A0A087YHL9_POEFO Loading...

alpha-1,2-Mannosidase

AlphaFold DB , UniProt , Accession A0A087YHL9, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 887 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40.9Very low37.7Very low240 Ų240128.2 Ų128.2100%1.18269%0.693SS**  0151.30-59-172.6-151.800107.8
2P40.5Very low37.1Very low103 Ų103123.3 Ų123.367%0.66970%0.695SS**  trans-78.8155.7-164.731.7-36.4000113.9V4P2-V4 HydrophobicContact CB-CG2 4.21Å; P2-V4 HydrophobicContact CG-CG2 4.25Å; P2-V4 PolarHBondContact O-N 3.37Å
3P41Very low36.7Very low107 Ų107120.2 Ų120.270%0.69569%0.694SS**THydrogen-bonded Turntrans-80.132.5-17135.4-38.9000114.6
4V41.7Very low36.4Very low95 Ų95120.7 Ų120.758%0.57669%0.692SS**Hα-helixtrans-72.9-33.2-172.5-177.20000112.4P2 C6P2-V4 HydrophobicContact CB-CG2 4.21Å; P2-V4 HydrophobicContact CG-CG2 4.25Å; P2-V4 PolarHBondContact O-N 3.37Å; V4-C6 PolarHBondContact O-N 2.99Å
5L40Very low36.2Very low140 Ų140126.7 Ų126.773%0.73370%0.699SS**Hα-helixtrans-72.6-26.7-172-141.974.2000113.9
6C36.8Very low35.9Very low87 Ų87125.5 Ų125.559%0.58870%0.702SS**Hα-helixtrans-77.9-27.7-178.3-62.90000113.5V4 L10V4-C6 PolarHBondContact O-N 2.99Å; C6-L10 PolarHBondContact O-N 2.85Å
7L37.5Very low36.3Very low109 Ų109128.7 Ų128.757%0.57170%0.703SS**Hα-helixtrans-68.8-38.2176.7-9884000112M9 L10 F11L7-M9 VanDerWaalsContact C-N 3.33Å; L7-M9 PolarHBondContact O-N 2.94Å; L7-L10 PolarHBondContact O-N 2.91Å; L7-F11 PolarHBondContact O-N 3.45Å
8L35.8Very low36.8Very low128 Ų128124.8 Ų124.867%0.6770%0.697SS**Hα-helixtrans-66.1-35179.4-73.6165.6000112.4G12L8-G12 PolarHBondContact O-N 3.22Å
9M34Very low37.8Very low153 Ų153128 Ų12875%0.75471%0.706SS**Hα-helixtrans-66.4-34.4172.2-73.9-72.8-159.300112.9L7L7-M9 VanDerWaalsContact C-N 3.33Å; L7-M9 PolarHBondContact O-N 2.94Å
10L34Very low39.5Very low111 Ų111125.1 Ų125.158%0.58170%0.7SS**Hα-helixtrans-78-33.2-178.9-81.9163.7000113.2C6 L7 G12 A13C6-L10 PolarHBondContact O-N 2.85Å; L7-L10 PolarHBondContact O-N 2.91Å; L10-G12 VanDerWaalsContact C-N 3.32Å; L10-A13 PolarHBondContact O-N 2.76Å
11F32.3Very low41.8Very low137 Ų137120.1 Ų120.160%0.60167%0.671SS**Hα-helixtrans-66.7-33.6171.5-92.6-86.3000112.5L7 A13L7-F11 PolarHBondContact O-N 3.45Å; F11-A13 PolarHBondContact O-N 2.03Å
12G31.3Very low44.2Very low70 Ų70110.6 Ų110.672%0.72263%0.628SS**THydrogen-bonded Turntrans-70.5-5.6176.700000115.8L8 L10L8-G12 PolarHBondContact O-N 3.22Å; L10-G12 VanDerWaalsContact C-N 3.32Å
13A31.3Very low46.5Very low82 Ų82111 Ų11168%0.67862%0.616SS**THydrogen-bonded Turntrans-119.41-174.800000114.5L10 F11L10-A13 PolarHBondContact O-N 2.76Å; F11-A13 PolarHBondContact O-N 2.03Å
14L32.7Very low49Very low128 Ų128112.1 Ų112.167%0.6761%0.613SS**THydrogen-bonded Turntrans-112.6-10.5-178.4-84.3164.3000114.2
15W33.5Very low51.5Low210 Ų210111.5 Ų111.580%0.79560%0.603SS**  trans-104.779.4176-75.34.5000111.3
16S31.8Very low54.1Low108 Ų108105.3 Ų105.376%0.75557%0.57SS**  trans-124.448.8150.8-167.60000108.9
17Y42.2Very low56.8Low180 Ų180104.1 Ų104.171%0.70656%0.556SS**PPolyproline II helixtrans-59.9132.2147.6-67.7-89.3000105.8E19Y17-E19 PolarHBondContact O-N 3.49Å
18G45Very low59.7Low59 Ų59104.9 Ų104.961%0.60856%0.555SS**PPolyproline II helixtrans-62.6123.4161.700000106.1A20G18-A20 PolarHBondContact O-N 3.42Å; G18-A20 VanDerWaalsContact O-N 3.17Å
19E56.3Low62.6Low185 Ų18599 Ų9986%0.86452%0.524SS*.PPolyproline II helixtrans-59.1123.2179-74.1179.7114.700108.1Y17 M21Y17-E19 PolarHBondContact O-N 3.49Å; E19-M21 PolarHBondContact O-N 2.92Å
20A71.7Confident65.6Low70 Ų7093.3 Ų93.358%0.57949%0.494SS*.PPolyproline II helixtrans-67.3120.9172.700000107G18 S22 P397G18-A20 PolarHBondContact O-N 3.42Å; G18-A20 VanDerWaalsContact O-N 3.17Å; A20-S22 PolarHBondContact O-N 3.31Å; A20-P397 HydrophobicContact CB-CB 4.1Å; A20-P397 HydrophobicContact CB-CG 4.09Å
21M88.1Confident68.6Low20 Ų2092 Ų9210%0.09949%0.488CS..  trans-41.5125.5179.3-177.2-179-68.300110.7E19 E25 K26 F29 L400 R404 F451E19-M21 PolarHBondContact O-N 2.92Å; M21-E25 HydrophobicContact CG-CB 3.5Å; M21-E25 HydrophobicContact SD-CB 4.46Å; M21-K26 HydrophobicContact CG-CG 4.15Å; M21-K26 HydrophobicContact SD-CG 3.89Å; M21-F29 HydrophobicContact CE-CD2 3.86Å; M21-F29 HydrophobicContact CE-CE2 3.68Å; M21-F29 HydrophobicContact SD-CD2 3.56Å; M21-F29 VanDerWaalsContact SD-CD2 3.56Å; M21-F29 HydrophobicContact SD-CE2 3.86Å; M21-L400 HydrophobicContact CB-CD1 4.02Å; M21-L400 HydrophobicContact CE-CB 3.8Å; M21-L400 HydrophobicContact SD-CB 4.01Å; M21-L400 HydrophobicContact SD-CD1 4.36Å; M21-R404 HydrophobicContact CE-CB 4.4Å; M21-F451 HydrophobicContact CE-CE1 4.06Å; M21-F451 HydrophobicContact SD-CD1 4.09Å; M21-F451 HydrophobicContact SD-CE1 3.78Å
22S90.7Very high71.8Confident40 Ų4087.5 Ų87.528%0.2847%0.468SS..  trans-66.6161.8-173.3102.30000111.3A20 E24 E25 K26A20-S22 PolarHBondContact O-N 3.31Å; S22-E24 VanDerWaalsContact CB-OE2 3.31Å; S22-E24 WeakPolarHBondContact CB-OE2 3.05Å; S22-E24 PolarHBondContact O-N 3.05Å; S22-E24 PolarHBondContact OG-N 3.01Å; S22-E24 PolarHBondContact OG-OE2 2.7Å; S22-E25 PolarHBondContact N-OE2 2.67Å; S22-E25 PolarHBondContact O-N 2.75Å; S22-E25 VanDerWaalsContact O-N 3.08Å; S22-E25 PolarHBondContact OG-N 3.29Å; S22-E25 VanDerWaalsContact OG-N 3.15Å; S22-K26 PolarHBondContact O-N 2.96Å
23R89.8Confident75Confident112 Ų11284.1 Ų84.142%0.42343%0.434SS..Hα-helixtrans-60.3-38.2175.7-167.1-178.4-171.5175.78.1110.8E25 K26 Q27 E453 E455R23-E25 VanDerWaalsContact C-N 3.34Å; R23-K26 PolarHBondContact O-N 3.07Å; R23-Q27 WeakPolarHBondContact O-CB 3.39Å; R23-Q27 WeakPolarHBondContact O-CG 3.45Å; R23-Q27 PolarHBondContact O-N 2.74Å; R23-E453 HydrophobicContact CG-CG 4.25Å; R23-E455 IonicContact CZ-OE1 3.51Å; R23-E455 IonicContact CZ-OE2 2.67Å; R23-E455 IonicContact NH1-OE1 2.78Å; R23-E455 IonicContact NH2-OE1 2.67Å; R23-E455 PolarHBondContact NH2-OE1 2.95Å; R23-E455 IonicContact NH2-OE2 3.56Å; R23-E455 PolarHBondContact NH2-OE2 2.86Å
24E92.6Very high78.2Confident131 Ų13181.7 Ų81.761%0.61241%0.41SS*.Hα-helixtrans-65.2-36.1175.5-55.174.8-165.800111.9S22 K28S22-E24 VanDerWaalsContact CB-OE2 3.31Å; S22-E24 WeakPolarHBondContact CB-OE2 3.05Å; S22-E24 PolarHBondContact O-N 3.05Å; S22-E24 PolarHBondContact OG-N 3.01Å; S22-E24 PolarHBondContact OG-OE2 2.7Å; E24-K28 WeakPolarHBondContact O-CB 3.03Å; E24-K28 PolarHBondContact O-N 2.81Å
25E93.8Very high81.3Confident81 Ų8179.8 Ų79.838%0.37940%0.398SS..Hα-helixtrans-71-45.5173.2-67.8-175.9117.800112.3M21 S22 R23 Q27 K28 F29M21-E25 HydrophobicContact CG-CB 3.5Å; M21-E25 HydrophobicContact SD-CB 4.46Å; S22-E25 PolarHBondContact N-OE2 2.67Å; S22-E25 PolarHBondContact O-N 2.75Å; S22-E25 VanDerWaalsContact O-N 3.08Å; S22-E25 PolarHBondContact OG-N 3.29Å; S22-E25 VanDerWaalsContact OG-N 3.15Å; R23-E25 VanDerWaalsContact C-N 3.34Å; E25-Q27 VanDerWaalsContact C-N 3.35Å; E25-Q27 PolarHBondContact O-N 3.14Å; E25-K28 WeakPolarHBondContact O-CB 3.47Å; E25-K28 PolarHBondContact O-N 3.19Å; E25-K28 VanDerWaalsContact O-N 3.14Å; E25-F29 HydrophobicContact CB-CE2 4.41Å; E25-F29 WeakPolarHBondContact O-CD2 3.07Å; E25-F29 PolarHBondContact O-N 3.28Å
26K94.4Very high84.4Confident10 Ų1069.8 Ų69.84%0.04336%0.36CS..Hα-helixtrans-54.8-50.2171.7-85.4-168.267.3-164.20110.9M21 S22 R23 K28 F29 R30 L400 F451 A452 E453M21-K26 HydrophobicContact CG-CG 4.15Å; M21-K26 HydrophobicContact SD-CG 3.89Å; S22-K26 PolarHBondContact O-N 2.96Å; R23-K26 PolarHBondContact O-N 3.07Å; K26-K28 VanDerWaalsContact C-N 3.3Å; K26-K28 PolarHBondContact O-N 2.57Å; K26-F29 PolarHBondContact O-N 2.88Å; K26-F29 VanDerWaalsContact O-N 3.16Å; K26-R30 WeakPolarHBondContact O-CB 3.38Å; K26-R30 PolarHBondContact O-N 2.85Å; K26-L400 HydrophobicContact CD-CD1 4Å; K26-L400 HydrophobicContact CD-CD2 4.43Å; K26-L400 HydrophobicContact CG-CD1 4.18Å; K26-F451 VanDerWaalsContact CE-O 3.24Å; K26-F451 WeakPolarHBondContact CE-O 3.4Å; K26-F451 HydrophobicContact CG-CD1 4.48Å; K26-A452 PolarHBondContact NZ-O 2.9Å; K26-E453 WeakPolarHBondContact CD-OE1 3.46Å; K26-E453 VanDerWaalsContact CE-OE1 3.29Å; K26-E453 WeakPolarHBondContact CE-OE1 3.28Å; K26-E453 IonicContact NZ-OE1 3.49Å; K26-E453 PolarHBondContact NZ-OE1 2.88Å; K26-E453 IonicContact NZ-OE2 2.83Å; K26-E453 PolarHBondContact NZ-OE2 2.83Å
27Q95Very high87.6Confident63 Ų6364.6 Ų64.629%0.29432%0.324SS..Hα-helixtrans-60.3-36.9176.7-73.2-178.9-17.200112.7R23 E25 N31R23-Q27 WeakPolarHBondContact O-CB 3.39Å; R23-Q27 WeakPolarHBondContact O-CG 3.45Å; R23-Q27 PolarHBondContact O-N 2.74Å; E25-Q27 VanDerWaalsContact C-N 3.35Å; E25-Q27 PolarHBondContact O-N 3.14Å; Q27-N31 WeakPolarHBondContact O-CB 3.36Å; Q27-N31 PolarHBondContact O-N 3.47Å; Q27-N31 PolarHBondContact O-ND2 2.91Å
28K96.8Very high90.3Very high124 Ų12459 Ų5954%0.53931%0.306SS..Hα-helixtrans-63.3-48.8173.1-179.8-160.7168.2-154.20111.3E24 E25 K26 N31 Q32E24-K28 WeakPolarHBondContact O-CB 3.03Å; E24-K28 PolarHBondContact O-N 2.81Å; E25-K28 WeakPolarHBondContact O-CB 3.47Å; E25-K28 PolarHBondContact O-N 3.19Å; E25-K28 VanDerWaalsContact O-N 3.14Å; K26-K28 VanDerWaalsContact C-N 3.3Å; K26-K28 PolarHBondContact O-N 2.57Å; K28-N31 PolarHBondContact O-N 2.89Å; K28-Q32 PolarHBondContact O-N 3.19Å
29F97.5Very high92.8Very high4 Ų457.9 Ų57.92%0.01829%0.285CS..Hα-helixtrans-66.9-41.4179-69.1-62.3000111.8M21 E25 K26 N31 Q32 V33 R404 L407 F451M21-F29 HydrophobicContact CE-CD2 3.86Å; M21-F29 HydrophobicContact CE-CE2 3.68Å; M21-F29 HydrophobicContact SD-CD2 3.56Å; M21-F29 VanDerWaalsContact SD-CD2 3.56Å; M21-F29 HydrophobicContact SD-CE2 3.86Å; E25-F29 HydrophobicContact CB-CE2 4.41Å; E25-F29 WeakPolarHBondContact O-CD2 3.07Å; E25-F29 PolarHBondContact O-N 3.28Å; K26-F29 PolarHBondContact O-N 2.88Å; K26-F29 VanDerWaalsContact O-N 3.16Å; F29-N31 VanDerWaalsContact C-N 3.34Å; F29-N31 PolarHBondContact O-N 3.32Å; F29-Q32 CarbonylContact O-C 3.57Å; F29-Q32 WeakPolarHBondContact O-CA 3.37Å; F29-Q32 WeakPolarHBondContact O-CB 3.34Å; F29-Q32 PolarHBondContact O-N 3.18Å; F29-V33 WeakPolarHBondContact O-CG2 3.4Å; F29-V33 PolarHBondContact O-N 3.01Å; F29-R404 HydrophobicContact CE1-CG 3.82Å; F29-R404 HydrophobicContact CE2-CG 4.38Å; F29-R404 HydrophobicContact CZ-CG 3.73Å; F29-L407 HydrophobicContact CB-CD1 4.05Å; F29-L407 HydrophobicContact CD1-CD1 4.17Å; F29-L407 HydrophobicContact CG-CD1 4.47Å; F29-F451 HydrophobicContact CB-CB 4.4Å; F29-F451 HydrophobicContact CB-CD1 3.79Å; F29-F451 HydrophobicContact CB-CD2 4.02Å; F29-F451 HydrophobicContact CB-CE1 4.05Å; F29-F451 HydrophobicContact CB-CE2 4.28Å; F29-F451 HydrophobicContact CB-CG 3.79Å; F29-F451 HydrophobicContact CB-CZ 4.3Å; F29-F451 HydrophobicContact CD2-CE1 4.35Å; F29-F451 HydrophobicContact CG-CE1 4.4Å
30R97Very high94.8Very high35 Ų3549 Ų4913%0.13224%0.244CC..Hα-helixtrans-54.3-47.2170.6-173.6-152.970.6-159.510.9111.9K26 Q32 V33 V34 F448 F451 D456K26-R30 WeakPolarHBondContact O-CB 3.38Å; K26-R30 PolarHBondContact O-N 2.85Å; R30-Q32 VanDerWaalsContact C-N 3.3Å; R30-Q32 PolarHBondContact O-N 2.7Å; R30-V33 WeakPolarHBondContact O-CB 3.44Å; R30-V33 PolarHBondContact O-N 3.19Å; R30-V34 WeakPolarHBondContact O-CG2 3.32Å; R30-V34 PolarHBondContact O-N 3.22Å; R30-V34 VanDerWaalsContact O-N 3.13Å; R30-F448 HydrophobicContact CG-CD2 3.78Å; R30-F448 HydrophobicContact CG-CE2 3.65Å; R30-F451 HydrophobicContact CB-CB 3.85Å; R30-D456 WeakPolarHBondContact CD-OD2 3.49Å; R30-D456 IonicContact CZ-OD1 2.78Å; R30-D456 IonicContact CZ-OD2 3.56Å; R30-D456 IonicContact NE-OD2 2.66Å; R30-D456 IonicContact NH1-OD1 2.68Å; R30-D456 PolarHBondContact NH1-OD1 3.37Å; R30-D456 IonicContact NH1-OD2 3.64Å; R30-D456 PolarHBondContact NH1-OD2 3.3Å
31N97.7Very high96.1Very high84 Ų8445.9 Ų45.945%0.44922%0.217SC..Hα-helixtrans-65.6-32.3176-69.2-19.7000112.5Q27 K28 F29 V34 E35Q27-N31 WeakPolarHBondContact O-CB 3.36Å; Q27-N31 PolarHBondContact O-N 3.47Å; Q27-N31 PolarHBondContact O-ND2 2.91Å; K28-N31 PolarHBondContact O-N 2.89Å; F29-N31 VanDerWaalsContact C-N 3.34Å; F29-N31 PolarHBondContact O-N 3.32Å; N31-V34 PolarHBondContact O-N 3.23Å; N31-E35 PolarHBondContact O-N 2.77Å
32Q98.1Very high96.6Very high41 Ų4149.3 Ų49.319%0.19223%0.233CC..Hα-helixtrans-68.2-36.8172.5-173.7177.3-18.900111.6K28 F29 R30 E35 M36 N411K28-Q32 PolarHBondContact O-N 3.19Å; F29-Q32 CarbonylContact O-C 3.57Å; F29-Q32 WeakPolarHBondContact O-CA 3.37Å; F29-Q32 WeakPolarHBondContact O-CB 3.34Å; F29-Q32 PolarHBondContact O-N 3.18Å; R30-Q32 VanDerWaalsContact C-N 3.3Å; R30-Q32 PolarHBondContact O-N 2.7Å; Q32-E35 PolarHBondContact O-N 3.42Å; Q32-M36 HydrophobicContact CG-SD 4.28Å; Q32-M36 WeakPolarHBondContact O-CB 3.27Å; Q32-M36 WeakPolarHBondContact O-CG 3.06Å; Q32-M36 PolarHBondContact O-N 2.77Å; Q32-N411 PolarHBondContact NE2-ND2 2.71Å
33V98.4Very high96.9Very high0 Ų048.5 Ų48.50%023%0.225CC..Hα-helixtrans-58-48.6170.1-1770000110.7F29 R30 E35 M36 F37 L407 F444 L447 F448 F451F29-V33 WeakPolarHBondContact O-CG2 3.4Å; F29-V33 PolarHBondContact O-N 3.01Å; R30-V33 WeakPolarHBondContact O-CB 3.44Å; R30-V33 PolarHBondContact O-N 3.19Å; V33-E35 VanDerWaalsContact C-N 3.33Å; V33-E35 PolarHBondContact O-N 3.13Å; V33-M36 PolarHBondContact O-N 3.36Å; V33-F37 WeakPolarHBondContact O-CB 3.48Å; V33-F37 PolarHBondContact O-N 3.04Å; V33-L407 HydrophobicContact CG2-CD1 4.06Å; V33-L407 HydrophobicContact CG2-CD2 3.87Å; V33-F444 HydrophobicContact CG1-CB 4.21Å; V33-F444 HydrophobicContact CG1-CD1 3.97Å; V33-L447 HydrophobicContact CG1-CB 4.26Å; V33-L447 HydrophobicContact CG2-CB 4.04Å; V33-F448 HydrophobicContact CG1-CB 3.98Å; V33-F451 HydrophobicContact CG2-CD2 4.25Å
34V98.4Very high97.3Very high30 Ų3043.1 Ų43.118%0.18221%0.205CC..Hα-helixtrans-62.6-40.2179.3-177.30000111.5R30 N31 F37 D38 L94 F448R30-V34 WeakPolarHBondContact O-CG2 3.32Å; R30-V34 PolarHBondContact O-N 3.22Å; R30-V34 VanDerWaalsContact O-N 3.13Å; N31-V34 PolarHBondContact O-N 3.23Å; V34-F37 PolarHBondContact O-N 3.19Å; V34-D38 WeakPolarHBondContact O-CB 3.18Å; V34-D38 PolarHBondContact O-N 3.49Å; V34-L94 HydrophobicContact CG2-CD2 4.39Å; V34-F448 HydrophobicContact CG2-CD2 4.06Å; V34-F448 HydrophobicContact CG2-CE2 3.99Å
35E98.3Very high97.6Very high88 Ų8838 Ų3841%0.41118%0.181SC..Hα-helixtrans-65.3-40176.4-171.8-84.8155.300112.9N31 Q32 V33 D38 H39 R415N31-E35 PolarHBondContact O-N 2.77Å; Q32-E35 PolarHBondContact O-N 3.42Å; V33-E35 VanDerWaalsContact C-N 3.33Å; V33-E35 PolarHBondContact O-N 3.13Å; E35-D38 PolarHBondContact O-N 3.45Å; E35-H39 WeakPolarHBondContact O-CB 3.29Å; E35-H39 PolarHBondContact O-N 2.97Å; E35-R415 IonicContact OE1-CZ 3.44Å; E35-R415 IonicContact OE1-NH1 3.29Å; E35-R415 PolarHBondContact OE1-NH1 3.13Å; E35-R415 IonicContact OE1-NH2 2.7Å; E35-R415 PolarHBondContact OE1-NH2 3.39Å; E35-R415 IonicContact OE2-CZ 3.61Å; E35-R415 IonicContact OE2-NH1 2.75Å; E35-R415 PolarHBondContact OE2-NH1 3.07Å; E35-R415 IonicContact OE2-NH2 3.6Å
36M98.6Very high97.8Very high0 Ų039 Ų390%019%0.189CC..Hα-helixtrans-68.4-40.1175-66.4166.574.500112.1Q32 V33 H39 A40 L407 L410 N411 F420 F444Q32-M36 HydrophobicContact CG-SD 4.28Å; Q32-M36 WeakPolarHBondContact O-CB 3.27Å; Q32-M36 WeakPolarHBondContact O-CG 3.06Å; Q32-M36 PolarHBondContact O-N 2.77Å; V33-M36 PolarHBondContact O-N 3.36Å; M36-H39 PolarHBondContact O-N 3.44Å; M36-A40 WeakPolarHBondContact O-CB 3.42Å; M36-A40 PolarHBondContact O-N 3.08Å; M36-L407 HydrophobicContact CE-CD2 4.11Å; M36-L407 HydrophobicContact SD-CD2 3.58Å; M36-L407 VanDerWaalsContact SD-CD2 3.58Å; M36-L410 HydrophobicContact CE-CB 3.59Å; M36-L410 HydrophobicContact CE-CD1 4.03Å; M36-L410 HydrophobicContact CE-CG 4.47Å; M36-N411 WeakPolarHBondContact CE-ND2 3.49Å; M36-N411 PolarHBondContact SD-ND2 3.38Å; M36-F420 HydrophobicContact CB-CE2 4.17Å; M36-F420 HydrophobicContact CB-CZ 3.82Å; M36-F420 HydrophobicContact CE-CE1 3.68Å; M36-F420 HydrophobicContact CE-CZ 3.68Å; M36-F420 HydrophobicContact CG-CZ 3.92Å; M36-F444 HydrophobicContact CB-CD1 4.32Å; M36-F444 HydrophobicContact CB-CE1 3.39Å; M36-F444 HydrophobicContact CB-CZ 3.75Å; M36-F444 HydrophobicContact CE-CE1 3.91Å; M36-F444 HydrophobicContact CE-CZ 4.49Å; M36-F444 HydrophobicContact CG-CE1 4.44Å; M36-F444 HydrophobicContact SD-CE1 4.31Å
37F98.7Very high98Very high0 Ų042.3 Ų42.30%021%0.205CC..Hα-helixtrans-61.7-47.9173.6175.8-84.2000110.7V33 V34 H39 A40 Y41 T87 T90 L91 L94 K96 L440 F444V33-F37 WeakPolarHBondContact O-CB 3.48Å; V33-F37 PolarHBondContact O-N 3.04Å; V34-F37 PolarHBondContact O-N 3.19Å; F37-H39 VanDerWaalsContact C-N 3.32Å; F37-H39 PolarHBondContact O-N 2.79Å; F37-A40 PolarHBondContact O-N 2.96Å; F37-A40 VanDerWaalsContact O-N 3.1Å; F37-Y41 HydrophobicContact CE1-CG 4.09Å; F37-Y41 HydrophobicContact CZ-CD2 4.32Å; F37-Y41 HydrophobicContact CZ-CG 4.21Å; F37-Y41 WeakPolarHBondContact O-CB 3.44Å; F37-Y41 PolarHBondContact O-N 2.83Å; F37-T87 HydrophobicContact CE2-CG2 3.63Å; F37-T87 HydrophobicContact CZ-CG2 3.47Å; F37-T87 VanDerWaalsContact CZ-CG2 3.47Å; F37-T90 HydrophobicContact CD2-CG2 4.2Å; F37-T90 HydrophobicContact CE2-CG2 3.63Å; F37-T90 HydrophobicContact CZ-CG2 4.33Å; F37-L91 HydrophobicContact CE1-CD2 3.8Å; F37-L91 HydrophobicContact CZ-CD2 3.74Å; F37-L91 HydrophobicContact CZ-CG 4.45Å; F37-L94 HydrophobicContact CB-CD1 3.97Å; F37-L94 HydrophobicContact CD1-CD1 3.5Å; F37-L94 VanDerWaalsContact CD1-CD1 3.5Å; F37-L94 HydrophobicContact CD2-CD1 3.5Å; F37-L94 VanDerWaalsContact CD2-CD1 3.5Å; F37-L94 HydrophobicContact CE1-CD1 3.8Å; F37-L94 HydrophobicContact CE2-CD1 3.79Å; F37-L94 HydrophobicContact CG-CD1 3.34Å; F37-L94 HydrophobicContact CZ-CD1 3.93Å; F37-K96 HydrophobicContact CD1-CD 4.28Å; F37-K96 HydrophobicContact CE1-CD 3.94Å; F37-L440 HydrophobicContact CD2-CD2 4.11Å; F37-L440 HydrophobicContact CE2-CB 4.43Å; F37-L440 HydrophobicContact CE2-CD2 4.19Å; F37-F444 HydrophobicContact CB-CB 4.27Å; F37-F444 HydrophobicContact CB-CD1 4.44Å; F37-F444 HydrophobicContact CB-CD2 4.04Å; F37-F444 HydrophobicContact CB-CG 4Å; F37-F444 HydrophobicContact CD2-CB 3.9Å; F37-F444 AromaticContact CD2-CD2 3.84Å; F37-F444 HydrophobicContact CD2-CD2 3.84Å; F37-F444 HydrophobicContact CD2-CG 4.13Å; F37-F444 HydrophobicContact CG-CD2 4.42Å
38D98.6Very high98.1Very high62 Ų6239.6 Ų39.633%0.33219%0.193SC..Hα-helixtrans-61.3-40.6177.3-79.4-40000111.4V34 E35 A40 Q42 K96V34-D38 WeakPolarHBondContact O-CB 3.18Å; V34-D38 PolarHBondContact O-N 3.49Å; E35-D38 PolarHBondContact O-N 3.45Å; D38-A40 VanDerWaalsContact C-N 3.33Å; D38-A40 PolarHBondContact O-N 3.42Å; D38-Q42 WeakPolarHBondContact O-CB 3.4Å; D38-Q42 PolarHBondContact O-N 2.97Å; D38-K96 WeakPolarHBondContact OD1-CE 3.16Å; D38-K96 IonicContact OD1-NZ 2.63Å; D38-K96 PolarHBondContact OD1-NZ 3.32Å; D38-K96 IonicContact OD2-NZ 2.7Å; D38-K96 PolarHBondContact OD2-NZ 2.91Å
39H98.6Very high98.1Very high35 Ų3536.1 Ų36.116%0.16218%0.177CC..Hα-helixtrans-60.1-39.7172.6176.894.2000112.6E35 M36 F37 N43 R415 V416 P417 G419 F420E35-H39 WeakPolarHBondContact O-CB 3.29Å; E35-H39 PolarHBondContact O-N 2.97Å; M36-H39 PolarHBondContact O-N 3.44Å; F37-H39 VanDerWaalsContact C-N 3.32Å; F37-H39 PolarHBondContact O-N 2.79Å; H39-N43 WeakPolarHBondContact O-CB 3.47Å; H39-N43 PolarHBondContact O-ND2 3.42Å; H39-R415 PolarHBondContact ND1-NH2 2.92Å; H39-V416 PolarHBondContact CE1-O 3.41Å; H39-V416 VanDerWaalsContact CE1-O 3.31Å; H39-V416 PolarHBondContact NE2-O 3.43Å; H39-P417 PolarHBondContact CE1-O 2.96Å; H39-G419 PolarHBondContact NE2-N 2.87Å; H39-G419 PolarHBondContact NE2-O 2.93Å; H39-F420 AromaticContact CD2-CE2 3.63Å
40A98.4Very high98Very high0 Ų039.7 Ų39.70%020%0.2CC..Hα-helixtrans-78.4-50.1-179.100000112.7M36 F37 D38 N43 Y44 F420 M435 F439 L440 F444M36-A40 WeakPolarHBondContact O-CB 3.42Å; M36-A40 PolarHBondContact O-N 3.08Å; F37-A40 PolarHBondContact O-N 2.96Å; F37-A40 VanDerWaalsContact O-N 3.1Å; D38-A40 VanDerWaalsContact C-N 3.33Å; D38-A40 PolarHBondContact O-N 3.42Å; A40-N43 PolarHBondContact O-N 3.1Å; A40-Y44 PolarHBondContact O-N 2.93Å; A40-F420 HydrophobicContact CB-CD2 3.99Å; A40-F420 HydrophobicContact CB-CE2 4.26Å; A40-M435 HydrophobicContact CB-CE 4.24Å; A40-M435 HydrophobicContact CB-SD 4.18Å; A40-F439 HydrophobicContact CB-CE1 4.49Å; A40-L440 HydrophobicContact CB-CD2 3.53Å; A40-F444 HydrophobicContact CB-CE2 3.91Å; A40-F444 HydrophobicContact CB-CZ 4.44Å
41Y98.5Very high97.9Very high4 Ų438.7 Ų38.72%0.01620%0.2CC..Hα-helixtrans-66.8-43.5-178.8177.1-95.8000112.3F37 N43 Y44 M45 L84 T87 L91 E99 L440F37-Y41 HydrophobicContact CE1-CG 4.09Å; F37-Y41 HydrophobicContact CZ-CD2 4.32Å; F37-Y41 HydrophobicContact CZ-CG 4.21Å; F37-Y41 WeakPolarHBondContact O-CB 3.44Å; F37-Y41 PolarHBondContact O-N 2.83Å; Y41-N43 PolarHBondContact O-N 3.4Å; Y41-Y44 WeakPolarHBondContact O-CB 3.42Å; Y41-Y44 PolarHBondContact O-N 3.5Å; Y41-M45 HydrophobicContact CD1-CG 4.15Å; Y41-M45 HydrophobicContact CE1-CG 3.69Å; Y41-M45 HydrophobicContact CE2-CG 4.19Å; Y41-M45 HydrophobicContact CE2-SD 4.25Å; Y41-M45 WeakPolarHBondContact O-CG 3.5Å; Y41-M45 PolarHBondContact O-N 2.7Å; Y41-L84 HydrophobicContact CE2-CD1 4.39Å; Y41-T87 HydrophobicContact CD2-CG2 3.83Å; Y41-T87 HydrophobicContact CE2-CG2 4.15Å; Y41-L91 HydrophobicContact CE1-CD2 4.24Å; Y41-L91 HydrophobicContact CE2-CD1 4.23Å; Y41-L91 HydrophobicContact CE2-CD2 4.23Å; Y41-E99 HydrophobicContact CE1-CG 3.69Å; Y41-E99 PolarHBondContact OH-OE1 2.99Å; Y41-L440 HydrophobicContact CD2-CD1 4.12Å
42Q98.1Very high97.8Very high91 Ų9134.8 Ų34.843%0.42518%0.179SC..Hα-helixtrans-65.3-39.5178.9-171.961.446.900111.5D38 Y44 M45 D46D38-Q42 WeakPolarHBondContact O-CB 3.4Å; D38-Q42 PolarHBondContact O-N 2.97Å; Q42-Y44 PolarHBondContact O-N 3.44Å; Q42-M45 PolarHBondContact O-N 2.63Å; Q42-D46 WeakPolarHBondContact CG-OD2 3.26Å; Q42-D46 PolarHBondContact NE2-OD1 3.46Å; Q42-D46 PolarHBondContact NE2-OD2 2.75Å; Q42-D46 WeakPolarHBondContact O-CB 3.3Å; Q42-D46 PolarHBondContact O-N 2.82Å
43N98.4Very high97.7Very high23 Ų2333 Ų3312%0.12317%0.17CC..Hα-helixtrans-66.3-34.9173.9-84.2-66.5000112.6H39 A40 Y41 H47 L54 C418H39-N43 WeakPolarHBondContact O-CB 3.47Å; H39-N43 PolarHBondContact O-ND2 3.42Å; A40-N43 PolarHBondContact O-N 3.1Å; Y41-N43 PolarHBondContact O-N 3.4Å; N43-H47 VanDerWaalsContact O-CB 3.28Å; N43-H47 WeakPolarHBondContact O-CB 3.4Å; N43-H47 PolarHBondContact O-N 3.06Å; N43-H47 PolarHBondContact OD1-CD2 2.93Å; N43-L54 HydrophobicContact CB-CD2 4.12Å; N43-C418 WeakPolarHBondContact OD1-CA 3.32Å
44Y98.4Very high97.7Very high0 Ų033 Ų330%017%0.171CC..Hα-helixtrans-61.4-46.6169.2167.1-97.4000111.1A40 Y41 Q42 D46 A48 Y49 A51 L54 T83 L84A40-Y44 PolarHBondContact O-N 2.93Å; Y41-Y44 WeakPolarHBondContact O-CB 3.42Å; Y41-Y44 PolarHBondContact O-N 3.5Å; Q42-Y44 PolarHBondContact O-N 3.44Å; Y44-D46 PolarHBondContact O-N 3.33Å; Y44-A48 HydrophobicContact CD2-CB 3.52Å; Y44-A48 HydrophobicContact CE2-CB 3.86Å; Y44-A48 HydrophobicContact CG-CB 4.38Å; Y44-A48 CarbonylContact O-C 3.43Å; Y44-A48 WeakPolarHBondContact O-CA 3.38Å; Y44-A48 WeakPolarHBondContact O-CB 3.21Å; Y44-A48 PolarHBondContact O-N 3.44Å; Y44-Y49 HydrophobicContact CE1-CD2 4.48Å; Y44-Y49 PolarHBondContact O-N 2.88Å; Y44-A51 WeakPolarHBondContact CE2-O 3.37Å; Y44-A51 PolarHBondContact OH-O 2.94Å; Y44-L54 HydrophobicContact CD2-CB 4.34Å; Y44-T83 HydrophobicContact CD1-CG2 4.03Å; Y44-T83 HydrophobicContact CD2-CG2 3.76Å; Y44-T83 HydrophobicContact CE1-CG2 4.19Å; Y44-T83 HydrophobicContact CE2-CG2 3.96Å; Y44-T83 HydrophobicContact CG-CG2 3.83Å; Y44-L84 HydrophobicContact CE1-CB 4.04Å; Y44-L84 PolarHBondContact OH-N 2.87Å
45M98.1Very high97.7Very high22 Ų2231.8 Ų31.811%0.10816%0.163CC..Hα-helixtrans-66.8-32.4180-68.3-52.6-46.400114.1Y41 Q42 Y49 L84Y41-M45 HydrophobicContact CD1-CG 4.15Å; Y41-M45 HydrophobicContact CE1-CG 3.69Å; Y41-M45 HydrophobicContact CE2-CG 4.19Å; Y41-M45 HydrophobicContact CE2-SD 4.25Å; Y41-M45 WeakPolarHBondContact O-CG 3.5Å; Y41-M45 PolarHBondContact O-N 2.7Å; Q42-M45 PolarHBondContact O-N 2.63Å; M45-Y49 HydrophobicContact CE-CD1 3.86Å; M45-Y49 HydrophobicContact CE-CD2 3.77Å; M45-Y49 HydrophobicContact CE-CE1 4.42Å; M45-Y49 HydrophobicContact CE-CE2 4.33Å; M45-Y49 HydrophobicContact CE-CG 3.51Å; M45-Y49 HydrophobicContact SD-CD2 4.32Å; M45-Y49 HydrophobicContact SD-CG 4.34Å; M45-L84 HydrophobicContact SD-CD1 4.02Å
46D97.9Very high97.6Very high103 Ų10327.6 Ų27.655%0.55114%0.143SC*.Hα-helixtrans-89.9-23-177.9-71.6-24000114Q42 Y44Q42-D46 WeakPolarHBondContact CG-OD2 3.26Å; Q42-D46 PolarHBondContact NE2-OD1 3.46Å; Q42-D46 PolarHBondContact NE2-OD2 2.75Å; Q42-D46 WeakPolarHBondContact O-CB 3.3Å; Q42-D46 PolarHBondContact O-N 2.82Å; Y44-D46 PolarHBondContact O-N 3.33Å
47H97.6Very high97.5Very high80 Ų8031.2 Ų31.237%0.3716%0.162SC..Hα-helixtrans-125-23.7-172.5-62.5-36000115.4N43 L54 R60 G61N43-H47 VanDerWaalsContact O-CB 3.28Å; N43-H47 WeakPolarHBondContact O-CB 3.4Å; N43-H47 PolarHBondContact O-N 3.06Å; N43-H47 PolarHBondContact OD1-CD2 2.93Å; H47-L54 HydrophobicContact CB-CD1 4.08Å; H47-R60 CarbonylContact O-C 3.37Å; H47-R60 VanDerWaalsContact O-CA 3.27Å; H47-R60 WeakPolarHBondContact O-CA 3.4Å; H47-G61 PolarHBondContact O-N 3.08Å; H47-G61 VanDerWaalsContact O-N 3.07Å
48A97.3Very high97.4Very high6 Ų634.7 Ų34.75%0.0518%0.184CC..THydrogen-bonded Turntrans-112.7-44.6-176.500000114.3Y44 A51 L54 G61Y44-A48 HydrophobicContact CD2-CB 3.52Å; Y44-A48 HydrophobicContact CE2-CB 3.86Å; Y44-A48 HydrophobicContact CG-CB 4.38Å; Y44-A48 CarbonylContact O-C 3.43Å; Y44-A48 WeakPolarHBondContact O-CA 3.38Å; Y44-A48 WeakPolarHBondContact O-CB 3.21Å; Y44-A48 PolarHBondContact O-N 3.44Å; A48-A51 WeakPolarHBondContact O-CA 3.43Å; A48-A51 WeakPolarHBondContact O-CB 3.27Å; A48-A51 PolarHBondContact O-N 3.41Å; A48-L54 HydrophobicContact CB-CB 3.97Å; A48-L54 HydrophobicContact CB-CD1 3.76Å; A48-L54 HydrophobicContact CB-CG 4.45Å; A48-G61 VanDerWaalsContact CA-CA 3.49Å
49Y96.9Very high97.4Very high51 Ų5134 Ų3420%0.218%0.183CC..THydrogen-bonded Turntrans-50.4129.8-177.9176.5-95.8000112Y44 M45 L84 R106 D110Y44-Y49 HydrophobicContact CE1-CD2 4.48Å; Y44-Y49 PolarHBondContact O-N 2.88Å; M45-Y49 HydrophobicContact CE-CD1 3.86Å; M45-Y49 HydrophobicContact CE-CD2 3.77Å; M45-Y49 HydrophobicContact CE-CE1 4.42Å; M45-Y49 HydrophobicContact CE-CE2 4.33Å; M45-Y49 HydrophobicContact CE-CG 3.51Å; M45-Y49 HydrophobicContact SD-CD2 4.32Å; M45-Y49 HydrophobicContact SD-CG 4.34Å; Y49-L84 HydrophobicContact CD2-CD2 4.05Å; Y49-L84 HydrophobicContact CE2-CD2 3.54Å; Y49-R106 HydrophobicContact CE2-CB 4.4Å; Y49-R106 WeakPolarHBondContact OH-CB 3.29Å; Y49-D110 VanDerWaalsContact OH-CG 3.23Å; Y49-D110 PolarHBondContact OH-OD2 2.83Å
50P95.4Very high97.2Very high78 Ų7837.2 Ų37.251%0.50619%0.194SC..THydrogen-bonded Turncis-94.317.111.238.4-37.6000115.8S81P50-S81 WeakPolarHBondContact CB-OG 3.47Å; P50-S81 WeakPolarHBondContact O-CA 3.42Å; P50-S81 WeakPolarHBondContact O-CB 3.36Å; P50-S81 PolarHBondContact O-OG 3.3Å
51A95.8Very high97.1Very high14 Ų1437.9 Ų37.912%0.11620%0.201CC..SBendtrans-63162.7176.100000112.7Y44 A48 V63Y44-A51 WeakPolarHBondContact CE2-O 3.37Å; Y44-A51 PolarHBondContact OH-O 2.94Å; A48-A51 WeakPolarHBondContact O-CA 3.43Å; A48-A51 WeakPolarHBondContact O-CB 3.27Å; A48-A51 PolarHBondContact O-N 3.41Å; A51-V63 HydrophobicContact CB-CG2 3.96Å
52D95.8Very high96.8Very high2 Ų238.4 Ų38.41%0.01120%0.203CC..SBendtrans-74.8-36.9-173.5-68.7-40.8000113.4L77 G78 K79 F80 S81 L82 T83D52-L77 HydrophobicContact CB-CB 4.29Å; D52-L77 HydrophobicContact CB-CD2 3.72Å; D52-L77 WeakPolarHBondContact OD2-CA 3.44Å; D52-G78 PolarHBondContact OD2-N 3.41Å; D52-K79 VanDerWaalsContact OD2-CA 3.28Å; D52-K79 WeakPolarHBondContact OD2-CA 3.49Å; D52-K79 PolarHBondContact OD2-N 3.46Å; D52-F80 PolarHBondContact OD1-N 2.96Å; D52-S81 PolarHBondContact OD1-N 3.34Å; D52-L82 HydrophobicContact CB-CB 3.73Å; D52-L82 PolarHBondContact OD1-N 3Å; D52-T83 VanDerWaalsContact O-CB 3.3Å; D52-T83 WeakPolarHBondContact O-CB 3.39Å; D52-T83 PolarHBondContact O-N 3.43Å; D52-T83 PolarHBondContact O-OG1 2.79Å
53E96.2Very high96.2Very high3 Ų336.5 Ų36.51%0.01420%0.197CC..EExtended strand (participates in β ladder)trans-134.4163.8-179.2-72.5-178.1163.200112.1G61 R62 R70 L77E53-G61 CarbonylContact O-C 3.55Å; E53-G61 WeakPolarHBondContact O-CA 3.41Å; E53-R62 HydrophobicContact CB-CB 4.17Å; E53-R62 PolarHBondContact O-N 2.85Å; E53-R70 IonicContact OE1-NH1 2.73Å; E53-R70 IonicContact OE1-NH2 3.2Å; E53-R70 IonicContact OE2-CZ 2.74Å; E53-R70 IonicContact OE2-NH1 3.75Å; E53-R70 PolarHBondContact OE2-NH1 2.82Å; E53-R70 IonicContact OE2-NH2 2.71Å; E53-R70 PolarHBondContact OE2-NH2 3.34Å; E53-L77 HydrophobicContact CG-CD2 3.81Å
54L97.7Very high95.6Very high1 Ų138.2 Ų38.21%0.00520%0.202CC..EExtended strand (participates in β ladder)trans-100.7138.6174.9177.163.2000111.3N43 Y44 H47 A48 P56 C418 M435N43-L54 HydrophobicContact CB-CD2 4.12Å; Y44-L54 HydrophobicContact CD2-CB 4.34Å; H47-L54 HydrophobicContact CB-CD1 4.08Å; A48-L54 HydrophobicContact CB-CB 3.97Å; A48-L54 HydrophobicContact CB-CD1 3.76Å; A48-L54 HydrophobicContact CB-CG 4.45Å; L54-P56 HydrophobicContact CD2-CB 4.43Å; L54-P56 HydrophobicContact CG-CB 4.31Å; L54-P56 WeakPolarHBondContact O-CD 3.5Å; L54-C418 VanDerWaalsContact CD2-O 3.27Å; L54-C418 WeakPolarHBondContact CD2-O 3.43Å; L54-M435 HydrophobicContact CB-CB 4.38Å; L54-M435 HydrophobicContact CB-CE 4.16Å; L54-M435 HydrophobicContact CD2-CE 3.66Å; L54-M435 HydrophobicContact CD2-SD 4.11Å; L54-M435 PolarHBondContact O-N 3.32Å
55M97.4Very high94.7Very high5 Ų541.6 Ų41.63%0.02524%0.237CC..EExtended strand (participates in β ladder)trans-10595.9167.1-69.2-176.4-68.400108L57 C59 R60 G61 R62 E67 D433M55-L57 PolarHBondContact O-N 3.13Å; M55-C59 WeakPolarHBondContact O-CA 3.48Å; M55-C59 PolarHBondContact O-N 3Å; M55-R60 HydrophobicContact CB-CG 4.38Å; M55-R60 WeakPolarHBondContact CB-O 3.49Å; M55-R60 HydrophobicContact CE-CG 3.98Å; M55-R60 PolarHBondContact N-O 3.05Å; M55-R60 PolarHBondContact O-N 3.32Å; M55-G61 WeakPolarHBondContact CE-O 3.37Å; M55-R62 VanDerWaalsContact CE-CA 3.49Å; M55-R62 HydrophobicContact CE-CB 3.92Å; M55-R62 HydrophobicContact CE-CG 4.4Å; M55-R62 HydrophobicContact CG-CB 4.1Å; M55-R62 HydrophobicContact SD-CB 4.08Å; M55-R62 HydrophobicContact SD-CG 4.23Å; M55-E67 HydrophobicContact CE-CG 3.92Å; M55-E67 HydrophobicContact SD-CG 3.83Å; M55-D433 WeakPolarHBondContact CA-OD1 3.45Å; M55-D433 WeakPolarHBondContact CB-OD1 3.38Å; M55-D433 WeakPolarHBondContact CG-O 3.32Å
56P97.4Very high94.1Very high0 Ų047 Ų470%027%0.265CS..THydrogen-bonded Turntrans-85-4.9-162.837.5-40.8000114.3L54 V416 C418 F420 A421 D433 M435L54-P56 HydrophobicContact CD2-CB 4.43Å; L54-P56 HydrophobicContact CG-CB 4.31Å; L54-P56 WeakPolarHBondContact O-CD 3.5Å; P56-V416 HydrophobicContact CB-CG2 3.7Å; P56-V416 HydrophobicContact CG-CG2 4.13Å; P56-V416 WeakPolarHBondContact O-CG2 3.38Å; P56-C418 WeakPolarHBondContact CA-O 3.5Å; P56-C418 WeakPolarHBondContact CB-O 3.27Å; P56-C418 WeakPolarHBondContact O-CB 3.12Å; P56-F420 WeakPolarHBondContact CG-O 3.18Å; P56-A421 HydrophobicContact CG-CB 3.89Å; P56-D433 WeakPolarHBondContact CD-OD1 3.29Å; P56-D433 VanDerWaalsContact N-OD1 3.11Å; P56-M435 HydrophobicContact CG-CB 4.2Å
57L96.9Very high93.6Very high75 Ų7543.1 Ų43.139%0.39324%0.244SC..THydrogen-bonded Turntrans-89.7-37.9169.2-50.9178.2000111.1M55 V416 A421 H431 D433M55-L57 PolarHBondContact O-N 3.13Å; L57-V416 HydrophobicContact CD2-CB 4.22Å; L57-V416 HydrophobicContact CD2-CG1 3.77Å; L57-V416 HydrophobicContact CD2-CG2 4.26Å; L57-A421 HydrophobicContact CD2-CB 3.73Å; L57-A421 HydrophobicContact CG-CB 4.16Å; L57-H431 HydrophobicContact CD1-CB 3.74Å; L57-H431 HydrophobicContact CD2-CB 4.15Å; L57-D433 WeakPolarHBondContact CA-OD1 3.47Å; L57-D433 HydrophobicContact CB-CB 4.19Å; L57-D433 VanDerWaalsContact CB-OD1 3.26Å; L57-D433 WeakPolarHBondContact CB-OD1 3.34Å; L57-D433 HydrophobicContact CD1-CB 3.92Å; L57-D433 HydrophobicContact CG-CB 4.18Å; L57-D433 PolarHBondContact N-OD1 3.14Å
58T96.4Very high93Very high74 Ų7444.8 Ų44.845%0.45426%0.262SS..THydrogen-bonded Turntrans-92.9-2.7175.552.50000114.7R60 D433T58-R60 WeakPolarHBondContact OG1-CG 3.32Å; T58-R60 PolarHBondContact OG1-NE 2.88Å; T58-D433 VanDerWaalsContact CB-OD2 3.29Å; T58-D433 WeakPolarHBondContact CB-OD2 3.27Å; T58-D433 WeakPolarHBondContact CG2-OD2 3.5Å; T58-D433 PolarHBondContact N-OD1 2.9Å; T58-D433 PolarHBondContact N-OD2 2.66Å; T58-D433 PolarHBondContact OG1-OD2 3.13Å
59C97.3Very high92.4Very high47 Ų4749 Ų4932%0.31829%0.291SS..THydrogen-bonded Turntrans55.951.6175.7-52.10000112.9M55 C418M55-C59 WeakPolarHBondContact O-CA 3.48Å; M55-C59 PolarHBondContact O-N 3Å; C59-C418 HydrophobicContact CB-CB 3.71Å; C59-C418 WeakPolarHBondContact CB-SG 3.04Å; C59-C418 WeakPolarHBondContact SG-CB 3.4Å; C59-C418 CovalentContact SG-SG 2.03Å; C59-C418 PolarHBondContact SG-SG 3.12Å
60R96Very high91.7Very high102 Ų10249 Ų4939%0.38529%0.291SS..EExtended strand (participates in β ladder)trans-153.9161.2-176.355.8174.2-164.7120.911.8111.8H47 M55 T58 E67H47-R60 CarbonylContact O-C 3.37Å; H47-R60 VanDerWaalsContact O-CA 3.27Å; H47-R60 WeakPolarHBondContact O-CA 3.4Å; M55-R60 HydrophobicContact CB-CG 4.38Å; M55-R60 WeakPolarHBondContact CB-O 3.49Å; M55-R60 HydrophobicContact CE-CG 3.98Å; M55-R60 PolarHBondContact N-O 3.05Å; M55-R60 PolarHBondContact O-N 3.32Å; T58-R60 WeakPolarHBondContact OG1-CG 3.32Å; T58-R60 PolarHBondContact OG1-NE 2.88Å; R60-E67 IonicContact CZ-OE1 3.41Å; R60-E67 IonicContact NH1-OE1 2.67Å; R60-E67 PolarHBondContact NH1-OE1 3.05Å; R60-E67 IonicContact NH2-OE1 3.61Å; R60-E67 PolarHBondContact NH2-OE1 3.33Å
61G95.6Very high91.2Very high14 Ų1447.3 Ų47.314%0.14429%0.287CS..EExtended strand (participates in β ladder)trans-78.6146.8175.500000114H47 A48 E53 M55H47-G61 PolarHBondContact O-N 3.08Å; H47-G61 VanDerWaalsContact O-N 3.07Å; A48-G61 VanDerWaalsContact CA-CA 3.49Å; E53-G61 CarbonylContact O-C 3.55Å; E53-G61 WeakPolarHBondContact O-CA 3.41Å; M55-G61 WeakPolarHBondContact CE-O 3.37Å
62R92.9Very high90.5Very high15 Ų1552.4 Ų52.46%0.05731%0.312CS..EExtended strand (participates in β ladder)trans-84.7122.8173.3-172.7176.3179.173.96.8110.3E53 M55 E67 P68 R70 D74 L77E53-R62 HydrophobicContact CB-CB 4.17Å; E53-R62 PolarHBondContact O-N 2.85Å; M55-R62 VanDerWaalsContact CE-CA 3.49Å; M55-R62 HydrophobicContact CE-CB 3.92Å; M55-R62 HydrophobicContact CE-CG 4.4Å; M55-R62 HydrophobicContact CG-CB 4.1Å; M55-R62 HydrophobicContact SD-CB 4.08Å; M55-R62 HydrophobicContact SD-CG 4.23Å; R62-E67 WeakPolarHBondContact CA-OE2 3.39Å; R62-E67 WeakPolarHBondContact CG-OE2 3.38Å; R62-P68 PolarHBondContact NH2-O 2.92Å; R62-R70 VanDerWaalsContact NE-CZ 3.32Å; R62-D74 IonicContact CZ-OD1 3.04Å; R62-D74 IonicContact CZ-OD2 2.64Å; R62-D74 IonicContact NE-OD1 2.8Å; R62-D74 PolarHBondContact NE-OD1 3.2Å; R62-D74 IonicContact NE-OD2 3.84Å; R62-D74 IonicContact NH2-OD1 3.36Å; R62-D74 PolarHBondContact NH2-OD1 3.03Å; R62-D74 IonicContact NH2-OD2 3.73Å; R62-D74 PolarHBondContact NH2-OD2 2.95Å; R62-L77 HydrophobicContact CG-CD1 4.09Å
63V85.6Confident89.9Confident51 Ų5155 Ų5531%0.30933%0.328SS..  trans-124.6107.9-177.3-178.40000108.9A51 G65 L66 E67A51-V63 HydrophobicContact CB-CG2 3.96Å; V63-G65 PolarHBondContact O-N 3.4Å; V63-G65 VanDerWaalsContact O-N 3.12Å; V63-L66 HydrophobicContact CB-CD1 3.92Å; V63-L66 HydrophobicContact CB-CG 4.14Å; V63-L66 HydrophobicContact CG1-CD1 4.08Å; V63-L66 HydrophobicContact CG1-CG 4.16Å; V63-L66 PolarHBondContact O-N 2.95Å; V63-E67 PolarHBondContact N-OE2 2.66Å
64R84.1Confident89.6Confident59 Ų5955 Ų5522%0.22333%0.328CS..BIsolated β-bridgetrans-54.7119.1-176.9-170.6170.5177.5-162.91.7111.8D74 D75 L77 K79 V118R64-D74 VanDerWaalsContact CD-O 3.25Å; R64-D74 WeakPolarHBondContact CD-O 3.4Å; R64-D74 HydrophobicContact CG-CB 4.49Å; R64-D74 VanDerWaalsContact CZ-O 3.23Å; R64-D74 PolarHBondContact NE-O 3.49Å; R64-D74 PolarHBondContact NH1-O 3.44Å; R64-D74 VanDerWaalsContact NH1-O 3.1Å; R64-D75 IonicContact CZ-OD1 2.74Å; R64-D75 IonicContact NH1-OD1 3.71Å; R64-D75 IonicContact NH2-OD1 3.31Å; R64-D75 PolarHBondContact NH2-OD1 3.43Å; R64-L77 HydrophobicContact CB-CB 4.25Å; R64-L77 WeakPolarHBondContact CD-O 3.34Å; R64-L77 PolarHBondContact NH1-O 3.27Å; R64-K79 WeakPolarHBondContact O-CE 3.49Å; R64-K79 PolarHBondContact O-NZ 3.42Å; R64-V118 PolarHBondContact NH1-O 2.74Å
65G80.7Confident89.2Confident72 Ų7255.4 Ų55.474%0.74233%0.33SS*.THydrogen-bonded Turntrans106.6-11.4-172.900000115.2V63V63-G65 PolarHBondContact O-N 3.4Å; V63-G65 VanDerWaalsContact O-N 3.12Å
66L84.8Confident88.9Confident134 Ų13455.4 Ų55.470%0.70233%0.331SS*.THydrogen-bonded Turntrans-101-31.9173.8-57.4-171000113V63V63-L66 HydrophobicContact CB-CD1 3.92Å; V63-L66 HydrophobicContact CB-CG 4.14Å; V63-L66 HydrophobicContact CG1-CD1 4.08Å; V63-L66 HydrophobicContact CG1-CG 4.16Å; V63-L66 PolarHBondContact O-N 2.95Å
67E87.6Confident88.7Confident23 Ų2355.4 Ų55.411%0.10733%0.331CS..BIsolated β-bridgetrans-95.8154.9172.9-73.470.7-123.400111.9M55 R60 R62 V63 S69M55-E67 HydrophobicContact CE-CG 3.92Å; M55-E67 HydrophobicContact SD-CG 3.83Å; R60-E67 IonicContact CZ-OE1 3.41Å; R60-E67 IonicContact NH1-OE1 2.67Å; R60-E67 PolarHBondContact NH1-OE1 3.05Å; R60-E67 IonicContact NH2-OE1 3.61Å; R60-E67 PolarHBondContact NH2-OE1 3.33Å; R62-E67 WeakPolarHBondContact CA-OE2 3.39Å; R62-E67 WeakPolarHBondContact CG-OE2 3.38Å; V63-E67 PolarHBondContact N-OE2 2.66Å; E67-S69 PolarHBondContact O-N 3.16Å
68P84.8Confident88.5Confident114 Ų11451.8 Ų51.874%0.7431%0.312SS*.PPolyproline II helixtrans-50.8138.6163.4-25.534.9000111.8R62R62-P68 PolarHBondContact NH2-O 2.92Å
69S84.8Confident88.3Confident94 Ų9453.2 Ų53.266%0.65731%0.312SS*.PPolyproline II helixtrans-63.6138.1-179.6-177.10000111.8E67 G71 D74E67-S69 PolarHBondContact O-N 3.16Å; S69-G71 VanDerWaalsContact C-N 3.26Å; S69-G71 PolarHBondContact OG-N 3.14Å; S69-D74 WeakPolarHBondContact CA-OD2 3.35Å
70R83.1Confident88.2Confident53 Ų5351 Ų5120%0.230%0.297CS..  trans-90.215.7167.7-65177.9-58.7-176.34.7112.2E53 R62 V73 D74E53-R70 IonicContact OE1-NH1 2.73Å; E53-R70 IonicContact OE1-NH2 3.2Å; E53-R70 IonicContact OE2-CZ 2.74Å; E53-R70 IonicContact OE2-NH1 3.75Å; E53-R70 PolarHBondContact OE2-NH1 2.82Å; E53-R70 IonicContact OE2-NH2 2.71Å; E53-R70 PolarHBondContact OE2-NH2 3.34Å; R62-R70 VanDerWaalsContact NE-CZ 3.32Å; R70-V73 HydrophobicContact CB-CB 3.85Å; R70-V73 HydrophobicContact CB-CG1 4.17Å; R70-D74 IonicContact CZ-OD1 3.99Å; R70-D74 PolarHBondContact N-OD2 3.08Å; R70-D74 IonicContact NE-OD1 3.94Å; R70-D74 PolarHBondContact NE-OD1 3.45Å; R70-D74 IonicContact NH2-OD1 3.22Å; R70-D74 PolarHBondContact NH2-OD1 2.96Å
71G84.9Confident88.2Confident41 Ų4146.3 Ų46.342%0.42328%0.28SS..G310 helixtrans68.8-144.4-171.200000111.5S69 V73 D74S69-G71 VanDerWaalsContact C-N 3.26Å; S69-G71 PolarHBondContact OG-N 3.14Å; G71-V73 PolarHBondContact O-N 2.87Å; G71-D74 PolarHBondContact O-N 2.7Å
72D80.7Confident88.2Confident121 Ų12145.8 Ų45.865%0.64727%0.274SS*.G310 helixtrans-51.2-26-178.3-59.8-13.5000113.8D74 D75 R181D72-D74 PolarHBondContact O-N 2.83Å; D72-D75 WeakPolarHBondContact O-CB 3.09Å; D72-D75 PolarHBondContact O-N 3.15Å; D72-R181 IonicContact OD1-CZ 3.36Å; D72-R181 IonicContact OD1-NH2 3.85Å; D72-R181 PolarHBondContact OD1-NH2 2.92Å
73V84Confident88.5Confident57 Ų5745.1 Ų45.135%0.34527%0.271SS..G310 helixtrans-56.6-35.3175.6176.80000112.5R70 G71 D75R70-V73 HydrophobicContact CB-CB 3.85Å; R70-V73 HydrophobicContact CB-CG1 4.17Å; G71-V73 PolarHBondContact O-N 2.87Å; V73-D75 VanDerWaalsContact C-N 3.25Å; V73-D75 PolarHBondContact O-N 3.33Å
74D88.4Confident89.1Confident4 Ų442.7 Ų42.72%0.02126%0.256CS..G310 helixtrans-78.7-5.5179.5-72.6-31.8000113.4R62 R64 S69 R70 G71 D72 A76 L77R62-D74 IonicContact CZ-OD1 3.04Å; R62-D74 IonicContact CZ-OD2 2.64Å; R62-D74 IonicContact NE-OD1 2.8Å; R62-D74 PolarHBondContact NE-OD1 3.2Å; R62-D74 IonicContact NE-OD2 3.84Å; R62-D74 IonicContact NH2-OD1 3.36Å; R62-D74 PolarHBondContact NH2-OD1 3.03Å; R62-D74 IonicContact NH2-OD2 3.73Å; R62-D74 PolarHBondContact NH2-OD2 2.95Å; R64-D74 VanDerWaalsContact CD-O 3.25Å; R64-D74 WeakPolarHBondContact CD-O 3.4Å; R64-D74 HydrophobicContact CG-CB 4.49Å; R64-D74 VanDerWaalsContact CZ-O 3.23Å; R64-D74 PolarHBondContact NE-O 3.49Å; R64-D74 PolarHBondContact NH1-O 3.44Å; R64-D74 VanDerWaalsContact NH1-O 3.1Å; S69-D74 WeakPolarHBondContact CA-OD2 3.35Å; R70-D74 IonicContact CZ-OD1 3.99Å; R70-D74 PolarHBondContact N-OD2 3.08Å; R70-D74 IonicContact NE-OD1 3.94Å; R70-D74 PolarHBondContact NE-OD1 3.45Å; R70-D74 IonicContact NH2-OD1 3.22Å; R70-D74 PolarHBondContact NH2-OD1 2.96Å; G71-D74 PolarHBondContact O-N 2.7Å; D72-D74 PolarHBondContact O-N 2.83Å; D74-A76 PolarHBondContact O-N 2.84Å; D74-L77 HydrophobicContact CB-CD1 4.34Å; D74-L77 WeakPolarHBondContact O-CB 3.31Å; D74-L77 PolarHBondContact O-N 2.58Å; D74-L77 WeakPolarHBondContact OD1-CD1 3.37Å
75D90.1Very high89.8Confident9 Ų939.9 Ų39.95%0.04825%0.246CC..G310 helixtrans-70.5-13.2172.8-74.6-43.2000113.5R64 D72 V73 V119 S120 R181R64-D75 IonicContact CZ-OD1 2.74Å; R64-D75 IonicContact NH1-OD1 3.71Å; R64-D75 IonicContact NH2-OD1 3.31Å; R64-D75 PolarHBondContact NH2-OD1 3.43Å; D72-D75 WeakPolarHBondContact O-CB 3.09Å; D72-D75 PolarHBondContact O-N 3.15Å; V73-D75 VanDerWaalsContact C-N 3.25Å; V73-D75 PolarHBondContact O-N 3.33Å; D75-V119 CarbonylContact O-C 3.58Å; D75-V119 VanDerWaalsContact O-CA 3.26Å; D75-V119 WeakPolarHBondContact O-CA 3.33Å; D75-V119 WeakPolarHBondContact O-CB 3.19Å; D75-S120 PolarHBondContact O-N 3.32Å; D75-R181 IonicContact OD1-NE 3.25Å; D75-R181 IonicContact OD2-CZ 2.73Å; D75-R181 IonicContact OD2-NE 2.73Å; D75-R181 PolarHBondContact OD2-NE 3.2Å; D75-R181 IonicContact OD2-NH2 3.43Å; D75-R181 PolarHBondContact OD2-NH2 2.95Å
76A91.3Very high90.6Very high4 Ų436.4 Ų36.43%0.03321%0.211CC..G310 helixtrans-70.4-19.8165.900000112.8D74 G78 F80 L82 E123D74-A76 PolarHBondContact O-N 2.84Å; A76-G78 PolarHBondContact O-N 3.38Å; A76-F80 WeakPolarHBondContact O-CZ 3.21Å; A76-L82 HydrophobicContact CB-CD2 4.39Å; A76-E123 HydrophobicContact CB-CB 3.88Å; A76-E123 HydrophobicContact CB-CG 4.03Å
77L93.6Very high91.2Very high0 Ų030 Ų300%018%0.177CC..  trans-93.499.1-173.4-45.7-176.6000110.9D52 E53 R62 R64 D74 L82 I117D52-L77 HydrophobicContact CB-CB 4.29Å; D52-L77 HydrophobicContact CB-CD2 3.72Å; D52-L77 WeakPolarHBondContact OD2-CA 3.44Å; E53-L77 HydrophobicContact CG-CD2 3.81Å; R62-L77 HydrophobicContact CG-CD1 4.09Å; R64-L77 HydrophobicContact CB-CB 4.25Å; R64-L77 WeakPolarHBondContact CD-O 3.34Å; R64-L77 PolarHBondContact NH1-O 3.27Å; D74-L77 HydrophobicContact CB-CD1 4.34Å; D74-L77 WeakPolarHBondContact O-CB 3.31Å; D74-L77 PolarHBondContact O-N 2.58Å; D74-L77 WeakPolarHBondContact OD1-CD1 3.37Å; L77-L82 HydrophobicContact CD2-CD2 4.2Å; L77-I117 WeakPolarHBondContact O-CD1 3.47Å
78G91.6Very high91.7Very high0 Ų029 Ų290%017%0.172CC..  trans-106.211.9-17900000115.7D52 A76 N115D52-G78 PolarHBondContact OD2-N 3.41Å; A76-G78 PolarHBondContact O-N 3.38Å; G78-N115 PolarHBondContact O-ND2 3.08Å
79K92.6Very high92.3Very high104 Ų10423.5 Ų23.545%0.45214%0.137SC..SBendtrans60.445.3-178-58.2177.5-179.1179.20112.7D52 R64 N115 I117D52-K79 VanDerWaalsContact OD2-CA 3.28Å; D52-K79 WeakPolarHBondContact OD2-CA 3.49Å; D52-K79 PolarHBondContact OD2-N 3.46Å; R64-K79 WeakPolarHBondContact O-CE 3.49Å; R64-K79 PolarHBondContact O-NZ 3.42Å; K79-N115 PolarHBondContact O-ND2 3.17Å; K79-I117 HydrophobicContact CD-CD1 4.12Å; K79-I117 HydrophobicContact CG-CD1 4.06Å
80F94.1Very high93Very high0 Ų019 Ų190%011%0.105CC..SBendtrans-124.319.8-177.845.3-127.6000112.8D52 A76 L82 I85 V111 L113 V119 V128 L184D52-F80 PolarHBondContact OD1-N 2.96Å; A76-F80 WeakPolarHBondContact O-CZ 3.21Å; F80-L82 HydrophobicContact CD2-CB 4.08Å; F80-L82 HydrophobicContact CE2-CB 3.74Å; F80-L82 HydrophobicContact CE2-CD1 3.89Å; F80-L82 HydrophobicContact CE2-CG 4.29Å; F80-I85 VanDerWaalsContact O-CD1 3.24Å; F80-I85 WeakPolarHBondContact O-CD1 3.3Å; F80-V111 HydrophobicContact CB-CG1 3.88Å; F80-V111 VanDerWaalsContact O-CG2 3.31Å; F80-V111 WeakPolarHBondContact O-CG2 3.45Å; F80-L113 HydrophobicContact CB-CD2 4.35Å; F80-V119 HydrophobicContact CE1-CG1 4.46Å; F80-V128 HydrophobicContact CD2-CG1 4.45Å; F80-V128 HydrophobicContact CD2-CG2 4.05Å; F80-V128 HydrophobicContact CE1-CG2 4.13Å; F80-V128 HydrophobicContact CE2-CG2 3.37Å; F80-V128 HydrophobicContact CZ-CG2 3.44Å; F80-V128 VanDerWaalsContact CZ-CG2 3.44Å; F80-L184 HydrophobicContact CD1-CD1 4.02Å; F80-L184 HydrophobicContact CE1-CD1 4.07Å
81S96.1Very high93.7Very high4 Ų416.5 Ų16.53%0.02810%0.096CC..  trans57.247-177.3-51.70000112.3P50 D52 T83 L84 I85P50-S81 WeakPolarHBondContact CB-OG 3.47Å; P50-S81 WeakPolarHBondContact O-CA 3.42Å; P50-S81 WeakPolarHBondContact O-CB 3.36Å; P50-S81 PolarHBondContact O-OG 3.3Å; D52-S81 PolarHBondContact OD1-N 3.34Å; S81-T83 VanDerWaalsContact C-N 3.34Å; S81-T83 PolarHBondContact O-N 3.43Å; S81-T83 VanDerWaalsContact O-N 3.13Å; S81-L84 WeakPolarHBondContact O-CA 3.45Å; S81-L84 WeakPolarHBondContact O-CB 3.49Å; S81-L84 PolarHBondContact O-N 2.63Å; S81-I85 PolarHBondContact O-N 3.18Å
82L97.1Very high94.2Very high2 Ų214.6 Ų14.61%0.018%0.076CC..Hα-helixtrans-35.1-60.3-173.9175.657000113.6D52 A76 L77 F80 L84 I85 D86 R127 V128D52-L82 HydrophobicContact CB-CB 3.73Å; D52-L82 PolarHBondContact OD1-N 3Å; A76-L82 HydrophobicContact CB-CD2 4.39Å; L77-L82 HydrophobicContact CD2-CD2 4.2Å; F80-L82 HydrophobicContact CD2-CB 4.08Å; F80-L82 HydrophobicContact CE2-CB 3.74Å; F80-L82 HydrophobicContact CE2-CD1 3.89Å; F80-L82 HydrophobicContact CE2-CG 4.29Å; L82-L84 PolarHBondContact O-N 2.94Å; L82-L84 VanDerWaalsContact O-N 3.15Å; L82-I85 PolarHBondContact O-N 3.29Å; L82-D86 WeakPolarHBondContact O-CB 3.38Å; L82-D86 PolarHBondContact O-N 3.27Å; L82-R127 HydrophobicContact CD1-CB 3.68Å; L82-R127 HydrophobicContact CD1-CG 4.4Å; L82-V128 HydrophobicContact CD1-CG2 3.92Å
83T97.9Very high95Very high1 Ų18.9 Ų8.91%0.0065%0.045CC..Hα-helixtrans-58.3-29.4-177-61.10000113.6Y44 D52 S81 T87 S437 L440Y44-T83 HydrophobicContact CD1-CG2 4.03Å; Y44-T83 HydrophobicContact CD2-CG2 3.76Å; Y44-T83 HydrophobicContact CE1-CG2 4.19Å; Y44-T83 HydrophobicContact CE2-CG2 3.96Å; Y44-T83 HydrophobicContact CG-CG2 3.83Å; D52-T83 VanDerWaalsContact O-CB 3.3Å; D52-T83 WeakPolarHBondContact O-CB 3.39Å; D52-T83 PolarHBondContact O-N 3.43Å; D52-T83 PolarHBondContact O-OG1 2.79Å; S81-T83 VanDerWaalsContact C-N 3.34Å; S81-T83 PolarHBondContact O-N 3.43Å; S81-T83 VanDerWaalsContact O-N 3.13Å; T83-T87 VanDerWaalsContact O-CB 3.29Å; T83-T87 WeakPolarHBondContact O-CB 3.46Å; T83-T87 PolarHBondContact O-N 2.65Å; T83-T87 PolarHBondContact O-OG1 2.78Å; T83-S437 WeakPolarHBondContact OG1-CB 3.46Å; T83-L440 HydrophobicContact CG2-CD1 3.6Å; T83-L440 HydrophobicContact CG2-CG 4.44Å
84L98.2Very high95.6Very high0 Ų06.7 Ų6.70%03%0.032CC..Hα-helixtrans-70.6-41.7175.2-178.162.8000112.2Y41 Y44 M45 Y49 S81 L82 L88 A103 R106 V107Y41-L84 HydrophobicContact CE2-CD1 4.39Å; Y44-L84 HydrophobicContact CE1-CB 4.04Å; Y44-L84 PolarHBondContact OH-N 2.87Å; M45-L84 HydrophobicContact SD-CD1 4.02Å; Y49-L84 HydrophobicContact CD2-CD2 4.05Å; Y49-L84 HydrophobicContact CE2-CD2 3.54Å; S81-L84 WeakPolarHBondContact O-CA 3.45Å; S81-L84 WeakPolarHBondContact O-CB 3.49Å; S81-L84 PolarHBondContact O-N 2.63Å; L82-L84 PolarHBondContact O-N 2.94Å; L82-L84 VanDerWaalsContact O-N 3.15Å; L84-L88 WeakPolarHBondContact O-CG 3.37Å; L84-A103 HydrophobicContact CD1-CB 3.78Å; L84-R106 HydrophobicContact CD2-CB 3.8Å; L84-V107 HydrophobicContact CD2-CG2 3.8Å; L84-V107 HydrophobicContact CG-CG2 3.91Å
85I98.4Very high95.9Very high0 Ų011.4 Ų11.40%06%0.057CC..Hα-helixtrans-69.1-47.1179.4-63.5174.5000110F80 S81 L82 T87 L88 V107 V111 V128 L132F80-I85 VanDerWaalsContact O-CD1 3.24Å; F80-I85 WeakPolarHBondContact O-CD1 3.3Å; S81-I85 PolarHBondContact O-N 3.18Å; L82-I85 PolarHBondContact O-N 3.29Å; I85-T87 VanDerWaalsContact C-N 3.27Å; I85-T87 PolarHBondContact O-N 3.03Å; I85-L88 WeakPolarHBondContact O-CB 3.45Å; I85-L88 VanDerWaalsContact O-CG 3.28Å; I85-L88 WeakPolarHBondContact O-CG 3.33Å; I85-L88 PolarHBondContact O-N 3.33Å; I85-V107 HydrophobicContact CG1-CG1 4.39Å; I85-V107 HydrophobicContact CG1-CG2 4.07Å; I85-V111 HydrophobicContact CD1-CG1 4.05Å; I85-V111 HydrophobicContact CD1-CG2 4.27Å; I85-V128 HydrophobicContact CD1-CG1 3.86Å; I85-V128 HydrophobicContact CG2-CG1 4.32Å; I85-L132 HydrophobicContact CG2-CD2 4.15Å; I85-L132 HydrophobicContact CG2-CG 3.91Å
86D98.1Very high96.2Very high0 Ų012.7 Ų12.70%06%0.062CC..Hα-helixtrans-59.4-38.4-177.9-1560.5000111.7L82 L88 S437 F438 A441 H471L82-D86 WeakPolarHBondContact O-CB 3.38Å; L82-D86 PolarHBondContact O-N 3.27Å; D86-L88 VanDerWaalsContact C-N 3.33Å; D86-L88 PolarHBondContact O-N 2.69Å; D86-S437 WeakPolarHBondContact OD2-CB 3.28Å; D86-S437 PolarHBondContact OD2-OG 3.12Å; D86-F438 PolarHBondContact OD2-N 3.36Å; D86-A441 HydrophobicContact CB-CB 4.27Å; D86-A441 VanDerWaalsContact CG-CB 3.48Å; D86-A441 WeakPolarHBondContact O-CB 3.41Å; D86-A441 WeakPolarHBondContact OD1-CB 3.35Å; D86-H471 PolarHBondContact O-CE1 2.83Å; D86-H471 IonicContact OD1-CE1 3.73Å; D86-H471 PolarHBondContact OD1-CE1 3.36Å; D86-H471 IonicContact OD1-NE2 2.69Å; D86-H471 PolarHBondContact OD1-NE2 3.24Å
87T98.1Very high96.4Very high0 Ų013.6 Ų13.60%07%0.067CC..THydrogen-bonded Turntrans-79.5-7.1-177.9-50.80000114.3F37 Y41 T83 I85 D89 T90 L91 L440F37-T87 HydrophobicContact CE2-CG2 3.63Å; F37-T87 HydrophobicContact CZ-CG2 3.47Å; F37-T87 VanDerWaalsContact CZ-CG2 3.47Å; Y41-T87 HydrophobicContact CD2-CG2 3.83Å; Y41-T87 HydrophobicContact CE2-CG2 4.15Å; T83-T87 VanDerWaalsContact O-CB 3.29Å; T83-T87 WeakPolarHBondContact O-CB 3.46Å; T83-T87 PolarHBondContact O-N 2.65Å; T83-T87 PolarHBondContact O-OG1 2.78Å; I85-T87 VanDerWaalsContact C-N 3.27Å; I85-T87 PolarHBondContact O-N 3.03Å; T87-D89 PolarHBondContact O-N 3.27Å; T87-T90 WeakPolarHBondContact O-CB 3.42Å; T87-T90 PolarHBondContact O-N 2.86Å; T87-L91 HydrophobicContact CG2-CG 4.28Å; T87-L91 PolarHBondContact O-N 3Å; T87-L91 VanDerWaalsContact O-N 3.16Å; T87-L440 HydrophobicContact CG2-CB 3.98Å; T87-L440 HydrophobicContact CG2-CD1 4.3Å; T87-L440 VanDerWaalsContact OG1-CB 3.23Å; T87-L440 WeakPolarHBondContact OG1-CB 3.26Å
88L98.4Very high96.5Very high0 Ų018.8 Ų18.80%010%0.099CC..Hα-helixtrans-55.3-51-168.5-79178.5000114.3L84 I85 D86 L91 F100 A103 V104 V107 L156L84-L88 WeakPolarHBondContact O-CG 3.37Å; I85-L88 WeakPolarHBondContact O-CB 3.45Å; I85-L88 VanDerWaalsContact O-CG 3.28Å; I85-L88 WeakPolarHBondContact O-CG 3.33Å; I85-L88 PolarHBondContact O-N 3.33Å; D86-L88 VanDerWaalsContact C-N 3.33Å; D86-L88 PolarHBondContact O-N 2.69Å; L88-L91 PolarHBondContact O-N 2.89Å; L88-F100 HydrophobicContact CB-CE2 4.21Å; L88-F100 HydrophobicContact CD2-CD2 4.28Å; L88-F100 HydrophobicContact CD2-CE2 4.28Å; L88-F100 WeakPolarHBondContact O-CD2 3.5Å; L88-F100 WeakPolarHBondContact O-CE2 3.34Å; L88-A103 HydrophobicContact CD2-CB 3.82Å; L88-V104 HydrophobicContact CD2-CG2 4.01Å; L88-V107 HydrophobicContact CD1-CG2 4.47Å; L88-V107 HydrophobicContact CD2-CG2 4.5Å; L88-L156 HydrophobicContact CD1-CD1 4.27Å; L88-L156 HydrophobicContact CD1-CD2 4.4Å
89D97.4Very high96.8Very high0 Ų021.1 Ų21.10%011%0.11CC..Hα-helixtrans-73.1-30.8-177.470.5-18.4000112.5T87 L91 V92 L93 M138 K445 H471 L472T87-D89 PolarHBondContact O-N 3.27Å; D89-L91 VanDerWaalsContact C-N 3.31Å; D89-L91 PolarHBondContact O-N 3.21Å; D89-V92 PolarHBondContact O-N 2.97Å; D89-L93 PolarHBondContact O-N 3.47Å; D89-M138 HydrophobicContact CB-CG 3.8Å; D89-K445 VanDerWaalsContact CG-NZ 3.3Å; D89-K445 WeakPolarHBondContact OD1-CE 3.48Å; D89-K445 IonicContact OD1-NZ 3.55Å; D89-K445 PolarHBondContact OD1-NZ 3.5Å; D89-K445 IonicContact OD2-NZ 3.69Å; D89-K445 PolarHBondContact OD2-NZ 3.09Å; D89-K445 VanDerWaalsContact OD2-NZ 3.12Å; D89-H471 IonicContact OD1-ND1 3.18Å; D89-H471 VanDerWaalsContact OD2-CA 3.28Å; D89-H471 WeakPolarHBondContact OD2-CA 3.3Å; D89-H471 IonicContact OD2-ND1 3.81Å; D89-L472 PolarHBondContact OD2-N 3.13Å
90T98.1Very high97Very high0 Ų016.1 Ų16.10%09%0.088CC..Hα-helixtrans-60.2-38.9174-50.80000111.8F37 T87 V92 L93 L94 A441 K445F37-T90 HydrophobicContact CD2-CG2 4.2Å; F37-T90 HydrophobicContact CE2-CG2 3.63Å; F37-T90 HydrophobicContact CZ-CG2 4.33Å; T87-T90 WeakPolarHBondContact O-CB 3.42Å; T87-T90 PolarHBondContact O-N 2.86Å; T90-V92 PolarHBondContact O-N 3.37Å; T90-L93 PolarHBondContact O-N 3.44Å; T90-L94 HydrophobicContact CG2-CD1 3.95Å; T90-L94 HydrophobicContact CG2-CG 4.18Å; T90-L94 WeakPolarHBondContact O-CB 3.28Å; T90-L94 VanDerWaalsContact O-CG 3.3Å; T90-L94 WeakPolarHBondContact O-CG 3.49Å; T90-L94 PolarHBondContact O-N 2.97Å; T90-A441 PolarHBondContact OG1-O 3.23Å; T90-K445 HydrophobicContact CG2-CB 4.42Å; T90-K445 WeakPolarHBondContact OG1-CE 3.31Å; T90-K445 PolarHBondContact OG1-NZ 3.42Å
91L98.1Very high97.2Very high0 Ų017.9 Ų17.90%010%0.096CC..Hα-helixtrans-58.9-36.1173.8-67.7170.3000112F37 Y41 T87 L88 D89 K96 E99 F100 A103F37-L91 HydrophobicContact CE1-CD2 3.8Å; F37-L91 HydrophobicContact CZ-CD2 3.74Å; F37-L91 HydrophobicContact CZ-CG 4.45Å; Y41-L91 HydrophobicContact CE1-CD2 4.24Å; Y41-L91 HydrophobicContact CE2-CD1 4.23Å; Y41-L91 HydrophobicContact CE2-CD2 4.23Å; T87-L91 HydrophobicContact CG2-CG 4.28Å; T87-L91 PolarHBondContact O-N 3Å; T87-L91 VanDerWaalsContact O-N 3.16Å; L88-L91 PolarHBondContact O-N 2.89Å; D89-L91 VanDerWaalsContact C-N 3.31Å; D89-L91 PolarHBondContact O-N 3.21Å; L91-K96 HydrophobicContact CD2-CB 4.36Å; L91-K96 HydrophobicContact CD2-CD 4.15Å; L91-K96 WeakPolarHBondContact O-CA 3.4Å; L91-K96 VanDerWaalsContact O-CB 3.32Å; L91-K96 WeakPolarHBondContact O-CB 3.23Å; L91-K96 PolarHBondContact O-N 2.88Å; L91-E99 HydrophobicContact CD2-CG 4.26Å; L91-F100 HydrophobicContact CB-CB 3.94Å; L91-A103 HydrophobicContact CD1-CB 3.74Å
92V96.9Very high97.2Very high1 Ų119 Ų191%0.00611%0.106CC..Hα-helixtrans-76.1-42.5178.6-177.70000111.2D89 T90 L94 N95 F100 M138 M141 L142 P458 F459D89-V92 PolarHBondContact O-N 2.97Å; T90-V92 PolarHBondContact O-N 3.37Å; V92-L94 VanDerWaalsContact C-N 3.32Å; V92-L94 PolarHBondContact O-N 2.99Å; V92-N95 WeakPolarHBondContact O-CA 3.35Å; V92-N95 PolarHBondContact O-N 2.87Å; V92-F100 HydrophobicContact CG2-CB 3.82Å; V92-F100 HydrophobicContact CG2-CD1 3.5Å; V92-F100 VanDerWaalsContact CG2-CD1 3.5Å; V92-F100 HydrophobicContact CG2-CD2 3.47Å; V92-F100 VanDerWaalsContact CG2-CD2 3.47Å; V92-F100 HydrophobicContact CG2-CE1 3.82Å; V92-F100 HydrophobicContact CG2-CE2 3.79Å; V92-F100 HydrophobicContact CG2-CG 3.29Å; V92-F100 HydrophobicContact CG2-CZ 3.94Å; V92-M138 HydrophobicContact CB-CB 4.08Å; V92-M138 HydrophobicContact CB-CG 4.08Å; V92-M138 HydrophobicContact CB-SD 4.05Å; V92-M138 HydrophobicContact CG1-CB 4.17Å; V92-M138 HydrophobicContact CG1-CG 4.31Å; V92-M138 HydrophobicContact CG1-SD 3.8Å; V92-M138 HydrophobicContact CG2-CB 3.89Å; V92-M138 HydrophobicContact CG2-CG 4.35Å; V92-M141 HydrophobicContact CG1-CE 3.79Å; V92-L142 HydrophobicContact CG1-CD1 3.89Å; V92-L142 HydrophobicContact CG1-CD2 4.25Å; V92-L142 HydrophobicContact CG1-CG 4.1Å; V92-L142 HydrophobicContact CG2-CD1 3.84Å; V92-P458 VanDerWaalsContact O-CG 3.29Å; V92-P458 WeakPolarHBondContact O-CG 3.39Å; V92-F459 HydrophobicContact CG1-CE1 4.27Å
93L96.6Very high97.3Very high0 Ų018.9 Ų18.90%011%0.105CC..Hα-helixtrans-59.9-40.5175.6-176.469.2000112.6D89 T90 N95 K445 F448 L449 I457 P458 F459 V461D89-L93 PolarHBondContact O-N 3.47Å; T90-L93 PolarHBondContact O-N 3.44Å; L93-N95 PolarHBondContact O-N 3.13Å; L93-K445 HydrophobicContact CD2-CG 3.62Å; L93-F448 HydrophobicContact CD2-CD1 4.31Å; L93-F448 HydrophobicContact CG-CD1 4.14Å; L93-F448 HydrophobicContact CG-CE1 4.28Å; L93-L449 HydrophobicContact CD1-CD2 4Å; L93-L449 HydrophobicContact CD2-CD1 4.12Å; L93-L449 HydrophobicContact CD2-CD2 4.01Å; L93-L449 HydrophobicContact CD2-CG 3.94Å; L93-I457 HydrophobicContact CD1-CG2 3.83Å; L93-P458 WeakPolarHBondContact O-CD 3.47Å; L93-F459 HydrophobicContact CB-CZ 4.36Å; L93-F459 HydrophobicContact CD1-CE1 4.12Å; L93-F459 HydrophobicContact CD1-CE2 4.34Å; L93-F459 HydrophobicContact CD1-CZ 3.67Å; L93-V461 HydrophobicContact CD1-CG2 4.03Å
94L96.9Very high97.3Very high12 Ų1218.9 Ų18.96%0.06311%0.105CC..THydrogen-bonded Turntrans-76.19.3175.2-61.4-178.7000113.6V34 F37 T90 V92 K96 F448V34-L94 HydrophobicContact CG2-CD2 4.39Å; F37-L94 HydrophobicContact CB-CD1 3.97Å; F37-L94 HydrophobicContact CD1-CD1 3.5Å; F37-L94 VanDerWaalsContact CD1-CD1 3.5Å; F37-L94 HydrophobicContact CD2-CD1 3.5Å; F37-L94 VanDerWaalsContact CD2-CD1 3.5Å; F37-L94 HydrophobicContact CE1-CD1 3.8Å; F37-L94 HydrophobicContact CE2-CD1 3.79Å; F37-L94 HydrophobicContact CG-CD1 3.34Å; F37-L94 HydrophobicContact CZ-CD1 3.93Å; T90-L94 HydrophobicContact CG2-CD1 3.95Å; T90-L94 HydrophobicContact CG2-CG 4.18Å; T90-L94 WeakPolarHBondContact O-CB 3.28Å; T90-L94 VanDerWaalsContact O-CG 3.3Å; T90-L94 WeakPolarHBondContact O-CG 3.49Å; T90-L94 PolarHBondContact O-N 2.97Å; V92-L94 VanDerWaalsContact C-N 3.32Å; V92-L94 PolarHBondContact O-N 2.99Å; L94-K96 VanDerWaalsContact C-N 3.29Å; L94-K96 HydrophobicContact CB-CD 4.12Å; L94-K96 HydrophobicContact CB-CG 4.27Å; L94-K96 PolarHBondContact O-N 2.94Å; L94-F448 HydrophobicContact CD2-CB 3.71Å; L94-F448 HydrophobicContact CD2-CD1 3.82Å; L94-F448 HydrophobicContact CD2-CD2 3.38Å; L94-F448 HydrophobicContact CD2-CE1 4.25Å; L94-F448 HydrophobicContact CD2-CE2 3.85Å; L94-F448 HydrophobicContact CD2-CG 3.36Å; L94-F448 HydrophobicContact CD2-CZ 4.26Å
95N95Very high97.3Very high103 Ų10324.4 Ų24.455%0.55113%0.126SC*.THydrogen-bonded Turntrans57.534.8179.9-161.710.1000114V92 L93 T97 P458V92-N95 WeakPolarHBondContact O-CA 3.35Å; V92-N95 PolarHBondContact O-N 2.87Å; L93-N95 PolarHBondContact O-N 3.13Å; N95-T97 VanDerWaalsContact C-N 3.34Å; N95-T97 PolarHBondContact O-N 3.03Å; N95-P458 HydrophobicContact CB-CG 4.45Å
96K96Very high97.3Very high36 Ų3627.7 Ų27.716%0.15714%0.139CC..  trans-98.245.5177.2-60.7171.2-179.4-74.50110.8F37 D38 L91 L94 T98 E99 F100F37-K96 HydrophobicContact CD1-CD 4.28Å; F37-K96 HydrophobicContact CE1-CD 3.94Å; D38-K96 WeakPolarHBondContact OD1-CE 3.16Å; D38-K96 IonicContact OD1-NZ 2.63Å; D38-K96 PolarHBondContact OD1-NZ 3.32Å; D38-K96 IonicContact OD2-NZ 2.7Å; D38-K96 PolarHBondContact OD2-NZ 2.91Å; L91-K96 HydrophobicContact CD2-CB 4.36Å; L91-K96 HydrophobicContact CD2-CD 4.15Å; L91-K96 WeakPolarHBondContact O-CA 3.4Å; L91-K96 VanDerWaalsContact O-CB 3.32Å; L91-K96 WeakPolarHBondContact O-CB 3.23Å; L91-K96 PolarHBondContact O-N 2.88Å; L94-K96 VanDerWaalsContact C-N 3.29Å; L94-K96 HydrophobicContact CB-CD 4.12Å; L94-K96 HydrophobicContact CB-CG 4.27Å; L94-K96 PolarHBondContact O-N 2.94Å; K96-T98 PolarHBondContact O-N 2.9Å; K96-T98 VanDerWaalsContact O-N 3.08Å; K96-E99 HydrophobicContact CB-CB 4.37Å; K96-E99 PolarHBondContact O-N 2.83Å; K96-F100 PolarHBondContact O-N 3Å
97T95Very high97.3Very high22 Ų2227.7 Ų27.714%0.13514%0.139CC..Hα-helixtrans-56.4-30.2-170.862.70000114.2N95 E101 L142 N148N95-T97 VanDerWaalsContact C-N 3.34Å; N95-T97 PolarHBondContact O-N 3.03Å; T97-E101 WeakPolarHBondContact O-CB 3.3Å; T97-E101 PolarHBondContact O-N 2.82Å; T97-L142 HydrophobicContact CG2-CD1 4.17Å; T97-L142 HydrophobicContact CG2-CD2 3.8Å; T97-N148 PolarHBondContact OG1-OD1 2.79Å
98T95.8Very high97.2Very high109 Ų10930.4 Ų30.467%0.66915%0.153SC*.Hα-helixtrans-71.5-36.3175540000113.4K96 A102K96-T98 PolarHBondContact O-N 2.9Å; K96-T98 VanDerWaalsContact O-N 3.08Å; T98-A102 PolarHBondContact O-N 3.4Å
99E97.1Very high97.1Very high49 Ų4933.2 Ų33.223%0.22917%0.172CC..Hα-helixtrans-79.5-33.8177.3-173.755.2-150.700110.6Y41 L91 K96 A102 A103 R106Y41-E99 HydrophobicContact CE1-CG 3.69Å; Y41-E99 PolarHBondContact OH-OE1 2.99Å; L91-E99 HydrophobicContact CD2-CG 4.26Å; K96-E99 HydrophobicContact CB-CB 4.37Å; K96-E99 PolarHBondContact O-N 2.83Å; E99-A102 CarbonylContact O-C 3.56Å; E99-A102 WeakPolarHBondContact O-CB 3.43Å; E99-A102 PolarHBondContact O-N 3.32Å; E99-A103 VanDerWaalsContact O-CB 3.3Å; E99-A103 WeakPolarHBondContact O-CB 3.46Å; E99-A103 PolarHBondContact O-N 3.27Å; E99-R106 IonicContact OE1-CZ 3.43Å; E99-R106 IonicContact OE1-NH1 2.7Å; E99-R106 PolarHBondContact OE1-NH1 3.06Å; E99-R106 IonicContact OE1-NH2 3.18Å; E99-R106 PolarHBondContact OE1-NH2 3.5Å
100F97.9Very high97Very high0 Ų037 Ų370%019%0.192CC..Hα-helixtrans-55.8-49.6166.2173.4-109.5000111.7L88 L91 V92 K96 A102 A103 V104 G135 M138 A139 L142 M149L88-F100 HydrophobicContact CB-CE2 4.21Å; L88-F100 HydrophobicContact CD2-CD2 4.28Å; L88-F100 HydrophobicContact CD2-CE2 4.28Å; L88-F100 WeakPolarHBondContact O-CD2 3.5Å; L88-F100 WeakPolarHBondContact O-CE2 3.34Å; L91-F100 HydrophobicContact CB-CB 3.94Å; V92-F100 HydrophobicContact CG2-CB 3.82Å; V92-F100 HydrophobicContact CG2-CD1 3.5Å; V92-F100 VanDerWaalsContact CG2-CD1 3.5Å; V92-F100 HydrophobicContact CG2-CD2 3.47Å; V92-F100 VanDerWaalsContact CG2-CD2 3.47Å; V92-F100 HydrophobicContact CG2-CE1 3.82Å; V92-F100 HydrophobicContact CG2-CE2 3.79Å; V92-F100 HydrophobicContact CG2-CG 3.29Å; V92-F100 HydrophobicContact CG2-CZ 3.94Å; K96-F100 PolarHBondContact O-N 3Å; F100-A102 PolarHBondContact O-N 2.94Å; F100-A103 PolarHBondContact O-N 3.31Å; F100-A103 VanDerWaalsContact O-N 3.13Å; F100-V104 HydrophobicContact CD1-CG2 4.46Å; F100-V104 HydrophobicContact CD2-CG2 4.01Å; F100-V104 HydrophobicContact CE1-CG2 4.1Å; F100-V104 HydrophobicContact CE2-CG2 3.62Å; F100-V104 HydrophobicContact CG-CG2 4.43Å; F100-V104 HydrophobicContact CZ-CG2 3.68Å; F100-V104 WeakPolarHBondContact O-CG2 3.44Å; F100-V104 PolarHBondContact O-N 3.4Å; F100-G135 WeakPolarHBondContact CZ-O 3.31Å; F100-M138 HydrophobicContact CZ-CB 4.2Å; F100-A139 HydrophobicContact CE1-CB 4.2Å; F100-A139 HydrophobicContact CZ-CB 4.05Å; F100-L142 HydrophobicContact CD1-CD1 3.66Å; F100-L142 HydrophobicContact CE1-CD1 3.77Å; F100-M149 HydrophobicContact CD1-CE 4.47Å; F100-M149 HydrophobicContact CD1-CG 4.35Å; F100-M149 HydrophobicContact CD1-SD 3.9Å; F100-M149 HydrophobicContact CE1-CE 3.76Å; F100-M149 HydrophobicContact CE1-CG 3.93Å; F100-M149 HydrophobicContact CE1-SD 3.69Å; F100-M149 HydrophobicContact CZ-CE 4.37Å
101E97.4Very high96.9Very high36 Ų3637.3 Ų37.317%0.16820%0.195CC..Hα-helixtrans-64.1-26.1178.6-163-175.3126.700112.8T97 R105 M149 W151T97-E101 WeakPolarHBondContact O-CB 3.3Å; T97-E101 PolarHBondContact O-N 2.82Å; E101-R105 WeakPolarHBondContact O-CG 3.45Å; E101-R105 IonicContact OE1-CZ 3.19Å; E101-R105 IonicContact OE1-NH1 2.81Å; E101-R105 PolarHBondContact OE1-NH1 2.91Å; E101-R105 IonicContact OE1-NH2 2.74Å; E101-R105 PolarHBondContact OE1-NH2 3.13Å; E101-M149 HydrophobicContact CB-SD 3.94Å; E101-M149 HydrophobicContact CG-SD 3.66Å; E101-M149 PolarHBondContact OE2-N 3.37Å; E101-W151 VanDerWaalsContact CD-NE1 3.31Å; E101-W151 HydrophobicContact CG-CZ2 3.9Å; E101-W151 PolarHBondContact OE1-NE1 2.79Å; E101-W151 VanDerWaalsContact OE1-NE1 3.13Å
102A97.6Very high96.7Very high28 Ų2843.1 Ų43.123%0.23122%0.216CC..Hα-helixtrans-77-43.6170.700000112.3T98 E99 F100 R105 R106T98-A102 PolarHBondContact O-N 3.4Å; E99-A102 CarbonylContact O-C 3.56Å; E99-A102 WeakPolarHBondContact O-CB 3.43Å; E99-A102 PolarHBondContact O-N 3.32Å; F100-A102 PolarHBondContact O-N 2.94Å; A102-R105 PolarHBondContact O-N 3.12Å; A102-R106 WeakPolarHBondContact O-CG 3.36Å; A102-R106 PolarHBondContact O-N 3.14Å
103A98.1Very high96.6Very high0 Ų043.4 Ų43.40%022%0.218CC..Hα-helixtrans-60.9-45.9177.700000111.9L84 L88 L91 E99 F100 R105 R106 V107L84-A103 HydrophobicContact CD1-CB 3.78Å; L88-A103 HydrophobicContact CD2-CB 3.82Å; L91-A103 HydrophobicContact CD1-CB 3.74Å; E99-A103 VanDerWaalsContact O-CB 3.3Å; E99-A103 WeakPolarHBondContact O-CB 3.46Å; E99-A103 PolarHBondContact O-N 3.27Å; F100-A103 PolarHBondContact O-N 3.31Å; F100-A103 VanDerWaalsContact O-N 3.13Å; A103-R105 VanDerWaalsContact C-N 3.31Å; A103-R105 PolarHBondContact O-N 2.97Å; A103-R106 WeakPolarHBondContact O-CB 3.49Å; A103-R106 PolarHBondContact O-N 3.18Å; A103-R106 VanDerWaalsContact O-N 3.13Å; A103-V107 WeakPolarHBondContact O-CG2 3.43Å; A103-V107 PolarHBondContact O-N 3.2Å
104V98.4Very high96.5Very high0 Ų047.6 Ų47.60%024%0.24CC..Hα-helixtrans-58.6-43.3174.3177.30000110.6L88 F100 R106 V107 L108 M149 W151 L156L88-V104 HydrophobicContact CD2-CG2 4.01Å; F100-V104 HydrophobicContact CD1-CG2 4.46Å; F100-V104 HydrophobicContact CD2-CG2 4.01Å; F100-V104 HydrophobicContact CE1-CG2 4.1Å; F100-V104 HydrophobicContact CE2-CG2 3.62Å; F100-V104 HydrophobicContact CG-CG2 4.43Å; F100-V104 HydrophobicContact CZ-CG2 3.68Å; F100-V104 WeakPolarHBondContact O-CG2 3.44Å; F100-V104 PolarHBondContact O-N 3.4Å; V104-R106 PolarHBondContact O-N 2.86Å; V104-V107 PolarHBondContact O-N 2.93Å; V104-L108 HydrophobicContact CG1-CD1 4.23Å; V104-L108 HydrophobicContact CG1-CG 4.42Å; V104-L108 VanDerWaalsContact O-CG 3.3Å; V104-L108 WeakPolarHBondContact O-CG 3.3Å; V104-L108 PolarHBondContact O-N 3.03Å; V104-M149 HydrophobicContact CB-CE 4.29Å; V104-M149 HydrophobicContact CG1-CE 4.15Å; V104-M149 HydrophobicContact CG2-CE 4.13Å; V104-W151 HydrophobicContact CG1-CH2 3.96Å; V104-L156 HydrophobicContact CG1-CD1 4.02Å; V104-L156 HydrophobicContact CG1-CD2 4.16Å; V104-L156 HydrophobicContact CG1-CG 4.06Å; V104-L156 HydrophobicContact CG2-CD1 4.04Å
105R97.9Very high96.3Very high117 Ų11748.9 Ų48.944%0.44225%0.247SC..Hα-helixtrans-63.2-38.5176-73.8-176.4-177.4110.5-0.2113.2E101 A102 A103 L108 S109 W151E101-R105 WeakPolarHBondContact O-CG 3.45Å; E101-R105 IonicContact OE1-CZ 3.19Å; E101-R105 IonicContact OE1-NH1 2.81Å; E101-R105 PolarHBondContact OE1-NH1 2.91Å; E101-R105 IonicContact OE1-NH2 2.74Å; E101-R105 PolarHBondContact OE1-NH2 3.13Å; A102-R105 PolarHBondContact O-N 3.12Å; A103-R105 VanDerWaalsContact C-N 3.31Å; A103-R105 PolarHBondContact O-N 2.97Å; R105-L108 PolarHBondContact O-N 3.13Å; R105-S109 PolarHBondContact O-N 3.42Å; R105-S109 PolarHBondContact O-OG 2.84Å; R105-W151 HydrophobicContact CG-CH2 3.91Å; R105-W151 HydrophobicContact CG-CZ2 3.91Å; R105-W151 VanDerWaalsContact NH2-CD1 3.34Å
106R97.9Very high96.3Very high69 Ų6947.7 Ų47.726%0.2624%0.241SC..Hα-helixtrans-63.6-42.8173.7-71.6-174.9-160.7110.9-3111.9Y49 L84 E99 A102 A103 V104 L108 S109 D110Y49-R106 HydrophobicContact CE2-CB 4.4Å; Y49-R106 WeakPolarHBondContact OH-CB 3.29Å; L84-R106 HydrophobicContact CD2-CB 3.8Å; E99-R106 IonicContact OE1-CZ 3.43Å; E99-R106 IonicContact OE1-NH1 2.7Å; E99-R106 PolarHBondContact OE1-NH1 3.06Å; E99-R106 IonicContact OE1-NH2 3.18Å; E99-R106 PolarHBondContact OE1-NH2 3.5Å; A102-R106 WeakPolarHBondContact O-CG 3.36Å; A102-R106 PolarHBondContact O-N 3.14Å; A103-R106 WeakPolarHBondContact O-CB 3.49Å; A103-R106 PolarHBondContact O-N 3.18Å; A103-R106 VanDerWaalsContact O-N 3.13Å; V104-R106 PolarHBondContact O-N 2.86Å; R106-L108 PolarHBondContact O-N 3.31Å; R106-S109 PolarHBondContact O-N 3.28Å; R106-S109 PolarHBondContact O-OG 2.93Å; R106-D110 PolarHBondContact O-N 3.38Å
107V98.1Very high96.1Very high0 Ų046.7 Ų46.70%024%0.237CC..Hα-helixtrans-58.8-48.7174.21710000110.4L84 I85 L88 A103 V104 S109 V111 L132 L156 M159L84-V107 HydrophobicContact CD2-CG2 3.8Å; L84-V107 HydrophobicContact CG-CG2 3.91Å; I85-V107 HydrophobicContact CG1-CG1 4.39Å; I85-V107 HydrophobicContact CG1-CG2 4.07Å; L88-V107 HydrophobicContact CD1-CG2 4.47Å; L88-V107 HydrophobicContact CD2-CG2 4.5Å; A103-V107 WeakPolarHBondContact O-CG2 3.43Å; A103-V107 PolarHBondContact O-N 3.2Å; V104-V107 PolarHBondContact O-N 2.93Å; V107-S109 VanDerWaalsContact C-N 3.3Å; V107-S109 PolarHBondContact O-N 3.1Å; V107-V111 HydrophobicContact CB-CG2 4.33Å; V107-V111 HydrophobicContact CG1-CB 4.41Å; V107-V111 HydrophobicContact CG1-CG2 4.13Å; V107-V111 HydrophobicContact CG2-CG2 4.42Å; V107-V111 VanDerWaalsContact O-CB 3.31Å; V107-V111 WeakPolarHBondContact O-CB 3.43Å; V107-V111 PolarHBondContact O-N 3.07Å; V107-L132 HydrophobicContact CG1-CD2 4.19Å; V107-L156 HydrophobicContact CB-CD2 4.47Å; V107-L156 HydrophobicContact CG1-CD2 3.86Å; V107-M159 HydrophobicContact CG1-CE 3.94Å; V107-M159 HydrophobicContact CG1-SD 4.04Å
108L97.4Very high96.1Very high57 Ų5746.5 Ų46.530%0.29824%0.236SC..Hα-helixtrans-65.8-26.7179.3-63.5179.6000114.1V104 R105 R106 W151 E155 L156 M159V104-L108 HydrophobicContact CG1-CD1 4.23Å; V104-L108 HydrophobicContact CG1-CG 4.42Å; V104-L108 VanDerWaalsContact O-CG 3.3Å; V104-L108 WeakPolarHBondContact O-CG 3.3Å; V104-L108 PolarHBondContact O-N 3.03Å; R105-L108 PolarHBondContact O-N 3.13Å; R106-L108 PolarHBondContact O-N 3.31Å; L108-W151 HydrophobicContact CD1-CH2 4.15Å; L108-W151 HydrophobicContact CD1-CZ3 4.01Å; L108-E155 HydrophobicContact CD1-CB 3.71Å; L108-E155 HydrophobicContact CD1-CG 4.09Å; L108-E155 HydrophobicContact CD2-CB 3.47Å; L108-E155 VanDerWaalsContact CD2-CB 3.47Å; L108-E155 HydrophobicContact CG-CB 4.25Å; L108-L156 HydrophobicContact CD2-CD2 4.41Å; L108-M159 HydrophobicContact CD2-SD 3.69Å
109S96.4Very high96.1Very high58 Ų5841.3 Ų41.341%0.40620%0.204SC..Hα-helixtrans-87.8-42.6179.765.30000113.4R105 R106 V107 R112R105-S109 PolarHBondContact O-N 3.42Å; R105-S109 PolarHBondContact O-OG 2.84Å; R106-S109 PolarHBondContact O-N 3.28Å; R106-S109 PolarHBondContact O-OG 2.93Å; V107-S109 VanDerWaalsContact C-N 3.3Å; V107-S109 PolarHBondContact O-N 3.1Å; S109-R112 VanDerWaalsContact O-CZ 3.31Å; S109-R112 PolarHBondContact O-NH1 3.37Å; S109-R112 PolarHBondContact O-NH2 3.19Å
110D94.6Very high96.1Very high79 Ų7939.9 Ų39.942%0.42220%0.199SC..Hα-helixtrans-110.3-27.9-161-66.216.1000113.3Y49 R106Y49-D110 VanDerWaalsContact OH-CG 3.23Å; Y49-D110 PolarHBondContact OH-OD2 2.83Å; R106-D110 PolarHBondContact O-N 3.38Å
111V95.9Very high96.1Very high8 Ų839.9 Ų39.95%0.04820%0.2CC..  trans-72.8136.9-176.7173.10000111.7F80 I85 V107 L113 M159F80-V111 HydrophobicContact CB-CG1 3.88Å; F80-V111 VanDerWaalsContact O-CG2 3.31Å; F80-V111 WeakPolarHBondContact O-CG2 3.45Å; I85-V111 HydrophobicContact CD1-CG1 4.05Å; I85-V111 HydrophobicContact CD1-CG2 4.27Å; V107-V111 HydrophobicContact CB-CG2 4.33Å; V107-V111 HydrophobicContact CG1-CB 4.41Å; V107-V111 HydrophobicContact CG1-CG2 4.13Å; V107-V111 HydrophobicContact CG2-CG2 4.42Å; V107-V111 VanDerWaalsContact O-CB 3.31Å; V107-V111 WeakPolarHBondContact O-CB 3.43Å; V107-V111 PolarHBondContact O-N 3.07Å; V111-L113 HydrophobicContact CG1-CD2 4.15Å; V111-M159 HydrophobicContact CB-CE 3.96Å; V111-M159 HydrophobicContact CG1-CE 3.71Å
112R94.1Very high96.1Very high121 Ų12139.6 Ų39.646%0.45720%0.198SC..  trans-126138.4174.3-59-62173.9-93.8-7.6110S109 N115S109-R112 VanDerWaalsContact O-CZ 3.31Å; S109-R112 PolarHBondContact O-NH1 3.37Å; S109-R112 PolarHBondContact O-NH2 3.19Å; R112-N115 PolarHBondContact O-ND2 3.32Å
113L95.1Very high96.2Very high8 Ų840.4 Ų40.44%0.04220%0.197CC..SBendtrans-112.3-0.5-177.6-58.3174.8000111.9F80 V111 M159 L163 R166F80-L113 HydrophobicContact CB-CD2 4.35Å; V111-L113 HydrophobicContact CG1-CD2 4.15Å; L113-M159 HydrophobicContact CD1-CB 4.21Å; L113-M159 HydrophobicContact CD1-CE 4.23Å; L113-L163 HydrophobicContact CD1-CB 4.19Å; L113-L163 HydrophobicContact CD2-CD1 4.47Å; L113-R166 WeakPolarHBondContact O-CD 3.22Å; L113-R166 PolarHBondContact O-NE 3.03Å; L113-R166 PolarHBondContact O-NH1 3.36Å
114D94.2Very high96.2Very high88 Ų8840.4 Ų40.447%0.47120%0.197SC..  trans-104.124178.563.5-40.4000113.4K185D114-K185 WeakPolarHBondContact O-CB 3.17Å; D114-K185 WeakPolarHBondContact O-CD 3.34Å
115N92.5Very high96.2Very high39 Ų3940.4 Ų40.421%0.20920%0.197CC..  trans-64.3139.1174.7-69.1-31.6000111.5G78 K79 R112 I117 K185G78-N115 PolarHBondContact O-ND2 3.08Å; K79-N115 PolarHBondContact O-ND2 3.17Å; R112-N115 PolarHBondContact O-ND2 3.32Å; N115-I117 VanDerWaalsContact C-N 3.27Å; N115-I117 HydrophobicContact CB-CB 4.44Å; N115-I117 HydrophobicContact CB-CG2 3.61Å; N115-I117 PolarHBondContact O-N 3.1Å; N115-K185 WeakPolarHBondContact O-CB 3.42Å
116D94.3Very high96.2Very high78 Ų7835 Ų3542%0.41718%0.177SC..SBendtrans-79.675.3171.7-17721.1000111N183 K185 H186 R194D116-N183 PolarHBondContact OD1-ND2 2.86Å; D116-K185 HydrophobicContact CB-CD 4Å; D116-H186 IonicContact OD1-CD2 3.26Å; D116-H186 PolarHBondContact OD1-CD2 3.12Å; D116-H186 IonicContact OD1-NE2 3.58Å; D116-R194 PolarHBondContact O-NH2 2.88Å; D116-R194 IonicContact OD1-CZ 2.7Å; D116-R194 IonicContact OD1-NH2 3.03Å; D116-R194 PolarHBondContact OD1-NH2 3.47Å; D116-R194 IonicContact OD2-NH2 3.32Å; D116-R194 PolarHBondContact OD2-NH2 2.92Å
117I93.1Very high96.2Very high15 Ų1532.6 Ų32.68%0.07717%0.168CC..  trans-145.3138.1-173.5-167159000110.3L77 K79 N115 V119 N183 L184L77-I117 WeakPolarHBondContact O-CD1 3.47Å; K79-I117 HydrophobicContact CD-CD1 4.12Å; K79-I117 HydrophobicContact CG-CD1 4.06Å; N115-I117 VanDerWaalsContact C-N 3.27Å; N115-I117 HydrophobicContact CB-CB 4.44Å; N115-I117 HydrophobicContact CB-CG2 3.61Å; N115-I117 PolarHBondContact O-N 3.1Å; I117-V119 HydrophobicContact CG2-CG1 4.12Å; I117-N183 WeakPolarHBondContact O-CA 3.35Å; I117-L184 HydrophobicContact CG2-CD1 3.98Å; I117-L184 HydrophobicContact CG2-CG 4.45Å; I117-L184 PolarHBondContact O-N 3Å
118V94.6Very high96.3Very high17 Ų1732.7 Ų32.710%0.10317%0.168CC..EExtended strand (participates in β ladder)trans-84127.1173.3178.10000108.6R64 R181 I182 N183 T193 R194 T195R64-V118 PolarHBondContact NH1-O 2.74Å; V118-R181 HydrophobicContact CG1-CB 3.86Å; V118-R181 HydrophobicContact CG1-CG 4.18Å; V118-I182 CarbonylContact C-O 3.45Å; V118-I182 WeakPolarHBondContact CA-O 3.43Å; V118-N183 HydrophobicContact CG2-CB 4.34Å; V118-T193 WeakPolarHBondContact CG2-O 3.46Å; V118-R194 HydrophobicContact CG2-CB 4.08Å; V118-T195 HydrophobicContact CG1-CG2 3.99Å; V118-T195 HydrophobicContact CG2-CG2 3.98Å
119V96Very high96.3Very high0 Ų030 Ų300%015%0.154CC..EExtended strand (participates in β ladder)trans-127.7158.5179.7-60.60000111D75 F80 I117 T124 R181 I182 L184D75-V119 CarbonylContact O-C 3.58Å; D75-V119 VanDerWaalsContact O-CA 3.26Å; D75-V119 WeakPolarHBondContact O-CA 3.33Å; D75-V119 WeakPolarHBondContact O-CB 3.19Å; F80-V119 HydrophobicContact CE1-CG1 4.46Å; I117-V119 HydrophobicContact CG2-CG1 4.12Å; V119-T124 HydrophobicContact CG2-CG2 4.45Å; V119-T124 VanDerWaalsContact CG2-OG1 3.28Å; V119-T124 WeakPolarHBondContact CG2-OG1 3.33Å; V119-R181 CarbonylContact O-C 3.58Å; V119-R181 VanDerWaalsContact O-CA 3.3Å; V119-R181 WeakPolarHBondContact O-CA 3.27Å; V119-I182 HydrophobicContact CG2-CG2 3.99Å; V119-I182 PolarHBondContact N-O 2.73Å; V119-I182 PolarHBondContact O-N 2.83Å; V119-L184 HydrophobicContact CG1-CD1 4.03Å; V119-L184 HydrophobicContact CG1-CG 4.2Å; V119-L184 HydrophobicContact CG2-CD1 4.31Å; V119-L184 HydrophobicContact CG2-CD2 3.75Å; V119-L184 HydrophobicContact CG2-CG 3.75Å
120S96.9Very high96.4Very high19 Ų1927.2 Ų27.213%0.13313%0.134CC..EExtended strand (participates in β ladder)trans-70.9127170.81720000109.4D75 F122 E123 T124 P180D75-S120 PolarHBondContact O-N 3.32Å; S120-F122 VanDerWaalsContact C-N 3.27Å; S120-F122 PolarHBondContact O-N 2.8Å; S120-E123 WeakPolarHBondContact OG-CG 3.36Å; S120-E123 PolarHBondContact OG-N 3.04Å; S120-T124 WeakPolarHBondContact O-CB 3.26Å; S120-T124 PolarHBondContact O-N 3.49Å; S120-T124 PolarHBondContact O-OG1 3.22Å; S120-P180 WeakPolarHBondContact CA-O 3.42Å
121V97.9Very high96.6Very high1 Ų123.4 Ų23.41%0.00611%0.114CC..Hα-helixtrans-64.7-36.2179.2173.20000110.9N125 A170 P178 Y179 P180 I182 M209V121-N125 VanDerWaalsContact O-CB 3.28Å; V121-N125 WeakPolarHBondContact O-CB 3.49Å; V121-N125 PolarHBondContact O-N 3.39Å; V121-N125 VanDerWaalsContact O-N 3.08Å; V121-A170 HydrophobicContact CG1-CB 4.12Å; V121-A170 HydrophobicContact CG2-CB 3.71Å; V121-P178 HydrophobicContact CG1-CB 4.15Å; V121-Y179 WeakPolarHBondContact CG2-O 3.2Å; V121-P180 PolarHBondContact N-O 2.69Å; V121-I182 HydrophobicContact CG2-CB 3.81Å; V121-I182 HydrophobicContact CG2-CG2 3.54Å; V121-M209 HydrophobicContact CG1-CE 3.69Å; V121-M209 HydrophobicContact CG1-SD 4.42Å
122F98.1Very high96.7Very high29 Ų2923 Ų2313%0.12711%0.112CC..Hα-helixtrans-68.1-55.9178.4167.5-104000111.8S120 T124 N125 I126 A204 C205 T208S120-F122 VanDerWaalsContact C-N 3.27Å; S120-F122 PolarHBondContact O-N 2.8Å; F122-T124 VanDerWaalsContact C-N 3.32Å; F122-T124 PolarHBondContact O-N 3.17Å; F122-N125 WeakPolarHBondContact O-CB 3.35Å; F122-N125 PolarHBondContact O-N 3.07Å; F122-N125 VanDerWaalsContact O-N 3.09Å; F122-I126 HydrophobicContact CD1-CD1 4.13Å; F122-I126 HydrophobicContact CD2-CD1 4.5Å; F122-I126 HydrophobicContact CD2-CG2 4.38Å; F122-I126 HydrophobicContact CE1-CD1 3.64Å; F122-I126 HydrophobicContact CE2-CD1 4.06Å; F122-I126 HydrophobicContact CE2-CG2 4.26Å; F122-I126 HydrophobicContact CZ-CD1 3.6Å; F122-I126 PolarHBondContact O-N 3.41Å; F122-A204 HydrophobicContact CE2-CB 4.28Å; F122-C205 HydrophobicContact CB-CB 4.26Å; F122-T208 HydrophobicContact CE2-CG2 3.95Å
123E97.9Very high97Very high46 Ų4617.3 Ų17.322%0.2159%0.09CC..Hα-helixtrans-61.6-41.4-179.5-56.6-69.3159.600111.1A76 S120 N125 R127A76-E123 HydrophobicContact CB-CB 3.88Å; A76-E123 HydrophobicContact CB-CG 4.03Å; S120-E123 WeakPolarHBondContact OG-CG 3.36Å; S120-E123 PolarHBondContact OG-N 3.04Å; E123-N125 VanDerWaalsContact C-N 3.29Å; E123-N125 PolarHBondContact O-N 2.8Å; E123-R127 WeakPolarHBondContact O-CG 3.39Å; E123-R127 PolarHBondContact O-N 3.24Å; E123-R127 VanDerWaalsContact O-N 3.09Å; E123-R127 IonicContact OE2-CZ 3.64Å; E123-R127 VanDerWaalsContact OE2-CZ 3.26Å; E123-R127 IonicContact OE2-NE 2.78Å; E123-R127 PolarHBondContact OE2-NE 3.07Å; E123-R127 IonicContact OE2-NH2 3.72Å; E123-R127 PolarHBondContact OE2-NH2 2.82Å
124T98.3Very high97.1Very high0 Ų016.9 Ų16.90%09%0.088CC..Iπ-helixtrans-66.4-31.9177.8-53.50000111.9V119 S120 F122 V128 L129 L163 L167V119-T124 HydrophobicContact CG2-CG2 4.45Å; V119-T124 VanDerWaalsContact CG2-OG1 3.28Å; V119-T124 WeakPolarHBondContact CG2-OG1 3.33Å; S120-T124 WeakPolarHBondContact O-CB 3.26Å; S120-T124 PolarHBondContact O-N 3.49Å; S120-T124 PolarHBondContact O-OG1 3.22Å; F122-T124 VanDerWaalsContact C-N 3.32Å; F122-T124 PolarHBondContact O-N 3.17Å; T124-V128 HydrophobicContact CG2-CB 4.33Å; T124-V128 HydrophobicContact CG2-CG2 4.3Å; T124-V128 VanDerWaalsContact O-CB 3.31Å; T124-V128 WeakPolarHBondContact O-CB 3.23Å; T124-V128 PolarHBondContact O-N 3.37Å; T124-L129 PolarHBondContact O-N 3.24Å; T124-L163 HydrophobicContact CG2-CD1 3.77Å; T124-L163 HydrophobicContact CG2-CD2 4.12Å; T124-L163 HydrophobicContact CG2-CG 4.33Å; T124-L167 HydrophobicContact CG2-CD1 4.38Å; T124-L167 HydrophobicContact CG2-CD2 4.12Å
125N98.7Very high97.3Very high0 Ų012.7 Ų12.70%07%0.066CC..Iπ-helixtrans-69.4-59.7173179.975.3000111.3V121 F122 E123 R127 L129 G130 L167 T208 M209 E212 F213V121-N125 VanDerWaalsContact O-CB 3.28Å; V121-N125 WeakPolarHBondContact O-CB 3.49Å; V121-N125 PolarHBondContact O-N 3.39Å; V121-N125 VanDerWaalsContact O-N 3.08Å; F122-N125 WeakPolarHBondContact O-CB 3.35Å; F122-N125 PolarHBondContact O-N 3.07Å; F122-N125 VanDerWaalsContact O-N 3.09Å; E123-N125 VanDerWaalsContact C-N 3.29Å; E123-N125 PolarHBondContact O-N 2.8Å; N125-R127 PolarHBondContact O-N 3.31Å; N125-L129 WeakPolarHBondContact O-CB 3.49Å; N125-L129 PolarHBondContact O-N 3.15Å; N125-G130 PolarHBondContact O-N 3.18Å; N125-L167 HydrophobicContact CB-CD1 4.41Å; N125-T208 PolarHBondContact ND2-O 3.3Å; N125-M209 HydrophobicContact CB-CE 3.65Å; N125-M209 HydrophobicContact CB-SD 3.67Å; N125-E212 VanDerWaalsContact ND2-CD 3.28Å; N125-E212 PolarHBondContact ND2-OE2 2.92Å; N125-F213 VanDerWaalsContact OD1-CD1 3.27Å; N125-F213 WeakPolarHBondContact OD1-CD1 3.36Å; N125-F213 WeakPolarHBondContact OD1-CE1 3.44Å
126I98.6Very high97.6Very high4 Ų411.2 Ų11.22%0.0216%0.057CC..Iπ-helixtrans-66.5-40.4-168.966.4-171.1000112.3F122 G130 T208 T468 E469 H471F122-I126 HydrophobicContact CD1-CD1 4.13Å; F122-I126 HydrophobicContact CD2-CD1 4.5Å; F122-I126 HydrophobicContact CD2-CG2 4.38Å; F122-I126 HydrophobicContact CE1-CD1 3.64Å; F122-I126 HydrophobicContact CE2-CD1 4.06Å; F122-I126 HydrophobicContact CE2-CG2 4.26Å; F122-I126 HydrophobicContact CZ-CD1 3.6Å; F122-I126 PolarHBondContact O-N 3.41Å; I126-G130 WeakPolarHBondContact O-CA 3.24Å; I126-T208 HydrophobicContact CG2-CG2 3.87Å; I126-T468 HydrophobicContact CB-CG2 3.99Å; I126-T468 HydrophobicContact CD1-CG2 4.09Å; I126-T468 HydrophobicContact CG2-CG2 3.8Å; I126-E469 HydrophobicContact CB-CB 4.45Å; I126-E469 VanDerWaalsContact CD1-OE2 3.23Å; I126-E469 WeakPolarHBondContact CD1-OE2 3.37Å; I126-E469 WeakPolarHBondContact CG1-OE2 3.38Å; I126-H471 PolarHBondContact O-CD2 3.03Å; I126-H471 PolarHBondContact O-NE2 3.14Å
127R98.4Very high97.7Very high18 Ų187.8 Ų7.87%0.0684%0.04CC..Iπ-helixtrans-90.9-47.4-177.3-41.2-160.3-163.7-175.11.3113.9L82 E123 N125 G131 S437 E469 H471L82-R127 HydrophobicContact CD1-CB 3.68Å; L82-R127 HydrophobicContact CD1-CG 4.4Å; E123-R127 WeakPolarHBondContact O-CG 3.39Å; E123-R127 PolarHBondContact O-N 3.24Å; E123-R127 VanDerWaalsContact O-N 3.09Å; E123-R127 IonicContact OE2-CZ 3.64Å; E123-R127 VanDerWaalsContact OE2-CZ 3.26Å; E123-R127 IonicContact OE2-NE 2.78Å; E123-R127 PolarHBondContact OE2-NE 3.07Å; E123-R127 IonicContact OE2-NH2 3.72Å; E123-R127 PolarHBondContact OE2-NH2 2.82Å; N125-R127 PolarHBondContact O-N 3.31Å; R127-G131 WeakPolarHBondContact O-CA 3.29Å; R127-G131 PolarHBondContact O-N 3.21Å; R127-S437 WeakPolarHBondContact CD-OG 3.31Å; R127-S437 PolarHBondContact NH1-OG 3.39Å; R127-E469 HydrophobicContact CB-CG 4.45Å; R127-E469 WeakPolarHBondContact CD-OE1 3.46Å; R127-E469 VanDerWaalsContact CG-CD 3.5Å; R127-E469 HydrophobicContact CG-CG 3.93Å; R127-E469 VanDerWaalsContact CG-OE1 3.29Å; R127-E469 WeakPolarHBondContact CG-OE1 3.15Å; R127-E469 IonicContact CZ-OE1 2.68Å; R127-E469 IonicContact NE-OE1 2.66Å; R127-E469 PolarHBondContact NE-OE1 3.48Å; R127-H471 PolarHBondContact O-NE2 3.33Å
128V98.4Very high97.8Very high1 Ų17 Ų71%0.0064%0.036CC..Iπ-helixtrans-87.2-50.8-170-165.10000110.9F80 L82 I85 T124 L132 L163F80-V128 HydrophobicContact CD2-CG1 4.45Å; F80-V128 HydrophobicContact CD2-CG2 4.05Å; F80-V128 HydrophobicContact CE1-CG2 4.13Å; F80-V128 HydrophobicContact CE2-CG2 3.37Å; F80-V128 HydrophobicContact CZ-CG2 3.44Å; F80-V128 VanDerWaalsContact CZ-CG2 3.44Å; L82-V128 HydrophobicContact CD1-CG2 3.92Å; I85-V128 HydrophobicContact CD1-CG1 3.86Å; I85-V128 HydrophobicContact CG2-CG1 4.32Å; T124-V128 HydrophobicContact CG2-CB 4.33Å; T124-V128 HydrophobicContact CG2-CG2 4.3Å; T124-V128 VanDerWaalsContact O-CB 3.31Å; T124-V128 WeakPolarHBondContact O-CB 3.23Å; T124-V128 PolarHBondContact O-N 3.37Å; V128-L132 HydrophobicContact CG1-CD1 4.39Å; V128-L132 WeakPolarHBondContact O-CB 3.4Å; V128-L132 WeakPolarHBondContact O-CG 3.3Å; V128-L132 PolarHBondContact O-N 3.28Å; V128-L163 HydrophobicContact CB-CD2 3.79Å; V128-L163 HydrophobicContact CG1-CD2 3.59Å
129L98.7Very high98Very high0 Ų06.2 Ų6.20%03%0.031CC..Iπ-helixtrans-68.7-42.9174.2-176.260.6000110.5T124 N125 L132 L133 A160 L163 E212 F213 L216T124-L129 PolarHBondContact O-N 3.24Å; N125-L129 WeakPolarHBondContact O-CB 3.49Å; N125-L129 PolarHBondContact O-N 3.15Å; L129-L132 PolarHBondContact O-N 3.02Å; L129-L133 HydrophobicContact CD1-CD1 4.04Å; L129-L133 HydrophobicContact CD1-CG 4.21Å; L129-L133 HydrophobicContact CG-CD1 3.87Å; L129-L133 HydrophobicContact CG-CG 4.46Å; L129-L133 WeakPolarHBondContact O-CB 2.93Å; L129-L133 WeakPolarHBondContact O-CG 3.33Å; L129-L133 PolarHBondContact O-N 3.09Å; L129-A160 HydrophobicContact CD1-CB 3.62Å; L129-A160 VanDerWaalsContact CD1-O 3.29Å; L129-A160 WeakPolarHBondContact CD1-O 3.33Å; L129-L163 HydrophobicContact CB-CD2 4.04Å; L129-E212 HydrophobicContact CD2-CB 3.93Å; L129-E212 HydrophobicContact CG-CB 4.07Å; L129-F213 HydrophobicContact CD2-CD1 3.68Å; L129-F213 HydrophobicContact CD2-CE1 3.61Å; L129-L216 HydrophobicContact CD1-CD2 4.22Å; L129-L216 HydrophobicContact CD2-CD2 4.29Å
130G98.5Very high98Very high0 Ų08.3 Ų8.30%04%0.043CC..Hα-helixtrans-55.7-53.3172.100000113.1N125 I126 L132 L133 G134N125-G130 PolarHBondContact O-N 3.18Å; I126-G130 WeakPolarHBondContact O-CA 3.24Å; G130-L132 PolarHBondContact O-N 3.03Å; G130-L133 PolarHBondContact O-N 3.33Å; G130-L133 VanDerWaalsContact O-N 3.13Å; G130-G134 PolarHBondContact O-N 2.89Å
131G98.4Very high97.8Very high0 Ų09.4 Ų9.40%05%0.047CC..Hα-helixtrans-63.7-36.618000000114R127 G135 H471R127-G131 WeakPolarHBondContact O-CA 3.29Å; R127-G131 PolarHBondContact O-N 3.21Å; G131-G135 WeakPolarHBondContact O-CA 3.25Å; G131-G135 PolarHBondContact O-N 3.02Å; G131-H471 VanDerWaalsContact CA-CE1 3.48Å; G131-H471 WeakPolarHBondContact CA-CE1 3.29Å; G131-H471 PolarHBondContact N-CD2 3.26Å; G131-H471 VanDerWaalsContact N-CD2 3.3Å; G131-H471 PolarHBondContact N-NE2 2.94Å; G131-H471 VanDerWaalsContact N-NE2 3.17Å
132L98.8Very high97.7Very high0 Ų010.4 Ų10.40%05%0.052CC..Hα-helixtrans-66.2-38.2172.1-71.3172.2000112.3I85 V107 V128 L129 G130 H136 L156 M159 A160 L163I85-L132 HydrophobicContact CG2-CD2 4.15Å; I85-L132 HydrophobicContact CG2-CG 3.91Å; V107-L132 HydrophobicContact CG1-CD2 4.19Å; V128-L132 HydrophobicContact CG1-CD1 4.39Å; V128-L132 WeakPolarHBondContact O-CB 3.4Å; V128-L132 WeakPolarHBondContact O-CG 3.3Å; V128-L132 PolarHBondContact O-N 3.28Å; L129-L132 PolarHBondContact O-N 3.02Å; G130-L132 PolarHBondContact O-N 3.03Å; L132-H136 VanDerWaalsContact O-CB 3.26Å; L132-H136 WeakPolarHBondContact O-CB 3.37Å; L132-H136 PolarHBondContact O-N 2.89Å; L132-L156 HydrophobicContact CD2-CB 4.44Å; L132-L156 HydrophobicContact CD2-CD2 3.77Å; L132-M159 HydrophobicContact CD1-CB 4.11Å; L132-M159 HydrophobicContact CD2-CB 4.39Å; L132-A160 HydrophobicContact CB-CB 4.06Å; L132-L163 HydrophobicContact CD1-CD2 4.37Å
133L98.7Very high97.5Very high0 Ų011.9 Ų11.90%06%0.059CC..Hα-helixtrans-75.6-39.4178.7-69.5170.7000112.8L129 G130 H136 S137 L157 A160 E212 A215 L216 F219 L473L129-L133 HydrophobicContact CD1-CD1 4.04Å; L129-L133 HydrophobicContact CD1-CG 4.21Å; L129-L133 HydrophobicContact CG-CD1 3.87Å; L129-L133 HydrophobicContact CG-CG 4.46Å; L129-L133 WeakPolarHBondContact O-CB 2.93Å; L129-L133 WeakPolarHBondContact O-CG 3.33Å; L129-L133 PolarHBondContact O-N 3.09Å; G130-L133 PolarHBondContact O-N 3.33Å; G130-L133 VanDerWaalsContact O-N 3.13Å; L133-H136 PolarHBondContact O-N 2.87Å; L133-S137 WeakPolarHBondContact O-CB 3.4Å; L133-S137 PolarHBondContact O-N 2.93Å; L133-S137 PolarHBondContact O-OG 2.97Å; L133-L157 HydrophobicContact CD2-CD1 4.14Å; L133-A160 HydrophobicContact CD2-CB 4.01Å; L133-A160 HydrophobicContact CG-CB 4.29Å; L133-E212 HydrophobicContact CD1-CB 4.01Å; L133-E212 VanDerWaalsContact CD1-O 3.32Å; L133-E212 WeakPolarHBondContact CD1-O 3.2Å; L133-A215 HydrophobicContact CD1-CB 4.26Å; L133-L216 HydrophobicContact CD1-CB 4.27Å; L133-L216 HydrophobicContact CD2-CB 4.36Å; L133-L216 HydrophobicContact CD2-CD1 4.18Å; L133-F219 HydrophobicContact CD2-CD2 3.94Å; L133-F219 HydrophobicContact CD2-CE2 4.38Å; L133-L473 HydrophobicContact CB-CD2 3.94Å
134G98Very high97.2Very high0 Ų016 Ų160%08%0.082CC..Hα-helixtrans-65-46.2171.600000111.3G130 H136 S137 M138G130-G134 PolarHBondContact O-N 2.89Å; G134-H136 PolarHBondContact O-N 2.89Å; G134-S137 WeakPolarHBondContact O-CB 3.28Å; G134-S137 PolarHBondContact O-N 3.27Å; G134-M138 WeakPolarHBondContact O-CG 3.32Å; G134-M138 PolarHBondContact O-N 3.23Å
135G98Very high96.8Very high0 Ų018.5 Ų18.50%011%0.108CC..Hα-helixtrans-58.4-42.5172.300000112.9F100 G131 A139F100-G135 WeakPolarHBondContact CZ-O 3.31Å; G131-G135 WeakPolarHBondContact O-CA 3.25Å; G131-G135 PolarHBondContact O-N 3.02Å; G135-A139 VanDerWaalsContact O-CB 3.28Å; G135-A139 WeakPolarHBondContact O-CB 3.04Å; G135-A139 PolarHBondContact O-N 3.38Å
136H98.4Very high96Very high7 Ų720.8 Ų20.83%0.03213%0.132CC..Hα-helixtrans-61.3-46.6172.8172.136.7000112.3L132 L133 G134 M138 A139 V140 Y152 D154 L156 F219L132-H136 VanDerWaalsContact O-CB 3.26Å; L132-H136 WeakPolarHBondContact O-CB 3.37Å; L132-H136 PolarHBondContact O-N 2.89Å; L133-H136 PolarHBondContact O-N 2.87Å; G134-H136 PolarHBondContact O-N 2.89Å; H136-M138 PolarHBondContact O-N 2.92Å; H136-A139 WeakPolarHBondContact O-CB 3.44Å; H136-A139 PolarHBondContact O-N 3.06Å; H136-A139 VanDerWaalsContact O-N 3.15Å; H136-V140 WeakPolarHBondContact CE1-CG2 3.38Å; H136-V140 WeakPolarHBondContact O-CG2 3.37Å; H136-V140 PolarHBondContact O-N 2.82Å; H136-Y152 AromaticContact ND1-CE1 3.6Å; H136-Y152 AromaticContact ND1-CZ 3.78Å; H136-Y152 PolarHBondContact ND1-OH 3.15Å; H136-Y152 VanDerWaalsContact ND1-OH 3.11Å; H136-D154 IonicContact CE1-OD1 2.79Å; H136-D154 PolarHBondContact CE1-OD1 3.12Å; H136-D154 IonicContact ND1-OD1 3.12Å; H136-L156 HydrophobicContact CB-CB 4.26Å; H136-F219 AromaticContact CD2-CD1 3.89Å; H136-F219 AromaticContact CD2-CG 3.94Å; H136-F219 AromaticContact NE2-CD1 3.59Å; H136-F219 AromaticContact NE2-CE1 3.98Å; H136-F219 AromaticContact NE2-CG 3.95Å
137S96.9Very high94.9Very high6 Ų628.9 Ų28.94%0.04217%0.169CC..Hα-helixtrans-59.6-47.1-180-58.50000111.3L133 G134 A139 V140 M141 F219 P474L133-S137 WeakPolarHBondContact O-CB 3.4Å; L133-S137 PolarHBondContact O-N 2.93Å; L133-S137 PolarHBondContact O-OG 2.97Å; G134-S137 WeakPolarHBondContact O-CB 3.28Å; G134-S137 PolarHBondContact O-N 3.27Å; S137-A139 PolarHBondContact O-N 3.47Å; S137-V140 PolarHBondContact O-N 2.71Å; S137-M141 WeakPolarHBondContact O-CB 3.5Å; S137-M141 PolarHBondContact O-N 3Å; S137-F219 WeakPolarHBondContact OG-CZ 3.18Å; S137-P474 WeakPolarHBondContact OG-CD 3.24Å
138M96.6Very high94.6Very high0 Ų029.5 Ų29.50%017%0.174CC..Hα-helixtrans-64.9-36.5174.8-66.9-64.7106.500112.7D89 V92 F100 G134 H136 M141 L142 F459 Y464 L472D89-M138 HydrophobicContact CB-CG 3.8Å; V92-M138 HydrophobicContact CB-CB 4.08Å; V92-M138 HydrophobicContact CB-CG 4.08Å; V92-M138 HydrophobicContact CB-SD 4.05Å; V92-M138 HydrophobicContact CG1-CB 4.17Å; V92-M138 HydrophobicContact CG1-CG 4.31Å; V92-M138 HydrophobicContact CG1-SD 3.8Å; V92-M138 HydrophobicContact CG2-CB 3.89Å; V92-M138 HydrophobicContact CG2-CG 4.35Å; F100-M138 HydrophobicContact CZ-CB 4.2Å; G134-M138 WeakPolarHBondContact O-CG 3.32Å; G134-M138 PolarHBondContact O-N 3.23Å; H136-M138 PolarHBondContact O-N 2.92Å; M138-M141 HydrophobicContact CE-SD 4.3Å; M138-M141 PolarHBondContact O-N 2.78Å; M138-M141 HydrophobicContact SD-CE 4.08Å; M138-M141 HydrophobicContact SD-SD 4.37Å; M138-L142 WeakPolarHBondContact O-CB 3.31Å; M138-L142 WeakPolarHBondContact O-CG 3.29Å; M138-L142 PolarHBondContact O-N 3.25Å; M138-F459 HydrophobicContact CE-CE1 4.4Å; M138-F459 HydrophobicContact CE-CE2 4.19Å; M138-F459 HydrophobicContact CE-CZ 4.02Å; M138-F459 HydrophobicContact SD-CD1 4.37Å; M138-F459 HydrophobicContact SD-CE1 3.65Å; M138-F459 HydrophobicContact SD-CE2 4.42Å; M138-F459 HydrophobicContact SD-CZ 3.68Å; M138-Y464 HydrophobicContact CE-CD1 4.05Å; M138-Y464 HydrophobicContact CE-CE1 3.34Å; M138-Y464 HydrophobicContact CE-CE2 4.27Å; M138-Y464 VanDerWaalsContact CE-CZ 3.48Å; M138-L472 HydrophobicContact CE-CB 4.08Å; M138-L472 HydrophobicContact CE-CD1 4.01Å; M138-L472 HydrophobicContact SD-CD1 4.22Å
139A97.1Very high94.4Very high0 Ų029.4 Ų29.40%017%0.174CC..Hα-helixtrans-64.9-41.4176.500000112.5F100 G135 H136 S137 K143 M149 Y152F100-A139 HydrophobicContact CE1-CB 4.2Å; F100-A139 HydrophobicContact CZ-CB 4.05Å; G135-A139 VanDerWaalsContact O-CB 3.28Å; G135-A139 WeakPolarHBondContact O-CB 3.04Å; G135-A139 PolarHBondContact O-N 3.38Å; H136-A139 WeakPolarHBondContact O-CB 3.44Å; H136-A139 PolarHBondContact O-N 3.06Å; H136-A139 VanDerWaalsContact O-N 3.15Å; S137-A139 PolarHBondContact O-N 3.47Å; A139-K143 VanDerWaalsContact O-CB 3.22Å; A139-K143 WeakPolarHBondContact O-CB 3.37Å; A139-K143 PolarHBondContact O-N 2.88Å; A139-M149 HydrophobicContact CB-CE 3.66Å; A139-M149 HydrophobicContact CB-CG 4.48Å; A139-Y152 HydrophobicContact CB-CD1 3.87Å; A139-Y152 HydrophobicContact CB-CD2 4.18Å; A139-Y152 HydrophobicContact CB-CE1 3.77Å; A139-Y152 HydrophobicContact CB-CE2 4.09Å; A139-Y152 HydrophobicContact CB-CG 4.1Å
140V95.7Very high94.2Very high43 Ų4335 Ų3526%0.26120%0.2SC..Hα-helixtrans-65.7-47.8174.5173.90000110.6H136 S137 L142 K143 D144 Y152H136-V140 WeakPolarHBondContact CE1-CG2 3.38Å; H136-V140 WeakPolarHBondContact O-CG2 3.37Å; H136-V140 PolarHBondContact O-N 2.82Å; S137-V140 PolarHBondContact O-N 2.71Å; V140-L142 PolarHBondContact O-N 3.35Å; V140-K143 WeakPolarHBondContact O-CB 3.28Å; V140-K143 PolarHBondContact O-N 2.77Å; V140-K143 VanDerWaalsContact O-N 3.08Å; V140-D144 PolarHBondContact O-N 2.76Å; V140-Y152 HydrophobicContact CG2-CE1 4.43Å
141M94.6Very high94.1Very high43 Ų4338.2 Ų38.221%0.21221%0.212CC..Hα-helixtrans-56.4-45.8177.2-177.9-154.870.200112.4V92 S137 M138 K143 D144 G145 F459 Y464V92-M141 HydrophobicContact CG1-CE 3.79Å; S137-M141 WeakPolarHBondContact O-CB 3.5Å; S137-M141 PolarHBondContact O-N 3Å; M138-M141 HydrophobicContact CE-SD 4.3Å; M138-M141 PolarHBondContact O-N 2.78Å; M138-M141 HydrophobicContact SD-CE 4.08Å; M138-M141 HydrophobicContact SD-SD 4.37Å; M141-K143 VanDerWaalsContact C-N 3.31Å; M141-K143 PolarHBondContact O-N 3.32Å; M141-D144 PolarHBondContact O-N 2.95Å; M141-G145 PolarHBondContact O-N 3.2Å; M141-F459 HydrophobicContact CE-CB 4.39Å; M141-F459 HydrophobicContact CE-CD1 3.65Å; M141-F459 HydrophobicContact CE-CE1 4.26Å; M141-F459 HydrophobicContact CE-CG 4.23Å; M141-F459 HydrophobicContact SD-CB 3.5Å; M141-F459 WeakPolarHBondContact SD-CB 3.3Å; M141-F459 HydrophobicContact SD-CD1 3.61Å; M141-F459 HydrophobicContact SD-CD2 4.3Å; M141-F459 HydrophobicContact SD-CE1 4.42Å; M141-F459 HydrophobicContact SD-CG 3.55Å; M141-F459 VanDerWaalsContact SD-CG 3.55Å; M141-Y464 PolarHBondContact SD-OH 2.95Å; M141-Y464 VanDerWaalsContact SD-OH 3.41Å
142L94.7Very high94Very high21 Ų2138.2 Ų38.211%0.1121%0.212CC..Hα-helixtrans-67.3-30.6177.2-74.9176.7000113.3V92 T97 F100 M138 V140 G146 N148 M149V92-L142 HydrophobicContact CG1-CD1 3.89Å; V92-L142 HydrophobicContact CG1-CD2 4.25Å; V92-L142 HydrophobicContact CG1-CG 4.1Å; V92-L142 HydrophobicContact CG2-CD1 3.84Å; T97-L142 HydrophobicContact CG2-CD1 4.17Å; T97-L142 HydrophobicContact CG2-CD2 3.8Å; F100-L142 HydrophobicContact CD1-CD1 3.66Å; F100-L142 HydrophobicContact CE1-CD1 3.77Å; M138-L142 WeakPolarHBondContact O-CB 3.31Å; M138-L142 WeakPolarHBondContact O-CG 3.29Å; M138-L142 PolarHBondContact O-N 3.25Å; V140-L142 PolarHBondContact O-N 3.35Å; L142-G146 PolarHBondContact O-N 3.04Å; L142-N148 HydrophobicContact CB-CB 4.17Å; L142-N148 HydrophobicContact CD1-CB 4.48Å; L142-M149 HydrophobicContact CB-CB 4.28Å; L142-M149 HydrophobicContact CB-CG 3.87Å; L142-M149 HydrophobicContact CD1-CG 4.09Å
143K94.8Very high93.8Very high61 Ų6144.8 Ų44.827%0.26524%0.243SC..Hα-helixtrans-72.6-45176.6175.6179.4167.9-174.80111.3A139 V140 M141 G145 G146 M149 Q150 Y152A139-K143 VanDerWaalsContact O-CB 3.22Å; A139-K143 WeakPolarHBondContact O-CB 3.37Å; A139-K143 PolarHBondContact O-N 2.88Å; V140-K143 WeakPolarHBondContact O-CB 3.28Å; V140-K143 PolarHBondContact O-N 2.77Å; V140-K143 VanDerWaalsContact O-N 3.08Å; M141-K143 VanDerWaalsContact C-N 3.31Å; M141-K143 PolarHBondContact O-N 3.32Å; K143-G145 VanDerWaalsContact C-N 3.33Å; K143-G146 WeakPolarHBondContact O-CA 3.5Å; K143-G146 PolarHBondContact O-N 2.75Å; K143-M149 HydrophobicContact CB-CB 4.22Å; K143-Q150 PolarHBondContact O-NE2 3.03Å; K143-Y152 WeakPolarHBondContact CE-O 3.45Å; K143-Y152 PolarHBondContact NZ-O 3.42Å
144D91.8Very high93.8Very high131 Ų13147.4 Ų47.470%0.70126%0.257SS*.Hα-helixtrans-69.9-30.6176.4-71.6-11.9000112.1V140 M141 G146V140-D144 PolarHBondContact O-N 2.76Å; M141-D144 PolarHBondContact O-N 2.95Å; D144-G146 PolarHBondContact O-N 2.84Å
145G88.3Confident93.8Very high53 Ų5349.7 Ų49.755%0.54627%0.267SS..THydrogen-bonded Turntrans-65.1-10.3166.900000114.6M141 K143 Q147M141-G145 PolarHBondContact O-N 3.2Å; K143-G145 VanDerWaalsContact C-N 3.33Å; G145-Q147 VanDerWaalsContact C-N 3.32Å; G145-Q147 PolarHBondContact O-N 2.9Å
146G82.8Confident93.8Very high49 Ų4949.7 Ų49.751%0.50527%0.267SS..THydrogen-bonded Turntrans74.67.4167.600000116.8L142 K143 D144L142-G146 PolarHBondContact O-N 3.04Å; K143-G146 WeakPolarHBondContact O-CA 3.5Å; K143-G146 PolarHBondContact O-N 2.75Å; D144-G146 PolarHBondContact O-N 2.84Å
147Q76.3Confident93.8Very high173 Ų17350.2 Ų50.281%0.80827%0.27SS*.SBendtrans-112.1-34-174.8-63.6-171.619.300114.3G145G145-Q147 VanDerWaalsContact C-N 3.32Å; G145-Q147 PolarHBondContact O-N 2.9Å
148N90.3Very high93.9Very high31 Ų3155.9 Ų55.917%0.16630%0.296CS..SBendtrans-127.3175.8-178.8-77.998.3000110.4T97 L142 Q150T97-N148 PolarHBondContact OG1-OD1 2.79Å; L142-N148 HydrophobicContact CB-CB 4.17Å; L142-N148 HydrophobicContact CD1-CB 4.48Å; N148-Q150 PolarHBondContact O-N 2.66Å; N148-Q150 PolarHBondContact O-NE2 2.74Å
149M95Very high94Very high0 Ų057.3 Ų57.30%030%0.303CS..  trans55.516.7170-57.7-57.6-73.900116.3F100 E101 V104 A139 L142 K143 W151 Y152F100-M149 HydrophobicContact CD1-CE 4.47Å; F100-M149 HydrophobicContact CD1-CG 4.35Å; F100-M149 HydrophobicContact CD1-SD 3.9Å; F100-M149 HydrophobicContact CE1-CE 3.76Å; F100-M149 HydrophobicContact CE1-CG 3.93Å; F100-M149 HydrophobicContact CE1-SD 3.69Å; F100-M149 HydrophobicContact CZ-CE 4.37Å; E101-M149 HydrophobicContact CB-SD 3.94Å; E101-M149 HydrophobicContact CG-SD 3.66Å; E101-M149 PolarHBondContact OE2-N 3.37Å; V104-M149 HydrophobicContact CB-CE 4.29Å; V104-M149 HydrophobicContact CG1-CE 4.15Å; V104-M149 HydrophobicContact CG2-CE 4.13Å; A139-M149 HydrophobicContact CB-CE 3.66Å; A139-M149 HydrophobicContact CB-CG 4.48Å; L142-M149 HydrophobicContact CB-CB 4.28Å; L142-M149 HydrophobicContact CB-CG 3.87Å; L142-M149 HydrophobicContact CD1-CG 4.09Å; K143-M149 HydrophobicContact CB-CB 4.22Å; M149-W151 HydrophobicContact CE-CH2 4.42Å; M149-W151 HydrophobicContact CE-CZ2 4.04Å; M149-W151 PolarHBondContact O-N 2.96Å; M149-W151 HydrophobicContact SD-CZ2 4.31Å; M149-Y152 HydrophobicContact CE-CD2 3.85Å; M149-Y152 HydrophobicContact CE-CG 4.12Å; M149-Y152 WeakPolarHBondContact O-CB 3.34Å; M149-Y152 PolarHBondContact O-N 3.03Å
150Q94.4Very high94Very high116 Ų11657.3 Ų57.354%0.54230%0.303SS..THydrogen-bonded Turntrans-63-15.8-173.6-62.4-60.3-67.800114.7K143 N148K143-Q150 PolarHBondContact O-NE2 3.03Å; N148-Q150 PolarHBondContact O-N 2.66Å; N148-Q150 PolarHBondContact O-NE2 2.74Å
151W95.7Very high94.2Very high68 Ų6857.9 Ų57.926%0.25830%0.302SS..THydrogen-bonded Turntrans-87-18.9176.356.7-91.1000113.6E101 V104 R105 L108 M149 Q153E101-W151 VanDerWaalsContact CD-NE1 3.31Å; E101-W151 HydrophobicContact CG-CZ2 3.9Å; E101-W151 PolarHBondContact OE1-NE1 2.79Å; E101-W151 VanDerWaalsContact OE1-NE1 3.13Å; V104-W151 HydrophobicContact CG1-CH2 3.96Å; R105-W151 HydrophobicContact CG-CH2 3.91Å; R105-W151 HydrophobicContact CG-CZ2 3.91Å; R105-W151 VanDerWaalsContact NH2-CD1 3.34Å; L108-W151 HydrophobicContact CD1-CH2 4.15Å; L108-W151 HydrophobicContact CD1-CZ3 4.01Å; M149-W151 HydrophobicContact CE-CH2 4.42Å; M149-W151 HydrophobicContact CE-CZ2 4.04Å; M149-W151 PolarHBondContact O-N 2.96Å; M149-W151 HydrophobicContact SD-CZ2 4.31Å; W151-Q153 PolarHBondContact O-NE2 2.84Å
152Y97.3Very high94.4Very high1 Ų158.7 Ų58.70%0.00431%0.307CS..  trans-66.1130.1-169.9-177.9-99.6000111.8H136 A139 V140 K143 M149 D154 E155 L156H136-Y152 AromaticContact ND1-CE1 3.6Å; H136-Y152 AromaticContact ND1-CZ 3.78Å; H136-Y152 PolarHBondContact ND1-OH 3.15Å; H136-Y152 VanDerWaalsContact ND1-OH 3.11Å; A139-Y152 HydrophobicContact CB-CD1 3.87Å; A139-Y152 HydrophobicContact CB-CD2 4.18Å; A139-Y152 HydrophobicContact CB-CE1 3.77Å; A139-Y152 HydrophobicContact CB-CE2 4.09Å; A139-Y152 HydrophobicContact CB-CG 4.1Å; V140-Y152 HydrophobicContact CG2-CE1 4.43Å; K143-Y152 WeakPolarHBondContact CE-O 3.45Å; K143-Y152 PolarHBondContact NZ-O 3.42Å; M149-Y152 HydrophobicContact CE-CD2 3.85Å; M149-Y152 HydrophobicContact CE-CG 4.12Å; M149-Y152 WeakPolarHBondContact O-CB 3.34Å; M149-Y152 PolarHBondContact O-N 3.03Å; Y152-D154 VanDerWaalsContact CE1-CA 3.47Å; Y152-D154 HydrophobicContact CE1-CB 4.42Å; Y152-D154 WeakPolarHBondContact CE1-OD1 3.28Å; Y152-D154 VanDerWaalsContact CZ-CA 3.49Å; Y152-D154 WeakPolarHBondContact OH-CA 3.15Å; Y152-E155 WeakPolarHBondContact CD2-OE2 3.12Å; Y152-E155 VanDerWaalsContact CE2-OE2 3.32Å; Y152-E155 WeakPolarHBondContact CE2-OE2 3.45Å; Y152-L156 HydrophobicContact CE2-CB 4.41Å; Y152-L156 HydrophobicContact CE2-CD1 4.29Å; Y152-L156 HydrophobicContact CE2-CG 4.06Å; Y152-L156 WeakPolarHBondContact OH-CB 3.2Å; Y152-L156 PolarHBondContact OH-N 3.12Å
153Q95.4Very high94.5Very high138 Ų13857.7 Ų57.765%0.64530%0.302SS*.  trans-131.148.9-176.9-75.5161.487.200110W151 E155W151-Q153 PolarHBondContact O-NE2 2.84Å; Q153-E155 VanDerWaalsContact C-OE2 3.3Å; Q153-E155 VanDerWaalsContact N-CD 3.31Å; Q153-E155 PolarHBondContact N-OE1 3.19Å; Q153-E155 PolarHBondContact N-OE2 3.33Å; Q153-E155 PolarHBondContact O-N 3.22Å
154D97.6Very high94.7Very high55 Ų5554.8 Ų54.829%0.29429%0.289SS..SBendtrans64.128.1169.5-47.6-49.9000113.2H136 Y152 L156 L157 H158H136-D154 IonicContact CE1-OD1 2.79Å; H136-D154 PolarHBondContact CE1-OD1 3.12Å; H136-D154 IonicContact ND1-OD1 3.12Å; Y152-D154 VanDerWaalsContact CE1-CA 3.47Å; Y152-D154 HydrophobicContact CE1-CB 4.42Å; Y152-D154 WeakPolarHBondContact CE1-OD1 3.28Å; Y152-D154 VanDerWaalsContact CZ-CA 3.49Å; Y152-D154 WeakPolarHBondContact OH-CA 3.15Å; D154-L156 PolarHBondContact O-N 2.75Å; D154-L157 HydrophobicContact CB-CB 4.22Å; D154-L157 HydrophobicContact CB-CD2 4.49Å; D154-L157 WeakPolarHBondContact O-CA 3.41Å; D154-L157 WeakPolarHBondContact O-CB 3.22Å; D154-L157 PolarHBondContact O-N 3.44Å; D154-H158 PolarHBondContact O-N 2.65Å; D154-H158 PolarHBondContact O-ND1 2.96Å
155E97.9Very high95Very high47 Ų4752.6 Ų52.622%0.2228%0.277CS..Hα-helixtrans-64-35.6-175.5-58.292.9154.200112.9L108 Y152 Q153 L157 H158 M159L108-E155 HydrophobicContact CD1-CB 3.71Å; L108-E155 HydrophobicContact CD1-CG 4.09Å; L108-E155 HydrophobicContact CD2-CB 3.47Å; L108-E155 VanDerWaalsContact CD2-CB 3.47Å; L108-E155 HydrophobicContact CG-CB 4.25Å; Y152-E155 WeakPolarHBondContact CD2-OE2 3.12Å; Y152-E155 VanDerWaalsContact CE2-OE2 3.32Å; Y152-E155 WeakPolarHBondContact CE2-OE2 3.45Å; Q153-E155 VanDerWaalsContact C-OE2 3.3Å; Q153-E155 VanDerWaalsContact N-CD 3.31Å; Q153-E155 PolarHBondContact N-OE1 3.19Å; Q153-E155 PolarHBondContact N-OE2 3.33Å; Q153-E155 PolarHBondContact O-N 3.22Å; E155-L157 VanDerWaalsContact C-N 3.32Å; E155-H158 PolarHBondContact O-N 3.13Å; E155-M159 PolarHBondContact O-N 3.04Å; E155-M159 VanDerWaalsContact O-N 3.13Å
156L98.6Very high95.4Very high0 Ų052.7 Ų52.70%026%0.261CS..Hα-helixtrans-68.8-32.1173.1-61.1171.7000111.7L88 V104 V107 L108 L132 H136 Y152 D154 M159 A160L88-L156 HydrophobicContact CD1-CD1 4.27Å; L88-L156 HydrophobicContact CD1-CD2 4.4Å; V104-L156 HydrophobicContact CG1-CD1 4.02Å; V104-L156 HydrophobicContact CG1-CD2 4.16Å; V104-L156 HydrophobicContact CG1-CG 4.06Å; V104-L156 HydrophobicContact CG2-CD1 4.04Å; V107-L156 HydrophobicContact CB-CD2 4.47Å; V107-L156 HydrophobicContact CG1-CD2 3.86Å; L108-L156 HydrophobicContact CD2-CD2 4.41Å; L132-L156 HydrophobicContact CD2-CB 4.44Å; L132-L156 HydrophobicContact CD2-CD2 3.77Å; H136-L156 HydrophobicContact CB-CB 4.26Å; Y152-L156 HydrophobicContact CE2-CB 4.41Å; Y152-L156 HydrophobicContact CE2-CD1 4.29Å; Y152-L156 HydrophobicContact CE2-CG 4.06Å; Y152-L156 WeakPolarHBondContact OH-CB 3.2Å; Y152-L156 PolarHBondContact OH-N 3.12Å; D154-L156 PolarHBondContact O-N 2.75Å; L156-M159 PolarHBondContact O-N 3.29Å; L156-A160 WeakPolarHBondContact O-CB 2.94Å; L156-A160 PolarHBondContact O-N 3.49Å
157L98.6Very high96.1Very high18 Ų1850.4 Ų50.49%0.09424%0.237CC..Hα-helixtrans-68.5-37.5174.9-17864.1000111.3L133 D154 E155 M159 A160 K161 L216 F219 T220L133-L157 HydrophobicContact CD2-CD1 4.14Å; D154-L157 HydrophobicContact CB-CB 4.22Å; D154-L157 HydrophobicContact CB-CD2 4.49Å; D154-L157 WeakPolarHBondContact O-CA 3.41Å; D154-L157 WeakPolarHBondContact O-CB 3.22Å; D154-L157 PolarHBondContact O-N 3.44Å; E155-L157 VanDerWaalsContact C-N 3.32Å; L157-M159 VanDerWaalsContact C-N 3.35Å; L157-A160 PolarHBondContact O-N 3.35Å; L157-K161 WeakPolarHBondContact O-CB 3.42Å; L157-K161 PolarHBondContact O-N 3.22Å; L157-L216 HydrophobicContact CD1-CD1 4.1Å; L157-F219 HydrophobicContact CD1-CB 3.48Å; L157-F219 VanDerWaalsContact CD1-CB 3.48Å; L157-F219 HydrophobicContact CD1-CG 4.25Å; L157-F219 HydrophobicContact CD2-CB 3.88Å; L157-F219 HydrophobicContact CG-CB 4.34Å; L157-T220 HydrophobicContact CD1-CG2 3.73Å; L157-T220 HydrophobicContact CD2-CG2 4.24Å; L157-T220 HydrophobicContact CG-CG2 3.97Å
158H98.3Very high97.1Very high125 Ų12543.4 Ų43.458%0.57921%0.205SC*.Hα-helixtrans-63-40.9173.2-65.9110.6000111.6D154 E155 K161 D162D154-H158 PolarHBondContact O-N 2.65Å; D154-H158 PolarHBondContact O-ND1 2.96Å; E155-H158 PolarHBondContact O-N 3.13Å; H158-K161 PolarHBondContact O-N 3.36Å; H158-D162 PolarHBondContact O-N 2.91Å
159M98.4Very high97.4Very high31 Ų3144.2 Ų44.215%0.15321%0.212CC..Hα-helixtrans-66-42.9172.5-68.9-179.170.300112.6V107 L108 V111 L113 L132 E155 L156 L157 K161 D162 L163V107-M159 HydrophobicContact CG1-CE 3.94Å; V107-M159 HydrophobicContact CG1-SD 4.04Å; L108-M159 HydrophobicContact CD2-SD 3.69Å; V111-M159 HydrophobicContact CB-CE 3.96Å; V111-M159 HydrophobicContact CG1-CE 3.71Å; L113-M159 HydrophobicContact CD1-CB 4.21Å; L113-M159 HydrophobicContact CD1-CE 4.23Å; L132-M159 HydrophobicContact CD1-CB 4.11Å; L132-M159 HydrophobicContact CD2-CB 4.39Å; E155-M159 PolarHBondContact O-N 3.04Å; E155-M159 VanDerWaalsContact O-N 3.13Å; L156-M159 PolarHBondContact O-N 3.29Å; L157-M159 VanDerWaalsContact C-N 3.35Å; M159-K161 VanDerWaalsContact C-N 3.27Å; M159-K161 PolarHBondContact O-N 3.18Å; M159-D162 PolarHBondContact O-N 3.43Å; M159-L163 PolarHBondContact O-N 3.47Å
160A98.6Very high97.5Very high0 Ų044.2 Ų44.20%021%0.212CC..Hα-helixtrans-58.7-39174.800000111.6L129 L132 L133 L156 L157 G164 L216L129-A160 HydrophobicContact CD1-CB 3.62Å; L129-A160 VanDerWaalsContact CD1-O 3.29Å; L129-A160 WeakPolarHBondContact CD1-O 3.33Å; L132-A160 HydrophobicContact CB-CB 4.06Å; L133-A160 HydrophobicContact CD2-CB 4.01Å; L133-A160 HydrophobicContact CG-CB 4.29Å; L156-A160 WeakPolarHBondContact O-CB 2.94Å; L156-A160 PolarHBondContact O-N 3.49Å; L157-A160 PolarHBondContact O-N 3.35Å; A160-G164 PolarHBondContact O-N 3.37Å; A160-L216 HydrophobicContact CB-CD1 3.94Å
161K98.6Very high97.7Very high54 Ų5439 Ų3924%0.23519%0.188CC..Hα-helixtrans-68.7-42.7175.5-170.1166.8-172.8148.60112.7L157 H158 M159 L163 G164 L165 L216 T220 D222 F225L157-K161 WeakPolarHBondContact O-CB 3.42Å; L157-K161 PolarHBondContact O-N 3.22Å; H158-K161 PolarHBondContact O-N 3.36Å; M159-K161 VanDerWaalsContact C-N 3.27Å; M159-K161 PolarHBondContact O-N 3.18Å; K161-L163 VanDerWaalsContact C-N 3.34Å; K161-G164 PolarHBondContact O-N 3.16Å; K161-L165 HydrophobicContact CG-CD1 4.23Å; K161-L165 HydrophobicContact CG-CG 4.47Å; K161-L165 WeakPolarHBondContact O-CB 3.36Å; K161-L165 VanDerWaalsContact O-CG 3.24Å; K161-L165 WeakPolarHBondContact O-CG 3.49Å; K161-L165 PolarHBondContact O-N 2.95Å; K161-L216 HydrophobicContact CB-CD1 4.28Å; K161-T220 HydrophobicContact CB-CG2 4.17Å; K161-T220 HydrophobicContact CD-CG2 3.9Å; K161-T220 HydrophobicContact CG-CG2 4.33Å; K161-D222 WeakPolarHBondContact CE-OD2 3.39Å; K161-D222 VanDerWaalsContact NZ-CB 3.31Å; K161-D222 IonicContact NZ-OD2 3.26Å; K161-D222 PolarHBondContact NZ-OD2 3.39Å; K161-F225 HydrophobicContact CG-CE2 4.45Å; K161-F225 HydrophobicContact CG-CZ 4.14Å
162D98.3Very high97.6Very high61 Ų6139.7 Ų39.733%0.32620%0.196SC..Hα-helixtrans-60.3-44.2174.6-174.764.1000111.2H158 M159 L165 R166H158-D162 PolarHBondContact O-N 2.91Å; M159-D162 PolarHBondContact O-N 3.43Å; D162-L165 PolarHBondContact O-N 3.49Å; D162-R166 WeakPolarHBondContact O-CG 3.33Å; D162-R166 PolarHBondContact O-N 3.15Å; D162-R166 IonicContact OD1-CZ 3.4Å; D162-R166 IonicContact OD1-NE 2.94Å; D162-R166 IonicContact OD1-NH2 3.88Å; D162-R166 PolarHBondContact OD1-NH2 3Å; D162-R166 IonicContact OD2-CZ 3.09Å; D162-R166 IonicContact OD2-NE 3.17Å; D162-R166 PolarHBondContact OD2-NE 3.49Å; D162-R166 IonicContact OD2-NH2 3.76Å; D162-R166 PolarHBondContact OD2-NH2 3.22Å
163L98.3Very high97.5Very high0 Ų040.6 Ų40.60%020%0.202CC..Hα-helixtrans-62.3-48.2175-173.356.6000112.5L113 T124 V128 L129 L132 M159 K161 L165 R166 L167 L184L113-L163 HydrophobicContact CD1-CB 4.19Å; L113-L163 HydrophobicContact CD2-CD1 4.47Å; T124-L163 HydrophobicContact CG2-CD1 3.77Å; T124-L163 HydrophobicContact CG2-CD2 4.12Å; T124-L163 HydrophobicContact CG2-CG 4.33Å; V128-L163 HydrophobicContact CB-CD2 3.79Å; V128-L163 HydrophobicContact CG1-CD2 3.59Å; L129-L163 HydrophobicContact CB-CD2 4.04Å; L132-L163 HydrophobicContact CD1-CD2 4.37Å; M159-L163 PolarHBondContact O-N 3.47Å; K161-L163 VanDerWaalsContact C-N 3.34Å; L163-L165 VanDerWaalsContact C-N 3.28Å; L163-L165 PolarHBondContact O-N 3.07Å; L163-R166 WeakPolarHBondContact O-CA 3.34Å; L163-R166 WeakPolarHBondContact O-CB 3.41Å; L163-R166 PolarHBondContact O-N 3.08Å; L163-L167 HydrophobicContact CD1-CG 4.49Å; L163-L167 HydrophobicContact CG-CD1 4.44Å; L163-L167 WeakPolarHBondContact O-CG 3.39Å; L163-L167 PolarHBondContact O-N 2.86Å; L163-L184 HydrophobicContact CD1-CD2 4.05Å
164G97.8Very high97.5Very high0 Ų038.6 Ų38.60%020%0.203CC..Hα-helixtrans-56.3-43176.600000112.1A160 K161 R166 L167 L168A160-G164 PolarHBondContact O-N 3.37Å; K161-G164 PolarHBondContact O-N 3.16Å; G164-R166 VanDerWaalsContact C-N 3.31Å; G164-R166 PolarHBondContact O-N 3.45Å; G164-L167 PolarHBondContact O-N 3.5Å; G164-L167 VanDerWaalsContact O-N 3.16Å; G164-L168 WeakPolarHBondContact O-CG 3.33Å; G164-L168 PolarHBondContact O-N 2.83Å
165L98.1Very high97.4Very high85 Ų8536.9 Ų36.945%0.44520%0.195SC..Hα-helixtrans-64-32.9175.9-70.4171.6000112.8K161 D162 L163 L168 P169 F225K161-L165 HydrophobicContact CG-CD1 4.23Å; K161-L165 HydrophobicContact CG-CG 4.47Å; K161-L165 WeakPolarHBondContact O-CB 3.36Å; K161-L165 VanDerWaalsContact O-CG 3.24Å; K161-L165 WeakPolarHBondContact O-CG 3.49Å; K161-L165 PolarHBondContact O-N 2.95Å; D162-L165 PolarHBondContact O-N 3.49Å; L163-L165 VanDerWaalsContact C-N 3.28Å; L163-L165 PolarHBondContact O-N 3.07Å; L165-L168 HydrophobicContact CD2-CD1 4.03Å; L165-P169 WeakPolarHBondContact O-CD 3.47Å; L165-F225 HydrophobicContact CD2-CE1 4.1Å; L165-F225 HydrophobicContact CD2-CZ 3.97Å; L165-F225 HydrophobicContact CG-CE1 4.26Å; L165-F225 HydrophobicContact CG-CZ 4.09Å
166R97.3Very high97.3Very high55 Ų5535.3 Ų35.321%0.20819%0.192CC..Hα-helixtrans-72.1-29.3172.8-67.3166.1-167.6-75.4-7.4113.4L113 D162 L163 G164 P169 I182 L184L113-R166 WeakPolarHBondContact O-CD 3.22Å; L113-R166 PolarHBondContact O-NE 3.03Å; L113-R166 PolarHBondContact O-NH1 3.36Å; D162-R166 WeakPolarHBondContact O-CG 3.33Å; D162-R166 PolarHBondContact O-N 3.15Å; D162-R166 IonicContact OD1-CZ 3.4Å; D162-R166 IonicContact OD1-NE 2.94Å; D162-R166 IonicContact OD1-NH2 3.88Å; D162-R166 PolarHBondContact OD1-NH2 3Å; D162-R166 IonicContact OD2-CZ 3.09Å; D162-R166 IonicContact OD2-NE 3.17Å; D162-R166 PolarHBondContact OD2-NE 3.49Å; D162-R166 IonicContact OD2-NH2 3.76Å; D162-R166 PolarHBondContact OD2-NH2 3.22Å; L163-R166 WeakPolarHBondContact O-CA 3.34Å; L163-R166 WeakPolarHBondContact O-CB 3.41Å; L163-R166 PolarHBondContact O-N 3.08Å; G164-R166 VanDerWaalsContact C-N 3.31Å; G164-R166 PolarHBondContact O-N 3.45Å; R166-P169 WeakPolarHBondContact O-CD 3.32Å; R166-I182 WeakPolarHBondContact O-CD1 3.45Å; R166-L184 WeakPolarHBondContact CD-O 3.44Å; R166-L184 PolarHBondContact NH1-O 2.89Å
167L97.8Very high97.3Very high0 Ų035.3 Ų35.30%019%0.192CC..Hα-helixtrans-81.7-30.2177.7-64.5-177.5000113.1T124 N125 L163 G164 P169 A170 I182 F213T124-L167 HydrophobicContact CG2-CD1 4.38Å; T124-L167 HydrophobicContact CG2-CD2 4.12Å; N125-L167 HydrophobicContact CB-CD1 4.41Å; L163-L167 HydrophobicContact CD1-CG 4.49Å; L163-L167 HydrophobicContact CG-CD1 4.44Å; L163-L167 WeakPolarHBondContact O-CG 3.39Å; L163-L167 PolarHBondContact O-N 2.86Å; G164-L167 PolarHBondContact O-N 3.5Å; G164-L167 VanDerWaalsContact O-N 3.16Å; L167-P169 VanDerWaalsContact C-N 3.35Å; L167-A170 VanDerWaalsContact O-CB 3.23Å; L167-A170 WeakPolarHBondContact O-CB 3.31Å; L167-A170 PolarHBondContact O-N 3.3Å; L167-I182 HydrophobicContact CD2-CG2 3.85Å; L167-F213 HydrophobicContact CB-CZ 4.01Å; L167-F213 HydrophobicContact CD1-CE1 4.26Å; L167-F213 HydrophobicContact CD1-CZ 4.38Å
168L97.2Very high97.2Very high27 Ų2734.5 Ų34.514%0.14119%0.187CC..G310 helixtrans-48.9-40.3179.8-78.5179.6000115.5G164 L165 A170 F171 F213 V224 F225 H228G164-L168 WeakPolarHBondContact O-CG 3.33Å; G164-L168 PolarHBondContact O-N 2.83Å; L165-L168 HydrophobicContact CD2-CD1 4.03Å; L168-A170 PolarHBondContact O-N 3.45Å; L168-A170 VanDerWaalsContact O-N 3.13Å; L168-F171 PolarHBondContact O-N 2.95Å; L168-F171 VanDerWaalsContact O-N 3.1Å; L168-F213 HydrophobicContact CD2-CE2 4.28Å; L168-V224 HydrophobicContact CD1-CG1 4.02Å; L168-V224 HydrophobicContact CD1-CG2 3.97Å; L168-F225 HydrophobicContact CD1-CD1 4.07Å; L168-F225 HydrophobicContact CD1-CE1 3.78Å; L168-F225 HydrophobicContact CD2-CD1 4.01Å; L168-F225 HydrophobicContact CG-CD1 4Å; L168-F225 HydrophobicContact CG-CE1 4.04Å; L168-H228 HydrophobicContact CD2-CB 4.14Å
169P96.6Very high97.2Very high47 Ų4729.5 Ų29.531%0.30516%0.164SC..G310 helixtrans-57-24.7176-26.335000114.7L165 R166 L167 F171 N172 I182 V188L165-P169 WeakPolarHBondContact O-CD 3.47Å; R166-P169 WeakPolarHBondContact O-CD 3.32Å; L167-P169 VanDerWaalsContact C-N 3.35Å; P169-F171 PolarHBondContact O-N 2.95Å; P169-N172 WeakPolarHBondContact O-CB 3.28Å; P169-N172 PolarHBondContact O-N 3.26Å; P169-N172 VanDerWaalsContact O-N 3.16Å; P169-I182 HydrophobicContact CB-CD1 4.05Å; P169-I182 HydrophobicContact CG-CD1 4.48Å; P169-V188 HydrophobicContact CB-CG2 4.26Å; P169-V188 VanDerWaalsContact O-CG2 3.26Å; P169-V188 WeakPolarHBondContact O-CG2 3.39Å
170A97.3Very high97Very high0 Ų029.3 Ų29.30%017%0.165CC..G310 helixtrans-61.7-31.9176.600000112.3V121 L167 L168 N172 P178 Y179 I182V121-A170 HydrophobicContact CG1-CB 4.12Å; V121-A170 HydrophobicContact CG2-CB 3.71Å; L167-A170 VanDerWaalsContact O-CB 3.23Å; L167-A170 WeakPolarHBondContact O-CB 3.31Å; L167-A170 PolarHBondContact O-N 3.3Å; L168-A170 PolarHBondContact O-N 3.45Å; L168-A170 VanDerWaalsContact O-N 3.13Å; A170-N172 PolarHBondContact O-N 2.84Å; A170-P178 HydrophobicContact CB-CB 4.07Å; A170-P178 CarbonylContact O-C 3.56Å; A170-P178 VanDerWaalsContact O-CA 3.3Å; A170-P178 WeakPolarHBondContact O-CA 3.3Å; A170-Y179 WeakPolarHBondContact O-CD2 3.41Å; A170-Y179 PolarHBondContact O-N 2.95Å; A170-I182 HydrophobicContact CB-CD1 4.02Å
171F97.4Very high96.9Very high8 Ų832.5 Ų32.54%0.03518%0.177CC..G310 helixtrans-77.32.6179.8-64.1-102.1000113.3L168 P169 T173 G176 P178 M209 F213 H228 A232L168-F171 PolarHBondContact O-N 2.95Å; L168-F171 VanDerWaalsContact O-N 3.1Å; P169-F171 PolarHBondContact O-N 2.95Å; F171-T173 PolarHBondContact O-N 3.35Å; F171-G176 WeakPolarHBondContact CD1-O 3.39Å; F171-P178 HydrophobicContact CD1-CB 4.27Å; F171-P178 HydrophobicContact CD1-CG 4.5Å; F171-P178 HydrophobicContact CD2-CB 4.32Å; F171-P178 HydrophobicContact CE1-CB 4.23Å; F171-P178 HydrophobicContact CE1-CG 4.14Å; F171-P178 HydrophobicContact CE2-CB 4.26Å; F171-P178 HydrophobicContact CG-CB 4.32Å; F171-P178 HydrophobicContact CZ-CB 4.23Å; F171-P178 HydrophobicContact CZ-CG 4.31Å; F171-M209 HydrophobicContact CE2-CE 4.02Å; F171-M209 HydrophobicContact CZ-CB 4.28Å; F171-M209 HydrophobicContact CZ-CE 3.75Å; F171-M209 HydrophobicContact CZ-CG 4.07Å; F171-F213 HydrophobicContact CD2-CE2 4.36Å; F171-F213 HydrophobicContact CE2-CD2 4.42Å; F171-F213 AromaticContact CE2-CE2 3.43Å; F171-F213 HydrophobicContact CE2-CE2 3.43Å; F171-F213 VanDerWaalsContact CE2-CE2 3.43Å; F171-F213 AromaticContact CE2-CZ 3.79Å; F171-F213 HydrophobicContact CE2-CZ 3.79Å; F171-F213 HydrophobicContact CZ-CD2 4.24Å; F171-F213 AromaticContact CZ-CE2 3.64Å; F171-F213 HydrophobicContact CZ-CE2 3.64Å; F171-F213 HydrophobicContact CZ-CZ 4.15Å; F171-H228 HydrophobicContact CB-CB 4.42Å; F171-H228 HydrophobicContact CD1-CB 3.95Å; F171-H228 HydrophobicContact CD2-CB 4.47Å; F171-H228 HydrophobicContact CE1-CB 4.29Å; F171-H228 HydrophobicContact CG-CB 4.04Å; F171-A232 HydrophobicContact CE1-CB 4.26Å
172N94.3Very high96.8Very high81 Ų8130 Ų3043%0.43317%0.166SC..  trans-84.350.4-176.1-155.3-23.9000112.3P169 A170 R189P169-N172 WeakPolarHBondContact O-CB 3.28Å; P169-N172 PolarHBondContact O-N 3.26Å; P169-N172 VanDerWaalsContact O-N 3.16Å; A170-N172 PolarHBondContact O-N 2.84Å; N172-R189 PolarHBondContact ND2-NH2 2.94Å; N172-R189 PolarHBondContact OD1-NH2 2.75Å
173T95.6Very high96.7Very high21 Ų2127.1 Ų27.113%0.12915%0.15CC..SBendtrans-106.2175.2178.766.40000111.1F171 S175 G176 L177 Y179 I253F171-T173 PolarHBondContact O-N 3.35Å; T173-S175 VanDerWaalsContact C-N 3.26Å; T173-S175 PolarHBondContact O-N 2.85Å; T173-S175 PolarHBondContact OG1-OG 3.39Å; T173-G176 PolarHBondContact OG1-N 3.49Å; T173-L177 WeakPolarHBondContact CB-O 3.46Å; T173-L177 WeakPolarHBondContact CG2-O 3.5Å; T173-L177 PolarHBondContact OG1-N 2.78Å; T173-L177 PolarHBondContact OG1-O 3.41Å; T173-Y179 HydrophobicContact CG2-CD2 3.78Å; T173-Y179 HydrophobicContact CG2-CE1 4.41Å; T173-Y179 HydrophobicContact CG2-CE2 3.56Å; T173-Y179 HydrophobicContact CG2-CG 4.27Å; T173-I253 HydrophobicContact CG2-CB 4.12Å; T173-I253 HydrophobicContact CG2-CD1 3.75Å; T173-I253 HydrophobicContact CG2-CG1 3.81Å
174S94.6Very high96.6Very high95 Ų9527.2 Ų27.266%0.66415%0.151SC*.SBendtrans-74.4-16178.4-470000113.7H254S174-H254 PolarHBondContact OG-ND1 3.2Å
175S95.6Very high96.4Very high19 Ų1932.8 Ų32.813%0.13318%0.175CC..SBendtrans-101.2-25.1177.2590000114T173 L177 F235 I253T173-S175 VanDerWaalsContact C-N 3.26Å; T173-S175 PolarHBondContact O-N 2.85Å; T173-S175 PolarHBondContact OG1-OG 3.39Å; S175-L177 VanDerWaalsContact C-N 3.31Å; S175-L177 WeakPolarHBondContact OG-CB 2.96Å; S175-L177 VanDerWaalsContact OG-CG 3.32Å; S175-L177 WeakPolarHBondContact OG-CG 3.09Å; S175-L177 PolarHBondContact OG-N 3Å; S175-F235 VanDerWaalsContact CB-CE1 3.44Å; S175-I253 VanDerWaalsContact CB-O 3.29Å; S175-I253 WeakPolarHBondContact CB-O 3.21Å; S175-I253 PolarHBondContact N-O 3.01Å; S175-I253 PolarHBondContact OG-O 3.23Å
176G95.9Very high96.3Very high14 Ų1431 Ų3114%0.14417%0.165CC..SBendtrans84.1-0.3-164.600000114.1F171 T173F171-G176 WeakPolarHBondContact CD1-O 3.39Å; T173-G176 PolarHBondContact OG1-N 3.49Å
177L97.9Very high96.1Very high0 Ų029 Ų290%016%0.161CC..PPolyproline II helixtrans-70.3143.7165.2-57.1177.4000109.5T173 S175 A206 A232 F235 L236 I251 I253T173-L177 WeakPolarHBondContact CB-O 3.46Å; T173-L177 WeakPolarHBondContact CG2-O 3.5Å; T173-L177 PolarHBondContact OG1-N 2.78Å; T173-L177 PolarHBondContact OG1-O 3.41Å; S175-L177 VanDerWaalsContact C-N 3.31Å; S175-L177 WeakPolarHBondContact OG-CB 2.96Å; S175-L177 VanDerWaalsContact OG-CG 3.32Å; S175-L177 WeakPolarHBondContact OG-CG 3.09Å; S175-L177 PolarHBondContact OG-N 3Å; L177-A206 HydrophobicContact CB-CB 4.36Å; L177-A206 HydrophobicContact CD2-CB 4.03Å; L177-A232 HydrophobicContact CD2-CB 4.1Å; L177-A232 WeakPolarHBondContact CD2-O 3.42Å; L177-F235 HydrophobicContact CD1-CD1 3.72Å; L177-F235 HydrophobicContact CD1-CE1 3.82Å; L177-F235 HydrophobicContact CD2-CB 4.26Å; L177-F235 HydrophobicContact CD2-CD1 3.93Å; L177-F235 HydrophobicContact CD2-CG 4.49Å; L177-F235 HydrophobicContact CG-CD1 3.75Å; L177-F235 HydrophobicContact CG-CE1 4.19Å; L177-F235 HydrophobicContact CG-CG 4.48Å; L177-L236 HydrophobicContact CD1-CD2 4.36Å; L177-L236 HydrophobicContact CD2-CD1 4.5Å; L177-L236 HydrophobicContact CD2-CD2 3.96Å; L177-L236 HydrophobicContact CD2-CG 3.77Å; L177-I251 HydrophobicContact CD1-CD1 4.1Å; L177-I251 HydrophobicContact CD1-CG1 4.34Å; L177-I251 HydrophobicContact CD1-CG2 3.74Å; L177-I253 HydrophobicContact CB-CB 4.34Å; L177-I253 HydrophobicContact CB-CG2 4.21Å
178P97.7Very high95.9Very high1 Ų129.5 Ų29.51%0.00616%0.164CC..PPolyproline II helixtrans-70.6145177.328.6-34.5000112.7V121 A170 F171 A206V121-P178 HydrophobicContact CG1-CB 4.15Å; A170-P178 HydrophobicContact CB-CB 4.07Å; A170-P178 CarbonylContact O-C 3.56Å; A170-P178 VanDerWaalsContact O-CA 3.3Å; A170-P178 WeakPolarHBondContact O-CA 3.3Å; F171-P178 HydrophobicContact CD1-CB 4.27Å; F171-P178 HydrophobicContact CD1-CG 4.5Å; F171-P178 HydrophobicContact CD2-CB 4.32Å; F171-P178 HydrophobicContact CE1-CB 4.23Å; F171-P178 HydrophobicContact CE1-CG 4.14Å; F171-P178 HydrophobicContact CE2-CB 4.26Å; F171-P178 HydrophobicContact CG-CB 4.32Å; F171-P178 HydrophobicContact CZ-CB 4.23Å; F171-P178 HydrophobicContact CZ-CG 4.31Å; P178-A206 HydrophobicContact CG-CB 4.17Å
179Y97.4Very high95.3Very high21 Ų2136.2 Ų36.28%0.08219%0.187CC..PPolyproline II helixtrans-53.2144.9156.3-69.9-82.8000109.3V121 A170 T173 R181 V188 E198 I253V121-Y179 WeakPolarHBondContact CG2-O 3.2Å; A170-Y179 WeakPolarHBondContact O-CD2 3.41Å; A170-Y179 PolarHBondContact O-N 2.95Å; T173-Y179 HydrophobicContact CG2-CD2 3.78Å; T173-Y179 HydrophobicContact CG2-CE1 4.41Å; T173-Y179 HydrophobicContact CG2-CE2 3.56Å; T173-Y179 HydrophobicContact CG2-CG 4.27Å; Y179-R181 PolarHBondContact O-N 3.18Å; Y179-V188 HydrophobicContact CD2-CB 4.11Å; Y179-V188 HydrophobicContact CD2-CG1 4.05Å; Y179-V188 HydrophobicContact CD2-CG2 3.94Å; Y179-V188 HydrophobicContact CE2-CB 4.31Å; Y179-V188 HydrophobicContact CE2-CG2 3.9Å; Y179-V188 HydrophobicContact CG-CG1 4.42Å; Y179-E198 WeakPolarHBondContact CD1-O 3.11Å; Y179-I253 HydrophobicContact CD1-CD1 3.33Å; Y179-I253 HydrophobicContact CE1-CD1 3.57Å; Y179-I253 HydrophobicContact CG-CD1 3.91Å
180P95.6Very high94.6Very high27 Ų2736.3 Ų36.318%0.17520%0.196CC..SBendtrans-67-24.8178.429-36.7000112.8S120 V121 E198 D200S120-P180 WeakPolarHBondContact CA-O 3.42Å; V121-P180 PolarHBondContact N-O 2.69Å; P180-E198 HydrophobicContact CG-CB 3.84Å; P180-E198 HydrophobicContact CG-CG 4.19Å; P180-D200 WeakPolarHBondContact CG-O 3.46Å
181R96Very high93.9Very high67 Ų6742.5 Ų42.525%0.25324%0.237SC..EExtended strand (participates in β ladder)trans-128.2153.2-173.6-75174.7173.71234.2111.6D72 D75 V118 V119 Y179 T195 E198D72-R181 IonicContact OD1-CZ 3.36Å; D72-R181 IonicContact OD1-NH2 3.85Å; D72-R181 PolarHBondContact OD1-NH2 2.92Å; D75-R181 IonicContact OD1-NE 3.25Å; D75-R181 IonicContact OD2-CZ 2.73Å; D75-R181 IonicContact OD2-NE 2.73Å; D75-R181 PolarHBondContact OD2-NE 3.2Å; D75-R181 IonicContact OD2-NH2 3.43Å; D75-R181 PolarHBondContact OD2-NH2 2.95Å; V118-R181 HydrophobicContact CG1-CB 3.86Å; V118-R181 HydrophobicContact CG1-CG 4.18Å; V119-R181 CarbonylContact O-C 3.58Å; V119-R181 VanDerWaalsContact O-CA 3.3Å; V119-R181 WeakPolarHBondContact O-CA 3.27Å; Y179-R181 PolarHBondContact O-N 3.18Å; R181-T195 WeakPolarHBondContact CB-OG1 3.49Å; R181-E198 WeakPolarHBondContact CD-OE1 3.41Å
182I96.5Very high93.3Very high0 Ų048.1 Ų48.10%026%0.263CS..EExtended strand (participates in β ladder)trans-151.6146.1175.1-170.9152.3000111.4V118 V119 V121 R166 L167 P169 A170 V188V118-I182 CarbonylContact C-O 3.45Å; V118-I182 WeakPolarHBondContact CA-O 3.43Å; V119-I182 HydrophobicContact CG2-CG2 3.99Å; V119-I182 PolarHBondContact N-O 2.73Å; V119-I182 PolarHBondContact O-N 2.83Å; V121-I182 HydrophobicContact CG2-CB 3.81Å; V121-I182 HydrophobicContact CG2-CG2 3.54Å; R166-I182 WeakPolarHBondContact O-CD1 3.45Å; L167-I182 HydrophobicContact CD2-CG2 3.85Å; P169-I182 HydrophobicContact CB-CD1 4.05Å; P169-I182 HydrophobicContact CG-CD1 4.48Å; A170-I182 HydrophobicContact CB-CD1 4.02Å; I182-V188 HydrophobicContact CB-CG1 4.05Å; I182-V188 HydrophobicContact CD1-CG1 3.9Å; I182-V188 HydrophobicContact CG1-CG1 3.75Å
183N96.9Very high93Very high1 Ų144.5 Ų44.51%0.00524%0.244CC..EExtended strand (participates in β ladder)trans-85.1123167.9-175.6-54.2000110D116 I117 V118 K185 H186 G187 T193 T195D116-N183 PolarHBondContact OD1-ND2 2.86Å; I117-N183 WeakPolarHBondContact O-CA 3.35Å; V118-N183 HydrophobicContact CG2-CB 4.34Å; N183-K185 PolarHBondContact O-N 3.31Å; N183-K185 VanDerWaalsContact O-N 3.08Å; N183-K185 PolarHBondContact OD1-N 3.13Å; N183-H186 HydrophobicContact CB-CB 4.31Å; N183-H186 PolarHBondContact OD1-N 2.91Å; N183-G187 WeakPolarHBondContact CB-O 3.33Å; N183-G187 PolarHBondContact N-O 3.31Å; N183-G187 VanDerWaalsContact O-CA 3.29Å; N183-G187 WeakPolarHBondContact O-CA 3.2Å; N183-G187 PolarHBondContact O-N 3.41Å; N183-T193 WeakPolarHBondContact CB-O 3.27Å; N183-T193 PolarHBondContact ND2-O 2.84Å; N183-T195 HydrophobicContact CB-CG2 4.37Å
184L94.9Very high92.7Very high3 Ų350.7 Ų50.72%0.01627%0.265CS..THydrogen-bonded Turntrans-61.8-19.8-175.1-74.3180000114.8F80 I117 V119 L163 R166F80-L184 HydrophobicContact CD1-CD1 4.02Å; F80-L184 HydrophobicContact CE1-CD1 4.07Å; I117-L184 HydrophobicContact CG2-CD1 3.98Å; I117-L184 HydrophobicContact CG2-CG 4.45Å; I117-L184 PolarHBondContact O-N 3Å; V119-L184 HydrophobicContact CG1-CD1 4.03Å; V119-L184 HydrophobicContact CG1-CG 4.2Å; V119-L184 HydrophobicContact CG2-CD1 4.31Å; V119-L184 HydrophobicContact CG2-CD2 3.75Å; V119-L184 HydrophobicContact CG2-CG 3.75Å; L163-L184 HydrophobicContact CD1-CD2 4.05Å; R166-L184 WeakPolarHBondContact CD-O 3.44Å; R166-L184 PolarHBondContact NH1-O 2.89Å
185K94.7Very high92.5Very high116 Ų11646.4 Ų46.450%0.50424%0.235SC..THydrogen-bonded Turntrans-110.1-38.3-179-178.3-173167.7-151.90113.3D114 N115 D116 N183D114-K185 WeakPolarHBondContact O-CB 3.17Å; D114-K185 WeakPolarHBondContact O-CD 3.34Å; N115-K185 WeakPolarHBondContact O-CB 3.42Å; D116-K185 HydrophobicContact CB-CD 4Å; N183-K185 PolarHBondContact O-N 3.31Å; N183-K185 VanDerWaalsContact O-N 3.08Å; N183-K185 PolarHBondContact OD1-N 3.13Å
186H94.5Very high92Very high49 Ų4946.5 Ų46.523%0.22724%0.239CC..THydrogen-bonded Turntrans-105.8-10.1-174.1-60.9-102000113.6D116 N183 E192 T193D116-H186 IonicContact OD1-CD2 3.26Å; D116-H186 PolarHBondContact OD1-CD2 3.12Å; D116-H186 IonicContact OD1-NE2 3.58Å; N183-H186 HydrophobicContact CB-CB 4.31Å; N183-H186 PolarHBondContact OD1-N 2.91Å; H186-E192 HydrophobicContact CB-CB 4.46Å; H186-E192 IonicContact CE1-OE2 3.04Å; H186-E192 PolarHBondContact CE1-OE2 3.39Å; H186-E192 IonicContact ND1-OE2 3.22Å; H186-E192 PolarHBondContact ND1-OE2 3.41Å; H186-T193 HydrophobicContact CB-CG2 3.8Å; H186-T193 VanDerWaalsContact O-CG2 3.27Å; H186-T193 WeakPolarHBondContact O-CG2 3.25Å
187G94Very high91.6Very high12 Ų1251.9 Ų51.912%0.12427%0.269CS..BIsolated β-bridgetrans76.5-137.9178.500000114.1N183 T193N183-G187 WeakPolarHBondContact CB-O 3.33Å; N183-G187 PolarHBondContact N-O 3.31Å; N183-G187 VanDerWaalsContact O-CA 3.29Å; N183-G187 WeakPolarHBondContact O-CA 3.2Å; N183-G187 PolarHBondContact O-N 3.41Å; G187-T193 WeakPolarHBondContact O-CB 3.24Å; G187-T193 WeakPolarHBondContact O-CG2 3.32Å
188V92.2Very high91.3Very high10 Ų1053.7 Ų53.76%0.06128%0.277CS..THydrogen-bonded Turntrans-12215.1-179.3-59.10000113.6P169 Y179 I182P169-V188 HydrophobicContact CB-CG2 4.26Å; P169-V188 VanDerWaalsContact O-CG2 3.26Å; P169-V188 WeakPolarHBondContact O-CG2 3.39Å; Y179-V188 HydrophobicContact CD2-CB 4.11Å; Y179-V188 HydrophobicContact CD2-CG1 4.05Å; Y179-V188 HydrophobicContact CD2-CG2 3.94Å; Y179-V188 HydrophobicContact CE2-CB 4.31Å; Y179-V188 HydrophobicContact CE2-CG2 3.9Å; Y179-V188 HydrophobicContact CG-CG1 4.42Å; I182-V188 HydrophobicContact CB-CG1 4.05Å; I182-V188 HydrophobicContact CD1-CG1 3.9Å; I182-V188 HydrophobicContact CG1-CG1 3.75Å
189R85.9Confident91.1Very high169 Ų16957 Ų5764%0.63830%0.297SS*.SBendtrans-136110.6179.4-68.3-173.8176.8172.12.8112.5N172N172-R189 PolarHBondContact ND2-NH2 2.94Å; N172-R189 PolarHBondContact OD1-NH2 2.75Å
190G82.6Confident91Very high48 Ų4858.3 Ų58.350%0.49531%0.306SS..SBendtrans145.1171.6173.500000111.1E192 T193G190-E192 VanDerWaalsContact C-N 3.31Å; G190-T193 PolarHBondContact O-OG1 3.49Å; G190-T193 VanDerWaalsContact O-OG1 3.06Å
191P82Confident91.1Very high131 Ų13157.3 Ų57.385%0.85130%0.299SS*.SBendtrans-70.9-29.1172.128.8-33000112.2T193P191-T193 VanDerWaalsContact C-N 3.32Å; P191-T193 PolarHBondContact O-N 3.09Å
192E84.9Confident91.1Very high125 Ų12555.3 Ų55.358%0.58430%0.295SS*.THydrogen-bonded Turntrans-73.9-19.6-175.7-59.8176153.700113.6H186 G190 R194H186-E192 HydrophobicContact CB-CB 4.46Å; H186-E192 IonicContact CE1-OE2 3.04Å; H186-E192 PolarHBondContact CE1-OE2 3.39Å; H186-E192 IonicContact ND1-OE2 3.22Å; H186-E192 PolarHBondContact ND1-OE2 3.41Å; G190-E192 VanDerWaalsContact C-N 3.31Å; E192-R194 VanDerWaalsContact C-N 3.35Å; E192-R194 PolarHBondContact O-N 3.01Å
193T87.8Confident91.1Very high5 Ų555.3 Ų55.33%0.03130%0.295CS..THydrogen-bonded Turntrans-67.4-34.8-173.4550000112.9V118 N183 H186 G187 G190 P191 T195V118-T193 WeakPolarHBondContact CG2-O 3.46Å; N183-T193 WeakPolarHBondContact CB-O 3.27Å; N183-T193 PolarHBondContact ND2-O 2.84Å; H186-T193 HydrophobicContact CB-CG2 3.8Å; H186-T193 VanDerWaalsContact O-CG2 3.27Å; H186-T193 WeakPolarHBondContact O-CG2 3.25Å; G187-T193 WeakPolarHBondContact O-CB 3.24Å; G187-T193 WeakPolarHBondContact O-CG2 3.32Å; G190-T193 PolarHBondContact O-OG1 3.49Å; G190-T193 VanDerWaalsContact O-OG1 3.06Å; P191-T193 VanDerWaalsContact C-N 3.32Å; P191-T193 PolarHBondContact O-N 3.09Å; T193-T195 WeakPolarHBondContact CB-O 3.33Å; T193-T195 PolarHBondContact O-N 3.06Å; T193-T195 PolarHBondContact OG1-O 2.85Å
194R89.6Confident91.1Very high151 Ų15155.3 Ų55.357%0.5730%0.295SS*.SBendtrans60.519.3-173.4-56.9166.8-79.6156.6-3.8113.5D116 V118 E192D116-R194 PolarHBondContact O-NH2 2.88Å; D116-R194 IonicContact OD1-CZ 2.7Å; D116-R194 IonicContact OD1-NH2 3.03Å; D116-R194 PolarHBondContact OD1-NH2 3.47Å; D116-R194 IonicContact OD2-NH2 3.32Å; D116-R194 PolarHBondContact OD2-NH2 2.92Å; V118-R194 HydrophobicContact CG2-CB 4.08Å; E192-R194 VanDerWaalsContact C-N 3.35Å; E192-R194 PolarHBondContact O-N 3.01Å
195T90.3Very high91.2Very high6 Ų656.3 Ų56.34%0.03730%0.302CS..  trans-162.7164.7179.3-176.70000109.7V118 R181 N183 T193 E198V118-T195 HydrophobicContact CG1-CG2 3.99Å; V118-T195 HydrophobicContact CG2-CG2 3.98Å; R181-T195 WeakPolarHBondContact CB-OG1 3.49Å; N183-T195 HydrophobicContact CB-CG2 4.37Å; T193-T195 WeakPolarHBondContact CB-O 3.33Å; T193-T195 PolarHBondContact O-N 3.06Å; T193-T195 PolarHBondContact OG1-O 2.85Å; T195-E198 WeakPolarHBondContact CB-OE1 3.38Å; T195-E198 VanDerWaalsContact OG1-CD 3.24Å; T195-E198 PolarHBondContact OG1-OE1 2.89Å; T195-E198 PolarHBondContact OG1-OE2 3.08Å
196G84.4Confident91.3Very high20 Ų2050.8 Ų50.821%0.20628%0.279CS..SBendtrans106.914-171.700000113.7E198G196-E198 PolarHBondContact N-OE2 3.49Å
197T88.2Confident91.4Very high128 Ų12848.5 Ų48.579%0.78527%0.268SS*.  trans-112.5-12174.850.60000112.7T199T197-T199 PolarHBondContact O-N 3.37Å
198E91.5Very high91.6Very high38 Ų3848 Ų4818%0.17826%0.263CS..  trans-64.2119.3176.6-59.890144.900109.7Y179 P180 R181 T195 G196 I253Y179-E198 WeakPolarHBondContact CD1-O 3.11Å; P180-E198 HydrophobicContact CG-CB 3.84Å; P180-E198 HydrophobicContact CG-CG 4.19Å; R181-E198 WeakPolarHBondContact CD-OE1 3.41Å; T195-E198 WeakPolarHBondContact CB-OE1 3.38Å; T195-E198 VanDerWaalsContact OG1-CD 3.24Å; T195-E198 PolarHBondContact OG1-OE1 2.89Å; T195-E198 PolarHBondContact OG1-OE2 3.08Å; G196-E198 PolarHBondContact N-OE2 3.49Å; E198-I253 WeakPolarHBondContact O-CD1 3.19Å
199T94.1Very high91.9Very high69 Ų6947.5 Ų47.542%0.42326%0.26SS..  trans-90.2-10.8-177.363.90000113.8T197 N252 I253T197-T199 PolarHBondContact O-N 3.37Å; T199-N252 WeakPolarHBondContact CB-ND2 3.07Å; T199-N252 CarbonylContact O-C 3.53Å; T199-N252 VanDerWaalsContact O-CA 3.28Å; T199-N252 WeakPolarHBondContact O-CA 3.44Å; T199-N252 VanDerWaalsContact O-CG 3.31Å; T199-N252 PolarHBondContact O-ND2 3.4Å; T199-N252 VanDerWaalsContact O-ND2 3.12Å; T199-N252 PolarHBondContact OG1-ND2 3.25Å; T199-I253 WeakPolarHBondContact O-CG1 3.34Å; T199-I253 PolarHBondContact O-N 2.89Å
200D95.2Very high92.5Very high50 Ų5039.5 Ų39.527%0.26723%0.23SC..EExtended strand (participates in β ladder)trans-131.4147.2-163.3-63.6-1.6000110.9P180 T250 I251 N252P180-D200 WeakPolarHBondContact CG-O 3.46Å; D200-T250 HydrophobicContact CB-CG2 4.08Å; D200-I251 WeakPolarHBondContact CA-O 3.26Å; D200-N252 PolarHBondContact OD1-ND2 3.49Å
201T96.1Very high93.2Very high5 Ų537.2 Ų37.23%0.03121%0.206CC..EExtended strand (participates in β ladder)trans-143.5160.4177.7-163.80000110.8C205 A206 T250 I251 I253T201-C205 WeakPolarHBondContact OG1-CB 3.46Å; T201-A206 HydrophobicContact CG2-CB 3.86Å; T201-T250 WeakPolarHBondContact O-CA 3.23Å; T201-T250 WeakPolarHBondContact O-CG2 3.49Å; T201-I251 HydrophobicContact CG2-CG2 3.93Å; T201-I251 PolarHBondContact N-O 3.16Å; T201-I251 PolarHBondContact O-N 2.87Å; T201-I253 HydrophobicContact CG2-CG2 3.44Å; T201-I253 VanDerWaalsContact CG2-CG2 3.44Å
202C95.9Very high94Very high25 Ų2531 Ų3117%0.16917%0.166CC..EExtended strand (participates in β ladder)trans-84.2158.3176.188.20000112.4C205 A206 T249C202-C205 HydrophobicContact CB-CB 4.01Å; C202-C205 WeakPolarHBondContact CB-SG 3.46Å; C202-C205 VanDerWaalsContact O-CB 3.3Å; C202-C205 WeakPolarHBondContact O-CB 3.39Å; C202-C205 PolarHBondContact O-N 3Å; C202-C205 WeakPolarHBondContact SG-CB 3.33Å; C202-C205 PolarHBondContact SG-N 3.18Å; C202-C205 CovalentContact SG-SG 2.05Å; C202-C205 PolarHBondContact SG-SG 3.25Å; C202-A206 PolarHBondContact O-N 3.35Å; C202-A206 VanDerWaalsContact O-N 3.09Å; C202-T249 VanDerWaalsContact CA-O 3.29Å; C202-T249 WeakPolarHBondContact CA-O 3.09Å
203T97.9Very high94.7Very high0 Ų025 Ų250%014%0.138CC..Hα-helixtrans-67.7-40.1-176-66.40000112.3G207 V247 G248 T249 W258 G268 I269 Y272T203-G207 PolarHBondContact O-N 2.92Å; T203-V247 HydrophobicContact CG2-CB 4.4Å; T203-V247 HydrophobicContact CG2-CG2 4.01Å; T203-G248 PolarHBondContact OG1-O 3.38Å; T203-T249 PolarHBondContact N-O 2.97Å; T203-T249 VanDerWaalsContact N-O 3.12Å; T203-W258 WeakPolarHBondContact OG1-CZ3 3.43Å; T203-G268 PolarHBondContact N-O 3.07Å; T203-I269 HydrophobicContact CG2-CG2 4.15Å; T203-Y272 HydrophobicContact CG2-CD1 3.85Å; T203-Y272 HydrophobicContact CG2-CD2 4.42Å; T203-Y272 HydrophobicContact CG2-CE1 4.44Å; T203-Y272 HydrophobicContact CG2-CG 3.84Å
204A97.3Very high95.1Very high1 Ų124.8 Ų24.81%0.00814%0.136CC..Hα-helixtrans-58.7-50.1167.200000111.3F122 A206 G207 T208 G268 D270 S271F122-A204 HydrophobicContact CE2-CB 4.28Å; A204-A206 PolarHBondContact O-N 3.19Å; A204-G207 PolarHBondContact O-N 3.18Å; A204-T208 VanDerWaalsContact O-CB 3.27Å; A204-T208 WeakPolarHBondContact O-CB 3.25Å; A204-T208 PolarHBondContact O-N 3.1Å; A204-T208 PolarHBondContact O-OG1 3.19Å; A204-G268 PolarHBondContact N-O 3.33Å; A204-D270 VanDerWaalsContact CB-OD1 3.23Å; A204-D270 WeakPolarHBondContact CB-OD1 3.39Å; A204-S271 WeakPolarHBondContact CB-OG 3.4Å
205C96.4Very high95.5Very high24 Ų2417.6 Ų17.616%0.16211%0.109CC..Hα-helixtrans-52.7-34.9-178.2-550000113.7F122 T201 C202F122-C205 HydrophobicContact CB-CB 4.26Å; T201-C205 WeakPolarHBondContact OG1-CB 3.46Å; C202-C205 HydrophobicContact CB-CB 4.01Å; C202-C205 WeakPolarHBondContact CB-SG 3.46Å; C202-C205 VanDerWaalsContact O-CB 3.3Å; C202-C205 WeakPolarHBondContact O-CB 3.39Å; C202-C205 PolarHBondContact O-N 3Å; C202-C205 WeakPolarHBondContact SG-CB 3.33Å; C202-C205 PolarHBondContact SG-N 3.18Å; C202-C205 CovalentContact SG-SG 2.05Å; C202-C205 PolarHBondContact SG-SG 3.25Å
206A96.6Very high95.9Very high1 Ų117.3 Ų17.31%0.00811%0.108CC..Hα-helixtrans-98.1-19.6178.100000114.6L177 P178 T201 C202 A204 L236L177-A206 HydrophobicContact CB-CB 4.36Å; L177-A206 HydrophobicContact CD2-CB 4.03Å; P178-A206 HydrophobicContact CG-CB 4.17Å; T201-A206 HydrophobicContact CG2-CB 3.86Å; C202-A206 PolarHBondContact O-N 3.35Å; C202-A206 VanDerWaalsContact O-N 3.09Å; A204-A206 PolarHBondContact O-N 3.19Å; A206-L236 HydrophobicContact CB-CD1 4.15Å
207G97Very high96.5Very high1 Ų116.7 Ų16.71%0.0110%0.1CC..Hα-helixtrans-91-32.4-178.400000114.3T203 A204 M209T203-G207 PolarHBondContact O-N 2.92Å; A204-G207 PolarHBondContact O-N 3.18Å; G207-M209 PolarHBondContact O-N 3.12Å
208T98.4Very high96.9Very high0 Ų012.3 Ų12.30%07%0.069CC..THydrogen-bonded Turntrans-91.652.2-167.5-47.20000111.4F122 N125 I126 A204 S271 Y272 Y275 T468F122-T208 HydrophobicContact CE2-CG2 3.95Å; N125-T208 PolarHBondContact ND2-O 3.3Å; I126-T208 HydrophobicContact CG2-CG2 3.87Å; A204-T208 VanDerWaalsContact O-CB 3.27Å; A204-T208 WeakPolarHBondContact O-CB 3.25Å; A204-T208 PolarHBondContact O-N 3.1Å; A204-T208 PolarHBondContact O-OG1 3.19Å; T208-S271 WeakPolarHBondContact CG2-OG 3.27Å; T208-S271 VanDerWaalsContact OG1-C 3.31Å; T208-S271 WeakPolarHBondContact OG1-CB 3.5Å; T208-S271 PolarHBondContact OG1-OG 3.02Å; T208-Y272 PolarHBondContact OG1-N 3.12Å; T208-Y275 HydrophobicContact CG2-CD1 3.94Å; T208-Y275 HydrophobicContact CG2-CD2 3.73Å; T208-Y275 HydrophobicContact CG2-CE1 3.67Å; T208-Y275 HydrophobicContact CG2-CE2 3.42Å; T208-Y275 VanDerWaalsContact CG2-CE2 3.42Å; T208-Y275 HydrophobicContact CG2-CG 3.99Å; T208-T468 HydrophobicContact CG2-CG2 3.92Å
209M98.3Very high97.1Very high1 Ų113 Ų131%0.0057%0.072CC..THydrogen-bonded Turntrans-122.6-17.9-179.6-54.2-64.6-70.200112.6V121 N125 F171 G207 F213 A229V121-M209 HydrophobicContact CG1-CE 3.69Å; V121-M209 HydrophobicContact CG1-SD 4.42Å; N125-M209 HydrophobicContact CB-CE 3.65Å; N125-M209 HydrophobicContact CB-SD 3.67Å; F171-M209 HydrophobicContact CE2-CE 4.02Å; F171-M209 HydrophobicContact CZ-CB 4.28Å; F171-M209 HydrophobicContact CZ-CE 3.75Å; F171-M209 HydrophobicContact CZ-CG 4.07Å; G207-M209 PolarHBondContact O-N 3.12Å; M209-F213 HydrophobicContact CE-CE1 3.8Å; M209-F213 HydrophobicContact CE-CE2 4.46Å; M209-F213 HydrophobicContact CE-CZ 3.77Å; M209-F213 VanDerWaalsContact O-CB 3.23Å; M209-F213 WeakPolarHBondContact O-CB 3.47Å; M209-F213 PolarHBondContact O-N 3.36Å; M209-F213 VanDerWaalsContact O-N 3.13Å; M209-A229 HydrophobicContact CB-CB 3.95Å
210I98Very high97.2Very high1 Ų111.5 Ų11.51%0.0056%0.062CC..Hα-helixtrans-73.3-32.7-164.9-172.360.7000114.2A214 E226 A229 R230 L233 Y275 A279 L283 F288I210-A214 HydrophobicContact CD1-CB 4.42Å; I210-A214 WeakPolarHBondContact O-CB 3.49Å; I210-A214 PolarHBondContact O-N 2.9Å; I210-E226 HydrophobicContact CD1-CG 3.94Å; I210-A229 HydrophobicContact CB-CB 4.25Å; I210-A229 HydrophobicContact CD1-CB 3.89Å; I210-R230 HydrophobicContact CD1-CB 4.3Å; I210-L233 HydrophobicContact CB-CD1 3.63Å; I210-L233 HydrophobicContact CG1-CD1 4.01Å; I210-L233 HydrophobicContact CG2-CD1 3.57Å; I210-Y275 HydrophobicContact CG2-CD2 3.86Å; I210-Y275 HydrophobicContact CG2-CG 4.36Å; I210-A279 HydrophobicContact CG1-CB 4.33Å; I210-A279 HydrophobicContact CG2-CB 3.91Å; I210-L283 HydrophobicContact CG1-CD1 4.45Å; I210-F288 HydrophobicContact CD1-CZ 4.43Å; I210-F288 HydrophobicContact CG1-CZ 4.11Å
211L98.3Very high97.2Very high0 Ų011.9 Ų11.90%08%0.078CC..Hα-helixtrans-68.8-47.8-176.9-62-174.9000111.1A215 Y275 K278 A279 L282 T467 L473L211-A215 WeakPolarHBondContact O-CB 3.44Å; L211-A215 PolarHBondContact O-N 3.33Å; L211-Y275 HydrophobicContact CB-CD2 4.29Å; L211-Y275 HydrophobicContact CB-CE2 3.83Å; L211-Y275 HydrophobicContact CD1-CD1 3.82Å; L211-Y275 HydrophobicContact CD1-CD2 4.15Å; L211-Y275 HydrophobicContact CD1-CE1 3.49Å; L211-Y275 VanDerWaalsContact CD1-CE1 3.49Å; L211-Y275 HydrophobicContact CD1-CE2 3.86Å; L211-Y275 HydrophobicContact CD1-CG 4.13Å; L211-Y275 HydrophobicContact CG-CD1 4.22Å; L211-Y275 HydrophobicContact CG-CD2 3.7Å; L211-Y275 HydrophobicContact CG-CE1 4.14Å; L211-Y275 HydrophobicContact CG-CE2 3.61Å; L211-Y275 HydrophobicContact CG-CG 4Å; L211-K278 HydrophobicContact CD1-CB 3.82Å; L211-K278 HydrophobicContact CD1-CD 4.23Å; L211-K278 HydrophobicContact CD2-CB 4.09Å; L211-A279 HydrophobicContact CD2-CB 4.03Å; L211-L282 HydrophobicContact CB-CD2 4.38Å; L211-L282 HydrophobicContact CD2-CB 4.35Å; L211-L282 HydrophobicContact CD2-CD2 3.89Å; L211-T467 HydrophobicContact CB-CG2 4.49Å; L211-T467 HydrophobicContact CD1-CG2 4.39Å; L211-L473 HydrophobicContact CB-CD1 3.92Å
212E98.7Very high97.1Very high0 Ų013.9 Ų13.90%09%0.088CC..Hα-helixtrans-72.1-44.3-178-55.370.6-151.400110.4N125 L129 L133 A215 L216 Y275 T467N125-E212 VanDerWaalsContact ND2-CD 3.28Å; N125-E212 PolarHBondContact ND2-OE2 2.92Å; L129-E212 HydrophobicContact CD2-CB 3.93Å; L129-E212 HydrophobicContact CG-CB 4.07Å; L133-E212 HydrophobicContact CD1-CB 4.01Å; L133-E212 VanDerWaalsContact CD1-O 3.32Å; L133-E212 WeakPolarHBondContact CD1-O 3.2Å; E212-A215 PolarHBondContact O-N 2.93Å; E212-L216 VanDerWaalsContact O-CB 3.23Å; E212-L216 WeakPolarHBondContact O-CB 3.4Å; E212-L216 PolarHBondContact O-N 2.87Å; E212-Y275 PolarHBondContact OE1-OH 3.1Å; E212-Y275 WeakPolarHBondContact OE2-CE2 3.33Å; E212-T467 WeakPolarHBondContact OE1-CG2 3.45Å
213F98.6Very high97.2Very high0 Ų014.7 Ų14.70%09%0.093CC..Hα-helixtrans-69.1-37.3179.1-81.735.6000111.5N125 L129 L167 L168 F171 M209 S217 F225 A229N125-F213 VanDerWaalsContact OD1-CD1 3.27Å; N125-F213 WeakPolarHBondContact OD1-CD1 3.36Å; N125-F213 WeakPolarHBondContact OD1-CE1 3.44Å; L129-F213 HydrophobicContact CD2-CD1 3.68Å; L129-F213 HydrophobicContact CD2-CE1 3.61Å; L167-F213 HydrophobicContact CB-CZ 4.01Å; L167-F213 HydrophobicContact CD1-CE1 4.26Å; L167-F213 HydrophobicContact CD1-CZ 4.38Å; L168-F213 HydrophobicContact CD2-CE2 4.28Å; F171-F213 HydrophobicContact CD2-CE2 4.36Å; F171-F213 HydrophobicContact CE2-CD2 4.42Å; F171-F213 AromaticContact CE2-CE2 3.43Å; F171-F213 HydrophobicContact CE2-CE2 3.43Å; F171-F213 VanDerWaalsContact CE2-CE2 3.43Å; F171-F213 AromaticContact CE2-CZ 3.79Å; F171-F213 HydrophobicContact CE2-CZ 3.79Å; F171-F213 HydrophobicContact CZ-CD2 4.24Å; F171-F213 AromaticContact CZ-CE2 3.64Å; F171-F213 HydrophobicContact CZ-CE2 3.64Å; F171-F213 HydrophobicContact CZ-CZ 4.15Å; M209-F213 HydrophobicContact CE-CE1 3.8Å; M209-F213 HydrophobicContact CE-CE2 4.46Å; M209-F213 HydrophobicContact CE-CZ 3.77Å; M209-F213 VanDerWaalsContact O-CB 3.23Å; M209-F213 WeakPolarHBondContact O-CB 3.47Å; M209-F213 PolarHBondContact O-N 3.36Å; M209-F213 VanDerWaalsContact O-N 3.13Å; F213-S217 WeakPolarHBondContact O-CB 3.42Å; F213-S217 PolarHBondContact O-N 3.45Å; F213-S217 PolarHBondContact O-OG 3.45Å; F213-F225 HydrophobicContact CB-CB 3.8Å; F213-F225 HydrophobicContact CD2-CB 3.83Å; F213-F225 WeakPolarHBondContact CD2-O 3.35Å; F213-F225 HydrophobicContact CG-CB 3.94Å; F213-F225 WeakPolarHBondContact O-CB 3.36Å; F213-A229 HydrophobicContact CB-CB 3.88Å; F213-A229 HydrophobicContact CD2-CB 4.13Å; F213-A229 HydrophobicContact CG-CB 4.25Å
214A97.4Very high97.1Very high0 Ų016.7 Ų16.70%011%0.105CC..Hα-helixtrans-66.7-48.1172.400000111.4I210 L216 S217 R218 E226 L283I210-A214 HydrophobicContact CD1-CB 4.42Å; I210-A214 WeakPolarHBondContact O-CB 3.49Å; I210-A214 PolarHBondContact O-N 2.9Å; A214-L216 PolarHBondContact O-N 2.94Å; A214-S217 CarbonylContact O-C 3.57Å; A214-S217 WeakPolarHBondContact O-CA 3.44Å; A214-S217 WeakPolarHBondContact O-CB 3.25Å; A214-S217 PolarHBondContact O-N 3.11Å; A214-R218 WeakPolarHBondContact O-CG 3.44Å; A214-R218 PolarHBondContact O-N 3.43Å; A214-E226 HydrophobicContact CB-CB 4.38Å; A214-E226 HydrophobicContact CB-CG 3.87Å; A214-L283 HydrophobicContact CB-CD1 3.86Å; A214-L283 HydrophobicContact CB-CD2 3.82Å; A214-L283 HydrophobicContact CB-CG 4.43Å
215A97.7Very high97.2Very high0 Ų016.6 Ų16.60%011%0.105CC..Hα-helixtrans-58.3-45.5177.500000111.9L133 L211 E212 S217 R218 F219 L473 L477L133-A215 HydrophobicContact CD1-CB 4.26Å; L211-A215 WeakPolarHBondContact O-CB 3.44Å; L211-A215 PolarHBondContact O-N 3.33Å; E212-A215 PolarHBondContact O-N 2.93Å; A215-S217 VanDerWaalsContact C-N 3.31Å; A215-S217 PolarHBondContact O-N 3.25Å; A215-R218 PolarHBondContact O-N 2.94Å; A215-R218 VanDerWaalsContact O-N 3.12Å; A215-F219 HydrophobicContact CB-CD2 4.34Å; A215-F219 HydrophobicContact CB-CE2 4.23Å; A215-F219 WeakPolarHBondContact O-CD2 3.38Å; A215-F219 PolarHBondContact O-N 2.86Å; A215-L473 HydrophobicContact CB-CD1 4.1Å; A215-L473 HydrophobicContact CB-CD2 3.97Å; A215-L477 HydrophobicContact CB-CD1 3.85Å
216L98.3Very high97.2Very high0 Ų015.9 Ų15.90%010%0.099CC..Hα-helixtrans-58.2-41.8173.4-17765.1000111.8L129 L133 L157 A160 K161 E212 A214 T220 F225L129-L216 HydrophobicContact CD1-CD2 4.22Å; L129-L216 HydrophobicContact CD2-CD2 4.29Å; L133-L216 HydrophobicContact CD1-CB 4.27Å; L133-L216 HydrophobicContact CD2-CB 4.36Å; L133-L216 HydrophobicContact CD2-CD1 4.18Å; L157-L216 HydrophobicContact CD1-CD1 4.1Å; A160-L216 HydrophobicContact CB-CD1 3.94Å; K161-L216 HydrophobicContact CB-CD1 4.28Å; E212-L216 VanDerWaalsContact O-CB 3.23Å; E212-L216 WeakPolarHBondContact O-CB 3.4Å; E212-L216 PolarHBondContact O-N 2.87Å; A214-L216 PolarHBondContact O-N 2.94Å; L216-T220 HydrophobicContact CD1-CG2 3.7Å; L216-T220 HydrophobicContact CG-CG2 4.34Å; L216-T220 WeakPolarHBondContact O-CB 3.33Å; L216-T220 VanDerWaalsContact O-CG2 3.29Å; L216-T220 WeakPolarHBondContact O-CG2 3.39Å; L216-T220 PolarHBondContact O-N 3.12Å; L216-T220 PolarHBondContact O-OG1 3.33Å; L216-F225 HydrophobicContact CB-CD2 4.38Å; L216-F225 HydrophobicContact CD2-CB 4.43Å; L216-F225 HydrophobicContact CD2-CD1 3.81Å; L216-F225 HydrophobicContact CD2-CD2 3.63Å; L216-F225 HydrophobicContact CD2-CE1 3.91Å; L216-F225 HydrophobicContact CD2-CE2 3.73Å; L216-F225 HydrophobicContact CD2-CG 3.68Å; L216-F225 HydrophobicContact CD2-CZ 3.87Å; L216-F225 HydrophobicContact CG-CD2 3.75Å; L216-F225 HydrophobicContact CG-CE2 3.89Å; L216-F225 HydrophobicContact CG-CG 4.22Å; L216-F225 HydrophobicContact CG-CZ 4.49Å
217S97.6Very high97.3Very high6 Ų618.8 Ų18.84%0.04212%0.115CC..Hα-helixtrans-62.7-40.4173.7-770000113.1F213 A214 A215 G221 D222 E226F213-S217 WeakPolarHBondContact O-CB 3.42Å; F213-S217 PolarHBondContact O-N 3.45Å; F213-S217 PolarHBondContact O-OG 3.45Å; A214-S217 CarbonylContact O-C 3.57Å; A214-S217 WeakPolarHBondContact O-CA 3.44Å; A214-S217 WeakPolarHBondContact O-CB 3.25Å; A214-S217 PolarHBondContact O-N 3.11Å; A215-S217 VanDerWaalsContact C-N 3.31Å; A215-S217 PolarHBondContact O-N 3.25Å; S217-G221 CarbonylContact O-C 3.5Å; S217-G221 WeakPolarHBondContact O-CA 3.49Å; S217-G221 PolarHBondContact O-N 3.06Å; S217-D222 VanDerWaalsContact CA-O 3.27Å; S217-D222 WeakPolarHBondContact CA-O 3.45Å; S217-D222 WeakPolarHBondContact CB-O 3.41Å; S217-D222 PolarHBondContact O-N 2.8Å; S217-D222 PolarHBondContact OG-O 3.29Å; S217-E226 PolarHBondContact OG-N 3.35Å
218R95.1Very high97.3Very high37 Ų3720.9 Ų20.914%0.1412%0.124CC..Hα-helixtrans-69.1-46.3177.4-59.9-45.5161.5145.3-13.5112.6A214 A215 E226 L477 A480 N482A214-R218 WeakPolarHBondContact O-CG 3.44Å; A214-R218 PolarHBondContact O-N 3.43Å; A215-R218 PolarHBondContact O-N 2.94Å; A215-R218 VanDerWaalsContact O-N 3.12Å; R218-E226 IonicContact CZ-OE2 3.33Å; R218-E226 IonicContact NE-OE2 2.7Å; R218-E226 PolarHBondContact NE-OE2 3.38Å; R218-E226 IonicContact NH2-OE1 2.82Å; R218-E226 PolarHBondContact NH2-OE1 3.04Å; R218-E226 IonicContact NH2-OE2 3.34Å; R218-E226 PolarHBondContact NH2-OE2 3.23Å; R218-L477 HydrophobicContact CB-CB 4.43Å; R218-L477 HydrophobicContact CB-CD2 3.79Å; R218-L477 HydrophobicContact CG-CB 4.28Å; R218-A480 HydrophobicContact CB-CB 4.09Å; R218-A480 HydrophobicContact CG-CB 4.3Å; R218-A480 PolarHBondContact NH1-O 2.85Å; R218-N482 PolarHBondContact NH1-OD1 3.34Å; R218-N482 PolarHBondContact NH2-OD1 3.07Å
219F95.7Very high97.3Very high53 Ų5321 Ų2123%0.23213%0.125CC..Hα-helixtrans-68-38179.2-72.5-61.8000112.7L133 H136 S137 L157 A215 P474 L477L133-F219 HydrophobicContact CD2-CD2 3.94Å; L133-F219 HydrophobicContact CD2-CE2 4.38Å; H136-F219 AromaticContact CD2-CD1 3.89Å; H136-F219 AromaticContact CD2-CG 3.94Å; H136-F219 AromaticContact NE2-CD1 3.59Å; H136-F219 AromaticContact NE2-CE1 3.98Å; H136-F219 AromaticContact NE2-CG 3.95Å; S137-F219 WeakPolarHBondContact OG-CZ 3.18Å; L157-F219 HydrophobicContact CD1-CB 3.48Å; L157-F219 VanDerWaalsContact CD1-CB 3.48Å; L157-F219 HydrophobicContact CD1-CG 4.25Å; L157-F219 HydrophobicContact CD2-CB 3.88Å; L157-F219 HydrophobicContact CG-CB 4.34Å; A215-F219 HydrophobicContact CB-CD2 4.34Å; A215-F219 HydrophobicContact CB-CE2 4.23Å; A215-F219 WeakPolarHBondContact O-CD2 3.38Å; A215-F219 PolarHBondContact O-N 2.86Å; F219-P474 HydrophobicContact CZ-CG 4.04Å; F219-L477 HydrophobicContact CD1-CD2 4.1Å; F219-L477 HydrophobicContact CD2-CD2 4.4Å; F219-L477 HydrophobicContact CE1-CD2 3.8Å; F219-L477 HydrophobicContact CE2-CD1 3.87Å; F219-L477 HydrophobicContact CE2-CD2 4.13Å; F219-L477 HydrophobicContact CG-CD2 4.38Å; F219-L477 HydrophobicContact CZ-CD1 3.96Å; F219-L477 HydrophobicContact CZ-CD2 3.81Å; F219-L477 HydrophobicContact CZ-CG 4.36Å
220T96.4Very high97.3Very high36 Ų3623.3 Ų23.322%0.22113%0.133CC..Hα-helixtrans-92.9-9.4-177.368.30000114.7L157 K161 L216 D222L157-T220 HydrophobicContact CD1-CG2 3.73Å; L157-T220 HydrophobicContact CD2-CG2 4.24Å; L157-T220 HydrophobicContact CG-CG2 3.97Å; K161-T220 HydrophobicContact CB-CG2 4.17Å; K161-T220 HydrophobicContact CD-CG2 3.9Å; K161-T220 HydrophobicContact CG-CG2 4.33Å; L216-T220 HydrophobicContact CD1-CG2 3.7Å; L216-T220 HydrophobicContact CG-CG2 4.34Å; L216-T220 WeakPolarHBondContact O-CB 3.33Å; L216-T220 VanDerWaalsContact O-CG2 3.29Å; L216-T220 WeakPolarHBondContact O-CG2 3.39Å; L216-T220 PolarHBondContact O-N 3.12Å; L216-T220 PolarHBondContact O-OG1 3.33Å; T220-D222 PolarHBondContact O-N 3.45Å; T220-D222 WeakPolarHBondContact OG1-CB 3.34Å
221G94.6Very high97.3Very high58 Ų5829 Ų2960%0.59816%0.155SC*.THydrogen-bonded Turntrans69.413.8-173.700000114.8S217S217-G221 CarbonylContact O-C 3.5Å; S217-G221 WeakPolarHBondContact O-CA 3.49Å; S217-G221 PolarHBondContact O-N 3.06Å
222D95.8Very high97.2Very high48 Ų4829 Ų2926%0.25716%0.155SC..  trans-112.4102.9-171.5-164.3-20.1000110.8K161 S217 T220 V224 F225K161-D222 WeakPolarHBondContact CE-OD2 3.39Å; K161-D222 VanDerWaalsContact NZ-CB 3.31Å; K161-D222 IonicContact NZ-OD2 3.26Å; K161-D222 PolarHBondContact NZ-OD2 3.39Å; S217-D222 VanDerWaalsContact CA-O 3.27Å; S217-D222 WeakPolarHBondContact CA-O 3.45Å; S217-D222 WeakPolarHBondContact CB-O 3.41Å; S217-D222 PolarHBondContact O-N 2.8Å; S217-D222 PolarHBondContact OG-O 3.29Å; T220-D222 PolarHBondContact O-N 3.45Å; T220-D222 WeakPolarHBondContact OG1-CB 3.34Å; D222-V224 PolarHBondContact O-N 3.29Å; D222-V224 VanDerWaalsContact O-N 3.11Å; D222-V224 VanDerWaalsContact OD1-CG1 3.29Å; D222-V224 WeakPolarHBondContact OD1-CG1 3.31Å; D222-F225 HydrophobicContact CB-CE2 4.17Å
223P96.1Very high97.2Very high41 Ų4129.1 Ų29.127%0.26616%0.155SC..THydrogen-bonded Turntrans-70.3-9.1-170.629.9-36.3000113.9F225 E226 D227 A483P223-F225 PolarHBondContact O-N 3.42Å; P223-F225 VanDerWaalsContact O-N 3.1Å; P223-E226 PolarHBondContact O-N 3Å; P223-D227 WeakPolarHBondContact O-CB 3.26Å; P223-D227 PolarHBondContact O-N 3.1Å; P223-A483 HydrophobicContact CG-CB 4.31Å
224V97.6Very high97.2Very high42 Ų4231.4 Ų31.426%0.25517%0.168SC..Hα-helixtrans-56.4-32.9-172.771.40000113.3L168 D222 H228L168-V224 HydrophobicContact CD1-CG1 4.02Å; L168-V224 HydrophobicContact CD1-CG2 3.97Å; D222-V224 PolarHBondContact O-N 3.29Å; D222-V224 VanDerWaalsContact O-N 3.11Å; D222-V224 VanDerWaalsContact OD1-CG1 3.29Å; D222-V224 WeakPolarHBondContact OD1-CG1 3.31Å; V224-H228 PolarHBondContact O-N 3.33Å; V224-H228 PolarHBondContact O-ND1 3.02Å
225F98.4Very high97.2Very high0 Ų033.1 Ų33.10%018%0.175CC..Hα-helixtrans-73.6-56.2-179.7-47.8-73.1000110.5K161 L165 L168 F213 L216 D222 P223 D227 H228 A229K161-F225 HydrophobicContact CG-CE2 4.45Å; K161-F225 HydrophobicContact CG-CZ 4.14Å; L165-F225 HydrophobicContact CD2-CE1 4.1Å; L165-F225 HydrophobicContact CD2-CZ 3.97Å; L165-F225 HydrophobicContact CG-CE1 4.26Å; L165-F225 HydrophobicContact CG-CZ 4.09Å; L168-F225 HydrophobicContact CD1-CD1 4.07Å; L168-F225 HydrophobicContact CD1-CE1 3.78Å; L168-F225 HydrophobicContact CD2-CD1 4.01Å; L168-F225 HydrophobicContact CG-CD1 4Å; L168-F225 HydrophobicContact CG-CE1 4.04Å; F213-F225 HydrophobicContact CB-CB 3.8Å; F213-F225 HydrophobicContact CD2-CB 3.83Å; F213-F225 WeakPolarHBondContact CD2-O 3.35Å; F213-F225 HydrophobicContact CG-CB 3.94Å; F213-F225 WeakPolarHBondContact O-CB 3.36Å; L216-F225 HydrophobicContact CB-CD2 4.38Å; L216-F225 HydrophobicContact CD2-CB 4.43Å; L216-F225 HydrophobicContact CD2-CD1 3.81Å; L216-F225 HydrophobicContact CD2-CD2 3.63Å; L216-F225 HydrophobicContact CD2-CE1 3.91Å; L216-F225 HydrophobicContact CD2-CE2 3.73Å; L216-F225 HydrophobicContact CD2-CG 3.68Å; L216-F225 HydrophobicContact CD2-CZ 3.87Å; L216-F225 HydrophobicContact CG-CD2 3.75Å; L216-F225 HydrophobicContact CG-CE2 3.89Å; L216-F225 HydrophobicContact CG-CG 4.22Å; L216-F225 HydrophobicContact CG-CZ 4.49Å; D222-F225 HydrophobicContact CB-CE2 4.17Å; P223-F225 PolarHBondContact O-N 3.42Å; P223-F225 VanDerWaalsContact O-N 3.1Å; F225-D227 PolarHBondContact O-N 3.35Å; F225-H228 PolarHBondContact O-N 3.13Å; F225-A229 PolarHBondContact O-N 2.83Å; F225-A229 VanDerWaalsContact O-N 3.14Å
226E97.1Very high97.2Very high8 Ų833.1 Ų33.14%0.03718%0.175CC..Hα-helixtrans-53.6-43176.3-164.6179.5139.800111.8I210 A214 S217 R218 P223 H228 A229 R230I210-E226 HydrophobicContact CD1-CG 3.94Å; A214-E226 HydrophobicContact CB-CB 4.38Å; A214-E226 HydrophobicContact CB-CG 3.87Å; S217-E226 PolarHBondContact OG-N 3.35Å; R218-E226 IonicContact CZ-OE2 3.33Å; R218-E226 IonicContact NE-OE2 2.7Å; R218-E226 PolarHBondContact NE-OE2 3.38Å; R218-E226 IonicContact NH2-OE1 2.82Å; R218-E226 PolarHBondContact NH2-OE1 3.04Å; R218-E226 IonicContact NH2-OE2 3.34Å; R218-E226 PolarHBondContact NH2-OE2 3.23Å; P223-E226 PolarHBondContact O-N 3Å; E226-H228 VanDerWaalsContact C-N 3.26Å; E226-H228 PolarHBondContact O-N 3.25Å; E226-A229 PolarHBondContact O-N 3.14Å; E226-R230 WeakPolarHBondContact O-CB 3.49Å; E226-R230 PolarHBondContact O-N 2.54Å; E226-R230 IonicContact OE1-CZ 3.57Å; E226-R230 IonicContact OE1-NE 3.81Å; E226-R230 PolarHBondContact OE1-NE 3.33Å; E226-R230 IonicContact OE1-NH2 3.47Å; E226-R230 PolarHBondContact OE1-NH2 2.9Å
227D97.6Very high97.2Very high63 Ų6334.5 Ų34.534%0.33718%0.18SC..Hα-helixtrans-62.5-26.4179.1-76.1-20.2000113.5P223 F225 R231P223-D227 WeakPolarHBondContact O-CB 3.26Å; P223-D227 PolarHBondContact O-N 3.1Å; F225-D227 PolarHBondContact O-N 3.35Å; D227-R231 WeakPolarHBondContact O-CG 3.4Å; D227-R231 PolarHBondContact O-NE 2.88Å; D227-R231 PolarHBondContact O-NH2 3.43Å
228H98.3Very high97.1Very high44 Ų4441.2 Ų41.220%0.20421%0.211CC..Hα-helixtrans-82-48.1173.6-7784.4000111.8L168 F171 V224 F225 E226 R230 R231 A232L168-H228 HydrophobicContact CD2-CB 4.14Å; F171-H228 HydrophobicContact CB-CB 4.42Å; F171-H228 HydrophobicContact CD1-CB 3.95Å; F171-H228 HydrophobicContact CD2-CB 4.47Å; F171-H228 HydrophobicContact CE1-CB 4.29Å; F171-H228 HydrophobicContact CG-CB 4.04Å; V224-H228 PolarHBondContact O-N 3.33Å; V224-H228 PolarHBondContact O-ND1 3.02Å; F225-H228 PolarHBondContact O-N 3.13Å; E226-H228 VanDerWaalsContact C-N 3.26Å; E226-H228 PolarHBondContact O-N 3.25Å; H228-R230 VanDerWaalsContact C-N 3.35Å; H228-R230 PolarHBondContact O-N 3.38Å; H228-R231 PolarHBondContact CD2-NH2 3.44Å; H228-R231 PolarHBondContact CE1-NH2 3.13Å; H228-R231 PolarHBondContact ND1-NH2 3Å; H228-R231 PolarHBondContact NE2-NH2 3.11Å; H228-R231 PolarHBondContact O-N 3.47Å; H228-A232 PolarHBondContact O-N 3.34Å; H228-A232 VanDerWaalsContact O-N 3.16Å
229A98.1Very high97.2Very high2 Ų242.5 Ų42.52%0.01722%0.218CC..Hα-helixtrans-64-38.6179.700000112.6M209 I210 F213 F225 E226 A232 L233M209-A229 HydrophobicContact CB-CB 3.95Å; I210-A229 HydrophobicContact CB-CB 4.25Å; I210-A229 HydrophobicContact CD1-CB 3.89Å; F213-A229 HydrophobicContact CB-CB 3.88Å; F213-A229 HydrophobicContact CD2-CB 4.13Å; F213-A229 HydrophobicContact CG-CB 4.25Å; F225-A229 PolarHBondContact O-N 2.83Å; F225-A229 VanDerWaalsContact O-N 3.14Å; E226-A229 PolarHBondContact O-N 3.14Å; A229-A232 PolarHBondContact O-N 2.7Å; A229-L233 PolarHBondContact O-N 2.7Å; A229-L233 VanDerWaalsContact O-N 3.12Å
230R97.1Very high97.3Very high50 Ų5043 Ų4319%0.18922%0.218CC..Hα-helixtrans-62.6-44.6176.6-175.8177-74.7-88.47.8111.8I210 E226 H228 A232 L233 D234 D285I210-R230 HydrophobicContact CD1-CB 4.3Å; E226-R230 WeakPolarHBondContact O-CB 3.49Å; E226-R230 PolarHBondContact O-N 2.54Å; E226-R230 IonicContact OE1-CZ 3.57Å; E226-R230 IonicContact OE1-NE 3.81Å; E226-R230 PolarHBondContact OE1-NE 3.33Å; E226-R230 IonicContact OE1-NH2 3.47Å; E226-R230 PolarHBondContact OE1-NH2 2.9Å; H228-R230 VanDerWaalsContact C-N 3.35Å; H228-R230 PolarHBondContact O-N 3.38Å; R230-A232 VanDerWaalsContact C-N 3.34Å; R230-A232 PolarHBondContact O-N 3.04Å; R230-L233 PolarHBondContact O-N 3.03Å; R230-D234 PolarHBondContact O-N 3.26Å; R230-D285 IonicContact CZ-OD2 2.75Å; R230-D285 IonicContact NH1-OD2 3.34Å; R230-D285 PolarHBondContact NH1-OD2 3.35Å; R230-D285 IonicContact NH2-OD2 2.73Å; R230-D285 PolarHBondContact NH2-OD2 3.04Å
231R97.9Very high97.2Very high122 Ų12243.5 Ų43.546%0.4622%0.218SC..Hα-helixtrans-62.9-36.9175.6-81.7-178.6-71.3148.84.4112.9D227 H228 D234 F235D227-R231 WeakPolarHBondContact O-CG 3.4Å; D227-R231 PolarHBondContact O-NE 2.88Å; D227-R231 PolarHBondContact O-NH2 3.43Å; H228-R231 PolarHBondContact CD2-NH2 3.44Å; H228-R231 PolarHBondContact CE1-NH2 3.13Å; H228-R231 PolarHBondContact ND1-NH2 3Å; H228-R231 PolarHBondContact NE2-NH2 3.11Å; H228-R231 PolarHBondContact O-N 3.47Å; R231-D234 PolarHBondContact O-N 3.42Å; R231-F235 PolarHBondContact O-N 2.86Å
232A98.2Very high97.1Very high0 Ų051.3 Ų51.30%023%0.229CC..Hα-helixtrans-63.1-44.8174.200000111.6F171 L177 H228 A229 R230 F235 L236F171-A232 HydrophobicContact CE1-CB 4.26Å; L177-A232 HydrophobicContact CD2-CB 4.1Å; L177-A232 WeakPolarHBondContact CD2-O 3.42Å; H228-A232 PolarHBondContact O-N 3.34Å; H228-A232 VanDerWaalsContact O-N 3.16Å; A229-A232 PolarHBondContact O-N 2.7Å; R230-A232 VanDerWaalsContact C-N 3.34Å; R230-A232 PolarHBondContact O-N 3.04Å; A232-F235 PolarHBondContact O-N 2.91Å; A232-L236 WeakPolarHBondContact O-CG 3.49Å; A232-L236 PolarHBondContact O-N 2.53Å
233L97.7Very high96.9Very high1 Ų155.6 Ų55.61%0.00525%0.252CS..Hα-helixtrans-64.9-37.4174.5-75.3175.8000113.5I210 A229 R230 W237 Y272 L276 F288I210-L233 HydrophobicContact CB-CD1 3.63Å; I210-L233 HydrophobicContact CG1-CD1 4.01Å; I210-L233 HydrophobicContact CG2-CD1 3.57Å; A229-L233 PolarHBondContact O-N 2.7Å; A229-L233 VanDerWaalsContact O-N 3.12Å; R230-L233 PolarHBondContact O-N 3.03Å; L233-W237 VanDerWaalsContact O-CB 3.27Å; L233-W237 WeakPolarHBondContact O-CB 3.38Å; L233-W237 PolarHBondContact O-N 3.11Å; L233-Y272 HydrophobicContact CD2-CD2 3.59Å; L233-Y272 HydrophobicContact CD2-CE2 3.55Å; L233-L276 HydrophobicContact CD2-CD2 4.36Å; L233-F288 HydrophobicContact CD1-CD1 4.46Å; L233-F288 HydrophobicContact CD1-CE1 3.79Å
234D97.7Very high96.8Very high49 Ų4953.8 Ų53.826%0.26224%0.24SC..Hα-helixtrans-61.3-44.5173.7-68.1-29.3000111.3R230 R231 W237 E238 R291R230-D234 PolarHBondContact O-N 3.26Å; R231-D234 PolarHBondContact O-N 3.42Å; D234-W237 WeakPolarHBondContact O-CB 3.47Å; D234-W237 PolarHBondContact O-N 2.8Å; D234-E238 PolarHBondContact O-N 3.4Å; D234-R291 IonicContact OD1-CZ 3.63Å; D234-R291 IonicContact OD1-NH1 2.8Å; D234-R291 PolarHBondContact OD1-NH1 3.27Å; D234-R291 IonicContact OD1-NH2 2.65Å; D234-R291 PolarHBondContact OD1-NH2 3.17Å
235F98.1Very high96.8Very high36 Ų3653.7 Ų53.716%0.15824%0.239CC..Hα-helixtrans-66.7-45.9177.5-169.4-88.2000112.2S175 L177 R231 A232 W237 E238 K239 I251S175-F235 VanDerWaalsContact CB-CE1 3.44Å; L177-F235 HydrophobicContact CD1-CD1 3.72Å; L177-F235 HydrophobicContact CD1-CE1 3.82Å; L177-F235 HydrophobicContact CD2-CB 4.26Å; L177-F235 HydrophobicContact CD2-CD1 3.93Å; L177-F235 HydrophobicContact CD2-CG 4.49Å; L177-F235 HydrophobicContact CG-CD1 3.75Å; L177-F235 HydrophobicContact CG-CE1 4.19Å; L177-F235 HydrophobicContact CG-CG 4.48Å; R231-F235 PolarHBondContact O-N 2.86Å; A232-F235 PolarHBondContact O-N 2.91Å; F235-W237 VanDerWaalsContact C-N 3.27Å; F235-W237 PolarHBondContact O-N 2.93Å; F235-E238 PolarHBondContact O-N 3.09Å; F235-K239 HydrophobicContact CD1-CG 3.95Å; F235-K239 HydrophobicContact CE1-CD 4.32Å; F235-K239 HydrophobicContact CE1-CG 3.77Å; F235-K239 HydrophobicContact CZ-CD 4.42Å; F235-K239 HydrophobicContact CZ-CG 4.33Å; F235-K239 VanDerWaalsContact O-CG 3.3Å; F235-K239 WeakPolarHBondContact O-CG 3.29Å; F235-K239 PolarHBondContact O-N 3.3Å; F235-K239 VanDerWaalsContact O-N 3.07Å; F235-I251 HydrophobicContact CE1-CD1 4.36Å
236L98Very high96.7Very high0 Ų053.7 Ų53.70%024%0.239CC..Hα-helixtrans-57.1-42.2174.3-72.3175.7000111.6L177 A206 A232 K239 R240 I251 W258 Y272L177-L236 HydrophobicContact CD1-CD2 4.36Å; L177-L236 HydrophobicContact CD2-CD1 4.5Å; L177-L236 HydrophobicContact CD2-CD2 3.96Å; L177-L236 HydrophobicContact CD2-CG 3.77Å; A206-L236 HydrophobicContact CB-CD1 4.15Å; A232-L236 WeakPolarHBondContact O-CG 3.49Å; A232-L236 PolarHBondContact O-N 2.53Å; L236-K239 PolarHBondContact O-N 3.19Å; L236-R240 PolarHBondContact O-N 3.4Å; L236-I251 HydrophobicContact CD2-CD1 4.32Å; L236-I251 HydrophobicContact CD2-CG2 4.2Å; L236-W258 HydrophobicContact CD2-CH2 4.37Å; L236-Y272 HydrophobicContact CB-CE2 3.9Å; L236-Y272 HydrophobicContact CD1-CD2 3.83Å; L236-Y272 HydrophobicContact CD1-CE2 3.84Å
237W97.6Very high96.8Very high28 Ų2853.3 Ų53.311%0.10624%0.237CC..Hα-helixtrans-60.4-46.9175.4172.6-114.7000112.2L233 D234 F235 K239 R240 R291 I294 H295L233-W237 VanDerWaalsContact O-CB 3.27Å; L233-W237 WeakPolarHBondContact O-CB 3.38Å; L233-W237 PolarHBondContact O-N 3.11Å; D234-W237 WeakPolarHBondContact O-CB 3.47Å; D234-W237 PolarHBondContact O-N 2.8Å; F235-W237 VanDerWaalsContact C-N 3.27Å; F235-W237 PolarHBondContact O-N 2.93Å; W237-K239 VanDerWaalsContact C-N 3.28Å; W237-K239 PolarHBondContact O-N 2.75Å; W237-R240 VanDerWaalsContact CE2-CZ 3.42Å; W237-R240 VanDerWaalsContact O-CD 3.31Å; W237-R240 WeakPolarHBondContact O-CD 3.06Å; W237-R240 WeakPolarHBondContact O-CG 3.39Å; W237-R240 PolarHBondContact O-N 2.96Å; W237-R240 PolarHBondContact O-NH1 3.31Å; W237-R291 HydrophobicContact CD2-CB 4.36Å; W237-R291 HydrophobicContact CD2-CG 3.59Å; W237-R291 HydrophobicContact CE3-CB 3.9Å; W237-R291 HydrophobicContact CE3-CG 3.65Å; W237-R291 HydrophobicContact CG-CG 4.15Å; W237-R291 HydrophobicContact CH2-CB 4.27Å; W237-R291 HydrophobicContact CH2-CG 4Å; W237-R291 HydrophobicContact CZ2-CG 3.94Å; W237-R291 HydrophobicContact CZ3-CB 3.86Å; W237-R291 HydrophobicContact CZ3-CG 3.87Å; W237-I294 HydrophobicContact CH2-CB 3.91Å; W237-I294 HydrophobicContact CH2-CD1 3.74Å; W237-I294 HydrophobicContact CH2-CG1 4.42Å; W237-I294 HydrophobicContact CH2-CG2 3.8Å; W237-I294 HydrophobicContact CZ2-CD1 4.22Å; W237-I294 HydrophobicContact CZ3-CB 4.37Å; W237-I294 HydrophobicContact CZ3-CG2 4.22Å; W237-H295 AromaticContact CE3-NE2 3.46Å; W237-H295 AromaticContact CZ3-CD2 3.96Å; W237-H295 AromaticContact CZ3-NE2 3.58Å
238E97Very high96.7Very high148 Ų14850.3 Ų50.369%0.69222%0.221SC*.Hα-helixtrans-61.7-33.4177.3-75.6-168.8172.400113.4D234 F235 R240D234-E238 PolarHBondContact O-N 3.4Å; F235-E238 PolarHBondContact O-N 3.09Å; E238-R240 VanDerWaalsContact C-N 3.35Å; E238-R240 PolarHBondContact O-N 3.48Å
239K97Very high96.6Very high63 Ų6348.8 Ų48.827%0.27421%0.214SC..Hα-helixtrans-80-8.5-177.4-64.3-60.5-168144.30114.6F235 L236 W237 I251 S255 G256 W258F235-K239 HydrophobicContact CD1-CG 3.95Å; F235-K239 HydrophobicContact CE1-CD 4.32Å; F235-K239 HydrophobicContact CE1-CG 3.77Å; F235-K239 HydrophobicContact CZ-CD 4.42Å; F235-K239 HydrophobicContact CZ-CG 4.33Å; F235-K239 VanDerWaalsContact O-CG 3.3Å; F235-K239 WeakPolarHBondContact O-CG 3.29Å; F235-K239 PolarHBondContact O-N 3.3Å; F235-K239 VanDerWaalsContact O-N 3.07Å; L236-K239 PolarHBondContact O-N 3.19Å; W237-K239 VanDerWaalsContact C-N 3.28Å; W237-K239 PolarHBondContact O-N 2.75Å; K239-I251 HydrophobicContact CB-CD1 4.06Å; K239-I251 HydrophobicContact CG-CD1 4.05Å; K239-S255 PolarHBondContact NZ-O 2.6Å; K239-G256 VanDerWaalsContact CD-O 3.23Å; K239-G256 WeakPolarHBondContact CD-O 3.2Å; K239-G256 VanDerWaalsContact CE-O 3.26Å; K239-G256 WeakPolarHBondContact CE-O 3.46Å; K239-G256 PolarHBondContact NZ-O 2.92Å; K239-W258 HydrophobicContact CB-CZ2 3.92Å; K239-W258 PolarHBondContact O-NE1 2.87Å
240R96.3Very high96.5Very high63 Ų6349.7 Ų49.724%0.23822%0.22CC..SBendtrans-54.5144.2176.579.5-168.5-177.1-84.48112.3L236 W237 E238 R242 N245 V247L236-R240 PolarHBondContact O-N 3.4Å; W237-R240 VanDerWaalsContact CE2-CZ 3.42Å; W237-R240 VanDerWaalsContact O-CD 3.31Å; W237-R240 WeakPolarHBondContact O-CD 3.06Å; W237-R240 WeakPolarHBondContact O-CG 3.39Å; W237-R240 PolarHBondContact O-N 2.96Å; W237-R240 PolarHBondContact O-NH1 3.31Å; E238-R240 VanDerWaalsContact C-N 3.35Å; E238-R240 PolarHBondContact O-N 3.48Å; R240-R242 PolarHBondContact O-N 3.01Å; R240-N245 PolarHBondContact NE-OD1 2.95Å; R240-N245 VanDerWaalsContact NE-OD1 3.1Å; R240-V247 HydrophobicContact CB-CG1 3.89Å
241Q95.9Very high96.5Very high48 Ų4847.3 Ų47.322%0.22421%0.211CC..BIsolated β-bridgetrans-72.2114.2-176174.556-10.300111.6N243 S244 N245 L246 I314 H315Q241-N243 VanDerWaalsContact C-N 3.25Å; Q241-N243 PolarHBondContact O-N 3.04Å; Q241-S244 WeakPolarHBondContact CG-OG 3.03Å; Q241-S244 PolarHBondContact O-N 3.03Å; Q241-S244 PolarHBondContact O-OG 2.79Å; Q241-N245 WeakPolarHBondContact O-CA 3.37Å; Q241-N245 PolarHBondContact O-N 3.12Å; Q241-L246 PolarHBondContact N-O 3.17Å; Q241-I314 HydrophobicContact CB-CB 4.08Å; Q241-I314 HydrophobicContact CB-CG1 4.31Å; Q241-I314 HydrophobicContact CG-CB 4.46Å; Q241-I314 WeakPolarHBondContact CG-O 3.28Å; Q241-H315 PolarHBondContact NE2-CD2 2.67Å
242R91.8Very high96.5Very high222 Ų22242.9 Ų42.984%0.83820%0.196SC*.THydrogen-bonded Turntrans-53.3-30.8-165.4-65.3-176.7178.9-177.4-0.9116.3R240R240-R242 PolarHBondContact O-N 3.01Å
243N91.4Very high96.5Very high138 Ų13842.9 Ų42.974%0.73820%0.196SC*.THydrogen-bonded Turntrans-86.8-16.3-177.7-65.6-4000113.8Q241Q241-N243 VanDerWaalsContact C-N 3.25Å; Q241-N243 PolarHBondContact O-N 3.04Å
244S94.6Very high96.4Very high2 Ų246.3 Ų46.31%0.01421%0.212CC..THydrogen-bonded Turntrans-126.9-14.7-172.857.20000113.7Q241 L246 S298 I314Q241-S244 WeakPolarHBondContact CG-OG 3.03Å; Q241-S244 PolarHBondContact O-N 3.03Å; Q241-S244 PolarHBondContact O-OG 2.79Å; S244-L246 PolarHBondContact O-N 2.87Å; S244-L246 VanDerWaalsContact O-N 3.09Å; S244-S298 WeakPolarHBondContact O-CB 3.48Å; S244-S298 PolarHBondContact O-OG 2.88Å; S244-I314 PolarHBondContact OG-O 3.43Å
245N97.1Very high96.3Very high41 Ų4146.8 Ų46.822%0.21922%0.219CC..THydrogen-bonded Turntrans48.921.9-166.9-56.2-70.4000114.2R240 Q241 I294 H295R240-N245 PolarHBondContact NE-OD1 2.95Å; R240-N245 VanDerWaalsContact NE-OD1 3.1Å; Q241-N245 WeakPolarHBondContact O-CA 3.37Å; Q241-N245 PolarHBondContact O-N 3.12Å; N245-I294 HydrophobicContact CB-CG2 3.79Å; N245-H295 PolarHBondContact O-CE1 2.85Å; N245-H295 VanDerWaalsContact O-CE1 3.25Å; N245-H295 PolarHBondContact O-ND1 3.44Å
246L97.2Very high96.2Very high0 Ų045.1 Ų45.10%021%0.213CC..BIsolated β-bridgetrans-87.2150.9174.5-62.9-178.6000110.7Q241 S244 Y302 I303 V312 I314 P317Q241-L246 PolarHBondContact N-O 3.17Å; S244-L246 PolarHBondContact O-N 2.87Å; S244-L246 VanDerWaalsContact O-N 3.09Å; L246-Y302 HydrophobicContact CD1-CD2 4.23Å; L246-Y302 HydrophobicContact CG-CD2 4.45Å; L246-I303 HydrophobicContact CD2-CD1 3.91Å; L246-V312 HydrophobicContact CD1-CG2 3.62Å; L246-I314 HydrophobicContact CB-CB 4.19Å; L246-I314 HydrophobicContact CB-CG2 3.81Å; L246-P317 HydrophobicContact CD1-CB 3.96Å
247V97.6Very high96.1Very high0 Ų051 Ų510%024%0.24CC..  trans-112.9148.7175.3-72.50000108.8T203 R240 W258 S263 I269 Y272 Y273 I314T203-V247 HydrophobicContact CG2-CB 4.4Å; T203-V247 HydrophobicContact CG2-CG2 4.01Å; R240-V247 HydrophobicContact CB-CG1 3.89Å; V247-W258 HydrophobicContact CB-CH2 3.61Å; V247-W258 HydrophobicContact CB-CZ2 3.82Å; V247-W258 HydrophobicContact CB-CZ3 4.4Å; V247-W258 HydrophobicContact CG1-CH2 3.96Å; V247-W258 HydrophobicContact CG1-CZ2 3.84Å; V247-S263 WeakPolarHBondContact O-CB 3.48Å; V247-S263 PolarHBondContact O-OG 3.41Å; V247-I269 HydrophobicContact CG2-CG2 3.91Å; V247-Y272 HydrophobicContact CG1-CE1 4.43Å; V247-Y272 HydrophobicContact CG2-CD1 4.26Å; V247-Y272 HydrophobicContact CG2-CE1 3.99Å; V247-Y273 HydrophobicContact CG2-CE1 4.13Å; V247-Y273 WeakPolarHBondContact CG2-OH 3.47Å; V247-I314 WeakPolarHBondContact O-CG2 3.42Å
248G96.6Very high96Very high0 Ų050.5 Ų50.50%024%0.238CC..  trans-78.1173.2178.300000112.3T203 W258 R260 D262T203-G248 PolarHBondContact OG1-O 3.38Å; G248-W258 VanDerWaalsContact N-CE3 3.26Å; G248-W258 VanDerWaalsContact N-CZ3 3.26Å; G248-W258 WeakPolarHBondContact O-CZ3 3.35Å; G248-R260 WeakPolarHBondContact CA-O 3.2Å; G248-D262 CarbonylContact C-O 3.55Å; G248-D262 VanDerWaalsContact CA-O 3.32Å; G248-D262 WeakPolarHBondContact CA-O 3.29Å
249T95.4Very high96Very high11 Ų1146.9 Ų46.97%0.06723%0.226CC..SBendtrans-76.5-30.2174.1-490000113.3C202 T203 R260 D262 I269C202-T249 VanDerWaalsContact CA-O 3.29Å; C202-T249 WeakPolarHBondContact CA-O 3.09Å; T203-T249 PolarHBondContact N-O 2.97Å; T203-T249 VanDerWaalsContact N-O 3.12Å; T249-R260 PolarHBondContact N-O 3.02Å; T249-D262 PolarHBondContact N-O 3.36Å; T249-D262 VanDerWaalsContact N-O 3.15Å; T249-D262 PolarHBondContact OG1-O 3.07Å; T249-I269 HydrophobicContact CG2-CG1 4.41Å
250T96.8Very high95.8Very high22 Ų2251 Ų5114%0.13524%0.24CC..EExtended strand (participates in β ladder)trans-139.6131.4-174.9-47.20000111.2D200 T201 V259 R260D200-T250 HydrophobicContact CB-CG2 4.08Å; T201-T250 WeakPolarHBondContact O-CA 3.23Å; T201-T250 WeakPolarHBondContact O-CG2 3.49Å; T250-V259 HydrophobicContact CG2-CB 4.42Å; T250-V259 PolarHBondContact O-N 2.81Å; T250-R260 PolarHBondContact O-N 3.13Å; T250-R260 WeakPolarHBondContact OG1-CD 3.48Å; T250-R260 WeakPolarHBondContact OG1-CG 3.14Å
251I97.5Very high95.7Very high0 Ų053.6 Ų53.60%025%0.249CC..EExtended strand (participates in β ladder)trans-126142.5-176.6-169.7166.1000111L177 D200 T201 F235 L236 K239 E257 W258L177-I251 HydrophobicContact CD1-CD1 4.1Å; L177-I251 HydrophobicContact CD1-CG1 4.34Å; L177-I251 HydrophobicContact CD1-CG2 3.74Å; D200-I251 WeakPolarHBondContact CA-O 3.26Å; T201-I251 HydrophobicContact CG2-CG2 3.93Å; T201-I251 PolarHBondContact N-O 3.16Å; T201-I251 PolarHBondContact O-N 2.87Å; F235-I251 HydrophobicContact CE1-CD1 4.36Å; L236-I251 HydrophobicContact CD2-CD1 4.32Å; L236-I251 HydrophobicContact CD2-CG2 4.2Å; K239-I251 HydrophobicContact CB-CD1 4.06Å; K239-I251 HydrophobicContact CG-CD1 4.05Å; I251-E257 WeakPolarHBondContact CA-O 3.41Å; I251-W258 HydrophobicContact CB-CE3 3.81Å; I251-W258 HydrophobicContact CB-CH2 4.37Å; I251-W258 HydrophobicContact CB-CZ3 3.67Å; I251-W258 HydrophobicContact CD1-CD2 4.48Å; I251-W258 HydrophobicContact CD1-CE3 4.33Å; I251-W258 HydrophobicContact CD1-CH2 3.95Å; I251-W258 HydrophobicContact CD1-CZ2 4.11Å; I251-W258 HydrophobicContact CD1-CZ3 4.07Å; I251-W258 HydrophobicContact CG1-CE3 4.25Å; I251-W258 HydrophobicContact CG1-CZ3 4.27Å; I251-W258 HydrophobicContact CG2-CZ3 4.37Å
252N97.8Very high95.7Very high28 Ų2852.6 Ų52.615%0.1525%0.246CC..EExtended strand (participates in β ladder)trans-77.4126.1173.5-175-84.9000110.9T199 D200 H254 S255 G256 E257 V259T199-N252 WeakPolarHBondContact CB-ND2 3.07Å; T199-N252 CarbonylContact O-C 3.53Å; T199-N252 VanDerWaalsContact O-CA 3.28Å; T199-N252 WeakPolarHBondContact O-CA 3.44Å; T199-N252 VanDerWaalsContact O-CG 3.31Å; T199-N252 PolarHBondContact O-ND2 3.4Å; T199-N252 VanDerWaalsContact O-ND2 3.12Å; T199-N252 PolarHBondContact OG1-ND2 3.25Å; D200-N252 PolarHBondContact OD1-ND2 3.49Å; N252-H254 PolarHBondContact O-N 2.93Å; N252-H254 PolarHBondContact OD1-N 2.64Å; N252-H254 VanDerWaalsContact OD1-N 3.08Å; N252-S255 WeakPolarHBondContact CB-OG 3.48Å; N252-S255 PolarHBondContact OD1-N 3.21Å; N252-S255 PolarHBondContact OD1-OG 2.99Å; N252-G256 WeakPolarHBondContact O-CA 3.28Å; N252-G256 PolarHBondContact O-N 3.22Å; N252-E257 PolarHBondContact N-O 2.88Å; N252-V259 HydrophobicContact CB-CG2 4.13Å
253I96.9Very high95.9Very high0 Ų042 Ų420%021%0.206CC..THydrogen-bonded Turntrans-76.2-5.9-173.674-163.7000114.1T173 S175 L177 Y179 E198 T199 T201T173-I253 HydrophobicContact CG2-CB 4.12Å; T173-I253 HydrophobicContact CG2-CD1 3.75Å; T173-I253 HydrophobicContact CG2-CG1 3.81Å; S175-I253 VanDerWaalsContact CB-O 3.29Å; S175-I253 WeakPolarHBondContact CB-O 3.21Å; S175-I253 PolarHBondContact N-O 3.01Å; S175-I253 PolarHBondContact OG-O 3.23Å; L177-I253 HydrophobicContact CB-CB 4.34Å; L177-I253 HydrophobicContact CB-CG2 4.21Å; Y179-I253 HydrophobicContact CD1-CD1 3.33Å; Y179-I253 HydrophobicContact CE1-CD1 3.57Å; Y179-I253 HydrophobicContact CG-CD1 3.91Å; E198-I253 WeakPolarHBondContact O-CD1 3.19Å; T199-I253 WeakPolarHBondContact O-CG1 3.34Å; T199-I253 PolarHBondContact O-N 2.89Å; T201-I253 HydrophobicContact CG2-CG2 3.44Å; T201-I253 VanDerWaalsContact CG2-CG2 3.44Å
254H95.4Very high96Very high74 Ų7435.5 Ų35.534%0.34317%0.171SC..THydrogen-bonded Turntrans-106.7-48.2176.9-67.5-78.9000113S174 N252S174-H254 PolarHBondContact OG-ND1 3.2Å; N252-H254 PolarHBondContact O-N 2.93Å; N252-H254 PolarHBondContact OD1-N 2.64Å; N252-H254 VanDerWaalsContact OD1-N 3.08Å
255S96Very high96.1Very high58 Ų5835.4 Ų35.441%0.40617%0.171SC..THydrogen-bonded Turntrans-85.3-26.5176.667.50000113K239 N252 E257K239-S255 PolarHBondContact NZ-O 2.6Å; N252-S255 WeakPolarHBondContact CB-OG 3.48Å; N252-S255 PolarHBondContact OD1-N 3.21Å; N252-S255 PolarHBondContact OD1-OG 2.99Å; S255-E257 VanDerWaalsContact C-N 3.27Å; S255-E257 PolarHBondContact OG-N 3.04Å; S255-E257 VanDerWaalsContact OG-N 3.14Å
256G95.4Very high95.9Very high2 Ų233.7 Ų33.72%0.02116%0.162CC..  trans62.234.4-166.300000112.6K239 N252K239-G256 VanDerWaalsContact CD-O 3.23Å; K239-G256 WeakPolarHBondContact CD-O 3.2Å; K239-G256 VanDerWaalsContact CE-O 3.26Å; K239-G256 WeakPolarHBondContact CE-O 3.46Å; K239-G256 PolarHBondContact NZ-O 2.92Å; N252-G256 WeakPolarHBondContact O-CA 3.28Å; N252-G256 PolarHBondContact O-N 3.22Å
257E96.2Very high95.6Very high122 Ų12235.4 Ų35.457%0.5718%0.177SC*.  trans-89.9143.7168.6-69.1-160.2163.200111.4I251 N252 S255 V259I251-E257 WeakPolarHBondContact CA-O 3.41Å; N252-E257 PolarHBondContact N-O 2.88Å; S255-E257 VanDerWaalsContact C-N 3.27Å; S255-E257 PolarHBondContact OG-N 3.04Å; S255-E257 VanDerWaalsContact OG-N 3.14Å; E257-V259 PolarHBondContact O-N 3.37Å
258W96.8Very high95.3Very high19 Ų1936.1 Ų36.17%0.07218%0.184CC..EExtended strand (participates in β ladder)trans-72.8114.7174.1-62.9109.2000110.4T203 L236 K239 V247 G248 I251 R261 I314T203-W258 WeakPolarHBondContact OG1-CZ3 3.43Å; L236-W258 HydrophobicContact CD2-CH2 4.37Å; K239-W258 HydrophobicContact CB-CZ2 3.92Å; K239-W258 PolarHBondContact O-NE1 2.87Å; V247-W258 HydrophobicContact CB-CH2 3.61Å; V247-W258 HydrophobicContact CB-CZ2 3.82Å; V247-W258 HydrophobicContact CB-CZ3 4.4Å; V247-W258 HydrophobicContact CG1-CH2 3.96Å; V247-W258 HydrophobicContact CG1-CZ2 3.84Å; G248-W258 VanDerWaalsContact N-CE3 3.26Å; G248-W258 VanDerWaalsContact N-CZ3 3.26Å; G248-W258 WeakPolarHBondContact O-CZ3 3.35Å; I251-W258 HydrophobicContact CB-CE3 3.81Å; I251-W258 HydrophobicContact CB-CH2 4.37Å; I251-W258 HydrophobicContact CB-CZ3 3.67Å; I251-W258 HydrophobicContact CD1-CD2 4.48Å; I251-W258 HydrophobicContact CD1-CE3 4.33Å; I251-W258 HydrophobicContact CD1-CH2 3.95Å; I251-W258 HydrophobicContact CD1-CZ2 4.11Å; I251-W258 HydrophobicContact CD1-CZ3 4.07Å; I251-W258 HydrophobicContact CG1-CE3 4.25Å; I251-W258 HydrophobicContact CG1-CZ3 4.27Å; I251-W258 HydrophobicContact CG2-CZ3 4.37Å; W258-R261 HydrophobicContact CB-CG 3.89Å; W258-R261 PolarHBondContact O-NE 2.84Å; W258-R261 PolarHBondContact O-NH2 3.12Å; W258-R261 VanDerWaalsContact O-NH2 3.16Å; W258-I314 HydrophobicContact CB-CD1 4.03Å; W258-I314 HydrophobicContact CD2-CD1 4.34Å; W258-I314 HydrophobicContact CG-CD1 3.71Å
259V95.4Very high95.3Very high72 Ų7236.1 Ų36.144%0.43618%0.184SC..EExtended strand (participates in β ladder)trans-83.1-57.1176.4179.80000108.9T250 N252 E257T250-V259 HydrophobicContact CG2-CB 4.42Å; T250-V259 PolarHBondContact O-N 2.81Å; N252-V259 HydrophobicContact CB-CG2 4.13Å; E257-V259 PolarHBondContact O-N 3.37Å
260R93.2Very high95.4Very high150 Ų15036.5 Ų36.557%0.56619%0.185SC*.EExtended strand (participates in β ladder)trans-93.6126.4167.7-63.3-165.9-175.5-164.73.7109.4G248 T249 T250 D262G248-R260 WeakPolarHBondContact CA-O 3.2Å; T249-R260 PolarHBondContact N-O 3.02Å; T250-R260 PolarHBondContact O-N 3.13Å; T250-R260 WeakPolarHBondContact OG1-CD 3.48Å; T250-R260 WeakPolarHBondContact OG1-CG 3.14Å; R260-D262 WeakPolarHBondContact CB-OD1 3.4Å
261R95.1Very high95.4Very high116 Ų11635.5 Ų35.544%0.43818%0.179SC..  trans-119.52.2-164-63176.1-177.5-177.20.6113.3W258 H313 I314W258-R261 HydrophobicContact CB-CG 3.89Å; W258-R261 PolarHBondContact O-NE 2.84Å; W258-R261 PolarHBondContact O-NH2 3.12Å; W258-R261 VanDerWaalsContact O-NH2 3.16Å; R261-H313 WeakPolarHBondContact O-CA 3.37Å; R261-I314 HydrophobicContact CB-CD1 4.34Å; R261-I314 HydrophobicContact CB-CG1 4.38Å; R261-I314 HydrophobicContact CG-CD1 4.44Å; R261-I314 PolarHBondContact O-N 3.39Å
262D94.8Very high95.4Very high27 Ų2735.5 Ų35.514%0.14418%0.179CC..EExtended strand (participates in β ladder)trans-62.5153.115446.2-41.2000111G248 T249 R260 V312 A321 R322G248-D262 CarbonylContact C-O 3.55Å; G248-D262 VanDerWaalsContact CA-O 3.32Å; G248-D262 WeakPolarHBondContact CA-O 3.29Å; T249-D262 PolarHBondContact N-O 3.36Å; T249-D262 VanDerWaalsContact N-O 3.15Å; T249-D262 PolarHBondContact OG1-O 3.07Å; R260-D262 WeakPolarHBondContact CB-OD1 3.4Å; D262-V312 CarbonylContact C-O 3.5Å; D262-A321 HydrophobicContact CB-CB 3.6Å; D262-R322 IonicContact OD2-CZ 2.62Å; D262-R322 IonicContact OD2-NE 3.16Å; D262-R322 PolarHBondContact OD2-NE 3.37Å; D262-R322 IonicContact OD2-NH2 2.68Å; D262-R322 PolarHBondContact OD2-NH2 2.85Å
263S96.3Very high95.5Very high0 Ų034.2 Ų34.20%017%0.172CC..EExtended strand (participates in β ladder)trans-157.7124.3-174.1-171.40000109.5V247 D311 V312 I314V247-S263 WeakPolarHBondContact O-CB 3.48Å; V247-S263 PolarHBondContact O-OG 3.41Å; S263-D311 CarbonylContact O-C 3.48Å; S263-D311 VanDerWaalsContact O-CA 3.27Å; S263-D311 WeakPolarHBondContact O-CA 3.42Å; S263-V312 PolarHBondContact N-O 3.04Å; S263-V312 PolarHBondContact O-N 3.06Å; S263-I314 VanDerWaalsContact CB-CG2 3.46Å
264G94.8Very high95.5Very high1 Ų134.4 Ų34.41%0.0117%0.173CC..  trans-145-158.1-178.600000109.8D311G264-D311 WeakPolarHBondContact CA-OD1 3.26Å
265V95.3Very high95.7Very high1 Ų130.9 Ų30.91%0.00616%0.157CC..SBendtrans-109.1-8.8167.8-67.20000112.9D270 I299 I303 L309 L329 F331 F332V265-D270 VanDerWaalsContact O-CA 3.27Å; V265-D270 WeakPolarHBondContact O-CA 3.4Å; V265-D270 WeakPolarHBondContact O-CB 3.48Å; V265-D270 PolarHBondContact O-N 2.87Å; V265-I299 HydrophobicContact CG1-CD1 4.18Å; V265-I299 HydrophobicContact CG1-CG1 4.34Å; V265-I299 HydrophobicContact CG1-CG2 3.54Å; V265-I303 HydrophobicContact CG1-CG2 4.46Å; V265-L309 HydrophobicContact CG2-CB 4.03Å; V265-L309 HydrophobicContact CG2-CD1 3.64Å; V265-L309 HydrophobicContact CG2-CG 4.46Å; V265-L329 HydrophobicContact CG2-CB 3.88Å; V265-F331 WeakPolarHBondContact O-CE1 3.4Å; V265-F332 HydrophobicContact CB-CD2 3.98Å; V265-F332 HydrophobicContact CB-CE2 4.35Å; V265-F332 HydrophobicContact CB-CG 4.2Å; V265-F332 HydrophobicContact CG1-CD1 4.41Å; V265-F332 HydrophobicContact CG1-CD2 3.78Å; V265-F332 HydrophobicContact CG1-CE1 4.28Å; V265-F332 HydrophobicContact CG1-CE2 3.64Å; V265-F332 HydrophobicContact CG1-CG 4.18Å; V265-F332 HydrophobicContact CG1-CZ 3.91Å; V265-F332 HydrophobicContact CG2-CB 4.47Å; V265-F332 HydrophobicContact CG2-CG 4.33Å
266G92.9Very high95.8Very high4 Ų428.1 Ų28.14%0.04114%0.138CC..SBendtrans-86.9-153.7-179.200000114G268 I269 D270 D326G266-G268 PolarHBondContact O-N 3.42Å; G266-I269 PolarHBondContact O-N 3.16Å; G266-D270 PolarHBondContact O-N 3.27Å; G266-D326 VanDerWaalsContact CA-OD1 3.29Å; G266-D326 WeakPolarHBondContact CA-OD1 3.19Å
267A90.8Very high95.9Very high37 Ų3728.4 Ų28.431%0.30614%0.139SC..THydrogen-bonded Turntrans-42.1115.2-165.100000115.2D270 D326 L328A267-D270 WeakPolarHBondContact CA-OD2 3.44Å; A267-D270 PolarHBondContact N-OD2 2.87Å; A267-D326 PolarHBondContact N-OD1 3.39Å; A267-D326 PolarHBondContact N-OD2 2.69Å; A267-L328 HydrophobicContact CB-CD1 4.47Å
268G92.3Very high96Very high14 Ų1422.7 Ų22.714%0.14411%0.112CC..THydrogen-bonded Turntrans92.16.5172.600000115.1T203 A204 G266 D270T203-G268 PolarHBondContact N-O 3.07Å; A204-G268 PolarHBondContact N-O 3.33Å; G266-G268 PolarHBondContact O-N 3.42Å; G268-D270 PolarHBondContact N-OD2 2.89Å
269I96.6Very high96Very high1 Ų121.8 Ų21.81%0.00511%0.109CC..THydrogen-bonded Turntrans-132.5-45.2169.9-50.1-179.6000111T203 V247 T249 G266 S271 Y272 Y273T203-I269 HydrophobicContact CG2-CG2 4.15Å; V247-I269 HydrophobicContact CG2-CG2 3.91Å; T249-I269 HydrophobicContact CG2-CG1 4.41Å; G266-I269 PolarHBondContact O-N 3.16Å; I269-S271 PolarHBondContact O-N 3.41Å; I269-S271 VanDerWaalsContact O-N 3.15Å; I269-Y272 WeakPolarHBondContact O-CB 3.4Å; I269-Y272 PolarHBondContact O-N 2.98Å; I269-Y273 HydrophobicContact CB-CE2 4.46Å; I269-Y273 HydrophobicContact CG2-CD2 4.01Å; I269-Y273 HydrophobicContact CG2-CE1 4.43Å; I269-Y273 HydrophobicContact CG2-CE2 3.39Å
270D96.3Very high96Very high18 Ų1821.3 Ų21.310%0.09610%0.099CC..Hα-helixtrans4.3-86.2161.342.246.4000116.7A204 V265 G266 A267 G268 Y272 Y273 E274 F331A204-D270 VanDerWaalsContact CB-OD1 3.23Å; A204-D270 WeakPolarHBondContact CB-OD1 3.39Å; V265-D270 VanDerWaalsContact O-CA 3.27Å; V265-D270 WeakPolarHBondContact O-CA 3.4Å; V265-D270 WeakPolarHBondContact O-CB 3.48Å; V265-D270 PolarHBondContact O-N 2.87Å; G266-D270 PolarHBondContact O-N 3.27Å; A267-D270 WeakPolarHBondContact CA-OD2 3.44Å; A267-D270 PolarHBondContact N-OD2 2.87Å; G268-D270 PolarHBondContact N-OD2 2.89Å; D270-Y272 VanDerWaalsContact C-N 3.31Å; D270-Y272 PolarHBondContact O-N 2.59Å; D270-Y273 PolarHBondContact O-N 2.81Å; D270-Y273 VanDerWaalsContact O-N 3.13Å; D270-E274 PolarHBondContact O-N 3.41Å; D270-F331 HydrophobicContact CB-CD1 4.42Å; D270-F331 HydrophobicContact CB-CE1 3.82Å; D270-F331 HydrophobicContact CB-CZ 4.03Å; D270-F331 VanDerWaalsContact O-CZ 3.31Å; D270-F331 WeakPolarHBondContact O-CZ 3.38Å
271S97.8Very high96Very high2 Ų217.2 Ų17.21%0.0149%0.088CC..Hα-helixtrans-72.9-15.4-16955.80000114.2A204 T208 I269 E274 Y275A204-S271 WeakPolarHBondContact CB-OG 3.4Å; T208-S271 WeakPolarHBondContact CG2-OG 3.27Å; T208-S271 VanDerWaalsContact OG1-C 3.31Å; T208-S271 WeakPolarHBondContact OG1-CB 3.5Å; T208-S271 PolarHBondContact OG1-OG 3.02Å; I269-S271 PolarHBondContact O-N 3.41Å; I269-S271 VanDerWaalsContact O-N 3.15Å; S271-E274 WeakPolarHBondContact O-CB 3.32Å; S271-E274 PolarHBondContact O-N 3.22Å; S271-Y275 WeakPolarHBondContact O-CB 3.42Å; S271-Y275 WeakPolarHBondContact O-CD1 3.4Å; S271-Y275 PolarHBondContact O-N 3.47Å
272Y98.3Very high96Very high0 Ų011.7 Ų11.70%07%0.067CC..Hα-helixtrans-65.5-41.3168.1162-100.8000111.2T203 T208 L233 L236 V247 I269 D270 E274 L276 H295T203-Y272 HydrophobicContact CG2-CD1 3.85Å; T203-Y272 HydrophobicContact CG2-CD2 4.42Å; T203-Y272 HydrophobicContact CG2-CE1 4.44Å; T203-Y272 HydrophobicContact CG2-CG 3.84Å; T208-Y272 PolarHBondContact OG1-N 3.12Å; L233-Y272 HydrophobicContact CD2-CD2 3.59Å; L233-Y272 HydrophobicContact CD2-CE2 3.55Å; L236-Y272 HydrophobicContact CB-CE2 3.9Å; L236-Y272 HydrophobicContact CD1-CD2 3.83Å; L236-Y272 HydrophobicContact CD1-CE2 3.84Å; V247-Y272 HydrophobicContact CG1-CE1 4.43Å; V247-Y272 HydrophobicContact CG2-CD1 4.26Å; V247-Y272 HydrophobicContact CG2-CE1 3.99Å; I269-Y272 WeakPolarHBondContact O-CB 3.4Å; I269-Y272 PolarHBondContact O-N 2.98Å; D270-Y272 VanDerWaalsContact C-N 3.31Å; D270-Y272 PolarHBondContact O-N 2.59Å; Y272-E274 VanDerWaalsContact C-N 3.34Å; Y272-L276 HydrophobicContact CE1-CD1 3.93Å; Y272-L276 HydrophobicContact CE2-CD1 4.13Å; Y272-L276 HydrophobicContact CE2-CG 4.4Å; Y272-L276 WeakPolarHBondContact O-CG 3.41Å; Y272-L276 PolarHBondContact O-N 2.89Å; Y272-H295 AromaticContact CE1-NE2 3.75Å; Y272-H295 AromaticContact CZ-NE2 3.8Å; Y272-H295 PolarHBondContact OH-NE2 3.01Å
273Y98.3Very high95.8Very high1 Ų111.4 Ų11.40%0.0047%0.066CC..Hα-helixtrans-70.3-35.4175.9-63.4-45.4000111.9V247 I269 D270 F292 H295 I299V247-Y273 HydrophobicContact CG2-CE1 4.13Å; V247-Y273 WeakPolarHBondContact CG2-OH 3.47Å; I269-Y273 HydrophobicContact CB-CE2 4.46Å; I269-Y273 HydrophobicContact CG2-CD2 4.01Å; I269-Y273 HydrophobicContact CG2-CE1 4.43Å; I269-Y273 HydrophobicContact CG2-CE2 3.39Å; D270-Y273 PolarHBondContact O-N 2.81Å; D270-Y273 VanDerWaalsContact O-N 3.13Å; Y273-F292 WeakPolarHBondContact O-CD2 3.43Å; Y273-H295 HydrophobicContact CD1-CB 3.89Å; Y273-H295 HydrophobicContact CE1-CB 3.64Å; Y273-H295 AromaticContact CE1-CG 3.66Å; Y273-H295 AromaticContact CE1-ND1 3.94Å; Y273-I299 HydrophobicContact CD1-CD1 4.26Å; Y273-I299 HydrophobicContact CD2-CD1 3.76Å; Y273-I299 HydrophobicContact CE1-CD1 4.17Å; Y273-I299 HydrophobicContact CE2-CD1 3.61Å; Y273-I299 HydrophobicContact CE2-CG1 4.28Å; Y273-I299 HydrophobicContact CG-CD1 4.07Å
274E98.4Very high95.4Very high3 Ų313.9 Ų13.91%0.0149%0.091CC..Hα-helixtrans-59.2-50.3174.1-157.4-154.6119.500111.5D270 S271 Y272 L276 L277 K278 F331 L335 T468D270-E274 PolarHBondContact O-N 3.41Å; S271-E274 WeakPolarHBondContact O-CB 3.32Å; S271-E274 PolarHBondContact O-N 3.22Å; Y272-E274 VanDerWaalsContact C-N 3.34Å; E274-L276 VanDerWaalsContact C-N 3.3Å; E274-L276 PolarHBondContact O-N 2.73Å; E274-L277 PolarHBondContact O-N 3.33Å; E274-K278 HydrophobicContact CG-CD 3.9Å; E274-K278 PolarHBondContact O-N 2.99Å; E274-K278 WeakPolarHBondContact OE1-CD 3.46Å; E274-K278 WeakPolarHBondContact OE1-CE 3.48Å; E274-K278 IonicContact OE1-NZ 3.79Å; E274-K278 PolarHBondContact OE1-NZ 3.24Å; E274-F331 HydrophobicContact CB-CE2 3.92Å; E274-F331 HydrophobicContact CG-CD2 4.27Å; E274-F331 HydrophobicContact CG-CE2 4.09Å; E274-L335 HydrophobicContact CB-CD1 4.48Å; E274-L335 HydrophobicContact CB-CD2 4.49Å; E274-L335 HydrophobicContact CG-CD1 4.21Å; E274-T468 VanDerWaalsContact OE1-CA 3.28Å; E274-T468 WeakPolarHBondContact OE1-CA 3.26Å; E274-T468 PolarHBondContact OE1-N 3.17Å; E274-T468 VanDerWaalsContact OE2-CB 3.27Å; E274-T468 WeakPolarHBondContact OE2-CB 3.17Å; E274-T468 PolarHBondContact OE2-OG1 3.04Å
275Y98.4Very high95.1Very high0 Ų015.9 Ų15.90%010%0.101CC..Hα-helixtrans-71.5-25.5-175.4-84.132.7000112.1T208 I210 L211 E212 S271 L277 A279 T467 T468T208-Y275 HydrophobicContact CG2-CD1 3.94Å; T208-Y275 HydrophobicContact CG2-CD2 3.73Å; T208-Y275 HydrophobicContact CG2-CE1 3.67Å; T208-Y275 HydrophobicContact CG2-CE2 3.42Å; T208-Y275 VanDerWaalsContact CG2-CE2 3.42Å; T208-Y275 HydrophobicContact CG2-CG 3.99Å; I210-Y275 HydrophobicContact CG2-CD2 3.86Å; I210-Y275 HydrophobicContact CG2-CG 4.36Å; L211-Y275 HydrophobicContact CB-CD2 4.29Å; L211-Y275 HydrophobicContact CB-CE2 3.83Å; L211-Y275 HydrophobicContact CD1-CD1 3.82Å; L211-Y275 HydrophobicContact CD1-CD2 4.15Å; L211-Y275 HydrophobicContact CD1-CE1 3.49Å; L211-Y275 VanDerWaalsContact CD1-CE1 3.49Å; L211-Y275 HydrophobicContact CD1-CE2 3.86Å; L211-Y275 HydrophobicContact CD1-CG 4.13Å; L211-Y275 HydrophobicContact CG-CD1 4.22Å; L211-Y275 HydrophobicContact CG-CD2 3.7Å; L211-Y275 HydrophobicContact CG-CE1 4.14Å; L211-Y275 HydrophobicContact CG-CE2 3.61Å; L211-Y275 HydrophobicContact CG-CG 4Å; E212-Y275 PolarHBondContact OE1-OH 3.1Å; E212-Y275 WeakPolarHBondContact OE2-CE2 3.33Å; S271-Y275 WeakPolarHBondContact O-CB 3.42Å; S271-Y275 WeakPolarHBondContact O-CD1 3.4Å; S271-Y275 PolarHBondContact O-N 3.47Å; Y275-L277 VanDerWaalsContact C-N 3.33Å; Y275-L277 PolarHBondContact O-N 3.17Å; Y275-A279 WeakPolarHBondContact O-CB 3.33Å; Y275-A279 PolarHBondContact O-N 3.02Å; Y275-T467 WeakPolarHBondContact OH-CB 3.44Å; Y275-T468 HydrophobicContact CE1-CG2 4.31Å; Y275-T468 PolarHBondContact OH-N 3.49Å
276L98.3Very high95Very high1 Ų119.9 Ų19.91%0.00512%0.123CC..Hα-helixtrans-66.7-29169.1-69.3176.1000113.4L233 Y272 E274 F288 R291 F292L233-L276 HydrophobicContact CD2-CD2 4.36Å; Y272-L276 HydrophobicContact CE1-CD1 3.93Å; Y272-L276 HydrophobicContact CE2-CD1 4.13Å; Y272-L276 HydrophobicContact CE2-CG 4.4Å; Y272-L276 WeakPolarHBondContact O-CG 3.41Å; Y272-L276 PolarHBondContact O-N 2.89Å; E274-L276 VanDerWaalsContact C-N 3.3Å; E274-L276 PolarHBondContact O-N 2.73Å; L276-F288 HydrophobicContact CD2-CD1 4.03Å; L276-F288 CarbonylContact O-C 3.54Å; L276-F288 WeakPolarHBondContact O-CB 3.45Å; L276-R291 HydrophobicContact CD1-CB 4.16Å; L276-R291 HydrophobicContact CD2-CB 4.12Å; L276-F292 HydrophobicContact CB-CB 3.86Å
277L97.8Very high95Very high8 Ų822.7 Ų22.74%0.04214%0.137CC..Hα-helixtrans-85.3-46.7171.5-176.460.3000111.5E274 Y275 A279 Y280 I281 L289 F292 L335 L338 K339E274-L277 PolarHBondContact O-N 3.33Å; Y275-L277 VanDerWaalsContact C-N 3.33Å; Y275-L277 PolarHBondContact O-N 3.17Å; L277-A279 VanDerWaalsContact C-N 3.33Å; L277-A279 PolarHBondContact O-N 2.82Å; L277-Y280 WeakPolarHBondContact O-CB 3.48Å; L277-Y280 PolarHBondContact O-N 3.23Å; L277-I281 HydrophobicContact CG-CD1 4.12Å; L277-I281 PolarHBondContact O-N 2.73Å; L277-L289 HydrophobicContact CD1-CD1 4.12Å; L277-F292 HydrophobicContact CB-CD1 3.96Å; L277-F292 HydrophobicContact CB-CD2 4.07Å; L277-F292 HydrophobicContact CB-CE1 3.98Å; L277-F292 HydrophobicContact CB-CE2 4.13Å; L277-F292 HydrophobicContact CB-CG 3.99Å; L277-F292 HydrophobicContact CB-CZ 4.08Å; L277-F292 HydrophobicContact CD1-CD1 3.79Å; L277-F292 HydrophobicContact CD1-CE1 3.84Å; L277-F292 HydrophobicContact CD2-CD1 4.46Å; L277-F292 HydrophobicContact CD2-CE1 3.76Å; L277-F292 HydrophobicContact CD2-CZ 3.91Å; L277-F292 HydrophobicContact CG-CD1 4.27Å; L277-F292 HydrophobicContact CG-CE1 4.06Å; L277-F292 HydrophobicContact CG-CZ 4.43Å; L277-L335 HydrophobicContact CB-CD1 4.03Å; L277-L335 HydrophobicContact CD2-CD1 3.81Å; L277-L338 HydrophobicContact CD2-CB 3.72Å; L277-K339 HydrophobicContact CD2-CB 4.37Å
278K97.8Very high95.3Very high2 Ų221 Ų211%0.00912%0.122CC..Hα-helixtrans-66.4-31.4-177.1-71.5179.2171.6-1780112.7L211 E274 I281 L282 V465 F466 T467L211-K278 HydrophobicContact CD1-CB 3.82Å; L211-K278 HydrophobicContact CD1-CD 4.23Å; L211-K278 HydrophobicContact CD2-CB 4.09Å; E274-K278 HydrophobicContact CG-CD 3.9Å; E274-K278 PolarHBondContact O-N 2.99Å; E274-K278 WeakPolarHBondContact OE1-CD 3.46Å; E274-K278 WeakPolarHBondContact OE1-CE 3.48Å; E274-K278 IonicContact OE1-NZ 3.79Å; E274-K278 PolarHBondContact OE1-NZ 3.24Å; K278-I281 PolarHBondContact O-N 2.73Å; K278-L282 WeakPolarHBondContact O-CB 3.35Å; K278-L282 PolarHBondContact O-N 3.28Å; K278-V465 HydrophobicContact CB-CG2 4.12Å; K278-V465 HydrophobicContact CD-CG2 4.32Å; K278-V465 HydrophobicContact CG-CG2 4.02Å; K278-F466 WeakPolarHBondContact CD-O 3.37Å; K278-F466 WeakPolarHBondContact CE-O 3.44Å; K278-F466 PolarHBondContact NZ-O 3.34Å; K278-T467 PolarHBondContact NZ-O 3.1Å
279A96.4Very high95.4Very high0 Ų021.6 Ų21.60%012%0.122CC..Hα-helixtrans-71.2-30.3174.600000112.8I210 L211 Y275 L277 L283 F288I210-A279 HydrophobicContact CG1-CB 4.33Å; I210-A279 HydrophobicContact CG2-CB 3.91Å; L211-A279 HydrophobicContact CD2-CB 4.03Å; Y275-A279 WeakPolarHBondContact O-CB 3.33Å; Y275-A279 PolarHBondContact O-N 3.02Å; L277-A279 VanDerWaalsContact C-N 3.33Å; L277-A279 PolarHBondContact O-N 2.82Å; A279-L283 HydrophobicContact CB-CD1 4.46Å; A279-L283 VanDerWaalsContact O-CB 3.24Å; A279-L283 WeakPolarHBondContact O-CB 3.44Å; A279-L283 WeakPolarHBondContact O-CG 3.42Å; A279-L283 PolarHBondContact O-N 3.23Å; A279-F288 HydrophobicContact CB-CB 4.49Å; A279-F288 HydrophobicContact CB-CD1 4.4Å; A279-F288 HydrophobicContact CB-CD2 3.83Å; A279-F288 HydrophobicContact CB-CE2 4.08Å; A279-F288 HydrophobicContact CB-CG 4.02Å; A279-F288 HydrophobicContact CB-CZ 4.47Å
280Y95.6Very high95.5Very high61 Ų6127 Ų2724%0.23915%0.147CC..Hα-helixtrans-63-47.3168169.5-110000110.9L277 L282 G284 D285 D286 L289L277-Y280 WeakPolarHBondContact O-CB 3.48Å; L277-Y280 PolarHBondContact O-N 3.23Å; Y280-L282 VanDerWaalsContact C-N 3.33Å; Y280-L282 PolarHBondContact O-N 3.35Å; Y280-G284 WeakPolarHBondContact O-CA 3.5Å; Y280-G284 PolarHBondContact O-N 3.05Å; Y280-D285 WeakPolarHBondContact CD2-O 3.39Å; Y280-D286 WeakPolarHBondContact CE2-OD1 3.17Å; Y280-L289 HydrophobicContact CD1-CB 4.04Å; Y280-L289 HydrophobicContact CD1-CD1 4.27Å; Y280-L289 HydrophobicContact CD1-CD2 4.19Å; Y280-L289 HydrophobicContact CD1-CG 4.38Å; Y280-L289 HydrophobicContact CD2-CB 3.73Å; Y280-L289 HydrophobicContact CD2-CD2 4.46Å; Y280-L289 HydrophobicContact CE1-CB 4.41Å; Y280-L289 HydrophobicContact CE1-CD1 4.5Å; Y280-L289 HydrophobicContact CE1-CD2 3.76Å; Y280-L289 HydrophobicContact CE1-CG 4.43Å; Y280-L289 HydrophobicContact CE2-CB 4.12Å; Y280-L289 HydrophobicContact CE2-CD2 4.05Å; Y280-L289 HydrophobicContact CG-CB 3.66Å; Y280-L289 HydrophobicContact CG-CG 4.49Å
281I94.1Very high95.5Very high64 Ų6426.9 Ų26.933%0.32815%0.145SC..Hα-helixtrans-60.9-40.9179-64.9167.8000111.5L277 K278 V465 L475L277-I281 HydrophobicContact CG-CD1 4.12Å; L277-I281 PolarHBondContact O-N 2.73Å; K278-I281 PolarHBondContact O-N 2.73Å; I281-V465 HydrophobicContact CG2-CB 4.5Å; I281-V465 HydrophobicContact CG2-CG2 4.32Å; I281-L475 HydrophobicContact CG2-CD2 3.78Å
282L93.8Very high95.5Very high1 Ų126.9 Ų26.91%0.00515%0.145CC..Hα-helixtrans-79.1-34.3-177.9-174.257.6000114.3L211 K278 Y280 V465 L473 L477 S478L211-L282 HydrophobicContact CB-CD2 4.38Å; L211-L282 HydrophobicContact CD2-CB 4.35Å; L211-L282 HydrophobicContact CD2-CD2 3.89Å; K278-L282 WeakPolarHBondContact O-CB 3.35Å; K278-L282 PolarHBondContact O-N 3.28Å; Y280-L282 VanDerWaalsContact C-N 3.33Å; Y280-L282 PolarHBondContact O-N 3.35Å; L282-V465 HydrophobicContact CB-CG1 4.19Å; L282-V465 HydrophobicContact CD1-CG1 3.95Å; L282-V465 HydrophobicContact CD2-CG1 4.34Å; L282-V465 HydrophobicContact CG-CG1 4.38Å; L282-L473 HydrophobicContact CD1-CB 4.49Å; L282-L473 HydrophobicContact CD2-CD1 4.09Å; L282-L477 HydrophobicContact CD1-CB 4.11Å; L282-L477 HydrophobicContact CD1-CD1 4.22Å; L282-S478 WeakPolarHBondContact O-CA 3.31Å; L282-S478 VanDerWaalsContact O-CB 3.31Å; L282-S478 WeakPolarHBondContact O-CB 3.37Å; L282-S478 PolarHBondContact O-N 3.04Å
283L91.1Very high95.5Very high21 Ų2129.5 Ų29.511%0.1116%0.159CC..Hα-helixtrans-115.2-10.5-168.2-52.5176.2000114.3I210 A214 A279 D285 F288I210-L283 HydrophobicContact CG1-CD1 4.45Å; A214-L283 HydrophobicContact CB-CD1 3.86Å; A214-L283 HydrophobicContact CB-CD2 3.82Å; A214-L283 HydrophobicContact CB-CG 4.43Å; A279-L283 HydrophobicContact CB-CD1 4.46Å; A279-L283 VanDerWaalsContact O-CB 3.24Å; A279-L283 WeakPolarHBondContact O-CB 3.44Å; A279-L283 WeakPolarHBondContact O-CG 3.42Å; A279-L283 PolarHBondContact O-N 3.23Å; L283-D285 VanDerWaalsContact C-N 3.26Å; L283-D285 PolarHBondContact O-N 3.26Å; L283-F288 HydrophobicContact CD1-CE2 3.99Å
284G88.2Confident95.5Very high51 Ų5132 Ų3253%0.52617%0.172SC..  trans68.618-179.200000115Y280Y280-G284 WeakPolarHBondContact O-CA 3.5Å; Y280-G284 PolarHBondContact O-N 3.05Å
285D89.6Confident95.4Very high43 Ų4331.9 Ų31.923%0.2317%0.172CC..  trans-96.7102.4-174.3179.9-3000111.8R230 Y280 L283 L287 F288R230-D285 IonicContact CZ-OD2 2.75Å; R230-D285 IonicContact NH1-OD2 3.34Å; R230-D285 PolarHBondContact NH1-OD2 3.35Å; R230-D285 IonicContact NH2-OD2 2.73Å; R230-D285 PolarHBondContact NH2-OD2 3.04Å; Y280-D285 WeakPolarHBondContact CD2-O 3.39Å; L283-D285 VanDerWaalsContact C-N 3.26Å; L283-D285 PolarHBondContact O-N 3.26Å; D285-L287 PolarHBondContact O-N 3.1Å; D285-L287 WeakPolarHBondContact OD1-CB 3.38Å; D285-L287 PolarHBondContact OD1-N 3.36Å; D285-F288 HydrophobicContact CB-CD2 3.83Å; D285-F288 HydrophobicContact CB-CE2 4.08Å; D285-F288 PolarHBondContact O-N 3.48Å
286D91.4Very high95.4Very high86 Ų8632.5 Ų32.546%0.4617%0.174SC..Hα-helixtrans-52.6-21.9-179.1-67.5-49000114.2Y280 F288 L289 Q290Y280-D286 WeakPolarHBondContact CE2-OD1 3.17Å; D286-F288 VanDerWaalsContact C-N 3.29Å; D286-F288 PolarHBondContact O-N 3.08Å; D286-L289 PolarHBondContact O-N 2.72Å; D286-Q290 WeakPolarHBondContact O-CB 3.28Å; D286-Q290 PolarHBondContact O-N 2.8Å
287L94.5Very high95.3Very high63 Ų6335.3 Ų35.333%0.3320%0.198SC..Hα-helixtrans-62.1-37.7177-175.957.5000111.6D285 R291D285-L287 PolarHBondContact O-N 3.1Å; D285-L287 WeakPolarHBondContact OD1-CB 3.38Å; D285-L287 PolarHBondContact OD1-N 3.36Å; L287-R291 WeakPolarHBondContact O-CG 3.45Å; L287-R291 PolarHBondContact O-N 3.08Å; L287-R291 VanDerWaalsContact O-N 3.11Å
288F96.2Very high95.2Very high1 Ų135.4 Ų35.40%0.00420%0.199CC..Hα-helixtrans-68.3-44.2176.1-64.3-59.7000111.1I210 L233 L276 A279 L283 D285 D286 Q290 R291 F292I210-F288 HydrophobicContact CD1-CZ 4.43Å; I210-F288 HydrophobicContact CG1-CZ 4.11Å; L233-F288 HydrophobicContact CD1-CD1 4.46Å; L233-F288 HydrophobicContact CD1-CE1 3.79Å; L276-F288 HydrophobicContact CD2-CD1 4.03Å; L276-F288 CarbonylContact O-C 3.54Å; L276-F288 WeakPolarHBondContact O-CB 3.45Å; A279-F288 HydrophobicContact CB-CB 4.49Å; A279-F288 HydrophobicContact CB-CD1 4.4Å; A279-F288 HydrophobicContact CB-CD2 3.83Å; A279-F288 HydrophobicContact CB-CE2 4.08Å; A279-F288 HydrophobicContact CB-CG 4.02Å; A279-F288 HydrophobicContact CB-CZ 4.47Å; L283-F288 HydrophobicContact CD1-CE2 3.99Å; D285-F288 HydrophobicContact CB-CD2 3.83Å; D285-F288 HydrophobicContact CB-CE2 4.08Å; D285-F288 PolarHBondContact O-N 3.48Å; D286-F288 VanDerWaalsContact C-N 3.29Å; D286-F288 PolarHBondContact O-N 3.08Å; F288-Q290 PolarHBondContact O-N 3.18Å; F288-R291 PolarHBondContact O-N 2.75Å; F288-F292 WeakPolarHBondContact O-CB 3.39Å; F288-F292 PolarHBondContact O-N 3.29Å
289L95.5Very high95.2Very high27 Ų2735.4 Ų35.414%0.14120%0.199CC..Hα-helixtrans-60.7-42175.2178.962.4000112.3L277 Y280 D286 F292 N293 W503L277-L289 HydrophobicContact CD1-CD1 4.12Å; Y280-L289 HydrophobicContact CD1-CB 4.04Å; Y280-L289 HydrophobicContact CD1-CD1 4.27Å; Y280-L289 HydrophobicContact CD1-CD2 4.19Å; Y280-L289 HydrophobicContact CD1-CG 4.38Å; Y280-L289 HydrophobicContact CD2-CB 3.73Å; Y280-L289 HydrophobicContact CD2-CD2 4.46Å; Y280-L289 HydrophobicContact CE1-CB 4.41Å; Y280-L289 HydrophobicContact CE1-CD1 4.5Å; Y280-L289 HydrophobicContact CE1-CD2 3.76Å; Y280-L289 HydrophobicContact CE1-CG 4.43Å; Y280-L289 HydrophobicContact CE2-CB 4.12Å; Y280-L289 HydrophobicContact CE2-CD2 4.05Å; Y280-L289 HydrophobicContact CG-CB 3.66Å; Y280-L289 HydrophobicContact CG-CG 4.49Å; D286-L289 PolarHBondContact O-N 2.72Å; L289-F292 HydrophobicContact CD1-CD1 4.47Å; L289-F292 PolarHBondContact O-N 3.23Å; L289-N293 WeakPolarHBondContact CD1-ND2 3.42Å; L289-N293 WeakPolarHBondContact O-CB 3.18Å; L289-N293 VanDerWaalsContact O-CG 3.3Å; L289-N293 PolarHBondContact O-N 3.36Å; L289-N293 PolarHBondContact O-ND2 2.61Å; L289-W503 HydrophobicContact CD2-CZ3 3.9Å
290Q97Very high95.1Very high115 Ų11537.8 Ų37.854%0.53721%0.211SC..Hα-helixtrans-60.9-45.9176.6-174.5-172.887.100111.2D286 F288 N293 I294D286-Q290 WeakPolarHBondContact O-CB 3.28Å; D286-Q290 PolarHBondContact O-N 2.8Å; F288-Q290 PolarHBondContact O-N 3.18Å; Q290-N293 PolarHBondContact O-N 3.26Å; Q290-I294 HydrophobicContact CG-CD1 4.07Å; Q290-I294 WeakPolarHBondContact O-CG1 3.33Å; Q290-I294 PolarHBondContact O-N 2.97Å; Q290-I294 VanDerWaalsContact O-N 3.13Å
291R97.5Very high95Very high14 Ų1441.5 Ų41.55%0.05323%0.228CC..Hα-helixtrans-62.8-48.1177.3-69.4174.9-177.4-174.82.9111.5D234 W237 L276 L287 F288 N293 I294 H295D234-R291 IonicContact OD1-CZ 3.63Å; D234-R291 IonicContact OD1-NH1 2.8Å; D234-R291 PolarHBondContact OD1-NH1 3.27Å; D234-R291 IonicContact OD1-NH2 2.65Å; D234-R291 PolarHBondContact OD1-NH2 3.17Å; W237-R291 HydrophobicContact CD2-CB 4.36Å; W237-R291 HydrophobicContact CD2-CG 3.59Å; W237-R291 HydrophobicContact CE3-CB 3.9Å; W237-R291 HydrophobicContact CE3-CG 3.65Å; W237-R291 HydrophobicContact CG-CG 4.15Å; W237-R291 HydrophobicContact CH2-CB 4.27Å; W237-R291 HydrophobicContact CH2-CG 4Å; W237-R291 HydrophobicContact CZ2-CG 3.94Å; W237-R291 HydrophobicContact CZ3-CB 3.86Å; W237-R291 HydrophobicContact CZ3-CG 3.87Å; L276-R291 HydrophobicContact CD1-CB 4.16Å; L276-R291 HydrophobicContact CD2-CB 4.12Å; L287-R291 WeakPolarHBondContact O-CG 3.45Å; L287-R291 PolarHBondContact O-N 3.08Å; L287-R291 VanDerWaalsContact O-N 3.11Å; F288-R291 PolarHBondContact O-N 2.75Å; R291-N293 PolarHBondContact O-N 2.9Å; R291-I294 PolarHBondContact O-N 2.96Å; R291-H295 PolarHBondContact O-CD2 3.13Å; R291-H295 VanDerWaalsContact O-CD2 3.25Å; R291-H295 PolarHBondContact O-N 2.91Å
292F98.1Very high95.1Very high2 Ų240 Ų401%0.00922%0.218CC..Hα-helixtrans-55.7-50.4175.5174.9-114.1000111.6Y273 L276 L277 F288 L289 I294 H295 Y296 L335 K339Y273-F292 WeakPolarHBondContact O-CD2 3.43Å; L276-F292 HydrophobicContact CB-CB 3.86Å; L277-F292 HydrophobicContact CB-CD1 3.96Å; L277-F292 HydrophobicContact CB-CD2 4.07Å; L277-F292 HydrophobicContact CB-CE1 3.98Å; L277-F292 HydrophobicContact CB-CE2 4.13Å; L277-F292 HydrophobicContact CB-CG 3.99Å; L277-F292 HydrophobicContact CB-CZ 4.08Å; L277-F292 HydrophobicContact CD1-CD1 3.79Å; L277-F292 HydrophobicContact CD1-CE1 3.84Å; L277-F292 HydrophobicContact CD2-CD1 4.46Å; L277-F292 HydrophobicContact CD2-CE1 3.76Å; L277-F292 HydrophobicContact CD2-CZ 3.91Å; L277-F292 HydrophobicContact CG-CD1 4.27Å; L277-F292 HydrophobicContact CG-CE1 4.06Å; L277-F292 HydrophobicContact CG-CZ 4.43Å; F288-F292 WeakPolarHBondContact O-CB 3.39Å; F288-F292 PolarHBondContact O-N 3.29Å; L289-F292 HydrophobicContact CD1-CD1 4.47Å; L289-F292 PolarHBondContact O-N 3.23Å; F292-I294 VanDerWaalsContact C-N 3.31Å; F292-I294 PolarHBondContact O-N 2.79Å; F292-H295 PolarHBondContact O-N 3.38Å; F292-Y296 HydrophobicContact CE2-CD2 4.47Å; F292-Y296 HydrophobicContact CZ-CD2 4.1Å; F292-Y296 VanDerWaalsContact O-CB 3.32Å; F292-Y296 WeakPolarHBondContact O-CB 3.34Å; F292-Y296 PolarHBondContact O-N 2.73Å; F292-L335 HydrophobicContact CE2-CD1 4.42Å; F292-L335 HydrophobicContact CE2-CD2 3.94Å; F292-L335 HydrophobicContact CE2-CG 4.17Å; F292-L335 HydrophobicContact CZ-CD1 4.46Å; F292-L335 HydrophobicContact CZ-CD2 4.44Å; F292-L335 HydrophobicContact CZ-CG 4.19Å; F292-K339 HydrophobicContact CE1-CB 4.02Å; F292-K339 HydrophobicContact CE1-CD 3.68Å; F292-K339 HydrophobicContact CE1-CG 4.01Å; F292-K339 HydrophobicContact CZ-CB 4.25Å; F292-K339 HydrophobicContact CZ-CD 4.08Å
293N97.5Very high95.1Very high55 Ų5540 Ų4029%0.29422%0.218SC..Hα-helixtrans-61.1-37-179.2-78.5-32.9000113L289 Q290 R291 A297 K339L289-N293 WeakPolarHBondContact CD1-ND2 3.42Å; L289-N293 WeakPolarHBondContact O-CB 3.18Å; L289-N293 VanDerWaalsContact O-CG 3.3Å; L289-N293 PolarHBondContact O-N 3.36Å; L289-N293 PolarHBondContact O-ND2 2.61Å; Q290-N293 PolarHBondContact O-N 3.26Å; R291-N293 PolarHBondContact O-N 2.9Å; N293-A297 WeakPolarHBondContact O-CB 3.46Å; N293-A297 PolarHBondContact O-N 2.92Å; N293-K339 PolarHBondContact OD1-NZ 3.21Å
294I97.7Very high95.1Very high55 Ų5539.6 Ų39.628%0.28222%0.217SC..Hα-helixtrans-70.2-39.8177.2-71.2166.5000111.7W237 N245 Q290 R291 F292 S298W237-I294 HydrophobicContact CH2-CB 3.91Å; W237-I294 HydrophobicContact CH2-CD1 3.74Å; W237-I294 HydrophobicContact CH2-CG1 4.42Å; W237-I294 HydrophobicContact CH2-CG2 3.8Å; W237-I294 HydrophobicContact CZ2-CD1 4.22Å; W237-I294 HydrophobicContact CZ3-CB 4.37Å; W237-I294 HydrophobicContact CZ3-CG2 4.22Å; N245-I294 HydrophobicContact CB-CG2 3.79Å; Q290-I294 HydrophobicContact CG-CD1 4.07Å; Q290-I294 WeakPolarHBondContact O-CG1 3.33Å; Q290-I294 PolarHBondContact O-N 2.97Å; Q290-I294 VanDerWaalsContact O-N 3.13Å; R291-I294 PolarHBondContact O-N 2.96Å; F292-I294 VanDerWaalsContact C-N 3.31Å; F292-I294 PolarHBondContact O-N 2.79Å; I294-S298 PolarHBondContact O-N 3.36Å; I294-S298 PolarHBondContact O-OG 3.41Å
295H97.9Very high94.9Very high0 Ų042 Ų420%022%0.215CC..Hα-helixtrans-66.8-46.8172.1-72.9-55.9000111.3W237 N245 Y272 Y273 R291 F292 A297 S298 I299W237-H295 AromaticContact CE3-NE2 3.46Å; W237-H295 AromaticContact CZ3-CD2 3.96Å; W237-H295 AromaticContact CZ3-NE2 3.58Å; N245-H295 PolarHBondContact O-CE1 2.85Å; N245-H295 VanDerWaalsContact O-CE1 3.25Å; N245-H295 PolarHBondContact O-ND1 3.44Å; Y272-H295 AromaticContact CE1-NE2 3.75Å; Y272-H295 AromaticContact CZ-NE2 3.8Å; Y272-H295 PolarHBondContact OH-NE2 3.01Å; Y273-H295 HydrophobicContact CD1-CB 3.89Å; Y273-H295 HydrophobicContact CE1-CB 3.64Å; Y273-H295 AromaticContact CE1-CG 3.66Å; Y273-H295 AromaticContact CE1-ND1 3.94Å; R291-H295 PolarHBondContact O-CD2 3.13Å; R291-H295 VanDerWaalsContact O-CD2 3.25Å; R291-H295 PolarHBondContact O-N 2.91Å; F292-H295 PolarHBondContact O-N 3.38Å; H295-A297 PolarHBondContact O-N 3.06Å; H295-S298 CarbonylContact O-C 3.59Å; H295-S298 WeakPolarHBondContact O-CA 3.27Å; H295-S298 WeakPolarHBondContact O-CB 3.36Å; H295-S298 PolarHBondContact O-N 3.28Å; H295-I299 WeakPolarHBondContact O-CG1 3.12Å; H295-I299 PolarHBondContact O-N 3.07Å
296Y97.1Very high94.1Very high12 Ų1243.6 Ų43.65%0.04723%0.228CC..Hα-helixtrans-57.3-48.2179.1-170.6-93.6000112.6F292 S298 I299 M300 F332 Q336 K339 D341F292-Y296 HydrophobicContact CE2-CD2 4.47Å; F292-Y296 HydrophobicContact CZ-CD2 4.1Å; F292-Y296 VanDerWaalsContact O-CB 3.32Å; F292-Y296 WeakPolarHBondContact O-CB 3.34Å; F292-Y296 PolarHBondContact O-N 2.73Å; Y296-S298 PolarHBondContact O-N 3.06Å; Y296-S298 VanDerWaalsContact O-N 3.1Å; Y296-I299 PolarHBondContact O-N 2.8Å; Y296-M300 HydrophobicContact CD1-CG 3.86Å; Y296-M300 HydrophobicContact CE1-CG 3.38Å; Y296-M300 HydrophobicContact CE1-SD 4.31Å; Y296-M300 HydrophobicContact CE2-CG 4.11Å; Y296-M300 HydrophobicContact CE2-SD 4.27Å; Y296-M300 HydrophobicContact CG-CG 4.43Å; Y296-M300 VanDerWaalsContact CZ-CG 3.5Å; Y296-M300 WeakPolarHBondContact O-CB 3.19Å; Y296-M300 WeakPolarHBondContact O-CG 3.33Å; Y296-M300 PolarHBondContact O-N 3.18Å; Y296-F332 HydrophobicContact CD2-CZ 4.06Å; Y296-F332 HydrophobicContact CE2-CE1 4.26Å; Y296-F332 AromaticContact CE2-CZ 3.75Å; Y296-F332 HydrophobicContact CE2-CZ 3.75Å; Y296-Q336 HydrophobicContact CE2-CG 3.86Å; Y296-Q336 WeakPolarHBondContact OH-CG 3.18Å; Y296-Q336 PolarHBondContact OH-NE2 3.09Å; Y296-K339 HydrophobicContact CD1-CD 3.54Å; Y296-K339 HydrophobicContact CD2-CD 3.84Å; Y296-K339 HydrophobicContact CE1-CD 3.63Å; Y296-K339 HydrophobicContact CE2-CD 3.97Å; Y296-K339 HydrophobicContact CG-CD 3.64Å; Y296-D341 WeakPolarHBondContact CE1-OD2 3.33Å; Y296-D341 PolarHBondContact OH-OD2 2.75Å
297A96.4Very high93.4Very high61 Ų6140.9 Ų40.950%0.50422%0.215SC..Hα-helixtrans-60.3-21.9175.700000113.2N293 H295 K301N293-A297 WeakPolarHBondContact O-CB 3.46Å; N293-A297 PolarHBondContact O-N 2.92Å; H295-A297 PolarHBondContact O-N 3.06Å; A297-K301 VanDerWaalsContact O-CB 3.28Å; A297-K301 WeakPolarHBondContact O-CB 3.15Å
298S96.7Very high93.1Very high10 Ų1039.3 Ų39.37%0.0721%0.207CC..Hα-helixtrans-90-39.4177.7-54.80000112.1S244 I294 H295 Y296 K301 Y302S244-S298 WeakPolarHBondContact O-CB 3.48Å; S244-S298 PolarHBondContact O-OG 2.88Å; I294-S298 PolarHBondContact O-N 3.36Å; I294-S298 PolarHBondContact O-OG 3.41Å; H295-S298 CarbonylContact O-C 3.59Å; H295-S298 WeakPolarHBondContact O-CA 3.27Å; H295-S298 WeakPolarHBondContact O-CB 3.36Å; H295-S298 PolarHBondContact O-N 3.28Å; Y296-S298 PolarHBondContact O-N 3.06Å; Y296-S298 VanDerWaalsContact O-N 3.1Å; S298-K301 PolarHBondContact O-N 3.05Å; S298-Y302 VanDerWaalsContact O-CD2 3.23Å; S298-Y302 WeakPolarHBondContact O-CD2 3.28Å; S298-Y302 PolarHBondContact O-N 3.24Å
299I96.6Very high92.9Very high1 Ų139.4 Ų39.41%0.00521%0.207CC..Hα-helixtrans-57.3-51.9170.4-66.5160.8000109.7V265 Y273 H295 Y296 K301 Y302 I303 S304 F332V265-I299 HydrophobicContact CG1-CD1 4.18Å; V265-I299 HydrophobicContact CG1-CG1 4.34Å; V265-I299 HydrophobicContact CG1-CG2 3.54Å; Y273-I299 HydrophobicContact CD1-CD1 4.26Å; Y273-I299 HydrophobicContact CD2-CD1 3.76Å; Y273-I299 HydrophobicContact CE1-CD1 4.17Å; Y273-I299 HydrophobicContact CE2-CD1 3.61Å; Y273-I299 HydrophobicContact CE2-CG1 4.28Å; Y273-I299 HydrophobicContact CG-CD1 4.07Å; H295-I299 WeakPolarHBondContact O-CG1 3.12Å; H295-I299 PolarHBondContact O-N 3.07Å; Y296-I299 PolarHBondContact O-N 2.8Å; I299-K301 PolarHBondContact O-N 3.3Å; I299-K301 VanDerWaalsContact O-N 3.11Å; I299-Y302 PolarHBondContact O-N 3.36Å; I299-I303 HydrophobicContact CB-CD1 4.5Å; I299-I303 HydrophobicContact CG1-CD1 4.11Å; I299-I303 HydrophobicContact CG2-CB 4.2Å; I299-I303 HydrophobicContact CG2-CG2 4.34Å; I299-I303 PolarHBondContact O-N 3.34Å; I299-S304 PolarHBondContact O-N 2.62Å; I299-F332 HydrophobicContact CD1-CE2 4.32Å; I299-F332 HydrophobicContact CD1-CZ 4.38Å; I299-F332 HydrophobicContact CG2-CE1 4.2Å; I299-F332 HydrophobicContact CG2-CE2 4.48Å; I299-F332 HydrophobicContact CG2-CZ 3.73Å
300M94.4Very high92.7Very high50 Ų5038.9 Ų38.925%0.24620%0.204CC..Hα-helixtrans-67-11.4179.4-63.9-51.3-6600114.4Y296 F332 Q336 P344Y296-M300 HydrophobicContact CD1-CG 3.86Å; Y296-M300 HydrophobicContact CE1-CG 3.38Å; Y296-M300 HydrophobicContact CE1-SD 4.31Å; Y296-M300 HydrophobicContact CE2-CG 4.11Å; Y296-M300 HydrophobicContact CE2-SD 4.27Å; Y296-M300 HydrophobicContact CG-CG 4.43Å; Y296-M300 VanDerWaalsContact CZ-CG 3.5Å; Y296-M300 WeakPolarHBondContact O-CB 3.19Å; Y296-M300 WeakPolarHBondContact O-CG 3.33Å; Y296-M300 PolarHBondContact O-N 3.18Å; M300-F332 HydrophobicContact SD-CE1 4.49Å; M300-Q336 PolarHBondContact SD-NE2 3.08Å; M300-P344 HydrophobicContact CE-CB 3.81Å; M300-P344 HydrophobicContact CE-CG 3.75Å
301K94.6Very high92.5Very high140 Ų14033.7 Ų33.761%0.60918%0.181SC*.Hα-helixtrans-99.3-30.5178.3-176.9-176.7177-162.70113.7A297 S298 I299A297-K301 VanDerWaalsContact O-CB 3.28Å; A297-K301 WeakPolarHBondContact O-CB 3.15Å; S298-K301 PolarHBondContact O-N 3.05Å; I299-K301 PolarHBondContact O-N 3.3Å; I299-K301 VanDerWaalsContact O-N 3.11Å
302Y94.9Very high92.4Very high32 Ų3233.1 Ų33.113%0.12518%0.178CC..Hα-helixtrans-122.2-40.7-169.5-59-57.1000113.9L246 S298 I299 P317 L318L246-Y302 HydrophobicContact CD1-CD2 4.23Å; L246-Y302 HydrophobicContact CG-CD2 4.45Å; S298-Y302 VanDerWaalsContact O-CD2 3.23Å; S298-Y302 WeakPolarHBondContact O-CD2 3.28Å; S298-Y302 PolarHBondContact O-N 3.24Å; I299-Y302 PolarHBondContact O-N 3.36Å; Y302-P317 HydrophobicContact CD1-CB 3.79Å; Y302-P317 HydrophobicContact CD1-CG 3.89Å; Y302-P317 HydrophobicContact CD2-CB 4.07Å; Y302-P317 HydrophobicContact CD2-CG 4.38Å; Y302-P317 HydrophobicContact CE1-CB 4.25Å; Y302-P317 HydrophobicContact CE1-CG 3.83Å; Y302-P317 HydrophobicContact CE2-CB 4.5Å; Y302-P317 HydrophobicContact CE2-CG 4.33Å; Y302-P317 HydrophobicContact CG-CB 3.69Å; Y302-P317 HydrophobicContact CG-CG 4.17Å; Y302-L318 HydrophobicContact CD1-CD2 4.45Å
303I94.2Very high92.3Very high0 Ų036.7 Ų36.70%020%0.195CC..THydrogen-bonded Turntrans-91-40.4-176.5-69.4159.1000110.6L246 V265 I299 Q305 L309 L310 V312L246-I303 HydrophobicContact CD2-CD1 3.91Å; V265-I303 HydrophobicContact CG1-CG2 4.46Å; I299-I303 HydrophobicContact CB-CD1 4.5Å; I299-I303 HydrophobicContact CG1-CD1 4.11Å; I299-I303 HydrophobicContact CG2-CB 4.2Å; I299-I303 HydrophobicContact CG2-CG2 4.34Å; I299-I303 PolarHBondContact O-N 3.34Å; I303-Q305 PolarHBondContact O-N 2.95Å; I303-L309 HydrophobicContact CG2-CB 4.33Å; I303-L310 PolarHBondContact O-N 3.09Å; I303-V312 HydrophobicContact CG1-CG2 3.88Å
304S91.8Very high92.2Very high13 Ų1334 Ų349%0.09118%0.181CC..EExtended strand (participates in β ladder)trans-74.7120.4179.5-165.90000111.8I299 L309I299-S304 PolarHBondContact O-N 2.62Å; S304-L309 WeakPolarHBondContact OG-CD2 3.46Å
305Q84.2Confident91.9Very high101 Ų10136 Ų3647%0.47219%0.189SC..EExtended strand (participates in β ladder)trans-132.573.5173.7-61.4-175.53000108.1I303 L308I303-Q305 PolarHBondContact O-N 2.95Å; Q305-L308 CarbonylContact C-O 3.54Å; Q305-L308 VanDerWaalsContact C-O 3.3Å; Q305-L308 PolarHBondContact N-O 2.84Å; Q305-L308 WeakPolarHBondContact O-CB 3.45Å; Q305-L308 PolarHBondContact O-N 2.9Å
306P71.6Confident91.7Very high77 Ų7742.6 Ų42.650%0.522%0.217SC..THydrogen-bonded Turntrans-52.1131.5-160.3-31.336.3000114.6
307P76.4Confident91.4Very high30 Ų3043 Ų4320%0.19522%0.221CC..THydrogen-bonded Turncis-90.98.69.538.4-38000115M351 I525P307-M351 HydrophobicContact CB-CB 3.97Å; P307-M351 HydrophobicContact CB-CG 4.46Å; P307-M351 HydrophobicContact CG-CB 4.32Å; P307-M351 HydrophobicContact CG-CG 4.4Å; P307-M351 VanDerWaalsContact O-SD 3.41Å; P307-I525 HydrophobicContact CB-CD1 4.02Å
308L88.4Confident91.2Very high30 Ų3047.3 Ų47.316%0.15724%0.235CC..EExtended strand (participates in β ladder)trans-88.7148-176.4-49.3-179.7000111.4Q305 L310 M325 M351 T368 F370Q305-L308 CarbonylContact C-O 3.54Å; Q305-L308 VanDerWaalsContact C-O 3.3Å; Q305-L308 PolarHBondContact N-O 2.84Å; Q305-L308 WeakPolarHBondContact O-CB 3.45Å; Q305-L308 PolarHBondContact O-N 2.9Å; L308-L310 HydrophobicContact CB-CD1 4.4Å; L308-L310 HydrophobicContact CB-CG 4.21Å; L308-L310 HydrophobicContact CD1-CD1 4.2Å; L308-M325 HydrophobicContact CB-SD 4.42Å; L308-M325 HydrophobicContact CD2-CE 3.97Å; L308-M325 HydrophobicContact CD2-SD 4.35Å; L308-M351 HydrophobicContact CD2-SD 3.71Å; L308-T368 HydrophobicContact CD1-CG2 4.01Å; L308-F370 HydrophobicContact CD2-CE1 3.95Å; L308-F370 HydrophobicContact CD2-CZ 4.04Å
309L92.2Very high90.9Very high3 Ų351 Ų512%0.01625%0.254CS..EExtended strand (participates in β ladder)trans-119.1112.5166.8-55.6-177.8000107V265 I303 S304 M325 L329 F332 T348V265-L309 HydrophobicContact CG2-CB 4.03Å; V265-L309 HydrophobicContact CG2-CD1 3.64Å; V265-L309 HydrophobicContact CG2-CG 4.46Å; I303-L309 HydrophobicContact CG2-CB 4.33Å; S304-L309 WeakPolarHBondContact OG-CD2 3.46Å; L309-M325 WeakPolarHBondContact O-CG 3.41Å; L309-L329 HydrophobicContact CB-CD2 4.43Å; L309-L329 HydrophobicContact CD1-CD1 4.46Å; L309-F332 HydrophobicContact CD1-CB 4.42Å; L309-F332 HydrophobicContact CD1-CD1 3.65Å; L309-F332 HydrophobicContact CD1-CE1 4.31Å; L309-F332 HydrophobicContact CD1-CG 4.31Å; L309-T348 HydrophobicContact CD1-CG2 3.99Å; L309-T348 HydrophobicContact CG-CG2 4.23Å
310L91.7Very high90.6Very high15 Ų1554.7 Ų54.78%0.07928%0.278CS..  trans-123.1131.5-171-68.8174.7000112.4I303 L308 M325 T368I303-L310 PolarHBondContact O-N 3.09Å; L308-L310 HydrophobicContact CB-CD1 4.4Å; L308-L310 HydrophobicContact CB-CG 4.21Å; L308-L310 HydrophobicContact CD1-CD1 4.2Å; L310-M325 HydrophobicContact CD2-CE 4.46Å; L310-M325 HydrophobicContact CD2-CG 3.96Å; L310-M325 HydrophobicContact CD2-SD 4.31Å; L310-T368 HydrophobicContact CD1-CG2 3.91Å; L310-T368 HydrophobicContact CD2-CG2 3.8Å; L310-T368 HydrophobicContact CG-CG2 4.48Å
311D93.8Very high90.4Very high7 Ų753.9 Ų53.94%0.03728%0.279CS..  trans-58.9136.2177.9-68.719000111.8S263 G264 P320 A321 R322S263-D311 CarbonylContact O-C 3.48Å; S263-D311 VanDerWaalsContact O-CA 3.27Å; S263-D311 WeakPolarHBondContact O-CA 3.42Å; G264-D311 WeakPolarHBondContact CA-OD1 3.26Å; D311-P320 CarbonylContact O-C 3.58Å; D311-P320 VanDerWaalsContact O-CA 3.28Å; D311-P320 WeakPolarHBondContact O-CA 3.49Å; D311-A321 HydrophobicContact CB-CB 4.4Å; D311-A321 PolarHBondContact O-N 2.98Å; D311-R322 HydrophobicContact CB-CB 4.14Å; D311-R322 HydrophobicContact CB-CG 3.98Å; D311-R322 WeakPolarHBondContact OD2-CD 3.45Å; D311-R322 IonicContact OD2-CZ 4Å; D311-R322 IonicContact OD2-NE 3.17Å; D311-R322 PolarHBondContact OD2-NE 2.67Å; D311-R322 IonicContact OD2-NH1 2.67Å; D311-R322 PolarHBondContact OD2-NH1 2.87Å; D311-R322 IonicContact OD2-NH2 2.9Å
312V95.3Very high90Very high1 Ų149 Ų491%0.00626%0.257CS..EExtended strand (participates in β ladder)trans-127.8159.8178.3-60.30000111.3L246 D262 S263 I303 P317 L319L246-V312 HydrophobicContact CD1-CG2 3.62Å; D262-V312 CarbonylContact C-O 3.5Å; S263-V312 PolarHBondContact N-O 3.04Å; S263-V312 PolarHBondContact O-N 3.06Å; I303-V312 HydrophobicContact CG1-CG2 3.88Å; V312-P317 HydrophobicContact CG2-CB 4.05Å; V312-L319 WeakPolarHBondContact CA-O 3.21Å; V312-L319 WeakPolarHBondContact CB-O 3.29Å
313H95.4Very high89.6Confident77 Ų7752.4 Ų52.436%0.35628%0.281SS..EExtended strand (participates in β ladder)trans-77.6127.1174.3-66.5-59.5000111.7R261 H315 K316 P317 L319 A321R261-H313 WeakPolarHBondContact O-CA 3.37Å; H313-H315 PolarHBondContact O-N 3.05Å; H313-K316 HydrophobicContact CB-CB 4.48Å; H313-K316 CarbonylContact O-C 3.52Å; H313-K316 PolarHBondContact O-N 3.08Å; H313-P317 WeakPolarHBondContact O-CA 3.34Å; H313-P317 VanDerWaalsContact O-N 3.09Å; H313-L319 PolarHBondContact N-O 3.15Å; H313-A321 VanDerWaalsContact CE1-CB 3.46Å; H313-A321 WeakPolarHBondContact CE1-CB 3.35Å
314I94.3Very high89.5Confident0 Ų054.1 Ų54.10%029%0.287CS..THydrogen-bonded Turntrans-52-37.2-17764.9-172.9000113.5Q241 S244 L246 V247 W258 R261 S263Q241-I314 HydrophobicContact CB-CB 4.08Å; Q241-I314 HydrophobicContact CB-CG1 4.31Å; Q241-I314 HydrophobicContact CG-CB 4.46Å; Q241-I314 WeakPolarHBondContact CG-O 3.28Å; S244-I314 PolarHBondContact OG-O 3.43Å; L246-I314 HydrophobicContact CB-CB 4.19Å; L246-I314 HydrophobicContact CB-CG2 3.81Å; V247-I314 WeakPolarHBondContact O-CG2 3.42Å; W258-I314 HydrophobicContact CB-CD1 4.03Å; W258-I314 HydrophobicContact CD2-CD1 4.34Å; W258-I314 HydrophobicContact CG-CD1 3.71Å; R261-I314 HydrophobicContact CB-CD1 4.34Å; R261-I314 HydrophobicContact CB-CG1 4.38Å; R261-I314 HydrophobicContact CG-CD1 4.44Å; R261-I314 PolarHBondContact O-N 3.39Å; S263-I314 VanDerWaalsContact CB-CG2 3.46Å
315H92.6Very high89.5Confident97 Ų9753.5 Ų53.545%0.44928%0.283SS..THydrogen-bonded Turntrans-79.7-23.1-179.4-67.892.6000114Q241 H313Q241-H315 PolarHBondContact NE2-CD2 2.67Å; H313-H315 PolarHBondContact O-N 3.05Å
316K93.4Very high89.9Confident138 Ų13849 Ų4960%0.626%0.262SS*.EExtended strand (participates in β ladder)trans-140.566.6-176.5-66.4-177.5-178.5174.20108.8H313 L318 L319H313-K316 HydrophobicContact CB-CB 4.48Å; H313-K316 CarbonylContact O-C 3.52Å; H313-K316 PolarHBondContact O-N 3.08Å; K316-L318 PolarHBondContact O-N 2.78Å; K316-L319 HydrophobicContact CB-CD1 4.01Å; K316-L319 HydrophobicContact CB-CG 4.28Å; K316-L319 HydrophobicContact CD-CD1 3.74Å; K316-L319 PolarHBondContact O-N 2.97Å
317P91.7Very high91Very high20 Ų2045.3 Ų45.313%0.1324%0.238CC..EExtended strand (participates in β ladder)trans-73.714.7-16734.4-41.5000114.5L246 Y302 V312 H313L246-P317 HydrophobicContact CD1-CB 3.96Å; Y302-P317 HydrophobicContact CD1-CB 3.79Å; Y302-P317 HydrophobicContact CD1-CG 3.89Å; Y302-P317 HydrophobicContact CD2-CB 4.07Å; Y302-P317 HydrophobicContact CD2-CG 4.38Å; Y302-P317 HydrophobicContact CE1-CB 4.25Å; Y302-P317 HydrophobicContact CE1-CG 3.83Å; Y302-P317 HydrophobicContact CE2-CB 4.5Å; Y302-P317 HydrophobicContact CE2-CG 4.33Å; Y302-P317 HydrophobicContact CG-CB 3.69Å; Y302-P317 HydrophobicContact CG-CG 4.17Å; V312-P317 HydrophobicContact CG2-CB 4.05Å; H313-P317 WeakPolarHBondContact O-CA 3.34Å; H313-P317 VanDerWaalsContact O-N 3.09Å
318L90.4Very high91.9Very high151 Ų15145.4 Ų45.479%0.79124%0.237SC*.EExtended strand (participates in β ladder)trans-106.40.3170.1-58.4178.8000111.8Y302 K316Y302-L318 HydrophobicContact CD1-CD2 4.45Å; K316-L318 PolarHBondContact O-N 2.78Å
319L91.1Very high92.2Very high89 Ų8944.1 Ų44.147%0.46623%0.23SC..EExtended strand (participates in β ladder)trans-109.9124174.1-61.3-179.5000108.7V312 H313 K316V312-L319 WeakPolarHBondContact CA-O 3.21Å; V312-L319 WeakPolarHBondContact CB-O 3.29Å; H313-L319 PolarHBondContact N-O 3.15Å; K316-L319 HydrophobicContact CB-CD1 4.01Å; K316-L319 HydrophobicContact CB-CG 4.28Å; K316-L319 HydrophobicContact CD-CD1 3.74Å; K316-L319 PolarHBondContact O-N 2.97Å
320P89.6Confident92.5Very high78 Ų7844 Ų4451%0.50623%0.23SC..EExtended strand (participates in β ladder)trans-65.4138.3172.229.2-33.9000109.7D311D311-P320 CarbonylContact O-C 3.58Å; D311-P320 VanDerWaalsContact O-CA 3.28Å; D311-P320 WeakPolarHBondContact O-CA 3.49Å
321A90.2Very high92.8Very high33 Ų3343.7 Ų43.727%0.27323%0.228SC..SBendtrans-93.2-27.3175.200000112.2D262 D311 H313D262-A321 HydrophobicContact CB-CB 3.6Å; D311-A321 HydrophobicContact CB-CB 4.4Å; D311-A321 PolarHBondContact O-N 2.98Å; H313-A321 VanDerWaalsContact CE1-CB 3.46Å; H313-A321 WeakPolarHBondContact CE1-CB 3.35Å
322R86.8Confident92.9Very high37 Ų3743.3 Ų43.314%0.1423%0.226CC..  trans-128.1160.7175.2-54.5-173.9-170.7162.88.5110.4D262 D311D262-R322 IonicContact OD2-CZ 2.62Å; D262-R322 IonicContact OD2-NE 3.16Å; D262-R322 PolarHBondContact OD2-NE 3.37Å; D262-R322 IonicContact OD2-NH2 2.68Å; D262-R322 PolarHBondContact OD2-NH2 2.85Å; D311-R322 HydrophobicContact CB-CB 4.14Å; D311-R322 HydrophobicContact CB-CG 3.98Å; D311-R322 WeakPolarHBondContact OD2-CD 3.45Å; D311-R322 IonicContact OD2-CZ 4Å; D311-R322 IonicContact OD2-NE 3.17Å; D311-R322 PolarHBondContact OD2-NE 2.67Å; D311-R322 IonicContact OD2-NH1 2.67Å; D311-R322 PolarHBondContact OD2-NH1 2.87Å; D311-R322 IonicContact OD2-NH2 2.9Å
323T87.1Confident93Very high103 Ų10343.3 Ų43.363%0.63223%0.225SC*.SBendtrans-113.111.1178.254.50000113
324W90.8Very high93.1Very high36 Ų3639.6 Ų39.614%0.13621%0.208CC..EExtended strand (participates in β ladder)trans-141.7165.4-177.553.5-99.8000109.6D326 A365 F366 H373 W374W324-D326 HydrophobicContact CZ3-CB 4.2Å; W324-A365 HydrophobicContact CD2-CB 4.39Å; W324-A365 HydrophobicContact CE3-CB 3.79Å; W324-A365 HydrophobicContact CZ3-CB 4.21Å; W324-F366 CarbonylContact C-O 3.49Å; W324-F366 VanDerWaalsContact CA-O 3.23Å; W324-F366 WeakPolarHBondContact CA-O 3.15Å; W324-F366 WeakPolarHBondContact CB-O 3.39Å; W324-H373 HydrophobicContact CB-CB 4.32Å; W324-H373 AromaticContact CD1-CD2 3.6Å; W324-H373 AromaticContact CD1-CE1 3.95Å; W324-H373 AromaticContact CD1-NE2 3.47Å; W324-H373 AromaticContact CD2-CD2 3.94Å; W324-H373 AromaticContact CG-CD2 3.67Å; W324-H373 AromaticContact NE1-CD2 3.8Å; W324-H373 AromaticContact NE1-NE2 3.46Å; W324-H373 PolarHBondContact NE1-NE2 3.23Å; W324-W374 AromaticContact CH2-CH2 3.35Å; W324-W374 HydrophobicContact CH2-CH2 3.35Å; W324-W374 HydrophobicContact CH2-CZ2 4.15Å; W324-W374 AromaticContact CH2-CZ3 3.63Å; W324-W374 HydrophobicContact CH2-CZ3 3.63Å; W324-W374 AromaticContact CZ2-CH2 3.54Å; W324-W374 HydrophobicContact CZ2-CH2 3.54Å; W324-W374 AromaticContact CZ2-CZ2 3.89Å; W324-W374 HydrophobicContact CZ2-CZ2 3.89Å; W324-W374 HydrophobicContact CZ2-CZ3 4.22Å; W324-W374 HydrophobicContact CZ3-CH2 4.12Å; W324-W374 AromaticContact CZ3-CZ3 3.95Å; W324-W374 HydrophobicContact CZ3-CZ3 3.95Å
325M92.8Very high93.2Very high1 Ų139.7 Ų39.71%0.00521%0.209CC..EExtended strand (participates in β ladder)trans-119136.5176.8-74.9162.2-71.700108.3L308 L309 L310 L329 M351 A365 F366L308-M325 HydrophobicContact CB-SD 4.42Å; L308-M325 HydrophobicContact CD2-CE 3.97Å; L308-M325 HydrophobicContact CD2-SD 4.35Å; L309-M325 WeakPolarHBondContact O-CG 3.41Å; L310-M325 HydrophobicContact CD2-CE 4.46Å; L310-M325 HydrophobicContact CD2-CG 3.96Å; L310-M325 HydrophobicContact CD2-SD 4.31Å; M325-L329 HydrophobicContact CB-CD2 3.7Å; M325-L329 HydrophobicContact CG-CD2 3.8Å; M325-L329 HydrophobicContact SD-CD2 4.48Å; M325-M351 HydrophobicContact SD-CE 4.48Å; M325-M351 HydrophobicContact SD-SD 4.46Å; M325-A365 CarbonylContact O-C 3.6Å; M325-A365 WeakPolarHBondContact O-CA 3.43Å; M325-A365 WeakPolarHBondContact O-CB 3.5Å; M325-F366 HydrophobicContact CB-CD1 4.49Å; M325-F366 HydrophobicContact CB-CE1 4.05Å; M325-F366 HydrophobicContact CB-CE2 4.18Å; M325-F366 HydrophobicContact CB-CZ 3.88Å; M325-F366 HydrophobicContact CE-CD2 3.79Å; M325-F366 HydrophobicContact CE-CE2 3.4Å; M325-F366 HydrophobicContact CE-CZ 4.16Å; M325-F366 PolarHBondContact N-O 3.47Å; M325-F366 PolarHBondContact O-N 3.31Å; M325-F366 HydrophobicContact SD-CE2 3.97Å; M325-F366 HydrophobicContact SD-CZ 4.18Å
326D93.4Very high93.3Very high5 Ų535.1 Ų35.13%0.02719%0.188CC..EExtended strand (participates in β ladder)trans-73.6170.2165.952.179.6000111.9G266 A267 W324 L328 L329 E364G266-D326 VanDerWaalsContact CA-OD1 3.29Å; G266-D326 WeakPolarHBondContact CA-OD1 3.19Å; A267-D326 PolarHBondContact N-OD1 3.39Å; A267-D326 PolarHBondContact N-OD2 2.69Å; W324-D326 HydrophobicContact CZ3-CB 4.2Å; D326-L328 HydrophobicContact CB-CD1 4.27Å; D326-L328 PolarHBondContact OD1-N 2.89Å; D326-L329 WeakPolarHBondContact O-CG 3.37Å; D326-L329 PolarHBondContact OD1-N 3.02Å; D326-L329 VanDerWaalsContact OD1-N 3.12Å; D326-E364 CarbonylContact C-O 3.54Å; D326-E364 WeakPolarHBondContact CA-O 3.47Å
327S94.5Very high93.4Very high0 Ų029.3 Ų29.30%016%0.164CC..SBendtrans-76.3-27.4173.155.20000113.6L329 A330 E364S327-L329 PolarHBondContact O-N 3.44Å; S327-A330 WeakPolarHBondContact O-CB 3.4Å; S327-A330 PolarHBondContact O-N 3.03Å; S327-E364 PolarHBondContact N-O 3.46Å; S327-E364 PolarHBondContact OG-OE2 3.06Å
328L94.4Very high93.5Very high33 Ų3331.3 Ų31.317%0.17317%0.173CC..G310 helixtrans-65.4-29.9-170.6-67.284.6000111.6A267 D326 A330 F331A267-L328 HydrophobicContact CB-CD1 4.47Å; D326-L328 HydrophobicContact CB-CD1 4.27Å; D326-L328 PolarHBondContact OD1-N 2.89Å; L328-A330 PolarHBondContact O-N 3.37Å; L328-F331 WeakPolarHBondContact O-CD1 3.32Å; L328-F331 PolarHBondContact O-N 2.88Å
329L95.6Very high93.6Very high3 Ų327.4 Ų27.42%0.01615%0.15CC..G310 helixtrans-54.1-12.7171.476.775000114.9V265 L309 M325 D326 S327 F331 F332 L352V265-L329 HydrophobicContact CG2-CB 3.88Å; L309-L329 HydrophobicContact CB-CD2 4.43Å; L309-L329 HydrophobicContact CD1-CD1 4.46Å; M325-L329 HydrophobicContact CB-CD2 3.7Å; M325-L329 HydrophobicContact CG-CD2 3.8Å; M325-L329 HydrophobicContact SD-CD2 4.48Å; D326-L329 WeakPolarHBondContact O-CG 3.37Å; D326-L329 PolarHBondContact OD1-N 3.02Å; D326-L329 VanDerWaalsContact OD1-N 3.12Å; S327-L329 PolarHBondContact O-N 3.44Å; L329-F331 PolarHBondContact O-N 2.75Å; L329-F331 VanDerWaalsContact O-N 3.16Å; L329-F332 VanDerWaalsContact O-CB 3.28Å; L329-F332 WeakPolarHBondContact O-CB 3.11Å; L329-F332 PolarHBondContact O-N 3.35Å; L329-L352 HydrophobicContact CD1-CD1 4.37Å; L329-L352 HydrophobicContact CD1-CD2 4.06Å
330A97.4Very high93.5Very high0 Ų024 Ų240%014%0.135CC..G310 helixtrans-63.3-11.2176.300000114.5S327 L328 F332 P333 L352 L362 E382 F383 S386S327-A330 WeakPolarHBondContact O-CB 3.4Å; S327-A330 PolarHBondContact O-N 3.03Å; L328-A330 PolarHBondContact O-N 3.37Å; A330-F332 VanDerWaalsContact C-N 3.35Å; A330-P333 WeakPolarHBondContact O-CD 3.29Å; A330-L352 HydrophobicContact CB-CD1 3.76Å; A330-L352 HydrophobicContact CB-CD2 4.38Å; A330-L362 HydrophobicContact CB-CD2 3.83Å; A330-E382 CarbonylContact C-O 3.54Å; A330-E382 HydrophobicContact CB-CB 4.1Å; A330-E382 VanDerWaalsContact O-O 3.06Å; A330-F383 HydrophobicContact CB-CB 4.04Å; A330-S386 VanDerWaalsContact O-CB 3.26Å; A330-S386 WeakPolarHBondContact O-CB 3.32Å; A330-S386 PolarHBondContact O-OG 3.05Å
331F97.8Very high93.5Very high8 Ų822.7 Ų22.74%0.03513%0.125CC..G310 helixtrans-71.5-28.716992.2-67.6000112.4V265 D270 E274 L328 L329 G334 L335 E382 E385 S386V265-F331 WeakPolarHBondContact O-CE1 3.4Å; D270-F331 HydrophobicContact CB-CD1 4.42Å; D270-F331 HydrophobicContact CB-CE1 3.82Å; D270-F331 HydrophobicContact CB-CZ 4.03Å; D270-F331 VanDerWaalsContact O-CZ 3.31Å; D270-F331 WeakPolarHBondContact O-CZ 3.38Å; E274-F331 HydrophobicContact CB-CE2 3.92Å; E274-F331 HydrophobicContact CG-CD2 4.27Å; E274-F331 HydrophobicContact CG-CE2 4.09Å; L328-F331 WeakPolarHBondContact O-CD1 3.32Å; L328-F331 PolarHBondContact O-N 2.88Å; L329-F331 PolarHBondContact O-N 2.75Å; L329-F331 VanDerWaalsContact O-N 3.16Å; F331-G334 WeakPolarHBondContact O-CA 3.33Å; F331-G334 PolarHBondContact O-N 2.94Å; F331-L335 HydrophobicContact CE2-CB 4.32Å; F331-L335 HydrophobicContact CE2-CD2 3.86Å; F331-L335 HydrophobicContact CZ-CD2 4.26Å; F331-L335 PolarHBondContact O-N 2.73Å; F331-E382 HydrophobicContact CB-CB 3.99Å; F331-E382 HydrophobicContact CB-CG 4.36Å; F331-E385 WeakPolarHBondContact CA-OE2 3.49Å; F331-E385 VanDerWaalsContact CB-OE2 3.31Å; F331-E385 WeakPolarHBondContact CB-OE2 3.23Å; F331-S386 PolarHBondContact O-OG 2.97Å
332F97.3Very high93.5Very high0 Ų021.6 Ų21.60%011%0.114CC..Hα-helixtrans-63.2-35.5-167-166-105.4000114.2V265 Y296 I299 M300 L309 L329 A330 G334 L335 Q336V265-F332 HydrophobicContact CB-CD2 3.98Å; V265-F332 HydrophobicContact CB-CE2 4.35Å; V265-F332 HydrophobicContact CB-CG 4.2Å; V265-F332 HydrophobicContact CG1-CD1 4.41Å; V265-F332 HydrophobicContact CG1-CD2 3.78Å; V265-F332 HydrophobicContact CG1-CE1 4.28Å; V265-F332 HydrophobicContact CG1-CE2 3.64Å; V265-F332 HydrophobicContact CG1-CG 4.18Å; V265-F332 HydrophobicContact CG1-CZ 3.91Å; V265-F332 HydrophobicContact CG2-CB 4.47Å; V265-F332 HydrophobicContact CG2-CG 4.33Å; Y296-F332 HydrophobicContact CD2-CZ 4.06Å; Y296-F332 HydrophobicContact CE2-CE1 4.26Å; Y296-F332 AromaticContact CE2-CZ 3.75Å; Y296-F332 HydrophobicContact CE2-CZ 3.75Å; I299-F332 HydrophobicContact CD1-CE2 4.32Å; I299-F332 HydrophobicContact CD1-CZ 4.38Å; I299-F332 HydrophobicContact CG2-CE1 4.2Å; I299-F332 HydrophobicContact CG2-CE2 4.48Å; I299-F332 HydrophobicContact CG2-CZ 3.73Å; M300-F332 HydrophobicContact SD-CE1 4.49Å; L309-F332 HydrophobicContact CD1-CB 4.42Å; L309-F332 HydrophobicContact CD1-CD1 3.65Å; L309-F332 HydrophobicContact CD1-CE1 4.31Å; L309-F332 HydrophobicContact CD1-CG 4.31Å; L329-F332 VanDerWaalsContact O-CB 3.28Å; L329-F332 WeakPolarHBondContact O-CB 3.11Å; L329-F332 PolarHBondContact O-N 3.35Å; A330-F332 VanDerWaalsContact C-N 3.35Å; F332-G334 VanDerWaalsContact C-N 3.29Å; F332-G334 PolarHBondContact O-N 2.92Å; F332-L335 HydrophobicContact CD2-CD2 4.13Å; F332-L335 HydrophobicContact CE2-CD2 4.17Å; F332-L335 PolarHBondContact O-N 3.34Å; F332-Q336 HydrophobicContact CD1-CG 3.95Å; F332-Q336 HydrophobicContact CE1-CG 3.77Å; F332-Q336 HydrophobicContact CZ-CG 4.31Å; F332-Q336 WeakPolarHBondContact O-CB 3.45Å; F332-Q336 VanDerWaalsContact O-CG 3.31Å; F332-Q336 WeakPolarHBondContact O-CG 3.33Å; F332-Q336 PolarHBondContact O-N 2.79Å
333P96.8Very high93.6Very high0 Ų026.4 Ų26.40%013%0.132CC..Hα-helixtrans-59.2-34.8169.8-24.534.9000113.8A330 Q336 V337 A345 T348 H349 L352 S386 L390A330-P333 WeakPolarHBondContact O-CD 3.29Å; P333-Q336 WeakPolarHBondContact O-CB 3.3Å; P333-Q336 PolarHBondContact O-N 3.37Å; P333-V337 WeakPolarHBondContact O-CG2 3.36Å; P333-V337 PolarHBondContact O-N 3.04Å; P333-A345 HydrophobicContact CB-CB 3.99Å; P333-A345 WeakPolarHBondContact O-CB 3.15Å; P333-T348 HydrophobicContact CG-CG2 4.01Å; P333-H349 HydrophobicContact CB-CB 4.33Å; P333-H349 HydrophobicContact CG-CB 4.48Å; P333-L352 HydrophobicContact CG-CD1 4.3Å; P333-S386 WeakPolarHBondContact CD-OG 3.27Å; P333-L390 HydrophobicContact CB-CD1 4.36Å
334G96.6Very high93.7Very high0 Ų022.2 Ų22.20%011%0.107CC..Hα-helixtrans-65.1-46.2172.300000111.7F331 F332 Q336 V337 L338 S386F331-G334 WeakPolarHBondContact O-CA 3.33Å; F331-G334 PolarHBondContact O-N 2.94Å; F332-G334 VanDerWaalsContact C-N 3.29Å; F332-G334 PolarHBondContact O-N 2.92Å; G334-Q336 VanDerWaalsContact C-N 3.3Å; G334-Q336 PolarHBondContact O-N 2.96Å; G334-V337 WeakPolarHBondContact O-CA 3.27Å; G334-V337 WeakPolarHBondContact O-CB 3.28Å; G334-V337 PolarHBondContact O-N 3.48Å; G334-L338 PolarHBondContact O-N 3.37Å; G334-S386 PolarHBondContact N-OG 3.07Å
335L96.8Very high93.8Very high2 Ų220.5 Ų20.51%0.0110%0.1CC..Hα-helixtrans-61.4-36.8173.5-171.464.1000112.6E274 L277 F292 F331 F332 L338 K339E274-L335 HydrophobicContact CB-CD1 4.48Å; E274-L335 HydrophobicContact CB-CD2 4.49Å; E274-L335 HydrophobicContact CG-CD1 4.21Å; L277-L335 HydrophobicContact CB-CD1 4.03Å; L277-L335 HydrophobicContact CD2-CD1 3.81Å; F292-L335 HydrophobicContact CE2-CD1 4.42Å; F292-L335 HydrophobicContact CE2-CD2 3.94Å; F292-L335 HydrophobicContact CE2-CG 4.17Å; F292-L335 HydrophobicContact CZ-CD1 4.46Å; F292-L335 HydrophobicContact CZ-CD2 4.44Å; F292-L335 HydrophobicContact CZ-CG 4.19Å; F331-L335 HydrophobicContact CE2-CB 4.32Å; F331-L335 HydrophobicContact CE2-CD2 3.86Å; F331-L335 HydrophobicContact CZ-CD2 4.26Å; F331-L335 PolarHBondContact O-N 2.73Å; F332-L335 HydrophobicContact CD2-CD2 4.13Å; F332-L335 HydrophobicContact CE2-CD2 4.17Å; F332-L335 PolarHBondContact O-N 3.34Å; L335-L338 PolarHBondContact O-N 3.09Å; L335-K339 PolarHBondContact O-N 3.4Å
336Q95.3Very high93.8Very high0 Ų020.5 Ų20.50%010%0.1CC..Hα-helixtrans-65.3-36.9172.2-75-177.2-45.400112.4Y296 M300 F332 P333 G334 K339 G340 D341 A345Y296-Q336 HydrophobicContact CE2-CG 3.86Å; Y296-Q336 WeakPolarHBondContact OH-CG 3.18Å; Y296-Q336 PolarHBondContact OH-NE2 3.09Å; M300-Q336 PolarHBondContact SD-NE2 3.08Å; F332-Q336 HydrophobicContact CD1-CG 3.95Å; F332-Q336 HydrophobicContact CE1-CG 3.77Å; F332-Q336 HydrophobicContact CZ-CG 4.31Å; F332-Q336 WeakPolarHBondContact O-CB 3.45Å; F332-Q336 VanDerWaalsContact O-CG 3.31Å; F332-Q336 WeakPolarHBondContact O-CG 3.33Å; F332-Q336 PolarHBondContact O-N 2.79Å; P333-Q336 WeakPolarHBondContact O-CB 3.3Å; P333-Q336 PolarHBondContact O-N 3.37Å; G334-Q336 VanDerWaalsContact C-N 3.3Å; G334-Q336 PolarHBondContact O-N 2.96Å; Q336-K339 PolarHBondContact O-N 3.43Å; Q336-G340 PolarHBondContact O-N 2.93Å; Q336-D341 PolarHBondContact O-N 3.32Å; Q336-A345 HydrophobicContact CB-CB 3.83Å
337V94.9Very high93.7Very high16 Ų1621.4 Ų21.410%0.09710%0.104CC..Hα-helixtrans-65.6-44.4172.31690000111.6P333 G334 K339 G340 I342 A345 F389 L390 A393P333-V337 WeakPolarHBondContact O-CG2 3.36Å; P333-V337 PolarHBondContact O-N 3.04Å; G334-V337 WeakPolarHBondContact O-CA 3.27Å; G334-V337 WeakPolarHBondContact O-CB 3.28Å; G334-V337 PolarHBondContact O-N 3.48Å; V337-K339 PolarHBondContact O-N 3.48Å; V337-G340 WeakPolarHBondContact O-CA 3.17Å; V337-G340 PolarHBondContact O-N 3.38Å; V337-I342 HydrophobicContact CB-CD1 4.29Å; V337-I342 HydrophobicContact CG1-CD1 4.18Å; V337-I342 HydrophobicContact CG2-CD1 4.13Å; V337-A345 HydrophobicContact CG2-CB 4.13Å; V337-F389 HydrophobicContact CB-CB 4.14Å; V337-F389 HydrophobicContact CG1-CB 4Å; V337-L390 HydrophobicContact CG2-CD2 3.5Å; V337-L390 VanDerWaalsContact CG2-CD2 3.5Å; V337-L390 HydrophobicContact CG2-CG 3.8Å; V337-A393 HydrophobicContact CG1-CB 3.58Å
338L93.3Very high93.7Very high63 Ų6321.5 Ų21.533%0.3311%0.105SC..Hα-helixtrans-60.5-34.7174.5-70.1174000112.2L277 G334 L335 G340 F389L277-L338 HydrophobicContact CD2-CB 3.72Å; G334-L338 PolarHBondContact O-N 3.37Å; L335-L338 PolarHBondContact O-N 3.09Å; L338-G340 VanDerWaalsContact C-N 3.29Å; L338-G340 PolarHBondContact O-N 2.73Å; L338-F389 HydrophobicContact CD1-CZ 4.35Å; L338-F389 HydrophobicContact CD2-CD1 4.15Å; L338-F389 HydrophobicContact CD2-CE1 3.79Å; L338-F389 HydrophobicContact CD2-CZ 4.37Å; L338-F389 HydrophobicContact CG-CD1 4.45Å; L338-F389 HydrophobicContact CG-CE1 4.29Å
339K92.3Very high93.7Very high69 Ų6920 Ų2030%0.310%0.097SC..Hα-helixtrans-70.3-22.1170.5-179170.4173.752.70113.6L277 F292 N293 Y296 L335 Q336 V337L277-K339 HydrophobicContact CD2-CB 4.37Å; F292-K339 HydrophobicContact CE1-CB 4.02Å; F292-K339 HydrophobicContact CE1-CD 3.68Å; F292-K339 HydrophobicContact CE1-CG 4.01Å; F292-K339 HydrophobicContact CZ-CB 4.25Å; F292-K339 HydrophobicContact CZ-CD 4.08Å; N293-K339 PolarHBondContact OD1-NZ 3.21Å; Y296-K339 HydrophobicContact CD1-CD 3.54Å; Y296-K339 HydrophobicContact CD2-CD 3.84Å; Y296-K339 HydrophobicContact CE1-CD 3.63Å; Y296-K339 HydrophobicContact CE2-CD 3.97Å; Y296-K339 HydrophobicContact CG-CD 3.64Å; L335-K339 PolarHBondContact O-N 3.4Å; Q336-K339 PolarHBondContact O-N 3.43Å; V337-K339 PolarHBondContact O-N 3.48Å
340G90.1Very high93.6Very high16 Ų1619.9 Ų19.917%0.16510%0.096CC..THydrogen-bonded Turntrans87.66.5-172.600000115.3Q336 V337 L338 I342Q336-G340 PolarHBondContact O-N 2.93Å; V337-G340 WeakPolarHBondContact O-CA 3.17Å; V337-G340 PolarHBondContact O-N 3.38Å; L338-G340 VanDerWaalsContact C-N 3.29Å; L338-G340 PolarHBondContact O-N 2.73Å; G340-I342 VanDerWaalsContact C-N 3.31Å; G340-I342 PolarHBondContact O-N 2.87Å; G340-I342 VanDerWaalsContact O-N 3.13Å
341D90.4Very high93.4Very high52 Ų5219.9 Ų19.928%0.27810%0.096SC..  trans-88.866.1178-166.26.8000111Y296 Q336 R343 P344Y296-D341 WeakPolarHBondContact CE1-OD2 3.33Å; Y296-D341 PolarHBondContact OH-OD2 2.75Å; Q336-D341 PolarHBondContact O-N 3.32Å; D341-R343 VanDerWaalsContact C-N 3.28Å; D341-R343 PolarHBondContact O-N 3.36Å; D341-P344 WeakPolarHBondContact O-CD 3.47Å; D341-P344 WeakPolarHBondContact OD1-CD 3.44Å
342I89.8Confident93.3Very high10 Ų1019.5 Ų19.55%0.05110%0.095CC..Hα-helixtrans-68-24.6-166.7-39.2-57.6000112.9V337 G340 A345 I346 L390 A393 T394 L511 F512V337-I342 HydrophobicContact CB-CD1 4.29Å; V337-I342 HydrophobicContact CG1-CD1 4.18Å; V337-I342 HydrophobicContact CG2-CD1 4.13Å; G340-I342 VanDerWaalsContact C-N 3.31Å; G340-I342 PolarHBondContact O-N 2.87Å; G340-I342 VanDerWaalsContact O-N 3.13Å; I342-A345 WeakPolarHBondContact O-CB 3.21Å; I342-A345 PolarHBondContact O-N 3.38Å; I342-I346 HydrophobicContact CG2-CD1 4.03Å; I342-I346 HydrophobicContact CG2-CG1 4.28Å; I342-I346 WeakPolarHBondContact O-CD1 3.46Å; I342-I346 VanDerWaalsContact O-CG1 3.26Å; I342-I346 WeakPolarHBondContact O-CG1 3.35Å; I342-I346 PolarHBondContact O-N 3.42Å; I342-L390 HydrophobicContact CG2-CD2 4.17Å; I342-A393 HydrophobicContact CD1-CB 4.45Å; I342-T394 HydrophobicContact CG2-CG2 3.91Å; I342-L511 HydrophobicContact CG1-CD1 4.33Å; I342-F512 HydrophobicContact CB-CE2 4.3Å; I342-F512 HydrophobicContact CB-CZ 3.84Å; I342-F512 HydrophobicContact CG1-CE2 4.25Å; I342-F512 HydrophobicContact CG1-CZ 4.28Å; I342-F512 HydrophobicContact CG2-CE2 4.11Å; I342-F512 HydrophobicContact CG2-CZ 3.66Å
343R87.7Confident93.2Very high137 Ų13719.8 Ų19.852%0.51710%0.096SC..Hα-helixtrans-69.9-54.6-173.3166172.3179.3-148.7-13.2112.7D341 A345 I346 E347 L521D341-R343 VanDerWaalsContact C-N 3.28Å; D341-R343 PolarHBondContact O-N 3.36Å; R343-A345 PolarHBondContact O-N 2.85Å; R343-I346 PolarHBondContact O-N 2.89Å; R343-I346 VanDerWaalsContact O-N 3.17Å; R343-E347 IonicContact CZ-OE1 3.78Å; R343-E347 IonicContact NE-OE1 3.5Å; R343-E347 PolarHBondContact NE-OE1 2.85Å; R343-E347 IonicContact NH2-OE1 3.47Å; R343-E347 PolarHBondContact NH2-OE1 3.1Å; R343-E347 PolarHBondContact O-N 2.84Å; R343-E347 VanDerWaalsContact O-N 3.1Å; R343-L521 HydrophobicContact CB-CD1 4.37Å; R343-L521 HydrophobicContact CG-CD1 3.91Å; R343-L521 HydrophobicContact CG-CD2 4.29Å
344P90.8Very high93Very high16 Ų1620.6 Ų20.610%0.10410%0.1CC..Hα-helixtrans-59.6-31.1174.2-2637000112.9M300 D341 E347 T348M300-P344 HydrophobicContact CE-CB 3.81Å; M300-P344 HydrophobicContact CE-CG 3.75Å; D341-P344 WeakPolarHBondContact O-CD 3.47Å; D341-P344 WeakPolarHBondContact OD1-CD 3.44Å; P344-E347 PolarHBondContact O-N 2.91Å; P344-T348 WeakPolarHBondContact O-CB 3.31Å; P344-T348 PolarHBondContact O-N 2.93Å; P344-T348 PolarHBondContact O-OG1 3.2Å
345A92.9Very high92.9Very high0 Ų020.6 Ų20.60%010%0.1CC..Hα-helixtrans-62-46.3173.800000111.9P333 Q336 V337 I342 R343 T348 H349 L390P333-A345 HydrophobicContact CB-CB 3.99Å; P333-A345 WeakPolarHBondContact O-CB 3.15Å; Q336-A345 HydrophobicContact CB-CB 3.83Å; V337-A345 HydrophobicContact CG2-CB 4.13Å; I342-A345 WeakPolarHBondContact O-CB 3.21Å; I342-A345 PolarHBondContact O-N 3.38Å; R343-A345 PolarHBondContact O-N 2.85Å; A345-T348 PolarHBondContact O-N 2.87Å; A345-H349 WeakPolarHBondContact O-CB 3.47Å; A345-H349 PolarHBondContact O-N 3.28Å; A345-L390 HydrophobicContact CB-CD2 3.94Å
346I92.5Very high92.7Very high0 Ų020.9 Ų20.90%010%0.101CC..Hα-helixtrans-60.8-44.7174.3-64.8160.3000111.2I342 R343 E350 L390 F512 P518 L521 R522I342-I346 HydrophobicContact CG2-CD1 4.03Å; I342-I346 HydrophobicContact CG2-CG1 4.28Å; I342-I346 WeakPolarHBondContact O-CD1 3.46Å; I342-I346 VanDerWaalsContact O-CG1 3.26Å; I342-I346 WeakPolarHBondContact O-CG1 3.35Å; I342-I346 PolarHBondContact O-N 3.42Å; R343-I346 PolarHBondContact O-N 2.89Å; R343-I346 VanDerWaalsContact O-N 3.17Å; I346-E350 WeakPolarHBondContact O-CB 3.48Å; I346-E350 PolarHBondContact O-N 3.18Å; I346-E350 VanDerWaalsContact O-N 3.1Å; I346-L390 HydrophobicContact CG1-CD2 4.14Å; I346-F512 HydrophobicContact CD1-CE1 4.21Å; I346-F512 HydrophobicContact CD1-CZ 4.27Å; I346-P518 HydrophobicContact CD1-CB 4.25Å; I346-L521 HydrophobicContact CB-CD1 4.11Å; I346-L521 HydrophobicContact CD1-CD1 3.9Å; I346-L521 HydrophobicContact CG2-CB 3.95Å; I346-L521 HydrophobicContact CG2-CD1 4Å; I346-R522 HydrophobicContact CG2-CG 4.05Å
347E91.3Very high92.6Very high24 Ų2424.7 Ų24.711%0.11212%0.118CC..Hα-helixtrans-65.2-41.6-178.6-68.9176.4-174.200111.8R343 P344 M351 L521 I525R343-E347 IonicContact CZ-OE1 3.78Å; R343-E347 IonicContact NE-OE1 3.5Å; R343-E347 PolarHBondContact NE-OE1 2.85Å; R343-E347 IonicContact NH2-OE1 3.47Å; R343-E347 PolarHBondContact NH2-OE1 3.1Å; R343-E347 PolarHBondContact O-N 2.84Å; R343-E347 VanDerWaalsContact O-N 3.1Å; P344-E347 PolarHBondContact O-N 2.91Å; E347-M351 PolarHBondContact O-N 3.37Å; E347-L521 HydrophobicContact CG-CB 4.39Å; E347-I525 HydrophobicContact CB-CD1 4.02Å; E347-I525 HydrophobicContact CG-CD1 4.33Å; E347-I525 VanDerWaalsContact O-CD1 3.29Å; E347-I525 WeakPolarHBondContact O-CD1 3.14Å
348T93.1Very high92.4Very high2 Ų227.3 Ų27.31%0.01213%0.128CC..Hα-helixtrans-75.4-43.5180-50.10000112L309 P333 P344 A345 E350 M351 L352L309-T348 HydrophobicContact CD1-CG2 3.99Å; L309-T348 HydrophobicContact CG-CG2 4.23Å; P333-T348 HydrophobicContact CG-CG2 4.01Å; P344-T348 WeakPolarHBondContact O-CB 3.31Å; P344-T348 PolarHBondContact O-N 2.93Å; P344-T348 PolarHBondContact O-OG1 3.2Å; A345-T348 PolarHBondContact O-N 2.87Å; T348-E350 PolarHBondContact O-N 2.85Å; T348-M351 WeakPolarHBondContact O-CB 3.48Å; T348-M351 PolarHBondContact O-N 3.22Å; T348-L352 HydrophobicContact CG2-CD1 4.41Å; T348-L352 WeakPolarHBondContact O-CG 3.17Å; T348-L352 PolarHBondContact O-N 2.81Å; T348-L352 VanDerWaalsContact O-N 3.08Å
349H95.6Very high92.3Very high1 Ų125.5 Ų25.51%0.00512%0.118CC..Hα-helixtrans-62.7-40.7178.1-178.7-86.7000112.4P333 A345 M351 L352 Y353 F383 T387 L390 Y399P333-H349 HydrophobicContact CB-CB 4.33Å; P333-H349 HydrophobicContact CG-CB 4.48Å; A345-H349 WeakPolarHBondContact O-CB 3.47Å; A345-H349 PolarHBondContact O-N 3.28Å; H349-M351 VanDerWaalsContact C-N 3.32Å; H349-M351 PolarHBondContact O-N 3.02Å; H349-L352 PolarHBondContact O-N 3.28Å; H349-Y353 WeakPolarHBondContact O-CB 3.46Å; H349-Y353 PolarHBondContact O-N 2.85Å; H349-F383 AromaticContact CD2-CE2 3.64Å; H349-F383 AromaticContact CE1-CE2 3.82Å; H349-F383 AromaticContact CE1-CZ 3.92Å; H349-F383 AromaticContact NE2-CD2 4Å; H349-F383 AromaticContact NE2-CE2 3.33Å; H349-F383 VanDerWaalsContact NE2-CE2 3.33Å; H349-F383 WeakPolarHBondContact NE2-CE2 3.42Å; H349-F383 AromaticContact NE2-CZ 3.7Å; H349-T387 PolarHBondContact NE2-OG1 2.85Å; H349-L390 HydrophobicContact CB-CD1 3.4Å; H349-L390 VanDerWaalsContact CG-CD1 3.43Å; H349-Y399 AromaticContact CE1-CD1 3.75Å; H349-Y399 AromaticContact CE1-CE1 3.83Å; H349-Y399 AromaticContact ND1-CD1 3.99Å; H349-Y399 AromaticContact ND1-CE1 3.58Å
350E93.7Very high92.4Very high1 Ų125 Ų251%0.00512%0.118CC..Hα-helixtrans-61.8-39.9175.1176.964.2-171.500111.7I346 T348 Y353 Q354 Y398 R522 I525 R526I346-E350 WeakPolarHBondContact O-CB 3.48Å; I346-E350 PolarHBondContact O-N 3.18Å; I346-E350 VanDerWaalsContact O-N 3.1Å; T348-E350 PolarHBondContact O-N 2.85Å; E350-Y353 PolarHBondContact O-N 2.83Å; E350-Q354 WeakPolarHBondContact O-CG 3.48Å; E350-Q354 PolarHBondContact O-N 3.11Å; E350-Q354 PolarHBondContact OE1-NE2 3.16Å; E350-Y398 VanDerWaalsContact CD-OH 3.31Å; E350-Y398 PolarHBondContact OE1-OH 2.82Å; E350-Y398 WeakPolarHBondContact OE2-CE1 3.26Å; E350-Y398 VanDerWaalsContact OE2-CZ 3.24Å; E350-Y398 PolarHBondContact OE2-OH 3.32Å; E350-R522 HydrophobicContact CB-CG 4.03Å; E350-R522 HydrophobicContact CG-CB 3.9Å; E350-R522 HydrophobicContact CG-CG 3.92Å; E350-I525 HydrophobicContact CB-CG2 4.39Å; E350-I525 HydrophobicContact CG-CB 3.85Å; E350-I525 HydrophobicContact CG-CG2 3.84Å; E350-R526 WeakPolarHBondContact OE1-CB 3.41Å
351M93.3Very high92.6Very high1 Ų124.9 Ų24.91%0.00511%0.114CC..Hα-helixtrans-60-51.1174.2178.2-14664.100110.9P307 L308 M325 E347 T348 H349 Y353 Q354 V355 F366 F370 I525P307-M351 HydrophobicContact CB-CB 3.97Å; P307-M351 HydrophobicContact CB-CG 4.46Å; P307-M351 HydrophobicContact CG-CB 4.32Å; P307-M351 HydrophobicContact CG-CG 4.4Å; P307-M351 VanDerWaalsContact O-SD 3.41Å; L308-M351 HydrophobicContact CD2-SD 3.71Å; M325-M351 HydrophobicContact SD-CE 4.48Å; M325-M351 HydrophobicContact SD-SD 4.46Å; E347-M351 PolarHBondContact O-N 3.37Å; T348-M351 WeakPolarHBondContact O-CB 3.48Å; T348-M351 PolarHBondContact O-N 3.22Å; H349-M351 VanDerWaalsContact C-N 3.32Å; H349-M351 PolarHBondContact O-N 3.02Å; M351-Y353 VanDerWaalsContact C-N 3.3Å; M351-Y353 PolarHBondContact O-N 2.6Å; M351-Q354 PolarHBondContact O-N 3.37Å; M351-Q354 VanDerWaalsContact O-N 3.17Å; M351-V355 WeakPolarHBondContact O-CG2 3.44Å; M351-V355 PolarHBondContact O-N 3.4Å; M351-F366 HydrophobicContact CE-CE2 4.03Å; M351-F366 HydrophobicContact CE-CZ 3.91Å; M351-F366 HydrophobicContact SD-CE2 4.38Å; M351-F370 HydrophobicContact CG-CD1 4.32Å; M351-F370 HydrophobicContact CG-CE1 3.49Å; M351-F370 VanDerWaalsContact CG-CE1 3.49Å; M351-F370 HydrophobicContact CG-CZ 4.07Å; M351-F370 HydrophobicContact SD-CE1 3.75Å; M351-I525 HydrophobicContact CB-CG2 4.17Å
352L95.4Very high92.8Very high0 Ų022.8 Ų22.80%010%0.102CC..Hα-helixtrans-56.6-44.4177.1-66.5166.2000111.3L329 A330 P333 T348 H349 Q354 V355 T356 L362 F366 F383L329-L352 HydrophobicContact CD1-CD1 4.37Å; L329-L352 HydrophobicContact CD1-CD2 4.06Å; A330-L352 HydrophobicContact CB-CD1 3.76Å; A330-L352 HydrophobicContact CB-CD2 4.38Å; P333-L352 HydrophobicContact CG-CD1 4.3Å; T348-L352 HydrophobicContact CG2-CD1 4.41Å; T348-L352 WeakPolarHBondContact O-CG 3.17Å; T348-L352 PolarHBondContact O-N 2.81Å; T348-L352 VanDerWaalsContact O-N 3.08Å; H349-L352 PolarHBondContact O-N 3.28Å; L352-Q354 VanDerWaalsContact C-N 3.34Å; L352-Q354 PolarHBondContact O-N 2.9Å; L352-V355 WeakPolarHBondContact O-CB 3.26Å; L352-V355 PolarHBondContact O-N 2.92Å; L352-V355 VanDerWaalsContact O-N 3.13Å; L352-T356 PolarHBondContact O-N 3.16Å; L352-T356 PolarHBondContact O-OG1 3.24Å; L352-T356 VanDerWaalsContact O-OG1 3.12Å; L352-L362 HydrophobicContact CD2-CD1 3.84Å; L352-L362 HydrophobicContact CD2-CD2 3.96Å; L352-F366 HydrophobicContact CD2-CE1 4.27Å; L352-F366 HydrophobicContact CD2-CZ 3.87Å; L352-F383 HydrophobicContact CB-CD2 3.82Å; L352-F383 HydrophobicContact CB-CE2 3.76Å; L352-F383 HydrophobicContact CD1-CD2 4.43Å
353Y95.4Very high93.1Very high5 Ų522.3 Ų22.32%0.0210%0.1CC..Hα-helixtrans-63.5-36.1178.9-171.2-161.7000112.9H349 E350 M351 K357 F383 Y398 E401 A402 T405H349-Y353 WeakPolarHBondContact O-CB 3.46Å; H349-Y353 PolarHBondContact O-N 2.85Å; E350-Y353 PolarHBondContact O-N 2.83Å; M351-Y353 VanDerWaalsContact C-N 3.3Å; M351-Y353 PolarHBondContact O-N 2.6Å; Y353-K357 HydrophobicContact CD2-CD 4.15Å; Y353-K357 HydrophobicContact CD2-CG 4.22Å; Y353-K357 HydrophobicContact CE2-CD 3.96Å; Y353-K357 HydrophobicContact CE2-CG 4.11Å; Y353-K357 WeakPolarHBondContact O-CB 3.35Å; Y353-K357 WeakPolarHBondContact O-CG 3.23Å; Y353-K357 PolarHBondContact O-N 3.22Å; Y353-K357 WeakPolarHBondContact OH-CE 3.41Å; Y353-K357 PolarHBondContact OH-NZ 2.68Å; Y353-F383 HydrophobicContact CD2-CE1 4.44Å; Y353-F383 AromaticContact CD2-CZ 3.98Å; Y353-F383 HydrophobicContact CD2-CZ 3.98Å; Y353-F383 HydrophobicContact CG-CZ 4.07Å; Y353-Y398 AromaticContact CD1-CE1 3.62Å; Y353-Y398 HydrophobicContact CD1-CE1 3.62Å; Y353-Y398 AromaticContact CD1-CZ 3.75Å; Y353-Y398 WeakPolarHBondContact CD1-OH 3.47Å; Y353-Y398 HydrophobicContact CE1-CD1 4.33Å; Y353-Y398 AromaticContact CE1-CE1 3.58Å; Y353-Y398 HydrophobicContact CE1-CE1 3.58Å; Y353-Y398 HydrophobicContact CE1-CE2 4.18Å; Y353-Y398 AromaticContact CE1-CZ 3.5Å; Y353-Y398 VanDerWaalsContact CE1-CZ 3.5Å; Y353-E401 PolarHBondContact OH-O 3.36Å; Y353-A402 HydrophobicContact CD1-CB 4.2Å; Y353-A402 HydrophobicContact CD2-CB 4.33Å; Y353-A402 HydrophobicContact CE1-CB 3.71Å; Y353-A402 HydrophobicContact CE2-CB 3.9Å; Y353-A402 HydrophobicContact CG-CB 4.48Å; Y353-A402 VanDerWaalsContact CZ-CA 3.42Å; Y353-A402 WeakPolarHBondContact OH-CA 3.4Å; Y353-A402 PolarHBondContact OH-N 2.88Å; Y353-T405 HydrophobicContact CE2-CG2 4.26Å; Y353-T405 PolarHBondContact OH-OG1 2.69Å
354Q92.8Very high93.4Very high18 Ų1817.2 Ų17.28%0.0848%0.082CC..Hα-helixtrans-72.1-32.5173.7-63.9-54.4-24.700112.6E350 M351 L352 K357 K358 V529E350-Q354 WeakPolarHBondContact O-CG 3.48Å; E350-Q354 PolarHBondContact O-N 3.11Å; E350-Q354 PolarHBondContact OE1-NE2 3.16Å; M351-Q354 PolarHBondContact O-N 3.37Å; M351-Q354 VanDerWaalsContact O-N 3.17Å; L352-Q354 VanDerWaalsContact C-N 3.34Å; L352-Q354 PolarHBondContact O-N 2.9Å; Q354-K357 PolarHBondContact O-N 3.47Å; Q354-K358 WeakPolarHBondContact O-CB 3.17Å; Q354-K358 PolarHBondContact O-N 3.22Å; Q354-K358 VanDerWaalsContact O-N 3.08Å; Q354-V529 HydrophobicContact CB-CB 3.93Å; Q354-V529 HydrophobicContact CB-CG1 4.37Å; Q354-V529 HydrophobicContact CB-CG2 3.47Å; Q354-V529 VanDerWaalsContact CB-CG2 3.47Å; Q354-V529 HydrophobicContact CG-CG2 4.41Å
355V93.1Very high93.6Very high0 Ų016.4 Ų16.40%08%0.077CC..Hα-helixtrans-64.7-48.6170.4179.20000110.3M351 L352 K357 K358 H359 L362 P363 F366 F370M351-V355 WeakPolarHBondContact O-CG2 3.44Å; M351-V355 PolarHBondContact O-N 3.4Å; L352-V355 WeakPolarHBondContact O-CB 3.26Å; L352-V355 PolarHBondContact O-N 2.92Å; L352-V355 VanDerWaalsContact O-N 3.13Å; V355-K357 VanDerWaalsContact C-N 3.32Å; V355-K357 PolarHBondContact O-N 2.78Å; V355-K358 WeakPolarHBondContact O-CB 3.47Å; V355-K358 PolarHBondContact O-N 2.64Å; V355-H359 PolarHBondContact O-CD2 3.08Å; V355-H359 PolarHBondContact O-N 3.17Å; V355-H359 VanDerWaalsContact O-N 3.09Å; V355-L362 HydrophobicContact CB-CD1 4.08Å; V355-L362 HydrophobicContact CG1-CD1 3.84Å; V355-P363 HydrophobicContact CG1-CG 4.24Å; V355-F366 HydrophobicContact CG1-CD1 4.44Å; V355-F366 HydrophobicContact CG1-CD2 4.39Å; V355-F366 HydrophobicContact CG1-CG 4.24Å; V355-F366 HydrophobicContact CG2-CD2 4.09Å; V355-F366 HydrophobicContact CG2-CE2 3.99Å; V355-F370 HydrophobicContact CG2-CB 4.21Å; V355-F370 HydrophobicContact CG2-CD1 3.67Å; V355-F370 HydrophobicContact CG2-CG 4.27Å
356T94Very high93.6Very high7 Ų716.4 Ų16.44%0.0438%0.077CC..Hα-helixtrans-58.7-39.5175.3-59.80000112L352 K358 N360 F383L352-T356 PolarHBondContact O-N 3.16Å; L352-T356 PolarHBondContact O-OG1 3.24Å; L352-T356 VanDerWaalsContact O-OG1 3.12Å; T356-K358 VanDerWaalsContact C-N 3.34Å; T356-K358 PolarHBondContact O-N 2.89Å; T356-N360 CarbonylContact O-C 3.18Å; T356-N360 WeakPolarHBondContact O-CA 3.46Å; T356-N360 PolarHBondContact O-N 3.42Å; T356-F383 HydrophobicContact CG2-CE1 4.35Å
357K92.1Very high93.5Very high81 Ų8117.9 Ų17.935%0.3529%0.085SC..Hα-helixtrans-67.1-30.6174.1-84.5171.3169.4155.70114.1Y353 Q354 V355Y353-K357 HydrophobicContact CD2-CD 4.15Å; Y353-K357 HydrophobicContact CD2-CG 4.22Å; Y353-K357 HydrophobicContact CE2-CD 3.96Å; Y353-K357 HydrophobicContact CE2-CG 4.11Å; Y353-K357 WeakPolarHBondContact O-CB 3.35Å; Y353-K357 WeakPolarHBondContact O-CG 3.23Å; Y353-K357 PolarHBondContact O-N 3.22Å; Y353-K357 WeakPolarHBondContact OH-CE 3.41Å; Y353-K357 PolarHBondContact OH-NZ 2.68Å; Q354-K357 PolarHBondContact O-N 3.47Å; V355-K357 VanDerWaalsContact C-N 3.32Å; V355-K357 PolarHBondContact O-N 2.78Å
358K90.6Very high93.3Very high70 Ų7019.7 Ų19.730%0.30410%0.099SC..Hα-helixtrans-76.3-36.3179.4-176.3175.5-179.5177.60112.7Q354 V355 T356 F370 V529 S532Q354-K358 WeakPolarHBondContact O-CB 3.17Å; Q354-K358 PolarHBondContact O-N 3.22Å; Q354-K358 VanDerWaalsContact O-N 3.08Å; V355-K358 WeakPolarHBondContact O-CB 3.47Å; V355-K358 PolarHBondContact O-N 2.64Å; T356-K358 VanDerWaalsContact C-N 3.34Å; T356-K358 PolarHBondContact O-N 2.89Å; K358-F370 WeakPolarHBondContact CE-O 3.33Å; K358-F370 PolarHBondContact NZ-O 3.37Å; K358-V529 HydrophobicContact CB-CG1 4.24Å; K358-V529 HydrophobicContact CD-CG1 3.54Å; K358-V529 HydrophobicContact CG-CG1 4.48Å; K358-S532 PolarHBondContact NZ-OG 3.1Å
359H91.7Very high93Very high26 Ų2622 Ų2212%0.1211%0.11CC..Hα-helixtrans-116.28-173.5-51.5-66.5000114.1V355 F361 F370 V426V355-H359 PolarHBondContact O-CD2 3.08Å; V355-H359 PolarHBondContact O-N 3.17Å; V355-H359 VanDerWaalsContact O-N 3.09Å; H359-F361 PolarHBondContact O-N 3.26Å; H359-F370 PolarHBondContact NE2-O 3.35Å; H359-V426 HydrophobicContact CB-CG2 4.17Å
360N93.2Very high92.7Very high58 Ų5822.8 Ų22.831%0.3111%0.114SC..SBendtrans66.7-36.5-171.4-43.4-85.2000115T356 N409 F413T356-N360 CarbonylContact O-C 3.18Å; T356-N360 WeakPolarHBondContact O-CA 3.46Å; T356-N360 PolarHBondContact O-N 3.42Å; N360-N409 PolarHBondContact O-ND2 2.87Å; N360-F413 HydrophobicContact CB-CD2 4.06Å; N360-F413 HydrophobicContact CB-CE2 3.72Å; N360-F413 HydrophobicContact CB-CZ 4.31Å; N360-F413 WeakPolarHBondContact OD1-CE2 3.17Å; N360-F413 WeakPolarHBondContact OD1-CZ 3.27Å
361F95.1Very high92.4Very high14 Ų1430.3 Ų30.36%0.06114%0.142CC..SBendtrans-122.5164.9170.2-62.8-82.4000110.5H359 P363 H377 N409 L410 F413 A414 M423 V426H359-F361 PolarHBondContact O-N 3.26Å; F361-P363 VanDerWaalsContact O-CD 3.32Å; F361-P363 WeakPolarHBondContact O-CD 3.44Å; F361-H377 HydrophobicContact CB-CB 4.18Å; F361-H377 AromaticContact CD1-CD2 3.45Å; F361-H377 VanDerWaalsContact CD1-CD2 3.45Å; F361-H377 WeakPolarHBondContact CD1-CD2 3.36Å; F361-H377 AromaticContact CD1-NE2 3.42Å; F361-H377 WeakPolarHBondContact CD1-NE2 3.15Å; F361-H377 AromaticContact CG-CD2 3.69Å; F361-N409 HydrophobicContact CE1-CB 4.36Å; F361-N409 HydrophobicContact CZ-CB 4.35Å; F361-L410 HydrophobicContact CE1-CD2 4.12Å; F361-F413 HydrophobicContact CE2-CB 3.6Å; F361-F413 HydrophobicContact CE2-CD2 4.24Å; F361-F413 HydrophobicContact CE2-CG 4.26Å; F361-F413 HydrophobicContact CZ-CB 3.9Å; F361-A414 HydrophobicContact CZ-CB 4.17Å; F361-M423 HydrophobicContact CD2-CG 3.83Å; F361-M423 HydrophobicContact CE2-CG 3.69Å; F361-M423 HydrophobicContact CE2-SD 3.94Å; F361-M423 HydrophobicContact CZ-CG 4.27Å; F361-M423 HydrophobicContact CZ-SD 4.43Å; F361-V426 HydrophobicContact CB-CG1 3.86Å; F361-V426 HydrophobicContact CD2-CG1 4.27Å; F361-V426 HydrophobicContact CG-CG1 4.49Å
362L95.1Very high92.3Very high7 Ų731.2 Ų31.24%0.03715%0.148CC..  trans-76.1113.3167.4-170.966.9000107.9A330 L352 V355 F366 H377A330-L362 HydrophobicContact CB-CD2 3.83Å; L352-L362 HydrophobicContact CD2-CD1 3.84Å; L352-L362 HydrophobicContact CD2-CD2 3.96Å; V355-L362 HydrophobicContact CB-CD1 4.08Å; V355-L362 HydrophobicContact CG1-CD1 3.84Å; L362-F366 HydrophobicContact CD1-CD1 4.28Å; L362-F366 HydrophobicContact CD1-CE1 3.84Å; L362-F366 HydrophobicContact CD1-CZ 4.42Å; L362-H377 PolarHBondContact O-ND1 2.84Å
363P95.6Very high92.1Very high0 Ų035 Ų350%017%0.166CC..  trans-65.8144.5177.729.2-36.4000110.8V355 F361 A365 F366 V372 W374 V426V355-P363 HydrophobicContact CG1-CG 4.24Å; F361-P363 VanDerWaalsContact O-CD 3.32Å; F361-P363 WeakPolarHBondContact O-CD 3.44Å; P363-A365 PolarHBondContact O-N 3.21Å; P363-F366 HydrophobicContact CG-CB 3.97Å; P363-F366 HydrophobicContact CG-CD1 4.33Å; P363-V372 HydrophobicContact CB-CB 4.47Å; P363-V372 HydrophobicContact CB-CG1 4.05Å; P363-V372 HydrophobicContact CB-CG2 4.1Å; P363-V372 HydrophobicContact CG-CG2 4.19Å; P363-W374 WeakPolarHBondContact CB-O 3.31Å; P363-V426 HydrophobicContact CB-CG2 4.11Å
364E94.2Very high91.9Very high30 Ų3040.4 Ų40.414%0.1419%0.186CC..SBendtrans-52.4-28-177.3-163.775.5174.400113D326 S327 W374 Q376 P378 R380D326-E364 CarbonylContact C-O 3.54Å; D326-E364 WeakPolarHBondContact CA-O 3.47Å; S327-E364 PolarHBondContact N-O 3.46Å; S327-E364 PolarHBondContact OG-OE2 3.06Å; E364-W374 HydrophobicContact CB-CB 4.34Å; E364-Q376 HydrophobicContact CB-CB 4.15Å; E364-Q376 WeakPolarHBondContact CB-O 3.42Å; E364-Q376 PolarHBondContact N-O 2.67Å; E364-P378 WeakPolarHBondContact OE2-CD 3.44Å; E364-R380 IonicContact OE1-CZ 2.92Å; E364-R380 VanDerWaalsContact OE1-CZ 3.31Å; E364-R380 IonicContact OE1-NE 3.78Å; E364-R380 PolarHBondContact OE1-NE 2.96Å; E364-R380 IonicContact OE1-NH2 3.32Å; E364-R380 PolarHBondContact OE1-NH2 3.47Å; E364-R380 WeakPolarHBondContact OE2-CG 3.36Å; E364-R380 IonicContact OE2-NE 3.2Å; E364-R380 PolarHBondContact OE2-NE 2.97Å
365A94.3Very high91.8Very high0 Ų039.8 Ų39.80%018%0.184CC..EExtended strand (participates in β ladder)trans-147.1149.6159.400000113.3W324 M325 P363 H373 W374W324-A365 HydrophobicContact CD2-CB 4.39Å; W324-A365 HydrophobicContact CE3-CB 3.79Å; W324-A365 HydrophobicContact CZ3-CB 4.21Å; M325-A365 CarbonylContact O-C 3.6Å; M325-A365 WeakPolarHBondContact O-CA 3.43Å; M325-A365 WeakPolarHBondContact O-CB 3.5Å; P363-A365 PolarHBondContact O-N 3.21Å; A365-H373 HydrophobicContact CB-CB 4.04Å; A365-H373 WeakPolarHBondContact O-CA 3.42Å; A365-H373 WeakPolarHBondContact O-CB 3.4Å; A365-H373 PolarHBondContact O-N 3.48Å; A365-W374 HydrophobicContact CB-CB 4.03Å; A365-W374 HydrophobicContact CB-CD2 3.81Å; A365-W374 HydrophobicContact CB-CE3 3.54Å; A365-W374 HydrophobicContact CB-CG 4.05Å; A365-W374 HydrophobicContact CB-CZ3 4.29Å; A365-W374 PolarHBondContact N-O 3.37Å; A365-W374 PolarHBondContact O-N 3.14Å; A365-W374 VanDerWaalsContact O-N 3.1Å
366F93.6Very high91.8Very high0 Ų044 Ų440%020%0.204CC..EExtended strand (participates in β ladder)trans-139.3150.1176.858.6-77.9000114W324 M325 M351 L352 V355 L362 P363 F370 R371W324-F366 CarbonylContact C-O 3.49Å; W324-F366 VanDerWaalsContact CA-O 3.23Å; W324-F366 WeakPolarHBondContact CA-O 3.15Å; W324-F366 WeakPolarHBondContact CB-O 3.39Å; M325-F366 HydrophobicContact CB-CD1 4.49Å; M325-F366 HydrophobicContact CB-CE1 4.05Å; M325-F366 HydrophobicContact CB-CE2 4.18Å; M325-F366 HydrophobicContact CB-CZ 3.88Å; M325-F366 HydrophobicContact CE-CD2 3.79Å; M325-F366 HydrophobicContact CE-CE2 3.4Å; M325-F366 HydrophobicContact CE-CZ 4.16Å; M325-F366 PolarHBondContact N-O 3.47Å; M325-F366 PolarHBondContact O-N 3.31Å; M325-F366 HydrophobicContact SD-CE2 3.97Å; M325-F366 HydrophobicContact SD-CZ 4.18Å; M351-F366 HydrophobicContact CE-CE2 4.03Å; M351-F366 HydrophobicContact CE-CZ 3.91Å; M351-F366 HydrophobicContact SD-CE2 4.38Å; L352-F366 HydrophobicContact CD2-CE1 4.27Å; L352-F366 HydrophobicContact CD2-CZ 3.87Å; V355-F366 HydrophobicContact CG1-CD1 4.44Å; V355-F366 HydrophobicContact CG1-CD2 4.39Å; V355-F366 HydrophobicContact CG1-CG 4.24Å; V355-F366 HydrophobicContact CG2-CD2 4.09Å; V355-F366 HydrophobicContact CG2-CE2 3.99Å; L362-F366 HydrophobicContact CD1-CD1 4.28Å; L362-F366 HydrophobicContact CD1-CE1 3.84Å; L362-F366 HydrophobicContact CD1-CZ 4.42Å; P363-F366 HydrophobicContact CG-CB 3.97Å; P363-F366 HydrophobicContact CG-CD1 4.33Å; F366-F370 HydrophobicContact CD2-CD1 4.36Å; F366-F370 HydrophobicContact CE2-CD1 4.43Å; F366-R371 CarbonylContact C-O 3.6Å; F366-R371 WeakPolarHBondContact CA-O 3.36Å; F366-R371 VanDerWaalsContact CB-O 3.26Å; F366-R371 WeakPolarHBondContact CB-O 3.26Å
367T90.5Very high91.9Very high30 Ų3044 Ų4418%0.18420%0.203CC..EExtended strand (participates in β ladder)trans-78.6164177.553.80000112.6D369 F370 R371 H373T367-D369 PolarHBondContact O-N 3.06Å; T367-D369 VanDerWaalsContact O-N 3.1Å; T367-D369 PolarHBondContact OG1-OD1 3.08Å; T367-F370 WeakPolarHBondContact O-CA 3.27Å; T367-F370 PolarHBondContact O-N 3.11Å; T367-R371 PolarHBondContact N-O 2.88Å; T367-R371 WeakPolarHBondContact OG1-CB 3.36Å; T367-R371 PolarHBondContact OG1-N 2.84Å; T367-R371 PolarHBondContact OG1-O 3.44Å; T367-H373 HydrophobicContact CG2-CB 4.44Å
368T87.4Confident92Very high63 Ų6340.6 Ų40.639%0.38719%0.19SC..THydrogen-bonded Turntrans-60-16.1176.753.50000115.4L308 L310L308-T368 HydrophobicContact CD1-CG2 4.01Å; L310-T368 HydrophobicContact CD1-CG2 3.91Å; L310-T368 HydrophobicContact CD2-CG2 3.8Å; L310-T368 HydrophobicContact CG-CG2 4.48Å
369D85.4Confident92.3Very high49 Ų4937.3 Ų37.326%0.26218%0.175SC..THydrogen-bonded Turntrans-99.512.7172.780.4-38.6000113.8T367 R371 S532T367-D369 PolarHBondContact O-N 3.06Å; T367-D369 VanDerWaalsContact O-N 3.1Å; T367-D369 PolarHBondContact OG1-OD1 3.08Å; D369-R371 IonicContact OD1-NE 2.73Å; D369-R371 IonicContact OD2-CZ 2.87Å; D369-R371 IonicContact OD2-NE 3.2Å; D369-R371 PolarHBondContact OD2-NE 3.1Å; D369-R371 IonicContact OD2-NH2 2.89Å; D369-R371 PolarHBondContact OD2-NH2 2.93Å; D369-S532 PolarHBondContact O-OG 3.05Å
370F89.3Confident92.5Very high18 Ų1838.3 Ų38.38%0.07918%0.178CC..SBendtrans66.141.8174.8-43.1-67.1000113.7L308 M351 V355 K358 H359 F366 T367 V529L308-F370 HydrophobicContact CD2-CE1 3.95Å; L308-F370 HydrophobicContact CD2-CZ 4.04Å; M351-F370 HydrophobicContact CG-CD1 4.32Å; M351-F370 HydrophobicContact CG-CE1 3.49Å; M351-F370 VanDerWaalsContact CG-CE1 3.49Å; M351-F370 HydrophobicContact CG-CZ 4.07Å; M351-F370 HydrophobicContact SD-CE1 3.75Å; V355-F370 HydrophobicContact CG2-CB 4.21Å; V355-F370 HydrophobicContact CG2-CD1 3.67Å; V355-F370 HydrophobicContact CG2-CG 4.27Å; K358-F370 WeakPolarHBondContact CE-O 3.33Å; K358-F370 PolarHBondContact NZ-O 3.37Å; H359-F370 PolarHBondContact NE2-O 3.35Å; F366-F370 HydrophobicContact CD2-CD1 4.36Å; F366-F370 HydrophobicContact CE2-CD1 4.43Å; T367-F370 WeakPolarHBondContact O-CA 3.27Å; T367-F370 PolarHBondContact O-N 3.11Å; F370-V529 HydrophobicContact CB-CG1 4.17Å; F370-V529 HydrophobicContact CB-CG2 4.41Å; F370-V529 HydrophobicContact CD1-CG2 4.34Å; F370-V529 HydrophobicContact CD2-CB 4.28Å; F370-V529 HydrophobicContact CD2-CG2 3.69Å; F370-V529 HydrophobicContact CE2-CG2 3.99Å; F370-V529 HydrophobicContact CG-CG1 4.49Å; F370-V529 HydrophobicContact CG-CG2 3.87Å; F370-V529 HydrophobicContact CZ-CG2 4.44Å
371R88.2Confident92.8Very high159 Ų15935.7 Ų35.760%0.616%0.164SC*.  trans-102.7152.3165.7-56.3-175.3-155.6-179.616.1110.3F366 T367 D369 H373F366-R371 CarbonylContact C-O 3.6Å; F366-R371 WeakPolarHBondContact CA-O 3.36Å; F366-R371 VanDerWaalsContact CB-O 3.26Å; F366-R371 WeakPolarHBondContact CB-O 3.26Å; T367-R371 PolarHBondContact N-O 2.88Å; T367-R371 WeakPolarHBondContact OG1-CB 3.36Å; T367-R371 PolarHBondContact OG1-N 2.84Å; T367-R371 PolarHBondContact OG1-O 3.44Å; D369-R371 IonicContact OD1-NE 2.73Å; D369-R371 IonicContact OD2-CZ 2.87Å; D369-R371 IonicContact OD2-NE 3.2Å; D369-R371 PolarHBondContact OD2-NE 3.1Å; D369-R371 IonicContact OD2-NH2 2.89Å; D369-R371 PolarHBondContact OD2-NH2 2.93Å; R371-H373 PolarHBondContact O-N 2.65Å
372V90.9Very high92.9Very high21 Ų2136 Ų3613%0.12717%0.166CC..EExtended strand (participates in β ladder)trans-62.9123.3172.81790000109.8P363 W374 A375 V426 R427P363-V372 HydrophobicContact CB-CB 4.47Å; P363-V372 HydrophobicContact CB-CG1 4.05Å; P363-V372 HydrophobicContact CB-CG2 4.1Å; P363-V372 HydrophobicContact CG-CG2 4.19Å; V372-W374 WeakPolarHBondContact CG1-O 3.43Å; V372-A375 VanDerWaalsContact CG1-CA 3.41Å; V372-A375 HydrophobicContact CG1-CB 3.57Å; V372-V426 HydrophobicContact CG2-CG2 4.16Å; V372-R427 HydrophobicContact CB-CG 4.33Å; V372-R427 HydrophobicContact CG1-CG 4.42Å; V372-R427 HydrophobicContact CG2-CG 3.87Å
373H91.6Very high93.1Very high80 Ų8036.2 Ų36.237%0.3717%0.167SC..EExtended strand (participates in β ladder)trans-93.3-55.8168.9-172.961.9000109.8W324 A365 T367 R371W324-H373 HydrophobicContact CB-CB 4.32Å; W324-H373 AromaticContact CD1-CD2 3.6Å; W324-H373 AromaticContact CD1-CE1 3.95Å; W324-H373 AromaticContact CD1-NE2 3.47Å; W324-H373 AromaticContact CD2-CD2 3.94Å; W324-H373 AromaticContact CG-CD2 3.67Å; W324-H373 AromaticContact NE1-CD2 3.8Å; W324-H373 AromaticContact NE1-NE2 3.46Å; W324-H373 PolarHBondContact NE1-NE2 3.23Å; A365-H373 HydrophobicContact CB-CB 4.04Å; A365-H373 WeakPolarHBondContact O-CA 3.42Å; A365-H373 WeakPolarHBondContact O-CB 3.4Å; A365-H373 PolarHBondContact O-N 3.48Å; T367-H373 HydrophobicContact CG2-CB 4.44Å; R371-H373 PolarHBondContact O-N 2.65Å
374W90.4Very high93.2Very high117 Ų11736.3 Ų36.344%0.44317%0.167SC..EExtended strand (participates in β ladder)trans-114.6131.2169.3-60-28.2000108.6W324 P363 E364 A365 V372W324-W374 AromaticContact CH2-CH2 3.35Å; W324-W374 HydrophobicContact CH2-CH2 3.35Å; W324-W374 HydrophobicContact CH2-CZ2 4.15Å; W324-W374 AromaticContact CH2-CZ3 3.63Å; W324-W374 HydrophobicContact CH2-CZ3 3.63Å; W324-W374 AromaticContact CZ2-CH2 3.54Å; W324-W374 HydrophobicContact CZ2-CH2 3.54Å; W324-W374 AromaticContact CZ2-CZ2 3.89Å; W324-W374 HydrophobicContact CZ2-CZ2 3.89Å; W324-W374 HydrophobicContact CZ2-CZ3 4.22Å; W324-W374 HydrophobicContact CZ3-CH2 4.12Å; W324-W374 AromaticContact CZ3-CZ3 3.95Å; W324-W374 HydrophobicContact CZ3-CZ3 3.95Å; P363-W374 WeakPolarHBondContact CB-O 3.31Å; E364-W374 HydrophobicContact CB-CB 4.34Å; A365-W374 HydrophobicContact CB-CB 4.03Å; A365-W374 HydrophobicContact CB-CD2 3.81Å; A365-W374 HydrophobicContact CB-CE3 3.54Å; A365-W374 HydrophobicContact CB-CG 4.05Å; A365-W374 HydrophobicContact CB-CZ3 4.29Å; A365-W374 PolarHBondContact N-O 3.37Å; A365-W374 PolarHBondContact O-N 3.14Å; A365-W374 VanDerWaalsContact O-N 3.1Å; V372-W374 WeakPolarHBondContact CG1-O 3.43Å
375A92.3Very high93.4Very high6 Ų635.2 Ų35.25%0.0516%0.162CC..  trans-97.2-6.2-163.400000114.5V372 D425 V426V372-A375 VanDerWaalsContact CG1-CA 3.41Å; V372-A375 HydrophobicContact CG1-CB 3.57Å; A375-D425 HydrophobicContact CB-CB 4.04Å; A375-D425 VanDerWaalsContact CB-CG 3.49Å; A375-D425 WeakPolarHBondContact CB-OD1 3.12Å; A375-D425 CarbonylContact O-C 3.3Å; A375-D425 VanDerWaalsContact O-CA 3.27Å; A375-D425 WeakPolarHBondContact O-CA 3.44Å; A375-V426 WeakPolarHBondContact O-CG1 3.41Å; A375-V426 PolarHBondContact O-N 2.91Å
376Q93Very high93.6Very high87 Ų8735.2 Ų35.241%0.40716%0.162SC..  trans-62.3157.3175.3-63.984.4-21.700110.9E364 M423E364-Q376 HydrophobicContact CB-CB 4.15Å; E364-Q376 WeakPolarHBondContact CB-O 3.42Å; E364-Q376 PolarHBondContact N-O 2.67Å; Q376-M423 CarbonylContact C-O 3.54Å; Q376-M423 WeakPolarHBondContact CA-O 3.22Å
377H95.8Very high93.8Very high8 Ų835.2 Ų35.24%0.03716%0.162CC..BIsolated β-bridgetrans-155.596.4163.4175.982.7000108.5F361 L362 L379 M423 V426F361-H377 HydrophobicContact CB-CB 4.18Å; F361-H377 AromaticContact CD1-CD2 3.45Å; F361-H377 VanDerWaalsContact CD1-CD2 3.45Å; F361-H377 WeakPolarHBondContact CD1-CD2 3.36Å; F361-H377 AromaticContact CD1-NE2 3.42Å; F361-H377 WeakPolarHBondContact CD1-NE2 3.15Å; F361-H377 AromaticContact CG-CD2 3.69Å; L362-H377 PolarHBondContact O-ND1 2.84Å; H377-L379 PolarHBondContact O-N 3.43Å; H377-M423 HydrophobicContact CB-CB 4.19Å; H377-M423 PolarHBondContact N-O 3.22Å; H377-M423 PolarHBondContact O-N 3.15Å; H377-V426 HydrophobicContact CB-CG1 3.75Å
378P94.6Very high94.2Very high10 Ų1034.3 Ų34.37%0.06516%0.155CC..  trans-79.746.2-18035.2-35.8000112.1E364 R380 A422 F438E364-P378 WeakPolarHBondContact OE2-CD 3.44Å; P378-R380 VanDerWaalsContact C-N 3.25Å; P378-R380 HydrophobicContact CG-CG 3.98Å; P378-R380 PolarHBondContact O-N 2.85Å; P378-A422 HydrophobicContact CB-CB 4.4Å; P378-F438 WeakPolarHBondContact O-CE2 3.09Å; P378-F438 WeakPolarHBondContact O-CZ 3.36Å
379L96.9Very high94.6Very high1 Ų132.2 Ų32.21%0.00514%0.141CC..  trans60.429.2177.5-44.4179.5000115.2H377 L410 A414 F420 M435 F439 M443H377-L379 PolarHBondContact O-N 3.43Å; L379-L410 HydrophobicContact CD2-CD2 4.17Å; L379-A414 HydrophobicContact CD2-CB 3.74Å; L379-F420 HydrophobicContact CD1-CB 3.89Å; L379-M435 HydrophobicContact CD1-CG 4.5Å; L379-F439 HydrophobicContact CB-CD2 3.41Å; L379-F439 VanDerWaalsContact CB-CD2 3.41Å; L379-F439 HydrophobicContact CB-CE2 3.84Å; L379-F439 HydrophobicContact CB-CG 4.1Å; L379-F439 HydrophobicContact CD1-CB 4.47Å; L379-F439 HydrophobicContact CD1-CD1 4.01Å; L379-F439 HydrophobicContact CD1-CD2 3.74Å; L379-F439 HydrophobicContact CD1-CE1 4.18Å; L379-F439 HydrophobicContact CD1-CE2 3.92Å; L379-F439 HydrophobicContact CD1-CG 3.78Å; L379-F439 HydrophobicContact CD1-CZ 4.14Å; L379-F439 HydrophobicContact CG-CD2 4.17Å; L379-F439 HydrophobicContact CG-CE2 4.37Å; L379-M443 WeakPolarHBondContact O-CG 3.47Å
380R95.9Very high95.1Very high47 Ų4729.9 Ų29.918%0.17713%0.129CC..  trans-39.6116.2179.6-76.5-75.6176.8-149-0.8115.2E364 P378 E382 M443E364-R380 IonicContact OE1-CZ 2.92Å; E364-R380 VanDerWaalsContact OE1-CZ 3.31Å; E364-R380 IonicContact OE1-NE 3.78Å; E364-R380 PolarHBondContact OE1-NE 2.96Å; E364-R380 IonicContact OE1-NH2 3.32Å; E364-R380 PolarHBondContact OE1-NH2 3.47Å; E364-R380 WeakPolarHBondContact OE2-CG 3.36Å; E364-R380 IonicContact OE2-NE 3.2Å; E364-R380 PolarHBondContact OE2-NE 2.97Å; P378-R380 VanDerWaalsContact C-N 3.25Å; P378-R380 HydrophobicContact CG-CG 3.98Å; P378-R380 PolarHBondContact O-N 2.85Å; R380-E382 WeakPolarHBondContact CA-OE2 3.38Å; R380-E382 WeakPolarHBondContact CB-OE2 3.47Å; R380-E382 WeakPolarHBondContact CD-OE1 3.2Å; R380-E382 IonicContact NH1-OE1 3.35Å; R380-M443 WeakPolarHBondContact O-CE 3.48Å
381P97.9Very high95.4Very high2 Ų231.3 Ų31.31%0.01313%0.134CC..  trans-82.8-17.1-170.830.7-33.3000115.8F383 A384 E385 F438 E442 M443P381-F383 VanDerWaalsContact C-N 3.27Å; P381-F383 PolarHBondContact O-N 3.07Å; P381-F383 VanDerWaalsContact O-N 3.16Å; P381-A384 WeakPolarHBondContact O-CA 3.38Å; P381-A384 VanDerWaalsContact O-CB 3.29Å; P381-A384 WeakPolarHBondContact O-CB 3.31Å; P381-A384 PolarHBondContact O-N 3.36Å; P381-E385 PolarHBondContact O-N 2.67Å; P381-E385 VanDerWaalsContact O-N 3.07Å; P381-F438 HydrophobicContact CG-CD2 4.19Å; P381-E442 HydrophobicContact CB-CB 3.56Å; P381-E442 HydrophobicContact CB-CG 4.45Å; P381-E442 HydrophobicContact CG-CB 3.83Å; P381-E442 VanDerWaalsContact CG-CD 3.43Å; P381-E442 HydrophobicContact CG-CG 4.22Å; P381-E442 WeakPolarHBondContact CG-OE1 3.49Å; P381-M443 HydrophobicContact CB-CB 4.49Å; P381-M443 HydrophobicContact CB-CG 3.95Å
382E98.4Very high95.6Very high22 Ų2228.7 Ų28.710%0.10313%0.127CC..Hα-helixtrans-64.4-30.7-163.1-48.488.2156.900112.3A330 F331 R380 S386A330-E382 CarbonylContact C-O 3.54Å; A330-E382 HydrophobicContact CB-CB 4.1Å; A330-E382 VanDerWaalsContact O-O 3.06Å; F331-E382 HydrophobicContact CB-CB 3.99Å; F331-E382 HydrophobicContact CB-CG 4.36Å; R380-E382 WeakPolarHBondContact CA-OE2 3.38Å; R380-E382 WeakPolarHBondContact CB-OE2 3.47Å; R380-E382 WeakPolarHBondContact CD-OE1 3.2Å; R380-E382 IonicContact NH1-OE1 3.35Å; E382-S386 PolarHBondContact O-N 3.24Å; E382-S386 VanDerWaalsContact O-N 3.11Å
383F98.1Very high95.6Very high11 Ų1128.6 Ų28.65%0.04813%0.128CC..Hα-helixtrans-71.3-28.1172.5-177.7-110.6000113A330 H349 L352 Y353 T356 P381 T387 I406A330-F383 HydrophobicContact CB-CB 4.04Å; H349-F383 AromaticContact CD2-CE2 3.64Å; H349-F383 AromaticContact CE1-CE2 3.82Å; H349-F383 AromaticContact CE1-CZ 3.92Å; H349-F383 AromaticContact NE2-CD2 4Å; H349-F383 AromaticContact NE2-CE2 3.33Å; H349-F383 VanDerWaalsContact NE2-CE2 3.33Å; H349-F383 WeakPolarHBondContact NE2-CE2 3.42Å; H349-F383 AromaticContact NE2-CZ 3.7Å; L352-F383 HydrophobicContact CB-CD2 3.82Å; L352-F383 HydrophobicContact CB-CE2 3.76Å; L352-F383 HydrophobicContact CD1-CD2 4.43Å; Y353-F383 HydrophobicContact CD2-CE1 4.44Å; Y353-F383 AromaticContact CD2-CZ 3.98Å; Y353-F383 HydrophobicContact CD2-CZ 3.98Å; Y353-F383 HydrophobicContact CG-CZ 4.07Å; T356-F383 HydrophobicContact CG2-CE1 4.35Å; P381-F383 VanDerWaalsContact C-N 3.27Å; P381-F383 PolarHBondContact O-N 3.07Å; P381-F383 VanDerWaalsContact O-N 3.16Å; F383-T387 WeakPolarHBondContact O-CB 3.44Å; F383-T387 PolarHBondContact O-N 2.78Å; F383-T387 PolarHBondContact O-OG1 2.99Å; F383-I406 HydrophobicContact CD1-CD1 3.65Å; F383-I406 HydrophobicContact CD1-CG1 4.09Å; F383-I406 HydrophobicContact CE1-CD1 3.83Å; F383-I406 HydrophobicContact CE1-CG1 4.06Å
384A98.4Very high95.5Very high2 Ų226.4 Ų26.42%0.01712%0.121CC..Hα-helixtrans-75.4-41172.800000111.3P381 T387 Y388 I406 M443 L447P381-A384 WeakPolarHBondContact O-CA 3.38Å; P381-A384 VanDerWaalsContact O-CB 3.29Å; P381-A384 WeakPolarHBondContact O-CB 3.31Å; P381-A384 PolarHBondContact O-N 3.36Å; A384-T387 WeakPolarHBondContact O-CB 3.18Å; A384-T387 PolarHBondContact O-N 3.36Å; A384-Y388 PolarHBondContact O-N 3.41Å; A384-I406 HydrophobicContact CB-CD1 4.11Å; A384-M443 HydrophobicContact CB-SD 3.86Å; A384-L447 HydrophobicContact CB-CD2 4.3Å; A384-L447 HydrophobicContact CB-CG 4.27Å
385E98.4Very high95.4Very high7 Ų723.2 Ų23.23%0.03312%0.124CC..Hα-helixtrans-52.2-58.4171.3-178.1-160.7-166.200111F331 P381 T387 Y388 F389 Y446F331-E385 WeakPolarHBondContact CA-OE2 3.49Å; F331-E385 VanDerWaalsContact CB-OE2 3.31Å; F331-E385 WeakPolarHBondContact CB-OE2 3.23Å; P381-E385 PolarHBondContact O-N 2.67Å; P381-E385 VanDerWaalsContact O-N 3.07Å; E385-T387 PolarHBondContact O-N 3.21Å; E385-Y388 WeakPolarHBondContact O-CA 3.44Å; E385-Y388 WeakPolarHBondContact O-CB 3.35Å; E385-Y388 PolarHBondContact O-N 3.01Å; E385-F389 HydrophobicContact CG-CD2 3.72Å; E385-F389 HydrophobicContact CG-CE2 3.58Å; E385-F389 PolarHBondContact O-N 3.23Å; E385-F389 WeakPolarHBondContact OE1-CE2 3.44Å; E385-Y446 HydrophobicContact CB-CD1 4.32Å; E385-Y446 HydrophobicContact CB-CD2 3.82Å; E385-Y446 HydrophobicContact CB-CE1 4.15Å; E385-Y446 HydrophobicContact CB-CE2 3.6Å; E385-Y446 HydrophobicContact CB-CG 4.17Å; E385-Y446 HydrophobicContact CG-CD1 4.33Å; E385-Y446 HydrophobicContact CG-CD2 4.48Å; E385-Y446 HydrophobicContact CG-CE1 3.78Å; E385-Y446 HydrophobicContact CG-CE2 3.94Å
386S98.2Very high95.3Very high0 Ų024.2 Ų24.20%013%0.128CC..Hα-helixtrans-59.6-33.6179.3-82.80000113.1A330 F331 P333 G334 E382 L390A330-S386 VanDerWaalsContact O-CB 3.26Å; A330-S386 WeakPolarHBondContact O-CB 3.32Å; A330-S386 PolarHBondContact O-OG 3.05Å; F331-S386 PolarHBondContact O-OG 2.97Å; P333-S386 WeakPolarHBondContact CD-OG 3.27Å; G334-S386 PolarHBondContact N-OG 3.07Å; E382-S386 PolarHBondContact O-N 3.24Å; E382-S386 VanDerWaalsContact O-N 3.11Å; S386-L390 VanDerWaalsContact O-CB 3.27Å; S386-L390 WeakPolarHBondContact O-CB 3.29Å; S386-L390 WeakPolarHBondContact O-CD1 3.31Å; S386-L390 WeakPolarHBondContact O-CG 3.37Å; S386-L390 PolarHBondContact O-N 3.28Å
387T98.4Very high95.1Very high0 Ų022.2 Ų22.20%012%0.123CC..Hα-helixtrans-65.9-40.8174.6-58.60000111.4H349 F383 A384 E385 Y391 Y399 A402 L450H349-T387 PolarHBondContact NE2-OG1 2.85Å; F383-T387 WeakPolarHBondContact O-CB 3.44Å; F383-T387 PolarHBondContact O-N 2.78Å; F383-T387 PolarHBondContact O-OG1 2.99Å; A384-T387 WeakPolarHBondContact O-CB 3.18Å; A384-T387 PolarHBondContact O-N 3.36Å; E385-T387 PolarHBondContact O-N 3.21Å; T387-Y391 WeakPolarHBondContact O-CB 3.36Å; T387-Y391 PolarHBondContact O-N 3.41Å; T387-Y399 VanDerWaalsContact CG2-O 3.26Å; T387-Y399 WeakPolarHBondContact CG2-O 3.08Å; T387-A402 HydrophobicContact CG2-CB 3.91Å; T387-L450 HydrophobicContact CG2-CD1 4.48Å; T387-L450 HydrophobicContact CG2-CD2 3.79Å
388Y97.9Very high94.9Very high11 Ų1123.7 Ų23.74%0.04313%0.128CC..Hα-helixtrans-64.3-53.1175.8166.4-111.7000112.1A384 E385 L390 Y391 K392 Y446 L449A384-Y388 PolarHBondContact O-N 3.41Å; E385-Y388 WeakPolarHBondContact O-CA 3.44Å; E385-Y388 WeakPolarHBondContact O-CB 3.35Å; E385-Y388 PolarHBondContact O-N 3.01Å; Y388-L390 PolarHBondContact O-N 3.36Å; Y388-Y391 PolarHBondContact O-N 2.78Å; Y388-Y391 VanDerWaalsContact O-N 3.16Å; Y388-K392 HydrophobicContact CE2-CB 4.5Å; Y388-K392 WeakPolarHBondContact O-CB 3.45Å; Y388-K392 PolarHBondContact O-N 3.03Å; Y388-Y446 AromaticContact CD1-CD1 3.97Å; Y388-Y446 HydrophobicContact CD1-CD1 3.97Å; Y388-Y446 HydrophobicContact CG-CD1 4.46Å; Y388-L449 HydrophobicContact CD2-CB 3.71Å; Y388-L449 HydrophobicContact CE1-CD1 4.2Å; Y388-L449 HydrophobicContact CE2-CB 3.41Å; Y388-L449 VanDerWaalsContact CE2-CB 3.41Å; Y388-L449 HydrophobicContact CE2-CD1 4.49Å; Y388-L449 HydrophobicContact CE2-CG 4.46Å; Y388-L449 HydrophobicContact CG-CB 4.38Å
389F97Very high95Very high19 Ų1923.2 Ų23.28%0.08313%0.125CC..Hα-helixtrans-61.7-42.5-179.8-77.4-65.2000112.4V337 L338 E385 Y391 K392 A393 F466V337-F389 HydrophobicContact CB-CB 4.14Å; V337-F389 HydrophobicContact CG1-CB 4Å; L338-F389 HydrophobicContact CD1-CZ 4.35Å; L338-F389 HydrophobicContact CD2-CD1 4.15Å; L338-F389 HydrophobicContact CD2-CE1 3.79Å; L338-F389 HydrophobicContact CD2-CZ 4.37Å; L338-F389 HydrophobicContact CG-CD1 4.45Å; L338-F389 HydrophobicContact CG-CE1 4.29Å; E385-F389 HydrophobicContact CG-CD2 3.72Å; E385-F389 HydrophobicContact CG-CE2 3.58Å; E385-F389 PolarHBondContact O-N 3.23Å; E385-F389 WeakPolarHBondContact OE1-CE2 3.44Å; F389-Y391 VanDerWaalsContact C-N 3.33Å; F389-Y391 PolarHBondContact O-N 3.05Å; F389-K392 PolarHBondContact O-N 3.19Å; F389-A393 PolarHBondContact O-N 3.36Å; F389-F466 HydrophobicContact CZ-CD2 4.37Å
390L95.8Very high94.9Very high0 Ų023.4 Ų23.40%013%0.126CC..Hα-helixtrans-62.5-37.6175.6-80.6166.3000112.6P333 V337 I342 A345 I346 H349 S386 Y388 T394 Y399P333-L390 HydrophobicContact CB-CD1 4.36Å; V337-L390 HydrophobicContact CG2-CD2 3.5Å; V337-L390 VanDerWaalsContact CG2-CD2 3.5Å; V337-L390 HydrophobicContact CG2-CG 3.8Å; I342-L390 HydrophobicContact CG2-CD2 4.17Å; A345-L390 HydrophobicContact CB-CD2 3.94Å; I346-L390 HydrophobicContact CG1-CD2 4.14Å; H349-L390 HydrophobicContact CB-CD1 3.4Å; H349-L390 VanDerWaalsContact CG-CD1 3.43Å; S386-L390 VanDerWaalsContact O-CB 3.27Å; S386-L390 WeakPolarHBondContact O-CB 3.29Å; S386-L390 WeakPolarHBondContact O-CD1 3.31Å; S386-L390 WeakPolarHBondContact O-CG 3.37Å; S386-L390 PolarHBondContact O-N 3.28Å; Y388-L390 PolarHBondContact O-N 3.36Å; L390-T394 WeakPolarHBondContact O-CB 3.48Å; L390-T394 WeakPolarHBondContact O-CG2 3.5Å; L390-T394 PolarHBondContact O-N 3.43Å; L390-T394 VanDerWaalsContact O-N 3.14Å; L390-T394 PolarHBondContact O-OG1 3.35Å; L390-Y399 HydrophobicContact CB-CD1 4.06Å; L390-Y399 HydrophobicContact CB-CD2 4.12Å; L390-Y399 HydrophobicContact CB-CE1 3.81Å; L390-Y399 HydrophobicContact CB-CE2 3.84Å; L390-Y399 HydrophobicContact CB-CG 4.22Å; L390-Y399 HydrophobicContact CD1-CE1 3.91Å; L390-Y399 HydrophobicContact CG-CE1 4.39Å
391Y95.3Very high94.9Very high48 Ų4824.8 Ų24.819%0.18814%0.135CC..Hα-helixtrans-65-50.1171.9-179.1-115.6000111.8T387 Y388 F389 A393 T394 G395 L400 L450T387-Y391 WeakPolarHBondContact O-CB 3.36Å; T387-Y391 PolarHBondContact O-N 3.41Å; Y388-Y391 PolarHBondContact O-N 2.78Å; Y388-Y391 VanDerWaalsContact O-N 3.16Å; F389-Y391 VanDerWaalsContact C-N 3.33Å; F389-Y391 PolarHBondContact O-N 3.05Å; Y391-A393 VanDerWaalsContact C-N 3.31Å; Y391-A393 PolarHBondContact O-N 2.99Å; Y391-T394 PolarHBondContact O-N 2.9Å; Y391-G395 WeakPolarHBondContact O-CA 3.33Å; Y391-G395 PolarHBondContact O-N 2.82Å; Y391-L400 HydrophobicContact CD1-CD2 4.27Å; Y391-L400 HydrophobicContact CD2-CD2 4.23Å; Y391-L400 HydrophobicContact CD2-CG 4.12Å; Y391-L400 HydrophobicContact CE1-CD2 3.92Å; Y391-L400 HydrophobicContact CE2-CD1 3.91Å; Y391-L400 HydrophobicContact CE2-CD2 3.9Å; Y391-L400 HydrophobicContact CE2-CG 3.71Å; Y391-L400 HydrophobicContact CG-CD2 4.41Å; Y391-L450 HydrophobicContact CD1-CD1 3.64Å; Y391-L450 HydrophobicContact CG-CD1 3.64Å
392K92.1Very high94.8Very high103 Ų10324.7 Ų24.745%0.44813%0.134SC..Hα-helixtrans-54.7-44.3-179.7-177.978.2-169.4-1470112Y388 F389 E462Y388-K392 HydrophobicContact CE2-CB 4.5Å; Y388-K392 WeakPolarHBondContact O-CB 3.45Å; Y388-K392 PolarHBondContact O-N 3.03Å; F389-K392 PolarHBondContact O-N 3.19Å; K392-E462 VanDerWaalsContact CE-OE1 3.32Å; K392-E462 WeakPolarHBondContact CE-OE1 3.45Å; K392-E462 WeakPolarHBondContact CE-OE2 3.23Å; K392-E462 IonicContact NZ-OE1 2.77Å; K392-E462 PolarHBondContact NZ-OE1 3.19Å; K392-E462 IonicContact NZ-OE2 2.76Å; K392-E462 PolarHBondContact NZ-OE2 3.41Å; K392-E462 VanDerWaalsContact NZ-OE2 3.16Å
393A90.6Very high94.8Very high20 Ų2023.7 Ų23.717%0.16513%0.129CC..Hα-helixtrans-76.2-38.3-178.600000114V337 I342 F389 Y391 T508V337-A393 HydrophobicContact CG1-CB 3.58Å; I342-A393 HydrophobicContact CD1-CB 4.45Å; F389-A393 PolarHBondContact O-N 3.36Å; Y391-A393 VanDerWaalsContact C-N 3.31Å; Y391-A393 PolarHBondContact O-N 2.99Å; A393-T508 WeakPolarHBondContact O-CB 3.41Å; A393-T508 VanDerWaalsContact O-CG2 3.31Å; A393-T508 WeakPolarHBondContact O-CG2 3.49Å; A393-T508 PolarHBondContact O-OG1 2.92Å
394T89.1Confident94.7Very high34 Ų3426.9 Ų26.921%0.20914%0.141CC..Hα-helixtrans-101.2-25.9-170.666.40000114.9I342 L390 Y391 D396 Y399 F512I342-T394 HydrophobicContact CG2-CG2 3.91Å; L390-T394 WeakPolarHBondContact O-CB 3.48Å; L390-T394 WeakPolarHBondContact O-CG2 3.5Å; L390-T394 PolarHBondContact O-N 3.43Å; L390-T394 VanDerWaalsContact O-N 3.14Å; L390-T394 PolarHBondContact O-OG1 3.35Å; Y391-T394 PolarHBondContact O-N 2.9Å; T394-D396 PolarHBondContact O-N 3.25Å; T394-D396 PolarHBondContact OG1-N 3.37Å; T394-Y399 WeakPolarHBondContact OG1-CE2 3.4Å; T394-F512 HydrophobicContact CG2-CE2 4.14Å; T394-F512 HydrophobicContact CG2-CZ 4.29Å
395G88.8Confident94.7Very high49 Ų4928.2 Ų28.251%0.50515%0.149SC..  trans65.79.7-169.100000114.9Y391 P397Y391-G395 WeakPolarHBondContact O-CA 3.33Å; Y391-G395 PolarHBondContact O-N 2.82Å; G395-P397 WeakPolarHBondContact O-CD 3.49Å
396D89.9Confident94.6Very high28 Ų2828.5 Ų28.515%0.1515%0.151CC..  trans-72.9118.9-175.6-174.6-19.3000111.1T394 Y398 Y399 R522T394-D396 PolarHBondContact O-N 3.25Å; T394-D396 PolarHBondContact OG1-N 3.37Å; D396-Y398 PolarHBondContact O-N 2.7Å; D396-Y398 WeakPolarHBondContact OD1-CB 3.21Å; D396-Y398 PolarHBondContact OD1-N 3.03Å; D396-Y399 HydrophobicContact CB-CD2 3.99Å; D396-Y399 HydrophobicContact CB-CE2 3.92Å; D396-Y399 WeakPolarHBondContact O-CD2 3.34Å; D396-Y399 PolarHBondContact O-N 3.22Å; D396-R522 IonicContact OD1-NH1 2.7Å; D396-R522 IonicContact OD2-CZ 3.34Å; D396-R522 IonicContact OD2-NH1 3.33Å; D396-R522 PolarHBondContact OD2-NH1 2.94Å; D396-R522 IonicContact OD2-NH2 3.94Å; D396-R522 PolarHBondContact OD2-NH2 3.1Å
397P90.2Very high94.6Very high44 Ų4428.5 Ų28.529%0.28615%0.151SC..THydrogen-bonded Turntrans-63.2-11.3-178.727.4-36.1000113.8A20 G395 Y399 L400 E401A20-P397 HydrophobicContact CB-CB 4.1Å; A20-P397 HydrophobicContact CB-CG 4.09Å; G395-P397 WeakPolarHBondContact O-CD 3.49Å; P397-Y399 PolarHBondContact O-N 3.35Å; P397-L400 HydrophobicContact CB-CD1 4.4Å; P397-L400 WeakPolarHBondContact O-CB 3.48Å; P397-L400 PolarHBondContact O-N 2.87Å; P397-L400 VanDerWaalsContact O-N 3.1Å; P397-E401 PolarHBondContact O-N 2.67Å
398Y91.4Very high94.6Very high40 Ų4031.8 Ų31.816%0.15717%0.168CC..Hα-helixtrans-55.5-33.8171.7-171.8-105.8000113.3E350 Y353 D396 E401 A402 R522E350-Y398 VanDerWaalsContact CD-OH 3.31Å; E350-Y398 PolarHBondContact OE1-OH 2.82Å; E350-Y398 WeakPolarHBondContact OE2-CE1 3.26Å; E350-Y398 VanDerWaalsContact OE2-CZ 3.24Å; E350-Y398 PolarHBondContact OE2-OH 3.32Å; Y353-Y398 AromaticContact CD1-CE1 3.62Å; Y353-Y398 HydrophobicContact CD1-CE1 3.62Å; Y353-Y398 AromaticContact CD1-CZ 3.75Å; Y353-Y398 WeakPolarHBondContact CD1-OH 3.47Å; Y353-Y398 HydrophobicContact CE1-CD1 4.33Å; Y353-Y398 AromaticContact CE1-CE1 3.58Å; Y353-Y398 HydrophobicContact CE1-CE1 3.58Å; Y353-Y398 HydrophobicContact CE1-CE2 4.18Å; Y353-Y398 AromaticContact CE1-CZ 3.5Å; Y353-Y398 VanDerWaalsContact CE1-CZ 3.5Å; D396-Y398 PolarHBondContact O-N 2.7Å; D396-Y398 WeakPolarHBondContact OD1-CB 3.21Å; D396-Y398 PolarHBondContact OD1-N 3.03Å; Y398-E401 PolarHBondContact O-N 2.65Å; Y398-A402 PolarHBondContact O-N 3.15Å; Y398-A402 VanDerWaalsContact O-N 3.07Å; Y398-R522 VanDerWaalsContact CD1-CZ 3.44Å
399Y95.7Very high94.5Very high0 Ų032.1 Ų32.10%017%0.171CC..Hα-helixtrans-75.4-26.6178.6-59.9-61000112.8H349 T387 L390 T394 D396 P397 A402 G403 R522H349-Y399 AromaticContact CE1-CD1 3.75Å; H349-Y399 AromaticContact CE1-CE1 3.83Å; H349-Y399 AromaticContact ND1-CD1 3.99Å; H349-Y399 AromaticContact ND1-CE1 3.58Å; T387-Y399 VanDerWaalsContact CG2-O 3.26Å; T387-Y399 WeakPolarHBondContact CG2-O 3.08Å; L390-Y399 HydrophobicContact CB-CD1 4.06Å; L390-Y399 HydrophobicContact CB-CD2 4.12Å; L390-Y399 HydrophobicContact CB-CE1 3.81Å; L390-Y399 HydrophobicContact CB-CE2 3.84Å; L390-Y399 HydrophobicContact CB-CG 4.22Å; L390-Y399 HydrophobicContact CD1-CE1 3.91Å; L390-Y399 HydrophobicContact CG-CE1 4.39Å; T394-Y399 WeakPolarHBondContact OG1-CE2 3.4Å; D396-Y399 HydrophobicContact CB-CD2 3.99Å; D396-Y399 HydrophobicContact CB-CE2 3.92Å; D396-Y399 WeakPolarHBondContact O-CD2 3.34Å; D396-Y399 PolarHBondContact O-N 3.22Å; P397-Y399 PolarHBondContact O-N 3.35Å; Y399-A402 WeakPolarHBondContact O-CB 3.47Å; Y399-A402 PolarHBondContact O-N 3.13Å; Y399-G403 PolarHBondContact O-N 2.95Å; Y399-R522 VanDerWaalsContact CZ-NH2 3.25Å; Y399-R522 PolarHBondContact OH-NH2 2.98Å
400L96.2Very high94.6Very high5 Ų531.2 Ų31.23%0.02617%0.167CC..Hα-helixtrans-65.5-40.2170-60.4174.9000111.1M21 K26 Y391 P397 A402 G403 R404 L450 F451M21-L400 HydrophobicContact CB-CD1 4.02Å; M21-L400 HydrophobicContact CE-CB 3.8Å; M21-L400 HydrophobicContact SD-CB 4.01Å; M21-L400 HydrophobicContact SD-CD1 4.36Å; K26-L400 HydrophobicContact CD-CD1 4Å; K26-L400 HydrophobicContact CD-CD2 4.43Å; K26-L400 HydrophobicContact CG-CD1 4.18Å; Y391-L400 HydrophobicContact CD1-CD2 4.27Å; Y391-L400 HydrophobicContact CD2-CD2 4.23Å; Y391-L400 HydrophobicContact CD2-CG 4.12Å; Y391-L400 HydrophobicContact CE1-CD2 3.92Å; Y391-L400 HydrophobicContact CE2-CD1 3.91Å; Y391-L400 HydrophobicContact CE2-CD2 3.9Å; Y391-L400 HydrophobicContact CE2-CG 3.71Å; Y391-L400 HydrophobicContact CG-CD2 4.41Å; P397-L400 HydrophobicContact CB-CD1 4.4Å; P397-L400 WeakPolarHBondContact O-CB 3.48Å; P397-L400 PolarHBondContact O-N 2.87Å; P397-L400 VanDerWaalsContact O-N 3.1Å; L400-A402 VanDerWaalsContact C-N 3.31Å; L400-A402 PolarHBondContact O-N 3.47Å; L400-G403 PolarHBondContact O-N 3.16Å; L400-R404 WeakPolarHBondContact O-CB 3.24Å; L400-R404 PolarHBondContact O-N 2.98Å; L400-L450 HydrophobicContact CD2-CD1 3.9Å; L400-L450 HydrophobicContact CD2-CG 4.14Å; L400-L450 VanDerWaalsContact CD2-O 3.23Å; L400-L450 WeakPolarHBondContact CD2-O 3.22Å; L400-F451 HydrophobicContact CB-CE1 4.15Å; L400-F451 HydrophobicContact CD2-CD1 4.04Å; L400-F451 HydrophobicContact CD2-CE1 3.98Å; L400-F451 WeakPolarHBondContact O-CZ 3.36Å
401E94.7Very high94.7Very high76 Ų7633.2 Ų33.236%0.35518%0.177SC..Hα-helixtrans-71.1-26174.4-66.6-79.9-127.800112.3Y353 P397 Y398 R404 T405Y353-E401 PolarHBondContact OH-O 3.36Å; P397-E401 PolarHBondContact O-N 2.67Å; Y398-E401 PolarHBondContact O-N 2.65Å; E401-R404 IonicContact OE1-NH1 2.7Å; E401-R404 PolarHBondContact OE1-NH1 3.03Å; E401-R404 WeakPolarHBondContact OE2-CD 3.42Å; E401-R404 IonicContact OE2-CZ 3.91Å; E401-R404 IonicContact OE2-NE 3.69Å; E401-R404 IonicContact OE2-NH1 3.7Å; E401-R404 PolarHBondContact OE2-NH1 3.33Å; E401-T405 PolarHBondContact O-N 2.97Å; E401-T405 VanDerWaalsContact O-N 3.08Å; E401-T405 PolarHBondContact O-OG1 2.6Å
402A96.4Very high94.8Very high0 Ų039.7 Ų39.70%020%0.201CC..Hα-helixtrans-68.1-50.8168.700000111.6Y353 T387 Y398 Y399 L400 R404 T405 I406Y353-A402 HydrophobicContact CD1-CB 4.2Å; Y353-A402 HydrophobicContact CD2-CB 4.33Å; Y353-A402 HydrophobicContact CE1-CB 3.71Å; Y353-A402 HydrophobicContact CE2-CB 3.9Å; Y353-A402 HydrophobicContact CG-CB 4.48Å; Y353-A402 VanDerWaalsContact CZ-CA 3.42Å; Y353-A402 WeakPolarHBondContact OH-CA 3.4Å; Y353-A402 PolarHBondContact OH-N 2.88Å; T387-A402 HydrophobicContact CG2-CB 3.91Å; Y398-A402 PolarHBondContact O-N 3.15Å; Y398-A402 VanDerWaalsContact O-N 3.07Å; Y399-A402 WeakPolarHBondContact O-CB 3.47Å; Y399-A402 PolarHBondContact O-N 3.13Å; L400-A402 VanDerWaalsContact C-N 3.31Å; L400-A402 PolarHBondContact O-N 3.47Å; A402-R404 VanDerWaalsContact C-N 3.27Å; A402-R404 PolarHBondContact O-N 3.41Å; A402-T405 WeakPolarHBondContact O-CA 3.3Å; A402-T405 WeakPolarHBondContact O-CB 3.39Å; A402-T405 PolarHBondContact O-N 3.4Å; A402-I406 WeakPolarHBondContact O-CG1 3.36Å; A402-I406 PolarHBondContact O-N 3.11Å
403G97.5Very high95Very high0 Ų037.2 Ų37.20%019%0.191CC..Hα-helixtrans-57.4-38.4173.800000113.1Y399 L400 I406 L407Y399-G403 PolarHBondContact O-N 2.95Å; L400-G403 PolarHBondContact O-N 3.16Å; G403-I406 WeakPolarHBondContact O-CB 3.3Å; G403-I406 PolarHBondContact O-N 3.2Å; G403-L407 WeakPolarHBondContact O-CG 3.46Å; G403-L407 PolarHBondContact O-N 3.32Å
404R97.1Very high95.4Very high78 Ų7836.2 Ų36.229%0.29418%0.183SC..Hα-helixtrans-62.5-43173.8177.6-167.4-177.6163.17.9111.5M21 F29 L400 E401 A402 I406 L407 D408M21-R404 HydrophobicContact CE-CB 4.4Å; F29-R404 HydrophobicContact CE1-CG 3.82Å; F29-R404 HydrophobicContact CE2-CG 4.38Å; F29-R404 HydrophobicContact CZ-CG 3.73Å; L400-R404 WeakPolarHBondContact O-CB 3.24Å; L400-R404 PolarHBondContact O-N 2.98Å; E401-R404 IonicContact OE1-NH1 2.7Å; E401-R404 PolarHBondContact OE1-NH1 3.03Å; E401-R404 WeakPolarHBondContact OE2-CD 3.42Å; E401-R404 IonicContact OE2-CZ 3.91Å; E401-R404 IonicContact OE2-NE 3.69Å; E401-R404 IonicContact OE2-NH1 3.7Å; E401-R404 PolarHBondContact OE2-NH1 3.33Å; A402-R404 VanDerWaalsContact C-N 3.27Å; A402-R404 PolarHBondContact O-N 3.41Å; R404-I406 PolarHBondContact O-N 3.35Å; R404-L407 PolarHBondContact O-N 3.33Å; R404-D408 IonicContact NE-OD2 3.75Å; R404-D408 WeakPolarHBondContact O-CB 3.42Å; R404-D408 PolarHBondContact O-N 3Å
405T97.3Very high95.8Very high31 Ų3137.8 Ų37.819%0.1919%0.185CC..Hα-helixtrans-59.6-39175.8-560000110.7Y353 E401 A402 N409Y353-T405 HydrophobicContact CE2-CG2 4.26Å; Y353-T405 PolarHBondContact OH-OG1 2.69Å; E401-T405 PolarHBondContact O-N 2.97Å; E401-T405 VanDerWaalsContact O-N 3.08Å; E401-T405 PolarHBondContact O-OG1 2.6Å; A402-T405 WeakPolarHBondContact O-CA 3.3Å; A402-T405 WeakPolarHBondContact O-CB 3.39Å; A402-T405 PolarHBondContact O-N 3.4Å; T405-N409 VanDerWaalsContact O-CB 3.26Å; T405-N409 WeakPolarHBondContact O-CB 3.29Å; T405-N409 PolarHBondContact O-N 3.41Å; T405-N409 PolarHBondContact O-ND2 2.68Å
406I97.9Very high96.3Very high13 Ų1336.2 Ų36.27%0.06717%0.166CC..Hα-helixtrans-63.5-50.1173.7-58.1168.8000110.5F383 A384 A402 G403 R404 D408 N409 L410 M443 L447F383-I406 HydrophobicContact CD1-CD1 3.65Å; F383-I406 HydrophobicContact CD1-CG1 4.09Å; F383-I406 HydrophobicContact CE1-CD1 3.83Å; F383-I406 HydrophobicContact CE1-CG1 4.06Å; A384-I406 HydrophobicContact CB-CD1 4.11Å; A402-I406 WeakPolarHBondContact O-CG1 3.36Å; A402-I406 PolarHBondContact O-N 3.11Å; G403-I406 WeakPolarHBondContact O-CB 3.3Å; G403-I406 PolarHBondContact O-N 3.2Å; R404-I406 PolarHBondContact O-N 3.35Å; I406-D408 PolarHBondContact O-N 3.13Å; I406-N409 PolarHBondContact O-N 2.64Å; I406-L410 HydrophobicContact CG2-CD1 3.85Å; I406-L410 HydrophobicContact CG2-CG 4.3Å; I406-L410 WeakPolarHBondContact O-CB 3.33Å; I406-L410 WeakPolarHBondContact O-CG 3.34Å; I406-L410 PolarHBondContact O-N 3.32Å; I406-M443 HydrophobicContact CG2-CE 4.08Å; I406-M443 HydrophobicContact CG2-SD 4.31Å; I406-L447 HydrophobicContact CB-CD2 4.31Å; I406-L447 HydrophobicContact CD1-CD2 4.41Å; I406-L447 HydrophobicContact CG2-CD1 4.03Å; I406-L447 HydrophobicContact CG2-CD2 4.24Å
407L97.3Very high96.6Very high0 Ų040.2 Ų40.20%019%0.193CC..Hα-helixtrans-61.6-44.4179.6-70.7176.2000113.8F29 V33 M36 G403 R404 N409 N411 L447 F451F29-L407 HydrophobicContact CB-CD1 4.05Å; F29-L407 HydrophobicContact CD1-CD1 4.17Å; F29-L407 HydrophobicContact CG-CD1 4.47Å; V33-L407 HydrophobicContact CG2-CD1 4.06Å; V33-L407 HydrophobicContact CG2-CD2 3.87Å; M36-L407 HydrophobicContact CE-CD2 4.11Å; M36-L407 HydrophobicContact SD-CD2 3.58Å; M36-L407 VanDerWaalsContact SD-CD2 3.58Å; G403-L407 WeakPolarHBondContact O-CG 3.46Å; G403-L407 PolarHBondContact O-N 3.32Å; R404-L407 PolarHBondContact O-N 3.33Å; L407-N409 VanDerWaalsContact C-N 3.34Å; L407-N411 WeakPolarHBondContact O-CB 3.22Å; L407-N411 PolarHBondContact O-N 2.96Å; L407-N411 PolarHBondContact O-ND2 3.3Å; L407-L447 HydrophobicContact CD2-CB 4.44Å; L407-L447 HydrophobicContact CD2-CD1 3.86Å; L407-F451 HydrophobicContact CD1-CD2 3.86Å; L407-F451 HydrophobicContact CD1-CE2 3.39Å; L407-F451 HydrophobicContact CD1-CZ 4.14Å; L407-F451 HydrophobicContact CG-CE2 4.24Å
408D97.6Very high97Very high69 Ų6938.6 Ų38.637%0.36918%0.183SC..Hα-helixtrans-66-38.7178.8-78-23.1000110.2R404 I406 R412R404-D408 IonicContact NE-OD2 3.75Å; R404-D408 WeakPolarHBondContact O-CB 3.42Å; R404-D408 PolarHBondContact O-N 3Å; I406-D408 PolarHBondContact O-N 3.13Å; D408-R412 WeakPolarHBondContact O-CB 3.26Å; D408-R412 PolarHBondContact O-N 3.38Å
409N97.6Very high97.3Very high18 Ų1836.7 Ų36.710%0.09618%0.175CC..Hα-helixtrans-73.6-40.5177.9-70.3-11.6000112.8N360 F361 T405 I406 L407 R412 F413N360-N409 PolarHBondContact O-ND2 2.87Å; F361-N409 HydrophobicContact CE1-CB 4.36Å; F361-N409 HydrophobicContact CZ-CB 4.35Å; T405-N409 VanDerWaalsContact O-CB 3.26Å; T405-N409 WeakPolarHBondContact O-CB 3.29Å; T405-N409 PolarHBondContact O-N 3.41Å; T405-N409 PolarHBondContact O-ND2 2.68Å; I406-N409 PolarHBondContact O-N 2.64Å; L407-N409 VanDerWaalsContact C-N 3.34Å; N409-R412 PolarHBondContact O-N 3.06Å; N409-F413 HydrophobicContact CB-CD2 4.06Å; N409-F413 HydrophobicContact CB-CE2 4.44Å; N409-F413 WeakPolarHBondContact O-CB 3.42Å; N409-F413 WeakPolarHBondContact O-CD2 3.28Å; N409-F413 PolarHBondContact O-N 3.35Å
410L98.3Very high97.4Very high0 Ų036.7 Ų36.70%018%0.175CC..Iπ-helixtrans-58.2-49.7172.8-76.3171.6000111.3M36 F361 L379 I406 R412 A414 R415 F420 F439 M443 L447M36-L410 HydrophobicContact CE-CB 3.59Å; M36-L410 HydrophobicContact CE-CD1 4.03Å; M36-L410 HydrophobicContact CE-CG 4.47Å; F361-L410 HydrophobicContact CE1-CD2 4.12Å; L379-L410 HydrophobicContact CD2-CD2 4.17Å; I406-L410 HydrophobicContact CG2-CD1 3.85Å; I406-L410 HydrophobicContact CG2-CG 4.3Å; I406-L410 WeakPolarHBondContact O-CB 3.33Å; I406-L410 WeakPolarHBondContact O-CG 3.34Å; I406-L410 PolarHBondContact O-N 3.32Å; L410-R412 VanDerWaalsContact C-N 3.34Å; L410-R412 PolarHBondContact O-N 2.94Å; L410-A414 HydrophobicContact CD2-CB 4.18Å; L410-A414 PolarHBondContact O-N 2.94Å; L410-R415 PolarHBondContact O-N 2.8Å; L410-F420 HydrophobicContact CB-CE1 4.21Å; L410-F439 HydrophobicContact CD1-CE2 4.26Å; L410-F439 HydrophobicContact CD1-CZ 4.45Å; L410-F439 HydrophobicContact CD2-CE2 3.87Å; L410-F439 HydrophobicContact CD2-CZ 4.13Å; L410-M443 HydrophobicContact CD1-CE 4.35Å; L410-M443 HydrophobicContact CD1-SD 4.35Å; L410-L447 HydrophobicContact CD1-CD1 4.08Å
411N98Very high97.5Very high41 Ų4136.5 Ų36.522%0.21917%0.174CC..Iπ-helixtrans-65.6-34.3178-80.4-71.5000113.5Q32 M36 L407 R415Q32-N411 PolarHBondContact NE2-ND2 2.71Å; M36-N411 WeakPolarHBondContact CE-ND2 3.49Å; M36-N411 PolarHBondContact SD-ND2 3.38Å; L407-N411 WeakPolarHBondContact O-CB 3.22Å; L407-N411 PolarHBondContact O-N 2.96Å; L407-N411 PolarHBondContact O-ND2 3.3Å; N411-R415 WeakPolarHBondContact OD1-CD 3.23Å; N411-R415 PolarHBondContact OD1-NH1 3Å; N411-R415 VanDerWaalsContact OD1-NH1 3.14Å
412R97.2Very high97.6Very high184 Ų18433 Ų3369%0.69416%0.158SC*.Iπ-helixtrans-82.9-33.6-174.6-179.7175.5177.4-175.8-2.4113.9D408 N409 L410D408-R412 WeakPolarHBondContact O-CB 3.26Å; D408-R412 PolarHBondContact O-N 3.38Å; N409-R412 PolarHBondContact O-N 3.06Å; L410-R412 VanDerWaalsContact C-N 3.34Å; L410-R412 PolarHBondContact O-N 2.94Å
413F96.9Very high97.5Very high51 Ų5133.1 Ų33.122%0.22416%0.159CC..Iπ-helixtrans-120.4-36.8-169.1-59.8-69000113.7N360 F361 N409 H431N360-F413 HydrophobicContact CB-CD2 4.06Å; N360-F413 HydrophobicContact CB-CE2 3.72Å; N360-F413 HydrophobicContact CB-CZ 4.31Å; N360-F413 WeakPolarHBondContact OD1-CE2 3.17Å; N360-F413 WeakPolarHBondContact OD1-CZ 3.27Å; F361-F413 HydrophobicContact CE2-CB 3.6Å; F361-F413 HydrophobicContact CE2-CD2 4.24Å; F361-F413 HydrophobicContact CE2-CG 4.26Å; F361-F413 HydrophobicContact CZ-CB 3.9Å; N409-F413 HydrophobicContact CB-CD2 4.06Å; N409-F413 HydrophobicContact CB-CE2 4.44Å; N409-F413 WeakPolarHBondContact O-CB 3.42Å; N409-F413 WeakPolarHBondContact O-CD2 3.28Å; N409-F413 PolarHBondContact O-N 3.35Å; F413-H431 PolarHBondContact O-NE2 2.66Å
414A97.8Very high97.3Very high0 Ų038.9 Ų38.90%018%0.184CC..Iπ-helixtrans-95.5-27.2-17700000113.8F361 L379 L410 V416 F420 A421 M423F361-A414 HydrophobicContact CZ-CB 4.17Å; L379-A414 HydrophobicContact CD2-CB 3.74Å; L410-A414 HydrophobicContact CD2-CB 4.18Å; L410-A414 PolarHBondContact O-N 2.94Å; A414-V416 PolarHBondContact O-N 2.83Å; A414-F420 HydrophobicContact CB-CD1 4.16Å; A414-F420 CarbonylContact O-C 3.59Å; A414-F420 WeakPolarHBondContact O-CA 3.19Å; A414-A421 PolarHBondContact O-N 3Å; A414-M423 HydrophobicContact CB-SD 4.38Å
415R98.3Very high97.1Very high66 Ų6636.4 Ų36.425%0.24918%0.177CC..EExtended strand (participates in β ladder)trans-67.5128.9-177.4-165171.6-178.7168.9-2.8112.2E35 H39 L410 N411 F420E35-R415 IonicContact OE1-CZ 3.44Å; E35-R415 IonicContact OE1-NH1 3.29Å; E35-R415 PolarHBondContact OE1-NH1 3.13Å; E35-R415 IonicContact OE1-NH2 2.7Å; E35-R415 PolarHBondContact OE1-NH2 3.39Å; E35-R415 IonicContact OE2-CZ 3.61Å; E35-R415 IonicContact OE2-NH1 2.75Å; E35-R415 PolarHBondContact OE2-NH1 3.07Å; E35-R415 IonicContact OE2-NH2 3.6Å; H39-R415 PolarHBondContact ND1-NH2 2.92Å; L410-R415 PolarHBondContact O-N 2.8Å; N411-R415 WeakPolarHBondContact OD1-CD 3.23Å; N411-R415 PolarHBondContact OD1-NH1 3Å; N411-R415 VanDerWaalsContact OD1-NH1 3.14Å; R415-F420 HydrophobicContact CB-CD1 3.83Å; R415-F420 HydrophobicContact CB-CE1 3.51Å; R415-F420 HydrophobicContact CB-CZ 4.04Å; R415-F420 HydrophobicContact CG-CD1 4.27Å; R415-F420 HydrophobicContact CG-CE1 3.79Å; R415-F420 HydrophobicContact CG-CE2 4.24Å; R415-F420 HydrophobicContact CG-CZ 3.77Å
416V98.1Very high96.8Very high17 Ų1735.3 Ų35.310%0.10317%0.17CC..EExtended strand (participates in β ladder)trans-131.7169.2-179.9-65.50000109.7H39 P56 L57 A414 C418 G419 A421H39-V416 PolarHBondContact CE1-O 3.41Å; H39-V416 VanDerWaalsContact CE1-O 3.31Å; H39-V416 PolarHBondContact NE2-O 3.43Å; P56-V416 HydrophobicContact CB-CG2 3.7Å; P56-V416 HydrophobicContact CG-CG2 4.13Å; P56-V416 WeakPolarHBondContact O-CG2 3.38Å; L57-V416 HydrophobicContact CD2-CB 4.22Å; L57-V416 HydrophobicContact CD2-CG1 3.77Å; L57-V416 HydrophobicContact CD2-CG2 4.26Å; A414-V416 PolarHBondContact O-N 2.83Å; V416-C418 VanDerWaalsContact C-N 3.27Å; V416-C418 PolarHBondContact O-N 2.87Å; V416-G419 WeakPolarHBondContact CG2-O 3.35Å; V416-G419 PolarHBondContact N-O 3.28Å; V416-G419 PolarHBondContact O-N 3.35Å; V416-A421 HydrophobicContact CG1-CB 3.98Å; V416-A421 HydrophobicContact CG2-CB 4.02Å
417P98Very high96.4Very high111 Ų11142 Ų4272%0.72119%0.194SC*.THydrogen-bonded Turntrans-56.3-39.2-172.9-28.837.2000114.1H39H39-P417 PolarHBondContact CE1-O 2.96Å
418C97.3Very high96.1Very high11 Ų1146.7 Ų46.77%0.07422%0.223CC..THydrogen-bonded Turntrans-107.936-175.5-56.40000113.1N43 L54 P56 C59 V416N43-C418 WeakPolarHBondContact OD1-CA 3.32Å; L54-C418 VanDerWaalsContact CD2-O 3.27Å; L54-C418 WeakPolarHBondContact CD2-O 3.43Å; P56-C418 WeakPolarHBondContact CA-O 3.5Å; P56-C418 WeakPolarHBondContact CB-O 3.27Å; P56-C418 WeakPolarHBondContact O-CB 3.12Å; C59-C418 HydrophobicContact CB-CB 3.71Å; C59-C418 WeakPolarHBondContact CB-SG 3.04Å; C59-C418 WeakPolarHBondContact SG-CB 3.4Å; C59-C418 CovalentContact SG-SG 2.03Å; C59-C418 PolarHBondContact SG-SG 3.12Å; V416-C418 VanDerWaalsContact C-N 3.27Å; V416-C418 PolarHBondContact O-N 2.87Å
419G97.7Very high95.7Very high0 Ų045 Ų450%022%0.221CC..EExtended strand (participates in β ladder)trans132.7-141.6176.200000113.9H39 V416H39-G419 PolarHBondContact NE2-N 2.87Å; H39-G419 PolarHBondContact NE2-O 2.93Å; V416-G419 WeakPolarHBondContact CG2-O 3.35Å; V416-G419 PolarHBondContact N-O 3.28Å; V416-G419 PolarHBondContact O-N 3.35Å
420F98.5Very high95.5Very high0 Ų046.3 Ų46.30%023%0.232CC..EExtended strand (participates in β ladder)trans-127.5125.2173-71.5-103.8000109.3M36 H39 A40 P56 L379 L410 A414 R415 M435 F439 F444M36-F420 HydrophobicContact CB-CE2 4.17Å; M36-F420 HydrophobicContact CB-CZ 3.82Å; M36-F420 HydrophobicContact CE-CE1 3.68Å; M36-F420 HydrophobicContact CE-CZ 3.68Å; M36-F420 HydrophobicContact CG-CZ 3.92Å; H39-F420 AromaticContact CD2-CE2 3.63Å; A40-F420 HydrophobicContact CB-CD2 3.99Å; A40-F420 HydrophobicContact CB-CE2 4.26Å; P56-F420 WeakPolarHBondContact CG-O 3.18Å; L379-F420 HydrophobicContact CD1-CB 3.89Å; L410-F420 HydrophobicContact CB-CE1 4.21Å; A414-F420 HydrophobicContact CB-CD1 4.16Å; A414-F420 CarbonylContact O-C 3.59Å; A414-F420 WeakPolarHBondContact O-CA 3.19Å; R415-F420 HydrophobicContact CB-CD1 3.83Å; R415-F420 HydrophobicContact CB-CE1 3.51Å; R415-F420 HydrophobicContact CB-CZ 4.04Å; R415-F420 HydrophobicContact CG-CD1 4.27Å; R415-F420 HydrophobicContact CG-CE1 3.79Å; R415-F420 HydrophobicContact CG-CE2 4.24Å; R415-F420 HydrophobicContact CG-CZ 3.77Å; F420-M435 HydrophobicContact CB-SD 4.38Å; F420-M435 WeakPolarHBondContact O-CB 3.28Å; F420-M435 VanDerWaalsContact O-CG 3.28Å; F420-M435 WeakPolarHBondContact O-CG 3.49Å; F420-F439 HydrophobicContact CB-CD1 4.27Å; F420-F439 HydrophobicContact CB-CE1 3.52Å; F420-F439 HydrophobicContact CB-CZ 3.9Å; F420-F439 HydrophobicContact CD1-CE1 4.28Å; F420-F439 HydrophobicContact CD1-CZ 4.02Å; F420-F439 AromaticContact CD2-CE1 3.63Å; F420-F439 HydrophobicContact CD2-CE1 3.63Å; F420-F439 HydrophobicContact CD2-CZ 4.14Å; F420-F439 HydrophobicContact CE2-CE1 4.41Å; F420-F439 AromaticContact CG-CE1 3.56Å; F420-F439 HydrophobicContact CG-CE1 3.56Å; F420-F439 AromaticContact CG-CZ 3.77Å; F420-F439 HydrophobicContact CG-CZ 3.77Å; F420-F444 HydrophobicContact CD2-CZ 4.41Å; F420-F444 HydrophobicContact CE2-CZ 4.05Å; F420-F444 HydrophobicContact CZ-CZ 4.39Å
421A97.9Very high95.4Very high0 Ų049.5 Ų49.50%025%0.247CC..PPolyproline II helixtrans-93.9134.9-178.800000111.2P56 L57 A414 V416 H431P56-A421 HydrophobicContact CG-CB 3.89Å; L57-A421 HydrophobicContact CD2-CB 3.73Å; L57-A421 HydrophobicContact CG-CB 4.16Å; A414-A421 PolarHBondContact O-N 3Å; V416-A421 HydrophobicContact CG1-CB 3.98Å; V416-A421 HydrophobicContact CG2-CB 4.02Å; A421-H431 HydrophobicContact CB-CB 4.01Å
422A96.5Very high95.1Very high2 Ų250 Ų502%0.01725%0.248CC..PPolyproline II helixtrans-52.4148.9167.500000112P378 H431 E432 R434P378-A422 HydrophobicContact CB-CB 4.4Å; A422-H431 CarbonylContact O-C 3.57Å; A422-H431 WeakPolarHBondContact O-CA 3.48Å; A422-E432 HydrophobicContact CB-CB 4.17Å; A422-E432 PolarHBondContact O-N 3.15Å; A422-R434 HydrophobicContact CB-CB 4.1Å; A422-R434 HydrophobicContact CB-CG 4.26Å; A422-R434 PolarHBondContact N-O 2.95Å
423M95.7Very high95.1Very high3 Ų343.2 Ų43.22%0.01523%0.226CC..EExtended strand (participates in β ladder)trans-89.5120.7175.3-53.2-55.7-56.300109.5F361 Q376 H377 A414 V426F361-M423 HydrophobicContact CD2-CG 3.83Å; F361-M423 HydrophobicContact CE2-CG 3.69Å; F361-M423 HydrophobicContact CE2-SD 3.94Å; F361-M423 HydrophobicContact CZ-CG 4.27Å; F361-M423 HydrophobicContact CZ-SD 4.43Å; Q376-M423 CarbonylContact C-O 3.54Å; Q376-M423 WeakPolarHBondContact CA-O 3.22Å; H377-M423 HydrophobicContact CB-CB 4.19Å; H377-M423 PolarHBondContact N-O 3.22Å; H377-M423 PolarHBondContact O-N 3.15Å; A414-M423 HydrophobicContact CB-SD 4.38Å; M423-V426 HydrophobicContact CB-CG1 4.08Å
424K92.6Very high95Very high122 Ų12242.2 Ų42.253%0.5322%0.22SC..EExtended strand (participates in β ladder)trans-74.9-34.9173.3-176165.7-177163.60112.3S430 H431 E432K424-S430 PolarHBondContact N-O 3.29Å; K424-H431 WeakPolarHBondContact CB-O 3.45Å; K424-E432 HydrophobicContact CB-CB 4.18Å
425D91.8Very high94.9Very high26 Ų2642.3 Ų42.314%0.13922%0.221CC..EExtended strand (participates in β ladder)trans-150.8106.9174.7-173.5-29.2000110.7A375 R427 T428 G429 S430A375-D425 HydrophobicContact CB-CB 4.04Å; A375-D425 VanDerWaalsContact CB-CG 3.49Å; A375-D425 WeakPolarHBondContact CB-OD1 3.12Å; A375-D425 CarbonylContact O-C 3.3Å; A375-D425 VanDerWaalsContact O-CA 3.27Å; A375-D425 WeakPolarHBondContact O-CA 3.44Å; D425-R427 PolarHBondContact O-N 2.05Å; D425-R427 VanDerWaalsContact O-N 3.13Å; D425-R427 WeakPolarHBondContact OD1-CA 3.48Å; D425-R427 WeakPolarHBondContact OD1-CB 3.22Å; D425-R427 VanDerWaalsContact OD1-CG 3.3Å; D425-R427 WeakPolarHBondContact OD1-CG 3.2Å; D425-R427 IonicContact OD1-CZ 3.96Å; D425-R427 PolarHBondContact OD1-N 2.56Å; D425-R427 IonicContact OD1-NE 2.9Å; D425-R427 PolarHBondContact OD1-NE 3.12Å; D425-R427 IonicContact OD1-NH2 2.84Å; D425-R427 IonicContact OD2-CZ 3.17Å; D425-R427 IonicContact OD2-NE 3.45Å; D425-R427 PolarHBondContact OD2-NE 3.47Å; D425-R427 IonicContact OD2-NH2 4Å; D425-R427 PolarHBondContact OD2-NH2 2.9Å; D425-T428 HydrophobicContact CB-CG2 4.31Å; D425-T428 WeakPolarHBondContact CB-OG1 3.36Å; D425-T428 PolarHBondContact O-N 3.18Å; D425-T428 VanDerWaalsContact O-N 3.14Å; D425-T428 PolarHBondContact O-OG1 3.31Å; D425-T428 VanDerWaalsContact O-OG1 3.13Å; D425-G429 PolarHBondContact O-N 3.47Å; D425-S430 PolarHBondContact N-O 3.15Å
426V92.4Very high94.8Very high7 Ų739.3 Ų39.34%0.04221%0.209CC..THydrogen-bonded Turntrans-61.2-18.5-179.8-61.60000114H359 F361 P363 V372 A375 H377 M423H359-V426 HydrophobicContact CB-CG2 4.17Å; F361-V426 HydrophobicContact CB-CG1 3.86Å; F361-V426 HydrophobicContact CD2-CG1 4.27Å; F361-V426 HydrophobicContact CG-CG1 4.49Å; P363-V426 HydrophobicContact CB-CG2 4.11Å; V372-V426 HydrophobicContact CG2-CG2 4.16Å; A375-V426 WeakPolarHBondContact O-CG1 3.41Å; A375-V426 PolarHBondContact O-N 2.91Å; H377-V426 HydrophobicContact CB-CG1 3.75Å; M423-V426 HydrophobicContact CB-CG1 4.08Å
427R88.2Confident94.8Very high154 Ų15438.5 Ų38.558%0.58121%0.205SC*.THydrogen-bonded Turntrans-81.5-29.7179-48.5167.3-71.3-159.64.5111.8V372 D425V372-R427 HydrophobicContact CB-CG 4.33Å; V372-R427 HydrophobicContact CG1-CG 4.42Å; V372-R427 HydrophobicContact CG2-CG 3.87Å; D425-R427 PolarHBondContact O-N 2.05Å; D425-R427 VanDerWaalsContact O-N 3.13Å; D425-R427 WeakPolarHBondContact OD1-CA 3.48Å; D425-R427 WeakPolarHBondContact OD1-CB 3.22Å; D425-R427 VanDerWaalsContact OD1-CG 3.3Å; D425-R427 WeakPolarHBondContact OD1-CG 3.2Å; D425-R427 IonicContact OD1-CZ 3.96Å; D425-R427 PolarHBondContact OD1-N 2.56Å; D425-R427 IonicContact OD1-NE 2.9Å; D425-R427 PolarHBondContact OD1-NE 3.12Å; D425-R427 IonicContact OD1-NH2 2.84Å; D425-R427 IonicContact OD2-CZ 3.17Å; D425-R427 IonicContact OD2-NE 3.45Å; D425-R427 PolarHBondContact OD2-NE 3.47Å; D425-R427 IonicContact OD2-NH2 4Å; D425-R427 PolarHBondContact OD2-NH2 2.9Å
428T91.6Very high94.8Very high98 Ų9833.6 Ų33.660%0.60117%0.172SC*.THydrogen-bonded Turntrans-100.3-24.9-179.467.80000112.4D425 S430D425-T428 HydrophobicContact CB-CG2 4.31Å; D425-T428 WeakPolarHBondContact CB-OG1 3.36Å; D425-T428 PolarHBondContact O-N 3.18Å; D425-T428 VanDerWaalsContact O-N 3.14Å; D425-T428 PolarHBondContact O-OG1 3.31Å; D425-T428 VanDerWaalsContact O-OG1 3.13Å; T428-S430 VanDerWaalsContact C-N 3.35Å; T428-S430 WeakPolarHBondContact OG1-CB 3.48Å; T428-S430 PolarHBondContact OG1-N 2.8Å; T428-S430 VanDerWaalsContact OG1-N 3.12Å; T428-S430 PolarHBondContact OG1-OG 2.65Å
429G89.6Confident94.8Very high33 Ų3333 Ų3334%0.3417%0.168SC..THydrogen-bonded Turntrans78.615.6-170.700000113.8D425D425-G429 PolarHBondContact O-N 3.47Å
430S92.9Very high94.9Very high47 Ų4733 Ų3333%0.32917%0.168SC..EExtended strand (participates in β ladder)trans-75.7139.8177.161.20000112.3K424 D425 T428K424-S430 PolarHBondContact N-O 3.29Å; D425-S430 PolarHBondContact N-O 3.15Å; T428-S430 VanDerWaalsContact C-N 3.35Å; T428-S430 WeakPolarHBondContact OG1-CB 3.48Å; T428-S430 PolarHBondContact OG1-N 2.8Å; T428-S430 VanDerWaalsContact OG1-N 3.12Å; T428-S430 PolarHBondContact OG1-OG 2.65Å
431H96.3Very high94.8Very high66 Ų6633 Ų3331%0.30617%0.168SC..EExtended strand (participates in β ladder)trans-87.5159.4178.7-59.3109.6000114.3L57 F413 A421 A422 K424L57-H431 HydrophobicContact CD1-CB 3.74Å; L57-H431 HydrophobicContact CD2-CB 4.15Å; F413-H431 PolarHBondContact O-NE2 2.66Å; A421-H431 HydrophobicContact CB-CB 4.01Å; A422-H431 CarbonylContact O-C 3.57Å; A422-H431 WeakPolarHBondContact O-CA 3.48Å; K424-H431 WeakPolarHBondContact CB-O 3.45Å
432E93Very high94.9Very high53 Ų5333.7 Ų33.725%0.24817%0.172CC..  trans-111.3144160-173.7172.1129.600108.3A422 K424 R434A422-E432 HydrophobicContact CB-CB 4.17Å; A422-E432 PolarHBondContact O-N 3.15Å; K424-E432 HydrophobicContact CB-CB 4.18Å; E432-R434 HydrophobicContact CG-CB 4.1Å; E432-R434 PolarHBondContact O-N 2.72Å; E432-R434 WeakPolarHBondContact OE1-CD 3.28Å; E432-R434 IonicContact OE1-NH1 2.67Å; E432-R434 PolarHBondContact OE1-NH1 3.19Å
433D95.6Very high94.9Very high41 Ų4133.9 Ų33.922%0.21917%0.172CC..SBendtrans-81.170.4-178-163.211.8000110.9M55 P56 L57 T58M55-D433 WeakPolarHBondContact CA-OD1 3.45Å; M55-D433 WeakPolarHBondContact CB-OD1 3.38Å; M55-D433 WeakPolarHBondContact CG-O 3.32Å; P56-D433 WeakPolarHBondContact CD-OD1 3.29Å; P56-D433 VanDerWaalsContact N-OD1 3.11Å; L57-D433 WeakPolarHBondContact CA-OD1 3.47Å; L57-D433 HydrophobicContact CB-CB 4.19Å; L57-D433 VanDerWaalsContact CB-OD1 3.26Å; L57-D433 WeakPolarHBondContact CB-OD1 3.34Å; L57-D433 HydrophobicContact CD1-CB 3.92Å; L57-D433 HydrophobicContact CG-CB 4.18Å; L57-D433 PolarHBondContact N-OD1 3.14Å; T58-D433 VanDerWaalsContact CB-OD2 3.29Å; T58-D433 WeakPolarHBondContact CB-OD2 3.27Å; T58-D433 WeakPolarHBondContact CG2-OD2 3.5Å; T58-D433 PolarHBondContact N-OD1 2.9Å; T58-D433 PolarHBondContact N-OD2 2.66Å; T58-D433 PolarHBondContact OG1-OD2 3.13Å
434R94.4Very high95.1Very high30 Ų3033.8 Ų33.811%0.11317%0.171CC..  trans-152.8133.6-168171.2177.4-177.7170.60.4111.2A422 E432 D436A422-R434 HydrophobicContact CB-CB 4.1Å; A422-R434 HydrophobicContact CB-CG 4.26Å; A422-R434 PolarHBondContact N-O 2.95Å; E432-R434 HydrophobicContact CG-CB 4.1Å; E432-R434 PolarHBondContact O-N 2.72Å; E432-R434 WeakPolarHBondContact OE1-CD 3.28Å; E432-R434 IonicContact OE1-NH1 2.67Å; E432-R434 PolarHBondContact OE1-NH1 3.19Å; R434-D436 WeakPolarHBondContact CD-OD2 3.32Å; R434-D436 WeakPolarHBondContact CG-OD2 3.31Å; R434-D436 IonicContact CZ-OD1 2.75Å; R434-D436 IonicContact CZ-OD2 2.69Å; R434-D436 VanDerWaalsContact NE-CG 3.32Å; R434-D436 IonicContact NE-OD1 3.18Å; R434-D436 PolarHBondContact NE-OD1 3.24Å; R434-D436 VanDerWaalsContact NE-OD1 3.12Å; R434-D436 IonicContact NE-OD2 2.75Å; R434-D436 PolarHBondContact NE-OD2 2.99Å; R434-D436 IonicContact NH2-OD1 3.49Å; R434-D436 PolarHBondContact NH2-OD1 3.18Å; R434-D436 IonicContact NH2-OD2 2.6Å
435M97.4Very high95.3Very high1 Ų128 Ų281%0.00515%0.146CC..BIsolated β-bridgetrans-138.4100.3165.5-166.2-178.98800108.6A40 L54 P56 L379 F420 F439 L440A40-M435 HydrophobicContact CB-CE 4.24Å; A40-M435 HydrophobicContact CB-SD 4.18Å; L54-M435 HydrophobicContact CB-CB 4.38Å; L54-M435 HydrophobicContact CB-CE 4.16Å; L54-M435 HydrophobicContact CD2-CE 3.66Å; L54-M435 HydrophobicContact CD2-SD 4.11Å; L54-M435 PolarHBondContact O-N 3.32Å; P56-M435 HydrophobicContact CG-CB 4.2Å; L379-M435 HydrophobicContact CD1-CG 4.5Å; F420-M435 HydrophobicContact CB-SD 4.38Å; F420-M435 WeakPolarHBondContact O-CB 3.28Å; F420-M435 VanDerWaalsContact O-CG 3.28Å; F420-M435 WeakPolarHBondContact O-CG 3.49Å; M435-F439 HydrophobicContact CG-CB 4.48Å; M435-F439 HydrophobicContact CG-CD1 3.97Å; M435-F439 HydrophobicContact SD-CD1 4.06Å; M435-L440 HydrophobicContact CE-CD1 4.46Å; M435-L440 HydrophobicContact CE-CG 4.43Å
436D96.2Very high95.6Very high3 Ų326.8 Ų26.82%0.01614%0.14CC..  trans-66.9155.6179-56.7-120.1000112.1R434 F438 F439R434-D436 WeakPolarHBondContact CD-OD2 3.32Å; R434-D436 WeakPolarHBondContact CG-OD2 3.31Å; R434-D436 IonicContact CZ-OD1 2.75Å; R434-D436 IonicContact CZ-OD2 2.69Å; R434-D436 VanDerWaalsContact NE-CG 3.32Å; R434-D436 IonicContact NE-OD1 3.18Å; R434-D436 PolarHBondContact NE-OD1 3.24Å; R434-D436 VanDerWaalsContact NE-OD1 3.12Å; R434-D436 IonicContact NE-OD2 2.75Å; R434-D436 PolarHBondContact NE-OD2 2.99Å; R434-D436 IonicContact NH2-OD1 3.49Å; R434-D436 PolarHBondContact NH2-OD1 3.18Å; R434-D436 IonicContact NH2-OD2 2.6Å; D436-F438 HydrophobicContact CB-CD1 3.73Å; D436-F438 HydrophobicContact CB-CD2 4.37Å; D436-F438 HydrophobicContact CB-CE1 3.3Å; D436-F438 HydrophobicContact CB-CE2 4Å; D436-F438 HydrophobicContact CB-CG 4.23Å; D436-F438 HydrophobicContact CB-CZ 3.44Å; D436-F438 VanDerWaalsContact CB-CZ 3.44Å; D436-F438 PolarHBondContact O-N 2.97Å; D436-F438 WeakPolarHBondContact OD1-CE1 3.41Å; D436-F439 WeakPolarHBondContact O-CB 3.2Å; D436-F439 PolarHBondContact O-N 2.82Å
437S97.5Very high95.9Very high0 Ų026.4 Ų26.40%014%0.138CC..THydrogen-bonded Turntrans-63.3-39.4-175.766.70000113.9T83 D86 R127 F439 L440 A441T83-S437 WeakPolarHBondContact OG1-CB 3.46Å; D86-S437 WeakPolarHBondContact OD2-CB 3.28Å; D86-S437 PolarHBondContact OD2-OG 3.12Å; R127-S437 WeakPolarHBondContact CD-OG 3.31Å; R127-S437 PolarHBondContact NH1-OG 3.39Å; S437-F439 PolarHBondContact O-N 3.14Å; S437-L440 PolarHBondContact O-N 3.46Å; S437-A441 PolarHBondContact O-N 3.19Å
438F97.7Very high96.4Very high8 Ų819.5 Ų19.54%0.03511%0.112CC..Hα-helixtrans-57.4-21.917658.6-109.4000113.7D86 P378 P381 D436 L440 A441 E442 M443 E469D86-F438 PolarHBondContact OD2-N 3.36Å; P378-F438 WeakPolarHBondContact O-CE2 3.09Å; P378-F438 WeakPolarHBondContact O-CZ 3.36Å; P381-F438 HydrophobicContact CG-CD2 4.19Å; D436-F438 HydrophobicContact CB-CD1 3.73Å; D436-F438 HydrophobicContact CB-CD2 4.37Å; D436-F438 HydrophobicContact CB-CE1 3.3Å; D436-F438 HydrophobicContact CB-CE2 4Å; D436-F438 HydrophobicContact CB-CG 4.23Å; D436-F438 HydrophobicContact CB-CZ 3.44Å; D436-F438 VanDerWaalsContact CB-CZ 3.44Å; D436-F438 PolarHBondContact O-N 2.97Å; D436-F438 WeakPolarHBondContact OD1-CE1 3.41Å; F438-L440 PolarHBondContact O-N 2.84Å; F438-A441 PolarHBondContact O-N 3.13Å; F438-E442 HydrophobicContact CB-CG 4.22Å; F438-E442 WeakPolarHBondContact O-CB 3.48Å; F438-E442 PolarHBondContact O-N 3.48Å; F438-M443 PolarHBondContact O-N 3Å; F438-E469 WeakPolarHBondContact CB-OE1 3.36Å
439F98.3Very high96.7Very high0 Ų015.3 Ų15.30%09%0.086CC..Iπ-helixtrans-64.2-29.8176.1-174-111.5000112.2A40 L379 L410 F420 M435 D436 S437 M443 F444A40-F439 HydrophobicContact CB-CE1 4.49Å; L379-F439 HydrophobicContact CB-CD2 3.41Å; L379-F439 VanDerWaalsContact CB-CD2 3.41Å; L379-F439 HydrophobicContact CB-CE2 3.84Å; L379-F439 HydrophobicContact CB-CG 4.1Å; L379-F439 HydrophobicContact CD1-CB 4.47Å; L379-F439 HydrophobicContact CD1-CD1 4.01Å; L379-F439 HydrophobicContact CD1-CD2 3.74Å; L379-F439 HydrophobicContact CD1-CE1 4.18Å; L379-F439 HydrophobicContact CD1-CE2 3.92Å; L379-F439 HydrophobicContact CD1-CG 3.78Å; L379-F439 HydrophobicContact CD1-CZ 4.14Å; L379-F439 HydrophobicContact CG-CD2 4.17Å; L379-F439 HydrophobicContact CG-CE2 4.37Å; L410-F439 HydrophobicContact CD1-CE2 4.26Å; L410-F439 HydrophobicContact CD1-CZ 4.45Å; L410-F439 HydrophobicContact CD2-CE2 3.87Å; L410-F439 HydrophobicContact CD2-CZ 4.13Å; F420-F439 HydrophobicContact CB-CD1 4.27Å; F420-F439 HydrophobicContact CB-CE1 3.52Å; F420-F439 HydrophobicContact CB-CZ 3.9Å; F420-F439 HydrophobicContact CD1-CE1 4.28Å; F420-F439 HydrophobicContact CD1-CZ 4.02Å; F420-F439 AromaticContact CD2-CE1 3.63Å; F420-F439 HydrophobicContact CD2-CE1 3.63Å; F420-F439 HydrophobicContact CD2-CZ 4.14Å; F420-F439 HydrophobicContact CE2-CE1 4.41Å; F420-F439 AromaticContact CG-CE1 3.56Å; F420-F439 HydrophobicContact CG-CE1 3.56Å; F420-F439 AromaticContact CG-CZ 3.77Å; F420-F439 HydrophobicContact CG-CZ 3.77Å; M435-F439 HydrophobicContact CG-CB 4.48Å; M435-F439 HydrophobicContact CG-CD1 3.97Å; M435-F439 HydrophobicContact SD-CD1 4.06Å; D436-F439 WeakPolarHBondContact O-CB 3.2Å; D436-F439 PolarHBondContact O-N 2.82Å; S437-F439 PolarHBondContact O-N 3.14Å; F439-M443 HydrophobicContact CD2-CB 3.68Å; F439-M443 HydrophobicContact CD2-CG 3.7Å; F439-M443 HydrophobicContact CE2-CB 3.9Å; F439-M443 HydrophobicContact CE2-CG 3.85Å; F439-M443 WeakPolarHBondContact O-CB 3.48Å; F439-F444 AromaticContact CD1-CE2 3.87Å; F439-F444 HydrophobicContact CD1-CE2 3.87Å; F439-F444 HydrophobicContact CD1-CZ 4.39Å; F439-F444 HydrophobicContact CE1-CD2 4.44Å; F439-F444 AromaticContact CE1-CE2 3.36Å; F439-F444 HydrophobicContact CE1-CE2 3.36Å; F439-F444 AromaticContact CE1-CZ 3.45Å; F439-F444 HydrophobicContact CE1-CZ 3.45Å; F439-F444 VanDerWaalsContact CE1-CZ 3.45Å; F439-F444 HydrophobicContact CE2-CZ 4.46Å; F439-F444 HydrophobicContact CZ-CE1 4.26Å; F439-F444 AromaticContact CZ-CE2 3.79Å; F439-F444 HydrophobicContact CZ-CE2 3.79Å; F439-F444 AromaticContact CZ-CZ 3.49Å; F439-F444 HydrophobicContact CZ-CZ 3.49Å; F439-F444 VanDerWaalsContact CZ-CZ 3.49Å; F439-F444 VanDerWaalsContact O-CD2 3.3Å; F439-F444 WeakPolarHBondContact O-CD2 3.25Å
440L98.3Very high97.1Very high0 Ų013.8 Ų13.80%07%0.07CC..Iπ-helixtrans-86.1-42.1170.9-67.4-173.8000112.5F37 A40 Y41 T83 T87 M435 S437 F438 F444F37-L440 HydrophobicContact CD2-CD2 4.11Å; F37-L440 HydrophobicContact CE2-CB 4.43Å; F37-L440 HydrophobicContact CE2-CD2 4.19Å; A40-L440 HydrophobicContact CB-CD2 3.53Å; Y41-L440 HydrophobicContact CD2-CD1 4.12Å; T83-L440 HydrophobicContact CG2-CD1 3.6Å; T83-L440 HydrophobicContact CG2-CG 4.44Å; T87-L440 HydrophobicContact CG2-CB 3.98Å; T87-L440 HydrophobicContact CG2-CD1 4.3Å; T87-L440 VanDerWaalsContact OG1-CB 3.23Å; T87-L440 WeakPolarHBondContact OG1-CB 3.26Å; M435-L440 HydrophobicContact CE-CD1 4.46Å; M435-L440 HydrophobicContact CE-CG 4.43Å; S437-L440 PolarHBondContact O-N 3.46Å; F438-L440 PolarHBondContact O-N 2.84Å; L440-F444 HydrophobicContact CD2-CD2 3.88Å; L440-F444 HydrophobicContact CD2-CE2 3.89Å
441A97.7Very high97.3Very high0 Ų011.5 Ų11.50%05%0.054CC..Iπ-helixtrans-74-30.5-174.500000114.6D86 T90 S437 F438 K445D86-A441 HydrophobicContact CB-CB 4.27Å; D86-A441 VanDerWaalsContact CG-CB 3.48Å; D86-A441 WeakPolarHBondContact O-CB 3.41Å; D86-A441 WeakPolarHBondContact OD1-CB 3.35Å; T90-A441 PolarHBondContact OG1-O 3.23Å; S437-A441 PolarHBondContact O-N 3.19Å; F438-A441 PolarHBondContact O-N 3.13Å; A441-K445 VanDerWaalsContact O-CB 3.31Å; A441-K445 WeakPolarHBondContact O-CB 3.34Å; A441-K445 VanDerWaalsContact O-CD 3.28Å; A441-K445 WeakPolarHBondContact O-CD 3.46Å; A441-K445 WeakPolarHBondContact O-CE 3.4Å; A441-K445 PolarHBondContact O-NZ 3.17Å
442E98.6Very high97.2Very high14 Ų148.7 Ų8.77%0.0654%0.042CC..Iπ-helixtrans-115.6-58.4-173.7-60.6-160.6-108.700113.4P381 F438 F444 K445 Y446 A470P381-E442 HydrophobicContact CB-CB 3.56Å; P381-E442 HydrophobicContact CB-CG 4.45Å; P381-E442 HydrophobicContact CG-CB 3.83Å; P381-E442 VanDerWaalsContact CG-CD 3.43Å; P381-E442 HydrophobicContact CG-CG 4.22Å; P381-E442 WeakPolarHBondContact CG-OE1 3.49Å; F438-E442 HydrophobicContact CB-CG 4.22Å; F438-E442 WeakPolarHBondContact O-CB 3.48Å; F438-E442 PolarHBondContact O-N 3.48Å; E442-F444 PolarHBondContact O-N 3.41Å; E442-K445 WeakPolarHBondContact O-CA 3.38Å; E442-K445 WeakPolarHBondContact O-CB 3.49Å; E442-K445 PolarHBondContact O-N 3.39Å; E442-Y446 HydrophobicContact CB-CD2 4.23Å; E442-Y446 HydrophobicContact CB-CE2 3.99Å; E442-Y446 HydrophobicContact CG-CE2 4.49Å; E442-Y446 VanDerWaalsContact O-CD2 3.24Å; E442-Y446 WeakPolarHBondContact O-CD2 3.42Å; E442-Y446 PolarHBondContact O-N 3.4Å; E442-Y446 WeakPolarHBondContact OE2-CE2 3.43Å; E442-A470 HydrophobicContact CB-CB 4.23Å; E442-A470 HydrophobicContact CG-CB 3.74Å
443M98.3Very high97.2Very high6 Ų68.4 Ų8.43%0.034%0.041CC..Iπ-helixtrans-56.6-50.2-168.5-112-62.4-161.700111.6L379 R380 P381 A384 I406 L410 F438 F439 L447L379-M443 WeakPolarHBondContact O-CG 3.47Å; R380-M443 WeakPolarHBondContact O-CE 3.48Å; P381-M443 HydrophobicContact CB-CB 4.49Å; P381-M443 HydrophobicContact CB-CG 3.95Å; A384-M443 HydrophobicContact CB-SD 3.86Å; I406-M443 HydrophobicContact CG2-CE 4.08Å; I406-M443 HydrophobicContact CG2-SD 4.31Å; L410-M443 HydrophobicContact CD1-CE 4.35Å; L410-M443 HydrophobicContact CD1-SD 4.35Å; F438-M443 PolarHBondContact O-N 3Å; F439-M443 HydrophobicContact CD2-CB 3.68Å; F439-M443 HydrophobicContact CD2-CG 3.7Å; F439-M443 HydrophobicContact CE2-CB 3.9Å; F439-M443 HydrophobicContact CE2-CG 3.85Å; F439-M443 WeakPolarHBondContact O-CB 3.48Å; M443-L447 WeakPolarHBondContact O-CB 3.48Å; M443-L447 WeakPolarHBondContact O-CD1 3.29Å; M443-L447 WeakPolarHBondContact O-CG 3.45Å; M443-L447 PolarHBondContact O-N 3.38Å; M443-L447 VanDerWaalsContact O-N 3.13Å; M443-L447 HydrophobicContact SD-CD1 3.92Å
444F98.3Very high96.9Very high0 Ų010.7 Ų10.70%07%0.065CC..Hα-helixtrans-73.7-27.9177.1-65.8-55.1000113.4V33 M36 F37 A40 F420 F439 L440 E442 F448V33-F444 HydrophobicContact CG1-CB 4.21Å; V33-F444 HydrophobicContact CG1-CD1 3.97Å; M36-F444 HydrophobicContact CB-CD1 4.32Å; M36-F444 HydrophobicContact CB-CE1 3.39Å; M36-F444 HydrophobicContact CB-CZ 3.75Å; M36-F444 HydrophobicContact CE-CE1 3.91Å; M36-F444 HydrophobicContact CE-CZ 4.49Å; M36-F444 HydrophobicContact CG-CE1 4.44Å; M36-F444 HydrophobicContact SD-CE1 4.31Å; F37-F444 HydrophobicContact CB-CB 4.27Å; F37-F444 HydrophobicContact CB-CD1 4.44Å; F37-F444 HydrophobicContact CB-CD2 4.04Å; F37-F444 HydrophobicContact CB-CG 4Å; F37-F444 HydrophobicContact CD2-CB 3.9Å; F37-F444 AromaticContact CD2-CD2 3.84Å; F37-F444 HydrophobicContact CD2-CD2 3.84Å; F37-F444 HydrophobicContact CD2-CG 4.13Å; F37-F444 HydrophobicContact CG-CD2 4.42Å; A40-F444 HydrophobicContact CB-CE2 3.91Å; A40-F444 HydrophobicContact CB-CZ 4.44Å; F420-F444 HydrophobicContact CD2-CZ 4.41Å; F420-F444 HydrophobicContact CE2-CZ 4.05Å; F420-F444 HydrophobicContact CZ-CZ 4.39Å; F439-F444 AromaticContact CD1-CE2 3.87Å; F439-F444 HydrophobicContact CD1-CE2 3.87Å; F439-F444 HydrophobicContact CD1-CZ 4.39Å; F439-F444 HydrophobicContact CE1-CD2 4.44Å; F439-F444 AromaticContact CE1-CE2 3.36Å; F439-F444 HydrophobicContact CE1-CE2 3.36Å; F439-F444 AromaticContact CE1-CZ 3.45Å; F439-F444 HydrophobicContact CE1-CZ 3.45Å; F439-F444 VanDerWaalsContact CE1-CZ 3.45Å; F439-F444 HydrophobicContact CE2-CZ 4.46Å; F439-F444 HydrophobicContact CZ-CE1 4.26Å; F439-F444 AromaticContact CZ-CE2 3.79Å; F439-F444 HydrophobicContact CZ-CE2 3.79Å; F439-F444 AromaticContact CZ-CZ 3.49Å; F439-F444 HydrophobicContact CZ-CZ 3.49Å; F439-F444 VanDerWaalsContact CZ-CZ 3.49Å; F439-F444 VanDerWaalsContact O-CD2 3.3Å; F439-F444 WeakPolarHBondContact O-CD2 3.25Å; L440-F444 HydrophobicContact CD2-CD2 3.88Å; L440-F444 HydrophobicContact CD2-CE2 3.89Å; E442-F444 PolarHBondContact O-N 3.41Å; F444-F448 WeakPolarHBondContact O-CB 3.46Å; F444-F448 PolarHBondContact O-N 2.98Å
445K97.9Very high96.7Very high0 Ų015.8 Ų15.80%09%0.09CC..Hα-helixtrans-63.1-54.5175.7-172.3-179.4-77.2160.60110.5D89 T90 L93 A441 E442 F448 L449 F466 A470D89-K445 VanDerWaalsContact CG-NZ 3.3Å; D89-K445 WeakPolarHBondContact OD1-CE 3.48Å; D89-K445 IonicContact OD1-NZ 3.55Å; D89-K445 PolarHBondContact OD1-NZ 3.5Å; D89-K445 IonicContact OD2-NZ 3.69Å; D89-K445 PolarHBondContact OD2-NZ 3.09Å; D89-K445 VanDerWaalsContact OD2-NZ 3.12Å; T90-K445 HydrophobicContact CG2-CB 4.42Å; T90-K445 WeakPolarHBondContact OG1-CE 3.31Å; T90-K445 PolarHBondContact OG1-NZ 3.42Å; L93-K445 HydrophobicContact CD2-CG 3.62Å; A441-K445 VanDerWaalsContact O-CB 3.31Å; A441-K445 WeakPolarHBondContact O-CB 3.34Å; A441-K445 VanDerWaalsContact O-CD 3.28Å; A441-K445 WeakPolarHBondContact O-CD 3.46Å; A441-K445 WeakPolarHBondContact O-CE 3.4Å; A441-K445 PolarHBondContact O-NZ 3.17Å; E442-K445 WeakPolarHBondContact O-CA 3.38Å; E442-K445 WeakPolarHBondContact O-CB 3.49Å; E442-K445 PolarHBondContact O-N 3.39Å; K445-F448 PolarHBondContact O-N 3.06Å; K445-L449 HydrophobicContact CG-CD1 4.4Å; K445-L449 VanDerWaalsContact O-CG 3.27Å; K445-L449 WeakPolarHBondContact O-CG 3.49Å; K445-L449 PolarHBondContact O-N 2.93Å; K445-L449 VanDerWaalsContact O-N 3.12Å; K445-F466 HydrophobicContact CD-CD1 4.35Å; K445-F466 HydrophobicContact CD-CE1 4.05Å; K445-F466 HydrophobicContact CG-CE1 4.39Å; K445-A470 HydrophobicContact CD-CB 3.77Å; K445-A470 WeakPolarHBondContact CD-O 3.37Å; K445-A470 WeakPolarHBondContact CE-O 3.46Å; K445-A470 PolarHBondContact NZ-O 3.08Å
446Y98.5Very high96.4Very high1 Ų117.6 Ų17.60%0.00410%0.1CC..Hα-helixtrans-66.4-40.9177.9-63.3-56.3000113.1E385 Y388 E442 F448 L449 L450 F466 A470E385-Y446 HydrophobicContact CB-CD1 4.32Å; E385-Y446 HydrophobicContact CB-CD2 3.82Å; E385-Y446 HydrophobicContact CB-CE1 4.15Å; E385-Y446 HydrophobicContact CB-CE2 3.6Å; E385-Y446 HydrophobicContact CB-CG 4.17Å; E385-Y446 HydrophobicContact CG-CD1 4.33Å; E385-Y446 HydrophobicContact CG-CD2 4.48Å; E385-Y446 HydrophobicContact CG-CE1 3.78Å; E385-Y446 HydrophobicContact CG-CE2 3.94Å; Y388-Y446 AromaticContact CD1-CD1 3.97Å; Y388-Y446 HydrophobicContact CD1-CD1 3.97Å; Y388-Y446 HydrophobicContact CG-CD1 4.46Å; E442-Y446 HydrophobicContact CB-CD2 4.23Å; E442-Y446 HydrophobicContact CB-CE2 3.99Å; E442-Y446 HydrophobicContact CG-CE2 4.49Å; E442-Y446 VanDerWaalsContact O-CD2 3.24Å; E442-Y446 WeakPolarHBondContact O-CD2 3.42Å; E442-Y446 PolarHBondContact O-N 3.4Å; E442-Y446 WeakPolarHBondContact OE2-CE2 3.43Å; Y446-F448 PolarHBondContact O-N 3.01Å; Y446-L449 PolarHBondContact O-N 2.9Å; Y446-L450 WeakPolarHBondContact O-CB 3.42Å; Y446-L450 PolarHBondContact O-N 3.37Å; Y446-F466 HydrophobicContact CE1-CD1 4.14Å; Y446-F466 HydrophobicContact CE1-CE1 4.3Å; Y446-A470 HydrophobicContact CE1-CB 4.27Å; Y446-A470 HydrophobicContact CE2-CB 3.77Å; Y446-A470 VanDerWaalsContact CZ-CB 3.48Å; Y446-A470 WeakPolarHBondContact OH-CB 3.4Å
447L98.4Very high96.2Very high0 Ų019.4 Ų19.40%011%0.109CC..Hα-helixtrans-67.2-34.5177.6-69.3169.4000112.1V33 A384 I406 L407 L410 M443 L450 F451V33-L447 HydrophobicContact CG1-CB 4.26Å; V33-L447 HydrophobicContact CG2-CB 4.04Å; A384-L447 HydrophobicContact CB-CD2 4.3Å; A384-L447 HydrophobicContact CB-CG 4.27Å; I406-L447 HydrophobicContact CB-CD2 4.31Å; I406-L447 HydrophobicContact CD1-CD2 4.41Å; I406-L447 HydrophobicContact CG2-CD1 4.03Å; I406-L447 HydrophobicContact CG2-CD2 4.24Å; L407-L447 HydrophobicContact CD2-CB 4.44Å; L407-L447 HydrophobicContact CD2-CD1 3.86Å; L410-L447 HydrophobicContact CD1-CD1 4.08Å; M443-L447 WeakPolarHBondContact O-CB 3.48Å; M443-L447 WeakPolarHBondContact O-CD1 3.29Å; M443-L447 WeakPolarHBondContact O-CG 3.45Å; M443-L447 PolarHBondContact O-N 3.38Å; M443-L447 VanDerWaalsContact O-N 3.13Å; M443-L447 HydrophobicContact SD-CD1 3.92Å; L447-L450 HydrophobicContact CD2-CD2 4.46Å; L447-F451 WeakPolarHBondContact O-CD2 3.43Å; L447-F451 PolarHBondContact O-N 3.47Å
448F98.4Very high95.8Very high8 Ų822 Ų224%0.03513%0.127CC..Hα-helixtrans-64.8-50.1173.6178.4-102000111R30 V33 V34 L93 L94 F444 K445 Y446 L450 F451 A452R30-F448 HydrophobicContact CG-CD2 3.78Å; R30-F448 HydrophobicContact CG-CE2 3.65Å; V33-F448 HydrophobicContact CG1-CB 3.98Å; V34-F448 HydrophobicContact CG2-CD2 4.06Å; V34-F448 HydrophobicContact CG2-CE2 3.99Å; L93-F448 HydrophobicContact CD2-CD1 4.31Å; L93-F448 HydrophobicContact CG-CD1 4.14Å; L93-F448 HydrophobicContact CG-CE1 4.28Å; L94-F448 HydrophobicContact CD2-CB 3.71Å; L94-F448 HydrophobicContact CD2-CD1 3.82Å; L94-F448 HydrophobicContact CD2-CD2 3.38Å; L94-F448 HydrophobicContact CD2-CE1 4.25Å; L94-F448 HydrophobicContact CD2-CE2 3.85Å; L94-F448 HydrophobicContact CD2-CG 3.36Å; L94-F448 HydrophobicContact CD2-CZ 4.26Å; F444-F448 WeakPolarHBondContact O-CB 3.46Å; F444-F448 PolarHBondContact O-N 2.98Å; K445-F448 PolarHBondContact O-N 3.06Å; Y446-F448 PolarHBondContact O-N 3.01Å; F448-L450 PolarHBondContact O-N 3.48Å; F448-F451 PolarHBondContact O-N 2.92Å; F448-F451 VanDerWaalsContact O-N 3.1Å; F448-A452 HydrophobicContact CE1-CB 4.34Å; F448-A452 WeakPolarHBondContact O-CB 3.48Å; F448-A452 PolarHBondContact O-N 3.09Å
449L97.6Very high95.5Very high11 Ų1123 Ų236%0.05813%0.131CC..Hα-helixtrans-61.3-30.6179.9-68.5167.7000113.4L93 Y388 K445 Y446 I457 V461 F466L93-L449 HydrophobicContact CD1-CD2 4Å; L93-L449 HydrophobicContact CD2-CD1 4.12Å; L93-L449 HydrophobicContact CD2-CD2 4.01Å; L93-L449 HydrophobicContact CD2-CG 3.94Å; Y388-L449 HydrophobicContact CD2-CB 3.71Å; Y388-L449 HydrophobicContact CE1-CD1 4.2Å; Y388-L449 HydrophobicContact CE2-CB 3.41Å; Y388-L449 VanDerWaalsContact CE2-CB 3.41Å; Y388-L449 HydrophobicContact CE2-CD1 4.49Å; Y388-L449 HydrophobicContact CE2-CG 4.46Å; Y388-L449 HydrophobicContact CG-CB 4.38Å; K445-L449 HydrophobicContact CG-CD1 4.4Å; K445-L449 VanDerWaalsContact O-CG 3.27Å; K445-L449 WeakPolarHBondContact O-CG 3.49Å; K445-L449 PolarHBondContact O-N 2.93Å; K445-L449 VanDerWaalsContact O-N 3.12Å; Y446-L449 PolarHBondContact O-N 2.9Å; L449-I457 HydrophobicContact CD2-CD1 4.1Å; L449-V461 HydrophobicContact CD2-CG2 3.96Å; L449-F466 HydrophobicContact CD1-CE1 3.91Å; L449-F466 HydrophobicContact CD1-CZ 3.63Å
450L97.3Very high95.3Very high0 Ų027.5 Ų27.50%016%0.155CC..Hα-helixtrans-68-35.3175179.361000113T387 Y391 L400 Y446 L447 F448T387-L450 HydrophobicContact CG2-CD1 4.48Å; T387-L450 HydrophobicContact CG2-CD2 3.79Å; Y391-L450 HydrophobicContact CD1-CD1 3.64Å; Y391-L450 HydrophobicContact CG-CD1 3.64Å; L400-L450 HydrophobicContact CD2-CD1 3.9Å; L400-L450 HydrophobicContact CD2-CG 4.14Å; L400-L450 VanDerWaalsContact CD2-O 3.23Å; L400-L450 WeakPolarHBondContact CD2-O 3.22Å; Y446-L450 WeakPolarHBondContact O-CB 3.42Å; Y446-L450 PolarHBondContact O-N 3.37Å; L447-L450 HydrophobicContact CD2-CD2 4.46Å; F448-L450 PolarHBondContact O-N 3.48Å
451F97.3Very high95Very high0 Ų027.9 Ų27.90%016%0.157CC..Hα-helixtrans-103.9-13.6-176.2-67.3-63.2000115.2M21 K26 F29 R30 V33 L400 L407 L447 F448M21-F451 HydrophobicContact CE-CE1 4.06Å; M21-F451 HydrophobicContact SD-CD1 4.09Å; M21-F451 HydrophobicContact SD-CE1 3.78Å; K26-F451 VanDerWaalsContact CE-O 3.24Å; K26-F451 WeakPolarHBondContact CE-O 3.4Å; K26-F451 HydrophobicContact CG-CD1 4.48Å; F29-F451 HydrophobicContact CB-CB 4.4Å; F29-F451 HydrophobicContact CB-CD1 3.79Å; F29-F451 HydrophobicContact CB-CD2 4.02Å; F29-F451 HydrophobicContact CB-CE1 4.05Å; F29-F451 HydrophobicContact CB-CE2 4.28Å; F29-F451 HydrophobicContact CB-CG 3.79Å; F29-F451 HydrophobicContact CB-CZ 4.3Å; F29-F451 HydrophobicContact CD2-CE1 4.35Å; F29-F451 HydrophobicContact CG-CE1 4.4Å; R30-F451 HydrophobicContact CB-CB 3.85Å; V33-F451 HydrophobicContact CG2-CD2 4.25Å; L400-F451 HydrophobicContact CB-CE1 4.15Å; L400-F451 HydrophobicContact CD2-CD1 4.04Å; L400-F451 HydrophobicContact CD2-CE1 3.98Å; L400-F451 WeakPolarHBondContact O-CZ 3.36Å; L407-F451 HydrophobicContact CD1-CD2 3.86Å; L407-F451 HydrophobicContact CD1-CE2 3.39Å; L407-F451 HydrophobicContact CD1-CZ 4.14Å; L407-F451 HydrophobicContact CG-CE2 4.24Å; L447-F451 WeakPolarHBondContact O-CD2 3.43Å; L447-F451 PolarHBondContact O-N 3.47Å; F448-F451 PolarHBondContact O-N 2.92Å; F448-F451 VanDerWaalsContact O-N 3.1Å
452A95.1Very high94.7Very high7 Ų732.5 Ų32.56%0.05818%0.179CC..  trans-62.4155.6173.300000112.5K26 F448 D456 I457K26-A452 PolarHBondContact NZ-O 2.9Å; F448-A452 HydrophobicContact CE1-CB 4.34Å; F448-A452 WeakPolarHBondContact O-CB 3.48Å; F448-A452 PolarHBondContact O-N 3.09Å; A452-D456 HydrophobicContact CB-CB 4.24Å; A452-I457 HydrophobicContact CB-CD1 4.19Å; A452-I457 HydrophobicContact CB-CG1 3.94Å
453E92.1Very high94.5Very high47 Ų4736.8 Ų36.822%0.2220%0.202CC..  trans-100.5164.7155.5-56.7-59.5165.600110.2R23 K26 E455 D456R23-E453 HydrophobicContact CG-CG 4.25Å; K26-E453 WeakPolarHBondContact CD-OE1 3.46Å; K26-E453 VanDerWaalsContact CE-OE1 3.29Å; K26-E453 WeakPolarHBondContact CE-OE1 3.28Å; K26-E453 IonicContact NZ-OE1 3.49Å; K26-E453 PolarHBondContact NZ-OE1 2.88Å; K26-E453 IonicContact NZ-OE2 2.83Å; K26-E453 PolarHBondContact NZ-OE2 2.83Å; E453-E455 VanDerWaalsContact CB-OE2 3.23Å; E453-E455 WeakPolarHBondContact CB-OE2 3.46Å; E453-E455 PolarHBondContact O-N 2.77Å; E453-E455 VanDerWaalsContact O-N 3.1Å; E453-D456 PolarHBondContact N-OD2 2.88Å; E453-D456 WeakPolarHBondContact O-CB 3.47Å; E453-D456 PolarHBondContact O-N 3.04Å
454A89.2Confident94.4Very high89 Ų8938 Ų3874%0.73621%0.207SC*.THydrogen-bonded Turntrans-60.3-22.2-178.800000113.8D456A454-D456 VanDerWaalsContact C-N 3.35Å
455E90.1Very high94.3Very high136 Ų13638.5 Ų38.564%0.63621%0.209SC*.THydrogen-bonded Turntrans-84.2-6.1175.3-43.498.7135.800114R23 E453R23-E455 IonicContact CZ-OE1 3.51Å; R23-E455 IonicContact CZ-OE2 2.67Å; R23-E455 IonicContact NH1-OE1 2.78Å; R23-E455 IonicContact NH2-OE1 2.67Å; R23-E455 PolarHBondContact NH2-OE1 2.95Å; R23-E455 IonicContact NH2-OE2 3.56Å; R23-E455 PolarHBondContact NH2-OE2 2.86Å; E453-E455 VanDerWaalsContact CB-OE2 3.23Å; E453-E455 WeakPolarHBondContact CB-OE2 3.46Å; E453-E455 PolarHBondContact O-N 2.77Å; E453-E455 VanDerWaalsContact O-N 3.1Å
456D90.9Very high94.3Very high40 Ų4039.1 Ų39.121%0.21421%0.212CC..THydrogen-bonded Turntrans-93-17.2178-60.5-45.4000113.2R30 A452 E453 A454R30-D456 WeakPolarHBondContact CD-OD2 3.49Å; R30-D456 IonicContact CZ-OD1 2.78Å; R30-D456 IonicContact CZ-OD2 3.56Å; R30-D456 IonicContact NE-OD2 2.66Å; R30-D456 IonicContact NH1-OD1 2.68Å; R30-D456 PolarHBondContact NH1-OD1 3.37Å; R30-D456 IonicContact NH1-OD2 3.64Å; R30-D456 PolarHBondContact NH1-OD2 3.3Å; A452-D456 HydrophobicContact CB-CB 4.24Å; E453-D456 PolarHBondContact N-OD2 2.88Å; E453-D456 WeakPolarHBondContact O-CB 3.47Å; E453-D456 PolarHBondContact O-N 3.04Å; A454-D456 VanDerWaalsContact C-N 3.35Å
457I92.3Very high94.3Very high40 Ų4039 Ų3921%0.20521%0.212CC..SBendtrans-93.9129-173.8-50.1178.2000108.8L93 L449 A452 F459 V461L93-I457 HydrophobicContact CD1-CG2 3.83Å; L449-I457 HydrophobicContact CD2-CD1 4.1Å; A452-I457 HydrophobicContact CB-CD1 4.19Å; A452-I457 HydrophobicContact CB-CG1 3.94Å; I457-F459 VanDerWaalsContact C-N 3.3Å; I457-F459 VanDerWaalsContact CG2-O 3.25Å; I457-F459 WeakPolarHBondContact CG2-O 3.35Å; I457-F459 PolarHBondContact O-N 3.35Å; I457-V461 HydrophobicContact CG2-CG2 3.8Å
458P89.9Confident94.3Very high56 Ų5640.4 Ų40.436%0.36422%0.22SC..SBendtrans-76.5-8.8-171.124.1-28.5000115.6V92 L93 N95V92-P458 VanDerWaalsContact O-CG 3.29Å; V92-P458 WeakPolarHBondContact O-CG 3.39Å; L93-P458 WeakPolarHBondContact O-CD 3.47Å; N95-P458 HydrophobicContact CB-CG 4.45Å
459F91.9Very high94.3Very high27 Ų2740.5 Ų40.512%0.11822%0.221CC..SBendtrans-151.8166.1178.354-90.4000109.9V92 L93 M138 M141 I457 V461 Y464 L472V92-F459 HydrophobicContact CG1-CE1 4.27Å; L93-F459 HydrophobicContact CB-CZ 4.36Å; L93-F459 HydrophobicContact CD1-CE1 4.12Å; L93-F459 HydrophobicContact CD1-CE2 4.34Å; L93-F459 HydrophobicContact CD1-CZ 3.67Å; M138-F459 HydrophobicContact CE-CE1 4.4Å; M138-F459 HydrophobicContact CE-CE2 4.19Å; M138-F459 HydrophobicContact CE-CZ 4.02Å; M138-F459 HydrophobicContact SD-CD1 4.37Å; M138-F459 HydrophobicContact SD-CE1 3.65Å; M138-F459 HydrophobicContact SD-CE2 4.42Å; M138-F459 HydrophobicContact SD-CZ 3.68Å; M141-F459 HydrophobicContact CE-CB 4.39Å; M141-F459 HydrophobicContact CE-CD1 3.65Å; M141-F459 HydrophobicContact CE-CE1 4.26Å; M141-F459 HydrophobicContact CE-CG 4.23Å; M141-F459 HydrophobicContact SD-CB 3.5Å; M141-F459 WeakPolarHBondContact SD-CB 3.3Å; M141-F459 HydrophobicContact SD-CD1 3.61Å; M141-F459 HydrophobicContact SD-CD2 4.3Å; M141-F459 HydrophobicContact SD-CE1 4.42Å; M141-F459 HydrophobicContact SD-CG 3.55Å; M141-F459 VanDerWaalsContact SD-CG 3.55Å; I457-F459 VanDerWaalsContact C-N 3.3Å; I457-F459 VanDerWaalsContact CG2-O 3.25Å; I457-F459 WeakPolarHBondContact CG2-O 3.35Å; I457-F459 PolarHBondContact O-N 3.35Å; F459-V461 HydrophobicContact CD2-CG2 4.26Å; F459-V461 HydrophobicContact CE2-CG2 3.84Å; F459-V461 PolarHBondContact O-N 3.02Å; F459-Y464 HydrophobicContact CD2-CD2 4.05Å; F459-Y464 AromaticContact CD2-CE2 3.62Å; F459-Y464 HydrophobicContact CD2-CE2 3.62Å; F459-Y464 HydrophobicContact CE2-CD2 4.11Å; F459-Y464 AromaticContact CE2-CE2 3.99Å; F459-Y464 HydrophobicContact CE2-CE2 3.99Å; F459-L472 HydrophobicContact CE2-CD1 3.86Å; F459-L472 HydrophobicContact CZ-CD1 3.55Å
460D92.3Very high94.3Very high96 Ų9640 Ų4051%0.51322%0.218SC..  trans-76.8120.7172.2-155.7-29.4000109.9E462 D463 Y464D460-E462 VanDerWaalsContact C-N 3.27Å; D460-E462 WeakPolarHBondContact OD1-CG 3.2Å; D460-E462 PolarHBondContact OD1-N 2.92Å; D460-D463 PolarHBondContact O-N 3.09Å; D460-Y464 WeakPolarHBondContact O-CD2 3.37Å
461V92.9Very high94.4Very high7 Ų740 Ų404%0.04222%0.218CC..G310 helixtrans-75.4-21.1-179.2169.50000111L93 L449 I457 F459 D463 Y464 F466L93-V461 HydrophobicContact CD1-CG2 4.03Å; L449-V461 HydrophobicContact CD2-CG2 3.96Å; I457-V461 HydrophobicContact CG2-CG2 3.8Å; F459-V461 HydrophobicContact CD2-CG2 4.26Å; F459-V461 HydrophobicContact CE2-CG2 3.84Å; F459-V461 PolarHBondContact O-N 3.02Å; V461-D463 PolarHBondContact O-N 3.36Å; V461-Y464 PolarHBondContact O-N 3.41Å; V461-F466 HydrophobicContact CG1-CE2 3.65Å; V461-F466 HydrophobicContact CG1-CZ 3.55Å
462E91.4Very high94.4Very high98 Ų9840 Ų4046%0.45822%0.218SC..G310 helixtrans-72.7-12.8177.3-46.3-62.7100.100112.9K392 D460 Y464 L475K392-E462 VanDerWaalsContact CE-OE1 3.32Å; K392-E462 WeakPolarHBondContact CE-OE1 3.45Å; K392-E462 WeakPolarHBondContact CE-OE2 3.23Å; K392-E462 IonicContact NZ-OE1 2.77Å; K392-E462 PolarHBondContact NZ-OE1 3.19Å; K392-E462 IonicContact NZ-OE2 2.76Å; K392-E462 PolarHBondContact NZ-OE2 3.41Å; K392-E462 VanDerWaalsContact NZ-OE2 3.16Å; D460-E462 VanDerWaalsContact C-N 3.27Å; D460-E462 WeakPolarHBondContact OD1-CG 3.2Å; D460-E462 PolarHBondContact OD1-N 2.92Å; E462-Y464 PolarHBondContact O-N 2.88Å; E462-L475 VanDerWaalsContact O-CD1 3.28Å; E462-L475 WeakPolarHBondContact O-CD1 3.32Å
463D93.7Very high94.5Very high104 Ų10439.6 Ų39.656%0.55622%0.215SC*.G310 helixtrans-76.4-0.3171.1-77.1-29.3000112.8D460 V461 L475D460-D463 PolarHBondContact O-N 3.09Å; V461-D463 PolarHBondContact O-N 3.36Å; D463-L475 WeakPolarHBondContact O-CB 3.24Å; D463-L475 WeakPolarHBondContact O-CG 3.47Å; D463-L475 PolarHBondContact O-N 3Å
464Y96.3Very high94.7Very high31 Ų3138.1 Ų38.112%0.12221%0.209CC..EExtended strand (participates in β ladder)trans-129155.2-175.2-62.4-97.8000112.4M138 M141 F459 D460 V461 E462 L472 L473 P474M138-Y464 HydrophobicContact CE-CD1 4.05Å; M138-Y464 HydrophobicContact CE-CE1 3.34Å; M138-Y464 HydrophobicContact CE-CE2 4.27Å; M138-Y464 VanDerWaalsContact CE-CZ 3.48Å; M141-Y464 PolarHBondContact SD-OH 2.95Å; M141-Y464 VanDerWaalsContact SD-OH 3.41Å; F459-Y464 HydrophobicContact CD2-CD2 4.05Å; F459-Y464 AromaticContact CD2-CE2 3.62Å; F459-Y464 HydrophobicContact CD2-CE2 3.62Å; F459-Y464 HydrophobicContact CE2-CD2 4.11Å; F459-Y464 AromaticContact CE2-CE2 3.99Å; F459-Y464 HydrophobicContact CE2-CE2 3.99Å; D460-Y464 WeakPolarHBondContact O-CD2 3.37Å; V461-Y464 PolarHBondContact O-N 3.41Å; E462-Y464 PolarHBondContact O-N 2.88Å; Y464-L472 HydrophobicContact CD1-CB 3.92Å; Y464-L472 HydrophobicContact CG-CB 4.32Å; Y464-L472 HydrophobicContact CG-CD2 4.44Å; Y464-L473 CarbonylContact C-O 3.59Å; Y464-L473 WeakPolarHBondContact CA-O 3.27Å; Y464-P474 HydrophobicContact CD1-CB 3.89Å; Y464-P474 HydrophobicContact CE1-CB 3.71Å; Y464-P474 HydrophobicContact CE1-CG 4.34Å
465V96.6Very high94.9Very high10 Ų1036.2 Ų36.26%0.06119%0.187CC..EExtended strand (participates in β ladder)trans-107.9139.2162.170.80000109.4K278 I281 L282 L473 L475K278-V465 HydrophobicContact CB-CG2 4.12Å; K278-V465 HydrophobicContact CD-CG2 4.32Å; K278-V465 HydrophobicContact CG-CG2 4.02Å; I281-V465 HydrophobicContact CG2-CB 4.5Å; I281-V465 HydrophobicContact CG2-CG2 4.32Å; L282-V465 HydrophobicContact CB-CG1 4.19Å; L282-V465 HydrophobicContact CD1-CG1 3.95Å; L282-V465 HydrophobicContact CD2-CG1 4.34Å; L282-V465 HydrophobicContact CG-CG1 4.38Å; V465-L473 HydrophobicContact CG1-CB 4.04Å; V465-L473 PolarHBondContact N-O 3.35Å; V465-L473 PolarHBondContact O-N 3.27Å; V465-L475 HydrophobicContact CB-CD2 4Å; V465-L475 HydrophobicContact CG1-CD2 4.42Å
466F97.9Very high94.9Very high13 Ų1333.3 Ų33.36%0.05718%0.181CC..EExtended strand (participates in β ladder)trans-79.9134.2171.1-65.8-98.2000109.5K278 F389 K445 Y446 L449 V461 A470 H471 L472K278-F466 WeakPolarHBondContact CD-O 3.37Å; K278-F466 WeakPolarHBondContact CE-O 3.44Å; K278-F466 PolarHBondContact NZ-O 3.34Å; F389-F466 HydrophobicContact CZ-CD2 4.37Å; K445-F466 HydrophobicContact CD-CD1 4.35Å; K445-F466 HydrophobicContact CD-CE1 4.05Å; K445-F466 HydrophobicContact CG-CE1 4.39Å; Y446-F466 HydrophobicContact CE1-CD1 4.14Å; Y446-F466 HydrophobicContact CE1-CE1 4.3Å; L449-F466 HydrophobicContact CD1-CE1 3.91Å; L449-F466 HydrophobicContact CD1-CZ 3.63Å; V461-F466 HydrophobicContact CG1-CE2 3.65Å; V461-F466 HydrophobicContact CG1-CZ 3.55Å; F466-A470 HydrophobicContact CD1-CB 4.15Å; F466-A470 WeakPolarHBondContact CD1-O 3.48Å; F466-H471 CarbonylContact C-O 3.52Å; F466-H471 VanDerWaalsContact CA-O 3.3Å; F466-H471 WeakPolarHBondContact CA-O 3.4Å; F466-L472 HydrophobicContact CD1-CD2 3.96Å; F466-L472 HydrophobicContact CD2-CD2 4.5Å; F466-L472 HydrophobicContact CE1-CD2 3.68Å; F466-L472 HydrophobicContact CE2-CD2 4.24Å; F466-L472 HydrophobicContact CG-CD2 4.36Å; F466-L472 HydrophobicContact CZ-CD2 3.83Å
467T98.4Very high94.8Very high0 Ų031.8 Ų31.80%017%0.173CC..  trans-66.9-172164.463.50000111.3L211 E212 Y275 K278 A470 H471 L473L211-T467 HydrophobicContact CB-CG2 4.49Å; L211-T467 HydrophobicContact CD1-CG2 4.39Å; E212-T467 WeakPolarHBondContact OE1-CG2 3.45Å; Y275-T467 WeakPolarHBondContact OH-CB 3.44Å; K278-T467 PolarHBondContact NZ-O 3.1Å; T467-A470 PolarHBondContact O-N 3.25Å; T467-H471 HydrophobicContact CG2-CB 4.07Å; T467-H471 PolarHBondContact N-O 3.5Å; T467-H471 WeakPolarHBondContact OG1-CB 3.23Å; T467-H471 PolarHBondContact OG1-N 3.05Å; T467-L473 HydrophobicContact CG2-CD1 3.61Å; T467-L473 HydrophobicContact CG2-CG 3.98Å
468T98.1Very high94.4Very high28 Ų2832.6 Ų32.617%0.17218%0.182CC..THydrogen-bonded Turntrans-66.7-46.4171.8-157.10000109.9I126 T208 E274 Y275 A470I126-T468 HydrophobicContact CB-CG2 3.99Å; I126-T468 HydrophobicContact CD1-CG2 4.09Å; I126-T468 HydrophobicContact CG2-CG2 3.8Å; T208-T468 HydrophobicContact CG2-CG2 3.92Å; E274-T468 VanDerWaalsContact OE1-CA 3.28Å; E274-T468 WeakPolarHBondContact OE1-CA 3.26Å; E274-T468 PolarHBondContact OE1-N 3.17Å; E274-T468 VanDerWaalsContact OE2-CB 3.27Å; E274-T468 WeakPolarHBondContact OE2-CB 3.17Å; E274-T468 PolarHBondContact OE2-OG1 3.04Å; Y275-T468 HydrophobicContact CE1-CG2 4.31Å; Y275-T468 PolarHBondContact OH-N 3.49Å; T468-A470 PolarHBondContact O-N 3.13Å
469E98.4Very high93.8Very high10 Ų1035.5 Ų35.55%0.04720%0.199CC..THydrogen-bonded Turntrans-72.925.1171.3-141.184.9178.800113.8I126 R127 F438 H471I126-E469 HydrophobicContact CB-CB 4.45Å; I126-E469 VanDerWaalsContact CD1-OE2 3.23Å; I126-E469 WeakPolarHBondContact CD1-OE2 3.37Å; I126-E469 WeakPolarHBondContact CG1-OE2 3.38Å; R127-E469 HydrophobicContact CB-CG 4.45Å; R127-E469 WeakPolarHBondContact CD-OE1 3.46Å; R127-E469 VanDerWaalsContact CG-CD 3.5Å; R127-E469 HydrophobicContact CG-CG 3.93Å; R127-E469 VanDerWaalsContact CG-OE1 3.29Å; R127-E469 WeakPolarHBondContact CG-OE1 3.15Å; R127-E469 IonicContact CZ-OE1 2.68Å; R127-E469 IonicContact NE-OE1 2.66Å; R127-E469 PolarHBondContact NE-OE1 3.48Å; F438-E469 WeakPolarHBondContact CB-OE1 3.36Å; E469-H471 PolarHBondContact O-N 3.3Å
470A98.1Very high92.7Very high0 Ų035.3 Ų35.30%020%0.203CC..  trans5519.7179.600000117E442 K445 Y446 F466 T467 T468E442-A470 HydrophobicContact CB-CB 4.23Å; E442-A470 HydrophobicContact CG-CB 3.74Å; K445-A470 HydrophobicContact CD-CB 3.77Å; K445-A470 WeakPolarHBondContact CD-O 3.37Å; K445-A470 WeakPolarHBondContact CE-O 3.46Å; K445-A470 PolarHBondContact NZ-O 3.08Å; Y446-A470 HydrophobicContact CE1-CB 4.27Å; Y446-A470 HydrophobicContact CE2-CB 3.77Å; Y446-A470 VanDerWaalsContact CZ-CB 3.48Å; Y446-A470 WeakPolarHBondContact OH-CB 3.4Å; F466-A470 HydrophobicContact CD1-CB 4.15Å; F466-A470 WeakPolarHBondContact CD1-O 3.48Å; T467-A470 PolarHBondContact O-N 3.25Å; T468-A470 PolarHBondContact O-N 3.13Å
471H98.5Very high91Very high0 Ų036.6 Ų36.60%022%0.216CC..  trans-75.1141.2179.7-61.6-56000112.9D86 D89 I126 R127 G131 F466 T467 E469 L473D86-H471 PolarHBondContact O-CE1 2.83Å; D86-H471 IonicContact OD1-CE1 3.73Å; D86-H471 PolarHBondContact OD1-CE1 3.36Å; D86-H471 IonicContact OD1-NE2 2.69Å; D86-H471 PolarHBondContact OD1-NE2 3.24Å; D89-H471 IonicContact OD1-ND1 3.18Å; D89-H471 VanDerWaalsContact OD2-CA 3.28Å; D89-H471 WeakPolarHBondContact OD2-CA 3.3Å; D89-H471 IonicContact OD2-ND1 3.81Å; I126-H471 PolarHBondContact O-CD2 3.03Å; I126-H471 PolarHBondContact O-NE2 3.14Å; R127-H471 PolarHBondContact O-NE2 3.33Å; G131-H471 VanDerWaalsContact CA-CE1 3.48Å; G131-H471 WeakPolarHBondContact CA-CE1 3.29Å; G131-H471 PolarHBondContact N-CD2 3.26Å; G131-H471 VanDerWaalsContact N-CD2 3.3Å; G131-H471 PolarHBondContact N-NE2 2.94Å; G131-H471 VanDerWaalsContact N-NE2 3.17Å; F466-H471 CarbonylContact C-O 3.52Å; F466-H471 VanDerWaalsContact CA-O 3.3Å; F466-H471 WeakPolarHBondContact CA-O 3.4Å; T467-H471 HydrophobicContact CG2-CB 4.07Å; T467-H471 PolarHBondContact N-O 3.5Å; T467-H471 WeakPolarHBondContact OG1-CB 3.23Å; T467-H471 PolarHBondContact OG1-N 3.05Å; E469-H471 PolarHBondContact O-N 3.3Å; H471-L473 PolarHBondContact O-N 3.06Å
472L97.4Very high88.9Confident0 Ų040.9 Ų40.90%024%0.239CC..EExtended strand (participates in β ladder)trans-85.9106.4-174.7-65.4170.1000112.9D89 M138 F459 Y464 F466D89-L472 PolarHBondContact OD2-N 3.13Å; M138-L472 HydrophobicContact CE-CB 4.08Å; M138-L472 HydrophobicContact CE-CD1 4.01Å; M138-L472 HydrophobicContact SD-CD1 4.22Å; F459-L472 HydrophobicContact CE2-CD1 3.86Å; F459-L472 HydrophobicContact CZ-CD1 3.55Å; Y464-L472 HydrophobicContact CD1-CB 3.92Å; Y464-L472 HydrophobicContact CG-CB 4.32Å; Y464-L472 HydrophobicContact CG-CD2 4.44Å; F466-L472 HydrophobicContact CD1-CD2 3.96Å; F466-L472 HydrophobicContact CD2-CD2 4.5Å; F466-L472 HydrophobicContact CE1-CD2 3.68Å; F466-L472 HydrophobicContact CE2-CD2 4.24Å; F466-L472 HydrophobicContact CG-CD2 4.36Å; F466-L472 HydrophobicContact CZ-CD2 3.83Å
473L97.7Very high86.8Confident0 Ų039.6 Ų39.60%025%0.245CC..EExtended strand (participates in β ladder)trans-104.5125.4172.5-61.5177.8000110.5L133 L211 A215 L282 Y464 V465 T467 H471L133-L473 HydrophobicContact CB-CD2 3.94Å; L211-L473 HydrophobicContact CB-CD1 3.92Å; A215-L473 HydrophobicContact CB-CD1 4.1Å; A215-L473 HydrophobicContact CB-CD2 3.97Å; L282-L473 HydrophobicContact CD1-CB 4.49Å; L282-L473 HydrophobicContact CD2-CD1 4.09Å; Y464-L473 CarbonylContact C-O 3.59Å; Y464-L473 WeakPolarHBondContact CA-O 3.27Å; V465-L473 HydrophobicContact CG1-CB 4.04Å; V465-L473 PolarHBondContact N-O 3.35Å; V465-L473 PolarHBondContact O-N 3.27Å; T467-L473 HydrophobicContact CG2-CD1 3.61Å; T467-L473 HydrophobicContact CG2-CG 3.98Å; H471-L473 PolarHBondContact O-N 3.06Å
474P96Very high84.4Confident15 Ų1536.8 Ų36.810%0.09723%0.233CC..EExtended strand (participates in β ladder)trans-73.6137-17325.5-31.6000112.8S137 F219 Y464 S476 L477S137-P474 WeakPolarHBondContact OG-CD 3.24Å; F219-P474 HydrophobicContact CZ-CG 4.04Å; Y464-P474 HydrophobicContact CD1-CB 3.89Å; Y464-P474 HydrophobicContact CE1-CB 3.71Å; Y464-P474 HydrophobicContact CE1-CG 4.34Å; P474-S476 PolarHBondContact O-N 2.77Å; P474-S476 VanDerWaalsContact O-N 3.14Å; P474-L477 HydrophobicContact CG-CD1 4.16Å; P474-L477 HydrophobicContact CG-CG 4.13Å; P474-L477 WeakPolarHBondContact O-CB 3.32Å; P474-L477 VanDerWaalsContact O-CG 3.22Å; P474-L477 WeakPolarHBondContact O-CG 3.47Å; P474-L477 PolarHBondContact O-N 3.43Å
475L94.3Very high81.5Confident50 Ų5040.1 Ų40.126%0.26226%0.262SS..G310 helixtrans-66-15.8-180-63.5-179.7000113.3I281 E462 D463 V465 L477 S478I281-L475 HydrophobicContact CG2-CD2 3.78Å; E462-L475 VanDerWaalsContact O-CD1 3.28Å; E462-L475 WeakPolarHBondContact O-CD1 3.32Å; D463-L475 WeakPolarHBondContact O-CB 3.24Å; D463-L475 WeakPolarHBondContact O-CG 3.47Å; D463-L475 PolarHBondContact O-N 3Å; V465-L475 HydrophobicContact CB-CD2 4Å; V465-L475 HydrophobicContact CG1-CD2 4.42Å; L475-L477 PolarHBondContact O-N 3.18Å; L475-L477 VanDerWaalsContact O-N 3.15Å; L475-S478 WeakPolarHBondContact O-CB 3.21Å; L475-S478 PolarHBondContact O-N 3.1Å; L475-S478 VanDerWaalsContact O-N 3.13Å; L475-S478 PolarHBondContact O-OG 3.35Å
476S90.2Very high78.7Confident74 Ų7446.8 Ų46.852%0.51730%0.295SS..G310 helixtrans-58.7-22.217361.40000113.3P474 S478 T479P474-S476 PolarHBondContact O-N 2.77Å; P474-S476 VanDerWaalsContact O-N 3.14Å; S476-S478 PolarHBondContact O-N 2.75Å; S476-T479 PolarHBondContact O-N 2.92Å; S476-T479 PolarHBondContact O-OG1 3.16Å
477L89.4Confident75.7Confident9 Ų951.8 Ų51.85%0.04733%0.329CS..G310 helixtrans-60.5-25.7175.3-62.2174.3000113.2A215 R218 F219 L282 P474 L475 T479 A480A215-L477 HydrophobicContact CB-CD1 3.85Å; R218-L477 HydrophobicContact CB-CB 4.43Å; R218-L477 HydrophobicContact CB-CD2 3.79Å; R218-L477 HydrophobicContact CG-CB 4.28Å; F219-L477 HydrophobicContact CD1-CD2 4.1Å; F219-L477 HydrophobicContact CD2-CD2 4.4Å; F219-L477 HydrophobicContact CE1-CD2 3.8Å; F219-L477 HydrophobicContact CE2-CD1 3.87Å; F219-L477 HydrophobicContact CE2-CD2 4.13Å; F219-L477 HydrophobicContact CG-CD2 4.38Å; F219-L477 HydrophobicContact CZ-CD1 3.96Å; F219-L477 HydrophobicContact CZ-CD2 3.81Å; F219-L477 HydrophobicContact CZ-CG 4.36Å; L282-L477 HydrophobicContact CD1-CB 4.11Å; L282-L477 HydrophobicContact CD1-CD1 4.22Å; P474-L477 HydrophobicContact CG-CD1 4.16Å; P474-L477 HydrophobicContact CG-CG 4.13Å; P474-L477 WeakPolarHBondContact O-CB 3.32Å; P474-L477 VanDerWaalsContact O-CG 3.22Å; P474-L477 WeakPolarHBondContact O-CG 3.47Å; P474-L477 PolarHBondContact O-N 3.43Å; L475-L477 PolarHBondContact O-N 3.18Å; L475-L477 VanDerWaalsContact O-N 3.15Å; L477-T479 PolarHBondContact O-N 3.43Å; L477-A480 WeakPolarHBondContact O-CB 3.02Å; L477-A480 PolarHBondContact O-N 2.86Å; L477-A480 VanDerWaalsContact O-N 3.16Å
478S83.2Confident72.7Confident56 Ų5656.6 Ų56.639%0.39236%0.363SS..G310 helixtrans-58-28.8170.263.20000113.3L282 L475 S476L282-S478 WeakPolarHBondContact O-CA 3.31Å; L282-S478 VanDerWaalsContact O-CB 3.31Å; L282-S478 WeakPolarHBondContact O-CB 3.37Å; L282-S478 PolarHBondContact O-N 3.04Å; L475-S478 WeakPolarHBondContact O-CB 3.21Å; L475-S478 PolarHBondContact O-N 3.1Å; L475-S478 VanDerWaalsContact O-N 3.13Å; L475-S478 PolarHBondContact O-OG 3.35Å; S476-S478 PolarHBondContact O-N 2.75Å
479T76Confident69.7Low117 Ų11762.7 Ų62.772%0.71839%0.394SS*.G310 helixtrans-92.3-8.9-17971.50000113.4S476 L477S476-T479 PolarHBondContact O-N 2.92Å; S476-T479 PolarHBondContact O-OG1 3.16Å; L477-T479 PolarHBondContact O-N 3.43Å
480A69.5Low66.8Low24 Ų2470.1 Ų70.120%0.19843%0.426CS..SBendtrans-70.2125.9179.500000110.3R218 L477 N482R218-A480 HydrophobicContact CB-CB 4.09Å; R218-A480 HydrophobicContact CG-CB 4.3Å; R218-A480 PolarHBondContact NH1-O 2.85Å; L477-A480 WeakPolarHBondContact O-CB 3.02Å; L477-A480 PolarHBondContact O-N 2.86Å; L477-A480 VanDerWaalsContact O-N 3.16Å; A480-N482 PolarHBondContact O-N 2.94Å
481P56.1Low63.9Low123 Ų12375.8 Ų75.880%0.79946%0.461SS*.  trans-63126.7-165.223.4-34.1000112.9A483P481-A483 PolarHBondContact O-N 3.23Å; P481-A483 VanDerWaalsContact O-N 3.13Å
482N50.4Low60.8Low96 Ų9680.6 Ų80.651%0.51350%0.495SS..  trans-57.4113.8170.9-83.4-34.8000110.6R218 A480 S484R218-N482 PolarHBondContact NH1-OD1 3.34Å; R218-N482 PolarHBondContact NH2-OD1 3.07Å; A480-N482 PolarHBondContact O-N 2.94Å; N482-S484 PolarHBondContact O-N 3.45Å
483A46.3Very low58Low71 Ų7186.7 Ų86.759%0.58753%0.528SS*.SBendtrans-65.8-28.9164.400000111.5P223 P481 S485P223-A483 HydrophobicContact CG-CB 4.31Å; P481-A483 PolarHBondContact O-N 3.23Å; P481-A483 VanDerWaalsContact O-N 3.13Å; A483-S485 VanDerWaalsContact C-N 3.29Å; A483-S485 PolarHBondContact O-N 3.44Å; A483-S485 VanDerWaalsContact O-N 3.09Å
484S43.6Very low55.1Low45 Ų4594.8 Ų94.832%0.31557%0.565SS.*  trans-82.958.2178.6420000112.7N482 I486N482-S484 PolarHBondContact O-N 3.45Å; S484-I486 VanDerWaalsContact C-N 3.29Å; S484-I486 PolarHBondContact O-N 3.27Å
485S35.8Very low52.2Low102 Ų102103.3 Ų103.371%0.71360%0.604SS**  trans-73.178.517368.10000111.7A483 P487A483-S485 VanDerWaalsContact C-N 3.29Å; A483-S485 PolarHBondContact O-N 3.44Å; A483-S485 VanDerWaalsContact O-N 3.09Å; S485-P487 WeakPolarHBondContact O-CD 3.41Å
486I38Very low49.5Very low149 Ų149108.4 Ų108.476%0.76463%0.631SS**  trans-67.4120168.6-59.4178.1000108S484 S488S484-I486 VanDerWaalsContact C-N 3.29Å; S484-I486 PolarHBondContact O-N 3.27Å; I486-S488 PolarHBondContact O-N 2.94Å
487P35.2Very low47Very low118 Ų118110.6 Ų110.677%0.76664%0.637SS**  trans-75.694.1179.430.5-33.5000109.9S485 N489S485-P487 WeakPolarHBondContact O-CD 3.41Å; P487-N489 PolarHBondContact O-N 3.45Å
488S34.4Very low44.7Very low102 Ų102117.9 Ų117.971%0.71368%0.676SS**  trans-65.7121.4168.254.50000109.5I486 K490I486-S488 PolarHBondContact O-N 2.94Å; S488-K490 PolarHBondContact O-N 2.78Å
489N34.5Very low42.6Very low155 Ų155119.2 Ų119.283%0.82969%0.685SS**  trans-67.4100.9173-86.4-34.4000108.8P487 T491P487-N489 PolarHBondContact O-N 3.45Å; N489-T491 PolarHBondContact O-N 2.9Å; N489-T491 VanDerWaalsContact O-N 3.07Å
490K38.5Very low40.9Very low166 Ų166117.4 Ų117.472%0.72267%0.671SS**  trans-55.4113171.1-88.2-159.8166.1-150.10110.5S488 D493S488-K490 PolarHBondContact O-N 2.78Å; K490-D493 IonicContact NZ-OD1 3.16Å; K490-D493 PolarHBondContact NZ-OD1 3.25Å
491T35.8Very low39.5Very low119 Ų119124.4 Ų124.473%0.7370%0.697SS**  trans-118.6118.5161.950.20000108.5N489N489-T491 PolarHBondContact O-N 2.9Å; N489-T491 VanDerWaalsContact O-N 3.07Å
492S34.6Very low39Very low102 Ų102124.8 Ų124.871%0.71369%0.692SS**  trans52.4109.1-179.443.80000115.8E494S492-E494 PolarHBondContact O-N 3.41Å; S492-E494 VanDerWaalsContact O-N 3.11Å
493D37.8Very low38.8Very low128 Ų128128.2 Ų128.268%0.68470%0.698SS**  trans-65.3102.7154.6-54.6-72.7000107.9K490K490-D493 IonicContact NZ-OD1 3.16Å; K490-D493 PolarHBondContact NZ-OD1 3.25Å
494E37.1Very low38.6Very low170 Ų170129 Ų12979%0.79470%0.696SS**  trans-78.2126.8159.3-68.3-167.9148.300107.4S492 L496S492-E494 PolarHBondContact O-N 3.41Å; S492-E494 VanDerWaalsContact O-N 3.11Å; E494-L496 PolarHBondContact O-N 2.73Å; E494-L496 VanDerWaalsContact O-N 3.14Å
495E34.4Very low38.7Very low194 Ų194132.8 Ų132.891%0.90772%0.721SS**  trans-64.6114.3176.9-67-179.8133.100108.7D497E495-D497 PolarHBondContact O-N 3.25Å
496L39.5Very low39.3Very low157 Ų157130.7 Ų130.782%0.82271%0.705SS**  trans-62.1131.5179.4-69.7171.4000110.1E494 D498E494-L496 PolarHBondContact O-N 2.73Å; E494-L496 VanDerWaalsContact O-N 3.14Å; L496-D498 PolarHBondContact O-N 2.73Å
497D37.2Very low39.6Very low120 Ų120127.8 Ų127.864%0.64269%0.691SS**  trans-7786179.6-170-9.8000110.5E495 S499 N500E495-D497 PolarHBondContact O-N 3.25Å; D497-S499 VanDerWaalsContact CG-OG 3.27Å; D497-S499 PolarHBondContact O-N 3.27Å; D497-S499 WeakPolarHBondContact OD1-CB 3.41Å; D497-S499 PolarHBondContact OD1-N 3.06Å; D497-S499 VanDerWaalsContact OD1-N 3.14Å; D497-S499 PolarHBondContact OD1-OG 3.17Å; D497-S499 PolarHBondContact OD2-OG 2.91Å; D497-N500 PolarHBondContact O-N 3.09Å
498D40.6Very low40.3Very low162 Ų162124.7 Ų124.787%0.86667%0.67SS**THydrogen-bonded Turntrans-56.9-0.3175.2-84.6-15.8000114.3L496 N500L496-D498 PolarHBondContact O-N 2.73Å; D498-N500 VanDerWaalsContact C-N 3.27Å; D498-N500 PolarHBondContact O-N 2.89Å
499S38.8Very low40.9Very low83 Ų83130.2 Ų130.258%0.5868%0.675SS**THydrogen-bonded Turntrans-76.4-10.2174.2740000114.2D497 F501D497-S499 VanDerWaalsContact CG-OG 3.27Å; D497-S499 PolarHBondContact O-N 3.27Å; D497-S499 WeakPolarHBondContact OD1-CB 3.41Å; D497-S499 PolarHBondContact OD1-N 3.06Å; D497-S499 VanDerWaalsContact OD1-N 3.14Å; D497-S499 PolarHBondContact OD1-OG 3.17Å; D497-S499 PolarHBondContact OD2-OG 2.91Å; S499-F501 PolarHBondContact O-N 3.06Å
500N41.4Very low41.7Very low80 Ų80129.7 Ų129.743%0.42867%0.671SS.*  trans-87.1113.3-172.1-156.824.1000113.5D497 D498 D502D497-N500 PolarHBondContact O-N 3.09Å; D498-N500 VanDerWaalsContact C-N 3.27Å; D498-N500 PolarHBondContact O-N 2.89Å; N500-D502 PolarHBondContact ND2-OD2 2.86Å; N500-D502 PolarHBondContact O-N 3.34Å; N500-D502 VanDerWaalsContact O-N 3.1Å; N500-D502 PolarHBondContact OD1-OD2 2.97Å
501F39.8Very low42.2Very low170 Ų170125.6 Ų125.675%0.74666%0.657SS**G310 helixtrans-63.8-12.8180-88.9-99.8000114.5S499 W503 T504S499-F501 PolarHBondContact O-N 3.06Å; F501-W503 PolarHBondContact O-N 2.87Å; F501-T504 PolarHBondContact O-N 2.81Å; F501-T504 PolarHBondContact O-OG1 3.04Å
502D46.2Very low43.2Very low131 Ų131121.7 Ų121.770%0.70163%0.63SS**G310 helixtrans-57.2-19.4-178-68-16.7000114.3N500N500-D502 PolarHBondContact ND2-OD2 2.86Å; N500-D502 PolarHBondContact O-N 3.34Å; N500-D502 VanDerWaalsContact O-N 3.1Å; N500-D502 PolarHBondContact OD1-OD2 2.97Å
503W44.7Very low44.1Very low169 Ų169122.2 Ų122.264%0.6463%0.631SS**G310 helixtrans-92.8-2.2177.8-59.6109.9000114.6L289 F501L289-W503 HydrophobicContact CD2-CZ3 3.9Å; F501-W503 PolarHBondContact O-N 2.87Å
504T43.1Very low45.1Very low88 Ų88120.5 Ų120.554%0.5462%0.622SS.*SBendtrans-96.9127173.240.30000111.8F501F501-T504 PolarHBondContact O-N 2.81Å; F501-T504 PolarHBondContact O-OG1 3.04Å
505C45Very low46.4Very low124 Ų124118 Ų11884%0.83862%0.62SS**  trans-51.6124.1167.4-73.40000109.5N507C505-N507 PolarHBondContact O-N 3.05Å
506P48.5Very low48Very low57 Ų57110.9 Ų110.937%0.3760%0.595SS.*  trans-67.9110.1-168.924.4-33000110.8T508 L511P506-T508 PolarHBondContact O-N 3.05Å; P506-T508 VanDerWaalsContact O-N 3.08Å; P506-L511 HydrophobicContact CB-CD1 3.94Å; P506-L511 HydrophobicContact CB-CG 4.45Å; P506-L511 HydrophobicContact CG-CD1 4.46Å
507N45.2Very low49.6Very low88 Ų88107.1 Ų107.147%0.47157%0.572SS.*  trans-58.7115.6-176.9-178.3-24.3000110.5C505 R509 L510 L511C505-N507 PolarHBondContact O-N 3.05Å; N507-R509 PolarHBondContact O-N 2.95Å; N507-R509 VanDerWaalsContact O-N 3.16Å; N507-R509 WeakPolarHBondContact OD1-CB 3.3Å; N507-R509 PolarHBondContact OD1-N 3Å; N507-L510 HydrophobicContact CB-CB 4.41Å; N507-L510 HydrophobicContact CB-CD1 4.15Å; N507-L510 WeakPolarHBondContact O-CA 3.36Å; N507-L510 WeakPolarHBondContact O-CB 3.12Å; N507-L510 PolarHBondContact O-N 2.96Å; N507-L511 PolarHBondContact O-N 2.96Å
508T48.3Very low51.5Low53 Ų53101.8 Ų101.833%0.32554%0.543SS..Hα-helixtrans-65.5-23.5-172.258.60000112.5A393 P506 L510 L511 F512A393-T508 WeakPolarHBondContact O-CB 3.41Å; A393-T508 VanDerWaalsContact O-CG2 3.31Å; A393-T508 WeakPolarHBondContact O-CG2 3.49Å; A393-T508 PolarHBondContact O-OG1 2.92Å; P506-T508 PolarHBondContact O-N 3.05Å; P506-T508 VanDerWaalsContact O-N 3.08Å; T508-L510 VanDerWaalsContact C-N 3.29Å; T508-L510 PolarHBondContact O-N 2.69Å; T508-L511 PolarHBondContact O-N 2.77Å; T508-F512 WeakPolarHBondContact O-CB 3.23Å; T508-F512 VanDerWaalsContact O-CD2 3.31Å; T508-F512 WeakPolarHBondContact O-CD2 3.35Å; T508-F512 PolarHBondContact O-N 3.13Å
509R48.5Very low53.2Low219 Ų21999.9 Ų99.983%0.82652%0.524SS*.Hα-helixtrans-72.5-17.6171.1-62.1-178175.5171.10.6114.1N507N507-R509 PolarHBondContact O-N 2.95Å; N507-R509 VanDerWaalsContact O-N 3.16Å; N507-R509 WeakPolarHBondContact OD1-CB 3.3Å; N507-R509 PolarHBondContact OD1-N 3Å
510L50.8Low55.2Low143 Ų14399.1 Ų99.175%0.74952%0.519SS*.Hα-helixtrans-91.6-30.9172.5-82.2163.1000112.1N507 T508N507-L510 HydrophobicContact CB-CB 4.41Å; N507-L510 HydrophobicContact CB-CD1 4.15Å; N507-L510 WeakPolarHBondContact O-CA 3.36Å; N507-L510 WeakPolarHBondContact O-CB 3.12Å; N507-L510 PolarHBondContact O-N 2.96Å; T508-L510 VanDerWaalsContact C-N 3.29Å; T508-L510 PolarHBondContact O-N 2.69Å
511L49.6Very low56.9Low80 Ų8096.3 Ų96.342%0.41950%0.504SS..Hα-helixtrans-76.2-32.6172.8-68.4-174.6000113.6I342 P506 N507 T508 P513I342-L511 HydrophobicContact CG1-CD1 4.33Å; P506-L511 HydrophobicContact CB-CD1 3.94Å; P506-L511 HydrophobicContact CB-CG 4.45Å; P506-L511 HydrophobicContact CG-CD1 4.46Å; N507-L511 PolarHBondContact O-N 2.96Å; T508-L511 PolarHBondContact O-N 2.77Å; L511-P513 WeakPolarHBondContact O-CD 3.41Å
512F55.9Low59Low37 Ų3788.8 Ų88.816%0.16247%0.47CS..  trans-118.770.9-175.2-57.5-69.2000113I342 I346 T394 T508 D514 F517 P518I342-F512 HydrophobicContact CB-CE2 4.3Å; I342-F512 HydrophobicContact CB-CZ 3.84Å; I342-F512 HydrophobicContact CG1-CE2 4.25Å; I342-F512 HydrophobicContact CG1-CZ 4.28Å; I342-F512 HydrophobicContact CG2-CE2 4.11Å; I342-F512 HydrophobicContact CG2-CZ 3.66Å; I346-F512 HydrophobicContact CD1-CE1 4.21Å; I346-F512 HydrophobicContact CD1-CZ 4.27Å; T394-F512 HydrophobicContact CG2-CE2 4.14Å; T394-F512 HydrophobicContact CG2-CZ 4.29Å; T508-F512 WeakPolarHBondContact O-CB 3.23Å; T508-F512 VanDerWaalsContact O-CD2 3.31Å; T508-F512 WeakPolarHBondContact O-CD2 3.35Å; T508-F512 PolarHBondContact O-N 3.13Å; F512-D514 PolarHBondContact O-N 2.96Å; F512-F517 AromaticContact CD1-CD1 3.67Å; F512-F517 HydrophobicContact CD1-CD1 3.67Å; F512-F517 HydrophobicContact CD1-CE1 4.24Å; F512-F517 HydrophobicContact CD1-CG 4.48Å; F512-F517 AromaticContact CE1-CD1 3.59Å; F512-F517 HydrophobicContact CE1-CD1 3.59Å; F512-F517 AromaticContact CE1-CE1 3.79Å; F512-F517 HydrophobicContact CE1-CE1 3.79Å; F512-P518 HydrophobicContact CD1-CG 4.16Å; F512-P518 HydrophobicContact CE1-CG 4.23Å
513P52.5Low60.6Low114 Ų11488 Ų8874%0.7446%0.462SS*.SBendtrans-72.6-12.3175.531.3-36.5000113.8L511L511-P513 WeakPolarHBondContact O-CD 3.41Å
514D60.8Low62.2Low91 Ų9183.9 Ų83.949%0.48746%0.458SS..SBendtrans-134.4119.3178.3-175.8-5.9000110.6F512 A516 F517F512-D514 PolarHBondContact O-N 2.96Å; D514-A516 PolarHBondContact O-N 3.16Å; D514-A516 VanDerWaalsContact O-N 3.07Å; D514-A516 VanDerWaalsContact OD1-CB 3.31Å; D514-A516 WeakPolarHBondContact OD1-CB 3.45Å; D514-A516 PolarHBondContact OD1-N 3.33Å; D514-F517 WeakPolarHBondContact O-CB 3.35Å; D514-F517 PolarHBondContact O-N 3.1Å
515P63.1Low63.9Low118 Ų11880.6 Ų80.677%0.76644%0.437SS*.THydrogen-bonded Turntrans-57.8-14.5172.8-25.535.5000115.2F517P515-F517 VanDerWaalsContact C-N 3.32Å
516A68Low65.3Low45 Ų4581.8 Ų81.837%0.37242%0.423SS..Hα-helixtrans-76-15.1172.100000113.7D514 R519 S520D514-A516 PolarHBondContact O-N 3.16Å; D514-A516 VanDerWaalsContact O-N 3.07Å; D514-A516 VanDerWaalsContact OD1-CB 3.31Å; D514-A516 WeakPolarHBondContact OD1-CB 3.45Å; D514-A516 PolarHBondContact OD1-N 3.33Å; A516-R519 WeakPolarHBondContact O-CB 3.36Å; A516-R519 PolarHBondContact O-N 3.26Å; A516-S520 PolarHBondContact O-N 2.85Å
517F74.4Confident65.8Low78 Ų7881 Ų8134%0.34242%0.419SS..Hα-helixtrans-63.4-49.9-177177.9-86000113.3F512 D514 P515 R519 S520 L521F512-F517 AromaticContact CD1-CD1 3.67Å; F512-F517 HydrophobicContact CD1-CD1 3.67Å; F512-F517 HydrophobicContact CD1-CE1 4.24Å; F512-F517 HydrophobicContact CD1-CG 4.48Å; F512-F517 AromaticContact CE1-CD1 3.59Å; F512-F517 HydrophobicContact CE1-CD1 3.59Å; F512-F517 AromaticContact CE1-CE1 3.79Å; F512-F517 HydrophobicContact CE1-CE1 3.79Å; D514-F517 WeakPolarHBondContact O-CB 3.35Å; D514-F517 PolarHBondContact O-N 3.1Å; P515-F517 VanDerWaalsContact C-N 3.32Å; F517-R519 PolarHBondContact O-N 3.07Å; F517-S520 PolarHBondContact O-N 2.97Å; F517-S520 PolarHBondContact O-OG 3.02Å; F517-S520 VanDerWaalsContact O-OG 3.05Å; F517-L521 HydrophobicContact CD1-CD1 4.27Å; F517-L521 HydrophobicContact CE1-CD1 3.69Å; F517-L521 HydrophobicContact CE1-CG 4.36Å; F517-L521 HydrophobicContact CZ-CD1 4.17Å; F517-L521 PolarHBondContact O-N 3.37Å
518P76.4Confident66.7Low7 Ų778.5 Ų78.55%0.04541%0.411CS..Hα-helixtrans-59.9-32.4174.6-2435.1000112.8I346 F512 R522I346-P518 HydrophobicContact CD1-CB 4.25Å; F512-P518 HydrophobicContact CD1-CG 4.16Å; F512-P518 HydrophobicContact CE1-CG 4.23Å; P518-R522 WeakPolarHBondContact O-CG 3.39Å; P518-R522 PolarHBondContact O-N 2.84Å
519R76.9Confident67.1Low123 Ų12376.1 Ų76.146%0.46440%0.396SS..Hα-helixtrans-66.9-42.4177.1-174.3-177.2-62.4-171.90.1112.4A516 F517 L521 R522 E523A516-R519 WeakPolarHBondContact O-CB 3.36Å; A516-R519 PolarHBondContact O-N 3.26Å; F517-R519 PolarHBondContact O-N 3.07Å; R519-L521 VanDerWaalsContact C-N 3.26Å; R519-L521 PolarHBondContact O-N 3.33Å; R519-R522 PolarHBondContact O-N 2.9Å; R519-E523 VanDerWaalsContact CD-OE1 3.28Å; R519-E523 WeakPolarHBondContact CD-OE1 3.29Å; R519-E523 HydrophobicContact CG-CG 4.15Å; R519-E523 WeakPolarHBondContact CG-OE1 3.45Å; R519-E523 PolarHBondContact O-N 3.11Å
520S79.3Confident67.3Low67 Ų6771 Ų7147%0.46939%0.386SS..Hα-helixtrans-68.6-24.6-178.1720000113.3A516 F517 P524A516-S520 PolarHBondContact O-N 2.85Å; F517-S520 PolarHBondContact O-N 2.97Å; F517-S520 PolarHBondContact O-OG 3.02Å; F517-S520 VanDerWaalsContact O-OG 3.05Å; S520-P524 WeakPolarHBondContact O-CD 3.33Å
521L78.6Confident67.2Low20 Ų2070.1 Ų70.111%0.10538%0.375CS..Hα-helixtrans-70.5-37.8168.4-60.8178.5000112.5R343 I346 E347 F517 R519R343-L521 HydrophobicContact CB-CD1 4.37Å; R343-L521 HydrophobicContact CG-CD1 3.91Å; R343-L521 HydrophobicContact CG-CD2 4.29Å; I346-L521 HydrophobicContact CB-CD1 4.11Å; I346-L521 HydrophobicContact CD1-CD1 3.9Å; I346-L521 HydrophobicContact CG2-CB 3.95Å; I346-L521 HydrophobicContact CG2-CD1 4Å; E347-L521 HydrophobicContact CG-CB 4.39Å; F517-L521 HydrophobicContact CD1-CD1 4.27Å; F517-L521 HydrophobicContact CE1-CD1 3.69Å; F517-L521 HydrophobicContact CE1-CG 4.36Å; F517-L521 HydrophobicContact CZ-CD1 4.17Å; F517-L521 PolarHBondContact O-N 3.37Å; R519-L521 VanDerWaalsContact C-N 3.26Å; R519-L521 PolarHBondContact O-N 3.33Å
522R82.3Confident67Low13 Ų1368.4 Ų68.45%0.04937%0.37CS..Hα-helixtrans-77.9-39.4-177.6-64.3179.4-161.3124.59.8113.9I346 E350 D396 Y398 Y399 P518 R519 P524 I525 R526I346-R522 HydrophobicContact CG2-CG 4.05Å; E350-R522 HydrophobicContact CB-CG 4.03Å; E350-R522 HydrophobicContact CG-CB 3.9Å; E350-R522 HydrophobicContact CG-CG 3.92Å; D396-R522 IonicContact OD1-NH1 2.7Å; D396-R522 IonicContact OD2-CZ 3.34Å; D396-R522 IonicContact OD2-NH1 3.33Å; D396-R522 PolarHBondContact OD2-NH1 2.94Å; D396-R522 IonicContact OD2-NH2 3.94Å; D396-R522 PolarHBondContact OD2-NH2 3.1Å; Y398-R522 VanDerWaalsContact CD1-CZ 3.44Å; Y399-R522 VanDerWaalsContact CZ-NH2 3.25Å; Y399-R522 PolarHBondContact OH-NH2 2.98Å; P518-R522 WeakPolarHBondContact O-CG 3.39Å; P518-R522 PolarHBondContact O-N 2.84Å; R519-R522 PolarHBondContact O-N 2.9Å; R522-P524 VanDerWaalsContact C-CD 3.48Å; R522-I525 PolarHBondContact O-N 3.22Å; R522-R526 WeakPolarHBondContact O-CB 3.23Å; R522-R526 PolarHBondContact O-N 2.87Å
523E80.3Confident65.9Low114 Ų11469.4 Ų69.453%0.53338%0.381SS..Hα-helixtrans-53.6-38.9-173.5-79.8179.5-172.500115.5R519R519-E523 VanDerWaalsContact CD-OE1 3.28Å; R519-E523 WeakPolarHBondContact CD-OE1 3.29Å; R519-E523 HydrophobicContact CG-CG 4.15Å; R519-E523 WeakPolarHBondContact CG-OE1 3.45Å; R519-E523 PolarHBondContact O-N 3.11Å
524P79Confident65.1Low83 Ų8370.1 Ų70.154%0.53939%0.386SS..Hα-helixtrans-60.7-43.5171.6-24.834.9000113.6S520 R522 S527S520-P524 WeakPolarHBondContact O-CD 3.33Å; R522-P524 VanDerWaalsContact C-CD 3.48Å; P524-S527 PolarHBondContact O-OG 2.67Å
525I78.1Confident63.6Low19 Ų1975 Ų7510%0.09740%0.397CS..Hα-helixtrans-79.6-37.8-171.9-54.7174.3000111.1P307 E347 E350 M351 R522 S527 A528P307-I525 HydrophobicContact CB-CD1 4.02Å; E347-I525 HydrophobicContact CB-CD1 4.02Å; E347-I525 HydrophobicContact CG-CD1 4.33Å; E347-I525 VanDerWaalsContact O-CD1 3.29Å; E347-I525 WeakPolarHBondContact O-CD1 3.14Å; E350-I525 HydrophobicContact CB-CG2 4.39Å; E350-I525 HydrophobicContact CG-CB 3.85Å; E350-I525 HydrophobicContact CG-CG2 3.84Å; M351-I525 HydrophobicContact CB-CG2 4.17Å; R522-I525 PolarHBondContact O-N 3.22Å; I525-S527 PolarHBondContact O-N 2.03Å; I525-A528 WeakPolarHBondContact O-CB 3.37Å; I525-A528 PolarHBondContact O-N 3.33Å
526R73.9Confident62.4Low148 Ų14875.4 Ų75.456%0.55840%0.4SS*.THydrogen-bonded Turntrans-51.2-20.8177.2-176.8168.9-178.4-176.24.6114.7E350 R522E350-R526 WeakPolarHBondContact OE1-CB 3.41Å; R522-R526 WeakPolarHBondContact O-CB 3.23Å; R522-R526 PolarHBondContact O-N 2.87Å
527S60.7Low60.7Low40 Ų4077 Ų7728%0.2841%0.413SS..THydrogen-bonded Turntrans-116.60176.561.60000114.3P524 I525 K531P524-S527 PolarHBondContact O-OG 2.67Å; I525-S527 PolarHBondContact O-N 2.03Å; S527-K531 WeakPolarHBondContact O-CB 3.4Å; S527-K531 WeakPolarHBondContact O-CD 3.4Å; S527-K531 WeakPolarHBondContact O-CG 3Å; S527-K531 PolarHBondContact O-N 3.02Å; S527-K531 VanDerWaalsContact O-N 3.1Å; S527-K531 WeakPolarHBondContact OG-CE 3.38Å; S527-K531 PolarHBondContact OG-NZ 3Å
528A63.3Low58.8Low36 Ų3678.6 Ų78.630%0.29843%0.432SS..Hα-helixtrans-68.6-44.5177.600000111.2I525 D530 K531 S532I525-A528 WeakPolarHBondContact O-CB 3.37Å; I525-A528 PolarHBondContact O-N 3.33Å; A528-D530 PolarHBondContact O-N 3.23Å; A528-K531 PolarHBondContact O-N 3.14Å; A528-K531 VanDerWaalsContact O-N 3.17Å; A528-S532 PolarHBondContact O-N 3.23Å
529V57.3Low56.9Low4 Ų488.9 Ų88.92%0.02447%0.471CS..Hα-helixtrans-66.8-34.9178.7-179.80000112.3Q354 K358 F370 S532Q354-V529 HydrophobicContact CB-CB 3.93Å; Q354-V529 HydrophobicContact CB-CG1 4.37Å; Q354-V529 HydrophobicContact CB-CG2 3.47Å; Q354-V529 VanDerWaalsContact CB-CG2 3.47Å; Q354-V529 HydrophobicContact CG-CG2 4.41Å; K358-V529 HydrophobicContact CB-CG1 4.24Å; K358-V529 HydrophobicContact CD-CG1 3.54Å; K358-V529 HydrophobicContact CG-CG1 4.48Å; F370-V529 HydrophobicContact CB-CG1 4.17Å; F370-V529 HydrophobicContact CB-CG2 4.41Å; F370-V529 HydrophobicContact CD1-CG2 4.34Å; F370-V529 HydrophobicContact CD2-CB 4.28Å; F370-V529 HydrophobicContact CD2-CG2 3.69Å; F370-V529 HydrophobicContact CE2-CG2 3.99Å; F370-V529 HydrophobicContact CG-CG1 4.49Å; F370-V529 HydrophobicContact CG-CG2 3.87Å; F370-V529 HydrophobicContact CZ-CG2 4.44Å; V529-S532 PolarHBondContact O-OG 3.31Å
530D52.5Low55.1Low112 Ų11292 Ų9260%0.59948%0.483SS*.Hα-helixtrans-72.6-28.1172.3-83.4-21.2000113.3A528 S532 C533A528-D530 PolarHBondContact O-N 3.23Å; D530-S532 VanDerWaalsContact C-N 3.29Å; D530-S532 PolarHBondContact O-N 2.87Å; D530-C533 WeakPolarHBondContact O-CB 3.37Å; D530-C533 PolarHBondContact O-N 3.21Å
531K48.4Very low53Low123 Ų12397.1 Ų97.154%0.53550%0.499SS..Hα-helixtrans-73.6-17.5177.6-76.3159.4-169.1154.30112.9S527 A528 C533S527-K531 WeakPolarHBondContact O-CB 3.4Å; S527-K531 WeakPolarHBondContact O-CD 3.4Å; S527-K531 WeakPolarHBondContact O-CG 3Å; S527-K531 PolarHBondContact O-N 3.02Å; S527-K531 VanDerWaalsContact O-N 3.1Å; S527-K531 WeakPolarHBondContact OG-CE 3.38Å; S527-K531 PolarHBondContact OG-NZ 3Å; A528-K531 PolarHBondContact O-N 3.14Å; A528-K531 VanDerWaalsContact O-N 3.17Å; K531-C533 VanDerWaalsContact C-N 3.32Å
532S44.5Very low51Low45 Ų45102.8 Ų102.832%0.31554%0.537SS..THydrogen-bonded Turntrans-83.6-4.7170.174.90000113.8K358 D369 A528 V529 D530K358-S532 PolarHBondContact NZ-OG 3.1Å; D369-S532 PolarHBondContact O-OG 3.05Å; A528-S532 PolarHBondContact O-N 3.23Å; V529-S532 PolarHBondContact O-OG 3.31Å; D530-S532 VanDerWaalsContact C-N 3.29Å; D530-S532 PolarHBondContact O-N 2.87Å
533C32.8Very low49.3Very low57 Ų57105.6 Ų105.639%0.38557%0.57SS.*SBendtrans-76.5137.4166.9-69.10000111D530 K531 R535D530-C533 WeakPolarHBondContact O-CB 3.37Å; D530-C533 PolarHBondContact O-N 3.21Å; K531-C533 VanDerWaalsContact C-N 3.32Å; C533-R535 PolarHBondContact O-N 2.91Å
534P35.6Very low47.6Very low130 Ų130108.3 Ų108.384%0.84459%0.585SS**  trans-66.5106.5173.227.9-33.3000109.4
535R31.2Very low46.1Very low192 Ų192108.3 Ų108.373%0.72560%0.6SS**PPolyproline II helixtrans-55.9140.1174.4-68.7-179.7174.6-178.5-3109.9C533 A537C533-R535 PolarHBondContact O-N 2.91Å; R535-A537 PolarHBondContact O-N 3.13Å
536P36.9Very low45Very low127 Ų127115.3 Ų115.383%0.82563%0.625SS**SBendtrans-54.3128.1162.725.4-32.8000107.7
537A32.2Very low44.2Very low79 Ų79112.5 Ų112.565%0.65363%0.626SS**PPolyproline II helixtrans-54.7133.2-158.200000112.3R535R535-A537 PolarHBondContact O-N 3.13Å
538P34.7Very low44.3Very low111 Ų111113.7 Ų113.772%0.72163%0.633SS**PPolyproline II helixtrans-57.8145.9175.925.7-33.8000110.2R540P538-R540 PolarHBondContact O-N 2.85Å
539Y36Very low44.9Very low223 Ų223113 Ų11388%0.87562%0.624SS**  trans-49.3109.9-170.6-165.1-90000111.6E541Y539-E541 PolarHBondContact O-N 3.12Å
540R39.1Very low45.9Very low189 Ų189118.3 Ų118.371%0.71364%0.643SS**  trans-60.9128.7-178.4-76.7-177.6171.9166.7-1.9110.2P538P538-R540 PolarHBondContact O-N 2.85Å
541E35.3Very low47.2Very low175 Ų175113.3 Ų113.382%0.81862%0.617SS**  trans-60.5133.7164.7-70-162.7142.100109.8Y539 G543Y539-E541 PolarHBondContact O-N 3.12Å; E541-G543 PolarHBondContact O-N 3.18Å
542P36.8Very low48.3Very low139 Ų139113.4 Ų113.490%0.90362%0.62SS**THydrogen-bonded Turntrans-75.873.8-179.431.5-35.4000111
543G47.1Very low49.9Very low71 Ų71115 Ų11573%0.73263%0.625SS**THydrogen-bonded Turntrans-153.4-30.6-177.100000116.9E541E541-G543 PolarHBondContact O-N 3.18Å
544M44.3Very low52.2Low172 Ų172114 Ų11485%0.84761%0.614SS**  trans-113.5114.5179.6-65.1-159.4-173.200112.2
545G48.3Very low54.1Low82 Ų82113 Ų11385%0.84560%0.599SS**  trans-98.819.5-163.700000117.7
546R53.8Low56Low167 Ų167105.8 Ų105.863%0.6358%0.581SS**SBendtrans-141.3146.1174.7-69.6-170.2178.4-170.21.4111.2E560R546-E560 IonicContact CZ-OE2 3.65Å; R546-E560 IonicContact NH1-OE2 3.25Å; R546-E560 PolarHBondContact NH1-OE2 3.32Å; R546-E560 IonicContact NH2-OE2 3.05Å
547P56.4Low57.7Low88 Ų88107.3 Ų107.357%0.57158%0.582SS**PPolyproline II helixtrans-70.2162171.232.1-35.5000111.5
548P64.6Low59.9Low66 Ų66105.5 Ų105.543%0.42956%0.561SS.*PPolyproline II helixtrans-64.3152.4169.528.9-34.8000111D597P548-D597 HydrophobicContact CB-CB 4.28Å
549L74.9Confident62Low21 Ų21104.9 Ų104.911%0.1156%0.558CS.*PPolyproline II helixtrans-80.2129.6175.8-177.364000109.4D553 F554 H561 L564 F601L549-D553 HydrophobicContact CD1-CB 4.03Å; L549-F554 HydrophobicContact CD2-CD2 3.97Å; L549-H561 HydrophobicContact CD2-CB 3.62Å; L549-L564 HydrophobicContact CB-CD2 3.91Å; L549-F601 HydrophobicContact CG-CE2 4.46Å; L549-F601 WeakPolarHBondContact O-CD2 3.49Å
550R78.7Confident63.9Low115 Ų11599.1 Ų99.143%0.43454%0.539SS..PPolyproline II helixtrans-89.6160173.2-60.3-173-56.9154.811111.1Q552 D553 F554 E604R550-Q552 PolarHBondContact O-N 3.5Å; R550-D553 IonicContact CZ-OD2 3.87Å; R550-D553 VanDerWaalsContact CZ-OD2 3.32Å; R550-D553 IonicContact NE-OD2 3.62Å; R550-D553 PolarHBondContact NE-OD2 3.09Å; R550-D553 IonicContact NH2-OD1 2.75Å; R550-D553 IonicContact NH2-OD2 3.49Å; R550-D553 PolarHBondContact NH2-OD2 3.2Å; R550-D553 PolarHBondContact O-N 2.72Å; R550-F554 PolarHBondContact O-N 3.09Å; R550-E604 WeakPolarHBondContact CA-OE2 3.01Å; R550-E604 WeakPolarHBondContact CB-OE2 3.44Å
551A79Confident66Low7 Ų791.6 Ų91.66%0.05851%0.512CS..G310 helixtrans-62.8-40.7179.300000113D553 F554 F601 E604 M605 L608A551-D553 PolarHBondContact O-N 3Å; A551-F554 VanDerWaalsContact O-CB 3.26Å; A551-F554 WeakPolarHBondContact O-CB 3.24Å; A551-F554 PolarHBondContact O-N 2.94Å; A551-F554 VanDerWaalsContact O-N 3.09Å; A551-F601 HydrophobicContact CB-CE2 4.32Å; A551-E604 HydrophobicContact CB-CB 3.41Å; A551-E604 VanDerWaalsContact CB-CB 3.41Å; A551-E604 PolarHBondContact N-OE2 2.87Å; A551-M605 HydrophobicContact CB-CB 4.37Å; A551-M605 HydrophobicContact CB-CG 3.67Å; A551-M605 HydrophobicContact CB-SD 3.65Å; A551-L608 HydrophobicContact CB-CD1 3.66Å
552Q72.9Confident68.2Low126 Ų12686.4 Ų86.459%0.58949%0.489SS*.G310 helixtrans-60.3-30.1177.2-64.8178.4-7.600112.9R550 L608R550-Q552 PolarHBondContact O-N 3.5Å; Q552-L608 HydrophobicContact CG-CD1 3.84Å; Q552-L608 HydrophobicContact CG-CD2 4.04Å; Q552-L608 HydrophobicContact CG-CG 4.5Å
553D76.4Confident70.3Confident78 Ų7882.6 Ų82.642%0.41746%0.459SS..G310 helixtrans-93.52.2-177.9-58.3-63.1000111.8L549 R550 A551 H561L549-D553 HydrophobicContact CD1-CB 4.03Å; R550-D553 IonicContact CZ-OD2 3.87Å; R550-D553 VanDerWaalsContact CZ-OD2 3.32Å; R550-D553 IonicContact NE-OD2 3.62Å; R550-D553 PolarHBondContact NE-OD2 3.09Å; R550-D553 IonicContact NH2-OD1 2.75Å; R550-D553 IonicContact NH2-OD2 3.49Å; R550-D553 PolarHBondContact NH2-OD2 3.2Å; R550-D553 PolarHBondContact O-N 2.72Å; A551-D553 PolarHBondContact O-N 3Å; D553-H561 PolarHBondContact O-CE1 3.48Å; D553-H561 PolarHBondContact O-ND1 2.95Å
554F82.4Confident72Confident37 Ų3781.3 Ų81.316%0.16244%0.435CS..  trans-74.5147-176.8-177.9-117.5000113.2L549 R550 A551 A556 H561 L562 L565 L572 F601L549-F554 HydrophobicContact CD2-CD2 3.97Å; R550-F554 PolarHBondContact O-N 3.09Å; A551-F554 VanDerWaalsContact O-CB 3.26Å; A551-F554 WeakPolarHBondContact O-CB 3.24Å; A551-F554 PolarHBondContact O-N 2.94Å; A551-F554 VanDerWaalsContact O-N 3.09Å; F554-A556 HydrophobicContact CE1-CB 4.01Å; F554-A556 HydrophobicContact CZ-CB 4.18Å; F554-H561 HydrophobicContact CD2-CB 4.1Å; F554-H561 HydrophobicContact CE2-CB 4.09Å; F554-L562 HydrophobicContact CZ-CD2 4.38Å; F554-L565 HydrophobicContact CD2-CD1 4.18Å; F554-L565 HydrophobicContact CE2-CD1 3.41Å; F554-L565 VanDerWaalsContact CE2-CD1 3.41Å; F554-L565 HydrophobicContact CE2-CG 4.01Å; F554-L565 HydrophobicContact CZ-CD1 3.67Å; F554-L572 HydrophobicContact CE1-CD1 4.4Å; F554-L572 HydrophobicContact CZ-CD1 3.87Å; F554-F601 HydrophobicContact CB-CE2 3.94Å; F554-F601 HydrophobicContact CB-CZ 3.83Å; F554-F601 HydrophobicContact CD1-CZ 4.18Å; F554-F601 HydrophobicContact CD2-CE2 4.32Å; F554-F601 AromaticContact CD2-CZ 3.87Å; F554-F601 HydrophobicContact CD2-CZ 3.87Å; F554-F601 HydrophobicContact CG-CE2 4.21Å; F554-F601 AromaticContact CG-CZ 3.68Å; F554-F601 HydrophobicContact CG-CZ 3.68Å
555M75.3Confident73.9Confident107 Ų10773.2 Ų73.253%0.52740%0.396SS..  trans-144.1112174-72.6-173.5-7900108.7N557 N558 H561M555-N557 PolarHBondContact O-N 3.05Å; M555-N557 VanDerWaalsContact O-N 3.09Å; M555-N558 HydrophobicContact CB-CB 3.94Å; M555-N558 HydrophobicContact CE-CB 4.44Å; M555-N558 PolarHBondContact O-N 2.86Å; M555-H561 PolarHBondContact N-ND1 3.21Å
556A70.8Confident75.6Confident41 Ų4177 Ų7734%0.33938%0.384SS..THydrogen-bonded Turntrans-58.5-25.4-177.600000113.7F554F554-A556 HydrophobicContact CE1-CB 4.01Å; F554-A556 HydrophobicContact CZ-CB 4.18Å
557N72Confident77Confident160 Ų16075.1 Ų75.186%0.85638%0.377SS*.THydrogen-bonded Turntrans-90.9-2.9-179.7-62.1-12.1000113.8M555 P559M555-N557 PolarHBondContact O-N 3.05Å; M555-N557 VanDerWaalsContact O-N 3.09Å; N557-P559 WeakPolarHBondContact O-CD 3.31Å
558N79.7Confident78.4Confident40 Ų4071.5 Ų71.521%0.21435%0.353CS..  trans-91.2115.1-179.5-177.4-5.3000111.2M555 E560 H561 L562M555-N558 HydrophobicContact CB-CB 3.94Å; M555-N558 HydrophobicContact CE-CB 4.44Å; M555-N558 PolarHBondContact O-N 2.86Å; N558-E560 VanDerWaalsContact C-N 3.28Å; N558-E560 PolarHBondContact O-N 3.24Å; N558-E560 PolarHBondContact OD1-N 3.16Å; N558-H561 HydrophobicContact CB-CB 4.05Å; N558-H561 PolarHBondContact ND2-CD2 3.03Å; N558-H561 PolarHBondContact ND2-CE1 3.21Å; N558-H561 PolarHBondContact ND2-NE2 2.71Å; N558-H561 PolarHBondContact O-N 3.26Å; N558-L562 PolarHBondContact O-N 2.99Å; N558-L562 VanDerWaalsContact O-N 3.14Å
559P77.4Confident79.3Confident99 Ų9968.5 Ų68.564%0.64333%0.333SS*.Hα-helixtrans-63.6-27.8-178.526.5-35.3000114N557 E563N557-P559 WeakPolarHBondContact O-CD 3.31Å; P559-E563 PolarHBondContact O-N 3.19Å
560E77.1Confident79.9Confident102 Ų10267.7 Ų67.748%0.47733%0.329SS..Hα-helixtrans-68.7-36.9173.4-68.6-159.6-171.500111.4R546 N558 E563 L564R546-E560 IonicContact CZ-OE2 3.65Å; R546-E560 IonicContact NH1-OE2 3.25Å; R546-E560 PolarHBondContact NH1-OE2 3.32Å; R546-E560 IonicContact NH2-OE2 3.05Å; N558-E560 VanDerWaalsContact C-N 3.28Å; N558-E560 PolarHBondContact O-N 3.24Å; N558-E560 PolarHBondContact OD1-N 3.16Å; E560-E563 PolarHBondContact O-N 2.79Å; E560-L564 VanDerWaalsContact O-CD1 3.25Å; E560-L564 WeakPolarHBondContact O-CD1 3.36Å; E560-L564 PolarHBondContact O-N 2.99Å
561H82.6Confident80Confident31 Ų3163.8 Ų63.814%0.14432%0.32CS..Hα-helixtrans-70.5-38.8180-67.2-169.5000111.1L549 D553 F554 M555 N558 L564 L565L549-H561 HydrophobicContact CD2-CB 3.62Å; D553-H561 PolarHBondContact O-CE1 3.48Å; D553-H561 PolarHBondContact O-ND1 2.95Å; F554-H561 HydrophobicContact CD2-CB 4.1Å; F554-H561 HydrophobicContact CE2-CB 4.09Å; M555-H561 PolarHBondContact N-ND1 3.21Å; N558-H561 HydrophobicContact CB-CB 4.05Å; N558-H561 PolarHBondContact ND2-CD2 3.03Å; N558-H561 PolarHBondContact ND2-CE1 3.21Å; N558-H561 PolarHBondContact ND2-NE2 2.71Å; N558-H561 PolarHBondContact O-N 3.26Å; H561-L564 PolarHBondContact O-N 2.76Å; H561-L565 WeakPolarHBondContact O-CG 3.46Å; H561-L565 PolarHBondContact O-N 3.35Å
562L82.1Confident80.1Confident65 Ų6565.4 Ų65.434%0.3433%0.327SS..Hα-helixtrans-63.6-40.1175.5-63.8176.7000112.9F554 N558 L565 R566 L572F554-L562 HydrophobicContact CZ-CD2 4.38Å; N558-L562 PolarHBondContact O-N 2.99Å; N558-L562 VanDerWaalsContact O-N 3.14Å; L562-L565 PolarHBondContact O-N 3.38Å; L562-R566 WeakPolarHBondContact O-CB 3.17Å; L562-R566 PolarHBondContact O-N 3.13Å; L562-L572 HydrophobicContact CD2-CD1 3.79Å
563E81.1Confident80.4Confident59 Ų5962.9 Ų62.928%0.27632%0.317SS..Hα-helixtrans-72-29.9174.8172.162.7-173.300112.3P559 E560 R566 R567P559-E563 PolarHBondContact O-N 3.19Å; E560-E563 PolarHBondContact O-N 2.79Å; E563-R566 IonicContact OE1-NH2 2.78Å; E563-R566 PolarHBondContact OE1-NH2 2.94Å; E563-R566 IonicContact OE2-CZ 2.73Å; E563-R566 IonicContact OE2-NE 2.7Å; E563-R566 PolarHBondContact OE2-NE 2.99Å; E563-R566 IonicContact OE2-NH2 3.18Å; E563-R566 PolarHBondContact OE2-NH2 3.3Å; E563-R567 WeakPolarHBondContact O-CD 3.33Å; E563-R567 VanDerWaalsContact O-CG 3.26Å; E563-R567 WeakPolarHBondContact O-CG 3.35Å; E563-R567 PolarHBondContact O-N 2.9Å; E563-R567 VanDerWaalsContact O-N 3.14Å; E563-R567 IonicContact OE1-CZ 3.84Å; E563-R567 IonicContact OE1-NE 3.23Å; E563-R567 PolarHBondContact OE1-NE 2.86Å; E563-R567 IonicContact OE1-NH2 3.21Å; E563-R567 PolarHBondContact OE1-NH2 3.05Å
564L83.1Confident80.3Confident44 Ų4465.9 Ų65.923%0.2333%0.328CS..Hα-helixtrans-65.5-47.3169.3-98.678.4000111.7L549 E560 H561 R566 R567 M568L549-L564 HydrophobicContact CB-CD2 3.91Å; E560-L564 VanDerWaalsContact O-CD1 3.25Å; E560-L564 WeakPolarHBondContact O-CD1 3.36Å; E560-L564 PolarHBondContact O-N 2.99Å; H561-L564 PolarHBondContact O-N 2.76Å; L564-R566 VanDerWaalsContact C-N 3.32Å; L564-R566 PolarHBondContact O-N 3.48Å; L564-R567 WeakPolarHBondContact O-CB 3.35Å; L564-R567 PolarHBondContact O-N 3.27Å; L564-M568 WeakPolarHBondContact O-CG 3.48Å; L564-M568 PolarHBondContact O-N 3.23Å; L564-M568 VanDerWaalsContact O-N 3.09Å
565L83.4Confident79.8Confident3 Ų367.3 Ų67.32%0.01634%0.337CS..Hα-helixtrans-55.8-47.8174.8-70.7-167.7000111.5F554 H561 L562 R567 M568 G569 V570 L582 F601F554-L565 HydrophobicContact CD2-CD1 4.18Å; F554-L565 HydrophobicContact CE2-CD1 3.41Å; F554-L565 VanDerWaalsContact CE2-CD1 3.41Å; F554-L565 HydrophobicContact CE2-CG 4.01Å; F554-L565 HydrophobicContact CZ-CD1 3.67Å; H561-L565 WeakPolarHBondContact O-CG 3.46Å; H561-L565 PolarHBondContact O-N 3.35Å; L562-L565 PolarHBondContact O-N 3.38Å; L565-R567 VanDerWaalsContact C-N 3.25Å; L565-R567 PolarHBondContact O-N 2.9Å; L565-M568 HydrophobicContact CD2-CE 3.75Å; L565-M568 CarbonylContact O-C 3.46Å; L565-M568 WeakPolarHBondContact O-CA 3.4Å; L565-M568 PolarHBondContact O-N 3.41Å; L565-G569 PolarHBondContact O-N 2.86Å; L565-V570 CarbonylContact C-O 3.54Å; L565-V570 HydrophobicContact CB-CB 4.1Å; L565-V570 HydrophobicContact CB-CG1 4.41Å; L565-V570 HydrophobicContact CD1-CG1 4.27Å; L565-V570 HydrophobicContact CD2-CB 4.29Å; L565-V570 HydrophobicContact CD2-CG1 4.32Å; L565-V570 PolarHBondContact O-N 3.39Å; L565-L582 HydrophobicContact CD1-CD2 4.01Å; L565-F601 HydrophobicContact CD1-CE1 4.2Å; L565-F601 HydrophobicContact CD1-CZ 4.4Å; L565-F601 HydrophobicContact CD2-CD1 3.63Å; L565-F601 HydrophobicContact CD2-CD2 4.1Å; L565-F601 HydrophobicContact CD2-CE1 3.45Å; L565-F601 VanDerWaalsContact CD2-CE1 3.45Å; L565-F601 HydrophobicContact CD2-CE2 3.92Å; L565-F601 HydrophobicContact CD2-CG 3.97Å; L565-F601 HydrophobicContact CD2-CZ 3.62Å; L565-F601 HydrophobicContact CG-CE1 4.49Å
566R83.3Confident79.2Confident161 Ų16173 Ų7361%0.60836%0.359SS*.Hα-helixtrans-59.7-35179.9-161.4177.671.694.54.6112.6L562 E563 L564 G569 V570L562-R566 WeakPolarHBondContact O-CB 3.17Å; L562-R566 PolarHBondContact O-N 3.13Å; E563-R566 IonicContact OE1-NH2 2.78Å; E563-R566 PolarHBondContact OE1-NH2 2.94Å; E563-R566 IonicContact OE2-CZ 2.73Å; E563-R566 IonicContact OE2-NE 2.7Å; E563-R566 PolarHBondContact OE2-NE 2.99Å; E563-R566 IonicContact OE2-NH2 3.18Å; E563-R566 PolarHBondContact OE2-NH2 3.3Å; L564-R566 VanDerWaalsContact C-N 3.32Å; L564-R566 PolarHBondContact O-N 3.48Å; R566-G569 PolarHBondContact O-N 3.25Å; R566-V570 PolarHBondContact N-O 3.17Å
567R83.6Confident78.5Confident128 Ų12875.3 Ų75.348%0.48337%0.366SS..Hα-helixtrans-71.2-31.7174.1-73.3168.8-176.5-142.5-1.3113.4E563 L564 L565 G569 A589 V590E563-R567 WeakPolarHBondContact O-CD 3.33Å; E563-R567 VanDerWaalsContact O-CG 3.26Å; E563-R567 WeakPolarHBondContact O-CG 3.35Å; E563-R567 PolarHBondContact O-N 2.9Å; E563-R567 VanDerWaalsContact O-N 3.14Å; E563-R567 IonicContact OE1-CZ 3.84Å; E563-R567 IonicContact OE1-NE 3.23Å; E563-R567 PolarHBondContact OE1-NE 2.86Å; E563-R567 IonicContact OE1-NH2 3.21Å; E563-R567 PolarHBondContact OE1-NH2 3.05Å; L564-R567 WeakPolarHBondContact O-CB 3.35Å; L564-R567 PolarHBondContact O-N 3.27Å; L565-R567 VanDerWaalsContact C-N 3.25Å; L565-R567 PolarHBondContact O-N 2.9Å; R567-G569 PolarHBondContact O-N 3.38Å; R567-A589 CarbonylContact O-C 3.57Å; R567-A589 VanDerWaalsContact O-CA 3.28Å; R567-A589 WeakPolarHBondContact O-CA 3.35Å; R567-V590 HydrophobicContact CB-CG1 4.41Å; R567-V590 HydrophobicContact CB-CG2 4.12Å; R567-V590 HydrophobicContact CG-CG1 4.24Å; R567-V590 PolarHBondContact O-N 3.35Å
568M85.9Confident77.7Confident12 Ų1270.8 Ų70.86%0.05936%0.357CS..THydrogen-bonded Turntrans-80.35.3173.2-62.4-171.8-55.100113L564 L565 V570 A594 D597 F601L564-M568 WeakPolarHBondContact O-CG 3.48Å; L564-M568 PolarHBondContact O-N 3.23Å; L564-M568 VanDerWaalsContact O-N 3.09Å; L565-M568 HydrophobicContact CD2-CE 3.75Å; L565-M568 CarbonylContact O-C 3.46Å; L565-M568 WeakPolarHBondContact O-CA 3.4Å; L565-M568 PolarHBondContact O-N 3.41Å; M568-V570 PolarHBondContact O-N 3.04Å; M568-A594 WeakPolarHBondContact CA-O 3.44Å; M568-A594 VanDerWaalsContact CB-O 3.26Å; M568-A594 WeakPolarHBondContact CB-O 3.34Å; M568-D597 HydrophobicContact CG-CB 4.48Å; M568-D597 HydrophobicContact SD-CB 3.76Å; M568-F601 HydrophobicContact CE-CB 4.27Å; M568-F601 HydrophobicContact CE-CD2 4.47Å; M568-F601 HydrophobicContact CE-CG 4.35Å
569G84Confident77.1Confident2 Ų277 Ų772%0.02138%0.378CS..THydrogen-bonded Turntrans71.914.4-177.200000113.7L565 R566 R567 H585L565-G569 PolarHBondContact O-N 2.86Å; R566-G569 PolarHBondContact O-N 3.25Å; R567-G569 PolarHBondContact O-N 3.38Å; G569-H585 PolarHBondContact O-N 2.87Å
570V87Confident76.8Confident4 Ų475.8 Ų75.82%0.02437%0.368CS..EExtended strand (participates in β ladder)trans-93.2124.5174.7-179.20000108.9L565 R566 M568 L582 Q584 M602L565-V570 CarbonylContact C-O 3.54Å; L565-V570 HydrophobicContact CB-CB 4.1Å; L565-V570 HydrophobicContact CB-CG1 4.41Å; L565-V570 HydrophobicContact CD1-CG1 4.27Å; L565-V570 HydrophobicContact CD2-CB 4.29Å; L565-V570 HydrophobicContact CD2-CG1 4.32Å; L565-V570 PolarHBondContact O-N 3.39Å; R566-V570 PolarHBondContact N-O 3.17Å; M568-V570 PolarHBondContact O-N 3.04Å; V570-L582 HydrophobicContact CG1-CB 4.39Å; V570-L582 HydrophobicContact CG1-CD2 4.08Å; V570-Q584 HydrophobicContact CG2-CG 4.22Å; V570-M602 HydrophobicContact CG1-SD 3.95Å; V570-M602 HydrophobicContact CG2-CG 4.23Å
571S81.7Confident76.7Confident34 Ų3475.4 Ų75.424%0.23837%0.366CS..EExtended strand (participates in β ladder)trans-109149.7177.367.40000110.8L582 V583S571-L582 WeakPolarHBondContact O-CA 3.34Å; S571-V583 PolarHBondContact N-O 3.4Å; S571-V583 PolarHBondContact O-N 2.82Å; S571-V583 PolarHBondContact OG-O 3.48Å
572L79.9Confident76.7Confident40 Ų4075.4 Ų75.421%0.20937%0.367CS..EExtended strand (participates in β ladder)trans-119.5114.5-176.1-170.7158.6000109.2F554 L562 H574 V580 L582F554-L572 HydrophobicContact CE1-CD1 4.4Å; F554-L572 HydrophobicContact CZ-CD1 3.87Å; L562-L572 HydrophobicContact CD2-CD1 3.79Å; L572-H574 WeakPolarHBondContact CD2-CE1 3.34Å; L572-V580 HydrophobicContact CD1-CG1 3.89Å; L572-V580 HydrophobicContact CD2-CG1 3.55Å; L572-V580 HydrophobicContact CG-CG1 3.51Å; L572-L582 HydrophobicContact CB-CD2 4.03Å; L572-L582 HydrophobicContact CD1-CD2 3.99Å; L572-L582 HydrophobicContact CG-CD2 3.97Å
573I79.1Confident76.7Confident74 Ų7474 Ų7438%0.37936%0.361SS..EExtended strand (participates in β ladder)trans-108.2127.7-176-53.9-178.7000108.5Q581 V583I573-Q581 HydrophobicContact CB-CB 4.49Å; I573-Q581 PolarHBondContact N-O 3.04Å; I573-Q581 PolarHBondContact O-N 3.5Å; I573-V583 HydrophobicContact CD1-CB 4.32Å; I573-V583 HydrophobicContact CD1-CG2 3.73Å; I573-V583 HydrophobicContact CG1-CG2 4.4Å
574H74Confident76.7Confident141 Ų14174.2 Ų74.265%0.65336%0.362SS*.EExtended strand (participates in β ladder)trans-89.9123.8172-65.683.7000109.3L572L572-H574 WeakPolarHBondContact CD2-CE1 3.34Å
575L73Confident76.7Confident66 Ų6675.6 Ų75.635%0.34637%0.367SS..  trans-84.5157.8175.7-65.3172.8000110.5D577 G578 R579 Q581L575-D577 WeakPolarHBondContact CB-OD1 3.47Å; L575-D577 PolarHBondContact O-N 3.41Å; L575-D577 VanDerWaalsContact O-N 3.14Å; L575-G578 PolarHBondContact O-N 2.95Å; L575-G578 VanDerWaalsContact O-N 3.08Å; L575-R579 HydrophobicContact CB-CB 4.48Å; L575-R579 WeakPolarHBondContact CB-O 3.47Å; L575-R579 HydrophobicContact CD1-CB 4.2Å; L575-R579 PolarHBondContact N-O 3.19Å; L575-Q581 HydrophobicContact CD1-CB 4.24Å; L575-Q581 HydrophobicContact CG-CB 4.41Å
576K61.9Low76.4Confident227 Ų22778.1 Ų78.199%0.98739%0.388SS*.THydrogen-bonded Turntrans-67.6-12.2-175.7-69-177.9178179.20114.3
577D57.8Low76.3Confident89 Ų8977 Ų7748%0.47640%0.4SS..THydrogen-bonded Turntrans-94.75.5176.756.913.7000112.7L575 R579L575-D577 WeakPolarHBondContact CB-OD1 3.47Å; L575-D577 PolarHBondContact O-N 3.41Å; L575-D577 VanDerWaalsContact O-N 3.14Å; D577-R579 VanDerWaalsContact C-N 3.32Å; D577-R579 WeakPolarHBondContact OD1-CB 3.5Å; D577-R579 PolarHBondContact OD1-N 3.4Å; D577-R579 IonicContact OD1-NE 2.73Å; D577-R579 IonicContact OD2-CZ 2.94Å; D577-R579 IonicContact OD2-NE 3.75Å; D577-R579 PolarHBondContact OD2-NE 3.08Å; D577-R579 IonicContact OD2-NH2 2.92Å; D577-R579 PolarHBondContact OD2-NH2 2.94Å
578G54Low76.2Confident66 Ų6676.6 Ų76.668%0.6840%0.403SS*.SBendtrans84.4-3.5-17800000114.7L575L575-G578 PolarHBondContact O-N 2.95Å; L575-G578 VanDerWaalsContact O-N 3.08Å
579R66.4Low76.1Confident171 Ų17177 Ų7765%0.64541%0.409SS*.  trans-75.2152.4175.5-64.9-174.1-69.8-179.6-6111.5L575 D577L575-R579 HydrophobicContact CB-CB 4.48Å; L575-R579 WeakPolarHBondContact CB-O 3.47Å; L575-R579 HydrophobicContact CD1-CB 4.2Å; L575-R579 PolarHBondContact N-O 3.19Å; D577-R579 VanDerWaalsContact C-N 3.32Å; D577-R579 WeakPolarHBondContact OD1-CB 3.5Å; D577-R579 PolarHBondContact OD1-N 3.4Å; D577-R579 IonicContact OD1-NE 2.73Å; D577-R579 IonicContact OD2-CZ 2.94Å; D577-R579 IonicContact OD2-NE 3.75Å; D577-R579 PolarHBondContact OD2-NE 3.08Å; D577-R579 IonicContact OD2-NH2 2.92Å; D577-R579 PolarHBondContact OD2-NH2 2.94Å
580V71.7Confident75.9Confident72 Ų7282 Ų8244%0.43644%0.438SS..EExtended strand (participates in β ladder)trans-107126.7177.3173.80000109.2L572L572-V580 HydrophobicContact CD1-CG1 3.89Å; L572-V580 HydrophobicContact CD2-CG1 3.55Å; L572-V580 HydrophobicContact CG-CG1 3.51Å
581Q76.2Confident75.6Confident94 Ų9484.4 Ų84.444%0.43946%0.455SS..EExtended strand (participates in β ladder)trans-112.8123.3175.5-172.5177.320.100109.8I573 L575 V583I573-Q581 HydrophobicContact CB-CB 4.49Å; I573-Q581 PolarHBondContact N-O 3.04Å; I573-Q581 PolarHBondContact O-N 3.5Å; L575-Q581 HydrophobicContact CD1-CB 4.24Å; L575-Q581 HydrophobicContact CG-CB 4.41Å; Q581-V583 HydrophobicContact CG-CG2 4.05Å
582L81.9Confident75.3Confident31 Ų3186.3 Ų86.316%0.16247%0.473CS..EExtended strand (participates in β ladder)trans-89.3133.6171-65167.9000109.5L565 V570 S571 L572 F601 M602 M605L565-L582 HydrophobicContact CD1-CD2 4.01Å; V570-L582 HydrophobicContact CG1-CB 4.39Å; V570-L582 HydrophobicContact CG1-CD2 4.08Å; S571-L582 WeakPolarHBondContact O-CA 3.34Å; L572-L582 HydrophobicContact CB-CD2 4.03Å; L572-L582 HydrophobicContact CD1-CD2 3.99Å; L572-L582 HydrophobicContact CG-CD2 3.97Å; L582-F601 HydrophobicContact CD1-CE1 3.99Å; L582-M602 HydrophobicContact CB-CE 3.82Å; L582-M602 HydrophobicContact CB-SD 3.55Å; L582-M602 VanDerWaalsContact CB-SD 3.55Å; L582-M602 HydrophobicContact CD1-SD 4.22Å; L582-M602 HydrophobicContact CG-SD 4.49Å; L582-M605 HydrophobicContact CD1-CE 4.16Å; L582-M605 HydrophobicContact CD1-CG 4.03Å
583V81.3Confident75.1Confident36 Ų3688.7 Ų88.722%0.21849%0.489CS..EExtended strand (participates in β ladder)trans-133.5122-179.6-178.40000109.8S571 I573 Q581S571-V583 PolarHBondContact N-O 3.4Å; S571-V583 PolarHBondContact O-N 2.82Å; S571-V583 PolarHBondContact OG-O 3.48Å; I573-V583 HydrophobicContact CD1-CB 4.32Å; I573-V583 HydrophobicContact CD1-CG2 3.73Å; I573-V583 HydrophobicContact CG1-CG2 4.4Å; Q581-V583 HydrophobicContact CG-CG2 4.05Å
584Q81.6Confident75Confident64 Ų6485.8 Ų85.830%0.29948%0.476SS..EExtended strand (participates in β ladder)trans-88.3133.6179.2-160.5-146.84.100111.7V570 A595 M602V570-Q584 HydrophobicContact CG2-CG 4.22Å; Q584-A595 PolarHBondContact NE2-O 2.99Å; Q584-M602 HydrophobicContact CB-CG 4.37Å
585H82.9Confident75.2Confident73 Ų7379.7 Ų79.734%0.33845%0.451SS..  trans-129.788.4171.1-63.8-40.2000108.7G569 T587 Q588G569-H585 PolarHBondContact O-N 2.87Å; H585-T587 PolarHBondContact O-N 3.12Å; H585-Q588 HydrophobicContact CB-CB 4.15Å; H585-Q588 HydrophobicContact CB-CG 3.79Å; H585-Q588 PolarHBondContact CD2-NE2 2.59Å; H585-Q588 WeakPolarHBondContact O-CB 3.47Å; H585-Q588 PolarHBondContact O-N 3.29Å
586A77.5Confident75.5Confident55 Ų5582.1 Ų82.146%0.45546%0.46SS..G310 helixtrans-54.8-28.3-177.200000114Q588 A589 A595A586-Q588 PolarHBondContact O-N 3Å; A586-A589 PolarHBondContact O-N 2.98Å; A586-A595 HydrophobicContact CB-CB 4.11Å
587T80.4Confident76.4Confident138 Ų13873 Ų7385%0.84742%0.422SS*.G310 helixtrans-72.7-9175.151.30000114.8H585H585-T587 PolarHBondContact O-N 3.12Å
588Q81.4Confident77.6Confident120 Ų12068.8 Ų68.856%0.56140%0.4SS*.G310 helixtrans-102.3-5.4177.3-60.1-179.68.900112.8H585 A586H585-Q588 HydrophobicContact CB-CB 4.15Å; H585-Q588 HydrophobicContact CB-CG 3.79Å; H585-Q588 PolarHBondContact CD2-NE2 2.59Å; H585-Q588 WeakPolarHBondContact O-CB 3.47Å; H585-Q588 PolarHBondContact O-N 3.29Å; A586-Q588 PolarHBondContact O-N 3Å
589A83.8Confident78.8Confident20 Ų2068.3 Ų68.317%0.16538%0.383CS..SBendtrans-71.5152.1175.900000111.9R567 A586 S591 A594 A595R567-A589 CarbonylContact O-C 3.57Å; R567-A589 VanDerWaalsContact O-CA 3.28Å; R567-A589 WeakPolarHBondContact O-CA 3.35Å; A586-A589 PolarHBondContact O-N 2.98Å; A589-S591 VanDerWaalsContact C-N 3.29Å; A589-S591 PolarHBondContact O-N 3.47Å; A589-A594 HydrophobicContact CB-CB 4.4Å; A589-A595 HydrophobicContact CB-CB 3.76Å
590V81.2Confident79.4Confident107 Ų10765.6 Ų65.665%0.64837%0.373SS*.SBendtrans-76.2-12.7-178.4-64.10000114.3R567 A594R567-V590 HydrophobicContact CB-CG1 4.41Å; R567-V590 HydrophobicContact CB-CG2 4.12Å; R567-V590 HydrophobicContact CG-CG1 4.24Å; R567-V590 PolarHBondContact O-N 3.35Å; V590-A594 HydrophobicContact CG2-CB 4.05Å
591S80.8Confident80Confident54 Ų5462.2 Ų62.238%0.37835%0.353SS..SBendtrans-160166.1172.772.80000110.7A589 V593 A594 A595A589-S591 VanDerWaalsContact C-N 3.29Å; A589-S591 PolarHBondContact O-N 3.47Å; S591-V593 VanDerWaalsContact C-N 3.31Å; S591-V593 PolarHBondContact O-N 3.02Å; S591-A594 PolarHBondContact O-N 2.98Å; S591-A594 WeakPolarHBondContact OG-CB 3.5Å; S591-A594 PolarHBondContact OG-N 3.26Å; S591-A595 PolarHBondContact O-N 3.23Å
592A74.3Confident80.3Confident75 Ų7559.5 Ų59.562%0.6234%0.34SS*.Hα-helixtrans-59.1-41.9173.400000112.2A594 A595 E596A592-A594 VanDerWaalsContact C-N 3.33Å; A592-A594 PolarHBondContact O-N 2.97Å; A592-A595 WeakPolarHBondContact O-CB 3.09Å; A592-A595 PolarHBondContact O-N 3.01Å; A592-A595 VanDerWaalsContact O-N 3.1Å; A592-E596 PolarHBondContact O-N 2.75Å
593V75.2Confident80.2Confident90 Ų9063.5 Ų63.555%0.54536%0.358SS..Hα-helixtrans-62.5-40.5176.3-175.70000111.3S591 A595 E596 D597S591-V593 VanDerWaalsContact C-N 3.31Å; S591-V593 PolarHBondContact O-N 3.02Å; V593-A595 VanDerWaalsContact C-N 3.31Å; V593-A595 PolarHBondContact O-N 2.89Å; V593-E596 PolarHBondContact O-N 3.19Å; V593-D597 PolarHBondContact O-N 3.14Å
594A77.3Confident80.1Confident13 Ų1364.1 Ų64.111%0.10736%0.359CS..Hα-helixtrans-66.9-32.3175.300000112.2M568 A589 V590 S591 A592 G598M568-A594 WeakPolarHBondContact CA-O 3.44Å; M568-A594 VanDerWaalsContact CB-O 3.26Å; M568-A594 WeakPolarHBondContact CB-O 3.34Å; A589-A594 HydrophobicContact CB-CB 4.4Å; V590-A594 HydrophobicContact CG2-CB 4.05Å; S591-A594 PolarHBondContact O-N 2.98Å; S591-A594 WeakPolarHBondContact OG-CB 3.5Å; S591-A594 PolarHBondContact OG-N 3.26Å; A592-A594 VanDerWaalsContact C-N 3.33Å; A592-A594 PolarHBondContact O-N 2.97Å; A594-G598 PolarHBondContact O-N 3.4Å
595A78.8Confident79.8Confident13 Ų1363.8 Ų63.811%0.10736%0.358CS..Hα-helixtrans-67.4-40.5172.600000112Q584 A586 A589 S591 A592 V593 G598 V599Q584-A595 PolarHBondContact NE2-O 2.99Å; A586-A595 HydrophobicContact CB-CB 4.11Å; A589-A595 HydrophobicContact CB-CB 3.76Å; S591-A595 PolarHBondContact O-N 3.23Å; A592-A595 WeakPolarHBondContact O-CB 3.09Å; A592-A595 PolarHBondContact O-N 3.01Å; A592-A595 VanDerWaalsContact O-N 3.1Å; V593-A595 VanDerWaalsContact C-N 3.31Å; V593-A595 PolarHBondContact O-N 2.89Å; A595-G598 CarbonylContact O-C 3.57Å; A595-G598 WeakPolarHBondContact O-CA 3.43Å; A595-G598 PolarHBondContact O-N 3.09Å; A595-V599 PolarHBondContact O-N 3.39Å
596E78.5Confident79.2Confident117 Ų11766.7 Ų66.755%0.54737%0.373SS..Hα-helixtrans-64.1-45.3174.9-72175.1-169.700112.3A592 V593 G598 V599 R600A592-E596 PolarHBondContact O-N 2.75Å; V593-E596 PolarHBondContact O-N 3.19Å; E596-G598 PolarHBondContact O-N 2.83Å; E596-V599 WeakPolarHBondContact O-CB 3.46Å; E596-V599 PolarHBondContact O-N 3.17Å; E596-V599 VanDerWaalsContact O-N 3.1Å; E596-R600 PolarHBondContact O-N 3.29Å
597D81.1Confident78.9Confident36 Ų3670 Ų7019%0.19338%0.379CS..Hα-helixtrans-61.3-33.5172.7-73.2-22.3000111.2P548 M568 V593 R600 F601P548-D597 HydrophobicContact CB-CB 4.28Å; M568-D597 HydrophobicContact CG-CB 4.48Å; M568-D597 HydrophobicContact SD-CB 3.76Å; V593-D597 PolarHBondContact O-N 3.14Å; D597-R600 PolarHBondContact O-N 2.97Å; D597-R600 IonicContact OD1-CZ 2.73Å; D597-R600 IonicContact OD1-NH1 3.93Å; D597-R600 PolarHBondContact OD1-NH1 2.97Å; D597-R600 IonicContact OD1-NH2 2.72Å; D597-F601 WeakPolarHBondContact O-CB 3.46Å; D597-F601 PolarHBondContact O-N 3.41Å
598G82.4Confident78.4Confident0 Ų065.6 Ų65.60%035%0.35CS..Hα-helixtrans-66.1-35.6171.400000114.6A594 A595 E596 M602A594-G598 PolarHBondContact O-N 3.4Å; A595-G598 CarbonylContact O-C 3.57Å; A595-G598 WeakPolarHBondContact O-CA 3.43Å; A595-G598 PolarHBondContact O-N 3.09Å; E596-G598 PolarHBondContact O-N 2.83Å; G598-M602 WeakPolarHBondContact O-CG 3.49Å; G598-M602 PolarHBondContact O-N 3.2Å
599V80.8Confident77.4Confident56 Ų5663.1 Ų63.134%0.33935%0.346SS..Hα-helixtrans-64.7-48170179.90000109.7A595 E596 F601 M602 Q603A595-V599 PolarHBondContact O-N 3.39Å; E596-V599 WeakPolarHBondContact O-CB 3.46Å; E596-V599 PolarHBondContact O-N 3.17Å; E596-V599 VanDerWaalsContact O-N 3.1Å; V599-F601 VanDerWaalsContact C-N 3.34Å; V599-F601 PolarHBondContact O-N 3.39Å; V599-M602 WeakPolarHBondContact O-CB 3.26Å; V599-M602 PolarHBondContact O-N 3.19Å; V599-M602 VanDerWaalsContact O-N 3.12Å; V599-Q603 HydrophobicContact CG1-CG 4.38Å; V599-Q603 WeakPolarHBondContact O-CG 3.43Å; V599-Q603 PolarHBondContact O-N 3.38Å
600R78.8Confident76.2Confident113 Ų11364.9 Ų64.943%0.42636%0.357SS..Hα-helixtrans-61.6-42.5-177.6-164.2-179.2-54.4109.311.1111.8E596 D597 M602 Q603 E604E596-R600 PolarHBondContact O-N 3.29Å; D597-R600 PolarHBondContact O-N 2.97Å; D597-R600 IonicContact OD1-CZ 2.73Å; D597-R600 IonicContact OD1-NH1 3.93Å; D597-R600 PolarHBondContact OD1-NH1 2.97Å; D597-R600 IonicContact OD1-NH2 2.72Å; R600-M602 VanDerWaalsContact C-N 3.32Å; R600-M602 PolarHBondContact O-N 2.99Å; R600-Q603 PolarHBondContact O-N 3.1Å; R600-E604 WeakPolarHBondContact O-CG 3.26Å; R600-E604 PolarHBondContact O-N 2.81Å
601F84.9Confident74.9Confident2 Ų265 Ų651%0.00935%0.351CS..Hα-helixtrans-57.1-44.1173.9-178.9-90000112.3L549 A551 F554 L565 M568 L582 D597 V599 M605L549-F601 HydrophobicContact CG-CE2 4.46Å; L549-F601 WeakPolarHBondContact O-CD2 3.49Å; A551-F601 HydrophobicContact CB-CE2 4.32Å; F554-F601 HydrophobicContact CB-CE2 3.94Å; F554-F601 HydrophobicContact CB-CZ 3.83Å; F554-F601 HydrophobicContact CD1-CZ 4.18Å; F554-F601 HydrophobicContact CD2-CE2 4.32Å; F554-F601 AromaticContact CD2-CZ 3.87Å; F554-F601 HydrophobicContact CD2-CZ 3.87Å; F554-F601 HydrophobicContact CG-CE2 4.21Å; F554-F601 AromaticContact CG-CZ 3.68Å; F554-F601 HydrophobicContact CG-CZ 3.68Å; L565-F601 HydrophobicContact CD1-CE1 4.2Å; L565-F601 HydrophobicContact CD1-CZ 4.4Å; L565-F601 HydrophobicContact CD2-CD1 3.63Å; L565-F601 HydrophobicContact CD2-CD2 4.1Å; L565-F601 HydrophobicContact CD2-CE1 3.45Å; L565-F601 VanDerWaalsContact CD2-CE1 3.45Å; L565-F601 HydrophobicContact CD2-CE2 3.92Å; L565-F601 HydrophobicContact CD2-CG 3.97Å; L565-F601 HydrophobicContact CD2-CZ 3.62Å; L565-F601 HydrophobicContact CG-CE1 4.49Å; M568-F601 HydrophobicContact CE-CB 4.27Å; M568-F601 HydrophobicContact CE-CD2 4.47Å; M568-F601 HydrophobicContact CE-CG 4.35Å; L582-F601 HydrophobicContact CD1-CE1 3.99Å; D597-F601 WeakPolarHBondContact O-CB 3.46Å; D597-F601 PolarHBondContact O-N 3.41Å; V599-F601 VanDerWaalsContact C-N 3.34Å; V599-F601 PolarHBondContact O-N 3.39Å; F601-M605 HydrophobicContact CD1-CG 4.11Å; F601-M605 HydrophobicContact CE1-CG 3.59Å; F601-M605 HydrophobicContact CE1-SD 4.33Å; F601-M605 HydrophobicContact CZ-CG 3.84Å; F601-M605 HydrophobicContact CZ-SD 4.04Å; F601-M605 WeakPolarHBondContact O-CB 3.2Å; F601-M605 WeakPolarHBondContact O-CG 3.28Å; F601-M605 PolarHBondContact O-N 3.08Å
602M81.5Confident73.5Confident37 Ų3769.8 Ų69.818%0.18237%0.367CS..Hα-helixtrans-65.3-38.5177-70.8-65.3-60.300112.3V570 L582 Q584 G598 V599 R600 M605 M606V570-M602 HydrophobicContact CG1-SD 3.95Å; V570-M602 HydrophobicContact CG2-CG 4.23Å; L582-M602 HydrophobicContact CB-CE 3.82Å; L582-M602 HydrophobicContact CB-SD 3.55Å; L582-M602 VanDerWaalsContact CB-SD 3.55Å; L582-M602 HydrophobicContact CD1-SD 4.22Å; L582-M602 HydrophobicContact CG-SD 4.49Å; Q584-M602 HydrophobicContact CB-CG 4.37Å; G598-M602 WeakPolarHBondContact O-CG 3.49Å; G598-M602 PolarHBondContact O-N 3.2Å; V599-M602 WeakPolarHBondContact O-CB 3.26Å; V599-M602 PolarHBondContact O-N 3.19Å; V599-M602 VanDerWaalsContact O-N 3.12Å; R600-M602 VanDerWaalsContact C-N 3.32Å; R600-M602 PolarHBondContact O-N 2.99Å; M602-M605 PolarHBondContact O-N 2.96Å; M602-M606 WeakPolarHBondContact O-CG 3.39Å; M602-M606 PolarHBondContact O-N 2.91Å
603Q79.1Confident72.2Confident114 Ų11472.2 Ų72.253%0.53337%0.366SS..Hα-helixtrans-65.5-48.2175.9-70.8175.9-46.500111.7V599 R600 M605 M606 E607V599-Q603 HydrophobicContact CG1-CG 4.38Å; V599-Q603 WeakPolarHBondContact O-CG 3.43Å; V599-Q603 PolarHBondContact O-N 3.38Å; R600-Q603 PolarHBondContact O-N 3.1Å; Q603-M605 VanDerWaalsContact C-N 3.31Å; Q603-M605 PolarHBondContact O-N 3.47Å; Q603-M606 PolarHBondContact O-N 3.07Å; Q603-M606 VanDerWaalsContact O-N 3.09Å; Q603-E607 PolarHBondContact O-N 2.93Å
604E79.3Confident70.6Confident50 Ų5076.4 Ų76.423%0.23438%0.376CS..Hα-helixtrans-59.6-39.7175.7-68.3178.1-174.700111.8R550 A551 R600 M606 E607 L608R550-E604 WeakPolarHBondContact CA-OE2 3.01Å; R550-E604 WeakPolarHBondContact CB-OE2 3.44Å; A551-E604 HydrophobicContact CB-CB 3.41Å; A551-E604 VanDerWaalsContact CB-CB 3.41Å; A551-E604 PolarHBondContact N-OE2 2.87Å; R600-E604 WeakPolarHBondContact O-CG 3.26Å; R600-E604 PolarHBondContact O-N 2.81Å; E604-M606 VanDerWaalsContact C-N 3.34Å; E604-M606 PolarHBondContact O-N 3.14Å; E604-E607 PolarHBondContact O-N 2.88Å; E604-L608 WeakPolarHBondContact O-CB 3.5Å; E604-L608 VanDerWaalsContact O-CG 3.28Å; E604-L608 WeakPolarHBondContact O-CG 3.45Å; E604-L608 PolarHBondContact O-N 3.12Å
605M76Confident68.9Low56 Ų5683.3 Ų83.328%0.27641%0.406SS..Hα-helixtrans-62.8-37.9174.1-77.2-64.4-52.300112.6A551 L582 F601 M602 Q603 S609A551-M605 HydrophobicContact CB-CB 4.37Å; A551-M605 HydrophobicContact CB-CG 3.67Å; A551-M605 HydrophobicContact CB-SD 3.65Å; L582-M605 HydrophobicContact CD1-CE 4.16Å; L582-M605 HydrophobicContact CD1-CG 4.03Å; F601-M605 HydrophobicContact CD1-CG 4.11Å; F601-M605 HydrophobicContact CE1-CG 3.59Å; F601-M605 HydrophobicContact CE1-SD 4.33Å; F601-M605 HydrophobicContact CZ-CG 3.84Å; F601-M605 HydrophobicContact CZ-SD 4.04Å; F601-M605 WeakPolarHBondContact O-CB 3.2Å; F601-M605 WeakPolarHBondContact O-CG 3.28Å; F601-M605 PolarHBondContact O-N 3.08Å; M602-M605 PolarHBondContact O-N 2.96Å; Q603-M605 VanDerWaalsContact C-N 3.31Å; Q603-M605 PolarHBondContact O-N 3.47Å; M605-S609 WeakPolarHBondContact O-CB 3.41Å; M605-S609 PolarHBondContact O-N 2.8Å; M605-S609 VanDerWaalsContact O-N 3.08Å
606M71.1Confident67.7Low134 Ų13487 Ų8766%0.6642%0.421SS*.Hα-helixtrans-71-40.1176.3-73.417562.300112.1M602 Q603 E604 S609 S610M602-M606 WeakPolarHBondContact O-CG 3.39Å; M602-M606 PolarHBondContact O-N 2.91Å; Q603-M606 PolarHBondContact O-N 3.07Å; Q603-M606 VanDerWaalsContact O-N 3.09Å; E604-M606 VanDerWaalsContact C-N 3.34Å; E604-M606 PolarHBondContact O-N 3.14Å; M606-S609 PolarHBondContact O-N 3.46Å; M606-S610 WeakPolarHBondContact O-CB 3.37Å; M606-S610 PolarHBondContact O-N 3.22Å
607E70.9Confident66.8Low124 Ų12485.2 Ų85.258%0.57942%0.415SS*.Hα-helixtrans-64.2-44.3175.4-73-173.716300111.7Q603 E604 S609 S610 Q611Q603-E607 PolarHBondContact O-N 2.93Å; E604-E607 PolarHBondContact O-N 2.88Å; E607-S609 PolarHBondContact O-N 3.37Å; E607-S610 PolarHBondContact O-N 3.04Å; E607-S610 VanDerWaalsContact O-N 3.13Å; E607-Q611 WeakPolarHBondContact O-CB 3.49Å; E607-Q611 VanDerWaalsContact O-CG 3.32Å; E607-Q611 WeakPolarHBondContact O-CG 3.41Å; E607-Q611 PolarHBondContact O-N 2.85Å
608L70.4Confident66.2Low47 Ų4786.1 Ų86.125%0.24642%0.423CS..Hα-helixtrans-61.8-42.9175-70.6168.1000111.9A551 Q552 E604 S610 Q611 Q612A551-L608 HydrophobicContact CB-CD1 3.66Å; Q552-L608 HydrophobicContact CG-CD1 3.84Å; Q552-L608 HydrophobicContact CG-CD2 4.04Å; Q552-L608 HydrophobicContact CG-CG 4.5Å; E604-L608 WeakPolarHBondContact O-CB 3.5Å; E604-L608 VanDerWaalsContact O-CG 3.28Å; E604-L608 WeakPolarHBondContact O-CG 3.45Å; E604-L608 PolarHBondContact O-N 3.12Å; L608-S610 VanDerWaalsContact C-N 3.25Å; L608-S610 PolarHBondContact O-N 3.48Å; L608-Q611 PolarHBondContact O-N 3.17Å; L608-Q612 WeakPolarHBondContact O-CG 3.4Å; L608-Q612 PolarHBondContact O-N 3.35Å
609S60.5Low66.1Low68 Ų6889.3 Ų89.348%0.47644%0.444SS..Hα-helixtrans-62.8-30.2174.5-178.10000113M605 M606 E607 Q613M605-S609 WeakPolarHBondContact O-CB 3.41Å; M605-S609 PolarHBondContact O-N 2.8Å; M605-S609 VanDerWaalsContact O-N 3.08Å; M606-S609 PolarHBondContact O-N 3.46Å; E607-S609 PolarHBondContact O-N 3.37Å; S609-Q613 WeakPolarHBondContact O-CG 3.2Å
610S56.7Low66.5Low57 Ų5787.3 Ų87.340%0.39943%0.43SS..Hα-helixtrans-82.5-34.1176.4-176.20000112.4M606 E607 L608 Q613 K614M606-S610 WeakPolarHBondContact O-CB 3.37Å; M606-S610 PolarHBondContact O-N 3.22Å; E607-S610 PolarHBondContact O-N 3.04Å; E607-S610 VanDerWaalsContact O-N 3.13Å; L608-S610 VanDerWaalsContact C-N 3.25Å; L608-S610 PolarHBondContact O-N 3.48Å; S610-Q613 WeakPolarHBondContact O-CB 3.5Å; S610-Q613 PolarHBondContact O-N 2.8Å; S610-Q613 VanDerWaalsContact O-N 3.14Å; S610-K614 PolarHBondContact O-N 2.83Å
611Q54.1Low67Low108 Ų10882.2 Ų82.251%0.50541%0.412SS..Hα-helixtrans-66.4-41174.2-73.7169.86.700111.2E607 L608 Q613 K614 E615E607-Q611 WeakPolarHBondContact O-CB 3.49Å; E607-Q611 VanDerWaalsContact O-CG 3.32Å; E607-Q611 WeakPolarHBondContact O-CG 3.41Å; E607-Q611 PolarHBondContact O-N 2.85Å; L608-Q611 PolarHBondContact O-N 3.17Å; Q611-Q613 PolarHBondContact O-N 3.04Å; Q611-K614 PolarHBondContact O-N 2.91Å; Q611-E615 PolarHBondContact O-N 2.82Å
612Q51.3Low67.4Low155 Ų15582.1 Ų82.172%0.72441%0.412SS*.THydrogen-bonded Turntrans-63.4-17.6171.4-73.6-175.3-23.300114L608L608-Q612 WeakPolarHBondContact O-CG 3.4Å; L608-Q612 PolarHBondContact O-N 3.35Å
613Q47.6Very low67.9Low127 Ų12780.7 Ų80.759%0.59341%0.405SS*.THydrogen-bonded Turntrans-88-11.1170.7-72.1177.4-29.100113.3S609 S610 Q611S609-Q613 WeakPolarHBondContact O-CG 3.2Å; S610-Q613 WeakPolarHBondContact O-CB 3.5Å; S610-Q613 PolarHBondContact O-N 2.8Å; S610-Q613 VanDerWaalsContact O-N 3.14Å; Q611-Q613 PolarHBondContact O-N 3.04Å
614K41.6Very low68.5Low177 Ų17775.3 Ų75.377%0.7738%0.38SS*.THydrogen-bonded Turntrans-92.6-17.8177.4-76-168.4171.2-167.70114.3S610 Q611 Q616S610-K614 PolarHBondContact O-N 2.83Å; Q611-K614 PolarHBondContact O-N 2.91Å; K614-Q616 PolarHBondContact O-N 2.99Å; K614-Q616 VanDerWaalsContact O-N 3.12Å
615E42.5Very low69Low158 Ų15874.4 Ų74.474%0.73838%0.377SS*.  trans-80.625.4172.6-62.7-175.8144.700112.8Q611 L617 Q722Q611-E615 PolarHBondContact O-N 2.82Å; E615-L617 PolarHBondContact O-N 3.38Å; E615-Q722 PolarHBondContact O-NE2 3.38Å; E615-Q722 VanDerWaalsContact O-NE2 3.15Å
616Q53.8Low69.5Low90 Ų9072.4 Ų72.442%0.42137%0.369SS..  trans-82.396.4175.3-66.4-150.6-57.200111.2K614 L720K614-Q616 PolarHBondContact O-N 2.99Å; K614-Q616 VanDerWaalsContact O-N 3.12Å; Q616-L720 PolarHBondContact NE2-O 3.26Å
617L57.8Low69.9Low80 Ų8072 Ų7242%0.41937%0.366SS..  trans-38.1135.3159.6-67.5169.7000110.5E615 P639E615-L617 PolarHBondContact O-N 3.38Å; L617-P639 HydrophobicContact CB-CG 3.71Å; L617-P639 HydrophobicContact CD1-CG 4.28Å
618P68.4Low70.3Confident55 Ų5568.2 Ų68.236%0.35735%0.352SS..  trans-63.4156.4-172.422.3-30.9000112.9
619P81.1Confident71Confident67 Ų6768 Ų6844%0.43535%0.349SS..  trans-49.1146172.317.4-30.2000111.9T636 L720P619-T636 HydrophobicContact CB-CG2 3.87Å; P619-L720 HydrophobicContact CB-CD1 3.68Å; P619-L720 HydrophobicContact CG-CD1 4.21Å
620R88.8Confident71.9Confident15 Ų1568.8 Ų68.86%0.05734%0.344CS..EExtended strand (participates in β ladder)trans-106.3158.8169.9-60.4-67.1-168.7-121.215.3109.2A637 P639 D645 L738 D764R620-A637 PolarHBondContact N-O 2.97Å; R620-A637 PolarHBondContact O-N 3.22Å; R620-P639 HydrophobicContact CG-CB 3.89Å; R620-D645 IonicContact CZ-OD1 3.48Å; R620-D645 IonicContact NH2-OD1 3.41Å; R620-D645 PolarHBondContact NH2-OD1 3.28Å; R620-L738 HydrophobicContact CB-CD1 4.07Å; R620-L738 HydrophobicContact CB-CD2 3.57Å; R620-L738 HydrophobicContact CG-CD2 3.73Å; R620-D764 WeakPolarHBondContact CA-O 3.45Å; R620-D764 WeakPolarHBondContact CD-OD1 3.38Å; R620-D764 IonicContact CZ-OD1 2.83Å; R620-D764 IonicContact NE-OD1 3.1Å; R620-D764 IonicContact NH1-OD1 3.63Å; R620-D764 PolarHBondContact NH1-OD1 3.48Å; R620-D764 IonicContact NH2-OD1 3.41Å
621A89.9Confident73.1Confident6 Ų666.8 Ų66.85%0.0533%0.332CS..EExtended strand (participates in β ladder)trans-108.2141.8-179.900000112.2V634 S763 D764 A766A621-V634 HydrophobicContact CB-CG1 4.29Å; A621-S763 PolarHBondContact N-O 3.47Å; A621-S763 PolarHBondContact O-N 2.85Å; A621-D764 PolarHBondContact N-O 2.77Å; A621-A766 HydrophobicContact CB-CB 4.28Å
622I92.8Very high74.4Confident0 Ų071.6 Ų71.60%035%0.345CS..EExtended strand (participates in β ladder)trans-120.2112.2164.9-59.3177.7000107.6L635 A637 I705 L738 L740 V760 L761 L762I622-L635 HydrophobicContact CB-CB 4.3Å; I622-L635 PolarHBondContact N-O 2.85Å; I622-L635 PolarHBondContact O-N 2.96Å; I622-A637 HydrophobicContact CD1-CB 3.94Å; I622-A637 HydrophobicContact CG1-CB 4.05Å; I622-I705 HydrophobicContact CD1-CD1 3.99Å; I622-I705 HydrophobicContact CD1-CG1 3.93Å; I622-I705 HydrophobicContact CD1-CG2 4.09Å; I622-I705 HydrophobicContact CG2-CD1 4.3Å; I622-L738 HydrophobicContact CD1-CB 4Å; I622-L738 HydrophobicContact CD1-CD1 3.99Å; I622-L738 HydrophobicContact CG1-CD1 3.64Å; I622-L740 HydrophobicContact CD1-CD1 4.07Å; I622-L740 HydrophobicContact CD1-CD2 4.07Å; I622-L740 HydrophobicContact CD1-CG 3.97Å; I622-V760 HydrophobicContact CG2-CB 4.05Å; I622-V760 HydrophobicContact CG2-CG1 4.27Å; I622-V760 HydrophobicContact CG2-CG2 4.38Å; I622-L761 WeakPolarHBondContact CA-O 3.32Å; I622-L762 HydrophobicContact CD1-CD2 4.16Å; I622-L762 HydrophobicContact CG1-CD2 3.87Å; I622-L762 HydrophobicContact CG2-CD2 4.16Å
623Q92.8Very high76Confident7 Ų765.9 Ų65.93%0.03332%0.321CS..EExtended strand (participates in β ladder)trans-103.2130.7177.5-66-176.3-89.200110.6V625 G631 V633 V634 V760 L761 R767Q623-V625 HydrophobicContact CB-CG1 4.4Å; Q623-V625 PolarHBondContact O-N 2.83Å; Q623-G631 PolarHBondContact NE2-O 3.25Å; Q623-G631 VanDerWaalsContact NE2-O 3.12Å; Q623-V633 WeakPolarHBondContact CA-O 3.38Å; Q623-V634 HydrophobicContact CG-CG1 4.32Å; Q623-V634 HydrophobicContact CG-CG2 4.17Å; Q623-V760 CarbonylContact O-C 3.58Å; Q623-V760 WeakPolarHBondContact O-CA 3.13Å; Q623-L761 HydrophobicContact CB-CB 4.47Å; Q623-L761 PolarHBondContact N-O 3.45Å; Q623-L761 PolarHBondContact O-N 2.82Å; Q623-R767 PolarHBondContact NE2-O 3.48Å
624I91.8Very high78.1Confident0 Ų063 Ų630%031%0.312CS..EExtended strand (participates in β ladder)trans-82.3108.7171.9-49.4-178.9000108.6F629 G631 V633 L748 A751 V758 V760I624-F629 HydrophobicContact CB-CB 3.97Å; I624-F629 HydrophobicContact CB-CD2 4.25Å; I624-F629 HydrophobicContact CB-CG 4.26Å; I624-F629 HydrophobicContact CG2-CB 3.98Å; I624-F629 HydrophobicContact CG2-CD2 3.55Å; I624-F629 HydrophobicContact CG2-CE2 4.39Å; I624-F629 HydrophobicContact CG2-CG 4.04Å; I624-F629 WeakPolarHBondContact O-CB 3.3Å; I624-G631 WeakPolarHBondContact O-CA 3.46Å; I624-G631 PolarHBondContact O-N 2.68Å; I624-V633 HydrophobicContact CB-CB 4.42Å; I624-V633 HydrophobicContact CD1-CB 4.28Å; I624-V633 HydrophobicContact CD1-CG1 3.83Å; I624-V633 HydrophobicContact CG1-CB 4.34Å; I624-V633 HydrophobicContact CG1-CG1 4.13Å; I624-V633 PolarHBondContact N-O 2.81Å; I624-L748 HydrophobicContact CD1-CD1 4.16Å; I624-L748 HydrophobicContact CG1-CD1 4.38Å; I624-A751 HydrophobicContact CD1-CB 4.24Å; I624-V758 HydrophobicContact CG2-CG1 3.84Å; I624-V760 HydrophobicContact CG1-CG1 4.27Å
625V89.3Confident80.5Confident31 Ų3154.9 Ų54.919%0.18828%0.277CS..  trans-96-19.5-172-64.20000113.6Q623 F630 R654 E759 L761Q623-V625 HydrophobicContact CB-CG1 4.4Å; Q623-V625 PolarHBondContact O-N 2.83Å; V625-F630 WeakPolarHBondContact O-CA 3.35Å; V625-R654 HydrophobicContact CG2-CG 4.5Å; V625-E759 HydrophobicContact CG2-CB 3.89Å; V625-E759 HydrophobicContact CG2-CG 3.74Å; V625-E759 WeakPolarHBondContact CG2-O 3.18Å; V625-E759 WeakPolarHBondContact CG2-OE2 3.23Å; V625-E759 PolarHBondContact N-O 2.85Å; V625-L761 HydrophobicContact CG1-CB 4Å
626S87.1Confident82.7Confident15 Ų1550 Ų5011%0.10526%0.259CS..SBendtrans-67.3165.5174.360.40000113.2F629 F630 E759S626-F629 PolarHBondContact O-N 3.49Å; S626-F630 PolarHBondContact O-N 3.39Å; S626-E759 PolarHBondContact N-O 2.88Å; S626-E759 PolarHBondContact OG-N 2.94Å
627H78.4Confident84.5Confident126 Ų12645.8 Ų45.858%0.58324%0.238SC*.THydrogen-bonded Turntrans-64.1142.2173.1-174.687.1000110.9F630H627-F630 HydrophobicContact CB-CE1 4.38Å; H627-F630 HydrophobicContact CB-CZ 4.1Å; H627-F630 AromaticContact ND1-CE2 3.32Å; H627-F630 VanDerWaalsContact ND1-CE2 3.32Å; H627-F630 WeakPolarHBondContact ND1-CE2 3.21Å; H627-F630 AromaticContact ND1-CZ 3.26Å; H627-F630 VanDerWaalsContact ND1-CZ 3.26Å; H627-F630 WeakPolarHBondContact ND1-CZ 3.28Å
628P79.8Confident85.9Confident44 Ų4442 Ų4229%0.28622%0.219SC..THydrogen-bonded Turncis-88.71.7-1.336.6-38.2000114.2F630 Y755P628-F630 VanDerWaalsContact O-CD2 3.28Å; P628-F630 WeakPolarHBondContact O-CD2 3.44Å; P628-Y755 HydrophobicContact CG-CE1 4.23Å; P628-Y755 HydrophobicContact CG-CE2 4.36Å
629F84Confident86.9Confident42 Ų4239.6 Ų39.618%0.18420%0.204CC..THydrogen-bonded Turntrans-76.9-38.4-166.1-55.8-70.2000113.7I624 S626 G631 R632 V633 A751 Y755I624-F629 HydrophobicContact CB-CB 3.97Å; I624-F629 HydrophobicContact CB-CD2 4.25Å; I624-F629 HydrophobicContact CB-CG 4.26Å; I624-F629 HydrophobicContact CG2-CB 3.98Å; I624-F629 HydrophobicContact CG2-CD2 3.55Å; I624-F629 HydrophobicContact CG2-CE2 4.39Å; I624-F629 HydrophobicContact CG2-CG 4.04Å; I624-F629 WeakPolarHBondContact O-CB 3.3Å; S626-F629 PolarHBondContact O-N 3.49Å; F629-G631 PolarHBondContact O-N 3.07Å; F629-G631 VanDerWaalsContact O-N 3.07Å; F629-R632 WeakPolarHBondContact O-CB 3.39Å; F629-R632 WeakPolarHBondContact O-CG 3.49Å; F629-R632 PolarHBondContact O-N 3.12Å; F629-V633 HydrophobicContact CB-CB 4.47Å; F629-V633 HydrophobicContact CB-CG2 4.3Å; F629-V633 HydrophobicContact CD1-CB 4.32Å; F629-V633 HydrophobicContact CD1-CG2 3.46Å; F629-V633 VanDerWaalsContact CD1-CG2 3.46Å; F629-V633 HydrophobicContact CE1-CG2 4.12Å; F629-V633 HydrophobicContact CG-CG2 4.16Å; F629-A751 HydrophobicContact CE2-CB 3.79Å; F629-A751 HydrophobicContact CZ-CB 4.14Å; F629-Y755 AromaticContact CE2-CD2 3.82Å; F629-Y755 HydrophobicContact CE2-CD2 3.82Å; F629-Y755 AromaticContact CE2-CE2 3.68Å; F629-Y755 HydrophobicContact CE2-CE2 3.68Å; F629-Y755 HydrophobicContact CZ-CD2 4.35Å; F629-Y755 AromaticContact CZ-CE2 3.79Å; F629-Y755 HydrophobicContact CZ-CE2 3.79Å
630F81.4Confident87.2Confident85 Ų8537.2 Ų37.237%0.37319%0.19SC..THydrogen-bonded Turntrans51.933.2170.2-66.6-59.7000115.5V625 S626 H627 P628 R769V625-F630 WeakPolarHBondContact O-CA 3.35Å; S626-F630 PolarHBondContact O-N 3.39Å; H627-F630 HydrophobicContact CB-CE1 4.38Å; H627-F630 HydrophobicContact CB-CZ 4.1Å; H627-F630 AromaticContact ND1-CE2 3.32Å; H627-F630 VanDerWaalsContact ND1-CE2 3.32Å; H627-F630 WeakPolarHBondContact ND1-CE2 3.21Å; H627-F630 AromaticContact ND1-CZ 3.26Å; H627-F630 VanDerWaalsContact ND1-CZ 3.26Å; H627-F630 WeakPolarHBondContact ND1-CZ 3.28Å; P628-F630 VanDerWaalsContact O-CD2 3.28Å; P628-F630 WeakPolarHBondContact O-CD2 3.44Å; F630-R769 PolarHBondContact O-NE 2.76Å; F630-R769 VanDerWaalsContact O-NE 3.14Å
631G80.3Confident87.1Confident15 Ų1541.8 Ų41.816%0.15521%0.212CC..THydrogen-bonded Turntrans89.1-6.9-178.400000115.4Q623 I624 F629 V633Q623-G631 PolarHBondContact NE2-O 3.25Å; Q623-G631 VanDerWaalsContact NE2-O 3.12Å; I624-G631 WeakPolarHBondContact O-CA 3.46Å; I624-G631 PolarHBondContact O-N 2.68Å; F629-G631 PolarHBondContact O-N 3.07Å; F629-G631 VanDerWaalsContact O-N 3.07Å; G631-V633 VanDerWaalsContact C-N 3.34Å; G631-V633 PolarHBondContact O-N 3.39Å
632R81.8Confident86.8Confident208 Ų20842.2 Ų42.279%0.78521%0.212SC*.  trans-70.3-26.1-179-63.9173.4168.5176.5-3.9114F629F629-R632 WeakPolarHBondContact O-CB 3.39Å; F629-R632 WeakPolarHBondContact O-CG 3.49Å; F629-R632 PolarHBondContact O-N 3.12Å
633V86.1Confident86.5Confident35 Ų3543.4 Ų43.421%0.21223%0.225CC..EExtended strand (participates in β ladder)trans-92.4108.5173.6174.60000107.9Q623 I624 F629 G631 L635 I747Q623-V633 WeakPolarHBondContact CA-O 3.38Å; I624-V633 HydrophobicContact CB-CB 4.42Å; I624-V633 HydrophobicContact CD1-CB 4.28Å; I624-V633 HydrophobicContact CD1-CG1 3.83Å; I624-V633 HydrophobicContact CG1-CB 4.34Å; I624-V633 HydrophobicContact CG1-CG1 4.13Å; I624-V633 PolarHBondContact N-O 2.81Å; F629-V633 HydrophobicContact CB-CB 4.47Å; F629-V633 HydrophobicContact CB-CG2 4.3Å; F629-V633 HydrophobicContact CD1-CB 4.32Å; F629-V633 HydrophobicContact CD1-CG2 3.46Å; F629-V633 VanDerWaalsContact CD1-CG2 3.46Å; F629-V633 HydrophobicContact CE1-CG2 4.12Å; F629-V633 HydrophobicContact CG-CG2 4.16Å; G631-V633 VanDerWaalsContact C-N 3.34Å; G631-V633 PolarHBondContact O-N 3.39Å; V633-L635 HydrophobicContact CG1-CD2 3.95Å; V633-L635 HydrophobicContact CG1-CG 4.22Å; V633-I747 HydrophobicContact CG1-CG2 3.94Å
634V90.7Very high86Confident68 Ų6846.3 Ų46.341%0.41224%0.243SC..EExtended strand (participates in β ladder)trans-106.9126.3174.5-170.40000107.8A621 Q623 A766A621-V634 HydrophobicContact CB-CG1 4.29Å; Q623-V634 HydrophobicContact CG-CG1 4.32Å; Q623-V634 HydrophobicContact CG-CG2 4.17Å; V634-A766 HydrophobicContact CG1-CB 3.73Å; V634-A766 HydrophobicContact CG2-CB 4.15Å
635L91.3Very high85.4Confident5 Ų549 Ų493%0.02626%0.257CS..EExtended strand (participates in β ladder)trans-111.9123.2176.8-54174.5000109I622 V633 A637 L740 E744 I747 L748I622-L635 HydrophobicContact CB-CB 4.3Å; I622-L635 PolarHBondContact N-O 2.85Å; I622-L635 PolarHBondContact O-N 2.96Å; V633-L635 HydrophobicContact CG1-CD2 3.95Å; V633-L635 HydrophobicContact CG1-CG 4.22Å; L635-A637 PolarHBondContact O-N 3.03Å; L635-L740 HydrophobicContact CB-CD2 3.92Å; L635-L740 HydrophobicContact CD1-CD1 4.07Å; L635-E744 HydrophobicContact CD2-CB 4.39Å; L635-I747 HydrophobicContact CD2-CB 4.1Å; L635-I747 HydrophobicContact CD2-CD1 3.87Å; L635-I747 HydrophobicContact CD2-CG2 4.17Å; L635-L748 HydrophobicContact CD1-CB 4.12Å
636T90.3Very high85Confident57 Ų5747.8 Ų47.835%0.3525%0.249SC..EExtended strand (participates in β ladder)trans-73.1123178-49.70000110P619 L720 L740P619-T636 HydrophobicContact CB-CG2 3.87Å; T636-L720 HydrophobicContact CG2-CD1 4.18Å; T636-L720 HydrophobicContact CG2-CD2 4.07Å; T636-L740 WeakPolarHBondContact O-CD2 3.4Å
637A89.9Confident84.3Confident0 Ų049.7 Ų49.70%026%0.263CS..EExtended strand (participates in β ladder)trans-121.9146.7-174.800000113.3R620 I622 L635 L738 F739 L740R620-A637 PolarHBondContact N-O 2.97Å; R620-A637 PolarHBondContact O-N 3.22Å; I622-A637 HydrophobicContact CD1-CB 3.94Å; I622-A637 HydrophobicContact CG1-CB 4.05Å; L635-A637 PolarHBondContact O-N 3.03Å; A637-L738 HydrophobicContact CB-CB 4.1Å; A637-L738 HydrophobicContact CB-CD1 4.23Å; A637-F739 CarbonylContact C-O 3.45Å; A637-F739 WeakPolarHBondContact CA-O 3.37Å; A637-F739 WeakPolarHBondContact CB-O 3.2Å; A637-L740 HydrophobicContact CB-CD2 3.94Å
638G88.8Confident83.9Confident1 Ų151.7 Ų51.71%0.0127%0.27CS..EExtended strand (participates in β ladder)trans-81.8135.7171.200000111.8F721 F739G638-F721 WeakPolarHBondContact CA-O 3.09Å; G638-F739 PolarHBondContact N-O 2.83Å; G638-F739 PolarHBondContact O-N 3.23Å
639P88.9Confident83.3Confident5 Ų551.2 Ų51.23%0.03227%0.268CS..EExtended strand (participates in β ladder)trans-76.5157.1178.628.5-32.5000113.3L617 R620 Q722 M723L617-P639 HydrophobicContact CB-CG 3.71Å; L617-P639 HydrophobicContact CD1-CG 4.28Å; R620-P639 HydrophobicContact CG-CB 3.89Å; P639-Q722 HydrophobicContact CG-CG 4.34Å; P639-Q722 WeakPolarHBondContact O-CA 3.45Å; P639-M723 PolarHBondContact O-N 3.21Å
640A87.7Confident82.2Confident17 Ų1754.3 Ų54.314%0.1430%0.295CS..BIsolated β-bridgetrans-83.1152.1160.400000111.9F642 M723 L737A640-F642 HydrophobicContact CB-CD1 4.35Å; A640-F642 HydrophobicContact CB-CD2 4.28Å; A640-F642 HydrophobicContact CB-CE1 4.21Å; A640-F642 HydrophobicContact CB-CE2 4.13Å; A640-F642 HydrophobicContact CB-CG 4.38Å; A640-F642 HydrophobicContact CB-CZ 4.09Å; A640-F642 VanDerWaalsContact CB-O 3.26Å; A640-F642 WeakPolarHBondContact CB-O 3.44Å; A640-F642 PolarHBondContact O-N 3.07Å; A640-M723 HydrophobicContact CB-CB 4.21Å; A640-M723 HydrophobicContact CB-CE 4.18Å; A640-L737 HydrophobicContact CB-CB 4.17Å; A640-L737 WeakPolarHBondContact CB-O 3.32Å; A640-L737 PolarHBondContact N-O 2.88Å
641Q85.4Confident81.7Confident111 Ų11155 Ų5552%0.51931%0.306SS..SBendtrans-84.38169.2-63179.6-18.600112.6M723Q641-M723 PolarHBondContact N-O 3.29Å
642F85.1Confident81.8Confident15 Ų1554.9 Ų54.97%0.06631%0.305CS..SBendtrans-150162.8-173.957.4-97000110A640 F689 A690 A693 M723 T730 I733 L737A640-F642 HydrophobicContact CB-CD1 4.35Å; A640-F642 HydrophobicContact CB-CD2 4.28Å; A640-F642 HydrophobicContact CB-CE1 4.21Å; A640-F642 HydrophobicContact CB-CE2 4.13Å; A640-F642 HydrophobicContact CB-CG 4.38Å; A640-F642 HydrophobicContact CB-CZ 4.09Å; A640-F642 VanDerWaalsContact CB-O 3.26Å; A640-F642 WeakPolarHBondContact CB-O 3.44Å; A640-F642 PolarHBondContact O-N 3.07Å; F642-F689 HydrophobicContact CE1-CB 4.3Å; F642-F689 HydrophobicContact CZ-CB 3.81Å; F642-A690 HydrophobicContact CD1-CB 4.49Å; F642-A690 HydrophobicContact CE1-CB 4.2Å; F642-A690 HydrophobicContact CE2-CB 4.38Å; F642-A690 HydrophobicContact CZ-CB 4.16Å; F642-A693 HydrophobicContact CE2-CB 3.91Å; F642-M723 HydrophobicContact CE1-CB 4.27Å; F642-M723 VanDerWaalsContact CE1-O 3.22Å; F642-M723 WeakPolarHBondContact CE1-O 3.43Å; F642-M723 HydrophobicContact CZ-CB 4.34Å; F642-T730 HydrophobicContact CB-CG2 4.13Å; F642-T730 HydrophobicContact CG-CG2 4.43Å; F642-I733 HydrophobicContact CD2-CB 4.41Å; F642-I733 HydrophobicContact CD2-CD1 3.82Å; F642-I733 HydrophobicContact CD2-CG2 3.98Å; F642-I733 HydrophobicContact CE2-CD1 4.27Å; F642-I733 HydrophobicContact CG-CD1 4.39Å; F642-L737 HydrophobicContact CE2-CB 4.44Å; F642-L737 HydrophobicContact CE2-CD2 4.02Å; F642-L737 HydrophobicContact CZ-CD2 4.05Å
643G84.8Confident82.1Confident25 Ų2546.4 Ų46.426%0.25828%0.276SS..SBendtrans91.9-174.7-172.700000113.4D645 I733 L735G643-D645 PolarHBondContact O-N 3.38Å; G643-I733 WeakPolarHBondContact CA-O 3.45Å; G643-L735 WeakPolarHBondContact CA-O 3.02Å
644T83.6Confident82.4Confident68 Ų6852.1 Ų52.142%0.41729%0.294SS..  trans-66.1124.1173.9-79.10000110.5L646 T734 L735T644-L646 PolarHBondContact O-N 2.73Å; T644-T734 VanDerWaalsContact CB-O 3.27Å; T644-T734 WeakPolarHBondContact CB-O 3.46Å; T644-T734 PolarHBondContact N-O 2.83Å; T644-T734 PolarHBondContact OG1-O 3.01Å; T644-L735 PolarHBondContact N-O 3.26Å
645D79.3Confident82.4Confident56 Ų5649.2 Ų49.230%0.29928%0.278SS..  trans-76108.6175.6-179.16.3000111.1R620 G643 S647 K648R620-D645 IonicContact CZ-OD1 3.48Å; R620-D645 IonicContact NH2-OD1 3.41Å; R620-D645 PolarHBondContact NH2-OD1 3.28Å; G643-D645 PolarHBondContact O-N 3.38Å; D645-S647 PolarHBondContact O-N 2.98Å; D645-S647 VanDerWaalsContact O-N 3.15Å; D645-S647 PolarHBondContact OD1-N 3.05Å; D645-S647 VanDerWaalsContact OD1-N 3.09Å; D645-S647 PolarHBondContact OD1-OG 2.77Å; D645-S647 PolarHBondContact OD2-OG 2.69Å; D645-K648 HydrophobicContact CB-CG 4.47Å; D645-K648 PolarHBondContact O-N 3.3Å; D645-K648 IonicContact OD2-NZ 2.78Å; D645-K648 PolarHBondContact OD2-NZ 2.78Å
646L81.1Confident82.5Confident5 Ų553 Ų533%0.02629%0.294CS..G310 helixtrans-61.5-21-178.1-66.8175.6000113.9T644 K648 S649 V653 P736 L738 L762T644-L646 PolarHBondContact O-N 2.73Å; L646-K648 PolarHBondContact O-N 2.89Å; L646-S649 PolarHBondContact O-N 2.83Å; L646-V653 HydrophobicContact CD2-CG2 4.29Å; L646-P736 HydrophobicContact CD1-CB 4.28Å; L646-P736 HydrophobicContact CD2-CB 3.79Å; L646-P736 HydrophobicContact CD2-CG 4.15Å; L646-P736 HydrophobicContact CG-CB 3.97Å; L646-L738 HydrophobicContact CD1-CD1 3.95Å; L646-L738 HydrophobicContact CD1-CD2 4.15Å; L646-L738 HydrophobicContact CD1-CG 4.23Å; L646-L762 HydrophobicContact CD1-CB 4.02Å
647S70.9Confident82.7Confident56 Ų5650.7 Ų50.739%0.39228%0.28SS..G310 helixtrans-67-19.3174.568.70000113.3D645 D764D645-S647 PolarHBondContact O-N 2.98Å; D645-S647 VanDerWaalsContact O-N 3.15Å; D645-S647 PolarHBondContact OD1-N 3.05Å; D645-S647 VanDerWaalsContact OD1-N 3.09Å; D645-S647 PolarHBondContact OD1-OG 2.77Å; D645-S647 PolarHBondContact OD2-OG 2.69Å; S647-D764 VanDerWaalsContact CA-OD2 3.28Å; S647-D764 WeakPolarHBondContact CA-OD2 3.49Å; S647-D764 WeakPolarHBondContact CB-OD2 3.46Å
648K69.6Low82.8Confident168 Ų16852 Ų5273%0.7329%0.288SS*.G310 helixtrans-95.20.4178.3-58-174177.780.50113.1D645 L646D645-K648 HydrophobicContact CB-CG 4.47Å; D645-K648 PolarHBondContact O-N 3.3Å; D645-K648 IonicContact OD2-NZ 2.78Å; D645-K648 PolarHBondContact OD2-NZ 2.78Å; L646-K648 PolarHBondContact O-N 2.89Å
649S67.6Low83Confident34 Ų3454.7 Ų54.724%0.23830%0.304CS..  trans-111.7104.4179.1-178.20000111.3L646 T651 G652L646-S649 PolarHBondContact O-N 2.83Å; S649-T651 PolarHBondContact O-N 3.31Å; S649-T651 PolarHBondContact OG-OG1 3.35Å; S649-G652 PolarHBondContact O-N 3.44Å; S649-G652 PolarHBondContact OG-N 2.9Å; S649-G652 VanDerWaalsContact OG-N 3.08Å
650S61.1Low83.2Confident107 Ų10754.5 Ų54.575%0.74830%0.302SS*.SBendtrans-64.1-17.4175.755.30000113.4R767S650-R767 PolarHBondContact O-NH2 2.89Å
651T70.5Confident83.3Confident100 Ų10058.9 Ų58.961%0.61332%0.32SS*.SBendtrans-101.3-20.3178.748.40000114S649 R767S649-T651 PolarHBondContact O-N 3.31Å; S649-T651 PolarHBondContact OG-OG1 3.35Å; T651-R767 PolarHBondContact O-NH1 3.44Å; T651-R767 PolarHBondContact O-NH2 3.16Å
652G83.1Confident83.5Confident12 Ų1255.7 Ų55.712%0.12431%0.309CS..  trans71.9-165.8-174.600000112.5S649 L762S649-G652 PolarHBondContact O-N 3.44Å; S649-G652 PolarHBondContact OG-N 2.9Å; S649-G652 VanDerWaalsContact OG-N 3.08Å; G652-L762 WeakPolarHBondContact CA-O 3.41Å
653V88.7Confident83.8Confident30 Ų3058 Ų5818%0.18232%0.318CS..EExtended strand (participates in β ladder)trans-124.1113.4172175.30000109.7L646 I702 P736 L762L646-V653 HydrophobicContact CD2-CG2 4.29Å; V653-I702 HydrophobicContact CG1-CD1 4.23Å; V653-I702 HydrophobicContact CG1-CG1 4.44Å; V653-P736 HydrophobicContact CB-CG 4.28Å; V653-P736 HydrophobicContact CG2-CG 3.88Å; V653-L762 HydrophobicContact CB-CB 4.47Å; V653-L762 PolarHBondContact N-O 2.85Å; V653-L762 PolarHBondContact O-N 3.33Å
654R91.1Very high83.8Confident155 Ų15559 Ų5959%0.58532%0.321SS*.EExtended strand (participates in β ladder)trans-103.2140.2178.9-178.8176.7172.5174.40.3110V625 E759 V760 L761V625-R654 HydrophobicContact CG2-CG 4.5Å; R654-E759 HydrophobicContact CG-CG 4.34Å; R654-E759 WeakPolarHBondContact CG-OE1 3.16Å; R654-E759 IonicContact CZ-OE1 2.76Å; R654-E759 IonicContact CZ-OE2 2.79Å; R654-E759 IonicContact NE-OE1 2.69Å; R654-E759 PolarHBondContact NE-OE1 3.01Å; R654-E759 IonicContact NE-OE2 2.75Å; R654-E759 PolarHBondContact NE-OE2 3.24Å; R654-E759 IonicContact NH2-OE1 3.4Å; R654-E759 PolarHBondContact NH2-OE1 3.19Å; R654-E759 IonicContact NH2-OE2 3.68Å; R654-E759 PolarHBondContact NH2-OE2 3.49Å; R654-V760 WeakPolarHBondContact CA-O 3.36Å; R654-L761 HydrophobicContact CB-CD1 4.13Å
655G91.3Very high84Confident7 Ų755.8 Ų55.87%0.07230%0.301CS..EExtended strand (participates in β ladder)trans175.8169.7172.900000114.9E759 V760G655-E759 WeakPolarHBondContact O-CA 3.32Å; G655-V760 PolarHBondContact N-O 3.09Å; G655-V760 PolarHBondContact O-N 3.14Å
656F93.5Very high84.3Confident83 Ų8355.2 Ų55.236%0.36430%0.301SS..EExtended strand (participates in β ladder)trans-73.8143.2175.8-65.2-76.9000111.5H678 I679 E757 V758 E759F656-H678 WeakPolarHBondContact O-CB 3.45Å; F656-I679 PolarHBondContact O-N 3.25Å; F656-E757 HydrophobicContact CD1-CB 4.08Å; F656-E757 HydrophobicContact CE1-CB 3.94Å; F656-V758 WeakPolarHBondContact CA-O 3.4Å; F656-E759 HydrophobicContact CD1-CB 3.84Å; F656-E759 HydrophobicContact CD1-CG 4.24Å; F656-E759 HydrophobicContact CE1-CB 3.84Å; F656-E759 HydrophobicContact CE1-CG 4.26Å
657V94.3Very high84.7Confident10 Ų1057.8 Ų57.86%0.06132%0.319CS..EExtended strand (participates in β ladder)trans-95.3121.7-176.9-176.60000110.9I679 L681 L752 V758 V760V657-I679 WeakPolarHBondContact CA-O 3.45Å; V657-I679 HydrophobicContact CG2-CB 4.44Å; V657-L681 HydrophobicContact CG1-CB 3.76Å; V657-L681 HydrophobicContact CG1-CD2 4.17Å; V657-L681 HydrophobicContact CG1-CG 4.41Å; V657-L752 HydrophobicContact CB-CD1 4.48Å; V657-L752 HydrophobicContact CB-CD2 4.38Å; V657-L752 HydrophobicContact CG1-CD1 3.94Å; V657-V758 PolarHBondContact N-O 3.26Å; V657-V760 HydrophobicContact CG2-CB 4.15Å; V657-V760 HydrophobicContact CG2-CG1 3.67Å; V657-V760 HydrophobicContact CG2-CG2 3.42Å; V657-V760 VanDerWaalsContact CG2-CG2 3.42Å
658T93.3Very high85.5Confident27 Ų2761 Ų6117%0.16633%0.328CS..EExtended strand (participates in β ladder)trans-116.9131.4175.6-61.80000110.2A660 Y674 V675 H678 I679 A680 L681T658-A660 PolarHBondContact O-N 3.21Å; T658-Y674 WeakPolarHBondContact CG2-O 3.43Å; T658-Y674 PolarHBondContact OG1-O 3Å; T658-Y674 VanDerWaalsContact OG1-O 3.08Å; T658-V675 HydrophobicContact CG2-CG2 4.01Å; T658-H678 PolarHBondContact OG1-CD2 2.89Å; T658-I679 PolarHBondContact N-O 3.45Å; T658-A680 WeakPolarHBondContact O-CA 3.37Å; T658-L681 PolarHBondContact O-N 3.43Å
659V93.1Very high86.7Confident58 Ų5853.9 Ų53.935%0.35230%0.298SS..EExtended strand (participates in β ladder)trans-69.2121.7171.6-175.30000109.5Y663 N671 L681V659-Y663 HydrophobicContact CG1-CD2 3.62Å; V659-Y663 HydrophobicContact CG1-CE2 4.03Å; V659-Y663 HydrophobicContact CG1-CG 4.38Å; V659-N671 PolarHBondContact O-ND2 2.69Å; V659-L681 HydrophobicContact CG2-CD2 4.39Å
660A91.6Very high87.7Confident0 Ų057.5 Ų57.50%032%0.319CS..  trans-79.6143.8178.500000111.2T658 P662 Y663 I669 V675 A680 L681 L682T658-A660 PolarHBondContact O-N 3.21Å; A660-P662 CarbonylContact O-C 3.48Å; A660-P662 VanDerWaalsContact O-C 3.28Å; A660-Y663 WeakPolarHBondContact O-CA 3.38Å; A660-Y663 PolarHBondContact O-N 2.87Å; A660-Y663 VanDerWaalsContact O-N 3.17Å; A660-I669 HydrophobicContact CB-CD1 4.32Å; A660-I669 HydrophobicContact CB-CG2 4.25Å; A660-V675 HydrophobicContact CB-CG2 4.21Å; A660-A680 HydrophobicContact CB-CB 4.38Å; A660-L681 PolarHBondContact N-O 3.25Å; A660-L682 HydrophobicContact CB-CD2 3.85Å
661E89.9Confident89.2Confident109 Ų10953.4 Ų53.451%0.50929%0.289SS..SBendtrans-111.5129175.7-68.1-171.2152.300110.8I669 T670 N671E661-I669 CarbonylContact O-C 3.42Å; E661-I669 VanDerWaalsContact O-CA 3.23Å; E661-I669 WeakPolarHBondContact O-CA 3.11Å; E661-I669 WeakPolarHBondContact O-CG2 3.23Å; E661-T670 WeakPolarHBondContact CB-OG1 3.46Å; E661-T670 PolarHBondContact O-N 2.76Å; E661-T670 PolarHBondContact O-OG1 3.4Å; E661-N671 HydrophobicContact CB-CB 4.18Å; E661-N671 HydrophobicContact CG-CB 4.35Å; E661-N671 PolarHBondContact N-OD1 3.34Å
662P90.9Very high90Very high45 Ų4550.1 Ų50.129%0.29227%0.272SS..SBendcis-69.6146.8-730.9-35.2000111.7A660 S664 G665 S667A660-P662 CarbonylContact O-C 3.48Å; A660-P662 VanDerWaalsContact O-C 3.28Å; P662-S664 PolarHBondContact O-N 2.62Å; P662-G665 PolarHBondContact O-N 3.12Å; P662-S667 VanDerWaalsContact CG-OG 3.3Å; P662-S667 WeakPolarHBondContact CG-OG 3.45Å
663Y89.9Confident90.3Very high64 Ų6457.8 Ų57.825%0.25130%0.304SS..THydrogen-bonded Turntrans-57.3-21.3-176.2-172.3-140.2000114.3V659 A660 G665 L681 Q683V659-Y663 HydrophobicContact CG1-CD2 3.62Å; V659-Y663 HydrophobicContact CG1-CE2 4.03Å; V659-Y663 HydrophobicContact CG1-CG 4.38Å; A660-Y663 WeakPolarHBondContact O-CA 3.38Å; A660-Y663 PolarHBondContact O-N 2.87Å; A660-Y663 VanDerWaalsContact O-N 3.17Å; Y663-G665 VanDerWaalsContact C-N 3.35Å; Y663-L681 HydrophobicContact CE2-CG 4.5Å; Y663-Q683 HydrophobicContact CD1-CB 3.75Å; Y663-Q683 HydrophobicContact CD1-CG 4.39Å; Y663-Q683 HydrophobicContact CD2-CB 4.44Å; Y663-Q683 HydrophobicContact CE1-CB 3.61Å; Y663-Q683 HydrophobicContact CE1-CG 3.92Å; Y663-Q683 HydrophobicContact CE2-CB 4.31Å; Y663-Q683 HydrophobicContact CG-CB 4.17Å; Y663-Q683 PolarHBondContact O-N 3.43Å
664S86.4Confident90.2Very high45 Ų4564 Ų6432%0.31533%0.325SS..THydrogen-bonded Turntrans-74.5-17.3173.864.70000114.6P662 C666 K692P662-S664 PolarHBondContact O-N 2.62Å; S664-C666 PolarHBondContact O-N 3.23Å; S664-C666 PolarHBondContact O-SG 3.32Å; S664-K692 PolarHBondContact O-NZ 2.88Å
665G85.9Confident90.1Very high0 Ų056.6 Ų56.60%030%0.297CS..  trans61.410.1-177.100000115.6P662 Y663 S667 N695P662-G665 PolarHBondContact O-N 3.12Å; Y663-G665 VanDerWaalsContact C-N 3.35Å; G665-S667 PolarHBondContact O-N 2.96Å; G665-N695 PolarHBondContact O-ND2 3.1Å
666C87Confident90.1Very high44 Ų4462.6 Ų62.630%0.29732%0.323SS..  trans-84.59.4-173.7-57.50000114.3S664 C687S664-C666 PolarHBondContact O-N 3.23Å; S664-C666 PolarHBondContact O-SG 3.32Å; C666-C687 WeakPolarHBondContact CA-SG 3.43Å; C666-C687 HydrophobicContact CB-CB 3.59Å; C666-C687 WeakPolarHBondContact CB-SG 3.48Å; C666-C687 WeakPolarHBondContact SG-CB 3.46Å; C666-C687 CovalentContact SG-SG 2.03Å; C666-C687 PolarHBondContact SG-SG 2.84Å
667S88.8Confident89.9Confident59 Ų5960.6 Ų60.641%0.41333%0.327SS..SBendtrans-146.7178.8174.466.10000109.5P662 G665 N695P662-S667 VanDerWaalsContact CG-OG 3.3Å; P662-S667 WeakPolarHBondContact CG-OG 3.45Å; G665-S667 PolarHBondContact O-N 2.96Å; S667-N695 PolarHBondContact O-ND2 2.88Å
668E88.9Confident89.9Confident125 Ų12563 Ų6358%0.58434%0.337SS*.  trans-55.4140.4170.2-54.6-166.5132.600110.9K698E668-K698 IonicContact OE1-NZ 3.79Å; E668-K698 PolarHBondContact OE1-NZ 3.38Å
669I92.9Very high90Very high17 Ų1761.7 Ų61.79%0.08733%0.329CS..  trans-81.5119.9-173.7-54.7-55.2000109.5A660 E661 N671 V675 N695 I696 A699A660-I669 HydrophobicContact CB-CD1 4.32Å; A660-I669 HydrophobicContact CB-CG2 4.25Å; E661-I669 CarbonylContact O-C 3.42Å; E661-I669 VanDerWaalsContact O-CA 3.23Å; E661-I669 WeakPolarHBondContact O-CA 3.11Å; E661-I669 WeakPolarHBondContact O-CG2 3.23Å; I669-N671 WeakPolarHBondContact CG2-OD1 3.09Å; I669-V675 HydrophobicContact CG2-CG2 4.16Å; I669-N695 HydrophobicContact CD1-CB 4.28Å; I669-N695 HydrophobicContact CG1-CB 4.29Å; I669-I696 HydrophobicContact CD1-CG2 4.16Å; I669-I696 HydrophobicContact CG1-CG2 4.15Å; I669-A699 HydrophobicContact CB-CB 3.93Å; I669-A699 HydrophobicContact CG1-CB 4.13Å; I669-A699 HydrophobicContact CG2-CB 4.25Å
670T89.3Confident90.1Very high111 Ų11158.9 Ų58.968%0.68131%0.312SS*.THydrogen-bonded Turntrans-78.9-27.4-174.550.40000113.3E661E661-T670 WeakPolarHBondContact CB-OG1 3.46Å; E661-T670 PolarHBondContact O-N 2.76Å; E661-T670 PolarHBondContact O-OG1 3.4Å
671N92.2Very high90.2Very high21 Ų2158.9 Ų58.911%0.11231%0.312CS..THydrogen-bonded Turntrans-98.532.7178.572.2-24.1000113.2V659 E661 I669 E673 Y674 V675V659-N671 PolarHBondContact O-ND2 2.69Å; E661-N671 HydrophobicContact CB-CB 4.18Å; E661-N671 HydrophobicContact CG-CB 4.35Å; E661-N671 PolarHBondContact N-OD1 3.34Å; I669-N671 WeakPolarHBondContact CG2-OD1 3.09Å; N671-E673 PolarHBondContact O-N 3.15Å; N671-E673 VanDerWaalsContact O-N 3.09Å; N671-Y674 HydrophobicContact CB-CD2 4.27Å; N671-Y674 PolarHBondContact O-N 3.36Å; N671-V675 PolarHBondContact O-N 3.42Å; N671-V675 WeakPolarHBondContact OD1-CG2 3.32Å
672A87.9Confident90.4Very high31 Ų3153.7 Ų53.726%0.25629%0.288SS..Hα-helixtrans-51.5-36.2-174.100000114.2Y674 V675 Q676 A699A672-Y674 PolarHBondContact O-N 2.68Å; A672-Y674 VanDerWaalsContact O-N 3.17Å; A672-V675 PolarHBondContact O-N 3.33Å; A672-Q676 PolarHBondContact O-N 2.77Å; A672-A699 HydrophobicContact CB-CB 3.92Å
673E89.6Confident90.5Very high172 Ų17254.9 Ų54.980%0.80429%0.29SS*.Hα-helixtrans-58.6-26.1176.7-62.3-178.9168.400113.9N671N671-E673 PolarHBondContact O-N 3.15Å; N671-E673 VanDerWaalsContact O-N 3.09Å
674Y86.5Confident90.4Very high160 Ų16055.9 Ų55.963%0.62729%0.293SS*.Hα-helixtrans-96.9-17.2176.9-61-88000113.3T658 N671 A672T658-Y674 WeakPolarHBondContact CG2-O 3.43Å; T658-Y674 PolarHBondContact OG1-O 3Å; T658-Y674 VanDerWaalsContact OG1-O 3.08Å; N671-Y674 HydrophobicContact CB-CD2 4.27Å; N671-Y674 PolarHBondContact O-N 3.36Å; A672-Y674 PolarHBondContact O-N 2.68Å; A672-Y674 VanDerWaalsContact O-N 3.17Å
675V89.8Confident90.1Very high0 Ų055 Ų550%029%0.292CS..Hα-helixtrans-91.9-23.9179.3171.10000111.2T658 A660 I669 N671 A672 G677 H678 A680 A699 A701T658-V675 HydrophobicContact CG2-CG2 4.01Å; A660-V675 HydrophobicContact CB-CG2 4.21Å; I669-V675 HydrophobicContact CG2-CG2 4.16Å; N671-V675 PolarHBondContact O-N 3.42Å; N671-V675 WeakPolarHBondContact OD1-CG2 3.32Å; A672-V675 PolarHBondContact O-N 3.33Å; V675-G677 PolarHBondContact O-N 2.77Å; V675-H678 PolarHBondContact O-N 3.03Å; V675-A680 HydrophobicContact CG1-CB 4.01Å; V675-A699 HydrophobicContact CB-CB 4.48Å; V675-A699 HydrophobicContact CG1-CB 4.04Å; V675-A701 HydrophobicContact CG1-CB 3.82Å
676Q91Very high89.7Confident133 Ų13365.1 Ų65.162%0.62134%0.338SS*.THydrogen-bonded Turntrans-58.9128.2175.6-173.8172.4-5.900111.2A672 H678 G700A672-Q676 PolarHBondContact O-N 2.77Å; Q676-H678 PolarHBondContact O-N 3.35Å; Q676-H678 PolarHBondContact O-ND1 2.84Å; Q676-G700 WeakPolarHBondContact CA-O 3.47Å
677G88.5Confident89.5Confident42 Ų4263.7 Ų63.743%0.43333%0.329SS..THydrogen-bonded Turntrans73.7-1-176.800000115.3V675 G700 I702V675-G677 PolarHBondContact O-N 2.77Å; G677-G700 PolarHBondContact N-O 3.42Å; G677-I702 WeakPolarHBondContact O-CD1 3.32Å
678H94Very high89.3Confident59 Ų5965.3 Ų65.327%0.27333%0.331SS..SBendtrans-110165.9-175.7-7068.7000111.9F656 T658 V675 Q676 A701 I702F656-H678 WeakPolarHBondContact O-CB 3.45Å; T658-H678 PolarHBondContact OG1-CD2 2.89Å; V675-H678 PolarHBondContact O-N 3.03Å; Q676-H678 PolarHBondContact O-N 3.35Å; Q676-H678 PolarHBondContact O-ND1 2.84Å; H678-A701 WeakPolarHBondContact O-CA 3.33Å; H678-I702 WeakPolarHBondContact O-CG1 3.28Å; H678-I702 PolarHBondContact O-N 3Å
679I95.5Very high89.3Confident0 Ų060.4 Ų60.40%031%0.308CS..EExtended strand (participates in β ladder)trans-87.6116.3170.9-65.8172.3000107.9F656 V657 T658 L681 I702 G703 I705 V760 L762F656-I679 PolarHBondContact O-N 3.25Å; V657-I679 WeakPolarHBondContact CA-O 3.45Å; V657-I679 HydrophobicContact CG2-CB 4.44Å; T658-I679 PolarHBondContact N-O 3.45Å; I679-L681 PolarHBondContact O-N 2.88Å; I679-I702 HydrophobicContact CG1-CD1 4.23Å; I679-I702 HydrophobicContact CG1-CG1 4.03Å; I679-G703 WeakPolarHBondContact CA-O 3.32Å; I679-I705 HydrophobicContact CG2-CD1 3.87Å; I679-I705 HydrophobicContact CG2-CG1 3.9Å; I679-V760 HydrophobicContact CD1-CG2 3.61Å; I679-L762 HydrophobicContact CD1-CD1 4.07Å; I679-L762 HydrophobicContact CD1-CD2 4.33Å; I679-L762 HydrophobicContact CD1-CG 3.95Å; I679-L762 HydrophobicContact CG1-CD1 4.49Å; I679-L762 HydrophobicContact CG2-CD1 4.3Å
680A95.4Very high89Confident0 Ų059.6 Ų59.60%030%0.304CS..EExtended strand (participates in β ladder)trans-79.2120.1-175.300000111.9T658 A660 V675 I696 A701 G703 G704 I705T658-A680 WeakPolarHBondContact O-CA 3.37Å; A660-A680 HydrophobicContact CB-CB 4.38Å; V675-A680 HydrophobicContact CG1-CB 4.01Å; A680-I696 HydrophobicContact CB-CB 3.95Å; A680-I696 HydrophobicContact CB-CD1 3.84Å; A680-I696 HydrophobicContact CB-CG1 4.5Å; A680-I696 HydrophobicContact CB-CG2 3.7Å; A680-A701 HydrophobicContact CB-CB 4.06Å; A680-G703 PolarHBondContact N-O 2.98Å; A680-G704 CarbonylContact O-C 3.52Å; A680-G704 VanDerWaalsContact O-CA 3.24Å; A680-G704 WeakPolarHBondContact O-CA 3.44Å; A680-I705 PolarHBondContact O-N 3.3Å
681L94.8Very high89Confident0 Ų058.5 Ų58.50%029%0.291CS..EExtended strand (participates in β ladder)trans-90.7128.7172.7-166.461.8000110.9V657 T658 V659 A660 Y663 I679 I705 I707 L748 L749 L752V657-L681 HydrophobicContact CG1-CB 3.76Å; V657-L681 HydrophobicContact CG1-CD2 4.17Å; V657-L681 HydrophobicContact CG1-CG 4.41Å; T658-L681 PolarHBondContact O-N 3.43Å; V659-L681 HydrophobicContact CG2-CD2 4.39Å; A660-L681 PolarHBondContact N-O 3.25Å; Y663-L681 HydrophobicContact CE2-CG 4.5Å; I679-L681 PolarHBondContact O-N 2.88Å; L681-I705 HydrophobicContact CD1-CB 3.65Å; L681-I705 HydrophobicContact CD1-CG2 3.63Å; L681-I707 HydrophobicContact CD1-CD1 3.77Å; L681-I707 HydrophobicContact CD1-CG1 4.01Å; L681-I707 HydrophobicContact CD2-CD1 4.15Å; L681-I707 HydrophobicContact CG-CD1 4.2Å; L681-L748 HydrophobicContact CD1-CD2 3.97Å; L681-L748 HydrophobicContact CD2-CD2 4.41Å; L681-L749 HydrophobicContact CD2-CD2 3.61Å; L681-L749 HydrophobicContact CD2-CG 4.34Å; L681-L752 HydrophobicContact CD2-CD1 3.54Å
682L94.1Very high89Confident0 Ų057.5 Ų57.50%029%0.286CS..EExtended strand (participates in β ladder)trans-135.2158.5-170.8-70.9167.5000110.9A660 K692 I696 I705 V706 I707A660-L682 HydrophobicContact CB-CD2 3.85Å; L682-K692 HydrophobicContact CD1-CB 4.1Å; L682-I696 HydrophobicContact CD1-CD1 4.2Å; L682-I696 HydrophobicContact CD1-CG2 3.95Å; L682-I696 HydrophobicContact CD2-CG2 4.34Å; L682-I696 HydrophobicContact CG-CG2 4.45Å; L682-I705 PolarHBondContact N-O 3.47Å; L682-V706 HydrophobicContact CB-CG2 4.24Å; L682-V706 HydrophobicContact CD1-CG2 4.29Å; L682-V706 CarbonylContact O-C 3.53Å; L682-V706 WeakPolarHBondContact O-CA 3.26Å; L682-I707 PolarHBondContact O-N 3.4Å
683Q92.7Very high89.1Confident70 Ų7056 Ų5633%0.32727%0.273SS..EExtended strand (participates in β ladder)trans-100.3151.7166.7-150.5174.710.300111.6Y663 K692 I707 D709Y663-Q683 HydrophobicContact CD1-CB 3.75Å; Y663-Q683 HydrophobicContact CD1-CG 4.39Å; Y663-Q683 HydrophobicContact CD2-CB 4.44Å; Y663-Q683 HydrophobicContact CE1-CB 3.61Å; Y663-Q683 HydrophobicContact CE1-CG 3.92Å; Y663-Q683 HydrophobicContact CE2-CB 4.31Å; Y663-Q683 HydrophobicContact CG-CB 4.17Å; Y663-Q683 PolarHBondContact O-N 3.43Å; Q683-K692 PolarHBondContact O-NZ 3.32Å; Q683-I707 CarbonylContact C-O 3.36Å; Q683-I707 WeakPolarHBondContact CA-O 3.46Å; Q683-D709 HydrophobicContact CG-CB 4.3Å
684R87.9Confident89.2Confident84 Ų8450.2 Ų50.232%0.31724%0.244SC..  trans-56.5154157.7-171.7171.8177-166.7-0.6110F689 V706 I707 D708 D709R684-F689 HydrophobicContact CG-CE1 4.45Å; R684-F689 HydrophobicContact CG-CZ 4.29Å; R684-V706 HydrophobicContact CB-CG1 4.49Å; R684-I707 WeakPolarHBondContact CB-O 3.16Å; R684-I707 PolarHBondContact N-O 2.98Å; R684-D708 WeakPolarHBondContact CD-OD1 3.46Å; R684-D708 IonicContact CZ-OD1 2.67Å; R684-D708 IonicContact NE-OD1 3.6Å; R684-D708 IonicContact NH1-OD1 3.78Å; R684-D708 PolarHBondContact NH1-OD1 2.92Å; R684-D709 HydrophobicContact CB-CB 4.17Å; R684-D709 VanDerWaalsContact CD-OD1 3.23Å; R684-D709 WeakPolarHBondContact CD-OD1 3.27Å; R684-D709 WeakPolarHBondContact CG-OD1 3.34Å; R684-D709 IonicContact NE-OD1 3.89Å
685G80.1Confident89.5Confident28 Ų2843.9 Ų43.929%0.28922%0.221SC..  trans179.4-164.7-177.400000111.6C687G685-C687 VanDerWaalsContact C-N 3.3Å; G685-C687 PolarHBondContact O-N 3.23Å
686Q76.3Confident89.7Confident211 Ų21143.9 Ų43.999%0.98622%0.221SC*.SBendtrans-77-5.7-168-61.7-176.8-4.600115.7
687C82.9Confident89.8Confident15 Ų1540.2 Ų40.210%0.10120%0.204CC..SBendtrans-101.5157.4175.960.40000112.8C666 G685 E691C666-C687 WeakPolarHBondContact CA-SG 3.43Å; C666-C687 HydrophobicContact CB-CB 3.59Å; C666-C687 WeakPolarHBondContact CB-SG 3.48Å; C666-C687 WeakPolarHBondContact SG-CB 3.46Å; C666-C687 CovalentContact SG-SG 2.03Å; C666-C687 PolarHBondContact SG-SG 2.84Å; G685-C687 VanDerWaalsContact C-N 3.3Å; G685-C687 PolarHBondContact O-N 3.23Å; C687-E691 WeakPolarHBondContact CB-OE2 3.28Å
688M85.4Confident89.9Confident92 Ų9245.5 Ų45.545%0.45322%0.215SC..  trans-70.9150.3-178.1-61.6-61.8-76.100112A690 E691 K692 G725 D726M688-A690 VanDerWaalsContact C-N 3.34Å; M688-A690 PolarHBondContact O-N 3.42Å; M688-E691 WeakPolarHBondContact O-CB 3.32Å; M688-E691 PolarHBondContact O-N 2.97Å; M688-K692 PolarHBondContact O-N 2.77Å; M688-G725 VanDerWaalsContact CE-O 3.32Å; M688-G725 WeakPolarHBondContact CE-O 3.21Å; M688-D726 HydrophobicContact CB-CB 3.86Å; M688-D726 HydrophobicContact CG-CB 4.05Å
689F89.1Confident89.8Confident22 Ų2243.1 Ų43.110%0.09621%0.206CC..Hα-helixtrans-63.5-36.5-177.2-59.5-82.3000113.3F642 R684 E691 K692 A693 V706 F721 M723 L737 F739F642-F689 HydrophobicContact CE1-CB 4.3Å; F642-F689 HydrophobicContact CZ-CB 3.81Å; R684-F689 HydrophobicContact CG-CE1 4.45Å; R684-F689 HydrophobicContact CG-CZ 4.29Å; F689-E691 VanDerWaalsContact C-N 3.27Å; F689-E691 PolarHBondContact O-N 3.1Å; F689-K692 HydrophobicContact CD1-CD 4.32Å; F689-K692 WeakPolarHBondContact O-CB 3.49Å; F689-K692 PolarHBondContact O-N 2.94Å; F689-A693 PolarHBondContact O-N 3.21Å; F689-V706 HydrophobicContact CD1-CG1 4.14Å; F689-V706 HydrophobicContact CD1-CG2 4.44Å; F689-V706 HydrophobicContact CE1-CG1 3.93Å; F689-F721 HydrophobicContact CD2-CE1 4.41Å; F689-F721 HydrophobicContact CE1-CE1 4.47Å; F689-F721 AromaticContact CE2-CE1 3.53Å; F689-F721 HydrophobicContact CE2-CE1 3.53Å; F689-F721 AromaticContact CE2-CZ 3.73Å; F689-F721 HydrophobicContact CE2-CZ 3.73Å; F689-F721 AromaticContact CZ-CE1 3.55Å; F689-F721 HydrophobicContact CZ-CE1 3.55Å; F689-F721 HydrophobicContact CZ-CZ 4.07Å; F689-M723 HydrophobicContact CB-CB 3.89Å; F689-M723 HydrophobicContact CB-CG 4.13Å; F689-M723 HydrophobicContact CB-SD 4.07Å; F689-M723 HydrophobicContact CD1-CB 4.34Å; F689-M723 HydrophobicContact CD1-CG 3.64Å; F689-M723 HydrophobicContact CD1-SD 3.31Å; F689-M723 WeakPolarHBondContact CD1-SD 3.32Å; F689-M723 HydrophobicContact CD2-CB 4.07Å; F689-M723 HydrophobicContact CD2-CG 3.99Å; F689-M723 HydrophobicContact CE1-CG 3.95Å; F689-M723 HydrophobicContact CE1-SD 3.85Å; F689-M723 HydrophobicContact CE2-CG 4.3Å; F689-M723 HydrophobicContact CG-CB 3.85Å; F689-M723 HydrophobicContact CG-CG 3.65Å; F689-M723 HydrophobicContact CG-SD 3.79Å; F689-M723 HydrophobicContact CZ-CG 4.27Å; F689-L737 HydrophobicContact CB-CD2 4.42Å; F689-F739 HydrophobicContact CE1-CD2 4.18Å; F689-F739 HydrophobicContact CE1-CE2 4.22Å; F689-F739 HydrophobicContact CZ-CE2 4.37Å
690A86.9Confident89.6Confident0 Ų044.7 Ų44.70%022%0.222CC..Hα-helixtrans-63.9-29.2173.800000113.3F642 M688 R694 D726 T730 I733F642-A690 HydrophobicContact CD1-CB 4.49Å; F642-A690 HydrophobicContact CE1-CB 4.2Å; F642-A690 HydrophobicContact CE2-CB 4.38Å; F642-A690 HydrophobicContact CZ-CB 4.16Å; M688-A690 VanDerWaalsContact C-N 3.34Å; M688-A690 PolarHBondContact O-N 3.42Å; A690-R694 WeakPolarHBondContact O-CG 3.38Å; A690-R694 PolarHBondContact O-N 2.84Å; A690-R694 VanDerWaalsContact O-N 3.13Å; A690-D726 HydrophobicContact CB-CB 4.2Å; A690-T730 HydrophobicContact CB-CG2 4.22Å; A690-I733 HydrophobicContact CB-CD1 3.68Å
691E88.2Confident89.5Confident88 Ų8845.2 Ų45.241%0.41123%0.226SC..Hα-helixtrans-71.6-44.4175.1-173.2171.7-154.700111C687 M688 F689 A693 R694 N695C687-E691 WeakPolarHBondContact CB-OE2 3.28Å; M688-E691 WeakPolarHBondContact O-CB 3.32Å; M688-E691 PolarHBondContact O-N 2.97Å; F689-E691 VanDerWaalsContact C-N 3.27Å; F689-E691 PolarHBondContact O-N 3.1Å; E691-A693 VanDerWaalsContact C-N 3.31Å; E691-A693 PolarHBondContact O-N 2.73Å; E691-R694 PolarHBondContact O-N 2.92Å; E691-N695 PolarHBondContact O-N 2.99Å; E691-N695 VanDerWaalsContact O-N 3.11Å; E691-N695 PolarHBondContact O-ND2 2.91Å
692K91.8Very high89.4Confident0 Ų048.4 Ų48.40%024%0.242CC..Hα-helixtrans-56.2-46.1171.9-58.6171.3-170.9-83.10111.3S664 L682 Q683 M688 F689 N695 I696 V706S664-K692 PolarHBondContact O-NZ 2.88Å; L682-K692 HydrophobicContact CD1-CB 4.1Å; Q683-K692 PolarHBondContact O-NZ 3.32Å; M688-K692 PolarHBondContact O-N 2.77Å; F689-K692 HydrophobicContact CD1-CD 4.32Å; F689-K692 WeakPolarHBondContact O-CB 3.49Å; F689-K692 PolarHBondContact O-N 2.94Å; K692-N695 PolarHBondContact O-N 2.83Å; K692-I696 PolarHBondContact O-N 2.79Å; K692-V706 HydrophobicContact CD-CG1 4.46Å
693A91.1Very high89.4Confident0 Ų048.4 Ų48.40%024%0.242CC..Hα-helixtrans-58.9-48.1179.100000112.1F642 F689 E691 N695 I696 Q697 I733 L735 L737F642-A693 HydrophobicContact CE2-CB 3.91Å; F689-A693 PolarHBondContact O-N 3.21Å; E691-A693 VanDerWaalsContact C-N 3.31Å; E691-A693 PolarHBondContact O-N 2.73Å; A693-N695 VanDerWaalsContact C-N 3.29Å; A693-N695 PolarHBondContact O-N 2.88Å; A693-I696 VanDerWaalsContact O-CG1 3.3Å; A693-I696 WeakPolarHBondContact O-CG1 3.37Å; A693-I696 PolarHBondContact O-N 3.23Å; A693-Q697 VanDerWaalsContact O-CB 3.31Å; A693-Q697 WeakPolarHBondContact O-CB 3.33Å; A693-Q697 PolarHBondContact O-N 3.4Å; A693-I733 HydrophobicContact CB-CD1 4.2Å; A693-I733 HydrophobicContact CB-CG2 3.81Å; A693-L735 HydrophobicContact CB-CD1 4.36Å; A693-L737 HydrophobicContact CB-CD2 4.33Å
694R91.9Very high89.5Confident51 Ų5145 Ų4519%0.19223%0.227CC..Hα-helixtrans-58.1-40.1175.3-71.8168.3177.1127.74.9112.5A690 E691 Q697 K698 D726 S729 D732 I733A690-R694 WeakPolarHBondContact O-CG 3.38Å; A690-R694 PolarHBondContact O-N 2.84Å; A690-R694 VanDerWaalsContact O-N 3.13Å; E691-R694 PolarHBondContact O-N 2.92Å; R694-Q697 PolarHBondContact O-N 2.84Å; R694-K698 WeakPolarHBondContact O-CB 3.39Å; R694-K698 PolarHBondContact O-N 2.85Å; R694-D726 IonicContact CZ-OD1 3.68Å; R694-D726 IonicContact NH1-OD1 2.6Å; R694-D726 PolarHBondContact NH1-OD1 3.11Å; R694-D726 IonicContact NH1-OD2 3.12Å; R694-D726 PolarHBondContact NH1-OD2 3.33Å; R694-D726 IonicContact NH2-OD1 3.04Å; R694-S729 PolarHBondContact NH2-O 3.04Å; R694-D732 IonicContact CZ-OD1 3.43Å; R694-D732 IonicContact CZ-OD2 2.71Å; R694-D732 IonicContact NE-OD1 3.26Å; R694-D732 PolarHBondContact NE-OD1 2.97Å; R694-D732 IonicContact NE-OD2 3.19Å; R694-D732 PolarHBondContact NE-OD2 3.31Å; R694-D732 IonicContact NH2-OD1 3.05Å; R694-D732 PolarHBondContact NH2-OD1 2.94Å; R694-D732 IonicContact NH2-OD2 3.37Å; R694-I733 HydrophobicContact CG-CD1 4.16Å; R694-I733 HydrophobicContact CG-CG1 3.9Å
695N91.8Very high89.8Confident27 Ų2741 Ų4114%0.14421%0.212CC..Hα-helixtrans-66.6-43.4179.5-69-26.9000112.4G665 S667 I669 E691 K692 A693 A699G665-N695 PolarHBondContact O-ND2 3.1Å; S667-N695 PolarHBondContact O-ND2 2.88Å; I669-N695 HydrophobicContact CD1-CB 4.28Å; I669-N695 HydrophobicContact CG1-CB 4.29Å; E691-N695 PolarHBondContact O-N 2.99Å; E691-N695 VanDerWaalsContact O-N 3.11Å; E691-N695 PolarHBondContact O-ND2 2.91Å; K692-N695 PolarHBondContact O-N 2.83Å; A693-N695 VanDerWaalsContact C-N 3.29Å; A693-N695 PolarHBondContact O-N 2.88Å; N695-A699 PolarHBondContact O-N 2.77Å
696I93.4Very high90.5Very high0 Ų039.7 Ų39.70%020%0.198CC..Hα-helixtrans-74.5-30.1175.963.5167.5000112.8I669 A680 L682 K692 A693 K698 A699 G700 A701 L735 L737I669-I696 HydrophobicContact CD1-CG2 4.16Å; I669-I696 HydrophobicContact CG1-CG2 4.15Å; A680-I696 HydrophobicContact CB-CB 3.95Å; A680-I696 HydrophobicContact CB-CD1 3.84Å; A680-I696 HydrophobicContact CB-CG1 4.5Å; A680-I696 HydrophobicContact CB-CG2 3.7Å; L682-I696 HydrophobicContact CD1-CD1 4.2Å; L682-I696 HydrophobicContact CD1-CG2 3.95Å; L682-I696 HydrophobicContact CD2-CG2 4.34Å; L682-I696 HydrophobicContact CG-CG2 4.45Å; K692-I696 PolarHBondContact O-N 2.79Å; A693-I696 VanDerWaalsContact O-CG1 3.3Å; A693-I696 WeakPolarHBondContact O-CG1 3.37Å; A693-I696 PolarHBondContact O-N 3.23Å; I696-K698 VanDerWaalsContact C-N 3.35Å; I696-A699 CarbonylContact O-C 3.28Å; I696-A699 WeakPolarHBondContact O-CA 3.32Å; I696-A699 WeakPolarHBondContact O-CB 3.38Å; I696-A699 PolarHBondContact O-N 3.17Å; I696-A699 VanDerWaalsContact O-N 3.13Å; I696-G700 PolarHBondContact O-N 2.85Å; I696-A701 HydrophobicContact CB-CB 3.95Å; I696-A701 HydrophobicContact CD1-CB 4.42Å; I696-A701 HydrophobicContact CG1-CB 4.38Å; I696-A701 WeakPolarHBondContact O-CB 3.48Å; I696-A701 PolarHBondContact O-N 3.43Å; I696-L735 HydrophobicContact CD1-CD1 4.01Å; I696-L735 HydrophobicContact CD1-CD2 4.04Å; I696-L735 HydrophobicContact CG1-CD1 4.48Å; I696-L735 HydrophobicContact CG1-CD2 3.78Å; I696-L737 HydrophobicContact CD1-CD1 3.85Å
697Q93.7Very high91.3Very high56 Ų5629.8 Ų29.826%0.26215%0.152SC..Hα-helixtrans-64-42172.6-162.3169.9-80.400111.1A693 R694 A699 G700 D732 T734 L735A693-Q697 VanDerWaalsContact O-CB 3.31Å; A693-Q697 WeakPolarHBondContact O-CB 3.33Å; A693-Q697 PolarHBondContact O-N 3.4Å; R694-Q697 PolarHBondContact O-N 2.84Å; Q697-A699 PolarHBondContact O-N 3.35Å; Q697-G700 PolarHBondContact O-N 3.05Å; Q697-D732 PolarHBondContact NE2-O 3.41Å; Q697-T734 PolarHBondContact OE1-OG1 3.4Å; Q697-L735 HydrophobicContact CB-CD2 3.53Å; Q697-L735 HydrophobicContact CG-CD2 3.97Å
698K91.8Very high91.6Very high152 Ų15229.2 Ų29.266%0.66115%0.148SC*.Hα-helixtrans-64.3-26.5173.4-171.9178179.3-178.90112.8E668 R694 I696 G700E668-K698 IonicContact OE1-NZ 3.79Å; E668-K698 PolarHBondContact OE1-NZ 3.38Å; R694-K698 WeakPolarHBondContact O-CB 3.39Å; R694-K698 PolarHBondContact O-N 2.85Å; I696-K698 VanDerWaalsContact C-N 3.35Å; K698-G700 VanDerWaalsContact C-N 3.32Å
699A91.1Very high91.7Very high10 Ų1028.6 Ų28.68%0.08315%0.146CC..THydrogen-bonded Turntrans-83.7-0.7172.600000114I669 A672 V675 N695 I696 Q697I669-A699 HydrophobicContact CB-CB 3.93Å; I669-A699 HydrophobicContact CG1-CB 4.13Å; I669-A699 HydrophobicContact CG2-CB 4.25Å; A672-A699 HydrophobicContact CB-CB 3.92Å; V675-A699 HydrophobicContact CB-CB 4.48Å; V675-A699 HydrophobicContact CG1-CB 4.04Å; N695-A699 PolarHBondContact O-N 2.77Å; I696-A699 CarbonylContact O-C 3.28Å; I696-A699 WeakPolarHBondContact O-CA 3.32Å; I696-A699 WeakPolarHBondContact O-CB 3.38Å; I696-A699 PolarHBondContact O-N 3.17Å; I696-A699 VanDerWaalsContact O-N 3.13Å; Q697-A699 PolarHBondContact O-N 3.35Å
700G91.3Very high91.5Very high33 Ų3332.2 Ų32.234%0.3417%0.167SC..THydrogen-bonded Turntrans78.920.9178.200000115.3Q676 G677 I696 Q697 K698Q676-G700 WeakPolarHBondContact CA-O 3.47Å; G677-G700 PolarHBondContact N-O 3.42Å; I696-G700 PolarHBondContact O-N 2.85Å; Q697-G700 PolarHBondContact O-N 3.05Å; K698-G700 VanDerWaalsContact C-N 3.32Å
701A94.2Very high91.2Very high10 Ų1040.2 Ų40.28%0.08320%0.204CC..  trans-65.4142.9173.100000111.7V675 H678 A680 I696V675-A701 HydrophobicContact CG1-CB 3.82Å; H678-A701 WeakPolarHBondContact O-CA 3.33Å; A680-A701 HydrophobicContact CB-CB 4.06Å; I696-A701 HydrophobicContact CB-CB 3.95Å; I696-A701 HydrophobicContact CD1-CB 4.42Å; I696-A701 HydrophobicContact CG1-CB 4.38Å; I696-A701 WeakPolarHBondContact O-CB 3.48Å; I696-A701 PolarHBondContact O-N 3.43Å
702I92.4Very high90.7Very high67 Ų6738.1 Ų38.134%0.34421%0.206SC..SBendtrans-87.2-12.5177.456.4166.1000113.4V653 G677 H678 I679 P736V653-I702 HydrophobicContact CG1-CD1 4.23Å; V653-I702 HydrophobicContact CG1-CG1 4.44Å; G677-I702 WeakPolarHBondContact O-CD1 3.32Å; H678-I702 WeakPolarHBondContact O-CG1 3.28Å; H678-I702 PolarHBondContact O-N 3Å; I679-I702 HydrophobicContact CG1-CD1 4.23Å; I679-I702 HydrophobicContact CG1-CG1 4.03Å; I702-P736 WeakPolarHBondContact O-CD 3.44Å
703G93.1Very high90.4Very high0 Ų038.7 Ų38.70%021%0.21CC..EExtended strand (participates in β ladder)trans-175.5176.5177.400000110.1I679 A680 P736I679-G703 WeakPolarHBondContact CA-O 3.32Å; A680-G703 PolarHBondContact N-O 2.98Å; G703-P736 WeakPolarHBondContact CA-O 3.4Å
704G94.2Very high90.1Very high0 Ų038.8 Ų38.80%021%0.21CC..EExtended strand (participates in β ladder)trans-151.5152.5175.300000114.9A680 P736 L737 L738A680-G704 CarbonylContact O-C 3.52Å; A680-G704 VanDerWaalsContact O-CA 3.24Å; A680-G704 WeakPolarHBondContact O-CA 3.44Å; G704-P736 PolarHBondContact N-O 2.91Å; G704-L737 WeakPolarHBondContact O-CA 3.29Å; G704-L738 PolarHBondContact O-N 2.7Å
705I95.6Very high89.6Confident0 Ų037.6 Ų37.60%021%0.21CC..EExtended strand (participates in β ladder)trans-123.6128.4179.6-58.4168.8000107.7I622 I679 A680 L681 L682 L738 L740 L748 V760 L762I622-I705 HydrophobicContact CD1-CD1 3.99Å; I622-I705 HydrophobicContact CD1-CG1 3.93Å; I622-I705 HydrophobicContact CD1-CG2 4.09Å; I622-I705 HydrophobicContact CG2-CD1 4.3Å; I679-I705 HydrophobicContact CG2-CD1 3.87Å; I679-I705 HydrophobicContact CG2-CG1 3.9Å; A680-I705 PolarHBondContact O-N 3.3Å; L681-I705 HydrophobicContact CD1-CB 3.65Å; L681-I705 HydrophobicContact CD1-CG2 3.63Å; L682-I705 PolarHBondContact N-O 3.47Å; I705-L738 CarbonylContact C-O 3.16Å; I705-L738 WeakPolarHBondContact CA-O 3.49Å; I705-L740 HydrophobicContact CG2-CD1 3.79Å; I705-L740 HydrophobicContact CG2-CG 4.03Å; I705-L748 HydrophobicContact CD1-CD2 3.78Å; I705-L748 HydrophobicContact CG2-CD2 4.45Å; I705-V760 HydrophobicContact CD1-CG2 4.2Å; I705-L762 HydrophobicContact CD1-CD2 4Å; I705-L762 HydrophobicContact CG1-CD2 4.06Å
706V94.1Very high88.9Confident0 Ų043 Ų430%024%0.239CC..EExtended strand (participates in β ladder)trans-113.6116178.1-169.50000109.8L682 R684 F689 K692 M723 L737 L738 F739 L740L682-V706 HydrophobicContact CB-CG2 4.24Å; L682-V706 HydrophobicContact CD1-CG2 4.29Å; L682-V706 CarbonylContact O-C 3.53Å; L682-V706 WeakPolarHBondContact O-CA 3.26Å; R684-V706 HydrophobicContact CB-CG1 4.49Å; F689-V706 HydrophobicContact CD1-CG1 4.14Å; F689-V706 HydrophobicContact CD1-CG2 4.44Å; F689-V706 HydrophobicContact CE1-CG1 3.93Å; K692-V706 HydrophobicContact CD-CG1 4.46Å; V706-M723 HydrophobicContact CB-SD 4.08Å; V706-M723 HydrophobicContact CG2-SD 3.94Å; V706-L737 HydrophobicContact CG2-CD1 4.37Å; V706-L737 HydrophobicContact CG2-CD2 3.99Å; V706-L737 HydrophobicContact CG2-CG 4.2Å; V706-L738 PolarHBondContact N-O 2.58Å; V706-F739 HydrophobicContact CB-CD2 4.36Å; V706-F739 WeakPolarHBondContact O-CA 3.41Å; V706-F739 WeakPolarHBondContact O-CD2 3.17Å; V706-L740 PolarHBondContact O-N 3.15Å
707I92.9Very high87.9Confident3 Ų347.7 Ų47.72%0.01527%0.267CS..EExtended strand (participates in β ladder)trans-88.4135.3177.2-62.6175.1000110.3L681 L682 Q683 R684 L740 L749L681-I707 HydrophobicContact CD1-CD1 3.77Å; L681-I707 HydrophobicContact CD1-CG1 4.01Å; L681-I707 HydrophobicContact CD2-CD1 4.15Å; L681-I707 HydrophobicContact CG-CD1 4.2Å; L682-I707 PolarHBondContact O-N 3.4Å; Q683-I707 CarbonylContact C-O 3.36Å; Q683-I707 WeakPolarHBondContact CA-O 3.46Å; R684-I707 WeakPolarHBondContact CB-O 3.16Å; R684-I707 PolarHBondContact N-O 2.98Å; I707-L740 CarbonylContact C-O 3.03Å; I707-L740 WeakPolarHBondContact CA-O 3.32Å; I707-L740 HydrophobicContact CG1-CB 4.38Å; I707-L749 HydrophobicContact CD1-CD1 3.65Å; I707-L749 HydrophobicContact CD1-CD2 4.28Å; I707-L749 HydrophobicContact CD1-CG 3.71Å
708D90.4Very high86.9Confident3 Ų346.7 Ų46.72%0.01627%0.269CS..  trans-60.3141.6175.8-162.728000113.3R684 S713 F739 L740 F741R684-D708 WeakPolarHBondContact CD-OD1 3.46Å; R684-D708 IonicContact CZ-OD1 2.67Å; R684-D708 IonicContact NE-OD1 3.6Å; R684-D708 IonicContact NH1-OD1 3.78Å; R684-D708 PolarHBondContact NH1-OD1 2.92Å; D708-S713 WeakPolarHBondContact OD2-CB 3.28Å; D708-S713 PolarHBondContact OD2-OG 3.43Å; D708-F739 HydrophobicContact CB-CE1 4.26Å; D708-F739 HydrophobicContact CB-CE2 4.31Å; D708-F739 HydrophobicContact CB-CZ 3.62Å; D708-L740 PolarHBondContact N-O 3Å; D708-F741 HydrophobicContact CB-CD1 4.47Å
709D86.1Confident86Confident79 Ų7944.1 Ų44.142%0.42227%0.268SS..SBendtrans-92-2.1-179.661.6-17.7000113.7Q683 R684Q683-D709 HydrophobicContact CG-CB 4.3Å; R684-D709 HydrophobicContact CB-CB 4.17Å; R684-D709 VanDerWaalsContact CD-OD1 3.23Å; R684-D709 WeakPolarHBondContact CD-OD1 3.27Å; R684-D709 WeakPolarHBondContact CG-OD1 3.34Å; R684-D709 IonicContact NE-OD1 3.89Å
710N84.8Confident85Confident98 Ų9845.5 Ų45.552%0.52427%0.274SS..SBendtrans-91.9104178.6179.253.5000111.7G712 S713 H742N710-G712 PolarHBondContact O-N 3.26Å; N710-S713 PolarHBondContact O-N 2.97Å; N710-S713 PolarHBondContact O-OG 2.87Å; N710-H742 WeakPolarHBondContact O-CB 3.17Å
711E81.6Confident83.8Confident168 Ų16847.2 Ų47.279%0.78527%0.272SS*.THydrogen-bonded Turntrans-52.1124.1-177.5-67.3-173.3173.900112.9
712G77.5Confident83Confident44 Ų4448.3 Ų48.345%0.45428%0.275SS..THydrogen-bonded Turntrans89.2-0.3175.100000116.1N710 H742 K743N710-G712 PolarHBondContact O-N 3.26Å; G712-H742 PolarHBondContact N-ND1 3.16Å; G712-K743 WeakPolarHBondContact O-CE 3.5Å
713S84.6Confident82.5Confident12 Ų1245.1 Ų45.18%0.08426%0.259CS..  trans-60.5149.5169.568.80000112D708 N710 H742 K743D708-S713 WeakPolarHBondContact OD2-CB 3.28Å; D708-S713 PolarHBondContact OD2-OG 3.43Å; N710-S713 PolarHBondContact O-N 2.97Å; N710-S713 PolarHBondContact O-OG 2.87Å; S713-H742 PolarHBondContact O-N 3.3Å; S713-H742 WeakPolarHBondContact OG-CB 3.17Å; S713-H742 PolarHBondContact OG-N 2.77Å; S713-K743 PolarHBondContact O-N 3.35Å
714S85.4Confident81.8Confident1 Ų147 Ų471%0.00728%0.275CS..  trans-167.8147.1-173.9170.20000112.3D716 T717 A718 K743 E744S714-D716 PolarHBondContact O-N 3.48Å; S714-T717 PolarHBondContact O-N 3.18Å; S714-T717 PolarHBondContact O-OG1 2.92Å; S714-A718 PolarHBondContact O-N 3.08Å; S714-A718 VanDerWaalsContact O-N 3.15Å; S714-K743 PolarHBondContact OG-NZ 3.38Å; S714-K743 VanDerWaalsContact OG-NZ 3.09Å; S714-E744 WeakPolarHBondContact CA-OE1 3.45Å; S714-E744 WeakPolarHBondContact CA-OE2 3.36Å; S714-E744 WeakPolarHBondContact CB-OE1 3.09Å; S714-E744 PolarHBondContact OG-OE1 3.19Å
715S82Confident80.9Confident26 Ų2648.1 Ų48.118%0.18229%0.286CS..THydrogen-bonded Turntrans-61-27.1-176.650.80000113.6T717 E744S715-T717 PolarHBondContact O-N 2.8Å; S715-E744 PolarHBondContact N-OE1 2.99Å; S715-E744 PolarHBondContact OG-OE1 2.68Å
716D76.9Confident79.9Confident140 Ų14049.8 Ų49.875%0.74930%0.295SS*.THydrogen-bonded Turntrans-73.6-13.1179-53.4-12.2000112.6S714S714-D716 PolarHBondContact O-N 3.48Å
717T73.3Confident78.5Confident99 Ų9953.7 Ų53.761%0.60734%0.335SS*.THydrogen-bonded Turntrans-125.7-13.3-167.2590000114.4S714 S715S714-T717 PolarHBondContact O-N 3.18Å; S714-T717 PolarHBondContact O-OG1 2.92Å; S715-T717 PolarHBondContact O-N 2.8Å
718A72.4Confident77.5Confident36 Ų3662.7 Ų62.730%0.29837%0.368SS..SBendtrans-142.6141.8177.400000109.9S714 F741S714-A718 PolarHBondContact O-N 3.08Å; S714-A718 VanDerWaalsContact O-N 3.15Å; A718-F741 HydrophobicContact CB-CE1 4.4Å; A718-F741 HydrophobicContact CB-CZ 4.04Å
719P71.9Confident76.7Confident98 Ų9866 Ų6664%0.63639%0.392SS*.PPolyproline II helixtrans-60.4143.1175.127.8-35000110.2F721P719-F721 PolarHBondContact O-N 2.61Å
720L70.4Confident76.4Confident39 Ų3963.8 Ų63.820%0.20438%0.381CS..PPolyproline II helixtrans-57.8134.8-173.6-76.5158.3000111.9Q616 P619 T636 F741Q616-L720 PolarHBondContact NE2-O 3.26Å; P619-L720 HydrophobicContact CB-CD1 3.68Å; P619-L720 HydrophobicContact CG-CD1 4.21Å; T636-L720 HydrophobicContact CG2-CD1 4.18Å; T636-L720 HydrophobicContact CG2-CD2 4.07Å; L720-F741 HydrophobicContact CD2-CE2 4.21Å
721F66.3Low76.2Confident68 Ų6865.8 Ų65.830%0.29839%0.392SS..PPolyproline II helixtrans-90.4126.8-177.3179-96.3000110.8G638 F689 P719 M723 F739 F741G638-F721 WeakPolarHBondContact CA-O 3.09Å; F689-F721 HydrophobicContact CD2-CE1 4.41Å; F689-F721 HydrophobicContact CE1-CE1 4.47Å; F689-F721 AromaticContact CE2-CE1 3.53Å; F689-F721 HydrophobicContact CE2-CE1 3.53Å; F689-F721 AromaticContact CE2-CZ 3.73Å; F689-F721 HydrophobicContact CE2-CZ 3.73Å; F689-F721 AromaticContact CZ-CE1 3.55Å; F689-F721 HydrophobicContact CZ-CE1 3.55Å; F689-F721 HydrophobicContact CZ-CZ 4.07Å; P719-F721 PolarHBondContact O-N 2.61Å; F721-M723 HydrophobicContact CD1-CG 4.38Å; F721-M723 HydrophobicContact CE1-CG 4.06Å; F721-F739 HydrophobicContact CB-CD1 3.93Å; F721-F739 HydrophobicContact CB-CE1 3.8Å; F721-F739 HydrophobicContact CB-CZ 4.5Å; F721-F739 AromaticContact CD1-CD1 3.97Å; F721-F739 HydrophobicContact CD1-CD1 3.97Å; F721-F739 HydrophobicContact CD1-CD2 4.05Å; F721-F739 AromaticContact CD1-CE1 3.97Å; F721-F739 HydrophobicContact CD1-CE1 3.97Å; F721-F739 HydrophobicContact CD1-CE2 4.05Å; F721-F739 AromaticContact CD1-CG 3.99Å; F721-F739 HydrophobicContact CD1-CG 3.99Å; F721-F739 HydrophobicContact CD1-CZ 4Å; F721-F739 HydrophobicContact CE1-CE2 4.48Å; F721-F739 HydrophobicContact CG-CD1 4.41Å; F721-F739 HydrophobicContact CG-CE1 4.19Å; F721-F739 HydrophobicContact CG-CZ 4.44Å; F721-F741 HydrophobicContact CB-CE1 4.46Å; F721-F741 HydrophobicContact CB-CZ 4.25Å
722Q77.4Confident76.3Confident33 Ų3361.4 Ų61.415%0.15437%0.374CS..PPolyproline II helixtrans-90.2135.8171.2-72.4-175.8-4.400111.2E615 P639 A724E615-Q722 PolarHBondContact O-NE2 3.38Å; E615-Q722 VanDerWaalsContact O-NE2 3.15Å; P639-Q722 HydrophobicContact CG-CG 4.34Å; P639-Q722 WeakPolarHBondContact O-CA 3.45Å; Q722-A724 PolarHBondContact O-N 3.02Å
723M82.2Confident76.8Confident0 Ų059.7 Ų59.70%035%0.354CS..BIsolated β-bridgetrans-82.3103.6171.9-67.6-176.7-67.600110.4P639 A640 Q641 F642 F689 V706 F721 L737 F739P639-M723 PolarHBondContact O-N 3.21Å; A640-M723 HydrophobicContact CB-CB 4.21Å; A640-M723 HydrophobicContact CB-CE 4.18Å; Q641-M723 PolarHBondContact N-O 3.29Å; F642-M723 HydrophobicContact CE1-CB 4.27Å; F642-M723 VanDerWaalsContact CE1-O 3.22Å; F642-M723 WeakPolarHBondContact CE1-O 3.43Å; F642-M723 HydrophobicContact CZ-CB 4.34Å; F689-M723 HydrophobicContact CB-CB 3.89Å; F689-M723 HydrophobicContact CB-CG 4.13Å; F689-M723 HydrophobicContact CB-SD 4.07Å; F689-M723 HydrophobicContact CD1-CB 4.34Å; F689-M723 HydrophobicContact CD1-CG 3.64Å; F689-M723 HydrophobicContact CD1-SD 3.31Å; F689-M723 WeakPolarHBondContact CD1-SD 3.32Å; F689-M723 HydrophobicContact CD2-CB 4.07Å; F689-M723 HydrophobicContact CD2-CG 3.99Å; F689-M723 HydrophobicContact CE1-CG 3.95Å; F689-M723 HydrophobicContact CE1-SD 3.85Å; F689-M723 HydrophobicContact CE2-CG 4.3Å; F689-M723 HydrophobicContact CG-CB 3.85Å; F689-M723 HydrophobicContact CG-CG 3.65Å; F689-M723 HydrophobicContact CG-SD 3.79Å; F689-M723 HydrophobicContact CZ-CG 4.27Å; V706-M723 HydrophobicContact CB-SD 4.08Å; V706-M723 HydrophobicContact CG2-SD 3.94Å; F721-M723 HydrophobicContact CD1-CG 4.38Å; F721-M723 HydrophobicContact CE1-CG 4.06Å; M723-L737 HydrophobicContact CE-CB 4.03Å; M723-L737 HydrophobicContact CE-CD2 3.69Å; M723-L737 HydrophobicContact CE-CG 3.74Å; M723-L737 WeakPolarHBondContact CE-O 3.32Å; M723-L737 HydrophobicContact SD-CD2 3.79Å; M723-L737 HydrophobicContact SD-CG 4.4Å; M723-F739 HydrophobicContact CE-CB 3.88Å; M723-F739 HydrophobicContact CG-CB 4.06Å; M723-F739 HydrophobicContact CG-CD2 4.26Å; M723-F739 HydrophobicContact CG-CG 4.47Å; M723-F739 HydrophobicContact SD-CB 3.93Å; M723-F739 HydrophobicContact SD-CD2 4.11Å; M723-F739 HydrophobicContact SD-CG 4.5Å
724A78.4Confident77Confident41 Ų4163.5 Ų63.534%0.33938%0.377SS..  trans-79.8155.8174.400000112.8Q722Q722-A724 PolarHBondContact O-N 3.02Å
725G73.9Confident77.1Confident22 Ų2263.9 Ų63.923%0.22738%0.379CS..  trans-70.4174.5179.800000114.9M688 G727M688-G725 VanDerWaalsContact CE-O 3.32Å; M688-G725 WeakPolarHBondContact CE-O 3.21Å; G725-G727 VanDerWaalsContact C-N 3.27Å; G725-G727 PolarHBondContact O-N 2.75Å
726D75.1Confident77.6Confident36 Ų3662.9 Ų62.919%0.19337%0.372CS..  trans-86.315.1-17970.5-41.8000114.5M688 A690 R694 R728M688-D726 HydrophobicContact CB-CB 3.86Å; M688-D726 HydrophobicContact CG-CB 4.05Å; A690-D726 HydrophobicContact CB-CB 4.2Å; R694-D726 IonicContact CZ-OD1 3.68Å; R694-D726 IonicContact NH1-OD1 2.6Å; R694-D726 PolarHBondContact NH1-OD1 3.11Å; R694-D726 IonicContact NH1-OD2 3.12Å; R694-D726 PolarHBondContact NH1-OD2 3.33Å; R694-D726 IonicContact NH2-OD1 3.04Å; D726-R728 PolarHBondContact O-N 3.01Å; D726-R728 VanDerWaalsContact OD2-CD 3.29Å; D726-R728 WeakPolarHBondContact OD2-CD 3.42Å; D726-R728 IonicContact OD2-NE 3.74Å
727G65.8Low78.4Confident81 Ų8156.4 Ų56.484%0.83534%0.337SS*.SBendtrans74.38.9-176.300000114.5G725G725-G727 VanDerWaalsContact C-N 3.27Å; G725-G727 PolarHBondContact O-N 2.75Å
728R71.1Confident79.3Confident192 Ų19251.9 Ų51.973%0.72531%0.309SS*.SBendtrans-102173.1167.8-57.1-176.8-178.5160.92.5109.2D726 T730D726-R728 PolarHBondContact O-N 3.01Å; D726-R728 VanDerWaalsContact OD2-CD 3.29Å; D726-R728 WeakPolarHBondContact OD2-CD 3.42Å; D726-R728 IonicContact OD2-NE 3.74Å; R728-T730 PolarHBondContact O-N 3.24Å
729S72.8Confident80.3Confident72 Ų7250.3 Ų50.350%0.50330%0.296SS..  trans-56.3138.5160.3150.30000108.4R694 D731R694-S729 PolarHBondContact NH2-O 3.04Å; S729-D731 WeakPolarHBondContact CB-OD2 3.49Å; S729-D731 PolarHBondContact OG-N 3.39Å; S729-D731 PolarHBondContact OG-OD2 2.88Å
730T81.1Confident81.3Confident33 Ų3345.6 Ų45.620%0.20227%0.266CS..  trans-113.813.5176.451.90000111.8F642 A690 R728 D732 I733F642-T730 HydrophobicContact CB-CG2 4.13Å; F642-T730 HydrophobicContact CG-CG2 4.43Å; A690-T730 HydrophobicContact CB-CG2 4.22Å; R728-T730 PolarHBondContact O-N 3.24Å; T730-D732 PolarHBondContact O-N 2.6Å; T730-D732 VanDerWaalsContact O-N 3.14Å; T730-I733 HydrophobicContact CG2-CD1 4.28Å; T730-I733 PolarHBondContact O-N 3.14Å
731D80.4Confident82.4Confident141 Ų14144.4 Ų44.475%0.75426%0.259SS*.THydrogen-bonded Turntrans-66.8-11-179.9-49.2-63.7000112.3S729S729-D731 WeakPolarHBondContact CB-OD2 3.49Å; S729-D731 PolarHBondContact OG-N 3.39Å; S729-D731 PolarHBondContact OG-OD2 2.88Å
732D83.8Confident83.6Confident76 Ų7643 Ų4341%0.40625%0.253SS..THydrogen-bonded Turntrans-84.6-7.5173.970-49.9000113.8R694 Q697 T730R694-D732 IonicContact CZ-OD1 3.43Å; R694-D732 IonicContact CZ-OD2 2.71Å; R694-D732 IonicContact NE-OD1 3.26Å; R694-D732 PolarHBondContact NE-OD1 2.97Å; R694-D732 IonicContact NE-OD2 3.19Å; R694-D732 PolarHBondContact NE-OD2 3.31Å; R694-D732 IonicContact NH2-OD1 3.05Å; R694-D732 PolarHBondContact NH2-OD1 2.94Å; R694-D732 IonicContact NH2-OD2 3.37Å; Q697-D732 PolarHBondContact NE2-O 3.41Å; T730-D732 PolarHBondContact O-N 2.6Å; T730-D732 VanDerWaalsContact O-N 3.14Å
733I88.3Confident84.2Confident8 Ų845.8 Ų45.84%0.04126%0.264CS..  trans-101.5116.2-179.9-55.1168.4000109.3F642 G643 A690 A693 R694 T730 L735F642-I733 HydrophobicContact CD2-CB 4.41Å; F642-I733 HydrophobicContact CD2-CD1 3.82Å; F642-I733 HydrophobicContact CD2-CG2 3.98Å; F642-I733 HydrophobicContact CE2-CD1 4.27Å; F642-I733 HydrophobicContact CG-CD1 4.39Å; G643-I733 WeakPolarHBondContact CA-O 3.45Å; A690-I733 HydrophobicContact CB-CD1 3.68Å; A693-I733 HydrophobicContact CB-CD1 4.2Å; A693-I733 HydrophobicContact CB-CG2 3.81Å; R694-I733 HydrophobicContact CG-CD1 4.16Å; R694-I733 HydrophobicContact CG-CG1 3.9Å; T730-I733 HydrophobicContact CG2-CD1 4.28Å; T730-I733 PolarHBondContact O-N 3.14Å; I733-L735 HydrophobicContact CG2-CG 4.46Å
734T87.6Confident84.6Confident92 Ų9246.5 Ų46.556%0.56427%0.268SS*.  trans-114.6-14.5-175.260.30000113.7T644 Q697T644-T734 VanDerWaalsContact CB-O 3.27Å; T644-T734 WeakPolarHBondContact CB-O 3.46Å; T644-T734 PolarHBondContact N-O 2.83Å; T644-T734 PolarHBondContact OG1-O 3.01Å; Q697-T734 PolarHBondContact OE1-OG1 3.4Å
735L89.1Confident85.2Confident8 Ų844.6 Ų44.64%0.04225%0.252CS..SBendtrans-78.3148.41756486.2000111.9G643 T644 A693 I696 Q697 I733 L737G643-L735 WeakPolarHBondContact CA-O 3.02Å; T644-L735 PolarHBondContact N-O 3.26Å; A693-L735 HydrophobicContact CB-CD1 4.36Å; I696-L735 HydrophobicContact CD1-CD1 4.01Å; I696-L735 HydrophobicContact CD1-CD2 4.04Å; I696-L735 HydrophobicContact CG1-CD1 4.48Å; I696-L735 HydrophobicContact CG1-CD2 3.78Å; Q697-L735 HydrophobicContact CB-CD2 3.53Å; Q697-L735 HydrophobicContact CG-CD2 3.97Å; I733-L735 HydrophobicContact CG2-CG 4.46Å; L735-L737 HydrophobicContact CD1-CB 4.28Å; L735-L737 HydrophobicContact CD1-CD1 3.88Å
736P91.9Very high86Confident5 Ų545.9 Ų45.93%0.03225%0.253CS..  trans-74.9139.4169.331.7-34000110.7L646 V653 I702 G703 G704 L762L646-P736 HydrophobicContact CD1-CB 4.28Å; L646-P736 HydrophobicContact CD2-CB 3.79Å; L646-P736 HydrophobicContact CD2-CG 4.15Å; L646-P736 HydrophobicContact CG-CB 3.97Å; V653-P736 HydrophobicContact CB-CG 4.28Å; V653-P736 HydrophobicContact CG2-CG 3.88Å; I702-P736 WeakPolarHBondContact O-CD 3.44Å; G703-P736 WeakPolarHBondContact CA-O 3.4Å; G704-P736 PolarHBondContact N-O 2.91Å; P736-L762 HydrophobicContact CG-CD1 4.41Å
737L92.4Very high86.8Confident4 Ų447.7 Ų47.72%0.02126%0.263CS..EExtended strand (participates in β ladder)trans-128.7127.9177.5-157.682.4000110.3A640 F642 F689 A693 I696 G704 V706 M723 L735A640-L737 HydrophobicContact CB-CB 4.17Å; A640-L737 WeakPolarHBondContact CB-O 3.32Å; A640-L737 PolarHBondContact N-O 2.88Å; F642-L737 HydrophobicContact CE2-CB 4.44Å; F642-L737 HydrophobicContact CE2-CD2 4.02Å; F642-L737 HydrophobicContact CZ-CD2 4.05Å; F689-L737 HydrophobicContact CB-CD2 4.42Å; A693-L737 HydrophobicContact CB-CD2 4.33Å; I696-L737 HydrophobicContact CD1-CD1 3.85Å; G704-L737 WeakPolarHBondContact O-CA 3.29Å; V706-L737 HydrophobicContact CG2-CD1 4.37Å; V706-L737 HydrophobicContact CG2-CD2 3.99Å; V706-L737 HydrophobicContact CG2-CG 4.2Å; M723-L737 HydrophobicContact CE-CB 4.03Å; M723-L737 HydrophobicContact CE-CD2 3.69Å; M723-L737 HydrophobicContact CE-CG 3.74Å; M723-L737 WeakPolarHBondContact CE-O 3.32Å; M723-L737 HydrophobicContact SD-CD2 3.79Å; M723-L737 HydrophobicContact SD-CG 4.4Å; L735-L737 HydrophobicContact CD1-CB 4.28Å; L735-L737 HydrophobicContact CD1-CD1 3.88Å
738L93.6Very high88Confident4 Ų443.9 Ų43.92%0.02122%0.223CC..EExtended strand (participates in β ladder)trans-121.9148.1-179.1-67-173.8000112.4R620 I622 A637 L646 G704 I705 V706 L762R620-L738 HydrophobicContact CB-CD1 4.07Å; R620-L738 HydrophobicContact CB-CD2 3.57Å; R620-L738 HydrophobicContact CG-CD2 3.73Å; I622-L738 HydrophobicContact CD1-CB 4Å; I622-L738 HydrophobicContact CD1-CD1 3.99Å; I622-L738 HydrophobicContact CG1-CD1 3.64Å; A637-L738 HydrophobicContact CB-CB 4.1Å; A637-L738 HydrophobicContact CB-CD1 4.23Å; L646-L738 HydrophobicContact CD1-CD1 3.95Å; L646-L738 HydrophobicContact CD1-CD2 4.15Å; L646-L738 HydrophobicContact CD1-CG 4.23Å; G704-L738 PolarHBondContact O-N 2.7Å; I705-L738 CarbonylContact C-O 3.16Å; I705-L738 WeakPolarHBondContact CA-O 3.49Å; V706-L738 PolarHBondContact N-O 2.58Å; L738-L762 HydrophobicContact CD1-CB 4.04Å; L738-L762 HydrophobicContact CD1-CD2 4.23Å
739F93.3Very high89Confident3 Ų336.2 Ų36.21%0.01320%0.196CC..EExtended strand (participates in β ladder)trans-108.9129.3-178.5-176.2-97.7000111.2A637 G638 F689 V706 D708 F721 M723 F741A637-F739 CarbonylContact C-O 3.45Å; A637-F739 WeakPolarHBondContact CA-O 3.37Å; A637-F739 WeakPolarHBondContact CB-O 3.2Å; G638-F739 PolarHBondContact N-O 2.83Å; G638-F739 PolarHBondContact O-N 3.23Å; F689-F739 HydrophobicContact CE1-CD2 4.18Å; F689-F739 HydrophobicContact CE1-CE2 4.22Å; F689-F739 HydrophobicContact CZ-CE2 4.37Å; V706-F739 HydrophobicContact CB-CD2 4.36Å; V706-F739 WeakPolarHBondContact O-CA 3.41Å; V706-F739 WeakPolarHBondContact O-CD2 3.17Å; D708-F739 HydrophobicContact CB-CE1 4.26Å; D708-F739 HydrophobicContact CB-CE2 4.31Å; D708-F739 HydrophobicContact CB-CZ 3.62Å; F721-F739 HydrophobicContact CB-CD1 3.93Å; F721-F739 HydrophobicContact CB-CE1 3.8Å; F721-F739 HydrophobicContact CB-CZ 4.5Å; F721-F739 AromaticContact CD1-CD1 3.97Å; F721-F739 HydrophobicContact CD1-CD1 3.97Å; F721-F739 HydrophobicContact CD1-CD2 4.05Å; F721-F739 AromaticContact CD1-CE1 3.97Å; F721-F739 HydrophobicContact CD1-CE1 3.97Å; F721-F739 HydrophobicContact CD1-CE2 4.05Å; F721-F739 AromaticContact CD1-CG 3.99Å; F721-F739 HydrophobicContact CD1-CG 3.99Å; F721-F739 HydrophobicContact CD1-CZ 4Å; F721-F739 HydrophobicContact CE1-CE2 4.48Å; F721-F739 HydrophobicContact CG-CD1 4.41Å; F721-F739 HydrophobicContact CG-CE1 4.19Å; F721-F739 HydrophobicContact CG-CZ 4.44Å; M723-F739 HydrophobicContact CE-CB 3.88Å; M723-F739 HydrophobicContact CG-CB 4.06Å; M723-F739 HydrophobicContact CG-CD2 4.26Å; M723-F739 HydrophobicContact CG-CG 4.47Å; M723-F739 HydrophobicContact SD-CB 3.93Å; M723-F739 HydrophobicContact SD-CD2 4.11Å; M723-F739 HydrophobicContact SD-CG 4.5Å; F739-F741 AromaticContact CE1-CD1 3.8Å; F739-F741 HydrophobicContact CE1-CD1 3.8Å; F739-F741 AromaticContact CE1-CE1 3.92Å; F739-F741 HydrophobicContact CE1-CE1 3.92Å; F739-F741 HydrophobicContact CE1-CG 4.3Å
740L93.3Very high89.8Confident0 Ų038.4 Ų38.40%020%0.199CC..EExtended strand (participates in β ladder)trans-111.9136.9170.6-72.1179.2000110.3I622 L635 T636 A637 I705 V706 I707 D708 E744 L748I622-L740 HydrophobicContact CD1-CD1 4.07Å; I622-L740 HydrophobicContact CD1-CD2 4.07Å; I622-L740 HydrophobicContact CD1-CG 3.97Å; L635-L740 HydrophobicContact CB-CD2 3.92Å; L635-L740 HydrophobicContact CD1-CD1 4.07Å; T636-L740 WeakPolarHBondContact O-CD2 3.4Å; A637-L740 HydrophobicContact CB-CD2 3.94Å; I705-L740 HydrophobicContact CG2-CD1 3.79Å; I705-L740 HydrophobicContact CG2-CG 4.03Å; V706-L740 PolarHBondContact O-N 3.15Å; I707-L740 CarbonylContact C-O 3.03Å; I707-L740 WeakPolarHBondContact CA-O 3.32Å; I707-L740 HydrophobicContact CG1-CB 4.38Å; D708-L740 PolarHBondContact N-O 3Å; L740-E744 HydrophobicContact CD2-CB 4.18Å; L740-L748 HydrophobicContact CD1-CD2 4.33Å
741F92.5Very high90.2Very high14 Ų1437 Ų376%0.06119%0.19CC..  trans-69.2166.2165-74.6-62.7000111D708 A718 L720 F721 F739 K743 E744 G745D708-F741 HydrophobicContact CB-CD1 4.47Å; A718-F741 HydrophobicContact CB-CE1 4.4Å; A718-F741 HydrophobicContact CB-CZ 4.04Å; L720-F741 HydrophobicContact CD2-CE2 4.21Å; F721-F741 HydrophobicContact CB-CE1 4.46Å; F721-F741 HydrophobicContact CB-CZ 4.25Å; F739-F741 AromaticContact CE1-CD1 3.8Å; F739-F741 HydrophobicContact CE1-CD1 3.8Å; F739-F741 AromaticContact CE1-CE1 3.92Å; F739-F741 HydrophobicContact CE1-CE1 3.92Å; F739-F741 HydrophobicContact CE1-CG 4.3Å; F741-K743 PolarHBondContact O-N 3.19Å; F741-E744 WeakPolarHBondContact CB-OE2 3.21Å; F741-E744 PolarHBondContact O-N 2.96Å; F741-G745 PolarHBondContact O-N 2.73Å
742H91Very high90.6Very high38 Ų3832.3 Ų32.318%0.17617%0.165CC..Hα-helixtrans-64.5-37.6-166.1178.2-85.8000113.9N710 G712 S713 N746N710-H742 WeakPolarHBondContact O-CB 3.17Å; G712-H742 PolarHBondContact N-ND1 3.16Å; S713-H742 PolarHBondContact O-N 3.3Å; S713-H742 WeakPolarHBondContact OG-CB 3.17Å; S713-H742 PolarHBondContact OG-N 2.77Å; H742-N746 PolarHBondContact CE1-ND2 3.41Å; H742-N746 WeakPolarHBondContact O-CB 3.23Å; H742-N746 VanDerWaalsContact O-CG 3.32Å; H742-N746 PolarHBondContact O-N 2.94Å
743K89.8Confident90.8Very high91 Ų9136.1 Ų36.140%0.39618%0.178SC..Hα-helixtrans-67.2-45.5178.1-67.2-172.1-145.9148.70111.8G712 S713 S714 F741 N746 I747G712-K743 WeakPolarHBondContact O-CE 3.5Å; S713-K743 PolarHBondContact O-N 3.35Å; S714-K743 PolarHBondContact OG-NZ 3.38Å; S714-K743 VanDerWaalsContact OG-NZ 3.09Å; F741-K743 PolarHBondContact O-N 3.19Å; K743-N746 WeakPolarHBondContact O-CB 3.3Å; K743-N746 PolarHBondContact O-N 2.78Å; K743-I747 PolarHBondContact O-N 3.49Å
744E91.9Very high90.7Very high16 Ų1642.3 Ų42.38%0.07521%0.207CC..Hα-helixtrans-71-39.8-175.9-59.476.3-173.800110L635 S714 S715 L740 F741 N746 I747L635-E744 HydrophobicContact CD2-CB 4.39Å; S714-E744 WeakPolarHBondContact CA-OE1 3.45Å; S714-E744 WeakPolarHBondContact CA-OE2 3.36Å; S714-E744 WeakPolarHBondContact CB-OE1 3.09Å; S714-E744 PolarHBondContact OG-OE1 3.19Å; S715-E744 PolarHBondContact N-OE1 2.99Å; S715-E744 PolarHBondContact OG-OE1 2.68Å; L740-E744 HydrophobicContact CD2-CB 4.18Å; F741-E744 WeakPolarHBondContact CB-OE2 3.21Å; F741-E744 PolarHBondContact O-N 2.96Å; E744-N746 VanDerWaalsContact C-N 3.33Å; E744-N746 PolarHBondContact O-N 3.07Å; E744-I747 PolarHBondContact O-N 3.38Å
745G90.8Very high90.6Very high0 Ų041 Ų410%019%0.192CC..Hα-helixtrans-62.4-35.2169.500000113.6F741 I747 L748 L749F741-G745 PolarHBondContact O-N 2.73Å; G745-I747 VanDerWaalsContact C-N 3.35Å; G745-I747 PolarHBondContact O-N 3.06Å; G745-L748 PolarHBondContact O-N 3.26Å; G745-L749 WeakPolarHBondContact O-CG 3.18Å; G745-L749 PolarHBondContact O-N 2.88Å
746N91.6Very high89.9Confident49 Ų4952.8 Ų52.826%0.26224%0.235SC..Hα-helixtrans-65.3-34.4176.1-86.5-10.5000113.2H742 K743 E744 L748 L749 E750H742-N746 PolarHBondContact CE1-ND2 3.41Å; H742-N746 WeakPolarHBondContact O-CB 3.23Å; H742-N746 VanDerWaalsContact O-CG 3.32Å; H742-N746 PolarHBondContact O-N 2.94Å; K743-N746 WeakPolarHBondContact O-CB 3.3Å; K743-N746 PolarHBondContact O-N 2.78Å; E744-N746 VanDerWaalsContact C-N 3.33Å; E744-N746 PolarHBondContact O-N 3.07Å; N746-L748 VanDerWaalsContact C-N 3.29Å; N746-L748 PolarHBondContact O-N 3.02Å; N746-L749 CarbonylContact O-C 3.53Å; N746-L749 PolarHBondContact O-N 3.09Å; N746-E750 WeakPolarHBondContact O-CB 3.45Å; N746-E750 WeakPolarHBondContact O-CG 3.27Å; N746-E750 PolarHBondContact O-N 2.77Å
747I90.8Very high89.6Confident75 Ų7559.4 Ų59.439%0.38527%0.266SS..Hα-helixtrans-59.9-42.6174.7-61.6168.2000110.3V633 L635 K743 E744 G745 E750 A751V633-I747 HydrophobicContact CG1-CG2 3.94Å; L635-I747 HydrophobicContact CD2-CB 4.1Å; L635-I747 HydrophobicContact CD2-CD1 3.87Å; L635-I747 HydrophobicContact CD2-CG2 4.17Å; K743-I747 PolarHBondContact O-N 3.49Å; E744-I747 PolarHBondContact O-N 3.38Å; G745-I747 VanDerWaalsContact C-N 3.35Å; G745-I747 PolarHBondContact O-N 3.06Å; I747-E750 PolarHBondContact O-N 3.3Å; I747-A751 PolarHBondContact O-N 3.48Å
748L91.4Very high89.6Confident0 Ų059.3 Ų59.30%027%0.265CS..Hα-helixtrans-68.3-39.6175.6-175.261.3000112.3I624 L635 L681 I705 L740 G745 N746 E750 A751 L752 V758 V760I624-L748 HydrophobicContact CD1-CD1 4.16Å; I624-L748 HydrophobicContact CG1-CD1 4.38Å; L635-L748 HydrophobicContact CD1-CB 4.12Å; L681-L748 HydrophobicContact CD1-CD2 3.97Å; L681-L748 HydrophobicContact CD2-CD2 4.41Å; I705-L748 HydrophobicContact CD1-CD2 3.78Å; I705-L748 HydrophobicContact CG2-CD2 4.45Å; L740-L748 HydrophobicContact CD1-CD2 4.33Å; G745-L748 PolarHBondContact O-N 3.26Å; N746-L748 VanDerWaalsContact C-N 3.29Å; N746-L748 PolarHBondContact O-N 3.02Å; L748-E750 VanDerWaalsContact C-N 3.31Å; L748-E750 PolarHBondContact O-N 2.81Å; L748-A751 PolarHBondContact O-N 3.04Å; L748-L752 HydrophobicContact CG-CD1 4.37Å; L748-L752 WeakPolarHBondContact O-CB 3.36Å; L748-L752 WeakPolarHBondContact O-CG 3.36Å; L748-L752 PolarHBondContact O-N 3.13Å; L748-V758 HydrophobicContact CD1-CG1 3.98Å; L748-V760 HydrophobicContact CD1-CG1 3.84Å
749L91.2Very high89.5Confident31 Ų3160.5 Ų60.516%0.16227%0.271CS..Hα-helixtrans-71-20.9175.8-71.2170.1000113.8L681 I707 G745 N746 K753L681-L749 HydrophobicContact CD2-CD2 3.61Å; L681-L749 HydrophobicContact CD2-CG 4.34Å; I707-L749 HydrophobicContact CD1-CD1 3.65Å; I707-L749 HydrophobicContact CD1-CD2 4.28Å; I707-L749 HydrophobicContact CD1-CG 3.71Å; G745-L749 WeakPolarHBondContact O-CG 3.18Å; G745-L749 PolarHBondContact O-N 2.88Å; N746-L749 CarbonylContact O-C 3.53Å; N746-L749 PolarHBondContact O-N 3.09Å; L749-K753 WeakPolarHBondContact O-CD 3.38Å; L749-K753 WeakPolarHBondContact O-CE 3.2Å; L749-K753 VanDerWaalsContact O-CG 3.25Å; L749-K753 WeakPolarHBondContact O-CG 3.46Å; L749-K753 PolarHBondContact O-NZ 3.25Å
750E90.3Very high89.6Confident119 Ų11960.3 Ų60.356%0.55627%0.27SS*.Hα-helixtrans-81.7-43.8172.3-76.4174.7-179.500110.7N746 I747 L748 L752 K753 E754N746-E750 WeakPolarHBondContact O-CB 3.45Å; N746-E750 WeakPolarHBondContact O-CG 3.27Å; N746-E750 PolarHBondContact O-N 2.77Å; I747-E750 PolarHBondContact O-N 3.3Å; L748-E750 VanDerWaalsContact C-N 3.31Å; L748-E750 PolarHBondContact O-N 2.81Å; E750-L752 VanDerWaalsContact C-N 3.27Å; E750-L752 PolarHBondContact O-N 3.46Å; E750-K753 PolarHBondContact O-N 3.11Å; E750-E754 PolarHBondContact O-N 2.97Å; E750-E754 VanDerWaalsContact O-N 3.09Å
751A88.8Confident89.5Confident2 Ų261.1 Ų61.12%0.01727%0.274CS..Hα-helixtrans-54.3-42.9170.300000112I624 F629 I747 L748 K753 E754 Y755 V758I624-A751 HydrophobicContact CD1-CB 4.24Å; F629-A751 HydrophobicContact CE2-CB 3.79Å; F629-A751 HydrophobicContact CZ-CB 4.14Å; I747-A751 PolarHBondContact O-N 3.48Å; L748-A751 PolarHBondContact O-N 3.04Å; A751-K753 PolarHBondContact O-N 2.85Å; A751-E754 PolarHBondContact O-N 3.08Å; A751-Y755 WeakPolarHBondContact O-CD2 3.36Å; A751-Y755 PolarHBondContact O-N 2.7Å; A751-V758 HydrophobicContact CB-CG1 4.33Å; A751-V758 HydrophobicContact CB-CG2 4.11Å; A751-V758 WeakPolarHBondContact O-CG2 3.41Å
752L89.3Confident89.6Confident44 Ų4460.4 Ų60.423%0.2327%0.271CS..Hα-helixtrans-69-11.7177.1-78.5165.7000115.1V657 L681 L748 E750 V758V657-L752 HydrophobicContact CB-CD1 4.48Å; V657-L752 HydrophobicContact CB-CD2 4.38Å; V657-L752 HydrophobicContact CG1-CD1 3.94Å; L681-L752 HydrophobicContact CD2-CD1 3.54Å; L748-L752 HydrophobicContact CG-CD1 4.37Å; L748-L752 WeakPolarHBondContact O-CB 3.36Å; L748-L752 WeakPolarHBondContact O-CG 3.36Å; L748-L752 PolarHBondContact O-N 3.13Å; E750-L752 VanDerWaalsContact C-N 3.27Å; E750-L752 PolarHBondContact O-N 3.46Å; L752-V758 HydrophobicContact CD2-CB 3.76Å; L752-V758 HydrophobicContact CD2-CG2 3.81Å; L752-V758 HydrophobicContact CG-CB 4.16Å; L752-V758 HydrophobicContact CG-CG2 4.02Å
753K88.4Confident89.5Confident156 Ų15658.7 Ų58.768%0.67826%0.263SS*.Hα-helixtrans-95.1-32.7173-67.6160.7-164.4148.90112L749 E750 A751L749-K753 WeakPolarHBondContact O-CD 3.38Å; L749-K753 WeakPolarHBondContact O-CE 3.2Å; L749-K753 VanDerWaalsContact O-CG 3.25Å; L749-K753 WeakPolarHBondContact O-CG 3.46Å; L749-K753 PolarHBondContact O-NZ 3.25Å; E750-K753 PolarHBondContact O-N 3.11Å; A751-K753 PolarHBondContact O-N 2.85Å
754E86.1Confident89.3Confident138 Ų13855.9 Ų55.965%0.64525%0.253SS*.Hα-helixtrans-86.6-37.2-177.2-169.3171.9-135.500112.3E750 A751E750-E754 PolarHBondContact O-N 2.97Å; E750-E754 VanDerWaalsContact O-N 3.09Å; A751-E754 PolarHBondContact O-N 3.08Å
755Y85.8Confident88.9Confident65 Ų6560.3 Ų60.326%0.25527%0.272SS..  trans-115.6136-177.7-51.6-77.3000111.2P628 F629 A751 E757P628-Y755 HydrophobicContact CG-CE1 4.23Å; P628-Y755 HydrophobicContact CG-CE2 4.36Å; F629-Y755 AromaticContact CE2-CD2 3.82Å; F629-Y755 HydrophobicContact CE2-CD2 3.82Å; F629-Y755 AromaticContact CE2-CE2 3.68Å; F629-Y755 HydrophobicContact CE2-CE2 3.68Å; F629-Y755 HydrophobicContact CZ-CD2 4.35Å; F629-Y755 AromaticContact CZ-CE2 3.79Å; F629-Y755 HydrophobicContact CZ-CE2 3.79Å; A751-Y755 WeakPolarHBondContact O-CD2 3.36Å; A751-Y755 PolarHBondContact O-N 2.7Å; Y755-E757 VanDerWaalsContact C-N 3.33Å; Y755-E757 PolarHBondContact O-N 2.82Å
756R74.9Confident88.4Confident254 Ų25462.7 Ų62.796%0.95829%0.292SS*.SBendtrans-67.8-30.4-176.4-78.2-175168.7-171-3.9114.3
757E84.6Confident87.7Confident144 Ų14465 Ų6567%0.67330%0.297SS*.  trans-134.3104.5-174.8-71.1171.717800107.4F656 Y755F656-E757 HydrophobicContact CD1-CB 4.08Å; F656-E757 HydrophobicContact CE1-CB 3.94Å; Y755-E757 VanDerWaalsContact C-N 3.33Å; Y755-E757 PolarHBondContact O-N 2.82Å
758V91.4Very high86.1Confident2 Ų269.2 Ų69.21%0.01232%0.32CS..  trans-104.6118.6177.4-179.40000108.4I624 F656 V657 L748 A751 L752 V760I624-V758 HydrophobicContact CG2-CG1 3.84Å; F656-V758 WeakPolarHBondContact CA-O 3.4Å; V657-V758 PolarHBondContact N-O 3.26Å; L748-V758 HydrophobicContact CD1-CG1 3.98Å; A751-V758 HydrophobicContact CB-CG1 4.33Å; A751-V758 HydrophobicContact CB-CG2 4.11Å; A751-V758 WeakPolarHBondContact O-CG2 3.41Å; L752-V758 HydrophobicContact CD2-CB 3.76Å; L752-V758 HydrophobicContact CD2-CG2 3.81Å; L752-V758 HydrophobicContact CG-CB 4.16Å; L752-V758 HydrophobicContact CG-CG2 4.02Å; V758-V760 HydrophobicContact CG1-CG1 4.38Å
759E92.9Very high84.1Confident29 Ų2978.6 Ų78.614%0.13636%0.356CS..EExtended strand (participates in β ladder)trans-107133.8179.4-164.1-170.5-163.200109.6V625 S626 R654 G655 F656V625-E759 HydrophobicContact CG2-CB 3.89Å; V625-E759 HydrophobicContact CG2-CG 3.74Å; V625-E759 WeakPolarHBondContact CG2-O 3.18Å; V625-E759 WeakPolarHBondContact CG2-OE2 3.23Å; V625-E759 PolarHBondContact N-O 2.85Å; S626-E759 PolarHBondContact N-O 2.88Å; S626-E759 PolarHBondContact OG-N 2.94Å; R654-E759 HydrophobicContact CG-CG 4.34Å; R654-E759 WeakPolarHBondContact CG-OE1 3.16Å; R654-E759 IonicContact CZ-OE1 2.76Å; R654-E759 IonicContact CZ-OE2 2.79Å; R654-E759 IonicContact NE-OE1 2.69Å; R654-E759 PolarHBondContact NE-OE1 3.01Å; R654-E759 IonicContact NE-OE2 2.75Å; R654-E759 PolarHBondContact NE-OE2 3.24Å; R654-E759 IonicContact NH2-OE1 3.4Å; R654-E759 PolarHBondContact NH2-OE1 3.19Å; R654-E759 IonicContact NH2-OE2 3.68Å; R654-E759 PolarHBondContact NH2-OE2 3.49Å; G655-E759 WeakPolarHBondContact O-CA 3.32Å; F656-E759 HydrophobicContact CD1-CB 3.84Å; F656-E759 HydrophobicContact CD1-CG 4.24Å; F656-E759 HydrophobicContact CE1-CB 3.84Å; F656-E759 HydrophobicContact CE1-CG 4.26Å
760V94.4Very high81.6Confident0 Ų081 Ų810%039%0.388CS..EExtended strand (participates in β ladder)trans-126.7152.5178.5-56.50000112I622 Q623 I624 R654 G655 V657 I679 I705 L748 V758 L762I622-V760 HydrophobicContact CG2-CB 4.05Å; I622-V760 HydrophobicContact CG2-CG1 4.27Å; I622-V760 HydrophobicContact CG2-CG2 4.38Å; Q623-V760 CarbonylContact O-C 3.58Å; Q623-V760 WeakPolarHBondContact O-CA 3.13Å; I624-V760 HydrophobicContact CG1-CG1 4.27Å; R654-V760 WeakPolarHBondContact CA-O 3.36Å; G655-V760 PolarHBondContact N-O 3.09Å; G655-V760 PolarHBondContact O-N 3.14Å; V657-V760 HydrophobicContact CG2-CB 4.15Å; V657-V760 HydrophobicContact CG2-CG1 3.67Å; V657-V760 HydrophobicContact CG2-CG2 3.42Å; V657-V760 VanDerWaalsContact CG2-CG2 3.42Å; I679-V760 HydrophobicContact CD1-CG2 3.61Å; I705-V760 HydrophobicContact CD1-CG2 4.2Å; L748-V760 HydrophobicContact CD1-CG1 3.84Å; V758-V760 HydrophobicContact CG1-CG1 4.38Å; V760-L762 HydrophobicContact CG2-CD2 4.01Å
761L92.8Very high78.9Confident16 Ų1679.6 Ų79.68%0.08440%0.397CS..EExtended strand (participates in β ladder)trans-106.1123.2166.2174.765.4000108.9I622 Q623 V625 R654 R767I622-L761 WeakPolarHBondContact CA-O 3.32Å; Q623-L761 HydrophobicContact CB-CB 4.47Å; Q623-L761 PolarHBondContact N-O 3.45Å; Q623-L761 PolarHBondContact O-N 2.82Å; V625-L761 HydrophobicContact CG1-CB 4Å; R654-L761 HydrophobicContact CB-CD1 4.13Å; L761-R767 HydrophobicContact CD2-CG 4.49Å
762L92.7Very high76.2Confident0 Ų087 Ų870%044%0.436CS..EExtended strand (participates in β ladder)trans-91.8117.8166.7-42.9-178.9000107.8I622 L646 G652 V653 I679 I705 P736 L738 V760I622-L762 HydrophobicContact CD1-CD2 4.16Å; I622-L762 HydrophobicContact CG1-CD2 3.87Å; I622-L762 HydrophobicContact CG2-CD2 4.16Å; L646-L762 HydrophobicContact CD1-CB 4.02Å; G652-L762 WeakPolarHBondContact CA-O 3.41Å; V653-L762 HydrophobicContact CB-CB 4.47Å; V653-L762 PolarHBondContact N-O 2.85Å; V653-L762 PolarHBondContact O-N 3.33Å; I679-L762 HydrophobicContact CD1-CD1 4.07Å; I679-L762 HydrophobicContact CD1-CD2 4.33Å; I679-L762 HydrophobicContact CD1-CG 3.95Å; I679-L762 HydrophobicContact CG1-CD1 4.49Å; I679-L762 HydrophobicContact CG2-CD1 4.3Å; I705-L762 HydrophobicContact CD1-CD2 4Å; I705-L762 HydrophobicContact CG1-CD2 4.06Å; P736-L762 HydrophobicContact CG-CD1 4.41Å; L738-L762 HydrophobicContact CD1-CB 4.04Å; L738-L762 HydrophobicContact CD1-CD2 4.23Å; V760-L762 HydrophobicContact CG2-CD2 4.01Å
763S90.2Very high73.5Confident1 Ų191.2 Ų91.21%0.00746%0.463CS..EExtended strand (participates in β ladder)trans-140.9167.9-176.2580000112.4A621 K765A621-S763 PolarHBondContact N-O 3.47Å; A621-S763 PolarHBondContact O-N 2.85Å; S763-K765 WeakPolarHBondContact CB-O 3.28Å; S763-K765 PolarHBondContact OG-O 3.32Å
764D84.8Confident70.6Confident33 Ų3393 Ų9318%0.17647%0.473CS..SBendtrans-66.8-63.9173.7-16510.5000110.6R620 A621 S647R620-D764 WeakPolarHBondContact CA-O 3.45Å; R620-D764 WeakPolarHBondContact CD-OD1 3.38Å; R620-D764 IonicContact CZ-OD1 2.83Å; R620-D764 IonicContact NE-OD1 3.1Å; R620-D764 IonicContact NH1-OD1 3.63Å; R620-D764 PolarHBondContact NH1-OD1 3.48Å; R620-D764 IonicContact NH2-OD1 3.41Å; A621-D764 PolarHBondContact N-O 2.77Å; S647-D764 VanDerWaalsContact CA-OD2 3.28Å; S647-D764 WeakPolarHBondContact CA-OD2 3.49Å; S647-D764 WeakPolarHBondContact CB-OD2 3.46Å
765K83.3Confident67.8Low108 Ų10895 Ų9547%0.4748%0.483SS..SBendtrans-107.4162.3173-59.2173.7-172.3171.60110.2S763 E883S763-K765 WeakPolarHBondContact CB-O 3.28Å; S763-K765 PolarHBondContact OG-O 3.32Å; K765-E883 WeakPolarHBondContact CE-OE1 3.18Å; K765-E883 IonicContact NZ-OE1 2.75Å; K765-E883 PolarHBondContact NZ-OE1 2.8Å
766A80.6Confident65Low51 Ų51101.1 Ų101.142%0.42151%0.514SS..  trans-66.4147.4168.800000110.2A621 V634A621-A766 HydrophobicContact CB-CB 4.28Å; V634-A766 HydrophobicContact CG1-CB 3.73Å; V634-A766 HydrophobicContact CG2-CB 4.15Å
767R77.8Confident62.6Low96 Ų9698 Ų9836%0.36251%0.51SS..  trans-108.8135.1179.6-62.8-171.3178.9163.22.2112Q623 S650 T651 L761Q623-R767 PolarHBondContact NE2-O 3.48Å; S650-R767 PolarHBondContact O-NH2 2.89Å; T651-R767 PolarHBondContact O-NH1 3.44Å; T651-R767 PolarHBondContact O-NH2 3.16Å; L761-R767 HydrophobicContact CD2-CG 4.49Å
768D56.1Low59.9Low164 Ų16499.9 Ų99.988%0.87752%0.519SS*.  trans-82.7152.6172.2-73.8-48.2000112.4G770D768-G770 PolarHBondContact O-N 3.14Å
769R49.4Very low56.7Low198 Ų198106.2 Ų106.275%0.74755%0.553SS**SBendtrans-82.797.8178.7-81.7178.6141.4-138.8-10.3110.8F630F630-R769 PolarHBondContact O-NE 2.76Å; F630-R769 VanDerWaalsContact O-NE 3.14Å
770G39.2Very low53.3Low81 Ų81110.5 Ų110.584%0.83559%0.585SS**SBendtrans-157.9-21.6173.300000117.8D768D768-G770 PolarHBondContact O-N 3.14Å
771A34.5Very low50Low90 Ų90117.6 Ų117.674%0.74462%0.618SS**SBendtrans-95.3-38.3-167.900000115.8V773A771-V773 PolarHBondContact O-N 2.89Å
772D32.2Very low46.7Very low158 Ų158122.7 Ų122.785%0.84565%0.65SS**  trans-96.675.4-167.5-63.5-41.3000113.4
773V31.7Very low43.5Very low131 Ų131132.4 Ų132.479%0.79470%0.695SS**  trans-141.883.5154.5-171.30000110A771A771-V773 PolarHBondContact O-N 2.89Å
774Q27.5Very low40.3Very low193 Ų193136.6 Ų136.690%0.90273%0.73SS**  trans-128.5136.7151-74.3-169.8-26.600107.5
775E28Very low37.5Very low181 Ų181142.1 Ų142.185%0.84677%0.765SS**  trans-84.9139.5-171.7-64173.7124.300110.5E777E775-E777 PolarHBondContact O-N 3.47Å
776E25.8Very low34.6Very low193 Ų193143.2 Ų143.290%0.90278%0.781SS**  trans-77.487.1178.9-67.3-179.2132.300110.9E778E776-E778 PolarHBondContact O-N 2.9Å
777E24.8Very low32.5Very low190 Ų190146 Ų14689%0.88880%0.795SS**  trans-76.695.2163.8-73.7-161.3131.700110.6E775 D779E775-E777 PolarHBondContact O-N 3.47Å; E777-D779 PolarHBondContact O-N 3.27Å
778E27.1Very low29.9Very low182 Ų182148 Ų14885%0.8582%0.818SS**  trans-70.684.1169.9-71-166.4119.600112.2E776 C780E776-E778 PolarHBondContact O-N 2.9Å; E778-C780 PolarHBondContact O-N 2.98Å
779D24.4Very low28.4Very low136 Ų136144.3 Ų144.373%0.72781%0.805SS**  trans-79.196.4165.8-169.85.6000110.6E777 Q781E777-D779 PolarHBondContact O-N 3.27Å; D779-Q781 PolarHBondContact OD1-NE2 3.32Å; D779-Q781 VanDerWaalsContact OD1-NE2 3.15Å
780C22.2Very low27.1Very low119 Ų119144.1 Ų144.180%0.80481%0.81SS**  trans-106.3103.9-173-155.40000112.6E778E778-C780 PolarHBondContact O-N 2.98Å
781Q24.1Very low26.5Very low149 Ų149149.1 Ų149.170%0.69681%0.812SS**  trans-135.8131.6177.3-75.9-176.764.500109.7D779D779-Q781 PolarHBondContact OD1-NE2 3.32Å; D779-Q781 VanDerWaalsContact OD1-NE2 3.15Å
782T24.6Very low26.8Very low123 Ų123150.1 Ų150.176%0.75581%0.811SS**  cis-154.8154.70.328.40000109.8
783E24.8Very low26.4Very low203 Ų203150.2 Ų150.295%0.94981%0.811SS**  -156.1158.4128.3-121.5179.8-155.700110.7
784A24Very low26.1Very low90 Ų90148 Ų14874%0.74480%0.801SS**  trans-113.4137.3-15700000115.2
785T24.9Very low26Very low148 Ų148147.1 Ų147.191%0.90880%0.797SS**  trans-161.2142.5137.82.60000113.1
786T22.5Very low25.9Very low132 Ų132142.8 Ų142.881%0.8179%0.787SS**  trans-122177.2178.335.50000109.7
787P36.8Very low25.9Very low109 Ų109141.8 Ų141.871%0.70878%0.783SS**  cis-132.4172.5-25.433.4-16.8000113.6
788T24.1Very low25.9Very low137 Ų137140.6 Ų140.684%0.8478%0.779SS**  trans157151.814435.10000110.1
789S23.2Very low25.7Very low88 Ų88136.6 Ų136.662%0.61577%0.771SS**  cis-174.9163.8-21.847.50000110
790F23.7Very low25.9Very low194 Ų194136 Ų13685%0.85177%0.773SS**  trans82.798.8169.4-65.5-77.3000120
791E25.7Very low26.2Very low186 Ų186138.6 Ų138.687%0.86977%0.773SS**  6.9164.1123.2-75.7-165.1147.900123.6
792P41.7Very low26.4Very low111 Ų111139.5 Ų139.572%0.72178%0.777SS**  trans-126.5-179.1-149.145.4-31.8000116.2
793D23.6Very low26.6Very low159 Ų159140.2 Ų140.285%0.8578%0.776SS**  trans-170.4149.6148.5-106.5-28.6000106.9
794S24.7Very low26.6Very low85 Ų85137 Ų13759%0.59477%0.765SS**  cis-160.9-163.8-5.350.60000106.8
795Q26.3Very low26.9Very low174 Ų174140.8 Ų140.881%0.81377%0.767SS**  cis-161.6-150.513.4-146.4164.6113.800111.2
796S25.8Very low26.9Very low91 Ų91139.2 Ų139.264%0.63676%0.762SS**  trans-79.4171.7-179.9480000116.4
797Q25.5Very low27.2Very low172 Ų172137.3 Ų137.380%0.80476%0.76SS**  cis174.5168.3-23.1-165.5176.610.500107.8
798M24.1Very low27.9Very low165 Ų165137.7 Ų137.781%0.81376%0.762SS**  trans68.4168.6167.4-68.4176.663.700117.7
799S24.2Very low27.9Very low98 Ų98140.3 Ų140.369%0.68577%0.765SS**  177.3164.6-57.655.20000109.2
800T27.5Very low28.2Very low124 Ų124145 Ų14576%0.76178%0.777SS**  trans-82.5154.6-173.5450000115.7
801E28.3Very low28.3Very low172 Ų172142.2 Ų142.280%0.80478%0.776SS**  171138.4122.4-93.4168.7-174.700114.5
802E29.4Very low28.4Very low169 Ų169139.5 Ų139.579%0.7977%0.772SS**  trans54.6161143.7-63.6-159.5158.400122.6
803L28.6Very low28.6Very low138 Ų138139.9 Ų139.972%0.72378%0.775SS**  cis-156.4-158.44.7-131.4168.8000112.2
804D24.9Very low28.9Very low136 Ų136136.2 Ų136.273%0.72777%0.766SS**  trans78146.7166.6-69.5-3.8000120.7
805E29.4Very low29.1Very low169 Ų169139.8 Ų139.879%0.7977%0.774SS**  cis-165159.2-27.3-154.1-168.8-162.300111
806S25.6Very low29.3Very low114 Ų114138.8 Ų138.880%0.79777%0.769SS**  trans81.9156154.482.10000123.1
807A27.7Very low29.5Very low93 Ų93141.9 Ų141.977%0.76977%0.773SS**  trans-163.8-172.2175.300000107.6
808P51.1Low29.5Very low116 Ų116139.1 Ų139.175%0.75377%0.768SS**  cis-132.2-171.3-1143.9-27.5000113.5
809E25.2Very low29.6Very low193 Ų193136.2 Ų136.290%0.90276%0.764SS**  179.8162.1127.3-103.3-175175.700113.1
810E28.7Very low31.1Very low186 Ų186137.1 Ų137.187%0.86977%0.768SS**  trans-105.3174.1-179.9-59.4179.6107.300112.6
811V25.3Very low31.2Very low136 Ų136137.3 Ų137.382%0.82477%0.768SS**  168.5139.6128.6152.40000113
812T29.7Very low31.4Very low129 Ų129132.9 Ų132.979%0.79176%0.761SS**  trans-133.4159.1159.662.30000108
813P45.1Very low31.4Very low119 Ų119132.7 Ų132.777%0.77376%0.76SS**  -164.6-162.788.943.9-21.3000117.2
814A29.3Very low31.4Very low82 Ų82131.6 Ų131.668%0.67876%0.759SS**  trans77.612616000000119
815Q30.1Very low31.4Very low160 Ų160132.4 Ų132.475%0.74876%0.762SS**  83.7149.250.2-68.8-179.8-71.600113.9
816E29.9Very low31.3Very low153 Ų153131.5 Ų131.572%0.71576%0.755SS**  cis-146.3-171.6-0.4-146.198.2-97.300107.6
817E29.1Very low31.4Very low156 Ų156131.8 Ų131.873%0.72974%0.744SS**  cis-144-149.14.5-155-145.313500107.1
818V25.3Very low31.3Very low114 Ų114135.3 Ų135.369%0.69174%0.744SS**  cis-151.3153.813.9-1710000109.1
819S26.6Very low30.2Very low103 Ų103136.5 Ų136.572%0.7274%0.74SS**  trans-110.4-136.6172.5-48.30000111.9
820P56.7Low30.2Very low118 Ų118134.2 Ų134.277%0.76673%0.729SS**  cis-118.3-176-11.529.3-4.3000112.5
821V29.4Very low30.1Very low128 Ų128131.4 Ų131.478%0.77671%0.714SS**  -176.2156.955.2169.80000105.9
822A31.7Very low30.2Very low79 Ų79129.2 Ų129.265%0.65371%0.711SS**  cis-171.2-158.1-26.800000105.2
823E29.2Very low30Very low165 Ų165129.7 Ų129.777%0.77171%0.713SS**  cis-163.11272.6-153.6160.3-71.800111.2
824V29.7Very low29.3Very low115 Ų115130.8 Ų130.870%0.69771%0.712SS**  trans47.4131.1141.4-166.80000121.1
825I25.1Very low30.2Very low153 Ų153131 Ų13179%0.78571%0.707SS**  -167.612186.8-76.2169.2000106.4
826K26.9Very low30.1Very low150 Ų150131.9 Ų131.965%0.65271%0.711SS**  63.4143.784.9-75.3-178.5149.5-131.70115.4
827E26.8Very low30Very low119 Ų119128.3 Ų128.356%0.55671%0.707SS**  cis-162.81535.1-124.9157.517200112.8
828E26.6Very low29.9Very low168 Ų168129.3 Ų129.379%0.78571%0.712SS**  trans53.2173147.8-71.1163.5-172.900122.3
829E27.6Very low29.9Very low140 Ų140129.5 Ų129.565%0.65471%0.714SS**  -157.6-178.2-67.5-103.7-12372.200106.9K831E829-K831 IonicContact OE1-NZ 2.69Å; E829-K831 PolarHBondContact OE1-NZ 3.09Å; E829-K831 IonicContact OE2-NZ 3.13Å; E829-K831 PolarHBondContact OE2-NZ 3.3Å
830E26.3Very low29.9Very low146 Ų146129.3 Ų129.368%0.68272%0.719SS**  cis-148.4152.516.3-143.3-159.3165.700114.8
831K26Very low28.6Very low126 Ų126135.1 Ų135.155%0.54873%0.725SS.*  trans6129.8147.4-65.4176.4-146.869.50121E829E829-K831 IonicContact OE1-NZ 2.69Å; E829-K831 PolarHBondContact OE1-NZ 3.09Å; E829-K831 IonicContact OE2-NZ 3.13Å; E829-K831 PolarHBondContact OE2-NZ 3.3Å
832A26.8Very low28.9Very low91 Ų91135.3 Ų135.375%0.75273%0.729SS**  90.1164.593.400000113.9
833V25.9Very low28.7Very low138 Ų138139.1 Ų139.184%0.83673%0.731SS**  cis-148.2155.431.21720000111.6
834D30.7Very low28.6Very low142 Ų142138.2 Ų138.276%0.75973%0.727SS**  trans-128.6150.9166-17341000107.6
835P46.9Very low28.3Very low88 Ų88141.5 Ų141.557%0.57173%0.734SS**  -161.7175.490.745.2-24.9000119.2
836Q28.5Very low28.3Very low178 Ų178144.5 Ų144.583%0.83274%0.736SS**  trans73.3147.6150.9-75.3167.37.600119.7
837A27.8Very low28.3Very low77 Ų77143.1 Ų143.164%0.63674%0.735SS**  cis-169.7161.5-13.200000112.7
838E27.3Very low28.2Very low177 Ų177143 Ų14383%0.82775%0.748SS**  trans62.5161156.5-72.6-176.1-161.100119.1
839T25.6Very low28.2Very low118 Ų118143 Ų14372%0.72475%0.748SS**  cis-153.3161.7-6.84.80000112.3
840A27.3Very low28.1Very low100 Ų100145.5 Ų145.583%0.82676%0.757SS**  trans70.2151.3147.500000124
841R28.6Very low28Very low239 Ų239144.2 Ų144.290%0.90276%0.759SS**  trans-104.5166.4163.1-64.8178175.4173.9-2.9110
842P35.8Very low28Very low132 Ų132147.9 Ų147.986%0.85778%0.778SS**  -143.2-153.6113.638-21.8000115.1
843K26.6Very low27.8Very low160 Ų160151.8 Ų151.870%0.69678%0.781SS**  trans-121.9167.8-153-45.817175.2-146.30115
844E26.7Very low28.8Very low146 Ų146149.3 Ų149.368%0.68277%0.768SS**  trans54.4125.6140.8-72.3155.216700123.5
845E24.2Very low28.5Very low184 Ų184154.3 Ų154.386%0.8678%0.776SS**  173.4139.6122.2-90.2179169.200107.7
846R25.4Very low27.4Very low215 Ų215153.3 Ų153.381%0.81178%0.781SS**  62.7138.564.7-77.3-159.6177.1-159.22114.2
847D26Very low27.2Very low121 Ų121152.4 Ų152.465%0.64778%0.782SS**  cis-139.2162.6-2.4-83.1-47.1000109.1
848S25.2Very low27.1Very low117 Ų117154.6 Ų154.682%0.81879%0.788SS**  157.916589.446.60000108.9
849E27Very low27.1Very low167 Ų167153.9 Ų153.978%0.7879%0.79SS**  cis172154.5-25-161.1-169.6-153.500105.8
850K25.4Very low27.2Very low194 Ų194153 Ų15384%0.84379%0.788SS**  trans111.794.1-178.3-68164.9-176.4169.80112.7
851T24.5Very low27.5Very low119 Ų119153.9 Ų153.973%0.7379%0.789SS**  cis78.696.934.2-38.30000114.2
852Q25.2Very low27.8Very low202 Ų202148 Ų14894%0.94478%0.784SS**  trans-148.7147.4144.6-115.4175.52.200110
853E23.8Very low28.1Very low174 Ų174147.7 Ų147.781%0.81377%0.771SS**  trans-149.2-179.5-163.4-129.2-168.6-138.600106.7
854P46.2Very low28.9Very low86 Ų86142.5 Ų142.556%0.55876%0.755SS**  cis-138.7-174.1-14.839.4-21.4000114.8
855R25Very low29.9Very low247 Ų247140.6 Ų140.693%0.93275%0.753SS**  trans69.2148.5166.6-55.2168.6-175.6-178.2-1.1115
856G23.7Very low30.7Very low67 Ų67137.6 Ų137.669%0.69174%0.743SS**  cis168164.63.900000106
857D23.8Very low31.5Very low159 Ų159131.8 Ų131.885%0.8573%0.725SS**  cis-146.3173.85.9-95.6-47.7000109.6
858T26.3Very low32.2Very low123 Ų123130.3 Ų130.376%0.75572%0.716SS**  trans0.9132.9161.357.20000120.2
859D26.3Very low32.9Very low162 Ų162128.6 Ų128.687%0.86670%0.697SS**  -147.5159101.8-140.5-24.6000111.2
860S29.1Very low33.8Very low99 Ų99122.8 Ų122.869%0.69268%0.678SS**  trans-150.1114.6-172.161.20000114.1
861S32.5Very low34.6Very low119 Ų119117.4 Ų117.483%0.83266%0.658SS**  trans-105.483.2173590000111.4Q863S861-Q863 PolarHBondContact O-N 3.03Å
862S35.4Very low35.6Very low114 Ų114120.1 Ų120.180%0.79766%0.655SS**  trans-77.1103.7163.154.40000108.9
863Q42Very low36.3Very low127 Ų127117.4 Ų117.459%0.59364%0.637SS**  trans-58.6145.8172-73.4174.2-80.600110.4S861S861-Q863 PolarHBondContact O-N 3.03Å
864S42.9Very low37.2Very low50 Ų50116.2 Ų116.235%0.3563%0.631SS.*  trans-78.9155.6179.865.40000111.8D866 E867 L868S864-D866 PolarHBondContact O-N 3.19Å; S864-E867 WeakPolarHBondContact CB-OE2 3.42Å; S864-E867 PolarHBondContact N-OE2 3.33Å; S864-E867 PolarHBondContact O-N 2.97Å; S864-E867 VanDerWaalsContact OG-CD 3.31Å; S864-E867 WeakPolarHBondContact OG-CG 3.42Å; S864-E867 PolarHBondContact OG-N 3.48Å; S864-E867 PolarHBondContact OG-OE2 3.31Å; S864-L868 PolarHBondContact O-N 3.05Å
865V47.3Very low37Very low106 Ų106117.4 Ų117.464%0.64263%0.633SS**Hα-helixtrans-63-30.2177-177.70000110.9L868 L869V865-L868 PolarHBondContact O-N 3.41Å; V865-L869 HydrophobicContact CG1-CD1 4.02Å; V865-L869 HydrophobicContact CG1-CG 4.36Å; V865-L869 WeakPolarHBondContact O-CB 3.09Å; V865-L869 VanDerWaalsContact O-CG 3.25Å; V865-L869 WeakPolarHBondContact O-CG 3.22Å; V865-L869 PolarHBondContact O-N 2.81Å
866D41.3Very low37.7Very low121 Ų121109.5 Ų109.565%0.64761%0.608SS**Hα-helixtrans-68.1-32.2176.6-66.8-54.9000113.5S864 A870S864-D866 PolarHBondContact O-N 3.19Å; D866-A870 PolarHBondContact O-N 3.23Å
867E41.9Very low38.6Very low94 Ų94112.9 Ų112.944%0.43961%0.606SS.*Hα-helixtrans-70.8-46.1172.2-72.1161.9125.100110.9S864 L869 A870 D871S864-E867 WeakPolarHBondContact CB-OE2 3.42Å; S864-E867 PolarHBondContact N-OE2 3.33Å; S864-E867 PolarHBondContact O-N 2.97Å; S864-E867 VanDerWaalsContact OG-CD 3.31Å; S864-E867 WeakPolarHBondContact OG-CG 3.42Å; S864-E867 PolarHBondContact OG-N 3.48Å; S864-E867 PolarHBondContact OG-OE2 3.31Å; E867-L869 PolarHBondContact O-N 3.16Å; E867-A870 WeakPolarHBondContact O-CA 3.38Å; E867-A870 VanDerWaalsContact O-CB 3.3Å; E867-A870 WeakPolarHBondContact O-CB 3.48Å; E867-A870 PolarHBondContact O-N 3.38Å; E867-D871 PolarHBondContact O-N 3.46Å
868L41.8Very low39.2Very low89 Ų89107.8 Ų107.847%0.46659%0.586SS.*Hα-helixtrans-60.4-34.2174.6-75.3165.9000112.5S864 V865 A870 W872S864-L868 PolarHBondContact O-N 3.05Å; V865-L868 PolarHBondContact O-N 3.41Å; L868-A870 VanDerWaalsContact C-N 3.35Å; L868-W872 WeakPolarHBondContact O-CB 3.37Å; L868-W872 PolarHBondContact O-N 3.34Å; L868-W872 VanDerWaalsContact O-N 3.12Å
869L39.4Very low39.5Very low81 Ų81109.2 Ų109.242%0.42458%0.582SS.*Hα-helixtrans-75.8-20.2172.3-71.5170.5000112.9V865 E867 R873V865-L869 HydrophobicContact CG1-CD1 4.02Å; V865-L869 HydrophobicContact CG1-CG 4.36Å; V865-L869 WeakPolarHBondContact O-CB 3.09Å; V865-L869 VanDerWaalsContact O-CG 3.25Å; V865-L869 WeakPolarHBondContact O-CG 3.22Å; V865-L869 PolarHBondContact O-N 2.81Å; E867-L869 PolarHBondContact O-N 3.16Å; L869-R873 WeakPolarHBondContact O-CG 3.42Å; L869-R873 PolarHBondContact O-N 3.03Å; L869-R873 PolarHBondContact O-NE 3.26Å; L869-R873 PolarHBondContact O-NH2 3.36Å; L869-R873 VanDerWaalsContact O-NH2 3.07Å
870A45.4Very low39.8Very low45 Ų45106.5 Ų106.537%0.37256%0.563SS.*Hα-helixtrans-73.5-52.7171.700000110.4D866 E867 L868 W872 R873 E874D866-A870 PolarHBondContact O-N 3.23Å; E867-A870 WeakPolarHBondContact O-CA 3.38Å; E867-A870 VanDerWaalsContact O-CB 3.3Å; E867-A870 WeakPolarHBondContact O-CB 3.48Å; E867-A870 PolarHBondContact O-N 3.38Å; L868-A870 VanDerWaalsContact C-N 3.35Å; A870-W872 VanDerWaalsContact C-N 3.3Å; A870-W872 PolarHBondContact O-N 3.25Å; A870-R873 PolarHBondContact O-N 3.05Å; A870-E874 PolarHBondContact O-N 3.3Å
871D43Very low40Very low81 Ų81106.2 Ų106.243%0.43355%0.551SS.*Hα-helixtrans-51.7-49.5173.5-68.30.1000110.5E867 R873 E874 D875E867-D871 PolarHBondContact O-N 3.46Å; D871-R873 PolarHBondContact O-N 2.83Å; D871-R873 VanDerWaalsContact O-N 3.12Å; D871-E874 PolarHBondContact O-N 2.98Å; D871-E874 VanDerWaalsContact O-N 3.09Å; D871-D875 PolarHBondContact O-N 3.09Å
872W44.2Very low40Very low176 Ų176106.4 Ų106.467%0.66754%0.54SS*.Hα-helixtrans-62.2-19.1177.5-107.779.9000115.2L868 A870 L876L868-W872 WeakPolarHBondContact O-CB 3.37Å; L868-W872 PolarHBondContact O-N 3.34Å; L868-W872 VanDerWaalsContact O-N 3.12Å; A870-W872 VanDerWaalsContact C-N 3.3Å; A870-W872 PolarHBondContact O-N 3.25Å; W872-L876 HydrophobicContact CE3-CD1 4.26Å; W872-L876 HydrophobicContact CZ3-CD1 4.38Å; W872-L876 WeakPolarHBondContact O-CB 3.39Å
873R41.3Very low39.7Very low146 Ų146105.6 Ų105.655%0.55152%0.523SS*.Hα-helixtrans-88-37173.3-79.2175.5-70.7-124.7-3.4111.2L869 A870 D871 L876 E877L869-R873 WeakPolarHBondContact O-CG 3.42Å; L869-R873 PolarHBondContact O-N 3.03Å; L869-R873 PolarHBondContact O-NE 3.26Å; L869-R873 PolarHBondContact O-NH2 3.36Å; L869-R873 VanDerWaalsContact O-NH2 3.07Å; A870-R873 PolarHBondContact O-N 3.05Å; D871-R873 PolarHBondContact O-N 2.83Å; D871-R873 VanDerWaalsContact O-N 3.12Å; R873-L876 CarbonylContact O-C 3.59Å; R873-L876 PolarHBondContact O-N 2.86Å; R873-E877 PolarHBondContact O-N 3.23Å
874E42.2Very low39.1Very low148 Ų148106 Ų10669%0.69252%0.523SS*.Hα-helixtrans-67.7-42.3177.9-156.6157.2-149.800110.9A870 D871 L876 E877 A878A870-E874 PolarHBondContact O-N 3.3Å; D871-E874 PolarHBondContact O-N 2.98Å; D871-E874 VanDerWaalsContact O-N 3.09Å; E874-L876 VanDerWaalsContact C-N 3.31Å; E874-L876 PolarHBondContact O-N 3.43Å; E874-E877 PolarHBondContact O-N 2.86Å; E874-A878 PolarHBondContact O-N 3.19Å
875D42.3Very low38.6Very low112 Ų112109.6 Ų109.660%0.59954%0.538SS*.Hα-helixtrans-58.2-40.1169.7-84.6-21.9000112.5D871 E877 A878 F879D871-D875 PolarHBondContact O-N 3.09Å; D875-E877 VanDerWaalsContact C-N 3.33Å; D875-A878 PolarHBondContact O-N 2.75Å; D875-F879 WeakPolarHBondContact O-CB 3.39Å; D875-F879 PolarHBondContact O-N 2.78Å
876L39.2Very low37.8Very low80 Ų80112.8 Ų112.842%0.41955%0.546SS..Hα-helixtrans-80.5-13.6-177.7-137156.8000112.6W872 R873 E874 K880W872-L876 HydrophobicContact CE3-CD1 4.26Å; W872-L876 HydrophobicContact CZ3-CD1 4.38Å; W872-L876 WeakPolarHBondContact O-CB 3.39Å; R873-L876 CarbonylContact O-C 3.59Å; R873-L876 PolarHBondContact O-N 2.86Å; E874-L876 VanDerWaalsContact C-N 3.31Å; E874-L876 PolarHBondContact O-N 3.43Å; L876-K880 VanDerWaalsContact O-CD 3.25Å; L876-K880 WeakPolarHBondContact O-CD 3.26Å; L876-K880 WeakPolarHBondContact O-CE 3.21Å; L876-K880 VanDerWaalsContact O-CG 3.27Å; L876-K880 WeakPolarHBondContact O-CG 3.44Å; L876-K880 PolarHBondContact O-NZ 3.42Å
877E41.9Very low37.1Very low139 Ų139115 Ų11565%0.6556%0.557SS**Hα-helixtrans-85.8-38.8164-70.8-164.4159.900111.4R873 E874 D875 F879 K880 Q881R873-E877 PolarHBondContact O-N 3.23Å; E874-E877 PolarHBondContact O-N 2.86Å; D875-E877 VanDerWaalsContact C-N 3.33Å; E877-F879 VanDerWaalsContact C-N 3.35Å; E877-F879 PolarHBondContact O-N 3.4Å; E877-K880 PolarHBondContact O-N 2.65Å; E877-Q881 WeakPolarHBondContact O-CB 3.31Å; E877-Q881 PolarHBondContact O-N 2.96Å
878A36.5Very low36.8Very low52 Ų52116 Ų11643%0.4356%0.563SS.*Hα-helixtrans-58.4-44172.100000112.1E874 D875 K880 Q881 M882E874-A878 PolarHBondContact O-N 3.19Å; D875-A878 PolarHBondContact O-N 2.75Å; A878-K880 PolarHBondContact O-N 3.14Å; A878-Q881 WeakPolarHBondContact O-CB 3.43Å; A878-Q881 PolarHBondContact O-N 3.45Å; A878-Q881 VanDerWaalsContact O-N 3.11Å; A878-M882 PolarHBondContact O-N 2.96Å
879F33.4Very low36.6Very low153 Ų153117.4 Ų117.467%0.67157%0.568SS**Hα-helixtrans-63.9-39.1177.5-146-82.4000112.7D875 E877 Q881 M882 E883D875-F879 WeakPolarHBondContact O-CB 3.39Å; D875-F879 PolarHBondContact O-N 2.78Å; E877-F879 VanDerWaalsContact C-N 3.35Å; E877-F879 PolarHBondContact O-N 3.4Å; F879-Q881 VanDerWaalsContact C-N 3.27Å; F879-Q881 PolarHBondContact O-N 2.59Å; F879-M882 PolarHBondContact O-N 2.98Å; F879-E883 PolarHBondContact O-N 3.1Å; F879-E883 VanDerWaalsContact O-N 3.13Å
880K33.2Very low36.4Very low105 Ų105119.4 Ų119.446%0.45758%0.576SS.*Hα-helixtrans-71.7-20.7174.2-71.8170.8-169.7137.40113.4L876 E877 A878L876-K880 VanDerWaalsContact O-CD 3.25Å; L876-K880 WeakPolarHBondContact O-CD 3.26Å; L876-K880 WeakPolarHBondContact O-CE 3.21Å; L876-K880 VanDerWaalsContact O-CG 3.27Å; L876-K880 WeakPolarHBondContact O-CG 3.44Å; L876-K880 PolarHBondContact O-NZ 3.42Å; E877-K880 PolarHBondContact O-N 2.65Å; A878-K880 PolarHBondContact O-N 3.14Å
881Q32Very low35.9Very low93 Ų93123.8 Ų123.844%0.43559%0.588SS.*Hα-helixtrans-81.1-41174.3-168.457.536.500110.3E877 A878 F879 E883 K884 D885E877-Q881 WeakPolarHBondContact O-CB 3.31Å; E877-Q881 PolarHBondContact O-N 2.96Å; A878-Q881 WeakPolarHBondContact O-CB 3.43Å; A878-Q881 PolarHBondContact O-N 3.45Å; A878-Q881 VanDerWaalsContact O-N 3.11Å; F879-Q881 VanDerWaalsContact C-N 3.27Å; F879-Q881 PolarHBondContact O-N 2.59Å; Q881-E883 PolarHBondContact O-N 3.3Å; Q881-K884 WeakPolarHBondContact O-CB 3.25Å; Q881-K884 PolarHBondContact O-N 2.97Å; Q881-K884 VanDerWaalsContact O-N 3.12Å; Q881-D885 PolarHBondContact O-N 3.07Å
882M33.2Very low35.4Very low123 Ų123126.5 Ų126.561%0.60660%0.598SS**Hα-helixtrans-56.8-46.2170.2-73177.858.300112.3A878 F879 K884 D885 E886A878-M882 PolarHBondContact O-N 2.96Å; F879-M882 PolarHBondContact O-N 2.98Å; M882-K884 PolarHBondContact O-N 2.69Å; M882-K884 VanDerWaalsContact O-N 3.08Å; M882-D885 PolarHBondContact O-N 3.11Å; M882-E886 PolarHBondContact O-N 3.14Å
883E29.8Very low34.9Very low96 Ų96123.2 Ų123.245%0.44959%0.593SS.*Hα-helixtrans-65.4-12.8179.7-165.9172.6-152.300113.8K765 F879 Q881K765-E883 WeakPolarHBondContact CE-OE1 3.18Å; K765-E883 IonicContact NZ-OE1 2.75Å; K765-E883 PolarHBondContact NZ-OE1 2.8Å; F879-E883 PolarHBondContact O-N 3.1Å; F879-E883 VanDerWaalsContact O-N 3.13Å; Q881-E883 PolarHBondContact O-N 3.3Å
884K28.8Very low34.4Very low137 Ų137121.6 Ų121.660%0.59660%0.596SS**Hα-helixtrans-90-26.1171.6-82.5173.2178.7162.70114.4Q881 M882Q881-K884 WeakPolarHBondContact O-CB 3.25Å; Q881-K884 PolarHBondContact O-N 2.97Å; Q881-K884 VanDerWaalsContact O-N 3.12Å; M882-K884 PolarHBondContact O-N 2.69Å; M882-K884 VanDerWaalsContact O-N 3.08Å
885D31.9Very low33.8Very low124 Ų124119.5 Ų119.566%0.66359%0.589SS**Hα-helixtrans-91.7-3.8-175-66.1-29.2000112Q881 M882Q881-D885 PolarHBondContact O-N 3.07Å; M882-D885 PolarHBondContact O-N 3.11Å
886E31.7Very low33.1Very low173 Ų173120.2 Ų120.281%0.80859%0.588SS**THydrogen-bonded Turntrans-99.410.9171-65.1-163.9141.900114.8M882M882-E886 PolarHBondContact O-N 3.14Å
887L25.8Very low32.5Very low167 Ų167123.8 Ų123.887%0.87460%0.603SS**  trans-120.60-178.3-86.5170.5000114

Retrieved 887 of 887 residues in 659.1 ms (Link to these results)