A0A087YIG9_POEFO Loading...

Hepatic sodium/bile acid cotransporter

As a major transporter of conjugated bile salts from plasma into the hepatocyte, it plays a key role in the enterohepatic circulation of bile salts necessary for the solubilization and absorption of dietary fat and fat-soluble vitamins. It is strictly dependent on the extracellular presence of sodium. It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate. Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation.

AlphaFold DB , UniProt , Accession A0A087YIG9, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 350 aa.

Structure Viewer

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.5	Very low	33.7	Very low	254 Å²	254	146.4 Å²	146.4	100%	1.251	86%	0.864	S	S	*	*				0	108.4	0	-69.8	169.1	169.3	0	0	105.5
2	G	31	Very low	33.6	Very low	80 Å²	80	147.2 Å²	147.2	83%	0.825	86%	0.861	S	S	*	*			cis	134.3	105.8	23.9	0	0	0	0	0	108.3
3	G	30.1	Very low	33.3	Very low	74 Å²	74	151.5 Å²	151.5	76%	0.763	86%	0.864	S	S	*	*			trans	71.9	146.4	158.6	0	0	0	0	0	116.9
4	T	33.2	Very low	33.1	Very low	135 Å²	135	153.1 Å²	153.1	83%	0.828	87%	0.867	S	S	*	*			cis	-168.3	133.4	28.6	43.2	0	0	0	0	109.7
5	E	33.3	Very low	32.6	Very low	199 Å²	199	155.2 Å²	155.2	93%	0.93	86%	0.863	S	S	*	*			trans	-146.1	134.3	154.3	-73.4	-163.8	145.9	0	0	111.5
6	N	33.9	Very low	32.2	Very low	162 Å²	162	153.3 Å²	153.3	87%	0.866	85%	0.85	S	S	*	*			trans	-74.9	131.9	-175.3	-80.2	-41.8	0	0	0	112.2	F8	N6-F8 PolarHBondContact O-N 3.39Å
7	P	34.5	Very low	31.9	Very low	120 Å²	120	151.5 Å²	151.5	78%	0.779	84%	0.839	S	S	*	*			trans	-97.8	79.5	170.8	35.4	-27.3	0	0	0	110.3
8	F	36.8	Very low	31.7	Very low	201 Å²	201	151.1 Å²	151.1	88%	0.882	84%	0.835	S	S	*	*			trans	-136.5	72	159	-93.8	-77.1	0	0	0	108	N6	N6-F8 PolarHBondContact O-N 3.39Å
9	S	34.3	Very low	31.4	Very low	115 Å²	115	153.5 Å²	153.5	80%	0.804	84%	0.837	S	S	*	*			trans	-171.8	80.7	167.4	-71.9	0	0	0	0	109
10	D	33.2	Very low	31.3	Very low	156 Å²	156	151.3 Å²	151.3	83%	0.834	83%	0.833	S	S	*	*			trans	-163.4	131.7	134.5	-111.9	-24.5	0	0	0	112.2
11	P	36.1	Very low	31.7	Very low	114 Å²	114	149.1 Å²	149.1	74%	0.74	83%	0.826	S	S	*	*			trans	-106.6	71.6	-168.1	39.3	-27.7	0	0	0	111.7
12	D	32.8	Very low	31.1	Very low	156 Å²	156	144 Å²	144	83%	0.834	80%	0.804	S	S	*	*			trans	-143.7	24.7	-177.8	-98.3	-25.9	0	0	0	115.2
13	F	29.1	Very low	31.1	Very low	204 Å²	204	147.3 Å²	147.3	90%	0.895	80%	0.802	S	S	*	*	S	Bend	trans	-106	11.9	-174	-124.6	-87.2	0	0	0	116.7
14	L	30.9	Very low	31.2	Very low	173 Å²	173	149.5 Å²	149.5	91%	0.906	80%	0.801	S	S	*	*			trans	-143.1	76.8	178.8	-79	172	0	0	0	112.6
15	K	25.6	Very low	31.2	Very low	185 Å²	185	148 Å²	148	80%	0.804	80%	0.802	S	S	*	*			trans	-160.7	126.5	148	-116.8	-179.9	174	170.3	0	111.6
16	N	26.1	Very low	31.2	Very low	124 Å²	124	142 Å²	142	66%	0.663	78%	0.779	S	S	*	*			trans	77.3	132.1	148.6	-67	11.7	0	0	0	117.2
17	D	27.9	Very low	31.1	Very low	124 Å²	124	140.9 Å²	140.9	66%	0.663	77%	0.773	S	S	*	*			cis	-159.9	154	9.2	-85.2	-35.5	0	0	0	110.6
18	D	26.9	Very low	31	Very low	143 Å²	143	142 Å²	142	77%	0.765	78%	0.778	S	S	*	*			trans	45.2	115.8	143.6	-70.4	-25.2	0	0	0	122.5
19	F	25.8	Very low	30.8	Very low	197 Å²	197	136.7 Å²	136.7	86%	0.864	77%	0.765	S	S	*	*				-177.5	117.5	107.2	-124.9	-106.5	0	0	0	111
20	S	29.3	Very low	30.9	Very low	109 Å²	109	138 Å²	138	76%	0.762	76%	0.763	S	S	*	*			trans	-86.1	147.6	152.3	-68.1	0	0	0	0	107.4
21	P	40.9	Very low	31.1	Very low	107 Å²	107	138 Å²	138	70%	0.695	76%	0.762	S	S	*	*				-150.1	-178	56.4	36.5	-13.7	0	0	0	116.1
22	N	22.4	Very low	31	Very low	147 Å²	147	142.7 Å²	142.7	79%	0.786	77%	0.766	S	S	*	*			trans	92.5	107.4	164	-81.9	-18.7	0	0	0	120.1
23	L	31.1	Very low	31.3	Very low	149 Å²	149	140.2 Å²	140.2	78%	0.78	76%	0.759	S	S	*	*				64	97.7	119.7	-158	79.9	0	0	0	116.8
24	T	30.6	Very low	32.3	Very low	119 Å²	119	136 Å²	136	73%	0.73	75%	0.754	S	S	*	*				-161.9	116.3	118.2	-0.4	0	0	0	0	111.8	T26	T24-T26 WeakPolarHBondContact CB-OG1 3.5Å; T24-T26 WeakPolarHBondContact CG2-OG1 3.33Å; T24-T26 PolarHBondContact O-N 3.23Å
25	A	34.8	Very low	33.1	Very low	103 Å²	103	135.1 Å²	135.1	85%	0.851	75%	0.75	S	S	*	*			trans	-69.8	48.7	171.4	0	0	0	0	0	112.2
26	T	31.5	Very low	34.4	Very low	75 Å²	75	129.7 Å²	129.7	46%	0.46	73%	0.73	S	S	.	*			trans	-110.7	-11.3	-163.6	-44	0	0	0	0	114.1	T24 S29	T24-T26 WeakPolarHBondContact CB-OG1 3.5Å; T24-T26 WeakPolarHBondContact CG2-OG1 3.33Å; T24-T26 PolarHBondContact O-N 3.23Å; T26-S29 PolarHBondContact O-OG 2.95Å
27	N	32.8	Very low	36.4	Very low	138 Å²	138	126.7 Å²	126.7	74%	0.738	72%	0.718	S	S	*	*	S	Bend	trans	-113.2	5.3	-169	-67.1	-9.7	0	0	0	115.7
28	T	33.1	Very low	38.4	Very low	144 Å²	144	126 Å²	126	88%	0.883	72%	0.72	S	S	*	*	S	Bend	trans	-101	1.1	173.4	-8.5	0	0	0	0	113.7
29	S	32.5	Very low	40.5	Very low	88 Å²	88	124.1 Å²	124.1	62%	0.615	71%	0.714	S	S	*	*			trans	-89.1	12	-179.7	48.6	0	0	0	0	114.6	T26	T26-S29 PolarHBondContact O-OG 2.95Å
30	L	36.6	Very low	42.4	Very low	142 Å²	142	119.2 Å²	119.2	74%	0.743	70%	0.695	S	S	*	*	S	Bend	trans	-99.7	11.4	-168.3	-89	160.9	0	0	0	116.3
31	L	35.4	Very low	44.3	Very low	158 Å²	158	117.8 Å²	117.8	83%	0.827	68%	0.678	S	S	*	*	S	Bend	trans	-120.8	2.7	177	-94.3	157.5	0	0	0	116.3
32	Y	34.5	Very low	45.9	Very low	211 Å²	211	119.6 Å²	119.6	83%	0.827	68%	0.675	S	S	*	*	S	Bend	trans	-141.9	102.5	161.3	-80.3	-88.5	0	0	0	108.4	S34	Y32-S34 PolarHBondContact O-N 3.08Å; Y32-S34 VanDerWaalsContact O-N 3.12Å
33	P	40.4	Very low	48.5	Very low	105 Å²	105	115.7 Å²	115.7	68%	0.682	66%	0.657	S	S	*	*			trans	-61.7	122	170.1	25.5	-28.7	0	0	0	107.3	L35	P33-L35 VanDerWaalsContact C-N 3.27Å; P33-L35 PolarHBondContact O-N 3.25Å
34	S	48.5	Very low	50.4	Low	114 Å²	114	112.1 Å²	112.1	80%	0.797	64%	0.638	S	S	*	*			trans	-54.2	90.2	168	50.5	0	0	0	0	109.4	Y32 L36	Y32-S34 PolarHBondContact O-N 3.08Å; Y32-S34 VanDerWaalsContact O-N 3.12Å; S34-L36 PolarHBondContact O-N 3.01Å
35	L	48.2	Very low	52.4	Low	156 Å²	156	111.1 Å²	111.1	82%	0.817	63%	0.628	S	S	*	*			trans	-78	-1	-179.3	-137	85.3	0	0	0	112.6	P33	P33-L35 VanDerWaalsContact C-N 3.27Å; P33-L35 PolarHBondContact O-N 3.25Å
36	L	52.4	Low	54.5	Low	71 Å²	71	110.8 Å²	110.8	37%	0.372	61%	0.611	S	S	.	*	S	Bend	trans	-105.5	121.8	-179.3	-106.1	58.7	0	0	0	110	S34 M40 D41 I44	S34-L36 PolarHBondContact O-N 3.01Å; L36-M40 HydrophobicContact CB-CB 4.25Å; L36-M40 HydrophobicContact CD1-CG 4.09Å; L36-M40 HydrophobicContact CD2-CB 4.3Å; L36-M40 HydrophobicContact CD2-CG 3.93Å; L36-M40 HydrophobicContact CG-CB 3.75Å; L36-M40 HydrophobicContact CG-CG 3.51Å; L36-D41 WeakPolarHBondContact CD2-OD1 3.3Å; L36-I44 HydrophobicContact CD2-CD1 3.32Å; L36-I44 HydrophobicContact CG-CD1 4.47Å
37	S	69.4	Low	56.6	Low	60 Å²	60	111.7 Å²	111.7	42%	0.42	61%	0.612	S	S	.	*			trans	-60	151	167.5	72.5	0	0	0	0	109.3	V39 M40 D41	S37-V39 PolarHBondContact O-N 3.15Å; S37-M40 WeakPolarHBondContact O-CA 3.32Å; S37-M40 WeakPolarHBondContact O-CB 3.29Å; S37-M40 PolarHBondContact O-N 3.16Å; S37-M40 PolarHBondContact OG-N 3.48Å; S37-D41 PolarHBondContact O-N 3.11Å; S37-D41 VanDerWaalsContact O-N 3.14Å
38	P	70	Confident	58.5	Low	110 Å²	110	109.2 Å²	109.2	71%	0.714	60%	0.597	S	S	*	*	H	α-helix	trans	-56	-21.1	176	18.9	-31	0	0	0	113.2	K42	P38-K42 WeakPolarHBondContact O-CB 3.2Å; P38-K42 PolarHBondContact O-N 3.26Å
39	V	70.1	Confident	60.5	Low	103 Å²	103	106.9 Å²	106.9	62%	0.624	58%	0.578	S	S	*	*	H	α-helix	trans	-71.9	-40.4	172.2	-177.6	0	0	0	0	111.6	S37 K42 T43	S37-V39 PolarHBondContact O-N 3.15Å; V39-K42 PolarHBondContact O-N 3.36Å; V39-T43 WeakPolarHBondContact O-CB 3.31Å; V39-T43 PolarHBondContact O-N 3.39Å; V39-T43 PolarHBondContact O-OG1 3.33Å
40	M	66.6	Low	62.8	Low	95 Å²	95	106 Å²	106	47%	0.468	57%	0.569	S	S	.	*	H	α-helix	trans	-68.8	-41.1	178.1	-164.1	72.4	71.8	0	0	111.3	L36 S37 K42 T43 I44	L36-M40 HydrophobicContact CB-CB 4.25Å; L36-M40 HydrophobicContact CD1-CG 4.09Å; L36-M40 HydrophobicContact CD2-CB 4.3Å; L36-M40 HydrophobicContact CD2-CG 3.93Å; L36-M40 HydrophobicContact CG-CB 3.75Å; L36-M40 HydrophobicContact CG-CG 3.51Å; S37-M40 WeakPolarHBondContact O-CA 3.32Å; S37-M40 WeakPolarHBondContact O-CB 3.29Å; S37-M40 PolarHBondContact O-N 3.16Å; S37-M40 PolarHBondContact OG-N 3.48Å; M40-K42 PolarHBondContact O-N 3.33Å; M40-T43 PolarHBondContact O-N 3.22Å; M40-I44 HydrophobicContact CG-CD1 4.35Å; M40-I44 WeakPolarHBondContact O-CG1 3.43Å; M40-I44 PolarHBondContact O-N 2.83Å
41	D	68.6	Low	64.7	Low	78 Å²	78	101 Å²	101	42%	0.417	55%	0.545	S	S	.	.	H	α-helix	trans	-61.5	-43.1	173.6	-84.7	-18.9	0	0	0	112.3	L36 S37 T43 I44 N45	L36-D41 WeakPolarHBondContact CD2-OD1 3.3Å; S37-D41 PolarHBondContact O-N 3.11Å; S37-D41 VanDerWaalsContact O-N 3.14Å; D41-T43 VanDerWaalsContact C-N 3.32Å; D41-T43 PolarHBondContact O-N 2.94Å; D41-I44 PolarHBondContact O-N 3.02Å; D41-N45 WeakPolarHBondContact O-CB 3.43Å; D41-N45 PolarHBondContact O-N 2.61Å; D41-N45 PolarHBondContact O-ND2 3.46Å
42	K	74.4	Confident	66.4	Low	145 Å²	145	95.4 Å²	95.4	63%	0.63	52%	0.515	S	S	*	.	H	α-helix	trans	-64.1	-40.1	176	-168.1	173.3	-176.7	177.6	0	111.6	P38 V39 M40 N45 I46	P38-K42 WeakPolarHBondContact O-CB 3.2Å; P38-K42 PolarHBondContact O-N 3.26Å; V39-K42 PolarHBondContact O-N 3.36Å; M40-K42 PolarHBondContact O-N 3.33Å; K42-N45 PolarHBondContact O-N 2.99Å; K42-I46 HydrophobicContact CG-CD1 4.21Å; K42-I46 VanDerWaalsContact O-CG1 3.3Å; K42-I46 WeakPolarHBondContact O-CG1 3.27Å; K42-I46 PolarHBondContact O-N 3.29Å
43	T	76.5	Confident	68.6	Low	65 Å²	65	89.4 Å²	89.4	40%	0.399	50%	0.497	S	S	.	.	H	α-helix	trans	-65.1	-44.9	178.5	-57.3	0	0	0	0	111.2	V39 M40 D41 N45 I46 I47	V39-T43 WeakPolarHBondContact O-CB 3.31Å; V39-T43 PolarHBondContact O-N 3.39Å; V39-T43 PolarHBondContact O-OG1 3.33Å; M40-T43 PolarHBondContact O-N 3.22Å; D41-T43 VanDerWaalsContact C-N 3.32Å; D41-T43 PolarHBondContact O-N 2.94Å; T43-N45 PolarHBondContact O-N 2.8Å; T43-I46 PolarHBondContact O-N 2.68Å; T43-I47 HydrophobicContact CG2-CD1 3.94Å; T43-I47 VanDerWaalsContact O-CG1 3.29Å; T43-I47 WeakPolarHBondContact O-CG1 3.23Å; T43-I47 PolarHBondContact O-N 2.94Å
44	I	72.5	Confident	70.5	Confident	74 Å²	74	87.6 Å²	87.6	38%	0.379	48%	0.481	S	S	.	.	H	α-helix	trans	-61.6	-45.1	176.2	-71.3	172.9	0	0	0	111	L36 M40 D41 I46 I47 M48	L36-I44 HydrophobicContact CD2-CD1 3.32Å; L36-I44 HydrophobicContact CG-CD1 4.47Å; M40-I44 HydrophobicContact CG-CD1 4.35Å; M40-I44 WeakPolarHBondContact O-CG1 3.43Å; M40-I44 PolarHBondContact O-N 2.83Å; D41-I44 PolarHBondContact O-N 3.02Å; I44-I46 VanDerWaalsContact C-N 3.35Å; I44-I46 PolarHBondContact O-N 2.82Å; I44-I47 PolarHBondContact O-N 3.33Å; I44-M48 HydrophobicContact CG2-CG 4.2Å; I44-M48 WeakPolarHBondContact O-CB 3.24Å; I44-M48 WeakPolarHBondContact O-CG 3.42Å; I44-M48 PolarHBondContact O-N 2.86Å
45	N	71.5	Confident	71.8	Confident	98 Å²	98	82.5 Å²	82.5	52%	0.524	45%	0.445	S	S	.	.	H	α-helix	trans	-60.7	-42.4	177.8	-79.2	-52.8	0	0	0	112.4	D41 K42 T43 M48 I49	D41-N45 WeakPolarHBondContact O-CB 3.43Å; D41-N45 PolarHBondContact O-N 2.61Å; D41-N45 PolarHBondContact O-ND2 3.46Å; K42-N45 PolarHBondContact O-N 2.99Å; T43-N45 PolarHBondContact O-N 2.8Å; N45-M48 PolarHBondContact O-N 3.02Å; N45-I49 VanDerWaalsContact O-CG1 3.29Å; N45-I49 WeakPolarHBondContact O-CG1 3.39Å; N45-I49 PolarHBondContact O-N 3.47Å
46	I	78.8	Confident	73.1	Confident	97 Å²	97	75 Å²	75	50%	0.497	41%	0.406	S	S	.	.	H	α-helix	trans	-63.7	-43.1	176.5	-68.5	166.2	0	0	0	111.2	K42 T43 I44 I49 T50	K42-I46 HydrophobicContact CG-CD1 4.21Å; K42-I46 VanDerWaalsContact O-CG1 3.3Å; K42-I46 WeakPolarHBondContact O-CG1 3.27Å; K42-I46 PolarHBondContact O-N 3.29Å; T43-I46 PolarHBondContact O-N 2.68Å; I44-I46 VanDerWaalsContact C-N 3.35Å; I44-I46 PolarHBondContact O-N 2.82Å; I46-I49 PolarHBondContact O-N 3.12Å; I46-T50 WeakPolarHBondContact O-CB 3.45Å; I46-T50 PolarHBondContact O-N 2.78Å; I46-T50 PolarHBondContact O-OG1 2.86Å
47	I	76.9	Confident	74.5	Confident	93 Å²	93	73 Å²	73	48%	0.477	40%	0.397	S	S	.	.	H	α-helix	trans	-61.3	-46.3	176.9	-69.5	167.4	0	0	0	110.2	T43 I44 I49 T50 V51	T43-I47 HydrophobicContact CG2-CD1 3.94Å; T43-I47 VanDerWaalsContact O-CG1 3.29Å; T43-I47 WeakPolarHBondContact O-CG1 3.23Å; T43-I47 PolarHBondContact O-N 2.94Å; I44-I47 PolarHBondContact O-N 3.33Å; I47-I49 PolarHBondContact O-N 3.26Å; I47-T50 PolarHBondContact O-N 3.08Å; I47-V51 HydrophobicContact CG2-CG2 4.32Å; I47-V51 WeakPolarHBondContact O-CB 3.37Å; I47-V51 WeakPolarHBondContact O-CG2 3.34Å; I47-V51 PolarHBondContact O-N 3.08Å
48	M	71	Confident	75.1	Confident	86 Å²	86	70.3 Å²	70.3	42%	0.424	38%	0.378	S	S	.	.	H	α-helix	trans	-62.5	-43.8	-179.7	-69.3	-67	-93.3	0	0	111.9	I44 N45 T50 V51 L52 P291	I44-M48 HydrophobicContact CG2-CG 4.2Å; I44-M48 WeakPolarHBondContact O-CB 3.24Å; I44-M48 WeakPolarHBondContact O-CG 3.42Å; I44-M48 PolarHBondContact O-N 2.86Å; N45-M48 PolarHBondContact O-N 3.02Å; M48-T50 VanDerWaalsContact C-N 3.33Å; M48-T50 PolarHBondContact O-N 3.16Å; M48-V51 PolarHBondContact O-N 3.16Å; M48-L52 WeakPolarHBondContact O-CB 3.36Å; M48-L52 PolarHBondContact O-N 2.96Å; M48-P291 HydrophobicContact CE-CG 3.77Å
49	I	76.8	Confident	75.3	Confident	96 Å²	96	65.6 Å²	65.6	49%	0.492	35%	0.346	S	S	.	.	H	α-helix	trans	-64	-38.9	175.9	-67.3	166.3	0	0	0	111.2	N45 I46 I47 L52 L53	N45-I49 VanDerWaalsContact O-CG1 3.29Å; N45-I49 WeakPolarHBondContact O-CG1 3.39Å; N45-I49 PolarHBondContact O-N 3.47Å; I46-I49 PolarHBondContact O-N 3.12Å; I47-I49 PolarHBondContact O-N 3.26Å; I49-L52 VanDerWaalsContact O-CB 3.31Å; I49-L52 WeakPolarHBondContact O-CB 3.28Å; I49-L52 PolarHBondContact O-N 2.82Å; I49-L53 HydrophobicContact CG2-CD1 4.46Å; I49-L53 WeakPolarHBondContact O-CG 3.28Å; I49-L53 PolarHBondContact O-N 2.89Å
50	T	79.8	Confident	75.5	Confident	69 Å²	69	60.7 Å²	60.7	42%	0.423	32%	0.317	S	S	.	.	H	α-helix	trans	-68.6	-45.7	179.4	-55.2	0	0	0	0	111.4	I46 I47 M48 L52 L53 I54	I46-T50 WeakPolarHBondContact O-CB 3.45Å; I46-T50 PolarHBondContact O-N 2.78Å; I46-T50 PolarHBondContact O-OG1 2.86Å; I47-T50 PolarHBondContact O-N 3.08Å; M48-T50 VanDerWaalsContact C-N 3.33Å; M48-T50 PolarHBondContact O-N 3.16Å; T50-L52 VanDerWaalsContact C-N 3.29Å; T50-L52 PolarHBondContact O-N 2.9Å; T50-L53 PolarHBondContact O-N 3.03Å; T50-I54 HydrophobicContact CG2-CD1 4.15Å; T50-I54 WeakPolarHBondContact O-CG1 3.34Å; T50-I54 PolarHBondContact O-N 3Å
51	V	75.8	Confident	76.1	Confident	38 Å²	38	56.3 Å²	56.3	23%	0.23	30%	0.295	C	S	.	.	H	α-helix	trans	-59	-44.3	174.5	166.9	0	0	0	0	110.4	I47 M48 L53 I54 V55 V209	I47-V51 HydrophobicContact CG2-CG2 4.32Å; I47-V51 WeakPolarHBondContact O-CB 3.37Å; I47-V51 WeakPolarHBondContact O-CG2 3.34Å; I47-V51 PolarHBondContact O-N 3.08Å; M48-V51 PolarHBondContact O-N 3.16Å; V51-L53 PolarHBondContact O-N 2.95Å; V51-I54 PolarHBondContact O-N 3.34Å; V51-V55 HydrophobicContact CG1-CG2 4.23Å; V51-V55 WeakPolarHBondContact O-CB 3.39Å; V51-V55 VanDerWaalsContact O-CG2 3.24Å; V51-V55 WeakPolarHBondContact O-CG2 3.36Å; V51-V55 PolarHBondContact O-N 3.43Å; V51-V209 HydrophobicContact CB-CG1 4.5Å; V51-V209 HydrophobicContact CG1-CG1 3.76Å; V51-V209 HydrophobicContact CG2-CG1 4.28Å
52	L	72.4	Confident	76.2	Confident	40 Å²	40	55 Å²	55	21%	0.209	29%	0.29	C	S	.	.	H	α-helix	trans	-52.7	-53.9	173.6	158.8	60	0	0	0	112	M48 I49 T50 I54 V55 M56 V287	M48-L52 WeakPolarHBondContact O-CB 3.36Å; M48-L52 PolarHBondContact O-N 2.96Å; I49-L52 VanDerWaalsContact O-CB 3.31Å; I49-L52 WeakPolarHBondContact O-CB 3.28Å; I49-L52 PolarHBondContact O-N 2.82Å; T50-L52 VanDerWaalsContact C-N 3.29Å; T50-L52 PolarHBondContact O-N 2.9Å; L52-I54 PolarHBondContact O-N 2.89Å; L52-V55 PolarHBondContact O-N 3.47Å; L52-M56 HydrophobicContact CD1-CG 3.83Å; L52-M56 WeakPolarHBondContact O-CG 3.49Å; L52-M56 PolarHBondContact O-N 3.17Å; L52-V287 HydrophobicContact CB-CG2 4.45Å; L52-V287 HydrophobicContact CD1-CB 3.68Å; L52-V287 HydrophobicContact CD1-CG1 3.01Å; L52-V287 HydrophobicContact CD1-CG2 3.33Å; L52-V287 HydrophobicContact CD2-CG1 4.4Å; L52-V287 HydrophobicContact CG-CG1 4.29Å; L52-V287 HydrophobicContact CG-CG2 4.49Å
53	L	79.5	Confident	75.8	Confident	85 Å²	85	48.6 Å²	48.6	45%	0.445	26%	0.262	S	S	.	.	H	α-helix	trans	-60.4	-45.4	-179.3	-71.7	174.4	0	0	0	111.8	I49 T50 V51 V55 M56 V57 P184	I49-L53 HydrophobicContact CG2-CD1 4.46Å; I49-L53 WeakPolarHBondContact O-CG 3.28Å; I49-L53 PolarHBondContact O-N 2.89Å; T50-L53 PolarHBondContact O-N 3.03Å; V51-L53 PolarHBondContact O-N 2.95Å; L53-V55 PolarHBondContact O-N 3.3Å; L53-M56 PolarHBondContact O-N 3.15Å; L53-V57 VanDerWaalsContact O-CG2 3.29Å; L53-V57 WeakPolarHBondContact O-CG2 3.38Å; L53-V57 PolarHBondContact O-N 3.25Å; L53-P184 HydrophobicContact CD2-CB 3.9Å; L53-P184 HydrophobicContact CD2-CG 4.02Å
54	I	80.9	Confident	75.4	Confident	66 Å²	66	49.8 Å²	49.8	34%	0.338	26%	0.264	S	S	.	.	H	α-helix	trans	-60.5	-46.9	178.7	-67.4	168.1	0	0	0	110.7	T50 V51 L52 M56 S58	T50-I54 HydrophobicContact CG2-CD1 4.15Å; T50-I54 WeakPolarHBondContact O-CG1 3.34Å; T50-I54 PolarHBondContact O-N 3Å; V51-I54 PolarHBondContact O-N 3.34Å; L52-I54 PolarHBondContact O-N 2.89Å; I54-M56 VanDerWaalsContact C-N 3.34Å; I54-M56 PolarHBondContact O-N 3.39Å; I54-S58 WeakPolarHBondContact O-CB 3.3Å; I54-S58 PolarHBondContact O-N 3.4Å
55	V	75.5	Confident	74.9	Confident	7 Å²	7	47.9 Å²	47.9	4%	0.042	26%	0.255	C	S	.	.	H	α-helix	trans	-64.7	-39.1	-179.3	170.7	0	0	0	0	111	V51 L52 L53 S58 L59 V209 L210 T283	V51-V55 HydrophobicContact CG1-CG2 4.23Å; V51-V55 WeakPolarHBondContact O-CB 3.39Å; V51-V55 VanDerWaalsContact O-CG2 3.24Å; V51-V55 WeakPolarHBondContact O-CG2 3.36Å; V51-V55 PolarHBondContact O-N 3.43Å; L52-V55 PolarHBondContact O-N 3.47Å; L53-V55 PolarHBondContact O-N 3.3Å; V55-S58 WeakPolarHBondContact O-CB 3.41Å; V55-S58 PolarHBondContact O-N 3.31Å; V55-L59 WeakPolarHBondContact O-CB 3.24Å; V55-L59 PolarHBondContact O-N 2.98Å; V55-V209 HydrophobicContact CG2-CG1 4.23Å; V55-L210 HydrophobicContact CG1-CD1 4.37Å; V55-L210 HydrophobicContact CG2-CB 4.46Å; V55-T283 HydrophobicContact CG1-CG2 3.34Å
56	M	75.8	Confident	74.4	Confident	0 Å²	0	47.6 Å²	47.6	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-73.3	-39.2	179.4	-71.3	-57.2	171.3	0	0	113.4	L52 L53 I54 S58 L59 G60 I181 P184 C185 T283 V284 V287	L52-M56 HydrophobicContact CD1-CG 3.83Å; L52-M56 WeakPolarHBondContact O-CG 3.49Å; L52-M56 PolarHBondContact O-N 3.17Å; L53-M56 PolarHBondContact O-N 3.15Å; I54-M56 VanDerWaalsContact C-N 3.34Å; I54-M56 PolarHBondContact O-N 3.39Å; M56-S58 VanDerWaalsContact C-N 3.33Å; M56-L59 WeakPolarHBondContact O-CB 3.36Å; M56-L59 PolarHBondContact O-N 2.97Å; M56-L59 HydrophobicContact SD-CD2 3.8Å; M56-G60 PolarHBondContact O-N 3.19Å; M56-I181 HydrophobicContact CE-CB 4.46Å; M56-I181 HydrophobicContact CE-CD1 4.48Å; M56-I181 HydrophobicContact CE-CG1 4.1Å; M56-I181 HydrophobicContact CE-CG2 3.69Å; M56-I181 HydrophobicContact CG-CG2 4.41Å; M56-I181 HydrophobicContact SD-CG2 3.65Å; M56-P184 HydrophobicContact CB-CB 3.82Å; M56-P184 HydrophobicContact CB-CG 3.65Å; M56-P184 HydrophobicContact CG-CG 4.31Å; M56-C185 WeakPolarHBondContact O-CA 3.45Å; M56-T283 HydrophobicContact CE-CG2 3.44Å; M56-T283 VanDerWaalsContact CE-CG2 3.44Å; M56-T283 HydrophobicContact SD-CG2 3.89Å; M56-V284 HydrophobicContact CE-CG2 4.35Å; M56-V287 HydrophobicContact CE-CB 3.64Å; M56-V287 HydrophobicContact CE-CG1 3.52Å; M56-V287 HydrophobicContact CE-CG2 3.71Å
57	V	81.9	Confident	73.7	Confident	29 Å²	29	46.5 Å²	46.5	18%	0.176	25%	0.249	C	C	.	.	H	α-helix	trans	-64.3	-42.2	171.3	177.6	0	0	0	0	110.3	L53 L59 G60 C61 P184 G188 I191 I202	L53-V57 VanDerWaalsContact O-CG2 3.29Å; L53-V57 WeakPolarHBondContact O-CG2 3.38Å; L53-V57 PolarHBondContact O-N 3.25Å; V57-L59 VanDerWaalsContact C-N 3.32Å; V57-L59 PolarHBondContact O-N 2.99Å; V57-G60 PolarHBondContact O-N 3.34Å; V57-C61 WeakPolarHBondContact O-CB 3.36Å; V57-C61 PolarHBondContact O-N 3.41Å; V57-C61 PolarHBondContact O-SG 3.5Å; V57-P184 WeakPolarHBondContact CA-O 3.34Å; V57-P184 HydrophobicContact CG2-CB 3.98Å; V57-P184 WeakPolarHBondContact CG2-O 3.19Å; V57-G188 WeakPolarHBondContact O-CA 3.35Å; V57-I191 HydrophobicContact CG1-CD1 3.88Å; V57-I202 HydrophobicContact CG1-CG2 4.05Å
58	S	80.9	Confident	72.9	Confident	3 Å²	3	42.9 Å²	42.9	2%	0.021	23%	0.23	C	C	.	.	H	α-helix	trans	-59.1	-42.1	174.6	171.7	0	0	0	0	112.4	I54 V55 M56 C61 T62 I202 T203 G206	I54-S58 WeakPolarHBondContact O-CB 3.3Å; I54-S58 PolarHBondContact O-N 3.4Å; V55-S58 WeakPolarHBondContact O-CB 3.41Å; V55-S58 PolarHBondContact O-N 3.31Å; M56-S58 VanDerWaalsContact C-N 3.33Å; S58-C61 WeakPolarHBondContact O-CB 3.21Å; S58-C61 PolarHBondContact O-N 3.1Å; S58-T62 WeakPolarHBondContact O-CG2 3.49Å; S58-T62 PolarHBondContact O-N 2.9Å; S58-I202 PolarHBondContact OG-O 3.18Å; S58-T203 WeakPolarHBondContact OG-CA 3.4Å; S58-T203 PolarHBondContact OG-O 2.82Å; S58-G206 WeakPolarHBondContact OG-CA 3.14Å
59	L	75.1	Confident	72.5	Confident	11 Å²	11	47 Å²	47	6%	0.058	25%	0.246	C	C	.	.	H	α-helix	trans	-62.9	-49.2	176.3	175.2	74	0	0	0	110.9	V55 M56 V57 C61 T62 L280 T283	V55-L59 WeakPolarHBondContact O-CB 3.24Å; V55-L59 PolarHBondContact O-N 2.98Å; M56-L59 WeakPolarHBondContact O-CB 3.36Å; M56-L59 PolarHBondContact O-N 2.97Å; M56-L59 HydrophobicContact SD-CD2 3.8Å; V57-L59 VanDerWaalsContact C-N 3.32Å; V57-L59 PolarHBondContact O-N 2.99Å; L59-C61 PolarHBondContact O-N 3.2Å; L59-T62 WeakPolarHBondContact O-CB 3.37Å; L59-T62 PolarHBondContact O-N 3.43Å; L59-T62 PolarHBondContact O-OG1 3.37Å; L59-L280 HydrophobicContact CD1-CB 4.11Å; L59-L280 HydrophobicContact CD1-CD1 3.41Å; L59-L280 VanDerWaalsContact CD1-CD1 3.41Å; L59-L280 HydrophobicContact CD1-CG 4.35Å; L59-L280 HydrophobicContact CD2-CD1 3.11Å; L59-L280 HydrophobicContact CG-CD1 3.73Å; L59-T283 HydrophobicContact CD2-CG2 4.25Å
60	G	75.3	Confident	71.5	Confident	0 Å²	0	48 Å²	48	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-58.1	-35.5	175.3	0	0	0	0	0	112.9	M56 V57 T62 M63 C185 I189	M56-G60 PolarHBondContact O-N 3.19Å; V57-G60 PolarHBondContact O-N 3.34Å; G60-T62 PolarHBondContact O-N 3.18Å; G60-M63 WeakPolarHBondContact O-CB 3.36Å; G60-M63 WeakPolarHBondContact O-CG 3.31Å; G60-M63 PolarHBondContact O-N 3.26Å; G60-M63 VanDerWaalsContact O-N 3.16Å; G60-C185 WeakPolarHBondContact CA-O 3.39Å; G60-I189 WeakPolarHBondContact O-CA 3.44Å; G60-I189 WeakPolarHBondContact O-CG1 3.47Å; G60-I189 PolarHBondContact O-N 3.44Å
61	C	77.6	Confident	70.4	Confident	2 Å²	2	47.7 Å²	47.7	1%	0.014	25%	0.246	C	C	.	.	H	α-helix	trans	-62.2	-26.7	176.2	-74.1	0	0	0	0	113.2	V57 S58 L59 M63 G188 N192 S199 T203	V57-C61 WeakPolarHBondContact O-CB 3.36Å; V57-C61 PolarHBondContact O-N 3.41Å; V57-C61 PolarHBondContact O-SG 3.5Å; S58-C61 WeakPolarHBondContact O-CB 3.21Å; S58-C61 PolarHBondContact O-N 3.1Å; L59-C61 PolarHBondContact O-N 3.2Å; C61-M63 PolarHBondContact O-N 2.72Å; C61-G188 PolarHBondContact SG-O 3.28Å; C61-N192 PolarHBondContact O-ND2 3.3Å; C61-N192 PolarHBondContact O-OD1 3.27Å; C61-S199 VanDerWaalsContact CB-OG 3.31Å; C61-S199 WeakPolarHBondContact CB-OG 3.41Å; C61-S199 PolarHBondContact O-OG 3.26Å; C61-T203 WeakPolarHBondContact CB-OG1 3.3Å
62	T	70.8	Confident	69.6	Low	51 Å²	51	51 Å²	51	31%	0.313	26%	0.261	S	S	.	.	T	Hydrogen-bonded Turn	trans	-73.3	-9.8	177.8	70.3	0	0	0	0	114.2	S58 L59 G60 E64 T203	S58-T62 WeakPolarHBondContact O-CG2 3.49Å; S58-T62 PolarHBondContact O-N 2.9Å; L59-T62 WeakPolarHBondContact O-CB 3.37Å; L59-T62 PolarHBondContact O-N 3.43Å; L59-T62 PolarHBondContact O-OG1 3.37Å; G60-T62 PolarHBondContact O-N 3.18Å; T62-E64 PolarHBondContact O-N 2.98Å; T62-T203 HydrophobicContact CG2-CG2 3.55Å
63	M	67.7	Low	68.7	Low	10 Å²	10	56 Å²	56	5%	0.049	29%	0.287	C	S	.	.			trans	-87.3	109.8	-170	-54.2	178.6	85	0	0	111.6	G60 C61 V65 T144 L145 L148 I189 N192	G60-M63 WeakPolarHBondContact O-CB 3.36Å; G60-M63 WeakPolarHBondContact O-CG 3.31Å; G60-M63 PolarHBondContact O-N 3.26Å; G60-M63 VanDerWaalsContact O-N 3.16Å; C61-M63 PolarHBondContact O-N 2.72Å; M63-V65 PolarHBondContact O-N 3.38Å; M63-T144 HydrophobicContact CB-CG2 4.2Å; M63-T144 HydrophobicContact CE-CG2 3.28Å; M63-T144 WeakPolarHBondContact CE-O 3.34Å; M63-T144 HydrophobicContact CG-CG2 3.64Å; M63-T144 HydrophobicContact SD-CG2 4.19Å; M63-L145 HydrophobicContact CE-CD2 4.22Å; M63-L148 HydrophobicContact CE-CD1 4.27Å; M63-L148 HydrophobicContact CE-CD2 4.07Å; M63-L148 HydrophobicContact CE-CG 3.98Å; M63-L148 HydrophobicContact SD-CD2 4.25Å; M63-I189 HydrophobicContact CB-CG1 4.15Å; M63-I189 HydrophobicContact CE-CD1 4Å; M63-I189 HydrophobicContact CG-CG1 4.19Å; M63-I189 HydrophobicContact SD-CD1 3.25Å; M63-I189 WeakPolarHBondContact SD-CD1 3.44Å; M63-I189 HydrophobicContact SD-CG1 3.34Å; M63-I189 WeakPolarHBondContact SD-CG1 3.28Å; M63-N192 PolarHBondContact O-ND2 3.32Å
64	E	67.2	Low	68	Low	91 Å²	91	58.2 Å²	58.2	43%	0.425	29%	0.293	S	S	.	.			trans	-80.5	81.1	-177.4	-67.4	-176.8	141.4	0	0	113	T62 T66 K67	T62-E64 PolarHBondContact O-N 2.98Å; E64-T66 VanDerWaalsContact C-N 3.28Å; E64-T66 PolarHBondContact O-N 3.18Å; E64-K67 HydrophobicContact CB-CD 4.42Å; E64-K67 HydrophobicContact CB-CG 4.43Å; E64-K67 VanDerWaalsContact CD-NZ 3.27Å; E64-K67 IonicContact OE1-NZ 3.15Å; E64-K67 PolarHBondContact OE1-NZ 2.9Å; E64-K67 VanDerWaalsContact OE1-NZ 3.15Å; E64-K67 VanDerWaalsContact OE2-CD 3.26Å; E64-K67 WeakPolarHBondContact OE2-CD 3.35Å; E64-K67 WeakPolarHBondContact OE2-CE 3.5Å; E64-K67 IonicContact OE2-NZ 2.66Å; E64-K67 PolarHBondContact OE2-NZ 3.2Å
65	V	62.2	Low	67.6	Low	34 Å²	34	59.4 Å²	59.4	21%	0.206	31%	0.305	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64	-31.1	-179.6	-170.2	0	0	0	0	113	M63 K67 I68 L145 I189 Y193	M63-V65 PolarHBondContact O-N 3.38Å; V65-K67 VanDerWaalsContact C-N 3.33Å; V65-K67 PolarHBondContact O-N 2.88Å; V65-I68 WeakPolarHBondContact O-CB 3.43Å; V65-I68 PolarHBondContact O-N 3.45Å; V65-L145 HydrophobicContact CG2-CD2 4.18Å; V65-I189 HydrophobicContact CG2-CG2 3.44Å; V65-I189 VanDerWaalsContact CG2-CG2 3.44Å; V65-Y193 HydrophobicContact CB-CD2 4.2Å; V65-Y193 HydrophobicContact CG1-CD2 4.15Å
66	T	61.3	Low	67.5	Low	91 Å²	91	67.3 Å²	67.3	56%	0.558	34%	0.339	S	S	*	.	H	α-helix	trans	-66.5	-31.5	-174.6	49.3	0	0	0	0	113.2	E64 I68	E64-T66 VanDerWaalsContact C-N 3.28Å; E64-T66 PolarHBondContact O-N 3.18Å; T66-I68 PolarHBondContact O-N 3.05Å
67	K	63	Low	67.2	Low	75 Å²	75	67.6 Å²	67.6	33%	0.326	34%	0.342	S	S	.	.	H	α-helix	trans	-71.9	-13.2	-179.5	-65.5	-169.7	-177.9	165.2	0	113.9	E64 V65 H71 I137	E64-K67 HydrophobicContact CB-CD 4.42Å; E64-K67 HydrophobicContact CB-CG 4.43Å; E64-K67 VanDerWaalsContact CD-NZ 3.27Å; E64-K67 IonicContact OE1-NZ 3.15Å; E64-K67 PolarHBondContact OE1-NZ 2.9Å; E64-K67 VanDerWaalsContact OE1-NZ 3.15Å; E64-K67 VanDerWaalsContact OE2-CD 3.26Å; E64-K67 WeakPolarHBondContact OE2-CD 3.35Å; E64-K67 WeakPolarHBondContact OE2-CE 3.5Å; E64-K67 IonicContact OE2-NZ 2.66Å; E64-K67 PolarHBondContact OE2-NZ 3.2Å; V65-K67 VanDerWaalsContact C-N 3.33Å; V65-K67 PolarHBondContact O-N 2.88Å; K67-H71 PolarHBondContact O-ND1 2.67Å; K67-I137 HydrophobicContact CB-CG2 4.48Å; K67-I137 HydrophobicContact CD-CG2 3.76Å
68	I	61.1	Low	66.8	Low	16 Å²	16	67.5 Å²	67.5	8%	0.082	34%	0.341	C	S	.	.	H	α-helix	trans	-79.3	-37.6	-174.7	-59.9	174.5	0	0	0	111.3	V65 T66 D70 H71 I72 L145	V65-I68 WeakPolarHBondContact O-CB 3.43Å; V65-I68 PolarHBondContact O-N 3.45Å; T66-I68 PolarHBondContact O-N 3.05Å; I68-D70 VanDerWaalsContact C-N 3.29Å; I68-D70 PolarHBondContact O-N 2.98Å; I68-H71 PolarHBondContact O-N 2.82Å; I68-I72 HydrophobicContact CG2-CD1 3.66Å; I68-I72 HydrophobicContact CG2-CG1 3.96Å; I68-I72 WeakPolarHBondContact O-CG1 3.45Å; I68-I72 PolarHBondContact O-N 3.2Å; I68-L145 HydrophobicContact CD1-CB 4.47Å; I68-L145 HydrophobicContact CD1-CD1 3.12Å; I68-L145 HydrophobicContact CD1-CD2 4.49Å; I68-L145 HydrophobicContact CD1-CG 3.46Å; I68-L145 VanDerWaalsContact CD1-CG 3.46Å
69	K	61.5	Low	66.9	Low	174 Å²	174	70.1 Å²	70.1	76%	0.757	36%	0.364	S	S	*	.	H	α-helix	trans	-61.5	-39.1	-177	-168.8	179.5	178.7	-175.2	0	112.1	H71	K69-H71 VanDerWaalsContact C-N 3.29Å; K69-H71 PolarHBondContact O-N 2.93Å
70	D	57	Low	67.2	Low	117 Å²	117	69.9 Å²	69.9	63%	0.626	36%	0.362	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.4	-15.7	-176.3	-61.5	-23.2	0	0	0	113	I68	I68-D70 VanDerWaalsContact C-N 3.29Å; I68-D70 PolarHBondContact O-N 2.98Å
71	H	55.5	Low	67.2	Low	61 Å²	61	70 Å²	70	28%	0.282	36%	0.363	S	S	.	.	T	Hydrogen-bonded Turn	trans	-122.5	-6.9	-169	-68.7	90.2	0	0	0	115.8	K67 I68 K69 L73 K74 V138	K67-H71 PolarHBondContact O-ND1 2.67Å; I68-H71 PolarHBondContact O-N 2.82Å; K69-H71 VanDerWaalsContact C-N 3.29Å; K69-H71 PolarHBondContact O-N 2.93Å; H71-L73 PolarHBondContact O-N 3.31Å; H71-K74 PolarHBondContact O-N 3.43Å; H71-V138 HydrophobicContact CB-CB 4.19Å; H71-V138 HydrophobicContact CB-CG1 3.98Å; H71-V138 HydrophobicContact CB-CG2 3.12Å; H71-V138 WeakPolarHBondContact CD2-CG2 3.39Å
72	I	58.8	Low	67.5	Low	107 Å²	107	72.4 Å²	72.4	55%	0.549	38%	0.375	S	S	.	.	T	Hydrogen-bonded Turn	trans	-53.9	-15.7	167.7	-92.5	173.3	0	0	0	112.6	I68 K74	I68-I72 HydrophobicContact CG2-CD1 3.66Å; I68-I72 HydrophobicContact CG2-CG1 3.96Å; I68-I72 WeakPolarHBondContact O-CG1 3.45Å; I68-I72 PolarHBondContact O-N 3.2Å; I72-K74 PolarHBondContact O-N 3Å
73	L	54.8	Low	68.4	Low	147 Å²	147	73.8 Å²	73.8	77%	0.77	38%	0.38	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.5	-8.6	177.7	-64.3	168.9	0	0	0	115	H71 P75	H71-L73 PolarHBondContact O-N 3.31Å; L73-P75 VanDerWaalsContact C-CD 3.5Å; L73-P75 VanDerWaalsContact O-CD 3.27Å; L73-P75 WeakPolarHBondContact O-CD 3.31Å
74	K	64.8	Low	69.2	Low	130 Å²	130	73.3 Å²	73.3	57%	0.565	38%	0.378	S	S	*	.			trans	-114.3	74.3	174.9	-68.2	-170.2	179.9	-176.1	0	112.6	H71 I72 K76 G77	H71-K74 PolarHBondContact O-N 3.43Å; I72-K74 PolarHBondContact O-N 3Å; K74-K76 VanDerWaalsContact C-N 3.28Å; K74-K76 PolarHBondContact O-N 3.49Å; K74-K76 VanDerWaalsContact O-N 3.15Å; K74-G77 PolarHBondContact O-N 3.1Å
75	P	71.4	Confident	70.3	Confident	91 Å²	91	69.1 Å²	69.1	59%	0.591	36%	0.358	S	S	*	.	H	α-helix	trans	-62.8	-28	-169.6	23.9	-34.9	0	0	0	114.5	L73 V78 A79	L73-P75 VanDerWaalsContact C-CD 3.5Å; L73-P75 VanDerWaalsContact O-CD 3.27Å; L73-P75 WeakPolarHBondContact O-CD 3.31Å; P75-V78 PolarHBondContact O-N 2.93Å; P75-A79 PolarHBondContact O-N 3.32Å
76	K	73.2	Confident	71.6	Confident	174 Å²	174	67.9 Å²	67.9	76%	0.757	35%	0.35	S	S	*	.	H	α-helix	trans	-65.2	-42.2	-179.3	-66.6	-175.5	178.8	-179.6	0	112.6	K74 I80	K74-K76 VanDerWaalsContact C-N 3.28Å; K74-K76 PolarHBondContact O-N 3.49Å; K74-K76 VanDerWaalsContact O-N 3.15Å; K76-I80 WeakPolarHBondContact O-CD1 3.36Å; K76-I80 VanDerWaalsContact O-CG1 3.23Å; K76-I80 WeakPolarHBondContact O-CG1 3.46Å; K76-I80 PolarHBondContact O-N 3.49Å
77	G	70.7	Confident	72.9	Confident	6 Å²	6	64.8 Å²	64.8	6%	0.062	34%	0.336	C	S	.	.	H	α-helix	trans	-67.6	-39.8	178.6	0	0	0	0	0	112.2	K74 I80 A81	K74-G77 PolarHBondContact O-N 3.1Å; G77-I80 PolarHBondContact O-N 3.29Å; G77-A81 WeakPolarHBondContact O-CB 3.43Å; G77-A81 PolarHBondContact O-N 3.4Å
78	V	73.6	Confident	74.3	Confident	26 Å²	26	62.2 Å²	62.2	16%	0.158	33%	0.326	C	S	.	.	H	α-helix	trans	-64	-46.5	177.3	179.3	0	0	0	0	111.4	P75 I80 A81 I82 V138 C142	P75-V78 PolarHBondContact O-N 2.93Å; V78-I80 VanDerWaalsContact C-N 3.28Å; V78-I80 PolarHBondContact O-N 3.29Å; V78-A81 WeakPolarHBondContact O-CB 3.41Å; V78-A81 PolarHBondContact O-N 3.23Å; V78-I82 HydrophobicContact CG1-CD1 3.93Å; V78-I82 HydrophobicContact CG1-CG1 4.47Å; V78-I82 VanDerWaalsContact O-CG1 3.3Å; V78-I82 WeakPolarHBondContact O-CG1 3.29Å; V78-I82 PolarHBondContact O-N 3.37Å; V78-V138 HydrophobicContact CG2-CG1 3.95Å; V78-C142 HydrophobicContact CG1-CB 4.3Å
79	A	82.6	Confident	75.8	Confident	59 Å²	59	61.5 Å²	61.5	49%	0.488	32%	0.322	S	S	.	.	H	α-helix	trans	-59.6	-40.4	178.8	0	0	0	0	0	112.2	P75 I82 L83	P75-A79 PolarHBondContact O-N 3.32Å; A79-I82 PolarHBondContact O-N 2.95Å; A79-L83 WeakPolarHBondContact O-CB 3.47Å; A79-L83 PolarHBondContact O-N 3.33Å
80	I	81.9	Confident	77.3	Confident	5 Å²	5	53.2 Å²	53.2	3%	0.026	29%	0.286	C	S	.	.	H	α-helix	trans	-68.9	-39	178.7	-64.7	168	0	0	0	110.8	K76 G77 V78 I82 L83 S84 I255 F259 L261 V269	K76-I80 WeakPolarHBondContact O-CD1 3.36Å; K76-I80 VanDerWaalsContact O-CG1 3.23Å; K76-I80 WeakPolarHBondContact O-CG1 3.46Å; K76-I80 PolarHBondContact O-N 3.49Å; G77-I80 PolarHBondContact O-N 3.29Å; V78-I80 VanDerWaalsContact C-N 3.28Å; V78-I80 PolarHBondContact O-N 3.29Å; I80-I82 VanDerWaalsContact C-N 3.35Å; I80-L83 PolarHBondContact O-N 3.46Å; I80-S84 WeakPolarHBondContact O-CB 3.43Å; I80-S84 PolarHBondContact O-N 2.93Å; I80-S84 PolarHBondContact O-OG 3.47Å; I80-I255 HydrophobicContact CG2-CG2 4.16Å; I80-F259 HydrophobicContact CD1-CB 3.41Å; I80-F259 VanDerWaalsContact CD1-CB 3.41Å; I80-F259 HydrophobicContact CD1-CD1 4.15Å; I80-F259 HydrophobicContact CD1-CD2 3.94Å; I80-F259 HydrophobicContact CD1-CG 3.58Å; I80-F259 HydrophobicContact CG1-CB 4.23Å; I80-F259 HydrophobicContact CG1-CD1 4.27Å; I80-F259 HydrophobicContact CG1-CD2 3.8Å; I80-F259 HydrophobicContact CG1-CE2 4.24Å; I80-F259 HydrophobicContact CG1-CG 3.84Å; I80-L261 HydrophobicContact CD1-CD1 3.22Å; I80-L261 HydrophobicContact CD1-CD2 4.41Å; I80-L261 HydrophobicContact CD1-CG 4.23Å; I80-V269 HydrophobicContact CG2-CG1 3.87Å; I80-V269 HydrophobicContact CG2-CG2 4.33Å
81	A	74.4	Confident	79.1	Confident	2 Å²	2	51.7 Å²	51.7	2%	0.017	28%	0.277	C	S	.	.	H	α-helix	trans	-60.2	-44.3	173.9	0	0	0	0	0	112.2	G77 V78 L83 S84 Q85 M139	G77-A81 WeakPolarHBondContact O-CB 3.43Å; G77-A81 PolarHBondContact O-N 3.4Å; V78-A81 WeakPolarHBondContact O-CB 3.41Å; V78-A81 PolarHBondContact O-N 3.23Å; A81-L83 VanDerWaalsContact C-N 3.35Å; A81-S84 PolarHBondContact O-OG 3.35Å; A81-Q85 WeakPolarHBondContact O-CB 3.48Å; A81-Q85 PolarHBondContact O-N 3.44Å; A81-M139 VanDerWaalsContact CA-CE 3.47Å; A81-M139 HydrophobicContact CB-CB 3.79Å; A81-M139 HydrophobicContact CB-CE 3.37Å; A81-M139 HydrophobicContact CB-CG 3.63Å; A81-M139 HydrophobicContact CB-SD 4.29Å
82	I	83.9	Confident	80.9	Confident	53 Å²	53	49.6 Å²	49.6	27%	0.272	27%	0.269	S	S	.	.	H	α-helix	trans	-64.4	-45.4	178.5	-64.6	170.9	0	0	0	109.8	V78 A79 I80 Y86 L146	V78-I82 HydrophobicContact CG1-CD1 3.93Å; V78-I82 HydrophobicContact CG1-CG1 4.47Å; V78-I82 VanDerWaalsContact O-CG1 3.3Å; V78-I82 WeakPolarHBondContact O-CG1 3.29Å; V78-I82 PolarHBondContact O-N 3.37Å; A79-I82 PolarHBondContact O-N 2.95Å; I80-I82 VanDerWaalsContact C-N 3.35Å; I82-Y86 HydrophobicContact CG2-CD2 4.45Å; I82-Y86 WeakPolarHBondContact O-CB 3.45Å; I82-Y86 PolarHBondContact O-N 3.35Å; I82-L146 HydrophobicContact CD1-CD2 3.68Å; I82-L146 HydrophobicContact CG1-CD2 3.84Å; I82-L146 HydrophobicContact CG2-CD2 4.2Å
83	L	89.1	Confident	82.6	Confident	81 Å²	81	44.5 Å²	44.5	42%	0.424	24%	0.243	S	C	.	.	I	π-helix	trans	-65.6	-41.9	-179.7	-176.7	58.2	0	0	0	112.4	A79 I80 A81 G87 I88 I255 F259	A79-L83 WeakPolarHBondContact O-CB 3.47Å; A79-L83 PolarHBondContact O-N 3.33Å; I80-L83 PolarHBondContact O-N 3.46Å; A81-L83 VanDerWaalsContact C-N 3.35Å; L83-G87 WeakPolarHBondContact O-CA 3.29Å; L83-G87 PolarHBondContact O-N 2.97Å; L83-I88 PolarHBondContact O-N 3.25Å; L83-I255 HydrophobicContact CD2-CD1 3.53Å; L83-I255 HydrophobicContact CD2-CG1 4.48Å; L83-I255 HydrophobicContact CG-CD1 3.73Å; L83-F259 HydrophobicContact CD2-CE2 4.02Å; L83-F259 HydrophobicContact CD2-CZ 4.18Å
84	S	85.8	Confident	84.4	Confident	0 Å²	0	39.6 Å²	39.6	0%	0	22%	0.216	C	C	.	.	I	π-helix	trans	-72.4	-43.9	178.7	72.9	0	0	0	0	111.7	I80 A81 I88 M89 T273	I80-S84 WeakPolarHBondContact O-CB 3.43Å; I80-S84 PolarHBondContact O-N 2.93Å; I80-S84 PolarHBondContact O-OG 3.47Å; A81-S84 PolarHBondContact O-OG 3.35Å; S84-I88 WeakPolarHBondContact O-CB 3.11Å; S84-I88 PolarHBondContact O-N 2.85Å; S84-M89 PolarHBondContact O-N 2.87Å; S84-T273 VanDerWaalsContact CB-OG1 3.24Å; S84-T273 WeakPolarHBondContact CB-OG1 3.36Å; S84-T273 PolarHBondContact OG-OG1 3.25Å
85	Q	88.9	Confident	85.8	Confident	2 Å²	2	36.9 Å²	36.9	1%	0.009	21%	0.212	C	C	.	.	I	π-helix	trans	-76.3	-40.3	-175.2	-159.6	67.4	29.3	0	0	113.4	A81 P90 C116 E272 Q276	A81-Q85 WeakPolarHBondContact O-CB 3.48Å; A81-Q85 PolarHBondContact O-N 3.44Å; Q85-P90 VanDerWaalsContact O-CD 3.24Å; Q85-P90 WeakPolarHBondContact O-CD 3.21Å; Q85-C116 PolarHBondContact NE2-O 2.84Å; Q85-E272 PolarHBondContact OE1-O 3.45Å; Q85-Q276 VanDerWaalsContact NE2-CD 3.28Å
86	Y	89.7	Confident	86.9	Confident	8 Å²	8	33.5 Å²	33.5	3%	0.031	19%	0.189	C	C	.	.	I	π-helix	trans	-109.3	-10.5	-174.9	-67.3	-58.4	0	0	0	114.2	I82 P90 S143 L146 A147 M150 L154	I82-Y86 HydrophobicContact CG2-CD2 4.45Å; I82-Y86 WeakPolarHBondContact O-CB 3.45Å; I82-Y86 PolarHBondContact O-N 3.35Å; Y86-P90 WeakPolarHBondContact O-CG 3.23Å; Y86-S143 PolarHBondContact OH-O 3.07Å; Y86-L146 HydrophobicContact CD2-CB 4.48Å; Y86-L146 HydrophobicContact CE2-CB 3.77Å; Y86-A147 WeakPolarHBondContact OH-CA 3.34Å; Y86-A147 WeakPolarHBondContact OH-CB 3.44Å; Y86-A147 PolarHBondContact OH-N 2.6Å; Y86-A147 VanDerWaalsContact OH-N 3.12Å; Y86-M150 HydrophobicContact CD1-CB 3.64Å; Y86-M150 HydrophobicContact CD1-CG 4.42Å; Y86-M150 HydrophobicContact CD2-CB 4.14Å; Y86-M150 HydrophobicContact CD2-CG 4.08Å; Y86-M150 HydrophobicContact CE1-CB 3.74Å; Y86-M150 HydrophobicContact CE2-CB 4.22Å; Y86-M150 HydrophobicContact CE2-CG 4.32Å; Y86-M150 HydrophobicContact CG-CB 3.86Å; Y86-M150 HydrophobicContact CG-CE 4.13Å; Y86-M150 HydrophobicContact CG-CG 4.15Å; Y86-L154 HydrophobicContact CD1-CD1 3.54Å; Y86-L154 HydrophobicContact CG-CD1 4.15Å
87	G	89.8	Confident	87.8	Confident	26 Å²	26	25.2 Å²	25.2	27%	0.268	15%	0.153	S	C	.	.	I	π-helix	trans	-93.8	-64.9	168.4	0	0	0	0	0	111.2	L83 L91	L83-G87 WeakPolarHBondContact O-CA 3.29Å; L83-G87 PolarHBondContact O-N 2.97Å; G87-L91 WeakPolarHBondContact O-CB 3.08Å; G87-L91 PolarHBondContact O-N 3.14Å
88	I	91.2	Very high	88.7	Confident	22 Å²	22	29.1 Å²	29.1	11%	0.113	17%	0.168	C	C	.	.	I	π-helix	trans	-71.1	-51	-167.7	-57.9	171.6	0	0	0	112.3	L83 S84 L91 T92 F251 I255	L83-I88 PolarHBondContact O-N 3.25Å; S84-I88 WeakPolarHBondContact O-CB 3.11Å; S84-I88 PolarHBondContact O-N 2.85Å; I88-L91 PolarHBondContact O-N 3.43Å; I88-T92 VanDerWaalsContact O-CB 3.31Å; I88-T92 WeakPolarHBondContact O-CB 3.37Å; I88-T92 PolarHBondContact O-N 3.2Å; I88-T92 PolarHBondContact O-OG1 2.89Å; I88-F251 HydrophobicContact CD1-CB 3.94Å; I88-F251 HydrophobicContact CG2-CB 3.7Å; I88-F251 HydrophobicContact CG2-CD1 4.41Å; I88-F251 HydrophobicContact CG2-CG 4.03Å; I88-I255 HydrophobicContact CD1-CB 4.38Å; I88-I255 HydrophobicContact CD1-CD1 3.75Å; I88-I255 HydrophobicContact CD1-CG2 4.29Å
89	M	93.6	Very high	89.5	Confident	0 Å²	0	30.8 Å²	30.8	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-65.3	-45.1	-173.5	-68.2	-66.2	-81.9	0	0	113.5	S84 L91 T92 A93 G114 L244 G248 T273 Q276	S84-M89 PolarHBondContact O-N 2.87Å; M89-L91 PolarHBondContact O-N 3.48Å; M89-T92 PolarHBondContact O-N 3.21Å; M89-A93 PolarHBondContact O-N 3.33Å; M89-G114 CarbonylContact C-O 3.55Å; M89-G114 VanDerWaalsContact CB-O 3.25Å; M89-G114 WeakPolarHBondContact CB-O 3.32Å; M89-L244 HydrophobicContact CE-CG 4.22Å; M89-G248 WeakPolarHBondContact SD-CA 3.43Å; M89-T273 WeakPolarHBondContact CE-O 3.16Å; M89-T273 HydrophobicContact CG-CG2 3.87Å; M89-T273 WeakPolarHBondContact CG-O 3.48Å; M89-T273 HydrophobicContact SD-CG2 4.24Å; M89-Q276 HydrophobicContact CE-CG 3.69Å
90	P	92.8	Very high	89.9	Confident	0 Å²	0	31.8 Å²	31.8	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-63.1	-42.3	174.5	-25.7	35.9	0	0	0	112.7	Q85 Y86 T92 A93 F94 G114 L154 Y158	Q85-P90 VanDerWaalsContact O-CD 3.24Å; Q85-P90 WeakPolarHBondContact O-CD 3.21Å; Y86-P90 WeakPolarHBondContact O-CG 3.23Å; P90-T92 VanDerWaalsContact C-N 3.32Å; P90-T92 PolarHBondContact O-N 2.77Å; P90-A93 PolarHBondContact O-N 2.85Å; P90-F94 WeakPolarHBondContact O-CB 3.05Å; P90-F94 PolarHBondContact O-N 2.93Å; P90-G114 WeakPolarHBondContact CD-O 3.22Å; P90-L154 HydrophobicContact CB-CD1 4.34Å; P90-L154 HydrophobicContact CG-CD1 3.77Å; P90-Y158 HydrophobicContact CB-CD2 4.18Å; P90-Y158 HydrophobicContact CB-CE2 3.53Å
91	L	94	Very high	90.2	Very high	85 Å²	85	40 Å²	40	45%	0.445	22%	0.222	S	C	.	.	H	α-helix	trans	-63.7	-41.7	177.8	-178.1	61.9	0	0	0	111	G87 I88 M89 F94 C95 Y158	G87-L91 WeakPolarHBondContact O-CB 3.08Å; G87-L91 PolarHBondContact O-N 3.14Å; I88-L91 PolarHBondContact O-N 3.43Å; M89-L91 PolarHBondContact O-N 3.48Å; L91-F94 PolarHBondContact O-N 3.21Å; L91-C95 WeakPolarHBondContact O-CB 3.44Å; L91-C95 PolarHBondContact O-N 3.27Å; L91-C95 PolarHBondContact O-SG 3.5Å; L91-Y158 WeakPolarHBondContact CA-OH 3.36Å; L91-Y158 WeakPolarHBondContact CB-OH 3.35Å; L91-Y158 HydrophobicContact CD1-CE1 4.26Å; L91-Y158 PolarHBondContact N-OH 3.43Å
92	T	94.6	Very high	90.8	Very high	17 Å²	17	41.3 Å²	41.3	10%	0.104	23%	0.229	C	C	.	.	H	α-helix	trans	-61.5	-48	176.1	-59	0	0	0	0	110.6	I88 M89 P90 F94 C95 L96 L244 I247	I88-T92 VanDerWaalsContact O-CB 3.31Å; I88-T92 WeakPolarHBondContact O-CB 3.37Å; I88-T92 PolarHBondContact O-N 3.2Å; I88-T92 PolarHBondContact O-OG1 2.89Å; M89-T92 PolarHBondContact O-N 3.21Å; P90-T92 VanDerWaalsContact C-N 3.32Å; P90-T92 PolarHBondContact O-N 2.77Å; T92-F94 VanDerWaalsContact C-N 3.31Å; T92-F94 PolarHBondContact O-N 3.45Å; T92-C95 PolarHBondContact O-N 3.45Å; T92-L96 HydrophobicContact CG2-CD1 3.81Å; T92-L96 HydrophobicContact CG2-CG 4.21Å; T92-L96 WeakPolarHBondContact O-CB 3.3Å; T92-L96 VanDerWaalsContact O-CG 3.26Å; T92-L96 WeakPolarHBondContact O-CG 3.49Å; T92-L96 PolarHBondContact O-N 3.45Å; T92-L244 HydrophobicContact CG2-CD1 3.8Å; T92-I247 HydrophobicContact CG2-CB 3.94Å; T92-I247 HydrophobicContact CG2-CD1 3.7Å; T92-I247 HydrophobicContact CG2-CG1 4.44Å; T92-I247 HydrophobicContact CG2-CG2 3.58Å
93	A	94.4	Very high	90.8	Very high	0 Å²	0	42.2 Å²	42.2	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-58.6	-42.4	175.9	0	0	0	0	0	111.8	M89 P90 T97 I110 L111 L244	M89-A93 PolarHBondContact O-N 3.33Å; P90-A93 PolarHBondContact O-N 2.85Å; A93-T97 WeakPolarHBondContact O-CB 3.24Å; A93-T97 WeakPolarHBondContact O-CG2 3.25Å; A93-T97 PolarHBondContact O-N 3.46Å; A93-T97 PolarHBondContact O-OG1 2.91Å; A93-I110 HydrophobicContact CB-CG2 4.11Å; A93-L111 HydrophobicContact CB-CD2 4.17Å; A93-L244 HydrophobicContact CB-CD1 4Å
94	F	92.8	Very high	90.5	Very high	45 Å²	45	40.2 Å²	40.2	20%	0.197	23%	0.229	C	C	.	.	H	α-helix	trans	-63.1	-48.4	175.6	-178.3	-103.4	0	0	0	112.7	P90 L91 T92 L96 T97 K98 L111 Y158 F162	P90-F94 WeakPolarHBondContact O-CB 3.05Å; P90-F94 PolarHBondContact O-N 2.93Å; L91-F94 PolarHBondContact O-N 3.21Å; T92-F94 VanDerWaalsContact C-N 3.31Å; T92-F94 PolarHBondContact O-N 3.45Å; F94-L96 PolarHBondContact O-N 2.91Å; F94-T97 WeakPolarHBondContact CA-OG1 3.4Å; F94-T97 PolarHBondContact O-N 2.73Å; F94-T97 PolarHBondContact O-OG1 3.35Å; F94-K98 HydrophobicContact CE1-CG 4.16Å; F94-K98 HydrophobicContact CE2-CG 4.18Å; F94-K98 HydrophobicContact CZ-CG 3.99Å; F94-K98 WeakPolarHBondContact O-CB 3.49Å; F94-K98 WeakPolarHBondContact O-CG 3.18Å; F94-K98 PolarHBondContact O-N 3.06Å; F94-L111 HydrophobicContact CB-CD2 3.95Å; F94-Y158 HydrophobicContact CB-CD1 3.49Å; F94-Y158 VanDerWaalsContact CB-CD1 3.49Å; F94-Y158 HydrophobicContact CB-CE1 3.65Å; F94-Y158 HydrophobicContact CB-CG 4.27Å; F94-Y158 HydrophobicContact CD1-CD1 4.02Å; F94-Y158 HydrophobicContact CD1-CE1 4.11Å; F94-Y158 AromaticContact CD2-CD1 3.47Å; F94-Y158 HydrophobicContact CD2-CD1 3.47Å; F94-Y158 VanDerWaalsContact CD2-CD1 3.47Å; F94-Y158 HydrophobicContact CD2-CE1 4.32Å; F94-Y158 HydrophobicContact CD2-CG 4.18Å; F94-Y158 HydrophobicContact CE2-CD1 4.14Å; F94-Y158 AromaticContact CG-CD1 3.37Å; F94-Y158 HydrophobicContact CG-CD1 3.37Å; F94-Y158 AromaticContact CG-CE1 3.78Å; F94-Y158 HydrophobicContact CG-CE1 3.78Å; F94-Y158 HydrophobicContact CG-CG 4.36Å; F94-F162 AromaticContact CD2-CE2 3.8Å; F94-F162 HydrophobicContact CD2-CE2 3.8Å; F94-F162 AromaticContact CD2-CZ 4Å; F94-F162 HydrophobicContact CD2-CZ 4Å; F94-F162 HydrophobicContact CE2-CD2 4.34Å; F94-F162 AromaticContact CE2-CE2 3.6Å; F94-F162 HydrophobicContact CE2-CE2 3.6Å; F94-F162 AromaticContact CE2-CZ 3.91Å; F94-F162 HydrophobicContact CE2-CZ 3.91Å
95	C	94	Very high	90.2	Very high	72 Å²	72	41.9 Å²	41.9	49%	0.486	24%	0.242	S	C	.	.	H	α-helix	trans	-62.7	-42.6	179.3	-71.3	0	0	0	0	111.9	L91 T92 G99	L91-C95 WeakPolarHBondContact O-CB 3.44Å; L91-C95 PolarHBondContact O-N 3.27Å; L91-C95 PolarHBondContact O-SG 3.5Å; T92-C95 PolarHBondContact O-N 3.45Å; C95-G99 PolarHBondContact O-N 3.48Å
96	L	94	Very high	90	Very high	20 Å²	20	42.7 Å²	42.7	11%	0.105	25%	0.247	C	C	.	.	H	α-helix	trans	-64.8	-47.3	177.4	-71.8	175.8	0	0	0	111.3	T92 F94 K98 G99 F100 I240 L243 L244 I247	T92-L96 HydrophobicContact CG2-CD1 3.81Å; T92-L96 HydrophobicContact CG2-CG 4.21Å; T92-L96 WeakPolarHBondContact O-CB 3.3Å; T92-L96 VanDerWaalsContact O-CG 3.26Å; T92-L96 WeakPolarHBondContact O-CG 3.49Å; T92-L96 PolarHBondContact O-N 3.45Å; F94-L96 PolarHBondContact O-N 2.91Å; L96-K98 VanDerWaalsContact C-N 3.32Å; L96-K98 PolarHBondContact O-N 3.33Å; L96-G99 PolarHBondContact O-N 3.32Å; L96-F100 HydrophobicContact CD2-CE2 4.08Å; L96-F100 VanDerWaalsContact O-CD2 3.3Å; L96-F100 WeakPolarHBondContact O-CD2 3.4Å; L96-F100 PolarHBondContact O-N 3.4Å; L96-I240 HydrophobicContact CB-CD1 4.37Å; L96-I240 HydrophobicContact CB-CG1 4.16Å; L96-I240 HydrophobicContact CD1-CG2 4.22Å; L96-L243 HydrophobicContact CD1-CB 4.14Å; L96-L243 HydrophobicContact CD2-CB 4.21Å; L96-L243 HydrophobicContact CD2-CD1 3.96Å; L96-L244 HydrophobicContact CD1-CB 4.14Å; L96-L244 HydrophobicContact CD1-CD1 4.13Å; L96-I247 HydrophobicContact CD1-CD1 4.45Å; L96-I247 HydrophobicContact CD2-CD1 4.46Å
97	T	91.7	Very high	89.9	Confident	1 Å²	1	42.4 Å²	42.4	1%	0.006	25%	0.246	C	C	.	.	H	α-helix	trans	-63	-38.1	-179.9	52.4	0	0	0	0	112.7	A93 F94 Q101 L102 A107 I110	A93-T97 WeakPolarHBondContact O-CB 3.24Å; A93-T97 WeakPolarHBondContact O-CG2 3.25Å; A93-T97 PolarHBondContact O-N 3.46Å; A93-T97 PolarHBondContact O-OG1 2.91Å; F94-T97 WeakPolarHBondContact CA-OG1 3.4Å; F94-T97 PolarHBondContact O-N 2.73Å; F94-T97 PolarHBondContact O-OG1 3.35Å; T97-Q101 PolarHBondContact O-N 2.9Å; T97-L102 HydrophobicContact CG2-CD1 4.04Å; T97-L102 PolarHBondContact O-N 3.31Å; T97-A107 HydrophobicContact CG2-CB 4.03Å; T97-I110 HydrophobicContact CG2-CB 3.61Å; T97-I110 HydrophobicContact CG2-CD1 3.9Å; T97-I110 HydrophobicContact CG2-CG1 4.38Å; T97-I110 HydrophobicContact CG2-CG2 3.5Å; T97-I110 VanDerWaalsContact CG2-CG2 3.5Å
98	K	89.3	Confident	89.6	Confident	87 Å²	87	41.4 Å²	41.4	38%	0.378	24%	0.235	S	C	.	.	H	α-helix	trans	-69.4	-44.9	172.7	-74.3	-69	-170.3	176	0	112.7	F94 L96 F100 Q101 G161 F162	F94-K98 HydrophobicContact CE1-CG 4.16Å; F94-K98 HydrophobicContact CE2-CG 4.18Å; F94-K98 HydrophobicContact CZ-CG 3.99Å; F94-K98 WeakPolarHBondContact O-CB 3.49Å; F94-K98 WeakPolarHBondContact O-CG 3.18Å; F94-K98 PolarHBondContact O-N 3.06Å; L96-K98 VanDerWaalsContact C-N 3.32Å; L96-K98 PolarHBondContact O-N 3.33Å; K98-F100 VanDerWaalsContact C-N 3.35Å; K98-F100 PolarHBondContact O-N 3.48Å; K98-Q101 PolarHBondContact O-N 3.21Å; K98-Q101 VanDerWaalsContact O-N 3.13Å; K98-G161 VanDerWaalsContact CE-O 3.3Å; K98-G161 WeakPolarHBondContact CE-O 3.2Å; K98-G161 PolarHBondContact NZ-O 3.35Å; K98-F162 HydrophobicContact CD-CE1 3.95Å; K98-F162 HydrophobicContact CD-CZ 4.38Å; K98-F162 HydrophobicContact CG-CE1 4.43Å; K98-F162 HydrophobicContact CG-CZ 4.44Å
99	G	91.6	Very high	89.5	Confident	61 Å²	61	40.3 Å²	40.3	63%	0.629	23%	0.23	S	C	*	.	H	α-helix	trans	-62.6	-40.2	-178.9	0	0	0	0	0	112.9	C95 L96 Q101	C95-G99 PolarHBondContact O-N 3.48Å; L96-G99 PolarHBondContact O-N 3.32Å; G99-Q101 VanDerWaalsContact C-N 3.31Å
100	F	90.9	Very high	89.4	Confident	80 Å²	80	40.3 Å²	40.3	35%	0.351	23%	0.23	S	C	.	.	T	Hydrogen-bonded Turn	trans	-85.8	3.1	176.2	-74.3	-78.7	0	0	0	114	L96 K98 L102 P236 A239 I240 L243	L96-F100 HydrophobicContact CD2-CE2 4.08Å; L96-F100 VanDerWaalsContact O-CD2 3.3Å; L96-F100 WeakPolarHBondContact O-CD2 3.4Å; L96-F100 PolarHBondContact O-N 3.4Å; K98-F100 VanDerWaalsContact C-N 3.35Å; K98-F100 PolarHBondContact O-N 3.48Å; F100-L102 VanDerWaalsContact C-N 3.28Å; F100-L102 HydrophobicContact CB-CD2 4.01Å; F100-L102 HydrophobicContact CB-CG 4.08Å; F100-L102 PolarHBondContact O-N 3.14Å; F100-P236 HydrophobicContact CB-CB 4.19Å; F100-P236 HydrophobicContact CD1-CB 3.67Å; F100-P236 HydrophobicContact CE1-CB 4.36Å; F100-P236 HydrophobicContact CG-CB 4.15Å; F100-A239 HydrophobicContact CE1-CB 4.06Å; F100-A239 HydrophobicContact CE2-CB 4.45Å; F100-A239 HydrophobicContact CZ-CB 3.71Å; F100-I240 HydrophobicContact CB-CD1 4.21Å; F100-I240 HydrophobicContact CD2-CD1 3.76Å; F100-I240 HydrophobicContact CD2-CG1 3.65Å; F100-I240 HydrophobicContact CE2-CD1 4.49Å; F100-I240 HydrophobicContact CE2-CG1 3.89Å; F100-I240 HydrophobicContact CG-CD1 4.17Å; F100-I240 HydrophobicContact CG-CG1 4.38Å; F100-L243 HydrophobicContact CE2-CD1 4.15Å; F100-L243 HydrophobicContact CZ-CD1 4.26Å
101	Q	88.3	Confident	89.3	Confident	177 Å²	177	40.3 Å²	40.3	83%	0.827	23%	0.23	S	C	*	.	T	Hydrogen-bonded Turn	trans	50.2	44.4	177.3	-57.6	-179.2	9.3	0	0	113.6	T97 K98 G99	T97-Q101 PolarHBondContact O-N 2.9Å; K98-Q101 PolarHBondContact O-N 3.21Å; K98-Q101 VanDerWaalsContact O-N 3.13Å; G99-Q101 VanDerWaalsContact C-N 3.31Å
102	L	85.6	Confident	89	Confident	30 Å²	30	36.3 Å²	36.3	16%	0.157	21%	0.208	C	C	.	.			trans	-70.4	157.1	-176	-58.8	-180	0	0	0	112.4	T97 F100 T106 I110 P236 L237 I240	T97-L102 HydrophobicContact CG2-CD1 4.04Å; T97-L102 PolarHBondContact O-N 3.31Å; F100-L102 VanDerWaalsContact C-N 3.28Å; F100-L102 HydrophobicContact CB-CD2 4.01Å; F100-L102 HydrophobicContact CB-CG 4.08Å; F100-L102 PolarHBondContact O-N 3.14Å; L102-T106 HydrophobicContact CB-CG2 4.13Å; L102-T106 HydrophobicContact CD1-CG2 3.79Å; L102-T106 HydrophobicContact CG-CG2 4.39Å; L102-I110 HydrophobicContact CD1-CD1 3.2Å; L102-P236 HydrophobicContact CD2-CB 4.1Å; L102-P236 HydrophobicContact CD2-CG 4.43Å; L102-L237 HydrophobicContact CD1-CD2 4.39Å; L102-I240 HydrophobicContact CD1-CD1 3.47Å; L102-I240 VanDerWaalsContact CD1-CD1 3.47Å; L102-I240 HydrophobicContact CG-CD1 4.33Å
103	S	85.1	Confident	88.8	Confident	73 Å²	73	35.5 Å²	35.5	51%	0.51	20%	0.204	S	C	.	.			trans	-60.6	151.4	169.6	70.3	0	0	0	0	110.9	A105 T106 A107	S103-A105 PolarHBondContact O-N 3.47Å; S103-T106 WeakPolarHBondContact O-CB 3.36Å; S103-T106 PolarHBondContact O-N 2.86Å; S103-T106 VanDerWaalsContact O-N 3.11Å; S103-T106 WeakPolarHBondContact OG-CB 3.33Å; S103-T106 PolarHBondContact OG-OG1 3.02Å; S103-A107 PolarHBondContact O-N 2.9Å
104	E	81.6	Confident	88.7	Confident	39 Å²	39	35.5 Å²	35.5	18%	0.182	20%	0.204	C	C	.	.	H	α-helix	trans	-62.6	-41.9	-171.5	-64.9	-166.4	143.6	0	0	113.2	T106 A107 V108 N164 L165	E104-T106 VanDerWaalsContact C-N 3.3Å; E104-T106 PolarHBondContact O-N 3.41Å; E104-A107 PolarHBondContact O-N 3.27Å; E104-V108 WeakPolarHBondContact O-CG2 3.38Å; E104-V108 PolarHBondContact O-N 3.39Å; E104-N164 VanDerWaalsContact OE1-CA 3.23Å; E104-N164 WeakPolarHBondContact OE1-CA 3.28Å; E104-N164 WeakPolarHBondContact OE1-CB 3.26Å; E104-N164 PolarHBondContact OE1-N 3.19Å; E104-N164 VanDerWaalsContact OE1-N 3.15Å; E104-L165 HydrophobicContact CB-CD1 3.59Å; E104-L165 HydrophobicContact CG-CD1 4.28Å; E104-L165 PolarHBondContact OE1-N 2.76Å; E104-L165 VanDerWaalsContact OE2-CA 3.28Å; E104-L165 WeakPolarHBondContact OE2-CA 3.01Å; E104-L165 PolarHBondContact OE2-N 3.49Å
105	A	79.4	Confident	88.6	Confident	35 Å²	35	33.3 Å²	33.3	29%	0.289	19%	0.194	S	C	.	.	H	α-helix	trans	-60	-41.5	175	0	0	0	0	0	111.9	S103 V108 V109	S103-A105 PolarHBondContact O-N 3.47Å; A105-V108 PolarHBondContact O-N 2.88Å; A105-V109 WeakPolarHBondContact O-CG2 3.49Å; A105-V109 PolarHBondContact O-N 2.72Å
106	T	85.3	Confident	88.2	Confident	19 Å²	19	29.9 Å²	29.9	12%	0.117	17%	0.171	C	C	.	.	H	α-helix	trans	-65.1	-43.3	176.4	-56.9	0	0	0	0	111.3	L102 S103 E104 V108 V109 I110 L237 M297	L102-T106 HydrophobicContact CB-CG2 4.13Å; L102-T106 HydrophobicContact CD1-CG2 3.79Å; L102-T106 HydrophobicContact CG-CG2 4.39Å; S103-T106 WeakPolarHBondContact O-CB 3.36Å; S103-T106 PolarHBondContact O-N 2.86Å; S103-T106 VanDerWaalsContact O-N 3.11Å; S103-T106 WeakPolarHBondContact OG-CB 3.33Å; S103-T106 PolarHBondContact OG-OG1 3.02Å; E104-T106 VanDerWaalsContact C-N 3.3Å; E104-T106 PolarHBondContact O-N 3.41Å; T106-V108 VanDerWaalsContact C-N 3.33Å; T106-V108 PolarHBondContact O-N 3.34Å; T106-V109 PolarHBondContact O-N 2.95Å; T106-I110 HydrophobicContact CG2-CD1 3.96Å; T106-I110 PolarHBondContact O-N 3.47Å; T106-I110 VanDerWaalsContact O-N 3.08Å; T106-L237 HydrophobicContact CG2-CD2 3.62Å; T106-M297 HydrophobicContact CG2-CE 3.58Å; T106-M297 HydrophobicContact CG2-SD 3.91Å
107	A	87.7	Confident	87.9	Confident	1 Å²	1	29 Å²	29	1%	0.008	17%	0.166	C	C	.	.	H	α-helix	trans	-61.5	-41.4	179.7	0	0	0	0	0	111.7	T97 S103 E104 I110 L111 F162	T97-A107 HydrophobicContact CG2-CB 4.03Å; S103-A107 PolarHBondContact O-N 2.9Å; E104-A107 PolarHBondContact O-N 3.27Å; A107-I110 PolarHBondContact O-N 3.29Å; A107-L111 WeakPolarHBondContact O-CB 3.43Å; A107-L111 WeakPolarHBondContact O-CG 3.45Å; A107-L111 PolarHBondContact O-N 2.85Å; A107-F162 HydrophobicContact CB-CE1 3.85Å; A107-F162 HydrophobicContact CB-CZ 3.91Å
108	V	84.4	Confident	87.6	Confident	5 Å²	5	29 Å²	29	3%	0.03	17%	0.166	C	C	.	.	H	α-helix	trans	-66.8	-38.2	177.7	-175.1	0	0	0	0	111.8	E104 A105 T106 I110 L111 I112 L155 L165 F289	E104-V108 WeakPolarHBondContact O-CG2 3.38Å; E104-V108 PolarHBondContact O-N 3.39Å; A105-V108 PolarHBondContact O-N 2.88Å; T106-V108 VanDerWaalsContact C-N 3.33Å; T106-V108 PolarHBondContact O-N 3.34Å; V108-I110 VanDerWaalsContact C-N 3.35Å; V108-I110 PolarHBondContact O-N 2.84Å; V108-L111 PolarHBondContact O-N 3.28Å; V108-I112 HydrophobicContact CG1-CD1 4.18Å; V108-I112 HydrophobicContact CG1-CG1 4.46Å; V108-I112 VanDerWaalsContact O-CG1 3.29Å; V108-I112 WeakPolarHBondContact O-CG1 3.26Å; V108-I112 PolarHBondContact O-N 2.83Å; V108-L155 HydrophobicContact CG1-CD2 4.33Å; V108-L165 HydrophobicContact CG2-CD1 4.36Å; V108-L165 HydrophobicContact CG2-CD2 4.4Å; V108-F289 HydrophobicContact CB-CZ 4.04Å; V108-F289 HydrophobicContact CG1-CE2 4.04Å; V108-F289 HydrophobicContact CG1-CZ 3.49Å; V108-F289 VanDerWaalsContact CG1-CZ 3.49Å
109	V	87.6	Confident	87.1	Confident	0 Å²	0	25 Å²	25	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-61.5	-43.1	174.9	171.2	0	0	0	0	111.7	A105 T106 I112 C113 V285 I294 M297 F300	A105-V109 WeakPolarHBondContact O-CG2 3.49Å; A105-V109 PolarHBondContact O-N 2.72Å; T106-V109 PolarHBondContact O-N 2.95Å; V109-I112 WeakPolarHBondContact O-CB 3.49Å; V109-I112 PolarHBondContact O-N 3.09Å; V109-C113 PolarHBondContact O-N 2.69Å; V109-V285 HydrophobicContact CG1-CG1 4.28Å; V109-V285 HydrophobicContact CG1-CG2 3.9Å; V109-V285 HydrophobicContact CG2-CG1 4.02Å; V109-V285 HydrophobicContact CG2-CG2 4.42Å; V109-I294 HydrophobicContact CG2-CG2 3.96Å; V109-M297 HydrophobicContact CB-CE 3.94Å; V109-M297 HydrophobicContact CG1-CB 4.32Å; V109-M297 HydrophobicContact CG1-CE 3.76Å; V109-M297 HydrophobicContact CG2-CB 4.09Å; V109-F300 HydrophobicContact CG1-CB 4.27Å; V109-F300 HydrophobicContact CG1-CD1 4.32Å
110	I	91.9	Very high	86.4	Confident	0 Å²	0	25.4 Å²	25.4	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-68	-39.8	177.2	-69.2	159.9	0	0	0	111.2	A93 T97 L102 T106 A107 V108 I112 C113 G114 L237 I240 F300	A93-I110 HydrophobicContact CB-CG2 4.11Å; T97-I110 HydrophobicContact CG2-CB 3.61Å; T97-I110 HydrophobicContact CG2-CD1 3.9Å; T97-I110 HydrophobicContact CG2-CG1 4.38Å; T97-I110 HydrophobicContact CG2-CG2 3.5Å; T97-I110 VanDerWaalsContact CG2-CG2 3.5Å; L102-I110 HydrophobicContact CD1-CD1 3.2Å; T106-I110 HydrophobicContact CG2-CD1 3.96Å; T106-I110 PolarHBondContact O-N 3.47Å; T106-I110 VanDerWaalsContact O-N 3.08Å; A107-I110 PolarHBondContact O-N 3.29Å; V108-I110 VanDerWaalsContact C-N 3.35Å; V108-I110 PolarHBondContact O-N 2.84Å; I110-I112 VanDerWaalsContact C-N 3.32Å; I110-I112 PolarHBondContact O-N 3.18Å; I110-C113 PolarHBondContact O-N 3.04Å; I110-G114 PolarHBondContact O-N 2.8Å; I110-L237 HydrophobicContact CD1-CD2 4.05Å; I110-I240 HydrophobicContact CD1-CD1 3.93Å; I110-I240 HydrophobicContact CD1-CG2 4.18Å; I110-I240 HydrophobicContact CG1-CG2 4.38Å; I110-I240 HydrophobicContact CG2-CG2 3.87Å; I110-F300 HydrophobicContact CD1-CZ 4.4Å; I110-F300 HydrophobicContact CG1-CD1 4.17Å; I110-F300 HydrophobicContact CG1-CE1 3.64Å; I110-F300 HydrophobicContact CG1-CE2 4.42Å; I110-F300 HydrophobicContact CG1-CZ 3.79Å
111	L	90.4	Very high	86.1	Confident	0 Å²	0	24.7 Å²	24.7	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-60.4	-40.8	173.3	-79.5	167.3	0	0	0	112	A93 F94 A107 V108 C113 G114 C115 Y158 F162	A93-L111 HydrophobicContact CB-CD2 4.17Å; F94-L111 HydrophobicContact CB-CD2 3.95Å; A107-L111 WeakPolarHBondContact O-CB 3.43Å; A107-L111 WeakPolarHBondContact O-CG 3.45Å; A107-L111 PolarHBondContact O-N 2.85Å; V108-L111 PolarHBondContact O-N 3.28Å; L111-C113 VanDerWaalsContact C-N 3.32Å; L111-C113 PolarHBondContact O-N 3.22Å; L111-G114 PolarHBondContact O-N 2.97Å; L111-C115 WeakPolarHBondContact O-CB 3.42Å; L111-C115 PolarHBondContact O-N 3.35Å; L111-C115 PolarHBondContact O-SG 2.74Å; L111-Y158 HydrophobicContact CD2-CG 4.14Å; L111-F162 HydrophobicContact CD1-CE2 3.78Å; L111-F162 HydrophobicContact CD1-CZ 4.28Å
112	I	87.9	Confident	86.1	Confident	0 Å²	0	16.3 Å²	16.3	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-57.2	-47.6	174.2	-74	166.3	0	0	0	110.4	V108 V109 I110 G114 C115 C116 M151 L155 V284 V285 F289	V108-I112 HydrophobicContact CG1-CD1 4.18Å; V108-I112 HydrophobicContact CG1-CG1 4.46Å; V108-I112 VanDerWaalsContact O-CG1 3.29Å; V108-I112 WeakPolarHBondContact O-CG1 3.26Å; V108-I112 PolarHBondContact O-N 2.83Å; V109-I112 WeakPolarHBondContact O-CB 3.49Å; V109-I112 PolarHBondContact O-N 3.09Å; I110-I112 VanDerWaalsContact C-N 3.32Å; I110-I112 PolarHBondContact O-N 3.18Å; I112-G114 VanDerWaalsContact C-N 3.33Å; I112-G114 PolarHBondContact O-N 2.77Å; I112-C115 PolarHBondContact O-N 3.4Å; I112-C116 PolarHBondContact O-N 3.44Å; I112-C116 PolarHBondContact O-SG 3.26Å; I112-M151 HydrophobicContact CB-CE 4.42Å; I112-M151 HydrophobicContact CG2-CE 3.58Å; I112-M151 WeakPolarHBondContact O-CE 3.12Å; I112-L155 HydrophobicContact CD1-CD2 4.24Å; I112-L155 HydrophobicContact CG1-CD1 4.24Å; I112-L155 HydrophobicContact CG1-CD2 3.65Å; I112-L155 HydrophobicContact CG1-CG 4.34Å; I112-V284 HydrophobicContact CD1-CG1 4.22Å; I112-V284 HydrophobicContact CG1-CG1 4.38Å; I112-V284 HydrophobicContact CG2-CB 3.94Å; I112-V284 HydrophobicContact CG2-CG1 3.77Å; I112-V285 HydrophobicContact CB-CG2 4.27Å; I112-V285 HydrophobicContact CD1-CG2 4.17Å; I112-V285 HydrophobicContact CG2-CG2 3.84Å; I112-F289 HydrophobicContact CD1-CD2 4.46Å; I112-F289 HydrophobicContact CD1-CE2 3.58Å; I112-F289 HydrophobicContact CD1-CZ 4.43Å
113	C	91.4	Very high	86.3	Confident	0 Å²	0	16.2 Å²	16.2	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-65.9	-35.1	178.3	-80.3	0	0	0	0	112.9	V109 I110 L111 C281 L304	V109-C113 PolarHBondContact O-N 2.69Å; I110-C113 PolarHBondContact O-N 3.04Å; L111-C113 VanDerWaalsContact C-N 3.32Å; L111-C113 PolarHBondContact O-N 3.22Å; C113-C281 WeakPolarHBondContact CA-SG 3.36Å; C113-C281 HydrophobicContact CB-CB 4.24Å; C113-C281 WeakPolarHBondContact CB-SG 3.27Å; C113-C281 PolarHBondContact N-SG 3.32Å; C113-C281 VanDerWaalsContact N-SG 3.41Å; C113-C281 WeakPolarHBondContact SG-CB 3.31Å; C113-C281 CovalentContact SG-SG 2.07Å; C113-C281 PolarHBondContact SG-SG 3.1Å; C113-L304 HydrophobicContact CB-CD2 3.63Å
114	G	92	Very high	86.5	Confident	0 Å²	0	18.1 Å²	18.1	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-71.2	-26.2	173.9	0	0	0	0	0	114.4	M89 P90 I110 L111 I112	M89-G114 CarbonylContact C-O 3.55Å; M89-G114 VanDerWaalsContact CB-O 3.25Å; M89-G114 WeakPolarHBondContact CB-O 3.32Å; P90-G114 WeakPolarHBondContact CD-O 3.22Å; I110-G114 PolarHBondContact O-N 2.8Å; L111-G114 PolarHBondContact O-N 2.97Å; I112-G114 VanDerWaalsContact C-N 3.33Å; I112-G114 PolarHBondContact O-N 2.77Å
115	C	89.6	Confident	87	Confident	0 Å²	0	17 Å²	17	0%	0	11%	0.106	C	C	.	.	T	Hydrogen-bonded Turn	trans	-90	-0.4	178.3	-62.4	0	0	0	0	113.7	L111 I112 M151 L155	L111-C115 WeakPolarHBondContact O-CB 3.42Å; L111-C115 PolarHBondContact O-N 3.35Å; L111-C115 PolarHBondContact O-SG 2.74Å; I112-C115 PolarHBondContact O-N 3.4Å; C115-M151 HydrophobicContact CB-CB 4.5Å; C115-M151 HydrophobicContact CB-CG 3.87Å; C115-L155 HydrophobicContact CB-CD1 3.84Å
116	C	87.4	Confident	87.5	Confident	0 Å²	0	15.3 Å²	15.3	0%	0	9%	0.092	C	C	.	.	P	Polyproline II helix	trans	-66.8	152.3	175	-74.9	0	0	0	0	110.8	Q85 I112 Q276 L280 C281	Q85-C116 PolarHBondContact NE2-O 2.84Å; I112-C116 PolarHBondContact O-N 3.44Å; I112-C116 PolarHBondContact O-SG 3.26Å; C116-Q276 PolarHBondContact O-OE1 3.27Å; C116-L280 HydrophobicContact CB-CD2 4.41Å; C116-C281 VanDerWaalsContact SG-CA 3.55Å; C116-C281 VanDerWaalsContact SG-CB 3.54Å
117	P	87.6	Confident	87.8	Confident	1 Å²	1	19.7 Å²	19.7	1%	0.006	11%	0.114	C	C	.	.	P	Polyproline II helix	trans	-73.7	172.2	166.9	33.4	-30.7	0	0	0	110.7	A147 Q276 N277 L280	P117-A147 HydrophobicContact CB-CB 4.16Å; P117-A147 HydrophobicContact CG-CB 3.86Å; P117-Q276 PolarHBondContact O-OE1 3.22Å; P117-N277 HydrophobicContact CG-CB 4.38Å; P117-N277 WeakPolarHBondContact O-CB 3.5Å; P117-N277 PolarHBondContact O-N 3.22Å; P117-L280 HydrophobicContact CG-CD2 3.67Å
118	G	84.5	Confident	88	Confident	0 Å²	0	21 Å²	21	0%	0	12%	0.124	C	C	.	.	B	Isolated β-bridge	trans	-56.2	145.9	171.3	0	0	0	0	0	111.6	S143 C275	G118-S143 PolarHBondContact N-OG 2.69Å; G118-C275 WeakPolarHBondContact CA-O 3.32Å
119	G	79.4	Confident	88.4	Confident	3 Å²	3	21.3 Å²	21.3	3%	0.031	13%	0.126	C	C	.	.	P	Polyproline II helix	trans	-96	152.4	179.4	0	0	0	0	0	112.6	L121 S122 C275	G119-L121 PolarHBondContact O-N 3.47Å; G119-S122 VanDerWaalsContact O-CB 3.28Å; G119-S122 WeakPolarHBondContact O-CB 3.37Å; G119-S122 PolarHBondContact O-N 2.83Å; G119-S122 PolarHBondContact O-OG 2.85Å; G119-C275 PolarHBondContact N-O 3.38Å
120	A	77.1	Confident	88.6	Confident	71 Å²	71	27 Å²	27	59%	0.587	15%	0.151	S	C	*	.	T	Hydrogen-bonded Turn	trans	-56.3	-20.8	177.8	0	0	0	0	0	114.5	S122 N123	A120-S122 VanDerWaalsContact C-N 3.27Å; A120-S122 PolarHBondContact O-N 3.06Å; A120-N123 WeakPolarHBondContact O-CB 3.31Å; A120-N123 PolarHBondContact O-N 2.94Å
121	L	84.8	Confident	88.5	Confident	65 Å²	65	27.7 Å²	27.7	34%	0.34	16%	0.158	S	C	.	.	H	α-helix	trans	-62.1	-32.9	172.5	-179.6	67.2	0	0	0	112.2	G119 N123 I124 L125 V309	G119-L121 PolarHBondContact O-N 3.47Å; L121-N123 PolarHBondContact O-N 2.66Å; L121-I124 PolarHBondContact O-N 2.88Å; L121-I124 VanDerWaalsContact O-N 3.09Å; L121-L125 HydrophobicContact CD2-CD1 4.29Å; L121-L125 HydrophobicContact CG-CD1 3.97Å; L121-L125 HydrophobicContact CG-CG 4.16Å; L121-L125 WeakPolarHBondContact O-CG 3.39Å; L121-L125 PolarHBondContact O-N 3.35Å; L121-V309 HydrophobicContact CD2-CG2 3.63Å
122	S	87.4	Confident	88.5	Confident	0 Å²	0	29.5 Å²	29.5	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-56.4	-38.2	178.9	67.6	0	0	0	0	112	G119 A120 I124 L125 A126 T140 E272 C275	G119-S122 VanDerWaalsContact O-CB 3.28Å; G119-S122 WeakPolarHBondContact O-CB 3.37Å; G119-S122 PolarHBondContact O-N 2.83Å; G119-S122 PolarHBondContact O-OG 2.85Å; A120-S122 VanDerWaalsContact C-N 3.27Å; A120-S122 PolarHBondContact O-N 3.06Å; S122-I124 VanDerWaalsContact C-N 3.35Å; S122-I124 PolarHBondContact O-N 3.13Å; S122-L125 PolarHBondContact O-N 3.3Å; S122-A126 VanDerWaalsContact O-CB 3.31Å; S122-A126 WeakPolarHBondContact O-CB 3.42Å; S122-A126 PolarHBondContact O-N 3.44Å; S122-T140 PolarHBondContact OG-OG1 2.88Å; S122-E272 WeakPolarHBondContact CB-OE2 3.45Å; S122-E272 PolarHBondContact OG-OE2 3.46Å; S122-C275 PolarHBondContact N-SG 3.11Å; S122-C275 VanDerWaalsContact N-SG 3.37Å
123	N	88.9	Confident	88.4	Confident	29 Å²	29	31.8 Å²	31.8	16%	0.155	18%	0.179	C	C	.	.	H	α-helix	trans	-57.7	-47.4	176.9	-64.6	-36	0	0	0	111.3	A120 L121 A126 L127 M133 S136 I137	A120-N123 WeakPolarHBondContact O-CB 3.31Å; A120-N123 PolarHBondContact O-N 2.94Å; L121-N123 PolarHBondContact O-N 2.66Å; N123-A126 PolarHBondContact O-N 2.94Å; N123-L127 PolarHBondContact O-N 3.32Å; N123-M133 HydrophobicContact CB-SD 3.79Å; N123-M133 WeakPolarHBondContact O-CE 3.39Å; N123-S136 VanDerWaalsContact OD1-C 3.26Å; N123-S136 VanDerWaalsContact OD1-CB 3.22Å; N123-S136 WeakPolarHBondContact OD1-CB 3.2Å; N123-S136 PolarHBondContact OD1-OG 2.95Å; N123-S136 VanDerWaalsContact OD1-OG 3.11Å; N123-I137 PolarHBondContact OD1-N 2.91Å
124	I	89.9	Confident	88	Confident	112 Å²	112	36.4 Å²	36.4	57%	0.574	20%	0.204	S	C	*	.	H	α-helix	trans	-65.7	-41.5	179.2	-57.7	174.7	0	0	0	110.3	L121 S122 L127 A128	L121-I124 PolarHBondContact O-N 2.88Å; L121-I124 VanDerWaalsContact O-N 3.09Å; S122-I124 VanDerWaalsContact C-N 3.35Å; S122-I124 PolarHBondContact O-N 3.13Å; I124-L127 WeakPolarHBondContact O-CB 3.47Å; I124-L127 PolarHBondContact O-N 3.39Å; I124-A128 WeakPolarHBondContact O-CB 3.43Å; I124-A128 PolarHBondContact O-N 2.91Å
125	L	91.4	Very high	87.7	Confident	16 Å²	16	37 Å²	37	8%	0.084	21%	0.207	C	C	.	.	H	α-helix	trans	-66.4	-40.4	178.4	-61.4	174.5	0	0	0	112	L121 S122 L127 A128 I129 M271 C275 A312 I316	L121-L125 HydrophobicContact CD2-CD1 4.29Å; L121-L125 HydrophobicContact CG-CD1 3.97Å; L121-L125 HydrophobicContact CG-CG 4.16Å; L121-L125 WeakPolarHBondContact O-CG 3.39Å; L121-L125 PolarHBondContact O-N 3.35Å; S122-L125 PolarHBondContact O-N 3.3Å; L125-L127 VanDerWaalsContact C-N 3.32Å; L125-L127 PolarHBondContact O-N 3.36Å; L125-A128 PolarHBondContact O-N 3.47Å; L125-I129 PolarHBondContact O-N 3.43Å; L125-I129 VanDerWaalsContact O-N 3.08Å; L125-M271 HydrophobicContact CB-CB 4.36Å; L125-M271 HydrophobicContact CB-CG 4.22Å; L125-M271 HydrophobicContact CB-SD 3.92Å; L125-C275 HydrophobicContact CD1-CB 4.27Å; L125-A312 HydrophobicContact CD1-CB 3.55Å; L125-A312 HydrophobicContact CD2-CB 3.79Å; L125-A312 HydrophobicContact CG-CB 4.23Å; L125-I316 HydrophobicContact CD2-CD1 3.73Å
126	A	91.1	Very high	87.6	Confident	0 Å²	0	37 Å²	37	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-59.7	-43.1	173.3	0	0	0	0	0	110.6	S122 N123 A128 K130 G131 T268	S122-A126 VanDerWaalsContact O-CB 3.31Å; S122-A126 WeakPolarHBondContact O-CB 3.42Å; S122-A126 PolarHBondContact O-N 3.44Å; N123-A126 PolarHBondContact O-N 2.94Å; A126-A128 PolarHBondContact O-N 3.45Å; A126-K130 PolarHBondContact O-N 2.85Å; A126-G131 WeakPolarHBondContact O-CA 3.29Å; A126-G131 PolarHBondContact O-N 3.38Å; A126-T268 HydrophobicContact CB-CG2 4.34Å
127	L	91.1	Very high	87.4	Confident	111 Å²	111	38.7 Å²	38.7	58%	0.581	22%	0.216	S	C	*	.	H	α-helix	trans	-59.3	-48.3	172.7	-162.5	55.6	0	0	0	112	N123 I124 L125 I129 K130 M133	N123-L127 PolarHBondContact O-N 3.32Å; I124-L127 WeakPolarHBondContact O-CB 3.47Å; I124-L127 PolarHBondContact O-N 3.39Å; L125-L127 VanDerWaalsContact C-N 3.32Å; L125-L127 PolarHBondContact O-N 3.36Å; L127-I129 PolarHBondContact O-N 2.94Å; L127-K130 PolarHBondContact O-N 3.43Å; L127-M133 HydrophobicContact CB-CE 3.43Å; L127-M133 VanDerWaalsContact CB-CE 3.43Å; L127-M133 HydrophobicContact CD1-CE 3.85Å; L127-M133 HydrophobicContact CD2-CE 3.97Å; L127-M133 HydrophobicContact CG-CE 3.93Å
128	A	91.4	Very high	87.1	Confident	27 Å²	27	39.1 Å²	39.1	22%	0.223	22%	0.218	C	C	.	.	H	α-helix	trans	-63.1	-31.1	-173	0	0	0	0	0	112.6	I124 L125 A126 I316	I124-A128 WeakPolarHBondContact O-CB 3.43Å; I124-A128 PolarHBondContact O-N 2.91Å; L125-A128 PolarHBondContact O-N 3.47Å; A126-A128 PolarHBondContact O-N 3.45Å; A128-I316 HydrophobicContact CB-CD1 3.65Å; A128-I316 HydrophobicContact CB-CG1 4.14Å; A128-I316 HydrophobicContact CB-CG2 4.26Å
129	I	93.6	Very high	87.2	Confident	13 Å²	13	39.1 Å²	39.1	7%	0.067	22%	0.218	C	C	.	.	T	Hydrogen-bonded Turn	trans	-93.6	13.8	176	-151.5	170.4	0	0	0	113.2	L125 L127 G131 R267 M271 I316 F319	L125-I129 PolarHBondContact O-N 3.43Å; L125-I129 VanDerWaalsContact O-N 3.08Å; L127-I129 PolarHBondContact O-N 2.94Å; I129-G131 VanDerWaalsContact C-N 3.3Å; I129-G131 PolarHBondContact O-N 3.5Å; I129-R267 HydrophobicContact CG2-CB 3.88Å; I129-R267 PolarHBondContact O-NH1 3.44Å; I129-M271 HydrophobicContact CB-CE 4.33Å; I129-M271 HydrophobicContact CD1-CE 3.5Å; I129-M271 HydrophobicContact CG1-CE 4.48Å; I129-M271 HydrophobicContact CG2-CE 4.25Å; I129-M271 HydrophobicContact CG2-CG 4.15Å; I129-I316 HydrophobicContact CB-CG1 4.31Å; I129-F319 HydrophobicContact CB-CD1 4.4Å; I129-F319 HydrophobicContact CD1-CB 3.89Å; I129-F319 HydrophobicContact CD1-CG 4.12Å; I129-F319 HydrophobicContact CG1-CB 3.67Å; I129-F319 HydrophobicContact CG1-CD1 3.53Å; I129-F319 HydrophobicContact CG1-CD2 4.07Å; I129-F319 HydrophobicContact CG1-CE1 4.24Å; I129-F319 HydrophobicContact CG1-CG 3.44Å; I129-F319 VanDerWaalsContact CG1-CG 3.44Å; I129-F319 WeakPolarHBondContact O-CE1 3.33Å
130	K	91.9	Very high	87.4	Confident	118 Å²	118	39.6 Å²	39.6	51%	0.513	22%	0.221	S	C	.	.	T	Hydrogen-bonded Turn	trans	56.3	37.6	-177	-55.8	-176.9	179.7	-175.5	0	113.7	A126 L127 R267 F319 H323	A126-K130 PolarHBondContact O-N 2.85Å; L127-K130 PolarHBondContact O-N 3.43Å; K130-R267 PolarHBondContact O-NH1 3.03Å; K130-R267 PolarHBondContact O-NH2 3.2Å; K130-F319 HydrophobicContact CB-CE1 4.32Å; K130-F319 HydrophobicContact CB-CZ 4.36Å; K130-F319 HydrophobicContact CD-CE1 4.22Å; K130-F319 HydrophobicContact CD-CZ 4.28Å; K130-F319 HydrophobicContact CG-CE1 4.11Å; K130-F319 HydrophobicContact CG-CZ 4.45Å; K130-H323 PolarHBondContact NZ-CE1 2.87Å; K130-H323 VanDerWaalsContact NZ-CE1 3.32Å; K130-H323 PolarHBondContact NZ-NE2 2.72Å
131	G	90.6	Very high	87.5	Confident	16 Å²	16	36.8 Å²	36.8	17%	0.165	20%	0.196	C	C	.	.			trans	-76.8	179.9	172.4	0	0	0	0	0	113.3	A126 I129 M133 P264	A126-G131 WeakPolarHBondContact O-CA 3.29Å; A126-G131 PolarHBondContact O-N 3.38Å; I129-G131 VanDerWaalsContact C-N 3.3Å; I129-G131 PolarHBondContact O-N 3.5Å; G131-M133 PolarHBondContact O-N 3.3Å; G131-P264 WeakPolarHBondContact CA-O 3.28Å
132	D	89.6	Confident	87.2	Confident	38 Å²	38	34.1 Å²	34.1	20%	0.203	18%	0.183	C	C	.	.			trans	-82	106.5	169.2	-172.1	-32.1	0	0	0	109.7	N134 L135 S136 P264 E265 T268	D132-N134 WeakPolarHBondContact OD1-CA 3.4Å; D132-N134 WeakPolarHBondContact OD1-CB 3.09Å; D132-N134 PolarHBondContact OD1-N 3.25Å; D132-L135 HydrophobicContact CB-CB 3.91Å; D132-L135 PolarHBondContact OD1-N 3.37Å; D132-S136 PolarHBondContact O-N 3.2Å; D132-P264 PolarHBondContact N-O 2.82Å; D132-E265 HydrophobicContact CB-CG 4.22Å; D132-T268 WeakPolarHBondContact CA-OG1 3.34Å; D132-T268 PolarHBondContact N-OG1 3.3Å; D132-T268 VanDerWaalsContact O-CG2 3.26Å; D132-T268 WeakPolarHBondContact O-CG2 3.41Å; D132-T268 PolarHBondContact O-OG1 3.42Å
133	M	85.6	Confident	87.1	Confident	48 Å²	48	34.2 Å²	34.2	24%	0.236	18%	0.184	C	C	.	.	H	α-helix	trans	-65.7	-38.5	177.9	176.5	63.6	71	0	0	112.3	N123 L127 G131 L135 S136 I137	N123-M133 HydrophobicContact CB-SD 3.79Å; N123-M133 WeakPolarHBondContact O-CE 3.39Å; L127-M133 HydrophobicContact CB-CE 3.43Å; L127-M133 VanDerWaalsContact CB-CE 3.43Å; L127-M133 HydrophobicContact CD1-CE 3.85Å; L127-M133 HydrophobicContact CD2-CE 3.97Å; L127-M133 HydrophobicContact CG-CE 3.93Å; G131-M133 PolarHBondContact O-N 3.3Å; M133-L135 VanDerWaalsContact C-N 3.28Å; M133-L135 PolarHBondContact O-N 3.45Å; M133-S136 WeakPolarHBondContact O-CB 3.38Å; M133-S136 PolarHBondContact O-N 3.46Å; M133-S136 VanDerWaalsContact O-N 3.14Å; M133-I137 HydrophobicContact CG-CD1 3.87Å; M133-I137 HydrophobicContact CG-CG1 4.41Å; M133-I137 WeakPolarHBondContact O-CG1 3.36Å; M133-I137 PolarHBondContact O-N 2.85Å; M133-I137 HydrophobicContact SD-CD1 4.1Å; M133-I137 HydrophobicContact SD-CG1 4.15Å
134	N	83.8	Confident	86.6	Confident	96 Å²	96	33.7 Å²	33.7	51%	0.513	18%	0.182	S	C	.	.	H	α-helix	trans	-64.3	-42.3	-178.9	-65.2	-23.8	0	0	0	109.1	D132 S136 V138	D132-N134 WeakPolarHBondContact OD1-CA 3.4Å; D132-N134 WeakPolarHBondContact OD1-CB 3.09Å; D132-N134 PolarHBondContact OD1-N 3.25Å; N134-S136 VanDerWaalsContact C-N 3.35Å; N134-S136 PolarHBondContact O-N 3.34Å; N134-V138 WeakPolarHBondContact O-CG2 3.28Å; N134-V138 PolarHBondContact O-N 2.82Å
135	L	85.3	Confident	85.9	Confident	13 Å²	13	30.7 Å²	30.7	7%	0.068	17%	0.167	C	C	.	.	H	α-helix	trans	-59.6	-44.8	173.2	-178.7	61.8	0	0	0	111.6	D132 M133 I137 V138 M139 L261 E265 T268 V269	D132-L135 HydrophobicContact CB-CB 3.91Å; D132-L135 PolarHBondContact OD1-N 3.37Å; M133-L135 VanDerWaalsContact C-N 3.28Å; M133-L135 PolarHBondContact O-N 3.45Å; L135-I137 PolarHBondContact O-N 3.32Å; L135-V138 PolarHBondContact O-N 3.21Å; L135-M139 HydrophobicContact CD1-CG 3.97Å; L135-M139 HydrophobicContact CD1-SD 4.11Å; L135-M139 HydrophobicContact CD2-SD 4.32Å; L135-M139 HydrophobicContact CG-CG 4.17Å; L135-M139 HydrophobicContact CG-SD 3.84Å; L135-M139 WeakPolarHBondContact O-CG 3.42Å; L135-M139 PolarHBondContact O-N 3.3Å; L135-L261 HydrophobicContact CD2-CD2 4.31Å; L135-E265 HydrophobicContact CD2-CB 3.7Å; L135-E265 HydrophobicContact CD2-CG 3.8Å; L135-T268 HydrophobicContact CB-CG2 4.09Å; L135-T268 HydrophobicContact CD2-CG2 4.23Å; L135-T268 HydrophobicContact CG-CG2 4.06Å; L135-V269 HydrophobicContact CD2-CG2 4.21Å
136	S	87.5	Confident	85.4	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-58.1	-51	-179.2	-151.1	0	0	0	0	111.4	N123 D132 M133 N134 V138 M139 T140 E272	N123-S136 VanDerWaalsContact OD1-C 3.26Å; N123-S136 VanDerWaalsContact OD1-CB 3.22Å; N123-S136 WeakPolarHBondContact OD1-CB 3.2Å; N123-S136 PolarHBondContact OD1-OG 2.95Å; N123-S136 VanDerWaalsContact OD1-OG 3.11Å; D132-S136 PolarHBondContact O-N 3.2Å; M133-S136 WeakPolarHBondContact O-CB 3.38Å; M133-S136 PolarHBondContact O-N 3.46Å; M133-S136 VanDerWaalsContact O-N 3.14Å; N134-S136 VanDerWaalsContact C-N 3.35Å; N134-S136 PolarHBondContact O-N 3.34Å; S136-V138 PolarHBondContact O-N 3.02Å; S136-M139 PolarHBondContact O-N 3.24Å; S136-M139 VanDerWaalsContact O-N 3.14Å; S136-T140 PolarHBondContact O-N 3.04Å; S136-T140 PolarHBondContact O-OG1 3Å; S136-E272 PolarHBondContact OG-OE2 2.95Å
137	I	82.8	Confident	84.8	Confident	35 Å²	35	33 Å²	33	18%	0.179	18%	0.18	C	C	.	.	H	α-helix	trans	-56.5	-41.9	-179.8	-68	168.5	0	0	0	110.6	K67 N123 M133 L135 T140 S141	K67-I137 HydrophobicContact CB-CG2 4.48Å; K67-I137 HydrophobicContact CD-CG2 3.76Å; N123-I137 PolarHBondContact OD1-N 2.91Å; M133-I137 HydrophobicContact CG-CD1 3.87Å; M133-I137 HydrophobicContact CG-CG1 4.41Å; M133-I137 WeakPolarHBondContact O-CG1 3.36Å; M133-I137 PolarHBondContact O-N 2.85Å; M133-I137 HydrophobicContact SD-CD1 4.1Å; M133-I137 HydrophobicContact SD-CG1 4.15Å; L135-I137 PolarHBondContact O-N 3.32Å; I137-T140 PolarHBondContact O-N 2.71Å; I137-S141 WeakPolarHBondContact O-CB 3.12Å; I137-S141 PolarHBondContact O-N 3.32Å; I137-S141 PolarHBondContact O-OG 3.36Å
138	V	81.9	Confident	84	Confident	10 Å²	10	29.7 Å²	29.7	6%	0.061	16%	0.163	C	C	.	.	H	α-helix	trans	-67.6	-46.4	-179.2	176.4	0	0	0	0	111.4	H71 V78 N134 L135 S136 T140 S141 C142	H71-V138 HydrophobicContact CB-CB 4.19Å; H71-V138 HydrophobicContact CB-CG1 3.98Å; H71-V138 HydrophobicContact CB-CG2 3.12Å; H71-V138 WeakPolarHBondContact CD2-CG2 3.39Å; V78-V138 HydrophobicContact CG2-CG1 3.95Å; N134-V138 WeakPolarHBondContact O-CG2 3.28Å; N134-V138 PolarHBondContact O-N 2.82Å; L135-V138 PolarHBondContact O-N 3.21Å; S136-V138 PolarHBondContact O-N 3.02Å; V138-T140 VanDerWaalsContact C-N 3.33Å; V138-T140 PolarHBondContact O-N 3.11Å; V138-S141 PolarHBondContact O-N 3.38Å; V138-C142 VanDerWaalsContact O-CB 3.23Å; V138-C142 WeakPolarHBondContact O-CB 3.19Å; V138-C142 PolarHBondContact O-N 3.03Å; V138-C142 PolarHBondContact O-SG 2.86Å; V138-C142 VanDerWaalsContact O-SG 3.35Å
139	M	85.4	Confident	83.3	Confident	0 Å²	0	31.5 Å²	31.5	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-61.5	-43.4	177.1	-63.6	-179.4	68.6	0	0	111.1	A81 L135 S136 S143 T268 V269 E272	A81-M139 VanDerWaalsContact CA-CE 3.47Å; A81-M139 HydrophobicContact CB-CB 3.79Å; A81-M139 HydrophobicContact CB-CE 3.37Å; A81-M139 HydrophobicContact CB-CG 3.63Å; A81-M139 HydrophobicContact CB-SD 4.29Å; L135-M139 HydrophobicContact CD1-CG 3.97Å; L135-M139 HydrophobicContact CD1-SD 4.11Å; L135-M139 HydrophobicContact CD2-SD 4.32Å; L135-M139 HydrophobicContact CG-CG 4.17Å; L135-M139 HydrophobicContact CG-SD 3.84Å; L135-M139 WeakPolarHBondContact O-CG 3.42Å; L135-M139 PolarHBondContact O-N 3.3Å; S136-M139 PolarHBondContact O-N 3.24Å; S136-M139 VanDerWaalsContact O-N 3.14Å; M139-S143 WeakPolarHBondContact O-CB 3.3Å; M139-S143 PolarHBondContact O-N 2.8Å; M139-S143 PolarHBondContact O-OG 3.12Å; M139-T268 HydrophobicContact SD-CG2 4.41Å; M139-V269 HydrophobicContact CE-CB 4.16Å; M139-V269 HydrophobicContact CE-CG1 3.98Å; M139-V269 HydrophobicContact CE-CG2 3.86Å; M139-V269 HydrophobicContact SD-CB 4.49Å; M139-V269 HydrophobicContact SD-CG2 3.81Å; M139-E272 HydrophobicContact CB-CG 3.65Å; M139-E272 HydrophobicContact CE-CB 3.96Å; M139-E272 HydrophobicContact CE-CG 3.83Å; M139-E272 HydrophobicContact SD-CB 4.22Å; M139-E272 HydrophobicContact SD-CG 4.15Å
140	T	84.2	Confident	82.8	Confident	14 Å²	14	33.1 Å²	33.1	9%	0.086	19%	0.186	C	C	.	.	H	α-helix	trans	-63.3	-49.8	177.3	-53.4	0	0	0	0	110.9	S122 S136 I137 V138 S143 T144 E272	S122-T140 PolarHBondContact OG-OG1 2.88Å; S136-T140 PolarHBondContact O-N 3.04Å; S136-T140 PolarHBondContact O-OG1 3Å; I137-T140 PolarHBondContact O-N 2.71Å; V138-T140 VanDerWaalsContact C-N 3.33Å; V138-T140 PolarHBondContact O-N 3.11Å; T140-S143 PolarHBondContact O-OG 2.89Å; T140-S143 VanDerWaalsContact O-OG 3.07Å; T140-T144 WeakPolarHBondContact O-CB 3.37Å; T140-T144 PolarHBondContact O-N 3.03Å; T140-T144 PolarHBondContact O-OG1 3.07Å; T140-E272 WeakPolarHBondContact CA-OE1 3.34Å; T140-E272 VanDerWaalsContact CB-OE1 3.29Å; T140-E272 WeakPolarHBondContact CB-OE1 3.23Å; T140-E272 PolarHBondContact N-OE1 3.29Å; T140-E272 VanDerWaalsContact OG1-CD 3.22Å; T140-E272 PolarHBondContact OG1-OE1 2.88Å; T140-E272 PolarHBondContact OG1-OE2 3.28Å; T140-E272 VanDerWaalsContact OG1-OE2 3.13Å
141	S	78.4	Confident	82.3	Confident	11 Å²	11	28 Å²	28	8%	0.077	16%	0.164	C	C	.	.	H	α-helix	trans	-64.7	-44.2	-178.6	-62.8	0	0	0	0	112.1	I137 V138 L145	I137-S141 WeakPolarHBondContact O-CB 3.12Å; I137-S141 PolarHBondContact O-N 3.32Å; I137-S141 PolarHBondContact O-OG 3.36Å; V138-S141 PolarHBondContact O-N 3.38Å; S141-L145 PolarHBondContact O-N 3.13Å
142	C	80.4	Confident	81.6	Confident	9 Å²	9	28.6 Å²	28.6	6%	0.061	16%	0.164	C	C	.	.	H	α-helix	trans	-65.6	-49.2	177.5	-73.5	0	0	0	0	111.6	V78 V138 T144 L145 L146	V78-C142 HydrophobicContact CG1-CB 4.3Å; V138-C142 VanDerWaalsContact O-CB 3.23Å; V138-C142 WeakPolarHBondContact O-CB 3.19Å; V138-C142 PolarHBondContact O-N 3.03Å; V138-C142 PolarHBondContact O-SG 2.86Å; V138-C142 VanDerWaalsContact O-SG 3.35Å; C142-T144 VanDerWaalsContact C-N 3.34Å; C142-T144 PolarHBondContact O-N 2.91Å; C142-L145 PolarHBondContact O-N 3.43Å; C142-L146 WeakPolarHBondContact O-CD1 3.41Å; C142-L146 PolarHBondContact O-N 3.01Å
143	S	84.1	Confident	81.2	Confident	2 Å²	2	31.5 Å²	31.5	1%	0.014	18%	0.18	C	C	.	.	H	α-helix	trans	-60.2	-47.1	178	60.4	0	0	0	0	110.5	Y86 G118 M139 T140 L145 L146 A147	Y86-S143 PolarHBondContact OH-O 3.07Å; G118-S143 PolarHBondContact N-OG 2.69Å; M139-S143 WeakPolarHBondContact O-CB 3.3Å; M139-S143 PolarHBondContact O-N 2.8Å; M139-S143 PolarHBondContact O-OG 3.12Å; T140-S143 PolarHBondContact O-OG 2.89Å; T140-S143 VanDerWaalsContact O-OG 3.07Å; S143-L145 VanDerWaalsContact C-N 3.34Å; S143-L145 PolarHBondContact O-N 3.46Å; S143-L146 CarbonylContact O-C 3.13Å; S143-L146 PolarHBondContact O-N 3.41Å; S143-A147 PolarHBondContact O-N 3.47Å
144	T	78.8	Confident	81.2	Confident	18 Å²	18	29.9 Å²	29.9	11%	0.11	17%	0.172	C	C	.	.	H	α-helix	trans	-54.7	-47.9	178.3	-62.6	0	0	0	0	111.4	M63 T140 C142 A147	M63-T144 HydrophobicContact CB-CG2 4.2Å; M63-T144 HydrophobicContact CE-CG2 3.28Å; M63-T144 WeakPolarHBondContact CE-O 3.34Å; M63-T144 HydrophobicContact CG-CG2 3.64Å; M63-T144 HydrophobicContact SD-CG2 4.19Å; T140-T144 WeakPolarHBondContact O-CB 3.37Å; T140-T144 PolarHBondContact O-N 3.03Å; T140-T144 PolarHBondContact O-OG1 3.07Å; C142-T144 VanDerWaalsContact C-N 3.34Å; C142-T144 PolarHBondContact O-N 2.91Å; T144-A147 WeakPolarHBondContact O-CB 3.42Å; T144-A147 PolarHBondContact O-N 2.85Å
145	L	76	Confident	81	Confident	49 Å²	49	25.6 Å²	25.6	26%	0.257	15%	0.149	S	C	.	.	H	α-helix	trans	-60.6	-46.6	173.7	-82.2	-161.2	0	0	0	113.7	M63 V65 I68 S141 C142 S143 A147 L148 I189	M63-L145 HydrophobicContact CE-CD2 4.22Å; V65-L145 HydrophobicContact CG2-CD2 4.18Å; I68-L145 HydrophobicContact CD1-CB 4.47Å; I68-L145 HydrophobicContact CD1-CD1 3.12Å; I68-L145 HydrophobicContact CD1-CD2 4.49Å; I68-L145 HydrophobicContact CD1-CG 3.46Å; I68-L145 VanDerWaalsContact CD1-CG 3.46Å; S141-L145 PolarHBondContact O-N 3.13Å; C142-L145 PolarHBondContact O-N 3.43Å; S143-L145 VanDerWaalsContact C-N 3.34Å; S143-L145 PolarHBondContact O-N 3.46Å; L145-A147 PolarHBondContact O-N 3.05Å; L145-L148 WeakPolarHBondContact O-CB 3.4Å; L145-L148 WeakPolarHBondContact O-CG 3.04Å; L145-L148 PolarHBondContact O-N 3.03Å; L145-I189 HydrophobicContact CD2-CD1 4.47Å
146	L	80.5	Confident	80.6	Confident	57 Å²	57	30.2 Å²	30.2	30%	0.298	17%	0.166	S	C	.	.	H	α-helix	trans	-64.5	-26.4	179.4	-90.7	84.1	0	0	0	112.1	I82 Y86 C142 S143 L148 A149 M150	I82-L146 HydrophobicContact CD1-CD2 3.68Å; I82-L146 HydrophobicContact CG1-CD2 3.84Å; I82-L146 HydrophobicContact CG2-CD2 4.2Å; Y86-L146 HydrophobicContact CD2-CB 4.48Å; Y86-L146 HydrophobicContact CE2-CB 3.77Å; C142-L146 WeakPolarHBondContact O-CD1 3.41Å; C142-L146 PolarHBondContact O-N 3.01Å; S143-L146 CarbonylContact O-C 3.13Å; S143-L146 PolarHBondContact O-N 3.41Å; L146-L148 PolarHBondContact O-N 3.23Å; L146-L148 VanDerWaalsContact O-N 3.11Å; L146-A149 PolarHBondContact O-N 3.15Å; L146-M150 HydrophobicContact CB-CG 4.12Å; L146-M150 HydrophobicContact CD2-CG 4.31Å; L146-M150 WeakPolarHBondContact O-CB 3.13Å; L146-M150 WeakPolarHBondContact O-CG 3.36Å; L146-M150 PolarHBondContact O-N 3.12Å
147	A	79	Confident	80.4	Confident	8 Å²	8	35.4 Å²	35.4	7%	0.066	19%	0.193	C	C	.	.	H	α-helix	trans	-53	-35.8	179.2	0	0	0	0	0	112.1	Y86 P117 S143 T144 L145 A149 M151 P152	Y86-A147 WeakPolarHBondContact OH-CA 3.34Å; Y86-A147 WeakPolarHBondContact OH-CB 3.44Å; Y86-A147 PolarHBondContact OH-N 2.6Å; Y86-A147 VanDerWaalsContact OH-N 3.12Å; P117-A147 HydrophobicContact CB-CB 4.16Å; P117-A147 HydrophobicContact CG-CB 3.86Å; S143-A147 PolarHBondContact O-N 3.47Å; T144-A147 WeakPolarHBondContact O-CB 3.42Å; T144-A147 PolarHBondContact O-N 2.85Å; L145-A147 PolarHBondContact O-N 3.05Å; A147-A149 PolarHBondContact O-N 3.27Å; A147-M151 WeakPolarHBondContact O-CB 3.47Å; A147-M151 PolarHBondContact O-N 2.87Å; A147-P152 WeakPolarHBondContact O-CD 3.43Å
148	L	73.7	Confident	80.3	Confident	41 Å²	41	35.4 Å²	35.4	22%	0.215	19%	0.191	C	C	.	.	H	α-helix	trans	-53.4	-39	177.9	-64.4	178.6	0	0	0	113.3	M63 L145 L146 P152 L182 C185 I189	M63-L148 HydrophobicContact CE-CD1 4.27Å; M63-L148 HydrophobicContact CE-CD2 4.07Å; M63-L148 HydrophobicContact CE-CG 3.98Å; M63-L148 HydrophobicContact SD-CD2 4.25Å; L145-L148 WeakPolarHBondContact O-CB 3.4Å; L145-L148 WeakPolarHBondContact O-CG 3.04Å; L145-L148 PolarHBondContact O-N 3.03Å; L146-L148 PolarHBondContact O-N 3.23Å; L146-L148 VanDerWaalsContact O-N 3.11Å; L148-P152 WeakPolarHBondContact O-CD 3.16Å; L148-P152 WeakPolarHBondContact O-CG 3.41Å; L148-L182 HydrophobicContact CB-CD1 3.59Å; L148-L182 HydrophobicContact CD2-CD1 3.94Å; L148-L182 HydrophobicContact CG-CD1 4.26Å; L148-L182 WeakPolarHBondContact O-CD1 3.28Å; L148-C185 HydrophobicContact CD2-CB 4.2Å; L148-C185 WeakPolarHBondContact CD2-SG 3.15Å; L148-I189 HydrophobicContact CD1-CD1 3.15Å; L148-I189 HydrophobicContact CD2-CD1 3.98Å; L148-I189 HydrophobicContact CG-CD1 4.07Å
149	A	76.4	Confident	80	Confident	66 Å²	66	35 Å²	35	55%	0.545	19%	0.188	S	C	.	.	H	α-helix	trans	-99.7	-44	179.1	0	0	0	0	0	111.7	L146 A147 P152 L153	L146-A149 PolarHBondContact O-N 3.15Å; A147-A149 PolarHBondContact O-N 3.27Å; A149-P152 WeakPolarHBondContact O-CD 3.21Å; A149-L153 VanDerWaalsContact O-CB 3.29Å; A149-L153 WeakPolarHBondContact O-CB 3.48Å; A149-L153 PolarHBondContact O-N 3.24Å
150	M	83	Confident	79.4	Confident	47 Å²	47	40.2 Å²	40.2	23%	0.232	21%	0.213	C	C	.	.	H	α-helix	trans	-70.8	-40.3	-173.2	-67.8	-60.8	-69.3	0	0	112.4	Y86 L146 L153 L154	Y86-M150 HydrophobicContact CD1-CB 3.64Å; Y86-M150 HydrophobicContact CD1-CG 4.42Å; Y86-M150 HydrophobicContact CD2-CB 4.14Å; Y86-M150 HydrophobicContact CD2-CG 4.08Å; Y86-M150 HydrophobicContact CE1-CB 3.74Å; Y86-M150 HydrophobicContact CE2-CB 4.22Å; Y86-M150 HydrophobicContact CE2-CG 4.32Å; Y86-M150 HydrophobicContact CG-CB 3.86Å; Y86-M150 HydrophobicContact CG-CE 4.13Å; Y86-M150 HydrophobicContact CG-CG 4.15Å; L146-M150 HydrophobicContact CB-CG 4.12Å; L146-M150 HydrophobicContact CD2-CG 4.31Å; L146-M150 WeakPolarHBondContact O-CB 3.13Å; L146-M150 WeakPolarHBondContact O-CG 3.36Å; L146-M150 PolarHBondContact O-N 3.12Å; M150-L153 PolarHBondContact O-N 3.46Å; M150-L153 HydrophobicContact SD-CD2 4.37Å; M150-L154 HydrophobicContact CB-CD1 4.32Å; M150-L154 HydrophobicContact CE-CD1 4.33Å; M150-L154 HydrophobicContact CE-CG 4.5Å; M150-L154 VanDerWaalsContact O-CB 3.28Å; M150-L154 WeakPolarHBondContact O-CB 3.09Å; M150-L154 WeakPolarHBondContact O-CD1 3.08Å; M150-L154 WeakPolarHBondContact O-CG 2.8Å; M150-L154 PolarHBondContact O-N 3.44Å
151	M	82.1	Confident	78.8	Confident	11 Å²	11	41.2 Å²	41.2	5%	0.054	23%	0.226	C	C	.	.	H	α-helix	trans	-63.2	-49.7	-178.5	-172.6	-177.4	-170.8	0	0	111	I112 C115 A147 L153 L155 L280 V284	I112-M151 HydrophobicContact CB-CE 4.42Å; I112-M151 HydrophobicContact CG2-CE 3.58Å; I112-M151 WeakPolarHBondContact O-CE 3.12Å; C115-M151 HydrophobicContact CB-CB 4.5Å; C115-M151 HydrophobicContact CB-CG 3.87Å; A147-M151 WeakPolarHBondContact O-CB 3.47Å; A147-M151 PolarHBondContact O-N 2.87Å; M151-L153 PolarHBondContact O-N 2.94Å; M151-L155 HydrophobicContact CG-CD1 3.84Å; M151-L155 WeakPolarHBondContact O-CB 3.39Å; M151-L155 WeakPolarHBondContact O-CD1 3.26Å; M151-L155 PolarHBondContact O-N 3.28Å; M151-L280 HydrophobicContact SD-CD2 4.07Å; M151-V284 HydrophobicContact CE-CB 4.06Å; M151-V284 HydrophobicContact CE-CG1 3.87Å; M151-V284 HydrophobicContact CE-CG2 3.92Å; M151-V284 HydrophobicContact SD-CG2 4.29Å
152	P	75.1	Confident	78.5	Confident	27 Å²	27	41.2 Å²	41.2	18%	0.175	23%	0.225	C	C	.	.	H	α-helix	trans	-56.9	-45.9	171.3	-27.9	35.2	0	0	0	114.9	A147 L148 A149 L155 Y156 L178	A147-P152 WeakPolarHBondContact O-CD 3.43Å; L148-P152 WeakPolarHBondContact O-CD 3.16Å; L148-P152 WeakPolarHBondContact O-CG 3.41Å; A149-P152 WeakPolarHBondContact O-CD 3.21Å; P152-L155 PolarHBondContact O-N 3.2Å; P152-Y156 WeakPolarHBondContact O-CB 3.28Å; P152-Y156 PolarHBondContact O-N 3.22Å; P152-L178 HydrophobicContact CB-CB 3.9Å; P152-L178 HydrophobicContact CB-CD1 3.93Å; P152-L178 HydrophobicContact CB-CD2 4.04Å; P152-L178 HydrophobicContact CB-CG 4.17Å; P152-L178 HydrophobicContact CG-CB 4.21Å; P152-L178 HydrophobicContact CG-CD2 4.03Å
153	L	80.6	Confident	77.6	Confident	100 Å²	100	45.2 Å²	45.2	52%	0.524	25%	0.252	S	S	.	.	H	α-helix	trans	-63	-45.4	-176.8	179.9	68.7	0	0	0	111.6	A149 M150 M151 Y156 L157	A149-L153 VanDerWaalsContact O-CB 3.29Å; A149-L153 WeakPolarHBondContact O-CB 3.48Å; A149-L153 PolarHBondContact O-N 3.24Å; M150-L153 PolarHBondContact O-N 3.46Å; M150-L153 HydrophobicContact SD-CD2 4.37Å; M151-L153 PolarHBondContact O-N 2.94Å; L153-Y156 WeakPolarHBondContact O-CB 3.06Å; L153-Y156 PolarHBondContact O-N 2.77Å; L153-L157 WeakPolarHBondContact O-CB 3.39Å; L153-L157 PolarHBondContact O-N 3.3Å
154	L	85.3	Confident	76.5	Confident	14 Å²	14	50.3 Å²	50.3	7%	0.073	28%	0.28	C	S	.	.	H	α-helix	trans	-69.9	-41.3	-180	-68.9	166.6	0	0	0	111.2	Y86 P90 M150 Y156 L157 Y158	Y86-L154 HydrophobicContact CD1-CD1 3.54Å; Y86-L154 HydrophobicContact CG-CD1 4.15Å; P90-L154 HydrophobicContact CB-CD1 4.34Å; P90-L154 HydrophobicContact CG-CD1 3.77Å; M150-L154 HydrophobicContact CB-CD1 4.32Å; M150-L154 HydrophobicContact CE-CD1 4.33Å; M150-L154 HydrophobicContact CE-CG 4.5Å; M150-L154 VanDerWaalsContact O-CB 3.28Å; M150-L154 WeakPolarHBondContact O-CB 3.09Å; M150-L154 WeakPolarHBondContact O-CD1 3.08Å; M150-L154 WeakPolarHBondContact O-CG 2.8Å; M150-L154 PolarHBondContact O-N 3.44Å; L154-Y156 VanDerWaalsContact C-N 3.3Å; L154-Y156 PolarHBondContact O-N 2.82Å; L154-L157 PolarHBondContact O-N 2.97Å; L154-Y158 HydrophobicContact CB-CD2 4.28Å; L154-Y158 HydrophobicContact CB-CE2 4.45Å; L154-Y158 HydrophobicContact CD2-CE2 4Å; L154-Y158 WeakPolarHBondContact O-CB 3.06Å; L154-Y158 WeakPolarHBondContact O-CD2 3.29Å; L154-Y158 PolarHBondContact O-N 3.11Å
155	L	80.6	Confident	75.3	Confident	5 Å²	5	49.7 Å²	49.7	3%	0.026	28%	0.275	C	S	.	.	H	α-helix	trans	-56.6	-47.7	172.1	-98.3	91.2	0	0	0	111	V108 I112 C115 M151 P152 L157 C159 L178	V108-L155 HydrophobicContact CG1-CD2 4.33Å; I112-L155 HydrophobicContact CD1-CD2 4.24Å; I112-L155 HydrophobicContact CG1-CD1 4.24Å; I112-L155 HydrophobicContact CG1-CD2 3.65Å; I112-L155 HydrophobicContact CG1-CG 4.34Å; C115-L155 HydrophobicContact CB-CD1 3.84Å; M151-L155 HydrophobicContact CG-CD1 3.84Å; M151-L155 WeakPolarHBondContact O-CB 3.39Å; M151-L155 WeakPolarHBondContact O-CD1 3.26Å; M151-L155 PolarHBondContact O-N 3.28Å; P152-L155 PolarHBondContact O-N 3.2Å; L155-L157 PolarHBondContact O-N 3Å; L155-C159 WeakPolarHBondContact O-CB 3.42Å; L155-C159 PolarHBondContact O-N 3.25Å; L155-C159 PolarHBondContact O-SG 2.79Å; L155-L178 HydrophobicContact CB-CD1 4.28Å
156	Y	76.8	Confident	74	Confident	110 Å²	110	52.9 Å²	52.9	43%	0.431	29%	0.289	S	S	.	.	H	α-helix	trans	-57.7	-47.4	177.1	172.9	-99.8	0	0	0	111.9	P152 L153 L154 H160 V175	P152-Y156 WeakPolarHBondContact O-CB 3.28Å; P152-Y156 PolarHBondContact O-N 3.22Å; L153-Y156 WeakPolarHBondContact O-CB 3.06Å; L153-Y156 PolarHBondContact O-N 2.77Å; L154-Y156 VanDerWaalsContact C-N 3.3Å; L154-Y156 PolarHBondContact O-N 2.82Å; Y156-H160 PolarHBondContact O-N 3.02Å; Y156-V175 HydrophobicContact CD2-CG2 3.57Å; Y156-V175 HydrophobicContact CE2-CG2 4.08Å; Y156-V175 HydrophobicContact CG-CG2 4.41Å
157	L	82.5	Confident	72.4	Confident	110 Å²	110	59.8 Å²	59.8	58%	0.576	32%	0.317	S	S	*	.	H	α-helix	trans	-64	-50.4	-178.7	-174.2	66.6	0	0	0	112.2	L153 L154 L155 H160	L153-L157 WeakPolarHBondContact O-CB 3.39Å; L153-L157 PolarHBondContact O-N 3.3Å; L154-L157 PolarHBondContact O-N 2.97Å; L155-L157 PolarHBondContact O-N 3Å; L157-H160 WeakPolarHBondContact O-CB 3.41Å; L157-H160 PolarHBondContact O-N 2.58Å
158	Y	82.4	Confident	70.9	Confident	35 Å²	35	62.8 Å²	62.8	14%	0.137	34%	0.341	C	S	.	.	H	α-helix	trans	-73.2	-30.7	-177.1	-75.7	-69.4	0	0	0	112.8	P90 L91 F94 L111 L154 H160 G161 F162	P90-Y158 HydrophobicContact CB-CD2 4.18Å; P90-Y158 HydrophobicContact CB-CE2 3.53Å; L91-Y158 WeakPolarHBondContact CA-OH 3.36Å; L91-Y158 WeakPolarHBondContact CB-OH 3.35Å; L91-Y158 HydrophobicContact CD1-CE1 4.26Å; L91-Y158 PolarHBondContact N-OH 3.43Å; F94-Y158 HydrophobicContact CB-CD1 3.49Å; F94-Y158 VanDerWaalsContact CB-CD1 3.49Å; F94-Y158 HydrophobicContact CB-CE1 3.65Å; F94-Y158 HydrophobicContact CB-CG 4.27Å; F94-Y158 HydrophobicContact CD1-CD1 4.02Å; F94-Y158 HydrophobicContact CD1-CE1 4.11Å; F94-Y158 AromaticContact CD2-CD1 3.47Å; F94-Y158 HydrophobicContact CD2-CD1 3.47Å; F94-Y158 VanDerWaalsContact CD2-CD1 3.47Å; F94-Y158 HydrophobicContact CD2-CE1 4.32Å; F94-Y158 HydrophobicContact CD2-CG 4.18Å; F94-Y158 HydrophobicContact CE2-CD1 4.14Å; F94-Y158 AromaticContact CG-CD1 3.37Å; F94-Y158 HydrophobicContact CG-CD1 3.37Å; F94-Y158 AromaticContact CG-CE1 3.78Å; F94-Y158 HydrophobicContact CG-CE1 3.78Å; F94-Y158 HydrophobicContact CG-CG 4.36Å; L111-Y158 HydrophobicContact CD2-CG 4.14Å; L154-Y158 HydrophobicContact CB-CD2 4.28Å; L154-Y158 HydrophobicContact CB-CE2 4.45Å; L154-Y158 HydrophobicContact CD2-CE2 4Å; L154-Y158 WeakPolarHBondContact O-CB 3.06Å; L154-Y158 WeakPolarHBondContact O-CD2 3.29Å; L154-Y158 PolarHBondContact O-N 3.11Å; Y158-H160 PolarHBondContact O-N 3.41Å; Y158-G161 PolarHBondContact O-N 2.97Å; Y158-F162 VanDerWaalsContact O-CD2 3.28Å; Y158-F162 WeakPolarHBondContact O-CD2 3.22Å; Y158-F162 WeakPolarHBondContact O-CE2 3.46Å
159	C	75.8	Confident	69.8	Low	0 Å²	0	62.9 Å²	62.9	0%	0	34%	0.344	C	S	.	.	H	α-helix	trans	-64.7	-24.7	172.7	-72.4	0	0	0	0	112.5	L155 G161 F162 L165 Y171	L155-C159 WeakPolarHBondContact O-CB 3.42Å; L155-C159 PolarHBondContact O-N 3.25Å; L155-C159 PolarHBondContact O-SG 2.79Å; C159-G161 PolarHBondContact O-N 3.42Å; C159-F162 PolarHBondContact O-N 3.05Å; C159-L165 HydrophobicContact CB-CD2 3.7Å; C159-Y171 HydrophobicContact CB-CE1 4.2Å; C159-Y171 PolarHBondContact O-OH 3.13Å
160	H	72.8	Confident	68.8	Low	111 Å²	111	64 Å²	64	51%	0.514	35%	0.346	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.2	-22.6	173.7	-153.8	77.9	0	0	0	112.6	Y156 L157 Y158 F162	Y156-H160 PolarHBondContact O-N 3.02Å; L157-H160 WeakPolarHBondContact O-CB 3.41Å; L157-H160 PolarHBondContact O-N 2.58Å; Y158-H160 PolarHBondContact O-N 3.41Å; H160-F162 PolarHBondContact O-N 2.88Å
161	G	70.9	Confident	67.4	Low	35 Å²	35	63.4 Å²	63.4	36%	0.361	34%	0.341	S	S	.	.	T	Hydrogen-bonded Turn	trans	-73	-3.3	175.3	0	0	0	0	0	114.6	K98 Y158 C159	K98-G161 VanDerWaalsContact CE-O 3.3Å; K98-G161 WeakPolarHBondContact CE-O 3.2Å; K98-G161 PolarHBondContact NZ-O 3.35Å; Y158-G161 PolarHBondContact O-N 2.97Å; C159-G161 PolarHBondContact O-N 3.42Å
162	F	72.7	Confident	66.2	Low	11 Å²	11	68.1 Å²	68.1	5%	0.048	37%	0.37	C	S	.	.			trans	-110.7	113.7	179.1	-61.9	-91.3	0	0	0	110.2	F94 K98 A107 L111 Y158 C159 H160 L165 Y171	F94-F162 AromaticContact CD2-CE2 3.8Å; F94-F162 HydrophobicContact CD2-CE2 3.8Å; F94-F162 AromaticContact CD2-CZ 4Å; F94-F162 HydrophobicContact CD2-CZ 4Å; F94-F162 HydrophobicContact CE2-CD2 4.34Å; F94-F162 AromaticContact CE2-CE2 3.6Å; F94-F162 HydrophobicContact CE2-CE2 3.6Å; F94-F162 AromaticContact CE2-CZ 3.91Å; F94-F162 HydrophobicContact CE2-CZ 3.91Å; K98-F162 HydrophobicContact CD-CE1 3.95Å; K98-F162 HydrophobicContact CD-CZ 4.38Å; K98-F162 HydrophobicContact CG-CE1 4.43Å; K98-F162 HydrophobicContact CG-CZ 4.44Å; A107-F162 HydrophobicContact CB-CE1 3.85Å; A107-F162 HydrophobicContact CB-CZ 3.91Å; L111-F162 HydrophobicContact CD1-CE2 3.78Å; L111-F162 HydrophobicContact CD1-CZ 4.28Å; Y158-F162 VanDerWaalsContact O-CD2 3.28Å; Y158-F162 WeakPolarHBondContact O-CD2 3.22Å; Y158-F162 WeakPolarHBondContact O-CE2 3.46Å; C159-F162 PolarHBondContact O-N 3.05Å; H160-F162 PolarHBondContact O-N 2.88Å; F162-L165 HydrophobicContact CB-CB 3.92Å; F162-Y171 PolarHBondContact O-OH 3.29Å
163	S	61.1	Low	65.4	Low	92 Å²	92	68.2 Å²	68.2	64%	0.643	38%	0.376	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.1	-25.4	-170.6	49.6	0	0	0	0	114.7
164	N	60.2	Low	64.4	Low	110 Å²	110	64.5 Å²	64.5	59%	0.588	36%	0.356	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87	-16.6	176.9	-51.8	-55.4	0	0	0	112.1	E104 Q166 K167 A168	E104-N164 VanDerWaalsContact OE1-CA 3.23Å; E104-N164 WeakPolarHBondContact OE1-CA 3.28Å; E104-N164 WeakPolarHBondContact OE1-CB 3.26Å; E104-N164 PolarHBondContact OE1-N 3.19Å; E104-N164 VanDerWaalsContact OE1-N 3.15Å; N164-Q166 PolarHBondContact O-N 2.97Å; N164-K167 PolarHBondContact O-N 3.46Å; N164-A168 PolarHBondContact O-N 3.4Å
165	L	54.8	Low	63.2	Low	4 Å²	4	66.6 Å²	66.6	2%	0.021	37%	0.369	C	S	.	.	H	α-helix	trans	-63.9	-29.7	177.9	-152.6	81.8	0	0	0	111.9	E104 V108 C159 F162 K167 A168 V169 I174	E104-L165 HydrophobicContact CB-CD1 3.59Å; E104-L165 HydrophobicContact CG-CD1 4.28Å; E104-L165 PolarHBondContact OE1-N 2.76Å; E104-L165 VanDerWaalsContact OE2-CA 3.28Å; E104-L165 WeakPolarHBondContact OE2-CA 3.01Å; E104-L165 PolarHBondContact OE2-N 3.49Å; V108-L165 HydrophobicContact CG2-CD1 4.36Å; V108-L165 HydrophobicContact CG2-CD2 4.4Å; C159-L165 HydrophobicContact CB-CD2 3.7Å; F162-L165 HydrophobicContact CB-CB 3.92Å; L165-K167 PolarHBondContact O-N 3.29Å; L165-A168 PolarHBondContact O-N 3.08Å; L165-V169 HydrophobicContact CD1-CG2 4.44Å; L165-V169 PolarHBondContact O-N 3.17Å; L165-V169 VanDerWaalsContact O-O 3.09Å; L165-I174 HydrophobicContact CD2-CD1 4.35Å
166	Q	47.7	Very low	62.4	Low	116 Å²	116	70.3 Å²	70.3	54%	0.542	39%	0.393	S	S	.	.	H	α-helix	trans	-58.7	-27.6	170.8	-85.6	-179.5	-8.1	0	0	114.8	N164 Y171	N164-Q166 PolarHBondContact O-N 2.97Å; Q166-Y171 HydrophobicContact CB-CE2 3.91Å; Q166-Y171 HydrophobicContact CG-CD2 3.91Å; Q166-Y171 HydrophobicContact CG-CE2 3.1Å
167	K	46.6	Very low	61.7	Low	202 Å²	202	67.6 Å²	67.6	88%	0.878	39%	0.39	S	S	*	.	H	α-helix	trans	-94.2	-24.6	176.8	-71.6	-178.3	177.6	178.4	0	112.8	N164 L165	N164-K167 PolarHBondContact O-N 3.46Å; L165-K167 PolarHBondContact O-N 3.29Å
168	A	47.7	Very low	60.8	Low	71 Å²	71	63 Å²	63	59%	0.587	37%	0.365	S	S	*	.	H	α-helix	trans	-99.3	-31	-172.7	0	0	0	0	0	114.6	N164 L165	N164-A168 PolarHBondContact O-N 3.4Å; L165-A168 PolarHBondContact O-N 3.08Å
169	V	50.8	Low	60.2	Low	43 Å²	43	65 Å²	65	26%	0.261	38%	0.382	S	S	.	.	S	Bend	trans	-138.1	113.1	-179.1	-171.6	0	0	0	0	109.6	L165 Y171 I174	L165-V169 HydrophobicContact CD1-CG2 4.44Å; L165-V169 PolarHBondContact O-N 3.17Å; L165-V169 VanDerWaalsContact O-O 3.09Å; V169-Y171 PolarHBondContact O-N 2.97Å; V169-Y171 VanDerWaalsContact O-N 3.1Å; V169-I174 HydrophobicContact CB-CD1 4.31Å; V169-I174 HydrophobicContact CG1-CD1 3.73Å; V169-I174 HydrophobicContact CG1-CG1 3.6Å
170	P	55.6	Low	59.8	Low	90 Å²	90	67.7 Å²	67.7	58%	0.584	40%	0.403	S	S	*	.			trans	-61.2	120.8	179.1	23.6	-30.9	0	0	0	109.1	V172 G173 I174	P170-V172 PolarHBondContact O-N 3.46Å; P170-V172 VanDerWaalsContact O-N 3.1Å; P170-G173 VanDerWaalsContact O-CA 3.29Å; P170-G173 WeakPolarHBondContact O-CA 3.15Å; P170-G173 PolarHBondContact O-N 2.94Å; P170-I174 PolarHBondContact O-N 3.44Å
171	Y	54.2	Low	59.6	Low	35 Å²	35	63.2 Å²	63.2	14%	0.137	38%	0.383	C	S	.	.	H	α-helix	trans	-53	-33.9	179.4	-76.1	-97.3	0	0	0	112.5	C159 F162 Q166 V169 G173 I174 V175	C159-Y171 HydrophobicContact CB-CE1 4.2Å; C159-Y171 PolarHBondContact O-OH 3.13Å; F162-Y171 PolarHBondContact O-OH 3.29Å; Q166-Y171 HydrophobicContact CB-CE2 3.91Å; Q166-Y171 HydrophobicContact CG-CD2 3.91Å; Q166-Y171 HydrophobicContact CG-CE2 3.1Å; V169-Y171 PolarHBondContact O-N 2.97Å; V169-Y171 VanDerWaalsContact O-N 3.1Å; Y171-G173 VanDerWaalsContact C-N 3.29Å; Y171-G173 PolarHBondContact O-N 2.88Å; Y171-I174 PolarHBondContact O-N 3.45Å; Y171-V175 WeakPolarHBondContact O-CG2 3.3Å; Y171-V175 PolarHBondContact O-N 3.26Å
172	V	56.4	Low	59.7	Low	109 Å²	109	64.5 Å²	64.5	66%	0.661	38%	0.381	S	S	*	.	H	α-helix	trans	-59.7	-40.6	172.8	-178.1	0	0	0	0	110.8	P170 V175 T176	P170-V172 PolarHBondContact O-N 3.46Å; P170-V172 VanDerWaalsContact O-N 3.1Å; V172-V175 PolarHBondContact O-N 3.38Å; V172-T176 VanDerWaalsContact O-CB 3.28Å; V172-T176 WeakPolarHBondContact O-CB 3.41Å; V172-T176 PolarHBondContact O-N 3.19Å; V172-T176 PolarHBondContact O-OG1 3.21Å
173	G	58.8	Low	60.1	Low	29 Å²	29	68.7 Å²	68.7	30%	0.299	41%	0.408	S	S	.	.	H	α-helix	trans	-63.4	-41.2	175.2	0	0	0	0	0	113.2	P170 Y171 T176 S177	P170-G173 VanDerWaalsContact O-CA 3.29Å; P170-G173 WeakPolarHBondContact O-CA 3.15Å; P170-G173 PolarHBondContact O-N 2.94Å; Y171-G173 VanDerWaalsContact C-N 3.29Å; Y171-G173 PolarHBondContact O-N 2.88Å; G173-T176 PolarHBondContact O-N 2.8Å; G173-S177 VanDerWaalsContact O-CB 3.26Å; G173-S177 WeakPolarHBondContact O-CB 3.32Å; G173-S177 PolarHBondContact O-N 3.43Å; G173-S177 PolarHBondContact O-OG 3.39Å
174	I	59.1	Low	61	Low	23 Å²	23	64.8 Å²	64.8	12%	0.118	38%	0.38	C	S	.	.	H	α-helix	trans	-64.6	-47.2	176.4	-61.9	174.4	0	0	0	110.6	L165 V169 P170 Y171 S177 L178	L165-I174 HydrophobicContact CD2-CD1 4.35Å; V169-I174 HydrophobicContact CB-CD1 4.31Å; V169-I174 HydrophobicContact CG1-CD1 3.73Å; V169-I174 HydrophobicContact CG1-CG1 3.6Å; P170-I174 PolarHBondContact O-N 3.44Å; Y171-I174 PolarHBondContact O-N 3.45Å; I174-S177 PolarHBondContact O-N 2.88Å; I174-L178 HydrophobicContact CG2-CD1 3.73Å; I174-L178 HydrophobicContact CG2-CG 4.46Å; I174-L178 WeakPolarHBondContact O-CB 3.34Å; I174-L178 WeakPolarHBondContact O-CD1 3.31Å; I174-L178 VanDerWaalsContact O-CG 3.24Å; I174-L178 WeakPolarHBondContact O-CG 2.9Å; I174-L178 PolarHBondContact O-N 3Å
175	V	59.9	Low	61.7	Low	57 Å²	57	59.8 Å²	59.8	35%	0.345	35%	0.354	S	S	.	.	H	α-helix	trans	-63.9	-42.5	178	175.7	0	0	0	0	111.1	Y156 Y171 V172 L178 V179	Y156-V175 HydrophobicContact CD2-CG2 3.57Å; Y156-V175 HydrophobicContact CE2-CG2 4.08Å; Y156-V175 HydrophobicContact CG-CG2 4.41Å; Y171-V175 WeakPolarHBondContact O-CG2 3.3Å; Y171-V175 PolarHBondContact O-N 3.26Å; V172-V175 PolarHBondContact O-N 3.38Å; V175-L178 PolarHBondContact O-N 3.29Å; V175-V179 WeakPolarHBondContact O-CG2 3.35Å; V175-V179 PolarHBondContact O-N 2.87Å
176	T	64.6	Low	62.8	Low	84 Å²	84	61 Å²	61	52%	0.515	37%	0.368	S	S	.	.	H	α-helix	trans	-66	-41.6	178.4	-47.7	0	0	0	0	111	V172 G173 V179 A180	V172-T176 VanDerWaalsContact O-CB 3.28Å; V172-T176 WeakPolarHBondContact O-CB 3.41Å; V172-T176 PolarHBondContact O-N 3.19Å; V172-T176 PolarHBondContact O-OG1 3.21Å; G173-T176 PolarHBondContact O-N 2.8Å; T176-V179 PolarHBondContact O-N 3.32Å; T176-A180 VanDerWaalsContact O-CB 3.26Å; T176-A180 WeakPolarHBondContact O-CB 3.21Å; T176-A180 PolarHBondContact O-N 3.4Å
177	S	61.6	Low	64.5	Low	52 Å²	52	57.6 Å²	57.6	36%	0.364	36%	0.359	S	S	.	.	H	α-helix	trans	-62.5	-41.9	173.4	-68.3	0	0	0	0	111.6	G173 I174 A180 I181	G173-S177 VanDerWaalsContact O-CB 3.26Å; G173-S177 WeakPolarHBondContact O-CB 3.32Å; G173-S177 PolarHBondContact O-N 3.43Å; G173-S177 PolarHBondContact O-OG 3.39Å; I174-S177 PolarHBondContact O-N 2.88Å; S177-A180 CarbonylContact O-C 3.41Å; S177-A180 PolarHBondContact O-N 3.49Å; S177-I181 WeakPolarHBondContact O-CD1 3.22Å; S177-I181 WeakPolarHBondContact O-CG1 3.14Å; S177-I181 PolarHBondContact O-N 2.9Å
178	L	64.1	Low	66.2	Low	13 Å²	13	48 Å²	48	7%	0.068	32%	0.317	C	S	.	.	H	α-helix	trans	-65.4	-40.3	176.8	-75.4	161.4	0	0	0	112.4	P152 L155 I174 V175 I181 L182	P152-L178 HydrophobicContact CB-CB 3.9Å; P152-L178 HydrophobicContact CB-CD1 3.93Å; P152-L178 HydrophobicContact CB-CD2 4.04Å; P152-L178 HydrophobicContact CB-CG 4.17Å; P152-L178 HydrophobicContact CG-CB 4.21Å; P152-L178 HydrophobicContact CG-CD2 4.03Å; L155-L178 HydrophobicContact CB-CD1 4.28Å; I174-L178 HydrophobicContact CG2-CD1 3.73Å; I174-L178 HydrophobicContact CG2-CG 4.46Å; I174-L178 WeakPolarHBondContact O-CB 3.34Å; I174-L178 WeakPolarHBondContact O-CD1 3.31Å; I174-L178 VanDerWaalsContact O-CG 3.24Å; I174-L178 WeakPolarHBondContact O-CG 2.9Å; I174-L178 PolarHBondContact O-N 3Å; V175-L178 PolarHBondContact O-N 3.29Å; L178-I181 WeakPolarHBondContact O-CB 3.08Å; L178-I181 PolarHBondContact O-N 2.91Å; L178-L182 WeakPolarHBondContact O-CB 3.42Å; L178-L182 PolarHBondContact O-N 3.28Å
179	V	68.2	Low	67.7	Low	79 Å²	79	45.6 Å²	45.6	48%	0.479	29%	0.294	S	S	.	.	H	α-helix	trans	-65.6	-41.3	172.8	172.6	0	0	0	0	110.7	V175 T176 I181 L182 V183	V175-V179 WeakPolarHBondContact O-CG2 3.35Å; V175-V179 PolarHBondContact O-N 2.87Å; T176-V179 PolarHBondContact O-N 3.32Å; V179-I181 PolarHBondContact O-N 3.33Å; V179-L182 WeakPolarHBondContact O-CB 3.43Å; V179-L182 PolarHBondContact O-N 2.9Å; V179-L182 VanDerWaalsContact O-N 3.09Å; V179-V183 WeakPolarHBondContact O-CG2 3.41Å; V179-V183 PolarHBondContact O-N 3.21Å; V179-V183 VanDerWaalsContact O-N 3.1Å
180	A	67.6	Low	69.2	Low	55 Å²	55	48.2 Å²	48.2	46%	0.455	31%	0.306	S	S	.	.	H	α-helix	trans	-64.2	-25.3	176	0	0	0	0	0	112.9	T176 S177 P184	T176-A180 VanDerWaalsContact O-CB 3.26Å; T176-A180 WeakPolarHBondContact O-CB 3.21Å; T176-A180 PolarHBondContact O-N 3.4Å; S177-A180 CarbonylContact O-C 3.41Å; S177-A180 PolarHBondContact O-N 3.49Å; A180-P184 WeakPolarHBondContact O-CD 3.38Å; A180-P184 WeakPolarHBondContact O-CG 3.1Å
181	I	70	Confident	70.6	Confident	17 Å²	17	46.6 Å²	46.6	9%	0.087	29%	0.292	C	S	.	.	H	α-helix	trans	-78.4	-40.5	171	-70.8	165.4	0	0	0	111.1	M56 S177 L178 V179 P184 C185 V287 A288	M56-I181 HydrophobicContact CE-CB 4.46Å; M56-I181 HydrophobicContact CE-CD1 4.48Å; M56-I181 HydrophobicContact CE-CG1 4.1Å; M56-I181 HydrophobicContact CE-CG2 3.69Å; M56-I181 HydrophobicContact CG-CG2 4.41Å; M56-I181 HydrophobicContact SD-CG2 3.65Å; S177-I181 WeakPolarHBondContact O-CD1 3.22Å; S177-I181 WeakPolarHBondContact O-CG1 3.14Å; S177-I181 PolarHBondContact O-N 2.9Å; L178-I181 WeakPolarHBondContact O-CB 3.08Å; L178-I181 PolarHBondContact O-N 2.91Å; V179-I181 PolarHBondContact O-N 3.33Å; I181-P184 WeakPolarHBondContact O-CD 3.36Å; I181-P184 WeakPolarHBondContact O-CG 3.34Å; I181-C185 VanDerWaalsContact O-CB 3.28Å; I181-C185 WeakPolarHBondContact O-CB 3.21Å; I181-C185 PolarHBondContact O-N 3.28Å; I181-V287 HydrophobicContact CD1-CG1 3.61Å; I181-V287 HydrophobicContact CG1-CG1 3.49Å; I181-V287 VanDerWaalsContact CG1-CG1 3.49Å; I181-A288 HydrophobicContact CD1-CB 4.46Å
182	L	71.7	Confident	72	Confident	62 Å²	62	46.1 Å²	46.1	33%	0.325	29%	0.292	S	S	.	.	H	α-helix	trans	-66	-41.3	-174.7	-175.9	57.9	0	0	0	112.9	L148 L178 V179 C185 G186	L148-L182 HydrophobicContact CB-CD1 3.59Å; L148-L182 HydrophobicContact CD2-CD1 3.94Å; L148-L182 HydrophobicContact CG-CD1 4.26Å; L148-L182 WeakPolarHBondContact O-CD1 3.28Å; L178-L182 WeakPolarHBondContact O-CB 3.42Å; L178-L182 PolarHBondContact O-N 3.28Å; V179-L182 WeakPolarHBondContact O-CB 3.43Å; V179-L182 PolarHBondContact O-N 2.9Å; V179-L182 VanDerWaalsContact O-N 3.09Å; L182-C185 PolarHBondContact O-N 2.85Å; L182-G186 PolarHBondContact O-N 2.58Å
183	V	80.7	Confident	73.2	Confident	100 Å²	100	47.1 Å²	47.1	61%	0.606	29%	0.285	S	S	*	.	H	α-helix	trans	-59.3	-56.9	-179.1	173.1	0	0	0	0	112.9	V179 C185 G186 A187	V179-V183 WeakPolarHBondContact O-CG2 3.41Å; V179-V183 PolarHBondContact O-N 3.21Å; V179-V183 VanDerWaalsContact O-N 3.1Å; V183-C185 VanDerWaalsContact C-N 3.3Å; V183-C185 PolarHBondContact O-N 3.46Å; V183-G186 PolarHBondContact O-N 2.84Å; V183-A187 PolarHBondContact O-N 3.45Å
184	P	79.9	Confident	74.5	Confident	10 Å²	10	51.4 Å²	51.4	7%	0.065	30%	0.296	C	S	.	.	H	α-helix	trans	-65.9	-32.7	177.7	24.4	-32.9	0	0	0	112.4	L53 M56 V57 A180 I181 A187 G188	L53-P184 HydrophobicContact CD2-CB 3.9Å; L53-P184 HydrophobicContact CD2-CG 4.02Å; M56-P184 HydrophobicContact CB-CB 3.82Å; M56-P184 HydrophobicContact CB-CG 3.65Å; M56-P184 HydrophobicContact CG-CG 4.31Å; V57-P184 WeakPolarHBondContact CA-O 3.34Å; V57-P184 HydrophobicContact CG2-CB 3.98Å; V57-P184 WeakPolarHBondContact CG2-O 3.19Å; A180-P184 WeakPolarHBondContact O-CD 3.38Å; A180-P184 WeakPolarHBondContact O-CG 3.1Å; I181-P184 WeakPolarHBondContact O-CD 3.36Å; I181-P184 WeakPolarHBondContact O-CG 3.34Å; P184-A187 PolarHBondContact O-N 3.4Å; P184-G188 PolarHBondContact O-N 2.71Å
185	C	75.7	Confident	75.8	Confident	5 Å²	5	57.9 Å²	57.9	3%	0.034	32%	0.318	C	S	.	.	H	α-helix	trans	-62.7	-48.7	173.9	-168.3	0	0	0	0	111.4	M56 G60 L148 I181 L182 V183 A187 G188 I189	M56-C185 WeakPolarHBondContact O-CA 3.45Å; G60-C185 WeakPolarHBondContact CA-O 3.39Å; L148-C185 HydrophobicContact CD2-CB 4.2Å; L148-C185 WeakPolarHBondContact CD2-SG 3.15Å; I181-C185 VanDerWaalsContact O-CB 3.28Å; I181-C185 WeakPolarHBondContact O-CB 3.21Å; I181-C185 PolarHBondContact O-N 3.28Å; L182-C185 PolarHBondContact O-N 2.85Å; V183-C185 VanDerWaalsContact C-N 3.3Å; V183-C185 PolarHBondContact O-N 3.46Å; C185-A187 VanDerWaalsContact C-N 3.29Å; C185-A187 PolarHBondContact O-N 2.83Å; C185-G188 WeakPolarHBondContact O-CA 3.32Å; C185-G188 PolarHBondContact O-N 3.26Å; C185-I189 WeakPolarHBondContact O-CG1 3.33Å; C185-I189 PolarHBondContact O-N 2.88Å
186	G	76.9	Confident	76.8	Confident	30 Å²	30	58.4 Å²	58.4	31%	0.309	32%	0.323	S	S	.	.	H	α-helix	trans	-58.4	-39	175.1	0	0	0	0	0	113.1	L182 V183 G188 I189 L190	L182-G186 PolarHBondContact O-N 2.58Å; V183-G186 PolarHBondContact O-N 2.84Å; G186-G188 PolarHBondContact O-N 3.37Å; G186-I189 WeakPolarHBondContact O-CB 3.5Å; G186-I189 PolarHBondContact O-N 3.28Å; G186-L190 PolarHBondContact O-N 2.93Å
187	A	84.1	Confident	77.7	Confident	44 Å²	44	61.8 Å²	61.8	36%	0.364	33%	0.333	S	S	.	.	H	α-helix	trans	-61.5	-42.2	172.8	0	0	0	0	0	112	V183 P184 C185 I189 L190 I191	V183-A187 PolarHBondContact O-N 3.45Å; P184-A187 PolarHBondContact O-N 3.4Å; C185-A187 VanDerWaalsContact C-N 3.29Å; C185-A187 PolarHBondContact O-N 2.83Å; A187-I189 VanDerWaalsContact C-N 3.34Å; A187-I189 PolarHBondContact O-N 3.04Å; A187-L190 WeakPolarHBondContact O-CB 3.35Å; A187-L190 PolarHBondContact O-N 3.05Å; A187-I191 VanDerWaalsContact O-CG1 3.3Å; A187-I191 WeakPolarHBondContact O-CG1 3.48Å; A187-I191 PolarHBondContact O-N 3.43Å
188	G	82.8	Confident	78.8	Confident	0 Å²	0	66 Å²	66	0%	0	34%	0.342	C	S	.	.	H	α-helix	trans	-59.4	-41.3	174.2	0	0	0	0	0	113.4	V57 C61 P184 C185 G186 L190 I191 N192	V57-G188 WeakPolarHBondContact O-CA 3.35Å; C61-G188 PolarHBondContact SG-O 3.28Å; P184-G188 PolarHBondContact O-N 2.71Å; C185-G188 WeakPolarHBondContact O-CA 3.32Å; C185-G188 PolarHBondContact O-N 3.26Å; G186-G188 PolarHBondContact O-N 3.37Å; G188-L190 VanDerWaalsContact C-N 3.34Å; G188-I191 PolarHBondContact O-N 2.66Å; G188-N192 PolarHBondContact O-N 3.23Å
189	I	78.4	Confident	79.6	Confident	20 Å²	20	65.5 Å²	65.5	10%	0.103	34%	0.34	C	S	.	.	H	α-helix	trans	-63.1	-44.1	175.8	-61.2	171.5	0	0	0	110.8	G60 M63 V65 L145 L148 C185 G186 A187 I191 N192 Y193	G60-I189 WeakPolarHBondContact O-CA 3.44Å; G60-I189 WeakPolarHBondContact O-CG1 3.47Å; G60-I189 PolarHBondContact O-N 3.44Å; M63-I189 HydrophobicContact CB-CG1 4.15Å; M63-I189 HydrophobicContact CE-CD1 4Å; M63-I189 HydrophobicContact CG-CG1 4.19Å; M63-I189 HydrophobicContact SD-CD1 3.25Å; M63-I189 WeakPolarHBondContact SD-CD1 3.44Å; M63-I189 HydrophobicContact SD-CG1 3.34Å; M63-I189 WeakPolarHBondContact SD-CG1 3.28Å; V65-I189 HydrophobicContact CG2-CG2 3.44Å; V65-I189 VanDerWaalsContact CG2-CG2 3.44Å; L145-I189 HydrophobicContact CD2-CD1 4.47Å; L148-I189 HydrophobicContact CD1-CD1 3.15Å; L148-I189 HydrophobicContact CD2-CD1 3.98Å; L148-I189 HydrophobicContact CG-CD1 4.07Å; C185-I189 WeakPolarHBondContact O-CG1 3.33Å; C185-I189 PolarHBondContact O-N 2.88Å; G186-I189 WeakPolarHBondContact O-CB 3.5Å; G186-I189 PolarHBondContact O-N 3.28Å; A187-I189 VanDerWaalsContact C-N 3.34Å; A187-I189 PolarHBondContact O-N 3.04Å; I189-I191 VanDerWaalsContact C-N 3.31Å; I189-I191 PolarHBondContact O-N 3.15Å; I189-N192 WeakPolarHBondContact O-CB 3.47Å; I189-N192 PolarHBondContact O-N 2.74Å; I189-N192 VanDerWaalsContact O-N 3.15Å; I189-Y193 WeakPolarHBondContact O-CB 3.25Å; I189-Y193 PolarHBondContact O-N 3.1Å
190	L	83.4	Confident	80.2	Confident	98 Å²	98	69.5 Å²	69.5	51%	0.513	35%	0.35	S	S	.	.	H	α-helix	trans	-62.8	-40.5	179.6	-160.1	63.8	0	0	0	111.4	G186 A187 G188 Y193 F194	G186-L190 PolarHBondContact O-N 2.93Å; A187-L190 WeakPolarHBondContact O-CB 3.35Å; A187-L190 PolarHBondContact O-N 3.05Å; G188-L190 VanDerWaalsContact C-N 3.34Å; L190-Y193 PolarHBondContact O-N 3.1Å; L190-F194 HydrophobicContact CD1-CD2 3.85Å; L190-F194 HydrophobicContact CD1-CE2 3.37Å; L190-F194 HydrophobicContact CD1-CZ 4.4Å; L190-F194 HydrophobicContact CD2-CE2 4.45Å; L190-F194 HydrophobicContact CG-CD2 3.81Å; L190-F194 HydrophobicContact CG-CE2 3.74Å; L190-F194 WeakPolarHBondContact O-CD2 3.44Å; L190-F194 PolarHBondContact O-N 2.87Å
191	I	85.4	Confident	81.1	Confident	56 Å²	56	72 Å²	72	29%	0.287	36%	0.355	S	S	.	.	H	α-helix	trans	-61.6	-45.4	172.7	-68.1	163.9	0	0	0	110.4	V57 A187 G188 I189 Y193 R195 I202	V57-I191 HydrophobicContact CG1-CD1 3.88Å; A187-I191 VanDerWaalsContact O-CG1 3.3Å; A187-I191 WeakPolarHBondContact O-CG1 3.48Å; A187-I191 PolarHBondContact O-N 3.43Å; G188-I191 PolarHBondContact O-N 2.66Å; I189-I191 VanDerWaalsContact C-N 3.31Å; I189-I191 PolarHBondContact O-N 3.15Å; I191-Y193 VanDerWaalsContact C-N 3.29Å; I191-Y193 PolarHBondContact O-N 3.01Å; I191-R195 CarbonylContact O-C 3.59Å; I191-R195 VanDerWaalsContact O-CA 3.28Å; I191-R195 WeakPolarHBondContact O-CA 3.39Å; I191-R195 PolarHBondContact O-N 3.29Å; I191-I202 HydrophobicContact CD1-CD1 4.36Å; I191-I202 HydrophobicContact CG2-CD1 3.92Å
192	N	83.7	Confident	81.8	Confident	26 Å²	26	73.3 Å²	73.3	14%	0.139	36%	0.362	C	S	.	.	H	α-helix	trans	-62.6	-37.8	177.6	-164.3	41.8	0	0	0	112.6	C61 M63 G188 I189 S199	C61-N192 PolarHBondContact O-ND2 3.3Å; C61-N192 PolarHBondContact O-OD1 3.27Å; M63-N192 PolarHBondContact O-ND2 3.32Å; G188-N192 PolarHBondContact O-N 3.23Å; I189-N192 WeakPolarHBondContact O-CB 3.47Å; I189-N192 PolarHBondContact O-N 2.74Å; I189-N192 VanDerWaalsContact O-N 3.15Å; N192-S199 WeakPolarHBondContact OD1-CB 3.48Å; N192-S199 PolarHBondContact OD1-OG 3.26Å
193	Y	80.6	Confident	82.2	Confident	129 Å²	129	71.7 Å²	71.7	51%	0.506	36%	0.355	S	S	.	.	H	α-helix	trans	-68.2	-49.8	179.9	-176.4	-101.3	0	0	0	112.5	V65 I189 L190 I191	V65-Y193 HydrophobicContact CB-CD2 4.2Å; V65-Y193 HydrophobicContact CG1-CD2 4.15Å; I189-Y193 WeakPolarHBondContact O-CB 3.25Å; I189-Y193 PolarHBondContact O-N 3.1Å; L190-Y193 PolarHBondContact O-N 3.1Å; I191-Y193 VanDerWaalsContact C-N 3.29Å; I191-Y193 PolarHBondContact O-N 3.01Å
194	F	85.4	Confident	82.3	Confident	120 Å²	120	74.5 Å²	74.5	53%	0.526	36%	0.359	S	S	.	.	H	α-helix	trans	-86.7	-25.8	-176.1	-70.9	-62.8	0	0	0	114.3	L190	L190-F194 HydrophobicContact CD1-CD2 3.85Å; L190-F194 HydrophobicContact CD1-CE2 3.37Å; L190-F194 HydrophobicContact CD1-CZ 4.4Å; L190-F194 HydrophobicContact CD2-CE2 4.45Å; L190-F194 HydrophobicContact CG-CD2 3.81Å; L190-F194 HydrophobicContact CG-CE2 3.74Å; L190-F194 WeakPolarHBondContact O-CD2 3.44Å; L190-F194 PolarHBondContact O-N 2.87Å
195	R	86.7	Confident	82.5	Confident	158 Å²	158	77.7 Å²	77.7	60%	0.596	38%	0.378	S	S	*	.			trans	-146.4	62.7	-168.1	-70	-61.3	-176	-96.1	2.5	111.4	I191 Q197 Y198 S199	I191-R195 CarbonylContact O-C 3.59Å; I191-R195 VanDerWaalsContact O-CA 3.28Å; I191-R195 WeakPolarHBondContact O-CA 3.39Å; I191-R195 PolarHBondContact O-N 3.29Å; R195-Q197 PolarHBondContact O-N 2.89Å; R195-Y198 HydrophobicContact CB-CD2 3.96Å; R195-Y198 PolarHBondContact O-N 2.83Å; R195-S199 PolarHBondContact O-N 3Å
196	P	81.2	Confident	82.6	Confident	68 Å²	68	77.5 Å²	77.5	44%	0.442	38%	0.377	S	S	.	.	H	α-helix	trans	-60.5	-22.3	-175	23.9	-34.9	0	0	0	114.2	S199 K200	P196-S199 PolarHBondContact O-N 3.04Å; P196-K200 PolarHBondContact O-N 3.3Å
197	Q	83.6	Confident	82.6	Confident	156 Å²	156	79.2 Å²	79.2	73%	0.729	38%	0.379	S	S	*	.	H	α-helix	trans	-63.2	-41.1	176.2	-62.5	178.6	4	0	0	112.2	R195	R195-Q197 PolarHBondContact O-N 2.89Å
198	Y	83.9	Confident	82.5	Confident	139 Å²	139	80.4 Å²	80.4	55%	0.545	38%	0.384	S	S	.	.	H	α-helix	trans	-76.4	-34.4	178.7	-68.2	-86.6	0	0	0	111.7	R195 K200 I201 I202	R195-Y198 HydrophobicContact CB-CD2 3.96Å; R195-Y198 PolarHBondContact O-N 2.83Å; Y198-K200 VanDerWaalsContact C-N 3.26Å; Y198-K200 PolarHBondContact O-N 3.47Å; Y198-I201 PolarHBondContact O-N 3.48Å; Y198-I202 WeakPolarHBondContact O-CG1 3.47Å; Y198-I202 PolarHBondContact O-N 3.44Å
199	S	81.9	Confident	82.3	Confident	3 Å²	3	82 Å²	82	2%	0.021	39%	0.393	C	S	.	.	H	α-helix	trans	-53.6	-41.5	175.8	159.2	0	0	0	0	112.7	C61 N192 R195 P196 I201 I202 T203	C61-S199 VanDerWaalsContact CB-OG 3.31Å; C61-S199 WeakPolarHBondContact CB-OG 3.41Å; C61-S199 PolarHBondContact O-OG 3.26Å; N192-S199 WeakPolarHBondContact OD1-CB 3.48Å; N192-S199 PolarHBondContact OD1-OG 3.26Å; R195-S199 PolarHBondContact O-N 3Å; P196-S199 PolarHBondContact O-N 3.04Å; S199-I201 VanDerWaalsContact C-N 3.33Å; S199-I201 PolarHBondContact O-N 3.33Å; S199-I202 PolarHBondContact O-N 2.87Å; S199-T203 VanDerWaalsContact O-CB 3.26Å; S199-T203 WeakPolarHBondContact O-CB 3.34Å; S199-T203 PolarHBondContact O-N 3.46Å; S199-T203 PolarHBondContact O-OG1 3.18Å
200	K	81.5	Confident	82	Confident	163 Å²	163	81.6 Å²	81.6	71%	0.709	39%	0.391	S	S	*	.	H	α-helix	trans	-61	-40.8	177.2	-67.8	-177.5	-178.8	-177.7	0	112.7	P196 Y198 K204	P196-K200 PolarHBondContact O-N 3.3Å; Y198-K200 VanDerWaalsContact C-N 3.26Å; Y198-K200 PolarHBondContact O-N 3.47Å; K200-K204 WeakPolarHBondContact O-CB 3.38Å; K200-K204 PolarHBondContact O-N 2.95Å; K200-K204 VanDerWaalsContact O-N 3.13Å
201	I	85.9	Confident	81.5	Confident	107 Å²	107	82 Å²	82	55%	0.549	39%	0.392	S	S	.	.	H	α-helix	trans	-68.7	-49.5	179	-61.2	169.5	0	0	0	109.5	Y198 S199 T203 K204 V205	Y198-I201 PolarHBondContact O-N 3.48Å; S199-I201 VanDerWaalsContact C-N 3.33Å; S199-I201 PolarHBondContact O-N 3.33Å; I201-T203 VanDerWaalsContact C-N 3.3Å; I201-T203 PolarHBondContact O-N 3.41Å; I201-K204 PolarHBondContact O-N 3.33Å; I201-V205 HydrophobicContact CG2-CG2 4.47Å; I201-V205 WeakPolarHBondContact O-CG2 3.29Å; I201-V205 PolarHBondContact O-N 2.95Å
202	I	83.8	Confident	81.2	Confident	46 Å²	46	84.3 Å²	84.3	24%	0.236	40%	0.404	C	S	.	.	H	α-helix	trans	-60	-42.8	179.9	-63.1	165.9	0	0	0	110.6	V57 S58 I191 Y198 S199 K204 V205 G206	V57-I202 HydrophobicContact CG1-CG2 4.05Å; S58-I202 PolarHBondContact OG-O 3.18Å; I191-I202 HydrophobicContact CD1-CD1 4.36Å; I191-I202 HydrophobicContact CG2-CD1 3.92Å; Y198-I202 WeakPolarHBondContact O-CG1 3.47Å; Y198-I202 PolarHBondContact O-N 3.44Å; S199-I202 PolarHBondContact O-N 2.87Å; I202-K204 PolarHBondContact O-N 3.15Å; I202-V205 PolarHBondContact O-N 3.16Å; I202-G206 PolarHBondContact O-N 2.93Å
203	T	80.9	Confident	80.6	Confident	28 Å²	28	84.6 Å²	84.6	17%	0.172	41%	0.407	C	S	.	.	H	α-helix	trans	-58.7	-47.8	176	-61.3	0	0	0	0	111.5	S58 C61 T62 S199 I201 V205 G206 L207	S58-T203 WeakPolarHBondContact OG-CA 3.4Å; S58-T203 PolarHBondContact OG-O 2.82Å; C61-T203 WeakPolarHBondContact CB-OG1 3.3Å; T62-T203 HydrophobicContact CG2-CG2 3.55Å; S199-T203 VanDerWaalsContact O-CB 3.26Å; S199-T203 WeakPolarHBondContact O-CB 3.34Å; S199-T203 PolarHBondContact O-N 3.46Å; S199-T203 PolarHBondContact O-OG1 3.18Å; I201-T203 VanDerWaalsContact C-N 3.3Å; I201-T203 PolarHBondContact O-N 3.41Å; T203-V205 PolarHBondContact O-N 3.01Å; T203-G206 PolarHBondContact O-N 3.09Å; T203-L207 VanDerWaalsContact O-CB 3.26Å; T203-L207 WeakPolarHBondContact O-CB 3.24Å; T203-L207 PolarHBondContact O-N 3.21Å
204	K	82.6	Confident	80	Confident	158 Å²	158	79.3 Å²	79.3	69%	0.687	39%	0.388	S	S	*	.	H	α-helix	trans	-63.9	-43.4	-179.4	-170.3	173.9	-177.1	178.8	0	111.5	K200 I201 I202 C208	K200-K204 WeakPolarHBondContact O-CB 3.38Å; K200-K204 PolarHBondContact O-N 2.95Å; K200-K204 VanDerWaalsContact O-N 3.13Å; I201-K204 PolarHBondContact O-N 3.33Å; I202-K204 PolarHBondContact O-N 3.15Å; K204-C208 PolarHBondContact O-N 3.37Å
205	V	84.4	Confident	79.5	Confident	77 Å²	77	78.6 Å²	78.6	47%	0.467	39%	0.389	S	S	.	.	H	α-helix	trans	-64.3	-49.6	177.4	173.6	0	0	0	0	110.8	I201 I202 T203 L207 C208 V209	I201-V205 HydrophobicContact CG2-CG2 4.47Å; I201-V205 WeakPolarHBondContact O-CG2 3.29Å; I201-V205 PolarHBondContact O-N 2.95Å; I202-V205 PolarHBondContact O-N 3.16Å; T203-V205 PolarHBondContact O-N 3.01Å; V205-L207 VanDerWaalsContact C-N 3.31Å; V205-L207 PolarHBondContact O-N 3.46Å; V205-C208 WeakPolarHBondContact O-CB 3.13Å; V205-C208 PolarHBondContact O-N 2.84Å; V205-V209 HydrophobicContact CG1-CG2 4.41Å; V205-V209 WeakPolarHBondContact O-CG2 3.49Å; V205-V209 PolarHBondContact O-N 3.37Å
206	G	78.4	Confident	78.8	Confident	2 Å²	2	74.6 Å²	74.6	2%	0.021	38%	0.382	C	S	.	.	H	α-helix	trans	-64.6	-34.3	-179.1	0	0	0	0	0	113.2	S58 I202 T203 V209 L210	S58-G206 WeakPolarHBondContact OG-CA 3.14Å; I202-G206 PolarHBondContact O-N 2.93Å; T203-G206 PolarHBondContact O-N 3.09Å; G206-V209 PolarHBondContact O-N 2.88Å; G206-L210 VanDerWaalsContact O-CB 3.3Å; G206-L210 WeakPolarHBondContact O-CB 3.15Å; G206-L210 PolarHBondContact O-N 3.1Å
207	L	76.6	Confident	78	Confident	65 Å²	65	73 Å²	73	34%	0.34	37%	0.37	S	S	.	.	H	α-helix	trans	-68.7	-41.5	174.1	-156.7	148.4	0	0	0	111.7	T203 V205 L210 M211	T203-L207 VanDerWaalsContact O-CB 3.26Å; T203-L207 WeakPolarHBondContact O-CB 3.24Å; T203-L207 PolarHBondContact O-N 3.21Å; V205-L207 VanDerWaalsContact C-N 3.31Å; V205-L207 PolarHBondContact O-N 3.46Å; L207-L210 PolarHBondContact O-N 3.07Å; L207-M211 HydrophobicContact CD2-CG 4.14Å; L207-M211 WeakPolarHBondContact O-CB 3.28Å; L207-M211 VanDerWaalsContact O-CG 3.27Å; L207-M211 WeakPolarHBondContact O-CG 3.23Å; L207-M211 PolarHBondContact O-N 3.41Å
208	C	81.1	Confident	77.1	Confident	70 Å²	70	66.7 Å²	66.7	47%	0.473	34%	0.342	S	S	.	.	H	α-helix	trans	-58.5	-48.4	170.7	-87.4	0	0	0	0	111.8	K204 V205 L210 M211 I212	K204-C208 PolarHBondContact O-N 3.37Å; V205-C208 WeakPolarHBondContact O-CB 3.13Å; V205-C208 PolarHBondContact O-N 2.84Å; C208-L210 PolarHBondContact O-N 3.24Å; C208-M211 PolarHBondContact O-N 3.11Å; C208-I212 VanDerWaalsContact O-CG1 3.28Å; C208-I212 WeakPolarHBondContact O-CG1 3.25Å; C208-I212 PolarHBondContact O-N 2.87Å
209	V	78.7	Confident	76.5	Confident	33 Å²	33	64.3 Å²	64.3	20%	0.2	34%	0.338	C	S	.	.	H	α-helix	trans	-59.5	-46.7	177.6	171.1	0	0	0	0	110.7	V51 V55 V205 G206 M211 I212 S213	V51-V209 HydrophobicContact CB-CG1 4.5Å; V51-V209 HydrophobicContact CG1-CG1 3.76Å; V51-V209 HydrophobicContact CG2-CG1 4.28Å; V55-V209 HydrophobicContact CG2-CG1 4.23Å; V205-V209 HydrophobicContact CG1-CG2 4.41Å; V205-V209 WeakPolarHBondContact O-CG2 3.49Å; V205-V209 PolarHBondContact O-N 3.37Å; G206-V209 PolarHBondContact O-N 2.88Å; V209-M211 VanDerWaalsContact C-N 3.34Å; V209-M211 PolarHBondContact O-N 3.34Å; V209-I212 PolarHBondContact O-N 3.22Å; V209-S213 PolarHBondContact O-N 3.08Å; V209-S213 PolarHBondContact O-OG 3.39Å; V209-S213 VanDerWaalsContact O-OG 3.06Å
210	L	72.6	Confident	75.7	Confident	11 Å²	11	68.1 Å²	68.1	6%	0.058	36%	0.357	C	S	.	.	H	α-helix	trans	-57.3	-46.3	177.3	177.7	68.5	0	0	0	111.9	V55 G206 L207 C208 S213 I214 Q279 T283 K286	V55-L210 HydrophobicContact CG1-CD1 4.37Å; V55-L210 HydrophobicContact CG2-CB 4.46Å; G206-L210 VanDerWaalsContact O-CB 3.3Å; G206-L210 WeakPolarHBondContact O-CB 3.15Å; G206-L210 PolarHBondContact O-N 3.1Å; L207-L210 PolarHBondContact O-N 3.07Å; C208-L210 PolarHBondContact O-N 3.24Å; L210-S213 PolarHBondContact O-N 3.24Å; L210-I214 HydrophobicContact CD1-CD1 4.3Å; L210-I214 HydrophobicContact CG-CD1 4.08Å; L210-I214 PolarHBondContact O-N 3.31Å; L210-Q279 HydrophobicContact CD2-CG 4.07Å; L210-T283 WeakPolarHBondContact CD2-OG1 3.33Å; L210-K286 HydrophobicContact CD1-CD 3.76Å; L210-K286 PolarHBondContact O-NZ 3.21Å
211	M	72.7	Confident	74.7	Confident	108 Å²	108	61.6 Å²	61.6	53%	0.532	33%	0.332	S	S	.	.	H	α-helix	trans	-64.9	-44.9	179.7	-72.5	-59.5	-66.5	0	0	111.7	L207 C208 V209 S213 I214 L215	L207-M211 HydrophobicContact CD2-CG 4.14Å; L207-M211 WeakPolarHBondContact O-CB 3.28Å; L207-M211 VanDerWaalsContact O-CG 3.27Å; L207-M211 WeakPolarHBondContact O-CG 3.23Å; L207-M211 PolarHBondContact O-N 3.41Å; C208-M211 PolarHBondContact O-N 3.11Å; V209-M211 VanDerWaalsContact C-N 3.34Å; V209-M211 PolarHBondContact O-N 3.34Å; M211-S213 VanDerWaalsContact C-N 3.31Å; M211-S213 PolarHBondContact O-N 2.88Å; M211-I214 PolarHBondContact O-N 3.32Å; M211-L215 WeakPolarHBondContact O-CB 3.41Å; M211-L215 PolarHBondContact O-N 3.41Å
212	I	79.8	Confident	73.7	Confident	104 Å²	104	61 Å²	61	53%	0.533	33%	0.329	S	S	.	.	H	α-helix	trans	-59.8	-44.4	175	-67.2	165.2	0	0	0	109.9	C208 V209 I214 L215 V216	C208-I212 VanDerWaalsContact O-CG1 3.28Å; C208-I212 WeakPolarHBondContact O-CG1 3.25Å; C208-I212 PolarHBondContact O-N 2.87Å; V209-I212 PolarHBondContact O-N 3.22Å; I212-I214 PolarHBondContact O-N 2.86Å; I212-L215 WeakPolarHBondContact O-CB 3.29Å; I212-L215 PolarHBondContact O-N 3.08Å; I212-L215 VanDerWaalsContact O-N 3.14Å; I212-V216 HydrophobicContact CG2-CG2 4.24Å; I212-V216 WeakPolarHBondContact O-CG2 3.46Å; I212-V216 PolarHBondContact O-N 3.36Å
213	S	69.3	Low	72.9	Confident	31 Å²	31	64.3 Å²	64.3	22%	0.217	35%	0.351	C	S	.	.	H	α-helix	trans	-65.2	-35.2	176.5	-57.9	0	0	0	0	113	V209 L210 M211 L215 I217	V209-S213 PolarHBondContact O-N 3.08Å; V209-S213 PolarHBondContact O-OG 3.39Å; V209-S213 VanDerWaalsContact O-OG 3.06Å; L210-S213 PolarHBondContact O-N 3.24Å; M211-S213 VanDerWaalsContact C-N 3.31Å; M211-S213 PolarHBondContact O-N 2.88Å; S213-L215 VanDerWaalsContact C-N 3.32Å; S213-I217 WeakPolarHBondContact O-CB 3.33Å; S213-I217 WeakPolarHBondContact O-CD1 3.35Å; S213-I217 WeakPolarHBondContact O-CG1 3.24Å; S213-I217 PolarHBondContact O-N 2.88Å
214	I	69.8	Low	71.9	Confident	19 Å²	19	70 Å²	70	10%	0.097	38%	0.376	C	S	.	.	H	α-helix	trans	-60.7	-49.5	171.2	-94.1	121.9	0	0	0	107.9	L210 M211 I212 V216 I217 C218 K286	L210-I214 HydrophobicContact CD1-CD1 4.3Å; L210-I214 HydrophobicContact CG-CD1 4.08Å; L210-I214 PolarHBondContact O-N 3.31Å; M211-I214 PolarHBondContact O-N 3.32Å; I212-I214 PolarHBondContact O-N 2.86Å; I214-V216 PolarHBondContact O-N 3.35Å; I214-I217 PolarHBondContact O-N 3.49Å; I214-C218 WeakPolarHBondContact O-CB 3.36Å; I214-C218 PolarHBondContact O-N 3.33Å; I214-C218 PolarHBondContact O-SG 3.44Å; I214-K286 VanDerWaalsContact CA-NZ 3.31Å
215	L	73.6	Confident	70.6	Confident	105 Å²	105	65.7 Å²	65.7	55%	0.55	36%	0.36	S	S	.	.	H	α-helix	trans	-63.7	-45.4	-173.2	-173.8	70.5	0	0	0	111.7	M211 I212 S213 I217 C218 I219	M211-L215 WeakPolarHBondContact O-CB 3.41Å; M211-L215 PolarHBondContact O-N 3.41Å; I212-L215 WeakPolarHBondContact O-CB 3.29Å; I212-L215 PolarHBondContact O-N 3.08Å; I212-L215 VanDerWaalsContact O-N 3.14Å; S213-L215 VanDerWaalsContact C-N 3.32Å; L215-I217 PolarHBondContact O-N 3.33Å; L215-C218 WeakPolarHBondContact O-CB 3.47Å; L215-C218 PolarHBondContact O-N 2.99Å; L215-I219 HydrophobicContact CD1-CD1 4.39Å; L215-I219 HydrophobicContact CG-CD1 3.94Å; L215-I219 VanDerWaalsContact O-CG1 3.25Å; L215-I219 WeakPolarHBondContact O-CG1 3.47Å; L215-I219 PolarHBondContact O-N 2.91Å
216	V	72.2	Confident	69.1	Low	73 Å²	73	65.3 Å²	65.3	44%	0.442	37%	0.371	S	S	.	.	H	α-helix	trans	-60.8	-46.7	177.7	171	0	0	0	0	110.6	I212 I214 C218 I219 I220	I212-V216 HydrophobicContact CG2-CG2 4.24Å; I212-V216 WeakPolarHBondContact O-CG2 3.46Å; I212-V216 PolarHBondContact O-N 3.36Å; I214-V216 PolarHBondContact O-N 3.35Å; V216-C218 VanDerWaalsContact C-N 3.35Å; V216-C218 PolarHBondContact O-N 3.07Å; V216-I219 PolarHBondContact O-N 3.33Å; V216-I220 HydrophobicContact CG1-CD1 3.75Å; V216-I220 HydrophobicContact CG1-CG1 4.49Å; V216-I220 VanDerWaalsContact O-CG1 3.27Å; V216-I220 WeakPolarHBondContact O-CG1 3.29Å; V216-I220 PolarHBondContact O-N 2.85Å
217	I	64.1	Low	68	Low	36 Å²	36	69 Å²	69	19%	0.185	40%	0.396	C	S	.	.	H	α-helix	trans	-67.5	-37.5	178.5	-61.6	168.5	0	0	0	110.7	S213 I214 L215 I220 S221 Y298	S213-I217 WeakPolarHBondContact O-CB 3.33Å; S213-I217 WeakPolarHBondContact O-CD1 3.35Å; S213-I217 WeakPolarHBondContact O-CG1 3.24Å; S213-I217 PolarHBondContact O-N 2.88Å; I214-I217 PolarHBondContact O-N 3.49Å; L215-I217 PolarHBondContact O-N 3.33Å; I217-I220 PolarHBondContact O-N 2.95Å; I217-S221 WeakPolarHBondContact O-CB 3.43Å; I217-S221 PolarHBondContact O-N 3.33Å; I217-S221 PolarHBondContact O-OG 3.37Å; I217-Y298 HydrophobicContact CB-CE1 4.46Å; I217-Y298 HydrophobicContact CB-CE2 4.47Å; I217-Y298 HydrophobicContact CG2-CD1 3.71Å; I217-Y298 HydrophobicContact CG2-CE1 3.39Å; I217-Y298 HydrophobicContact CG2-CE2 4.18Å; I217-Y298 HydrophobicContact CG2-CG 4.32Å
218	C	65.6	Low	67	Low	22 Å²	22	67 Å²	67	15%	0.149	39%	0.388	C	S	.	.	H	α-helix	trans	-56.9	-49.1	170.4	-76.7	0	0	0	0	112	I214 L215 V216 S221 I222 Y298 L299	I214-C218 WeakPolarHBondContact O-CB 3.36Å; I214-C218 PolarHBondContact O-N 3.33Å; I214-C218 PolarHBondContact O-SG 3.44Å; L215-C218 WeakPolarHBondContact O-CB 3.47Å; L215-C218 PolarHBondContact O-N 2.99Å; V216-C218 VanDerWaalsContact C-N 3.35Å; V216-C218 PolarHBondContact O-N 3.07Å; C218-S221 PolarHBondContact O-N 3.04Å; C218-I222 HydrophobicContact CB-CD1 4.46Å; C218-I222 VanDerWaalsContact O-CB 3.29Å; C218-I222 WeakPolarHBondContact O-CB 3.23Å; C218-I222 WeakPolarHBondContact O-CD1 3.2Å; C218-I222 WeakPolarHBondContact O-CG1 3.36Å; C218-I222 PolarHBondContact O-N 3.41Å; C218-Y298 WeakPolarHBondContact CA-OH 3.26Å; C218-Y298 PolarHBondContact N-OH 3.47Å; C218-Y298 PolarHBondContact SG-OH 2.84Å; C218-L299 VanDerWaalsContact SG-CD2 3.57Å
219	I	70.4	Confident	65.9	Low	90 Å²	90	67.7 Å²	67.7	46%	0.462	39%	0.387	S	S	.	.	H	α-helix	trans	-63.4	-46.5	-179.4	-67.7	164.6	0	0	0	109.7	L215 V216 S221 I222 V223	L215-I219 HydrophobicContact CD1-CD1 4.39Å; L215-I219 HydrophobicContact CG-CD1 3.94Å; L215-I219 VanDerWaalsContact O-CG1 3.25Å; L215-I219 WeakPolarHBondContact O-CG1 3.47Å; L215-I219 PolarHBondContact O-N 2.91Å; V216-I219 PolarHBondContact O-N 3.33Å; I219-S221 VanDerWaalsContact C-N 3.34Å; I219-S221 PolarHBondContact O-N 3.34Å; I219-I222 PolarHBondContact O-N 3.07Å; I219-V223 HydrophobicContact CG2-CG2 4.23Å; I219-V223 VanDerWaalsContact O-CB 3.31Å; I219-V223 WeakPolarHBondContact O-CB 3.39Å; I219-V223 WeakPolarHBondContact O-CG2 3.35Å; I219-V223 PolarHBondContact O-N 3.08Å
220	I	66.7	Low	65	Low	83 Å²	83	72.1 Å²	72.1	43%	0.426	41%	0.408	S	S	.	.	H	α-helix	trans	-59.1	-46.4	175.8	-66	166.4	0	0	0	110.5	V216 I217 I222 V223 E224	V216-I220 HydrophobicContact CG1-CD1 3.75Å; V216-I220 HydrophobicContact CG1-CG1 4.49Å; V216-I220 VanDerWaalsContact O-CG1 3.27Å; V216-I220 WeakPolarHBondContact O-CG1 3.29Å; V216-I220 PolarHBondContact O-N 2.85Å; I217-I220 PolarHBondContact O-N 2.95Å; I220-I222 PolarHBondContact O-N 3.37Å; I220-V223 PolarHBondContact O-N 3.18Å; I220-E224 HydrophobicContact CG2-CG 4.33Å; I220-E224 VanDerWaalsContact O-CB 3.31Å; I220-E224 WeakPolarHBondContact O-CB 3.31Å; I220-E224 WeakPolarHBondContact O-CG 3.37Å; I220-E224 PolarHBondContact O-N 3.42Å
221	S	60.1	Low	64.7	Low	26 Å²	26	74.5 Å²	74.5	18%	0.182	42%	0.423	C	S	.	.	H	α-helix	trans	-64.8	-37.7	179.6	-57.5	0	0	0	0	112.6	I217 C218 I219 I225 Y298	I217-S221 WeakPolarHBondContact O-CB 3.43Å; I217-S221 PolarHBondContact O-N 3.33Å; I217-S221 PolarHBondContact O-OG 3.37Å; C218-S221 PolarHBondContact O-N 3.04Å; I219-S221 VanDerWaalsContact C-N 3.34Å; I219-S221 PolarHBondContact O-N 3.34Å; S221-I225 CarbonylContact O-C 3.54Å; S221-I225 WeakPolarHBondContact O-CA 3.33Å; S221-I225 PolarHBondContact O-N 3.5Å; S221-Y298 PolarHBondContact OG-OH 3.22Å
222	I	65.2	Low	64.5	Low	94 Å²	94	69.9 Å²	69.9	48%	0.482	40%	0.401	S	S	.	.	H	α-helix	trans	-70.5	-40.9	177.1	-70.7	163.3	0	0	0	110.5	C218 I219 I220 L229	C218-I222 HydrophobicContact CB-CD1 4.46Å; C218-I222 VanDerWaalsContact O-CB 3.29Å; C218-I222 WeakPolarHBondContact O-CB 3.23Å; C218-I222 WeakPolarHBondContact O-CD1 3.2Å; C218-I222 WeakPolarHBondContact O-CG1 3.36Å; C218-I222 PolarHBondContact O-N 3.41Å; I219-I222 PolarHBondContact O-N 3.07Å; I220-I222 PolarHBondContact O-N 3.37Å; I222-L229 HydrophobicContact CG1-CD1 4.39Å
223	V	65.6	Low	64	Low	116 Å²	116	70.1 Å²	70.1	70%	0.703	40%	0.402	S	S	*	.	H	α-helix	trans	-72.4	-39.5	179.9	171	0	0	0	0	111.4	I219 I220	I219-V223 HydrophobicContact CG2-CG2 4.23Å; I219-V223 VanDerWaalsContact O-CB 3.31Å; I219-V223 WeakPolarHBondContact O-CB 3.39Å; I219-V223 WeakPolarHBondContact O-CG2 3.35Å; I219-V223 PolarHBondContact O-N 3.08Å; I220-V223 PolarHBondContact O-N 3.18Å
224	E	60.3	Low	64.7	Low	147 Å²	147	70.1 Å²	70.1	69%	0.687	40%	0.403	S	S	*	.	H	α-helix	trans	-77.4	-32.7	177.6	-75.7	-176.3	151.6	0	0	112.2	I220	I220-E224 HydrophobicContact CG2-CG 4.33Å; I220-E224 VanDerWaalsContact O-CB 3.31Å; I220-E224 WeakPolarHBondContact O-CB 3.31Å; I220-E224 WeakPolarHBondContact O-CG 3.37Å; I220-E224 PolarHBondContact O-N 3.42Å
225	I	55.2	Low	65.6	Low	68 Å²	68	74.2 Å²	74.2	35%	0.349	43%	0.43	S	S	.	.			trans	-150.3	86.5	-172.2	-41	174.2	0	0	0	113.1	S221 S227 S228	S221-I225 CarbonylContact O-C 3.54Å; S221-I225 WeakPolarHBondContact O-CA 3.33Å; S221-I225 PolarHBondContact O-N 3.5Å; I225-S227 WeakPolarHBondContact CG2-OG 3.38Å; I225-S227 PolarHBondContact O-N 3.29Å; I225-S227 VanDerWaalsContact O-N 3.11Å; I225-S228 WeakPolarHBondContact CD1-OG 3.47Å; I225-S228 VanDerWaalsContact CG2-N 3.27Å; I225-S228 WeakPolarHBondContact CG2-OG 3.5Å; I225-S228 PolarHBondContact O-N 3.02Å; I225-S228 VanDerWaalsContact O-N 3.16Å
226	G	53.4	Low	66.4	Low	68 Å²	68	71.1 Å²	71.1	70%	0.701	42%	0.416	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.7	-17.5	165.9	0	0	0	0	0	114.3
227	S	54.1	Low	67.2	Low	80 Å²	80	68 Å²	68	56%	0.559	40%	0.397	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.3	-12	176.5	50.7	0	0	0	0	115.2	I225 L230	I225-S227 WeakPolarHBondContact CG2-OG 3.38Å; I225-S227 PolarHBondContact O-N 3.29Å; I225-S227 VanDerWaalsContact O-N 3.11Å; S227-L230 WeakPolarHBondContact O-CB 3.47Å
228	S	57.3	Low	68.6	Low	22 Å²	22	69.8 Å²	69.8	15%	0.154	41%	0.406	C	S	.	.	T	Hydrogen-bonded Turn	trans	-84.8	-19	-177.7	-85.9	0	0	0	0	113.5	I225 L230 T231	I225-S228 WeakPolarHBondContact CD1-OG 3.47Å; I225-S228 VanDerWaalsContact CG2-N 3.27Å; I225-S228 WeakPolarHBondContact CG2-OG 3.5Å; I225-S228 PolarHBondContact O-N 3.02Å; I225-S228 VanDerWaalsContact O-N 3.16Å; S228-L230 PolarHBondContact O-N 3.45Å; S228-T231 WeakPolarHBondContact O-CB 3.48Å; S228-T231 PolarHBondContact O-N 2.96Å; S228-T231 PolarHBondContact O-OG1 3.01Å
229	L	56.5	Low	70	Confident	86 Å²	86	70.2 Å²	70.2	45%	0.45	41%	0.411	S	S	.	.	H	α-helix	trans	-61.6	-31.2	169.6	-73.9	-178.4	0	0	0	111.8	I222 T231 M232 L233 L299	I222-L229 HydrophobicContact CG1-CD1 4.39Å; L229-T231 PolarHBondContact O-N 3.36Å; L229-M232 PolarHBondContact O-N 3.32Å; L229-L233 PolarHBondContact O-N 2.86Å; L229-L299 HydrophobicContact CD2-CD1 3.85Å
230	L	60.5	Low	71.1	Confident	125 Å²	125	66 Å²	66	65%	0.654	39%	0.389	S	S	*	.	H	α-helix	trans	-63.5	-27.3	172.8	-66.8	173	0	0	0	112.4	S227 S228 M232 L233 S234	S227-L230 WeakPolarHBondContact O-CB 3.47Å; S228-L230 PolarHBondContact O-N 3.45Å; L230-M232 VanDerWaalsContact C-N 3.34Å; L230-M232 PolarHBondContact O-N 3.24Å; L230-L233 CarbonylContact O-C 3.49Å; L230-L233 PolarHBondContact O-N 3.15Å; L230-S234 PolarHBondContact O-N 3.45Å
231	T	66	Low	72.4	Confident	61 Å²	61	62 Å²	62	37%	0.374	37%	0.369	S	S	.	.	H	α-helix	trans	-68	-34	176.3	67.9	0	0	0	0	112	S228 L229 L233 S234 L237 P296	S228-T231 WeakPolarHBondContact O-CB 3.48Å; S228-T231 PolarHBondContact O-N 2.96Å; S228-T231 PolarHBondContact O-OG1 3.01Å; L229-T231 PolarHBondContact O-N 3.36Å; T231-L233 VanDerWaalsContact C-N 3.3Å; T231-S234 WeakPolarHBondContact O-CB 3.3Å; T231-S234 PolarHBondContact O-N 2.83Å; T231-S234 VanDerWaalsContact O-N 3.17Å; T231-S234 PolarHBondContact O-OG 2.95Å; T231-L237 WeakPolarHBondContact O-CD1 3.26Å; T231-P296 WeakPolarHBondContact OG1-CG 3.43Å
232	M	68	Low	74.1	Confident	12 Å²	12	63 Å²	63	6%	0.059	37%	0.374	C	S	.	.	H	α-helix	trans	-71	-26.9	172.7	-64.5	-58.9	93.5	0	0	112.7	L229 L230 S234 L237 P296 M297 L299	L229-M232 PolarHBondContact O-N 3.32Å; L230-M232 VanDerWaalsContact C-N 3.34Å; L230-M232 PolarHBondContact O-N 3.24Å; M232-S234 PolarHBondContact O-N 3.4Å; M232-L237 HydrophobicContact CE-CD1 3.84Å; M232-P296 HydrophobicContact CE-CB 3.78Å; M232-P296 HydrophobicContact CE-CG 3.68Å; M232-P296 HydrophobicContact CG-CB 4.04Å; M232-P296 HydrophobicContact SD-CB 4.14Å; M232-M297 HydrophobicContact CE-CG 4.15Å; M232-M297 HydrophobicContact CE-SD 3.46Å; M232-M297 WeakPolarHBondContact CE-SD 3.37Å; M232-M297 HydrophobicContact SD-SD 4.07Å; M232-L299 HydrophobicContact CG-CB 4.32Å; M232-L299 HydrophobicContact CG-CD1 4.37Å; M232-L299 HydrophobicContact SD-CB 4.37Å
233	L	70.4	Confident	75.6	Confident	108 Å²	108	61.3 Å²	61.3	57%	0.565	37%	0.365	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.1	9.7	171.8	-99.1	69.9	0	0	0	113.1	L229 L230 T231 M238	L229-L233 PolarHBondContact O-N 2.86Å; L230-L233 CarbonylContact O-C 3.49Å; L230-L233 PolarHBondContact O-N 3.15Å; T231-L233 VanDerWaalsContact C-N 3.3Å; L233-M238 HydrophobicContact CB-SD 4.47Å; L233-M238 HydrophobicContact CG-SD 4.23Å
234	S	84.2	Confident	77	Confident	32 Å²	32	55.9 Å²	55.9	22%	0.224	33%	0.332	C	S	.	.			trans	-60.8	138	177.3	62.7	0	0	0	0	110.3	L230 T231 M232 P236 L237 M238	L230-S234 PolarHBondContact O-N 3.45Å; T231-S234 WeakPolarHBondContact O-CB 3.3Å; T231-S234 PolarHBondContact O-N 2.83Å; T231-S234 VanDerWaalsContact O-N 3.17Å; T231-S234 PolarHBondContact O-OG 2.95Å; M232-S234 PolarHBondContact O-N 3.4Å; S234-P236 VanDerWaalsContact C-N 3.34Å; S234-L237 PolarHBondContact O-N 2.84Å; S234-L237 VanDerWaalsContact O-N 3.07Å; S234-L237 WeakPolarHBondContact OG-CD1 2.96Å; S234-L237 VanDerWaalsContact OG-CG 3.28Å; S234-L237 WeakPolarHBondContact OG-CG 3.28Å; S234-M238 PolarHBondContact O-N 3.39Å
235	P	88.1	Confident	78.7	Confident	105 Å²	105	48.9 Å²	48.9	68%	0.682	30%	0.3	S	S	*	.	H	α-helix	trans	-48.4	-43.3	-179.8	-28.3	34.2	0	0	0	115.3	A239	P235-A239 VanDerWaalsContact O-CB 3.29Å; P235-A239 WeakPolarHBondContact O-CB 3.39Å; P235-A239 PolarHBondContact O-N 2.83Å
236	P	90.2	Very high	80.6	Confident	39 Å²	39	49.4 Å²	49.4	25%	0.253	30%	0.303	S	S	.	.	H	α-helix	trans	-67.4	-37.7	179.4	26.1	-35.1	0	0	0	112.9	F100 L102 S234 A239 I240	F100-P236 HydrophobicContact CB-CB 4.19Å; F100-P236 HydrophobicContact CD1-CB 3.67Å; F100-P236 HydrophobicContact CE1-CB 4.36Å; F100-P236 HydrophobicContact CG-CB 4.15Å; L102-P236 HydrophobicContact CD2-CB 4.1Å; L102-P236 HydrophobicContact CD2-CG 4.43Å; S234-P236 VanDerWaalsContact C-N 3.34Å; P236-A239 PolarHBondContact O-N 3.29Å; P236-I240 VanDerWaalsContact O-CG1 3.23Å; P236-I240 WeakPolarHBondContact O-CG1 3.42Å; P236-I240 PolarHBondContact O-N 3.27Å
237	L	90.3	Very high	82.7	Confident	9 Å²	9	48 Å²	48	5%	0.047	28%	0.279	C	S	.	.	H	α-helix	trans	-69.4	-41.1	178	-67.7	-176.3	0	0	0	111.8	L102 T106 I110 T231 M232 S234 I240 A241 M297 F300	L102-L237 HydrophobicContact CD1-CD2 4.39Å; T106-L237 HydrophobicContact CG2-CD2 3.62Å; I110-L237 HydrophobicContact CD1-CD2 4.05Å; T231-L237 WeakPolarHBondContact O-CD1 3.26Å; M232-L237 HydrophobicContact CE-CD1 3.84Å; S234-L237 PolarHBondContact O-N 2.84Å; S234-L237 VanDerWaalsContact O-N 3.07Å; S234-L237 WeakPolarHBondContact OG-CD1 2.96Å; S234-L237 VanDerWaalsContact OG-CG 3.28Å; S234-L237 WeakPolarHBondContact OG-CG 3.28Å; L237-I240 PolarHBondContact O-N 3.1Å; L237-A241 WeakPolarHBondContact O-CB 3.28Å; L237-A241 PolarHBondContact O-N 3.02Å; L237-M297 HydrophobicContact CD1-SD 3.89Å; L237-M297 HydrophobicContact CD2-CE 4.31Å; L237-M297 HydrophobicContact CD2-SD 4.44Å; L237-F300 HydrophobicContact CB-CE2 4.31Å; L237-F300 HydrophobicContact CD2-CD2 4.42Å; L237-F300 HydrophobicContact CD2-CE2 4.27Å
238	M	92.4	Very high	84.6	Confident	73 Å²	73	44.2 Å²	44.2	36%	0.36	25%	0.252	S	S	.	.	H	α-helix	trans	-62.9	-43.6	173.9	-71.6	-168.9	65.5	0	0	111.7	L233 S234 I240 A241 V242 F307	L233-M238 HydrophobicContact CB-SD 4.47Å; L233-M238 HydrophobicContact CG-SD 4.23Å; S234-M238 PolarHBondContact O-N 3.39Å; M238-I240 VanDerWaalsContact C-N 3.31Å; M238-I240 PolarHBondContact O-N 3.09Å; M238-A241 PolarHBondContact O-N 3.04Å; M238-V242 WeakPolarHBondContact O-CG2 3.22Å; M238-V242 PolarHBondContact O-N 3.34Å; M238-V242 VanDerWaalsContact O-N 3.08Å; M238-F307 HydrophobicContact CE-CZ 3.99Å
239	A	94.3	Very high	86.5	Confident	31 Å²	31	43.5 Å²	43.5	26%	0.256	25%	0.246	S	C	.	.	H	α-helix	trans	-58.9	-43.8	176.2	0	0	0	0	0	111.1	F100 P235 P236 V242 L243	F100-A239 HydrophobicContact CE1-CB 4.06Å; F100-A239 HydrophobicContact CE2-CB 4.45Å; F100-A239 HydrophobicContact CZ-CB 3.71Å; P235-A239 VanDerWaalsContact O-CB 3.29Å; P235-A239 WeakPolarHBondContact O-CB 3.39Å; P235-A239 PolarHBondContact O-N 2.83Å; P236-A239 PolarHBondContact O-N 3.29Å; A239-V242 PolarHBondContact O-N 2.91Å; A239-L243 VanDerWaalsContact O-CB 3.22Å; A239-L243 WeakPolarHBondContact O-CB 3.45Å; A239-L243 WeakPolarHBondContact O-CG 3.42Å; A239-L243 PolarHBondContact O-N 3Å
240	I	94.7	Very high	88.3	Confident	0 Å²	0	41.6 Å²	41.6	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-67.9	-39.8	177.6	-67.3	172.9	0	0	0	111.8	L96 F100 L102 I110 P236 L237 M238 V242 L243 L244 F300	L96-I240 HydrophobicContact CB-CD1 4.37Å; L96-I240 HydrophobicContact CB-CG1 4.16Å; L96-I240 HydrophobicContact CD1-CG2 4.22Å; F100-I240 HydrophobicContact CB-CD1 4.21Å; F100-I240 HydrophobicContact CD2-CD1 3.76Å; F100-I240 HydrophobicContact CD2-CG1 3.65Å; F100-I240 HydrophobicContact CE2-CD1 4.49Å; F100-I240 HydrophobicContact CE2-CG1 3.89Å; F100-I240 HydrophobicContact CG-CD1 4.17Å; F100-I240 HydrophobicContact CG-CG1 4.38Å; L102-I240 HydrophobicContact CD1-CD1 3.47Å; L102-I240 VanDerWaalsContact CD1-CD1 3.47Å; L102-I240 HydrophobicContact CG-CD1 4.33Å; I110-I240 HydrophobicContact CD1-CD1 3.93Å; I110-I240 HydrophobicContact CD1-CG2 4.18Å; I110-I240 HydrophobicContact CG1-CG2 4.38Å; I110-I240 HydrophobicContact CG2-CG2 3.87Å; P236-I240 VanDerWaalsContact O-CG1 3.23Å; P236-I240 WeakPolarHBondContact O-CG1 3.42Å; P236-I240 PolarHBondContact O-N 3.27Å; L237-I240 PolarHBondContact O-N 3.1Å; M238-I240 VanDerWaalsContact C-N 3.31Å; M238-I240 PolarHBondContact O-N 3.09Å; I240-V242 PolarHBondContact O-N 3.25Å; I240-L243 PolarHBondContact O-N 3.02Å; I240-L244 WeakPolarHBondContact O-CB 3.44Å; I240-L244 PolarHBondContact O-N 3.43Å; I240-F300 HydrophobicContact CG2-CZ 4.06Å
241	A	93.8	Very high	89.9	Confident	0 Å²	0	40.5 Å²	40.5	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-62.9	-29.4	178.7	0	0	0	0	0	112.8	L237 M238 P245 F300 V303 F307	L237-A241 WeakPolarHBondContact O-CB 3.28Å; L237-A241 PolarHBondContact O-N 3.02Å; M238-A241 PolarHBondContact O-N 3.04Å; A241-P245 WeakPolarHBondContact O-CD 3.45Å; A241-P245 WeakPolarHBondContact O-CG 3.49Å; A241-F300 HydrophobicContact CB-CE2 4.22Å; A241-F300 HydrophobicContact CB-CZ 4.37Å; A241-V303 HydrophobicContact CB-CG1 3.94Å; A241-F307 HydrophobicContact CB-CD2 3.63Å; A241-F307 HydrophobicContact CB-CE2 4.11Å; A241-F307 HydrophobicContact CB-CG 4.49Å; A241-F307 WeakPolarHBondContact O-CB 3.39Å
242	V	95.9	Very high	91.3	Very high	48 Å²	48	37.6 Å²	37.6	29%	0.291	22%	0.215	S	C	.	.	H	α-helix	trans	-82.6	-47.8	171.8	172.9	0	0	0	0	111.4	M238 A239 I240 L244 P245 L246 F307 E311	M238-V242 WeakPolarHBondContact O-CG2 3.22Å; M238-V242 PolarHBondContact O-N 3.34Å; M238-V242 VanDerWaalsContact O-N 3.08Å; A239-V242 PolarHBondContact O-N 2.91Å; I240-V242 PolarHBondContact O-N 3.25Å; V242-L244 PolarHBondContact O-N 2.9Å; V242-P245 WeakPolarHBondContact O-CD 3.35Å; V242-L246 WeakPolarHBondContact O-CB 3.41Å; V242-L246 PolarHBondContact O-N 3.33Å; V242-F307 HydrophobicContact CG2-CD1 3.4Å; V242-F307 VanDerWaalsContact CG2-CD1 3.4Å; V242-F307 HydrophobicContact CG2-CD2 4.28Å; V242-F307 HydrophobicContact CG2-CE1 3.49Å; V242-F307 VanDerWaalsContact CG2-CE1 3.49Å; V242-F307 HydrophobicContact CG2-CE2 4.35Å; V242-F307 HydrophobicContact CG2-CG 3.82Å; V242-F307 HydrophobicContact CG2-CZ 3.98Å; V242-E311 WeakPolarHBondContact CA-OE1 3.04Å; V242-E311 WeakPolarHBondContact CG1-OE1 3.12Å
243	L	96.5	Very high	92.5	Very high	58 Å²	58	41 Å²	41	30%	0.304	23%	0.228	S	C	.	.	H	α-helix	trans	-68.8	-37.3	-173.1	-72.7	171.2	0	0	0	112.5	L96 F100 A239 I240 L246 I247	L96-L243 HydrophobicContact CD1-CB 4.14Å; L96-L243 HydrophobicContact CD2-CB 4.21Å; L96-L243 HydrophobicContact CD2-CD1 3.96Å; F100-L243 HydrophobicContact CE2-CD1 4.15Å; F100-L243 HydrophobicContact CZ-CD1 4.26Å; A239-L243 VanDerWaalsContact O-CB 3.22Å; A239-L243 WeakPolarHBondContact O-CB 3.45Å; A239-L243 WeakPolarHBondContact O-CG 3.42Å; A239-L243 PolarHBondContact O-N 3Å; I240-L243 PolarHBondContact O-N 3.02Å; L243-L246 PolarHBondContact O-N 3.46Å; L243-I247 HydrophobicContact CB-CD1 4.13Å; L243-I247 WeakPolarHBondContact O-CB 3.31Å; L243-I247 WeakPolarHBondContact O-CD1 3.26Å; L243-I247 WeakPolarHBondContact O-CG1 3.13Å; L243-I247 PolarHBondContact O-N 3.26Å
244	L	95.4	Very high	93.6	Very high	1 Å²	1	40 Å²	40	1%	0.005	22%	0.222	C	C	.	.	H	α-helix	trans	-63.6	-51.7	-174.2	-173.7	73.7	0	0	0	112.1	M89 T92 A93 L96 I240 V242 G248 L304	M89-L244 HydrophobicContact CE-CG 4.22Å; T92-L244 HydrophobicContact CG2-CD1 3.8Å; A93-L244 HydrophobicContact CB-CD1 4Å; L96-L244 HydrophobicContact CD1-CB 4.14Å; L96-L244 HydrophobicContact CD1-CD1 4.13Å; I240-L244 WeakPolarHBondContact O-CB 3.44Å; I240-L244 PolarHBondContact O-N 3.43Å; V242-L244 PolarHBondContact O-N 2.9Å; L244-G248 PolarHBondContact O-N 3.32Å; L244-G248 VanDerWaalsContact O-N 3.11Å; L244-L304 HydrophobicContact CB-CD1 4.19Å; L244-L304 HydrophobicContact CD2-CD1 3.98Å; L244-L304 HydrophobicContact CD2-CD2 4.15Å
245	P	95.3	Very high	94	Very high	1 Å²	1	39.8 Å²	39.8	1%	0.006	22%	0.218	C	C	.	.	H	α-helix	trans	-66.3	-41.5	175	-17.3	32.5	0	0	0	112	A241 V242 I247 G248 Y249 L304 Q308	A241-P245 WeakPolarHBondContact O-CD 3.45Å; A241-P245 WeakPolarHBondContact O-CG 3.49Å; V242-P245 WeakPolarHBondContact O-CD 3.35Å; P245-I247 PolarHBondContact O-N 2.75Å; P245-G248 CarbonylContact O-C 3.48Å; P245-G248 WeakPolarHBondContact O-CA 3.16Å; P245-G248 PolarHBondContact O-N 3.3Å; P245-Y249 HydrophobicContact CB-CD2 4.46Å; P245-Y249 HydrophobicContact CB-CE2 3.91Å; P245-Y249 WeakPolarHBondContact O-CD2 3.49Å; P245-Y249 PolarHBondContact O-N 3.29Å; P245-L304 HydrophobicContact CG-CD1 3.63Å; P245-L304 HydrophobicContact CG-CG 4.41Å; P245-Q308 HydrophobicContact CB-CB 4.07Å; P245-Q308 HydrophobicContact CB-CG 4.32Å; P245-Q308 HydrophobicContact CG-CB 3.99Å
246	L	96.1	Very high	94.1	Very high	79 Å²	79	34.8 Å²	34.8	41%	0.414	19%	0.186	S	C	.	.	H	α-helix	trans	-59.4	-47.1	-179.2	-175.5	64.6	0	0	0	112.5	V242 L243 G248 Y249 A250 E311	V242-L246 WeakPolarHBondContact O-CB 3.41Å; V242-L246 PolarHBondContact O-N 3.33Å; L243-L246 PolarHBondContact O-N 3.46Å; L246-G248 VanDerWaalsContact C-N 3.3Å; L246-Y249 PolarHBondContact O-N 2.96Å; L246-A250 WeakPolarHBondContact O-CB 3.44Å; L246-A250 PolarHBondContact O-N 3.16Å; L246-E311 VanDerWaalsContact CA-OE2 3.32Å; L246-E311 WeakPolarHBondContact CA-OE2 3.41Å; L246-E311 WeakPolarHBondContact CB-OE2 3.28Å; L246-E311 PolarHBondContact N-OE2 3.28Å
247	I	96.3	Very high	94.2	Very high	39 Å²	39	40.1 Å²	40.1	20%	0.2	20%	0.201	C	C	.	.	H	α-helix	trans	-62.6	-42.1	175	-68.7	168.7	0	0	0	109.4	T92 L96 L243 P245 Y249 A250 F251	T92-I247 HydrophobicContact CG2-CB 3.94Å; T92-I247 HydrophobicContact CG2-CD1 3.7Å; T92-I247 HydrophobicContact CG2-CG1 4.44Å; T92-I247 HydrophobicContact CG2-CG2 3.58Å; L96-I247 HydrophobicContact CD1-CD1 4.45Å; L96-I247 HydrophobicContact CD2-CD1 4.46Å; L243-I247 HydrophobicContact CB-CD1 4.13Å; L243-I247 WeakPolarHBondContact O-CB 3.31Å; L243-I247 WeakPolarHBondContact O-CD1 3.26Å; L243-I247 WeakPolarHBondContact O-CG1 3.13Å; L243-I247 PolarHBondContact O-N 3.26Å; P245-I247 PolarHBondContact O-N 2.75Å; I247-Y249 PolarHBondContact O-N 2.64Å; I247-A250 PolarHBondContact O-N 2.81Å; I247-F251 HydrophobicContact CB-CD2 4.48Å; I247-F251 HydrophobicContact CG2-CD2 3.41Å; I247-F251 VanDerWaalsContact CG2-CD2 3.41Å; I247-F251 HydrophobicContact CG2-CE2 3.69Å; I247-F251 HydrophobicContact CG2-CG 4.43Å; I247-F251 WeakPolarHBondContact O-CB 3.2Å; I247-F251 WeakPolarHBondContact O-CD2 3.32Å; I247-F251 PolarHBondContact O-N 3.38Å
248	G	95.2	Very high	94.3	Very high	0 Å²	0	43.9 Å²	43.9	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-56.9	-48.1	174.7	0	0	0	0	0	113.2	M89 L244 P245 L246 G252 T273	M89-G248 WeakPolarHBondContact SD-CA 3.43Å; L244-G248 PolarHBondContact O-N 3.32Å; L244-G248 VanDerWaalsContact O-N 3.11Å; P245-G248 CarbonylContact O-C 3.48Å; P245-G248 WeakPolarHBondContact O-CA 3.16Å; P245-G248 PolarHBondContact O-N 3.3Å; L246-G248 VanDerWaalsContact C-N 3.3Å; G248-G252 WeakPolarHBondContact O-CA 3.29Å; G248-G252 PolarHBondContact O-N 3.2Å; G248-T273 WeakPolarHBondContact O-CB 3.33Å; G248-T273 WeakPolarHBondContact O-CG2 3.36Å
249	Y	95.6	Very high	94.2	Very high	7 Å²	7	45.7 Å²	45.7	3%	0.027	23%	0.23	C	C	.	.	H	α-helix	trans	-61.7	-46.9	176	-63.6	-50.5	0	0	0	111.7	P245 L246 I247 Y253 A270 M271 C275 Q308 E311 L315	P245-Y249 HydrophobicContact CB-CD2 4.46Å; P245-Y249 HydrophobicContact CB-CE2 3.91Å; P245-Y249 WeakPolarHBondContact O-CD2 3.49Å; P245-Y249 PolarHBondContact O-N 3.29Å; L246-Y249 PolarHBondContact O-N 2.96Å; I247-Y249 PolarHBondContact O-N 2.64Å; Y249-Y253 PolarHBondContact O-N 3.22Å; Y249-Y253 VanDerWaalsContact O-N 3.1Å; Y249-A270 VanDerWaalsContact CD1-O 3.29Å; Y249-A270 WeakPolarHBondContact CD1-O 3.28Å; Y249-A270 WeakPolarHBondContact O-CB 3.34Å; Y249-M271 HydrophobicContact CD1-SD 4.34Å; Y249-M271 HydrophobicContact CE1-SD 4.09Å; Y249-C275 HydrophobicContact CE1-CB 4.5Å; Y249-Q308 VanDerWaalsContact OH-CG 3.24Å; Y249-Q308 WeakPolarHBondContact OH-CG 3.2Å; Y249-Q308 PolarHBondContact OH-O 3.02Å; Y249-E311 HydrophobicContact CD2-CB 4.39Å; Y249-E311 HydrophobicContact CE2-CB 3.92Å; Y249-L315 HydrophobicContact CD1-CD1 4.34Å; Y249-L315 HydrophobicContact CD2-CD1 3.86Å; Y249-L315 HydrophobicContact CE2-CD1 4.5Å; Y249-L315 HydrophobicContact CG-CD1 3.79Å
250	A	95.8	Very high	94	Very high	46 Å²	46	54.9 Å²	54.9	38%	0.38	26%	0.258	S	S	.	.	H	α-helix	trans	-65.3	-52.7	-177.9	0	0	0	0	0	112.1	L246 I247 G252 Y253 I254	L246-A250 WeakPolarHBondContact O-CB 3.44Å; L246-A250 PolarHBondContact O-N 3.16Å; I247-A250 PolarHBondContact O-N 2.81Å; A250-G252 PolarHBondContact O-N 3.44Å; A250-Y253 PolarHBondContact O-N 3.24Å; A250-I254 VanDerWaalsContact O-CG1 3.28Å; A250-I254 WeakPolarHBondContact O-CG1 3.28Å; A250-I254 PolarHBondContact O-N 3.41Å
251	F	94.4	Very high	93.7	Very high	102 Å²	102	55.7 Å²	55.7	45%	0.447	26%	0.262	S	S	.	.	H	α-helix	trans	-68.6	-34.9	-179.8	-85.2	-93.1	0	0	0	112.3	I88 I247 Y253 I254 I255	I88-F251 HydrophobicContact CD1-CB 3.94Å; I88-F251 HydrophobicContact CG2-CB 3.7Å; I88-F251 HydrophobicContact CG2-CD1 4.41Å; I88-F251 HydrophobicContact CG2-CG 4.03Å; I247-F251 HydrophobicContact CB-CD2 4.48Å; I247-F251 HydrophobicContact CG2-CD2 3.41Å; I247-F251 VanDerWaalsContact CG2-CD2 3.41Å; I247-F251 HydrophobicContact CG2-CE2 3.69Å; I247-F251 HydrophobicContact CG2-CG 4.43Å; I247-F251 WeakPolarHBondContact O-CB 3.2Å; I247-F251 WeakPolarHBondContact O-CD2 3.32Å; I247-F251 PolarHBondContact O-N 3.38Å; F251-Y253 VanDerWaalsContact C-N 3.27Å; F251-Y253 PolarHBondContact O-N 2.91Å; F251-I254 PolarHBondContact O-N 2.81Å; F251-I255 WeakPolarHBondContact O-CB 3.4Å; F251-I255 VanDerWaalsContact O-CG2 3.3Å; F251-I255 WeakPolarHBondContact O-CG2 3.37Å; F251-I255 PolarHBondContact O-N 3.17Å
252	G	93.6	Very high	93.6	Very high	0 Å²	0	59.4 Å²	59.4	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-58.6	-40.1	171.6	0	0	0	0	0	112	G248 A250 I255 S256 V269	G248-G252 WeakPolarHBondContact O-CA 3.29Å; G248-G252 PolarHBondContact O-N 3.2Å; A250-G252 PolarHBondContact O-N 3.44Å; G252-I255 WeakPolarHBondContact O-CG2 3.43Å; G252-S256 WeakPolarHBondContact O-CB 3.48Å; G252-S256 PolarHBondContact O-N 2.95Å; G252-S256 PolarHBondContact O-OG 2.88Å; G252-V269 VanDerWaalsContact O-CG1 3.31Å; G252-V269 WeakPolarHBondContact O-CG1 3.26Å
253	Y	93.9	Very high	93.4	Very high	84 Å²	84	61.9 Å²	61.9	33%	0.329	29%	0.294	S	S	.	.	H	α-helix	trans	-69.5	-44.2	173.8	-166.6	-90.8	0	0	0	112.6	Y249 A250 F251 S256 W257 Q263 R266 R267 A270	Y249-Y253 PolarHBondContact O-N 3.22Å; Y249-Y253 VanDerWaalsContact O-N 3.1Å; A250-Y253 PolarHBondContact O-N 3.24Å; F251-Y253 VanDerWaalsContact C-N 3.27Å; F251-Y253 PolarHBondContact O-N 2.91Å; Y253-S256 WeakPolarHBondContact CA-OG 3.32Å; Y253-S256 PolarHBondContact O-OG 3.02Å; Y253-W257 WeakPolarHBondContact O-CB 3.41Å; Y253-W257 PolarHBondContact O-N 2.92Å; Y253-Q263 PolarHBondContact OH-OE1 2.97Å; Y253-R266 HydrophobicContact CD2-CB 3.94Å; Y253-R266 HydrophobicContact CE2-CB 3.69Å; Y253-R267 HydrophobicContact CE2-CG 4.33Å; Y253-A270 HydrophobicContact CD2-CB 4.35Å
254	I	94.1	Very high	93.2	Very high	87 Å²	87	61.4 Å²	61.4	45%	0.446	29%	0.294	S	S	.	.	H	α-helix	trans	-64.1	-46.7	-178.7	-68	163.4	0	0	0	110.8	A250 F251 S256 W257 V258	A250-I254 VanDerWaalsContact O-CG1 3.28Å; A250-I254 WeakPolarHBondContact O-CG1 3.28Å; A250-I254 PolarHBondContact O-N 3.41Å; F251-I254 PolarHBondContact O-N 2.81Å; I254-S256 PolarHBondContact O-N 3.16Å; I254-W257 WeakPolarHBondContact O-CB 3.19Å; I254-W257 PolarHBondContact O-N 2.07Å; I254-W257 VanDerWaalsContact O-N 3.16Å; I254-V258 WeakPolarHBondContact O-CG2 3.49Å; I254-V258 PolarHBondContact O-N 3.33Å
255	I	92	Very high	93	Very high	26 Å²	26	63.2 Å²	63.2	13%	0.133	30%	0.302	C	S	.	.	H	α-helix	trans	-65.7	-42.8	-177.9	-158.5	160.7	0	0	0	110.7	I80 L83 I88 F251 G252 W257 V258 F259 V269	I80-I255 HydrophobicContact CG2-CG2 4.16Å; L83-I255 HydrophobicContact CD2-CD1 3.53Å; L83-I255 HydrophobicContact CD2-CG1 4.48Å; L83-I255 HydrophobicContact CG-CD1 3.73Å; I88-I255 HydrophobicContact CD1-CB 4.38Å; I88-I255 HydrophobicContact CD1-CD1 3.75Å; I88-I255 HydrophobicContact CD1-CG2 4.29Å; F251-I255 WeakPolarHBondContact O-CB 3.4Å; F251-I255 VanDerWaalsContact O-CG2 3.3Å; F251-I255 WeakPolarHBondContact O-CG2 3.37Å; F251-I255 PolarHBondContact O-N 3.17Å; G252-I255 WeakPolarHBondContact O-CG2 3.43Å; I255-W257 PolarHBondContact O-N 3.32Å; I255-V258 PolarHBondContact O-N 2.75Å; I255-V258 VanDerWaalsContact O-N 3.12Å; I255-F259 HydrophobicContact CD1-CE2 4.29Å; I255-F259 HydrophobicContact CG1-CD2 3.87Å; I255-F259 HydrophobicContact CG1-CE2 3.72Å; I255-F259 VanDerWaalsContact O-CD2 3.24Å; I255-F259 WeakPolarHBondContact O-CD2 3.17Å; I255-F259 PolarHBondContact O-N 3.11Å; I255-V269 HydrophobicContact CG2-CG1 4.38Å
256	S	91.4	Very high	92.9	Very high	0 Å²	0	65 Å²	65	0%	0	31%	0.309	C	S	.	.	H	α-helix	trans	-65.4	-29.7	176	57.4	0	0	0	0	112.7	G252 Y253 I254 R260 L261 R266	G252-S256 WeakPolarHBondContact O-CB 3.48Å; G252-S256 PolarHBondContact O-N 2.95Å; G252-S256 PolarHBondContact O-OG 2.88Å; Y253-S256 WeakPolarHBondContact CA-OG 3.32Å; Y253-S256 PolarHBondContact O-OG 3.02Å; I254-S256 PolarHBondContact O-N 3.16Å; S256-R260 PolarHBondContact O-N 2.89Å; S256-L261 VanDerWaalsContact O-CD1 3.28Å; S256-L261 WeakPolarHBondContact O-CD1 3.36Å; S256-L261 PolarHBondContact O-N 3.22Å; S256-L261 VanDerWaalsContact O-N 3.08Å; S256-R266 VanDerWaalsContact OG-CA 3.31Å; S256-R266 WeakPolarHBondContact OG-CA 3.43Å; S256-R266 WeakPolarHBondContact OG-CB 3.2Å
257	W	92.2	Very high	92.8	Very high	152 Å²	152	62.9 Å²	62.9	58%	0.576	30%	0.296	S	S	*	.	H	α-helix	trans	-66.4	-45.7	169.4	175.4	86	0	0	0	112.5	Y253 I254 I255 F259 R260	Y253-W257 WeakPolarHBondContact O-CB 3.41Å; Y253-W257 PolarHBondContact O-N 2.92Å; I254-W257 WeakPolarHBondContact O-CB 3.19Å; I254-W257 PolarHBondContact O-N 2.07Å; I254-W257 VanDerWaalsContact O-N 3.16Å; I255-W257 PolarHBondContact O-N 3.32Å; W257-F259 VanDerWaalsContact C-N 3.31Å; W257-F259 PolarHBondContact O-N 3.22Å; W257-R260 WeakPolarHBondContact O-CA 3.46Å; W257-R260 PolarHBondContact O-N 3.18Å
258	V	92.3	Very high	92.7	Very high	88 Å²	88	61 Å²	61	53%	0.533	29%	0.286	S	S	.	.	H	α-helix	trans	-59.1	-41.8	176.8	172	0	0	0	0	111.4	I254 I255 R260	I254-V258 WeakPolarHBondContact O-CG2 3.49Å; I254-V258 PolarHBondContact O-N 3.33Å; I255-V258 PolarHBondContact O-N 2.75Å; I255-V258 VanDerWaalsContact O-N 3.12Å; V258-R260 PolarHBondContact O-N 2.88Å
259	F	89.1	Confident	92.6	Very high	111 Å²	111	61 Å²	61	49%	0.487	29%	0.286	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77	5.6	175.7	-77.2	-78.8	0	0	0	114.2	I80 L83 I255 W257 L261	I80-F259 HydrophobicContact CD1-CB 3.41Å; I80-F259 VanDerWaalsContact CD1-CB 3.41Å; I80-F259 HydrophobicContact CD1-CD1 4.15Å; I80-F259 HydrophobicContact CD1-CD2 3.94Å; I80-F259 HydrophobicContact CD1-CG 3.58Å; I80-F259 HydrophobicContact CG1-CB 4.23Å; I80-F259 HydrophobicContact CG1-CD1 4.27Å; I80-F259 HydrophobicContact CG1-CD2 3.8Å; I80-F259 HydrophobicContact CG1-CE2 4.24Å; I80-F259 HydrophobicContact CG1-CG 3.84Å; L83-F259 HydrophobicContact CD2-CE2 4.02Å; L83-F259 HydrophobicContact CD2-CZ 4.18Å; I255-F259 HydrophobicContact CD1-CE2 4.29Å; I255-F259 HydrophobicContact CG1-CD2 3.87Å; I255-F259 HydrophobicContact CG1-CE2 3.72Å; I255-F259 VanDerWaalsContact O-CD2 3.24Å; I255-F259 WeakPolarHBondContact O-CD2 3.17Å; I255-F259 PolarHBondContact O-N 3.11Å; W257-F259 VanDerWaalsContact C-N 3.31Å; W257-F259 PolarHBondContact O-N 3.22Å; F259-L261 VanDerWaalsContact C-N 3.32Å; F259-L261 HydrophobicContact CB-CD1 3.88Å; F259-L261 PolarHBondContact O-N 2.94Å
260	R	89.8	Confident	92.5	Very high	223 Å²	223	61.1 Å²	61.1	84%	0.842	29%	0.288	S	S	*	.	T	Hydrogen-bonded Turn	trans	58.5	34.3	174.9	-53.5	-177.4	179.3	-174.4	-0.8	114.3	S256 W257 V258	S256-R260 PolarHBondContact O-N 2.89Å; W257-R260 WeakPolarHBondContact O-CA 3.46Å; W257-R260 PolarHBondContact O-N 3.18Å; V258-R260 PolarHBondContact O-N 2.88Å
261	L	89.4	Confident	92.5	Very high	17 Å²	17	59 Å²	59	9%	0.089	27%	0.271	C	S	.	.			trans	-66.3	163.7	170.9	-68.5	106.8	0	0	0	111.6	I80 L135 S256 F259 E265 R266	I80-L261 HydrophobicContact CD1-CD1 3.22Å; I80-L261 HydrophobicContact CD1-CD2 4.41Å; I80-L261 HydrophobicContact CD1-CG 4.23Å; L135-L261 HydrophobicContact CD2-CD2 4.31Å; S256-L261 VanDerWaalsContact O-CD1 3.28Å; S256-L261 WeakPolarHBondContact O-CD1 3.36Å; S256-L261 PolarHBondContact O-N 3.22Å; S256-L261 VanDerWaalsContact O-N 3.08Å; F259-L261 VanDerWaalsContact C-N 3.32Å; F259-L261 HydrophobicContact CB-CD1 3.88Å; F259-L261 PolarHBondContact O-N 2.94Å; L261-E265 HydrophobicContact CB-CB 3.78Å; L261-E265 HydrophobicContact CD2-CB 3.67Å; L261-E265 HydrophobicContact CD2-CG 4.22Å; L261-E265 HydrophobicContact CG-CB 4.34Å; L261-R266 HydrophobicContact CB-CG 4.19Å; L261-R266 PolarHBondContact O-NE 3.32Å; L261-R266 PolarHBondContact O-NH2 2.93Å
262	T	91.5	Very high	92.4	Very high	78 Å²	78	54.2 Å²	54.2	48%	0.479	25%	0.25	S	C	.	.			trans	-69.5	162.2	174.4	65.6	0	0	0	0	111.8	E265 R266	T262-E265 WeakPolarHBondContact CB-OE2 3.32Å; T262-E265 WeakPolarHBondContact CG2-OE2 3.25Å; T262-E265 PolarHBondContact N-OE2 3.07Å; T262-E265 PolarHBondContact O-N 2.94Å; T262-E265 VanDerWaalsContact O-N 3.16Å; T262-E265 WeakPolarHBondContact OG1-CG 3.46Å; T262-E265 PolarHBondContact OG1-OE2 3.45Å; T262-R266 WeakPolarHBondContact O-CG 3.29Å; T262-R266 PolarHBondContact O-N 3.43Å
263	Q	92.1	Very high	92.3	Very high	100 Å²	100	54.2 Å²	54.2	47%	0.467	25%	0.25	S	C	.	.	H	α-helix	trans	-58.4	-40.9	-179.8	-73.1	-70	3.2	0	0	114.4	Y253 R267	Y253-Q263 PolarHBondContact OH-OE1 2.97Å; Q263-R267 WeakPolarHBondContact O-CG 3.44Å; Q263-R267 PolarHBondContact O-N 3.45Å; Q263-R267 PolarHBondContact O-NE 3.26Å
264	P	91.8	Very high	92.2	Very high	48 Å²	48	50.2 Å²	50.2	31%	0.312	23%	0.234	S	C	.	.	H	α-helix	trans	-60.1	-45.3	171	-22	33.4	0	0	0	113.2	G131 D132 R267 T268	G131-P264 WeakPolarHBondContact CA-O 3.28Å; D132-P264 PolarHBondContact N-O 2.82Å; P264-R267 VanDerWaalsContact CA-NH2 3.28Å; P264-R267 PolarHBondContact O-N 2.88Å; P264-T268 PolarHBondContact O-N 3.04Å; P264-T268 PolarHBondContact O-OG1 3.49Å
265	E	91.2	Very high	92.2	Very high	39 Å²	39	46.1 Å²	46.1	18%	0.182	21%	0.213	C	C	.	.	H	α-helix	trans	-66.5	-39.5	-179.2	-67.9	170	135.9	0	0	112.2	D132 L135 L261 T262 R267 T268 V269	D132-E265 HydrophobicContact CB-CG 4.22Å; L135-E265 HydrophobicContact CD2-CB 3.7Å; L135-E265 HydrophobicContact CD2-CG 3.8Å; L261-E265 HydrophobicContact CB-CB 3.78Å; L261-E265 HydrophobicContact CD2-CB 3.67Å; L261-E265 HydrophobicContact CD2-CG 4.22Å; L261-E265 HydrophobicContact CG-CB 4.34Å; T262-E265 WeakPolarHBondContact CB-OE2 3.32Å; T262-E265 WeakPolarHBondContact CG2-OE2 3.25Å; T262-E265 PolarHBondContact N-OE2 3.07Å; T262-E265 PolarHBondContact O-N 2.94Å; T262-E265 VanDerWaalsContact O-N 3.16Å; T262-E265 WeakPolarHBondContact OG1-CG 3.46Å; T262-E265 PolarHBondContact OG1-OE2 3.45Å; E265-R267 VanDerWaalsContact C-N 3.34Å; E265-R267 PolarHBondContact O-N 3.14Å; E265-T268 WeakPolarHBondContact O-CB 3.4Å; E265-T268 PolarHBondContact O-N 3.17Å; E265-V269 WeakPolarHBondContact O-CG2 3.33Å; E265-V269 PolarHBondContact O-N 3.19Å
266	R	93.2	Very high	92.2	Very high	39 Å²	39	45.1 Å²	45.1	15%	0.147	21%	0.207	C	C	.	.	H	α-helix	trans	-60.2	-42.9	176.1	-68.2	175.2	-165.8	166.1	1.5	112.7	Y253 S256 L261 T262 T268 V269 A270	Y253-R266 HydrophobicContact CD2-CB 3.94Å; Y253-R266 HydrophobicContact CE2-CB 3.69Å; S256-R266 VanDerWaalsContact OG-CA 3.31Å; S256-R266 WeakPolarHBondContact OG-CA 3.43Å; S256-R266 WeakPolarHBondContact OG-CB 3.2Å; L261-R266 HydrophobicContact CB-CG 4.19Å; L261-R266 PolarHBondContact O-NE 3.32Å; L261-R266 PolarHBondContact O-NH2 2.93Å; T262-R266 WeakPolarHBondContact O-CG 3.29Å; T262-R266 PolarHBondContact O-N 3.43Å; R266-T268 VanDerWaalsContact C-N 3.32Å; R266-V269 PolarHBondContact O-N 3.03Å; R266-A270 WeakPolarHBondContact O-CB 3.39Å; R266-A270 PolarHBondContact O-N 3.47Å
267	R	94.1	Very high	92.1	Very high	35 Å²	35	46.4 Å²	46.4	13%	0.132	21%	0.214	C	C	.	.	H	α-helix	trans	-65.1	-38.6	176.3	-70.3	175	-69.5	169	2	111.3	I129 K130 Y253 Q263 P264 E265 M271	I129-R267 HydrophobicContact CG2-CB 3.88Å; I129-R267 PolarHBondContact O-NH1 3.44Å; K130-R267 PolarHBondContact O-NH1 3.03Å; K130-R267 PolarHBondContact O-NH2 3.2Å; Y253-R267 HydrophobicContact CE2-CG 4.33Å; Q263-R267 WeakPolarHBondContact O-CG 3.44Å; Q263-R267 PolarHBondContact O-N 3.45Å; Q263-R267 PolarHBondContact O-NE 3.26Å; P264-R267 VanDerWaalsContact CA-NH2 3.28Å; P264-R267 PolarHBondContact O-N 2.88Å; E265-R267 VanDerWaalsContact C-N 3.34Å; E265-R267 PolarHBondContact O-N 3.14Å; R267-M271 WeakPolarHBondContact O-CG 3.45Å; R267-M271 PolarHBondContact O-N 3.37Å
268	T	93.3	Very high	91.8	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-61	-51.5	172.6	-63.1	0	0	0	0	111.5	A126 D132 L135 M139 P264 E265 R266 A270 M271 E272	A126-T268 HydrophobicContact CB-CG2 4.34Å; D132-T268 WeakPolarHBondContact CA-OG1 3.34Å; D132-T268 PolarHBondContact N-OG1 3.3Å; D132-T268 VanDerWaalsContact O-CG2 3.26Å; D132-T268 WeakPolarHBondContact O-CG2 3.41Å; D132-T268 PolarHBondContact O-OG1 3.42Å; L135-T268 HydrophobicContact CB-CG2 4.09Å; L135-T268 HydrophobicContact CD2-CG2 4.23Å; L135-T268 HydrophobicContact CG-CG2 4.06Å; M139-T268 HydrophobicContact SD-CG2 4.41Å; P264-T268 PolarHBondContact O-N 3.04Å; P264-T268 PolarHBondContact O-OG1 3.49Å; E265-T268 WeakPolarHBondContact O-CB 3.4Å; E265-T268 PolarHBondContact O-N 3.17Å; R266-T268 VanDerWaalsContact C-N 3.32Å; T268-A270 VanDerWaalsContact C-N 3.27Å; T268-A270 PolarHBondContact O-N 3.27Å; T268-M271 PolarHBondContact O-N 3.39Å; T268-E272 WeakPolarHBondContact O-CB 3.42Å; T268-E272 PolarHBondContact O-N 2.76Å
269	V	93.3	Very high	91.2	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-61	-38.9	-178.9	176.4	0	0	0	0	111.3	I80 L135 M139 G252 I255 E265 R266 T273	I80-V269 HydrophobicContact CG2-CG1 3.87Å; I80-V269 HydrophobicContact CG2-CG2 4.33Å; L135-V269 HydrophobicContact CD2-CG2 4.21Å; M139-V269 HydrophobicContact CE-CB 4.16Å; M139-V269 HydrophobicContact CE-CG1 3.98Å; M139-V269 HydrophobicContact CE-CG2 3.86Å; M139-V269 HydrophobicContact SD-CB 4.49Å; M139-V269 HydrophobicContact SD-CG2 3.81Å; G252-V269 VanDerWaalsContact O-CG1 3.31Å; G252-V269 WeakPolarHBondContact O-CG1 3.26Å; I255-V269 HydrophobicContact CG2-CG1 4.38Å; E265-V269 WeakPolarHBondContact O-CG2 3.33Å; E265-V269 PolarHBondContact O-N 3.19Å; R266-V269 PolarHBondContact O-N 3.03Å; V269-T273 WeakPolarHBondContact O-CB 3.38Å; V269-T273 PolarHBondContact O-N 3.07Å; V269-T273 PolarHBondContact O-OG1 3.31Å
270	A	94.7	Very high	90.6	Very high	8 Å²	8	34.8 Å²	34.8	7%	0.066	16%	0.163	C	C	.	.	H	α-helix	trans	-57.9	-56.6	173.2	0	0	0	0	0	111.3	Y249 Y253 R266 T268 E272 T273 G274	Y249-A270 VanDerWaalsContact CD1-O 3.29Å; Y249-A270 WeakPolarHBondContact CD1-O 3.28Å; Y249-A270 WeakPolarHBondContact O-CB 3.34Å; Y253-A270 HydrophobicContact CD2-CB 4.35Å; R266-A270 WeakPolarHBondContact O-CB 3.39Å; R266-A270 PolarHBondContact O-N 3.47Å; T268-A270 VanDerWaalsContact C-N 3.27Å; T268-A270 PolarHBondContact O-N 3.27Å; A270-E272 VanDerWaalsContact C-N 3.29Å; A270-E272 PolarHBondContact O-N 2.82Å; A270-T273 PolarHBondContact O-N 3.37Å; A270-G274 PolarHBondContact O-N 3.43Å; A270-G274 VanDerWaalsContact O-N 3.09Å
271	M	94.3	Very high	90.4	Very high	3 Å²	3	24.2 Å²	24.2	2%	0.015	12%	0.123	C	C	.	.	H	α-helix	trans	-59.7	-39.9	-179.6	-70.2	-62.1	166.9	0	0	112.2	L125 I129 Y249 R267 T268 C275 A312 L315 I316	L125-M271 HydrophobicContact CB-CB 4.36Å; L125-M271 HydrophobicContact CB-CG 4.22Å; L125-M271 HydrophobicContact CB-SD 3.92Å; I129-M271 HydrophobicContact CB-CE 4.33Å; I129-M271 HydrophobicContact CD1-CE 3.5Å; I129-M271 HydrophobicContact CG1-CE 4.48Å; I129-M271 HydrophobicContact CG2-CE 4.25Å; I129-M271 HydrophobicContact CG2-CG 4.15Å; Y249-M271 HydrophobicContact CD1-SD 4.34Å; Y249-M271 HydrophobicContact CE1-SD 4.09Å; R267-M271 WeakPolarHBondContact O-CG 3.45Å; R267-M271 PolarHBondContact O-N 3.37Å; T268-M271 PolarHBondContact O-N 3.39Å; M271-C275 WeakPolarHBondContact O-CB 3.44Å; M271-C275 PolarHBondContact O-N 3.47Å; M271-A312 HydrophobicContact SD-CB 4.42Å; M271-L315 HydrophobicContact CE-CB 3.95Å; M271-L315 HydrophobicContact CE-CD1 4.17Å; M271-I316 HydrophobicContact CE-CG1 4.42Å
272	E	92.5	Very high	90	Very high	1 Å²	1	23.6 Å²	23.6	1%	0.005	12%	0.121	C	C	.	.	H	α-helix	trans	-64.5	-44	177.8	-168.6	68.5	-161.8	0	0	112.2	Q85 S122 S136 M139 T140 T268 A270	Q85-E272 PolarHBondContact OE1-O 3.45Å; S122-E272 WeakPolarHBondContact CB-OE2 3.45Å; S122-E272 PolarHBondContact OG-OE2 3.46Å; S136-E272 PolarHBondContact OG-OE2 2.95Å; M139-E272 HydrophobicContact CB-CG 3.65Å; M139-E272 HydrophobicContact CE-CB 3.96Å; M139-E272 HydrophobicContact CE-CG 3.83Å; M139-E272 HydrophobicContact SD-CB 4.22Å; M139-E272 HydrophobicContact SD-CG 4.15Å; T140-E272 WeakPolarHBondContact CA-OE1 3.34Å; T140-E272 VanDerWaalsContact CB-OE1 3.29Å; T140-E272 WeakPolarHBondContact CB-OE1 3.23Å; T140-E272 PolarHBondContact N-OE1 3.29Å; T140-E272 VanDerWaalsContact OG1-CD 3.22Å; T140-E272 PolarHBondContact OG1-OE1 2.88Å; T140-E272 PolarHBondContact OG1-OE2 3.28Å; T140-E272 VanDerWaalsContact OG1-OE2 3.13Å; T268-E272 WeakPolarHBondContact O-CB 3.42Å; T268-E272 PolarHBondContact O-N 2.76Å; A270-E272 VanDerWaalsContact C-N 3.29Å; A270-E272 PolarHBondContact O-N 2.82Å
273	T	93.2	Very high	89.1	Confident	0 Å²	0	20 Å²	20	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-71	-44.1	-175.1	-54.4	0	0	0	0	111.8	S84 M89 G248 V269 A270 Q276	S84-T273 VanDerWaalsContact CB-OG1 3.24Å; S84-T273 WeakPolarHBondContact CB-OG1 3.36Å; S84-T273 PolarHBondContact OG-OG1 3.25Å; M89-T273 WeakPolarHBondContact CE-O 3.16Å; M89-T273 HydrophobicContact CG-CG2 3.87Å; M89-T273 WeakPolarHBondContact CG-O 3.48Å; M89-T273 HydrophobicContact SD-CG2 4.24Å; G248-T273 WeakPolarHBondContact O-CB 3.33Å; G248-T273 WeakPolarHBondContact O-CG2 3.36Å; V269-T273 WeakPolarHBondContact O-CB 3.38Å; V269-T273 PolarHBondContact O-N 3.07Å; V269-T273 PolarHBondContact O-OG1 3.31Å; A270-T273 PolarHBondContact O-N 3.37Å; T273-Q276 PolarHBondContact O-NE2 3.37Å
274	G	91.7	Very high	88.4	Confident	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-78.2	-22.4	179.5	0	0	0	0	0	113.9	A270 Q276 Q308	A270-G274 PolarHBondContact O-N 3.43Å; A270-G274 VanDerWaalsContact O-N 3.09Å; G274-Q276 PolarHBondContact O-N 2.93Å; G274-Q308 PolarHBondContact O-OE1 2.87Å
275	C	92.8	Very high	87.7	Confident	0 Å²	0	13.1 Å²	13.1	0%	0	6%	0.062	C	C	.	.			trans	-92.2	91.8	-178.7	-171.2	0	0	0	0	111.7	G118 G119 S122 L125 Y249 M271 Q308	G118-C275 WeakPolarHBondContact CA-O 3.32Å; G119-C275 PolarHBondContact N-O 3.38Å; S122-C275 PolarHBondContact N-SG 3.11Å; S122-C275 VanDerWaalsContact N-SG 3.37Å; L125-C275 HydrophobicContact CD1-CB 4.27Å; Y249-C275 HydrophobicContact CE1-CB 4.5Å; M271-C275 WeakPolarHBondContact O-CB 3.44Å; M271-C275 PolarHBondContact O-N 3.47Å; C275-Q308 VanDerWaalsContact CA-CD 3.48Å; C275-Q308 PolarHBondContact SG-NE2 2.88Å
276	Q	91.6	Very high	86.8	Confident	5 Å²	5	12.6 Å²	12.6	2%	0.023	6%	0.06	C	C	.	.	B	Isolated β-bridge	trans	-77.4	154.5	178.8	-65.5	-63.8	-24.5	0	0	112.8	Q85 M89 C116 P117 T273 G274 I278 Q308	Q85-Q276 VanDerWaalsContact NE2-CD 3.28Å; M89-Q276 HydrophobicContact CE-CG 3.69Å; C116-Q276 PolarHBondContact O-OE1 3.27Å; P117-Q276 PolarHBondContact O-OE1 3.22Å; T273-Q276 PolarHBondContact O-NE2 3.37Å; G274-Q276 PolarHBondContact O-N 2.93Å; Q276-I278 HydrophobicContact CB-CD1 4.44Å; Q276-I278 PolarHBondContact O-N 3.32Å; Q276-Q308 VanDerWaalsContact N-CD 3.32Å; Q276-Q308 PolarHBondContact O-NE2 3.48Å; Q276-Q308 VanDerWaalsContact O-NE2 3.16Å
277	N	89.3	Confident	85.6	Confident	27 Å²	27	12.4 Å²	12.4	14%	0.144	6%	0.063	C	C	.	.			trans	-75.7	88.4	171.5	-168.2	-28.2	0	0	0	111.1	P117 Q279 L280 C281	P117-N277 HydrophobicContact CG-CB 4.38Å; P117-N277 WeakPolarHBondContact O-CB 3.5Å; P117-N277 PolarHBondContact O-N 3.22Å; N277-Q279 VanDerWaalsContact C-N 3.27Å; N277-Q279 PolarHBondContact O-N 3.46Å; N277-Q279 PolarHBondContact OD1-N 3.3Å; N277-L280 HydrophobicContact CB-CB 3.94Å; N277-L280 PolarHBondContact O-N 3.08Å; N277-L280 PolarHBondContact OD1-N 3.02Å; N277-C281 PolarHBondContact O-N 3.36Å
278	I	87.3	Confident	84.4	Confident	31 Å²	31	11.9 Å²	11.9	16%	0.159	7%	0.066	C	C	.	.	H	α-helix	trans	-59.8	-37.5	-179.1	-56.9	-53.9	0	0	0	112.4	Q276 C281 A282 P301 L304	Q276-I278 HydrophobicContact CB-CD1 4.44Å; Q276-I278 PolarHBondContact O-N 3.32Å; I278-C281 PolarHBondContact O-N 3.17Å; I278-A282 WeakPolarHBondContact O-CB 3.37Å; I278-A282 PolarHBondContact O-N 3Å; I278-P301 HydrophobicContact CG2-CB 4.2Å; I278-P301 WeakPolarHBondContact CG2-O 3.27Å; I278-L304 HydrophobicContact CD1-CB 4.49Å; I278-L304 HydrophobicContact CD1-CD2 4.14Å; I278-L304 HydrophobicContact CD1-CG 4.29Å
279	Q	78.3	Confident	83.3	Confident	64 Å²	64	13 Å²	13	30%	0.299	7%	0.071	S	C	.	.	H	α-helix	trans	-63.3	-45	177.6	-177.6	-177.9	-23.3	0	0	110.7	L210 N277 T283	L210-Q279 HydrophobicContact CD2-CG 4.07Å; N277-Q279 VanDerWaalsContact C-N 3.27Å; N277-Q279 PolarHBondContact O-N 3.46Å; N277-Q279 PolarHBondContact OD1-N 3.3Å; Q279-T283 WeakPolarHBondContact O-CB 3.48Å; Q279-T283 PolarHBondContact O-N 2.92Å; Q279-T283 PolarHBondContact O-OG1 3.48Å
280	L	78.3	Confident	82	Confident	13 Å²	13	16.7 Å²	16.7	7%	0.068	10%	0.095	C	C	.	.	H	α-helix	trans	-61.4	-48.3	173.9	178	69.3	0	0	0	111	L59 C116 P117 M151 N277 A282 T283 V284	L59-L280 HydrophobicContact CD1-CB 4.11Å; L59-L280 HydrophobicContact CD1-CD1 3.41Å; L59-L280 VanDerWaalsContact CD1-CD1 3.41Å; L59-L280 HydrophobicContact CD1-CG 4.35Å; L59-L280 HydrophobicContact CD2-CD1 3.11Å; L59-L280 HydrophobicContact CG-CD1 3.73Å; C116-L280 HydrophobicContact CB-CD2 4.41Å; P117-L280 HydrophobicContact CG-CD2 3.67Å; M151-L280 HydrophobicContact SD-CD2 4.07Å; N277-L280 HydrophobicContact CB-CB 3.94Å; N277-L280 PolarHBondContact O-N 3.08Å; N277-L280 PolarHBondContact OD1-N 3.02Å; L280-A282 PolarHBondContact O-N 3.06Å; L280-T283 PolarHBondContact O-N 3.11Å; L280-V284 HydrophobicContact CD1-CG2 3.78Å; L280-V284 HydrophobicContact CG-CG2 4.15Å; L280-V284 WeakPolarHBondContact O-CG2 3.11Å; L280-V284 PolarHBondContact O-N 2.57Å
281	C	84.7	Confident	80.6	Confident	0 Å²	0	19 Å²	19	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-56.8	-50.9	-179.5	-173.1	0	0	0	0	110.7	C113 C116 N277 I278 T283 V284 V285 P301	C113-C281 WeakPolarHBondContact CA-SG 3.36Å; C113-C281 HydrophobicContact CB-CB 4.24Å; C113-C281 WeakPolarHBondContact CB-SG 3.27Å; C113-C281 PolarHBondContact N-SG 3.32Å; C113-C281 VanDerWaalsContact N-SG 3.41Å; C113-C281 WeakPolarHBondContact SG-CB 3.31Å; C113-C281 CovalentContact SG-SG 2.07Å; C113-C281 PolarHBondContact SG-SG 3.1Å; C116-C281 VanDerWaalsContact SG-CA 3.55Å; C116-C281 VanDerWaalsContact SG-CB 3.54Å; N277-C281 PolarHBondContact O-N 3.36Å; I278-C281 PolarHBondContact O-N 3.17Å; C281-T283 VanDerWaalsContact C-N 3.32Å; C281-T283 PolarHBondContact O-N 3.24Å; C281-V284 PolarHBondContact O-N 2.99Å; C281-V285 VanDerWaalsContact O-CG2 3.29Å; C281-V285 WeakPolarHBondContact O-CG2 3.38Å; C281-V285 PolarHBondContact O-N 3.5Å; C281-P301 HydrophobicContact CB-CB 4.13Å; C281-P301 HydrophobicContact CB-CG 4.3Å
282	A	80.3	Confident	79.1	Confident	4 Å²	4	23.6 Å²	23.6	3%	0.033	15%	0.148	C	C	.	.	H	α-helix	trans	-60.1	-41.1	179.9	0	0	0	0	0	112.8	I278 L280 K286 P301	I278-A282 WeakPolarHBondContact O-CB 3.37Å; I278-A282 PolarHBondContact O-N 3Å; L280-A282 PolarHBondContact O-N 3.06Å; A282-K286 VanDerWaalsContact O-CG 3.31Å; A282-K286 WeakPolarHBondContact O-CG 3.4Å; A282-K286 PolarHBondContact O-N 3.19Å; A282-P301 HydrophobicContact CB-CB 4.08Å; A282-P301 HydrophobicContact CB-CG 4.32Å
283	T	74.3	Confident	77.8	Confident	2 Å²	2	27.5 Å²	27.5	1%	0.012	17%	0.171	C	C	.	.	H	α-helix	trans	-61.5	-50.2	174.7	-77.4	0	0	0	0	111.5	V55 M56 L59 L210 Q279 L280 C281 K286 V287	V55-T283 HydrophobicContact CG1-CG2 3.34Å; M56-T283 HydrophobicContact CE-CG2 3.44Å; M56-T283 VanDerWaalsContact CE-CG2 3.44Å; M56-T283 HydrophobicContact SD-CG2 3.89Å; L59-T283 HydrophobicContact CD2-CG2 4.25Å; L210-T283 WeakPolarHBondContact CD2-OG1 3.33Å; Q279-T283 WeakPolarHBondContact O-CB 3.48Å; Q279-T283 PolarHBondContact O-N 2.92Å; Q279-T283 PolarHBondContact O-OG1 3.48Å; L280-T283 PolarHBondContact O-N 3.11Å; C281-T283 VanDerWaalsContact C-N 3.32Å; C281-T283 PolarHBondContact O-N 3.24Å; T283-K286 PolarHBondContact O-N 2.97Å; T283-V287 WeakPolarHBondContact O-CB 3.29Å; T283-V287 VanDerWaalsContact O-CG2 3.28Å; T283-V287 WeakPolarHBondContact O-CG2 3.31Å; T283-V287 PolarHBondContact O-N 3.47Å
284	V	75.4	Confident	76.6	Confident	4 Å²	4	28 Å²	28	2%	0.024	17%	0.174	C	C	.	.	H	α-helix	trans	-66.2	-42.5	-177.1	174.6	0	0	0	0	111.2	M56 I112 M151 L280 C281 K286 V287 A288	M56-V284 HydrophobicContact CE-CG2 4.35Å; I112-V284 HydrophobicContact CD1-CG1 4.22Å; I112-V284 HydrophobicContact CG1-CG1 4.38Å; I112-V284 HydrophobicContact CG2-CB 3.94Å; I112-V284 HydrophobicContact CG2-CG1 3.77Å; M151-V284 HydrophobicContact CE-CB 4.06Å; M151-V284 HydrophobicContact CE-CG1 3.87Å; M151-V284 HydrophobicContact CE-CG2 3.92Å; M151-V284 HydrophobicContact SD-CG2 4.29Å; L280-V284 HydrophobicContact CD1-CG2 3.78Å; L280-V284 HydrophobicContact CG-CG2 4.15Å; L280-V284 WeakPolarHBondContact O-CG2 3.11Å; L280-V284 PolarHBondContact O-N 2.57Å; C281-V284 PolarHBondContact O-N 2.99Å; V284-K286 PolarHBondContact O-N 3.31Å; V284-V287 PolarHBondContact O-N 3.19Å; V284-A288 WeakPolarHBondContact O-CB 3.38Å; V284-A288 PolarHBondContact O-N 3.33Å
285	V	77.9	Confident	75.8	Confident	0 Å²	0	29.3 Å²	29.3	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-58.4	-47.9	178.1	170	0	0	0	0	111.5	V109 I112 C281 V287 F289 I294 P301	V109-V285 HydrophobicContact CG1-CG1 4.28Å; V109-V285 HydrophobicContact CG1-CG2 3.9Å; V109-V285 HydrophobicContact CG2-CG1 4.02Å; V109-V285 HydrophobicContact CG2-CG2 4.42Å; I112-V285 HydrophobicContact CB-CG2 4.27Å; I112-V285 HydrophobicContact CD1-CG2 4.17Å; I112-V285 HydrophobicContact CG2-CG2 3.84Å; C281-V285 VanDerWaalsContact O-CG2 3.29Å; C281-V285 WeakPolarHBondContact O-CG2 3.38Å; C281-V285 PolarHBondContact O-N 3.5Å; V285-V287 PolarHBondContact O-N 3.45Å; V285-F289 WeakPolarHBondContact O-CD2 3.36Å; V285-F289 PolarHBondContact O-N 3.06Å; V285-I294 HydrophobicContact CG1-CD1 3.83Å; V285-P301 HydrophobicContact CG2-CG 4.34Å
286	K	73	Confident	75	Confident	29 Å²	29	30.6 Å²	30.6	13%	0.126	20%	0.196	C	C	.	.	H	α-helix	trans	-62.8	-30.2	179.8	-78.9	177.6	169.1	-170.9	0	114.1	L210 I214 A282 T283 V284	L210-K286 HydrophobicContact CD1-CD 3.76Å; L210-K286 PolarHBondContact O-NZ 3.21Å; I214-K286 VanDerWaalsContact CA-NZ 3.31Å; A282-K286 VanDerWaalsContact O-CG 3.31Å; A282-K286 WeakPolarHBondContact O-CG 3.4Å; A282-K286 PolarHBondContact O-N 3.19Å; T283-K286 PolarHBondContact O-N 2.97Å; V284-K286 PolarHBondContact O-N 3.31Å
287	V	67.9	Low	74.5	Confident	34 Å²	34	30.8 Å²	30.8	21%	0.206	20%	0.197	C	C	.	.	H	α-helix	trans	-90.6	-41.2	-172.7	153.2	0	0	0	0	111.3	L52 M56 I181 T283 V284 V285 F289	L52-V287 HydrophobicContact CB-CG2 4.45Å; L52-V287 HydrophobicContact CD1-CB 3.68Å; L52-V287 HydrophobicContact CD1-CG1 3.01Å; L52-V287 HydrophobicContact CD1-CG2 3.33Å; L52-V287 HydrophobicContact CD2-CG1 4.4Å; L52-V287 HydrophobicContact CG-CG1 4.29Å; L52-V287 HydrophobicContact CG-CG2 4.49Å; M56-V287 HydrophobicContact CE-CB 3.64Å; M56-V287 HydrophobicContact CE-CG1 3.52Å; M56-V287 HydrophobicContact CE-CG2 3.71Å; I181-V287 HydrophobicContact CD1-CG1 3.61Å; I181-V287 HydrophobicContact CG1-CG1 3.49Å; I181-V287 VanDerWaalsContact CG1-CG1 3.49Å; T283-V287 WeakPolarHBondContact O-CB 3.29Å; T283-V287 VanDerWaalsContact O-CG2 3.28Å; T283-V287 WeakPolarHBondContact O-CG2 3.31Å; T283-V287 PolarHBondContact O-N 3.47Å; V284-V287 PolarHBondContact O-N 3.19Å; V285-V287 PolarHBondContact O-N 3.45Å; V287-F289 PolarHBondContact O-N 2.99Å
288	A	69.4	Low	74	Confident	25 Å²	25	29.8 Å²	29.8	21%	0.207	19%	0.191	C	C	.	.	H	α-helix	trans	-69.6	-23.8	-178.2	0	0	0	0	0	112	I181 V284	I181-A288 HydrophobicContact CD1-CB 4.46Å; V284-A288 WeakPolarHBondContact O-CB 3.38Å; V284-A288 PolarHBondContact O-N 3.33Å
289	F	69.6	Low	73.6	Confident	24 Å²	24	29.4 Å²	29.4	11%	0.105	19%	0.189	C	C	.	.	S	Bend	trans	-128.6	137.2	-173.7	-60.7	-75.1	0	0	0	113.4	V108 I112 V285 V287 V293 I294	V108-F289 HydrophobicContact CB-CZ 4.04Å; V108-F289 HydrophobicContact CG1-CE2 4.04Å; V108-F289 HydrophobicContact CG1-CZ 3.49Å; V108-F289 VanDerWaalsContact CG1-CZ 3.49Å; I112-F289 HydrophobicContact CD1-CD2 4.46Å; I112-F289 HydrophobicContact CD1-CE2 3.58Å; I112-F289 HydrophobicContact CD1-CZ 4.43Å; V285-F289 WeakPolarHBondContact O-CD2 3.36Å; V285-F289 PolarHBondContact O-N 3.06Å; V287-F289 PolarHBondContact O-N 2.99Å; F289-V293 HydrophobicContact CD1-CG1 4.48Å; F289-I294 HydrophobicContact CB-CB 4.2Å; F289-I294 HydrophobicContact CB-CD1 3.97Å; F289-I294 HydrophobicContact CB-CG1 3.83Å; F289-I294 HydrophobicContact CB-CG2 3.36Å; F289-I294 HydrophobicContact CD1-CG2 4.11Å; F289-I294 HydrophobicContact CD2-CG2 3.73Å; F289-I294 HydrophobicContact CG-CG2 3.45Å; F289-I294 VanDerWaalsContact CG-CG2 3.45Å
290	P	65.8	Low	74	Confident	76 Å²	76	26.5 Å²	26.5	49%	0.494	18%	0.176	S	C	.	.			trans	-59.5	141.6	166.1	-19.1	30.9	0	0	0	110.5	A292 V293 I294	P290-A292 PolarHBondContact O-N 3.35Å; P290-A292 VanDerWaalsContact O-N 3.08Å; P290-V293 HydrophobicContact CB-CG2 4.18Å; P290-V293 HydrophobicContact CG-CG2 4.09Å; P290-V293 PolarHBondContact O-N 3.26Å; P290-I294 WeakPolarHBondContact O-CG1 3.47Å; P290-I294 PolarHBondContact O-N 3.44Å
291	P	64.1	Low	74.6	Confident	57 Å²	57	25.9 Å²	25.9	37%	0.37	17%	0.172	S	C	.	.	H	α-helix	trans	-52.3	-35.3	178.7	-28.1	34.8	0	0	0	113.6	M48 V293 G295	M48-P291 HydrophobicContact CE-CG 3.77Å; P291-V293 VanDerWaalsContact C-N 3.26Å; P291-V293 PolarHBondContact O-N 3.49Å; P291-G295 PolarHBondContact O-N 3.43Å
292	A	63.1	Low	74.6	Confident	100 Å²	100	29.9 Å²	29.9	83%	0.826	19%	0.193	S	C	*	.	H	α-helix	trans	-64.5	-24.2	178.4	0	0	0	0	0	114.4	P290	P290-A292 PolarHBondContact O-N 3.35Å; P290-A292 VanDerWaalsContact O-N 3.08Å
293	V	66.1	Low	75	Confident	83 Å²	83	31.5 Å²	31.5	50%	0.503	20%	0.203	S	C	.	.	H	α-helix	trans	-89.2	-41.3	-176.8	177.2	0	0	0	0	111.6	F289 P290 P291	F289-V293 HydrophobicContact CD1-CG1 4.48Å; P290-V293 HydrophobicContact CB-CG2 4.18Å; P290-V293 HydrophobicContact CG-CG2 4.09Å; P290-V293 PolarHBondContact O-N 3.26Å; P291-V293 VanDerWaalsContact C-N 3.26Å; P291-V293 PolarHBondContact O-N 3.49Å
294	I	68.5	Low	75.9	Confident	10 Å²	10	31.5 Å²	31.5	5%	0.051	20%	0.203	C	C	.	.	H	α-helix	trans	-91.1	-20.8	-176.7	46.1	161.9	0	0	0	113.3	V109 V285 F289 P290 M297	V109-I294 HydrophobicContact CG2-CG2 3.96Å; V285-I294 HydrophobicContact CG1-CD1 3.83Å; F289-I294 HydrophobicContact CB-CB 4.2Å; F289-I294 HydrophobicContact CB-CD1 3.97Å; F289-I294 HydrophobicContact CB-CG1 3.83Å; F289-I294 HydrophobicContact CB-CG2 3.36Å; F289-I294 HydrophobicContact CD1-CG2 4.11Å; F289-I294 HydrophobicContact CD2-CG2 3.73Å; F289-I294 HydrophobicContact CG-CG2 3.45Å; F289-I294 VanDerWaalsContact CG-CG2 3.45Å; P290-I294 WeakPolarHBondContact O-CG1 3.47Å; P290-I294 PolarHBondContact O-N 3.44Å; I294-M297 HydrophobicContact CB-CB 4.42Å; I294-M297 VanDerWaalsContact O-CB 3.27Å; I294-M297 WeakPolarHBondContact O-CB 3.14Å; I294-M297 PolarHBondContact O-N 3.48Å
295	G	74.4	Confident	76.6	Confident	28 Å²	28	31.8 Å²	31.8	29%	0.289	21%	0.207	S	C	.	.	G	3₁₀ helix	trans	48.2	-130.4	179.6	0	0	0	0	0	111.2	P291 M297 Y298	P291-G295 PolarHBondContact O-N 3.43Å; G295-M297 PolarHBondContact O-N 2.9Å; G295-M297 VanDerWaalsContact O-N 3.1Å; G295-Y298 WeakPolarHBondContact O-CD1 3.24Å
296	P	75.8	Confident	77.2	Confident	26 Å²	26	38.8 Å²	38.8	17%	0.169	24%	0.237	C	C	.	.	G	3₁₀ helix	trans	-67	-11	-177.1	27.9	-34.7	0	0	0	114.9	T231 M232 Y298 L299	T231-P296 WeakPolarHBondContact OG1-CG 3.43Å; M232-P296 HydrophobicContact CE-CB 3.78Å; M232-P296 HydrophobicContact CE-CG 3.68Å; M232-P296 HydrophobicContact CG-CB 4.04Å; M232-P296 HydrophobicContact SD-CB 4.14Å; P296-Y298 PolarHBondContact O-N 2.88Å; P296-L299 WeakPolarHBondContact O-CB 3.47Å; P296-L299 PolarHBondContact O-N 2.98Å
297	M	80.6	Confident	78.1	Confident	10 Å²	10	39.3 Å²	39.3	5%	0.049	24%	0.24	C	C	.	.	G	3₁₀ helix	trans	-64.3	-14	-175.8	-71.9	-63	-59.7	0	0	114.5	T106 V109 M232 L237 I294 G295 L299 F300	T106-M297 HydrophobicContact CG2-CE 3.58Å; T106-M297 HydrophobicContact CG2-SD 3.91Å; V109-M297 HydrophobicContact CB-CE 3.94Å; V109-M297 HydrophobicContact CG1-CB 4.32Å; V109-M297 HydrophobicContact CG1-CE 3.76Å; V109-M297 HydrophobicContact CG2-CB 4.09Å; M232-M297 HydrophobicContact CE-CG 4.15Å; M232-M297 HydrophobicContact CE-SD 3.46Å; M232-M297 WeakPolarHBondContact CE-SD 3.37Å; M232-M297 HydrophobicContact SD-SD 4.07Å; L237-M297 HydrophobicContact CD1-SD 3.89Å; L237-M297 HydrophobicContact CD2-CE 4.31Å; L237-M297 HydrophobicContact CD2-SD 4.44Å; I294-M297 HydrophobicContact CB-CB 4.42Å; I294-M297 VanDerWaalsContact O-CB 3.27Å; I294-M297 WeakPolarHBondContact O-CB 3.14Å; I294-M297 PolarHBondContact O-N 3.48Å; G295-M297 PolarHBondContact O-N 2.9Å; G295-M297 VanDerWaalsContact O-N 3.1Å; M297-L299 PolarHBondContact O-N 3.48Å; M297-F300 HydrophobicContact CE-CB 3.81Å; M297-F300 HydrophobicContact CE-CD2 4.2Å; M297-F300 HydrophobicContact CE-CG 3.92Å; M297-F300 WeakPolarHBondContact O-CB 3.38Å; M297-F300 PolarHBondContact O-N 2.92Å; M297-F300 VanDerWaalsContact O-N 3.11Å
298	Y	78.7	Confident	79.4	Confident	6 Å²	6	37.8 Å²	37.8	2%	0.024	23%	0.23	C	C	.	.	G	3₁₀ helix	trans	-62.7	-18	170.4	75.9	-90.7	0	0	0	112.8	I217 C218 S221 G295 P296 P301	I217-Y298 HydrophobicContact CB-CE1 4.46Å; I217-Y298 HydrophobicContact CB-CE2 4.47Å; I217-Y298 HydrophobicContact CG2-CD1 3.71Å; I217-Y298 HydrophobicContact CG2-CE1 3.39Å; I217-Y298 HydrophobicContact CG2-CE2 4.18Å; I217-Y298 HydrophobicContact CG2-CG 4.32Å; C218-Y298 WeakPolarHBondContact CA-OH 3.26Å; C218-Y298 PolarHBondContact N-OH 3.47Å; C218-Y298 PolarHBondContact SG-OH 2.84Å; S221-Y298 PolarHBondContact OG-OH 3.22Å; G295-Y298 WeakPolarHBondContact O-CD1 3.24Å; P296-Y298 PolarHBondContact O-N 2.88Å; Y298-P301 WeakPolarHBondContact O-CD 3.48Å
299	L	80	Confident	80.6	Confident	23 Å²	23	40 Å²	40	12%	0.12	24%	0.241	C	C	.	.	G	3₁₀ helix	trans	-81.6	-21.4	175.9	-66.5	175.2	0	0	0	113.1	C218 L229 M232 P296 M297 P301 L302 V303	C218-L299 VanDerWaalsContact SG-CD2 3.57Å; L229-L299 HydrophobicContact CD2-CD1 3.85Å; M232-L299 HydrophobicContact CG-CB 4.32Å; M232-L299 HydrophobicContact CG-CD1 4.37Å; M232-L299 HydrophobicContact SD-CB 4.37Å; P296-L299 WeakPolarHBondContact O-CB 3.47Å; P296-L299 PolarHBondContact O-N 2.98Å; M297-L299 PolarHBondContact O-N 3.48Å; L299-P301 VanDerWaalsContact C-CD 3.44Å; L299-P301 VanDerWaalsContact C-N 3.35Å; L299-L302 HydrophobicContact CD2-CD1 4.2Å; L299-L302 WeakPolarHBondContact O-CB 3.5Å; L299-L302 PolarHBondContact O-N 2.95Å; L299-V303 PolarHBondContact O-N 3.38Å
300	F	86.9	Confident	81.7	Confident	2 Å²	2	41 Å²	41	1%	0.009	25%	0.254	C	S	.	.	H	α-helix	trans	-54.8	-41.5	-175.7	-176.9	-95.7	0	0	0	113.7	V109 I110 L237 I240 A241 M297 L302 V303 L304	V109-F300 HydrophobicContact CG1-CB 4.27Å; V109-F300 HydrophobicContact CG1-CD1 4.32Å; I110-F300 HydrophobicContact CD1-CZ 4.4Å; I110-F300 HydrophobicContact CG1-CD1 4.17Å; I110-F300 HydrophobicContact CG1-CE1 3.64Å; I110-F300 HydrophobicContact CG1-CE2 4.42Å; I110-F300 HydrophobicContact CG1-CZ 3.79Å; L237-F300 HydrophobicContact CB-CE2 4.31Å; L237-F300 HydrophobicContact CD2-CD2 4.42Å; L237-F300 HydrophobicContact CD2-CE2 4.27Å; I240-F300 HydrophobicContact CG2-CZ 4.06Å; A241-F300 HydrophobicContact CB-CE2 4.22Å; A241-F300 HydrophobicContact CB-CZ 4.37Å; M297-F300 HydrophobicContact CE-CB 3.81Å; M297-F300 HydrophobicContact CE-CD2 4.2Å; M297-F300 HydrophobicContact CE-CG 3.92Å; M297-F300 WeakPolarHBondContact O-CB 3.38Å; M297-F300 PolarHBondContact O-N 2.92Å; M297-F300 VanDerWaalsContact O-N 3.11Å; F300-L302 PolarHBondContact O-N 2.9Å; F300-V303 PolarHBondContact O-N 3.5Å; F300-V303 VanDerWaalsContact O-N 3.11Å; F300-L304 HydrophobicContact CE1-CB 4.41Å; F300-L304 WeakPolarHBondContact O-CB 3.3Å; F300-L304 PolarHBondContact O-N 3.38Å
301	P	89.3	Confident	83.2	Confident	0 Å²	0	38.4 Å²	38.4	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-57	-34.1	174.5	-25.3	35.2	0	0	0	113.6	I278 C281 A282 V285 Y298 L299 G305	I278-P301 HydrophobicContact CG2-CB 4.2Å; I278-P301 WeakPolarHBondContact CG2-O 3.27Å; C281-P301 HydrophobicContact CB-CB 4.13Å; C281-P301 HydrophobicContact CB-CG 4.3Å; A282-P301 HydrophobicContact CB-CB 4.08Å; A282-P301 HydrophobicContact CB-CG 4.32Å; V285-P301 HydrophobicContact CG2-CG 4.34Å; Y298-P301 WeakPolarHBondContact O-CD 3.48Å; L299-P301 VanDerWaalsContact C-CD 3.44Å; L299-P301 VanDerWaalsContact C-N 3.35Å; P301-G305 PolarHBondContact O-N 2.97Å
302	L	85.9	Confident	84.6	Confident	85 Å²	85	35.7 Å²	35.7	45%	0.445	22%	0.218	S	C	.	.	H	α-helix	trans	-71.1	-40.9	177	-61.3	176.9	0	0	0	111.6	L299 F300 G305 F306	L299-L302 HydrophobicContact CD2-CD1 4.2Å; L299-L302 WeakPolarHBondContact O-CB 3.5Å; L299-L302 PolarHBondContact O-N 2.95Å; F300-L302 PolarHBondContact O-N 2.9Å; L302-G305 PolarHBondContact O-N 3.13Å; L302-F306 PolarHBondContact O-N 3.47Å
303	V	89	Confident	86.1	Confident	38 Å²	38	33.2 Å²	33.2	23%	0.23	20%	0.197	C	C	.	.	H	α-helix	trans	-61.9	-46.8	174.8	179.6	0	0	0	0	110.1	A241 L299 F300 G305 F306 F307	A241-V303 HydrophobicContact CB-CG1 3.94Å; L299-V303 PolarHBondContact O-N 3.38Å; F300-V303 PolarHBondContact O-N 3.5Å; F300-V303 VanDerWaalsContact O-N 3.11Å; V303-G305 VanDerWaalsContact C-N 3.32Å; V303-G305 PolarHBondContact O-N 2.86Å; V303-F306 WeakPolarHBondContact O-CB 3.09Å; V303-F306 PolarHBondContact O-N 3.38Å; V303-F307 HydrophobicContact CG1-CD2 3.98Å; V303-F307 HydrophobicContact CG1-CE2 3.83Å; V303-F307 VanDerWaalsContact O-CD2 3.32Å; V303-F307 WeakPolarHBondContact O-CD2 3.38Å; V303-F307 PolarHBondContact O-N 3.39Å
304	L	91.9	Very high	87.5	Confident	1 Å²	1	34.2 Å²	34.2	1%	0.005	20%	0.199	C	C	.	.	H	α-helix	trans	-57.3	-45.7	173.8	-176.2	71.3	0	0	0	111.3	C113 L244 P245 I278 F300 F306 F307 Q308	C113-L304 HydrophobicContact CB-CD2 3.63Å; L244-L304 HydrophobicContact CB-CD1 4.19Å; L244-L304 HydrophobicContact CD2-CD1 3.98Å; L244-L304 HydrophobicContact CD2-CD2 4.15Å; P245-L304 HydrophobicContact CG-CD1 3.63Å; P245-L304 HydrophobicContact CG-CG 4.41Å; I278-L304 HydrophobicContact CD1-CB 4.49Å; I278-L304 HydrophobicContact CD1-CD2 4.14Å; I278-L304 HydrophobicContact CD1-CG 4.29Å; F300-L304 HydrophobicContact CE1-CB 4.41Å; F300-L304 WeakPolarHBondContact O-CB 3.3Å; F300-L304 PolarHBondContact O-N 3.38Å; L304-F306 VanDerWaalsContact C-N 3.32Å; L304-F306 PolarHBondContact O-N 3.48Å; L304-F307 PolarHBondContact O-N 3.17Å; L304-Q308 WeakPolarHBondContact O-CB 3.49Å; L304-Q308 PolarHBondContact O-N 3.06Å
305	G	90.5	Very high	88.7	Confident	11 Å²	11	36.6 Å²	36.6	11%	0.113	21%	0.212	C	C	.	.	H	α-helix	trans	-60.3	-39	177.5	0	0	0	0	0	113.5	P301 L302 V303 V309	P301-G305 PolarHBondContact O-N 2.97Å; L302-G305 PolarHBondContact O-N 3.13Å; V303-G305 VanDerWaalsContact C-N 3.32Å; V303-G305 PolarHBondContact O-N 2.86Å; G305-V309 VanDerWaalsContact O-CG2 3.25Å; G305-V309 WeakPolarHBondContact O-CG2 3.3Å; G305-V309 PolarHBondContact O-N 3.44Å; G305-V309 VanDerWaalsContact O-N 3.07Å
306	F	89.9	Confident	89.7	Confident	146 Å²	146	36.2 Å²	36.2	64%	0.64	20%	0.203	S	C	*	.	H	α-helix	trans	-61.4	-51.4	175.4	174.4	-94.3	0	0	0	111.6	L302 V303 L304 V309 A310	L302-F306 PolarHBondContact O-N 3.47Å; V303-F306 WeakPolarHBondContact O-CB 3.09Å; V303-F306 PolarHBondContact O-N 3.38Å; L304-F306 VanDerWaalsContact C-N 3.32Å; L304-F306 PolarHBondContact O-N 3.48Å; F306-V309 PolarHBondContact O-N 3.06Å; F306-A310 WeakPolarHBondContact O-CB 3.38Å; F306-A310 PolarHBondContact O-N 3.32Å
307	F	93.8	Very high	90.5	Very high	40 Å²	40	38.9 Å²	38.9	18%	0.175	22%	0.218	C	C	.	.	H	α-helix	trans	-65.8	-41.4	179.3	-76.7	-68.7	0	0	0	112.3	M238 A241 V242 V303 L304 V309 A310 E311	M238-F307 HydrophobicContact CE-CZ 3.99Å; A241-F307 HydrophobicContact CB-CD2 3.63Å; A241-F307 HydrophobicContact CB-CE2 4.11Å; A241-F307 HydrophobicContact CB-CG 4.49Å; A241-F307 WeakPolarHBondContact O-CB 3.39Å; V242-F307 HydrophobicContact CG2-CD1 3.4Å; V242-F307 VanDerWaalsContact CG2-CD1 3.4Å; V242-F307 HydrophobicContact CG2-CD2 4.28Å; V242-F307 HydrophobicContact CG2-CE1 3.49Å; V242-F307 VanDerWaalsContact CG2-CE1 3.49Å; V242-F307 HydrophobicContact CG2-CE2 4.35Å; V242-F307 HydrophobicContact CG2-CG 3.82Å; V242-F307 HydrophobicContact CG2-CZ 3.98Å; V303-F307 HydrophobicContact CG1-CD2 3.98Å; V303-F307 HydrophobicContact CG1-CE2 3.83Å; V303-F307 VanDerWaalsContact O-CD2 3.32Å; V303-F307 WeakPolarHBondContact O-CD2 3.38Å; V303-F307 PolarHBondContact O-N 3.39Å; L304-F307 PolarHBondContact O-N 3.17Å; F307-V309 VanDerWaalsContact C-N 3.31Å; F307-V309 PolarHBondContact O-N 2.97Å; F307-A310 PolarHBondContact O-N 3.45Å; F307-E311 WeakPolarHBondContact O-CB 3.42Å; F307-E311 WeakPolarHBondContact O-CG 3.33Å; F307-E311 PolarHBondContact O-N 3.35Å
308	Q	94.9	Very high	91.2	Very high	2 Å²	2	43.1 Å²	43.1	1%	0.009	24%	0.241	C	C	.	.	H	α-helix	trans	-54.1	-45.6	174.4	178.8	-179.4	-61	0	0	112.3	P245 Y249 G274 C275 Q276 L304 A312	P245-Q308 HydrophobicContact CB-CB 4.07Å; P245-Q308 HydrophobicContact CB-CG 4.32Å; P245-Q308 HydrophobicContact CG-CB 3.99Å; Y249-Q308 VanDerWaalsContact OH-CG 3.24Å; Y249-Q308 WeakPolarHBondContact OH-CG 3.2Å; Y249-Q308 PolarHBondContact OH-O 3.02Å; G274-Q308 PolarHBondContact O-OE1 2.87Å; C275-Q308 VanDerWaalsContact CA-CD 3.48Å; C275-Q308 PolarHBondContact SG-NE2 2.88Å; Q276-Q308 VanDerWaalsContact N-CD 3.32Å; Q276-Q308 PolarHBondContact O-NE2 3.48Å; Q276-Q308 VanDerWaalsContact O-NE2 3.16Å; L304-Q308 WeakPolarHBondContact O-CB 3.49Å; L304-Q308 PolarHBondContact O-N 3.06Å; Q308-A312 VanDerWaalsContact O-CB 3.31Å; Q308-A312 WeakPolarHBondContact O-CB 3.4Å; Q308-A312 PolarHBondContact O-N 2.7Å; Q308-A312 VanDerWaalsContact O-N 3.08Å
309	V	93.3	Very high	91.8	Very high	71 Å²	71	44.6 Å²	44.6	43%	0.43	25%	0.247	S	C	.	.	H	α-helix	trans	-68.8	-44.7	177.2	171.9	0	0	0	0	111.2	L121 G305 F306 F307 E311 A312 A313	L121-V309 HydrophobicContact CD2-CG2 3.63Å; G305-V309 VanDerWaalsContact O-CG2 3.25Å; G305-V309 WeakPolarHBondContact O-CG2 3.3Å; G305-V309 PolarHBondContact O-N 3.44Å; G305-V309 VanDerWaalsContact O-N 3.07Å; F306-V309 PolarHBondContact O-N 3.06Å; F307-V309 VanDerWaalsContact C-N 3.31Å; F307-V309 PolarHBondContact O-N 2.97Å; V309-E311 PolarHBondContact O-N 2.97Å; V309-A312 PolarHBondContact O-N 3.27Å; V309-A313 WeakPolarHBondContact O-CB 3.49Å; V309-A313 PolarHBondContact O-N 2.84Å
310	A	93.8	Very high	92.4	Very high	46 Å²	46	50.9 Å²	50.9	38%	0.38	27%	0.27	S	S	.	.	H	α-helix	trans	-60.9	-45.4	-179.3	0	0	0	0	0	111.7	F306 F307 A313 L314	F306-A310 WeakPolarHBondContact O-CB 3.38Å; F306-A310 PolarHBondContact O-N 3.32Å; F307-A310 PolarHBondContact O-N 3.45Å; A310-A313 PolarHBondContact O-N 3.17Å; A310-L314 PolarHBondContact O-N 2.89Å
311	E	96	Very high	92.6	Very high	21 Å²	21	53.7 Å²	53.7	10%	0.098	29%	0.289	C	S	.	.	H	α-helix	trans	-66.4	-42.7	176.8	-72.5	173.4	-163.3	0	0	112.1	V242 L246 Y249 F307 V309 A313 L314 L315	V242-E311 WeakPolarHBondContact CA-OE1 3.04Å; V242-E311 WeakPolarHBondContact CG1-OE1 3.12Å; L246-E311 VanDerWaalsContact CA-OE2 3.32Å; L246-E311 WeakPolarHBondContact CA-OE2 3.41Å; L246-E311 WeakPolarHBondContact CB-OE2 3.28Å; L246-E311 PolarHBondContact N-OE2 3.28Å; Y249-E311 HydrophobicContact CD2-CB 4.39Å; Y249-E311 HydrophobicContact CE2-CB 3.92Å; F307-E311 WeakPolarHBondContact O-CB 3.42Å; F307-E311 WeakPolarHBondContact O-CG 3.33Å; F307-E311 PolarHBondContact O-N 3.35Å; V309-E311 PolarHBondContact O-N 2.97Å; E311-A313 VanDerWaalsContact C-N 3.31Å; E311-A313 PolarHBondContact O-N 3.49Å; E311-L314 WeakPolarHBondContact O-CB 3.48Å; E311-L314 PolarHBondContact O-N 3.31Å; E311-L315 WeakPolarHBondContact O-CG 3.22Å; E311-L315 PolarHBondContact O-N 3.19Å
312	A	94.3	Very high	92.7	Very high	0 Å²	0	61.2 Å²	61.2	0%	0	32%	0.318	C	S	.	.	H	α-helix	trans	-60.8	-42.8	175	0	0	0	0	0	111.6	L125 M271 Q308 V309 L314 L315 I316	L125-A312 HydrophobicContact CD1-CB 3.55Å; L125-A312 HydrophobicContact CD2-CB 3.79Å; L125-A312 HydrophobicContact CG-CB 4.23Å; M271-A312 HydrophobicContact SD-CB 4.42Å; Q308-A312 VanDerWaalsContact O-CB 3.31Å; Q308-A312 WeakPolarHBondContact O-CB 3.4Å; Q308-A312 PolarHBondContact O-N 2.7Å; Q308-A312 VanDerWaalsContact O-N 3.08Å; V309-A312 PolarHBondContact O-N 3.27Å; A312-L314 VanDerWaalsContact C-N 3.34Å; A312-L314 PolarHBondContact O-N 2.8Å; A312-L315 PolarHBondContact O-N 3.06Å; A312-I316 WeakPolarHBondContact O-CB 3.2Å; A312-I316 WeakPolarHBondContact O-CD1 3.29Å; A312-I316 WeakPolarHBondContact O-CG1 3.31Å; A312-I316 PolarHBondContact O-N 3.41Å
313	A	94.3	Very high	92.7	Very high	49 Å²	49	59.9 Å²	59.9	41%	0.405	31%	0.309	S	S	.	.	H	α-helix	trans	-61	-43.7	175.5	0	0	0	0	0	111.3	V309 A310 E311 I316 V317	V309-A313 WeakPolarHBondContact O-CB 3.49Å; V309-A313 PolarHBondContact O-N 2.84Å; A310-A313 PolarHBondContact O-N 3.17Å; E311-A313 VanDerWaalsContact C-N 3.31Å; E311-A313 PolarHBondContact O-N 3.49Å; A313-I316 PolarHBondContact O-N 3.32Å; A313-V317 WeakPolarHBondContact O-CG2 3.34Å; A313-V317 PolarHBondContact O-N 2.77Å
314	L	95.6	Very high	92.6	Very high	104 Å²	104	64.3 Å²	64.3	55%	0.545	32%	0.322	S	S	.	.	H	α-helix	trans	-59.3	-48.4	174.9	-179.9	64.4	0	0	0	111.6	A310 E311 A312 I316 V317 L318	A310-L314 PolarHBondContact O-N 2.89Å; E311-L314 WeakPolarHBondContact O-CB 3.48Å; E311-L314 PolarHBondContact O-N 3.31Å; A312-L314 VanDerWaalsContact C-N 3.34Å; A312-L314 PolarHBondContact O-N 2.8Å; L314-I316 VanDerWaalsContact C-N 3.31Å; L314-I316 PolarHBondContact O-N 3.44Å; L314-V317 PolarHBondContact O-N 3.16Å; L314-L318 HydrophobicContact CD1-CD1 4.4Å; L314-L318 HydrophobicContact CD1-CG 4.37Å; L314-L318 HydrophobicContact CG-CD1 4.14Å; L314-L318 WeakPolarHBondContact O-CB 3.5Å; L314-L318 VanDerWaalsContact O-CG 3.32Å; L314-L318 WeakPolarHBondContact O-CG 3.47Å; L314-L318 PolarHBondContact O-N 3.31Å
315	L	94.7	Very high	92.4	Very high	59 Å²	59	70.8 Å²	70.8	31%	0.309	35%	0.35	S	S	.	.	H	α-helix	trans	-59.9	-40.2	177	-71	174.5	0	0	0	112.1	Y249 M271 E311 A312 F319	Y249-L315 HydrophobicContact CD1-CD1 4.34Å; Y249-L315 HydrophobicContact CD2-CD1 3.86Å; Y249-L315 HydrophobicContact CE2-CD1 4.5Å; Y249-L315 HydrophobicContact CG-CD1 3.79Å; M271-L315 HydrophobicContact CE-CB 3.95Å; M271-L315 HydrophobicContact CE-CD1 4.17Å; E311-L315 WeakPolarHBondContact O-CG 3.22Å; E311-L315 PolarHBondContact O-N 3.19Å; A312-L315 PolarHBondContact O-N 3.06Å; L315-F319 VanDerWaalsContact O-CB 3.3Å; L315-F319 WeakPolarHBondContact O-CB 3.35Å; L315-F319 PolarHBondContact O-N 3.46Å
316	I	93.9	Very high	92	Very high	21 Å²	21	73.3 Å²	73.3	11%	0.108	36%	0.364	C	S	.	.	H	α-helix	trans	-64.9	-44.5	176.1	-70	160.6	0	0	0	110.9	L125 A128 I129 M271 A312 A313 L314 F319 R320	L125-I316 HydrophobicContact CD2-CD1 3.73Å; A128-I316 HydrophobicContact CB-CD1 3.65Å; A128-I316 HydrophobicContact CB-CG1 4.14Å; A128-I316 HydrophobicContact CB-CG2 4.26Å; I129-I316 HydrophobicContact CB-CG1 4.31Å; M271-I316 HydrophobicContact CE-CG1 4.42Å; A312-I316 WeakPolarHBondContact O-CB 3.2Å; A312-I316 WeakPolarHBondContact O-CD1 3.29Å; A312-I316 WeakPolarHBondContact O-CG1 3.31Å; A312-I316 PolarHBondContact O-N 3.41Å; A313-I316 PolarHBondContact O-N 3.32Å; L314-I316 VanDerWaalsContact C-N 3.31Å; L314-I316 PolarHBondContact O-N 3.44Å; I316-F319 PolarHBondContact O-N 2.9Å; I316-R320 HydrophobicContact CG2-CG 4.45Å; I316-R320 WeakPolarHBondContact O-CB 3.21Å; I316-R320 WeakPolarHBondContact O-CG 3.48Å; I316-R320 PolarHBondContact O-N 2.88Å
317	V	94	Very high	91.2	Very high	81 Å²	81	69 Å²	69	49%	0.491	35%	0.35	S	S	.	.	H	α-helix	trans	-62.3	-49.2	177.8	169.8	0	0	0	0	110.4	A313 L314 F319 R320 C321	A313-V317 WeakPolarHBondContact O-CG2 3.34Å; A313-V317 PolarHBondContact O-N 2.77Å; L314-V317 PolarHBondContact O-N 3.16Å; V317-F319 VanDerWaalsContact C-N 3.3Å; V317-F319 PolarHBondContact O-N 3.36Å; V317-R320 PolarHBondContact O-N 3.46Å; V317-R320 VanDerWaalsContact O-N 3.13Å; V317-C321 WeakPolarHBondContact O-CB 3.38Å; V317-C321 PolarHBondContact O-N 2.99Å; V317-C321 PolarHBondContact O-SG 2.87Å; V317-C321 VanDerWaalsContact O-SG 3.33Å
318	L	93.7	Very high	89.7	Confident	100 Å²	100	72.6 Å²	72.6	52%	0.524	37%	0.365	S	S	.	.	H	α-helix	trans	-57.2	-44.8	177.1	-70.7	174.2	0	0	0	111.5	L314 C321 Y322	L314-L318 HydrophobicContact CD1-CD1 4.4Å; L314-L318 HydrophobicContact CD1-CG 4.37Å; L314-L318 HydrophobicContact CG-CD1 4.14Å; L314-L318 WeakPolarHBondContact O-CB 3.5Å; L314-L318 VanDerWaalsContact O-CG 3.32Å; L314-L318 WeakPolarHBondContact O-CG 3.47Å; L314-L318 PolarHBondContact O-N 3.31Å; L318-C321 PolarHBondContact O-N 3.24Å; L318-Y322 WeakPolarHBondContact O-CB 3.14Å; L318-Y322 PolarHBondContact O-N 2.94Å
319	F	92.7	Very high	87.7	Confident	36 Å²	36	74.9 Å²	74.9	16%	0.158	39%	0.389	C	S	.	.	H	α-helix	trans	-61.8	-44.9	175.8	170.8	-100.6	0	0	0	112.3	I129 K130 L315 I316 V317 Y322 H323	I129-F319 HydrophobicContact CB-CD1 4.4Å; I129-F319 HydrophobicContact CD1-CB 3.89Å; I129-F319 HydrophobicContact CD1-CG 4.12Å; I129-F319 HydrophobicContact CG1-CB 3.67Å; I129-F319 HydrophobicContact CG1-CD1 3.53Å; I129-F319 HydrophobicContact CG1-CD2 4.07Å; I129-F319 HydrophobicContact CG1-CE1 4.24Å; I129-F319 HydrophobicContact CG1-CG 3.44Å; I129-F319 VanDerWaalsContact CG1-CG 3.44Å; I129-F319 WeakPolarHBondContact O-CE1 3.33Å; K130-F319 HydrophobicContact CB-CE1 4.32Å; K130-F319 HydrophobicContact CB-CZ 4.36Å; K130-F319 HydrophobicContact CD-CE1 4.22Å; K130-F319 HydrophobicContact CD-CZ 4.28Å; K130-F319 HydrophobicContact CG-CE1 4.11Å; K130-F319 HydrophobicContact CG-CZ 4.45Å; L315-F319 VanDerWaalsContact O-CB 3.3Å; L315-F319 WeakPolarHBondContact O-CB 3.35Å; L315-F319 PolarHBondContact O-N 3.46Å; I316-F319 PolarHBondContact O-N 2.9Å; V317-F319 VanDerWaalsContact C-N 3.3Å; V317-F319 PolarHBondContact O-N 3.36Å; F319-Y322 PolarHBondContact O-N 3.01Å; F319-H323 HydrophobicContact CZ-CB 4.35Å; F319-H323 AromaticContact CZ-CD2 3.95Å; F319-H323 VanDerWaalsContact O-CB 3.28Å; F319-H323 WeakPolarHBondContact O-CB 3.1Å; F319-H323 PolarHBondContact O-N 3.49Å
320	R	91.4	Very high	85.7	Confident	156 Å²	156	79.3 Å²	79.3	59%	0.589	40%	0.403	S	S	*	.	H	α-helix	trans	-65.7	-42	179.4	-76.5	-175.5	176.5	-157.7	0.2	111.9	I316 V317 H323 W324	I316-R320 HydrophobicContact CG2-CG 4.45Å; I316-R320 WeakPolarHBondContact O-CB 3.21Å; I316-R320 WeakPolarHBondContact O-CG 3.48Å; I316-R320 PolarHBondContact O-N 2.88Å; V317-R320 PolarHBondContact O-N 3.46Å; V317-R320 VanDerWaalsContact O-N 3.13Å; R320-H323 PolarHBondContact O-N 3.49Å; R320-W324 VanDerWaalsContact O-CB 3.23Å; R320-W324 WeakPolarHBondContact O-CB 3.45Å; R320-W324 PolarHBondContact O-N 3.14Å
321	C	91.7	Very high	83.7	Confident	60 Å²	60	83.4 Å²	83.4	41%	0.405	42%	0.418	S	S	.	.	H	α-helix	trans	-59.5	-53.1	173.5	-70.4	0	0	0	0	110.5	V317 L318 H323 W324 F325	V317-C321 WeakPolarHBondContact O-CB 3.38Å; V317-C321 PolarHBondContact O-N 2.99Å; V317-C321 PolarHBondContact O-SG 2.87Å; V317-C321 VanDerWaalsContact O-SG 3.33Å; L318-C321 PolarHBondContact O-N 3.24Å; C321-H323 PolarHBondContact O-N 3.34Å; C321-W324 PolarHBondContact O-N 2.91Å; C321-F325 WeakPolarHBondContact O-CD2 3.25Å; C321-F325 PolarHBondContact O-N 3.44Å
322	Y	90.6	Very high	81.3	Confident	158 Å²	158	87.6 Å²	87.6	62%	0.62	45%	0.45	S	S	*	.	H	α-helix	trans	-55.7	-49	178.3	173.5	-98.1	0	0	0	112.1	L318 F319 W324 F325 T326	L318-Y322 WeakPolarHBondContact O-CB 3.14Å; L318-Y322 PolarHBondContact O-N 2.94Å; F319-Y322 PolarHBondContact O-N 3.01Å; Y322-W324 PolarHBondContact O-N 3.29Å; Y322-F325 PolarHBondContact O-N 3.21Å; Y322-T326 HydrophobicContact CE1-CG2 4.29Å; Y322-T326 HydrophobicContact CE2-CG2 3.98Å; Y322-T326 PolarHBondContact O-N 2.77Å; Y322-T326 PolarHBondContact O-OG1 3.3Å
323	H	86.9	Confident	79	Confident	57 Å²	57	96.4 Å²	96.4	26%	0.264	49%	0.485	S	S	.	.	H	α-helix	trans	-61.2	-45.8	178.7	-175.2	-61.5	0	0	0	111	K130 F319 R320 C321 F325 T326 T327	K130-H323 PolarHBondContact NZ-CE1 2.87Å; K130-H323 VanDerWaalsContact NZ-CE1 3.32Å; K130-H323 PolarHBondContact NZ-NE2 2.72Å; F319-H323 HydrophobicContact CZ-CB 4.35Å; F319-H323 AromaticContact CZ-CD2 3.95Å; F319-H323 VanDerWaalsContact O-CB 3.28Å; F319-H323 WeakPolarHBondContact O-CB 3.1Å; F319-H323 PolarHBondContact O-N 3.49Å; R320-H323 PolarHBondContact O-N 3.49Å; C321-H323 PolarHBondContact O-N 3.34Å; H323-F325 PolarHBondContact O-N 3.3Å; H323-T326 WeakPolarHBondContact CA-OG1 3.48Å; H323-T326 PolarHBondContact O-N 3.45Å; H323-T326 PolarHBondContact O-OG1 3.44Å; H323-T327 PolarHBondContact ND1-OG1 3.5Å; H323-T327 PolarHBondContact O-N 2.8Å; H323-T327 PolarHBondContact O-OG1 2.86Å
324	W	87.4	Confident	76.3	Confident	131 Å²	131	101.4 Å²	101.4	50%	0.496	50%	0.499	S	S	.	.	H	α-helix	trans	-58.7	-46.4	-179.9	-178	84.8	0	0	0	112.1	R320 C321 Y322 T327 K328	R320-W324 VanDerWaalsContact O-CB 3.23Å; R320-W324 WeakPolarHBondContact O-CB 3.45Å; R320-W324 PolarHBondContact O-N 3.14Å; C321-W324 PolarHBondContact O-N 2.91Å; Y322-W324 PolarHBondContact O-N 3.29Å; W324-T327 PolarHBondContact O-OG1 2.91Å; W324-K328 HydrophobicContact CD2-CD 4.32Å; W324-K328 HydrophobicContact CH2-CD 3.99Å; W324-K328 HydrophobicContact CZ2-CD 3.74Å; W324-K328 HydrophobicContact CZ3-CD 4.36Å; W324-K328 PolarHBondContact O-N 2.8Å; W324-K328 VanDerWaalsContact O-N 3.1Å
325	F	86.6	Confident	73.8	Confident	137 Å²	137	101 Å²	101	60%	0.601	50%	0.503	S	S	*	.	H	α-helix	trans	-65.3	-40.8	177.2	-77.2	-69.7	0	0	0	112.9	C321 Y322 H323 G329	C321-F325 WeakPolarHBondContact O-CD2 3.25Å; C321-F325 PolarHBondContact O-N 3.44Å; Y322-F325 PolarHBondContact O-N 3.21Å; H323-F325 PolarHBondContact O-N 3.3Å; F325-G329 PolarHBondContact O-N 3.25Å
326	T	81.8	Confident	71.2	Confident	64 Å²	64	103.2 Å²	103.2	39%	0.393	52%	0.519	S	S	.	.	H	α-helix	trans	-73.5	-32.1	-179.6	36.2	0	0	0	0	113.6	Y322 H323	Y322-T326 HydrophobicContact CE1-CG2 4.29Å; Y322-T326 HydrophobicContact CE2-CG2 3.98Å; Y322-T326 PolarHBondContact O-N 2.77Å; Y322-T326 PolarHBondContact O-OG1 3.3Å; H323-T326 WeakPolarHBondContact CA-OG1 3.48Å; H323-T326 PolarHBondContact O-N 3.45Å; H323-T326 PolarHBondContact O-OG1 3.44Å
327	T	73.3	Confident	69.1	Low	57 Å²	57	104.4 Å²	104.4	35%	0.35	53%	0.53	S	S	.	.	H	α-helix	trans	-73.9	-39.6	172.7	32.6	0	0	0	0	112.9	H323 W324 G329 K330 D331	H323-T327 PolarHBondContact ND1-OG1 3.5Å; H323-T327 PolarHBondContact O-N 2.8Å; H323-T327 PolarHBondContact O-OG1 2.86Å; W324-T327 PolarHBondContact O-OG1 2.91Å; T327-G329 VanDerWaalsContact C-N 3.26Å; T327-G329 PolarHBondContact O-N 3.42Å; T327-K330 PolarHBondContact O-N 3.5Å; T327-K330 VanDerWaalsContact O-N 3.08Å; T327-D331 PolarHBondContact O-N 2.92Å
328	K	62.1	Low	67	Low	114 Å²	114	105.1 Å²	105.1	50%	0.496	53%	0.534	S	S	.	.	H	α-helix	trans	-59.6	-35.9	175.7	-92.4	-169.6	168.1	-169.3	0	113	W324 K330 D331 S332	W324-K328 HydrophobicContact CD2-CD 4.32Å; W324-K328 HydrophobicContact CH2-CD 3.99Å; W324-K328 HydrophobicContact CZ2-CD 3.74Å; W324-K328 HydrophobicContact CZ3-CD 4.36Å; W324-K328 PolarHBondContact O-N 2.8Å; W324-K328 VanDerWaalsContact O-N 3.1Å; K328-K330 VanDerWaalsContact C-N 3.3Å; K328-K330 PolarHBondContact O-N 2.85Å; K328-D331 PolarHBondContact O-N 3.11Å; K328-S332 PolarHBondContact O-N 2.96Å; K328-S332 PolarHBondContact O-OG 3.22Å
329	G	53.8	Low	65	Low	50 Å²	50	108.5 Å²	108.5	52%	0.515	55%	0.547	S	S	.	.	H	α-helix	trans	-68.1	-24.7	176.7	0	0	0	0	0	114.5	F325 T327	F325-G329 PolarHBondContact O-N 3.25Å; T327-G329 VanDerWaalsContact C-N 3.26Å; T327-G329 PolarHBondContact O-N 3.42Å
330	K	50.7	Low	63.1	Low	164 Å²	164	113.7 Å²	113.7	71%	0.713	57%	0.572	S	S	*	*	H	α-helix	trans	-81.4	-32	176.7	-82.7	-176.8	173.6	-178.3	0	113	T327 K328 S332 Y333	T327-K330 PolarHBondContact O-N 3.5Å; T327-K330 VanDerWaalsContact O-N 3.08Å; K328-K330 VanDerWaalsContact C-N 3.3Å; K328-K330 PolarHBondContact O-N 2.85Å; K330-S332 VanDerWaalsContact C-N 3.31Å; K330-Y333 PolarHBondContact O-N 3.27Å
331	D	52.3	Low	61.2	Low	132 Å²	132	112.6 Å²	112.6	71%	0.706	57%	0.572	S	S	*	*	H	α-helix	trans	-76	-20.3	176.9	-64.2	-27.1	0	0	0	112.5	T327 K328	T327-D331 PolarHBondContact O-N 2.92Å; K328-D331 PolarHBondContact O-N 3.11Å
332	S	45.7	Very low	59.5	Low	109 Å²	109	115 Å²	115	76%	0.762	58%	0.58	S	S	*	*	T	Hydrogen-bonded Turn	trans	-85.5	-4.5	174.4	-65.1	0	0	0	0	114.9	K328 K330	K328-S332 PolarHBondContact O-N 2.96Å; K328-S332 PolarHBondContact O-OG 3.22Å; K330-S332 VanDerWaalsContact C-N 3.31Å
333	Y	44.8	Very low	57.8	Low	186 Å²	186	114.4 Å²	114.4	73%	0.729	58%	0.58	S	S	*	*			trans	-128	63.1	174.6	-155.3	-91.9	0	0	0	110.3	K330	K330-Y333 PolarHBondContact O-N 3.27Å
334	Q	38.9	Very low	56.3	Low	153 Å²	153	118.7 Å²	118.7	72%	0.715	60%	0.601	S	S	*	*			trans	-89.3	110	149.3	-79.5	-78.2	-37.6	0	0	105.8	T336	Q334-T336 PolarHBondContact O-N 2.7Å
335	P	42	Very low	55	Low	97 Å²	97	118 Å²	118	63%	0.63	61%	0.605	S	S	*	*			trans	-63.4	96	161.5	26.4	-28.5	0	0	0	105.7	S337	P335-S337 PolarHBondContact O-N 2.97Å
336	T	40.7	Very low	53.5	Low	105 Å²	105	115.8 Å²	115.8	64%	0.644	61%	0.607	S	S	*	*			trans	-46.1	103.1	169.9	-11.1	0	0	0	0	107.5	Q334 T338	Q334-T336 PolarHBondContact O-N 2.7Å; T336-T338 PolarHBondContact O-N 3.23Å; T336-T338 PolarHBondContact O-OG1 3.47Å
337	S	49.2	Very low	52.4	Low	46 Å²	46	119.9 Å²	119.9	32%	0.322	62%	0.622	S	S	.	*	S	Bend	trans	17.3	45.8	139.2	69	0	0	0	0	117	P335 K341	P335-S337 PolarHBondContact O-N 2.97Å; S337-K341 WeakPolarHBondContact O-CB 3.38Å; S337-K341 WeakPolarHBondContact O-CG 3.43Å; S337-K341 PolarHBondContact O-N 2.8Å
338	T	50.7	Low	51.5	Low	95 Å²	95	120.3 Å²	120.3	58%	0.583	64%	0.637	S	S	*	*	H	α-helix	trans	-81.3	-32.2	176.4	-56.7	0	0	0	0	108.1	T336 L342	T336-T338 PolarHBondContact O-N 3.23Å; T336-T338 PolarHBondContact O-OG1 3.47Å; T338-L342 HydrophobicContact CG2-CD1 3.94Å; T338-L342 VanDerWaalsContact O-CB 3.31Å; T338-L342 WeakPolarHBondContact O-CB 3.33Å; T338-L342 WeakPolarHBondContact O-CD1 3.14Å; T338-L342 VanDerWaalsContact O-CG 3.29Å; T338-L342 WeakPolarHBondContact O-CG 3.29Å; T338-L342 PolarHBondContact O-N 3.48Å
339	E	51.9	Low	51.2	Low	171 Å²	171	120.7 Å²	120.7	80%	0.799	65%	0.649	S	S	*	*	H	α-helix	trans	-72.3	-36.2	172.9	-76.2	-174.7	144.2	0	0	113.8	K343	E339-K343 PolarHBondContact O-N 3.47Å; E339-K343 VanDerWaalsContact O-N 3.16Å
340	E	52.7	Low	50.7	Low	145 Å²	145	126 Å²	126	68%	0.678	69%	0.689	S	S	*	*	H	α-helix	trans	-71.3	-40.4	174.4	-87.8	178.2	160.5	0	0	111.9	L342 K343 E344	E340-L342 PolarHBondContact O-N 3.14Å; E340-K343 PolarHBondContact O-N 2.89Å; E340-E344 PolarHBondContact O-N 3.3Å; E340-E344 VanDerWaalsContact O-N 3.15Å
341	K	51.8	Low	50.7	Low	134 Å²	134	124.2 Å²	124.2	58%	0.583	69%	0.687	S	S	*	*	H	α-helix	trans	-67.4	-33	174.9	-76.8	-172.7	174.7	-173.6	0	113.2	S337 I345	S337-K341 WeakPolarHBondContact O-CB 3.38Å; S337-K341 WeakPolarHBondContact O-CG 3.43Å; S337-K341 PolarHBondContact O-N 2.8Å; K341-I345 VanDerWaalsContact O-CD1 3.3Å; K341-I345 WeakPolarHBondContact O-CD1 3.17Å; K341-I345 WeakPolarHBondContact O-CG1 3.36Å; K341-I345 PolarHBondContact O-N 3.39Å
342	L	55.3	Low	50.6	Low	111 Å²	111	123.7 Å²	123.7	58%	0.581	69%	0.686	S	S	*	*	H	α-helix	trans	-72.8	-31.6	176.1	-82	161.2	0	0	0	112.6	T338 E340 S346	T338-L342 HydrophobicContact CG2-CD1 3.94Å; T338-L342 VanDerWaalsContact O-CB 3.31Å; T338-L342 WeakPolarHBondContact O-CB 3.33Å; T338-L342 WeakPolarHBondContact O-CD1 3.14Å; T338-L342 VanDerWaalsContact O-CG 3.29Å; T338-L342 WeakPolarHBondContact O-CG 3.29Å; T338-L342 PolarHBondContact O-N 3.48Å; E340-L342 PolarHBondContact O-N 3.14Å; L342-S346 WeakPolarHBondContact O-CB 3.31Å; L342-S346 PolarHBondContact O-N 3.28Å; L342-S346 VanDerWaalsContact O-N 3.08Å
343	K	55.1	Low	50.8	Low	144 Å²	144	124.6 Å²	124.6	63%	0.626	68%	0.682	S	S	*	*	H	α-helix	trans	-70.2	-42.5	173.7	-86.5	-176.4	173.4	-178.6	0	112.7	E339 E340 I345 S346 E347	E339-K343 PolarHBondContact O-N 3.47Å; E339-K343 VanDerWaalsContact O-N 3.16Å; E340-K343 PolarHBondContact O-N 2.89Å; K343-I345 VanDerWaalsContact C-N 3.31Å; K343-I345 PolarHBondContact O-N 3.33Å; K343-S346 PolarHBondContact O-N 3.12Å; K343-E347 WeakPolarHBondContact O-CB 3.27Å; K343-E347 PolarHBondContact O-N 2.87Å
344	E	54.9	Low	51.2	Low	148 Å²	148	120.9 Å²	120.9	69%	0.692	68%	0.679	S	S	*	*	H	α-helix	trans	-64.8	-33.5	176.2	-76.4	-175.3	157.8	0	0	112.8	E340 G348	E340-E344 PolarHBondContact O-N 3.3Å; E340-E344 VanDerWaalsContact O-N 3.15Å; E344-G348 PolarHBondContact O-N 2.78Å; E344-G348 VanDerWaalsContact O-N 3.11Å
345	I	60	Low	52	Low	116 Å²	116	118.9 Å²	118.9	60%	0.595	68%	0.677	S	S	*	*	H	α-helix	trans	-73.6	-34.6	175.7	-64.4	165.7	0	0	0	111.3	K341 K343 T349	K341-I345 VanDerWaalsContact O-CD1 3.3Å; K341-I345 WeakPolarHBondContact O-CD1 3.17Å; K341-I345 WeakPolarHBondContact O-CG1 3.36Å; K341-I345 PolarHBondContact O-N 3.39Å; K343-I345 VanDerWaalsContact C-N 3.31Å; K343-I345 PolarHBondContact O-N 3.33Å; I345-T349 PolarHBondContact O-OG1 3.35Å
346	S	55.3	Low	52.6	Low	90 Å²	90	120.4 Å²	120.4	63%	0.629	68%	0.68	S	S	*	*	H	α-helix	trans	-69.4	-34.9	175.4	174.3	0	0	0	0	113	L342 K343	L342-S346 WeakPolarHBondContact O-CB 3.31Å; L342-S346 PolarHBondContact O-N 3.28Å; L342-S346 VanDerWaalsContact O-N 3.08Å; K343-S346 PolarHBondContact O-N 3.12Å
347	E	59.8	Low	53.5	Low	151 Å²	151	121.5 Å²	121.5	71%	0.706	68%	0.683	S	S	*	*	H	α-helix	trans	-90.6	-16.1	-177.1	-70.2	179	174.1	0	0	113.1	K343	K343-E347 WeakPolarHBondContact O-CB 3.27Å; K343-E347 PolarHBondContact O-N 2.87Å
348	G	54.8	Low	53.8	Low	66 Å²	66	127.3 Å²	127.3	68%	0.68	71%	0.711	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.5	4	177	0	0	0	0	0	116	E344	E344-G348 PolarHBondContact O-N 2.78Å; E344-G348 VanDerWaalsContact O-N 3.11Å
349	T	54.9	Low	54.1	Low	122 Å²	122	130 Å²	130	75%	0.748	72%	0.721	S	S	*	*	T	Hydrogen-bonded Turn	trans	-125.6	28.1	-177	-25.7	0	0	0	0	113.8	I345	I345-T349 PolarHBondContact O-OG1 3.35Å
350	A	42.5	Very low	54.3	Low	162 Å²	162	126.3 Å²	126.3	100%	1.339	71%	0.714	S	S	*	*			trans	-112.7	0	176	0	0	0	0	0	112.3

Retrieved 350 of 350 residues in 206.3 ms (Link to these results)

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