A0A087YJW0_POEFO Loading...

Sodium-coupled neutral amino acid transporter 7

Symporter that selectively cotransports sodium ions and amino acids, such as L-glutamine and L-asparagine from the lysosome into the cytoplasm and may participates in mTORC1 activation. The transport activity requires an acidic lysosomal lumen.

AlphaFold DB , UniProt , Accession A0A087YJW0, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 457 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	31.6	Very low	30.4	Very low	246 Å²	246	148.9 Å²	148.9	100%	1.212	83%	0.828	S	S	*	*				0	92.9	0	-160.7	166.5	-173.5	0	0	105.1	I3	M1-I3 PolarHBondContact O-N 3.26Å
2	A	25.3	Very low	30.3	Very low	99 Å²	99	142.1 Å²	142.1	82%	0.818	82%	0.816	S	S	*	*			trans	-77.8	119.8	-171.7	0	0	0	0	0	108.3	N4	A2-N4 PolarHBondContact O-N 3.44Å
3	I	30.7	Very low	30.4	Very low	132 Å²	132	143.2 Å²	143.2	68%	0.677	82%	0.815	S	S	*	*			trans	-68.9	125.9	167.7	-62.2	173.5	0	0	0	105.7	M1 T5	M1-I3 PolarHBondContact O-N 3.26Å; I3-T5 PolarHBondContact O-N 2.92Å; I3-T5 VanDerWaalsContact O-N 3.1Å
4	N	29.2	Very low	30.4	Very low	142 Å²	142	139.1 Å²	139.1	76%	0.759	82%	0.82	S	S	*	*			trans	-43.5	113.4	-177.6	-102.1	-7	0	0	0	112.2	A2 D6	A2-N4 PolarHBondContact O-N 3.44Å; N4-D6 VanDerWaalsContact C-N 3.27Å; N4-D6 PolarHBondContact O-N 2.87Å
5	T	32.8	Very low	30.7	Very low	130 Å²	130	131.7 Å²	131.7	80%	0.798	79%	0.786	S	S	*	*			trans	-90.3	55.6	169.3	47.1	0	0	0	0	109.9	I3	I3-T5 PolarHBondContact O-N 2.92Å; I3-T5 VanDerWaalsContact O-N 3.1Å
6	D	30.4	Very low	31.5	Very low	134 Å²	134	125.9 Å²	125.9	72%	0.717	75%	0.753	S	S	*	*			trans	-123.8	67.1	173.2	-66.6	-35.9	0	0	0	108.6	N4	N4-D6 VanDerWaalsContact C-N 3.27Å; N4-D6 PolarHBondContact O-N 2.87Å
7	A	30.6	Very low	32.2	Very low	101 Å²	101	124.1 Å²	124.1	84%	0.835	75%	0.748	S	S	*	*			trans	-92.1	94.6	157.3	0	0	0	0	0	106.3
8	E	30.6	Very low	33.3	Very low	188 Å²	188	120.5 Å²	120.5	88%	0.879	72%	0.724	S	S	*	*			trans	-55.6	139.4	174.7	-80.7	-174	129.7	0	0	111.4	W10	E8-W10 PolarHBondContact O-N 3.34Å
9	D	33	Very low	34.2	Very low	144 Å²	144	114.6 Å²	114.6	77%	0.77	69%	0.689	S	S	*	*			trans	-60.2	115.6	-168.4	-166	6.2	0	0	0	112.9	G11	D9-G11 PolarHBondContact OD1-N 3.07Å
10	W	33.1	Very low	35.1	Very low	257 Å²	257	109 Å²	109	97%	0.973	66%	0.656	S	S	*	*			trans	-125.7	84.9	152.3	-88	81.4	0	0	0	108.6	E8	E8-W10 PolarHBondContact O-N 3.34Å
11	G	26.6	Very low	35.9	Very low	65 Å²	65	109 Å²	109	67%	0.67	65%	0.649	S	S	*	*	S	Bend	trans	57.8	83.1	133	0	0	0	0	0	117.3	D9	D9-G11 PolarHBondContact OD1-N 3.07Å
12	G	30.2	Very low	37.1	Very low	67 Å²	67	99.4 Å²	99.4	69%	0.691	60%	0.599	S	S	*	*			trans	78.8	91.5	146	0	0	0	0	0	117.1
13	I	31.1	Very low	38.5	Very low	156 Å²	156	95 Å²	95	80%	0.8	56%	0.562	S	S	*	*			trans	175.3	103.5	135	-83.1	148.2	0	0	0	106.4	G15	I13-G15 PolarHBondContact O-N 3.12Å
14	G	31	Very low	39.7	Very low	86 Å²	86	93.3 Å²	93.3	89%	0.887	55%	0.547	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.8	34.3	172.7	0	0	0	0	0	114.5
15	G	35	Very low	40.9	Very low	29 Å²	29	90.1 Å²	90.1	30%	0.299	53%	0.53	S	S	.	.	T	Hydrogen-bonded Turn	trans	-104.4	-9	-167.2	0	0	0	0	0	116.8	I13 S19	I13-G15 PolarHBondContact O-N 3.12Å; G15-S19 PolarHBondContact O-OG 3.2Å
16	S	42.5	Very low	41.7	Very low	38 Å²	38	85.3 Å²	85.3	27%	0.266	50%	0.499	S	S	.	.	T	Hydrogen-bonded Turn	trans	-93.8	-22.6	-161.9	72.2	0	0	0	0	116.9	R115 K120	S16-R115 PolarHBondContact O-NH2 2.78Å; S16-K120 VanDerWaalsContact OG-CE 3.27Å; S16-K120 WeakPolarHBondContact OG-CE 3.25Å; S16-K120 PolarHBondContact OG-NZ 2.96Å
17	S	44	Very low	42.8	Very low	95 Å²	95	79.8 Å²	79.8	66%	0.664	47%	0.469	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.1	-44.9	175.4	-162.7	0	0	0	0	110.2	S19 G20 E21	S17-S19 VanDerWaalsContact C-N 3.3Å; S17-S19 PolarHBondContact O-N 3.45Å; S17-G20 PolarHBondContact O-N 3.38Å; S17-E21 PolarHBondContact O-N 3.48Å
18	D	52.4	Low	43.6	Very low	60 Å²	60	75.7 Å²	75.7	32%	0.321	44%	0.435	S	S	.	.	H	α-helix	trans	-62.9	-32.5	-176.1	-164.3	-1.9	0	0	0	112.6	G20 E21 R22	D18-G20 PolarHBondContact O-N 3.01Å; D18-E21 PolarHBondContact O-N 3.23Å; D18-R22 VanDerWaalsContact O-CB 3.28Å; D18-R22 WeakPolarHBondContact O-CB 3.49Å; D18-R22 VanDerWaalsContact O-CD 3.25Å; D18-R22 WeakPolarHBondContact O-CD 3.49Å; D18-R22 WeakPolarHBondContact O-CG 3.48Å; D18-R22 PolarHBondContact O-N 2.99Å; D18-R22 WeakPolarHBondContact OD1-CG 3.21Å; D18-R22 IonicContact OD1-CZ 3.69Å; D18-R22 IonicContact OD1-NE 2.8Å; D18-R22 PolarHBondContact OD1-NE 2.96Å; D18-R22 IonicContact OD1-NH2 3.81Å; D18-R22 IonicContact OD2-CZ 3.22Å; D18-R22 IonicContact OD2-NE 3.16Å; D18-R22 PolarHBondContact OD2-NE 3.07Å; D18-R22 VanDerWaalsContact OD2-NE 3.16Å; D18-R22 IonicContact OD2-NH2 2.63Å; D18-R22 PolarHBondContact OD2-NH2 3.1Å
19	S	49.3	Very low	44.1	Very low	8 Å²	8	70.8 Å²	70.8	6%	0.056	42%	0.419	C	S	.	.	H	α-helix	trans	-67.9	-36	-179	-60	0	0	0	0	114.6	G15 S17 A23 R349	G15-S19 PolarHBondContact O-OG 3.2Å; S17-S19 VanDerWaalsContact C-N 3.3Å; S17-S19 PolarHBondContact O-N 3.45Å; S19-A23 PolarHBondContact O-N 3.47Å; S19-R349 VanDerWaalsContact CB-CG 3.47Å
20	G	51.7	Low	44.3	Very low	2 Å²	2	67.7 Å²	67.7	2%	0.021	41%	0.408	C	S	.	.	H	α-helix	trans	-72.9	-43.3	175.5	0	0	0	0	0	111.4	S17 D18 R22 A23 W24 E112	S17-G20 PolarHBondContact O-N 3.38Å; D18-G20 PolarHBondContact O-N 3.01Å; G20-R22 VanDerWaalsContact C-N 3.33Å; G20-R22 PolarHBondContact O-N 3.05Å; G20-A23 PolarHBondContact O-N 3.31Å; G20-W24 WeakPolarHBondContact O-CB 3.27Å; G20-W24 PolarHBondContact O-N 3.33Å; G20-E112 VanDerWaalsContact CA-OE1 3.28Å; G20-E112 WeakPolarHBondContact CA-OE1 3.45Å
21	E	53.7	Low	44.3	Very low	109 Å²	109	59.8 Å²	59.8	51%	0.509	39%	0.388	S	S	.	.	H	α-helix	trans	-61.4	-39.7	175.3	-157.3	174.2	170.3	0	0	111.9	S17 D18 W24 L25	S17-E21 PolarHBondContact O-N 3.48Å; D18-E21 PolarHBondContact O-N 3.23Å; E21-W24 PolarHBondContact O-N 3.38Å; E21-L25 WeakPolarHBondContact O-CB 3.29Å; E21-L25 VanDerWaalsContact O-CG 3.24Å; E21-L25 WeakPolarHBondContact O-CG 3.29Å; E21-L25 PolarHBondContact O-N 3.22Å
22	R	56.5	Low	44.3	Very low	46 Å²	46	64.4 Å²	64.4	17%	0.174	40%	0.398	C	S	.	.	H	α-helix	trans	-63.7	-46.8	172.6	-71.9	162.6	-168.9	-158.4	-3.7	112.6	D18 G20 W24 L25 L26 E353 V355	D18-R22 VanDerWaalsContact O-CB 3.28Å; D18-R22 WeakPolarHBondContact O-CB 3.49Å; D18-R22 VanDerWaalsContact O-CD 3.25Å; D18-R22 WeakPolarHBondContact O-CD 3.49Å; D18-R22 WeakPolarHBondContact O-CG 3.48Å; D18-R22 PolarHBondContact O-N 2.99Å; D18-R22 WeakPolarHBondContact OD1-CG 3.21Å; D18-R22 IonicContact OD1-CZ 3.69Å; D18-R22 IonicContact OD1-NE 2.8Å; D18-R22 PolarHBondContact OD1-NE 2.96Å; D18-R22 IonicContact OD1-NH2 3.81Å; D18-R22 IonicContact OD2-CZ 3.22Å; D18-R22 IonicContact OD2-NE 3.16Å; D18-R22 PolarHBondContact OD2-NE 3.07Å; D18-R22 VanDerWaalsContact OD2-NE 3.16Å; D18-R22 IonicContact OD2-NH2 2.63Å; D18-R22 PolarHBondContact OD2-NH2 3.1Å; G20-R22 VanDerWaalsContact C-N 3.33Å; G20-R22 PolarHBondContact O-N 3.05Å; R22-W24 VanDerWaalsContact C-N 3.31Å; R22-W24 PolarHBondContact O-N 3.35Å; R22-L25 PolarHBondContact O-N 3.42Å; R22-L26 VanDerWaalsContact O-CG 3.24Å; R22-L26 WeakPolarHBondContact O-CG 3.29Å; R22-L26 PolarHBondContact O-N 3.08Å; R22-E353 PolarHBondContact NH1-O 3.22Å; R22-V355 HydrophobicContact CG-CG2 4.23Å; R22-V355 VanDerWaalsContact NH2-CG2 3.3Å
23	A	53.2	Low	44.3	Very low	5 Å²	5	66.6 Å²	66.6	4%	0.041	40%	0.402	C	S	.	.	H	α-helix	trans	-62.4	-42.5	178.2	0	0	0	0	0	110.9	S19 G20 L26 Q27 L348	S19-A23 PolarHBondContact O-N 3.47Å; G20-A23 PolarHBondContact O-N 3.31Å; A23-L26 PolarHBondContact O-N 2.87Å; A23-Q27 WeakPolarHBondContact O-CB 3.45Å; A23-Q27 VanDerWaalsContact O-CG 3.27Å; A23-Q27 WeakPolarHBondContact O-CG 3.02Å; A23-Q27 PolarHBondContact O-N 3.38Å; A23-Q27 PolarHBondContact O-OE1 3.12Å; A23-L348 HydrophobicContact CB-CD1 4.13Å
24	W	56.8	Low	44.3	Very low	97 Å²	97	63.9 Å²	63.9	37%	0.367	40%	0.403	S	S	.	.	H	α-helix	trans	-59.8	-51.1	172.6	174.9	77.3	0	0	0	111.6	G20 E21 R22 L26 Q27 S28	G20-W24 WeakPolarHBondContact O-CB 3.27Å; G20-W24 PolarHBondContact O-N 3.33Å; E21-W24 PolarHBondContact O-N 3.38Å; R22-W24 VanDerWaalsContact C-N 3.31Å; R22-W24 PolarHBondContact O-N 3.35Å; W24-L26 PolarHBondContact O-N 3.33Å; W24-Q27 CarbonylContact O-C 3.59Å; W24-Q27 PolarHBondContact O-N 3.1Å; W24-Q27 VanDerWaalsContact O-N 3.09Å; W24-S28 WeakPolarHBondContact O-CA 3.48Å; W24-S28 VanDerWaalsContact O-CB 3.27Å; W24-S28 WeakPolarHBondContact O-CB 3.2Å; W24-S28 PolarHBondContact O-N 2.84Å
25	L	55	Low	44.2	Very low	76 Å²	76	70.7 Å²	70.7	40%	0.398	40%	0.402	S	S	.	.	H	α-helix	trans	-54.2	-53.4	178	-77.7	168.8	0	0	0	110.1	E21 R22 Q27 S28 V31	E21-L25 WeakPolarHBondContact O-CB 3.29Å; E21-L25 VanDerWaalsContact O-CG 3.24Å; E21-L25 WeakPolarHBondContact O-CG 3.29Å; E21-L25 PolarHBondContact O-N 3.22Å; R22-L25 PolarHBondContact O-N 3.42Å; L25-Q27 PolarHBondContact O-N 2.94Å; L25-S28 PolarHBondContact O-N 3.22Å; L25-S28 VanDerWaalsContact O-N 3.15Å; L25-S28 PolarHBondContact O-OG 3.43Å; L25-V31 WeakPolarHBondContact O-CG2 3.42Å
26	L	50	Low	43.7	Very low	28 Å²	28	78.2 Å²	78.2	15%	0.147	43%	0.429	C	S	.	.	H	α-helix	trans	-60.1	-22.8	-178.4	-66	-179.6	0	0	0	114.2	R22 A23 W24 L348 V359 E362 R366	R22-L26 VanDerWaalsContact O-CG 3.24Å; R22-L26 WeakPolarHBondContact O-CG 3.29Å; R22-L26 PolarHBondContact O-N 3.08Å; A23-L26 PolarHBondContact O-N 2.87Å; W24-L26 PolarHBondContact O-N 3.33Å; L26-L348 HydrophobicContact CD1-CD1 4.27Å; L26-V359 HydrophobicContact CD2-CG2 4.06Å; L26-E362 HydrophobicContact CB-CG 4.24Å; L26-E362 HydrophobicContact CD1-CG 4.15Å; L26-E362 HydrophobicContact CD2-CB 4.42Å; L26-E362 HydrophobicContact CD2-CG 3.65Å; L26-E362 HydrophobicContact CG-CG 4.21Å; L26-R366 PolarHBondContact O-NH2 3.45Å
27	Q	52.3	Low	43.2	Very low	18 Å²	18	81.6 Å²	81.6	8%	0.084	45%	0.45	C	S	.	.	H	α-helix	trans	-108.2	-12.2	-177.4	-65.5	161.1	13	0	0	113.2	A23 W24 L25 F337 A341 E344	A23-Q27 WeakPolarHBondContact O-CB 3.45Å; A23-Q27 VanDerWaalsContact O-CG 3.27Å; A23-Q27 WeakPolarHBondContact O-CG 3.02Å; A23-Q27 PolarHBondContact O-N 3.38Å; A23-Q27 PolarHBondContact O-OE1 3.12Å; W24-Q27 CarbonylContact O-C 3.59Å; W24-Q27 PolarHBondContact O-N 3.1Å; W24-Q27 VanDerWaalsContact O-N 3.09Å; L25-Q27 PolarHBondContact O-N 2.94Å; Q27-F337 HydrophobicContact CB-CZ 4.29Å; Q27-F337 WeakPolarHBondContact O-CZ 3.25Å; Q27-A341 PolarHBondContact NE2-O 2.88Å; Q27-A341 PolarHBondContact OE1-O 2.92Å; Q27-E344 VanDerWaalsContact NE2-CG 3.29Å
28	S	47.7	Very low	42.7	Very low	16 Å²	16	86.6 Å²	86.6	11%	0.112	46%	0.463	C	S	.	.			trans	-64.7	135.2	179.4	69.1	0	0	0	0	109.3	W24 L25 S30 V31	W24-S28 WeakPolarHBondContact O-CA 3.48Å; W24-S28 VanDerWaalsContact O-CB 3.27Å; W24-S28 WeakPolarHBondContact O-CB 3.2Å; W24-S28 PolarHBondContact O-N 2.84Å; L25-S28 PolarHBondContact O-N 3.22Å; L25-S28 VanDerWaalsContact O-N 3.15Å; L25-S28 PolarHBondContact O-OG 3.43Å; S28-S30 PolarHBondContact O-N 3.46Å; S28-V31 WeakPolarHBondContact OG-CG2 3.28Å
29	P	41	Very low	41.7	Very low	84 Å²	84	88.1 Å²	88.1	55%	0.545	48%	0.484	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.6	2.7	177.3	-21.4	32.3	0	0	0	114.8
30	S	37.7	Very low	41	Very low	79 Å²	79	97.2 Å²	97.2	55%	0.552	53%	0.526	S	S	*	.	T	Hydrogen-bonded Turn	trans	-127.7	17.8	-163.6	53.2	0	0	0	0	114.9	S28 D32	S28-S30 PolarHBondContact O-N 3.46Å; S30-D32 PolarHBondContact O-N 3.46Å
31	V	32.5	Very low	40.2	Very low	91 Å²	91	106.7 Å²	106.7	55%	0.552	57%	0.569	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.6	63.7	174.3	-165.5	0	0	0	0	111.6	L25 S28	L25-V31 WeakPolarHBondContact O-CG2 3.42Å; S28-V31 WeakPolarHBondContact OG-CG2 3.28Å
32	D	26.2	Very low	39.5	Very low	163 Å²	163	105.1 Å²	105.1	87%	0.872	58%	0.582	S	S	*	*	T	Hydrogen-bonded Turn	trans	-142.9	25.1	160.1	-96.6	-23.4	0	0	0	111.7	S30	S30-D32 PolarHBondContact O-N 3.46Å
33	S	30.5	Very low	39.1	Very low	112 Å²	112	107.5 Å²	107.5	78%	0.783	61%	0.606	S	S	*	*			trans	-135.3	72.6	171.8	-72.3	0	0	0	0	111.8	R35	S33-R35 PolarHBondContact O-N 2.63Å
34	A	30.4	Very low	39.6	Very low	99 Å²	99	119.3 Å²	119.3	82%	0.818	65%	0.65	S	S	*	*			trans	-68.4	111.3	150.9	0	0	0	0	0	108.5
35	R	29.1	Very low	40.3	Very low	230 Å²	230	116.1 Å²	116.1	87%	0.868	65%	0.647	S	S	*	*			trans	60.7	97.6	161.4	-57.4	-179.1	-172.5	176.1	2.4	117.1	S33	S33-R35 PolarHBondContact O-N 2.63Å
36	H	24.8	Very low	41.6	Very low	186 Å²	186	114.4 Å²	114.4	86%	0.861	64%	0.64	S	S	*	*			trans	-145.4	139.1	139.4	-112.5	-85.1	0	0	0	109.8
37	P	31.4	Very low	43.5	Very low	110 Å²	110	116 Å²	116	71%	0.714	65%	0.653	S	S	*	*			trans	-75.6	137.5	-175.2	2	15.2	0	0	0	110.9	A39	P37-A39 PolarHBondContact O-N 3.16Å
38	E	34.6	Very low	45.3	Very low	200 Å²	200	117 Å²	117	94%	0.935	66%	0.664	S	S	*	*	S	Bend	trans	25.1	79.5	152.1	-61.3	-176.8	151.2	0	0	117.8
39	A	32.4	Very low	47.2	Very low	92 Å²	92	121.9 Å²	121.9	76%	0.76	69%	0.688	S	S	*	*			trans	-171.1	133.8	147.2	0	0	0	0	0	109.8	P37	P37-A39 PolarHBondContact O-N 3.16Å
40	E	32.8	Very low	49.4	Very low	198 Å²	198	118.7 Å²	118.7	93%	0.925	67%	0.671	S	S	*	*			trans	94.5	57.1	177.5	-54.3	-153.1	157.7	0	0	119.3
41	E	36.7	Very low	51.8	Low	201 Å²	201	115 Å²	115	94%	0.939	65%	0.645	S	S	*	*			trans	-96.1	18.6	165.3	-89.1	-165.1	147.9	0	0	114.8	S43	E41-S43 PolarHBondContact O-N 2.8Å
42	G	37.6	Very low	54.6	Low	76 Å²	76	111 Å²	111	78%	0.784	62%	0.621	S	S	*	*	S	Bend	trans	-78.4	-13	-168.6	0	0	0	0	0	118.4
43	S	47.5	Very low	57.5	Low	97 Å²	97	107.7 Å²	107.7	68%	0.678	60%	0.599	S	S	*	*	S	Bend	trans	-136.5	-22	-158.9	-178	0	0	0	0	117.8	E41	E41-S43 PolarHBondContact O-N 2.8Å
44	R	63.7	Low	60.2	Low	253 Å²	253	103.1 Å²	103.1	96%	0.955	57%	0.565	S	S	*	*			trans	-90.2	-7.1	-163.7	-81.3	179.1	135.7	154.7	-5.8	117.9
45	G	72.8	Confident	63	Low	29 Å²	29	98.6 Å²	98.6	30%	0.299	53%	0.528	S	S	.	.	S	Bend	trans	-80.8	157.8	-179.9	0	0	0	0	0	114.7	S263 K265	G45-S263 CarbonylContact C-O 3.56Å; G45-S263 WeakPolarHBondContact CA-O 3.46Å; G45-K265 WeakPolarHBondContact O-CE 3.44Å; G45-K265 WeakPolarHBondContact O-CG 3.29Å
46	V	82.9	Confident	66	Low	41 Å²	41	87.7 Å²	87.7	25%	0.248	49%	0.487	C	S	.	.	B	Isolated β-bridge	trans	-70.2	134.9	171.9	-177.1	0	0	0	0	109.8	A51 I54 S263 M264 K265	V46-A51 HydrophobicContact CG1-CB 4.3Å; V46-I54 HydrophobicContact CG1-CD1 3.97Å; V46-I54 HydrophobicContact CG2-CD1 4.4Å; V46-S263 PolarHBondContact N-O 3.16Å; V46-M264 WeakPolarHBondContact O-CA 3.18Å; V46-K265 PolarHBondContact O-N 3.35Å
47	S	89.8	Confident	68.9	Low	61 Å²	61	79 Å²	79	43%	0.427	45%	0.446	S	S	.	.	P	Polyproline II helix	trans	-69.1	158.8	175	66.6	0	0	0	0	111.2	L49 G50 A51	S47-L49 VanDerWaalsContact C-N 3.27Å; S47-L49 PolarHBondContact O-N 2.91Å; S47-G50 WeakPolarHBondContact O-CA 3.43Å; S47-G50 PolarHBondContact O-N 2.82Å; S47-G50 PolarHBondContact OG-N 3.27Å; S47-G50 VanDerWaalsContact OG-N 3.11Å; S47-A51 PolarHBondContact O-N 3.43Å
48	A	89.6	Confident	71.5	Confident	39 Å²	39	75.3 Å²	75.3	32%	0.322	43%	0.425	S	S	.	.	H	α-helix	trans	-56.5	-41.7	177.6	0	0	0	0	0	112.2	A51 V52 V275	A48-A51 WeakPolarHBondContact O-CB 3.44Å; A48-A51 PolarHBondContact O-N 2.96Å; A48-V52 WeakPolarHBondContact O-CG2 3.45Å; A48-V52 PolarHBondContact O-N 3.01Å; A48-V275 HydrophobicContact CB-CG2 3.94Å; A48-V275 WeakPolarHBondContact O-CG2 3.49Å
49	L	88.1	Confident	74.1	Confident	118 Å²	118	66 Å²	66	62%	0.618	38%	0.383	S	S	*	.	H	α-helix	trans	-63.8	-41.7	174.3	-69	174.3	0	0	0	112.3	S47 A51 V52 F53	S47-L49 VanDerWaalsContact C-N 3.27Å; S47-L49 PolarHBondContact O-N 2.91Å; L49-A51 VanDerWaalsContact C-N 3.29Å; L49-A51 PolarHBondContact O-N 3.39Å; L49-V52 WeakPolarHBondContact O-CB 3.2Å; L49-V52 PolarHBondContact O-N 3.36Å; L49-F53 WeakPolarHBondContact O-CD2 3.42Å; L49-F53 PolarHBondContact O-N 3.23Å
50	G	86.4	Confident	76.7	Confident	18 Å²	18	61.6 Å²	61.6	19%	0.186	35%	0.347	C	S	.	.	H	α-helix	trans	-61.5	-39.1	174.3	0	0	0	0	0	112.2	S47 V52 F53 I54	S47-G50 WeakPolarHBondContact O-CA 3.43Å; S47-G50 PolarHBondContact O-N 2.82Å; S47-G50 PolarHBondContact OG-N 3.27Å; S47-G50 VanDerWaalsContact OG-N 3.11Å; G50-V52 VanDerWaalsContact C-N 3.34Å; G50-F53 PolarHBondContact O-N 3.39Å; G50-I54 WeakPolarHBondContact O-CG1 3.39Å; G50-I54 PolarHBondContact O-N 3.45Å; G50-I54 VanDerWaalsContact O-N 3.09Å
51	A	88.7	Confident	78.7	Confident	0 Å²	0	52.5 Å²	52.5	0%	0	31%	0.306	C	S	.	.	H	α-helix	trans	-65.6	-36.7	175.6	0	0	0	0	0	111.7	V46 S47 A48 L49 I54 V55 V260 M264 V275	V46-A51 HydrophobicContact CG1-CB 4.3Å; S47-A51 PolarHBondContact O-N 3.43Å; A48-A51 WeakPolarHBondContact O-CB 3.44Å; A48-A51 PolarHBondContact O-N 2.96Å; L49-A51 VanDerWaalsContact C-N 3.29Å; L49-A51 PolarHBondContact O-N 3.39Å; A51-I54 PolarHBondContact O-N 3.16Å; A51-V55 WeakPolarHBondContact O-CG2 3.28Å; A51-V55 PolarHBondContact O-N 3.32Å; A51-V260 HydrophobicContact CB-CG1 4.13Å; A51-M264 HydrophobicContact CB-CG 4.05Å; A51-M264 HydrophobicContact CB-SD 3.96Å; A51-V275 HydrophobicContact CB-CG1 3.82Å; A51-V275 HydrophobicContact CB-CG2 4.21Å
52	V	91.2	Very high	80.6	Confident	8 Å²	8	43 Å²	43	5%	0.048	26%	0.262	C	S	.	.	H	α-helix	trans	-57.3	-50.9	171.9	171.4	0	0	0	0	110.3	A48 L49 G50 I54 V55 V56 V275 C278 S279 I282	A48-V52 WeakPolarHBondContact O-CG2 3.45Å; A48-V52 PolarHBondContact O-N 3.01Å; L49-V52 WeakPolarHBondContact O-CB 3.2Å; L49-V52 PolarHBondContact O-N 3.36Å; G50-V52 VanDerWaalsContact C-N 3.34Å; V52-I54 VanDerWaalsContact C-N 3.28Å; V52-I54 PolarHBondContact O-N 2.96Å; V52-V55 PolarHBondContact O-N 2.9Å; V52-V56 HydrophobicContact CG1-CG2 3.99Å; V52-V56 WeakPolarHBondContact O-CB 3.39Å; V52-V56 WeakPolarHBondContact O-CG2 3.23Å; V52-V56 PolarHBondContact O-N 2.72Å; V52-V275 HydrophobicContact CG2-CB 4.22Å; V52-V275 HydrophobicContact CG2-CG1 4.01Å; V52-V275 HydrophobicContact CG2-CG2 4.22Å; V52-C278 HydrophobicContact CG2-CB 4.34Å; V52-S279 WeakPolarHBondContact CA-OG 3.16Å; V52-S279 PolarHBondContact O-OG 2.72Å; V52-I282 HydrophobicContact CG1-CD1 3.96Å
53	F	87.6	Confident	82.8	Confident	94 Å²	94	39.5 Å²	39.5	41%	0.412	23%	0.226	S	C	.	.	H	α-helix	trans	-60.3	-37.2	178.6	-75.6	-74.2	0	0	0	113.2	L49 G50 N57 V204	L49-F53 WeakPolarHBondContact O-CD2 3.42Å; L49-F53 PolarHBondContact O-N 3.23Å; G50-F53 PolarHBondContact O-N 3.39Å; F53-N57 WeakPolarHBondContact O-CB 3.42Å; F53-N57 PolarHBondContact O-N 3.31Å; F53-V204 HydrophobicContact CD1-CB 4.33Å; F53-V204 HydrophobicContact CD1-CG1 4.33Å; F53-V204 HydrophobicContact CD1-CG2 4.25Å; F53-V204 HydrophobicContact CE1-CG1 4.35Å
54	I	86.4	Confident	84.9	Confident	15 Å²	15	34.9 Å²	34.9	8%	0.077	19%	0.194	C	C	.	.	H	α-helix	trans	-69	-43.6	177.9	-62.8	167.4	0	0	0	111	V46 G50 A51 V52 N57 A58 V260	V46-I54 HydrophobicContact CG1-CD1 3.97Å; V46-I54 HydrophobicContact CG2-CD1 4.4Å; G50-I54 WeakPolarHBondContact O-CG1 3.39Å; G50-I54 PolarHBondContact O-N 3.45Å; G50-I54 VanDerWaalsContact O-N 3.09Å; A51-I54 PolarHBondContact O-N 3.16Å; V52-I54 VanDerWaalsContact C-N 3.28Å; V52-I54 PolarHBondContact O-N 2.96Å; I54-N57 PolarHBondContact O-N 2.63Å; I54-A58 WeakPolarHBondContact O-CB 3.37Å; I54-A58 PolarHBondContact O-N 2.87Å; I54-V260 HydrophobicContact CG2-CG1 4.38Å; I54-V260 HydrophobicContact CG2-CG2 3.55Å
55	V	89.8	Confident	86.3	Confident	4 Å²	4	22.9 Å²	22.9	2%	0.024	15%	0.148	C	C	.	.	H	α-helix	trans	-67.2	-43.2	177.6	174.9	0	0	0	0	111	A51 V52 A58 A59 V260 W272 V275 M280	A51-V55 WeakPolarHBondContact O-CG2 3.28Å; A51-V55 PolarHBondContact O-N 3.32Å; V52-V55 PolarHBondContact O-N 2.9Å; V55-A58 PolarHBondContact O-N 3.48Å; V55-A59 PolarHBondContact O-N 2.79Å; V55-V260 HydrophobicContact CG2-CG1 3.98Å; V55-W272 HydrophobicContact CG2-CH2 4.27Å; V55-W272 HydrophobicContact CG2-CZ3 4.46Å; V55-V275 HydrophobicContact CG2-CG1 4.23Å; V55-M280 HydrophobicContact CG1-CE 3.62Å
56	V	90.5	Very high	87.3	Confident	1 Å²	1	21.5 Å²	21.5	1%	0.006	13%	0.134	C	C	.	.	H	α-helix	trans	-60.7	-45.7	175.1	175.3	0	0	0	0	110.2	V52 A58 A59 L60 V204 I282	V52-V56 HydrophobicContact CG1-CG2 3.99Å; V52-V56 WeakPolarHBondContact O-CB 3.39Å; V52-V56 WeakPolarHBondContact O-CG2 3.23Å; V52-V56 PolarHBondContact O-N 2.72Å; V56-A58 VanDerWaalsContact C-N 3.3Å; V56-A58 PolarHBondContact O-N 3.26Å; V56-A59 PolarHBondContact O-N 3.49Å; V56-A59 VanDerWaalsContact O-N 3.16Å; V56-L60 HydrophobicContact CG1-CD1 3.31Å; V56-L60 HydrophobicContact CG1-CG 3.74Å; V56-L60 WeakPolarHBondContact O-CB 3.28Å; V56-L60 WeakPolarHBondContact O-CG 3.46Å; V56-L60 PolarHBondContact O-N 3.45Å; V56-V204 HydrophobicContact CB-CG2 4.15Å; V56-V204 HydrophobicContact CG1-CG1 4.19Å; V56-V204 HydrophobicContact CG1-CG2 3.66Å; V56-I282 HydrophobicContact CG1-CG2 4.06Å; V56-I282 HydrophobicContact CG2-CB 4.24Å; V56-I282 HydrophobicContact CG2-CD1 4.24Å; V56-I282 HydrophobicContact CG2-CG2 4.27Å
57	N	86.5	Confident	87.8	Confident	3 Å²	3	19.6 Å²	19.6	2%	0.016	12%	0.122	C	C	.	.	H	α-helix	trans	-62.5	-36.8	176	-179.8	75	0	0	0	112.8	F53 I54 A59 S200 S203 V204	F53-N57 WeakPolarHBondContact O-CB 3.42Å; F53-N57 PolarHBondContact O-N 3.31Å; I54-N57 PolarHBondContact O-N 2.63Å; N57-A59 VanDerWaalsContact C-N 3.27Å; N57-A59 PolarHBondContact O-N 3.47Å; N57-S200 PolarHBondContact ND2-OG 3.26Å; N57-S203 WeakPolarHBondContact OD1-CB 3.27Å; N57-S203 PolarHBondContact OD1-OG 2.91Å; N57-V204 HydrophobicContact CB-CG2 4.37Å
58	A	86.2	Confident	88.1	Confident	33 Å²	33	16.7 Å²	16.7	27%	0.273	10%	0.102	S	C	.	.	H	α-helix	trans	-66.7	-30.2	176.7	0	0	0	0	0	112.3	I54 V55 V56 C253	I54-A58 WeakPolarHBondContact O-CB 3.37Å; I54-A58 PolarHBondContact O-N 2.87Å; V55-A58 PolarHBondContact O-N 3.48Å; V56-A58 VanDerWaalsContact C-N 3.3Å; V56-A58 PolarHBondContact O-N 3.26Å; A58-C253 HydrophobicContact CB-CB 3.88Å
59	A	89.6	Confident	88.2	Confident	5 Å²	5	14.9 Å²	14.9	4%	0.041	9%	0.087	C	C	.	.	H	α-helix	trans	-83.7	-58.1	174.9	0	0	0	0	0	112.1	V55 V56 N57 G61 C253 M280 Y287	V55-A59 PolarHBondContact O-N 2.79Å; V56-A59 PolarHBondContact O-N 3.49Å; V56-A59 VanDerWaalsContact O-N 3.16Å; N57-A59 VanDerWaalsContact C-N 3.27Å; N57-A59 PolarHBondContact O-N 3.47Å; A59-G61 PolarHBondContact O-N 2.81Å; A59-C253 HydrophobicContact CB-CB 4.27Å; A59-M280 HydrophobicContact CB-CE 4.49Å; A59-Y287 PolarHBondContact O-OH 2.67Å
60	L	85.6	Confident	88.4	Confident	0 Å²	0	9.3 Å²	9.3	0%	0	6%	0.058	C	C	.	.	S	Bend	trans	-66.9	15.8	-170.6	-70	-171.2	0	0	0	116.5	V56 T207 C283 V286 Y287	V56-L60 HydrophobicContact CG1-CD1 3.31Å; V56-L60 HydrophobicContact CG1-CG 3.74Å; V56-L60 WeakPolarHBondContact O-CB 3.28Å; V56-L60 WeakPolarHBondContact O-CG 3.46Å; V56-L60 PolarHBondContact O-N 3.45Å; L60-T207 HydrophobicContact CB-CG2 4Å; L60-T207 WeakPolarHBondContact CD1-OG1 3.31Å; L60-T207 WeakPolarHBondContact O-CG2 3.24Å; L60-C283 HydrophobicContact CD2-CB 4.04Å; L60-V286 HydrophobicContact CD1-CB 4.42Å; L60-V286 HydrophobicContact CD1-CG1 4.15Å; L60-V286 HydrophobicContact CD1-CG2 4.2Å; L60-V286 HydrophobicContact CD2-CB 3.92Å; L60-V286 HydrophobicContact CD2-CG1 3.45Å; L60-V286 VanDerWaalsContact CD2-CG1 3.45Å; L60-V286 HydrophobicContact CG-CG1 4.45Å; L60-Y287 VanDerWaalsContact CA-OH 3.32Å; L60-Y287 WeakPolarHBondContact CA-OH 3.33Å; L60-Y287 HydrophobicContact CD2-CD1 4.25Å; L60-Y287 HydrophobicContact CD2-CE1 3.63Å; L60-Y287 HydrophobicContact CD2-CE2 4.15Å; L60-Y287 PolarHBondContact N-OH 3.02Å
61	G	75.1	Confident	88.8	Confident	7 Å²	7	8.5 Å²	8.5	7%	0.072	5%	0.05	C	C	.	.	S	Bend	trans	-62.9	-149.2	-179.1	0	0	0	0	0	114	A59 G63 L64	A59-G61 PolarHBondContact O-N 2.81Å; G61-G63 PolarHBondContact O-N 2.9Å; G61-L64 PolarHBondContact O-N 2.91Å
62	A	77.9	Confident	88.9	Confident	1 Å²	1	9.4 Å²	9.4	1%	0.008	6%	0.056	C	C	.	.	G	3₁₀ helix	trans	-53.3	-25	178.7	0	0	0	0	0	114.6	L64 L65 N66 F141 V144 V328	A62-L64 PolarHBondContact O-N 3.48Å; A62-L64 VanDerWaalsContact O-N 3.14Å; A62-L65 WeakPolarHBondContact O-CB 3.25Å; A62-L65 PolarHBondContact O-N 3.27Å; A62-N66 PolarHBondContact O-OD1 3.39Å; A62-F141 HydrophobicContact CB-CD1 4.13Å; A62-F141 HydrophobicContact CB-CE1 3.99Å; A62-V144 HydrophobicContact CB-CG1 4.49Å; A62-V144 HydrophobicContact CB-CG2 3.93Å; A62-V328 HydrophobicContact CB-CG2 3.98Å
63	G	83.9	Confident	88.8	Confident	3 Å²	3	11.8 Å²	11.8	3%	0.031	7%	0.067	C	C	.	.	G	3₁₀ helix	trans	-61.5	-19.7	-178.5	0	0	0	0	0	115.3	G61 L65 N66 F67	G61-G63 PolarHBondContact O-N 2.9Å; G63-L65 PolarHBondContact O-N 2.96Å; G63-N66 PolarHBondContact O-N 3.49Å; G63-F67 VanDerWaalsContact O-CD2 3.22Å; G63-F67 WeakPolarHBondContact O-CD2 3.41Å; G63-F67 WeakPolarHBondContact O-CE2 3.48Å
64	L	91.7	Very high	88.9	Confident	0 Å²	0	7.3 Å²	7.3	0%	0	5%	0.047	C	C	.	.	G	3₁₀ helix	trans	-54.5	-39.9	172.7	174.7	61.5	0	0	0	112.5	G61 A62 N66 F67 T207 V210 V286 Y287 T290	G61-L64 PolarHBondContact O-N 2.91Å; A62-L64 PolarHBondContact O-N 3.48Å; A62-L64 VanDerWaalsContact O-N 3.14Å; L64-N66 PolarHBondContact O-N 3.41Å; L64-N66 VanDerWaalsContact O-N 3.17Å; L64-F67 PolarHBondContact O-N 3.33Å; L64-T207 HydrophobicContact CD2-CG2 4.4Å; L64-V210 HydrophobicContact CD2-CB 4.38Å; L64-V210 HydrophobicContact CD2-CG1 4.14Å; L64-V286 HydrophobicContact CD1-CG1 3.55Å; L64-V286 HydrophobicContact CD2-CG1 4.09Å; L64-V286 HydrophobicContact CG-CG1 4.46Å; L64-Y287 HydrophobicContact CB-CD1 4.35Å; L64-Y287 HydrophobicContact CB-CE1 3.87Å; L64-Y287 HydrophobicContact CD1-CD1 3.42Å; L64-Y287 VanDerWaalsContact CD1-CD1 3.42Å; L64-Y287 HydrophobicContact CD1-CE1 3.77Å; L64-Y287 HydrophobicContact CG-CE1 4.45Å; L64-T290 HydrophobicContact CD1-CG2 3.93Å; L64-T290 WeakPolarHBondContact CD1-OG1 3.26Å; L64-T290 HydrophobicContact CG-CG2 4.23Å
65	L	92.2	Very high	89	Confident	0 Å²	0	7 Å²	7	0%	0	5%	0.049	C	C	.	.	G	3₁₀ helix	trans	-67.5	-19.7	-171	-56.5	175.4	0	0	0	112.7	A62 G63 V144 V210 D305 V306 L307 I324	A62-L65 WeakPolarHBondContact O-CB 3.25Å; A62-L65 PolarHBondContact O-N 3.27Å; G63-L65 PolarHBondContact O-N 2.96Å; L65-V144 HydrophobicContact CD1-CG1 4.17Å; L65-V210 HydrophobicContact CD2-CG1 4.25Å; L65-D305 WeakPolarHBondContact CD1-OD2 3.41Å; L65-V306 HydrophobicContact CD2-CG1 4.34Å; L65-V306 PolarHBondContact O-N 3.48Å; L65-L307 HydrophobicContact CD2-CD1 3.72Å; L65-L307 HydrophobicContact CD2-CG 3.86Å; L65-I324 HydrophobicContact CD1-CD1 4.33Å; L65-I324 HydrophobicContact CD1-CG1 4.35Å; L65-I324 HydrophobicContact CD1-CG2 3.78Å; L65-I324 HydrophobicContact CD2-CD1 3.92Å; L65-I324 HydrophobicContact CD2-CG1 4.08Å; L65-I324 HydrophobicContact CG-CD1 4.33Å
66	N	93.4	Very high	88.9	Confident	1 Å²	1	7 Å²	7	1%	0.005	5%	0.05	C	C	.	.	G	3₁₀ helix	trans	-95.9	-7.8	-174	-55.8	75.6	0	0	0	113.9	A62 G63 L64 A69 A70 T246 Q304 I391	A62-N66 PolarHBondContact O-OD1 3.39Å; G63-N66 PolarHBondContact O-N 3.49Å; L64-N66 PolarHBondContact O-N 3.41Å; L64-N66 VanDerWaalsContact O-N 3.17Å; N66-A69 PolarHBondContact O-N 2.91Å; N66-A70 PolarHBondContact O-N 3.01Å; N66-T246 HydrophobicContact CB-CG2 3.44Å; N66-T246 VanDerWaalsContact CB-CG2 3.44Å; N66-Q304 WeakPolarHBondContact CA-O 3.21Å; N66-Q304 PolarHBondContact ND2-O 3.18Å; N66-I391 WeakPolarHBondContact ND2-CD1 3.23Å
67	F	94.6	Very high	89	Confident	0 Å²	0	8.8 Å²	8.8	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-60.7	-41.8	-178.9	-86.7	-100.9	0	0	0	113.7	G63 L64 A69 A70 F71 I247 F251 Y287	G63-F67 VanDerWaalsContact O-CD2 3.22Å; G63-F67 WeakPolarHBondContact O-CD2 3.41Å; G63-F67 WeakPolarHBondContact O-CE2 3.48Å; L64-F67 PolarHBondContact O-N 3.33Å; F67-A69 VanDerWaalsContact C-N 3.34Å; F67-A69 PolarHBondContact O-N 3.44Å; F67-A70 WeakPolarHBondContact O-CB 3.39Å; F67-A70 PolarHBondContact O-N 2.75Å; F67-F71 HydrophobicContact CD1-CE1 4.26Å; F67-F71 VanDerWaalsContact O-CD1 3.29Å; F67-F71 WeakPolarHBondContact O-CD1 3.33Å; F67-F71 PolarHBondContact O-N 3.07Å; F67-I247 HydrophobicContact CE1-CG1 4.41Å; F67-F251 HydrophobicContact CE1-CD2 4.35Å; F67-F251 AromaticContact CE1-CE2 3.83Å; F67-F251 HydrophobicContact CE1-CE2 3.83Å; F67-F251 AromaticContact CZ-CD2 3.84Å; F67-F251 HydrophobicContact CZ-CD2 3.84Å; F67-F251 AromaticContact CZ-CE2 3.69Å; F67-F251 HydrophobicContact CZ-CE2 3.69Å; F67-Y287 HydrophobicContact CD1-CD1 4.35Å; F67-Y287 HydrophobicContact CD1-CG 4.09Å; F67-Y287 AromaticContact CD2-CD1 3.48Å; F67-Y287 HydrophobicContact CD2-CD1 3.48Å; F67-Y287 VanDerWaalsContact CD2-CD1 3.48Å; F67-Y287 AromaticContact CD2-CE1 3.94Å; F67-Y287 HydrophobicContact CD2-CE1 3.94Å; F67-Y287 AromaticContact CD2-CG 4Å; F67-Y287 HydrophobicContact CD2-CG 4Å; F67-Y287 HydrophobicContact CE1-CD1 4.15Å; F67-Y287 AromaticContact CE1-CD2 3.96Å; F67-Y287 HydrophobicContact CE1-CD2 3.96Å; F67-Y287 AromaticContact CE1-CG 3.64Å; F67-Y287 HydrophobicContact CE1-CG 3.64Å; F67-Y287 AromaticContact CE2-CD1 3.23Å; F67-Y287 HydrophobicContact CE2-CD1 3.23Å; F67-Y287 AromaticContact CE2-CD2 3.92Å; F67-Y287 HydrophobicContact CE2-CD2 3.92Å; F67-Y287 AromaticContact CE2-CE1 3.41Å; F67-Y287 HydrophobicContact CE2-CE1 3.41Å; F67-Y287 VanDerWaalsContact CE2-CE1 3.41Å; F67-Y287 AromaticContact CE2-CE2 3.98Å; F67-Y287 HydrophobicContact CE2-CE2 3.98Å; F67-Y287 AromaticContact CE2-CG 3.54Å; F67-Y287 HydrophobicContact CE2-CG 3.54Å; F67-Y287 AromaticContact CE2-CZ 3.75Å; F67-Y287 HydrophobicContact CG-CD1 4.04Å; F67-Y287 HydrophobicContact CG-CG 4.25Å; F67-Y287 AromaticContact CZ-CD1 3.61Å; F67-Y287 HydrophobicContact CZ-CD1 3.61Å; F67-Y287 AromaticContact CZ-CD2 3.43Å; F67-Y287 HydrophobicContact CZ-CD2 3.43Å; F67-Y287 VanDerWaalsContact CZ-CD2 3.43Å; F67-Y287 AromaticContact CZ-CE1 3.99Å; F67-Y287 HydrophobicContact CZ-CE1 3.99Å; F67-Y287 AromaticContact CZ-CE2 3.74Å; F67-Y287 HydrophobicContact CZ-CE2 3.74Å; F67-Y287 AromaticContact CZ-CG 3.34Å; F67-Y287 HydrophobicContact CZ-CG 3.34Å
68	P	94.8	Very high	89.2	Confident	0 Å²	0	16.1 Å²	16.1	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-57.4	-45.2	173.4	-31.5	41.5	0	0	0	113	F71 S72 T290 V302 V306	P68-F71 PolarHBondContact O-N 2.94Å; P68-S72 PolarHBondContact O-N 3.46Å; P68-T290 HydrophobicContact CG-CG2 4.26Å; P68-T290 WeakPolarHBondContact CG-O 3.24Å; P68-V302 HydrophobicContact CB-CG1 4.48Å; P68-V302 HydrophobicContact CB-CG2 3.67Å; P68-V306 HydrophobicContact CB-CB 4.32Å; P68-V306 HydrophobicContact CB-CG2 4.11Å; P68-V306 HydrophobicContact CG-CB 3.85Å; P68-V306 HydrophobicContact CG-CG1 4.33Å; P68-V306 HydrophobicContact CG-CG2 3.78Å
69	A	92.4	Very high	89.5	Confident	2 Å²	2	15.5 Å²	15.5	2%	0.017	9%	0.091	C	C	.	.	H	α-helix	trans	-65.1	-38	175.6	0	0	0	0	0	112.1	N66 F67 F71 S72 M73 V302	N66-A69 PolarHBondContact O-N 2.91Å; F67-A69 VanDerWaalsContact C-N 3.34Å; F67-A69 PolarHBondContact O-N 3.44Å; A69-F71 VanDerWaalsContact C-N 3.3Å; A69-F71 PolarHBondContact O-N 3.28Å; A69-S72 WeakPolarHBondContact O-CB 3.48Å; A69-S72 PolarHBondContact O-N 3.5Å; A69-M73 WeakPolarHBondContact O-CB 3.32Å; A69-M73 WeakPolarHBondContact O-CG 3.36Å; A69-M73 PolarHBondContact O-N 3.41Å; A69-V302 HydrophobicContact CB-CG1 4.12Å
70	A	92.9	Very high	89.6	Confident	1 Å²	1	15.3 Å²	15.3	1%	0.008	9%	0.089	C	C	.	.	H	α-helix	trans	-62.2	-37.5	173.5	0	0	0	0	0	112.2	N66 F67 M73 A74 A243 T246 I247	N66-A70 PolarHBondContact O-N 3.01Å; F67-A70 WeakPolarHBondContact O-CB 3.39Å; F67-A70 PolarHBondContact O-N 2.75Å; A70-M73 HydrophobicContact CB-CE 4.48Å; A70-M73 PolarHBondContact O-N 2.83Å; A70-A74 VanDerWaalsContact O-CB 3.31Å; A70-A74 WeakPolarHBondContact O-CB 3.32Å; A70-A74 PolarHBondContact O-N 3.12Å; A70-A243 VanDerWaalsContact O-CB 3.29Å; A70-A243 WeakPolarHBondContact O-CB 3.44Å; A70-T246 HydrophobicContact CB-CG2 3.89Å; A70-I247 HydrophobicContact CB-CG1 4.26Å
71	F	93.3	Very high	90.1	Very high	0 Å²	0	17 Å²	17	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-71.2	-38.4	177.9	-78.9	25.9	0	0	0	111	F67 P68 A69 A74 G75 G76 V81 V292 F295	F67-F71 HydrophobicContact CD1-CE1 4.26Å; F67-F71 VanDerWaalsContact O-CD1 3.29Å; F67-F71 WeakPolarHBondContact O-CD1 3.33Å; F67-F71 PolarHBondContact O-N 3.07Å; P68-F71 PolarHBondContact O-N 2.94Å; A69-F71 VanDerWaalsContact C-N 3.3Å; A69-F71 PolarHBondContact O-N 3.28Å; F71-A74 PolarHBondContact O-N 3.26Å; F71-G75 PolarHBondContact O-N 3.33Å; F71-G76 WeakPolarHBondContact O-CA 3.26Å; F71-G76 PolarHBondContact O-N 3Å; F71-V81 HydrophobicContact CE2-CG2 3.8Å; F71-V81 HydrophobicContact CZ-CG2 4.03Å; F71-V292 HydrophobicContact CE2-CG2 3.86Å; F71-F295 HydrophobicContact CB-CB 4.07Å; F71-F295 HydrophobicContact CB-CD2 4.31Å; F71-F295 HydrophobicContact CB-CG 4.12Å
72	S	90.9	Very high	91	Very high	19 Å²	19	23 Å²	23	13%	0.133	13%	0.127	C	C	.	.	H	α-helix	trans	-58	-51.4	169.8	178.8	0	0	0	0	111.2	P68 A69 A74 G75 S300	P68-S72 PolarHBondContact O-N 3.46Å; A69-S72 WeakPolarHBondContact O-CB 3.48Å; A69-S72 PolarHBondContact O-N 3.5Å; S72-A74 VanDerWaalsContact C-N 3.28Å; S72-A74 PolarHBondContact O-N 3.44Å; S72-G75 PolarHBondContact O-N 2.9Å; S72-G75 VanDerWaalsContact O-N 3.08Å; S72-S300 WeakPolarHBondContact OG-CA 3.38Å
73	M	89.1	Confident	91.7	Very high	58 Å²	58	23.3 Å²	23.3	29%	0.286	13%	0.129	S	C	.	.	H	α-helix	trans	-61.2	-34	177.3	-72.1	-173.1	-68.6	0	0	113.1	A69 A70 G75 A239 A243	A69-M73 WeakPolarHBondContact O-CB 3.32Å; A69-M73 WeakPolarHBondContact O-CG 3.36Å; A69-M73 PolarHBondContact O-N 3.41Å; A70-M73 HydrophobicContact CB-CE 4.48Å; A70-M73 PolarHBondContact O-N 2.83Å; M73-G75 PolarHBondContact O-N 2.79Å; M73-A239 CarbonylContact O-C 3.56Å; M73-A239 VanDerWaalsContact O-CB 3.28Å; M73-A239 WeakPolarHBondContact O-CB 3.45Å; M73-A243 HydrophobicContact CB-CB 4.11Å
74	A	90.2	Very high	92.2	Very high	0 Å²	0	23.2 Å²	23.2	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-73.5	-11.2	178.8	0	0	0	0	0	113.7	A70 F71 S72 A79 A243	A70-A74 VanDerWaalsContact O-CB 3.31Å; A70-A74 WeakPolarHBondContact O-CB 3.32Å; A70-A74 PolarHBondContact O-N 3.12Å; F71-A74 PolarHBondContact O-N 3.26Å; S72-A74 VanDerWaalsContact C-N 3.28Å; S72-A74 PolarHBondContact O-N 3.44Å; A74-A79 HydrophobicContact CB-CB 4.17Å; A74-A79 VanDerWaalsContact O-CB 3.26Å; A74-A79 WeakPolarHBondContact O-CB 3.41Å; A74-A243 HydrophobicContact CB-CB 3.86Å
75	G	87.4	Confident	92.4	Very high	10 Å²	10	27.2 Å²	27.2	10%	0.103	15%	0.147	C	C	.	.	T	Hydrogen-bonded Turn	trans	91.5	24.6	-175.3	0	0	0	0	0	114.1	F71 S72 M73 T233	F71-G75 PolarHBondContact O-N 3.33Å; S72-G75 PolarHBondContact O-N 2.9Å; S72-G75 VanDerWaalsContact O-N 3.08Å; M73-G75 PolarHBondContact O-N 2.79Å; G75-T233 VanDerWaalsContact CA-O 3.22Å; G75-T233 WeakPolarHBondContact CA-O 3.43Å
76	G	89.4	Confident	92.5	Very high	4 Å²	4	31.5 Å²	31.5	4%	0.041	17%	0.166	C	C	.	.	S	Bend	trans	117.5	-179.6	169.1	0	0	0	0	0	115.3	F71 M78 A79 G80	F71-G76 WeakPolarHBondContact O-CA 3.26Å; F71-G76 PolarHBondContact O-N 3Å; G76-M78 PolarHBondContact O-N 3.44Å; G76-A79 PolarHBondContact O-N 3.37Å; G76-G80 PolarHBondContact O-N 3.3Å
77	V	91.1	Very high	92.5	Very high	38 Å²	38	31.5 Å²	31.5	23%	0.23	17%	0.166	C	C	.	.	H	α-helix	trans	-54.5	-49.3	-173.4	174.5	0	0	0	0	113.1	A79 G80 V81 V292 F295 L296	V77-A79 PolarHBondContact O-N 3.19Å; V77-G80 PolarHBondContact O-N 3.12Å; V77-V81 HydrophobicContact CG1-CG2 4.13Å; V77-V81 WeakPolarHBondContact O-CB 3.43Å; V77-V81 WeakPolarHBondContact O-CG2 3.32Å; V77-V81 PolarHBondContact O-N 3.17Å; V77-V292 HydrophobicContact CG1-CG1 4.14Å; V77-V292 HydrophobicContact CG1-CG2 3.85Å; V77-V292 HydrophobicContact CG2-CG1 4.41Å; V77-F295 HydrophobicContact CG2-CD1 3.48Å; V77-F295 VanDerWaalsContact CG2-CD1 3.48Å; V77-F295 HydrophobicContact CG2-CE1 4.03Å; V77-F295 HydrophobicContact CG2-CG 4.49Å; V77-L296 HydrophobicContact CG2-CD2 3.87Å; V77-L296 HydrophobicContact CG2-CG 4Å
78	M	91.3	Very high	92.5	Very high	157 Å²	157	32.2 Å²	32.2	77%	0.773	17%	0.17	S	C	*	.	H	α-helix	trans	-64.5	-43.1	-174.7	-175.4	132.8	60.3	0	0	111.7	G76 M82	G76-M78 PolarHBondContact O-N 3.44Å; M78-M82 WeakPolarHBondContact O-CB 3.27Å; M78-M82 WeakPolarHBondContact O-CG 3.48Å; M78-M82 PolarHBondContact O-N 2.89Å
79	A	92	Very high	92.5	Very high	20 Å²	20	37.2 Å²	37.2	17%	0.165	20%	0.195	C	C	.	.	H	α-helix	trans	-65.2	-44.5	176.1	0	0	0	0	0	111.4	A74 G76 V77 M82 L83 A235 V240	A74-A79 HydrophobicContact CB-CB 4.17Å; A74-A79 VanDerWaalsContact O-CB 3.26Å; A74-A79 WeakPolarHBondContact O-CB 3.41Å; G76-A79 PolarHBondContact O-N 3.37Å; V77-A79 PolarHBondContact O-N 3.19Å; A79-M82 PolarHBondContact O-N 3.4Å; A79-L83 WeakPolarHBondContact O-CB 3.22Å; A79-L83 PolarHBondContact O-N 2.98Å; A79-A235 HydrophobicContact CB-CB 4.25Å; A79-V240 HydrophobicContact CB-CG2 4.36Å
80	G	92.9	Very high	92.7	Very high	0 Å²	0	37.9 Å²	37.9	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-60.1	-48.5	177.5	0	0	0	0	0	113.4	G76 V77 L83 Q84	G76-G80 PolarHBondContact O-N 3.3Å; V77-G80 PolarHBondContact O-N 3.12Å; G80-L83 PolarHBondContact O-N 3.32Å; G80-Q84 WeakPolarHBondContact O-CB 3.4Å; G80-Q84 PolarHBondContact O-N 2.89Å
81	V	94.8	Very high	92.8	Very high	36 Å²	36	37.9 Å²	37.9	22%	0.218	20%	0.198	C	C	.	.	H	α-helix	trans	-65.5	-45.3	178.7	173.2	0	0	0	0	111.3	F71 V77 L83 Q84 M85 I288 V292	F71-V81 HydrophobicContact CE2-CG2 3.8Å; F71-V81 HydrophobicContact CZ-CG2 4.03Å; V77-V81 HydrophobicContact CG1-CG2 4.13Å; V77-V81 WeakPolarHBondContact O-CB 3.43Å; V77-V81 WeakPolarHBondContact O-CG2 3.32Å; V77-V81 PolarHBondContact O-N 3.17Å; V81-L83 VanDerWaalsContact C-N 3.32Å; V81-L83 PolarHBondContact O-N 3.43Å; V81-Q84 PolarHBondContact O-N 2.77Å; V81-M85 HydrophobicContact CG1-CG 4.36Å; V81-M85 VanDerWaalsContact O-CG 3.31Å; V81-M85 WeakPolarHBondContact O-CG 3.45Å; V81-M85 PolarHBondContact O-N 2.81Å; V81-I288 HydrophobicContact CG1-CD1 4.35Å; V81-V292 HydrophobicContact CG2-CG2 4.04Å
82	M	94.1	Very high	93	Very high	133 Å²	133	39.7 Å²	39.7	66%	0.655	21%	0.207	S	C	*	.	H	α-helix	trans	-62	-42.5	177.7	-73	-65.8	-118.6	0	0	111.6	M78 A79 M85 F86	M78-M82 WeakPolarHBondContact O-CB 3.27Å; M78-M82 WeakPolarHBondContact O-CG 3.48Å; M78-M82 PolarHBondContact O-N 2.89Å; A79-M82 PolarHBondContact O-N 3.4Å; M82-M85 PolarHBondContact O-N 2.72Å; M82-F86 WeakPolarHBondContact O-CB 3.44Å; M82-F86 PolarHBondContact O-N 3.44Å
83	L	93.6	Very high	93.2	Very high	8 Å²	8	40.2 Å²	40.2	4%	0.042	21%	0.211	C	C	.	.	H	α-helix	trans	-60.8	-46.7	175.6	175.4	57.9	0	0	0	111.2	A79 G80 V81 M85 F86 M87 V240 A243 M244 I247	A79-L83 WeakPolarHBondContact O-CB 3.22Å; A79-L83 PolarHBondContact O-N 2.98Å; G80-L83 PolarHBondContact O-N 3.32Å; V81-L83 VanDerWaalsContact C-N 3.32Å; V81-L83 PolarHBondContact O-N 3.43Å; L83-M85 PolarHBondContact O-N 3.33Å; L83-F86 PolarHBondContact O-N 3.02Å; L83-M87 HydrophobicContact CD1-CE 4.1Å; L83-M87 HydrophobicContact CD1-CG 3.88Å; L83-M87 HydrophobicContact CD1-SD 4.44Å; L83-M87 HydrophobicContact CG-CG 4.32Å; L83-M87 WeakPolarHBondContact O-CB 3.35Å; L83-M87 WeakPolarHBondContact O-CG 3.24Å; L83-M87 PolarHBondContact O-N 3.24Å; L83-V240 HydrophobicContact CB-CG1 4.39Å; L83-V240 HydrophobicContact CD1-CG1 4.06Å; L83-V240 HydrophobicContact CD2-CG1 3.96Å; L83-V240 WeakPolarHBondContact CD2-O 3.4Å; L83-V240 HydrophobicContact CG-CG1 4.36Å; L83-A243 HydrophobicContact CD2-CB 4.14Å; L83-M244 HydrophobicContact CD1-CE 3.43Å; L83-M244 VanDerWaalsContact CD1-CE 3.43Å; L83-M244 HydrophobicContact CD1-CG 3.77Å; L83-M244 HydrophobicContact CD1-SD 4.28Å; L83-M244 HydrophobicContact CD2-CG 3.95Å; L83-M244 HydrophobicContact CG-CG 4.43Å; L83-I247 HydrophobicContact CB-CD1 4.37Å; L83-I247 HydrophobicContact CD2-CD1 3.48Å; L83-I247 VanDerWaalsContact CD2-CD1 3.48Å; L83-I247 HydrophobicContact CG-CD1 3.68Å
84	Q	94.3	Very high	93.6	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-60.7	-46	178.5	-175.1	173	11.6	0	0	112.2	G80 V81 F86 M87 L88 F251 L284 I288	G80-Q84 WeakPolarHBondContact O-CB 3.4Å; G80-Q84 PolarHBondContact O-N 2.89Å; V81-Q84 PolarHBondContact O-N 2.77Å; Q84-F86 VanDerWaalsContact C-N 3.33Å; Q84-F86 PolarHBondContact O-N 2.62Å; Q84-M87 PolarHBondContact O-N 3Å; Q84-L88 WeakPolarHBondContact O-CB 3.4Å; Q84-L88 PolarHBondContact O-N 3.19Å; Q84-F251 HydrophobicContact CG-CE2 3.77Å; Q84-F251 HydrophobicContact CG-CZ 4.02Å; Q84-F251 VanDerWaalsContact NE2-CZ 3.34Å; Q84-L284 HydrophobicContact CG-CD1 3.9Å; Q84-I288 VanDerWaalsContact OE1-CG1 3.28Å
85	M	95.1	Very high	93.9	Very high	85 Å²	85	37.4 Å²	37.4	42%	0.419	20%	0.197	S	C	.	.	H	α-helix	trans	-61.6	-41.5	177.2	-70.3	-57.5	-63.9	0	0	111.9	V81 M82 L83 L88 L284	V81-M85 HydrophobicContact CG1-CG 4.36Å; V81-M85 VanDerWaalsContact O-CG 3.31Å; V81-M85 WeakPolarHBondContact O-CG 3.45Å; V81-M85 PolarHBondContact O-N 2.81Å; M82-M85 PolarHBondContact O-N 2.72Å; L83-M85 PolarHBondContact O-N 3.33Å; M85-L88 PolarHBondContact O-N 3.18Å; M85-L284 HydrophobicContact SD-CD1 3.88Å; M85-L284 HydrophobicContact SD-CD2 3.82Å; M85-L284 HydrophobicContact SD-CG 4.44Å
86	F	94.3	Very high	94.4	Very high	90 Å²	90	39 Å²	39	40%	0.395	21%	0.205	S	C	.	.	H	α-helix	trans	-63.7	-47.7	176.1	174.4	-105.9	0	0	0	111.9	M82 L83 Q84 L88 I89 F90 L438	M82-F86 WeakPolarHBondContact O-CB 3.44Å; M82-F86 PolarHBondContact O-N 3.44Å; L83-F86 PolarHBondContact O-N 3.02Å; Q84-F86 VanDerWaalsContact C-N 3.33Å; Q84-F86 PolarHBondContact O-N 2.62Å; F86-L88 VanDerWaalsContact C-N 3.29Å; F86-L88 PolarHBondContact O-N 3.24Å; F86-I89 PolarHBondContact O-N 3.22Å; F86-F90 HydrophobicContact CD1-CE2 4.37Å; F86-F90 HydrophobicContact CD2-CE2 4.18Å; F86-F90 HydrophobicContact CE1-CD2 4.49Å; F86-F90 AromaticContact CE1-CE2 3.86Å; F86-F90 HydrophobicContact CE1-CE2 3.86Å; F86-F90 AromaticContact CE2-CE2 3.65Å; F86-F90 HydrophobicContact CE2-CE2 3.65Å; F86-F90 HydrophobicContact CE2-CZ 4.24Å; F86-F90 HydrophobicContact CZ-CD2 4.48Å; F86-F90 AromaticContact CZ-CE2 3.47Å; F86-F90 HydrophobicContact CZ-CE2 3.47Å; F86-F90 VanDerWaalsContact CZ-CE2 3.47Å; F86-F90 HydrophobicContact CZ-CZ 4.08Å; F86-F90 WeakPolarHBondContact O-CD2 3.5Å; F86-L438 HydrophobicContact CE1-CD2 3.92Å; F86-L438 HydrophobicContact CZ-CD2 4.08Å
87	M	94.2	Very high	94.7	Very high	1 Å²	1	39.6 Å²	39.6	1%	0.005	21%	0.207	C	C	.	.	H	α-helix	trans	-62.9	-35.6	178.3	-65.7	-78.6	113.6	0	0	111.9	L83 Q84 I89 F90 I91 M244 I247 F403 L438 I442	L83-M87 HydrophobicContact CD1-CE 4.1Å; L83-M87 HydrophobicContact CD1-CG 3.88Å; L83-M87 HydrophobicContact CD1-SD 4.44Å; L83-M87 HydrophobicContact CG-CG 4.32Å; L83-M87 WeakPolarHBondContact O-CB 3.35Å; L83-M87 WeakPolarHBondContact O-CG 3.24Å; L83-M87 PolarHBondContact O-N 3.24Å; Q84-M87 PolarHBondContact O-N 3Å; M87-I89 VanDerWaalsContact C-N 3.26Å; M87-I89 PolarHBondContact O-N 3.38Å; M87-F90 PolarHBondContact O-N 3.4Å; M87-F90 VanDerWaalsContact O-N 3.08Å; M87-I91 HydrophobicContact CB-CD1 4.15Å; M87-I91 WeakPolarHBondContact O-CD1 3.31Å; M87-I91 WeakPolarHBondContact O-CG1 3.06Å; M87-I91 PolarHBondContact O-N 3.49Å; M87-M244 HydrophobicContact CE-CE 3.86Å; M87-M244 HydrophobicContact CE-SD 3.84Å; M87-M244 HydrophobicContact SD-CG 4.49Å; M87-M244 HydrophobicContact SD-SD 4.39Å; M87-I247 HydrophobicContact CB-CG2 4.4Å; M87-I247 HydrophobicContact CG-CG2 4.37Å; M87-F403 HydrophobicContact CE-CE1 4.47Å; M87-F403 HydrophobicContact CE-CZ 4.01Å; M87-F403 HydrophobicContact SD-CE1 4.44Å; M87-F403 HydrophobicContact SD-CE2 4.1Å; M87-F403 HydrophobicContact SD-CZ 3.48Å; M87-F403 WeakPolarHBondContact SD-CZ 3.23Å; M87-L438 HydrophobicContact CE-CD2 4.26Å; M87-I442 HydrophobicContact CE-CD1 4.28Å
88	L	94.8	Very high	94.9	Very high	15 Å²	15	37.8 Å²	37.8	8%	0.079	20%	0.196	C	C	.	.	H	α-helix	trans	-58.4	-36.4	-177.8	-166	69.1	0	0	0	112.9	Q84 M85 F86 F90 I91 I92 F251 M280 L284	Q84-L88 WeakPolarHBondContact O-CB 3.4Å; Q84-L88 PolarHBondContact O-N 3.19Å; M85-L88 PolarHBondContact O-N 3.18Å; F86-L88 VanDerWaalsContact C-N 3.29Å; F86-L88 PolarHBondContact O-N 3.24Å; L88-F90 VanDerWaalsContact C-N 3.31Å; L88-F90 PolarHBondContact O-N 2.96Å; L88-I91 PolarHBondContact O-N 3.43Å; L88-I92 HydrophobicContact CD1-CD1 4.49Å; L88-I92 HydrophobicContact CD2-CD1 4.44Å; L88-I92 HydrophobicContact CG-CD1 3.97Å; L88-I92 HydrophobicContact CG-CG1 4.48Å; L88-I92 WeakPolarHBondContact O-CG1 3.28Å; L88-I92 PolarHBondContact O-N 2.89Å; L88-F251 HydrophobicContact CD1-CD1 4.46Å; L88-F251 HydrophobicContact CD1-CE1 3.78Å; L88-F251 HydrophobicContact CD1-CZ 4.15Å; L88-M280 HydrophobicContact CD1-CB 3.94Å; L88-L284 HydrophobicContact CD2-CB 4.38Å; L88-L284 HydrophobicContact CD2-CD1 4.13Å; L88-L284 HydrophobicContact CD2-CD2 3.82Å; L88-L284 HydrophobicContact CD2-CG 4.33Å
89	I	94.9	Very high	95	Very high	104 Å²	104	30.3 Å²	30.3	53%	0.533	16%	0.159	S	C	.	.	H	α-helix	trans	-58.7	-46.6	177.2	-61.5	170.2	0	0	0	109.9	F86 M87 S93	F86-I89 PolarHBondContact O-N 3.22Å; M87-I89 VanDerWaalsContact C-N 3.26Å; M87-I89 PolarHBondContact O-N 3.38Å; I89-S93 VanDerWaalsContact O-CB 3.25Å; I89-S93 WeakPolarHBondContact O-CB 3.25Å; I89-S93 PolarHBondContact O-N 3.47Å; I89-S93 PolarHBondContact O-OG 3.18Å
90	F	95.7	Very high	95.2	Very high	16 Å²	16	33.9 Å²	33.9	7%	0.07	17%	0.169	C	C	.	.	H	α-helix	trans	-74.4	-35.6	-179.6	-63.5	-74.6	0	0	0	112.7	F86 M87 L88 S93 G94 F403 L431 T434 M435 L438	F86-F90 HydrophobicContact CD1-CE2 4.37Å; F86-F90 HydrophobicContact CD2-CE2 4.18Å; F86-F90 HydrophobicContact CE1-CD2 4.49Å; F86-F90 AromaticContact CE1-CE2 3.86Å; F86-F90 HydrophobicContact CE1-CE2 3.86Å; F86-F90 AromaticContact CE2-CE2 3.65Å; F86-F90 HydrophobicContact CE2-CE2 3.65Å; F86-F90 HydrophobicContact CE2-CZ 4.24Å; F86-F90 HydrophobicContact CZ-CD2 4.48Å; F86-F90 AromaticContact CZ-CE2 3.47Å; F86-F90 HydrophobicContact CZ-CE2 3.47Å; F86-F90 VanDerWaalsContact CZ-CE2 3.47Å; F86-F90 HydrophobicContact CZ-CZ 4.08Å; F86-F90 WeakPolarHBondContact O-CD2 3.5Å; M87-F90 PolarHBondContact O-N 3.4Å; M87-F90 VanDerWaalsContact O-N 3.08Å; L88-F90 VanDerWaalsContact C-N 3.31Å; L88-F90 PolarHBondContact O-N 2.96Å; F90-S93 PolarHBondContact O-N 3.33Å; F90-G94 PolarHBondContact O-N 3.44Å; F90-F403 HydrophobicContact CB-CD1 3.8Å; F90-F403 HydrophobicContact CB-CE1 3.24Å; F90-F403 HydrophobicContact CB-CZ 3.99Å; F90-F403 HydrophobicContact CD1-CD1 4.34Å; F90-F403 HydrophobicContact CD1-CE1 4.2Å; F90-F403 AromaticContact CD2-CE1 3.73Å; F90-F403 HydrophobicContact CD2-CE1 3.73Å; F90-F403 HydrophobicContact CG-CD1 4.02Å; F90-F403 AromaticContact CG-CE1 3.47Å; F90-F403 HydrophobicContact CG-CE1 3.47Å; F90-F403 VanDerWaalsContact CG-CE1 3.47Å; F90-F403 HydrophobicContact CG-CZ 4.48Å; F90-L431 HydrophobicContact CD1-CD1 4.5Å; F90-L431 HydrophobicContact CE1-CD1 4.2Å; F90-T434 HydrophobicContact CE1-CG2 4.35Å; F90-T434 HydrophobicContact CZ-CG2 4.39Å; F90-M435 HydrophobicContact CB-CE 4.33Å; F90-M435 HydrophobicContact CD1-CE 4.42Å; F90-M435 HydrophobicContact CD1-CG 3.59Å; F90-M435 HydrophobicContact CD1-SD 4.34Å; F90-M435 HydrophobicContact CE1-CG 4.01Å; F90-L438 HydrophobicContact CD2-CD2 4.3Å; F90-L438 HydrophobicContact CE2-CD2 3.95Å; F90-L438 HydrophobicContact CZ-CD2 4.12Å
91	I	96.2	Very high	95.2	Very high	2 Å²	2	34 Å²	34	1%	0.01	17%	0.169	C	C	.	.	H	α-helix	trans	-58.4	-54	174.5	-73.3	157.7	0	0	0	110.5	M87 L88 S93 G94 L95 F251 H254 M280 I402	M87-I91 HydrophobicContact CB-CD1 4.15Å; M87-I91 WeakPolarHBondContact O-CD1 3.31Å; M87-I91 WeakPolarHBondContact O-CG1 3.06Å; M87-I91 PolarHBondContact O-N 3.49Å; L88-I91 PolarHBondContact O-N 3.43Å; I91-S93 VanDerWaalsContact C-N 3.34Å; I91-S93 PolarHBondContact O-N 3.05Å; I91-G94 PolarHBondContact O-N 3.35Å; I91-L95 HydrophobicContact CG2-CD1 4.12Å; I91-L95 WeakPolarHBondContact O-CG 3.31Å; I91-L95 PolarHBondContact O-N 3.45Å; I91-L95 VanDerWaalsContact O-N 3.07Å; I91-F251 HydrophobicContact CD1-CB 3.4Å; I91-F251 VanDerWaalsContact CD1-CB 3.4Å; I91-F251 HydrophobicContact CD1-CD1 4.01Å; I91-F251 HydrophobicContact CD1-CD2 3.98Å; I91-F251 HydrophobicContact CD1-CG 3.56Å; I91-F251 HydrophobicContact CG1-CB 4.21Å; I91-H254 PolarHBondContact O-NE2 3.46Å; I91-M280 HydrophobicContact CG2-CG 4.12Å; I91-M280 HydrophobicContact CG2-SD 3.49Å; I91-M280 WeakPolarHBondContact CG2-SD 3.44Å; I91-I402 HydrophobicContact CG1-CD1 4.43Å; I91-I402 HydrophobicContact CG1-CG2 3.7Å
92	I	96.4	Very high	95	Very high	37 Å²	37	32.3 Å²	32.3	19%	0.19	16%	0.159	C	C	.	.	H	α-helix	trans	-61.8	-45.4	178.9	-67.8	170.4	0	0	0	110	L88 G94 L95 V96 V276 M280	L88-I92 HydrophobicContact CD1-CD1 4.49Å; L88-I92 HydrophobicContact CD2-CD1 4.44Å; L88-I92 HydrophobicContact CG-CD1 3.97Å; L88-I92 HydrophobicContact CG-CG1 4.48Å; L88-I92 WeakPolarHBondContact O-CG1 3.28Å; L88-I92 PolarHBondContact O-N 2.89Å; I92-G94 PolarHBondContact O-N 2.95Å; I92-L95 PolarHBondContact O-N 3.23Å; I92-V96 HydrophobicContact CG2-CG2 4.48Å; I92-V96 WeakPolarHBondContact O-CG2 3.2Å; I92-V96 PolarHBondContact O-N 2.88Å; I92-V276 HydrophobicContact CG2-CG1 4.22Å; I92-M280 HydrophobicContact CD1-CB 3.98Å; I92-M280 HydrophobicContact CD1-CG 4.48Å; I92-M280 HydrophobicContact CG1-CB 3.75Å; I92-M280 HydrophobicContact CG1-CG 3.7Å
93	S	96	Very high	94.9	Very high	30 Å²	30	30.4 Å²	30.4	21%	0.21	15%	0.149	C	C	.	.	H	α-helix	trans	-58.8	-48.2	178.7	-61.9	0	0	0	0	111.5	I89 F90 I91 L95 V96 I97	I89-S93 VanDerWaalsContact O-CB 3.25Å; I89-S93 WeakPolarHBondContact O-CB 3.25Å; I89-S93 PolarHBondContact O-N 3.47Å; I89-S93 PolarHBondContact O-OG 3.18Å; F90-S93 PolarHBondContact O-N 3.33Å; I91-S93 VanDerWaalsContact C-N 3.34Å; I91-S93 PolarHBondContact O-N 3.05Å; S93-L95 PolarHBondContact O-N 3.33Å; S93-V96 PolarHBondContact O-N 3.02Å; S93-I97 WeakPolarHBondContact O-CB 3.46Å; S93-I97 VanDerWaalsContact O-CD1 3.3Å; S93-I97 WeakPolarHBondContact O-CD1 3.36Å; S93-I97 WeakPolarHBondContact O-CG1 3.45Å; S93-I97 PolarHBondContact O-N 2.93Å
94	G	96.8	Very high	94.7	Very high	0 Å²	0	32.8 Å²	32.8	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-59.8	-43.3	178.5	0	0	0	0	0	113	F90 I91 I92 I97 L98	F90-G94 PolarHBondContact O-N 3.44Å; I91-G94 PolarHBondContact O-N 3.35Å; I92-G94 PolarHBondContact O-N 2.95Å; G94-I97 PolarHBondContact O-N 3.34Å; G94-L98 WeakPolarHBondContact O-CB 3.29Å; G94-L98 WeakPolarHBondContact O-CD1 3.4Å; G94-L98 VanDerWaalsContact O-CG 3.27Å; G94-L98 WeakPolarHBondContact O-CG 3.35Å; G94-L98 PolarHBondContact O-N 3.34Å
95	L	96.8	Very high	94.4	Very high	0 Å²	0	34 Å²	34	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-64.4	-39.5	176.7	-70.2	169	0	0	0	112.4	I91 I92 S93 G99 H254 C257 W272 V276 M280	I91-L95 HydrophobicContact CG2-CD1 4.12Å; I91-L95 WeakPolarHBondContact O-CG 3.31Å; I91-L95 PolarHBondContact O-N 3.45Å; I91-L95 VanDerWaalsContact O-N 3.07Å; I92-L95 PolarHBondContact O-N 3.23Å; S93-L95 PolarHBondContact O-N 3.33Å; L95-G99 PolarHBondContact O-N 3.37Å; L95-G99 VanDerWaalsContact O-N 3.14Å; L95-H254 HydrophobicContact CD2-CB 4.22Å; L95-C257 HydrophobicContact CD2-CB 3.46Å; L95-C257 VanDerWaalsContact CD2-CB 3.46Å; L95-W272 PolarHBondContact O-NE1 2.91Å; L95-V276 HydrophobicContact CB-CB 4.38Å; L95-V276 HydrophobicContact CB-CG1 3.55Å; L95-V276 HydrophobicContact CB-CG2 3.88Å; L95-V276 HydrophobicContact CD1-CG1 3.59Å; L95-V276 HydrophobicContact CD1-CG2 4.47Å; L95-V276 HydrophobicContact CG-CG1 4.21Å; L95-M280 HydrophobicContact CD1-CE 3.79Å; L95-M280 HydrophobicContact CD1-CG 4.12Å; L95-M280 HydrophobicContact CD1-SD 4.04Å
96	V	96.8	Very high	94	Very high	43 Å²	43	36.7 Å²	36.7	26%	0.261	19%	0.194	S	C	.	.	H	α-helix	trans	-69.4	-43.3	176.4	172.6	0	0	0	0	111.1	I92 S93 L98 G99 Y100 I269 V276	I92-V96 HydrophobicContact CG2-CG2 4.48Å; I92-V96 WeakPolarHBondContact O-CG2 3.2Å; I92-V96 PolarHBondContact O-N 2.88Å; S93-V96 PolarHBondContact O-N 3.02Å; V96-L98 PolarHBondContact O-N 3.43Å; V96-G99 PolarHBondContact O-N 3.43Å; V96-Y100 PolarHBondContact O-N 3.35Å; V96-I269 HydrophobicContact CG1-CG2 4.32Å; V96-V276 HydrophobicContact CG2-CG1 4.49Å
97	I	96.4	Very high	93.6	Very high	16 Å²	16	35.5 Å²	35.5	8%	0.082	19%	0.19	C	C	.	.	H	α-helix	trans	-59.4	-47.5	177.2	-68.7	158.4	0	0	0	110.5	S93 G94 G99 Y100 C101 P406 C409 L410 M435	S93-I97 WeakPolarHBondContact O-CB 3.46Å; S93-I97 VanDerWaalsContact O-CD1 3.3Å; S93-I97 WeakPolarHBondContact O-CD1 3.36Å; S93-I97 WeakPolarHBondContact O-CG1 3.45Å; S93-I97 PolarHBondContact O-N 2.93Å; G94-I97 PolarHBondContact O-N 3.34Å; I97-G99 VanDerWaalsContact C-N 3.32Å; I97-G99 PolarHBondContact O-N 3.23Å; I97-Y100 WeakPolarHBondContact O-CB 3.36Å; I97-Y100 PolarHBondContact O-N 2.98Å; I97-Y100 VanDerWaalsContact O-N 3.13Å; I97-C101 PolarHBondContact O-N 3.45Å; I97-C101 PolarHBondContact O-SG 3.48Å; I97-C101 VanDerWaalsContact O-SG 3.38Å; I97-P406 HydrophobicContact CB-CB 4.47Å; I97-P406 HydrophobicContact CG2-CB 4.35Å; I97-P406 WeakPolarHBondContact CG2-O 3.25Å; I97-C409 HydrophobicContact CG2-CB 4.35Å; I97-L410 HydrophobicContact CD1-CB 4.1Å; I97-L410 HydrophobicContact CD1-CD2 3.72Å; I97-L410 HydrophobicContact CD1-CG 4.38Å; I97-L410 HydrophobicContact CG1-CB 4.37Å; I97-L410 HydrophobicContact CG1-CD1 4.38Å; I97-L410 HydrophobicContact CG1-CD2 4.28Å; I97-L410 HydrophobicContact CG2-CB 3.95Å; I97-M435 HydrophobicContact CD1-SD 3.92Å
98	L	95.6	Very high	93	Very high	0 Å²	0	36.5 Å²	36.5	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-63.1	-38.7	178.3	-72.3	165.8	0	0	0	112.4	G94 V96 Y100 C101 S102 Y110 H254 V258 P406	G94-L98 WeakPolarHBondContact O-CB 3.29Å; G94-L98 WeakPolarHBondContact O-CD1 3.4Å; G94-L98 VanDerWaalsContact O-CG 3.27Å; G94-L98 WeakPolarHBondContact O-CG 3.35Å; G94-L98 PolarHBondContact O-N 3.34Å; V96-L98 PolarHBondContact O-N 3.43Å; L98-Y100 VanDerWaalsContact C-N 3.33Å; L98-C101 PolarHBondContact O-N 3.33Å; L98-S102 VanDerWaalsContact O-CB 3.23Å; L98-S102 WeakPolarHBondContact O-CB 3.4Å; L98-S102 PolarHBondContact O-N 3.02Å; L98-Y110 HydrophobicContact CD1-CD2 3.93Å; L98-Y110 HydrophobicContact CD1-CE2 3.31Å; L98-Y110 HydrophobicContact CD2-CD2 4.18Å; L98-Y110 HydrophobicContact CD2-CE2 3.8Å; L98-Y110 HydrophobicContact CG-CE2 4.2Å; L98-H254 HydrophobicContact CD1-CB 3.96Å; L98-V258 HydrophobicContact CB-CG2 4.13Å; L98-P406 HydrophobicContact CD1-CG 3.94Å; L98-P406 HydrophobicContact CD2-CG 4.36Å; L98-P406 HydrophobicContact CG-CB 4.3Å; L98-P406 HydrophobicContact CG-CG 4.04Å
99	G	94.3	Very high	92.5	Very high	0 Å²	0	36.7 Å²	36.7	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-62.9	-40.3	172.8	0	0	0	0	0	112.3	L95 V96 I97 Q103 I269	L95-G99 PolarHBondContact O-N 3.37Å; L95-G99 VanDerWaalsContact O-N 3.14Å; V96-G99 PolarHBondContact O-N 3.43Å; I97-G99 VanDerWaalsContact C-N 3.32Å; I97-G99 PolarHBondContact O-N 3.23Å; G99-Q103 PolarHBondContact O-N 3.03Å; G99-I269 WeakPolarHBondContact O-CD1 3.41Å
100	Y	94.9	Very high	92.3	Very high	96 Å²	96	31.8 Å²	31.8	38%	0.376	18%	0.175	S	C	.	.	H	α-helix	trans	-63.2	-50.8	174.3	175.3	-97.2	0	0	0	112.1	V96 I97 L98 S102 Q103 A104 I269 A413	V96-Y100 PolarHBondContact O-N 3.35Å; I97-Y100 WeakPolarHBondContact O-CB 3.36Å; I97-Y100 PolarHBondContact O-N 2.98Å; I97-Y100 VanDerWaalsContact O-N 3.13Å; L98-Y100 VanDerWaalsContact C-N 3.33Å; Y100-S102 VanDerWaalsContact C-N 3.32Å; Y100-S102 PolarHBondContact O-N 3.33Å; Y100-Q103 PolarHBondContact O-N 3.4Å; Y100-A104 WeakPolarHBondContact O-CB 3.47Å; Y100-A104 PolarHBondContact O-N 3.07Å; Y100-I269 HydrophobicContact CD2-CG1 4.36Å; Y100-A413 HydrophobicContact CE1-CB 4.43Å
101	C	93.4	Very high	92	Very high	2 Å²	2	31.9 Å²	31.9	1%	0.014	18%	0.176	C	C	.	.	H	α-helix	trans	-63.4	-38.7	178.8	-65.9	0	0	0	0	111.6	I97 L98 Q103 A104 S105 V113	I97-C101 PolarHBondContact O-N 3.45Å; I97-C101 PolarHBondContact O-SG 3.48Å; I97-C101 VanDerWaalsContact O-SG 3.38Å; L98-C101 PolarHBondContact O-N 3.33Å; C101-Q103 PolarHBondContact O-N 3.06Å; C101-A104 PolarHBondContact O-N 2.94Å; C101-S105 WeakPolarHBondContact O-CB 3.33Å; C101-S105 PolarHBondContact O-N 3.49Å; C101-S105 PolarHBondContact O-OG 3.31Å; C101-V113 HydrophobicContact CB-CG1 3.47Å; C101-V113 VanDerWaalsContact CB-CG1 3.47Å
102	S	91.3	Very high	91.6	Very high	1 Å²	1	32.6 Å²	32.6	1%	0.007	18%	0.179	C	C	.	.	H	α-helix	trans	-60	-43.9	173	176.6	0	0	0	0	112.7	L98 Y100 N106 E107 N262	L98-S102 VanDerWaalsContact O-CB 3.23Å; L98-S102 WeakPolarHBondContact O-CB 3.4Å; L98-S102 PolarHBondContact O-N 3.02Å; Y100-S102 VanDerWaalsContact C-N 3.32Å; Y100-S102 PolarHBondContact O-N 3.33Å; S102-N106 WeakPolarHBondContact O-CA 3.38Å; S102-N106 PolarHBondContact O-N 3.01Å; S102-E107 PolarHBondContact O-N 3.08Å; S102-E107 PolarHBondContact OG-O 2.97Å; S102-N262 PolarHBondContact OG-ND2 3.44Å
103	Q	92.2	Very high	91.3	Very high	93 Å²	93	30.9 Å²	30.9	44%	0.435	17%	0.17	S	C	.	.	H	α-helix	trans	-66.4	-39.1	175.6	-170.4	177	21.2	0	0	112	G99 Y100 C101 F261 K267 I269	G99-Q103 PolarHBondContact O-N 3.03Å; Y100-Q103 PolarHBondContact O-N 3.4Å; C101-Q103 PolarHBondContact O-N 3.06Å; Q103-F261 HydrophobicContact CB-CE1 4.12Å; Q103-F261 HydrophobicContact CB-CZ 4.08Å; Q103-K267 PolarHBondContact NE2-O 2.93Å; Q103-I269 HydrophobicContact CB-CD1 4.21Å; Q103-I269 VanDerWaalsContact OE1-CD1 3.28Å
104	A	89.4	Confident	91.3	Very high	57 Å²	57	29.4 Å²	29.4	47%	0.471	16%	0.16	S	C	.	.	H	α-helix	trans	-73	-38.3	-177.7	0	0	0	0	0	113	Y100 C101	Y100-A104 WeakPolarHBondContact O-CB 3.47Å; Y100-A104 PolarHBondContact O-N 3.07Å; C101-A104 PolarHBondContact O-N 2.94Å
105	S	87.8	Confident	91	Very high	27 Å²	27	30.9 Å²	30.9	19%	0.189	17%	0.166	C	C	.	.	H	α-helix	trans	-89.1	-9.9	179	73.8	0	0	0	0	113.4	C101 E107	C101-S105 WeakPolarHBondContact O-CB 3.33Å; C101-S105 PolarHBondContact O-N 3.49Å; C101-S105 PolarHBondContact O-OG 3.31Å; S105-E107 PolarHBondContact O-N 3.48Å; S105-E107 WeakPolarHBondContact OG-CB 3.36Å; S105-E107 WeakPolarHBondContact OG-CG 3.37Å; S105-E107 PolarHBondContact OG-N 2.76Å
106	N	86.4	Confident	90.7	Very high	141 Å²	141	33.8 Å²	33.8	75%	0.754	19%	0.189	S	C	*	.	T	Hydrogen-bonded Turn	trans	57.1	31.5	-172.9	-165	53.3	0	0	0	113.6	S102	S102-N106 WeakPolarHBondContact O-CA 3.38Å; S102-N106 PolarHBondContact O-N 3.01Å
107	E	85.8	Confident	90.5	Very high	64 Å²	64	33.3 Å²	33.3	30%	0.299	19%	0.186	S	C	.	.			trans	-102	142.5	-179.1	-69.1	-63.8	168.4	0	0	112	S102 S105 E112 V113 A116 N262	S102-E107 PolarHBondContact O-N 3.08Å; S102-E107 PolarHBondContact OG-O 2.97Å; S105-E107 PolarHBondContact O-N 3.48Å; S105-E107 WeakPolarHBondContact OG-CB 3.36Å; S105-E107 WeakPolarHBondContact OG-CG 3.37Å; S105-E107 PolarHBondContact OG-N 2.76Å; E107-E112 HydrophobicContact CB-CB 4.11Å; E107-E112 HydrophobicContact CG-CB 4.09Å; E107-E112 WeakPolarHBondContact OE2-CB 3.35Å; E107-V113 HydrophobicContact CB-CG2 3.68Å; E107-A116 HydrophobicContact CG-CB 4.11Å; E107-N262 PolarHBondContact O-ND2 3.43Å
108	A	81.3	Confident	90.3	Very high	22 Å²	22	33.5 Å²	33.5	18%	0.182	19%	0.189	C	C	.	.			trans	-101.9	-3.6	-169.9	0	0	0	0	0	115.1	N262	A108-N262 HydrophobicContact CB-CB 4.45Å
109	T	84.9	Confident	90.1	Very high	20 Å²	20	35.1 Å²	35.1	12%	0.123	21%	0.205	C	C	.	.	S	Bend	trans	-131.9	154.2	-179.7	66.6	0	0	0	0	111.6	Q111 E112 V113	T109-Q111 PolarHBondContact O-N 3.32Å; T109-Q111 PolarHBondContact OG1-NE2 2.91Å; T109-Q111 VanDerWaalsContact OG1-NE2 3.14Å; T109-E112 PolarHBondContact O-N 3.27Å; T109-E112 WeakPolarHBondContact OG1-CB 3.33Å; T109-E112 WeakPolarHBondContact OG1-CG 3.25Å; T109-V113 VanDerWaalsContact O-CG2 3.31Å; T109-V113 WeakPolarHBondContact O-CG2 3.47Å; T109-V113 PolarHBondContact O-N 3.39Å; T109-V113 VanDerWaalsContact O-N 3.08Å
110	Y	89.3	Confident	89.8	Confident	1 Å²	1	41 Å²	41	0%	0.004	23%	0.231	C	C	.	.	H	α-helix	trans	-56.8	-50.9	-176.1	-172.9	-75.2	0	0	0	112.3	L98 E112 V113 V114 C126 I130 H254 V258 F401 F405	L98-Y110 HydrophobicContact CD1-CD2 3.93Å; L98-Y110 HydrophobicContact CD1-CE2 3.31Å; L98-Y110 HydrophobicContact CD2-CD2 4.18Å; L98-Y110 HydrophobicContact CD2-CE2 3.8Å; L98-Y110 HydrophobicContact CG-CE2 4.2Å; Y110-E112 VanDerWaalsContact C-N 3.35Å; Y110-E112 PolarHBondContact O-N 2.91Å; Y110-V113 PolarHBondContact O-N 3Å; Y110-V114 HydrophobicContact CD1-CG2 3.96Å; Y110-V114 HydrophobicContact CE1-CG2 3.67Å; Y110-V114 WeakPolarHBondContact O-CG2 3.48Å; Y110-V114 PolarHBondContact O-N 3.49Å; Y110-V114 VanDerWaalsContact O-N 3.07Å; Y110-C126 WeakPolarHBondContact CD1-SG 3.17Å; Y110-C126 WeakPolarHBondContact CE1-SG 3.34Å; Y110-I130 HydrophobicContact CD1-CD1 3.74Å; Y110-I130 HydrophobicContact CE1-CD1 4.49Å; Y110-I130 HydrophobicContact CG-CD1 4.2Å; Y110-H254 WeakPolarHBondContact CD2-O 3.33Å; Y110-H254 HydrophobicContact CE2-CB 3.95Å; Y110-V258 HydrophobicContact CD2-CG2 4.46Å; Y110-F401 HydrophobicContact CE1-CD1 4.16Å; Y110-F401 VanDerWaalsContact OH-CA 3.25Å; Y110-F401 WeakPolarHBondContact OH-CA 3.25Å; Y110-F401 PolarHBondContact OH-O 3.41Å; Y110-F405 HydrophobicContact CE1-CB 4.13Å; Y110-F405 HydrophobicContact CE1-CD2 4.2Å; Y110-F405 HydrophobicContact CE1-CG 4.32Å; Y110-F405 VanDerWaalsContact OH-CB 3.29Å; Y110-F405 WeakPolarHBondContact OH-CB 3.3Å
111	Q	89.8	Confident	89.6	Confident	18 Å²	18	41.8 Å²	41.8	8%	0.084	25%	0.245	C	C	.	.	H	α-helix	trans	-63.9	-37.6	-177.1	61.3	-79	-0	0	0	113.2	T109 V114 R115 E127 I130 V342	T109-Q111 PolarHBondContact O-N 3.32Å; T109-Q111 PolarHBondContact OG1-NE2 2.91Å; T109-Q111 VanDerWaalsContact OG1-NE2 3.14Å; Q111-V114 PolarHBondContact O-N 2.87Å; Q111-R115 VanDerWaalsContact O-CB 3.28Å; Q111-R115 WeakPolarHBondContact O-CB 3.33Å; Q111-R115 PolarHBondContact O-N 3.21Å; Q111-E127 HydrophobicContact CB-CG 3.54Å; Q111-E127 HydrophobicContact CG-CG 3.76Å; Q111-I130 HydrophobicContact CB-CD1 4.29Å; Q111-V342 HydrophobicContact CG-CG2 4.36Å
112	E	87.9	Confident	89.6	Confident	17 Å²	17	43.2 Å²	43.2	8%	0.079	25%	0.254	C	S	.	.	H	α-helix	trans	-72.4	-35.5	179.2	-62.4	-58.8	157.5	0	0	110.9	G20 E107 T109 Y110 V114 R115 A116 R349	G20-E112 VanDerWaalsContact CA-OE1 3.28Å; G20-E112 WeakPolarHBondContact CA-OE1 3.45Å; E107-E112 HydrophobicContact CB-CB 4.11Å; E107-E112 HydrophobicContact CG-CB 4.09Å; E107-E112 WeakPolarHBondContact OE2-CB 3.35Å; T109-E112 PolarHBondContact O-N 3.27Å; T109-E112 WeakPolarHBondContact OG1-CB 3.33Å; T109-E112 WeakPolarHBondContact OG1-CG 3.25Å; Y110-E112 VanDerWaalsContact C-N 3.35Å; Y110-E112 PolarHBondContact O-N 2.91Å; E112-V114 PolarHBondContact O-N 3.41Å; E112-R115 PolarHBondContact O-N 2.64Å; E112-R115 WeakPolarHBondContact OE2-CD 3.23Å; E112-A116 VanDerWaalsContact O-CB 3.26Å; E112-A116 WeakPolarHBondContact O-CB 3.29Å; E112-A116 PolarHBondContact O-N 3.02Å; E112-R349 IonicContact OE1-CZ 2.82Å; E112-R349 IonicContact OE1-NH2 3.04Å; E112-R349 PolarHBondContact OE1-NH2 3.1Å; E112-R349 IonicContact OE2-NH2 2.9Å; E112-R349 PolarHBondContact OE2-NH2 2.98Å
113	V	91	Very high	89.5	Confident	0 Å²	0	43.1 Å²	43.1	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-59	-48.1	170.8	172.7	0	0	0	0	111.3	C101 E107 T109 Y110 R115 A116 T117 V258	C101-V113 HydrophobicContact CB-CG1 3.47Å; C101-V113 VanDerWaalsContact CB-CG1 3.47Å; E107-V113 HydrophobicContact CB-CG2 3.68Å; T109-V113 VanDerWaalsContact O-CG2 3.31Å; T109-V113 WeakPolarHBondContact O-CG2 3.47Å; T109-V113 PolarHBondContact O-N 3.39Å; T109-V113 VanDerWaalsContact O-N 3.08Å; Y110-V113 PolarHBondContact O-N 3Å; V113-R115 VanDerWaalsContact C-N 3.32Å; V113-R115 PolarHBondContact O-N 3.49Å; V113-A116 PolarHBondContact O-N 3.44Å; V113-T117 WeakPolarHBondContact O-CB 3.36Å; V113-T117 PolarHBondContact O-N 2.94Å; V113-T117 PolarHBondContact O-OG1 3.48Å; V113-V258 HydrophobicContact CG2-CG1 3.83Å; V113-V258 HydrophobicContact CG2-CG2 4.38Å
114	V	94.5	Very high	89.4	Confident	0 Å²	0	41.2 Å²	41.2	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-63.5	-40.9	177.8	174.3	0	0	0	0	110.7	Y110 Q111 E112 T117 C118 T122 C126 F405	Y110-V114 HydrophobicContact CD1-CG2 3.96Å; Y110-V114 HydrophobicContact CE1-CG2 3.67Å; Y110-V114 WeakPolarHBondContact O-CG2 3.48Å; Y110-V114 PolarHBondContact O-N 3.49Å; Y110-V114 VanDerWaalsContact O-N 3.07Å; Q111-V114 PolarHBondContact O-N 2.87Å; E112-V114 PolarHBondContact O-N 3.41Å; V114-T117 PolarHBondContact O-N 2.72Å; V114-C118 HydrophobicContact CG1-CB 4.41Å; V114-C118 WeakPolarHBondContact O-CA 3.33Å; V114-C118 VanDerWaalsContact O-CB 3.24Å; V114-C118 WeakPolarHBondContact O-CB 3.33Å; V114-C118 PolarHBondContact O-N 3.01Å; V114-T122 HydrophobicContact CG1-CG2 3.76Å; V114-C126 HydrophobicContact CB-CB 4.34Å; V114-C126 HydrophobicContact CG1-CB 4.02Å; V114-F405 HydrophobicContact CG1-CD1 3.9Å; V114-F405 HydrophobicContact CG1-CE1 4.5Å; V114-F405 HydrophobicContact CG2-CB 4.05Å; V114-F405 HydrophobicContact CG2-CG 4.46Å
115	R	91.5	Very high	89.7	Confident	31 Å²	31	43.3 Å²	43.3	12%	0.117	25%	0.251	C	S	.	.	H	α-helix	trans	-65.2	-45.4	178.6	-171.9	-180	179.5	87.1	-10.7	112.5	S16 Q111 E112 V113 T117 G119 K120 R349	S16-R115 PolarHBondContact O-NH2 2.78Å; Q111-R115 VanDerWaalsContact O-CB 3.28Å; Q111-R115 WeakPolarHBondContact O-CB 3.33Å; Q111-R115 PolarHBondContact O-N 3.21Å; E112-R115 PolarHBondContact O-N 2.64Å; E112-R115 WeakPolarHBondContact OE2-CD 3.23Å; V113-R115 VanDerWaalsContact C-N 3.32Å; V113-R115 PolarHBondContact O-N 3.49Å; R115-T117 VanDerWaalsContact C-N 3.32Å; R115-G119 CarbonylContact O-C 3.48Å; R115-G119 WeakPolarHBondContact O-CA 3.4Å; R115-G119 PolarHBondContact O-N 3.39Å; R115-K120 PolarHBondContact NH1-O 3.16Å; R115-R349 VanDerWaalsContact CD-NH2 3.32Å; R115-R349 VanDerWaalsContact CZ-NH1 3.33Å
116	A	89.8	Confident	89.9	Confident	60 Å²	60	42 Å²	42	50%	0.496	24%	0.242	S	C	.	.	H	α-helix	trans	-65.7	-36.9	179.3	0	0	0	0	0	111.6	E107 E112 V113	E107-A116 HydrophobicContact CG-CB 4.11Å; E112-A116 VanDerWaalsContact O-CB 3.26Å; E112-A116 WeakPolarHBondContact O-CB 3.29Å; E112-A116 PolarHBondContact O-N 3.02Å; V113-A116 PolarHBondContact O-N 3.44Å
117	T	92.2	Very high	90.2	Very high	33 Å²	33	35.4 Å²	35.4	20%	0.202	21%	0.206	C	C	.	.	H	α-helix	trans	-87.5	-40.4	-176	-46.5	0	0	0	0	112.9	V113 V114 R115 C409 Q412	V113-T117 WeakPolarHBondContact O-CB 3.36Å; V113-T117 PolarHBondContact O-N 2.94Å; V113-T117 PolarHBondContact O-OG1 3.48Å; V114-T117 PolarHBondContact O-N 2.72Å; R115-T117 VanDerWaalsContact C-N 3.32Å; T117-C409 HydrophobicContact CG2-CB 4.16Å; T117-Q412 HydrophobicContact CG2-CB 4.1Å; T117-Q412 WeakPolarHBondContact O-CB 3.47Å
118	C	92.9	Very high	90.5	Very high	21 Å²	21	37 Å²	37	14%	0.142	22%	0.215	C	C	.	.	H	α-helix	trans	-112	3.9	-170.9	-57	0	0	0	0	113.9	V114 T122 C409	V114-C118 HydrophobicContact CG1-CB 4.41Å; V114-C118 WeakPolarHBondContact O-CA 3.33Å; V114-C118 VanDerWaalsContact O-CB 3.24Å; V114-C118 WeakPolarHBondContact O-CB 3.33Å; V114-C118 PolarHBondContact O-N 3.01Å; C118-T122 HydrophobicContact CB-CG2 3.75Å; C118-T122 PolarHBondContact O-OG1 2.93Å; C118-T122 VanDerWaalsContact O-OG1 3.07Å; C118-C409 VanDerWaalsContact SG-SG 3.69Å
119	G	91.3	Very high	91.2	Very high	33 Å²	33	36.6 Å²	36.6	34%	0.34	21%	0.212	S	C	.	.			trans	87.7	173.2	178	0	0	0	0	0	115.1	R115 V121 G123	R115-G119 CarbonylContact O-C 3.48Å; R115-G119 WeakPolarHBondContact O-CA 3.4Å; R115-G119 PolarHBondContact O-N 3.39Å; G119-V121 PolarHBondContact O-N 3.33Å; G119-G123 PolarHBondContact O-N 2.9Å; G119-G123 VanDerWaalsContact O-N 3.08Å
120	K	88.3	Confident	91.5	Very high	125 Å²	125	35.7 Å²	35.7	54%	0.543	21%	0.206	S	C	.	.	H	α-helix	trans	-62.6	-42.7	-168.9	-60.6	-177.9	-168.2	179.8	0	113.6	S16 R115 G123 V124	S16-K120 VanDerWaalsContact OG-CE 3.27Å; S16-K120 WeakPolarHBondContact OG-CE 3.25Å; S16-K120 PolarHBondContact OG-NZ 2.96Å; R115-K120 PolarHBondContact NH1-O 3.16Å; K120-G123 PolarHBondContact O-N 3.45Å; K120-V124 WeakPolarHBondContact O-CG2 3.47Å; K120-V124 PolarHBondContact O-N 3.05Å
121	V	91.1	Very high	91.7	Very high	111 Å²	111	36.3 Å²	36.3	67%	0.673	21%	0.212	S	C	*	.	H	α-helix	trans	-64.2	-51.5	-176.9	179	0	0	0	0	110.4	G119 G123 V124 L125	G119-V121 PolarHBondContact O-N 3.33Å; V121-G123 VanDerWaalsContact C-N 3.27Å; V121-G123 PolarHBondContact O-N 3.3Å; V121-V124 PolarHBondContact O-N 3.38Å; V121-V124 VanDerWaalsContact O-N 3.16Å; V121-L125 HydrophobicContact CG1-CD1 4.33Å; V121-L125 WeakPolarHBondContact O-CG 3.39Å; V121-L125 PolarHBondContact O-N 2.82Å
122	T	92.4	Very high	91.9	Very high	32 Å²	32	39.7 Å²	39.7	20%	0.196	23%	0.229	C	C	.	.	H	α-helix	trans	-59.8	-39.2	177.4	-43.7	0	0	0	0	111.6	V114 C118 L125 C126 F405 L408	V114-T122 HydrophobicContact CG1-CG2 3.76Å; C118-T122 HydrophobicContact CB-CG2 3.75Å; C118-T122 PolarHBondContact O-OG1 2.93Å; C118-T122 VanDerWaalsContact O-OG1 3.07Å; T122-L125 PolarHBondContact O-N 3.48Å; T122-C126 WeakPolarHBondContact O-CB 2.98Å; T122-C126 PolarHBondContact O-N 2.9Å; T122-F405 HydrophobicContact CG2-CD1 4.23Å; T122-F405 HydrophobicContact CG2-CE1 4.23Å; T122-L408 HydrophobicContact CG2-CD1 4.01Å
123	G	90.6	Very high	92.2	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-59.4	-45.8	174	0	0	0	0	0	113.4	G119 K120 V121 C126 E127	G119-G123 PolarHBondContact O-N 2.9Å; G119-G123 VanDerWaalsContact O-N 3.08Å; K120-G123 PolarHBondContact O-N 3.45Å; V121-G123 VanDerWaalsContact C-N 3.27Å; V121-G123 PolarHBondContact O-N 3.3Å; G123-C126 WeakPolarHBondContact O-CB 3.24Å; G123-C126 PolarHBondContact O-N 3.35Å; G123-E127 WeakPolarHBondContact O-CG 3.38Å; G123-E127 PolarHBondContact O-N 3.45Å
124	V	90.1	Very high	92.2	Very high	52 Å²	52	39.5 Å²	39.5	32%	0.315	23%	0.228	S	C	.	.	H	α-helix	trans	-67.1	-39.8	177.7	174.4	0	0	0	0	111.6	K120 V121 C126 E127 M128 L346	K120-V124 WeakPolarHBondContact O-CG2 3.47Å; K120-V124 PolarHBondContact O-N 3.05Å; V121-V124 PolarHBondContact O-N 3.38Å; V121-V124 VanDerWaalsContact O-N 3.16Å; V124-C126 VanDerWaalsContact C-N 3.3Å; V124-C126 PolarHBondContact O-N 3.23Å; V124-E127 WeakPolarHBondContact O-CB 3.47Å; V124-E127 PolarHBondContact O-N 3.48Å; V124-M128 WeakPolarHBondContact O-CG 3.24Å; V124-M128 PolarHBondContact O-N 3.41Å; V124-L346 HydrophobicContact CG1-CD2 4.18Å
125	L	93.9	Very high	92.2	Very high	101 Å²	101	42 Å²	42	53%	0.529	24%	0.239	S	C	.	.	H	α-helix	trans	-62.2	-40.5	174.7	-68.6	176.2	0	0	0	111.6	V121 T122 M128 A129	V121-L125 HydrophobicContact CG1-CD1 4.33Å; V121-L125 WeakPolarHBondContact O-CG 3.39Å; V121-L125 PolarHBondContact O-N 2.82Å; T122-L125 PolarHBondContact O-N 3.48Å; L125-M128 PolarHBondContact O-N 2.89Å; L125-A129 WeakPolarHBondContact O-CB 3.3Å; L125-A129 PolarHBondContact O-N 3.32Å
126	C	93.8	Very high	92.3	Very high	0 Å²	0	40.9 Å²	40.9	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-61.8	-43.1	174	-177.5	0	0	0	0	112	Y110 V114 T122 G123 V124 A129 I130 F405	Y110-C126 WeakPolarHBondContact CD1-SG 3.17Å; Y110-C126 WeakPolarHBondContact CE1-SG 3.34Å; V114-C126 HydrophobicContact CB-CB 4.34Å; V114-C126 HydrophobicContact CG1-CB 4.02Å; T122-C126 WeakPolarHBondContact O-CB 2.98Å; T122-C126 PolarHBondContact O-N 2.9Å; G123-C126 WeakPolarHBondContact O-CB 3.24Å; G123-C126 PolarHBondContact O-N 3.35Å; V124-C126 VanDerWaalsContact C-N 3.3Å; V124-C126 PolarHBondContact O-N 3.23Å; C126-A129 PolarHBondContact O-N 2.96Å; C126-I130 VanDerWaalsContact O-CG1 3.31Å; C126-I130 WeakPolarHBondContact O-CG1 3.17Å; C126-I130 PolarHBondContact O-N 2.89Å; C126-F405 VanDerWaalsContact CA-CZ 3.49Å; C126-F405 HydrophobicContact CB-CD1 4.17Å; C126-F405 HydrophobicContact CB-CE1 3.69Å; C126-F405 HydrophobicContact CB-CE2 4.32Å; C126-F405 HydrophobicContact CB-CZ 3.78Å
127	E	91.4	Very high	92.4	Very high	2 Å²	2	38.1 Å²	38.1	1%	0.009	21%	0.214	C	C	.	.	H	α-helix	trans	-59.2	-51.3	175.4	-76.7	167.9	-159.5	0	0	111.3	Q111 G123 V124 A129 I130 A131 V342 L346 R349	Q111-E127 HydrophobicContact CB-CG 3.54Å; Q111-E127 HydrophobicContact CG-CG 3.76Å; G123-E127 WeakPolarHBondContact O-CG 3.38Å; G123-E127 PolarHBondContact O-N 3.45Å; V124-E127 WeakPolarHBondContact O-CB 3.47Å; V124-E127 PolarHBondContact O-N 3.48Å; E127-A129 VanDerWaalsContact C-N 3.3Å; E127-A129 PolarHBondContact O-N 2.87Å; E127-I130 PolarHBondContact O-N 3.3Å; E127-A131 PolarHBondContact O-N 2.94Å; E127-V342 VanDerWaalsContact C-CG1 3.48Å; E127-V342 VanDerWaalsContact CA-CG1 3.42Å; E127-V342 HydrophobicContact CB-CG1 3.44Å; E127-V342 VanDerWaalsContact CB-CG1 3.44Å; E127-V342 HydrophobicContact CG-CG1 3.8Å; E127-V342 WeakPolarHBondContact O-CG1 3.41Å; E127-L346 HydrophobicContact CB-CD1 4.2Å; E127-L346 HydrophobicContact CB-CD2 3.93Å; E127-L346 HydrophobicContact CB-CG 4.06Å; E127-L346 VanDerWaalsContact OE2-CD2 3.29Å; E127-L346 WeakPolarHBondContact OE2-CD2 3.17Å; E127-R349 IonicContact OE1-CZ 3.53Å; E127-R349 IonicContact OE1-NH1 2.72Å; E127-R349 PolarHBondContact OE1-NH1 3.48Å; E127-R349 IonicContact OE1-NH2 3.9Å; E127-R349 PolarHBondContact OE1-NH2 2.93Å; E127-R349 IonicContact OE2-CZ 2.67Å; E127-R349 IonicContact OE2-NH1 2.63Å; E127-R349 PolarHBondContact OE2-NH1 2.89Å
128	M	92.9	Very high	92.5	Very high	99 Å²	99	36.6 Å²	36.6	49%	0.488	21%	0.205	S	C	.	.	H	α-helix	trans	-58.7	-42.9	177.2	-68.4	-174.9	70.3	0	0	112	V124 L125 A131 I132 L346	V124-M128 WeakPolarHBondContact O-CG 3.24Å; V124-M128 PolarHBondContact O-N 3.41Å; L125-M128 PolarHBondContact O-N 2.89Å; M128-A131 PolarHBondContact O-N 3.35Å; M128-I132 VanDerWaalsContact O-CG1 3.31Å; M128-I132 WeakPolarHBondContact O-CG1 3.44Å; M128-I132 PolarHBondContact O-N 3Å; M128-L346 HydrophobicContact CG-CD1 4.36Å
129	A	94.6	Very high	92.5	Very high	13 Å²	13	36 Å²	36	11%	0.107	20%	0.2	C	C	.	.	H	α-helix	trans	-61.7	-46.8	177.3	0	0	0	0	0	111.8	L125 C126 E127 A131 I132 Y133 L397 F401 F405	L125-A129 WeakPolarHBondContact O-CB 3.3Å; L125-A129 PolarHBondContact O-N 3.32Å; C126-A129 PolarHBondContact O-N 2.96Å; E127-A129 VanDerWaalsContact C-N 3.3Å; E127-A129 PolarHBondContact O-N 2.87Å; A129-A131 VanDerWaalsContact C-N 3.31Å; A129-A131 PolarHBondContact O-N 2.87Å; A129-I132 PolarHBondContact O-N 2.99Å; A129-Y133 VanDerWaalsContact O-CB 3.28Å; A129-Y133 WeakPolarHBondContact O-CB 3.33Å; A129-Y133 PolarHBondContact O-N 3.49Å; A129-L397 HydrophobicContact CB-CD2 4.45Å; A129-F401 VanDerWaalsContact C-CZ 3.49Å; A129-F401 HydrophobicContact CB-CE1 3.73Å; A129-F401 HydrophobicContact CB-CZ 3.74Å; A129-F405 HydrophobicContact CB-CE2 4.31Å; A129-F405 HydrophobicContact CB-CZ 4.4Å
130	I	92.8	Very high	92.6	Very high	1 Å²	1	34.5 Å²	34.5	1%	0.005	18%	0.184	C	C	.	.	H	α-helix	trans	-62	-41.2	178.6	-68.9	169.2	0	0	0	110.4	Y110 Q111 C126 E127 Y133 T134 V255 V342 F401	Y110-I130 HydrophobicContact CD1-CD1 3.74Å; Y110-I130 HydrophobicContact CE1-CD1 4.49Å; Y110-I130 HydrophobicContact CG-CD1 4.2Å; Q111-I130 HydrophobicContact CB-CD1 4.29Å; C126-I130 VanDerWaalsContact O-CG1 3.31Å; C126-I130 WeakPolarHBondContact O-CG1 3.17Å; C126-I130 PolarHBondContact O-N 2.89Å; E127-I130 PolarHBondContact O-N 3.3Å; I130-Y133 PolarHBondContact O-N 3.27Å; I130-T134 HydrophobicContact CG2-CG2 4.07Å; I130-T134 WeakPolarHBondContact O-CB 3.45Å; I130-T134 WeakPolarHBondContact O-CG2 3.41Å; I130-T134 PolarHBondContact O-N 3.26Å; I130-T134 PolarHBondContact O-OG1 3.18Å; I130-V255 HydrophobicContact CD1-CG1 4.5Å; I130-V255 HydrophobicContact CG1-CG1 4.38Å; I130-V255 HydrophobicContact CG1-CG2 4.36Å; I130-V255 HydrophobicContact CG2-CG1 3.84Å; I130-V342 HydrophobicContact CB-CG2 4.22Å; I130-V342 HydrophobicContact CG2-CG2 3.8Å; I130-F401 HydrophobicContact CG1-CD1 4.27Å; I130-F401 HydrophobicContact CG1-CE1 3.57Å; I130-F401 HydrophobicContact CG1-CZ 3.94Å
131	A	92.8	Very high	92.8	Very high	14 Å²	14	29 Å²	29	12%	0.116	16%	0.16	C	C	.	.	H	α-helix	trans	-60.6	-49	177.2	0	0	0	0	0	111.4	E127 M128 A129 Y133 T134 F135 V342 V343 W373	E127-A131 PolarHBondContact O-N 2.94Å; M128-A131 PolarHBondContact O-N 3.35Å; A129-A131 VanDerWaalsContact C-N 3.31Å; A129-A131 PolarHBondContact O-N 2.87Å; A131-Y133 PolarHBondContact O-N 3.29Å; A131-T134 PolarHBondContact O-OG1 3.43Å; A131-F135 WeakPolarHBondContact O-CB 3.32Å; A131-F135 PolarHBondContact O-N 3Å; A131-V342 HydrophobicContact CB-CG1 4.39Å; A131-V343 HydrophobicContact CB-CG2 4.43Å; A131-W373 VanDerWaalsContact O-CH2 3.29Å; A131-W373 WeakPolarHBondContact O-CH2 3.44Å
132	I	94.1	Very high	93	Very high	89 Å²	89	23.7 Å²	23.7	46%	0.456	13%	0.128	S	C	.	.	H	α-helix	trans	-64.4	-43.7	179	-62.3	164.6	0	0	0	111	M128 A129 F135 G136 L397	M128-I132 VanDerWaalsContact O-CG1 3.31Å; M128-I132 WeakPolarHBondContact O-CG1 3.44Å; M128-I132 PolarHBondContact O-N 3Å; A129-I132 PolarHBondContact O-N 2.99Å; I132-F135 PolarHBondContact O-N 2.66Å; I132-G136 PolarHBondContact O-N 3.42Å; I132-L397 HydrophobicContact CB-CD1 3.99Å; I132-L397 HydrophobicContact CG2-CD1 3.53Å
133	Y	94	Very high	93	Very high	12 Å²	12	22.2 Å²	22.2	5%	0.047	12%	0.119	C	C	.	.	H	α-helix	trans	-62.5	-49.7	179.7	174.3	-96.8	0	0	0	112.8	A129 I130 A131 F135 G136 T137 F249 Q252 V255 I394 L397 A398 F401	A129-Y133 VanDerWaalsContact O-CB 3.28Å; A129-Y133 WeakPolarHBondContact O-CB 3.33Å; A129-Y133 PolarHBondContact O-N 3.49Å; I130-Y133 PolarHBondContact O-N 3.27Å; A131-Y133 PolarHBondContact O-N 3.29Å; Y133-F135 VanDerWaalsContact C-N 3.29Å; Y133-F135 PolarHBondContact O-N 2.73Å; Y133-G136 PolarHBondContact O-N 2.94Å; Y133-T137 WeakPolarHBondContact O-CB 3.33Å; Y133-T137 PolarHBondContact O-N 2.87Å; Y133-T137 PolarHBondContact O-OG1 3.44Å; Y133-F249 HydrophobicContact CE2-CD2 4.29Å; Y133-Q252 HydrophobicContact CE1-CG 3.94Å; Y133-Q252 HydrophobicContact CE2-CG 4.19Å; Y133-Q252 VanDerWaalsContact OH-CB 3.31Å; Y133-Q252 WeakPolarHBondContact OH-CB 3.12Å; Y133-Q252 WeakPolarHBondContact OH-CG 3.29Å; Y133-V255 HydrophobicContact CD1-CG2 4.36Å; Y133-I394 HydrophobicContact CD2-CB 3.93Å; Y133-I394 WeakPolarHBondContact CD2-O 3.3Å; Y133-I394 HydrophobicContact CE2-CB 4.13Å; Y133-I394 HydrophobicContact CE2-CG1 4.47Å; Y133-L397 HydrophobicContact CD2-CB 4.26Å; Y133-A398 HydrophobicContact CE2-CB 3.98Å; Y133-F401 HydrophobicContact CD1-CE2 4.01Å; Y133-F401 AromaticContact CD2-CE2 3.91Å; Y133-F401 HydrophobicContact CD2-CE2 3.91Å; Y133-F401 HydrophobicContact CG-CD2 4.36Å; Y133-F401 AromaticContact CG-CE2 3.53Å; Y133-F401 HydrophobicContact CG-CE2 3.53Å; Y133-F401 HydrophobicContact CG-CZ 4.35Å
134	T	92.3	Very high	93.1	Very high	1 Å²	1	22.2 Å²	22.2	1%	0.006	12%	0.119	C	C	.	.	H	α-helix	trans	-65.1	-36.3	179.5	51	0	0	0	0	111.1	I130 A131 T137 C138 C338 G339 W373	I130-T134 HydrophobicContact CG2-CG2 4.07Å; I130-T134 WeakPolarHBondContact O-CB 3.45Å; I130-T134 WeakPolarHBondContact O-CG2 3.41Å; I130-T134 PolarHBondContact O-N 3.26Å; I130-T134 PolarHBondContact O-OG1 3.18Å; A131-T134 PolarHBondContact O-OG1 3.43Å; T134-T137 PolarHBondContact O-N 2.89Å; T134-C138 PolarHBondContact O-N 3.41Å; T134-C138 PolarHBondContact O-SG 2.95Å; T134-C338 HydrophobicContact CG2-CB 4.3Å; T134-G339 WeakPolarHBondContact OG1-CA 3.38Å; T134-W373 WeakPolarHBondContact OG1-CZ2 3.29Å
135	F	93.4	Very high	93.2	Very high	51 Å²	51	19.8 Å²	19.8	22%	0.224	10%	0.104	C	C	.	.	H	α-helix	trans	-63	-50.7	175.7	-177	-94.3	0	0	0	111.6	A131 I132 Y133 T137 C138 I139 W373 V376 T377 L380	A131-F135 WeakPolarHBondContact O-CB 3.32Å; A131-F135 PolarHBondContact O-N 3Å; I132-F135 PolarHBondContact O-N 2.66Å; Y133-F135 VanDerWaalsContact C-N 3.29Å; Y133-F135 PolarHBondContact O-N 2.73Å; F135-T137 VanDerWaalsContact C-N 3.33Å; F135-T137 PolarHBondContact O-N 2.89Å; F135-C138 WeakPolarHBondContact O-CB 3.41Å; F135-C138 PolarHBondContact O-N 3Å; F135-I139 HydrophobicContact CD1-CD1 3.93Å; F135-I139 HydrophobicContact CE1-CD1 3.61Å; F135-I139 HydrophobicContact CZ-CD1 4.34Å; F135-I139 PolarHBondContact O-N 3.38Å; F135-W373 VanDerWaalsContact CA-CZ2 3.42Å; F135-W373 HydrophobicContact CB-CH2 3.79Å; F135-W373 HydrophobicContact CB-CZ2 3.57Å; F135-W373 AromaticContact CD2-CD2 4Å; F135-W373 HydrophobicContact CD2-CD2 4Å; F135-W373 AromaticContact CD2-CE2 3.83Å; F135-W373 HydrophobicContact CD2-CE3 4.26Å; F135-W373 HydrophobicContact CD2-CH2 4.35Å; F135-W373 HydrophobicContact CD2-CZ2 4.08Å; F135-W373 HydrophobicContact CD2-CZ3 4.39Å; F135-W373 HydrophobicContact CG-CZ2 4.34Å; F135-V376 HydrophobicContact CE2-CB 4.39Å; F135-V376 HydrophobicContact CE2-CG1 4.1Å; F135-V376 HydrophobicContact CZ-CB 4.46Å; F135-V376 HydrophobicContact CZ-CG1 3.73Å; F135-T377 HydrophobicContact CD2-CG2 3.46Å; F135-T377 VanDerWaalsContact CD2-CG2 3.46Å; F135-T377 HydrophobicContact CE1-CG2 4.45Å; F135-T377 HydrophobicContact CE2-CG2 3.37Å; F135-T377 HydrophobicContact CG-CG2 4.07Å; F135-T377 HydrophobicContact CZ-CG2 3.91Å; F135-L380 HydrophobicContact CE1-CD1 3.67Å; F135-L380 HydrophobicContact CZ-CD1 3.64Å
136	G	93.8	Very high	93.1	Very high	8 Å²	8	15 Å²	15	8%	0.082	8%	0.079	C	C	.	.	H	α-helix	trans	-64.2	-36.2	176.9	0	0	0	0	0	113	I132 Y133 C138 I139 A140 V390	I132-G136 PolarHBondContact O-N 3.42Å; Y133-G136 PolarHBondContact O-N 2.94Å; G136-C138 PolarHBondContact O-N 3.48Å; G136-I139 WeakPolarHBondContact O-CB 3.49Å; G136-I139 PolarHBondContact O-N 3Å; G136-A140 PolarHBondContact O-N 3.36Å; G136-V390 WeakPolarHBondContact O-CG1 3.38Å
137	T	92.7	Very high	92.9	Very high	3 Å²	3	16 Å²	16	2%	0.018	8%	0.084	C	C	.	.	H	α-helix	trans	-67.6	-36.3	176.1	-48.5	0	0	0	0	112	Y133 T134 F135 I139 A140 F141 F249 L335	Y133-T137 WeakPolarHBondContact O-CB 3.33Å; Y133-T137 PolarHBondContact O-N 2.87Å; Y133-T137 PolarHBondContact O-OG1 3.44Å; T134-T137 PolarHBondContact O-N 2.89Å; F135-T137 VanDerWaalsContact C-N 3.33Å; F135-T137 PolarHBondContact O-N 2.89Å; T137-I139 VanDerWaalsContact C-N 3.29Å; T137-I139 PolarHBondContact O-N 3.48Å; T137-A140 PolarHBondContact O-N 3.09Å; T137-F141 HydrophobicContact CG2-CD1 4.11Å; T137-F141 HydrophobicContact CG2-CE1 3.7Å; T137-F141 HydrophobicContact CG2-CE2 4.32Å; T137-F141 HydrophobicContact CG2-CZ 3.82Å; T137-F141 WeakPolarHBondContact O-CB 3.26Å; T137-F141 WeakPolarHBondContact O-CD1 3.29Å; T137-F141 WeakPolarHBondContact O-CG 3.26Å; T137-F141 PolarHBondContact O-N 3.2Å; T137-F249 HydrophobicContact CG2-CE2 3.88Å; T137-F249 HydrophobicContact CG2-CZ 4.23Å; T137-L335 VanDerWaalsContact CB-CD2 3.42Å; T137-L335 HydrophobicContact CG2-CD2 3.23Å
138	C	93	Very high	93	Very high	0 Å²	0	15.9 Å²	15.9	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-60.3	-38.6	171.5	-75.1	0	0	0	0	112.1	T134 F135 G136 F141 F142 Y332 T377	T134-C138 PolarHBondContact O-N 3.41Å; T134-C138 PolarHBondContact O-SG 2.95Å; F135-C138 WeakPolarHBondContact O-CB 3.41Å; F135-C138 PolarHBondContact O-N 3Å; G136-C138 PolarHBondContact O-N 3.48Å; C138-F141 PolarHBondContact O-N 3.24Å; C138-F142 WeakPolarHBondContact O-CD2 3.45Å; C138-F142 PolarHBondContact O-N 3.05Å; C138-Y332 HydrophobicContact CB-CD2 4.27Å; C138-Y332 HydrophobicContact CB-CE2 3.5Å; C138-T377 HydrophobicContact CB-CG2 3.92Å
139	I	94	Very high	92.9	Very high	10 Å²	10	12.2 Å²	12.2	5%	0.051	7%	0.066	C	C	.	.	H	α-helix	trans	-63.8	-49.7	174	-63.6	170.1	0	0	0	110.2	F135 G136 T137 F141 F142 I143 T377 L380 A381 I384 V390	F135-I139 HydrophobicContact CD1-CD1 3.93Å; F135-I139 HydrophobicContact CE1-CD1 3.61Å; F135-I139 HydrophobicContact CZ-CD1 4.34Å; F135-I139 PolarHBondContact O-N 3.38Å; G136-I139 WeakPolarHBondContact O-CB 3.49Å; G136-I139 PolarHBondContact O-N 3Å; T137-I139 VanDerWaalsContact C-N 3.29Å; T137-I139 PolarHBondContact O-N 3.48Å; I139-F141 PolarHBondContact O-N 2.88Å; I139-F142 PolarHBondContact O-N 2.95Å; I139-F142 VanDerWaalsContact O-N 3.12Å; I139-I143 HydrophobicContact CG2-CD1 3.99Å; I139-I143 WeakPolarHBondContact O-CG1 3.38Å; I139-I143 PolarHBondContact O-N 3.05Å; I139-I143 VanDerWaalsContact O-N 3.08Å; I139-T377 HydrophobicContact CG1-CG2 4.04Å; I139-L380 HydrophobicContact CD1-CB 3.95Å; I139-L380 HydrophobicContact CD1-CD1 3.72Å; I139-L380 HydrophobicContact CG1-CB 4.33Å; I139-A381 HydrophobicContact CG2-CB 4.12Å; I139-I384 HydrophobicContact CG2-CD1 3.91Å; I139-V390 HydrophobicContact CG2-CG2 4.31Å
140	A	93.1	Very high	92.7	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-56.3	-40.4	177.9	0	0	0	0	0	111.8	G136 T137 F142 I143 V144 I387 V390	G136-A140 PolarHBondContact O-N 3.36Å; T137-A140 PolarHBondContact O-N 3.09Å; A140-F142 PolarHBondContact O-N 3.28Å; A140-I143 PolarHBondContact O-N 3.25Å; A140-V144 VanDerWaalsContact O-CG2 3.31Å; A140-V144 WeakPolarHBondContact O-CG2 3.24Å; A140-V144 PolarHBondContact O-N 3Å; A140-I387 HydrophobicContact CB-CG1 4.22Å; A140-V390 HydrophobicContact CB-CG1 4.07Å
141	F	92.9	Very high	92.5	Very high	9 Å²	9	18.1 Å²	18.1	4%	0.039	9%	0.09	C	C	.	.	H	α-helix	trans	-62.3	-41.4	176.7	-76.3	0.3	0	0	0	113.4	A62 T137 C138 I139 V144 I145 V328 Y332 L335	A62-F141 HydrophobicContact CB-CD1 4.13Å; A62-F141 HydrophobicContact CB-CE1 3.99Å; T137-F141 HydrophobicContact CG2-CD1 4.11Å; T137-F141 HydrophobicContact CG2-CE1 3.7Å; T137-F141 HydrophobicContact CG2-CE2 4.32Å; T137-F141 HydrophobicContact CG2-CZ 3.82Å; T137-F141 WeakPolarHBondContact O-CB 3.26Å; T137-F141 WeakPolarHBondContact O-CD1 3.29Å; T137-F141 WeakPolarHBondContact O-CG 3.26Å; T137-F141 PolarHBondContact O-N 3.2Å; C138-F141 PolarHBondContact O-N 3.24Å; I139-F141 PolarHBondContact O-N 2.88Å; F141-V144 PolarHBondContact O-N 3.41Å; F141-I145 WeakPolarHBondContact O-CB 3.09Å; F141-I145 VanDerWaalsContact O-CG1 3.25Å; F141-I145 WeakPolarHBondContact O-CG1 3.2Å; F141-I145 PolarHBondContact O-N 3.39Å; F141-V328 HydrophobicContact CB-CG1 3.38Å; F141-V328 HydrophobicContact CD1-CG1 3.7Å; F141-V328 HydrophobicContact CD2-CG1 3.94Å; F141-V328 HydrophobicContact CE1-CG1 4.42Å; F141-V328 HydrophobicContact CG-CG1 3.41Å; F141-V328 VanDerWaalsContact CG-CG1 3.41Å; F141-Y332 HydrophobicContact CB-CD2 3.99Å; F141-Y332 AromaticContact CD2-CD2 3.99Å; F141-Y332 HydrophobicContact CD2-CD2 3.99Å; F141-Y332 HydrophobicContact CD2-CG 4.36Å; F141-L335 HydrophobicContact CE2-CD1 4.08Å; F141-L335 HydrophobicContact CE2-CD2 4.33Å; F141-L335 HydrophobicContact CZ-CD1 4.27Å; F141-L335 HydrophobicContact CZ-CD2 4.37Å
142	F	93.6	Very high	92.4	Very high	1 Å²	1	19.5 Å²	19.5	0%	0.004	10%	0.095	C	C	.	.	H	α-helix	trans	-65.7	-38.5	174.4	-76.9	-50.1	0	0	0	112.6	C138 I139 A140 I145 G146 I176 A180 I184 Y332 F374 L378 A381	C138-F142 WeakPolarHBondContact O-CD2 3.45Å; C138-F142 PolarHBondContact O-N 3.05Å; I139-F142 PolarHBondContact O-N 2.95Å; I139-F142 VanDerWaalsContact O-N 3.12Å; A140-F142 PolarHBondContact O-N 3.28Å; F142-I145 PolarHBondContact O-N 3.48Å; F142-G146 PolarHBondContact O-N 3.49Å; F142-I176 HydrophobicContact CB-CG2 4.38Å; F142-I176 HydrophobicContact CD1-CG2 4.26Å; F142-A180 HydrophobicContact CD1-CB 4.16Å; F142-A180 HydrophobicContact CE1-CB 3.39Å; F142-A180 HydrophobicContact CZ-CB 4.03Å; F142-I184 HydrophobicContact CD1-CD1 4.11Å; F142-I184 HydrophobicContact CE1-CD1 3.6Å; F142-Y332 HydrophobicContact CD2-CE2 4.12Å; F142-Y332 HydrophobicContact CE1-CE2 4.26Å; F142-Y332 AromaticContact CE2-CE2 3.61Å; F142-Y332 HydrophobicContact CE2-CE2 3.61Å; F142-Y332 AromaticContact CE2-CZ 3.84Å; F142-Y332 WeakPolarHBondContact CE2-OH 3.47Å; F142-Y332 AromaticContact CZ-CE2 3.68Å; F142-Y332 HydrophobicContact CZ-CE2 3.68Å; F142-Y332 AromaticContact CZ-CZ 3.78Å; F142-F374 HydrophobicContact CE1-CE2 4.31Å; F142-F374 HydrophobicContact CZ-CD2 4Å; F142-F374 AromaticContact CZ-CE2 3.65Å; F142-F374 HydrophobicContact CZ-CE2 3.65Å; F142-F374 HydrophobicContact CZ-CZ 4.24Å; F142-L378 HydrophobicContact CD1-CD1 4.35Å; F142-L378 HydrophobicContact CD2-CB 4.41Å; F142-L378 HydrophobicContact CE1-CD1 4.36Å; F142-L378 HydrophobicContact CE2-CB 3.97Å; F142-L378 HydrophobicContact CG-CD1 4.45Å; F142-L378 HydrophobicContact CZ-CB 4.33Å; F142-L378 HydrophobicContact CZ-CD1 4.44Å; F142-A381 HydrophobicContact CB-CB 3.41Å; F142-A381 VanDerWaalsContact CB-CB 3.41Å; F142-A381 HydrophobicContact CD2-CB 4.23Å; F142-A381 HydrophobicContact CG-CB 4.23Å
143	I	92.6	Very high	92	Very high	0 Å²	0	17.6 Å²	17.6	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-61	-50.6	175.8	-65.5	169.1	0	0	0	110	I139 A140 I145 G146 D147 A381 I384 I387 V390	I139-I143 HydrophobicContact CG2-CD1 3.99Å; I139-I143 WeakPolarHBondContact O-CG1 3.38Å; I139-I143 PolarHBondContact O-N 3.05Å; I139-I143 VanDerWaalsContact O-N 3.08Å; A140-I143 PolarHBondContact O-N 3.25Å; I143-I145 PolarHBondContact O-N 3.31Å; I143-G146 PolarHBondContact O-N 2.81Å; I143-G146 VanDerWaalsContact O-N 3.14Å; I143-D147 VanDerWaalsContact O-CG 3.23Å; I143-D147 PolarHBondContact O-N 2.93Å; I143-A381 HydrophobicContact CG1-CB 4.22Å; I143-I384 HydrophobicContact CD1-CB 4.1Å; I143-I384 HydrophobicContact CD1-CG2 3.75Å; I143-I387 HydrophobicContact CG2-CB 3.92Å; I143-I387 HydrophobicContact CG2-CG1 4.41Å; I143-V390 HydrophobicContact CD1-CG2 4.06Å
144	V	92.7	Very high	91.6	Very high	0 Å²	0	18.4 Å²	18.4	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-58.5	-47.4	177.7	175.8	0	0	0	0	111.2	A62 L65 A140 F141 G146 D147 Q148 I324 V328 I387	A62-V144 HydrophobicContact CB-CG1 4.49Å; A62-V144 HydrophobicContact CB-CG2 3.93Å; L65-V144 HydrophobicContact CD1-CG1 4.17Å; A140-V144 VanDerWaalsContact O-CG2 3.31Å; A140-V144 WeakPolarHBondContact O-CG2 3.24Å; A140-V144 PolarHBondContact O-N 3Å; F141-V144 PolarHBondContact O-N 3.41Å; V144-G146 VanDerWaalsContact C-N 3.27Å; V144-G146 PolarHBondContact O-N 3.46Å; V144-D147 PolarHBondContact O-N 3.49Å; V144-Q148 HydrophobicContact CG1-CG 3.97Å; V144-Q148 WeakPolarHBondContact O-CB 3.13Å; V144-Q148 WeakPolarHBondContact O-CG 3.38Å; V144-Q148 PolarHBondContact O-N 2.9Å; V144-I324 HydrophobicContact CG1-CG2 3.73Å; V144-V328 HydrophobicContact CG1-CG2 4.04Å; V144-I387 HydrophobicContact CG2-CD1 3.26Å
145	I	92.3	Very high	91.1	Very high	1 Å²	1	19 Å²	19	1%	0.005	10%	0.1	C	C	.	.	H	α-helix	trans	-59	-43.1	178.6	-72.2	168.4	0	0	0	110.8	F141 F142 I143 L149 T179 I184 V328 V329	F141-I145 WeakPolarHBondContact O-CB 3.09Å; F141-I145 VanDerWaalsContact O-CG1 3.25Å; F141-I145 WeakPolarHBondContact O-CG1 3.2Å; F141-I145 PolarHBondContact O-N 3.39Å; F142-I145 PolarHBondContact O-N 3.48Å; I143-I145 PolarHBondContact O-N 3.31Å; I145-L149 HydrophobicContact CG2-CD1 3.56Å; I145-L149 HydrophobicContact CG2-CG 4.25Å; I145-L149 VanDerWaalsContact O-CB 3.23Å; I145-L149 WeakPolarHBondContact O-CB 3.33Å; I145-L149 WeakPolarHBondContact O-CG 3.27Å; I145-L149 PolarHBondContact O-N 3.42Å; I145-T179 HydrophobicContact CG2-CG2 4.04Å; I145-I184 HydrophobicContact CD1-CD1 3.48Å; I145-I184 VanDerWaalsContact CD1-CD1 3.48Å; I145-V328 HydrophobicContact CD1-CB 4.38Å; I145-V328 HydrophobicContact CD1-CG1 3.81Å; I145-V328 HydrophobicContact CG1-CB 4.17Å; I145-V328 HydrophobicContact CG1-CG1 3.84Å; I145-V329 HydrophobicContact CD1-CG2 3.69Å; I145-V329 HydrophobicContact CG1-CG2 4.38Å
146	G	91.4	Very high	90.5	Very high	0 Å²	0	20.8 Å²	20.8	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-60.3	-50	176.8	0	0	0	0	0	113	F142 I143 V144 L149 D150	F142-G146 PolarHBondContact O-N 3.49Å; I143-G146 PolarHBondContact O-N 2.81Å; I143-G146 VanDerWaalsContact O-N 3.14Å; V144-G146 VanDerWaalsContact C-N 3.27Å; V144-G146 PolarHBondContact O-N 3.46Å; G146-L149 PolarHBondContact O-N 2.86Å; G146-D150 VanDerWaalsContact O-CB 3.24Å; G146-D150 WeakPolarHBondContact O-CB 3.34Å; G146-D150 PolarHBondContact O-N 3.47Å
147	D	91.1	Very high	89.6	Confident	21 Å²	21	22.8 Å²	22.8	11%	0.112	13%	0.13	C	C	.	.	H	α-helix	trans	-64.6	-43.2	-177.4	-64.6	-10.9	0	0	0	111.4	I143 V144 R151 R172 M308	I143-D147 VanDerWaalsContact O-CG 3.23Å; I143-D147 PolarHBondContact O-N 2.93Å; V144-D147 PolarHBondContact O-N 3.49Å; D147-R151 WeakPolarHBondContact O-CG 3.33Å; D147-R151 PolarHBondContact O-N 2.97Å; D147-R172 IonicContact OD1-CZ 3Å; D147-R172 IonicContact OD1-NE 3.05Å; D147-R172 PolarHBondContact OD1-NE 2.84Å; D147-R172 IonicContact OD1-NH2 2.66Å; D147-R172 PolarHBondContact OD1-NH2 2.78Å; D147-M308 HydrophobicContact CB-CE 3.98Å; D147-M308 HydrophobicContact CB-SD 3.95Å
148	Q	93.4	Very high	88.3	Confident	0 Å²	0	29.4 Å²	29.4	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-71.1	-38.8	-179.9	-61.9	-54	-36.8	0	0	112.4	V144 L152 D305 R321 I324 V325	V144-Q148 HydrophobicContact CG1-CG 3.97Å; V144-Q148 WeakPolarHBondContact O-CB 3.13Å; V144-Q148 WeakPolarHBondContact O-CG 3.38Å; V144-Q148 PolarHBondContact O-N 2.9Å; Q148-L152 VanDerWaalsContact O-CB 3.3Å; Q148-L152 WeakPolarHBondContact O-CB 3.39Å; Q148-L152 PolarHBondContact O-N 2.82Å; Q148-D305 VanDerWaalsContact NE2-CG 3.27Å; Q148-D305 PolarHBondContact NE2-OD1 3.3Å; Q148-D305 PolarHBondContact NE2-OD2 2.91Å; Q148-R321 HydrophobicContact CB-CB 4.28Å; Q148-R321 VanDerWaalsContact OE1-CB 3.27Å; Q148-R321 VanDerWaalsContact OE1-CD 3.26Å; Q148-I324 HydrophobicContact CG-CG2 3.95Å; Q148-V325 HydrophobicContact CB-CG2 3.61Å
149	L	91.5	Very high	86.5	Confident	23 Å²	23	37.1 Å²	37.1	12%	0.12	20%	0.197	C	C	.	.	H	α-helix	trans	-70.8	-39.6	176.9	-73.1	175.9	0	0	0	112.4	I145 G146 R151 L152 I153 T175 T179 V325	I145-L149 HydrophobicContact CG2-CD1 3.56Å; I145-L149 HydrophobicContact CG2-CG 4.25Å; I145-L149 VanDerWaalsContact O-CB 3.23Å; I145-L149 WeakPolarHBondContact O-CB 3.33Å; I145-L149 WeakPolarHBondContact O-CG 3.27Å; I145-L149 PolarHBondContact O-N 3.42Å; G146-L149 PolarHBondContact O-N 2.86Å; L149-R151 VanDerWaalsContact C-N 3.33Å; L149-R151 PolarHBondContact O-N 3.01Å; L149-L152 HydrophobicContact CD2-CD2 4.37Å; L149-L152 PolarHBondContact O-N 3.1Å; L149-I153 WeakPolarHBondContact O-CB 3.15Å; L149-I153 VanDerWaalsContact O-CG1 3.27Å; L149-I153 WeakPolarHBondContact O-CG1 3.38Å; L149-I153 PolarHBondContact O-N 2.63Å; L149-T175 HydrophobicContact CB-CG2 3.73Å; L149-T175 HydrophobicContact CD1-CG2 3.63Å; L149-T175 HydrophobicContact CG-CG2 4.24Å; L149-T179 HydrophobicContact CD1-CG2 4.2Å; L149-T179 VanDerWaalsContact CD1-OG1 3.3Å; L149-T179 WeakPolarHBondContact CD1-OG1 3.46Å; L149-V325 HydrophobicContact CD2-CG1 4.23Å; L149-V325 HydrophobicContact CD2-CG2 4.11Å; L149-V325 HydrophobicContact CG-CG1 4.41Å; L149-V325 HydrophobicContact CG-CG2 4.06Å
150	D	89.7	Confident	84.8	Confident	57 Å²	57	41.4 Å²	41.4	31%	0.305	22%	0.223	S	C	.	.	H	α-helix	trans	-56.5	-48.5	175.6	-177.8	70.4	0	0	0	110.8	G146 L152 I153 A154 R172	G146-D150 VanDerWaalsContact O-CB 3.24Å; G146-D150 WeakPolarHBondContact O-CB 3.34Å; G146-D150 PolarHBondContact O-N 3.47Å; D150-L152 PolarHBondContact O-N 2.67Å; D150-I153 PolarHBondContact O-N 2.84Å; D150-A154 WeakPolarHBondContact O-CB 3.4Å; D150-A154 PolarHBondContact O-N 3.3Å; D150-R172 HydrophobicContact CB-CB 4.43Å; D150-R172 HydrophobicContact CB-CG 4.46Å
151	R	88.9	Confident	82.6	Confident	81 Å²	81	47.8 Å²	47.8	31%	0.306	26%	0.257	S	S	.	.	H	α-helix	trans	-67	-35.1	175.9	-65.5	-59.5	-169.7	175.9	1.5	113.6	D147 L149 A154 A155 M308	D147-R151 WeakPolarHBondContact O-CG 3.33Å; D147-R151 PolarHBondContact O-N 2.97Å; L149-R151 VanDerWaalsContact C-N 3.33Å; L149-R151 PolarHBondContact O-N 3.01Å; R151-A154 PolarHBondContact O-N 3.4Å; R151-A155 PolarHBondContact O-N 3.2Å; R151-M308 HydrophobicContact CG-CE 4Å; R151-M308 HydrophobicContact CG-SD 3.54Å; R151-M308 VanDerWaalsContact CG-SD 3.54Å
152	L	89.3	Confident	80.6	Confident	43 Å²	43	51.6 Å²	51.6	23%	0.225	30%	0.299	C	S	.	.	H	α-helix	trans	-68.3	-40.4	177.5	-173.9	64.2	0	0	0	111.5	Q148 L149 D150 A155 V156 A318 A322	Q148-L152 VanDerWaalsContact O-CB 3.3Å; Q148-L152 WeakPolarHBondContact O-CB 3.39Å; Q148-L152 PolarHBondContact O-N 2.82Å; L149-L152 HydrophobicContact CD2-CD2 4.37Å; L149-L152 PolarHBondContact O-N 3.1Å; D150-L152 PolarHBondContact O-N 2.67Å; L152-A155 WeakPolarHBondContact O-CB 2.83Å; L152-A155 PolarHBondContact O-N 3.09Å; L152-V156 WeakPolarHBondContact O-CG2 3.29Å; L152-V156 PolarHBondContact O-N 3.4Å; L152-A318 HydrophobicContact CD1-CB 3.94Å; L152-A322 HydrophobicContact CD2-CB 4.25Å
153	I	87.4	Confident	78.5	Confident	48 Å²	48	55.1 Å²	55.1	25%	0.246	32%	0.324	C	S	.	.	H	α-helix	trans	-64.7	-43.7	174.5	-68.9	166.5	0	0	0	109.9	L149 D150 A155 V156 A157 T170 T175	L149-I153 WeakPolarHBondContact O-CB 3.15Å; L149-I153 VanDerWaalsContact O-CG1 3.27Å; L149-I153 WeakPolarHBondContact O-CG1 3.38Å; L149-I153 PolarHBondContact O-N 2.63Å; D150-I153 PolarHBondContact O-N 2.84Å; I153-A155 VanDerWaalsContact C-N 3.3Å; I153-A155 PolarHBondContact O-N 3.47Å; I153-V156 PolarHBondContact O-N 3.01Å; I153-A157 VanDerWaalsContact O-CB 3.27Å; I153-A157 WeakPolarHBondContact O-CB 3.24Å; I153-A157 PolarHBondContact O-N 3.33Å; I153-T170 HydrophobicContact CG2-CG2 3.58Å; I153-T175 HydrophobicContact CD1-CG2 3.82Å
154	A	83.7	Confident	76.5	Confident	30 Å²	30	61.5 Å²	61.5	25%	0.248	37%	0.365	C	S	.	.	H	α-helix	trans	-58.6	-40.9	175.8	0	0	0	0	0	112.2	D150 R151 V156 A157 H158 P312	D150-A154 WeakPolarHBondContact O-CB 3.4Å; D150-A154 PolarHBondContact O-N 3.3Å; R151-A154 PolarHBondContact O-N 3.4Å; A154-V156 PolarHBondContact O-N 3.03Å; A154-A157 PolarHBondContact O-N 3.15Å; A154-H158 WeakPolarHBondContact O-CB 3.19Å; A154-H158 PolarHBondContact O-CD2 3.03Å; A154-H158 VanDerWaalsContact O-CD2 3.32Å; A154-H158 PolarHBondContact O-N 3.3Å; A154-P312 HydrophobicContact CB-CB 4.26Å
155	A	82.8	Confident	74.6	Confident	13 Å²	13	69.3 Å²	69.3	11%	0.107	40%	0.402	C	S	.	.	H	α-helix	trans	-59.3	-46.3	176.6	0	0	0	0	0	112.3	R151 L152 I153 P312 A318	R151-A155 PolarHBondContact O-N 3.2Å; L152-A155 WeakPolarHBondContact O-CB 2.83Å; L152-A155 PolarHBondContact O-N 3.09Å; I153-A155 VanDerWaalsContact C-N 3.3Å; I153-A155 PolarHBondContact O-N 3.47Å; A155-P312 WeakPolarHBondContact CB-O 3.48Å; A155-A318 HydrophobicContact CB-CB 4.3Å
156	V	80.9	Confident	73.1	Confident	89 Å²	89	72.6 Å²	72.6	54%	0.539	44%	0.436	S	S	.	.	H	α-helix	trans	-72.4	-38.3	-179.9	177.2	0	0	0	0	111.5	L152 I153 A154 E159 T160	L152-V156 WeakPolarHBondContact O-CG2 3.29Å; L152-V156 PolarHBondContact O-N 3.4Å; I153-V156 PolarHBondContact O-N 3.01Å; A154-V156 PolarHBondContact O-N 3.03Å; V156-E159 PolarHBondContact O-N 3.49Å; V156-T160 PolarHBondContact O-OG1 3.39Å
157	A	75.6	Confident	72.1	Confident	49 Å²	49	77.3 Å²	77.3	41%	0.405	46%	0.458	S	S	.	.	H	α-helix	trans	-67.1	-36.9	-179.4	0	0	0	0	0	112.5	I153 A154 E159 T160 D161	I153-A157 VanDerWaalsContact O-CB 3.27Å; I153-A157 WeakPolarHBondContact O-CB 3.24Å; I153-A157 PolarHBondContact O-N 3.33Å; A154-A157 PolarHBondContact O-N 3.15Å; A157-E159 PolarHBondContact O-N 2.86Å; A157-T160 PolarHBondContact O-N 2.81Å; A157-D161 PolarHBondContact O-N 3.45Å
158	H	64.4	Low	71.3	Confident	143 Å²	143	85.1 Å²	85.1	66%	0.662	49%	0.486	S	S	*	.	H	α-helix	trans	-61.8	-27.4	175.5	-95.5	-72.5	0	0	0	113.6	A154 T160	A154-H158 WeakPolarHBondContact O-CB 3.19Å; A154-H158 PolarHBondContact O-CD2 3.03Å; A154-H158 VanDerWaalsContact O-CD2 3.32Å; A154-H158 PolarHBondContact O-N 3.3Å; H158-T160 VanDerWaalsContact C-N 3.28Å
159	E	56.4	Low	70.2	Confident	162 Å²	162	90.7 Å²	90.7	76%	0.757	51%	0.508	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76	-17.2	172.4	-65.6	-151.6	143.6	0	0	113.2	V156 A157	V156-E159 PolarHBondContact O-N 3.49Å; A157-E159 PolarHBondContact O-N 2.86Å
160	T	56.9	Low	69.3	Low	99 Å²	99	91.1 Å²	91.1	61%	0.607	51%	0.511	S	S	*	.	T	Hydrogen-bonded Turn	trans	-106	-34	-164.5	-39.5	0	0	0	0	114.3	V156 A157 H158	V156-T160 PolarHBondContact O-OG1 3.39Å; A157-T160 PolarHBondContact O-N 2.81Å; H158-T160 VanDerWaalsContact C-N 3.28Å
161	D	48.3	Very low	69	Low	134 Å²	134	92.3 Å²	92.3	72%	0.717	52%	0.518	S	S	*	.			trans	-173.8	144	171.2	-106.4	-31.9	0	0	0	115.3	A157 S163	A157-D161 PolarHBondContact O-N 3.45Å; D161-S163 PolarHBondContact O-N 3.4Å
162	G	50.2	Low	68.7	Low	89 Å²	89	90.6 Å²	90.6	92%	0.918	51%	0.511	S	S	*	.			trans	-76	51.2	172.5	0	0	0	0	0	114.3
163	S	49.6	Very low	68.5	Low	75 Å²	75	93.6 Å²	93.6	52%	0.524	52%	0.523	S	S	.	.			trans	-102.7	136	176.9	67.6	0	0	0	0	112.2	D161 E165	D161-S163 PolarHBondContact O-N 3.4Å; S163-E165 PolarHBondContact O-N 2.96Å
164	P	50.7	Low	68.5	Low	134 Å²	134	95.1 Å²	95.1	87%	0.87	53%	0.528	S	S	*	.	S	Bend	trans	-91.1	4	-165.7	-2.7	24.2	0	0	0	114.8
165	E	53.2	Low	68.6	Low	164 Å²	164	94.4 Å²	94.4	77%	0.766	52%	0.52	S	S	*	.	S	Bend	trans	-118.4	102.4	-174.7	-65.1	-169.8	174.8	0	0	110.4	S163 H167	S163-E165 PolarHBondContact O-N 2.96Å; E165-H167 PolarHBondContact O-N 3.43Å
166	G	60	Low	68.8	Low	70 Å²	70	93.8 Å²	93.8	72%	0.722	52%	0.515	S	S	*	.			trans	-57.5	122.7	176.4	0	0	0	0	0	111
167	H	71	Confident	69.3	Low	100 Å²	100	92.1 Å²	92.1	46%	0.463	51%	0.505	S	S	.	.			trans	-61.4	151.3	177.3	-68.9	-76.6	0	0	0	111.4	E165 Y169 T170	E165-H167 PolarHBondContact O-N 3.43Å; H167-Y169 HydrophobicContact CB-CD1 3.53Å; H167-Y169 HydrophobicContact CB-CE1 3.16Å; H167-Y169 HydrophobicContact CB-CE2 4.25Å; H167-Y169 HydrophobicContact CB-CG 4.22Å; H167-Y169 AromaticContact CD2-CE1 3.91Å; H167-Y169 AromaticContact CD2-CZ 3.74Å; H167-Y169 PolarHBondContact CD2-OH 3.41Å; H167-Y169 AromaticContact CG-CE1 3.45Å; H167-Y169 VanDerWaalsContact CG-CE1 3.45Å; H167-Y169 AromaticContact CG-CZ 3.74Å; H167-Y169 PolarHBondContact O-N 3.01Å; H167-T170 PolarHBondContact N-OG1 2.72Å; H167-T170 PolarHBondContact O-N 3.14Å; H167-T170 PolarHBondContact O-OG1 3.49Å
168	W	73.5	Confident	70	Confident	185 Å²	185	92.1 Å²	92.1	70%	0.701	50%	0.5	S	S	*	.	G	3₁₀ helix	trans	-56.1	-26.2	-179.8	64.9	-90.9	0	0	0	114.2	T170 D171 F174	W168-T170 VanDerWaalsContact C-N 3.32Å; W168-D171 PolarHBondContact O-N 3.26Å; W168-F174 HydrophobicContact CE3-CD2 4.45Å; W168-F174 HydrophobicContact CE3-CE1 4.46Å; W168-F174 HydrophobicContact CE3-CE2 4.33Å; W168-F174 HydrophobicContact CE3-CZ 4.33Å; W168-F174 HydrophobicContact CH2-CZ 4.18Å; W168-F174 HydrophobicContact CZ3-CD1 4.44Å; W168-F174 HydrophobicContact CZ3-CD2 4.19Å; W168-F174 AromaticContact CZ3-CE1 3.89Å; W168-F174 HydrophobicContact CZ3-CE1 3.89Å; W168-F174 AromaticContact CZ3-CE2 3.63Å; W168-F174 HydrophobicContact CZ3-CE2 3.63Å; W168-F174 AromaticContact CZ3-CZ 3.45Å; W168-F174 HydrophobicContact CZ3-CZ 3.45Å; W168-F174 VanDerWaalsContact CZ3-CZ 3.45Å
169	Y	70.6	Confident	71.1	Confident	116 Å²	116	86.5 Å²	86.5	46%	0.455	48%	0.476	S	S	.	.	G	3₁₀ helix	trans	-80.4	-11.8	179	63.9	-100.3	0	0	0	113.7	H167 F174	H167-Y169 HydrophobicContact CB-CD1 3.53Å; H167-Y169 HydrophobicContact CB-CE1 3.16Å; H167-Y169 HydrophobicContact CB-CE2 4.25Å; H167-Y169 HydrophobicContact CB-CG 4.22Å; H167-Y169 AromaticContact CD2-CE1 3.91Å; H167-Y169 AromaticContact CD2-CZ 3.74Å; H167-Y169 PolarHBondContact CD2-OH 3.41Å; H167-Y169 AromaticContact CG-CE1 3.45Å; H167-Y169 VanDerWaalsContact CG-CE1 3.45Å; H167-Y169 AromaticContact CG-CZ 3.74Å; H167-Y169 PolarHBondContact O-N 3.01Å; Y169-F174 WeakPolarHBondContact O-CD1 3.3Å
170	T	73.3	Confident	72.6	Confident	32 Å²	32	78.8 Å²	78.8	20%	0.196	44%	0.439	C	S	.	.	G	3₁₀ helix	trans	-94.6	-0.5	173.5	64.7	0	0	0	0	112.3	I153 H167 W168 R172	I153-T170 HydrophobicContact CG2-CG2 3.58Å; H167-T170 PolarHBondContact N-OG1 2.72Å; H167-T170 PolarHBondContact O-N 3.14Å; H167-T170 PolarHBondContact O-OG1 3.49Å; W168-T170 VanDerWaalsContact C-N 3.32Å; T170-R172 PolarHBondContact O-N 2.9Å
171	D	82.4	Confident	74.2	Confident	82 Å²	82	77.2 Å²	77.2	44%	0.439	43%	0.43	S	S	.	.			trans	-64.2	125.7	175.3	179.7	22	0	0	0	110.4	W168 K173 F174 T175	W168-D171 PolarHBondContact O-N 3.26Å; D171-K173 PolarHBondContact O-N 3.32Å; D171-K173 VanDerWaalsContact O-N 3.07Å; D171-K173 PolarHBondContact OD1-N 3.28Å; D171-F174 HydrophobicContact CB-CB 4.29Å; D171-F174 WeakPolarHBondContact O-CA 3.2Å; D171-F174 WeakPolarHBondContact O-CB 3.38Å; D171-F174 PolarHBondContact O-N 3.44Å; D171-T175 PolarHBondContact O-N 2.78Å; D171-T175 PolarHBondContact O-OG1 3.26Å
172	R	82.3	Confident	76.1	Confident	45 Å²	45	76.7 Å²	76.7	17%	0.17	43%	0.426	C	S	.	.	H	α-helix	trans	-45.8	-43.4	178.5	178.4	178.1	176.6	-85.4	5	112	D147 D150 T170 T175 I176	D147-R172 IonicContact OD1-CZ 3Å; D147-R172 IonicContact OD1-NE 3.05Å; D147-R172 PolarHBondContact OD1-NE 2.84Å; D147-R172 IonicContact OD1-NH2 2.66Å; D147-R172 PolarHBondContact OD1-NH2 2.78Å; D150-R172 HydrophobicContact CB-CB 4.43Å; D150-R172 HydrophobicContact CB-CG 4.46Å; T170-R172 PolarHBondContact O-N 2.9Å; R172-T175 PolarHBondContact O-N 3.03Å; R172-I176 HydrophobicContact CG-CD1 3.93Å; R172-I176 WeakPolarHBondContact O-CD1 3.33Å; R172-I176 WeakPolarHBondContact O-CG1 3.47Å; R172-I176 PolarHBondContact O-N 3.36Å
173	K	85.7	Confident	77.9	Confident	106 Å²	106	75.4 Å²	75.4	46%	0.461	40%	0.401	S	S	.	.	H	α-helix	trans	-64.2	-43.6	-179.6	-66.4	-178.7	179.9	175.7	0	111.8	D171 V177 L382	D171-K173 PolarHBondContact O-N 3.32Å; D171-K173 VanDerWaalsContact O-N 3.07Å; D171-K173 PolarHBondContact OD1-N 3.28Å; K173-V177 VanDerWaalsContact O-CG2 3.3Å; K173-V177 WeakPolarHBondContact O-CG2 3.32Å; K173-V177 PolarHBondContact O-N 2.89Å; K173-V177 VanDerWaalsContact O-N 3.17Å; K173-L382 HydrophobicContact CB-CD2 4.03Å; K173-L382 HydrophobicContact CG-CD2 4.14Å
174	F	86.8	Confident	79.8	Confident	80 Å²	80	71.9 Å²	71.9	35%	0.351	38%	0.376	S	S	.	.	H	α-helix	trans	-64	-46.4	177.5	178.9	-101.4	0	0	0	111.2	W168 Y169 D171 I176 V177 V178	W168-F174 HydrophobicContact CE3-CD2 4.45Å; W168-F174 HydrophobicContact CE3-CE1 4.46Å; W168-F174 HydrophobicContact CE3-CE2 4.33Å; W168-F174 HydrophobicContact CE3-CZ 4.33Å; W168-F174 HydrophobicContact CH2-CZ 4.18Å; W168-F174 HydrophobicContact CZ3-CD1 4.44Å; W168-F174 HydrophobicContact CZ3-CD2 4.19Å; W168-F174 AromaticContact CZ3-CE1 3.89Å; W168-F174 HydrophobicContact CZ3-CE1 3.89Å; W168-F174 AromaticContact CZ3-CE2 3.63Å; W168-F174 HydrophobicContact CZ3-CE2 3.63Å; W168-F174 AromaticContact CZ3-CZ 3.45Å; W168-F174 HydrophobicContact CZ3-CZ 3.45Å; W168-F174 VanDerWaalsContact CZ3-CZ 3.45Å; Y169-F174 WeakPolarHBondContact O-CD1 3.3Å; D171-F174 HydrophobicContact CB-CB 4.29Å; D171-F174 WeakPolarHBondContact O-CA 3.2Å; D171-F174 WeakPolarHBondContact O-CB 3.38Å; D171-F174 PolarHBondContact O-N 3.44Å; F174-I176 PolarHBondContact O-N 2.88Å; F174-V177 PolarHBondContact O-N 3.14Å; F174-V178 HydrophobicContact CD1-CG2 4.09Å; F174-V178 HydrophobicContact CD2-CG2 4.23Å; F174-V178 HydrophobicContact CE1-CG2 3.63Å; F174-V178 HydrophobicContact CE2-CG2 3.76Å; F174-V178 HydrophobicContact CG-CG2 4.38Å; F174-V178 HydrophobicContact CZ-CG2 3.44Å; F174-V178 VanDerWaalsContact CZ-CG2 3.44Å; F174-V178 WeakPolarHBondContact O-CG2 3.33Å; F174-V178 PolarHBondContact O-N 2.97Å
175	T	86.6	Confident	81.5	Confident	15 Å²	15	66.8 Å²	66.8	9%	0.092	34%	0.341	C	S	.	.	H	α-helix	trans	-63.1	-39.7	-179.6	-51.1	0	0	0	0	112.8	L149 I153 D171 R172 T179	L149-T175 HydrophobicContact CB-CG2 3.73Å; L149-T175 HydrophobicContact CD1-CG2 3.63Å; L149-T175 HydrophobicContact CG-CG2 4.24Å; I153-T175 HydrophobicContact CD1-CG2 3.82Å; D171-T175 PolarHBondContact O-N 2.78Å; D171-T175 PolarHBondContact O-OG1 3.26Å; R172-T175 PolarHBondContact O-N 3.03Å; T175-T179 WeakPolarHBondContact O-CB 3.27Å; T175-T179 PolarHBondContact O-N 3.43Å; T175-T179 PolarHBondContact O-OG1 3Å
176	I	87.4	Confident	83	Confident	0 Å²	0	62.1 Å²	62.1	0%	0	33%	0.325	C	S	.	.	H	α-helix	trans	-59.6	-50.9	173	-67.2	164.8	0	0	0	109.9	F142 R172 F174 V178 T179 A180 L378 L382	F142-I176 HydrophobicContact CB-CG2 4.38Å; F142-I176 HydrophobicContact CD1-CG2 4.26Å; R172-I176 HydrophobicContact CG-CD1 3.93Å; R172-I176 WeakPolarHBondContact O-CD1 3.33Å; R172-I176 WeakPolarHBondContact O-CG1 3.47Å; R172-I176 PolarHBondContact O-N 3.36Å; F174-I176 PolarHBondContact O-N 2.88Å; I176-V178 PolarHBondContact O-N 3.38Å; I176-T179 PolarHBondContact O-N 3.36Å; I176-A180 WeakPolarHBondContact O-CB 3.39Å; I176-A180 PolarHBondContact O-N 3.27Å; I176-L378 HydrophobicContact CG2-CD1 3.65Å; I176-L382 HydrophobicContact CB-CD2 4.23Å; I176-L382 HydrophobicContact CD1-CD2 4.16Å; I176-L382 HydrophobicContact CG2-CD2 4.2Å
177	V	90	Very high	84	Confident	54 Å²	54	61.9 Å²	61.9	33%	0.327	31%	0.307	S	S	.	.	H	α-helix	trans	-61.8	-44.8	-177.2	172	0	0	0	0	111.4	K173 F174 A180 V181 L378 L382	K173-V177 VanDerWaalsContact O-CG2 3.3Å; K173-V177 WeakPolarHBondContact O-CG2 3.32Å; K173-V177 PolarHBondContact O-N 2.89Å; K173-V177 VanDerWaalsContact O-N 3.17Å; F174-V177 PolarHBondContact O-N 3.14Å; V177-A180 PolarHBondContact O-N 3.41Å; V177-V181 HydrophobicContact CG1-CG2 4.35Å; V177-V181 WeakPolarHBondContact O-CB 3.29Å; V177-V181 VanDerWaalsContact O-CG2 3.31Å; V177-V181 WeakPolarHBondContact O-CG2 3.31Å; V177-V181 PolarHBondContact O-N 3.45Å; V177-L378 HydrophobicContact CG2-CD1 4.43Å; V177-L378 HydrophobicContact CG2-CD2 4.42Å; V177-L382 HydrophobicContact CG2-CD1 4.02Å; V177-L382 HydrophobicContact CG2-CD2 4.35Å
178	V	90.4	Very high	84.4	Confident	50 Å²	50	57.4 Å²	57.4	30%	0.303	29%	0.287	S	S	.	.	H	α-helix	trans	-62.2	-50.7	179.3	170.4	0	0	0	0	111	F174 I176 A180 V181 L182	F174-V178 HydrophobicContact CD1-CG2 4.09Å; F174-V178 HydrophobicContact CD2-CG2 4.23Å; F174-V178 HydrophobicContact CE1-CG2 3.63Å; F174-V178 HydrophobicContact CE2-CG2 3.76Å; F174-V178 HydrophobicContact CG-CG2 4.38Å; F174-V178 HydrophobicContact CZ-CG2 3.44Å; F174-V178 VanDerWaalsContact CZ-CG2 3.44Å; F174-V178 WeakPolarHBondContact O-CG2 3.33Å; F174-V178 PolarHBondContact O-N 2.97Å; I176-V178 PolarHBondContact O-N 3.38Å; V178-A180 VanDerWaalsContact C-N 3.32Å; V178-A180 PolarHBondContact O-N 3.39Å; V178-V181 PolarHBondContact O-N 2.76Å; V178-L182 HydrophobicContact CG1-CD1 3.71Å; V178-L182 HydrophobicContact CG1-CG 4.32Å; V178-L182 VanDerWaalsContact O-CB 3.27Å; V178-L182 WeakPolarHBondContact O-CB 3.3Å; V178-L182 WeakPolarHBondContact O-CG 3.23Å; V178-L182 PolarHBondContact O-N 3.35Å
179	T	87.5	Confident	84.3	Confident	24 Å²	24	53.3 Å²	53.3	15%	0.147	28%	0.277	C	S	.	.	H	α-helix	trans	-63.1	-40.8	178.8	-57.9	0	0	0	0	111.4	I145 L149 T175 I176 V183 I184 V329	I145-T179 HydrophobicContact CG2-CG2 4.04Å; L149-T179 HydrophobicContact CD1-CG2 4.2Å; L149-T179 VanDerWaalsContact CD1-OG1 3.3Å; L149-T179 WeakPolarHBondContact CD1-OG1 3.46Å; T175-T179 WeakPolarHBondContact O-CB 3.27Å; T175-T179 PolarHBondContact O-N 3.43Å; T175-T179 PolarHBondContact O-OG1 3Å; I176-T179 PolarHBondContact O-N 3.36Å; T179-V183 HydrophobicContact CG2-CB 4.44Å; T179-V183 HydrophobicContact CG2-CG2 4.4Å; T179-V183 WeakPolarHBondContact O-CA 3.49Å; T179-V183 VanDerWaalsContact O-CB 3.26Å; T179-V183 WeakPolarHBondContact O-CB 3.44Å; T179-V183 PolarHBondContact O-N 3.02Å; T179-I184 PolarHBondContact O-N 2.78Å; T179-V329 HydrophobicContact CG2-CG2 4.42Å
180	A	88.3	Confident	84.1	Confident	0 Å²	0	51.3 Å²	51.3	0%	0	28%	0.279	C	S	.	.	I	π-helix	trans	-60.6	-49.6	177.8	0	0	0	0	0	111.5	F142 I176 V177 V178 I184 L185 F374 L378	F142-A180 HydrophobicContact CD1-CB 4.16Å; F142-A180 HydrophobicContact CE1-CB 3.39Å; F142-A180 HydrophobicContact CZ-CB 4.03Å; I176-A180 WeakPolarHBondContact O-CB 3.39Å; I176-A180 PolarHBondContact O-N 3.27Å; V177-A180 PolarHBondContact O-N 3.41Å; V178-A180 VanDerWaalsContact C-N 3.32Å; V178-A180 PolarHBondContact O-N 3.39Å; A180-I184 WeakPolarHBondContact O-CB 3.28Å; A180-I184 PolarHBondContact O-N 3.26Å; A180-L185 WeakPolarHBondContact O-CB 3.32Å; A180-L185 PolarHBondContact O-N 2.67Å; A180-F374 HydrophobicContact CB-CE2 4.16Å; A180-F374 HydrophobicContact CB-CZ 3.65Å; A180-F374 WeakPolarHBondContact O-CZ 3.44Å; A180-L378 HydrophobicContact CB-CD1 4.01Å; A180-L378 HydrophobicContact CB-CD2 4.31Å
181	V	90.2	Very high	83.3	Confident	66 Å²	66	54.7 Å²	54.7	40%	0.4	29%	0.291	S	S	.	.	I	π-helix	trans	-76.9	-39.2	-174.8	174.3	0	0	0	0	112.2	V177 V178 P186 F374	V177-V181 HydrophobicContact CG1-CG2 4.35Å; V177-V181 WeakPolarHBondContact O-CB 3.29Å; V177-V181 VanDerWaalsContact O-CG2 3.31Å; V177-V181 WeakPolarHBondContact O-CG2 3.31Å; V177-V181 PolarHBondContact O-N 3.45Å; V178-V181 PolarHBondContact O-N 2.76Å; V181-P186 VanDerWaalsContact O-CD 3.26Å; V181-P186 WeakPolarHBondContact O-CD 3.22Å; V181-F374 HydrophobicContact CG2-CE1 4.45Å
182	L	89.3	Confident	82	Confident	124 Å²	124	56.6 Å²	56.6	65%	0.649	30%	0.297	S	S	*	.	I	π-helix	trans	-86.7	-25.5	-175.2	-62.4	-174.7	0	0	0	113.8	V178 P186	V178-L182 HydrophobicContact CG1-CD1 3.71Å; V178-L182 HydrophobicContact CG1-CG 4.32Å; V178-L182 VanDerWaalsContact O-CB 3.27Å; V178-L182 WeakPolarHBondContact O-CB 3.3Å; V178-L182 WeakPolarHBondContact O-CG 3.23Å; V178-L182 PolarHBondContact O-N 3.35Å; L182-P186 WeakPolarHBondContact O-CG 3.27Å
183	V	88.2	Confident	80.8	Confident	62 Å²	62	57.5 Å²	57.5	38%	0.376	31%	0.305	S	S	.	.	I	π-helix	trans	-116.5	-57.6	-174.6	-168.9	0	0	0	0	111.1	T179 P186 L187 V329	T179-V183 HydrophobicContact CG2-CB 4.44Å; T179-V183 HydrophobicContact CG2-CG2 4.4Å; T179-V183 WeakPolarHBondContact O-CA 3.49Å; T179-V183 VanDerWaalsContact O-CB 3.26Å; T179-V183 WeakPolarHBondContact O-CB 3.44Å; T179-V183 PolarHBondContact O-N 3.02Å; V183-P186 WeakPolarHBondContact O-CD 3.29Å; V183-L187 HydrophobicContact CG1-CD1 3.95Å; V183-L187 WeakPolarHBondContact O-CB 3.34Å; V183-L187 WeakPolarHBondContact O-CD1 3.4Å; V183-L187 VanDerWaalsContact O-CG 3.23Å; V183-L187 WeakPolarHBondContact O-CG 3.24Å; V183-L187 PolarHBondContact O-N 3.39Å; V183-V329 HydrophobicContact CG1-CG1 3.59Å
184	I	87.8	Confident	79.3	Confident	0 Å²	0	55.9 Å²	55.9	0%	0	31%	0.307	C	S	.	.	I	π-helix	trans	-70.3	-45	-172	-65	170.7	0	0	0	112.1	F142 I145 T179 A180 L187 S188 V329 Y332 F374	F142-I184 HydrophobicContact CD1-CD1 4.11Å; F142-I184 HydrophobicContact CE1-CD1 3.6Å; I145-I184 HydrophobicContact CD1-CD1 3.48Å; I145-I184 VanDerWaalsContact CD1-CD1 3.48Å; T179-I184 PolarHBondContact O-N 2.78Å; A180-I184 WeakPolarHBondContact O-CB 3.28Å; A180-I184 PolarHBondContact O-N 3.26Å; I184-L187 CarbonylContact O-C 3.33Å; I184-L187 PolarHBondContact O-N 3.03Å; I184-S188 WeakPolarHBondContact O-CB 3.31Å; I184-S188 PolarHBondContact O-N 3.39Å; I184-S188 PolarHBondContact O-OG 3.41Å; I184-V329 HydrophobicContact CD1-CG2 4.25Å; I184-V329 HydrophobicContact CG1-CG1 4.23Å; I184-V329 HydrophobicContact CG1-CG2 4.1Å; I184-Y332 HydrophobicContact CG2-CD1 3.23Å; I184-Y332 HydrophobicContact CG2-CD2 4.25Å; I184-Y332 HydrophobicContact CG2-CE1 3.57Å; I184-Y332 HydrophobicContact CG2-CG 3.63Å; I184-F374 HydrophobicContact CB-CE2 4.36Å; I184-F374 HydrophobicContact CG2-CE2 4.08Å
185	L	86.2	Confident	78.1	Confident	28 Å²	28	58.9 Å²	58.9	15%	0.147	32%	0.32	C	S	.	.	H	α-helix	trans	-62.4	-48.5	-177.4	177.8	66.1	0	0	0	111.7	A180 L187 S188 I189 L371 F374	A180-L185 WeakPolarHBondContact O-CB 3.32Å; A180-L185 PolarHBondContact O-N 2.67Å; L185-L187 VanDerWaalsContact C-N 3.28Å; L185-L187 PolarHBondContact O-N 3.39Å; L185-S188 PolarHBondContact O-N 2.9Å; L185-I189 WeakPolarHBondContact O-CG1 3.25Å; L185-I189 PolarHBondContact O-N 3.3Å; L185-L371 HydrophobicContact CD1-CD2 4.09Å; L185-L371 HydrophobicContact CD2-CD2 4.43Å; L185-F374 HydrophobicContact CB-CD2 4.45Å; L185-F374 HydrophobicContact CB-CE1 4.38Å; L185-F374 HydrophobicContact CB-CE2 3.91Å; L185-F374 HydrophobicContact CB-CZ 3.87Å; L185-F374 HydrophobicContact CD1-CD1 4.3Å; L185-F374 HydrophobicContact CD1-CD2 4.28Å; L185-F374 HydrophobicContact CD1-CG 4.16Å; L185-F374 HydrophobicContact CD2-CE1 4.47Å
186	P	85.2	Confident	76.9	Confident	66 Å²	66	59.4 Å²	59.4	43%	0.429	32%	0.321	S	S	.	.	H	α-helix	trans	-57.2	-39	172.8	-28.4	36.5	0	0	0	113.3	V181 L182 V183 S188 P190	V181-P186 VanDerWaalsContact O-CD 3.26Å; V181-P186 WeakPolarHBondContact O-CD 3.22Å; L182-P186 WeakPolarHBondContact O-CG 3.27Å; V183-P186 WeakPolarHBondContact O-CD 3.29Å; P186-S188 VanDerWaalsContact C-N 3.28Å; P186-S188 PolarHBondContact O-N 3.08Å; P186-P190 WeakPolarHBondContact O-CD 3.15Å
187	L	81.2	Confident	76	Confident	64 Å²	64	64.8 Å²	64.8	34%	0.335	34%	0.344	S	S	.	.	H	α-helix	trans	-71.3	-20.4	177.4	-71	171.1	0	0	0	113.6	V183 I184 L185 P190 V329 P333	V183-L187 HydrophobicContact CG1-CD1 3.95Å; V183-L187 WeakPolarHBondContact O-CB 3.34Å; V183-L187 WeakPolarHBondContact O-CD1 3.4Å; V183-L187 VanDerWaalsContact O-CG 3.23Å; V183-L187 WeakPolarHBondContact O-CG 3.24Å; V183-L187 PolarHBondContact O-N 3.39Å; I184-L187 CarbonylContact O-C 3.33Å; I184-L187 PolarHBondContact O-N 3.03Å; L185-L187 VanDerWaalsContact C-N 3.28Å; L185-L187 PolarHBondContact O-N 3.39Å; L187-P190 WeakPolarHBondContact O-CD 3.5Å; L187-V329 HydrophobicContact CD1-CG1 3.73Å; L187-P333 HydrophobicContact CB-CG 3.78Å; L187-P333 WeakPolarHBondContact O-CB 3.41Å
188	S	79.3	Confident	75.2	Confident	6 Å²	6	69.4 Å²	69.4	4%	0.042	36%	0.357	C	S	.	.	H	α-helix	trans	-91.6	-9.6	-177.9	-57.8	0	0	0	0	114.1	I184 L185 P186	I184-S188 WeakPolarHBondContact O-CB 3.31Å; I184-S188 PolarHBondContact O-N 3.39Å; I184-S188 PolarHBondContact O-OG 3.41Å; L185-S188 PolarHBondContact O-N 2.9Å; P186-S188 VanDerWaalsContact C-N 3.28Å; P186-S188 PolarHBondContact O-N 3.08Å
189	I	71.1	Confident	74.6	Confident	99 Å²	99	67.5 Å²	67.5	51%	0.508	35%	0.347	S	S	.	.	S	Bend	trans	-79.7	-39.8	179.6	-67.4	165.4	0	0	0	113.6	L185	L185-I189 WeakPolarHBondContact O-CG1 3.25Å; L185-I189 PolarHBondContact O-N 3.3Å
190	P	66.8	Low	74.1	Confident	74 Å²	74	66.4 Å²	66.4	48%	0.481	34%	0.34	S	S	.	.			trans	-54.6	146.9	-178	-28.1	34.4	0	0	0	113.6	P186 L187	P186-P190 WeakPolarHBondContact O-CD 3.15Å; L187-P190 WeakPolarHBondContact O-CD 3.5Å
191	K	56.1	Low	73.8	Confident	103 Å²	103	68.1 Å²	68.1	45%	0.448	35%	0.354	S	S	.	.	S	Bend	trans	-84.6	-17.8	177.9	-56.1	-161.4	169.9	-165.7	0	112.8	E362	K191-E362 IonicContact NZ-OE2 3.73Å; K191-E362 PolarHBondContact NZ-OE2 2.93Å
192	E	55.8	Low	73.5	Confident	122 Å²	122	68.4 Å²	68.4	57%	0.57	35%	0.353	S	S	*	.			trans	-108.3	134.8	-169.6	-70.3	-169.6	-156.6	0	0	114	S194	E192-S194 PolarHBondContact O-N 3.1Å; E192-S194 PolarHBondContact OE2-OG 2.88Å
193	I	56.9	Low	73.3	Confident	65 Å²	65	62.6 Å²	62.6	33%	0.333	32%	0.322	S	S	.	.			trans	-78.9	-3.7	173.6	-67.5	169.7	0	0	0	111.5	F195 Q196 F337	I193-F195 VanDerWaalsContact C-N 3.3Å; I193-F195 PolarHBondContact O-N 2.9Å; I193-F195 VanDerWaalsContact O-N 3.15Å; I193-Q196 HydrophobicContact CG2-CB 3.99Å; I193-Q196 WeakPolarHBondContact O-CB 3.27Å; I193-Q196 PolarHBondContact O-N 2.92Å; I193-F337 HydrophobicContact CD1-CE1 4.35Å
194	S	55.1	Low	73.1	Confident	72 Å²	72	60.1 Å²	60.1	50%	0.503	31%	0.308	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.3	-32	-169.1	-52.9	0	0	0	0	114.8	E192 Q196	E192-S194 PolarHBondContact O-N 3.1Å; E192-S194 PolarHBondContact OE2-OG 2.88Å; S194-Q196 VanDerWaalsContact C-N 3.31Å
195	F	61.4	Low	73.2	Confident	143 Å²	143	66.2 Å²	66.2	63%	0.627	34%	0.338	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.1	-21	175.7	-177.3	-106.7	0	0	0	112.9	I193 K197 Y198	I193-F195 VanDerWaalsContact C-N 3.3Å; I193-F195 PolarHBondContact O-N 2.9Å; I193-F195 VanDerWaalsContact O-N 3.15Å; F195-K197 VanDerWaalsContact C-N 3.3Å; F195-K197 PolarHBondContact O-N 2.95Å; F195-Y198 PolarHBondContact O-N 3.5Å
196	Q	61.7	Low	73.4	Confident	25 Å²	25	64.9 Å²	64.9	12%	0.117	33%	0.331	C	S	.	.	H	α-helix	trans	-66.9	-27.1	-169.4	-162.2	-175.6	-57.3	0	0	113.2	I193 S194 Y198 A199 S200 I334	I193-Q196 HydrophobicContact CG2-CB 3.99Å; I193-Q196 WeakPolarHBondContact O-CB 3.27Å; I193-Q196 PolarHBondContact O-N 2.92Å; S194-Q196 VanDerWaalsContact C-N 3.31Å; Q196-Y198 VanDerWaalsContact C-N 3.26Å; Q196-Y198 PolarHBondContact O-N 2.86Å; Q196-A199 PolarHBondContact O-N 3.49Å; Q196-S200 WeakPolarHBondContact O-CB 3.46Å; Q196-S200 PolarHBondContact O-N 2.91Å; Q196-S200 PolarHBondContact O-OG 3.42Å; Q196-I334 HydrophobicContact CG-CD1 3.8Å; Q196-I334 HydrophobicContact CG-CG1 4.11Å; Q196-I334 VanDerWaalsContact OE1-CG1 3.31Å
197	K	67.8	Low	73.7	Confident	113 Å²	113	61.7 Å²	61.7	49%	0.491	31%	0.31	S	S	.	.	H	α-helix	trans	-60.4	-35.3	177.7	69.5	-175.3	-178.7	-178.8	0	112.9	F195 A201	F195-K197 VanDerWaalsContact C-N 3.3Å; F195-K197 PolarHBondContact O-N 2.95Å; K197-A201 PolarHBondContact O-N 3.14Å
198	Y	73.8	Confident	74.3	Confident	152 Å²	152	63.5 Å²	63.5	60%	0.596	31%	0.313	S	S	*	.	H	α-helix	trans	-76.2	-40.9	177.8	-62.8	-73.5	0	0	0	110.8	F195 Q196 S200 A201 L202	F195-Y198 PolarHBondContact O-N 3.5Å; Q196-Y198 VanDerWaalsContact C-N 3.26Å; Q196-Y198 PolarHBondContact O-N 2.86Å; Y198-S200 VanDerWaalsContact C-N 3.34Å; Y198-S200 PolarHBondContact O-N 3.13Å; Y198-A201 PolarHBondContact O-N 2.88Å; Y198-L202 PolarHBondContact O-N 3.43Å
199	A	76.3	Confident	75	Confident	10 Å²	10	66.2 Å²	66.2	8%	0.083	32%	0.322	C	S	.	.	H	α-helix	trans	-62.3	-39.8	174.2	0	0	0	0	0	112.3	Q196 L202 S203 T330	Q196-A199 PolarHBondContact O-N 3.49Å; A199-L202 PolarHBondContact O-N 2.84Å; A199-S203 WeakPolarHBondContact O-CB 3.43Å; A199-S203 PolarHBondContact O-N 3.31Å; A199-T330 HydrophobicContact CB-CG2 3.75Å
200	S	77.3	Confident	76.1	Confident	0 Å²	0	61.5 Å²	61.5	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-62	-41.9	175.1	-69	0	0	0	0	112.3	N57 Q196 Y198 S203 V204	N57-S200 PolarHBondContact ND2-OG 3.26Å; Q196-S200 WeakPolarHBondContact O-CB 3.46Å; Q196-S200 PolarHBondContact O-N 2.91Å; Q196-S200 PolarHBondContact O-OG 3.42Å; Y198-S200 VanDerWaalsContact C-N 3.34Å; Y198-S200 PolarHBondContact O-N 3.13Å; S200-S203 PolarHBondContact O-N 3.21Å; S200-V204 WeakPolarHBondContact O-CB 3.45Å; S200-V204 VanDerWaalsContact O-CG2 3.25Å; S200-V204 WeakPolarHBondContact O-CG2 3.48Å; S200-V204 PolarHBondContact O-N 3.03Å
201	A	82.4	Confident	77.5	Confident	36 Å²	36	58.1 Å²	58.1	30%	0.298	28%	0.276	S	S	.	.	H	α-helix	trans	-63	-45	176.8	0	0	0	0	0	111.7	K197 Y198 V204 M205	K197-A201 PolarHBondContact O-N 3.14Å; Y198-A201 PolarHBondContact O-N 2.88Å; A201-V204 PolarHBondContact O-N 3.28Å; A201-M205 WeakPolarHBondContact O-CG 3.43Å; A201-M205 PolarHBondContact O-N 3.43Å
202	L	84.4	Confident	79.4	Confident	73 Å²	73	57.5 Å²	57.5	38%	0.382	28%	0.277	S	S	.	.	H	α-helix	trans	-63	-43	177.6	-177.9	62	0	0	0	112.1	Y198 A199 M205 G206 F323 I326	Y198-L202 PolarHBondContact O-N 3.43Å; A199-L202 PolarHBondContact O-N 2.84Å; L202-M205 PolarHBondContact O-N 3.19Å; L202-G206 PolarHBondContact O-N 2.87Å; L202-F323 HydrophobicContact CD1-CE1 4.33Å; L202-I326 HydrophobicContact CD2-CG2 3.7Å; L202-I326 HydrophobicContact CG-CG2 4.19Å
203	S	83.4	Confident	81.2	Confident	1 Å²	1	52.1 Å²	52.1	1%	0.007	25%	0.252	C	S	.	.	H	α-helix	trans	-62	-45.6	176.1	172.2	0	0	0	0	112.2	N57 A199 S200 M205 G206 T207 C327	N57-S203 WeakPolarHBondContact OD1-CB 3.27Å; N57-S203 PolarHBondContact OD1-OG 2.91Å; A199-S203 WeakPolarHBondContact O-CB 3.43Å; A199-S203 PolarHBondContact O-N 3.31Å; S200-S203 PolarHBondContact O-N 3.21Å; S203-M205 VanDerWaalsContact C-N 3.33Å; S203-M205 PolarHBondContact O-N 3.05Å; S203-G206 PolarHBondContact O-N 3.46Å; S203-G206 VanDerWaalsContact O-N 3.13Å; S203-T207 WeakPolarHBondContact O-CG2 3.48Å; S203-T207 PolarHBondContact O-N 3.47Å; S203-T207 PolarHBondContact O-OG1 3.23Å; S203-C327 PolarHBondContact OG-SG 3.17Å
204	V	85.9	Confident	83	Confident	11 Å²	11	49 Å²	49	7%	0.067	24%	0.236	C	C	.	.	H	α-helix	trans	-61	-42.5	175.4	172.5	0	0	0	0	111.2	F53 V56 N57 S200 A201 G206 T207 W208	F53-V204 HydrophobicContact CD1-CB 4.33Å; F53-V204 HydrophobicContact CD1-CG1 4.33Å; F53-V204 HydrophobicContact CD1-CG2 4.25Å; F53-V204 HydrophobicContact CE1-CG1 4.35Å; V56-V204 HydrophobicContact CB-CG2 4.15Å; V56-V204 HydrophobicContact CG1-CG1 4.19Å; V56-V204 HydrophobicContact CG1-CG2 3.66Å; N57-V204 HydrophobicContact CB-CG2 4.37Å; S200-V204 WeakPolarHBondContact O-CB 3.45Å; S200-V204 VanDerWaalsContact O-CG2 3.25Å; S200-V204 WeakPolarHBondContact O-CG2 3.48Å; S200-V204 PolarHBondContact O-N 3.03Å; A201-V204 PolarHBondContact O-N 3.28Å; V204-G206 VanDerWaalsContact C-N 3.34Å; V204-G206 PolarHBondContact O-N 3.36Å; V204-T207 WeakPolarHBondContact CA-OG1 3.3Å; V204-T207 PolarHBondContact O-N 3.41Å; V204-T207 PolarHBondContact O-OG1 3.43Å; V204-W208 PolarHBondContact O-N 2.95Å; V204-W208 VanDerWaalsContact O-N 3.13Å
205	M	89.9	Confident	84.9	Confident	127 Å²	127	48.3 Å²	48.3	63%	0.626	23%	0.226	S	C	*	.	H	α-helix	trans	-60.9	-43.2	173.8	-71.3	175.6	57	0	0	112.3	A201 L202 S203 W208 Y209	A201-M205 WeakPolarHBondContact O-CG 3.43Å; A201-M205 PolarHBondContact O-N 3.43Å; L202-M205 PolarHBondContact O-N 3.19Å; S203-M205 VanDerWaalsContact C-N 3.33Å; S203-M205 PolarHBondContact O-N 3.05Å; M205-W208 PolarHBondContact O-N 3.2Å; M205-Y209 PolarHBondContact O-N 2.99Å
206	G	90.5	Very high	86.4	Confident	0 Å²	0	45 Å²	45	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-62.1	-42.4	177.8	0	0	0	0	0	113.3	L202 S203 V204 W208 Y209 V210 F323	L202-G206 PolarHBondContact O-N 2.87Å; S203-G206 PolarHBondContact O-N 3.46Å; S203-G206 VanDerWaalsContact O-N 3.13Å; V204-G206 VanDerWaalsContact C-N 3.34Å; V204-G206 PolarHBondContact O-N 3.36Å; G206-W208 PolarHBondContact O-N 2.79Å; G206-Y209 WeakPolarHBondContact O-CB 3.44Å; G206-Y209 PolarHBondContact O-N 3.41Å; G206-V210 VanDerWaalsContact O-CG2 3.25Å; G206-V210 WeakPolarHBondContact O-CG2 3.41Å; G206-V210 PolarHBondContact O-N 3.2Å; G206-F323 VanDerWaalsContact CA-CD1 3.48Å
207	T	90.4	Very high	87.8	Confident	0 Å²	0	44.8 Å²	44.8	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-66.5	-36.4	177.6	58.1	0	0	0	0	112.7	L60 L64 S203 V204 V210 T211	L60-T207 HydrophobicContact CB-CG2 4Å; L60-T207 WeakPolarHBondContact CD1-OG1 3.31Å; L60-T207 WeakPolarHBondContact O-CG2 3.24Å; L64-T207 HydrophobicContact CD2-CG2 4.4Å; S203-T207 WeakPolarHBondContact O-CG2 3.48Å; S203-T207 PolarHBondContact O-N 3.47Å; S203-T207 PolarHBondContact O-OG1 3.23Å; V204-T207 WeakPolarHBondContact CA-OG1 3.3Å; V204-T207 PolarHBondContact O-N 3.41Å; V204-T207 PolarHBondContact O-OG1 3.43Å; T207-V210 PolarHBondContact O-N 3.44Å; T207-T211 PolarHBondContact O-N 2.86Å; T207-T211 PolarHBondContact O-OG1 3.49Å
208	W	93.6	Very high	88.8	Confident	102 Å²	102	43.8 Å²	43.8	39%	0.386	21%	0.21	S	C	.	.	H	α-helix	trans	-64.5	-42.3	169.7	-90.1	100.1	0	0	0	112.1	V204 M205 G206 V210 T211 I212 I282 F285 V286	V204-W208 PolarHBondContact O-N 2.95Å; V204-W208 VanDerWaalsContact O-N 3.13Å; M205-W208 PolarHBondContact O-N 3.2Å; G206-W208 PolarHBondContact O-N 2.79Å; W208-V210 PolarHBondContact O-N 3.06Å; W208-T211 WeakPolarHBondContact O-CB 3.23Å; W208-T211 PolarHBondContact O-N 2.93Å; W208-I212 VanDerWaalsContact O-CG1 3.25Å; W208-I212 WeakPolarHBondContact O-CG1 3.14Å; W208-I212 PolarHBondContact O-N 3.09Å; W208-I282 HydrophobicContact CZ2-CG2 4.43Å; W208-F285 HydrophobicContact CH2-CB 4.44Å; W208-V286 HydrophobicContact CD2-CG2 3.88Å; W208-V286 HydrophobicContact CE3-CG2 4.33Å; W208-V286 HydrophobicContact CG-CG2 4.36Å; W208-V286 HydrophobicContact CH2-CG2 4.19Å; W208-V286 HydrophobicContact CZ2-CG2 3.72Å; W208-V286 HydrophobicContact CZ3-CG2 4.47Å
209	Y	94.9	Very high	89.6	Confident	63 Å²	63	41.3 Å²	41.3	25%	0.247	21%	0.206	C	C	.	.	H	α-helix	trans	-58.6	-47.8	175.1	179	-94.1	0	0	0	111.5	M205 G206 T211 I212 V213 A316 L319 A320 F323	M205-Y209 PolarHBondContact O-N 2.99Å; G206-Y209 WeakPolarHBondContact O-CB 3.44Å; G206-Y209 PolarHBondContact O-N 3.41Å; Y209-T211 VanDerWaalsContact C-N 3.31Å; Y209-T211 PolarHBondContact O-N 3.45Å; Y209-I212 PolarHBondContact O-N 2.97Å; Y209-V213 HydrophobicContact CD1-CG2 4.06Å; Y209-V213 HydrophobicContact CE1-CG2 3.58Å; Y209-V213 HydrophobicContact CE2-CG2 4.19Å; Y209-V213 WeakPolarHBondContact O-CG2 3.46Å; Y209-V213 PolarHBondContact O-N 3.22Å; Y209-A316 PolarHBondContact OH-O 3.01Å; Y209-L319 HydrophobicContact CE1-CB 3.76Å; Y209-L319 WeakPolarHBondContact OH-CB 3.46Å; Y209-A320 HydrophobicContact CD1-CB 4.04Å; Y209-A320 HydrophobicContact CE1-CB 3.87Å; Y209-F323 AromaticContact CD1-CD2 3.57Å; Y209-F323 HydrophobicContact CD1-CD2 3.57Å; Y209-F323 AromaticContact CD1-CE2 3.98Å; Y209-F323 HydrophobicContact CD1-CE2 3.98Å; Y209-F323 HydrophobicContact CD2-CE2 4.49Å; Y209-F323 HydrophobicContact CE1-CD2 4.13Å; Y209-F323 HydrophobicContact CE1-CE2 4.39Å; Y209-F323 AromaticContact CG-CD2 3.98Å; Y209-F323 HydrophobicContact CG-CD2 3.98Å; Y209-F323 HydrophobicContact CG-CE2 4.03Å
210	V	94.3	Very high	90.1	Very high	0 Å²	0	50.4 Å²	50.4	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-55.4	-47.4	175.4	172.9	0	0	0	0	110.9	L64 L65 G206 T207 W208 I212 V213 V214 L307 A320 I324	L64-V210 HydrophobicContact CD2-CB 4.38Å; L64-V210 HydrophobicContact CD2-CG1 4.14Å; L65-V210 HydrophobicContact CD2-CG1 4.25Å; G206-V210 VanDerWaalsContact O-CG2 3.25Å; G206-V210 WeakPolarHBondContact O-CG2 3.41Å; G206-V210 PolarHBondContact O-N 3.2Å; T207-V210 PolarHBondContact O-N 3.44Å; W208-V210 PolarHBondContact O-N 3.06Å; V210-I212 PolarHBondContact O-N 3.42Å; V210-V213 PolarHBondContact O-N 3.4Å; V210-V214 WeakPolarHBondContact O-CG2 3.2Å; V210-V214 PolarHBondContact O-N 3.28Å; V210-L307 HydrophobicContact CG1-CD1 4.41Å; V210-L307 HydrophobicContact CG1-CD2 4.43Å; V210-A320 HydrophobicContact CG2-CB 3.89Å; V210-I324 HydrophobicContact CG2-CD1 3.77Å; V210-I324 HydrophobicContact CG2-CG1 3.69Å
211	T	95.2	Very high	90.3	Very high	2 Å²	2	53.4 Å²	53.4	1%	0.012	26%	0.258	C	S	.	.	H	α-helix	trans	-60.1	-45.6	178.2	-55.4	0	0	0	0	111.7	T207 W208 Y209 V214 I215 V286 T290	T207-T211 PolarHBondContact O-N 2.86Å; T207-T211 PolarHBondContact O-OG1 3.49Å; W208-T211 WeakPolarHBondContact O-CB 3.23Å; W208-T211 PolarHBondContact O-N 2.93Å; Y209-T211 VanDerWaalsContact C-N 3.31Å; Y209-T211 PolarHBondContact O-N 3.45Å; T211-V214 PolarHBondContact O-N 3.18Å; T211-I215 HydrophobicContact CG2-CD1 3.87Å; T211-I215 VanDerWaalsContact O-CG1 3.28Å; T211-I215 WeakPolarHBondContact O-CG1 2.93Å; T211-I215 PolarHBondContact O-N 2.89Å; T211-V286 WeakPolarHBondContact OG1-CG1 3.42Å; T211-T290 WeakPolarHBondContact CG2-OG1 3.45Å; T211-T290 PolarHBondContact OG1-OG1 2.84Å
212	I	95.8	Very high	89.8	Confident	90 Å²	90	54.5 Å²	54.5	46%	0.462	26%	0.259	S	S	.	.	H	α-helix	trans	-62.7	-43.9	178.9	-68.8	163.5	0	0	0	110.4	W208 Y209 V210 V214 I215 V216	W208-I212 VanDerWaalsContact O-CG1 3.25Å; W208-I212 WeakPolarHBondContact O-CG1 3.14Å; W208-I212 PolarHBondContact O-N 3.09Å; Y209-I212 PolarHBondContact O-N 2.97Å; V210-I212 PolarHBondContact O-N 3.42Å; I212-V214 PolarHBondContact O-N 3.1Å; I212-I215 PolarHBondContact O-N 3.46Å; I212-V216 HydrophobicContact CG2-CG2 4.17Å; I212-V216 WeakPolarHBondContact O-CB 3.36Å; I212-V216 VanDerWaalsContact O-CG2 3.28Å; I212-V216 WeakPolarHBondContact O-CG2 3.13Å; I212-V216 PolarHBondContact O-N 2.95Å
213	V	94.9	Very high	88.9	Confident	10 Å²	10	60.6 Å²	60.6	6%	0.061	28%	0.282	C	S	.	.	H	α-helix	trans	-59.7	-46.5	176.9	170	0	0	0	0	110.8	Y209 V210 I215 V216 K217 A316 V317 A320	Y209-V213 HydrophobicContact CD1-CG2 4.06Å; Y209-V213 HydrophobicContact CE1-CG2 3.58Å; Y209-V213 HydrophobicContact CE2-CG2 4.19Å; Y209-V213 WeakPolarHBondContact O-CG2 3.46Å; Y209-V213 PolarHBondContact O-N 3.22Å; V210-V213 PolarHBondContact O-N 3.4Å; V213-I215 VanDerWaalsContact C-N 3.35Å; V213-I215 PolarHBondContact O-N 2.71Å; V213-V216 PolarHBondContact O-N 2.84Å; V213-K217 HydrophobicContact CG1-CG 4.36Å; V213-K217 WeakPolarHBondContact O-CB 3.37Å; V213-K217 VanDerWaalsContact O-CG 3.31Å; V213-K217 WeakPolarHBondContact O-CG 3.25Å; V213-K217 PolarHBondContact O-N 3.07Å; V213-A316 HydrophobicContact CG1-CB 4.44Å; V213-A316 HydrophobicContact CG2-CB 4.34Å; V213-V317 HydrophobicContact CG1-CG2 3.98Å; V213-A320 HydrophobicContact CG2-CB 4.49Å
214	V	94.1	Very high	87.9	Confident	0 Å²	0	67.8 Å²	67.8	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-61.3	-42.3	177.7	172.5	0	0	0	0	111.6	V210 T211 I212 Y218 T290 C293 Y310	V210-V214 WeakPolarHBondContact O-CG2 3.2Å; V210-V214 PolarHBondContact O-N 3.28Å; T211-V214 PolarHBondContact O-N 3.18Å; I212-V214 PolarHBondContact O-N 3.1Å; V214-Y218 PolarHBondContact O-N 3.21Å; V214-Y218 VanDerWaalsContact O-N 3.12Å; V214-T290 HydrophobicContact CG1-CG2 4.43Å; V214-T290 HydrophobicContact CG2-CG2 4.4Å; V214-C293 HydrophobicContact CG1-CB 4.01Å; V214-Y310 HydrophobicContact CG2-CE2 4.27Å
215	I	94.6	Very high	86.7	Confident	56 Å²	56	68.2 Å²	68.2	29%	0.287	32%	0.322	S	S	.	.	H	α-helix	trans	-65	-46.8	176.5	-68	167.5	0	0	0	111.1	T211 I212 V213 K217 Y218 I219 C293	T211-I215 HydrophobicContact CG2-CD1 3.87Å; T211-I215 VanDerWaalsContact O-CG1 3.28Å; T211-I215 WeakPolarHBondContact O-CG1 2.93Å; T211-I215 PolarHBondContact O-N 2.89Å; I212-I215 PolarHBondContact O-N 3.46Å; V213-I215 VanDerWaalsContact C-N 3.35Å; V213-I215 PolarHBondContact O-N 2.71Å; I215-K217 VanDerWaalsContact C-N 3.33Å; I215-K217 PolarHBondContact O-N 3.44Å; I215-Y218 WeakPolarHBondContact O-CB 3.15Å; I215-Y218 PolarHBondContact O-N 2.98Å; I215-I219 HydrophobicContact CG2-CD1 3.83Å; I215-I219 WeakPolarHBondContact O-CG1 3.23Å; I215-I219 PolarHBondContact O-N 3.42Å; I215-I219 VanDerWaalsContact O-N 3.08Å; I215-C293 HydrophobicContact CG1-CB 4.25Å
216	V	93.6	Very high	85.2	Confident	74 Å²	74	68.7 Å²	68.7	45%	0.448	33%	0.327	S	S	.	.	H	α-helix	trans	-61.7	-43.6	-179.7	168.1	0	0	0	0	110.5	I212 V213 Y218 I219 W220	I212-V216 HydrophobicContact CG2-CG2 4.17Å; I212-V216 WeakPolarHBondContact O-CB 3.36Å; I212-V216 VanDerWaalsContact O-CG2 3.28Å; I212-V216 WeakPolarHBondContact O-CG2 3.13Å; I212-V216 PolarHBondContact O-N 2.95Å; V213-V216 PolarHBondContact O-N 2.84Å; V216-Y218 VanDerWaalsContact C-N 3.27Å; V216-Y218 PolarHBondContact O-N 2.98Å; V216-I219 PolarHBondContact O-N 3.2Å; V216-W220 PolarHBondContact O-N 2.93Å
217	K	90.2	Very high	83.7	Confident	20 Å²	20	71.4 Å²	71.4	9%	0.087	35%	0.345	C	S	.	.	H	α-helix	trans	-66.7	-27.4	178.1	-72.6	-75.2	160.1	172.4	0	113.7	V213 I215 W220 P221 D222 Y310 D314	V213-K217 HydrophobicContact CG1-CG 4.36Å; V213-K217 WeakPolarHBondContact O-CB 3.37Å; V213-K217 VanDerWaalsContact O-CG 3.31Å; V213-K217 WeakPolarHBondContact O-CG 3.25Å; V213-K217 PolarHBondContact O-N 3.07Å; I215-K217 VanDerWaalsContact C-N 3.33Å; I215-K217 PolarHBondContact O-N 3.44Å; K217-W220 CarbonylContact O-C 3.48Å; K217-P221 VanDerWaalsContact O-CA 3.22Å; K217-P221 WeakPolarHBondContact O-CA 3.49Å; K217-D222 IonicContact NZ-OD1 2.88Å; K217-D222 PolarHBondContact NZ-OD1 3.44Å; K217-D222 IonicContact NZ-OD2 2.61Å; K217-D222 PolarHBondContact NZ-OD2 2.95Å; K217-Y310 HydrophobicContact CB-CE1 3.61Å; K217-Y310 HydrophobicContact CD-CE1 4.35Å; K217-Y310 HydrophobicContact CG-CD1 4.45Å; K217-Y310 HydrophobicContact CG-CE1 3.81Å; K217-D314 WeakPolarHBondContact CE-OD2 3.36Å; K217-D314 IonicContact NZ-OD1 3.88Å; K217-D314 IonicContact NZ-OD2 2.61Å; K217-D314 PolarHBondContact NZ-OD2 3.34Å
218	Y	89.9	Confident	82	Confident	93 Å²	93	76.1 Å²	76.1	37%	0.365	37%	0.37	S	S	.	.	H	α-helix	trans	-71.6	-41.5	171.2	170.8	-108.6	0	0	0	112.2	V214 I215 V216 C293 L296	V214-Y218 PolarHBondContact O-N 3.21Å; V214-Y218 VanDerWaalsContact O-N 3.12Å; I215-Y218 WeakPolarHBondContact O-CB 3.15Å; I215-Y218 PolarHBondContact O-N 2.98Å; V216-Y218 VanDerWaalsContact C-N 3.27Å; V216-Y218 PolarHBondContact O-N 2.98Å; Y218-C293 HydrophobicContact CD1-CB 4.22Å; Y218-C293 HydrophobicContact CG-CB 4.02Å; Y218-L296 HydrophobicContact CD2-CB 3.87Å; Y218-L296 HydrophobicContact CE1-CD1 4.35Å; Y218-L296 HydrophobicContact CE2-CB 3.36Å; Y218-L296 HydrophobicContact CE2-CD1 4.06Å; Y218-L296 HydrophobicContact CE2-CG 4.35Å
219	I	89.9	Confident	80.2	Confident	100 Å²	100	79.4 Å²	79.4	51%	0.513	39%	0.389	S	S	.	.	H	α-helix	trans	-76.5	-40.1	-178.1	-60.1	170	0	0	0	111.4	I215 V216 P221	I215-I219 HydrophobicContact CG2-CD1 3.83Å; I215-I219 WeakPolarHBondContact O-CG1 3.23Å; I215-I219 PolarHBondContact O-N 3.42Å; I215-I219 VanDerWaalsContact O-N 3.08Å; V216-I219 PolarHBondContact O-N 3.2Å; I219-P221 VanDerWaalsContact C-CD 3.48Å; I219-P221 WeakPolarHBondContact O-CD 3.32Å
220	W	87.6	Confident	78.1	Confident	200 Å²	200	77.4 Å²	77.4	76%	0.758	39%	0.386	S	S	*	.	S	Bend	trans	-119.7	79.1	175.7	-95.3	-83.2	0	0	0	109.7	V216 K217	V216-W220 PolarHBondContact O-N 2.93Å; K217-W220 CarbonylContact O-C 3.48Å
221	P	80.5	Confident	76.2	Confident	64 Å²	64	82.9 Å²	82.9	42%	0.416	42%	0.421	S	S	.	.			trans	-66.7	142.9	176.4	25.8	-31.8	0	0	0	110.9	K217 I219 M225	K217-P221 VanDerWaalsContact O-CA 3.22Å; K217-P221 WeakPolarHBondContact O-CA 3.49Å; I219-P221 VanDerWaalsContact C-CD 3.48Å; I219-P221 WeakPolarHBondContact O-CD 3.32Å; P221-M225 HydrophobicContact CB-CB 4.26Å
222	D	73.1	Confident	74.4	Confident	58 Å²	58	85.5 Å²	85.5	31%	0.31	44%	0.443	S	S	.	.			trans	-68.6	158.2	170.9	-59.4	-39.7	0	0	0	110	K217 D224 M225	K217-D222 IonicContact NZ-OD1 2.88Å; K217-D222 PolarHBondContact NZ-OD1 3.44Å; K217-D222 IonicContact NZ-OD2 2.61Å; K217-D222 PolarHBondContact NZ-OD2 2.95Å; D222-D224 PolarHBondContact O-N 2.7Å; D222-M225 HydrophobicContact CB-CG 4.34Å; D222-M225 PolarHBondContact O-N 3.27Å
223	K	64.2	Low	72.7	Confident	202 Å²	202	85.2 Å²	85.2	88%	0.878	45%	0.446	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.7	-22.8	-174.6	-70.1	178.7	-179.9	171.9	0	114.2
224	D	62.7	Low	71.2	Confident	152 Å²	152	90 Å²	90	81%	0.813	48%	0.479	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.5	-5.9	-179	-53.9	-46.8	0	0	0	112.9	D222	D222-D224 PolarHBondContact O-N 2.7Å
225	M	61.8	Low	70.1	Confident	20 Å²	20	93.1 Å²	93.1	10%	0.099	51%	0.506	C	S	.	.			trans	-100	82.5	177	-63.3	-173.1	77.3	0	0	109.7	P221 D222 P227 T297 F298 Y310	P221-M225 HydrophobicContact CB-CB 4.26Å; D222-M225 HydrophobicContact CB-CG 4.34Å; D222-M225 PolarHBondContact O-N 3.27Å; M225-P227 WeakPolarHBondContact O-CD 3.35Å; M225-T297 HydrophobicContact CE-CG2 3.38Å; M225-F298 HydrophobicContact CE-CE1 3.48Å; M225-F298 VanDerWaalsContact CE-CE1 3.48Å; M225-F298 HydrophobicContact CE-CE2 4.39Å; M225-F298 HydrophobicContact CE-CZ 3.39Å; M225-Y310 HydrophobicContact CE-CD1 3.62Å; M225-Y310 HydrophobicContact CE-CE1 3.41Å; M225-Y310 VanDerWaalsContact CE-CE1 3.41Å; M225-Y310 HydrophobicContact SD-CD1 3.94Å; M225-Y310 HydrophobicContact SD-CE1 3.99Å
226	N	58.3	Low	69.6	Low	137 Å²	137	92.7 Å²	92.7	73%	0.733	51%	0.507	S	S	*	.			trans	-76.5	121.6	166.5	-77.5	-27.9	0	0	0	108.4	D228	N226-D228 VanDerWaalsContact C-N 3.28Å; N226-D228 PolarHBondContact O-N 2.95Å
227	P	57.6	Low	69	Low	56 Å²	56	99 Å²	99	36%	0.364	52%	0.524	S	S	.	.			trans	-63.5	97.6	170.4	24.6	-30.2	0	0	0	107.4	M225 H229	M225-P227 WeakPolarHBondContact O-CD 3.35Å; P227-H229 PolarHBondContact O-N 3.2Å; P227-H229 VanDerWaalsContact O-N 3.07Å; P227-H229 PolarHBondContact O-ND1 3.42Å
228	D	54.8	Low	68.7	Low	100 Å²	100	102.6 Å²	102.6	54%	0.535	55%	0.547	S	S	.	.			trans	-65.2	116	177	-144.3	5	0	0	0	105.5	N226 A230	N226-D228 VanDerWaalsContact C-N 3.28Å; N226-D228 PolarHBondContact O-N 2.95Å; D228-A230 PolarHBondContact O-N 3.17Å
229	H	55.8	Low	68.5	Low	170 Å²	170	99 Å²	99	79%	0.787	54%	0.536	S	S	*	.			trans	-75.3	51.1	175	-69.1	59.5	0	0	0	108.4	P227 P231	P227-H229 PolarHBondContact O-N 3.2Å; P227-H229 VanDerWaalsContact O-N 3.07Å; P227-H229 PolarHBondContact O-ND1 3.42Å; H229-P231 WeakPolarHBondContact O-CD 3.37Å
230	A	52.1	Low	68.4	Low	21 Å²	21	95.3 Å²	95.3	17%	0.174	52%	0.518	C	S	.	.	P	Polyproline II helix	trans	-56.1	117.2	172.9	0	0	0	0	0	106	D228 A232 S300	D228-A230 PolarHBondContact O-N 3.17Å; A230-A232 PolarHBondContact O-N 3.22Å; A230-A232 VanDerWaalsContact O-N 3.15Å; A230-S300 WeakPolarHBondContact CB-OG 3.39Å
231	P	54	Low	68.4	Low	115 Å²	115	88 Å²	88	75%	0.747	49%	0.492	S	S	*	.	P	Polyproline II helix	trans	-57.7	128.4	-176.3	21.4	-30.4	0	0	0	107.4	H229 T233	H229-P231 WeakPolarHBondContact O-CD 3.37Å; P231-T233 PolarHBondContact O-N 3.46Å
232	A	57.4	Low	68.6	Low	57 Å²	57	87.9 Å²	87.9	47%	0.471	49%	0.488	S	S	.	.	P	Polyproline II helix	trans	-50.3	120.2	172	0	0	0	0	0	107.5	A230 S234	A230-A232 PolarHBondContact O-N 3.22Å; A230-A232 VanDerWaalsContact O-N 3.15Å; A232-S234 PolarHBondContact O-N 3.26Å
233	T	59.7	Low	69.4	Low	85 Å²	85	85.1 Å²	85.1	52%	0.521	47%	0.473	S	S	.	.	P	Polyproline II helix	trans	-51.1	130.7	170.6	32	0	0	0	0	107.4	G75 P231 A235	G75-T233 VanDerWaalsContact CA-O 3.22Å; G75-T233 WeakPolarHBondContact CA-O 3.43Å; P231-T233 PolarHBondContact O-N 3.46Å; T233-A235 PolarHBondContact O-N 3.49Å; T233-A235 VanDerWaalsContact O-N 3.07Å
234	S	64	Low	70.7	Confident	109 Å²	109	75.8 Å²	75.8	76%	0.762	43%	0.433	S	S	*	.	P	Polyproline II helix	trans	-51.4	122.4	-174.5	47.4	0	0	0	0	109.9	A232 S236	A232-S234 PolarHBondContact O-N 3.26Å; S234-S236 PolarHBondContact O-N 2.98Å
235	A	70.4	Confident	72	Confident	67 Å²	67	68.8 Å²	68.8	55%	0.554	40%	0.395	S	S	*	.			trans	-57.6	111.4	-179.6	0	0	0	0	0	108.8	A79 T233	A79-A235 HydrophobicContact CB-CB 4.25Å; T233-A235 PolarHBondContact O-N 3.49Å; T233-A235 VanDerWaalsContact O-N 3.07Å
236	S	83.9	Confident	73.4	Confident	46 Å²	46	68.1 Å²	68.1	32%	0.322	39%	0.393	S	S	.	.			trans	-109.8	151.1	173.3	63.9	0	0	0	0	108.9	S234 T238 A239 V240	S234-S236 PolarHBondContact O-N 2.98Å; S236-T238 PolarHBondContact O-N 2.93Å; S236-T238 PolarHBondContact OG-OG1 3.25Å; S236-A239 WeakPolarHBondContact O-CB 3.28Å; S236-A239 PolarHBondContact O-N 3.44Å; S236-A239 VanDerWaalsContact OG-CB 3.23Å; S236-A239 WeakPolarHBondContact OG-CB 3.44Å; S236-A239 PolarHBondContact OG-N 3.44Å; S236-V240 PolarHBondContact O-N 3.02Å; S236-V240 VanDerWaalsContact O-N 3.07Å
237	W	81.8	Confident	75	Confident	208 Å²	208	61.7 Å²	61.7	79%	0.788	36%	0.358	S	S	*	.	H	α-helix	trans	-55	-38.2	176.5	-69.3	106.3	0	0	0	111.9	V240 F241	W237-V240 PolarHBondContact O-N 3.43Å; W237-F241 HydrophobicContact CB-CE2 4.26Å; W237-F241 WeakPolarHBondContact O-CD2 3.45Å; W237-F241 WeakPolarHBondContact O-CG 3.3Å; W237-F241 PolarHBondContact O-N 3.31Å
238	T	83.6	Confident	76.7	Confident	94 Å²	94	59.1 Å²	59.1	58%	0.577	34%	0.341	S	S	*	.	H	α-helix	trans	-61.4	-42	174.1	38.6	0	0	0	0	113.2	S236 F241 N242	S236-T238 PolarHBondContact O-N 2.93Å; S236-T238 PolarHBondContact OG-OG1 3.25Å; T238-F241 PolarHBondContact O-N 3.5Å; T238-N242 VanDerWaalsContact O-CG 3.27Å; T238-N242 PolarHBondContact O-N 3.29Å; T238-N242 PolarHBondContact O-ND2 3.47Å
239	A	85.1	Confident	78.5	Confident	17 Å²	17	54.9 Å²	54.9	14%	0.14	32%	0.318	C	S	.	.	H	α-helix	trans	-64.3	-45.3	178	0	0	0	0	0	111.5	M73 S236 F241 N242 A243	M73-A239 CarbonylContact O-C 3.56Å; M73-A239 VanDerWaalsContact O-CB 3.28Å; M73-A239 WeakPolarHBondContact O-CB 3.45Å; S236-A239 WeakPolarHBondContact O-CB 3.28Å; S236-A239 PolarHBondContact O-N 3.44Å; S236-A239 VanDerWaalsContact OG-CB 3.23Å; S236-A239 WeakPolarHBondContact OG-CB 3.44Å; S236-A239 PolarHBondContact OG-N 3.44Å; A239-F241 PolarHBondContact O-N 3.22Å; A239-N242 PolarHBondContact O-N 3.43Å; A239-A243 PolarHBondContact O-N 2.98Å
240	V	88.3	Confident	80.2	Confident	23 Å²	23	46.8 Å²	46.8	14%	0.139	28%	0.281	C	S	.	.	H	α-helix	trans	-59.2	-45	175.7	176.6	0	0	0	0	111.3	A79 L83 S236 W237 N242 A243 M244	A79-V240 HydrophobicContact CB-CG2 4.36Å; L83-V240 HydrophobicContact CB-CG1 4.39Å; L83-V240 HydrophobicContact CD1-CG1 4.06Å; L83-V240 HydrophobicContact CD2-CG1 3.96Å; L83-V240 WeakPolarHBondContact CD2-O 3.4Å; L83-V240 HydrophobicContact CG-CG1 4.36Å; S236-V240 PolarHBondContact O-N 3.02Å; S236-V240 VanDerWaalsContact O-N 3.07Å; W237-V240 PolarHBondContact O-N 3.43Å; V240-N242 VanDerWaalsContact C-N 3.34Å; V240-N242 PolarHBondContact O-N 3.13Å; V240-A243 PolarHBondContact O-N 3.35Å; V240-M244 HydrophobicContact CG1-CE 4.35Å; V240-M244 PolarHBondContact O-N 3.47Å
241	F	87	Confident	82.2	Confident	48 Å²	48	45.8 Å²	45.8	21%	0.211	27%	0.273	C	S	.	.	H	α-helix	trans	-67.3	-32.5	178.9	-69.3	-55.4	0	0	0	113.4	W237 T238 A239 A243 M244 P245 F441 L445	W237-F241 HydrophobicContact CB-CE2 4.26Å; W237-F241 WeakPolarHBondContact O-CD2 3.45Å; W237-F241 WeakPolarHBondContact O-CG 3.3Å; W237-F241 PolarHBondContact O-N 3.31Å; T238-F241 PolarHBondContact O-N 3.5Å; A239-F241 PolarHBondContact O-N 3.22Å; F241-A243 VanDerWaalsContact C-N 3.28Å; F241-A243 PolarHBondContact O-N 2.84Å; F241-M244 HydrophobicContact CD1-CE 3.37Å; F241-M244 HydrophobicContact CD1-SD 3.66Å; F241-M244 HydrophobicContact CE1-CE 3.56Å; F241-M244 HydrophobicContact CE1-SD 4.24Å; F241-M244 WeakPolarHBondContact O-CB 3.41Å; F241-M244 PolarHBondContact O-N 3.44Å; F241-P245 WeakPolarHBondContact O-CD 3.21Å; F241-F441 AromaticContact CD1-CE1 3.75Å; F241-F441 HydrophobicContact CD1-CE1 3.75Å; F241-F441 HydrophobicContact CD2-CE1 4.13Å; F241-F441 HydrophobicContact CD2-CZ 4.36Å; F241-F441 HydrophobicContact CE1-CD1 4.33Å; F241-F441 AromaticContact CE1-CE1 3.64Å; F241-F441 HydrophobicContact CE1-CE1 3.64Å; F241-F441 HydrophobicContact CE2-CE1 4.03Å; F241-F441 HydrophobicContact CE2-CZ 4.25Å; F241-F441 HydrophobicContact CG-CE1 4.04Å; F241-F441 AromaticContact CZ-CE1 3.8Å; F241-F441 HydrophobicContact CZ-CE1 3.8Å; F241-F441 HydrophobicContact CZ-CZ 4.38Å; F241-L445 HydrophobicContact CB-CD2 3.39Å; F241-L445 HydrophobicContact CD2-CD2 4.45Å; F241-L445 HydrophobicContact CG-CD2 4.01Å
242	N	85.4	Confident	84	Confident	60 Å²	60	40.8 Å²	40.8	32%	0.321	24%	0.239	S	C	.	.	H	α-helix	trans	-69.3	-24.6	175.6	-73.1	-23.3	0	0	0	113.3	T238 A239 V240 P245 N449	T238-N242 VanDerWaalsContact O-CG 3.27Å; T238-N242 PolarHBondContact O-N 3.29Å; T238-N242 PolarHBondContact O-ND2 3.47Å; A239-N242 PolarHBondContact O-N 3.43Å; V240-N242 VanDerWaalsContact C-N 3.34Å; V240-N242 PolarHBondContact O-N 3.13Å; N242-P245 WeakPolarHBondContact O-CD 3.36Å; N242-N449 PolarHBondContact OD1-ND2 3.26Å
243	A	90.4	Very high	85.7	Confident	0 Å²	0	38.2 Å²	38.2	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-81.1	-18.1	174.6	0	0	0	0	0	113.6	A70 M73 A74 L83 A239 V240 F241 T246 I247	A70-A243 VanDerWaalsContact O-CB 3.29Å; A70-A243 WeakPolarHBondContact O-CB 3.44Å; M73-A243 HydrophobicContact CB-CB 4.11Å; A74-A243 HydrophobicContact CB-CB 3.86Å; L83-A243 HydrophobicContact CD2-CB 4.14Å; A239-A243 PolarHBondContact O-N 2.98Å; V240-A243 PolarHBondContact O-N 3.35Å; F241-A243 VanDerWaalsContact C-N 3.28Å; F241-A243 PolarHBondContact O-N 2.84Å; A243-T246 PolarHBondContact O-N 2.73Å; A243-I247 PolarHBondContact O-N 2.88Å
244	M	90.8	Very high	87.3	Confident	7 Å²	7	34.1 Å²	34.1	3%	0.034	19%	0.193	C	C	.	.	H	α-helix	trans	-58.6	-43.4	-177.1	-71.8	-170.2	-177.1	0	0	114.4	L83 M87 V240 F241 T246 I247 C248 I442	L83-M244 HydrophobicContact CD1-CE 3.43Å; L83-M244 VanDerWaalsContact CD1-CE 3.43Å; L83-M244 HydrophobicContact CD1-CG 3.77Å; L83-M244 HydrophobicContact CD1-SD 4.28Å; L83-M244 HydrophobicContact CD2-CG 3.95Å; L83-M244 HydrophobicContact CG-CG 4.43Å; M87-M244 HydrophobicContact CE-CE 3.86Å; M87-M244 HydrophobicContact CE-SD 3.84Å; M87-M244 HydrophobicContact SD-CG 4.49Å; M87-M244 HydrophobicContact SD-SD 4.39Å; V240-M244 HydrophobicContact CG1-CE 4.35Å; V240-M244 PolarHBondContact O-N 3.47Å; F241-M244 HydrophobicContact CD1-CE 3.37Å; F241-M244 HydrophobicContact CD1-SD 3.66Å; F241-M244 HydrophobicContact CE1-CE 3.56Å; F241-M244 HydrophobicContact CE1-SD 4.24Å; F241-M244 WeakPolarHBondContact O-CB 3.41Å; F241-M244 PolarHBondContact O-N 3.44Å; M244-T246 VanDerWaalsContact C-N 3.3Å; M244-T246 PolarHBondContact O-N 3.41Å; M244-I247 PolarHBondContact O-N 3.24Å; M244-C248 WeakPolarHBondContact O-CB 3.49Å; M244-C248 PolarHBondContact O-N 3.19Å; M244-C248 PolarHBondContact O-SG 3.13Å; M244-I442 HydrophobicContact CB-CG2 4.22Å; M244-I442 HydrophobicContact SD-CD1 3.52Å; M244-I442 VanDerWaalsContact SD-CD1 3.52Å; M244-I442 HydrophobicContact SD-CG1 3.66Å
245	P	89.4	Confident	88.4	Confident	4 Å²	4	29.5 Å²	29.5	3%	0.026	16%	0.16	C	C	.	.	H	α-helix	trans	-54.3	-44.5	176.1	-31.4	38.3	0	0	0	113.6	F241 N242 I247 C248 F249 G395 T446	F241-P245 WeakPolarHBondContact O-CD 3.21Å; N242-P245 WeakPolarHBondContact O-CD 3.36Å; P245-I247 VanDerWaalsContact C-N 3.35Å; P245-C248 PolarHBondContact O-N 3.42Å; P245-F249 WeakPolarHBondContact O-CB 3.49Å; P245-F249 PolarHBondContact O-N 2.85Å; P245-G395 WeakPolarHBondContact O-CA 3.48Å; P245-T446 HydrophobicContact CB-CG2 4.46Å; P245-T446 HydrophobicContact CG-CG2 3.09Å
246	T	91.1	Very high	89.2	Confident	7 Å²	7	27.1 Å²	27.1	4%	0.043	14%	0.139	C	C	.	.	H	α-helix	trans	-65.3	-42	-178.3	-52.4	0	0	0	0	110.7	N66 A70 A243 M244 F249 G250 I391	N66-T246 HydrophobicContact CB-CG2 3.44Å; N66-T246 VanDerWaalsContact CB-CG2 3.44Å; A70-T246 HydrophobicContact CB-CG2 3.89Å; A243-T246 PolarHBondContact O-N 2.73Å; M244-T246 VanDerWaalsContact C-N 3.3Å; M244-T246 PolarHBondContact O-N 3.41Å; T246-F249 PolarHBondContact O-N 3.29Å; T246-G250 PolarHBondContact O-N 3.07Å; T246-I391 HydrophobicContact CG2-CG2 4.28Å
247	I	93.4	Very high	89.3	Confident	1 Å²	1	25 Å²	25	1%	0.005	13%	0.125	C	C	.	.	H	α-helix	trans	-66.6	-41.6	174.6	-63.8	177.8	0	0	0	110.8	F67 A70 L83 M87 A243 M244 P245 G250 F251	F67-I247 HydrophobicContact CE1-CG1 4.41Å; A70-I247 HydrophobicContact CB-CG1 4.26Å; L83-I247 HydrophobicContact CB-CD1 4.37Å; L83-I247 HydrophobicContact CD2-CD1 3.48Å; L83-I247 VanDerWaalsContact CD2-CD1 3.48Å; L83-I247 HydrophobicContact CG-CD1 3.68Å; M87-I247 HydrophobicContact CB-CG2 4.4Å; M87-I247 HydrophobicContact CG-CG2 4.37Å; A243-I247 PolarHBondContact O-N 2.88Å; M244-I247 PolarHBondContact O-N 3.24Å; P245-I247 VanDerWaalsContact C-N 3.35Å; I247-G250 PolarHBondContact O-N 2.93Å; I247-F251 HydrophobicContact CG2-CD2 3.8Å; I247-F251 HydrophobicContact CG2-CE2 4.13Å; I247-F251 WeakPolarHBondContact O-CD2 3.5Å; I247-F251 PolarHBondContact O-N 3.16Å
248	C	93.2	Very high	89.6	Confident	2 Å²	2	15.1 Å²	15.1	1%	0.014	9%	0.087	C	C	.	.	H	α-helix	trans	-61.5	-44.9	176.5	-70.6	0	0	0	0	111.3	M244 P245 F251 Q252 A398 I402	M244-C248 WeakPolarHBondContact O-CB 3.49Å; M244-C248 PolarHBondContact O-N 3.19Å; M244-C248 PolarHBondContact O-SG 3.13Å; P245-C248 PolarHBondContact O-N 3.42Å; C248-F251 PolarHBondContact O-N 3.1Å; C248-Q252 VanDerWaalsContact O-CB 3.31Å; C248-Q252 WeakPolarHBondContact O-CB 3.4Å; C248-Q252 PolarHBondContact O-N 3Å; C248-A398 HydrophobicContact CB-CB 3.96Å; C248-I402 HydrophobicContact CB-CD1 3.8Å; C248-I402 WeakPolarHBondContact O-CD1 3.43Å
249	F	91.6	Very high	89.6	Confident	11 Å²	11	12.9 Å²	12.9	5%	0.048	7%	0.074	C	C	.	.	H	α-helix	trans	-59.9	-47.8	174.4	174.3	-110.8	0	0	0	111.1	Y133 T137 P245 T246 F251 Q252 I391 I394	Y133-F249 HydrophobicContact CE2-CD2 4.29Å; T137-F249 HydrophobicContact CG2-CE2 3.88Å; T137-F249 HydrophobicContact CG2-CZ 4.23Å; P245-F249 WeakPolarHBondContact O-CB 3.49Å; P245-F249 PolarHBondContact O-N 2.85Å; T246-F249 PolarHBondContact O-N 3.29Å; F249-F251 PolarHBondContact O-N 3.24Å; F249-Q252 WeakPolarHBondContact O-CB 3.36Å; F249-Q252 PolarHBondContact O-N 2.91Å; F249-I391 HydrophobicContact CB-CG2 4.3Å; F249-I391 HydrophobicContact CD1-CD1 4.13Å; F249-I391 HydrophobicContact CD1-CG1 3.96Å; F249-I391 HydrophobicContact CD1-CG2 4.06Å; F249-I391 HydrophobicContact CE1-CD1 3.94Å; F249-I391 HydrophobicContact CE1-CG1 3.89Å; F249-I391 HydrophobicContact CG-CG2 4.31Å; F249-I391 HydrophobicContact CZ-CG1 4.44Å; F249-I394 HydrophobicContact CD2-CD1 3.57Å; F249-I394 HydrophobicContact CD2-CG1 3.74Å; F249-I394 HydrophobicContact CE2-CD1 3.28Å; F249-I394 HydrophobicContact CE2-CG1 4.01Å; F249-I394 HydrophobicContact CG-CD1 4.48Å; F249-I394 HydrophobicContact CG-CG1 4.47Å; F249-I394 HydrophobicContact CZ-CD1 4Å
250	G	92.4	Very high	89.7	Confident	0 Å²	0	12.7 Å²	12.7	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-62.5	-36.7	178.4	0	0	0	0	0	114.1	T246 I247 Y287	T246-G250 PolarHBondContact O-N 3.07Å; I247-G250 PolarHBondContact O-N 2.93Å; G250-Y287 PolarHBondContact O-OH 3.36Å
251	F	92.8	Very high	89.7	Confident	0 Å²	0	11.7 Å²	11.7	0%	0	7%	0.065	C	C	.	.	T	Hydrogen-bonded Turn	trans	-91.6	3.1	177.7	-82.7	-81.2	0	0	0	114.4	F67 Q84 L88 I91 I247 C248 F249 C253 M280 C283 Y287	F67-F251 HydrophobicContact CE1-CD2 4.35Å; F67-F251 AromaticContact CE1-CE2 3.83Å; F67-F251 HydrophobicContact CE1-CE2 3.83Å; F67-F251 AromaticContact CZ-CD2 3.84Å; F67-F251 HydrophobicContact CZ-CD2 3.84Å; F67-F251 AromaticContact CZ-CE2 3.69Å; F67-F251 HydrophobicContact CZ-CE2 3.69Å; Q84-F251 HydrophobicContact CG-CE2 3.77Å; Q84-F251 HydrophobicContact CG-CZ 4.02Å; Q84-F251 VanDerWaalsContact NE2-CZ 3.34Å; L88-F251 HydrophobicContact CD1-CD1 4.46Å; L88-F251 HydrophobicContact CD1-CE1 3.78Å; L88-F251 HydrophobicContact CD1-CZ 4.15Å; I91-F251 HydrophobicContact CD1-CB 3.4Å; I91-F251 VanDerWaalsContact CD1-CB 3.4Å; I91-F251 HydrophobicContact CD1-CD1 4.01Å; I91-F251 HydrophobicContact CD1-CD2 3.98Å; I91-F251 HydrophobicContact CD1-CG 3.56Å; I91-F251 HydrophobicContact CG1-CB 4.21Å; I247-F251 HydrophobicContact CG2-CD2 3.8Å; I247-F251 HydrophobicContact CG2-CE2 4.13Å; I247-F251 WeakPolarHBondContact O-CD2 3.5Å; I247-F251 PolarHBondContact O-N 3.16Å; C248-F251 PolarHBondContact O-N 3.1Å; F249-F251 PolarHBondContact O-N 3.24Å; F251-C253 PolarHBondContact O-N 3.36Å; F251-M280 HydrophobicContact CD1-SD 4.14Å; F251-C283 HydrophobicContact CD1-CB 4.48Å; F251-C283 HydrophobicContact CE1-CB 3.96Å; F251-Y287 HydrophobicContact CD1-CD2 4.18Å; F251-Y287 AromaticContact CD1-CE2 3.81Å; F251-Y287 HydrophobicContact CD1-CE2 3.81Å; F251-Y287 HydrophobicContact CD2-CD2 4.08Å; F251-Y287 HydrophobicContact CD2-CE2 4.01Å; F251-Y287 AromaticContact CE1-CD2 3.62Å; F251-Y287 HydrophobicContact CE1-CD2 3.62Å; F251-Y287 AromaticContact CE1-CE2 3.71Å; F251-Y287 HydrophobicContact CE1-CE2 3.71Å; F251-Y287 AromaticContact CE2-CD2 3.5Å; F251-Y287 HydrophobicContact CE2-CD2 3.5Å; F251-Y287 VanDerWaalsContact CE2-CD2 3.5Å; F251-Y287 AromaticContact CE2-CE2 3.9Å; F251-Y287 HydrophobicContact CE2-CE2 3.9Å; F251-Y287 HydrophobicContact CE2-CG 4.45Å; F251-Y287 HydrophobicContact CG-CD2 4.42Å; F251-Y287 AromaticContact CG-CE2 3.99Å; F251-Y287 HydrophobicContact CG-CE2 3.99Å; F251-Y287 AromaticContact CZ-CD2 3.3Å; F251-Y287 HydrophobicContact CZ-CD2 3.3Å; F251-Y287 AromaticContact CZ-CE2 3.81Å; F251-Y287 HydrophobicContact CZ-CE2 3.81Å; F251-Y287 HydrophobicContact CZ-CG 4.4Å
252	Q	92.6	Very high	89.6	Confident	10 Å²	10	10.9 Å²	10.9	5%	0.047	6%	0.063	C	C	.	.			trans	-70.7	103.7	-174.7	-176.7	57	-95.4	0	0	111.3	Y133 C248 F249 H254 A398	Y133-Q252 HydrophobicContact CE1-CG 3.94Å; Y133-Q252 HydrophobicContact CE2-CG 4.19Å; Y133-Q252 VanDerWaalsContact OH-CB 3.31Å; Y133-Q252 WeakPolarHBondContact OH-CB 3.12Å; Y133-Q252 WeakPolarHBondContact OH-CG 3.29Å; C248-Q252 VanDerWaalsContact O-CB 3.31Å; C248-Q252 WeakPolarHBondContact O-CB 3.4Å; C248-Q252 PolarHBondContact O-N 3Å; F249-Q252 WeakPolarHBondContact O-CB 3.36Å; F249-Q252 PolarHBondContact O-N 2.91Å; Q252-H254 VanDerWaalsContact OE1-CB 3.26Å; Q252-H254 PolarHBondContact OE1-ND1 3.39Å; Q252-A398 HydrophobicContact CB-CB 4.15Å; Q252-A398 HydrophobicContact CG-CB 4.22Å; Q252-A398 PolarHBondContact NE2-O 3.23Å
253	C	92.5	Very high	89.5	Confident	3 Å²	3	10.1 Å²	10.1	2%	0.02	6%	0.062	C	C	.	.			trans	-130	0.4	171	59.1	0	0	0	0	112.5	A58 A59 F251 V255 S256 C257 M280	A58-C253 HydrophobicContact CB-CB 3.88Å; A59-C253 HydrophobicContact CB-CB 4.27Å; F251-C253 PolarHBondContact O-N 3.36Å; C253-V255 PolarHBondContact O-N 3.43Å; C253-S256 PolarHBondContact O-N 3Å; C253-C257 PolarHBondContact O-N 3.3Å; C253-C257 VanDerWaalsContact O-N 3.13Å; C253-M280 WeakPolarHBondContact SG-CE 3.31Å
254	H	93.3	Very high	89.3	Confident	0 Å²	0	10.5 Å²	10.5	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-65.1	-39	-173	-60.2	58.7	0	0	0	112	I91 L95 L98 Y110 Q252 S256 C257 F401	I91-H254 PolarHBondContact O-NE2 3.46Å; L95-H254 HydrophobicContact CD2-CB 4.22Å; L98-H254 HydrophobicContact CD1-CB 3.96Å; Y110-H254 WeakPolarHBondContact CD2-O 3.33Å; Y110-H254 HydrophobicContact CE2-CB 3.95Å; Q252-H254 VanDerWaalsContact OE1-CB 3.26Å; Q252-H254 PolarHBondContact OE1-ND1 3.39Å; H254-S256 PolarHBondContact O-N 3.25Å; H254-S256 VanDerWaalsContact O-N 3.16Å; H254-C257 WeakPolarHBondContact O-CB 3.35Å; H254-C257 PolarHBondContact O-N 3.36Å; H254-C257 PolarHBondContact O-SG 2.78Å; H254-F401 HydrophobicContact CB-CB 4.37Å
255	V	88.6	Confident	89	Confident	11 Å²	11	16.5 Å²	16.5	7%	0.067	9%	0.09	C	C	.	.	H	α-helix	trans	-55.3	-36.7	177.4	177.9	0	0	0	0	111.6	I130 Y133 C253 C338 F401	I130-V255 HydrophobicContact CD1-CG1 4.5Å; I130-V255 HydrophobicContact CG1-CG1 4.38Å; I130-V255 HydrophobicContact CG1-CG2 4.36Å; I130-V255 HydrophobicContact CG2-CG1 3.84Å; Y133-V255 HydrophobicContact CD1-CG2 4.36Å; C253-V255 PolarHBondContact O-N 3.43Å; V255-C338 HydrophobicContact CG1-CB 4.43Å; V255-F401 HydrophobicContact CG2-CB 4.44Å; V255-F401 HydrophobicContact CG2-CD1 4.36Å; V255-F401 HydrophobicContact CG2-CD2 3.8Å; V255-F401 HydrophobicContact CG2-CE2 4.16Å; V255-F401 HydrophobicContact CG2-CG 3.95Å
256	S	85.3	Confident	88.9	Confident	18 Å²	18	25.1 Å²	25.1	13%	0.126	12%	0.122	C	C	.	.	H	α-helix	trans	-91.6	-9.3	-179.7	-57.1	0	0	0	0	113.3	C253 H254 P259 V260	C253-S256 PolarHBondContact O-N 3Å; H254-S256 PolarHBondContact O-N 3.25Å; H254-S256 VanDerWaalsContact O-N 3.16Å; S256-P259 WeakPolarHBondContact O-CD 3.5Å; S256-V260 WeakPolarHBondContact O-CG2 3.17Å; S256-V260 PolarHBondContact O-N 2.81Å
257	C	87.3	Confident	88.6	Confident	2 Å²	2	30.4 Å²	30.4	1%	0.014	14%	0.144	C	C	.	.	H	α-helix	trans	-72.3	-36.9	-168.1	84.3	0	0	0	0	113.3	L95 C253 H254 V260 F261 W272	L95-C257 HydrophobicContact CD2-CB 3.46Å; L95-C257 VanDerWaalsContact CD2-CB 3.46Å; C253-C257 PolarHBondContact O-N 3.3Å; C253-C257 VanDerWaalsContact O-N 3.13Å; H254-C257 WeakPolarHBondContact O-CB 3.35Å; H254-C257 PolarHBondContact O-N 3.36Å; H254-C257 PolarHBondContact O-SG 2.78Å; C257-V260 PolarHBondContact O-N 3.3Å; C257-F261 WeakPolarHBondContact O-CB 3.31Å; C257-F261 PolarHBondContact O-N 2.91Å; C257-W272 HydrophobicContact CB-CH2 4.01Å; C257-W272 HydrophobicContact CB-CZ2 3.84Å; C257-W272 VanDerWaalsContact O-CH2 3.24Å; C257-W272 WeakPolarHBondContact O-CH2 3.41Å
258	V	88.6	Confident	88.6	Confident	0 Å²	0	31.4 Å²	31.4	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-67.3	-47	-179.4	176.3	0	0	0	0	111.9	L98 Y110 V113 V260 F261 N262	L98-V258 HydrophobicContact CB-CG2 4.13Å; Y110-V258 HydrophobicContact CD2-CG2 4.46Å; V113-V258 HydrophobicContact CG2-CG1 3.83Å; V113-V258 HydrophobicContact CG2-CG2 4.38Å; V258-V260 VanDerWaalsContact C-N 3.29Å; V258-V260 PolarHBondContact O-N 3.19Å; V258-F261 PolarHBondContact O-N 3.25Å; V258-N262 PolarHBondContact O-N 2.93Å; V258-N262 PolarHBondContact O-ND2 3.22Å
259	P	83.6	Confident	88.6	Confident	47 Å²	47	33.3 Å²	33.3	31%	0.305	16%	0.162	S	C	.	.	H	α-helix	trans	-57.1	-40.6	170	-27.5	34.9	0	0	0	113.2	S256 N262 S263	S256-P259 WeakPolarHBondContact O-CD 3.5Å; P259-N262 PolarHBondContact O-N 3.29Å; P259-S263 WeakPolarHBondContact O-CB 3.31Å; P259-S263 PolarHBondContact O-N 3.26Å
260	V	85.8	Confident	88.7	Confident	13 Å²	13	42 Å²	42	8%	0.079	20%	0.2	C	C	.	.	H	α-helix	trans	-65.5	-45.5	178.9	176.3	0	0	0	0	111.3	A51 I54 V55 S256 C257 V258 N262 S263 M264 W272	A51-V260 HydrophobicContact CB-CG1 4.13Å; I54-V260 HydrophobicContact CG2-CG1 4.38Å; I54-V260 HydrophobicContact CG2-CG2 3.55Å; V55-V260 HydrophobicContact CG2-CG1 3.98Å; S256-V260 WeakPolarHBondContact O-CG2 3.17Å; S256-V260 PolarHBondContact O-N 2.81Å; C257-V260 PolarHBondContact O-N 3.3Å; V258-V260 VanDerWaalsContact C-N 3.29Å; V258-V260 PolarHBondContact O-N 3.19Å; V260-N262 VanDerWaalsContact C-N 3.29Å; V260-N262 PolarHBondContact O-N 3.35Å; V260-S263 PolarHBondContact O-N 3.26Å; V260-S263 VanDerWaalsContact O-N 3.11Å; V260-S263 PolarHBondContact O-OG 2.97Å; V260-M264 WeakPolarHBondContact O-CG 3.4Å; V260-M264 PolarHBondContact O-N 2.97Å; V260-W272 HydrophobicContact CB-CH2 4.45Å; V260-W272 HydrophobicContact CG1-CH2 4.42Å; V260-W272 HydrophobicContact CG1-CZ3 4.1Å
261	F	88.8	Confident	88.7	Confident	2 Å²	2	43.4 Å²	43.4	1%	0.009	21%	0.21	C	C	.	.	H	α-helix	trans	-54.7	-45.8	174.4	172.8	-107.2	0	0	0	111.7	Q103 C257 V258 S263 M264 K267 I269 W272	Q103-F261 HydrophobicContact CB-CE1 4.12Å; Q103-F261 HydrophobicContact CB-CZ 4.08Å; C257-F261 WeakPolarHBondContact O-CB 3.31Å; C257-F261 PolarHBondContact O-N 2.91Å; V258-F261 PolarHBondContact O-N 3.25Å; F261-S263 VanDerWaalsContact C-N 3.29Å; F261-S263 PolarHBondContact O-N 3.44Å; F261-M264 HydrophobicContact CD2-CE 3.92Å; F261-M264 HydrophobicContact CE2-CE 4.24Å; F261-M264 WeakPolarHBondContact O-CB 3.44Å; F261-M264 PolarHBondContact O-N 3.47Å; F261-K267 HydrophobicContact CZ-CB 4.34Å; F261-I269 HydrophobicContact CE2-CD1 4.36Å; F261-I269 HydrophobicContact CZ-CD1 4.18Å; F261-W272 HydrophobicContact CB-CD2 4.06Å; F261-W272 HydrophobicContact CB-CE3 3.91Å; F261-W272 HydrophobicContact CB-CH2 4.03Å; F261-W272 HydrophobicContact CB-CZ2 4.17Å; F261-W272 HydrophobicContact CB-CZ3 3.9Å; F261-W272 HydrophobicContact CD2-CB 3.68Å; F261-W272 AromaticContact CD2-CD2 3.55Å; F261-W272 HydrophobicContact CD2-CD2 3.55Å; F261-W272 AromaticContact CD2-CE3 3.79Å; F261-W272 HydrophobicContact CD2-CE3 3.79Å; F261-W272 AromaticContact CD2-CG 3.51Å; F261-W272 HydrophobicContact CD2-CG 3.51Å; F261-W272 HydrophobicContact CE2-CB 3.73Å; F261-W272 HydrophobicContact CE2-CD2 4.45Å; F261-W272 AromaticContact CE2-CG 3.95Å; F261-W272 HydrophobicContact CE2-CG 3.95Å; F261-W272 HydrophobicContact CG-CD2 4.21Å; F261-W272 HydrophobicContact CG-CE3 4.35Å; F261-W272 HydrophobicContact CG-CG 4.48Å
262	N	85.3	Confident	88.9	Confident	31 Å²	31	43.4 Å²	43.4	17%	0.166	21%	0.21	C	C	.	.	H	α-helix	trans	-72.8	-18.5	179.9	-79.3	-76	0	0	0	114.3	S102 E107 A108 V258 P259 V260 K267	S102-N262 PolarHBondContact OG-ND2 3.44Å; E107-N262 PolarHBondContact O-ND2 3.43Å; A108-N262 HydrophobicContact CB-CB 4.45Å; V258-N262 PolarHBondContact O-N 2.93Å; V258-N262 PolarHBondContact O-ND2 3.22Å; P259-N262 PolarHBondContact O-N 3.29Å; V260-N262 VanDerWaalsContact C-N 3.29Å; V260-N262 PolarHBondContact O-N 3.35Å; N262-K267 WeakPolarHBondContact O-CE 3.24Å; N262-K267 PolarHBondContact O-NZ 3.4Å
263	S	83.3	Confident	89	Confident	43 Å²	43	43.7 Å²	43.7	30%	0.301	22%	0.215	S	C	.	.	H	α-helix	trans	-81.8	-12.6	173.9	77.7	0	0	0	0	113.5	G45 V46 P259 V260 F261	G45-S263 CarbonylContact C-O 3.56Å; G45-S263 WeakPolarHBondContact CA-O 3.46Å; V46-S263 PolarHBondContact N-O 3.16Å; P259-S263 WeakPolarHBondContact O-CB 3.31Å; P259-S263 PolarHBondContact O-N 3.26Å; V260-S263 PolarHBondContact O-N 3.26Å; V260-S263 VanDerWaalsContact O-N 3.11Å; V260-S263 PolarHBondContact O-OG 2.97Å; F261-S263 VanDerWaalsContact C-N 3.29Å; F261-S263 PolarHBondContact O-N 3.44Å
264	M	85.4	Confident	89.2	Confident	9 Å²	9	49.2 Å²	49.2	4%	0.044	24%	0.239	C	C	.	.	B	Isolated β-bridge	trans	-70.6	145.9	-176.3	-61.8	-160.9	-45.2	0	0	112.6	V46 A51 V260 F261 R266 W272 V275	V46-M264 WeakPolarHBondContact O-CA 3.18Å; A51-M264 HydrophobicContact CB-CG 4.05Å; A51-M264 HydrophobicContact CB-SD 3.96Å; V260-M264 WeakPolarHBondContact O-CG 3.4Å; V260-M264 PolarHBondContact O-N 2.97Å; F261-M264 HydrophobicContact CD2-CE 3.92Å; F261-M264 HydrophobicContact CE2-CE 4.24Å; F261-M264 WeakPolarHBondContact O-CB 3.44Å; F261-M264 PolarHBondContact O-N 3.47Å; M264-R266 WeakPolarHBondContact CE-O 3.48Å; M264-R266 PolarHBondContact O-N 3.07Å; M264-W272 HydrophobicContact CE-CB 4.1Å; M264-W272 HydrophobicContact CE-CE3 4.06Å; M264-W272 HydrophobicContact SD-CE3 3.84Å; M264-W272 HydrophobicContact SD-CZ3 4.35Å; M264-V275 HydrophobicContact SD-CG2 4.1Å
265	K	85.7	Confident	89.3	Confident	133 Å²	133	49.2 Å²	49.2	58%	0.578	24%	0.239	S	C	*	.	S	Bend	trans	-54.7	-36.9	173.2	-68.5	-170	178.4	-166.6	0	113.3	G45 V46	G45-K265 WeakPolarHBondContact O-CE 3.44Å; G45-K265 WeakPolarHBondContact O-CG 3.29Å; V46-K265 PolarHBondContact O-N 3.35Å
266	R	86.3	Confident	89.7	Confident	185 Å²	185	48.7 Å²	48.7	70%	0.698	24%	0.236	S	C	*	.	S	Bend	trans	-123.3	95.6	180	-172.5	178.1	-178.1	177	3.9	110.2	M264 A268 P271	M264-R266 WeakPolarHBondContact CE-O 3.48Å; M264-R266 PolarHBondContact O-N 3.07Å; R266-A268 VanDerWaalsContact C-N 3.3Å; R266-A268 HydrophobicContact CG-CB 4.31Å; R266-A268 PolarHBondContact O-N 3.02Å; R266-P271 HydrophobicContact CB-CG 4.49Å; R266-P271 HydrophobicContact CG-CG 4.24Å
267	K	86.1	Confident	90.2	Very high	117 Å²	117	50.5 Å²	50.5	51%	0.509	25%	0.246	S	C	.	.			trans	-75.2	75.7	179.2	-52.7	-178.7	-165.2	-174.4	0	111.2	Q103 F261 N262	Q103-K267 PolarHBondContact NE2-O 2.93Å; F261-K267 HydrophobicContact CZ-CB 4.34Å; N262-K267 WeakPolarHBondContact O-CE 3.24Å; N262-K267 PolarHBondContact O-NZ 3.4Å
268	A	91.7	Very high	90.6	Very high	22 Å²	22	52.3 Å²	52.3	18%	0.182	26%	0.258	C	S	.	.			trans	-140.8	151.9	179.2	0	0	0	0	0	111.4	R266 K270 P271 W272	R266-A268 VanDerWaalsContact C-N 3.3Å; R266-A268 HydrophobicContact CG-CB 4.31Å; R266-A268 PolarHBondContact O-N 3.02Å; A268-K270 PolarHBondContact O-N 3.35Å; A268-P271 HydrophobicContact CB-CG 3.94Å; A268-P271 WeakPolarHBondContact O-CD 3.33Å; A268-P271 VanDerWaalsContact O-CG 3.25Å; A268-P271 WeakPolarHBondContact O-CG 3.5Å; A268-W272 WeakPolarHBondContact O-CB 3.29Å; A268-W272 PolarHBondContact O-N 3.07Å; A268-W272 VanDerWaalsContact O-N 3.14Å
269	I	93	Very high	91	Very high	43 Å²	43	52.3 Å²	52.3	22%	0.221	26%	0.258	C	S	.	.	H	α-helix	trans	-65.2	-35.9	-175.2	-53.3	-46.2	0	0	0	113.2	V96 G99 Y100 Q103 F261 W272 G273	V96-I269 HydrophobicContact CG1-CG2 4.32Å; G99-I269 WeakPolarHBondContact O-CD1 3.41Å; Y100-I269 HydrophobicContact CD2-CG1 4.36Å; Q103-I269 HydrophobicContact CB-CD1 4.21Å; Q103-I269 VanDerWaalsContact OE1-CD1 3.28Å; F261-I269 HydrophobicContact CE2-CD1 4.36Å; F261-I269 HydrophobicContact CZ-CD1 4.18Å; I269-W272 PolarHBondContact O-N 3.49Å; I269-G273 PolarHBondContact O-N 3.38Å
270	K	93.6	Very high	91.5	Very high	192 Å²	192	50 Å²	50	84%	0.835	24%	0.244	S	C	*	.	H	α-helix	trans	-59.4	-56.7	179	-70.5	-173.1	177.7	-177	0	113	A268 W272 G273 F274	A268-K270 PolarHBondContact O-N 3.35Å; K270-W272 VanDerWaalsContact C-N 3.3Å; K270-W272 PolarHBondContact O-N 3.3Å; K270-G273 PolarHBondContact O-N 3.45Å; K270-F274 PolarHBondContact O-N 3.08Å
271	P	94.2	Very high	92	Very high	31 Å²	31	53 Å²	53	20%	0.201	26%	0.258	C	S	.	.	H	α-helix	trans	-64.7	-34.3	175.9	24.1	-32.7	0	0	0	112.3	R266 A268 F274 V275	R266-P271 HydrophobicContact CB-CG 4.49Å; R266-P271 HydrophobicContact CG-CG 4.24Å; A268-P271 HydrophobicContact CB-CG 3.94Å; A268-P271 WeakPolarHBondContact O-CD 3.33Å; A268-P271 VanDerWaalsContact O-CG 3.25Å; A268-P271 WeakPolarHBondContact O-CG 3.5Å; P271-F274 WeakPolarHBondContact O-CB 3.35Å; P271-F274 PolarHBondContact O-N 3.25Å; P271-V275 WeakPolarHBondContact O-CG2 3.38Å; P271-V275 PolarHBondContact O-N 3.35Å
272	W	95.7	Very high	92.2	Very high	0 Å²	0	55.3 Å²	55.3	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-62.5	-45.3	175.6	179.5	-117.2	0	0	0	113.1	V55 L95 C257 V260 F261 M264 A268 I269 K270 F274 V275 V276	V55-W272 HydrophobicContact CG2-CH2 4.27Å; V55-W272 HydrophobicContact CG2-CZ3 4.46Å; L95-W272 PolarHBondContact O-NE1 2.91Å; C257-W272 HydrophobicContact CB-CH2 4.01Å; C257-W272 HydrophobicContact CB-CZ2 3.84Å; C257-W272 VanDerWaalsContact O-CH2 3.24Å; C257-W272 WeakPolarHBondContact O-CH2 3.41Å; V260-W272 HydrophobicContact CB-CH2 4.45Å; V260-W272 HydrophobicContact CG1-CH2 4.42Å; V260-W272 HydrophobicContact CG1-CZ3 4.1Å; F261-W272 HydrophobicContact CB-CD2 4.06Å; F261-W272 HydrophobicContact CB-CE3 3.91Å; F261-W272 HydrophobicContact CB-CH2 4.03Å; F261-W272 HydrophobicContact CB-CZ2 4.17Å; F261-W272 HydrophobicContact CB-CZ3 3.9Å; F261-W272 HydrophobicContact CD2-CB 3.68Å; F261-W272 AromaticContact CD2-CD2 3.55Å; F261-W272 HydrophobicContact CD2-CD2 3.55Å; F261-W272 AromaticContact CD2-CE3 3.79Å; F261-W272 HydrophobicContact CD2-CE3 3.79Å; F261-W272 AromaticContact CD2-CG 3.51Å; F261-W272 HydrophobicContact CD2-CG 3.51Å; F261-W272 HydrophobicContact CE2-CB 3.73Å; F261-W272 HydrophobicContact CE2-CD2 4.45Å; F261-W272 AromaticContact CE2-CG 3.95Å; F261-W272 HydrophobicContact CE2-CG 3.95Å; F261-W272 HydrophobicContact CG-CD2 4.21Å; F261-W272 HydrophobicContact CG-CE3 4.35Å; F261-W272 HydrophobicContact CG-CG 4.48Å; M264-W272 HydrophobicContact CE-CB 4.1Å; M264-W272 HydrophobicContact CE-CE3 4.06Å; M264-W272 HydrophobicContact SD-CE3 3.84Å; M264-W272 HydrophobicContact SD-CZ3 4.35Å; A268-W272 WeakPolarHBondContact O-CB 3.29Å; A268-W272 PolarHBondContact O-N 3.07Å; A268-W272 VanDerWaalsContact O-N 3.14Å; I269-W272 PolarHBondContact O-N 3.49Å; K270-W272 VanDerWaalsContact C-N 3.3Å; K270-W272 PolarHBondContact O-N 3.3Å; W272-F274 VanDerWaalsContact C-N 3.28Å; W272-F274 PolarHBondContact O-N 3.34Å; W272-V275 HydrophobicContact CE3-CB 4.41Å; W272-V275 HydrophobicContact CE3-CG1 4.35Å; W272-V275 HydrophobicContact CZ3-CG1 4.23Å; W272-V275 WeakPolarHBondContact O-CB 3.37Å; W272-V275 PolarHBondContact O-N 2.91Å; W272-V275 VanDerWaalsContact O-N 3.11Å; W272-V276 HydrophobicContact CD2-CG2 3.88Å; W272-V276 VanDerWaalsContact CE2-CG2 3.42Å; W272-V276 HydrophobicContact CE3-CG2 4.38Å; W272-V276 HydrophobicContact CG-CG2 4.4Å; W272-V276 HydrophobicContact CH2-CG2 4.11Å; W272-V276 HydrophobicContact CZ2-CG2 3.56Å; W272-V276 HydrophobicContact CZ3-CG2 4.48Å; W272-V276 WeakPolarHBondContact O-CG2 3.28Å; W272-V276 PolarHBondContact O-N 3.02Å
273	G	95.9	Very high	92.7	Very high	16 Å²	16	53.8 Å²	53.8	17%	0.165	26%	0.262	C	S	.	.	H	α-helix	trans	-59.7	-38.7	176.4	0	0	0	0	0	112.1	I269 K270 T277	I269-G273 PolarHBondContact O-N 3.38Å; K270-G273 PolarHBondContact O-N 3.45Å; G273-T277 VanDerWaalsContact O-CB 3.24Å; G273-T277 WeakPolarHBondContact O-CB 3.48Å; G273-T277 PolarHBondContact O-N 3.34Å; G273-T277 PolarHBondContact O-OG1 2.94Å
274	F	95.7	Very high	93.2	Very high	119 Å²	119	52.7 Å²	52.7	52%	0.522	25%	0.253	S	S	.	.	H	α-helix	trans	-62.6	-48.6	171.6	173.9	-96.5	0	0	0	112	K270 P271 W272 V276 T277 C278	K270-F274 PolarHBondContact O-N 3.08Å; P271-F274 WeakPolarHBondContact O-CB 3.35Å; P271-F274 PolarHBondContact O-N 3.25Å; W272-F274 VanDerWaalsContact C-N 3.28Å; W272-F274 PolarHBondContact O-N 3.34Å; F274-V276 PolarHBondContact O-N 3.43Å; F274-T277 PolarHBondContact O-N 3.06Å; F274-C278 WeakPolarHBondContact O-CB 3.26Å; F274-C278 PolarHBondContact O-N 3.38Å
275	V	95.9	Very high	93.7	Very high	0 Å²	0	58.6 Å²	58.6	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-57.1	-51.7	179.2	168.6	0	0	0	0	110.9	A48 A51 V52 V55 M264 P271 W272 S279	A48-V275 HydrophobicContact CB-CG2 3.94Å; A48-V275 WeakPolarHBondContact O-CG2 3.49Å; A51-V275 HydrophobicContact CB-CG1 3.82Å; A51-V275 HydrophobicContact CB-CG2 4.21Å; V52-V275 HydrophobicContact CG2-CB 4.22Å; V52-V275 HydrophobicContact CG2-CG1 4.01Å; V52-V275 HydrophobicContact CG2-CG2 4.22Å; V55-V275 HydrophobicContact CG2-CG1 4.23Å; M264-V275 HydrophobicContact SD-CG2 4.1Å; P271-V275 WeakPolarHBondContact O-CG2 3.38Å; P271-V275 PolarHBondContact O-N 3.35Å; W272-V275 HydrophobicContact CE3-CB 4.41Å; W272-V275 HydrophobicContact CE3-CG1 4.35Å; W272-V275 HydrophobicContact CZ3-CG1 4.23Å; W272-V275 WeakPolarHBondContact O-CB 3.37Å; W272-V275 PolarHBondContact O-N 2.91Å; W272-V275 VanDerWaalsContact O-N 3.11Å; V275-S279 VanDerWaalsContact O-CB 3.29Å; V275-S279 WeakPolarHBondContact O-CB 3.2Å; V275-S279 PolarHBondContact O-N 3.43Å; V275-S279 PolarHBondContact O-OG 3.48Å
276	V	96.6	Very high	94.1	Very high	0 Å²	0	52.2 Å²	52.2	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-61.3	-50.5	179.9	166.7	0	0	0	0	111	I92 L95 V96 W272 F274 C278 S279 M280	I92-V276 HydrophobicContact CG2-CG1 4.22Å; L95-V276 HydrophobicContact CB-CB 4.38Å; L95-V276 HydrophobicContact CB-CG1 3.55Å; L95-V276 HydrophobicContact CB-CG2 3.88Å; L95-V276 HydrophobicContact CD1-CG1 3.59Å; L95-V276 HydrophobicContact CD1-CG2 4.47Å; L95-V276 HydrophobicContact CG-CG1 4.21Å; V96-V276 HydrophobicContact CG2-CG1 4.49Å; W272-V276 HydrophobicContact CD2-CG2 3.88Å; W272-V276 VanDerWaalsContact CE2-CG2 3.42Å; W272-V276 HydrophobicContact CE3-CG2 4.38Å; W272-V276 HydrophobicContact CG-CG2 4.4Å; W272-V276 HydrophobicContact CH2-CG2 4.11Å; W272-V276 HydrophobicContact CZ2-CG2 3.56Å; W272-V276 HydrophobicContact CZ3-CG2 4.48Å; W272-V276 WeakPolarHBondContact O-CG2 3.28Å; W272-V276 PolarHBondContact O-N 3.02Å; F274-V276 PolarHBondContact O-N 3.43Å; V276-C278 PolarHBondContact O-N 2.7Å; V276-S279 PolarHBondContact O-N 3.07Å; V276-M280 HydrophobicContact CG1-CG 4.36Å; V276-M280 WeakPolarHBondContact O-CB 3.47Å; V276-M280 VanDerWaalsContact O-CG 3.28Å; V276-M280 WeakPolarHBondContact O-CG 3.38Å; V276-M280 PolarHBondContact O-N 2.94Å
277	T	96.2	Very high	94.6	Very high	56 Å²	56	43.4 Å²	43.4	34%	0.344	22%	0.217	S	C	.	.	H	α-helix	trans	-63.5	-46.4	-176.5	-55.3	0	0	0	0	111.3	G273 F274 S279 M280 I281	G273-T277 VanDerWaalsContact O-CB 3.24Å; G273-T277 WeakPolarHBondContact O-CB 3.48Å; G273-T277 PolarHBondContact O-N 3.34Å; G273-T277 PolarHBondContact O-OG1 2.94Å; F274-T277 PolarHBondContact O-N 3.06Å; T277-S279 VanDerWaalsContact C-N 3.35Å; T277-S279 PolarHBondContact O-N 2.75Å; T277-M280 PolarHBondContact O-N 2.95Å; T277-I281 HydrophobicContact CG2-CD1 3.91Å; T277-I281 VanDerWaalsContact O-CG1 3.28Å; T277-I281 WeakPolarHBondContact O-CG1 3.37Å; T277-I281 PolarHBondContact O-N 3.25Å
278	C	96.1	Very high	95	Very high	39 Å²	39	40 Å²	40	26%	0.264	20%	0.204	S	C	.	.	H	α-helix	trans	-61	-44.2	177	-177.4	0	0	0	0	111.4	V52 F274 V276 M280 I281 I282	V52-C278 HydrophobicContact CG2-CB 4.34Å; F274-C278 WeakPolarHBondContact O-CB 3.26Å; F274-C278 PolarHBondContact O-N 3.38Å; V276-C278 PolarHBondContact O-N 2.7Å; C278-M280 PolarHBondContact O-N 3.08Å; C278-I281 PolarHBondContact O-N 2.96Å; C278-I282 WeakPolarHBondContact O-CG1 3.46Å; C278-I282 PolarHBondContact O-N 2.85Å
279	S	95.4	Very high	95.2	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-61.1	-46.4	177.8	-55.5	0	0	0	0	112	V52 V275 V276 T277 I281 I282 C283	V52-S279 WeakPolarHBondContact CA-OG 3.16Å; V52-S279 PolarHBondContact O-OG 2.72Å; V275-S279 VanDerWaalsContact O-CB 3.29Å; V275-S279 WeakPolarHBondContact O-CB 3.2Å; V275-S279 PolarHBondContact O-N 3.43Å; V275-S279 PolarHBondContact O-OG 3.48Å; V276-S279 PolarHBondContact O-N 3.07Å; T277-S279 VanDerWaalsContact C-N 3.35Å; T277-S279 PolarHBondContact O-N 2.75Å; S279-I281 PolarHBondContact O-N 3.45Å; S279-I282 PolarHBondContact O-N 2.94Å; S279-C283 PolarHBondContact O-N 3.12Å; S279-C283 PolarHBondContact O-SG 3.28Å
280	M	95.6	Very high	95.3	Very high	0 Å²	0	37.7 Å²	37.7	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-68.4	-33.1	-178.7	-68.2	-53.2	115.9	0	0	112.5	V55 A59 L88 I91 I92 L95 F251 C253 V276 T277 C278 C283 L284	V55-M280 HydrophobicContact CG1-CE 3.62Å; A59-M280 HydrophobicContact CB-CE 4.49Å; L88-M280 HydrophobicContact CD1-CB 3.94Å; I91-M280 HydrophobicContact CG2-CG 4.12Å; I91-M280 HydrophobicContact CG2-SD 3.49Å; I91-M280 WeakPolarHBondContact CG2-SD 3.44Å; I92-M280 HydrophobicContact CD1-CB 3.98Å; I92-M280 HydrophobicContact CD1-CG 4.48Å; I92-M280 HydrophobicContact CG1-CB 3.75Å; I92-M280 HydrophobicContact CG1-CG 3.7Å; L95-M280 HydrophobicContact CD1-CE 3.79Å; L95-M280 HydrophobicContact CD1-CG 4.12Å; L95-M280 HydrophobicContact CD1-SD 4.04Å; F251-M280 HydrophobicContact CD1-SD 4.14Å; C253-M280 WeakPolarHBondContact SG-CE 3.31Å; V276-M280 HydrophobicContact CG1-CG 4.36Å; V276-M280 WeakPolarHBondContact O-CB 3.47Å; V276-M280 VanDerWaalsContact O-CG 3.28Å; V276-M280 WeakPolarHBondContact O-CG 3.38Å; V276-M280 PolarHBondContact O-N 2.94Å; T277-M280 PolarHBondContact O-N 2.95Å; C278-M280 PolarHBondContact O-N 3.08Å; M280-C283 PolarHBondContact O-N 3.49Å; M280-L284 VanDerWaalsContact O-CB 3.31Å; M280-L284 WeakPolarHBondContact O-CB 3.25Å; M280-L284 PolarHBondContact O-N 3.16Å
281	I	94.9	Very high	95.4	Very high	75 Å²	75	28.5 Å²	28.5	39%	0.385	15%	0.153	S	C	.	.	H	α-helix	trans	-65.7	-43.7	172.1	-70.4	168.7	0	0	0	111.1	T277 C278 S279 C283 L284 F285	T277-I281 HydrophobicContact CG2-CD1 3.91Å; T277-I281 VanDerWaalsContact O-CG1 3.28Å; T277-I281 WeakPolarHBondContact O-CG1 3.37Å; T277-I281 PolarHBondContact O-N 3.25Å; C278-I281 PolarHBondContact O-N 2.96Å; S279-I281 PolarHBondContact O-N 3.45Å; I281-C283 VanDerWaalsContact C-N 3.33Å; I281-C283 PolarHBondContact O-N 2.97Å; I281-L284 WeakPolarHBondContact O-CB 3.3Å; I281-L284 PolarHBondContact O-N 2.91Å; I281-F285 HydrophobicContact CG2-CD2 3.93Å; I281-F285 HydrophobicContact CG2-CE2 3.62Å; I281-F285 VanDerWaalsContact O-CD2 3.22Å; I281-F285 WeakPolarHBondContact O-CD2 3.33Å; I281-F285 PolarHBondContact O-N 3.21Å
282	I	94.4	Very high	95.4	Very high	50 Å²	50	28.5 Å²	28.5	26%	0.256	15%	0.152	S	C	.	.	H	α-helix	trans	-60.1	-46.8	175.7	-67.5	165.3	0	0	0	110.1	V52 V56 W208 C278 S279 L284 F285 V286	V52-I282 HydrophobicContact CG1-CD1 3.96Å; V56-I282 HydrophobicContact CG1-CG2 4.06Å; V56-I282 HydrophobicContact CG2-CB 4.24Å; V56-I282 HydrophobicContact CG2-CD1 4.24Å; V56-I282 HydrophobicContact CG2-CG2 4.27Å; W208-I282 HydrophobicContact CZ2-CG2 4.43Å; C278-I282 WeakPolarHBondContact O-CG1 3.46Å; C278-I282 PolarHBondContact O-N 2.85Å; S279-I282 PolarHBondContact O-N 2.94Å; I282-L284 VanDerWaalsContact C-N 3.32Å; I282-L284 PolarHBondContact O-N 3.42Å; I282-F285 PolarHBondContact O-N 2.7Å; I282-V286 PolarHBondContact O-N 3.11Å
283	C	95.1	Very high	95.4	Very high	0 Å²	0	29.2 Å²	29.2	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-61.8	-40.8	178	-61.3	0	0	0	0	111.8	L60 F251 S279 M280 I281 F285 V286 Y287	L60-C283 HydrophobicContact CD2-CB 4.04Å; F251-C283 HydrophobicContact CD1-CB 4.48Å; F251-C283 HydrophobicContact CE1-CB 3.96Å; S279-C283 PolarHBondContact O-N 3.12Å; S279-C283 PolarHBondContact O-SG 3.28Å; M280-C283 PolarHBondContact O-N 3.49Å; I281-C283 VanDerWaalsContact C-N 3.33Å; I281-C283 PolarHBondContact O-N 2.97Å; C283-F285 PolarHBondContact O-N 3.28Å; C283-V286 PolarHBondContact O-N 2.91Å; C283-Y287 HydrophobicContact CB-CD2 4.08Å; C283-Y287 HydrophobicContact CB-CE2 3.89Å; C283-Y287 VanDerWaalsContact O-CB 3.29Å; C283-Y287 WeakPolarHBondContact O-CB 3.48Å; C283-Y287 WeakPolarHBondContact O-CD2 3.15Å; C283-Y287 VanDerWaalsContact O-CG 3.23Å; C283-Y287 PolarHBondContact O-N 3.4Å
284	L	94.6	Very high	95.2	Very high	20 Å²	20	28.5 Å²	28.5	11%	0.105	15%	0.149	C	C	.	.	H	α-helix	trans	-56.2	-49.1	177.4	179.8	68.5	0	0	0	111.9	Q84 M85 L88 M280 I281 I282 Y287 I288	Q84-L284 HydrophobicContact CG-CD1 3.9Å; M85-L284 HydrophobicContact SD-CD1 3.88Å; M85-L284 HydrophobicContact SD-CD2 3.82Å; M85-L284 HydrophobicContact SD-CG 4.44Å; L88-L284 HydrophobicContact CD2-CB 4.38Å; L88-L284 HydrophobicContact CD2-CD1 4.13Å; L88-L284 HydrophobicContact CD2-CD2 3.82Å; L88-L284 HydrophobicContact CD2-CG 4.33Å; M280-L284 VanDerWaalsContact O-CB 3.31Å; M280-L284 WeakPolarHBondContact O-CB 3.25Å; M280-L284 PolarHBondContact O-N 3.16Å; I281-L284 WeakPolarHBondContact O-CB 3.3Å; I281-L284 PolarHBondContact O-N 2.91Å; I282-L284 VanDerWaalsContact C-N 3.32Å; I282-L284 PolarHBondContact O-N 3.42Å; L284-Y287 PolarHBondContact O-N 2.8Å; L284-I288 HydrophobicContact CD1-CD1 3.6Å; L284-I288 HydrophobicContact CD1-CG1 4.02Å; L284-I288 HydrophobicContact CD2-CD1 4.5Å; L284-I288 HydrophobicContact CG-CD1 3.83Å; L284-I288 HydrophobicContact CG-CG1 4.41Å; L284-I288 WeakPolarHBondContact O-CB 3.09Å; L284-I288 WeakPolarHBondContact O-CG1 3.38Å; L284-I288 PolarHBondContact O-N 3.32Å
285	F	94.5	Very high	95.1	Very high	132 Å²	132	23.7 Å²	23.7	58%	0.579	13%	0.128	S	C	*	.	H	α-helix	trans	-63.6	-43.4	-179.9	-78.6	-66.5	0	0	0	112.4	W208 I281 I282 C283 G289	W208-F285 HydrophobicContact CH2-CB 4.44Å; I281-F285 HydrophobicContact CG2-CD2 3.93Å; I281-F285 HydrophobicContact CG2-CE2 3.62Å; I281-F285 VanDerWaalsContact O-CD2 3.22Å; I281-F285 WeakPolarHBondContact O-CD2 3.33Å; I281-F285 PolarHBondContact O-N 3.21Å; I282-F285 PolarHBondContact O-N 2.7Å; C283-F285 PolarHBondContact O-N 3.28Å; F285-G289 PolarHBondContact O-N 3.21Å
286	V	95.5	Very high	94.8	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-61.7	-45.7	178.1	162	0	0	0	0	111.2	L60 L64 W208 T211 I282 C283 T290	L60-V286 HydrophobicContact CD1-CB 4.42Å; L60-V286 HydrophobicContact CD1-CG1 4.15Å; L60-V286 HydrophobicContact CD1-CG2 4.2Å; L60-V286 HydrophobicContact CD2-CB 3.92Å; L60-V286 HydrophobicContact CD2-CG1 3.45Å; L60-V286 VanDerWaalsContact CD2-CG1 3.45Å; L60-V286 HydrophobicContact CG-CG1 4.45Å; L64-V286 HydrophobicContact CD1-CG1 3.55Å; L64-V286 HydrophobicContact CD2-CG1 4.09Å; L64-V286 HydrophobicContact CG-CG1 4.46Å; W208-V286 HydrophobicContact CD2-CG2 3.88Å; W208-V286 HydrophobicContact CE3-CG2 4.33Å; W208-V286 HydrophobicContact CG-CG2 4.36Å; W208-V286 HydrophobicContact CH2-CG2 4.19Å; W208-V286 HydrophobicContact CZ2-CG2 3.72Å; W208-V286 HydrophobicContact CZ3-CG2 4.47Å; T211-V286 WeakPolarHBondContact OG1-CG1 3.42Å; I282-V286 PolarHBondContact O-N 3.11Å; C283-V286 PolarHBondContact O-N 2.91Å; V286-T290 WeakPolarHBondContact O-CB 3.39Å; V286-T290 PolarHBondContact O-N 2.93Å; V286-T290 PolarHBondContact O-OG1 2.76Å
287	Y	95.8	Very high	94.5	Very high	0 Å²	0	27.2 Å²	27.2	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-72.9	-39.6	-179.6	-70.8	-33.5	0	0	0	114.1	A59 L60 L64 F67 G250 F251 C283 L284 G291	A59-Y287 PolarHBondContact O-OH 2.67Å; L60-Y287 VanDerWaalsContact CA-OH 3.32Å; L60-Y287 WeakPolarHBondContact CA-OH 3.33Å; L60-Y287 HydrophobicContact CD2-CD1 4.25Å; L60-Y287 HydrophobicContact CD2-CE1 3.63Å; L60-Y287 HydrophobicContact CD2-CE2 4.15Å; L60-Y287 PolarHBondContact N-OH 3.02Å; L64-Y287 HydrophobicContact CB-CD1 4.35Å; L64-Y287 HydrophobicContact CB-CE1 3.87Å; L64-Y287 HydrophobicContact CD1-CD1 3.42Å; L64-Y287 VanDerWaalsContact CD1-CD1 3.42Å; L64-Y287 HydrophobicContact CD1-CE1 3.77Å; L64-Y287 HydrophobicContact CG-CE1 4.45Å; F67-Y287 HydrophobicContact CD1-CD1 4.35Å; F67-Y287 HydrophobicContact CD1-CG 4.09Å; F67-Y287 AromaticContact CD2-CD1 3.48Å; F67-Y287 HydrophobicContact CD2-CD1 3.48Å; F67-Y287 VanDerWaalsContact CD2-CD1 3.48Å; F67-Y287 AromaticContact CD2-CE1 3.94Å; F67-Y287 HydrophobicContact CD2-CE1 3.94Å; F67-Y287 AromaticContact CD2-CG 4Å; F67-Y287 HydrophobicContact CD2-CG 4Å; F67-Y287 HydrophobicContact CE1-CD1 4.15Å; F67-Y287 AromaticContact CE1-CD2 3.96Å; F67-Y287 HydrophobicContact CE1-CD2 3.96Å; F67-Y287 AromaticContact CE1-CG 3.64Å; F67-Y287 HydrophobicContact CE1-CG 3.64Å; F67-Y287 AromaticContact CE2-CD1 3.23Å; F67-Y287 HydrophobicContact CE2-CD1 3.23Å; F67-Y287 AromaticContact CE2-CD2 3.92Å; F67-Y287 HydrophobicContact CE2-CD2 3.92Å; F67-Y287 AromaticContact CE2-CE1 3.41Å; F67-Y287 HydrophobicContact CE2-CE1 3.41Å; F67-Y287 VanDerWaalsContact CE2-CE1 3.41Å; F67-Y287 AromaticContact CE2-CE2 3.98Å; F67-Y287 HydrophobicContact CE2-CE2 3.98Å; F67-Y287 AromaticContact CE2-CG 3.54Å; F67-Y287 HydrophobicContact CE2-CG 3.54Å; F67-Y287 AromaticContact CE2-CZ 3.75Å; F67-Y287 HydrophobicContact CG-CD1 4.04Å; F67-Y287 HydrophobicContact CG-CG 4.25Å; F67-Y287 AromaticContact CZ-CD1 3.61Å; F67-Y287 HydrophobicContact CZ-CD1 3.61Å; F67-Y287 AromaticContact CZ-CD2 3.43Å; F67-Y287 HydrophobicContact CZ-CD2 3.43Å; F67-Y287 VanDerWaalsContact CZ-CD2 3.43Å; F67-Y287 AromaticContact CZ-CE1 3.99Å; F67-Y287 HydrophobicContact CZ-CE1 3.99Å; F67-Y287 AromaticContact CZ-CE2 3.74Å; F67-Y287 HydrophobicContact CZ-CE2 3.74Å; F67-Y287 AromaticContact CZ-CG 3.34Å; F67-Y287 HydrophobicContact CZ-CG 3.34Å; G250-Y287 PolarHBondContact O-OH 3.36Å; F251-Y287 HydrophobicContact CD1-CD2 4.18Å; F251-Y287 AromaticContact CD1-CE2 3.81Å; F251-Y287 HydrophobicContact CD1-CE2 3.81Å; F251-Y287 HydrophobicContact CD2-CD2 4.08Å; F251-Y287 HydrophobicContact CD2-CE2 4.01Å; F251-Y287 AromaticContact CE1-CD2 3.62Å; F251-Y287 HydrophobicContact CE1-CD2 3.62Å; F251-Y287 AromaticContact CE1-CE2 3.71Å; F251-Y287 HydrophobicContact CE1-CE2 3.71Å; F251-Y287 AromaticContact CE2-CD2 3.5Å; F251-Y287 HydrophobicContact CE2-CD2 3.5Å; F251-Y287 VanDerWaalsContact CE2-CD2 3.5Å; F251-Y287 AromaticContact CE2-CE2 3.9Å; F251-Y287 HydrophobicContact CE2-CE2 3.9Å; F251-Y287 HydrophobicContact CE2-CG 4.45Å; F251-Y287 HydrophobicContact CG-CD2 4.42Å; F251-Y287 AromaticContact CG-CE2 3.99Å; F251-Y287 HydrophobicContact CG-CE2 3.99Å; F251-Y287 AromaticContact CZ-CD2 3.3Å; F251-Y287 HydrophobicContact CZ-CD2 3.3Å; F251-Y287 AromaticContact CZ-CE2 3.81Å; F251-Y287 HydrophobicContact CZ-CE2 3.81Å; F251-Y287 HydrophobicContact CZ-CG 4.4Å; C283-Y287 HydrophobicContact CB-CD2 4.08Å; C283-Y287 HydrophobicContact CB-CE2 3.89Å; C283-Y287 VanDerWaalsContact O-CB 3.29Å; C283-Y287 WeakPolarHBondContact O-CB 3.48Å; C283-Y287 WeakPolarHBondContact O-CD2 3.15Å; C283-Y287 VanDerWaalsContact O-CG 3.23Å; C283-Y287 PolarHBondContact O-N 3.4Å; L284-Y287 PolarHBondContact O-N 2.8Å; Y287-G291 WeakPolarHBondContact O-CA 3.47Å; Y287-G291 PolarHBondContact O-N 2.88Å
288	I	95.4	Very high	94.1	Very high	46 Å²	46	25.9 Å²	25.9	24%	0.236	14%	0.137	C	C	.	.	H	α-helix	trans	-64.5	-47.3	172.8	-73.1	179.4	0	0	0	109.4	V81 Q84 L284 T290 G291 V292	V81-I288 HydrophobicContact CG1-CD1 4.35Å; Q84-I288 VanDerWaalsContact OE1-CG1 3.28Å; L284-I288 HydrophobicContact CD1-CD1 3.6Å; L284-I288 HydrophobicContact CD1-CG1 4.02Å; L284-I288 HydrophobicContact CD2-CD1 4.5Å; L284-I288 HydrophobicContact CG-CD1 3.83Å; L284-I288 HydrophobicContact CG-CG1 4.41Å; L284-I288 WeakPolarHBondContact O-CB 3.09Å; L284-I288 WeakPolarHBondContact O-CG1 3.38Å; L284-I288 PolarHBondContact O-N 3.32Å; I288-T290 PolarHBondContact O-N 3.41Å; I288-G291 PolarHBondContact O-N 3.46Å; I288-V292 HydrophobicContact CG2-CG2 3.83Å; I288-V292 VanDerWaalsContact O-CB 3.24Å; I288-V292 WeakPolarHBondContact O-CB 3.44Å; I288-V292 WeakPolarHBondContact O-CG2 3.49Å; I288-V292 PolarHBondContact O-N 3.05Å
289	G	95.3	Very high	93.7	Very high	15 Å²	15	24.3 Å²	24.3	16%	0.155	13%	0.127	C	C	.	.	H	α-helix	trans	-56.8	-51	179.9	0	0	0	0	0	111.8	F285 C293	F285-G289 PolarHBondContact O-N 3.21Å; G289-C293 VanDerWaalsContact O-CB 3.31Å; G289-C293 WeakPolarHBondContact O-CB 3.41Å; G289-C293 PolarHBondContact O-N 3.4Å; G289-C293 VanDerWaalsContact O-N 3.16Å
290	T	95.9	Very high	93.2	Very high	0 Å²	0	27 Å²	27	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-67.6	-47	178.8	-57.9	0	0	0	0	111.8	L64 P68 T211 V214 V286 I288 G294 V306	L64-T290 HydrophobicContact CD1-CG2 3.93Å; L64-T290 WeakPolarHBondContact CD1-OG1 3.26Å; L64-T290 HydrophobicContact CG-CG2 4.23Å; P68-T290 HydrophobicContact CG-CG2 4.26Å; P68-T290 WeakPolarHBondContact CG-O 3.24Å; T211-T290 WeakPolarHBondContact CG2-OG1 3.45Å; T211-T290 PolarHBondContact OG1-OG1 2.84Å; V214-T290 HydrophobicContact CG1-CG2 4.43Å; V214-T290 HydrophobicContact CG2-CG2 4.4Å; V286-T290 WeakPolarHBondContact O-CB 3.39Å; V286-T290 PolarHBondContact O-N 2.93Å; V286-T290 PolarHBondContact O-OG1 2.76Å; I288-T290 PolarHBondContact O-N 3.41Å; T290-G294 WeakPolarHBondContact O-CA 3.48Å; T290-G294 PolarHBondContact O-N 3.23Å; T290-V306 HydrophobicContact CG2-CG1 4.44Å
291	G	95.3	Very high	92.8	Very high	0 Å²	0	32 Å²	32	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-62.3	-47	-178.1	0	0	0	0	0	113.4	Y287 I288 F295	Y287-G291 WeakPolarHBondContact O-CA 3.47Å; Y287-G291 PolarHBondContact O-N 2.88Å; I288-G291 PolarHBondContact O-N 3.46Å; G291-F295 WeakPolarHBondContact O-CB 3.32Å; G291-F295 PolarHBondContact O-N 3.16Å
292	V	94.3	Very high	92.6	Very high	31 Å²	31	29 Å²	29	19%	0.188	16%	0.158	C	C	.	.	H	α-helix	trans	-67.3	-56.6	179.2	176.2	0	0	0	0	110.6	F71 V77 V81 I288 F295 L296	F71-V292 HydrophobicContact CE2-CG2 3.86Å; V77-V292 HydrophobicContact CG1-CG1 4.14Å; V77-V292 HydrophobicContact CG1-CG2 3.85Å; V77-V292 HydrophobicContact CG2-CG1 4.41Å; V81-V292 HydrophobicContact CG2-CG2 4.04Å; I288-V292 HydrophobicContact CG2-CG2 3.83Å; I288-V292 VanDerWaalsContact O-CB 3.24Å; I288-V292 WeakPolarHBondContact O-CB 3.44Å; I288-V292 WeakPolarHBondContact O-CG2 3.49Å; I288-V292 PolarHBondContact O-N 3.05Å; V292-F295 PolarHBondContact O-N 2.86Å; V292-L296 HydrophobicContact CG1-CD1 3.72Å; V292-L296 HydrophobicContact CG1-CG 4.37Å; V292-L296 WeakPolarHBondContact O-CB 3.49Å; V292-L296 VanDerWaalsContact O-CG 3.25Å; V292-L296 WeakPolarHBondContact O-CG 3.15Å; V292-L296 PolarHBondContact O-N 3.35Å
293	C	94.3	Very high	92.4	Very high	15 Å²	15	30.4 Å²	30.4	10%	0.101	17%	0.166	C	C	.	.	H	α-helix	trans	-67.2	-40.3	-175.3	-70.2	0	0	0	0	111.9	V214 I215 Y218 G289 L296 T297	V214-C293 HydrophobicContact CG1-CB 4.01Å; I215-C293 HydrophobicContact CG1-CB 4.25Å; Y218-C293 HydrophobicContact CD1-CB 4.22Å; Y218-C293 HydrophobicContact CG-CB 4.02Å; G289-C293 VanDerWaalsContact O-CB 3.31Å; G289-C293 WeakPolarHBondContact O-CB 3.41Å; G289-C293 PolarHBondContact O-N 3.4Å; G289-C293 VanDerWaalsContact O-N 3.16Å; C293-L296 PolarHBondContact O-N 3.22Å; C293-T297 WeakPolarHBondContact O-CB 3.25Å; C293-T297 PolarHBondContact O-N 2.62Å; C293-T297 PolarHBondContact O-OG1 3.26Å
294	G	93.5	Very high	92.2	Very high	0 Å²	0	33.1 Å²	33.1	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-63.2	-45	175.5	0	0	0	0	0	112.3	T290 T297 F298	T290-G294 WeakPolarHBondContact O-CA 3.48Å; T290-G294 PolarHBondContact O-N 3.23Å; G294-T297 PolarHBondContact O-N 3.38Å; G294-F298 WeakPolarHBondContact O-CD2 3.49Å; G294-F298 PolarHBondContact O-N 3.14Å; G294-F298 VanDerWaalsContact O-N 3.17Å
295	F	91.9	Very high	92.2	Very high	19 Å²	19	32.4 Å²	32.4	8%	0.083	17%	0.174	C	C	.	.	H	α-helix	trans	-66.4	-42	177.2	175.3	-97.7	0	0	0	112.2	F71 V77 G291 V292 T297 F298 G299	F71-F295 HydrophobicContact CB-CB 4.07Å; F71-F295 HydrophobicContact CB-CD2 4.31Å; F71-F295 HydrophobicContact CB-CG 4.12Å; V77-F295 HydrophobicContact CG2-CD1 3.48Å; V77-F295 VanDerWaalsContact CG2-CD1 3.48Å; V77-F295 HydrophobicContact CG2-CE1 4.03Å; V77-F295 HydrophobicContact CG2-CG 4.49Å; G291-F295 WeakPolarHBondContact O-CB 3.32Å; G291-F295 PolarHBondContact O-N 3.16Å; V292-F295 PolarHBondContact O-N 2.86Å; F295-T297 PolarHBondContact O-N 2.92Å; F295-F298 PolarHBondContact O-N 2.94Å; F295-G299 WeakPolarHBondContact O-CA 3.43Å; F295-G299 PolarHBondContact O-N 3.41Å
296	L	90.3	Very high	92.1	Very high	64 Å²	64	26.1 Å²	26.1	34%	0.335	15%	0.147	S	C	.	.	H	α-helix	trans	-67.8	-23	178.3	-68.6	175.3	0	0	0	112.8	V77 Y218 V292 C293	V77-L296 HydrophobicContact CG2-CD2 3.87Å; V77-L296 HydrophobicContact CG2-CG 4Å; Y218-L296 HydrophobicContact CD2-CB 3.87Å; Y218-L296 HydrophobicContact CE1-CD1 4.35Å; Y218-L296 HydrophobicContact CE2-CB 3.36Å; Y218-L296 HydrophobicContact CE2-CD1 4.06Å; Y218-L296 HydrophobicContact CE2-CG 4.35Å; V292-L296 HydrophobicContact CG1-CD1 3.72Å; V292-L296 HydrophobicContact CG1-CG 4.37Å; V292-L296 WeakPolarHBondContact O-CB 3.49Å; V292-L296 VanDerWaalsContact O-CG 3.25Å; V292-L296 WeakPolarHBondContact O-CG 3.15Å; V292-L296 PolarHBondContact O-N 3.35Å; C293-L296 PolarHBondContact O-N 3.22Å
297	T	89.6	Confident	92	Very high	9 Å²	9	26.1 Å²	26.1	6%	0.055	15%	0.147	C	C	.	.	H	α-helix	trans	-77.5	-44.9	176.5	-56.8	0	0	0	0	112	M225 C293 G294 F295	M225-T297 HydrophobicContact CE-CG2 3.38Å; C293-T297 WeakPolarHBondContact O-CB 3.25Å; C293-T297 PolarHBondContact O-N 2.62Å; C293-T297 PolarHBondContact O-OG1 3.26Å; G294-T297 PolarHBondContact O-N 3.38Å; F295-T297 PolarHBondContact O-N 2.92Å
298	F	88.9	Confident	91.8	Very high	29 Å²	29	27.8 Å²	27.8	13%	0.127	16%	0.155	C	C	.	.	H	α-helix	trans	-110.8	-12.2	-170.4	-60.7	-69.4	0	0	0	114.8	M225 G294 F295 S300 N301 V302 V306 S309 Y310	M225-F298 HydrophobicContact CE-CE1 3.48Å; M225-F298 VanDerWaalsContact CE-CE1 3.48Å; M225-F298 HydrophobicContact CE-CE2 4.39Å; M225-F298 HydrophobicContact CE-CZ 3.39Å; G294-F298 WeakPolarHBondContact O-CD2 3.49Å; G294-F298 PolarHBondContact O-N 3.14Å; G294-F298 VanDerWaalsContact O-N 3.17Å; F295-F298 PolarHBondContact O-N 2.94Å; F298-S300 PolarHBondContact O-N 2.86Å; F298-N301 PolarHBondContact O-N 3.31Å; F298-N301 VanDerWaalsContact O-N 3.16Å; F298-V302 HydrophobicContact CB-CB 3.75Å; F298-V302 HydrophobicContact CB-CG2 4.08Å; F298-V302 HydrophobicContact CD2-CG2 4.1Å; F298-V302 HydrophobicContact CG-CG2 4.43Å; F298-V306 HydrophobicContact CD2-CG2 4.11Å; F298-V306 HydrophobicContact CE2-CG2 3.92Å; F298-S309 VanDerWaalsContact CE1-O 3.23Å; F298-S309 WeakPolarHBondContact CE1-O 3.45Å; F298-Y310 HydrophobicContact CE2-CD2 4Å; F298-Y310 HydrophobicContact CE2-CE1 4.15Å; F298-Y310 AromaticContact CE2-CE2 3.51Å; F298-Y310 HydrophobicContact CE2-CE2 3.51Å; F298-Y310 AromaticContact CE2-CZ 3.57Å; F298-Y310 AromaticContact CZ-CD1 3.89Å; F298-Y310 HydrophobicContact CZ-CD1 3.89Å; F298-Y310 AromaticContact CZ-CD2 3.81Å; F298-Y310 HydrophobicContact CZ-CD2 3.81Å; F298-Y310 AromaticContact CZ-CE1 3.76Å; F298-Y310 HydrophobicContact CZ-CE1 3.76Å; F298-Y310 AromaticContact CZ-CE2 3.71Å; F298-Y310 HydrophobicContact CZ-CE2 3.71Å; F298-Y310 AromaticContact CZ-CG 3.91Å; F298-Y310 HydrophobicContact CZ-CG 3.91Å; F298-Y310 AromaticContact CZ-CZ 3.66Å
299	G	86.6	Confident	91.6	Very high	5 Å²	5	26.8 Å²	26.8	5%	0.052	15%	0.152	C	C	.	.	G	3₁₀ helix	trans	57.1	-133.7	-178.2	0	0	0	0	0	112.9	F295 N301	F295-G299 WeakPolarHBondContact O-CA 3.43Å; F295-G299 PolarHBondContact O-N 3.41Å; G299-N301 PolarHBondContact O-N 2.99Å
300	S	85.1	Confident	91.4	Very high	57 Å²	57	26.2 Å²	26.2	40%	0.399	15%	0.145	S	C	.	.	G	3₁₀ helix	trans	-70.9	-16	178.5	58.4	0	0	0	0	114.3	S72 A230 F298 V302	S72-S300 WeakPolarHBondContact OG-CA 3.38Å; A230-S300 WeakPolarHBondContact CB-OG 3.39Å; F298-S300 PolarHBondContact O-N 2.86Å; S300-V302 VanDerWaalsContact C-N 3.3Å
301	N	87.6	Confident	90.9	Very high	105 Å²	105	28.5 Å²	28.5	56%	0.561	16%	0.16	S	C	*	.	G	3₁₀ helix	trans	-89.5	4.5	-175.3	-62.1	-32.6	0	0	0	112.9	F298 G299 N303	F298-N301 PolarHBondContact O-N 3.31Å; F298-N301 VanDerWaalsContact O-N 3.16Å; G299-N301 PolarHBondContact O-N 2.99Å; N301-N303 PolarHBondContact O-N 3.43Å
302	V	90.2	Very high	90.2	Very high	13 Å²	13	29.8 Å²	29.8	8%	0.079	17%	0.169	C	C	.	.			trans	-62.4	130.6	178.5	69.7	0	0	0	0	111	P68 A69 F298 S300 V306	P68-V302 HydrophobicContact CB-CG1 4.48Å; P68-V302 HydrophobicContact CB-CG2 3.67Å; A69-V302 HydrophobicContact CB-CG1 4.12Å; F298-V302 HydrophobicContact CB-CB 3.75Å; F298-V302 HydrophobicContact CB-CG2 4.08Å; F298-V302 HydrophobicContact CD2-CG2 4.1Å; F298-V302 HydrophobicContact CG-CG2 4.43Å; S300-V302 VanDerWaalsContact C-N 3.3Å; V302-V306 HydrophobicContact CG2-CG2 4.14Å
303	N	91.6	Very high	89.6	Confident	79 Å²	79	33.5 Å²	33.5	42%	0.422	19%	0.187	S	C	.	.			trans	-67.8	158.5	172.8	-70	-69.1	0	0	0	110.7	N301 D305 M308 S309	N301-N303 PolarHBondContact O-N 3.43Å; N303-D305 WeakPolarHBondContact CB-O 3.31Å; N303-D305 CarbonylContact O-C 3.58Å; N303-D305 PolarHBondContact O-N 3.41Å; N303-D305 VanDerWaalsContact O-N 3.16Å; N303-M308 HydrophobicContact CB-CB 4.25Å; N303-M308 PolarHBondContact ND2-O 2.92Å; N303-S309 WeakPolarHBondContact CB-OG 3.39Å; N303-S309 PolarHBondContact N-OG 3.21Å; N303-S309 PolarHBondContact ND2-OG 2.87Å; N303-S309 VanDerWaalsContact ND2-OG 3.1Å
304	Q	91.3	Very high	89.2	Confident	57 Å²	57	33.9 Å²	33.9	27%	0.266	19%	0.188	S	C	.	.	S	Bend	trans	-56.1	-32.1	174.4	-68.3	-62.4	-33.2	0	0	112	N66 I387	N66-Q304 WeakPolarHBondContact CA-O 3.21Å; N66-Q304 PolarHBondContact ND2-O 3.18Å; Q304-I387 HydrophobicContact CB-CG2 3.95Å
305	D	93.4	Very high	89	Confident	4 Å²	4	39.4 Å²	39.4	2%	0.021	22%	0.217	C	C	.	.	S	Bend	trans	-104.6	113.1	165.9	-175.3	-32.9	0	0	0	109.1	L65 Q148 N303 L307 M308	L65-D305 WeakPolarHBondContact CD1-OD2 3.41Å; Q148-D305 VanDerWaalsContact NE2-CG 3.27Å; Q148-D305 PolarHBondContact NE2-OD1 3.3Å; Q148-D305 PolarHBondContact NE2-OD2 2.91Å; N303-D305 WeakPolarHBondContact CB-O 3.31Å; N303-D305 CarbonylContact O-C 3.58Å; N303-D305 PolarHBondContact O-N 3.41Å; N303-D305 VanDerWaalsContact O-N 3.16Å; D305-L307 PolarHBondContact O-N 2.96Å; D305-L307 WeakPolarHBondContact OD1-CB 3Å; D305-L307 PolarHBondContact OD1-N 3.48Å; D305-M308 HydrophobicContact CB-CB 4.37Å; D305-M308 HydrophobicContact CB-CG 3.82Å; D305-M308 WeakPolarHBondContact O-CB 3.38Å; D305-M308 PolarHBondContact O-N 3.29Å
306	V	93.6	Very high	89	Confident	0 Å²	0	40 Å²	40	0%	0	23%	0.225	C	C	.	.	G	3₁₀ helix	trans	-59.2	-32.8	-177.2	70.6	0	0	0	0	113	L65 P68 T290 F298 V302 M308 S309 Y310	L65-V306 HydrophobicContact CD2-CG1 4.34Å; L65-V306 PolarHBondContact O-N 3.48Å; P68-V306 HydrophobicContact CB-CB 4.32Å; P68-V306 HydrophobicContact CB-CG2 4.11Å; P68-V306 HydrophobicContact CG-CB 3.85Å; P68-V306 HydrophobicContact CG-CG1 4.33Å; P68-V306 HydrophobicContact CG-CG2 3.78Å; T290-V306 HydrophobicContact CG2-CG1 4.44Å; F298-V306 HydrophobicContact CD2-CG2 4.11Å; F298-V306 HydrophobicContact CE2-CG2 3.92Å; V302-V306 HydrophobicContact CG2-CG2 4.14Å; V306-M308 PolarHBondContact O-N 3.36Å; V306-S309 VanDerWaalsContact O-CB 3.3Å; V306-S309 WeakPolarHBondContact O-CB 3.43Å; V306-S309 PolarHBondContact O-N 3.33Å; V306-S309 PolarHBondContact O-OG 2.88Å; V306-Y310 HydrophobicContact CG2-CE2 4.1Å; V306-Y310 WeakPolarHBondContact O-CD2 3.45Å
307	L	93.2	Very high	89.1	Confident	0 Å²	0	37 Å²	37	0%	0	21%	0.209	C	C	.	.	G	3₁₀ helix	trans	-69.4	-17.8	-179.5	-67.1	179.2	0	0	0	112.8	L65 V210 D305 S309 Y310 V317 A320 R321 I324	L65-L307 HydrophobicContact CD2-CD1 3.72Å; L65-L307 HydrophobicContact CD2-CG 3.86Å; V210-L307 HydrophobicContact CG1-CD1 4.41Å; V210-L307 HydrophobicContact CG1-CD2 4.43Å; D305-L307 PolarHBondContact O-N 2.96Å; D305-L307 WeakPolarHBondContact OD1-CB 3Å; D305-L307 PolarHBondContact OD1-N 3.48Å; L307-S309 VanDerWaalsContact C-N 3.29Å; L307-Y310 HydrophobicContact CD2-CD2 4.41Å; L307-V317 HydrophobicContact CD2-CG1 4.31Å; L307-A320 HydrophobicContact CD2-CB 4.27Å; L307-R321 HydrophobicContact CD1-CG 4.38Å; L307-R321 PolarHBondContact O-NH2 2.91Å; L307-R321 VanDerWaalsContact O-NH2 3.1Å; L307-I324 HydrophobicContact CD1-CG1 3.79Å
308	M	91.3	Very high	89.2	Confident	35 Å²	35	37.1 Å²	37.1	17%	0.172	21%	0.212	C	C	.	.	G	3₁₀ helix	trans	-79.2	-12.9	172	-62.5	-62.4	-79.1	0	0	113.1	D147 R151 N303 D305 V306	D147-M308 HydrophobicContact CB-CE 3.98Å; D147-M308 HydrophobicContact CB-SD 3.95Å; R151-M308 HydrophobicContact CG-CE 4Å; R151-M308 HydrophobicContact CG-SD 3.54Å; R151-M308 VanDerWaalsContact CG-SD 3.54Å; N303-M308 HydrophobicContact CB-CB 4.25Å; N303-M308 PolarHBondContact ND2-O 2.92Å; D305-M308 HydrophobicContact CB-CB 4.37Å; D305-M308 HydrophobicContact CB-CG 3.82Å; D305-M308 WeakPolarHBondContact O-CB 3.38Å; D305-M308 PolarHBondContact O-N 3.29Å; V306-M308 PolarHBondContact O-N 3.36Å
309	S	90.9	Very high	89.4	Confident	25 Å²	25	39.9 Å²	39.9	18%	0.175	23%	0.227	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.8	-17.8	175.2	-47.2	0	0	0	0	112.5	F298 N303 V306 L307	F298-S309 VanDerWaalsContact CE1-O 3.23Å; F298-S309 WeakPolarHBondContact CE1-O 3.45Å; N303-S309 WeakPolarHBondContact CB-OG 3.39Å; N303-S309 PolarHBondContact N-OG 3.21Å; N303-S309 PolarHBondContact ND2-OG 2.87Å; N303-S309 VanDerWaalsContact ND2-OG 3.1Å; V306-S309 VanDerWaalsContact O-CB 3.3Å; V306-S309 WeakPolarHBondContact O-CB 3.43Å; V306-S309 PolarHBondContact O-N 3.33Å; V306-S309 PolarHBondContact O-OG 2.88Å; L307-S309 VanDerWaalsContact C-N 3.29Å
310	Y	90.3	Very high	89.7	Confident	4 Å²	4	39.7 Å²	39.7	2%	0.016	23%	0.225	C	C	.	.	S	Bend	trans	-84.9	147.9	173.6	-70.2	-84.5	0	0	0	111.1	V214 K217 M225 F298 V306 L307 V317 R321	V214-Y310 HydrophobicContact CG2-CE2 4.27Å; K217-Y310 HydrophobicContact CB-CE1 3.61Å; K217-Y310 HydrophobicContact CD-CE1 4.35Å; K217-Y310 HydrophobicContact CG-CD1 4.45Å; K217-Y310 HydrophobicContact CG-CE1 3.81Å; M225-Y310 HydrophobicContact CE-CD1 3.62Å; M225-Y310 HydrophobicContact CE-CE1 3.41Å; M225-Y310 VanDerWaalsContact CE-CE1 3.41Å; M225-Y310 HydrophobicContact SD-CD1 3.94Å; M225-Y310 HydrophobicContact SD-CE1 3.99Å; F298-Y310 HydrophobicContact CE2-CD2 4Å; F298-Y310 HydrophobicContact CE2-CE1 4.15Å; F298-Y310 AromaticContact CE2-CE2 3.51Å; F298-Y310 HydrophobicContact CE2-CE2 3.51Å; F298-Y310 AromaticContact CE2-CZ 3.57Å; F298-Y310 AromaticContact CZ-CD1 3.89Å; F298-Y310 HydrophobicContact CZ-CD1 3.89Å; F298-Y310 AromaticContact CZ-CD2 3.81Å; F298-Y310 HydrophobicContact CZ-CD2 3.81Å; F298-Y310 AromaticContact CZ-CE1 3.76Å; F298-Y310 HydrophobicContact CZ-CE1 3.76Å; F298-Y310 AromaticContact CZ-CE2 3.71Å; F298-Y310 HydrophobicContact CZ-CE2 3.71Å; F298-Y310 AromaticContact CZ-CG 3.91Å; F298-Y310 HydrophobicContact CZ-CG 3.91Å; F298-Y310 AromaticContact CZ-CZ 3.66Å; V306-Y310 HydrophobicContact CG2-CE2 4.1Å; V306-Y310 WeakPolarHBondContact O-CD2 3.45Å; L307-Y310 HydrophobicContact CD2-CD2 4.41Å; Y310-V317 HydrophobicContact CD1-CG2 3.97Å; Y310-V317 HydrophobicContact CG-CG1 4.26Å; Y310-V317 HydrophobicContact CG-CG2 3.94Å; Y310-R321 PolarHBondContact O-NH2 3.42Å
311	P	86.2	Confident	90.2	Very high	47 Å²	47	37 Å²	37	31%	0.305	21%	0.206	S	C	.	.			trans	-67.6	159	178	34.6	-38.8	0	0	0	111.1	D313 R321	P311-D313 WeakPolarHBondContact CB-OD1 3.22Å; P311-D313 WeakPolarHBondContact CG-OD1 3.45Å; P311-R321 PolarHBondContact O-NH2 3.26Å
312	P	81.3	Confident	90.4	Very high	28 Å²	28	33.3 Å²	33.3	18%	0.182	19%	0.19	C	C	.	.	S	Bend	trans	-74.9	-27.9	-173.7	27.6	-32.8	0	0	0	114.2	A154 A155 D314 R321	A154-P312 HydrophobicContact CB-CB 4.26Å; A155-P312 WeakPolarHBondContact CB-O 3.48Å; P312-D314 VanDerWaalsContact C-N 3.34Å; P312-D314 PolarHBondContact O-N 2.7Å; P312-R321 PolarHBondContact O-NH1 3.42Å
313	D	81.4	Confident	90.5	Very high	109 Å²	109	35.4 Å²	35.4	58%	0.583	20%	0.198	S	C	*	.	S	Bend	trans	-74.2	-13.8	-170.5	59.6	-37.3	0	0	0	115.3	P311 I315	P311-D313 WeakPolarHBondContact CB-OD1 3.22Å; P311-D313 WeakPolarHBondContact CG-OD1 3.45Å; D313-I315 PolarHBondContact O-N 2.78Å
314	D	85.8	Confident	90.5	Very high	23 Å²	23	31.7 Å²	31.7	12%	0.123	18%	0.178	C	C	.	.			trans	-77.3	115.7	178.9	-179	-6.7	0	0	0	112.6	K217 P312 A316 V317 A318	K217-D314 WeakPolarHBondContact CE-OD2 3.36Å; K217-D314 IonicContact NZ-OD1 3.88Å; K217-D314 IonicContact NZ-OD2 2.61Å; K217-D314 PolarHBondContact NZ-OD2 3.34Å; P312-D314 VanDerWaalsContact C-N 3.34Å; P312-D314 PolarHBondContact O-N 2.7Å; D314-A316 VanDerWaalsContact C-N 3.32Å; D314-A316 PolarHBondContact O-N 3.11Å; D314-A316 WeakPolarHBondContact OD1-CB 3.45Å; D314-A316 PolarHBondContact OD1-N 3Å; D314-V317 HydrophobicContact CB-CB 4.05Å; D314-V317 HydrophobicContact CB-CG2 4.06Å; D314-V317 PolarHBondContact O-N 3.45Å; D314-V317 VanDerWaalsContact OD2-CG2 3.24Å; D314-V317 WeakPolarHBondContact OD2-CG2 3.2Å; D314-A318 WeakPolarHBondContact O-CB 3.35Å; D314-A318 PolarHBondContact O-N 3.3Å
315	I	88.8	Confident	90.6	Very high	116 Å²	116	29.7 Å²	29.7	60%	0.595	17%	0.17	S	C	*	.	H	α-helix	trans	-57.8	-40.3	179.4	-59.8	172.6	0	0	0	112.3	D313 A318 L319	D313-I315 PolarHBondContact O-N 2.78Å; I315-A318 PolarHBondContact O-N 3.35Å; I315-L319 HydrophobicContact CG2-CD1 4.4Å; I315-L319 WeakPolarHBondContact O-CG 3.31Å; I315-L319 PolarHBondContact O-N 3.33Å
316	A	91.8	Very high	90.3	Very high	32 Å²	32	32.7 Å²	32.7	26%	0.264	19%	0.186	S	C	.	.	H	α-helix	trans	-67.9	-41	-178.6	0	0	0	0	0	110.9	Y209 V213 D314 A320	Y209-A316 PolarHBondContact OH-O 3.01Å; V213-A316 HydrophobicContact CG1-CB 4.44Å; V213-A316 HydrophobicContact CG2-CB 4.34Å; D314-A316 VanDerWaalsContact C-N 3.32Å; D314-A316 PolarHBondContact O-N 3.11Å; D314-A316 WeakPolarHBondContact OD1-CB 3.45Å; D314-A316 PolarHBondContact OD1-N 3Å; A316-A320 PolarHBondContact O-N 2.84Å; A316-A320 VanDerWaalsContact O-N 3.07Å
317	V	92.3	Very high	90.1	Very high	0 Å²	0	32.7 Å²	32.7	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-67.2	-43.1	174	175.8	0	0	0	0	110.1	V213 L307 Y310 D314 L319 A320 R321	V213-V317 HydrophobicContact CG1-CG2 3.98Å; L307-V317 HydrophobicContact CD2-CG1 4.31Å; Y310-V317 HydrophobicContact CD1-CG2 3.97Å; Y310-V317 HydrophobicContact CG-CG1 4.26Å; Y310-V317 HydrophobicContact CG-CG2 3.94Å; D314-V317 HydrophobicContact CB-CB 4.05Å; D314-V317 HydrophobicContact CB-CG2 4.06Å; D314-V317 PolarHBondContact O-N 3.45Å; D314-V317 VanDerWaalsContact OD2-CG2 3.24Å; D314-V317 WeakPolarHBondContact OD2-CG2 3.2Å; V317-L319 VanDerWaalsContact C-N 3.33Å; V317-L319 PolarHBondContact O-N 3.08Å; V317-A320 CarbonylContact O-C 3.55Å; V317-A320 WeakPolarHBondContact O-CA 3.29Å; V317-A320 VanDerWaalsContact O-CB 3.26Å; V317-A320 WeakPolarHBondContact O-CB 3.25Å; V317-A320 PolarHBondContact O-N 3.34Å; V317-R321 HydrophobicContact CG1-CG 4.4Å; V317-R321 VanDerWaalsContact O-CG 3.28Å; V317-R321 WeakPolarHBondContact O-CG 3.28Å; V317-R321 PolarHBondContact O-N 2.91Å
318	A	92.1	Very high	90	Very high	12 Å²	12	32.7 Å²	32.7	10%	0.099	19%	0.186	C	C	.	.	H	α-helix	trans	-57.6	-43.1	176.9	0	0	0	0	0	112.4	L152 A155 D314 I315 A320 R321 A322	L152-A318 HydrophobicContact CD1-CB 3.94Å; A155-A318 HydrophobicContact CB-CB 4.3Å; D314-A318 WeakPolarHBondContact O-CB 3.35Å; D314-A318 PolarHBondContact O-N 3.3Å; I315-A318 PolarHBondContact O-N 3.35Å; A318-A320 VanDerWaalsContact C-N 3.31Å; A318-A320 PolarHBondContact O-N 3.32Å; A318-R321 WeakPolarHBondContact O-CB 3.44Å; A318-R321 PolarHBondContact O-N 3.42Å; A318-A322 PolarHBondContact O-N 3.26Å
319	L	92.6	Very high	89.8	Confident	87 Å²	87	31.6 Å²	31.6	46%	0.455	18%	0.181	S	C	.	.	H	α-helix	trans	-62.2	-38.3	171.8	-73.2	175	0	0	0	111.9	Y209 I315 V317 R321 A322 F323	Y209-L319 HydrophobicContact CE1-CB 3.76Å; Y209-L319 WeakPolarHBondContact OH-CB 3.46Å; I315-L319 HydrophobicContact CG2-CD1 4.4Å; I315-L319 WeakPolarHBondContact O-CG 3.31Å; I315-L319 PolarHBondContact O-N 3.33Å; V317-L319 VanDerWaalsContact C-N 3.33Å; V317-L319 PolarHBondContact O-N 3.08Å; L319-R321 VanDerWaalsContact C-N 3.35Å; L319-A322 PolarHBondContact O-N 3.45Å; L319-F323 VanDerWaalsContact O-CD2 3.24Å; L319-F323 WeakPolarHBondContact O-CD2 3.43Å; L319-F323 PolarHBondContact O-N 2.96Å
320	A	93.9	Very high	89.4	Confident	0 Å²	0	31.7 Å²	31.7	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-63.8	-41.6	176.5	0	0	0	0	0	111	Y209 V210 V213 L307 A316 V317 A318 A322 F323 I324	Y209-A320 HydrophobicContact CD1-CB 4.04Å; Y209-A320 HydrophobicContact CE1-CB 3.87Å; V210-A320 HydrophobicContact CG2-CB 3.89Å; V213-A320 HydrophobicContact CG2-CB 4.49Å; L307-A320 HydrophobicContact CD2-CB 4.27Å; A316-A320 PolarHBondContact O-N 2.84Å; A316-A320 VanDerWaalsContact O-N 3.07Å; V317-A320 CarbonylContact O-C 3.55Å; V317-A320 WeakPolarHBondContact O-CA 3.29Å; V317-A320 VanDerWaalsContact O-CB 3.26Å; V317-A320 WeakPolarHBondContact O-CB 3.25Å; V317-A320 PolarHBondContact O-N 3.34Å; A318-A320 VanDerWaalsContact C-N 3.31Å; A318-A320 PolarHBondContact O-N 3.32Å; A320-A322 PolarHBondContact O-N 3.45Å; A320-F323 PolarHBondContact O-N 2.88Å; A320-I324 WeakPolarHBondContact O-CG1 3.24Å; A320-I324 PolarHBondContact O-N 2.99Å
321	R	94.1	Very high	89.1	Confident	0 Å²	0	31.7 Å²	31.7	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-58.7	-46.1	173.2	-55.3	-161.5	178.6	107.1	0.5	111.2	Q148 L307 Y310 P311 P312 V317 A318 L319 F323 I324 V325	Q148-R321 HydrophobicContact CB-CB 4.28Å; Q148-R321 VanDerWaalsContact OE1-CB 3.27Å; Q148-R321 VanDerWaalsContact OE1-CD 3.26Å; L307-R321 HydrophobicContact CD1-CG 4.38Å; L307-R321 PolarHBondContact O-NH2 2.91Å; L307-R321 VanDerWaalsContact O-NH2 3.1Å; Y310-R321 PolarHBondContact O-NH2 3.42Å; P311-R321 PolarHBondContact O-NH2 3.26Å; P312-R321 PolarHBondContact O-NH1 3.42Å; V317-R321 HydrophobicContact CG1-CG 4.4Å; V317-R321 VanDerWaalsContact O-CG 3.28Å; V317-R321 WeakPolarHBondContact O-CG 3.28Å; V317-R321 PolarHBondContact O-N 2.91Å; A318-R321 WeakPolarHBondContact O-CB 3.44Å; A318-R321 PolarHBondContact O-N 3.42Å; L319-R321 VanDerWaalsContact C-N 3.35Å; R321-F323 PolarHBondContact O-N 3.31Å; R321-I324 PolarHBondContact O-N 3.5Å; R321-V325 WeakPolarHBondContact O-CG2 3.5Å; R321-V325 PolarHBondContact O-N 2.9Å
322	A	92.5	Very high	89.2	Confident	29 Å²	29	29.4 Å²	29.4	24%	0.24	17%	0.166	C	C	.	.	H	α-helix	trans	-60.9	-42.4	177.7	0	0	0	0	0	112.4	L152 A318 L319 A320 I324 V325 I326	L152-A322 HydrophobicContact CD2-CB 4.25Å; A318-A322 PolarHBondContact O-N 3.26Å; L319-A322 PolarHBondContact O-N 3.45Å; A320-A322 PolarHBondContact O-N 3.45Å; A322-I324 PolarHBondContact O-N 3.22Å; A322-V325 PolarHBondContact O-N 3.46Å; A322-I326 WeakPolarHBondContact O-CG1 3.39Å; A322-I326 PolarHBondContact O-N 3.43Å
323	F	92.3	Very high	89.2	Confident	56 Å²	56	29.3 Å²	29.3	25%	0.246	17%	0.165	C	C	.	.	H	α-helix	trans	-63.1	-39.7	174.9	-85.2	-64.3	0	0	0	112.9	L202 G206 Y209 L319 A320 R321 I326 C327	L202-F323 HydrophobicContact CD1-CE1 4.33Å; G206-F323 VanDerWaalsContact CA-CD1 3.48Å; Y209-F323 AromaticContact CD1-CD2 3.57Å; Y209-F323 HydrophobicContact CD1-CD2 3.57Å; Y209-F323 AromaticContact CD1-CE2 3.98Å; Y209-F323 HydrophobicContact CD1-CE2 3.98Å; Y209-F323 HydrophobicContact CD2-CE2 4.49Å; Y209-F323 HydrophobicContact CE1-CD2 4.13Å; Y209-F323 HydrophobicContact CE1-CE2 4.39Å; Y209-F323 AromaticContact CG-CD2 3.98Å; Y209-F323 HydrophobicContact CG-CD2 3.98Å; Y209-F323 HydrophobicContact CG-CE2 4.03Å; L319-F323 VanDerWaalsContact O-CD2 3.24Å; L319-F323 WeakPolarHBondContact O-CD2 3.43Å; L319-F323 PolarHBondContact O-N 2.96Å; A320-F323 PolarHBondContact O-N 2.88Å; R321-F323 PolarHBondContact O-N 3.31Å; F323-I326 PolarHBondContact O-N 2.92Å; F323-C327 WeakPolarHBondContact O-CB 3.45Å; F323-C327 PolarHBondContact O-N 3.04Å
324	I	92.3	Very high	89.1	Confident	1 Å²	1	25 Å²	25	1%	0.005	14%	0.142	C	C	.	.	H	α-helix	trans	-63.2	-43.9	174.1	-71.2	-61.9	0	0	0	111.2	L65 V144 Q148 V210 L307 A320 R321 A322 I326 C327 V328	L65-I324 HydrophobicContact CD1-CD1 4.33Å; L65-I324 HydrophobicContact CD1-CG1 4.35Å; L65-I324 HydrophobicContact CD1-CG2 3.78Å; L65-I324 HydrophobicContact CD2-CD1 3.92Å; L65-I324 HydrophobicContact CD2-CG1 4.08Å; L65-I324 HydrophobicContact CG-CD1 4.33Å; V144-I324 HydrophobicContact CG1-CG2 3.73Å; Q148-I324 HydrophobicContact CG-CG2 3.95Å; V210-I324 HydrophobicContact CG2-CD1 3.77Å; V210-I324 HydrophobicContact CG2-CG1 3.69Å; L307-I324 HydrophobicContact CD1-CG1 3.79Å; A320-I324 WeakPolarHBondContact O-CG1 3.24Å; A320-I324 PolarHBondContact O-N 2.99Å; R321-I324 PolarHBondContact O-N 3.5Å; A322-I324 PolarHBondContact O-N 3.22Å; I324-I326 VanDerWaalsContact C-N 3.3Å; I324-I326 PolarHBondContact O-N 3.19Å; I324-C327 WeakPolarHBondContact O-CB 3.4Å; I324-C327 PolarHBondContact O-N 3.5Å; I324-V328 HydrophobicContact CG2-CG2 4.24Å; I324-V328 WeakPolarHBondContact O-CG2 3.22Å; I324-V328 PolarHBondContact O-N 3.26Å
325	V	91.9	Very high	88.9	Confident	16 Å²	16	25.1 Å²	25.1	10%	0.097	14%	0.143	C	C	.	.	H	α-helix	trans	-57.4	-46.8	176	172.9	0	0	0	0	110.3	Q148 L149 R321 A322 C327 V328 V329	Q148-V325 HydrophobicContact CB-CG2 3.61Å; L149-V325 HydrophobicContact CD2-CG1 4.23Å; L149-V325 HydrophobicContact CD2-CG2 4.11Å; L149-V325 HydrophobicContact CG-CG1 4.41Å; L149-V325 HydrophobicContact CG-CG2 4.06Å; R321-V325 WeakPolarHBondContact O-CG2 3.5Å; R321-V325 PolarHBondContact O-N 2.9Å; A322-V325 PolarHBondContact O-N 3.46Å; V325-C327 PolarHBondContact O-N 2.99Å; V325-V328 PolarHBondContact O-N 3.43Å; V325-V329 HydrophobicContact CG1-CG2 4.17Å; V325-V329 VanDerWaalsContact O-CB 3.29Å; V325-V329 WeakPolarHBondContact O-CB 3.33Å; V325-V329 WeakPolarHBondContact O-CG2 3.31Å; V325-V329 PolarHBondContact O-N 3.07Å
326	I	88.6	Confident	88.7	Confident	67 Å²	67	19.7 Å²	19.7	34%	0.344	12%	0.115	S	C	.	.	H	α-helix	trans	-61.4	-45.3	177.1	-66	166.8	0	0	0	111.2	L202 A322 F323 I324 V328 T330	L202-I326 HydrophobicContact CD2-CG2 3.7Å; L202-I326 HydrophobicContact CG-CG2 4.19Å; A322-I326 WeakPolarHBondContact O-CG1 3.39Å; A322-I326 PolarHBondContact O-N 3.43Å; F323-I326 PolarHBondContact O-N 2.92Å; I324-I326 VanDerWaalsContact C-N 3.3Å; I324-I326 PolarHBondContact O-N 3.19Å; I326-V328 PolarHBondContact O-N 2.91Å; I326-T330 HydrophobicContact CG2-CG2 4.43Å; I326-T330 WeakPolarHBondContact O-CB 3.4Å; I326-T330 VanDerWaalsContact O-CG2 3.24Å; I326-T330 WeakPolarHBondContact O-CG2 3.2Å; I326-T330 PolarHBondContact O-N 3.05Å; I326-T330 PolarHBondContact O-OG1 2.92Å
327	C	88.5	Confident	88.1	Confident	0 Å²	0	19.8 Å²	19.8	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-56.7	-47.9	176.9	170.8	0	0	0	0	111.8	S203 F323 I324 V325 T330 S331	S203-C327 PolarHBondContact OG-SG 3.17Å; F323-C327 WeakPolarHBondContact O-CB 3.45Å; F323-C327 PolarHBondContact O-N 3.04Å; I324-C327 WeakPolarHBondContact O-CB 3.4Å; I324-C327 PolarHBondContact O-N 3.5Å; V325-C327 PolarHBondContact O-N 2.99Å; C327-T330 PolarHBondContact O-N 3.44Å; C327-T330 PolarHBondContact O-OG1 3.4Å; C327-S331 VanDerWaalsContact O-CB 3.3Å; C327-S331 WeakPolarHBondContact O-CB 3.33Å; C327-S331 PolarHBondContact O-N 3.01Å; C327-S331 PolarHBondContact O-OG 3.27Å
328	V	90.1	Very high	87.5	Confident	0 Å²	0	20.7 Å²	20.7	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-72.6	-42.6	-177.3	177.5	0	0	0	0	111.5	A62 F141 V144 I145 I324 V325 I326 T330 S331 Y332	A62-V328 HydrophobicContact CB-CG2 3.98Å; F141-V328 HydrophobicContact CB-CG1 3.38Å; F141-V328 HydrophobicContact CD1-CG1 3.7Å; F141-V328 HydrophobicContact CD2-CG1 3.94Å; F141-V328 HydrophobicContact CE1-CG1 4.42Å; F141-V328 HydrophobicContact CG-CG1 3.41Å; F141-V328 VanDerWaalsContact CG-CG1 3.41Å; V144-V328 HydrophobicContact CG1-CG2 4.04Å; I145-V328 HydrophobicContact CD1-CB 4.38Å; I145-V328 HydrophobicContact CD1-CG1 3.81Å; I145-V328 HydrophobicContact CG1-CB 4.17Å; I145-V328 HydrophobicContact CG1-CG1 3.84Å; I324-V328 HydrophobicContact CG2-CG2 4.24Å; I324-V328 WeakPolarHBondContact O-CG2 3.22Å; I324-V328 PolarHBondContact O-N 3.26Å; V325-V328 PolarHBondContact O-N 3.43Å; I326-V328 PolarHBondContact O-N 2.91Å; V328-T330 VanDerWaalsContact C-N 3.27Å; V328-T330 PolarHBondContact O-N 3.46Å; V328-S331 PolarHBondContact O-N 2.97Å; V328-S331 VanDerWaalsContact O-N 3.14Å; V328-Y332 PolarHBondContact O-N 3.43Å
329	V	87.6	Confident	87.2	Confident	11 Å²	11	20.1 Å²	20.1	7%	0.067	11%	0.111	C	C	.	.	H	α-helix	trans	-59.2	-39.2	175.3	165.7	0	0	0	0	111.4	I145 T179 V183 I184 L187 V325 P333	I145-V329 HydrophobicContact CD1-CG2 3.69Å; I145-V329 HydrophobicContact CG1-CG2 4.38Å; T179-V329 HydrophobicContact CG2-CG2 4.42Å; V183-V329 HydrophobicContact CG1-CG1 3.59Å; I184-V329 HydrophobicContact CD1-CG2 4.25Å; I184-V329 HydrophobicContact CG1-CG1 4.23Å; I184-V329 HydrophobicContact CG1-CG2 4.1Å; L187-V329 HydrophobicContact CD1-CG1 3.73Å; V325-V329 HydrophobicContact CG1-CG2 4.17Å; V325-V329 VanDerWaalsContact O-CB 3.29Å; V325-V329 WeakPolarHBondContact O-CB 3.33Å; V325-V329 WeakPolarHBondContact O-CG2 3.31Å; V325-V329 PolarHBondContact O-N 3.07Å; V329-P333 WeakPolarHBondContact O-CD 3.26Å
330	T	82.7	Confident	86.7	Confident	27 Å²	27	16.4 Å²	16.4	17%	0.166	9%	0.091	C	C	.	.	H	α-helix	trans	-77.8	-24.2	178.3	54.1	0	0	0	0	113.3	A199 I326 C327 V328	A199-T330 HydrophobicContact CB-CG2 3.75Å; I326-T330 HydrophobicContact CG2-CG2 4.43Å; I326-T330 WeakPolarHBondContact O-CB 3.4Å; I326-T330 VanDerWaalsContact O-CG2 3.24Å; I326-T330 WeakPolarHBondContact O-CG2 3.2Å; I326-T330 PolarHBondContact O-N 3.05Å; I326-T330 PolarHBondContact O-OG1 2.92Å; C327-T330 PolarHBondContact O-N 3.44Å; C327-T330 PolarHBondContact O-OG1 3.4Å; V328-T330 VanDerWaalsContact C-N 3.27Å; V328-T330 PolarHBondContact O-N 3.46Å
331	S	84.1	Confident	85.9	Confident	4 Å²	4	16.8 Å²	16.8	3%	0.028	9%	0.094	C	C	.	.	H	α-helix	trans	-84.8	-28.8	178.3	-61.3	0	0	0	0	113.3	C327 V328 I334 L335	C327-S331 VanDerWaalsContact O-CB 3.3Å; C327-S331 WeakPolarHBondContact O-CB 3.33Å; C327-S331 PolarHBondContact O-N 3.01Å; C327-S331 PolarHBondContact O-OG 3.27Å; V328-S331 PolarHBondContact O-N 2.97Å; V328-S331 VanDerWaalsContact O-N 3.14Å; S331-I334 WeakPolarHBondContact O-CB 3.42Å; S331-I334 WeakPolarHBondContact O-CG1 3.38Å; S331-I334 PolarHBondContact O-N 2.88Å; S331-L335 WeakPolarHBondContact O-CD1 3.4Å; S331-L335 PolarHBondContact O-N 3.38Å
332	Y	87.9	Confident	85.3	Confident	0 Å²	0	16.9 Å²	16.9	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-55.1	-48.9	-178.9	-175	-73.9	0	0	0	113.8	C138 F141 F142 I184 V328 I334 L335 H336 F374 T377	C138-Y332 HydrophobicContact CB-CD2 4.27Å; C138-Y332 HydrophobicContact CB-CE2 3.5Å; F141-Y332 HydrophobicContact CB-CD2 3.99Å; F141-Y332 AromaticContact CD2-CD2 3.99Å; F141-Y332 HydrophobicContact CD2-CD2 3.99Å; F141-Y332 HydrophobicContact CD2-CG 4.36Å; F142-Y332 HydrophobicContact CD2-CE2 4.12Å; F142-Y332 HydrophobicContact CE1-CE2 4.26Å; F142-Y332 AromaticContact CE2-CE2 3.61Å; F142-Y332 HydrophobicContact CE2-CE2 3.61Å; F142-Y332 AromaticContact CE2-CZ 3.84Å; F142-Y332 WeakPolarHBondContact CE2-OH 3.47Å; F142-Y332 AromaticContact CZ-CE2 3.68Å; F142-Y332 HydrophobicContact CZ-CE2 3.68Å; F142-Y332 AromaticContact CZ-CZ 3.78Å; I184-Y332 HydrophobicContact CG2-CD1 3.23Å; I184-Y332 HydrophobicContact CG2-CD2 4.25Å; I184-Y332 HydrophobicContact CG2-CE1 3.57Å; I184-Y332 HydrophobicContact CG2-CG 3.63Å; V328-Y332 PolarHBondContact O-N 3.43Å; Y332-I334 PolarHBondContact O-N 2.84Å; Y332-I334 VanDerWaalsContact O-N 3.16Å; Y332-L335 PolarHBondContact O-N 3.21Å; Y332-H336 HydrophobicContact CD1-CB 4.13Å; Y332-H336 HydrophobicContact CE1-CB 3.92Å; Y332-H336 VanDerWaalsContact O-CB 3.3Å; Y332-H336 WeakPolarHBondContact O-CB 3.46Å; Y332-H336 PolarHBondContact O-N 3.34Å; Y332-F374 HydrophobicContact CE1-CD2 4.37Å; Y332-T377 PolarHBondContact OH-OG1 3.41Å
333	P	82.2	Confident	85	Confident	25 Å²	25	17.5 Å²	17.5	16%	0.162	10%	0.095	C	C	.	.	H	α-helix	trans	-58.4	-32	-179.3	-27.2	36.2	0	0	0	113.6	L187 V329 F337	L187-P333 HydrophobicContact CB-CG 3.78Å; L187-P333 WeakPolarHBondContact O-CB 3.41Å; V329-P333 WeakPolarHBondContact O-CD 3.26Å; P333-F337 WeakPolarHBondContact O-CB 3.26Å; P333-F337 PolarHBondContact O-N 2.82Å
334	I	78.5	Confident	84.5	Confident	18 Å²	18	15.1 Å²	15.1	9%	0.092	9%	0.085	C	C	.	.	H	α-helix	trans	-66.7	-53.1	-178.9	-40.4	174.9	0	0	0	109.7	Q196 S331 Y332 H336 F337 C338	Q196-I334 HydrophobicContact CG-CD1 3.8Å; Q196-I334 HydrophobicContact CG-CG1 4.11Å; Q196-I334 VanDerWaalsContact OE1-CG1 3.31Å; S331-I334 WeakPolarHBondContact O-CB 3.42Å; S331-I334 WeakPolarHBondContact O-CG1 3.38Å; S331-I334 PolarHBondContact O-N 2.88Å; Y332-I334 PolarHBondContact O-N 2.84Å; Y332-I334 VanDerWaalsContact O-N 3.16Å; I334-H336 VanDerWaalsContact C-N 3.33Å; I334-H336 PolarHBondContact O-N 3.01Å; I334-F337 WeakPolarHBondContact O-CB 3.45Å; I334-F337 PolarHBondContact O-N 2.91Å; I334-C338 PolarHBondContact O-N 3.29Å; I334-C338 PolarHBondContact O-SG 3.27Å
335	L	82.3	Confident	83.8	Confident	26 Å²	26	15.3 Å²	15.3	14%	0.136	9%	0.086	C	C	.	.	H	α-helix	trans	-66.6	-39.7	179.9	-84.7	83.1	0	0	0	111.1	T137 F141 S331 Y332 F337 C338 G339	T137-L335 VanDerWaalsContact CB-CD2 3.42Å; T137-L335 HydrophobicContact CG2-CD2 3.23Å; F141-L335 HydrophobicContact CE2-CD1 4.08Å; F141-L335 HydrophobicContact CE2-CD2 4.33Å; F141-L335 HydrophobicContact CZ-CD1 4.27Å; F141-L335 HydrophobicContact CZ-CD2 4.37Å; S331-L335 WeakPolarHBondContact O-CD1 3.4Å; S331-L335 PolarHBondContact O-N 3.38Å; Y332-L335 PolarHBondContact O-N 3.21Å; L335-F337 VanDerWaalsContact C-N 3.3Å; L335-F337 PolarHBondContact O-N 3.22Å; L335-C338 PolarHBondContact O-N 3.43Å; L335-G339 PolarHBondContact O-N 2.93Å
336	H	84.6	Confident	83.3	Confident	2 Å²	2	16.7 Å²	16.7	1%	0.009	9%	0.093	C	C	.	.	H	α-helix	trans	-60.9	-40.3	174.4	-177.1	-77.9	0	0	0	111.6	Y332 I334 G339 R340 T370 W373	Y332-H336 HydrophobicContact CD1-CB 4.13Å; Y332-H336 HydrophobicContact CE1-CB 3.92Å; Y332-H336 VanDerWaalsContact O-CB 3.3Å; Y332-H336 WeakPolarHBondContact O-CB 3.46Å; Y332-H336 PolarHBondContact O-N 3.34Å; I334-H336 VanDerWaalsContact C-N 3.33Å; I334-H336 PolarHBondContact O-N 3.01Å; H336-G339 PolarHBondContact O-N 3.43Å; H336-R340 WeakPolarHBondContact O-CB 3.48Å; H336-R340 PolarHBondContact O-N 2.91Å; H336-T370 PolarHBondContact CE1-OG1 3.33Å; H336-W373 AromaticContact CD2-CD1 3.34Å; H336-W373 AromaticContact CD2-CG 3.95Å; H336-W373 AromaticContact CD2-NE1 3.8Å; H336-W373 AromaticContact NE2-CD1 3.59Å; H336-W373 AromaticContact NE2-CG 3.75Å
337	F	79.5	Confident	83	Confident	35 Å²	35	19.2 Å²	19.2	15%	0.154	10%	0.099	C	C	.	.	H	α-helix	trans	-61	-47.5	174.1	175.4	-87	0	0	0	111.5	Q27 I193 P333 I334 L335 R340 A341	Q27-F337 HydrophobicContact CB-CZ 4.29Å; Q27-F337 WeakPolarHBondContact O-CZ 3.25Å; I193-F337 HydrophobicContact CD1-CE1 4.35Å; P333-F337 WeakPolarHBondContact O-CB 3.26Å; P333-F337 PolarHBondContact O-N 2.82Å; I334-F337 WeakPolarHBondContact O-CB 3.45Å; I334-F337 PolarHBondContact O-N 2.91Å; L335-F337 VanDerWaalsContact C-N 3.3Å; L335-F337 PolarHBondContact O-N 3.22Å; F337-R340 VanDerWaalsContact CD2-NH2 3.25Å; F337-A341 VanDerWaalsContact O-CB 3.3Å; F337-A341 WeakPolarHBondContact O-CB 3.46Å; F337-A341 PolarHBondContact O-N 3.42Å
338	C	79.8	Confident	82.4	Confident	18 Å²	18	19.5 Å²	19.5	12%	0.122	10%	0.1	C	C	.	.	H	α-helix	trans	-63.2	-40.4	176.6	-67.9	0	0	0	0	112.7	T134 V255 I334 L335 A341 V342	T134-C338 HydrophobicContact CG2-CB 4.3Å; V255-C338 HydrophobicContact CG1-CB 4.43Å; I334-C338 PolarHBondContact O-N 3.29Å; I334-C338 PolarHBondContact O-SG 3.27Å; L335-C338 PolarHBondContact O-N 3.43Å; C338-A341 WeakPolarHBondContact O-CB 3.27Å; C338-A341 PolarHBondContact O-N 3.34Å; C338-V342 WeakPolarHBondContact O-CG2 3.23Å; C338-V342 PolarHBondContact O-N 2.9Å
339	G	84.5	Confident	81.7	Confident	0 Å²	0	21.7 Å²	21.7	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-64.7	-49.5	177	0	0	0	0	0	111.8	T134 L335 H336 A341 V342 V343	T134-G339 WeakPolarHBondContact OG1-CA 3.38Å; L335-G339 PolarHBondContact O-N 2.93Å; H336-G339 PolarHBondContact O-N 3.43Å; G339-A341 PolarHBondContact O-N 2.96Å; G339-V342 PolarHBondContact O-N 3.14Å; G339-V343 WeakPolarHBondContact O-CG2 3.47Å; G339-V343 PolarHBondContact O-N 3.01Å
340	R	81.9	Confident	81.2	Confident	10 Å²	10	30 Å²	30	4%	0.038	14%	0.143	C	C	.	.	H	α-helix	trans	-56.5	-39.3	173.2	-177.1	-178.6	67.6	-163.6	-4.6	111.3	H336 F337 V342 V343 E344 R366 Q369 T370	H336-R340 WeakPolarHBondContact O-CB 3.48Å; H336-R340 PolarHBondContact O-N 2.91Å; F337-R340 VanDerWaalsContact CD2-NH2 3.25Å; R340-V342 VanDerWaalsContact C-N 3.25Å; R340-V342 PolarHBondContact O-N 3.47Å; R340-V343 PolarHBondContact O-N 3.14Å; R340-E344 VanDerWaalsContact O-CB 3.25Å; R340-E344 WeakPolarHBondContact O-CB 3.21Å; R340-E344 PolarHBondContact O-N 2.98Å; R340-R366 VanDerWaalsContact NH1-CG 3.31Å; R340-Q369 HydrophobicContact CG-CB 4.46Å; R340-T370 PolarHBondContact NH1-OG1 3.44Å
341	A	78	Confident	80.7	Confident	8 Å²	8	32.4 Å²	32.4	7%	0.066	15%	0.153	C	C	.	.	H	α-helix	trans	-55.7	-46.5	-177.1	0	0	0	0	0	112.2	Q27 F337 C338 G339 G345	Q27-A341 PolarHBondContact NE2-O 2.88Å; Q27-A341 PolarHBondContact OE1-O 2.92Å; F337-A341 VanDerWaalsContact O-CB 3.3Å; F337-A341 WeakPolarHBondContact O-CB 3.46Å; F337-A341 PolarHBondContact O-N 3.42Å; C338-A341 WeakPolarHBondContact O-CB 3.27Å; C338-A341 PolarHBondContact O-N 3.34Å; G339-A341 PolarHBondContact O-N 2.96Å; A341-G345 PolarHBondContact O-N 3.15Å
342	V	82.3	Confident	79.7	Confident	2 Å²	2	35.1 Å²	35.1	1%	0.012	18%	0.182	C	C	.	.	H	α-helix	trans	-76.7	-40.9	-177.5	174.5	0	0	0	0	112.6	Q111 E127 I130 A131 C338 G339 R340 E344 G345 L346	Q111-V342 HydrophobicContact CG-CG2 4.36Å; E127-V342 VanDerWaalsContact C-CG1 3.48Å; E127-V342 VanDerWaalsContact CA-CG1 3.42Å; E127-V342 HydrophobicContact CB-CG1 3.44Å; E127-V342 VanDerWaalsContact CB-CG1 3.44Å; E127-V342 HydrophobicContact CG-CG1 3.8Å; E127-V342 WeakPolarHBondContact O-CG1 3.41Å; I130-V342 HydrophobicContact CB-CG2 4.22Å; I130-V342 HydrophobicContact CG2-CG2 3.8Å; A131-V342 HydrophobicContact CB-CG1 4.39Å; C338-V342 WeakPolarHBondContact O-CG2 3.23Å; C338-V342 PolarHBondContact O-N 2.9Å; G339-V342 PolarHBondContact O-N 3.14Å; R340-V342 VanDerWaalsContact C-N 3.25Å; R340-V342 PolarHBondContact O-N 3.47Å; V342-E344 VanDerWaalsContact C-N 3.27Å; V342-E344 PolarHBondContact O-N 3.48Å; V342-G345 PolarHBondContact O-N 2.69Å; V342-L346 HydrophobicContact CG1-CD1 4.22Å; V342-L346 WeakPolarHBondContact O-CG 3.24Å; V342-L346 PolarHBondContact O-N 2.88Å
343	V	85.6	Confident	78.3	Confident	41 Å²	41	37.5 Å²	37.5	25%	0.248	19%	0.193	C	C	.	.	H	α-helix	trans	-58.5	-43.2	175	170.7	0	0	0	0	111.2	A131 G339 R340 L346 W347 W373	A131-V343 HydrophobicContact CB-CG2 4.43Å; G339-V343 WeakPolarHBondContact O-CG2 3.47Å; G339-V343 PolarHBondContact O-N 3.01Å; R340-V343 PolarHBondContact O-N 3.14Å; V343-L346 PolarHBondContact O-N 3.35Å; V343-W347 VanDerWaalsContact O-CB 3.29Å; V343-W347 WeakPolarHBondContact O-CB 3.37Å; V343-W347 PolarHBondContact O-N 3.06Å; V343-W373 HydrophobicContact CG2-CE3 4.1Å; V343-W373 HydrophobicContact CG2-CH2 4.35Å; V343-W373 HydrophobicContact CG2-CZ3 3.46Å; V343-W373 VanDerWaalsContact CG2-CZ3 3.46Å
344	E	82	Confident	76.9	Confident	7 Å²	7	43.5 Å²	43.5	3%	0.033	22%	0.219	C	C	.	.	H	α-helix	trans	-63.3	-43.2	177	177	67.6	-177.2	0	0	111.6	Q27 R340 V342 W347 L348 R365 Q369	Q27-E344 VanDerWaalsContact NE2-CG 3.29Å; R340-E344 VanDerWaalsContact O-CB 3.25Å; R340-E344 WeakPolarHBondContact O-CB 3.21Å; R340-E344 PolarHBondContact O-N 2.98Å; V342-E344 VanDerWaalsContact C-N 3.27Å; V342-E344 PolarHBondContact O-N 3.48Å; E344-W347 PolarHBondContact O-N 3.49Å; E344-L348 HydrophobicContact CG-CD1 4.18Å; E344-L348 WeakPolarHBondContact O-CB 3.19Å; E344-L348 VanDerWaalsContact O-CG 3.29Å; E344-L348 WeakPolarHBondContact O-CG 3.29Å; E344-L348 PolarHBondContact O-N 2.62Å; E344-R365 IonicContact OE1-CZ 2.63Å; E344-R365 IonicContact OE1-NE 2.62Å; E344-R365 PolarHBondContact OE1-NE 3.35Å; E344-R365 IonicContact OE1-NH2 3.85Å; E344-R365 PolarHBondContact OE1-NH2 3.12Å; E344-R365 WeakPolarHBondContact OE2-CD 3.13Å; E344-R365 IonicContact OE2-CZ 3.31Å; E344-R365 IonicContact OE2-NE 2.99Å; E344-R365 PolarHBondContact OE2-NE 3.17Å; E344-Q369 PolarHBondContact OE2-NE2 3.43Å; E344-Q369 PolarHBondContact OE2-OE1 2.88Å
345	G	77.9	Confident	75.9	Confident	4 Å²	4	45.7 Å²	45.7	4%	0.041	23%	0.233	C	C	.	.	H	α-helix	trans	-60	-45.7	174.4	0	0	0	0	0	112.8	A341 V342 R349	A341-G345 PolarHBondContact O-N 3.15Å; V342-G345 PolarHBondContact O-N 2.69Å; G345-R349 WeakPolarHBondContact O-CB 3.01Å; G345-R349 WeakPolarHBondContact O-CD 3.33Å; G345-R349 WeakPolarHBondContact O-CG 3.34Å; G345-R349 PolarHBondContact O-N 3.42Å; G345-R349 VanDerWaalsContact O-N 3.1Å
346	L	81.7	Confident	74.5	Confident	46 Å²	46	52.3 Å²	52.3	24%	0.241	26%	0.263	C	S	.	.	H	α-helix	trans	-61.7	-44.7	175.5	-73	170.3	0	0	0	111.7	V124 E127 M128 V342 V343 R349 F350	V124-L346 HydrophobicContact CG1-CD2 4.18Å; E127-L346 HydrophobicContact CB-CD1 4.2Å; E127-L346 HydrophobicContact CB-CD2 3.93Å; E127-L346 HydrophobicContact CB-CG 4.06Å; E127-L346 VanDerWaalsContact OE2-CD2 3.29Å; E127-L346 WeakPolarHBondContact OE2-CD2 3.17Å; M128-L346 HydrophobicContact CG-CD1 4.36Å; V342-L346 HydrophobicContact CG1-CD1 4.22Å; V342-L346 WeakPolarHBondContact O-CG 3.24Å; V342-L346 PolarHBondContact O-N 2.88Å; V343-L346 PolarHBondContact O-N 3.35Å; L346-R349 PolarHBondContact O-N 2.79Å; L346-F350 WeakPolarHBondContact O-CB 3.3Å; L346-F350 PolarHBondContact O-N 3.06Å
347	W	81.2	Confident	73.3	Confident	120 Å²	120	54.9 Å²	54.9	46%	0.455	28%	0.279	S	S	.	.	H	α-helix	trans	-61.7	-48.1	179.7	-177.4	-89.1	0	0	0	112.1	V343 E344 R349 F350 Q351	V343-W347 VanDerWaalsContact O-CB 3.29Å; V343-W347 WeakPolarHBondContact O-CB 3.37Å; V343-W347 PolarHBondContact O-N 3.06Å; E344-W347 PolarHBondContact O-N 3.49Å; W347-R349 VanDerWaalsContact C-N 3.32Å; W347-R349 PolarHBondContact O-N 3.02Å; W347-F350 PolarHBondContact O-N 3.22Å; W347-Q351 HydrophobicContact CZ2-CG 4.3Å; W347-Q351 PolarHBondContact O-N 3.16Å
348	L	77.1	Confident	72.4	Confident	5 Å²	5	53.4 Å²	53.4	3%	0.026	27%	0.272	C	S	.	.	H	α-helix	trans	-62.2	-39.8	178.7	-72	173.9	0	0	0	112	A23 L26 E344 F350 Q351 G352 C358	A23-L348 HydrophobicContact CB-CD1 4.13Å; L26-L348 HydrophobicContact CD1-CD1 4.27Å; E344-L348 HydrophobicContact CG-CD1 4.18Å; E344-L348 WeakPolarHBondContact O-CB 3.19Å; E344-L348 VanDerWaalsContact O-CG 3.29Å; E344-L348 WeakPolarHBondContact O-CG 3.29Å; E344-L348 PolarHBondContact O-N 2.62Å; L348-F350 VanDerWaalsContact C-N 3.34Å; L348-Q351 PolarHBondContact O-N 3.18Å; L348-G352 PolarHBondContact O-N 3.14Å; L348-G352 VanDerWaalsContact O-N 3.07Å; L348-C358 HydrophobicContact CD2-CB 4.15Å; L348-C358 WeakPolarHBondContact CD2-SG 3.39Å
349	R	74.1	Confident	71.6	Confident	47 Å²	47	56.5 Å²	56.5	18%	0.177	29%	0.291	C	S	.	.	H	α-helix	trans	-66.8	-35.1	176.6	-72.6	170.3	-179.2	-172.3	7	112.7	S19 E112 R115 E127 G345 L346 W347	S19-R349 VanDerWaalsContact CB-CG 3.47Å; E112-R349 IonicContact OE1-CZ 2.82Å; E112-R349 IonicContact OE1-NH2 3.04Å; E112-R349 PolarHBondContact OE1-NH2 3.1Å; E112-R349 IonicContact OE2-NH2 2.9Å; E112-R349 PolarHBondContact OE2-NH2 2.98Å; R115-R349 VanDerWaalsContact CD-NH2 3.32Å; R115-R349 VanDerWaalsContact CZ-NH1 3.33Å; E127-R349 IonicContact OE1-CZ 3.53Å; E127-R349 IonicContact OE1-NH1 2.72Å; E127-R349 PolarHBondContact OE1-NH1 3.48Å; E127-R349 IonicContact OE1-NH2 3.9Å; E127-R349 PolarHBondContact OE1-NH2 2.93Å; E127-R349 IonicContact OE2-CZ 2.67Å; E127-R349 IonicContact OE2-NH1 2.63Å; E127-R349 PolarHBondContact OE2-NH1 2.89Å; G345-R349 WeakPolarHBondContact O-CB 3.01Å; G345-R349 WeakPolarHBondContact O-CD 3.33Å; G345-R349 WeakPolarHBondContact O-CG 3.34Å; G345-R349 PolarHBondContact O-N 3.42Å; G345-R349 VanDerWaalsContact O-N 3.1Å; L346-R349 PolarHBondContact O-N 2.79Å; W347-R349 VanDerWaalsContact C-N 3.32Å; W347-R349 PolarHBondContact O-N 3.02Å
350	F	78.3	Confident	70.6	Confident	184 Å²	184	66.1 Å²	66.1	81%	0.807	33%	0.327	S	S	*	.	H	α-helix	trans	-72.4	-39.2	177.3	-169.5	-97.3	0	0	0	112.3	L346 W347 L348	L346-F350 WeakPolarHBondContact O-CB 3.3Å; L346-F350 PolarHBondContact O-N 3.06Å; W347-F350 PolarHBondContact O-N 3.22Å; L348-F350 VanDerWaalsContact C-N 3.34Å
351	Q	72.1	Confident	69.9	Low	78 Å²	78	72 Å²	72	36%	0.364	35%	0.349	S	S	.	.	H	α-helix	trans	-83.2	-25.3	-176.4	-70.5	-159.3	-51.7	0	0	114.8	W347 L348 E353	W347-Q351 HydrophobicContact CZ2-CG 4.3Å; W347-Q351 PolarHBondContact O-N 3.16Å; L348-Q351 PolarHBondContact O-N 3.18Å; Q351-E353 HydrophobicContact CB-CG 4.11Å; Q351-E353 PolarHBondContact O-N 3.32Å; Q351-E353 VanDerWaalsContact O-N 3.12Å
352	G	63.3	Low	69.7	Low	61 Å²	61	72.6 Å²	72.6	63%	0.629	35%	0.35	S	S	*	.			trans	60.4	21.2	179.9	0	0	0	0	0	114.9	L348	L348-G352 PolarHBondContact O-N 3.14Å; L348-G352 VanDerWaalsContact O-N 3.07Å
353	E	58.3	Low	69.3	Low	50 Å²	50	81.3 Å²	81.3	23%	0.234	38%	0.383	C	S	.	.			trans	-68.9	156.9	-175.1	-78.8	-173.3	176	0	0	113.3	R22 Q351	R22-E353 PolarHBondContact NH1-O 3.22Å; Q351-E353 HydrophobicContact CB-CG 4.11Å; Q351-E353 PolarHBondContact O-N 3.32Å; Q351-E353 VanDerWaalsContact O-N 3.12Å
354	Q	52.3	Low	68.9	Low	151 Å²	151	89.4 Å²	89.4	71%	0.706	41%	0.409	S	S	*	.			trans	-71.7	144.2	175.4	-66.1	-127.7	-8.2	0	0	112.6	E356 V357 C358	Q354-E356 VanDerWaalsContact C-N 3.34Å; Q354-E356 PolarHBondContact O-N 3.4Å; Q354-V357 PolarHBondContact O-N 2.78Å; Q354-C358 PolarHBondContact O-N 3.22Å
355	V	56.7	Low	68.8	Low	64 Å²	64	90.4 Å²	90.4	39%	0.388	41%	0.413	S	S	.	.	H	α-helix	trans	-51.8	-44.8	-173.2	-174.7	0	0	0	0	113.3	R22 V357 C358 V359	R22-V355 HydrophobicContact CG-CG2 4.23Å; R22-V355 VanDerWaalsContact NH2-CG2 3.3Å; V355-V357 VanDerWaalsContact C-N 3.34Å; V355-V357 PolarHBondContact O-N 3.4Å; V355-C358 WeakPolarHBondContact O-CB 3.33Å; V355-C358 PolarHBondContact O-N 2.93Å; V355-C358 VanDerWaalsContact O-N 3.12Å; V355-V359 HydrophobicContact CG1-CG2 4.29Å; V355-V359 WeakPolarHBondContact O-CG2 2.95Å; V355-V359 PolarHBondContact O-N 2.9Å
356	E	53.9	Low	68.7	Low	166 Å²	166	91 Å²	91	78%	0.776	41%	0.414	S	S	*	.	H	α-helix	trans	-64.1	-35.8	-174.8	-103.8	169.3	143.1	0	0	113.4	Q354 R360	Q354-E356 VanDerWaalsContact C-N 3.34Å; Q354-E356 PolarHBondContact O-N 3.4Å; E356-R360 PolarHBondContact O-N 2.82Å
357	V	60	Low	68.7	Low	56 Å²	56	92.4 Å²	92.4	34%	0.339	42%	0.421	S	S	.	.	H	α-helix	trans	-72.1	-36.5	175.8	-177.6	0	0	0	0	110.3	Q354 V355 R360 R361	Q354-V357 PolarHBondContact O-N 2.78Å; V355-V357 VanDerWaalsContact C-N 3.34Å; V355-V357 PolarHBondContact O-N 3.4Å; V357-R360 PolarHBondContact O-N 2.91Å; V357-R361 PolarHBondContact O-N 3.24Å
358	C	60.3	Low	69	Low	3 Å²	3	92 Å²	92	2%	0.02	43%	0.427	C	S	.	.	H	α-helix	trans	-63.9	-39.7	177.2	-69.9	0	0	0	0	112.9	L348 Q354 V355 E362 R365	L348-C358 HydrophobicContact CD2-CB 4.15Å; L348-C358 WeakPolarHBondContact CD2-SG 3.39Å; Q354-C358 PolarHBondContact O-N 3.22Å; V355-C358 WeakPolarHBondContact O-CB 3.33Å; V355-C358 PolarHBondContact O-N 2.93Å; V355-C358 VanDerWaalsContact O-N 3.12Å; C358-E362 WeakPolarHBondContact O-CA 2.94Å; C358-E362 WeakPolarHBondContact O-CB 3.14Å; C358-E362 PolarHBondContact O-N 2.86Å; C358-R365 PolarHBondContact O-NH2 3.44Å
359	V	62.5	Low	69.4	Low	83 Å²	83	93.2 Å²	93.2	50%	0.503	43%	0.433	S	S	.	.	H	α-helix	trans	-68.9	-41.4	177.7	176.2	0	0	0	0	111.4	L26 V355 R361 E362	L26-V359 HydrophobicContact CD2-CG2 4.06Å; V355-V359 HydrophobicContact CG1-CG2 4.29Å; V355-V359 WeakPolarHBondContact O-CG2 2.95Å; V355-V359 PolarHBondContact O-N 2.9Å; V359-R361 PolarHBondContact O-N 3.26Å; V359-E362 WeakPolarHBondContact O-CB 3.35Å; V359-E362 PolarHBondContact O-N 3.43Å
360	R	62.6	Low	69.9	Low	203 Å²	203	91.2 Å²	91.2	77%	0.766	43%	0.426	S	S	*	.	H	α-helix	trans	-67.4	-34.1	179.8	-169	173.5	68.2	156.9	-1.1	113.1	E356 V357	E356-R360 PolarHBondContact O-N 2.82Å; V357-R360 PolarHBondContact O-N 2.91Å
361	R	68.7	Low	70.4	Confident	134 Å²	134	86.1 Å²	86.1	51%	0.506	41%	0.406	S	S	.	.	H	α-helix	trans	-91.4	-10.1	178.8	-72.7	-179.1	172.7	175.9	-1.9	114.1	V357 V359 R363 R364 R365	V357-R361 PolarHBondContact O-N 3.24Å; V359-R361 PolarHBondContact O-N 3.26Å; R361-R363 PolarHBondContact O-N 3.09Å; R361-R364 PolarHBondContact O-N 3.3Å; R361-R364 VanDerWaalsContact O-N 3.12Å; R361-R365 WeakPolarHBondContact O-CB 3.44Å; R361-R365 PolarHBondContact O-N 3.3Å
362	E	73	Confident	71.4	Confident	19 Å²	19	86.2 Å²	86.2	9%	0.089	41%	0.412	C	S	.	.	H	α-helix	trans	-42.4	-60	-178.9	-170.8	-69.1	114.3	0	0	112.5	L26 K191 C358 V359 R364 R365 R366	L26-E362 HydrophobicContact CB-CG 4.24Å; L26-E362 HydrophobicContact CD1-CG 4.15Å; L26-E362 HydrophobicContact CD2-CB 4.42Å; L26-E362 HydrophobicContact CD2-CG 3.65Å; L26-E362 HydrophobicContact CG-CG 4.21Å; K191-E362 IonicContact NZ-OE2 3.73Å; K191-E362 PolarHBondContact NZ-OE2 2.93Å; C358-E362 WeakPolarHBondContact O-CA 2.94Å; C358-E362 WeakPolarHBondContact O-CB 3.14Å; C358-E362 PolarHBondContact O-N 2.86Å; V359-E362 WeakPolarHBondContact O-CB 3.35Å; V359-E362 PolarHBondContact O-N 3.43Å; E362-R364 VanDerWaalsContact C-N 3.33Å; E362-R364 PolarHBondContact O-N 3.02Å; E362-R365 PolarHBondContact O-N 3.44Å; E362-R366 VanDerWaalsContact O-CB 3.26Å; E362-R366 WeakPolarHBondContact O-CB 3.39Å; E362-R366 PolarHBondContact O-N 3.26Å; E362-R366 IonicContact OE1-CZ 3.3Å; E362-R366 IonicContact OE1-NE 3.77Å; E362-R366 PolarHBondContact OE1-NE 3.04Å; E362-R366 IonicContact OE1-NH2 3.73Å; E362-R366 PolarHBondContact OE1-NH2 3.28Å; E362-R366 IonicContact OE2-CZ 3.19Å; E362-R366 IonicContact OE2-NE 2.82Å; E362-R366 IonicContact OE2-NH2 2.72Å; E362-R366 PolarHBondContact OE2-NH2 3.39Å
363	R	73.3	Confident	72.7	Confident	185 Å²	185	84.7 Å²	84.7	70%	0.698	39%	0.387	S	S	*	.	H	α-helix	trans	-60.5	-41.5	-175.8	-171.9	179.5	-177.3	-144.2	1	112.3	R361 I367	R361-R363 PolarHBondContact O-N 3.09Å; R363-I367 HydrophobicContact CG-CD1 4.04Å; R363-I367 WeakPolarHBondContact O-CD1 3.5Å; R363-I367 VanDerWaalsContact O-CG1 3.24Å; R363-I367 WeakPolarHBondContact O-CG1 3.45Å; R363-I367 PolarHBondContact O-N 2.96Å
364	R	78.3	Confident	74.3	Confident	212 Å²	212	82.6 Å²	82.6	80%	0.8	38%	0.377	S	S	*	.	H	α-helix	trans	-70.6	-42	-179.6	-170.8	177.1	-179.9	-176	-0.5	111.2	R361 E362 I367 L368	R361-R364 PolarHBondContact O-N 3.3Å; R361-R364 VanDerWaalsContact O-N 3.12Å; E362-R364 VanDerWaalsContact C-N 3.33Å; E362-R364 PolarHBondContact O-N 3.02Å; R364-I367 PolarHBondContact O-N 2.98Å; R364-L368 VanDerWaalsContact O-CB 3.32Å; R364-L368 WeakPolarHBondContact O-CB 3.5Å; R364-L368 PolarHBondContact O-N 3.04Å
365	R	78.4	Confident	76.3	Confident	27 Å²	27	79 Å²	79	10%	0.102	37%	0.366	C	S	.	.	H	α-helix	trans	-64.2	-44.7	176.2	-178.1	169.1	61.6	-122.7	-10.7	111.1	E344 C358 R361 E362 I367 L368 Q369	E344-R365 IonicContact OE1-CZ 2.63Å; E344-R365 IonicContact OE1-NE 2.62Å; E344-R365 PolarHBondContact OE1-NE 3.35Å; E344-R365 IonicContact OE1-NH2 3.85Å; E344-R365 PolarHBondContact OE1-NH2 3.12Å; E344-R365 WeakPolarHBondContact OE2-CD 3.13Å; E344-R365 IonicContact OE2-CZ 3.31Å; E344-R365 IonicContact OE2-NE 2.99Å; E344-R365 PolarHBondContact OE2-NE 3.17Å; C358-R365 PolarHBondContact O-NH2 3.44Å; R361-R365 WeakPolarHBondContact O-CB 3.44Å; R361-R365 PolarHBondContact O-N 3.3Å; E362-R365 PolarHBondContact O-N 3.44Å; R365-I367 PolarHBondContact O-N 3.37Å; R365-L368 PolarHBondContact O-N 2.84Å; R365-Q369 HydrophobicContact CG-CG 4.34Å; R365-Q369 WeakPolarHBondContact O-CB 3.35Å; R365-Q369 VanDerWaalsContact O-CG 3.32Å; R365-Q369 WeakPolarHBondContact O-CG 3.5Å; R365-Q369 PolarHBondContact O-N 3.42Å
366	R	77.4	Confident	78.1	Confident	16 Å²	16	79 Å²	79	6%	0.06	37%	0.365	C	S	.	.	H	α-helix	trans	-57	-50.5	174.9	-174.3	-167	-61.7	-127.3	0.1	111.8	L26 R340 E362 T370	L26-R366 PolarHBondContact O-NH2 3.45Å; R340-R366 VanDerWaalsContact NH1-CG 3.31Å; E362-R366 VanDerWaalsContact O-CB 3.26Å; E362-R366 WeakPolarHBondContact O-CB 3.39Å; E362-R366 PolarHBondContact O-N 3.26Å; E362-R366 IonicContact OE1-CZ 3.3Å; E362-R366 IonicContact OE1-NE 3.77Å; E362-R366 PolarHBondContact OE1-NE 3.04Å; E362-R366 IonicContact OE1-NH2 3.73Å; E362-R366 PolarHBondContact OE1-NH2 3.28Å; E362-R366 IonicContact OE2-CZ 3.19Å; E362-R366 IonicContact OE2-NE 2.82Å; E362-R366 IonicContact OE2-NH2 2.72Å; E362-R366 PolarHBondContact OE2-NH2 3.39Å; R366-T370 WeakPolarHBondContact O-CB 3.33Å; R366-T370 PolarHBondContact O-N 3.28Å; R366-T370 PolarHBondContact O-OG1 2.63Å; R366-T370 VanDerWaalsContact O-OG1 3.1Å
367	I	81.9	Confident	80	Confident	77 Å²	77	71 Å²	71	40%	0.395	33%	0.328	S	S	.	.	H	α-helix	trans	-63.1	-44.6	179.2	-69.2	167.2	0	0	0	110.3	R363 R364 R365 T370 L371	R363-I367 HydrophobicContact CG-CD1 4.04Å; R363-I367 WeakPolarHBondContact O-CD1 3.5Å; R363-I367 VanDerWaalsContact O-CG1 3.24Å; R363-I367 WeakPolarHBondContact O-CG1 3.45Å; R363-I367 PolarHBondContact O-N 2.96Å; R364-I367 PolarHBondContact O-N 2.98Å; R365-I367 PolarHBondContact O-N 3.37Å; I367-T370 PolarHBondContact O-N 3.16Å; I367-L371 HydrophobicContact CG2-CD1 3.72Å; I367-L371 HydrophobicContact CG2-CG 4.25Å; I367-L371 WeakPolarHBondContact O-CB 3.32Å; I367-L371 VanDerWaalsContact O-CG 3.29Å; I367-L371 WeakPolarHBondContact O-CG 3.19Å; I367-L371 PolarHBondContact O-N 3.47Å
368	L	86.8	Confident	81.6	Confident	111 Å²	111	69.2 Å²	69.2	58%	0.581	32%	0.316	S	S	*	.	H	α-helix	trans	-62.1	-49	179.1	-177.9	66.2	0	0	0	111.8	R364 R365 T370 L371 V372	R364-L368 VanDerWaalsContact O-CB 3.32Å; R364-L368 WeakPolarHBondContact O-CB 3.5Å; R364-L368 PolarHBondContact O-N 3.04Å; R365-L368 PolarHBondContact O-N 2.84Å; L368-T370 VanDerWaalsContact C-N 3.35Å; L368-T370 PolarHBondContact O-N 2.86Å; L368-L371 PolarHBondContact O-N 2.8Å; L368-V372 HydrophobicContact CD1-CG2 4Å; L368-V372 HydrophobicContact CG-CG2 4.3Å; L368-V372 WeakPolarHBondContact O-CB 3.41Å; L368-V372 VanDerWaalsContact O-CG2 3.26Å; L368-V372 WeakPolarHBondContact O-CG2 3.21Å; L368-V372 PolarHBondContact O-N 3.48Å
369	Q	85.3	Confident	83.2	Confident	31 Å²	31	72.2 Å²	72.2	15%	0.145	34%	0.335	C	S	.	.	H	α-helix	trans	-59.2	-46.1	176.7	-75.2	167.6	-12.5	0	0	111.2	R340 E344 R365 L371 W373	R340-Q369 HydrophobicContact CG-CB 4.46Å; E344-Q369 PolarHBondContact OE2-NE2 3.43Å; E344-Q369 PolarHBondContact OE2-OE1 2.88Å; R365-Q369 HydrophobicContact CG-CG 4.34Å; R365-Q369 WeakPolarHBondContact O-CB 3.35Å; R365-Q369 VanDerWaalsContact O-CG 3.32Å; R365-Q369 WeakPolarHBondContact O-CG 3.5Å; R365-Q369 PolarHBondContact O-N 3.42Å; Q369-L371 PolarHBondContact O-N 2.89Å; Q369-W373 WeakPolarHBondContact O-CB 3.49Å; Q369-W373 PolarHBondContact O-N 3.48Å
370	T	85.1	Confident	84.6	Confident	5 Å²	5	71.4 Å²	71.4	3%	0.031	33%	0.327	C	S	.	.	H	α-helix	trans	-59.1	-47.6	176.5	-70.8	0	0	0	0	111.6	H336 R340 R366 I367 L368 F374	H336-T370 PolarHBondContact CE1-OG1 3.33Å; R340-T370 PolarHBondContact NH1-OG1 3.44Å; R366-T370 WeakPolarHBondContact O-CB 3.33Å; R366-T370 PolarHBondContact O-N 3.28Å; R366-T370 PolarHBondContact O-OG1 2.63Å; R366-T370 VanDerWaalsContact O-OG1 3.1Å; I367-T370 PolarHBondContact O-N 3.16Å; L368-T370 VanDerWaalsContact C-N 3.35Å; L368-T370 PolarHBondContact O-N 2.86Å; T370-F374 WeakPolarHBondContact O-CB 3.45Å; T370-F374 PolarHBondContact O-N 2.99Å
371	L	88.8	Confident	86	Confident	76 Å²	76	61.7 Å²	61.7	40%	0.398	29%	0.291	S	S	.	.	H	α-helix	trans	-67.9	-44.9	-178.4	-72.2	174	0	0	0	112.1	L185 I367 L368 Q369 F374 V375	L185-L371 HydrophobicContact CD1-CD2 4.09Å; L185-L371 HydrophobicContact CD2-CD2 4.43Å; I367-L371 HydrophobicContact CG2-CD1 3.72Å; I367-L371 HydrophobicContact CG2-CG 4.25Å; I367-L371 WeakPolarHBondContact O-CB 3.32Å; I367-L371 VanDerWaalsContact O-CG 3.29Å; I367-L371 WeakPolarHBondContact O-CG 3.19Å; I367-L371 PolarHBondContact O-N 3.47Å; L368-L371 PolarHBondContact O-N 2.8Å; Q369-L371 PolarHBondContact O-N 2.89Å; L371-F374 PolarHBondContact O-N 3.49Å; L371-V375 WeakPolarHBondContact O-CB 3.34Å; L371-V375 VanDerWaalsContact O-CG2 3.23Å; L371-V375 WeakPolarHBondContact O-CG2 3.48Å; L371-V375 PolarHBondContact O-N 3.06Å
372	V	91.8	Very high	87	Confident	80 Å²	80	57.1 Å²	57.1	49%	0.485	28%	0.276	S	S	.	.	H	α-helix	trans	-62.8	-48.8	178.5	171.3	0	0	0	0	110.1	L368 F374 V375 V376	L368-V372 HydrophobicContact CD1-CG2 4Å; L368-V372 HydrophobicContact CG-CG2 4.3Å; L368-V372 WeakPolarHBondContact O-CB 3.41Å; L368-V372 VanDerWaalsContact O-CG2 3.26Å; L368-V372 WeakPolarHBondContact O-CG2 3.21Å; L368-V372 PolarHBondContact O-N 3.48Å; V372-F374 PolarHBondContact O-N 3.45Å; V372-V375 PolarHBondContact O-N 2.96Å; V372-V376 HydrophobicContact CG1-CG2 4.32Å; V372-V376 WeakPolarHBondContact O-CB 3.41Å; V372-V376 WeakPolarHBondContact O-CG2 3.34Å; V372-V376 PolarHBondContact O-N 3.01Å
373	W	92	Very high	87.8	Confident	30 Å²	30	63.7 Å²	63.7	11%	0.114	31%	0.305	C	S	.	.	H	α-helix	trans	-57.1	-51.6	177.6	-173	-70.7	0	0	0	111.2	A131 T134 F135 H336 V343 Q369 V375 V376 T377	A131-W373 VanDerWaalsContact O-CH2 3.29Å; A131-W373 WeakPolarHBondContact O-CH2 3.44Å; T134-W373 WeakPolarHBondContact OG1-CZ2 3.29Å; F135-W373 VanDerWaalsContact CA-CZ2 3.42Å; F135-W373 HydrophobicContact CB-CH2 3.79Å; F135-W373 HydrophobicContact CB-CZ2 3.57Å; F135-W373 AromaticContact CD2-CD2 4Å; F135-W373 HydrophobicContact CD2-CD2 4Å; F135-W373 AromaticContact CD2-CE2 3.83Å; F135-W373 HydrophobicContact CD2-CE3 4.26Å; F135-W373 HydrophobicContact CD2-CH2 4.35Å; F135-W373 HydrophobicContact CD2-CZ2 4.08Å; F135-W373 HydrophobicContact CD2-CZ3 4.39Å; F135-W373 HydrophobicContact CG-CZ2 4.34Å; H336-W373 AromaticContact CD2-CD1 3.34Å; H336-W373 AromaticContact CD2-CG 3.95Å; H336-W373 AromaticContact CD2-NE1 3.8Å; H336-W373 AromaticContact NE2-CD1 3.59Å; H336-W373 AromaticContact NE2-CG 3.75Å; V343-W373 HydrophobicContact CG2-CE3 4.1Å; V343-W373 HydrophobicContact CG2-CH2 4.35Å; V343-W373 HydrophobicContact CG2-CZ3 3.46Å; V343-W373 VanDerWaalsContact CG2-CZ3 3.46Å; Q369-W373 WeakPolarHBondContact O-CB 3.49Å; Q369-W373 PolarHBondContact O-N 3.48Å; W373-V375 PolarHBondContact O-N 3.46Å; W373-V376 PolarHBondContact O-N 3.5Å; W373-T377 WeakPolarHBondContact O-CG2 3.37Å; W373-T377 PolarHBondContact O-N 2.98Å; W373-T377 PolarHBondContact O-OG1 3.38Å
374	F	91.9	Very high	88.4	Confident	5 Å²	5	57.1 Å²	57.1	2%	0.022	28%	0.283	C	S	.	.	H	α-helix	trans	-59.9	-46.2	-180	175.3	-87.6	0	0	0	113.1	F142 A180 V181 I184 L185 Y332 T370 L371 V372 T377 L378	F142-F374 HydrophobicContact CE1-CE2 4.31Å; F142-F374 HydrophobicContact CZ-CD2 4Å; F142-F374 AromaticContact CZ-CE2 3.65Å; F142-F374 HydrophobicContact CZ-CE2 3.65Å; F142-F374 HydrophobicContact CZ-CZ 4.24Å; A180-F374 HydrophobicContact CB-CE2 4.16Å; A180-F374 HydrophobicContact CB-CZ 3.65Å; A180-F374 WeakPolarHBondContact O-CZ 3.44Å; V181-F374 HydrophobicContact CG2-CE1 4.45Å; I184-F374 HydrophobicContact CB-CE2 4.36Å; I184-F374 HydrophobicContact CG2-CE2 4.08Å; L185-F374 HydrophobicContact CB-CD2 4.45Å; L185-F374 HydrophobicContact CB-CE1 4.38Å; L185-F374 HydrophobicContact CB-CE2 3.91Å; L185-F374 HydrophobicContact CB-CZ 3.87Å; L185-F374 HydrophobicContact CD1-CD1 4.3Å; L185-F374 HydrophobicContact CD1-CD2 4.28Å; L185-F374 HydrophobicContact CD1-CG 4.16Å; L185-F374 HydrophobicContact CD2-CE1 4.47Å; Y332-F374 HydrophobicContact CE1-CD2 4.37Å; T370-F374 WeakPolarHBondContact O-CB 3.45Å; T370-F374 PolarHBondContact O-N 2.99Å; L371-F374 PolarHBondContact O-N 3.49Å; V372-F374 PolarHBondContact O-N 3.45Å; F374-T377 PolarHBondContact O-OG1 3.37Å; F374-T377 VanDerWaalsContact O-OG1 3.09Å; F374-L378 HydrophobicContact CE1-CD2 4.04Å; F374-L378 HydrophobicContact CZ-CD2 4.42Å; F374-L378 WeakPolarHBondContact O-CB 3.21Å; F374-L378 PolarHBondContact O-N 3.27Å
375	V	93.7	Very high	88.2	Confident	77 Å²	77	51.7 Å²	51.7	47%	0.467	28%	0.275	S	S	.	.	H	α-helix	trans	-65.8	-43.8	-179.1	169.5	0	0	0	0	110.4	L371 V372 W373 L378 V379	L371-V375 WeakPolarHBondContact O-CB 3.34Å; L371-V375 VanDerWaalsContact O-CG2 3.23Å; L371-V375 WeakPolarHBondContact O-CG2 3.48Å; L371-V375 PolarHBondContact O-N 3.06Å; V372-V375 PolarHBondContact O-N 2.96Å; W373-V375 PolarHBondContact O-N 3.46Å; V375-L378 PolarHBondContact O-N 2.9Å; V375-V379 HydrophobicContact CG1-CG2 4.35Å; V375-V379 WeakPolarHBondContact O-CB 3.39Å; V375-V379 VanDerWaalsContact O-CG2 3.25Å; V375-V379 WeakPolarHBondContact O-CG2 3.29Å; V375-V379 PolarHBondContact O-N 3.15Å
376	V	94.7	Very high	88.2	Confident	62 Å²	62	53.2 Å²	53.2	38%	0.376	29%	0.285	S	S	.	.	H	α-helix	trans	-67.2	-44.6	-179	-179.9	0	0	0	0	110.8	F135 V372 W373 L378 V379 L380	F135-V376 HydrophobicContact CE2-CB 4.39Å; F135-V376 HydrophobicContact CE2-CG1 4.1Å; F135-V376 HydrophobicContact CZ-CB 4.46Å; F135-V376 HydrophobicContact CZ-CG1 3.73Å; V372-V376 HydrophobicContact CG1-CG2 4.32Å; V372-V376 WeakPolarHBondContact O-CB 3.41Å; V372-V376 WeakPolarHBondContact O-CG2 3.34Å; V372-V376 PolarHBondContact O-N 3.01Å; W373-V376 PolarHBondContact O-N 3.5Å; V376-L378 VanDerWaalsContact C-N 3.34Å; V376-L378 PolarHBondContact O-N 2.81Å; V376-V379 PolarHBondContact O-N 3.48Å; V376-L380 HydrophobicContact CG1-CD1 4.07Å; V376-L380 HydrophobicContact CG1-CG 4.48Å; V376-L380 WeakPolarHBondContact O-CG 3.36Å; V376-L380 PolarHBondContact O-N 2.92Å
377	T	94.1	Very high	88.6	Confident	0 Å²	0	52.8 Å²	52.8	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-64.5	-38.8	177.5	53.5	0	0	0	0	112.1	F135 C138 I139 Y332 W373 F374 A381	F135-T377 HydrophobicContact CD2-CG2 3.46Å; F135-T377 VanDerWaalsContact CD2-CG2 3.46Å; F135-T377 HydrophobicContact CE1-CG2 4.45Å; F135-T377 HydrophobicContact CE2-CG2 3.37Å; F135-T377 HydrophobicContact CG-CG2 4.07Å; F135-T377 HydrophobicContact CZ-CG2 3.91Å; C138-T377 HydrophobicContact CB-CG2 3.92Å; I139-T377 HydrophobicContact CG1-CG2 4.04Å; Y332-T377 PolarHBondContact OH-OG1 3.41Å; W373-T377 WeakPolarHBondContact O-CG2 3.37Å; W373-T377 PolarHBondContact O-N 2.98Å; W373-T377 PolarHBondContact O-OG1 3.38Å; F374-T377 PolarHBondContact O-OG1 3.37Å; F374-T377 VanDerWaalsContact O-OG1 3.09Å; T377-A381 WeakPolarHBondContact O-CB 3.36Å; T377-A381 PolarHBondContact O-N 3.25Å
378	L	93.6	Very high	88.8	Confident	17 Å²	17	49.7 Å²	49.7	9%	0.089	27%	0.271	C	S	.	.	H	α-helix	trans	-62.2	-50.4	175.2	176.7	60.9	0	0	0	111.3	F142 I176 V177 A180 F374 V375 V376 L380 A381 L382	F142-L378 HydrophobicContact CD1-CD1 4.35Å; F142-L378 HydrophobicContact CD2-CB 4.41Å; F142-L378 HydrophobicContact CE1-CD1 4.36Å; F142-L378 HydrophobicContact CE2-CB 3.97Å; F142-L378 HydrophobicContact CG-CD1 4.45Å; F142-L378 HydrophobicContact CZ-CB 4.33Å; F142-L378 HydrophobicContact CZ-CD1 4.44Å; I176-L378 HydrophobicContact CG2-CD1 3.65Å; V177-L378 HydrophobicContact CG2-CD1 4.43Å; V177-L378 HydrophobicContact CG2-CD2 4.42Å; A180-L378 HydrophobicContact CB-CD1 4.01Å; A180-L378 HydrophobicContact CB-CD2 4.31Å; F374-L378 HydrophobicContact CE1-CD2 4.04Å; F374-L378 HydrophobicContact CZ-CD2 4.42Å; F374-L378 WeakPolarHBondContact O-CB 3.21Å; F374-L378 PolarHBondContact O-N 3.27Å; V375-L378 PolarHBondContact O-N 2.9Å; V376-L378 VanDerWaalsContact C-N 3.34Å; V376-L378 PolarHBondContact O-N 2.81Å; L378-L380 VanDerWaalsContact C-N 3.34Å; L378-L380 PolarHBondContact O-N 3.47Å; L378-A381 PolarHBondContact O-N 2.85Å; L378-L382 WeakPolarHBondContact O-CG 3.11Å; L378-L382 PolarHBondContact O-N 3Å; L378-L382 VanDerWaalsContact O-N 3.1Å
379	V	93.9	Very high	88.7	Confident	67 Å²	67	50.3 Å²	50.3	41%	0.406	27%	0.265	S	S	.	.	H	α-helix	trans	-59	-46.6	179.6	170.1	0	0	0	0	110.6	V375 V376 A381 L382 F383	V375-V379 HydrophobicContact CG1-CG2 4.35Å; V375-V379 WeakPolarHBondContact O-CB 3.39Å; V375-V379 VanDerWaalsContact O-CG2 3.25Å; V375-V379 WeakPolarHBondContact O-CG2 3.29Å; V375-V379 PolarHBondContact O-N 3.15Å; V376-V379 PolarHBondContact O-N 3.48Å; V379-A381 VanDerWaalsContact C-N 3.35Å; V379-A381 PolarHBondContact O-N 3.18Å; V379-L382 WeakPolarHBondContact O-CB 3.31Å; V379-L382 PolarHBondContact O-N 3.06Å; V379-F383 HydrophobicContact CG1-CD2 4.11Å; V379-F383 HydrophobicContact CG1-CE2 3.84Å; V379-F383 WeakPolarHBondContact O-CD2 3.35Å
380	L	92.6	Very high	88.8	Confident	65 Å²	65	49.5 Å²	49.5	34%	0.34	26%	0.262	S	S	.	.	H	α-helix	trans	-61	-42.5	177.4	-70.3	173.9	0	0	0	112.1	F135 I139 V376 L378 L382 F383 I384	F135-L380 HydrophobicContact CE1-CD1 3.67Å; F135-L380 HydrophobicContact CZ-CD1 3.64Å; I139-L380 HydrophobicContact CD1-CB 3.95Å; I139-L380 HydrophobicContact CD1-CD1 3.72Å; I139-L380 HydrophobicContact CG1-CB 4.33Å; V376-L380 HydrophobicContact CG1-CD1 4.07Å; V376-L380 HydrophobicContact CG1-CG 4.48Å; V376-L380 WeakPolarHBondContact O-CG 3.36Å; V376-L380 PolarHBondContact O-N 2.92Å; L378-L380 VanDerWaalsContact C-N 3.34Å; L378-L380 PolarHBondContact O-N 3.47Å; L380-L382 PolarHBondContact O-N 3.38Å; L380-F383 PolarHBondContact O-N 3.36Å; L380-F383 VanDerWaalsContact O-N 3.07Å; L380-I384 HydrophobicContact CB-CD1 4.23Å; L380-I384 VanDerWaalsContact O-CG1 3.32Å; L380-I384 WeakPolarHBondContact O-CG1 3.12Å; L380-I384 PolarHBondContact O-N 3.45Å
381	A	91.6	Very high	88.9	Confident	0 Å²	0	49.3 Å²	49.3	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-63.7	-25.9	177.6	0	0	0	0	0	113.7	I139 F142 I143 T377 L378 V379 F383	I139-A381 HydrophobicContact CG2-CB 4.12Å; F142-A381 HydrophobicContact CB-CB 3.41Å; F142-A381 VanDerWaalsContact CB-CB 3.41Å; F142-A381 HydrophobicContact CD2-CB 4.23Å; F142-A381 HydrophobicContact CG-CB 4.23Å; I143-A381 HydrophobicContact CG1-CB 4.22Å; T377-A381 WeakPolarHBondContact O-CB 3.36Å; T377-A381 PolarHBondContact O-N 3.25Å; L378-A381 PolarHBondContact O-N 2.85Å; V379-A381 VanDerWaalsContact C-N 3.35Å; V379-A381 PolarHBondContact O-N 3.18Å; A381-F383 VanDerWaalsContact C-N 3.31Å
382	L	89.5	Confident	88.7	Confident	37 Å²	37	47 Å²	47	19%	0.194	25%	0.252	C	S	.	.	H	α-helix	trans	-73.9	-21.6	174.9	-65.6	175.1	0	0	0	113.3	K173 I176 V177 L378 V379 L380	K173-L382 HydrophobicContact CB-CD2 4.03Å; K173-L382 HydrophobicContact CG-CD2 4.14Å; I176-L382 HydrophobicContact CB-CD2 4.23Å; I176-L382 HydrophobicContact CD1-CD2 4.16Å; I176-L382 HydrophobicContact CG2-CD2 4.2Å; V177-L382 HydrophobicContact CG2-CD1 4.02Å; V177-L382 HydrophobicContact CG2-CD2 4.35Å; L378-L382 WeakPolarHBondContact O-CG 3.11Å; L378-L382 PolarHBondContact O-N 3Å; L378-L382 VanDerWaalsContact O-N 3.1Å; V379-L382 WeakPolarHBondContact O-CB 3.31Å; V379-L382 PolarHBondContact O-N 3.06Å; L380-L382 PolarHBondContact O-N 3.38Å
383	F	88.6	Confident	88.4	Confident	158 Å²	158	47.2 Å²	47.2	69%	0.693	25%	0.25	S	C	*	.	H	α-helix	trans	-102.8	-21.3	-179.8	-69.8	-70	0	0	0	113.7	V379 L380 A381 P385	V379-F383 HydrophobicContact CG1-CD2 4.11Å; V379-F383 HydrophobicContact CG1-CE2 3.84Å; V379-F383 WeakPolarHBondContact O-CD2 3.35Å; L380-F383 PolarHBondContact O-N 3.36Å; L380-F383 VanDerWaalsContact O-N 3.07Å; A381-F383 VanDerWaalsContact C-N 3.31Å; F383-P385 VanDerWaalsContact O-CD 3.28Å; F383-P385 WeakPolarHBondContact O-CD 3.2Å
384	I	86	Confident	88.4	Confident	47 Å²	47	46 Å²	46	24%	0.241	25%	0.245	C	C	.	.			trans	-89.6	111.9	178.3	-63	165.1	0	0	0	108.8	I139 I143 L380 V390	I139-I384 HydrophobicContact CG2-CD1 3.91Å; I143-I384 HydrophobicContact CD1-CB 4.1Å; I143-I384 HydrophobicContact CD1-CG2 3.75Å; L380-I384 HydrophobicContact CB-CD1 4.23Å; L380-I384 VanDerWaalsContact O-CG1 3.32Å; L380-I384 WeakPolarHBondContact O-CG1 3.12Å; L380-I384 PolarHBondContact O-N 3.45Å; I384-V390 HydrophobicContact CG2-CG2 3.9Å
385	P	73.8	Confident	88.3	Confident	97 Å²	97	45.7 Å²	45.7	63%	0.63	24%	0.244	S	C	*	.			trans	-84.9	-16.9	-177.2	33.7	-35.3	0	0	0	113.3	F383	F383-P385 VanDerWaalsContact O-CD 3.28Å; F383-P385 WeakPolarHBondContact O-CD 3.2Å
386	D	80.3	Confident	88.2	Confident	59 Å²	59	42 Å²	42	32%	0.316	22%	0.222	S	C	.	.			trans	-123	117.6	-169.4	-169.9	-16.6	0	0	0	111.5	G388 R389	D386-G388 VanDerWaalsContact C-N 3.28Å; D386-G388 PolarHBondContact O-N 3.36Å; D386-G388 WeakPolarHBondContact OD1-CA 3.28Å; D386-G388 PolarHBondContact OD1-N 3.48Å; D386-R389 IonicContact OD2-NH1 2.72Å
387	I	85.5	Confident	88.1	Confident	7 Å²	7	40 Å²	40	4%	0.036	21%	0.208	C	C	.	.	H	α-helix	trans	-66.6	-29.3	175.6	-161.9	-176.8	0	0	0	112.5	A140 I143 V144 Q304 R389 V390 I391	A140-I387 HydrophobicContact CB-CG1 4.22Å; I143-I387 HydrophobicContact CG2-CB 3.92Å; I143-I387 HydrophobicContact CG2-CG1 4.41Å; V144-I387 HydrophobicContact CG2-CD1 3.26Å; Q304-I387 HydrophobicContact CB-CG2 3.95Å; I387-R389 PolarHBondContact O-N 3.22Å; I387-V390 WeakPolarHBondContact O-CB 3.33Å; I387-V390 PolarHBondContact O-N 3.24Å; I387-V390 VanDerWaalsContact O-N 3.13Å; I387-I391 HydrophobicContact CD1-CD1 3.83Å; I387-I391 HydrophobicContact CG1-CD1 3.71Å; I387-I391 HydrophobicContact CG1-CG1 4.15Å; I387-I391 HydrophobicContact CG2-CD1 4.41Å; I387-I391 WeakPolarHBondContact O-CG1 3.35Å; I387-I391 PolarHBondContact O-N 2.79Å
388	G	85	Confident	88.1	Confident	12 Å²	12	40 Å²	40	12%	0.124	21%	0.208	C	C	.	.	H	α-helix	trans	-60.5	-42	-177.3	0	0	0	0	0	112.8	D386 V390 I391 S392	D386-G388 VanDerWaalsContact C-N 3.28Å; D386-G388 PolarHBondContact O-N 3.36Å; D386-G388 WeakPolarHBondContact OD1-CA 3.28Å; D386-G388 PolarHBondContact OD1-N 3.48Å; G388-V390 VanDerWaalsContact C-N 3.31Å; G388-V390 PolarHBondContact O-N 3.29Å; G388-I391 PolarHBondContact O-N 2.94Å; G388-S392 PolarHBondContact O-N 3.46Å
389	R	84.4	Confident	88.1	Confident	124 Å²	124	39.1 Å²	39.1	47%	0.468	20%	0.204	S	C	.	.	H	α-helix	trans	-61.5	-39.7	175	-67.8	-169.4	-179.5	90.1	-3.7	112.4	D386 I387 S392 D454	D386-R389 IonicContact OD2-NH1 2.72Å; I387-R389 PolarHBondContact O-N 3.22Å; R389-S392 PolarHBondContact O-OG 3.3Å; R389-D454 IonicContact NE-OD1 2.81Å
390	V	87.9	Confident	88.1	Confident	14 Å²	14	36.6 Å²	36.6	9%	0.085	19%	0.189	C	C	.	.	H	α-helix	trans	-67.5	-44.4	177.5	-175.5	0	0	0	0	109.6	G136 I139 A140 I143 I384 I387 G388 L393 I394	G136-V390 WeakPolarHBondContact O-CG1 3.38Å; I139-V390 HydrophobicContact CG2-CG2 4.31Å; A140-V390 HydrophobicContact CB-CG1 4.07Å; I143-V390 HydrophobicContact CD1-CG2 4.06Å; I384-V390 HydrophobicContact CG2-CG2 3.9Å; I387-V390 WeakPolarHBondContact O-CB 3.33Å; I387-V390 PolarHBondContact O-N 3.24Å; I387-V390 VanDerWaalsContact O-N 3.13Å; G388-V390 VanDerWaalsContact C-N 3.31Å; G388-V390 PolarHBondContact O-N 3.29Å; V390-L393 PolarHBondContact O-N 3.43Å; V390-I394 HydrophobicContact CG1-CD1 4.16Å; V390-I394 HydrophobicContact CG1-CG2 4.48Å; V390-I394 VanDerWaalsContact O-CG1 3.3Å; V390-I394 WeakPolarHBondContact O-CG1 3.48Å; V390-I394 PolarHBondContact O-N 2.88Å
391	I	87.1	Confident	88.3	Confident	1 Å²	1	33.5 Å²	33.5	1%	0.005	17%	0.173	C	C	.	.	H	α-helix	trans	-65.4	-38.9	-179	-71.1	172.3	0	0	0	112.4	N66 T246 F249 I387 G388 L393 G395	N66-I391 WeakPolarHBondContact ND2-CD1 3.23Å; T246-I391 HydrophobicContact CG2-CG2 4.28Å; F249-I391 HydrophobicContact CB-CG2 4.3Å; F249-I391 HydrophobicContact CD1-CD1 4.13Å; F249-I391 HydrophobicContact CD1-CG1 3.96Å; F249-I391 HydrophobicContact CD1-CG2 4.06Å; F249-I391 HydrophobicContact CE1-CD1 3.94Å; F249-I391 HydrophobicContact CE1-CG1 3.89Å; F249-I391 HydrophobicContact CG-CG2 4.31Å; F249-I391 HydrophobicContact CZ-CG1 4.44Å; I387-I391 HydrophobicContact CD1-CD1 3.83Å; I387-I391 HydrophobicContact CG1-CD1 3.71Å; I387-I391 HydrophobicContact CG1-CG1 4.15Å; I387-I391 HydrophobicContact CG2-CD1 4.41Å; I387-I391 WeakPolarHBondContact O-CG1 3.35Å; I387-I391 PolarHBondContact O-N 2.79Å; G388-I391 PolarHBondContact O-N 2.94Å; I391-L393 VanDerWaalsContact C-N 3.31Å; I391-L393 PolarHBondContact O-N 2.95Å; I391-G395 VanDerWaalsContact O-CA 3.29Å; I391-G395 WeakPolarHBondContact O-CA 3.5Å; I391-G395 PolarHBondContact O-N 3.44Å
392	S	84.6	Confident	88.4	Confident	28 Å²	28	33.5 Å²	33.5	20%	0.196	17%	0.173	C	C	.	.	H	α-helix	trans	-62.4	-41.2	178.4	69.6	0	0	0	0	111.4	G388 R389 G396 S450	G388-S392 PolarHBondContact O-N 3.46Å; R389-S392 PolarHBondContact O-OG 3.3Å; S392-G396 PolarHBondContact O-N 3.24Å; S392-S450 WeakPolarHBondContact CB-OG 2.81Å; S392-S450 PolarHBondContact OG-OG 3.23Å
393	L	86.2	Confident	88.7	Confident	85 Å²	85	31.8 Å²	31.8	45%	0.445	16%	0.164	S	C	.	.	H	α-helix	trans	-69.2	-54.7	177.2	-178.1	66.6	0	0	0	112.3	V390 I391 G395 G396 L397	V390-L393 PolarHBondContact O-N 3.43Å; I391-L393 VanDerWaalsContact C-N 3.31Å; I391-L393 PolarHBondContact O-N 2.95Å; L393-G395 VanDerWaalsContact C-N 3.32Å; L393-G395 PolarHBondContact O-N 3.21Å; L393-G396 PolarHBondContact O-N 3.18Å; L393-L397 PolarHBondContact O-N 3.01Å
394	I	91.5	Very high	89.1	Confident	3 Å²	3	25.3 Å²	25.3	2%	0.015	14%	0.138	C	C	.	.	H	α-helix	trans	-72.9	-25.4	-177.2	69	-172.9	0	0	0	112.5	Y133 F249 V390 G396 L397 A398	Y133-I394 HydrophobicContact CD2-CB 3.93Å; Y133-I394 WeakPolarHBondContact CD2-O 3.3Å; Y133-I394 HydrophobicContact CE2-CB 4.13Å; Y133-I394 HydrophobicContact CE2-CG1 4.47Å; F249-I394 HydrophobicContact CD2-CD1 3.57Å; F249-I394 HydrophobicContact CD2-CG1 3.74Å; F249-I394 HydrophobicContact CE2-CD1 3.28Å; F249-I394 HydrophobicContact CE2-CG1 4.01Å; F249-I394 HydrophobicContact CG-CD1 4.48Å; F249-I394 HydrophobicContact CG-CG1 4.47Å; F249-I394 HydrophobicContact CZ-CD1 4Å; V390-I394 HydrophobicContact CG1-CD1 4.16Å; V390-I394 HydrophobicContact CG1-CG2 4.48Å; V390-I394 VanDerWaalsContact O-CG1 3.3Å; V390-I394 WeakPolarHBondContact O-CG1 3.48Å; V390-I394 PolarHBondContact O-N 2.88Å; I394-G396 VanDerWaalsContact C-N 3.35Å; I394-L397 CarbonylContact O-C 3.42Å; I394-L397 WeakPolarHBondContact O-CB 3.38Å; I394-L397 PolarHBondContact O-N 3.28Å; I394-A398 WeakPolarHBondContact O-CB 3.21Å; I394-A398 PolarHBondContact O-N 3.35Å
395	G	89.8	Confident	89.7	Confident	0 Å²	0	23.9 Å²	23.9	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-67.6	-34.6	174.5	0	0	0	0	0	112.4	P245 I391 L393 A398 A399	P245-G395 WeakPolarHBondContact O-CA 3.48Å; I391-G395 VanDerWaalsContact O-CA 3.29Å; I391-G395 WeakPolarHBondContact O-CA 3.5Å; I391-G395 PolarHBondContact O-N 3.44Å; L393-G395 VanDerWaalsContact C-N 3.32Å; L393-G395 PolarHBondContact O-N 3.21Å; G395-A398 WeakPolarHBondContact O-CB 3.24Å; G395-A398 PolarHBondContact O-N 3.22Å; G395-A399 PolarHBondContact O-N 3.44Å; G395-A399 VanDerWaalsContact O-N 3.08Å
396	G	90.7	Very high	90.7	Very high	0 Å²	0	19.2 Å²	19.2	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-60.4	-48	167.7	0	0	0	0	0	111.6	S392 L393 I394 A398 A399 C400 F443 T446	S392-G396 PolarHBondContact O-N 3.24Å; L393-G396 PolarHBondContact O-N 3.18Å; I394-G396 VanDerWaalsContact C-N 3.35Å; G396-A398 VanDerWaalsContact C-N 3.28Å; G396-A398 PolarHBondContact O-N 2.96Å; G396-A399 WeakPolarHBondContact O-CB 3.3Å; G396-A399 PolarHBondContact O-N 2.93Å; G396-A399 VanDerWaalsContact O-N 3.16Å; G396-C400 PolarHBondContact O-N 3.32Å; G396-F443 WeakPolarHBondContact O-CD2 3.25Å; G396-T446 WeakPolarHBondContact CA-OG1 3.04Å
397	L	93.3	Very high	91.5	Very high	18 Å²	18	16.4 Å²	16.4	9%	0.094	8%	0.084	C	C	.	.	H	α-helix	trans	-62.8	-34.8	174.4	-69.8	172.6	0	0	0	112.3	A129 I132 Y133 L393 I394 A399 C400 F401 F443	A129-L397 HydrophobicContact CB-CD2 4.45Å; I132-L397 HydrophobicContact CB-CD1 3.99Å; I132-L397 HydrophobicContact CG2-CD1 3.53Å; Y133-L397 HydrophobicContact CD2-CB 4.26Å; L393-L397 PolarHBondContact O-N 3.01Å; I394-L397 CarbonylContact O-C 3.42Å; I394-L397 WeakPolarHBondContact O-CB 3.38Å; I394-L397 PolarHBondContact O-N 3.28Å; L397-A399 VanDerWaalsContact C-N 3.27Å; L397-A399 PolarHBondContact O-N 2.93Å; L397-C400 VanDerWaalsContact O-CB 3.29Å; L397-C400 WeakPolarHBondContact O-CB 3.42Å; L397-C400 PolarHBondContact O-N 3.49Å; L397-F401 HydrophobicContact CB-CE2 4.34Å; L397-F401 VanDerWaalsContact O-CD2 3.28Å; L397-F401 WeakPolarHBondContact O-CD2 3.49Å; L397-F401 WeakPolarHBondContact O-CE2 3.35Å; L397-F401 PolarHBondContact O-N 2.76Å; L397-F443 HydrophobicContact CD2-CE2 3.74Å; L397-F443 HydrophobicContact CD2-CZ 4.44Å; L397-F443 HydrophobicContact CG-CE2 4.35Å
398	A	93.8	Very high	92.1	Very high	0 Å²	0	18.1 Å²	18.1	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-60.6	-38.7	175.2	0	0	0	0	0	111.6	Y133 C248 Q252 I394 G395 G396 C400 F401 I402	Y133-A398 HydrophobicContact CE2-CB 3.98Å; C248-A398 HydrophobicContact CB-CB 3.96Å; Q252-A398 HydrophobicContact CB-CB 4.15Å; Q252-A398 HydrophobicContact CG-CB 4.22Å; Q252-A398 PolarHBondContact NE2-O 3.23Å; I394-A398 WeakPolarHBondContact O-CB 3.21Å; I394-A398 PolarHBondContact O-N 3.35Å; G395-A398 WeakPolarHBondContact O-CB 3.24Å; G395-A398 PolarHBondContact O-N 3.22Å; G396-A398 VanDerWaalsContact C-N 3.28Å; G396-A398 PolarHBondContact O-N 2.96Å; A398-C400 PolarHBondContact O-N 2.8Å; A398-F401 PolarHBondContact O-N 3.39Å; A398-F401 VanDerWaalsContact O-N 3.1Å; A398-I402 VanDerWaalsContact O-CG1 3.31Å; A398-I402 WeakPolarHBondContact O-CG1 3.45Å; A398-I402 PolarHBondContact O-N 3.18Å
399	A	93.6	Very high	92.6	Very high	0 Å²	0	17.6 Å²	17.6	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-59.8	-35.8	173.5	0	0	0	0	0	111.8	G395 G396 L397 F401 I402 F403 I442	G395-A399 PolarHBondContact O-N 3.44Å; G395-A399 VanDerWaalsContact O-N 3.08Å; G396-A399 WeakPolarHBondContact O-CB 3.3Å; G396-A399 PolarHBondContact O-N 2.93Å; G396-A399 VanDerWaalsContact O-N 3.16Å; L397-A399 VanDerWaalsContact C-N 3.27Å; L397-A399 PolarHBondContact O-N 2.93Å; A399-F401 VanDerWaalsContact C-N 3.34Å; A399-F401 PolarHBondContact O-N 3.13Å; A399-I402 PolarHBondContact O-N 3.11Å; A399-F403 HydrophobicContact CB-CD2 4.1Å; A399-F403 VanDerWaalsContact O-CB 3.29Å; A399-F403 WeakPolarHBondContact O-CB 3.37Å; A399-F403 VanDerWaalsContact O-CD2 3.27Å; A399-F403 WeakPolarHBondContact O-CD2 3.32Å; A399-F403 PolarHBondContact O-N 3.34Å; A399-I442 HydrophobicContact CB-CB 4.06Å; A399-I442 HydrophobicContact CB-CG2 3.57Å
400	C	95.1	Very high	93.1	Very high	14 Å²	14	12.2 Å²	12.2	10%	0.095	7%	0.068	C	C	.	.	I	π-helix	trans	-61.1	-41	174	-65.7	0	0	0	0	112.6	G396 L397 A398 V404 F405 F443	G396-C400 PolarHBondContact O-N 3.32Å; L397-C400 VanDerWaalsContact O-CB 3.29Å; L397-C400 WeakPolarHBondContact O-CB 3.42Å; L397-C400 PolarHBondContact O-N 3.49Å; A398-C400 PolarHBondContact O-N 2.8Å; C400-V404 HydrophobicContact CB-CB 4.4Å; C400-V404 HydrophobicContact CB-CG2 4.45Å; C400-V404 WeakPolarHBondContact O-CB 3.35Å; C400-V404 PolarHBondContact O-N 2.91Å; C400-F405 HydrophobicContact CB-CD2 4.35Å; C400-F405 HydrophobicContact CB-CE2 4.01Å; C400-F405 WeakPolarHBondContact O-CD2 3.33Å; C400-F405 PolarHBondContact O-N 3.42Å; C400-F443 VanDerWaalsContact SG-CG 3.53Å
401	F	95	Very high	93.4	Very high	0 Å²	0	13.4 Å²	13.4	0%	0	7%	0.073	C	C	.	.	I	π-helix	trans	-76.6	-27.2	179.9	-47.8	-58.9	0	0	0	114.3	Y110 A129 I130 Y133 H254 V255 L397 A398 A399 F405 P406	Y110-F401 HydrophobicContact CE1-CD1 4.16Å; Y110-F401 VanDerWaalsContact OH-CA 3.25Å; Y110-F401 WeakPolarHBondContact OH-CA 3.25Å; Y110-F401 PolarHBondContact OH-O 3.41Å; A129-F401 VanDerWaalsContact C-CZ 3.49Å; A129-F401 HydrophobicContact CB-CE1 3.73Å; A129-F401 HydrophobicContact CB-CZ 3.74Å; I130-F401 HydrophobicContact CG1-CD1 4.27Å; I130-F401 HydrophobicContact CG1-CE1 3.57Å; I130-F401 HydrophobicContact CG1-CZ 3.94Å; Y133-F401 HydrophobicContact CD1-CE2 4.01Å; Y133-F401 AromaticContact CD2-CE2 3.91Å; Y133-F401 HydrophobicContact CD2-CE2 3.91Å; Y133-F401 HydrophobicContact CG-CD2 4.36Å; Y133-F401 AromaticContact CG-CE2 3.53Å; Y133-F401 HydrophobicContact CG-CE2 3.53Å; Y133-F401 HydrophobicContact CG-CZ 4.35Å; H254-F401 HydrophobicContact CB-CB 4.37Å; V255-F401 HydrophobicContact CG2-CB 4.44Å; V255-F401 HydrophobicContact CG2-CD1 4.36Å; V255-F401 HydrophobicContact CG2-CD2 3.8Å; V255-F401 HydrophobicContact CG2-CE2 4.16Å; V255-F401 HydrophobicContact CG2-CG 3.95Å; L397-F401 HydrophobicContact CB-CE2 4.34Å; L397-F401 VanDerWaalsContact O-CD2 3.28Å; L397-F401 WeakPolarHBondContact O-CD2 3.49Å; L397-F401 WeakPolarHBondContact O-CE2 3.35Å; L397-F401 PolarHBondContact O-N 2.76Å; A398-F401 PolarHBondContact O-N 3.39Å; A398-F401 VanDerWaalsContact O-N 3.1Å; A399-F401 VanDerWaalsContact C-N 3.34Å; A399-F401 PolarHBondContact O-N 3.13Å; F401-F405 AromaticContact CD1-CD2 3.66Å; F401-F405 HydrophobicContact CD1-CD2 3.66Å; F401-F405 AromaticContact CD1-CE2 3.72Å; F401-F405 HydrophobicContact CD1-CE2 3.72Å; F401-F405 HydrophobicContact CE1-CD2 4.18Å; F401-F405 AromaticContact CE1-CE2 3.75Å; F401-F405 HydrophobicContact CE1-CE2 3.75Å; F401-P406 VanDerWaalsContact O-CD 3.23Å; F401-P406 WeakPolarHBondContact O-CD 3.39Å; F401-P406 WeakPolarHBondContact O-CG 3.47Å
402	I	95.7	Very high	93.6	Very high	0 Å²	0	17.6 Å²	17.6	0%	0	9%	0.093	C	C	.	.	I	π-helix	trans	-79.9	-42.5	178.3	-65.1	166	0	0	0	110.6	I91 C248 A398 A399 M435	I91-I402 HydrophobicContact CG1-CD1 4.43Å; I91-I402 HydrophobicContact CG1-CG2 3.7Å; C248-I402 HydrophobicContact CB-CD1 3.8Å; C248-I402 WeakPolarHBondContact O-CD1 3.43Å; A398-I402 VanDerWaalsContact O-CG1 3.31Å; A398-I402 WeakPolarHBondContact O-CG1 3.45Å; A398-I402 PolarHBondContact O-N 3.18Å; A399-I402 PolarHBondContact O-N 3.11Å; I402-M435 VanDerWaalsContact O-CE 3.31Å; I402-M435 WeakPolarHBondContact O-CE 3.26Å
403	F	95.9	Very high	93.8	Very high	0 Å²	0	17 Å²	17	0%	0	9%	0.09	C	C	.	.	I	π-helix	trans	-111.3	-59.4	-167.7	-62.5	-86.4	0	0	0	112.7	M87 F90 A399 G407 M435 L438 G439 I442	M87-F403 HydrophobicContact CE-CE1 4.47Å; M87-F403 HydrophobicContact CE-CZ 4.01Å; M87-F403 HydrophobicContact SD-CE1 4.44Å; M87-F403 HydrophobicContact SD-CE2 4.1Å; M87-F403 HydrophobicContact SD-CZ 3.48Å; M87-F403 WeakPolarHBondContact SD-CZ 3.23Å; F90-F403 HydrophobicContact CB-CD1 3.8Å; F90-F403 HydrophobicContact CB-CE1 3.24Å; F90-F403 HydrophobicContact CB-CZ 3.99Å; F90-F403 HydrophobicContact CD1-CD1 4.34Å; F90-F403 HydrophobicContact CD1-CE1 4.2Å; F90-F403 AromaticContact CD2-CE1 3.73Å; F90-F403 HydrophobicContact CD2-CE1 3.73Å; F90-F403 HydrophobicContact CG-CD1 4.02Å; F90-F403 AromaticContact CG-CE1 3.47Å; F90-F403 HydrophobicContact CG-CE1 3.47Å; F90-F403 VanDerWaalsContact CG-CE1 3.47Å; F90-F403 HydrophobicContact CG-CZ 4.48Å; A399-F403 HydrophobicContact CB-CD2 4.1Å; A399-F403 VanDerWaalsContact O-CB 3.29Å; A399-F403 WeakPolarHBondContact O-CB 3.37Å; A399-F403 VanDerWaalsContact O-CD2 3.27Å; A399-F403 WeakPolarHBondContact O-CD2 3.32Å; A399-F403 PolarHBondContact O-N 3.34Å; F403-G407 WeakPolarHBondContact O-CA 3.33Å; F403-G407 PolarHBondContact O-N 2.84Å; F403-M435 WeakPolarHBondContact CB-O 3.24Å; F403-L438 HydrophobicContact CD1-CD2 4.1Å; F403-L438 HydrophobicContact CD1-CG 4.47Å; F403-L438 HydrophobicContact CE1-CD2 3.77Å; F403-L438 HydrophobicContact CE1-CG 4.45Å; F403-G439 VanDerWaalsContact CB-CA 3.47Å; F403-I442 HydrophobicContact CE2-CD1 4.22Å; F403-I442 HydrophobicContact CZ-CD1 4.45Å
404	V	96.9	Very high	93.9	Very high	23 Å²	23	14.5 Å²	14.5	14%	0.139	8%	0.075	C	C	.	.	I	π-helix	trans	-66.9	-58.7	-167.6	-179.7	0	0	0	0	111.8	C400 G407 L408	C400-V404 HydrophobicContact CB-CB 4.4Å; C400-V404 HydrophobicContact CB-CG2 4.45Å; C400-V404 WeakPolarHBondContact O-CB 3.35Å; C400-V404 PolarHBondContact O-N 2.91Å; V404-G407 PolarHBondContact O-N 3.02Å; V404-L408 HydrophobicContact CG1-CD1 4.04Å; V404-L408 HydrophobicContact CG1-CG 4.47Å; V404-L408 WeakPolarHBondContact O-CG 3.33Å; V404-L408 PolarHBondContact O-N 2.8Å
405	F	96.7	Very high	93.7	Very high	16 Å²	16	18.8 Å²	18.8	7%	0.07	10%	0.098	C	C	.	.	H	α-helix	trans	-66.2	-44.4	-175.4	-64.4	-63.2	0	0	0	112.9	Y110 V114 T122 C126 A129 C400 F401 G407 L408 C409	Y110-F405 HydrophobicContact CE1-CB 4.13Å; Y110-F405 HydrophobicContact CE1-CD2 4.2Å; Y110-F405 HydrophobicContact CE1-CG 4.32Å; Y110-F405 VanDerWaalsContact OH-CB 3.29Å; Y110-F405 WeakPolarHBondContact OH-CB 3.3Å; V114-F405 HydrophobicContact CG1-CD1 3.9Å; V114-F405 HydrophobicContact CG1-CE1 4.5Å; V114-F405 HydrophobicContact CG2-CB 4.05Å; V114-F405 HydrophobicContact CG2-CG 4.46Å; T122-F405 HydrophobicContact CG2-CD1 4.23Å; T122-F405 HydrophobicContact CG2-CE1 4.23Å; C126-F405 VanDerWaalsContact CA-CZ 3.49Å; C126-F405 HydrophobicContact CB-CD1 4.17Å; C126-F405 HydrophobicContact CB-CE1 3.69Å; C126-F405 HydrophobicContact CB-CE2 4.32Å; C126-F405 HydrophobicContact CB-CZ 3.78Å; A129-F405 HydrophobicContact CB-CE2 4.31Å; A129-F405 HydrophobicContact CB-CZ 4.4Å; C400-F405 HydrophobicContact CB-CD2 4.35Å; C400-F405 HydrophobicContact CB-CE2 4.01Å; C400-F405 WeakPolarHBondContact O-CD2 3.33Å; C400-F405 PolarHBondContact O-N 3.42Å; F401-F405 AromaticContact CD1-CD2 3.66Å; F401-F405 HydrophobicContact CD1-CD2 3.66Å; F401-F405 AromaticContact CD1-CE2 3.72Å; F401-F405 HydrophobicContact CD1-CE2 3.72Å; F401-F405 HydrophobicContact CE1-CD2 4.18Å; F401-F405 AromaticContact CE1-CE2 3.75Å; F401-F405 HydrophobicContact CE1-CE2 3.75Å; F405-G407 VanDerWaalsContact C-N 3.33Å; F405-G407 PolarHBondContact O-N 3.19Å; F405-L408 PolarHBondContact O-N 3.15Å; F405-C409 WeakPolarHBondContact O-CB 3.4Å; F405-C409 PolarHBondContact O-N 3.01Å; F405-C409 PolarHBondContact O-SG 3.17Å
406	P	96.8	Very high	93.5	Very high	0 Å²	0	23 Å²	23	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-63.3	-38.7	173.8	-22.7	35.9	0	0	0	112.4	I97 L98 F401 C409 L410 M435	I97-P406 HydrophobicContact CB-CB 4.47Å; I97-P406 HydrophobicContact CG2-CB 4.35Å; I97-P406 WeakPolarHBondContact CG2-O 3.25Å; L98-P406 HydrophobicContact CD1-CG 3.94Å; L98-P406 HydrophobicContact CD2-CG 4.36Å; L98-P406 HydrophobicContact CG-CB 4.3Å; L98-P406 HydrophobicContact CG-CG 4.04Å; F401-P406 VanDerWaalsContact O-CD 3.23Å; F401-P406 WeakPolarHBondContact O-CD 3.39Å; F401-P406 WeakPolarHBondContact O-CG 3.47Å; P406-C409 PolarHBondContact O-N 3.47Å; P406-L410 WeakPolarHBondContact O-CB 3.5Å; P406-L410 PolarHBondContact O-N 3.31Å; P406-M435 HydrophobicContact CB-CE 4.35Å
407	G	96.8	Very high	93.1	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-60.6	-45	175.7	0	0	0	0	0	112.3	F403 V404 F405 L410 M411	F403-G407 WeakPolarHBondContact O-CA 3.33Å; F403-G407 PolarHBondContact O-N 2.84Å; V404-G407 PolarHBondContact O-N 3.02Å; F405-G407 VanDerWaalsContact C-N 3.33Å; F405-G407 PolarHBondContact O-N 3.19Å; G407-L410 PolarHBondContact O-N 3.32Å; G407-M411 VanDerWaalsContact O-CG 3.3Å; G407-M411 WeakPolarHBondContact O-CG 3.2Å; G407-M411 PolarHBondContact O-N 3.02Å
408	L	96.6	Very high	91.8	Very high	43 Å²	43	33 Å²	33	23%	0.225	18%	0.184	C	C	.	.	H	α-helix	trans	-61.7	-46.1	173.9	-71.3	174.6	0	0	0	111.6	T122 V404 F405 L410 M411 Q412 V436	T122-L408 HydrophobicContact CG2-CD1 4.01Å; V404-L408 HydrophobicContact CG1-CD1 4.04Å; V404-L408 HydrophobicContact CG1-CG 4.47Å; V404-L408 WeakPolarHBondContact O-CG 3.33Å; V404-L408 PolarHBondContact O-N 2.8Å; F405-L408 PolarHBondContact O-N 3.15Å; L408-L410 VanDerWaalsContact C-N 3.32Å; L408-L410 PolarHBondContact O-N 2.74Å; L408-M411 PolarHBondContact O-N 3.39Å; L408-Q412 WeakPolarHBondContact O-CB 3.41Å; L408-Q412 WeakPolarHBondContact O-CG 3.4Å; L408-Q412 PolarHBondContact O-N 2.85Å; L408-V436 HydrophobicContact CD2-CG1 4.36Å; L408-V436 HydrophobicContact CD2-CG2 3.92Å; L408-V436 HydrophobicContact CG-CG2 3.88Å
409	C	95.6	Very high	90.6	Very high	0 Å²	0	39.2 Å²	39.2	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-59	-43.2	176.8	-73.3	0	0	0	0	111.8	I97 T117 C118 F405 P406 A413	I97-C409 HydrophobicContact CG2-CB 4.35Å; T117-C409 HydrophobicContact CG2-CB 4.16Å; C118-C409 VanDerWaalsContact SG-SG 3.69Å; F405-C409 WeakPolarHBondContact O-CB 3.4Å; F405-C409 PolarHBondContact O-N 3.01Å; F405-C409 PolarHBondContact O-SG 3.17Å; P406-C409 PolarHBondContact O-N 3.47Å; C409-A413 WeakPolarHBondContact O-CB 3.38Å; C409-A413 PolarHBondContact O-N 3.4Å
410	L	95.3	Very high	89.3	Confident	11 Å²	11	46.1 Å²	46.1	6%	0.058	25%	0.252	C	S	.	.	H	α-helix	trans	-64.1	-45.3	177	-179.1	60	0	0	0	111.8	I97 P406 G407 L408 K414 L428 L431	I97-L410 HydrophobicContact CD1-CB 4.1Å; I97-L410 HydrophobicContact CD1-CD2 3.72Å; I97-L410 HydrophobicContact CD1-CG 4.38Å; I97-L410 HydrophobicContact CG1-CB 4.37Å; I97-L410 HydrophobicContact CG1-CD1 4.38Å; I97-L410 HydrophobicContact CG1-CD2 4.28Å; I97-L410 HydrophobicContact CG2-CB 3.95Å; P406-L410 WeakPolarHBondContact O-CB 3.5Å; P406-L410 PolarHBondContact O-N 3.31Å; G407-L410 PolarHBondContact O-N 3.32Å; L408-L410 VanDerWaalsContact C-N 3.32Å; L408-L410 PolarHBondContact O-N 2.74Å; L410-K414 HydrophobicContact CD1-CG 4.13Å; L410-K414 WeakPolarHBondContact O-CB 3.31Å; L410-K414 WeakPolarHBondContact O-CG 3.17Å; L410-K414 PolarHBondContact O-N 3.43Å; L410-L428 HydrophobicContact CD1-CB 4.41Å; L410-L428 VanDerWaalsContact CD2-O 3.24Å; L410-L428 WeakPolarHBondContact CD2-O 3.27Å; L410-L431 HydrophobicContact CD2-CB 4.35Å; L410-L431 HydrophobicContact CD2-CD2 4.12Å; L410-L431 HydrophobicContact CD2-CG 4.24Å
411	M	93.7	Very high	88.4	Confident	40 Å²	40	53.5 Å²	53.5	20%	0.197	28%	0.278	C	S	.	.	H	α-helix	trans	-60.5	-49.6	178	-73.4	175.1	63.4	0	0	111.2	G407 L408 K414 L415 V433 V436	G407-M411 VanDerWaalsContact O-CG 3.3Å; G407-M411 WeakPolarHBondContact O-CG 3.2Å; G407-M411 PolarHBondContact O-N 3.02Å; L408-M411 PolarHBondContact O-N 3.39Å; M411-K414 PolarHBondContact O-N 2.99Å; M411-L415 VanDerWaalsContact O-CB 3.29Å; M411-L415 WeakPolarHBondContact O-CB 3.22Å; M411-L415 WeakPolarHBondContact O-CD1 3.25Å; M411-L415 WeakPolarHBondContact O-CG 3.41Å; M411-L415 PolarHBondContact O-N 3.36Å; M411-V433 HydrophobicContact CE-CG2 3.71Å; M411-V433 HydrophobicContact CG-CG2 4.44Å; M411-V433 HydrophobicContact SD-CB 4.47Å; M411-V433 HydrophobicContact SD-CG2 3.82Å; M411-V436 HydrophobicContact SD-CG2 4Å
412	Q	91.8	Very high	87.9	Confident	89 Å²	89	57.2 Å²	57.2	42%	0.416	30%	0.301	S	S	.	.	H	α-helix	trans	-65.8	-44.2	-179.1	-67.6	-62.4	-18.5	0	0	111.7	T117 L408 K414 L415 S416	T117-Q412 HydrophobicContact CG2-CB 4.1Å; T117-Q412 WeakPolarHBondContact O-CB 3.47Å; L408-Q412 WeakPolarHBondContact O-CB 3.41Å; L408-Q412 WeakPolarHBondContact O-CG 3.4Å; L408-Q412 PolarHBondContact O-N 2.85Å; Q412-K414 VanDerWaalsContact C-N 3.29Å; Q412-K414 PolarHBondContact O-N 2.68Å; Q412-L415 PolarHBondContact O-N 3.46Å; Q412-S416 WeakPolarHBondContact O-CB 3.42Å; Q412-S416 PolarHBondContact O-N 3.16Å; Q412-S416 PolarHBondContact O-OG 2.84Å
413	A	89.1	Confident	87.3	Confident	16 Å²	16	63.1 Å²	63.1	13%	0.132	34%	0.338	C	S	.	.	H	α-helix	trans	-56.4	-44.9	175.3	0	0	0	0	0	111.2	Y100 C409 S416	Y100-A413 HydrophobicContact CE1-CB 4.43Å; C409-A413 WeakPolarHBondContact O-CB 3.38Å; C409-A413 PolarHBondContact O-N 3.4Å; A413-S416 PolarHBondContact O-OG 3.07Å
414	K	89.1	Confident	86.8	Confident	32 Å²	32	66.6 Å²	66.6	14%	0.139	36%	0.362	C	S	.	.	H	α-helix	trans	-77.1	-35.1	-179.1	-70.3	-65.4	170.7	-162.9	0	114.6	L410 M411 Q412 S416 E417 W425 L428 V429	L410-K414 HydrophobicContact CD1-CG 4.13Å; L410-K414 WeakPolarHBondContact O-CB 3.31Å; L410-K414 WeakPolarHBondContact O-CG 3.17Å; L410-K414 PolarHBondContact O-N 3.43Å; M411-K414 PolarHBondContact O-N 2.99Å; Q412-K414 VanDerWaalsContact C-N 3.29Å; Q412-K414 PolarHBondContact O-N 2.68Å; K414-S416 PolarHBondContact O-N 3.17Å; K414-E417 WeakPolarHBondContact CD-OE2 3.24Å; K414-E417 IonicContact NZ-OE1 3.9Å; K414-E417 PolarHBondContact NZ-OE1 2.9Å; K414-E417 IonicContact NZ-OE2 2.84Å; K414-E417 PolarHBondContact NZ-OE2 3.49Å; K414-E417 PolarHBondContact O-N 2.89Å; K414-W425 PolarHBondContact O-NE1 3.24Å; K414-L428 HydrophobicContact CD-CD1 4.34Å; K414-L428 VanDerWaalsContact CE-CD1 3.47Å; K414-L428 HydrophobicContact CG-CB 4.23Å; K414-V429 HydrophobicContact CB-CG2 3.84Å
415	L	87.4	Confident	86.5	Confident	93 Å²	93	66.5 Å²	66.5	49%	0.487	36%	0.359	S	S	.	.	H	α-helix	trans	-69.8	-23.4	175.7	-71.3	167.5	0	0	0	112.3	M411 Q412 E417 W425	M411-L415 VanDerWaalsContact O-CB 3.29Å; M411-L415 WeakPolarHBondContact O-CB 3.22Å; M411-L415 WeakPolarHBondContact O-CD1 3.25Å; M411-L415 WeakPolarHBondContact O-CG 3.41Å; M411-L415 PolarHBondContact O-N 3.36Å; Q412-L415 PolarHBondContact O-N 3.46Å; L415-E417 VanDerWaalsContact C-N 3.33Å; L415-W425 HydrophobicContact CD2-CH2 4.22Å; L415-W425 HydrophobicContact CD2-CZ2 3.99Å
416	S	84.4	Confident	86.2	Confident	88 Å²	88	70.2 Å²	70.2	62%	0.615	38%	0.376	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.7	-15.4	173.9	77.3	0	0	0	0	114.3	Q412 A413 K414 T418	Q412-S416 WeakPolarHBondContact O-CB 3.42Å; Q412-S416 PolarHBondContact O-N 3.16Å; Q412-S416 PolarHBondContact O-OG 2.84Å; A413-S416 PolarHBondContact O-OG 3.07Å; K414-S416 PolarHBondContact O-N 3.17Å; S416-T418 PolarHBondContact O-N 2.76Å
417	E	82.3	Confident	85.9	Confident	75 Å²	75	76.1 Å²	76.1	35%	0.35	41%	0.407	S	S	.	.			trans	-71.3	117.4	176.4	-70.5	176.5	177.6	0	0	109.8	K414 L415 D419	K414-E417 WeakPolarHBondContact CD-OE2 3.24Å; K414-E417 IonicContact NZ-OE1 3.9Å; K414-E417 PolarHBondContact NZ-OE1 2.9Å; K414-E417 IonicContact NZ-OE2 2.84Å; K414-E417 PolarHBondContact NZ-OE2 3.49Å; K414-E417 PolarHBondContact O-N 2.89Å; L415-E417 VanDerWaalsContact C-N 3.33Å; E417-D419 VanDerWaalsContact C-N 3.3Å
418	T	67.4	Low	85.7	Confident	153 Å²	153	78.4 Å²	78.4	94%	0.939	42%	0.419	S	S	*	.			trans	-81.4	-5.2	179.7	14.4	0	0	0	0	114.2	S416	S416-T418 PolarHBondContact O-N 2.76Å
419	D	68.1	Low	85.5	Confident	130 Å²	130	77.5 Å²	77.5	70%	0.695	42%	0.415	S	S	*	.	S	Bend	trans	-89.8	170	-170.7	-144.3	-11.9	0	0	0	113.3	E417 R421	E417-D419 VanDerWaalsContact C-N 3.3Å; D419-R421 PolarHBondContact O-N 3.17Å
420	I	64.8	Low	85.4	Confident	145 Å²	145	81.6 Å²	81.6	74%	0.744	44%	0.44	S	S	*	.			trans	-50.3	120.6	-173.9	-61.2	165.9	0	0	0	111.4	T422	I420-T422 PolarHBondContact O-N 3.24Å
421	R	77.9	Confident	85.4	Confident	169 Å²	169	83.3 Å²	83.3	64%	0.638	45%	0.449	S	S	*	.			trans	-67.6	92.6	179.9	-65.2	179.1	-177.9	169	0.1	111	D419 W425	D419-R421 PolarHBondContact O-N 3.17Å; R421-W425 HydrophobicContact CB-CD2 4.35Å; R421-W425 HydrophobicContact CB-CE3 4.13Å; R421-W425 HydrophobicContact CG-CD2 4.1Å; R421-W425 HydrophobicContact CG-CE3 4.05Å; R421-W425 HydrophobicContact CG-CZ3 4.3Å
422	T	82.9	Confident	85.5	Confident	79 Å²	79	81.4 Å²	81.4	49%	0.485	44%	0.44	S	S	.	.			trans	-74.3	164.2	174.2	60	0	0	0	0	111.7	I420 S424 W425 H426	I420-T422 PolarHBondContact O-N 3.24Å; T422-S424 PolarHBondContact O-N 2.85Å; T422-W425 VanDerWaalsContact O-CB 3.27Å; T422-W425 WeakPolarHBondContact O-CB 3.41Å; T422-W425 PolarHBondContact O-N 3.25Å; T422-W425 PolarHBondContact OG1-N 3.35Å; T422-H426 PolarHBondContact O-N 3.32Å
423	T	84.5	Confident	85.7	Confident	124 Å²	124	80.2 Å²	80.2	76%	0.761	44%	0.438	S	S	*	.	H	α-helix	trans	-56.3	-33.6	173.5	-46.5	0	0	0	0	112.6	W425 H426 L427	T423-W425 VanDerWaalsContact C-N 3.34Å; T423-H426 PolarHBondContact O-N 3.49Å; T423-L427 PolarHBondContact O-N 3.46Å; T423-L427 VanDerWaalsContact O-N 3.09Å
424	S	85.8	Confident	86.1	Confident	72 Å²	72	82.1 Å²	82.1	50%	0.503	45%	0.449	S	S	.	.	H	α-helix	trans	-64.5	-37.7	175.3	-175.7	0	0	0	0	112.2	T422 L427 L428	T422-S424 PolarHBondContact O-N 2.85Å; S424-L427 PolarHBondContact O-N 3.39Å; S424-L428 WeakPolarHBondContact O-CG 3.27Å; S424-L428 PolarHBondContact O-N 3.22Å
425	W	90.4	Very high	86.4	Confident	22 Å²	22	80.6 Å²	80.6	8%	0.083	44%	0.442	C	S	.	.	H	α-helix	trans	-60.7	-48.6	174.9	-178.4	96.4	0	0	0	111.2	K414 L415 R421 T422 T423 L427 L428 V429	K414-W425 PolarHBondContact O-NE1 3.24Å; L415-W425 HydrophobicContact CD2-CH2 4.22Å; L415-W425 HydrophobicContact CD2-CZ2 3.99Å; R421-W425 HydrophobicContact CB-CD2 4.35Å; R421-W425 HydrophobicContact CB-CE3 4.13Å; R421-W425 HydrophobicContact CG-CD2 4.1Å; R421-W425 HydrophobicContact CG-CE3 4.05Å; R421-W425 HydrophobicContact CG-CZ3 4.3Å; T422-W425 VanDerWaalsContact O-CB 3.27Å; T422-W425 WeakPolarHBondContact O-CB 3.41Å; T422-W425 PolarHBondContact O-N 3.25Å; T422-W425 PolarHBondContact OG1-N 3.35Å; T423-W425 VanDerWaalsContact C-N 3.34Å; W425-L427 VanDerWaalsContact C-N 3.32Å; W425-L427 PolarHBondContact O-N 3.02Å; W425-L428 PolarHBondContact O-N 3.3Å; W425-V429 HydrophobicContact CD2-CG2 4.01Å; W425-V429 HydrophobicContact CE3-CG2 4.16Å; W425-V429 HydrophobicContact CH2-CG2 3.91Å; W425-V429 HydrophobicContact CZ2-CG2 3.78Å; W425-V429 HydrophobicContact CZ3-CG2 4.1Å; W425-V429 WeakPolarHBondContact O-CG2 3.47Å; W425-V429 PolarHBondContact O-N 3.49Å
426	H	88.8	Confident	86.9	Confident	94 Å²	94	77.7 Å²	77.7	44%	0.435	43%	0.428	S	S	.	.	H	α-helix	trans	-60	-42.2	177.9	-74.9	-72.6	0	0	0	112	T422 T423 L428 V429 V430	T422-H426 PolarHBondContact O-N 3.32Å; T423-H426 PolarHBondContact O-N 3.49Å; H426-L428 PolarHBondContact O-N 3.5Å; H426-V429 PolarHBondContact O-N 3.03Å; H426-V430 WeakPolarHBondContact O-CB 3.5Å; H426-V430 VanDerWaalsContact O-CG2 3.26Å; H426-V430 WeakPolarHBondContact O-CG2 3.42Å; H426-V430 PolarHBondContact O-N 3.05Å
427	L	91.1	Very high	87.4	Confident	123 Å²	123	77.4 Å²	77.4	64%	0.644	42%	0.423	S	S	*	.	H	α-helix	trans	-61	-43.9	177.7	-175.9	67.7	0	0	0	112.2	T423 S424 W425 V430 L431	T423-L427 PolarHBondContact O-N 3.46Å; T423-L427 VanDerWaalsContact O-N 3.09Å; S424-L427 PolarHBondContact O-N 3.39Å; W425-L427 VanDerWaalsContact C-N 3.32Å; W425-L427 PolarHBondContact O-N 3.02Å; L427-V430 PolarHBondContact O-N 2.81Å; L427-L431 WeakPolarHBondContact O-CB 3.36Å; L427-L431 PolarHBondContact O-N 3.35Å
428	L	92.1	Very high	87.9	Confident	49 Å²	49	75.1 Å²	75.1	26%	0.257	41%	0.413	S	S	.	.	H	α-helix	trans	-70.1	-36.6	-179.8	-69.8	172.4	0	0	0	112.5	L410 K414 S424 W425 H426 L431 G432	L410-L428 HydrophobicContact CD1-CB 4.41Å; L410-L428 VanDerWaalsContact CD2-O 3.24Å; L410-L428 WeakPolarHBondContact CD2-O 3.27Å; K414-L428 HydrophobicContact CD-CD1 4.34Å; K414-L428 VanDerWaalsContact CE-CD1 3.47Å; K414-L428 HydrophobicContact CG-CB 4.23Å; S424-L428 WeakPolarHBondContact O-CG 3.27Å; S424-L428 PolarHBondContact O-N 3.22Å; W425-L428 PolarHBondContact O-N 3.3Å; H426-L428 PolarHBondContact O-N 3.5Å; L428-L431 HydrophobicContact CD2-CD2 4.5Å; L428-L431 PolarHBondContact O-N 3.39Å; L428-G432 PolarHBondContact O-N 3.48Å
429	V	92.7	Very high	89.2	Confident	23 Å²	23	67.9 Å²	67.9	14%	0.139	37%	0.368	C	S	.	.	H	α-helix	trans	-65.9	-44.3	173.2	173.9	0	0	0	0	110.8	K414 W425 H426 L431 G432 V433	K414-V429 HydrophobicContact CB-CG2 3.84Å; W425-V429 HydrophobicContact CD2-CG2 4.01Å; W425-V429 HydrophobicContact CE3-CG2 4.16Å; W425-V429 HydrophobicContact CH2-CG2 3.91Å; W425-V429 HydrophobicContact CZ2-CG2 3.78Å; W425-V429 HydrophobicContact CZ3-CG2 4.1Å; W425-V429 WeakPolarHBondContact O-CG2 3.47Å; W425-V429 PolarHBondContact O-N 3.49Å; H426-V429 PolarHBondContact O-N 3.03Å; V429-L431 VanDerWaalsContact C-N 3.32Å; V429-L431 PolarHBondContact O-N 3.1Å; V429-G432 PolarHBondContact O-N 3.27Å; V429-V433 HydrophobicContact CG1-CG2 4.49Å; V429-V433 WeakPolarHBondContact O-CG2 3.45Å; V429-V433 PolarHBondContact O-N 3.03Å
430	V	94.5	Very high	90.5	Very high	87 Å²	87	64.1 Å²	64.1	53%	0.527	36%	0.355	S	S	.	.	H	α-helix	trans	-61.4	-40.8	175.8	169.1	0	0	0	0	111.3	H426 L427 V433 T434	H426-V430 WeakPolarHBondContact O-CB 3.5Å; H426-V430 VanDerWaalsContact O-CG2 3.26Å; H426-V430 WeakPolarHBondContact O-CG2 3.42Å; H426-V430 PolarHBondContact O-N 3.05Å; L427-V430 PolarHBondContact O-N 2.81Å; V430-V433 PolarHBondContact O-N 3.27Å; V430-T434 WeakPolarHBondContact O-CB 3.37Å; V430-T434 PolarHBondContact O-N 2.95Å; V430-T434 PolarHBondContact O-OG1 3.37Å
431	L	95.4	Very high	91.8	Very high	47 Å²	47	62.1 Å²	62.1	25%	0.246	34%	0.341	C	S	.	.	H	α-helix	trans	-59.6	-47.7	173.3	178.6	63.4	0	0	0	111.1	F90 L410 L427 L428 V429 V433 T434 M435	F90-L431 HydrophobicContact CD1-CD1 4.5Å; F90-L431 HydrophobicContact CE1-CD1 4.2Å; L410-L431 HydrophobicContact CD2-CB 4.35Å; L410-L431 HydrophobicContact CD2-CD2 4.12Å; L410-L431 HydrophobicContact CD2-CG 4.24Å; L427-L431 WeakPolarHBondContact O-CB 3.36Å; L427-L431 PolarHBondContact O-N 3.35Å; L428-L431 HydrophobicContact CD2-CD2 4.5Å; L428-L431 PolarHBondContact O-N 3.39Å; V429-L431 VanDerWaalsContact C-N 3.32Å; V429-L431 PolarHBondContact O-N 3.1Å; L431-V433 PolarHBondContact O-N 2.86Å; L431-T434 PolarHBondContact O-N 3.07Å; L431-M435 HydrophobicContact CD1-CG 4.39Å; L431-M435 HydrophobicContact CD1-SD 4.47Å; L431-M435 HydrophobicContact CG-SD 4.32Å; L431-M435 WeakPolarHBondContact O-CG 3.28Å; L431-M435 PolarHBondContact O-N 2.92Å
432	G	95.6	Very high	92.4	Very high	0 Å²	0	54.2 Å²	54.2	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-58.9	-47.6	177.3	0	0	0	0	0	112.7	L428 V429 T434 M435 V436	L428-G432 PolarHBondContact O-N 3.48Å; V429-G432 PolarHBondContact O-N 3.27Å; G432-T434 VanDerWaalsContact C-N 3.34Å; G432-T434 PolarHBondContact O-N 3Å; G432-M435 PolarHBondContact O-N 3.34Å; G432-V436 WeakPolarHBondContact O-CG2 3.24Å; G432-V436 PolarHBondContact O-N 3.49Å
433	V	96.4	Very high	92.9	Very high	63 Å²	63	53.9 Å²	53.9	38%	0.382	30%	0.304	S	S	.	.	H	α-helix	trans	-60	-44.9	175.9	172.4	0	0	0	0	111	M411 V429 V430 L431 M435 V436 T437	M411-V433 HydrophobicContact CE-CG2 3.71Å; M411-V433 HydrophobicContact CG-CG2 4.44Å; M411-V433 HydrophobicContact SD-CB 4.47Å; M411-V433 HydrophobicContact SD-CG2 3.82Å; V429-V433 HydrophobicContact CG1-CG2 4.49Å; V429-V433 WeakPolarHBondContact O-CG2 3.45Å; V429-V433 PolarHBondContact O-N 3.03Å; V430-V433 PolarHBondContact O-N 3.27Å; L431-V433 PolarHBondContact O-N 2.86Å; V433-M435 VanDerWaalsContact C-N 3.34Å; V433-M435 PolarHBondContact O-N 3.29Å; V433-V436 PolarHBondContact O-N 3.45Å; V433-T437 HydrophobicContact CG1-CG2 4.28Å; V433-T437 WeakPolarHBondContact O-CG2 3.37Å; V433-T437 PolarHBondContact O-N 2.95Å; V433-T437 PolarHBondContact O-OG1 3.49Å; V433-T437 VanDerWaalsContact O-OG1 3.07Å
434	T	96	Very high	93.2	Very high	57 Å²	57	49.4 Å²	49.4	35%	0.35	28%	0.282	S	S	.	.	H	α-helix	trans	-62.8	-40.7	178.8	-56.5	0	0	0	0	111.6	F90 V430 L431 G432 T437 L438	F90-T434 HydrophobicContact CE1-CG2 4.35Å; F90-T434 HydrophobicContact CZ-CG2 4.39Å; V430-T434 WeakPolarHBondContact O-CB 3.37Å; V430-T434 PolarHBondContact O-N 2.95Å; V430-T434 PolarHBondContact O-OG1 3.37Å; L431-T434 PolarHBondContact O-N 3.07Å; G432-T434 VanDerWaalsContact C-N 3.34Å; G432-T434 PolarHBondContact O-N 3Å; T434-T437 PolarHBondContact O-OG1 3.37Å; T434-T437 VanDerWaalsContact O-OG1 3.12Å; T434-L438 WeakPolarHBondContact O-CB 3.37Å; T434-L438 PolarHBondContact O-N 3.13Å
435	M	96.3	Very high	93.3	Very high	0 Å²	0	48.7 Å²	48.7	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-62.6	-47.8	175	-73.5	-176.4	83.6	0	0	110.9	F90 I97 I402 F403 P406 L431 G432 V433 T437 G439	F90-M435 HydrophobicContact CB-CE 4.33Å; F90-M435 HydrophobicContact CD1-CE 4.42Å; F90-M435 HydrophobicContact CD1-CG 3.59Å; F90-M435 HydrophobicContact CD1-SD 4.34Å; F90-M435 HydrophobicContact CE1-CG 4.01Å; I97-M435 HydrophobicContact CD1-SD 3.92Å; I402-M435 VanDerWaalsContact O-CE 3.31Å; I402-M435 WeakPolarHBondContact O-CE 3.26Å; F403-M435 WeakPolarHBondContact CB-O 3.24Å; P406-M435 HydrophobicContact CB-CE 4.35Å; L431-M435 HydrophobicContact CD1-CG 4.39Å; L431-M435 HydrophobicContact CD1-SD 4.47Å; L431-M435 HydrophobicContact CG-SD 4.32Å; L431-M435 WeakPolarHBondContact O-CG 3.28Å; L431-M435 PolarHBondContact O-N 2.92Å; G432-M435 PolarHBondContact O-N 3.34Å; V433-M435 VanDerWaalsContact C-N 3.34Å; V433-M435 PolarHBondContact O-N 3.29Å; M435-T437 PolarHBondContact O-N 2.92Å; M435-G439 PolarHBondContact O-N 3.47Å
436	V	97.1	Very high	93	Very high	31 Å²	31	47.9 Å²	47.9	19%	0.188	27%	0.27	C	S	.	.	H	α-helix	trans	-62.9	-45.8	-179.7	175.5	0	0	0	0	111.7	L408 M411 G432 V433 G439 A440	L408-V436 HydrophobicContact CD2-CG1 4.36Å; L408-V436 HydrophobicContact CD2-CG2 3.92Å; L408-V436 HydrophobicContact CG-CG2 3.88Å; M411-V436 HydrophobicContact SD-CG2 4Å; G432-V436 WeakPolarHBondContact O-CG2 3.24Å; G432-V436 PolarHBondContact O-N 3.49Å; V433-V436 PolarHBondContact O-N 3.45Å; V436-G439 PolarHBondContact O-N 3.47Å; V436-A440 VanDerWaalsContact O-CB 3.24Å; V436-A440 WeakPolarHBondContact O-CB 3.41Å; V436-A440 PolarHBondContact O-N 3.18Å
437	T	95.8	Very high	92.9	Very high	83 Å²	83	44.8 Å²	44.8	51%	0.509	26%	0.257	S	S	.	.	H	α-helix	trans	-66.6	-45.4	-178.6	54.7	0	0	0	0	111.9	V433 T434 M435 F441	V433-T437 HydrophobicContact CG1-CG2 4.28Å; V433-T437 WeakPolarHBondContact O-CG2 3.37Å; V433-T437 PolarHBondContact O-N 2.95Å; V433-T437 PolarHBondContact O-OG1 3.49Å; V433-T437 VanDerWaalsContact O-OG1 3.07Å; T434-T437 PolarHBondContact O-OG1 3.37Å; T434-T437 VanDerWaalsContact O-OG1 3.12Å; M435-T437 PolarHBondContact O-N 2.92Å; T437-F441 VanDerWaalsContact O-CB 3.32Å; T437-F441 WeakPolarHBondContact O-CB 3.38Å; T437-F441 PolarHBondContact O-N 3Å
438	L	93.5	Very high	92.7	Very high	27 Å²	27	42.5 Å²	42.5	14%	0.141	25%	0.252	C	S	.	.	H	α-helix	trans	-63.5	-45.6	176.9	-177.9	62.7	0	0	0	111.1	F86 M87 F90 F403 T434 F441 I442	F86-L438 HydrophobicContact CE1-CD2 3.92Å; F86-L438 HydrophobicContact CZ-CD2 4.08Å; M87-L438 HydrophobicContact CE-CD2 4.26Å; F90-L438 HydrophobicContact CD2-CD2 4.3Å; F90-L438 HydrophobicContact CE2-CD2 3.95Å; F90-L438 HydrophobicContact CZ-CD2 4.12Å; F403-L438 HydrophobicContact CD1-CD2 4.1Å; F403-L438 HydrophobicContact CD1-CG 4.47Å; F403-L438 HydrophobicContact CE1-CD2 3.77Å; F403-L438 HydrophobicContact CE1-CG 4.45Å; T434-L438 WeakPolarHBondContact O-CB 3.37Å; T434-L438 PolarHBondContact O-N 3.13Å; L438-F441 PolarHBondContact O-N 2.99Å; L438-I442 HydrophobicContact CD1-CD1 4Å; L438-I442 HydrophobicContact CD1-CG1 4.3Å; L438-I442 HydrophobicContact CG-CD1 3.82Å; L438-I442 HydrophobicContact CG-CG1 4.49Å; L438-I442 VanDerWaalsContact O-CG1 3.24Å; L438-I442 WeakPolarHBondContact O-CG1 3.31Å; L438-I442 PolarHBondContact O-N 3.48Å
439	G	93.8	Very high	92.3	Very high	0 Å²	0	42 Å²	42	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-61.7	-45.5	178.3	0	0	0	0	0	113	F403 M435 V436 F441 I442 F443	F403-G439 VanDerWaalsContact CB-CA 3.47Å; M435-G439 PolarHBondContact O-N 3.47Å; V436-G439 PolarHBondContact O-N 3.47Å; G439-F441 VanDerWaalsContact C-N 3.34Å; G439-I442 PolarHBondContact O-N 3.34Å; G439-F443 WeakPolarHBondContact O-CB 3.46Å; G439-F443 PolarHBondContact O-N 3.31Å
440	A	94.3	Very high	91.8	Very high	52 Å²	52	41.4 Å²	41.4	43%	0.43	25%	0.247	S	C	.	.	H	α-helix	trans	-64.4	-39.4	176.9	0	0	0	0	0	111.8	V436 G444	V436-A440 VanDerWaalsContact O-CB 3.24Å; V436-A440 WeakPolarHBondContact O-CB 3.41Å; V436-A440 PolarHBondContact O-N 3.18Å; A440-G444 PolarHBondContact O-N 3.44Å
441	F	92.8	Very high	91.2	Very high	103 Å²	103	42 Å²	42	45%	0.452	25%	0.246	S	C	.	.	H	α-helix	trans	-63	-49.5	174.8	175.4	-101.4	0	0	0	111.8	F241 T437 L438 G439 G444 L445	F241-F441 AromaticContact CD1-CE1 3.75Å; F241-F441 HydrophobicContact CD1-CE1 3.75Å; F241-F441 HydrophobicContact CD2-CE1 4.13Å; F241-F441 HydrophobicContact CD2-CZ 4.36Å; F241-F441 HydrophobicContact CE1-CD1 4.33Å; F241-F441 AromaticContact CE1-CE1 3.64Å; F241-F441 HydrophobicContact CE1-CE1 3.64Å; F241-F441 HydrophobicContact CE2-CE1 4.03Å; F241-F441 HydrophobicContact CE2-CZ 4.25Å; F241-F441 HydrophobicContact CG-CE1 4.04Å; F241-F441 AromaticContact CZ-CE1 3.8Å; F241-F441 HydrophobicContact CZ-CE1 3.8Å; F241-F441 HydrophobicContact CZ-CZ 4.38Å; T437-F441 VanDerWaalsContact O-CB 3.32Å; T437-F441 WeakPolarHBondContact O-CB 3.38Å; T437-F441 PolarHBondContact O-N 3Å; L438-F441 PolarHBondContact O-N 2.99Å; G439-F441 VanDerWaalsContact C-N 3.34Å; F441-G444 PolarHBondContact O-N 2.9Å; F441-L445 HydrophobicContact CE1-CD2 4.15Å; F441-L445 HydrophobicContact CZ-CD2 4.15Å; F441-L445 VanDerWaalsContact O-CB 3.25Å; F441-L445 WeakPolarHBondContact O-CB 3.48Å; F441-L445 PolarHBondContact O-N 3.17Å
442	I	91.1	Very high	90.7	Very high	2 Å²	2	47 Å²	47	1%	0.01	26%	0.262	C	S	.	.	H	α-helix	trans	-60.2	-49.8	178.2	-66	167	0	0	0	109.8	M87 M244 A399 F403 L438 G439 G444 L445 T446	M87-I442 HydrophobicContact CE-CD1 4.28Å; M244-I442 HydrophobicContact CB-CG2 4.22Å; M244-I442 HydrophobicContact SD-CD1 3.52Å; M244-I442 VanDerWaalsContact SD-CD1 3.52Å; M244-I442 HydrophobicContact SD-CG1 3.66Å; A399-I442 HydrophobicContact CB-CB 4.06Å; A399-I442 HydrophobicContact CB-CG2 3.57Å; F403-I442 HydrophobicContact CE2-CD1 4.22Å; F403-I442 HydrophobicContact CZ-CD1 4.45Å; L438-I442 HydrophobicContact CD1-CD1 4Å; L438-I442 HydrophobicContact CD1-CG1 4.3Å; L438-I442 HydrophobicContact CG-CD1 3.82Å; L438-I442 HydrophobicContact CG-CG1 4.49Å; L438-I442 VanDerWaalsContact O-CG1 3.24Å; L438-I442 WeakPolarHBondContact O-CG1 3.31Å; L438-I442 PolarHBondContact O-N 3.48Å; G439-I442 PolarHBondContact O-N 3.34Å; I442-G444 PolarHBondContact O-N 3.28Å; I442-L445 PolarHBondContact O-N 2.89Å; I442-T446 HydrophobicContact CG2-CG2 4.11Å; I442-T446 VanDerWaalsContact O-CB 3.24Å; I442-T446 WeakPolarHBondContact O-CB 3.47Å; I442-T446 WeakPolarHBondContact O-CG2 3.28Å; I442-T446 PolarHBondContact O-N 2.97Å; I442-T446 PolarHBondContact O-OG1 3.25Å
443	F	92.2	Very high	89.7	Confident	72 Å²	72	51.4 Å²	51.4	32%	0.316	28%	0.283	S	S	.	.	H	α-helix	trans	-58	-48.4	178.5	174.1	-108.9	0	0	0	112.3	G396 L397 C400 G439 T446 T447	G396-F443 WeakPolarHBondContact O-CD2 3.25Å; L397-F443 HydrophobicContact CD2-CE2 3.74Å; L397-F443 HydrophobicContact CD2-CZ 4.44Å; L397-F443 HydrophobicContact CG-CE2 4.35Å; C400-F443 VanDerWaalsContact SG-CG 3.53Å; G439-F443 WeakPolarHBondContact O-CB 3.46Å; G439-F443 PolarHBondContact O-N 3.31Å; F443-T446 PolarHBondContact O-N 3.37Å; F443-T446 PolarHBondContact O-OG1 3.37Å; F443-T447 WeakPolarHBondContact CE2-OG1 3.35Å; F443-T447 VanDerWaalsContact O-CB 3.25Å; F443-T447 WeakPolarHBondContact O-CB 3.49Å; F443-T447 PolarHBondContact O-N 3.21Å; F443-T447 PolarHBondContact O-OG1 3.12Å
444	G	91.8	Very high	88.7	Confident	30 Å²	30	52.8 Å²	52.8	31%	0.309	29%	0.288	S	S	.	.	H	α-helix	trans	-63.5	-47.7	-179.2	0	0	0	0	0	112.6	A440 F441 I442 T446 S448	A440-G444 PolarHBondContact O-N 3.44Å; F441-G444 PolarHBondContact O-N 2.9Å; I442-G444 PolarHBondContact O-N 3.28Å; G444-T446 VanDerWaalsContact C-N 3.34Å; G444-T446 PolarHBondContact O-N 2.89Å; G444-S448 VanDerWaalsContact O-CB 3.25Å; G444-S448 WeakPolarHBondContact O-CB 3.21Å; G444-S448 PolarHBondContact O-N 3.45Å; G444-S448 PolarHBondContact O-OG 2.95Å
445	L	87.9	Confident	87.8	Confident	57 Å²	57	55.5 Å²	55.5	30%	0.298	31%	0.305	S	S	.	.	H	α-helix	trans	-60.5	-45.3	179.1	179	68.5	0	0	0	111.6	F241 F441 I442 S448 N449	F241-L445 HydrophobicContact CB-CD2 3.39Å; F241-L445 HydrophobicContact CD2-CD2 4.45Å; F241-L445 HydrophobicContact CG-CD2 4.01Å; F441-L445 HydrophobicContact CE1-CD2 4.15Å; F441-L445 HydrophobicContact CZ-CD2 4.15Å; F441-L445 VanDerWaalsContact O-CB 3.25Å; F441-L445 WeakPolarHBondContact O-CB 3.48Å; F441-L445 PolarHBondContact O-N 3.17Å; I442-L445 PolarHBondContact O-N 2.89Å; L445-S448 PolarHBondContact O-N 2.97Å; L445-N449 WeakPolarHBondContact O-CB 3.4Å; L445-N449 PolarHBondContact O-N 3.04Å
446	T	84.8	Confident	86.9	Confident	5 Å²	5	59.6 Å²	59.6	3%	0.031	33%	0.329	C	S	.	.	H	α-helix	trans	-79	-37.3	-169	57.9	0	0	0	0	111.6	P245 G396 I442 F443 G444 N449 S450	P245-T446 HydrophobicContact CB-CG2 4.46Å; P245-T446 HydrophobicContact CG-CG2 3.09Å; G396-T446 WeakPolarHBondContact CA-OG1 3.04Å; I442-T446 HydrophobicContact CG2-CG2 4.11Å; I442-T446 VanDerWaalsContact O-CB 3.24Å; I442-T446 WeakPolarHBondContact O-CB 3.47Å; I442-T446 WeakPolarHBondContact O-CG2 3.28Å; I442-T446 PolarHBondContact O-N 2.97Å; I442-T446 PolarHBondContact O-OG1 3.25Å; F443-T446 PolarHBondContact O-N 3.37Å; F443-T446 PolarHBondContact O-OG1 3.37Å; G444-T446 VanDerWaalsContact C-N 3.34Å; G444-T446 PolarHBondContact O-N 2.89Å; T446-N449 PolarHBondContact O-N 2.93Å; T446-S450 WeakPolarHBondContact O-CB 3.42Å; T446-S450 PolarHBondContact O-N 3.43Å; T446-S450 PolarHBondContact O-OG 3.34Å
447	T	85.2	Confident	84.8	Confident	29 Å²	29	66.2 Å²	66.2	18%	0.178	36%	0.364	C	S	.	.	H	α-helix	trans	-62.7	-45.7	169.5	-53.3	0	0	0	0	110.5	F443 N449 S450 I451	F443-T447 WeakPolarHBondContact CE2-OG1 3.35Å; F443-T447 VanDerWaalsContact O-CB 3.25Å; F443-T447 WeakPolarHBondContact O-CB 3.49Å; F443-T447 PolarHBondContact O-N 3.21Å; F443-T447 PolarHBondContact O-OG1 3.12Å; T447-N449 PolarHBondContact O-N 3.3Å; T447-S450 PolarHBondContact O-N 2.88Å; T447-I451 HydrophobicContact CG2-CD1 3.91Å; T447-I451 VanDerWaalsContact O-CG1 3.27Å; T447-I451 WeakPolarHBondContact O-CG1 3.47Å; T447-I451 PolarHBondContact O-N 2.93Å
448	S	87.9	Confident	84.3	Confident	76 Å²	76	65.4 Å²	65.4	53%	0.531	36%	0.356	S	S	.	.	H	α-helix	trans	-63.8	-42.7	179.1	-57.4	0	0	0	0	112	G444 L445 I451 Y452	G444-S448 VanDerWaalsContact O-CB 3.25Å; G444-S448 WeakPolarHBondContact O-CB 3.21Å; G444-S448 PolarHBondContact O-N 3.45Å; G444-S448 PolarHBondContact O-OG 2.95Å; L445-S448 PolarHBondContact O-N 2.97Å; S448-I451 PolarHBondContact O-N 2.87Å; S448-Y452 WeakPolarHBondContact O-CB 3.39Å; S448-Y452 PolarHBondContact O-N 3.24Å
449	N	83.9	Confident	83.8	Confident	39 Å²	39	67.4 Å²	67.4	21%	0.209	37%	0.368	C	S	.	.	H	α-helix	trans	-67.1	-40.8	178.8	-167.3	15.2	0	0	0	111.6	N242 L445 T446 T447 Y452 Q453	N242-N449 PolarHBondContact OD1-ND2 3.26Å; L445-N449 WeakPolarHBondContact O-CB 3.4Å; L445-N449 PolarHBondContact O-N 3.04Å; T446-N449 PolarHBondContact O-N 2.93Å; T447-N449 PolarHBondContact O-N 3.3Å; N449-Y452 PolarHBondContact O-N 2.91Å; N449-Q453 WeakPolarHBondContact O-CG 3.4Å; N449-Q453 PolarHBondContact O-N 2.99Å
450	S	80.8	Confident	83.2	Confident	10 Å²	10	71.2 Å²	71.2	7%	0.07	39%	0.388	C	S	.	.	H	α-helix	trans	-61.3	-47	176.2	-56.6	0	0	0	0	111.2	S392 T446 T447 Y452 Q453 D454	S392-S450 WeakPolarHBondContact CB-OG 2.81Å; S392-S450 PolarHBondContact OG-OG 3.23Å; T446-S450 WeakPolarHBondContact O-CB 3.42Å; T446-S450 PolarHBondContact O-N 3.43Å; T446-S450 PolarHBondContact O-OG 3.34Å; T447-S450 PolarHBondContact O-N 2.88Å; S450-Y452 VanDerWaalsContact C-N 3.33Å; S450-Y452 PolarHBondContact O-N 3.29Å; S450-Q453 PolarHBondContact O-N 3.35Å; S450-D454 PolarHBondContact O-N 2.88Å
451	I	82.8	Confident	82.6	Confident	100 Å²	100	72.3 Å²	72.3	51%	0.513	39%	0.386	S	S	.	.	H	α-helix	trans	-61.8	-43	176.4	-65.8	166.2	0	0	0	110.8	T447 S448 Q453 D454 V455	T447-I451 HydrophobicContact CG2-CD1 3.91Å; T447-I451 VanDerWaalsContact O-CG1 3.27Å; T447-I451 WeakPolarHBondContact O-CG1 3.47Å; T447-I451 PolarHBondContact O-N 2.93Å; S448-I451 PolarHBondContact O-N 2.87Å; I451-Q453 PolarHBondContact O-N 2.61Å; I451-D454 PolarHBondContact O-N 3.45Å; I451-V455 HydrophobicContact CG2-CG2 4.15Å; I451-V455 WeakPolarHBondContact O-CB 3.22Å; I451-V455 VanDerWaalsContact O-CG2 3.23Å; I451-V455 WeakPolarHBondContact O-CG2 3.4Å; I451-V455 PolarHBondContact O-N 3.28Å
452	Y	84.3	Confident	82	Confident	150 Å²	150	70.4 Å²	70.4	59%	0.588	38%	0.382	S	S	*	.	H	α-helix	trans	-61.4	-44.9	178.9	179.7	-96.3	0	0	0	111.8	S448 N449 S450 D454 V455 V456	S448-Y452 WeakPolarHBondContact O-CB 3.39Å; S448-Y452 PolarHBondContact O-N 3.24Å; N449-Y452 PolarHBondContact O-N 2.91Å; S450-Y452 VanDerWaalsContact C-N 3.33Å; S450-Y452 PolarHBondContact O-N 3.29Å; Y452-D454 VanDerWaalsContact C-N 3.32Å; Y452-D454 PolarHBondContact O-N 2.83Å; Y452-V455 PolarHBondContact O-N 2.8Å; Y452-V456 HydrophobicContact CD1-CG2 4.42Å; Y452-V456 HydrophobicContact CD2-CG2 3.99Å; Y452-V456 HydrophobicContact CE1-CG2 4.13Å; Y452-V456 HydrophobicContact CE2-CG2 3.68Å; Y452-V456 HydrophobicContact CG-CG2 4.36Å; Y452-V456 WeakPolarHBondContact O-CB 3.28Å; Y452-V456 VanDerWaalsContact O-CG2 3.29Å; Y452-V456 WeakPolarHBondContact O-CG2 3.43Å; Y452-V456 PolarHBondContact O-N 3.18Å
453	Q	74.9	Confident	81.4	Confident	94 Å²	94	74.9 Å²	74.9	44%	0.439	41%	0.406	S	S	.	.	H	α-helix	trans	-64.3	-35.9	178.3	-73.1	-178.6	-3.8	0	0	112.8	N449 S450 I451 N457	N449-Q453 WeakPolarHBondContact O-CG 3.4Å; N449-Q453 PolarHBondContact O-N 2.99Å; S450-Q453 PolarHBondContact O-N 3.35Å; I451-Q453 PolarHBondContact O-N 2.61Å; Q453-N457 WeakPolarHBondContact O-CB 3.4Å; Q453-N457 PolarHBondContact O-N 3.08Å; Q453-N457 PolarHBondContact O-ND2 2.61Å
454	D	75.4	Confident	80.6	Confident	92 Å²	92	75.1 Å²	75.1	49%	0.492	41%	0.413	S	S	.	.	H	α-helix	trans	-79	-22.3	178.5	-73.3	-20.8	0	0	0	113.7	R389 S450 I451 Y452	R389-D454 IonicContact NE-OD1 2.81Å; S450-D454 PolarHBondContact O-N 2.88Å; I451-D454 PolarHBondContact O-N 3.45Å; Y452-D454 VanDerWaalsContact C-N 3.32Å; Y452-D454 PolarHBondContact O-N 2.83Å
455	V	78.3	Confident	79.7	Confident	114 Å²	114	78.6 Å²	78.6	69%	0.691	42%	0.421	S	S	*	.	H	α-helix	trans	-87.4	-32.5	177.5	170.3	0	0	0	0	111.7	I451 Y452	I451-V455 HydrophobicContact CG2-CG2 4.15Å; I451-V455 WeakPolarHBondContact O-CB 3.22Å; I451-V455 VanDerWaalsContact O-CG2 3.23Å; I451-V455 WeakPolarHBondContact O-CG2 3.4Å; I451-V455 PolarHBondContact O-N 3.28Å; Y452-V455 PolarHBondContact O-N 2.8Å
456	V	76.2	Confident	79	Confident	85 Å²	85	80.4 Å²	80.4	52%	0.515	43%	0.431	S	S	.	.	H	α-helix	trans	-90.5	-27.9	-174.5	175.8	0	0	0	0	112.8	Y452	Y452-V456 HydrophobicContact CD1-CG2 4.42Å; Y452-V456 HydrophobicContact CD2-CG2 3.99Å; Y452-V456 HydrophobicContact CE1-CG2 4.13Å; Y452-V456 HydrophobicContact CE2-CG2 3.68Å; Y452-V456 HydrophobicContact CG-CG2 4.36Å; Y452-V456 WeakPolarHBondContact O-CB 3.28Å; Y452-V456 VanDerWaalsContact O-CG2 3.29Å; Y452-V456 WeakPolarHBondContact O-CG2 3.43Å; Y452-V456 PolarHBondContact O-N 3.18Å
457	N	53.8	Low	78.5	Confident	171 Å²	171	87.3 Å²	87.3	91%	0.914	47%	0.467	S	S	*	.			trans	-105.7	0	175.3	-55.6	-59.4	0	0	0	110.8	Q453	Q453-N457 WeakPolarHBondContact O-CB 3.4Å; Q453-N457 PolarHBondContact O-N 3.08Å; Q453-N457 PolarHBondContact O-ND2 2.61Å

Retrieved 457 of 457 residues in 605.8 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).