobicContact CD1-CD1 4.16Å; F270-L274 HydrophobicContact CE1-CD1 3.6Å; F270-L274 HydrophobicContact CE1-CD2 4.5Å; F270-L274 HydrophobicContact CE1-CG 4.14Å; F270-L274 HydrophobicContact CZ-CD1 4.05Å; F270-L274 HydrophobicContact CZ-CD2 4.13Å; F270-L274 HydrophobicContact CZ-CG 4.22Å; F270-L274 PolarHBondContact O-N 3.44Å; F270-L274 VanDerWaalsContact O-N 3.11Å; T271-L274 WeakPolarHBondContact O-CB 3.43Å; T271-L274 PolarHBondContact O-N 3.4Å; W272-L274 PolarHBondContact O-N 3.24Å; L274-L277 PolarHBondContact O-N 3.19Å; L274-Y278 WeakPolarHBondContact O-CB 3.35Å; L274-Y278 PolarHBondContact O-N 2.66Å
275	V	98	Very high	94.5	Very high	0 Å²	0	32.6 Å²	32.6	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-61.3	-47	170.7	-174.1	0	0	0	0	110.5	W9 L173 T176 Y258 T271 W272 L277 Y278 V279	W9-V275 HydrophobicContact CD2-CG2 3.82Å; W9-V275 HydrophobicContact CE3-CG2 4.42Å; W9-V275 HydrophobicContact CG-CG2 4.04Å; W9-V275 HydrophobicContact CH2-CG1 4.48Å; W9-V275 HydrophobicContact CZ2-CG2 4.07Å; L173-V275 HydrophobicContact CD1-CG1 3.74Å; T176-V275 HydrophobicContact CG2-CG2 3.89Å; Y258-V275 HydrophobicContact CD1-CG1 3.73Å; Y258-V275 HydrophobicContact CE1-CG1 3.85Å; T271-V275 PolarHBondContact O-N 2.79Å; W272-V275 HydrophobicContact CE3-CG2 4.26Å; W272-V275 WeakPolarHBondContact O-CA 3.31Å; W272-V275 VanDerWaalsContact O-CB 3.23Å; W272-V275 WeakPolarHBondContact O-CB 3.39Å; W272-V275 PolarHBondContact O-N 3.23Å; V275-L277 VanDerWaalsContact C-N 3.3Å; V275-L277 PolarHBondContact O-N 3.2Å; V275-Y278 WeakPolarHBondContact O-CB 3.39Å; V275-Y278 PolarHBondContact O-N 3.28Å; V275-V279 WeakPolarHBondContact O-CG2 3.36Å; V275-V279 PolarHBondContact O-N 2.98Å
276	V	98.4	Very high	94.7	Very high	13 Å²	13	31.8 Å²	31.8	8%	0.079	16%	0.155	C	C	.	.	H	α-helix	trans	-59.1	-43.3	177	174.8	0	0	0	0	110.8	L255 V259 W272 W273 V279 L280	L255-V276 HydrophobicContact CD1-CG1 4.1Å; V259-V276 HydrophobicContact CG2-CG1 3.71Å; W272-V276 PolarHBondContact O-N 2.98Å; W273-V276 HydrophobicContact CE3-CB 3.88Å; W273-V276 HydrophobicContact CE3-CG1 3.99Å; W273-V276 HydrophobicContact CE3-CG2 3.82Å; W273-V276 HydrophobicContact CZ3-CB 4.33Å; W273-V276 HydrophobicContact CZ3-CG1 4.04Å; W273-V276 HydrophobicContact CZ3-CG2 4.08Å; W273-V276 PolarHBondContact O-N 3.14Å; V276-V279 PolarHBondContact O-N 2.78Å; V276-L280 WeakPolarHBondContact O-CB 3.34Å; V276-L280 PolarHBondContact O-N 2.74Å
277	L	98.3	Very high	95	Very high	59 Å²	59	31.6 Å²	31.6	31%	0.309	15%	0.153	S	C	.	.	H	α-helix	trans	-63.3	-42.4	177.8	-172.3	65.7	0	0	0	111.9	A13 W273 L274 V275 L280 F281	A13-L277 HydrophobicContact CB-CB 4.4Å; A13-L277 HydrophobicContact CB-CD2 4.12Å; A13-L277 HydrophobicContact CB-CG 4.03Å; W273-L277 WeakPolarHBondContact O-CB 3.3Å; W273-L277 PolarHBondContact O-N 3.14Å; L274-L277 PolarHBondContact O-N 3.19Å; V275-L277 VanDerWaalsContact C-N 3.3Å; V275-L277 PolarHBondContact O-N 3.2Å; L277-L280 HydrophobicContact CD1-CD2 4.35Å; L277-L280 WeakPolarHBondContact O-CB 3.35Å; L277-L280 PolarHBondContact O-N 3.2Å; L277-F281 HydrophobicContact CD1-CD2 4.2Å; L277-F281 HydrophobicContact CD1-CE2 3.43Å; L277-F281 VanDerWaalsContact CD1-CE2 3.43Å; L277-F281 HydrophobicContact CD1-CZ 3.63Å; L277-F281 HydrophobicContact CD2-CE2 4.16Å; L277-F281 HydrophobicContact CG-CD2 4.06Å; L277-F281 HydrophobicContact CG-CE2 3.56Å; L277-F281 HydrophobicContact CG-CZ 4.28Å; L277-F281 WeakPolarHBondContact O-CD2 3.46Å; L277-F281 PolarHBondContact O-N 3.07Å; L277-F281 VanDerWaalsContact O-N 3.12Å
278	Y	98.1	Very high	95.3	Very high	7 Å²	7	32 Å²	32	3%	0.027	15%	0.151	C	C	.	.	H	α-helix	trans	-58.6	-48.8	172	159.3	-97.7	0	0	0	111.5	W9 L12 F16 F165 Y169 L274 V275 L280 F281 N282	W9-Y278 HydrophobicContact CE3-CD1 4.13Å; W9-Y278 HydrophobicContact CE3-CG 4.09Å; W9-Y278 AromaticContact CZ3-CD1 3.7Å; W9-Y278 HydrophobicContact CZ3-CD1 3.7Å; W9-Y278 HydrophobicContact CZ3-CE1 4.1Å; W9-Y278 HydrophobicContact CZ3-CG 4.07Å; L12-Y278 HydrophobicContact CB-CD2 3.65Å; L12-Y278 HydrophobicContact CB-CE2 4.11Å; L12-Y278 HydrophobicContact CB-CG 4.43Å; F16-Y278 HydrophobicContact CD2-CD2 4.06Å; F16-Y278 AromaticContact CD2-CE2 3.62Å; F16-Y278 HydrophobicContact CD2-CE2 3.62Å; F16-Y278 HydrophobicContact CE2-CD2 4.45Å; F16-Y278 AromaticContact CE2-CE2 3.58Å; F16-Y278 HydrophobicContact CE2-CE2 3.58Å; F16-Y278 HydrophobicContact CG-CE2 4.5Å; F16-Y278 HydrophobicContact CZ-CE2 4.42Å; F165-Y278 WeakPolarHBondContact CE1-OH 3.48Å; F165-Y278 HydrophobicContact CZ-CE2 4.23Å; Y169-Y278 AromaticContact CD2-CE1 3.93Å; Y169-Y278 HydrophobicContact CD2-CE1 3.93Å; Y169-Y278 AromaticContact CE2-CD1 3.99Å; Y169-Y278 HydrophobicContact CE2-CD1 3.99Å; Y169-Y278 AromaticContact CE2-CE1 3.33Å; Y169-Y278 HydrophobicContact CE2-CE1 3.33Å; L274-Y278 WeakPolarHBondContact O-CB 3.35Å; L274-Y278 PolarHBondContact O-N 2.66Å; V275-Y278 WeakPolarHBondContact O-CB 3.39Å; V275-Y278 PolarHBondContact O-N 3.28Å; Y278-L280 VanDerWaalsContact C-N 3.32Å; Y278-L280 PolarHBondContact O-N 3.47Å; Y278-F281 PolarHBondContact O-N 2.81Å; Y278-N282 HydrophobicContact CE2-CB 4.29Å; Y278-N282 VanDerWaalsContact O-CB 3.32Å; Y278-N282 WeakPolarHBondContact O-CB 3.43Å; Y278-N282 PolarHBondContact O-N 2.92Å
279	V	98	Very high	95.5	Very high	3 Å²	3	23.9 Å²	23.9	2%	0.018	12%	0.116	C	C	.	.	H	α-helix	trans	-61.4	-43.1	178.8	172.4	0	0	0	0	110.4	L255 Y258 V275 V276 F281 N282 Q283	L255-V279 HydrophobicContact CD1-CG1 4.39Å; Y258-V279 HydrophobicContact CD1-CG2 3.67Å; Y258-V279 HydrophobicContact CD2-CG1 4.19Å; Y258-V279 HydrophobicContact CD2-CG2 4.14Å; Y258-V279 HydrophobicContact CE1-CG2 3.79Å; Y258-V279 HydrophobicContact CE2-CG2 4.27Å; Y258-V279 HydrophobicContact CG-CB 4.4Å; Y258-V279 HydrophobicContact CG-CG1 4.32Å; Y258-V279 HydrophobicContact CG-CG2 3.83Å; V275-V279 WeakPolarHBondContact O-CG2 3.36Å; V275-V279 PolarHBondContact O-N 2.98Å; V276-V279 PolarHBondContact O-N 2.78Å; V279-F281 PolarHBondContact O-N 3.34Å; V279-N282 PolarHBondContact O-N 2.97Å; V279-Q283 HydrophobicContact CG1-CG 3.92Å; V279-Q283 VanDerWaalsContact O-CB 3.29Å; V279-Q283 WeakPolarHBondContact O-CB 3.46Å; V279-Q283 WeakPolarHBondContact O-CG 3.34Å; V279-Q283 PolarHBondContact O-N 3.07Å
280	L	98.1	Very high	95.7	Very high	49 Å²	49	23.2 Å²	23.2	26%	0.257	11%	0.111	S	C	.	.	H	α-helix	trans	-53.8	-53.1	176.4	173.7	64.9	0	0	0	111.5	L255 V276 L277 Y278 A284 F308 I309	L255-L280 HydrophobicContact CD1-CB 3.9Å; L255-L280 HydrophobicContact CD1-CD1 4.37Å; L255-L280 HydrophobicContact CD2-CD1 3.59Å; V276-L280 WeakPolarHBondContact O-CB 3.34Å; V276-L280 PolarHBondContact O-N 2.74Å; L277-L280 HydrophobicContact CD1-CD2 4.35Å; L277-L280 WeakPolarHBondContact O-CB 3.35Å; L277-L280 PolarHBondContact O-N 3.2Å; Y278-L280 VanDerWaalsContact C-N 3.32Å; Y278-L280 PolarHBondContact O-N 3.47Å; L280-A284 WeakPolarHBondContact O-CB 3.27Å; L280-A284 PolarHBondContact O-N 2.88Å; L280-F308 HydrophobicContact CD1-CZ 4.07Å; L280-I309 HydrophobicContact CD1-CD1 4.08Å
281	F	97.3	Very high	95.7	Very high	35 Å²	35	19.2 Å²	19.2	15%	0.154	9%	0.094	C	C	.	.	H	α-helix	trans	-72.7	-36.2	-176.9	-63.6	-42.3	0	0	0	113.3	A13 F16 L17 L277 Y278 V279 A284 L285	A13-F281 HydrophobicContact CB-CD2 4.18Å; A13-F281 VanDerWaalsContact O-CD2 3.27Å; A13-F281 WeakPolarHBondContact O-CD2 3.1Å; F16-F281 HydrophobicContact CB-CB 3.83Å; L17-F281 HydrophobicContact CB-CD1 4.26Å; L17-F281 HydrophobicContact CB-CD2 3.76Å; L17-F281 HydrophobicContact CB-CE1 4.42Å; L17-F281 HydrophobicContact CB-CE2 3.88Å; L17-F281 HydrophobicContact CB-CG 3.95Å; L17-F281 HydrophobicContact CB-CZ 4.23Å; L17-F281 HydrophobicContact CD1-CD1 3.97Å; L17-F281 HydrophobicContact CD1-CE1 3.68Å; L17-F281 HydrophobicContact CD1-CE2 4.45Å; L17-F281 HydrophobicContact CD1-CZ 3.93Å; L17-F281 HydrophobicContact CD2-CE2 4.03Å; L17-F281 HydrophobicContact CD2-CZ 3.92Å; L17-F281 HydrophobicContact CG-CE1 4.42Å; L17-F281 HydrophobicContact CG-CE2 4.34Å; L17-F281 HydrophobicContact CG-CZ 4.24Å; L277-F281 HydrophobicContact CD1-CD2 4.2Å; L277-F281 HydrophobicContact CD1-CE2 3.43Å; L277-F281 VanDerWaalsContact CD1-CE2 3.43Å; L277-F281 HydrophobicContact CD1-CZ 3.63Å; L277-F281 HydrophobicContact CD2-CE2 4.16Å; L277-F281 HydrophobicContact CG-CD2 4.06Å; L277-F281 HydrophobicContact CG-CE2 3.56Å; L277-F281 HydrophobicContact CG-CZ 4.28Å; L277-F281 WeakPolarHBondContact O-CD2 3.46Å; L277-F281 PolarHBondContact O-N 3.07Å; L277-F281 VanDerWaalsContact O-N 3.12Å; Y278-F281 PolarHBondContact O-N 2.81Å; V279-F281 PolarHBondContact O-N 3.34Å; F281-A284 PolarHBondContact O-N 3.5Å; F281-L285 WeakPolarHBondContact O-CB 3.46Å; F281-L285 PolarHBondContact O-N 3.3Å
282	N	96.2	Very high	95.6	Very high	39 Å²	39	21.4 Å²	21.4	21%	0.209	11%	0.106	C	C	.	.	H	α-helix	trans	-61.9	-47.3	173.7	-179.1	38.6	0	0	0	111.5	F16 Y278 V279 L285 A286	F16-N282 HydrophobicContact CD1-CB 3.92Å; F16-N282 HydrophobicContact CE1-CB 4.11Å; F16-N282 WeakPolarHBondContact CE1-OD1 3.35Å; F16-N282 HydrophobicContact CG-CB 4.19Å; Y278-N282 HydrophobicContact CE2-CB 4.29Å; Y278-N282 VanDerWaalsContact O-CB 3.32Å; Y278-N282 WeakPolarHBondContact O-CB 3.43Å; Y278-N282 PolarHBondContact O-N 2.92Å; V279-N282 PolarHBondContact O-N 2.97Å; N282-L285 PolarHBondContact O-N 3.5Å; N282-A286 WeakPolarHBondContact O-CB 3.48Å; N282-A286 PolarHBondContact O-N 2.81Å
283	Q	96.6	Very high	95.3	Very high	23 Å²	23	22 Å²	22	11%	0.107	11%	0.108	C	C	.	.	H	α-helix	trans	-69.3	-34.4	177.8	-64.9	-51.8	-17.9	0	0	112.5	V279 G287 F308	V279-Q283 HydrophobicContact CG1-CG 3.92Å; V279-Q283 VanDerWaalsContact O-CB 3.29Å; V279-Q283 WeakPolarHBondContact O-CB 3.46Å; V279-Q283 WeakPolarHBondContact O-CG 3.34Å; V279-Q283 PolarHBondContact O-N 3.07Å; Q283-G287 WeakPolarHBondContact O-CA 3.49Å; Q283-G287 PolarHBondContact O-N 2.72Å; Q283-F308 HydrophobicContact CB-CE2 4.11Å; Q283-F308 HydrophobicContact CB-CZ 4.28Å
284	A	95.6	Very high	95.1	Very high	4 Å²	4	18.2 Å²	18.2	3%	0.033	9%	0.094	C	C	.	.	H	α-helix	trans	-61.5	-46.6	173	0	0	0	0	0	112.1	F20 L280 F281 Q288 F308 L313	F20-A284 HydrophobicContact CD2-CB 4.25Å; F20-A284 HydrophobicContact CE2-CB 4.19Å; L280-A284 WeakPolarHBondContact O-CB 3.27Å; L280-A284 PolarHBondContact O-N 2.88Å; F281-A284 PolarHBondContact O-N 3.5Å; A284-Q288 VanDerWaalsContact O-CB 3.28Å; A284-Q288 WeakPolarHBondContact O-CB 3.29Å; A284-Q288 PolarHBondContact O-N 3.47Å; A284-F308 HydrophobicContact CB-CE1 3.68Å; A284-F308 HydrophobicContact CB-CZ 4.29Å; A284-L313 HydrophobicContact CB-CD2 3.86Å
285	L	94.6	Very high	94.7	Very high	4 Å²	4	21.4 Å²	21.4	2%	0.021	11%	0.114	C	C	.	.	H	α-helix	trans	-62.1	-50.9	175.8	178.1	61.3	0	0	0	111.8	F16 A19 F20 H23 I46 F281 N282 G287 Q288 L289	F16-L285 HydrophobicContact CD1-CD2 3.85Å; F16-L285 HydrophobicContact CE1-CD2 4.22Å; A19-L285 HydrophobicContact CB-CD2 3.8Å; F20-L285 HydrophobicContact CB-CB 4.38Å; F20-L285 HydrophobicContact CB-CD1 4.49Å; F20-L285 HydrophobicContact CD2-CB 4.45Å; H23-L285 HydrophobicContact CB-CD1 4.15Å; I46-L285 HydrophobicContact CB-CD2 4.13Å; I46-L285 HydrophobicContact CD1-CD1 4.41Å; I46-L285 HydrophobicContact CG2-CD2 4.13Å; F281-L285 WeakPolarHBondContact O-CB 3.46Å; F281-L285 PolarHBondContact O-N 3.3Å; N282-L285 PolarHBondContact O-N 3.5Å; L285-G287 VanDerWaalsContact C-N 3.34Å; L285-G287 PolarHBondContact O-N 3.14Å; L285-Q288 PolarHBondContact O-N 3.3Å; L285-L289 HydrophobicContact CD1-CD1 3.98Å; L285-L289 HydrophobicContact CD1-CG 4.28Å; L285-L289 HydrophobicContact CG-CD1 4.07Å; L285-L289 WeakPolarHBondContact O-CB 3.5Å; L285-L289 VanDerWaalsContact O-CG 3.31Å; L285-L289 WeakPolarHBondContact O-CG 3.37Å; L285-L289 PolarHBondContact O-N 3.49Å
286	A	93.2	Very high	94.3	Very high	8 Å²	8	26 Å²	26	7%	0.066	15%	0.146	C	C	.	.	H	α-helix	trans	-63.3	-40.9	-179.9	0	0	0	0	0	112.3	Y48 Y251 N282 C290	Y48-A286 HydrophobicContact CE1-CB 4.38Å; Y251-A286 HydrophobicContact CD2-CB 4.33Å; Y251-A286 HydrophobicContact CE2-CB 3.8Å; N282-A286 WeakPolarHBondContact O-CB 3.48Å; N282-A286 PolarHBondContact O-N 2.81Å; A286-C290 VanDerWaalsContact O-CB 3.3Å; A286-C290 WeakPolarHBondContact O-CB 3.36Å; A286-C290 PolarHBondContact O-N 3.43Å
287	G	94.3	Very high	93.8	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-63.1	-46.9	176.9	0	0	0	0	0	112.1	Q283 L285 C290 H291	Q283-G287 WeakPolarHBondContact O-CA 3.49Å; Q283-G287 PolarHBondContact O-N 2.72Å; L285-G287 VanDerWaalsContact C-N 3.34Å; L285-G287 PolarHBondContact O-N 3.14Å; G287-C290 WeakPolarHBondContact O-CB 3.39Å; G287-C290 PolarHBondContact O-N 3.38Å; G287-H291 WeakPolarHBondContact O-CB 3.37Å; G287-H291 PolarHBondContact O-N 3.41Å
288	Q	94.1	Very high	93.4	Very high	24 Å²	24	30 Å²	30	11%	0.112	16%	0.159	C	C	.	.	H	α-helix	trans	-63.5	-46.4	178	-172.1	66.4	53.3	0	0	111.9	F20 A284 L285 C290 H291 D292	F20-Q288 HydrophobicContact CD2-CB 4.47Å; F20-Q288 HydrophobicContact CE2-CB 3.92Å; F20-Q288 HydrophobicContact CE2-CG 4.23Å; A284-Q288 VanDerWaalsContact O-CB 3.28Å; A284-Q288 WeakPolarHBondContact O-CB 3.29Å; A284-Q288 PolarHBondContact O-N 3.47Å; L285-Q288 PolarHBondContact O-N 3.3Å; Q288-C290 PolarHBondContact O-N 3.35Å; Q288-H291 WeakPolarHBondContact O-CB 3.38Å; Q288-H291 PolarHBondContact O-N 3.4Å; Q288-H291 VanDerWaalsContact O-N 3.13Å; Q288-D292 PolarHBondContact NE2-OD1 2.99Å; Q288-D292 PolarHBondContact O-N 3.28Å
289	L	91.8	Very high	93	Very high	4 Å²	4	39.3 Å²	39.3	2%	0.021	20%	0.203	C	C	.	.	H	α-helix	trans	-58.8	-36.9	176.4	-73.3	168	0	0	0	112	H23 I46 R47 T51 L285 L293	H23-L289 WeakPolarHBondContact CE1-CD2 3.48Å; I46-L289 HydrophobicContact CB-CD1 4.35Å; I46-L289 HydrophobicContact CD1-CD1 4.28Å; I46-L289 HydrophobicContact CD1-CD2 4.34Å; I46-L289 HydrophobicContact CG1-CD1 4.03Å; R47-L289 HydrophobicContact CG-CD1 4.1Å; R47-L289 HydrophobicContact CG-CD2 3.97Å; T51-L289 HydrophobicContact CG2-CB 4.18Å; L285-L289 HydrophobicContact CD1-CD1 3.98Å; L285-L289 HydrophobicContact CD1-CG 4.28Å; L285-L289 HydrophobicContact CG-CD1 4.07Å; L285-L289 WeakPolarHBondContact O-CB 3.5Å; L285-L289 VanDerWaalsContact O-CG 3.31Å; L285-L289 WeakPolarHBondContact O-CG 3.37Å; L285-L289 PolarHBondContact O-N 3.49Å; L289-L293 WeakPolarHBondContact O-CB 3.29Å; L289-L293 PolarHBondContact O-N 3.06Å
290	C	91.6	Very high	92.6	Very high	4 Å²	4	44.2 Å²	44.2	3%	0.027	24%	0.237	C	C	.	.	H	α-helix	trans	-70.2	-42.7	176.3	-172	0	0	0	0	111.8	K50 C248 A286 G287 Q288 L293 Y294	K50-C290 WeakPolarHBondContact CE-SG 3.26Å; K50-C290 PolarHBondContact NZ-SG 2.93Å; C248-C290 WeakPolarHBondContact SG-CB 3.19Å; C248-C290 PolarHBondContact SG-SG 2.97Å; A286-C290 VanDerWaalsContact O-CB 3.3Å; A286-C290 WeakPolarHBondContact O-CB 3.36Å; A286-C290 PolarHBondContact O-N 3.43Å; G287-C290 WeakPolarHBondContact O-CB 3.39Å; G287-C290 PolarHBondContact O-N 3.38Å; Q288-C290 PolarHBondContact O-N 3.35Å; C290-L293 WeakPolarHBondContact O-CB 3.24Å; C290-L293 PolarHBondContact O-N 2.76Å; C290-Y294 WeakPolarHBondContact O-CD2 2.82Å; C290-Y294 PolarHBondContact O-N 2.83Å; C290-Y294 VanDerWaalsContact O-N 3.07Å; C290-Y294 WeakPolarHBondContact SG-CE2 3.38Å
291	H	93.1	Very high	92.4	Very high	30 Å²	30	42.4 Å²	42.4	14%	0.139	23%	0.227	C	C	.	.	H	α-helix	trans	-61	-50.1	176.1	-175.6	84.7	0	0	0	111.7	S247 G287 Q288 L293 Y294 V295 Y301 R305 A307	S247-H291 PolarHBondContact OG-ND1 3.43Å; G287-H291 WeakPolarHBondContact O-CB 3.37Å; G287-H291 PolarHBondContact O-N 3.41Å; Q288-H291 WeakPolarHBondContact O-CB 3.38Å; Q288-H291 PolarHBondContact O-N 3.4Å; Q288-H291 VanDerWaalsContact O-N 3.13Å; H291-L293 PolarHBondContact O-N 2.89Å; H291-Y294 WeakPolarHBondContact O-CA 3.03Å; H291-Y294 WeakPolarHBondContact O-CB 3.3Å; H291-Y294 PolarHBondContact O-N 2.93Å; H291-V295 WeakPolarHBondContact O-CG2 3.49Å; H291-V295 PolarHBondContact O-N 3.34Å; H291-Y301 AromaticContact CE1-CE1 3.88Å; H291-R305 PolarHBondContact CE1-O 3.39Å; H291-R305 VanDerWaalsContact CE1-O 3.27Å; H291-A307 HydrophobicContact CB-CB 3.78Å
292	D	91.2	Very high	92.1	Very high	49 Å²	49	42.3 Å²	42.3	26%	0.262	23%	0.23	S	C	.	.	H	α-helix	trans	-59.6	-35.4	178.2	-63.6	-14.3	0	0	0	111.8	H23 Q288 S296	H23-D292 IonicContact CD2-OD2 3.41Å; H23-D292 IonicContact CE1-OD2 3.81Å; H23-D292 IonicContact NE2-OD2 3.43Å; H23-D292 PolarHBondContact NE2-OD2 3.19Å; Q288-D292 PolarHBondContact NE2-OD1 2.99Å; Q288-D292 PolarHBondContact O-N 3.28Å; D292-S296 VanDerWaalsContact O-CB 3.29Å; D292-S296 WeakPolarHBondContact O-CB 3.11Å; D292-S296 PolarHBondContact O-N 3.35Å; D292-S296 PolarHBondContact O-OG 3.4Å
293	L	89.3	Confident	91.8	Very high	11 Å²	11	49.9 Å²	49.9	6%	0.058	26%	0.261	C	S	.	.	H	α-helix	trans	-66.3	-41.4	174.1	179.1	67.4	0	0	0	111.6	K50 T51 T54 L289 C290 H291 S296 K297	K50-L293 HydrophobicContact CB-CD2 4Å; K50-L293 HydrophobicContact CD-CD2 3.76Å; K50-L293 HydrophobicContact CG-CD2 3.74Å; T51-L293 HydrophobicContact CG2-CB 4.38Å; T51-L293 HydrophobicContact CG2-CD2 3.95Å; T54-L293 HydrophobicContact CG2-CD1 3.71Å; L289-L293 WeakPolarHBondContact O-CB 3.29Å; L289-L293 PolarHBondContact O-N 3.06Å; C290-L293 WeakPolarHBondContact O-CB 3.24Å; C290-L293 PolarHBondContact O-N 2.76Å; H291-L293 PolarHBondContact O-N 2.89Å; L293-S296 PolarHBondContact O-OG 3.39Å; L293-K297 WeakPolarHBondContact O-CB 3.28Å; L293-K297 PolarHBondContact O-N 3.42Å; L293-K297 VanDerWaalsContact O-N 3.11Å
294	Y	91	Very high	91.5	Very high	4 Å²	4	54.6 Å²	54.6	2%	0.016	28%	0.283	C	S	.	.	H	α-helix	trans	-65.4	-48.5	176.6	-77.5	-63	0	0	0	111.8	K50 H235 V237 P238 C290 H291 S296 K297 Y298 Y301	K50-Y294 VanDerWaalsContact NZ-CZ 3.29Å; K50-Y294 PolarHBondContact NZ-OH 3.33Å; H235-Y294 AromaticContact CE1-CE1 3.08Å; H235-Y294 WeakPolarHBondContact CE1-CE1 3.47Å; H235-Y294 AromaticContact CE1-CZ 3.46Å; H235-Y294 VanDerWaalsContact CE1-CZ 3.46Å; H235-Y294 PolarHBondContact CE1-OH 2.85Å; H235-Y294 VanDerWaalsContact CE1-OH 3.28Å; H235-Y294 AromaticContact NE2-CE1 3.51Å; H235-Y294 AromaticContact NE2-CZ 3.78Å; V237-Y294 HydrophobicContact CG2-CD1 4.19Å; V237-Y294 HydrophobicContact CG2-CE1 4.47Å; P238-Y294 VanDerWaalsContact CD-OH 3.28Å; P238-Y294 WeakPolarHBondContact CD-OH 3.49Å; C290-Y294 WeakPolarHBondContact O-CD2 2.82Å; C290-Y294 PolarHBondContact O-N 2.83Å; C290-Y294 VanDerWaalsContact O-N 3.07Å; C290-Y294 WeakPolarHBondContact SG-CE2 3.38Å; H291-Y294 WeakPolarHBondContact O-CA 3.03Å; H291-Y294 WeakPolarHBondContact O-CB 3.3Å; H291-Y294 PolarHBondContact O-N 2.93Å; Y294-S296 VanDerWaalsContact C-N 3.31Å; Y294-S296 PolarHBondContact O-N 3.47Å; Y294-K297 PolarHBondContact O-N 2.82Å; Y294-Y298 AromaticContact CD1-CD2 3.97Å; Y294-Y298 HydrophobicContact CD1-CD2 3.97Å; Y294-Y298 AromaticContact CD1-CE2 3.84Å; Y294-Y298 HydrophobicContact CD1-CE2 3.84Å; Y294-Y298 HydrophobicContact CE1-CE2 4.38Å; Y294-Y298 WeakPolarHBondContact O-CD2 3.35Å; Y294-Y298 PolarHBondContact O-N 3.42Å; Y294-Y301 VanDerWaalsContact CB-CE2 3.49Å; Y294-Y301 HydrophobicContact CD1-CD2 4.42Å; Y294-Y301 HydrophobicContact CD1-CE2 4.11Å; Y294-Y301 HydrophobicContact CD2-CE2 4.26Å; Y294-Y301 HydrophobicContact CG-CD2 4.25Å; Y294-Y301 AromaticContact CG-CE2 3.74Å; Y294-Y301 HydrophobicContact CG-CE2 3.74Å
295	V	91	Very high	91.4	Very high	79 Å²	79	54.6 Å²	54.6	48%	0.479	28%	0.282	S	S	.	.	H	α-helix	trans	-60.3	-41.3	-179.9	173.2	0	0	0	0	111.5	H291 Y301	H291-V295 WeakPolarHBondContact O-CG2 3.49Å; H291-V295 PolarHBondContact O-N 3.34Å; V295-Y301 HydrophobicContact CG2-CD1 3.76Å; V295-Y301 HydrophobicContact CG2-CE1 4.09Å
296	S	88.7	Confident	91.3	Very high	97 Å²	97	59.7 Å²	59.7	68%	0.678	30%	0.301	S	S	*	.	H	α-helix	trans	-76.9	-25.1	-179.3	61.6	0	0	0	0	113.8	D292 L293 Y294	D292-S296 VanDerWaalsContact O-CB 3.29Å; D292-S296 WeakPolarHBondContact O-CB 3.11Å; D292-S296 PolarHBondContact O-N 3.35Å; D292-S296 PolarHBondContact O-OG 3.4Å; L293-S296 PolarHBondContact O-OG 3.39Å; Y294-S296 VanDerWaalsContact C-N 3.31Å; Y294-S296 PolarHBondContact O-N 3.47Å
297	K	88.7	Confident	91.3	Very high	114 Å²	114	59.3 Å²	59.3	50%	0.496	30%	0.298	S	S	.	.	H	α-helix	trans	-93.9	-31.3	-175	-175.6	171.2	179.2	176.3	0	114.1	L293 Y294	L293-K297 WeakPolarHBondContact O-CB 3.28Å; L293-K297 PolarHBondContact O-N 3.42Å; L293-K297 VanDerWaalsContact O-N 3.11Å; Y294-K297 PolarHBondContact O-N 2.82Å
298	Y	89.6	Confident	91.2	Very high	42 Å²	42	59.3 Å²	59.3	17%	0.165	30%	0.298	C	S	.	.			trans	-122.3	110	-173.3	-56.9	-83.1	0	0	0	110.3	H235 V237 Y294 S300 Y301	H235-Y298 WeakPolarHBondContact CB-OH 3.25Å; H235-Y298 PolarHBondContact O-OH 3.33Å; V237-Y298 HydrophobicContact CG2-CD1 3.81Å; V237-Y298 HydrophobicContact CG2-CD2 3.46Å; V237-Y298 VanDerWaalsContact CG2-CD2 3.46Å; V237-Y298 HydrophobicContact CG2-CE1 4.11Å; V237-Y298 HydrophobicContact CG2-CE2 3.8Å; V237-Y298 HydrophobicContact CG2-CG 3.48Å; V237-Y298 VanDerWaalsContact CG2-CG 3.48Å; Y294-Y298 AromaticContact CD1-CD2 3.97Å; Y294-Y298 HydrophobicContact CD1-CD2 3.97Å; Y294-Y298 AromaticContact CD1-CE2 3.84Å; Y294-Y298 HydrophobicContact CD1-CE2 3.84Å; Y294-Y298 HydrophobicContact CE1-CE2 4.38Å; Y294-Y298 WeakPolarHBondContact O-CD2 3.35Å; Y294-Y298 PolarHBondContact O-N 3.42Å; Y298-S300 PolarHBondContact O-N 3Å; Y298-Y301 WeakPolarHBondContact O-CB 3.48Å; Y298-Y301 PolarHBondContact O-N 3.35Å
299	E	88.9	Confident	91	Very high	203 Å²	203	59.9 Å²	59.9	95%	0.949	30%	0.301	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61	-32	177	-65.6	-176.2	172.9	0	0	112.5	Y301	E299-Y301 PolarHBondContact O-N 3.05Å
300	S	90.1	Very high	90.7	Very high	105 Å²	105	60.5 Å²	60.5	73%	0.734	31%	0.305	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.4	6.8	176.8	62.9	0	0	0	0	114.2	Y298	Y298-S300 PolarHBondContact O-N 3Å
301	Y	92.9	Very high	90.3	Very high	11 Å²	11	68.5 Å²	68.5	4%	0.043	34%	0.34	C	S	.	.			trans	-63.4	131.7	-176.8	-168.3	-105.6	0	0	0	111.9	V237 S247 H291 Y294 V295 Y298 E299 K303 R305	V237-Y301 HydrophobicContact CG1-CD2 3.88Å; V237-Y301 HydrophobicContact CG1-CE2 3.83Å; V237-Y301 HydrophobicContact CG2-CD2 4.15Å; S247-Y301 WeakPolarHBondContact CB-OH 3.33Å; S247-Y301 PolarHBondContact OG-OH 3.26Å; H291-Y301 AromaticContact CE1-CE1 3.88Å; Y294-Y301 VanDerWaalsContact CB-CE2 3.49Å; Y294-Y301 HydrophobicContact CD1-CD2 4.42Å; Y294-Y301 HydrophobicContact CD1-CE2 4.11Å; Y294-Y301 HydrophobicContact CD2-CE2 4.26Å; Y294-Y301 HydrophobicContact CG-CD2 4.25Å; Y294-Y301 AromaticContact CG-CE2 3.74Å; Y294-Y301 HydrophobicContact CG-CE2 3.74Å; V295-Y301 HydrophobicContact CG2-CD1 3.76Å; V295-Y301 HydrophobicContact CG2-CE1 4.09Å; Y298-Y301 WeakPolarHBondContact O-CB 3.48Å; Y298-Y301 PolarHBondContact O-N 3.35Å; E299-Y301 PolarHBondContact O-N 3.05Å; Y301-K303 PolarHBondContact O-N 3.27Å; Y301-K303 VanDerWaalsContact O-N 3.08Å; Y301-R305 HydrophobicContact CE1-CB 4.29Å
302	P	91.3	Very high	89.9	Confident	33 Å²	33	72.4 Å²	72.4	21%	0.214	37%	0.366	C	S	.	.			trans	-64.3	112.8	-177	-24.4	35.5	0	0	0	112.9	H304 R305	P302-H304 PolarHBondContact O-N 3.3Å; P302-R305 HydrophobicContact CB-CG 4.07Å; P302-R305 PolarHBondContact O-N 3.38Å
303	K	89.6	Confident	88.7	Confident	198 Å²	198	72 Å²	72	86%	0.861	36%	0.363	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.8	-19.2	-174.8	-62.4	-175.2	-178.7	178.9	0	114.8	Y301	Y301-K303 PolarHBondContact O-N 3.27Å; Y301-K303 VanDerWaalsContact O-N 3.08Å
304	H	90.4	Very high	88.7	Confident	123 Å²	123	75 Å²	75	57%	0.569	38%	0.379	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.2	-19.6	178.9	66.8	-93.7	0	0	0	112.9	E244 P302	E244-H304 PolarHBondContact O-NE2 3.42Å; E244-H304 VanDerWaalsContact O-NE2 3.14Å; P302-H304 PolarHBondContact O-N 3.3Å
305	R	93.1	Very high	88.6	Confident	3 Å²	3	78.7 Å²	78.7	1%	0.011	40%	0.398	C	S	.	.			trans	-63.6	142.9	179.9	-73.8	178	-172.9	-168.6	5.2	110.4	P238 F243 E244 L245 H291 Y301 P302	P238-R305 PolarHBondContact O-NH1 3.13Å; F243-R305 WeakPolarHBondContact O-CD 3.33Å; F243-R305 PolarHBondContact O-NE 3.41Å; F243-R305 PolarHBondContact O-NH1 2.97Å; E244-R305 WeakPolarHBondContact O-CG 3.27Å; E244-R305 IonicContact OE1-NH2 3.82Å; E244-R305 PolarHBondContact OE1-NH2 3.11Å; E244-R305 VanDerWaalsContact OE1-NH2 3.15Å; E244-R305 IonicContact OE2-CZ 3.89Å; E244-R305 IonicContact OE2-NE 2.93Å; E244-R305 IonicContact OE2-NH2 3.65Å; E244-R305 PolarHBondContact OE2-NH2 3.01Å; L245-R305 WeakPolarHBondContact O-CA 3.42Å; H291-R305 PolarHBondContact CE1-O 3.39Å; H291-R305 VanDerWaalsContact CE1-O 3.27Å; Y301-R305 HydrophobicContact CE1-CB 4.29Å; P302-R305 HydrophobicContact CB-CG 4.07Å; P302-R305 PolarHBondContact O-N 3.38Å
306	R	93.9	Very high	88.4	Confident	111 Å²	111	78.7 Å²	78.7	42%	0.419	39%	0.393	S	S	.	.	B	Isolated β-bridge	trans	-99.3	167.1	172.3	-67.8	-60.6	-177.9	-123.3	0.4	110.6	L245 V246 S247 L313	L245-R306 PolarHBondContact O-N 2.9Å; V246-R306 CarbonylContact C-O 3.57Å; V246-R306 WeakPolarHBondContact CA-O 3.31Å; V246-R306 HydrophobicContact CG1-CB 4.08Å; S247-R306 PolarHBondContact N-O 3.46Å; S247-R306 PolarHBondContact OG-O 3.28Å; R306-L313 WeakPolarHBondContact CB-OXT 3.49Å
307	A	91.9	Very high	88.4	Confident	0 Å²	0	77.6 Å²	77.6	0%	0	38%	0.376	C	S	.	.	S	Bend	trans	-65.5	-53.2	-175.3	0	0	0	0	0	112.2	S247 C248 H291 L313	S247-A307 WeakPolarHBondContact CB-O 3.39Å; S247-A307 PolarHBondContact N-O 3.12Å; C248-A307 PolarHBondContact N-O 3.28Å; H291-A307 HydrophobicContact CB-CB 3.78Å; A307-L313 WeakPolarHBondContact CB-OXT 3.42Å; A307-L313 VanDerWaalsContact N-C 3.29Å; A307-L313 PolarHBondContact N-O 3.43Å; A307-L313 PolarHBondContact N-OXT 3Å
308	F	91.9	Very high	88.4	Confident	0 Å²	0	75.4 Å²	75.4	0%	0	37%	0.369	C	S	.	.	S	Bend	trans	-153.5	-28.6	175.8	93.2	-77.5	0	0	0	116.1	V246 C248 F252 L255 L280 Q283 A284 L313	V246-F308 WeakPolarHBondContact CG1-O 3.29Å; C248-F308 HydrophobicContact CB-CB 4.04Å; F252-F308 HydrophobicContact CB-CD2 3.94Å; F252-F308 VanDerWaalsContact CB-O 3.31Å; F252-F308 WeakPolarHBondContact CB-O 3.4Å; L255-F308 HydrophobicContact CD2-CE2 4.07Å; L255-F308 HydrophobicContact CD2-CZ 4.37Å; L280-F308 HydrophobicContact CD1-CZ 4.07Å; Q283-F308 HydrophobicContact CB-CE2 4.11Å; Q283-F308 HydrophobicContact CB-CZ 4.28Å; A284-F308 HydrophobicContact CB-CE1 3.68Å; A284-F308 HydrophobicContact CB-CZ 4.29Å; F308-L313 CarbonylContact C-O 3.58Å; F308-L313 HydrophobicContact CD1-CD2 4.39Å; F308-L313 HydrophobicContact CE1-CD2 3.97Å; F308-L313 PolarHBondContact N-O 3.39Å
309	I	90.7	Very high	88.3	Confident	37 Å²	37	77.6 Å²	77.6	19%	0.19	38%	0.383	C	S	.	.	S	Bend	trans	-94.1	117	174.6	-56.6	178.3	0	0	0	108.7	F252 L280 F311 V312 L313	F252-I309 HydrophobicContact CD2-CG1 4.33Å; F252-I309 HydrophobicContact CE2-CG2 4.42Å; L280-I309 HydrophobicContact CD1-CD1 4.08Å; I309-F311 PolarHBondContact O-N 3.34Å; I309-V312 HydrophobicContact CB-CB 4.2Å; I309-V312 HydrophobicContact CG2-CB 3.81Å; I309-V312 HydrophobicContact CG2-CG2 4.11Å; I309-V312 PolarHBondContact O-N 3.38Å; I309-L313 HydrophobicContact CB-CB 4.34Å; I309-L313 PolarHBondContact N-O 3.35Å; I309-L313 PolarHBondContact O-N 3.26Å; I309-L313 VanDerWaalsContact O-N 3.08Å
310	P	85.4	Confident	88.3	Confident	16 Å²	16	68.6 Å²	68.6	10%	0.104	34%	0.342	C	S	.	.	T	Hydrogen-bonded Turn	trans	-52.8	134.5	-179.6	-25	33	0	0	0	111.7	W242 V246 V312	W242-P310 HydrophobicContact CE3-CG 4.24Å; W242-P310 HydrophobicContact CZ3-CG 3.89Å; V246-P310 HydrophobicContact CG1-CB 4.27Å; V246-P310 HydrophobicContact CG1-CG 3.95Å; P310-V312 PolarHBondContact O-N 3.27Å
311	F	84	Confident	88.2	Confident	172 Å²	172	65.8 Å²	65.8	75%	0.754	31%	0.312	S	S	*	.	T	Hydrogen-bonded Turn	trans	64.1	-7.3	177.6	-41.1	-71	0	0	0	116.7	L245 I309	L245-F311 HydrophobicContact CD2-CE1 4.49Å; L245-F311 HydrophobicContact CD2-CZ 4.18Å; I309-F311 PolarHBondContact O-N 3.34Å
312	V	84.9	Confident	87.8	Confident	113 Å²	113	70.4 Å²	70.4	69%	0.685	33%	0.334	S	S	*	.	T	Hydrogen-bonded Turn	trans	-113.2	-64.5	-177.1	178.5	0	0	0	0	111.9	I309 P310	I309-V312 HydrophobicContact CB-CB 4.2Å; I309-V312 HydrophobicContact CG2-CB 3.81Å; I309-V312 HydrophobicContact CG2-CG2 4.11Å; I309-V312 PolarHBondContact O-N 3.38Å; P310-V312 PolarHBondContact O-N 3.27Å
313	L	66.1	Low	87.4	Confident	39 Å²	39	73.8 Å²	73.8	20%	0.204	35%	0.345	C	S	.	.			trans	-131.7	0	-170.9	179.5	61	0	0	0	111.6	F20 A284 R306 A307 F308 I309	F20-L313 HydrophobicContact CE2-CD2 4.19Å; F20-L313 HydrophobicContact CZ-CD1 3.93Å; F20-L313 HydrophobicContact CZ-CD2 3.77Å; A284-L313 HydrophobicContact CB-CD2 3.86Å; R306-L313 WeakPolarHBondContact CB-OXT 3.49Å; A307-L313 WeakPolarHBondContact CB-OXT 3.42Å; A307-L313 VanDerWaalsContact N-C 3.29Å; A307-L313 PolarHBondContact N-O 3.43Å; A307-L313 PolarHBondContact N-OXT 3Å; F308-L313 CarbonylContact C-O 3.58Å; F308-L313 HydrophobicContact CD1-CD2 4.39Å; F308-L313 HydrophobicContact CE1-CD2 3.97Å; F308-L313 PolarHBondContact N-O 3.39Å; I309-L313 HydrophobicContact CB-CB 4.34Å; I309-L313 PolarHBondContact N-O 3.35Å; I309-L313 PolarHBondContact O-N 3.26Å; I309-L313 VanDerWaalsContact O-N 3.08Å

Retrieved 313 of 313 residues in 295.4 ms (Link to these results)

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