A0A087YK21_POEFO Loading...

Coagulation factor II thrombin receptor like 2

AlphaFold DB , UniProt , Accession A0A087YK21, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 369 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35.5	Very low	43.5	Very low	208 Å²	208	96.7 Å²	96.7	100%	1.025	51%	0.51	S	S	*	.				0	-51.9	0	-100	-175.5	-80.2	0	0	112.9	N3 L4 L5	M1-N3 PolarHBondContact O-N 2.86Å; M1-L4 WeakPolarHBondContact O-CB 3.44Å; M1-L4 PolarHBondContact O-N 2.74Å; M1-L5 PolarHBondContact O-N 3.26Å
2	A	30.4	Very low	44	Very low	78 Å²	78	96.8 Å²	96.8	65%	0.645	51%	0.51	S	S	*	.	H	α-helix	trans	-56.1	-43.6	-179.2	0	0	0	0	0	114.3	L4 R6	A2-L4 VanDerWaalsContact C-N 3.29Å; A2-L4 PolarHBondContact O-N 3.21Å; A2-R6 VanDerWaalsContact O-CB 3.26Å; A2-R6 WeakPolarHBondContact O-CB 3.09Å; A2-R6 PolarHBondContact O-N 3.43Å
3	N	36	Very low	44.4	Very low	136 Å²	136	97.7 Å²	97.7	73%	0.727	51%	0.512	S	S	*	.	H	α-helix	trans	-69.1	-26.3	177.7	-65.3	-21.6	0	0	0	113.5	M1 G7	M1-N3 PolarHBondContact O-N 2.86Å; N3-G7 PolarHBondContact O-N 3.18Å
4	L	42.2	Very low	44.7	Very low	90 Å²	90	93.6 Å²	93.6	47%	0.471	49%	0.493	S	S	.	.	H	α-helix	trans	-79.7	-42.7	-179.9	-144.1	112	0	0	0	110.8	M1 A2 R6 G7 L8 L253	M1-L4 WeakPolarHBondContact O-CB 3.44Å; M1-L4 PolarHBondContact O-N 2.74Å; A2-L4 VanDerWaalsContact C-N 3.29Å; A2-L4 PolarHBondContact O-N 3.21Å; L4-R6 VanDerWaalsContact C-N 3.31Å; L4-G7 PolarHBondContact O-N 3.38Å; L4-L8 HydrophobicContact CD2-CD1 4.47Å; L4-L8 PolarHBondContact O-N 3.23Å; L4-L253 HydrophobicContact CD1-CD1 4.43Å; L4-L253 HydrophobicContact CD2-CD1 4.1Å; L4-L253 HydrophobicContact CD2-CD2 4.21Å
5	L	42.2	Very low	44.6	Very low	115 Å²	115	90.5 Å²	90.5	60%	0.602	49%	0.485	S	S	*	.	H	α-helix	trans	-63.5	-39.8	172.4	-157.3	84.3	0	0	0	110.5	M1 L8 L9	M1-L5 PolarHBondContact O-N 3.26Å; L5-L8 PolarHBondContact O-N 2.73Å; L5-L9 HydrophobicContact CD2-CD1 4.05Å; L5-L9 HydrophobicContact CG-CD1 3.98Å; L5-L9 WeakPolarHBondContact O-CB 3.45Å; L5-L9 WeakPolarHBondContact O-CD1 3.26Å; L5-L9 WeakPolarHBondContact O-CG 3.28Å; L5-L9 PolarHBondContact O-N 2.85Å
6	R	44.5	Very low	44.5	Very low	177 Å²	177	93.5 Å²	93.5	67%	0.668	50%	0.496	S	S	*	.	H	α-helix	trans	-65.2	-36.8	175.4	-150.9	175.7	-168.2	-168.1	2.4	112	A2 L4 L10	A2-R6 VanDerWaalsContact O-CB 3.26Å; A2-R6 WeakPolarHBondContact O-CB 3.09Å; A2-R6 PolarHBondContact O-N 3.43Å; L4-R6 VanDerWaalsContact C-N 3.31Å; R6-L10 HydrophobicContact CG-CD1 4.45Å; R6-L10 WeakPolarHBondContact O-CB 3.46Å; R6-L10 VanDerWaalsContact O-CD1 3.31Å; R6-L10 WeakPolarHBondContact O-CD1 3.09Å; R6-L10 VanDerWaalsContact O-CG 3.25Å; R6-L10 WeakPolarHBondContact O-CG 3.24Å; R6-L10 PolarHBondContact O-N 3.38Å
7	G	47.1	Very low	44.3	Very low	12 Å²	12	93.4 Å²	93.4	12%	0.124	50%	0.5	C	S	.	.	H	α-helix	trans	-67.3	-43.6	172.9	0	0	0	0	0	113.5	N3 L4 L10 C11	N3-G7 PolarHBondContact O-N 3.18Å; L4-G7 PolarHBondContact O-N 3.38Å; G7-L10 PolarHBondContact O-N 2.9Å; G7-C11 PolarHBondContact O-N 2.73Å
8	L	48.8	Very low	44	Very low	33 Å²	33	91.7 Å²	91.7	17%	0.173	50%	0.496	C	S	.	.	H	α-helix	trans	-65.3	-43	173.6	-88.8	152.3	0	0	0	112.1	L4 L5 C11 L12 F203 A207	L4-L8 HydrophobicContact CD2-CD1 4.47Å; L4-L8 PolarHBondContact O-N 3.23Å; L5-L8 PolarHBondContact O-N 2.73Å; L8-C11 WeakPolarHBondContact O-CB 3.4Å; L8-C11 PolarHBondContact O-N 3.18Å; L8-L12 WeakPolarHBondContact O-CG 3.36Å; L8-L12 PolarHBondContact O-N 3.37Å; L8-F203 HydrophobicContact CD1-CE1 4.35Å; L8-A207 HydrophobicContact CD2-CB 3.86Å
9	L	52.2	Low	44	Very low	86 Å²	86	96.2 Å²	96.2	45%	0.45	51%	0.514	S	S	.	.	H	α-helix	trans	-64.5	-39.1	173	-82.6	156.7	0	0	0	111.2	L5 L12 M13	L5-L9 HydrophobicContact CD2-CD1 4.05Å; L5-L9 HydrophobicContact CG-CD1 3.98Å; L5-L9 WeakPolarHBondContact O-CB 3.45Å; L5-L9 WeakPolarHBondContact O-CD1 3.26Å; L5-L9 WeakPolarHBondContact O-CG 3.28Å; L5-L9 PolarHBondContact O-N 2.85Å; L9-L12 PolarHBondContact O-N 3.06Å; L9-M13 VanDerWaalsContact O-CB 3.25Å; L9-M13 WeakPolarHBondContact O-CB 3.34Å; L9-M13 WeakPolarHBondContact O-CG 3.31Å; L9-M13 PolarHBondContact O-N 2.08Å
10	L	54.2	Low	43.6	Very low	97 Å²	97	97 Å²	97	51%	0.508	52%	0.522	S	S	.	.	H	α-helix	trans	-62.8	-42.3	172.1	-86.6	156.7	0	0	0	111.4	R6 G7 L12 M13 V14	R6-L10 HydrophobicContact CG-CD1 4.45Å; R6-L10 WeakPolarHBondContact O-CB 3.46Å; R6-L10 VanDerWaalsContact O-CD1 3.31Å; R6-L10 WeakPolarHBondContact O-CD1 3.09Å; R6-L10 VanDerWaalsContact O-CG 3.25Å; R6-L10 WeakPolarHBondContact O-CG 3.24Å; R6-L10 PolarHBondContact O-N 3.38Å; G7-L10 PolarHBondContact O-N 2.9Å; L10-L12 VanDerWaalsContact C-N 3.33Å; L10-L12 PolarHBondContact O-N 3.43Å; L10-M13 PolarHBondContact O-N 3.21Å; L10-V14 WeakPolarHBondContact O-CB 3.37Å; L10-V14 WeakPolarHBondContact O-CG2 3.33Å; L10-V14 PolarHBondContact O-N 3.3Å
11	C	44.9	Very low	43.1	Very low	32 Å²	32	100 Å²	100	22%	0.216	54%	0.538	C	S	.	.	H	α-helix	trans	-59.3	-42.8	172.7	-75.7	0	0	0	0	111.9	G7 L8 A15 C246	G7-C11 PolarHBondContact O-N 2.73Å; L8-C11 WeakPolarHBondContact O-CB 3.4Å; L8-C11 PolarHBondContact O-N 3.18Å; C11-A15 VanDerWaalsContact O-CB 3.31Å; C11-A15 WeakPolarHBondContact O-CB 3.4Å; C11-A15 PolarHBondContact O-N 3.18Å; C11-A15 VanDerWaalsContact O-N 3.07Å; C11-C246 HydrophobicContact CB-CB 4.32Å; C11-C246 WeakPolarHBondContact CB-SG 3.34Å; C11-C246 VanDerWaalsContact SG-CA 3.55Å; C11-C246 WeakPolarHBondContact SG-CB 3.26Å; C11-C246 CovalentContact SG-SG 2.06Å; C11-C246 PolarHBondContact SG-SG 2.75Å
12	L	49.8	Very low	43.3	Very low	97 Å²	97	93.3 Å²	93.3	51%	0.508	52%	0.523	S	S	.	.	H	α-helix	trans	-69.8	-42.2	179.3	-70.8	167.4	0	0	0	112.8	L8 L9 L10 Q16	L8-L12 WeakPolarHBondContact O-CG 3.36Å; L8-L12 PolarHBondContact O-N 3.37Å; L9-L12 PolarHBondContact O-N 3.06Å; L10-L12 VanDerWaalsContact C-N 3.33Å; L10-L12 PolarHBondContact O-N 3.43Å; L12-Q16 WeakPolarHBondContact O-CG 3.39Å; L12-Q16 PolarHBondContact O-N 3.49Å
13	M	49.3	Very low	43.4	Very low	109 Å²	109	100.1 Å²	100.1	54%	0.537	54%	0.537	S	S	.	.	H	α-helix	trans	-75.3	-31.5	-178.9	-64.3	-69.6	-91	0	0	111.8	L9 L10 Q16 T17	L9-M13 VanDerWaalsContact O-CB 3.25Å; L9-M13 WeakPolarHBondContact O-CB 3.34Å; L9-M13 WeakPolarHBondContact O-CG 3.31Å; L9-M13 PolarHBondContact O-N 2.08Å; L10-M13 PolarHBondContact O-N 3.21Å; M13-Q16 PolarHBondContact O-N 2.98Å; M13-T17 PolarHBondContact O-N 2.89Å; M13-T17 VanDerWaalsContact O-N 3.13Å; M13-T17 PolarHBondContact O-OG1 3.29Å
14	V	48.1	Very low	43.2	Very low	41 Å²	41	97.4 Å²	97.4	25%	0.248	54%	0.542	C	S	.	.	H	α-helix	trans	-77.4	-32.8	175.5	-176.2	0	0	0	0	112.2	L10 Q16 T17 S18 P242	L10-V14 WeakPolarHBondContact O-CB 3.37Å; L10-V14 WeakPolarHBondContact O-CG2 3.33Å; L10-V14 PolarHBondContact O-N 3.3Å; V14-Q16 PolarHBondContact O-N 3.12Å; V14-T17 WeakPolarHBondContact CA-OG1 3.47Å; V14-T17 PolarHBondContact O-N 2.98Å; V14-T17 PolarHBondContact O-OG1 2.98Å; V14-S18 PolarHBondContact O-N 3.46Å; V14-P242 HydrophobicContact CB-CB 4.12Å; V14-P242 HydrophobicContact CG1-CB 3.16Å; V14-P242 HydrophobicContact CG1-CG 3.23Å; V14-P242 HydrophobicContact CG2-CB 4.48Å
15	A	43.7	Very low	43	Very low	46 Å²	46	105 Å²	105	38%	0.38	56%	0.564	S	S	.	*	H	α-helix	trans	-57.5	-31.6	167.6	0	0	0	0	0	112.6	C11 L214	C11-A15 VanDerWaalsContact O-CB 3.31Å; C11-A15 WeakPolarHBondContact O-CB 3.4Å; C11-A15 PolarHBondContact O-N 3.18Å; C11-A15 VanDerWaalsContact O-N 3.07Å; A15-L214 HydrophobicContact CB-CD1 3.73Å
16	Q	43	Very low	42.6	Very low	139 Å²	139	109.1 Å²	109.1	65%	0.65	58%	0.577	S	S	*	*	H	α-helix	trans	-83.8	-30	178.2	-70.4	-179.7	-34.8	0	0	114	L12 M13 V14	L12-Q16 WeakPolarHBondContact O-CG 3.39Å; L12-Q16 PolarHBondContact O-N 3.49Å; M13-Q16 PolarHBondContact O-N 2.98Å; V14-Q16 PolarHBondContact O-N 3.12Å
17	T	41.3	Very low	42.1	Very low	92 Å²	92	107.9 Å²	107.9	56%	0.564	59%	0.589	S	S	*	*	H	α-helix	trans	-85.6	-18	-176.7	35.3	0	0	0	0	114.1	M13 V14 Q19 V20	M13-T17 PolarHBondContact O-N 2.89Å; M13-T17 VanDerWaalsContact O-N 3.13Å; M13-T17 PolarHBondContact O-OG1 3.29Å; V14-T17 WeakPolarHBondContact CA-OG1 3.47Å; V14-T17 PolarHBondContact O-N 2.98Å; V14-T17 PolarHBondContact O-OG1 2.98Å; T17-Q19 PolarHBondContact O-N 3.13Å; T17-Q19 VanDerWaalsContact O-N 3.1Å; T17-V20 PolarHBondContact O-N 3.32Å
18	S	38.9	Very low	41.7	Very low	63 Å²	63	110 Å²	110	44%	0.441	61%	0.606	S	S	.	*	T	Hydrogen-bonded Turn	trans	-70.5	-2.1	179.3	-158	0	0	0	0	114.9	V14	V14-S18 PolarHBondContact O-N 3.46Å
19	Q	43.8	Very low	41.4	Very low	177 Å²	177	110.7 Å²	110.7	83%	0.827	61%	0.612	S	S	*	*	T	Hydrogen-bonded Turn	trans	-81.6	-15.2	170.5	-83.3	-94.3	-40.9	0	0	113.6	T17	T17-Q19 PolarHBondContact O-N 3.13Å; T17-Q19 VanDerWaalsContact O-N 3.1Å
20	V	35.8	Very low	40.6	Very low	112 Å²	112	106.8 Å²	106.8	68%	0.679	59%	0.592	S	S	*	*	T	Hydrogen-bonded Turn	trans	-119.1	-15	-157.8	178.2	0	0	0	0	117	T17	T17-V20 PolarHBondContact O-N 3.32Å
21	N	33.7	Very low	40.4	Very low	160 Å²	160	103.1 Å²	103.1	86%	0.856	57%	0.572	S	S	*	*			trans	-144.6	116.1	-175.5	-104.8	-24.7	0	0	0	116
22	G	39.3	Very low	40.9	Very low	68 Å²	68	101.8 Å²	101.8	70%	0.701	56%	0.563	S	S	*	*			trans	-110.7	117.4	166.2	0	0	0	0	0	111.3
23	K	32.2	Very low	41	Very low	220 Å²	220	97.4 Å²	97.4	96%	0.957	54%	0.54	S	S	*	.			trans	176.4	132.8	143.3	-104.4	170.8	-178.9	177.3	0	110.5
24	G	32.1	Very low	41.2	Very low	79 Å²	79	96.6 Å²	96.6	81%	0.814	53%	0.533	S	S	*	.			trans	132	99	165.1	0	0	0	0	0	114.3	K26	G24-K26 PolarHBondContact O-N 2.98Å
25	R	38.8	Very low	41.2	Very low	249 Å²	249	94.6 Å²	94.6	94%	0.94	52%	0.521	S	S	*	.			trans	-71.1	112.1	-175.8	-164	179	-162.7	173	3.2	111.7
26	K	32.5	Very low	41.3	Very low	203 Å²	203	96.7 Å²	96.7	88%	0.883	52%	0.522	S	S	*	.			trans	-145.5	129.7	152.1	-72.3	-167.9	179.3	177.2	0	108.7	G24	G24-K26 PolarHBondContact O-N 2.98Å
27	T	34.9	Very low	41.5	Very low	150 Å²	150	92.9 Å²	92.9	92%	0.92	50%	0.503	S	S	*	.			trans	-62.8	132.7	-168.8	36.5	0	0	0	0	113.4
28	A	37.6	Very low	41.6	Very low	57 Å²	57	91.8 Å²	91.8	47%	0.471	49%	0.494	S	S	.	.			trans	-139.6	152	174.7	0	0	0	0	0	112.6
29	P	43.5	Very low	41.6	Very low	47 Å²	47	97.9 Å²	97.9	31%	0.305	51%	0.513	S	S	.	.			trans	-102.2	174.2	-159.8	0.1	24.2	0	0	0	116	L312 F313	P29-L312 WeakPolarHBondContact CB-O 3.22Å; P29-F313 HydrophobicContact CB-CD1 4.3Å; P29-F313 HydrophobicContact CG-CD1 4.06Å; P29-F313 WeakPolarHBondContact CG-O 3.42Å; P29-F313 WeakPolarHBondContact O-CE1 3.19Å
30	P	35.7	Very low	41.2	Very low	5 Å²	5	93.9 Å²	93.9	3%	0.032	50%	0.504	C	S	.	.			trans	-76.7	176.8	-168.7	18.3	-11.1	0	0	0	116.6	S32 K34 L235 L312 F313	P30-S32 WeakPolarHBondContact CB-O 3.33Å; P30-K34 HydrophobicContact CG-CB 4.48Å; P30-K34 HydrophobicContact CG-CG 4.32Å; P30-L235 HydrophobicContact CB-CD1 3.7Å; P30-L235 HydrophobicContact CB-CD2 3.85Å; P30-L235 HydrophobicContact CB-CG 3.5Å; P30-L235 HydrophobicContact CG-CD1 4Å; P30-L235 HydrophobicContact CG-CD2 3.46Å; P30-L235 VanDerWaalsContact CG-CD2 3.46Å; P30-L235 HydrophobicContact CG-CG 3.73Å; P30-L312 HydrophobicContact CB-CD1 4.29Å; P30-L312 HydrophobicContact CB-CD2 4.35Å; P30-L312 HydrophobicContact CB-CG 4.27Å; P30-L312 HydrophobicContact CG-CD1 3.7Å; P30-L312 HydrophobicContact CG-CG 3.94Å; P30-L312 WeakPolarHBondContact O-CD2 3.09Å; P30-L312 VanDerWaalsContact O-CG 3.23Å; P30-L312 WeakPolarHBondContact O-CG 3.05Å; P30-F313 WeakPolarHBondContact O-CE1 3.37Å; P30-F313 WeakPolarHBondContact O-CZ 3.42Å
31	K	50	Low	41.1	Very low	20 Å²	20	95.1 Å²	95.1	9%	0.087	51%	0.507	C	S	.	.	S	Bend	trans	-123.6	-23.9	178.7	-72.7	171.5	-173.4	157.9	0	115.7	L233 H240 F313	K31-L233 HydrophobicContact CB-CD2 4.49Å; K31-H240 PolarHBondContact NZ-ND1 3.02Å; K31-H240 VanDerWaalsContact NZ-ND1 3.15Å; K31-H240 PolarHBondContact NZ-O 3.42Å; K31-F313 HydrophobicContact CG-CZ 3.9Å
32	S	54.7	Low	41.4	Very low	3 Å²	3	94.8 Å²	94.8	2%	0.021	51%	0.505	C	S	.	.	S	Bend	trans	-142.9	-179.7	163.9	47.6	0	0	0	0	106.2	P30 H230 D231	P30-S32 WeakPolarHBondContact CB-O 3.33Å; S32-H230 PolarHBondContact OG-O 3.32Å; S32-D231 WeakPolarHBondContact CB-O 3.28Å
33	F	51.8	Low	41	Very low	5 Å²	5	97.7 Å²	97.7	2%	0.022	51%	0.51	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-38.6	141.3	-166.6	-72.2	-75.5	0	0	0	115.4	G35 P65 A66 Y69 D318 Y321	F33-G35 PolarHBondContact O-N 3.13Å; F33-P65 HydrophobicContact CD1-CB 3.9Å; F33-P65 HydrophobicContact CE1-CB 3.57Å; F33-P65 VanDerWaalsContact CE1-O 3.24Å; F33-P65 WeakPolarHBondContact CE1-O 3.48Å; F33-A66 HydrophobicContact CB-CB 3.32Å; F33-A66 HydrophobicContact CD1-CB 3.75Å; F33-A66 HydrophobicContact CD2-CB 4.1Å; F33-A66 HydrophobicContact CG-CB 3.47Å; F33-A66 VanDerWaalsContact CG-CB 3.47Å; F33-Y69 HydrophobicContact CD2-CD1 4.37Å; F33-Y69 VanDerWaalsContact CE2-CB 3.5Å; F33-Y69 AromaticContact CE2-CD1 3.42Å; F33-Y69 HydrophobicContact CE2-CD1 3.42Å; F33-Y69 VanDerWaalsContact CE2-CD1 3.42Å; F33-Y69 HydrophobicContact CE2-CD2 4.2Å; F33-Y69 HydrophobicContact CE2-CE1 4.18Å; F33-Y69 AromaticContact CE2-CG 3.43Å; F33-Y69 HydrophobicContact CE2-CG 3.43Å; F33-Y69 VanDerWaalsContact CE2-CG 3.43Å; F33-Y69 HydrophobicContact CZ-CD1 4.07Å; F33-Y69 HydrophobicContact CZ-CD2 4.13Å; F33-Y69 AromaticContact CZ-CG 3.57Å; F33-Y69 HydrophobicContact CZ-CG 3.57Å; F33-D318 HydrophobicContact CD1-CB 4.2Å; F33-D318 VanDerWaalsContact CD1-OD2 3.24Å; F33-D318 WeakPolarHBondContact CD1-OD2 3.29Å; F33-Y321 AromaticContact CD2-CD1 3.92Å; F33-Y321 HydrophobicContact CD2-CD1 3.92Å; F33-Y321 HydrophobicContact CD2-CE1 4.04Å; F33-Y321 HydrophobicContact CD2-CG 4.44Å; F33-Y321 HydrophobicContact CE1-CD1 4.49Å; F33-Y321 AromaticContact CE2-CD1 3.12Å; F33-Y321 HydrophobicContact CE2-CD1 3.12Å; F33-Y321 AromaticContact CE2-CE1 3.46Å; F33-Y321 HydrophobicContact CE2-CE1 3.46Å; F33-Y321 VanDerWaalsContact CE2-CE1 3.46Å; F33-Y321 AromaticContact CE2-CG 3.91Å; F33-Y321 HydrophobicContact CE2-CG 3.91Å; F33-Y321 AromaticContact CZ-CD1 3.47Å; F33-Y321 HydrophobicContact CZ-CD1 3.47Å; F33-Y321 VanDerWaalsContact CZ-CD1 3.47Å; F33-Y321 HydrophobicContact CZ-CE1 4.25Å; F33-Y321 HydrophobicContact CZ-CG 4.05Å
34	K	54.2	Low	41.1	Very low	92 Å²	92	96.4 Å²	96.4	40%	0.4	51%	0.509	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-64.6	124.7	-174.2	-157.6	-176.9	-173.3	177.2	0	111.8	P30 F36 L235	P30-K34 HydrophobicContact CG-CB 4.48Å; P30-K34 HydrophobicContact CG-CG 4.32Å; K34-F36 HydrophobicContact CD-CE2 4.37Å; K34-F36 HydrophobicContact CD-CZ 4.11Å; K34-L235 HydrophobicContact CB-CD1 4.01Å; K34-L235 HydrophobicContact CD-CD1 4.38Å; K34-L235 HydrophobicContact CD-CD2 4.19Å; K34-L235 HydrophobicContact CG-CD1 3.21Å; K34-L235 HydrophobicContact CG-CD2 3.79Å; K34-L235 HydrophobicContact CG-CG 4.12Å
35	G	47.3	Very low	41.3	Very low	0 Å²	0	100.4 Å²	100.4	0%	0	51%	0.507	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.3	147.4	174.7	0	0	0	0	0	113.1	F33 P234 L235	F33-G35 PolarHBondContact O-N 3.13Å; G35-P234 WeakPolarHBondContact O-CA 3.37Å; G35-L235 WeakPolarHBondContact O-CD1 3.46Å
36	F	46.8	Very low	40.8	Very low	90 Å²	90	98 Å²	98	40%	0.395	50%	0.503	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-113	143.5	-179.1	-62.9	-84.6	0	0	0	111.1	K34 D59	K34-F36 HydrophobicContact CD-CE2 4.37Å; K34-F36 HydrophobicContact CD-CZ 4.11Å; F36-D59 PolarHBondContact O-N 2.86Å
37	F	46.9	Very low	40.8	Very low	58 Å²	58	96 Å²	96	25%	0.254	50%	0.501	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.3	131.8	172	-84.5	-81.7	0	0	0	110	P56 L58 Y219 P234 E237	F37-P56 HydrophobicContact CE1-CB 3.92Å; F37-L58 HydrophobicContact CD1-CD1 4.29Å; F37-L58 HydrophobicContact CE1-CD1 4.23Å; F37-L58 HydrophobicContact CZ-CD1 4.42Å; F37-Y219 HydrophobicContact CZ-CE1 4.29Å; F37-P234 HydrophobicContact CD2-CB 3.58Å; F37-P234 HydrophobicContact CD2-CG 4.08Å; F37-P234 HydrophobicContact CE2-CB 3.29Å; F37-P234 HydrophobicContact CE2-CG 3.27Å; F37-P234 HydrophobicContact CZ-CB 4.05Å; F37-P234 HydrophobicContact CZ-CG 3.57Å; F37-E237 HydrophobicContact CE2-CG 4.29Å
38	D	42.5	Very low	40.5	Very low	69 Å²	69	96.3 Å²	96.3	37%	0.369	50%	0.497	S	S	.	.			trans	-78.8	126.4	170.8	179.1	27.5	0	0	0	110.5	S40 R222	D38-S40 PolarHBondContact OD1-N 3.01Å; D38-R222 IonicContact OD2-NH1 2.81Å; D38-R222 PolarHBondContact OD2-NH1 3.27Å
39	K	39	Very low	40.3	Very low	192 Å²	192	100.9 Å²	100.9	84%	0.835	51%	0.513	S	S	*	.			trans	-108.8	63.7	169.9	-77	-176.9	179.2	175.1	0	109.4	N41	K39-N41 PolarHBondContact O-N 3.38Å
40	S	36.3	Very low	40	Very low	92 Å²	92	108.4 Å²	108.4	64%	0.643	54%	0.541	S	S	*	.			trans	-74.1	122	168.5	168.1	0	0	0	0	110.1	D38	D38-S40 PolarHBondContact OD1-N 3.01Å
41	N	34.2	Very low	39.9	Very low	139 Å²	139	119.9 Å²	119.9	74%	0.743	58%	0.584	S	S	*	*			trans	-40.1	130.1	-174	-70.9	-31.5	0	0	0	116.7	K39 T43	K39-N41 PolarHBondContact O-N 3.38Å; N41-T43 PolarHBondContact O-N 2.86Å
42	D	38.9	Very low	39	Very low	153 Å²	153	124 Å²	124	82%	0.818	62%	0.616	S	S	*	*	T	Hydrogen-bonded Turn	trans	-60.3	22.2	177.4	-84.2	-41.2	0	0	0	117.1
43	T	32	Very low	38	Very low	129 Å²	129	128.9 Å²	128.9	79%	0.791	65%	0.65	S	S	*	*	T	Hydrogen-bonded Turn	trans	-104.3	0.2	-171.3	8.5	0	0	0	0	116.7	N41	N41-T43 PolarHBondContact O-N 2.86Å
44	M	32.6	Very low	37.5	Very low	193 Å²	193	136.6 Å²	136.6	95%	0.951	69%	0.689	S	S	*	*	S	Bend	trans	-127.8	18.4	177	-119.6	173.1	96.8	0	0	115.2
45	Q	36.8	Very low	36.9	Very low	163 Å²	163	134.8 Å²	134.8	76%	0.762	69%	0.686	S	S	*	*			trans	-108.5	58.6	179.4	-159.8	175.7	21.7	0	0	111.7
46	K	29.5	Very low	37	Very low	199 Å²	199	136.3 Å²	136.3	87%	0.865	70%	0.696	S	S	*	*	S	Bend	trans	-116	6.1	171.6	-127.5	-179.2	-173	179.5	0	114.5
47	L	31.4	Very low	37	Very low	161 Å²	161	135.6 Å²	135.6	84%	0.843	69%	0.693	S	S	*	*	S	Bend	trans	-131.9	26.5	-174.7	-141.8	84.9	0	0	0	115.8
48	D	28.7	Very low	37.2	Very low	156 Å²	156	132.8 Å²	132.8	83%	0.834	68%	0.681	S	S	*	*			trans	-140.8	36.7	170.2	-83.3	-42	0	0	0	112	F50	D48-F50 VanDerWaalsContact C-N 3.3Å; D48-F50 PolarHBondContact O-N 2.89Å
49	L	33.8	Very low	37.3	Very low	153 Å²	153	131.6 Å²	131.6	80%	0.801	68%	0.675	S	S	*	*			trans	-84.4	69.6	178.6	-162.9	122.5	0	0	0	110.2
50	F	36.1	Very low	37.9	Very low	205 Å²	205	122.9 Å²	122.9	90%	0.899	64%	0.638	S	S	*	*	S	Bend	trans	176.3	79.7	152.3	-105.9	-75.6	0	0	0	110.2	D48	D48-F50 VanDerWaalsContact C-N 3.3Å; D48-F50 PolarHBondContact O-N 2.89Å
51	R	34.2	Very low	38.4	Very low	245 Å²	245	125.2 Å²	125.2	93%	0.925	64%	0.638	S	S	*	*	S	Bend	trans	149.7	89.1	149.7	178.5	167.2	-93.6	-164.9	-8.5	111.8
52	S	30.7	Very low	38.8	Very low	108 Å²	108	123.5 Å²	123.5	76%	0.755	64%	0.635	S	S	*	*			trans	175.6	136.1	138.6	-173.6	0	0	0	0	109.5	I54	S52-I54 PolarHBondContact O-N 2.99Å
53	S	35.3	Very low	39.4	Very low	105 Å²	105	125.3 Å²	125.3	73%	0.734	64%	0.638	S	S	*	*			trans	-52	125.3	170.6	-64.6	0	0	0	0	110.3	V55	S53-V55 PolarHBondContact O-N 3.39Å
54	I	40.4	Very low	40.6	Very low	167 Å²	167	120.1 Å²	120.1	86%	0.856	61%	0.607	S	S	*	*			trans	-66.3	96.5	-175.6	-58.5	169.8	0	0	0	109.3	S52	S52-I54 PolarHBondContact O-N 2.99Å
55	V	42.6	Very low	41.8	Very low	53 Å²	53	113.9 Å²	113.9	32%	0.321	58%	0.581	S	S	.	*	P	Polyproline II helix	trans	-91.5	119.8	168.7	-173.1	0	0	0	0	107.6	S53 H220	S53-V55 PolarHBondContact O-N 3.39Å; V55-H220 HydrophobicContact CG1-CB 3.59Å
56	P	47.6	Very low	43	Very low	33 Å²	33	106.2 Å²	106.2	21%	0.214	55%	0.546	C	S	.	.	P	Polyproline II helix	trans	-68.5	141.7	178.4	23.9	-28.5	0	0	0	111.2	F37 K216 H220	F37-P56 HydrophobicContact CE1-CB 3.92Å; P56-K216 HydrophobicContact CG-CD 4.18Å; P56-K216 VanDerWaalsContact CG-CE 3.42Å; P56-H220 PolarHBondContact O-N 3.38Å
57	H	48.2	Very low	44.5	Very low	74 Å²	74	97.7 Å²	97.7	34%	0.343	51%	0.512	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.3	134.4	-171.2	-61.7	-71.9	0	0	0	111.9	H220 R222	H57-H220 AromaticContact ND1-ND1 3.82Å; H57-R222 HydrophobicContact CB-CG 3.89Å; H57-R222 VanDerWaalsContact CB-NE 3.28Å; H57-R222 PolarHBondContact CD2-NH2 2.98Å; H57-R222 PolarHBondContact ND1-NE 2.95Å
58	L	51	Low	46.2	Very low	0 Å²	0	93.1 Å²	93.1	0%	0	50%	0.498	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-113.7	138.3	171.9	-109.4	75.8	0	0	0	110.7	F37 Y219 H220 R222 V232 P234	F37-L58 HydrophobicContact CD1-CD1 4.29Å; F37-L58 HydrophobicContact CE1-CD1 4.23Å; F37-L58 HydrophobicContact CZ-CD1 4.42Å; L58-Y219 HydrophobicContact CD1-CD1 3.77Å; L58-Y219 HydrophobicContact CD1-CE1 4.48Å; L58-Y219 HydrophobicContact CD1-CG 4.34Å; L58-H220 PolarHBondContact N-O 2.91Å; L58-R222 PolarHBondContact O-N 3.06Å; L58-V232 HydrophobicContact CD2-CG1 3.79Å; L58-P234 HydrophobicContact CD1-CB 3.77Å; L58-P234 HydrophobicContact CD1-CG 3.71Å; L58-P234 HydrophobicContact CD2-CB 4.09Å; L58-P234 HydrophobicContact CD2-CG 4.41Å; L58-P234 HydrophobicContact CG-CB 4.3Å
59	D	44.8	Very low	48.3	Very low	43 Å²	43	86.4 Å²	86.4	23%	0.23	46%	0.461	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.7	135.2	166.1	-97.8	-53.5	0	0	0	109.8	F36 R223	F36-D59 PolarHBondContact O-N 2.86Å; D59-R223 WeakPolarHBondContact OD1-CG 3.28Å; D59-R223 IonicContact OD1-CZ 2.87Å; D59-R223 IonicContact OD1-NE 3.86Å; D59-R223 PolarHBondContact OD1-NE 2.83Å; D59-R223 IonicContact OD1-NH2 3.61Å
60	V	51.8	Low	49.9	Very low	10 Å²	10	79.3 Å²	79.3	6%	0.061	42%	0.424	C	S	.	.			trans	-124.6	125.6	-178.4	174.2	0	0	0	0	107.1	S64 A66 A67 I221 R223	V60-S64 WeakPolarHBondContact CG1-OG 3.39Å; V60-A66 HydrophobicContact CG1-CB 3.9Å; V60-A67 HydrophobicContact CG1-CB 4.24Å; V60-I221 HydrophobicContact CB-CG2 4.35Å; V60-I221 HydrophobicContact CG2-CD1 4.43Å; V60-I221 HydrophobicContact CG2-CG2 4.09Å; V60-R223 WeakPolarHBondContact O-CD 3.38Å
61	E	46.5	Very low	51.7	Low	141 Å²	141	74.1 Å²	74.1	66%	0.659	41%	0.409	S	S	*	.			trans	-68.5	143.5	-176.4	-154	152.9	-162.1	0	0	110.7	E63 S64	E61-E63 PolarHBondContact O-N 3.48Å; E61-S64 VanDerWaalsContact O-CB 3.22Å; E61-S64 WeakPolarHBondContact O-CB 3.25Å; E61-S64 PolarHBondContact O-N 2.78Å; E61-S64 PolarHBondContact O-OG 3.09Å
62	P	42.4	Very low	53.8	Low	103 Å²	103	63.4 Å²	63.4	67%	0.669	38%	0.375	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.4	-18.4	-166.2	23.9	-28.2	0	0	0	114.3
63	E	50.6	Low	56.4	Low	190 Å²	190	61.2 Å²	61.2	89%	0.888	36%	0.364	S	S	*	.	T	Hydrogen-bonded Turn	trans	-99.2	10.7	173.1	-60.4	-160.1	159.2	0	0	113.3	E61	E61-E63 PolarHBondContact O-N 3.48Å
64	S	56.9	Low	58.8	Low	21 Å²	21	59 Å²	59	15%	0.147	34%	0.343	C	S	.	.			trans	-74.3	142.4	-178.4	66.5	0	0	0	0	111.8	V60 E61 A66 A67 A68	V60-S64 WeakPolarHBondContact CG1-OG 3.39Å; E61-S64 VanDerWaalsContact O-CB 3.22Å; E61-S64 WeakPolarHBondContact O-CB 3.25Å; E61-S64 PolarHBondContact O-N 2.78Å; E61-S64 PolarHBondContact O-OG 3.09Å; S64-A66 PolarHBondContact O-N 3.31Å; S64-A67 PolarHBondContact O-N 3.01Å; S64-A68 PolarHBondContact O-N 3.21Å
65	P	59.4	Low	60.9	Low	61 Å²	61	51.1 Å²	51.1	40%	0.396	30%	0.302	S	S	.	.	H	α-helix	trans	-52.9	-25.7	174.2	-28.6	36.7	0	0	0	113.8	F33 Y69 D318	F33-P65 HydrophobicContact CD1-CB 3.9Å; F33-P65 HydrophobicContact CE1-CB 3.57Å; F33-P65 VanDerWaalsContact CE1-O 3.24Å; F33-P65 WeakPolarHBondContact CE1-O 3.48Å; P65-Y69 WeakPolarHBondContact O-CB 3.14Å; P65-Y69 PolarHBondContact O-N 3Å; P65-D318 WeakPolarHBondContact CG-OD1 3.22Å
66	A	60.6	Low	63	Low	2 Å²	2	50.2 Å²	50.2	2%	0.017	30%	0.297	C	S	.	.	H	α-helix	trans	-64.4	-51.3	179.1	0	0	0	0	0	113	F33 V60 S64 Y69 T70	F33-A66 HydrophobicContact CB-CB 3.32Å; F33-A66 HydrophobicContact CD1-CB 3.75Å; F33-A66 HydrophobicContact CD2-CB 4.1Å; F33-A66 HydrophobicContact CG-CB 3.47Å; F33-A66 VanDerWaalsContact CG-CB 3.47Å; V60-A66 HydrophobicContact CG1-CB 3.9Å; S64-A66 PolarHBondContact O-N 3.31Å; A66-Y69 PolarHBondContact O-N 3.27Å; A66-T70 WeakPolarHBondContact O-CG2 3.44Å; A66-T70 PolarHBondContact O-N 2.92Å; A66-T70 PolarHBondContact O-OG1 2.8Å; A66-T70 VanDerWaalsContact O-OG1 3.12Å
67	A	61.3	Low	64.9	Low	20 Å²	20	57.5 Å²	57.5	17%	0.165	32%	0.32	C	S	.	.	H	α-helix	trans	-66.5	-41.9	180	0	0	0	0	0	110.5	V60 S64 Y69 T70 T71	V60-A67 HydrophobicContact CG1-CB 4.24Å; S64-A67 PolarHBondContact O-N 3.01Å; A67-Y69 VanDerWaalsContact C-N 3.3Å; A67-Y69 PolarHBondContact O-N 3.03Å; A67-T70 WeakPolarHBondContact CA-OG1 3.5Å; A67-T70 PolarHBondContact O-N 3.36Å; A67-T70 PolarHBondContact O-OG1 3.42Å; A67-T70 VanDerWaalsContact O-OG1 3.08Å; A67-T71 PolarHBondContact O-N 3.47Å; A67-T71 VanDerWaalsContact O-N 3.08Å; A67-T71 PolarHBondContact O-OG1 2.84Å
68	A	67.7	Low	67	Low	65 Å²	65	58 Å²	58	54%	0.537	33%	0.325	S	S	.	.	H	α-helix	trans	-62.1	-36.3	176.4	0	0	0	0	0	112.8	S64 G72	S64-A68 PolarHBondContact O-N 3.21Å; A68-G72 VanDerWaalsContact O-CA 3.25Å; A68-G72 WeakPolarHBondContact O-CA 3.31Å; A68-G72 PolarHBondContact O-N 2.98Å
69	Y	72.1	Confident	69	Low	15 Å²	15	58 Å²	58	6%	0.059	33%	0.325	C	S	.	.	H	α-helix	trans	-72.6	-45.2	175.2	171.8	-90.1	0	0	0	112.6	F33 P65 A66 A67 T71 G72 I74 S75 I79 Y321 R325	F33-Y69 HydrophobicContact CD2-CD1 4.37Å; F33-Y69 VanDerWaalsContact CE2-CB 3.5Å; F33-Y69 AromaticContact CE2-CD1 3.42Å; F33-Y69 HydrophobicContact CE2-CD1 3.42Å; F33-Y69 VanDerWaalsContact CE2-CD1 3.42Å; F33-Y69 HydrophobicContact CE2-CD2 4.2Å; F33-Y69 HydrophobicContact CE2-CE1 4.18Å; F33-Y69 AromaticContact CE2-CG 3.43Å; F33-Y69 HydrophobicContact CE2-CG 3.43Å; F33-Y69 VanDerWaalsContact CE2-CG 3.43Å; F33-Y69 HydrophobicContact CZ-CD1 4.07Å; F33-Y69 HydrophobicContact CZ-CD2 4.13Å; F33-Y69 AromaticContact CZ-CG 3.57Å; F33-Y69 HydrophobicContact CZ-CG 3.57Å; P65-Y69 WeakPolarHBondContact O-CB 3.14Å; P65-Y69 PolarHBondContact O-N 3Å; A66-Y69 PolarHBondContact O-N 3.27Å; A67-Y69 VanDerWaalsContact C-N 3.3Å; A67-Y69 PolarHBondContact O-N 3.03Å; Y69-T71 VanDerWaalsContact C-N 3.29Å; Y69-T71 PolarHBondContact O-N 2.94Å; Y69-G72 PolarHBondContact O-N 3.17Å; Y69-G72 VanDerWaalsContact O-N 3.16Å; Y69-I74 HydrophobicContact CE2-CG2 4.05Å; Y69-S75 WeakPolarHBondContact O-CB 3.46Å; Y69-I79 WeakPolarHBondContact OH-CD1 3.44Å; Y69-Y321 HydrophobicContact CD1-CD1 4.49Å; Y69-Y321 HydrophobicContact CD1-CE1 4.17Å; Y69-Y321 HydrophobicContact CD2-CD1 4.28Å; Y69-Y321 HydrophobicContact CE1-CD1 4.36Å; Y69-Y321 AromaticContact CE1-CE1 3.71Å; Y69-Y321 HydrophobicContact CE1-CE1 3.71Å; Y69-Y321 HydrophobicContact CE2-CD1 4.12Å; Y69-Y321 HydrophobicContact CE2-CE1 4.1Å; Y69-Y321 HydrophobicContact CG-CD1 4.46Å; Y69-Y321 AromaticContact CZ-CE1 3.66Å; Y69-R325 HydrophobicContact CE2-CB 4.45Å; Y69-R325 HydrophobicContact CE2-CG 4.35Å; Y69-R325 WeakPolarHBondContact OH-CG 3.25Å
70	T	68.8	Low	71.3	Confident	5 Å²	5	56 Å²	56	3%	0.031	31%	0.314	C	S	.	.	H	α-helix	trans	-67.1	-29.8	-177.5	52.2	0	0	0	0	112.6	A66 A67 N141 T228	A66-T70 WeakPolarHBondContact O-CG2 3.44Å; A66-T70 PolarHBondContact O-N 2.92Å; A66-T70 PolarHBondContact O-OG1 2.8Å; A66-T70 VanDerWaalsContact O-OG1 3.12Å; A67-T70 WeakPolarHBondContact CA-OG1 3.5Å; A67-T70 PolarHBondContact O-N 3.36Å; A67-T70 PolarHBondContact O-OG1 3.42Å; A67-T70 VanDerWaalsContact O-OG1 3.08Å; T70-N141 PolarHBondContact O-ND2 3.38Å; T70-T228 HydrophobicContact CG2-CG2 4.48Å
71	T	72.7	Confident	73.4	Confident	95 Å²	95	58.8 Å²	58.8	58%	0.583	33%	0.334	S	S	*	.	H	α-helix	trans	-94.3	-9.7	172.9	62.1	0	0	0	0	113.2	A67 Y69 L224	A67-T71 PolarHBondContact O-N 3.47Å; A67-T71 VanDerWaalsContact O-N 3.08Å; A67-T71 PolarHBondContact O-OG1 2.84Å; Y69-T71 VanDerWaalsContact C-N 3.29Å; Y69-T71 PolarHBondContact O-N 2.94Å; T71-L224 HydrophobicContact CG2-CD2 4.36Å
72	G	79.5	Confident	75.7	Confident	21 Å²	21	52.8 Å²	52.8	22%	0.216	31%	0.308	C	S	.	.	S	Bend	trans	-75.3	156	-174.1	0	0	0	0	0	114.2	A68 Y69 I74 S75 T76	A68-G72 VanDerWaalsContact O-CA 3.25Å; A68-G72 WeakPolarHBondContact O-CA 3.31Å; A68-G72 PolarHBondContact O-N 2.98Å; Y69-G72 PolarHBondContact O-N 3.17Å; Y69-G72 VanDerWaalsContact O-N 3.16Å; G72-I74 PolarHBondContact O-N 2.86Å; G72-I74 VanDerWaalsContact O-N 3.16Å; G72-S75 PolarHBondContact O-N 3.49Å; G72-T76 PolarHBondContact O-N 3.16Å; G72-T76 PolarHBondContact O-OG1 3Å
73	A	84.1	Confident	78.2	Confident	62 Å²	62	47.9 Å²	47.9	51%	0.512	28%	0.276	S	S	.	.	H	α-helix	trans	-60.5	-25.8	-179.3	0	0	0	0	0	113.8	W77 I78	A73-W77 WeakPolarHBondContact O-CB 3.37Å; A73-W77 PolarHBondContact O-N 3.32Å; A73-I78 PolarHBondContact O-N 3.33Å; A73-I78 VanDerWaalsContact O-N 3.08Å
74	I	85.1	Confident	80.4	Confident	59 Å²	59	41.9 Å²	41.9	30%	0.303	25%	0.249	S	C	.	.	I	π-helix	trans	-59.5	-53.8	175.3	-64.8	171.9	0	0	0	109.8	Y69 G72 I78 I79 L326	Y69-I74 HydrophobicContact CE2-CG2 4.05Å; G72-I74 PolarHBondContact O-N 2.86Å; G72-I74 VanDerWaalsContact O-N 3.16Å; I74-I78 HydrophobicContact CG1-CD1 4.27Å; I74-I78 PolarHBondContact O-N 2.82Å; I74-I79 HydrophobicContact CG2-CD1 4.28Å; I74-I79 HydrophobicContact CG2-CG1 4.38Å; I74-I79 VanDerWaalsContact O-CG1 3.28Å; I74-I79 WeakPolarHBondContact O-CG1 3.49Å; I74-I79 PolarHBondContact O-N 3.01Å; I74-L326 HydrophobicContact CG2-CD2 3.94Å; I74-L326 HydrophobicContact CG2-CG 4.15Å
75	S	84.9	Confident	82.2	Confident	0 Å²	0	45.1 Å²	45.1	0%	0	26%	0.264	C	S	.	.	I	π-helix	trans	-74.4	-38.2	-175.3	-168.6	0	0	0	0	112.7	Y69 G72 P80 H137 N141	Y69-S75 WeakPolarHBondContact O-CB 3.46Å; G72-S75 PolarHBondContact O-N 3.49Å; S75-P80 VanDerWaalsContact O-CD 3.22Å; S75-P80 WeakPolarHBondContact O-CD 3.39Å; S75-H137 PolarHBondContact O-ND1 2.93Å; S75-H137 PolarHBondContact OG-ND1 3.37Å; S75-N141 PolarHBondContact OG-ND2 3Å; S75-N141 PolarHBondContact OG-OD1 3.46Å; S75-N141 VanDerWaalsContact OG-OD1 3.13Å
76	T	86.3	Confident	83.9	Confident	34 Å²	34	42.2 Å²	42.2	21%	0.209	25%	0.246	C	C	.	.	I	π-helix	trans	-90.3	-23.7	-171.4	52.4	0	0	0	0	114.7	G72 P80	G72-T76 PolarHBondContact O-N 3.16Å; G72-T76 PolarHBondContact O-OG1 3Å; T76-P80 WeakPolarHBondContact O-CG 3.23Å
77	W	88.7	Confident	85.6	Confident	186 Å²	186	43.6 Å²	43.6	71%	0.705	25%	0.252	S	S	*	.	I	π-helix	trans	-120.5	-57.8	-179.1	-67.2	81.5	0	0	0	112.3	A73 P80 S81	A73-W77 WeakPolarHBondContact O-CB 3.37Å; A73-W77 PolarHBondContact O-N 3.32Å; W77-P80 WeakPolarHBondContact O-CD 3.47Å; W77-P80 WeakPolarHBondContact O-CG 3.26Å; W77-S81 VanDerWaalsContact O-CB 3.29Å; W77-S81 WeakPolarHBondContact O-CB 3.32Å; W77-S81 PolarHBondContact O-N 3.32Å; W77-S81 PolarHBondContact O-OG 3.28Å
78	I	91.8	Very high	87.1	Confident	85 Å²	85	48.1 Å²	48.1	44%	0.436	27%	0.273	S	S	.	.	I	π-helix	trans	-65.3	-50.1	-169.2	-58.4	177.9	0	0	0	111.4	A73 I74 S82 L326	A73-I78 PolarHBondContact O-N 3.33Å; A73-I78 VanDerWaalsContact O-N 3.08Å; I74-I78 HydrophobicContact CG1-CD1 4.27Å; I74-I78 PolarHBondContact O-N 2.82Å; I78-S82 WeakPolarHBondContact O-CB 3.16Å; I78-S82 PolarHBondContact O-N 3.29Å; I78-S82 PolarHBondContact O-OG 3.43Å; I78-L326 HydrophobicContact CB-CD2 4.43Å; I78-L326 HydrophobicContact CG2-CD2 3.64Å
79	I	92.4	Very high	88.3	Confident	0 Å²	0	47.7 Å²	47.7	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-59.2	-57.2	179	-67	178.9	0	0	0	111.6	Y69 I74 S81 S82 Y83 R325	Y69-I79 WeakPolarHBondContact OH-CD1 3.44Å; I74-I79 HydrophobicContact CG2-CD1 4.28Å; I74-I79 HydrophobicContact CG2-CG1 4.38Å; I74-I79 VanDerWaalsContact O-CG1 3.28Å; I74-I79 WeakPolarHBondContact O-CG1 3.49Å; I74-I79 PolarHBondContact O-N 3.01Å; I79-S81 PolarHBondContact O-N 3.05Å; I79-S82 PolarHBondContact O-N 3.09Å; I79-S82 PolarHBondContact O-OG 3.18Å; I79-Y83 HydrophobicContact CG2-CD2 3.84Å; I79-Y83 HydrophobicContact CG2-CE1 4.11Å; I79-Y83 HydrophobicContact CG2-CE2 3.31Å; I79-Y83 HydrophobicContact CG2-CG 4.43Å; I79-Y83 VanDerWaalsContact CG2-CZ 3.46Å; I79-Y83 PolarHBondContact O-N 3.35Å; I79-R325 HydrophobicContact CD1-CB 3.93Å
80	P	94	Very high	89.2	Confident	1 Å²	1	47 Å²	47	1%	0.006	26%	0.261	C	S	.	.	H	α-helix	trans	-62.1	-38.7	-178.6	19.6	-30	0	0	0	112.9	S75 T76 W77 S82 Y83 I84 H137 L138	S75-P80 VanDerWaalsContact O-CD 3.22Å; S75-P80 WeakPolarHBondContact O-CD 3.39Å; T76-P80 WeakPolarHBondContact O-CG 3.23Å; W77-P80 WeakPolarHBondContact O-CD 3.47Å; W77-P80 WeakPolarHBondContact O-CG 3.26Å; P80-S82 VanDerWaalsContact C-N 3.34Å; P80-S82 PolarHBondContact O-N 3.5Å; P80-Y83 PolarHBondContact O-N 3.3Å; P80-I84 WeakPolarHBondContact O-CB 3.41Å; P80-I84 VanDerWaalsContact O-CG1 3.24Å; P80-I84 WeakPolarHBondContact O-CG1 3.45Å; P80-I84 PolarHBondContact O-N 3.22Å; P80-H137 HydrophobicContact CB-CB 3.94Å; P80-H137 HydrophobicContact CG-CB 3.88Å; P80-L138 HydrophobicContact CB-CD2 4.11Å; P80-L138 HydrophobicContact CB-CG 4.32Å; P80-L138 HydrophobicContact CG-CD2 4.38Å
81	S	95.3	Very high	90.3	Very high	68 Å²	68	50.2 Å²	50.2	48%	0.476	28%	0.277	S	S	.	.	H	α-helix	trans	-60.4	-42.6	175.1	-65.7	0	0	0	0	112.3	W77 I79 Y83 I84 L85	W77-S81 VanDerWaalsContact O-CB 3.29Å; W77-S81 WeakPolarHBondContact O-CB 3.32Å; W77-S81 PolarHBondContact O-N 3.32Å; W77-S81 PolarHBondContact O-OG 3.28Å; I79-S81 PolarHBondContact O-N 3.05Å; S81-Y83 VanDerWaalsContact C-N 3.35Å; S81-Y83 PolarHBondContact O-N 3.16Å; S81-I84 PolarHBondContact O-N 3.44Å; S81-L85 PolarHBondContact O-N 3.41Å
82	S	95.4	Very high	91.2	Very high	15 Å²	15	49.4 Å²	49.4	11%	0.105	27%	0.273	C	S	.	.	H	α-helix	trans	-64.9	-38.4	177.3	75.9	0	0	0	0	112.7	I78 I79 P80 L85 T86 C329	I78-S82 WeakPolarHBondContact O-CB 3.16Å; I78-S82 PolarHBondContact O-N 3.29Å; I78-S82 PolarHBondContact O-OG 3.43Å; I79-S82 PolarHBondContact O-N 3.09Å; I79-S82 PolarHBondContact O-OG 3.18Å; P80-S82 VanDerWaalsContact C-N 3.34Å; P80-S82 PolarHBondContact O-N 3.5Å; S82-L85 PolarHBondContact O-N 3.3Å; S82-T86 PolarHBondContact O-N 2.88Å; S82-T86 PolarHBondContact O-OG1 3.27Å; S82-C329 VanDerWaalsContact OG-CB 3.29Å; S82-C329 WeakPolarHBondContact OG-CB 3.04Å; S82-C329 PolarHBondContact OG-SG 2.76Å; S82-C329 VanDerWaalsContact OG-SG 3.35Å
83	Y	95.3	Very high	91.6	Very high	0 Å²	0	49.2 Å²	49.2	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-69.5	-42	177.3	-67.7	-8.9	0	0	0	111.5	I79 P80 S81 L85 T86 I87 L130 R133 V134 C329	I79-Y83 HydrophobicContact CG2-CD2 3.84Å; I79-Y83 HydrophobicContact CG2-CE1 4.11Å; I79-Y83 HydrophobicContact CG2-CE2 3.31Å; I79-Y83 HydrophobicContact CG2-CG 4.43Å; I79-Y83 VanDerWaalsContact CG2-CZ 3.46Å; I79-Y83 PolarHBondContact O-N 3.35Å; P80-Y83 PolarHBondContact O-N 3.3Å; S81-Y83 VanDerWaalsContact C-N 3.35Å; S81-Y83 PolarHBondContact O-N 3.16Å; Y83-L85 VanDerWaalsContact C-N 3.35Å; Y83-L85 PolarHBondContact O-N 3.05Å; Y83-T86 WeakPolarHBondContact O-CB 3.42Å; Y83-T86 PolarHBondContact O-N 3.25Å; Y83-I87 VanDerWaalsContact O-CG1 3.26Å; Y83-I87 WeakPolarHBondContact O-CG1 3.42Å; Y83-I87 PolarHBondContact O-N 2.9Å; Y83-L130 HydrophobicContact CD1-CD2 3.54Å; Y83-L130 HydrophobicContact CD2-CD2 3.94Å; Y83-L130 HydrophobicContact CE1-CD2 3.84Å; Y83-L130 HydrophobicContact CE2-CD2 4.21Å; Y83-L130 HydrophobicContact CG-CD2 3.6Å; Y83-R133 HydrophobicContact CD2-CB 4.13Å; Y83-R133 HydrophobicContact CE2-CB 4.04Å; Y83-V134 VanDerWaalsContact CB-CG2 3.45Å; Y83-V134 HydrophobicContact CD2-CG2 4.39Å; Y83-V134 HydrophobicContact CG-CG2 4.46Å; Y83-C329 HydrophobicContact CE1-CB 4.4Å
84	I	96.1	Very high	91.9	Very high	65 Å²	65	46.3 Å²	46.3	33%	0.333	25%	0.245	S	C	.	.	H	α-helix	trans	-58.8	-47.4	173.4	-69.5	164.3	0	0	0	110.2	P80 S81 T86 I87 L88 V134	P80-I84 WeakPolarHBondContact O-CB 3.41Å; P80-I84 VanDerWaalsContact O-CG1 3.24Å; P80-I84 WeakPolarHBondContact O-CG1 3.45Å; P80-I84 PolarHBondContact O-N 3.22Å; S81-I84 PolarHBondContact O-N 3.44Å; I84-T86 VanDerWaalsContact C-N 3.3Å; I84-T86 PolarHBondContact O-N 3.37Å; I84-I87 PolarHBondContact O-N 3.29Å; I84-I87 VanDerWaalsContact O-N 3.15Å; I84-L88 HydrophobicContact CG2-CD1 3.87Å; I84-L88 HydrophobicContact CG2-CG 4.2Å; I84-L88 WeakPolarHBondContact O-CB 2.99Å; I84-L88 VanDerWaalsContact O-CG 3.3Å; I84-L88 WeakPolarHBondContact O-CG 3.27Å; I84-L88 PolarHBondContact O-N 3.13Å; I84-V134 HydrophobicContact CD1-CG1 3.9Å; I84-V134 HydrophobicContact CG1-CB 4.47Å; I84-V134 HydrophobicContact CG1-CG1 3.68Å; I84-V134 HydrophobicContact CG1-CG2 3.89Å
85	L	95.6	Very high	92.1	Very high	89 Å²	89	47 Å²	47	47%	0.466	25%	0.252	S	S	.	.	H	α-helix	trans	-60.2	-42.5	177.7	-175.9	61.1	0	0	0	111.6	S81 S82 Y83 I87 L88 V89 F333	S81-L85 PolarHBondContact O-N 3.41Å; S82-L85 PolarHBondContact O-N 3.3Å; Y83-L85 VanDerWaalsContact C-N 3.35Å; Y83-L85 PolarHBondContact O-N 3.05Å; L85-I87 VanDerWaalsContact C-N 3.34Å; L85-I87 PolarHBondContact O-N 3.44Å; L85-L88 PolarHBondContact O-N 2.95Å; L85-V89 HydrophobicContact CD1-CG2 4.28Å; L85-V89 WeakPolarHBondContact O-CG2 3.41Å; L85-V89 PolarHBondContact O-N 2.69Å; L85-V89 VanDerWaalsContact O-N 3.07Å; L85-F333 HydrophobicContact CB-CE1 4.06Å; L85-F333 HydrophobicContact CB-CZ 4.35Å; L85-F333 HydrophobicContact CD2-CE1 3.61Å; L85-F333 HydrophobicContact CD2-CZ 3.87Å; L85-F333 HydrophobicContact CG-CE1 3.78Å; L85-F333 HydrophobicContact CG-CZ 4.35Å
86	T	94.6	Very high	92.2	Very high	0 Å²	0	53 Å²	53	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-61.3	-41.4	175.5	-56.3	0	0	0	0	111.6	S82 Y83 I84 G90 L130 C332 S335	S82-T86 PolarHBondContact O-N 2.88Å; S82-T86 PolarHBondContact O-OG1 3.27Å; Y83-T86 WeakPolarHBondContact O-CB 3.42Å; Y83-T86 PolarHBondContact O-N 3.25Å; I84-T86 VanDerWaalsContact C-N 3.3Å; I84-T86 PolarHBondContact O-N 3.37Å; T86-G90 VanDerWaalsContact O-CA 3.23Å; T86-G90 WeakPolarHBondContact O-CA 3.36Å; T86-G90 PolarHBondContact O-N 3.4Å; T86-L130 HydrophobicContact CG2-CD1 3.6Å; T86-C332 HydrophobicContact CG2-CB 4.12Å; T86-C332 WeakPolarHBondContact CG2-O 3.17Å; T86-S335 WeakPolarHBondContact CG2-OG 3.31Å
87	I	95.1	Very high	92.2	Very high	30 Å²	30	51.6 Å²	51.6	15%	0.154	27%	0.266	C	S	.	.	H	α-helix	trans	-65.1	-47.1	176.9	-68.9	164.2	0	0	0	110.8	Y83 I84 L85 V89 G90 I91 V127 L130 A131 V134	Y83-I87 VanDerWaalsContact O-CG1 3.26Å; Y83-I87 WeakPolarHBondContact O-CG1 3.42Å; Y83-I87 PolarHBondContact O-N 2.9Å; I84-I87 PolarHBondContact O-N 3.29Å; I84-I87 VanDerWaalsContact O-N 3.15Å; L85-I87 VanDerWaalsContact C-N 3.34Å; L85-I87 PolarHBondContact O-N 3.44Å; I87-V89 VanDerWaalsContact C-N 3.29Å; I87-V89 PolarHBondContact O-N 2.93Å; I87-G90 PolarHBondContact O-N 3.33Å; I87-I91 HydrophobicContact CG2-CD1 3.64Å; I87-I91 HydrophobicContact CG2-CG1 4.32Å; I87-I91 WeakPolarHBondContact O-CG1 3.3Å; I87-I91 PolarHBondContact O-N 2.92Å; I87-V127 HydrophobicContact CG1-CG1 4.21Å; I87-V127 HydrophobicContact CG2-CG1 4.25Å; I87-L130 HydrophobicContact CD1-CB 3.91Å; I87-L130 HydrophobicContact CG1-CB 3.93Å; I87-L130 HydrophobicContact CG1-CD1 4.46Å; I87-A131 HydrophobicContact CD1-CB 4.21Å; I87-V134 HydrophobicContact CD1-CG2 4.05Å
88	L	94.8	Very high	92.2	Very high	115 Å²	115	45.6 Å²	45.6	60%	0.602	25%	0.248	S	C	*	.	H	α-helix	trans	-60.6	-37.3	-177.7	-74.3	175.4	0	0	0	112.5	I84 L85 P92	I84-L88 HydrophobicContact CG2-CD1 3.87Å; I84-L88 HydrophobicContact CG2-CG 4.2Å; I84-L88 WeakPolarHBondContact O-CB 2.99Å; I84-L88 VanDerWaalsContact O-CG 3.3Å; I84-L88 WeakPolarHBondContact O-CG 3.27Å; I84-L88 PolarHBondContact O-N 3.13Å; L85-L88 PolarHBondContact O-N 2.95Å; L88-P92 WeakPolarHBondContact O-CD 3.45Å; L88-P92 VanDerWaalsContact O-CG 3.22Å; L88-P92 WeakPolarHBondContact O-CG 3.31Å
89	V	92.4	Very high	92	Very high	56 Å²	56	44 Å²	44	34%	0.339	25%	0.247	S	C	.	.	H	α-helix	trans	-89.5	-39.9	178.3	-179.6	0	0	0	0	111.3	L85 I87 P92 S93 C336	L85-V89 HydrophobicContact CD1-CG2 4.28Å; L85-V89 WeakPolarHBondContact O-CG2 3.41Å; L85-V89 PolarHBondContact O-N 2.69Å; L85-V89 VanDerWaalsContact O-N 3.07Å; I87-V89 VanDerWaalsContact C-N 3.29Å; I87-V89 PolarHBondContact O-N 2.93Å; V89-P92 WeakPolarHBondContact O-CD 3.44Å; V89-S93 WeakPolarHBondContact O-CB 3.37Å; V89-S93 PolarHBondContact O-N 3.42Å; V89-S93 VanDerWaalsContact O-N 3.11Å; V89-S93 PolarHBondContact O-OG 2.85Å; V89-C336 HydrophobicContact CB-CB 4.27Å; V89-C336 HydrophobicContact CG1-CB 3.63Å
90	G	90.6	Very high	91.5	Very high	0 Å²	0	46.5 Å²	46.5	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-67.1	-39.5	-174.4	0	0	0	0	0	114	T86 I87 N94	T86-G90 VanDerWaalsContact O-CA 3.23Å; T86-G90 WeakPolarHBondContact O-CA 3.36Å; T86-G90 PolarHBondContact O-N 3.4Å; I87-G90 PolarHBondContact O-N 3.33Å; G90-N94 WeakPolarHBondContact O-CB 3.4Å; G90-N94 PolarHBondContact O-N 3.39Å; G90-N94 PolarHBondContact O-ND2 2.98Å
91	I	91.5	Very high	90.9	Very high	74 Å²	74	46.8 Å²	46.8	38%	0.379	26%	0.26	S	S	.	.	H	α-helix	trans	-64.1	-55.2	177.9	-69.1	173.2	0	0	0	111.6	I87 S93 N94 T95 V127	I87-I91 HydrophobicContact CG2-CD1 3.64Å; I87-I91 HydrophobicContact CG2-CG1 4.32Å; I87-I91 WeakPolarHBondContact O-CG1 3.3Å; I87-I91 PolarHBondContact O-N 2.92Å; I91-S93 VanDerWaalsContact C-N 3.28Å; I91-S93 PolarHBondContact O-N 3.18Å; I91-N94 PolarHBondContact O-N 3.19Å; I91-T95 VanDerWaalsContact O-CB 3.26Å; I91-T95 WeakPolarHBondContact O-CB 3.26Å; I91-T95 PolarHBondContact O-N 2.85Å; I91-T95 PolarHBondContact O-OG1 3.36Å; I91-V127 HydrophobicContact CD1-CG1 3.71Å; I91-V127 HydrophobicContact CG1-CG1 3.42Å; I91-V127 VanDerWaalsContact CG1-CG1 3.42Å; I91-V127 HydrophobicContact CG1-CG2 4.5Å
92	P	91	Very high	90.3	Very high	77 Å²	77	53.8 Å²	53.8	50%	0.5	28%	0.276	S	S	.	.	H	α-helix	trans	-59.4	-41.3	178	-24.8	34.6	0	0	0	112.1	L88 V89 T95 Y96	L88-P92 WeakPolarHBondContact O-CD 3.45Å; L88-P92 VanDerWaalsContact O-CG 3.22Å; L88-P92 WeakPolarHBondContact O-CG 3.31Å; V89-P92 WeakPolarHBondContact O-CD 3.44Å; P92-T95 PolarHBondContact O-N 3.1Å; P92-Y96 VanDerWaalsContact O-CB 3.28Å; P92-Y96 WeakPolarHBondContact O-CB 3.11Å; P92-Y96 PolarHBondContact O-N 3.23Å
93	S	88.9	Confident	89.6	Confident	18 Å²	18	58.7 Å²	58.7	13%	0.126	31%	0.305	C	S	.	.	H	α-helix	trans	-56.4	-53.8	177.7	-72.6	0	0	0	0	112.6	V89 I91 Y96 I97 P339	V89-S93 WeakPolarHBondContact O-CB 3.37Å; V89-S93 PolarHBondContact O-N 3.42Å; V89-S93 VanDerWaalsContact O-N 3.11Å; V89-S93 PolarHBondContact O-OG 2.85Å; I91-S93 VanDerWaalsContact C-N 3.28Å; I91-S93 PolarHBondContact O-N 3.18Å; S93-Y96 WeakPolarHBondContact O-CB 3.17Å; S93-Y96 PolarHBondContact O-N 3.2Å; S93-I97 WeakPolarHBondContact O-CG1 3.33Å; S93-I97 PolarHBondContact O-N 3.17Å; S93-I97 VanDerWaalsContact O-N 3.12Å; S93-P339 WeakPolarHBondContact OG-CG 3.47Å
94	N	89.6	Confident	88.5	Confident	0 Å²	0	65.3 Å²	65.3	0%	0	33%	0.33	C	S	.	.	H	α-helix	trans	-73.4	-32.1	-177.9	-79.8	-72.1	0	0	0	112.6	G90 I91 I97 L98 D123 L124	G90-N94 WeakPolarHBondContact O-CB 3.4Å; G90-N94 PolarHBondContact O-N 3.39Å; G90-N94 PolarHBondContact O-ND2 2.98Å; I91-N94 PolarHBondContact O-N 3.19Å; N94-I97 PolarHBondContact O-N 3.2Å; N94-L98 WeakPolarHBondContact O-CG 3.44Å; N94-L98 PolarHBondContact O-N 3.37Å; N94-L98 VanDerWaalsContact O-N 3.11Å; N94-D123 VanDerWaalsContact CG-CB 3.43Å; N94-D123 VanDerWaalsContact ND2-CB 3.26Å; N94-D123 WeakPolarHBondContact ND2-CB 3.41Å; N94-D123 PolarHBondContact ND2-OD2 2.87Å; N94-D123 WeakPolarHBondContact OD1-CB 3.4Å; N94-D123 PolarHBondContact OD1-OD2 2.86Å; N94-L124 HydrophobicContact CB-CD2 4.48Å
95	T	89.1	Confident	87.2	Confident	74 Å²	74	66.8 Å²	66.8	45%	0.454	34%	0.338	S	S	.	.	H	α-helix	trans	-66.7	-39.1	172.7	-59.6	0	0	0	0	111.2	I91 P92 L98 A99	I91-T95 VanDerWaalsContact O-CB 3.26Å; I91-T95 WeakPolarHBondContact O-CB 3.26Å; I91-T95 PolarHBondContact O-N 2.85Å; I91-T95 PolarHBondContact O-OG1 3.36Å; P92-T95 PolarHBondContact O-N 3.1Å; T95-L98 PolarHBondContact O-N 2.99Å; T95-A99 WeakPolarHBondContact O-CB 3.28Å; T95-A99 PolarHBondContact O-N 2.94Å
96	Y	87.8	Confident	85.6	Confident	126 Å²	126	69.8 Å²	69.8	49%	0.494	36%	0.36	S	S	.	.	H	α-helix	trans	-60.6	-44.1	173.4	173.6	-95.3	0	0	0	111.7	P92 S93 L98 A99 F100	P92-Y96 VanDerWaalsContact O-CB 3.28Å; P92-Y96 WeakPolarHBondContact O-CB 3.11Å; P92-Y96 PolarHBondContact O-N 3.23Å; S93-Y96 WeakPolarHBondContact O-CB 3.17Å; S93-Y96 PolarHBondContact O-N 3.2Å; Y96-L98 VanDerWaalsContact C-N 3.34Å; Y96-L98 PolarHBondContact O-N 3.06Å; Y96-A99 PolarHBondContact O-N 3.46Å; Y96-F100 VanDerWaalsContact O-CB 3.23Å; Y96-F100 WeakPolarHBondContact O-CB 3.45Å; Y96-F100 PolarHBondContact O-N 2.88Å
97	I	86.7	Confident	84.2	Confident	4 Å²	4	73.3 Å²	73.3	2%	0.021	39%	0.385	C	S	.	.	H	α-helix	trans	-58.5	-46.8	176.4	-67	166.8	0	0	0	110.7	S93 N94 F100 L101 D338 P339 C342	S93-I97 WeakPolarHBondContact O-CG1 3.33Å; S93-I97 PolarHBondContact O-N 3.17Å; S93-I97 VanDerWaalsContact O-N 3.12Å; N94-I97 PolarHBondContact O-N 3.2Å; I97-F100 PolarHBondContact O-N 3.26Å; I97-L101 HydrophobicContact CG2-CD1 4.36Å; I97-L101 WeakPolarHBondContact O-CB 3.39Å; I97-L101 WeakPolarHBondContact O-CG 3.22Å; I97-L101 PolarHBondContact O-N 3.08Å; I97-D338 HydrophobicContact CD1-CB 4.44Å; I97-P339 HydrophobicContact CD1-CG 4.28Å; I97-C342 HydrophobicContact CD1-CB 4.42Å; I97-C342 HydrophobicContact CG1-CB 4.35Å
98	L	88.2	Confident	83	Confident	61 Å²	61	74 Å²	74	32%	0.319	39%	0.386	S	S	.	.	H	α-helix	trans	-64.7	-42.7	178.7	-68.1	175.1	0	0	0	112.5	N94 T95 Y96 L101 R102 L117 A120 L124	N94-L98 WeakPolarHBondContact O-CG 3.44Å; N94-L98 PolarHBondContact O-N 3.37Å; N94-L98 VanDerWaalsContact O-N 3.11Å; T95-L98 PolarHBondContact O-N 2.99Å; Y96-L98 VanDerWaalsContact C-N 3.34Å; Y96-L98 PolarHBondContact O-N 3.06Å; L98-L101 PolarHBondContact O-N 2.9Å; L98-R102 PolarHBondContact O-N 2.72Å; L98-L117 HydrophobicContact CD2-CD2 3.84Å; L98-A120 HydrophobicContact CD1-CB 4.34Å; L98-A120 HydrophobicContact CD2-CB 3.64Å; L98-A120 HydrophobicContact CG-CB 3.85Å; L98-L124 HydrophobicContact CD1-CD1 3.99Å
99	A	87.1	Confident	82.1	Confident	51 Å²	51	72.2 Å²	72.2	42%	0.421	38%	0.381	S	S	.	.	H	α-helix	trans	-63.7	-44.1	175.8	0	0	0	0	0	111.6	T95 Y96 L101 R102 V103	T95-A99 WeakPolarHBondContact O-CB 3.28Å; T95-A99 PolarHBondContact O-N 2.94Å; Y96-A99 PolarHBondContact O-N 3.46Å; A99-L101 PolarHBondContact O-N 3.28Å; A99-R102 WeakPolarHBondContact O-CB 3.46Å; A99-R102 PolarHBondContact O-N 2.8Å; A99-V103 WeakPolarHBondContact O-CG2 3.47Å; A99-V103 PolarHBondContact O-N 3.16Å
100	F	82.4	Confident	81.4	Confident	53 Å²	53	75.1 Å²	75.1	23%	0.232	39%	0.394	C	S	.	.	H	α-helix	trans	-59.3	-45.3	176	175.7	-98.1	0	0	0	111.7	Y96 I97 R102 V103 R104	Y96-F100 VanDerWaalsContact O-CB 3.23Å; Y96-F100 WeakPolarHBondContact O-CB 3.45Å; Y96-F100 PolarHBondContact O-N 2.88Å; I97-F100 PolarHBondContact O-N 3.26Å; F100-R102 PolarHBondContact O-N 3.03Å; F100-V103 PolarHBondContact O-N 3.19Å; F100-R104 HydrophobicContact CD2-CG 4.34Å; F100-R104 HydrophobicContact CE2-CG 3.98Å; F100-R104 HydrophobicContact CZ-CG 4.2Å; F100-R104 WeakPolarHBondContact O-CB 3.24Å; F100-R104 PolarHBondContact O-N 3.05Å
101	L	82.1	Confident	80.9	Confident	6 Å²	6	75.1 Å²	75.1	3%	0.031	39%	0.394	C	S	.	.	H	α-helix	trans	-59.4	-44.4	174.5	-77.9	175.2	0	0	0	112	I97 L98 A99 V103 R104 L105 V113 Y116 L117	I97-L101 HydrophobicContact CG2-CD1 4.36Å; I97-L101 WeakPolarHBondContact O-CB 3.39Å; I97-L101 WeakPolarHBondContact O-CG 3.22Å; I97-L101 PolarHBondContact O-N 3.08Å; L98-L101 PolarHBondContact O-N 2.9Å; A99-L101 PolarHBondContact O-N 3.28Å; L101-V103 VanDerWaalsContact C-N 3.35Å; L101-V103 PolarHBondContact O-N 3.03Å; L101-R104 PolarHBondContact O-N 3.43Å; L101-L105 WeakPolarHBondContact O-CA 3.17Å; L101-L105 WeakPolarHBondContact O-CB 3.26Å; L101-L105 WeakPolarHBondContact O-CD1 3.42Å; L101-L105 PolarHBondContact O-N 2.78Å; L101-V113 HydrophobicContact CD2-CG2 4.29Å; L101-Y116 HydrophobicContact CD2-CD2 3.78Å; L101-Y116 HydrophobicContact CD2-CG 4.38Å; L101-Y116 HydrophobicContact CG-CD2 4.32Å; L101-L117 HydrophobicContact CD1-CD2 3.96Å; L101-L117 HydrophobicContact CD1-CG 4.05Å
102	R	82.9	Confident	80.3	Confident	216 Å²	216	72.9 Å²	72.9	82%	0.815	38%	0.383	S	S	*	.	H	α-helix	trans	-60.7	-43.1	179.6	-174.5	178.3	179.9	173.7	0.2	112	L98 A99 F100	L98-R102 PolarHBondContact O-N 2.72Å; A99-R102 WeakPolarHBondContact O-CB 3.46Å; A99-R102 PolarHBondContact O-N 2.8Å; F100-R102 PolarHBondContact O-N 3.03Å
103	V	81	Confident	79.9	Confident	117 Å²	117	70 Å²	70	71%	0.709	36%	0.364	S	S	*	.	H	α-helix	trans	-73	-34.7	-179.1	174.5	0	0	0	0	112.1	A99 F100 L101	A99-V103 WeakPolarHBondContact O-CG2 3.47Å; A99-V103 PolarHBondContact O-N 3.16Å; F100-V103 PolarHBondContact O-N 3.19Å; L101-V103 VanDerWaalsContact C-N 3.35Å; L101-V103 PolarHBondContact O-N 3.03Å
104	R	71.3	Confident	79.7	Confident	139 Å²	139	71.2 Å²	71.2	53%	0.525	37%	0.371	S	S	.	.	H	α-helix	trans	-104.8	12.2	-173.1	-64.9	-65.8	-170.2	152.1	0.2	114.1	F100 L101 T106 S107 K108	F100-R104 HydrophobicContact CD2-CG 4.34Å; F100-R104 HydrophobicContact CE2-CG 3.98Å; F100-R104 HydrophobicContact CZ-CG 4.2Å; F100-R104 WeakPolarHBondContact O-CB 3.24Å; F100-R104 PolarHBondContact O-N 3.05Å; L101-R104 PolarHBondContact O-N 3.43Å; R104-T106 VanDerWaalsContact C-N 3.28Å; R104-T106 PolarHBondContact O-N 3.08Å; R104-S107 PolarHBondContact O-N 3.43Å; R104-S107 PolarHBondContact O-OG 3.48Å; R104-K108 HydrophobicContact CB-CG 4.31Å; R104-K108 PolarHBondContact O-N 2.97Å
105	L	68.9	Low	79.4	Confident	97 Å²	97	72.1 Å²	72.1	51%	0.508	38%	0.376	S	S	.	.	G	3₁₀ helix	trans	-54.4	-41.9	-172.4	-154.2	73.3	0	0	0	112.6	L101 S107 V113	L101-L105 WeakPolarHBondContact O-CA 3.17Å; L101-L105 WeakPolarHBondContact O-CB 3.26Å; L101-L105 WeakPolarHBondContact O-CD1 3.42Å; L101-L105 PolarHBondContact O-N 2.78Å; L105-S107 PolarHBondContact O-N 3.4Å; L105-V113 HydrophobicContact CD1-CG1 3.96Å; L105-V113 HydrophobicContact CD1-CG2 4.15Å
106	T	62.3	Low	79.2	Confident	151 Å²	151	69.1 Å²	69.1	93%	0.926	36%	0.356	S	S	*	.	G	3₁₀ helix	trans	-69.5	-20.1	-179.9	-39.1	0	0	0	0	113.5	R104	R104-T106 VanDerWaalsContact C-N 3.28Å; R104-T106 PolarHBondContact O-N 3.08Å
107	S	65.3	Low	79.1	Confident	75 Å²	75	67.1 Å²	67.1	52%	0.524	35%	0.354	S	S	.	.	G	3₁₀ helix	trans	-102.1	-7.6	-175	67.1	0	0	0	0	114.3	R104 L105	R104-S107 PolarHBondContact O-N 3.43Å; R104-S107 PolarHBondContact O-OG 3.48Å; L105-S107 PolarHBondContact O-N 3.4Å
108	K	69.6	Low	79.2	Confident	43 Å²	43	67.4 Å²	67.4	19%	0.187	36%	0.355	C	S	.	.	S	Bend	trans	-109.8	146.7	-174.1	-66.8	-61.5	-178.2	-171.8	0	111.5	R104 V113	R104-K108 HydrophobicContact CB-CG 4.31Å; R104-K108 PolarHBondContact O-N 2.97Å; K108-V113 HydrophobicContact CB-CG2 4.17Å
109	T	74.8	Confident	79.2	Confident	78 Å²	78	64.7 Å²	64.7	48%	0.479	34%	0.341	S	S	.	.			trans	-66.6	143.7	175.7	74.5	0	0	0	0	110.4	S111 T112 V113	T109-S111 PolarHBondContact O-N 3.45Å; T109-S111 VanDerWaalsContact O-N 3.14Å; T109-T112 WeakPolarHBondContact O-CB 3.47Å; T109-T112 PolarHBondContact O-N 3.38Å; T109-T112 PolarHBondContact OG1-N 3.04Å; T109-T112 PolarHBondContact OG1-OG1 3.39Å; T109-T112 VanDerWaalsContact OG1-OG1 3.09Å; T109-V113 PolarHBondContact O-N 2.85Å; T109-V113 VanDerWaalsContact O-N 3.16Å
110	L	78.3	Confident	79.3	Confident	117 Å²	117	62.3 Å²	62.3	61%	0.613	32%	0.321	S	S	*	.	H	α-helix	trans	-53.6	-34.8	175.9	-67.1	175.5	0	0	0	112.3	T112 V113 V114 T191	L110-T112 VanDerWaalsContact C-N 3.34Å; L110-T112 PolarHBondContact O-N 2.95Å; L110-V113 PolarHBondContact O-N 3.27Å; L110-V114 VanDerWaalsContact O-CG2 3.3Å; L110-V114 WeakPolarHBondContact O-CG2 3.31Å; L110-V114 PolarHBondContact O-N 3.12Å; L110-T191 HydrophobicContact CB-CG2 3.69Å; L110-T191 HydrophobicContact CD1-CG2 4.49Å
111	S	79.7	Confident	79.6	Confident	0 Å²	0	64.1 Å²	64.1	0%	0	33%	0.333	C	S	.	.	H	α-helix	trans	-57.1	-42.5	173.8	-175.3	0	0	0	0	113.2	T109 L115 K174 K190 A194	T109-S111 PolarHBondContact O-N 3.45Å; T109-S111 VanDerWaalsContact O-N 3.14Å; S111-L115 WeakPolarHBondContact O-CG 3.3Å; S111-L115 PolarHBondContact O-N 2.79Å; S111-K174 PolarHBondContact OG-NZ 2.99Å; S111-K174 VanDerWaalsContact OG-NZ 3.13Å; S111-K190 WeakPolarHBondContact CB-O 3.24Å; S111-K190 PolarHBondContact OG-O 3.49Å; S111-A194 WeakPolarHBondContact OG-CB 3.35Å
112	T	79	Confident	80	Confident	27 Å²	27	63.8 Å²	63.8	17%	0.166	33%	0.331	C	S	.	.	H	α-helix	trans	-71.9	-42.2	178.8	-56.5	0	0	0	0	111.1	T109 L110 V114 L115 Y116	T109-T112 WeakPolarHBondContact O-CB 3.47Å; T109-T112 PolarHBondContact O-N 3.38Å; T109-T112 PolarHBondContact OG1-N 3.04Å; T109-T112 PolarHBondContact OG1-OG1 3.39Å; T109-T112 VanDerWaalsContact OG1-OG1 3.09Å; L110-T112 VanDerWaalsContact C-N 3.34Å; L110-T112 PolarHBondContact O-N 2.95Å; T112-V114 PolarHBondContact O-N 3.46Å; T112-L115 PolarHBondContact O-N 3.44Å; T112-Y116 HydrophobicContact CG2-CD1 4.49Å; T112-Y116 HydrophobicContact CG2-CD2 4.01Å; T112-Y116 HydrophobicContact CG2-CE1 4.13Å; T112-Y116 HydrophobicContact CG2-CE2 3.64Å; T112-Y116 HydrophobicContact CG2-CG 4.42Å; T112-Y116 PolarHBondContact O-N 2.77Å; T112-Y116 VanDerWaalsContact O-N 3.07Å
113	V	83.1	Confident	80.5	Confident	17 Å²	17	53.5 Å²	53.5	10%	0.103	29%	0.292	C	S	.	.	H	α-helix	trans	-60.2	-48	179.3	176.6	0	0	0	0	110.7	L101 L105 K108 T109 L110 L115 Y116 L117	L101-V113 HydrophobicContact CD2-CG2 4.29Å; L105-V113 HydrophobicContact CD1-CG1 3.96Å; L105-V113 HydrophobicContact CD1-CG2 4.15Å; K108-V113 HydrophobicContact CB-CG2 4.17Å; T109-V113 PolarHBondContact O-N 2.85Å; T109-V113 VanDerWaalsContact O-N 3.16Å; L110-V113 PolarHBondContact O-N 3.27Å; V113-L115 PolarHBondContact O-N 2.82Å; V113-Y116 PolarHBondContact O-N 3.37Å; V113-L117 HydrophobicContact CG1-CD1 3.81Å; V113-L117 HydrophobicContact CG1-CG 4.3Å; V113-L117 WeakPolarHBondContact O-CB 3.35Å; V113-L117 WeakPolarHBondContact O-CG 3.44Å; V113-L117 PolarHBondContact O-N 3.34Å
114	V	85.2	Confident	80.9	Confident	43 Å²	43	51 Å²	51	26%	0.261	27%	0.274	S	S	.	.	H	α-helix	trans	-58.8	-45.3	179.3	169	0	0	0	0	111.8	L110 T112 N118 V195 C198	L110-V114 VanDerWaalsContact O-CG2 3.3Å; L110-V114 WeakPolarHBondContact O-CG2 3.31Å; L110-V114 PolarHBondContact O-N 3.12Å; T112-V114 PolarHBondContact O-N 3.46Å; V114-N118 WeakPolarHBondContact O-CB 3.4Å; V114-N118 PolarHBondContact O-N 3.01Å; V114-V195 HydrophobicContact CG1-CG2 4.23Å; V114-V195 HydrophobicContact CG2-CG2 4.34Å; V114-C198 HydrophobicContact CG1-CB 4.48Å
115	L	82.4	Confident	81.9	Confident	19 Å²	19	46.2 Å²	46.2	10%	0.099	26%	0.259	C	S	.	.	H	α-helix	trans	-67.1	-39.4	-179	-71.6	168.9	0	0	0	112.8	S111 T112 V113 N118 L119 K174 A194 M197	S111-L115 WeakPolarHBondContact O-CG 3.3Å; S111-L115 PolarHBondContact O-N 2.79Å; T112-L115 PolarHBondContact O-N 3.44Å; V113-L115 PolarHBondContact O-N 2.82Å; L115-N118 WeakPolarHBondContact O-CB 3.29Å; L115-N118 PolarHBondContact O-N 2.66Å; L115-L119 PolarHBondContact O-N 3.28Å; L115-K174 HydrophobicContact CD1-CD 4.08Å; L115-A194 HydrophobicContact CD1-CB 4.13Å; L115-A194 HydrophobicContact CD2-CB 4.34Å; L115-A194 HydrophobicContact CG-CB 3.95Å; L115-M197 HydrophobicContact CD1-CE 4.33Å; L115-M197 HydrophobicContact CD2-CE 4.11Å
116	Y	85	Confident	83	Confident	12 Å²	12	41.6 Å²	41.6	5%	0.047	24%	0.235	C	C	.	.	H	α-helix	trans	-74.6	-35	179.8	-69.4	-0.1	0	0	0	112.1	L101 T112 V113 N118 L119 A120 C342 L345 S346	L101-Y116 HydrophobicContact CD2-CD2 3.78Å; L101-Y116 HydrophobicContact CD2-CG 4.38Å; L101-Y116 HydrophobicContact CG-CD2 4.32Å; T112-Y116 HydrophobicContact CG2-CD1 4.49Å; T112-Y116 HydrophobicContact CG2-CD2 4.01Å; T112-Y116 HydrophobicContact CG2-CE1 4.13Å; T112-Y116 HydrophobicContact CG2-CE2 3.64Å; T112-Y116 HydrophobicContact CG2-CG 4.42Å; T112-Y116 PolarHBondContact O-N 2.77Å; T112-Y116 VanDerWaalsContact O-N 3.07Å; V113-Y116 PolarHBondContact O-N 3.37Å; Y116-N118 VanDerWaalsContact C-N 3.33Å; Y116-L119 PolarHBondContact O-N 3.38Å; Y116-A120 WeakPolarHBondContact O-CB 3.35Å; Y116-A120 PolarHBondContact O-N 2.86Å; Y116-C342 HydrophobicContact CE1-CB 4.31Å; Y116-C342 HydrophobicContact CE2-CB 4.17Å; Y116-C342 PolarHBondContact OH-O 3.09Å; Y116-L345 HydrophobicContact CE1-CB 4.5Å; Y116-L345 HydrophobicContact CE1-CD1 4.2Å; Y116-L345 WeakPolarHBondContact OH-CB 3.21Å; Y116-S346 PolarHBondContact OH-N 2.7Å
117	L	86.8	Confident	84.5	Confident	84 Å²	84	34.9 Å²	34.9	44%	0.44	19%	0.193	S	C	.	.	H	α-helix	trans	-63	-41.5	171	-74.2	174.4	0	0	0	111.4	L98 L101 V113 L121	L98-L117 HydrophobicContact CD2-CD2 3.84Å; L101-L117 HydrophobicContact CD1-CD2 3.96Å; L101-L117 HydrophobicContact CD1-CG 4.05Å; V113-L117 HydrophobicContact CG1-CD1 3.81Å; V113-L117 HydrophobicContact CG1-CG 4.3Å; V113-L117 WeakPolarHBondContact O-CB 3.35Å; V113-L117 WeakPolarHBondContact O-CG 3.44Å; V113-L117 PolarHBondContact O-N 3.34Å; L117-L121 VanDerWaalsContact O-CB 3.24Å; L117-L121 WeakPolarHBondContact O-CB 3.46Å; L117-L121 PolarHBondContact O-N 3.28Å
118	N	88.1	Confident	85.8	Confident	9 Å²	9	35.8 Å²	35.8	5%	0.048	19%	0.192	C	C	.	.	H	α-helix	trans	-58.3	-49.6	175.1	-177.7	87.9	0	0	0	111.8	V114 L115 Y116 L121 S122 W202	V114-N118 WeakPolarHBondContact O-CB 3.4Å; V114-N118 PolarHBondContact O-N 3.01Å; L115-N118 WeakPolarHBondContact O-CB 3.29Å; L115-N118 PolarHBondContact O-N 2.66Å; Y116-N118 VanDerWaalsContact C-N 3.33Å; N118-L121 PolarHBondContact O-N 3.17Å; N118-S122 PolarHBondContact O-N 3.23Å; N118-S122 PolarHBondContact O-OG 3.48Å; N118-W202 VanDerWaalsContact OD1-CD1 3.28Å; N118-W202 PolarHBondContact OD1-NE1 2.93Å
119	L	87.4	Confident	86.9	Confident	5 Å²	5	33.8 Å²	33.8	3%	0.026	18%	0.183	C	C	.	.	H	α-helix	trans	-62.2	-47.8	179.9	-171.5	63.5	0	0	0	111.8	L115 Y116 L121 S122 D123 T167 D338	L115-L119 PolarHBondContact O-N 3.28Å; Y116-L119 PolarHBondContact O-N 3.38Å; L119-L121 VanDerWaalsContact C-N 3.32Å; L119-L121 PolarHBondContact O-N 2.87Å; L119-S122 PolarHBondContact O-N 3.08Å; L119-S122 PolarHBondContact O-OG 2.91Å; L119-D123 WeakPolarHBondContact O-CB 3.09Å; L119-D123 PolarHBondContact O-N 3.23Å; L119-T167 HydrophobicContact CD1-CG2 4.22Å; L119-D338 HydrophobicContact CD2-CB 3.82Å; L119-D338 HydrophobicContact CG-CB 4.26Å
120	A	89.7	Confident	87.9	Confident	0 Å²	0	30 Å²	30	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-63.2	-38.7	177.9	0	0	0	0	0	112.3	L98 Y116 L124	L98-A120 HydrophobicContact CD1-CB 4.34Å; L98-A120 HydrophobicContact CD2-CB 3.64Å; L98-A120 HydrophobicContact CG-CB 3.85Å; Y116-A120 WeakPolarHBondContact O-CB 3.35Å; Y116-A120 PolarHBondContact O-N 2.86Å; A120-L124 WeakPolarHBondContact O-CB 3.25Å; A120-L124 WeakPolarHBondContact O-CG 3.2Å; A120-L124 PolarHBondContact O-N 3.47Å
121	L	89.6	Confident	88.6	Confident	91 Å²	91	26.7 Å²	26.7	48%	0.476	15%	0.15	S	C	.	.	H	α-helix	trans	-67.1	-44.5	178.5	-178.2	60	0	0	0	111.8	L117 N118 L119 L125 W202	L117-L121 VanDerWaalsContact O-CB 3.24Å; L117-L121 WeakPolarHBondContact O-CB 3.46Å; L117-L121 PolarHBondContact O-N 3.28Å; N118-L121 PolarHBondContact O-N 3.17Å; L119-L121 VanDerWaalsContact C-N 3.32Å; L119-L121 PolarHBondContact O-N 2.87Å; L121-L125 WeakPolarHBondContact O-CG 3.42Å; L121-L125 PolarHBondContact O-N 3.18Å; L121-W202 HydrophobicContact CD2-CH2 4.01Å; L121-W202 HydrophobicContact CD2-CZ2 3.62Å; L121-W202 HydrophobicContact CG-CH2 4.17Å; L121-W202 HydrophobicContact CG-CZ2 3.97Å
122	S	90.9	Very high	89.3	Confident	0 Å²	0	29.3 Å²	29.3	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-62.2	-43.9	175.9	51.9	0	0	0	0	111.6	N118 L119 L124 L125 L126 N160	N118-S122 PolarHBondContact O-N 3.23Å; N118-S122 PolarHBondContact O-OG 3.48Å; L119-S122 PolarHBondContact O-N 3.08Å; L119-S122 PolarHBondContact O-OG 2.91Å; S122-L124 PolarHBondContact O-N 3.33Å; S122-L125 WeakPolarHBondContact O-CB 3.2Å; S122-L125 PolarHBondContact O-N 3.09Å; S122-L125 VanDerWaalsContact O-N 3.17Å; S122-L126 PolarHBondContact O-N 3.33Å; S122-N160 WeakPolarHBondContact CA-OD1 3.43Å; S122-N160 PolarHBondContact O-OD1 3.42Å
123	D	91.6	Very high	90	Very high	0 Å²	0	28.6 Å²	28.6	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-67.2	-37.4	-178.5	-79.9	12.8	0	0	0	112.9	N94 L119 L125 L126 V127 H334 S335 D338	N94-D123 VanDerWaalsContact CG-CB 3.43Å; N94-D123 VanDerWaalsContact ND2-CB 3.26Å; N94-D123 WeakPolarHBondContact ND2-CB 3.41Å; N94-D123 PolarHBondContact ND2-OD2 2.87Å; N94-D123 WeakPolarHBondContact OD1-CB 3.4Å; N94-D123 PolarHBondContact OD1-OD2 2.86Å; L119-D123 WeakPolarHBondContact O-CB 3.09Å; L119-D123 PolarHBondContact O-N 3.23Å; D123-L125 VanDerWaalsContact C-N 3.3Å; D123-L125 PolarHBondContact O-N 2.91Å; D123-L126 WeakPolarHBondContact O-CB 3.48Å; D123-L126 PolarHBondContact O-N 3.41Å; D123-V127 WeakPolarHBondContact O-CB 3.49Å; D123-V127 WeakPolarHBondContact O-CG2 3.45Å; D123-V127 PolarHBondContact O-N 3.24Å; D123-H334 IonicContact OD1-NE2 3.01Å; D123-S335 WeakPolarHBondContact OD2-CA 3.4Å; D123-S335 WeakPolarHBondContact OD2-CB 3.46Å; D123-D338 VanDerWaalsContact OD2-OD2 3.06Å
124	L	90.2	Very high	90.5	Very high	63 Å²	63	28.5 Å²	28.5	33%	0.33	16%	0.157	S	C	.	.	H	α-helix	trans	-64	-37.6	174.2	-72.6	172.7	0	0	0	111.6	N94 L98 A120 S122 L126 V127 L128	N94-L124 HydrophobicContact CB-CD2 4.48Å; L98-L124 HydrophobicContact CD1-CD1 3.99Å; A120-L124 WeakPolarHBondContact O-CB 3.25Å; A120-L124 WeakPolarHBondContact O-CG 3.2Å; A120-L124 PolarHBondContact O-N 3.47Å; S122-L124 PolarHBondContact O-N 3.33Å; L124-L126 VanDerWaalsContact C-N 3.35Å; L124-V127 PolarHBondContact O-N 2.89Å; L124-L128 WeakPolarHBondContact O-CB 3.13Å; L124-L128 PolarHBondContact O-N 2.9Å
125	L	92	Very high	91	Very high	40 Å²	40	29.8 Å²	29.8	21%	0.209	16%	0.16	C	C	.	.	H	α-helix	trans	-65.6	-37.9	172.8	-68	173.2	0	0	0	111.8	L121 S122 D123 S129 N160 W202	L121-L125 WeakPolarHBondContact O-CG 3.42Å; L121-L125 PolarHBondContact O-N 3.18Å; S122-L125 WeakPolarHBondContact O-CB 3.2Å; S122-L125 PolarHBondContact O-N 3.09Å; S122-L125 VanDerWaalsContact O-N 3.17Å; D123-L125 VanDerWaalsContact C-N 3.3Å; D123-L125 PolarHBondContact O-N 2.91Å; L125-S129 WeakPolarHBondContact O-CB 3.29Å; L125-S129 PolarHBondContact O-N 3.39Å; L125-S129 PolarHBondContact O-OG 3.02Å; L125-N160 VanDerWaalsContact CB-ND2 3.28Å; L125-N160 WeakPolarHBondContact CB-ND2 3.36Å; L125-W202 HydrophobicContact CD1-CH2 3.81Å; L125-W202 HydrophobicContact CD1-CZ3 4.34Å
126	L	92.9	Very high	91.5	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-62.3	-52.6	174.2	175.8	63.1	0	0	0	110.7	S122 D123 L124 L128 S129 L130 F157 N160	S122-L126 PolarHBondContact O-N 3.33Å; D123-L126 WeakPolarHBondContact O-CB 3.48Å; D123-L126 PolarHBondContact O-N 3.41Å; L124-L126 VanDerWaalsContact C-N 3.35Å; L126-L128 VanDerWaalsContact C-N 3.31Å; L126-L128 PolarHBondContact O-N 2.86Å; L126-S129 CarbonylContact O-C 3.49Å; L126-S129 WeakPolarHBondContact O-CA 3.49Å; L126-S129 WeakPolarHBondContact O-CB 3.46Å; L126-S129 PolarHBondContact O-N 3.29Å; L126-L130 HydrophobicContact CD1-CD1 4.37Å; L126-L130 HydrophobicContact CD1-CG 4.21Å; L126-L130 HydrophobicContact CG-CD1 4.06Å; L126-L130 HydrophobicContact CG-CG 4.31Å; L126-L130 WeakPolarHBondContact O-CG 3.27Å; L126-L130 PolarHBondContact O-N 3.35Å; L126-F157 HydrophobicContact CD1-CD2 4.04Å; L126-F157 HydrophobicContact CD1-CE2 4.17Å; L126-N160 HydrophobicContact CB-CB 3.96Å; L126-N160 HydrophobicContact CD1-CB 4.23Å; L126-N160 PolarHBondContact N-ND2 3.37Å
127	V	93.1	Very high	91.8	Very high	9 Å²	9	28.6 Å²	28.6	6%	0.055	15%	0.154	C	C	.	.	H	α-helix	trans	-58.1	-42.8	179.6	167.1	0	0	0	0	111.5	I87 I91 D123 L124 S129 L130 A131	I87-V127 HydrophobicContact CG1-CG1 4.21Å; I87-V127 HydrophobicContact CG2-CG1 4.25Å; I91-V127 HydrophobicContact CD1-CG1 3.71Å; I91-V127 HydrophobicContact CG1-CG1 3.42Å; I91-V127 VanDerWaalsContact CG1-CG1 3.42Å; I91-V127 HydrophobicContact CG1-CG2 4.5Å; D123-V127 WeakPolarHBondContact O-CB 3.49Å; D123-V127 WeakPolarHBondContact O-CG2 3.45Å; D123-V127 PolarHBondContact O-N 3.24Å; L124-V127 PolarHBondContact O-N 2.89Å; V127-S129 VanDerWaalsContact C-N 3.31Å; V127-S129 PolarHBondContact O-N 3Å; V127-L130 WeakPolarHBondContact O-CB 3.26Å; V127-L130 PolarHBondContact O-N 3.19Å; V127-A131 PolarHBondContact O-N 3.47Å
128	L	92.3	Very high	92	Very high	95 Å²	95	29.9 Å²	29.9	50%	0.497	16%	0.161	S	C	.	.	H	α-helix	trans	-59.5	-43.7	175.2	178.1	63.2	0	0	0	111.5	L124 L126 L130 A131	L124-L128 WeakPolarHBondContact O-CB 3.13Å; L124-L128 PolarHBondContact O-N 2.9Å; L126-L128 VanDerWaalsContact C-N 3.31Å; L126-L128 PolarHBondContact O-N 2.86Å; L128-L130 VanDerWaalsContact C-N 3.35Å; L128-A131 PolarHBondContact O-N 3.12Å
129	S	93.6	Very high	92.1	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-65.5	-39.2	177.1	-52	0	0	0	0	111.8	L125 L126 V127 R133 L156	L125-S129 WeakPolarHBondContact O-CB 3.29Å; L125-S129 PolarHBondContact O-N 3.39Å; L125-S129 PolarHBondContact O-OG 3.02Å; L126-S129 CarbonylContact O-C 3.49Å; L126-S129 WeakPolarHBondContact O-CA 3.49Å; L126-S129 WeakPolarHBondContact O-CB 3.46Å; L126-S129 PolarHBondContact O-N 3.29Å; V127-S129 VanDerWaalsContact C-N 3.31Å; V127-S129 PolarHBondContact O-N 3Å; S129-R133 WeakPolarHBondContact O-CG 3.46Å; S129-R133 PolarHBondContact O-N 3.13Å; S129-L156 WeakPolarHBondContact OG-CB 3.47Å
130	L	94.3	Very high	92	Very high	0 Å²	0	33.3 Å²	33.3	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-63.8	-41.3	176.7	-72.1	177.8	0	0	0	111.8	Y83 T86 I87 L126 V127 L128 L132 R133 V134 F157	Y83-L130 HydrophobicContact CD1-CD2 3.54Å; Y83-L130 HydrophobicContact CD2-CD2 3.94Å; Y83-L130 HydrophobicContact CE1-CD2 3.84Å; Y83-L130 HydrophobicContact CE2-CD2 4.21Å; Y83-L130 HydrophobicContact CG-CD2 3.6Å; T86-L130 HydrophobicContact CG2-CD1 3.6Å; I87-L130 HydrophobicContact CD1-CB 3.91Å; I87-L130 HydrophobicContact CG1-CB 3.93Å; I87-L130 HydrophobicContact CG1-CD1 4.46Å; L126-L130 HydrophobicContact CD1-CD1 4.37Å; L126-L130 HydrophobicContact CD1-CG 4.21Å; L126-L130 HydrophobicContact CG-CD1 4.06Å; L126-L130 HydrophobicContact CG-CG 4.31Å; L126-L130 WeakPolarHBondContact O-CG 3.27Å; L126-L130 PolarHBondContact O-N 3.35Å; V127-L130 WeakPolarHBondContact O-CB 3.26Å; V127-L130 PolarHBondContact O-N 3.19Å; L128-L130 VanDerWaalsContact C-N 3.35Å; L130-L132 VanDerWaalsContact C-N 3.32Å; L130-L132 PolarHBondContact O-N 3.37Å; L130-R133 CarbonylContact O-C 3.53Å; L130-R133 PolarHBondContact O-N 3.15Å; L130-R133 VanDerWaalsContact O-N 3.11Å; L130-V134 WeakPolarHBondContact O-CG2 3.46Å; L130-V134 PolarHBondContact O-N 3.02Å; L130-F157 HydrophobicContact CD2-CD2 4.1Å; L130-F157 HydrophobicContact CD2-CE2 3.63Å
131	A	94.1	Very high	91.9	Very high	47 Å²	47	33.3 Å²	33.3	39%	0.388	19%	0.192	S	C	.	.	H	α-helix	trans	-58.3	-44.6	-179	0	0	0	0	0	112.1	I87 V127 L128 V134 H135	I87-A131 HydrophobicContact CD1-CB 4.21Å; V127-A131 PolarHBondContact O-N 3.47Å; L128-A131 PolarHBondContact O-N 3.12Å; A131-V134 PolarHBondContact O-N 3.02Å; A131-H135 PolarHBondContact O-N 3.11Å
132	L	93.8	Very high	91.9	Very high	54 Å²	54	31.1 Å²	31.1	28%	0.283	18%	0.181	S	C	.	.	H	α-helix	trans	-71.7	-31.5	177.3	-71.2	167	0	0	0	112.5	L130 H135 Y136 W143 F145 I153	L130-L132 VanDerWaalsContact C-N 3.32Å; L130-L132 PolarHBondContact O-N 3.37Å; L132-H135 PolarHBondContact O-N 3.14Å; L132-Y136 PolarHBondContact O-N 3.26Å; L132-Y136 VanDerWaalsContact O-N 3.09Å; L132-W143 HydrophobicContact CB-CH2 4.19Å; L132-F145 HydrophobicContact CD2-CE2 4.13Å; L132-F145 HydrophobicContact CD2-CZ 4.33Å; L132-I153 HydrophobicContact CB-CD1 4.47Å; L132-I153 HydrophobicContact CB-CG1 4.23Å; L132-I153 HydrophobicContact CB-CG2 4.28Å; L132-I153 HydrophobicContact CD1-CD1 3.31Å; L132-I153 HydrophobicContact CD1-CG1 3.63Å; L132-I153 HydrophobicContact CG-CD1 4.48Å
133	R	93.3	Very high	91.9	Very high	12 Å²	12	31.6 Å²	31.6	5%	0.045	18%	0.182	C	C	.	.	H	α-helix	trans	-69.9	-34.5	172.6	-76.2	-176	166.1	-148.5	-2.8	113.2	Y83 S129 L130 Y136 H137 I153 F157	Y83-R133 HydrophobicContact CD2-CB 4.13Å; Y83-R133 HydrophobicContact CE2-CB 4.04Å; S129-R133 WeakPolarHBondContact O-CG 3.46Å; S129-R133 PolarHBondContact O-N 3.13Å; L130-R133 CarbonylContact O-C 3.53Å; L130-R133 PolarHBondContact O-N 3.15Å; L130-R133 VanDerWaalsContact O-N 3.11Å; R133-Y136 WeakPolarHBondContact O-CB 3.34Å; R133-Y136 PolarHBondContact O-N 3.36Å; R133-H137 PolarHBondContact O-CD2 3.42Å; R133-H137 PolarHBondContact O-N 3.39Å; R133-I153 HydrophobicContact CG-CG2 4.04Å; R133-F157 VanDerWaalsContact NH1-CG 3.32Å
134	V	94.9	Very high	92	Very high	15 Å²	15	36.6 Å²	36.6	9%	0.091	21%	0.208	C	C	.	.	H	α-helix	trans	-60.5	-48.5	172.2	167.9	0	0	0	0	109.7	Y83 I84 I87 L130 A131 Y136 H137 L138	Y83-V134 VanDerWaalsContact CB-CG2 3.45Å; Y83-V134 HydrophobicContact CD2-CG2 4.39Å; Y83-V134 HydrophobicContact CG-CG2 4.46Å; I84-V134 HydrophobicContact CD1-CG1 3.9Å; I84-V134 HydrophobicContact CG1-CB 4.47Å; I84-V134 HydrophobicContact CG1-CG1 3.68Å; I84-V134 HydrophobicContact CG1-CG2 3.89Å; I87-V134 HydrophobicContact CD1-CG2 4.05Å; L130-V134 WeakPolarHBondContact O-CG2 3.46Å; L130-V134 PolarHBondContact O-N 3.02Å; A131-V134 PolarHBondContact O-N 3.02Å; V134-Y136 VanDerWaalsContact C-N 3.28Å; V134-Y136 PolarHBondContact O-N 3.32Å; V134-H137 PolarHBondContact O-N 2.78Å; V134-L138 HydrophobicContact CG1-CD1 3.65Å; V134-L138 HydrophobicContact CG1-CG 4.15Å; V134-L138 WeakPolarHBondContact O-CB 3.48Å; V134-L138 VanDerWaalsContact O-CG 3.31Å; V134-L138 WeakPolarHBondContact O-CG 3.49Å; V134-L138 PolarHBondContact O-N 3.35Å
135	H	94.5	Very high	92	Very high	70 Å²	70	37.9 Å²	37.9	32%	0.324	21%	0.211	S	C	.	.	H	α-helix	trans	-55.1	-45.5	175.2	177.2	-75.7	0	0	0	111.7	A131 L132 L138 S139 F145	A131-H135 PolarHBondContact O-N 3.11Å; L132-H135 PolarHBondContact O-N 3.14Å; H135-L138 PolarHBondContact O-N 3.35Å; H135-S139 PolarHBondContact CE1-OG 2.73Å; H135-S139 VanDerWaalsContact CE1-OG 3.3Å; H135-S139 VanDerWaalsContact O-CB 3.31Å; H135-S139 WeakPolarHBondContact O-CB 3.44Å; H135-S139 PolarHBondContact O-N 3.46Å; H135-S139 PolarHBondContact O-OG 3.44Å; H135-F145 AromaticContact CE1-CE2 3.78Å; H135-F145 AromaticContact CE1-CZ 3.72Å; H135-F145 AromaticContact ND1-CE2 3.44Å; H135-F145 WeakPolarHBondContact ND1-CE2 3.38Å; H135-F145 AromaticContact ND1-CZ 3.75Å
136	Y	93.2	Very high	91.9	Very high	5 Å²	5	37.7 Å²	37.7	2%	0.02	22%	0.219	C	C	.	.	H	α-helix	trans	-56.6	-52.5	177.7	169.8	-107.9	0	0	0	112.9	L132 R133 V134 S139 N141 W143 T228 C229 D231	L132-Y136 PolarHBondContact O-N 3.26Å; L132-Y136 VanDerWaalsContact O-N 3.09Å; R133-Y136 WeakPolarHBondContact O-CB 3.34Å; R133-Y136 PolarHBondContact O-N 3.36Å; V134-Y136 VanDerWaalsContact C-N 3.28Å; V134-Y136 PolarHBondContact O-N 3.32Å; Y136-S139 PolarHBondContact O-N 2.84Å; Y136-N141 HydrophobicContact CE1-CB 4.11Å; Y136-N141 HydrophobicContact CE2-CB 4.28Å; Y136-N141 WeakPolarHBondContact CE2-O 3.45Å; Y136-N141 VanDerWaalsContact CZ-O 3.27Å; Y136-N141 WeakPolarHBondContact O-CA 3.07Å; Y136-N141 PolarHBondContact O-N 3.16Å; Y136-N141 WeakPolarHBondContact OH-CB 3.44Å; Y136-N141 PolarHBondContact OH-O 2.83Å; Y136-W143 HydrophobicContact CD2-CB 3.89Å; Y136-W143 AromaticContact CD2-CE3 3.8Å; Y136-W143 HydrophobicContact CD2-CE3 3.8Å; Y136-W143 HydrophobicContact CE2-CB 3.98Å; Y136-W143 HydrophobicContact CG-CE3 4.05Å; Y136-T228 WeakPolarHBondContact OH-CA 3.35Å; Y136-C229 HydrophobicContact CE2-CB 4.22Å; Y136-C229 PolarHBondContact OH-N 2.99Å; Y136-D231 WeakPolarHBondContact CE1-OD2 3.44Å; Y136-D231 PolarHBondContact OH-OD2 2.89Å
137	H	91.3	Very high	91.7	Very high	2 Å²	2	39.5 Å²	39.5	1%	0.009	23%	0.228	C	C	.	.	H	α-helix	trans	-67.5	-38.4	-178.1	-73	-61.4	0	0	0	112.2	S75 P80 R133 V134 S139 G140 N141 D231 R325	S75-H137 PolarHBondContact O-ND1 2.93Å; S75-H137 PolarHBondContact OG-ND1 3.37Å; P80-H137 HydrophobicContact CB-CB 3.94Å; P80-H137 HydrophobicContact CG-CB 3.88Å; R133-H137 PolarHBondContact O-CD2 3.42Å; R133-H137 PolarHBondContact O-N 3.39Å; V134-H137 PolarHBondContact O-N 2.78Å; H137-S139 VanDerWaalsContact C-N 3.28Å; H137-S139 PolarHBondContact O-N 3.09Å; H137-G140 PolarHBondContact O-N 3.11Å; H137-N141 PolarHBondContact ND1-OD1 3.07Å; H137-D231 IonicContact CE1-OD2 3.54Å; H137-R325 PolarHBondContact NE2-NH2 3.12Å
138	L	91.2	Very high	91.6	Very high	110 Å²	110	46 Å²	46	58%	0.576	26%	0.261	S	S	*	.	H	α-helix	trans	-69.3	-24.7	175.5	-66.8	-179.8	0	0	0	113.2	P80 V134 H135 G140	P80-L138 HydrophobicContact CB-CD2 4.11Å; P80-L138 HydrophobicContact CB-CG 4.32Å; P80-L138 HydrophobicContact CG-CD2 4.38Å; V134-L138 HydrophobicContact CG1-CD1 3.65Å; V134-L138 HydrophobicContact CG1-CG 4.15Å; V134-L138 WeakPolarHBondContact O-CB 3.48Å; V134-L138 VanDerWaalsContact O-CG 3.31Å; V134-L138 WeakPolarHBondContact O-CG 3.49Å; V134-L138 PolarHBondContact O-N 3.35Å; H135-L138 PolarHBondContact O-N 3.35Å; L138-G140 PolarHBondContact O-N 3.33Å
139	S	89.9	Confident	91.6	Very high	50 Å²	50	42.9 Å²	42.9	35%	0.35	25%	0.247	S	C	.	.	T	Hydrogen-bonded Turn	trans	-83.1	21.7	173.8	-54.7	0	0	0	0	112.7	H135 Y136 H137 N142	H135-S139 PolarHBondContact CE1-OG 2.73Å; H135-S139 VanDerWaalsContact CE1-OG 3.3Å; H135-S139 VanDerWaalsContact O-CB 3.31Å; H135-S139 WeakPolarHBondContact O-CB 3.44Å; H135-S139 PolarHBondContact O-N 3.46Å; H135-S139 PolarHBondContact O-OG 3.44Å; Y136-S139 PolarHBondContact O-N 2.84Å; H137-S139 VanDerWaalsContact C-N 3.28Å; H137-S139 PolarHBondContact O-N 3.09Å; S139-N142 WeakPolarHBondContact O-CB 3.4Å; S139-N142 PolarHBondContact O-N 2.65Å
140	G	86.1	Confident	91.6	Very high	37 Å²	37	42.9 Å²	42.9	38%	0.381	25%	0.247	S	C	.	.	T	Hydrogen-bonded Turn	trans	67.9	36.2	-178.4	0	0	0	0	0	113.2	H137 L138 N142	H137-G140 PolarHBondContact O-N 3.11Å; L138-G140 PolarHBondContact O-N 3.33Å; G140-N142 PolarHBondContact O-N 3.12Å
141	N	87.4	Confident	91.4	Very high	0 Å²	0	46 Å²	46	0%	0	26%	0.258	C	S	.	.	S	Bend	trans	61.8	31.3	-177.4	-59.6	-48.4	0	0	0	113.7	T70 S75 Y136 H137 I226	T70-N141 PolarHBondContact O-ND2 3.38Å; S75-N141 PolarHBondContact OG-ND2 3Å; S75-N141 PolarHBondContact OG-OD1 3.46Å; S75-N141 VanDerWaalsContact OG-OD1 3.13Å; Y136-N141 HydrophobicContact CE1-CB 4.11Å; Y136-N141 HydrophobicContact CE2-CB 4.28Å; Y136-N141 WeakPolarHBondContact CE2-O 3.45Å; Y136-N141 VanDerWaalsContact CZ-O 3.27Å; Y136-N141 WeakPolarHBondContact O-CA 3.07Å; Y136-N141 PolarHBondContact O-N 3.16Å; Y136-N141 WeakPolarHBondContact OH-CB 3.44Å; Y136-N141 PolarHBondContact OH-O 2.83Å; H137-N141 PolarHBondContact ND1-OD1 3.07Å; N141-I226 HydrophobicContact CB-CD1 4.45Å
142	N	89.3	Confident	91.4	Very high	44 Å²	44	47.8 Å²	47.8	24%	0.235	26%	0.261	C	S	.	.			trans	-104	121.3	174.9	-170.1	23.8	0	0	0	111.9	S139 G140 I226 T227	S139-N142 WeakPolarHBondContact O-CB 3.4Å; S139-N142 PolarHBondContact O-N 2.65Å; G140-N142 PolarHBondContact O-N 3.12Å; N142-I226 HydrophobicContact CB-CB 4.13Å; N142-I226 HydrophobicContact CB-CG2 3.99Å; N142-T227 PolarHBondContact OD1-N 2.94Å
143	W	91.7	Very high	91.4	Very high	10 Å²	10	45.6 Å²	45.6	4%	0.038	25%	0.25	C	C	.	.			trans	-98.6	108.8	-179.3	-172.8	-95.7	0	0	0	111.7	L132 Y136 F145 G146 S149 C150 I153 T227 C229	L132-W143 HydrophobicContact CB-CH2 4.19Å; Y136-W143 HydrophobicContact CD2-CB 3.89Å; Y136-W143 AromaticContact CD2-CE3 3.8Å; Y136-W143 HydrophobicContact CD2-CE3 3.8Å; Y136-W143 HydrophobicContact CE2-CB 3.98Å; Y136-W143 HydrophobicContact CG-CE3 4.05Å; W143-F145 HydrophobicContact CD2-CD2 4.3Å; W143-F145 HydrophobicContact CE3-CD2 4.35Å; W143-F145 AromaticContact CH2-CD2 3.92Å; W143-F145 HydrophobicContact CH2-CD2 3.92Å; W143-F145 HydrophobicContact CZ2-CB 3.86Å; W143-F145 AromaticContact CZ2-CD2 3.85Å; W143-F145 HydrophobicContact CZ2-CD2 3.85Å; W143-F145 HydrophobicContact CZ2-CG 4.32Å; W143-F145 HydrophobicContact CZ3-CD2 4.16Å; W143-G146 PolarHBondContact NE1-O 3.44Å; W143-S149 WeakPolarHBondContact CZ2-OG 3.05Å; W143-S149 PolarHBondContact NE1-OG 3.45Å; W143-C150 HydrophobicContact CD2-CB 4.41Å; W143-C150 HydrophobicContact CG-CB 4.42Å; W143-C150 HydrophobicContact CZ2-CB 4.39Å; W143-I153 HydrophobicContact CH2-CB 4.24Å; W143-I153 HydrophobicContact CH2-CG1 4.07Å; W143-I153 HydrophobicContact CH2-CG2 4.4Å; W143-I153 HydrophobicContact CZ2-CG1 4.46Å; W143-T227 HydrophobicContact CB-CG2 4.45Å; W143-T227 VanDerWaalsContact CB-O 3.29Å; W143-T227 WeakPolarHBondContact CB-O 3.16Å; W143-T227 PolarHBondContact N-O 3.32Å; W143-C229 HydrophobicContact CB-CB 3.83Å; W143-C229 HydrophobicContact CD2-CB 3.88Å; W143-C229 HydrophobicContact CE3-CB 4.04Å; W143-C229 HydrophobicContact CG-CB 3.78Å
144	I	92.3	Very high	91.3	Very high	106 Å²	106	45.1 Å²	45.1	54%	0.544	25%	0.248	S	C	.	.			trans	-98.1	-10.3	-175	63.3	169.8	0	0	0	114.5	G146	I144-G146 VanDerWaalsContact C-N 3.27Å; I144-G146 PolarHBondContact O-N 3.33Å
145	F	90.6	Very high	91.1	Very high	89 Å²	89	44.4 Å²	44.4	39%	0.39	24%	0.244	S	C	.	.	S	Bend	trans	-85.9	5.4	-171.9	-55.8	-71.2	0	0	0	113.9	L132 H135 W143 S149	L132-F145 HydrophobicContact CD2-CE2 4.13Å; L132-F145 HydrophobicContact CD2-CZ 4.33Å; H135-F145 AromaticContact CE1-CE2 3.78Å; H135-F145 AromaticContact CE1-CZ 3.72Å; H135-F145 AromaticContact ND1-CE2 3.44Å; H135-F145 WeakPolarHBondContact ND1-CE2 3.38Å; H135-F145 AromaticContact ND1-CZ 3.75Å; W143-F145 HydrophobicContact CD2-CD2 4.3Å; W143-F145 HydrophobicContact CE3-CD2 4.35Å; W143-F145 AromaticContact CH2-CD2 3.92Å; W143-F145 HydrophobicContact CH2-CD2 3.92Å; W143-F145 HydrophobicContact CZ2-CB 3.86Å; W143-F145 AromaticContact CZ2-CD2 3.85Å; W143-F145 HydrophobicContact CZ2-CD2 3.85Å; W143-F145 HydrophobicContact CZ2-CG 4.32Å; W143-F145 HydrophobicContact CZ3-CD2 4.16Å; F145-S149 WeakPolarHBondContact CB-OG 3.23Å; F145-S149 PolarHBondContact O-OG 3.34Å
146	G	90.3	Very high	91	Very high	37 Å²	37	42.2 Å²	42.2	38%	0.381	23%	0.234	S	C	.	.	H	α-helix	trans	80.3	173.5	180	0	0	0	0	0	115.1	W143 I144 S149 C150	W143-G146 PolarHBondContact NE1-O 3.44Å; I144-G146 VanDerWaalsContact C-N 3.27Å; I144-G146 PolarHBondContact O-N 3.33Å; G146-S149 PolarHBondContact O-OG 2.81Å; G146-C150 PolarHBondContact O-N 2.93Å
147	E	88.3	Confident	91	Very high	37 Å²	37	42 Å²	42	17%	0.173	23%	0.234	C	C	.	.	H	α-helix	trans	-66.5	-41.2	-171.3	171.2	58.7	-172.7	0	0	113.7	S149 C150 R151 K216 Q217 S218	E147-S149 VanDerWaalsContact C-N 3.33Å; E147-S149 PolarHBondContact O-N 3.41Å; E147-C150 WeakPolarHBondContact O-CB 3.42Å; E147-C150 PolarHBondContact O-N 3.47Å; E147-R151 WeakPolarHBondContact O-CG 3.49Å; E147-R151 PolarHBondContact O-N 3.02Å; E147-R151 WeakPolarHBondContact OE1-CG 3.22Å; E147-R151 IonicContact OE1-CZ 3.42Å; E147-R151 IonicContact OE1-NE 2.7Å; E147-R151 PolarHBondContact OE1-NE 3.48Å; E147-R151 IonicContact OE1-NH2 3.25Å; E147-R151 PolarHBondContact OE1-NH2 3.39Å; E147-K216 WeakPolarHBondContact OE1-CA 3.44Å; E147-K216 VanDerWaalsContact OE1-CG 3.26Å; E147-K216 WeakPolarHBondContact OE1-CG 3.28Å; E147-Q217 PolarHBondContact OE1-N 3.32Å; E147-S218 WeakPolarHBondContact OE2-CA 3.46Å; E147-S218 WeakPolarHBondContact OE2-CB 3.22Å; E147-S218 PolarHBondContact OE2-N 3.37Å; E147-S218 PolarHBondContact OE2-OG 3.33Å
148	I	91.3	Very high	90.8	Very high	147 Å²	147	42.2 Å²	42.2	75%	0.754	24%	0.235	S	C	*	.	H	α-helix	trans	-61.7	-44	-176.2	-62.8	173.8	0	0	0	110.7	R151 L152	I148-R151 PolarHBondContact O-N 3.4Å; I148-L152 PolarHBondContact O-N 2.93Å
149	S	92.8	Very high	90.7	Very high	28 Å²	28	37 Å²	37	20%	0.196	21%	0.207	C	C	.	.	H	α-helix	trans	-68.9	-37.5	177.8	61.4	0	0	0	0	111.4	W143 F145 G146 E147 R151 L152 I153	W143-S149 WeakPolarHBondContact CZ2-OG 3.05Å; W143-S149 PolarHBondContact NE1-OG 3.45Å; F145-S149 WeakPolarHBondContact CB-OG 3.23Å; F145-S149 PolarHBondContact O-OG 3.34Å; G146-S149 PolarHBondContact O-OG 2.81Å; E147-S149 VanDerWaalsContact C-N 3.33Å; E147-S149 PolarHBondContact O-N 3.41Å; S149-R151 VanDerWaalsContact C-N 3.34Å; S149-R151 PolarHBondContact O-N 2.95Å; S149-L152 PolarHBondContact O-N 3.2Å; S149-I153 WeakPolarHBondContact O-CB 3.25Å; S149-I153 WeakPolarHBondContact O-CG1 3.41Å; S149-I153 PolarHBondContact O-N 3.38Å
150	C	92.1	Very high	90.8	Very high	0 Å²	0	34.6 Å²	34.6	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-58.7	-45.8	174.6	175.2	0	0	0	0	111.4	W143 G146 E147 T154 Q217 C229	W143-C150 HydrophobicContact CD2-CB 4.41Å; W143-C150 HydrophobicContact CG-CB 4.42Å; W143-C150 HydrophobicContact CZ2-CB 4.39Å; G146-C150 PolarHBondContact O-N 2.93Å; E147-C150 WeakPolarHBondContact O-CB 3.42Å; E147-C150 PolarHBondContact O-N 3.47Å; C150-T154 WeakPolarHBondContact O-CB 3.07Å; C150-T154 PolarHBondContact O-N 3.06Å; C150-T154 PolarHBondContact O-OG1 2.85Å; C150-Q217 WeakPolarHBondContact SG-CB 3.48Å; C150-C229 WeakPolarHBondContact CA-SG 3.44Å; C150-C229 HydrophobicContact CB-CB 4.01Å; C150-C229 WeakPolarHBondContact CB-SG 3.23Å; C150-C229 WeakPolarHBondContact SG-CA 3.39Å; C150-C229 WeakPolarHBondContact SG-CB 3.48Å; C150-C229 CovalentContact SG-SG 2.03Å; C150-C229 PolarHBondContact SG-SG 3.4Å
151	R	91.5	Very high	90.9	Very high	65 Å²	65	33 Å²	33	25%	0.245	17%	0.173	C	C	.	.	H	α-helix	trans	-60.9	-49	175.1	-65.9	-172.1	-168.1	-162.6	-3.3	112	E147 I148 S149 T154 A155 L213 L214 V215 Q217	E147-R151 WeakPolarHBondContact O-CG 3.49Å; E147-R151 PolarHBondContact O-N 3.02Å; E147-R151 WeakPolarHBondContact OE1-CG 3.22Å; E147-R151 IonicContact OE1-CZ 3.42Å; E147-R151 IonicContact OE1-NE 2.7Å; E147-R151 PolarHBondContact OE1-NE 3.48Å; E147-R151 IonicContact OE1-NH2 3.25Å; E147-R151 PolarHBondContact OE1-NH2 3.39Å; I148-R151 PolarHBondContact O-N 3.4Å; S149-R151 VanDerWaalsContact C-N 3.34Å; S149-R151 PolarHBondContact O-N 2.95Å; R151-T154 PolarHBondContact O-N 3.01Å; R151-A155 WeakPolarHBondContact O-CB 3.44Å; R151-A155 PolarHBondContact O-N 2.8Å; R151-L213 HydrophobicContact CB-CD2 4.39Å; R151-L213 VanDerWaalsContact CD-O 3.22Å; R151-L213 WeakPolarHBondContact CD-O 3.37Å; R151-L213 PolarHBondContact NH1-O 3.2Å; R151-L214 PolarHBondContact NH1-O 3.31Å; R151-V215 WeakPolarHBondContact CD-O 3.12Å; R151-V215 PolarHBondContact NE-O 2.99Å; R151-V215 VanDerWaalsContact NE-O 3.12Å; R151-Q217 HydrophobicContact CB-CG 4.47Å; R151-Q217 HydrophobicContact CG-CB 4.19Å; R151-Q217 HydrophobicContact CG-CG 3.87Å
152	L	93.4	Very high	90.9	Very high	85 Å²	85	33.3 Å²	33.3	45%	0.445	17%	0.174	S	C	.	.	H	α-helix	trans	-60.1	-50.6	-178.6	-179.3	62.6	0	0	0	111.5	I148 S149 T154 A155 L156	I148-L152 PolarHBondContact O-N 2.93Å; S149-L152 PolarHBondContact O-N 3.2Å; L152-T154 PolarHBondContact O-N 3.44Å; L152-A155 WeakPolarHBondContact O-CB 3.4Å; L152-A155 PolarHBondContact O-N 3.5Å; L152-L156 HydrophobicContact CD1-CD1 4.19Å; L152-L156 HydrophobicContact CD1-CD2 4.47Å; L152-L156 HydrophobicContact CD1-CG 4.1Å; L152-L156 HydrophobicContact CG-CD1 4.09Å; L152-L156 HydrophobicContact CG-CG 4.36Å; L152-L156 WeakPolarHBondContact O-CB 3.45Å; L152-L156 VanDerWaalsContact O-CG 3.27Å; L152-L156 WeakPolarHBondContact O-CG 3.49Å; L152-L156 PolarHBondContact O-N 2.95Å
153	I	93.2	Very high	90.9	Very high	9 Å²	9	31.2 Å²	31.2	5%	0.046	16%	0.163	C	C	.	.	H	α-helix	trans	-67.6	-37.6	-177.7	-63.8	-49	0	0	0	112	L132 R133 W143 S149 L156 F157	L132-I153 HydrophobicContact CB-CD1 4.47Å; L132-I153 HydrophobicContact CB-CG1 4.23Å; L132-I153 HydrophobicContact CB-CG2 4.28Å; L132-I153 HydrophobicContact CD1-CD1 3.31Å; L132-I153 HydrophobicContact CD1-CG1 3.63Å; L132-I153 HydrophobicContact CG-CD1 4.48Å; R133-I153 HydrophobicContact CG-CG2 4.04Å; W143-I153 HydrophobicContact CH2-CB 4.24Å; W143-I153 HydrophobicContact CH2-CG1 4.07Å; W143-I153 HydrophobicContact CH2-CG2 4.4Å; W143-I153 HydrophobicContact CZ2-CG1 4.46Å; S149-I153 WeakPolarHBondContact O-CB 3.25Å; S149-I153 WeakPolarHBondContact O-CG1 3.41Å; S149-I153 PolarHBondContact O-N 3.38Å; I153-L156 HydrophobicContact CD1-CD1 4.31Å; I153-F157 WeakPolarHBondContact O-CB 3.38Å; I153-F157 PolarHBondContact O-N 3.31Å
154	T	91	Very high	90.9	Very high	1 Å²	1	30.8 Å²	30.8	1%	0.006	16%	0.162	C	C	.	.	H	α-helix	trans	-62.9	-45.2	173.1	-62.2	0	0	0	0	111.2	C150 R151 L152 F157 F158 E212 H230	C150-T154 WeakPolarHBondContact O-CB 3.07Å; C150-T154 PolarHBondContact O-N 3.06Å; C150-T154 PolarHBondContact O-OG1 2.85Å; R151-T154 PolarHBondContact O-N 3.01Å; L152-T154 PolarHBondContact O-N 3.44Å; T154-F157 PolarHBondContact O-N 3.48Å; T154-F158 HydrophobicContact CG2-CD2 3.85Å; T154-F158 HydrophobicContact CG2-CE2 3.94Å; T154-F158 VanDerWaalsContact O-CD2 3.31Å; T154-F158 WeakPolarHBondContact O-CD2 3.07Å; T154-F158 PolarHBondContact O-N 2.94Å; T154-F158 VanDerWaalsContact O-N 3.08Å; T154-E212 HydrophobicContact CG2-CG 4.48Å; T154-H230 HydrophobicContact CG2-CB 3.97Å; T154-H230 VanDerWaalsContact CG2-ND1 3.29Å; T154-H230 WeakPolarHBondContact CG2-ND1 3.24Å
155	A	91.7	Very high	90.8	Very high	1 Å²	1	25.7 Å²	25.7	1%	0.008	14%	0.136	C	C	.	.	H	α-helix	trans	-62.7	-50.8	178.5	0	0	0	0	0	111.9	R151 L152 F157 G159 I209 E212 L213	R151-A155 WeakPolarHBondContact O-CB 3.44Å; R151-A155 PolarHBondContact O-N 2.8Å; L152-A155 WeakPolarHBondContact O-CB 3.4Å; L152-A155 PolarHBondContact O-N 3.5Å; A155-F157 VanDerWaalsContact C-N 3.31Å; A155-F157 PolarHBondContact O-N 2.91Å; A155-G159 WeakPolarHBondContact O-CA 3.42Å; A155-G159 PolarHBondContact O-N 3.28Å; A155-I209 HydrophobicContact CB-CB 4Å; A155-I209 HydrophobicContact CB-CG2 4.3Å; A155-I209 VanDerWaalsContact O-CG2 3.24Å; A155-I209 WeakPolarHBondContact O-CG2 3.48Å; A155-E212 HydrophobicContact CB-CB 3.69Å; A155-E212 HydrophobicContact CB-CG 4.49Å; A155-L213 HydrophobicContact CB-CD2 3.65Å; A155-L213 HydrophobicContact CB-CG 3.76Å
156	L	92.9	Very high	90.9	Very high	24 Å²	24	22.1 Å²	22.1	13%	0.126	12%	0.12	C	C	.	.	H	α-helix	trans	-59.3	-42.5	177.1	-67	178.7	0	0	0	111.2	S129 L152 I153 N160 Y205	S129-L156 WeakPolarHBondContact OG-CB 3.47Å; L152-L156 HydrophobicContact CD1-CD1 4.19Å; L152-L156 HydrophobicContact CD1-CD2 4.47Å; L152-L156 HydrophobicContact CD1-CG 4.1Å; L152-L156 HydrophobicContact CG-CD1 4.09Å; L152-L156 HydrophobicContact CG-CG 4.36Å; L152-L156 WeakPolarHBondContact O-CB 3.45Å; L152-L156 VanDerWaalsContact O-CG 3.27Å; L152-L156 WeakPolarHBondContact O-CG 3.49Å; L152-L156 PolarHBondContact O-N 2.95Å; I153-L156 HydrophobicContact CD1-CD1 4.31Å; L156-N160 WeakPolarHBondContact O-CB 3.31Å; L156-N160 PolarHBondContact O-N 3.36Å; L156-N160 PolarHBondContact O-ND2 3.47Å; L156-Y205 WeakPolarHBondContact CD2-OH 3.35Å
157	F	92.3	Very high	90.8	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-60.8	-56.4	179.7	179.5	-93.3	0	0	0	112.5	L126 L130 R133 I153 T154 A155 N160 V161 V328	L126-F157 HydrophobicContact CD1-CD2 4.04Å; L126-F157 HydrophobicContact CD1-CE2 4.17Å; L130-F157 HydrophobicContact CD2-CD2 4.1Å; L130-F157 HydrophobicContact CD2-CE2 3.63Å; R133-F157 VanDerWaalsContact NH1-CG 3.32Å; I153-F157 WeakPolarHBondContact O-CB 3.38Å; I153-F157 PolarHBondContact O-N 3.31Å; T154-F157 PolarHBondContact O-N 3.48Å; A155-F157 VanDerWaalsContact C-N 3.31Å; A155-F157 PolarHBondContact O-N 2.91Å; F157-N160 PolarHBondContact O-N 3Å; F157-V161 HydrophobicContact CE1-CG2 4.25Å; F157-V161 HydrophobicContact CZ-CG2 4.39Å; F157-V161 WeakPolarHBondContact O-CG2 3.24Å; F157-V161 PolarHBondContact O-N 3.26Å; F157-V328 HydrophobicContact CE1-CG1 3.56Å; F157-V328 HydrophobicContact CZ-CG1 3.34Å
158	F	87.5	Confident	90.8	Very high	7 Å²	7	18.9 Å²	18.9	3%	0.031	10%	0.096	C	C	.	.	H	α-helix	trans	-70.8	-36.8	-178.3	-74.4	-65.1	0	0	0	112.4	T154 N160 V161 Y162 H230 Y324	T154-F158 HydrophobicContact CG2-CD2 3.85Å; T154-F158 HydrophobicContact CG2-CE2 3.94Å; T154-F158 VanDerWaalsContact O-CD2 3.31Å; T154-F158 WeakPolarHBondContact O-CD2 3.07Å; T154-F158 PolarHBondContact O-N 2.94Å; T154-F158 VanDerWaalsContact O-N 3.08Å; F158-N160 VanDerWaalsContact C-N 3.27Å; F158-N160 PolarHBondContact O-N 3.33Å; F158-V161 PolarHBondContact O-N 3.08Å; F158-Y162 HydrophobicContact CB-CE2 4.19Å; F158-Y162 WeakPolarHBondContact O-CD2 3.26Å; F158-Y162 PolarHBondContact O-N 2.93Å; F158-Y162 VanDerWaalsContact O-N 3.12Å; F158-H230 AromaticContact CE2-CD2 3.63Å; F158-H230 AromaticContact CE2-CE1 3.5Å; F158-H230 VanDerWaalsContact CE2-CE1 3.5Å; F158-H230 WeakPolarHBondContact CE2-CE1 3.36Å; F158-H230 AromaticContact CE2-NE2 3.11Å; F158-H230 WeakPolarHBondContact CE2-NE2 3.43Å; F158-H230 AromaticContact CZ-CD2 3.98Å; F158-H230 AromaticContact CZ-NE2 3.35Å; F158-H230 WeakPolarHBondContact CZ-NE2 3.35Å; F158-Y324 WeakPolarHBondContact CE1-OH 3.23Å; F158-Y324 WeakPolarHBondContact CZ-OH 3.44Å
159	G	89.9	Confident	90.9	Very high	0 Å²	0	12.3 Å²	12.3	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-52.7	-48.6	172.2	0	0	0	0	0	111.1	A155 Y162 C163 Y205	A155-G159 WeakPolarHBondContact O-CA 3.42Å; A155-G159 PolarHBondContact O-N 3.28Å; G159-Y162 PolarHBondContact O-N 3.25Å; G159-C163 VanDerWaalsContact O-CB 3.3Å; G159-C163 WeakPolarHBondContact O-CB 3.28Å; G159-C163 PolarHBondContact O-N 3.43Å; G159-Y205 VanDerWaalsContact O-CD2 3.26Å; G159-Y205 WeakPolarHBondContact O-CD2 3.45Å
160	N	90.8	Very high	90.8	Very high	0 Å²	0	12.1 Å²	12.1	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-64.7	-43.6	179.9	-81.8	-57.9	0	0	0	112.6	S122 L125 L126 L156 F157 F158 Y162 C163 S164	S122-N160 WeakPolarHBondContact CA-OD1 3.43Å; S122-N160 PolarHBondContact O-OD1 3.42Å; L125-N160 VanDerWaalsContact CB-ND2 3.28Å; L125-N160 WeakPolarHBondContact CB-ND2 3.36Å; L126-N160 HydrophobicContact CB-CB 3.96Å; L126-N160 HydrophobicContact CD1-CB 4.23Å; L126-N160 PolarHBondContact N-ND2 3.37Å; L156-N160 WeakPolarHBondContact O-CB 3.31Å; L156-N160 PolarHBondContact O-N 3.36Å; L156-N160 PolarHBondContact O-ND2 3.47Å; F157-N160 PolarHBondContact O-N 3Å; F158-N160 VanDerWaalsContact C-N 3.27Å; F158-N160 PolarHBondContact O-N 3.33Å; N160-Y162 VanDerWaalsContact C-N 3.26Å; N160-Y162 PolarHBondContact O-N 2.93Å; N160-C163 PolarHBondContact O-N 3.39Å; N160-C163 VanDerWaalsContact O-N 3.13Å; N160-S164 WeakPolarHBondContact O-CB 3.42Å; N160-S164 PolarHBondContact O-N 3.33Å; N160-S164 PolarHBondContact O-OG 3.19Å; N160-S164 VanDerWaalsContact O-OG 3.08Å
161	V	88.1	Confident	90.6	Very high	3 Å²	3	12.7 Å²	12.7	2%	0.018	6%	0.064	C	C	.	.	H	α-helix	trans	-54.1	-43.8	176.3	169.5	0	0	0	0	111.6	F157 F158 A165 F255	F157-V161 HydrophobicContact CE1-CG2 4.25Å; F157-V161 HydrophobicContact CZ-CG2 4.39Å; F157-V161 WeakPolarHBondContact O-CG2 3.24Å; F157-V161 PolarHBondContact O-N 3.26Å; F158-V161 PolarHBondContact O-N 3.08Å; V161-A165 PolarHBondContact O-N 3.13Å; V161-F255 HydrophobicContact CG1-CE1 4.16Å; V161-F255 HydrophobicContact CG1-CE2 4.18Å; V161-F255 HydrophobicContact CG1-CZ 3.38Å
162	Y	88.4	Confident	90.6	Very high	6 Å²	6	10.2 Å²	10.2	2%	0.024	6%	0.057	C	C	.	.	H	α-helix	trans	-71.2	-42.2	176.1	-62.2	-57	0	0	0	113.1	F158 G159 N160 S164 A165 Q166 A208 F255 H305	F158-Y162 HydrophobicContact CB-CE2 4.19Å; F158-Y162 WeakPolarHBondContact O-CD2 3.26Å; F158-Y162 PolarHBondContact O-N 2.93Å; F158-Y162 VanDerWaalsContact O-N 3.12Å; G159-Y162 PolarHBondContact O-N 3.25Å; N160-Y162 VanDerWaalsContact C-N 3.26Å; N160-Y162 PolarHBondContact O-N 2.93Å; Y162-S164 PolarHBondContact O-N 3.28Å; Y162-A165 PolarHBondContact O-N 3.03Å; Y162-Q166 VanDerWaalsContact O-CG 3.32Å; Y162-Q166 WeakPolarHBondContact O-CG 3.47Å; Y162-Q166 PolarHBondContact O-N 3.45Å; Y162-A208 HydrophobicContact CD2-CB 3.62Å; Y162-A208 HydrophobicContact CE2-CB 4.2Å; Y162-A208 HydrophobicContact CG-CB 4.43Å; Y162-F255 AromaticContact CD1-CD2 3.83Å; Y162-F255 HydrophobicContact CD1-CD2 3.83Å; Y162-F255 AromaticContact CD1-CE2 3.63Å; Y162-F255 HydrophobicContact CD1-CE2 3.63Å; Y162-F255 HydrophobicContact CD1-CZ 4.43Å; Y162-F255 AromaticContact CE1-CD2 3.53Å; Y162-F255 HydrophobicContact CE1-CD2 3.53Å; Y162-F255 AromaticContact CE1-CE2 3.3Å; Y162-F255 HydrophobicContact CE1-CE2 3.3Å; Y162-F255 HydrophobicContact CE1-CZ 4.4Å; Y162-H305 PolarHBondContact OH-CE1 3.46Å
163	C	90	Very high	90.5	Very high	0 Å²	0	9.7 Å²	9.7	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-60.6	-43.3	179.1	174.6	0	0	0	0	112	G159 N160 Q166 T167 V201 Y205	G159-C163 VanDerWaalsContact O-CB 3.3Å; G159-C163 WeakPolarHBondContact O-CB 3.28Å; G159-C163 PolarHBondContact O-N 3.43Å; N160-C163 PolarHBondContact O-N 3.39Å; N160-C163 VanDerWaalsContact O-N 3.13Å; C163-Q166 PolarHBondContact O-N 3.46Å; C163-T167 WeakPolarHBondContact O-CB 3.34Å; C163-T167 PolarHBondContact O-N 3.36Å; C163-T167 PolarHBondContact O-OG1 2.84Å; C163-V201 HydrophobicContact CB-CG1 4.25Å; C163-V201 WeakPolarHBondContact SG-CG1 3.44Å; C163-Y205 HydrophobicContact CB-CD2 3.75Å; C163-Y205 HydrophobicContact CB-CG 4.49Å
164	S	90.6	Very high	90.2	Very high	1 Å²	1	10.7 Å²	10.7	1%	0.007	6%	0.058	C	C	.	.	H	α-helix	trans	-65.5	-43.2	178.1	-59.3	0	0	0	0	111.8	N160 Y162 Q166 T167 I168 H334	N160-S164 WeakPolarHBondContact O-CB 3.42Å; N160-S164 PolarHBondContact O-N 3.33Å; N160-S164 PolarHBondContact O-OG 3.19Å; N160-S164 VanDerWaalsContact O-OG 3.08Å; Y162-S164 PolarHBondContact O-N 3.28Å; S164-Q166 VanDerWaalsContact C-N 3.32Å; S164-Q166 PolarHBondContact O-N 2.91Å; S164-T167 PolarHBondContact O-N 3.03Å; S164-I168 WeakPolarHBondContact O-CG1 3.29Å; S164-I168 PolarHBondContact O-N 3.23Å; S164-H334 WeakPolarHBondContact CB-NE2 3.48Å; S164-H334 PolarHBondContact OG-CE1 3.36Å; S164-H334 PolarHBondContact OG-NE2 3.39Å
165	A	90.9	Very high	90	Very high	0 Å²	0	11.5 Å²	11.5	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-58.8	-44.6	175.8	0	0	0	0	0	111.7	V161 Y162 I168 A169 G254 P258 F294 F298	V161-A165 PolarHBondContact O-N 3.13Å; Y162-A165 PolarHBondContact O-N 3.03Å; A165-I168 PolarHBondContact O-N 2.89Å; A165-A169 PolarHBondContact O-N 2.95Å; A165-A169 VanDerWaalsContact O-N 3.09Å; A165-G254 WeakPolarHBondContact CB-O 3.33Å; A165-P258 HydrophobicContact CB-CB 4.46Å; A165-F294 HydrophobicContact CB-CE2 4.37Å; A165-F298 HydrophobicContact CB-CD1 3.63Å; A165-F298 HydrophobicContact CB-CE1 3.83Å; A165-F298 HydrophobicContact CB-CG 4.44Å
166	Q	91.2	Very high	89.9	Confident	14 Å²	14	12.8 Å²	12.8	7%	0.065	7%	0.066	C	C	.	.	H	α-helix	trans	-69	-39.3	177.6	-68.3	169.6	9	0	0	112.4	Y162 C163 S164 I168 A169 C170 V201 L204 P258	Y162-Q166 VanDerWaalsContact O-CG 3.32Å; Y162-Q166 WeakPolarHBondContact O-CG 3.47Å; Y162-Q166 PolarHBondContact O-N 3.45Å; C163-Q166 PolarHBondContact O-N 3.46Å; S164-Q166 VanDerWaalsContact C-N 3.32Å; S164-Q166 PolarHBondContact O-N 2.91Å; Q166-I168 VanDerWaalsContact C-N 3.32Å; Q166-I168 PolarHBondContact O-N 3.31Å; Q166-A169 PolarHBondContact O-N 3.26Å; Q166-C170 PolarHBondContact O-N 3.16Å; Q166-C170 PolarHBondContact O-SG 3.05Å; Q166-C170 VanDerWaalsContact O-SG 3.38Å; Q166-V201 HydrophobicContact CB-CG2 4.1Å; Q166-L204 VanDerWaalsContact CD-CD1 3.49Å; Q166-L204 HydrophobicContact CG-CD1 4.47Å; Q166-P258 HydrophobicContact CG-CG 3.93Å
167	T	89.3	Confident	89.7	Confident	4 Å²	4	12.7 Å²	12.7	3%	0.025	7%	0.065	C	C	.	.	H	α-helix	trans	-59.8	-44.7	175.8	-62.1	0	0	0	0	110.7	L119 C163 S164 A169 C170 I171	L119-T167 HydrophobicContact CD1-CG2 4.22Å; C163-T167 WeakPolarHBondContact O-CB 3.34Å; C163-T167 PolarHBondContact O-N 3.36Å; C163-T167 PolarHBondContact O-OG1 2.84Å; S164-T167 PolarHBondContact O-N 3.03Å; T167-A169 PolarHBondContact O-N 3.39Å; T167-C170 WeakPolarHBondContact O-CB 3.4Å; T167-C170 PolarHBondContact O-N 2.87Å; T167-I171 HydrophobicContact CG2-CD1 4.19Å; T167-I171 WeakPolarHBondContact O-CG1 3.28Å; T167-I171 PolarHBondContact O-N 3.5Å
168	I	88.8	Confident	89.3	Confident	2 Å²	2	13 Å²	13	1%	0.01	7%	0.068	C	C	.	.	H	α-helix	trans	-62.1	-41.2	175.2	-76.5	168.5	0	0	0	111.8	S164 A165 Q166 I171 S172 V290 I293 F294 F298	S164-I168 WeakPolarHBondContact O-CG1 3.29Å; S164-I168 PolarHBondContact O-N 3.23Å; A165-I168 PolarHBondContact O-N 2.89Å; Q166-I168 VanDerWaalsContact C-N 3.32Å; Q166-I168 PolarHBondContact O-N 3.31Å; I168-I171 PolarHBondContact O-N 3.36Å; I168-S172 PolarHBondContact O-N 3.35Å; I168-S172 PolarHBondContact O-OG 3.37Å; I168-V290 HydrophobicContact CG2-CG1 3.63Å; I168-I293 HydrophobicContact CD1-CG2 3.86Å; I168-F294 HydrophobicContact CG2-CD2 3.91Å; I168-F298 HydrophobicContact CD1-CD2 4.07Å; I168-F298 HydrophobicContact CD1-CE2 3.22Å; I168-F298 HydrophobicContact CD1-CZ 3.61Å
169	A	92.2	Very high	89.2	Confident	9 Å²	9	13.2 Å²	13.2	7%	0.074	7%	0.07	C	C	.	.	H	α-helix	trans	-64.5	-39.5	174.3	0	0	0	0	0	112.3	A165 Q166 T167 S172 L173 P258 V261	A165-A169 PolarHBondContact O-N 2.95Å; A165-A169 VanDerWaalsContact O-N 3.09Å; Q166-A169 PolarHBondContact O-N 3.26Å; T167-A169 PolarHBondContact O-N 3.39Å; A169-S172 PolarHBondContact O-N 2.82Å; A169-L173 WeakPolarHBondContact O-CB 3.49Å; A169-L173 PolarHBondContact O-N 3.05Å; A169-P258 HydrophobicContact CB-CB 3.82Å; A169-V261 HydrophobicContact CB-CB 4.37Å; A169-V261 HydrophobicContact CB-CG1 4.23Å
170	C	91.2	Very high	89.1	Confident	23 Å²	23	14.1 Å²	14.1	16%	0.155	8%	0.075	C	C	.	.	H	α-helix	trans	-62.6	-42.4	173.5	-73.6	0	0	0	0	112	Q166 T167 L173 K174 M197	Q166-C170 PolarHBondContact O-N 3.16Å; Q166-C170 PolarHBondContact O-SG 3.05Å; Q166-C170 VanDerWaalsContact O-SG 3.38Å; T167-C170 WeakPolarHBondContact O-CB 3.4Å; T167-C170 PolarHBondContact O-N 2.87Å; C170-L173 PolarHBondContact O-N 2.98Å; C170-K174 WeakPolarHBondContact O-CB 3.29Å; C170-K174 PolarHBondContact O-N 3.45Å; C170-M197 HydrophobicContact CB-CB 4.17Å; C170-M197 HydrophobicContact CB-CG 4.19Å; C170-M197 HydrophobicContact CB-SD 3.77Å
171	I	88.1	Confident	88.9	Confident	13 Å²	13	19.1 Å²	19.1	7%	0.067	10%	0.097	C	C	.	.	H	α-helix	trans	-59.9	-48.2	173.9	-68.2	168.2	0	0	0	109.6	T167 I168 L173 K174 R175 V290 L341 L345	T167-I171 HydrophobicContact CG2-CD1 4.19Å; T167-I171 WeakPolarHBondContact O-CG1 3.28Å; T167-I171 PolarHBondContact O-N 3.5Å; I168-I171 PolarHBondContact O-N 3.36Å; I171-L173 VanDerWaalsContact C-N 3.35Å; I171-L173 PolarHBondContact O-N 3.44Å; I171-K174 WeakPolarHBondContact O-CB 3.48Å; I171-K174 PolarHBondContact O-N 3.21Å; I171-R175 WeakPolarHBondContact O-CG 3.49Å; I171-R175 PolarHBondContact O-N 3.41Å; I171-V290 HydrophobicContact CG2-CG2 4.41Å; I171-L341 HydrophobicContact CD1-CD2 3.99Å; I171-L345 HydrophobicContact CG2-CD1 4.28Å; I171-L345 HydrophobicContact CG2-CD2 4.32Å
172	S	90.6	Very high	88.6	Confident	13 Å²	13	20.3 Å²	20.3	9%	0.091	11%	0.105	C	C	.	.	H	α-helix	trans	-59.6	-42.8	178.3	-55	0	0	0	0	112.4	I168 A169 R175 Y176 T265 V290	I168-S172 PolarHBondContact O-N 3.35Å; I168-S172 PolarHBondContact O-OG 3.37Å; A169-S172 PolarHBondContact O-N 2.82Å; S172-R175 WeakPolarHBondContact O-CB 3.47Å; S172-R175 PolarHBondContact O-N 3.38Å; S172-Y176 PolarHBondContact O-N 2.85Å; S172-T265 VanDerWaalsContact CB-OG1 3.31Å; S172-T265 WeakPolarHBondContact CB-OG1 3.24Å; S172-V290 WeakPolarHBondContact OG-CG1 3.35Å
173	L	91.8	Very high	88.3	Confident	73 Å²	73	26 Å²	26	38%	0.382	13%	0.13	S	C	.	.	H	α-helix	trans	-65	-43.1	176.3	-177.8	62.7	0	0	0	112.4	A169 C170 I171 R175 Y176 L177 V261 T265	A169-L173 WeakPolarHBondContact O-CB 3.49Å; A169-L173 PolarHBondContact O-N 3.05Å; C170-L173 PolarHBondContact O-N 2.98Å; I171-L173 VanDerWaalsContact C-N 3.35Å; I171-L173 PolarHBondContact O-N 3.44Å; L173-R175 PolarHBondContact O-N 3.16Å; L173-Y176 HydrophobicContact CD1-CD1 4.11Å; L173-Y176 WeakPolarHBondContact O-CB 3.35Å; L173-Y176 PolarHBondContact O-N 3Å; L173-L177 WeakPolarHBondContact O-CG 3.33Å; L173-L177 PolarHBondContact O-N 3.49Å; L173-V261 HydrophobicContact CB-CG1 4.41Å; L173-T265 HydrophobicContact CD1-CG2 4.35Å
174	K	86.8	Confident	88	Confident	30 Å²	30	30.6 Å²	30.6	13%	0.13	15%	0.154	C	C	.	.	H	α-helix	trans	-57.3	-41.1	174.8	-176	-178	178.8	174.9	0	110.8	S111 L115 C170 I171 L177 A178 Y185 M197	S111-K174 PolarHBondContact OG-NZ 2.99Å; S111-K174 VanDerWaalsContact OG-NZ 3.13Å; L115-K174 HydrophobicContact CD1-CD 4.08Å; C170-K174 WeakPolarHBondContact O-CB 3.29Å; C170-K174 PolarHBondContact O-N 3.45Å; I171-K174 WeakPolarHBondContact O-CB 3.48Å; I171-K174 PolarHBondContact O-N 3.21Å; K174-L177 PolarHBondContact O-N 2.68Å; K174-A178 PolarHBondContact O-N 3.08Å; K174-A178 VanDerWaalsContact O-N 3.08Å; K174-Y185 WeakPolarHBondContact CE-OH 3.08Å; K174-Y185 HydrophobicContact CG-CE2 4.13Å; K174-M197 HydrophobicContact CB-CE 4.39Å; K174-M197 HydrophobicContact CD-CE 4.22Å
175	R	86.5	Confident	87.7	Confident	18 Å²	18	31.2 Å²	31.2	7%	0.068	16%	0.156	C	C	.	.	H	α-helix	trans	-67	-43.8	177.1	-64.9	-54.2	-62.7	-162.3	-22.1	112.6	I171 S172 L173 L177 A178 V179 F283 T348	I171-R175 WeakPolarHBondContact O-CG 3.49Å; I171-R175 PolarHBondContact O-N 3.41Å; S172-R175 WeakPolarHBondContact O-CB 3.47Å; S172-R175 PolarHBondContact O-N 3.38Å; L173-R175 PolarHBondContact O-N 3.16Å; R175-L177 VanDerWaalsContact C-N 3.31Å; R175-L177 PolarHBondContact O-N 2.83Å; R175-A178 PolarHBondContact O-N 3.35Å; R175-V179 PolarHBondContact O-N 3.08Å; R175-F283 VanDerWaalsContact CZ-CE1 3.48Å; R175-T348 PolarHBondContact NH1-OG1 3.28Å
176	Y	90.3	Very high	87.2	Confident	28 Å²	28	39.6 Å²	39.6	11%	0.11	19%	0.188	C	C	.	.	H	α-helix	trans	-56	-46.4	172.7	166	-93.9	0	0	0	111.8	S172 L173 A178 V179 V180 K181 Y264 T265 A268	S172-Y176 PolarHBondContact O-N 2.85Å; L173-Y176 HydrophobicContact CD1-CD1 4.11Å; L173-Y176 WeakPolarHBondContact O-CB 3.35Å; L173-Y176 PolarHBondContact O-N 3Å; Y176-A178 VanDerWaalsContact C-N 3.32Å; Y176-A178 PolarHBondContact O-N 3.17Å; Y176-V179 PolarHBondContact O-N 3.05Å; Y176-V180 HydrophobicContact CD2-CB 3.82Å; Y176-V180 HydrophobicContact CD2-CG1 4.32Å; Y176-V180 HydrophobicContact CD2-CG2 3.5Å; Y176-V180 HydrophobicContact CE2-CB 3.62Å; Y176-V180 HydrophobicContact CE2-CG1 3.6Å; Y176-V180 HydrophobicContact CE2-CG2 3.63Å; Y176-V180 HydrophobicContact CG-CB 4.44Å; Y176-V180 HydrophobicContact CG-CG2 4.35Å; Y176-V180 VanDerWaalsContact O-CB 3.31Å; Y176-V180 WeakPolarHBondContact O-CB 3.36Å; Y176-V180 PolarHBondContact O-N 3.46Å; Y176-K181 HydrophobicContact CE1-CG 4.41Å; Y176-Y264 HydrophobicContact CD2-CE1 4.36Å; Y176-Y264 AromaticContact CE2-CE1 3.79Å; Y176-Y264 HydrophobicContact CE2-CE1 3.79Å; Y176-Y264 AromaticContact CZ-CE1 3.93Å; Y176-Y264 PolarHBondContact OH-OH 2.94Å; Y176-T265 HydrophobicContact CD2-CG2 4.43Å; Y176-T265 HydrophobicContact CG-CG2 4.01Å; Y176-A268 HydrophobicContact CD2-CB 3.81Å; Y176-A268 HydrophobicContact CE2-CB 3.74Å
177	L	88.8	Confident	86.9	Confident	22 Å²	22	49.9 Å²	49.9	12%	0.115	23%	0.226	C	C	.	.	H	α-helix	trans	-60.7	-42.2	177.6	-69.1	173.4	0	0	0	111.8	L173 K174 R175 K181 L184 Y185 M188 L193	L173-L177 WeakPolarHBondContact O-CG 3.33Å; L173-L177 PolarHBondContact O-N 3.49Å; K174-L177 PolarHBondContact O-N 2.68Å; R175-L177 VanDerWaalsContact C-N 3.31Å; R175-L177 PolarHBondContact O-N 2.83Å; L177-K181 HydrophobicContact CD2-CB 4.49Å; L177-K181 CarbonylContact O-C 3.58Å; L177-K181 WeakPolarHBondContact O-CA 3.46Å; L177-K181 PolarHBondContact O-N 3.24Å; L177-K181 VanDerWaalsContact O-O 3.1Å; L177-L184 HydrophobicContact CD2-CD2 4.33Å; L177-Y185 HydrophobicContact CB-CD2 3.94Å; L177-Y185 HydrophobicContact CB-CG 4.41Å; L177-Y185 WeakPolarHBondContact O-CB 3.39Å; L177-M188 HydrophobicContact CD1-SD 4.28Å; L177-L193 HydrophobicContact CD1-CD2 4.15Å
178	A	84.5	Confident	86.7	Confident	6 Å²	6	52.8 Å²	52.8	5%	0.05	24%	0.24	C	C	.	.	H	α-helix	trans	-63.5	-40.5	179.2	0	0	0	0	0	113.2	K174 R175 Y176 Y185	K174-A178 PolarHBondContact O-N 3.08Å; K174-A178 VanDerWaalsContact O-N 3.08Å; R175-A178 PolarHBondContact O-N 3.35Å; Y176-A178 VanDerWaalsContact C-N 3.32Å; Y176-A178 PolarHBondContact O-N 3.17Å; A178-Y185 HydrophobicContact CB-CD1 3.84Å; A178-Y185 HydrophobicContact CB-CE1 3.71Å; A178-Y185 HydrophobicContact CB-CE2 4.48Å; A178-Y185 HydrophobicContact CB-CG 4.26Å
179	V	85.4	Confident	86.5	Confident	13 Å²	13	55.9 Å²	55.9	8%	0.079	27%	0.266	C	S	.	.	H	α-helix	trans	-88.7	-51	-175	175.1	0	0	0	0	112.2	R175 Y176 V269 H272 L273 F283	R175-V179 PolarHBondContact O-N 3.08Å; Y176-V179 PolarHBondContact O-N 3.05Å; V179-V269 HydrophobicContact CB-CG2 4.37Å; V179-V269 HydrophobicContact CG2-CG1 4.38Å; V179-H272 HydrophobicContact CG1-CB 4.04Å; V179-L273 HydrophobicContact CG1-CD2 3.67Å; V179-L273 HydrophobicContact CG1-CG 4Å; V179-L273 HydrophobicContact CG2-CD2 4.27Å; V179-F283 HydrophobicContact CG2-CD1 3.87Å; V179-F283 HydrophobicContact CG2-CE1 4.41Å
180	V	87.4	Confident	86.1	Confident	18 Å²	18	58.9 Å²	58.9	11%	0.109	28%	0.277	C	S	.	.	H	α-helix	trans	-87.5	-31.4	-169.4	-179	0	0	0	0	112	Y176 P182 A268 H272	Y176-V180 HydrophobicContact CD2-CB 3.82Å; Y176-V180 HydrophobicContact CD2-CG1 4.32Å; Y176-V180 HydrophobicContact CD2-CG2 3.5Å; Y176-V180 HydrophobicContact CE2-CB 3.62Å; Y176-V180 HydrophobicContact CE2-CG1 3.6Å; Y176-V180 HydrophobicContact CE2-CG2 3.63Å; Y176-V180 HydrophobicContact CG-CB 4.44Å; Y176-V180 HydrophobicContact CG-CG2 4.35Å; Y176-V180 VanDerWaalsContact O-CB 3.31Å; Y176-V180 WeakPolarHBondContact O-CB 3.36Å; Y176-V180 PolarHBondContact O-N 3.46Å; V180-P182 WeakPolarHBondContact O-CD 3.29Å; V180-A268 HydrophobicContact CG2-CB 4.27Å; V180-H272 HydrophobicContact CG2-CB 4.34Å
181	K	85.9	Confident	85.9	Confident	106 Å²	106	60.3 Å²	60.3	46%	0.461	29%	0.286	S	S	.	.			trans	-125.4	55.9	-178.2	-59	-64.1	-177.7	-172.6	0	112.1	Y176 L177 F183 L184 Y185	Y176-K181 HydrophobicContact CE1-CG 4.41Å; L177-K181 HydrophobicContact CD2-CB 4.49Å; L177-K181 CarbonylContact O-C 3.58Å; L177-K181 WeakPolarHBondContact O-CA 3.46Å; L177-K181 PolarHBondContact O-N 3.24Å; L177-K181 VanDerWaalsContact O-O 3.1Å; K181-F183 VanDerWaalsContact C-N 3.31Å; K181-F183 PolarHBondContact O-N 3.06Å; K181-L184 HydrophobicContact CB-CB 4.18Å; K181-L184 PolarHBondContact O-N 3.45Å; K181-L184 VanDerWaalsContact O-N 3.1Å; K181-Y185 PolarHBondContact O-N 2.92Å
182	P	81.7	Confident	85.9	Confident	28 Å²	28	62.5 Å²	62.5	18%	0.182	30%	0.302	C	S	.	.	H	α-helix	trans	-61.9	-33.6	-168.8	25.1	-35.6	0	0	0	113.8	V180 R186 F355	V180-P182 WeakPolarHBondContact O-CD 3.29Å; P182-R186 VanDerWaalsContact O-CB 3.26Å; P182-R186 WeakPolarHBondContact O-CB 3.46Å; P182-R186 PolarHBondContact O-N 2.93Å; P182-F355 HydrophobicContact CB-CE1 3.86Å; P182-F355 HydrophobicContact CB-CZ 4.28Å
183	F	82.3	Confident	85.7	Confident	126 Å²	126	63.2 Å²	63.2	55%	0.553	30%	0.304	S	S	*	.	H	α-helix	trans	-68.4	-41.3	177.3	-62.8	-69.9	0	0	0	112.7	K181 R187	K181-F183 VanDerWaalsContact C-N 3.31Å; K181-F183 PolarHBondContact O-N 3.06Å; F183-R187 PolarHBondContact O-N 2.98Å
184	L	84.8	Confident	85.5	Confident	95 Å²	95	59.7 Å²	59.7	50%	0.497	29%	0.286	S	S	.	.	H	α-helix	trans	-64.8	-50.2	175.2	180	62.6	0	0	0	109.4	L177 K181 R186 R187 M188	L177-L184 HydrophobicContact CD2-CD2 4.33Å; K181-L184 HydrophobicContact CB-CB 4.18Å; K181-L184 PolarHBondContact O-N 3.45Å; K181-L184 VanDerWaalsContact O-N 3.1Å; L184-R186 VanDerWaalsContact C-N 3.27Å; L184-R186 PolarHBondContact O-N 3.13Å; L184-R187 PolarHBondContact O-N 2.79Å; L184-M188 HydrophobicContact CG-CG 4.48Å; L184-M188 HydrophobicContact CG-SD 4.12Å; L184-M188 VanDerWaalsContact O-CG 3.29Å; L184-M188 WeakPolarHBondContact O-CG 3.39Å; L184-M188 PolarHBondContact O-N 2.98Å
185	Y	83.8	Confident	85.7	Confident	14 Å²	14	61.3 Å²	61.3	6%	0.055	30%	0.298	C	S	.	.	H	α-helix	trans	-60.1	-35.9	179.9	-178	-108.8	0	0	0	113	K174 L177 A178 K181 M188 L193 E352	K174-Y185 WeakPolarHBondContact CE-OH 3.08Å; K174-Y185 HydrophobicContact CG-CE2 4.13Å; L177-Y185 HydrophobicContact CB-CD2 3.94Å; L177-Y185 HydrophobicContact CB-CG 4.41Å; L177-Y185 WeakPolarHBondContact O-CB 3.39Å; A178-Y185 HydrophobicContact CB-CD1 3.84Å; A178-Y185 HydrophobicContact CB-CE1 3.71Å; A178-Y185 HydrophobicContact CB-CE2 4.48Å; A178-Y185 HydrophobicContact CB-CG 4.26Å; K181-Y185 PolarHBondContact O-N 2.92Å; Y185-M188 PolarHBondContact O-N 3.02Å; Y185-L193 HydrophobicContact CE2-CD2 4.38Å; Y185-E352 WeakPolarHBondContact CE1-OE1 3.34Å; Y185-E352 PolarHBondContact OH-OE1 3.33Å
186	R	80.8	Confident	86	Confident	176 Å²	176	68.4 Å²	68.4	66%	0.664	33%	0.325	S	S	*	.	H	α-helix	trans	-66.4	-35.2	173.9	-175.6	175.4	179.1	-169.2	-2.8	113.1	P182 L184	P182-R186 VanDerWaalsContact O-CB 3.26Å; P182-R186 WeakPolarHBondContact O-CB 3.46Å; P182-R186 PolarHBondContact O-N 2.93Å; L184-R186 VanDerWaalsContact C-N 3.27Å; L184-R186 PolarHBondContact O-N 3.13Å
187	R	84.1	Confident	86	Confident	230 Å²	230	67.9 Å²	67.9	87%	0.868	32%	0.324	S	S	*	.	H	α-helix	trans	-76.9	-24.6	177.9	-170.1	176.3	-179.1	-178.8	1.2	112.2	F183 L184	F183-R187 PolarHBondContact O-N 2.98Å; L184-R187 PolarHBondContact O-N 2.79Å
188	M	84.7	Confident	86.1	Confident	65 Å²	65	67.5 Å²	67.5	32%	0.32	32%	0.323	S	S	.	.	S	Bend	trans	-71.9	137.5	179.5	-70.4	176.3	106.9	0	0	111.9	L177 L184 Y185 K190 L193	L177-M188 HydrophobicContact CD1-SD 4.28Å; L184-M188 HydrophobicContact CG-CG 4.48Å; L184-M188 HydrophobicContact CG-SD 4.12Å; L184-M188 VanDerWaalsContact O-CG 3.29Å; L184-M188 WeakPolarHBondContact O-CG 3.39Å; L184-M188 PolarHBondContact O-N 2.98Å; Y185-M188 PolarHBondContact O-N 3.02Å; M188-K190 PolarHBondContact O-N 3.37Å; M188-L193 HydrophobicContact CE-CD1 3.94Å; M188-L193 HydrophobicContact CE-CD2 4.46Å; M188-L193 HydrophobicContact SD-CD2 4.36Å
189	A	85.6	Confident	86.5	Confident	67 Å²	67	70.8 Å²	70.8	55%	0.554	34%	0.342	S	S	*	.			trans	-70.1	100.2	167.9	0	0	0	0	0	109.3	T191 S192 L193	A189-T191 PolarHBondContact O-N 3.04Å; A189-T191 VanDerWaalsContact O-N 3.13Å; A189-S192 WeakPolarHBondContact O-CB 3.41Å; A189-S192 PolarHBondContact O-N 3.26Å; A189-L193 PolarHBondContact O-N 3.04Å
190	K	83.9	Confident	86.8	Confident	72 Å²	72	73.6 Å²	73.6	31%	0.313	36%	0.359	S	S	.	.	H	α-helix	trans	-52.9	-37.2	-175.2	-59.3	-176.9	-176.3	-174.5	0	113.2	S111 M188 A194 E352	S111-K190 WeakPolarHBondContact CB-O 3.24Å; S111-K190 PolarHBondContact OG-O 3.49Å; M188-K190 PolarHBondContact O-N 3.37Å; K190-A194 WeakPolarHBondContact O-CB 3.36Å; K190-A194 PolarHBondContact O-N 2.86Å; K190-E352 IonicContact NZ-OE2 2.94Å; K190-E352 PolarHBondContact NZ-OE2 2.64Å
191	T	85.4	Confident	87	Confident	54 Å²	54	72.9 Å²	72.9	33%	0.331	36%	0.355	S	S	.	.	H	α-helix	trans	-68.4	-45.7	176.9	-51.5	0	0	0	0	111.2	L110 A189 L193 A194 V195	L110-T191 HydrophobicContact CB-CG2 3.69Å; L110-T191 HydrophobicContact CD1-CG2 4.49Å; A189-T191 PolarHBondContact O-N 3.04Å; A189-T191 VanDerWaalsContact O-N 3.13Å; T191-L193 VanDerWaalsContact C-N 3.34Å; T191-L193 PolarHBondContact O-N 2.69Å; T191-A194 PolarHBondContact O-N 3.43Å; T191-V195 WeakPolarHBondContact O-CG2 3.49Å; T191-V195 PolarHBondContact O-N 3.49Å
192	S	88.1	Confident	87.4	Confident	58 Å²	58	71.8 Å²	71.8	41%	0.406	35%	0.348	S	S	.	.	H	α-helix	trans	-61.7	-42.6	176.3	-178.5	0	0	0	0	111.4	A189 A194 V195 W196	A189-S192 WeakPolarHBondContact O-CB 3.41Å; A189-S192 PolarHBondContact O-N 3.26Å; S192-A194 PolarHBondContact O-N 3.17Å; S192-V195 PolarHBondContact O-N 2.98Å; S192-W196 WeakPolarHBondContact O-CB 3.39Å; S192-W196 VanDerWaalsContact O-CD1 3.25Å; S192-W196 PolarHBondContact O-N 3.43Å
193	L	88.1	Confident	87.8	Confident	28 Å²	28	76.5 Å²	76.5	15%	0.147	37%	0.366	C	S	.	.	H	α-helix	trans	-59.1	-45.9	174.9	-179.5	63.5	0	0	0	111.8	L177 Y185 M188 A189 T191 W196 M197	L177-L193 HydrophobicContact CD1-CD2 4.15Å; Y185-L193 HydrophobicContact CE2-CD2 4.38Å; M188-L193 HydrophobicContact CE-CD1 3.94Å; M188-L193 HydrophobicContact CE-CD2 4.46Å; M188-L193 HydrophobicContact SD-CD2 4.36Å; A189-L193 PolarHBondContact O-N 3.04Å; T191-L193 VanDerWaalsContact C-N 3.34Å; T191-L193 PolarHBondContact O-N 2.69Å; L193-W196 PolarHBondContact O-N 3.45Å; L193-M197 HydrophobicContact CG-CE 4.15Å; L193-M197 HydrophobicContact CG-SD 4.44Å; L193-M197 VanDerWaalsContact O-CG 3.29Å; L193-M197 WeakPolarHBondContact O-CG 3.37Å; L193-M197 PolarHBondContact O-N 2.96Å
194	A	87.9	Confident	88.1	Confident	0 Å²	0	71.9 Å²	71.9	0%	0	35%	0.347	C	S	.	.	H	α-helix	trans	-62.2	-46.4	176.9	0	0	0	0	0	112.7	S111 L115 K190 T191 S192 W196 M197 C198	S111-A194 WeakPolarHBondContact OG-CB 3.35Å; L115-A194 HydrophobicContact CD1-CB 4.13Å; L115-A194 HydrophobicContact CD2-CB 4.34Å; L115-A194 HydrophobicContact CG-CB 3.95Å; K190-A194 WeakPolarHBondContact O-CB 3.36Å; K190-A194 PolarHBondContact O-N 2.86Å; T191-A194 PolarHBondContact O-N 3.43Å; S192-A194 PolarHBondContact O-N 3.17Å; A194-W196 PolarHBondContact O-N 2.87Å; A194-M197 HydrophobicContact CB-CE 4.46Å; A194-M197 PolarHBondContact O-N 2.94Å; A194-C198 PolarHBondContact O-N 3.39Å; A194-C198 PolarHBondContact O-SG 3.43Å; A194-C198 VanDerWaalsContact O-SG 3.38Å
195	V	90.2	Very high	88.4	Confident	64 Å²	64	68 Å²	68	39%	0.388	33%	0.325	S	S	.	.	H	α-helix	trans	-60.6	-46.1	177.2	171.7	0	0	0	0	110.6	V114 T191 S192 M197 C198 V199	V114-V195 HydrophobicContact CG1-CG2 4.23Å; V114-V195 HydrophobicContact CG2-CG2 4.34Å; T191-V195 WeakPolarHBondContact O-CG2 3.49Å; T191-V195 PolarHBondContact O-N 3.49Å; S192-V195 PolarHBondContact O-N 2.98Å; V195-M197 VanDerWaalsContact C-N 3.35Å; V195-M197 PolarHBondContact O-N 2.94Å; V195-C198 PolarHBondContact O-N 3Å; V195-V199 HydrophobicContact CG1-CG2 4.31Å; V195-V199 WeakPolarHBondContact O-CG2 3.48Å; V195-V199 PolarHBondContact O-N 3.06Å
196	W	91.9	Very high	88.7	Confident	166 Å²	166	68.5 Å²	68.5	63%	0.629	34%	0.336	S	S	*	.	H	α-helix	trans	-60.6	-42.4	177.1	-87.7	117.1	0	0	0	112.7	S192 L193 A194 V199 V200	S192-W196 WeakPolarHBondContact O-CB 3.39Å; S192-W196 VanDerWaalsContact O-CD1 3.25Å; S192-W196 PolarHBondContact O-N 3.43Å; L193-W196 PolarHBondContact O-N 3.45Å; A194-W196 PolarHBondContact O-N 2.87Å; W196-V199 HydrophobicContact CZ3-CG1 4.49Å; W196-V199 PolarHBondContact O-N 2.85Å; W196-V200 WeakPolarHBondContact O-CG2 3.26Å; W196-V200 PolarHBondContact O-N 3.17Å
197	M	90.8	Very high	89	Confident	18 Å²	18	61.2 Å²	61.2	9%	0.089	31%	0.313	C	S	.	.	H	α-helix	trans	-60.5	-46.4	174.9	-71.4	-176.1	-56.9	0	0	111.3	L115 C170 K174 L193 A194 V195 V199 V200 V201	L115-M197 HydrophobicContact CD1-CE 4.33Å; L115-M197 HydrophobicContact CD2-CE 4.11Å; C170-M197 HydrophobicContact CB-CB 4.17Å; C170-M197 HydrophobicContact CB-CG 4.19Å; C170-M197 HydrophobicContact CB-SD 3.77Å; K174-M197 HydrophobicContact CB-CE 4.39Å; K174-M197 HydrophobicContact CD-CE 4.22Å; L193-M197 HydrophobicContact CG-CE 4.15Å; L193-M197 HydrophobicContact CG-SD 4.44Å; L193-M197 VanDerWaalsContact O-CG 3.29Å; L193-M197 WeakPolarHBondContact O-CG 3.37Å; L193-M197 PolarHBondContact O-N 2.96Å; A194-M197 HydrophobicContact CB-CE 4.46Å; A194-M197 PolarHBondContact O-N 2.94Å; V195-M197 VanDerWaalsContact C-N 3.35Å; V195-M197 PolarHBondContact O-N 2.94Å; M197-V199 PolarHBondContact O-N 2.86Å; M197-V200 PolarHBondContact O-N 3.38Å; M197-V201 VanDerWaalsContact O-CG2 3.29Å; M197-V201 WeakPolarHBondContact O-CG2 3.46Å; M197-V201 PolarHBondContact O-N 3.07Å
198	C	91.6	Very high	89.1	Confident	13 Å²	13	50.4 Å²	50.4	9%	0.088	27%	0.273	C	S	.	.	H	α-helix	trans	-60.6	-45.2	175.9	-68.2	0	0	0	0	112.1	V114 A194 V195 V200 V201 W202	V114-C198 HydrophobicContact CG1-CB 4.48Å; A194-C198 PolarHBondContact O-N 3.39Å; A194-C198 PolarHBondContact O-SG 3.43Å; A194-C198 VanDerWaalsContact O-SG 3.38Å; V195-C198 PolarHBondContact O-N 3Å; C198-V200 VanDerWaalsContact C-N 3.33Å; C198-V200 PolarHBondContact O-N 3.34Å; C198-V201 PolarHBondContact O-N 3.45Å; C198-W202 PolarHBondContact O-N 3.37Å
199	V	93.1	Very high	89.3	Confident	75 Å²	75	48.8 Å²	48.8	46%	0.455	27%	0.265	S	S	.	.	H	α-helix	trans	-59	-44.4	177.9	169.1	0	0	0	0	111.3	V195 W196 M197 W202 F203	V195-V199 HydrophobicContact CG1-CG2 4.31Å; V195-V199 WeakPolarHBondContact O-CG2 3.48Å; V195-V199 PolarHBondContact O-N 3.06Å; W196-V199 HydrophobicContact CZ3-CG1 4.49Å; W196-V199 PolarHBondContact O-N 2.85Å; M197-V199 PolarHBondContact O-N 2.86Å; V199-W202 PolarHBondContact O-N 3.39Å; V199-F203 VanDerWaalsContact O-CB 3.3Å; V199-F203 WeakPolarHBondContact O-CB 3.3Å; V199-F203 PolarHBondContact O-N 3.01Å
200	V	91.1	Very high	89.4	Confident	73 Å²	73	48.3 Å²	48.3	44%	0.442	26%	0.255	S	S	.	.	H	α-helix	trans	-62.5	-45.6	177	170.1	0	0	0	0	111.1	W196 M197 C198 F203 L204	W196-V200 WeakPolarHBondContact O-CG2 3.26Å; W196-V200 PolarHBondContact O-N 3.17Å; M197-V200 PolarHBondContact O-N 3.38Å; C198-V200 VanDerWaalsContact C-N 3.33Å; C198-V200 PolarHBondContact O-N 3.34Å; V200-F203 PolarHBondContact O-N 3.34Å; V200-L204 HydrophobicContact CG1-CD1 3.92Å; V200-L204 WeakPolarHBondContact O-CB 3.49Å; V200-L204 VanDerWaalsContact O-CG 3.3Å; V200-L204 WeakPolarHBondContact O-CG 3.23Å; V200-L204 PolarHBondContact O-N 3.14Å
201	V	92.1	Very high	89.3	Confident	2 Å²	2	45.1 Å²	45.1	1%	0.012	24%	0.242	C	C	.	.	H	α-helix	trans	-60.8	-47.5	178.1	168	0	0	0	0	111.2	C163 Q166 M197 C198 F203 L204 Y205	C163-V201 HydrophobicContact CB-CG1 4.25Å; C163-V201 WeakPolarHBondContact SG-CG1 3.44Å; Q166-V201 HydrophobicContact CB-CG2 4.1Å; M197-V201 VanDerWaalsContact O-CG2 3.29Å; M197-V201 WeakPolarHBondContact O-CG2 3.46Å; M197-V201 PolarHBondContact O-N 3.07Å; C198-V201 PolarHBondContact O-N 3.45Å; V201-F203 PolarHBondContact O-N 3.41Å; V201-L204 PolarHBondContact O-N 3.49Å; V201-Y205 WeakPolarHBondContact O-CB 3.3Å; V201-Y205 PolarHBondContact O-N 3.15Å
202	W	93	Very high	89.3	Confident	83 Å²	83	43 Å²	43	31%	0.314	23%	0.228	S	C	.	.	H	α-helix	trans	-67.7	-34.9	179.1	-82.7	100.6	0	0	0	113.2	N118 L121 L125 C198 V199 Y205 G206	N118-W202 VanDerWaalsContact OD1-CD1 3.28Å; N118-W202 PolarHBondContact OD1-NE1 2.93Å; L121-W202 HydrophobicContact CD2-CH2 4.01Å; L121-W202 HydrophobicContact CD2-CZ2 3.62Å; L121-W202 HydrophobicContact CG-CH2 4.17Å; L121-W202 HydrophobicContact CG-CZ2 3.97Å; L125-W202 HydrophobicContact CD1-CH2 3.81Å; L125-W202 HydrophobicContact CD1-CZ3 4.34Å; C198-W202 PolarHBondContact O-N 3.37Å; V199-W202 PolarHBondContact O-N 3.39Å; W202-Y205 AromaticContact CE3-CD1 3.87Å; W202-Y205 HydrophobicContact CE3-CD1 3.87Å; W202-Y205 HydrophobicContact CE3-CE1 4.37Å; W202-Y205 HydrophobicContact CE3-CG 4.29Å; W202-Y205 AromaticContact CZ3-CD1 3.88Å; W202-Y205 HydrophobicContact CZ3-CD1 3.88Å; W202-Y205 AromaticContact CZ3-CE1 3.92Å; W202-Y205 HydrophobicContact CZ3-CE1 3.92Å; W202-Y205 HydrophobicContact CZ3-CG 4.4Å; W202-Y205 WeakPolarHBondContact O-CB 3.48Å; W202-Y205 PolarHBondContact O-N 2.89Å; W202-G206 PolarHBondContact O-N 3.5Å
203	F	90.8	Very high	89.2	Confident	128 Å²	128	43.2 Å²	43.2	56%	0.561	23%	0.225	S	C	*	.	H	α-helix	trans	-61.7	-46.7	172.7	174.3	-96	0	0	0	111.1	L8 V199 V200 V201 G206 A207	L8-F203 HydrophobicContact CD1-CE1 4.35Å; V199-F203 VanDerWaalsContact O-CB 3.3Å; V199-F203 WeakPolarHBondContact O-CB 3.3Å; V199-F203 PolarHBondContact O-N 3.01Å; V200-F203 PolarHBondContact O-N 3.34Å; V201-F203 PolarHBondContact O-N 3.41Å; F203-G206 PolarHBondContact O-N 2.94Å; F203-A207 PolarHBondContact O-N 3.42Å
204	L	88.8	Confident	89	Confident	28 Å²	28	46.8 Å²	46.8	15%	0.147	24%	0.243	C	C	.	.	H	α-helix	trans	-68.4	-36	178.3	-69.9	173	0	0	0	112.2	Q166 V200 V201 A207 A208 L253	Q166-L204 VanDerWaalsContact CD-CD1 3.49Å; Q166-L204 HydrophobicContact CG-CD1 4.47Å; V200-L204 HydrophobicContact CG1-CD1 3.92Å; V200-L204 WeakPolarHBondContact O-CB 3.49Å; V200-L204 VanDerWaalsContact O-CG 3.3Å; V200-L204 WeakPolarHBondContact O-CG 3.23Å; V200-L204 PolarHBondContact O-N 3.14Å; V201-L204 PolarHBondContact O-N 3.49Å; L204-A207 PolarHBondContact O-N 2.88Å; L204-A208 WeakPolarHBondContact O-CB 3.33Å; L204-A208 PolarHBondContact O-N 3.04Å; L204-L253 HydrophobicContact CD2-CD2 3.6Å; L204-L253 HydrophobicContact CD2-CG 4.26Å
205	Y	90.6	Very high	88.6	Confident	13 Å²	13	47.7 Å²	47.7	5%	0.051	25%	0.249	C	C	.	.	H	α-helix	trans	-56.5	-51.2	168.5	175	-89.6	0	0	0	110.7	L156 G159 C163 V201 W202 A207 A208 I209	L156-Y205 WeakPolarHBondContact CD2-OH 3.35Å; G159-Y205 VanDerWaalsContact O-CD2 3.26Å; G159-Y205 WeakPolarHBondContact O-CD2 3.45Å; C163-Y205 HydrophobicContact CB-CD2 3.75Å; C163-Y205 HydrophobicContact CB-CG 4.49Å; V201-Y205 WeakPolarHBondContact O-CB 3.3Å; V201-Y205 PolarHBondContact O-N 3.15Å; W202-Y205 AromaticContact CE3-CD1 3.87Å; W202-Y205 HydrophobicContact CE3-CD1 3.87Å; W202-Y205 HydrophobicContact CE3-CE1 4.37Å; W202-Y205 HydrophobicContact CE3-CG 4.29Å; W202-Y205 AromaticContact CZ3-CD1 3.88Å; W202-Y205 HydrophobicContact CZ3-CD1 3.88Å; W202-Y205 AromaticContact CZ3-CE1 3.92Å; W202-Y205 HydrophobicContact CZ3-CE1 3.92Å; W202-Y205 HydrophobicContact CZ3-CG 4.4Å; W202-Y205 WeakPolarHBondContact O-CB 3.48Å; W202-Y205 PolarHBondContact O-N 2.89Å; Y205-A207 VanDerWaalsContact C-N 3.33Å; Y205-A207 PolarHBondContact O-N 3.39Å; Y205-A208 PolarHBondContact O-N 3.24Å; Y205-A208 VanDerWaalsContact O-N 3.07Å; Y205-I209 HydrophobicContact CD1-CD1 4.36Å; Y205-I209 HydrophobicContact CD1-CG2 4.3Å; Y205-I209 HydrophobicContact CE1-CD1 3.95Å; Y205-I209 HydrophobicContact CE1-CG2 3.96Å; Y205-I209 HydrophobicContact CE2-CG2 4.3Å; Y205-I209 WeakPolarHBondContact O-CG2 3.26Å; Y205-I209 PolarHBondContact O-N 3Å
206	G	90.3	Very high	88.1	Confident	26 Å²	26	47.2 Å²	47.2	27%	0.268	24%	0.241	S	C	.	.	H	α-helix	trans	-53.7	-48.1	175	0	0	0	0	0	112.2	W202 F203 A208 I209 V210	W202-G206 PolarHBondContact O-N 3.5Å; F203-G206 PolarHBondContact O-N 2.94Å; G206-A208 VanDerWaalsContact C-N 3.3Å; G206-A208 PolarHBondContact O-N 2.94Å; G206-I209 WeakPolarHBondContact O-CG1 3.34Å; G206-I209 PolarHBondContact O-N 2.83Å; G206-V210 VanDerWaalsContact O-CG2 3.25Å; G206-V210 WeakPolarHBondContact O-CG2 3.37Å; G206-V210 PolarHBondContact O-N 2.88Å
207	A	86.8	Confident	87.7	Confident	23 Å²	23	39.6 Å²	39.6	19%	0.19	21%	0.213	C	C	.	.	H	α-helix	trans	-62.4	-36	177.3	0	0	0	0	0	113	L8 F203 L204 Y205 P211	L8-A207 HydrophobicContact CD2-CB 3.86Å; F203-A207 PolarHBondContact O-N 3.42Å; L204-A207 PolarHBondContact O-N 2.88Å; Y205-A207 VanDerWaalsContact C-N 3.33Å; Y205-A207 PolarHBondContact O-N 3.39Å; A207-P211 WeakPolarHBondContact O-CD 3.41Å
208	A	85.8	Confident	87.4	Confident	3 Å²	3	39 Å²	39	3%	0.025	21%	0.211	C	C	.	.	H	α-helix	trans	-73	-34.4	179.8	0	0	0	0	0	113.3	Y162 L204 Y205 G206 P211 L250	Y162-A208 HydrophobicContact CD2-CB 3.62Å; Y162-A208 HydrophobicContact CE2-CB 4.2Å; Y162-A208 HydrophobicContact CG-CB 4.43Å; L204-A208 WeakPolarHBondContact O-CB 3.33Å; L204-A208 PolarHBondContact O-N 3.04Å; Y205-A208 PolarHBondContact O-N 3.24Å; Y205-A208 VanDerWaalsContact O-N 3.07Å; G206-A208 VanDerWaalsContact C-N 3.3Å; G206-A208 PolarHBondContact O-N 2.94Å; A208-P211 WeakPolarHBondContact O-CD 3.38Å; A208-P211 WeakPolarHBondContact O-CG 3.26Å; A208-L250 HydrophobicContact CB-CD2 4.01Å
209	I	89.4	Confident	86.8	Confident	31 Å²	31	38.4 Å²	38.4	16%	0.159	21%	0.207	C	C	.	.	H	α-helix	trans	-77.5	-30.3	-179.4	64.9	168.7	0	0	0	113.2	A155 Y205 G206 E212 L213	A155-I209 HydrophobicContact CB-CB 4Å; A155-I209 HydrophobicContact CB-CG2 4.3Å; A155-I209 VanDerWaalsContact O-CG2 3.24Å; A155-I209 WeakPolarHBondContact O-CG2 3.48Å; Y205-I209 HydrophobicContact CD1-CD1 4.36Å; Y205-I209 HydrophobicContact CD1-CG2 4.3Å; Y205-I209 HydrophobicContact CE1-CD1 3.95Å; Y205-I209 HydrophobicContact CE1-CG2 3.96Å; Y205-I209 HydrophobicContact CE2-CG2 4.3Å; Y205-I209 WeakPolarHBondContact O-CG2 3.26Å; Y205-I209 PolarHBondContact O-N 3Å; G206-I209 WeakPolarHBondContact O-CG1 3.34Å; G206-I209 PolarHBondContact O-N 2.83Å; I209-E212 WeakPolarHBondContact O-CB 3.5Å; I209-E212 PolarHBondContact O-N 3.33Å; I209-L213 HydrophobicContact CB-CD1 4.47Å; I209-L213 HydrophobicContact CD1-CD1 4.18Å; I209-L213 HydrophobicContact CG1-CD1 4.31Å; I209-L213 WeakPolarHBondContact O-CG 3.44Å; I209-L213 PolarHBondContact O-N 2.93Å
210	V	87.4	Confident	86.1	Confident	57 Å²	57	36.9 Å²	36.9	35%	0.345	19%	0.194	S	C	.	.	H	α-helix	trans	-49.8	-53.9	-179	165.9	0	0	0	0	113.3	G206 E212 L213 L214	G206-V210 VanDerWaalsContact O-CG2 3.25Å; G206-V210 WeakPolarHBondContact O-CG2 3.37Å; G206-V210 PolarHBondContact O-N 2.88Å; V210-E212 PolarHBondContact O-N 3.11Å; V210-L213 PolarHBondContact O-N 3.01Å; V210-L213 VanDerWaalsContact O-N 3.14Å; V210-L214 HydrophobicContact CG1-CD1 3.68Å; V210-L214 HydrophobicContact CG1-CG 4.28Å; V210-L214 WeakPolarHBondContact O-CG 3.35Å; V210-L214 PolarHBondContact O-N 3.45Å
211	P	82.5	Confident	85.4	Confident	5 Å²	5	33.5 Å²	33.5	3%	0.032	17%	0.174	C	C	.	.	H	α-helix	trans	-64.2	-27.5	180	23.6	-33.8	0	0	0	113.4	A207 A208 V215 L243 L250	A207-P211 WeakPolarHBondContact O-CD 3.41Å; A208-P211 WeakPolarHBondContact O-CD 3.38Å; A208-P211 WeakPolarHBondContact O-CG 3.26Å; P211-V215 WeakPolarHBondContact O-CB 3.37Å; P211-V215 WeakPolarHBondContact O-CG2 3.27Å; P211-L243 HydrophobicContact CB-CD1 3.45Å; P211-L243 VanDerWaalsContact CB-CD1 3.45Å; P211-L250 HydrophobicContact CG-CD1 3.59Å
212	E	84.4	Confident	84.2	Confident	8 Å²	8	38.2 Å²	38.2	4%	0.037	19%	0.191	C	C	.	.	H	α-helix	trans	-73.4	-33.1	175.6	-56.7	-62.1	177.2	0	0	112.3	T154 A155 I209 V210 Q217 K247	T154-E212 HydrophobicContact CG2-CG 4.48Å; A155-E212 HydrophobicContact CB-CB 3.69Å; A155-E212 HydrophobicContact CB-CG 4.49Å; I209-E212 WeakPolarHBondContact O-CB 3.5Å; I209-E212 PolarHBondContact O-N 3.33Å; V210-E212 PolarHBondContact O-N 3.11Å; E212-Q217 PolarHBondContact O-NE2 2.64Å; E212-Q217 PolarHBondContact OE2-NE2 2.95Å; E212-K247 IonicContact OE1-NZ 2.79Å; E212-K247 PolarHBondContact OE1-NZ 3.35Å; E212-K247 IonicContact OE2-NZ 3.73Å; E212-K247 PolarHBondContact OE2-NZ 2.85Å
213	L	87.1	Confident	83.1	Confident	64 Å²	64	41.7 Å²	41.7	34%	0.335	20%	0.204	S	C	.	.	H	α-helix	trans	-78.8	-31.4	-179.8	-67.6	174.1	0	0	0	113.5	R151 A155 I209 V210	R151-L213 HydrophobicContact CB-CD2 4.39Å; R151-L213 VanDerWaalsContact CD-O 3.22Å; R151-L213 WeakPolarHBondContact CD-O 3.37Å; R151-L213 PolarHBondContact NH1-O 3.2Å; A155-L213 HydrophobicContact CB-CD2 3.65Å; A155-L213 HydrophobicContact CB-CG 3.76Å; I209-L213 HydrophobicContact CB-CD1 4.47Å; I209-L213 HydrophobicContact CD1-CD1 4.18Å; I209-L213 HydrophobicContact CG1-CD1 4.31Å; I209-L213 WeakPolarHBondContact O-CG 3.44Å; I209-L213 PolarHBondContact O-N 2.93Å; V210-L213 PolarHBondContact O-N 3.01Å; V210-L213 VanDerWaalsContact O-N 3.14Å
214	L	83	Confident	82.1	Confident	102 Å²	102	38.6 Å²	38.6	53%	0.534	19%	0.193	S	C	.	.	H	α-helix	trans	-77.4	-26.7	-178.1	-68.8	177.3	0	0	0	112.7	A15 R151 V210	A15-L214 HydrophobicContact CB-CD1 3.73Å; R151-L214 PolarHBondContact NH1-O 3.31Å; V210-L214 HydrophobicContact CG1-CD1 3.68Å; V210-L214 HydrophobicContact CG1-CG 4.28Å; V210-L214 WeakPolarHBondContact O-CG 3.35Å; V210-L214 PolarHBondContact O-N 3.45Å
215	V	79.6	Confident	81.6	Confident	20 Å²	20	44.9 Å²	44.9	12%	0.121	22%	0.222	C	C	.	.	S	Bend	trans	-100.6	146.6	-168.5	176.7	0	0	0	0	110.2	R151 P211 Q217 L243	R151-V215 WeakPolarHBondContact CD-O 3.12Å; R151-V215 PolarHBondContact NE-O 2.99Å; R151-V215 VanDerWaalsContact NE-O 3.12Å; P211-V215 WeakPolarHBondContact O-CB 3.37Å; P211-V215 WeakPolarHBondContact O-CG2 3.27Å; V215-Q217 PolarHBondContact O-N 3.02Å; V215-L243 HydrophobicContact CB-CD2 4.24Å; V215-L243 HydrophobicContact CG1-CD2 4.18Å; V215-L243 HydrophobicContact CG2-CD1 4.26Å; V215-L243 HydrophobicContact CG2-CD2 3.18Å; V215-L243 HydrophobicContact CG2-CG 4.36Å
216	K	80.3	Confident	81.2	Confident	53 Å²	53	45.3 Å²	45.3	23%	0.23	23%	0.225	C	C	.	.			trans	-67.9	129.9	174.6	-170.3	179.4	-179.1	126.4	0	110.2	P56 E147 S218 Y219	P56-K216 HydrophobicContact CG-CD 4.18Å; P56-K216 VanDerWaalsContact CG-CE 3.42Å; E147-K216 WeakPolarHBondContact OE1-CA 3.44Å; E147-K216 VanDerWaalsContact OE1-CG 3.26Å; E147-K216 WeakPolarHBondContact OE1-CG 3.28Å; K216-S218 WeakPolarHBondContact CE-O 3.49Å; K216-Y219 HydrophobicContact CD-CE1 3.92Å; K216-Y219 HydrophobicContact CG-CE1 4.44Å; K216-Y219 HydrophobicContact CG-CE2 4.31Å
217	Q	82.9	Confident	80.9	Confident	6 Å²	6	45.2 Å²	45.2	3%	0.028	22%	0.219	C	C	.	.			trans	-116.5	-22.6	-173.9	-62.3	-74.8	-18.5	0	0	112.8	E147 C150 R151 E212 V215 H230	E147-Q217 PolarHBondContact OE1-N 3.32Å; C150-Q217 WeakPolarHBondContact SG-CB 3.48Å; R151-Q217 HydrophobicContact CB-CG 4.47Å; R151-Q217 HydrophobicContact CG-CB 4.19Å; R151-Q217 HydrophobicContact CG-CG 3.87Å; E212-Q217 PolarHBondContact O-NE2 2.64Å; E212-Q217 PolarHBondContact OE2-NE2 2.95Å; V215-Q217 PolarHBondContact O-N 3.02Å; Q217-H230 PolarHBondContact O-N 3.16Å; Q217-H230 PolarHBondContact OE1-ND1 3.35Å
218	S	84.1	Confident	80.8	Confident	7 Å²	7	44.1 Å²	44.1	5%	0.049	21%	0.21	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-103.8	135.8	176.9	75.8	0	0	0	0	113.2	E147 K216 T228	E147-S218 WeakPolarHBondContact OE2-CA 3.46Å; E147-S218 WeakPolarHBondContact OE2-CB 3.22Å; E147-S218 PolarHBondContact OE2-N 3.37Å; E147-S218 PolarHBondContact OE2-OG 3.33Å; K216-S218 WeakPolarHBondContact CE-O 3.49Å; S218-T228 VanDerWaalsContact CA-O 3.23Å; S218-T228 WeakPolarHBondContact CA-O 3.46Å
219	Y	80.8	Confident	80.9	Confident	0 Å²	0	44.4 Å²	44.4	0%	0	21%	0.212	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-138.7	137.5	179.6	-66.6	-85.9	0	0	0	110	F37 L58 K216 T227 T228 V232 L233 P234	F37-Y219 HydrophobicContact CZ-CE1 4.29Å; L58-Y219 HydrophobicContact CD1-CD1 3.77Å; L58-Y219 HydrophobicContact CD1-CE1 4.48Å; L58-Y219 HydrophobicContact CD1-CG 4.34Å; K216-Y219 HydrophobicContact CD-CE1 3.92Å; K216-Y219 HydrophobicContact CG-CE1 4.44Å; K216-Y219 HydrophobicContact CG-CE2 4.31Å; Y219-T227 CarbonylContact O-C 3.57Å; Y219-T227 WeakPolarHBondContact O-CA 3.25Å; Y219-T228 PolarHBondContact N-O 3.4Å; Y219-T228 VanDerWaalsContact N-O 3.09Å; Y219-T228 PolarHBondContact O-N 2.72Å; Y219-T228 PolarHBondContact O-OG1 2.97Å; Y219-V232 VanDerWaalsContact CD2-O 3.32Å; Y219-V232 WeakPolarHBondContact CD2-O 3.06Å; Y219-L233 HydrophobicContact CD2-CD1 3.98Å; Y219-L233 HydrophobicContact CD2-CG 4.49Å; Y219-L233 HydrophobicContact CE2-CD1 3.41Å; Y219-L233 VanDerWaalsContact CE2-CD1 3.41Å; Y219-L233 HydrophobicContact CE2-CG 3.75Å; Y219-P234 HydrophobicContact CD1-CG 3.86Å; Y219-P234 HydrophobicContact CE1-CG 3.33Å; Y219-P234 HydrophobicContact CE2-CG 4.46Å
220	H	78	Confident	80.6	Confident	43 Å²	43	43.8 Å²	43.8	20%	0.199	21%	0.208	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-89.8	120	178.5	-175.7	-71.1	0	0	0	110.3	V55 P56 H57 L58	V55-H220 HydrophobicContact CG1-CB 3.59Å; P56-H220 PolarHBondContact O-N 3.38Å; H57-H220 AromaticContact ND1-ND1 3.82Å; L58-H220 PolarHBondContact N-O 2.91Å
221	I	76.1	Confident	79.8	Confident	2 Å²	2	41.1 Å²	41.1	1%	0.01	19%	0.192	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-90.6	108.1	175.5	-54.9	178.8	0	0	0	107.8	V60 R223 L224 E225 I226 T228 V232	V60-I221 HydrophobicContact CB-CG2 4.35Å; V60-I221 HydrophobicContact CG2-CD1 4.43Å; V60-I221 HydrophobicContact CG2-CG2 4.09Å; I221-R223 PolarHBondContact O-N 3.34Å; I221-L224 HydrophobicContact CB-CB 4.44Å; I221-L224 HydrophobicContact CD1-CD1 4.37Å; I221-L224 HydrophobicContact CG2-CB 4.15Å; I221-L224 HydrophobicContact CG2-CD1 4.08Å; I221-L224 HydrophobicContact CG2-CG 4.23Å; I221-L224 PolarHBondContact O-N 2.82Å; I221-E225 PolarHBondContact O-N 2.95Å; I221-I226 HydrophobicContact CB-CG1 4.34Å; I221-I226 HydrophobicContact CD1-CG1 4.45Å; I221-I226 PolarHBondContact N-O 3.43Å; I221-I226 PolarHBondContact O-N 3.37Å; I221-T228 HydrophobicContact CD1-CG2 3.45Å; I221-T228 VanDerWaalsContact CD1-CG2 3.45Å; I221-T228 HydrophobicContact CG1-CG2 4.22Å; I221-V232 HydrophobicContact CD1-CB 4.47Å; I221-V232 HydrophobicContact CD1-CG2 3.97Å
222	R	66.6	Low	78.9	Confident	101 Å²	101	40.9 Å²	40.9	38%	0.381	19%	0.191	S	C	.	.	G	3₁₀ helix	trans	-58.5	-44.6	-174	-84.2	-177.5	174.1	166.8	-0	113	D38 H57 L58 L224 E225	D38-R222 IonicContact OD2-NH1 2.81Å; D38-R222 PolarHBondContact OD2-NH1 3.27Å; H57-R222 HydrophobicContact CB-CG 3.89Å; H57-R222 VanDerWaalsContact CB-NE 3.28Å; H57-R222 PolarHBondContact CD2-NH2 2.98Å; H57-R222 PolarHBondContact ND1-NE 2.95Å; L58-R222 PolarHBondContact O-N 3.06Å; R222-L224 VanDerWaalsContact C-N 3.32Å; R222-L224 PolarHBondContact O-N 3.32Å; R222-E225 PolarHBondContact O-N 3Å
223	R	69	Low	78	Confident	155 Å²	155	41 Å²	41	59%	0.585	19%	0.191	S	C	*	.	G	3₁₀ helix	trans	-69.3	-26.9	-174.4	-63.9	-177.5	-175.5	-155	-5.8	114.9	D59 V60 I221	D59-R223 WeakPolarHBondContact OD1-CG 3.28Å; D59-R223 IonicContact OD1-CZ 2.87Å; D59-R223 IonicContact OD1-NE 3.86Å; D59-R223 PolarHBondContact OD1-NE 2.83Å; D59-R223 IonicContact OD1-NH2 3.61Å; V60-R223 WeakPolarHBondContact O-CD 3.38Å; I221-R223 PolarHBondContact O-N 3.34Å
224	L	70	Confident	76.4	Confident	64 Å²	64	38.1 Å²	38.1	34%	0.335	18%	0.176	S	C	.	.	G	3₁₀ helix	trans	-99.9	-6.9	179.4	-69.3	170.4	0	0	0	111.5	T71 I221 R222 I226	T71-L224 HydrophobicContact CG2-CD2 4.36Å; I221-L224 HydrophobicContact CB-CB 4.44Å; I221-L224 HydrophobicContact CD1-CD1 4.37Å; I221-L224 HydrophobicContact CG2-CB 4.15Å; I221-L224 HydrophobicContact CG2-CD1 4.08Å; I221-L224 HydrophobicContact CG2-CG 4.23Å; I221-L224 PolarHBondContact O-N 2.82Å; R222-L224 VanDerWaalsContact C-N 3.32Å; R222-L224 PolarHBondContact O-N 3.32Å; L224-I226 HydrophobicContact CB-CD1 3.97Å; L224-I226 HydrophobicContact CB-CG1 3.71Å; L224-I226 HydrophobicContact CD1-CD1 3.96Å; L224-I226 HydrophobicContact CD1-CG1 4.45Å; L224-I226 WeakPolarHBondContact O-CG2 3.45Å; L224-I226 PolarHBondContact O-N 2.94Å; L224-I226 VanDerWaalsContact O-N 3.12Å
225	E	80	Confident	74.9	Confident	160 Å²	160	34.6 Å²	34.6	75%	0.748	16%	0.158	S	C	*	.	T	Hydrogen-bonded Turn	trans	49.9	32.1	-173.1	-59.2	-169.3	148.2	0	0	113.7	I221 R222	I221-E225 PolarHBondContact O-N 2.95Å; R222-E225 PolarHBondContact O-N 3Å
226	I	82	Confident	73.6	Confident	22 Å²	22	38.8 Å²	38.8	11%	0.113	18%	0.176	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-116.7	146.4	178.8	64.9	-179.9	0	0	0	111.5	N141 N142 I221 L224 T228	N141-I226 HydrophobicContact CB-CD1 4.45Å; N142-I226 HydrophobicContact CB-CB 4.13Å; N142-I226 HydrophobicContact CB-CG2 3.99Å; I221-I226 HydrophobicContact CB-CG1 4.34Å; I221-I226 HydrophobicContact CD1-CG1 4.45Å; I221-I226 PolarHBondContact N-O 3.43Å; I221-I226 PolarHBondContact O-N 3.37Å; L224-I226 HydrophobicContact CB-CD1 3.97Å; L224-I226 HydrophobicContact CB-CG1 3.71Å; L224-I226 HydrophobicContact CD1-CD1 3.96Å; L224-I226 HydrophobicContact CD1-CG1 4.45Å; L224-I226 WeakPolarHBondContact O-CG2 3.45Å; L224-I226 PolarHBondContact O-N 2.94Å; L224-I226 VanDerWaalsContact O-N 3.12Å; I226-T228 HydrophobicContact CD1-CG2 4.03Å; I226-T228 HydrophobicContact CG1-CG2 4.26Å
227	T	83.9	Confident	72.1	Confident	23 Å²	23	39.5 Å²	39.5	14%	0.141	18%	0.18	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-96.2	106.9	167	-59.4	0	0	0	0	109	N142 W143 Y219	N142-T227 PolarHBondContact OD1-N 2.94Å; W143-T227 HydrophobicContact CB-CG2 4.45Å; W143-T227 VanDerWaalsContact CB-O 3.29Å; W143-T227 WeakPolarHBondContact CB-O 3.16Å; W143-T227 PolarHBondContact N-O 3.32Å; Y219-T227 CarbonylContact O-C 3.57Å; Y219-T227 WeakPolarHBondContact O-CA 3.25Å
228	T	84.1	Confident	70.3	Confident	0 Å²	0	44.8 Å²	44.8	0%	0	22%	0.216	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-77.9	144.6	174.9	53.6	0	0	0	0	110.7	T70 Y136 S218 Y219 I221 I226 V232	T70-T228 HydrophobicContact CG2-CG2 4.48Å; Y136-T228 WeakPolarHBondContact OH-CA 3.35Å; S218-T228 VanDerWaalsContact CA-O 3.23Å; S218-T228 WeakPolarHBondContact CA-O 3.46Å; Y219-T228 PolarHBondContact N-O 3.4Å; Y219-T228 VanDerWaalsContact N-O 3.09Å; Y219-T228 PolarHBondContact O-N 2.72Å; Y219-T228 PolarHBondContact O-OG1 2.97Å; I221-T228 HydrophobicContact CD1-CG2 3.45Å; I221-T228 VanDerWaalsContact CD1-CG2 3.45Å; I221-T228 HydrophobicContact CG1-CG2 4.22Å; I226-T228 HydrophobicContact CD1-CG2 4.03Å; I226-T228 HydrophobicContact CG1-CG2 4.26Å; T228-V232 HydrophobicContact CG2-CG2 4.21Å
229	C	87	Confident	68.7	Low	10 Å²	10	46.8 Å²	46.8	7%	0.068	23%	0.229	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-114	118.4	172.9	176	0	0	0	0	108.9	Y136 W143 C150 D231	Y136-C229 HydrophobicContact CE2-CB 4.22Å; Y136-C229 PolarHBondContact OH-N 2.99Å; W143-C229 HydrophobicContact CB-CB 3.83Å; W143-C229 HydrophobicContact CD2-CB 3.88Å; W143-C229 HydrophobicContact CE3-CB 4.04Å; W143-C229 HydrophobicContact CG-CB 3.78Å; C150-C229 WeakPolarHBondContact CA-SG 3.44Å; C150-C229 HydrophobicContact CB-CB 4.01Å; C150-C229 WeakPolarHBondContact CB-SG 3.23Å; C150-C229 WeakPolarHBondContact SG-CA 3.39Å; C150-C229 WeakPolarHBondContact SG-CB 3.48Å; C150-C229 CovalentContact SG-SG 2.03Å; C150-C229 PolarHBondContact SG-SG 3.4Å; C229-D231 PolarHBondContact O-N 3.38Å
230	H	83.2	Confident	67.4	Low	17 Å²	17	47.8 Å²	47.8	8%	0.079	23%	0.234	C	C	.	.	S	Bend	trans	65.8	-25.7	180	-173.2	75.1	0	0	0	116.3	S32 T154 F158 Q217 V232	S32-H230 PolarHBondContact OG-O 3.32Å; T154-H230 HydrophobicContact CG2-CB 3.97Å; T154-H230 VanDerWaalsContact CG2-ND1 3.29Å; T154-H230 WeakPolarHBondContact CG2-ND1 3.24Å; F158-H230 AromaticContact CE2-CD2 3.63Å; F158-H230 AromaticContact CE2-CE1 3.5Å; F158-H230 VanDerWaalsContact CE2-CE1 3.5Å; F158-H230 WeakPolarHBondContact CE2-CE1 3.36Å; F158-H230 AromaticContact CE2-NE2 3.11Å; F158-H230 WeakPolarHBondContact CE2-NE2 3.43Å; F158-H230 AromaticContact CZ-CD2 3.98Å; F158-H230 AromaticContact CZ-NE2 3.35Å; F158-H230 WeakPolarHBondContact CZ-NE2 3.35Å; Q217-H230 PolarHBondContact O-N 3.16Å; Q217-H230 PolarHBondContact OE1-ND1 3.35Å; H230-V232 PolarHBondContact O-N 3.13Å
231	D	71	Confident	66.4	Low	2 Å²	2	49.2 Å²	49.2	1%	0.011	25%	0.249	C	C	.	.	S	Bend	trans	-73.6	-21.7	-171.7	-70.2	-10.3	0	0	0	114.5	S32 Y136 H137 C229 Y321 R325	S32-D231 WeakPolarHBondContact CB-O 3.28Å; Y136-D231 WeakPolarHBondContact CE1-OD2 3.44Å; Y136-D231 PolarHBondContact OH-OD2 2.89Å; H137-D231 IonicContact CE1-OD2 3.54Å; C229-D231 PolarHBondContact O-N 3.38Å; D231-Y321 PolarHBondContact OD1-OH 2.87Å; D231-Y321 VanDerWaalsContact OD1-OH 3.12Å; D231-R325 IonicContact OD1-CZ 3.69Å; D231-R325 IonicContact OD1-NH1 3.88Å; D231-R325 PolarHBondContact OD1-NH1 2.92Å; D231-R325 IonicContact OD1-NH2 2.99Å
232	V	64.9	Low	65.8	Low	0 Å²	0	51.2 Å²	51.2	0%	0	26%	0.262	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-136.3	131	177.7	-176.9	0	0	0	0	110	L58 Y219 I221 T228 H230	L58-V232 HydrophobicContact CD2-CG1 3.79Å; Y219-V232 VanDerWaalsContact CD2-O 3.32Å; Y219-V232 WeakPolarHBondContact CD2-O 3.06Å; I221-V232 HydrophobicContact CD1-CB 4.47Å; I221-V232 HydrophobicContact CD1-CG2 3.97Å; T228-V232 HydrophobicContact CG2-CG2 4.21Å; H230-V232 PolarHBondContact O-N 3.13Å
233	L	63.9	Low	65.8	Low	9 Å²	9	47.5 Å²	47.5	5%	0.047	25%	0.25	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-135.7	132.6	179.4	-127.9	81.3	0	0	0	111.9	K31 Y219	K31-L233 HydrophobicContact CB-CD2 4.49Å; Y219-L233 HydrophobicContact CD2-CD1 3.98Å; Y219-L233 HydrophobicContact CD2-CG 4.49Å; Y219-L233 HydrophobicContact CE2-CD1 3.41Å; Y219-L233 VanDerWaalsContact CE2-CD1 3.41Å; Y219-L233 HydrophobicContact CE2-CG 3.75Å
234	P	54.1	Low	65.7	Low	4 Å²	4	41.2 Å²	41.2	3%	0.026	23%	0.228	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-74.9	141.6	177.6	26.6	-29.7	0	0	0	113.1	G35 F37 L58 Y219	G35-P234 WeakPolarHBondContact O-CA 3.37Å; F37-P234 HydrophobicContact CD2-CB 3.58Å; F37-P234 HydrophobicContact CD2-CG 4.08Å; F37-P234 HydrophobicContact CE2-CB 3.29Å; F37-P234 HydrophobicContact CE2-CG 3.27Å; F37-P234 HydrophobicContact CZ-CB 4.05Å; F37-P234 HydrophobicContact CZ-CG 3.57Å; L58-P234 HydrophobicContact CD1-CB 3.77Å; L58-P234 HydrophobicContact CD1-CG 3.71Å; L58-P234 HydrophobicContact CD2-CB 4.09Å; L58-P234 HydrophobicContact CD2-CG 4.41Å; L58-P234 HydrophobicContact CG-CB 4.3Å; Y219-P234 HydrophobicContact CD1-CG 3.86Å; Y219-P234 HydrophobicContact CE1-CG 3.33Å; Y219-P234 HydrophobicContact CE2-CG 4.46Å
235	L	52.3	Low	65.9	Low	29 Å²	29	43.3 Å²	43.3	15%	0.152	24%	0.239	C	C	.	.	S	Bend	trans	-83.7	-18.5	-171	-76.6	85.3	0	0	0	114.9	P30 K34 G35 E237	P30-L235 HydrophobicContact CB-CD1 3.7Å; P30-L235 HydrophobicContact CB-CD2 3.85Å; P30-L235 HydrophobicContact CB-CG 3.5Å; P30-L235 HydrophobicContact CG-CD1 4Å; P30-L235 HydrophobicContact CG-CD2 3.46Å; P30-L235 VanDerWaalsContact CG-CD2 3.46Å; P30-L235 HydrophobicContact CG-CG 3.73Å; K34-L235 HydrophobicContact CB-CD1 4.01Å; K34-L235 HydrophobicContact CD-CD1 4.38Å; K34-L235 HydrophobicContact CD-CD2 4.19Å; K34-L235 HydrophobicContact CG-CD1 3.21Å; K34-L235 HydrophobicContact CG-CD2 3.79Å; K34-L235 HydrophobicContact CG-CG 4.12Å; G35-L235 WeakPolarHBondContact O-CD1 3.46Å; L235-E237 VanDerWaalsContact C-N 3.29Å; L235-E237 PolarHBondContact O-N 3.48Å
236	E	51	Low	65.7	Low	108 Å²	108	36.4 Å²	36.4	51%	0.505	21%	0.208	S	C	.	.			trans	-87.9	-0.5	-159	-60	-172.3	153.7	0	0	113.3	P238	E236-P238 WeakPolarHBondContact O-CD 3.25Å
237	E	50.1	Low	65.4	Low	67 Å²	67	35.7 Å²	35.7	31%	0.313	20%	0.204	S	C	.	.			trans	-84.8	116.9	-180	-80.9	-172.6	-172.3	0	0	112	F37 L235 S239 H240	F37-E237 HydrophobicContact CE2-CG 4.29Å; L235-E237 VanDerWaalsContact C-N 3.29Å; L235-E237 PolarHBondContact O-N 3.48Å; E237-S239 PolarHBondContact O-N 3.31Å; E237-S239 VanDerWaalsContact O-N 3.1Å; E237-H240 WeakPolarHBondContact CB-CD2 3.14Å; E237-H240 PolarHBondContact O-CD2 2.98Å; E237-H240 PolarHBondContact O-N 3.12Å; E237-H240 IonicContact OE2-CD2 2.58Å; E237-H240 IonicContact OE2-NE2 3.98Å; E237-H240 PolarHBondContact OE2-NE2 3.23Å
238	P	45.4	Very low	65.1	Low	118 Å²	118	37.5 Å²	37.5	77%	0.766	21%	0.213	S	C	*	.	G	3₁₀ helix	trans	-66.1	-12.7	-178.6	23.9	-32.1	0	0	0	114.6	E236 H240	E236-P238 WeakPolarHBondContact O-CD 3.25Å; P238-H240 PolarHBondContact O-N 3.26Å
239	S	48.6	Very low	65	Low	48 Å²	48	40.1 Å²	40.1	34%	0.336	23%	0.226	S	C	.	.	G	3₁₀ helix	trans	-67.7	-9.8	175.9	51.1	0	0	0	0	114.1	E237	E237-S239 PolarHBondContact O-N 3.31Å; E237-S239 VanDerWaalsContact O-N 3.1Å
240	H	54.7	Low	64.8	Low	22 Å²	22	40.4 Å²	40.4	10%	0.102	23%	0.227	C	C	.	.	G	3₁₀ helix	trans	-96.6	-12.5	-169.8	-74.9	-90.2	0	0	0	115.9	K31 E237 P238 L243 V244	K31-H240 PolarHBondContact NZ-ND1 3.02Å; K31-H240 VanDerWaalsContact NZ-ND1 3.15Å; K31-H240 PolarHBondContact NZ-O 3.42Å; E237-H240 WeakPolarHBondContact CB-CD2 3.14Å; E237-H240 PolarHBondContact O-CD2 2.98Å; E237-H240 PolarHBondContact O-N 3.12Å; E237-H240 IonicContact OE2-CD2 2.58Å; E237-H240 IonicContact OE2-NE2 3.98Å; E237-H240 PolarHBondContact OE2-NE2 3.23Å; P238-H240 PolarHBondContact O-N 3.26Å; H240-L243 WeakPolarHBondContact O-CB 3.25Å; H240-L243 PolarHBondContact O-N 2.79Å; H240-V244 WeakPolarHBondContact O-CG2 3.42Å; H240-V244 PolarHBondContact O-N 2.98Å
241	S	55.9	Low	64.7	Low	73 Å²	73	39.8 Å²	39.8	51%	0.51	23%	0.225	S	C	.	.	H	α-helix	trans	-65.3	-44.1	-177.2	84.6	0	0	0	0	115.1	L243 V244	S241-L243 PolarHBondContact O-N 3.33Å; S241-V244 WeakPolarHBondContact O-CB 3.12Å; S241-V244 PolarHBondContact O-N 3.49Å
242	P	63.6	Low	65.3	Low	44 Å²	44	45.5 Å²	45.5	29%	0.286	25%	0.25	S	C	.	.	H	α-helix	trans	-73.1	-23.5	178.2	29.8	-35.3	0	0	0	112.7	V14 V244 L245 C246	V14-P242 HydrophobicContact CB-CB 4.12Å; V14-P242 HydrophobicContact CG1-CB 3.16Å; V14-P242 HydrophobicContact CG1-CG 3.23Å; V14-P242 HydrophobicContact CG2-CB 4.48Å; P242-V244 VanDerWaalsContact C-N 3.26Å; P242-V244 PolarHBondContact O-N 3.43Å; P242-L245 PolarHBondContact O-N 3.35Å; P242-C246 PolarHBondContact O-N 3.29Å
243	L	67.6	Low	66.3	Low	23 Å²	23	46.3 Å²	46.3	12%	0.12	25%	0.254	C	S	.	.	H	α-helix	trans	-69.7	-26	177.6	-176.2	65.7	0	0	0	111.7	P211 V215 H240 S241 C246 K247	P211-L243 HydrophobicContact CB-CD1 3.45Å; P211-L243 VanDerWaalsContact CB-CD1 3.45Å; V215-L243 HydrophobicContact CB-CD2 4.24Å; V215-L243 HydrophobicContact CG1-CD2 4.18Å; V215-L243 HydrophobicContact CG2-CD1 4.26Å; V215-L243 HydrophobicContact CG2-CD2 3.18Å; V215-L243 HydrophobicContact CG2-CG 4.36Å; H240-L243 WeakPolarHBondContact O-CB 3.25Å; H240-L243 PolarHBondContact O-N 2.79Å; S241-L243 PolarHBondContact O-N 3.33Å; L243-C246 PolarHBondContact O-N 3.43Å; L243-K247 VanDerWaalsContact O-CG 3.22Å; L243-K247 WeakPolarHBondContact O-CG 3.34Å; L243-K247 PolarHBondContact O-N 3.13Å
244	V	67.5	Low	67.3	Low	22 Å²	22	46 Å²	46	13%	0.133	25%	0.253	C	S	.	.	H	α-helix	trans	-61	-52.9	172.6	176.5	0	0	0	0	111.3	H240 S241 P242 C246 K247 L248 F313	H240-V244 WeakPolarHBondContact O-CG2 3.42Å; H240-V244 PolarHBondContact O-N 2.98Å; S241-V244 WeakPolarHBondContact O-CB 3.12Å; S241-V244 PolarHBondContact O-N 3.49Å; P242-V244 VanDerWaalsContact C-N 3.26Å; P242-V244 PolarHBondContact O-N 3.43Å; V244-C246 PolarHBondContact O-N 3.28Å; V244-K247 PolarHBondContact O-N 2.99Å; V244-K247 VanDerWaalsContact O-N 3.16Å; V244-L248 HydrophobicContact CG1-CD1 4.15Å; V244-L248 PolarHBondContact O-N 2.84Å; V244-F313 HydrophobicContact CB-CE1 3.94Å; V244-F313 HydrophobicContact CB-CE2 4.35Å; V244-F313 HydrophobicContact CB-CZ 3.87Å; V244-F313 HydrophobicContact CG1-CD1 3.72Å; V244-F313 HydrophobicContact CG1-CD2 3.61Å; V244-F313 HydrophobicContact CG1-CE1 3.5Å; V244-F313 VanDerWaalsContact CG1-CE1 3.5Å; V244-F313 HydrophobicContact CG1-CE2 3.42Å; V244-F313 VanDerWaalsContact CG1-CE2 3.42Å; V244-F313 HydrophobicContact CG1-CG 3.83Å; V244-F313 HydrophobicContact CG1-CZ 3.37Å; V244-F313 HydrophobicContact CG2-CD1 4.05Å; V244-F313 HydrophobicContact CG2-CE1 3.17Å; V244-F313 HydrophobicContact CG2-CE2 4.26Å; V244-F313 HydrophobicContact CG2-CZ 3.33Å
245	L	72.8	Confident	68.8	Low	109 Å²	109	46 Å²	46	57%	0.571	25%	0.252	S	S	*	.	H	α-helix	trans	-59.8	-42.1	178.5	-179.2	64.4	0	0	0	110.2	P242 K247 L248 I249	P242-L245 PolarHBondContact O-N 3.35Å; L245-K247 PolarHBondContact O-N 2.91Å; L245-L248 PolarHBondContact O-N 3.18Å; L245-I249 HydrophobicContact CD1-CD1 4.27Å; L245-I249 HydrophobicContact CD1-CG1 4.49Å; L245-I249 HydrophobicContact CG-CD1 3.93Å; L245-I249 WeakPolarHBondContact O-CB 3.32Å; L245-I249 VanDerWaalsContact O-CG1 3.24Å; L245-I249 WeakPolarHBondContact O-CG1 3.41Å; L245-I249 PolarHBondContact O-N 3.17Å
246	C	75.8	Confident	70.3	Confident	14 Å²	14	47.6 Å²	47.6	10%	0.095	26%	0.261	C	S	.	.	H	α-helix	trans	-60.7	-43.6	176.8	-158.9	0	0	0	0	112.1	C11 P242 L243 V244 I249 L250	C11-C246 HydrophobicContact CB-CB 4.32Å; C11-C246 WeakPolarHBondContact CB-SG 3.34Å; C11-C246 VanDerWaalsContact SG-CA 3.55Å; C11-C246 WeakPolarHBondContact SG-CB 3.26Å; C11-C246 CovalentContact SG-SG 2.06Å; C11-C246 PolarHBondContact SG-SG 2.75Å; P242-C246 PolarHBondContact O-N 3.29Å; L243-C246 PolarHBondContact O-N 3.43Å; V244-C246 PolarHBondContact O-N 3.28Å; C246-I249 PolarHBondContact O-N 3.38Å; C246-L250 VanDerWaalsContact O-CG 3.31Å; C246-L250 WeakPolarHBondContact O-CG 3.3Å; C246-L250 PolarHBondContact O-N 3.22Å
247	K	75.8	Confident	72.2	Confident	7 Å²	7	46.4 Å²	46.4	3%	0.03	26%	0.257	C	S	.	.	H	α-helix	trans	-64.9	-43.5	175.7	-69.1	-70.9	-170.9	-167.7	0	112.5	E212 L243 V244 L245 I249 L250 V251 Y309	E212-K247 IonicContact OE1-NZ 2.79Å; E212-K247 PolarHBondContact OE1-NZ 3.35Å; E212-K247 IonicContact OE2-NZ 3.73Å; E212-K247 PolarHBondContact OE2-NZ 2.85Å; L243-K247 VanDerWaalsContact O-CG 3.22Å; L243-K247 WeakPolarHBondContact O-CG 3.34Å; L243-K247 PolarHBondContact O-N 3.13Å; V244-K247 PolarHBondContact O-N 2.99Å; V244-K247 VanDerWaalsContact O-N 3.16Å; L245-K247 PolarHBondContact O-N 2.91Å; K247-I249 VanDerWaalsContact C-N 3.32Å; K247-I249 PolarHBondContact O-N 3.46Å; K247-L250 CarbonylContact O-C 3.56Å; K247-L250 WeakPolarHBondContact O-CB 3.29Å; K247-L250 PolarHBondContact O-N 3.18Å; K247-L250 VanDerWaalsContact O-N 3.13Å; K247-V251 WeakPolarHBondContact O-CG2 3.46Å; K247-V251 PolarHBondContact O-N 2.99Å; K247-Y309 HydrophobicContact CB-CD1 4.29Å; K247-Y309 HydrophobicContact CB-CE1 3.59Å; K247-Y309 HydrophobicContact CG-CE1 4.1Å
248	L	77.4	Confident	74.1	Confident	61 Å²	61	43.5 Å²	43.5	32%	0.319	24%	0.244	S	C	.	.	H	α-helix	trans	-61.5	-41.6	176.2	-77.3	171.1	0	0	0	111.7	V244 L245 L250 V251 F252	V244-L248 HydrophobicContact CG1-CD1 4.15Å; V244-L248 PolarHBondContact O-N 2.84Å; L245-L248 PolarHBondContact O-N 3.18Å; L248-L250 VanDerWaalsContact C-N 3.33Å; L248-L250 PolarHBondContact O-N 2.86Å; L248-V251 PolarHBondContact O-N 2.72Å; L248-F252 WeakPolarHBondContact O-CB 3.44Å; L248-F252 PolarHBondContact O-N 2.88Å
249	I	83.3	Confident	76.3	Confident	55 Å²	55	39.7 Å²	39.7	28%	0.282	22%	0.215	S	C	.	.	H	α-helix	trans	-61.1	-43.5	173.3	-69.6	166.7	0	0	0	110.4	L245 C246 K247 F252 L253	L245-I249 HydrophobicContact CD1-CD1 4.27Å; L245-I249 HydrophobicContact CD1-CG1 4.49Å; L245-I249 HydrophobicContact CG-CD1 3.93Å; L245-I249 WeakPolarHBondContact O-CB 3.32Å; L245-I249 VanDerWaalsContact O-CG1 3.24Å; L245-I249 WeakPolarHBondContact O-CG1 3.41Å; L245-I249 PolarHBondContact O-N 3.17Å; C246-I249 PolarHBondContact O-N 3.38Å; K247-I249 VanDerWaalsContact C-N 3.32Å; K247-I249 PolarHBondContact O-N 3.46Å; I249-F252 PolarHBondContact O-N 3.35Å; I249-L253 VanDerWaalsContact O-CB 3.23Å; I249-L253 WeakPolarHBondContact O-CB 3.39Å; I249-L253 PolarHBondContact O-N 3.16Å
250	L	82.2	Confident	78.3	Confident	17 Å²	17	43.5 Å²	43.5	9%	0.089	23%	0.229	C	C	.	.	H	α-helix	trans	-64.4	-39.5	177.2	-75.7	168.7	0	0	0	112.6	A208 P211 C246 K247 L248 G254	A208-L250 HydrophobicContact CB-CD2 4.01Å; P211-L250 HydrophobicContact CG-CD1 3.59Å; C246-L250 VanDerWaalsContact O-CG 3.31Å; C246-L250 WeakPolarHBondContact O-CG 3.3Å; C246-L250 PolarHBondContact O-N 3.22Å; K247-L250 CarbonylContact O-C 3.56Å; K247-L250 WeakPolarHBondContact O-CB 3.29Å; K247-L250 PolarHBondContact O-N 3.18Å; K247-L250 VanDerWaalsContact O-N 3.13Å; L248-L250 VanDerWaalsContact C-N 3.33Å; L248-L250 PolarHBondContact O-N 2.86Å; L250-G254 VanDerWaalsContact O-CA 3.25Å; L250-G254 WeakPolarHBondContact O-CA 3.25Å; L250-G254 PolarHBondContact O-N 3.4Å
251	V	81.4	Confident	80.2	Confident	4 Å²	4	44.4 Å²	44.4	2%	0.024	24%	0.237	C	C	.	.	H	α-helix	trans	-64.1	-44.7	174.3	172.1	0	0	0	0	110.3	K247 L248 F255 A306	K247-V251 WeakPolarHBondContact O-CG2 3.46Å; K247-V251 PolarHBondContact O-N 2.99Å; L248-V251 PolarHBondContact O-N 2.72Å; V251-F255 WeakPolarHBondContact O-CB 3.22Å; V251-F255 PolarHBondContact O-N 3.48Å; V251-A306 HydrophobicContact CG1-CB 3.91Å
252	F	83.9	Confident	81.9	Confident	122 Å²	122	41 Å²	41	54%	0.535	21%	0.213	S	C	.	.	I	π-helix	trans	-62.3	-49.1	177.4	-174.5	-87.8	0	0	0	111.8	L248 I249 L256 L257	L248-F252 WeakPolarHBondContact O-CB 3.44Å; L248-F252 PolarHBondContact O-N 2.88Å; I249-F252 PolarHBondContact O-N 3.35Å; F252-L256 HydrophobicContact CB-CD1 4.5Å; F252-L256 HydrophobicContact CD2-CB 4.03Å; F252-L256 HydrophobicContact CD2-CD1 3.45Å; F252-L256 VanDerWaalsContact CD2-CD1 3.45Å; F252-L256 HydrophobicContact CD2-CG 4.36Å; F252-L256 HydrophobicContact CE2-CB 4.23Å; F252-L256 HydrophobicContact CE2-CD1 3.97Å; F252-L256 HydrophobicContact CG-CB 4.41Å; F252-L256 HydrophobicContact CG-CD1 4.29Å; F252-L256 WeakPolarHBondContact O-CB 3.33Å; F252-L256 PolarHBondContact O-N 2.8Å; F252-L256 VanDerWaalsContact O-N 3.08Å; F252-L257 PolarHBondContact O-N 3.11Å
253	L	85.8	Confident	83.4	Confident	17 Å²	17	41.7 Å²	41.7	9%	0.089	21%	0.213	C	C	.	.	I	π-helix	trans	-73.3	-32.6	-177.2	-169.3	61.9	0	0	0	112.6	L4 L204 I249 L257 P258	L4-L253 HydrophobicContact CD1-CD1 4.43Å; L4-L253 HydrophobicContact CD2-CD1 4.1Å; L4-L253 HydrophobicContact CD2-CD2 4.21Å; L204-L253 HydrophobicContact CD2-CD2 3.6Å; L204-L253 HydrophobicContact CD2-CG 4.26Å; I249-L253 VanDerWaalsContact O-CB 3.23Å; I249-L253 WeakPolarHBondContact O-CB 3.39Å; I249-L253 PolarHBondContact O-N 3.16Å; L253-L257 HydrophobicContact CD1-CD2 3.6Å; L253-P258 VanDerWaalsContact O-CD 3.28Å; L253-P258 WeakPolarHBondContact O-CD 3.48Å
254	G	84.4	Confident	84.7	Confident	2 Å²	2	47 Å²	47	2%	0.021	23%	0.233	C	C	.	.	I	π-helix	trans	-85.8	-22.4	-176.7	0	0	0	0	0	114.6	A165 L250	A165-G254 WeakPolarHBondContact CB-O 3.33Å; L250-G254 VanDerWaalsContact O-CA 3.25Å; L250-G254 WeakPolarHBondContact O-CA 3.25Å; L250-G254 PolarHBondContact O-N 3.4Å
255	F	84.6	Confident	85.9	Confident	5 Å²	5	46.1 Å²	46.1	2%	0.022	23%	0.227	C	C	.	.	I	π-helix	trans	-128.2	-53.8	179.8	-76.1	-77.9	0	0	0	114.3	V161 Y162 V251 P258 F259 F298	V161-F255 HydrophobicContact CG1-CE1 4.16Å; V161-F255 HydrophobicContact CG1-CE2 4.18Å; V161-F255 HydrophobicContact CG1-CZ 3.38Å; Y162-F255 AromaticContact CD1-CD2 3.83Å; Y162-F255 HydrophobicContact CD1-CD2 3.83Å; Y162-F255 AromaticContact CD1-CE2 3.63Å; Y162-F255 HydrophobicContact CD1-CE2 3.63Å; Y162-F255 HydrophobicContact CD1-CZ 4.43Å; Y162-F255 AromaticContact CE1-CD2 3.53Å; Y162-F255 HydrophobicContact CE1-CD2 3.53Å; Y162-F255 AromaticContact CE1-CE2 3.3Å; Y162-F255 HydrophobicContact CE1-CE2 3.3Å; Y162-F255 HydrophobicContact CE1-CZ 4.4Å; V251-F255 WeakPolarHBondContact O-CB 3.22Å; V251-F255 PolarHBondContact O-N 3.48Å; F255-P258 WeakPolarHBondContact O-CD 3.17Å; F255-F259 VanDerWaalsContact O-CB 3.29Å; F255-F259 WeakPolarHBondContact O-CB 3.36Å; F255-F259 PolarHBondContact O-N 2.82Å; F255-F298 HydrophobicContact CE1-CB 4.42Å; F255-F298 HydrophobicContact CE1-CD1 4.14Å
256	L	85	Confident	86.9	Confident	62 Å²	62	42.2 Å²	42.2	33%	0.325	21%	0.206	S	C	.	.	I	π-helix	trans	-67.6	-41.5	-173.3	-68.5	174.2	0	0	0	112.1	F252 F259 M260	F252-L256 HydrophobicContact CB-CD1 4.5Å; F252-L256 HydrophobicContact CD2-CB 4.03Å; F252-L256 HydrophobicContact CD2-CD1 3.45Å; F252-L256 VanDerWaalsContact CD2-CD1 3.45Å; F252-L256 HydrophobicContact CD2-CG 4.36Å; F252-L256 HydrophobicContact CE2-CB 4.23Å; F252-L256 HydrophobicContact CE2-CD1 3.97Å; F252-L256 HydrophobicContact CG-CB 4.41Å; F252-L256 HydrophobicContact CG-CD1 4.29Å; F252-L256 WeakPolarHBondContact O-CB 3.33Å; F252-L256 PolarHBondContact O-N 2.8Å; F252-L256 VanDerWaalsContact O-N 3.08Å; L256-F259 WeakPolarHBondContact O-CB 3.48Å; L256-F259 PolarHBondContact O-N 3.36Å; L256-M260 VanDerWaalsContact O-CG 3.3Å; L256-M260 WeakPolarHBondContact O-CG 3.4Å; L256-M260 PolarHBondContact O-N 3.06Å
257	L	89.4	Confident	87.8	Confident	83 Å²	83	45.9 Å²	45.9	44%	0.435	23%	0.228	S	C	.	.	H	α-helix	trans	-62.6	-52.6	175.1	177.3	74.5	0	0	0	111.8	F252 L253 F259 M260 V261	F252-L257 PolarHBondContact O-N 3.11Å; L253-L257 HydrophobicContact CD1-CD2 3.6Å; L257-F259 PolarHBondContact O-N 3.23Å; L257-M260 PolarHBondContact O-N 3.37Å; L257-V261 WeakPolarHBondContact O-CG2 3.37Å; L257-V261 PolarHBondContact O-N 3.32Å; L257-V261 VanDerWaalsContact O-N 3.09Å
258	P	91.7	Very high	88.6	Confident	5 Å²	5	46.3 Å²	46.3	3%	0.032	23%	0.233	C	C	.	.	H	α-helix	trans	-51.6	-41.6	171.9	-32.7	37.9	0	0	0	113.7	A165 Q166 A169 L253 F255 V261 C262 F294	A165-P258 HydrophobicContact CB-CB 4.46Å; Q166-P258 HydrophobicContact CG-CG 3.93Å; A169-P258 HydrophobicContact CB-CB 3.82Å; L253-P258 VanDerWaalsContact O-CD 3.28Å; L253-P258 WeakPolarHBondContact O-CD 3.48Å; F255-P258 WeakPolarHBondContact O-CD 3.17Å; P258-V261 PolarHBondContact O-N 3.19Å; P258-C262 WeakPolarHBondContact O-CB 3.5Å; P258-C262 PolarHBondContact O-N 3.46Å; P258-C262 PolarHBondContact O-SG 3.43Å; P258-F294 HydrophobicContact CB-CE2 3.72Å; P258-F294 HydrophobicContact CB-CZ 3.91Å
259	F	90.2	Very high	89.2	Confident	38 Å²	38	43.5 Å²	43.5	17%	0.167	22%	0.218	C	C	.	.	H	α-helix	trans	-61.2	-50.1	179	178	-122.2	0	0	0	112.7	F255 L256 L257 V261 C262 I263 F294 L299	F255-F259 VanDerWaalsContact O-CB 3.29Å; F255-F259 WeakPolarHBondContact O-CB 3.36Å; F255-F259 PolarHBondContact O-N 2.82Å; L256-F259 WeakPolarHBondContact O-CB 3.48Å; L256-F259 PolarHBondContact O-N 3.36Å; L257-F259 PolarHBondContact O-N 3.23Å; F259-V261 VanDerWaalsContact C-N 3.27Å; F259-V261 PolarHBondContact O-N 2.93Å; F259-C262 PolarHBondContact O-N 3.49Å; F259-I263 HydrophobicContact CD1-CD1 4.1Å; F259-I263 HydrophobicContact CD2-CD1 3.92Å; F259-I263 HydrophobicContact CD2-CG1 4.28Å; F259-I263 HydrophobicContact CE1-CD1 3.51Å; F259-I263 HydrophobicContact CE2-CD1 3.32Å; F259-I263 HydrophobicContact CE2-CG1 3.94Å; F259-I263 HydrophobicContact CG-CD1 4.32Å; F259-I263 HydrophobicContact CZ-CD1 3.12Å; F259-I263 HydrophobicContact CZ-CG1 4.22Å; F259-I263 PolarHBondContact O-N 2.86Å; F259-F294 VanDerWaalsContact CA-CE1 3.43Å; F259-F294 VanDerWaalsContact CA-CZ 3.43Å; F259-F294 HydrophobicContact CB-CD1 4.42Å; F259-F294 HydrophobicContact CB-CE1 3.42Å; F259-F294 VanDerWaalsContact CB-CE1 3.42Å; F259-F294 HydrophobicContact CB-CZ 3.7Å; F259-F294 AromaticContact CD2-CD1 3.66Å; F259-F294 HydrophobicContact CD2-CD1 3.66Å; F259-F294 AromaticContact CD2-CE1 3.39Å; F259-F294 HydrophobicContact CD2-CE1 3.39Å; F259-F294 HydrophobicContact CD2-CZ 4.46Å; F259-F294 HydrophobicContact CE2-CD1 4.49Å; F259-F294 HydrophobicContact CE2-CE1 4.49Å; F259-F294 AromaticContact CG-CE1 3.84Å; F259-F294 HydrophobicContact CG-CE1 3.84Å; F259-F294 VanDerWaalsContact N-CZ 3.32Å; F259-L299 HydrophobicContact CD1-CD1 4.24Å; F259-L299 HydrophobicContact CD2-CD1 3.85Å; F259-L299 HydrophobicContact CE1-CD1 4.02Å; F259-L299 HydrophobicContact CE2-CD1 3.59Å; F259-L299 HydrophobicContact CE2-CD2 3.78Å; F259-L299 HydrophobicContact CE2-CG 4.17Å; F259-L299 HydrophobicContact CG-CD1 4.12Å; F259-L299 HydrophobicContact CZ-CD1 3.64Å; F259-L299 HydrophobicContact CZ-CD2 3.89Å; F259-L299 HydrophobicContact CZ-CG 4.4Å
260	M	91.9	Very high	89.6	Confident	128 Å²	128	42.4 Å²	42.4	63%	0.631	21%	0.213	S	C	*	.	H	α-helix	trans	-61.1	-39.6	179.1	-66.7	-58.2	-126.9	0	0	111.3	L256 L257 Y264	L256-M260 VanDerWaalsContact O-CG 3.3Å; L256-M260 WeakPolarHBondContact O-CG 3.4Å; L256-M260 PolarHBondContact O-N 3.06Å; L257-M260 PolarHBondContact O-N 3.37Å; M260-Y264 VanDerWaalsContact O-CB 3.27Å; M260-Y264 WeakPolarHBondContact O-CB 3.44Å; M260-Y264 PolarHBondContact O-N 2.92Å
261	V	93.4	Very high	90	Very high	42 Å²	42	48 Å²	48	26%	0.255	23%	0.234	S	C	.	.	H	α-helix	trans	-63.5	-48.1	174.6	173.8	0	0	0	0	110.7	A169 L173 L257 P258 F259 Y264 T265	A169-V261 HydrophobicContact CB-CB 4.37Å; A169-V261 HydrophobicContact CB-CG1 4.23Å; L173-V261 HydrophobicContact CB-CG1 4.41Å; L257-V261 WeakPolarHBondContact O-CG2 3.37Å; L257-V261 PolarHBondContact O-N 3.32Å; L257-V261 VanDerWaalsContact O-N 3.09Å; P258-V261 PolarHBondContact O-N 3.19Å; F259-V261 VanDerWaalsContact C-N 3.27Å; F259-V261 PolarHBondContact O-N 2.93Å; V261-Y264 PolarHBondContact O-N 3Å; V261-T265 HydrophobicContact CG1-CG2 4.08Å; V261-T265 VanDerWaalsContact O-CB 3.3Å; V261-T265 WeakPolarHBondContact O-CB 3.37Å; V261-T265 WeakPolarHBondContact O-CG2 3.33Å; V261-T265 PolarHBondContact O-N 3.41Å; V261-T265 PolarHBondContact O-OG1 2.96Å
262	C	92.9	Very high	90.3	Very high	1 Å²	1	51.3 Å²	51.3	1%	0.007	25%	0.248	C	C	.	.	H	α-helix	trans	-60.3	-46.7	-180	-73.2	0	0	0	0	112.4	P258 F259 T265 H266 F294	P258-C262 WeakPolarHBondContact O-CB 3.5Å; P258-C262 PolarHBondContact O-N 3.46Å; P258-C262 PolarHBondContact O-SG 3.43Å; F259-C262 PolarHBondContact O-N 3.49Å; C262-T265 PolarHBondContact O-OG1 3.17Å; C262-T265 VanDerWaalsContact O-OG1 3.13Å; C262-H266 WeakPolarHBondContact O-CB 3.39Å; C262-H266 PolarHBondContact O-N 3.19Å; C262-F294 HydrophobicContact CB-CD2 4.32Å; C262-F294 HydrophobicContact CB-CG 4.21Å; C262-F294 VanDerWaalsContact SG-CD2 3.59Å
263	I	93.9	Very high	90.4	Very high	58 Å²	58	46.1 Å²	46.1	30%	0.297	23%	0.226	S	C	.	.	H	α-helix	trans	-61	-54	176.7	-75	172.4	0	0	0	110.6	F259 T265 H266 V267 F291	F259-I263 HydrophobicContact CD1-CD1 4.1Å; F259-I263 HydrophobicContact CD2-CD1 3.92Å; F259-I263 HydrophobicContact CD2-CG1 4.28Å; F259-I263 HydrophobicContact CE1-CD1 3.51Å; F259-I263 HydrophobicContact CE2-CD1 3.32Å; F259-I263 HydrophobicContact CE2-CG1 3.94Å; F259-I263 HydrophobicContact CG-CD1 4.32Å; F259-I263 HydrophobicContact CZ-CD1 3.12Å; F259-I263 HydrophobicContact CZ-CG1 4.22Å; F259-I263 PolarHBondContact O-N 2.86Å; I263-T265 VanDerWaalsContact C-N 3.32Å; I263-T265 PolarHBondContact O-N 3.17Å; I263-H266 PolarHBondContact O-N 3.01Å; I263-V267 HydrophobicContact CG2-CG2 4.34Å; I263-V267 WeakPolarHBondContact O-CG2 3.41Å; I263-V267 PolarHBondContact O-N 3.37Å; I263-F291 HydrophobicContact CG1-CE2 3.64Å; I263-F291 HydrophobicContact CG1-CZ 4.29Å
264	Y	95.1	Very high	90.4	Very high	135 Å²	135	52.6 Å²	52.6	53%	0.529	26%	0.256	S	S	.	.	H	α-helix	trans	-58.4	-47.5	-175.9	171.6	-95.6	0	0	0	111.2	Y176 M260 V261 A268	Y176-Y264 HydrophobicContact CD2-CE1 4.36Å; Y176-Y264 AromaticContact CE2-CE1 3.79Å; Y176-Y264 HydrophobicContact CE2-CE1 3.79Å; Y176-Y264 AromaticContact CZ-CE1 3.93Å; Y176-Y264 PolarHBondContact OH-OH 2.94Å; M260-Y264 VanDerWaalsContact O-CB 3.27Å; M260-Y264 WeakPolarHBondContact O-CB 3.44Å; M260-Y264 PolarHBondContact O-N 2.92Å; V261-Y264 PolarHBondContact O-N 3Å; Y264-A268 VanDerWaalsContact O-CB 3.25Å; Y264-A268 WeakPolarHBondContact O-CB 3.36Å; Y264-A268 PolarHBondContact O-N 2.86Å
265	T	93.8	Very high	90.4	Very high	3 Å²	3	58 Å²	58	2%	0.018	28%	0.281	C	S	.	.	H	α-helix	trans	-66.9	-38.9	-179.5	54.7	0	0	0	0	111.9	S172 L173 Y176 V261 C262 I263 V269	S172-T265 VanDerWaalsContact CB-OG1 3.31Å; S172-T265 WeakPolarHBondContact CB-OG1 3.24Å; L173-T265 HydrophobicContact CD1-CG2 4.35Å; Y176-T265 HydrophobicContact CD2-CG2 4.43Å; Y176-T265 HydrophobicContact CG-CG2 4.01Å; V261-T265 HydrophobicContact CG1-CG2 4.08Å; V261-T265 VanDerWaalsContact O-CB 3.3Å; V261-T265 WeakPolarHBondContact O-CB 3.37Å; V261-T265 WeakPolarHBondContact O-CG2 3.33Å; V261-T265 PolarHBondContact O-N 3.41Å; V261-T265 PolarHBondContact O-OG1 2.96Å; C262-T265 PolarHBondContact O-OG1 3.17Å; C262-T265 VanDerWaalsContact O-OG1 3.13Å; I263-T265 VanDerWaalsContact C-N 3.32Å; I263-T265 PolarHBondContact O-N 3.17Å; T265-V269 VanDerWaalsContact O-CB 3.31Å; T265-V269 WeakPolarHBondContact O-CB 3.19Å; T265-V269 WeakPolarHBondContact O-CG2 3.39Å; T265-V269 PolarHBondContact O-N 3.2Å
266	H	93.2	Very high	90.1	Very high	27 Å²	27	59.9 Å²	59.9	13%	0.125	29%	0.294	C	S	.	.	H	α-helix	trans	-62.6	-53.8	176.1	-179.5	55	0	0	0	111.6	C262 I263 A268 V269 I270 S287 F291	C262-H266 WeakPolarHBondContact O-CB 3.39Å; C262-H266 PolarHBondContact O-N 3.19Å; I263-H266 PolarHBondContact O-N 3.01Å; H266-A268 VanDerWaalsContact C-N 3.32Å; H266-A268 PolarHBondContact O-N 3.2Å; H266-V269 PolarHBondContact O-N 3.31Å; H266-I270 WeakPolarHBondContact O-CG1 3.26Å; H266-I270 PolarHBondContact O-N 2.95Å; H266-S287 PolarHBondContact ND1-OG 3.01Å; H266-F291 HydrophobicContact CB-CB 4.18Å; H266-F291 HydrophobicContact CB-CD2 4.12Å; H266-F291 HydrophobicContact CB-CG 4.14Å; H266-F291 AromaticContact CD2-CD1 3.39Å; H266-F291 WeakPolarHBondContact CD2-CD1 3.11Å; H266-F291 AromaticContact CD2-CE1 3.89Å; H266-F291 AromaticContact CD2-CG 3.48Å; H266-F291 VanDerWaalsContact CD2-CG 3.48Å; H266-F291 WeakPolarHBondContact CD2-CG 3.31Å; H266-F291 AromaticContact CG-CG 3.72Å; H266-F291 AromaticContact NE2-CD1 3.6Å; H266-F291 AromaticContact NE2-CG 3.99Å
267	V	94.1	Very high	89.6	Confident	92 Å²	92	62.3 Å²	62.3	56%	0.558	32%	0.317	S	S	*	.	H	α-helix	trans	-57.5	-46.4	179.5	173.2	0	0	0	0	110.9	I263 V269 I270 Y271	I263-V267 HydrophobicContact CG2-CG2 4.34Å; I263-V267 WeakPolarHBondContact O-CG2 3.41Å; I263-V267 PolarHBondContact O-N 3.37Å; V267-V269 PolarHBondContact O-N 3.37Å; V267-I270 PolarHBondContact O-N 2.88Å; V267-Y271 VanDerWaalsContact O-CB 3.31Å; V267-Y271 WeakPolarHBondContact O-CB 3.42Å; V267-Y271 PolarHBondContact O-N 3.27Å
268	A	93.1	Very high	89	Confident	15 Å²	15	59.7 Å²	59.7	12%	0.124	31%	0.305	C	S	.	.	H	α-helix	trans	-64.5	-39.8	179.2	0	0	0	0	0	112.7	Y176 V180 Y264 H266 H272	Y176-A268 HydrophobicContact CD2-CB 3.81Å; Y176-A268 HydrophobicContact CE2-CB 3.74Å; V180-A268 HydrophobicContact CG2-CB 4.27Å; Y264-A268 VanDerWaalsContact O-CB 3.25Å; Y264-A268 WeakPolarHBondContact O-CB 3.36Å; Y264-A268 PolarHBondContact O-N 2.86Å; H266-A268 VanDerWaalsContact C-N 3.32Å; H266-A268 PolarHBondContact O-N 3.2Å; A268-H272 WeakPolarHBondContact O-CB 2.97Å; A268-H272 PolarHBondContact O-CD2 3.13Å; A268-H272 VanDerWaalsContact O-CD2 3.27Å; A268-H272 PolarHBondContact O-N 3.5Å; A268-H272 VanDerWaalsContact O-N 3.13Å
269	V	89.9	Confident	88.4	Confident	3 Å²	3	64.7 Å²	64.7	2%	0.018	33%	0.331	C	S	.	.	H	α-helix	trans	-63.6	-50.2	176.2	166.4	0	0	0	0	110.4	V179 T265 H266 V267 Y271 H272 L273	V179-V269 HydrophobicContact CB-CG2 4.37Å; V179-V269 HydrophobicContact CG2-CG1 4.38Å; T265-V269 VanDerWaalsContact O-CB 3.31Å; T265-V269 WeakPolarHBondContact O-CB 3.19Å; T265-V269 WeakPolarHBondContact O-CG2 3.39Å; T265-V269 PolarHBondContact O-N 3.2Å; H266-V269 PolarHBondContact O-N 3.31Å; V267-V269 PolarHBondContact O-N 3.37Å; V269-Y271 PolarHBondContact O-N 3.38Å; V269-H272 PolarHBondContact O-N 2.91Å; V269-L273 HydrophobicContact CG1-CD1 3.66Å; V269-L273 HydrophobicContact CG1-CG 4.19Å; V269-L273 WeakPolarHBondContact O-CB 3.42Å; V269-L273 VanDerWaalsContact O-CG 3.22Å; V269-L273 WeakPolarHBondContact O-CG 3.25Å; V269-L273 PolarHBondContact O-N 3.45Å
270	I	91.2	Very high	88	Confident	32 Å²	32	64.2 Å²	64.2	16%	0.164	33%	0.328	C	S	.	.	H	α-helix	trans	-59.6	-50.3	-179.4	-62.9	-57.5	0	0	0	111	H266 V267 H272 L273 E274 T284	H266-I270 WeakPolarHBondContact O-CG1 3.26Å; H266-I270 PolarHBondContact O-N 2.95Å; V267-I270 PolarHBondContact O-N 2.88Å; I270-H272 VanDerWaalsContact C-N 3.31Å; I270-H272 PolarHBondContact O-N 3.28Å; I270-L273 PolarHBondContact O-N 2.85Å; I270-L273 VanDerWaalsContact O-N 3.12Å; I270-E274 HydrophobicContact CG2-CG 4.33Å; I270-E274 WeakPolarHBondContact O-CG 3.24Å; I270-E274 PolarHBondContact O-N 3.06Å; I270-T284 HydrophobicContact CD1-CG2 3.66Å
271	Y	91.9	Very high	87.6	Confident	135 Å²	135	64 Å²	64	53%	0.529	32%	0.324	S	S	.	.	H	α-helix	trans	-54.7	-44.6	178.7	177.2	-100	0	0	0	112.8	V267 V269 Q275	V267-Y271 VanDerWaalsContact O-CB 3.31Å; V267-Y271 WeakPolarHBondContact O-CB 3.42Å; V267-Y271 PolarHBondContact O-N 3.27Å; V269-Y271 PolarHBondContact O-N 3.38Å; Y271-Q275 VanDerWaalsContact CE1-NE2 3.26Å; Y271-Q275 WeakPolarHBondContact O-CG 3.45Å; Y271-Q275 PolarHBondContact O-N 3.35Å; Y271-Q275 PolarHBondContact OH-NE2 2.97Å
272	H	87.1	Confident	87.1	Confident	73 Å²	73	63.9 Å²	63.9	34%	0.338	32%	0.322	S	S	.	.	H	α-helix	trans	-72.4	-33	179.1	-87.8	-73	0	0	0	113.7	V179 V180 A268 V269 I270	V179-H272 HydrophobicContact CG1-CB 4.04Å; V180-H272 HydrophobicContact CG2-CB 4.34Å; A268-H272 WeakPolarHBondContact O-CB 2.97Å; A268-H272 PolarHBondContact O-CD2 3.13Å; A268-H272 VanDerWaalsContact O-CD2 3.27Å; A268-H272 PolarHBondContact O-N 3.5Å; A268-H272 VanDerWaalsContact O-N 3.13Å; V269-H272 PolarHBondContact O-N 2.91Å; I270-H272 VanDerWaalsContact C-N 3.31Å; I270-H272 PolarHBondContact O-N 3.28Å
273	L	85.9	Confident	86.6	Confident	12 Å²	12	64.1 Å²	64.1	6%	0.063	32%	0.323	C	S	.	.	H	α-helix	trans	-71.6	-38.1	177.9	-67.4	178.8	0	0	0	111.5	V179 V269 I270 Q275 S276 W280 F283 T284	V179-L273 HydrophobicContact CG1-CD2 3.67Å; V179-L273 HydrophobicContact CG1-CG 4Å; V179-L273 HydrophobicContact CG2-CD2 4.27Å; V269-L273 HydrophobicContact CG1-CD1 3.66Å; V269-L273 HydrophobicContact CG1-CG 4.19Å; V269-L273 WeakPolarHBondContact O-CB 3.42Å; V269-L273 VanDerWaalsContact O-CG 3.22Å; V269-L273 WeakPolarHBondContact O-CG 3.25Å; V269-L273 PolarHBondContact O-N 3.45Å; I270-L273 PolarHBondContact O-N 2.85Å; I270-L273 VanDerWaalsContact O-N 3.12Å; L273-Q275 VanDerWaalsContact C-N 3.28Å; L273-Q275 PolarHBondContact O-N 3.4Å; L273-S276 PolarHBondContact O-N 3.17Å; L273-S276 PolarHBondContact O-OG 2.93Å; L273-W280 HydrophobicContact CB-CB 4.35Å; L273-W280 HydrophobicContact CD1-CB 4.19Å; L273-W280 HydrophobicContact CD2-CB 3.74Å; L273-W280 HydrophobicContact CD2-CD2 4.13Å; L273-W280 HydrophobicContact CD2-CG 3.59Å; L273-W280 HydrophobicContact CG-CB 4.3Å; L273-F283 HydrophobicContact CD1-CB 3.83Å; L273-T284 WeakPolarHBondContact CD1-OG1 3.44Å
274	E	86.4	Confident	86.2	Confident	153 Å²	153	63.6 Å²	63.6	72%	0.715	32%	0.322	S	S	*	.	H	α-helix	trans	-64.5	-30.2	177.3	-73.8	-177.7	166.6	0	0	113.4	I270 S276	I270-E274 HydrophobicContact CG2-CG 4.33Å; I270-E274 WeakPolarHBondContact O-CG 3.24Å; I270-E274 PolarHBondContact O-N 3.06Å; E274-S276 PolarHBondContact O-N 2.73Å
275	Q	83.4	Confident	85.9	Confident	117 Å²	117	65.2 Å²	65.2	55%	0.547	33%	0.327	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.8	-10.7	177.1	-71.5	-176.2	-0.4	0	0	114.2	Y271 L273	Y271-Q275 VanDerWaalsContact CE1-NE2 3.26Å; Y271-Q275 WeakPolarHBondContact O-CG 3.45Å; Y271-Q275 PolarHBondContact O-N 3.35Å; Y271-Q275 PolarHBondContact OH-NE2 2.97Å; L273-Q275 VanDerWaalsContact C-N 3.28Å; L273-Q275 PolarHBondContact O-N 3.4Å
276	S	79.6	Confident	85.5	Confident	43 Å²	43	65 Å²	65	30%	0.301	33%	0.326	S	S	.	.	S	Bend	trans	-98.9	145.4	-174	73	0	0	0	0	111.7	L273 E274 C278 W280	L273-S276 PolarHBondContact O-N 3.17Å; L273-S276 PolarHBondContact O-OG 2.93Å; E274-S276 PolarHBondContact O-N 2.73Å; S276-C278 VanDerWaalsContact C-N 3.31Å; S276-C278 PolarHBondContact O-N 3.38Å; S276-W280 PolarHBondContact OG-NE1 3.19Å
277	S	73.3	Confident	85.3	Confident	114 Å²	114	64.4 Å²	64.4	80%	0.797	33%	0.325	S	S	*	.	S	Bend	trans	-84	0.7	-177.1	-42.5	0	0	0	0	114.3
278	C	76.8	Confident	85.1	Confident	28 Å²	28	62.2 Å²	62.2	19%	0.189	31%	0.312	C	S	.	.	S	Bend	trans	-94.7	154.6	179.6	-42.9	0	0	0	0	110.7	S276 W280 C358	S276-C278 VanDerWaalsContact C-N 3.31Å; S276-C278 PolarHBondContact O-N 3.38Å; C278-W280 HydrophobicContact CB-CH2 4.29Å; C278-W280 HydrophobicContact CB-CZ2 3.51Å; C278-W280 PolarHBondContact O-N 3Å; C278-C358 HydrophobicContact CB-CB 4.38Å; C278-C358 WeakPolarHBondContact CB-SG 3.24Å; C278-C358 WeakPolarHBondContact SG-CB 3.05Å; C278-C358 CovalentContact SG-SG 2.08Å; C278-C358 PolarHBondContact SG-SG 2.95Å
279	D	78.6	Confident	84.9	Confident	109 Å²	109	63.5 Å²	63.5	58%	0.583	32%	0.316	S	S	*	.			trans	-77	105.3	176.3	-169.3	-15.6	0	0	0	111.4	K281	D279-K281 WeakPolarHBondContact OD1-CB 3.23Å; D279-K281 VanDerWaalsContact OD1-CD 3.24Å; D279-K281 WeakPolarHBondContact OD1-CD 3.3Å; D279-K281 WeakPolarHBondContact OD1-CG 3.08Å; D279-K281 PolarHBondContact OD1-N 3.08Å; D279-K281 IonicContact OD1-NZ 3.85Å; D279-K281 WeakPolarHBondContact OD2-CE 3.36Å; D279-K281 IonicContact OD2-NZ 2.85Å; D279-K281 PolarHBondContact OD2-NZ 3.08Å
280	W	82.1	Confident	84.9	Confident	28 Å²	28	63.6 Å²	63.6	11%	0.106	32%	0.317	C	S	.	.			trans	-106.6	20.4	179	-58.5	110.8	0	0	0	114.6	L273 S276 C278 L282 F283 T284 F355 C358	L273-W280 HydrophobicContact CB-CB 4.35Å; L273-W280 HydrophobicContact CD1-CB 4.19Å; L273-W280 HydrophobicContact CD2-CB 3.74Å; L273-W280 HydrophobicContact CD2-CD2 4.13Å; L273-W280 HydrophobicContact CD2-CG 3.59Å; L273-W280 HydrophobicContact CG-CB 4.3Å; S276-W280 PolarHBondContact OG-NE1 3.19Å; C278-W280 HydrophobicContact CB-CH2 4.29Å; C278-W280 HydrophobicContact CB-CZ2 3.51Å; C278-W280 PolarHBondContact O-N 3Å; W280-L282 PolarHBondContact O-N 3.35Å; W280-F283 HydrophobicContact CB-CB 4.36Å; W280-F283 AromaticContact CE3-CD2 3.91Å; W280-F283 HydrophobicContact CE3-CD2 3.91Å; W280-F283 HydrophobicContact CE3-CE2 4.2Å; W280-F283 HydrophobicContact CE3-CG 4.33Å; W280-F283 HydrophobicContact CZ3-CE2 4.36Å; W280-F283 PolarHBondContact O-N 3.12Å; W280-T284 PolarHBondContact O-N 3.23Å; W280-T284 PolarHBondContact O-OG1 3.12Å; W280-F355 HydrophobicContact CE3-CD2 4.23Å; W280-F355 HydrophobicContact CH2-CB 3.72Å; W280-F355 AromaticContact CH2-CD2 3.2Å; W280-F355 HydrophobicContact CH2-CD2 3.2Å; W280-F355 HydrophobicContact CH2-CE2 4.12Å; W280-F355 AromaticContact CH2-CG 3.84Å; W280-F355 HydrophobicContact CH2-CG 3.84Å; W280-F355 AromaticContact CZ2-CD2 3.49Å; W280-F355 HydrophobicContact CZ2-CD2 3.49Å; W280-F355 VanDerWaalsContact CZ2-CD2 3.49Å; W280-F355 AromaticContact CZ2-CE2 3.95Å; W280-F355 HydrophobicContact CZ2-CE2 3.95Å; W280-F355 HydrophobicContact CZ2-CG 4.44Å; W280-F355 HydrophobicContact CZ3-CB 3.87Å; W280-F355 AromaticContact CZ3-CD2 3.55Å; W280-F355 HydrophobicContact CZ3-CD2 3.55Å; W280-F355 HydrophobicContact CZ3-CG 4.19Å; W280-C358 HydrophobicContact CH2-CB 4.47Å
281	K	83	Confident	85	Confident	124 Å²	124	64.2 Å²	64.2	54%	0.539	32%	0.318	S	S	.	.	H	α-helix	trans	-47.9	-38.7	-177	-79.1	165.2	-164.5	149.5	0	113.6	D279 R285	D279-K281 WeakPolarHBondContact OD1-CB 3.23Å; D279-K281 VanDerWaalsContact OD1-CD 3.24Å; D279-K281 WeakPolarHBondContact OD1-CD 3.3Å; D279-K281 WeakPolarHBondContact OD1-CG 3.08Å; D279-K281 PolarHBondContact OD1-N 3.08Å; D279-K281 IonicContact OD1-NZ 3.85Å; D279-K281 WeakPolarHBondContact OD2-CE 3.36Å; D279-K281 IonicContact OD2-NZ 2.85Å; D279-K281 PolarHBondContact OD2-NZ 3.08Å; K281-R285 WeakPolarHBondContact O-CB 3.31Å; K281-R285 WeakPolarHBondContact O-CG 2.92Å; K281-R285 PolarHBondContact O-N 2.83Å
282	L	82.9	Confident	85	Confident	40 Å²	40	61.6 Å²	61.6	21%	0.209	31%	0.313	C	S	.	.	H	α-helix	trans	-67.3	-42.9	178.5	-174	67	0	0	0	112.5	W280 R285 V286 L344 L347 T348	W280-L282 PolarHBondContact O-N 3.35Å; L282-R285 PolarHBondContact O-N 3.26Å; L282-V286 WeakPolarHBondContact O-CG2 3.43Å; L282-V286 PolarHBondContact O-N 3.37Å; L282-L344 HydrophobicContact CD1-CD2 3.96Å; L282-L347 HydrophobicContact CD2-CB 3.69Å; L282-T348 HydrophobicContact CD2-CG2 3.72Å; L282-T348 HydrophobicContact CG-CG2 3.68Å
283	F	82.6	Confident	85.2	Confident	6 Å²	6	58.2 Å²	58.2	3%	0.026	30%	0.297	C	S	.	.	H	α-helix	trans	-64.8	-42.3	177.5	-82	-115.7	0	0	0	111.2	R175 V179 L273 W280 V286 S287 T348 E352	R175-F283 VanDerWaalsContact CZ-CE1 3.48Å; V179-F283 HydrophobicContact CG2-CD1 3.87Å; V179-F283 HydrophobicContact CG2-CE1 4.41Å; L273-F283 HydrophobicContact CD1-CB 3.83Å; W280-F283 HydrophobicContact CB-CB 4.36Å; W280-F283 AromaticContact CE3-CD2 3.91Å; W280-F283 HydrophobicContact CE3-CD2 3.91Å; W280-F283 HydrophobicContact CE3-CE2 4.2Å; W280-F283 HydrophobicContact CE3-CG 4.33Å; W280-F283 HydrophobicContact CZ3-CE2 4.36Å; W280-F283 PolarHBondContact O-N 3.12Å; F283-V286 PolarHBondContact O-N 2.98Å; F283-S287 PolarHBondContact O-N 3.01Å; F283-T348 HydrophobicContact CD2-CG2 4.24Å; F283-T348 HydrophobicContact CE2-CG2 4.26Å; F283-E352 HydrophobicContact CZ-CG 4.36Å
284	T	85.9	Confident	85.4	Confident	47 Å²	47	57.7 Å²	57.7	29%	0.288	30%	0.295	S	S	.	.	H	α-helix	trans	-59.5	-51.6	173.3	-60.5	0	0	0	0	110.7	I270 L273 W280 V286 S287 T288	I270-T284 HydrophobicContact CD1-CG2 3.66Å; L273-T284 WeakPolarHBondContact CD1-OG1 3.44Å; W280-T284 PolarHBondContact O-N 3.23Å; W280-T284 PolarHBondContact O-OG1 3.12Å; T284-V286 VanDerWaalsContact C-N 3.31Å; T284-V286 PolarHBondContact O-N 2.79Å; T284-S287 PolarHBondContact O-N 3.07Å; T284-S287 VanDerWaalsContact O-N 3.16Å; T284-T288 WeakPolarHBondContact O-CB 3.49Å; T284-T288 PolarHBondContact O-N 2.82Å; T284-T288 PolarHBondContact O-OG1 3Å
285	R	88.2	Confident	85.7	Confident	168 Å²	168	54 Å²	54	63%	0.634	28%	0.279	S	S	*	.	H	α-helix	trans	-55.1	-44.1	177.7	-78.3	174.4	-177.2	-174.6	1.1	112.7	K281 L282 L289	K281-R285 WeakPolarHBondContact O-CB 3.31Å; K281-R285 WeakPolarHBondContact O-CG 2.92Å; K281-R285 PolarHBondContact O-N 2.83Å; L282-R285 PolarHBondContact O-N 3.26Å; R285-L289 VanDerWaalsContact O-CB 3.23Å; R285-L289 WeakPolarHBondContact O-CB 3.41Å; R285-L289 PolarHBondContact O-N 2.88Å
286	V	86.9	Confident	86.1	Confident	0 Å²	0	51.6 Å²	51.6	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-65.2	-48	178	179.3	0	0	0	0	110.9	L282 F283 T284 T288 L289 V290 L341 L344 L345 T348	L282-V286 WeakPolarHBondContact O-CG2 3.43Å; L282-V286 PolarHBondContact O-N 3.37Å; F283-V286 PolarHBondContact O-N 2.98Å; T284-V286 VanDerWaalsContact C-N 3.31Å; T284-V286 PolarHBondContact O-N 2.79Å; V286-T288 PolarHBondContact O-N 3.32Å; V286-L289 PolarHBondContact O-N 3.48Å; V286-V290 HydrophobicContact CG1-CG2 4.45Å; V286-V290 VanDerWaalsContact O-CG2 3.26Å; V286-V290 WeakPolarHBondContact O-CG2 3.22Å; V286-V290 PolarHBondContact O-N 3.38Å; V286-L341 HydrophobicContact CG1-CD1 4.39Å; V286-L344 HydrophobicContact CG2-CB 3.67Å; V286-L345 HydrophobicContact CG1-CD2 4.11Å; V286-L345 HydrophobicContact CG1-CG 4.29Å; V286-T348 HydrophobicContact CG2-CG2 3.64Å
287	S	88.4	Confident	86.7	Confident	13 Å²	13	49.8 Å²	49.8	9%	0.091	26%	0.26	C	S	.	.	H	α-helix	trans	-62.7	-43.6	179.8	-176.8	0	0	0	0	111.9	H266 F283 T284 V290 F291	H266-S287 PolarHBondContact ND1-OG 3.01Å; F283-S287 PolarHBondContact O-N 3.01Å; T284-S287 PolarHBondContact O-N 3.07Å; T284-S287 VanDerWaalsContact O-N 3.16Å; S287-V290 PolarHBondContact O-N 3.38Å; S287-F291 WeakPolarHBondContact O-CB 3.3Å; S287-F291 PolarHBondContact O-N 3.45Å
288	T	89.9	Confident	87.6	Confident	46 Å²	46	44.3 Å²	44.3	28%	0.282	22%	0.222	S	C	.	.	H	α-helix	trans	-64.6	-42.2	176.2	-56.5	0	0	0	0	111.5	T284 V286 F291 I292	T284-T288 WeakPolarHBondContact O-CB 3.49Å; T284-T288 PolarHBondContact O-N 2.82Å; T284-T288 PolarHBondContact O-OG1 3Å; V286-T288 PolarHBondContact O-N 3.32Å; T288-F291 PolarHBondContact O-N 2.91Å; T288-I292 HydrophobicContact CG2-CD1 3.78Å; T288-I292 HydrophobicContact CG2-CG1 4.33Å; T288-I292 WeakPolarHBondContact O-CB 3.5Å; T288-I292 VanDerWaalsContact O-CG1 3.25Å; T288-I292 WeakPolarHBondContact O-CG1 3.31Å; T288-I292 PolarHBondContact O-N 3.28Å
289	L	90	Very high	88.2	Confident	42 Å²	42	44.9 Å²	44.9	22%	0.22	22%	0.223	C	C	.	.	H	α-helix	trans	-61.1	-48.7	176.5	178.4	65.3	0	0	0	111.2	R285 V286 F291 I292 I293 F340 L344	R285-L289 VanDerWaalsContact O-CB 3.23Å; R285-L289 WeakPolarHBondContact O-CB 3.41Å; R285-L289 PolarHBondContact O-N 2.88Å; V286-L289 PolarHBondContact O-N 3.48Å; L289-F291 VanDerWaalsContact C-N 3.27Å; L289-F291 PolarHBondContact O-N 2.91Å; L289-I292 PolarHBondContact O-N 3.46Å; L289-I293 HydrophobicContact CD1-CD1 4.24Å; L289-I293 HydrophobicContact CD1-CG1 4.33Å; L289-I293 HydrophobicContact CG-CD1 3.94Å; L289-I293 HydrophobicContact CG-CG1 4.44Å; L289-I293 VanDerWaalsContact O-CG1 3.28Å; L289-I293 WeakPolarHBondContact O-CG1 2.97Å; L289-I293 PolarHBondContact O-N 3.4Å; L289-F340 HydrophobicContact CD2-CB 4.44Å; L289-L344 HydrophobicContact CD2-CD1 3.53Å
290	V	89.9	Confident	88.9	Confident	5 Å²	5	41.7 Å²	41.7	3%	0.03	21%	0.208	C	C	.	.	H	α-helix	trans	-59	-42.4	178.3	176.6	0	0	0	0	111.1	I168 I171 S172 V286 S287 I293 F294 L341	I168-V290 HydrophobicContact CG2-CG1 3.63Å; I171-V290 HydrophobicContact CG2-CG2 4.41Å; S172-V290 WeakPolarHBondContact OG-CG1 3.35Å; V286-V290 HydrophobicContact CG1-CG2 4.45Å; V286-V290 VanDerWaalsContact O-CG2 3.26Å; V286-V290 WeakPolarHBondContact O-CG2 3.22Å; V286-V290 PolarHBondContact O-N 3.38Å; S287-V290 PolarHBondContact O-N 3.38Å; V290-I293 PolarHBondContact O-N 2.73Å; V290-F294 PolarHBondContact O-N 3.45Å; V290-L341 HydrophobicContact CG2-CD1 3.32Å; V290-L341 HydrophobicContact CG2-CD2 4.44Å
291	F	91.6	Very high	89.3	Confident	45 Å²	45	40.4 Å²	40.4	20%	0.197	20%	0.203	C	C	.	.	H	α-helix	trans	-64.5	-43.5	176.4	-179.2	-115.8	0	0	0	112.5	I263 H266 S287 T288 L289 F294 L295	I263-F291 HydrophobicContact CG1-CE2 3.64Å; I263-F291 HydrophobicContact CG1-CZ 4.29Å; H266-F291 HydrophobicContact CB-CB 4.18Å; H266-F291 HydrophobicContact CB-CD2 4.12Å; H266-F291 HydrophobicContact CB-CG 4.14Å; H266-F291 AromaticContact CD2-CD1 3.39Å; H266-F291 WeakPolarHBondContact CD2-CD1 3.11Å; H266-F291 AromaticContact CD2-CE1 3.89Å; H266-F291 AromaticContact CD2-CG 3.48Å; H266-F291 VanDerWaalsContact CD2-CG 3.48Å; H266-F291 WeakPolarHBondContact CD2-CG 3.31Å; H266-F291 AromaticContact CG-CG 3.72Å; H266-F291 AromaticContact NE2-CD1 3.6Å; H266-F291 AromaticContact NE2-CG 3.99Å; S287-F291 WeakPolarHBondContact O-CB 3.3Å; S287-F291 PolarHBondContact O-N 3.45Å; T288-F291 PolarHBondContact O-N 2.91Å; L289-F291 VanDerWaalsContact C-N 3.27Å; L289-F291 PolarHBondContact O-N 2.91Å; F291-F294 PolarHBondContact O-N 2.96Å; F291-L295 HydrophobicContact CE1-CD2 4.47Å; F291-L295 WeakPolarHBondContact O-CB 3.43Å; F291-L295 PolarHBondContact O-N 3.39Å
292	I	91.8	Very high	89.6	Confident	81 Å²	81	34.7 Å²	34.7	42%	0.415	18%	0.179	S	C	.	.	H	α-helix	trans	-62.4	-44.7	176.2	-72	169.5	0	0	0	110.9	T288 L289 F294 L295 V296	T288-I292 HydrophobicContact CG2-CD1 3.78Å; T288-I292 HydrophobicContact CG2-CG1 4.33Å; T288-I292 WeakPolarHBondContact O-CB 3.5Å; T288-I292 VanDerWaalsContact O-CG1 3.25Å; T288-I292 WeakPolarHBondContact O-CG1 3.31Å; T288-I292 PolarHBondContact O-N 3.28Å; L289-I292 PolarHBondContact O-N 3.46Å; I292-F294 VanDerWaalsContact C-N 3.26Å; I292-F294 PolarHBondContact O-N 2.87Å; I292-L295 PolarHBondContact O-N 3.4Å; I292-V296 HydrophobicContact CG2-CG2 4.09Å; I292-V296 WeakPolarHBondContact O-CB 3.47Å; I292-V296 WeakPolarHBondContact O-CG2 3.41Å; I292-V296 PolarHBondContact O-N 2.76Å
293	I	91.6	Very high	89.9	Confident	2 Å²	2	36.4 Å²	36.4	1%	0.01	19%	0.191	C	C	.	.	H	α-helix	trans	-56.2	-46.5	175.7	-68.1	167.9	0	0	0	109.5	I168 L289 V290 C297 F298 H334 L337	I168-I293 HydrophobicContact CD1-CG2 3.86Å; L289-I293 HydrophobicContact CD1-CD1 4.24Å; L289-I293 HydrophobicContact CD1-CG1 4.33Å; L289-I293 HydrophobicContact CG-CD1 3.94Å; L289-I293 HydrophobicContact CG-CG1 4.44Å; L289-I293 VanDerWaalsContact O-CG1 3.28Å; L289-I293 WeakPolarHBondContact O-CG1 2.97Å; L289-I293 PolarHBondContact O-N 3.4Å; V290-I293 PolarHBondContact O-N 2.73Å; I293-C297 WeakPolarHBondContact O-CA 3.49Å; I293-C297 WeakPolarHBondContact O-CB 3.3Å; I293-C297 PolarHBondContact O-N 2.99Å; I293-F298 HydrophobicContact CG2-CD2 4.3Å; I293-F298 HydrophobicContact CG2-CE2 3.92Å; I293-H334 HydrophobicContact CG2-CB 4.16Å; I293-L337 HydrophobicContact CD1-CB 3.89Å; I293-L337 HydrophobicContact CD1-CD1 4.38Å; I293-L337 HydrophobicContact CG1-CB 4.2Å; I293-L337 HydrophobicContact CG1-CD1 3.75Å
294	F	90.8	Very high	90.2	Very high	1 Å²	1	38.2 Å²	38.2	0%	0.004	20%	0.201	C	C	.	.	I	π-helix	trans	-62.8	-46.7	177.9	-159.5	-76.1	0	0	0	112.1	A165 I168 P258 F259 C262 V290 F291 I292 F298 L299	A165-F294 HydrophobicContact CB-CE2 4.37Å; I168-F294 HydrophobicContact CG2-CD2 3.91Å; P258-F294 HydrophobicContact CB-CE2 3.72Å; P258-F294 HydrophobicContact CB-CZ 3.91Å; F259-F294 VanDerWaalsContact CA-CE1 3.43Å; F259-F294 VanDerWaalsContact CA-CZ 3.43Å; F259-F294 HydrophobicContact CB-CD1 4.42Å; F259-F294 HydrophobicContact CB-CE1 3.42Å; F259-F294 VanDerWaalsContact CB-CE1 3.42Å; F259-F294 HydrophobicContact CB-CZ 3.7Å; F259-F294 AromaticContact CD2-CD1 3.66Å; F259-F294 HydrophobicContact CD2-CD1 3.66Å; F259-F294 AromaticContact CD2-CE1 3.39Å; F259-F294 HydrophobicContact CD2-CE1 3.39Å; F259-F294 HydrophobicContact CD2-CZ 4.46Å; F259-F294 HydrophobicContact CE2-CD1 4.49Å; F259-F294 HydrophobicContact CE2-CE1 4.49Å; F259-F294 AromaticContact CG-CE1 3.84Å; F259-F294 HydrophobicContact CG-CE1 3.84Å; F259-F294 VanDerWaalsContact N-CZ 3.32Å; C262-F294 HydrophobicContact CB-CD2 4.32Å; C262-F294 HydrophobicContact CB-CG 4.21Å; C262-F294 VanDerWaalsContact SG-CD2 3.59Å; V290-F294 PolarHBondContact O-N 3.45Å; F291-F294 PolarHBondContact O-N 2.96Å; I292-F294 VanDerWaalsContact C-N 3.26Å; I292-F294 PolarHBondContact O-N 2.87Å; F294-F298 HydrophobicContact CD1-CB 4.31Å; F294-F298 HydrophobicContact CD2-CB 4.24Å; F294-F298 HydrophobicContact CD2-CG 4.47Å; F294-F298 HydrophobicContact CE1-CB 4.22Å; F294-F298 HydrophobicContact CE2-CB 4.21Å; F294-F298 HydrophobicContact CG-CB 4.3Å; F294-F298 HydrophobicContact CZ-CB 4.2Å; F294-F298 WeakPolarHBondContact O-CB 3.4Å; F294-F298 PolarHBondContact O-N 3.08Å; F294-F298 VanDerWaalsContact O-N 3.08Å; F294-L299 PolarHBondContact O-N 3.35Å
295	L	92.1	Very high	90.3	Very high	74 Å²	74	36.2 Å²	36.2	39%	0.387	19%	0.188	S	C	.	.	I	π-helix	trans	-65.2	-39.7	-176.9	-174	69.8	0	0	0	112.8	F291 I292 L299 P300	F291-L295 HydrophobicContact CE1-CD2 4.47Å; F291-L295 WeakPolarHBondContact O-CB 3.43Å; F291-L295 PolarHBondContact O-N 3.39Å; I292-L295 PolarHBondContact O-N 3.4Å; L295-L299 HydrophobicContact CD1-CD2 3.63Å; L295-P300 WeakPolarHBondContact O-CD 3.44Å
296	V	92.1	Very high	90.1	Very high	68 Å²	68	29.1 Å²	29.1	41%	0.412	17%	0.165	S	C	.	.	I	π-helix	trans	-89.9	-45.8	-175	177.4	0	0	0	0	111.2	I292 P300 L330	I292-V296 HydrophobicContact CG2-CG2 4.09Å; I292-V296 WeakPolarHBondContact O-CB 3.47Å; I292-V296 WeakPolarHBondContact O-CG2 3.41Å; I292-V296 PolarHBondContact O-N 2.76Å; V296-P300 WeakPolarHBondContact O-CD 3.24Å; V296-P300 WeakPolarHBondContact O-CG 3.21Å; V296-L330 HydrophobicContact CG1-CD1 4.42Å; V296-L330 HydrophobicContact CG1-CD2 4.42Å; V296-L330 WeakPolarHBondContact O-CD2 3.41Å; V296-L330 WeakPolarHBondContact O-CG 3.02Å
297	C	92.1	Very high	90.1	Very high	4 Å²	4	30.6 Å²	30.6	3%	0.027	18%	0.178	C	C	.	.	I	π-helix	trans	-87.1	-45	-174.2	-60.6	0	0	0	0	112.4	I293 C331 H334	I293-C297 WeakPolarHBondContact O-CA 3.49Å; I293-C297 WeakPolarHBondContact O-CB 3.3Å; I293-C297 PolarHBondContact O-N 2.99Å; C297-C331 WeakPolarHBondContact O-CA 3.47Å; C297-C331 VanDerWaalsContact O-CB 3.25Å; C297-C331 WeakPolarHBondContact O-CB 3.39Å; C297-C331 PolarHBondContact O-N 3.03Å; C297-H334 HydrophobicContact CB-CB 4.22Å
298	F	91.7	Very high	89.9	Confident	0 Å²	0	30 Å²	30	0%	0	17%	0.174	C	C	.	.	I	π-helix	trans	-96	-42.3	-168.1	-68.5	-89.7	0	0	0	113.7	A165 I168 F255 I293 F294 S301 G302 C331 H334	A165-F298 HydrophobicContact CB-CD1 3.63Å; A165-F298 HydrophobicContact CB-CE1 3.83Å; A165-F298 HydrophobicContact CB-CG 4.44Å; I168-F298 HydrophobicContact CD1-CD2 4.07Å; I168-F298 HydrophobicContact CD1-CE2 3.22Å; I168-F298 HydrophobicContact CD1-CZ 3.61Å; F255-F298 HydrophobicContact CE1-CB 4.42Å; F255-F298 HydrophobicContact CE1-CD1 4.14Å; I293-F298 HydrophobicContact CG2-CD2 4.3Å; I293-F298 HydrophobicContact CG2-CE2 3.92Å; F294-F298 HydrophobicContact CD1-CB 4.31Å; F294-F298 HydrophobicContact CD2-CB 4.24Å; F294-F298 HydrophobicContact CD2-CG 4.47Å; F294-F298 HydrophobicContact CE1-CB 4.22Å; F294-F298 HydrophobicContact CE2-CB 4.21Å; F294-F298 HydrophobicContact CG-CB 4.3Å; F294-F298 HydrophobicContact CZ-CB 4.2Å; F294-F298 WeakPolarHBondContact O-CB 3.4Å; F294-F298 PolarHBondContact O-N 3.08Å; F294-F298 VanDerWaalsContact O-N 3.08Å; F298-S301 PolarHBondContact O-N 3.41Å; F298-G302 PolarHBondContact O-N 3.47Å; F298-C331 VanDerWaalsContact CD1-SG 3.52Å; F298-H334 HydrophobicContact CE2-CB 3.44Å; F298-H334 VanDerWaalsContact CE2-CB 3.44Å; F298-H334 AromaticContact CE2-CG 3.75Å; F298-H334 HydrophobicContact CZ-CB 3.61Å; F298-H334 AromaticContact CZ-CD2 3.75Å; F298-H334 AromaticContact CZ-CG 3.34Å; F298-H334 AromaticContact CZ-ND1 3.57Å
299	L	90.9	Very high	89.2	Confident	40 Å²	40	28.4 Å²	28.4	21%	0.209	16%	0.162	C	C	.	.	H	α-helix	trans	-59.6	-46	-175.4	-178.4	66.3	0	0	0	113	F259 F294 L295 S301 G302 V303	F259-L299 HydrophobicContact CD1-CD1 4.24Å; F259-L299 HydrophobicContact CD2-CD1 3.85Å; F259-L299 HydrophobicContact CE1-CD1 4.02Å; F259-L299 HydrophobicContact CE2-CD1 3.59Å; F259-L299 HydrophobicContact CE2-CD2 3.78Å; F259-L299 HydrophobicContact CE2-CG 4.17Å; F259-L299 HydrophobicContact CG-CD1 4.12Å; F259-L299 HydrophobicContact CZ-CD1 3.64Å; F259-L299 HydrophobicContact CZ-CD2 3.89Å; F259-L299 HydrophobicContact CZ-CG 4.4Å; F294-L299 PolarHBondContact O-N 3.35Å; L295-L299 HydrophobicContact CD1-CD2 3.63Å; L299-S301 VanDerWaalsContact C-N 3.31Å; L299-S301 PolarHBondContact O-N 3.23Å; L299-G302 PolarHBondContact O-N 3.25Å; L299-V303 HydrophobicContact CD1-CG2 3.65Å; L299-V303 HydrophobicContact CG-CG2 4.09Å; L299-V303 WeakPolarHBondContact O-CB 3.33Å; L299-V303 WeakPolarHBondContact O-CG2 3.38Å; L299-V303 PolarHBondContact O-N 3.43Å
300	P	92.2	Very high	88.8	Confident	42 Å²	42	31.3 Å²	31.3	27%	0.273	18%	0.177	S	C	.	.	H	α-helix	trans	-61.8	-42.8	-179.1	-23.6	36.5	0	0	0	111.3	L295 V296 L304 A327 L330	L295-P300 WeakPolarHBondContact O-CD 3.44Å; V296-P300 WeakPolarHBondContact O-CD 3.24Å; V296-P300 WeakPolarHBondContact O-CG 3.21Å; P300-L304 VanDerWaalsContact O-CB 3.26Å; P300-L304 WeakPolarHBondContact O-CB 3.42Å; P300-L304 WeakPolarHBondContact O-CG 3.48Å; P300-L304 PolarHBondContact O-N 3.33Å; P300-A327 HydrophobicContact CB-CB 4.14Å; P300-L330 HydrophobicContact CG-CD2 4.39Å
301	S	90.8	Very high	88.3	Confident	1 Å²	1	36.9 Å²	36.9	1%	0.007	20%	0.198	C	C	.	.	H	α-helix	trans	-60.9	-50.4	176.4	-179.3	0	0	0	0	111	F298 L299 V303 L304 H305 V328	F298-S301 PolarHBondContact O-N 3.41Å; L299-S301 VanDerWaalsContact C-N 3.31Å; L299-S301 PolarHBondContact O-N 3.23Å; S301-V303 PolarHBondContact O-N 3.28Å; S301-L304 PolarHBondContact O-N 3.29Å; S301-H305 WeakPolarHBondContact O-CB 3.06Å; S301-H305 PolarHBondContact O-N 3.17Å; S301-V328 WeakPolarHBondContact OG-CG2 3.33Å
302	G	88.6	Confident	87.4	Confident	4 Å²	4	34.7 Å²	34.7	4%	0.041	19%	0.188	C	C	.	.	H	α-helix	trans	-61.7	-44.4	-180	0	0	0	0	0	113.7	F298 L299 A306	F298-G302 PolarHBondContact O-N 3.47Å; L299-G302 PolarHBondContact O-N 3.25Å; G302-A306 WeakPolarHBondContact O-CB 3.5Å; G302-A306 PolarHBondContact O-N 2.93Å
303	V	89.5	Confident	86.4	Confident	75 Å²	75	32.9 Å²	32.9	46%	0.455	18%	0.177	S	C	.	.	H	α-helix	trans	-67.1	-48.1	179.2	172.1	0	0	0	0	111	L299 S301 H305 A306 A307	L299-V303 HydrophobicContact CD1-CG2 3.65Å; L299-V303 HydrophobicContact CG-CG2 4.09Å; L299-V303 WeakPolarHBondContact O-CB 3.33Å; L299-V303 WeakPolarHBondContact O-CG2 3.38Å; L299-V303 PolarHBondContact O-N 3.43Å; S301-V303 PolarHBondContact O-N 3.28Å; V303-H305 VanDerWaalsContact C-N 3.31Å; V303-H305 PolarHBondContact O-N 3.01Å; V303-A306 PolarHBondContact O-N 3.25Å; V303-A307 VanDerWaalsContact O-CB 3.25Å; V303-A307 WeakPolarHBondContact O-CB 3.49Å; V303-A307 PolarHBondContact O-N 3.07Å
304	L	90.3	Very high	85.5	Confident	44 Å²	44	37.8 Å²	37.8	23%	0.23	21%	0.212	C	C	.	.	H	α-helix	trans	-67.1	-35.3	179.5	-75	164.7	0	0	0	111.7	P300 S301 H308 A327	P300-L304 VanDerWaalsContact O-CB 3.26Å; P300-L304 WeakPolarHBondContact O-CB 3.42Å; P300-L304 WeakPolarHBondContact O-CG 3.48Å; P300-L304 PolarHBondContact O-N 3.33Å; S301-L304 PolarHBondContact O-N 3.29Å; L304-H308 WeakPolarHBondContact O-CB 3.08Å; L304-H308 PolarHBondContact O-N 3.09Å; L304-A327 HydrophobicContact CD1-CB 3.51Å
305	H	86.4	Confident	84.6	Confident	6 Å²	6	41.7 Å²	41.7	3%	0.028	24%	0.239	C	C	.	.	H	α-helix	trans	-64.1	-47.9	175	-165.6	-179.4	0	0	0	111.1	Y162 S301 V303 Y309 Y324	Y162-H305 PolarHBondContact OH-CE1 3.46Å; S301-H305 WeakPolarHBondContact O-CB 3.06Å; S301-H305 PolarHBondContact O-N 3.17Å; V303-H305 VanDerWaalsContact C-N 3.31Å; V303-H305 PolarHBondContact O-N 3.01Å; H305-Y309 AromaticContact CD2-CD2 3.36Å; H305-Y309 WeakPolarHBondContact CD2-CD2 3.47Å; H305-Y309 AromaticContact CD2-CE2 3.3Å; H305-Y309 WeakPolarHBondContact CD2-CE2 3.31Å; H305-Y309 AromaticContact NE2-CD2 3.65Å; H305-Y309 AromaticContact NE2-CE2 3.08Å; H305-Y309 WeakPolarHBondContact NE2-CE2 3.25Å; H305-Y309 AromaticContact NE2-CZ 3.8Å; H305-Y309 WeakPolarHBondContact O-CB 3.28Å; H305-Y309 WeakPolarHBondContact O-CD2 3.31Å; H305-Y309 PolarHBondContact O-N 2.74Å; H305-Y324 HydrophobicContact CB-CD2 3.72Å; H305-Y324 HydrophobicContact CB-CE2 3.56Å; H305-Y324 AromaticContact CD2-CE2 3.63Å; H305-Y324 AromaticContact CD2-CZ 3.86Å; H305-Y324 AromaticContact CG-CE2 3.45Å; H305-Y324 VanDerWaalsContact CG-CE2 3.45Å; H305-Y324 AromaticContact ND1-CE2 3.85Å
306	A	84.8	Confident	83.4	Confident	18 Å²	18	39.5 Å²	39.5	15%	0.149	23%	0.234	C	C	.	.	H	α-helix	trans	-62.4	-47.1	176.1	0	0	0	0	0	111.8	V251 G302 V303 Y309 I310	V251-A306 HydrophobicContact CG1-CB 3.91Å; G302-A306 WeakPolarHBondContact O-CB 3.5Å; G302-A306 PolarHBondContact O-N 2.93Å; V303-A306 PolarHBondContact O-N 3.25Å; A306-Y309 PolarHBondContact O-N 2.73Å; A306-I310 WeakPolarHBondContact O-CB 3.19Å; A306-I310 WeakPolarHBondContact O-CD1 3.44Å; A306-I310 WeakPolarHBondContact O-CG1 3.26Å; A306-I310 PolarHBondContact O-N 3.3Å
307	A	86.5	Confident	82.5	Confident	32 Å²	32	38 Å²	38	26%	0.264	22%	0.224	S	C	.	.	H	α-helix	trans	-63.8	-43.7	179.9	0	0	0	0	0	112	V303 I310 R311 L320	V303-A307 VanDerWaalsContact O-CB 3.25Å; V303-A307 WeakPolarHBondContact O-CB 3.49Å; V303-A307 PolarHBondContact O-N 3.07Å; A307-I310 PolarHBondContact O-N 3.44Å; A307-R311 WeakPolarHBondContact O-CB 3.46Å; A307-R311 WeakPolarHBondContact O-CG 3.33Å; A307-R311 PolarHBondContact O-N 3.46Å; A307-L320 HydrophobicContact CB-CD1 3.98Å
308	H	83.6	Confident	81.6	Confident	1 Å²	1	38.6 Å²	38.6	1%	0.005	23%	0.227	C	C	.	.	H	α-helix	trans	-59.9	-49.7	175.3	175.6	59.1	0	0	0	110.4	L304 I310 R311 L312 L320 Y321	L304-H308 WeakPolarHBondContact O-CB 3.08Å; L304-H308 PolarHBondContact O-N 3.09Å; H308-I310 PolarHBondContact O-N 2.94Å; H308-R311 PolarHBondContact O-N 3.34Å; H308-L312 WeakPolarHBondContact O-CB 3.42Å; H308-L312 PolarHBondContact O-N 3.03Å; H308-L320 HydrophobicContact CB-CB 4.09Å; H308-Y321 AromaticContact CE1-CD2 3.95Å; H308-Y321 AromaticContact NE2-CD2 3.52Å
309	Y	76.9	Confident	81.1	Confident	11 Å²	11	42.6 Å²	42.6	4%	0.043	25%	0.251	C	S	.	.	H	α-helix	trans	-57.7	-49.7	176.6	-93.2	-114.7	0	0	0	111.4	K247 H305 A306 R311 L312 F313	K247-Y309 HydrophobicContact CB-CD1 4.29Å; K247-Y309 HydrophobicContact CB-CE1 3.59Å; K247-Y309 HydrophobicContact CG-CE1 4.1Å; H305-Y309 AromaticContact CD2-CD2 3.36Å; H305-Y309 WeakPolarHBondContact CD2-CD2 3.47Å; H305-Y309 AromaticContact CD2-CE2 3.3Å; H305-Y309 WeakPolarHBondContact CD2-CE2 3.31Å; H305-Y309 AromaticContact NE2-CD2 3.65Å; H305-Y309 AromaticContact NE2-CE2 3.08Å; H305-Y309 WeakPolarHBondContact NE2-CE2 3.25Å; H305-Y309 AromaticContact NE2-CZ 3.8Å; H305-Y309 WeakPolarHBondContact O-CB 3.28Å; H305-Y309 WeakPolarHBondContact O-CD2 3.31Å; H305-Y309 PolarHBondContact O-N 2.74Å; A306-Y309 PolarHBondContact O-N 2.73Å; Y309-R311 PolarHBondContact O-N 2.92Å; Y309-L312 PolarHBondContact O-N 3.27Å; Y309-F313 HydrophobicContact CD1-CD2 4.33Å; Y309-F313 AromaticContact CD1-CE2 3.56Å; Y309-F313 HydrophobicContact CD1-CE2 3.56Å; Y309-F313 HydrophobicContact CE1-CE2 4.13Å; Y309-F313 HydrophobicContact CG-CE2 4.25Å; Y309-F313 WeakPolarHBondContact O-CD2 3.4Å; Y309-F313 PolarHBondContact O-N 2.79Å
310	I	80.6	Confident	80.7	Confident	104 Å²	104	42.2 Å²	42.2	53%	0.533	25%	0.249	S	C	.	.	H	α-helix	trans	-58.4	-45.9	-179.4	-68.6	163.9	0	0	0	111.6	A306 A307 H308 F313 S314	A306-I310 WeakPolarHBondContact O-CB 3.19Å; A306-I310 WeakPolarHBondContact O-CD1 3.44Å; A306-I310 WeakPolarHBondContact O-CG1 3.26Å; A306-I310 PolarHBondContact O-N 3.3Å; A307-I310 PolarHBondContact O-N 3.44Å; H308-I310 PolarHBondContact O-N 2.94Å; I310-F313 PolarHBondContact O-N 3.23Å; I310-S314 VanDerWaalsContact O-CB 3.25Å; I310-S314 WeakPolarHBondContact O-CB 3.21Å; I310-S314 PolarHBondContact O-N 3.34Å
311	R	79.9	Confident	80.2	Confident	121 Å²	121	40.3 Å²	40.3	46%	0.457	24%	0.237	S	C	.	.	H	α-helix	trans	-66.4	-43	178.2	-75.6	-167.8	176.8	-131.7	-1.4	112.6	A307 H308 Y309 F313 S314 S315 G316 D317 L320	A307-R311 WeakPolarHBondContact O-CB 3.46Å; A307-R311 WeakPolarHBondContact O-CG 3.33Å; A307-R311 PolarHBondContact O-N 3.46Å; H308-R311 PolarHBondContact O-N 3.34Å; Y309-R311 PolarHBondContact O-N 2.92Å; R311-F313 PolarHBondContact O-N 2.96Å; R311-S314 PolarHBondContact O-N 3.15Å; R311-S315 PolarHBondContact O-N 2.96Å; R311-S315 PolarHBondContact O-OG 2.92Å; R311-G316 PolarHBondContact O-N 3.37Å; R311-D317 HydrophobicContact CB-CB 4.41Å; R311-D317 IonicContact NH1-OD2 2.72Å; R311-D317 PolarHBondContact NH1-OD2 3.44Å; R311-L320 HydrophobicContact CG-CD1 4.45Å
312	L	73	Confident	79.9	Confident	0 Å²	0	40.9 Å²	40.9	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-60.6	-37.6	178.5	-162.7	64.8	0	0	0	111	P29 P30 H308 Y309 G316 D318	P29-L312 WeakPolarHBondContact CB-O 3.22Å; P30-L312 HydrophobicContact CB-CD1 4.29Å; P30-L312 HydrophobicContact CB-CD2 4.35Å; P30-L312 HydrophobicContact CB-CG 4.27Å; P30-L312 HydrophobicContact CG-CD1 3.7Å; P30-L312 HydrophobicContact CG-CG 3.94Å; P30-L312 WeakPolarHBondContact O-CD2 3.09Å; P30-L312 VanDerWaalsContact O-CG 3.23Å; P30-L312 WeakPolarHBondContact O-CG 3.05Å; H308-L312 WeakPolarHBondContact O-CB 3.42Å; H308-L312 PolarHBondContact O-N 3.03Å; Y309-L312 PolarHBondContact O-N 3.27Å; L312-G316 VanDerWaalsContact O-CA 3.26Å; L312-G316 WeakPolarHBondContact O-CA 3.41Å; L312-G316 PolarHBondContact O-N 3.42Å; L312-D318 HydrophobicContact CD1-CB 3.9Å
313	F	70.2	Confident	79.9	Confident	43 Å²	43	48 Å²	48	19%	0.189	27%	0.269	C	S	.	.	H	α-helix	trans	-80.4	-33.1	176.2	-73.4	-61.7	0	0	0	114.7	P29 P30 K31 V244 Y309 I310 R311	P29-F313 HydrophobicContact CB-CD1 4.3Å; P29-F313 HydrophobicContact CG-CD1 4.06Å; P29-F313 WeakPolarHBondContact CG-O 3.42Å; P29-F313 WeakPolarHBondContact O-CE1 3.19Å; P30-F313 WeakPolarHBondContact O-CE1 3.37Å; P30-F313 WeakPolarHBondContact O-CZ 3.42Å; K31-F313 HydrophobicContact CG-CZ 3.9Å; V244-F313 HydrophobicContact CB-CE1 3.94Å; V244-F313 HydrophobicContact CB-CE2 4.35Å; V244-F313 HydrophobicContact CB-CZ 3.87Å; V244-F313 HydrophobicContact CG1-CD1 3.72Å; V244-F313 HydrophobicContact CG1-CD2 3.61Å; V244-F313 HydrophobicContact CG1-CE1 3.5Å; V244-F313 VanDerWaalsContact CG1-CE1 3.5Å; V244-F313 HydrophobicContact CG1-CE2 3.42Å; V244-F313 VanDerWaalsContact CG1-CE2 3.42Å; V244-F313 HydrophobicContact CG1-CG 3.83Å; V244-F313 HydrophobicContact CG1-CZ 3.37Å; V244-F313 HydrophobicContact CG2-CD1 4.05Å; V244-F313 HydrophobicContact CG2-CE1 3.17Å; V244-F313 HydrophobicContact CG2-CE2 4.26Å; V244-F313 HydrophobicContact CG2-CZ 3.33Å; Y309-F313 HydrophobicContact CD1-CD2 4.33Å; Y309-F313 AromaticContact CD1-CE2 3.56Å; Y309-F313 HydrophobicContact CD1-CE2 3.56Å; Y309-F313 HydrophobicContact CE1-CE2 4.13Å; Y309-F313 HydrophobicContact CG-CE2 4.25Å; Y309-F313 WeakPolarHBondContact O-CD2 3.4Å; Y309-F313 PolarHBondContact O-N 2.79Å; I310-F313 PolarHBondContact O-N 3.23Å; R311-F313 PolarHBondContact O-N 2.96Å
314	S	72.9	Confident	79.8	Confident	105 Å²	105	44.6 Å²	44.6	73%	0.734	25%	0.249	S	C	*	.	H	α-helix	trans	-83.5	-42.1	-176.4	-172.8	0	0	0	0	112.8	I310 R311	I310-S314 VanDerWaalsContact O-CB 3.25Å; I310-S314 WeakPolarHBondContact O-CB 3.21Å; I310-S314 PolarHBondContact O-N 3.34Å; R311-S314 PolarHBondContact O-N 3.15Å
315	S	72.2	Confident	79.7	Confident	82 Å²	82	42.6 Å²	42.6	57%	0.573	24%	0.238	S	C	*	.	H	α-helix	trans	-127.1	-5.5	-170.2	54.2	0	0	0	0	113.4	R311 D317	R311-S315 PolarHBondContact O-N 2.96Å; R311-S315 PolarHBondContact O-OG 2.92Å; S315-D317 PolarHBondContact O-N 3.16Å; S315-D317 WeakPolarHBondContact OG-CB 3.45Å
316	G	67.1	Low	80	Confident	28 Å²	28	45 Å²	45	29%	0.289	25%	0.251	S	S	.	.			trans	68.4	18	-173.8	0	0	0	0	0	113.3	R311 L312	R311-G316 PolarHBondContact O-N 3.37Å; L312-G316 VanDerWaalsContact O-CA 3.26Å; L312-G316 WeakPolarHBondContact O-CA 3.41Å; L312-G316 PolarHBondContact O-N 3.42Å
317	D	73	Confident	80.4	Confident	37 Å²	37	44.4 Å²	44.4	20%	0.198	25%	0.246	C	C	.	.			trans	-84.6	119.6	-178.3	173.6	15.3	0	0	0	110.4	R311 S315 T319	R311-D317 HydrophobicContact CB-CB 4.41Å; R311-D317 IonicContact NH1-OD2 2.72Å; R311-D317 PolarHBondContact NH1-OD2 3.44Å; S315-D317 PolarHBondContact O-N 3.16Å; S315-D317 WeakPolarHBondContact OG-CB 3.45Å; D317-T319 VanDerWaalsContact OD1-CB 3.27Å; D317-T319 WeakPolarHBondContact OD1-CB 3.2Å; D317-T319 WeakPolarHBondContact OD1-CG2 3.38Å; D317-T319 PolarHBondContact OD1-N 3.37Å; D317-T319 PolarHBondContact OD1-OG1 2.06Å; D317-T319 PolarHBondContact OD2-OG1 2.95Å
318	D	73.4	Confident	80.6	Confident	16 Å²	16	43 Å²	43	9%	0.086	23%	0.234	C	C	.	.			trans	-107.5	6.9	-178.3	57.7	5.5	0	0	0	113.8	F33 P65 L312 L320 Y321	F33-D318 HydrophobicContact CD1-CB 4.2Å; F33-D318 VanDerWaalsContact CD1-OD2 3.24Å; F33-D318 WeakPolarHBondContact CD1-OD2 3.29Å; P65-D318 WeakPolarHBondContact CG-OD1 3.22Å; L312-D318 HydrophobicContact CD1-CB 3.9Å; D318-L320 PolarHBondContact O-N 2.79Å; D318-Y321 VanDerWaalsContact O-CB 3.25Å; D318-Y321 WeakPolarHBondContact O-CB 3.32Å; D318-Y321 PolarHBondContact O-N 3.4Å
319	T	79.6	Confident	81.1	Confident	84 Å²	84	43.2 Å²	43.2	52%	0.515	24%	0.236	S	C	.	.	T	Hydrogen-bonded Turn	trans	-56.3	-29.1	-178.6	54.6	0	0	0	0	114.1	D317 Y321	D317-T319 VanDerWaalsContact OD1-CB 3.27Å; D317-T319 WeakPolarHBondContact OD1-CB 3.2Å; D317-T319 WeakPolarHBondContact OD1-CG2 3.38Å; D317-T319 PolarHBondContact OD1-N 3.37Å; D317-T319 PolarHBondContact OD1-OG1 2.06Å; D317-T319 PolarHBondContact OD2-OG1 2.95Å; T319-Y321 VanDerWaalsContact C-N 3.29Å; T319-Y321 PolarHBondContact O-N 2.9Å
320	L	83.7	Confident	81.9	Confident	32 Å²	32	46 Å²	46	17%	0.168	25%	0.251	C	S	.	.	T	Hydrogen-bonded Turn	trans	-77	-10.3	178.9	-68.1	-174.9	0	0	0	114.3	A307 H308 R311 D318 G322 Y323 Y324	A307-L320 HydrophobicContact CB-CD1 3.98Å; H308-L320 HydrophobicContact CB-CB 4.09Å; R311-L320 HydrophobicContact CG-CD1 4.45Å; D318-L320 PolarHBondContact O-N 2.79Å; L320-G322 PolarHBondContact O-N 3.04Å; L320-Y323 HydrophobicContact CD2-CD2 4.36Å; L320-Y323 PolarHBondContact O-N 2.85Å; L320-Y324 WeakPolarHBondContact O-CB 3.49Å; L320-Y324 PolarHBondContact O-N 3.02Å
321	Y	82.1	Confident	82.5	Confident	2 Å²	2	41 Å²	41	1%	0.008	23%	0.225	C	C	.	.	H	α-helix	trans	-60.1	-46.1	-173.1	-176.2	-97.5	0	0	0	112.4	F33 Y69 D231 H308 D318 T319 Y323 Y324 R325	F33-Y321 AromaticContact CD2-CD1 3.92Å; F33-Y321 HydrophobicContact CD2-CD1 3.92Å; F33-Y321 HydrophobicContact CD2-CE1 4.04Å; F33-Y321 HydrophobicContact CD2-CG 4.44Å; F33-Y321 HydrophobicContact CE1-CD1 4.49Å; F33-Y321 AromaticContact CE2-CD1 3.12Å; F33-Y321 HydrophobicContact CE2-CD1 3.12Å; F33-Y321 AromaticContact CE2-CE1 3.46Å; F33-Y321 HydrophobicContact CE2-CE1 3.46Å; F33-Y321 VanDerWaalsContact CE2-CE1 3.46Å; F33-Y321 AromaticContact CE2-CG 3.91Å; F33-Y321 HydrophobicContact CE2-CG 3.91Å; F33-Y321 AromaticContact CZ-CD1 3.47Å; F33-Y321 HydrophobicContact CZ-CD1 3.47Å; F33-Y321 VanDerWaalsContact CZ-CD1 3.47Å; F33-Y321 HydrophobicContact CZ-CE1 4.25Å; F33-Y321 HydrophobicContact CZ-CG 4.05Å; Y69-Y321 HydrophobicContact CD1-CD1 4.49Å; Y69-Y321 HydrophobicContact CD1-CE1 4.17Å; Y69-Y321 HydrophobicContact CD2-CD1 4.28Å; Y69-Y321 HydrophobicContact CE1-CD1 4.36Å; Y69-Y321 AromaticContact CE1-CE1 3.71Å; Y69-Y321 HydrophobicContact CE1-CE1 3.71Å; Y69-Y321 HydrophobicContact CE2-CD1 4.12Å; Y69-Y321 HydrophobicContact CE2-CE1 4.1Å; Y69-Y321 HydrophobicContact CG-CD1 4.46Å; Y69-Y321 AromaticContact CZ-CE1 3.66Å; D231-Y321 PolarHBondContact OD1-OH 2.87Å; D231-Y321 VanDerWaalsContact OD1-OH 3.12Å; H308-Y321 AromaticContact CE1-CD2 3.95Å; H308-Y321 AromaticContact NE2-CD2 3.52Å; D318-Y321 VanDerWaalsContact O-CB 3.25Å; D318-Y321 WeakPolarHBondContact O-CB 3.32Å; D318-Y321 PolarHBondContact O-N 3.4Å; T319-Y321 VanDerWaalsContact C-N 3.29Å; T319-Y321 PolarHBondContact O-N 2.9Å; Y321-Y323 PolarHBondContact O-N 2.79Å; Y321-Y324 HydrophobicContact CD2-CD1 4.15Å; Y321-Y324 HydrophobicContact CE2-CD1 4.26Å; Y321-Y324 HydrophobicContact CE2-CE1 4.28Å; Y321-Y324 WeakPolarHBondContact O-CB 3.25Å; Y321-Y324 PolarHBondContact O-N 3.26Å; Y321-R325 HydrophobicContact CD1-CG 4.02Å; Y321-R325 HydrophobicContact CE1-CG 3.62Å; Y321-R325 HydrophobicContact CE2-CG 4.39Å; Y321-R325 WeakPolarHBondContact O-CG 3.43Å; Y321-R325 PolarHBondContact O-N 2.58Å; Y321-R325 PolarHBondContact OH-NH1 3.25Å
322	G	83	Confident	83.1	Confident	13 Å²	13	35.2 Å²	35.2	13%	0.134	20%	0.203	C	C	.	.	H	α-helix	trans	-59.7	-44.5	178.4	0	0	0	0	0	112.6	L320 R325 L326	L320-G322 PolarHBondContact O-N 3.04Å; G322-R325 PolarHBondContact O-N 3.41Å; G322-L326 WeakPolarHBondContact O-CG 2.97Å; G322-L326 PolarHBondContact O-N 3.27Å
323	Y	88.2	Confident	84	Confident	153 Å²	153	37.8 Å²	37.8	60%	0.6	21%	0.214	S	C	*	.	H	α-helix	trans	-63.7	-43.1	176.6	-63.5	-78.7	0	0	0	112.2	L320 Y321 R325 L326 A327	L320-Y323 HydrophobicContact CD2-CD2 4.36Å; L320-Y323 PolarHBondContact O-N 2.85Å; Y321-Y323 PolarHBondContact O-N 2.79Å; Y323-R325 VanDerWaalsContact C-N 3.31Å; Y323-R325 PolarHBondContact O-N 2.82Å; Y323-L326 PolarHBondContact O-N 2.88Å; Y323-A327 WeakPolarHBondContact O-CB 3.16Å; Y323-A327 PolarHBondContact O-N 3.22Å
324	Y	88.5	Confident	85.1	Confident	5 Å²	5	35.7 Å²	35.7	2%	0.02	21%	0.206	C	C	.	.	H	α-helix	trans	-56.9	-45	173.3	154.6	-108.8	0	0	0	111.4	F158 H305 L320 Y321 L326 A327 V328	F158-Y324 WeakPolarHBondContact CE1-OH 3.23Å; F158-Y324 WeakPolarHBondContact CZ-OH 3.44Å; H305-Y324 HydrophobicContact CB-CD2 3.72Å; H305-Y324 HydrophobicContact CB-CE2 3.56Å; H305-Y324 AromaticContact CD2-CE2 3.63Å; H305-Y324 AromaticContact CD2-CZ 3.86Å; H305-Y324 AromaticContact CG-CE2 3.45Å; H305-Y324 VanDerWaalsContact CG-CE2 3.45Å; H305-Y324 AromaticContact ND1-CE2 3.85Å; L320-Y324 WeakPolarHBondContact O-CB 3.49Å; L320-Y324 PolarHBondContact O-N 3.02Å; Y321-Y324 HydrophobicContact CD2-CD1 4.15Å; Y321-Y324 HydrophobicContact CE2-CD1 4.26Å; Y321-Y324 HydrophobicContact CE2-CE1 4.28Å; Y321-Y324 WeakPolarHBondContact O-CB 3.25Å; Y321-Y324 PolarHBondContact O-N 3.26Å; Y324-L326 PolarHBondContact O-N 3.38Å; Y324-A327 PolarHBondContact O-N 2.74Å; Y324-V328 HydrophobicContact CD2-CG2 3.84Å; Y324-V328 HydrophobicContact CE2-CG2 3.36Å; Y324-V328 WeakPolarHBondContact O-CG2 3.37Å; Y324-V328 PolarHBondContact O-N 3.04Å
325	R	89	Confident	85.9	Confident	2 Å²	2	30.7 Å²	30.7	1%	0.008	17%	0.171	C	C	.	.	H	α-helix	trans	-64.3	-39	178.3	-68.3	-63.7	-60.8	-129.9	-4.1	112.7	Y69 I79 H137 D231 Y321 G322 Y323 V328 C329	Y69-R325 HydrophobicContact CE2-CB 4.45Å; Y69-R325 HydrophobicContact CE2-CG 4.35Å; Y69-R325 WeakPolarHBondContact OH-CG 3.25Å; I79-R325 HydrophobicContact CD1-CB 3.93Å; H137-R325 PolarHBondContact NE2-NH2 3.12Å; D231-R325 IonicContact OD1-CZ 3.69Å; D231-R325 IonicContact OD1-NH1 3.88Å; D231-R325 PolarHBondContact OD1-NH1 2.92Å; D231-R325 IonicContact OD1-NH2 2.99Å; Y321-R325 HydrophobicContact CD1-CG 4.02Å; Y321-R325 HydrophobicContact CE1-CG 3.62Å; Y321-R325 HydrophobicContact CE2-CG 4.39Å; Y321-R325 WeakPolarHBondContact O-CG 3.43Å; Y321-R325 PolarHBondContact O-N 2.58Å; Y321-R325 PolarHBondContact OH-NH1 3.25Å; G322-R325 PolarHBondContact O-N 3.41Å; Y323-R325 VanDerWaalsContact C-N 3.31Å; Y323-R325 PolarHBondContact O-N 2.82Å; R325-V328 PolarHBondContact O-N 3.27Å; R325-C329 PolarHBondContact O-N 3.38Å; R325-C329 PolarHBondContact O-SG 3.38Å
326	L	91.1	Very high	86.7	Confident	56 Å²	56	27.4 Å²	27.4	29%	0.293	15%	0.147	S	C	.	.	H	α-helix	trans	-63.2	-42.3	172.4	-68.9	175.1	0	0	0	111.9	I74 I78 G322 Y323 Y324 V328 C329 L330	I74-L326 HydrophobicContact CG2-CD2 3.94Å; I74-L326 HydrophobicContact CG2-CG 4.15Å; I78-L326 HydrophobicContact CB-CD2 4.43Å; I78-L326 HydrophobicContact CG2-CD2 3.64Å; G322-L326 WeakPolarHBondContact O-CG 2.97Å; G322-L326 PolarHBondContact O-N 3.27Å; Y323-L326 PolarHBondContact O-N 2.88Å; Y324-L326 PolarHBondContact O-N 3.38Å; L326-V328 VanDerWaalsContact C-N 3.32Å; L326-V328 PolarHBondContact O-N 3.41Å; L326-C329 VanDerWaalsContact O-CB 3.31Å; L326-C329 WeakPolarHBondContact O-CB 3.29Å; L326-C329 PolarHBondContact O-N 3.42Å; L326-C329 VanDerWaalsContact O-N 3.13Å; L326-L330 PolarHBondContact O-N 2.89Å
327	A	92.9	Very high	87.7	Confident	6 Å²	6	28.9 Å²	28.9	5%	0.05	15%	0.148	C	C	.	.	H	α-helix	trans	-66.8	-33.8	177.2	0	0	0	0	0	112.7	P300 L304 Y323 Y324 C329 L330 C331	P300-A327 HydrophobicContact CB-CB 4.14Å; L304-A327 HydrophobicContact CD1-CB 3.51Å; Y323-A327 WeakPolarHBondContact O-CB 3.16Å; Y323-A327 PolarHBondContact O-N 3.22Å; Y324-A327 PolarHBondContact O-N 2.74Å; A327-C329 VanDerWaalsContact C-N 3.34Å; A327-L330 WeakPolarHBondContact O-CB 3.41Å; A327-L330 PolarHBondContact O-N 3.02Å; A327-C331 PolarHBondContact O-N 2.03Å
328	V	91.8	Very high	88.3	Confident	2 Å²	2	27.1 Å²	27.1	1%	0.012	14%	0.139	C	C	.	.	H	α-helix	trans	-64.3	-38.4	170.6	166.1	0	0	0	0	111.3	F157 S301 Y324 R325 L326 L330 C331 C332	F157-V328 HydrophobicContact CE1-CG1 3.56Å; F157-V328 HydrophobicContact CZ-CG1 3.34Å; S301-V328 WeakPolarHBondContact OG-CG2 3.33Å; Y324-V328 HydrophobicContact CD2-CG2 3.84Å; Y324-V328 HydrophobicContact CE2-CG2 3.36Å; Y324-V328 WeakPolarHBondContact O-CG2 3.37Å; Y324-V328 PolarHBondContact O-N 3.04Å; R325-V328 PolarHBondContact O-N 3.27Å; L326-V328 VanDerWaalsContact C-N 3.32Å; L326-V328 PolarHBondContact O-N 3.41Å; V328-L330 VanDerWaalsContact C-N 3.34Å; V328-C331 WeakPolarHBondContact O-CA 3.18Å; V328-C331 VanDerWaalsContact O-CB 3.24Å; V328-C331 WeakPolarHBondContact O-CB 3.48Å; V328-C331 PolarHBondContact O-N 3.47Å; V328-C331 VanDerWaalsContact O-N 3.15Å; V328-C332 PolarHBondContact O-N 2.84Å; V328-C332 PolarHBondContact O-SG 2.86Å
329	C	93.3	Very high	88.7	Confident	6 Å²	6	27.1 Å²	27.1	4%	0.041	14%	0.14	C	C	.	.	H	α-helix	trans	-61.7	-44	173.1	-62.2	0	0	0	0	111.4	S82 Y83 R325 L326 A327 C331 C332 F333	S82-C329 VanDerWaalsContact OG-CB 3.29Å; S82-C329 WeakPolarHBondContact OG-CB 3.04Å; S82-C329 PolarHBondContact OG-SG 2.76Å; S82-C329 VanDerWaalsContact OG-SG 3.35Å; Y83-C329 HydrophobicContact CE1-CB 4.4Å; R325-C329 PolarHBondContact O-N 3.38Å; R325-C329 PolarHBondContact O-SG 3.38Å; L326-C329 VanDerWaalsContact O-CB 3.31Å; L326-C329 WeakPolarHBondContact O-CB 3.29Å; L326-C329 PolarHBondContact O-N 3.42Å; L326-C329 VanDerWaalsContact O-N 3.13Å; A327-C329 VanDerWaalsContact C-N 3.34Å; C329-C331 VanDerWaalsContact C-N 3.25Å; C329-C331 PolarHBondContact O-N 3.46Å; C329-C332 WeakPolarHBondContact O-CB 3.14Å; C329-C332 PolarHBondContact O-N 3.24Å; C329-C332 VanDerWaalsContact O-N 3.17Å; C329-F333 VanDerWaalsContact O-CD2 3.26Å; C329-F333 WeakPolarHBondContact O-CD2 3.27Å
330	L	93.7	Very high	88.8	Confident	68 Å²	68	29.2 Å²	29.2	36%	0.356	14%	0.142	S	C	.	.	H	α-helix	trans	-59	-39	172.8	-175.7	59.3	0	0	0	111.9	V296 P300 L326 A327 V328 C332 F333	V296-L330 HydrophobicContact CG1-CD1 4.42Å; V296-L330 HydrophobicContact CG1-CD2 4.42Å; V296-L330 WeakPolarHBondContact O-CD2 3.41Å; V296-L330 WeakPolarHBondContact O-CG 3.02Å; P300-L330 HydrophobicContact CG-CD2 4.39Å; L326-L330 PolarHBondContact O-N 2.89Å; A327-L330 WeakPolarHBondContact O-CB 3.41Å; A327-L330 PolarHBondContact O-N 3.02Å; V328-L330 VanDerWaalsContact C-N 3.34Å; L330-C332 VanDerWaalsContact C-N 3.35Å; L330-C332 PolarHBondContact O-N 3Å; L330-F333 PolarHBondContact O-N 2.89Å
331	C	93.4	Very high	88.8	Confident	0 Å²	0	27.8 Å²	27.8	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-60.9	-41.4	176	-169	0	0	0	0	111.9	C297 F298 A327 V328 C329 F333 H334	C297-C331 WeakPolarHBondContact O-CA 3.47Å; C297-C331 VanDerWaalsContact O-CB 3.25Å; C297-C331 WeakPolarHBondContact O-CB 3.39Å; C297-C331 PolarHBondContact O-N 3.03Å; F298-C331 VanDerWaalsContact CD1-SG 3.52Å; A327-C331 PolarHBondContact O-N 2.03Å; V328-C331 WeakPolarHBondContact O-CA 3.18Å; V328-C331 VanDerWaalsContact O-CB 3.24Å; V328-C331 WeakPolarHBondContact O-CB 3.48Å; V328-C331 PolarHBondContact O-N 3.47Å; V328-C331 VanDerWaalsContact O-N 3.15Å; C329-C331 VanDerWaalsContact C-N 3.25Å; C329-C331 PolarHBondContact O-N 3.46Å; C331-F333 PolarHBondContact O-N 3.36Å; C331-H334 PolarHBondContact O-N 3.3Å; C331-H334 VanDerWaalsContact O-N 3.12Å; C331-H334 PolarHBondContact O-ND1 3.44Å
332	C	93.2	Very high	88.7	Confident	0 Å²	0	28 Å²	28	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-60	-27.9	-178.8	-65.9	0	0	0	0	113.6	T86 V328 C329 L330 H334 S335	T86-C332 HydrophobicContact CG2-CB 4.12Å; T86-C332 WeakPolarHBondContact CG2-O 3.17Å; V328-C332 PolarHBondContact O-N 2.84Å; V328-C332 PolarHBondContact O-SG 2.86Å; C329-C332 WeakPolarHBondContact O-CB 3.14Å; C329-C332 PolarHBondContact O-N 3.24Å; C329-C332 VanDerWaalsContact O-N 3.17Å; L330-C332 VanDerWaalsContact C-N 3.35Å; L330-C332 PolarHBondContact O-N 3Å; C332-H334 PolarHBondContact O-N 3.2Å; C332-H334 VanDerWaalsContact O-N 3.14Å; C332-S335 PolarHBondContact O-N 3.37Å; C332-S335 PolarHBondContact O-OG 3.32Å
333	F	92.5	Very high	88.6	Confident	53 Å²	53	32 Å²	32	23%	0.232	15%	0.153	C	C	.	.	T	Hydrogen-bonded Turn	trans	-66.2	-10.5	177.1	-71.5	-70.1	0	0	0	114.5	L85 C329 L330 C331 S335 C336	L85-F333 HydrophobicContact CB-CE1 4.06Å; L85-F333 HydrophobicContact CB-CZ 4.35Å; L85-F333 HydrophobicContact CD2-CE1 3.61Å; L85-F333 HydrophobicContact CD2-CZ 3.87Å; L85-F333 HydrophobicContact CG-CE1 3.78Å; L85-F333 HydrophobicContact CG-CZ 4.35Å; C329-F333 VanDerWaalsContact O-CD2 3.26Å; C329-F333 WeakPolarHBondContact O-CD2 3.27Å; L330-F333 PolarHBondContact O-N 2.89Å; C331-F333 PolarHBondContact O-N 3.36Å; F333-S335 PolarHBondContact O-N 3.41Å; F333-C336 VanDerWaalsContact O-CB 3.27Å; F333-C336 WeakPolarHBondContact O-CB 3.44Å; F333-C336 PolarHBondContact O-N 3.07Å
334	H	91.8	Very high	88.2	Confident	0 Å²	0	26.8 Å²	26.8	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-55.7	-38.2	173.1	76.9	-89.1	0	0	0	112	D123 S164 I293 C297 F298 C331 C332 C336 L337 D338	D123-H334 IonicContact OD1-NE2 3.01Å; S164-H334 WeakPolarHBondContact CB-NE2 3.48Å; S164-H334 PolarHBondContact OG-CE1 3.36Å; S164-H334 PolarHBondContact OG-NE2 3.39Å; I293-H334 HydrophobicContact CG2-CB 4.16Å; C297-H334 HydrophobicContact CB-CB 4.22Å; F298-H334 HydrophobicContact CE2-CB 3.44Å; F298-H334 VanDerWaalsContact CE2-CB 3.44Å; F298-H334 AromaticContact CE2-CG 3.75Å; F298-H334 HydrophobicContact CZ-CB 3.61Å; F298-H334 AromaticContact CZ-CD2 3.75Å; F298-H334 AromaticContact CZ-CG 3.34Å; F298-H334 AromaticContact CZ-ND1 3.57Å; C331-H334 PolarHBondContact O-N 3.3Å; C331-H334 VanDerWaalsContact O-N 3.12Å; C331-H334 PolarHBondContact O-ND1 3.44Å; C332-H334 PolarHBondContact O-N 3.2Å; C332-H334 VanDerWaalsContact O-N 3.14Å; H334-C336 PolarHBondContact O-N 3.27Å; H334-C336 VanDerWaalsContact O-N 3.11Å; H334-L337 WeakPolarHBondContact O-CA 3.11Å; H334-L337 WeakPolarHBondContact O-CB 3.47Å; H334-L337 PolarHBondContact O-N 2.85Å; H334-D338 IonicContact CD2-OD2 3.9Å; H334-D338 PolarHBondContact O-N 3.43Å
335	S	90.1	Very high	87.7	Confident	0 Å²	0	27.9 Å²	27.9	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-59.8	-23.7	178.4	62.1	0	0	0	0	113.2	T86 D123 C332 F333 L337 D338	T86-S335 WeakPolarHBondContact CG2-OG 3.31Å; D123-S335 WeakPolarHBondContact OD2-CA 3.4Å; D123-S335 WeakPolarHBondContact OD2-CB 3.46Å; C332-S335 PolarHBondContact O-N 3.37Å; C332-S335 PolarHBondContact O-OG 3.32Å; F333-S335 PolarHBondContact O-N 3.41Å; S335-L337 VanDerWaalsContact C-N 3.34Å; S335-D338 WeakPolarHBondContact CA-OD2 3.33Å
336	C	88.6	Confident	87.1	Confident	13 Å²	13	28.5 Å²	28.5	9%	0.088	15%	0.145	C	C	.	.	H	α-helix	trans	-79.3	-20.4	175.7	-56.9	0	0	0	0	112.3	V89 F333 H334	V89-C336 HydrophobicContact CB-CB 4.27Å; V89-C336 HydrophobicContact CG1-CB 3.63Å; F333-C336 VanDerWaalsContact O-CB 3.27Å; F333-C336 WeakPolarHBondContact O-CB 3.44Å; F333-C336 PolarHBondContact O-N 3.07Å; H334-C336 PolarHBondContact O-N 3.27Å; H334-C336 VanDerWaalsContact O-N 3.11Å
337	L	88.3	Confident	86.4	Confident	58 Å²	58	29.8 Å²	29.8	30%	0.304	15%	0.152	S	C	.	.	H	α-helix	trans	-93.9	-13.4	-177.5	-57.9	175.6	0	0	0	112.2	I293 H334 S335 F340 L341	I293-L337 HydrophobicContact CD1-CB 3.89Å; I293-L337 HydrophobicContact CD1-CD1 4.38Å; I293-L337 HydrophobicContact CG1-CB 4.2Å; I293-L337 HydrophobicContact CG1-CD1 3.75Å; H334-L337 WeakPolarHBondContact O-CA 3.11Å; H334-L337 WeakPolarHBondContact O-CB 3.47Å; H334-L337 PolarHBondContact O-N 2.85Å; S335-L337 VanDerWaalsContact C-N 3.34Å; L337-F340 WeakPolarHBondContact O-CB 3.4Å; L337-F340 PolarHBondContact O-N 3.26Å; L337-F340 VanDerWaalsContact O-N 3.16Å; L337-L341 PolarHBondContact O-N 3.47Å; L337-L341 VanDerWaalsContact O-N 3.08Å
338	D	85.7	Confident	85.2	Confident	1 Å²	1	29.6 Å²	29.6	1%	0.005	15%	0.151	C	C	.	.	H	α-helix	trans	-61.8	-35.1	-178.4	-74.4	-36	0	0	0	115	I97 L119 D123 H334 S335 F340 L341 C342	I97-D338 HydrophobicContact CD1-CB 4.44Å; L119-D338 HydrophobicContact CD2-CB 3.82Å; L119-D338 HydrophobicContact CG-CB 4.26Å; D123-D338 VanDerWaalsContact OD2-OD2 3.06Å; H334-D338 IonicContact CD2-OD2 3.9Å; H334-D338 PolarHBondContact O-N 3.43Å; S335-D338 WeakPolarHBondContact CA-OD2 3.33Å; D338-F340 PolarHBondContact O-N 2.97Å; D338-L341 WeakPolarHBondContact O-CB 3.31Å; D338-L341 PolarHBondContact O-N 2.94Å; D338-C342 WeakPolarHBondContact O-CB 3.38Å; D338-C342 PolarHBondContact O-N 3.38Å; D338-C342 PolarHBondContact O-SG 2.83Å; D338-C342 VanDerWaalsContact O-SG 3.39Å
339	P	82	Confident	83.8	Confident	16 Å²	16	31.1 Å²	31.1	10%	0.104	17%	0.167	C	C	.	.	H	α-helix	trans	-63.2	-38.6	172.1	-23	32.6	0	0	0	113.5	S93 I97 L341 C342 M343	S93-P339 WeakPolarHBondContact OG-CG 3.47Å; I97-P339 HydrophobicContact CD1-CG 4.28Å; P339-L341 VanDerWaalsContact C-N 3.32Å; P339-C342 PolarHBondContact O-N 3.2Å; P339-M343 VanDerWaalsContact O-CB 3.26Å; P339-M343 WeakPolarHBondContact O-CB 3.25Å; P339-M343 PolarHBondContact O-N 2.88Å
340	F	81.9	Confident	81.8	Confident	128 Å²	128	35.6 Å²	35.6	56%	0.561	19%	0.19	S	C	*	.	H	α-helix	trans	-65.3	-42.7	176.5	-64.2	-84.9	0	0	0	110.1	L289 L337 D338 M343 L344	L289-F340 HydrophobicContact CD2-CB 4.44Å; L337-F340 WeakPolarHBondContact O-CB 3.4Å; L337-F340 PolarHBondContact O-N 3.26Å; L337-F340 VanDerWaalsContact O-N 3.16Å; D338-F340 PolarHBondContact O-N 2.97Å; F340-M343 PolarHBondContact O-N 2.78Å; F340-L344 WeakPolarHBondContact O-CB 3.35Å; F340-L344 VanDerWaalsContact O-CG 3.32Å; F340-L344 WeakPolarHBondContact O-CG 3.44Å; F340-L344 PolarHBondContact O-N 3.44Å
341	L	83.6	Confident	79.7	Confident	1 Å²	1	33.5 Å²	33.5	1%	0.005	18%	0.181	C	C	.	.	H	α-helix	trans	-60.7	-49.1	174.3	-179.9	58.5	0	0	0	111.3	I171 V286 V290 L337 D338 P339 M343 L344 L345	I171-L341 HydrophobicContact CD1-CD2 3.99Å; V286-L341 HydrophobicContact CG1-CD1 4.39Å; V290-L341 HydrophobicContact CG2-CD1 3.32Å; V290-L341 HydrophobicContact CG2-CD2 4.44Å; L337-L341 PolarHBondContact O-N 3.47Å; L337-L341 VanDerWaalsContact O-N 3.08Å; D338-L341 WeakPolarHBondContact O-CB 3.31Å; D338-L341 PolarHBondContact O-N 2.94Å; P339-L341 VanDerWaalsContact C-N 3.32Å; L341-M343 PolarHBondContact O-N 3.23Å; L341-L344 PolarHBondContact O-N 3.09Å; L341-L345 HydrophobicContact CD1-CD1 3.8Å; L341-L345 HydrophobicContact CD1-CG 4.09Å; L341-L345 HydrophobicContact CG-CD1 3.71Å; L341-L345 HydrophobicContact CG-CG 4.45Å; L341-L345 WeakPolarHBondContact O-CB 3.46Å; L341-L345 WeakPolarHBondContact O-CD1 3.04Å; L341-L345 VanDerWaalsContact O-CG 3.24Å; L341-L345 WeakPolarHBondContact O-CG 3.22Å; L341-L345 PolarHBondContact O-N 2.99Å
342	C	80.1	Confident	77.7	Confident	8 Å²	8	34.9 Å²	34.9	5%	0.054	19%	0.187	C	C	.	.	H	α-helix	trans	-61.8	-41.5	177.9	-78.6	0	0	0	0	112.7	I97 Y116 D338 P339 S346	I97-C342 HydrophobicContact CD1-CB 4.42Å; I97-C342 HydrophobicContact CG1-CB 4.35Å; Y116-C342 HydrophobicContact CE1-CB 4.31Å; Y116-C342 HydrophobicContact CE2-CB 4.17Å; Y116-C342 PolarHBondContact OH-O 3.09Å; D338-C342 WeakPolarHBondContact O-CB 3.38Å; D338-C342 PolarHBondContact O-N 3.38Å; D338-C342 PolarHBondContact O-SG 2.83Å; D338-C342 VanDerWaalsContact O-SG 3.39Å; P339-C342 PolarHBondContact O-N 3.2Å; C342-S346 VanDerWaalsContact O-CB 3.31Å; C342-S346 WeakPolarHBondContact O-CB 3.47Å; C342-S346 PolarHBondContact O-N 3.05Å
343	M	80.3	Confident	75.7	Confident	96 Å²	96	40.6 Å²	40.6	47%	0.473	22%	0.217	S	C	.	.	H	α-helix	trans	-61.9	-55.8	176.5	-174.6	-172.2	-65.4	0	0	109.6	P339 F340 L341 L345 S346 L347	P339-M343 VanDerWaalsContact O-CB 3.26Å; P339-M343 WeakPolarHBondContact O-CB 3.25Å; P339-M343 PolarHBondContact O-N 2.88Å; F340-M343 PolarHBondContact O-N 2.78Å; L341-M343 PolarHBondContact O-N 3.23Å; M343-L345 PolarHBondContact O-N 3.12Å; M343-S346 WeakPolarHBondContact O-CB 3Å; M343-S346 PolarHBondContact O-N 3.06Å; M343-S346 PolarHBondContact O-OG 3.14Å; M343-L347 HydrophobicContact CG-CD1 4.06Å; M343-L347 WeakPolarHBondContact O-CD1 3.45Å; M343-L347 PolarHBondContact O-N 3.28Å; M343-L347 VanDerWaalsContact O-N 3.16Å
344	L	80.5	Confident	73.6	Confident	44 Å²	44	44.4 Å²	44.4	23%	0.23	24%	0.235	C	C	.	.	H	α-helix	trans	-62	-40.8	-179.1	-70	174	0	0	0	112.8	L282 V286 L289 F340 L341 S346 L347 T348	L282-L344 HydrophobicContact CD1-CD2 3.96Å; V286-L344 HydrophobicContact CG2-CB 3.67Å; L289-L344 HydrophobicContact CD2-CD1 3.53Å; F340-L344 WeakPolarHBondContact O-CB 3.35Å; F340-L344 VanDerWaalsContact O-CG 3.32Å; F340-L344 WeakPolarHBondContact O-CG 3.44Å; F340-L344 PolarHBondContact O-N 3.44Å; L341-L344 PolarHBondContact O-N 3.09Å; L344-S346 VanDerWaalsContact C-N 3.28Å; L344-S346 PolarHBondContact O-N 2.76Å; L344-L347 PolarHBondContact O-N 3.46Å; L344-T348 WeakPolarHBondContact O-CG2 3.13Å; L344-T348 PolarHBondContact O-N 2.87Å; L344-T348 VanDerWaalsContact O-N 3.09Å
345	L	79	Confident	71.6	Confident	28 Å²	28	45.9 Å²	45.9	15%	0.147	24%	0.242	C	C	.	.	H	α-helix	trans	-59.4	-40.5	173.2	-81.4	165.6	0	0	0	111.4	Y116 I171 V286 L341 M343 L347 T348 G349	Y116-L345 HydrophobicContact CE1-CB 4.5Å; Y116-L345 HydrophobicContact CE1-CD1 4.2Å; Y116-L345 WeakPolarHBondContact OH-CB 3.21Å; I171-L345 HydrophobicContact CG2-CD1 4.28Å; I171-L345 HydrophobicContact CG2-CD2 4.32Å; V286-L345 HydrophobicContact CG1-CD2 4.11Å; V286-L345 HydrophobicContact CG1-CG 4.29Å; L341-L345 HydrophobicContact CD1-CD1 3.8Å; L341-L345 HydrophobicContact CD1-CG 4.09Å; L341-L345 HydrophobicContact CG-CD1 3.71Å; L341-L345 HydrophobicContact CG-CG 4.45Å; L341-L345 WeakPolarHBondContact O-CB 3.46Å; L341-L345 WeakPolarHBondContact O-CD1 3.04Å; L341-L345 VanDerWaalsContact O-CG 3.24Å; L341-L345 WeakPolarHBondContact O-CG 3.22Å; L341-L345 PolarHBondContact O-N 2.99Å; M343-L345 PolarHBondContact O-N 3.12Å; L345-L347 VanDerWaalsContact C-N 3.32Å; L345-L347 PolarHBondContact O-N 3.25Å; L345-T348 PolarHBondContact O-N 2.91Å; L345-T348 PolarHBondContact O-OG1 3.27Å; L345-G349 PolarHBondContact O-N 3Å; L345-G349 VanDerWaalsContact O-N 3.12Å
346	S	75.8	Confident	70	Confident	14 Å²	14	49.1 Å²	49.1	10%	0.098	26%	0.258	C	S	.	.	H	α-helix	trans	-64.6	-36.6	179.7	80.9	0	0	0	0	112.4	Y116 C342 M343 L344 G349	Y116-S346 PolarHBondContact OH-N 2.7Å; C342-S346 VanDerWaalsContact O-CB 3.31Å; C342-S346 WeakPolarHBondContact O-CB 3.47Å; C342-S346 PolarHBondContact O-N 3.05Å; M343-S346 WeakPolarHBondContact O-CB 3Å; M343-S346 PolarHBondContact O-N 3.06Å; M343-S346 PolarHBondContact O-OG 3.14Å; L344-S346 VanDerWaalsContact C-N 3.28Å; L344-S346 PolarHBondContact O-N 2.76Å; S346-G349 PolarHBondContact O-N 3.43Å
347	L	75.8	Confident	68.2	Low	83 Å²	83	51.3 Å²	51.3	44%	0.435	27%	0.274	S	S	.	.	H	α-helix	trans	-68	-39	173.7	-79.7	80.7	0	0	0	111.2	L282 M343 L344 L345 G349 D350 S351	L282-L347 HydrophobicContact CD2-CB 3.69Å; M343-L347 HydrophobicContact CG-CD1 4.06Å; M343-L347 WeakPolarHBondContact O-CD1 3.45Å; M343-L347 PolarHBondContact O-N 3.28Å; M343-L347 VanDerWaalsContact O-N 3.16Å; L344-L347 PolarHBondContact O-N 3.46Å; L345-L347 VanDerWaalsContact C-N 3.32Å; L345-L347 PolarHBondContact O-N 3.25Å; L347-G349 VanDerWaalsContact C-N 3.27Å; L347-G349 PolarHBondContact O-N 3.05Å; L347-D350 PolarHBondContact O-N 3.43Å; L347-S351 PolarHBondContact O-N 3.5Å; L347-S351 PolarHBondContact O-OG 3.23Å; L347-S351 VanDerWaalsContact O-OG 3.09Å
348	T	68.3	Low	66.5	Low	3 Å²	3	50.1 Å²	50.1	2%	0.018	27%	0.27	C	S	.	.	H	α-helix	trans	-69.1	-23.6	178.8	64.7	0	0	0	0	114	R175 L282 F283 V286 L344 L345 D350 S351 E352	R175-T348 PolarHBondContact NH1-OG1 3.28Å; L282-T348 HydrophobicContact CD2-CG2 3.72Å; L282-T348 HydrophobicContact CG-CG2 3.68Å; F283-T348 HydrophobicContact CD2-CG2 4.24Å; F283-T348 HydrophobicContact CE2-CG2 4.26Å; V286-T348 HydrophobicContact CG2-CG2 3.64Å; L344-T348 WeakPolarHBondContact O-CG2 3.13Å; L344-T348 PolarHBondContact O-N 2.87Å; L344-T348 VanDerWaalsContact O-N 3.09Å; L345-T348 PolarHBondContact O-N 2.91Å; L345-T348 PolarHBondContact O-OG1 3.27Å; T348-D350 VanDerWaalsContact C-N 3.29Å; T348-D350 PolarHBondContact O-N 3.19Å; T348-S351 CarbonylContact O-C 3.58Å; T348-S351 PolarHBondContact O-N 2.47Å; T348-E352 PolarHBondContact O-N 3.01Å
349	G	61.4	Low	65.1	Low	34 Å²	34	52.9 Å²	52.9	35%	0.351	29%	0.285	S	S	.	.	H	α-helix	trans	-62.7	-38	175	0	0	0	0	0	112.1	L345 S346 L347	L345-G349 PolarHBondContact O-N 3Å; L345-G349 VanDerWaalsContact O-N 3.12Å; S346-G349 PolarHBondContact O-N 3.43Å; L347-G349 VanDerWaalsContact C-N 3.27Å; L347-G349 PolarHBondContact O-N 3.05Å
350	D	52.1	Low	63.8	Low	100 Å²	100	59.8 Å²	59.8	54%	0.535	31%	0.309	S	S	.	.	H	α-helix	trans	-74.9	-32.3	176.7	-58.7	-25.8	0	0	0	110.6	L347 T348	L347-D350 PolarHBondContact O-N 3.43Å; T348-D350 VanDerWaalsContact C-N 3.29Å; T348-D350 PolarHBondContact O-N 3.19Å
351	S	50.3	Low	62.4	Low	23 Å²	23	59.3 Å²	59.3	16%	0.161	31%	0.311	C	S	.	.	H	α-helix	trans	-74.9	-22.2	174.1	-46.3	0	0	0	0	114.7	L347 T348 I353 Q354 F355	L347-S351 PolarHBondContact O-N 3.5Å; L347-S351 PolarHBondContact O-OG 3.23Å; L347-S351 VanDerWaalsContact O-OG 3.09Å; T348-S351 CarbonylContact O-C 3.58Å; T348-S351 PolarHBondContact O-N 2.47Å; S351-I353 PolarHBondContact O-N 3.4Å; S351-Q354 CarbonylContact O-C 3.57Å; S351-Q354 WeakPolarHBondContact O-CA 3.37Å; S351-Q354 WeakPolarHBondContact O-CB 3.46Å; S351-Q354 PolarHBondContact O-N 2.82Å; S351-F355 PolarHBondContact O-N 3.2Å
352	E	51.4	Low	61.1	Low	29 Å²	29	64.6 Å²	64.6	14%	0.136	34%	0.339	C	S	.	.	H	α-helix	trans	-60.8	-31.4	173.7	-117.3	-168.7	-151.8	0	0	111.2	Y185 K190 F283 T348 F355 I356	Y185-E352 WeakPolarHBondContact CE1-OE1 3.34Å; Y185-E352 PolarHBondContact OH-OE1 3.33Å; K190-E352 IonicContact NZ-OE2 2.94Å; K190-E352 PolarHBondContact NZ-OE2 2.64Å; F283-E352 HydrophobicContact CZ-CG 4.36Å; T348-E352 PolarHBondContact O-N 3.01Å; E352-F355 PolarHBondContact O-N 3.43Å; E352-I356 WeakPolarHBondContact O-CG1 3.26Å; E352-I356 PolarHBondContact O-N 2.84Å
353	I	51.2	Low	59.8	Low	121 Å²	121	72 Å²	72	62%	0.621	37%	0.365	S	S	*	.	H	α-helix	trans	-69	-39.1	174.1	-61.1	171.3	0	0	0	110.1	S351 I356 S357	S351-I353 PolarHBondContact O-N 3.4Å; I353-I356 PolarHBondContact O-N 3.24Å; I353-S357 PolarHBondContact O-N 3.43Å
354	Q	47.2	Very low	58	Low	132 Å²	132	77.2 Å²	77.2	62%	0.617	38%	0.38	S	S	*	.	H	α-helix	trans	-69.6	-32.2	173.6	-66.5	-180	-23.8	0	0	112.3	S351 S357 C358	S351-Q354 CarbonylContact O-C 3.57Å; S351-Q354 WeakPolarHBondContact O-CA 3.37Å; S351-Q354 WeakPolarHBondContact O-CB 3.46Å; S351-Q354 PolarHBondContact O-N 2.82Å; Q354-S357 CarbonylContact O-C 3.58Å; Q354-S357 WeakPolarHBondContact O-CA 3.46Å; Q354-S357 VanDerWaalsContact O-CB 3.28Å; Q354-S357 WeakPolarHBondContact O-CB 3.07Å; Q354-S357 PolarHBondContact O-N 2.86Å; Q354-C358 PolarHBondContact O-N 3.26Å
355	F	50.9	Low	56.2	Low	32 Å²	32	80 Å²	80	14%	0.14	40%	0.401	C	S	.	.	H	α-helix	trans	-61.1	-43.7	172.5	-179.6	-84	0	0	0	112.4	P182 W280 S351 E352 S357 C358 N359	P182-F355 HydrophobicContact CB-CE1 3.86Å; P182-F355 HydrophobicContact CB-CZ 4.28Å; W280-F355 HydrophobicContact CE3-CD2 4.23Å; W280-F355 HydrophobicContact CH2-CB 3.72Å; W280-F355 AromaticContact CH2-CD2 3.2Å; W280-F355 HydrophobicContact CH2-CD2 3.2Å; W280-F355 HydrophobicContact CH2-CE2 4.12Å; W280-F355 AromaticContact CH2-CG 3.84Å; W280-F355 HydrophobicContact CH2-CG 3.84Å; W280-F355 AromaticContact CZ2-CD2 3.49Å; W280-F355 HydrophobicContact CZ2-CD2 3.49Å; W280-F355 VanDerWaalsContact CZ2-CD2 3.49Å; W280-F355 AromaticContact CZ2-CE2 3.95Å; W280-F355 HydrophobicContact CZ2-CE2 3.95Å; W280-F355 HydrophobicContact CZ2-CG 4.44Å; W280-F355 HydrophobicContact CZ3-CB 3.87Å; W280-F355 AromaticContact CZ3-CD2 3.55Å; W280-F355 HydrophobicContact CZ3-CD2 3.55Å; W280-F355 HydrophobicContact CZ3-CG 4.19Å; S351-F355 PolarHBondContact O-N 3.2Å; E352-F355 PolarHBondContact O-N 3.43Å; F355-S357 PolarHBondContact O-N 3.1Å; F355-C358 PolarHBondContact O-N 3.37Å; F355-N359 WeakPolarHBondContact O-CB 3.46Å; F355-N359 PolarHBondContact O-N 3.26Å; F355-N359 VanDerWaalsContact O-N 3.13Å
356	I	54.8	Low	54.8	Low	67 Å²	67	82.6 Å²	82.6	34%	0.344	43%	0.426	S	S	.	.	H	α-helix	trans	-61.6	-32.3	172.6	-64.4	168.3	0	0	0	110.7	E352 I353 R360	E352-I356 WeakPolarHBondContact O-CG1 3.26Å; E352-I356 PolarHBondContact O-N 2.84Å; I353-I356 PolarHBondContact O-N 3.24Å; I356-R360 VanDerWaalsContact O-CB 3.28Å; I356-R360 WeakPolarHBondContact O-CB 3.22Å; I356-R360 PolarHBondContact O-N 2.81Å
357	S	52.5	Low	53.4	Low	60 Å²	60	88.2 Å²	88.2	42%	0.42	46%	0.46	S	S	.	.	H	α-helix	trans	-74.2	-50.3	176.9	-161.3	0	0	0	0	113.1	I353 Q354 F355 N359 R360 I361	I353-S357 PolarHBondContact O-N 3.43Å; Q354-S357 CarbonylContact O-C 3.58Å; Q354-S357 WeakPolarHBondContact O-CA 3.46Å; Q354-S357 VanDerWaalsContact O-CB 3.28Å; Q354-S357 WeakPolarHBondContact O-CB 3.07Å; Q354-S357 PolarHBondContact O-N 2.86Å; F355-S357 PolarHBondContact O-N 3.1Å; S357-N359 VanDerWaalsContact C-N 3.3Å; S357-N359 PolarHBondContact O-N 3.13Å; S357-R360 CarbonylContact O-C 3.04Å; S357-R360 WeakPolarHBondContact O-CA 3.43Å; S357-R360 WeakPolarHBondContact O-CB 3.32Å; S357-R360 PolarHBondContact O-N 3.21Å; S357-I361 WeakPolarHBondContact O-CG1 3.14Å; S357-I361 PolarHBondContact O-N 3.37Å
358	C	52.2	Low	51.9	Low	33 Å²	33	91.5 Å²	91.5	22%	0.223	48%	0.476	C	S	.	.	H	α-helix	trans	-58.8	-42.1	179.5	-152.3	0	0	0	0	110.8	C278 W280 Q354 F355 R360 I361 L362	C278-C358 HydrophobicContact CB-CB 4.38Å; C278-C358 WeakPolarHBondContact CB-SG 3.24Å; C278-C358 WeakPolarHBondContact SG-CB 3.05Å; C278-C358 CovalentContact SG-SG 2.08Å; C278-C358 PolarHBondContact SG-SG 2.95Å; W280-C358 HydrophobicContact CH2-CB 4.47Å; Q354-C358 PolarHBondContact O-N 3.26Å; F355-C358 PolarHBondContact O-N 3.37Å; C358-R360 VanDerWaalsContact C-N 3.31Å; C358-R360 PolarHBondContact O-N 3.37Å; C358-I361 PolarHBondContact O-N 3.29Å; C358-L362 PolarHBondContact O-N 3.3Å
359	N	55.8	Low	50.6	Low	58 Å²	58	99 Å²	99	31%	0.31	54%	0.538	S	S	.	.	H	α-helix	trans	-71.9	-24.8	178.5	-147.2	-6	0	0	0	112.8	F355 S357 R363	F355-N359 WeakPolarHBondContact O-CB 3.46Å; F355-N359 PolarHBondContact O-N 3.26Å; F355-N359 VanDerWaalsContact O-N 3.13Å; S357-N359 VanDerWaalsContact C-N 3.3Å; S357-N359 PolarHBondContact O-N 3.13Å; N359-R363 WeakPolarHBondContact O-CB 3.32Å; N359-R363 WeakPolarHBondContact O-CG 3.34Å; N359-R363 PolarHBondContact O-N 3.47Å
360	R	54.3	Low	50.1	Low	161 Å²	161	102.3 Å²	102.3	61%	0.608	55%	0.548	S	S	*	.	H	α-helix	trans	-76.8	-32.4	171.4	-159	-173.4	-66.9	-173.4	-0.7	111.4	I356 S357 C358 R364	I356-R360 VanDerWaalsContact O-CB 3.28Å; I356-R360 WeakPolarHBondContact O-CB 3.22Å; I356-R360 PolarHBondContact O-N 2.81Å; S357-R360 CarbonylContact O-C 3.04Å; S357-R360 WeakPolarHBondContact O-CA 3.43Å; S357-R360 WeakPolarHBondContact O-CB 3.32Å; S357-R360 PolarHBondContact O-N 3.21Å; C358-R360 VanDerWaalsContact C-N 3.31Å; C358-R360 PolarHBondContact O-N 3.37Å; R360-R364 PolarHBondContact O-N 3.1Å
361	I	53.7	Low	50	Low	118 Å²	118	102.4 Å²	102.4	61%	0.605	55%	0.549	S	S	*	.	H	α-helix	trans	-70.4	-48.5	174.8	-67.4	164.4	0	0	0	110.5	S357 C358 R363 R364	S357-I361 WeakPolarHBondContact O-CG1 3.14Å; S357-I361 PolarHBondContact O-N 3.37Å; C358-I361 PolarHBondContact O-N 3.29Å; I361-R363 PolarHBondContact O-N 3.18Å; I361-R364 PolarHBondContact O-N 3.06Å
362	L	55	Low	50	Low	113 Å²	113	106.8 Å²	106.8	59%	0.592	57%	0.57	S	S	*	*	T	Hydrogen-bonded Turn	trans	-63.7	-18.7	175.5	-101.2	109.8	0	0	0	114	C358	C358-L362 PolarHBondContact O-N 3.3Å
363	R	53.7	Low	49.9	Very low	162 Å²	162	111.4 Å²	111.4	61%	0.611	60%	0.596	S	S	*	*	T	Hydrogen-bonded Turn	trans	-105.6	0.8	179.6	-76.9	-171	179.1	-147.6	-4.1	114.9	N359 I361 P365	N359-R363 WeakPolarHBondContact O-CB 3.32Å; N359-R363 WeakPolarHBondContact O-CG 3.34Å; N359-R363 PolarHBondContact O-N 3.47Å; I361-R363 PolarHBondContact O-N 3.18Å; R363-P365 WeakPolarHBondContact O-CD 3.47Å; R363-P365 VanDerWaalsContact O-N 3.16Å
364	R	43.3	Very low	49.8	Very low	206 Å²	206	110.8 Å²	110.8	78%	0.777	59%	0.594	S	S	*	*	S	Bend	trans	-67.1	113.8	162.4	-85.3	-170.8	179.3	-172.7	0.2	105.6	R360 I361 A366	R360-R364 PolarHBondContact O-N 3.1Å; I361-R364 PolarHBondContact O-N 3.06Å; R364-A366 PolarHBondContact O-N 2.9Å
365	P	41.9	Very low	50	Low	103 Å²	103	109.3 Å²	109.3	67%	0.669	59%	0.593	S	S	*	*			trans	-54	132.8	163.3	25.1	-31.3	0	0	0	105.8	R363 V367	R363-P365 WeakPolarHBondContact O-CD 3.47Å; R363-P365 VanDerWaalsContact O-N 3.16Å; P365-V367 HydrophobicContact CG-CG2 4.45Å; P365-V367 PolarHBondContact O-N 2.85Å
366	A	48.4	Very low	49.9	Very low	83 Å²	83	114.9 Å²	114.9	69%	0.686	63%	0.625	S	S	*	*			trans	-57.8	95.6	163	0	0	0	0	0	105.4	R364 I368	R364-A366 PolarHBondContact O-N 2.9Å; A366-I368 HydrophobicContact CB-CG1 4.02Å; A366-I368 PolarHBondContact O-N 3.31Å
367	V	46.7	Very low	49.5	Very low	131 Å²	131	118.5 Å²	118.5	79%	0.794	65%	0.646	S	S	*	*			trans	-70.8	84.2	162.1	-177.2	0	0	0	0	103.2	P365 A369	P365-V367 HydrophobicContact CG-CG2 4.45Å; P365-V367 PolarHBondContact O-N 2.85Å; V367-A369 PolarHBondContact O-N 3.06Å
368	I	44.8	Very low	49.3	Very low	152 Å²	152	123.4 Å²	123.4	78%	0.779	67%	0.665	S	S	*	*			trans	-65.2	114.7	167.1	-61.9	173.7	0	0	0	104.1	A366	A366-I368 HydrophobicContact CB-CG1 4.02Å; A366-I368 PolarHBondContact O-N 3.31Å
369	A	41.8	Very low	49	Very low	161 Å²	161	131.6 Å²	131.6	100%	1.331	71%	0.706	S	S	*	*			trans	-64.9	0	174.8	0	0	0	0	0	111.6	V367	V367-A369 PolarHBondContact O-N 3.06Å

Retrieved 369 of 369 residues in 390.8 ms (Link to these results)

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