A0A087YJZ1_POEFO Loading...

Vesicular inhibitory amino acid transporter

Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake.

AlphaFold DB , UniProt , Accession A0A087YJZ1, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 419 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	P	68.8	Low	90	Very high	116 Å²	116	46 Å²	46	75%	0.753	24%	0.243	S	C	*	.				0	140.7	0	13	-30.5	0	0	0	108.6
2	T	87.4	Confident	90.5	Very high	68 Å²	68	42.2 Å²	42.2	42%	0.417	22%	0.223	S	C	.	.			trans	-80.9	160.9	175.8	51.2	0	0	0	0	111.3	R156 I224 E226	T2-R156 PolarHBondContact O-NE 3.4Å; T2-R156 PolarHBondContact O-NH2 3.23Å; T2-I224 CarbonylContact C-O 3.58Å; T2-I224 WeakPolarHBondContact CA-O 3.45Å; T2-I224 WeakPolarHBondContact CB-O 3.27Å; T2-E226 HydrophobicContact CG2-CG 4.45Å; T2-E226 WeakPolarHBondContact OG1-CG 3.37Å; T2-E226 PolarHBondContact OG1-OE1 3.13Å
3	I	90.3	Very high	90.8	Very high	1 Å²	1	40.8 Å²	40.8	1%	0.005	22%	0.217	C	C	.	.	B	Isolated β-bridge	trans	-126	152.2	174.7	64.1	171.7	0	0	0	110.7	E7 A8 R156 L221 I224 M225 E226	I3-E7 WeakPolarHBondContact CA-OE2 3.31Å; I3-E7 HydrophobicContact CB-CB 4.05Å; I3-A8 HydrophobicContact CD1-CB 3.95Å; I3-R156 HydrophobicContact CG2-CG 4.28Å; I3-L221 HydrophobicContact CD1-CD1 3.52Å; I3-L221 HydrophobicContact CD1-CG 4.41Å; I3-I224 HydrophobicContact CD1-CD1 3.65Å; I3-I224 HydrophobicContact CD1-CG1 3.95Å; I3-I224 HydrophobicContact CG1-CD1 3.86Å; I3-I224 HydrophobicContact CG1-CG1 3.89Å; I3-I224 HydrophobicContact CG2-CD1 4.17Å; I3-I224 PolarHBondContact N-O 2.86Å; I3-M225 HydrophobicContact CG1-CG 4.48Å; I3-M225 WeakPolarHBondContact O-CA 3.37Å; I3-E226 PolarHBondContact O-N 3.37Å
4	T	93.7	Very high	90.9	Very high	50 Å²	50	38.1 Å²	38.1	31%	0.307	20%	0.203	S	C	.	.			trans	-72.3	161.5	174.5	61.8	0	0	0	0	111.4	W6 E7 A8	T4-W6 PolarHBondContact O-N 3.27Å; T4-E7 PolarHBondContact N-OE2 2.96Å; T4-E7 PolarHBondContact O-N 3.47Å; T4-E7 WeakPolarHBondContact OG1-CG 3.21Å; T4-E7 PolarHBondContact OG1-N 3.22Å; T4-E7 PolarHBondContact OG1-OE2 3.02Å; T4-A8 PolarHBondContact O-N 3.35Å
5	A	93.7	Very high	91.1	Very high	15 Å²	15	36.3 Å²	36.3	12%	0.124	20%	0.195	C	C	.	.	H	α-helix	trans	-60	-29.8	172.6	0	0	0	0	0	112.4	A8 S9 M225 Q230	A5-A8 PolarHBondContact O-N 2.74Å; A5-S9 PolarHBondContact O-N 3.08Å; A5-S9 PolarHBondContact O-OG 3.3Å; A5-M225 HydrophobicContact CB-CE 3.99Å; A5-Q230 HydrophobicContact CB-CB 3.94Å
6	W	91.5	Very high	91.2	Very high	161 Å²	161	34 Å²	34	61%	0.61	18%	0.183	S	C	*	.	H	α-helix	trans	-67.7	-46.6	176.3	-171.8	-122.2	0	0	0	112.7	T4 A8 S9 W10	T4-W6 PolarHBondContact O-N 3.27Å; W6-A8 VanDerWaalsContact C-N 3.26Å; W6-A8 PolarHBondContact O-N 3.36Å; W6-S9 VanDerWaalsContact O-CB 3.31Å; W6-S9 WeakPolarHBondContact O-CB 3.34Å; W6-S9 PolarHBondContact O-N 3.08Å; W6-W10 AromaticContact CD1-CD1 3.97Å; W6-W10 AromaticContact CD1-NE1 3.24Å; W6-W10 AromaticContact CD2-CE2 3.92Å; W6-W10 HydrophobicContact CD2-CZ2 4.08Å; W6-W10 AromaticContact CD2-NE1 3.58Å; W6-W10 AromaticContact CE2-CE2 3.46Å; W6-W10 VanDerWaalsContact CE2-CE2 3.46Å; W6-W10 AromaticContact CE2-CZ2 3.31Å; W6-W10 AromaticContact CE2-NE1 3.24Å; W6-W10 HydrophobicContact CE3-CZ2 4.43Å; W6-W10 AromaticContact CG-NE1 3.65Å; W6-W10 AromaticContact CH2-CH2 3.75Å; W6-W10 HydrophobicContact CH2-CH2 3.75Å; W6-W10 AromaticContact CH2-CZ2 3.44Å; W6-W10 HydrophobicContact CH2-CZ2 3.44Å; W6-W10 VanDerWaalsContact CH2-CZ2 3.44Å; W6-W10 AromaticContact CZ2-CE2 3.71Å; W6-W10 AromaticContact CZ2-CH2 3.79Å; W6-W10 HydrophobicContact CZ2-CH2 3.79Å; W6-W10 AromaticContact CZ2-CZ2 3.01Å; W6-W10 HydrophobicContact CZ2-CZ2 3.01Å; W6-W10 AromaticContact CZ2-NE1 3.97Å; W6-W10 HydrophobicContact CZ3-CH2 4.4Å; W6-W10 HydrophobicContact CZ3-CZ2 4.13Å; W6-W10 AromaticContact NE1-CE2 3.65Å; W6-W10 AromaticContact NE1-CZ2 3.81Å; W6-W10 AromaticContact NE1-NE1 2.96Å; W6-W10 PolarHBondContact O-N 2.81Å; W6-W10 VanDerWaalsContact O-N 3.09Å
7	E	91.9	Very high	90.9	Very high	46 Å²	46	32.4 Å²	32.4	22%	0.215	17%	0.174	C	C	.	.	H	α-helix	trans	-61.7	-37.8	173.7	-71.1	166.5	125	0	0	111.4	I3 T4 W10 N11	I3-E7 WeakPolarHBondContact CA-OE2 3.31Å; I3-E7 HydrophobicContact CB-CB 4.05Å; T4-E7 PolarHBondContact N-OE2 2.96Å; T4-E7 PolarHBondContact O-N 3.47Å; T4-E7 WeakPolarHBondContact OG1-CG 3.21Å; T4-E7 PolarHBondContact OG1-N 3.22Å; T4-E7 PolarHBondContact OG1-OE2 3.02Å; E7-W10 PolarHBondContact O-N 3.32Å; E7-N11 PolarHBondContact O-N 3.2Å; E7-N11 VanDerWaalsContact O-N 3.16Å
8	A	93.1	Very high	90.4	Very high	0 Å²	0	30.7 Å²	30.7	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-64.3	-42.5	173.7	0	0	0	0	0	112	I3 T4 A5 W6 W10 N11 V12 L221 M225 M234	I3-A8 HydrophobicContact CD1-CB 3.95Å; T4-A8 PolarHBondContact O-N 3.35Å; A5-A8 PolarHBondContact O-N 2.74Å; W6-A8 VanDerWaalsContact C-N 3.26Å; W6-A8 PolarHBondContact O-N 3.36Å; A8-W10 PolarHBondContact O-N 3.22Å; A8-N11 PolarHBondContact O-N 3.09Å; A8-V12 PolarHBondContact O-N 3.24Å; A8-L221 HydrophobicContact CB-CD1 4.16Å; A8-L221 HydrophobicContact CB-CD2 3.99Å; A8-L221 HydrophobicContact CB-CG 3.99Å; A8-M225 HydrophobicContact CB-CE 4.47Å; A8-M225 HydrophobicContact CB-CG 3.94Å; A8-M225 HydrophobicContact CB-SD 3.87Å; A8-M234 HydrophobicContact CB-CE 3.8Å
9	S	93.6	Very high	90.2	Very high	16 Å²	16	29.1 Å²	29.1	11%	0.112	16%	0.156	C	C	.	.	H	α-helix	trans	-55	-41	173.4	-59.3	0	0	0	0	111.8	A5 W6 V12 T13 M234 T238	A5-S9 PolarHBondContact O-N 3.08Å; A5-S9 PolarHBondContact O-OG 3.3Å; W6-S9 VanDerWaalsContact O-CB 3.31Å; W6-S9 WeakPolarHBondContact O-CB 3.34Å; W6-S9 PolarHBondContact O-N 3.08Å; S9-V12 PolarHBondContact O-N 3.35Å; S9-T13 VanDerWaalsContact O-CB 3.25Å; S9-T13 WeakPolarHBondContact O-CB 3.14Å; S9-T13 PolarHBondContact O-N 2.7Å; S9-T13 PolarHBondContact O-OG1 3.3Å; S9-M234 WeakPolarHBondContact OG-CG 3.44Å; S9-T238 WeakPolarHBondContact O-CG2 3.23Å
10	W	92.3	Very high	89.9	Confident	30 Å²	30	27.8 Å²	27.8	11%	0.114	15%	0.149	C	C	.	.	H	α-helix	trans	-69.7	-36.8	179.4	-62	134.6	0	0	0	113.6	W6 E7 A8 T13 N14 L163	W6-W10 AromaticContact CD1-CD1 3.97Å; W6-W10 AromaticContact CD1-NE1 3.24Å; W6-W10 AromaticContact CD2-CE2 3.92Å; W6-W10 HydrophobicContact CD2-CZ2 4.08Å; W6-W10 AromaticContact CD2-NE1 3.58Å; W6-W10 AromaticContact CE2-CE2 3.46Å; W6-W10 VanDerWaalsContact CE2-CE2 3.46Å; W6-W10 AromaticContact CE2-CZ2 3.31Å; W6-W10 AromaticContact CE2-NE1 3.24Å; W6-W10 HydrophobicContact CE3-CZ2 4.43Å; W6-W10 AromaticContact CG-NE1 3.65Å; W6-W10 AromaticContact CH2-CH2 3.75Å; W6-W10 HydrophobicContact CH2-CH2 3.75Å; W6-W10 AromaticContact CH2-CZ2 3.44Å; W6-W10 HydrophobicContact CH2-CZ2 3.44Å; W6-W10 VanDerWaalsContact CH2-CZ2 3.44Å; W6-W10 AromaticContact CZ2-CE2 3.71Å; W6-W10 AromaticContact CZ2-CH2 3.79Å; W6-W10 HydrophobicContact CZ2-CH2 3.79Å; W6-W10 AromaticContact CZ2-CZ2 3.01Å; W6-W10 HydrophobicContact CZ2-CZ2 3.01Å; W6-W10 AromaticContact CZ2-NE1 3.97Å; W6-W10 HydrophobicContact CZ3-CH2 4.4Å; W6-W10 HydrophobicContact CZ3-CZ2 4.13Å; W6-W10 AromaticContact NE1-CE2 3.65Å; W6-W10 AromaticContact NE1-CZ2 3.81Å; W6-W10 AromaticContact NE1-NE1 2.96Å; W6-W10 PolarHBondContact O-N 2.81Å; W6-W10 VanDerWaalsContact O-N 3.09Å; E7-W10 PolarHBondContact O-N 3.32Å; A8-W10 PolarHBondContact O-N 3.22Å; W10-T13 PolarHBondContact O-N 3.45Å; W10-N14 WeakPolarHBondContact O-CB 3.19Å; W10-N14 PolarHBondContact O-N 2.93Å; W10-L163 HydrophobicContact CB-CB 4.45Å; W10-L163 HydrophobicContact CD2-CD1 4.06Å; W10-L163 VanDerWaalsContact CE2-CD1 3.45Å; W10-L163 HydrophobicContact CG-CB 4.08Å; W10-L163 HydrophobicContact CG-CD1 4.27Å; W10-L163 HydrophobicContact CZ2-CD1 3.66Å
11	N	93.8	Very high	89.8	Confident	3 Å²	3	26.6 Å²	26.6	2%	0.016	14%	0.143	C	C	.	.	H	α-helix	trans	-64.9	-44.9	173.6	-70.1	-20.6	0	0	0	111.3	E7 A8 N14 A15 S159 S162 L221 L291	E7-N11 PolarHBondContact O-N 3.2Å; E7-N11 VanDerWaalsContact O-N 3.16Å; A8-N11 PolarHBondContact O-N 3.09Å; N11-N14 PolarHBondContact O-N 3.5Å; N11-A15 WeakPolarHBondContact O-CB 3.49Å; N11-A15 PolarHBondContact O-N 3.49Å; N11-S159 PolarHBondContact ND2-OG 2.95Å; N11-S159 VanDerWaalsContact OD1-CA 3.27Å; N11-S159 WeakPolarHBondContact OD1-CA 3.25Å; N11-S159 PolarHBondContact OD1-OG 3.43Å; N11-S162 PolarHBondContact OD1-OG 3.5Å; N11-L221 HydrophobicContact CB-CD1 3.97Å; N11-L221 HydrophobicContact CB-CD2 4.45Å; N11-L291 HydrophobicContact CB-CD1 4.38Å; N11-L291 WeakPolarHBondContact O-CD2 3.11Å
12	V	95.5	Very high	90.7	Very high	0 Å²	0	21.2 Å²	21.2	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-64.3	-44	176.2	176.6	0	0	0	0	111	A8 S9 N14 A15 I16 L218 L221 M234 L235 T238	A8-V12 PolarHBondContact O-N 3.24Å; S9-V12 PolarHBondContact O-N 3.35Å; V12-N14 VanDerWaalsContact C-N 3.33Å; V12-N14 PolarHBondContact O-N 2.98Å; V12-A15 WeakPolarHBondContact O-CB 3.32Å; V12-A15 PolarHBondContact O-N 2.93Å; V12-I16 HydrophobicContact CG1-CD1 4.37Å; V12-I16 WeakPolarHBondContact O-CG1 3.48Å; V12-I16 PolarHBondContact O-N 2.66Å; V12-L218 HydrophobicContact CG2-CD2 4.04Å; V12-L221 HydrophobicContact CG2-CD2 3.48Å; V12-L221 VanDerWaalsContact CG2-CD2 3.48Å; V12-M234 HydrophobicContact CB-SD 4.3Å; V12-M234 HydrophobicContact CG2-CE 4.23Å; V12-M234 HydrophobicContact CG2-SD 3.83Å; V12-L235 HydrophobicContact CG1-CD1 4.11Å; V12-T238 HydrophobicContact CB-CG2 4.19Å; V12-T238 HydrophobicContact CG1-CG2 4.23Å; V12-T238 WeakPolarHBondContact CG1-OG1 3.29Å
13	T	94.2	Very high	90.8	Very high	24 Å²	24	18.1 Å²	18.1	15%	0.147	9%	0.089	C	C	.	.	H	α-helix	trans	-60.8	-43.5	176.9	-58.4	0	0	0	0	110.8	S9 W10 A15 I16 Q17	S9-T13 VanDerWaalsContact O-CB 3.25Å; S9-T13 WeakPolarHBondContact O-CB 3.14Å; S9-T13 PolarHBondContact O-N 2.7Å; S9-T13 PolarHBondContact O-OG1 3.3Å; W10-T13 PolarHBondContact O-N 3.45Å; T13-A15 VanDerWaalsContact C-N 3.35Å; T13-A15 PolarHBondContact O-N 2.71Å; T13-I16 PolarHBondContact O-N 2.95Å; T13-Q17 HydrophobicContact CG2-CB 4.23Å; T13-Q17 WeakPolarHBondContact O-CA 3.47Å; T13-Q17 WeakPolarHBondContact O-CB 3.17Å; T13-Q17 PolarHBondContact O-N 3.42Å
14	N	93.1	Very high	91	Very high	3 Å²	3	18.1 Å²	18.1	2%	0.016	9%	0.089	C	C	.	.	H	α-helix	trans	-63.8	-40.6	177.3	-173.7	39	0	0	0	111.7	W10 N11 V12 G18 S162 C165 S288 L291	W10-N14 WeakPolarHBondContact O-CB 3.19Å; W10-N14 PolarHBondContact O-N 2.93Å; N11-N14 PolarHBondContact O-N 3.5Å; V12-N14 VanDerWaalsContact C-N 3.33Å; V12-N14 PolarHBondContact O-N 2.98Å; N14-G18 WeakPolarHBondContact O-CA 3.41Å; N14-G18 PolarHBondContact O-N 3.25Å; N14-S162 PolarHBondContact ND2-OG 2.99Å; N14-C165 PolarHBondContact OD1-SG 2.97Å; N14-S288 PolarHBondContact ND2-O 3.26Å; N14-S288 VanDerWaalsContact OD1-CB 3.28Å; N14-S288 WeakPolarHBondContact OD1-CB 3.46Å; N14-S288 PolarHBondContact OD1-OG 3.46Å; N14-L291 HydrophobicContact CB-CD2 4.06Å
15	A	92.9	Very high	91	Very high	11 Å²	11	15.7 Å²	15.7	9%	0.091	7%	0.074	C	C	.	.	H	α-helix	trans	-61.6	-50.6	175.8	0	0	0	0	0	112.6	N11 V12 T13 F217 L291	N11-A15 WeakPolarHBondContact O-CB 3.49Å; N11-A15 PolarHBondContact O-N 3.49Å; V12-A15 WeakPolarHBondContact O-CB 3.32Å; V12-A15 PolarHBondContact O-N 2.93Å; T13-A15 VanDerWaalsContact C-N 3.35Å; T13-A15 PolarHBondContact O-N 2.71Å; A15-F217 HydrophobicContact CB-CD2 3.69Å; A15-F217 HydrophobicContact CB-CE2 3.66Å; A15-L291 HydrophobicContact CB-CD2 4.07Å
16	I	93.2	Very high	91	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-82.5	-31	-175.8	68.7	-170.1	0	0	0	113.3	V12 T13 S211 T238 A242 K246	V12-I16 HydrophobicContact CG1-CD1 4.37Å; V12-I16 WeakPolarHBondContact O-CG1 3.48Å; V12-I16 PolarHBondContact O-N 2.66Å; T13-I16 PolarHBondContact O-N 2.95Å; I16-S211 CarbonylContact C-O 3.45Å; I16-S211 WeakPolarHBondContact CA-O 3.16Å; I16-T238 WeakPolarHBondContact CD1-O 3.41Å; I16-A242 HydrophobicContact CD1-CB 3.46Å; I16-A242 VanDerWaalsContact CD1-CB 3.46Å; I16-A242 HydrophobicContact CG1-CB 3.9Å; I16-K246 WeakPolarHBondContact O-CE 3.48Å; I16-K246 PolarHBondContact O-NZ 2.86Å
17	Q	87.1	Confident	91.2	Very high	7 Å²	7	8.8 Å²	8.8	3%	0.033	5%	0.046	C	C	.	.	H	α-helix	trans	-89.8	-38.9	-173	-158.8	61	29.2	0	0	110.9	T13 H169	T13-Q17 HydrophobicContact CG2-CB 4.23Å; T13-Q17 WeakPolarHBondContact O-CA 3.47Å; T13-Q17 WeakPolarHBondContact O-CB 3.17Å; T13-Q17 PolarHBondContact O-N 3.42Å; Q17-H169 VanDerWaalsContact CD-NE2 3.29Å; Q17-H169 WeakPolarHBondContact CG-CD2 3.25Å; Q17-H169 WeakPolarHBondContact CG-NE2 3.06Å; Q17-H169 PolarHBondContact NE2-CE1 3.21Å; Q17-H169 PolarHBondContact NE2-NE2 3.15Å
18	G	81.7	Confident	91.3	Very high	1 Å²	1	6.7 Å²	6.7	1%	0.01	4%	0.036	C	C	.	.	T	Hydrogen-bonded Turn	trans	35.9	-164	166.1	0	0	0	0	0	116.8	N14 Y116 K284	N14-G18 WeakPolarHBondContact O-CA 3.41Å; N14-G18 PolarHBondContact O-N 3.25Å; G18-Y116 WeakPolarHBondContact CA-OH 3.33Å; G18-K284 WeakPolarHBondContact O-CE 3.36Å; G18-K284 PolarHBondContact O-NZ 3.09Å
19	I	85.3	Confident	91.3	Very high	0 Å²	0	8.2 Å²	8.2	0%	0	5%	0.045	C	C	.	.	T	Hydrogen-bonded Turn	trans	-77.6	-11.6	166.2	-161.6	60.3	0	0	0	111.9	V21 L22 Y116 V119 L123 L281 K284 A285	I19-V21 VanDerWaalsContact C-N 3.27Å; I19-V21 PolarHBondContact O-N 3.35Å; I19-L22 HydrophobicContact CD1-CD1 3.52Å; I19-L22 HydrophobicContact CD1-CG 4.24Å; I19-L22 HydrophobicContact CG1-CD1 3.82Å; I19-L22 WeakPolarHBondContact O-CB 3.36Å; I19-L22 WeakPolarHBondContact O-CG 3.47Å; I19-L22 PolarHBondContact O-N 2.96Å; I19-Y116 HydrophobicContact CB-CD1 4.01Å; I19-Y116 HydrophobicContact CB-CE1 3.6Å; I19-Y116 HydrophobicContact CG2-CD1 3.55Å; I19-Y116 HydrophobicContact CG2-CE1 3.39Å; I19-Y116 HydrophobicContact CG2-CG 4.39Å; I19-Y116 PolarHBondContact N-OH 2.76Å; I19-V119 HydrophobicContact CD1-CG1 4.37Å; I19-V119 HydrophobicContact CG1-CB 4.36Å; I19-V119 HydrophobicContact CG1-CG1 3.62Å; I19-L123 HydrophobicContact CD1-CD1 4.46Å; I19-L281 HydrophobicContact CD1-CB 4.29Å; I19-L281 HydrophobicContact CD1-CD2 4.04Å; I19-K284 HydrophobicContact CD1-CD 4.43Å; I19-A285 HydrophobicContact CB-CB 4.36Å; I19-A285 HydrophobicContact CD1-CB 4.05Å; I19-A285 HydrophobicContact CG1-CB 4.08Å
20	F	84.6	Confident	91.3	Very high	4 Å²	4	9 Å²	9	2%	0.018	5%	0.047	C	C	.	.	G	3₁₀ helix	trans	-71.4	-16.9	-167.7	-46.9	-47.4	0	0	0	114.9	L22 G23 T112 L115 Y116 F210 F347 M351	F20-L22 PolarHBondContact O-N 3.45Å; F20-L22 VanDerWaalsContact O-N 3.1Å; F20-G23 PolarHBondContact O-N 2.95Å; F20-G23 VanDerWaalsContact O-N 3.14Å; F20-T112 HydrophobicContact CE2-CG2 3.91Å; F20-T112 HydrophobicContact CZ-CG2 3.6Å; F20-L115 HydrophobicContact CD1-CD1 4.46Å; F20-L115 HydrophobicContact CE1-CB 3.75Å; F20-L115 HydrophobicContact CE1-CD1 3.94Å; F20-L115 HydrophobicContact CE1-CG 4.44Å; F20-L115 HydrophobicContact CZ-CB 4.48Å; F20-Y116 HydrophobicContact CE1-CE2 4.43Å; F20-Y116 HydrophobicContact CE2-CE2 4.13Å; F20-Y116 HydrophobicContact CZ-CD2 4.15Å; F20-Y116 HydrophobicContact CZ-CE1 4.46Å; F20-Y116 AromaticContact CZ-CE2 3.56Å; F20-Y116 HydrophobicContact CZ-CE2 3.56Å; F20-Y116 AromaticContact CZ-CZ 3.7Å; F20-F210 HydrophobicContact CD1-CD1 4.49Å; F20-F210 AromaticContact CD1-CE1 3.81Å; F20-F210 HydrophobicContact CD1-CE1 3.81Å; F20-F210 HydrophobicContact CD2-CD1 4.23Å; F20-F210 AromaticContact CD2-CE1 3.66Å; F20-F210 HydrophobicContact CD2-CE1 3.66Å; F20-F210 HydrophobicContact CD2-CZ 4.44Å; F20-F210 AromaticContact CE1-CE1 3.8Å; F20-F210 HydrophobicContact CE1-CE1 3.8Å; F20-F210 HydrophobicContact CE1-CZ 4.45Å; F20-F210 AromaticContact CE2-CE1 3.64Å; F20-F210 HydrophobicContact CE2-CE1 3.64Å; F20-F210 HydrophobicContact CE2-CZ 4.02Å; F20-F210 HydrophobicContact CG-CD1 4.18Å; F20-F210 AromaticContact CG-CE1 3.75Å; F20-F210 HydrophobicContact CG-CE1 3.75Å; F20-F210 AromaticContact CZ-CE1 3.72Å; F20-F210 HydrophobicContact CZ-CE1 3.72Å; F20-F210 HydrophobicContact CZ-CZ 4.04Å; F20-F347 HydrophobicContact CD1-CE2 4.41Å; F20-F347 HydrophobicContact CD1-CZ 4.27Å; F20-M351 HydrophobicContact CB-CE 3.66Å; F20-M351 HydrophobicContact CB-SD 4.09Å; F20-M351 HydrophobicContact CD1-CE 3.67Å; F20-M351 HydrophobicContact CG-CE 4.04Å
21	V	88.3	Confident	91.3	Very high	2 Å²	2	7.6 Å²	7.6	1%	0.012	4%	0.042	C	C	.	.	G	3₁₀ helix	trans	-54	-26.7	169.7	69.2	0	0	0	0	113	I19 G23 L24 P25 K246 F249	I19-V21 VanDerWaalsContact C-N 3.27Å; I19-V21 PolarHBondContact O-N 3.35Å; V21-G23 VanDerWaalsContact C-N 3.28Å; V21-G23 PolarHBondContact O-N 3.5Å; V21-L24 HydrophobicContact CG2-CD1 4.38Å; V21-L24 PolarHBondContact O-N 2.66Å; V21-P25 WeakPolarHBondContact O-CD 3.5Å; V21-K246 HydrophobicContact CG2-CG 4.29Å; V21-F249 HydrophobicContact CG2-CD1 3.77Å; V21-F249 HydrophobicContact CG2-CE1 4.09Å; V21-F249 HydrophobicContact CG2-CG 4.17Å
22	L	87	Confident	91.3	Very high	4 Å²	4	7.4 Å²	7.4	2%	0.021	4%	0.041	C	C	.	.	G	3₁₀ helix	trans	-68.1	-24.5	-179	-60.6	-178.3	0	0	0	113.8	I19 F20 F249 V264 I265 L281	I19-L22 HydrophobicContact CD1-CD1 3.52Å; I19-L22 HydrophobicContact CD1-CG 4.24Å; I19-L22 HydrophobicContact CG1-CD1 3.82Å; I19-L22 WeakPolarHBondContact O-CB 3.36Å; I19-L22 WeakPolarHBondContact O-CG 3.47Å; I19-L22 PolarHBondContact O-N 2.96Å; F20-L22 PolarHBondContact O-N 3.45Å; F20-L22 VanDerWaalsContact O-N 3.1Å; L22-F249 HydrophobicContact CD2-CZ 4.47Å; L22-V264 HydrophobicContact CB-CG1 4.25Å; L22-V264 HydrophobicContact CD1-CG1 3.93Å; L22-I265 HydrophobicContact CB-CG2 4.17Å; L22-I265 HydrophobicContact CD2-CG2 3.62Å; L22-I265 HydrophobicContact CG-CG2 4.49Å; L22-I265 PolarHBondContact O-N 3.28Å; L22-L281 HydrophobicContact CD1-CD1 3.99Å; L22-L281 HydrophobicContact CD1-CD2 4.2Å; L22-L281 HydrophobicContact CD2-CD1 3.77Å; L22-L281 HydrophobicContact CD2-CD2 3.91Å; L22-L281 HydrophobicContact CG-CD2 4.44Å
23	G	89.9	Confident	91.2	Very high	2 Å²	2	11.2 Å²	11.2	2%	0.021	6%	0.056	C	C	.	.	G	3₁₀ helix	trans	-94.5	-8.9	179.4	0	0	0	0	0	114.4	F20 V21 F26 A27 E263	F20-G23 PolarHBondContact O-N 2.95Å; F20-G23 VanDerWaalsContact O-N 3.14Å; V21-G23 VanDerWaalsContact C-N 3.28Å; V21-G23 PolarHBondContact O-N 3.5Å; G23-F26 PolarHBondContact O-N 3.01Å; G23-A27 PolarHBondContact O-N 2.94Å; G23-E263 WeakPolarHBondContact CA-O 3.46Å
24	L	94.8	Very high	91.1	Very high	1 Å²	1	13.2 Å²	13.2	1%	0.005	7%	0.068	C	C	.	.	H	α-helix	trans	-66.9	-39.4	-179.3	-67.1	177.3	0	0	0	114.1	V21 F26 A27 L28 L39 V207 I208 K246 S250	V21-L24 HydrophobicContact CG2-CD1 4.38Å; V21-L24 PolarHBondContact O-N 2.66Å; L24-F26 VanDerWaalsContact C-N 3.32Å; L24-F26 PolarHBondContact O-N 3.48Å; L24-A27 PolarHBondContact O-N 3.48Å; L24-L28 PolarHBondContact O-N 3.47Å; L24-L39 HydrophobicContact CD1-CD1 4.15Å; L24-L39 HydrophobicContact CD2-CD1 4.05Å; L24-V207 HydrophobicContact CD2-CG1 4.21Å; L24-I208 HydrophobicContact CD2-CG1 4.27Å; L24-K246 HydrophobicContact CD1-CB 3.79Å; L24-K246 HydrophobicContact CD1-CD 3.64Å; L24-K246 HydrophobicContact CD1-CG 3.62Å; L24-S250 WeakPolarHBondContact CB-OG 3.39Å
25	P	94.4	Very high	91.2	Very high	0 Å²	0	13 Å²	13	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-57.2	-46	173.5	-23.5	31.9	0	0	0	112.1	V21 A27 L28 V29 F249 A253 V254 T261 I265	V21-P25 WeakPolarHBondContact O-CD 3.5Å; P25-A27 PolarHBondContact O-N 3.18Å; P25-L28 WeakPolarHBondContact O-CB 3.22Å; P25-L28 PolarHBondContact O-N 2.95Å; P25-L28 VanDerWaalsContact O-N 3.11Å; P25-V29 PolarHBondContact O-N 2.91Å; P25-F249 HydrophobicContact CG-CD1 4.09Å; P25-F249 HydrophobicContact CG-CE1 3.79Å; P25-A253 HydrophobicContact CB-CB 3.7Å; P25-A253 HydrophobicContact CG-CB 3.71Å; P25-V254 HydrophobicContact CB-CG2 4.42Å; P25-V254 WeakPolarHBondContact O-CG2 3.27Å; P25-T261 HydrophobicContact CB-CG2 3.82Å; P25-I265 HydrophobicContact CB-CD1 3.99Å; P25-I265 HydrophobicContact CB-CG1 4.47Å; P25-I265 HydrophobicContact CG-CB 4.19Å; P25-I265 HydrophobicContact CG-CD1 4.14Å; P25-I265 HydrophobicContact CG-CG1 4.07Å
26	F	93.6	Very high	91.3	Very high	30 Å²	30	14.1 Å²	14.1	13%	0.132	7%	0.071	C	C	.	.	H	α-helix	trans	-60.1	-46.3	177.2	179	-100.3	0	0	0	111.8	G23 L24 L28 V29 Q30 T261 E263	G23-F26 PolarHBondContact O-N 3.01Å; L24-F26 VanDerWaalsContact C-N 3.32Å; L24-F26 PolarHBondContact O-N 3.48Å; F26-L28 VanDerWaalsContact C-N 3.27Å; F26-L28 PolarHBondContact O-N 3.27Å; F26-V29 PolarHBondContact O-N 3.39Å; F26-Q30 HydrophobicContact CD1-CG 4.5Å; F26-Q30 HydrophobicContact CE1-CG 4.1Å; F26-Q30 HydrophobicContact CZ-CG 4.14Å; F26-Q30 PolarHBondContact O-N 3.43Å; F26-T261 HydrophobicContact CB-CG2 4.24Å; F26-T261 WeakPolarHBondContact CD2-O 3.46Å; F26-E263 HydrophobicContact CD1-CG 4.18Å; F26-E263 HydrophobicContact CD2-CG 4.29Å; F26-E263 HydrophobicContact CE1-CG 3.93Å; F26-E263 HydrophobicContact CE2-CG 4.06Å; F26-E263 HydrophobicContact CG-CG 4.34Å; F26-E263 HydrophobicContact CZ-CG 3.87Å
27	A	94.7	Very high	91.4	Very high	1 Å²	1	20.8 Å²	20.8	1%	0.008	10%	0.104	C	C	.	.	H	α-helix	trans	-59.2	-38.3	174.8	0	0	0	0	0	111.9	G23 L24 P25 Q30 S31 S204 V207	G23-A27 PolarHBondContact O-N 2.94Å; L24-A27 PolarHBondContact O-N 3.48Å; P25-A27 PolarHBondContact O-N 3.18Å; A27-Q30 CarbonylContact O-C 3.41Å; A27-Q30 PolarHBondContact O-N 3.46Å; A27-S31 WeakPolarHBondContact O-CB 3.48Å; A27-S31 PolarHBondContact O-N 2.9Å; A27-S31 PolarHBondContact O-OG 2.88Å; A27-S204 WeakPolarHBondContact O-CB 3.31Å; A27-S204 PolarHBondContact O-OG 3.19Å; A27-V207 HydrophobicContact CB-CB 4.04Å; A27-V207 HydrophobicContact CB-CG1 3.57Å
28	L	95	Very high	91.9	Very high	1 Å²	1	21.8 Å²	21.8	1%	0.005	11%	0.111	C	C	.	.	H	α-helix	trans	-68	-37.8	176	-74.4	-168.5	0	0	0	113.1	L24 P25 F26 Q30 S31 G32 G35 L36 L39 V254	L24-L28 PolarHBondContact O-N 3.47Å; P25-L28 WeakPolarHBondContact O-CB 3.22Å; P25-L28 PolarHBondContact O-N 2.95Å; P25-L28 VanDerWaalsContact O-N 3.11Å; F26-L28 VanDerWaalsContact C-N 3.27Å; F26-L28 PolarHBondContact O-N 3.27Å; L28-Q30 PolarHBondContact O-N 3.32Å; L28-S31 PolarHBondContact O-N 2.98Å; L28-G32 WeakPolarHBondContact O-CA 3.26Å; L28-G32 PolarHBondContact O-N 3.49Å; L28-G35 VanDerWaalsContact CD2-C 3.42Å; L28-L36 HydrophobicContact CD1-CD1 4.03Å; L28-L36 HydrophobicContact CD2-CB 4.31Å; L28-L39 HydrophobicContact CD1-CD2 4.43Å; L28-V254 HydrophobicContact CB-CG2 3.8Å
29	V	93.1	Very high	92.6	Very high	32 Å²	32	21.7 Å²	21.7	19%	0.194	11%	0.11	C	C	.	.	H	α-helix	trans	-58.9	-42.8	171.4	176.4	0	0	0	0	110.3	P25 F26 S31 V254 G258 T261	P25-V29 PolarHBondContact O-N 2.91Å; F26-V29 PolarHBondContact O-N 3.39Å; V29-S31 VanDerWaalsContact C-N 3.32Å; V29-S31 PolarHBondContact O-N 2.86Å; V29-V254 HydrophobicContact CG2-CG1 4.19Å; V29-V254 HydrophobicContact CG2-CG2 3.82Å; V29-G258 WeakPolarHBondContact CG2-O 3.32Å; V29-T261 HydrophobicContact CG2-CG2 4.34Å
30	Q	92.2	Very high	93.2	Very high	33 Å²	33	24.8 Å²	24.8	15%	0.154	13%	0.129	C	C	.	.	T	Hydrogen-bonded Turn	trans	-76.7	-9.2	179.7	-74.1	-162.7	-27.7	0	0	115.1	F26 A27 L28 V196 D200 S204	F26-Q30 HydrophobicContact CD1-CG 4.5Å; F26-Q30 HydrophobicContact CE1-CG 4.1Å; F26-Q30 HydrophobicContact CZ-CG 4.14Å; F26-Q30 PolarHBondContact O-N 3.43Å; A27-Q30 CarbonylContact O-C 3.41Å; A27-Q30 PolarHBondContact O-N 3.46Å; L28-Q30 PolarHBondContact O-N 3.32Å; Q30-V196 WeakPolarHBondContact O-CG1 3.46Å; Q30-D200 HydrophobicContact CB-CB 4.19Å; Q30-D200 HydrophobicContact CG-CB 4.38Å; Q30-D200 PolarHBondContact NE2-OD1 3.38Å; Q30-S204 WeakPolarHBondContact CB-OG 3.17Å; Q30-S204 PolarHBondContact OE1-OG 3.34Å
31	S	93.9	Very high	93.8	Very high	0 Å²	0	28.6 Å²	28.6	0%	0	15%	0.149	C	C	.	.	T	Hydrogen-bonded Turn	trans	-128.3	-5.1	-176.9	55.8	0	0	0	0	114.5	A27 L28 V29 G35	A27-S31 WeakPolarHBondContact O-CB 3.48Å; A27-S31 PolarHBondContact O-N 2.9Å; A27-S31 PolarHBondContact O-OG 2.88Å; L28-S31 PolarHBondContact O-N 2.98Å; V29-S31 VanDerWaalsContact C-N 3.32Å; V29-S31 PolarHBondContact O-N 2.86Å; S31-G35 PolarHBondContact O-N 2.65Å; S31-G35 WeakPolarHBondContact OG-CA 3.41Å
32	G	92.6	Very high	94.2	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	58.5	-149.3	175.2	0	0	0	0	0	113.6	L28 V34 G35 L36 S193	L28-G32 WeakPolarHBondContact O-CA 3.26Å; L28-G32 PolarHBondContact O-N 3.49Å; G32-V34 VanDerWaalsContact C-N 3.25Å; G32-V34 PolarHBondContact O-N 2.67Å; G32-G35 PolarHBondContact O-N 2.83Å; G32-L36 PolarHBondContact O-N 3.2Å; G32-S193 VanDerWaalsContact CA-O 3.3Å; G32-S193 WeakPolarHBondContact CA-O 3.2Å
33	Y	92.8	Very high	94.7	Very high	79 Å²	79	29.2 Å²	29.2	31%	0.31	15%	0.154	S	C	.	.	H	α-helix	trans	-63.3	-30.3	178.9	-75.1	-72.3	0	0	0	113.4	G35 L36 M37 W189 L192 S193 L194	Y33-G35 VanDerWaalsContact C-N 3.33Å; Y33-L36 WeakPolarHBondContact O-CB 3.37Å; Y33-L36 PolarHBondContact O-N 2.94Å; Y33-M37 PolarHBondContact O-N 3.49Å; Y33-W189 PolarHBondContact OH-O 2.93Å; Y33-L192 HydrophobicContact CD1-CB 4.3Å; Y33-L192 HydrophobicContact CD1-CD1 4.1Å; Y33-L192 HydrophobicContact CD2-CB 3.82Å; Y33-L192 HydrophobicContact CE1-CB 3.96Å; Y33-L192 HydrophobicContact CE1-CD1 3.61Å; Y33-L192 HydrophobicContact CE1-CG 4.42Å; Y33-L192 HydrophobicContact CE2-CB 3.44Å; Y33-L192 VanDerWaalsContact CE2-CB 3.44Å; Y33-L192 WeakPolarHBondContact CE2-O 3.23Å; Y33-L192 HydrophobicContact CG-CB 4.23Å; Y33-L192 VanDerWaalsContact CZ-CB 3.49Å; Y33-S193 PolarHBondContact N-O 3.33Å; Y33-L194 HydrophobicContact CD2-CG 4.33Å
34	V	93.9	Very high	95	Very high	66 Å²	66	35.2 Å²	35.2	40%	0.4	18%	0.176	S	C	.	.	H	α-helix	trans	-66	-41.4	176.6	-177.1	0	0	0	0	109.7	G32 L36 M37 V38 F201	G32-V34 VanDerWaalsContact C-N 3.25Å; G32-V34 PolarHBondContact O-N 2.67Å; V34-L36 VanDerWaalsContact C-N 3.3Å; V34-L36 PolarHBondContact O-N 3.4Å; V34-M37 WeakPolarHBondContact O-CB 3.29Å; V34-M37 PolarHBondContact O-N 3.3Å; V34-V38 HydrophobicContact CG1-CG2 4.43Å; V34-V38 WeakPolarHBondContact O-CG2 3.48Å; V34-V38 PolarHBondContact O-N 3.16Å; V34-F201 HydrophobicContact CB-CE2 3.92Å; V34-F201 HydrophobicContact CG1-CE2 3.48Å; V34-F201 VanDerWaalsContact CG1-CE2 3.48Å; V34-F201 HydrophobicContact CG1-CZ 3.63Å
35	G	94.8	Very high	95.2	Very high	0 Å²	0	35.5 Å²	35.5	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-54	-43.4	171.5	0	0	0	0	0	114.1	L28 S31 G32 Y33 M37 V38 L39	L28-G35 VanDerWaalsContact CD2-C 3.42Å; S31-G35 PolarHBondContact O-N 2.65Å; S31-G35 WeakPolarHBondContact OG-CA 3.41Å; G32-G35 PolarHBondContact O-N 2.83Å; Y33-G35 VanDerWaalsContact C-N 3.33Å; G35-M37 PolarHBondContact O-N 3.47Å; G35-V38 PolarHBondContact O-N 2.83Å; G35-L39 WeakPolarHBondContact O-CB 3.46Å; G35-L39 PolarHBondContact O-N 3.01Å
36	L	95.1	Very high	95.3	Very high	34 Å²	34	35.6 Å²	35.6	18%	0.178	18%	0.178	C	C	.	.	H	α-helix	trans	-63.3	-42	177.8	-173	66.8	0	0	0	111.7	L28 G32 Y33 V34 L39 V40 T247 L251	L28-L36 HydrophobicContact CD1-CD1 4.03Å; L28-L36 HydrophobicContact CD2-CB 4.31Å; G32-L36 PolarHBondContact O-N 3.2Å; Y33-L36 WeakPolarHBondContact O-CB 3.37Å; Y33-L36 PolarHBondContact O-N 2.94Å; V34-L36 VanDerWaalsContact C-N 3.3Å; V34-L36 PolarHBondContact O-N 3.4Å; L36-L39 PolarHBondContact O-N 2.67Å; L36-V40 PolarHBondContact O-N 2.78Å; L36-T247 HydrophobicContact CD1-CG2 3.79Å; L36-L251 HydrophobicContact CD2-CD1 4.42Å
37	M	95.7	Very high	95.5	Very high	140 Å²	140	35.1 Å²	35.1	69%	0.69	18%	0.177	S	C	*	.	H	α-helix	trans	-63.2	-43.7	172.8	-76.3	-122.2	81.3	0	0	111.8	Y33 V34 G35 L39 V40 L41	Y33-M37 PolarHBondContact O-N 3.49Å; V34-M37 WeakPolarHBondContact O-CB 3.29Å; V34-M37 PolarHBondContact O-N 3.3Å; G35-M37 PolarHBondContact O-N 3.47Å; M37-L39 VanDerWaalsContact C-N 3.33Å; M37-L39 PolarHBondContact O-N 3.27Å; M37-V40 PolarHBondContact O-N 3.37Å; M37-L41 VanDerWaalsContact O-CB 3.26Å; M37-L41 WeakPolarHBondContact O-CB 3.34Å; M37-L41 PolarHBondContact O-N 3.49Å
38	V	96.3	Very high	95.7	Very high	27 Å²	27	36.5 Å²	36.5	16%	0.164	18%	0.183	C	C	.	.	H	α-helix	trans	-62.1	-41.2	177.4	174.8	0	0	0	0	110.6	V34 G35 V40 L41 S42 V205 I208	V34-V38 HydrophobicContact CG1-CG2 4.43Å; V34-V38 WeakPolarHBondContact O-CG2 3.48Å; V34-V38 PolarHBondContact O-N 3.16Å; G35-V38 PolarHBondContact O-N 2.83Å; V38-V40 PolarHBondContact O-N 2.9Å; V38-L41 PolarHBondContact O-N 3.3Å; V38-S42 VanDerWaalsContact O-CB 3.28Å; V38-S42 WeakPolarHBondContact O-CB 3.39Å; V38-S42 PolarHBondContact O-N 3.38Å; V38-S42 PolarHBondContact O-OG 2.85Å; V38-V205 HydrophobicContact CG1-CG1 4.43Å; V38-V205 HydrophobicContact CG1-CG2 4.35Å; V38-I208 HydrophobicContact CB-CD1 4.35Å; V38-I208 HydrophobicContact CG1-CD1 4.19Å; V38-I208 HydrophobicContact CG1-CG2 4.06Å
39	L	96.9	Very high	95.8	Very high	0 Å²	0	36.5 Å²	36.5	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-56.3	-49	177.2	-176.5	70.7	0	0	0	112.1	L24 L28 G35 L36 M37 A43 I208 Y212	L24-L39 HydrophobicContact CD1-CD1 4.15Å; L24-L39 HydrophobicContact CD2-CD1 4.05Å; L28-L39 HydrophobicContact CD1-CD2 4.43Å; G35-L39 WeakPolarHBondContact O-CB 3.46Å; G35-L39 PolarHBondContact O-N 3.01Å; L36-L39 PolarHBondContact O-N 2.67Å; M37-L39 VanDerWaalsContact C-N 3.33Å; M37-L39 PolarHBondContact O-N 3.27Å; L39-A43 PolarHBondContact O-N 3.05Å; L39-I208 HydrophobicContact CB-CD1 4.47Å; L39-I208 HydrophobicContact CB-CG2 4.39Å; L39-I208 HydrophobicContact CD1-CG1 4.3Å; L39-I208 HydrophobicContact CD1-CG2 4.05Å; L39-Y212 HydrophobicContact CD1-CE2 3.87Å; L39-Y212 WeakPolarHBondContact O-CE2 3.41Å
40	V	97.5	Very high	96	Very high	64 Å²	64	35 Å²	35	39%	0.388	17%	0.174	S	C	.	.	H	α-helix	trans	-68.5	-43.1	178.1	176	0	0	0	0	111.2	L36 M37 V38 S42 A43 W44 T247	L36-V40 PolarHBondContact O-N 2.78Å; M37-V40 PolarHBondContact O-N 3.37Å; V38-V40 PolarHBondContact O-N 2.9Å; V40-S42 PolarHBondContact O-N 3.42Å; V40-A43 WeakPolarHBondContact O-CB 3.35Å; V40-A43 PolarHBondContact O-N 3.04Å; V40-W44 PolarHBondContact O-N 3.25Å; V40-T247 HydrophobicContact CG2-CG2 4.23Å
41	L	97.1	Very high	96.2	Very high	85 Å²	85	37.7 Å²	37.7	45%	0.445	18%	0.183	S	C	.	.	H	α-helix	trans	-62.8	-42.2	179.4	-178.8	61.3	0	0	0	111.6	M37 V38 A43 W44 V45	M37-L41 VanDerWaalsContact O-CB 3.26Å; M37-L41 WeakPolarHBondContact O-CB 3.34Å; M37-L41 PolarHBondContact O-N 3.49Å; V38-L41 PolarHBondContact O-N 3.3Å; L41-A43 VanDerWaalsContact C-N 3.27Å; L41-A43 PolarHBondContact O-N 2.86Å; L41-W44 HydrophobicContact CD1-CE3 4.32Å; L41-W44 PolarHBondContact O-N 3.26Å; L41-W44 VanDerWaalsContact O-N 3.13Å; L41-V45 HydrophobicContact CD1-CG2 4.07Å; L41-V45 HydrophobicContact CG-CG2 4.07Å; L41-V45 WeakPolarHBondContact O-CG2 3.33Å; L41-V45 PolarHBondContact O-N 2.93Å
42	S	96.7	Very high	96.3	Very high	13 Å²	13	38.9 Å²	38.9	9%	0.091	19%	0.188	C	C	.	.	H	α-helix	trans	-59.7	-35.7	178.5	-72.7	0	0	0	0	112.4	V38 V40 V45 C46	V38-S42 VanDerWaalsContact O-CB 3.28Å; V38-S42 WeakPolarHBondContact O-CB 3.39Å; V38-S42 PolarHBondContact O-N 3.38Å; V38-S42 PolarHBondContact O-OG 2.85Å; V40-S42 PolarHBondContact O-N 3.42Å; S42-V45 PolarHBondContact O-N 3.34Å; S42-C46 VanDerWaalsContact O-CB 3.3Å; S42-C46 WeakPolarHBondContact O-CB 3.38Å; S42-C46 PolarHBondContact O-N 3.37Å; S42-C46 PolarHBondContact O-SG 3.32Å
43	A	97.3	Very high	96.5	Very high	5 Å²	5	38.9 Å²	38.9	4%	0.041	19%	0.188	C	C	.	.	H	α-helix	trans	-63	-45.6	174.8	0	0	0	0	0	111.9	L39 V40 L41 N47 Y212 C243	L39-A43 PolarHBondContact O-N 3.05Å; V40-A43 WeakPolarHBondContact O-CB 3.35Å; V40-A43 PolarHBondContact O-N 3.04Å; L41-A43 VanDerWaalsContact C-N 3.27Å; L41-A43 PolarHBondContact O-N 2.86Å; A43-N47 WeakPolarHBondContact O-CB 3.39Å; A43-N47 PolarHBondContact O-N 2.88Å; A43-N47 VanDerWaalsContact O-N 3.13Å; A43-Y212 HydrophobicContact CB-CD1 4.26Å; A43-Y212 HydrophobicContact CB-CE1 3.64Å; A43-Y212 HydrophobicContact CB-CE2 4.32Å; A43-C243 HydrophobicContact CB-CB 3.67Å
44	W	97.6	Very high	96.7	Very high	128 Å²	128	35.5 Å²	35.5	49%	0.485	18%	0.176	S	C	.	.	H	α-helix	trans	-65.3	-46.3	176.8	178.8	86.6	0	0	0	111.6	V40 L41 N47 H48 I386 I390	V40-W44 PolarHBondContact O-N 3.25Å; L41-W44 HydrophobicContact CD1-CE3 4.32Å; L41-W44 PolarHBondContact O-N 3.26Å; L41-W44 VanDerWaalsContact O-N 3.13Å; W44-N47 PolarHBondContact O-N 2.87Å; W44-H48 WeakPolarHBondContact O-CB 3.42Å; W44-H48 PolarHBondContact O-N 3.45Å; W44-I386 HydrophobicContact CH2-CG2 3.92Å; W44-I386 HydrophobicContact CZ3-CG2 4.49Å; W44-I390 HydrophobicContact CZ3-CD1 4.39Å
45	V	98	Very high	96.7	Very high	8 Å²	8	34 Å²	34	5%	0.048	17%	0.17	C	C	.	.	H	α-helix	trans	-61.1	-47.8	179.7	172.7	0	0	0	0	110.8	L41 S42 N47 H48 T49 L364 I390	L41-V45 HydrophobicContact CD1-CG2 4.07Å; L41-V45 HydrophobicContact CG-CG2 4.07Å; L41-V45 WeakPolarHBondContact O-CG2 3.33Å; L41-V45 PolarHBondContact O-N 2.93Å; S42-V45 PolarHBondContact O-N 3.34Å; V45-N47 PolarHBondContact O-N 2.96Å; V45-H48 WeakPolarHBondContact O-CB 3.4Å; V45-H48 PolarHBondContact O-N 3.29Å; V45-T49 HydrophobicContact CG1-CG2 4.16Å; V45-T49 WeakPolarHBondContact O-CG2 3.34Å; V45-T49 PolarHBondContact O-N 3.37Å; V45-T49 PolarHBondContact O-OG1 2.8Å; V45-L364 HydrophobicContact CG1-CD2 3.42Å; V45-L364 VanDerWaalsContact CG1-CD2 3.42Å; V45-I390 HydrophobicContact CG1-CD1 4.14Å; V45-I390 HydrophobicContact CG1-CG1 4.19Å; V45-I390 HydrophobicContact CG1-CG2 3.77Å; V45-I390 HydrophobicContact CG2-CG1 4.46Å
46	C	97.3	Very high	96.7	Very high	1 Å²	1	34 Å²	34	1%	0.007	17%	0.17	C	C	.	.	H	α-helix	trans	-66	-36.9	-179.2	-68.3	0	0	0	0	112.7	S42 T49 G50 Y212 Q215	S42-C46 VanDerWaalsContact O-CB 3.3Å; S42-C46 WeakPolarHBondContact O-CB 3.38Å; S42-C46 PolarHBondContact O-N 3.37Å; S42-C46 PolarHBondContact O-SG 3.32Å; C46-T49 PolarHBondContact O-OG1 3.02Å; C46-G50 PolarHBondContact O-N 3.35Å; C46-Y212 VanDerWaalsContact SG-CB 3.56Å; C46-Q215 PolarHBondContact O-NE2 3.45Å
47	N	97.8	Very high	96.7	Very high	21 Å²	21	32.4 Å²	32.4	11%	0.112	16%	0.162	C	C	.	.	H	α-helix	trans	-63.5	-45.2	171.5	174	62.7	0	0	0	111.3	A43 W44 V45 G50 R51 G236 H239	A43-N47 WeakPolarHBondContact O-CB 3.39Å; A43-N47 PolarHBondContact O-N 2.88Å; A43-N47 VanDerWaalsContact O-N 3.13Å; W44-N47 PolarHBondContact O-N 2.87Å; V45-N47 PolarHBondContact O-N 2.96Å; N47-G50 PolarHBondContact O-N 3.34Å; N47-R51 WeakPolarHBondContact O-CG 3.43Å; N47-R51 PolarHBondContact O-N 3.3Å; N47-R51 VanDerWaalsContact O-N 3.11Å; N47-G236 PolarHBondContact OD1-N 3.43Å; N47-H239 HydrophobicContact CB-CB 3.91Å
48	H	97.6	Very high	96.6	Very high	30 Å²	30	27.6 Å²	27.6	14%	0.139	14%	0.136	C	C	.	.	H	α-helix	trans	-60.8	-52.5	176.9	176.1	82.2	0	0	0	111.6	W44 V45 G50 R51 K52 D387	W44-H48 WeakPolarHBondContact O-CB 3.42Å; W44-H48 PolarHBondContact O-N 3.45Å; V45-H48 WeakPolarHBondContact O-CB 3.4Å; V45-H48 PolarHBondContact O-N 3.29Å; H48-G50 VanDerWaalsContact C-N 3.31Å; H48-G50 PolarHBondContact O-N 3.44Å; H48-R51 PolarHBondContact O-N 3.1Å; H48-K52 VanDerWaalsContact CE1-CE 3.41Å; H48-K52 WeakPolarHBondContact CE1-CE 3.49Å; H48-K52 WeakPolarHBondContact O-CG 3.29Å; H48-K52 PolarHBondContact O-N 2.87Å; H48-D387 IonicContact CD2-OD1 2.62Å; H48-D387 IonicContact CE1-OD1 3.14Å; H48-D387 IonicContact NE2-OD1 2.59Å; H48-D387 PolarHBondContact NE2-OD1 2.85Å
49	T	97.8	Very high	96.3	Very high	0 Å²	0	30.5 Å²	30.5	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-65.4	-34.6	-178.9	61.2	0	0	0	0	112.1	V45 C46 K52 L53 Q215 T363 P367 I390	V45-T49 HydrophobicContact CG1-CG2 4.16Å; V45-T49 WeakPolarHBondContact O-CG2 3.34Å; V45-T49 PolarHBondContact O-N 3.37Å; V45-T49 PolarHBondContact O-OG1 2.8Å; C46-T49 PolarHBondContact O-OG1 3.02Å; T49-K52 PolarHBondContact O-N 2.91Å; T49-L53 WeakPolarHBondContact O-CB 3.44Å; T49-L53 PolarHBondContact O-N 3.32Å; T49-Q215 PolarHBondContact OG1-NE2 2.66Å; T49-Q215 VanDerWaalsContact OG1-NE2 3.11Å; T49-T363 WeakPolarHBondContact CB-O 3.17Å; T49-T363 WeakPolarHBondContact CG2-O 3.4Å; T49-T363 PolarHBondContact OG1-O 3.19Å; T49-P367 HydrophobicContact CG2-CB 4.5Å; T49-I390 HydrophobicContact CG2-CD1 4.45Å; T49-I390 HydrophobicContact CG2-CG2 4.01Å
50	G	97.4	Very high	95.6	Very high	0 Å²	0	34 Å²	34	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-61.2	-44	173	0	0	0	0	0	113	C46 N47 H48 L53 V54	C46-G50 PolarHBondContact O-N 3.35Å; N47-G50 PolarHBondContact O-N 3.34Å; H48-G50 VanDerWaalsContact C-N 3.31Å; H48-G50 PolarHBondContact O-N 3.44Å; G50-L53 PolarHBondContact O-N 3.32Å; G50-V54 PolarHBondContact O-N 3.22Å; G50-V54 VanDerWaalsContact O-N 3.09Å
51	R	97.1	Very high	94.6	Very high	90 Å²	90	36.5 Å²	36.5	34%	0.34	17%	0.172	S	C	.	.	H	α-helix	trans	-64	-42.7	173.3	-67.4	-179.1	-177.6	177.6	-6	111.9	N47 H48 L53 V54 A55 D232 L235	N47-R51 WeakPolarHBondContact O-CG 3.43Å; N47-R51 PolarHBondContact O-N 3.3Å; N47-R51 VanDerWaalsContact O-N 3.11Å; H48-R51 PolarHBondContact O-N 3.1Å; R51-L53 VanDerWaalsContact C-N 3.34Å; R51-L53 PolarHBondContact O-N 3.13Å; R51-V54 PolarHBondContact O-N 3.19Å; R51-A55 WeakPolarHBondContact O-CB 3.42Å; R51-A55 PolarHBondContact O-N 3.45Å; R51-D232 PolarHBondContact NH2-O 2.85Å; R51-L235 HydrophobicContact CG-CD2 3.91Å
52	K	96.1	Very high	93.2	Very high	26 Å²	26	42.3 Å²	42.3	11%	0.113	19%	0.188	C	C	.	.	H	α-helix	trans	-64.2	-39.2	178.1	-65.9	-38.4	-163.7	168.7	0	112.2	H48 T49 A55 C56 H371 E383	H48-K52 VanDerWaalsContact CE1-CE 3.41Å; H48-K52 WeakPolarHBondContact CE1-CE 3.49Å; H48-K52 WeakPolarHBondContact O-CG 3.29Å; H48-K52 PolarHBondContact O-N 2.87Å; T49-K52 PolarHBondContact O-N 2.91Å; K52-A55 PolarHBondContact O-N 3.49Å; K52-C56 PolarHBondContact O-N 3.39Å; K52-C56 VanDerWaalsContact O-N 3.14Å; K52-C56 PolarHBondContact O-SG 2.83Å; K52-H371 HydrophobicContact CB-CB 4.06Å; K52-H371 WeakPolarHBondContact CD-NE2 3.28Å; K52-H371 WeakPolarHBondContact CE-CE1 3.3Å; K52-H371 PolarHBondContact NZ-CE1 3.03Å; K52-H371 VanDerWaalsContact NZ-CE1 3.3Å; K52-H371 PolarHBondContact NZ-NE2 3.34Å; K52-E383 IonicContact NZ-OE1 3.82Å; K52-E383 PolarHBondContact NZ-OE1 3.41Å
53	L	96.8	Very high	91.4	Very high	0 Å²	0	45.7 Å²	45.7	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-60.6	-49.9	174.6	-177.2	67.6	0	0	0	111.3	T49 G50 R51 A55 C56 Y78 I81 Q215 P219 P367 F370	T49-L53 WeakPolarHBondContact O-CB 3.44Å; T49-L53 PolarHBondContact O-N 3.32Å; G50-L53 PolarHBondContact O-N 3.32Å; R51-L53 VanDerWaalsContact C-N 3.34Å; R51-L53 PolarHBondContact O-N 3.13Å; L53-A55 VanDerWaalsContact C-N 3.33Å; L53-A55 PolarHBondContact O-N 2.82Å; L53-C56 VanDerWaalsContact O-CB 3.32Å; L53-C56 WeakPolarHBondContact O-CB 3.06Å; L53-C56 PolarHBondContact O-N 2.89Å; L53-C56 VanDerWaalsContact O-N 3.08Å; L53-Y78 HydrophobicContact CD1-CD2 4.11Å; L53-Y78 HydrophobicContact CD1-CE1 4.23Å; L53-Y78 HydrophobicContact CD1-CE2 3.72Å; L53-Y78 HydrophobicContact CD2-CD2 3.81Å; L53-Y78 HydrophobicContact CD2-CE2 3.42Å; L53-Y78 VanDerWaalsContact CD2-CE2 3.42Å; L53-Y78 HydrophobicContact CG-CE2 4.22Å; L53-I81 HydrophobicContact CD1-CD1 3.61Å; L53-I81 HydrophobicContact CG-CD1 4.26Å; L53-Q215 HydrophobicContact CD2-CB 3.95Å; L53-Q215 HydrophobicContact CD2-CG 4.39Å; L53-Q215 WeakPolarHBondContact CD2-O 3.32Å; L53-P219 HydrophobicContact CD2-CG 4.09Å; L53-P219 HydrophobicContact CG-CG 4.38Å; L53-P367 HydrophobicContact CB-CB 4.24Å; L53-F370 HydrophobicContact CD1-CD2 4.15Å
54	V	96.1	Very high	89.3	Confident	8 Å²	8	48.9 Å²	48.9	5%	0.048	25%	0.245	C	C	.	.	H	α-helix	trans	-65.4	-37.2	177.9	170.1	0	0	0	0	111.6	G50 R51 C56 L57 Y58 L218 E222 F231	G50-V54 PolarHBondContact O-N 3.22Å; G50-V54 VanDerWaalsContact O-N 3.09Å; R51-V54 PolarHBondContact O-N 3.19Å; V54-C56 PolarHBondContact O-N 3.49Å; V54-C56 VanDerWaalsContact O-N 3.17Å; V54-L57 HydrophobicContact CB-CD1 4.44Å; V54-L57 HydrophobicContact CG1-CD1 4.32Å; V54-L57 HydrophobicContact CG2-CD1 4.32Å; V54-L57 VanDerWaalsContact O-CB 3.24Å; V54-L57 WeakPolarHBondContact O-CB 3.49Å; V54-L57 PolarHBondContact O-N 3.08Å; V54-Y58 HydrophobicContact CG1-CE2 4.23Å; V54-Y58 WeakPolarHBondContact O-CD2 3.26Å; V54-L218 HydrophobicContact CG2-CB 4.08Å; V54-E222 HydrophobicContact CG1-CG 4.01Å; V54-F231 HydrophobicContact CB-CD1 4.29Å; V54-F231 HydrophobicContact CB-CE1 3.76Å; V54-F231 HydrophobicContact CB-CZ 4.22Å; V54-F231 HydrophobicContact CG1-CD1 4.01Å; V54-F231 HydrophobicContact CG1-CE1 3.99Å; V54-F231 HydrophobicContact CG2-CD1 4.27Å; V54-F231 HydrophobicContact CG2-CE1 3.46Å; V54-F231 VanDerWaalsContact CG2-CE1 3.46Å; V54-F231 HydrophobicContact CG2-CE2 4.12Å; V54-F231 HydrophobicContact CG2-CZ 3.38Å
55	A	94.4	Very high	87.3	Confident	34 Å²	34	53.6 Å²	53.6	28%	0.281	27%	0.269	S	S	.	.	H	α-helix	trans	-60	-26.7	173.5	0	0	0	0	0	113	R51 K52 L53 L57 Y58 R375	R51-A55 WeakPolarHBondContact O-CB 3.42Å; R51-A55 PolarHBondContact O-N 3.45Å; K52-A55 PolarHBondContact O-N 3.49Å; L53-A55 VanDerWaalsContact C-N 3.33Å; L53-A55 PolarHBondContact O-N 2.82Å; A55-L57 VanDerWaalsContact C-N 3.26Å; A55-L57 PolarHBondContact O-N 3.14Å; A55-Y58 PolarHBondContact O-N 3.17Å; A55-R375 PolarHBondContact O-NH2 3.29Å
56	C	94.7	Very high	85.5	Confident	1 Å²	1	56.6 Å²	56.6	1%	0.007	29%	0.29	C	S	.	.	T	Hydrogen-bonded Turn	trans	-73.9	-14.5	174.5	-64.7	0	0	0	0	113.4	K52 L53 V54 Y58 R75 I81 L374	K52-C56 PolarHBondContact O-N 3.39Å; K52-C56 VanDerWaalsContact O-N 3.14Å; K52-C56 PolarHBondContact O-SG 2.83Å; L53-C56 VanDerWaalsContact O-CB 3.32Å; L53-C56 WeakPolarHBondContact O-CB 3.06Å; L53-C56 PolarHBondContact O-N 2.89Å; L53-C56 VanDerWaalsContact O-N 3.08Å; V54-C56 PolarHBondContact O-N 3.49Å; V54-C56 VanDerWaalsContact O-N 3.17Å; C56-Y58 PolarHBondContact O-N 3.29Å; C56-R75 WeakPolarHBondContact O-CD 3.44Å; C56-R75 PolarHBondContact O-NH1 2.87Å; C56-I81 HydrophobicContact CB-CD1 4.1Å; C56-I81 HydrophobicContact CB-CG1 4.34Å; C56-I81 HydrophobicContact CB-CG2 3.77Å; C56-L374 HydrophobicContact CB-CD1 3.97Å
57	L	94.8	Very high	83.8	Confident	0 Å²	0	62.2 Å²	62.2	0%	0	33%	0.329	C	S	.	.	T	Hydrogen-bonded Turn	trans	-72.5	-19.1	175.1	-60	172	0	0	0	113.2	V54 A55 R73 V74 R75 I81 P219	V54-L57 HydrophobicContact CB-CD1 4.44Å; V54-L57 HydrophobicContact CG1-CD1 4.32Å; V54-L57 HydrophobicContact CG2-CD1 4.32Å; V54-L57 VanDerWaalsContact O-CB 3.24Å; V54-L57 WeakPolarHBondContact O-CB 3.49Å; V54-L57 PolarHBondContact O-N 3.08Å; A55-L57 VanDerWaalsContact C-N 3.26Å; A55-L57 PolarHBondContact O-N 3.14Å; L57-R73 HydrophobicContact CB-CG 4.4Å; L57-V74 PolarHBondContact O-N 2.98Å; L57-R75 HydrophobicContact CD2-CB 3.94Å; L57-R75 PolarHBondContact O-N 3.21Å; L57-R75 VanDerWaalsContact O-N 3.15Å; L57-I81 HydrophobicContact CD2-CD1 3.64Å; L57-I81 HydrophobicContact CD2-CG1 3.81Å; L57-I81 HydrophobicContact CG-CD1 4.23Å; L57-P219 HydrophobicContact CD1-CB 3.97Å; L57-P219 HydrophobicContact CD2-CB 4.15Å
58	Y	93.8	Very high	82.2	Confident	39 Å²	39	68.2 Å²	68.2	15%	0.153	36%	0.355	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103	150.1	-173.9	-69.1	-92.4	0	0	0	111.9	V54 A55 C56 K71 V72 R73 E222 R228 R375	V54-Y58 HydrophobicContact CG1-CE2 4.23Å; V54-Y58 WeakPolarHBondContact O-CD2 3.26Å; A55-Y58 PolarHBondContact O-N 3.17Å; C56-Y58 PolarHBondContact O-N 3.29Å; Y58-K71 HydrophobicContact CD1-CB 4.14Å; Y58-V72 CarbonylContact C-O 3.48Å; Y58-V72 WeakPolarHBondContact CA-O 3.49Å; Y58-R73 HydrophobicContact CD1-CB 3.93Å; Y58-R73 HydrophobicContact CE1-CB 3.62Å; Y58-R73 HydrophobicContact CE1-CG 4.4Å; Y58-E222 PolarHBondContact OH-OE1 3.23Å; Y58-R228 WeakPolarHBondContact OH-CD 3.34Å; Y58-R375 PolarHBondContact O-NH2 3.38Å
59	E	89.4	Confident	81	Confident	88 Å²	88	69.6 Å²	69.6	41%	0.411	37%	0.365	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.6	156.7	162.4	-78	-176.3	-173.5	0	0	109.8	K71 V72 V74 R75	E59-K71 CarbonylContact O-C 3.5Å; E59-K71 WeakPolarHBondContact O-CA 3.38Å; E59-V72 PolarHBondContact N-O 2.9Å; E59-V72 PolarHBondContact O-N 3.17Å; E59-V74 HydrophobicContact CB-CG1 4.19Å; E59-V74 HydrophobicContact CB-CG2 4.02Å; E59-V74 HydrophobicContact CG-CG2 3.59Å; E59-R75 IonicContact OE1-CZ 2.66Å; E59-R75 IonicContact OE1-NH1 3.92Å; E59-R75 IonicContact OE1-NH2 2.94Å; E59-R75 PolarHBondContact OE1-NH2 3.37Å
60	E	83.2	Confident	80.1	Confident	73 Å²	73	71.5 Å²	71.5	34%	0.341	38%	0.378	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-99.2	116	176.3	-72.5	176.3	172.2	0	0	108.1	V69 S70 K71 R378	E60-V69 HydrophobicContact CB-CG1 3.6Å; E60-V69 HydrophobicContact CG-CG1 3.69Å; E60-S70 WeakPolarHBondContact CA-O 3.49Å; E60-K71 HydrophobicContact CG-CG 4.16Å; E60-R378 IonicContact OE2-CZ 3.55Å; E60-R378 IonicContact OE2-NH1 2.71Å; E60-R378 PolarHBondContact OE2-NH1 3Å
61	E	76.1	Confident	79.5	Confident	116 Å²	116	78.5 Å²	78.5	54%	0.542	41%	0.409	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.9	128.8	169.8	-77.8	-170.3	157.2	0	0	109.5	S70 V72	E61-S70 PolarHBondContact N-O 3.45Å; E61-S70 PolarHBondContact O-N 3.15Å; E61-S70 PolarHBondContact O-OG 3.39Å; E61-V72 HydrophobicContact CB-CG2 4.45Å; E61-V72 HydrophobicContact CG-CG2 4.36Å
62	R	67.6	Low	79.1	Confident	208 Å²	208	76.8 Å²	76.8	79%	0.785	41%	0.408	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-89.8	108.9	164.9	-101.6	-179.1	175.9	171.5	-0.8	107.7	G64 V69	R62-G64 PolarHBondContact O-N 3.42Å; R62-V69 HydrophobicContact CG-CG2 4.33Å
63	S	58.2	Low	78.9	Confident	83 Å²	83	76.9 Å²	76.9	58%	0.58	41%	0.408	S	S	*	.			trans	-69.3	121.4	171.6	-163.9	0	0	0	0	109.2	K65 S66	S63-K65 PolarHBondContact O-N 3.36Å; S63-K65 VanDerWaalsContact O-N 3.13Å; S63-S66 PolarHBondContact O-N 3.49Å
64	G	54.8	Low	78.6	Confident	73 Å²	73	79.9 Å²	79.9	75%	0.753	43%	0.426	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.1	118.3	-173.3	0	0	0	0	0	112.4	R62	R62-G64 PolarHBondContact O-N 3.42Å
65	K	54.9	Low	78.5	Confident	227 Å²	227	80.4 Å²	80.4	99%	0.987	43%	0.427	S	S	*	.	T	Hydrogen-bonded Turn	trans	92.6	-7.1	179	-59.8	176.8	176.3	175.3	0	118.4	S63	S63-K65 PolarHBondContact O-N 3.36Å; S63-K65 VanDerWaalsContact O-N 3.13Å
66	S	59.6	Low	78.2	Confident	71 Å²	71	84.1 Å²	84.1	50%	0.497	44%	0.438	S	S	.	.			trans	-108.6	144	171.4	-170.1	0	0	0	0	111.4	S63 F68	S63-S66 PolarHBondContact O-N 3.49Å; S66-F68 PolarHBondContact O-N 2.92Å; S66-F68 PolarHBondContact OG-N 3.4Å
67	S	62.1	Low	78	Confident	118 Å²	118	85.8 Å²	85.8	83%	0.825	45%	0.45	S	S	*	.	S	Bend	trans	-72.2	-3.2	173.9	77.4	0	0	0	0	112.9	V69	S67-V69 PolarHBondContact O-N 3.46Å
68	F	64.2	Low	77.8	Confident	148 Å²	148	86 Å²	86	65%	0.649	45%	0.451	S	S	*	.			trans	-72.3	119.1	-180	-167.4	-102.8	0	0	0	111.4	S66	S66-F68 PolarHBondContact O-N 2.92Å; S66-F68 PolarHBondContact OG-N 3.4Å
69	V	73.2	Confident	77.7	Confident	59 Å²	59	86 Å²	86	36%	0.358	45%	0.453	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.9	112.2	175.8	179.1	0	0	0	0	108.2	E60 R62 S67	E60-V69 HydrophobicContact CB-CG1 3.6Å; E60-V69 HydrophobicContact CG-CG1 3.69Å; R62-V69 HydrophobicContact CG-CG2 4.33Å; S67-V69 PolarHBondContact O-N 3.46Å
70	S	78.3	Confident	77.8	Confident	39 Å²	39	84.3 Å²	84.3	27%	0.273	45%	0.446	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.8	134.1	175.5	53.6	0	0	0	0	110.9	E60 E61	E60-S70 WeakPolarHBondContact CA-O 3.49Å; E61-S70 PolarHBondContact N-O 3.45Å; E61-S70 PolarHBondContact O-N 3.15Å; E61-S70 PolarHBondContact O-OG 3.39Å
71	K	84.3	Confident	78.3	Confident	148 Å²	148	80.8 Å²	80.8	64%	0.643	43%	0.43	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-86.8	119.2	172.6	-67.8	-179.9	-177.9	177.2	0	109.5	Y58 E59 E60	Y58-K71 HydrophobicContact CD1-CB 4.14Å; E59-K71 CarbonylContact O-C 3.5Å; E59-K71 WeakPolarHBondContact O-CA 3.38Å; E60-K71 HydrophobicContact CG-CG 4.16Å
72	V	88.6	Confident	79.1	Confident	53 Å²	53	76.4 Å²	76.4	32%	0.321	41%	0.409	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.4	132.5	177.3	-177.7	0	0	0	0	108.7	Y58 E59 E61 V74	Y58-V72 CarbonylContact C-O 3.48Å; Y58-V72 WeakPolarHBondContact CA-O 3.49Å; E59-V72 PolarHBondContact N-O 2.9Å; E59-V72 PolarHBondContact O-N 3.17Å; E61-V72 HydrophobicContact CB-CG2 4.45Å; E61-V72 HydrophobicContact CG-CG2 4.36Å; V72-V74 HydrophobicContact CG1-CG1 4.36Å; V72-V74 PolarHBondContact O-N 3.11Å
73	R	91.3	Very high	80.2	Confident	28 Å²	28	68.2 Å²	68.2	11%	0.106	38%	0.381	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.3	116.1	175.4	-175.3	173.8	175.5	174.9	-0.4	109.2	L57 Y58 R75 H76 P219 E222	L57-R73 HydrophobicContact CB-CG 4.4Å; Y58-R73 HydrophobicContact CD1-CB 3.93Å; Y58-R73 HydrophobicContact CE1-CB 3.62Å; Y58-R73 HydrophobicContact CE1-CG 4.4Å; R73-R75 VanDerWaalsContact CG-O 3.27Å; R73-R75 WeakPolarHBondContact CG-O 3.35Å; R73-R75 PolarHBondContact NE-O 3.09Å; R73-H76 PolarHBondContact NH2-O 3.01Å; R73-P219 PolarHBondContact NH2-O 2.76Å; R73-E222 IonicContact CZ-OE2 3.88Å; R73-E222 IonicContact NE-OE2 2.67Å; R73-E222 IonicContact NH1-OE2 3.41Å; R73-E222 PolarHBondContact NH1-OE2 2.96Å; R73-E222 IonicContact NH2-OE2 3.49Å
74	V	91.6	Very high	81.8	Confident	64 Å²	64	64.9 Å²	64.9	39%	0.388	36%	0.359	S	S	.	.			trans	-113.1	-7.1	-178.6	-57.4	0	0	0	0	112.9	L57 E59 V72	L57-V74 PolarHBondContact O-N 2.98Å; E59-V74 HydrophobicContact CB-CG1 4.19Å; E59-V74 HydrophobicContact CB-CG2 4.02Å; E59-V74 HydrophobicContact CG-CG2 3.59Å; V72-V74 HydrophobicContact CG1-CG1 4.36Å; V72-V74 PolarHBondContact O-N 3.11Å
75	R	92.9	Very high	83.5	Confident	19 Å²	19	61.9 Å²	61.9	7%	0.072	33%	0.326	C	S	.	.			trans	-129.3	147.2	179.5	-43.6	-176	177.1	67.5	13.6	110	C56 L57 E59 R73 D80 I81	C56-R75 WeakPolarHBondContact O-CD 3.44Å; C56-R75 PolarHBondContact O-NH1 2.87Å; L57-R75 HydrophobicContact CD2-CB 3.94Å; L57-R75 PolarHBondContact O-N 3.21Å; L57-R75 VanDerWaalsContact O-N 3.15Å; E59-R75 IonicContact OE1-CZ 2.66Å; E59-R75 IonicContact OE1-NH1 3.92Å; E59-R75 IonicContact OE1-NH2 2.94Å; E59-R75 PolarHBondContact OE1-NH2 3.37Å; R73-R75 VanDerWaalsContact CG-O 3.27Å; R73-R75 WeakPolarHBondContact CG-O 3.35Å; R73-R75 PolarHBondContact NE-O 3.09Å; R75-D80 HydrophobicContact CB-CB 3.78Å; R75-D80 HydrophobicContact CG-CB 4.39Å; R75-I81 HydrophobicContact CB-CG1 4.5Å
76	H	88.6	Confident	85.1	Confident	111 Å²	111	51.3 Å²	51.3	51%	0.514	28%	0.281	S	S	.	.			trans	-120	-28.4	-174.5	-63.2	-76.6	0	0	0	113.2	R73 D80	R73-H76 PolarHBondContact NH2-O 3.01Å; H76-D80 WeakPolarHBondContact CA-OD2 3.32Å; H76-D80 PolarHBondContact N-OD2 3.36Å
77	S	90.8	Very high	86.2	Confident	37 Å²	37	55.1 Å²	55.1	26%	0.259	29%	0.288	S	S	.	.	S	Bend	trans	-122.1	166.8	-175.8	76.6	0	0	0	0	113.2	Q79 D80 I81	S77-Q79 VanDerWaalsContact C-N 3.27Å; S77-Q79 PolarHBondContact O-N 2.87Å; S77-Q79 PolarHBondContact OG-N 3.48Å; S77-D80 PolarHBondContact N-OD2 3.18Å; S77-D80 PolarHBondContact O-N 3.05Å; S77-D80 PolarHBondContact OG-N 3.45Å; S77-D80 PolarHBondContact OG-OD1 2.53Å; S77-D80 PolarHBondContact OG-OD2 3.36Å; S77-I81 PolarHBondContact O-N 3.36Å
78	Y	90.4	Very high	86.7	Confident	3 Å²	3	53.6 Å²	53.6	1%	0.012	29%	0.292	C	S	.	.	H	α-helix	trans	-61.1	-39.6	171.4	-147.9	-63.4	0	0	0	110.8	L53 I81 M82 I101 Q215 P219 M362 L366 P367 F370	L53-Y78 HydrophobicContact CD1-CD2 4.11Å; L53-Y78 HydrophobicContact CD1-CE1 4.23Å; L53-Y78 HydrophobicContact CD1-CE2 3.72Å; L53-Y78 HydrophobicContact CD2-CD2 3.81Å; L53-Y78 HydrophobicContact CD2-CE2 3.42Å; L53-Y78 VanDerWaalsContact CD2-CE2 3.42Å; L53-Y78 HydrophobicContact CG-CE2 4.22Å; Y78-I81 PolarHBondContact O-N 2.89Å; Y78-M82 PolarHBondContact O-N 2.98Å; Y78-I101 HydrophobicContact CD1-CD1 3.95Å; Y78-I101 HydrophobicContact CD1-CG2 3.64Å; Y78-I101 HydrophobicContact CE1-CD1 4.21Å; Y78-I101 HydrophobicContact CE1-CG2 4.41Å; Y78-I101 HydrophobicContact CG-CG2 4.16Å; Y78-Q215 HydrophobicContact CE2-CB 4.31Å; Y78-P219 HydrophobicContact CD2-CG 4.48Å; Y78-M362 HydrophobicContact CD1-CE 4.02Å; Y78-M362 HydrophobicContact CD2-CE 3.89Å; Y78-M362 HydrophobicContact CE1-CE 3.81Å; Y78-M362 HydrophobicContact CE2-CE 3.69Å; Y78-M362 HydrophobicContact CG-CE 4.06Å; Y78-M362 PolarHBondContact OH-O 3.33Å; Y78-L366 HydrophobicContact CE1-CB 4.01Å; Y78-L366 HydrophobicContact CE1-CD1 3.96Å; Y78-L366 WeakPolarHBondContact OH-CB 3.43Å; Y78-P367 WeakPolarHBondContact OH-CD 3.3Å; Y78-P367 WeakPolarHBondContact OH-CG 3.48Å; Y78-F370 AromaticContact CD1-CE2 3.76Å; Y78-F370 HydrophobicContact CD1-CE2 3.76Å; Y78-F370 HydrophobicContact CD1-CZ 4.38Å; Y78-F370 HydrophobicContact CE1-CD2 4.29Å; Y78-F370 AromaticContact CE1-CE2 3.32Å; Y78-F370 HydrophobicContact CE1-CE2 3.32Å; Y78-F370 AromaticContact CE1-CZ 3.96Å; Y78-F370 HydrophobicContact CE1-CZ 3.96Å
79	Q	92.3	Very high	87.4	Confident	41 Å²	41	50.6 Å²	50.6	19%	0.192	28%	0.282	C	S	.	.	H	α-helix	trans	-57.9	-45.8	173	172	-178.9	-4.8	0	0	112	S77 I81 M82 D83 N102	S77-Q79 VanDerWaalsContact C-N 3.27Å; S77-Q79 PolarHBondContact O-N 2.87Å; S77-Q79 PolarHBondContact OG-N 3.48Å; Q79-I81 PolarHBondContact O-N 3.11Å; Q79-M82 WeakPolarHBondContact O-CA 3.38Å; Q79-M82 WeakPolarHBondContact O-CB 3.45Å; Q79-M82 PolarHBondContact O-N 3.36Å; Q79-D83 PolarHBondContact O-N 2.87Å; Q79-N102 PolarHBondContact OE1-ND2 3.38Å
80	D	91.3	Very high	87.5	Confident	51 Å²	51	57.1 Å²	57.1	27%	0.273	30%	0.3	S	S	.	.	H	α-helix	trans	-61.9	-32.7	-177.5	-59.7	-13.5	0	0	0	112.1	R75 H76 S77 A84	R75-D80 HydrophobicContact CB-CB 3.78Å; R75-D80 HydrophobicContact CG-CB 4.39Å; H76-D80 WeakPolarHBondContact CA-OD2 3.32Å; H76-D80 PolarHBondContact N-OD2 3.36Å; S77-D80 PolarHBondContact N-OD2 3.18Å; S77-D80 PolarHBondContact O-N 3.05Å; S77-D80 PolarHBondContact OG-N 3.45Å; S77-D80 PolarHBondContact OG-OD1 2.53Å; S77-D80 PolarHBondContact OG-OD2 3.36Å; D80-A84 WeakPolarHBondContact O-CB 3.39Å; D80-A84 PolarHBondContact O-N 3.48Å; D80-A84 VanDerWaalsContact O-N 3.1Å
81	I	93.3	Very high	87.3	Confident	0 Å²	0	61 Å²	61	0%	0	33%	0.325	C	S	.	.	H	α-helix	trans	-66.1	-44.3	174.9	-57.3	169.7	0	0	0	110.2	L53 C56 L57 R75 S77 Y78 Q79 A84 C85 F370 L374	L53-I81 HydrophobicContact CD1-CD1 3.61Å; L53-I81 HydrophobicContact CG-CD1 4.26Å; C56-I81 HydrophobicContact CB-CD1 4.1Å; C56-I81 HydrophobicContact CB-CG1 4.34Å; C56-I81 HydrophobicContact CB-CG2 3.77Å; L57-I81 HydrophobicContact CD2-CD1 3.64Å; L57-I81 HydrophobicContact CD2-CG1 3.81Å; L57-I81 HydrophobicContact CG-CD1 4.23Å; R75-I81 HydrophobicContact CB-CG1 4.5Å; S77-I81 PolarHBondContact O-N 3.36Å; Y78-I81 PolarHBondContact O-N 2.89Å; Q79-I81 PolarHBondContact O-N 3.11Å; I81-A84 PolarHBondContact O-N 2.82Å; I81-C85 PolarHBondContact O-N 2.97Å; I81-C85 PolarHBondContact O-SG 2.82Å; I81-F370 HydrophobicContact CB-CD2 4.06Å; I81-F370 HydrophobicContact CB-CE2 4.18Å; I81-F370 HydrophobicContact CG2-CB 3.72Å; I81-F370 HydrophobicContact CG2-CD1 4.36Å; I81-F370 HydrophobicContact CG2-CD2 3.31Å; I81-F370 HydrophobicContact CG2-CE2 3.89Å; I81-F370 HydrophobicContact CG2-CG 3.57Å; I81-L374 HydrophobicContact CG2-CD1 3.84Å
82	M	93.3	Very high	87.1	Confident	23 Å²	23	59.7 Å²	59.7	11%	0.113	33%	0.325	C	S	.	.	H	α-helix	trans	-65.3	-43.9	176.8	-178.5	63.5	139.5	0	0	112.5	Y78 Q79 A84 C85 C86 I101 F370	Y78-M82 PolarHBondContact O-N 2.98Å; Q79-M82 WeakPolarHBondContact O-CA 3.38Å; Q79-M82 WeakPolarHBondContact O-CB 3.45Å; Q79-M82 PolarHBondContact O-N 3.36Å; M82-A84 PolarHBondContact O-N 2.91Å; M82-C85 CarbonylContact O-C 3.49Å; M82-C85 WeakPolarHBondContact O-CA 3.24Å; M82-C85 WeakPolarHBondContact O-CB 3.27Å; M82-C85 PolarHBondContact O-N 3.31Å; M82-C86 WeakPolarHBondContact O-CB 3.39Å; M82-C86 PolarHBondContact O-N 2.86Å; M82-C86 PolarHBondContact O-SG 3.33Å; M82-C86 VanDerWaalsContact O-SG 3.34Å; M82-I101 HydrophobicContact CB-CD1 3.21Å; M82-I101 HydrophobicContact CB-CG1 4.37Å; M82-I101 HydrophobicContact CE-CD1 3.99Å; M82-I101 HydrophobicContact CE-CG1 4.18Å; M82-I101 HydrophobicContact CG-CD1 3.41Å; M82-I101 VanDerWaalsContact CG-CD1 3.41Å; M82-I101 HydrophobicContact CG-CG1 4.2Å; M82-I101 HydrophobicContact SD-CD1 3.93Å; M82-F370 HydrophobicContact CB-CE1 4.34Å; M82-F370 HydrophobicContact CB-CZ 3.99Å; M82-F370 HydrophobicContact SD-CE1 3.66Å; M82-F370 HydrophobicContact SD-CZ 4.01Å
83	D	91.1	Very high	86.9	Confident	36 Å²	36	63.8 Å²	63.8	19%	0.193	34%	0.335	C	S	.	.	H	α-helix	trans	-56.4	-44	175.9	-72.4	-18.4	0	0	0	110.4	Q79 C86 K87	Q79-D83 PolarHBondContact O-N 2.87Å; D83-C86 PolarHBondContact O-N 3.28Å; D83-K87 WeakPolarHBondContact O-CG 3.31Å; D83-K87 PolarHBondContact O-N 3.45Å
84	A	91.2	Very high	86.5	Confident	14 Å²	14	64.2 Å²	64.2	12%	0.116	34%	0.342	C	S	.	.	H	α-helix	trans	-66.1	-35.6	174.3	0	0	0	0	0	113.6	D80 I81 M82 C86 L374	D80-A84 WeakPolarHBondContact O-CB 3.39Å; D80-A84 PolarHBondContact O-N 3.48Å; D80-A84 VanDerWaalsContact O-N 3.1Å; I81-A84 PolarHBondContact O-N 2.82Å; M82-A84 PolarHBondContact O-N 2.91Å; A84-C86 VanDerWaalsContact C-N 3.33Å; A84-L374 HydrophobicContact CB-CD2 4.3Å
85	C	90	Very high	86.3	Confident	10 Å²	10	65.2 Å²	65.2	7%	0.068	35%	0.348	C	S	.	.	H	α-helix	trans	-68.3	-32.4	174.4	-69.7	0	0	0	0	112.3	I81 M82 L89 F370 K373 L374	I81-C85 PolarHBondContact O-N 2.97Å; I81-C85 PolarHBondContact O-SG 2.82Å; M82-C85 CarbonylContact O-C 3.49Å; M82-C85 WeakPolarHBondContact O-CA 3.24Å; M82-C85 WeakPolarHBondContact O-CB 3.27Å; M82-C85 PolarHBondContact O-N 3.31Å; C85-L89 WeakPolarHBondContact O-CD1 3.33Å; C85-F370 HydrophobicContact CB-CD1 4.22Å; C85-F370 WeakPolarHBondContact SG-CD1 3.24Å; C85-K373 HydrophobicContact CB-CD 4.18Å; C85-K373 WeakPolarHBondContact O-CE 3.45Å; C85-K373 PolarHBondContact O-NZ 2.98Å; C85-L374 VanDerWaalsContact SG-CG 3.58Å
86	C	87.9	Confident	86.1	Confident	5 Å²	5	67.9 Å²	67.9	3%	0.034	37%	0.366	C	S	.	.	H	α-helix	trans	-86.9	-16.8	-179.1	-65.3	0	0	0	0	113.4	M82 D83 A84 G88 L89 W93 S94	M82-C86 WeakPolarHBondContact O-CB 3.39Å; M82-C86 PolarHBondContact O-N 2.86Å; M82-C86 PolarHBondContact O-SG 3.33Å; M82-C86 VanDerWaalsContact O-SG 3.34Å; D83-C86 PolarHBondContact O-N 3.28Å; A84-C86 VanDerWaalsContact C-N 3.33Å; C86-G88 PolarHBondContact O-N 2.94Å; C86-L89 PolarHBondContact O-N 3.3Å; C86-L89 VanDerWaalsContact O-N 3.15Å; C86-W93 HydrophobicContact CB-CB 4.48Å; C86-W93 HydrophobicContact CB-CE3 4.48Å; C86-S94 VanDerWaalsContact CB-CA 3.48Å
87	K	82.8	Confident	86.1	Confident	150 Å²	150	62.8 Å²	62.8	65%	0.652	34%	0.343	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.8	125.8	173.8	-83.2	175.6	-170.2	-178.8	0	110.9	D83	D83-K87 WeakPolarHBondContact O-CG 3.31Å; D83-K87 PolarHBondContact O-N 3.45Å
88	G	73.9	Confident	86.1	Confident	87 Å²	87	61 Å²	61	90%	0.897	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	85.4	-1.3	177.4	0	0	0	0	0	115.9	C86	C86-G88 PolarHBondContact O-N 2.94Å
89	L	78.8	Confident	86	Confident	85 Å²	85	67 Å²	67	45%	0.445	35%	0.354	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.5	-68.6	170.1	-85.3	77.1	0	0	0	110.2	C85 C86 W93	C85-L89 WeakPolarHBondContact O-CD1 3.33Å; C86-L89 PolarHBondContact O-N 3.3Å; C86-L89 VanDerWaalsContact O-N 3.15Å; L89-W93 HydrophobicContact CD2-CE3 4.07Å; L89-W93 HydrophobicContact CD2-CZ3 4.12Å
90	W	76	Confident	86	Confident	195 Å²	195	70.7 Å²	70.7	74%	0.739	37%	0.372	S	S	*	.			trans	-147.4	153.1	-173.4	-82.9	64.7	0	0	0	111.3	N92 W93	W90-N92 VanDerWaalsContact C-N 3.25Å; W90-N92 PolarHBondContact O-N 3.43Å; W90-W93 HydrophobicContact CB-CB 4.12Å; W90-W93 HydrophobicContact CB-CG 4.31Å; W90-W93 PolarHBondContact O-N 3.11Å
91	P	72.8	Confident	86.1	Confident	122 Å²	122	68.5 Å²	68.5	79%	0.792	36%	0.36	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.1	-13.1	-167.6	16.3	-27.4	0	0	0	117.4
92	N	80.9	Confident	86.1	Confident	120 Å²	120	69.2 Å²	69.2	64%	0.642	36%	0.364	S	S	*	.	T	Hydrogen-bonded Turn	trans	-129.5	3.6	177.2	-70.1	-22.7	0	0	0	114.2	W90 S94 V95 V96	W90-N92 VanDerWaalsContact C-N 3.25Å; W90-N92 PolarHBondContact O-N 3.43Å; N92-S94 VanDerWaalsContact C-N 3.32Å; N92-S94 PolarHBondContact O-N 3.31Å; N92-V95 PolarHBondContact O-N 3.04Å; N92-V96 PolarHBondContact O-N 3.2Å
93	W	83.4	Confident	86.2	Confident	139 Å²	139	72.4 Å²	72.4	53%	0.527	38%	0.381	S	S	.	.	H	α-helix	trans	-70.8	-27.4	-169.7	-123.5	64.6	0	0	0	113.4	C86 L89 W90 G97	C86-W93 HydrophobicContact CB-CB 4.48Å; C86-W93 HydrophobicContact CB-CE3 4.48Å; L89-W93 HydrophobicContact CD2-CE3 4.07Å; L89-W93 HydrophobicContact CD2-CZ3 4.12Å; W90-W93 HydrophobicContact CB-CB 4.12Å; W90-W93 HydrophobicContact CB-CG 4.31Å; W90-W93 PolarHBondContact O-N 3.11Å; W93-G97 PolarHBondContact O-N 3.43Å
94	S	84.3	Confident	86.4	Confident	36 Å²	36	71.7 Å²	71.7	25%	0.252	38%	0.38	S	S	.	.	H	α-helix	trans	-63.1	-47.2	174	56.1	0	0	0	0	111.3	C86 N92 V96 G97 G98	C86-S94 VanDerWaalsContact CB-CA 3.48Å; N92-S94 VanDerWaalsContact C-N 3.32Å; N92-S94 PolarHBondContact O-N 3.31Å; S94-V96 PolarHBondContact O-N 3.42Å; S94-G97 PolarHBondContact O-N 3.32Å; S94-G98 PolarHBondContact O-N 2.99Å
95	V	85.7	Confident	86.6	Confident	85 Å²	85	71.6 Å²	71.6	52%	0.515	38%	0.377	S	S	.	.	H	α-helix	trans	-61.6	-46.7	179.9	-177.8	0	0	0	0	110.9	N92 G98 W99	N92-V95 PolarHBondContact O-N 3.04Å; V95-G98 PolarHBondContact O-N 2.98Å; V95-W99 PolarHBondContact O-N 3.49Å; V95-W99 VanDerWaalsContact O-N 3.11Å
96	V	88.6	Confident	86.9	Confident	76 Å²	76	72.5 Å²	72.5	46%	0.461	38%	0.383	S	S	.	.	H	α-helix	trans	-62.4	-46.5	178.1	178.1	0	0	0	0	110.9	N92 S94 G98 W99 M100	N92-V96 PolarHBondContact O-N 3.2Å; S94-V96 PolarHBondContact O-N 3.42Å; V96-G98 PolarHBondContact O-N 3.3Å; V96-W99 PolarHBondContact O-N 3.12Å; V96-M100 HydrophobicContact CG1-CG 4.35Å; V96-M100 HydrophobicContact CG1-SD 4Å; V96-M100 VanDerWaalsContact O-CG 3.29Å; V96-M100 WeakPolarHBondContact O-CG 3.45Å; V96-M100 PolarHBondContact O-N 2.88Å
97	G	89.3	Confident	87.3	Confident	3 Å²	3	76 Å²	76	3%	0.031	40%	0.4	C	S	.	.	H	α-helix	trans	-60.5	-43.1	178.6	0	0	0	0	0	112.9	W93 S94 M100 I101	W93-G97 PolarHBondContact O-N 3.43Å; S94-G97 PolarHBondContact O-N 3.32Å; G97-M100 PolarHBondContact O-N 2.89Å; G97-I101 PolarHBondContact O-N 3.17Å; G97-I101 VanDerWaalsContact O-N 3.12Å
98	G	89.9	Confident	87.9	Confident	0 Å²	0	69 Å²	69	0%	0	37%	0.37	C	S	.	.	H	α-helix	trans	-61.2	-45.8	176.4	0	0	0	0	0	113	S94 V95 V96 I101 N102	S94-G98 PolarHBondContact O-N 2.99Å; V95-G98 PolarHBondContact O-N 2.98Å; V96-G98 PolarHBondContact O-N 3.3Å; G98-I101 PolarHBondContact O-N 3.18Å; G98-N102 PolarHBondContact O-N 2.68Å; G98-N102 VanDerWaalsContact O-N 3.1Å
99	W	89.7	Confident	89	Confident	129 Å²	129	65 Å²	65	49%	0.489	33%	0.328	S	S	.	.	H	α-helix	trans	-62.9	-43.3	175.1	-87.4	101	0	0	0	112.7	V95 V96 I101 N102 I103 C303	V95-W99 PolarHBondContact O-N 3.49Å; V95-W99 VanDerWaalsContact O-N 3.11Å; V96-W99 PolarHBondContact O-N 3.12Å; W99-I101 VanDerWaalsContact C-N 3.27Å; W99-I101 PolarHBondContact O-N 2.57Å; W99-N102 PolarHBondContact O-N 3.33Å; W99-I103 WeakPolarHBondContact O-CB 3.38Å; W99-I103 VanDerWaalsContact O-CG1 3.26Å; W99-I103 WeakPolarHBondContact O-CG1 3.28Å; W99-I103 PolarHBondContact O-N 3.37Å; W99-C303 HydrophobicContact CH2-CB 4.16Å; W99-C303 HydrophobicContact CZ3-CB 4.22Å
100	M	92.1	Very high	89.8	Confident	119 Å²	119	62.7 Å²	62.7	59%	0.586	32%	0.316	S	S	*	.	H	α-helix	trans	-58	-40.8	177.9	-74.8	178.4	66.6	0	0	112.1	V96 G97 A104	V96-M100 HydrophobicContact CG1-CG 4.35Å; V96-M100 HydrophobicContact CG1-SD 4Å; V96-M100 VanDerWaalsContact O-CG 3.29Å; V96-M100 WeakPolarHBondContact O-CG 3.45Å; V96-M100 PolarHBondContact O-N 2.88Å; G97-M100 PolarHBondContact O-N 2.89Å; M100-A104 WeakPolarHBondContact O-CB 3.29Å; M100-A104 PolarHBondContact O-N 3.28Å
101	I	93.5	Very high	90.7	Very high	4 Å²	4	54.7 Å²	54.7	2%	0.021	29%	0.287	C	S	.	.	H	α-helix	trans	-69.5	-45.5	178.4	-73.1	-174.7	0	0	0	111.9	Y78 M82 G97 G98 W99 I103 A104 Q105 M362 L366 F370	Y78-I101 HydrophobicContact CD1-CD1 3.95Å; Y78-I101 HydrophobicContact CD1-CG2 3.64Å; Y78-I101 HydrophobicContact CE1-CD1 4.21Å; Y78-I101 HydrophobicContact CE1-CG2 4.41Å; Y78-I101 HydrophobicContact CG-CG2 4.16Å; M82-I101 HydrophobicContact CB-CD1 3.21Å; M82-I101 HydrophobicContact CB-CG1 4.37Å; M82-I101 HydrophobicContact CE-CD1 3.99Å; M82-I101 HydrophobicContact CE-CG1 4.18Å; M82-I101 HydrophobicContact CG-CD1 3.41Å; M82-I101 VanDerWaalsContact CG-CD1 3.41Å; M82-I101 HydrophobicContact CG-CG1 4.2Å; M82-I101 HydrophobicContact SD-CD1 3.93Å; G97-I101 PolarHBondContact O-N 3.17Å; G97-I101 VanDerWaalsContact O-N 3.12Å; G98-I101 PolarHBondContact O-N 3.18Å; W99-I101 VanDerWaalsContact C-N 3.27Å; W99-I101 PolarHBondContact O-N 2.57Å; I101-I103 VanDerWaalsContact C-N 3.26Å; I101-I103 PolarHBondContact O-N 2.71Å; I101-A104 PolarHBondContact O-N 3.28Å; I101-A104 VanDerWaalsContact O-N 3.13Å; I101-Q105 HydrophobicContact CG2-CG 4.33Å; I101-Q105 WeakPolarHBondContact O-CG 3.48Å; I101-Q105 PolarHBondContact O-N 2.85Å; I101-M362 HydrophobicContact CG2-CE 4.24Å; I101-L366 HydrophobicContact CD1-CD1 4.24Å; I101-L366 HydrophobicContact CG1-CD1 4.18Å; I101-F370 HydrophobicContact CD1-CE2 4.36Å; I101-F370 HydrophobicContact CD1-CZ 3.64Å
102	N	93.8	Very high	91.8	Very high	15 Å²	15	49.4 Å²	49.4	8%	0.08	25%	0.252	C	S	.	.	H	α-helix	trans	-60.3	-40.6	177.2	-72.4	-19.8	0	0	0	111.1	Q79 G98 W99 Q105 V106 I299	Q79-N102 PolarHBondContact OE1-ND2 3.38Å; G98-N102 PolarHBondContact O-N 2.68Å; G98-N102 VanDerWaalsContact O-N 3.1Å; W99-N102 PolarHBondContact O-N 3.33Å; N102-Q105 PolarHBondContact O-N 3.17Å; N102-V106 WeakPolarHBondContact O-CB 3.24Å; N102-V106 VanDerWaalsContact O-CG2 3.27Å; N102-V106 WeakPolarHBondContact O-CG2 3.41Å; N102-V106 PolarHBondContact O-N 3.49Å; N102-I299 HydrophobicContact CB-CG2 4.17Å
103	I	94.3	Very high	92.5	Very high	90 Å²	90	43.7 Å²	43.7	46%	0.462	22%	0.222	S	C	.	.	H	α-helix	trans	-61.3	-47.1	174.2	-69.2	166.2	0	0	0	110.6	W99 I101 Q105 V106 I107	W99-I103 WeakPolarHBondContact O-CB 3.38Å; W99-I103 VanDerWaalsContact O-CG1 3.26Å; W99-I103 WeakPolarHBondContact O-CG1 3.28Å; W99-I103 PolarHBondContact O-N 3.37Å; I101-I103 VanDerWaalsContact C-N 3.26Å; I101-I103 PolarHBondContact O-N 2.71Å; I103-Q105 VanDerWaalsContact C-N 3.35Å; I103-Q105 PolarHBondContact O-N 3.22Å; I103-V106 PolarHBondContact O-N 2.98Å; I103-I107 HydrophobicContact CG2-CD1 3.69Å; I103-I107 HydrophobicContact CG2-CG1 4.33Å; I103-I107 VanDerWaalsContact O-CG1 3.28Å; I103-I107 WeakPolarHBondContact O-CG1 3.18Å; I103-I107 PolarHBondContact O-N 3.27Å
104	A	95	Very high	93.1	Very high	21 Å²	21	37 Å²	37	17%	0.174	20%	0.196	C	C	.	.	H	α-helix	trans	-60.7	-42.2	177.8	0	0	0	0	0	112.4	M100 I101 I107 E108 M362	M100-A104 WeakPolarHBondContact O-CB 3.29Å; M100-A104 PolarHBondContact O-N 3.28Å; I101-A104 PolarHBondContact O-N 3.28Å; I101-A104 VanDerWaalsContact O-N 3.13Å; A104-I107 PolarHBondContact O-N 3.41Å; A104-E108 PolarHBondContact O-N 3.38Å; A104-M362 HydrophobicContact CB-SD 3.86Å
105	Q	96.1	Very high	93.6	Very high	12 Å²	12	35.3 Å²	35.3	6%	0.056	18%	0.184	C	C	.	.	H	α-helix	trans	-62	-45.9	174.8	-70.5	-176	-96.6	0	0	111.9	I101 N102 I103 E108 L109 I216 I299 M362	I101-Q105 HydrophobicContact CG2-CG 4.33Å; I101-Q105 WeakPolarHBondContact O-CG 3.48Å; I101-Q105 PolarHBondContact O-N 2.85Å; N102-Q105 PolarHBondContact O-N 3.17Å; I103-Q105 VanDerWaalsContact C-N 3.35Å; I103-Q105 PolarHBondContact O-N 3.22Å; Q105-E108 PolarHBondContact O-N 3.46Å; Q105-L109 WeakPolarHBondContact O-CB 3.25Å; Q105-L109 WeakPolarHBondContact O-CD1 3.29Å; Q105-L109 WeakPolarHBondContact O-CG 3.5Å; Q105-L109 PolarHBondContact O-N 2.82Å; Q105-I216 HydrophobicContact CB-CD1 4.48Å; Q105-I216 HydrophobicContact CB-CG2 4.49Å; Q105-I216 HydrophobicContact CG-CD1 4.41Å; Q105-I216 HydrophobicContact CG-CG1 4.17Å; Q105-I216 HydrophobicContact CG-CG2 4.31Å; Q105-I299 HydrophobicContact CB-CD1 3.8Å; Q105-I299 HydrophobicContact CG-CD1 4.49Å; Q105-M362 HydrophobicContact CG-CE 3.31Å; Q105-M362 HydrophobicContact CG-SD 4.48Å
106	V	96.2	Very high	94.1	Very high	30 Å²	30	31.4 Å²	31.4	18%	0.182	16%	0.16	C	C	.	.	H	α-helix	trans	-64.3	-43	179.3	168.6	0	0	0	0	110.9	N102 I103 L110 T296 I299	N102-V106 WeakPolarHBondContact O-CB 3.24Å; N102-V106 VanDerWaalsContact O-CG2 3.27Å; N102-V106 WeakPolarHBondContact O-CG2 3.41Å; N102-V106 PolarHBondContact O-N 3.49Å; I103-V106 PolarHBondContact O-N 2.98Å; V106-L110 WeakPolarHBondContact O-CB 3.38Å; V106-L110 PolarHBondContact O-N 3.49Å; V106-T296 HydrophobicContact CB-CG2 4.36Å; V106-T296 HydrophobicContact CG1-CG2 4.02Å; V106-T296 HydrophobicContact CG2-CG2 4.22Å; V106-I299 HydrophobicContact CG2-CB 4.34Å; V106-I299 HydrophobicContact CG2-CG2 3.75Å
107	I	95.6	Very high	94.4	Very high	77 Å²	77	27.8 Å²	27.8	40%	0.395	14%	0.139	S	C	.	.	H	α-helix	trans	-59.8	-54.4	175.8	-68.3	168	0	0	0	109.4	I103 A104 L109 L110 M111 T358	I103-I107 HydrophobicContact CG2-CD1 3.69Å; I103-I107 HydrophobicContact CG2-CG1 4.33Å; I103-I107 VanDerWaalsContact O-CG1 3.28Å; I103-I107 WeakPolarHBondContact O-CG1 3.18Å; I103-I107 PolarHBondContact O-N 3.27Å; A104-I107 PolarHBondContact O-N 3.41Å; I107-L109 VanDerWaalsContact C-N 3.31Å; I107-L109 PolarHBondContact O-N 3.28Å; I107-L110 PolarHBondContact O-N 2.9Å; I107-M111 HydrophobicContact CG2-CG 4.17Å; I107-M111 WeakPolarHBondContact O-CG 3.34Å; I107-M111 PolarHBondContact O-N 3.42Å; I107-T358 HydrophobicContact CB-CG2 4.13Å; I107-T358 HydrophobicContact CG2-CG2 3.75Å
108	E	95.8	Very high	94.6	Very high	4 Å²	4	28.1 Å²	28.1	2%	0.019	14%	0.139	C	C	.	.	H	α-helix	trans	-55.5	-46.9	-177.5	-171.1	163	146.7	0	0	112.4	A104 Q105 M111 T112 F210 T213 I216 T354 T358 G359	A104-E108 PolarHBondContact O-N 3.38Å; Q105-E108 PolarHBondContact O-N 3.46Å; E108-M111 PolarHBondContact O-N 3.31Å; E108-T112 WeakPolarHBondContact O-CB 3.31Å; E108-T112 PolarHBondContact O-N 3.47Å; E108-T112 PolarHBondContact O-OG1 2.79Å; E108-F210 HydrophobicContact CG-CE2 4.42Å; E108-T213 VanDerWaalsContact OE1-CB 3.26Å; E108-T213 WeakPolarHBondContact OE1-CB 3.29Å; E108-T213 PolarHBondContact OE1-OG1 3.47Å; E108-I216 HydrophobicContact CB-CD1 3.79Å; E108-I216 HydrophobicContact CG-CD1 3.88Å; E108-T354 HydrophobicContact CG-CG2 4.15Å; E108-T358 HydrophobicContact CB-CG2 4.31Å; E108-T358 VanDerWaalsContact CB-OG1 3.3Å; E108-T358 WeakPolarHBondContact CB-OG1 3.15Å; E108-T358 WeakPolarHBondContact CG-OG1 3.44Å; E108-T358 VanDerWaalsContact OE2-CB 3.3Å; E108-T358 WeakPolarHBondContact OE2-CB 3.4Å; E108-T358 PolarHBondContact OE2-OG1 3.24Å; E108-G359 PolarHBondContact OE2-N 2.95Å
109	L	96.6	Very high	94.7	Very high	3 Å²	3	28.1 Å²	28.1	2%	0.016	14%	0.14	C	C	.	.	H	α-helix	trans	-74.1	-32.2	-177.9	-61.4	167.5	0	0	0	112.4	Q105 I107 T112 C113 I216 F217 P292 A295 T296 I299	Q105-L109 WeakPolarHBondContact O-CB 3.25Å; Q105-L109 WeakPolarHBondContact O-CD1 3.29Å; Q105-L109 WeakPolarHBondContact O-CG 3.5Å; Q105-L109 PolarHBondContact O-N 2.82Å; I107-L109 VanDerWaalsContact C-N 3.31Å; I107-L109 PolarHBondContact O-N 3.28Å; L109-T112 WeakPolarHBondContact O-CB 3.34Å; L109-T112 PolarHBondContact O-N 3.11Å; L109-C113 PolarHBondContact O-N 2.91Å; L109-C113 PolarHBondContact O-SG 3.02Å; L109-I216 HydrophobicContact CD1-CG2 3.83Å; L109-I216 HydrophobicContact CD2-CD1 4.28Å; L109-I216 HydrophobicContact CD2-CG2 4.18Å; L109-I216 HydrophobicContact CG-CD1 4.13Å; L109-I216 HydrophobicContact CG-CG2 4.22Å; L109-F217 HydrophobicContact CD2-CE1 3.96Å; L109-F217 HydrophobicContact CD2-CE2 4.27Å; L109-F217 HydrophobicContact CD2-CZ 3.49Å; L109-F217 VanDerWaalsContact CD2-CZ 3.49Å; L109-P292 HydrophobicContact CD2-CB 3.92Å; L109-A295 HydrophobicContact CD1-CB 3.88Å; L109-A295 HydrophobicContact CD2-CB 4.48Å; L109-T296 HydrophobicContact CB-CG2 4.34Å; L109-T296 WeakPolarHBondContact CB-OG1 3.27Å; L109-T296 WeakPolarHBondContact CD1-OG1 3.48Å; L109-I299 HydrophobicContact CD1-CD1 4.03Å
110	L	96.4	Very high	94.9	Very high	37 Å²	37	22 Å²	22	19%	0.194	12%	0.117	C	C	.	.	H	α-helix	trans	-63.8	-44.9	171.2	178.4	71.3	0	0	0	110.9	V106 I107 T112 C113 T114 L333	V106-L110 WeakPolarHBondContact O-CB 3.38Å; V106-L110 PolarHBondContact O-N 3.49Å; I107-L110 PolarHBondContact O-N 2.9Å; L110-T112 VanDerWaalsContact C-N 3.3Å; L110-T112 PolarHBondContact O-N 3.41Å; L110-C113 PolarHBondContact O-N 3.46Å; L110-T114 WeakPolarHBondContact O-CB 3.34Å; L110-T114 PolarHBondContact O-N 2.78Å; L110-T114 PolarHBondContact O-OG1 2.98Å; L110-L333 HydrophobicContact CD1-CD1 3.74Å
111	M	95.1	Very high	95	Very high	26 Å²	26	16.6 Å²	16.6	13%	0.128	9%	0.09	C	C	.	.	H	α-helix	trans	-61.7	-41.1	174.3	-61.1	-44.8	-75.8	0	0	111	I107 E108 T114 L115 L340 L350 T354	I107-M111 HydrophobicContact CG2-CG 4.17Å; I107-M111 WeakPolarHBondContact O-CG 3.34Å; I107-M111 PolarHBondContact O-N 3.42Å; E108-M111 PolarHBondContact O-N 3.31Å; M111-T114 WeakPolarHBondContact O-CB 3.33Å; M111-T114 PolarHBondContact O-N 3.2Å; M111-L115 WeakPolarHBondContact O-CG 3.31Å; M111-L115 PolarHBondContact O-N 2.88Å; M111-L340 HydrophobicContact CE-CD2 4.1Å; M111-L340 HydrophobicContact SD-CD2 3.61Å; M111-L350 HydrophobicContact CE-CD1 3.06Å; M111-L350 HydrophobicContact CE-CD2 4.41Å; M111-L350 HydrophobicContact CE-CG 3.9Å; M111-T354 HydrophobicContact CB-CG2 3.68Å; M111-T354 WeakPolarHBondContact CB-OG1 3.33Å; M111-T354 HydrophobicContact CG-CG2 4.18Å
112	T	95.6	Very high	94.9	Very high	11 Å²	11	18 Å²	18	7%	0.067	10%	0.1	C	C	.	.	H	α-helix	trans	-59.4	-47.7	174.7	-56.2	0	0	0	0	111.4	F20 E108 L109 L110 T114 L115 Y116 F210 P292	F20-T112 HydrophobicContact CE2-CG2 3.91Å; F20-T112 HydrophobicContact CZ-CG2 3.6Å; E108-T112 WeakPolarHBondContact O-CB 3.31Å; E108-T112 PolarHBondContact O-N 3.47Å; E108-T112 PolarHBondContact O-OG1 2.79Å; L109-T112 WeakPolarHBondContact O-CB 3.34Å; L109-T112 PolarHBondContact O-N 3.11Å; L110-T112 VanDerWaalsContact C-N 3.3Å; L110-T112 PolarHBondContact O-N 3.41Å; T112-T114 VanDerWaalsContact C-N 3.31Å; T112-T114 PolarHBondContact O-N 3.29Å; T112-L115 PolarHBondContact O-N 3.33Å; T112-Y116 HydrophobicContact CG2-CD2 4.13Å; T112-Y116 HydrophobicContact CG2-CE2 3.76Å; T112-Y116 WeakPolarHBondContact O-CD2 3.38Å; T112-Y116 PolarHBondContact O-N 2.94Å; T112-Y116 VanDerWaalsContact O-N 3.13Å; T112-F210 HydrophobicContact CG2-CZ 4.29Å; T112-F210 WeakPolarHBondContact OG1-CZ 3.37Å; T112-P292 HydrophobicContact CG2-CB 3.8Å; T112-P292 HydrophobicContact CG2-CG 3.85Å
113	C	96.3	Very high	94.8	Very high	0 Å²	0	17.3 Å²	17.3	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-61.1	-40.9	175.3	-67.9	0	0	0	0	111.9	L109 L110 Y116 L117 Y289	L109-C113 PolarHBondContact O-N 2.91Å; L109-C113 PolarHBondContact O-SG 3.02Å; L110-C113 PolarHBondContact O-N 3.46Å; C113-Y116 PolarHBondContact O-N 2.92Å; C113-L117 PolarHBondContact O-N 3.44Å; C113-L117 VanDerWaalsContact O-N 3.09Å; C113-Y289 HydrophobicContact CB-CD2 4.38Å; C113-Y289 HydrophobicContact CB-CE2 3.57Å; C113-Y289 WeakPolarHBondContact O-CE2 3.47Å
114	T	95.8	Very high	94.7	Very high	0 Å²	0	13.4 Å²	13.4	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-61.9	-44.5	177	-58.1	0	0	0	0	111.5	L110 M111 T112 Y116 L117 L118 L340 L350	L110-T114 WeakPolarHBondContact O-CB 3.34Å; L110-T114 PolarHBondContact O-N 2.78Å; L110-T114 PolarHBondContact O-OG1 2.98Å; M111-T114 WeakPolarHBondContact O-CB 3.33Å; M111-T114 PolarHBondContact O-N 3.2Å; T112-T114 VanDerWaalsContact C-N 3.31Å; T112-T114 PolarHBondContact O-N 3.29Å; T114-Y116 VanDerWaalsContact C-N 3.34Å; T114-Y116 PolarHBondContact O-N 3.01Å; T114-L117 PolarHBondContact O-N 2.95Å; T114-L118 WeakPolarHBondContact O-CB 3.13Å; T114-L118 PolarHBondContact O-N 3.13Å; T114-L340 HydrophobicContact CG2-CB 3.83Å; T114-L340 HydrophobicContact CG2-CD2 4.03Å; T114-L340 HydrophobicContact CG2-CG 3.79Å; T114-L350 HydrophobicContact CG2-CD2 3.9Å
115	L	94.7	Very high	94.5	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-60.4	-42.2	176.1	-76.2	163.4	0	0	0	111.9	F20 M111 T112 L118 V119 F210 F347 L350 M351	F20-L115 HydrophobicContact CD1-CD1 4.46Å; F20-L115 HydrophobicContact CE1-CB 3.75Å; F20-L115 HydrophobicContact CE1-CD1 3.94Å; F20-L115 HydrophobicContact CE1-CG 4.44Å; F20-L115 HydrophobicContact CZ-CB 4.48Å; M111-L115 WeakPolarHBondContact O-CG 3.31Å; M111-L115 PolarHBondContact O-N 2.88Å; T112-L115 PolarHBondContact O-N 3.33Å; L115-L118 PolarHBondContact O-N 3.4Å; L115-V119 WeakPolarHBondContact O-CG2 3.21Å; L115-V119 PolarHBondContact O-N 2.93Å; L115-F210 HydrophobicContact CD1-CD1 4.36Å; L115-F210 HydrophobicContact CD1-CE1 3.46Å; L115-F210 VanDerWaalsContact CD1-CE1 3.46Å; L115-F210 HydrophobicContact CD1-CZ 3.64Å; L115-F347 HydrophobicContact CB-CE2 4.32Å; L115-F347 HydrophobicContact CD2-CD2 3.49Å; L115-F347 VanDerWaalsContact CD2-CD2 3.49Å; L115-F347 HydrophobicContact CD2-CE2 3.63Å; L115-L350 HydrophobicContact CD2-CB 3.77Å; L115-L350 HydrophobicContact CD2-CD2 3.66Å; L115-L350 HydrophobicContact CD2-CG 3.88Å; L115-L350 HydrophobicContact CG-CD2 3.74Å; L115-L350 HydrophobicContact CG-CG 4.11Å; L115-M351 HydrophobicContact CD1-CB 4.49Å; L115-M351 HydrophobicContact CD2-CB 4.37Å
116	Y	95.3	Very high	94.2	Very high	3 Å²	3	15.4 Å²	15.4	1%	0.012	9%	0.086	C	C	.	.	H	α-helix	trans	-61.9	-42.9	175.5	-82.9	-64.5	0	0	0	112.3	G18 I19 F20 T112 C113 T114 S120 A285 S288 Y289 P292	G18-Y116 WeakPolarHBondContact CA-OH 3.33Å; I19-Y116 HydrophobicContact CB-CD1 4.01Å; I19-Y116 HydrophobicContact CB-CE1 3.6Å; I19-Y116 HydrophobicContact CG2-CD1 3.55Å; I19-Y116 HydrophobicContact CG2-CE1 3.39Å; I19-Y116 HydrophobicContact CG2-CG 4.39Å; I19-Y116 PolarHBondContact N-OH 2.76Å; F20-Y116 HydrophobicContact CE1-CE2 4.43Å; F20-Y116 HydrophobicContact CE2-CE2 4.13Å; F20-Y116 HydrophobicContact CZ-CD2 4.15Å; F20-Y116 HydrophobicContact CZ-CE1 4.46Å; F20-Y116 AromaticContact CZ-CE2 3.56Å; F20-Y116 HydrophobicContact CZ-CE2 3.56Å; F20-Y116 AromaticContact CZ-CZ 3.7Å; T112-Y116 HydrophobicContact CG2-CD2 4.13Å; T112-Y116 HydrophobicContact CG2-CE2 3.76Å; T112-Y116 WeakPolarHBondContact O-CD2 3.38Å; T112-Y116 PolarHBondContact O-N 2.94Å; T112-Y116 VanDerWaalsContact O-N 3.13Å; C113-Y116 PolarHBondContact O-N 2.92Å; T114-Y116 VanDerWaalsContact C-N 3.34Å; T114-Y116 PolarHBondContact O-N 3.01Å; Y116-S120 VanDerWaalsContact O-CB 3.22Å; Y116-S120 WeakPolarHBondContact O-CB 3.28Å; Y116-S120 PolarHBondContact O-N 3.47Å; Y116-S120 PolarHBondContact O-OG 3.1Å; Y116-A285 HydrophobicContact CD1-CB 4.04Å; Y116-A285 WeakPolarHBondContact CD1-O 3.46Å; Y116-S288 VanDerWaalsContact CZ-OG 3.32Å; Y116-S288 PolarHBondContact OH-OG 3.3Å; Y116-Y289 HydrophobicContact CD2-CD2 4.43Å; Y116-Y289 HydrophobicContact CG-CD2 4.3Å; Y116-P292 HydrophobicContact CD2-CG 4.22Å; Y116-P292 HydrophobicContact CE2-CG 3.96Å
117	L	95.2	Very high	93.9	Very high	0 Å²	0	15.1 Å²	15.1	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-65.2	-44.4	176.5	-83.9	161	0	0	0	112.4	C113 T114 S120 T121 L146 Y289 S337 Y338	C113-L117 PolarHBondContact O-N 3.44Å; C113-L117 VanDerWaalsContact O-N 3.09Å; T114-L117 PolarHBondContact O-N 2.95Å; L117-S120 PolarHBondContact O-N 3.3Å; L117-T121 WeakPolarHBondContact O-CB 3.48Å; L117-T121 PolarHBondContact O-N 3.1Å; L117-T121 PolarHBondContact O-OG1 3.34Å; L117-L146 HydrophobicContact CD2-CD1 3.56Å; L117-L146 HydrophobicContact CG-CD1 3.94Å; L117-Y289 HydrophobicContact CD1-CE2 4.2Å; L117-Y289 HydrophobicContact CG-CE2 4.22Å; L117-S337 VanDerWaalsContact CD1-OG 3.31Å; L117-S337 WeakPolarHBondContact CD1-OG 3.37Å; L117-Y338 HydrophobicContact CD2-CD2 4.43Å
118	L	93.7	Very high	93.5	Very high	9 Å²	9	14.4 Å²	14.4	5%	0.047	8%	0.082	C	C	.	.	H	α-helix	trans	-58.8	-50.3	177.8	177.8	63	0	0	0	111.1	T114 L115 T121 S122 F347	T114-L118 WeakPolarHBondContact O-CB 3.13Å; T114-L118 PolarHBondContact O-N 3.13Å; L115-L118 PolarHBondContact O-N 3.4Å; L118-T121 WeakPolarHBondContact O-CB 3.4Å; L118-T121 PolarHBondContact O-N 2.92Å; L118-S122 PolarHBondContact O-N 3.46Å; L118-F347 HydrophobicContact CD2-CB 4.31Å
119	V	92.8	Very high	92.9	Very high	1 Å²	1	17.9 Å²	17.9	1%	0.006	11%	0.107	C	C	.	.	H	α-helix	trans	-69.5	-38.3	179.5	174.7	0	0	0	0	112	I19 L115 T121 S122 L123 F347	I19-V119 HydrophobicContact CD1-CG1 4.37Å; I19-V119 HydrophobicContact CG1-CB 4.36Å; I19-V119 HydrophobicContact CG1-CG1 3.62Å; L115-V119 WeakPolarHBondContact O-CG2 3.21Å; L115-V119 PolarHBondContact O-N 2.93Å; V119-T121 PolarHBondContact O-N 2.85Å; V119-S122 PolarHBondContact O-N 3.43Å; V119-S122 PolarHBondContact O-OG 2.96Å; V119-L123 HydrophobicContact CG1-CD1 3.53Å; V119-L123 HydrophobicContact CG1-CG 3.84Å; V119-L123 WeakPolarHBondContact O-CB 3.23Å; V119-L123 VanDerWaalsContact O-CG 3.23Å; V119-L123 WeakPolarHBondContact O-CG 3.44Å; V119-L123 PolarHBondContact O-N 2.99Å; V119-F347 HydrophobicContact CG2-CD2 3.27Å; V119-F347 HydrophobicContact CG2-CE1 4.46Å; V119-F347 HydrophobicContact CG2-CE2 3.12Å; V119-F347 HydrophobicContact CG2-CG 4.03Å; V119-F347 HydrophobicContact CG2-CZ 3.75Å
120	S	94.1	Very high	92.4	Very high	1 Å²	1	22.7 Å²	22.7	1%	0.007	15%	0.147	C	C	.	.	H	α-helix	trans	-60.6	-40.3	176.4	-61.2	0	0	0	0	111	Y116 L117 L124 L282	Y116-S120 VanDerWaalsContact O-CB 3.22Å; Y116-S120 WeakPolarHBondContact O-CB 3.28Å; Y116-S120 PolarHBondContact O-N 3.47Å; Y116-S120 PolarHBondContact O-OG 3.1Å; L117-S120 PolarHBondContact O-N 3.3Å; S120-L124 WeakPolarHBondContact O-CB 3.4Å; S120-L124 PolarHBondContact O-N 2.85Å; S120-L282 WeakPolarHBondContact O-CD1 3.3Å
121	T	92.9	Very high	91.9	Very high	5 Å²	5	26.5 Å²	26.5	3%	0.031	17%	0.172	C	C	.	.	H	α-helix	trans	-62.5	-46.8	176.8	-59.6	0	0	0	0	112	L117 L118 V119 C125 R135 C138 S139	L117-T121 WeakPolarHBondContact O-CB 3.48Å; L117-T121 PolarHBondContact O-N 3.1Å; L117-T121 PolarHBondContact O-OG1 3.34Å; L118-T121 WeakPolarHBondContact O-CB 3.4Å; L118-T121 PolarHBondContact O-N 2.92Å; V119-T121 PolarHBondContact O-N 2.85Å; T121-C125 WeakPolarHBondContact O-CB 3.49Å; T121-C125 PolarHBondContact O-N 3.25Å; T121-C125 VanDerWaalsContact O-N 3.08Å; T121-R135 HydrophobicContact CG2-CG 3.97Å; T121-C138 HydrophobicContact CG2-CB 4.1Å; T121-S139 WeakPolarHBondContact OG1-CA 3.35Å
122	S	90.8	Very high	91.5	Very high	33 Å²	33	29 Å²	29	23%	0.231	20%	0.197	C	C	.	.	H	α-helix	trans	-65.7	-51.4	179.5	62.9	0	0	0	0	111.5	L118 V119 L124 C125 D126	L118-S122 PolarHBondContact O-N 3.46Å; V119-S122 PolarHBondContact O-N 3.43Å; V119-S122 PolarHBondContact O-OG 2.96Å; S122-L124 PolarHBondContact O-N 3.32Å; S122-C125 PolarHBondContact O-N 2.94Å; S122-C125 VanDerWaalsContact O-N 3.14Å; S122-D126 VanDerWaalsContact O-CG 3.31Å; S122-D126 PolarHBondContact O-N 3.3Å
123	L	92.4	Very high	91.2	Very high	0 Å²	0	30 Å²	30	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-57	-39.8	179.8	-68.6	176.3	0	0	0	112	I19 V119 S127 N278 L281 L282	I19-L123 HydrophobicContact CD1-CD1 4.46Å; V119-L123 HydrophobicContact CG1-CD1 3.53Å; V119-L123 HydrophobicContact CG1-CG 3.84Å; V119-L123 WeakPolarHBondContact O-CB 3.23Å; V119-L123 VanDerWaalsContact O-CG 3.23Å; V119-L123 WeakPolarHBondContact O-CG 3.44Å; V119-L123 PolarHBondContact O-N 2.99Å; L123-S127 WeakPolarHBondContact O-CB 3.33Å; L123-S127 PolarHBondContact O-N 2.97Å; L123-S127 PolarHBondContact O-OG 3.34Å; L123-N278 HydrophobicContact CB-CB 4.46Å; L123-N278 HydrophobicContact CD2-CB 4.08Å; L123-L281 HydrophobicContact CD1-CB 3.69Å; L123-L281 HydrophobicContact CD2-CB 4.45Å; L123-L282 HydrophobicContact CB-CB 4.26Å; L123-L282 HydrophobicContact CD1-CB 4.5Å
124	L	93.1	Very high	90.9	Very high	9 Å²	9	34 Å²	34	5%	0.047	23%	0.229	C	C	.	.	H	α-helix	trans	-69.8	-43.9	179.2	178.9	57.5	0	0	0	112.4	S120 S122 D126 S127 L128 C138 M141 L282	S120-L124 WeakPolarHBondContact O-CB 3.4Å; S120-L124 PolarHBondContact O-N 2.85Å; S122-L124 PolarHBondContact O-N 3.32Å; L124-D126 VanDerWaalsContact C-N 3.33Å; L124-D126 PolarHBondContact O-N 3.35Å; L124-S127 PolarHBondContact O-N 3Å; L124-L128 HydrophobicContact CD1-CD1 3.86Å; L124-L128 HydrophobicContact CD1-CG 4.24Å; L124-L128 HydrophobicContact CG-CD1 4.35Å; L124-L128 WeakPolarHBondContact O-CG 3.3Å; L124-L128 PolarHBondContact O-N 3.48Å; L124-L128 VanDerWaalsContact O-N 3.08Å; L124-C138 HydrophobicContact CB-CB 4.41Å; L124-C138 HydrophobicContact CD2-CB 4.15Å; L124-C138 WeakPolarHBondContact CD2-O 3.41Å; L124-C138 HydrophobicContact CG-CB 4.23Å; L124-M141 HydrophobicContact CD1-CE 3.52Å; L124-M141 HydrophobicContact CD2-CB 3.94Å; L124-M141 HydrophobicContact CD2-CE 3.37Å; L124-M141 HydrophobicContact CD2-CG 4.03Å; L124-M141 HydrophobicContact CG-CE 3.77Å; L124-L282 HydrophobicContact CB-CD1 4.41Å; L124-L282 HydrophobicContact CB-CD2 3.88Å; L124-L282 HydrophobicContact CD1-CD2 3.71Å; L124-L282 HydrophobicContact CG-CD2 4.27Å
125	C	91.1	Very high	90.6	Very high	24 Å²	24	40.9 Å²	40.9	16%	0.162	26%	0.255	C	S	.	.	H	α-helix	trans	-60.7	-43.4	175.5	-87.9	0	0	0	0	111.9	T121 S122 L128 S129 C138	T121-C125 WeakPolarHBondContact O-CB 3.49Å; T121-C125 PolarHBondContact O-N 3.25Å; T121-C125 VanDerWaalsContact O-N 3.08Å; S122-C125 PolarHBondContact O-N 2.94Å; S122-C125 VanDerWaalsContact O-N 3.14Å; C125-L128 CarbonylContact O-C 3.37Å; C125-L128 PolarHBondContact O-N 3.36Å; C125-S129 PolarHBondContact O-N 3.02Å; C125-S129 VanDerWaalsContact O-N 3.1Å; C125-C138 WeakPolarHBondContact CA-SG 3.27Å; C125-C138 HydrophobicContact CB-CB 4.12Å; C125-C138 WeakPolarHBondContact CB-SG 3.4Å; C125-C138 WeakPolarHBondContact SG-CB 3.41Å; C125-C138 CovalentContact SG-SG 2.05Å; C125-C138 PolarHBondContact SG-SG 2.9Å
126	D	88.3	Confident	90.5	Very high	51 Å²	51	44.9 Å²	44.9	27%	0.273	28%	0.283	S	S	.	.	H	α-helix	trans	-67.9	-37.6	178.7	-64.8	-31.7	0	0	0	112.2	S122 L124 L128 S129 N278	S122-D126 VanDerWaalsContact O-CG 3.31Å; S122-D126 PolarHBondContact O-N 3.3Å; L124-D126 VanDerWaalsContact C-N 3.33Å; L124-D126 PolarHBondContact O-N 3.35Å; D126-L128 PolarHBondContact O-N 2.59Å; D126-S129 VanDerWaalsContact O-CB 3.23Å; D126-S129 WeakPolarHBondContact O-CB 3.43Å; D126-S129 PolarHBondContact O-N 3.2Å; D126-S129 PolarHBondContact O-OG 3.48Å; D126-N278 VanDerWaalsContact CB-ND2 3.28Å; D126-N278 WeakPolarHBondContact CB-ND2 3.3Å
127	S	89.6	Confident	90.4	Very high	23 Å²	23	46.8 Å²	46.8	16%	0.161	30%	0.3	C	S	.	.	H	α-helix	trans	-63.1	-31.5	175.2	-59.2	0	0	0	0	112.2	L123 L124 N278 L279	L123-S127 WeakPolarHBondContact O-CB 3.33Å; L123-S127 PolarHBondContact O-N 2.97Å; L123-S127 PolarHBondContact O-OG 3.34Å; L124-S127 PolarHBondContact O-N 3Å; S127-N278 WeakPolarHBondContact OG-CB 2.85Å; S127-L279 PolarHBondContact OG-N 2.76Å
128	L	88.8	Confident	90.3	Very high	63 Å²	63	46.9 Å²	46.9	33%	0.33	30%	0.3	S	S	.	.	T	Hydrogen-bonded Turn	trans	-100.4	18.5	178.8	-62.3	178.7	0	0	0	112.8	L124 C125 D126 A130 V131 A132 P133 M141	L124-L128 HydrophobicContact CD1-CD1 3.86Å; L124-L128 HydrophobicContact CD1-CG 4.24Å; L124-L128 HydrophobicContact CG-CD1 4.35Å; L124-L128 WeakPolarHBondContact O-CG 3.3Å; L124-L128 PolarHBondContact O-N 3.48Å; L124-L128 VanDerWaalsContact O-N 3.08Å; C125-L128 CarbonylContact O-C 3.37Å; C125-L128 PolarHBondContact O-N 3.36Å; D126-L128 PolarHBondContact O-N 2.59Å; L128-A130 PolarHBondContact O-N 2.91Å; L128-V131 PolarHBondContact O-N 3.2Å; L128-A132 PolarHBondContact O-N 3.46Å; L128-A132 VanDerWaalsContact O-N 3.13Å; L128-P133 HydrophobicContact CB-CG 3.81Å; L128-P133 HydrophobicContact CD1-CG 4.32Å; L128-P133 VanDerWaalsContact O-CD 3.22Å; L128-P133 WeakPolarHBondContact O-CD 3.48Å; L128-M141 HydrophobicContact CD1-CE 3.78Å
129	S	83.1	Confident	90.3	Very high	76 Å²	76	46.6 Å²	46.6	53%	0.531	30%	0.299	S	S	.	.	T	Hydrogen-bonded Turn	trans	-52.9	-30.7	-177.8	46.7	0	0	0	0	114	C125 D126 V131 A132	C125-S129 PolarHBondContact O-N 3.02Å; C125-S129 VanDerWaalsContact O-N 3.1Å; D126-S129 VanDerWaalsContact O-CB 3.23Å; D126-S129 WeakPolarHBondContact O-CB 3.43Å; D126-S129 PolarHBondContact O-N 3.2Å; D126-S129 PolarHBondContact O-OG 3.48Å; S129-V131 VanDerWaalsContact C-N 3.27Å; S129-V131 PolarHBondContact O-N 3.38Å; S129-A132 PolarHBondContact O-N 3.36Å
130	A	84.8	Confident	90.4	Very high	105 Å²	105	50.9 Å²	50.9	87%	0.868	32%	0.321	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.8	-30.8	174.8	0	0	0	0	0	113.8	L128	L128-A130 PolarHBondContact O-N 2.91Å
131	V	87.1	Confident	90.4	Very high	116 Å²	116	54.4 Å²	54.4	70%	0.703	34%	0.338	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.5	-17.6	177.4	-177.2	0	0	0	0	111.2	L128 S129	L128-V131 PolarHBondContact O-N 3.2Å; S129-V131 VanDerWaalsContact C-N 3.27Å; S129-V131 PolarHBondContact O-N 3.38Å
132	A	86.8	Confident	90.4	Very high	79 Å²	79	54.1 Å²	54.1	65%	0.653	34%	0.337	S	S	*	.			trans	48.3	52.7	-177	0	0	0	0	0	113.7	L128 S129	L128-A132 PolarHBondContact O-N 3.46Å; L128-A132 VanDerWaalsContact O-N 3.13Å; S129-A132 PolarHBondContact O-N 3.36Å
133	P	88.7	Confident	90.6	Very high	32 Å²	32	53.6 Å²	53.6	21%	0.208	33%	0.332	C	S	.	.			trans	-63.9	147.5	179	29.4	-35.2	0	0	0	111	L128	L128-P133 HydrophobicContact CB-CG 3.81Å; L128-P133 HydrophobicContact CD1-CG 4.32Å; L128-P133 VanDerWaalsContact O-CD 3.22Å; L128-P133 WeakPolarHBondContact O-CD 3.48Å
134	P	91.1	Very high	90.7	Very high	83 Å²	83	58.3 Å²	58.3	54%	0.539	35%	0.354	S	S	.	.			trans	-62.6	144.8	173.8	27.2	-33.4	0	0	0	110	S136 A137 C138	P134-S136 PolarHBondContact O-N 3.09Å; P134-S136 VanDerWaalsContact O-N 3.08Å; P134-A137 HydrophobicContact CG-CB 3.91Å; P134-A137 WeakPolarHBondContact O-CB 3.34Å; P134-A137 PolarHBondContact O-N 3.25Å; P134-C138 PolarHBondContact O-N 2.94Å
135	R	89.2	Confident	90.8	Very high	145 Å²	145	63.4 Å²	63.4	55%	0.547	38%	0.376	S	S	.	.	H	α-helix	trans	-54.3	-33.8	-178.2	-172.8	172.5	176.9	160	-3	113.3	T121 A137 C138 S139	T121-R135 HydrophobicContact CG2-CG 3.97Å; R135-A137 VanDerWaalsContact C-N 3.31Å; R135-A137 PolarHBondContact O-N 3.29Å; R135-C138 PolarHBondContact O-N 2.95Å; R135-S139 VanDerWaalsContact O-CB 3.31Å; R135-S139 WeakPolarHBondContact O-CB 3.5Å; R135-S139 PolarHBondContact O-N 3.43Å
136	S	90.9	Very high	91	Very high	84 Å²	84	62.3 Å²	62.3	59%	0.587	37%	0.369	S	S	*	.	H	α-helix	trans	-61.8	-35.2	175.1	54.8	0	0	0	0	113.1	P134 L140	P134-S136 PolarHBondContact O-N 3.09Å; P134-S136 VanDerWaalsContact O-N 3.08Å; S136-L140 WeakPolarHBondContact O-CB 3.45Å; S136-L140 PolarHBondContact O-N 3.5Å
137	A	93.5	Very high	91.3	Very high	44 Å²	44	63.6 Å²	63.6	36%	0.364	38%	0.376	S	S	.	.	H	α-helix	trans	-70.8	-43.7	176.4	0	0	0	0	0	111.8	P134 R135 S139 L140 M141	P134-A137 HydrophobicContact CG-CB 3.91Å; P134-A137 WeakPolarHBondContact O-CB 3.34Å; P134-A137 PolarHBondContact O-N 3.25Å; R135-A137 VanDerWaalsContact C-N 3.31Å; R135-A137 PolarHBondContact O-N 3.29Å; A137-S139 VanDerWaalsContact C-N 3.28Å; A137-S139 PolarHBondContact O-N 3.37Å; A137-L140 PolarHBondContact O-N 3.46Å; A137-M141 WeakPolarHBondContact O-CB 3.33Å; A137-M141 PolarHBondContact O-N 2.9Å
138	C	93.4	Very high	91.4	Very high	2 Å²	2	66.5 Å²	66.5	1%	0.014	39%	0.394	C	S	.	.	H	α-helix	trans	-60.4	-41	173.7	-52	0	0	0	0	111.5	T121 L124 C125 P134 R135 M141 S142	T121-C138 HydrophobicContact CG2-CB 4.1Å; L124-C138 HydrophobicContact CB-CB 4.41Å; L124-C138 HydrophobicContact CD2-CB 4.15Å; L124-C138 WeakPolarHBondContact CD2-O 3.41Å; L124-C138 HydrophobicContact CG-CB 4.23Å; C125-C138 WeakPolarHBondContact CA-SG 3.27Å; C125-C138 HydrophobicContact CB-CB 4.12Å; C125-C138 WeakPolarHBondContact CB-SG 3.4Å; C125-C138 WeakPolarHBondContact SG-CB 3.41Å; C125-C138 CovalentContact SG-SG 2.05Å; C125-C138 PolarHBondContact SG-SG 2.9Å; P134-C138 PolarHBondContact O-N 2.94Å; R135-C138 PolarHBondContact O-N 2.95Å; C138-M141 PolarHBondContact O-N 2.74Å; C138-S142 WeakPolarHBondContact O-CB 3.41Å; C138-S142 PolarHBondContact O-N 3.49Å; C138-S142 PolarHBondContact O-OG 3.16Å
139	S	93.6	Very high	91.5	Very high	2 Å²	2	63.9 Å²	63.9	1%	0.014	38%	0.381	C	S	.	.	H	α-helix	trans	-63	-48.9	179	-174.4	0	0	0	0	111.3	T121 R135 A137 M141 S142 L143 Y338 L342	T121-S139 WeakPolarHBondContact OG1-CA 3.35Å; R135-S139 VanDerWaalsContact O-CB 3.31Å; R135-S139 WeakPolarHBondContact O-CB 3.5Å; R135-S139 PolarHBondContact O-N 3.43Å; A137-S139 VanDerWaalsContact C-N 3.28Å; A137-S139 PolarHBondContact O-N 3.37Å; S139-M141 VanDerWaalsContact C-N 3.33Å; S139-M141 PolarHBondContact O-N 2.77Å; S139-S142 PolarHBondContact O-N 3.37Å; S139-L143 PolarHBondContact O-N 2.91Å; S139-Y338 WeakPolarHBondContact OG-CE2 3.4Å; S139-Y338 PolarHBondContact OG-OH 3.43Å; S139-L342 WeakPolarHBondContact OG-CD2 3.37Å
140	L	94.8	Very high	92	Very high	92 Å²	92	61.4 Å²	61.4	48%	0.482	36%	0.361	S	S	.	.	H	α-helix	trans	-63.2	-39.4	177	-175.7	63.3	0	0	0	111.9	S136 A137 L143 M144	S136-L140 WeakPolarHBondContact O-CB 3.45Å; S136-L140 PolarHBondContact O-N 3.5Å; A137-L140 PolarHBondContact O-N 3.46Å; L140-L143 HydrophobicContact CD1-CD2 4.31Å; L140-L143 WeakPolarHBondContact O-CB 3.22Å; L140-L143 PolarHBondContact O-N 2.74Å; L140-M144 VanDerWaalsContact O-CG 3.32Å; L140-M144 WeakPolarHBondContact O-CG 3.46Å; L140-M144 PolarHBondContact O-N 3.49Å
141	M	94.2	Very high	92.2	Very high	74 Å²	74	61.9 Å²	61.9	37%	0.365	35%	0.349	S	S	.	.	H	α-helix	trans	-66.9	-39.5	177.5	-175	155.8	72.4	0	0	111.9	L124 L128 A137 C138 S139 L143 M144 F145	L124-M141 HydrophobicContact CD1-CE 3.52Å; L124-M141 HydrophobicContact CD2-CB 3.94Å; L124-M141 HydrophobicContact CD2-CE 3.37Å; L124-M141 HydrophobicContact CD2-CG 4.03Å; L124-M141 HydrophobicContact CG-CE 3.77Å; L128-M141 HydrophobicContact CD1-CE 3.78Å; A137-M141 WeakPolarHBondContact O-CB 3.33Å; A137-M141 PolarHBondContact O-N 2.9Å; C138-M141 PolarHBondContact O-N 2.74Å; S139-M141 VanDerWaalsContact C-N 3.33Å; S139-M141 PolarHBondContact O-N 2.77Å; M141-L143 VanDerWaalsContact C-N 3.32Å; M141-L143 PolarHBondContact O-N 3.12Å; M141-M144 PolarHBondContact O-N 2.86Å; M141-F145 HydrophobicContact CG-CD2 4.09Å; M141-F145 HydrophobicContact CG-CE2 3.65Å; M141-F145 WeakPolarHBondContact O-CD2 3.48Å; M141-F145 PolarHBondContact O-N 3.42Å; M141-F145 VanDerWaalsContact O-N 3.09Å; M141-F145 HydrophobicContact SD-CE2 4.37Å
142	S	93.9	Very high	92.1	Very high	0 Å²	0	57.7 Å²	57.7	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-60.5	-42	172.6	-59.4	0	0	0	0	111.6	C138 S139 F145 L146	C138-S142 WeakPolarHBondContact O-CB 3.41Å; C138-S142 PolarHBondContact O-N 3.49Å; C138-S142 PolarHBondContact O-OG 3.16Å; S139-S142 PolarHBondContact O-N 3.37Å; S142-F145 PolarHBondContact O-N 3.16Å; S142-L146 WeakPolarHBondContact O-CG 3.44Å; S142-L146 PolarHBondContact O-N 3.49Å
143	L	95.3	Very high	91.8	Very high	22 Å²	22	57.1 Å²	57.1	12%	0.115	31%	0.311	C	S	.	.	H	α-helix	trans	-61.5	-43.1	174.2	177.6	64.4	0	0	0	112.1	S139 L140 M141 F145 L146 L147 L334 Y338	S139-L143 PolarHBondContact O-N 2.91Å; L140-L143 HydrophobicContact CD1-CD2 4.31Å; L140-L143 WeakPolarHBondContact O-CB 3.22Å; L140-L143 PolarHBondContact O-N 2.74Å; M141-L143 VanDerWaalsContact C-N 3.32Å; M141-L143 PolarHBondContact O-N 3.12Å; L143-F145 VanDerWaalsContact C-N 3.34Å; L143-F145 PolarHBondContact O-N 3.45Å; L143-L146 PolarHBondContact O-N 2.76Å; L143-L146 VanDerWaalsContact O-N 3.1Å; L143-L147 PolarHBondContact O-N 2.91Å; L143-L147 VanDerWaalsContact O-N 3.12Å; L143-L334 HydrophobicContact CD1-CD1 3.84Å; L143-L334 HydrophobicContact CD1-CD2 3.88Å; L143-L334 HydrophobicContact CD1-CG 3.65Å; L143-Y338 HydrophobicContact CB-CD2 3.98Å; L143-Y338 HydrophobicContact CB-CE2 3.99Å; L143-Y338 HydrophobicContact CD1-CD2 4.18Å; L143-Y338 HydrophobicContact CD1-CG 4.29Å; L143-Y338 HydrophobicContact CD2-CD1 4.21Å; L143-Y338 HydrophobicContact CD2-CD2 4.01Å; L143-Y338 HydrophobicContact CD2-CE1 4.32Å; L143-Y338 HydrophobicContact CD2-CE2 4.09Å; L143-Y338 HydrophobicContact CD2-CG 4.07Å; L143-Y338 HydrophobicContact CG-CD2 4.29Å
144	M	94.6	Very high	91.4	Very high	98 Å²	98	59 Å²	59	48%	0.483	32%	0.319	S	S	.	.	H	α-helix	trans	-61.6	-39.9	178.2	-71.4	-65	96.3	0	0	112.6	L140 M141 L146 L147	L140-M144 VanDerWaalsContact O-CG 3.32Å; L140-M144 WeakPolarHBondContact O-CG 3.46Å; L140-M144 PolarHBondContact O-N 3.49Å; M141-M144 PolarHBondContact O-N 2.86Å; M144-L146 PolarHBondContact O-N 3.31Å; M144-L147 HydrophobicContact CE-CD2 4.3Å; M144-L147 WeakPolarHBondContact O-CB 3.14Å; M144-L147 PolarHBondContact O-N 2.81Å
145	F	93.9	Very high	91	Very high	116 Å²	116	56.7 Å²	56.7	51%	0.509	30%	0.302	S	S	.	.	H	α-helix	trans	-63.9	-26.6	175	-77.8	-61.5	0	0	0	113.5	M141 S142 L143 P148 L286	M141-F145 HydrophobicContact CG-CD2 4.09Å; M141-F145 HydrophobicContact CG-CE2 3.65Å; M141-F145 WeakPolarHBondContact O-CD2 3.48Å; M141-F145 PolarHBondContact O-N 3.42Å; M141-F145 VanDerWaalsContact O-N 3.09Å; M141-F145 HydrophobicContact SD-CE2 4.37Å; S142-F145 PolarHBondContact O-N 3.16Å; L143-F145 VanDerWaalsContact C-N 3.34Å; L143-F145 PolarHBondContact O-N 3.45Å; F145-P148 WeakPolarHBondContact O-CD 3.37Å; F145-L286 HydrophobicContact CB-CD1 3.91Å; F145-L286 HydrophobicContact CB-CD2 4Å; F145-L286 HydrophobicContact CD2-CD1 4.18Å; F145-L286 HydrophobicContact CG-CD1 4.04Å
146	L	94.9	Very high	90.7	Very high	2 Å²	2	55 Å²	55	1%	0.01	30%	0.296	C	S	.	.	H	α-helix	trans	-93.1	-10.5	-178.7	-64.7	177.5	0	0	0	113.6	L117 S142 L143 M144 P148 C149 L286 Y289 L334	L117-L146 HydrophobicContact CD2-CD1 3.56Å; L117-L146 HydrophobicContact CG-CD1 3.94Å; S142-L146 WeakPolarHBondContact O-CG 3.44Å; S142-L146 PolarHBondContact O-N 3.49Å; L143-L146 PolarHBondContact O-N 2.76Å; L143-L146 VanDerWaalsContact O-N 3.1Å; M144-L146 PolarHBondContact O-N 3.31Å; L146-P148 VanDerWaalsContact C-N 3.31Å; L146-C149 WeakPolarHBondContact O-CB 3.12Å; L146-C149 PolarHBondContact O-N 2.9Å; L146-C149 PolarHBondContact O-SG 3.26Å; L146-L286 HydrophobicContact CD1-CD2 4.27Å; L146-L286 HydrophobicContact CD2-CB 4.45Å; L146-L286 HydrophobicContact CD2-CD2 3.6Å; L146-L286 HydrophobicContact CG-CD2 3.77Å; L146-Y289 HydrophobicContact CB-CD1 4.47Å; L146-Y289 HydrophobicContact CB-CE1 4.37Å; L146-Y289 HydrophobicContact CD1-CD1 4.06Å; L146-Y289 HydrophobicContact CD1-CD2 3.71Å; L146-Y289 HydrophobicContact CD1-CE1 4.18Å; L146-Y289 HydrophobicContact CD1-CE2 3.84Å; L146-Y289 HydrophobicContact CD1-CG 3.85Å; L146-Y289 HydrophobicContact CD2-CD1 3.64Å; L146-Y289 HydrophobicContact CD2-CD2 4.39Å; L146-Y289 HydrophobicContact CD2-CE1 4.35Å; L146-Y289 HydrophobicContact CD2-CG 3.68Å; L146-Y289 HydrophobicContact CG-CD1 4.27Å; L146-Y289 HydrophobicContact CG-CG 4.36Å; L146-L334 HydrophobicContact CB-CD1 4.29Å
147	L	94.3	Very high	90.4	Very high	78 Å²	78	54 Å²	54	41%	0.408	29%	0.287	S	S	.	.	G	3₁₀ helix	trans	-55	-36.4	178	-155.9	71.6	0	0	0	114.2	L143 M144 C149 L150 L334	L143-L147 PolarHBondContact O-N 2.91Å; L143-L147 VanDerWaalsContact O-N 3.12Å; M144-L147 HydrophobicContact CE-CD2 4.3Å; M144-L147 WeakPolarHBondContact O-CB 3.14Å; M144-L147 PolarHBondContact O-N 2.81Å; L147-C149 PolarHBondContact O-N 3.11Å; L147-C149 VanDerWaalsContact O-N 3.1Å; L147-L150 HydrophobicContact CD1-CD1 3.73Å; L147-L150 HydrophobicContact CG-CD1 4.15Å; L147-L150 WeakPolarHBondContact O-CB 3.45Å; L147-L150 VanDerWaalsContact O-CG 3.24Å; L147-L150 WeakPolarHBondContact O-CG 3.49Å; L147-L150 PolarHBondContact O-N 2.95Å; L147-L150 VanDerWaalsContact O-N 3.13Å; L147-L334 HydrophobicContact CD1-CD2 4.06Å
148	P	92.8	Very high	89.9	Confident	84 Å²	84	51.9 Å²	51.9	55%	0.545	27%	0.269	S	S	.	.	G	3₁₀ helix	trans	-58.5	-21.7	173.3	-25.9	36.5	0	0	0	114.2	F145 L146 L150 L151	F145-P148 WeakPolarHBondContact O-CD 3.37Å; L146-P148 VanDerWaalsContact C-N 3.31Å; P148-L150 PolarHBondContact O-N 2.85Å; P148-L150 VanDerWaalsContact O-N 3.17Å; P148-L151 PolarHBondContact O-N 3.36Å; P148-L151 VanDerWaalsContact O-N 3.07Å
149	C	91.4	Very high	89.5	Confident	8 Å²	8	51.9 Å²	51.9	5%	0.054	27%	0.27	C	S	.	.	G	3₁₀ helix	trans	-61.9	-23.7	177.8	-61	0	0	0	0	112.8	L146 L147 L151 L152 Y289 F293	L146-C149 WeakPolarHBondContact O-CB 3.12Å; L146-C149 PolarHBondContact O-N 2.9Å; L146-C149 PolarHBondContact O-SG 3.26Å; L147-C149 PolarHBondContact O-N 3.11Å; L147-C149 VanDerWaalsContact O-N 3.1Å; C149-L151 PolarHBondContact O-N 3.13Å; C149-L151 VanDerWaalsContact O-N 3.14Å; C149-L152 HydrophobicContact CB-CD1 4.06Å; C149-L152 WeakPolarHBondContact O-CB 3.29Å; C149-L152 PolarHBondContact O-N 3.3Å; C149-L152 VanDerWaalsContact O-N 3.14Å; C149-Y289 HydrophobicContact CB-CE1 4.4Å; C149-F293 HydrophobicContact CB-CD1 3.74Å; C149-F293 HydrophobicContact CB-CE1 3.9Å; C149-F293 HydrophobicContact CB-CG 4.39Å; C149-F293 VanDerWaalsContact O-CE1 3.31Å; C149-F293 WeakPolarHBondContact O-CE1 3.49Å
150	L	92.1	Very high	89.3	Confident	23 Å²	23	56 Å²	56	12%	0.12	30%	0.295	C	S	.	.	G	3₁₀ helix	trans	-58.3	-25.5	175.4	-62.4	-178.1	0	0	0	112.6	L147 P148 F293 L327 R330 L334	L147-L150 HydrophobicContact CD1-CD1 3.73Å; L147-L150 HydrophobicContact CG-CD1 4.15Å; L147-L150 WeakPolarHBondContact O-CB 3.45Å; L147-L150 VanDerWaalsContact O-CG 3.24Å; L147-L150 WeakPolarHBondContact O-CG 3.49Å; L147-L150 PolarHBondContact O-N 2.95Å; L147-L150 VanDerWaalsContact O-N 3.13Å; P148-L150 PolarHBondContact O-N 2.85Å; P148-L150 VanDerWaalsContact O-N 3.17Å; L150-F293 HydrophobicContact CD2-CZ 3.96Å; L150-L327 HydrophobicContact CB-CD1 3.84Å; L150-L327 HydrophobicContact CD1-CD1 4.38Å; L150-R330 VanDerWaalsContact CD2-C 3.49Å; L150-R330 HydrophobicContact CD2-CB 3.85Å; L150-R330 WeakPolarHBondContact CD2-O 3.33Å; L150-R330 WeakPolarHBondContact O-CD 3.39Å; L150-L334 HydrophobicContact CD2-CB 4.26Å; L150-L334 HydrophobicContact CD2-CD2 4.08Å; L150-L334 HydrophobicContact CG-CD2 4.28Å
151	L	89.1	Confident	88.9	Confident	116 Å²	116	54 Å²	54	61%	0.607	28%	0.284	S	S	*	.	G	3₁₀ helix	trans	-95.4	-1.9	-177.2	-54.8	178.7	0	0	0	113.6	P148 C149 T153 V322	P148-L151 PolarHBondContact O-N 3.36Å; P148-L151 VanDerWaalsContact O-N 3.07Å; C149-L151 PolarHBondContact O-N 3.13Å; C149-L151 VanDerWaalsContact O-N 3.14Å; L151-T153 PolarHBondContact O-N 3.34Å; L151-T153 VanDerWaalsContact O-N 3.12Å; L151-V322 HydrophobicContact CD2-CG2 4.49Å
152	L	84.6	Confident	88.5	Confident	28 Å²	28	50.5 Å²	50.5	15%	0.147	27%	0.267	C	S	.	.			trans	-77.4	96.4	-176.3	-68.7	174.2	0	0	0	112.1	C149 P157 V158 P290 Y294 R330	C149-L152 HydrophobicContact CB-CD1 4.06Å; C149-L152 WeakPolarHBondContact O-CB 3.29Å; C149-L152 PolarHBondContact O-N 3.3Å; C149-L152 VanDerWaalsContact O-N 3.14Å; L152-P157 HydrophobicContact CD2-CB 4.18Å; L152-V158 HydrophobicContact CD1-CG2 4.35Å; L152-P290 HydrophobicContact CD1-CB 3.69Å; L152-P290 HydrophobicContact CD1-CG 4.25Å; L152-Y294 WeakPolarHBondContact O-CD2 3.46Å; L152-R330 VanDerWaalsContact O-CZ 3.23Å; L152-R330 PolarHBondContact O-NH1 3.05Å; L152-R330 PolarHBondContact O-NH2 3.1Å
153	T	81.3	Confident	88.3	Confident	66 Å²	66	53.3 Å²	53.3	41%	0.405	28%	0.281	S	S	.	.			trans	-94.9	-16.4	179.1	51.7	0	0	0	0	114.5	L151 Y294 V322	L151-T153 PolarHBondContact O-N 3.34Å; L151-T153 VanDerWaalsContact O-N 3.12Å; T153-Y294 WeakPolarHBondContact O-CE2 3.16Å; T153-Y294 PolarHBondContact O-OH 2.84Å; T153-V322 HydrophobicContact CG2-CG2 3.74Å
154	D	81.1	Confident	88	Confident	73 Å²	73	56.7 Å²	56.7	39%	0.39	30%	0.299	S	S	.	.			trans	-122.7	145.3	-172.4	-71.4	-80.9	0	0	0	112.6	R156 P157	D154-R156 VanDerWaalsContact C-N 3.31Å; D154-R156 PolarHBondContact O-N 3.37Å; D154-P157 WeakPolarHBondContact O-CD 2.83Å
155	L	81.6	Confident	87.7	Confident	34 Å²	34	52.1 Å²	52.1	18%	0.178	28%	0.277	C	S	.	.	H	α-helix	trans	-70.6	-22.1	175.9	-82.3	170.1	0	0	0	113.8	V158 S159 I224 Y294	L155-V158 WeakPolarHBondContact O-CB 3.4Å; L155-V158 PolarHBondContact O-N 3.37Å; L155-S159 PolarHBondContact O-N 3.3Å; L155-S159 PolarHBondContact O-OG 3.23Å; L155-I224 HydrophobicContact CB-CD1 4.33Å; L155-I224 HydrophobicContact CD1-CD1 3.43Å; L155-I224 VanDerWaalsContact CD1-CD1 3.43Å; L155-Y294 HydrophobicContact CD1-CE1 4Å; L155-Y294 HydrophobicContact CD2-CD1 3.41Å; L155-Y294 VanDerWaalsContact CD2-CD1 3.41Å; L155-Y294 HydrophobicContact CD2-CE1 3.3Å; L155-Y294 HydrophobicContact CD2-CG 4.34Å; L155-Y294 HydrophobicContact CG-CD1 3.99Å; L155-Y294 HydrophobicContact CG-CE1 3.33Å
156	R	83.3	Confident	87.3	Confident	110 Å²	110	46.9 Å²	46.9	42%	0.415	26%	0.255	S	S	.	.	H	α-helix	trans	-63.7	-52	-177.9	-80.9	-171.6	178.4	-152.2	-1.1	113.3	T2 I3 D154 V158 S159 V160	T2-R156 PolarHBondContact O-NE 3.4Å; T2-R156 PolarHBondContact O-NH2 3.23Å; I3-R156 HydrophobicContact CG2-CG 4.28Å; D154-R156 VanDerWaalsContact C-N 3.31Å; D154-R156 PolarHBondContact O-N 3.37Å; R156-V158 PolarHBondContact O-N 3.4Å; R156-S159 WeakPolarHBondContact O-CB 3.37Å; R156-S159 PolarHBondContact O-N 2.78Å; R156-S159 VanDerWaalsContact O-N 3.1Å; R156-V160 PolarHBondContact O-N 2.91Å
157	P	84.5	Confident	87	Confident	61 Å²	61	51.2 Å²	51.2	40%	0.396	28%	0.278	S	S	.	.	H	α-helix	trans	-54.7	-40.5	171.8	-27	34.1	0	0	0	112.7	L152 D154 S159 V160 L161	L152-P157 HydrophobicContact CD2-CB 4.18Å; D154-P157 WeakPolarHBondContact O-CD 2.83Å; P157-S159 VanDerWaalsContact C-N 3.34Å; P157-S159 PolarHBondContact O-N 2.56Å; P157-V160 PolarHBondContact O-N 2.93Å; P157-L161 VanDerWaalsContact O-CG 3.29Å; P157-L161 WeakPolarHBondContact O-CG 3.34Å; P157-L161 PolarHBondContact O-N 2.77Å
158	V	83.8	Confident	86.6	Confident	0 Å²	0	48.8 Å²	48.8	0%	0	27%	0.268	C	S	.	.	H	α-helix	trans	-62.5	-40.1	177	-179.5	0	0	0	0	111.5	L152 L155 R156 L161 S162 P290 L291 Y294	L152-V158 HydrophobicContact CD1-CG2 4.35Å; L155-V158 WeakPolarHBondContact O-CB 3.4Å; L155-V158 PolarHBondContact O-N 3.37Å; R156-V158 PolarHBondContact O-N 3.4Å; V158-L161 PolarHBondContact O-N 3.46Å; V158-S162 VanDerWaalsContact O-CB 3.32Å; V158-S162 WeakPolarHBondContact O-CB 3.44Å; V158-S162 PolarHBondContact O-N 3.3Å; V158-S162 PolarHBondContact O-OG 3.46Å; V158-P290 HydrophobicContact CG1-CB 4.4Å; V158-P290 HydrophobicContact CG2-CB 4.43Å; V158-L291 HydrophobicContact CG1-CB 3.85Å; V158-L291 HydrophobicContact CG1-CD1 3.78Å; V158-L291 HydrophobicContact CG1-CG 4.45Å; V158-Y294 HydrophobicContact CG2-CG 4.34Å
159	S	85.1	Confident	86.4	Confident	3 Å²	3	45.1 Å²	45.1	2%	0.021	24%	0.244	C	C	.	.	H	α-helix	trans	-64	-39.8	174.5	-58.1	0	0	0	0	112.7	N11 L155 R156 P157 S162 L163	N11-S159 PolarHBondContact ND2-OG 2.95Å; N11-S159 VanDerWaalsContact OD1-CA 3.27Å; N11-S159 WeakPolarHBondContact OD1-CA 3.25Å; N11-S159 PolarHBondContact OD1-OG 3.43Å; L155-S159 PolarHBondContact O-N 3.3Å; L155-S159 PolarHBondContact O-OG 3.23Å; R156-S159 WeakPolarHBondContact O-CB 3.37Å; R156-S159 PolarHBondContact O-N 2.78Å; R156-S159 VanDerWaalsContact O-N 3.1Å; P157-S159 VanDerWaalsContact C-N 3.34Å; P157-S159 PolarHBondContact O-N 2.56Å; S159-S162 WeakPolarHBondContact O-CB 3.28Å; S159-S162 PolarHBondContact O-N 3.2Å; S159-L163 PolarHBondContact O-N 3.33Å
160	V	87.8	Confident	86.3	Confident	89 Å²	89	48.9 Å²	48.9	54%	0.539	26%	0.263	S	S	.	.	H	α-helix	trans	-65.8	-42.9	176.2	176	0	0	0	0	111	R156 P157 S162 L163 L164	R156-V160 PolarHBondContact O-N 2.91Å; P157-V160 PolarHBondContact O-N 2.93Å; V160-S162 VanDerWaalsContact C-N 3.3Å; V160-S162 PolarHBondContact O-N 2.87Å; V160-L163 WeakPolarHBondContact O-CB 3.44Å; V160-L163 PolarHBondContact O-N 2.89Å; V160-L164 PolarHBondContact O-N 3.49Å
161	L	87.3	Confident	86	Confident	49 Å²	49	52.6 Å²	52.6	26%	0.257	28%	0.282	S	S	.	.	H	α-helix	trans	-63.4	-38.7	174.2	-63.8	171.4	0	0	0	111.3	P157 V158 L164 C165 L287 P290	P157-L161 VanDerWaalsContact O-CG 3.29Å; P157-L161 WeakPolarHBondContact O-CG 3.34Å; P157-L161 PolarHBondContact O-N 2.77Å; V158-L161 PolarHBondContact O-N 3.46Å; L161-L164 PolarHBondContact O-N 3.4Å; L161-C165 WeakPolarHBondContact O-CB 3.37Å; L161-C165 PolarHBondContact O-N 3.25Å; L161-L287 HydrophobicContact CD2-CD2 3.61Å; L161-P290 HydrophobicContact CD1-CB 4.1Å; L161-P290 HydrophobicContact CD1-CG 3.78Å
162	S	86.2	Confident	85.8	Confident	1 Å²	1	47.5 Å²	47.5	1%	0.007	26%	0.256	C	S	.	.	H	α-helix	trans	-64.9	-37.5	175.7	-62.9	0	0	0	0	112.6	N11 N14 V158 S159 V160 S166	N11-S162 PolarHBondContact OD1-OG 3.5Å; N14-S162 PolarHBondContact ND2-OG 2.99Å; V158-S162 VanDerWaalsContact O-CB 3.32Å; V158-S162 WeakPolarHBondContact O-CB 3.44Å; V158-S162 PolarHBondContact O-N 3.3Å; V158-S162 PolarHBondContact O-OG 3.46Å; S159-S162 WeakPolarHBondContact O-CB 3.28Å; S159-S162 PolarHBondContact O-N 3.2Å; V160-S162 VanDerWaalsContact C-N 3.3Å; V160-S162 PolarHBondContact O-N 2.87Å; S162-S166 WeakPolarHBondContact O-CB 3.43Å; S162-S166 PolarHBondContact O-N 3.4Å; S162-S166 PolarHBondContact O-OG 3.48Å
163	L	89.8	Confident	85.9	Confident	58 Å²	58	46.2 Å²	46.2	30%	0.304	25%	0.249	S	C	.	.	H	α-helix	trans	-62.3	-50.8	171.3	165.8	64.8	0	0	0	110.9	W10 S159 V160 C165 S166 L167	W10-L163 HydrophobicContact CB-CB 4.45Å; W10-L163 HydrophobicContact CD2-CD1 4.06Å; W10-L163 VanDerWaalsContact CE2-CD1 3.45Å; W10-L163 HydrophobicContact CG-CB 4.08Å; W10-L163 HydrophobicContact CG-CD1 4.27Å; W10-L163 HydrophobicContact CZ2-CD1 3.66Å; S159-L163 PolarHBondContact O-N 3.33Å; V160-L163 WeakPolarHBondContact O-CB 3.44Å; V160-L163 PolarHBondContact O-N 2.89Å; L163-C165 VanDerWaalsContact C-N 3.29Å; L163-C165 PolarHBondContact O-N 3Å; L163-S166 WeakPolarHBondContact O-CB 3.26Å; L163-S166 PolarHBondContact O-N 3.23Å; L163-S166 VanDerWaalsContact O-N 3.08Å; L163-L167 HydrophobicContact CD1-CD1 4.14Å; L163-L167 HydrophobicContact CD1-CG 4.15Å; L163-L167 HydrophobicContact CG-CD1 4.4Å; L163-L167 PolarHBondContact O-N 3.14Å
164	L	88.8	Confident	86.2	Confident	93 Å²	93	47.4 Å²	47.4	49%	0.487	25%	0.252	S	S	.	.	H	α-helix	trans	-60.8	-41.3	180	-174.7	62.8	0	0	0	111.4	V160 L161 S166 L167 A168 L287	V160-L164 PolarHBondContact O-N 3.49Å; L161-L164 PolarHBondContact O-N 3.4Å; L164-S166 PolarHBondContact O-N 3.36Å; L164-L167 PolarHBondContact O-N 2.74Å; L164-A168 WeakPolarHBondContact O-CB 3.36Å; L164-A168 PolarHBondContact O-N 2.98Å; L164-L287 HydrophobicContact CB-CD1 4.23Å; L164-L287 HydrophobicContact CD2-CD1 3.63Å; L164-L287 HydrophobicContact CD2-CD2 3.94Å; L164-L287 HydrophobicContact CD2-CG 4.45Å; L164-L287 HydrophobicContact CG-CD1 3.68Å
165	C	87.2	Confident	86.4	Confident	3 Å²	3	48.4 Å²	48.4	2%	0.02	26%	0.257	C	S	.	.	H	α-helix	trans	-57.9	-46	172.3	177.9	0	0	0	0	111.8	N14 L161 L163 L167 A168 H169 L287	N14-C165 PolarHBondContact OD1-SG 2.97Å; L161-C165 WeakPolarHBondContact O-CB 3.37Å; L161-C165 PolarHBondContact O-N 3.25Å; L163-C165 VanDerWaalsContact C-N 3.29Å; L163-C165 PolarHBondContact O-N 3Å; C165-L167 PolarHBondContact O-N 3.19Å; C165-A168 PolarHBondContact O-N 3.28Å; C165-H169 WeakPolarHBondContact O-CB 3.3Å; C165-H169 PolarHBondContact O-N 3.19Å; C165-L287 HydrophobicContact CB-CB 4.01Å
166	S	86.3	Confident	86.5	Confident	5 Å²	5	47.2 Å²	47.2	4%	0.035	25%	0.251	C	S	.	.	H	α-helix	trans	-63.5	-42.1	-179.8	-60.4	0	0	0	0	111.8	S162 L163 L164 H169 I170	S162-S166 WeakPolarHBondContact O-CB 3.43Å; S162-S166 PolarHBondContact O-N 3.4Å; S162-S166 PolarHBondContact O-OG 3.48Å; L163-S166 WeakPolarHBondContact O-CB 3.26Å; L163-S166 PolarHBondContact O-N 3.23Å; L163-S166 VanDerWaalsContact O-N 3.08Å; L164-S166 PolarHBondContact O-N 3.36Å; S166-H169 PolarHBondContact O-N 3.18Å; S166-I170 WeakPolarHBondContact O-CG1 3.44Å; S166-I170 PolarHBondContact O-N 3.14Å
167	L	88.3	Confident	86.8	Confident	94 Å²	94	43.1 Å²	43.1	49%	0.492	24%	0.237	S	C	.	.	H	α-helix	trans	-63.9	-46.9	175.3	-68.1	175.8	0	0	0	112	L163 L164 C165 H169 I170 L171	L163-L167 HydrophobicContact CD1-CD1 4.14Å; L163-L167 HydrophobicContact CD1-CG 4.15Å; L163-L167 HydrophobicContact CG-CD1 4.4Å; L163-L167 PolarHBondContact O-N 3.14Å; L164-L167 PolarHBondContact O-N 2.74Å; C165-L167 PolarHBondContact O-N 3.19Å; L167-H169 PolarHBondContact O-N 3.31Å; L167-I170 PolarHBondContact O-N 3.4Å; L167-L171 PolarHBondContact O-N 3.41Å; L167-L171 VanDerWaalsContact O-N 3.09Å
168	A	87.1	Confident	87	Confident	26 Å²	26	44.7 Å²	44.7	22%	0.215	24%	0.242	C	C	.	.	H	α-helix	trans	-58.5	-40.9	175.1	0	0	0	0	0	111	L164 C165 L171 I172	L164-A168 WeakPolarHBondContact O-CB 3.36Å; L164-A168 PolarHBondContact O-N 2.98Å; C165-A168 PolarHBondContact O-N 3.28Å; A168-L171 PolarHBondContact O-N 2.9Å; A168-I172 WeakPolarHBondContact O-CB 3.35Å; A168-I172 WeakPolarHBondContact O-CD1 3.07Å; A168-I172 WeakPolarHBondContact O-CG1 3.3Å; A168-I172 PolarHBondContact O-N 3.48Å
169	H	88.6	Confident	87.2	Confident	8 Å²	8	47.9 Å²	47.9	4%	0.037	25%	0.254	C	S	.	.	H	α-helix	trans	-65.2	-43.6	178.4	177.5	54.2	0	0	0	113.4	Q17 C165 S166 L167 L171 I172 S173 K284	Q17-H169 VanDerWaalsContact CD-NE2 3.29Å; Q17-H169 WeakPolarHBondContact CG-CD2 3.25Å; Q17-H169 WeakPolarHBondContact CG-NE2 3.06Å; Q17-H169 PolarHBondContact NE2-CE1 3.21Å; Q17-H169 PolarHBondContact NE2-NE2 3.15Å; C165-H169 WeakPolarHBondContact O-CB 3.3Å; C165-H169 PolarHBondContact O-N 3.19Å; S166-H169 PolarHBondContact O-N 3.18Å; L167-H169 PolarHBondContact O-N 3.31Å; H169-L171 VanDerWaalsContact C-N 3.3Å; H169-L171 PolarHBondContact O-N 3.38Å; H169-I172 PolarHBondContact O-N 2.89Å; H169-S173 PolarHBondContact CE1-OG 2.94Å; H169-S173 PolarHBondContact ND1-OG 2.96Å; H169-S173 PolarHBondContact NE2-OG 3.3Å; H169-S173 VanDerWaalsContact O-CB 3.31Å; H169-S173 WeakPolarHBondContact O-CB 3.43Å; H169-S173 PolarHBondContact O-N 3.5Å; H169-S173 PolarHBondContact O-OG 2.74Å; H169-K284 HydrophobicContact CB-CD 4.09Å; H169-K284 PolarHBondContact ND1-NZ 3.44Å
170	I	87.8	Confident	87.4	Confident	87 Å²	87	47.8 Å²	47.8	45%	0.446	25%	0.254	S	S	.	.	H	α-helix	trans	-58.8	-46.8	176.2	-70.4	166	0	0	0	109.6	S166 L167 S173 L174	S166-I170 WeakPolarHBondContact O-CG1 3.44Å; S166-I170 PolarHBondContact O-N 3.14Å; L167-I170 PolarHBondContact O-N 3.4Å; I170-S173 PolarHBondContact O-N 2.87Å; I170-L174 WeakPolarHBondContact O-CB 3.14Å; I170-L174 PolarHBondContact O-N 3.4Å
171	L	87.4	Confident	87.6	Confident	100 Å²	100	47.7 Å²	47.7	52%	0.524	25%	0.25	S	C	.	.	H	α-helix	trans	-60.7	-50.6	178.7	-179.2	65	0	0	0	111.9	L167 A168 H169 S173 L174 L175	L167-L171 PolarHBondContact O-N 3.41Å; L167-L171 VanDerWaalsContact O-N 3.09Å; A168-L171 PolarHBondContact O-N 2.9Å; H169-L171 VanDerWaalsContact C-N 3.3Å; H169-L171 PolarHBondContact O-N 3.38Å; L171-S173 VanDerWaalsContact C-N 3.33Å; L171-S173 PolarHBondContact O-N 3Å; L171-L174 PolarHBondContact O-N 3.01Å; L171-L175 HydrophobicContact CG-CD1 4.31Å; L171-L175 WeakPolarHBondContact O-CG 3.34Å; L171-L175 PolarHBondContact O-N 2.92Å
172	I	85.1	Confident	87.8	Confident	10 Å²	10	49.5 Å²	49.5	5%	0.051	27%	0.267	C	S	.	.	H	α-helix	trans	-62.1	-43.1	-179.1	-65.6	160.6	0	0	0	110.7	A168 H169 L174 L175 V176 V277 C280 L281 K284	A168-I172 WeakPolarHBondContact O-CB 3.35Å; A168-I172 WeakPolarHBondContact O-CD1 3.07Å; A168-I172 WeakPolarHBondContact O-CG1 3.3Å; A168-I172 PolarHBondContact O-N 3.48Å; H169-I172 PolarHBondContact O-N 2.89Å; I172-L174 PolarHBondContact O-N 2.69Å; I172-L175 PolarHBondContact O-N 2.96Å; I172-V176 HydrophobicContact CG2-CG2 4.45Å; I172-V176 WeakPolarHBondContact O-CG2 3.32Å; I172-V176 PolarHBondContact O-N 3.02Å; I172-V277 HydrophobicContact CG2-CG1 4.39Å; I172-C280 HydrophobicContact CD1-CB 3.79Å; I172-C280 HydrophobicContact CG1-CB 4Å; I172-L281 HydrophobicContact CD1-CD2 3.78Å; I172-L281 HydrophobicContact CD1-CG 4.01Å; I172-L281 HydrophobicContact CG2-CD1 4.42Å; I172-L281 HydrophobicContact CG2-CD2 3.83Å; I172-L281 HydrophobicContact CG2-CG 4.06Å; I172-K284 HydrophobicContact CD1-CB 4.44Å; I172-K284 HydrophobicContact CD1-CD 4.35Å
173	S	85	Confident	88	Confident	1 Å²	1	50.8 Å²	50.8	1%	0.007	28%	0.275	C	S	.	.	H	α-helix	trans	-64.1	-42.4	178.6	-55.2	0	0	0	0	111.5	H169 I170 L171 L175 V176 I177	H169-S173 PolarHBondContact CE1-OG 2.94Å; H169-S173 PolarHBondContact ND1-OG 2.96Å; H169-S173 PolarHBondContact NE2-OG 3.3Å; H169-S173 VanDerWaalsContact O-CB 3.31Å; H169-S173 WeakPolarHBondContact O-CB 3.43Å; H169-S173 PolarHBondContact O-N 3.5Å; H169-S173 PolarHBondContact O-OG 2.74Å; I170-S173 PolarHBondContact O-N 2.87Å; L171-S173 VanDerWaalsContact C-N 3.33Å; L171-S173 PolarHBondContact O-N 3Å; S173-L175 VanDerWaalsContact C-N 3.35Å; S173-L175 PolarHBondContact O-N 3.44Å; S173-V176 PolarHBondContact O-N 3.21Å; S173-I177 VanDerWaalsContact O-CB 3.27Å; S173-I177 WeakPolarHBondContact O-CB 3.41Å; S173-I177 WeakPolarHBondContact O-CD1 3.41Å; S173-I177 WeakPolarHBondContact O-CG1 3.24Å; S173-I177 PolarHBondContact O-N 3.3Å
174	L	87.4	Confident	88	Confident	90 Å²	90	50.1 Å²	50.1	47%	0.471	28%	0.278	S	S	.	.	H	α-helix	trans	-59.4	-46.3	175.7	179.3	63.8	0	0	0	111	I170 L171 I172 I177 L178	I170-L174 WeakPolarHBondContact O-CB 3.14Å; I170-L174 PolarHBondContact O-N 3.4Å; L171-L174 PolarHBondContact O-N 3.01Å; I172-L174 PolarHBondContact O-N 2.69Å; L174-I177 PolarHBondContact O-N 3.15Å; L174-L178 HydrophobicContact CD1-CD1 4.14Å; L174-L178 HydrophobicContact CD1-CG 4.18Å; L174-L178 HydrophobicContact CG-CD1 3.98Å; L174-L178 HydrophobicContact CG-CG 4.42Å; L174-L178 WeakPolarHBondContact O-CB 3.41Å; L174-L178 VanDerWaalsContact O-CG 3.22Å; L174-L178 WeakPolarHBondContact O-CG 3.26Å; L174-L178 PolarHBondContact O-N 2.93Å
175	L	85.5	Confident	88.1	Confident	94 Å²	94	50.7 Å²	50.7	49%	0.492	29%	0.29	S	S	.	.	H	α-helix	trans	-60.8	-46.4	178.3	-69.6	172.6	0	0	0	112.2	L171 I172 S173 L178 Y179	L171-L175 HydrophobicContact CG-CD1 4.31Å; L171-L175 WeakPolarHBondContact O-CG 3.34Å; L171-L175 PolarHBondContact O-N 2.92Å; I172-L175 PolarHBondContact O-N 2.96Å; S173-L175 VanDerWaalsContact C-N 3.35Å; S173-L175 PolarHBondContact O-N 3.44Å; L175-L178 PolarHBondContact O-N 2.85Å; L175-Y179 PolarHBondContact O-N 3.18Å
176	V	84.1	Confident	88.2	Confident	10 Å²	10	56.6 Å²	56.6	6%	0.061	32%	0.321	C	S	.	.	H	α-helix	trans	-65	-42.4	178.2	174.1	0	0	0	0	111.1	I172 S173 Y179 C180 F249	I172-V176 HydrophobicContact CG2-CG2 4.45Å; I172-V176 WeakPolarHBondContact O-CG2 3.32Å; I172-V176 PolarHBondContact O-N 3.02Å; S173-V176 PolarHBondContact O-N 3.21Å; V176-Y179 PolarHBondContact O-N 3.19Å; V176-C180 PolarHBondContact O-N 3.03Å; V176-C180 PolarHBondContact O-SG 2.93Å; V176-F249 HydrophobicContact CB-CD2 4.36Å; V176-F249 HydrophobicContact CB-CE2 3.73Å; V176-F249 HydrophobicContact CG1-CD2 4.16Å; V176-F249 HydrophobicContact CG1-CE2 3.53Å; V176-F249 HydrophobicContact CG1-CZ 4.11Å; V176-F249 HydrophobicContact CG2-CE2 4.09Å
177	I	89.3	Confident	88.5	Confident	23 Å²	23	59.4 Å²	59.4	12%	0.118	33%	0.331	C	S	.	.	H	α-helix	trans	-61.4	-45.9	176.7	-74	167.5	0	0	0	110.7	S173 L174 Y179 C180 L181 T248 L252	S173-I177 VanDerWaalsContact O-CB 3.27Å; S173-I177 WeakPolarHBondContact O-CB 3.41Å; S173-I177 WeakPolarHBondContact O-CD1 3.41Å; S173-I177 WeakPolarHBondContact O-CG1 3.24Å; S173-I177 PolarHBondContact O-N 3.3Å; L174-I177 PolarHBondContact O-N 3.15Å; I177-Y179 VanDerWaalsContact C-N 3.33Å; I177-Y179 PolarHBondContact O-N 3.33Å; I177-C180 PolarHBondContact O-N 3.28Å; I177-L181 HydrophobicContact CG2-CD1 3.85Å; I177-L181 HydrophobicContact CG2-CG 4.42Å; I177-L181 WeakPolarHBondContact O-CB 3.29Å; I177-L181 VanDerWaalsContact O-CG 3.27Å; I177-L181 WeakPolarHBondContact O-CG 3.41Å; I177-L181 PolarHBondContact O-N 2.88Å; I177-T248 HydrophobicContact CD1-CG2 4.02Å; I177-T248 HydrophobicContact CG1-CG2 4.45Å; I177-L252 HydrophobicContact CB-CD1 4.34Å; I177-L252 HydrophobicContact CG1-CD1 4.25Å; I177-L252 HydrophobicContact CG2-CD1 3.74Å
178	L	90.3	Very high	88.4	Confident	95 Å²	95	56.7 Å²	56.7	50%	0.497	32%	0.32	S	S	.	.	H	α-helix	trans	-62.3	-40.7	177.3	-71.9	172.1	0	0	0	111.8	L174 L175 L181 S182	L174-L178 HydrophobicContact CD1-CD1 4.14Å; L174-L178 HydrophobicContact CD1-CG 4.18Å; L174-L178 HydrophobicContact CG-CD1 3.98Å; L174-L178 HydrophobicContact CG-CG 4.42Å; L174-L178 WeakPolarHBondContact O-CB 3.41Å; L174-L178 VanDerWaalsContact O-CG 3.22Å; L174-L178 WeakPolarHBondContact O-CG 3.26Å; L174-L178 PolarHBondContact O-N 2.93Å; L175-L178 PolarHBondContact O-N 2.85Å; L178-L181 PolarHBondContact O-N 2.77Å; L178-S182 PolarHBondContact O-N 3.14Å
179	Y	87.6	Confident	88.4	Confident	66 Å²	66	62.2 Å²	62.2	26%	0.259	34%	0.336	S	S	.	.	H	α-helix	trans	-61.1	-49.3	173.2	177.6	-98	0	0	0	111.6	L175 V176 I177 L181 S182 C183 W257 L269 P270 L273	L175-Y179 PolarHBondContact O-N 3.18Å; V176-Y179 PolarHBondContact O-N 3.19Å; I177-Y179 VanDerWaalsContact C-N 3.33Å; I177-Y179 PolarHBondContact O-N 3.33Å; Y179-L181 VanDerWaalsContact C-N 3.28Å; Y179-L181 PolarHBondContact O-N 3.37Å; Y179-S182 WeakPolarHBondContact O-CB 3.45Å; Y179-S182 PolarHBondContact O-N 3.41Å; Y179-S182 PolarHBondContact O-OG 2.62Å; Y179-C183 PolarHBondContact O-N 3.09Å; Y179-W257 HydrophobicContact CD1-CH2 4.09Å; Y179-W257 HydrophobicContact CD1-CZ2 4.06Å; Y179-W257 HydrophobicContact CE1-CH2 4.1Å; Y179-W257 AromaticContact CE1-CZ2 3.59Å; Y179-W257 HydrophobicContact CE1-CZ2 3.59Å; Y179-L269 HydrophobicContact CD1-CD2 4.45Å; Y179-P270 HydrophobicContact CE2-CG 4.3Å; Y179-L273 HydrophobicContact CD2-CD1 4.23Å; Y179-L273 HydrophobicContact CE2-CD1 4.38Å
180	C	89.5	Confident	88.2	Confident	1 Å²	1	66.2 Å²	66.2	1%	0.007	37%	0.365	C	S	.	.	H	α-helix	trans	-59.1	-41.1	178.1	-64.3	0	0	0	0	111.5	V176 I177 S182 C183 A184 W187 L252 T256	V176-C180 PolarHBondContact O-N 3.03Å; V176-C180 PolarHBondContact O-SG 2.93Å; I177-C180 PolarHBondContact O-N 3.28Å; C180-S182 VanDerWaalsContact C-N 3.32Å; C180-S182 PolarHBondContact O-N 3.25Å; C180-C183 CarbonylContact O-C 3.57Å; C180-C183 WeakPolarHBondContact O-CA 3.47Å; C180-C183 WeakPolarHBondContact O-CB 3.45Å; C180-C183 PolarHBondContact O-N 3.17Å; C180-A184 PolarHBondContact O-N 2.59Å; C180-W187 VanDerWaalsContact O-CZ2 3.29Å; C180-W187 WeakPolarHBondContact O-CZ2 3.18Å; C180-W187 PolarHBondContact O-NE1 3.2Å; C180-L252 HydrophobicContact CB-CB 3.87Å; C180-T256 WeakPolarHBondContact CB-OG1 3.31Å
181	L	92.2	Very high	87.8	Confident	87 Å²	87	65.3 Å²	65.3	46%	0.455	36%	0.358	S	S	.	.	H	α-helix	trans	-63.5	-35.3	175.4	-72.6	168	0	0	0	112.4	I177 L178 Y179 C183 A184 W187 L252	I177-L181 HydrophobicContact CG2-CD1 3.85Å; I177-L181 HydrophobicContact CG2-CG 4.42Å; I177-L181 WeakPolarHBondContact O-CB 3.29Å; I177-L181 VanDerWaalsContact O-CG 3.27Å; I177-L181 WeakPolarHBondContact O-CG 3.41Å; I177-L181 PolarHBondContact O-N 2.88Å; L178-L181 PolarHBondContact O-N 2.77Å; Y179-L181 VanDerWaalsContact C-N 3.28Å; Y179-L181 PolarHBondContact O-N 3.37Å; L181-C183 PolarHBondContact O-N 2.97Å; L181-A184 WeakPolarHBondContact O-CB 3.46Å; L181-A184 PolarHBondContact O-N 3.33Å; L181-A184 VanDerWaalsContact O-N 3.14Å; L181-W187 HydrophobicContact CD2-CH2 3.75Å; L181-W187 HydrophobicContact CD2-CZ2 4.31Å; L181-L252 HydrophobicContact CD2-CD1 4.45Å; L181-L252 HydrophobicContact CG-CD1 4.33Å
182	S	91.3	Very high	87.4	Confident	88 Å²	88	60.9 Å²	60.9	62%	0.615	33%	0.334	S	S	*	.	H	α-helix	trans	-64.3	-23.2	173.6	79.8	0	0	0	0	113	L178 Y179 C180	L178-S182 PolarHBondContact O-N 3.14Å; Y179-S182 WeakPolarHBondContact O-CB 3.45Å; Y179-S182 PolarHBondContact O-N 3.41Å; Y179-S182 PolarHBondContact O-OG 2.62Å; C180-S182 VanDerWaalsContact C-N 3.32Å; C180-S182 PolarHBondContact O-N 3.25Å
183	C	89.1	Confident	87.2	Confident	27 Å²	27	62.7 Å²	62.7	18%	0.182	35%	0.348	C	S	.	.	T	Hydrogen-bonded Turn	trans	-93.9	9.1	176.8	-59.4	0	0	0	0	113.5	Y179 C180 L181 S185 N186 T256	Y179-C183 PolarHBondContact O-N 3.09Å; C180-C183 CarbonylContact O-C 3.57Å; C180-C183 WeakPolarHBondContact O-CA 3.47Å; C180-C183 WeakPolarHBondContact O-CB 3.45Å; C180-C183 PolarHBondContact O-N 3.17Å; L181-C183 PolarHBondContact O-N 2.97Å; C183-S185 PolarHBondContact O-N 2.9Å; C183-S185 VanDerWaalsContact O-N 3.09Å; C183-N186 PolarHBondContact O-N 3.16Å; C183-T256 HydrophobicContact CB-CG2 3.89Å
184	A	91.1	Very high	86.8	Confident	44 Å²	44	69.5 Å²	69.5	36%	0.364	38%	0.383	S	S	.	.	G	3₁₀ helix	trans	-60.6	-24.3	-171	0	0	0	0	0	115	C180 L181 N186 W187	C180-A184 PolarHBondContact O-N 2.59Å; L181-A184 WeakPolarHBondContact O-CB 3.46Å; L181-A184 PolarHBondContact O-N 3.33Å; L181-A184 VanDerWaalsContact O-N 3.14Å; A184-N186 PolarHBondContact O-N 2.81Å; A184-W187 HydrophobicContact CB-CD2 4Å; A184-W187 HydrophobicContact CB-CE3 4.13Å; A184-W187 HydrophobicContact CB-CH2 4.1Å; A184-W187 HydrophobicContact CB-CZ2 3.99Å; A184-W187 HydrophobicContact CB-CZ3 4.18Å; A184-W187 PolarHBondContact O-N 3.37Å
185	S	90.9	Very high	86.2	Confident	106 Å²	106	70.4 Å²	70.4	74%	0.741	40%	0.397	S	S	*	.	G	3₁₀ helix	trans	-62.5	-23.6	175.2	62.3	0	0	0	0	113.3	C183	C183-S185 PolarHBondContact O-N 2.9Å; C183-S185 VanDerWaalsContact O-N 3.09Å
186	N	88	Confident	86.2	Confident	127 Å²	127	67.7 Å²	67.7	68%	0.679	39%	0.385	S	S	*	.	G	3₁₀ helix	trans	-104.5	5.8	-174	-59.5	-9.5	0	0	0	112.4	C183 A184	C183-N186 PolarHBondContact O-N 3.16Å; A184-N186 PolarHBondContact O-N 2.81Å
187	W	92.3	Very high	86.4	Confident	63 Å²	63	70.9 Å²	70.9	24%	0.239	40%	0.401	C	S	.	.			trans	-68	135.3	-178	-72.7	-6.3	0	0	0	112	C180 L181 A184 L252 L255 T256	C180-W187 VanDerWaalsContact O-CZ2 3.29Å; C180-W187 WeakPolarHBondContact O-CZ2 3.18Å; C180-W187 PolarHBondContact O-NE1 3.2Å; L181-W187 HydrophobicContact CD2-CH2 3.75Å; L181-W187 HydrophobicContact CD2-CZ2 4.31Å; A184-W187 HydrophobicContact CB-CD2 4Å; A184-W187 HydrophobicContact CB-CE3 4.13Å; A184-W187 HydrophobicContact CB-CH2 4.1Å; A184-W187 HydrophobicContact CB-CZ2 3.99Å; A184-W187 HydrophobicContact CB-CZ3 4.18Å; A184-W187 PolarHBondContact O-N 3.37Å; W187-L252 HydrophobicContact CH2-CD2 3.32Å; W187-L252 HydrophobicContact CZ2-CD2 3.74Å; W187-L252 HydrophobicContact CZ3-CD2 4Å; W187-L255 WeakPolarHBondContact CA-O 3.15Å; W187-L255 HydrophobicContact CB-CB 4.14Å; W187-L255 VanDerWaalsContact CD1-O 3.26Å; W187-L255 HydrophobicContact CD2-CB 3.88Å; W187-L255 HydrophobicContact CD2-CD1 4.14Å; W187-L255 HydrophobicContact CE3-CB 4.45Å; W187-L255 HydrophobicContact CE3-CD1 3.86Å; W187-L255 HydrophobicContact CG-CB 3.73Å; W187-L255 HydrophobicContact CZ3-CD1 4.22Å; W187-T256 PolarHBondContact NE1-OG1 2.72Å; W187-T256 VanDerWaalsContact NE1-OG1 3.11Å
188	S	87.3	Confident	86.4	Confident	38 Å²	38	74.3 Å²	74.3	27%	0.266	43%	0.425	S	S	.	.			trans	-124.3	125.5	171.5	-171	0	0	0	0	111.8	S190 F191	S188-S190 PolarHBondContact O-N 3.49Å; S188-S190 PolarHBondContact OG-N 2.83Å; S188-S190 PolarHBondContact OG-OG 3.32Å; S188-F191 VanDerWaalsContact O-CD2 3.23Å; S188-F191 WeakPolarHBondContact O-CD2 3.39Å
189	W	87.1	Confident	86.4	Confident	142 Å²	142	72.7 Å²	72.7	54%	0.538	42%	0.415	S	S	.	.	G	3₁₀ helix	trans	-75.4	-10.6	173.2	-65.2	92.6	0	0	0	113	Y33 F191 L192 L251 L255	Y33-W189 PolarHBondContact OH-O 2.93Å; W189-F191 PolarHBondContact O-N 2.97Å; W189-L192 HydrophobicContact CE3-CD1 4.47Å; W189-L192 PolarHBondContact O-N 2.83Å; W189-L251 HydrophobicContact CH2-CD2 4.46Å; W189-L251 HydrophobicContact CZ3-CD1 4.1Å; W189-L255 HydrophobicContact CD2-CD2 3.8Å; W189-L255 HydrophobicContact CE3-CD2 3.83Å; W189-L255 HydrophobicContact CG-CD2 4.27Å; W189-L255 HydrophobicContact CH2-CD1 3.84Å; W189-L255 HydrophobicContact CH2-CD2 4.42Å; W189-L255 HydrophobicContact CZ2-CD1 3.88Å; W189-L255 HydrophobicContact CZ2-CD2 4.39Å; W189-L255 HydrophobicContact CZ3-CD1 4.26Å; W189-L255 HydrophobicContact CZ3-CD2 4.15Å
190	S	83.5	Confident	86.6	Confident	92 Å²	92	71.9 Å²	71.9	64%	0.643	42%	0.415	S	S	*	.	G	3₁₀ helix	trans	-70.1	-15.8	175	67.6	0	0	0	0	113.1	S188 L192	S188-S190 PolarHBondContact O-N 3.49Å; S188-S190 PolarHBondContact OG-N 2.83Å; S188-S190 PolarHBondContact OG-OG 3.32Å; S190-L192 VanDerWaalsContact C-N 3.26Å; S190-L192 PolarHBondContact O-N 2.89Å
191	F	79.3	Confident	86.8	Confident	68 Å²	68	74.2 Å²	74.2	30%	0.298	43%	0.425	S	S	.	.	G	3₁₀ helix	trans	-70.8	-22.2	176.7	-59.3	-33.5	0	0	0	113.1	S188 W189 P259	S188-F191 VanDerWaalsContact O-CD2 3.23Å; S188-F191 WeakPolarHBondContact O-CD2 3.39Å; W189-F191 PolarHBondContact O-N 2.97Å; F191-P259 HydrophobicContact CD1-CG 4.23Å
192	L	80.4	Confident	86.8	Confident	7 Å²	7	71.5 Å²	71.5	4%	0.037	41%	0.411	C	S	.	.	S	Bend	trans	-88.9	104.4	169.1	-73	167.6	0	0	0	108.5	Y33 W189 S190 L251 V254	Y33-L192 HydrophobicContact CD1-CB 4.3Å; Y33-L192 HydrophobicContact CD1-CD1 4.1Å; Y33-L192 HydrophobicContact CD2-CB 3.82Å; Y33-L192 HydrophobicContact CE1-CB 3.96Å; Y33-L192 HydrophobicContact CE1-CD1 3.61Å; Y33-L192 HydrophobicContact CE1-CG 4.42Å; Y33-L192 HydrophobicContact CE2-CB 3.44Å; Y33-L192 VanDerWaalsContact CE2-CB 3.44Å; Y33-L192 WeakPolarHBondContact CE2-O 3.23Å; Y33-L192 HydrophobicContact CG-CB 4.23Å; Y33-L192 VanDerWaalsContact CZ-CB 3.49Å; W189-L192 HydrophobicContact CE3-CD1 4.47Å; W189-L192 PolarHBondContact O-N 2.83Å; S190-L192 VanDerWaalsContact C-N 3.26Å; S190-L192 PolarHBondContact O-N 2.89Å; L192-L251 HydrophobicContact CD1-CD1 3.82Å; L192-V254 HydrophobicContact CD2-CG1 3.89Å; L192-V254 HydrophobicContact CG-CG1 4.01Å
193	S	80.1	Confident	86.9	Confident	48 Å²	48	67.4 Å²	67.4	34%	0.336	38%	0.382	S	S	.	.			trans	-81.8	151.1	175.5	65.7	0	0	0	0	111.5	G32 Y33 S195	G32-S193 VanDerWaalsContact CA-O 3.3Å; G32-S193 WeakPolarHBondContact CA-O 3.2Å; Y33-S193 PolarHBondContact N-O 3.33Å; S193-S195 VanDerWaalsContact CB-O 3.29Å; S193-S195 WeakPolarHBondContact CB-O 3.39Å; S193-S195 PolarHBondContact OG-O 3.43Å
194	L	76.1	Confident	87.2	Confident	144 Å²	144	66.1 Å²	66.1	75%	0.754	37%	0.373	S	S	*	.	S	Bend	trans	-85.3	-27.7	166.1	-98.2	151	0	0	0	111.7	Y33	Y33-L194 HydrophobicContact CD2-CG 4.33Å
195	S	75.9	Confident	87.4	Confident	108 Å²	108	64.5 Å²	64.5	76%	0.755	36%	0.359	S	S	*	.	S	Bend	trans	-97.5	125.6	175.3	-173.1	0	0	0	0	109.4	S193	S193-S195 VanDerWaalsContact CB-O 3.29Å; S193-S195 WeakPolarHBondContact CB-O 3.39Å; S193-S195 PolarHBondContact OG-O 3.43Å
196	V	84.3	Confident	87.7	Confident	38 Å²	38	59.4 Å²	59.4	23%	0.23	32%	0.323	C	S	.	.			trans	-135.8	145.2	-172.8	-176.7	0	0	0	0	109.2	Q30 P198 F201	Q30-V196 WeakPolarHBondContact O-CG1 3.46Å; V196-P198 WeakPolarHBondContact O-CD 3.37Å; V196-F201 HydrophobicContact CG1-CB 3.9Å
197	D	89.1	Confident	88	Confident	77 Å²	77	53.5 Å²	53.5	41%	0.412	29%	0.292	S	S	.	.			trans	-60	124.7	169.9	176.9	-96.9	0	0	0	110.5	E199 D200 F201 K408	D197-E199 VanDerWaalsContact C-N 3.27Å; D197-E199 PolarHBondContact O-N 3.43Å; D197-E199 WeakPolarHBondContact OD1-CA 3.22Å; D197-E199 WeakPolarHBondContact OD1-CB 3.28Å; D197-E199 PolarHBondContact OD1-N 2.98Å; D197-D200 HydrophobicContact CB-CB 4.16Å; D197-D200 PolarHBondContact O-N 3.04Å; D197-D200 PolarHBondContact OD1-N 2.88Å; D197-F201 WeakPolarHBondContact O-CB 3.37Å; D197-F201 PolarHBondContact O-N 2.97Å; D197-K408 IonicContact OD1-NZ 3.21Å
198	P	89.7	Confident	88.2	Confident	94 Å²	94	50.5 Å²	50.5	61%	0.61	28%	0.28	S	S	*	.	H	α-helix	trans	-59.3	-34.2	-176.7	-26.4	34.9	0	0	0	114	V196 I202	V196-P198 WeakPolarHBondContact O-CD 3.37Å; P198-I202 WeakPolarHBondContact O-CB 3.01Å; P198-I202 VanDerWaalsContact O-CG1 3.22Å; P198-I202 WeakPolarHBondContact O-CG1 3.28Å; P198-I202 PolarHBondContact O-N 3.23Å; P198-I202 VanDerWaalsContact O-N 3.09Å
199	E	90.4	Very high	88.6	Confident	61 Å²	61	49 Å²	49	29%	0.285	27%	0.269	S	S	.	.	H	α-helix	trans	-74.4	-40.5	-179	-59.3	-173.4	-176	0	0	111.2	D197 V203 C404 K407	D197-E199 VanDerWaalsContact C-N 3.27Å; D197-E199 PolarHBondContact O-N 3.43Å; D197-E199 WeakPolarHBondContact OD1-CA 3.22Å; D197-E199 WeakPolarHBondContact OD1-CB 3.28Å; D197-E199 PolarHBondContact OD1-N 2.98Å; E199-V203 WeakPolarHBondContact O-CG2 3.23Å; E199-V203 PolarHBondContact O-N 3.46Å; E199-V203 VanDerWaalsContact O-N 3.16Å; E199-C404 HydrophobicContact CB-CB 4.46Å; E199-K407 VanDerWaalsContact CD-NZ 3.29Å; E199-K407 IonicContact OE1-NZ 3.47Å; E199-K407 PolarHBondContact OE1-NZ 3.09Å; E199-K407 IonicContact OE2-NZ 3.71Å; E199-K407 PolarHBondContact OE2-NZ 3.12Å; E199-K407 VanDerWaalsContact OE2-NZ 3.14Å
200	D	90.9	Very high	89	Confident	49 Å²	49	42.3 Å²	42.3	26%	0.262	24%	0.244	S	C	.	.	H	α-helix	trans	-67	-39.1	174.5	-75.7	-38.1	0	0	0	111.8	Q30 D197 I202 V203 S204 K408	Q30-D200 HydrophobicContact CB-CB 4.19Å; Q30-D200 HydrophobicContact CG-CB 4.38Å; Q30-D200 PolarHBondContact NE2-OD1 3.38Å; D197-D200 HydrophobicContact CB-CB 4.16Å; D197-D200 PolarHBondContact O-N 3.04Å; D197-D200 PolarHBondContact OD1-N 2.88Å; D200-I202 PolarHBondContact O-N 2.9Å; D200-V203 PolarHBondContact O-N 3.41Å; D200-S204 WeakPolarHBondContact O-CB 3.4Å; D200-S204 PolarHBondContact O-N 3.44Å; D200-S204 PolarHBondContact O-OG 3.11Å; D200-K408 IonicContact OD1-NZ 3.56Å; D200-K408 PolarHBondContact OD1-NZ 3.08Å; D200-K408 IonicContact OD2-NZ 2.65Å
201	F	93.1	Very high	89.6	Confident	50 Å²	50	37.9 Å²	37.9	22%	0.219	21%	0.213	C	C	.	.	H	α-helix	trans	-57.8	-50.5	174.1	174.9	-104.4	0	0	0	111.3	V34 V196 D197 V203 S204 V205	V34-F201 HydrophobicContact CB-CE2 3.92Å; V34-F201 HydrophobicContact CG1-CE2 3.48Å; V34-F201 VanDerWaalsContact CG1-CE2 3.48Å; V34-F201 HydrophobicContact CG1-CZ 3.63Å; V196-F201 HydrophobicContact CG1-CB 3.9Å; D197-F201 WeakPolarHBondContact O-CB 3.37Å; D197-F201 PolarHBondContact O-N 2.97Å; F201-V203 PolarHBondContact O-N 3.28Å; F201-S204 WeakPolarHBondContact O-CB 3.42Å; F201-S204 PolarHBondContact O-N 3.26Å; F201-S204 VanDerWaalsContact O-N 3.16Å; F201-V205 HydrophobicContact CD1-CG2 4.32Å; F201-V205 HydrophobicContact CE1-CG2 3.82Å; F201-V205 HydrophobicContact CE2-CG2 4.02Å; F201-V205 HydrophobicContact CZ-CG2 3.65Å; F201-V205 WeakPolarHBondContact O-CG2 3.46Å; F201-V205 PolarHBondContact O-N 2.93Å
202	I	93.6	Very high	90.4	Very high	31 Å²	31	34.7 Å²	34.7	16%	0.159	20%	0.199	C	C	.	.	H	α-helix	trans	-64.9	-39.8	-177.9	-71.6	-65	0	0	0	111.9	P198 D200 S204 V205 G206 A400 G401 C404	P198-I202 WeakPolarHBondContact O-CB 3.01Å; P198-I202 VanDerWaalsContact O-CG1 3.22Å; P198-I202 WeakPolarHBondContact O-CG1 3.28Å; P198-I202 PolarHBondContact O-N 3.23Å; P198-I202 VanDerWaalsContact O-N 3.09Å; D200-I202 PolarHBondContact O-N 2.9Å; I202-S204 VanDerWaalsContact C-N 3.32Å; I202-S204 PolarHBondContact O-N 3.16Å; I202-V205 PolarHBondContact O-N 3.47Å; I202-G206 PolarHBondContact O-N 2.72Å; I202-G206 VanDerWaalsContact O-N 3.16Å; I202-A400 HydrophobicContact CD1-CB 4.1Å; I202-A400 HydrophobicContact CG1-CB 4.37Å; I202-A400 HydrophobicContact CG2-CB 3.97Å; I202-G401 VanDerWaalsContact CG2-CA 3.42Å; I202-C404 HydrophobicContact CG2-CB 4.16Å
203	V	93.1	Very high	91.1	Very high	2 Å²	2	34.8 Å²	34.8	1%	0.012	20%	0.2	C	C	.	.	H	α-helix	trans	-62.5	-41.3	173.6	172	0	0	0	0	110.9	E199 D200 F201 V205 G206 V207 L349 C404 K408	E199-V203 WeakPolarHBondContact O-CG2 3.23Å; E199-V203 PolarHBondContact O-N 3.46Å; E199-V203 VanDerWaalsContact O-N 3.16Å; D200-V203 PolarHBondContact O-N 3.41Å; F201-V203 PolarHBondContact O-N 3.28Å; V203-V205 PolarHBondContact O-N 3.29Å; V203-G206 WeakPolarHBondContact O-CA 3.33Å; V203-G206 PolarHBondContact O-N 3.07Å; V203-G206 VanDerWaalsContact O-N 3.12Å; V203-V207 PolarHBondContact O-N 3.04Å; V203-L349 HydrophobicContact CG1-CD2 4.32Å; V203-C404 HydrophobicContact CG2-CB 4.23Å; V203-K408 HydrophobicContact CG2-CD 4.24Å
204	S	95.1	Very high	91.8	Very high	0 Å²	0	32.6 Å²	32.6	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-64.6	-37.8	177.6	-62.5	0	0	0	0	112.8	A27 Q30 D200 F201 I202 G206 V207 I208	A27-S204 WeakPolarHBondContact O-CB 3.31Å; A27-S204 PolarHBondContact O-OG 3.19Å; Q30-S204 WeakPolarHBondContact CB-OG 3.17Å; Q30-S204 PolarHBondContact OE1-OG 3.34Å; D200-S204 WeakPolarHBondContact O-CB 3.4Å; D200-S204 PolarHBondContact O-N 3.44Å; D200-S204 PolarHBondContact O-OG 3.11Å; F201-S204 WeakPolarHBondContact O-CB 3.42Å; F201-S204 PolarHBondContact O-N 3.26Å; F201-S204 VanDerWaalsContact O-N 3.16Å; I202-S204 VanDerWaalsContact C-N 3.32Å; I202-S204 PolarHBondContact O-N 3.16Å; S204-G206 VanDerWaalsContact C-N 3.29Å; S204-G206 PolarHBondContact O-N 2.99Å; S204-V207 WeakPolarHBondContact O-CB 3.4Å; S204-V207 PolarHBondContact O-N 2.98Å; S204-I208 VanDerWaalsContact O-CG1 3.32Å; S204-I208 WeakPolarHBondContact O-CG1 3.31Å; S204-I208 PolarHBondContact O-N 2.93Å
205	V	95.7	Very high	92.7	Very high	9 Å²	9	25.8 Å²	25.8	6%	0.055	15%	0.149	C	C	.	.	H	α-helix	trans	-59.9	-42.7	171.5	172	0	0	0	0	110.3	V38 F201 I202 V203 I208 I209	V38-V205 HydrophobicContact CG1-CG1 4.43Å; V38-V205 HydrophobicContact CG1-CG2 4.35Å; F201-V205 HydrophobicContact CD1-CG2 4.32Å; F201-V205 HydrophobicContact CE1-CG2 3.82Å; F201-V205 HydrophobicContact CE2-CG2 4.02Å; F201-V205 HydrophobicContact CZ-CG2 3.65Å; F201-V205 WeakPolarHBondContact O-CG2 3.46Å; F201-V205 PolarHBondContact O-N 2.93Å; I202-V205 PolarHBondContact O-N 3.47Å; V203-V205 PolarHBondContact O-N 3.29Å; V205-I208 PolarHBondContact O-N 3.23Å; V205-I209 HydrophobicContact CG1-CD1 3.75Å; V205-I209 HydrophobicContact CG1-CG1 4.34Å; V205-I209 VanDerWaalsContact O-CG1 3.29Å; V205-I209 WeakPolarHBondContact O-CG1 3.35Å; V205-I209 PolarHBondContact O-N 3.48Å
206	G	95.8	Very high	93.6	Very high	0 Å²	0	20.9 Å²	20.9	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-57.8	-47.3	172.5	0	0	0	0	0	112.5	I202 V203 S204 I208 I209 F210 G355	I202-G206 PolarHBondContact O-N 2.72Å; I202-G206 VanDerWaalsContact O-N 3.16Å; V203-G206 WeakPolarHBondContact O-CA 3.33Å; V203-G206 PolarHBondContact O-N 3.07Å; V203-G206 VanDerWaalsContact O-N 3.12Å; S204-G206 VanDerWaalsContact C-N 3.29Å; S204-G206 PolarHBondContact O-N 2.99Å; G206-I208 VanDerWaalsContact C-N 3.33Å; G206-I208 PolarHBondContact O-N 3.39Å; G206-I209 PolarHBondContact O-N 2.98Å; G206-F210 WeakPolarHBondContact O-CB 3.44Å; G206-F210 PolarHBondContact O-N 3.21Å; G206-G355 WeakPolarHBondContact O-CA 3.46Å
207	V	95.8	Very high	94.1	Very high	2 Å²	2	20.2 Å²	20.2	1%	0.012	11%	0.108	C	C	.	.	H	α-helix	trans	-56.6	-46.5	175.9	163.7	0	0	0	0	111.4	L24 A27 V203 S204 F210 S211 S348 M351	L24-V207 HydrophobicContact CD2-CG1 4.21Å; A27-V207 HydrophobicContact CB-CB 4.04Å; A27-V207 HydrophobicContact CB-CG1 3.57Å; V203-V207 PolarHBondContact O-N 3.04Å; S204-V207 WeakPolarHBondContact O-CB 3.4Å; S204-V207 PolarHBondContact O-N 2.98Å; V207-F210 PolarHBondContact O-N 2.81Å; V207-S211 PolarHBondContact O-N 3.04Å; V207-S348 WeakPolarHBondContact CG2-O 3.36Å; V207-M351 HydrophobicContact CB-CG 4.44Å; V207-M351 HydrophobicContact CB-SD 4.19Å; V207-M351 HydrophobicContact CG1-CG 4.4Å; V207-M351 HydrophobicContact CG1-SD 3.54Å; V207-M351 VanDerWaalsContact CG1-SD 3.54Å; V207-M351 HydrophobicContact CG2-CB 4.11Å; V207-M351 HydrophobicContact CG2-CG 4.22Å; V207-M351 HydrophobicContact CG2-SD 4.31Å
208	I	96.7	Very high	94.4	Very high	1 Å²	1	16.6 Å²	16.6	1%	0.005	9%	0.089	C	C	.	.	H	α-helix	trans	-63.9	-48.1	179.4	-69.9	165.7	0	0	0	111.2	L24 V38 L39 S204 V205 G206 S211 Y212	L24-I208 HydrophobicContact CD2-CG1 4.27Å; V38-I208 HydrophobicContact CB-CD1 4.35Å; V38-I208 HydrophobicContact CG1-CD1 4.19Å; V38-I208 HydrophobicContact CG1-CG2 4.06Å; L39-I208 HydrophobicContact CB-CD1 4.47Å; L39-I208 HydrophobicContact CB-CG2 4.39Å; L39-I208 HydrophobicContact CD1-CG1 4.3Å; L39-I208 HydrophobicContact CD1-CG2 4.05Å; S204-I208 VanDerWaalsContact O-CG1 3.32Å; S204-I208 WeakPolarHBondContact O-CG1 3.31Å; S204-I208 PolarHBondContact O-N 2.93Å; V205-I208 PolarHBondContact O-N 3.23Å; G206-I208 VanDerWaalsContact C-N 3.33Å; G206-I208 PolarHBondContact O-N 3.39Å; I208-S211 WeakPolarHBondContact O-CB 3.03Å; I208-S211 PolarHBondContact O-N 3.23Å; I208-S211 PolarHBondContact O-OG 3.28Å; I208-Y212 PolarHBondContact O-N 2.65Å
209	I	95.9	Very high	94.6	Very high	6 Å²	6	12.1 Å²	12.1	3%	0.031	6%	0.06	C	C	.	.	H	α-helix	trans	-57.7	-51	177.1	-70.6	167.2	0	0	0	109.8	V205 G206 S211 Y212 T213 L364 C397	V205-I209 HydrophobicContact CG1-CD1 3.75Å; V205-I209 HydrophobicContact CG1-CG1 4.34Å; V205-I209 VanDerWaalsContact O-CG1 3.29Å; V205-I209 WeakPolarHBondContact O-CG1 3.35Å; V205-I209 PolarHBondContact O-N 3.48Å; G206-I209 PolarHBondContact O-N 2.98Å; I209-S211 PolarHBondContact O-N 3.21Å; I209-Y212 PolarHBondContact O-N 3.47Å; I209-T213 WeakPolarHBondContact O-CG2 3.28Å; I209-T213 PolarHBondContact O-N 3.29Å; I209-L364 HydrophobicContact CD1-CD1 3.92Å; I209-L364 HydrophobicContact CG1-CD1 4.41Å; I209-C397 HydrophobicContact CD1-CB 4.16Å
210	F	95.2	Very high	94.7	Very high	1 Å²	1	12.3 Å²	12.3	0%	0.004	7%	0.066	C	C	.	.	H	α-helix	trans	-56.3	-39.7	179.2	-175.7	-105.9	0	0	0	111.8	F20 E108 T112 L115 G206 V207 Y212 T213 M351 T354	F20-F210 HydrophobicContact CD1-CD1 4.49Å; F20-F210 AromaticContact CD1-CE1 3.81Å; F20-F210 HydrophobicContact CD1-CE1 3.81Å; F20-F210 HydrophobicContact CD2-CD1 4.23Å; F20-F210 AromaticContact CD2-CE1 3.66Å; F20-F210 HydrophobicContact CD2-CE1 3.66Å; F20-F210 HydrophobicContact CD2-CZ 4.44Å; F20-F210 AromaticContact CE1-CE1 3.8Å; F20-F210 HydrophobicContact CE1-CE1 3.8Å; F20-F210 HydrophobicContact CE1-CZ 4.45Å; F20-F210 AromaticContact CE2-CE1 3.64Å; F20-F210 HydrophobicContact CE2-CE1 3.64Å; F20-F210 HydrophobicContact CE2-CZ 4.02Å; F20-F210 HydrophobicContact CG-CD1 4.18Å; F20-F210 AromaticContact CG-CE1 3.75Å; F20-F210 HydrophobicContact CG-CE1 3.75Å; F20-F210 AromaticContact CZ-CE1 3.72Å; F20-F210 HydrophobicContact CZ-CE1 3.72Å; F20-F210 HydrophobicContact CZ-CZ 4.04Å; E108-F210 HydrophobicContact CG-CE2 4.42Å; T112-F210 HydrophobicContact CG2-CZ 4.29Å; T112-F210 WeakPolarHBondContact OG1-CZ 3.37Å; L115-F210 HydrophobicContact CD1-CD1 4.36Å; L115-F210 HydrophobicContact CD1-CE1 3.46Å; L115-F210 VanDerWaalsContact CD1-CE1 3.46Å; L115-F210 HydrophobicContact CD1-CZ 3.64Å; G206-F210 WeakPolarHBondContact O-CB 3.44Å; G206-F210 PolarHBondContact O-N 3.21Å; V207-F210 PolarHBondContact O-N 2.81Å; F210-Y212 PolarHBondContact O-N 3.24Å; F210-Y212 VanDerWaalsContact O-N 3.14Å; F210-T213 HydrophobicContact CD2-CG2 4.33Å; F210-T213 WeakPolarHBondContact O-CG2 3.29Å; F210-T213 PolarHBondContact O-N 3.44Å; F210-T213 PolarHBondContact O-OG1 2.78Å; F210-M351 HydrophobicContact CB-CG 3.98Å; F210-M351 HydrophobicContact CD1-CB 4.45Å; F210-M351 HydrophobicContact CD1-CG 3.29Å; F210-M351 HydrophobicContact CD1-SD 4.09Å; F210-M351 HydrophobicContact CE1-CG 4.04Å; F210-M351 HydrophobicContact CG-CG 3.92Å; F210-T354 HydrophobicContact CD2-CG2 3.49Å; F210-T354 VanDerWaalsContact CD2-CG2 3.49Å; F210-T354 HydrophobicContact CE2-CG2 3.25Å; F210-T354 HydrophobicContact CZ-CG2 4.13Å
211	S	95.7	Very high	94.8	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-61.2	-26.1	179.8	88.1	0	0	0	0	112.6	I16 V207 I208 I209 K246	I16-S211 CarbonylContact C-O 3.45Å; I16-S211 WeakPolarHBondContact CA-O 3.16Å; V207-S211 PolarHBondContact O-N 3.04Å; I208-S211 WeakPolarHBondContact O-CB 3.03Å; I208-S211 PolarHBondContact O-N 3.23Å; I208-S211 PolarHBondContact O-OG 3.28Å; I209-S211 PolarHBondContact O-N 3.21Å; S211-K246 PolarHBondContact O-NZ 3.31Å; S211-K246 PolarHBondContact OG-NZ 3Å
212	Y	95.8	Very high	94.9	Very high	0 Å²	0	8 Å²	8	0%	0	5%	0.046	C	C	.	.	T	Hydrogen-bonded Turn	trans	-100.6	9	-178.9	-77.1	-74.2	0	0	0	114	L39 A43 C46 I208 I209 F210 S214 A242 C243 K246	L39-Y212 HydrophobicContact CD1-CE2 3.87Å; L39-Y212 WeakPolarHBondContact O-CE2 3.41Å; A43-Y212 HydrophobicContact CB-CD1 4.26Å; A43-Y212 HydrophobicContact CB-CE1 3.64Å; A43-Y212 HydrophobicContact CB-CE2 4.32Å; C46-Y212 VanDerWaalsContact SG-CB 3.56Å; I208-Y212 PolarHBondContact O-N 2.65Å; I209-Y212 PolarHBondContact O-N 3.47Å; F210-Y212 PolarHBondContact O-N 3.24Å; F210-Y212 VanDerWaalsContact O-N 3.14Å; Y212-S214 PolarHBondContact O-N 3.15Å; Y212-A242 HydrophobicContact CE1-CB 4.18Å; Y212-C243 WeakPolarHBondContact OH-CA 3.09Å; Y212-K246 HydrophobicContact CE1-CD 3.92Å; Y212-K246 HydrophobicContact CE2-CD 4.1Å; Y212-K246 WeakPolarHBondContact OH-CD 3.41Å
213	T	94	Very high	94.8	Very high	10 Å²	10	7.5 Å²	7.5	6%	0.061	5%	0.048	C	C	.	.			trans	-70.7	125.7	-178	71.1	0	0	0	0	111	E108 I209 F210 T363	E108-T213 VanDerWaalsContact OE1-CB 3.26Å; E108-T213 WeakPolarHBondContact OE1-CB 3.29Å; E108-T213 PolarHBondContact OE1-OG1 3.47Å; I209-T213 WeakPolarHBondContact O-CG2 3.28Å; I209-T213 PolarHBondContact O-N 3.29Å; F210-T213 HydrophobicContact CD2-CG2 4.33Å; F210-T213 WeakPolarHBondContact O-CG2 3.29Å; F210-T213 PolarHBondContact O-N 3.44Å; F210-T213 PolarHBondContact O-OG1 2.78Å; T213-T363 HydrophobicContact CG2-CG2 3.57Å
214	S	95	Very high	94.7	Very high	1 Å²	1	9.5 Å²	9.5	1%	0.007	6%	0.058	C	C	.	.			trans	-145.5	-8.6	174.1	58.9	0	0	0	0	113.2	Y212 I216 F217 L218	Y212-S214 PolarHBondContact O-N 3.15Å; S214-I216 PolarHBondContact O-N 3.46Å; S214-I216 VanDerWaalsContact O-N 3.14Å; S214-F217 WeakPolarHBondContact O-CB 3.21Å; S214-F217 PolarHBondContact O-N 2.94Å; S214-L218 WeakPolarHBondContact O-CG 3.34Å; S214-L218 PolarHBondContact O-N 3.47Å
215	Q	95.5	Very high	94.6	Very high	1 Å²	1	9.9 Å²	9.9	1%	0.005	6%	0.06	C	C	.	.	T	Hydrogen-bonded Turn	trans	-60.5	-30.4	-168.6	-74.3	78.8	-8.3	0	0	112.5	C46 T49 L53 Y78 F217 L218 P219 T363	C46-Q215 PolarHBondContact O-NE2 3.45Å; T49-Q215 PolarHBondContact OG1-NE2 2.66Å; T49-Q215 VanDerWaalsContact OG1-NE2 3.11Å; L53-Q215 HydrophobicContact CD2-CB 3.95Å; L53-Q215 HydrophobicContact CD2-CG 4.39Å; L53-Q215 WeakPolarHBondContact CD2-O 3.32Å; Y78-Q215 HydrophobicContact CE2-CB 4.31Å; Q215-F217 VanDerWaalsContact C-N 3.26Å; Q215-F217 PolarHBondContact O-N 3.46Å; Q215-L218 HydrophobicContact CG-CD1 4.45Å; Q215-L218 PolarHBondContact O-N 3Å; Q215-P219 VanDerWaalsContact O-CD 3.23Å; Q215-P219 WeakPolarHBondContact O-CD 3.47Å; Q215-T363 HydrophobicContact CB-CG2 4.33Å; Q215-T363 VanDerWaalsContact CD-CB 3.46Å; Q215-T363 HydrophobicContact CG-CG2 4.18Å
216	I	95.1	Very high	94.5	Very high	6 Å²	6	15 Å²	15	3%	0.031	8%	0.083	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.4	-37.1	174.7	-62.4	175	0	0	0	111.3	Q105 E108 L109 S214 M362	Q105-I216 HydrophobicContact CB-CD1 4.48Å; Q105-I216 HydrophobicContact CB-CG2 4.49Å; Q105-I216 HydrophobicContact CG-CD1 4.41Å; Q105-I216 HydrophobicContact CG-CG1 4.17Å; Q105-I216 HydrophobicContact CG-CG2 4.31Å; E108-I216 HydrophobicContact CB-CD1 3.79Å; E108-I216 HydrophobicContact CG-CD1 3.88Å; L109-I216 HydrophobicContact CD1-CG2 3.83Å; L109-I216 HydrophobicContact CD2-CD1 4.28Å; L109-I216 HydrophobicContact CD2-CG2 4.18Å; L109-I216 HydrophobicContact CG-CD1 4.13Å; L109-I216 HydrophobicContact CG-CG2 4.22Å; S214-I216 PolarHBondContact O-N 3.46Å; S214-I216 VanDerWaalsContact O-N 3.14Å; I216-M362 HydrophobicContact CG1-CE 4.2Å
217	F	94.1	Very high	94.4	Very high	24 Å²	24	18.8 Å²	18.8	11%	0.105	10%	0.104	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.8	-23.4	-176.9	-52.9	-75.9	0	0	0	112.7	A15 L109 S214 Q215 P220 L221 L291 P292 A295	A15-F217 HydrophobicContact CB-CD2 3.69Å; A15-F217 HydrophobicContact CB-CE2 3.66Å; L109-F217 HydrophobicContact CD2-CE1 3.96Å; L109-F217 HydrophobicContact CD2-CE2 4.27Å; L109-F217 HydrophobicContact CD2-CZ 3.49Å; L109-F217 VanDerWaalsContact CD2-CZ 3.49Å; S214-F217 WeakPolarHBondContact O-CB 3.21Å; S214-F217 PolarHBondContact O-N 2.94Å; Q215-F217 VanDerWaalsContact C-N 3.26Å; Q215-F217 PolarHBondContact O-N 3.46Å; F217-P220 VanDerWaalsContact O-CD 3.28Å; F217-P220 WeakPolarHBondContact O-CD 3.2Å; F217-P220 WeakPolarHBondContact O-CG 3.34Å; F217-L221 WeakPolarHBondContact O-CB 3.31Å; F217-L221 PolarHBondContact O-N 2.9Å; F217-L291 HydrophobicContact CD1-CD1 4.25Å; F217-L291 HydrophobicContact CD1-CG 4.31Å; F217-L291 HydrophobicContact CE1-CD1 4.24Å; F217-L291 HydrophobicContact CE1-CG 3.89Å; F217-L291 HydrophobicContact CZ-CG 4.25Å; F217-P292 HydrophobicContact CZ-CB 4.34Å; F217-A295 HydrophobicContact CD1-CB 3.95Å; F217-A295 HydrophobicContact CE1-CB 3.52Å
218	L	95.7	Very high	94.3	Very high	0 Å²	0	23.5 Å²	23.5	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-62.7	-48.2	-169.3	-55.9	179.5	0	0	0	114.1	V12 V54 S214 Q215 L221 E222 F231 L235	V12-L218 HydrophobicContact CG2-CD2 4.04Å; V54-L218 HydrophobicContact CG2-CB 4.08Å; S214-L218 WeakPolarHBondContact O-CG 3.34Å; S214-L218 PolarHBondContact O-N 3.47Å; Q215-L218 HydrophobicContact CG-CD1 4.45Å; Q215-L218 PolarHBondContact O-N 3Å; L218-L221 PolarHBondContact O-N 3.39Å; L218-E222 WeakPolarHBondContact O-CB 3.26Å; L218-E222 PolarHBondContact O-N 3.06Å; L218-F231 HydrophobicContact CB-CE2 4.42Å; L218-F231 HydrophobicContact CB-CZ 4.08Å; L218-F231 HydrophobicContact CD1-CZ 4.29Å; L218-F231 HydrophobicContact CD2-CE2 4.21Å; L218-F231 HydrophobicContact CD2-CZ 4.02Å; L218-F231 HydrophobicContact CG-CZ 4.34Å; L218-L235 HydrophobicContact CD1-CD1 4.24Å; L218-L235 HydrophobicContact CD1-CD2 4.28Å; L218-L235 HydrophobicContact CD2-CD1 3.69Å
219	P	94.7	Very high	94.2	Very high	0 Å²	0	26.5 Å²	26.5	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-60.6	-50.5	179.7	-22.8	33.3	0	0	0	115.4	L53 L57 R73 Y78 Q215 L221 G223	L53-P219 HydrophobicContact CD2-CG 4.09Å; L53-P219 HydrophobicContact CG-CG 4.38Å; L57-P219 HydrophobicContact CD1-CB 3.97Å; L57-P219 HydrophobicContact CD2-CB 4.15Å; R73-P219 PolarHBondContact NH2-O 2.76Å; Y78-P219 HydrophobicContact CD2-CG 4.48Å; Q215-P219 VanDerWaalsContact O-CD 3.23Å; Q215-P219 WeakPolarHBondContact O-CD 3.47Å; P219-L221 VanDerWaalsContact C-N 3.35Å; P219-G223 PolarHBondContact O-N 2.81Å
220	P	92.3	Very high	94.2	Very high	65 Å²	65	30.5 Å²	30.5	42%	0.422	17%	0.171	S	C	.	.	H	α-helix	trans	-68.4	-34.6	177.2	26.1	-33.2	0	0	0	112	F217 G223 I224	F217-P220 VanDerWaalsContact O-CD 3.28Å; F217-P220 WeakPolarHBondContact O-CD 3.2Å; F217-P220 WeakPolarHBondContact O-CG 3.34Å; P220-G223 VanDerWaalsContact O-CA 3.22Å; P220-G223 WeakPolarHBondContact O-CA 3.12Å; P220-G223 PolarHBondContact O-N 3.4Å; P220-I224 PolarHBondContact O-N 2.76Å
221	L	92.9	Very high	94.2	Very high	8 Å²	8	30.6 Å²	30.6	4%	0.042	17%	0.171	C	C	.	.	H	α-helix	trans	-64.7	-48.6	178.8	-171	74.1	0	0	0	111.8	I3 A8 N11 V12 F217 L218 P219 G223 I224 M225 M234	I3-L221 HydrophobicContact CD1-CD1 3.52Å; I3-L221 HydrophobicContact CD1-CG 4.41Å; A8-L221 HydrophobicContact CB-CD1 4.16Å; A8-L221 HydrophobicContact CB-CD2 3.99Å; A8-L221 HydrophobicContact CB-CG 3.99Å; N11-L221 HydrophobicContact CB-CD1 3.97Å; N11-L221 HydrophobicContact CB-CD2 4.45Å; V12-L221 HydrophobicContact CG2-CD2 3.48Å; V12-L221 VanDerWaalsContact CG2-CD2 3.48Å; F217-L221 WeakPolarHBondContact O-CB 3.31Å; F217-L221 PolarHBondContact O-N 2.9Å; L218-L221 PolarHBondContact O-N 3.39Å; P219-L221 VanDerWaalsContact C-N 3.35Å; L221-G223 PolarHBondContact O-N 3.48Å; L221-I224 WeakPolarHBondContact O-CG1 3.36Å; L221-I224 PolarHBondContact O-N 3.44Å; L221-I224 VanDerWaalsContact O-N 3.15Å; L221-M225 WeakPolarHBondContact O-CG 3.37Å; L221-M225 PolarHBondContact O-N 2.98Å; L221-M234 HydrophobicContact CD2-CE 4.28Å
222	E	95	Very high	94.2	Very high	2 Å²	2	34.5 Å²	34.5	1%	0.009	19%	0.192	C	C	.	.	H	α-helix	trans	-64.6	-30.5	174.5	-166.2	-85.2	174	0	0	111.4	V54 Y58 R73 L218 I224 M225 R228 F231	V54-E222 HydrophobicContact CG1-CG 4.01Å; Y58-E222 PolarHBondContact OH-OE1 3.23Å; R73-E222 IonicContact CZ-OE2 3.88Å; R73-E222 IonicContact NE-OE2 2.67Å; R73-E222 IonicContact NH1-OE2 3.41Å; R73-E222 PolarHBondContact NH1-OE2 2.96Å; R73-E222 IonicContact NH2-OE2 3.49Å; L218-E222 WeakPolarHBondContact O-CB 3.26Å; L218-E222 PolarHBondContact O-N 3.06Å; E222-I224 PolarHBondContact O-N 3.48Å; E222-M225 PolarHBondContact O-N 3.45Å; E222-R228 HydrophobicContact CG-CG 4.46Å; E222-R228 PolarHBondContact O-NE 3.46Å; E222-R228 WeakPolarHBondContact OE1-CB 3.36Å; E222-R228 VanDerWaalsContact OE1-CD 3.24Å; E222-R228 WeakPolarHBondContact OE1-CD 3.28Å; E222-R228 VanDerWaalsContact OE1-CG 3.31Å; E222-R228 WeakPolarHBondContact OE1-CG 3.3Å; E222-F231 HydrophobicContact CB-CD2 3.79Å; E222-F231 HydrophobicContact CB-CE2 3.99Å; E222-F231 HydrophobicContact CB-CG 4.48Å; E222-F231 HydrophobicContact CG-CB 4.17Å; E222-F231 HydrophobicContact CG-CD2 3.68Å; E222-F231 HydrophobicContact CG-CE2 4.28Å; E222-F231 HydrophobicContact CG-CG 3.89Å
223	G	92	Very high	94.3	Very high	20 Å²	20	38.6 Å²	38.6	21%	0.206	22%	0.217	C	C	.	.	H	α-helix	trans	-30.2	-56.3	160.1	0	0	0	0	0	115.3	P219 P220 L221 R228	P219-G223 PolarHBondContact O-N 2.81Å; P220-G223 VanDerWaalsContact O-CA 3.22Å; P220-G223 WeakPolarHBondContact O-CA 3.12Å; P220-G223 PolarHBondContact O-N 3.4Å; L221-G223 PolarHBondContact O-N 3.48Å; G223-R228 PolarHBondContact O-NH2 2.82Å
224	I	91.1	Very high	94.4	Very high	44 Å²	44	38.5 Å²	38.5	23%	0.226	22%	0.216	C	C	.	.	H	α-helix	trans	-110.5	1.8	-161.4	60.2	163.6	0	0	0	113	T2 I3 L155 P220 L221 E222	T2-I224 CarbonylContact C-O 3.58Å; T2-I224 WeakPolarHBondContact CA-O 3.45Å; T2-I224 WeakPolarHBondContact CB-O 3.27Å; I3-I224 HydrophobicContact CD1-CD1 3.65Å; I3-I224 HydrophobicContact CD1-CG1 3.95Å; I3-I224 HydrophobicContact CG1-CD1 3.86Å; I3-I224 HydrophobicContact CG1-CG1 3.89Å; I3-I224 HydrophobicContact CG2-CD1 4.17Å; I3-I224 PolarHBondContact N-O 2.86Å; L155-I224 HydrophobicContact CB-CD1 4.33Å; L155-I224 HydrophobicContact CD1-CD1 3.43Å; L155-I224 VanDerWaalsContact CD1-CD1 3.43Å; P220-I224 PolarHBondContact O-N 2.76Å; L221-I224 WeakPolarHBondContact O-CG1 3.36Å; L221-I224 PolarHBondContact O-N 3.44Å; L221-I224 VanDerWaalsContact O-N 3.15Å; E222-I224 PolarHBondContact O-N 3.48Å
225	M	93.6	Very high	94.6	Very high	7 Å²	7	38.4 Å²	38.4	3%	0.034	22%	0.216	C	C	.	.	B	Isolated β-bridge	trans	-66.9	135.2	174.6	-76.7	176	63.8	0	0	111	I3 A5 A8 L221 E222 D227 R228 Q230 F231 M234	I3-M225 HydrophobicContact CG1-CG 4.48Å; I3-M225 WeakPolarHBondContact O-CA 3.37Å; A5-M225 HydrophobicContact CB-CE 3.99Å; A8-M225 HydrophobicContact CB-CE 4.47Å; A8-M225 HydrophobicContact CB-CG 3.94Å; A8-M225 HydrophobicContact CB-SD 3.87Å; L221-M225 WeakPolarHBondContact O-CG 3.37Å; L221-M225 PolarHBondContact O-N 2.98Å; E222-M225 PolarHBondContact O-N 3.45Å; M225-D227 WeakPolarHBondContact CE-O 3.5Å; M225-R228 HydrophobicContact CB-CG 4.46Å; M225-Q230 HydrophobicContact CE-CB 4.46Å; M225-F231 HydrophobicContact CE-CB 4.3Å; M225-F231 HydrophobicContact SD-CB 4.4Å; M225-F231 HydrophobicContact SD-CD2 3.91Å; M225-M234 HydrophobicContact CE-CE 4.35Å; M225-M234 HydrophobicContact SD-CE 3.91Å
226	E	93.4	Very high	94.7	Very high	118 Å²	118	39.4 Å²	39.4	55%	0.551	23%	0.226	S	C	*	.	S	Bend	trans	-60.1	-46.6	175.4	-70.7	177	175.1	0	0	111.8	T2 I3	T2-E226 HydrophobicContact CG2-CG 4.45Å; T2-E226 WeakPolarHBondContact OG1-CG 3.37Å; T2-E226 PolarHBondContact OG1-OE1 3.13Å; I3-E226 PolarHBondContact O-N 3.37Å
227	D	93.4	Very high	94.7	Very high	79 Å²	79	47.6 Å²	47.6	42%	0.422	26%	0.257	S	S	.	.			trans	-121.5	101.3	174.5	-179	5.2	0	0	0	110.3	M225 G229 Q230	M225-D227 WeakPolarHBondContact CE-O 3.5Å; D227-G229 PolarHBondContact O-N 3.46Å; D227-G229 WeakPolarHBondContact OD1-CA 3.22Å; D227-G229 PolarHBondContact OD1-N 3.16Å; D227-Q230 HydrophobicContact CB-CG 4.35Å; D227-Q230 PolarHBondContact O-N 3.41Å; D227-Q230 WeakPolarHBondContact OD2-CG 3.44Å; D227-Q230 PolarHBondContact OD2-NE2 2.82Å
228	R	93.9	Very high	94.8	Very high	100 Å²	100	46.8 Å²	46.8	38%	0.377	25%	0.254	S	S	.	.	G	3₁₀ helix	trans	-67.4	-21.8	178	-68.2	174.7	-177.2	162.1	5.3	113	Y58 E222 G223 M225 Q230 F231	Y58-R228 WeakPolarHBondContact OH-CD 3.34Å; E222-R228 HydrophobicContact CG-CG 4.46Å; E222-R228 PolarHBondContact O-NE 3.46Å; E222-R228 WeakPolarHBondContact OE1-CB 3.36Å; E222-R228 VanDerWaalsContact OE1-CD 3.24Å; E222-R228 WeakPolarHBondContact OE1-CD 3.28Å; E222-R228 VanDerWaalsContact OE1-CG 3.31Å; E222-R228 WeakPolarHBondContact OE1-CG 3.3Å; G223-R228 PolarHBondContact O-NH2 2.82Å; M225-R228 HydrophobicContact CB-CG 4.46Å; R228-Q230 PolarHBondContact O-N 2.91Å; R228-F231 VanDerWaalsContact O-CB 3.27Å; R228-F231 WeakPolarHBondContact O-CB 3.44Å; R228-F231 PolarHBondContact O-N 2.7Å; R228-F231 VanDerWaalsContact O-N 3.11Å
229	G	93.3	Very high	94.9	Very high	64 Å²	64	47 Å²	47	66%	0.66	26%	0.255	S	S	*	.	G	3₁₀ helix	trans	-63	-21.2	177	0	0	0	0	0	113.2	D227 F231	D227-G229 PolarHBondContact O-N 3.46Å; D227-G229 WeakPolarHBondContact OD1-CA 3.22Å; D227-G229 PolarHBondContact OD1-N 3.16Å; G229-F231 VanDerWaalsContact C-N 3.35Å
230	Q	95.7	Very high	95	Very high	90 Å²	90	48.6 Å²	48.6	42%	0.421	27%	0.271	S	S	.	.	G	3₁₀ helix	trans	-85	-5.6	178.5	-62.6	177.9	28.4	0	0	113.6	A5 M225 D227 R228 D232 T233 M234	A5-Q230 HydrophobicContact CB-CB 3.94Å; M225-Q230 HydrophobicContact CE-CB 4.46Å; D227-Q230 HydrophobicContact CB-CG 4.35Å; D227-Q230 PolarHBondContact O-N 3.41Å; D227-Q230 WeakPolarHBondContact OD2-CG 3.44Å; D227-Q230 PolarHBondContact OD2-NE2 2.82Å; R228-Q230 PolarHBondContact O-N 2.91Å; Q230-D232 PolarHBondContact O-N 3.09Å; Q230-T233 PolarHBondContact O-N 3.41Å; Q230-M234 WeakPolarHBondContact O-CB 3.32Å; Q230-M234 PolarHBondContact O-N 2.93Å
231	F	96.3	Very high	95.1	Very high	4 Å²	4	49 Å²	49	2%	0.018	27%	0.272	C	S	.	.	H	α-helix	trans	-58.2	-49.7	-174.4	178.3	-93.5	0	0	0	112.9	V54 L218 E222 M225 R228 G229 T233 M234 L235	V54-F231 HydrophobicContact CB-CD1 4.29Å; V54-F231 HydrophobicContact CB-CE1 3.76Å; V54-F231 HydrophobicContact CB-CZ 4.22Å; V54-F231 HydrophobicContact CG1-CD1 4.01Å; V54-F231 HydrophobicContact CG1-CE1 3.99Å; V54-F231 HydrophobicContact CG2-CD1 4.27Å; V54-F231 HydrophobicContact CG2-CE1 3.46Å; V54-F231 VanDerWaalsContact CG2-CE1 3.46Å; V54-F231 HydrophobicContact CG2-CE2 4.12Å; V54-F231 HydrophobicContact CG2-CZ 3.38Å; L218-F231 HydrophobicContact CB-CE2 4.42Å; L218-F231 HydrophobicContact CB-CZ 4.08Å; L218-F231 HydrophobicContact CD1-CZ 4.29Å; L218-F231 HydrophobicContact CD2-CE2 4.21Å; L218-F231 HydrophobicContact CD2-CZ 4.02Å; L218-F231 HydrophobicContact CG-CZ 4.34Å; E222-F231 HydrophobicContact CB-CD2 3.79Å; E222-F231 HydrophobicContact CB-CE2 3.99Å; E222-F231 HydrophobicContact CB-CG 4.48Å; E222-F231 HydrophobicContact CG-CB 4.17Å; E222-F231 HydrophobicContact CG-CD2 3.68Å; E222-F231 HydrophobicContact CG-CE2 4.28Å; E222-F231 HydrophobicContact CG-CG 3.89Å; M225-F231 HydrophobicContact CE-CB 4.3Å; M225-F231 HydrophobicContact SD-CB 4.4Å; M225-F231 HydrophobicContact SD-CD2 3.91Å; R228-F231 VanDerWaalsContact O-CB 3.27Å; R228-F231 WeakPolarHBondContact O-CB 3.44Å; R228-F231 PolarHBondContact O-N 2.7Å; R228-F231 VanDerWaalsContact O-N 3.11Å; G229-F231 VanDerWaalsContact C-N 3.35Å; F231-T233 VanDerWaalsContact C-N 3.31Å; F231-T233 PolarHBondContact O-N 3.04Å; F231-M234 HydrophobicContact CD2-CE 3.78Å; F231-M234 HydrophobicContact CE2-CE 4Å; F231-M234 PolarHBondContact O-N 3.26Å; F231-L235 HydrophobicContact CE1-CB 4.45Å; F231-L235 HydrophobicContact CE1-CD2 3.9Å; F231-L235 HydrophobicContact CZ-CD1 4.44Å; F231-L235 HydrophobicContact CZ-CD2 4.02Å; F231-L235 WeakPolarHBondContact O-CB 3.17Å; F231-L235 PolarHBondContact O-N 3.12Å
232	D	96.5	Very high	95.2	Very high	81 Å²	81	48.7 Å²	48.7	43%	0.433	27%	0.271	S	S	.	.	H	α-helix	trans	-63.7	-37.8	-176.8	-77.8	-10	0	0	0	112.5	R51 Q230 G236	R51-D232 PolarHBondContact NH2-O 2.85Å; Q230-D232 PolarHBondContact O-N 3.09Å; D232-G236 PolarHBondContact O-N 3.3Å
233	T	96.9	Very high	95.3	Very high	86 Å²	86	49.7 Å²	49.7	53%	0.528	28%	0.277	S	S	.	.	H	α-helix	trans	-67.9	-47.1	176.1	-58.8	0	0	0	0	110.6	Q230 F231 L235 G236 W237	Q230-T233 PolarHBondContact O-N 3.41Å; F231-T233 VanDerWaalsContact C-N 3.31Å; F231-T233 PolarHBondContact O-N 3.04Å; T233-L235 PolarHBondContact O-N 3.44Å; T233-G236 PolarHBondContact O-N 3.42Å; T233-W237 VanDerWaalsContact O-CD1 3.25Å; T233-W237 PolarHBondContact O-N 2.9Å
234	M	96.9	Very high	95.5	Very high	8 Å²	8	54.1 Å²	54.1	4%	0.039	30%	0.295	C	S	.	.	H	α-helix	trans	-58.4	-47.1	176.1	174.9	-89	-70.5	0	0	111.8	A8 S9 V12 L221 M225 Q230 F231 G236 W237 T238	A8-M234 HydrophobicContact CB-CE 3.8Å; S9-M234 WeakPolarHBondContact OG-CG 3.44Å; V12-M234 HydrophobicContact CB-SD 4.3Å; V12-M234 HydrophobicContact CG2-CE 4.23Å; V12-M234 HydrophobicContact CG2-SD 3.83Å; L221-M234 HydrophobicContact CD2-CE 4.28Å; M225-M234 HydrophobicContact CE-CE 4.35Å; M225-M234 HydrophobicContact SD-CE 3.91Å; Q230-M234 WeakPolarHBondContact O-CB 3.32Å; Q230-M234 PolarHBondContact O-N 2.93Å; F231-M234 HydrophobicContact CD2-CE 3.78Å; F231-M234 HydrophobicContact CE2-CE 4Å; F231-M234 PolarHBondContact O-N 3.26Å; M234-G236 VanDerWaalsContact C-N 3.32Å; M234-G236 PolarHBondContact O-N 3.39Å; M234-W237 PolarHBondContact O-N 3.21Å; M234-T238 HydrophobicContact CG-CG2 4.48Å; M234-T238 WeakPolarHBondContact O-CG2 3.36Å; M234-T238 PolarHBondContact O-N 3.36Å; M234-T238 PolarHBondContact O-OG1 2.84Å; M234-T238 HydrophobicContact SD-CG2 4.2Å
235	L	97.4	Very high	95.6	Very high	0 Å²	0	54 Å²	54	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-64.5	-39.3	-179.6	-165.4	68.4	0	0	0	111.6	V12 R51 L218 F231 T233 T238 H239	V12-L235 HydrophobicContact CG1-CD1 4.11Å; R51-L235 HydrophobicContact CG-CD2 3.91Å; L218-L235 HydrophobicContact CD1-CD1 4.24Å; L218-L235 HydrophobicContact CD1-CD2 4.28Å; L218-L235 HydrophobicContact CD2-CD1 3.69Å; F231-L235 HydrophobicContact CE1-CB 4.45Å; F231-L235 HydrophobicContact CE1-CD2 3.9Å; F231-L235 HydrophobicContact CZ-CD1 4.44Å; F231-L235 HydrophobicContact CZ-CD2 4.02Å; F231-L235 WeakPolarHBondContact O-CB 3.17Å; F231-L235 PolarHBondContact O-N 3.12Å; T233-L235 PolarHBondContact O-N 3.44Å; L235-T238 WeakPolarHBondContact CA-OG1 2.99Å; L235-T238 PolarHBondContact O-OG1 3.02Å; L235-H239 VanDerWaalsContact CD1-CE1 3.43Å; L235-H239 WeakPolarHBondContact CD1-CE1 3.48Å; L235-H239 WeakPolarHBondContact O-CB 3.37Å; L235-H239 PolarHBondContact O-N 3.22Å; L235-H239 VanDerWaalsContact O-N 3.1Å; L235-H239 PolarHBondContact O-ND1 3.23Å
236	G	97.7	Very high	95.7	Very high	21 Å²	21	53.6 Å²	53.6	22%	0.216	29%	0.292	C	S	.	.	H	α-helix	trans	-63.2	-45.8	175.9	0	0	0	0	0	112.8	N47 D232 T233 M234 G240	N47-G236 PolarHBondContact OD1-N 3.43Å; D232-G236 PolarHBondContact O-N 3.3Å; T233-G236 PolarHBondContact O-N 3.42Å; M234-G236 VanDerWaalsContact C-N 3.32Å; M234-G236 PolarHBondContact O-N 3.39Å; G236-G240 PolarHBondContact O-N 2.72Å
237	W	96.5	Very high	95.8	Very high	179 Å²	179	49.2 Å²	49.2	68%	0.678	27%	0.274	S	S	*	.	H	α-helix	trans	-64	-47.3	177.5	-85.4	110.3	0	0	0	112.5	T233 M234 H239 G240 V241	T233-W237 VanDerWaalsContact O-CD1 3.25Å; T233-W237 PolarHBondContact O-N 2.9Å; M234-W237 PolarHBondContact O-N 3.21Å; W237-H239 PolarHBondContact O-N 2.89Å; W237-G240 PolarHBondContact O-N 2.93Å; W237-V241 HydrophobicContact CE3-CG2 4.34Å; W237-V241 WeakPolarHBondContact O-CB 3.17Å; W237-V241 WeakPolarHBondContact O-CG2 3.33Å; W237-V241 PolarHBondContact O-N 3.08Å
238	T	96.1	Very high	95.8	Very high	7 Å²	7	48 Å²	48	4%	0.043	27%	0.269	C	S	.	.	H	α-helix	trans	-61	-45.3	-179.2	50.2	0	0	0	0	111.8	S9 V12 I16 M234 L235 A242	S9-T238 WeakPolarHBondContact O-CG2 3.23Å; V12-T238 HydrophobicContact CB-CG2 4.19Å; V12-T238 HydrophobicContact CG1-CG2 4.23Å; V12-T238 WeakPolarHBondContact CG1-OG1 3.29Å; I16-T238 WeakPolarHBondContact CD1-O 3.41Å; M234-T238 HydrophobicContact CG-CG2 4.48Å; M234-T238 WeakPolarHBondContact O-CG2 3.36Å; M234-T238 PolarHBondContact O-N 3.36Å; M234-T238 PolarHBondContact O-OG1 2.84Å; M234-T238 HydrophobicContact SD-CG2 4.2Å; L235-T238 WeakPolarHBondContact CA-OG1 2.99Å; L235-T238 PolarHBondContact O-OG1 3.02Å; T238-A242 VanDerWaalsContact O-CB 3.23Å; T238-A242 WeakPolarHBondContact O-CB 3.19Å; T238-A242 PolarHBondContact O-N 3.34Å
239	H	97.1	Very high	95.8	Very high	4 Å²	4	43.5 Å²	43.5	2%	0.019	25%	0.252	C	S	.	.	H	α-helix	trans	-70.5	-38.3	177.2	-75.2	71.6	0	0	0	112.9	N47 L235 W237 A242 C243	N47-H239 HydrophobicContact CB-CB 3.91Å; L235-H239 VanDerWaalsContact CD1-CE1 3.43Å; L235-H239 WeakPolarHBondContact CD1-CE1 3.48Å; L235-H239 WeakPolarHBondContact O-CB 3.37Å; L235-H239 PolarHBondContact O-N 3.22Å; L235-H239 VanDerWaalsContact O-N 3.1Å; L235-H239 PolarHBondContact O-ND1 3.23Å; W237-H239 PolarHBondContact O-N 2.89Å; H239-A242 PolarHBondContact O-N 3.41Å; H239-C243 VanDerWaalsContact O-CB 3.3Å; H239-C243 WeakPolarHBondContact O-CB 2.98Å; H239-C243 PolarHBondContact O-N 3.44Å
240	G	97	Very high	95.9	Very high	33 Å²	33	40.4 Å²	40.4	34%	0.34	22%	0.221	S	C	.	.	H	α-helix	trans	-63.1	-48.3	177.1	0	0	0	0	0	112.3	G236 W237 C243 I244	G236-G240 PolarHBondContact O-N 2.72Å; W237-G240 PolarHBondContact O-N 2.93Å; G240-C243 WeakPolarHBondContact O-CB 3.39Å; G240-C243 PolarHBondContact O-N 3.46Å; G240-I244 WeakPolarHBondContact O-CG1 3.22Å; G240-I244 PolarHBondContact O-N 3.39Å; G240-I244 VanDerWaalsContact O-N 3.1Å
241	V	95	Very high	95.8	Very high	74 Å²	74	37.8 Å²	37.8	45%	0.448	21%	0.209	S	C	.	.	H	α-helix	trans	-63.3	-44.8	176.2	173.1	0	0	0	0	110.7	W237 C243 I244 M245	W237-V241 HydrophobicContact CE3-CG2 4.34Å; W237-V241 WeakPolarHBondContact O-CB 3.17Å; W237-V241 WeakPolarHBondContact O-CG2 3.33Å; W237-V241 PolarHBondContact O-N 3.08Å; V241-C243 VanDerWaalsContact C-N 3.32Å; V241-C243 PolarHBondContact O-N 2.67Å; V241-I244 PolarHBondContact O-N 3.28Å; V241-M245 HydrophobicContact CG1-CG 4.19Å; V241-M245 WeakPolarHBondContact O-CB 3.46Å; V241-M245 VanDerWaalsContact O-CG 3.31Å; V241-M245 WeakPolarHBondContact O-CG 3.45Å; V241-M245 PolarHBondContact O-N 3.18Å
242	A	95.1	Very high	95.8	Very high	2 Å²	2	38.5 Å²	38.5	2%	0.017	21%	0.213	C	C	.	.	H	α-helix	trans	-60.9	-39.8	176.4	0	0	0	0	0	112.3	I16 Y212 T238 H239 K246	I16-A242 HydrophobicContact CD1-CB 3.46Å; I16-A242 VanDerWaalsContact CD1-CB 3.46Å; I16-A242 HydrophobicContact CG1-CB 3.9Å; Y212-A242 HydrophobicContact CE1-CB 4.18Å; T238-A242 VanDerWaalsContact O-CB 3.23Å; T238-A242 WeakPolarHBondContact O-CB 3.19Å; T238-A242 PolarHBondContact O-N 3.34Å; H239-A242 PolarHBondContact O-N 3.41Å; A242-K246 WeakPolarHBondContact O-CB 3.23Å; A242-K246 VanDerWaalsContact O-CG 3.23Å; A242-K246 WeakPolarHBondContact O-CG 3.1Å; A242-K246 PolarHBondContact O-N 3.4Å
243	C	96.8	Very high	95.6	Very high	22 Å²	22	34.7 Å²	34.7	15%	0.149	19%	0.193	C	C	.	.	H	α-helix	trans	-57.4	-52.9	174.2	-171	0	0	0	0	112	A43 Y212 H239 G240 V241 M245 T247	A43-C243 HydrophobicContact CB-CB 3.67Å; Y212-C243 WeakPolarHBondContact OH-CA 3.09Å; H239-C243 VanDerWaalsContact O-CB 3.3Å; H239-C243 WeakPolarHBondContact O-CB 2.98Å; H239-C243 PolarHBondContact O-N 3.44Å; G240-C243 WeakPolarHBondContact O-CB 3.39Å; G240-C243 PolarHBondContact O-N 3.46Å; V241-C243 VanDerWaalsContact C-N 3.32Å; V241-C243 PolarHBondContact O-N 2.67Å; C243-M245 PolarHBondContact O-N 2.88Å; C243-T247 WeakPolarHBondContact O-CB 3.29Å; C243-T247 PolarHBondContact O-N 3.47Å; C243-T247 PolarHBondContact O-OG1 3.11Å
244	I	95.8	Very high	95.4	Very high	113 Å²	113	30.6 Å²	30.6	58%	0.579	17%	0.168	S	C	*	.	H	α-helix	trans	-61.4	-48.5	-179.2	-65.7	166.9	0	0	0	110.3	G240 V241 T248	G240-I244 WeakPolarHBondContact O-CG1 3.22Å; G240-I244 PolarHBondContact O-N 3.39Å; G240-I244 VanDerWaalsContact O-N 3.1Å; V241-I244 PolarHBondContact O-N 3.28Å; I244-T248 VanDerWaalsContact O-CB 3.28Å; I244-T248 WeakPolarHBondContact O-CB 3.48Å; I244-T248 PolarHBondContact O-N 3.43Å; I244-T248 PolarHBondContact O-OG1 3.11Å
245	M	93.6	Very high	95.2	Very high	41 Å²	41	30.3 Å²	30.3	20%	0.202	17%	0.166	C	C	.	.	H	α-helix	trans	-63.3	-51	-177.8	-72.3	-61.3	-65.7	0	0	111.9	V241 C243 F249	V241-M245 HydrophobicContact CG1-CG 4.19Å; V241-M245 WeakPolarHBondContact O-CB 3.46Å; V241-M245 VanDerWaalsContact O-CG 3.31Å; V241-M245 WeakPolarHBondContact O-CG 3.45Å; V241-M245 PolarHBondContact O-N 3.18Å; C243-M245 PolarHBondContact O-N 2.88Å; M245-F249 WeakPolarHBondContact O-CB 3.19Å; M245-F249 PolarHBondContact O-N 2.7Å
246	K	94.6	Very high	95	Very high	0 Å²	0	31.6 Å²	31.6	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-64.7	-42	-179.3	-72.7	175	168.7	-172	0	112.3	I16 V21 L24 S211 Y212 A242 S250	I16-K246 WeakPolarHBondContact O-CE 3.48Å; I16-K246 PolarHBondContact O-NZ 2.86Å; V21-K246 HydrophobicContact CG2-CG 4.29Å; L24-K246 HydrophobicContact CD1-CB 3.79Å; L24-K246 HydrophobicContact CD1-CD 3.64Å; L24-K246 HydrophobicContact CD1-CG 3.62Å; S211-K246 PolarHBondContact O-NZ 3.31Å; S211-K246 PolarHBondContact OG-NZ 3Å; Y212-K246 HydrophobicContact CE1-CD 3.92Å; Y212-K246 HydrophobicContact CE2-CD 4.1Å; Y212-K246 WeakPolarHBondContact OH-CD 3.41Å; A242-K246 WeakPolarHBondContact O-CB 3.23Å; A242-K246 VanDerWaalsContact O-CG 3.23Å; A242-K246 WeakPolarHBondContact O-CG 3.1Å; A242-K246 PolarHBondContact O-N 3.4Å; K246-S250 WeakPolarHBondContact O-CB 3.44Å; K246-S250 PolarHBondContact O-N 3.43Å; K246-S250 PolarHBondContact O-OG 3.44Å
247	T	95.7	Very high	94.7	Very high	26 Å²	26	32 Å²	32	16%	0.16	17%	0.17	C	C	.	.	H	α-helix	trans	-65	-48.8	179.6	-55.7	0	0	0	0	110.4	L36 V40 C243 S250 L251	L36-T247 HydrophobicContact CD1-CG2 3.79Å; V40-T247 HydrophobicContact CG2-CG2 4.23Å; C243-T247 WeakPolarHBondContact O-CB 3.29Å; C243-T247 PolarHBondContact O-N 3.47Å; C243-T247 PolarHBondContact O-OG1 3.11Å; T247-S250 PolarHBondContact O-N 2.9Å; T247-L251 WeakPolarHBondContact O-CB 3.05Å; T247-L251 PolarHBondContact O-N 3.09Å
248	T	94.7	Very high	94.4	Very high	54 Å²	54	23.5 Å²	23.5	33%	0.331	14%	0.137	S	C	.	.	H	α-helix	trans	-62.4	-50.7	178.6	-53.1	0	0	0	0	110.6	I177 I244 S250 L252	I177-T248 HydrophobicContact CD1-CG2 4.02Å; I177-T248 HydrophobicContact CG1-CG2 4.45Å; I244-T248 VanDerWaalsContact O-CB 3.28Å; I244-T248 WeakPolarHBondContact O-CB 3.48Å; I244-T248 PolarHBondContact O-N 3.43Å; I244-T248 PolarHBondContact O-OG1 3.11Å; T248-S250 PolarHBondContact O-N 3.13Å; T248-L252 HydrophobicContact CG2-CD1 3.85Å; T248-L252 HydrophobicContact CG2-CG 4.22Å; T248-L252 WeakPolarHBondContact O-CB 3.09Å; T248-L252 WeakPolarHBondContact O-CG 3.25Å; T248-L252 PolarHBondContact O-N 3.22Å
249	F	93.7	Very high	94	Very high	4 Å²	4	27.8 Å²	27.8	2%	0.018	17%	0.165	C	C	.	.	H	α-helix	trans	-56.5	-48.8	179.5	-179	-90.3	0	0	0	112	V21 L22 P25 V176 M245 A253 I265	V21-F249 HydrophobicContact CG2-CD1 3.77Å; V21-F249 HydrophobicContact CG2-CE1 4.09Å; V21-F249 HydrophobicContact CG2-CG 4.17Å; L22-F249 HydrophobicContact CD2-CZ 4.47Å; P25-F249 HydrophobicContact CG-CD1 4.09Å; P25-F249 HydrophobicContact CG-CE1 3.79Å; V176-F249 HydrophobicContact CB-CD2 4.36Å; V176-F249 HydrophobicContact CB-CE2 3.73Å; V176-F249 HydrophobicContact CG1-CD2 4.16Å; V176-F249 HydrophobicContact CG1-CE2 3.53Å; V176-F249 HydrophobicContact CG1-CZ 4.11Å; V176-F249 HydrophobicContact CG2-CE2 4.09Å; M245-F249 WeakPolarHBondContact O-CB 3.19Å; M245-F249 PolarHBondContact O-N 2.7Å; F249-A253 VanDerWaalsContact O-CB 3.23Å; F249-A253 WeakPolarHBondContact O-CB 3.34Å; F249-A253 PolarHBondContact O-N 3.44Å; F249-I265 HydrophobicContact CE1-CG2 4.07Å; F249-I265 HydrophobicContact CZ-CG2 3.81Å
250	S	94.8	Very high	93.7	Very high	0 Å²	0	35 Å²	35	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-72.6	-42.2	-174.9	-48.4	0	0	0	0	112	L24 K246 T247 T248 A253 V254	L24-S250 WeakPolarHBondContact CB-OG 3.39Å; K246-S250 WeakPolarHBondContact O-CB 3.44Å; K246-S250 PolarHBondContact O-N 3.43Å; K246-S250 PolarHBondContact O-OG 3.44Å; T247-S250 PolarHBondContact O-N 2.9Å; T248-S250 PolarHBondContact O-N 3.13Å; S250-A253 PolarHBondContact O-N 3.32Å; S250-V254 VanDerWaalsContact O-CG2 3.29Å; S250-V254 WeakPolarHBondContact O-CG2 3.4Å; S250-V254 PolarHBondContact O-N 2.69Å
251	L	94.6	Very high	93.4	Very high	34 Å²	34	33.8 Å²	33.8	18%	0.178	19%	0.185	C	C	.	.	H	α-helix	trans	-62.6	-47.9	177.5	179.3	60.8	0	0	0	111.4	L36 W189 L192 T247 A253 V254 L255	L36-L251 HydrophobicContact CD2-CD1 4.42Å; W189-L251 HydrophobicContact CH2-CD2 4.46Å; W189-L251 HydrophobicContact CZ3-CD1 4.1Å; L192-L251 HydrophobicContact CD1-CD1 3.82Å; T247-L251 WeakPolarHBondContact O-CB 3.05Å; T247-L251 PolarHBondContact O-N 3.09Å; L251-A253 VanDerWaalsContact C-N 3.33Å; L251-A253 PolarHBondContact O-N 2.87Å; L251-V254 PolarHBondContact O-N 3.47Å; L251-L255 HydrophobicContact CD1-CD1 4.27Å; L251-L255 HydrophobicContact CD1-CG 4.29Å; L251-L255 HydrophobicContact CG-CD1 4.14Å; L251-L255 WeakPolarHBondContact O-CG 3.36Å; L251-L255 PolarHBondContact O-N 3.42Å
252	L	94.4	Very high	93.2	Very high	20 Å²	20	32.1 Å²	32.1	11%	0.105	18%	0.176	C	C	.	.	H	α-helix	trans	-66.2	-36.8	-179	-65.3	-169.9	0	0	0	112.4	I177 C180 L181 W187 T248 L255 T256	I177-L252 HydrophobicContact CB-CD1 4.34Å; I177-L252 HydrophobicContact CG1-CD1 4.25Å; I177-L252 HydrophobicContact CG2-CD1 3.74Å; C180-L252 HydrophobicContact CB-CB 3.87Å; L181-L252 HydrophobicContact CD2-CD1 4.45Å; L181-L252 HydrophobicContact CG-CD1 4.33Å; W187-L252 HydrophobicContact CH2-CD2 3.32Å; W187-L252 HydrophobicContact CZ2-CD2 3.74Å; W187-L252 HydrophobicContact CZ3-CD2 4Å; T248-L252 HydrophobicContact CG2-CD1 3.85Å; T248-L252 HydrophobicContact CG2-CG 4.22Å; T248-L252 WeakPolarHBondContact O-CB 3.09Å; T248-L252 WeakPolarHBondContact O-CG 3.25Å; T248-L252 PolarHBondContact O-N 3.22Å; L252-L255 HydrophobicContact CD2-CD1 4.45Å; L252-L255 PolarHBondContact O-N 2.88Å; L252-T256 WeakPolarHBondContact O-CB 3.45Å; L252-T256 PolarHBondContact O-N 3.16Å; L252-T256 VanDerWaalsContact O-N 3.11Å; L252-T256 PolarHBondContact O-OG1 3.4Å
253	A	92.8	Very high	92.8	Very high	0 Å²	0	33.8 Å²	33.8	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-62.1	-47.8	173.1	0	0	0	0	0	111.5	P25 F249 S250 L251 L255 T256 W257 I265	P25-A253 HydrophobicContact CB-CB 3.7Å; P25-A253 HydrophobicContact CG-CB 3.71Å; F249-A253 VanDerWaalsContact O-CB 3.23Å; F249-A253 WeakPolarHBondContact O-CB 3.34Å; F249-A253 PolarHBondContact O-N 3.44Å; S250-A253 PolarHBondContact O-N 3.32Å; L251-A253 VanDerWaalsContact C-N 3.33Å; L251-A253 PolarHBondContact O-N 2.87Å; A253-L255 VanDerWaalsContact C-N 3.35Å; A253-L255 PolarHBondContact O-N 3.29Å; A253-T256 PolarHBondContact O-N 2.87Å; A253-T256 VanDerWaalsContact O-N 3.1Å; A253-W257 HydrophobicContact CB-CE3 4.05Å; A253-W257 HydrophobicContact CB-CZ3 3.94Å; A253-W257 VanDerWaalsContact O-CE3 3.32Å; A253-W257 PolarHBondContact O-N 3.31Å; A253-I265 HydrophobicContact CB-CD1 3.93Å; A253-I265 HydrophobicContact CB-CG1 4.2Å
254	V	93.4	Very high	92.4	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-62.4	-40.6	177.6	172.6	0	0	0	0	111.9	P25 L28 V29 L192 S250 L251 T256 G258	P25-V254 HydrophobicContact CB-CG2 4.42Å; P25-V254 WeakPolarHBondContact O-CG2 3.27Å; L28-V254 HydrophobicContact CB-CG2 3.8Å; V29-V254 HydrophobicContact CG2-CG1 4.19Å; V29-V254 HydrophobicContact CG2-CG2 3.82Å; L192-V254 HydrophobicContact CD2-CG1 3.89Å; L192-V254 HydrophobicContact CG-CG1 4.01Å; S250-V254 VanDerWaalsContact O-CG2 3.29Å; S250-V254 WeakPolarHBondContact O-CG2 3.4Å; S250-V254 PolarHBondContact O-N 2.69Å; L251-V254 PolarHBondContact O-N 3.47Å; V254-T256 PolarHBondContact O-N 3.34Å; V254-G258 WeakPolarHBondContact O-CA 3.17Å; V254-G258 PolarHBondContact O-N 2.9Å
255	L	93.3	Very high	92	Very high	2 Å²	2	28 Å²	28	1%	0.01	15%	0.153	C	C	.	.	H	α-helix	trans	-65.3	-26.5	176.8	-69.5	174.7	0	0	0	112.8	W187 W189 L251 L252 A253	W187-L255 WeakPolarHBondContact CA-O 3.15Å; W187-L255 HydrophobicContact CB-CB 4.14Å; W187-L255 VanDerWaalsContact CD1-O 3.26Å; W187-L255 HydrophobicContact CD2-CB 3.88Å; W187-L255 HydrophobicContact CD2-CD1 4.14Å; W187-L255 HydrophobicContact CE3-CB 4.45Å; W187-L255 HydrophobicContact CE3-CD1 3.86Å; W187-L255 HydrophobicContact CG-CB 3.73Å; W187-L255 HydrophobicContact CZ3-CD1 4.22Å; W189-L255 HydrophobicContact CD2-CD2 3.8Å; W189-L255 HydrophobicContact CE3-CD2 3.83Å; W189-L255 HydrophobicContact CG-CD2 4.27Å; W189-L255 HydrophobicContact CH2-CD1 3.84Å; W189-L255 HydrophobicContact CH2-CD2 4.42Å; W189-L255 HydrophobicContact CZ2-CD1 3.88Å; W189-L255 HydrophobicContact CZ2-CD2 4.39Å; W189-L255 HydrophobicContact CZ3-CD1 4.26Å; W189-L255 HydrophobicContact CZ3-CD2 4.15Å; L251-L255 HydrophobicContact CD1-CD1 4.27Å; L251-L255 HydrophobicContact CD1-CG 4.29Å; L251-L255 HydrophobicContact CG-CD1 4.14Å; L251-L255 WeakPolarHBondContact O-CG 3.36Å; L251-L255 PolarHBondContact O-N 3.42Å; L252-L255 HydrophobicContact CD2-CD1 4.45Å; L252-L255 PolarHBondContact O-N 2.88Å; A253-L255 VanDerWaalsContact C-N 3.35Å; A253-L255 PolarHBondContact O-N 3.29Å
256	T	92.8	Very high	91.6	Very high	28 Å²	28	26.1 Å²	26.1	17%	0.172	14%	0.144	C	C	.	.	H	α-helix	trans	-85.8	-45.5	-178.2	-56.4	0	0	0	0	112.5	C180 C183 W187 L252 A253 V254	C180-T256 WeakPolarHBondContact CB-OG1 3.31Å; C183-T256 HydrophobicContact CB-CG2 3.89Å; W187-T256 PolarHBondContact NE1-OG1 2.72Å; W187-T256 VanDerWaalsContact NE1-OG1 3.11Å; L252-T256 WeakPolarHBondContact O-CB 3.45Å; L252-T256 PolarHBondContact O-N 3.16Å; L252-T256 VanDerWaalsContact O-N 3.11Å; L252-T256 PolarHBondContact O-OG1 3.4Å; A253-T256 PolarHBondContact O-N 2.87Å; A253-T256 VanDerWaalsContact O-N 3.1Å; V254-T256 PolarHBondContact O-N 3.34Å
257	W	91.4	Very high	91.2	Very high	30 Å²	30	28.6 Å²	28.6	11%	0.114	16%	0.157	C	C	.	.	H	α-helix	trans	-109.9	-19.7	-174.1	-66.7	-72.5	0	0	0	114.7	Y179 A253 E260 I265 N268 L269	Y179-W257 HydrophobicContact CD1-CH2 4.09Å; Y179-W257 HydrophobicContact CD1-CZ2 4.06Å; Y179-W257 HydrophobicContact CE1-CH2 4.1Å; Y179-W257 AromaticContact CE1-CZ2 3.59Å; Y179-W257 HydrophobicContact CE1-CZ2 3.59Å; A253-W257 HydrophobicContact CB-CE3 4.05Å; A253-W257 HydrophobicContact CB-CZ3 3.94Å; A253-W257 VanDerWaalsContact O-CE3 3.32Å; A253-W257 PolarHBondContact O-N 3.31Å; W257-E260 WeakPolarHBondContact O-CB 3.34Å; W257-E260 PolarHBondContact O-N 2.87Å; W257-E260 VanDerWaalsContact O-N 3.09Å; W257-I265 HydrophobicContact CD2-CD1 4.38Å; W257-I265 HydrophobicContact CE3-CD1 3.58Å; W257-I265 HydrophobicContact CE3-CG1 4.33Å; W257-I265 HydrophobicContact CZ3-CD1 3.73Å; W257-I265 HydrophobicContact CZ3-CG1 3.96Å; W257-N268 HydrophobicContact CD2-CB 3.79Å; W257-N268 HydrophobicContact CG-CB 3.87Å; W257-N268 HydrophobicContact CZ2-CB 4.1Å; W257-N268 PolarHBondContact NE1-O 2.9Å; W257-N268 VanDerWaalsContact NE1-O 3.15Å; W257-L269 HydrophobicContact CH2-CD2 4.17Å; W257-L269 HydrophobicContact CZ2-CD2 4.13Å
258	G	90	Very high	90.8	Very high	0 Å²	0	28.6 Å²	28.6	0%	0	16%	0.156	C	C	.	.	G	3₁₀ helix	trans	52.5	-132.9	175.8	0	0	0	0	0	113	V29 V254 E260 T261	V29-G258 WeakPolarHBondContact CG2-O 3.32Å; V254-G258 WeakPolarHBondContact O-CA 3.17Å; V254-G258 PolarHBondContact O-N 2.9Å; G258-E260 PolarHBondContact O-N 3.22Å; G258-E260 VanDerWaalsContact O-N 3.11Å; G258-T261 WeakPolarHBondContact O-CB 3.25Å; G258-T261 PolarHBondContact O-N 3.1Å; G258-T261 VanDerWaalsContact O-N 3.11Å; G258-T261 PolarHBondContact O-OG1 2.92Å
259	P	87.9	Confident	90.4	Very high	96 Å²	96	26.3 Å²	26.3	62%	0.623	14%	0.142	S	C	*	.	G	3₁₀ helix	trans	-59.5	-18.8	179.6	-24.2	34.3	0	0	0	115.4	F191 T261	F191-P259 HydrophobicContact CD1-CG 4.23Å; P259-T261 PolarHBondContact O-N 3.39Å
260	E	89.8	Confident	90	Very high	157 Å²	157	27.7 Å²	27.7	73%	0.734	15%	0.151	S	C	*	.	G	3₁₀ helix	trans	-81.4	-1.8	178.9	-59.5	-173.3	175.2	0	0	112.8	W257 G258 S262 N268	W257-E260 WeakPolarHBondContact O-CB 3.34Å; W257-E260 PolarHBondContact O-N 2.87Å; W257-E260 VanDerWaalsContact O-N 3.09Å; G258-E260 PolarHBondContact O-N 3.22Å; G258-E260 VanDerWaalsContact O-N 3.11Å; E260-S262 PolarHBondContact O-N 2.95Å; E260-N268 PolarHBondContact O-ND2 3.43Å
261	T	90.7	Very high	89.5	Confident	7 Å²	7	32.9 Å²	32.9	4%	0.043	19%	0.185	C	C	.	.			trans	-58.4	122.2	179.1	-58.4	0	0	0	0	111.3	P25 F26 V29 G258 P259 I265	P25-T261 HydrophobicContact CB-CG2 3.82Å; F26-T261 HydrophobicContact CB-CG2 4.24Å; F26-T261 WeakPolarHBondContact CD2-O 3.46Å; V29-T261 HydrophobicContact CG2-CG2 4.34Å; G258-T261 WeakPolarHBondContact O-CB 3.25Å; G258-T261 PolarHBondContact O-N 3.1Å; G258-T261 VanDerWaalsContact O-N 3.11Å; G258-T261 PolarHBondContact O-OG1 2.92Å; P259-T261 PolarHBondContact O-N 3.39Å; T261-I265 HydrophobicContact CG2-CD1 3.87Å
262	S	90.4	Very high	89	Confident	39 Å²	39	36.9 Å²	36.9	27%	0.273	21%	0.206	S	C	.	.			trans	-81.8	159.1	176.5	-64.9	0	0	0	0	111.9	E260 V264 N268	E260-S262 PolarHBondContact O-N 2.95Å; S262-V264 PolarHBondContact O-N 3.14Å; S262-V264 VanDerWaalsContact O-N 3.14Å; S262-N268 WeakPolarHBondContact CB-OD1 3.44Å; S262-N268 PolarHBondContact N-OD1 3.37Å
263	E	86.7	Confident	88.5	Confident	37 Å²	37	39.3 Å²	39.3	17%	0.173	22%	0.219	C	C	.	.	S	Bend	trans	-56.3	-30.8	176.3	-63.6	-165	172.8	0	0	112.8	G23 F26 R346 F347 S348	G23-E263 WeakPolarHBondContact CA-O 3.46Å; F26-E263 HydrophobicContact CD1-CG 4.18Å; F26-E263 HydrophobicContact CD2-CG 4.29Å; F26-E263 HydrophobicContact CE1-CG 3.93Å; F26-E263 HydrophobicContact CE2-CG 4.06Å; F26-E263 HydrophobicContact CG-CG 4.34Å; F26-E263 HydrophobicContact CZ-CG 3.87Å; E263-R346 IonicContact OE1-NH1 3.81Å; E263-R346 PolarHBondContact OE1-NH1 2.98Å; E263-F347 PolarHBondContact OE2-N 3.27Å; E263-F347 VanDerWaalsContact OE2-N 3.1Å; E263-S348 VanDerWaalsContact CD-CB 3.46Å; E263-S348 PolarHBondContact OE1-OG 2.99Å; E263-S348 WeakPolarHBondContact OE2-CB 3.42Å; E263-S348 PolarHBondContact OE2-N 3.15Å; E263-S348 PolarHBondContact OE2-OG 3.2Å
264	V	88.6	Confident	88.2	Confident	9 Å²	9	43 Å²	43	6%	0.055	23%	0.233	C	C	.	.	S	Bend	trans	-114.5	108.9	169.5	-170.6	0	0	0	0	107.6	L22 S262 T266 D267 F347	L22-V264 HydrophobicContact CB-CG1 4.25Å; L22-V264 HydrophobicContact CD1-CG1 3.93Å; S262-V264 PolarHBondContact O-N 3.14Å; S262-V264 VanDerWaalsContact O-N 3.14Å; V264-T266 VanDerWaalsContact CG1-OG1 3.32Å; V264-T266 WeakPolarHBondContact CG1-OG1 3.22Å; V264-T266 PolarHBondContact O-N 3.44Å; V264-D267 WeakPolarHBondContact O-CB 3.34Å; V264-D267 PolarHBondContact O-N 3.1Å; V264-F347 HydrophobicContact CG2-CD1 4.08Å; V264-F347 HydrophobicContact CG2-CG 4.46Å
265	I	87.4	Confident	87.9	Confident	4 Å²	4	45.1 Å²	45.1	2%	0.021	25%	0.247	C	C	.	.	G	3₁₀ helix	trans	-56.2	-22	-171.9	-169.3	59.7	0	0	0	115.1	L22 P25 F249 A253 W257 T261 D267 N268	L22-I265 HydrophobicContact CB-CG2 4.17Å; L22-I265 HydrophobicContact CD2-CG2 3.62Å; L22-I265 HydrophobicContact CG-CG2 4.49Å; L22-I265 PolarHBondContact O-N 3.28Å; P25-I265 HydrophobicContact CB-CD1 3.99Å; P25-I265 HydrophobicContact CB-CG1 4.47Å; P25-I265 HydrophobicContact CG-CB 4.19Å; P25-I265 HydrophobicContact CG-CD1 4.14Å; P25-I265 HydrophobicContact CG-CG1 4.07Å; F249-I265 HydrophobicContact CE1-CG2 4.07Å; F249-I265 HydrophobicContact CZ-CG2 3.81Å; A253-I265 HydrophobicContact CB-CD1 3.93Å; A253-I265 HydrophobicContact CB-CG1 4.2Å; W257-I265 HydrophobicContact CD2-CD1 4.38Å; W257-I265 HydrophobicContact CE3-CD1 3.58Å; W257-I265 HydrophobicContact CE3-CG1 4.33Å; W257-I265 HydrophobicContact CZ3-CD1 3.73Å; W257-I265 HydrophobicContact CZ3-CG1 3.96Å; T261-I265 HydrophobicContact CG2-CD1 3.87Å; I265-D267 PolarHBondContact O-N 3.19Å; I265-N268 WeakPolarHBondContact O-CB 3.36Å; I265-N268 PolarHBondContact O-N 3.21Å
266	T	85.1	Confident	87.5	Confident	2 Å²	2	49.7 Å²	49.7	1%	0.012	27%	0.274	C	S	.	.	G	3₁₀ helix	trans	-65.5	-23.8	177	45.9	0	0	0	0	114.4	V264 N268 L269 V277 N278 L281	V264-T266 VanDerWaalsContact CG1-OG1 3.32Å; V264-T266 WeakPolarHBondContact CG1-OG1 3.22Å; V264-T266 PolarHBondContact O-N 3.44Å; T266-N268 PolarHBondContact O-N 2.87Å; T266-L269 HydrophobicContact CG2-CD1 4.07Å; T266-L269 VanDerWaalsContact O-CB 3.3Å; T266-L269 WeakPolarHBondContact O-CB 3.11Å; T266-L269 PolarHBondContact O-N 3.1Å; T266-V277 HydrophobicContact CG2-CG1 4.02Å; T266-N278 WeakPolarHBondContact CB-OD1 3.47Å; T266-N278 WeakPolarHBondContact CG2-OD1 3.35Å; T266-N278 PolarHBondContact OG1-OD1 3.49Å; T266-L281 HydrophobicContact CG2-CD1 3.09Å
267	D	86.2	Confident	87.3	Confident	52 Å²	52	49.4 Å²	49.4	28%	0.278	27%	0.273	S	S	.	.	G	3₁₀ helix	trans	-69.5	-14.2	179.9	-59.9	-12.8	0	0	0	111.4	V264 I265 R274	V264-D267 WeakPolarHBondContact O-CB 3.34Å; V264-D267 PolarHBondContact O-N 3.1Å; I265-D267 PolarHBondContact O-N 3.19Å; D267-R274 PolarHBondContact O-NH1 3.43Å; D267-R274 PolarHBondContact O-NH2 3.38Å
268	N	88.4	Confident	87.2	Confident	25 Å²	25	48 Å²	48	13%	0.134	27%	0.267	C	S	.	.	G	3₁₀ helix	trans	-87.5	-9.4	173.1	-61.1	102.8	0	0	0	113.6	W257 E260 S262 I265 T266	W257-N268 HydrophobicContact CD2-CB 3.79Å; W257-N268 HydrophobicContact CG-CB 3.87Å; W257-N268 HydrophobicContact CZ2-CB 4.1Å; W257-N268 PolarHBondContact NE1-O 2.9Å; W257-N268 VanDerWaalsContact NE1-O 3.15Å; E260-N268 PolarHBondContact O-ND2 3.43Å; S262-N268 WeakPolarHBondContact CB-OD1 3.44Å; S262-N268 PolarHBondContact N-OD1 3.37Å; I265-N268 WeakPolarHBondContact O-CB 3.36Å; I265-N268 PolarHBondContact O-N 3.21Å; T266-N268 PolarHBondContact O-N 2.87Å
269	L	85.8	Confident	87.2	Confident	7 Å²	7	52.9 Å²	52.9	4%	0.037	29%	0.293	C	S	.	.	S	Bend	trans	-73.1	148.8	180	-68.9	171.6	0	0	0	111.8	Y179 W257 T266 R274 V277	Y179-L269 HydrophobicContact CD1-CD2 4.45Å; W257-L269 HydrophobicContact CH2-CD2 4.17Å; W257-L269 HydrophobicContact CZ2-CD2 4.13Å; T266-L269 HydrophobicContact CG2-CD1 4.07Å; T266-L269 VanDerWaalsContact O-CB 3.3Å; T266-L269 WeakPolarHBondContact O-CB 3.11Å; T266-L269 PolarHBondContact O-N 3.1Å; L269-R274 HydrophobicContact CB-CB 4.18Å; L269-R274 PolarHBondContact O-NE 3.38Å; L269-R274 PolarHBondContact O-NH2 3.37Å; L269-V277 HydrophobicContact CD1-CB 3.71Å; L269-V277 HydrophobicContact CD1-CG1 3.58Å; L269-V277 HydrophobicContact CD1-CG2 3.96Å
270	P	85.8	Confident	87.3	Confident	32 Å²	32	51 Å²	51	21%	0.208	28%	0.281	C	S	.	.			trans	-65.3	151.2	178.4	30.3	-36.8	0	0	0	111.1	Y179 N272 L273 R274	Y179-P270 HydrophobicContact CE2-CG 4.3Å; P270-N272 VanDerWaalsContact CB-OD1 3.31Å; P270-N272 WeakPolarHBondContact CB-OD1 3.4Å; P270-N272 WeakPolarHBondContact CG-OD1 3.39Å; P270-N272 PolarHBondContact O-N 2.99Å; P270-N272 VanDerWaalsContact O-N 3.08Å; P270-L273 HydrophobicContact CG-CB 4.12Å; P270-L273 HydrophobicContact CG-CD1 3.82Å; P270-L273 HydrophobicContact CG-CG 4.04Å; P270-L273 PolarHBondContact O-N 3.44Å; P270-R274 WeakPolarHBondContact O-CB 3.34Å; P270-R274 PolarHBondContact O-N 3.21Å
271	P	84.6	Confident	87.4	Confident	109 Å²	109	43.6 Å²	43.6	71%	0.708	25%	0.247	S	C	*	.	T	Hydrogen-bonded Turn	trans	-63.1	-22.5	-168	24.6	-35.2	0	0	0	114.1	P275	P271-P275 WeakPolarHBondContact O-CD 3.39Å
272	N	84.5	Confident	87.5	Confident	118 Å²	118	43.6 Å²	43.6	63%	0.631	25%	0.246	S	C	*	.	T	Hydrogen-bonded Turn	trans	-77.1	-29.9	175.9	62.4	-39.6	0	0	0	113.5	P270	P270-N272 VanDerWaalsContact CB-OD1 3.31Å; P270-N272 WeakPolarHBondContact CB-OD1 3.4Å; P270-N272 WeakPolarHBondContact CG-OD1 3.39Å; P270-N272 PolarHBondContact O-N 2.99Å; P270-N272 VanDerWaalsContact O-N 3.08Å
273	L	82.5	Confident	87.6	Confident	71 Å²	71	44 Å²	44	37%	0.372	25%	0.252	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.7	-30.3	-179.9	-63.3	-179.6	0	0	0	112.2	Y179 P270 V276 V277	Y179-L273 HydrophobicContact CD2-CD1 4.23Å; Y179-L273 HydrophobicContact CE2-CD1 4.38Å; P270-L273 HydrophobicContact CG-CB 4.12Å; P270-L273 HydrophobicContact CG-CD1 3.82Å; P270-L273 HydrophobicContact CG-CG 4.04Å; P270-L273 PolarHBondContact O-N 3.44Å; L273-V276 PolarHBondContact O-N 2.99Å; L273-V277 WeakPolarHBondContact O-CG2 3.41Å; L273-V277 PolarHBondContact O-N 2.99Å; L273-V277 VanDerWaalsContact O-N 3.1Å
274	R	86.7	Confident	87.9	Confident	77 Å²	77	42.2 Å²	42.2	29%	0.291	24%	0.244	S	C	.	.	H	α-helix	trans	-53.5	-49.3	-173.1	-175.2	-172.7	-54.7	-158.3	-2	113.8	D267 L269 P270 V276 V277 N278	D267-R274 PolarHBondContact O-NH1 3.43Å; D267-R274 PolarHBondContact O-NH2 3.38Å; L269-R274 HydrophobicContact CB-CB 4.18Å; L269-R274 PolarHBondContact O-NE 3.38Å; L269-R274 PolarHBondContact O-NH2 3.37Å; P270-R274 WeakPolarHBondContact O-CB 3.34Å; P270-R274 PolarHBondContact O-N 3.21Å; R274-V276 VanDerWaalsContact C-N 3.32Å; R274-V276 PolarHBondContact O-N 3.24Å; R274-V277 PolarHBondContact O-N 2.94Å; R274-N278 VanDerWaalsContact O-CB 3.26Å; R274-N278 WeakPolarHBondContact O-CB 3.33Å; R274-N278 PolarHBondContact O-N 2.99Å; R274-N278 PolarHBondContact O-OD1 3.11Å
275	P	87.3	Confident	88.1	Confident	45 Å²	45	41.8 Å²	41.8	29%	0.292	24%	0.241	S	C	.	.	H	α-helix	trans	-62.6	-38.4	-177.1	-23.3	34.6	0	0	0	113.1	P271 L279	P271-P275 WeakPolarHBondContact O-CD 3.39Å; P275-L279 WeakPolarHBondContact O-CB 3.17Å; P275-L279 PolarHBondContact O-N 3.11Å
276	V	86.1	Confident	88.4	Confident	98 Å²	98	43 Å²	43	59%	0.594	25%	0.248	S	C	*	.	H	α-helix	trans	-68.7	-47.4	180	179.5	0	0	0	0	110.4	L273 R274 L279 C280	L273-V276 PolarHBondContact O-N 2.99Å; R274-V276 VanDerWaalsContact C-N 3.32Å; R274-V276 PolarHBondContact O-N 3.24Å; V276-L279 PolarHBondContact O-N 3.22Å; V276-C280 PolarHBondContact O-N 2.95Å; V276-C280 PolarHBondContact O-SG 3.33Å; V276-C280 VanDerWaalsContact O-SG 3.36Å
277	V	87.2	Confident	88.7	Confident	22 Å²	22	44.6 Å²	44.6	13%	0.133	26%	0.256	C	S	.	.	H	α-helix	trans	-65.6	-40.1	179	178.4	0	0	0	0	111.1	I172 T266 L269 L273 R274 L279 C280 L281	I172-V277 HydrophobicContact CG2-CG1 4.39Å; T266-V277 HydrophobicContact CG2-CG1 4.02Å; L269-V277 HydrophobicContact CD1-CB 3.71Å; L269-V277 HydrophobicContact CD1-CG1 3.58Å; L269-V277 HydrophobicContact CD1-CG2 3.96Å; L273-V277 WeakPolarHBondContact O-CG2 3.41Å; L273-V277 PolarHBondContact O-N 2.99Å; L273-V277 VanDerWaalsContact O-N 3.1Å; R274-V277 PolarHBondContact O-N 2.94Å; V277-L279 PolarHBondContact O-N 2.62Å; V277-C280 PolarHBondContact O-N 3.03Å; V277-L281 HydrophobicContact CG1-CD1 3.83Å; V277-L281 HydrophobicContact CG1-CG 4.43Å; V277-L281 WeakPolarHBondContact O-CB 3.41Å; V277-L281 WeakPolarHBondContact O-CG 3.32Å; V277-L281 PolarHBondContact O-N 3.35Å
278	N	90.3	Very high	89.1	Confident	0 Å²	0	42.1 Å²	42.1	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-63.7	-40.5	177	-74.6	12	0	0	0	111.8	L123 D126 S127 T266 R274 L281 L282	L123-N278 HydrophobicContact CB-CB 4.46Å; L123-N278 HydrophobicContact CD2-CB 4.08Å; D126-N278 VanDerWaalsContact CB-ND2 3.28Å; D126-N278 WeakPolarHBondContact CB-ND2 3.3Å; S127-N278 WeakPolarHBondContact OG-CB 2.85Å; T266-N278 WeakPolarHBondContact CB-OD1 3.47Å; T266-N278 WeakPolarHBondContact CG2-OD1 3.35Å; T266-N278 PolarHBondContact OG1-OD1 3.49Å; R274-N278 VanDerWaalsContact O-CB 3.26Å; R274-N278 WeakPolarHBondContact O-CB 3.33Å; R274-N278 PolarHBondContact O-N 2.99Å; R274-N278 PolarHBondContact O-OD1 3.11Å; N278-L281 PolarHBondContact O-N 3.22Å; N278-L282 VanDerWaalsContact O-CB 3.29Å; N278-L282 WeakPolarHBondContact O-CB 3.2Å; N278-L282 PolarHBondContact O-N 2.55Å
279	L	90.4	Very high	89.4	Confident	103 Å²	103	41 Å²	41	54%	0.539	24%	0.237	S	C	.	.	H	α-helix	trans	-64.9	-41.3	175.3	-174.6	62.4	0	0	0	112	S127 P275 V276 V277 L282 A283	S127-L279 PolarHBondContact OG-N 2.76Å; P275-L279 WeakPolarHBondContact O-CB 3.17Å; P275-L279 PolarHBondContact O-N 3.11Å; V276-L279 PolarHBondContact O-N 3.22Å; V277-L279 PolarHBondContact O-N 2.62Å; L279-L282 HydrophobicContact CD1-CD2 4.29Å; L279-L282 PolarHBondContact O-N 3.06Å; L279-A283 PolarHBondContact O-N 3.5Å
280	C	89.9	Confident	89.8	Confident	56 Å²	56	40.9 Å²	40.9	38%	0.378	24%	0.236	S	C	.	.	H	α-helix	trans	-63.7	-40.7	174.8	-69	0	0	0	0	112.1	I172 V276 V277 A283 K284	I172-C280 HydrophobicContact CD1-CB 3.79Å; I172-C280 HydrophobicContact CG1-CB 4Å; V276-C280 PolarHBondContact O-N 2.95Å; V276-C280 PolarHBondContact O-SG 3.33Å; V276-C280 VanDerWaalsContact O-SG 3.36Å; V277-C280 PolarHBondContact O-N 3.03Å; C280-A283 PolarHBondContact O-N 3.28Å; C280-K284 WeakPolarHBondContact O-CB 3.36Å; C280-K284 PolarHBondContact O-N 3.02Å
281	L	91.1	Very high	90.2	Very high	2 Å²	2	39.6 Å²	39.6	1%	0.01	23%	0.227	C	C	.	.	H	α-helix	trans	-72.1	-32.6	176.9	-76.2	167.3	0	0	0	112.9	I19 L22 L123 I172 T266 V277 N278 K284 A285	I19-L281 HydrophobicContact CD1-CB 4.29Å; I19-L281 HydrophobicContact CD1-CD2 4.04Å; L22-L281 HydrophobicContact CD1-CD1 3.99Å; L22-L281 HydrophobicContact CD1-CD2 4.2Å; L22-L281 HydrophobicContact CD2-CD1 3.77Å; L22-L281 HydrophobicContact CD2-CD2 3.91Å; L22-L281 HydrophobicContact CG-CD2 4.44Å; L123-L281 HydrophobicContact CD1-CB 3.69Å; L123-L281 HydrophobicContact CD2-CB 4.45Å; I172-L281 HydrophobicContact CD1-CD2 3.78Å; I172-L281 HydrophobicContact CD1-CG 4.01Å; I172-L281 HydrophobicContact CG2-CD1 4.42Å; I172-L281 HydrophobicContact CG2-CD2 3.83Å; I172-L281 HydrophobicContact CG2-CG 4.06Å; T266-L281 HydrophobicContact CG2-CD1 3.09Å; V277-L281 HydrophobicContact CG1-CD1 3.83Å; V277-L281 HydrophobicContact CG1-CG 4.43Å; V277-L281 WeakPolarHBondContact O-CB 3.41Å; V277-L281 WeakPolarHBondContact O-CG 3.32Å; V277-L281 PolarHBondContact O-N 3.35Å; N278-L281 PolarHBondContact O-N 3.22Å; L281-K284 HydrophobicContact CD2-CD 3.96Å; L281-K284 WeakPolarHBondContact O-CB 3.49Å; L281-K284 PolarHBondContact O-N 2.82Å; L281-A285 WeakPolarHBondContact O-CB 3.3Å; L281-A285 PolarHBondContact O-N 3.14Å
282	L	93.4	Very high	90.8	Very high	7 Å²	7	34.7 Å²	34.7	4%	0.037	20%	0.196	C	C	.	.	H	α-helix	trans	-61.3	-50.8	170.5	173.5	63.6	0	0	0	109.6	S120 L123 L124 N278 L279 K284 A285 L286	S120-L282 WeakPolarHBondContact O-CD1 3.3Å; L123-L282 HydrophobicContact CB-CB 4.26Å; L123-L282 HydrophobicContact CD1-CB 4.5Å; L124-L282 HydrophobicContact CB-CD1 4.41Å; L124-L282 HydrophobicContact CB-CD2 3.88Å; L124-L282 HydrophobicContact CD1-CD2 3.71Å; L124-L282 HydrophobicContact CG-CD2 4.27Å; N278-L282 VanDerWaalsContact O-CB 3.29Å; N278-L282 WeakPolarHBondContact O-CB 3.2Å; N278-L282 PolarHBondContact O-N 2.55Å; L279-L282 HydrophobicContact CD1-CD2 4.29Å; L279-L282 PolarHBondContact O-N 3.06Å; L282-K284 VanDerWaalsContact C-N 3.29Å; L282-K284 PolarHBondContact O-N 3.19Å; L282-A285 PolarHBondContact O-N 3.06Å; L282-A285 VanDerWaalsContact O-N 3.14Å; L282-L286 HydrophobicContact CD1-CD1 4.04Å; L282-L286 HydrophobicContact CD1-CG 4.12Å; L282-L286 HydrophobicContact CG-CD1 4.03Å; L282-L286 HydrophobicContact CG-CG 4.48Å; L282-L286 VanDerWaalsContact O-CG 3.28Å; L282-L286 WeakPolarHBondContact O-CG 3.45Å; L282-L286 PolarHBondContact O-N 3.41Å
283	A	92.2	Very high	91.3	Very high	47 Å²	47	29 Å²	29	39%	0.388	17%	0.166	S	C	.	.	H	α-helix	trans	-56.4	-45.5	175.7	0	0	0	0	0	111.2	L279 C280 A285 L286 L287	L279-A283 PolarHBondContact O-N 3.5Å; C280-A283 PolarHBondContact O-N 3.28Å; A283-A285 PolarHBondContact O-N 3.3Å; A283-L286 PolarHBondContact O-N 3.32Å; A283-L287 WeakPolarHBondContact O-CB 3.13Å; A283-L287 WeakPolarHBondContact O-CG 3.28Å; A283-L287 PolarHBondContact O-N 3.14Å
284	K	91.6	Very high	91.9	Very high	1 Å²	1	27 Å²	27	0%	0.004	15%	0.153	C	C	.	.	H	α-helix	trans	-57.8	-48.3	174.6	-179.7	-165.4	162.3	-168	0	112.2	G18 I19 H169 I172 C280 L281 L282 L286 L287 S288	G18-K284 WeakPolarHBondContact O-CE 3.36Å; G18-K284 PolarHBondContact O-NZ 3.09Å; I19-K284 HydrophobicContact CD1-CD 4.43Å; H169-K284 HydrophobicContact CB-CD 4.09Å; H169-K284 PolarHBondContact ND1-NZ 3.44Å; I172-K284 HydrophobicContact CD1-CB 4.44Å; I172-K284 HydrophobicContact CD1-CD 4.35Å; C280-K284 WeakPolarHBondContact O-CB 3.36Å; C280-K284 PolarHBondContact O-N 3.02Å; L281-K284 HydrophobicContact CD2-CD 3.96Å; L281-K284 WeakPolarHBondContact O-CB 3.49Å; L281-K284 PolarHBondContact O-N 2.82Å; L282-K284 VanDerWaalsContact C-N 3.29Å; L282-K284 PolarHBondContact O-N 3.19Å; K284-L286 VanDerWaalsContact C-N 3.35Å; K284-L286 PolarHBondContact O-N 2.96Å; K284-L287 PolarHBondContact O-N 3.3Å; K284-S288 VanDerWaalsContact O-CB 3.25Å; K284-S288 WeakPolarHBondContact O-CB 3.38Å; K284-S288 PolarHBondContact O-N 2.98Å
285	A	93.4	Very high	92.2	Very high	0 Å²	0	24.1 Å²	24.1	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-59	-46.2	179	0	0	0	0	0	111.4	I19 Y116 L281 L282 A283 L287 S288 Y289	I19-A285 HydrophobicContact CB-CB 4.36Å; I19-A285 HydrophobicContact CD1-CB 4.05Å; I19-A285 HydrophobicContact CG1-CB 4.08Å; Y116-A285 HydrophobicContact CD1-CB 4.04Å; Y116-A285 WeakPolarHBondContact CD1-O 3.46Å; L281-A285 WeakPolarHBondContact O-CB 3.3Å; L281-A285 PolarHBondContact O-N 3.14Å; L282-A285 PolarHBondContact O-N 3.06Å; L282-A285 VanDerWaalsContact O-N 3.14Å; A283-A285 PolarHBondContact O-N 3.3Å; A285-L287 PolarHBondContact O-N 3.28Å; A285-S288 PolarHBondContact O-N 3.45Å; A285-Y289 PolarHBondContact O-N 2.89Å
286	L	93.6	Very high	92.6	Very high	30 Å²	30	22 Å²	22	16%	0.157	13%	0.132	C	C	.	.	H	α-helix	trans	-64.8	-36.8	177.9	-64.8	174.1	0	0	0	112.7	F145 L146 L282 A283 K284 S288 P290	F145-L286 HydrophobicContact CB-CD1 3.91Å; F145-L286 HydrophobicContact CB-CD2 4Å; F145-L286 HydrophobicContact CD2-CD1 4.18Å; F145-L286 HydrophobicContact CG-CD1 4.04Å; L146-L286 HydrophobicContact CD1-CD2 4.27Å; L146-L286 HydrophobicContact CD2-CB 4.45Å; L146-L286 HydrophobicContact CD2-CD2 3.6Å; L146-L286 HydrophobicContact CG-CD2 3.77Å; L282-L286 HydrophobicContact CD1-CD1 4.04Å; L282-L286 HydrophobicContact CD1-CG 4.12Å; L282-L286 HydrophobicContact CG-CD1 4.03Å; L282-L286 HydrophobicContact CG-CG 4.48Å; L282-L286 VanDerWaalsContact O-CG 3.28Å; L282-L286 WeakPolarHBondContact O-CG 3.45Å; L282-L286 PolarHBondContact O-N 3.41Å; A283-L286 PolarHBondContact O-N 3.32Å; K284-L286 VanDerWaalsContact C-N 3.35Å; K284-L286 PolarHBondContact O-N 2.96Å; L286-S288 VanDerWaalsContact C-N 3.31Å; L286-P290 WeakPolarHBondContact O-CD 3.32Å
287	L	92.4	Very high	93	Very high	34 Å²	34	17.3 Å²	17.3	18%	0.178	10%	0.103	C	C	.	.	H	α-helix	trans	-73.3	-24	175.6	-69.4	171.1	0	0	0	113.2	L161 L164 C165 A283 K284 A285 P290	L161-L287 HydrophobicContact CD2-CD2 3.61Å; L164-L287 HydrophobicContact CB-CD1 4.23Å; L164-L287 HydrophobicContact CD2-CD1 3.63Å; L164-L287 HydrophobicContact CD2-CD2 3.94Å; L164-L287 HydrophobicContact CD2-CG 4.45Å; L164-L287 HydrophobicContact CG-CD1 3.68Å; C165-L287 HydrophobicContact CB-CB 4.01Å; A283-L287 WeakPolarHBondContact O-CB 3.13Å; A283-L287 WeakPolarHBondContact O-CG 3.28Å; A283-L287 PolarHBondContact O-N 3.14Å; K284-L287 PolarHBondContact O-N 3.3Å; A285-L287 PolarHBondContact O-N 3.28Å; L287-P290 WeakPolarHBondContact O-CD 3.28Å
288	S	93.7	Very high	93.2	Very high	1 Å²	1	19.2 Å²	19.2	1%	0.007	11%	0.111	C	C	.	.	H	α-helix	trans	-87	-34.6	-178.2	-163.6	0	0	0	0	112.6	N14 Y116 K284 A285 L286 L291 P292	N14-S288 PolarHBondContact ND2-O 3.26Å; N14-S288 VanDerWaalsContact OD1-CB 3.28Å; N14-S288 WeakPolarHBondContact OD1-CB 3.46Å; N14-S288 PolarHBondContact OD1-OG 3.46Å; Y116-S288 VanDerWaalsContact CZ-OG 3.32Å; Y116-S288 PolarHBondContact OH-OG 3.3Å; K284-S288 VanDerWaalsContact O-CB 3.25Å; K284-S288 WeakPolarHBondContact O-CB 3.38Å; K284-S288 PolarHBondContact O-N 2.98Å; A285-S288 PolarHBondContact O-N 3.45Å; L286-S288 VanDerWaalsContact C-N 3.31Å; S288-L291 PolarHBondContact O-N 2.88Å; S288-P292 WeakPolarHBondContact O-CD 3.34Å
289	Y	95.2	Very high	93.3	Very high	1 Å²	1	20.4 Å²	20.4	0%	0.004	12%	0.117	C	C	.	.	T	Hydrogen-bonded Turn	trans	-48.8	-41.3	177.5	-178.7	-83.4	0	0	0	115.9	C113 Y116 L117 L146 C149 A285 L291 P292 F293 L334 S337	C113-Y289 HydrophobicContact CB-CD2 4.38Å; C113-Y289 HydrophobicContact CB-CE2 3.57Å; C113-Y289 WeakPolarHBondContact O-CE2 3.47Å; Y116-Y289 HydrophobicContact CD2-CD2 4.43Å; Y116-Y289 HydrophobicContact CG-CD2 4.3Å; L117-Y289 HydrophobicContact CD1-CE2 4.2Å; L117-Y289 HydrophobicContact CG-CE2 4.22Å; L146-Y289 HydrophobicContact CB-CD1 4.47Å; L146-Y289 HydrophobicContact CB-CE1 4.37Å; L146-Y289 HydrophobicContact CD1-CD1 4.06Å; L146-Y289 HydrophobicContact CD1-CD2 3.71Å; L146-Y289 HydrophobicContact CD1-CE1 4.18Å; L146-Y289 HydrophobicContact CD1-CE2 3.84Å; L146-Y289 HydrophobicContact CD1-CG 3.85Å; L146-Y289 HydrophobicContact CD2-CD1 3.64Å; L146-Y289 HydrophobicContact CD2-CD2 4.39Å; L146-Y289 HydrophobicContact CD2-CE1 4.35Å; L146-Y289 HydrophobicContact CD2-CG 3.68Å; L146-Y289 HydrophobicContact CG-CD1 4.27Å; L146-Y289 HydrophobicContact CG-CG 4.36Å; C149-Y289 HydrophobicContact CB-CE1 4.4Å; A285-Y289 PolarHBondContact O-N 2.89Å; Y289-L291 PolarHBondContact O-N 2.86Å; Y289-L291 VanDerWaalsContact O-N 3.1Å; Y289-P292 WeakPolarHBondContact O-CD 3.16Å; Y289-P292 WeakPolarHBondContact O-CG 3.4Å; Y289-F293 HydrophobicContact CD1-CB 3.9Å; Y289-F293 HydrophobicContact CD1-CG 4.38Å; Y289-F293 HydrophobicContact CE1-CB 3.51Å; Y289-F293 HydrophobicContact CE1-CD1 4.49Å; Y289-F293 AromaticContact CE1-CD2 3.63Å; Y289-F293 HydrophobicContact CE1-CD2 3.63Å; Y289-F293 HydrophobicContact CE1-CE2 4.5Å; Y289-F293 AromaticContact CE1-CG 3.61Å; Y289-F293 HydrophobicContact CE1-CG 3.61Å; Y289-F293 AromaticContact CZ-CD2 3.81Å; Y289-F293 WeakPolarHBondContact O-CB 3.42Å; Y289-F293 PolarHBondContact O-N 3.39Å; Y289-F293 WeakPolarHBondContact OH-CD2 3.5Å; Y289-L334 HydrophobicContact CE1-CD1 4.32Å; Y289-L334 WeakPolarHBondContact OH-CD1 2.9Å; Y289-S337 PolarHBondContact OH-OG 3.42Å
290	P	95	Very high	93.4	Very high	4 Å²	4	17.4 Å²	17.4	3%	0.026	10%	0.101	C	C	.	.	H	α-helix	trans	-50.4	-35.6	179.3	-34.3	37.3	0	0	0	115.2	L152 V158 L161 L286 L287 Y294	L152-P290 HydrophobicContact CD1-CB 3.69Å; L152-P290 HydrophobicContact CD1-CG 4.25Å; V158-P290 HydrophobicContact CG1-CB 4.4Å; V158-P290 HydrophobicContact CG2-CB 4.43Å; L161-P290 HydrophobicContact CD1-CB 4.1Å; L161-P290 HydrophobicContact CD1-CG 3.78Å; L286-P290 WeakPolarHBondContact O-CD 3.32Å; L287-P290 WeakPolarHBondContact O-CD 3.28Å; P290-Y294 WeakPolarHBondContact O-CB 3.22Å; P290-Y294 PolarHBondContact O-N 2.74Å
291	L	93.9	Very high	93.5	Very high	5 Å²	5	16.1 Å²	16.1	3%	0.026	9%	0.09	C	C	.	.	H	α-helix	trans	-67.3	-58.9	-174.9	178.6	67.2	0	0	0	113.2	N11 N14 A15 V158 F217 S288 Y289 F293 Y294 A295	N11-L291 HydrophobicContact CB-CD1 4.38Å; N11-L291 WeakPolarHBondContact O-CD2 3.11Å; N14-L291 HydrophobicContact CB-CD2 4.06Å; A15-L291 HydrophobicContact CB-CD2 4.07Å; V158-L291 HydrophobicContact CG1-CB 3.85Å; V158-L291 HydrophobicContact CG1-CD1 3.78Å; V158-L291 HydrophobicContact CG1-CG 4.45Å; F217-L291 HydrophobicContact CD1-CD1 4.25Å; F217-L291 HydrophobicContact CD1-CG 4.31Å; F217-L291 HydrophobicContact CE1-CD1 4.24Å; F217-L291 HydrophobicContact CE1-CG 3.89Å; F217-L291 HydrophobicContact CZ-CG 4.25Å; S288-L291 PolarHBondContact O-N 2.88Å; Y289-L291 PolarHBondContact O-N 2.86Å; Y289-L291 VanDerWaalsContact O-N 3.1Å; L291-F293 VanDerWaalsContact C-N 3.3Å; L291-F293 PolarHBondContact O-N 3.49Å; L291-Y294 PolarHBondContact O-N 3.18Å; L291-A295 PolarHBondContact O-N 3.34Å; L291-A295 VanDerWaalsContact O-N 3.1Å
292	P	95.7	Very high	93.3	Very high	6 Å²	6	19 Å²	19	4%	0.039	11%	0.108	C	C	.	.	H	α-helix	trans	-64.5	-34.5	175.9	25.6	-35.3	0	0	0	112.4	L109 T112 Y116 F217 S288 Y289 A295 T296	L109-P292 HydrophobicContact CD2-CB 3.92Å; T112-P292 HydrophobicContact CG2-CB 3.8Å; T112-P292 HydrophobicContact CG2-CG 3.85Å; Y116-P292 HydrophobicContact CD2-CG 4.22Å; Y116-P292 HydrophobicContact CE2-CG 3.96Å; F217-P292 HydrophobicContact CZ-CB 4.34Å; S288-P292 WeakPolarHBondContact O-CD 3.34Å; Y289-P292 WeakPolarHBondContact O-CD 3.16Å; Y289-P292 WeakPolarHBondContact O-CG 3.4Å; P292-A295 PolarHBondContact O-N 2.89Å; P292-T296 PolarHBondContact O-N 3.35Å; P292-T296 PolarHBondContact O-OG1 2.8Å
293	F	96.3	Very high	93	Very high	0 Å²	0	20.2 Å²	20.2	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-61.6	-49.4	176.7	-179.4	-97.2	0	0	0	111.6	C149 L150 Y289 L291 A295 T296 A297 R330 L333 L334	C149-F293 HydrophobicContact CB-CD1 3.74Å; C149-F293 HydrophobicContact CB-CE1 3.9Å; C149-F293 HydrophobicContact CB-CG 4.39Å; C149-F293 VanDerWaalsContact O-CE1 3.31Å; C149-F293 WeakPolarHBondContact O-CE1 3.49Å; L150-F293 HydrophobicContact CD2-CZ 3.96Å; Y289-F293 HydrophobicContact CD1-CB 3.9Å; Y289-F293 HydrophobicContact CD1-CG 4.38Å; Y289-F293 HydrophobicContact CE1-CB 3.51Å; Y289-F293 HydrophobicContact CE1-CD1 4.49Å; Y289-F293 AromaticContact CE1-CD2 3.63Å; Y289-F293 HydrophobicContact CE1-CD2 3.63Å; Y289-F293 HydrophobicContact CE1-CE2 4.5Å; Y289-F293 AromaticContact CE1-CG 3.61Å; Y289-F293 HydrophobicContact CE1-CG 3.61Å; Y289-F293 AromaticContact CZ-CD2 3.81Å; Y289-F293 WeakPolarHBondContact O-CB 3.42Å; Y289-F293 PolarHBondContact O-N 3.39Å; Y289-F293 WeakPolarHBondContact OH-CD2 3.5Å; L291-F293 VanDerWaalsContact C-N 3.3Å; L291-F293 PolarHBondContact O-N 3.49Å; F293-A295 PolarHBondContact O-N 3.42Å; F293-T296 PolarHBondContact O-N 3.42Å; F293-A297 VanDerWaalsContact O-CB 3.3Å; F293-A297 WeakPolarHBondContact O-CB 3.31Å; F293-A297 PolarHBondContact O-N 3.5Å; F293-R330 HydrophobicContact CE1-CB 4.48Å; F293-R330 HydrophobicContact CE1-CG 4.49Å; F293-R330 HydrophobicContact CZ-CB 4Å; F293-R330 HydrophobicContact CZ-CG 4.38Å; F293-R330 WeakPolarHBondContact CZ-O 3.42Å; F293-L333 HydrophobicContact CD2-CD2 3.65Å; F293-L333 HydrophobicContact CD2-CG 4.04Å; F293-L333 HydrophobicContact CE2-CB 4.16Å; F293-L333 HydrophobicContact CE2-CD2 3.56Å; F293-L333 HydrophobicContact CE2-CG 3.77Å; F293-L333 HydrophobicContact CG-CD2 4.42Å; F293-L333 HydrophobicContact CZ-CD2 4.24Å; F293-L334 HydrophobicContact CE2-CB 3.98Å; F293-L334 HydrophobicContact CZ-CB 4.49Å
294	Y	93.8	Very high	92.7	Very high	28 Å²	28	22.9 Å²	22.9	11%	0.11	12%	0.123	C	C	.	.	H	α-helix	trans	-58	-49.8	176.7	176.5	-92	0	0	0	111.4	L152 T153 L155 V158 P290 L291 T296 A297 E298	L152-Y294 WeakPolarHBondContact O-CD2 3.46Å; T153-Y294 WeakPolarHBondContact O-CE2 3.16Å; T153-Y294 PolarHBondContact O-OH 2.84Å; L155-Y294 HydrophobicContact CD1-CE1 4Å; L155-Y294 HydrophobicContact CD2-CD1 3.41Å; L155-Y294 VanDerWaalsContact CD2-CD1 3.41Å; L155-Y294 HydrophobicContact CD2-CE1 3.3Å; L155-Y294 HydrophobicContact CD2-CG 4.34Å; L155-Y294 HydrophobicContact CG-CD1 3.99Å; L155-Y294 HydrophobicContact CG-CE1 3.33Å; V158-Y294 HydrophobicContact CG2-CG 4.34Å; P290-Y294 WeakPolarHBondContact O-CB 3.22Å; P290-Y294 PolarHBondContact O-N 2.74Å; L291-Y294 PolarHBondContact O-N 3.18Å; Y294-T296 VanDerWaalsContact C-N 3.34Å; Y294-T296 PolarHBondContact O-N 3.47Å; Y294-A297 PolarHBondContact O-N 3.08Å; Y294-E298 HydrophobicContact CD1-CG 4.24Å; Y294-E298 HydrophobicContact CE1-CG 3.72Å; Y294-E298 HydrophobicContact CE2-CG 4.03Å; Y294-E298 WeakPolarHBondContact O-CG 3.27Å; Y294-E298 PolarHBondContact O-N 2.94Å
295	A	94.1	Very high	92.3	Very high	16 Å²	16	24.8 Å²	24.8	13%	0.132	13%	0.133	C	C	.	.	H	α-helix	trans	-60.4	-42.7	-179	0	0	0	0	0	112.4	L109 F217 L291 P292 F293 E298 I299	L109-A295 HydrophobicContact CD1-CB 3.88Å; L109-A295 HydrophobicContact CD2-CB 4.48Å; F217-A295 HydrophobicContact CD1-CB 3.95Å; F217-A295 HydrophobicContact CE1-CB 3.52Å; L291-A295 PolarHBondContact O-N 3.34Å; L291-A295 VanDerWaalsContact O-N 3.1Å; P292-A295 PolarHBondContact O-N 2.89Å; F293-A295 PolarHBondContact O-N 3.42Å; A295-E298 PolarHBondContact O-N 3.43Å; A295-I299 WeakPolarHBondContact O-CG1 3.34Å; A295-I299 PolarHBondContact O-N 3.36Å; A295-I299 VanDerWaalsContact O-N 3.15Å
296	T	96	Very high	90.9	Very high	0 Å²	0	32.7 Å²	32.7	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-66	-43.4	177.9	-43.1	0	0	0	0	111.3	V106 L109 P292 F293 Y294 E298 I299 L300 L333	V106-T296 HydrophobicContact CB-CG2 4.36Å; V106-T296 HydrophobicContact CG1-CG2 4.02Å; V106-T296 HydrophobicContact CG2-CG2 4.22Å; L109-T296 HydrophobicContact CB-CG2 4.34Å; L109-T296 WeakPolarHBondContact CB-OG1 3.27Å; L109-T296 WeakPolarHBondContact CD1-OG1 3.48Å; P292-T296 PolarHBondContact O-N 3.35Å; P292-T296 PolarHBondContact O-OG1 2.8Å; F293-T296 PolarHBondContact O-N 3.42Å; Y294-T296 VanDerWaalsContact C-N 3.34Å; Y294-T296 PolarHBondContact O-N 3.47Å; T296-E298 VanDerWaalsContact C-N 3.29Å; T296-E298 PolarHBondContact O-N 3.36Å; T296-I299 PolarHBondContact O-N 3.31Å; T296-L300 WeakPolarHBondContact O-CB 3.33Å; T296-L300 PolarHBondContact O-N 2.85Å; T296-L333 HydrophobicContact CG2-CD1 3.65Å; T296-L333 HydrophobicContact CG2-CD2 3.95Å; T296-L333 HydrophobicContact CG2-CG 4.47Å
297	A	93.8	Very high	88.9	Confident	0 Å²	0	39.4 Å²	39.4	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-61	-39.9	179.9	0	0	0	0	0	111.3	F293 Y294 Q301 R330 L333	F293-A297 VanDerWaalsContact O-CB 3.3Å; F293-A297 WeakPolarHBondContact O-CB 3.31Å; F293-A297 PolarHBondContact O-N 3.5Å; Y294-A297 PolarHBondContact O-N 3.08Å; A297-Q301 VanDerWaalsContact O-CB 3.28Å; A297-Q301 WeakPolarHBondContact O-CB 3.42Å; A297-Q301 WeakPolarHBondContact O-CG 3.46Å; A297-Q301 PolarHBondContact O-N 2.78Å; A297-Q301 PolarHBondContact O-NE2 3.47Å; A297-R330 HydrophobicContact CB-CG 3.79Å; A297-L333 HydrophobicContact CB-CD2 4.15Å
298	E	91.1	Very high	86.6	Confident	62 Å²	62	43.4 Å²	43.4	29%	0.29	22%	0.215	S	C	.	.	H	α-helix	trans	-68.1	-41.9	177.3	-71.2	-56.3	108.4	0	0	112.5	Y294 A295 T296 Q301 T302 R330	Y294-E298 HydrophobicContact CD1-CG 4.24Å; Y294-E298 HydrophobicContact CE1-CG 3.72Å; Y294-E298 HydrophobicContact CE2-CG 4.03Å; Y294-E298 WeakPolarHBondContact O-CG 3.27Å; Y294-E298 PolarHBondContact O-N 2.94Å; A295-E298 PolarHBondContact O-N 3.43Å; T296-E298 VanDerWaalsContact C-N 3.29Å; T296-E298 PolarHBondContact O-N 3.36Å; E298-Q301 PolarHBondContact OE1-NE2 3.3Å; E298-T302 WeakPolarHBondContact O-CB 3.32Å; E298-T302 PolarHBondContact O-N 3.45Å; E298-T302 PolarHBondContact O-OG1 3.4Å; E298-R330 IonicContact OE1-NH2 3.03Å; E298-R330 PolarHBondContact OE1-NH2 3.48Å
299	I	92.7	Very high	84.2	Confident	26 Å²	26	46.4 Å²	46.4	13%	0.133	24%	0.24	C	C	.	.	H	α-helix	trans	-61.8	-47.5	175.3	-65.2	166.9	0	0	0	110	N102 Q105 V106 L109 A295 T296 T302 C303	N102-I299 HydrophobicContact CB-CG2 4.17Å; Q105-I299 HydrophobicContact CB-CD1 3.8Å; Q105-I299 HydrophobicContact CG-CD1 4.49Å; V106-I299 HydrophobicContact CG2-CB 4.34Å; V106-I299 HydrophobicContact CG2-CG2 3.75Å; L109-I299 HydrophobicContact CD1-CD1 4.03Å; A295-I299 WeakPolarHBondContact O-CG1 3.34Å; A295-I299 PolarHBondContact O-N 3.36Å; A295-I299 VanDerWaalsContact O-N 3.15Å; T296-I299 PolarHBondContact O-N 3.31Å; I299-T302 PolarHBondContact O-N 3.1Å; I299-C303 PolarHBondContact O-N 3.31Å; I299-C303 PolarHBondContact O-SG 2.99Å
300	L	93	Very high	81.4	Confident	40 Å²	40	51.2 Å²	51.2	21%	0.209	27%	0.274	C	S	.	.	H	α-helix	trans	-68.1	-40.4	-176.7	-167.7	59.8	0	0	0	112.1	T296 T302 C303 L304 V329	T296-L300 WeakPolarHBondContact O-CB 3.33Å; T296-L300 PolarHBondContact O-N 2.85Å; L300-T302 VanDerWaalsContact C-N 3.33Å; L300-T302 PolarHBondContact O-N 2.84Å; L300-C303 PolarHBondContact O-N 3.26Å; L300-L304 HydrophobicContact CD1-CD1 3.63Å; L300-L304 HydrophobicContact CD1-CG 3.9Å; L300-L304 HydrophobicContact CD2-CD1 4.39Å; L300-L304 HydrophobicContact CG-CD1 3.7Å; L300-L304 HydrophobicContact CG-CG 4.25Å; L300-L304 WeakPolarHBondContact O-CB 3.43Å; L300-L304 WeakPolarHBondContact O-CG 3.43Å; L300-L304 PolarHBondContact O-N 3.4Å; L300-V329 HydrophobicContact CB-CG1 3.96Å; L300-V329 HydrophobicContact CD2-CG1 3.53Å; L300-V329 HydrophobicContact CG-CG1 3.62Å
301	Q	91.1	Very high	78.8	Confident	29 Å²	29	58.7 Å²	58.7	14%	0.136	31%	0.313	C	S	.	.	H	α-helix	trans	-60.1	-43.7	171.8	-76.1	170.7	73.3	0	0	111.4	A297 E298 C303 L304 L305 T326 V329 R330	A297-Q301 VanDerWaalsContact O-CB 3.28Å; A297-Q301 WeakPolarHBondContact O-CB 3.42Å; A297-Q301 WeakPolarHBondContact O-CG 3.46Å; A297-Q301 PolarHBondContact O-N 2.78Å; A297-Q301 PolarHBondContact O-NE2 3.47Å; E298-Q301 PolarHBondContact OE1-NE2 3.3Å; Q301-C303 VanDerWaalsContact C-N 3.28Å; Q301-C303 PolarHBondContact O-N 3.44Å; Q301-L304 PolarHBondContact O-N 2.87Å; Q301-L305 HydrophobicContact CB-CD1 4.33Å; Q301-L305 HydrophobicContact CG-CD1 4.13Å; Q301-L305 WeakPolarHBondContact O-CA 3.22Å; Q301-L305 VanDerWaalsContact O-CB 3.3Å; Q301-L305 WeakPolarHBondContact O-CB 3.41Å; Q301-L305 PolarHBondContact O-N 2.92Å; Q301-T326 HydrophobicContact CG-CG2 4.36Å; Q301-T326 PolarHBondContact OE1-OG1 2.85Å; Q301-V329 HydrophobicContact CG-CG1 4.25Å; Q301-R330 VanDerWaalsContact NE2-NE 3.2Å
302	T	87.3	Confident	76	Confident	63 Å²	63	62.3 Å²	62.3	39%	0.387	34%	0.339	S	S	.	.	H	α-helix	trans	-66.1	-30	177.6	-55.8	0	0	0	0	112.3	E298 I299 L300 R306	E298-T302 WeakPolarHBondContact O-CB 3.32Å; E298-T302 PolarHBondContact O-N 3.45Å; E298-T302 PolarHBondContact O-OG1 3.4Å; I299-T302 PolarHBondContact O-N 3.1Å; L300-T302 VanDerWaalsContact C-N 3.33Å; L300-T302 PolarHBondContact O-N 2.84Å; T302-R306 WeakPolarHBondContact O-CB 3.35Å; T302-R306 WeakPolarHBondContact O-CD 3.36Å
303	C	87.1	Confident	73	Confident	31 Å²	31	66.1 Å²	66.1	21%	0.209	37%	0.366	C	S	.	.	H	α-helix	trans	-81.4	-37.5	177.9	-64.9	0	0	0	0	112.8	W99 I299 L300 Q301	W99-C303 HydrophobicContact CH2-CB 4.16Å; W99-C303 HydrophobicContact CZ3-CB 4.22Å; I299-C303 PolarHBondContact O-N 3.31Å; I299-C303 PolarHBondContact O-SG 2.99Å; L300-C303 PolarHBondContact O-N 3.26Å; Q301-C303 VanDerWaalsContact C-N 3.28Å; Q301-C303 PolarHBondContact O-N 3.44Å
304	L	86.3	Confident	70.3	Confident	103 Å²	103	72.2 Å²	72.2	54%	0.539	41%	0.405	S	S	.	.	H	α-helix	trans	-96.8	-30.5	-171.7	-62.7	-179	0	0	0	114.3	L300 Q301 V329	L300-L304 HydrophobicContact CD1-CD1 3.63Å; L300-L304 HydrophobicContact CD1-CG 3.9Å; L300-L304 HydrophobicContact CD2-CD1 4.39Å; L300-L304 HydrophobicContact CG-CD1 3.7Å; L300-L304 HydrophobicContact CG-CG 4.25Å; L300-L304 WeakPolarHBondContact O-CB 3.43Å; L300-L304 WeakPolarHBondContact O-CG 3.43Å; L300-L304 PolarHBondContact O-N 3.4Å; Q301-L304 PolarHBondContact O-N 2.87Å; L304-V329 HydrophobicContact CD1-CG2 4.18Å
305	L	82.3	Confident	67.4	Low	42 Å²	42	75.5 Å²	75.5	22%	0.22	43%	0.432	C	S	.	.	S	Bend	trans	-110.6	-2.8	-170.5	-54.2	178.6	0	0	0	113.5	Q301 E307 D308 P325 V329	Q301-L305 HydrophobicContact CB-CD1 4.33Å; Q301-L305 HydrophobicContact CG-CD1 4.13Å; Q301-L305 WeakPolarHBondContact O-CA 3.22Å; Q301-L305 VanDerWaalsContact O-CB 3.3Å; Q301-L305 WeakPolarHBondContact O-CB 3.41Å; Q301-L305 PolarHBondContact O-N 2.92Å; L305-E307 PolarHBondContact O-N 3.28Å; L305-D308 PolarHBondContact O-N 3.38Å; L305-P325 HydrophobicContact CD1-CB 4.23Å; L305-P325 HydrophobicContact CD2-CB 3.92Å; L305-V329 HydrophobicContact CD1-CG2 4.42Å
306	R	64.5	Low	64.5	Low	165 Å²	165	83.4 Å²	83.4	62%	0.623	46%	0.463	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.1	-15.1	-175.6	-177.6	169.8	-172.6	170.7	0.5	114.1	T302	T302-R306 WeakPolarHBondContact O-CB 3.35Å; T302-R306 WeakPolarHBondContact O-CD 3.36Å
307	E	50.7	Low	62	Low	171 Å²	171	90.9 Å²	90.9	80%	0.799	50%	0.503	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.1	-29	173.5	-115.9	174.5	158	0	0	113.1	L305 S310	L305-E307 PolarHBondContact O-N 3.28Å; E307-S310 PolarHBondContact O-OG 3.29Å
308	D	45.3	Very low	59.3	Low	118 Å²	118	102 Å²	102	63%	0.631	55%	0.545	S	S	*	.	G	3₁₀ helix	trans	-83	-18.2	-176.5	-71.7	-31.1	0	0	0	113.7	L305 L311	L305-D308 PolarHBondContact O-N 3.38Å; D308-L311 PolarHBondContact O-N 2.98Å
309	A	43.3	Very low	56.9	Low	64 Å²	64	105.8 Å²	105.8	53%	0.529	57%	0.572	S	S	.	*	G	3₁₀ helix	trans	-79.4	-18.7	-175.1	0	0	0	0	0	113.8	L311 S312	A309-L311 PolarHBondContact O-N 2.97Å; A309-S312 PolarHBondContact O-N 3.09Å
310	S	35.6	Very low	54.8	Low	103 Å²	103	112.6 Å²	112.6	72%	0.72	60%	0.603	S	S	*	*	G	3₁₀ helix	trans	-71	-9.9	173	38.7	0	0	0	0	114	E307	E307-S310 PolarHBondContact O-OG 3.29Å
311	L	40.6	Very low	53.3	Low	161 Å²	161	114.1 Å²	114.1	84%	0.843	63%	0.629	S	S	*	*	G	3₁₀ helix	trans	-104	-6.6	176.5	-88.6	85.3	0	0	0	114.4	D308 A309	D308-L311 PolarHBondContact O-N 2.98Å; A309-L311 PolarHBondContact O-N 2.97Å
312	S	34.8	Very low	52.4	Low	81 Å²	81	115 Å²	115	57%	0.566	64%	0.636	S	S	*	*	S	Bend	trans	-125.5	113	-175.5	50.4	0	0	0	0	112.7	A309	A309-S312 PolarHBondContact O-N 3.09Å
313	S	32.6	Very low	52.2	Low	86 Å²	86	114.6 Å²	114.6	60%	0.601	64%	0.636	S	S	*	*			trans	-50.5	138.2	178.3	178.4	0	0	0	0	112.9	S315	S313-S315 PolarHBondContact O-N 3.4Å; S313-S315 PolarHBondContact OG-OG 3.05Å
314	P	40.5	Very low	52.1	Low	127 Å²	127	117.5 Å²	117.5	83%	0.825	66%	0.655	S	S	*	*	T	Hydrogen-bonded Turn	trans	-69.5	2.6	-173.9	26.1	-33.5	0	0	0	115.2
315	S	32.8	Very low	52.1	Low	98 Å²	98	115.2 Å²	115.2	69%	0.685	65%	0.647	S	S	*	*	T	Hydrogen-bonded Turn	trans	-92	-3.6	-173	62.2	0	0	0	0	115.9	S313	S313-S315 PolarHBondContact O-N 3.4Å; S313-S315 PolarHBondContact OG-OG 3.05Å
316	K	33	Very low	52.4	Low	181 Å²	181	114.1 Å²	114.1	79%	0.787	64%	0.642	S	S	*	*	S	Bend	trans	-108.7	-5.3	-178.4	-71.1	-174.6	179.1	178.8	0	115.7	R318	K316-R318 PolarHBondContact O-N 2.9Å
317	L	43.8	Very low	53.7	Low	158 Å²	158	109.7 Å²	109.7	83%	0.827	63%	0.63	S	S	*	*	T	Hydrogen-bonded Turn	trans	-94.5	50.9	-172.3	-164.2	74.7	0	0	0	113
318	R	38.1	Very low	55.7	Low	234 Å²	234	107.8 Å²	107.8	88%	0.883	62%	0.623	S	S	*	*	T	Hydrogen-bonded Turn	trans	-128.9	-0.2	178.9	-162	161.1	148.1	-171.8	-8.9	114.8	K316	K316-R318 PolarHBondContact O-N 2.9Å
319	T	40.7	Very low	57.9	Low	140 Å²	140	102.9 Å²	102.9	86%	0.859	60%	0.597	S	S	*	*	S	Bend	trans	-147.5	30.5	-178	-26.7	0	0	0	0	114.2
320	Q	47.2	Very low	60.4	Low	169 Å²	169	99.9 Å²	99.9	79%	0.79	57%	0.572	S	S	*	*			trans	-124.5	136.2	174	-102.7	-179	-18	0	0	109.9
321	G	61.4	Low	63.2	Low	73 Å²	73	96.1 Å²	96.1	75%	0.753	55%	0.55	S	S	*	*			trans	-57.3	174.2	175.7	0	0	0	0	0	112.9	S323	G321-S323 PolarHBondContact O-N 3.3Å
322	V	72.3	Confident	65.8	Low	47 Å²	47	91.4 Å²	91.4	29%	0.285	53%	0.534	S	S	.	.			trans	-51.5	124.1	-179	-173.2	0	0	0	0	110.2	L151 T153 T326 L327	L151-V322 HydrophobicContact CD2-CG2 4.49Å; T153-V322 HydrophobicContact CG2-CG2 3.74Å; V322-T326 HydrophobicContact CG1-CG2 3.52Å; V322-L327 HydrophobicContact CG1-CB 4.29Å
323	S	83.6	Confident	68.7	Low	55 Å²	55	87.8 Å²	87.8	39%	0.385	51%	0.508	S	S	.	.			trans	-63.8	149.3	179.6	77.1	0	0	0	0	110.5	G321 P325 T326 L327	G321-S323 PolarHBondContact O-N 3.3Å; S323-P325 WeakPolarHBondContact OG-CG 3.46Å; S323-T326 PolarHBondContact O-N 3.14Å; S323-T326 VanDerWaalsContact O-N 3.15Å; S323-T326 WeakPolarHBondContact OG-CB 3.48Å; S323-T326 PolarHBondContact OG-N 3.46Å; S323-T326 PolarHBondContact OG-OG1 3.21Å; S323-L327 PolarHBondContact O-N 3.13Å
324	C	85.5	Confident	71.8	Confident	91 Å²	91	83.9 Å²	83.9	62%	0.615	48%	0.481	S	S	*	.	H	α-helix	trans	-51	-48.2	176.1	-169.7	0	0	0	0	113.4	T326 L327 M328	C324-T326 PolarHBondContact O-N 3.48Å; C324-L327 PolarHBondContact O-N 3.05Å; C324-M328 WeakPolarHBondContact O-CG 3.44Å; C324-M328 PolarHBondContact O-N 3.35Å
325	P	86.6	Confident	74.5	Confident	56 Å²	56	82.4 Å²	82.4	36%	0.364	47%	0.465	S	S	.	.	H	α-helix	trans	-64.4	-37.7	178.2	23.8	-33.4	0	0	0	112.9	L305 S323 L327 M328 V329	L305-P325 HydrophobicContact CD1-CB 4.23Å; L305-P325 HydrophobicContact CD2-CB 3.92Å; S323-P325 WeakPolarHBondContact OG-CG 3.46Å; P325-L327 VanDerWaalsContact C-N 3.33Å; P325-L327 PolarHBondContact O-N 2.73Å; P325-M328 PolarHBondContact O-N 3.32Å; P325-V329 WeakPolarHBondContact O-CG2 3.45Å; P325-V329 PolarHBondContact O-N 3.45Å
326	T	87.8	Confident	77.5	Confident	18 Å²	18	80 Å²	80	11%	0.11	45%	0.449	C	S	.	.	H	α-helix	trans	-61.4	-42.5	173.8	-66.5	0	0	0	0	111.4	Q301 V322 S323 C324 V329 R330	Q301-T326 HydrophobicContact CG-CG2 4.36Å; Q301-T326 PolarHBondContact OE1-OG1 2.85Å; V322-T326 HydrophobicContact CG1-CG2 3.52Å; S323-T326 PolarHBondContact O-N 3.14Å; S323-T326 VanDerWaalsContact O-N 3.15Å; S323-T326 WeakPolarHBondContact OG-CB 3.48Å; S323-T326 PolarHBondContact OG-N 3.46Å; S323-T326 PolarHBondContact OG-OG1 3.21Å; C324-T326 PolarHBondContact O-N 3.48Å; T326-V329 PolarHBondContact O-N 2.94Å; T326-R330 WeakPolarHBondContact O-CB 3.39Å; T326-R330 WeakPolarHBondContact O-CG 3.44Å; T326-R330 PolarHBondContact O-N 2.91Å; T326-R330 VanDerWaalsContact O-N 3.09Å
327	L	90.9	Very high	80.5	Confident	72 Å²	72	71.4 Å²	71.4	38%	0.377	41%	0.411	S	S	.	.	H	α-helix	trans	-66	-39	177.5	-171.6	65.3	0	0	0	111.8	L150 V322 S323 C324 P325 R330 G331	L150-L327 HydrophobicContact CB-CD1 3.84Å; L150-L327 HydrophobicContact CD1-CD1 4.38Å; V322-L327 HydrophobicContact CG1-CB 4.29Å; S323-L327 PolarHBondContact O-N 3.13Å; C324-L327 PolarHBondContact O-N 3.05Å; P325-L327 VanDerWaalsContact C-N 3.33Å; P325-L327 PolarHBondContact O-N 2.73Å; L327-R330 PolarHBondContact O-N 3.1Å; L327-G331 PolarHBondContact O-N 2.93Å
328	M	92.5	Very high	83	Confident	132 Å²	132	65.4 Å²	65.4	65%	0.65	38%	0.378	S	S	*	.	H	α-helix	trans	-63	-46	175.9	-71.8	179.5	73.1	0	0	112.1	C324 P325 R330 G331 A332	C324-M328 WeakPolarHBondContact O-CG 3.44Å; C324-M328 PolarHBondContact O-N 3.35Å; P325-M328 PolarHBondContact O-N 3.32Å; M328-R330 VanDerWaalsContact C-N 3.34Å; M328-R330 PolarHBondContact O-N 2.76Å; M328-G331 PolarHBondContact O-N 2.81Å; M328-A332 WeakPolarHBondContact O-CB 3.4Å; M328-A332 PolarHBondContact O-N 2.71Å
329	V	92.6	Very high	85.7	Confident	14 Å²	14	58.6 Å²	58.6	9%	0.085	36%	0.359	C	S	.	.	H	α-helix	trans	-60.1	-45.6	177.2	171.3	0	0	0	0	110.8	L300 Q301 L304 L305 P325 T326 A332 L333	L300-V329 HydrophobicContact CB-CG1 3.96Å; L300-V329 HydrophobicContact CD2-CG1 3.53Å; L300-V329 HydrophobicContact CG-CG1 3.62Å; Q301-V329 HydrophobicContact CG-CG1 4.25Å; L304-V329 HydrophobicContact CD1-CG2 4.18Å; L305-V329 HydrophobicContact CD1-CG2 4.42Å; P325-V329 WeakPolarHBondContact O-CG2 3.45Å; P325-V329 PolarHBondContact O-N 3.45Å; T326-V329 PolarHBondContact O-N 2.94Å; V329-A332 PolarHBondContact O-N 3.32Å; V329-L333 WeakPolarHBondContact O-CB 3.41Å; V329-L333 PolarHBondContact O-N 3.14Å
330	R	94.6	Very high	88.2	Confident	1 Å²	1	54.2 Å²	54.2	0%	0.004	33%	0.33	C	S	.	.	H	α-helix	trans	-65.9	-39.9	177.5	-73.4	170.6	174.2	-105.2	3.4	112.4	L150 L152 F293 A297 E298 Q301 T326 L327 M328 L333 L334	L150-R330 VanDerWaalsContact CD2-C 3.49Å; L150-R330 HydrophobicContact CD2-CB 3.85Å; L150-R330 WeakPolarHBondContact CD2-O 3.33Å; L150-R330 WeakPolarHBondContact O-CD 3.39Å; L152-R330 VanDerWaalsContact O-CZ 3.23Å; L152-R330 PolarHBondContact O-NH1 3.05Å; L152-R330 PolarHBondContact O-NH2 3.1Å; F293-R330 HydrophobicContact CE1-CB 4.48Å; F293-R330 HydrophobicContact CE1-CG 4.49Å; F293-R330 HydrophobicContact CZ-CB 4Å; F293-R330 HydrophobicContact CZ-CG 4.38Å; F293-R330 WeakPolarHBondContact CZ-O 3.42Å; A297-R330 HydrophobicContact CB-CG 3.79Å; E298-R330 IonicContact OE1-NH2 3.03Å; E298-R330 PolarHBondContact OE1-NH2 3.48Å; Q301-R330 VanDerWaalsContact NE2-NE 3.2Å; T326-R330 WeakPolarHBondContact O-CB 3.39Å; T326-R330 WeakPolarHBondContact O-CG 3.44Å; T326-R330 PolarHBondContact O-N 2.91Å; T326-R330 VanDerWaalsContact O-N 3.09Å; L327-R330 PolarHBondContact O-N 3.1Å; M328-R330 VanDerWaalsContact C-N 3.34Å; M328-R330 PolarHBondContact O-N 2.76Å; R330-L333 PolarHBondContact O-N 2.85Å; R330-L334 PolarHBondContact O-N 3.09Å
331	G	95.4	Very high	90.3	Very high	25 Å²	25	46.5 Å²	46.5	26%	0.258	29%	0.294	S	S	.	.	H	α-helix	trans	-64.4	-44	175.5	0	0	0	0	0	112.3	L327 M328 L333 L334 L335	L327-G331 PolarHBondContact O-N 2.93Å; M328-G331 PolarHBondContact O-N 2.81Å; G331-L333 VanDerWaalsContact C-N 3.34Å; G331-L333 PolarHBondContact O-N 3.25Å; G331-L334 PolarHBondContact O-N 3.46Å; G331-L335 VanDerWaalsContact O-CB 3.31Å; G331-L335 WeakPolarHBondContact O-CB 3.36Å; G331-L335 PolarHBondContact O-N 3.32Å
332	A	95.5	Very high	91.7	Very high	61 Å²	61	47.5 Å²	47.5	50%	0.504	28%	0.282	S	S	.	.	H	α-helix	trans	-63.8	-39.3	175.1	0	0	0	0	0	112	M328 V329 L335 S336	M328-A332 WeakPolarHBondContact O-CB 3.4Å; M328-A332 PolarHBondContact O-N 2.71Å; V329-A332 PolarHBondContact O-N 3.32Å; A332-L335 PolarHBondContact O-N 3.24Å; A332-S336 VanDerWaalsContact O-CB 3.28Å; A332-S336 WeakPolarHBondContact O-CB 3.28Å; A332-S336 PolarHBondContact O-N 3.45Å; A332-S336 PolarHBondContact O-OG 2.89Å
333	L	96.4	Very high	92.4	Very high	5 Å²	5	51.3 Å²	51.3	3%	0.026	30%	0.3	C	S	.	.	H	α-helix	trans	-61.6	-48.1	173.9	176	64.3	0	0	0	111.8	L110 F293 T296 A297 V329 R330 G331 S336 S337	L110-L333 HydrophobicContact CD1-CD1 3.74Å; F293-L333 HydrophobicContact CD2-CD2 3.65Å; F293-L333 HydrophobicContact CD2-CG 4.04Å; F293-L333 HydrophobicContact CE2-CB 4.16Å; F293-L333 HydrophobicContact CE2-CD2 3.56Å; F293-L333 HydrophobicContact CE2-CG 3.77Å; F293-L333 HydrophobicContact CG-CD2 4.42Å; F293-L333 HydrophobicContact CZ-CD2 4.24Å; T296-L333 HydrophobicContact CG2-CD1 3.65Å; T296-L333 HydrophobicContact CG2-CD2 3.95Å; T296-L333 HydrophobicContact CG2-CG 4.47Å; A297-L333 HydrophobicContact CB-CD2 4.15Å; V329-L333 WeakPolarHBondContact O-CB 3.41Å; V329-L333 PolarHBondContact O-N 3.14Å; R330-L333 PolarHBondContact O-N 2.85Å; G331-L333 VanDerWaalsContact C-N 3.34Å; G331-L333 PolarHBondContact O-N 3.25Å; L333-S336 WeakPolarHBondContact CA-OG 3.49Å; L333-S336 PolarHBondContact O-N 3Å; L333-S336 PolarHBondContact O-OG 3.23Å; L333-S337 PolarHBondContact O-N 2.97Å; L333-S337 PolarHBondContact O-OG 2.98Å
334	L	97	Very high	92.3	Very high	5 Å²	5	49.3 Å²	49.3	3%	0.026	29%	0.285	C	S	.	.	H	α-helix	trans	-65.5	-40.1	178.5	-179.9	62.2	0	0	0	112	L143 L146 L147 L150 Y289 F293 R330 G331 S337 Y338	L143-L334 HydrophobicContact CD1-CD1 3.84Å; L143-L334 HydrophobicContact CD1-CD2 3.88Å; L143-L334 HydrophobicContact CD1-CG 3.65Å; L146-L334 HydrophobicContact CB-CD1 4.29Å; L147-L334 HydrophobicContact CD1-CD2 4.06Å; L150-L334 HydrophobicContact CD2-CB 4.26Å; L150-L334 HydrophobicContact CD2-CD2 4.08Å; L150-L334 HydrophobicContact CG-CD2 4.28Å; Y289-L334 HydrophobicContact CE1-CD1 4.32Å; Y289-L334 WeakPolarHBondContact OH-CD1 2.9Å; F293-L334 HydrophobicContact CE2-CB 3.98Å; F293-L334 HydrophobicContact CZ-CB 4.49Å; R330-L334 PolarHBondContact O-N 3.09Å; G331-L334 PolarHBondContact O-N 3.46Å; L334-S337 PolarHBondContact O-OG 3.5Å; L334-Y338 VanDerWaalsContact O-CB 3.27Å; L334-Y338 WeakPolarHBondContact O-CB 3.39Å; L334-Y338 PolarHBondContact O-N 3.41Å
335	L	96.5	Very high	91.6	Very high	96 Å²	96	47.3 Å²	47.3	50%	0.503	27%	0.271	S	S	.	.	H	α-helix	trans	-68	-41.6	178.2	-177.9	61.5	0	0	0	111.5	G331 A332 Y338 L339	G331-L335 VanDerWaalsContact O-CB 3.31Å; G331-L335 WeakPolarHBondContact O-CB 3.36Å; G331-L335 PolarHBondContact O-N 3.32Å; A332-L335 PolarHBondContact O-N 3.24Å; L335-Y338 WeakPolarHBondContact O-CB 3.47Å; L335-Y338 PolarHBondContact O-N 3.45Å; L335-L339 HydrophobicContact CD1-CD1 4.46Å; L335-L339 HydrophobicContact CD1-CG 4.31Å; L335-L339 HydrophobicContact CG-CD1 4.21Å; L335-L339 HydrophobicContact CG-CG 4.47Å; L335-L339 VanDerWaalsContact O-CG 3.3Å; L335-L339 WeakPolarHBondContact O-CG 3.4Å; L335-L339 PolarHBondContact O-N 3.09Å
336	S	96.2	Very high	91.4	Very high	48 Å²	48	48.1 Å²	48.1	34%	0.336	27%	0.267	S	S	.	.	H	α-helix	trans	-66.8	-42.1	178.5	55.7	0	0	0	0	112.3	A332 L333 Y338 L339 L340	A332-S336 VanDerWaalsContact O-CB 3.28Å; A332-S336 WeakPolarHBondContact O-CB 3.28Å; A332-S336 PolarHBondContact O-N 3.45Å; A332-S336 PolarHBondContact O-OG 2.89Å; L333-S336 WeakPolarHBondContact CA-OG 3.49Å; L333-S336 PolarHBondContact O-N 3Å; L333-S336 PolarHBondContact O-OG 3.23Å; S336-Y338 VanDerWaalsContact C-N 3.3Å; S336-Y338 PolarHBondContact O-N 3.46Å; S336-L339 PolarHBondContact O-N 3.47Å; S336-L340 WeakPolarHBondContact O-CB 3.48Å; S336-L340 PolarHBondContact O-N 3Å
337	S	96.1	Very high	91.3	Very high	0 Å²	0	47.7 Å²	47.7	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-63.5	-37.9	173.6	63.4	0	0	0	0	111.9	L117 Y289 L333 L334 S341	L117-S337 VanDerWaalsContact CD1-OG 3.31Å; L117-S337 WeakPolarHBondContact CD1-OG 3.37Å; Y289-S337 PolarHBondContact OH-OG 3.42Å; L333-S337 PolarHBondContact O-N 2.97Å; L333-S337 PolarHBondContact O-OG 2.98Å; L334-S337 PolarHBondContact O-OG 3.5Å; S337-S341 WeakPolarHBondContact O-CB 3.31Å; S337-S341 PolarHBondContact O-N 3.15Å
338	Y	95.8	Very high	91.1	Very high	32 Å²	32	44.5 Å²	44.5	13%	0.125	25%	0.247	C	C	.	.	H	α-helix	trans	-62.8	-52	174.2	178.8	-103.7	0	0	0	112.6	L117 S139 L143 L334 L335 S336 L340 S341 L342	L117-Y338 HydrophobicContact CD2-CD2 4.43Å; S139-Y338 WeakPolarHBondContact OG-CE2 3.4Å; S139-Y338 PolarHBondContact OG-OH 3.43Å; L143-Y338 HydrophobicContact CB-CD2 3.98Å; L143-Y338 HydrophobicContact CB-CE2 3.99Å; L143-Y338 HydrophobicContact CD1-CD2 4.18Å; L143-Y338 HydrophobicContact CD1-CG 4.29Å; L143-Y338 HydrophobicContact CD2-CD1 4.21Å; L143-Y338 HydrophobicContact CD2-CD2 4.01Å; L143-Y338 HydrophobicContact CD2-CE1 4.32Å; L143-Y338 HydrophobicContact CD2-CE2 4.09Å; L143-Y338 HydrophobicContact CD2-CG 4.07Å; L143-Y338 HydrophobicContact CG-CD2 4.29Å; L334-Y338 VanDerWaalsContact O-CB 3.27Å; L334-Y338 WeakPolarHBondContact O-CB 3.39Å; L334-Y338 PolarHBondContact O-N 3.41Å; L335-Y338 WeakPolarHBondContact O-CB 3.47Å; L335-Y338 PolarHBondContact O-N 3.45Å; S336-Y338 VanDerWaalsContact C-N 3.3Å; S336-Y338 PolarHBondContact O-N 3.46Å; Y338-L340 VanDerWaalsContact C-N 3.29Å; Y338-L340 PolarHBondContact O-N 3.42Å; Y338-S341 WeakPolarHBondContact O-CB 3.45Å; Y338-S341 PolarHBondContact O-N 3.3Å; Y338-S341 PolarHBondContact O-OG 3.46Å; Y338-L342 HydrophobicContact CD1-CD1 4.35Å; Y338-L342 HydrophobicContact CE1-CD1 3.77Å; Y338-L342 HydrophobicContact CE1-CG 4.45Å; Y338-L342 PolarHBondContact O-N 2.95Å
339	L	94.6	Very high	90.9	Very high	91 Å²	91	38.4 Å²	38.4	48%	0.476	22%	0.217	S	C	.	.	H	α-helix	trans	-59.3	-42.3	178	-69.5	174.9	0	0	0	111.2	L335 S336 S341 L342 L343	L335-L339 HydrophobicContact CD1-CD1 4.46Å; L335-L339 HydrophobicContact CD1-CG 4.31Å; L335-L339 HydrophobicContact CG-CD1 4.21Å; L335-L339 HydrophobicContact CG-CG 4.47Å; L335-L339 VanDerWaalsContact O-CG 3.3Å; L335-L339 WeakPolarHBondContact O-CG 3.4Å; L335-L339 PolarHBondContact O-N 3.09Å; S336-L339 PolarHBondContact O-N 3.47Å; L339-S341 VanDerWaalsContact C-N 3.28Å; L339-S341 PolarHBondContact O-N 3.29Å; L339-L342 WeakPolarHBondContact O-CB 3.38Å; L339-L342 PolarHBondContact O-N 3.22Å; L339-L343 WeakPolarHBondContact O-CG 3.5Å; L339-L343 PolarHBondContact O-N 3Å
340	L	92.8	Very high	90.8	Very high	48 Å²	48	37.8 Å²	37.8	25%	0.251	21%	0.213	S	C	.	.	H	α-helix	trans	-63.8	-34.8	177	-167.6	61.5	0	0	0	112.1	M111 T114 S336 Y338 L342 L343 V344	M111-L340 HydrophobicContact CE-CD2 4.1Å; M111-L340 HydrophobicContact SD-CD2 3.61Å; T114-L340 HydrophobicContact CG2-CB 3.83Å; T114-L340 HydrophobicContact CG2-CD2 4.03Å; T114-L340 HydrophobicContact CG2-CG 3.79Å; S336-L340 WeakPolarHBondContact O-CB 3.48Å; S336-L340 PolarHBondContact O-N 3Å; Y338-L340 VanDerWaalsContact C-N 3.29Å; Y338-L340 PolarHBondContact O-N 3.42Å; L340-L342 PolarHBondContact O-N 3.29Å; L340-L343 PolarHBondContact O-N 3.1Å; L340-L343 VanDerWaalsContact O-N 3.11Å; L340-V344 HydrophobicContact CD1-CG2 4.29Å; L340-V344 HydrophobicContact CG-CG2 4.3Å; L340-V344 WeakPolarHBondContact O-CG2 3.41Å; L340-V344 PolarHBondContact O-N 2.69Å
341	S	92.7	Very high	90.7	Very high	6 Å²	6	37.8 Å²	37.8	4%	0.042	21%	0.214	C	C	.	.	H	α-helix	trans	-67.4	-24	178.1	77.2	0	0	0	0	113.2	S337 Y338 L339	S337-S341 WeakPolarHBondContact O-CB 3.31Å; S337-S341 PolarHBondContact O-N 3.15Å; Y338-S341 WeakPolarHBondContact O-CB 3.45Å; Y338-S341 PolarHBondContact O-N 3.3Å; Y338-S341 PolarHBondContact O-OG 3.46Å; L339-S341 VanDerWaalsContact C-N 3.28Å; L339-S341 PolarHBondContact O-N 3.29Å
342	L	90.6	Very high	90.6	Very high	95 Å²	95	36.6 Å²	36.6	50%	0.497	20%	0.201	S	C	.	.	H	α-helix	trans	-78.7	-28.2	173.6	-60.7	177.9	0	0	0	112.4	S139 Y338 L339 L340	S139-L342 WeakPolarHBondContact OG-CD2 3.37Å; Y338-L342 HydrophobicContact CD1-CD1 4.35Å; Y338-L342 HydrophobicContact CE1-CD1 3.77Å; Y338-L342 HydrophobicContact CE1-CG 4.45Å; Y338-L342 PolarHBondContact O-N 2.95Å; L339-L342 WeakPolarHBondContact O-CB 3.38Å; L339-L342 PolarHBondContact O-N 3.22Å; L340-L342 PolarHBondContact O-N 3.29Å
343	L	86.8	Confident	90.4	Very high	127 Å²	127	35.1 Å²	35.1	67%	0.665	19%	0.185	S	C	*	.	H	α-helix	trans	-84.6	-25.5	-176.6	-63.9	175.3	0	0	0	113.2	L339 L340 P345	L339-L343 WeakPolarHBondContact O-CG 3.5Å; L339-L343 PolarHBondContact O-N 3Å; L340-L343 PolarHBondContact O-N 3.1Å; L340-L343 VanDerWaalsContact O-N 3.11Å; L343-P345 WeakPolarHBondContact O-CD 3.45Å
344	V	82	Confident	90.3	Very high	12 Å²	12	35 Å²	35	7%	0.073	18%	0.184	C	C	.	.			trans	-91.4	120.2	-172.9	178.2	0	0	0	0	111.1	L340 L350	L340-V344 HydrophobicContact CD1-CG2 4.29Å; L340-V344 HydrophobicContact CG-CG2 4.3Å; L340-V344 WeakPolarHBondContact O-CG2 3.41Å; L340-V344 PolarHBondContact O-N 2.69Å; V344-L350 HydrophobicContact CB-CD1 4.49Å; V344-L350 HydrophobicContact CB-CD2 4.31Å; V344-L350 HydrophobicContact CG1-CB 3.9Å; V344-L350 HydrophobicContact CG1-CD1 3.91Å; V344-L350 HydrophobicContact CG1-CD2 3.94Å; V344-L350 HydrophobicContact CG1-CG 4.13Å; V344-L350 HydrophobicContact CG2-CD1 3.88Å; V344-L350 HydrophobicContact CG2-CD2 4.24Å
345	P	69.8	Low	90.1	Very high	49 Å²	49	34.8 Å²	34.8	32%	0.318	18%	0.183	S	C	.	.			trans	-83.2	-23.7	-173.1	30.4	-34.4	0	0	0	114.1	L343 A412 I413	L343-P345 WeakPolarHBondContact O-CD 3.45Å; P345-A412 HydrophobicContact CG-CB 4.15Å; P345-I413 HydrophobicContact CG-CG1 4.16Å
346	R	82.4	Confident	90	Very high	74 Å²	74	30.3 Å²	30.3	28%	0.279	16%	0.16	S	C	.	.			trans	-134.1	132.5	-170.9	-61.5	-158.5	-69.2	152.2	-16.9	113.5	E263 L349 L350	E263-R346 IonicContact OE1-NH1 3.81Å; E263-R346 PolarHBondContact OE1-NH1 2.98Å; R346-L349 HydrophobicContact CB-CB 4.21Å; R346-L349 HydrophobicContact CB-CD1 4.18Å; R346-L349 HydrophobicContact CB-CG 4.08Å; R346-L349 VanDerWaalsContact CZ-CG 3.43Å; R346-L350 PolarHBondContact O-N 3.14Å
347	F	86	Confident	89.7	Confident	9 Å²	9	30.9 Å²	30.9	4%	0.039	16%	0.161	C	C	.	.	H	α-helix	trans	-72	-46.1	-177.3	173.1	-111.9	0	0	0	111.6	F20 L115 L118 V119 E263 V264 L349 L350 M351	F20-F347 HydrophobicContact CD1-CE2 4.41Å; F20-F347 HydrophobicContact CD1-CZ 4.27Å; L115-F347 HydrophobicContact CB-CE2 4.32Å; L115-F347 HydrophobicContact CD2-CD2 3.49Å; L115-F347 VanDerWaalsContact CD2-CD2 3.49Å; L115-F347 HydrophobicContact CD2-CE2 3.63Å; L118-F347 HydrophobicContact CD2-CB 4.31Å; V119-F347 HydrophobicContact CG2-CD2 3.27Å; V119-F347 HydrophobicContact CG2-CE1 4.46Å; V119-F347 HydrophobicContact CG2-CE2 3.12Å; V119-F347 HydrophobicContact CG2-CG 4.03Å; V119-F347 HydrophobicContact CG2-CZ 3.75Å; E263-F347 PolarHBondContact OE2-N 3.27Å; E263-F347 VanDerWaalsContact OE2-N 3.1Å; V264-F347 HydrophobicContact CG2-CD1 4.08Å; V264-F347 HydrophobicContact CG2-CG 4.46Å; F347-L349 PolarHBondContact O-N 3.48Å; F347-L350 PolarHBondContact O-N 3.49Å; F347-M351 HydrophobicContact CD1-CE 4.24Å; F347-M351 HydrophobicContact CE1-CE 3.37Å; F347-M351 HydrophobicContact CE2-CE 3.72Å; F347-M351 HydrophobicContact CZ-CE 3.07Å; F347-M351 WeakPolarHBondContact O-CB 3.32Å; F347-M351 PolarHBondContact O-N 2.82Å; F347-M351 VanDerWaalsContact O-N 3.08Å
348	S	86.6	Confident	89.6	Confident	4 Å²	4	31.2 Å²	31.2	3%	0.028	16%	0.163	C	C	.	.	H	α-helix	trans	-62.1	-42.6	-177.6	72.2	0	0	0	0	112	V207 E263 M351 G352	V207-S348 WeakPolarHBondContact CG2-O 3.36Å; E263-S348 VanDerWaalsContact CD-CB 3.46Å; E263-S348 PolarHBondContact OE1-OG 2.99Å; E263-S348 WeakPolarHBondContact OE2-CB 3.42Å; E263-S348 PolarHBondContact OE2-N 3.15Å; E263-S348 PolarHBondContact OE2-OG 3.2Å; S348-M351 PolarHBondContact O-N 3.47Å; S348-G352 PolarHBondContact O-N 3.03Å
349	L	87.7	Confident	89.4	Confident	4 Å²	4	29.7 Å²	29.7	2%	0.021	16%	0.157	C	C	.	.	H	α-helix	trans	-64.8	-43.6	178.6	-73.7	-169.7	0	0	0	112.5	V203 R346 F347 M351 G352 L353 K408 L409 A412	V203-L349 HydrophobicContact CG1-CD2 4.32Å; R346-L349 HydrophobicContact CB-CB 4.21Å; R346-L349 HydrophobicContact CB-CD1 4.18Å; R346-L349 HydrophobicContact CB-CG 4.08Å; R346-L349 VanDerWaalsContact CZ-CG 3.43Å; F347-L349 PolarHBondContact O-N 3.48Å; L349-M351 VanDerWaalsContact C-N 3.27Å; L349-M351 PolarHBondContact O-N 2.96Å; L349-G352 PolarHBondContact O-N 3.14Å; L349-L353 VanDerWaalsContact O-CB 3.31Å; L349-L353 WeakPolarHBondContact O-CB 3.34Å; L349-L353 PolarHBondContact O-N 3.14Å; L349-K408 HydrophobicContact CD1-CB 4.32Å; L349-K408 HydrophobicContact CD2-CB 3.73Å; L349-K408 HydrophobicContact CD2-CD 4.43Å; L349-L409 HydrophobicContact CD1-CB 4.15Å; L349-L409 HydrophobicContact CD1-CD1 4.04Å; L349-A412 HydrophobicContact CD1-CB 4.21Å
350	L	90.9	Very high	89.5	Confident	2 Å²	2	25.3 Å²	25.3	1%	0.01	13%	0.134	C	C	.	.	H	α-helix	trans	-63.9	-40.7	-179.7	-167.8	64	0	0	0	110.5	M111 T114 L115 V344 R346 F347 T354	M111-L350 HydrophobicContact CE-CD1 3.06Å; M111-L350 HydrophobicContact CE-CD2 4.41Å; M111-L350 HydrophobicContact CE-CG 3.9Å; T114-L350 HydrophobicContact CG2-CD2 3.9Å; L115-L350 HydrophobicContact CD2-CB 3.77Å; L115-L350 HydrophobicContact CD2-CD2 3.66Å; L115-L350 HydrophobicContact CD2-CG 3.88Å; L115-L350 HydrophobicContact CG-CD2 3.74Å; L115-L350 HydrophobicContact CG-CG 4.11Å; V344-L350 HydrophobicContact CB-CD1 4.49Å; V344-L350 HydrophobicContact CB-CD2 4.31Å; V344-L350 HydrophobicContact CG1-CB 3.9Å; V344-L350 HydrophobicContact CG1-CD1 3.91Å; V344-L350 HydrophobicContact CG1-CD2 3.94Å; V344-L350 HydrophobicContact CG1-CG 4.13Å; V344-L350 HydrophobicContact CG2-CD1 3.88Å; V344-L350 HydrophobicContact CG2-CD2 4.24Å; R346-L350 PolarHBondContact O-N 3.14Å; F347-L350 PolarHBondContact O-N 3.49Å; L350-T354 WeakPolarHBondContact O-CB 3.19Å; L350-T354 PolarHBondContact O-N 2.63Å; L350-T354 PolarHBondContact O-OG1 2.99Å
351	M	92.7	Very high	89.6	Confident	1 Å²	1	24.2 Å²	24.2	1%	0.005	13%	0.132	C	C	.	.	H	α-helix	trans	-64.5	-47.3	174.5	-166.8	-176.7	-60.2	0	0	111.9	F20 L115 V207 F210 F347 S348 L349 L353 T354 G355	F20-M351 HydrophobicContact CB-CE 3.66Å; F20-M351 HydrophobicContact CB-SD 4.09Å; F20-M351 HydrophobicContact CD1-CE 3.67Å; F20-M351 HydrophobicContact CG-CE 4.04Å; L115-M351 HydrophobicContact CD1-CB 4.49Å; L115-M351 HydrophobicContact CD2-CB 4.37Å; V207-M351 HydrophobicContact CB-CG 4.44Å; V207-M351 HydrophobicContact CB-SD 4.19Å; V207-M351 HydrophobicContact CG1-CG 4.4Å; V207-M351 HydrophobicContact CG1-SD 3.54Å; V207-M351 VanDerWaalsContact CG1-SD 3.54Å; V207-M351 HydrophobicContact CG2-CB 4.11Å; V207-M351 HydrophobicContact CG2-CG 4.22Å; V207-M351 HydrophobicContact CG2-SD 4.31Å; F210-M351 HydrophobicContact CB-CG 3.98Å; F210-M351 HydrophobicContact CD1-CB 4.45Å; F210-M351 HydrophobicContact CD1-CG 3.29Å; F210-M351 HydrophobicContact CD1-SD 4.09Å; F210-M351 HydrophobicContact CE1-CG 4.04Å; F210-M351 HydrophobicContact CG-CG 3.92Å; F347-M351 HydrophobicContact CD1-CE 4.24Å; F347-M351 HydrophobicContact CE1-CE 3.37Å; F347-M351 HydrophobicContact CE2-CE 3.72Å; F347-M351 HydrophobicContact CZ-CE 3.07Å; F347-M351 WeakPolarHBondContact O-CB 3.32Å; F347-M351 PolarHBondContact O-N 2.82Å; F347-M351 VanDerWaalsContact O-N 3.08Å; S348-M351 PolarHBondContact O-N 3.47Å; L349-M351 VanDerWaalsContact C-N 3.27Å; L349-M351 PolarHBondContact O-N 2.96Å; M351-L353 PolarHBondContact O-N 3.12Å; M351-T354 PolarHBondContact O-N 3.28Å; M351-G355 PolarHBondContact O-N 2.92Å
352	G	92.6	Very high	89.6	Confident	0 Å²	0	24 Å²	24	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-60.8	-42.8	177.3	0	0	0	0	0	113.2	S348 L349 S356	S348-G352 PolarHBondContact O-N 3.03Å; L349-G352 PolarHBondContact O-N 3.14Å; G352-S356 VanDerWaalsContact O-CB 3.28Å; G352-S356 WeakPolarHBondContact O-CB 3.41Å; G352-S356 PolarHBondContact O-N 3.31Å; G352-S356 PolarHBondContact O-OG 2.87Å
353	L	92.3	Very high	89.8	Confident	30 Å²	30	19.5 Å²	19.5	16%	0.157	11%	0.107	C	C	.	.	H	α-helix	trans	-63.5	-48.7	175.2	-178.6	67.5	0	0	0	111	L349 M351 G355 S356 V357 V406 L409	L349-L353 VanDerWaalsContact O-CB 3.31Å; L349-L353 WeakPolarHBondContact O-CB 3.34Å; L349-L353 PolarHBondContact O-N 3.14Å; M351-L353 PolarHBondContact O-N 3.12Å; L353-G355 VanDerWaalsContact C-N 3.32Å; L353-G355 PolarHBondContact O-N 3.49Å; L353-S356 PolarHBondContact O-N 3.39Å; L353-V357 HydrophobicContact CD1-CG2 3.7Å; L353-V357 HydrophobicContact CG-CG2 4.2Å; L353-V357 WeakPolarHBondContact O-CB 3.35Å; L353-V357 WeakPolarHBondContact O-CG2 3.44Å; L353-V357 PolarHBondContact O-N 3.3Å; L353-V406 HydrophobicContact CD1-CG2 4.05Å; L353-L409 HydrophobicContact CD2-CD2 4.26Å
354	T	93.4	Very high	90.2	Very high	3 Å²	3	13.9 Å²	13.9	2%	0.018	8%	0.077	C	C	.	.	H	α-helix	trans	-61.4	-43.6	-179.7	-51.8	0	0	0	0	110.7	E108 M111 F210 L350 M351 T358 G359	E108-T354 HydrophobicContact CG-CG2 4.15Å; M111-T354 HydrophobicContact CB-CG2 3.68Å; M111-T354 WeakPolarHBondContact CB-OG1 3.33Å; M111-T354 HydrophobicContact CG-CG2 4.18Å; F210-T354 HydrophobicContact CD2-CG2 3.49Å; F210-T354 VanDerWaalsContact CD2-CG2 3.49Å; F210-T354 HydrophobicContact CE2-CG2 3.25Å; F210-T354 HydrophobicContact CZ-CG2 4.13Å; L350-T354 WeakPolarHBondContact O-CB 3.19Å; L350-T354 PolarHBondContact O-N 2.63Å; L350-T354 PolarHBondContact O-OG1 2.99Å; M351-T354 PolarHBondContact O-N 3.28Å; T354-T358 PolarHBondContact O-N 3.22Å; T354-T358 VanDerWaalsContact O-N 3.11Å; T354-T358 PolarHBondContact O-OG1 3.03Å; T354-T358 VanDerWaalsContact O-OG1 3.04Å; T354-G359 PolarHBondContact O-N 2.99Å
355	G	94.1	Very high	90.9	Very high	0 Å²	0	14.8 Å²	14.8	0%	0	8%	0.081	C	C	.	.	I	π-helix	trans	-67.1	-36.3	176.5	0	0	0	0	0	114.4	G206 M351 L353 G359 A360	G206-G355 WeakPolarHBondContact O-CA 3.46Å; M351-G355 PolarHBondContact O-N 2.92Å; L353-G355 VanDerWaalsContact C-N 3.32Å; L353-G355 PolarHBondContact O-N 3.49Å; G355-G359 CarbonylContact O-C 3.54Å; G355-G359 WeakPolarHBondContact O-CA 3.31Å; G355-A360 PolarHBondContact O-N 2.92Å
356	S	93.3	Very high	92.2	Very high	2 Å²	2	13.6 Å²	13.6	1%	0.014	7%	0.073	C	C	.	.	I	π-helix	trans	-75.1	-38.3	179.4	-58.4	0	0	0	0	112.5	G352 L353 A360 S398 G401	G352-S356 VanDerWaalsContact O-CB 3.28Å; G352-S356 WeakPolarHBondContact O-CB 3.41Å; G352-S356 PolarHBondContact O-N 3.31Å; G352-S356 PolarHBondContact O-OG 2.87Å; L353-S356 PolarHBondContact O-N 3.39Å; S356-A360 WeakPolarHBondContact O-CB 3.47Å; S356-S398 WeakPolarHBondContact O-CA 3.42Å; S356-S398 VanDerWaalsContact O-CB 3.25Å; S356-S398 WeakPolarHBondContact O-CB 3.23Å; S356-S398 PolarHBondContact O-OG 3.49Å; S356-G401 WeakPolarHBondContact OG-CA 3.47Å
357	V	91	Very high	92.9	Very high	59 Å²	59	10.1 Å²	10.1	36%	0.358	6%	0.059	S	C	.	.	I	π-helix	trans	-85.1	-74.7	-176.8	-174.8	0	0	0	0	110.1	L353 A361 V402	L353-V357 HydrophobicContact CD1-CG2 3.7Å; L353-V357 HydrophobicContact CG-CG2 4.2Å; L353-V357 WeakPolarHBondContact O-CB 3.35Å; L353-V357 WeakPolarHBondContact O-CG2 3.44Å; L353-V357 PolarHBondContact O-N 3.3Å; V357-A361 WeakPolarHBondContact O-CB 3.17Å; V357-A361 PolarHBondContact O-N 2.83Å; V357-V402 HydrophobicContact CB-CG2 4.45Å; V357-V402 HydrophobicContact CG2-CG2 3.51Å
358	T	92.8	Very high	93.4	Very high	7 Å²	7	9.7 Å²	9.7	4%	0.043	6%	0.057	C	C	.	.	I	π-helix	trans	-83.3	-40.3	-171.1	58.5	0	0	0	0	111	I107 E108 T354 A360 A361 M362	I107-T358 HydrophobicContact CB-CG2 4.13Å; I107-T358 HydrophobicContact CG2-CG2 3.75Å; E108-T358 HydrophobicContact CB-CG2 4.31Å; E108-T358 VanDerWaalsContact CB-OG1 3.3Å; E108-T358 WeakPolarHBondContact CB-OG1 3.15Å; E108-T358 WeakPolarHBondContact CG-OG1 3.44Å; E108-T358 VanDerWaalsContact OE2-CB 3.3Å; E108-T358 WeakPolarHBondContact OE2-CB 3.4Å; E108-T358 PolarHBondContact OE2-OG1 3.24Å; T354-T358 PolarHBondContact O-N 3.22Å; T354-T358 VanDerWaalsContact O-N 3.11Å; T354-T358 PolarHBondContact O-OG1 3.03Å; T354-T358 VanDerWaalsContact O-OG1 3.04Å; T358-A360 PolarHBondContact O-N 2.97Å; T358-A361 PolarHBondContact O-N 3.31Å; T358-M362 WeakPolarHBondContact O-CB 3.25Å; T358-M362 VanDerWaalsContact O-CG 3.26Å; T358-M362 WeakPolarHBondContact O-CG 3.38Å; T358-M362 PolarHBondContact O-N 2.96Å
359	G	93.1	Very high	93.9	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	8%	0.075	C	C	.	.	I	π-helix	trans	-56.6	-56.3	177.9	0	0	0	0	0	111.5	E108 T354 G355 A361 M362 T363	E108-G359 PolarHBondContact OE2-N 2.95Å; T354-G359 PolarHBondContact O-N 2.99Å; G355-G359 CarbonylContact O-C 3.54Å; G355-G359 WeakPolarHBondContact O-CA 3.31Å; G359-A361 VanDerWaalsContact C-N 3.29Å; G359-A361 PolarHBondContact O-N 3.48Å; G359-M362 PolarHBondContact O-N 3.07Å; G359-T363 WeakPolarHBondContact O-CB 3.34Å; G359-T363 VanDerWaalsContact O-CG2 3.24Å; G359-T363 WeakPolarHBondContact O-CG2 3.29Å; G359-T363 PolarHBondContact O-N 2.68Å; G359-T363 PolarHBondContact O-OG1 3.11Å
360	A	95.4	Very high	94.3	Very high	0 Å²	0	12.9 Å²	12.9	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-59.1	-40.3	178.6	0	0	0	0	0	111.9	G355 S356 T358 L364 I365	G355-A360 PolarHBondContact O-N 2.92Å; S356-A360 WeakPolarHBondContact O-CB 3.47Å; T358-A360 PolarHBondContact O-N 2.97Å; A360-L364 HydrophobicContact CB-CD1 4.41Å; A360-L364 WeakPolarHBondContact O-CA 3.41Å; A360-L364 VanDerWaalsContact O-CB 3.29Å; A360-L364 WeakPolarHBondContact O-CB 3.38Å; A360-L364 PolarHBondContact O-N 3.37Å; A360-I365 WeakPolarHBondContact O-CG1 3.45Å; A360-I365 PolarHBondContact O-N 3.49Å
361	A	94.8	Very high	94.5	Very high	25 Å²	25	13.1 Å²	13.1	21%	0.207	8%	0.075	C	C	.	.	I	π-helix	trans	-62.3	-53.5	176.8	0	0	0	0	0	112.4	V357 T358 G359 I365 L366	V357-A361 WeakPolarHBondContact O-CB 3.17Å; V357-A361 PolarHBondContact O-N 2.83Å; T358-A361 PolarHBondContact O-N 3.31Å; G359-A361 VanDerWaalsContact C-N 3.29Å; G359-A361 PolarHBondContact O-N 3.48Å; A361-I365 PolarHBondContact O-N 3.14Å; A361-L366 WeakPolarHBondContact O-CB 3.47Å; A361-L366 VanDerWaalsContact O-CG 3.31Å; A361-L366 WeakPolarHBondContact O-CG 3.46Å; A361-L366 PolarHBondContact O-N 3.18Å
362	M	94	Very high	94.6	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	8%	0.078	C	C	.	.	I	π-helix	trans	-79.8	-24.2	-171.8	-61.8	-59.7	-65	0	0	113.3	Y78 I101 A104 Q105 I216 T358 G359 L366 P367	Y78-M362 HydrophobicContact CD1-CE 4.02Å; Y78-M362 HydrophobicContact CD2-CE 3.89Å; Y78-M362 HydrophobicContact CE1-CE 3.81Å; Y78-M362 HydrophobicContact CE2-CE 3.69Å; Y78-M362 HydrophobicContact CG-CE 4.06Å; Y78-M362 PolarHBondContact OH-O 3.33Å; I101-M362 HydrophobicContact CG2-CE 4.24Å; A104-M362 HydrophobicContact CB-SD 3.86Å; Q105-M362 HydrophobicContact CG-CE 3.31Å; Q105-M362 HydrophobicContact CG-SD 4.48Å; I216-M362 HydrophobicContact CG1-CE 4.2Å; T358-M362 WeakPolarHBondContact O-CB 3.25Å; T358-M362 VanDerWaalsContact O-CG 3.26Å; T358-M362 WeakPolarHBondContact O-CG 3.38Å; T358-M362 PolarHBondContact O-N 2.96Å; G359-M362 PolarHBondContact O-N 3.07Å; M362-L366 HydrophobicContact SD-CD1 3.57Å; M362-L366 VanDerWaalsContact SD-CD1 3.57Å; M362-P367 WeakPolarHBondContact O-CD 3.47Å; M362-P367 VanDerWaalsContact O-CG 3.31Å; M362-P367 WeakPolarHBondContact O-CG 3.47Å
363	T	94	Very high	94.6	Very high	1 Å²	1	18.3 Å²	18.3	1%	0.006	10%	0.098	C	C	.	.	I	π-helix	trans	-106.4	-29.5	-173.8	70.8	0	0	0	0	114.2	T49 T213 Q215 G359	T49-T363 WeakPolarHBondContact CB-O 3.17Å; T49-T363 WeakPolarHBondContact CG2-O 3.4Å; T49-T363 PolarHBondContact OG1-O 3.19Å; T213-T363 HydrophobicContact CG2-CG2 3.57Å; Q215-T363 HydrophobicContact CB-CG2 4.33Å; Q215-T363 VanDerWaalsContact CD-CB 3.46Å; Q215-T363 HydrophobicContact CG-CG2 4.18Å; G359-T363 WeakPolarHBondContact O-CB 3.34Å; G359-T363 VanDerWaalsContact O-CG2 3.24Å; G359-T363 WeakPolarHBondContact O-CG2 3.29Å; G359-T363 PolarHBondContact O-N 2.68Å; G359-T363 PolarHBondContact O-OG1 3.11Å
364	L	96.3	Very high	94.6	Very high	9 Å²	9	19.3 Å²	19.3	5%	0.047	10%	0.103	C	C	.	.	I	π-helix	trans	-112.1	-56.2	-176.6	-49.4	-178.8	0	0	0	111.2	V45 I209 A360 C368 I390	V45-L364 HydrophobicContact CG1-CD2 3.42Å; V45-L364 VanDerWaalsContact CG1-CD2 3.42Å; I209-L364 HydrophobicContact CD1-CD1 3.92Å; I209-L364 HydrophobicContact CG1-CD1 4.41Å; A360-L364 HydrophobicContact CB-CD1 4.41Å; A360-L364 WeakPolarHBondContact O-CA 3.41Å; A360-L364 VanDerWaalsContact O-CB 3.29Å; A360-L364 WeakPolarHBondContact O-CB 3.38Å; A360-L364 PolarHBondContact O-N 3.37Å; L364-C368 WeakPolarHBondContact O-CB 3.31Å; L364-C368 PolarHBondContact O-SG 3Å; L364-I390 HydrophobicContact CB-CG2 4.11Å; L364-I390 HydrophobicContact CD2-CG2 4.24Å
365	I	97.1	Very high	94.5	Very high	31 Å²	31	20.7 Å²	20.7	16%	0.159	11%	0.108	C	C	.	.	I	π-helix	trans	-72.2	-60.3	-169.1	-61.3	174.5	0	0	0	111.2	A360 A361 C368 L369 L391 V395	A360-I365 WeakPolarHBondContact O-CG1 3.45Å; A360-I365 PolarHBondContact O-N 3.49Å; A361-I365 PolarHBondContact O-N 3.14Å; I365-C368 PolarHBondContact O-N 3.36Å; I365-L369 WeakPolarHBondContact O-CB 3.35Å; I365-L369 PolarHBondContact O-N 3.31Å; I365-L391 HydrophobicContact CB-CD1 4.11Å; I365-L391 HydrophobicContact CG1-CD1 4.48Å; I365-L391 HydrophobicContact CG2-CD1 3.61Å; I365-V395 HydrophobicContact CD1-CG2 4Å; I365-V395 HydrophobicContact CG1-CG2 4.28Å
366	L	96.3	Very high	94.2	Very high	25 Å²	25	27 Å²	27	13%	0.131	13%	0.132	C	C	.	.	H	α-helix	trans	-65.5	-44.6	-171.4	-70	174.3	0	0	0	113.5	Y78 I101 A361 M362 C368 L369 F370	Y78-L366 HydrophobicContact CE1-CB 4.01Å; Y78-L366 HydrophobicContact CE1-CD1 3.96Å; Y78-L366 WeakPolarHBondContact OH-CB 3.43Å; I101-L366 HydrophobicContact CD1-CD1 4.24Å; I101-L366 HydrophobicContact CG1-CD1 4.18Å; A361-L366 WeakPolarHBondContact O-CB 3.47Å; A361-L366 VanDerWaalsContact O-CG 3.31Å; A361-L366 WeakPolarHBondContact O-CG 3.46Å; A361-L366 PolarHBondContact O-N 3.18Å; M362-L366 HydrophobicContact SD-CD1 3.57Å; M362-L366 VanDerWaalsContact SD-CD1 3.57Å; L366-C368 VanDerWaalsContact C-N 3.34Å; L366-C368 PolarHBondContact O-N 3.28Å; L366-L369 HydrophobicContact CD2-CD2 4.48Å; L366-L369 PolarHBondContact O-N 3.36Å; L366-F370 HydrophobicContact CB-CE1 4.46Å; L366-F370 HydrophobicContact CB-CE2 4.09Å; L366-F370 HydrophobicContact CB-CZ 3.97Å; L366-F370 HydrophobicContact CD2-CE1 4Å; L366-F370 HydrophobicContact CD2-CZ 3.93Å; L366-F370 HydrophobicContact CG-CZ 4.38Å; L366-F370 WeakPolarHBondContact O-CB 3.36Å; L366-F370 WeakPolarHBondContact O-CD1 3.45Å; L366-F370 WeakPolarHBondContact O-CD2 3.5Å; L366-F370 WeakPolarHBondContact O-CG 3.27Å; L366-F370 PolarHBondContact O-N 2.97Å
367	P	96.8	Very high	93.9	Very high	0 Å²	0	30.3 Å²	30.3	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-59.5	-43.4	178.1	-25.9	36.8	0	0	0	112.9	T49 L53 Y78 M362 F370 H371	T49-P367 HydrophobicContact CG2-CB 4.5Å; L53-P367 HydrophobicContact CB-CB 4.24Å; Y78-P367 WeakPolarHBondContact OH-CD 3.3Å; Y78-P367 WeakPolarHBondContact OH-CG 3.48Å; M362-P367 WeakPolarHBondContact O-CD 3.47Å; M362-P367 VanDerWaalsContact O-CG 3.31Å; M362-P367 WeakPolarHBondContact O-CG 3.47Å; P367-F370 PolarHBondContact O-N 3.43Å; P367-H371 VanDerWaalsContact O-CB 3.29Å; P367-H371 WeakPolarHBondContact O-CB 3.48Å; P367-H371 PolarHBondContact O-N 3.46Å
368	C	97.2	Very high	93.7	Very high	0 Å²	0	34.9 Å²	34.9	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-67.4	-43.3	177.5	-71	0	0	0	0	111.4	L364 I365 L366 F370 H371 L372 D387 L391	L364-C368 WeakPolarHBondContact O-CB 3.31Å; L364-C368 PolarHBondContact O-SG 3Å; I365-C368 PolarHBondContact O-N 3.36Å; L366-C368 VanDerWaalsContact C-N 3.34Å; L366-C368 PolarHBondContact O-N 3.28Å; C368-F370 VanDerWaalsContact C-N 3.34Å; C368-F370 PolarHBondContact O-N 2.66Å; C368-H371 PolarHBondContact O-N 3.38Å; C368-L372 VanDerWaalsContact O-CB 3.32Å; C368-L372 WeakPolarHBondContact O-CB 3.23Å; C368-L372 WeakPolarHBondContact O-CG 3.37Å; C368-L372 PolarHBondContact O-N 3.07Å; C368-D387 HydrophobicContact CB-CB 4.1Å; C368-L391 HydrophobicContact CB-CB 4.21Å
369	L	96.1	Very high	93.5	Very high	76 Å²	76	35.2 Å²	35.2	40%	0.398	18%	0.178	S	C	.	.	H	α-helix	trans	-57.1	-47.8	175.4	-171	91.8	0	0	0	111.3	I365 L366 K373	I365-L369 WeakPolarHBondContact O-CB 3.35Å; I365-L369 PolarHBondContact O-N 3.31Å; L366-L369 HydrophobicContact CD2-CD2 4.48Å; L366-L369 PolarHBondContact O-N 3.36Å; L369-K373 VanDerWaalsContact O-CB 3.25Å; L369-K373 WeakPolarHBondContact O-CB 3.22Å; L369-K373 PolarHBondContact O-N 3.47Å
370	F	95.5	Very high	93.5	Very high	0 Å²	0	37.9 Å²	37.9	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-65.3	-44.7	-179.3	-62.1	-18.5	0	0	0	112.1	L53 Y78 I81 M82 C85 I101 L366 P367 C368 K373 L374	L53-F370 HydrophobicContact CD1-CD2 4.15Å; Y78-F370 AromaticContact CD1-CE2 3.76Å; Y78-F370 HydrophobicContact CD1-CE2 3.76Å; Y78-F370 HydrophobicContact CD1-CZ 4.38Å; Y78-F370 HydrophobicContact CE1-CD2 4.29Å; Y78-F370 AromaticContact CE1-CE2 3.32Å; Y78-F370 HydrophobicContact CE1-CE2 3.32Å; Y78-F370 AromaticContact CE1-CZ 3.96Å; Y78-F370 HydrophobicContact CE1-CZ 3.96Å; I81-F370 HydrophobicContact CB-CD2 4.06Å; I81-F370 HydrophobicContact CB-CE2 4.18Å; I81-F370 HydrophobicContact CG2-CB 3.72Å; I81-F370 HydrophobicContact CG2-CD1 4.36Å; I81-F370 HydrophobicContact CG2-CD2 3.31Å; I81-F370 HydrophobicContact CG2-CE2 3.89Å; I81-F370 HydrophobicContact CG2-CG 3.57Å; M82-F370 HydrophobicContact CB-CE1 4.34Å; M82-F370 HydrophobicContact CB-CZ 3.99Å; M82-F370 HydrophobicContact SD-CE1 3.66Å; M82-F370 HydrophobicContact SD-CZ 4.01Å; C85-F370 HydrophobicContact CB-CD1 4.22Å; C85-F370 WeakPolarHBondContact SG-CD1 3.24Å; I101-F370 HydrophobicContact CD1-CE2 4.36Å; I101-F370 HydrophobicContact CD1-CZ 3.64Å; L366-F370 HydrophobicContact CB-CE1 4.46Å; L366-F370 HydrophobicContact CB-CE2 4.09Å; L366-F370 HydrophobicContact CB-CZ 3.97Å; L366-F370 HydrophobicContact CD2-CE1 4Å; L366-F370 HydrophobicContact CD2-CZ 3.93Å; L366-F370 HydrophobicContact CG-CZ 4.38Å; L366-F370 WeakPolarHBondContact O-CB 3.36Å; L366-F370 WeakPolarHBondContact O-CD1 3.45Å; L366-F370 WeakPolarHBondContact O-CD2 3.5Å; L366-F370 WeakPolarHBondContact O-CG 3.27Å; L366-F370 PolarHBondContact O-N 2.97Å; P367-F370 PolarHBondContact O-N 3.43Å; C368-F370 VanDerWaalsContact C-N 3.34Å; C368-F370 PolarHBondContact O-N 2.66Å; F370-K373 PolarHBondContact O-N 2.87Å; F370-L374 VanDerWaalsContact O-CB 3.29Å; F370-L374 WeakPolarHBondContact O-CB 3.48Å; F370-L374 WeakPolarHBondContact O-CG 3.45Å; F370-L374 PolarHBondContact O-N 2.88Å
371	H	95.4	Very high	93.5	Very high	7 Å²	7	42.6 Å²	42.6	3%	0.032	23%	0.229	C	C	.	.	H	α-helix	trans	-63.5	-46.9	179.6	-174.2	-109	0	0	0	111.1	K52 P367 C368 K373 R375 L379 D387	K52-H371 HydrophobicContact CB-CB 4.06Å; K52-H371 WeakPolarHBondContact CD-NE2 3.28Å; K52-H371 WeakPolarHBondContact CE-CE1 3.3Å; K52-H371 PolarHBondContact NZ-CE1 3.03Å; K52-H371 VanDerWaalsContact NZ-CE1 3.3Å; K52-H371 PolarHBondContact NZ-NE2 3.34Å; P367-H371 VanDerWaalsContact O-CB 3.29Å; P367-H371 WeakPolarHBondContact O-CB 3.48Å; P367-H371 PolarHBondContact O-N 3.46Å; C368-H371 PolarHBondContact O-N 3.38Å; H371-K373 PolarHBondContact O-N 3.49Å; H371-R375 VanDerWaalsContact O-CB 3.26Å; H371-R375 WeakPolarHBondContact O-CB 3.37Å; H371-R375 PolarHBondContact O-N 3.18Å; H371-L379 WeakPolarHBondContact CE1-CD2 3.49Å; H371-D387 IonicContact CE1-OD2 3.9Å; H371-D387 PolarHBondContact CE1-OD2 3.39Å; H371-D387 IonicContact CG-OD2 3.99Å; H371-D387 IonicContact ND1-OD2 2.59Å; H371-D387 PolarHBondContact ND1-OD2 2.78Å
372	L	95.3	Very high	93.4	Very high	11 Å²	11	48.3 Å²	48.3	6%	0.058	25%	0.251	C	S	.	.	H	α-helix	trans	-58.8	-47	174.3	-71.5	170.3	0	0	0	111.5	C368 W376 L379 R384 D387 M388 L391	C368-L372 VanDerWaalsContact O-CB 3.32Å; C368-L372 WeakPolarHBondContact O-CB 3.23Å; C368-L372 WeakPolarHBondContact O-CG 3.37Å; C368-L372 PolarHBondContact O-N 3.07Å; L372-W376 HydrophobicContact CB-CE3 4.37Å; L372-W376 HydrophobicContact CD2-CE3 4.16Å; L372-W376 HydrophobicContact CD2-CZ3 3.97Å; L372-W376 VanDerWaalsContact O-CA 3.25Å; L372-W376 WeakPolarHBondContact O-CA 3.13Å; L372-W376 WeakPolarHBondContact O-CB 3.24Å; L372-W376 PolarHBondContact O-N 2.84Å; L372-L379 HydrophobicContact CD2-CD1 4.08Å; L372-R384 HydrophobicContact CD2-CB 4.28Å; L372-R384 HydrophobicContact CD2-CG 4.32Å; L372-D387 HydrophobicContact CD1-CB 3.96Å; L372-D387 HydrophobicContact CD2-CB 3.89Å; L372-D387 HydrophobicContact CG-CB 3.8Å; L372-M388 HydrophobicContact CD1-CG 4.02Å; L372-M388 HydrophobicContact CD1-SD 3.56Å; L372-M388 VanDerWaalsContact CD1-SD 3.56Å; L372-L391 HydrophobicContact CD1-CD2 4.42Å
373	K	93.4	Very high	93.4	Very high	99 Å²	99	51.4 Å²	51.4	43%	0.43	27%	0.266	S	S	.	.	H	α-helix	trans	-72.2	-40.8	-174.6	-158.7	-93.6	178	180	0	113.2	C85 L369 F370 H371	C85-K373 HydrophobicContact CB-CD 4.18Å; C85-K373 WeakPolarHBondContact O-CE 3.45Å; C85-K373 PolarHBondContact O-NZ 2.98Å; L369-K373 VanDerWaalsContact O-CB 3.25Å; L369-K373 WeakPolarHBondContact O-CB 3.22Å; L369-K373 PolarHBondContact O-N 3.47Å; F370-K373 PolarHBondContact O-N 2.87Å; H371-K373 PolarHBondContact O-N 3.49Å
374	L	92	Very high	93.4	Very high	51 Å²	51	54.4 Å²	54.4	27%	0.267	28%	0.277	S	S	.	.	H	α-helix	trans	-83.2	-28.6	-177	-65.7	174.3	0	0	0	113	C56 I81 A84 C85 F370	C56-L374 HydrophobicContact CB-CD1 3.97Å; I81-L374 HydrophobicContact CG2-CD1 3.84Å; A84-L374 HydrophobicContact CB-CD2 4.3Å; C85-L374 VanDerWaalsContact SG-CG 3.58Å; F370-L374 VanDerWaalsContact O-CB 3.29Å; F370-L374 WeakPolarHBondContact O-CB 3.48Å; F370-L374 WeakPolarHBondContact O-CG 3.45Å; F370-L374 PolarHBondContact O-N 2.88Å
375	R	90.8	Very high	93.4	Very high	31 Å²	31	59.1 Å²	59.1	12%	0.117	30%	0.302	C	S	.	.	H	α-helix	trans	-113.7	0.1	-173.7	-57.8	-73.4	-168.5	-167.2	-0.8	114.1	A55 Y58 H371 G377 R378 L379	A55-R375 PolarHBondContact O-NH2 3.29Å; Y58-R375 PolarHBondContact O-NH2 3.38Å; H371-R375 VanDerWaalsContact O-CB 3.26Å; H371-R375 WeakPolarHBondContact O-CB 3.37Å; H371-R375 PolarHBondContact O-N 3.18Å; R375-G377 PolarHBondContact O-N 2.88Å; R375-R378 PolarHBondContact O-N 3.35Å; R375-L379 HydrophobicContact CB-CD1 4.24Å; R375-L379 HydrophobicContact CB-CD2 3.7Å; R375-L379 HydrophobicContact CB-CG 3.86Å; R375-L379 WeakPolarHBondContact O-CG 3.35Å; R375-L379 PolarHBondContact O-N 2.84Å
376	W	88.9	Confident	93.4	Very high	134 Å²	134	59.8 Å²	59.8	51%	0.508	31%	0.305	S	S	.	.	G	3₁₀ helix	trans	-33.9	-60.2	-170.7	-172.1	-101.3	0	0	0	114.8	L372 R378 L379 R384	L372-W376 HydrophobicContact CB-CE3 4.37Å; L372-W376 HydrophobicContact CD2-CE3 4.16Å; L372-W376 HydrophobicContact CD2-CZ3 3.97Å; L372-W376 VanDerWaalsContact O-CA 3.25Å; L372-W376 WeakPolarHBondContact O-CA 3.13Å; L372-W376 WeakPolarHBondContact O-CB 3.24Å; L372-W376 PolarHBondContact O-N 2.84Å; W376-R378 PolarHBondContact O-N 2.98Å; W376-R378 VanDerWaalsContact O-N 3.09Å; W376-L379 PolarHBondContact O-N 3.4Å; W376-R384 PolarHBondContact O-NE 2.93Å; W376-R384 PolarHBondContact O-NH2 2.66Å
377	G	86.9	Confident	93.4	Very high	70 Å²	70	58.6 Å²	58.6	72%	0.722	30%	0.299	S	S	*	.	G	3₁₀ helix	trans	-64.7	-13.8	-174.8	0	0	0	0	0	115.5	R375	R375-G377 PolarHBondContact O-N 2.88Å
378	R	85.5	Confident	93.4	Very high	155 Å²	155	63 Å²	63	59%	0.585	32%	0.321	S	S	*	.	G	3₁₀ helix	trans	-107.1	-13.3	-178.8	-57	-177.2	-171.8	173.1	5.7	113.3	E60 R375 W376	E60-R378 IonicContact OE2-CZ 3.55Å; E60-R378 IonicContact OE2-NH1 2.71Å; E60-R378 PolarHBondContact OE2-NH1 3Å; R375-R378 PolarHBondContact O-N 3.35Å; W376-R378 PolarHBondContact O-N 2.98Å; W376-R378 VanDerWaalsContact O-N 3.09Å
379	L	89.3	Confident	93.4	Very high	14 Å²	14	66.5 Å²	66.5	7%	0.073	35%	0.345	C	S	.	.	S	Bend	trans	-75.2	136.9	-177.7	-62	-178	0	0	0	111.7	H371 L372 R375 W376 R384	H371-L379 WeakPolarHBondContact CE1-CD2 3.49Å; L372-L379 HydrophobicContact CD2-CD1 4.08Å; R375-L379 HydrophobicContact CB-CD1 4.24Å; R375-L379 HydrophobicContact CB-CD2 3.7Å; R375-L379 HydrophobicContact CB-CG 3.86Å; R375-L379 WeakPolarHBondContact O-CG 3.35Å; R375-L379 PolarHBondContact O-N 2.84Å; W376-L379 PolarHBondContact O-N 3.4Å; L379-R384 HydrophobicContact CB-CG 3.7Å; L379-R384 HydrophobicContact CD1-CG 4.22Å; L379-R384 PolarHBondContact O-NE 3.36Å; L379-R384 PolarHBondContact O-NH2 2.9Å
380	A	92.9	Very high	93.5	Very high	56 Å²	56	63.4 Å²	63.4	46%	0.463	33%	0.328	S	S	.	.			trans	-64.5	151.9	166.7	0	0	0	0	0	110.2	Q382 E383 R384	A380-Q382 PolarHBondContact O-N 2.81Å; A380-E383 HydrophobicContact CB-CG 4.37Å; A380-E383 PolarHBondContact O-N 3.3Å; A380-E383 VanDerWaalsContact O-N 3.08Å; A380-R384 PolarHBondContact O-N 2.8Å; A380-R384 VanDerWaalsContact O-N 3.08Å
381	V	94.2	Very high	93.6	Very high	99 Å²	99	64.7 Å²	64.7	60%	0.6	34%	0.335	S	S	*	.	H	α-helix	trans	-57.1	-39.4	-179.9	179.3	0	0	0	0	111.3	E383 R384 L385	V381-E383 PolarHBondContact O-N 2.92Å; V381-R384 PolarHBondContact O-N 3.19Å; V381-L385 HydrophobicContact CG1-CD1 4.14Å; V381-L385 HydrophobicContact CG1-CG 4.38Å; V381-L385 WeakPolarHBondContact O-CG 3.09Å; V381-L385 PolarHBondContact O-N 2.72Å
382	Q	93.8	Very high	93.6	Very high	146 Å²	146	67.6 Å²	67.6	68%	0.682	36%	0.357	S	S	*	.	H	α-helix	trans	-60.1	-44.5	176.8	-175	179.9	-4.7	0	0	112.3	A380 R384 L385 I386	A380-Q382 PolarHBondContact O-N 2.81Å; Q382-R384 VanDerWaalsContact C-N 3.34Å; Q382-R384 PolarHBondContact O-N 3.17Å; Q382-L385 PolarHBondContact O-N 3.27Å; Q382-I386 HydrophobicContact CG-CD1 4.04Å; Q382-I386 WeakPolarHBondContact O-CG1 3.21Å; Q382-I386 PolarHBondContact O-N 2.95Å
383	E	92.9	Very high	93.6	Very high	64 Å²	64	70.9 Å²	70.9	30%	0.299	37%	0.374	S	S	.	.	H	α-helix	trans	-64.8	-40.4	177.8	-64.5	-172.1	118	0	0	111.4	K52 A380 V381 L385 I386 D387	K52-E383 IonicContact NZ-OE1 3.82Å; K52-E383 PolarHBondContact NZ-OE1 3.41Å; A380-E383 HydrophobicContact CB-CG 4.37Å; A380-E383 PolarHBondContact O-N 3.3Å; A380-E383 VanDerWaalsContact O-N 3.08Å; V381-E383 PolarHBondContact O-N 2.92Å; E383-L385 VanDerWaalsContact C-N 3.34Å; E383-L385 PolarHBondContact O-N 2.92Å; E383-I386 PolarHBondContact O-N 3.2Å; E383-D387 WeakPolarHBondContact O-CB 3.29Å; E383-D387 PolarHBondContact O-N 3.27Å
384	R	94.9	Very high	93.7	Very high	64 Å²	64	66.2 Å²	66.2	24%	0.242	35%	0.353	C	S	.	.	H	α-helix	trans	-60.4	-44.1	175.2	-64	-178.1	-171.2	163.4	4.3	111.6	L372 W376 L379 A380 V381 Q382 D387 M388	L372-R384 HydrophobicContact CD2-CB 4.28Å; L372-R384 HydrophobicContact CD2-CG 4.32Å; W376-R384 PolarHBondContact O-NE 2.93Å; W376-R384 PolarHBondContact O-NH2 2.66Å; L379-R384 HydrophobicContact CB-CG 3.7Å; L379-R384 HydrophobicContact CD1-CG 4.22Å; L379-R384 PolarHBondContact O-NE 3.36Å; L379-R384 PolarHBondContact O-NH2 2.9Å; A380-R384 PolarHBondContact O-N 2.8Å; A380-R384 VanDerWaalsContact O-N 3.08Å; V381-R384 PolarHBondContact O-N 3.19Å; Q382-R384 VanDerWaalsContact C-N 3.34Å; Q382-R384 PolarHBondContact O-N 3.17Å; R384-D387 PolarHBondContact O-N 2.98Å; R384-M388 VanDerWaalsContact O-CB 3.31Å; R384-M388 WeakPolarHBondContact O-CB 3.46Å; R384-M388 WeakPolarHBondContact O-CG 3.46Å; R384-M388 PolarHBondContact O-N 3.43Å
385	L	96.2	Very high	93.9	Very high	109 Å²	109	67 Å²	67	57%	0.571	36%	0.36	S	S	*	.	H	α-helix	trans	-65	-42.4	178.8	-71.5	174.1	0	0	0	111.9	V381 Q382 E383 S389	V381-L385 HydrophobicContact CG1-CD1 4.14Å; V381-L385 HydrophobicContact CG1-CG 4.38Å; V381-L385 WeakPolarHBondContact O-CG 3.09Å; V381-L385 PolarHBondContact O-N 2.72Å; Q382-L385 PolarHBondContact O-N 3.27Å; E383-L385 VanDerWaalsContact C-N 3.34Å; E383-L385 PolarHBondContact O-N 2.92Å; L385-S389 WeakPolarHBondContact O-CB 3.31Å; L385-S389 PolarHBondContact O-N 3.17Å; L385-S389 PolarHBondContact O-OG 3.13Å
386	I	96.7	Very high	94.1	Very high	45 Å²	45	70 Å²	70	23%	0.231	38%	0.382	C	S	.	.	H	α-helix	trans	-61.5	-50.1	176.6	-69.9	167.8	0	0	0	110.3	W44 Q382 E383 M388 S389 I390	W44-I386 HydrophobicContact CH2-CG2 3.92Å; W44-I386 HydrophobicContact CZ3-CG2 4.49Å; Q382-I386 HydrophobicContact CG-CD1 4.04Å; Q382-I386 WeakPolarHBondContact O-CG1 3.21Å; Q382-I386 PolarHBondContact O-N 2.95Å; E383-I386 PolarHBondContact O-N 3.2Å; I386-M388 PolarHBondContact O-N 3.36Å; I386-S389 WeakPolarHBondContact O-CB 3.28Å; I386-S389 PolarHBondContact O-N 3.34Å; I386-I390 HydrophobicContact CG2-CD1 3.74Å; I386-I390 WeakPolarHBondContact O-CG1 3.26Å; I386-I390 PolarHBondContact O-N 3.35Å
387	D	96.6	Very high	94.3	Very high	0 Å²	0	64.2 Å²	64.2	0%	0	36%	0.362	C	S	.	.	H	α-helix	trans	-65.8	-39.5	-178.2	-68.5	-18.1	0	0	0	112	H48 C368 H371 L372 E383 R384 S389 I390 L391	H48-D387 IonicContact CD2-OD1 2.62Å; H48-D387 IonicContact CE1-OD1 3.14Å; H48-D387 IonicContact NE2-OD1 2.59Å; H48-D387 PolarHBondContact NE2-OD1 2.85Å; C368-D387 HydrophobicContact CB-CB 4.1Å; H371-D387 IonicContact CE1-OD2 3.9Å; H371-D387 PolarHBondContact CE1-OD2 3.39Å; H371-D387 IonicContact CG-OD2 3.99Å; H371-D387 IonicContact ND1-OD2 2.59Å; H371-D387 PolarHBondContact ND1-OD2 2.78Å; L372-D387 HydrophobicContact CD1-CB 3.96Å; L372-D387 HydrophobicContact CD2-CB 3.89Å; L372-D387 HydrophobicContact CG-CB 3.8Å; E383-D387 WeakPolarHBondContact O-CB 3.29Å; E383-D387 PolarHBondContact O-N 3.27Å; R384-D387 PolarHBondContact O-N 2.98Å; D387-S389 VanDerWaalsContact C-N 3.32Å; D387-S389 PolarHBondContact O-N 2.93Å; D387-I390 PolarHBondContact O-N 3.1Å; D387-L391 WeakPolarHBondContact O-CB 3.42Å; D387-L391 PolarHBondContact O-N 3.07Å
388	M	96.9	Very high	94.6	Very high	93 Å²	93	61.9 Å²	61.9	46%	0.458	33%	0.334	S	S	.	.	H	α-helix	trans	-64.1	-37.4	173.9	-74.7	-63.1	-62.1	0	0	112.1	L372 R384 I386 L391 S392	L372-M388 HydrophobicContact CD1-CG 4.02Å; L372-M388 HydrophobicContact CD1-SD 3.56Å; L372-M388 VanDerWaalsContact CD1-SD 3.56Å; R384-M388 VanDerWaalsContact O-CB 3.31Å; R384-M388 WeakPolarHBondContact O-CB 3.46Å; R384-M388 WeakPolarHBondContact O-CG 3.46Å; R384-M388 PolarHBondContact O-N 3.43Å; I386-M388 PolarHBondContact O-N 3.36Å; M388-L391 HydrophobicContact SD-CD2 4.22Å; M388-S392 WeakPolarHBondContact O-CB 3.17Å; M388-S392 PolarHBondContact O-N 3.36Å; M388-S392 PolarHBondContact O-OG 3.1Å
389	S	97.1	Very high	95	Very high	72 Å²	72	59 Å²	59	50%	0.503	33%	0.334	S	S	.	.	H	α-helix	trans	-66	-49	177.1	-58.1	0	0	0	0	110.9	L385 I386 D387 L391 S392 L393	L385-S389 WeakPolarHBondContact O-CB 3.31Å; L385-S389 PolarHBondContact O-N 3.17Å; L385-S389 PolarHBondContact O-OG 3.13Å; I386-S389 WeakPolarHBondContact O-CB 3.28Å; I386-S389 PolarHBondContact O-N 3.34Å; D387-S389 VanDerWaalsContact C-N 3.32Å; D387-S389 PolarHBondContact O-N 2.93Å; S389-L391 VanDerWaalsContact C-N 3.34Å; S389-L391 PolarHBondContact O-N 3.36Å; S389-S392 PolarHBondContact O-N 3.45Å; S389-S392 PolarHBondContact O-OG 3.06Å; S389-L393 WeakPolarHBondContact O-CB 3.48Å; S389-L393 PolarHBondContact O-N 2.96Å
390	I	97.6	Very high	95.2	Very high	11 Å²	11	59.9 Å²	59.9	6%	0.056	34%	0.343	C	S	.	.	H	α-helix	trans	-61.9	-42.8	177.4	-65.4	165.8	0	0	0	110.9	W44 V45 T49 L364 I386 D387 S392 L393 G394	W44-I390 HydrophobicContact CZ3-CD1 4.39Å; V45-I390 HydrophobicContact CG1-CD1 4.14Å; V45-I390 HydrophobicContact CG1-CG1 4.19Å; V45-I390 HydrophobicContact CG1-CG2 3.77Å; V45-I390 HydrophobicContact CG2-CG1 4.46Å; T49-I390 HydrophobicContact CG2-CD1 4.45Å; T49-I390 HydrophobicContact CG2-CG2 4.01Å; L364-I390 HydrophobicContact CB-CG2 4.11Å; L364-I390 HydrophobicContact CD2-CG2 4.24Å; I386-I390 HydrophobicContact CG2-CD1 3.74Å; I386-I390 WeakPolarHBondContact O-CG1 3.26Å; I386-I390 PolarHBondContact O-N 3.35Å; D387-I390 PolarHBondContact O-N 3.1Å; I390-S392 PolarHBondContact O-N 2.9Å; I390-L393 PolarHBondContact O-N 2.95Å; I390-G394 PolarHBondContact O-N 3.42Å
391	L	97.5	Very high	95.1	Very high	27 Å²	27	57.2 Å²	57.2	14%	0.141	32%	0.321	C	S	.	.	H	α-helix	trans	-57.9	-49.2	175.7	177	64.7	0	0	0	111.3	I365 C368 L372 D387 M388 S389 G394 V395	I365-L391 HydrophobicContact CB-CD1 4.11Å; I365-L391 HydrophobicContact CG1-CD1 4.48Å; I365-L391 HydrophobicContact CG2-CD1 3.61Å; C368-L391 HydrophobicContact CB-CB 4.21Å; L372-L391 HydrophobicContact CD1-CD2 4.42Å; D387-L391 WeakPolarHBondContact O-CB 3.42Å; D387-L391 PolarHBondContact O-N 3.07Å; M388-L391 HydrophobicContact SD-CD2 4.22Å; S389-L391 VanDerWaalsContact C-N 3.34Å; S389-L391 PolarHBondContact O-N 3.36Å; L391-G394 PolarHBondContact O-N 2.96Å; L391-V395 WeakPolarHBondContact O-CG2 3.06Å; L391-V395 PolarHBondContact O-N 3Å
392	S	96.7	Very high	94.9	Very high	69 Å²	69	55 Å²	55	48%	0.483	31%	0.307	S	S	.	.	H	α-helix	trans	-62.9	-42.9	179.5	70.9	0	0	0	0	112.3	M388 S389 I390 G394 V395 V396	M388-S392 WeakPolarHBondContact O-CB 3.17Å; M388-S392 PolarHBondContact O-N 3.36Å; M388-S392 PolarHBondContact O-OG 3.1Å; S389-S392 PolarHBondContact O-N 3.45Å; S389-S392 PolarHBondContact O-OG 3.06Å; I390-S392 PolarHBondContact O-N 2.9Å; S392-G394 PolarHBondContact O-N 3.43Å; S392-V395 PolarHBondContact O-N 3.29Å; S392-V396 WeakPolarHBondContact O-CG2 3.31Å; S392-V396 PolarHBondContact O-N 3.29Å
393	L	95	Very high	94.8	Very high	80 Å²	80	52.7 Å²	52.7	42%	0.419	30%	0.303	S	S	.	.	H	α-helix	trans	-61.7	-44.7	175.7	179.8	63.6	0	0	0	111	S389 I390 V395 V396 C397	S389-L393 WeakPolarHBondContact O-CB 3.48Å; S389-L393 PolarHBondContact O-N 2.96Å; I390-L393 PolarHBondContact O-N 2.95Å; L393-V395 VanDerWaalsContact C-N 3.34Å; L393-V395 PolarHBondContact O-N 3.49Å; L393-V396 PolarHBondContact O-N 3.07Å; L393-C397 WeakPolarHBondContact O-CB 3.46Å; L393-C397 PolarHBondContact O-N 3.35Å; L393-C397 PolarHBondContact O-SG 3.2Å
394	G	95.9	Very high	94.7	Very high	0 Å²	0	50.5 Å²	50.5	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-59.1	-42.6	177.3	0	0	0	0	0	112.8	I390 L391 S392 S398	I390-G394 PolarHBondContact O-N 3.42Å; L391-G394 PolarHBondContact O-N 2.96Å; S392-G394 PolarHBondContact O-N 3.43Å; G394-S398 VanDerWaalsContact O-CB 3.24Å; G394-S398 WeakPolarHBondContact O-CB 3.33Å; G394-S398 PolarHBondContact O-N 3.35Å
395	V	96.4	Very high	94.3	Very high	69 Å²	69	47.4 Å²	47.4	42%	0.418	28%	0.283	S	S	.	.	H	α-helix	trans	-63.9	-46.1	176.3	172.8	0	0	0	0	111.2	I365 L391 S392 L393 S398 V399	I365-V395 HydrophobicContact CD1-CG2 4Å; I365-V395 HydrophobicContact CG1-CG2 4.28Å; L391-V395 WeakPolarHBondContact O-CG2 3.06Å; L391-V395 PolarHBondContact O-N 3Å; S392-V395 PolarHBondContact O-N 3.29Å; L393-V395 VanDerWaalsContact C-N 3.34Å; L393-V395 PolarHBondContact O-N 3.49Å; V395-S398 PolarHBondContact O-N 2.79Å; V395-V399 HydrophobicContact CG1-CG2 4.4Å; V395-V399 WeakPolarHBondContact O-CG2 3.13Å; V395-V399 PolarHBondContact O-N 2.66Å
396	V	94.6	Very high	93.9	Very high	93 Å²	93	45.4 Å²	45.4	56%	0.564	28%	0.275	S	S	*	.	H	α-helix	trans	-61.6	-49.8	178.4	172.3	0	0	0	0	111	S392 L393 S398 V399 A400	S392-V396 WeakPolarHBondContact O-CG2 3.31Å; S392-V396 PolarHBondContact O-N 3.29Å; L393-V396 PolarHBondContact O-N 3.07Å; V396-S398 VanDerWaalsContact C-N 3.27Å; V396-S398 PolarHBondContact O-N 2.95Å; V396-V399 PolarHBondContact O-N 2.98Å; V396-A400 VanDerWaalsContact O-CB 3.28Å; V396-A400 WeakPolarHBondContact O-CB 3.46Å; V396-A400 PolarHBondContact O-N 3.14Å
397	C	92.5	Very high	93.6	Very high	13 Å²	13	48.6 Å²	48.6	9%	0.088	29%	0.287	C	S	.	.	H	α-helix	trans	-59.6	-39.1	177.6	-69	0	0	0	0	111.8	I209 L393 G401	I209-C397 HydrophobicContact CD1-CB 4.16Å; L393-C397 WeakPolarHBondContact O-CB 3.46Å; L393-C397 PolarHBondContact O-N 3.35Å; L393-C397 PolarHBondContact O-SG 3.2Å; C397-G401 VanDerWaalsContact O-CA 3.29Å; C397-G401 WeakPolarHBondContact O-CA 3.48Å; C397-G401 PolarHBondContact O-N 3.2Å
398	S	94.2	Very high	93.1	Very high	21 Å²	21	50 Å²	50	15%	0.147	29%	0.293	C	S	.	.	H	α-helix	trans	-69.4	-50.4	-179.4	-167.2	0	0	0	0	112.3	S356 G394 V395 V396 G401 V402	S356-S398 WeakPolarHBondContact O-CA 3.42Å; S356-S398 VanDerWaalsContact O-CB 3.25Å; S356-S398 WeakPolarHBondContact O-CB 3.23Å; S356-S398 PolarHBondContact O-OG 3.49Å; G394-S398 VanDerWaalsContact O-CB 3.24Å; G394-S398 WeakPolarHBondContact O-CB 3.33Å; G394-S398 PolarHBondContact O-N 3.35Å; V395-S398 PolarHBondContact O-N 2.79Å; V396-S398 VanDerWaalsContact C-N 3.27Å; V396-S398 PolarHBondContact O-N 2.95Å; S398-G401 PolarHBondContact O-N 3.21Å; S398-V402 WeakPolarHBondContact O-CB 3.17Å; S398-V402 WeakPolarHBondContact O-CG2 3.43Å; S398-V402 PolarHBondContact O-N 2.89Å
399	V	94.1	Very high	92.6	Very high	95 Å²	95	47 Å²	47	58%	0.576	28%	0.279	S	S	*	.	H	α-helix	trans	-63.1	-49.9	-179.9	174.6	0	0	0	0	111	V395 V396 V403	V395-V399 HydrophobicContact CG1-CG2 4.4Å; V395-V399 WeakPolarHBondContact O-CG2 3.13Å; V395-V399 PolarHBondContact O-N 2.66Å; V396-V399 PolarHBondContact O-N 2.98Å; V399-V403 WeakPolarHBondContact O-CG2 3.18Å; V399-V403 PolarHBondContact O-N 2.91Å
400	A	93.4	Very high	92.1	Very high	31 Å²	31	47.9 Å²	47.9	26%	0.256	28%	0.281	S	S	.	.	H	α-helix	trans	-65.1	-42.2	179.4	0	0	0	0	0	111.6	I202 V396 V403 C404	I202-A400 HydrophobicContact CD1-CB 4.1Å; I202-A400 HydrophobicContact CG1-CB 4.37Å; I202-A400 HydrophobicContact CG2-CB 3.97Å; V396-A400 VanDerWaalsContact O-CB 3.28Å; V396-A400 WeakPolarHBondContact O-CB 3.46Å; V396-A400 PolarHBondContact O-N 3.14Å; A400-V403 PolarHBondContact O-N 3.4Å; A400-C404 PolarHBondContact O-N 3.22Å; A400-C404 PolarHBondContact O-SG 3.29Å
401	G	90.9	Very high	91.6	Very high	0 Å²	0	52.1 Å²	52.1	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-67	-38.6	-177.4	0	0	0	0	0	114	I202 S356 C397 S398 S405	I202-G401 VanDerWaalsContact CG2-CA 3.42Å; S356-G401 WeakPolarHBondContact OG-CA 3.47Å; C397-G401 VanDerWaalsContact O-CA 3.29Å; C397-G401 WeakPolarHBondContact O-CA 3.48Å; C397-G401 PolarHBondContact O-N 3.2Å; S398-G401 PolarHBondContact O-N 3.21Å; G401-S405 WeakPolarHBondContact O-CB 3.38Å; G401-S405 PolarHBondContact O-N 3.08Å; G401-S405 PolarHBondContact O-OG 3Å
402	V	89.8	Confident	91	Very high	53 Å²	53	51.4 Å²	51.4	32%	0.321	30%	0.301	S	S	.	.	H	α-helix	trans	-60.3	-50.9	172.8	171	0	0	0	0	110.3	V357 S398 C404 V406	V357-V402 HydrophobicContact CB-CG2 4.45Å; V357-V402 HydrophobicContact CG2-CG2 3.51Å; S398-V402 WeakPolarHBondContact O-CB 3.17Å; S398-V402 WeakPolarHBondContact O-CG2 3.43Å; S398-V402 PolarHBondContact O-N 2.89Å; V402-C404 PolarHBondContact O-N 2.94Å; V402-V406 HydrophobicContact CG1-CG2 4.27Å; V402-V406 VanDerWaalsContact O-CB 3.29Å; V402-V406 WeakPolarHBondContact O-CB 3.36Å; V402-V406 WeakPolarHBondContact O-CG2 3.43Å; V402-V406 PolarHBondContact O-N 3.37Å
403	V	91.3	Very high	90.3	Very high	97 Å²	97	51.5 Å²	51.5	59%	0.588	30%	0.296	S	S	*	.	H	α-helix	trans	-60.5	-48.4	-177.4	174.9	0	0	0	0	110.9	V399 A400 K407	V399-V403 WeakPolarHBondContact O-CG2 3.18Å; V399-V403 PolarHBondContact O-N 2.91Å; A400-V403 PolarHBondContact O-N 3.4Å; V403-K407 VanDerWaalsContact O-CB 3.28Å; V403-K407 WeakPolarHBondContact O-CB 3.38Å; V403-K407 PolarHBondContact O-N 3.39Å; V403-K407 VanDerWaalsContact O-N 3.17Å
404	C	90.4	Very high	89.7	Confident	18 Å²	18	50.2 Å²	50.2	12%	0.122	29%	0.293	C	S	.	.	H	α-helix	trans	-68.8	-45	-178	-61.2	0	0	0	0	112.3	E199 I202 V203 A400 V402 K408	E199-C404 HydrophobicContact CB-CB 4.46Å; I202-C404 HydrophobicContact CG2-CB 4.16Å; V203-C404 HydrophobicContact CG2-CB 4.23Å; A400-C404 PolarHBondContact O-N 3.22Å; A400-C404 PolarHBondContact O-SG 3.29Å; V402-C404 PolarHBondContact O-N 2.94Å; C404-K408 PolarHBondContact O-N 3.46Å; C404-K408 VanDerWaalsContact O-N 3.09Å
405	S	86.9	Confident	89.1	Confident	0 Å²	0	54.5 Å²	54.5	0%	0	32%	0.316	C	S	.	.	H	α-helix	trans	-68.1	-42.4	-177.1	-56.4	0	0	0	0	111.9	G401 K408 L409	G401-S405 WeakPolarHBondContact O-CB 3.38Å; G401-S405 PolarHBondContact O-N 3.08Å; G401-S405 PolarHBondContact O-OG 3Å; S405-K408 PolarHBondContact O-N 3.33Å; S405-L409 VanDerWaalsContact O-CB 3.25Å; S405-L409 WeakPolarHBondContact O-CB 2.96Å; S405-L409 PolarHBondContact O-N 3Å
406	V	87.3	Confident	87.8	Confident	66 Å²	66	54.2 Å²	54.2	40%	0.4	32%	0.317	S	S	.	.	H	α-helix	trans	-65.6	-45.2	178.2	172.6	0	0	0	0	110.7	L353 V402 K408 L409 V410	L353-V406 HydrophobicContact CD1-CG2 4.05Å; V402-V406 HydrophobicContact CG1-CG2 4.27Å; V402-V406 VanDerWaalsContact O-CB 3.29Å; V402-V406 WeakPolarHBondContact O-CB 3.36Å; V402-V406 WeakPolarHBondContact O-CG2 3.43Å; V402-V406 PolarHBondContact O-N 3.37Å; V406-K408 VanDerWaalsContact C-N 3.33Å; V406-K408 PolarHBondContact O-N 3.1Å; V406-L409 PolarHBondContact O-N 2.95Å; V406-V410 HydrophobicContact CG1-CG2 4.22Å; V406-V410 WeakPolarHBondContact O-CG2 3.38Å; V406-V410 PolarHBondContact O-N 3.48Å
407	K	90.4	Very high	86.3	Confident	113 Å²	113	54.7 Å²	54.7	49%	0.491	32%	0.32	S	S	.	.	H	α-helix	trans	-54.5	-49.2	175.7	-180	-172.5	171.5	-164.3	0	111.4	E199 V403 L411	E199-K407 VanDerWaalsContact CD-NZ 3.29Å; E199-K407 IonicContact OE1-NZ 3.47Å; E199-K407 PolarHBondContact OE1-NZ 3.09Å; E199-K407 IonicContact OE2-NZ 3.71Å; E199-K407 PolarHBondContact OE2-NZ 3.12Å; E199-K407 VanDerWaalsContact OE2-NZ 3.14Å; V403-K407 VanDerWaalsContact O-CB 3.28Å; V403-K407 WeakPolarHBondContact O-CB 3.38Å; V403-K407 PolarHBondContact O-N 3.39Å; V403-K407 VanDerWaalsContact O-N 3.17Å; K407-L411 WeakPolarHBondContact O-CB 3.37Å; K407-L411 PolarHBondContact O-N 3Å; K407-L411 VanDerWaalsContact O-N 3.12Å
408	K	87.1	Confident	84.3	Confident	28 Å²	28	61.5 Å²	61.5	12%	0.122	35%	0.351	C	S	.	.	H	α-helix	trans	-70.3	-30.9	-179.7	-73.7	-177	175.1	176.3	0	113.4	D197 D200 V203 L349 C404 S405 V406 A412	D197-K408 IonicContact OD1-NZ 3.21Å; D200-K408 IonicContact OD1-NZ 3.56Å; D200-K408 PolarHBondContact OD1-NZ 3.08Å; D200-K408 IonicContact OD2-NZ 2.65Å; V203-K408 HydrophobicContact CG2-CD 4.24Å; L349-K408 HydrophobicContact CD1-CB 4.32Å; L349-K408 HydrophobicContact CD2-CB 3.73Å; L349-K408 HydrophobicContact CD2-CD 4.43Å; C404-K408 PolarHBondContact O-N 3.46Å; C404-K408 VanDerWaalsContact O-N 3.09Å; S405-K408 PolarHBondContact O-N 3.33Å; V406-K408 VanDerWaalsContact C-N 3.33Å; V406-K408 PolarHBondContact O-N 3.1Å; K408-A412 VanDerWaalsContact O-CB 3.31Å; K408-A412 WeakPolarHBondContact O-CB 3.24Å; K408-A412 PolarHBondContact O-N 3.45Å
409	L	84.7	Confident	81.7	Confident	30 Å²	30	71.9 Å²	71.9	16%	0.157	39%	0.394	C	S	.	.	H	α-helix	trans	-71.2	-46.4	176.3	-175.8	64.6	0	0	0	111.5	L349 L353 S405 V406 L411 A412 I413	L349-L409 HydrophobicContact CD1-CB 4.15Å; L349-L409 HydrophobicContact CD1-CD1 4.04Å; L353-L409 HydrophobicContact CD2-CD2 4.26Å; S405-L409 VanDerWaalsContact O-CB 3.25Å; S405-L409 WeakPolarHBondContact O-CB 2.96Å; S405-L409 PolarHBondContact O-N 3Å; V406-L409 PolarHBondContact O-N 2.95Å; L409-L411 VanDerWaalsContact C-N 3.31Å; L409-L411 PolarHBondContact O-N 3.49Å; L409-A412 PolarHBondContact O-N 3.3Å; L409-I413 HydrophobicContact CD1-CD1 4.23Å; L409-I413 HydrophobicContact CD1-CG1 4.49Å; L409-I413 HydrophobicContact CG-CD1 3.97Å; L409-I413 WeakPolarHBondContact O-CG1 3.22Å; L409-I413 PolarHBondContact O-N 3.4Å
410	V	87.2	Confident	81.1	Confident	92 Å²	92	70.7 Å²	70.7	56%	0.558	38%	0.384	S	S	*	.	H	α-helix	trans	-59.8	-45	176.5	171.8	0	0	0	0	110.5	V406 A412 I413 S414	V406-V410 HydrophobicContact CG1-CG2 4.22Å; V406-V410 WeakPolarHBondContact O-CG2 3.38Å; V406-V410 PolarHBondContact O-N 3.48Å; V410-A412 PolarHBondContact O-N 3.27Å; V410-I413 PolarHBondContact O-N 2.86Å; V410-S414 PolarHBondContact O-N 3.4Å; V410-S414 PolarHBondContact O-OG 3.43Å
411	L	87.4	Confident	80.5	Confident	99 Å²	99	72.8 Å²	72.8	52%	0.518	39%	0.391	S	S	.	.	H	α-helix	trans	-60.9	-44.9	176.1	-174.4	139	0	0	0	111.8	K407 L409 I413 S414 L415	K407-L411 WeakPolarHBondContact O-CB 3.37Å; K407-L411 PolarHBondContact O-N 3Å; K407-L411 VanDerWaalsContact O-N 3.12Å; L409-L411 VanDerWaalsContact C-N 3.31Å; L409-L411 PolarHBondContact O-N 3.49Å; L411-I413 PolarHBondContact O-N 3.36Å; L411-S414 WeakPolarHBondContact CA-OG 3.47Å; L411-S414 PolarHBondContact O-N 3.32Å; L411-S414 PolarHBondContact O-OG 3.1Å; L411-L415 HydrophobicContact CD2-CD1 3.68Å; L411-L415 HydrophobicContact CG-CD1 4.37Å; L411-L415 WeakPolarHBondContact O-CG 3.32Å; L411-L415 PolarHBondContact O-N 3.35Å; L411-L415 VanDerWaalsContact O-N 3.13Å
412	A	84.3	Confident	79.9	Confident	12 Å²	12	76.8 Å²	76.8	10%	0.099	41%	0.413	C	S	.	.	H	α-helix	trans	-62.8	-40.5	177.7	0	0	0	0	0	112.9	P345 L349 K408 L409 V410 S416	P345-A412 HydrophobicContact CG-CB 4.15Å; L349-A412 HydrophobicContact CD1-CB 4.21Å; K408-A412 VanDerWaalsContact O-CB 3.31Å; K408-A412 WeakPolarHBondContact O-CB 3.24Å; K408-A412 PolarHBondContact O-N 3.45Å; L409-A412 PolarHBondContact O-N 3.3Å; V410-A412 PolarHBondContact O-N 3.27Å; A412-S416 PolarHBondContact O-N 3.08Å; A412-S416 VanDerWaalsContact O-N 3.14Å; A412-S416 PolarHBondContact O-OG 2.05Å
413	I	82.4	Confident	79.3	Confident	71 Å²	71	78.2 Å²	78.2	36%	0.364	42%	0.418	S	S	.	.	H	α-helix	trans	-65.9	-45.4	177.2	-67.7	167.3	0	0	0	110.2	P345 L409 V410 L411 L415 S416 T417	P345-I413 HydrophobicContact CG-CG1 4.16Å; L409-I413 HydrophobicContact CD1-CD1 4.23Å; L409-I413 HydrophobicContact CD1-CG1 4.49Å; L409-I413 HydrophobicContact CG-CD1 3.97Å; L409-I413 WeakPolarHBondContact O-CG1 3.22Å; L409-I413 PolarHBondContact O-N 3.4Å; V410-I413 PolarHBondContact O-N 2.86Å; L411-I413 PolarHBondContact O-N 3.36Å; I413-L415 VanDerWaalsContact C-N 3.3Å; I413-L415 PolarHBondContact O-N 3.13Å; I413-S416 WeakPolarHBondContact CA-OG 3.43Å; I413-S416 PolarHBondContact O-N 2.86Å; I413-S416 PolarHBondContact O-OG 3.05Å; I413-T417 PolarHBondContact O-N 3.23Å; I413-T417 VanDerWaalsContact O-N 3.14Å; I413-T417 PolarHBondContact O-OG1 3.19Å
414	S	83.1	Confident	78.6	Confident	53 Å²	53	77.1 Å²	77.1	37%	0.371	41%	0.408	S	S	.	.	H	α-helix	trans	-58.8	-41.1	179.6	62.2	0	0	0	0	112.8	V410 L411 S416 T417	V410-S414 PolarHBondContact O-N 3.4Å; V410-S414 PolarHBondContact O-OG 3.43Å; L411-S414 WeakPolarHBondContact CA-OG 3.47Å; L411-S414 PolarHBondContact O-N 3.32Å; L411-S414 PolarHBondContact O-OG 3.1Å; S414-S416 VanDerWaalsContact C-N 3.34Å; S414-S416 PolarHBondContact O-N 2.97Å; S414-T417 PolarHBondContact O-N 3.37Å; S414-T417 PolarHBondContact O-OG1 2.94Å
415	L	82.4	Confident	77.8	Confident	90 Å²	90	81 Å²	81	47%	0.471	43%	0.427	S	S	.	.	H	α-helix	trans	-68.7	-33.5	176.6	-68.2	170.3	0	0	0	112.4	L411 I413 T417 E418	L411-L415 HydrophobicContact CD2-CD1 3.68Å; L411-L415 HydrophobicContact CG-CD1 4.37Å; L411-L415 WeakPolarHBondContact O-CG 3.32Å; L411-L415 PolarHBondContact O-N 3.35Å; L411-L415 VanDerWaalsContact O-N 3.13Å; I413-L415 VanDerWaalsContact C-N 3.3Å; I413-L415 PolarHBondContact O-N 3.13Å; L415-T417 VanDerWaalsContact C-N 3.3Å; L415-T417 PolarHBondContact O-N 3.08Å; L415-E418 PolarHBondContact O-N 3.36Å
416	S	70.3	Confident	77.1	Confident	63 Å²	63	86.8 Å²	86.8	44%	0.441	46%	0.457	S	S	.	.	H	α-helix	trans	-73.2	-20.1	178	67.6	0	0	0	0	114.2	A412 I413 S414	A412-S416 PolarHBondContact O-N 3.08Å; A412-S416 VanDerWaalsContact O-N 3.14Å; A412-S416 PolarHBondContact O-OG 2.05Å; I413-S416 WeakPolarHBondContact CA-OG 3.43Å; I413-S416 PolarHBondContact O-N 2.86Å; I413-S416 PolarHBondContact O-OG 3.05Å; S414-S416 VanDerWaalsContact C-N 3.34Å; S414-S416 PolarHBondContact O-N 2.97Å
417	T	62.3	Low	76.4	Confident	104 Å²	104	88.4 Å²	88.4	64%	0.638	46%	0.462	S	S	*	.	H	α-helix	trans	-88.7	-12.2	177	47.4	0	0	0	0	113.8	I413 S414 L415	I413-T417 PolarHBondContact O-N 3.23Å; I413-T417 VanDerWaalsContact O-N 3.14Å; I413-T417 PolarHBondContact O-OG1 3.19Å; S414-T417 PolarHBondContact O-N 3.37Å; S414-T417 PolarHBondContact O-OG1 2.94Å; L415-T417 VanDerWaalsContact C-N 3.3Å; L415-T417 PolarHBondContact O-N 3.08Å
418	E	51.6	Low	75.2	Confident	155 Å²	155	86.3 Å²	86.3	72%	0.724	46%	0.459	S	S	*	.			trans	-88	-5.8	177.4	-71.6	-168.7	156.8	0	0	113.7	L415	L415-E418 PolarHBondContact O-N 3.36Å
419	F	39.6	Very low	74.1	Confident	239 Å²	239	91.6 Å²	91.6	100%	1.048	49%	0.49	S	S	*	.			trans	-121	0	174.6	-73.3	-84.1	0	0	0	110.3

Retrieved 419 of 419 residues in 884.5 ms (Link to these results)

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