A0A087YHA9_POEFO Loading...

Large ribosomal subunit protein uL18

AlphaFold DB , UniProt , Accession A0A087YHA9, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 298 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M56.9Low89.2Confident228 Ų228134.3 Ų134.3100%1.12371%0.713SS**  01220-146.4170.9-159.100106.5F3M1-F3 PolarHBondContact O-N 3.16Å
2G77.8Confident89.9Confident73 Ų73129.3 Ų129.375%0.75368%0.678SS**  trans-72.7127.3-179.200000110.8V4G2-V4 PolarHBondContact O-N 3.06Å; G2-V4 VanDerWaalsContact O-N 3.14Å
3F87.1Confident90.5Very high216 Ų216129.5 Ų129.595%0.94767%0.67SS**  trans-76.111.9179.2-63.9-79.7000114.1M1M1-F3 PolarHBondContact O-N 3.16Å
4V91.8Very high91Very high122 Ų122132.4 Ų132.474%0.73968%0.675SS**SBendtrans-98129.8-175.6-176.80000110.6G2 V6G2-V4 PolarHBondContact O-N 3.06Å; G2-V4 VanDerWaalsContact O-N 3.14Å; V4-V6 PolarHBondContact O-N 3.34Å
5K91.8Very high91.4Very high183 Ų183137.1 Ų137.180%0.79668%0.681SS**  trans-59.5124.5175.9-175.6176.1-177.4173.50111V7K5-V7 PolarHBondContact O-N 2.95Å; K5-V7 VanDerWaalsContact O-N 3.13Å
6V93.6Very high91.8Very high103 Ų103136.1 Ų136.162%0.62467%0.668SS**  trans-69.5110.8176.8-177.30000110.3V4V4-V6 PolarHBondContact O-N 3.34Å
7V95.1Very high92.2Very high117 Ų117137.4 Ų137.471%0.70967%0.672SS**SBendtrans-79.1-40.2-177.2-137.10000112.4K5 N9K5-V7 PolarHBondContact O-N 2.95Å; K5-V7 VanDerWaalsContact O-N 3.13Å; V7-N9 VanDerWaalsContact C-N 3.25Å; V7-N9 PolarHBondContact O-N 3.32Å; V7-N9 VanDerWaalsContact O-N 3.07Å
8K96.1Very high92.5Very high153 Ų153134.2 Ų134.267%0.66566%0.662SS**SBendtrans-86.161.9177-67.1-177.8179.6175.60111.1F13K8-F13 HydrophobicContact CB-CE2 4.23Å; K8-F13 HydrophobicContact CB-CZ 4.19Å
9N96.3Very high92.8Very high61 Ų61134 Ų13433%0.32666%0.657SS.*  trans-92.1178.5-177.36614.2000112.8V7 A11 Y12 F13V7-N9 VanDerWaalsContact C-N 3.25Å; V7-N9 PolarHBondContact O-N 3.32Å; V7-N9 VanDerWaalsContact O-N 3.07Å; N9-A11 VanDerWaalsContact C-N 3.25Å; N9-A11 PolarHBondContact O-N 2.89Å; N9-A11 PolarHBondContact OD1-N 3.21Å; N9-Y12 WeakPolarHBondContact O-CB 3.42Å; N9-Y12 PolarHBondContact O-N 3.42Å; N9-Y12 VanDerWaalsContact O-N 3.17Å; N9-Y12 WeakPolarHBondContact OD1-CB 3.49Å; N9-Y12 PolarHBondContact OD1-N 3.34Å; N9-F13 VanDerWaalsContact O-CD2 3.28Å; N9-F13 WeakPolarHBondContact O-CD2 3.38Å; N9-F13 PolarHBondContact O-N 3.15Å
10K97.3Very high93Very high170 Ų170134.5 Ų134.574%0.73966%0.656SS**Hα-helixtrans-57.1-38.2178.1-172.7176-176.8178.30112.5K14K10-K14 WeakPolarHBondContact O-CG 2.99Å; K10-K14 PolarHBondContact O-N 3.3Å; K10-K14 VanDerWaalsContact O-N 3.15Å
11A97.5Very high93.3Very high51 Ų51136.2 Ų136.242%0.42166%0.655SS.*Hα-helixtrans-67-38.8178.600000112.1N9 K14 R15N9-A11 VanDerWaalsContact C-N 3.25Å; N9-A11 PolarHBondContact O-N 2.89Å; N9-A11 PolarHBondContact OD1-N 3.21Å; A11-K14 PolarHBondContact O-N 3.44Å; A11-R15 WeakPolarHBondContact O-CG 3.37Å; A11-R15 PolarHBondContact O-N 2.91Å
12Y97.7Very high95.2Very high75 Ų75130.6 Ų130.629%0.29462%0.621SS.*Hα-helixtrans-56.3-54.3174.6174.7-91.8000111.1N9 K14 R15 Y16N9-Y12 WeakPolarHBondContact O-CB 3.42Å; N9-Y12 PolarHBondContact O-N 3.42Å; N9-Y12 VanDerWaalsContact O-N 3.17Å; N9-Y12 WeakPolarHBondContact OD1-CB 3.49Å; N9-Y12 PolarHBondContact OD1-N 3.34Å; Y12-K14 VanDerWaalsContact C-N 3.31Å; Y12-K14 PolarHBondContact O-N 2.65Å; Y12-R15 CarbonylContact O-C 3.57Å; Y12-R15 PolarHBondContact O-N 3.35Å; Y12-Y16 HydrophobicContact CD1-CD2 4.45Å; Y12-Y16 AromaticContact CE1-CD2 3.6Å; Y12-Y16 HydrophobicContact CE1-CD2 3.6Å; Y12-Y16 HydrophobicContact CE1-CE2 4.09Å; Y12-Y16 HydrophobicContact CE1-CG 4.14Å; Y12-Y16 HydrophobicContact CE2-CD2 4.07Å; Y12-Y16 HydrophobicContact CE2-CE2 4.46Å; Y12-Y16 AromaticContact CZ-CD2 3.39Å; Y12-Y16 AromaticContact CZ-CE2 3.63Å; Y12-Y16 WeakPolarHBondContact O-CB 3.43Å; Y12-Y16 PolarHBondContact O-N 3.47Å; Y12-Y16 WeakPolarHBondContact OH-CD2 3.32Å; Y12-Y16 WeakPolarHBondContact OH-CE2 3.24Å
13F97.7Very high96.2Very high131 Ų131133.4 Ų133.458%0.57561%0.609SS**Hα-helixtrans-67.4-29.9-177.8-66.9-67.3000113.4K8 N9 R15 Y16K8-F13 HydrophobicContact CB-CE2 4.23Å; K8-F13 HydrophobicContact CB-CZ 4.19Å; N9-F13 VanDerWaalsContact O-CD2 3.28Å; N9-F13 WeakPolarHBondContact O-CD2 3.38Å; N9-F13 PolarHBondContact O-N 3.15Å; F13-R15 VanDerWaalsContact C-N 3.26Å; F13-R15 PolarHBondContact O-N 3.46Å; F13-Y16 PolarHBondContact O-N 3.47Å
14K97.2Very high96.7Very high170 Ų170130.1 Ų130.174%0.73959%0.591SS**Hα-helixtrans-62-31.3174.5-83.8-174.4173.1-166.90113.2K10 A11 Y12K10-K14 WeakPolarHBondContact O-CG 2.99Å; K10-K14 PolarHBondContact O-N 3.3Å; K10-K14 VanDerWaalsContact O-N 3.15Å; A11-K14 PolarHBondContact O-N 3.44Å; Y12-K14 VanDerWaalsContact C-N 3.31Å; Y12-K14 PolarHBondContact O-N 2.65Å
15R97.3Very high97Very high204 Ų204128.6 Ų128.677%0.7758%0.575SS**THydrogen-bonded Turntrans-113.211-178.271.7-170.6176.1177.70.1113.6A11 Y12 F13 E17A11-R15 WeakPolarHBondContact O-CG 3.37Å; A11-R15 PolarHBondContact O-N 2.91Å; Y12-R15 CarbonylContact O-C 3.57Å; Y12-R15 PolarHBondContact O-N 3.35Å; F13-R15 VanDerWaalsContact C-N 3.26Å; F13-R15 PolarHBondContact O-N 3.46Å; R15-E17 PolarHBondContact O-N 3.48Å
16Y97.6Very high97.2Very high121 Ų121121.8 Ų121.848%0.47556%0.558SS.*  trans-77.6107.7-176.9-172.3-102.9000110.1Y12 F13 V18Y12-Y16 HydrophobicContact CD1-CD2 4.45Å; Y12-Y16 AromaticContact CE1-CD2 3.6Å; Y12-Y16 HydrophobicContact CE1-CD2 3.6Å; Y12-Y16 HydrophobicContact CE1-CE2 4.09Å; Y12-Y16 HydrophobicContact CE1-CG 4.14Å; Y12-Y16 HydrophobicContact CE2-CD2 4.07Å; Y12-Y16 HydrophobicContact CE2-CE2 4.46Å; Y12-Y16 AromaticContact CZ-CD2 3.39Å; Y12-Y16 AromaticContact CZ-CE2 3.63Å; Y12-Y16 WeakPolarHBondContact O-CB 3.43Å; Y12-Y16 PolarHBondContact O-N 3.47Å; Y12-Y16 WeakPolarHBondContact OH-CD2 3.32Å; Y12-Y16 WeakPolarHBondContact OH-CE2 3.24Å; F13-Y16 PolarHBondContact O-N 3.47Å; Y16-V18 HydrophobicContact CD1-CG1 3.76Å; Y16-V18 HydrophobicContact CE1-CG1 3.81Å; Y16-V18 PolarHBondContact O-N 3.31Å
17E97.9Very high97.4Very high157 Ų157122.3 Ų122.373%0.73455%0.551SS**  trans-82.9113.5173.8-166.2-167.6165.600110.2R15R15-E17 PolarHBondContact O-N 3.48Å
18V97.6Very high97.5Very high80 Ų80117.5 Ų117.549%0.48552%0.522SS..PPolyproline II helixtrans-75.5130.5178.5-63.30000110.4Y16Y16-V18 HydrophobicContact CD1-CG1 3.76Å; Y16-V18 HydrophobicContact CE1-CG1 3.81Å; Y16-V18 PolarHBondContact O-N 3.31Å
19K98.2Very high97.6Very high131 Ų131113 Ų11357%0.5751%0.505SS*.PPolyproline II helixtrans-61.8163.1169-57.4-57.5-178.2-170.90110.9R23 R24K19-R23 HydrophobicContact CB-CB 4.38Å; K19-R23 HydrophobicContact CB-CG 4.17Å; K19-R24 HydrophobicContact CB-CG 4.13Å; K19-R24 VanDerWaalsContact O-CD 3.28Å; K19-R24 WeakPolarHBondContact O-CD 3.46Å; K19-R24 WeakPolarHBondContact O-CG 3.43Å; K19-R24 PolarHBondContact O-NH1 3.09Å
20F98.3Very high97.7Very high143 Ų143113.5 Ų113.563%0.62751%0.505SS*.PPolyproline II helixtrans-52.8145.4177.5-61.8-23.8000112.6R22 R23 R24 F30F20-R22 PolarHBondContact O-N 2.89Å; F20-R23 HydrophobicContact CB-CB 4.44Å; F20-R23 WeakPolarHBondContact O-CA 3.39Å; F20-R23 WeakPolarHBondContact O-CB 3.34Å; F20-R23 PolarHBondContact O-N 2.97Å; F20-R24 PolarHBondContact O-N 3.45Å; F20-F30 HydrophobicContact CB-CD2 4.47Å; F20-F30 HydrophobicContact CB-CE2 3.75Å; F20-F30 HydrophobicContact CB-CZ 3.93Å; F20-F30 AromaticContact CD2-CD1 3.95Å; F20-F30 HydrophobicContact CD2-CD1 3.95Å; F20-F30 AromaticContact CD2-CD2 3.86Å; F20-F30 HydrophobicContact CD2-CD2 3.86Å; F20-F30 AromaticContact CD2-CE1 3.87Å; F20-F30 HydrophobicContact CD2-CE1 3.87Å; F20-F30 AromaticContact CD2-CE2 3.77Å; F20-F30 HydrophobicContact CD2-CE2 3.77Å; F20-F30 AromaticContact CD2-CG 3.94Å; F20-F30 HydrophobicContact CD2-CG 3.94Å; F20-F30 AromaticContact CD2-CZ 3.77Å; F20-F30 HydrophobicContact CD2-CZ 3.77Å; F20-F30 HydrophobicContact CE2-CD1 4.32Å; F20-F30 HydrophobicContact CE2-CE1 4.5Å; F20-F30 HydrophobicContact CE2-CG 4.44Å; F20-F30 HydrophobicContact CG-CE2 4.28Å; F20-F30 HydrophobicContact CG-CZ 4.31Å
21R98.4Very high97.7Very high172 Ų172112.8 Ų112.865%0.64950%0.498SS*.Hα-helixtrans-48.3-51.8-175-176.4-176.768.2-168.9-2.6113R23 R24 E25R21-R23 VanDerWaalsContact C-N 3.27Å; R21-R23 PolarHBondContact O-N 3.07Å; R21-R24 PolarHBondContact O-N 3.16Å; R21-E25 WeakPolarHBondContact CG-OE1 3.19Å; R21-E25 IonicContact NE-OE1 2.77Å; R21-E25 WeakPolarHBondContact O-CG 3.19Å; R21-E25 PolarHBondContact O-N 3.24Å
22R97.7Very high97.7Very high109 Ų109112.4 Ų112.441%0.41150%0.496SS..Hα-helixtrans-66.8-24.9-179.6-65.3-171.464.185.63114F20 G26 K27 T28 F30F20-R22 PolarHBondContact O-N 2.89Å; R22-G26 PolarHBondContact O-N 3.23Å; R22-K27 PolarHBondContact O-N 3.15Å; R22-T28 PolarHBondContact NE-OG1 3.38Å; R22-T28 PolarHBondContact NH2-OG1 3.3Å; R22-F30 HydrophobicContact CB-CE2 4.14Å; R22-F30 HydrophobicContact CB-CZ 4.15Å
23R97.9Very high97.7Very high133 Ų133112.2 Ų112.250%0.50249%0.494SS..Hα-helixtrans-75.1-41.2173.3-17959.4-179.4145.90.7110.7K19 F20 R21 E25 G26 F30K19-R23 HydrophobicContact CB-CB 4.38Å; K19-R23 HydrophobicContact CB-CG 4.17Å; F20-R23 HydrophobicContact CB-CB 4.44Å; F20-R23 WeakPolarHBondContact O-CA 3.39Å; F20-R23 WeakPolarHBondContact O-CB 3.34Å; F20-R23 PolarHBondContact O-N 2.97Å; R21-R23 VanDerWaalsContact C-N 3.27Å; R21-R23 PolarHBondContact O-N 3.07Å; R23-E25 VanDerWaalsContact C-N 3.3Å; R23-E25 PolarHBondContact O-N 2.95Å; R23-G26 PolarHBondContact O-N 2.8Å; R23-F30 HydrophobicContact CB-CD2 4.22Å; R23-F30 HydrophobicContact CB-CE2 4.1Å
24R98Very high97.7Very high147 Ų147113 Ų11356%0.55550%0.498SS*.Hα-helixtrans-64-35.2173.6-59-168.8-54-121.716.7112.3K19 F20 R21 G26K19-R24 HydrophobicContact CB-CG 4.13Å; K19-R24 VanDerWaalsContact O-CD 3.28Å; K19-R24 WeakPolarHBondContact O-CD 3.46Å; K19-R24 WeakPolarHBondContact O-CG 3.43Å; K19-R24 PolarHBondContact O-NH1 3.09Å; F20-R24 PolarHBondContact O-N 3.45Å; R21-R24 PolarHBondContact O-N 3.16Å; R24-G26 PolarHBondContact O-N 3.46Å
25E97.5Very high97.8Very high89 Ų89111.4 Ų111.442%0.41649%0.487SS..THydrogen-bonded Turntrans-75.1-7172-69.5175.9-150.600113.6R21 R23 K27R21-E25 WeakPolarHBondContact CG-OE1 3.19Å; R21-E25 IonicContact NE-OE1 2.77Å; R21-E25 WeakPolarHBondContact O-CG 3.19Å; R21-E25 PolarHBondContact O-N 3.24Å; R23-E25 VanDerWaalsContact C-N 3.3Å; R23-E25 PolarHBondContact O-N 2.95Å; E25-K27 VanDerWaalsContact C-N 3.33Å; E25-K27 HydrophobicContact CB-CD 4.14Å; E25-K27 HydrophobicContact CB-CG 4.15Å; E25-K27 PolarHBondContact O-N 3.48Å; E25-K27 WeakPolarHBondContact OE2-CD 3.4Å; E25-K27 WeakPolarHBondContact OE2-CE 3.47Å; E25-K27 IonicContact OE2-NZ 2.75Å; E25-K27 PolarHBondContact OE2-NZ 3.49Å
26G97.3Very high97.8Very high41 Ų41103.5 Ų103.542%0.42346%0.46SS..THydrogen-bonded Turntrans67.327.4179.400000114.6R22 R23 R24 L150R22-G26 PolarHBondContact O-N 3.23Å; R23-G26 PolarHBondContact O-N 2.8Å; R24-G26 PolarHBondContact O-N 3.46Å; G26-L150 WeakPolarHBondContact O-CD1 3.28Å
27K97.1Very high97.8Very high114 Ų11499 Ų9950%0.49645%0.445SS..  trans-106.3-9.9-173.9-66.6177.9-174161.70114.6R22 E25R22-K27 PolarHBondContact O-N 3.15Å; E25-K27 VanDerWaalsContact C-N 3.33Å; E25-K27 HydrophobicContact CB-CD 4.14Å; E25-K27 HydrophobicContact CB-CG 4.15Å; E25-K27 PolarHBondContact O-N 3.48Å; E25-K27 WeakPolarHBondContact OE2-CD 3.4Å; E25-K27 WeakPolarHBondContact OE2-CE 3.47Å; E25-K27 IonicContact OE2-NZ 2.75Å; E25-K27 PolarHBondContact OE2-NZ 3.49Å
28T97.6Very high97.7Very high16 Ų1695.2 Ų95.210%0.09843%0.432CS..  trans-149.5129.2-173.1-58.90000110.8R22 F30 R33R22-T28 PolarHBondContact NE-OG1 3.38Å; R22-T28 PolarHBondContact NH2-OG1 3.3Å; T28-F30 HydrophobicContact CG2-CD2 4.26Å; T28-F30 HydrophobicContact CG2-CE2 4.24Å; T28-F30 HydrophobicContact CG2-CG 4.48Å; T28-F30 HydrophobicContact CG2-CZ 4.42Å; T28-R33 HydrophobicContact CG2-CB 4.44Å
29D97.8Very high97.7Very high57 Ų5793.2 Ų93.231%0.30542%0.418SS..  trans-87.4114.5158.9177.619.2000109.4Y31 A32 R33 L150D29-Y31 VanDerWaalsContact C-N 3.28Å; D29-Y31 VanDerWaalsContact OD1-CB 3.3Å; D29-Y31 WeakPolarHBondContact OD1-CB 3.37Å; D29-Y31 PolarHBondContact OD1-N 2.86Å; D29-A32 HydrophobicContact CB-CB 4.34Å; D29-A32 WeakPolarHBondContact OD2-CB 3.28Å; D29-A32 PolarHBondContact OD2-N 3.4Å; D29-R33 VanDerWaalsContact O-CB 3.32Å; D29-R33 WeakPolarHBondContact O-CB 3.46Å; D29-R33 PolarHBondContact O-N 3.44Å; D29-R33 VanDerWaalsContact O-N 3.12Å; D29-L150 HydrophobicContact CB-CD2 3.71Å
30F97.9Very high97.7Very high72 Ų7290.9 Ų90.932%0.31641%0.411SS..Hα-helixtrans-74.9-20.5178.5-77.6-87.6000112.5F20 R22 R23 T28 K34F20-F30 HydrophobicContact CB-CD2 4.47Å; F20-F30 HydrophobicContact CB-CE2 3.75Å; F20-F30 HydrophobicContact CB-CZ 3.93Å; F20-F30 AromaticContact CD2-CD1 3.95Å; F20-F30 HydrophobicContact CD2-CD1 3.95Å; F20-F30 AromaticContact CD2-CD2 3.86Å; F20-F30 HydrophobicContact CD2-CD2 3.86Å; F20-F30 AromaticContact CD2-CE1 3.87Å; F20-F30 HydrophobicContact CD2-CE1 3.87Å; F20-F30 AromaticContact CD2-CE2 3.77Å; F20-F30 HydrophobicContact CD2-CE2 3.77Å; F20-F30 AromaticContact CD2-CG 3.94Å; F20-F30 HydrophobicContact CD2-CG 3.94Å; F20-F30 AromaticContact CD2-CZ 3.77Å; F20-F30 HydrophobicContact CD2-CZ 3.77Å; F20-F30 HydrophobicContact CE2-CD1 4.32Å; F20-F30 HydrophobicContact CE2-CE1 4.5Å; F20-F30 HydrophobicContact CE2-CG 4.44Å; F20-F30 HydrophobicContact CG-CE2 4.28Å; F20-F30 HydrophobicContact CG-CZ 4.31Å; R22-F30 HydrophobicContact CB-CE2 4.14Å; R22-F30 HydrophobicContact CB-CZ 4.15Å; R23-F30 HydrophobicContact CB-CD2 4.22Å; R23-F30 HydrophobicContact CB-CE2 4.1Å; T28-F30 HydrophobicContact CG2-CD2 4.26Å; T28-F30 HydrophobicContact CG2-CE2 4.24Å; T28-F30 HydrophobicContact CG2-CG 4.48Å; T28-F30 HydrophobicContact CG2-CZ 4.42Å; F30-K34 WeakPolarHBondContact O-CB 3.32Å; F30-K34 PolarHBondContact O-N 2.86Å
31Y98.2Very high97.6Very high155 Ų15592.5 Ų92.561%0.60842%0.418SS*.Hα-helixtrans-70.1-49.4177.1-175-96.3000111.4D29 R35D29-Y31 VanDerWaalsContact C-N 3.28Å; D29-Y31 VanDerWaalsContact OD1-CB 3.3Å; D29-Y31 WeakPolarHBondContact OD1-CB 3.37Å; D29-Y31 PolarHBondContact OD1-N 2.86Å; Y31-R35 VanDerWaalsContact CD2-NH1 3.27Å; Y31-R35 VanDerWaalsContact CE2-NH2 3.32Å; Y31-R35 PolarHBondContact O-NH1 3.27Å; Y31-R35 PolarHBondContact OH-NH2 3.14Å
32A97.6Very high97.6Very high44 Ų4490.1 Ų90.136%0.36442%0.418SS..Hα-helixtrans-62.6-46.917100000111.7D29 K34 R35 L36D29-A32 HydrophobicContact CB-CB 4.34Å; D29-A32 WeakPolarHBondContact OD2-CB 3.28Å; D29-A32 PolarHBondContact OD2-N 3.4Å; A32-K34 VanDerWaalsContact C-N 3.32Å; A32-K34 PolarHBondContact O-N 3.15Å; A32-R35 PolarHBondContact O-N 2.88Å; A32-R35 VanDerWaalsContact O-N 3.11Å; A32-L36 PolarHBondContact O-N 2.69Å
33R97.8Very high97.5Very high70 Ų7089.2 Ų89.226%0.26442%0.417SS..Hα-helixtrans-58.4-40.8-178.5-176.4175.8171.492.6-1.2112.9T28 D29 R35 L36 V37 D72T28-R33 HydrophobicContact CG2-CB 4.44Å; D29-R33 VanDerWaalsContact O-CB 3.32Å; D29-R33 WeakPolarHBondContact O-CB 3.46Å; D29-R33 PolarHBondContact O-N 3.44Å; D29-R33 VanDerWaalsContact O-N 3.12Å; R33-R35 VanDerWaalsContact C-N 3.26Å; R33-R35 PolarHBondContact O-N 3.49Å; R33-L36 PolarHBondContact O-N 3.49Å; R33-V37 HydrophobicContact CG-CG2 3.86Å; R33-V37 WeakPolarHBondContact O-CB 3.41Å; R33-V37 WeakPolarHBondContact O-CG2 3.49Å; R33-V37 PolarHBondContact O-N 2.91Å; R33-D72 IonicContact CZ-OD1 3.91Å; R33-D72 IonicContact CZ-OD2 2.86Å; R33-D72 IonicContact NH1-OD1 3.97Å; R33-D72 IonicContact NH1-OD2 3.43Å; R33-D72 PolarHBondContact NH1-OD2 3.08Å; R33-D72 IonicContact NH2-OD1 2.89Å; R33-D72 PolarHBondContact NH2-OD1 3.4Å; R33-D72 IonicContact NH2-OD2 3.8Å; R33-D72 PolarHBondContact NH2-OD2 3.35Å
34K97.6Very high97.4Very high149 Ų14992.4 Ų92.465%0.64843%0.431SS*.Hα-helixtrans-54.6-42.7177.5-179.1-178175.8-177.40111.6F30 A32 V38F30-K34 WeakPolarHBondContact O-CB 3.32Å; F30-K34 PolarHBondContact O-N 2.86Å; A32-K34 VanDerWaalsContact C-N 3.32Å; A32-K34 PolarHBondContact O-N 3.15Å; K34-V38 HydrophobicContact CG-CG2 4.48Å; K34-V38 VanDerWaalsContact O-CB 3.3Å; K34-V38 WeakPolarHBondContact O-CB 3.26Å; K34-V38 WeakPolarHBondContact O-CG2 3.2Å; K34-V38 PolarHBondContact O-N 2.92Å
35R97.9Very high97.3Very high135 Ų13593.1 Ų93.151%0.50945%0.446SS..Hα-helixtrans-77.8-35.2-178-69171.9175.574.91.8112.8Y31 A32 R33 K48Y31-R35 VanDerWaalsContact CD2-NH1 3.27Å; Y31-R35 VanDerWaalsContact CE2-NH2 3.32Å; Y31-R35 PolarHBondContact O-NH1 3.27Å; Y31-R35 PolarHBondContact OH-NH2 3.14Å; A32-R35 PolarHBondContact O-N 2.88Å; A32-R35 VanDerWaalsContact O-N 3.11Å; R33-R35 VanDerWaalsContact C-N 3.26Å; R33-R35 PolarHBondContact O-N 3.49Å; R35-K48 PolarHBondContact O-NZ 3.18Å
36L97.4Very high97.3Very high38 Ų3892.7 Ų92.720%0.19945%0.449CS..Hα-helixtrans-74.5-35-175.9-167.361.3000112.8A32 R33 K48 D147A32-L36 PolarHBondContact O-N 2.69Å; R33-L36 PolarHBondContact O-N 3.49Å; L36-K48 WeakPolarHBondContact O-CD 3.17Å; L36-K48 VanDerWaalsContact O-CE 3.26Å; L36-K48 WeakPolarHBondContact O-CE 3.32Å; L36-D147 HydrophobicContact CD2-CB 3.41Å; L36-D147 VanDerWaalsContact CD2-CB 3.41Å
37V97.1Very high97.3Very high26 Ų2692.8 Ų92.816%0.15844%0.442CS..Hα-helixtrans-100.1-32.6-168.7172.70000113.7R33 Q39 S67R33-V37 HydrophobicContact CG-CG2 3.86Å; R33-V37 WeakPolarHBondContact O-CB 3.41Å; R33-V37 WeakPolarHBondContact O-CG2 3.49Å; R33-V37 PolarHBondContact O-N 2.91Å; V37-Q39 PolarHBondContact O-N 3.15Å; V37-S67 WeakPolarHBondContact CG1-OG 3.31Å
38V96.9Very high97.3Very high79 Ų7989.4 Ų89.448%0.47943%0.428SS..PPolyproline II helixtrans-66129.8-177.9174.10000109.3K34 K48K34-V38 HydrophobicContact CG-CG2 4.48Å; K34-V38 VanDerWaalsContact O-CB 3.3Å; K34-V38 WeakPolarHBondContact O-CB 3.26Å; K34-V38 WeakPolarHBondContact O-CG2 3.2Å; K34-V38 PolarHBondContact O-N 2.92Å; V38-K48 WeakPolarHBondContact O-CD 3.45Å; V38-K48 PolarHBondContact O-NZ 3Å; V38-K48 VanDerWaalsContact O-NZ 3.1Å
39Q97.4Very high97.4Very high38 Ų3891.1 Ų91.118%0.17843%0.433CS..PPolyproline II helixtrans-94.2150.5176-175.864.6-72.300110.5V37 K43 T46 K48V37-Q39 PolarHBondContact O-N 3.15Å; Q39-K43 HydrophobicContact CG-CB 4.07Å; Q39-K43 HydrophobicContact CG-CD 4.49Å; Q39-T46 WeakPolarHBondContact CG-O 3.39Å; Q39-T46 PolarHBondContact NE2-O 3.25Å; Q39-K48 HydrophobicContact CB-CB 4.46Å
40D97.6Very high97.4Very high82 Ų8288.5 Ų88.544%0.43942%0.419SS..PPolyproline II helixtrans-61.1134.8172.4-52.8-38.1000110.3N42 K43D40-N42 VanDerWaalsContact C-N 3.26Å; D40-N42 VanDerWaalsContact CB-OD1 3.23Å; D40-N42 WeakPolarHBondContact CB-OD1 3.09Å; D40-N42 PolarHBondContact O-N 3.15Å; D40-K43 HydrophobicContact CB-CD 4.15Å; D40-K43 HydrophobicContact CB-CG 4.34Å; D40-K43 PolarHBondContact O-N 3.11Å; D40-K43 WeakPolarHBondContact OD2-CE 3.47Å; D40-K43 IonicContact OD2-NZ 2.95Å; D40-K43 PolarHBondContact OD2-NZ 3.23Å
41K96.6Very high97.4Very high177 Ų17785.1 Ų85.177%0.7740%0.404SS*.G310 helixtrans-68.1-26.3-170.7-63.3-57.4-172.5178.50113.7K43 Y44K41-K43 PolarHBondContact O-N 3.24Å; K41-Y44 PolarHBondContact O-N 2.88Å
42N97.6Very high97.5Very high121 Ų12178.5 Ų78.565%0.64738%0.379SS*.G310 helixtrans-72.3-10.2174.962.9-11.2000113.8D40 Y44D40-N42 VanDerWaalsContact C-N 3.26Å; D40-N42 VanDerWaalsContact CB-OD1 3.23Å; D40-N42 WeakPolarHBondContact CB-OD1 3.09Å; D40-N42 PolarHBondContact O-N 3.15Å; N42-Y44 VanDerWaalsContact O-CD2 3.29Å; N42-Y44 WeakPolarHBondContact O-CD2 3.2Å; N42-Y44 WeakPolarHBondContact O-CE2 3.47Å
43K96.2Very high97.5Very high91 Ų9176.4 Ų76.440%0.39636%0.362SS..G310 helixtrans-93.5-1.6175.3-63.7175.7179.4156.50113Q39 D40 K41 N45 T46Q39-K43 HydrophobicContact CG-CB 4.07Å; Q39-K43 HydrophobicContact CG-CD 4.49Å; D40-K43 HydrophobicContact CB-CD 4.15Å; D40-K43 HydrophobicContact CB-CG 4.34Å; D40-K43 PolarHBondContact O-N 3.11Å; D40-K43 WeakPolarHBondContact OD2-CE 3.47Å; D40-K43 IonicContact OD2-NZ 2.95Å; D40-K43 PolarHBondContact OD2-NZ 3.23Å; K41-K43 PolarHBondContact O-N 3.24Å; K43-N45 PolarHBondContact O-N 3.27Å; K43-T46 WeakPolarHBondContact O-CB 3.39Å; K43-T46 PolarHBondContact O-N 3.46Å; K43-T46 PolarHBondContact O-OG1 2.87Å; K43-T46 VanDerWaalsContact O-OG1 3.11Å
44Y95.3Very high97.5Very high199 Ų19977 Ų7778%0.7836%0.364SS*.THydrogen-bonded Turntrans47.6-106175.8-57.6-84000113.5K41 N42K41-Y44 PolarHBondContact O-N 2.88Å; N42-Y44 VanDerWaalsContact O-CD2 3.29Å; N42-Y44 WeakPolarHBondContact O-CD2 3.2Å; N42-Y44 WeakPolarHBondContact O-CE2 3.47Å
45N95.9Very high97.6Very high162 Ų16272.8 Ų72.887%0.86635%0.348SS*.THydrogen-bonded Turntrans-89.9-1-174.1-74.1-29.6000114.2K43 P47K43-N45 PolarHBondContact O-N 3.27Å; N45-P47 VanDerWaalsContact O-CD 3.31Å; N45-P47 WeakPolarHBondContact O-CD 3.4Å
46T97.4Very high97.5Very high81 Ų8169.5 Ų69.550%0.49735%0.346SS..  trans-63.8118.4-179.5-58.20000110.6Q39 K43Q39-T46 WeakPolarHBondContact CG-O 3.39Å; Q39-T46 PolarHBondContact NE2-O 3.25Å; K43-T46 WeakPolarHBondContact O-CB 3.39Å; K43-T46 PolarHBondContact O-N 3.46Å; K43-T46 PolarHBondContact O-OG1 2.87Å; K43-T46 VanDerWaalsContact O-OG1 3.11Å
47P97.6Very high97.5Very high42 Ų4275.3 Ų75.327%0.27338%0.377SS..  trans-69139.6-17827.1-33.6000111.5N45 Y49 Y66N45-P47 VanDerWaalsContact O-CD 3.31Å; N45-P47 WeakPolarHBondContact O-CD 3.4Å; P47-Y49 HydrophobicContact CB-CE1 4.14Å; P47-Y49 HydrophobicContact CB-CE2 4.22Å; P47-Y49 HydrophobicContact CG-CE1 4.1Å; P47-Y49 HydrophobicContact CG-CE2 3.63Å; P47-Y49 VanDerWaalsContact CG-OH 3.22Å; P47-Y49 WeakPolarHBondContact CG-OH 3.34Å; P47-Y66 HydrophobicContact CB-CD1 4.26Å; P47-Y66 HydrophobicContact CB-CD2 3.68Å; P47-Y66 HydrophobicContact CB-CE2 4.3Å; P47-Y66 HydrophobicContact CB-CG 3.65Å
48K98.2Very high97.5Very high44 Ų4483.9 Ų83.919%0.19141%0.407CS..  trans-95.5103.3169.3-168.5168.4177.7174.50109.2R35 L36 V38 Q39 Y145R35-K48 PolarHBondContact O-NZ 3.18Å; L36-K48 WeakPolarHBondContact O-CD 3.17Å; L36-K48 VanDerWaalsContact O-CE 3.26Å; L36-K48 WeakPolarHBondContact O-CE 3.32Å; V38-K48 WeakPolarHBondContact O-CD 3.45Å; V38-K48 PolarHBondContact O-NZ 3Å; V38-K48 VanDerWaalsContact O-NZ 3.1Å; Q39-K48 HydrophobicContact CB-CB 4.46Å; K48-Y145 HydrophobicContact CD-CE2 4.45Å; K48-Y145 HydrophobicContact CG-CD2 4.03Å; K48-Y145 HydrophobicContact CG-CE2 3.87Å
49Y98.6Very high97.6Very high52 Ų5281.9 Ų81.920%0.20439%0.393CS..  trans-79.9142.1-176.6-62.4-73.6000112.3P47 I64 A65 Y66 V75 F142 C144 Y145P47-Y49 HydrophobicContact CB-CE1 4.14Å; P47-Y49 HydrophobicContact CB-CE2 4.22Å; P47-Y49 HydrophobicContact CG-CE1 4.1Å; P47-Y49 HydrophobicContact CG-CE2 3.63Å; P47-Y49 VanDerWaalsContact CG-OH 3.22Å; P47-Y49 WeakPolarHBondContact CG-OH 3.34Å; Y49-I64 HydrophobicContact CD1-CG2 4.12Å; Y49-A65 CarbonylContact C-O 3.42Å; Y49-A65 WeakPolarHBondContact CA-O 3.39Å; Y49-Y66 AromaticContact CD1-CD1 3.96Å; Y49-Y66 HydrophobicContact CD1-CD1 3.96Å; Y49-Y66 HydrophobicContact CD1-CG 4.37Å; Y49-Y66 AromaticContact CE1-CD1 3.54Å; Y49-Y66 HydrophobicContact CE1-CD1 3.54Å; Y49-Y66 HydrophobicContact CE1-CE1 4.22Å; Y49-Y66 HydrophobicContact CE1-CG 4.17Å; Y49-V75 HydrophobicContact CD1-CG2 4.28Å; Y49-V75 HydrophobicContact CE1-CG2 3.89Å; Y49-F142 HydrophobicContact CD1-CE2 4.49Å; Y49-F142 AromaticContact CD1-CZ 3.69Å; Y49-F142 HydrophobicContact CD1-CZ 3.69Å; Y49-F142 HydrophobicContact CD2-CE1 4.14Å; Y49-F142 AromaticContact CD2-CE2 3.89Å; Y49-F142 HydrophobicContact CD2-CE2 3.89Å; Y49-F142 AromaticContact CD2-CZ 3.45Å; Y49-F142 HydrophobicContact CD2-CZ 3.45Å; Y49-F142 VanDerWaalsContact CD2-CZ 3.45Å; Y49-F142 HydrophobicContact CE1-CE2 4.39Å; Y49-F142 AromaticContact CE1-CZ 3.99Å; Y49-F142 HydrophobicContact CE1-CZ 3.99Å; Y49-F142 AromaticContact CE2-CE2 3.77Å; Y49-F142 HydrophobicContact CE2-CE2 3.77Å; Y49-F142 AromaticContact CE2-CZ 3.77Å; Y49-F142 HydrophobicContact CE2-CZ 3.77Å; Y49-F142 AromaticContact CG-CE1 3.98Å; Y49-F142 HydrophobicContact CG-CE1 3.98Å; Y49-F142 HydrophobicContact CG-CE2 4.25Å; Y49-F142 AromaticContact CG-CZ 3.4Å; Y49-F142 HydrophobicContact CG-CZ 3.4Å; Y49-C144 WeakPolarHBondContact O-CA 3.45Å; Y49-Y145 WeakPolarHBondContact O-CD2 3.46Å; Y49-Y145 PolarHBondContact O-N 3.47Å
50R98.5Very high97.7Very high2 Ų280 Ų801%0.00839%0.385CS..EExtended strand (participates in β ladder)trans-131.1140.9174.355.9177.1179.1-75.4-8111.8I52 I64 A65 S67 D72 Y145 D147R50-I52 HydrophobicContact CG-CD1 4.48Å; R50-I52 HydrophobicContact CG-CG1 4.02Å; R50-I64 WeakPolarHBondContact O-CA 3.4Å; R50-A65 HydrophobicContact CG-CB 4.4Å; R50-A65 VanDerWaalsContact CG-O 3.29Å; R50-A65 WeakPolarHBondContact CG-O 3.42Å; R50-A65 PolarHBondContact N-O 3.03Å; R50-A65 PolarHBondContact O-N 3.45Å; R50-S67 PolarHBondContact NH1-OG 3.06Å; R50-S67 PolarHBondContact NH2-OG 3.39Å; R50-D72 IonicContact CZ-OD1 3.37Å; R50-D72 IonicContact CZ-OD2 3.57Å; R50-D72 IonicContact NH2-OD1 2.73Å; R50-D72 PolarHBondContact NH2-OD1 3.01Å; R50-D72 IonicContact NH2-OD2 2.95Å; R50-D72 PolarHBondContact NH2-OD2 2.8Å; R50-Y145 CarbonylContact C-O 3.57Å; R50-Y145 WeakPolarHBondContact CA-O 3.4Å; R50-Y145 WeakPolarHBondContact CB-O 3.34Å; R50-D147 HydrophobicContact CB-CB 4.41Å
51L98.7Very high97.7Very high0 Ų077.3 Ų77.30%037%0.372CS..EExtended strand (participates in β ladder)trans-86.999.3167.817560000109V53 Q63 I64 L105 Y145 L146 D147 A166 I173L51-V53 HydrophobicContact CD1-CG2 4.29Å; L51-V53 HydrophobicContact CD2-CG2 4.27Å; L51-V53 HydrophobicContact CG-CG2 3.88Å; L51-V53 PolarHBondContact O-N 2.99Å; L51-Q63 CarbonylContact C-O 3.56Å; L51-Q63 WeakPolarHBondContact CA-O 3.42Å; L51-I64 HydrophobicContact CB-CD1 3.99Å; L51-I64 HydrophobicContact CD1-CD1 3.95Å; L51-L105 HydrophobicContact CD1-CD2 3.27Å; L51-Y145 PolarHBondContact N-O 3.48Å; L51-L146 HydrophobicContact CD2-CD1 4.32Å; L51-L146 HydrophobicContact CG-CD1 4.39Å; L51-D147 PolarHBondContact O-N 2.95Å; L51-A166 HydrophobicContact CD2-CB 3.79Å; L51-I173 HydrophobicContact CD2-CD1 3.59Å
52I98.8Very high97.8Very high16 Ų1668.9 Ų68.98%0.08234%0.335CS..EExtended strand (participates in β ladder)trans-82.8113.7175.6-54.2174.6000108.4R50 R54 C62 Q63 A65 D147R50-I52 HydrophobicContact CG-CD1 4.48Å; R50-I52 HydrophobicContact CG-CG1 4.02Å; I52-R54 HydrophobicContact CG2-CG 4.03Å; I52-C62 CarbonylContact O-C 3.57Å; I52-C62 WeakPolarHBondContact O-CA 3.48Å; I52-Q63 HydrophobicContact CB-CB 4.36Å; I52-Q63 PolarHBondContact N-O 3.4Å; I52-Q63 PolarHBondContact O-N 3.25Å; I52-A65 HydrophobicContact CD1-CB 3.66Å; I52-A65 HydrophobicContact CG1-CB 4.42Å; I52-D147 HydrophobicContact CG1-CB 4.16Å
53V98.7Very high97.9Very high1 Ų165 Ų651%0.00631%0.313CS..EExtended strand (participates in β ladder)trans-110.9123174.3-175.60000109.3L51 L146 D147 V159 A162L51-V53 HydrophobicContact CD1-CG2 4.29Å; L51-V53 HydrophobicContact CD2-CG2 4.27Å; L51-V53 HydrophobicContact CG-CG2 3.88Å; L51-V53 PolarHBondContact O-N 2.99Å; V53-L146 HydrophobicContact CG2-CD1 3.81Å; V53-D147 PolarHBondContact N-O 3.3Å; V53-V159 HydrophobicContact CB-CG1 4.12Å; V53-V159 HydrophobicContact CG1-CB 4.42Å; V53-V159 HydrophobicContact CG1-CG1 4.28Å; V53-V159 HydrophobicContact CG1-CG2 4.24Å; V53-A162 HydrophobicContact CG1-CB 3.84Å; V53-A162 HydrophobicContact CG2-CB 4.03Å
54R98.5Very high98Very high81 Ų8160.7 Ų60.731%0.30629%0.294SS..EExtended strand (participates in β ladder)trans-130.1121.4177.7-61.9-65.2177.7-96.31.2109.7I52 C61 D147 A148I52-R54 HydrophobicContact CG2-CG 4.03Å; R54-C61 HydrophobicContact CB-CB 4.46Å; R54-C61 PolarHBondContact N-O 2.77Å; R54-C61 PolarHBondContact O-N 2.66Å; R54-D147 IonicContact CZ-OD1 3.12Å; R54-D147 PolarHBondContact NH1-O 3.06Å; R54-D147 IonicContact NH1-OD1 4Å; R54-D147 PolarHBondContact NH1-OD1 3.03Å; R54-D147 VanDerWaalsContact NH2-CG 3.31Å; R54-D147 IonicContact NH2-OD1 3.44Å; R54-D147 PolarHBondContact NH2-OD1 3.47Å; R54-D147 IonicContact NH2-OD2 2.77Å; R54-D147 PolarHBondContact NH2-OD2 2.82Å; R54-A148 VanDerWaalsContact NH1-C 3.34Å
55L97.8Very high98.1Very high61 Ų6151.2 Ų51.232%0.31926%0.257SS..EExtended strand (participates in β ladder)trans-95.3124175.3-54.4173.4000108.4I60 K158 V159L55-I60 HydrophobicContact CD2-CB 4.32Å; L55-I60 HydrophobicContact CD2-CD1 4.01Å; L55-I60 HydrophobicContact CD2-CG1 3.76Å; L55-I60 HydrophobicContact CD2-CG2 3.91Å; L55-K158 HydrophobicContact CD1-CB 3.78Å; L55-K158 HydrophobicContact CD2-CB 4.31Å; L55-V159 HydrophobicContact CD1-CG2 3.89Å; L55-V159 HydrophobicContact CG-CG2 4.25Å
56S97.4Very high98.2Very high67 Ų6745.9 Ų45.947%0.46923%0.225SC..  trans-108176.2167.777.50000109.7R58 D59S56-R58 PolarHBondContact O-N 3.29Å; S56-D59 WeakPolarHBondContact CB-O 3.11Å; S56-D59 PolarHBondContact N-O 3.39Å; S56-D59 WeakPolarHBondContact OG-CA 3.33Å; S56-D59 WeakPolarHBondContact OG-CB 3.45Å; S56-D59 PolarHBondContact OG-N 3.25Å; S56-D59 PolarHBondContact OG-O 2.96Å
57N97.3Very high98.3Very high160 Ų16043.8 Ų43.886%0.85621%0.214SC*.SBendtrans-63-25.7-177.4-66.6-2.1000113.8
58R97.1Very high98.2Very high206 Ų20646.7 Ų46.778%0.77722%0.222SC*.SBendtrans-136.64.6-173.2-65.9-174.5179.71700.5114.3S56S56-R58 PolarHBondContact O-N 3.29Å
59D98.4Very high98.2Very high36 Ų3653.5 Ų53.519%0.19326%0.259CS..  trans-152.6149-177.2-161.721.2000110.5S56 S80 H81 T93S56-D59 WeakPolarHBondContact CB-O 3.11Å; S56-D59 PolarHBondContact N-O 3.39Å; S56-D59 WeakPolarHBondContact OG-CA 3.33Å; S56-D59 WeakPolarHBondContact OG-CB 3.45Å; S56-D59 PolarHBondContact OG-N 3.25Å; S56-D59 PolarHBondContact OG-O 2.96Å; D59-S80 WeakPolarHBondContact CA-OG 3.09Å; D59-S80 PolarHBondContact OD1-N 3.11Å; D59-S80 PolarHBondContact OD1-OG 2.94Å; D59-H81 IonicContact OD1-CG 3.29Å; D59-H81 PolarHBondContact OD1-N 3.43Å; D59-H81 VanDerWaalsContact OD1-N 3.08Å; D59-H81 IonicContact OD1-ND1 3.58Å; D59-H81 PolarHBondContact OD1-ND1 3.29Å; D59-H81 IonicContact OD2-CE1 3.54Å; D59-H81 IonicContact OD2-CG 2.85Å; D59-H81 IonicContact OD2-ND1 2.69Å; D59-H81 PolarHBondContact OD2-ND1 3.27Å; D59-T93 VanDerWaalsContact N-CG2 3.33Å
60I98.7Very high98.1Very high0 Ų058.4 Ų58.40%028%0.284CS..EExtended strand (participates in β ladder)trans-113127.5173-59.7-179.6000107.2L55 Y79 S80 A97 A98 T101L55-I60 HydrophobicContact CD2-CB 4.32Å; L55-I60 HydrophobicContact CD2-CD1 4.01Å; L55-I60 HydrophobicContact CD2-CG1 3.76Å; L55-I60 HydrophobicContact CD2-CG2 3.91Å; I60-Y79 CarbonylContact O-C 3.59Å; I60-Y79 VanDerWaalsContact O-CA 3.27Å; I60-Y79 WeakPolarHBondContact O-CA 3.37Å; I60-S80 PolarHBondContact N-OG 3.33Å; I60-S80 PolarHBondContact O-N 3.44Å; I60-A97 HydrophobicContact CD1-CB 4.45Å; I60-A98 HydrophobicContact CD1-CB 3.65Å; I60-T101 HydrophobicContact CB-CG2 4.26Å; I60-T101 HydrophobicContact CG2-CG2 4.28Å; I60-T101 WeakPolarHBondContact CG2-OG1 2.97Å
61C98.5Very high98Very high25 Ų2559.9 Ų59.917%0.16930%0.299CS..EExtended strand (participates in β ladder)trans-115.8121.4178.7174.80000109.4R54 Y79R54-C61 HydrophobicContact CB-CB 4.46Å; R54-C61 PolarHBondContact N-O 2.77Å; R54-C61 PolarHBondContact O-N 2.66Å; C61-Y79 HydrophobicContact CB-CD1 4Å; C61-Y79 HydrophobicContact CB-CE1 3.98Å; C61-Y79 WeakPolarHBondContact SG-CE1 3.3Å
62C98.8Very high98Very high0 Ų062.6 Ų62.60%031%0.314CS..EExtended strand (participates in β ladder)trans-120.8127.5176.7-65.80000108.6I52 A77 A78 L105I52-C62 CarbonylContact O-C 3.57Å; I52-C62 WeakPolarHBondContact O-CA 3.48Å; C62-A77 CarbonylContact O-C 3.02Å; C62-A77 WeakPolarHBondContact O-CA 3.5Å; C62-A78 PolarHBondContact N-O 3.07Å; C62-A78 PolarHBondContact O-N 3.15Å; C62-L105 HydrophobicContact CB-CB 4.44Å; C62-L105 HydrophobicContact CB-CD2 3.66Å
63Q98.7Very high98Very high39 Ų3964.3 Ų64.318%0.18232%0.321CS..EExtended strand (participates in β ladder)trans-138.5141.4-177.9-58.6-177.9-35.500111.3L51 I52 I74 S76 A77 Y79L51-Q63 CarbonylContact C-O 3.56Å; L51-Q63 WeakPolarHBondContact CA-O 3.42Å; I52-Q63 HydrophobicContact CB-CB 4.36Å; I52-Q63 PolarHBondContact N-O 3.4Å; I52-Q63 PolarHBondContact O-N 3.25Å; Q63-I74 HydrophobicContact CB-CD1 4.44Å; Q63-I74 HydrophobicContact CB-CG2 4.33Å; Q63-S76 WeakPolarHBondContact CA-O 3.48Å; Q63-A77 HydrophobicContact CG-CB 3.94Å; Q63-Y79 PolarHBondContact NE2-OH 2.94Å
64I98.7Very high97.9Very high0 Ų068 Ų680%034%0.34CS..EExtended strand (participates in β ladder)trans-96.6123.1165.2-62.7-66000108.3Y49 R50 L51 V75 S76 L105 L109 F142 C144 L171Y49-I64 HydrophobicContact CD1-CG2 4.12Å; R50-I64 WeakPolarHBondContact O-CA 3.4Å; L51-I64 HydrophobicContact CB-CD1 3.99Å; L51-I64 HydrophobicContact CD1-CD1 3.95Å; I64-V75 HydrophobicContact CB-CB 4.46Å; I64-V75 HydrophobicContact CG2-CB 4.17Å; I64-V75 HydrophobicContact CG2-CG2 4.3Å; I64-V75 PolarHBondContact O-N 2.79Å; I64-S76 PolarHBondContact N-O 2.77Å; I64-L105 HydrophobicContact CD1-CD2 4.32Å; I64-L105 HydrophobicContact CG1-CD1 4.26Å; I64-L105 HydrophobicContact CG1-CD2 4.01Å; I64-L105 HydrophobicContact CG1-CG 4.12Å; I64-L109 HydrophobicContact CB-CD1 4.34Å; I64-L109 HydrophobicContact CG1-CD1 4.41Å; I64-L109 HydrophobicContact CG1-CD2 4.06Å; I64-L109 HydrophobicContact CG2-CD1 4.31Å; I64-L109 HydrophobicContact CG2-CD2 4.47Å; I64-F142 HydrophobicContact CG2-CE1 3.98Å; I64-F142 HydrophobicContact CG2-CZ 3.95Å; I64-C144 HydrophobicContact CD1-CB 4.41Å; I64-L171 HydrophobicContact CD1-CD1 4.21Å
65A98.5Very high97.9Very high0 Ų065 Ų650%033%0.331CS..EExtended strand (participates in β ladder)trans-136.7154.9-178.600000112Y49 R50 I52 H73 I74Y49-A65 CarbonylContact C-O 3.42Å; Y49-A65 WeakPolarHBondContact CA-O 3.39Å; R50-A65 HydrophobicContact CG-CB 4.4Å; R50-A65 VanDerWaalsContact CG-O 3.29Å; R50-A65 WeakPolarHBondContact CG-O 3.42Å; R50-A65 PolarHBondContact N-O 3.03Å; R50-A65 PolarHBondContact O-N 3.45Å; I52-A65 HydrophobicContact CD1-CB 3.66Å; I52-A65 HydrophobicContact CG1-CB 4.42Å; A65-H73 VanDerWaalsContact CA-O 3.26Å; A65-H73 WeakPolarHBondContact CA-O 3.48Å; A65-I74 HydrophobicContact CB-CD1 3.64Å
66Y98.4Very high97.9Very high50 Ų5062.6 Ų62.620%0.19632%0.319CS..EExtended strand (participates in β ladder)trans-131.9165.316267.1-84.3000108.7P47 Y49 K68 D72 H73 V75P47-Y66 HydrophobicContact CB-CD1 4.26Å; P47-Y66 HydrophobicContact CB-CD2 3.68Å; P47-Y66 HydrophobicContact CB-CE2 4.3Å; P47-Y66 HydrophobicContact CB-CG 3.65Å; Y49-Y66 AromaticContact CD1-CD1 3.96Å; Y49-Y66 HydrophobicContact CD1-CD1 3.96Å; Y49-Y66 HydrophobicContact CD1-CG 4.37Å; Y49-Y66 AromaticContact CE1-CD1 3.54Å; Y49-Y66 HydrophobicContact CE1-CD1 3.54Å; Y49-Y66 HydrophobicContact CE1-CE1 4.22Å; Y49-Y66 HydrophobicContact CE1-CG 4.17Å; Y66-K68 HydrophobicContact CD2-CG 4.36Å; Y66-K68 HydrophobicContact CE2-CD 4.29Å; Y66-K68 HydrophobicContact CE2-CG 3.83Å; Y66-K68 VanDerWaalsContact OH-CE 3.27Å; Y66-K68 WeakPolarHBondContact OH-CE 3.32Å; Y66-D72 WeakPolarHBondContact O-CA 3.39Å; Y66-H73 HydrophobicContact CD1-CB 4.3Å; Y66-H73 HydrophobicContact CE1-CB 3.77Å; Y66-H73 HydrophobicContact CE2-CB 4.19Å; Y66-H73 PolarHBondContact N-O 3.13Å; Y66-H73 VanDerWaalsContact N-O 3.14Å; Y66-H73 PolarHBondContact O-N 3.27Å; Y66-V75 HydrophobicContact CD1-CG2 3.83Å; Y66-V75 HydrophobicContact CE1-CG2 3.89Å
67S97.8Very high97.9Very high38 Ų3860.5 Ų60.527%0.26631%0.306SS..EExtended strand (participates in β ladder)trans-104.7139.4-175.2-65.20000112.6V37 R50 D72V37-S67 WeakPolarHBondContact CG1-OG 3.31Å; R50-S67 PolarHBondContact NH1-OG 3.06Å; R50-S67 PolarHBondContact NH2-OG 3.39Å; S67-D72 WeakPolarHBondContact CB-OD1 3.12Å; S67-D72 PolarHBondContact OG-OD1 2.98Å
68K97.1Very high98Very high103 Ų10352.9 Ų52.945%0.44827%0.265SS..  trans-120.2176.6164.1-64.5-162.7-155.6168.20109.9Y66 E70 G71 H73Y66-K68 HydrophobicContact CD2-CG 4.36Å; Y66-K68 HydrophobicContact CE2-CD 4.29Å; Y66-K68 HydrophobicContact CE2-CG 3.83Å; Y66-K68 VanDerWaalsContact OH-CE 3.27Å; Y66-K68 WeakPolarHBondContact OH-CE 3.32Å; K68-E70 HydrophobicContact CB-CG 4.32Å; K68-G71 CarbonylContact C-O 3.57Å; K68-G71 WeakPolarHBondContact CA-O 3.2Å; K68-G71 PolarHBondContact N-O 3.08Å; K68-G71 PolarHBondContact O-N 3.2Å; K68-H73 VanDerWaalsContact CD-CD2 3.48Å; K68-H73 WeakPolarHBondContact CD-CD2 3.35Å; K68-H73 WeakPolarHBondContact CD-NE2 3.26Å; K68-H73 VanDerWaalsContact CE-CD2 3.48Å; K68-H73 WeakPolarHBondContact CE-CD2 3.47Å; K68-H73 WeakPolarHBondContact CE-NE2 3.43Å; K68-H73 WeakPolarHBondContact CG-CD2 3.23Å
69I96.6Very high98.1Very high186 Ų18646.1 Ų46.195%0.95424%0.24SC*.SBendtrans-64-41.5179.9-61.3174000111.1G71I69-G71 VanDerWaalsContact C-N 3.31Å; I69-G71 PolarHBondContact O-N 3.18Å
70E97.3Very high98.1Very high156 Ų15644.4 Ų44.473%0.72923%0.231SC*.SBendtrans-70.4-26.2179.162.1-176161.300113.5K68 H73K68-E70 HydrophobicContact CB-CG 4.32Å; E70-H73 IonicContact OE1-CE1 3.91Å; E70-H73 PolarHBondContact OE1-CE1 3.27Å; E70-H73 IonicContact OE1-NE2 4Å; E70-H73 PolarHBondContact OE1-NE2 3.4Å
71G96.5Very high98Very high32 Ų3249.3 Ų49.333%0.3325%0.253SS..  trans157.8-175.8-174.900000113K68 I69K68-G71 CarbonylContact C-O 3.57Å; K68-G71 WeakPolarHBondContact CA-O 3.2Å; K68-G71 PolarHBondContact N-O 3.08Å; K68-G71 PolarHBondContact O-N 3.2Å; I69-G71 VanDerWaalsContact C-N 3.31Å; I69-G71 PolarHBondContact O-N 3.18Å
72D98.1Very high97.9Very high58 Ų5848.7 Ų48.731%0.3125%0.248SC..EExtended strand (participates in β ladder)trans-83.1130.9176.3-66.4-20.5000110.1R33 R50 Y66 S67R33-D72 IonicContact CZ-OD1 3.91Å; R33-D72 IonicContact CZ-OD2 2.86Å; R33-D72 IonicContact NH1-OD1 3.97Å; R33-D72 IonicContact NH1-OD2 3.43Å; R33-D72 PolarHBondContact NH1-OD2 3.08Å; R33-D72 IonicContact NH2-OD1 2.89Å; R33-D72 PolarHBondContact NH2-OD1 3.4Å; R33-D72 IonicContact NH2-OD2 3.8Å; R33-D72 PolarHBondContact NH2-OD2 3.35Å; R50-D72 IonicContact CZ-OD1 3.37Å; R50-D72 IonicContact CZ-OD2 3.57Å; R50-D72 IonicContact NH2-OD1 2.73Å; R50-D72 PolarHBondContact NH2-OD1 3.01Å; R50-D72 IonicContact NH2-OD2 2.95Å; R50-D72 PolarHBondContact NH2-OD2 2.8Å; Y66-D72 WeakPolarHBondContact O-CA 3.39Å; S67-D72 WeakPolarHBondContact CB-OD1 3.12Å; S67-D72 PolarHBondContact OG-OD1 2.98Å
73H98.3Very high97.8Very high52 Ų5248.7 Ų48.724%0.24125%0.248CC..EExtended strand (participates in β ladder)trans-95121.3172.9-71.5-100.1000109.3A65 Y66 K68 E70A65-H73 VanDerWaalsContact CA-O 3.26Å; A65-H73 WeakPolarHBondContact CA-O 3.48Å; Y66-H73 HydrophobicContact CD1-CB 4.3Å; Y66-H73 HydrophobicContact CE1-CB 3.77Å; Y66-H73 HydrophobicContact CE2-CB 4.19Å; Y66-H73 PolarHBondContact N-O 3.13Å; Y66-H73 VanDerWaalsContact N-O 3.14Å; Y66-H73 PolarHBondContact O-N 3.27Å; K68-H73 VanDerWaalsContact CD-CD2 3.48Å; K68-H73 WeakPolarHBondContact CD-CD2 3.35Å; K68-H73 WeakPolarHBondContact CD-NE2 3.26Å; K68-H73 VanDerWaalsContact CE-CD2 3.48Å; K68-H73 WeakPolarHBondContact CE-CD2 3.47Å; K68-H73 WeakPolarHBondContact CE-NE2 3.43Å; K68-H73 WeakPolarHBondContact CG-CD2 3.23Å; E70-H73 IonicContact OE1-CE1 3.91Å; E70-H73 PolarHBondContact OE1-CE1 3.27Å; E70-H73 IonicContact OE1-NE2 4Å; E70-H73 PolarHBondContact OE1-NE2 3.4Å
74I98.4Very high97.7Very high78 Ų7849.1 Ų49.140%0.425%0.254SS..EExtended strand (participates in β ladder)trans-85.3122.5174.3-52.6-55.4000108.7Q63 A65 S76 A77Q63-I74 HydrophobicContact CB-CD1 4.44Å; Q63-I74 HydrophobicContact CB-CG2 4.33Å; A65-I74 HydrophobicContact CB-CD1 3.64Å; I74-S76 WeakPolarHBondContact CG2-O 3.35Å; I74-A77 HydrophobicContact CG2-CB 4.32Å
75V97.8Very high97.6Very high19 Ų1955.2 Ų55.212%0.11528%0.28CS..EExtended strand (participates in β ladder)trans-85.3-46.8179.2-176.90000110.6Y49 I64 Y66 L109 K112 F113Y49-V75 HydrophobicContact CD1-CG2 4.28Å; Y49-V75 HydrophobicContact CE1-CG2 3.89Å; I64-V75 HydrophobicContact CB-CB 4.46Å; I64-V75 HydrophobicContact CG2-CB 4.17Å; I64-V75 HydrophobicContact CG2-CG2 4.3Å; I64-V75 PolarHBondContact O-N 2.79Å; Y66-V75 HydrophobicContact CD1-CG2 3.83Å; Y66-V75 HydrophobicContact CE1-CG2 3.89Å; V75-L109 HydrophobicContact CB-CD1 4.25Å; V75-L109 HydrophobicContact CG1-CD1 3.58Å; V75-K112 PolarHBondContact O-NZ 3.14Å; V75-F113 HydrophobicContact CG1-CE2 4.07Å; V75-F113 HydrophobicContact CG1-CZ 3.62Å
76S97.8Very high97.5Very high10 Ų1056.3 Ų56.37%0.0729%0.285CS..EExtended strand (participates in β ladder)trans-149.7153.1178.9-1700000109.3Q63 I64 I74Q63-S76 WeakPolarHBondContact CA-O 3.48Å; I64-S76 PolarHBondContact N-O 2.77Å; I74-S76 WeakPolarHBondContact CG2-O 3.35Å
77A98.2Very high97.4Very high22 Ų2255.8 Ų55.818%0.18230%0.295CS..EExtended strand (participates in β ladder)trans-140.5148.4178.100000109.7C62 Q63 I74 Y79 R108C62-A77 CarbonylContact O-C 3.02Å; C62-A77 WeakPolarHBondContact O-CA 3.5Å; Q63-A77 HydrophobicContact CG-CB 3.94Å; I74-A77 HydrophobicContact CG2-CB 4.32Å; A77-Y79 HydrophobicContact CB-CE2 3.92Å; A77-R108 PolarHBondContact O-NH1 2.98Å
78A98.4Very high97.3Very high0 Ų054 Ų540%028%0.282CS..EExtended strand (participates in β ladder)trans-139.4148171.400000109.5C62 L104 L105C62-A78 PolarHBondContact N-O 3.07Å; C62-A78 PolarHBondContact O-N 3.15Å; A78-L104 HydrophobicContact CB-CB 4.36Å; A78-L104 HydrophobicContact CB-CD2 4.15Å; A78-L104 HydrophobicContact CB-CG 4.07Å; A78-L105 HydrophobicContact CB-CB 3.81Å; A78-L105 HydrophobicContact CB-CD1 4.36Å
79Y98.4Very high97.2Very high65 Ų6553.4 Ų53.426%0.25528%0.284SS..EExtended strand (participates in β ladder)trans-134.7148.7-176.4-59.2-91.9000111.1I60 C61 Q63 A77 H81 E82I60-Y79 CarbonylContact O-C 3.59Å; I60-Y79 VanDerWaalsContact O-CA 3.27Å; I60-Y79 WeakPolarHBondContact O-CA 3.37Å; C61-Y79 HydrophobicContact CB-CD1 4Å; C61-Y79 HydrophobicContact CB-CE1 3.98Å; C61-Y79 WeakPolarHBondContact SG-CE1 3.3Å; Q63-Y79 PolarHBondContact NE2-OH 2.94Å; A77-Y79 HydrophobicContact CB-CE2 3.92Å; Y79-H81 VanDerWaalsContact C-N 3.29Å; Y79-H81 WeakPolarHBondContact CB-CE1 3.39Å; Y79-H81 VanDerWaalsContact CB-ND1 3.31Å; Y79-H81 WeakPolarHBondContact CB-ND1 3.42Å; Y79-H81 AromaticContact CD1-CE1 3.67Å; Y79-H81 AromaticContact CD2-CE1 3.95Å; Y79-H81 AromaticContact CG-CE1 3.32Å; Y79-H81 AromaticContact CG-ND1 3.92Å; Y79-H81 PolarHBondContact O-N 3.16Å; Y79-E82 WeakPolarHBondContact CD2-OE1 3.46Å; Y79-E82 WeakPolarHBondContact O-CB 3.42Å; Y79-E82 PolarHBondContact O-N 3.27Å; Y79-E82 VanDerWaalsContact O-N 3.13Å
80S98.3Very high97.1Very high0 Ų044.9 Ų44.90%024%0.241CC..G310 helixtrans-72.2-24.3179.464.70000113.2D59 I60 E82 L83 L92 T101D59-S80 WeakPolarHBondContact CA-OG 3.09Å; D59-S80 PolarHBondContact OD1-N 3.11Å; D59-S80 PolarHBondContact OD1-OG 2.94Å; I60-S80 PolarHBondContact N-OG 3.33Å; I60-S80 PolarHBondContact O-N 3.44Å; S80-E82 PolarHBondContact O-N 3.18Å; S80-E82 VanDerWaalsContact O-N 3.15Å; S80-L83 VanDerWaalsContact O-CB 3.26Å; S80-L83 WeakPolarHBondContact O-CB 3.45Å; S80-L83 WeakPolarHBondContact O-CG 3.36Å; S80-L83 PolarHBondContact O-N 3.3Å; S80-L92 WeakPolarHBondContact CB-O 3.24Å; S80-L92 PolarHBondContact OG-O 3.18Å; S80-T101 VanDerWaalsContact CA-CG2 3.48Å
81H97.3Very high97Very high103 Ų10338.6 Ų38.648%0.47722%0.217SC..G310 helixtrans-66.3-8170.270.1-102.4000114.6D59 Y79D59-H81 IonicContact OD1-CG 3.29Å; D59-H81 PolarHBondContact OD1-N 3.43Å; D59-H81 VanDerWaalsContact OD1-N 3.08Å; D59-H81 IonicContact OD1-ND1 3.58Å; D59-H81 PolarHBondContact OD1-ND1 3.29Å; D59-H81 IonicContact OD2-CE1 3.54Å; D59-H81 IonicContact OD2-CG 2.85Å; D59-H81 IonicContact OD2-ND1 2.69Å; D59-H81 PolarHBondContact OD2-ND1 3.27Å; Y79-H81 VanDerWaalsContact C-N 3.29Å; Y79-H81 WeakPolarHBondContact CB-CE1 3.39Å; Y79-H81 VanDerWaalsContact CB-ND1 3.31Å; Y79-H81 WeakPolarHBondContact CB-ND1 3.42Å; Y79-H81 AromaticContact CD1-CE1 3.67Å; Y79-H81 AromaticContact CD2-CE1 3.95Å; Y79-H81 AromaticContact CG-CE1 3.32Å; Y79-H81 AromaticContact CG-ND1 3.92Å; Y79-H81 PolarHBondContact O-N 3.16Å
82E96.3Very high97.1Very high12 Ų1238.8 Ų38.86%0.05621%0.211CC..G310 helixtrans-87.7-19169.7-60.8-179.8-16300112.5Y79 S80 P84 K85 R108 H253Y79-E82 WeakPolarHBondContact CD2-OE1 3.46Å; Y79-E82 WeakPolarHBondContact O-CB 3.42Å; Y79-E82 PolarHBondContact O-N 3.27Å; Y79-E82 VanDerWaalsContact O-N 3.13Å; S80-E82 PolarHBondContact O-N 3.18Å; S80-E82 VanDerWaalsContact O-N 3.15Å; E82-P84 VanDerWaalsContact C-N 3.34Å; E82-K85 WeakPolarHBondContact O-CB 3.38Å; E82-K85 PolarHBondContact O-N 3.5Å; E82-K85 VanDerWaalsContact O-N 3.11Å; E82-R108 IonicContact OE1-NH1 3.71Å; E82-R108 IonicContact OE2-CZ 3.31Å; E82-R108 VanDerWaalsContact OE2-CZ 3.31Å; E82-R108 IonicContact OE2-NH1 2.88Å; E82-R108 PolarHBondContact OE2-NH1 2.98Å; E82-R108 IonicContact OE2-NH2 2.79Å; E82-R108 PolarHBondContact OE2-NH2 2.76Å; E82-H253 IonicContact OE1-CE1 3.27Å; E82-H253 PolarHBondContact OE1-CE1 3.05Å; E82-H253 VanDerWaalsContact OE1-CE1 3.27Å; E82-H253 IonicContact OE1-ND1 3.18Å; E82-H253 PolarHBondContact OE1-ND1 2.86Å; E82-H253 IonicContact OE2-ND1 3.3Å; E82-H253 PolarHBondContact OE2-ND1 3.2Å
83L97.1Very high97.1Very high0 Ų038 Ų380%021%0.208CC..G310 helixtrans-60.3-26.9-177.2-62.7177.1000116S80 K85 Y86 G87 I88 L92 A97 C100 T101 L104 I247S80-L83 VanDerWaalsContact O-CB 3.26Å; S80-L83 WeakPolarHBondContact O-CB 3.45Å; S80-L83 WeakPolarHBondContact O-CG 3.36Å; S80-L83 PolarHBondContact O-N 3.3Å; L83-K85 PolarHBondContact O-N 2.98Å; L83-K85 VanDerWaalsContact O-N 3.15Å; L83-Y86 HydrophobicContact CD2-CD2 4.49Å; L83-Y86 CarbonylContact O-C 3.57Å; L83-Y86 WeakPolarHBondContact O-CA 3.48Å; L83-Y86 PolarHBondContact O-N 3.08Å; L83-G87 PolarHBondContact O-N 2.79Å; L83-I88 CarbonylContact C-O 3.53Å; L83-I88 HydrophobicContact CB-CB 4.05Å; L83-I88 HydrophobicContact CB-CD1 4.25Å; L83-I88 HydrophobicContact CD1-CD1 4.2Å; L83-I88 HydrophobicContact CD2-CD1 4.46Å; L83-I88 PolarHBondContact O-N 2.74Å; L83-L92 HydrophobicContact CB-CD2 4.17Å; L83-A97 HydrophobicContact CD1-CB 3.99Å; L83-C100 HydrophobicContact CD1-CB 3.98Å; L83-C100 HydrophobicContact CD2-CB 3.82Å; L83-T101 HydrophobicContact CD1-CG2 3.89Å; L83-T101 HydrophobicContact CD2-CG2 4.49Å; L83-T101 HydrophobicContact CG-CG2 4.26Å; L83-L104 HydrophobicContact CD2-CD2 4.38Å; L83-I247 HydrophobicContact CD2-CD1 4.2Å
84P97Very high97.1Very high47 Ų4736.8 Ų36.831%0.30520%0.203SC..G310 helixtrans-55.7-28.9171.9-29.837.1000113.9E82 Y86 G87 I88 L92E82-P84 VanDerWaalsContact C-N 3.34Å; P84-Y86 PolarHBondContact O-N 3.24Å; P84-G87 PolarHBondContact O-N 2.88Å; P84-I88 WeakPolarHBondContact CA-O 3.48Å; P84-I88 WeakPolarHBondContact CG-O 3.36Å; P84-L92 HydrophobicContact CG-CD1 4.33Å; P84-L92 HydrophobicContact CG-CD2 4.34Å
85K95.8Very high97.1Very high128 Ų12833.7 Ų33.756%0.55719%0.187SC*.G310 helixtrans-64.1-22.8174.4-64-174.9174.2-1680113.2E82 L83E82-K85 WeakPolarHBondContact O-CB 3.38Å; E82-K85 PolarHBondContact O-N 3.5Å; E82-K85 VanDerWaalsContact O-N 3.11Å; L83-K85 PolarHBondContact O-N 2.98Å; L83-K85 VanDerWaalsContact O-N 3.15Å
86Y97.2Very high97.1Very high23 Ų2332.8 Ų32.89%0.0918%0.182CC..G310 helixtrans-10513.5-178.4-54.9-76000112.2L83 P84 L104 A243 A246 I247 N250L83-Y86 HydrophobicContact CD2-CD2 4.49Å; L83-Y86 CarbonylContact O-C 3.57Å; L83-Y86 WeakPolarHBondContact O-CA 3.48Å; L83-Y86 PolarHBondContact O-N 3.08Å; P84-Y86 PolarHBondContact O-N 3.24Å; Y86-L104 HydrophobicContact CD2-CD2 4.48Å; Y86-L104 HydrophobicContact CE2-CD1 3.94Å; Y86-L104 HydrophobicContact CE2-CD2 3.79Å; Y86-A243 VanDerWaalsContact O-CA 3.26Å; Y86-A243 WeakPolarHBondContact O-CA 3.42Å; Y86-A243 WeakPolarHBondContact O-CB 3.49Å; Y86-A246 HydrophobicContact CD1-CB 4.05Å; Y86-I247 HydrophobicContact CD1-CG1 3.82Å; Y86-I247 HydrophobicContact CD2-CG1 4.04Å; Y86-I247 HydrophobicContact CE1-CG1 4.28Å; Y86-I247 HydrophobicContact CE2-CG1 4.49Å; Y86-I247 HydrophobicContact CG-CG1 3.68Å; Y86-N250 WeakPolarHBondContact CE1-O 3.24Å; Y86-N250 PolarHBondContact OH-O 3.3Å
87G95.4Very high97.1Very high40 Ų4032.3 Ų32.341%0.41218%0.178SC..THydrogen-bonded Turntrans97.3-1.6175.300000115.8L83 P84 N89L83-G87 PolarHBondContact O-N 2.79Å; P84-G87 PolarHBondContact O-N 2.88Å; G87-N89 PolarHBondContact O-N 3.41Å
88I96.6Very high97.2Very high0 Ų031.3 Ų31.30%017%0.17CC..  trans-98.391177.6-54.2163.6000109.5L83 P84 V90 L92 C100 Y240 A243L83-I88 CarbonylContact C-O 3.53Å; L83-I88 HydrophobicContact CB-CB 4.05Å; L83-I88 HydrophobicContact CB-CD1 4.25Å; L83-I88 HydrophobicContact CD1-CD1 4.2Å; L83-I88 HydrophobicContact CD2-CD1 4.46Å; L83-I88 PolarHBondContact O-N 2.74Å; P84-I88 WeakPolarHBondContact CA-O 3.48Å; P84-I88 WeakPolarHBondContact CG-O 3.36Å; I88-V90 VanDerWaalsContact CG2-O 3.3Å; I88-V90 WeakPolarHBondContact CG2-O 3.3Å; I88-L92 HydrophobicContact CG2-CD2 4.04Å; I88-L92 WeakPolarHBondContact O-CD2 3.28Å; I88-C100 HydrophobicContact CD1-CB 4.06Å; I88-C100 VanDerWaalsContact CD1-SG 3.58Å; I88-Y240 HydrophobicContact CD1-CD1 3.7Å; I88-Y240 HydrophobicContact CD1-CE1 3.69Å; I88-Y240 HydrophobicContact CG1-CD1 4.16Å; I88-Y240 HydrophobicContact CG1-CE1 4.07Å; I88-Y240 HydrophobicContact CG2-CE1 4.12Å; I88-A243 HydrophobicContact CD1-CB 3.51Å; I88-A243 HydrophobicContact CG1-CB 3.6Å
89N94.6Very high97.2Very high90 Ų9031.3 Ų31.348%0.48117%0.17SC..  trans-82.6-22.8-176.4-68.7-38.3000114.2G87G87-N89 PolarHBondContact O-N 3.41Å
90V95.6Very high97.2Very high8 Ų828.2 Ų28.25%0.04816%0.158CC..SBendtrans-135.2168.9-175.3-66.30000111.2I88 L92 R225 F226 N229 V231I88-V90 VanDerWaalsContact CG2-O 3.3Å; I88-V90 WeakPolarHBondContact CG2-O 3.3Å; V90-L92 PolarHBondContact O-N 2.96Å; V90-R225 HydrophobicContact CG1-CB 4.02Å; V90-F226 HydrophobicContact CB-CD2 4.18Å; V90-F226 HydrophobicContact CB-CE2 4.03Å; V90-F226 HydrophobicContact CB-CZ 4.26Å; V90-F226 HydrophobicContact CG2-CD1 3.73Å; V90-F226 HydrophobicContact CG2-CD2 3.94Å; V90-F226 HydrophobicContact CG2-CE1 3.67Å; V90-F226 HydrophobicContact CG2-CE2 3.89Å; V90-F226 HydrophobicContact CG2-CG 3.86Å; V90-F226 HydrophobicContact CG2-CZ 3.75Å; V90-N229 HydrophobicContact CG1-CB 4.29Å; V90-N229 WeakPolarHBondContact CG1-ND2 3.18Å; V90-V231 HydrophobicContact CG2-CG2 4.04Å
91G95Very high97.2Very high23 Ų2328.2 Ų28.224%0.23716%0.158CC..  trans72.522.5176.300000115.2T93 N94G91-T93 PolarHBondContact O-N 3.25Å; G91-N94 PolarHBondContact O-N 3Å; G91-N94 VanDerWaalsContact O-N 3.15Å; G91-N94 PolarHBondContact O-OD1 2.95Å; G91-N94 VanDerWaalsContact O-OD1 3.05Å
92L97.7Very high97.3Very high36 Ų3623.3 Ų23.319%0.18814%0.135CC..THydrogen-bonded Turntrans-61.61.7-170.8-55.1-177.6000116.8S80 L83 P84 I88 V90S80-L92 WeakPolarHBondContact CB-O 3.24Å; S80-L92 PolarHBondContact OG-O 3.18Å; L83-L92 HydrophobicContact CB-CD2 4.17Å; P84-L92 HydrophobicContact CG-CD1 4.33Å; P84-L92 HydrophobicContact CG-CD2 4.34Å; I88-L92 HydrophobicContact CG2-CD2 4.04Å; I88-L92 WeakPolarHBondContact O-CD2 3.28Å; V90-L92 PolarHBondContact O-N 2.96Å
93T98Very high97.4Very high41 Ų4122.7 Ų22.725%0.25213%0.132SC..THydrogen-bonded Turntrans-130.19.7-178.456.60000113.8D59 G91 K158D59-T93 VanDerWaalsContact N-CG2 3.33Å; G91-T93 PolarHBondContact O-N 3.25Å; T93-K158 WeakPolarHBondContact O-CD 3.42Å; T93-K158 WeakPolarHBondContact O-CE 3.47Å; T93-K158 PolarHBondContact O-NZ 3.27Å
94N97.9Very high97.4Very high27 Ų2722.7 Ų22.714%0.14413%0.132CC..SBendtrans-79.7-175.8174.868.84.5000111.2G91 A96 A97 A98 Y240G91-N94 PolarHBondContact O-N 3Å; G91-N94 VanDerWaalsContact O-N 3.15Å; G91-N94 PolarHBondContact O-OD1 2.95Å; G91-N94 VanDerWaalsContact O-OD1 3.05Å; N94-A96 PolarHBondContact OD1-N 3.12Å; N94-A97 WeakPolarHBondContact OD1-CB 3.32Å; N94-A97 PolarHBondContact OD1-N 3.43Å; N94-A98 PolarHBondContact O-N 2.89Å; N94-Y240 PolarHBondContact ND2-OH 3.12Å
95Y98.5Very high97.5Very high13 Ų1320.5 Ų20.55%0.05112%0.118CC..Hα-helixtrans-67.4-44.3-179.9-167.4-85.3000112.2A97 A98 Y99 K158 G161 P181 H195 H198 I199Y95-A97 PolarHBondContact O-N 3.02Å; Y95-A98 WeakPolarHBondContact O-CA 3.37Å; Y95-A98 VanDerWaalsContact O-CB 3.27Å; Y95-A98 WeakPolarHBondContact O-CB 3.44Å; Y95-A98 PolarHBondContact O-N 2.86Å; Y95-Y99 PolarHBondContact O-N 3.13Å; Y95-K158 HydrophobicContact CD2-CG 4.1Å; Y95-G161 WeakPolarHBondContact OH-CA 3.44Å; Y95-G161 PolarHBondContact OH-N 3.05Å; Y95-P181 HydrophobicContact CD2-CG 4.21Å; Y95-P181 HydrophobicContact CE1-CG 4.31Å; Y95-P181 HydrophobicContact CE2-CG 3.63Å; Y95-P181 VanDerWaalsContact OH-CD 3.29Å; Y95-P181 WeakPolarHBondContact OH-CD 3.35Å; Y95-H195 AromaticContact CZ-NE2 3.94Å; Y95-H195 PolarHBondContact OH-NE2 3.28Å; Y95-H198 HydrophobicContact CD1-CB 3.91Å; Y95-H198 HydrophobicContact CE1-CB 4.23Å; Y95-H198 HydrophobicContact CG-CB 4.37Å; Y95-I199 HydrophobicContact CE1-CG1 3.99Å
96A98.4Very high97.7Very high1 Ų114.4 Ų14.41%0.0089%0.091CC..Hα-helixtrans-59.1-43.4177.200000112.9N94 A98 Y99 C100 I199 Y240N94-A96 PolarHBondContact OD1-N 3.12Å; A96-A98 VanDerWaalsContact C-N 3.33Å; A96-A98 PolarHBondContact O-N 3.42Å; A96-Y99 WeakPolarHBondContact O-CB 3.23Å; A96-Y99 PolarHBondContact O-N 2.88Å; A96-C100 PolarHBondContact O-N 3.49Å; A96-C100 PolarHBondContact O-SG 2.68Å; A96-I199 WeakPolarHBondContact CA-O 3.47Å; A96-I199 WeakPolarHBondContact CB-O 3.21Å; A96-Y240 HydrophobicContact CB-CD1 3.87Å; A96-Y240 HydrophobicContact CB-CD2 4.01Å; A96-Y240 HydrophobicContact CB-CE1 3.49Å; A96-Y240 VanDerWaalsContact CB-CE1 3.49Å; A96-Y240 HydrophobicContact CB-CE2 3.66Å; A96-Y240 HydrophobicContact CB-CG 4.13Å
97A98.4Very high97.7Very high0 Ų014.2 Ų14.20%09%0.09CC..Hα-helixtrans-64.2-37.4173.200000111.8I60 L83 N94 Y95 C100 T101I60-A97 HydrophobicContact CD1-CB 4.45Å; L83-A97 HydrophobicContact CD1-CB 3.99Å; N94-A97 WeakPolarHBondContact OD1-CB 3.32Å; N94-A97 PolarHBondContact OD1-N 3.43Å; Y95-A97 PolarHBondContact O-N 3.02Å; A97-C100 PolarHBondContact O-N 3.42Å; A97-T101 WeakPolarHBondContact O-CG2 3.27Å; A97-T101 PolarHBondContact O-N 2.67Å; A97-T101 PolarHBondContact O-OG1 3.01Å
98A98.7Very high97.8Very high0 Ų013.2 Ų13.20%07%0.074CC..Hα-helixtrans-60.9-46.917400000110.9I60 N94 Y95 A96 T101 G102 K158 A162I60-A98 HydrophobicContact CD1-CB 3.65Å; N94-A98 PolarHBondContact O-N 2.89Å; Y95-A98 WeakPolarHBondContact O-CA 3.37Å; Y95-A98 VanDerWaalsContact O-CB 3.27Å; Y95-A98 WeakPolarHBondContact O-CB 3.44Å; Y95-A98 PolarHBondContact O-N 2.86Å; A96-A98 VanDerWaalsContact C-N 3.33Å; A96-A98 PolarHBondContact O-N 3.42Å; A98-T101 PolarHBondContact O-N 2.82Å; A98-T101 PolarHBondContact O-OG1 3.15Å; A98-G102 PolarHBondContact O-N 3.38Å; A98-K158 HydrophobicContact CB-CB 4.18Å; A98-K158 WeakPolarHBondContact CB-O 3.4Å; A98-A162 HydrophobicContact CB-CB 4.4Å; A98-A162 VanDerWaalsContact O-CA 3.25Å; A98-A162 WeakPolarHBondContact O-CA 3.37Å; A98-A162 WeakPolarHBondContact O-CB 3.32Å
99Y98.8Very high97.9Very high0 Ų013.2 Ų13.20%07%0.074CC..Hα-helixtrans-55.6-51.9173.1-179.4-87.9000111.9Y95 A96 T101 G102 L103 V125 G161 K164 G165 D168 I199 H244Y95-Y99 PolarHBondContact O-N 3.13Å; A96-Y99 WeakPolarHBondContact O-CB 3.23Å; A96-Y99 PolarHBondContact O-N 2.88Å; Y99-T101 VanDerWaalsContact C-N 3.32Å; Y99-T101 PolarHBondContact O-N 3.26Å; Y99-G102 PolarHBondContact O-N 3.2Å; Y99-L103 HydrophobicContact CE1-CD2 4.35Å; Y99-L103 PolarHBondContact O-N 3.36Å; Y99-V125 HydrophobicContact CE1-CG2 4.31Å; Y99-V125 WeakPolarHBondContact OH-CG2 3.49Å; Y99-G161 VanDerWaalsContact CA-O 3.3Å; Y99-G161 WeakPolarHBondContact CA-O 3.49Å; Y99-K164 HydrophobicContact CD2-CB 4.27Å; Y99-K164 HydrophobicContact CD2-CG 4.22Å; Y99-K164 HydrophobicContact CE2-CB 4.4Å; Y99-K164 HydrophobicContact CE2-CG 3.92Å; Y99-G165 VanDerWaalsContact CD2-CA 3.47Å; Y99-G165 VanDerWaalsContact CE2-CA 3.49Å; Y99-D168 HydrophobicContact CE2-CB 4.41Å; Y99-D168 VanDerWaalsContact CE2-OD2 3.23Å; Y99-D168 WeakPolarHBondContact CE2-OD2 3.48Å; Y99-D168 VanDerWaalsContact OH-CB 3.32Å; Y99-D168 WeakPolarHBondContact OH-CB 3.31Å; Y99-D168 PolarHBondContact OH-OD2 3.15Å; Y99-I199 HydrophobicContact CD1-CG2 3.58Å; Y99-I199 HydrophobicContact CD2-CB 4.48Å; Y99-I199 HydrophobicContact CD2-CD1 4.15Å; Y99-I199 HydrophobicContact CD2-CG1 3.97Å; Y99-I199 HydrophobicContact CD2-CG2 3.72Å; Y99-I199 HydrophobicContact CE1-CG2 3.76Å; Y99-I199 HydrophobicContact CE2-CD1 4.01Å; Y99-I199 HydrophobicContact CE2-CG1 4.3Å; Y99-I199 HydrophobicContact CE2-CG2 3.86Å; Y99-I199 HydrophobicContact CG-CG1 4.46Å; Y99-I199 HydrophobicContact CG-CG2 3.57Å; Y99-H244 AromaticContact CD1-CE1 3.89Å; Y99-H244 AromaticContact CD1-NE2 3.48Å; Y99-H244 WeakPolarHBondContact CD1-NE2 3.3Å; Y99-H244 AromaticContact CE1-CE1 3.65Å; Y99-H244 AromaticContact CE1-NE2 3.59Å
100C98.6Very high98.1Very high0 Ų09 Ų90%05%0.051CC..Hα-helixtrans-57.4-41.8177.7-66.40000112.6L83 I88 A96 A97 G102 L103 L104 H244 I247L83-C100 HydrophobicContact CD1-CB 3.98Å; L83-C100 HydrophobicContact CD2-CB 3.82Å; I88-C100 HydrophobicContact CD1-CB 4.06Å; I88-C100 VanDerWaalsContact CD1-SG 3.58Å; A96-C100 PolarHBondContact O-N 3.49Å; A96-C100 PolarHBondContact O-SG 2.68Å; A97-C100 PolarHBondContact O-N 3.42Å; C100-G102 VanDerWaalsContact C-N 3.34Å; C100-G102 PolarHBondContact O-N 3.34Å; C100-L103 PolarHBondContact O-N 2.91Å; C100-L104 VanDerWaalsContact O-CB 3.31Å; C100-L104 WeakPolarHBondContact O-CB 3.3Å; C100-L104 PolarHBondContact O-N 2.99Å; C100-H244 VanDerWaalsContact SG-CD2 3.57Å; C100-H244 PolarHBondContact SG-NE2 2.97Å; C100-H244 VanDerWaalsContact SG-NE2 3.38Å; C100-I247 HydrophobicContact CB-CD1 4.08Å
101T98.7Very high98.1Very high0 Ų012.9 Ų12.90%07%0.069CC..Hα-helixtrans-66.2-35.3176.756.80000113.3I60 S80 L83 A97 A98 Y99 L105I60-T101 HydrophobicContact CB-CG2 4.26Å; I60-T101 HydrophobicContact CG2-CG2 4.28Å; I60-T101 WeakPolarHBondContact CG2-OG1 2.97Å; S80-T101 VanDerWaalsContact CA-CG2 3.48Å; L83-T101 HydrophobicContact CD1-CG2 3.89Å; L83-T101 HydrophobicContact CD2-CG2 4.49Å; L83-T101 HydrophobicContact CG-CG2 4.26Å; A97-T101 WeakPolarHBondContact O-CG2 3.27Å; A97-T101 PolarHBondContact O-N 2.67Å; A97-T101 PolarHBondContact O-OG1 3.01Å; A98-T101 PolarHBondContact O-N 2.82Å; A98-T101 PolarHBondContact O-OG1 3.15Å; Y99-T101 VanDerWaalsContact C-N 3.32Å; Y99-T101 PolarHBondContact O-N 3.26Å; T101-L105 WeakPolarHBondContact O-CB 3.47Å; T101-L105 PolarHBondContact O-N 2.91Å; T101-L105 VanDerWaalsContact O-N 3.08Å
102G98.6Very high98.2Very high0 Ų017.8 Ų17.80%08%0.084CC..Hα-helixtrans-65.7-47.6173.800000111.8A98 Y99 C100 L104 L105 A106 A162A98-G102 PolarHBondContact O-N 3.38Å; Y99-G102 PolarHBondContact O-N 3.2Å; C100-G102 VanDerWaalsContact C-N 3.34Å; C100-G102 PolarHBondContact O-N 3.34Å; G102-L104 PolarHBondContact O-N 2.89Å; G102-L105 PolarHBondContact O-N 3.41Å; G102-A106 PolarHBondContact O-N 3.3Å; G102-A162 WeakPolarHBondContact CA-O 3.47Å
103L98.6Very high98.2Very high0 Ų020.1 Ų20.10%09%0.093CC..Hα-helixtrans-58.6-47.2176.2179.162.5000111.3Y99 C100 L105 A106 R107 G165 H244 I247Y99-L103 HydrophobicContact CE1-CD2 4.35Å; Y99-L103 PolarHBondContact O-N 3.36Å; C100-L103 PolarHBondContact O-N 2.91Å; L103-L105 VanDerWaalsContact C-N 3.33Å; L103-L105 PolarHBondContact O-N 3.44Å; L103-A106 PolarHBondContact O-N 3.11Å; L103-R107 HydrophobicContact CD1-CG 4.13Å; L103-R107 WeakPolarHBondContact O-CG 3.48Å; L103-R107 PolarHBondContact O-N 3.13Å; L103-G165 WeakPolarHBondContact CA-O 3.3Å; L103-G165 PolarHBondContact N-O 2.85Å; L103-H244 HydrophobicContact CD2-CB 4.09Å; L103-I247 HydrophobicContact CD2-CG2 4.34Å; L103-I247 HydrophobicContact CG-CG2 4.02Å
104L98.6Very high98Very high0 Ų021 Ų210%011%0.11CC..Hα-helixtrans-59.3-43.4177.1177.959.8000112.1A78 L83 Y86 C100 G102 R108 I247 P251A78-L104 HydrophobicContact CB-CB 4.36Å; A78-L104 HydrophobicContact CB-CD2 4.15Å; A78-L104 HydrophobicContact CB-CG 4.07Å; L83-L104 HydrophobicContact CD2-CD2 4.38Å; Y86-L104 HydrophobicContact CD2-CD2 4.48Å; Y86-L104 HydrophobicContact CE2-CD1 3.94Å; Y86-L104 HydrophobicContact CE2-CD2 3.79Å; C100-L104 VanDerWaalsContact O-CB 3.31Å; C100-L104 WeakPolarHBondContact O-CB 3.3Å; C100-L104 PolarHBondContact O-N 2.99Å; G102-L104 PolarHBondContact O-N 2.89Å; L104-R108 WeakPolarHBondContact O-CB 3.42Å; L104-R108 PolarHBondContact O-N 3.05Å; L104-I247 HydrophobicContact CB-CD1 4.39Å; L104-I247 HydrophobicContact CB-CG2 3.96Å; L104-I247 HydrophobicContact CD1-CG1 4.46Å; L104-I247 HydrophobicContact CD1-CG2 3.97Å; L104-P251 HydrophobicContact CD1-CB 4.42Å
105L98.6Very high97.9Very high0 Ų020.8 Ų20.80%011%0.108CC..Hα-helixtrans-62.8-44.7177.5179.163.7000112L51 C62 I64 A78 T101 G102 L103 R108 L109L51-L105 HydrophobicContact CD1-CD2 3.27Å; C62-L105 HydrophobicContact CB-CB 4.44Å; C62-L105 HydrophobicContact CB-CD2 3.66Å; I64-L105 HydrophobicContact CD1-CD2 4.32Å; I64-L105 HydrophobicContact CG1-CD1 4.26Å; I64-L105 HydrophobicContact CG1-CD2 4.01Å; I64-L105 HydrophobicContact CG1-CG 4.12Å; A78-L105 HydrophobicContact CB-CB 3.81Å; A78-L105 HydrophobicContact CB-CD1 4.36Å; T101-L105 WeakPolarHBondContact O-CB 3.47Å; T101-L105 PolarHBondContact O-N 2.91Å; T101-L105 VanDerWaalsContact O-N 3.08Å; G102-L105 PolarHBondContact O-N 3.41Å; L103-L105 VanDerWaalsContact C-N 3.33Å; L103-L105 PolarHBondContact O-N 3.44Å; L105-R108 PolarHBondContact O-N 2.79Å; L105-L109 WeakPolarHBondContact O-CB 3.39Å; L105-L109 PolarHBondContact O-N 3.31Å
106A98.4Very high97.7Very high0 Ų022 Ų220%012%0.115CC..Hα-helixtrans-62.2-53.5179.400000111.6G102 L103 R108 L109 L110 A166 L171G102-A106 PolarHBondContact O-N 3.3Å; L103-A106 PolarHBondContact O-N 3.11Å; A106-R108 VanDerWaalsContact C-N 3.3Å; A106-R108 PolarHBondContact O-N 2.92Å; A106-L109 WeakPolarHBondContact O-CB 3.46Å; A106-L109 PolarHBondContact O-N 3.29Å; A106-L109 VanDerWaalsContact O-N 3.11Å; A106-L110 WeakPolarHBondContact O-CG 3.39Å; A106-L110 PolarHBondContact O-N 3Å; A106-A166 HydrophobicContact CB-CB 4.49Å; A106-A166 WeakPolarHBondContact CB-O 3.22Å; A106-L171 HydrophobicContact CB-CD1 3.99Å; A106-L171 HydrophobicContact CB-CD2 4.33Å; A106-L171 HydrophobicContact CB-CG 3.7Å
107R98.4Very high97.4Very high20 Ų2029.6 Ų29.68%0.07515%0.151CC..Hα-helixtrans-60-39.7178.2-62.9-49.7-61.4168.7-5.1112.1L103 L109 L110 H111 D116 Y119 E120 G169 I247 R248 P251L103-R107 HydrophobicContact CD1-CG 4.13Å; L103-R107 WeakPolarHBondContact O-CG 3.48Å; L103-R107 PolarHBondContact O-N 3.13Å; R107-L109 PolarHBondContact O-N 3.34Å; R107-L110 PolarHBondContact O-N 3.38Å; R107-H111 VanDerWaalsContact O-CB 3.24Å; R107-H111 WeakPolarHBondContact O-CB 3.37Å; R107-H111 PolarHBondContact O-N 3.4Å; R107-D116 PolarHBondContact NH1-O 2.87Å; R107-D116 PolarHBondContact NH2-O 3.16Å; R107-Y119 PolarHBondContact NH1-O 2.98Å; R107-E120 PolarHBondContact NH1-O 3.34Å; R107-G169 WeakPolarHBondContact CD-O 3.47Å; R107-I247 HydrophobicContact CG-CG2 4.49Å; R107-R248 HydrophobicContact CG-CG 4.36Å; R107-P251 HydrophobicContact CB-CB 3.7Å; R107-P251 HydrophobicContact CB-CG 4.15Å
108R98Very high97.3Very high19 Ų1932 Ų327%0.07217%0.165CC..Hα-helixtrans-65.1-38.2176.4-174.9178-66.7174.9-3.8112.6A77 E82 L104 L105 A106 K112 P251A77-R108 PolarHBondContact O-NH1 2.98Å; E82-R108 IonicContact OE1-NH1 3.71Å; E82-R108 IonicContact OE2-CZ 3.31Å; E82-R108 VanDerWaalsContact OE2-CZ 3.31Å; E82-R108 IonicContact OE2-NH1 2.88Å; E82-R108 PolarHBondContact OE2-NH1 2.98Å; E82-R108 IonicContact OE2-NH2 2.79Å; E82-R108 PolarHBondContact OE2-NH2 2.76Å; L104-R108 WeakPolarHBondContact O-CB 3.42Å; L104-R108 PolarHBondContact O-N 3.05Å; L105-R108 PolarHBondContact O-N 2.79Å; A106-R108 VanDerWaalsContact C-N 3.3Å; A106-R108 PolarHBondContact O-N 2.92Å; R108-K112 VanDerWaalsContact O-CB 3.32Å; R108-K112 WeakPolarHBondContact O-CB 2.98Å; R108-K112 PolarHBondContact O-N 2.96Å; R108-K112 VanDerWaalsContact O-N 3.15Å; R108-P251 HydrophobicContact CB-CB 4.24Å; R108-P251 PolarHBondContact NE-O 2.97Å; R108-P251 PolarHBondContact NH2-O 3.01Å
109L98.1Very high97.2Very high0 Ų032.4 Ų32.40%017%0.167CC..Hα-helixtrans-68.7-48.2177.5-174.177.4000111.3I64 V75 L105 A106 R107 K112 F113 F142 L171I64-L109 HydrophobicContact CB-CD1 4.34Å; I64-L109 HydrophobicContact CG1-CD1 4.41Å; I64-L109 HydrophobicContact CG1-CD2 4.06Å; I64-L109 HydrophobicContact CG2-CD1 4.31Å; I64-L109 HydrophobicContact CG2-CD2 4.47Å; V75-L109 HydrophobicContact CB-CD1 4.25Å; V75-L109 HydrophobicContact CG1-CD1 3.58Å; L105-L109 WeakPolarHBondContact O-CB 3.39Å; L105-L109 PolarHBondContact O-N 3.31Å; A106-L109 WeakPolarHBondContact O-CB 3.46Å; A106-L109 PolarHBondContact O-N 3.29Å; A106-L109 VanDerWaalsContact O-N 3.11Å; R107-L109 PolarHBondContact O-N 3.34Å; L109-K112 WeakPolarHBondContact O-CB 3.15Å; L109-K112 PolarHBondContact O-N 3.45Å; L109-F113 HydrophobicContact CD1-CD2 4.23Å; L109-F113 HydrophobicContact CD1-CE2 3.69Å; L109-F113 HydrophobicContact CD1-CZ 4.46Å; L109-F113 HydrophobicContact CG-CD2 4.06Å; L109-F113 HydrophobicContact CG-CE2 3.96Å; L109-F113 PolarHBondContact O-N 3.13Å; L109-F113 VanDerWaalsContact O-N 3.15Å; L109-F142 HydrophobicContact CD2-CD1 3.48Å; L109-F142 VanDerWaalsContact CD2-CD1 3.48Å; L109-F142 HydrophobicContact CD2-CD2 4.1Å; L109-F142 HydrophobicContact CD2-CE1 3.49Å; L109-F142 VanDerWaalsContact CD2-CE1 3.49Å; L109-F142 HydrophobicContact CD2-CE2 4.12Å; L109-F142 HydrophobicContact CD2-CG 3.79Å; L109-F142 HydrophobicContact CD2-CZ 3.82Å; L109-L171 HydrophobicContact CD2-CD1 4.24Å; L109-L171 HydrophobicContact CD2-CD2 3.75Å
110L97.6Very high97Very high0 Ų037.5 Ų37.50%019%0.191CC..Hα-helixtrans-65-42.8-178.9-66.5177000111.4A106 R107 K112 F113 G114 M115 D116 Y119 F142 G169 L171A106-L110 WeakPolarHBondContact O-CG 3.39Å; A106-L110 PolarHBondContact O-N 3Å; R107-L110 PolarHBondContact O-N 3.38Å; L110-K112 VanDerWaalsContact C-N 3.3Å; L110-K112 PolarHBondContact O-N 3.34Å; L110-F113 CarbonylContact O-C 3.5Å; L110-F113 PolarHBondContact O-N 2.88Å; L110-F113 VanDerWaalsContact O-N 3.07Å; L110-G114 PolarHBondContact O-N 2.98Å; L110-M115 HydrophobicContact CD2-CB 4.12Å; L110-M115 HydrophobicContact CD2-CE 4.09Å; L110-M115 PolarHBondContact O-N 2.94Å; L110-D116 HydrophobicContact CB-CB 4.02Å; L110-Y119 WeakPolarHBondContact CD1-O 3.46Å; L110-F142 HydrophobicContact CD2-CB 4.38Å; L110-G169 WeakPolarHBondContact CD1-O 3.49Å; L110-L171 HydrophobicContact CD2-CD2 4.08Å; L110-L171 HydrophobicContact CG-CD2 4.14Å
111H97.3Very high96.8Very high90 Ų9038.6 Ų38.642%0.41720%0.202SC..Hα-helixtrans-60.1-40.5174179.2-75.2000111.5R107 F113 G114 D116 P251R107-H111 VanDerWaalsContact O-CB 3.24Å; R107-H111 WeakPolarHBondContact O-CB 3.37Å; R107-H111 PolarHBondContact O-N 3.4Å; H111-F113 PolarHBondContact O-N 3.33Å; H111-G114 PolarHBondContact O-N 3.38Å; H111-D116 HydrophobicContact CB-CB 4.4Å; H111-D116 IonicContact CD2-OD2 3.91Å; H111-P251 HydrophobicContact CB-CG 4.01Å
112K96.5Very high96.6Very high127 Ų12739.9 Ų39.955%0.55221%0.208SC*.Hα-helixtrans-63.3-28.5176.6178.8174.1176.4173.70113V75 R108 L109 L110V75-K112 PolarHBondContact O-NZ 3.14Å; R108-K112 VanDerWaalsContact O-CB 3.32Å; R108-K112 WeakPolarHBondContact O-CB 2.98Å; R108-K112 PolarHBondContact O-N 2.96Å; R108-K112 VanDerWaalsContact O-N 3.15Å; L109-K112 WeakPolarHBondContact O-CB 3.15Å; L109-K112 PolarHBondContact O-N 3.45Å; L110-K112 VanDerWaalsContact C-N 3.3Å; L110-K112 PolarHBondContact O-N 3.34Å
113F96.6Very high96.4Very high85 Ų8543.9 Ų43.937%0.37323%0.232SC..Hα-helixtrans-100.61.7177.8-67.3-43.8000114V75 L109 L110 H111 M115 F142V75-F113 HydrophobicContact CG1-CE2 4.07Å; V75-F113 HydrophobicContact CG1-CZ 3.62Å; L109-F113 HydrophobicContact CD1-CD2 4.23Å; L109-F113 HydrophobicContact CD1-CE2 3.69Å; L109-F113 HydrophobicContact CD1-CZ 4.46Å; L109-F113 HydrophobicContact CG-CD2 4.06Å; L109-F113 HydrophobicContact CG-CE2 3.96Å; L109-F113 PolarHBondContact O-N 3.13Å; L109-F113 VanDerWaalsContact O-N 3.15Å; L110-F113 CarbonylContact O-C 3.5Å; L110-F113 PolarHBondContact O-N 2.88Å; L110-F113 VanDerWaalsContact O-N 3.07Å; H111-F113 PolarHBondContact O-N 3.33Å; F113-M115 VanDerWaalsContact C-N 3.32Å; F113-M115 HydrophobicContact CB-CE 3.74Å; F113-M115 HydrophobicContact CB-CG 4.36Å; F113-M115 HydrophobicContact CD2-CE 4.09Å; F113-M115 HydrophobicContact CG-CE 4.32Å; F113-M115 PolarHBondContact O-N 2.69Å; F113-F142 HydrophobicContact CD2-CD2 4.19Å; F113-F142 HydrophobicContact CD2-CE2 4.26Å; F113-F142 AromaticContact CE2-CD2 3.98Å; F113-F142 HydrophobicContact CE2-CD2 3.98Å; F113-F142 AromaticContact CE2-CE2 3.59Å; F113-F142 HydrophobicContact CE2-CE2 3.59Å; F113-F142 HydrophobicContact CE2-CZ 4.43Å; F113-F142 HydrophobicContact CZ-CE2 4.45Å
114G95.8Very high96.1Very high59 Ų5951.4 Ų51.461%0.60827%0.267SS*.THydrogen-bonded Turntrans65.830-178.900000114.2L110 H111L110-G114 PolarHBondContact O-N 2.98Å; H111-G114 PolarHBondContact O-N 3.38Å
115M95.3Very high95.8Very high22 Ų2252 Ų5211%0.10827%0.271CS..  trans-114.110.6-179.2-60.2-172.4-66.400112.8L110 F113 V118 Y119 P139 F142L110-M115 HydrophobicContact CD2-CB 4.12Å; L110-M115 HydrophobicContact CD2-CE 4.09Å; L110-M115 PolarHBondContact O-N 2.94Å; F113-M115 VanDerWaalsContact C-N 3.32Å; F113-M115 HydrophobicContact CB-CE 3.74Å; F113-M115 HydrophobicContact CB-CG 4.36Å; F113-M115 HydrophobicContact CD2-CE 4.09Å; F113-M115 HydrophobicContact CG-CE 4.32Å; F113-M115 PolarHBondContact O-N 2.69Å; M115-V118 PolarHBondContact O-N 2.96Å; M115-Y119 HydrophobicContact CB-CD2 4.28Å; M115-Y119 PolarHBondContact O-N 2.83Å; M115-Y119 VanDerWaalsContact O-N 3.09Å; M115-P139 HydrophobicContact SD-CB 3.96Å; M115-F142 HydrophobicContact CE-CB 4.25Å; M115-F142 HydrophobicContact CE-CD2 4.42Å
116D93Very high95.5Very high38 Ų3855 Ų5520%0.20329%0.29CS..THydrogen-bonded Turntrans-71.6-29-173.257.6-50.3000113.8R107 L110 H111R107-D116 PolarHBondContact NH1-O 2.87Å; R107-D116 PolarHBondContact NH2-O 3.16Å; L110-D116 HydrophobicContact CB-CB 4.02Å; H111-D116 HydrophobicContact CB-CB 4.4Å; H111-D116 IonicContact CD2-OD2 3.91Å
117Q93.9Very high95.2Very high161 Ų16155 Ų5575%0.75229%0.29SS*.THydrogen-bonded Turntrans-79.3-33.1174.1-63.4-179-2.500112.7
118V95Very high95Very high51 Ų5157.9 Ų57.931%0.30931%0.306SS..THydrogen-bonded Turntrans-73.8-43.7179.3-179.20000110.4M115 Q138M115-V118 PolarHBondContact O-N 2.96Å; V118-Q138 HydrophobicContact CG1-CB 3.87Å; V118-Q138 HydrophobicContact CG1-CG 4.02Å; V118-Q138 HydrophobicContact CG2-CG 4.49Å
119Y96.4Very high94.8Very high8 Ų861.4 Ų61.43%0.03132%0.324CS..  trans-114.374-177.2-60.8-63.5000110.6R107 L110 M115 G121 V132 E133 S134 V135 P139 A141R107-Y119 PolarHBondContact NH1-O 2.98Å; L110-Y119 WeakPolarHBondContact CD1-O 3.46Å; M115-Y119 HydrophobicContact CB-CD2 4.28Å; M115-Y119 PolarHBondContact O-N 2.83Å; M115-Y119 VanDerWaalsContact O-N 3.09Å; Y119-G121 PolarHBondContact O-N 3.19Å; Y119-V132 HydrophobicContact CD1-CG1 3.51Å; Y119-V132 HydrophobicContact CE1-CG1 4.02Å; Y119-V132 HydrophobicContact CG-CG1 4.28Å; Y119-E133 WeakPolarHBondContact CE1-O 3.3Å; Y119-S134 WeakPolarHBondContact OH-CA 3.49Å; Y119-V135 HydrophobicContact CE1-CG2 4.08Å; Y119-V135 PolarHBondContact OH-N 2.96Å; Y119-P139 WeakPolarHBondContact CE2-O 3.02Å; Y119-P139 PolarHBondContact OH-O 2.88Å; Y119-A141 HydrophobicContact CD1-CB 4.36Å; Y119-A141 HydrophobicContact CE1-CB 3.94Å; Y119-A141 HydrophobicContact CE2-CB 4.26Å; Y119-A141 PolarHBondContact OH-N 3.3Å; Y119-A141 VanDerWaalsContact OH-N 3.16Å
120E94.9Very high94.6Very high107 Ų10764.2 Ų64.250%0.534%0.336SS..  trans-66.3-27.4176.5-62.4-167.6165.800112.7R107R107-E120 PolarHBondContact NH1-O 3.34Å
121G94.7Very high94.4Very high23 Ų2367.5 Ų67.524%0.23735%0.354CS..  trans74.4-149.2-174.600000111.4Y119 D168Y119-G121 PolarHBondContact O-N 3.19Å; G121-D168 CarbonylContact C-O 3.46Å; G121-D168 WeakPolarHBondContact CA-O 3.22Å
122Q94.8Very high94.2Very high27 Ų2764.2 Ų64.213%0.12634%0.34CS..  trans-97.5101.7-175.9-168-179.9-800110.5E124 T126 F130 D168 R248Q122-E124 VanDerWaalsContact CG-O 3.28Å; Q122-E124 WeakPolarHBondContact CG-O 3.31Å; Q122-E124 PolarHBondContact NE2-O 3.28Å; Q122-T126 PolarHBondContact NE2-OG1 3.26Å; Q122-F130 HydrophobicContact CB-CD1 3.99Å; Q122-F130 HydrophobicContact CB-CD2 4.45Å; Q122-F130 HydrophobicContact CB-CE1 4.09Å; Q122-F130 HydrophobicContact CB-CG 4.18Å; Q122-F130 HydrophobicContact CB-CZ 4.38Å; Q122-D168 HydrophobicContact CB-CB 4.26Å; Q122-D168 PolarHBondContact N-O 2.97Å; Q122-R248 PolarHBondContact O-NH2 3.22Å
123V93.2Very high94.1Very high84 Ų8465.9 Ų65.951%0.50935%0.349SS..SBendtrans-63.1-50.3-177.1-178.90000111.4R248V123-R248 PolarHBondContact O-NH1 3.32Å
124E92.2Very high94Very high158 Ų15865.4 Ų65.474%0.73836%0.357SS*.SBendtrans-92.8119177.8-63.4-167.7169.100111.7Q122 T126Q122-E124 VanDerWaalsContact CG-O 3.28Å; Q122-E124 WeakPolarHBondContact CG-O 3.31Å; Q122-E124 PolarHBondContact NE2-O 3.28Å; E124-T126 PolarHBondContact O-N 2.86Å; E124-T126 VanDerWaalsContact O-N 3.15Å
125V93.6Very high93.8Very high12 Ų1266.1 Ų66.17%0.07335%0.349CS..  trans-75.8106.5-176.7-175.40000110.5Y99 R196 I199 M200Y99-V125 HydrophobicContact CE1-CG2 4.31Å; Y99-V125 WeakPolarHBondContact OH-CG2 3.49Å; V125-R196 WeakPolarHBondContact O-CD 3.27Å; V125-R196 PolarHBondContact O-NE 3.48Å; V125-I199 HydrophobicContact CG1-CB 4.3Å; V125-I199 HydrophobicContact CG1-CD1 3.84Å; V125-I199 HydrophobicContact CG1-CG2 3.78Å; V125-M200 HydrophobicContact CB-CE 3.67Å; V125-M200 HydrophobicContact CG1-CE 4.17Å; V125-M200 HydrophobicContact CG2-CE 4.04Å
126T92.5Very high93.7Very high65 Ų6572.8 Ų72.840%0.39939%0.385SS..  trans-91.6-24.1173.763.90000113Q122 E124 D128 R196Q122-T126 PolarHBondContact NE2-OG1 3.26Å; E124-T126 PolarHBondContact O-N 2.86Å; E124-T126 VanDerWaalsContact O-N 3.15Å; T126-D128 VanDerWaalsContact C-N 3.25Å; T126-D128 PolarHBondContact OG1-N 3.21Å; T126-R196 WeakPolarHBondContact O-CB 3.42Å
127G91.7Very high93.7Very high0 Ų074.9 Ų74.90%042%0.416CS..  trans82.3-1.9-172.600000114.2F190 H195G127-F190 WeakPolarHBondContact O-CE1 3.38Å; G127-F190 WeakPolarHBondContact O-CZ 3.3Å; G127-H195 PolarHBondContact O-ND1 3.39Å
128D94.4Very high93.8Very high80 Ų8072.2 Ų72.243%0.42840%0.404SS..SBendtrans-82.5175.5-178.6-155.51.8000112.9T126 F130 K164 A192T126-D128 VanDerWaalsContact C-N 3.25Å; T126-D128 PolarHBondContact OG1-N 3.21Å; D128-F130 PolarHBondContact O-N 2.94Å; D128-K164 VanDerWaalsContact O-CE 3.3Å; D128-K164 WeakPolarHBondContact O-CE 3.45Å; D128-K164 PolarHBondContact O-NZ 2.9Å; D128-A192 HydrophobicContact CB-CB 4.03Å
129E93.3Very high93.8Very high93 Ų9373.2 Ų73.244%0.43541%0.411SS..  trans-60.9130.9171-166.3156.3-164.800111.2N131 L177E129-N131 PolarHBondContact OE1-ND2 3.45Å; E129-L177 HydrophobicContact CB-CD1 3.99Å; E129-L177 HydrophobicContact CB-CD2 3.65Å; E129-L177 HydrophobicContact CB-CG 4.07Å; E129-L177 HydrophobicContact CG-CD2 4.11Å; E129-L177 HydrophobicContact CG-CG 4.36Å
130F94.1Very high93.7Very high58 Ų5875 Ų7525%0.25443%0.432SS..  trans-144.9129.1174.1175.6-107.7000107.3Q122 D128 V132 V167 H175Q122-F130 HydrophobicContact CB-CD1 3.99Å; Q122-F130 HydrophobicContact CB-CD2 4.45Å; Q122-F130 HydrophobicContact CB-CE1 4.09Å; Q122-F130 HydrophobicContact CB-CG 4.18Å; Q122-F130 HydrophobicContact CB-CZ 4.38Å; D128-F130 PolarHBondContact O-N 2.94Å; F130-V132 HydrophobicContact CD1-CG2 4.35Å; F130-V132 HydrophobicContact CE1-CG2 3.43Å; F130-V132 VanDerWaalsContact CE1-CG2 3.43Å; F130-V132 HydrophobicContact CZ-CG2 3.8Å; F130-V167 HydrophobicContact CD1-CG1 4.12Å; F130-V167 WeakPolarHBondContact O-CG1 3.42Å; F130-H175 PolarHBondContact O-CE1 3.48Å
131N93.9Very high93.8Very high70 Ų7070.3 Ų70.337%0.37441%0.411SS..  trans-131.3127.8175-69.5-64.9000107.7E129 E133 H175E129-N131 PolarHBondContact OE1-ND2 3.45Å; N131-E133 PolarHBondContact O-N 3.05Å; N131-H175 PolarHBondContact OD1-CE1 3.39Å; N131-H175 PolarHBondContact OD1-ND1 3.33Å
132V93.4Very high94Very high20 Ų2070 Ų7012%0.12140%0.404CS..PPolyproline II helixtrans-76.5122.1179.2178.50000109.1Y119 F130 A141Y119-V132 HydrophobicContact CD1-CG1 3.51Å; Y119-V132 HydrophobicContact CE1-CG1 4.02Å; Y119-V132 HydrophobicContact CG-CG1 4.28Å; F130-V132 HydrophobicContact CD1-CG2 4.35Å; F130-V132 HydrophobicContact CE1-CG2 3.43Å; F130-V132 VanDerWaalsContact CE1-CG2 3.43Å; F130-V132 HydrophobicContact CZ-CG2 3.8Å; V132-A141 HydrophobicContact CG1-CB 3.9Å
133E93.1Very high94.1Very high162 Ų16272.2 Ų72.276%0.75742%0.419SS*.PPolyproline II helixtrans-92.7155.2171.9-62.4-171168.200110.8Y119 N131Y119-E133 WeakPolarHBondContact CE1-O 3.3Å; N131-E133 PolarHBondContact O-N 3.05Å
134S93.9Very high94.3Very high75 Ų7568.2 Ų68.252%0.52439%0.394SS..PPolyproline II helixtrans-76.8144.3175.7-62.80000109.9Y119 A141Y119-S134 WeakPolarHBondContact OH-CA 3.49Å; S134-A141 PolarHBondContact OG-N 3.06Å; S134-A141 VanDerWaalsContact OG-N 3.07Å
135V93.6Very high94.6Very high74 Ų7464.9 Ų64.945%0.44838%0.376SS..PPolyproline II helixtrans-98.7130.3-178.9178.70000107.6Y119 G137 Q138Y119-V135 HydrophobicContact CE1-CG2 4.08Å; Y119-V135 PolarHBondContact OH-N 2.96Å; V135-G137 PolarHBondContact O-N 2.97Å; V135-Q138 HydrophobicContact CB-CB 4.24Å; V135-Q138 HydrophobicContact CB-CG 4.34Å; V135-Q138 HydrophobicContact CG1-CG 4.14Å; V135-Q138 PolarHBondContact O-N 3.3Å; V135-Q138 VanDerWaalsContact O-N 3.16Å
136D92.9Very high94.9Very high162 Ų16266.1 Ų66.187%0.86638%0.382SS*.THydrogen-bonded Turntrans-60.2136-179.8-70.4-26.4000111.4Q138D136-Q138 PolarHBondContact O-N 2.71Å
137G92.6Very high95.2Very high83 Ų8363.9 Ų63.986%0.85637%0.367SS*.THydrogen-bonded Turntrans77.8-3.2-177.800000115.4V135V135-G137 PolarHBondContact O-N 2.97Å
138Q95Very high95.4Very high105 Ų10564.7 Ų64.749%0.49137%0.374SS..SBendtrans-108.8163173.7-63.7-63-25.700111.5V118 V135 D136 G140V118-Q138 HydrophobicContact CG1-CB 3.87Å; V118-Q138 HydrophobicContact CG1-CG 4.02Å; V118-Q138 HydrophobicContact CG2-CG 4.49Å; V135-Q138 HydrophobicContact CB-CB 4.24Å; V135-Q138 HydrophobicContact CB-CG 4.34Å; V135-Q138 HydrophobicContact CG1-CG 4.14Å; V135-Q138 PolarHBondContact O-N 3.3Å; V135-Q138 VanDerWaalsContact O-N 3.16Å; D136-Q138 PolarHBondContact O-N 2.71Å; Q138-G140 PolarHBondContact O-N 3.27Å
139P94.6Very high95.6Very high72 Ų7262.2 Ų62.247%0.46837%0.367SS..PPolyproline II helixtrans-57134.5171.1-22.533.7000110.3M115 Y119M115-P139 HydrophobicContact SD-CB 3.96Å; Y119-P139 WeakPolarHBondContact CE2-O 3.02Å; Y119-P139 PolarHBondContact OH-O 2.88Å
140G95.4Very high95.8Very high45 Ų4562.1 Ų62.146%0.46437%0.369SS..PPolyproline II helixtrans-61.5153.3-177.900000113.9Q138Q138-G140 PolarHBondContact O-N 3.27Å
141A96.9Very high95.9Very high8 Ų861.3 Ų61.37%0.06637%0.373CS..PPolyproline II helixtrans-59.1139.4-177.900000111.8Y119 V132 S134 T143 A172Y119-A141 HydrophobicContact CD1-CB 4.36Å; Y119-A141 HydrophobicContact CE1-CB 3.94Å; Y119-A141 HydrophobicContact CE2-CB 4.26Å; Y119-A141 PolarHBondContact OH-N 3.3Å; Y119-A141 VanDerWaalsContact OH-N 3.16Å; V132-A141 HydrophobicContact CG1-CB 3.9Å; S134-A141 PolarHBondContact OG-N 3.06Å; S134-A141 VanDerWaalsContact OG-N 3.07Å; A141-T143 PolarHBondContact O-N 3.13Å; A141-T143 PolarHBondContact O-OG1 3.35Å; A141-A172 HydrophobicContact CB-CB 4.01Å
142F98.1Very high96.1Very high18 Ų1867.8 Ų67.88%0.07939%0.392CS..  trans-66.9109-176.3-172-85.1000110.8Y49 I64 L109 L110 F113 M115 C144 L171 A172Y49-F142 HydrophobicContact CD1-CE2 4.49Å; Y49-F142 AromaticContact CD1-CZ 3.69Å; Y49-F142 HydrophobicContact CD1-CZ 3.69Å; Y49-F142 HydrophobicContact CD2-CE1 4.14Å; Y49-F142 AromaticContact CD2-CE2 3.89Å; Y49-F142 HydrophobicContact CD2-CE2 3.89Å; Y49-F142 AromaticContact CD2-CZ 3.45Å; Y49-F142 HydrophobicContact CD2-CZ 3.45Å; Y49-F142 VanDerWaalsContact CD2-CZ 3.45Å; Y49-F142 HydrophobicContact CE1-CE2 4.39Å; Y49-F142 AromaticContact CE1-CZ 3.99Å; Y49-F142 HydrophobicContact CE1-CZ 3.99Å; Y49-F142 AromaticContact CE2-CE2 3.77Å; Y49-F142 HydrophobicContact CE2-CE2 3.77Å; Y49-F142 AromaticContact CE2-CZ 3.77Å; Y49-F142 HydrophobicContact CE2-CZ 3.77Å; Y49-F142 AromaticContact CG-CE1 3.98Å; Y49-F142 HydrophobicContact CG-CE1 3.98Å; Y49-F142 HydrophobicContact CG-CE2 4.25Å; Y49-F142 AromaticContact CG-CZ 3.4Å; Y49-F142 HydrophobicContact CG-CZ 3.4Å; I64-F142 HydrophobicContact CG2-CE1 3.98Å; I64-F142 HydrophobicContact CG2-CZ 3.95Å; L109-F142 HydrophobicContact CD2-CD1 3.48Å; L109-F142 VanDerWaalsContact CD2-CD1 3.48Å; L109-F142 HydrophobicContact CD2-CD2 4.1Å; L109-F142 HydrophobicContact CD2-CE1 3.49Å; L109-F142 VanDerWaalsContact CD2-CE1 3.49Å; L109-F142 HydrophobicContact CD2-CE2 4.12Å; L109-F142 HydrophobicContact CD2-CG 3.79Å; L109-F142 HydrophobicContact CD2-CZ 3.82Å; L110-F142 HydrophobicContact CD2-CB 4.38Å; F113-F142 HydrophobicContact CD2-CD2 4.19Å; F113-F142 HydrophobicContact CD2-CE2 4.26Å; F113-F142 AromaticContact CE2-CD2 3.98Å; F113-F142 HydrophobicContact CE2-CD2 3.98Å; F113-F142 AromaticContact CE2-CE2 3.59Å; F113-F142 HydrophobicContact CE2-CE2 3.59Å; F113-F142 HydrophobicContact CE2-CZ 4.43Å; F113-F142 HydrophobicContact CZ-CE2 4.45Å; M115-F142 HydrophobicContact CE-CB 4.25Å; M115-F142 HydrophobicContact CE-CD2 4.42Å; F142-C144 HydrophobicContact CD1-CB 4.3Å; F142-C144 HydrophobicContact CE1-CB 3.91Å; F142-L171 HydrophobicContact CB-CD2 4.03Å; F142-L171 HydrophobicContact CD1-CD2 4.1Å; F142-L171 HydrophobicContact CG-CD2 4.38Å; F142-A172 PolarHBondContact O-N 2.89Å
143T98Very high96.2Very high72 Ų7269.8 Ų69.844%0.44241%0.405SS..BIsolated β-bridgetrans-87.9128.2-178.2-57.80000111.5A141 A172A141-T143 PolarHBondContact O-N 3.13Å; A141-T143 PolarHBondContact O-OG1 3.35Å; T143-A172 WeakPolarHBondContact CA-O 3.37Å
144C97.9Very high96.4Very high0 Ų065.7 Ų65.70%039%0.391CS..  trans-148.2163.3171.875.30000113.2Y49 I64 F142 A172 I173 P174Y49-C144 WeakPolarHBondContact O-CA 3.45Å; I64-C144 HydrophobicContact CD1-CB 4.41Å; F142-C144 HydrophobicContact CD1-CB 4.3Å; F142-C144 HydrophobicContact CE1-CB 3.91Å; C144-A172 PolarHBondContact N-O 2.98Å; C144-I173 VanDerWaalsContact SG-CG1 3.59Å; C144-P174 WeakPolarHBondContact O-CD 3.44Å
145Y98.4Very high96.5Very high88 Ų8864.3 Ų64.335%0.34538%0.379SS..EExtended strand (participates in β ladder)trans-117.5141.6-175.6-52.2-75.6000112.2K48 Y49 R50 L51 D147 P174K48-Y145 HydrophobicContact CD-CE2 4.45Å; K48-Y145 HydrophobicContact CG-CD2 4.03Å; K48-Y145 HydrophobicContact CG-CE2 3.87Å; Y49-Y145 WeakPolarHBondContact O-CD2 3.46Å; Y49-Y145 PolarHBondContact O-N 3.47Å; R50-Y145 CarbonylContact C-O 3.57Å; R50-Y145 WeakPolarHBondContact CA-O 3.4Å; R50-Y145 WeakPolarHBondContact CB-O 3.34Å; L51-Y145 PolarHBondContact N-O 3.48Å; Y145-D147 PolarHBondContact O-N 3.46Å; Y145-P174 HydrophobicContact CD1-CG 3.78Å; Y145-P174 HydrophobicContact CE1-CG 3.89Å
146L98.6Very high96.6Very high39 Ų3962.2 Ų62.220%0.20437%0.373CS..EExtended strand (participates in β ladder)trans-67.7129.5178.5-175.966000112.3L51 V53 V159 F160 L163L51-L146 HydrophobicContact CD2-CD1 4.32Å; L51-L146 HydrophobicContact CG-CD1 4.39Å; V53-L146 HydrophobicContact CG2-CD1 3.81Å; L146-V159 HydrophobicContact CD1-CG1 4.06Å; L146-V159 HydrophobicContact CD2-CG1 4Å; L146-V159 HydrophobicContact CG-CG1 4.44Å; L146-F160 HydrophobicContact CD2-CD1 4.13Å; L146-F160 HydrophobicContact CD2-CE1 3.82Å; L146-L163 HydrophobicContact CB-CD1 3.85Å; L146-L163 HydrophobicContact CD1-CB 4.4Å; L146-L163 HydrophobicContact CD1-CD1 4.18Å; L146-L163 HydrophobicContact CD2-CD1 3.7Å; L146-L163 HydrophobicContact CG-CD1 4.1Å
147D98.4Very high96.8Very high17 Ų1756.1 Ų56.19%0.09134%0.34CS..EExtended strand (participates in β ladder)trans-109.696.4165.5-176-20.7000109.2L36 R50 L51 I52 V53 R54 Y145 G149L36-D147 HydrophobicContact CD2-CB 3.41Å; L36-D147 VanDerWaalsContact CD2-CB 3.41Å; R50-D147 HydrophobicContact CB-CB 4.41Å; L51-D147 PolarHBondContact O-N 2.95Å; I52-D147 HydrophobicContact CG1-CB 4.16Å; V53-D147 PolarHBondContact N-O 3.3Å; R54-D147 IonicContact CZ-OD1 3.12Å; R54-D147 PolarHBondContact NH1-O 3.06Å; R54-D147 IonicContact NH1-OD1 4Å; R54-D147 PolarHBondContact NH1-OD1 3.03Å; R54-D147 VanDerWaalsContact NH2-CG 3.31Å; R54-D147 IonicContact NH2-OD1 3.44Å; R54-D147 PolarHBondContact NH2-OD1 3.47Å; R54-D147 IonicContact NH2-OD2 2.77Å; R54-D147 PolarHBondContact NH2-OD2 2.82Å; Y145-D147 PolarHBondContact O-N 3.46Å; D147-G149 VanDerWaalsContact C-N 3.29Å; D147-G149 WeakPolarHBondContact OD1-CA 3.27Å; D147-G149 PolarHBondContact OD1-N 2.71Å
148A97.7Very high97.1Very high18 Ų1855.6 Ų55.615%0.14932%0.315CS..  trans-79.3-8.8175.100000113.7R54 L150 A151 T153 V159R54-A148 VanDerWaalsContact NH1-C 3.34Å; A148-L150 PolarHBondContact O-N 2.85Å; A148-A151 WeakPolarHBondContact O-CB 3.45Å; A148-A151 PolarHBondContact O-N 3.29Å; A148-T153 HydrophobicContact CB-CG2 3.85Å; A148-V159 HydrophobicContact CB-CG1 4Å
149G96.6Very high97.3Very high27 Ų2750.7 Ų50.728%0.27829%0.292SS..THydrogen-bonded Turntrans63.3-120.7-178.500000112.9D147D147-G149 VanDerWaalsContact C-N 3.29Å; D147-G149 WeakPolarHBondContact OD1-CA 3.27Å; D147-G149 PolarHBondContact OD1-N 2.71Å
150L97.6Very high97.4Very high91 Ų9148.3 Ų48.348%0.47627%0.274SS..THydrogen-bonded Turntrans-1012.8-179.8-64.2174.6000112.9G26 D29 A148 R152G26-L150 WeakPolarHBondContact O-CD1 3.28Å; D29-L150 HydrophobicContact CB-CD2 3.71Å; A148-L150 PolarHBondContact O-N 2.85Å; L150-R152 PolarHBondContact O-N 2.97Å
151A97.1Very high97.6Very high41 Ų4146.1 Ų46.134%0.33925%0.252SS..  trans-65.9132.6178.100000109.9A148 T153 V159A148-A151 WeakPolarHBondContact O-CB 3.45Å; A148-A151 PolarHBondContact O-N 3.29Å; A151-T153 PolarHBondContact O-N 3.08Å; A151-V159 HydrophobicContact CB-CG2 4.17Å
152R97.2Very high97.7Very high206 Ų20645.8 Ų45.878%0.77725%0.249SC*.  trans-69.9118.5171.7-173.7-177.1-74.7-92.8-1.1108.9L150 T154 N157L150-R152 PolarHBondContact O-N 2.97Å; R152-T154 VanDerWaalsContact C-N 3.26Å; R152-T154 HydrophobicContact CG-CG2 4.04Å; R152-T154 PolarHBondContact O-N 2.9Å; R152-N157 PolarHBondContact O-ND2 3.17Å
153T96.6Very high97.7Very high63 Ų6345.1 Ų45.139%0.38725%0.246SC..  trans-84.860-175.451.50000112.2A148 A151 F160A148-T153 HydrophobicContact CB-CG2 3.85Å; A151-T153 PolarHBondContact O-N 3.08Å; T153-F160 HydrophobicContact CG2-CE2 4.27Å; T153-F160 HydrophobicContact CG2-CZ 3.85Å
154T96.4Very high97.7Very high76 Ų7641.7 Ų41.747%0.46623%0.225SC..  trans-74.1161.4168.949.20000111.1R152 N157R152-T154 VanDerWaalsContact C-N 3.26Å; R152-T154 HydrophobicContact CG-CG2 4.04Å; R152-T154 PolarHBondContact O-N 2.9Å; T154-N157 WeakPolarHBondContact O-CB 3.44Å; T154-N157 PolarHBondContact O-N 2.68Å
155T96.7Very high97.7Very high45 Ų4541.7 Ų41.728%0.27623%0.225SC..THydrogen-bonded Turntrans-60137.9174.1-56.20000110.2N157 K178 R179 F180T155-N157 VanDerWaalsContact C-N 3.35Å; T155-N157 PolarHBondContact O-N 3.23Å; T155-K178 PolarHBondContact OG1-O 3.43Å; T155-K178 VanDerWaalsContact OG1-O 3.07Å; T155-R179 WeakPolarHBondContact CA-O 3.39Å; T155-R179 PolarHBondContact OG1-NH1 2.93Å; T155-F180 WeakPolarHBondContact CG2-O 3.47Å
156G95.4Very high97.7Very high31 Ų3137.5 Ų37.532%0.3221%0.209SC..THydrogen-bonded Turntrans823.9-177.900000115.5K158 R179G156-K158 PolarHBondContact O-N 3.45Å; G156-R179 PolarHBondContact N-O 3.45Å
157N98.1Very high97.7Very high33 Ų3335.6 Ų35.618%0.17620%0.199CC..  trans-65.8134.2178.1-167.9-42.5000111.3R152 T154 T155 V159 F160R152-N157 PolarHBondContact O-ND2 3.17Å; T154-N157 WeakPolarHBondContact O-CB 3.44Å; T154-N157 PolarHBondContact O-N 2.68Å; T155-N157 VanDerWaalsContact C-N 3.35Å; T155-N157 PolarHBondContact O-N 3.23Å; N157-V159 PolarHBondContact O-N 2.94Å; N157-V159 VanDerWaalsContact O-N 3.09Å; N157-V159 PolarHBondContact OD1-N 3.45Å; N157-F160 HydrophobicContact CB-CD2 3.9Å; N157-F160 HydrophobicContact CB-CE2 4.15Å; N157-F160 WeakPolarHBondContact O-CB 3.15Å; N157-F160 PolarHBondContact O-N 3.03Å
158K98.2Very high97.7Very high73 Ų7334.8 Ų34.832%0.31720%0.195SC..Hα-helixtrans-57.5-22.6178.3-65.5-179.2-70.5-1730114.5L55 T93 Y95 A98 G156 F160 G161 A162L55-K158 HydrophobicContact CD1-CB 3.78Å; L55-K158 HydrophobicContact CD2-CB 4.31Å; T93-K158 WeakPolarHBondContact O-CD 3.42Å; T93-K158 WeakPolarHBondContact O-CE 3.47Å; T93-K158 PolarHBondContact O-NZ 3.27Å; Y95-K158 HydrophobicContact CD2-CG 4.1Å; A98-K158 HydrophobicContact CB-CB 4.18Å; A98-K158 WeakPolarHBondContact CB-O 3.4Å; G156-K158 PolarHBondContact O-N 3.45Å; K158-F160 PolarHBondContact O-N 2.77Å; K158-G161 PolarHBondContact O-N 3.06Å; K158-A162 PolarHBondContact O-N 2.8Å
159V98.4Very high97.7Very high2 Ų234 Ų341%0.01219%0.188CC..Hα-helixtrans-55.4-37.5170.5171.30000110.9V53 L55 L146 A148 A151 N157 A162 L163V53-V159 HydrophobicContact CB-CG1 4.12Å; V53-V159 HydrophobicContact CG1-CB 4.42Å; V53-V159 HydrophobicContact CG1-CG1 4.28Å; V53-V159 HydrophobicContact CG1-CG2 4.24Å; L55-V159 HydrophobicContact CD1-CG2 3.89Å; L55-V159 HydrophobicContact CG-CG2 4.25Å; L146-V159 HydrophobicContact CD1-CG1 4.06Å; L146-V159 HydrophobicContact CD2-CG1 4Å; L146-V159 HydrophobicContact CG-CG1 4.44Å; A148-V159 HydrophobicContact CB-CG1 4Å; A151-V159 HydrophobicContact CB-CG2 4.17Å; N157-V159 PolarHBondContact O-N 2.94Å; N157-V159 VanDerWaalsContact O-N 3.09Å; N157-V159 PolarHBondContact OD1-N 3.45Å; V159-A162 PolarHBondContact O-N 2.98Å; V159-L163 PolarHBondContact O-N 3.23Å; V159-L163 VanDerWaalsContact O-N 3.13Å
160F98.6Very high97.7Very high21 Ų2132.7 Ų32.79%0.09217%0.174CC..Hα-helixtrans-75.8-27.5176.6-60.6-66.4000112.7L146 T153 N157 K158 A162 L163 K164 R179 F180L146-F160 HydrophobicContact CD2-CD1 4.13Å; L146-F160 HydrophobicContact CD2-CE1 3.82Å; T153-F160 HydrophobicContact CG2-CE2 4.27Å; T153-F160 HydrophobicContact CG2-CZ 3.85Å; N157-F160 HydrophobicContact CB-CD2 3.9Å; N157-F160 HydrophobicContact CB-CE2 4.15Å; N157-F160 WeakPolarHBondContact O-CB 3.15Å; N157-F160 PolarHBondContact O-N 3.03Å; K158-F160 PolarHBondContact O-N 2.77Å; F160-A162 VanDerWaalsContact C-N 3.34Å; F160-A162 PolarHBondContact O-N 3.06Å; F160-L163 WeakPolarHBondContact O-CB 3.19Å; F160-L163 PolarHBondContact O-N 3.39Å; F160-K164 PolarHBondContact O-N 3.44Å; F160-R179 HydrophobicContact CD1-CB 4.18Å; F160-R179 HydrophobicContact CD2-CB 3.75Å; F160-R179 HydrophobicContact CE1-CB 4.01Å; F160-R179 HydrophobicContact CE1-CG 4.42Å; F160-R179 HydrophobicContact CE2-CB 3.56Å; F160-R179 HydrophobicContact CE2-CG 4.09Å; F160-R179 HydrophobicContact CG-CB 4.06Å; F160-R179 HydrophobicContact CZ-CB 3.7Å; F160-R179 HydrophobicContact CZ-CG 3.91Å; F160-F180 HydrophobicContact CB-CD1 3.85Å; F160-F180 HydrophobicContact CB-CE1 3.81Å; F160-F180 WeakPolarHBondContact O-CE1 3.47Å
161G98.3Very high97.7Very high0 Ų028.3 Ų28.30%015%0.152CC..Hα-helixtrans-58.9-46.6169.500000111.7Y95 Y99 K158 L163 K164 G165Y95-G161 WeakPolarHBondContact OH-CA 3.44Å; Y95-G161 PolarHBondContact OH-N 3.05Å; Y99-G161 VanDerWaalsContact CA-O 3.3Å; Y99-G161 WeakPolarHBondContact CA-O 3.49Å; K158-G161 PolarHBondContact O-N 3.06Å; G161-L163 VanDerWaalsContact C-N 3.34Å; G161-L163 PolarHBondContact O-N 2.77Å; G161-K164 PolarHBondContact O-N 3.41Å; G161-G165 PolarHBondContact O-N 3.15Å
162A98.7Very high97.8Very high0 Ų027.3 Ų27.30%014%0.143CC..Hα-helixtrans-65-35.1173.800000113.3V53 A98 G102 K158 V159 F160 A166V53-A162 HydrophobicContact CG1-CB 3.84Å; V53-A162 HydrophobicContact CG2-CB 4.03Å; A98-A162 HydrophobicContact CB-CB 4.4Å; A98-A162 VanDerWaalsContact O-CA 3.25Å; A98-A162 WeakPolarHBondContact O-CA 3.37Å; A98-A162 WeakPolarHBondContact O-CB 3.32Å; G102-A162 WeakPolarHBondContact CA-O 3.47Å; K158-A162 PolarHBondContact O-N 2.8Å; V159-A162 PolarHBondContact O-N 2.98Å; F160-A162 VanDerWaalsContact C-N 3.34Å; F160-A162 PolarHBondContact O-N 3.06Å; A162-A166 WeakPolarHBondContact O-CB 3.32Å; A162-A166 PolarHBondContact O-N 3.45Å
163L98.6Very high97.8Very high4 Ų417.7 Ų17.72%0.02111%0.107CC..Hα-helixtrans-61.8-49.5172175.1137.1000111.2L146 V159 F160 G161 G165 A166 V167 I173 H175 F180L146-L163 HydrophobicContact CB-CD1 3.85Å; L146-L163 HydrophobicContact CD1-CB 4.4Å; L146-L163 HydrophobicContact CD1-CD1 4.18Å; L146-L163 HydrophobicContact CD2-CD1 3.7Å; L146-L163 HydrophobicContact CG-CD1 4.1Å; V159-L163 PolarHBondContact O-N 3.23Å; V159-L163 VanDerWaalsContact O-N 3.13Å; F160-L163 WeakPolarHBondContact O-CB 3.19Å; F160-L163 PolarHBondContact O-N 3.39Å; G161-L163 VanDerWaalsContact C-N 3.34Å; G161-L163 PolarHBondContact O-N 2.77Å; L163-G165 PolarHBondContact O-N 3.28Å; L163-A166 WeakPolarHBondContact O-CB 3.46Å; L163-A166 PolarHBondContact O-N 3.25Å; L163-A166 VanDerWaalsContact O-N 3.13Å; L163-V167 HydrophobicContact CD2-CG2 4.36Å; L163-V167 HydrophobicContact CG-CG2 4.48Å; L163-V167 WeakPolarHBondContact O-CG2 3.35Å; L163-V167 PolarHBondContact O-N 2.82Å; L163-I173 HydrophobicContact CD1-CG2 3.74Å; L163-I173 HydrophobicContact CG-CG2 4.32Å; L163-H175 HydrophobicContact CD1-CB 4.32Å; L163-H175 HydrophobicContact CD2-CB 3.85Å; L163-F180 HydrophobicContact CD2-CE1 3.98Å; L163-F180 HydrophobicContact CD2-CZ 3.62Å
164K98.6Very high97.9Very high0 Ų018.8 Ų18.80%012%0.115CC..Hα-helixtrans-63.2-42.1-179.4-176.658174157.10111.5Y99 D128 F160 G161 A166 V167 D168 F180 I199Y99-K164 HydrophobicContact CD2-CB 4.27Å; Y99-K164 HydrophobicContact CD2-CG 4.22Å; Y99-K164 HydrophobicContact CE2-CB 4.4Å; Y99-K164 HydrophobicContact CE2-CG 3.92Å; D128-K164 VanDerWaalsContact O-CE 3.3Å; D128-K164 WeakPolarHBondContact O-CE 3.45Å; D128-K164 PolarHBondContact O-NZ 2.9Å; F160-K164 PolarHBondContact O-N 3.44Å; G161-K164 PolarHBondContact O-N 3.41Å; K164-A166 VanDerWaalsContact C-N 3.28Å; K164-A166 PolarHBondContact O-N 3.31Å; K164-V167 PolarHBondContact O-N 3.05Å; K164-D168 WeakPolarHBondContact CD-OD1 3.4Å; K164-D168 WeakPolarHBondContact CE-OD1 3.27Å; K164-D168 WeakPolarHBondContact CE-OD2 3.26Å; K164-D168 IonicContact NZ-OD1 2.75Å; K164-D168 PolarHBondContact NZ-OD1 3.39Å; K164-D168 IonicContact NZ-OD2 3.77Å; K164-D168 WeakPolarHBondContact O-CB 3.43Å; K164-D168 PolarHBondContact O-N 3.37Å; K164-F180 HydrophobicContact CB-CE1 3.72Å; K164-F180 HydrophobicContact CB-CZ 4.04Å; K164-F180 HydrophobicContact CD-CZ 4.29Å; K164-F180 HydrophobicContact CG-CE1 4.48Å; K164-I199 HydrophobicContact CG-CD1 4.33Å
165G98.3Very high97.9Very high0 Ų017 Ų170%010%0.101CC..Hα-helixtrans-60.5-37.5174.100000112.9Y99 L103 G161 L163 G169Y99-G165 VanDerWaalsContact CD2-CA 3.47Å; Y99-G165 VanDerWaalsContact CE2-CA 3.49Å; L103-G165 WeakPolarHBondContact CA-O 3.3Å; L103-G165 PolarHBondContact N-O 2.85Å; G161-G165 PolarHBondContact O-N 3.15Å; L163-G165 PolarHBondContact O-N 3.28Å; G165-G169 PolarHBondContact O-N 2.92Å
166A98.5Very high97.9Very high0 Ų017.9 Ų17.90%011%0.11CC..Hα-helixtrans-70.4-36.9176.600000112.9L51 A106 A162 L163 K164 G169 L171 I173L51-A166 HydrophobicContact CD2-CB 3.79Å; A106-A166 HydrophobicContact CB-CB 4.49Å; A106-A166 WeakPolarHBondContact CB-O 3.22Å; A162-A166 WeakPolarHBondContact O-CB 3.32Å; A162-A166 PolarHBondContact O-N 3.45Å; L163-A166 WeakPolarHBondContact O-CB 3.46Å; L163-A166 PolarHBondContact O-N 3.25Å; L163-A166 VanDerWaalsContact O-N 3.13Å; K164-A166 VanDerWaalsContact C-N 3.28Å; K164-A166 PolarHBondContact O-N 3.31Å; A166-G169 PolarHBondContact O-N 3.34Å; A166-L171 HydrophobicContact CB-CD1 4.26Å; A166-L171 WeakPolarHBondContact O-CB 3.29Å; A166-L171 PolarHBondContact O-N 2.84Å; A166-I173 HydrophobicContact CB-CD1 3.83Å
167V98.4Very high97.9Very high0 Ų017.7 Ų17.70%010%0.101CC..Hα-helixtrans-64.8-53.4174.3166.20000110.8F130 L163 K164 G169 G170 I173F130-V167 HydrophobicContact CD1-CG1 4.12Å; F130-V167 WeakPolarHBondContact O-CG1 3.42Å; L163-V167 HydrophobicContact CD2-CG2 4.36Å; L163-V167 HydrophobicContact CG-CG2 4.48Å; L163-V167 WeakPolarHBondContact O-CG2 3.35Å; L163-V167 PolarHBondContact O-N 2.82Å; K164-V167 PolarHBondContact O-N 3.05Å; V167-G169 PolarHBondContact O-N 3.31Å; V167-G169 VanDerWaalsContact O-N 3.12Å; V167-G170 PolarHBondContact O-N 3.02Å; V167-I173 HydrophobicContact CG2-CB 3.82Å; V167-I173 HydrophobicContact CG2-CD1 4.32Å; V167-I173 HydrophobicContact CG2-CG1 4.18Å
168D98.3Very high97.8Very high0 Ų021.6 Ų21.60%012%0.117CC..Hα-helixtrans-64.3-19.5178.1-65.9-4.1000112.2Y99 G121 Q122 K164 G170Y99-D168 HydrophobicContact CE2-CB 4.41Å; Y99-D168 VanDerWaalsContact CE2-OD2 3.23Å; Y99-D168 WeakPolarHBondContact CE2-OD2 3.48Å; Y99-D168 VanDerWaalsContact OH-CB 3.32Å; Y99-D168 WeakPolarHBondContact OH-CB 3.31Å; Y99-D168 PolarHBondContact OH-OD2 3.15Å; G121-D168 CarbonylContact C-O 3.46Å; G121-D168 WeakPolarHBondContact CA-O 3.22Å; Q122-D168 HydrophobicContact CB-CB 4.26Å; Q122-D168 PolarHBondContact N-O 2.97Å; K164-D168 WeakPolarHBondContact CD-OD1 3.4Å; K164-D168 WeakPolarHBondContact CE-OD1 3.27Å; K164-D168 WeakPolarHBondContact CE-OD2 3.26Å; K164-D168 IonicContact NZ-OD1 2.75Å; K164-D168 PolarHBondContact NZ-OD1 3.39Å; K164-D168 IonicContact NZ-OD2 3.77Å; K164-D168 WeakPolarHBondContact O-CB 3.43Å; K164-D168 PolarHBondContact O-N 3.37Å; D168-G170 VanDerWaalsContact C-N 3.32Å
169G97.4Very high97.8Very high0 Ų023.6 Ų23.60%012%0.122CC..THydrogen-bonded Turntrans-81.1-4.7173.500000115.2R107 L110 G165 A166 V167R107-G169 WeakPolarHBondContact CD-O 3.47Å; L110-G169 WeakPolarHBondContact CD1-O 3.49Å; G165-G169 PolarHBondContact O-N 2.92Å; A166-G169 PolarHBondContact O-N 3.34Å; V167-G169 PolarHBondContact O-N 3.31Å; V167-G169 VanDerWaalsContact O-N 3.12Å
170G96.9Very high97.7Very high0 Ų023.6 Ų23.60%012%0.122CC..THydrogen-bonded Turntrans111.66.4174.800000115.7V167 D168V167-G170 PolarHBondContact O-N 3.02Å; D168-G170 VanDerWaalsContact C-N 3.32Å
171L98Very high97.6Very high0 Ų023.1 Ų23.10%012%0.121CC..  trans-89.3138.3177.9-55.7-171.7000112I64 A106 L109 L110 F142 A166 I173I64-L171 HydrophobicContact CD1-CD1 4.21Å; A106-L171 HydrophobicContact CB-CD1 3.99Å; A106-L171 HydrophobicContact CB-CD2 4.33Å; A106-L171 HydrophobicContact CB-CG 3.7Å; L109-L171 HydrophobicContact CD2-CD1 4.24Å; L109-L171 HydrophobicContact CD2-CD2 3.75Å; L110-L171 HydrophobicContact CD2-CD2 4.08Å; L110-L171 HydrophobicContact CG-CD2 4.14Å; F142-L171 HydrophobicContact CB-CD2 4.03Å; F142-L171 HydrophobicContact CD1-CD2 4.1Å; F142-L171 HydrophobicContact CG-CD2 4.38Å; A166-L171 HydrophobicContact CB-CD1 4.26Å; A166-L171 WeakPolarHBondContact O-CB 3.29Å; A166-L171 PolarHBondContact O-N 2.84Å; L171-I173 HydrophobicContact CB-CD1 4.21Å; L171-I173 HydrophobicContact CB-CG1 3.99Å; L171-I173 PolarHBondContact O-N 3.34Å
172A97.9Very high97.5Very high19 Ų1924.2 Ų24.216%0.15713%0.132CC..BIsolated β-bridgetrans-81.197.8171.800000109.8A141 F142 T143 C144A141-A172 HydrophobicContact CB-CB 4.01Å; F142-A172 PolarHBondContact O-N 2.89Å; T143-A172 WeakPolarHBondContact CA-O 3.37Å; C144-A172 PolarHBondContact N-O 2.98Å
173I98.2Very high97.4Very high4 Ų426.1 Ų26.12%0.02114%0.14CC..  trans-120.4114.6178-50-174.1000108.7L51 C144 L163 A166 V167 L171 H175L51-I173 HydrophobicContact CD2-CD1 3.59Å; C144-I173 VanDerWaalsContact SG-CG1 3.59Å; L163-I173 HydrophobicContact CD1-CG2 3.74Å; L163-I173 HydrophobicContact CG-CG2 4.32Å; A166-I173 HydrophobicContact CB-CD1 3.83Å; V167-I173 HydrophobicContact CG2-CB 3.82Å; V167-I173 HydrophobicContact CG2-CD1 4.32Å; V167-I173 HydrophobicContact CG2-CG1 4.18Å; L171-I173 HydrophobicContact CB-CD1 4.21Å; L171-I173 HydrophobicContact CB-CG1 3.99Å; L171-I173 PolarHBondContact O-N 3.34Å; I173-H175 PolarHBondContact O-N 3.3Å; I173-H175 PolarHBondContact O-ND1 3.12Å
174P97.8Very high97.2Very high86 Ų8629 Ų2956%0.55816%0.155SC*.  trans-67.6125.117927.1-32.8000110.2C144 Y145C144-P174 WeakPolarHBondContact O-CD 3.44Å; Y145-P174 HydrophobicContact CD1-CG 3.78Å; Y145-P174 HydrophobicContact CE1-CG 3.89Å
175H97.3Very high96.9Very high39 Ų3933.7 Ų33.718%0.18118%0.183CC..  trans-152.3178.7-17867.5-75.6000111.6F130 N131 L163 I173 F180F130-H175 PolarHBondContact O-CE1 3.48Å; N131-H175 PolarHBondContact OD1-CE1 3.39Å; N131-H175 PolarHBondContact OD1-ND1 3.33Å; L163-H175 HydrophobicContact CD1-CB 4.32Å; L163-H175 HydrophobicContact CD2-CB 3.85Å; I173-H175 PolarHBondContact O-N 3.3Å; I173-H175 PolarHBondContact O-ND1 3.12Å; H175-F180 AromaticContact CD2-CE2 3.61Å; H175-F180 AromaticContact CD2-CZ 3.65Å
176S96.3Very high96.7Very high64 Ų6442 Ų4245%0.44822%0.222SC..  trans-141.5152.2175.1170.80000108.7K178S176-K178 PolarHBondContact O-N 2.91Å
177L95.1Very high96.5Very high26 Ų2644.8 Ų44.814%0.13624%0.242CC..G310 helixtrans-65.9-17.4-176-59.2169.9000115E129 R179 F180 F190E129-L177 HydrophobicContact CB-CD1 3.99Å; E129-L177 HydrophobicContact CB-CD2 3.65Å; E129-L177 HydrophobicContact CB-CG 4.07Å; E129-L177 HydrophobicContact CG-CD2 4.11Å; E129-L177 HydrophobicContact CG-CG 4.36Å; L177-R179 PolarHBondContact O-N 2.93Å; L177-F180 HydrophobicContact CB-CD2 4.49Å; L177-F180 HydrophobicContact CD2-CD2 4.01Å; L177-F180 HydrophobicContact CD2-CE2 4.11Å; L177-F180 PolarHBondContact O-N 3.25Å; L177-F180 VanDerWaalsContact O-N 3.09Å; L177-F190 HydrophobicContact CB-CB 4.36Å; L177-F190 HydrophobicContact CB-CD1 4.31Å; L177-F190 HydrophobicContact CB-CD2 4.17Å; L177-F190 HydrophobicContact CB-CG 4.01Å; L177-F190 HydrophobicContact CD1-CB 4.22Å; L177-F190 HydrophobicContact CD1-CD1 3.71Å; L177-F190 HydrophobicContact CD1-CE1 4.33Å; L177-F190 HydrophobicContact CD1-CG 4.04Å; L177-F190 HydrophobicContact CD2-CD1 4.17Å; L177-F190 HydrophobicContact CD2-CE1 3.96Å; L177-F190 HydrophobicContact CD2-CZ 4.28Å; L177-F190 HydrophobicContact CG-CD1 4.29Å; L177-F190 HydrophobicContact CG-CG 4.47Å
178K96.7Very high96.3Very high116 Ų11652.2 Ų52.250%0.50427%0.274SS..G310 helixtrans-56.9-19.1-170.8-63.9-174.8177.4179.10116.1T155 S176 Y183T155-K178 PolarHBondContact OG1-O 3.43Å; T155-K178 VanDerWaalsContact OG1-O 3.07Å; S176-K178 PolarHBondContact O-N 2.91Å; K178-Y183 HydrophobicContact CB-CD1 4.36Å; K178-Y183 HydrophobicContact CB-CD2 4.48Å; K178-Y183 HydrophobicContact CB-CE1 4.2Å; K178-Y183 HydrophobicContact CB-CE2 4.31Å; K178-Y183 HydrophobicContact CB-CG 4.49Å; K178-Y183 HydrophobicContact CG-CD2 4.36Å; K178-Y183 HydrophobicContact CG-CE1 4.25Å; K178-Y183 HydrophobicContact CG-CE2 3.79Å; K178-Y183 WeakPolarHBondContact O-CD1 3.35Å
179R96.8Very high96.1Very high115 Ų11558.9 Ų58.943%0.43431%0.305SS..G310 helixtrans-108.5-1.9-175.2-61.7-58.3-179.3-162.1-0.3114.1T155 G156 F160 L177T155-R179 WeakPolarHBondContact CA-O 3.39Å; T155-R179 PolarHBondContact OG1-NH1 2.93Å; G156-R179 PolarHBondContact N-O 3.45Å; F160-R179 HydrophobicContact CD1-CB 4.18Å; F160-R179 HydrophobicContact CD2-CB 3.75Å; F160-R179 HydrophobicContact CE1-CB 4.01Å; F160-R179 HydrophobicContact CE1-CG 4.42Å; F160-R179 HydrophobicContact CE2-CB 3.56Å; F160-R179 HydrophobicContact CE2-CG 4.09Å; F160-R179 HydrophobicContact CG-CB 4.06Å; F160-R179 HydrophobicContact CZ-CB 3.7Å; F160-R179 HydrophobicContact CZ-CG 3.91Å; L177-R179 PolarHBondContact O-N 2.93Å
180F97.8Very high96.1Very high2 Ų261 Ų611%0.00932%0.315CS..SBendtrans-80.6153.1174.1-63.5-55.5000112T155 F160 L163 K164 H175 L177 Y183 F190 H195T155-F180 WeakPolarHBondContact CG2-O 3.47Å; F160-F180 HydrophobicContact CB-CD1 3.85Å; F160-F180 HydrophobicContact CB-CE1 3.81Å; F160-F180 WeakPolarHBondContact O-CE1 3.47Å; L163-F180 HydrophobicContact CD2-CE1 3.98Å; L163-F180 HydrophobicContact CD2-CZ 3.62Å; K164-F180 HydrophobicContact CB-CE1 3.72Å; K164-F180 HydrophobicContact CB-CZ 4.04Å; K164-F180 HydrophobicContact CD-CZ 4.29Å; K164-F180 HydrophobicContact CG-CE1 4.48Å; H175-F180 AromaticContact CD2-CE2 3.61Å; H175-F180 AromaticContact CD2-CZ 3.65Å; L177-F180 HydrophobicContact CB-CD2 4.49Å; L177-F180 HydrophobicContact CD2-CD2 4.01Å; L177-F180 HydrophobicContact CD2-CE2 4.11Å; L177-F180 PolarHBondContact O-N 3.25Å; L177-F180 VanDerWaalsContact O-N 3.09Å; F180-Y183 PolarHBondContact O-N 2.9Å; F180-F190 HydrophobicContact CB-CE2 3.88Å; F180-F190 HydrophobicContact CB-CZ 4.41Å; F180-H195 AromaticContact CD1-CE1 3.64Å; F180-H195 AromaticContact CD1-NE2 3.6Å; F180-H195 AromaticContact CD2-CE1 3.93Å; F180-H195 AromaticContact CG-CE1 3.52Å; F180-H195 AromaticContact CG-NE2 3.78Å
181P96.7Very high96Very high10 Ų1064.4 Ų64.47%0.06533%0.333CS..THydrogen-bonded Turntrans-53.4139.4164-15.526.1000110.1Y95 H195 H198Y95-P181 HydrophobicContact CD2-CG 4.21Å; Y95-P181 HydrophobicContact CE1-CG 4.31Å; Y95-P181 HydrophobicContact CE2-CG 3.63Å; Y95-P181 VanDerWaalsContact OH-CD 3.29Å; Y95-P181 WeakPolarHBondContact OH-CD 3.35Å; P181-H195 WeakPolarHBondContact O-CA 3.46Å; P181-H195 VanDerWaalsContact O-CB 3.28Å; P181-H195 WeakPolarHBondContact O-CB 3.38Å; P181-H198 HydrophobicContact CB-CB 4.19Å; P181-H198 HydrophobicContact CG-CB 4.08Å
182G94.9Very high96Very high23 Ų2365.6 Ų65.624%0.23734%0.342CS..THydrogen-bonded Turntrans96.1-8-176.900000114.8N191G182-N191 PolarHBondContact O-N 3.14Å
183Y96.8Very high95.9Very high41 Ų4171.1 Ų71.116%0.16137%0.365CS..BIsolated β-bridgetrans-82.1122.6167.4-175.7-95.8000110.7K178 F180 T185 F190K178-Y183 HydrophobicContact CB-CD1 4.36Å; K178-Y183 HydrophobicContact CB-CD2 4.48Å; K178-Y183 HydrophobicContact CB-CE1 4.2Å; K178-Y183 HydrophobicContact CB-CE2 4.31Å; K178-Y183 HydrophobicContact CB-CG 4.49Å; K178-Y183 HydrophobicContact CG-CD2 4.36Å; K178-Y183 HydrophobicContact CG-CE1 4.25Å; K178-Y183 HydrophobicContact CG-CE2 3.79Å; K178-Y183 WeakPolarHBondContact O-CD1 3.35Å; F180-Y183 PolarHBondContact O-N 2.9Å; Y183-T185 HydrophobicContact CD1-CG2 4.37Å; Y183-T185 HydrophobicContact CE1-CG2 4.22Å; Y183-F190 HydrophobicContact CD2-CB 4.24Å
184D95.1Very high95.8Very high65 Ų6573.4 Ų73.435%0.34838%0.379SS..  trans-94.5129.5172.7174.630.7000110.9E186 S187 K188 E189D184-E186 PolarHBondContact OD1-N 2.96Å; D184-E186 VanDerWaalsContact OD1-N 3.1Å; D184-S187 WeakPolarHBondContact CB-OG 3.49Å; D184-S187 VanDerWaalsContact CG-OG 3.31Å; D184-S187 VanDerWaalsContact OD2-CB 3.24Å; D184-S187 WeakPolarHBondContact OD2-CB 3.25Å; D184-S187 PolarHBondContact OD2-N 3Å; D184-S187 PolarHBondContact OD2-OG 3.48Å; D184-K188 WeakPolarHBondContact O-CA 3.4Å; D184-K188 PolarHBondContact O-N 3.09Å; D184-E189 PolarHBondContact N-O 3.26Å
185T91.9Very high95.8Very high97 Ų9769.3 Ų69.360%0.59535%0.352SS*.THydrogen-bonded Turntrans-76.3-24.4-178.747.20000113.5Y183Y183-T185 HydrophobicContact CD1-CG2 4.37Å; Y183-T185 HydrophobicContact CE1-CG2 4.22Å
186E93.1Very high95.8Very high175 Ų17572.4 Ų72.482%0.81836%0.362SS*.THydrogen-bonded Turntrans-81.9-57.2-177.3-64.4-177.3-175.400110.9D184 K188D184-E186 PolarHBondContact OD1-N 2.96Å; D184-E186 VanDerWaalsContact OD1-N 3.1Å; E186-K188 VanDerWaalsContact C-N 3.29Å; E186-K188 PolarHBondContact O-N 3.11Å
187S94.5Very high95.9Very high58 Ų5874.7 Ų74.741%0.40636%0.364SS..THydrogen-bonded Turntrans-71-22.8175.260.30000113.5D184 E189D184-S187 WeakPolarHBondContact CB-OG 3.49Å; D184-S187 VanDerWaalsContact CG-OG 3.31Å; D184-S187 VanDerWaalsContact OD2-CB 3.24Å; D184-S187 WeakPolarHBondContact OD2-CB 3.25Å; D184-S187 PolarHBondContact OD2-N 3Å; D184-S187 PolarHBondContact OD2-OG 3.48Å; S187-E189 PolarHBondContact O-N 2.95Å; S187-E189 PolarHBondContact OG-N 3.12Å
188K94.2Very high96Very high156 Ų15675.7 Ų75.768%0.67837%0.368SS*.  trans62.621.5-171.1-53.6171.8-175.9164.50113.4D184 E186D184-K188 WeakPolarHBondContact O-CA 3.4Å; D184-K188 PolarHBondContact O-N 3.09Å; E186-K188 VanDerWaalsContact C-N 3.29Å; E186-K188 PolarHBondContact O-N 3.11Å
189E94.9Very high96.1Very high141 Ų14170.2 Ų70.266%0.65934%0.344SS*.  trans-98154.8178.1-64.8-179.7176.400111.3D184 S187D184-E189 PolarHBondContact N-O 3.26Å; S187-E189 PolarHBondContact O-N 2.95Å; S187-E189 PolarHBondContact OG-N 3.12Å
190F96.1Very high96.1Very high44 Ų4465.1 Ų65.119%0.19333%0.326CS..BIsolated β-bridgetrans-116.9122.8178.2177.1-109.2000110.3G127 L177 F180 Y183 A192 H195G127-F190 WeakPolarHBondContact O-CE1 3.38Å; G127-F190 WeakPolarHBondContact O-CZ 3.3Å; L177-F190 HydrophobicContact CB-CB 4.36Å; L177-F190 HydrophobicContact CB-CD1 4.31Å; L177-F190 HydrophobicContact CB-CD2 4.17Å; L177-F190 HydrophobicContact CB-CG 4.01Å; L177-F190 HydrophobicContact CD1-CB 4.22Å; L177-F190 HydrophobicContact CD1-CD1 3.71Å; L177-F190 HydrophobicContact CD1-CE1 4.33Å; L177-F190 HydrophobicContact CD1-CG 4.04Å; L177-F190 HydrophobicContact CD2-CD1 4.17Å; L177-F190 HydrophobicContact CD2-CE1 3.96Å; L177-F190 HydrophobicContact CD2-CZ 4.28Å; L177-F190 HydrophobicContact CG-CD1 4.29Å; L177-F190 HydrophobicContact CG-CG 4.47Å; F180-F190 HydrophobicContact CB-CE2 3.88Å; F180-F190 HydrophobicContact CB-CZ 4.41Å; Y183-F190 HydrophobicContact CD2-CB 4.24Å; F190-A192 HydrophobicContact CD1-CB 4.45Å; F190-A192 HydrophobicContact CE1-CB 3.89Å; F190-H195 HydrophobicContact CE2-CB 4.1Å; F190-H195 HydrophobicContact CZ-CB 3.65Å; F190-H195 AromaticContact CZ-CG 3.92Å; F190-H195 AromaticContact CZ-ND1 3.6Å
191N96.6Very high96.1Very high72 Ų7265.1 Ų65.139%0.38533%0.326SS..  trans-98.3103.5173.6-173-41.2000110.5G182 E193 V194 H195G182-N191 PolarHBondContact O-N 3.14Å; N191-E193 VanDerWaalsContact C-N 3.29Å; N191-E193 PolarHBondContact O-N 2.84Å; N191-E193 WeakPolarHBondContact OD1-CA 3.44Å; N191-E193 WeakPolarHBondContact OD1-CB 3.5Å; N191-E193 PolarHBondContact OD1-N 2.98Å; N191-V194 HydrophobicContact CB-CB 4.34Å; N191-V194 HydrophobicContact CB-CG2 4.1Å; N191-V194 PolarHBondContact O-N 2.79Å; N191-V194 PolarHBondContact OD1-N 3.06Å; N191-H195 PolarHBondContact O-N 2.91Å
192A96.6Very high96.1Very high24 Ų2467.1 Ų67.120%0.19834%0.335CS..Hα-helixtrans-63.1-31.9179.100000113.1D128 F190 H195 R196D128-A192 HydrophobicContact CB-CB 4.03Å; F190-A192 HydrophobicContact CD1-CB 4.45Å; F190-A192 HydrophobicContact CE1-CB 3.89Å; A192-H195 WeakPolarHBondContact O-CB 3.29Å; A192-H195 PolarHBondContact O-N 3.08Å; A192-R196 WeakPolarHBondContact O-CB 3.38Å; A192-R196 PolarHBondContact O-N 3.31Å
193E96.4Very high96.2Very high135 Ų13568.9 Ų68.963%0.63134%0.339SS*.Hα-helixtrans-66.4-41.5179-56.8-173.4162.400111.6N191 H195 R196 K197N191-E193 VanDerWaalsContact C-N 3.29Å; N191-E193 PolarHBondContact O-N 2.84Å; N191-E193 WeakPolarHBondContact OD1-CA 3.44Å; N191-E193 WeakPolarHBondContact OD1-CB 3.5Å; N191-E193 PolarHBondContact OD1-N 2.98Å; E193-H195 VanDerWaalsContact C-N 3.29Å; E193-H195 PolarHBondContact O-N 2.81Å; E193-R196 PolarHBondContact O-N 2.91Å; E193-K197 WeakPolarHBondContact O-CG 3.45Å; E193-K197 PolarHBondContact O-N 3.18Å
194V96.6Very high96.2Very high52 Ų5268.3 Ų68.332%0.31534%0.34SS..Hα-helixtrans-62.7-40.4174.9174.90000110.4N191 K197 H198N191-V194 HydrophobicContact CB-CB 4.34Å; N191-V194 HydrophobicContact CB-CG2 4.1Å; N191-V194 PolarHBondContact O-N 2.79Å; N191-V194 PolarHBondContact OD1-N 3.06Å; V194-K197 PolarHBondContact O-N 3.48Å; V194-H198 PolarHBondContact O-N 3.48Å; V194-H198 PolarHBondContact O-ND1 2.77Å
195H97.9Very high96.3Very high0 Ų065.4 Ų65.40%033%0.325CS..Hα-helixtrans-63-46.9175.2-172.4-160.3000111.6Y95 G127 F180 P181 F190 N191 A192 E193 K197 H198 I199Y95-H195 AromaticContact CZ-NE2 3.94Å; Y95-H195 PolarHBondContact OH-NE2 3.28Å; G127-H195 PolarHBondContact O-ND1 3.39Å; F180-H195 AromaticContact CD1-CE1 3.64Å; F180-H195 AromaticContact CD1-NE2 3.6Å; F180-H195 AromaticContact CD2-CE1 3.93Å; F180-H195 AromaticContact CG-CE1 3.52Å; F180-H195 AromaticContact CG-NE2 3.78Å; P181-H195 WeakPolarHBondContact O-CA 3.46Å; P181-H195 VanDerWaalsContact O-CB 3.28Å; P181-H195 WeakPolarHBondContact O-CB 3.38Å; F190-H195 HydrophobicContact CE2-CB 4.1Å; F190-H195 HydrophobicContact CZ-CB 3.65Å; F190-H195 AromaticContact CZ-CG 3.92Å; F190-H195 AromaticContact CZ-ND1 3.6Å; N191-H195 PolarHBondContact O-N 2.91Å; A192-H195 WeakPolarHBondContact O-CB 3.29Å; A192-H195 PolarHBondContact O-N 3.08Å; E193-H195 VanDerWaalsContact C-N 3.29Å; E193-H195 PolarHBondContact O-N 2.81Å; H195-K197 VanDerWaalsContact C-N 3.33Å; H195-K197 PolarHBondContact O-N 3.19Å; H195-H198 WeakPolarHBondContact O-CB 3.39Å; H195-H198 PolarHBondContact O-N 2.75Å; H195-I199 WeakPolarHBondContact O-CG1 3.36Å; H195-I199 PolarHBondContact O-N 3.03Å
196R97.4Very high96.5Very high104 Ų10465.3 Ų65.339%0.39232%0.321SS..Hα-helixtrans-57.8-43176.6-173.9178.9176.8-117.5-1.2112.1V125 T126 A192 E193 H198 I199 M200V125-R196 WeakPolarHBondContact O-CD 3.27Å; V125-R196 PolarHBondContact O-NE 3.48Å; T126-R196 WeakPolarHBondContact O-CB 3.42Å; A192-R196 WeakPolarHBondContact O-CB 3.38Å; A192-R196 PolarHBondContact O-N 3.31Å; E193-R196 PolarHBondContact O-N 2.91Å; R196-H198 VanDerWaalsContact C-N 3.28Å; R196-H198 PolarHBondContact O-N 2.85Å; R196-I199 PolarHBondContact O-N 3.13Å; R196-I199 VanDerWaalsContact O-N 3.13Å; R196-M200 PolarHBondContact O-N 3.29Å
197K97.6Very high96.7Very high112 Ų11262.1 Ų62.149%0.48730%0.302SS..Hα-helixtrans-56.5-40.8174-75.9178.9-177.4-176.70112.1E193 V194 H195 G201 M202E193-K197 WeakPolarHBondContact O-CG 3.45Å; E193-K197 PolarHBondContact O-N 3.18Å; V194-K197 PolarHBondContact O-N 3.48Å; H195-K197 VanDerWaalsContact C-N 3.33Å; H195-K197 PolarHBondContact O-N 3.19Å; K197-G201 PolarHBondContact O-N 2.89Å; K197-G201 VanDerWaalsContact O-N 3.11Å; K197-M202 HydrophobicContact CB-CB 4.04Å; K197-M202 HydrophobicContact CB-CG 4.4Å; K197-M202 HydrophobicContact CG-CB 4.28Å; K197-M202 HydrophobicContact CG-CG 4.4Å; K197-M202 WeakPolarHBondContact O-CB 3.36Å; K197-M202 PolarHBondContact O-N 2.86Å
198H97.9Very high96.9Very high48 Ų4859.4 Ų59.422%0.22228%0.283CS..Hα-helixtrans-70.7-36.7175.9-74.576.7000113.1Y95 P181 V194 H195 R196 M200 G201 N203Y95-H198 HydrophobicContact CD1-CB 3.91Å; Y95-H198 HydrophobicContact CE1-CB 4.23Å; Y95-H198 HydrophobicContact CG-CB 4.37Å; P181-H198 HydrophobicContact CB-CB 4.19Å; P181-H198 HydrophobicContact CG-CB 4.08Å; V194-H198 PolarHBondContact O-N 3.48Å; V194-H198 PolarHBondContact O-ND1 2.77Å; H195-H198 WeakPolarHBondContact O-CB 3.39Å; H195-H198 PolarHBondContact O-N 2.75Å; R196-H198 VanDerWaalsContact C-N 3.28Å; R196-H198 PolarHBondContact O-N 2.85Å; H198-M200 VanDerWaalsContact C-N 3.34Å; H198-G201 PolarHBondContact O-N 3.03Å; H198-N203 PolarHBondContact CD2-ND2 2.89Å; H198-N203 VanDerWaalsContact CD2-ND2 3.31Å
199I97.9Very high97Very high0 Ų053.9 Ų53.90%026%0.264CS..Hα-helixtrans-64.5-41.1176-65.3166.1000110.6Y95 A96 Y99 V125 K164 H195 R196 G201Y95-I199 HydrophobicContact CE1-CG1 3.99Å; A96-I199 WeakPolarHBondContact CA-O 3.47Å; A96-I199 WeakPolarHBondContact CB-O 3.21Å; Y99-I199 HydrophobicContact CD1-CG2 3.58Å; Y99-I199 HydrophobicContact CD2-CB 4.48Å; Y99-I199 HydrophobicContact CD2-CD1 4.15Å; Y99-I199 HydrophobicContact CD2-CG1 3.97Å; Y99-I199 HydrophobicContact CD2-CG2 3.72Å; Y99-I199 HydrophobicContact CE1-CG2 3.76Å; Y99-I199 HydrophobicContact CE2-CD1 4.01Å; Y99-I199 HydrophobicContact CE2-CG1 4.3Å; Y99-I199 HydrophobicContact CE2-CG2 3.86Å; Y99-I199 HydrophobicContact CG-CG1 4.46Å; Y99-I199 HydrophobicContact CG-CG2 3.57Å; V125-I199 HydrophobicContact CG1-CB 4.3Å; V125-I199 HydrophobicContact CG1-CD1 3.84Å; V125-I199 HydrophobicContact CG1-CG2 3.78Å; K164-I199 HydrophobicContact CG-CD1 4.33Å; H195-I199 WeakPolarHBondContact O-CG1 3.36Å; H195-I199 PolarHBondContact O-N 3.03Å; R196-I199 PolarHBondContact O-N 3.13Å; R196-I199 VanDerWaalsContact O-N 3.13Å; I199-G201 VanDerWaalsContact C-N 3.27Å; I199-G201 PolarHBondContact O-N 3.42Å
200M97.4Very high97.1Very high9 Ų953.3 Ų53.34%0.04426%0.257CS..THydrogen-bonded Turntrans-82.3-0.9178.1-63.2-55.1-177.900114.1V125 R196 H198 M202 E237 Y240 K241V125-M200 HydrophobicContact CB-CE 3.67Å; V125-M200 HydrophobicContact CG1-CE 4.17Å; V125-M200 HydrophobicContact CG2-CE 4.04Å; R196-M200 PolarHBondContact O-N 3.29Å; H198-M200 VanDerWaalsContact C-N 3.34Å; M200-M202 VanDerWaalsContact C-N 3.27Å; M200-M202 HydrophobicContact CB-CG 4.17Å; M200-M202 PolarHBondContact O-N 2.99Å; M200-E237 HydrophobicContact CB-CG 4.12Å; M200-E237 HydrophobicContact CG-CG 4.33Å; M200-Y240 WeakPolarHBondContact O-CD2 3.36Å; M200-K241 HydrophobicContact CE-CG 4.22Å; M200-K241 HydrophobicContact SD-CG 4.18Å
201G96.8Very high97.1Very high1 Ų151.9 Ų51.91%0.0125%0.251CS..THydrogen-bonded Turntrans7117.8179.100000114.8K197 H198 I199 N203 V204 A205K197-G201 PolarHBondContact O-N 2.89Å; K197-G201 VanDerWaalsContact O-N 3.11Å; H198-G201 PolarHBondContact O-N 3.03Å; I199-G201 VanDerWaalsContact C-N 3.27Å; I199-G201 PolarHBondContact O-N 3.42Å; G201-N203 VanDerWaalsContact C-N 3.27Å; G201-N203 PolarHBondContact O-N 3.19Å; G201-V204 WeakPolarHBondContact O-CB 3.36Å; G201-V204 PolarHBondContact O-N 2.73Å; G201-A205 PolarHBondContact O-N 3.31Å; G201-A205 VanDerWaalsContact O-N 3.16Å
202M97.1Very high97Very high52 Ų5252.8 Ų52.826%0.25625%0.254SS..Hα-helixtrans-59.5-38.2-179.7-64.2-57.7-71.100111.8K197 M200 V204 A205 D206 E237K197-M202 HydrophobicContact CB-CB 4.04Å; K197-M202 HydrophobicContact CB-CG 4.4Å; K197-M202 HydrophobicContact CG-CB 4.28Å; K197-M202 HydrophobicContact CG-CG 4.4Å; K197-M202 WeakPolarHBondContact O-CB 3.36Å; K197-M202 PolarHBondContact O-N 2.86Å; M200-M202 VanDerWaalsContact C-N 3.27Å; M200-M202 HydrophobicContact CB-CG 4.17Å; M200-M202 PolarHBondContact O-N 2.99Å; M202-V204 PolarHBondContact O-N 3Å; M202-V204 VanDerWaalsContact O-N 3.15Å; M202-A205 CarbonylContact O-C 3.55Å; M202-A205 WeakPolarHBondContact O-CA 3.29Å; M202-A205 WeakPolarHBondContact O-CB 3.48Å; M202-A205 PolarHBondContact O-N 2.88Å; M202-D206 PolarHBondContact O-N 2.89Å; M202-E237 HydrophobicContact SD-CB 3.74Å; M202-E237 HydrophobicContact SD-CG 4.27Å
203N96.5Very high97Very high61 Ų6159.5 Ų59.533%0.32628%0.281SS..Hα-helixtrans-60.3-27.6175.266.7-34.9000113.7H198 G201 Y207H198-N203 PolarHBondContact CD2-ND2 2.89Å; H198-N203 VanDerWaalsContact CD2-ND2 3.31Å; G201-N203 VanDerWaalsContact C-N 3.27Å; G201-N203 PolarHBondContact O-N 3.19Å; N203-Y207 PolarHBondContact O-N 3.04Å
204V96.6Very high97Very high29 Ų2959.3 Ų59.318%0.17628%0.281CS..Hα-helixtrans-77.9-40173.3-178.30000110G201 M202 Y207 M208 F223G201-V204 WeakPolarHBondContact O-CB 3.36Å; G201-V204 PolarHBondContact O-N 2.73Å; M202-V204 PolarHBondContact O-N 3Å; M202-V204 VanDerWaalsContact O-N 3.15Å; V204-Y207 PolarHBondContact O-N 3.07Å; V204-M208 HydrophobicContact CG1-SD 4.43Å; V204-M208 VanDerWaalsContact O-CG 3.28Å; V204-M208 WeakPolarHBondContact O-CG 3.5Å; V204-M208 PolarHBondContact O-N 2.87Å; V204-F223 HydrophobicContact CG1-CE1 3.97Å; V204-F223 HydrophobicContact CG1-CZ 4.35Å
205A97.3Very high96.9Very high4 Ų460.5 Ų60.53%0.03329%0.285CS..Hα-helixtrans-61.5-46.517400000111.6G201 M202 Y207 M208 S209 P233 V236G201-A205 PolarHBondContact O-N 3.31Å; G201-A205 VanDerWaalsContact O-N 3.16Å; M202-A205 CarbonylContact O-C 3.55Å; M202-A205 WeakPolarHBondContact O-CA 3.29Å; M202-A205 WeakPolarHBondContact O-CB 3.48Å; M202-A205 PolarHBondContact O-N 2.88Å; A205-Y207 VanDerWaalsContact C-N 3.27Å; A205-Y207 PolarHBondContact O-N 2.77Å; A205-M208 WeakPolarHBondContact O-CA 3.4Å; A205-M208 WeakPolarHBondContact O-CB 3.48Å; A205-M208 PolarHBondContact O-N 2.89Å; A205-S209 PolarHBondContact O-N 2.58Å; A205-S209 PolarHBondContact O-OG 2.75Å; A205-P233 HydrophobicContact CB-CB 4.14Å; A205-P233 WeakPolarHBondContact CB-O 3.24Å; A205-V236 HydrophobicContact CB-CB 4.19Å; A205-V236 HydrophobicContact CB-CG2 4.18Å
206D97.5Very high96.8Very high94 Ų9466 Ų6650%0.50331%0.31SS..Hα-helixtrans-56.4-43.1175.7-60.3-23.2000110.8M202 S209 Y210M202-D206 PolarHBondContact O-N 2.89Å; D206-S209 PolarHBondContact O-N 2.73Å; D206-Y210 WeakPolarHBondContact O-CB 3.4Å; D206-Y210 PolarHBondContact O-N 2.86Å
207Y97.8Very high96.7Very high109 Ų10966.7 Ų66.743%0.42732%0.322SS..Hα-helixtrans-69.7-32.1176.7-175.3-132.5000113.1N203 V204 A205 Y210 L211 Q222 F223N203-Y207 PolarHBondContact O-N 3.04Å; V204-Y207 PolarHBondContact O-N 3.07Å; A205-Y207 VanDerWaalsContact C-N 3.27Å; A205-Y207 PolarHBondContact O-N 2.77Å; Y207-Y210 HydrophobicContact CD2-CD1 4.15Å; Y207-Y210 HydrophobicContact CE2-CD1 4.27Å; Y207-L211 HydrophobicContact CD2-CD1 4.45Å; Y207-L211 HydrophobicContact CD2-CG 4.18Å; Y207-L211 HydrophobicContact CE1-CD1 3.9Å; Y207-L211 HydrophobicContact CE2-CD1 3.81Å; Y207-L211 HydrophobicContact CE2-CD2 4.1Å; Y207-L211 HydrophobicContact CE2-CG 3.7Å; Y207-L211 PolarHBondContact O-N 3.43Å; Y207-L211 VanDerWaalsContact O-N 3.12Å; Y207-Q222 HydrophobicContact CE1-CG 4.38Å; Y207-F223 AromaticContact CD1-CE2 3.93Å; Y207-F223 HydrophobicContact CD1-CE2 3.93Å; Y207-F223 AromaticContact CD1-CZ 3.68Å; Y207-F223 HydrophobicContact CD1-CZ 3.68Å; Y207-F223 HydrophobicContact CE1-CE2 4.18Å; Y207-F223 HydrophobicContact CE1-CZ 4.18Å
208M96.8Very high96.7Very high0 Ų062.8 Ų62.80%031%0.311CS..Hα-helixtrans-64.4-49.7171.7-71.7172.364.600110.6V204 A205 L211 M212 Y219 F223 F226 P233 V236V204-M208 HydrophobicContact CG1-SD 4.43Å; V204-M208 VanDerWaalsContact O-CG 3.28Å; V204-M208 WeakPolarHBondContact O-CG 3.5Å; V204-M208 PolarHBondContact O-N 2.87Å; A205-M208 WeakPolarHBondContact O-CA 3.4Å; A205-M208 WeakPolarHBondContact O-CB 3.48Å; A205-M208 PolarHBondContact O-N 2.89Å; M208-L211 PolarHBondContact O-N 2.89Å; M208-M212 VanDerWaalsContact O-CG 3.27Å; M208-M212 WeakPolarHBondContact O-CG 3.45Å; M208-M212 PolarHBondContact O-N 3.06Å; M208-Y219 HydrophobicContact CB-CE2 4.04Å; M208-Y219 HydrophobicContact CE-CE2 4.21Å; M208-Y219 HydrophobicContact CG-CE2 4.27Å; M208-F223 HydrophobicContact CB-CE2 4.24Å; M208-F223 HydrophobicContact CB-CZ 4.41Å; M208-F223 HydrophobicContact CG-CD1 3.76Å; M208-F223 HydrophobicContact CG-CD2 3.8Å; M208-F223 HydrophobicContact CG-CE1 3.49Å; M208-F223 VanDerWaalsContact CG-CE1 3.49Å; M208-F223 HydrophobicContact CG-CE2 3.5Å; M208-F223 VanDerWaalsContact CG-CE2 3.5Å; M208-F223 HydrophobicContact CG-CG 3.9Å; M208-F223 HydrophobicContact CG-CZ 3.34Å; M208-F223 HydrophobicContact SD-CD1 4.14Å; M208-F223 HydrophobicContact SD-CE1 4.09Å; M208-F223 HydrophobicContact SD-CZ 4.5Å; M208-F226 HydrophobicContact CE-CB 4.18Å; M208-F226 HydrophobicContact CE-CD1 4.02Å; M208-F226 HydrophobicContact CE-CG 4.38Å; M208-F226 HydrophobicContact SD-CD1 3.89Å; M208-F226 HydrophobicContact SD-CE1 4.22Å; M208-F226 HydrophobicContact SD-CG 4.5Å; M208-P233 HydrophobicContact CB-CB 4.42Å; M208-P233 HydrophobicContact CB-CG 3.79Å; M208-P233 HydrophobicContact CE-CG 4.29Å; M208-V236 HydrophobicContact SD-CG2 4.39Å
209S96.8Very high96.6Very high41 Ų4161.6 Ų61.629%0.28730%0.304SS..Hα-helixtrans-60.7-46.7178.7-57.90000111.8A205 D206 L211 M212 E213 P233A205-S209 PolarHBondContact O-N 2.58Å; A205-S209 PolarHBondContact O-OG 2.75Å; D206-S209 PolarHBondContact O-N 2.73Å; S209-L211 PolarHBondContact O-N 3.43Å; S209-M212 WeakPolarHBondContact O-CB 3Å; S209-M212 PolarHBondContact O-N 2.95Å; S209-M212 VanDerWaalsContact O-N 3.13Å; S209-E213 PolarHBondContact O-N 2.72Å; S209-E213 VanDerWaalsContact O-N 3.14Å; S209-P233 VanDerWaalsContact OG-CB 3.3Å; S209-P233 WeakPolarHBondContact OG-CB 3.34Å; S209-P233 WeakPolarHBondContact OG-CG 3.23Å
210Y97.3Very high96.5Very high128 Ų12865.9 Ų65.950%0.50232%0.323SS..Hα-helixtrans-55.6-48176172.6-102.7000112.4D206 Y207 M212 E213 E214D206-Y210 WeakPolarHBondContact O-CB 3.4Å; D206-Y210 PolarHBondContact O-N 2.86Å; Y207-Y210 HydrophobicContact CD2-CD1 4.15Å; Y207-Y210 HydrophobicContact CE2-CD1 4.27Å; Y210-M212 VanDerWaalsContact C-N 3.34Å; Y210-M212 PolarHBondContact O-N 3.26Å; Y210-E213 PolarHBondContact O-N 3.48Å; Y210-E214 HydrophobicContact CD2-CG 3.89Å; Y210-E214 HydrophobicContact CE1-CG 4.38Å; Y210-E214 HydrophobicContact CE2-CG 3.48Å; Y210-E214 VanDerWaalsContact CE2-CG 3.48Å; Y210-E214 HydrophobicContact CG-CG 4.5Å; Y210-E214 WeakPolarHBondContact O-CB 3.37Å; Y210-E214 WeakPolarHBondContact O-CG 3.41Å; Y210-E214 PolarHBondContact O-N 2.8Å
211L96.9Very high96.5Very high14 Ų1473.9 Ų73.97%0.07336%0.358CS..Hα-helixtrans-69.6-30.7178.2-76-175.8000113.1Y207 M208 S209 E213 D215 A218 Y219 Q222 F223Y207-L211 HydrophobicContact CD2-CD1 4.45Å; Y207-L211 HydrophobicContact CD2-CG 4.18Å; Y207-L211 HydrophobicContact CE1-CD1 3.9Å; Y207-L211 HydrophobicContact CE2-CD1 3.81Å; Y207-L211 HydrophobicContact CE2-CD2 4.1Å; Y207-L211 HydrophobicContact CE2-CG 3.7Å; Y207-L211 PolarHBondContact O-N 3.43Å; Y207-L211 VanDerWaalsContact O-N 3.12Å; M208-L211 PolarHBondContact O-N 2.89Å; S209-L211 PolarHBondContact O-N 3.43Å; L211-E213 VanDerWaalsContact C-N 3.26Å; L211-E213 PolarHBondContact O-N 2.79Å; L211-D215 CarbonylContact O-C 3.43Å; L211-D215 PolarHBondContact O-N 3.18Å; L211-A218 HydrophobicContact CD2-CB 4.26Å; L211-Y219 HydrophobicContact CB-CD2 4.3Å; L211-Q222 HydrophobicContact CD1-CB 4.43Å; L211-F223 HydrophobicContact CD1-CD2 4.37Å; L211-F223 HydrophobicContact CD1-CE2 3.97Å
212M94.1Very high96.5Very high92 Ų9279.6 Ų79.645%0.45338%0.384SS..Hα-helixtrans-63.7-35175.6-75.3175.161.100112.1M208 S209 Y210 Y219 P233M208-M212 VanDerWaalsContact O-CG 3.27Å; M208-M212 WeakPolarHBondContact O-CG 3.45Å; M208-M212 PolarHBondContact O-N 3.06Å; S209-M212 WeakPolarHBondContact O-CB 3Å; S209-M212 PolarHBondContact O-N 2.95Å; S209-M212 VanDerWaalsContact O-N 3.13Å; Y210-M212 VanDerWaalsContact C-N 3.34Å; Y210-M212 PolarHBondContact O-N 3.26Å; M212-Y219 HydrophobicContact CG-CD1 3.72Å; M212-Y219 HydrophobicContact CG-CD2 3.57Å; M212-Y219 HydrophobicContact CG-CE1 3.66Å; M212-Y219 HydrophobicContact CG-CE2 3.56Å; M212-Y219 HydrophobicContact CG-CG 3.67Å; M212-Y219 HydrophobicContact SD-CE1 4.05Å; M212-Y219 HydrophobicContact SD-CE2 3.9Å; M212-P233 HydrophobicContact SD-CG 3.95Å
213E95.4Very high96.5Very high164 Ų16477.7 Ų77.777%0.76637%0.374SS*.Hα-helixtrans-81.2-41.5179.3-68.3174.4-170.500112.3S209 Y210 L211S209-E213 PolarHBondContact O-N 2.72Å; S209-E213 VanDerWaalsContact O-N 3.14Å; Y210-E213 PolarHBondContact O-N 3.48Å; L211-E213 VanDerWaalsContact C-N 3.26Å; L211-E213 PolarHBondContact O-N 2.79Å
214E96.6Very high96.5Very high132 Ų13277.9 Ų77.962%0.61738%0.38SS*.Hα-helixtrans-89.7-40.4-172.2-65.2-78139.400114.2Y210Y210-E214 HydrophobicContact CD2-CG 3.89Å; Y210-E214 HydrophobicContact CE1-CG 4.38Å; Y210-E214 HydrophobicContact CE2-CG 3.48Å; Y210-E214 VanDerWaalsContact CE2-CG 3.48Å; Y210-E214 HydrophobicContact CG-CG 4.5Å; Y210-E214 WeakPolarHBondContact O-CB 3.37Å; Y210-E214 WeakPolarHBondContact O-CG 3.41Å; Y210-E214 PolarHBondContact O-N 2.8Å
215D95.8Very high96.5Very high77 Ų7784.7 Ų84.741%0.41240%0.403SS..  trans-154.791.6-174.1-174.2-16.6000111.7L211 D217 A218 Y219L211-D215 CarbonylContact O-C 3.43Å; L211-D215 PolarHBondContact O-N 3.18Å; D215-D217 PolarHBondContact O-N 3.01Å; D215-D217 PolarHBondContact OD1-N 3.09Å; D215-D217 VanDerWaalsContact OD1-N 3.09Å; D215-A218 HydrophobicContact CB-CB 3.89Å; D215-A218 PolarHBondContact O-N 2.82Å; D215-A218 PolarHBondContact OD1-N 2.91Å; D215-A218 WeakPolarHBondContact OD2-CB 3.47Å; D215-Y219 PolarHBondContact O-N 3.32Å
216E95.1Very high96.5Very high114 Ų11485.5 Ų85.553%0.53341%0.406SS..Hα-helixtrans-61.5-30.7-178.7-157.6-164158.100112.9Y219 K220E216-Y219 WeakPolarHBondContact O-CB 3.26Å; E216-Y219 PolarHBondContact O-N 3.5Å; E216-K220 VanDerWaalsContact O-CG 3.3Å; E216-K220 WeakPolarHBondContact O-CG 3.37Å; E216-K220 PolarHBondContact O-N 3.36Å; E216-K220 WeakPolarHBondContact OE1-CE 3.49Å; E216-K220 IonicContact OE1-NZ 2.67Å; E216-K220 PolarHBondContact OE1-NZ 3.09Å; E216-K220 IonicContact OE2-NZ 3.73Å
217D96Very high96.4Very high119 Ų11984.8 Ų84.864%0.63640%0.401SS*.Hα-helixtrans-73.6-41.7179.2-77.4-21.7000111D215 Y219 K220 K221D215-D217 PolarHBondContact O-N 3.01Å; D215-D217 PolarHBondContact OD1-N 3.09Å; D215-D217 VanDerWaalsContact OD1-N 3.09Å; D217-Y219 VanDerWaalsContact C-N 3.32Å; D217-K220 PolarHBondContact O-N 3.44Å; D217-K221 WeakPolarHBondContact O-CB 3.37Å; D217-K221 PolarHBondContact O-N 2.9Å
218A96.4Very high96.3Very high30 Ų3088.2 Ų88.225%0.24842%0.418CS..Hα-helixtrans-62.3-40.7170.800000111.5L211 D215 K221 Q222L211-A218 HydrophobicContact CD2-CB 4.26Å; D215-A218 HydrophobicContact CB-CB 3.89Å; D215-A218 PolarHBondContact O-N 2.82Å; D215-A218 PolarHBondContact OD1-N 2.91Å; D215-A218 WeakPolarHBondContact OD2-CB 3.47Å; A218-K221 PolarHBondContact O-N 3.07Å; A218-Q222 VanDerWaalsContact O-CB 3.3Å; A218-Q222 WeakPolarHBondContact O-CB 3.11Å; A218-Q222 PolarHBondContact O-N 3.36Å
219Y96.5Very high96.3Very high23 Ų2391.9 Ų91.99%0.0944%0.438CS..Hα-helixtrans-57.8-53.3174174.8-109.9000111.6M208 L211 M212 D215 E216 D217 K221 Q222 F223 I227M208-Y219 HydrophobicContact CB-CE2 4.04Å; M208-Y219 HydrophobicContact CE-CE2 4.21Å; M208-Y219 HydrophobicContact CG-CE2 4.27Å; L211-Y219 HydrophobicContact CB-CD2 4.3Å; M212-Y219 HydrophobicContact CG-CD1 3.72Å; M212-Y219 HydrophobicContact CG-CD2 3.57Å; M212-Y219 HydrophobicContact CG-CE1 3.66Å; M212-Y219 HydrophobicContact CG-CE2 3.56Å; M212-Y219 HydrophobicContact CG-CG 3.67Å; M212-Y219 HydrophobicContact SD-CE1 4.05Å; M212-Y219 HydrophobicContact SD-CE2 3.9Å; D215-Y219 PolarHBondContact O-N 3.32Å; E216-Y219 WeakPolarHBondContact O-CB 3.26Å; E216-Y219 PolarHBondContact O-N 3.5Å; D217-Y219 VanDerWaalsContact C-N 3.32Å; Y219-K221 VanDerWaalsContact C-N 3.28Å; Y219-K221 PolarHBondContact O-N 3.38Å; Y219-Q222 PolarHBondContact O-N 3.05Å; Y219-F223 HydrophobicContact CD2-CB 4.18Å; Y219-F223 AromaticContact CD2-CD2 3.61Å; Y219-F223 HydrophobicContact CD2-CD2 3.61Å; Y219-F223 HydrophobicContact CD2-CE2 4.43Å; Y219-F223 HydrophobicContact CD2-CG 4.29Å; Y219-F223 HydrophobicContact CE2-CB 3.89Å; Y219-F223 AromaticContact CE2-CD2 3.82Å; Y219-F223 HydrophobicContact CE2-CD2 3.82Å; Y219-F223 HydrophobicContact CE2-CG 4.13Å; Y219-F223 WeakPolarHBondContact O-CB 3.37Å; Y219-F223 PolarHBondContact O-N 2.95Å; Y219-I227 HydrophobicContact CD1-CD1 4.04Å; Y219-I227 HydrophobicContact CE1-CD1 3.65Å; Y219-I227 HydrophobicContact CE1-CG1 3.91Å
220K96.4Very high96.1Very high91 Ų9192.7 Ų92.740%0.39645%0.453SS..Hα-helixtrans-57.4-41177.8-74.6166.1-175.21580111.8E216 D217 S224 I227E216-K220 VanDerWaalsContact O-CG 3.3Å; E216-K220 WeakPolarHBondContact O-CG 3.37Å; E216-K220 PolarHBondContact O-N 3.36Å; E216-K220 WeakPolarHBondContact OE1-CE 3.49Å; E216-K220 IonicContact OE1-NZ 2.67Å; E216-K220 PolarHBondContact OE1-NZ 3.09Å; E216-K220 IonicContact OE2-NZ 3.73Å; D217-K220 PolarHBondContact O-N 3.44Å; K220-S224 VanDerWaalsContact O-CA 3.23Å; K220-S224 WeakPolarHBondContact O-CA 3.35Å; K220-S224 WeakPolarHBondContact O-CB 3.48Å; K220-S224 PolarHBondContact O-N 2.58Å; K220-I227 HydrophobicContact CB-CD1 4.47Å; K220-I227 HydrophobicContact CG-CD1 4.14Å
221K97.2Very high96Very high176 Ų17687.3 Ų87.377%0.76543%0.433SS*.Hα-helixtrans-66.5-51.1179-175.6178.2179.8179.50112.2D217 A218 Y219D217-K221 WeakPolarHBondContact O-CB 3.37Å; D217-K221 PolarHBondContact O-N 2.9Å; A218-K221 PolarHBondContact O-N 3.07Å; Y219-K221 VanDerWaalsContact C-N 3.28Å; Y219-K221 PolarHBondContact O-N 3.38Å
222Q96.7Very high95.9Very high121 Ų12189.6 Ų89.657%0.56545%0.448SS*.Hα-helixtrans-71.5-43.9-175.2-176.866.5-0.700112Y207 L211 A218 Y219Y207-Q222 HydrophobicContact CE1-CG 4.38Å; L211-Q222 HydrophobicContact CD1-CB 4.43Å; A218-Q222 VanDerWaalsContact O-CB 3.3Å; A218-Q222 WeakPolarHBondContact O-CB 3.11Å; A218-Q222 PolarHBondContact O-N 3.36Å; Y219-Q222 PolarHBondContact O-N 3.05Å
223F97.2Very high96Very high12 Ų1285.8 Ų85.85%0.05343%0.43CS..Hα-helixtrans-108.518-171.5-65.6-70.7000113.9V204 Y207 M208 L211 Y219 R225 F226 I227V204-F223 HydrophobicContact CG1-CE1 3.97Å; V204-F223 HydrophobicContact CG1-CZ 4.35Å; Y207-F223 AromaticContact CD1-CE2 3.93Å; Y207-F223 HydrophobicContact CD1-CE2 3.93Å; Y207-F223 AromaticContact CD1-CZ 3.68Å; Y207-F223 HydrophobicContact CD1-CZ 3.68Å; Y207-F223 HydrophobicContact CE1-CE2 4.18Å; Y207-F223 HydrophobicContact CE1-CZ 4.18Å; M208-F223 HydrophobicContact CB-CE2 4.24Å; M208-F223 HydrophobicContact CB-CZ 4.41Å; M208-F223 HydrophobicContact CG-CD1 3.76Å; M208-F223 HydrophobicContact CG-CD2 3.8Å; M208-F223 HydrophobicContact CG-CE1 3.49Å; M208-F223 VanDerWaalsContact CG-CE1 3.49Å; M208-F223 HydrophobicContact CG-CE2 3.5Å; M208-F223 VanDerWaalsContact CG-CE2 3.5Å; M208-F223 HydrophobicContact CG-CG 3.9Å; M208-F223 HydrophobicContact CG-CZ 3.34Å; M208-F223 HydrophobicContact SD-CD1 4.14Å; M208-F223 HydrophobicContact SD-CE1 4.09Å; M208-F223 HydrophobicContact SD-CZ 4.5Å; L211-F223 HydrophobicContact CD1-CD2 4.37Å; L211-F223 HydrophobicContact CD1-CE2 3.97Å; Y219-F223 HydrophobicContact CD2-CB 4.18Å; Y219-F223 AromaticContact CD2-CD2 3.61Å; Y219-F223 HydrophobicContact CD2-CD2 3.61Å; Y219-F223 HydrophobicContact CD2-CE2 4.43Å; Y219-F223 HydrophobicContact CD2-CG 4.29Å; Y219-F223 HydrophobicContact CE2-CB 3.89Å; Y219-F223 AromaticContact CE2-CD2 3.82Å; Y219-F223 HydrophobicContact CE2-CD2 3.82Å; Y219-F223 HydrophobicContact CE2-CG 4.13Å; Y219-F223 WeakPolarHBondContact O-CB 3.37Å; Y219-F223 PolarHBondContact O-N 2.95Å; F223-R225 PolarHBondContact O-N 2.93Å; F223-F226 HydrophobicContact CB-CB 4.21Å; F223-F226 AromaticContact CD1-CD2 3.79Å; F223-F226 HydrophobicContact CD1-CD2 3.79Å; F223-F226 HydrophobicContact CD1-CE2 4.1Å; F223-F226 HydrophobicContact CD1-CG 4.12Å; F223-F226 WeakPolarHBondContact O-CA 3.18Å; F223-F226 WeakPolarHBondContact O-CB 3.28Å; F223-F226 PolarHBondContact O-N 3.33Å; F223-I227 PolarHBondContact O-N 3.28Å
224S96.9Very high95.9Very high65 Ų6584.8 Ų84.846%0.45543%0.43SS..Hα-helixtrans-43.2-40.5176.552.40000114.8K220 K228K220-S224 VanDerWaalsContact O-CA 3.23Å; K220-S224 WeakPolarHBondContact O-CA 3.35Å; K220-S224 WeakPolarHBondContact O-CB 3.48Å; K220-S224 PolarHBondContact O-N 2.58Å; S224-K228 WeakPolarHBondContact O-CB 3.34Å; S224-K228 PolarHBondContact O-N 3.46Å
225R96.3Very high95.9Very high173 Ų17381 Ų8165%0.65342%0.416SS*.Hα-helixtrans-73.9-32.4177.8-67.8-172.9178.1-163.1-2.5113.5V90 F223 N229V90-R225 HydrophobicContact CG1-CB 4.02Å; F223-R225 PolarHBondContact O-N 2.93Å; R225-N229 PolarHBondContact O-N 3.33Å; R225-N229 PolarHBondContact O-ND2 3.04Å
226F96.4Very high95.9Very high21 Ų2177.4 Ų77.49%0.09240%0.397CS..Hα-helixtrans-66.7-47.2174.8-77.2-110.9000109.5V90 M208 F223 K228 N229 G230 V231V90-F226 HydrophobicContact CB-CD2 4.18Å; V90-F226 HydrophobicContact CB-CE2 4.03Å; V90-F226 HydrophobicContact CB-CZ 4.26Å; V90-F226 HydrophobicContact CG2-CD1 3.73Å; V90-F226 HydrophobicContact CG2-CD2 3.94Å; V90-F226 HydrophobicContact CG2-CE1 3.67Å; V90-F226 HydrophobicContact CG2-CE2 3.89Å; V90-F226 HydrophobicContact CG2-CG 3.86Å; V90-F226 HydrophobicContact CG2-CZ 3.75Å; M208-F226 HydrophobicContact CE-CB 4.18Å; M208-F226 HydrophobicContact CE-CD1 4.02Å; M208-F226 HydrophobicContact CE-CG 4.38Å; M208-F226 HydrophobicContact SD-CD1 3.89Å; M208-F226 HydrophobicContact SD-CE1 4.22Å; M208-F226 HydrophobicContact SD-CG 4.5Å; F223-F226 HydrophobicContact CB-CB 4.21Å; F223-F226 AromaticContact CD1-CD2 3.79Å; F223-F226 HydrophobicContact CD1-CD2 3.79Å; F223-F226 HydrophobicContact CD1-CE2 4.1Å; F223-F226 HydrophobicContact CD1-CG 4.12Å; F223-F226 WeakPolarHBondContact O-CA 3.18Å; F223-F226 WeakPolarHBondContact O-CB 3.28Å; F223-F226 PolarHBondContact O-N 3.33Å; F226-K228 PolarHBondContact O-N 3.36Å; F226-N229 CarbonylContact O-C 3.58Å; F226-N229 PolarHBondContact O-N 3.41Å; F226-N229 VanDerWaalsContact O-N 3.08Å; F226-G230 PolarHBondContact O-N 3.29Å; F226-V231 HydrophobicContact CB-CB 4.28Å; F226-V231 HydrophobicContact CD1-CB 3.84Å; F226-V231 HydrophobicContact CD1-CG1 3.65Å; F226-V231 HydrophobicContact CE1-CG1 4.17Å; F226-V231 HydrophobicContact CG-CB 4.47Å; F226-V231 PolarHBondContact O-N 3.35Å
227I95.7Very high95.9Very high78 Ų7874.3 Ų74.340%0.438%0.382SS..Hα-helixtrans-56.1-49.1174.5-58.7169.3000110.6Y219 K220 F223 N229 G230Y219-I227 HydrophobicContact CD1-CD1 4.04Å; Y219-I227 HydrophobicContact CE1-CD1 3.65Å; Y219-I227 HydrophobicContact CE1-CG1 3.91Å; K220-I227 HydrophobicContact CB-CD1 4.47Å; K220-I227 HydrophobicContact CG-CD1 4.14Å; F223-I227 PolarHBondContact O-N 3.28Å; I227-N229 PolarHBondContact O-N 3.1Å; I227-G230 PolarHBondContact O-N 3.07Å
228K96.7Very high95.9Very high181 Ų18173.5 Ų73.579%0.78738%0.375SS*.Hα-helixtrans-58.8-31178.9-177.3174179.8175.80113.7S224 F226S224-K228 WeakPolarHBondContact O-CB 3.34Å; S224-K228 PolarHBondContact O-N 3.46Å; F226-K228 PolarHBondContact O-N 3.36Å
229N95Very high95.9Very high78 Ų7873.2 Ų73.242%0.41737%0.369SS..THydrogen-bonded Turntrans-100.69.6-179.8-67.5-74000112.9V90 R225 F226 I227 V231V90-N229 HydrophobicContact CG1-CB 4.29Å; V90-N229 WeakPolarHBondContact CG1-ND2 3.18Å; R225-N229 PolarHBondContact O-N 3.33Å; R225-N229 PolarHBondContact O-ND2 3.04Å; F226-N229 CarbonylContact O-C 3.58Å; F226-N229 PolarHBondContact O-N 3.41Å; F226-N229 VanDerWaalsContact O-N 3.08Å; I227-N229 PolarHBondContact O-N 3.1Å; N229-V231 VanDerWaalsContact C-N 3.31Å; N229-V231 HydrophobicContact CB-CG2 4.39Å; N229-V231 PolarHBondContact O-N 3.49Å
230G94Very high96Very high58 Ų5872.2 Ų72.260%0.59836%0.364SS*.THydrogen-bonded Turntrans66.926.2177.400000114.8F226 I227F226-G230 PolarHBondContact O-N 3.29Å; I227-G230 PolarHBondContact O-N 3.07Å
231V95.1Very high96Very high15 Ų1572.3 Ų72.39%0.09137%0.365CS..  trans-91.1113.6178.2-176.20000109.3V90 F226 N229 V236 M239V90-V231 HydrophobicContact CG2-CG2 4.04Å; F226-V231 HydrophobicContact CB-CB 4.28Å; F226-V231 HydrophobicContact CD1-CB 3.84Å; F226-V231 HydrophobicContact CD1-CG1 3.65Å; F226-V231 HydrophobicContact CE1-CG1 4.17Å; F226-V231 HydrophobicContact CG-CB 4.47Å; F226-V231 PolarHBondContact O-N 3.35Å; N229-V231 VanDerWaalsContact C-N 3.31Å; N229-V231 HydrophobicContact CB-CG2 4.39Å; N229-V231 PolarHBondContact O-N 3.49Å; V231-V236 HydrophobicContact CG1-CG2 4.05Å; V231-M239 HydrophobicContact CG1-SD 4.49Å; V231-M239 HydrophobicContact CG2-SD 4.41Å
232T94.7Very high96Very high61 Ų6169.8 Ų69.837%0.37435%0.354SS..  trans-100.3161.9175.265.80000110.8D234 T235 V236T232-D234 VanDerWaalsContact C-N 3.29Å; T232-D234 PolarHBondContact O-N 2.86Å; T232-T235 PolarHBondContact N-OG1 3.23Å; T232-T235 VanDerWaalsContact N-OG1 3.08Å; T232-T235 PolarHBondContact O-N 2.89Å; T232-T235 VanDerWaalsContact O-N 3.13Å; T232-T235 PolarHBondContact O-OG1 3.3Å; T232-T235 VanDerWaalsContact OG1-CG2 3.32Å; T232-T235 WeakPolarHBondContact OG1-CG2 3.46Å; T232-T235 PolarHBondContact OG1-OG1 3.27Å; T232-V236 WeakPolarHBondContact O-CG2 3.4Å
233P95Very high96.1Very high13 Ų1364 Ų648%0.08433%0.327CS..THydrogen-bonded Turntrans-50.9-46.3179.6-25.733.6000113.4A205 M208 S209 M212 T235 V236A205-P233 HydrophobicContact CB-CB 4.14Å; A205-P233 WeakPolarHBondContact CB-O 3.24Å; M208-P233 HydrophobicContact CB-CB 4.42Å; M208-P233 HydrophobicContact CB-CG 3.79Å; M208-P233 HydrophobicContact CE-CG 4.29Å; S209-P233 VanDerWaalsContact OG-CB 3.3Å; S209-P233 WeakPolarHBondContact OG-CB 3.34Å; S209-P233 WeakPolarHBondContact OG-CG 3.23Å; M212-P233 HydrophobicContact SD-CG 3.95Å; P233-T235 VanDerWaalsContact C-N 3.27Å; P233-T235 PolarHBondContact O-N 2.77Å; P233-V236 WeakPolarHBondContact O-CB 3.36Å; P233-V236 WeakPolarHBondContact O-CG2 3.4Å; P233-V236 PolarHBondContact O-N 3.02Å
234D94.8Very high96.1Very high142 Ų14263.7 Ų63.776%0.75933%0.326SS*.THydrogen-bonded Turntrans-64.9-29.8-176.7-51.5-41.4000113.2T232T232-D234 VanDerWaalsContact C-N 3.29Å; T232-D234 PolarHBondContact O-N 2.86Å
235T95.6Very high96.1Very high53 Ų5363.5 Ų63.533%0.32533%0.328SS..Hα-helixtrans-83-12-177.362.30000113.6T232 P233 E237 E238 M239T232-T235 PolarHBondContact N-OG1 3.23Å; T232-T235 VanDerWaalsContact N-OG1 3.08Å; T232-T235 PolarHBondContact O-N 2.89Å; T232-T235 VanDerWaalsContact O-N 3.13Å; T232-T235 PolarHBondContact O-OG1 3.3Å; T232-T235 VanDerWaalsContact OG1-CG2 3.32Å; T232-T235 WeakPolarHBondContact OG1-CG2 3.46Å; T232-T235 PolarHBondContact OG1-OG1 3.27Å; P233-T235 VanDerWaalsContact C-N 3.27Å; P233-T235 PolarHBondContact O-N 2.77Å; T235-E237 PolarHBondContact O-N 3.44Å; T235-E238 PolarHBondContact O-N 3.23Å; T235-M239 WeakPolarHBondContact O-CB 3.3Å; T235-M239 PolarHBondContact O-N 3.1Å
236V95.8Very high96.2Very high2 Ų257 Ų571%0.01231%0.311CS..Hα-helixtrans-62.3-45.3-173.4176.10000111.7A205 M208 V231 T232 P233 M239 Y240A205-V236 HydrophobicContact CB-CB 4.19Å; A205-V236 HydrophobicContact CB-CG2 4.18Å; M208-V236 HydrophobicContact SD-CG2 4.39Å; V231-V236 HydrophobicContact CG1-CG2 4.05Å; T232-V236 WeakPolarHBondContact O-CG2 3.4Å; P233-V236 WeakPolarHBondContact O-CB 3.36Å; P233-V236 WeakPolarHBondContact O-CG2 3.4Å; P233-V236 PolarHBondContact O-N 3.02Å; V236-M239 WeakPolarHBondContact O-CB 3.08Å; V236-M239 PolarHBondContact O-N 3.45Å; V236-Y240 HydrophobicContact CG1-CD2 3.98Å; V236-Y240 HydrophobicContact CG1-CE2 3.73Å; V236-Y240 VanDerWaalsContact O-CD2 3.24Å; V236-Y240 WeakPolarHBondContact O-CD2 3.32Å; V236-Y240 PolarHBondContact O-N 3.31Å
237E95.3Very high96.3Very high49 Ų4956 Ų5623%0.22931%0.307CS..Hα-helixtrans-63.5-46.3-179.5-177174.7-18000111.5M200 M202 T235 M239 Y240 K241M200-E237 HydrophobicContact CB-CG 4.12Å; M200-E237 HydrophobicContact CG-CG 4.33Å; M202-E237 HydrophobicContact SD-CB 3.74Å; M202-E237 HydrophobicContact SD-CG 4.27Å; T235-E237 PolarHBondContact O-N 3.44Å; E237-M239 VanDerWaalsContact C-N 3.31Å; E237-M239 PolarHBondContact O-N 3.11Å; E237-Y240 PolarHBondContact O-N 3Å; E237-K241 VanDerWaalsContact CD-NZ 3.31Å; E237-K241 HydrophobicContact CG-CD 4.17Å; E237-K241 WeakPolarHBondContact O-CG 3.3Å; E237-K241 PolarHBondContact O-N 3.19Å; E237-K241 WeakPolarHBondContact OE1-CE 3.5Å; E237-K241 IonicContact OE1-NZ 2.66Å; E237-K241 PolarHBondContact OE1-NZ 3.5Å
238E96Very high96.3Very high102 Ų10254.6 Ų54.648%0.47730%0.296SS..Hα-helixtrans-64.6-37.5-179.8-161.5-169175.100111.5T235 Y240 K241 K242T235-E238 PolarHBondContact O-N 3.23Å; E238-Y240 PolarHBondContact O-N 3.45Å; E238-K241 PolarHBondContact O-N 3.32Å; E238-K242 HydrophobicContact CG-CD 4.31Å; E238-K242 WeakPolarHBondContact O-CB 3.37Å; E238-K242 WeakPolarHBondContact O-CG 3.42Å; E238-K242 PolarHBondContact O-N 3.49Å; E238-K242 WeakPolarHBondContact OE1-CE 3.35Å; E238-K242 IonicContact OE1-NZ 2.65Å; E238-K242 PolarHBondContact OE1-NZ 3.28Å; E238-K242 IonicContact OE2-NZ 3.56Å
239M97.1Very high96.4Very high24 Ų2450.1 Ų50.112%0.11829%0.293CS..Hα-helixtrans-57.1-47.8174.7-179.1-173.360.700111.4V231 T235 V236 E237 A243V231-M239 HydrophobicContact CG1-SD 4.49Å; V231-M239 HydrophobicContact CG2-SD 4.41Å; T235-M239 WeakPolarHBondContact O-CB 3.3Å; T235-M239 PolarHBondContact O-N 3.1Å; V236-M239 WeakPolarHBondContact O-CB 3.08Å; V236-M239 PolarHBondContact O-N 3.45Å; E237-M239 VanDerWaalsContact C-N 3.31Å; E237-M239 PolarHBondContact O-N 3.11Å; M239-A243 WeakPolarHBondContact O-CB 3.4Å; M239-A243 PolarHBondContact O-N 2.75Å
240Y97.8Very high96.4Very high1 Ų150.1 Ų50.10%0.00429%0.293CS..Hα-helixtrans-71.2-38178.6-73.5-68.1000112.7I88 N94 A96 M200 V236 E237 E238 K242 A243 H244I88-Y240 HydrophobicContact CD1-CD1 3.7Å; I88-Y240 HydrophobicContact CD1-CE1 3.69Å; I88-Y240 HydrophobicContact CG1-CD1 4.16Å; I88-Y240 HydrophobicContact CG1-CE1 4.07Å; I88-Y240 HydrophobicContact CG2-CE1 4.12Å; N94-Y240 PolarHBondContact ND2-OH 3.12Å; A96-Y240 HydrophobicContact CB-CD1 3.87Å; A96-Y240 HydrophobicContact CB-CD2 4.01Å; A96-Y240 HydrophobicContact CB-CE1 3.49Å; A96-Y240 VanDerWaalsContact CB-CE1 3.49Å; A96-Y240 HydrophobicContact CB-CE2 3.66Å; A96-Y240 HydrophobicContact CB-CG 4.13Å; M200-Y240 WeakPolarHBondContact O-CD2 3.36Å; V236-Y240 HydrophobicContact CG1-CD2 3.98Å; V236-Y240 HydrophobicContact CG1-CE2 3.73Å; V236-Y240 VanDerWaalsContact O-CD2 3.24Å; V236-Y240 WeakPolarHBondContact O-CD2 3.32Å; V236-Y240 PolarHBondContact O-N 3.31Å; E237-Y240 PolarHBondContact O-N 3Å; E238-Y240 PolarHBondContact O-N 3.45Å; Y240-K242 PolarHBondContact O-N 3.29Å; Y240-A243 WeakPolarHBondContact O-CB 2.99Å; Y240-A243 PolarHBondContact O-N 3.32Å; Y240-H244 PolarHBondContact O-CD2 3.27Å; Y240-H244 VanDerWaalsContact O-CD2 3.25Å; Y240-H244 PolarHBondContact O-N 2.9Å
241K96.9Very high96.4Very high94 Ų9447.7 Ų47.741%0.40927%0.267SS..Hα-helixtrans-57.6-48.1173.2-77.1174.7178.3165.70111.8M200 E237 E238 A243 H244 A245M200-K241 HydrophobicContact CE-CG 4.22Å; M200-K241 HydrophobicContact SD-CG 4.18Å; E237-K241 VanDerWaalsContact CD-NZ 3.31Å; E237-K241 HydrophobicContact CG-CD 4.17Å; E237-K241 WeakPolarHBondContact O-CG 3.3Å; E237-K241 PolarHBondContact O-N 3.19Å; E237-K241 WeakPolarHBondContact OE1-CE 3.5Å; E237-K241 IonicContact OE1-NZ 2.66Å; E237-K241 PolarHBondContact OE1-NZ 3.5Å; E238-K241 PolarHBondContact O-N 3.32Å; K241-A243 VanDerWaalsContact C-N 3.31Å; K241-A243 PolarHBondContact O-N 3.02Å; K241-H244 PolarHBondContact O-N 3.1Å; K241-A245 PolarHBondContact O-N 3.21Å; K241-A245 VanDerWaalsContact O-N 3.15Å
242K97.1Very high96.4Very high122 Ų12250.1 Ų50.153%0.5328%0.282SS..Hα-helixtrans-60.6-41.1175.1-74.6174.2-179.9163.70111.5E238 Y240 A245 A246E238-K242 HydrophobicContact CG-CD 4.31Å; E238-K242 WeakPolarHBondContact O-CB 3.37Å; E238-K242 WeakPolarHBondContact O-CG 3.42Å; E238-K242 PolarHBondContact O-N 3.49Å; E238-K242 WeakPolarHBondContact OE1-CE 3.35Å; E238-K242 IonicContact OE1-NZ 2.65Å; E238-K242 PolarHBondContact OE1-NZ 3.28Å; E238-K242 IonicContact OE2-NZ 3.56Å; Y240-K242 PolarHBondContact O-N 3.29Å; K242-A245 PolarHBondContact O-N 3.17Å; K242-A246 WeakPolarHBondContact O-CB 3.41Å; K242-A246 PolarHBondContact O-N 3.4Å
243A97.7Very high96.2Very high0 Ų051.2 Ų51.20%028%0.283CS..Hα-helixtrans-64.4-41.3177.500000112.8Y86 I88 M239 Y240 K241 A245 A246 I247Y86-A243 VanDerWaalsContact O-CA 3.26Å; Y86-A243 WeakPolarHBondContact O-CA 3.42Å; Y86-A243 WeakPolarHBondContact O-CB 3.49Å; I88-A243 HydrophobicContact CD1-CB 3.51Å; I88-A243 HydrophobicContact CG1-CB 3.6Å; M239-A243 WeakPolarHBondContact O-CB 3.4Å; M239-A243 PolarHBondContact O-N 2.75Å; Y240-A243 WeakPolarHBondContact O-CB 2.99Å; Y240-A243 PolarHBondContact O-N 3.32Å; K241-A243 VanDerWaalsContact C-N 3.31Å; K241-A243 PolarHBondContact O-N 3.02Å; A243-A245 VanDerWaalsContact C-N 3.34Å; A243-A245 PolarHBondContact O-N 2.96Å; A243-A246 PolarHBondContact O-N 3.49Å; A243-I247 WeakPolarHBondContact O-CB 3.42Å; A243-I247 WeakPolarHBondContact O-CD1 3.32Å; A243-I247 WeakPolarHBondContact O-CG1 3.28Å; A243-I247 PolarHBondContact O-N 2.88Å
244H98.1Very high95.9Very high6 Ų656.9 Ų56.93%0.02831%0.308CS..Hα-helixtrans-60.7-43.9175.5-61.2165.4000111.5Y99 C100 L103 Y240 K241 I247 R248Y99-H244 AromaticContact CD1-CE1 3.89Å; Y99-H244 AromaticContact CD1-NE2 3.48Å; Y99-H244 WeakPolarHBondContact CD1-NE2 3.3Å; Y99-H244 AromaticContact CE1-CE1 3.65Å; Y99-H244 AromaticContact CE1-NE2 3.59Å; C100-H244 VanDerWaalsContact SG-CD2 3.57Å; C100-H244 PolarHBondContact SG-NE2 2.97Å; C100-H244 VanDerWaalsContact SG-NE2 3.38Å; L103-H244 HydrophobicContact CD2-CB 4.09Å; Y240-H244 PolarHBondContact O-CD2 3.27Å; Y240-H244 VanDerWaalsContact O-CD2 3.25Å; Y240-H244 PolarHBondContact O-N 2.9Å; K241-H244 PolarHBondContact O-N 3.1Å; H244-I247 PolarHBondContact O-N 2.89Å; H244-R248 WeakPolarHBondContact O-CG 3.42Å; H244-R248 PolarHBondContact O-N 3.23Å; H244-R248 VanDerWaalsContact O-N 3.14Å
245A98Very high95.7Very high61 Ų6159 Ų5950%0.50431%0.31SS..Hα-helixtrans-63-46.5175.500000111.8K241 K242 A243 I247 R248 A249K241-A245 PolarHBondContact O-N 3.21Å; K241-A245 VanDerWaalsContact O-N 3.15Å; K242-A245 PolarHBondContact O-N 3.17Å; A243-A245 VanDerWaalsContact C-N 3.34Å; A243-A245 PolarHBondContact O-N 2.96Å; A245-I247 VanDerWaalsContact C-N 3.35Å; A245-I247 PolarHBondContact O-N 3.43Å; A245-R248 PolarHBondContact O-N 3.02Å; A245-A249 WeakPolarHBondContact O-CB 3.37Å; A245-A249 PolarHBondContact O-N 3.11Å
246A97.9Very high95.4Very high36 Ų3665.2 Ų65.230%0.29833%0.333SS..Hα-helixtrans-62.3-39.6178.800000112.7Y86 K242 A243 A249 N250Y86-A246 HydrophobicContact CD1-CB 4.05Å; K242-A246 WeakPolarHBondContact O-CB 3.41Å; K242-A246 PolarHBondContact O-N 3.4Å; A243-A246 PolarHBondContact O-N 3.49Å; A246-A249 PolarHBondContact O-N 2.88Å; A246-N250 PolarHBondContact O-N 2.97Å
247I97.9Very high95.3Very high0 Ų070.5 Ų70.50%037%0.367CS..Hα-helixtrans-63.1-41.8175.9-73.1165.7000111.1L83 Y86 C100 L103 L104 R107 A243 H244 A245 N250L83-I247 HydrophobicContact CD2-CD1 4.2Å; Y86-I247 HydrophobicContact CD1-CG1 3.82Å; Y86-I247 HydrophobicContact CD2-CG1 4.04Å; Y86-I247 HydrophobicContact CE1-CG1 4.28Å; Y86-I247 HydrophobicContact CE2-CG1 4.49Å; Y86-I247 HydrophobicContact CG-CG1 3.68Å; C100-I247 HydrophobicContact CB-CD1 4.08Å; L103-I247 HydrophobicContact CD2-CG2 4.34Å; L103-I247 HydrophobicContact CG-CG2 4.02Å; L104-I247 HydrophobicContact CB-CD1 4.39Å; L104-I247 HydrophobicContact CB-CG2 3.96Å; L104-I247 HydrophobicContact CD1-CG1 4.46Å; L104-I247 HydrophobicContact CD1-CG2 3.97Å; R107-I247 HydrophobicContact CG-CG2 4.49Å; A243-I247 WeakPolarHBondContact O-CB 3.42Å; A243-I247 WeakPolarHBondContact O-CD1 3.32Å; A243-I247 WeakPolarHBondContact O-CG1 3.28Å; A243-I247 PolarHBondContact O-N 2.88Å; H244-I247 PolarHBondContact O-N 2.89Å; A245-I247 VanDerWaalsContact C-N 3.35Å; A245-I247 PolarHBondContact O-N 3.43Å; I247-N250 CarbonylContact O-C 3.58Å
248R96.8Very high95.1Very high48 Ų4876 Ų7618%0.18140%0.398CS..Hα-helixtrans-67.8-37.3176.9-72.6-174.8177111.32.9112R107 Q122 V123 H244 A245R107-R248 HydrophobicContact CG-CG 4.36Å; Q122-R248 PolarHBondContact O-NH2 3.22Å; V123-R248 PolarHBondContact O-NH1 3.32Å; H244-R248 WeakPolarHBondContact O-CG 3.42Å; H244-R248 PolarHBondContact O-N 3.23Å; H244-R248 VanDerWaalsContact O-N 3.14Å; A245-R248 PolarHBondContact O-N 3.02Å
249A97Very high94.9Very high87 Ų8779.7 Ų79.772%0.71941%0.413SS*.Hα-helixtrans-67.1-41.5179.200000112.9A245 A246A245-A249 WeakPolarHBondContact O-CB 3.37Å; A245-A249 PolarHBondContact O-N 3.11Å; A246-A249 PolarHBondContact O-N 2.88Å
250N95.4Very high94.5Very high79 Ų7986.9 Ų86.942%0.42245%0.452SS..  trans-144.190.1178.8-174.90.2000112.6Y86 A246 I247 V252Y86-N250 WeakPolarHBondContact CE1-O 3.24Å; Y86-N250 PolarHBondContact OH-O 3.3Å; A246-N250 PolarHBondContact O-N 2.97Å; I247-N250 CarbonylContact O-C 3.58Å; N250-V252 VanDerWaalsContact C-N 3.3Å; N250-V252 PolarHBondContact O-N 3.43Å; N250-V252 WeakPolarHBondContact OD1-CB 3.44Å; N250-V252 PolarHBondContact OD1-N 2.76Å; N250-V252 VanDerWaalsContact OD1-N 3.16Å
251P94.6Very high94.2Very high7 Ų792 Ų925%0.04548%0.483CS..  trans-84.4-0.8179.533.8-36000114L104 R107 R108 H111L104-P251 HydrophobicContact CD1-CB 4.42Å; R107-P251 HydrophobicContact CB-CB 3.7Å; R107-P251 HydrophobicContact CB-CG 4.15Å; R108-P251 HydrophobicContact CB-CB 4.24Å; R108-P251 PolarHBondContact NE-O 2.97Å; R108-P251 PolarHBondContact NH2-O 3.01Å; H111-P251 HydrophobicContact CB-CG 4.01Å
252V93.9Very high94Very high66 Ų6693.9 Ų93.940%0.450%0.502SS..  trans-70.6136.4-168.5-178.50000111.4N250N250-V252 VanDerWaalsContact C-N 3.3Å; N250-V252 PolarHBondContact O-N 3.43Å; N250-V252 WeakPolarHBondContact OD1-CB 3.44Å; N250-V252 PolarHBondContact OD1-N 2.76Å; N250-V252 VanDerWaalsContact OD1-N 3.16Å
253H92Very high93.7Very high84 Ų8498.4 Ų98.439%0.38952%0.522SS..  trans-91.7111.3174.9-177.184.2000111.4E82E82-H253 IonicContact OE1-CE1 3.27Å; E82-H253 PolarHBondContact OE1-CE1 3.05Å; E82-H253 VanDerWaalsContact OE1-CE1 3.27Å; E82-H253 IonicContact OE1-ND1 3.18Å; E82-H253 PolarHBondContact OE1-ND1 2.86Å; E82-H253 IonicContact OE2-ND1 3.3Å; E82-H253 PolarHBondContact OE2-ND1 3.2Å
254E89Confident93.5Very high131 Ų131105.3 Ų105.361%0.61255%0.552SS**PPolyproline II helixtrans-85.6117.9170.2-66.3175.2179.600111.1
255K89.8Confident93.2Very high186 Ų186113.2 Ų113.281%0.80958%0.582SS**PPolyproline II helixtrans-71.1133.7175.5-68.4-178.9-177.4173.60109.8
256K90.3Very high93Very high184 Ų184120.2 Ų120.280%0.860%0.595SS**PPolyproline II helixtrans-62.8142.4172.3-65-174.8-175.3-177.70109.9
257P91.8Very high93Very high114 Ų114124.8 Ų124.874%0.7462%0.615SS**PPolyproline II helixtrans-63.4144.4177.726.4-33.9000110.7
258N90.9Very high92.8Very high164 Ų164133.8 Ų133.888%0.87765%0.648SS**PPolyproline II helixtrans-67.8133.6173.8-73.4-28.4000109.3
259K91.8Very high92.7Very high179 Ų179133.9 Ų133.978%0.77866%0.66SS**PPolyproline II helixtrans-97.5134.5174.6-64.4-175.1177.4-171.40109.4V261K259-V261 HydrophobicContact CB-CG2 4.09Å; K259-V261 PolarHBondContact O-N 3.35Å
260D89.8Confident92.7Very high175 Ų175139.2 Ų139.294%0.93667%0.667SS**  trans-72.8113.5169.2-71.3-42000109.5
261V91.8Very high92.7Very high109 Ų109138 Ų13866%0.66166%0.66SS**  trans-127.8128.9-177.4-176.30000109.4K259 K263K259-V261 HydrophobicContact CB-CG2 4.09Å; K259-V261 PolarHBondContact O-N 3.35Å; V261-K263 PolarHBondContact O-N 3.08Å
262T91.6Very high92.9Very high134 Ų134140.3 Ų140.382%0.82268%0.676SS**  trans-64.5118.1170.655.90000110.2K264T262-K264 PolarHBondContact O-N 3.21Å
263K91.1Very high93.1Very high216 Ų216142.1 Ų142.194%0.93968%0.683SS**  trans-76.296.7-174.9-65.6-177.4-176.6172.40111.5V261V261-K263 PolarHBondContact O-N 3.08Å
264K93Very high93.4Very high146 Ų146140.8 Ų140.864%0.63569%0.686SS**  trans-81139.3168.6-172.3174179.7178.10111T262 W266T262-K264 PolarHBondContact O-N 3.21Å; K264-W266 HydrophobicContact CB-CZ2 4.39Å; K264-W266 HydrophobicContact CD-CH2 3.98Å; K264-W266 HydrophobicContact CD-CZ2 4.04Å; K264-W266 HydrophobicContact CD-CZ3 4.32Å; K264-W266 HydrophobicContact CG-CZ2 4.5Å
265R92.4Very high93.8Very high172 Ų172139.5 Ų139.565%0.64968%0.68SS**  trans-84.4116.7174-172.5-176.1-173.4142.420.8110.3N267 A269R265-N267 WeakPolarHBondContact CD-O 3.49Å; R265-N267 VanDerWaalsContact CG-O 3.28Å; R265-N267 WeakPolarHBondContact CG-O 3.32Å; R265-N267 PolarHBondContact NE-O 3.37Å; R265-A269 VanDerWaalsContact CZ-CA 3.47Å; R265-A269 VanDerWaalsContact NH2-CA 3.32Å
266W94.6Very high94.2Very high207 Ų207137.2 Ų137.278%0.78467%0.667SS**  trans-92.4-25.6176.9-58.5103000113.5K264K264-W266 HydrophobicContact CB-CZ2 4.39Å; K264-W266 HydrophobicContact CD-CH2 3.98Å; K264-W266 HydrophobicContact CD-CZ2 4.04Å; K264-W266 HydrophobicContact CD-CZ3 4.32Å; K264-W266 HydrophobicContact CG-CZ2 4.5Å
267N96.5Very high94.6Very high132 Ų132135 Ų13571%0.70666%0.657SS**SBendtrans-97.1141.3-176-65.6-26.6000111.5R265R265-N267 WeakPolarHBondContact CD-O 3.49Å; R265-N267 VanDerWaalsContact CG-O 3.28Å; R265-N267 WeakPolarHBondContact CG-O 3.32Å; R265-N267 PolarHBondContact NE-O 3.37Å
268R94.8Very high94.9Very high189 Ų189134.3 Ų134.371%0.71365%0.647SS**PPolyproline II helixtrans-55140.6175.8-171.9179.5169.7166.24.5111.8
269A94.5Very high95.2Very high50 Ų50132.5 Ų132.541%0.41363%0.628SS.*PPolyproline II helixtrans-65.1138.7171.100000112.1R265 L271R265-A269 VanDerWaalsContact CZ-CA 3.47Å; R265-A269 VanDerWaalsContact NH2-CA 3.32Å; A269-L271 PolarHBondContact O-N 3.46Å
270K96.5Very high95.5Very high200 Ų200128 Ų12887%0.8762%0.615SS**PPolyproline II helixtrans-60.3128.2167.5-73.3-174.3-179.91780107.5S272K270-S272 PolarHBondContact O-N 3.23Å
271L96.9Very high95.9Very high54 Ų54122.5 Ų122.528%0.28359%0.594SS.*PPolyproline II helixtrans-62.2137.1177.7-70.3168.8000110A269 Q275 R276A269-L271 PolarHBondContact O-N 3.46Å; L271-Q275 HydrophobicContact CB-CB 4.42Å; L271-Q275 HydrophobicContact CD2-CB 4.15Å; L271-R276 HydrophobicContact CB-CG 3.83Å; L271-R276 HydrophobicContact CD1-CG 4.31Å; L271-R276 PolarHBondContact O-NE 3.12Å
272S98.1Very high96.2Very high54 Ų54123.9 Ų123.938%0.37859%0.593SS.*PPolyproline II helixtrans-64.7165172.680.50000110.7K270 A274 Q275 R276K270-S272 PolarHBondContact O-N 3.23Å; S272-A274 VanDerWaalsContact C-N 3.33Å; S272-Q275 WeakPolarHBondContact OG-CB 3.38Å; S272-Q275 VanDerWaalsContact OG-CG 3.3Å; S272-Q275 WeakPolarHBondContact OG-CG 3.46Å; S272-Q275 PolarHBondContact OG-N 3.44Å; S272-Q275 VanDerWaalsContact OG-N 3.1Å; S272-R276 WeakPolarHBondContact O-CG 3.45Å; S272-R276 PolarHBondContact O-N 3.37Å; S272-R276 VanDerWaalsContact O-N 3.11Å; S272-R276 PolarHBondContact O-NE 2.89Å
273L97.9Very high96.5Very high105 Ų105123.6 Ų123.655%0.5558%0.581SS.*Hα-helixtrans-61.6-43.5174.4-178.961.7000111.3R276 K277L273-R276 PolarHBondContact O-N 3.06Å; L273-K277 PolarHBondContact O-N 3.2Å
274A98.1Very high96.8Very high55 Ų55120.1 Ų120.146%0.45557%0.566SS.*Hα-helixtrans-60.7-46.7178.100000111.8S272 R276 K277 N278S272-A274 VanDerWaalsContact C-N 3.33Å; A274-R276 VanDerWaalsContact C-N 3.28Å; A274-R276 PolarHBondContact O-N 3.49Å; A274-K277 PolarHBondContact O-N 3.02Å; A274-N278 WeakPolarHBondContact O-CB 3.47Å; A274-N278 VanDerWaalsContact O-CG 3.29Å; A274-N278 PolarHBondContact O-N 2.97Å
275Q98.1Very high97Very high105 Ų105115.5 Ų115.549%0.49155%0.554SS.*Hα-helixtrans-59.3-39.5176.1-73.3172.2-25.900112.1L271 S272 R279L271-Q275 HydrophobicContact CB-CB 4.42Å; L271-Q275 HydrophobicContact CD2-CB 4.15Å; S272-Q275 WeakPolarHBondContact OG-CB 3.38Å; S272-Q275 VanDerWaalsContact OG-CG 3.3Å; S272-Q275 WeakPolarHBondContact OG-CG 3.46Å; S272-Q275 PolarHBondContact OG-N 3.44Å; S272-Q275 VanDerWaalsContact OG-N 3.1Å; Q275-R279 VanDerWaalsContact O-CB 3.24Å; Q275-R279 WeakPolarHBondContact O-CB 3.48Å; Q275-R279 PolarHBondContact O-N 3.2Å
276R98.1Very high97.3Very high138 Ų138109.9 Ų109.952%0.52154%0.541SS..Hα-helixtrans-66.5-45.2176.5-74.6-179.2-77.1166.5-1.7112.2L271 S272 L273 A274 R279 V280L271-R276 HydrophobicContact CB-CG 3.83Å; L271-R276 HydrophobicContact CD1-CG 4.31Å; L271-R276 PolarHBondContact O-NE 3.12Å; S272-R276 WeakPolarHBondContact O-CG 3.45Å; S272-R276 PolarHBondContact O-N 3.37Å; S272-R276 VanDerWaalsContact O-N 3.11Å; S272-R276 PolarHBondContact O-NE 2.89Å; L273-R276 PolarHBondContact O-N 3.06Å; A274-R276 VanDerWaalsContact C-N 3.28Å; A274-R276 PolarHBondContact O-N 3.49Å; R276-R279 PolarHBondContact O-N 3.32Å; R276-V280 WeakPolarHBondContact O-CG2 3.36Å; R276-V280 PolarHBondContact O-N 3.22Å
277K98.1Very high97.4Very high138 Ų138105.7 Ų105.760%0.653%0.529SS*.Hα-helixtrans-62.2-49.3177.5-73.4-175.5175.5-173.80111.4L273 A274 R279 V280 A281L273-K277 PolarHBondContact O-N 3.2Å; A274-K277 PolarHBondContact O-N 3.02Å; K277-R279 VanDerWaalsContact C-N 3.3Å; K277-R279 PolarHBondContact O-N 3.47Å; K277-V280 WeakPolarHBondContact O-CB 3.03Å; K277-V280 PolarHBondContact O-N 3.39Å; K277-V280 VanDerWaalsContact O-N 3.08Å; K277-A281 PolarHBondContact O-N 2.96Å
278N98.1Very high97.4Very high99 Ų99103.9 Ų103.953%0.52952%0.519SS..Hα-helixtrans-61.8-40.2179.8-68.9-3.7000111.4A274 V280 A281 Q282A274-N278 WeakPolarHBondContact O-CB 3.47Å; A274-N278 VanDerWaalsContact O-CG 3.29Å; A274-N278 PolarHBondContact O-N 2.97Å; N278-V280 VanDerWaalsContact C-N 3.29Å; N278-V280 PolarHBondContact O-N 3.06Å; N278-A281 PolarHBondContact O-N 3.15Å; N278-Q282 WeakPolarHBondContact O-CB 3.35Å; N278-Q282 VanDerWaalsContact O-CG 3.32Å; N278-Q282 WeakPolarHBondContact O-CG 3.41Å; N278-Q282 PolarHBondContact O-N 3.49Å
279R97.8Very high97.5Very high126 Ų126102.3 Ų102.348%0.47551%0.513SS..Hα-helixtrans-59.8-38.4175.1-173.6179.4-173.1-162.2-0.1112.7Q275 R276 K277 K283Q275-R279 VanDerWaalsContact O-CB 3.24Å; Q275-R279 WeakPolarHBondContact O-CB 3.48Å; Q275-R279 PolarHBondContact O-N 3.2Å; R276-R279 PolarHBondContact O-N 3.32Å; K277-R279 VanDerWaalsContact C-N 3.3Å; K277-R279 PolarHBondContact O-N 3.47Å; R279-K283 WeakPolarHBondContact O-CB 3.34Å; R279-K283 WeakPolarHBondContact O-CG 3.43Å; R279-K283 PolarHBondContact O-N 3.38Å; R279-K283 VanDerWaalsContact O-N 3.12Å
280V98.1Very high97.5Very high85 Ų85101.8 Ų101.852%0.51551%0.509SS..Hα-helixtrans-67.4-45176.2172.20000110.5R276 K277 N278 K283 K284R276-V280 WeakPolarHBondContact O-CG2 3.36Å; R276-V280 PolarHBondContact O-N 3.22Å; K277-V280 WeakPolarHBondContact O-CB 3.03Å; K277-V280 PolarHBondContact O-N 3.39Å; K277-V280 VanDerWaalsContact O-N 3.08Å; N278-V280 VanDerWaalsContact C-N 3.29Å; N278-V280 PolarHBondContact O-N 3.06Å; V280-K283 PolarHBondContact O-N 3.24Å; V280-K284 PolarHBondContact O-N 3.15Å
281A97.8Very high97.4Very high59 Ų5996.9 Ų96.949%0.48849%0.489SS..Hα-helixtrans-60.1-48177.600000111.8K277 N278 K283 K284 A285K277-A281 PolarHBondContact O-N 2.96Å; N278-A281 PolarHBondContact O-N 3.15Å; A281-K283 VanDerWaalsContact C-N 3.32Å; A281-K283 PolarHBondContact O-N 3.35Å; A281-K284 PolarHBondContact O-N 3.17Å; A281-A285 PolarHBondContact O-N 3.44Å
282Q98Very high97.2Very high137 Ų137100.7 Ų100.764%0.6451%0.505SS*.Hα-helixtrans-58.5-42177-73.7173.8-16.100112.3N278 A285 S286N278-Q282 WeakPolarHBondContact O-CB 3.35Å; N278-Q282 VanDerWaalsContact O-CG 3.32Å; N278-Q282 WeakPolarHBondContact O-CG 3.41Å; N278-Q282 PolarHBondContact O-N 3.49Å; Q282-A285 PolarHBondContact O-N 3.11Å; Q282-S286 WeakPolarHBondContact O-CB 3.47Å; Q282-S286 PolarHBondContact O-N 3.2Å; Q282-S286 PolarHBondContact O-OG 3.39Å
283K98.1Very high96.9Very high129 Ų129104.5 Ų104.556%0.56152%0.517SS*.Hα-helixtrans-65.4-39177-80.6-171.1168.3-151.20113.4R279 V280 A281 S286 F287R279-K283 WeakPolarHBondContact O-CB 3.34Å; R279-K283 WeakPolarHBondContact O-CG 3.43Å; R279-K283 PolarHBondContact O-N 3.38Å; R279-K283 VanDerWaalsContact O-N 3.12Å; V280-K283 PolarHBondContact O-N 3.24Å; A281-K283 VanDerWaalsContact C-N 3.32Å; A281-K283 PolarHBondContact O-N 3.35Å; K283-S286 WeakPolarHBondContact CA-OG 3.4Å; K283-S286 PolarHBondContact O-OG 3.15Å; K283-F287 WeakPolarHBondContact O-CB 3.44Å; K283-F287 PolarHBondContact O-N 3.37Å; K283-F287 VanDerWaalsContact O-N 3.15Å
284K97.7Very high96.5Very high143 Ų143106.8 Ų106.862%0.62253%0.525SS*.Hα-helixtrans-64.8-47.9175.1-72.5-176.9174.8-1690110.6V280 A281 S286 F287 L288V280-K284 PolarHBondContact O-N 3.15Å; A281-K284 PolarHBondContact O-N 3.17Å; K284-S286 PolarHBondContact O-N 3.07Å; K284-F287 PolarHBondContact O-N 3.39Å; K284-L288 WeakPolarHBondContact O-CG 3.28Å; K284-L288 PolarHBondContact O-N 3.31Å
285A97.6Very high95.8Very high48 Ų48107.9 Ų107.940%0.39753%0.534SS..Hα-helixtrans-64.5-37.8179.600000112.9A281 Q282 R289A281-A285 PolarHBondContact O-N 3.44Å; Q282-A285 PolarHBondContact O-N 3.11Å; A285-R289 WeakPolarHBondContact O-CG 3.37Å; A285-R289 PolarHBondContact O-N 2.82Å; A285-R289 PolarHBondContact O-NE 3.17Å
286S97.4Very high94.7Very high54 Ų54105.7 Ų105.738%0.37854%0.54SS..Hα-helixtrans-67-36.9174.862.70000112.7Q282 K283 K284 A290Q282-S286 WeakPolarHBondContact O-CB 3.47Å; Q282-S286 PolarHBondContact O-N 3.2Å; Q282-S286 PolarHBondContact O-OG 3.39Å; K283-S286 WeakPolarHBondContact CA-OG 3.4Å; K283-S286 PolarHBondContact O-OG 3.15Å; K284-S286 PolarHBondContact O-N 3.07Å; S286-A290 PolarHBondContact O-N 3.49Å; S286-A290 VanDerWaalsContact O-N 3.15Å
287F97.2Very high92.8Very high120 Ų120106.6 Ų106.653%0.52656%0.555SS.*Hα-helixtrans-68-46.2179.2179.2-97.9000111.9K283 K284 R289 A290 Q291K283-F287 WeakPolarHBondContact O-CB 3.44Å; K283-F287 PolarHBondContact O-N 3.37Å; K283-F287 VanDerWaalsContact O-N 3.15Å; K284-F287 PolarHBondContact O-N 3.39Å; F287-R289 VanDerWaalsContact C-N 3.34Å; F287-R289 PolarHBondContact O-N 3.5Å; F287-A290 PolarHBondContact O-N 3Å; F287-Q291 HydrophobicContact CD1-CG 4.44Å; F287-Q291 HydrophobicContact CE1-CG 3.99Å; F287-Q291 HydrophobicContact CZ-CG 4.04Å; F287-Q291 PolarHBondContact O-N 3Å; F287-Q291 VanDerWaalsContact O-N 3.08Å
288L96.6Very high90.6Very high93 Ų93106 Ų10649%0.48759%0.587SS.*Hα-helixtrans-59.5-44.9177.1-68.8171.5000111.7K284 A290 Q291 E292K284-L288 WeakPolarHBondContact O-CG 3.28Å; K284-L288 PolarHBondContact O-N 3.31Å; L288-A290 VanDerWaalsContact C-N 3.31Å; L288-A290 PolarHBondContact O-N 3.01Å; L288-Q291 PolarHBondContact O-N 3.21Å; L288-E292 WeakPolarHBondContact O-CG 3.41Å; L288-E292 PolarHBondContact O-N 3.08Å
289R96.3Very high90.2Very high156 Ų156106.3 Ų106.359%0.58959%0.59SS**Hα-helixtrans-59.6-38.5175.4-74.3-174.3-64.4162.32.4113.3A285 F287 E292 Q293A285-R289 WeakPolarHBondContact O-CG 3.37Å; A285-R289 PolarHBondContact O-N 2.82Å; A285-R289 PolarHBondContact O-NE 3.17Å; F287-R289 VanDerWaalsContact C-N 3.34Å; F287-R289 PolarHBondContact O-N 3.5Å; R289-E292 PolarHBondContact O-N 3.36Å; R289-Q293 WeakPolarHBondContact O-CG 3.31Å; R289-Q293 PolarHBondContact O-N 3.16Å; R289-Q293 VanDerWaalsContact O-N 3.11Å
290A95.3Very high89.9Confident40 Ų40105.3 Ų105.333%0.33160%0.596SS.*Hα-helixtrans-67.5-40.2177.900000111.8S286 F287 L288 Q293 E294S286-A290 PolarHBondContact O-N 3.49Å; S286-A290 VanDerWaalsContact O-N 3.15Å; F287-A290 PolarHBondContact O-N 3Å; L288-A290 VanDerWaalsContact C-N 3.31Å; L288-A290 PolarHBondContact O-N 3.01Å; A290-Q293 PolarHBondContact O-N 3.27Å; A290-E294 PolarHBondContact O-N 3.13Å
291Q95.1Very high89.4Confident96 Ų96106.4 Ų106.445%0.44960%0.601SS.*Hα-helixtrans-65.2-39.8175.3-69.2-166.3-50.200112.5F287 L288 Q293 E294 A295F287-Q291 HydrophobicContact CD1-CG 4.44Å; F287-Q291 HydrophobicContact CE1-CG 3.99Å; F287-Q291 HydrophobicContact CZ-CG 4.04Å; F287-Q291 PolarHBondContact O-N 3Å; F287-Q291 VanDerWaalsContact O-N 3.08Å; L288-Q291 PolarHBondContact O-N 3.21Å; Q291-Q293 VanDerWaalsContact C-N 3.31Å; Q291-Q293 PolarHBondContact O-N 3.29Å; Q291-E294 PolarHBondContact O-N 3.29Å; Q291-A295 VanDerWaalsContact O-CB 3.31Å; Q291-A295 WeakPolarHBondContact O-CB 3.45Å; Q291-A295 PolarHBondContact O-N 3.14Å
292E93.1Very high88.9Confident134 Ų134109.2 Ų109.263%0.62661%0.607SS**Hα-helixtrans-64.1-37176.5-73167.5-178.600111.9L288 R289 G296L288-E292 WeakPolarHBondContact O-CG 3.41Å; L288-E292 PolarHBondContact O-N 3.08Å; R289-E292 PolarHBondContact O-N 3.36Å; E292-G296 PolarHBondContact O-N 3.07Å; E292-G296 VanDerWaalsContact O-N 3.16Å
293Q90.7Very high88.3Confident134 Ų134107.4 Ų107.463%0.62661%0.605SS**Hα-helixtrans-69.9-46.6175.6-74.3176.7-27.100112.1R289 A290 Q291 A295 G296 D297R289-Q293 WeakPolarHBondContact O-CG 3.31Å; R289-Q293 PolarHBondContact O-N 3.16Å; R289-Q293 VanDerWaalsContact O-N 3.11Å; A290-Q293 PolarHBondContact O-N 3.27Å; Q291-Q293 VanDerWaalsContact C-N 3.31Å; Q291-Q293 PolarHBondContact O-N 3.29Å; Q293-A295 PolarHBondContact O-N 3.14Å; Q293-G296 PolarHBondContact O-N 3.3Å; Q293-D297 PolarHBondContact O-N 3.48Å; Q293-D297 VanDerWaalsContact O-N 3.14Å
294E89.1Confident87.7Confident154 Ų154106 Ų10672%0.7261%0.608SS**Hα-helixtrans-61.4-32.1176.2-75.7177.8175.600112.7A290 Q291A290-E294 PolarHBondContact O-N 3.13Å; Q291-E294 PolarHBondContact O-N 3.29Å
295A84.1Confident87Confident78 Ų78103.4 Ų103.465%0.64561%0.607SS**Hα-helixtrans-79.9-17176.300000113.8Q291 Q293Q291-A295 VanDerWaalsContact O-CB 3.31Å; Q291-A295 WeakPolarHBondContact O-CB 3.45Å; Q291-A295 PolarHBondContact O-N 3.14Å; Q293-A295 PolarHBondContact O-N 3.14Å
296G74.1Confident86.2Confident59 Ų59107.6 Ų107.661%0.60862%0.624SS**Hα-helixtrans-94-20.2178.500000114.5E292 Q293E292-G296 PolarHBondContact O-N 3.07Å; E292-G296 VanDerWaalsContact O-N 3.16Å; Q293-G296 PolarHBondContact O-N 3.3Å
297D59.6Low85.2Confident156 Ų156112.1 Ų112.183%0.83464%0.644SS**  trans-95.27.5179.3-76.4-22.7000113.7Q293Q293-D297 PolarHBondContact O-N 3.48Å; Q293-D297 VanDerWaalsContact O-N 3.14Å
298G51.6Low84.1Confident125 Ų125111.4 Ų111.4100%1.28966%0.655SS**  trans-119.70176.200000112.7

Retrieved 298 of 298 residues in 144.1 ms (Link to these results)