A0A087YMF5_POEFO Loading...

Serine/threonine-protein kinase Nek2

AlphaFold DB , UniProt , Accession A0A087YMF5, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 440 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M47.2Very low86.8Confident207 Ų20786.8 Ų86.8100%1.0244%0.444SS*.  0151.10-72.4-155.6172.500108.4S3M1-S3 PolarHBondContact O-N 2.86Å
2P70.3Confident87.5Confident112 Ų11288.8 Ų88.873%0.72744%0.444SS*.  trans-60.4135.6168.825.8-31.5000109
3S80.9Confident88Confident38 Ų3886.6 Ų86.627%0.26644%0.438SS..  trans-63.2145.2178.2-48.70000110.6M1 D7 D72M1-S3 PolarHBondContact O-N 2.86Å; S3-D7 WeakPolarHBondContact CA-OD2 3.43Å; S3-D72 WeakPolarHBondContact CB-OD2 3.38Å; S3-D72 PolarHBondContact OG-OD2 3.16Å
4R90Very high88Confident138 Ų13886.4 Ų86.452%0.52144%0.437SS..  trans-116165.4-176.8-55.2-176.5179.8179.7-0.8110.8E6 D7R4-E6 WeakPolarHBondContact CB-OE2 3.39Å; R4-E6 VanDerWaalsContact CD-OE2 3.29Å; R4-E6 WeakPolarHBondContact CD-OE2 3.13Å; R4-E6 PolarHBondContact O-N 3.17Å; R4-D7 PolarHBondContact N-OD2 3.25Å; R4-D7 WeakPolarHBondContact O-CB 3.37Å; R4-D7 PolarHBondContact O-N 3.42Å
5V91.6Very high87.6Confident37 Ų3782.8 Ų82.822%0.22443%0.43CS..G310 helixtrans-60.9-38.5177.5-1790000109.6D7 Y8 W36 I74 D76 Y83V5-D7 PolarHBondContact O-N 3.41Å; V5-D7 VanDerWaalsContact O-N 3.14Å; V5-Y8 PolarHBondContact O-N 2.96Å; V5-Y8 VanDerWaalsContact O-N 3.12Å; V5-W36 HydrophobicContact CG1-CH2 3.75Å; V5-W36 HydrophobicContact CG1-CZ3 4.31Å; V5-I74 HydrophobicContact CG2-CG2 3.7Å; V5-D76 HydrophobicContact CG2-CB 4.37Å; V5-Y83 HydrophobicContact CG2-CD2 4.31Å; V5-Y83 HydrophobicContact CG2-CE2 3.95Å
6E93.1Very high86.9Confident129 Ų12983.6 Ų83.660%0.60345%0.445SS*.G310 helixtrans-65.1-13.8179.2-47.380.3-119.200114.6R4 Y8 N28R4-E6 WeakPolarHBondContact CB-OE2 3.39Å; R4-E6 VanDerWaalsContact CD-OE2 3.29Å; R4-E6 WeakPolarHBondContact CD-OE2 3.13Å; R4-E6 PolarHBondContact O-N 3.17Å; E6-Y8 PolarHBondContact O-N 2.91Å; E6-N28 PolarHBondContact O-ND2 2.95Å
7D94.6Very high85.6Confident70 Ų7081.8 Ų81.837%0.37445%0.451SS..G310 helixtrans-75.2-5.6175.1-62.6-34.4000112.3S3 R4 V5 N28S3-D7 WeakPolarHBondContact CA-OD2 3.43Å; R4-D7 PolarHBondContact N-OD2 3.25Å; R4-D7 WeakPolarHBondContact O-CB 3.37Å; R4-D7 PolarHBondContact O-N 3.42Å; V5-D7 PolarHBondContact O-N 3.41Å; V5-D7 VanDerWaalsContact O-N 3.14Å; D7-N28 WeakPolarHBondContact O-CB 3.4Å; D7-N28 PolarHBondContact O-N 2.82Å
8Y96.3Very high83.9Confident17 Ų1782.8 Ų82.87%0.06747%0.465CS..EExtended strand (participates in β ladder)trans-132.1139.1-175.9-57.9-94.1000111.7V5 E6 I25 R26 R27 L34 W36 D72 I74 V85V5-Y8 PolarHBondContact O-N 2.96Å; V5-Y8 VanDerWaalsContact O-N 3.12Å; E6-Y8 PolarHBondContact O-N 2.91Å; Y8-I25 HydrophobicContact CD1-CD1 3.48Å; Y8-I25 VanDerWaalsContact CD1-CD1 3.48Å; Y8-I25 HydrophobicContact CD1-CG1 4.1Å; Y8-I25 HydrophobicContact CE1-CD1 4.08Å; Y8-I25 HydrophobicContact CG-CD1 3.94Å; Y8-R26 CarbonylContact C-O 3.46Å; Y8-R26 VanDerWaalsContact CA-O 3.32Å; Y8-R26 WeakPolarHBondContact CA-O 3.23Å; Y8-R27 HydrophobicContact CD1-CB 3.84Å; Y8-R27 HydrophobicContact CD1-CG 4.13Å; Y8-R27 HydrophobicContact CE1-CB 3.73Å; Y8-R27 HydrophobicContact CE1-CG 3.74Å; Y8-L34 HydrophobicContact CE1-CD1 4.03Å; Y8-W36 HydrophobicContact CD2-CZ3 4.33Å; Y8-W36 HydrophobicContact CG-CZ3 4.29Å; Y8-D72 PolarHBondContact OH-OD2 3.18Å; Y8-I74 HydrophobicContact CD2-CD1 3.6Å; Y8-I74 HydrophobicContact CE2-CD1 3.47Å; Y8-I74 VanDerWaalsContact CE2-CD1 3.47Å; Y8-I74 HydrophobicContact CE2-CG1 4.4Å; Y8-V85 HydrophobicContact CE1-CG1 4.19Å
9E96.8Very high82.7Confident88 Ų8881 Ų8141%0.41145%0.45SS..EExtended strand (participates in β ladder)trans-97.2122.9170.9-178.8-167-176.700109.2L11 I25 R26E9-L11 HydrophobicContact CG-CD2 4.27Å; E9-I25 CarbonylContact O-C 3.59Å; E9-I25 VanDerWaalsContact O-CA 3.24Å; E9-I25 WeakPolarHBondContact O-CA 3.44Å; E9-R26 HydrophobicContact CB-CB 4.36Å; E9-R26 PolarHBondContact N-O 2.8Å; E9-R26 PolarHBondContact O-N 2.71Å; E9-R26 IonicContact OE1-NH1 2.69Å; E9-R26 IonicContact OE2-CZ 2.8Å; E9-R26 IonicContact OE2-NH1 3.41Å; E9-R26 PolarHBondContact OE2-NH1 3.09Å
10V96.8Very high82.3Confident64 Ų6478.4 Ų78.439%0.38844%0.443SS..EExtended strand (participates in β ladder)trans-76.4124.3173.1-178.50000109.5Q23 I25 W36V10-Q23 HydrophobicContact CG1-CB 4.24Å; V10-I25 HydrophobicContact CG2-CG2 4.29Å; V10-W36 HydrophobicContact CG2-CH2 3.93Å; V10-W36 HydrophobicContact CG2-CZ2 3.29Å
11L97Very high82.4Confident55 Ų5579.9 Ų79.929%0.28844%0.441SS..EExtended strand (participates in β ladder)trans-91.5-58.1178.9-56.5-178.3000111.2E9 K24 R26 I33E9-L11 HydrophobicContact CG-CD2 4.27Å; L11-K24 WeakPolarHBondContact CB-O 3.5Å; L11-K24 HydrophobicContact CD1-CD 4.35Å; L11-K24 HydrophobicContact CD1-CG 4.25Å; L11-K24 PolarHBondContact N-O 2.97Å; L11-R26 HydrophobicContact CD1-CB 4.33Å; L11-R26 HydrophobicContact CD2-CB 4.25Å; L11-R26 HydrophobicContact CG-CB 4.39Å; L11-I33 HydrophobicContact CD1-CD1 3.95Å
12Y94.9Very high84.5Confident111 Ų11171.8 Ų71.844%0.43541%0.405SS..EExtended strand (participates in β ladder)trans-163.6160.6176.860.2-92.2000111.8I14 Q23 K24Y12-I14 HydrophobicContact CD2-CG1 4.46Å; Y12-I14 HydrophobicContact CE2-CG1 4.05Å; Y12-Q23 WeakPolarHBondContact O-CA 3.24Å; Y12-K24 HydrophobicContact CD1-CB 4.45Å; Y12-K24 HydrophobicContact CD1-CD 4.33Å; Y12-K24 HydrophobicContact CE1-CB 4.24Å; Y12-K24 HydrophobicContact CE1-CD 3.44Å; Y12-K24 VanDerWaalsContact CE1-CD 3.44Å; Y12-K24 HydrophobicContact CE1-CG 4.45Å; Y12-K24 HydrophobicContact CE2-CB 4.33Å; Y12-K24 HydrophobicContact CE2-CD 4.31Å; Y12-K24 VanDerWaalsContact CZ-CD 3.42Å; Y12-K24 PolarHBondContact O-N 3.06Å; Y12-K24 VanDerWaalsContact OH-CD 3.25Å; Y12-K24 WeakPolarHBondContact OH-CD 3.34Å; Y12-K24 PolarHBondContact OH-NZ 3.32Å
13T93.9Very high85.6Confident60 Ų6067.1 Ų67.137%0.36837%0.373SS..EExtended strand (participates in β ladder)trans-79.6123174.3-58.30000110.2R21 Q23T13-R21 HydrophobicContact CG2-CB 4.31Å; T13-Q23 HydrophobicContact CG2-CG 4.5Å; T13-Q23 PolarHBondContact OG1-NE2 3.21Å
14I88.6Confident86.3Confident84 Ų8466.8 Ų66.843%0.43137%0.367SS..EExtended strand (participates in β ladder)trans-78.9-41176.7-60.7170.8000110Y12 C22 K24 V35 Y88Y12-I14 HydrophobicContact CD2-CG1 4.46Å; Y12-I14 HydrophobicContact CE2-CG1 4.05Å; I14-C22 PolarHBondContact N-O 3.45Å; I14-K24 HydrophobicContact CD1-CB 3.97Å; I14-K24 HydrophobicContact CG1-CB 4.06Å; I14-V35 HydrophobicContact CD1-CB 4.45Å; I14-V35 HydrophobicContact CD1-CG1 3.47Å; I14-V35 VanDerWaalsContact CD1-CG1 3.47Å; I14-Y88 HydrophobicContact CD1-CD2 4.27Å; I14-Y88 HydrophobicContact CD1-CE2 4.05Å
15G81.6Confident86.7Confident32 Ų3260.2 Ų60.233%0.3334%0.342SS..EExtended strand (participates in β ladder)trans-168.6156.1178.400000112C22G15-C22 PolarHBondContact N-O 3.46Å; G15-C22 PolarHBondContact O-N 2.91Å
16S76.3Confident87Confident95 Ų9562.9 Ų62.966%0.66435%0.348SS*.EExtended strand (participates in β ladder)trans-109.7110.4173.7-60.70000107.8
17G65.3Low87.1Confident53 Ų5359.4 Ų59.455%0.54633%0.33SS..EExtended strand (participates in β ladder)trans-91.8176.5174.400000111.3Y19 G20G17-Y19 PolarHBondContact O-N 3.19Å; G17-G20 PolarHBondContact N-O 3.36Å; G17-G20 PolarHBondContact O-N 3.12Å
18S54.8Low87.2Confident101 Ų10160.5 Ų60.571%0.70634%0.335SS*.THydrogen-bonded Turntrans-62.9-13.5179.4-30.90000114.4
19Y61Low87.2Confident48 Ų4864.5 Ų64.519%0.18837%0.366CS..THydrogen-bonded Turntrans-123.58.7-172.3-50.9-82.2000113.4G17 E38 L166 T170 K174G17-Y19 PolarHBondContact O-N 3.19Å; Y19-E38 VanDerWaalsContact O-O 3.14Å; Y19-L166 HydrophobicContact CD1-CB 4.44Å; Y19-L166 HydrophobicContact CD1-CD1 3.64Å; Y19-L166 HydrophobicContact CD1-CD2 3.43Å; Y19-L166 VanDerWaalsContact CD1-CD2 3.43Å; Y19-L166 HydrophobicContact CD1-CG 4.01Å; Y19-L166 HydrophobicContact CD2-CD1 3.71Å; Y19-L166 HydrophobicContact CE1-CB 3.87Å; Y19-L166 HydrophobicContact CE1-CD1 3.81Å; Y19-L166 HydrophobicContact CE1-CD2 3.63Å; Y19-L166 HydrophobicContact CE1-CG 3.96Å; Y19-L166 HydrophobicContact CE2-CD1 3.92Å; Y19-L166 HydrophobicContact CG-CD1 3.55Å; Y19-L166 HydrophobicContact CG-CD2 4.14Å; Y19-L166 HydrophobicContact CG-CG 4.41Å; Y19-T170 HydrophobicContact CE1-CG2 4.29Å; Y19-T170 WeakPolarHBondContact CE1-OG1 3.42Å; Y19-T170 PolarHBondContact OH-OG1 2.66Å; Y19-K174 HydrophobicContact CE2-CD 4.39Å; Y19-K174 VanDerWaalsContact OH-CD 3.26Å; Y19-K174 WeakPolarHBondContact OH-CD 3.5Å; Y19-K174 WeakPolarHBondContact OH-CE 3.2Å; Y19-K174 PolarHBondContact OH-NZ 3.24Å
20G74.3Confident87.1Confident29 Ų2964.4 Ų64.430%0.29937%0.368SS..EExtended strand (participates in β ladder)trans136.9-177.3-179.400000113G17 E38G17-G20 PolarHBondContact N-O 3.36Å; G17-G20 PolarHBondContact O-N 3.12Å; G20-E38 WeakPolarHBondContact CA-O 3.45Å
21R85.9Confident87Confident109 Ų10963.2 Ų63.241%0.41137%0.369SS..EExtended strand (participates in β ladder)trans-93.6141.9-176.1-61.7176.2-63.5175.26110.5T13 Q23 E38T13-R21 HydrophobicContact CG2-CB 4.31Å; R21-Q23 HydrophobicContact CB-CG 4.14Å; R21-E38 HydrophobicContact CB-CG 4.47Å; R21-E38 IonicContact CZ-OE1 3.41Å; R21-E38 IonicContact CZ-OE2 3.31Å; R21-E38 VanDerWaalsContact CZ-OE2 3.26Å; R21-E38 IonicContact NE-OE1 3.17Å; R21-E38 IonicContact NE-OE2 2.75Å; R21-E38 PolarHBondContact NE-OE2 3.2Å; R21-E38 VanDerWaalsContact NH2-CD 3.32Å; R21-E38 IonicContact NH2-OE1 3.42Å; R21-E38 PolarHBondContact NH2-OE1 3.22Å; R21-E38 IonicContact NH2-OE2 3.16Å; R21-E38 PolarHBondContact NH2-OE2 3.42Å; R21-E38 PolarHBondContact O-N 2.94Å
22C89.6Confident87Confident38 Ų3864.2 Ų64.226%0.25737%0.371SS..EExtended strand (participates in β ladder)trans-99.5119.8163.5-173.50000107.3I14 G15 W36I14-C22 PolarHBondContact N-O 3.45Å; G15-C22 PolarHBondContact N-O 3.46Å; G15-C22 PolarHBondContact O-N 2.91Å; C22-W36 WeakPolarHBondContact CA-O 2.82Å
23Q94.6Very high87.1Confident14 Ų1461.3 Ų61.37%0.06536%0.363CS..EExtended strand (participates in β ladder)trans-122.9143.6-178.6-51.2-173.7-49.800110.7V10 Y12 T13 R21 V35 W36 E38V10-Q23 HydrophobicContact CG1-CB 4.24Å; Y12-Q23 WeakPolarHBondContact O-CA 3.24Å; T13-Q23 HydrophobicContact CG2-CG 4.5Å; T13-Q23 PolarHBondContact OG1-NE2 3.21Å; R21-Q23 HydrophobicContact CB-CG 4.14Å; Q23-V35 CarbonylContact O-C 3.51Å; Q23-V35 WeakPolarHBondContact O-CA 3.29Å; Q23-W36 PolarHBondContact N-O 3.09Å; Q23-W36 PolarHBondContact O-N 3Å; Q23-E38 PolarHBondContact OE1-OE1 3.34Å
24K95.9Very high87.2Confident31 Ų3158.5 Ų58.514%0.13535%0.345CS..EExtended strand (participates in β ladder)trans-79.8129.4169.5-166.6177.6-179169.10108.4L11 Y12 I14 I33 Y88L11-K24 WeakPolarHBondContact CB-O 3.5Å; L11-K24 HydrophobicContact CD1-CD 4.35Å; L11-K24 HydrophobicContact CD1-CG 4.25Å; L11-K24 PolarHBondContact N-O 2.97Å; Y12-K24 HydrophobicContact CD1-CB 4.45Å; Y12-K24 HydrophobicContact CD1-CD 4.33Å; Y12-K24 HydrophobicContact CE1-CB 4.24Å; Y12-K24 HydrophobicContact CE1-CD 3.44Å; Y12-K24 VanDerWaalsContact CE1-CD 3.44Å; Y12-K24 HydrophobicContact CE1-CG 4.45Å; Y12-K24 HydrophobicContact CE2-CB 4.33Å; Y12-K24 HydrophobicContact CE2-CD 4.31Å; Y12-K24 VanDerWaalsContact CZ-CD 3.42Å; Y12-K24 PolarHBondContact O-N 3.06Å; Y12-K24 VanDerWaalsContact OH-CD 3.25Å; Y12-K24 WeakPolarHBondContact OH-CD 3.34Å; Y12-K24 PolarHBondContact OH-NZ 3.32Å; I14-K24 HydrophobicContact CD1-CB 3.97Å; I14-K24 HydrophobicContact CG1-CB 4.06Å; K24-I33 HydrophobicContact CD-CG2 4.2Å; K24-I33 HydrophobicContact CG-CG2 3.99Å; K24-Y88 HydrophobicContact CD-CE1 4.19Å; K24-Y88 HydrophobicContact CD-CE2 4.21Å; K24-Y88 HydrophobicContact CG-CE2 4.49Å; K24-Y88 PolarHBondContact NZ-OH 3.05Å; K24-Y88 VanDerWaalsContact NZ-OH 3.17Å
25I97.4Very high87.5Confident0 Ų055 Ų550%033%0.328CS..EExtended strand (participates in β ladder)trans-128.8156.2-177.768.9-179.1000110.7Y8 E9 V10 L34 W36 V85Y8-I25 HydrophobicContact CD1-CD1 3.48Å; Y8-I25 VanDerWaalsContact CD1-CD1 3.48Å; Y8-I25 HydrophobicContact CD1-CG1 4.1Å; Y8-I25 HydrophobicContact CE1-CD1 4.08Å; Y8-I25 HydrophobicContact CG-CD1 3.94Å; E9-I25 CarbonylContact O-C 3.59Å; E9-I25 VanDerWaalsContact O-CA 3.24Å; E9-I25 WeakPolarHBondContact O-CA 3.44Å; V10-I25 HydrophobicContact CG2-CG2 4.29Å; I25-L34 HydrophobicContact CD1-CB 4.31Å; I25-L34 HydrophobicContact CG1-CB 3.84Å; I25-L34 PolarHBondContact N-O 3.02Å; I25-L34 PolarHBondContact O-N 3.09Å; I25-L34 VanDerWaalsContact O-O 3.12Å; I25-W36 HydrophobicContact CD1-CB 3.99Å; I25-W36 HydrophobicContact CD1-CD2 3.78Å; I25-W36 HydrophobicContact CD1-CE3 3.59Å; I25-W36 HydrophobicContact CD1-CG 3.96Å; I25-W36 HydrophobicContact CD1-CZ3 4.35Å; I25-W36 HydrophobicContact CG2-CD2 3.65Å; I25-W36 HydrophobicContact CG2-CE3 4.21Å; I25-W36 HydrophobicContact CG2-CG 3.88Å; I25-W36 HydrophobicContact CG2-CZ2 4.1Å; I25-V85 HydrophobicContact CD1-CG1 4.08Å; I25-V85 HydrophobicContact CD1-CG2 4.45Å
26R97.6Very high88Confident93 Ų9353.7 Ų53.735%0.35131%0.313SS..EExtended strand (participates in β ladder)trans-114.4127.3170.5179.9-176.5-65.2135.5-4.2108.5Y8 E9 L11 K32 I33Y8-R26 CarbonylContact C-O 3.46Å; Y8-R26 VanDerWaalsContact CA-O 3.32Å; Y8-R26 WeakPolarHBondContact CA-O 3.23Å; E9-R26 HydrophobicContact CB-CB 4.36Å; E9-R26 PolarHBondContact N-O 2.8Å; E9-R26 PolarHBondContact O-N 2.71Å; E9-R26 IonicContact OE1-NH1 2.69Å; E9-R26 IonicContact OE2-CZ 2.8Å; E9-R26 IonicContact OE2-NH1 3.41Å; E9-R26 PolarHBondContact OE2-NH1 3.09Å; L11-R26 HydrophobicContact CD1-CB 4.33Å; L11-R26 HydrophobicContact CD2-CB 4.25Å; L11-R26 HydrophobicContact CG-CB 4.39Å; R26-K32 WeakPolarHBondContact CA-O 3.39Å; R26-I33 HydrophobicContact CB-CD1 4.09Å; R26-I33 HydrophobicContact CG-CD1 4.19Å
27R96.8Very high88.7Confident56 Ų5651.1 Ų51.121%0.21129%0.29CS..EExtended strand (participates in β ladder)trans-77.4128.7174-175.816960.5-179.93110.1Y8 S29 D30 G31 K32 L34Y8-R27 HydrophobicContact CD1-CB 3.84Å; Y8-R27 HydrophobicContact CD1-CG 4.13Å; Y8-R27 HydrophobicContact CE1-CB 3.73Å; Y8-R27 HydrophobicContact CE1-CG 3.74Å; R27-S29 VanDerWaalsContact C-N 3.32Å; R27-S29 WeakPolarHBondContact CG-OG 3.37Å; R27-S29 PolarHBondContact O-N 3.08Å; R27-D30 IonicContact CZ-OD1 3.56Å; R27-D30 IonicContact CZ-OD2 3.81Å; R27-D30 IonicContact NE-OD1 2.75Å; R27-D30 PolarHBondContact NE-OD1 3.19Å; R27-D30 IonicContact NE-OD2 3.99Å; R27-D30 VanDerWaalsContact NH2-CG 3.3Å; R27-D30 IonicContact NH2-OD1 2.78Å; R27-D30 PolarHBondContact NH2-OD1 3.17Å; R27-D30 IonicContact NH2-OD2 3.68Å; R27-D30 PolarHBondContact NH2-OD2 3.31Å; R27-G31 VanDerWaalsContact O-CA 3.23Å; R27-G31 WeakPolarHBondContact O-CA 3.43Å; R27-G31 PolarHBondContact O-N 3.31Å; R27-K32 PolarHBondContact N-O 2.86Å; R27-L34 HydrophobicContact CB-CD1 4.29Å
28N96.4Very high89.8Confident92 Ų9249.4 Ų49.449%0.49227%0.268SS..THydrogen-bonded Turntrans-69.2-28.9-172.6-67.6-16.9000113.2E6 D7 D30E6-N28 PolarHBondContact O-ND2 2.95Å; D7-N28 WeakPolarHBondContact O-CB 3.4Å; D7-N28 PolarHBondContact O-N 2.82Å; N28-D30 PolarHBondContact O-N 3.3Å
29S95.3Very high91.3Very high101 Ų10144.7 Ų44.771%0.70624%0.235SC*.THydrogen-bonded Turntrans-70.6-30-175.557.20000114.7R27R27-S29 VanDerWaalsContact C-N 3.32Å; R27-S29 WeakPolarHBondContact CG-OG 3.37Å; R27-S29 PolarHBondContact O-N 3.08Å
30D95.5Very high92.5Very high87 Ų8746.2 Ų46.247%0.46525%0.246SC..THydrogen-bonded Turntrans-140.56.5-176.369.5-19.7000114.3R27 N28 K32R27-D30 IonicContact CZ-OD1 3.56Å; R27-D30 IonicContact CZ-OD2 3.81Å; R27-D30 IonicContact NE-OD1 2.75Å; R27-D30 PolarHBondContact NE-OD1 3.19Å; R27-D30 IonicContact NE-OD2 3.99Å; R27-D30 VanDerWaalsContact NH2-CG 3.3Å; R27-D30 IonicContact NH2-OD1 2.78Å; R27-D30 PolarHBondContact NH2-OD1 3.17Å; R27-D30 IonicContact NH2-OD2 3.68Å; R27-D30 PolarHBondContact NH2-OD2 3.31Å; N28-D30 PolarHBondContact O-N 3.3Å; D30-K32 PolarHBondContact O-N 3.49Å; D30-K32 WeakPolarHBondContact OD1-CB 3.44Å; D30-K32 PolarHBondContact OD1-N 3.32Å
31G95.4Very high93.1Very high39 Ų3946.8 Ų46.840%0.40224%0.239SC..  trans67.810.5-177.900000114.1R27 I33R27-G31 VanDerWaalsContact O-CA 3.23Å; R27-G31 WeakPolarHBondContact O-CA 3.43Å; R27-G31 PolarHBondContact O-N 3.31Å; G31-I33 PolarHBondContact O-N 3.39Å
32K95.9Very high93Very high76 Ų7643.4 Ų43.433%0.3324%0.238SC..  trans-68.8131.3-174.1-174.4168.7-175.8161.40111.7R26 R27 D30 L34 Y71R26-K32 WeakPolarHBondContact CA-O 3.39Å; R27-K32 PolarHBondContact N-O 2.86Å; D30-K32 PolarHBondContact O-N 3.49Å; D30-K32 WeakPolarHBondContact OD1-CB 3.44Å; D30-K32 PolarHBondContact OD1-N 3.32Å; K32-L34 HydrophobicContact CD-CD2 4.35Å; K32-L34 HydrophobicContact CG-CD2 4.27Å; K32-L34 HydrophobicContact CG-CG 4.26Å; K32-Y71 HydrophobicContact CD-CE1 4.44Å; K32-Y71 VanDerWaalsContact CE-OH 3.3Å; K32-Y71 WeakPolarHBondContact CE-OH 3.24Å; K32-Y71 PolarHBondContact NZ-OH 2.95Å
33I96.8Very high92.6Very high50 Ų5047.6 Ų47.626%0.25626%0.263SS..EExtended strand (participates in β ladder)trans-80.3127.6175.7-55.3-56.4000110.1L11 K24 R26 G31 Y88L11-I33 HydrophobicContact CD1-CD1 3.95Å; K24-I33 HydrophobicContact CD-CG2 4.2Å; K24-I33 HydrophobicContact CG-CG2 3.99Å; R26-I33 HydrophobicContact CB-CD1 4.09Å; R26-I33 HydrophobicContact CG-CD1 4.19Å; G31-I33 PolarHBondContact O-N 3.39Å; I33-Y88 HydrophobicContact CG2-CD1 3.48Å; I33-Y88 VanDerWaalsContact CG2-CD1 3.48Å; I33-Y88 HydrophobicContact CG2-CE1 4.12Å; I33-Y88 HydrophobicContact CG2-CG 3.98Å
34L95.9Very high92Very high0 Ų048.2 Ų48.20%027%0.266CS..EExtended strand (participates in β ladder)trans-139.1177.6-177.4-63.9169.9000109.3Y8 I25 R27 K32 Y71 V85Y8-L34 HydrophobicContact CE1-CD1 4.03Å; I25-L34 HydrophobicContact CD1-CB 4.31Å; I25-L34 HydrophobicContact CG1-CB 3.84Å; I25-L34 PolarHBondContact N-O 3.02Å; I25-L34 PolarHBondContact O-N 3.09Å; I25-L34 VanDerWaalsContact O-O 3.12Å; R27-L34 HydrophobicContact CB-CD1 4.29Å; K32-L34 HydrophobicContact CD-CD2 4.35Å; K32-L34 HydrophobicContact CG-CD2 4.27Å; K32-L34 HydrophobicContact CG-CG 4.26Å; L34-Y71 HydrophobicContact CD2-CD1 4.25Å; L34-Y71 HydrophobicContact CD2-CD2 3.72Å; L34-Y71 HydrophobicContact CD2-CE1 4.24Å; L34-Y71 HydrophobicContact CD2-CE2 3.7Å; L34-Y71 HydrophobicContact CD2-CG 4Å; L34-V85 HydrophobicContact CB-CG1 4.1Å; L34-V85 HydrophobicContact CD1-CG1 3.75Å; L34-V85 HydrophobicContact CG-CG1 4.44Å
35V94.6Very high91.4Very high12 Ų1249 Ų497%0.07328%0.279CS..EExtended strand (participates in β ladder)trans-122.8150.6164.9-59.80000109.4I14 Q23 V85 M86 Y88I14-V35 HydrophobicContact CD1-CB 4.45Å; I14-V35 HydrophobicContact CD1-CG1 3.47Å; I14-V35 VanDerWaalsContact CD1-CG1 3.47Å; Q23-V35 CarbonylContact O-C 3.51Å; Q23-V35 WeakPolarHBondContact O-CA 3.29Å; V35-V85 CarbonylContact O-C 3.59Å; V35-V85 WeakPolarHBondContact O-CA 3.48Å; V35-M86 HydrophobicContact CG2-CB 3.88Å; V35-M86 HydrophobicContact CG2-CE 4.27Å; V35-M86 PolarHBondContact N-O 2.85Å; V35-M86 PolarHBondContact O-N 3.46Å; V35-Y88 HydrophobicContact CG1-CD2 3.47Å; V35-Y88 VanDerWaalsContact CG1-CD2 3.47Å; V35-Y88 HydrophobicContact CG1-CE2 4.41Å; V35-Y88 HydrophobicContact CG1-CG 4.13Å
36W93.8Very high90.8Very high4 Ų455.5 Ų55.52%0.01531%0.309CS..EExtended strand (participates in β ladder)trans-118.3150.5159.161.626.3000111.3V5 Y8 V10 C22 Q23 I25 I74 Y83 I84 V85V5-W36 HydrophobicContact CG1-CH2 3.75Å; V5-W36 HydrophobicContact CG1-CZ3 4.31Å; Y8-W36 HydrophobicContact CD2-CZ3 4.33Å; Y8-W36 HydrophobicContact CG-CZ3 4.29Å; V10-W36 HydrophobicContact CG2-CH2 3.93Å; V10-W36 HydrophobicContact CG2-CZ2 3.29Å; C22-W36 WeakPolarHBondContact CA-O 2.82Å; Q23-W36 PolarHBondContact N-O 3.09Å; Q23-W36 PolarHBondContact O-N 3Å; I25-W36 HydrophobicContact CD1-CB 3.99Å; I25-W36 HydrophobicContact CD1-CD2 3.78Å; I25-W36 HydrophobicContact CD1-CE3 3.59Å; I25-W36 HydrophobicContact CD1-CG 3.96Å; I25-W36 HydrophobicContact CD1-CZ3 4.35Å; I25-W36 HydrophobicContact CG2-CD2 3.65Å; I25-W36 HydrophobicContact CG2-CE3 4.21Å; I25-W36 HydrophobicContact CG2-CG 3.88Å; I25-W36 HydrophobicContact CG2-CZ2 4.1Å; W36-I74 HydrophobicContact CE3-CD1 4.01Å; W36-I74 HydrophobicContact CZ3-CD1 3.93Å; W36-Y83 AromaticContact CD2-CD1 3.5Å; W36-Y83 HydrophobicContact CD2-CD1 3.5Å; W36-Y83 VanDerWaalsContact CD2-CD1 3.5Å; W36-Y83 HydrophobicContact CD2-CE1 4.2Å; W36-Y83 HydrophobicContact CD2-CG 4.19Å; W36-Y83 AromaticContact CE2-CD1 3.58Å; W36-Y83 AromaticContact CE2-CE1 3.8Å; W36-Y83 AromaticContact CE3-CD1 3.81Å; W36-Y83 HydrophobicContact CE3-CD1 3.81Å; W36-Y83 HydrophobicContact CE3-CG 4.1Å; W36-Y83 AromaticContact CG-CD1 3.87Å; W36-Y83 HydrophobicContact CG-CD1 3.87Å; W36-Y83 HydrophobicContact CH2-CD1 4.31Å; W36-Y83 HydrophobicContact CH2-CE1 4.29Å; W36-Y83 AromaticContact CZ2-CD1 3.97Å; W36-Y83 HydrophobicContact CZ2-CD1 3.97Å; W36-Y83 AromaticContact CZ2-CE1 3.83Å; W36-Y83 HydrophobicContact CZ2-CE1 3.83Å; W36-Y83 HydrophobicContact CZ3-CD1 4.22Å; W36-Y83 HydrophobicContact CZ3-CG 4.48Å; W36-Y83 AromaticContact NE1-CD1 3.93Å; W36-I84 CarbonylContact C-O 3.52Å; W36-I84 VanDerWaalsContact CA-O 3.23Å; W36-I84 WeakPolarHBondContact CA-O 3.44Å; W36-V85 HydrophobicContact CB-CG2 4.32Å
37K89.9Confident89.9Confident41 Ų4154.9 Ų54.918%0.17832%0.319CS..EExtended strand (participates in β ladder)trans-107.6121.7168.8-168.8166.7177.7171.80107.4L39 Y83 I84 M86 D159 L162K37-L39 HydrophobicContact CG-CD1 4.32Å; K37-Y83 WeakPolarHBondContact O-CA 3.49Å; K37-I84 PolarHBondContact N-O 3.44Å; K37-I84 PolarHBondContact O-N 2.84Å; K37-M86 HydrophobicContact CB-CE 4.01Å; K37-M86 HydrophobicContact CD-CE 4.5Å; K37-D159 IonicContact NZ-OD1 3.75Å; K37-D159 PolarHBondContact NZ-OD1 2.85Å; K37-D159 IonicContact NZ-OD2 3.58Å; K37-D159 PolarHBondContact NZ-OD2 3.42Å; K37-L162 HydrophobicContact CD-CD1 3.74Å
38E89.4Confident89.1Confident17 Ų1754.1 Ų54.18%0.07932%0.318CS..EExtended strand (participates in β ladder)trans-81.1137.2175.7-58.3-178.7177.500109.6Y19 G20 R21 Q23 T81 L82 Y83Y19-E38 VanDerWaalsContact O-O 3.14Å; G20-E38 WeakPolarHBondContact CA-O 3.45Å; R21-E38 HydrophobicContact CB-CG 4.47Å; R21-E38 IonicContact CZ-OE1 3.41Å; R21-E38 IonicContact CZ-OE2 3.31Å; R21-E38 VanDerWaalsContact CZ-OE2 3.26Å; R21-E38 IonicContact NE-OE1 3.17Å; R21-E38 IonicContact NE-OE2 2.75Å; R21-E38 PolarHBondContact NE-OE2 3.2Å; R21-E38 VanDerWaalsContact NH2-CD 3.32Å; R21-E38 IonicContact NH2-OE1 3.42Å; R21-E38 PolarHBondContact NH2-OE1 3.22Å; R21-E38 IonicContact NH2-OE2 3.16Å; R21-E38 PolarHBondContact NH2-OE2 3.42Å; R21-E38 PolarHBondContact O-N 2.94Å; Q23-E38 PolarHBondContact OE1-OE1 3.34Å; E38-T81 HydrophobicContact CB-CG2 4.31Å; E38-L82 CarbonylContact C-O 3.54Å; E38-Y83 HydrophobicContact CB-CE1 4.49Å; E38-Y83 HydrophobicContact CG-CD1 3.72Å; E38-Y83 HydrophobicContact CG-CE1 3.54Å
39L86.1Confident88.4Confident2 Ų252.6 Ų52.61%0.0131%0.307CS..EExtended strand (participates in β ladder)trans-136.5121.7173.1-68.7100.4000109.8K37 L52 T81 L82 I84 L162K37-L39 HydrophobicContact CG-CD1 4.32Å; L39-L52 HydrophobicContact CD2-CD1 4.38Å; L39-T81 CarbonylContact O-C 3.59Å; L39-T81 WeakPolarHBondContact O-CA 3.29Å; L39-L82 HydrophobicContact CB-CB 4.35Å; L39-L82 PolarHBondContact N-O 2.88Å; L39-L82 PolarHBondContact O-N 3.15Å; L39-I84 HydrophobicContact CD1-CD1 3.66Å; L39-I84 HydrophobicContact CD1-CG1 3.95Å; L39-L162 HydrophobicContact CD1-CD1 4.09Å; L39-L162 HydrophobicContact CD1-CD2 4.48Å; L39-L162 HydrophobicContact CD2-CD1 3.71Å; L39-L162 HydrophobicContact CD2-CD2 3.32Å; L39-L162 HydrophobicContact CD2-CG 4.12Å; L39-L162 HydrophobicContact CG-CD1 4.33Å
40D86.1Confident87.8Confident79 Ų7953.1 Ų53.142%0.42230%0.298SS..EExtended strand (participates in β ladder)trans-77.6121.8168.5-175.98000109.4G42 T80D40-G42 PolarHBondContact OD1-N 3.01Å; D40-T80 VanDerWaalsContact OD1-O 3.09Å; D40-T80 PolarHBondContact OD1-OG1 2.86Å
41Y85.6Confident87Confident41 Ų4151.6 Ų51.616%0.16129%0.289CS..  trans-106.42175.667.4-100.7000112.6T43 M44 K49 I75 R77 T80 L82Y41-T43 VanDerWaalsContact C-N 3.3Å; Y41-T43 PolarHBondContact O-N 3.28Å; Y41-M44 PolarHBondContact O-N 2.86Å; Y41-K49 WeakPolarHBondContact O-CE 3.15Å; Y41-I75 HydrophobicContact CE1-CG2 3.99Å; Y41-I75 WeakPolarHBondContact OH-CG2 3.47Å; Y41-R77 WeakPolarHBondContact OH-CA 3.25Å; Y41-T80 VanDerWaalsContact CD1-C 3.49Å; Y41-T80 WeakPolarHBondContact CD1-O 3.23Å; Y41-T80 VanDerWaalsContact CE1-O 3.29Å; Y41-T80 WeakPolarHBondContact CE1-O 3.37Å; Y41-T80 HydrophobicContact CE2-CG2 4.41Å; Y41-T80 PolarHBondContact N-O 3.2Å; Y41-L82 HydrophobicContact CD1-CB 4.01Å; Y41-L82 HydrophobicContact CE1-CB 4.49Å
42G85.4Confident86.3Confident38 Ų3850.2 Ų50.239%0.39227%0.272SS..THydrogen-bonded Turntrans-61.1-37.8-177.600000112.8D40D40-G42 PolarHBondContact OD1-N 3.01Å
43T80.8Confident85.7Confident127 Ų12749.7 Ų49.778%0.77928%0.275SS*.THydrogen-bonded Turntrans-88.4-5.4179.262.30000114.1Y41Y41-T43 VanDerWaalsContact C-N 3.3Å; Y41-T43 PolarHBondContact O-N 3.28Å
44M82Confident84.8Confident26 Ų2649.9 Ų49.913%0.12828%0.281CS..  trans-77.7138.4-176.2-69.7-176.8179.200111.8Y41 E48 K49 L52 L166Y41-M44 PolarHBondContact O-N 2.86Å; M44-E48 WeakPolarHBondContact CA-OE2 3.49Å; M44-E48 HydrophobicContact CB-CB 4.1Å; M44-E48 HydrophobicContact CG-CB 4.45Å; M44-K49 HydrophobicContact CB-CG 3.94Å; M44-K49 WeakPolarHBondContact O-CE 3.27Å; M44-K49 PolarHBondContact O-NZ 3.41Å; M44-L52 HydrophobicContact SD-CD2 4.04Å; M44-L166 HydrophobicContact CE-CD2 4.49Å
45A83.8Confident84Confident48 Ų4850.3 Ų50.340%0.39728%0.283SS..  trans-65.6158.3168.200000111.1S47 E48 K49A45-S47 PolarHBondContact O-N 3.17Å; A45-E48 HydrophobicContact CB-CG 4.26Å; A45-E48 PolarHBondContact N-OE2 3.46Å; A45-E48 WeakPolarHBondContact O-CB 3.47Å; A45-E48 PolarHBondContact O-N 2.88Å; A45-K49 PolarHBondContact O-N 2.89Å
46E83.6Confident83.5Confident136 Ų13649.8 Ų49.864%0.63628%0.28SS*.Hα-helixtrans-61.7-34.4-178.8-166.358.1-150.700112.5E48 K49 Q50E46-E48 PolarHBondContact O-N 2.59Å; E46-K49 PolarHBondContact O-N 3.18Å; E46-Q50 WeakPolarHBondContact O-CB 3.3Å; E46-Q50 PolarHBondContact O-N 2.69Å
47S79.4Confident83Confident81 Ų8151.9 Ų51.957%0.56629%0.291SS*.Hα-helixtrans-60.9-42.7172.348.90000112.1A45 Q50 M51A45-S47 PolarHBondContact O-N 3.17Å; S47-Q50 PolarHBondContact O-N 3.37Å; S47-M51 WeakPolarHBondContact O-CG 3.43Å; S47-M51 PolarHBondContact O-N 3.16Å
48E79.3Confident82.5Confident40 Ų4051.3 Ų51.319%0.18729%0.29CS..Hα-helixtrans-67.3-41.3178.2-62.8178.511900111.8M44 A45 E46 Q50 M51 L52 I165M44-E48 WeakPolarHBondContact CA-OE2 3.49Å; M44-E48 HydrophobicContact CB-CB 4.1Å; M44-E48 HydrophobicContact CG-CB 4.45Å; A45-E48 HydrophobicContact CB-CG 4.26Å; A45-E48 PolarHBondContact N-OE2 3.46Å; A45-E48 WeakPolarHBondContact O-CB 3.47Å; A45-E48 PolarHBondContact O-N 2.88Å; E46-E48 PolarHBondContact O-N 2.59Å; E48-Q50 VanDerWaalsContact C-N 3.34Å; E48-Q50 PolarHBondContact O-N 3.13Å; E48-M51 HydrophobicContact CB-CE 4.43Å; E48-M51 HydrophobicContact CG-CE 4.14Å; E48-M51 PolarHBondContact O-N 3.28Å; E48-L52 WeakPolarHBondContact O-CB 3.34Å; E48-L52 PolarHBondContact O-N 3.49Å; E48-I165 HydrophobicContact CB-CG2 4.28Å
49K82.8Confident82.2Confident60 Ų6051.6 Ų51.626%0.26129%0.292SS..Hα-helixtrans-60.6-43173.1-67.9175.2-173.8164.50111.7Y41 M44 A45 E46 M51 L52 V53Y41-K49 WeakPolarHBondContact O-CE 3.15Å; M44-K49 HydrophobicContact CB-CG 3.94Å; M44-K49 WeakPolarHBondContact O-CE 3.27Å; M44-K49 PolarHBondContact O-NZ 3.41Å; A45-K49 PolarHBondContact O-N 2.89Å; E46-K49 PolarHBondContact O-N 3.18Å; K49-M51 VanDerWaalsContact C-N 3.33Å; K49-M51 PolarHBondContact O-N 3.17Å; K49-L52 WeakPolarHBondContact O-CB 3.12Å; K49-L52 PolarHBondContact O-N 3.27Å; K49-L52 VanDerWaalsContact O-N 3.12Å; K49-V53 WeakPolarHBondContact O-CG2 3.48Å; K49-V53 PolarHBondContact O-N 3.49Å
50Q82.1Confident82.2Confident111 Ų11157.3 Ų57.352%0.51931%0.313SS..Hα-helixtrans-64.6-38.7177.4-176.157.943.400111.8E46 S47 E48 L52 S54E46-Q50 WeakPolarHBondContact O-CB 3.3Å; E46-Q50 PolarHBondContact O-N 2.69Å; S47-Q50 PolarHBondContact O-N 3.37Å; E48-Q50 VanDerWaalsContact C-N 3.34Å; E48-Q50 PolarHBondContact O-N 3.13Å; Q50-L52 VanDerWaalsContact C-N 3.34Å; Q50-S54 PolarHBondContact O-N 3.33Å; Q50-S54 VanDerWaalsContact O-N 3.14Å; Q50-S54 PolarHBondContact O-OG 3.49Å
51M77.4Confident82.1Confident55 Ų5556.9 Ų56.927%0.27131%0.309SS..Hα-helixtrans-64.4-41.2171.9-63.6-173.8-79.500110.7S47 E48 K49 V53 S54 E55 I165S47-M51 WeakPolarHBondContact O-CG 3.43Å; S47-M51 PolarHBondContact O-N 3.16Å; E48-M51 HydrophobicContact CB-CE 4.43Å; E48-M51 HydrophobicContact CG-CE 4.14Å; E48-M51 PolarHBondContact O-N 3.28Å; K49-M51 VanDerWaalsContact C-N 3.33Å; K49-M51 PolarHBondContact O-N 3.17Å; M51-V53 VanDerWaalsContact C-N 3.35Å; M51-V53 PolarHBondContact O-N 2.94Å; M51-S54 CarbonylContact O-C 3.57Å; M51-S54 WeakPolarHBondContact O-CA 3.33Å; M51-S54 VanDerWaalsContact O-CB 3.3Å; M51-S54 WeakPolarHBondContact O-CB 3.47Å; M51-S54 PolarHBondContact O-N 2.83Å; M51-E55 PolarHBondContact O-N 3.34Å; M51-I165 HydrophobicContact CB-CD1 3.84Å; M51-I165 HydrophobicContact CB-CG1 3.56Å; M51-I165 HydrophobicContact CB-CG2 4.36Å; M51-I165 HydrophobicContact CE-CG2 4.33Å; M51-I165 WeakPolarHBondContact O-CD1 3.32Å
52L81.3Confident82Confident11 Ų1155.4 Ų55.46%0.05830%0.304CS..Hα-helixtrans-60.2-43.7179.1-177.960.7000112.1L39 M44 E48 K49 Q50 S54 E55 V56 L82 L162 I165L39-L52 HydrophobicContact CD2-CD1 4.38Å; M44-L52 HydrophobicContact SD-CD2 4.04Å; E48-L52 WeakPolarHBondContact O-CB 3.34Å; E48-L52 PolarHBondContact O-N 3.49Å; K49-L52 WeakPolarHBondContact O-CB 3.12Å; K49-L52 PolarHBondContact O-N 3.27Å; K49-L52 VanDerWaalsContact O-N 3.12Å; Q50-L52 VanDerWaalsContact C-N 3.34Å; L52-S54 VanDerWaalsContact C-N 3.28Å; L52-S54 PolarHBondContact O-N 2.75Å; L52-E55 PolarHBondContact O-N 2.83Å; L52-V56 HydrophobicContact CD1-CG2 4.27Å; L52-V56 WeakPolarHBondContact O-CB 3.39Å; L52-V56 VanDerWaalsContact O-CG2 3.27Å; L52-V56 WeakPolarHBondContact O-CG2 3.47Å; L52-V56 PolarHBondContact O-N 3.05Å; L52-L82 HydrophobicContact CD1-CD2 4.17Å; L52-L82 HydrophobicContact CD2-CD2 3.62Å; L52-L82 HydrophobicContact CG-CD2 3.91Å; L52-L162 HydrophobicContact CD1-CD2 3.53Å; L52-I165 HydrophobicContact CB-CD1 3.84Å; L52-I165 HydrophobicContact CD1-CD1 4.17Å
53V83.2Confident82.1Confident64 Ų6460.2 Ų60.239%0.38831%0.314SS..Hα-helixtrans-58.7-42.8172.4171.80000111.1K49 M51 N57K49-V53 WeakPolarHBondContact O-CG2 3.48Å; K49-V53 PolarHBondContact O-N 3.49Å; M51-V53 VanDerWaalsContact C-N 3.35Å; M51-V53 PolarHBondContact O-N 2.94Å; V53-N57 WeakPolarHBondContact O-CB 3.33Å; V53-N57 PolarHBondContact O-N 3.24Å; V53-N57 PolarHBondContact O-ND2 3.46Å; V53-N57 VanDerWaalsContact O-ND2 3.09Å
54S79.1Confident82.5Confident55 Ų5555.3 Ų55.339%0.38528%0.282SS..Hα-helixtrans-65.1-44.4-179.6-54.50000111.9Q50 M51 L52 N57 L58Q50-S54 PolarHBondContact O-N 3.33Å; Q50-S54 VanDerWaalsContact O-N 3.14Å; Q50-S54 PolarHBondContact O-OG 3.49Å; M51-S54 CarbonylContact O-C 3.57Å; M51-S54 WeakPolarHBondContact O-CA 3.33Å; M51-S54 VanDerWaalsContact O-CB 3.3Å; M51-S54 WeakPolarHBondContact O-CB 3.47Å; M51-S54 PolarHBondContact O-N 2.83Å; L52-S54 VanDerWaalsContact C-N 3.28Å; L52-S54 PolarHBondContact O-N 2.75Å; S54-N57 PolarHBondContact O-N 3.36Å; S54-L58 PolarHBondContact O-N 2.99Å
55E78.6Confident82.9Confident8 Ų855.6 Ų55.64%0.03729%0.286CS..Hα-helixtrans-66.9-42.8177.1-65.3-66.3164.300112.3M51 L52 N57 L58 L59 G161 R164 I165M51-E55 PolarHBondContact O-N 3.34Å; L52-E55 PolarHBondContact O-N 2.83Å; E55-N57 VanDerWaalsContact C-N 3.27Å; E55-N57 PolarHBondContact O-N 2.91Å; E55-L58 WeakPolarHBondContact O-CB 3Å; E55-L58 PolarHBondContact O-N 3.19Å; E55-L58 VanDerWaalsContact O-N 3.13Å; E55-L59 WeakPolarHBondContact O-CG 3.41Å; E55-L59 PolarHBondContact O-N 3.02Å; E55-G161 WeakPolarHBondContact CB-O 3.23Å; E55-R164 WeakPolarHBondContact OE1-CB 3.23Å; E55-R164 WeakPolarHBondContact OE1-CD 3.49Å; E55-R164 IonicContact OE1-CZ 3.64Å; E55-R164 IonicContact OE1-NE 3.46Å; E55-R164 PolarHBondContact OE1-NE 3.18Å; E55-R164 IonicContact OE1-NH2 2.73Å; E55-I165 HydrophobicContact CB-CD1 4.04Å; E55-I165 HydrophobicContact CG-CD1 3.42Å; E55-I165 VanDerWaalsContact CG-CD1 3.42Å; E55-I165 HydrophobicContact CG-CG1 3.83Å
56V83.3Confident83.4Confident2 Ų253.4 Ų53.41%0.01227%0.268CS..Hα-helixtrans-62-37.5176.1171.20000111.2L52 L59 R60 Y70 L82 I84L52-V56 HydrophobicContact CD1-CG2 4.27Å; L52-V56 WeakPolarHBondContact O-CB 3.39Å; L52-V56 VanDerWaalsContact O-CG2 3.27Å; L52-V56 WeakPolarHBondContact O-CG2 3.47Å; L52-V56 PolarHBondContact O-N 3.05Å; V56-L59 PolarHBondContact O-N 3.16Å; V56-R60 WeakPolarHBondContact O-CB 3.42Å; V56-R60 PolarHBondContact O-N 3.49Å; V56-R60 VanDerWaalsContact O-N 3.1Å; V56-Y70 HydrophobicContact CG1-CE2 3.99Å; V56-L82 HydrophobicContact CG2-CD2 4.37Å; V56-I84 HydrophobicContact CG2-CD1 3.86Å; V56-I84 HydrophobicContact CG2-CG1 4.4Å
57N83.2Confident83.8Confident47 Ų4747 Ų4725%0.25124%0.238SC..Hα-helixtrans-66-39.5175.1-72.4-29.4000111.9V53 S54 E55 R60 E61V53-N57 WeakPolarHBondContact O-CB 3.33Å; V53-N57 PolarHBondContact O-N 3.24Å; V53-N57 PolarHBondContact O-ND2 3.46Å; V53-N57 VanDerWaalsContact O-ND2 3.09Å; S54-N57 PolarHBondContact O-N 3.36Å; E55-N57 VanDerWaalsContact C-N 3.27Å; E55-N57 PolarHBondContact O-N 2.91Å; N57-R60 PolarHBondContact O-N 3.11Å; N57-E61 WeakPolarHBondContact O-CG 3.25Å; N57-E61 PolarHBondContact O-N 2.97Å
58L80.2Confident84.4Confident29 Ų2944.1 Ų44.115%0.15222%0.216CC..Hα-helixtrans-64-47.4175-177.8159.9000111.1S54 E55 R60 E61 L62 V137S54-L58 PolarHBondContact O-N 2.99Å; E55-L58 WeakPolarHBondContact O-CB 3Å; E55-L58 PolarHBondContact O-N 3.19Å; E55-L58 VanDerWaalsContact O-N 3.13Å; L58-R60 PolarHBondContact O-N 3.32Å; L58-E61 WeakPolarHBondContact O-CB 3.4Å; L58-E61 PolarHBondContact O-N 3.32Å; L58-L62 HydrophobicContact CD2-CD1 3.67Å; L58-L62 HydrophobicContact CD2-CG 4.13Å; L58-L62 PolarHBondContact O-N 3.15Å; L58-V137 HydrophobicContact CD1-CG1 4.2Å; L58-V137 HydrophobicContact CD1-CG2 3.77Å; L58-V137 HydrophobicContact CD2-CG1 3.83Å; L58-V137 HydrophobicContact CD2-CG2 4.19Å; L58-V137 HydrophobicContact CG-CG2 4.14Å
59L82.8Confident85Confident23 Ų2345.8 Ų45.812%0.1222%0.221CC..Hα-helixtrans-54.5-40175.8-76.1178.8000112.6E55 V56 E61 L62 Y70 F160E55-L59 WeakPolarHBondContact O-CG 3.41Å; E55-L59 PolarHBondContact O-N 3.02Å; V56-L59 PolarHBondContact O-N 3.16Å; L59-E61 VanDerWaalsContact C-N 3.27Å; L59-E61 PolarHBondContact O-N 3.46Å; L59-L62 PolarHBondContact O-N 3.38Å; L59-Y70 HydrophobicContact CB-CD2 4.34Å; L59-F160 HydrophobicContact CD2-CB 3.35Å; L59-F160 HydrophobicContact CD2-CG 4.42Å
60R85.5Confident85.5Confident122 Ų12244.3 Ų44.346%0.4621%0.214SC..Hα-helixtrans-66.1-29.1178.1-176.6-177.765.8178.2-1.5113V56 N57 L58 Y70V56-R60 WeakPolarHBondContact O-CB 3.42Å; V56-R60 PolarHBondContact O-N 3.49Å; V56-R60 VanDerWaalsContact O-N 3.1Å; N57-R60 PolarHBondContact O-N 3.11Å; L58-R60 PolarHBondContact O-N 3.32Å; R60-Y70 HydrophobicContact CB-CD1 3.75Å; R60-Y70 HydrophobicContact CB-CE1 3.82Å; R60-Y70 HydrophobicContact CB-CG 4.3Å; R60-Y70 HydrophobicContact CG-CD1 3.8Å; R60-Y70 HydrophobicContact CG-CE1 3.72Å
61E83.7Confident86Confident70 Ų7042.4 Ų42.433%0.32720%0.202SC..Hα-helixtrans-79.8-31.4179.9-70175.7175.100112.5N57 L58 L59 K63 R130 R134N57-E61 WeakPolarHBondContact O-CG 3.25Å; N57-E61 PolarHBondContact O-N 2.97Å; L58-E61 WeakPolarHBondContact O-CB 3.4Å; L58-E61 PolarHBondContact O-N 3.32Å; L59-E61 VanDerWaalsContact C-N 3.27Å; L59-E61 PolarHBondContact O-N 3.46Å; E61-K63 PolarHBondContact O-N 2.97Å; E61-R130 IonicContact OE2-CZ 3.94Å; E61-R130 IonicContact OE2-NH1 2.68Å; E61-R130 PolarHBondContact OE2-NH1 3.41Å; E61-R130 IonicContact OE2-NH2 3.78Å; E61-R130 PolarHBondContact OE2-NH2 2.9Å; E61-R134 IonicContact OE1-CZ 2.79Å; E61-R134 IonicContact OE1-NH1 3.61Å; E61-R134 PolarHBondContact OE1-NH1 3.42Å; E61-R134 IonicContact OE1-NH2 2.72Å; E61-R134 IonicContact OE2-CZ 3.48Å; E61-R134 IonicContact OE2-NH1 3.61Å; E61-R134 PolarHBondContact OE2-NH1 3.12Å
62L84.3Confident86.7Confident10 Ų1041.6 Ų41.65%0.05220%0.199CC..  trans-67.8102179.3-67.1175.9000111.6L58 L59 I67 F160L58-L62 HydrophobicContact CD2-CD1 3.67Å; L58-L62 HydrophobicContact CD2-CG 4.13Å; L58-L62 PolarHBondContact O-N 3.15Å; L59-L62 PolarHBondContact O-N 3.38Å; L62-I67 HydrophobicContact CB-CD1 4.41Å; L62-I67 HydrophobicContact CB-CG2 4.33Å; L62-F160 HydrophobicContact CD1-CB 4.33Å; L62-F160 HydrophobicContact CD1-CD1 3.92Å; L62-F160 HydrophobicContact CD1-CD2 4.41Å; L62-F160 HydrophobicContact CD1-CE1 4.29Å; L62-F160 HydrophobicContact CD1-CG 3.97Å
63K87.3Confident87.2Confident139 Ų13945.5 Ų45.560%0.60421%0.213SC*.  trans-122.377.3-176.7-70.2177.6-175172.50111.6E61E61-K63 PolarHBondContact O-N 2.97Å
64H89.3Confident87.6Confident25 Ų2542.6 Ų42.612%0.11620%0.196CC..  trans-123.5147178.3-167.5-97.2000111.5N66 I67 E126H64-N66 PolarHBondContact CE1-OD1 3.25Å; H64-N66 PolarHBondContact ND1-N 2.86Å; H64-N66 VanDerWaalsContact ND1-N 3.12Å; H64-N66 PolarHBondContact O-N 3.43Å; H64-I67 HydrophobicContact CB-CB 4.01Å; H64-I67 HydrophobicContact CB-CD1 3.74Å; H64-I67 HydrophobicContact CB-CG1 3.83Å; H64-I67 PolarHBondContact O-N 2.86Å; H64-I67 VanDerWaalsContact O-O 3.14Å; H64-E126 HydrophobicContact CB-CB 4.38Å; H64-E126 HydrophobicContact CB-CG 4.07Å
65P91.7Very high88.2Confident31 Ų3144.1 Ų44.120%0.20120%0.199CC..THydrogen-bonded Turntrans-59.1-33.2176.222-35.1000113.8K156 V282P65-K156 PolarHBondContact O-NZ 3.17Å; P65-V282 HydrophobicContact CG-CG2 3.74Å
66N93.6Very high88.8Confident3 Ų345.1 Ų45.12%0.01620%0.204CC..THydrogen-bonded Turntrans-96.518.9179.4-50103.2000113.2H64 Q119 A123 V155 K156 L157H64-N66 PolarHBondContact CE1-OD1 3.25Å; H64-N66 PolarHBondContact ND1-N 2.86Å; H64-N66 VanDerWaalsContact ND1-N 3.12Å; H64-N66 PolarHBondContact O-N 3.43Å; N66-Q119 HydrophobicContact CB-CB 4.33Å; N66-Q119 WeakPolarHBondContact CB-O 3.23Å; N66-Q119 WeakPolarHBondContact ND2-CB 3.26Å; N66-Q119 WeakPolarHBondContact ND2-CG 3.4Å; N66-Q119 PolarHBondContact ND2-OE1 2.97Å; N66-Q119 VanDerWaalsContact ND2-OE1 3.16Å; N66-A123 HydrophobicContact CB-CB 4.07Å; N66-A123 WeakPolarHBondContact O-CB 3.44Å; N66-V155 WeakPolarHBondContact CA-O 3.42Å; N66-V155 WeakPolarHBondContact CB-O 3.45Å; N66-V155 PolarHBondContact ND2-O 3.27Å; N66-V155 VanDerWaalsContact ND2-O 3.13Å; N66-K156 WeakPolarHBondContact O-CA 3.45Å; N66-L157 WeakPolarHBondContact O-CB 3.34Å; N66-L157 PolarHBondContact O-N 3.24Å
67I92.3Very high89.1Confident2 Ų255 Ų551%0.0124%0.241CC..BIsolated β-bridgetrans-119.6134.9169.7-68.6178.1000107.4L62 H64 R69 A123 E126 L157 F160L62-I67 HydrophobicContact CB-CD1 4.41Å; L62-I67 HydrophobicContact CB-CG2 4.33Å; H64-I67 HydrophobicContact CB-CB 4.01Å; H64-I67 HydrophobicContact CB-CD1 3.74Å; H64-I67 HydrophobicContact CB-CG1 3.83Å; H64-I67 PolarHBondContact O-N 2.86Å; H64-I67 VanDerWaalsContact O-O 3.14Å; I67-R69 PolarHBondContact O-N 2.96Å; I67-A123 HydrophobicContact CG1-CB 3.95Å; I67-E126 HydrophobicContact CD1-CB 4.3Å; I67-E126 HydrophobicContact CD1-CG 4.22Å; I67-L157 CarbonylContact C-O 3.48Å; I67-L157 WeakPolarHBondContact CA-O 3.37Å; I67-F160 HydrophobicContact CB-CE2 3.99Å; I67-F160 HydrophobicContact CB-CZ 4.45Å; I67-F160 HydrophobicContact CD1-CE1 4.48Å; I67-F160 HydrophobicContact CD1-CE2 3.99Å; I67-F160 HydrophobicContact CD1-CZ 3.62Å; I67-F160 HydrophobicContact CG1-CE2 3.68Å; I67-F160 HydrophobicContact CG1-CZ 3.65Å; I67-F160 HydrophobicContact CG2-CD2 3.92Å; I67-F160 HydrophobicContact CG2-CE2 3.39Å; I67-F160 HydrophobicContact CG2-CZ 4.16Å
68V92.5Very high89.4Confident19 Ų1958.9 Ų58.912%0.11527%0.267CS..PPolyproline II helixtrans-56.7120.5174.7174.10000108.6Y70 M86 E87 F148 K156 L157V68-Y70 PolarHBondContact O-N 3.49Å; V68-M86 HydrophobicContact CG1-CB 4.09Å; V68-E87 HydrophobicContact CG1-CB 4.08Å; V68-F148 HydrophobicContact CG2-CD2 3.7Å; V68-F148 HydrophobicContact CG2-CE2 4.37Å; V68-F148 HydrophobicContact CG2-CG 4.47Å; V68-K156 HydrophobicContact CG2-CB 3.8Å; V68-L157 WeakPolarHBondContact CG2-O 3.28Å; V68-L157 PolarHBondContact N-O 3.3Å
69R91.8Very high89.9Confident76 Ų7662.2 Ų62.229%0.28728%0.284SS..PPolyproline II helixtrans-71.4125.4-174176.660.46291.51.8111.4I67 Y71 M86 E87I67-R69 PolarHBondContact O-N 2.96Å; R69-Y71 HydrophobicContact CB-CD2 4.45Å; R69-Y71 HydrophobicContact CB-CE2 3.92Å; R69-Y71 HydrophobicContact CG-CD2 4.02Å; R69-Y71 HydrophobicContact CG-CE2 3.65Å; R69-Y71 WeakPolarHBondContact O-CD2 3.41Å; R69-M86 CarbonylContact O-C 3.56Å; R69-M86 WeakPolarHBondContact O-CA 3.46Å; R69-E87 HydrophobicContact CB-CB 4.03Å; R69-E87 PolarHBondContact N-OE2 3.36Å; R69-E87 VanDerWaalsContact N-OE2 3.07Å; R69-E87 PolarHBondContact O-N 2.9Å
70Y92Very high90.2Very high28 Ų2863.6 Ų63.611%0.1129%0.294CS..EExtended strand (participates in β ladder)trans-68.7133.9160.8174.9-84.9000110.6V56 L59 R60 V68 D72 R73 I84V56-Y70 HydrophobicContact CG1-CE2 3.99Å; L59-Y70 HydrophobicContact CB-CD2 4.34Å; R60-Y70 HydrophobicContact CB-CD1 3.75Å; R60-Y70 HydrophobicContact CB-CE1 3.82Å; R60-Y70 HydrophobicContact CB-CG 4.3Å; R60-Y70 HydrophobicContact CG-CD1 3.8Å; R60-Y70 HydrophobicContact CG-CE1 3.72Å; V68-Y70 PolarHBondContact O-N 3.49Å; Y70-D72 WeakPolarHBondContact CE2-O 3.32Å; Y70-D72 VanDerWaalsContact CZ-C 3.42Å; Y70-D72 PolarHBondContact OH-O 2.82Å; Y70-R73 WeakPolarHBondContact OH-CB 3.44Å; Y70-R73 PolarHBondContact OH-N 3.19Å; Y70-R73 VanDerWaalsContact OH-N 3.16Å; Y70-I84 HydrophobicContact CD2-CG2 3.99Å; Y70-I84 HydrophobicContact CE2-CG2 3.98Å
71Y92.4Very high90.5Very high71 Ų7158.7 Ų58.728%0.27828%0.278SS..EExtended strand (participates in β ladder)trans-109.8-51.5175.2-81.9-95.7000112K32 L34 R69 V85 E87K32-Y71 HydrophobicContact CD-CE1 4.44Å; K32-Y71 VanDerWaalsContact CE-OH 3.3Å; K32-Y71 WeakPolarHBondContact CE-OH 3.24Å; K32-Y71 PolarHBondContact NZ-OH 2.95Å; L34-Y71 HydrophobicContact CD2-CD1 4.25Å; L34-Y71 HydrophobicContact CD2-CD2 3.72Å; L34-Y71 HydrophobicContact CD2-CE1 4.24Å; L34-Y71 HydrophobicContact CD2-CE2 3.7Å; L34-Y71 HydrophobicContact CD2-CG 4Å; R69-Y71 HydrophobicContact CB-CD2 4.45Å; R69-Y71 HydrophobicContact CB-CE2 3.92Å; R69-Y71 HydrophobicContact CG-CD2 4.02Å; R69-Y71 HydrophobicContact CG-CE2 3.65Å; R69-Y71 WeakPolarHBondContact O-CD2 3.41Å; Y71-V85 PolarHBondContact N-O 3.01Å; Y71-E87 HydrophobicContact CE2-CB 3.99Å
72D92.3Very high90.8Very high38 Ų3856 Ų5620%0.20327%0.266CS..EExtended strand (participates in β ladder)trans-160.6169.3-168.1-150.2-6.5000113.5S3 Y8 Y70 V85S3-D72 WeakPolarHBondContact CB-OD2 3.38Å; S3-D72 PolarHBondContact OG-OD2 3.16Å; Y8-D72 PolarHBondContact OH-OD2 3.18Å; Y70-D72 WeakPolarHBondContact CE2-O 3.32Å; Y70-D72 VanDerWaalsContact CZ-C 3.42Å; Y70-D72 PolarHBondContact OH-O 2.82Å; D72-V85 HydrophobicContact CB-CB 3.92Å; D72-V85 HydrophobicContact CB-CG2 4.06Å; D72-V85 PolarHBondContact N-O 3.49Å; D72-V85 PolarHBondContact O-N 3.19Å
73R91.8Very high91.1Very high94 Ų9456.5 Ų56.536%0.35527%0.267SS..EExtended strand (participates in β ladder)trans-132.3139.3168.270.7-176.2-173.2-157.20.8110.7Y70 L82 Y83Y70-R73 WeakPolarHBondContact OH-CB 3.44Å; Y70-R73 PolarHBondContact OH-N 3.19Å; Y70-R73 VanDerWaalsContact OH-N 3.16Å; R73-L82 HydrophobicContact CB-CD1 4.23Å; R73-Y83 CarbonylContact C-O 3.57Å; R73-Y83 VanDerWaalsContact CA-O 3.27Å; R73-Y83 WeakPolarHBondContact CA-O 3.34Å
74I93.1Very high91.3Very high3 Ų350 Ų502%0.01524%0.239CC..EExtended strand (participates in β ladder)trans-124.9132178.1-50.2164000107.6V5 Y8 W36 Y83 V85V5-I74 HydrophobicContact CG2-CG2 3.7Å; Y8-I74 HydrophobicContact CD2-CD1 3.6Å; Y8-I74 HydrophobicContact CE2-CD1 3.47Å; Y8-I74 VanDerWaalsContact CE2-CD1 3.47Å; Y8-I74 HydrophobicContact CE2-CG1 4.4Å; W36-I74 HydrophobicContact CE3-CD1 4.01Å; W36-I74 HydrophobicContact CZ3-CD1 3.93Å; I74-Y83 HydrophobicContact CB-CD2 4.27Å; I74-Y83 HydrophobicContact CG2-CD2 4.46Å; I74-Y83 PolarHBondContact N-O 3.29Å; I74-Y83 PolarHBondContact O-N 2.82Å; I74-V85 HydrophobicContact CD1-CG2 4Å; I74-V85 HydrophobicContact CG1-CG2 4.37Å
75I91.6Very high91.6Very high87 Ų8748.9 Ų48.945%0.44623%0.233SC..EExtended strand (participates in β ladder)trans-113.6110.2179.6-58174.6000107.7Y41 R77 L82Y41-I75 HydrophobicContact CE1-CG2 3.99Å; Y41-I75 WeakPolarHBondContact OH-CG2 3.47Å; I75-R77 HydrophobicContact CG2-CG 3.98Å; I75-L82 HydrophobicContact CG1-CD1 3.81Å
76D91.1Very high91.6Very high28 Ų2849.1 Ų49.115%0.1523%0.232CC..EExtended strand (participates in β ladder)trans-92.599.5168.8-178.6-6.4000108.8V5 T78 N79 T80 T81 Y83V5-D76 HydrophobicContact CG2-CB 4.37Å; D76-T78 VanDerWaalsContact C-N 3.29Å; D76-T78 PolarHBondContact O-N 2.94Å; D76-T78 WeakPolarHBondContact OD1-CB 3.43Å; D76-T78 PolarHBondContact OD1-N 3.16Å; D76-N79 PolarHBondContact OD1-N 3Å; D76-N79 PolarHBondContact OD2-ND2 3.46Å; D76-T80 WeakPolarHBondContact O-CA 3.49Å; D76-T80 PolarHBondContact O-N 2.85Å; D76-T80 VanDerWaalsContact O-N 3.09Å; D76-T81 PolarHBondContact N-O 2.73Å; D76-T81 PolarHBondContact O-N 3.31Å; D76-Y83 HydrophobicContact CB-CE2 3.92Å
77R89.3Confident91.6Very high210 Ų21051 Ų5179%0.79224%0.241SC*.THydrogen-bonded Turntrans-70.5-26.3-178.7-65.5-176.1-179.6178.4-0.5113.1Y41 I75Y41-R77 WeakPolarHBondContact OH-CA 3.25Å; I75-R77 HydrophobicContact CG2-CG 3.98Å
78T89.8Confident91.7Very high128 Ų12853.2 Ų53.279%0.78525%0.25SC*.THydrogen-bonded Turntrans-69-43.2-178.6-50.90000110.1D76D76-T78 VanDerWaalsContact C-N 3.29Å; D76-T78 PolarHBondContact O-N 2.94Å; D76-T78 WeakPolarHBondContact OD1-CB 3.43Å; D76-T78 PolarHBondContact OD1-N 3.16Å
79N89.1Confident91.8Very high99 Ų9953 Ų5353%0.52925%0.249SC..THydrogen-bonded Turntrans-10012.8-179.5-62.2-48000113.3D76 T81D76-N79 PolarHBondContact OD1-N 3Å; D76-N79 PolarHBondContact OD2-ND2 3.46Å; N79-T81 PolarHBondContact O-N 2.99Å; N79-T81 PolarHBondContact O-OG1 3.37Å
80T91.1Very high91.7Very high52 Ų5254.9 Ų54.932%0.31926%0.261SS..THydrogen-bonded Turntrans45.137.2-175.358.90000114.2D40 Y41 D76D40-T80 VanDerWaalsContact OD1-O 3.09Å; D40-T80 PolarHBondContact OD1-OG1 2.86Å; Y41-T80 VanDerWaalsContact CD1-C 3.49Å; Y41-T80 WeakPolarHBondContact CD1-O 3.23Å; Y41-T80 VanDerWaalsContact CE1-O 3.29Å; Y41-T80 WeakPolarHBondContact CE1-O 3.37Å; Y41-T80 HydrophobicContact CE2-CG2 4.41Å; Y41-T80 PolarHBondContact N-O 3.2Å; D76-T80 WeakPolarHBondContact O-CA 3.49Å; D76-T80 PolarHBondContact O-N 2.85Å; D76-T80 VanDerWaalsContact O-N 3.09Å
81T90.3Very high91.7Very high20 Ų2055.5 Ų55.512%0.12328%0.275CS..EExtended strand (participates in β ladder)trans-112.7129.6-172-59.70000111.3E38 L39 D76 N79 Y83E38-T81 HydrophobicContact CB-CG2 4.31Å; L39-T81 CarbonylContact O-C 3.59Å; L39-T81 WeakPolarHBondContact O-CA 3.29Å; D76-T81 PolarHBondContact N-O 2.73Å; D76-T81 PolarHBondContact O-N 3.31Å; N79-T81 PolarHBondContact O-N 2.99Å; N79-T81 PolarHBondContact O-OG1 3.37Å; T81-Y83 HydrophobicContact CG2-CD1 4.5Å; T81-Y83 HydrophobicContact CG2-CD2 4.05Å; T81-Y83 HydrophobicContact CG2-CE1 4.07Å; T81-Y83 HydrophobicContact CG2-CE2 3.55Å; T81-Y83 HydrophobicContact CG2-CG 4.49Å
82L89.9Confident91.7Very high13 Ų1353.5 Ų53.57%0.06828%0.277CS..EExtended strand (participates in β ladder)trans-99.7125.2168.4174.371.2000108.9E38 L39 Y41 L52 V56 R73 I75 I84E38-L82 CarbonylContact C-O 3.54Å; L39-L82 HydrophobicContact CB-CB 4.35Å; L39-L82 PolarHBondContact N-O 2.88Å; L39-L82 PolarHBondContact O-N 3.15Å; Y41-L82 HydrophobicContact CD1-CB 4.01Å; Y41-L82 HydrophobicContact CE1-CB 4.49Å; L52-L82 HydrophobicContact CD1-CD2 4.17Å; L52-L82 HydrophobicContact CD2-CD2 3.62Å; L52-L82 HydrophobicContact CG-CD2 3.91Å; V56-L82 HydrophobicContact CG2-CD2 4.37Å; R73-L82 HydrophobicContact CB-CD1 4.23Å; I75-L82 HydrophobicContact CG1-CD1 3.81Å; L82-I84 HydrophobicContact CD2-CD1 4.32Å; L82-I84 HydrophobicContact CD2-CG1 4.17Å; L82-I84 HydrophobicContact CG-CG1 4.23Å
83Y91.9Very high91.7Very high21 Ų2153.3 Ų53.38%0.08228%0.276CS..EExtended strand (participates in β ladder)trans-102.8124.8170.4-55.9-97.3000109.2V5 W36 K37 E38 R73 I74 D76 T81V5-Y83 HydrophobicContact CG2-CD2 4.31Å; V5-Y83 HydrophobicContact CG2-CE2 3.95Å; W36-Y83 AromaticContact CD2-CD1 3.5Å; W36-Y83 HydrophobicContact CD2-CD1 3.5Å; W36-Y83 VanDerWaalsContact CD2-CD1 3.5Å; W36-Y83 HydrophobicContact CD2-CE1 4.2Å; W36-Y83 HydrophobicContact CD2-CG 4.19Å; W36-Y83 AromaticContact CE2-CD1 3.58Å; W36-Y83 AromaticContact CE2-CE1 3.8Å; W36-Y83 AromaticContact CE3-CD1 3.81Å; W36-Y83 HydrophobicContact CE3-CD1 3.81Å; W36-Y83 HydrophobicContact CE3-CG 4.1Å; W36-Y83 AromaticContact CG-CD1 3.87Å; W36-Y83 HydrophobicContact CG-CD1 3.87Å; W36-Y83 HydrophobicContact CH2-CD1 4.31Å; W36-Y83 HydrophobicContact CH2-CE1 4.29Å; W36-Y83 AromaticContact CZ2-CD1 3.97Å; W36-Y83 HydrophobicContact CZ2-CD1 3.97Å; W36-Y83 AromaticContact CZ2-CE1 3.83Å; W36-Y83 HydrophobicContact CZ2-CE1 3.83Å; W36-Y83 HydrophobicContact CZ3-CD1 4.22Å; W36-Y83 HydrophobicContact CZ3-CG 4.48Å; W36-Y83 AromaticContact NE1-CD1 3.93Å; K37-Y83 WeakPolarHBondContact O-CA 3.49Å; E38-Y83 HydrophobicContact CB-CE1 4.49Å; E38-Y83 HydrophobicContact CG-CD1 3.72Å; E38-Y83 HydrophobicContact CG-CE1 3.54Å; R73-Y83 CarbonylContact C-O 3.57Å; R73-Y83 VanDerWaalsContact CA-O 3.27Å; R73-Y83 WeakPolarHBondContact CA-O 3.34Å; I74-Y83 HydrophobicContact CB-CD2 4.27Å; I74-Y83 HydrophobicContact CG2-CD2 4.46Å; I74-Y83 PolarHBondContact N-O 3.29Å; I74-Y83 PolarHBondContact O-N 2.82Å; D76-Y83 HydrophobicContact CB-CE2 3.92Å; T81-Y83 HydrophobicContact CG2-CD1 4.5Å; T81-Y83 HydrophobicContact CG2-CD2 4.05Å; T81-Y83 HydrophobicContact CG2-CE1 4.07Å; T81-Y83 HydrophobicContact CG2-CE2 3.55Å; T81-Y83 HydrophobicContact CG2-CG 4.49Å
84I91.6Very high91.9Very high3 Ų348.8 Ų48.82%0.01526%0.259CS..EExtended strand (participates in β ladder)trans-103.4110.5173.1-58.4176.5000108W36 K37 L39 V56 Y70 L82 M86 L162W36-I84 CarbonylContact C-O 3.52Å; W36-I84 VanDerWaalsContact CA-O 3.23Å; W36-I84 WeakPolarHBondContact CA-O 3.44Å; K37-I84 PolarHBondContact N-O 3.44Å; K37-I84 PolarHBondContact O-N 2.84Å; L39-I84 HydrophobicContact CD1-CD1 3.66Å; L39-I84 HydrophobicContact CD1-CG1 3.95Å; V56-I84 HydrophobicContact CG2-CD1 3.86Å; V56-I84 HydrophobicContact CG2-CG1 4.4Å; Y70-I84 HydrophobicContact CD2-CG2 3.99Å; Y70-I84 HydrophobicContact CE2-CG2 3.98Å; L82-I84 HydrophobicContact CD2-CD1 4.32Å; L82-I84 HydrophobicContact CD2-CG1 4.17Å; L82-I84 HydrophobicContact CG-CG1 4.23Å; I84-M86 HydrophobicContact CG2-CG 3.99Å; I84-M86 HydrophobicContact CG2-SD 4.29Å; I84-L162 HydrophobicContact CD1-CD2 4.2Å
85V93.7Very high92Very high0 Ų050.2 Ų50.20%027%0.27CS..EExtended strand (participates in β ladder)trans-86.9125.6-177.8-172.70000110.1Y8 I25 L34 V35 W36 Y71 D72 I74Y8-V85 HydrophobicContact CE1-CG1 4.19Å; I25-V85 HydrophobicContact CD1-CG1 4.08Å; I25-V85 HydrophobicContact CD1-CG2 4.45Å; L34-V85 HydrophobicContact CB-CG1 4.1Å; L34-V85 HydrophobicContact CD1-CG1 3.75Å; L34-V85 HydrophobicContact CG-CG1 4.44Å; V35-V85 CarbonylContact O-C 3.59Å; V35-V85 WeakPolarHBondContact O-CA 3.48Å; W36-V85 HydrophobicContact CB-CG2 4.32Å; Y71-V85 PolarHBondContact N-O 3.01Å; D72-V85 HydrophobicContact CB-CB 3.92Å; D72-V85 HydrophobicContact CB-CG2 4.06Å; D72-V85 PolarHBondContact N-O 3.49Å; D72-V85 PolarHBondContact O-N 3.19Å; I74-V85 HydrophobicContact CD1-CG2 4Å; I74-V85 HydrophobicContact CG1-CG2 4.37Å
86M93.4Very high92.1Very high36 Ų3649.2 Ų49.218%0.17727%0.272CS..EExtended strand (participates in β ladder)trans-135165.2-173.2-57.4-177.3-67.300111.9V35 K37 V68 R69 I84 Y88V35-M86 HydrophobicContact CG2-CB 3.88Å; V35-M86 HydrophobicContact CG2-CE 4.27Å; V35-M86 PolarHBondContact N-O 2.85Å; V35-M86 PolarHBondContact O-N 3.46Å; K37-M86 HydrophobicContact CB-CE 4.01Å; K37-M86 HydrophobicContact CD-CE 4.5Å; V68-M86 HydrophobicContact CG1-CB 4.09Å; R69-M86 CarbonylContact O-C 3.56Å; R69-M86 WeakPolarHBondContact O-CA 3.46Å; I84-M86 HydrophobicContact CG2-CG 3.99Å; I84-M86 HydrophobicContact CG2-SD 4.29Å; M86-Y88 PolarHBondContact O-N 2.81Å
87E93.4Very high92.4Very high43 Ų4348.5 Ų48.520%0.20127%0.267CS..EExtended strand (participates in β ladder)trans-58.6130.7172.6-172.8173.9-161.400111.9V68 R69 Y71 K156V68-E87 HydrophobicContact CG1-CB 4.08Å; R69-E87 HydrophobicContact CB-CB 4.03Å; R69-E87 PolarHBondContact N-OE2 3.36Å; R69-E87 VanDerWaalsContact N-OE2 3.07Å; R69-E87 PolarHBondContact O-N 2.9Å; Y71-E87 HydrophobicContact CE2-CB 3.99Å; E87-K156 VanDerWaalsContact CD-CE 3.44Å; E87-K156 WeakPolarHBondContact OE1-CE 3.25Å; E87-K156 IonicContact OE1-NZ 2.75Å; E87-K156 PolarHBondContact OE1-NZ 2.71Å; E87-K156 WeakPolarHBondContact OE2-CE 3.43Å; E87-K156 IonicContact OE2-NZ 3.49Å; E87-K156 PolarHBondContact OE2-NZ 3.41Å
88Y93.8Very high92.7Very high49 Ų4938.7 Ų38.719%0.19223%0.231CC..  trans-80.5128.2167.9179-123.3000110.5I14 K24 I33 V35 M86 E90I14-Y88 HydrophobicContact CD1-CD2 4.27Å; I14-Y88 HydrophobicContact CD1-CE2 4.05Å; K24-Y88 HydrophobicContact CD-CE1 4.19Å; K24-Y88 HydrophobicContact CD-CE2 4.21Å; K24-Y88 HydrophobicContact CG-CE2 4.49Å; K24-Y88 PolarHBondContact NZ-OH 3.05Å; K24-Y88 VanDerWaalsContact NZ-OH 3.17Å; I33-Y88 HydrophobicContact CG2-CD1 3.48Å; I33-Y88 VanDerWaalsContact CG2-CD1 3.48Å; I33-Y88 HydrophobicContact CG2-CE1 4.12Å; I33-Y88 HydrophobicContact CG2-CG 3.98Å; V35-Y88 HydrophobicContact CG1-CD2 3.47Å; V35-Y88 VanDerWaalsContact CG1-CD2 3.47Å; V35-Y88 HydrophobicContact CG1-CE2 4.41Å; V35-Y88 HydrophobicContact CG1-CG 4.13Å; M86-Y88 PolarHBondContact O-N 2.81Å; Y88-E90 HydrophobicContact CD1-CG 3.76Å; Y88-E90 HydrophobicContact CE1-CB 4.18Å; Y88-E90 HydrophobicContact CE1-CG 3.65Å
89C93.8Very high93.1Very high14 Ų1436 Ų3610%0.09522%0.218CC..  trans-106.3103.9177.7-62.70000109.6G91 G92 F148 L149 K156C89-G91 VanDerWaalsContact C-N 3.28Å; C89-G91 PolarHBondContact O-N 2.91Å; C89-G92 PolarHBondContact O-N 3Å; C89-F148 HydrophobicContact CB-CB 3.49Å; C89-F148 VanDerWaalsContact CB-CB 3.49Å; C89-F148 HydrophobicContact CB-CD1 4.48Å; C89-F148 HydrophobicContact CB-CG 4.21Å; C89-L149 CarbonylContact C-O 3.53Å; C89-L149 WeakPolarHBondContact CB-O 3.43Å; C89-K156 VanDerWaalsContact SG-CD 3.58Å
90E91.1Very high93.4Very high116 Ų11637.2 Ų37.254%0.54221%0.214SC..THydrogen-bonded Turntrans-69.6-23.4-169.1-49.1-164.1155.500113.9Y88 G92 I151Y88-E90 HydrophobicContact CD1-CG 3.76Å; Y88-E90 HydrophobicContact CE1-CB 4.18Å; Y88-E90 HydrophobicContact CE1-CG 3.65Å; E90-G92 PolarHBondContact O-N 3.23Å; E90-I151 HydrophobicContact CB-CG2 3.73Å; E90-I151 HydrophobicContact CG-CG2 3.88Å; E90-I151 WeakPolarHBondContact OE2-CG2 3.44Å
91G90.8Very high93.7Very high40 Ų4034.7 Ų34.741%0.41220%0.199SC..THydrogen-bonded Turntrans-78.11-179.400000114.5C89 L149C89-G91 VanDerWaalsContact C-N 3.28Å; C89-G91 PolarHBondContact O-N 2.91Å; G91-L149 VanDerWaalsContact CA-O 3.23Å; G91-L149 WeakPolarHBondContact CA-O 3.28Å; G91-L149 PolarHBondContact N-O 3.17Å
92G92.4Very high94.1Very high30 Ų3038 Ų3831%0.30922%0.215SC..  trans72.8-154.3-176.800000112.4C89 E90 F148 L149C89-G92 PolarHBondContact O-N 3Å; E90-G92 PolarHBondContact O-N 3.23Å; G92-F148 CarbonylContact O-C 3.55Å; G92-F148 VanDerWaalsContact O-CA 3.29Å; G92-F148 WeakPolarHBondContact O-CA 3.43Å; G92-L149 PolarHBondContact O-N 3.1Å
93D93.5Very high94.5Very high33 Ų3346.3 Ų46.318%0.17625%0.251CS..BIsolated β-bridgetrans-114.2162.9-177.668.591.7000112.9A95 S96 L97 I147 F148D93-A95 VanDerWaalsContact C-N 3.31Å; D93-A95 PolarHBondContact O-N 3.47Å; D93-A95 VanDerWaalsContact OD1-CA 3.28Å; D93-A95 WeakPolarHBondContact OD1-CA 3.48Å; D93-A95 WeakPolarHBondContact OD1-CB 3.1Å; D93-A95 PolarHBondContact OD1-N 3.32Å; D93-S96 PolarHBondContact O-N 3.13Å; D93-S96 PolarHBondContact OD1-N 2.91Å; D93-S96 WeakPolarHBondContact OD2-CB 3.48Å; D93-S96 PolarHBondContact OD2-OG 2.99Å; D93-L97 PolarHBondContact O-N 3.36Å; D93-L97 VanDerWaalsContact O-N 3.13Å; D93-I147 CarbonylContact C-O 3.59Å; D93-I147 VanDerWaalsContact CA-O 3.25Å; D93-I147 WeakPolarHBondContact CA-O 3.45Å; D93-F148 HydrophobicContact CB-CD1 4.13Å; D93-F148 HydrophobicContact CB-CE1 4.25Å
94L95.7Very high94.7Very high0 Ų050 Ų500%027%0.269CS..Hα-helixtrans-68.3-25.5-179.9-69-174.3000113.4L97 I98 F112 V116 P144 I147 L149 L205 L209L94-L97 HydrophobicContact CD2-CD2 3.78Å; L94-L97 WeakPolarHBondContact O-CB 3.28Å; L94-L97 PolarHBondContact O-N 2.9Å; L94-I98 WeakPolarHBondContact O-CD1 3.23Å; L94-I98 VanDerWaalsContact O-CG1 3.28Å; L94-I98 WeakPolarHBondContact O-CG1 3.4Å; L94-I98 PolarHBondContact O-N 3.41Å; L94-F112 HydrophobicContact CD2-CZ 4.36Å; L94-V116 HydrophobicContact CD1-CG1 4.1Å; L94-P144 HydrophobicContact CB-CB 3.88Å; L94-P144 PolarHBondContact N-O 3.27Å; L94-P144 VanDerWaalsContact N-O 3.17Å; L94-I147 HydrophobicContact CB-CB 4.34Å; L94-I147 HydrophobicContact CD1-CB 3.61Å; L94-I147 HydrophobicContact CD1-CG1 4.16Å; L94-I147 HydrophobicContact CD1-CG2 3.43Å; L94-I147 VanDerWaalsContact CD1-CG2 3.43Å; L94-I147 HydrophobicContact CG-CB 3.81Å; L94-I147 HydrophobicContact CG-CG2 3.77Å; L94-I147 PolarHBondContact N-O 3.23Å; L94-L149 HydrophobicContact CD2-CD1 4.02Å; L94-L149 HydrophobicContact CD2-CD2 4.01Å; L94-L149 HydrophobicContact CD2-CG 4.08Å; L94-L205 HydrophobicContact CD1-CD2 4.16Å; L94-L209 HydrophobicContact CD1-CD1 4.22Å; L94-L209 HydrophobicContact CD1-CD2 4.31Å; L94-L209 HydrophobicContact CD2-CD2 4.47Å
95A94.5Very high95Very high32 Ų3260.9 Ų60.926%0.26431%0.31SS..Hα-helixtrans-66.7-43175.800000110.6D93 L97 I98 S99 P144 A145D93-A95 VanDerWaalsContact C-N 3.31Å; D93-A95 PolarHBondContact O-N 3.47Å; D93-A95 VanDerWaalsContact OD1-CA 3.28Å; D93-A95 WeakPolarHBondContact OD1-CA 3.48Å; D93-A95 WeakPolarHBondContact OD1-CB 3.1Å; D93-A95 PolarHBondContact OD1-N 3.32Å; A95-L97 VanDerWaalsContact C-N 3.31Å; A95-L97 PolarHBondContact O-N 2.86Å; A95-I98 PolarHBondContact O-N 3.47Å; A95-S99 WeakPolarHBondContact O-CB 3.31Å; A95-S99 PolarHBondContact O-N 2.49Å; A95-S99 PolarHBondContact O-OG 2.81Å; A95-P144 HydrophobicContact CB-CB 3.89Å; A95-P144 PolarHBondContact N-O 3.49Å; A95-A145 HydrophobicContact CB-CB 4.2Å
96S94.8Very high95.1Very high67 Ų6766.1 Ų66.147%0.46933%0.329SS..Hα-helixtrans-60.1-40.2171.7-65.10000111.9D93 S99 R100D93-S96 PolarHBondContact O-N 3.13Å; D93-S96 PolarHBondContact OD1-N 2.91Å; D93-S96 WeakPolarHBondContact OD2-CB 3.48Å; D93-S96 PolarHBondContact OD2-OG 2.99Å; S96-S99 PolarHBondContact O-N 3.4Å; S96-R100 WeakPolarHBondContact O-CB 3.24Å; S96-R100 PolarHBondContact O-N 3.46Å
97L95.9Very high95.4Very high12 Ų1269 Ų696%0.06334%0.339CS..Hα-helixtrans-62.1-48.3174.7176.864.9000112.2D93 L94 A95 S99 R100 C101 L108 F112 L149D93-L97 PolarHBondContact O-N 3.36Å; D93-L97 VanDerWaalsContact O-N 3.13Å; L94-L97 HydrophobicContact CD2-CD2 3.78Å; L94-L97 WeakPolarHBondContact O-CB 3.28Å; L94-L97 PolarHBondContact O-N 2.9Å; A95-L97 VanDerWaalsContact C-N 3.31Å; A95-L97 PolarHBondContact O-N 2.86Å; L97-S99 VanDerWaalsContact C-N 3.34Å; L97-S99 PolarHBondContact O-N 2.97Å; L97-R100 PolarHBondContact O-N 2.9Å; L97-C101 PolarHBondContact O-N 3.46Å; L97-C101 PolarHBondContact O-SG 3.25Å; L97-L108 HydrophobicContact CD1-CD2 4.21Å; L97-L108 HydrophobicContact CD2-CD1 4.15Å; L97-L108 HydrophobicContact CD2-CD2 4Å; L97-L108 HydrophobicContact CG-CD2 4.19Å; L97-F112 HydrophobicContact CD2-CE1 3.57Å; L97-F112 HydrophobicContact CD2-CZ 3.67Å; L97-L149 HydrophobicContact CD2-CD1 4.21Å
98I97Very high95.6Very high4 Ų467.4 Ų67.42%0.02133%0.332CS..Hα-helixtrans-59.7-46.7178.5-70.1158.8000109.9L94 A95 R100 C101 I102 P144 E208 L209 L212L94-I98 WeakPolarHBondContact O-CD1 3.23Å; L94-I98 VanDerWaalsContact O-CG1 3.28Å; L94-I98 WeakPolarHBondContact O-CG1 3.4Å; L94-I98 PolarHBondContact O-N 3.41Å; A95-I98 PolarHBondContact O-N 3.47Å; I98-R100 VanDerWaalsContact C-N 3.31Å; I98-R100 PolarHBondContact O-N 3.38Å; I98-C101 WeakPolarHBondContact O-CB 3.45Å; I98-C101 PolarHBondContact O-N 3.48Å; I98-C101 VanDerWaalsContact O-N 3.09Å; I98-I102 HydrophobicContact CG2-CD1 3.84Å; I98-I102 HydrophobicContact CG2-CG1 4.4Å; I98-I102 WeakPolarHBondContact O-CG1 3.41Å; I98-I102 PolarHBondContact O-N 3.13Å; I98-P144 HydrophobicContact CD1-CB 3.86Å; I98-P144 HydrophobicContact CD1-CG 3.83Å; I98-E208 HydrophobicContact CD1-CG 3.93Å; I98-L209 HydrophobicContact CD1-CD2 3.9Å; I98-L209 HydrophobicContact CG1-CD2 3.85Å; I98-L212 HydrophobicContact CG2-CD2 4.27Å
99S96.9Very high95.7Very high73 Ų7371.3 Ų71.351%0.5135%0.352SS..Hα-helixtrans-57.9-43.1178.9-58.80000112.3A95 S96 L97 I102 K103A95-S99 WeakPolarHBondContact O-CB 3.31Å; A95-S99 PolarHBondContact O-N 2.49Å; A95-S99 PolarHBondContact O-OG 2.81Å; S96-S99 PolarHBondContact O-N 3.4Å; L97-S99 VanDerWaalsContact C-N 3.34Å; L97-S99 PolarHBondContact O-N 2.97Å; S99-I102 PolarHBondContact O-N 2.89Å; S99-K103 PolarHBondContact O-N 3.24Å; S99-K103 VanDerWaalsContact O-N 3.09Å
100R96.9Very high95.9Very high123 Ų12372.5 Ų72.546%0.46436%0.356SS..Hα-helixtrans-63.4-45.3174.6176.4174.556.2167.4-4111.9S96 L97 I98 I102 K103 E104S96-R100 WeakPolarHBondContact O-CB 3.24Å; S96-R100 PolarHBondContact O-N 3.46Å; L97-R100 PolarHBondContact O-N 2.9Å; I98-R100 VanDerWaalsContact C-N 3.31Å; I98-R100 PolarHBondContact O-N 3.38Å; R100-I102 VanDerWaalsContact C-N 3.32Å; R100-I102 PolarHBondContact O-N 3.43Å; R100-K103 PolarHBondContact O-N 2.99Å; R100-E104 WeakPolarHBondContact CD-OE1 3.43Å; R100-E104 HydrophobicContact CG-CG 4.35Å; R100-E104 WeakPolarHBondContact CG-OE1 3.38Å; R100-E104 WeakPolarHBondContact O-CB 3.28Å; R100-E104 WeakPolarHBondContact O-CG 3.22Å; R100-E104 PolarHBondContact O-N 3.42Å
101C97.4Very high96Very high0 Ų072.6 Ų72.60%036%0.356CS..Hα-helixtrans-60.9-39.8178.1-69.10000112.2L97 I98 E104 R105 R106 L212L97-C101 PolarHBondContact O-N 3.46Å; L97-C101 PolarHBondContact O-SG 3.25Å; I98-C101 WeakPolarHBondContact O-CB 3.45Å; I98-C101 PolarHBondContact O-N 3.48Å; I98-C101 VanDerWaalsContact O-N 3.09Å; C101-E104 CarbonylContact O-C 3.57Å; C101-E104 PolarHBondContact O-N 3.13Å; C101-R105 PolarHBondContact O-N 3.46Å; C101-R106 VanDerWaalsContact CB-O 3.24Å; C101-R106 WeakPolarHBondContact CB-O 3.39Å; C101-R106 PolarHBondContact O-N 3.11Å; C101-L212 HydrophobicContact CB-CD1 4.05Å; C101-L212 HydrophobicContact CB-CD2 3.78Å
102I97.6Very high96.2Very high89 Ų8971.3 Ų71.346%0.45634%0.339SS..Hα-helixtrans-61.2-48.7174-67.2166.6000110.5I98 S99 R100 E104 R105 L212I98-I102 HydrophobicContact CG2-CD1 3.84Å; I98-I102 HydrophobicContact CG2-CG1 4.4Å; I98-I102 WeakPolarHBondContact O-CG1 3.41Å; I98-I102 PolarHBondContact O-N 3.13Å; S99-I102 PolarHBondContact O-N 2.89Å; R100-I102 VanDerWaalsContact C-N 3.32Å; R100-I102 PolarHBondContact O-N 3.43Å; I102-E104 VanDerWaalsContact C-N 3.31Å; I102-E104 PolarHBondContact O-N 3.47Å; I102-R105 PolarHBondContact O-N 3.09Å; I102-L212 HydrophobicContact CD1-CB 4.32Å; I102-L212 WeakPolarHBondContact CD1-O 3.41Å; I102-L212 HydrophobicContact CG1-CB 3.75Å; I102-L212 HydrophobicContact CG1-CD1 4.16Å; I102-L212 HydrophobicContact CG1-CG 4.44Å
103K97.7Very high96.4Very high187 Ų18769.9 Ų69.981%0.81333%0.325SS*.Hα-helixtrans-61.3-40.4179.2-175.1179.4177.9-178.70112.1S99 R100 R105S99-K103 PolarHBondContact O-N 3.24Å; S99-K103 VanDerWaalsContact O-N 3.09Å; R100-K103 PolarHBondContact O-N 2.99Å; K103-R105 PolarHBondContact O-N 3.35Å
104E97.6Very high96.5Very high99 Ų9968.6 Ų68.646%0.46332%0.318SS..THydrogen-bonded Turntrans-77.8-6.3177.1-69.9172.7-169.500113.3R100 C101 I102 R106R100-E104 WeakPolarHBondContact CD-OE1 3.43Å; R100-E104 HydrophobicContact CG-CG 4.35Å; R100-E104 WeakPolarHBondContact CG-OE1 3.38Å; R100-E104 WeakPolarHBondContact O-CB 3.28Å; R100-E104 WeakPolarHBondContact O-CG 3.22Å; R100-E104 PolarHBondContact O-N 3.42Å; C101-E104 CarbonylContact O-C 3.57Å; C101-E104 PolarHBondContact O-N 3.13Å; I102-E104 VanDerWaalsContact C-N 3.31Å; I102-E104 PolarHBondContact O-N 3.47Å; E104-R106 HydrophobicContact CB-CB 4.16Å; E104-R106 PolarHBondContact O-N 3.06Å; E104-R106 IonicContact OE2-CZ 3.68Å; E104-R106 IonicContact OE2-NE 2.73Å; E104-R106 PolarHBondContact OE2-NE 3.13Å; E104-R106 IonicContact OE2-NH2 3.66Å; E104-R106 PolarHBondContact OE2-NH2 2.78Å
105R96.7Very high96.4Very high231 Ų23172.5 Ų72.587%0.87233%0.332SS*.THydrogen-bonded Turntrans51.538.1-173.3-57-176.7178.9-164.3-0.6112.8C101 I102 K103C101-R105 PolarHBondContact O-N 3.46Å; I102-R105 PolarHBondContact O-N 3.09Å; K103-R105 PolarHBondContact O-N 3.35Å
106R97.3Very high96.5Very high111 Ų11171 Ų7142%0.41932%0.32SS..  trans-124.4127.9-173.8-177.1177.56181.24.4110C101 E104C101-R106 VanDerWaalsContact CB-O 3.24Å; C101-R106 WeakPolarHBondContact CB-O 3.39Å; C101-R106 PolarHBondContact O-N 3.11Å; E104-R106 HydrophobicContact CB-CB 4.16Å; E104-R106 PolarHBondContact O-N 3.06Å; E104-R106 IonicContact OE2-CZ 3.68Å; E104-R106 IonicContact OE2-NE 2.73Å; E104-R106 PolarHBondContact OE2-NE 3.13Å; E104-R106 IonicContact OE2-NH2 3.66Å; E104-R106 PolarHBondContact OE2-NH2 2.78Å
107Y97.9Very high96.6Very high97 Ų9767.9 Ų67.938%0.3830%0.298SS..PPolyproline II helixtrans-81.6151.1173.7-71-74.9000112.1C210 L212 P237 R239Y107-C210 WeakPolarHBondContact CD1-O 3.3Å; Y107-C210 WeakPolarHBondContact CE1-O 3.48Å; Y107-L212 HydrophobicContact CD1-CD1 3.88Å; Y107-L212 HydrophobicContact CD1-CG 3.89Å; Y107-L212 HydrophobicContact CE1-CD1 4.1Å; Y107-L212 HydrophobicContact CE1-CG 4.07Å; Y107-P237 HydrophobicContact CD1-CG 4.39Å; Y107-P237 HydrophobicContact CE1-CG 3.77Å; Y107-R239 VanDerWaalsContact CB-CZ 3.44Å
108L97.6Very high96.6Very high8 Ų867.3 Ų67.34%0.04230%0.295CS..PPolyproline II helixtrans-71.4144.4176.7-70.9169.9000111.6L97 F112 I113 L209 R239 Y240L97-L108 HydrophobicContact CD1-CD2 4.21Å; L97-L108 HydrophobicContact CD2-CD1 4.15Å; L97-L108 HydrophobicContact CD2-CD2 4Å; L97-L108 HydrophobicContact CG-CD2 4.19Å; L108-F112 HydrophobicContact CB-CD1 4.42Å; L108-F112 HydrophobicContact CD1-CD1 4.2Å; L108-F112 HydrophobicContact CD1-CE1 4.13Å; L108-F112 HydrophobicContact CD2-CD1 4.07Å; L108-F112 HydrophobicContact CD2-CE1 4.23Å; L108-F112 HydrophobicContact CG-CD1 4.48Å; L108-I113 HydrophobicContact CB-CD1 4.2Å; L108-I113 HydrophobicContact CB-CG1 4.19Å; L108-L209 HydrophobicContact CD1-CB 4.1Å; L108-L209 HydrophobicContact CD1-CD2 3.67Å; L108-L209 HydrophobicContact CD1-CG 4.46Å; L108-R239 PolarHBondContact O-NH1 3.33Å; L108-Y240 WeakPolarHBondContact O-CE1 3.35Å; L108-Y240 PolarHBondContact O-OH 3.36Å
109E97.3Very high96.5Very high131 Ų13167.2 Ų67.261%0.61230%0.295SS*.PPolyproline II helixtrans-66.8141.7175.9-68.3175.2-170.100111.5Q111 F112 I113E109-Q111 VanDerWaalsContact C-N 3.26Å; E109-Q111 PolarHBondContact O-N 3.01Å; E109-F112 WeakPolarHBondContact O-CB 3.13Å; E109-F112 PolarHBondContact O-N 2.64Å; E109-I113 PolarHBondContact O-N 2.9Å
110E96.9Very high96.4Very high39 Ų3963.8 Ų63.818%0.18227%0.271CS..Hα-helixtrans-56.5-42.6-179.7-173.7165.6149.200111.6F112 I113 L114 Y240 S241 L244E110-F112 PolarHBondContact O-N 3.28Å; E110-I113 CarbonylContact O-C 3.57Å; E110-I113 WeakPolarHBondContact O-CA 3.3Å; E110-I113 WeakPolarHBondContact O-CB 3.24Å; E110-I113 PolarHBondContact O-N 3.36Å; E110-L114 HydrophobicContact CG-CD1 4.22Å; E110-L114 HydrophobicContact CG-CG 4.16Å; E110-L114 WeakPolarHBondContact O-CG 3.29Å; E110-L114 PolarHBondContact O-N 3.26Å; E110-Y240 HydrophobicContact CB-CD1 4.08Å; E110-Y240 HydrophobicContact CG-CD1 4.37Å; E110-Y240 VanDerWaalsContact OE2-CA 3.24Å; E110-Y240 WeakPolarHBondContact OE2-CA 3.37Å; E110-S241 VanDerWaalsContact OE1-CB 3.23Å; E110-S241 WeakPolarHBondContact OE1-CB 3.44Å; E110-S241 PolarHBondContact OE1-OG 3.04Å; E110-S241 PolarHBondContact OE2-N 3.5Å; E110-L244 HydrophobicContact CG-CD2 3.92Å
111Q94.4Very high96.4Very high118 Ų11858 Ų5855%0.55125%0.249SC*.Hα-helixtrans-59.1-32.5177.7-66.3-58.7-26.500113.3E109 R115E109-Q111 VanDerWaalsContact C-N 3.26Å; E109-Q111 PolarHBondContact O-N 3.01Å; Q111-R115 WeakPolarHBondContact O-CG 3.06Å; Q111-R115 PolarHBondContact O-N 3.48Å; Q111-R115 PolarHBondContact O-NE 3.13Å
112F94.7Very high96.2Very high14 Ų1458.9 Ų58.96%0.06125%0.254CS..Hα-helixtrans-68.4-45.5171.8175.9-99000111.1L94 L97 L108 E109 E110 L114 R115 V116 L149 Q153L94-F112 HydrophobicContact CD2-CZ 4.36Å; L97-F112 HydrophobicContact CD2-CE1 3.57Å; L97-F112 HydrophobicContact CD2-CZ 3.67Å; L108-F112 HydrophobicContact CB-CD1 4.42Å; L108-F112 HydrophobicContact CD1-CD1 4.2Å; L108-F112 HydrophobicContact CD1-CE1 4.13Å; L108-F112 HydrophobicContact CD2-CD1 4.07Å; L108-F112 HydrophobicContact CD2-CE1 4.23Å; L108-F112 HydrophobicContact CG-CD1 4.48Å; E109-F112 WeakPolarHBondContact O-CB 3.13Å; E109-F112 PolarHBondContact O-N 2.64Å; E110-F112 PolarHBondContact O-N 3.28Å; F112-L114 VanDerWaalsContact C-N 3.33Å; F112-L114 PolarHBondContact O-N 2.97Å; F112-R115 PolarHBondContact O-N 2.82Å; F112-V116 HydrophobicContact CD1-CG2 4.14Å; F112-V116 HydrophobicContact CE1-CG2 3.67Å; F112-V116 HydrophobicContact CE2-CG2 4.2Å; F112-V116 HydrophobicContact CZ-CG2 3.71Å; F112-V116 WeakPolarHBondContact O-CG2 3.44Å; F112-V116 PolarHBondContact O-N 3.36Å; F112-L149 HydrophobicContact CZ-CD2 4.24Å; F112-Q153 HydrophobicContact CE2-CB 4.26Å
113I96.8Very high95.9Very high0 Ų054.7 Ų54.70%023%0.232CC..Hα-helixtrans-61.8-40.6179.6-58.4174000111.1L108 E109 E110 V116 M117 L206 L209 C210 Y240 L244L108-I113 HydrophobicContact CB-CD1 4.2Å; L108-I113 HydrophobicContact CB-CG1 4.19Å; E109-I113 PolarHBondContact O-N 2.9Å; E110-I113 CarbonylContact O-C 3.57Å; E110-I113 WeakPolarHBondContact O-CA 3.3Å; E110-I113 WeakPolarHBondContact O-CB 3.24Å; E110-I113 PolarHBondContact O-N 3.36Å; I113-V116 WeakPolarHBondContact O-CB 3.44Å; I113-V116 PolarHBondContact O-N 3.12Å; I113-M117 WeakPolarHBondContact O-CB 3.48Å; I113-M117 PolarHBondContact O-N 3.34Å; I113-L206 HydrophobicContact CG2-CD2 4.26Å; I113-L209 HydrophobicContact CD1-CB 4.42Å; I113-L209 HydrophobicContact CG1-CB 4.27Å; I113-C210 HydrophobicContact CD1-CB 4.44Å; I113-Y240 HydrophobicContact CD1-CD1 4.27Å; I113-Y240 HydrophobicContact CD1-CE1 3.51Å; I113-L244 HydrophobicContact CG2-CD2 4.41Å
114L95.7Very high95.7Very high5 Ų545.8 Ų45.83%0.02619%0.193CC..Hα-helixtrans-65.5-39176.2-62.4-176.1000112.3E110 F112 M117 A118 L244 L270 L271E110-L114 HydrophobicContact CG-CD1 4.22Å; E110-L114 HydrophobicContact CG-CG 4.16Å; E110-L114 WeakPolarHBondContact O-CG 3.29Å; E110-L114 PolarHBondContact O-N 3.26Å; F112-L114 VanDerWaalsContact C-N 3.33Å; F112-L114 PolarHBondContact O-N 2.97Å; L114-M117 HydrophobicContact CD2-CE 4.26Å; L114-M117 WeakPolarHBondContact O-CB 3.32Å; L114-M117 PolarHBondContact O-N 2.88Å; L114-A118 WeakPolarHBondContact O-CB 3.49Å; L114-A118 PolarHBondContact O-N 3.33Å; L114-L244 HydrophobicContact CD2-CD1 4.17Å; L114-L270 HydrophobicContact CD1-CD1 3.87Å; L114-L270 HydrophobicContact CD1-CG 4.07Å; L114-L270 HydrophobicContact CD2-CD1 4.08Å; L114-L270 HydrophobicContact CD2-CD2 3.6Å; L114-L270 HydrophobicContact CD2-CG 3.6Å; L114-L270 HydrophobicContact CG-CG 4.48Å; L114-L271 HydrophobicContact CB-CD2 4.1Å; L114-L271 HydrophobicContact CD2-CD2 4.08Å
115R93.8Very high95.4Very high82 Ų8244.9 Ų44.931%0.30919%0.188SC..Hα-helixtrans-63.1-43.4172.3-74.3-174.8-61.6173.83.9112Q111 F112 M117 A118 Q119Q111-R115 WeakPolarHBondContact O-CG 3.06Å; Q111-R115 PolarHBondContact O-N 3.48Å; Q111-R115 PolarHBondContact O-NE 3.13Å; F112-R115 PolarHBondContact O-N 2.82Å; R115-M117 VanDerWaalsContact C-N 3.34Å; R115-A118 PolarHBondContact O-N 2.82Å; R115-Q119 WeakPolarHBondContact O-CB 3.4Å; R115-Q119 WeakPolarHBondContact O-CG 3.45Å; R115-Q119 PolarHBondContact O-N 3Å
116V95.7Very high95Very high2 Ų237.6 Ų37.61%0.01216%0.163CC..Hα-helixtrans-59.1-47.6173.9173.50000110.2L94 F112 I113 Q119 L120 V155 L206 L209L94-V116 HydrophobicContact CD1-CG1 4.1Å; F112-V116 HydrophobicContact CD1-CG2 4.14Å; F112-V116 HydrophobicContact CE1-CG2 3.67Å; F112-V116 HydrophobicContact CE2-CG2 4.2Å; F112-V116 HydrophobicContact CZ-CG2 3.71Å; F112-V116 WeakPolarHBondContact O-CG2 3.44Å; F112-V116 PolarHBondContact O-N 3.36Å; I113-V116 WeakPolarHBondContact O-CB 3.44Å; I113-V116 PolarHBondContact O-N 3.12Å; V116-Q119 PolarHBondContact O-N 2.89Å; V116-L120 HydrophobicContact CG1-CD1 3.69Å; V116-L120 HydrophobicContact CG1-CG 4.15Å; V116-L120 WeakPolarHBondContact O-CB 3.47Å; V116-L120 VanDerWaalsContact O-CG 3.31Å; V116-L120 WeakPolarHBondContact O-CG 3.38Å; V116-L120 PolarHBondContact O-N 3.48Å; V116-V155 HydrophobicContact CB-CG1 4.3Å; V116-V155 HydrophobicContact CG1-CG1 4.1Å; V116-V155 HydrophobicContact CG2-CG1 3.75Å; V116-L206 HydrophobicContact CG1-CD2 4.27Å; V116-L209 HydrophobicContact CB-CD1 4.28Å; V116-L209 HydrophobicContact CG1-CD1 3.79Å; V116-L209 HydrophobicContact CG2-CD1 4.42Å
117M97Very high94.4Very high0 Ų032.3 Ų32.30%014%0.143CC..Hα-helixtrans-57-54.6177.8-171.7-178.6-50.600111.2I113 L114 R115 Q119 L120 T121 L206 L244 L247 I265 L271I113-M117 WeakPolarHBondContact O-CB 3.48Å; I113-M117 PolarHBondContact O-N 3.34Å; L114-M117 HydrophobicContact CD2-CE 4.26Å; L114-M117 WeakPolarHBondContact O-CB 3.32Å; L114-M117 PolarHBondContact O-N 2.88Å; R115-M117 VanDerWaalsContact C-N 3.34Å; M117-Q119 PolarHBondContact O-N 2.81Å; M117-L120 PolarHBondContact O-N 3.07Å; M117-T121 VanDerWaalsContact O-CB 3.28Å; M117-T121 WeakPolarHBondContact O-CB 3.4Å; M117-T121 PolarHBondContact O-N 2.79Å; M117-T121 PolarHBondContact O-OG1 2.9Å; M117-L206 HydrophobicContact CB-CD1 4.19Å; M117-L206 HydrophobicContact CB-CD2 3.83Å; M117-L206 HydrophobicContact CE-CD1 3.87Å; M117-L206 HydrophobicContact CE-CD2 4.39Å; M117-L206 HydrophobicContact CG-CD1 3.75Å; M117-L206 HydrophobicContact CG-CD2 4.34Å; M117-L206 HydrophobicContact SD-CD1 4.31Å; M117-L244 HydrophobicContact CE-CD1 3.29Å; M117-L247 HydrophobicContact CE-CD2 4.22Å; M117-L247 HydrophobicContact SD-CD2 3.51Å; M117-L247 VanDerWaalsContact SD-CD2 3.51Å; M117-I265 HydrophobicContact CG-CG2 4.47Å; M117-I265 HydrophobicContact SD-CG2 4.37Å; M117-L271 HydrophobicContact CB-CD2 4.19Å; M117-L271 HydrophobicContact CG-CD1 3.86Å; M117-L271 HydrophobicContact CG-CD2 4.26Å; M117-L271 HydrophobicContact SD-CD1 3.73Å; M117-L271 HydrophobicContact SD-CD2 3.95Å; M117-L271 HydrophobicContact SD-CG 4.15Å
118A95.4Very high93.8Very high0 Ų028.9 Ų28.90%013%0.131CC..Hα-helixtrans-57.2-49.3-179.300000112L114 R115 T121 L122 L271 V275L114-A118 WeakPolarHBondContact O-CB 3.49Å; L114-A118 PolarHBondContact O-N 3.33Å; R115-A118 PolarHBondContact O-N 2.82Å; A118-T121 PolarHBondContact O-N 2.87Å; A118-L122 WeakPolarHBondContact O-CB 3.28Å; A118-L122 VanDerWaalsContact O-CG 3.24Å; A118-L122 WeakPolarHBondContact O-CG 3.24Å; A118-L122 PolarHBondContact O-N 2.81Å; A118-L271 HydrophobicContact CB-CD2 4.42Å; A118-V275 HydrophobicContact CB-CG2 4Å
119Q95.4Very high92.7Very high3 Ų331.3 Ų31.31%0.01415%0.149CC..Hα-helixtrans-68.8-38.2-176.8-72.6-175.71200112.9N66 R115 V116 M117 A123 N154 V155 E278N66-Q119 HydrophobicContact CB-CB 4.33Å; N66-Q119 WeakPolarHBondContact CB-O 3.23Å; N66-Q119 WeakPolarHBondContact ND2-CB 3.26Å; N66-Q119 WeakPolarHBondContact ND2-CG 3.4Å; N66-Q119 PolarHBondContact ND2-OE1 2.97Å; N66-Q119 VanDerWaalsContact ND2-OE1 3.16Å; R115-Q119 WeakPolarHBondContact O-CB 3.4Å; R115-Q119 WeakPolarHBondContact O-CG 3.45Å; R115-Q119 PolarHBondContact O-N 3Å; V116-Q119 PolarHBondContact O-N 2.89Å; M117-Q119 PolarHBondContact O-N 2.81Å; Q119-A123 PolarHBondContact O-N 2.88Å; Q119-N154 PolarHBondContact NE2-OD1 2.87Å; Q119-V155 HydrophobicContact CB-CG2 3.28Å; Q119-V155 HydrophobicContact CG-CG2 4.25Å; Q119-E278 HydrophobicContact CG-CG 3.83Å; Q119-E278 PolarHBondContact NE2-OE1 3.49Å; Q119-E278 PolarHBondContact NE2-OE2 2.75Å
120L95.9Very high91.2Very high1 Ų127.7 Ų27.71%0.00513%0.129CC..Hα-helixtrans-70.6-40.4174.5-70.1-176.9000112.1V116 M117 L122 A123 L124 I147 V155 L157 L202 L205V116-L120 HydrophobicContact CG1-CD1 3.69Å; V116-L120 HydrophobicContact CG1-CG 4.15Å; V116-L120 WeakPolarHBondContact O-CB 3.47Å; V116-L120 VanDerWaalsContact O-CG 3.31Å; V116-L120 WeakPolarHBondContact O-CG 3.38Å; V116-L120 PolarHBondContact O-N 3.48Å; M117-L120 PolarHBondContact O-N 3.07Å; L120-L122 VanDerWaalsContact C-N 3.31Å; L120-L122 PolarHBondContact O-N 3.13Å; L120-A123 WeakPolarHBondContact O-CB 3.21Å; L120-A123 PolarHBondContact O-N 2.87Å; L120-L124 WeakPolarHBondContact O-CG 3.34Å; L120-L124 PolarHBondContact O-N 3.46Å; L120-I147 HydrophobicContact CD1-CD1 4.3Å; L120-I147 HydrophobicContact CD1-CG1 4.24Å; L120-I147 HydrophobicContact CD1-CG2 4.33Å; L120-I147 HydrophobicContact CD2-CD1 3.81Å; L120-I147 HydrophobicContact CD2-CG1 4.36Å; L120-I147 HydrophobicContact CD2-CG2 3.88Å; L120-V155 HydrophobicContact CD2-CB 4.37Å; L120-V155 HydrophobicContact CD2-CG2 4.06Å; L120-V155 HydrophobicContact CG-CG2 4.05Å; L120-L157 HydrophobicContact CD2-CB 4.25Å; L120-L202 HydrophobicContact CB-CD1 3.83Å; L120-L202 HydrophobicContact CD1-CD1 3.64Å; L120-L202 HydrophobicContact CG-CD1 4.4Å; L120-L205 HydrophobicContact CD1-CD1 4.5Å; L120-L205 HydrophobicContact CD1-CD2 4Å
121T95.4Very high88.9Confident0 Ų031.6 Ų31.60%016%0.161CC..Hα-helixtrans-64.2-38.2175.5-590000111M117 A118 L124 K125 V262 I265 L266M117-T121 VanDerWaalsContact O-CB 3.28Å; M117-T121 WeakPolarHBondContact O-CB 3.4Å; M117-T121 PolarHBondContact O-N 2.79Å; M117-T121 PolarHBondContact O-OG1 2.9Å; A118-T121 PolarHBondContact O-N 2.87Å; T121-L124 PolarHBondContact O-N 3.4Å; T121-K125 PolarHBondContact O-N 2.79Å; T121-V262 HydrophobicContact CG2-CB 4.35Å; T121-V262 HydrophobicContact CG2-CG1 3.67Å; T121-V262 WeakPolarHBondContact O-CG1 3.26Å; T121-I265 HydrophobicContact CG2-CB 3.98Å; T121-I265 HydrophobicContact CG2-CG2 3.85Å; T121-L266 HydrophobicContact CG2-CD1 4.18Å; T121-L266 HydrophobicContact CG2-CD2 3.71Å; T121-L266 HydrophobicContact CG2-CG 3.59Å
122L93.4Very high87Confident20 Ų2030.1 Ų30.111%0.10516%0.157CC..Hα-helixtrans-63.3-41.6171-73.4168000112.3A118 L120 K125 E126 L266 E278A118-L122 WeakPolarHBondContact O-CB 3.28Å; A118-L122 VanDerWaalsContact O-CG 3.24Å; A118-L122 WeakPolarHBondContact O-CG 3.24Å; A118-L122 PolarHBondContact O-N 2.81Å; L120-L122 VanDerWaalsContact C-N 3.31Å; L120-L122 PolarHBondContact O-N 3.13Å; L122-K125 WeakPolarHBondContact O-CB 3.26Å; L122-K125 PolarHBondContact O-N 2.81Å; L122-E126 PolarHBondContact O-N 3.45Å; L122-E126 VanDerWaalsContact O-N 3.12Å; L122-L266 HydrophobicContact CD2-CD1 4.01Å; L122-L266 HydrophobicContact CD2-CD2 4.06Å; L122-L266 HydrophobicContact CG-CD2 3.97Å; L122-E278 HydrophobicContact CD1-CB 3.95Å
123A92.3Very high84.9Confident0 Ų033.2 Ų33.20%019%0.193CC..Hα-helixtrans-62.1-43174.800000112N66 I67 Q119 L120 K125 E126 C127 L157N66-A123 HydrophobicContact CB-CB 4.07Å; N66-A123 WeakPolarHBondContact O-CB 3.44Å; I67-A123 HydrophobicContact CG1-CB 3.95Å; Q119-A123 PolarHBondContact O-N 2.88Å; L120-A123 WeakPolarHBondContact O-CB 3.21Å; L120-A123 PolarHBondContact O-N 2.87Å; A123-K125 VanDerWaalsContact C-N 3.33Å; A123-E126 WeakPolarHBondContact O-CB 3.49Å; A123-E126 PolarHBondContact O-N 2.92Å; A123-C127 PolarHBondContact O-N 3.4Å; A123-C127 PolarHBondContact O-SG 3Å; A123-L157 HydrophobicContact CB-CB 4.06Å; A123-L157 HydrophobicContact CB-CD2 3.98Å
124L92.3Very high83.1Confident0 Ų039.3 Ų39.30%022%0.216CC..Hα-helixtrans-65.6-36.8175-70.5178.3000112L120 T121 E126 C127 H128 H139 L142 L157 D198 L202 V262L120-L124 WeakPolarHBondContact O-CG 3.34Å; L120-L124 PolarHBondContact O-N 3.46Å; T121-L124 PolarHBondContact O-N 3.4Å; L124-E126 VanDerWaalsContact C-N 3.3Å; L124-E126 PolarHBondContact O-N 2.9Å; L124-C127 WeakPolarHBondContact O-CB 3.48Å; L124-C127 PolarHBondContact O-N 2.73Å; L124-H128 WeakPolarHBondContact O-CB 3.31Å; L124-H128 VanDerWaalsContact O-CG 3.24Å; L124-H128 PolarHBondContact O-N 3.41Å; L124-H139 HydrophobicContact CD2-CB 4.35Å; L124-L142 HydrophobicContact CD1-CD1 4.09Å; L124-L142 HydrophobicContact CD2-CD1 4.12Å; L124-L157 HydrophobicContact CD2-CD2 4.03Å; L124-D198 HydrophobicContact CD1-CB 4.4Å; L124-D198 HydrophobicContact CD2-CB 4.29Å; L124-L202 HydrophobicContact CD1-CB 4.43Å; L124-L202 HydrophobicContact CD1-CD2 3.9Å; L124-V262 HydrophobicContact CB-CG2 4.28Å
125K91.5Very high81.6Confident81 Ų8143 Ų4335%0.35225%0.247SC..Hα-helixtrans-55.3-47.2172.9-164.4-179.9176.2178.90111.6T121 L122 A123 C127 H128 S129 V262 L266T121-K125 PolarHBondContact O-N 2.79Å; L122-K125 WeakPolarHBondContact O-CB 3.26Å; L122-K125 PolarHBondContact O-N 2.81Å; A123-K125 VanDerWaalsContact C-N 3.33Å; K125-C127 PolarHBondContact O-N 3.28Å; K125-H128 PolarHBondContact O-N 2.89Å; K125-S129 WeakPolarHBondContact O-CA 3.41Å; K125-S129 WeakPolarHBondContact O-CB 3.09Å; K125-S129 PolarHBondContact O-N 2.91Å; K125-V262 HydrophobicContact CB-CG1 3.48Å; K125-V262 VanDerWaalsContact CB-CG1 3.48Å; K125-V262 HydrophobicContact CD-CG1 4.48Å; K125-V262 HydrophobicContact CG-CG1 3.89Å; K125-L266 HydrophobicContact CD-CD1 3.87Å
126E88.2Confident80.6Confident77 Ų7742.7 Ų42.736%0.3626%0.255SS..Hα-helixtrans-59.8-35.7177.1-17770.2-170.700111.9H64 I67 L122 A123 L124H64-E126 HydrophobicContact CB-CB 4.38Å; H64-E126 HydrophobicContact CB-CG 4.07Å; I67-E126 HydrophobicContact CD1-CB 4.3Å; I67-E126 HydrophobicContact CD1-CG 4.22Å; L122-E126 PolarHBondContact O-N 3.45Å; L122-E126 VanDerWaalsContact O-N 3.12Å; A123-E126 WeakPolarHBondContact O-CB 3.49Å; A123-E126 PolarHBondContact O-N 2.92Å; L124-E126 VanDerWaalsContact C-N 3.3Å; L124-E126 PolarHBondContact O-N 2.9Å
127C85.7Confident79.7Confident0 Ų043 Ų430%026%0.257CS..Hα-helixtrans-77-40.4-178.2-58.80000111.9A123 L124 K125 V137 F160A123-C127 PolarHBondContact O-N 3.4Å; A123-C127 PolarHBondContact O-SG 3Å; L124-C127 WeakPolarHBondContact O-CB 3.48Å; L124-C127 PolarHBondContact O-N 2.73Å; K125-C127 PolarHBondContact O-N 3.28Å; C127-V137 CarbonylContact C-O 3.57Å; C127-V137 HydrophobicContact CB-CB 4.18Å; C127-V137 WeakPolarHBondContact CB-O 3.25Å; C127-V137 WeakPolarHBondContact O-CA 3.4Å; C127-V137 WeakPolarHBondContact O-CB 3.4Å; C127-V137 PolarHBondContact O-N 3.05Å; C127-F160 HydrophobicContact CB-CE1 4.34Å; C127-F160 WeakPolarHBondContact SG-CE1 3.5Å; C127-F160 VanDerWaalsContact SG-CZ 3.51Å
128H85.2Confident78.8Confident26 Ų2644.4 Ų44.412%0.1226%0.264CS..Hα-helixtrans-80.5-33.3-177.8-61.2169.9000112.3L124 K125 R130 T136 V137 D198L124-H128 WeakPolarHBondContact O-CB 3.31Å; L124-H128 VanDerWaalsContact O-CG 3.24Å; L124-H128 PolarHBondContact O-N 3.41Å; K125-H128 PolarHBondContact O-N 2.89Å; H128-R130 PolarHBondContact O-N 3.03Å; H128-T136 HydrophobicContact CB-CG2 4.23Å; H128-V137 PolarHBondContact CD2-O 2.99Å; H128-D198 IonicContact CD2-OD2 3.55Å; H128-D198 IonicContact CE1-OD2 2.64Å; H128-D198 IonicContact NE2-OD2 3.7Å; H128-D198 PolarHBondContact NE2-OD2 2.88Å
129S75.1Confident78Confident59 Ų5944.4 Ų44.441%0.41326%0.264SS..  trans-96.481.9-177-162.30000110.7K125K125-S129 WeakPolarHBondContact O-CA 3.41Å; K125-S129 WeakPolarHBondContact O-CB 3.09Å; K125-S129 PolarHBondContact O-N 2.91Å
130R64.2Low77.2Confident55 Ų5548.6 Ų48.621%0.20828%0.279CS..  trans-97.4102.2167.6-70.3-16368.9151.217.5109.8E61 H128 D132E61-R130 IonicContact OE2-CZ 3.94Å; E61-R130 IonicContact OE2-NH1 2.68Å; E61-R130 PolarHBondContact OE2-NH1 3.41Å; E61-R130 IonicContact OE2-NH2 3.78Å; E61-R130 PolarHBondContact OE2-NH2 2.9Å; H128-R130 PolarHBondContact O-N 3.03Å; R130-D132 IonicContact NE-OD1 3.75Å; R130-D132 PolarHBondContact NE-OD1 3.02Å; R130-D132 IonicContact NH2-OD2 3.81Å; R130-D132 PolarHBondContact NH2-OD2 3.26Å; R130-D132 PolarHBondContact O-N 3.21Å
131S48.9Very low76.4Confident121 Ų12150.3 Ų50.385%0.84629%0.289SS*.THydrogen-bonded Turntrans-72.3-5-176.1-30.40000113.9
132D55.1Low76.1Confident86 Ų8650.4 Ų50.446%0.4629%0.289SS..THydrogen-bonded Turntrans-98.717.9-172.365.2-15.9000114R130 R134R130-D132 IonicContact NE-OD1 3.75Å; R130-D132 PolarHBondContact NE-OD1 3.02Å; R130-D132 IonicContact NH2-OD2 3.81Å; R130-D132 PolarHBondContact NH2-OD2 3.26Å; R130-D132 PolarHBondContact O-N 3.21Å; D132-R134 PolarHBondContact O-N 3.23Å; D132-R134 WeakPolarHBondContact OD1-CB 3.47Å; D132-R134 WeakPolarHBondContact OD2-CD 3.46Å; D132-R134 IonicContact OD2-CZ 2.87Å; D132-R134 IonicContact OD2-NE 2.98Å; D132-R134 PolarHBondContact OD2-NE 3.16Å; D132-R134 VanDerWaalsContact OD2-NE 3.17Å
133G50.4Low75.9Confident80 Ų8052 Ų5283%0.82530%0.296SS*.SBendtrans727.4179.300000114.4
134R59Low75.9Confident127 Ų12752.2 Ų52.248%0.47930%0.297SS..  trans-84.3152.5175-64.3-179.3-172.5-171.28.1111E61 D132 T136E61-R134 IonicContact OE1-CZ 2.79Å; E61-R134 IonicContact OE1-NH1 3.61Å; E61-R134 PolarHBondContact OE1-NH1 3.42Å; E61-R134 IonicContact OE1-NH2 2.72Å; E61-R134 IonicContact OE2-CZ 3.48Å; E61-R134 IonicContact OE2-NH1 3.61Å; E61-R134 PolarHBondContact OE2-NH1 3.12Å; D132-R134 PolarHBondContact O-N 3.23Å; D132-R134 WeakPolarHBondContact OD1-CB 3.47Å; D132-R134 WeakPolarHBondContact OD2-CD 3.46Å; D132-R134 IonicContact OD2-CZ 2.87Å; D132-R134 IonicContact OD2-NE 2.98Å; D132-R134 PolarHBondContact OD2-NE 3.16Å; D132-R134 VanDerWaalsContact OD2-NE 3.17Å; R134-T136 PolarHBondContact O-N 2.92Å
135A63.7Low75.8Confident83 Ų8354.2 Ų54.269%0.68631%0.313SS*.  trans-55.5135.8-179.900000112.2V137A135-V137 PolarHBondContact O-N 2.92Å
136T72.8Confident75.8Confident75 Ų7550.9 Ų50.946%0.4630%0.299SS..  trans-44.8129.4170.2-52.30000111.1H128 R134 L138H128-T136 HydrophobicContact CB-CG2 4.23Å; R134-T136 PolarHBondContact O-N 2.92Å; T136-L138 HydrophobicContact CG2-CD2 4.09Å
137V76.3Confident76.1Confident9 Ų947.2 Ų47.26%0.05528%0.282CS..  trans-90.1114.6175.7-176.60000108.7L58 C127 H128 A135L58-V137 HydrophobicContact CD1-CG1 4.2Å; L58-V137 HydrophobicContact CD1-CG2 3.77Å; L58-V137 HydrophobicContact CD2-CG1 3.83Å; L58-V137 HydrophobicContact CD2-CG2 4.19Å; L58-V137 HydrophobicContact CG-CG2 4.14Å; C127-V137 CarbonylContact C-O 3.57Å; C127-V137 HydrophobicContact CB-CB 4.18Å; C127-V137 WeakPolarHBondContact CB-O 3.25Å; C127-V137 WeakPolarHBondContact O-CA 3.4Å; C127-V137 WeakPolarHBondContact O-CB 3.4Å; C127-V137 PolarHBondContact O-N 3.05Å; H128-V137 PolarHBondContact CD2-O 2.99Å; A135-V137 PolarHBondContact O-N 2.92Å
138L78.1Confident76.6Confident29 Ų2950.1 Ų50.115%0.15230%0.295CS..  trans-95.8134.9176.4-59.8171000109.3T136 R140 Y193 E195T136-L138 HydrophobicContact CG2-CD2 4.09Å; L138-R140 HydrophobicContact CB-CG 3.98Å; L138-Y193 HydrophobicContact CB-CD1 3.98Å; L138-Y193 HydrophobicContact CB-CE1 3.84Å; L138-Y193 HydrophobicContact CD1-CD1 3.56Å; L138-Y193 HydrophobicContact CD1-CE1 4.24Å; L138-Y193 HydrophobicContact CD2-CD1 4.31Å; L138-Y193 HydrophobicContact CD2-CE1 4.27Å; L138-Y193 HydrophobicContact CG-CD1 4.13Å; L138-Y193 HydrophobicContact CG-CE1 4.32Å; L138-E195 HydrophobicContact CD2-CB 4.23Å
139H79.5Confident77Confident1 Ų149.3 Ų49.31%0.00529%0.291CS..  trans-75.3-44.5-176.5-174.4-79.1000112.2L124 D141 L142 L157 G158 F160 D198L124-H139 HydrophobicContact CD2-CB 4.35Å; H139-D141 VanDerWaalsContact CE1-C 3.43Å; H139-D141 PolarHBondContact CE1-O 3.07Å; H139-D141 VanDerWaalsContact CE1-O 3.24Å; H139-D141 VanDerWaalsContact ND1-C 3.28Å; H139-D141 PolarHBondContact ND1-N 3.29Å; H139-D141 PolarHBondContact O-N 3.02Å; H139-L142 HydrophobicContact CB-CG 4.21Å; H139-L142 PolarHBondContact ND1-N 3.36Å; H139-L157 VanDerWaalsContact NE2-CD1 3.34Å; H139-L157 WeakPolarHBondContact NE2-CD1 3.31Å; H139-G158 PolarHBondContact NE2-O 2.83Å; H139-F160 AromaticContact CD2-CD1 3.54Å; H139-F160 AromaticContact CD2-CE1 3.49Å; H139-F160 VanDerWaalsContact CD2-CE1 3.49Å; H139-F160 WeakPolarHBondContact CD2-CE1 3.34Å; H139-D198 WeakPolarHBondContact CB-OD1 3.14Å; H139-D198 PolarHBondContact N-OD1 3.44Å; H139-D198 PolarHBondContact N-OD2 2.9Å; H139-D198 VanDerWaalsContact N-OD2 3.15Å
140R78.6Confident77.7Confident90 Ų9047.7 Ų47.734%0.3428%0.278SS..  trans67.7-14.2173.5-52.9177.7-179.7-158.2-1.1117.5L138 Y193 D198L138-R140 HydrophobicContact CB-CG 3.98Å; R140-Y193 HydrophobicContact CB-CE2 4.48Å; R140-Y193 HydrophobicContact CG-CD1 4.13Å; R140-Y193 HydrophobicContact CG-CE1 3.92Å; R140-Y193 HydrophobicContact CG-CE2 4.38Å; R140-Y193 HydrophobicContact CG-CG 4.44Å; R140-D198 PolarHBondContact N-OD1 3.1Å
141D78.8Confident78.7Confident38 Ų3850.7 Ų50.720%0.20330%0.297CS..  trans-135.146.6177.5-166.223.1000112.7H139 K143 N146 A163H139-D141 VanDerWaalsContact CE1-C 3.43Å; H139-D141 PolarHBondContact CE1-O 3.07Å; H139-D141 VanDerWaalsContact CE1-O 3.24Å; H139-D141 VanDerWaalsContact ND1-C 3.28Å; H139-D141 PolarHBondContact ND1-N 3.29Å; H139-D141 PolarHBondContact O-N 3.02Å; D141-K143 PolarHBondContact O-N 3.38Å; D141-K143 IonicContact OD1-NZ 2.73Å; D141-K143 PolarHBondContact OD1-NZ 2.82Å; D141-K143 IonicContact OD2-NZ 3.74Å; D141-K143 PolarHBondContact OD2-NZ 3.04Å; D141-N146 VanDerWaalsContact CG-ND2 3.29Å; D141-N146 PolarHBondContact O-ND2 3.4Å; D141-N146 PolarHBondContact OD2-ND2 3.34Å; D141-A163 HydrophobicContact CB-CB 4.42Å
142L88.5Confident80.4Confident2 Ų251.8 Ų51.81%0.0129%0.287CS..  trans-71111.2175.3-83.8173.3000110.3L124 H139 I147 L157 Y182 D198 L202L124-L142 HydrophobicContact CD1-CD1 4.09Å; L124-L142 HydrophobicContact CD2-CD1 4.12Å; H139-L142 HydrophobicContact CB-CG 4.21Å; H139-L142 PolarHBondContact ND1-N 3.36Å; L142-I147 HydrophobicContact CD2-CD1 4.11Å; L142-L157 HydrophobicContact CD2-CD1 3.41Å; L142-L157 VanDerWaalsContact CD2-CD1 3.41Å; L142-L157 HydrophobicContact CD2-CD2 4.31Å; L142-Y182 WeakPolarHBondContact O-CB 3.31Å; L142-D198 HydrophobicContact CD1-CB 4.02Å; L142-D198 WeakPolarHBondContact CD1-O 3.42Å; L142-L202 HydrophobicContact CD1-CB 4.31Å
143K89.9Confident81.8Confident54 Ų5452.9 Ų52.924%0.23529%0.289CS..  trans-153.5158.1175.564-176.3177.1-127.40110.5D141 A145 N146 Y182D141-K143 PolarHBondContact O-N 3.38Å; D141-K143 IonicContact OD1-NZ 2.73Å; D141-K143 PolarHBondContact OD1-NZ 2.82Å; D141-K143 IonicContact OD2-NZ 3.74Å; D141-K143 PolarHBondContact OD2-NZ 3.04Å; K143-A145 HydrophobicContact CD-CB 4.49Å; K143-A145 HydrophobicContact CG-CB 4.37Å; K143-A145 PolarHBondContact O-N 2.98Å; K143-A145 VanDerWaalsContact O-N 3.12Å; K143-N146 WeakPolarHBondContact CE-ND2 3.14Å; K143-N146 HydrophobicContact CG-CB 4.16Å; K143-N146 PolarHBondContact O-N 3.47Å; K143-Y182 HydrophobicContact CB-CD2 3.63Å; K143-Y182 HydrophobicContact CB-CE2 3.62Å; K143-Y182 HydrophobicContact CB-CG 4.23Å
144P93.1Very high83.6Confident3 Ų349.8 Ų49.82%0.01925%0.254CS..G310 helixtrans-54.4-35.2-177.5-26.833.9000114.4L94 A95 I98 N146 I147 Y182 L205 E208L94-P144 HydrophobicContact CB-CB 3.88Å; L94-P144 PolarHBondContact N-O 3.27Å; L94-P144 VanDerWaalsContact N-O 3.17Å; A95-P144 HydrophobicContact CB-CB 3.89Å; A95-P144 PolarHBondContact N-O 3.49Å; I98-P144 HydrophobicContact CD1-CB 3.86Å; I98-P144 HydrophobicContact CD1-CG 3.83Å; P144-N146 PolarHBondContact O-N 2.93Å; P144-I147 PolarHBondContact O-N 2.95Å; P144-I147 VanDerWaalsContact O-N 3.16Å; P144-Y182 WeakPolarHBondContact CD-OH 3.5Å; P144-Y182 HydrophobicContact CG-CE1 4.18Å; P144-Y182 WeakPolarHBondContact CG-OH 3.49Å; P144-L205 HydrophobicContact CG-CD1 4.45Å; P144-L205 HydrophobicContact CG-CG 4.29Å; P144-E208 VanDerWaalsContact CG-OE2 3.31Å; P144-E208 WeakPolarHBondContact CG-OE2 3.28Å
145A89.7Confident85.3Confident42 Ų4243.8 Ų43.835%0.34723%0.231SC..G310 helixtrans-66.7-18178.400000114.1A95 K143A95-A145 HydrophobicContact CB-CB 4.2Å; K143-A145 HydrophobicContact CD-CB 4.49Å; K143-A145 HydrophobicContact CG-CB 4.37Å; K143-A145 PolarHBondContact O-N 2.98Å; K143-A145 VanDerWaalsContact O-N 3.12Å
146N91.1Very high86.7Confident12 Ų1240.5 Ų40.56%0.06420%0.201CC..G310 helixtrans-102.22.2177.9-70.6-7.3000112.6D141 K143 P144 G158 D159D141-N146 VanDerWaalsContact CG-ND2 3.29Å; D141-N146 PolarHBondContact O-ND2 3.4Å; D141-N146 PolarHBondContact OD2-ND2 3.34Å; K143-N146 WeakPolarHBondContact CE-ND2 3.14Å; K143-N146 HydrophobicContact CG-CB 4.16Å; K143-N146 PolarHBondContact O-N 3.47Å; P144-N146 PolarHBondContact O-N 2.93Å; N146-G158 PolarHBondContact O-N 3.17Å; N146-D159 HydrophobicContact CB-CB 4.38Å
147I95.1Very high87.7Confident0 Ų036.9 Ų36.90%018%0.179CC..EExtended strand (participates in β ladder)trans-107.1115.9174.3-50.7-49.1000108.8D93 L94 L120 L142 P144 V155 L157 L205D93-I147 CarbonylContact C-O 3.59Å; D93-I147 VanDerWaalsContact CA-O 3.25Å; D93-I147 WeakPolarHBondContact CA-O 3.45Å; L94-I147 HydrophobicContact CB-CB 4.34Å; L94-I147 HydrophobicContact CD1-CB 3.61Å; L94-I147 HydrophobicContact CD1-CG1 4.16Å; L94-I147 HydrophobicContact CD1-CG2 3.43Å; L94-I147 VanDerWaalsContact CD1-CG2 3.43Å; L94-I147 HydrophobicContact CG-CB 3.81Å; L94-I147 HydrophobicContact CG-CG2 3.77Å; L94-I147 PolarHBondContact N-O 3.23Å; L120-I147 HydrophobicContact CD1-CD1 4.3Å; L120-I147 HydrophobicContact CD1-CG1 4.24Å; L120-I147 HydrophobicContact CD1-CG2 4.33Å; L120-I147 HydrophobicContact CD2-CD1 3.81Å; L120-I147 HydrophobicContact CD2-CG1 4.36Å; L120-I147 HydrophobicContact CD2-CG2 3.88Å; L142-I147 HydrophobicContact CD2-CD1 4.11Å; P144-I147 PolarHBondContact O-N 2.95Å; P144-I147 VanDerWaalsContact O-N 3.16Å; I147-V155 HydrophobicContact CG2-CB 3.9Å; I147-V155 HydrophobicContact CG2-CG1 3.95Å; I147-L157 HydrophobicContact CD1-CD1 3.25Å; I147-L157 HydrophobicContact CD1-CG 4.49Å; I147-L205 HydrophobicContact CD1-CD1 4.31Å; I147-L205 HydrophobicContact CG1-CD1 3.5Å
148F94.9Very high88.2Confident61 Ų6136.6 Ų36.627%0.26818%0.178SC..EExtended strand (participates in β ladder)trans-102.8156-175.3-57.7-82.7000112V68 C89 G92 D93 V155 K156V68-F148 HydrophobicContact CG2-CD2 3.7Å; V68-F148 HydrophobicContact CG2-CE2 4.37Å; V68-F148 HydrophobicContact CG2-CG 4.47Å; C89-F148 HydrophobicContact CB-CB 3.49Å; C89-F148 VanDerWaalsContact CB-CB 3.49Å; C89-F148 HydrophobicContact CB-CD1 4.48Å; C89-F148 HydrophobicContact CB-CG 4.21Å; G92-F148 CarbonylContact O-C 3.55Å; G92-F148 VanDerWaalsContact O-CA 3.29Å; G92-F148 WeakPolarHBondContact O-CA 3.43Å; D93-F148 HydrophobicContact CB-CD1 4.13Å; D93-F148 HydrophobicContact CB-CE1 4.25Å; F148-V155 CarbonylContact O-C 3.58Å; F148-V155 VanDerWaalsContact O-CA 3.28Å; F148-V155 WeakPolarHBondContact O-CA 3.41Å; F148-K156 PolarHBondContact N-O 3.36Å; F148-K156 PolarHBondContact O-N 2.85Å
149L94Very high88.1Confident8 Ų837.2 Ų37.24%0.04218%0.181CC..EExtended strand (participates in β ladder)trans-112.1136.2176.9-65.6169.8000110.5C89 G91 G92 L94 L97 F112 N154 V155C89-L149 CarbonylContact C-O 3.53Å; C89-L149 WeakPolarHBondContact CB-O 3.43Å; G91-L149 VanDerWaalsContact CA-O 3.23Å; G91-L149 WeakPolarHBondContact CA-O 3.28Å; G91-L149 PolarHBondContact N-O 3.17Å; G92-L149 PolarHBondContact O-N 3.1Å; L94-L149 HydrophobicContact CD2-CD1 4.02Å; L94-L149 HydrophobicContact CD2-CD2 4.01Å; L94-L149 HydrophobicContact CD2-CG 4.08Å; L97-L149 HydrophobicContact CD2-CD1 4.21Å; F112-L149 HydrophobicContact CZ-CD2 4.24Å; L149-N154 WeakPolarHBondContact CA-O 3.4Å; L149-V155 HydrophobicContact CD2-CG1 3.63Å
150D89.5Confident87.3Confident26 Ų2637.7 Ų37.714%0.13918%0.183CC..  trans-82.7177.5166.377.99.5000111.8K152 Q153 N154D150-K152 PolarHBondContact O-N 3.14Å; D150-K152 VanDerWaalsContact O-N 3.09Å; D150-K152 VanDerWaalsContact OD1-C 3.26Å; D150-K152 VanDerWaalsContact OD1-CA 3.29Å; D150-K152 WeakPolarHBondContact OD1-CA 3.41Å; D150-K152 WeakPolarHBondContact OD1-CB 3.35Å; D150-K152 PolarHBondContact OD1-N 3.31Å; D150-Q153 PolarHBondContact O-N 2.73Å; D150-Q153 PolarHBondContact OD1-N 3.12Å; D150-Q153 VanDerWaalsContact OD1-N 3.08Å; D150-N154 PolarHBondContact N-O 2.72Å; D150-N154 PolarHBondContact OD1-N 3.22Å; D150-N154 PolarHBondContact OD1-ND2 2.77Å; D150-N154 WeakPolarHBondContact OD2-CB 3.28Å; D150-N154 PolarHBondContact OD2-ND2 3.17Å
151I86.2Confident86Confident118 Ų11833.5 Ų33.561%0.60517%0.168SC*.THydrogen-bonded Turntrans-59-21.1178.462.1-179.8000114.3E90E90-I151 HydrophobicContact CB-CG2 3.73Å; E90-I151 HydrophobicContact CG-CG2 3.88Å; E90-I151 WeakPolarHBondContact OE2-CG2 3.44Å
152K85.3Confident84.9Confident144 Ų14432 Ų3263%0.62616%0.16SC*.THydrogen-bonded Turntrans-100.511.7179.4-52.2-170.6179.2-174.70111.4D150 N154D150-K152 PolarHBondContact O-N 3.14Å; D150-K152 VanDerWaalsContact O-N 3.09Å; D150-K152 VanDerWaalsContact OD1-C 3.26Å; D150-K152 VanDerWaalsContact OD1-CA 3.29Å; D150-K152 WeakPolarHBondContact OD1-CA 3.41Å; D150-K152 WeakPolarHBondContact OD1-CB 3.35Å; D150-K152 PolarHBondContact OD1-N 3.31Å; K152-N154 PolarHBondContact O-N 3.37Å
153Q82.8Confident82.9Confident108 Ų10832.5 Ų32.551%0.50516%0.164SC..  trans60.124.4-175.8-54.3-177-14.900114.4F112 D150F112-Q153 HydrophobicContact CE2-CB 4.26Å; D150-Q153 PolarHBondContact O-N 2.73Å; D150-Q153 PolarHBondContact OD1-N 3.12Å; D150-Q153 VanDerWaalsContact OD1-N 3.08Å
154N88.4Confident81Confident16 Ų1635.6 Ų35.69%0.08617%0.174CC..  trans-76141.3166.6-51.8-60.9000108.9Q119 L149 D150 K152Q119-N154 PolarHBondContact NE2-OD1 2.87Å; L149-N154 WeakPolarHBondContact CA-O 3.4Å; D150-N154 PolarHBondContact N-O 2.72Å; D150-N154 PolarHBondContact OD1-N 3.22Å; D150-N154 PolarHBondContact OD1-ND2 2.77Å; D150-N154 WeakPolarHBondContact OD2-CB 3.28Å; D150-N154 PolarHBondContact OD2-ND2 3.17Å; K152-N154 PolarHBondContact O-N 3.37Å
155V94.3Very high78.9Confident1 Ų135.6 Ų35.61%0.00617%0.174CC..EExtended strand (participates in β ladder)trans-83.6144177-66.80000112N66 V116 Q119 L120 I147 F148 L149N66-V155 WeakPolarHBondContact CA-O 3.42Å; N66-V155 WeakPolarHBondContact CB-O 3.45Å; N66-V155 PolarHBondContact ND2-O 3.27Å; N66-V155 VanDerWaalsContact ND2-O 3.13Å; V116-V155 HydrophobicContact CB-CG1 4.3Å; V116-V155 HydrophobicContact CG1-CG1 4.1Å; V116-V155 HydrophobicContact CG2-CG1 3.75Å; Q119-V155 HydrophobicContact CB-CG2 3.28Å; Q119-V155 HydrophobicContact CG-CG2 4.25Å; L120-V155 HydrophobicContact CD2-CB 4.37Å; L120-V155 HydrophobicContact CD2-CG2 4.06Å; L120-V155 HydrophobicContact CG-CG2 4.05Å; I147-V155 HydrophobicContact CG2-CB 3.9Å; I147-V155 HydrophobicContact CG2-CG1 3.95Å; F148-V155 CarbonylContact O-C 3.58Å; F148-V155 VanDerWaalsContact O-CA 3.28Å; F148-V155 WeakPolarHBondContact O-CA 3.41Å; L149-V155 HydrophobicContact CD2-CG1 3.63Å
156K94Very high76.8Confident13 Ų1334.5 Ų34.56%0.05716%0.162CC..EExtended strand (participates in β ladder)trans-130117.2174.2-71.2173.1172.1-750108.8P65 N66 V68 E87 C89 F148P65-K156 PolarHBondContact O-NZ 3.17Å; N66-K156 WeakPolarHBondContact O-CA 3.45Å; V68-K156 HydrophobicContact CG2-CB 3.8Å; E87-K156 VanDerWaalsContact CD-CE 3.44Å; E87-K156 WeakPolarHBondContact OE1-CE 3.25Å; E87-K156 IonicContact OE1-NZ 2.75Å; E87-K156 PolarHBondContact OE1-NZ 2.71Å; E87-K156 WeakPolarHBondContact OE2-CE 3.43Å; E87-K156 IonicContact OE2-NZ 3.49Å; E87-K156 PolarHBondContact OE2-NZ 3.41Å; C89-K156 VanDerWaalsContact SG-CD 3.58Å; F148-K156 PolarHBondContact N-O 3.36Å; F148-K156 PolarHBondContact O-N 2.85Å
157L92.8Very high74.5Confident0 Ų036.7 Ų36.70%017%0.174CC..EExtended strand (participates in β ladder)trans-69.3126.6171.6-176.453.8000109.1N66 I67 V68 L120 A123 L124 H139 L142 I147 F160N66-L157 WeakPolarHBondContact O-CB 3.34Å; N66-L157 PolarHBondContact O-N 3.24Å; I67-L157 CarbonylContact C-O 3.48Å; I67-L157 WeakPolarHBondContact CA-O 3.37Å; V68-L157 WeakPolarHBondContact CG2-O 3.28Å; V68-L157 PolarHBondContact N-O 3.3Å; L120-L157 HydrophobicContact CD2-CB 4.25Å; A123-L157 HydrophobicContact CB-CB 4.06Å; A123-L157 HydrophobicContact CB-CD2 3.98Å; L124-L157 HydrophobicContact CD2-CD2 4.03Å; H139-L157 VanDerWaalsContact NE2-CD1 3.34Å; H139-L157 WeakPolarHBondContact NE2-CD1 3.31Å; L142-L157 HydrophobicContact CD2-CD1 3.41Å; L142-L157 VanDerWaalsContact CD2-CD1 3.41Å; L142-L157 HydrophobicContact CD2-CD2 4.31Å; I147-L157 HydrophobicContact CD1-CD1 3.25Å; I147-L157 HydrophobicContact CD1-CG 4.49Å; L157-F160 HydrophobicContact CB-CE2 3.9Å; L157-F160 HydrophobicContact CB-CZ 3.95Å; L157-F160 HydrophobicContact CD2-CE1 3.81Å; L157-F160 HydrophobicContact CD2-CE2 4.04Å; L157-F160 HydrophobicContact CD2-CZ 3.28Å; L157-F160 HydrophobicContact CG-CE1 4.13Å; L157-F160 HydrophobicContact CG-CE2 3.56Å; L157-F160 HydrophobicContact CG-CZ 3.36Å; L157-F160 WeakPolarHBondContact O-CE2 3.33Å
158G87.9Confident72Confident2 Ų243 Ų432%0.02120%0.203CC..  trans-127.7176.5179.500000113.1H139 N146H139-G158 PolarHBondContact NE2-O 2.83Å; N146-G158 PolarHBondContact O-N 3.17Å
159D74.9Confident69.3Low43 Ų4345.8 Ų45.823%0.2322%0.221CC..  trans65.928.6178.3-142.517.6000116.5K37 N146 G161K37-D159 IonicContact NZ-OD1 3.75Å; K37-D159 PolarHBondContact NZ-OD1 2.85Å; K37-D159 IonicContact NZ-OD2 3.58Å; K37-D159 PolarHBondContact NZ-OD2 3.42Å; N146-D159 HydrophobicContact CB-CB 4.38Å; D159-G161 VanDerWaalsContact C-N 3.33Å; D159-G161 PolarHBondContact O-N 3.38Å
160F63.4Low66.7Low11 Ų1147.9 Ų47.95%0.04823%0.234CC..THydrogen-bonded Turntrans-56-32.4178.3-81.4-79.7000116.6L59 L62 I67 C127 H139 L157L59-F160 HydrophobicContact CD2-CB 3.35Å; L59-F160 HydrophobicContact CD2-CG 4.42Å; L62-F160 HydrophobicContact CD1-CB 4.33Å; L62-F160 HydrophobicContact CD1-CD1 3.92Å; L62-F160 HydrophobicContact CD1-CD2 4.41Å; L62-F160 HydrophobicContact CD1-CE1 4.29Å; L62-F160 HydrophobicContact CD1-CG 3.97Å; I67-F160 HydrophobicContact CB-CE2 3.99Å; I67-F160 HydrophobicContact CB-CZ 4.45Å; I67-F160 HydrophobicContact CD1-CE1 4.48Å; I67-F160 HydrophobicContact CD1-CE2 3.99Å; I67-F160 HydrophobicContact CD1-CZ 3.62Å; I67-F160 HydrophobicContact CG1-CE2 3.68Å; I67-F160 HydrophobicContact CG1-CZ 3.65Å; I67-F160 HydrophobicContact CG2-CD2 3.92Å; I67-F160 HydrophobicContact CG2-CE2 3.39Å; I67-F160 HydrophobicContact CG2-CZ 4.16Å; C127-F160 HydrophobicContact CB-CE1 4.34Å; C127-F160 WeakPolarHBondContact SG-CE1 3.5Å; C127-F160 VanDerWaalsContact SG-CZ 3.51Å; H139-F160 AromaticContact CD2-CD1 3.54Å; H139-F160 AromaticContact CD2-CE1 3.49Å; H139-F160 VanDerWaalsContact CD2-CE1 3.49Å; H139-F160 WeakPolarHBondContact CD2-CE1 3.34Å; L157-F160 HydrophobicContact CB-CE2 3.9Å; L157-F160 HydrophobicContact CB-CZ 3.95Å; L157-F160 HydrophobicContact CD2-CE1 3.81Å; L157-F160 HydrophobicContact CD2-CE2 4.04Å; L157-F160 HydrophobicContact CD2-CZ 3.28Å; L157-F160 HydrophobicContact CG-CE1 4.13Å; L157-F160 HydrophobicContact CG-CE2 3.56Å; L157-F160 HydrophobicContact CG-CZ 3.36Å; L157-F160 WeakPolarHBondContact O-CE2 3.33Å
161G52.5Low64.4Low2 Ų248.3 Ų48.32%0.02124%0.239CC..THydrogen-bonded Turntrans-126.922.4-151.800000116.2E55 D159E55-G161 WeakPolarHBondContact CB-O 3.23Å; D159-G161 VanDerWaalsContact C-N 3.33Å; D159-G161 PolarHBondContact O-N 3.38Å
162L54Low61.9Low7 Ų749.5 Ų49.54%0.03724%0.24CC..THydrogen-bonded Turntrans-127.7-18.8171.6-65.9171.1000112.5K37 L39 L52 I84 R164 L166K37-L162 HydrophobicContact CD-CD1 3.74Å; L39-L162 HydrophobicContact CD1-CD1 4.09Å; L39-L162 HydrophobicContact CD1-CD2 4.48Å; L39-L162 HydrophobicContact CD2-CD1 3.71Å; L39-L162 HydrophobicContact CD2-CD2 3.32Å; L39-L162 HydrophobicContact CD2-CG 4.12Å; L39-L162 HydrophobicContact CG-CD1 4.33Å; L52-L162 HydrophobicContact CD1-CD2 3.53Å; I84-L162 HydrophobicContact CD1-CD2 4.2Å; L162-R164 VanDerWaalsContact C-N 3.32Å; L162-R164 PolarHBondContact O-N 3.26Å; L162-L166 HydrophobicContact CB-CD1 3.69Å; L162-L166 HydrophobicContact CB-CG 4.39Å; L162-L166 VanDerWaalsContact O-CB 3.26Å; L162-L166 WeakPolarHBondContact O-CB 3.34Å; L162-L166 WeakPolarHBondContact O-CD1 3.37Å; L162-L166 WeakPolarHBondContact O-CG 3.45Å; L162-L166 PolarHBondContact O-N 3.27Å; L162-L166 VanDerWaalsContact O-N 3.16Å
163A47.6Very low59.5Low11 Ų1145.6 Ų45.69%0.09124%0.235CC..Hα-helixtrans-60.1-38.8-177.100000112.8D141 N167D141-A163 HydrophobicContact CB-CB 4.42Å; A163-N167 WeakPolarHBondContact O-CB 3.34Å; A163-N167 PolarHBondContact O-N 2.87Å; A163-N167 PolarHBondContact O-ND2 3.31Å; A163-N167 PolarHBondContact O-OD1 3.09Å
164R50.1Low57.5Low120 Ų12044.2 Ų44.245%0.45323%0.227SC..Hα-helixtrans-65.6-42.7-174.8-124.3171.662.8151.89.9114.2E55 L162E55-R164 WeakPolarHBondContact OE1-CB 3.23Å; E55-R164 WeakPolarHBondContact OE1-CD 3.49Å; E55-R164 IonicContact OE1-CZ 3.64Å; E55-R164 IonicContact OE1-NE 3.46Å; E55-R164 PolarHBondContact OE1-NE 3.18Å; E55-R164 IonicContact OE1-NH2 2.73Å; L162-R164 VanDerWaalsContact C-N 3.32Å; L162-R164 PolarHBondContact O-N 3.26Å
165I47.7Very low55.4Low3 Ų346.1 Ų46.12%0.01524%0.24CC..Hα-helixtrans-80.1-46.2-175.8-56.8165.3000109.8E48 M51 L52 E55 N167 H168E48-I165 HydrophobicContact CB-CG2 4.28Å; M51-I165 HydrophobicContact CB-CD1 3.84Å; M51-I165 HydrophobicContact CB-CG1 3.56Å; M51-I165 HydrophobicContact CB-CG2 4.36Å; M51-I165 HydrophobicContact CE-CG2 4.33Å; M51-I165 WeakPolarHBondContact O-CD1 3.32Å; L52-I165 HydrophobicContact CB-CD1 3.84Å; L52-I165 HydrophobicContact CD1-CD1 4.17Å; E55-I165 HydrophobicContact CB-CD1 4.04Å; E55-I165 HydrophobicContact CG-CD1 3.42Å; E55-I165 VanDerWaalsContact CG-CD1 3.42Å; E55-I165 HydrophobicContact CG-CG1 3.83Å; I165-N167 PolarHBondContact O-N 2.99Å; I165-H168 PolarHBondContact O-N 3.12Å; I165-H168 VanDerWaalsContact O-N 3.12Å
166L46Very low52.7Low19 Ų1954.2 Ų54.210%0.09928%0.275CS..Hα-helixtrans-64.8-23.3179.5-61176.1000111.1Y19 M44 L162 H168 T170Y19-L166 HydrophobicContact CD1-CB 4.44Å; Y19-L166 HydrophobicContact CD1-CD1 3.64Å; Y19-L166 HydrophobicContact CD1-CD2 3.43Å; Y19-L166 VanDerWaalsContact CD1-CD2 3.43Å; Y19-L166 HydrophobicContact CD1-CG 4.01Å; Y19-L166 HydrophobicContact CD2-CD1 3.71Å; Y19-L166 HydrophobicContact CE1-CB 3.87Å; Y19-L166 HydrophobicContact CE1-CD1 3.81Å; Y19-L166 HydrophobicContact CE1-CD2 3.63Å; Y19-L166 HydrophobicContact CE1-CG 3.96Å; Y19-L166 HydrophobicContact CE2-CD1 3.92Å; Y19-L166 HydrophobicContact CG-CD1 3.55Å; Y19-L166 HydrophobicContact CG-CD2 4.14Å; Y19-L166 HydrophobicContact CG-CG 4.41Å; M44-L166 HydrophobicContact CE-CD2 4.49Å; L162-L166 HydrophobicContact CB-CD1 3.69Å; L162-L166 HydrophobicContact CB-CG 4.39Å; L162-L166 VanDerWaalsContact O-CB 3.26Å; L162-L166 WeakPolarHBondContact O-CB 3.34Å; L162-L166 WeakPolarHBondContact O-CD1 3.37Å; L162-L166 WeakPolarHBondContact O-CG 3.45Å; L162-L166 PolarHBondContact O-N 3.27Å; L162-L166 VanDerWaalsContact O-N 3.16Å; L166-H168 VanDerWaalsContact C-N 3.35Å; L166-H168 PolarHBondContact O-N 3.47Å; L166-T170 WeakPolarHBondContact O-CB 3.43Å; L166-T170 PolarHBondContact O-N 3.26Å; L166-T170 PolarHBondContact O-OG1 3.08Å
167N42.3Very low50.4Low58 Ų5859.7 Ų59.731%0.3131%0.309SS..THydrogen-bonded Turntrans-77.3-11.8177-76.1-10.3000115A163 I165 S171A163-N167 WeakPolarHBondContact O-CB 3.34Å; A163-N167 PolarHBondContact O-N 2.87Å; A163-N167 PolarHBondContact O-ND2 3.31Å; A163-N167 PolarHBondContact O-OD1 3.09Å; I165-N167 PolarHBondContact O-N 2.99Å; N167-S171 WeakPolarHBondContact O-CB 3.41Å; N167-S171 PolarHBondContact O-OG 3.39Å
168H42.8Very low48.7Very low132 Ų13262 Ų6261%0.61133%0.333SS*.THydrogen-bonded Turntrans-70-37.8-174.9-132.1-75.4000112.5I165 L166I165-H168 PolarHBondContact O-N 3.12Å; I165-H168 VanDerWaalsContact O-N 3.12Å; L166-H168 VanDerWaalsContact C-N 3.35Å; L166-H168 PolarHBondContact O-N 3.47Å
169D39.3Very low47.6Very low120 Ų12064 Ų6464%0.64235%0.345SS*.THydrogen-bonded Turntrans-123.1-30.3175.7-72.7-25.4000114
170T39.4Very low47.9Very low51 Ų5163.9 Ų63.931%0.31335%0.347SS..SBendtrans-91.6-5.7-178.877.30000114.7Y19 L166 F172 A173 K174Y19-T170 HydrophobicContact CE1-CG2 4.29Å; Y19-T170 WeakPolarHBondContact CE1-OG1 3.42Å; Y19-T170 PolarHBondContact OH-OG1 2.66Å; L166-T170 WeakPolarHBondContact O-CB 3.43Å; L166-T170 PolarHBondContact O-N 3.26Å; L166-T170 PolarHBondContact O-OG1 3.08Å; T170-F172 PolarHBondContact O-N 2.99Å; T170-A173 PolarHBondContact O-N 3.15Å; T170-A173 VanDerWaalsContact O-N 3.08Å; T170-K174 PolarHBondContact O-N 2.96Å
171S39.9Very low49.1Very low36 Ų3666.7 Ų66.725%0.25236%0.357SS..Hα-helixtrans-62.8-30.3172.867.80000111.5N167 A173 K174 T175N167-S171 WeakPolarHBondContact O-CB 3.41Å; N167-S171 PolarHBondContact O-OG 3.39Å; S171-A173 VanDerWaalsContact C-N 3.32Å; S171-A173 PolarHBondContact O-N 2.97Å; S171-K174 PolarHBondContact O-N 2.98Å; S171-T175 VanDerWaalsContact O-CB 3.31Å; S171-T175 WeakPolarHBondContact O-CB 3.4Å; S171-T175 WeakPolarHBondContact O-CG2 3.38Å; S171-T175 PolarHBondContact O-N 2.91Å; S171-T175 PolarHBondContact O-OG1 3.41Å
172F35.3Very low51Low142 Ų14268.4 Ų68.462%0.62336%0.363SS*.Hα-helixtrans-64.4-35173.4-100.1-86.5000112.5T170 T175T170-F172 PolarHBondContact O-N 2.99Å; F172-T175 WeakPolarHBondContact CA-OG1 3.4Å; F172-T175 PolarHBondContact O-OG1 3.21Å
173A34.6Very low52.7Low62 Ų6270.3 Ų70.351%0.51237%0.373SS..Hα-helixtrans-81.4-38176.300000112.4T170 S171 F176 V177T170-A173 PolarHBondContact O-N 3.15Å; T170-A173 VanDerWaalsContact O-N 3.08Å; S171-A173 VanDerWaalsContact C-N 3.32Å; S171-A173 PolarHBondContact O-N 2.97Å; A173-F176 WeakPolarHBondContact O-CB 3.46Å; A173-F176 PolarHBondContact O-N 2.94Å; A173-V177 PolarHBondContact O-N 3.24Å
174K40Very low54.8Low79 Ų7969.8 Ų69.834%0.34337%0.368SS..Hα-helixtrans-69.2-34.8174.9-106.5-174.4175.6170.40113.3Y19 T170 S171 F176 V177Y19-K174 HydrophobicContact CE2-CD 4.39Å; Y19-K174 VanDerWaalsContact OH-CD 3.26Å; Y19-K174 WeakPolarHBondContact OH-CD 3.5Å; Y19-K174 WeakPolarHBondContact OH-CE 3.2Å; Y19-K174 PolarHBondContact OH-NZ 3.24Å; T170-K174 PolarHBondContact O-N 2.96Å; S171-K174 PolarHBondContact O-N 2.98Å; K174-F176 PolarHBondContact O-N 3.26Å; K174-V177 PolarHBondContact O-N 3.23Å
175T44.1Very low56.7Low57 Ų5764.4 Ų64.435%0.3535%0.349SS..THydrogen-bonded Turntrans-68.8-4.8168.644.10000112.3S171 F172 Q221S171-T175 VanDerWaalsContact O-CB 3.31Å; S171-T175 WeakPolarHBondContact O-CB 3.4Å; S171-T175 WeakPolarHBondContact O-CG2 3.38Å; S171-T175 PolarHBondContact O-N 2.91Å; S171-T175 PolarHBondContact O-OG1 3.41Å; F172-T175 WeakPolarHBondContact CA-OG1 3.4Å; F172-T175 PolarHBondContact O-OG1 3.21Å; T175-Q221 VanDerWaalsContact O-CD 3.27Å; T175-Q221 PolarHBondContact O-NE2 2.73Å; T175-Q221 PolarHBondContact O-OE1 3.46Å; T175-Q221 VanDerWaalsContact O-OE1 3.09Å
176F37.2Very low58.6Low171 Ų17164.8 Ų64.875%0.7535%0.351SS*.THydrogen-bonded Turntrans-100.3-16.8170-102.5-94.3000113.7A173 K174A173-F176 WeakPolarHBondContact O-CB 3.46Å; A173-F176 PolarHBondContact O-N 2.94Å; K174-F176 PolarHBondContact O-N 3.26Å
177V45.8Very low60.4Low127 Ų12766 Ų6677%0.7736%0.356SS*.SBendtrans-119.773.2-175-168.90000109.8A173 K174A173-V177 PolarHBondContact O-N 3.24Å; K174-V177 PolarHBondContact O-N 3.23Å
178G57.6Low62.4Low48 Ų4865.3 Ų65.350%0.49535%0.352SS..SBendtrans146.3160.3173.600000113.7Q221G178-Q221 PolarHBondContact O-NE2 2.88Å
179T64.7Low64.1Low44 Ų4463 Ų6327%0.2734%0.344SS..  trans-98.7111.9174.8-57.80000108.4Y181 L224T179-Y181 VanDerWaalsContact C-N 3.3Å; T179-Y181 VanDerWaalsContact CB-CZ 3.48Å; T179-Y181 HydrophobicContact CG2-CD1 3.8Å; T179-Y181 HydrophobicContact CG2-CD2 4.43Å; T179-Y181 HydrophobicContact CG2-CE1 3.28Å; T179-Y181 HydrophobicContact CG2-CE2 3.97Å; T179-Y181 HydrophobicContact CG2-CG 4.35Å; T179-Y181 WeakPolarHBondContact O-CD2 3.46Å; T179-Y181 WeakPolarHBondContact O-CE2 3.36Å; T179-Y181 PolarHBondContact O-N 3.44Å; T179-L224 HydrophobicContact CG2-CD2 3.58Å
180P81.9Confident65.8Low42 Ų4267.8 Ų67.827%0.27335%0.353SS..  trans-79.769.5-169.832.8-37.9000112.9Y182 M183 L224P180-Y182 PolarHBondContact O-N 2.86Å; P180-M183 HydrophobicContact CB-CB 4.15Å; P180-M183 HydrophobicContact CB-CE 3.96Å; P180-M183 HydrophobicContact CG-CE 4.38Å; P180-M183 WeakPolarHBondContact O-CB 3.24Å; P180-M183 PolarHBondContact O-N 3.48Å; P180-L224 HydrophobicContact CG-CD2 4.07Å
181Y88.9Confident67.6Low69 Ų6971.1 Ų71.127%0.27137%0.366SS..THydrogen-bonded Turntrans-58.6-20.7-171.9-62.6-66.6000116.1T179 P214 F216 T217 L224T179-Y181 VanDerWaalsContact C-N 3.3Å; T179-Y181 VanDerWaalsContact CB-CZ 3.48Å; T179-Y181 HydrophobicContact CG2-CD1 3.8Å; T179-Y181 HydrophobicContact CG2-CD2 4.43Å; T179-Y181 HydrophobicContact CG2-CE1 3.28Å; T179-Y181 HydrophobicContact CG2-CE2 3.97Å; T179-Y181 HydrophobicContact CG2-CG 4.35Å; T179-Y181 WeakPolarHBondContact O-CD2 3.46Å; T179-Y181 WeakPolarHBondContact O-CE2 3.36Å; T179-Y181 PolarHBondContact O-N 3.44Å; Y181-P214 HydrophobicContact CD1-CB 4.17Å; Y181-P214 HydrophobicContact CD1-CG 4.16Å; Y181-P214 HydrophobicContact CD2-CG 4.38Å; Y181-P214 HydrophobicContact CG-CB 4.2Å; Y181-P214 HydrophobicContact CG-CG 3.97Å; Y181-F216 VanDerWaalsContact CD1-O 3.28Å; Y181-F216 WeakPolarHBondContact CD1-O 3.49Å; Y181-T217 HydrophobicContact CE1-CG2 4.35Å; Y181-L224 HydrophobicContact CD1-CD1 4.47Å
182Y92.1Very high69.3Low38 Ų3874.1 Ų74.115%0.14939%0.388CS..THydrogen-bonded Turntrans-105.10.8-175.1-46-85.3000113.3L142 K143 P144 P180 S201 C204 E208L142-Y182 WeakPolarHBondContact O-CB 3.31Å; K143-Y182 HydrophobicContact CB-CD2 3.63Å; K143-Y182 HydrophobicContact CB-CE2 3.62Å; K143-Y182 HydrophobicContact CB-CG 4.23Å; P144-Y182 WeakPolarHBondContact CD-OH 3.5Å; P144-Y182 HydrophobicContact CG-CE1 4.18Å; P144-Y182 WeakPolarHBondContact CG-OH 3.49Å; P180-Y182 PolarHBondContact O-N 2.86Å; Y182-S201 PolarHBondContact O-OG 3Å; Y182-C204 HydrophobicContact CD1-CB 3.65Å; Y182-C204 HydrophobicContact CE1-CB 4.38Å; Y182-C204 HydrophobicContact CG-CB 4.49Å; Y182-E208 VanDerWaalsContact CE1-OE2 3.24Å; Y182-E208 WeakPolarHBondContact CE1-OE2 3.28Å; Y182-E208 VanDerWaalsContact CZ-OE2 3.24Å; Y182-E208 PolarHBondContact OH-OE1 3.39Å; Y182-E208 PolarHBondContact OH-OE2 3.35Å
183M89.7Confident71.3Confident47 Ų4769.3 Ų69.323%0.23237%0.365CS..  trans-70.9135-178-170.2176.1-74.100111P180 Q187 I188 W200P180-M183 HydrophobicContact CB-CB 4.15Å; P180-M183 HydrophobicContact CB-CE 3.96Å; P180-M183 HydrophobicContact CG-CE 4.38Å; P180-M183 WeakPolarHBondContact O-CB 3.24Å; P180-M183 PolarHBondContact O-N 3.48Å; M183-Q187 HydrophobicContact CG-CB 3.34Å; M183-Q187 HydrophobicContact CG-CG 4.24Å; M183-Q187 HydrophobicContact SD-CB 4.01Å; M183-I188 HydrophobicContact CB-CG1 4.4Å; M183-I188 HydrophobicContact CG-CG1 3.84Å; M183-I188 HydrophobicContact SD-CG1 3.7Å; M183-W200 PolarHBondContact O-NE1 3.21Å; M183-W200 VanDerWaalsContact O-NE1 3.08Å
184S90.8Very high73.6Confident0 Ų067.9 Ų67.90%035%0.349CS..  trans-79.6159.5-179.968.70000113.2E186 Q187 I188 W200S184-E186 VanDerWaalsContact C-N 3.27Å; S184-E186 VanDerWaalsContact CB-CD 3.45Å; S184-E186 WeakPolarHBondContact CB-OE1 3.27Å; S184-E186 WeakPolarHBondContact CB-OE2 3.5Å; S184-E186 PolarHBondContact O-N 3.08Å; S184-E186 WeakPolarHBondContact OG-CG 3.37Å; S184-E186 PolarHBondContact OG-OE1 2.71Å; S184-E186 PolarHBondContact OG-OE2 3.2Å; S184-Q187 WeakPolarHBondContact O-CB 3.41Å; S184-Q187 PolarHBondContact O-N 3.43Å; S184-Q187 VanDerWaalsContact O-N 3.07Å; S184-Q187 WeakPolarHBondContact OG-CG 3.02Å; S184-Q187 PolarHBondContact OG-OE1 3.38Å; S184-I188 WeakPolarHBondContact O-CG1 3.45Å; S184-I188 PolarHBondContact O-N 3.24Å; S184-W200 VanDerWaalsContact CA-CD1 3.43Å
185P91.6Very high75.9Confident8 Ų868 Ų685%0.05235%0.351CS..Hα-helixtrans-54.4-41.4178.1-26.133.2000113.2Q187 I188 N189 W200 I228 L254P185-Q187 PolarHBondContact O-N 2.89Å; P185-I188 PolarHBondContact O-N 3.05Å; P185-N189 WeakPolarHBondContact O-CB 3.29Å; P185-N189 VanDerWaalsContact O-CG 3.23Å; P185-N189 PolarHBondContact O-N 3.39Å; P185-N189 PolarHBondContact O-ND2 2.86Å; P185-W200 HydrophobicContact CG-CE3 4.17Å; P185-W200 HydrophobicContact CG-CH2 3.64Å; P185-W200 HydrophobicContact CG-CZ2 4.04Å; P185-W200 HydrophobicContact CG-CZ3 3.71Å; P185-I228 HydrophobicContact CB-CG2 4.32Å; P185-I228 HydrophobicContact CG-CG2 3.8Å; P185-L254 HydrophobicContact CG-CD2 3.91Å
186E87.1Confident78.2Confident10 Ų1066.6 Ų66.65%0.04734%0.34CS..Hα-helixtrans-66-35.6177.864.7-82.9-175.500112.4S184 N189 R190 M191 S197 R259S184-E186 VanDerWaalsContact C-N 3.27Å; S184-E186 VanDerWaalsContact CB-CD 3.45Å; S184-E186 WeakPolarHBondContact CB-OE1 3.27Å; S184-E186 WeakPolarHBondContact CB-OE2 3.5Å; S184-E186 PolarHBondContact O-N 3.08Å; S184-E186 WeakPolarHBondContact OG-CG 3.37Å; S184-E186 PolarHBondContact OG-OE1 2.71Å; S184-E186 PolarHBondContact OG-OE2 3.2Å; E186-N189 CarbonylContact O-C 3.49Å; E186-N189 PolarHBondContact O-N 2.78Å; E186-R190 PolarHBondContact O-N 2.89Å; E186-M191 HydrophobicContact CB-CB 4Å; E186-M191 HydrophobicContact CB-SD 4.32Å; E186-M191 WeakPolarHBondContact O-CB 3.16Å; E186-M191 PolarHBondContact O-N 2.92Å; E186-S197 WeakPolarHBondContact CG-OG 3.32Å; E186-S197 VanDerWaalsContact OE1-CA 3.25Å; E186-S197 WeakPolarHBondContact OE1-CA 3.42Å; E186-S197 VanDerWaalsContact OE1-CB 3.25Å; E186-S197 WeakPolarHBondContact OE1-CB 3.41Å; E186-S197 PolarHBondContact OE1-OG 2.84Å; E186-R259 IonicContact OE1-CZ 3.44Å; E186-R259 IonicContact OE1-NH1 2.74Å; E186-R259 PolarHBondContact OE1-NH1 3.15Å; E186-R259 IonicContact OE1-NH2 3.5Å; E186-R259 IonicContact OE2-CZ 3.7Å; E186-R259 IonicContact OE2-NH1 2.82Å; E186-R259 PolarHBondContact OE2-NH1 3.31Å; E186-R259 IonicContact OE2-NH2 3.33Å; E186-R259 PolarHBondContact OE2-NH2 3.4Å
187Q83.9Confident80.8Confident46 Ų4658.5 Ų58.522%0.21531%0.305CS..Hα-helixtrans-66.3-42173.3-74.7-178.5-8000112.2M183 S184 P185 N189 R190 Y193M183-Q187 HydrophobicContact CG-CB 3.34Å; M183-Q187 HydrophobicContact CG-CG 4.24Å; M183-Q187 HydrophobicContact SD-CB 4.01Å; S184-Q187 WeakPolarHBondContact O-CB 3.41Å; S184-Q187 PolarHBondContact O-N 3.43Å; S184-Q187 VanDerWaalsContact O-N 3.07Å; S184-Q187 WeakPolarHBondContact OG-CG 3.02Å; S184-Q187 PolarHBondContact OG-OE1 3.38Å; P185-Q187 PolarHBondContact O-N 2.89Å; Q187-N189 VanDerWaalsContact C-N 3.27Å; Q187-N189 PolarHBondContact O-N 3.14Å; Q187-R190 PolarHBondContact O-N 3.08Å; Q187-R190 VanDerWaalsContact O-N 3.1Å; Q187-Y193 VanDerWaalsContact CD-CD2 3.43Å; Q187-Y193 HydrophobicContact CG-CD2 3.53Å; Q187-Y193 HydrophobicContact CG-CE2 3.93Å; Q187-Y193 VanDerWaalsContact NE2-CE2 3.3Å
188I83Confident83.1Confident42 Ų4252.4 Ų52.422%0.21527%0.268CS..Hα-helixtrans-62.8-39.1177.3-66.8172.6000110.5M183 S184 P185 R190 A225 I228M183-I188 HydrophobicContact CB-CG1 4.4Å; M183-I188 HydrophobicContact CG-CG1 3.84Å; M183-I188 HydrophobicContact SD-CG1 3.7Å; S184-I188 WeakPolarHBondContact O-CG1 3.45Å; S184-I188 PolarHBondContact O-N 3.24Å; P185-I188 PolarHBondContact O-N 3.05Å; I188-R190 PolarHBondContact O-N 3.19Å; I188-A225 HydrophobicContact CD1-CB 4.48Å; I188-A225 HydrophobicContact CG2-CB 3.65Å; I188-I228 HydrophobicContact CD1-CB 3.68Å; I188-I228 HydrophobicContact CD1-CD1 3.43Å; I188-I228 VanDerWaalsContact CD1-CD1 3.43Å; I188-I228 HydrophobicContact CD1-CG1 4.13Å; I188-I228 HydrophobicContact CD1-CG2 3.49Å; I188-I228 VanDerWaalsContact CD1-CG2 3.49Å
189N78.9Confident84.9Confident84 Ų8450.2 Ų50.245%0.44925%0.245SC..THydrogen-bonded Turntrans-80.46.8178-64.4-26.4000113.5P185 E186 Q187 M191P185-N189 WeakPolarHBondContact O-CB 3.29Å; P185-N189 VanDerWaalsContact O-CG 3.23Å; P185-N189 PolarHBondContact O-N 3.39Å; P185-N189 PolarHBondContact O-ND2 2.86Å; E186-N189 CarbonylContact O-C 3.49Å; E186-N189 PolarHBondContact O-N 2.78Å; Q187-N189 VanDerWaalsContact C-N 3.27Å; Q187-N189 PolarHBondContact O-N 3.14Å; N189-M191 HydrophobicContact CB-CG 4.08Å; N189-M191 HydrophobicContact CB-SD 4.21Å; N189-M191 PolarHBondContact O-N 3.04Å
190R75.9Confident86.5Confident220 Ų22048.1 Ų48.183%0.8323%0.232SC*.THydrogen-bonded Turntrans57.130.5-178.8-52.8-178.3178.4-160.2-1.7113.9E186 Q187 I188E186-R190 PolarHBondContact O-N 2.89Å; Q187-R190 PolarHBondContact O-N 3.08Å; Q187-R190 VanDerWaalsContact O-N 3.1Å; I188-R190 PolarHBondContact O-N 3.19Å
191M76.8Confident87.2Confident121 Ų12146.3 Ų46.360%0.59622%0.22SC*.PPolyproline II helixtrans-83.8170.5172.7-60.8176.265.900110.5E186 N189 Y193E186-M191 HydrophobicContact CB-CB 4Å; E186-M191 HydrophobicContact CB-SD 4.32Å; E186-M191 WeakPolarHBondContact O-CB 3.16Å; E186-M191 PolarHBondContact O-N 2.92Å; N189-M191 HydrophobicContact CB-CG 4.08Å; N189-M191 HydrophobicContact CB-SD 4.21Å; N189-M191 PolarHBondContact O-N 3.04Å; M191-Y193 PolarHBondContact O-N 2.88Å
192S75.4Confident87.6Confident100 Ų10043 Ų4370%0.69921%0.207SC*.PPolyproline II helixtrans-65.6128.1179.751.90000112
193Y77.8Confident87.9Confident40 Ų4041.2 Ų41.216%0.15720%0.2CC..PPolyproline II helixtrans-68.6132.3172.5-166.7-77.5000110.5L138 R140 Q187 M191 D198L138-Y193 HydrophobicContact CB-CD1 3.98Å; L138-Y193 HydrophobicContact CB-CE1 3.84Å; L138-Y193 HydrophobicContact CD1-CD1 3.56Å; L138-Y193 HydrophobicContact CD1-CE1 4.24Å; L138-Y193 HydrophobicContact CD2-CD1 4.31Å; L138-Y193 HydrophobicContact CD2-CE1 4.27Å; L138-Y193 HydrophobicContact CG-CD1 4.13Å; L138-Y193 HydrophobicContact CG-CE1 4.32Å; R140-Y193 HydrophobicContact CB-CE2 4.48Å; R140-Y193 HydrophobicContact CG-CD1 4.13Å; R140-Y193 HydrophobicContact CG-CE1 3.92Å; R140-Y193 HydrophobicContact CG-CE2 4.38Å; R140-Y193 HydrophobicContact CG-CG 4.44Å; Q187-Y193 VanDerWaalsContact CD-CD2 3.43Å; Q187-Y193 HydrophobicContact CG-CD2 3.53Å; Q187-Y193 HydrophobicContact CG-CE2 3.93Å; Q187-Y193 VanDerWaalsContact NE2-CE2 3.3Å; M191-Y193 PolarHBondContact O-N 2.88Å; Y193-D198 PolarHBondContact OH-N 3.25Å; Y193-D198 PolarHBondContact OH-OD1 3.42Å
194N82.5Confident88.3Confident33 Ų3339 Ų3918%0.17619%0.189CC..  trans-131.1179.5176.864.821.9000111.4K196 S197 D256N194-K196 PolarHBondContact O-N 2.9Å; N194-K196 WeakPolarHBondContact OD1-CA 3.12Å; N194-K196 VanDerWaalsContact OD1-CB 3.28Å; N194-K196 WeakPolarHBondContact OD1-CB 3.49Å; N194-K196 PolarHBondContact OD1-N 3.49Å; N194-S197 PolarHBondContact N-OG 3.32Å; N194-S197 WeakPolarHBondContact O-CB 3.39Å; N194-S197 PolarHBondContact O-N 3.35Å; N194-S197 PolarHBondContact O-OG 2.85Å; N194-S197 PolarHBondContact OD1-N 3.12Å; N194-S197 PolarHBondContact OD1-OG 3.25Å; N194-D256 PolarHBondContact ND2-OD2 3.39Å
195E88.5Confident88.6Confident81 Ų8139 Ų3938%0.37919%0.189SC..Hα-helixtrans-59.7-27.5178.471.6-70.6165.900112.7L138 S197 D198 I199L138-E195 HydrophobicContact CD2-CB 4.23Å; E195-S197 VanDerWaalsContact C-N 3.31Å; E195-S197 PolarHBondContact O-N 3.45Å; E195-D198 WeakPolarHBondContact O-CB 3.44Å; E195-D198 PolarHBondContact O-N 3.12Å; E195-I199 PolarHBondContact O-N 3.01Å
196K93.2Very high88.9Confident28 Ų2838.6 Ų38.612%0.12219%0.187CC..Hα-helixtrans-74.7-20.7176.3-55.8-58.4-166.274.70112.7N194 D198 I199 W200 D256 R259N194-K196 PolarHBondContact O-N 2.9Å; N194-K196 WeakPolarHBondContact OD1-CA 3.12Å; N194-K196 VanDerWaalsContact OD1-CB 3.28Å; N194-K196 WeakPolarHBondContact OD1-CB 3.49Å; N194-K196 PolarHBondContact OD1-N 3.49Å; K196-D198 VanDerWaalsContact C-N 3.34Å; K196-I199 HydrophobicContact CD-CG1 4.41Å; K196-I199 PolarHBondContact O-N 3.47Å; K196-W200 PolarHBondContact O-N 3.29Å; K196-W200 VanDerWaalsContact O-N 3.08Å; K196-D256 HydrophobicContact CB-CB 3.88Å; K196-D256 HydrophobicContact CG-CB 4.49Å; K196-D256 WeakPolarHBondContact CG-O 3.29Å; K196-D256 PolarHBondContact NZ-O 2.93Å; K196-R259 HydrophobicContact CD-CB 4.46Å; K196-R259 PolarHBondContact NZ-O 3.22Å; K196-R259 WeakPolarHBondContact O-CD 3.4Å; K196-R259 PolarHBondContact O-NH1 3.35Å
197S91.4Very high89.5Confident0 Ų038.7 Ų38.70%019%0.187CC..Hα-helixtrans-67-36.2168.8-51.10000111.5E186 N194 E195 I199 W200 S201E186-S197 WeakPolarHBondContact CG-OG 3.32Å; E186-S197 VanDerWaalsContact OE1-CA 3.25Å; E186-S197 WeakPolarHBondContact OE1-CA 3.42Å; E186-S197 VanDerWaalsContact OE1-CB 3.25Å; E186-S197 WeakPolarHBondContact OE1-CB 3.41Å; E186-S197 PolarHBondContact OE1-OG 2.84Å; N194-S197 PolarHBondContact N-OG 3.32Å; N194-S197 WeakPolarHBondContact O-CB 3.39Å; N194-S197 PolarHBondContact O-N 3.35Å; N194-S197 PolarHBondContact O-OG 2.85Å; N194-S197 PolarHBondContact OD1-N 3.12Å; N194-S197 PolarHBondContact OD1-OG 3.25Å; E195-S197 VanDerWaalsContact C-N 3.31Å; E195-S197 PolarHBondContact O-N 3.45Å; S197-I199 VanDerWaalsContact C-N 3.34Å; S197-W200 PolarHBondContact O-N 2.96Å; S197-S201 PolarHBondContact O-N 3.49Å; S197-S201 VanDerWaalsContact O-N 3.14Å; S197-S201 PolarHBondContact O-OG 2.9Å
198D92.6Very high90.2Very high0 Ų037.6 Ų37.60%018%0.181CC..Hα-helixtrans-65.2-38.8171.5-77.4-42.6000110.5L124 H128 H139 R140 L142 Y193 E195 K196 W200 S201 L202L124-D198 HydrophobicContact CD1-CB 4.4Å; L124-D198 HydrophobicContact CD2-CB 4.29Å; H128-D198 IonicContact CD2-OD2 3.55Å; H128-D198 IonicContact CE1-OD2 2.64Å; H128-D198 IonicContact NE2-OD2 3.7Å; H128-D198 PolarHBondContact NE2-OD2 2.88Å; H139-D198 WeakPolarHBondContact CB-OD1 3.14Å; H139-D198 PolarHBondContact N-OD1 3.44Å; H139-D198 PolarHBondContact N-OD2 2.9Å; H139-D198 VanDerWaalsContact N-OD2 3.15Å; R140-D198 PolarHBondContact N-OD1 3.1Å; L142-D198 HydrophobicContact CD1-CB 4.02Å; L142-D198 WeakPolarHBondContact CD1-O 3.42Å; Y193-D198 PolarHBondContact OH-N 3.25Å; Y193-D198 PolarHBondContact OH-OD1 3.42Å; E195-D198 WeakPolarHBondContact O-CB 3.44Å; E195-D198 PolarHBondContact O-N 3.12Å; K196-D198 VanDerWaalsContact C-N 3.34Å; D198-W200 PolarHBondContact O-N 3.47Å; D198-S201 PolarHBondContact O-N 2.88Å; D198-L202 WeakPolarHBondContact O-CB 3.49Å; D198-L202 PolarHBondContact O-N 2.78Å
199I97.3Very high90.9Very high1 Ų135.6 Ų35.61%0.00517%0.171CC..Hα-helixtrans-62.8-41.6176.5-58.7-55.1000112.1E195 K196 S197 L202 G203 M251 R259 V262 I265E195-I199 PolarHBondContact O-N 3.01Å; K196-I199 HydrophobicContact CD-CG1 4.41Å; K196-I199 PolarHBondContact O-N 3.47Å; S197-I199 VanDerWaalsContact C-N 3.34Å; I199-L202 PolarHBondContact O-N 3.48Å; I199-G203 PolarHBondContact O-N 3.04Å; I199-M251 HydrophobicContact CG2-CB 4.15Å; I199-M251 HydrophobicContact CG2-CE 4.01Å; I199-M251 HydrophobicContact CG2-CG 3.99Å; I199-M251 WeakPolarHBondContact O-CE 3.27Å; I199-R259 HydrophobicContact CG2-CB 4.12Å; I199-V262 HydrophobicContact CD1-CG2 3.89Å; I199-I265 HydrophobicContact CD1-CD1 3.93Å; I199-I265 HydrophobicContact CG2-CD1 4.22Å
200W97.5Very high91.8Very high0 Ų031.6 Ų31.60%015%0.15CC..Hα-helixtrans-58.8-49.3173.2173.7-81.1000111.3M183 S184 P185 K196 S197 D198 L202 G203 C204 F216 I228 L252 N253 L254M183-W200 PolarHBondContact O-NE1 3.21Å; M183-W200 VanDerWaalsContact O-NE1 3.08Å; S184-W200 VanDerWaalsContact CA-CD1 3.43Å; P185-W200 HydrophobicContact CG-CE3 4.17Å; P185-W200 HydrophobicContact CG-CH2 3.64Å; P185-W200 HydrophobicContact CG-CZ2 4.04Å; P185-W200 HydrophobicContact CG-CZ3 3.71Å; K196-W200 PolarHBondContact O-N 3.29Å; K196-W200 VanDerWaalsContact O-N 3.08Å; S197-W200 PolarHBondContact O-N 2.96Å; D198-W200 PolarHBondContact O-N 3.47Å; W200-L202 VanDerWaalsContact C-N 3.31Å; W200-L202 PolarHBondContact O-N 2.5Å; W200-G203 WeakPolarHBondContact O-CA 3.36Å; W200-G203 PolarHBondContact O-N 3.16Å; W200-C204 PolarHBondContact O-N 3.47Å; W200-F216 AromaticContact CH2-CE2 3.78Å; W200-F216 HydrophobicContact CH2-CE2 3.78Å; W200-F216 AromaticContact CH2-CZ 3.84Å; W200-F216 HydrophobicContact CH2-CZ 3.84Å; W200-F216 HydrophobicContact CZ2-CD2 4.15Å; W200-F216 AromaticContact CZ2-CE2 3.36Å; W200-F216 HydrophobicContact CZ2-CE2 3.36Å; W200-F216 AromaticContact CZ2-CZ 3.91Å; W200-F216 HydrophobicContact CZ2-CZ 3.91Å; W200-I228 HydrophobicContact CH2-CG2 4.21Å; W200-I228 HydrophobicContact CZ2-CG2 3.75Å; W200-L252 HydrophobicContact CD2-CD2 4.13Å; W200-L252 HydrophobicContact CE3-CD2 4.35Å; W200-L252 VanDerWaalsContact CZ3-C 3.46Å; W200-L252 HydrophobicContact CZ3-CB 4.46Å; W200-L252 VanDerWaalsContact CZ3-O 3.24Å; W200-L252 WeakPolarHBondContact CZ3-O 3.18Å; W200-N253 WeakPolarHBondContact CZ3-O 3.39Å; W200-L254 HydrophobicContact CH2-CD2 4.43Å
201S95.9Very high92.9Very high4 Ų422.1 Ų22.13%0.02812%0.119CC..Hα-helixtrans-61.4-41.3-178.6-51.10000111.5Y182 S197 D198 G203 C204 L205Y182-S201 PolarHBondContact O-OG 3Å; S197-S201 PolarHBondContact O-N 3.49Å; S197-S201 VanDerWaalsContact O-N 3.14Å; S197-S201 PolarHBondContact O-OG 2.9Å; D198-S201 PolarHBondContact O-N 2.88Å; S201-G203 VanDerWaalsContact C-N 3.34Å; S201-C204 PolarHBondContact O-N 2.82Å; S201-L205 PolarHBondContact O-N 3.45Å
202L97.5Very high93.9Very high0 Ų017.5 Ų17.50%010%0.096CC..Hα-helixtrans-62.1-41.2172.5-17961.6000111.4L120 L124 L142 D198 I199 W200 L205 L206 M251L120-L202 HydrophobicContact CB-CD1 3.83Å; L120-L202 HydrophobicContact CD1-CD1 3.64Å; L120-L202 HydrophobicContact CG-CD1 4.4Å; L124-L202 HydrophobicContact CD1-CB 4.43Å; L124-L202 HydrophobicContact CD1-CD2 3.9Å; L142-L202 HydrophobicContact CD1-CB 4.31Å; D198-L202 WeakPolarHBondContact O-CB 3.49Å; D198-L202 PolarHBondContact O-N 2.78Å; I199-L202 PolarHBondContact O-N 3.48Å; W200-L202 VanDerWaalsContact C-N 3.31Å; W200-L202 PolarHBondContact O-N 2.5Å; L202-L205 PolarHBondContact O-N 3.45Å; L202-L206 HydrophobicContact CD1-CD1 3.96Å; L202-L206 HydrophobicContact CD1-CG 4.1Å; L202-L206 HydrophobicContact CD2-CD1 4.4Å; L202-L206 HydrophobicContact CG-CD1 3.74Å; L202-L206 HydrophobicContact CG-CG 4.34Å; L202-L206 WeakPolarHBondContact O-CB 3.43Å; L202-L206 WeakPolarHBondContact O-CD1 3.44Å; L202-L206 VanDerWaalsContact O-CG 3.25Å; L202-L206 WeakPolarHBondContact O-CG 3.25Å; L202-L206 PolarHBondContact O-N 3.32Å; L202-M251 HydrophobicContact CB-CE 3.83Å; L202-M251 HydrophobicContact CD2-CE 3.7Å; L202-M251 HydrophobicContact CG-CE 3.62Å
203G98.3Very high94.9Very high0 Ų015.2 Ų15.20%08%0.08CC..Hα-helixtrans-59.1-45.4174.600000112.4I199 W200 S201 L205 L206 Y207I199-G203 PolarHBondContact O-N 3.04Å; W200-G203 WeakPolarHBondContact O-CA 3.36Å; W200-G203 PolarHBondContact O-N 3.16Å; S201-G203 VanDerWaalsContact C-N 3.34Å; G203-L205 PolarHBondContact O-N 3.22Å; G203-L206 PolarHBondContact O-N 3.04Å; G203-Y207 VanDerWaalsContact O-CB 3.28Å; G203-Y207 WeakPolarHBondContact O-CB 3.4Å; G203-Y207 PolarHBondContact O-N 3.33Å
204C98.3Very high95.8Very high0 Ų014.1 Ų14.10%08%0.078CC..Hα-helixtrans-61-44.4175.6-74.20000111.8Y182 W200 S201 Y207 E208 P215 L252Y182-C204 HydrophobicContact CD1-CB 3.65Å; Y182-C204 HydrophobicContact CE1-CB 4.38Å; Y182-C204 HydrophobicContact CG-CB 4.49Å; W200-C204 PolarHBondContact O-N 3.47Å; S201-C204 PolarHBondContact O-N 2.82Å; C204-Y207 PolarHBondContact O-N 3.33Å; C204-E208 WeakPolarHBondContact O-CB 3.41Å; C204-E208 PolarHBondContact O-N 2.9Å; C204-P215 HydrophobicContact CB-CG 4.09Å; C204-P215 VanDerWaalsContact SG-CG 3.6Å; C204-L252 VanDerWaalsContact SG-CD2 3.57Å
205L97.8Very high96.5Very high0 Ų013.1 Ų13.10%07%0.074CC..Hα-helixtrans-61.8-48178.4-177.9153000111.8L94 L120 P144 I147 S201 L202 G203 E208 L209L94-L205 HydrophobicContact CD1-CD2 4.16Å; L120-L205 HydrophobicContact CD1-CD1 4.5Å; L120-L205 HydrophobicContact CD1-CD2 4Å; P144-L205 HydrophobicContact CG-CD1 4.45Å; P144-L205 HydrophobicContact CG-CG 4.29Å; I147-L205 HydrophobicContact CD1-CD1 4.31Å; I147-L205 HydrophobicContact CG1-CD1 3.5Å; S201-L205 PolarHBondContact O-N 3.45Å; L202-L205 PolarHBondContact O-N 3.45Å; G203-L205 PolarHBondContact O-N 3.22Å; L205-E208 PolarHBondContact O-N 3.39Å; L205-L209 HydrophobicContact CD2-CD1 3.81Å; L205-L209 HydrophobicContact CD2-CG 4.3Å; L205-L209 WeakPolarHBondContact O-CG 3.48Å; L205-L209 PolarHBondContact O-N 2.82Å
206L98.4Very high96.9Very high0 Ų09.4 Ų9.40%06%0.056CC..Hα-helixtrans-67.9-37.8-179.5-67.1163.8000111.7I113 V116 M117 L202 G203 E208 L209 C210 L248 M251I113-L206 HydrophobicContact CG2-CD2 4.26Å; V116-L206 HydrophobicContact CG1-CD2 4.27Å; M117-L206 HydrophobicContact CB-CD1 4.19Å; M117-L206 HydrophobicContact CB-CD2 3.83Å; M117-L206 HydrophobicContact CE-CD1 3.87Å; M117-L206 HydrophobicContact CE-CD2 4.39Å; M117-L206 HydrophobicContact CG-CD1 3.75Å; M117-L206 HydrophobicContact CG-CD2 4.34Å; M117-L206 HydrophobicContact SD-CD1 4.31Å; L202-L206 HydrophobicContact CD1-CD1 3.96Å; L202-L206 HydrophobicContact CD1-CG 4.1Å; L202-L206 HydrophobicContact CD2-CD1 4.4Å; L202-L206 HydrophobicContact CG-CD1 3.74Å; L202-L206 HydrophobicContact CG-CG 4.34Å; L202-L206 WeakPolarHBondContact O-CB 3.43Å; L202-L206 WeakPolarHBondContact O-CD1 3.44Å; L202-L206 VanDerWaalsContact O-CG 3.25Å; L202-L206 WeakPolarHBondContact O-CG 3.25Å; L202-L206 PolarHBondContact O-N 3.32Å; G203-L206 PolarHBondContact O-N 3.04Å; L206-E208 VanDerWaalsContact C-N 3.3Å; L206-E208 PolarHBondContact O-N 3.39Å; L206-L209 HydrophobicContact CD2-CD1 4.35Å; L206-L209 PolarHBondContact O-N 2.78Å; L206-C210 PolarHBondContact O-N 2.8Å; L206-C210 VanDerWaalsContact O-N 3.13Å; L206-C210 PolarHBondContact O-SG 2.73Å; L206-L248 HydrophobicContact CB-CD2 3.5Å; L206-L248 HydrophobicContact CD1-CD2 4.13Å; L206-L248 HydrophobicContact CG-CD2 4.49Å; L206-M251 HydrophobicContact CD1-CE 3.98Å; L206-M251 HydrophobicContact CD1-SD 4.15Å
207Y98.7Very high96.8Very high13 Ų1311 Ų115%0.0517%0.068CC..Hα-helixtrans-57.8-45.5171-178.9-78.3000111G203 C204 L209 C210 A211 S213 P215 F233 R234 I236 L252G203-Y207 VanDerWaalsContact O-CB 3.28Å; G203-Y207 WeakPolarHBondContact O-CB 3.4Å; G203-Y207 PolarHBondContact O-N 3.33Å; C204-Y207 PolarHBondContact O-N 3.33Å; Y207-L209 PolarHBondContact O-N 3.22Å; Y207-C210 WeakPolarHBondContact O-CA 3.37Å; Y207-C210 WeakPolarHBondContact O-CB 3.25Å; Y207-C210 PolarHBondContact O-N 2.84Å; Y207-A211 HydrophobicContact CD1-CB 4.05Å; Y207-A211 HydrophobicContact CE1-CB 3.57Å; Y207-A211 WeakPolarHBondContact O-CB 3.14Å; Y207-A211 PolarHBondContact O-N 2.83Å; Y207-S213 WeakPolarHBondContact CD1-O 3.37Å; Y207-S213 WeakPolarHBondContact CE1-O 3.37Å; Y207-P215 HydrophobicContact CD1-CB 3.69Å; Y207-P215 HydrophobicContact CD1-CG 4.12Å; Y207-P215 HydrophobicContact CD2-CB 4.15Å; Y207-P215 VanDerWaalsContact CE1-CA 3.42Å; Y207-P215 HydrophobicContact CE1-CB 3.88Å; Y207-P215 HydrophobicContact CE2-CB 4.31Å; Y207-P215 HydrophobicContact CG-CB 3.84Å; Y207-P215 HydrophobicContact CG-CG 4.23Å; Y207-F233 HydrophobicContact CD2-CD2 4.18Å; Y207-F233 HydrophobicContact CD2-CE2 4.44Å; Y207-F233 AromaticContact CE2-CD2 3.73Å; Y207-F233 HydrophobicContact CE2-CD2 3.73Å; Y207-F233 HydrophobicContact CE2-CE2 4.31Å; Y207-R234 VanDerWaalsContact CE2-O 3.22Å; Y207-R234 WeakPolarHBondContact CE2-O 3.34Å; Y207-R234 PolarHBondContact OH-O 3.32Å; Y207-I236 HydrophobicContact CD2-CG2 3.53Å; Y207-I236 HydrophobicContact CE2-CG2 3.63Å; Y207-I236 HydrophobicContact CG-CG2 4.27Å; Y207-L252 HydrophobicContact CD2-CD1 4.37Å
208E98.4Very high96.8Very high22 Ų2211.7 Ų11.710%0.1037%0.074CC..Hα-helixtrans-65.7-36.5179.4-171.6179.8-172.500112.5I98 P144 Y182 C204 L205 L206 C210 A211 L212 P214I98-E208 HydrophobicContact CD1-CG 3.93Å; P144-E208 VanDerWaalsContact CG-OE2 3.31Å; P144-E208 WeakPolarHBondContact CG-OE2 3.28Å; Y182-E208 VanDerWaalsContact CE1-OE2 3.24Å; Y182-E208 WeakPolarHBondContact CE1-OE2 3.28Å; Y182-E208 VanDerWaalsContact CZ-OE2 3.24Å; Y182-E208 PolarHBondContact OH-OE1 3.39Å; Y182-E208 PolarHBondContact OH-OE2 3.35Å; C204-E208 WeakPolarHBondContact O-CB 3.41Å; C204-E208 PolarHBondContact O-N 2.9Å; L205-E208 PolarHBondContact O-N 3.39Å; L206-E208 VanDerWaalsContact C-N 3.3Å; L206-E208 PolarHBondContact O-N 3.39Å; E208-C210 PolarHBondContact O-N 2.82Å; E208-A211 PolarHBondContact O-N 2.95Å; E208-L212 WeakPolarHBondContact O-CA 3.42Å; E208-L212 PolarHBondContact O-N 2.86Å; E208-P214 HydrophobicContact CG-CG 4.44Å
209L98.3Very high96.4Very high0 Ų022.4 Ų22.40%012%0.116CC..Hα-helixtrans-60.9-34.6170.9-67.4174.5000112.1L94 I98 L108 I113 V116 L205 L206 Y207L94-L209 HydrophobicContact CD1-CD1 4.22Å; L94-L209 HydrophobicContact CD1-CD2 4.31Å; L94-L209 HydrophobicContact CD2-CD2 4.47Å; I98-L209 HydrophobicContact CD1-CD2 3.9Å; I98-L209 HydrophobicContact CG1-CD2 3.85Å; L108-L209 HydrophobicContact CD1-CB 4.1Å; L108-L209 HydrophobicContact CD1-CD2 3.67Å; L108-L209 HydrophobicContact CD1-CG 4.46Å; I113-L209 HydrophobicContact CD1-CB 4.42Å; I113-L209 HydrophobicContact CG1-CB 4.27Å; V116-L209 HydrophobicContact CB-CD1 4.28Å; V116-L209 HydrophobicContact CG1-CD1 3.79Å; V116-L209 HydrophobicContact CG2-CD1 4.42Å; L205-L209 HydrophobicContact CD2-CD1 3.81Å; L205-L209 HydrophobicContact CD2-CG 4.3Å; L205-L209 WeakPolarHBondContact O-CG 3.48Å; L205-L209 PolarHBondContact O-N 2.82Å; L206-L209 HydrophobicContact CD2-CD1 4.35Å; L206-L209 PolarHBondContact O-N 2.78Å; Y207-L209 PolarHBondContact O-N 3.22Å
210C98.6Very high95.9Very high0 Ų026.1 Ų26.10%014%0.135CC..Hα-helixtrans-73.2-53.1176.9-61.40000111.7Y107 I113 L206 Y207 E208 I236 Y240Y107-C210 WeakPolarHBondContact CD1-O 3.3Å; Y107-C210 WeakPolarHBondContact CE1-O 3.48Å; I113-C210 HydrophobicContact CD1-CB 4.44Å; L206-C210 PolarHBondContact O-N 2.8Å; L206-C210 VanDerWaalsContact O-N 3.13Å; L206-C210 PolarHBondContact O-SG 2.73Å; Y207-C210 WeakPolarHBondContact O-CA 3.37Å; Y207-C210 WeakPolarHBondContact O-CB 3.25Å; Y207-C210 PolarHBondContact O-N 2.84Å; E208-C210 PolarHBondContact O-N 2.82Å; C210-I236 HydrophobicContact CB-CB 3.98Å; C210-I236 HydrophobicContact CB-CD1 4.49Å; C210-I236 HydrophobicContact CB-CG2 3.77Å; C210-Y240 WeakPolarHBondContact CA-OH 3.44Å; C210-Y240 HydrophobicContact CB-CD2 3.96Å; C210-Y240 HydrophobicContact CB-CE2 3.63Å; C210-Y240 WeakPolarHBondContact O-CE2 3.4Å; C210-Y240 PolarHBondContact O-OH 3.24Å
211A98.1Very high95.3Very high21 Ų2129.6 Ų29.617%0.17415%0.152CC..Hα-helixtrans-92.1-10.6-168.400000114.2Y207 E208 S213Y207-A211 HydrophobicContact CD1-CB 4.05Å; Y207-A211 HydrophobicContact CE1-CB 3.57Å; Y207-A211 WeakPolarHBondContact O-CB 3.14Å; Y207-A211 PolarHBondContact O-N 2.83Å; E208-A211 PolarHBondContact O-N 2.95Å; A211-S213 PolarHBondContact O-N 3.26Å
212L97.6Very high94.9Very high24 Ų2436.5 Ų36.513%0.12618%0.181CC..SBendtrans55.824.9-169.6-53.4178.8000113.2I98 C101 I102 Y107 E208I98-L212 HydrophobicContact CG2-CD2 4.27Å; C101-L212 HydrophobicContact CB-CD1 4.05Å; C101-L212 HydrophobicContact CB-CD2 3.78Å; I102-L212 HydrophobicContact CD1-CB 4.32Å; I102-L212 WeakPolarHBondContact CD1-O 3.41Å; I102-L212 HydrophobicContact CG1-CB 3.75Å; I102-L212 HydrophobicContact CG1-CD1 4.16Å; I102-L212 HydrophobicContact CG1-CG 4.44Å; Y107-L212 HydrophobicContact CD1-CD1 3.88Å; Y107-L212 HydrophobicContact CD1-CG 3.89Å; Y107-L212 HydrophobicContact CE1-CD1 4.1Å; Y107-L212 HydrophobicContact CE1-CG 4.07Å; E208-L212 WeakPolarHBondContact O-CA 3.42Å; E208-L212 PolarHBondContact O-N 2.86Å
213S96.4Very high94.6Very high52 Ų5238.8 Ų38.836%0.36419%0.192SC..SBendtrans-158.3141.4178.3-178.10000108.9Y207 A211Y207-S213 WeakPolarHBondContact CD1-O 3.37Å; Y207-S213 WeakPolarHBondContact CE1-O 3.37Å; A211-S213 PolarHBondContact O-N 3.26Å
214P96.6Very high94.3Very high18 Ų1838.9 Ų38.912%0.11719%0.193CC..  trans-58.3155.3176.5-2433.4000113Y181 E208 F216 T217Y181-P214 HydrophobicContact CD1-CB 4.17Å; Y181-P214 HydrophobicContact CD1-CG 4.16Å; Y181-P214 HydrophobicContact CD2-CG 4.38Å; Y181-P214 HydrophobicContact CG-CB 4.2Å; Y181-P214 HydrophobicContact CG-CG 3.97Å; E208-P214 HydrophobicContact CG-CG 4.44Å; P214-F216 VanDerWaalsContact C-N 3.29Å; P214-F216 PolarHBondContact O-N 3.22Å; P214-T217 HydrophobicContact CB-CG2 4.21Å; P214-T217 HydrophobicContact CG-CG2 4.42Å
215P97.3Very high93.9Very high12 Ų1239.8 Ų39.88%0.07820%0.2CC..SBendtrans-65.7-32.118024.3-32000113.1C204 Y207 F233 L252C204-P215 HydrophobicContact CB-CG 4.09Å; C204-P215 VanDerWaalsContact SG-CG 3.6Å; Y207-P215 HydrophobicContact CD1-CB 3.69Å; Y207-P215 HydrophobicContact CD1-CG 4.12Å; Y207-P215 HydrophobicContact CD2-CB 4.15Å; Y207-P215 VanDerWaalsContact CE1-CA 3.42Å; Y207-P215 HydrophobicContact CE1-CB 3.88Å; Y207-P215 HydrophobicContact CE2-CB 4.31Å; Y207-P215 HydrophobicContact CG-CB 3.84Å; Y207-P215 HydrophobicContact CG-CG 4.23Å; P215-F233 HydrophobicContact CB-CB 3.91Å; P215-F233 HydrophobicContact CB-CD2 4.45Å; P215-F233 HydrophobicContact CB-CG 4.16Å; P215-F233 WeakPolarHBondContact O-CB 3.31Å; P215-L252 HydrophobicContact CB-CD1 4.06Å; P215-L252 HydrophobicContact CG-CD1 4.12Å
216F96.3Very high93.7Very high3 Ų343.4 Ų43.41%0.01322%0.217CC..SBendtrans-120.9119.6178.7-48.9-78000108.9Y181 W200 P214 L224 K227 I228 F233Y181-F216 VanDerWaalsContact CD1-O 3.28Å; Y181-F216 WeakPolarHBondContact CD1-O 3.49Å; W200-F216 AromaticContact CH2-CE2 3.78Å; W200-F216 HydrophobicContact CH2-CE2 3.78Å; W200-F216 AromaticContact CH2-CZ 3.84Å; W200-F216 HydrophobicContact CH2-CZ 3.84Å; W200-F216 HydrophobicContact CZ2-CD2 4.15Å; W200-F216 AromaticContact CZ2-CE2 3.36Å; W200-F216 HydrophobicContact CZ2-CE2 3.36Å; W200-F216 AromaticContact CZ2-CZ 3.91Å; W200-F216 HydrophobicContact CZ2-CZ 3.91Å; P214-F216 VanDerWaalsContact C-N 3.29Å; P214-F216 PolarHBondContact O-N 3.22Å; F216-L224 HydrophobicContact CB-CD1 3.73Å; F216-L224 WeakPolarHBondContact O-CD1 3.48Å; F216-K227 HydrophobicContact CD1-CB 4.32Å; F216-I228 HydrophobicContact CB-CG1 3.87Å; F216-I228 HydrophobicContact CD1-CG1 4.3Å; F216-I228 HydrophobicContact CD2-CG1 3.82Å; F216-I228 HydrophobicContact CE2-CG1 4.48Å; F216-I228 HydrophobicContact CG-CG1 3.72Å; F216-F233 HydrophobicContact CE1-CB 4.1Å; F216-F233 AromaticContact CE1-CD1 3.92Å; F216-F233 HydrophobicContact CE1-CD1 3.92Å; F216-F233 HydrophobicContact CE1-CG 4.48Å; F216-F233 HydrophobicContact CZ-CB 4.39Å; F216-F233 AromaticContact CZ-CD1 3.63Å; F216-F233 HydrophobicContact CZ-CD1 3.63Å; F216-F233 HydrophobicContact CZ-CE1 4.37Å; F216-F233 HydrophobicContact CZ-CG 4.36Å
217T92.8Very high93.5Very high62 Ų6246.8 Ų46.838%0.3823%0.231SC..  trans-128.1144177.557.90000110.2Y181 P214 K227Y181-T217 HydrophobicContact CE1-CG2 4.35Å; P214-T217 HydrophobicContact CB-CG2 4.21Å; P214-T217 HydrophobicContact CG-CG2 4.42Å; T217-K227 WeakPolarHBondContact O-CD 3.48Å; T217-K227 WeakPolarHBondContact O-CE 3.19Å; T217-K227 PolarHBondContact O-NZ 3.39Å
218A90.4Very high93.3Very high13 Ų1346.1 Ų46.111%0.10723%0.229CC..  trans-157.9163.5-17900000110.4E223 L224 K227A218-E223 HydrophobicContact CB-CB 3.86Å; A218-E223 HydrophobicContact CB-CG 3.8Å; A218-L224 HydrophobicContact CB-CB 3.82Å; A218-L224 HydrophobicContact CB-CD1 4.49Å; A218-L224 VanDerWaalsContact CB-N 3.31Å; A218-K227 HydrophobicContact CB-CD 4.45Å
219Y85.1Confident93Very high225 Ų22551 Ų5188%0.88225%0.246SC*.SBendtrans-84.2-20.4178.1-64.2-76.4000113E223Y219-E223 PolarHBondContact N-OE2 3.27Å; Y219-E223 VanDerWaalsContact N-OE2 3.1Å
220N85.9Confident92.9Very high79 Ų7956.6 Ų56.642%0.42227%0.272SS..SBendtrans-143.7165.3178.266.674.6000111K222 E223 L224N220-K222 PolarHBondContact O-N 3.3Å; N220-K222 WeakPolarHBondContact OD1-CB 3.17Å; N220-K222 PolarHBondContact OD1-N 3.33Å; N220-K222 VanDerWaalsContact OD1-N 3.12Å; N220-E223 PolarHBondContact O-N 2.96Å; N220-E223 PolarHBondContact OD1-N 3.32Å; N220-L224 PolarHBondContact O-N 3.15Å
221Q84.3Confident92.6Very high73 Ų7357.5 Ų57.534%0.34128%0.282SS..Hα-helixtrans-69-31.8-174.3-66.5-179.3-7.500113.9T175 G178 L224 A225T175-Q221 VanDerWaalsContact O-CD 3.27Å; T175-Q221 PolarHBondContact O-NE2 2.73Å; T175-Q221 PolarHBondContact O-OE1 3.46Å; T175-Q221 VanDerWaalsContact O-OE1 3.09Å; G178-Q221 PolarHBondContact O-NE2 2.88Å; Q221-L224 PolarHBondContact O-N 3.34Å; Q221-A225 VanDerWaalsContact O-CB 3.31Å; Q221-A225 WeakPolarHBondContact O-CB 3.26Å; Q221-A225 PolarHBondContact O-N 2.72Å
222K87.8Confident92.5Very high150 Ų15064.1 Ų64.165%0.65231%0.307SS*.Hα-helixtrans-65.7-47.9178.1-175.7-175.1173.9-172.10110.4N220 L224 A225 E226N220-K222 PolarHBondContact O-N 3.3Å; N220-K222 WeakPolarHBondContact OD1-CB 3.17Å; N220-K222 PolarHBondContact OD1-N 3.33Å; N220-K222 VanDerWaalsContact OD1-N 3.12Å; K222-L224 VanDerWaalsContact C-N 3.33Å; K222-L224 PolarHBondContact O-N 3.49Å; K222-A225 WeakPolarHBondContact O-CB 3.38Å; K222-A225 PolarHBondContact O-N 3.01Å; K222-E226 WeakPolarHBondContact CE-OE1 3.42Å; K222-E226 WeakPolarHBondContact O-CG 3.47Å; K222-E226 PolarHBondContact O-N 3.48Å
223E91.4Very high92.5Very high48 Ų4865.9 Ų65.922%0.22431%0.313CS..Hα-helixtrans-63.5-39.6176-175-158.7162.300111A218 Y219 N220 A225 E226 K227A218-E223 HydrophobicContact CB-CB 3.86Å; A218-E223 HydrophobicContact CB-CG 3.8Å; Y219-E223 PolarHBondContact N-OE2 3.27Å; Y219-E223 VanDerWaalsContact N-OE2 3.1Å; N220-E223 PolarHBondContact O-N 2.96Å; N220-E223 PolarHBondContact OD1-N 3.32Å; E223-A225 VanDerWaalsContact C-N 3.34Å; E223-A225 PolarHBondContact O-N 3.21Å; E223-E226 PolarHBondContact O-N 3.02Å; E223-K227 PolarHBondContact O-N 3.25Å; E223-K227 IonicContact OE1-NZ 3.9Å; E223-K227 PolarHBondContact OE1-NZ 3.3Å
224L91.7Very high92.5Very high2 Ų273.6 Ų73.61%0.0133%0.334CS..Hα-helixtrans-59.9-46.6173.5-178.161.9000111.1T179 P180 Y181 F216 A218 N220 Q221 K222 E226 K227 I228T179-L224 HydrophobicContact CG2-CD2 3.58Å; P180-L224 HydrophobicContact CG-CD2 4.07Å; Y181-L224 HydrophobicContact CD1-CD1 4.47Å; F216-L224 HydrophobicContact CB-CD1 3.73Å; F216-L224 WeakPolarHBondContact O-CD1 3.48Å; A218-L224 HydrophobicContact CB-CB 3.82Å; A218-L224 HydrophobicContact CB-CD1 4.49Å; A218-L224 VanDerWaalsContact CB-N 3.31Å; N220-L224 PolarHBondContact O-N 3.15Å; Q221-L224 PolarHBondContact O-N 3.34Å; K222-L224 VanDerWaalsContact C-N 3.33Å; K222-L224 PolarHBondContact O-N 3.49Å; L224-E226 VanDerWaalsContact C-N 3.28Å; L224-E226 PolarHBondContact O-N 3.05Å; L224-K227 PolarHBondContact O-N 3.01Å; L224-I228 HydrophobicContact CD1-CD1 3.89Å; L224-I228 HydrophobicContact CD1-CG1 4.22Å; L224-I228 HydrophobicContact CD2-CD1 4.22Å; L224-I228 HydrophobicContact CG-CD1 3.71Å; L224-I228 HydrophobicContact CG-CG1 4.39Å; L224-I228 WeakPolarHBondContact O-CG1 3.49Å; L224-I228 PolarHBondContact O-N 2.9Å
225A90.7Very high92.6Very high18 Ų1875.9 Ų75.915%0.14934%0.341CS..Hα-helixtrans-64.3-31.8179.300000112.8I188 Q221 K222 E223 R229I188-A225 HydrophobicContact CD1-CB 4.48Å; I188-A225 HydrophobicContact CG2-CB 3.65Å; Q221-A225 VanDerWaalsContact O-CB 3.31Å; Q221-A225 WeakPolarHBondContact O-CB 3.26Å; Q221-A225 PolarHBondContact O-N 2.72Å; K222-A225 WeakPolarHBondContact O-CB 3.38Å; K222-A225 PolarHBondContact O-N 3.01Å; E223-A225 VanDerWaalsContact C-N 3.34Å; E223-A225 PolarHBondContact O-N 3.21Å; A225-R229 WeakPolarHBondContact O-CB 3.12Å; A225-R229 VanDerWaalsContact O-CG 3.3Å; A225-R229 WeakPolarHBondContact O-CG 3.45Å; A225-R229 PolarHBondContact O-N 3.1Å; A225-R229 VanDerWaalsContact O-N 3.11Å; A225-R229 PolarHBondContact O-NE 3.32Å
226E92.9Very high92.6Very high77 Ų7775.4 Ų75.436%0.3634%0.337SS..Hα-helixtrans-66.3-50.5171.6-72.8169.1-177.200110.9K222 E223 L224 I228 R229 E230K222-E226 WeakPolarHBondContact CE-OE1 3.42Å; K222-E226 WeakPolarHBondContact O-CG 3.47Å; K222-E226 PolarHBondContact O-N 3.48Å; E223-E226 PolarHBondContact O-N 3.02Å; L224-E226 VanDerWaalsContact C-N 3.28Å; L224-E226 PolarHBondContact O-N 3.05Å; E226-I228 VanDerWaalsContact C-N 3.33Å; E226-I228 PolarHBondContact O-N 2.69Å; E226-R229 PolarHBondContact O-N 2.73Å; E226-R229 VanDerWaalsContact O-N 3.11Å; E226-E230 PolarHBondContact O-N 3.36Å
227K94.6Very high92.7Very high70 Ų7076.6 Ų76.630%0.30435%0.346SS..Hα-helixtrans-59.1-41.4177.3-77173.3169.2163.10113.1F216 T217 A218 E223 L224 E230 G231F216-K227 HydrophobicContact CD1-CB 4.32Å; T217-K227 WeakPolarHBondContact O-CD 3.48Å; T217-K227 WeakPolarHBondContact O-CE 3.19Å; T217-K227 PolarHBondContact O-NZ 3.39Å; A218-K227 HydrophobicContact CB-CD 4.45Å; E223-K227 PolarHBondContact O-N 3.25Å; E223-K227 IonicContact OE1-NZ 3.9Å; E223-K227 PolarHBondContact OE1-NZ 3.3Å; L224-K227 PolarHBondContact O-N 3.01Å; K227-E230 PolarHBondContact O-N 3.26Å; K227-G231 PolarHBondContact O-N 2.8Å; K227-G231 VanDerWaalsContact O-N 3.12Å
228I94.6Very high93Very high0 Ų081.8 Ų81.80%036%0.363CS..Hα-helixtrans-66.5-39.5177-68.6170.2000110.8P185 I188 W200 F216 L224 E226 E230 G231 L254P185-I228 HydrophobicContact CB-CG2 4.32Å; P185-I228 HydrophobicContact CG-CG2 3.8Å; I188-I228 HydrophobicContact CD1-CB 3.68Å; I188-I228 HydrophobicContact CD1-CD1 3.43Å; I188-I228 VanDerWaalsContact CD1-CD1 3.43Å; I188-I228 HydrophobicContact CD1-CG1 4.13Å; I188-I228 HydrophobicContact CD1-CG2 3.49Å; I188-I228 VanDerWaalsContact CD1-CG2 3.49Å; W200-I228 HydrophobicContact CH2-CG2 4.21Å; W200-I228 HydrophobicContact CZ2-CG2 3.75Å; F216-I228 HydrophobicContact CB-CG1 3.87Å; F216-I228 HydrophobicContact CD1-CG1 4.3Å; F216-I228 HydrophobicContact CD2-CG1 3.82Å; F216-I228 HydrophobicContact CE2-CG1 4.48Å; F216-I228 HydrophobicContact CG-CG1 3.72Å; L224-I228 HydrophobicContact CD1-CD1 3.89Å; L224-I228 HydrophobicContact CD1-CG1 4.22Å; L224-I228 HydrophobicContact CD2-CD1 4.22Å; L224-I228 HydrophobicContact CG-CD1 3.71Å; L224-I228 HydrophobicContact CG-CG1 4.39Å; L224-I228 WeakPolarHBondContact O-CG1 3.49Å; L224-I228 PolarHBondContact O-N 2.9Å; E226-I228 VanDerWaalsContact C-N 3.33Å; E226-I228 PolarHBondContact O-N 2.69Å; I228-E230 VanDerWaalsContact C-N 3.33Å; I228-E230 PolarHBondContact O-N 3.37Å; I228-G231 PolarHBondContact O-N 2.61Å; I228-L254 WeakPolarHBondContact O-CD2 3.44Å
229R92Very high93.3Very high124 Ų12487.1 Ų87.147%0.46838%0.381SS..Hα-helixtrans-66.5-33.1175.3-80.8179.6-71.8145.1-8.1113.1A225 E226 G231 L254A225-R229 WeakPolarHBondContact O-CB 3.12Å; A225-R229 VanDerWaalsContact O-CG 3.3Å; A225-R229 WeakPolarHBondContact O-CG 3.45Å; A225-R229 PolarHBondContact O-N 3.1Å; A225-R229 VanDerWaalsContact O-N 3.11Å; A225-R229 PolarHBondContact O-NE 3.32Å; E226-R229 PolarHBondContact O-N 2.73Å; E226-R229 VanDerWaalsContact O-N 3.11Å; R229-G231 VanDerWaalsContact C-N 3.31Å; R229-L254 WeakPolarHBondContact O-CD1 3.42Å
230E94.9Very high94Very high117 Ų11776.6 Ų76.655%0.54734%0.339SS..Hα-helixtrans-69.7-29.3173.8-72.5-176.3-160.600112.6E226 K227 I228 K232E226-E230 PolarHBondContact O-N 3.36Å; K227-E230 PolarHBondContact O-N 3.26Å; I228-E230 VanDerWaalsContact C-N 3.33Å; I228-E230 PolarHBondContact O-N 3.37Å; E230-K232 PolarHBondContact O-N 2.73Å
231G94.1Very high94.5Very high19 Ų1974.2 Ų74.220%0.19633%0.329CS..THydrogen-bonded Turntrans66.817.2178.800000114K227 I228 R229K227-G231 PolarHBondContact O-N 2.8Å; K227-G231 VanDerWaalsContact O-N 3.12Å; I228-G231 PolarHBondContact O-N 2.61Å; R229-G231 VanDerWaalsContact C-N 3.31Å
232K95Very high95.2Very high160 Ų16075.6 Ų75.670%0.69634%0.336SS*.  trans-97.4123.5179.3-66.7177.1-176170.50110.2E230E230-K232 PolarHBondContact O-N 2.73Å
233F96.9Very high95.6Very high61 Ų6174.2 Ų74.227%0.26833%0.331SS..  trans-139.8162.617553.3-85.7000109.3Y207 P215 F216 L252Y207-F233 HydrophobicContact CD2-CD2 4.18Å; Y207-F233 HydrophobicContact CD2-CE2 4.44Å; Y207-F233 AromaticContact CE2-CD2 3.73Å; Y207-F233 HydrophobicContact CE2-CD2 3.73Å; Y207-F233 HydrophobicContact CE2-CE2 4.31Å; P215-F233 HydrophobicContact CB-CB 3.91Å; P215-F233 HydrophobicContact CB-CD2 4.45Å; P215-F233 HydrophobicContact CB-CG 4.16Å; P215-F233 WeakPolarHBondContact O-CB 3.31Å; F216-F233 HydrophobicContact CE1-CB 4.1Å; F216-F233 AromaticContact CE1-CD1 3.92Å; F216-F233 HydrophobicContact CE1-CD1 3.92Å; F216-F233 HydrophobicContact CE1-CG 4.48Å; F216-F233 HydrophobicContact CZ-CB 4.39Å; F216-F233 AromaticContact CZ-CD1 3.63Å; F216-F233 HydrophobicContact CZ-CD1 3.63Å; F216-F233 HydrophobicContact CZ-CE1 4.37Å; F216-F233 HydrophobicContact CZ-CG 4.36Å; F233-L252 HydrophobicContact CD1-CD1 4.41Å; F233-L252 HydrophobicContact CD2-CD1 4.27Å; F233-L252 HydrophobicContact CE1-CB 3.68Å; F233-L252 HydrophobicContact CE1-CD1 4.04Å; F233-L252 HydrophobicContact CE2-CD1 3.89Å; F233-L252 HydrophobicContact CZ-CB 3.74Å; F233-L252 HydrophobicContact CZ-CD1 3.77Å; F233-L252 HydrophobicContact CZ-CG 4.39Å
234R97.6Very high95.9Very high214 Ų21472 Ų7281%0.80832%0.321SS*.PPolyproline II helixtrans-72.1155.7179.2-65.8-177.2178.6-177.7-0.7110.1Y207Y207-R234 VanDerWaalsContact CE2-O 3.22Å; Y207-R234 WeakPolarHBondContact CE2-O 3.34Å; Y207-R234 PolarHBondContact OH-O 3.32Å
235R98.1Very high96.2Very high66 Ų6673.4 Ų73.425%0.24933%0.329CS..PPolyproline II helixtrans-59.9146.4166.1-164.8-167.7172.5-75.45.6108.9P237 Y240 E242 N245R235-P237 PolarHBondContact NH1-O 2.93Å; R235-P237 VanDerWaalsContact NH1-O 3.16Å; R235-Y240 PolarHBondContact NH2-O 3.28Å; R235-E242 IonicContact CZ-OE1 3.32Å; R235-E242 VanDerWaalsContact CZ-OE1 3.31Å; R235-E242 IonicContact CZ-OE2 3.48Å; R235-E242 IonicContact NE-OE1 3.97Å; R235-E242 PolarHBondContact NE-OE1 3.49Å; R235-E242 VanDerWaalsContact NE-OE1 3.16Å; R235-E242 IonicContact NE-OE2 2.73Å; R235-E242 IonicContact NH2-OE1 2.71Å; R235-E242 PolarHBondContact NH2-OE1 2.84Å; R235-E242 IonicContact NH2-OE2 3.17Å; R235-E242 PolarHBondContact NH2-OE2 3.26Å; R235-N245 VanDerWaalsContact CG-OD1 3.23Å; R235-N245 WeakPolarHBondContact CG-OD1 3.3Å
236I98.5Very high96.6Very high2 Ų275.1 Ų75.11%0.0134%0.342CS..PPolyproline II helixtrans-58.8159.5165.463176.8000110.3Y207 C210 Y240 L244 N245 L248Y207-I236 HydrophobicContact CD2-CG2 3.53Å; Y207-I236 HydrophobicContact CE2-CG2 3.63Å; Y207-I236 HydrophobicContact CG-CG2 4.27Å; C210-I236 HydrophobicContact CB-CB 3.98Å; C210-I236 HydrophobicContact CB-CD1 4.49Å; C210-I236 HydrophobicContact CB-CG2 3.77Å; I236-Y240 HydrophobicContact CB-CD2 4.27Å; I236-Y240 HydrophobicContact CD1-CD2 4.12Å; I236-Y240 HydrophobicContact CD1-CG 4.11Å; I236-Y240 HydrophobicContact CG1-CD2 4.27Å; I236-L244 HydrophobicContact CD1-CD2 4.36Å; I236-L244 HydrophobicContact CD1-CG 4.05Å; I236-N245 HydrophobicContact CD1-CB 3.8Å; I236-N245 HydrophobicContact CG1-CB 3.86Å; I236-L248 HydrophobicContact CD1-CD1 4.2Å; I236-L248 HydrophobicContact CG2-CD1 3.87Å
237P98.4Very high96.8Very high29 Ų2971.6 Ų71.619%0.18833%0.326CS..PPolyproline II helixtrans-51.3143.5178.2-29.535.7000113.8Y107 R235 R239 Y240Y107-P237 HydrophobicContact CD1-CG 4.39Å; Y107-P237 HydrophobicContact CE1-CG 3.77Å; R235-P237 PolarHBondContact NH1-O 2.93Å; R235-P237 VanDerWaalsContact NH1-O 3.16Å; P237-R239 HydrophobicContact CB-CG 4.14Å; P237-R239 PolarHBondContact O-N 2.78Å; P237-Y240 HydrophobicContact CB-CD2 3.99Å; P237-Y240 HydrophobicContact CB-CE2 3.89Å; P237-Y240 HydrophobicContact CG-CD2 4.32Å; P237-Y240 HydrophobicContact CG-CE2 3.91Å; P237-Y240 VanDerWaalsContact O-CD2 3.27Å; P237-Y240 WeakPolarHBondContact O-CD2 3.4Å; P237-Y240 PolarHBondContact O-N 3.06Å; P237-Y240 VanDerWaalsContact O-N 3.12Å
238F97.9Very high97Very high171 Ų17168.3 Ų68.375%0.7531%0.312SS*.THydrogen-bonded Turntrans-64.7-9.2-176.1-71.7-75.8000115.5Y240F238-Y240 PolarHBondContact O-N 3.07Å
239R97.7Very high97.1Very high124 Ų12469.7 Ų69.747%0.46833%0.327SS..THydrogen-bonded Turntrans-69.8-15172.569.8-170.3-65.5-93.94.4113.9Y107 L108 P237Y107-R239 VanDerWaalsContact CB-CZ 3.44Å; L108-R239 PolarHBondContact O-NH1 3.33Å; P237-R239 HydrophobicContact CB-CG 4.14Å; P237-R239 PolarHBondContact O-N 2.78Å
240Y98.3Very high97.4Very high4 Ų469.4 Ų69.42%0.01633%0.325CS..SBendtrans-98.3145.5177.5-55.9-69000110.8L108 E110 I113 C210 R235 I236 P237 F238 L244L108-Y240 WeakPolarHBondContact O-CE1 3.35Å; L108-Y240 PolarHBondContact O-OH 3.36Å; E110-Y240 HydrophobicContact CB-CD1 4.08Å; E110-Y240 HydrophobicContact CG-CD1 4.37Å; E110-Y240 VanDerWaalsContact OE2-CA 3.24Å; E110-Y240 WeakPolarHBondContact OE2-CA 3.37Å; I113-Y240 HydrophobicContact CD1-CD1 4.27Å; I113-Y240 HydrophobicContact CD1-CE1 3.51Å; C210-Y240 WeakPolarHBondContact CA-OH 3.44Å; C210-Y240 HydrophobicContact CB-CD2 3.96Å; C210-Y240 HydrophobicContact CB-CE2 3.63Å; C210-Y240 WeakPolarHBondContact O-CE2 3.4Å; C210-Y240 PolarHBondContact O-OH 3.24Å; R235-Y240 PolarHBondContact NH2-O 3.28Å; I236-Y240 HydrophobicContact CB-CD2 4.27Å; I236-Y240 HydrophobicContact CD1-CD2 4.12Å; I236-Y240 HydrophobicContact CD1-CG 4.11Å; I236-Y240 HydrophobicContact CG1-CD2 4.27Å; P237-Y240 HydrophobicContact CB-CD2 3.99Å; P237-Y240 HydrophobicContact CB-CE2 3.89Å; P237-Y240 HydrophobicContact CG-CD2 4.32Å; P237-Y240 HydrophobicContact CG-CE2 3.91Å; P237-Y240 VanDerWaalsContact O-CD2 3.27Å; P237-Y240 WeakPolarHBondContact O-CD2 3.4Å; P237-Y240 PolarHBondContact O-N 3.06Å; P237-Y240 VanDerWaalsContact O-N 3.12Å; F238-Y240 PolarHBondContact O-N 3.07Å; Y240-L244 HydrophobicContact CD1-CD2 4.33Å; Y240-L244 HydrophobicContact CG-CD2 4.48Å
241S97.9Very high97.6Very high29 Ų2963.8 Ų63.820%0.20330%0.299CS..  trans-54.9151.7-179.566.70000113.4E110 E243 L244 N245E110-S241 VanDerWaalsContact OE1-CB 3.23Å; E110-S241 WeakPolarHBondContact OE1-CB 3.44Å; E110-S241 PolarHBondContact OE1-OG 3.04Å; E110-S241 PolarHBondContact OE2-N 3.5Å; S241-E243 WeakPolarHBondContact CB-OE2 3.34Å; S241-E243 PolarHBondContact O-N 3.09Å; S241-L244 PolarHBondContact O-N 3.11Å; S241-L244 VanDerWaalsContact OG-CB 3.3Å; S241-L244 WeakPolarHBondContact OG-CB 3.46Å; S241-L244 PolarHBondContact OG-N 2.8Å; S241-N245 PolarHBondContact O-N 3.02Å
242E97.6Very high97.8Very high103 Ų10363.1 Ų63.148%0.48129%0.291SS..Hα-helixtrans-67.1-30.4174.2-74.9-59.1156.700111.2R235 N245 A246R235-E242 IonicContact CZ-OE1 3.32Å; R235-E242 VanDerWaalsContact CZ-OE1 3.31Å; R235-E242 IonicContact CZ-OE2 3.48Å; R235-E242 IonicContact NE-OE1 3.97Å; R235-E242 PolarHBondContact NE-OE1 3.49Å; R235-E242 VanDerWaalsContact NE-OE1 3.16Å; R235-E242 IonicContact NE-OE2 2.73Å; R235-E242 IonicContact NH2-OE1 2.71Å; R235-E242 PolarHBondContact NH2-OE1 2.84Å; R235-E242 IonicContact NH2-OE2 3.17Å; R235-E242 PolarHBondContact NH2-OE2 3.26Å; E242-N245 PolarHBondContact O-N 3.41Å; E242-N245 PolarHBondContact OE2-ND2 2.86Å; E242-A246 VanDerWaalsContact O-CB 3.23Å; E242-A246 WeakPolarHBondContact O-CB 3.5Å; E242-A246 PolarHBondContact O-N 3.4Å
243E96.8Very high97.9Very high121 Ų12157.9 Ų57.957%0.56527%0.271SS*.Hα-helixtrans-61.1-46.8175.9-66.576.3-170.900111.4S241 A246 L247 L270S241-E243 WeakPolarHBondContact CB-OE2 3.34Å; S241-E243 PolarHBondContact O-N 3.09Å; E243-A246 PolarHBondContact O-N 2.65Å; E243-L247 WeakPolarHBondContact O-CB 3.03Å; E243-L247 PolarHBondContact O-N 3.02Å; E243-L270 HydrophobicContact CB-CD1 4.18Å
244L97.9Very high97.9Very high0 Ų058.3 Ų58.30%028%0.275CS..Hα-helixtrans-63.8-47.4175.4176.754.8000111.1E110 I113 L114 M117 I236 Y240 S241 A246 L247 L248 L270E110-L244 HydrophobicContact CG-CD2 3.92Å; I113-L244 HydrophobicContact CG2-CD2 4.41Å; L114-L244 HydrophobicContact CD2-CD1 4.17Å; M117-L244 HydrophobicContact CE-CD1 3.29Å; I236-L244 HydrophobicContact CD1-CD2 4.36Å; I236-L244 HydrophobicContact CD1-CG 4.05Å; Y240-L244 HydrophobicContact CD1-CD2 4.33Å; Y240-L244 HydrophobicContact CG-CD2 4.48Å; S241-L244 PolarHBondContact O-N 3.11Å; S241-L244 VanDerWaalsContact OG-CB 3.3Å; S241-L244 WeakPolarHBondContact OG-CB 3.46Å; S241-L244 PolarHBondContact OG-N 2.8Å; L244-A246 VanDerWaalsContact C-N 3.33Å; L244-A246 PolarHBondContact O-N 3.11Å; L244-L247 PolarHBondContact O-N 3.34Å; L244-L248 HydrophobicContact CD1-CD1 4.27Å; L244-L248 HydrophobicContact CD1-CG 4.15Å; L244-L248 HydrophobicContact CG-CD1 4.39Å; L244-L248 WeakPolarHBondContact O-CG 3.49Å; L244-L248 PolarHBondContact O-N 2.98Å; L244-L270 HydrophobicContact CB-CD2 4Å; L244-L270 HydrophobicContact CD1-CD2 4.18Å
245N98.3Very high97.8Very high33 Ų3353.3 Ų53.318%0.17626%0.26CS..Hα-helixtrans-57.8-45.2177.8178.262.1000112R235 I236 S241 E242 L248 G249R235-N245 VanDerWaalsContact CG-OD1 3.23Å; R235-N245 WeakPolarHBondContact CG-OD1 3.3Å; I236-N245 HydrophobicContact CD1-CB 3.8Å; I236-N245 HydrophobicContact CG1-CB 3.86Å; S241-N245 PolarHBondContact O-N 3.02Å; E242-N245 PolarHBondContact O-N 3.41Å; E242-N245 PolarHBondContact OE2-ND2 2.86Å; N245-L248 PolarHBondContact O-N 3.35Å; N245-G249 PolarHBondContact O-N 3.38Å
246A97.8Very high97.6Very high53 Ų5352.4 Ų52.444%0.43826%0.26SS..Hα-helixtrans-65.5-39.4178.800000112.3E242 E243 L244 G249 R250E242-A246 VanDerWaalsContact O-CB 3.23Å; E242-A246 WeakPolarHBondContact O-CB 3.5Å; E242-A246 PolarHBondContact O-N 3.4Å; E243-A246 PolarHBondContact O-N 2.65Å; L244-A246 VanDerWaalsContact C-N 3.33Å; L244-A246 PolarHBondContact O-N 3.11Å; A246-G249 PolarHBondContact O-N 3.37Å; A246-R250 WeakPolarHBondContact O-CG 3.42Å; A246-R250 PolarHBondContact O-N 3.35Å
247L97.9Very high97.4Very high3 Ų359.2 Ų59.22%0.01629%0.286CS..Hα-helixtrans-64.4-45.7175.3178.958.2000111.6M117 E243 L244 G249 R250 M251 P260 I265 L270M117-L247 HydrophobicContact CE-CD2 4.22Å; M117-L247 HydrophobicContact SD-CD2 3.51Å; M117-L247 VanDerWaalsContact SD-CD2 3.51Å; E243-L247 WeakPolarHBondContact O-CB 3.03Å; E243-L247 PolarHBondContact O-N 3.02Å; L244-L247 PolarHBondContact O-N 3.34Å; L247-G249 VanDerWaalsContact C-N 3.28Å; L247-G249 PolarHBondContact O-N 3.01Å; L247-R250 PolarHBondContact O-N 3.48Å; L247-R250 VanDerWaalsContact O-N 3.1Å; L247-M251 HydrophobicContact CG-SD 4.36Å; L247-M251 WeakPolarHBondContact O-CG 3.33Å; L247-M251 PolarHBondContact O-N 3.1Å; L247-P260 HydrophobicContact CD1-CG 4.29Å; L247-I265 HydrophobicContact CD1-CG1 4.44Å; L247-L270 HydrophobicContact CD2-CD2 4.27Å
248L98.2Very high97.3Very high1 Ų162.1 Ų62.11%0.00530%0.3CS..Hα-helixtrans-60.8-39.3174.6-66.4180000111.8L206 I236 L244 N245 R250 M251 L252L206-L248 HydrophobicContact CB-CD2 3.5Å; L206-L248 HydrophobicContact CD1-CD2 4.13Å; L206-L248 HydrophobicContact CG-CD2 4.49Å; I236-L248 HydrophobicContact CD1-CD1 4.2Å; I236-L248 HydrophobicContact CG2-CD1 3.87Å; L244-L248 HydrophobicContact CD1-CD1 4.27Å; L244-L248 HydrophobicContact CD1-CG 4.15Å; L244-L248 HydrophobicContact CG-CD1 4.39Å; L244-L248 WeakPolarHBondContact O-CG 3.49Å; L244-L248 PolarHBondContact O-N 2.98Å; N245-L248 PolarHBondContact O-N 3.35Å; L248-R250 VanDerWaalsContact C-N 3.3Å; L248-R250 PolarHBondContact O-N 2.85Å; L248-M251 HydrophobicContact CD2-SD 4.25Å; L248-M251 PolarHBondContact O-N 3.13Å; L248-L252 WeakPolarHBondContact O-CB 3.45Å; L248-L252 WeakPolarHBondContact O-CG 3.4Å; L248-L252 PolarHBondContact O-N 3.24Å
249G98Very high97.3Very high30 Ų3054.2 Ų54.231%0.30927%0.265SS..Hα-helixtrans-56.7-40.5172.600000113.4N245 A246 L247N245-G249 PolarHBondContact O-N 3.38Å; A246-G249 PolarHBondContact O-N 3.37Å; L247-G249 VanDerWaalsContact C-N 3.28Å; L247-G249 PolarHBondContact O-N 3.01Å
250R98.1Very high97.3Very high117 Ų11748.8 Ų48.844%0.44225%0.246SC..Hα-helixtrans-71.5-38175.3-69.3-173.5-69.1150.4-5.2112.8A246 L247 L248 L252 N253A246-R250 WeakPolarHBondContact O-CG 3.42Å; A246-R250 PolarHBondContact O-N 3.35Å; L247-R250 PolarHBondContact O-N 3.48Å; L247-R250 VanDerWaalsContact O-N 3.1Å; L248-R250 VanDerWaalsContact C-N 3.3Å; L248-R250 PolarHBondContact O-N 2.85Å; R250-L252 VanDerWaalsContact C-N 3.32Å; R250-N253 WeakPolarHBondContact O-CB 3.49Å; R250-N253 PolarHBondContact O-N 3.04Å
251M98.4Very high97.1Very high0 Ų050.5 Ų50.50%026%0.259CS..Hα-helixtrans-66-35.7177-66.6176.575.900112.3I199 L202 L206 L247 L248 N253 R259 P260 I265I199-M251 HydrophobicContact CG2-CB 4.15Å; I199-M251 HydrophobicContact CG2-CE 4.01Å; I199-M251 HydrophobicContact CG2-CG 3.99Å; I199-M251 WeakPolarHBondContact O-CE 3.27Å; L202-M251 HydrophobicContact CB-CE 3.83Å; L202-M251 HydrophobicContact CD2-CE 3.7Å; L202-M251 HydrophobicContact CG-CE 3.62Å; L206-M251 HydrophobicContact CD1-CE 3.98Å; L206-M251 HydrophobicContact CD1-SD 4.15Å; L247-M251 HydrophobicContact CG-SD 4.36Å; L247-M251 WeakPolarHBondContact O-CG 3.33Å; L247-M251 PolarHBondContact O-N 3.1Å; L248-M251 HydrophobicContact CD2-SD 4.25Å; L248-M251 PolarHBondContact O-N 3.13Å; M251-N253 VanDerWaalsContact C-N 3.27Å; M251-N253 PolarHBondContact O-N 2.94Å; M251-R259 WeakPolarHBondContact O-CD 3.08Å; M251-P260 HydrophobicContact CG-CG 3.97Å; M251-I265 HydrophobicContact CE-CD1 4.07Å; M251-I265 HydrophobicContact CG-CD1 4.5Å; M251-I265 HydrophobicContact SD-CD1 4.38Å
252L98.2Very high97Very high4 Ų449.4 Ų49.42%0.02125%0.25CS..THydrogen-bonded Turntrans-90.626.8178.2-63.4177.5000113.1W200 C204 Y207 P215 F233 L248 R250W200-L252 HydrophobicContact CD2-CD2 4.13Å; W200-L252 HydrophobicContact CE3-CD2 4.35Å; W200-L252 VanDerWaalsContact CZ3-C 3.46Å; W200-L252 HydrophobicContact CZ3-CB 4.46Å; W200-L252 VanDerWaalsContact CZ3-O 3.24Å; W200-L252 WeakPolarHBondContact CZ3-O 3.18Å; C204-L252 VanDerWaalsContact SG-CD2 3.57Å; Y207-L252 HydrophobicContact CD2-CD1 4.37Å; P215-L252 HydrophobicContact CB-CD1 4.06Å; P215-L252 HydrophobicContact CG-CD1 4.12Å; F233-L252 HydrophobicContact CD1-CD1 4.41Å; F233-L252 HydrophobicContact CD2-CD1 4.27Å; F233-L252 HydrophobicContact CE1-CB 3.68Å; F233-L252 HydrophobicContact CE1-CD1 4.04Å; F233-L252 HydrophobicContact CE2-CD1 3.89Å; F233-L252 HydrophobicContact CZ-CB 3.74Å; F233-L252 HydrophobicContact CZ-CD1 3.77Å; F233-L252 HydrophobicContact CZ-CG 4.39Å; L248-L252 WeakPolarHBondContact O-CB 3.45Å; L248-L252 WeakPolarHBondContact O-CG 3.4Å; L248-L252 PolarHBondContact O-N 3.24Å; R250-L252 VanDerWaalsContact C-N 3.32Å
253N98Very high96.7Very high51 Ų5148.3 Ų48.327%0.27325%0.245SC..  trans-73.8136.3174.5-162.1-68.9000110.9W200 R250 M251 K255 L258 R259W200-N253 WeakPolarHBondContact CZ3-O 3.39Å; R250-N253 WeakPolarHBondContact O-CB 3.49Å; R250-N253 PolarHBondContact O-N 3.04Å; M251-N253 VanDerWaalsContact C-N 3.27Å; M251-N253 PolarHBondContact O-N 2.94Å; N253-K255 PolarHBondContact O-N 2.85Å; N253-K255 PolarHBondContact OD1-N 2.93Å; N253-L258 HydrophobicContact CB-CB 4.24Å; N253-R259 HydrophobicContact CB-CG 4.2Å; N253-R259 PolarHBondContact O-NE 2.78Å; N253-R259 PolarHBondContact O-NH2 3.25Å
254L96Very high96.6Very high70 Ų7044.9 Ų44.937%0.36624%0.235SC..SBendtrans-56.1-39177.2-69.3178.3000112.3P185 W200 I228 R229 R259P185-L254 HydrophobicContact CG-CD2 3.91Å; W200-L254 HydrophobicContact CH2-CD2 4.43Å; I228-L254 WeakPolarHBondContact O-CD2 3.44Å; R229-L254 WeakPolarHBondContact O-CD1 3.42Å; L254-R259 PolarHBondContact O-NH2 2.84Å
255K94.8Very high96.5Very high109 Ų10944.9 Ų44.947%0.47424%0.235SC..SBendtrans-86.3115.1179.7-63.7168.6162-155.60109.2N253 Y257 L258 R259N253-K255 PolarHBondContact O-N 2.85Å; N253-K255 PolarHBondContact OD1-N 2.93Å; K255-Y257 VanDerWaalsContact C-N 3.29Å; K255-Y257 HydrophobicContact CB-CD1 4.22Å; K255-Y257 HydrophobicContact CB-CD2 4.49Å; K255-Y257 HydrophobicContact CB-CE1 3.82Å; K255-Y257 HydrophobicContact CB-CE2 4.1Å; K255-Y257 HydrophobicContact CD-CE1 4.36Å; K255-Y257 HydrophobicContact CD-CE2 4.07Å; K255-Y257 WeakPolarHBondContact CD-OH 3.45Å; K255-Y257 VanDerWaalsContact CE-OH 3.27Å; K255-Y257 WeakPolarHBondContact CE-OH 3.04Å; K255-Y257 HydrophobicContact CG-CE1 4.14Å; K255-Y257 PolarHBondContact NZ-OH 2.92Å; K255-Y257 PolarHBondContact O-N 3.47Å; K255-L258 HydrophobicContact CB-CB 4.25Å; K255-L258 HydrophobicContact CB-CD1 3.93Å; K255-L258 HydrophobicContact CB-CG 3.92Å; K255-L258 HydrophobicContact CD-CD1 3.66Å; K255-L258 HydrophobicContact CD-CG 4.33Å; K255-L258 HydrophobicContact CG-CD1 4.37Å; K255-L258 WeakPolarHBondContact O-CB 3.21Å; K255-L258 PolarHBondContact O-N 2.99Å; K255-R259 PolarHBondContact O-N 3.09Å
256D94.4Very high96.3Very high47 Ų4744.2 Ų44.225%0.25123%0.231SC..G310 helixtrans-56.5-38.2-179.365.4-17.9000113.8N194 K196 L258 R259N194-D256 PolarHBondContact ND2-OD2 3.39Å; K196-D256 HydrophobicContact CB-CB 3.88Å; K196-D256 HydrophobicContact CG-CB 4.49Å; K196-D256 WeakPolarHBondContact CG-O 3.29Å; K196-D256 PolarHBondContact NZ-O 2.93Å; D256-L258 PolarHBondContact O-N 3.25Å; D256-R259 WeakPolarHBondContact O-CB 3.22Å; D256-R259 PolarHBondContact O-N 3.03Å; D256-R259 VanDerWaalsContact O-N 3.1Å
257Y94.2Very high96Very high144 Ų14449.3 Ų49.357%0.56525%0.246SC*.G310 helixtrans-68-21.1176.757.5-96.6000113.8K255K255-Y257 VanDerWaalsContact C-N 3.29Å; K255-Y257 HydrophobicContact CB-CD1 4.22Å; K255-Y257 HydrophobicContact CB-CD2 4.49Å; K255-Y257 HydrophobicContact CB-CE1 3.82Å; K255-Y257 HydrophobicContact CB-CE2 4.1Å; K255-Y257 HydrophobicContact CD-CE1 4.36Å; K255-Y257 HydrophobicContact CD-CE2 4.07Å; K255-Y257 WeakPolarHBondContact CD-OH 3.45Å; K255-Y257 VanDerWaalsContact CE-OH 3.27Å; K255-Y257 WeakPolarHBondContact CE-OH 3.04Å; K255-Y257 HydrophobicContact CG-CE1 4.14Å; K255-Y257 PolarHBondContact NZ-OH 2.92Å; K255-Y257 PolarHBondContact O-N 3.47Å
258L96.6Very high95.7Very high91 Ų9150 Ų5048%0.47625%0.251SS..G310 helixtrans-84.9-13.3173.3-64-176.9000112.8N253 K255 D256N253-L258 HydrophobicContact CB-CB 4.24Å; K255-L258 HydrophobicContact CB-CB 4.25Å; K255-L258 HydrophobicContact CB-CD1 3.93Å; K255-L258 HydrophobicContact CB-CG 3.92Å; K255-L258 HydrophobicContact CD-CD1 3.66Å; K255-L258 HydrophobicContact CD-CG 4.33Å; K255-L258 HydrophobicContact CG-CD1 4.37Å; K255-L258 WeakPolarHBondContact O-CB 3.21Å; K255-L258 PolarHBondContact O-N 2.99Å; D256-L258 PolarHBondContact O-N 3.25Å
259R98Very high95.4Very high4 Ų455 Ų552%0.01529%0.286CS..SBendtrans-71.1137.1174.6-55.5177.7-161.3147.28.9109.2E186 K196 I199 M251 N253 L254 K255 D256E186-R259 IonicContact OE1-CZ 3.44Å; E186-R259 IonicContact OE1-NH1 2.74Å; E186-R259 PolarHBondContact OE1-NH1 3.15Å; E186-R259 IonicContact OE1-NH2 3.5Å; E186-R259 IonicContact OE2-CZ 3.7Å; E186-R259 IonicContact OE2-NH1 2.82Å; E186-R259 PolarHBondContact OE2-NH1 3.31Å; E186-R259 IonicContact OE2-NH2 3.33Å; E186-R259 PolarHBondContact OE2-NH2 3.4Å; K196-R259 HydrophobicContact CD-CB 4.46Å; K196-R259 PolarHBondContact NZ-O 3.22Å; K196-R259 WeakPolarHBondContact O-CD 3.4Å; K196-R259 PolarHBondContact O-NH1 3.35Å; I199-R259 HydrophobicContact CG2-CB 4.12Å; M251-R259 WeakPolarHBondContact O-CD 3.08Å; N253-R259 HydrophobicContact CB-CG 4.2Å; N253-R259 PolarHBondContact O-NE 2.78Å; N253-R259 PolarHBondContact O-NH2 3.25Å; L254-R259 PolarHBondContact O-NH2 2.84Å; K255-R259 PolarHBondContact O-N 3.09Å; D256-R259 WeakPolarHBondContact O-CB 3.22Å; D256-R259 PolarHBondContact O-N 3.03Å; D256-R259 VanDerWaalsContact O-N 3.1Å
260P97.3Very high95Very high10 Ų1055.2 Ų55.27%0.06528%0.28CS..PPolyproline II helixtrans-63.7146.7179.928.9-34.8000110.3L247 M251 I265L247-P260 HydrophobicContact CD1-CG 4.29Å; M251-P260 HydrophobicContact CG-CG 3.97Å; P260-I265 HydrophobicContact CB-CG1 3.91Å; P260-I265 HydrophobicContact CG-CD1 4.07Å; P260-I265 HydrophobicContact CG-CG1 3.74Å
261S95.3Very high94.6Very high41 Ų4149.6 Ų49.629%0.28726%0.259SS..PPolyproline II helixtrans-72.3166.9169.880.60000110.7E263 S264 I265S261-E263 VanDerWaalsContact CB-OE2 3.32Å; S261-E263 WeakPolarHBondContact CB-OE2 3.09Å; S261-E263 PolarHBondContact O-N 3.31Å; S261-E263 PolarHBondContact OG-N 2.96Å; S261-E263 PolarHBondContact OG-OE2 2.9Å; S261-S264 PolarHBondContact O-N 2.81Å; S261-S264 VanDerWaalsContact O-N 3.15Å; S261-S264 PolarHBondContact OG-N 3.16Å; S261-I265 WeakPolarHBondContact O-CG1 3.27Å; S261-I265 PolarHBondContact O-N 3.3Å
262V94.4Very high93.9Very high5 Ų552.3 Ų52.33%0.0328%0.277CS..Hα-helixtrans-54.7-42.6173.3173.30000111.2T121 L124 K125 I199 I265 L266T121-V262 HydrophobicContact CG2-CB 4.35Å; T121-V262 HydrophobicContact CG2-CG1 3.67Å; T121-V262 WeakPolarHBondContact O-CG1 3.26Å; L124-V262 HydrophobicContact CB-CG2 4.28Å; K125-V262 HydrophobicContact CB-CG1 3.48Å; K125-V262 VanDerWaalsContact CB-CG1 3.48Å; K125-V262 HydrophobicContact CD-CG1 4.48Å; K125-V262 HydrophobicContact CG-CG1 3.89Å; I199-V262 HydrophobicContact CD1-CG2 3.89Å; V262-I265 PolarHBondContact O-N 3.05Å; V262-L266 HydrophobicContact CG1-CD1 4.07Å; V262-L266 VanDerWaalsContact O-CG 3.31Å; V262-L266 WeakPolarHBondContact O-CG 3.45Å; V262-L266 PolarHBondContact O-N 3.06Å; V262-L266 VanDerWaalsContact O-N 3.08Å
263E93.1Very high93.1Very high81 Ų8158.2 Ų58.238%0.37931%0.309SS..Hα-helixtrans-62.8-45.6177.1-60.868.7-148.400111.3S261 I265 L266 Q267S261-E263 VanDerWaalsContact CB-OE2 3.32Å; S261-E263 WeakPolarHBondContact CB-OE2 3.09Å; S261-E263 PolarHBondContact O-N 3.31Å; S261-E263 PolarHBondContact OG-N 2.96Å; S261-E263 PolarHBondContact OG-OE2 2.9Å; E263-I265 VanDerWaalsContact C-N 3.31Å; E263-I265 PolarHBondContact O-N 3.18Å; E263-L266 PolarHBondContact O-N 2.56Å; E263-Q267 WeakPolarHBondContact O-CB 3.16Å; E263-Q267 VanDerWaalsContact O-CG 3.28Å; E263-Q267 WeakPolarHBondContact O-CG 3.39Å; E263-Q267 PolarHBondContact O-N 3.2Å
264S94.6Very high92.5Very high49 Ų4956.2 Ų56.234%0.34330%0.299SS..Hα-helixtrans-62.9-37.6179.6-179.50000112.2S261 S268S261-S264 PolarHBondContact O-N 2.81Å; S261-S264 VanDerWaalsContact O-N 3.15Å; S261-S264 PolarHBondContact OG-N 3.16Å; S264-S268 PolarHBondContact O-N 2.72Å
265I95.7Very high91.9Very high0 Ų053.4 Ų53.40%029%0.285CS..Hα-helixtrans-65.2-49175.1-65.2167.5000110.1M117 T121 I199 L247 M251 P260 S261 V262 E263 Q267 S268 L271M117-I265 HydrophobicContact CG-CG2 4.47Å; M117-I265 HydrophobicContact SD-CG2 4.37Å; T121-I265 HydrophobicContact CG2-CB 3.98Å; T121-I265 HydrophobicContact CG2-CG2 3.85Å; I199-I265 HydrophobicContact CD1-CD1 3.93Å; I199-I265 HydrophobicContact CG2-CD1 4.22Å; L247-I265 HydrophobicContact CD1-CG1 4.44Å; M251-I265 HydrophobicContact CE-CD1 4.07Å; M251-I265 HydrophobicContact CG-CD1 4.5Å; M251-I265 HydrophobicContact SD-CD1 4.38Å; P260-I265 HydrophobicContact CB-CG1 3.91Å; P260-I265 HydrophobicContact CG-CD1 4.07Å; P260-I265 HydrophobicContact CG-CG1 3.74Å; S261-I265 WeakPolarHBondContact O-CG1 3.27Å; S261-I265 PolarHBondContact O-N 3.3Å; V262-I265 PolarHBondContact O-N 3.05Å; E263-I265 VanDerWaalsContact C-N 3.31Å; E263-I265 PolarHBondContact O-N 3.18Å; I265-Q267 PolarHBondContact O-N 3.31Å; I265-S268 VanDerWaalsContact O-CB 3.26Å; I265-S268 WeakPolarHBondContact O-CB 3.5Å; I265-S268 PolarHBondContact O-N 3.05Å; I265-S268 PolarHBondContact O-OG 3.49Å; I265-L271 HydrophobicContact CG2-CD1 3.63Å
266L93.3Very high91.4Very high18 Ų1849.9 Ų49.99%0.09428%0.276CS..Hα-helixtrans-65.1-25.8-178.6-67.3170.8000113.6T121 L122 K125 V262 E263 S268 V275T121-L266 HydrophobicContact CG2-CD1 4.18Å; T121-L266 HydrophobicContact CG2-CD2 3.71Å; T121-L266 HydrophobicContact CG2-CG 3.59Å; L122-L266 HydrophobicContact CD2-CD1 4.01Å; L122-L266 HydrophobicContact CD2-CD2 4.06Å; L122-L266 HydrophobicContact CG-CD2 3.97Å; K125-L266 HydrophobicContact CD-CD1 3.87Å; V262-L266 HydrophobicContact CG1-CD1 4.07Å; V262-L266 VanDerWaalsContact O-CG 3.31Å; V262-L266 WeakPolarHBondContact O-CG 3.45Å; V262-L266 PolarHBondContact O-N 3.06Å; V262-L266 VanDerWaalsContact O-N 3.08Å; E263-L266 PolarHBondContact O-N 2.56Å; L266-S268 VanDerWaalsContact C-N 3.32Å; L266-V275 HydrophobicContact CD2-CG2 3.64Å
267Q91.7Very high90.9Very high160 Ų16051.4 Ų51.475%0.74828%0.282SS*.THydrogen-bonded Turntrans-85.1-3.6175.9-71.5171.5-11.200113.4E263 I265E263-Q267 WeakPolarHBondContact O-CB 3.16Å; E263-Q267 VanDerWaalsContact O-CG 3.28Å; E263-Q267 WeakPolarHBondContact O-CG 3.39Å; E263-Q267 PolarHBondContact O-N 3.2Å; I265-Q267 PolarHBondContact O-N 3.31Å
268S92.4Very high90.4Very high18 Ų1845 Ų4513%0.12626%0.257CS..SBendtrans-64.5140.3177.269.10000111.1S264 I265 L266 L270 L271 S272S264-S268 PolarHBondContact O-N 2.72Å; I265-S268 VanDerWaalsContact O-CB 3.26Å; I265-S268 WeakPolarHBondContact O-CB 3.5Å; I265-S268 PolarHBondContact O-N 3.05Å; I265-S268 PolarHBondContact O-OG 3.49Å; L266-S268 VanDerWaalsContact C-N 3.32Å; S268-L270 PolarHBondContact O-N 3.1Å; S268-L270 VanDerWaalsContact O-N 3.15Å; S268-L271 PolarHBondContact O-N 3.43Å; S268-S272 PolarHBondContact O-N 3.5Å
269S90.7Very high89.7Confident105 Ų10545.2 Ų45.273%0.73426%0.255SS*.THydrogen-bonded Turntrans-57.3-28.1175.650.60000112.7L271 S272S269-L271 VanDerWaalsContact C-N 3.25Å; S269-L271 PolarHBondContact O-N 3.31Å; S269-S272 PolarHBondContact O-OG 2.85Å
270L90.7Very high89Confident35 Ų3552.4 Ų52.418%0.18328%0.283CS..THydrogen-bonded Turntrans-64.1-29.7176.5-170.966.6000112.8L114 E243 L244 L247 S268L114-L270 HydrophobicContact CD1-CD1 3.87Å; L114-L270 HydrophobicContact CD1-CG 4.07Å; L114-L270 HydrophobicContact CD2-CD1 4.08Å; L114-L270 HydrophobicContact CD2-CD2 3.6Å; L114-L270 HydrophobicContact CD2-CG 3.6Å; L114-L270 HydrophobicContact CG-CG 4.48Å; E243-L270 HydrophobicContact CB-CD1 4.18Å; L244-L270 HydrophobicContact CB-CD2 4Å; L244-L270 HydrophobicContact CD1-CD2 4.18Å; L247-L270 HydrophobicContact CD2-CD2 4.27Å; S268-L270 PolarHBondContact O-N 3.1Å; S268-L270 VanDerWaalsContact O-N 3.15Å
271L89.7Confident88.2Confident0 Ų054.9 Ų54.90%029%0.292CS..THydrogen-bonded Turntrans-109.4-6.6-174.9-64-173.8000114L114 M117 A118 I265 S268 S269 D273 S274 V275L114-L271 HydrophobicContact CB-CD2 4.1Å; L114-L271 HydrophobicContact CD2-CD2 4.08Å; M117-L271 HydrophobicContact CB-CD2 4.19Å; M117-L271 HydrophobicContact CG-CD1 3.86Å; M117-L271 HydrophobicContact CG-CD2 4.26Å; M117-L271 HydrophobicContact SD-CD1 3.73Å; M117-L271 HydrophobicContact SD-CD2 3.95Å; M117-L271 HydrophobicContact SD-CG 4.15Å; A118-L271 HydrophobicContact CB-CD2 4.42Å; I265-L271 HydrophobicContact CG2-CD1 3.63Å; S268-L271 PolarHBondContact O-N 3.43Å; S269-L271 VanDerWaalsContact C-N 3.25Å; S269-L271 PolarHBondContact O-N 3.31Å; L271-D273 VanDerWaalsContact C-N 3.25Å; L271-D273 PolarHBondContact O-N 3.22Å; L271-D273 VanDerWaalsContact O-N 3.16Å; L271-S274 PolarHBondContact O-N 3.4Å; L271-V275 HydrophobicContact CB-CG2 3.99Å; L271-V275 WeakPolarHBondContact O-CB 3.43Å; L271-V275 VanDerWaalsContact O-CG2 3.26Å; L271-V275 WeakPolarHBondContact O-CG2 3.47Å; L271-V275 PolarHBondContact O-N 2.99Å
272S82.9Confident87.3Confident56 Ų5655.8 Ų55.839%0.39230%0.296SS..Hα-helixtrans-51.4-45.2-173.956.80000112.6S268 S269 A276S268-S272 PolarHBondContact O-N 3.5Å; S269-S272 PolarHBondContact O-OG 2.85Å; S272-A276 VanDerWaalsContact O-CB 3.25Å; S272-A276 WeakPolarHBondContact O-CB 3.18Å; S272-A276 PolarHBondContact O-N 3.48Å
273D81.8Confident86.4Confident129 Ų12961.1 Ų61.169%0.6932%0.321SS*.Hα-helixtrans-71.5-46.1-176.8-64.3-10.7000111.6L271 V275 A276 E277L271-D273 VanDerWaalsContact C-N 3.25Å; L271-D273 PolarHBondContact O-N 3.22Å; L271-D273 VanDerWaalsContact O-N 3.16Å; D273-V275 PolarHBondContact O-N 3.18Å; D273-A276 PolarHBondContact O-N 3.08Å; D273-E277 WeakPolarHBondContact O-CB 3.45Å; D273-E277 PolarHBondContact O-N 3.32Å
274S84.1Confident85.5Confident9 Ų959.8 Ų59.86%0.06332%0.323CS..Hα-helixtrans-62.6-42.9177.7-71.80000111.3L271 E277 E278L271-S274 PolarHBondContact O-N 3.4Å; S274-E277 PolarHBondContact O-N 2.57Å; S274-E278 WeakPolarHBondContact O-CG 3.42Å; S274-E278 PolarHBondContact O-N 2.78Å
275V85.2Confident84.3Confident10 Ų1062.6 Ų62.66%0.06133%0.326CS..Hα-helixtrans-66.8-44.1178.31730000110.7A118 L266 L271 D273 E277 E278 Q279A118-V275 HydrophobicContact CB-CG2 4Å; L266-V275 HydrophobicContact CD2-CG2 3.64Å; L271-V275 HydrophobicContact CB-CG2 3.99Å; L271-V275 WeakPolarHBondContact O-CB 3.43Å; L271-V275 VanDerWaalsContact O-CG2 3.26Å; L271-V275 WeakPolarHBondContact O-CG2 3.47Å; L271-V275 PolarHBondContact O-N 2.99Å; D273-V275 PolarHBondContact O-N 3.18Å; V275-E277 VanDerWaalsContact C-N 3.32Å; V275-E277 PolarHBondContact O-N 3.3Å; V275-E278 PolarHBondContact O-N 2.75Å; V275-Q279 HydrophobicContact CG1-CG 4.36Å; V275-Q279 WeakPolarHBondContact O-CB 3.41Å; V275-Q279 VanDerWaalsContact O-CG 3.29Å; V275-Q279 WeakPolarHBondContact O-CG 3.3Å; V275-Q279 PolarHBondContact O-N 3.17Å
276A84.1Confident83Confident36 Ų3665.4 Ų65.430%0.29835%0.349SS..Hα-helixtrans-64.1-36.9176.800000112.3S272 D273 R280S272-A276 VanDerWaalsContact O-CB 3.25Å; S272-A276 WeakPolarHBondContact O-CB 3.18Å; S272-A276 PolarHBondContact O-N 3.48Å; D273-A276 PolarHBondContact O-N 3.08Å; A276-R280 WeakPolarHBondContact O-CB 3.41Å; A276-R280 WeakPolarHBondContact O-CG 3.39Å; A276-R280 PolarHBondContact O-N 3.26Å; A276-R280 VanDerWaalsContact O-N 3.15Å; A276-R280 PolarHBondContact O-NE 3.09Å
277E84.3Confident81.6Confident78 Ų7870.7 Ų70.736%0.36437%0.373SS..Hα-helixtrans-64.6-47.2173.7-164.5-166.314800111.6D273 S274 V275 R280 K281D273-E277 WeakPolarHBondContact O-CB 3.45Å; D273-E277 PolarHBondContact O-N 3.32Å; S274-E277 PolarHBondContact O-N 2.57Å; V275-E277 VanDerWaalsContact C-N 3.32Å; V275-E277 PolarHBondContact O-N 3.3Å; E277-R280 PolarHBondContact O-N 3.45Å; E277-K281 WeakPolarHBondContact O-CG 3.44Å; E277-K281 PolarHBondContact O-N 3.42Å; E277-K281 WeakPolarHBondContact OE1-CE 3.37Å; E277-K281 IonicContact OE1-NZ 2.86Å; E277-K281 PolarHBondContact OE1-NZ 3.41Å
278E83.6Confident80.1Confident9 Ų972.9 Ų72.94%0.04238%0.375CS..Hα-helixtrans-63.5-44.5178.6-71.3-54.2133.800112Q119 L122 S274 V275 R280 K281 V282Q119-E278 HydrophobicContact CG-CG 3.83Å; Q119-E278 PolarHBondContact NE2-OE1 3.49Å; Q119-E278 PolarHBondContact NE2-OE2 2.75Å; L122-E278 HydrophobicContact CD1-CB 3.95Å; S274-E278 WeakPolarHBondContact O-CG 3.42Å; S274-E278 PolarHBondContact O-N 2.78Å; V275-E278 PolarHBondContact O-N 2.75Å; E278-R280 VanDerWaalsContact C-N 3.32Å; E278-R280 PolarHBondContact O-N 3.41Å; E278-K281 WeakPolarHBondContact O-CB 3.47Å; E278-K281 PolarHBondContact O-N 3.44Å; E278-K281 VanDerWaalsContact O-N 3.11Å; E278-K281 IonicContact OE1-NZ 3.48Å; E278-K281 PolarHBondContact OE1-NZ 3.39Å; E278-V282 WeakPolarHBondContact O-CG2 3.12Å; E278-V282 PolarHBondContact O-N 2.89Å
279Q81.3Confident78.5Confident96 Ų9679.5 Ų79.545%0.44940%0.401SS..Hα-helixtrans-59.7-41.5176.5-73175.7000112.2V275 K281 V282 Q283V275-Q279 HydrophobicContact CG1-CG 4.36Å; V275-Q279 WeakPolarHBondContact O-CB 3.41Å; V275-Q279 VanDerWaalsContact O-CG 3.29Å; V275-Q279 WeakPolarHBondContact O-CG 3.3Å; V275-Q279 PolarHBondContact O-N 3.17Å; Q279-K281 PolarHBondContact O-N 2.93Å; Q279-V282 PolarHBondContact O-N 3.4Å; Q279-Q283 WeakPolarHBondContact O-CG 3.32Å; Q279-Q283 PolarHBondContact O-N 3.14Å
280R82.7Confident76.7Confident156 Ų15678.2 Ų78.259%0.58939%0.392SS*.Hα-helixtrans-61.4-42.5174-79.2178.4-77.6160.2-7112A276 E277 E278 V282 Q283 A284A276-R280 WeakPolarHBondContact O-CB 3.41Å; A276-R280 WeakPolarHBondContact O-CG 3.39Å; A276-R280 PolarHBondContact O-N 3.26Å; A276-R280 VanDerWaalsContact O-N 3.15Å; A276-R280 PolarHBondContact O-NE 3.09Å; E277-R280 PolarHBondContact O-N 3.45Å; E278-R280 VanDerWaalsContact C-N 3.32Å; E278-R280 PolarHBondContact O-N 3.41Å; R280-V282 VanDerWaalsContact C-N 3.34Å; R280-V282 PolarHBondContact O-N 3.42Å; R280-Q283 PolarHBondContact O-N 3.24Å; R280-A284 WeakPolarHBondContact O-CB 3.45Å; R280-A284 PolarHBondContact O-N 3.21Å
281K80.2Confident74.8Confident61 Ų6180 Ų8027%0.26541%0.412SS..Hα-helixtrans-61.6-40.9176-71.2171.2-172.7162.10111.8E277 E278 Q279 R285E277-K281 WeakPolarHBondContact O-CG 3.44Å; E277-K281 PolarHBondContact O-N 3.42Å; E277-K281 WeakPolarHBondContact OE1-CE 3.37Å; E277-K281 IonicContact OE1-NZ 2.86Å; E277-K281 PolarHBondContact OE1-NZ 3.41Å; E278-K281 WeakPolarHBondContact O-CB 3.47Å; E278-K281 PolarHBondContact O-N 3.44Å; E278-K281 VanDerWaalsContact O-N 3.11Å; E278-K281 IonicContact OE1-NZ 3.48Å; E278-K281 PolarHBondContact OE1-NZ 3.39Å; Q279-K281 PolarHBondContact O-N 2.93Å; K281-R285 WeakPolarHBondContact O-CB 3.42Å; K281-R285 VanDerWaalsContact O-CG 3.3Å; K281-R285 WeakPolarHBondContact O-CG 3.18Å; K281-R285 PolarHBondContact O-N 3.47Å
282V76.3Confident72.4Confident60 Ų6083.3 Ų83.336%0.36445%0.446SS..Hα-helixtrans-63.9-47.3177.2179.30000110.9P65 E278 Q279 R280 A284 R285 A286P65-V282 HydrophobicContact CG-CG2 3.74Å; E278-V282 WeakPolarHBondContact O-CG2 3.12Å; E278-V282 PolarHBondContact O-N 2.89Å; Q279-V282 PolarHBondContact O-N 3.4Å; R280-V282 VanDerWaalsContact C-N 3.34Å; R280-V282 PolarHBondContact O-N 3.42Å; V282-A284 PolarHBondContact O-N 2.98Å; V282-R285 PolarHBondContact O-N 3.12Å; V282-A286 PolarHBondContact O-N 2.99Å
283Q75.4Confident70.6Confident118 Ų11885.1 Ų85.155%0.55146%0.458SS*.Hα-helixtrans-61.7-45.2177.8-69.9174.86.400111.8Q279 R280 R285 A286 H287Q279-Q283 WeakPolarHBondContact O-CG 3.32Å; Q279-Q283 PolarHBondContact O-N 3.14Å; R280-Q283 PolarHBondContact O-N 3.24Å; Q283-R285 VanDerWaalsContact C-N 3.3Å; Q283-R285 PolarHBondContact O-N 3.41Å; Q283-A286 WeakPolarHBondContact O-CB 3.17Å; Q283-A286 PolarHBondContact O-N 2.86Å; Q283-A286 VanDerWaalsContact O-N 3.11Å; Q283-H287 PolarHBondContact O-N 3.47Å; Q283-H287 VanDerWaalsContact O-N 3.09Å; Q283-H287 PolarHBondContact O-ND1 3.39Å
284A74.6Confident68.4Low52 Ų5285.6 Ų85.643%0.4346%0.461SS..Hα-helixtrans-62-36.5177.400000112.7R280 V282 H287 R288R280-A284 WeakPolarHBondContact O-CB 3.45Å; R280-A284 PolarHBondContact O-N 3.21Å; V282-A284 PolarHBondContact O-N 2.98Å; A284-H287 PolarHBondContact O-N 2.75Å; A284-R288 PolarHBondContact O-N 2.79Å; A284-R288 VanDerWaalsContact O-N 3.13Å
285R70.1Confident66Low109 Ų10991.5 Ų91.541%0.41150%0.501SS..Hα-helixtrans-67.1-34.8174.3-76175.2179.1-172.11.6112.4K281 V282 Q283 K289K281-R285 WeakPolarHBondContact O-CB 3.42Å; K281-R285 VanDerWaalsContact O-CG 3.3Å; K281-R285 WeakPolarHBondContact O-CG 3.18Å; K281-R285 PolarHBondContact O-N 3.47Å; V282-R285 PolarHBondContact O-N 3.12Å; Q283-R285 VanDerWaalsContact C-N 3.3Å; Q283-R285 PolarHBondContact O-N 3.41Å; R285-K289 PolarHBondContact O-N 3.4Å
286A67.3Low63.5Low58 Ų5895.9 Ų95.948%0.47954%0.538SS..Hα-helixtrans-65.8-45.1174.900000111.2V282 Q283 R288 K289 S290V282-A286 PolarHBondContact O-N 2.99Å; Q283-A286 WeakPolarHBondContact O-CB 3.17Å; Q283-A286 PolarHBondContact O-N 2.86Å; Q283-A286 VanDerWaalsContact O-N 3.11Å; A286-R288 PolarHBondContact O-N 3.12Å; A286-K289 PolarHBondContact O-N 3.25Å; A286-K289 VanDerWaalsContact O-N 3.13Å; A286-S290 PolarHBondContact O-N 3.25Å
287H64.3Low61.2Low130 Ų13098.6 Ų98.660%0.60256%0.56SS**Hα-helixtrans-64.8-34.9178.8-71.877.6000113.4Q283 A284 K289 S290 A291Q283-H287 PolarHBondContact O-N 3.47Å; Q283-H287 VanDerWaalsContact O-N 3.09Å; Q283-H287 PolarHBondContact O-ND1 3.39Å; A284-H287 PolarHBondContact O-N 2.75Å; H287-K289 VanDerWaalsContact C-N 3.3Å; H287-K289 PolarHBondContact O-N 3.21Å; H287-S290 PolarHBondContact O-N 3.13Å; H287-S290 PolarHBondContact O-OG 3.4Å; H287-A291 PolarHBondContact O-N 3.14Å; H287-A291 VanDerWaalsContact O-N 3.13Å
288R60.6Low58.9Low206 Ų206103.6 Ų103.678%0.77758%0.584SS**Hα-helixtrans-69.4-27.6174.5-72.9-176.9-177.5-175.10.6113.1A284 A286 G292A284-R288 PolarHBondContact O-N 2.79Å; A284-R288 VanDerWaalsContact O-N 3.13Å; A286-R288 PolarHBondContact O-N 3.12Å; R288-G292 PolarHBondContact O-N 3.43Å
289K57.7Low56.4Low157 Ų157112.8 Ų112.868%0.68362%0.624SS**Hα-helixtrans-76.6-29176.1-77.5-177.8177.7-1780112.8R285 A286 H287R285-K289 PolarHBondContact O-N 3.4Å; A286-K289 PolarHBondContact O-N 3.25Å; A286-K289 VanDerWaalsContact O-N 3.13Å; H287-K289 VanDerWaalsContact C-N 3.3Å; H287-K289 PolarHBondContact O-N 3.21Å
290S54.9Low54.5Low77 Ų77113.3 Ų113.354%0.53864%0.636SS.*Hα-helixtrans-76.8-38.417353.10000112.2A286 H287 G292A286-S290 PolarHBondContact O-N 3.25Å; H287-S290 PolarHBondContact O-N 3.13Å; H287-S290 PolarHBondContact O-OG 3.4Å; S290-G292 PolarHBondContact O-N 3.16Å
291A49.1Very low52.7Low73 Ų73112.4 Ų112.460%0.60365%0.648SS**Hα-helixtrans-74.7-20.5179.300000114.6H287 S293H287-A291 PolarHBondContact O-N 3.14Å; H287-A291 VanDerWaalsContact O-N 3.13Å; A291-S293 VanDerWaalsContact C-N 3.31Å; A291-S293 PolarHBondContact O-N 2.99Å
292G40.4Very low50.7Low69 Ų69118.6 Ų118.671%0.71168%0.678SS**THydrogen-bonded Turntrans-83.43.9179.600000115.4R288 S290R288-G292 PolarHBondContact O-N 3.43Å; S290-G292 PolarHBondContact O-N 3.16Å
293S44.2Very low49Very low94 Ų94119.5 Ų119.566%0.65769%0.691SS**THydrogen-bonded Turntrans-97.5-4.5-179.6-1700000114A291A291-S293 VanDerWaalsContact C-N 3.31Å; A291-S293 PolarHBondContact O-N 2.99Å
294D36.5Very low47.6Very low139 Ų139121.5 Ų121.574%0.74370%0.704SS**  trans-105.241.5-169-72.2-20.1000114.4
295C33Very low46.2Very low133 Ų133123.5 Ų123.590%0.89972%0.72SS**  trans-141.769.4167.2-90.80000111.9
296A32.5Very low45.4Very low102 Ų102123 Ų12384%0.84373%0.73SS**  trans-158.491151.700000108.9
297A36.9Very low45.1Very low93 Ų93123.4 Ų123.477%0.76973%0.728SS**  trans-91.8145.8166.600000107.2
298Q34.9Very low45Very low184 Ų184121.5 Ų121.586%0.8673%0.726SS**  cis-161.2149.727.1-66.7168.9-20.900110.5
299K31.4Very low45.3Very low201 Ų201115.3 Ų115.387%0.87472%0.719SS**  -179.3158.3125.4-102.7-175.9-175.8-175.40111.4
300P42.3Very low45.9Very low108 Ų108113.9 Ų113.970%0.70172%0.715SS**  -100.1159.7-121.24.816.1000116.1E302P300-E302 PolarHBondContact O-N 2.84Å
301T44.2Very low46.5Very low137 Ų137115.6 Ų115.684%0.8472%0.717SS**  trans-7.699.215148.50000117.8
302E37.9Very low47.9Very low191 Ų191118.7 Ų118.789%0.89372%0.717SS**  trans-156.30.8154.5-115.5169.2-158.100114.9P300P300-E302 PolarHBondContact O-N 2.84Å
303A40Very low49.9Very low78 Ų78121.7 Ų121.765%0.64572%0.716SS**  trans-97.77.6-165.200000117.1A305A303-A305 PolarHBondContact O-N 2.94Å
304I46.6Very low51.6Low160 Ų160125.7 Ų125.782%0.82172%0.717SS**THydrogen-bonded Turntrans-80.9-14.9-171-60.4177.3000113
305A45.9Very low53.8Low94 Ų94123.7 Ų123.778%0.77770%0.703SS**THydrogen-bonded Turntrans-86-12.5177.900000114.9A303A303-A305 PolarHBondContact O-N 2.94Å
306V53.4Low56.4Low100 Ų100121.9 Ų121.961%0.60668%0.681SS**SBendtrans-85.9-15.6-172.2179.40000113.6
307S60.3Low58.9Low65 Ų65119.7 Ų119.746%0.45566%0.663SS.*Hα-helixtrans-88.4-16.5-168.181.20000116.9L311S307-L311 WeakPolarHBondContact O-CB 3.06Å; S307-L311 WeakPolarHBondContact O-CD1 3.32Å; S307-L311 WeakPolarHBondContact O-CG 3.33Å; S307-L311 PolarHBondContact O-N 3.03Å
308V62.8Low61Low90 Ų90120 Ų12055%0.54565%0.651SS.*Hα-helixtrans-84.2-37.6-174.1-178.70000112.7K312V308-K312 WeakPolarHBondContact O-CG 3.45Å; V308-K312 PolarHBondContact O-N 3.35Å; V308-K312 VanDerWaalsContact O-N 3.14Å
309A66.6Low63.5Low76 Ų76117.8 Ų117.863%0.62864%0.635SS**Hα-helixtrans-72.2-39.9-17900000112K312 L313A309-K312 PolarHBondContact O-N 3.5Å; A309-L313 PolarHBondContact O-N 2.99Å
310E70.1Confident66.2Low128 Ų128112.7 Ų112.760%0.59862%0.617SS**Hα-helixtrans-68.8-36.4177.8-162.1176.4-178.100111.7L313 R314E310-L313 PolarHBondContact O-N 3.44Å; E310-R314 WeakPolarHBondContact O-CB 3.09Å; E310-R314 PolarHBondContact O-N 3.27Å
311L66.6Low68.3Low112 Ų112115.9 Ų115.959%0.58662%0.615SS**Hα-helixtrans-64.7-42.1173-75.7172.8000112.3S307 R314 E315S307-L311 WeakPolarHBondContact O-CB 3.06Å; S307-L311 WeakPolarHBondContact O-CD1 3.32Å; S307-L311 WeakPolarHBondContact O-CG 3.33Å; S307-L311 PolarHBondContact O-N 3.03Å; L311-R314 PolarHBondContact O-N 2.9Å; L311-E315 WeakPolarHBondContact O-CB 3.17Å; L311-E315 PolarHBondContact O-N 2.83Å
312K78.8Confident70.2Confident138 Ų138115.8 Ų115.860%0.661%0.605SS**Hα-helixtrans-63.7-40.8175.5-76.3-179.5178.1-1770112.4V308 A309 R314 E315 Q316V308-K312 WeakPolarHBondContact O-CG 3.45Å; V308-K312 PolarHBondContact O-N 3.35Å; V308-K312 VanDerWaalsContact O-N 3.14Å; A309-K312 PolarHBondContact O-N 3.5Å; K312-R314 VanDerWaalsContact C-N 3.31Å; K312-R314 PolarHBondContact O-N 3.36Å; K312-E315 PolarHBondContact O-N 2.8Å; K312-Q316 PolarHBondContact O-N 3.33Å
313L83.5Confident72.6Confident133 Ų133111.6 Ų111.670%0.69659%0.586SS**Hα-helixtrans-65.6-37.8177.4-158.5115.3000111.4A309 E310 Q316 A317A309-L313 PolarHBondContact O-N 2.99Å; E310-L313 PolarHBondContact O-N 3.44Å; L313-Q316 PolarHBondContact O-N 2.85Å; L313-A317 WeakPolarHBondContact O-CB 3.34Å; L313-A317 PolarHBondContact O-N 3.36Å
314R79.4Confident74.8Confident178 Ų178110.8 Ų110.867%0.67258%0.579SS**Hα-helixtrans-71.2-36.5176.7-163.5168.2-174.8157.6-0.4112.6E310 L311 K312 A317 L318E310-R314 WeakPolarHBondContact O-CB 3.09Å; E310-R314 PolarHBondContact O-N 3.27Å; L311-R314 PolarHBondContact O-N 2.9Å; K312-R314 VanDerWaalsContact C-N 3.31Å; K312-R314 PolarHBondContact O-N 3.36Å; R314-A317 PolarHBondContact O-N 3.37Å; R314-L318 VanDerWaalsContact O-CG 3.31Å; R314-L318 WeakPolarHBondContact O-CG 3.43Å; R314-L318 PolarHBondContact O-N 3.3Å
315E82.8Confident76.4Confident96 Ų96107.7 Ų107.745%0.44956%0.563SS.*Hα-helixtrans-64.4-43172.8-169.2-177170.300111.1L311 K312 L318 R319L311-E315 WeakPolarHBondContact O-CB 3.17Å; L311-E315 PolarHBondContact O-N 2.83Å; K312-E315 PolarHBondContact O-N 2.8Å; E315-L318 PolarHBondContact O-N 2.99Å; E315-R319 WeakPolarHBondContact O-CG 3.29Å; E315-R319 PolarHBondContact O-N 2.86Å; E315-R319 IonicContact OE1-CZ 3.26Å; E315-R319 IonicContact OE1-NE 2.78Å; E315-R319 IonicContact OE1-NH2 2.86Å; E315-R319 PolarHBondContact OE1-NH2 3.04Å
316Q86.4Confident78.3Confident96 Ų96109.7 Ų109.745%0.44956%0.555SS.*Hα-helixtrans-62.9-44.8175.3-167.963.336.500111.5K312 L313 L318 R319 D320K312-Q316 PolarHBondContact O-N 3.33Å; L313-Q316 PolarHBondContact O-N 2.85Å; Q316-L318 VanDerWaalsContact C-N 3.26Å; Q316-L318 PolarHBondContact O-N 3.48Å; Q316-R319 PolarHBondContact O-N 2.74Å; Q316-R319 VanDerWaalsContact O-N 3.15Å; Q316-D320 PolarHBondContact NE2-OD1 3.04Å; Q316-D320 VanDerWaalsContact O-CG 3.28Å; Q316-D320 PolarHBondContact O-N 3.3Å
317A85.9Confident80Confident55 Ų55107.9 Ų107.946%0.45554%0.541SS..Hα-helixtrans-62.7-31.1176.800000113.3L313 R314 R321L313-A317 WeakPolarHBondContact O-CB 3.34Å; L313-A317 PolarHBondContact O-N 3.36Å; R314-A317 PolarHBondContact O-N 3.37Å; A317-R321 WeakPolarHBondContact O-CB 3.29Å; A317-R321 PolarHBondContact O-N 3.48Å
318L80.4Confident81.2Confident100 Ų100112.5 Ų112.552%0.52455%0.549SS..Hα-helixtrans-70.7-43.1173.6-74.2169.4000111.5R314 E315 Q316 R321 E322R314-L318 VanDerWaalsContact O-CG 3.31Å; R314-L318 WeakPolarHBondContact O-CG 3.43Å; R314-L318 PolarHBondContact O-N 3.3Å; E315-L318 PolarHBondContact O-N 2.99Å; Q316-L318 VanDerWaalsContact C-N 3.26Å; Q316-L318 PolarHBondContact O-N 3.48Å; L318-R321 PolarHBondContact O-N 2.97Å; L318-E322 WeakPolarHBondContact O-CG 3.42Å; L318-E322 PolarHBondContact O-N 3.39Å
319R87Confident82Confident137 Ų137114 Ų11452%0.51755%0.55SS.*Hα-helixtrans-61.5-44.8176-71.8179.6179.7171.36.1112.3E315 Q316 R321 E322 Q323E315-R319 WeakPolarHBondContact O-CG 3.29Å; E315-R319 PolarHBondContact O-N 2.86Å; E315-R319 IonicContact OE1-CZ 3.26Å; E315-R319 IonicContact OE1-NE 2.78Å; E315-R319 IonicContact OE1-NH2 2.86Å; E315-R319 PolarHBondContact OE1-NH2 3.04Å; Q316-R319 PolarHBondContact O-N 2.74Å; Q316-R319 VanDerWaalsContact O-N 3.15Å; R319-R321 VanDerWaalsContact C-N 3.26Å; R319-R321 PolarHBondContact O-N 3.04Å; R319-E322 PolarHBondContact O-N 3.15Å; R319-Q323 PolarHBondContact O-N 3.25Å
320D88.7Confident82.9Confident95 Ų95114.9 Ų114.951%0.50854%0.541SS..Hα-helixtrans-63.6-36.1178.3-63.3-16.4000111.1Q316 A324Q316-D320 PolarHBondContact NE2-OD1 3.04Å; Q316-D320 VanDerWaalsContact O-CG 3.28Å; Q316-D320 PolarHBondContact O-N 3.3Å; D320-A324 WeakPolarHBondContact O-CB 3.29Å; D320-A324 PolarHBondContact O-N 2.8Å
321R85.9Confident83.7Confident174 Ų174117.5 Ų117.566%0.65755%0.546SS*.Hα-helixtrans-70.8-39176.5-174.8174.9179.9153.40.8112.8A317 L318 R319 Q323 A324 L325A317-R321 WeakPolarHBondContact O-CB 3.29Å; A317-R321 PolarHBondContact O-N 3.48Å; L318-R321 PolarHBondContact O-N 2.97Å; R319-R321 VanDerWaalsContact C-N 3.26Å; R319-R321 PolarHBondContact O-N 3.04Å; R321-Q323 VanDerWaalsContact C-N 3.35Å; R321-A324 PolarHBondContact O-N 3.37Å; R321-L325 HydrophobicContact CG-CD1 4.47Å; R321-L325 WeakPolarHBondContact O-CG 3.42Å; R321-L325 PolarHBondContact O-N 3.21Å
322E83.9Confident84.2Confident135 Ų135116.8 Ų116.863%0.63154%0.542SS*.Hα-helixtrans-62.3-43.7173.7-77.1177.5173.900111.1L318 R319 A324 L325 K326L318-E322 WeakPolarHBondContact O-CG 3.42Å; L318-E322 PolarHBondContact O-N 3.39Å; R319-E322 PolarHBondContact O-N 3.15Å; E322-A324 PolarHBondContact O-N 3.36Å; E322-L325 PolarHBondContact O-N 3.46Å; E322-K326 PolarHBondContact O-N 2.91Å
323Q88.6Confident84.3Confident104 Ų104115.2 Ų115.249%0.48654%0.537SS..Hα-helixtrans-62.2-44.6175.7-170.861.141.500111.6R319 R321 L325 K326 D327R319-Q323 PolarHBondContact O-N 3.25Å; R321-Q323 VanDerWaalsContact C-N 3.35Å; Q323-L325 VanDerWaalsContact C-N 3.28Å; Q323-L325 PolarHBondContact O-N 3.41Å; Q323-K326 PolarHBondContact O-N 2.96Å; Q323-D327 PolarHBondContact NE2-OD1 3.23Å; Q323-D327 PolarHBondContact O-N 3.41Å
324A87.4Confident84.5Confident60 Ų60114 Ų11450%0.49653%0.526SS..Hα-helixtrans-63.2-32.7177.400000113.2D320 R321 E322 R328D320-A324 WeakPolarHBondContact O-CB 3.29Å; D320-A324 PolarHBondContact O-N 2.8Å; R321-A324 PolarHBondContact O-N 3.37Å; E322-A324 PolarHBondContact O-N 3.36Å; A324-R328 WeakPolarHBondContact O-CB 3.44Å; A324-R328 PolarHBondContact O-N 2.82Å
325L80Confident84.7Confident95 Ų95113.3 Ų113.350%0.49752%0.523SS..Hα-helixtrans-71.4-42.8174.8-75.3171.4000111.6R321 E322 Q323 R328 E329R321-L325 HydrophobicContact CG-CD1 4.47Å; R321-L325 WeakPolarHBondContact O-CG 3.42Å; R321-L325 PolarHBondContact O-N 3.21Å; E322-L325 PolarHBondContact O-N 3.46Å; Q323-L325 VanDerWaalsContact C-N 3.28Å; Q323-L325 PolarHBondContact O-N 3.41Å; L325-R328 WeakPolarHBondContact O-CB 3.41Å; L325-R328 PolarHBondContact O-N 2.76Å; L325-R328 VanDerWaalsContact O-N 3.15Å; L325-E329 PolarHBondContact O-N 3.31Å
326K86.3Confident84.4Confident136 Ų136115.3 Ų115.359%0.59153%0.532SS*.Hα-helixtrans-61.3-44.9176.8-169.2174.9-177179.90111.9E322 Q323 R328 E329 E330E322-K326 PolarHBondContact O-N 2.91Å; Q323-K326 PolarHBondContact O-N 2.96Å; K326-R328 VanDerWaalsContact C-N 3.25Å; K326-R328 PolarHBondContact O-N 3Å; K326-E329 PolarHBondContact O-N 3.27Å; K326-E330 PolarHBondContact O-N 3.36Å
327D88.4Confident84.1Confident62 Ų62116.7 Ų116.733%0.33254%0.539SS..Hα-helixtrans-63.2-33.6175.9-68-1000112Q323 R331Q323-D327 PolarHBondContact NE2-OD1 3.23Å; Q323-D327 PolarHBondContact O-N 3.41Å; D327-R331 VanDerWaalsContact O-CG 3.28Å; D327-R331 WeakPolarHBondContact O-CG 3.31Å; D327-R331 PolarHBondContact O-N 3.25Å
328R84.9Confident84.1Confident163 Ų163120.5 Ų120.562%0.61555%0.547SS*.Hα-helixtrans-72.2-40.3176.7-178.4179.3175.8178.4-0.5111.8A324 L325 K326 R331 L332A324-R328 WeakPolarHBondContact O-CB 3.44Å; A324-R328 PolarHBondContact O-N 2.82Å; L325-R328 WeakPolarHBondContact O-CB 3.41Å; L325-R328 PolarHBondContact O-N 2.76Å; L325-R328 VanDerWaalsContact O-N 3.15Å; K326-R328 VanDerWaalsContact C-N 3.25Å; K326-R328 PolarHBondContact O-N 3Å; R328-R331 PolarHBondContact O-N 3.33Å; R328-L332 HydrophobicContact CG-CD1 4.35Å; R328-L332 WeakPolarHBondContact O-CG 3.34Å; R328-L332 PolarHBondContact O-N 3Å
329E80.1Confident84Confident122 Ų122120.4 Ų120.457%0.5755%0.547SS*.Hα-helixtrans-61.2-47.5176-171168.9-153.300110.6L325 K326 R331 L332 E333L325-E329 PolarHBondContact O-N 3.31Å; K326-E329 PolarHBondContact O-N 3.27Å; E329-R331 VanDerWaalsContact C-N 3.29Å; E329-R331 PolarHBondContact O-N 3.21Å; E329-L332 WeakPolarHBondContact O-CB 3.49Å; E329-L332 PolarHBondContact O-N 3.49Å; E329-E333 PolarHBondContact O-N 3.01Å
330E86.4Confident83.9Confident94 Ų94117.6 Ų117.644%0.43955%0.547SS..Hα-helixtrans-61-37177.5-163.2-167.6153.800112.4K326 K334K326-E330 PolarHBondContact O-N 3.36Å; E330-K334 WeakPolarHBondContact O-CG 3.46Å; E330-K334 PolarHBondContact O-N 2.97Å; E330-K334 VanDerWaalsContact O-N 3.08Å; E330-K334 WeakPolarHBondContact OE1-CE 3.29Å; E330-K334 IonicContact OE1-NZ 2.71Å; E330-K334 PolarHBondContact OE1-NZ 3.33Å
331R86.9Confident83.8Confident183 Ų183118.1 Ų118.169%0.69155%0.549SS*.Hα-helixtrans-66.6-37174.1-73.2174.8-164-174.96112.4D327 R328 E329 R335D327-R331 VanDerWaalsContact O-CG 3.28Å; D327-R331 WeakPolarHBondContact O-CG 3.31Å; D327-R331 PolarHBondContact O-N 3.25Å; R328-R331 PolarHBondContact O-N 3.33Å; E329-R331 VanDerWaalsContact C-N 3.29Å; E329-R331 PolarHBondContact O-N 3.21Å; R331-R335 WeakPolarHBondContact O-CB 3.28Å; R331-R335 PolarHBondContact O-N 3.23Å; R331-R335 VanDerWaalsContact O-N 3.16Å
332L75.5Confident83.6Confident97 Ų97118.8 Ų118.851%0.50855%0.552SS.*Hα-helixtrans-70.8-42.2178.4-73171.6000110.8R328 E329 K334 R335 E336R328-L332 HydrophobicContact CG-CD1 4.35Å; R328-L332 WeakPolarHBondContact O-CG 3.34Å; R328-L332 PolarHBondContact O-N 3Å; E329-L332 WeakPolarHBondContact O-CB 3.49Å; E329-L332 PolarHBondContact O-N 3.49Å; L332-K334 PolarHBondContact O-N 3.15Å; L332-R335 PolarHBondContact O-N 2.9Å; L332-R335 VanDerWaalsContact O-N 3.16Å; L332-E336 WeakPolarHBondContact O-CB 3.32Å; L332-E336 PolarHBondContact O-N 3.35Å
333E82.3Confident83.4Confident104 Ų104118.6 Ų118.649%0.48655%0.551SS.*Hα-helixtrans-59.2-45.9174.7-73.7-175.2163.600111.9E329 R335 E336 Q337E329-E333 PolarHBondContact O-N 3.01Å; E333-R335 VanDerWaalsContact C-N 3.29Å; E333-R335 PolarHBondContact O-N 3.39Å; E333-E336 PolarHBondContact O-N 2.76Å; E333-Q337 WeakPolarHBondContact O-CG 3.14Å; E333-Q337 PolarHBondContact O-N 2.8Å
334K87.3Confident83.2Confident107 Ų107121.8 Ų121.847%0.46556%0.558SS.*Hα-helixtrans-58.6-42.8175.1-75.2174.2-173.8165.50111.7E330 L332 Q337 E338E330-K334 WeakPolarHBondContact O-CG 3.46Å; E330-K334 PolarHBondContact O-N 2.97Å; E330-K334 VanDerWaalsContact O-N 3.08Å; E330-K334 WeakPolarHBondContact OE1-CE 3.29Å; E330-K334 IonicContact OE1-NZ 2.71Å; E330-K334 PolarHBondContact OE1-NZ 3.33Å; L332-K334 PolarHBondContact O-N 3.15Å; K334-Q337 PolarHBondContact O-N 2.96Å; K334-E338 WeakPolarHBondContact O-CG 3.35Å; K334-E338 PolarHBondContact O-N 3.28Å
335R82.6Confident83.1Confident164 Ų164123.2 Ų123.262%0.61956%0.557SS**Hα-helixtrans-68.3-35.8178.8-168.8172.4-177.2175.20.3112.4R331 L332 E333 E338 L339R331-R335 WeakPolarHBondContact O-CB 3.28Å; R331-R335 PolarHBondContact O-N 3.23Å; R331-R335 VanDerWaalsContact O-N 3.16Å; L332-R335 PolarHBondContact O-N 2.9Å; L332-R335 VanDerWaalsContact O-N 3.16Å; E333-R335 VanDerWaalsContact C-N 3.29Å; E333-R335 PolarHBondContact O-N 3.39Å; R335-E338 PolarHBondContact O-N 3.3Å; R335-L339 VanDerWaalsContact O-CG 3.3Å; R335-L339 WeakPolarHBondContact O-CG 3.19Å; R335-L339 PolarHBondContact O-N 2.8Å
336E76.8Confident82.9Confident138 Ų138122 Ų12265%0.64556%0.557SS**Hα-helixtrans-66.7-42.6175.4-170.7174.1-178.800111.3L332 E333 E338 L339 C340L332-E336 WeakPolarHBondContact O-CB 3.32Å; L332-E336 PolarHBondContact O-N 3.35Å; E333-E336 PolarHBondContact O-N 2.76Å; E336-E338 PolarHBondContact O-N 3.3Å; E336-L339 PolarHBondContact O-N 2.84Å; E336-C340 WeakPolarHBondContact O-CB 3.3Å; E336-C340 PolarHBondContact O-N 2.94Å
337Q80.9Confident82.7Confident126 Ų126119.3 Ų119.359%0.58955%0.552SS**Hα-helixtrans-60-44.3173.2-70.6174.74.800111.8E333 K334 L339 C340 I341E333-Q337 WeakPolarHBondContact O-CG 3.14Å; E333-Q337 PolarHBondContact O-N 2.8Å; K334-Q337 PolarHBondContact O-N 2.96Å; Q337-L339 VanDerWaalsContact C-N 3.35Å; Q337-L339 PolarHBondContact O-N 3.02Å; Q337-C340 PolarHBondContact O-N 3.33Å; Q337-I341 VanDerWaalsContact O-CG1 3.32Å; Q337-I341 WeakPolarHBondContact O-CG1 3.33Å; Q337-I341 PolarHBondContact O-N 3.25Å
338E86.2Confident82.5Confident134 Ų134119.9 Ų119.963%0.62655%0.552SS**Hα-helixtrans-60.2-43.1175-75.7177.4-178.700112.4K334 R335 E336 I341 R342K334-E338 WeakPolarHBondContact O-CG 3.35Å; K334-E338 PolarHBondContact O-N 3.28Å; R335-E338 PolarHBondContact O-N 3.3Å; E336-E338 PolarHBondContact O-N 3.3Å; E338-I341 PolarHBondContact O-N 2.9Å; E338-R342 WeakPolarHBondContact O-CB 3.35Å; E338-R342 PolarHBondContact O-N 3.47Å
339L77Confident82.5Confident98 Ų98119.2 Ų119.251%0.51355%0.554SS.*Hα-helixtrans-65.7-41.8177.8-74172.3000111.7R335 E336 Q337 I341 R342 E343R335-L339 VanDerWaalsContact O-CG 3.3Å; R335-L339 WeakPolarHBondContact O-CG 3.19Å; R335-L339 PolarHBondContact O-N 2.8Å; E336-L339 PolarHBondContact O-N 2.84Å; Q337-L339 VanDerWaalsContact C-N 3.35Å; Q337-L339 PolarHBondContact O-N 3.02Å; L339-I341 PolarHBondContact O-N 3.07Å; L339-R342 WeakPolarHBondContact O-CB 3.41Å; L339-R342 PolarHBondContact O-N 3.16Å; L339-E343 WeakPolarHBondContact O-CB 3.44Å; L339-E343 PolarHBondContact O-N 3.38Å
340C85.2Confident82.4Confident79 Ų79118.2 Ų118.253%0.53455%0.552SS.*Hα-helixtrans-60.2-45.2176.1-176.50000111.6E336 Q337 R342 E343 R344E336-C340 WeakPolarHBondContact O-CB 3.3Å; E336-C340 PolarHBondContact O-N 2.94Å; Q337-C340 PolarHBondContact O-N 3.33Å; C340-R342 VanDerWaalsContact C-N 3.32Å; C340-R342 PolarHBondContact O-N 2.95Å; C340-E343 PolarHBondContact O-N 3.25Å; C340-R344 WeakPolarHBondContact O-CB 3.41Å; C340-R344 PolarHBondContact O-N 2.99Å
341I87.1Confident82.3Confident106 Ų106116.2 Ų116.254%0.54455%0.551SS.*Hα-helixtrans-61.5-43.7175.4-67.3165.9000110.4Q337 E338 L339 E343 R344 L345Q337-I341 VanDerWaalsContact O-CG1 3.32Å; Q337-I341 WeakPolarHBondContact O-CG1 3.33Å; Q337-I341 PolarHBondContact O-N 3.25Å; E338-I341 PolarHBondContact O-N 2.9Å; L339-I341 PolarHBondContact O-N 3.07Å; I341-E343 PolarHBondContact O-N 3.08Å; I341-R344 PolarHBondContact O-N 3.16Å; I341-L345 HydrophobicContact CG2-CD1 4.09Å; I341-L345 WeakPolarHBondContact O-CG 3.45Å; I341-L345 PolarHBondContact O-N 2.85Å
342R82.4Confident82.1Confident187 Ų187115.3 Ų115.371%0.70655%0.548SS*.Hα-helixtrans-64.8-40.2179.9-166.1178.3-164171.45.4112.3E338 L339 C340 L345 S346E338-R342 WeakPolarHBondContact O-CB 3.35Å; E338-R342 PolarHBondContact O-N 3.47Å; L339-R342 WeakPolarHBondContact O-CB 3.41Å; L339-R342 PolarHBondContact O-N 3.16Å; C340-R342 VanDerWaalsContact C-N 3.32Å; C340-R342 PolarHBondContact O-N 2.95Å; R342-L345 PolarHBondContact O-N 3.22Å; R342-S346 WeakPolarHBondContact O-CB 3.48Å; R342-S346 PolarHBondContact O-N 2.92Å
343E79.8Confident82.3Confident132 Ų132113 Ų11362%0.61754%0.543SS*.Hα-helixtrans-63.7-47.3176-174.8174.5-157.400110.7L339 C340 I341 L345 S346 T347L339-E343 WeakPolarHBondContact O-CB 3.44Å; L339-E343 PolarHBondContact O-N 3.38Å; C340-E343 PolarHBondContact O-N 3.25Å; I341-E343 PolarHBondContact O-N 3.08Å; E343-L345 VanDerWaalsContact C-N 3.33Å; E343-L345 PolarHBondContact O-N 3.37Å; E343-S346 CarbonylContact O-C 3.5Å; E343-S346 WeakPolarHBondContact O-CA 3.38Å; E343-S346 WeakPolarHBondContact O-CB 3.28Å; E343-S346 PolarHBondContact O-N 3.29Å; E343-T347 HydrophobicContact CG-CG2 4.49Å; E343-T347 WeakPolarHBondContact O-CG2 3.39Å; E343-T347 PolarHBondContact O-N 3.45Å; E343-T347 PolarHBondContact O-OG1 3Å
344R84Confident82.3Confident171 Ų171113.6 Ų113.665%0.64555%0.545SS*.Hα-helixtrans-58.5-42.7175.6-172.8176.6177.6167.73.4112.7C340 I341 S346 T347 E348C340-R344 WeakPolarHBondContact O-CB 3.41Å; C340-R344 PolarHBondContact O-N 2.99Å; I341-R344 PolarHBondContact O-N 3.16Å; R344-S346 VanDerWaalsContact C-N 3.28Å; R344-S346 PolarHBondContact O-N 3.46Å; R344-T347 WeakPolarHBondContact CA-OG1 3.47Å; R344-T347 PolarHBondContact O-N 3.41Å; R344-T347 PolarHBondContact O-OG1 3.47Å; R344-E348 IonicContact NE-OE1 2.84Å; R344-E348 WeakPolarHBondContact O-CB 3.46Å; R344-E348 WeakPolarHBondContact O-CG 3.36Å; R344-E348 PolarHBondContact O-N 3.23Å
345L84.3Confident82.1Confident89 Ų89111.5 Ų111.547%0.46655%0.545SS..Hα-helixtrans-65.6-32.9174.9-71.7171.3000112.2I341 R342 E343 K349I341-L345 HydrophobicContact CG2-CD1 4.09Å; I341-L345 WeakPolarHBondContact O-CG 3.45Å; I341-L345 PolarHBondContact O-N 2.85Å; R342-L345 PolarHBondContact O-N 3.22Å; E343-L345 VanDerWaalsContact C-N 3.33Å; E343-L345 PolarHBondContact O-N 3.37Å; L345-K349 VanDerWaalsContact O-CG 3.25Å; L345-K349 WeakPolarHBondContact O-CG 3.25Å; L345-K349 PolarHBondContact O-N 2.87Å
346S77.3Confident82.2Confident71 Ų71109.6 Ų109.650%0.49755%0.546SS..Hα-helixtrans-71-44.1176.3-167.80000111.6R342 E343 R344 K349 L350R342-S346 WeakPolarHBondContact O-CB 3.48Å; R342-S346 PolarHBondContact O-N 2.92Å; E343-S346 CarbonylContact O-C 3.5Å; E343-S346 WeakPolarHBondContact O-CA 3.38Å; E343-S346 WeakPolarHBondContact O-CB 3.28Å; E343-S346 PolarHBondContact O-N 3.29Å; R344-S346 VanDerWaalsContact C-N 3.28Å; R344-S346 PolarHBondContact O-N 3.46Å; S346-K349 PolarHBondContact O-N 3.38Å; S346-L350 WeakPolarHBondContact O-CB 3.3Å; S346-L350 PolarHBondContact O-N 2.86Å
347T81.6Confident82.4Confident78 Ų78108.4 Ų108.448%0.47954%0.543SS..Hα-helixtrans-65.6-40.1178.155.10000111.4E343 R344 K349 L350 A351E343-T347 HydrophobicContact CG-CG2 4.49Å; E343-T347 WeakPolarHBondContact O-CG2 3.39Å; E343-T347 PolarHBondContact O-N 3.45Å; E343-T347 PolarHBondContact O-OG1 3Å; R344-T347 WeakPolarHBondContact CA-OG1 3.47Å; R344-T347 PolarHBondContact O-N 3.41Å; R344-T347 PolarHBondContact O-OG1 3.47Å; T347-K349 PolarHBondContact O-N 3.49Å; T347-L350 PolarHBondContact O-N 3.44Å; T347-A351 WeakPolarHBondContact O-CB 3.42Å; T347-A351 PolarHBondContact O-N 2.81Å
348E84.8Confident82.4Confident74 Ų74108.8 Ų108.835%0.34654%0.543SS..Hα-helixtrans-62-41173.1-77.4-177.6-163.200112.6R344 L350 R352R344-E348 IonicContact NE-OE1 2.84Å; R344-E348 WeakPolarHBondContact O-CB 3.46Å; R344-E348 WeakPolarHBondContact O-CG 3.36Å; R344-E348 PolarHBondContact O-N 3.23Å; E348-L350 VanDerWaalsContact C-N 3.32Å; E348-R352 VanDerWaalsContact O-CG 3.29Å; E348-R352 WeakPolarHBondContact O-CG 3.27Å; E348-R352 PolarHBondContact O-N 2.87Å; E348-R352 IonicContact OE2-NH2 3.32Å
349K83.9Confident82Confident150 Ų150106 Ų10665%0.65253%0.533SS*.Hα-helixtrans-63.9-39.7175.5-77172.4-176.4177.70111.7L345 S346 T347 R352 A353L345-K349 VanDerWaalsContact O-CG 3.25Å; L345-K349 WeakPolarHBondContact O-CG 3.25Å; L345-K349 PolarHBondContact O-N 2.87Å; S346-K349 PolarHBondContact O-N 3.38Å; T347-K349 PolarHBondContact O-N 3.49Å; K349-R352 PolarHBondContact O-N 3.34Å; K349-A353 PolarHBondContact O-N 3.19Å
350L79.3Confident81.9Confident101 Ų101107.2 Ų107.253%0.52953%0.531SS..Hα-helixtrans-67.3-46.5178.8-161.6147.7000110.8S346 T347 E348 R352 A353 E354S346-L350 WeakPolarHBondContact O-CB 3.3Å; S346-L350 PolarHBondContact O-N 2.86Å; T347-L350 PolarHBondContact O-N 3.44Å; E348-L350 VanDerWaalsContact C-N 3.32Å; L350-R352 VanDerWaalsContact C-N 3.32Å; L350-R352 PolarHBondContact O-N 3.21Å; L350-A353 WeakPolarHBondContact O-CB 3.46Å; L350-A353 PolarHBondContact O-N 2.68Å; L350-A353 VanDerWaalsContact O-N 3.07Å; L350-E354 HydrophobicContact CD2-CG 4.09Å; L350-E354 VanDerWaalsContact CD2-OE1 3.25Å; L350-E354 WeakPolarHBondContact CD2-OE1 3.31Å; L350-E354 WeakPolarHBondContact O-CG 3.19Å; L350-E354 PolarHBondContact O-N 3.02Å
351A82.6Confident81.6Confident51 Ų51106.4 Ų106.442%0.42153%0.526SS..Hα-helixtrans-59.6-39.2175.200000112.8T347 E354 S355T347-A351 WeakPolarHBondContact O-CB 3.42Å; T347-A351 PolarHBondContact O-N 2.81Å; A351-E354 PolarHBondContact O-N 3.01Å; A351-S355 PolarHBondContact O-N 3.46Å
352R83.6Confident81Confident164 Ų164108.4 Ų108.462%0.61953%0.527SS*.Hα-helixtrans-63.8-42173.6-72.4178-158.4-162.57.4111.9E348 K349 L350 S355 L356E348-R352 VanDerWaalsContact O-CG 3.29Å; E348-R352 WeakPolarHBondContact O-CG 3.27Å; E348-R352 PolarHBondContact O-N 2.87Å; E348-R352 IonicContact OE2-NH2 3.32Å; K349-R352 PolarHBondContact O-N 3.34Å; L350-R352 VanDerWaalsContact C-N 3.32Å; L350-R352 PolarHBondContact O-N 3.21Å; R352-S355 PolarHBondContact O-N 3.39Å; R352-L356 WeakPolarHBondContact O-CG 3.43Å; R352-L356 PolarHBondContact O-N 3.37Å
353A79.2Confident80.6Confident48 Ų48104.6 Ų104.640%0.39752%0.52SS..Hα-helixtrans-64.3-42.8177.300000111.7K349 L350 S355 L356 L357K349-A353 PolarHBondContact O-N 3.19Å; L350-A353 WeakPolarHBondContact O-CB 3.46Å; L350-A353 PolarHBondContact O-N 2.68Å; L350-A353 VanDerWaalsContact O-N 3.07Å; A353-S355 PolarHBondContact O-N 3.49Å; A353-L356 PolarHBondContact O-N 2.99Å; A353-L357 WeakPolarHBondContact O-CG 3.26Å; A353-L357 PolarHBondContact O-N 2.98Å
354E82.9Confident80.3Confident117 Ų117102.7 Ų102.755%0.54751%0.511SS..Hα-helixtrans-61.3-43.5174.9-72.5179.6164.400112.1L350 A351 L356 L357 K358L350-E354 HydrophobicContact CD2-CG 4.09Å; L350-E354 VanDerWaalsContact CD2-OE1 3.25Å; L350-E354 WeakPolarHBondContact CD2-OE1 3.31Å; L350-E354 WeakPolarHBondContact O-CG 3.19Å; L350-E354 PolarHBondContact O-N 3.02Å; A351-E354 PolarHBondContact O-N 3.01Å; E354-L356 VanDerWaalsContact C-N 3.32Å; E354-L356 PolarHBondContact O-N 3.45Å; E354-L357 PolarHBondContact O-N 3.5Å; E354-K358 WeakPolarHBondContact O-CB 3.37Å; E354-K358 PolarHBondContact O-N 2.98Å
355S83.4Confident79.5Confident64 Ų64100.6 Ų100.645%0.44851%0.509SS..Hα-helixtrans-62.9-38.4176.3-173.90000112.2A351 R352 A353 K358 N359A351-S355 PolarHBondContact O-N 3.46Å; R352-S355 PolarHBondContact O-N 3.39Å; A353-S355 PolarHBondContact O-N 3.49Å; S355-K358 PolarHBondContact O-N 3.45Å; S355-N359 WeakPolarHBondContact O-CB 3.49Å; S355-N359 VanDerWaalsContact O-CG 3.26Å; S355-N359 PolarHBondContact O-N 2.83Å; S355-N359 PolarHBondContact O-ND2 2.98Å
356L84.7Confident78.6Confident123 Ų123103.1 Ų103.164%0.64452%0.516SS*.Hα-helixtrans-66-43.7176.3-76.6170.6000111.6R352 A353 E354 K358 N359 Y360R352-L356 WeakPolarHBondContact O-CG 3.43Å; R352-L356 PolarHBondContact O-N 3.37Å; A353-L356 PolarHBondContact O-N 2.99Å; E354-L356 VanDerWaalsContact C-N 3.32Å; E354-L356 PolarHBondContact O-N 3.45Å; L356-K358 VanDerWaalsContact C-N 3.35Å; L356-K358 PolarHBondContact O-N 3.37Å; L356-N359 PolarHBondContact O-N 2.98Å; L356-Y360 WeakPolarHBondContact O-CB 3.33Å; L356-Y360 PolarHBondContact O-N 2.99Å
357L80.1Confident77.6Confident114 Ų114105 Ų10560%0.59752%0.52SS*.Hα-helixtrans-61.3-43.9175.8-74.4169.1000111.4A353 E354 N359 Y360 S361A353-L357 WeakPolarHBondContact O-CG 3.26Å; A353-L357 PolarHBondContact O-N 2.98Å; E354-L357 PolarHBondContact O-N 3.5Å; L357-N359 VanDerWaalsContact C-N 3.33Å; L357-N359 PolarHBondContact O-N 3.42Å; L357-Y360 PolarHBondContact O-N 2.9Å; L357-S361 PolarHBondContact O-N 2.84Å; L357-S361 PolarHBondContact O-OG 3.3Å
358K81.7Confident76.3Confident133 Ų133107.5 Ų107.558%0.57853%0.527SS*.Hα-helixtrans-62.7-39.3177.4-167173.9-174.5173.80112.5E354 S355 L356 R362E354-K358 WeakPolarHBondContact O-CB 3.37Å; E354-K358 PolarHBondContact O-N 2.98Å; S355-K358 PolarHBondContact O-N 3.45Å; L356-K358 VanDerWaalsContact C-N 3.35Å; L356-K358 PolarHBondContact O-N 3.37Å; K358-R362 PolarHBondContact O-N 3.45Å; K358-R362 VanDerWaalsContact O-N 3.08Å
359N77.2Confident74.9Confident77 Ų77108.8 Ų108.841%0.41254%0.54SS..Hα-helixtrans-68.3-39.6175.4-73.5-17.2000111.9S355 L356 L357 R362 L363S355-N359 WeakPolarHBondContact O-CB 3.49Å; S355-N359 VanDerWaalsContact O-CG 3.26Å; S355-N359 PolarHBondContact O-N 2.83Å; S355-N359 PolarHBondContact O-ND2 2.98Å; L356-N359 PolarHBondContact O-N 2.98Å; L357-N359 VanDerWaalsContact C-N 3.33Å; L357-N359 PolarHBondContact O-N 3.42Å; N359-R362 PolarHBondContact O-N 2.97Å; N359-L363 PolarHBondContact O-N 3.45Å
360Y75.6Confident73.5Confident123 Ų123108.1 Ų108.148%0.48254%0.543SS..Hα-helixtrans-63.5-44.7174.8-176.8-101.3000112L356 L357 R362 L363 Q364L356-Y360 WeakPolarHBondContact O-CB 3.33Å; L356-Y360 PolarHBondContact O-N 2.99Å; L357-Y360 PolarHBondContact O-N 2.9Å; Y360-R362 VanDerWaalsContact C-N 3.31Å; Y360-R362 PolarHBondContact O-N 3.43Å; Y360-L363 PolarHBondContact O-N 2.97Å; Y360-L363 VanDerWaalsContact O-N 3.16Å; Y360-Q364 HydrophobicContact CD1-CG 4.5Å; Y360-Q364 HydrophobicContact CE1-CG 4.06Å; Y360-Q364 PolarHBondContact O-N 3.26Å; Y360-Q364 PolarHBondContact OH-NE2 3.46Å; Y360-Q364 VanDerWaalsContact OH-NE2 3.16Å
361S78.3Confident72.2Confident61 Ų61107 Ų10743%0.42755%0.547SS..Hα-helixtrans-60-38.8174-61.30000112.6L357 Q364 Q365L357-S361 PolarHBondContact O-N 2.84Å; L357-S361 PolarHBondContact O-OG 3.3Å; S361-Q364 PolarHBondContact O-N 2.88Å; S361-Q365 WeakPolarHBondContact O-CG 3.32Å; S361-Q365 PolarHBondContact O-N 3.24Å
362R74.5Confident70.4Confident149 Ų149114.7 Ų114.756%0.56257%0.567SS**Hα-helixtrans-65.7-37.5174.9-82.2-179.6175.8-178.2-2.5112.9K358 N359 Y360 K366K358-R362 PolarHBondContact O-N 3.45Å; K358-R362 VanDerWaalsContact O-N 3.08Å; N359-R362 PolarHBondContact O-N 2.97Å; Y360-R362 VanDerWaalsContact C-N 3.31Å; Y360-R362 PolarHBondContact O-N 3.43Å; R362-K366 PolarHBondContact O-N 2.9Å
363L73.8Confident68.6Low106 Ų106110 Ų11056%0.55557%0.57SS**Hα-helixtrans-66.9-43.7175.6-77.3162.1000111N359 Y360 Q365 K366 D367N359-L363 PolarHBondContact O-N 3.45Å; Y360-L363 PolarHBondContact O-N 2.97Å; Y360-L363 VanDerWaalsContact O-N 3.16Å; L363-Q365 VanDerWaalsContact C-N 3.34Å; L363-Q365 PolarHBondContact O-N 2.9Å; L363-K366 PolarHBondContact O-N 3.42Å; L363-K366 VanDerWaalsContact O-N 3.15Å; L363-D367 PolarHBondContact O-N 3.08Å
364Q72.6Confident66.9Low92 Ų92116.2 Ų116.243%0.4359%0.588SS.*Hα-helixtrans-60.2-41174.2-77.9-170-21.200112.9Y360 S361 K366 D367 Q368Y360-Q364 HydrophobicContact CD1-CG 4.5Å; Y360-Q364 HydrophobicContact CE1-CG 4.06Å; Y360-Q364 PolarHBondContact O-N 3.26Å; Y360-Q364 PolarHBondContact OH-NE2 3.46Å; Y360-Q364 VanDerWaalsContact OH-NE2 3.16Å; S361-Q364 PolarHBondContact O-N 2.88Å; Q364-K366 VanDerWaalsContact C-N 3.35Å; Q364-D367 PolarHBondContact O-N 3.07Å; Q364-Q368 WeakPolarHBondContact O-CB 3.49Å; Q364-Q368 WeakPolarHBondContact O-CG 3.4Å; Q364-Q368 PolarHBondContact O-N 3.34Å
365Q68.3Low64.8Low128 Ų128118.3 Ų118.360%0.59860%0.603SS**Hα-helixtrans-65.2-38.2175.2-78.3-179.7-1900112.2S361 L363 Q368 T369S361-Q365 WeakPolarHBondContact O-CG 3.32Å; S361-Q365 PolarHBondContact O-N 3.24Å; L363-Q365 VanDerWaalsContact C-N 3.34Å; L363-Q365 PolarHBondContact O-N 2.9Å; Q365-Q368 PolarHBondContact O-N 3.41Å; Q365-T369 PolarHBondContact O-N 2.89Å; Q365-T369 PolarHBondContact O-OG1 3.37Å
366K64.5Low62.5Low141 Ų141123.4 Ų123.461%0.61362%0.624SS**Hα-helixtrans-65.8-43.2175-81.6-173.7173.8-172.40112.4R362 L363 Q364 Q368 T369 L370R362-K366 PolarHBondContact O-N 2.9Å; L363-K366 PolarHBondContact O-N 3.42Å; L363-K366 VanDerWaalsContact O-N 3.15Å; Q364-K366 VanDerWaalsContact C-N 3.35Å; K366-Q368 VanDerWaalsContact C-N 3.32Å; K366-Q368 PolarHBondContact O-N 3.43Å; K366-T369 VanDerWaalsContact CA-OG1 3.31Å; K366-T369 WeakPolarHBondContact CA-OG1 3.35Å; K366-T369 PolarHBondContact O-N 3.49Å; K366-T369 PolarHBondContact O-OG1 3.37Å; K366-L370 PolarHBondContact O-N 3.08Å
367D57.5Low60.1Low110 Ų110124.9 Ų124.959%0.58863%0.633SS**Hα-helixtrans-63.9-36.8175.3-80.3-18000111.7L363 Q364 L370 A371L363-D367 PolarHBondContact O-N 3.08Å; Q364-D367 PolarHBondContact O-N 3.07Å; D367-L370 PolarHBondContact O-N 3.19Å; D367-A371 WeakPolarHBondContact O-CB 3.41Å; D367-A371 PolarHBondContact O-N 3.5Å
368Q54.3Low58.2Low131 Ų131125 Ų12561%0.61264%0.64SS**Hα-helixtrans-67-38.1172.8-81.1177.6-14.800112.8Q364 Q365 K366 A371 Y372Q364-Q368 WeakPolarHBondContact O-CB 3.49Å; Q364-Q368 WeakPolarHBondContact O-CG 3.4Å; Q364-Q368 PolarHBondContact O-N 3.34Å; Q365-Q368 PolarHBondContact O-N 3.41Å; K366-Q368 VanDerWaalsContact C-N 3.32Å; K366-Q368 PolarHBondContact O-N 3.43Å; Q368-A371 PolarHBondContact O-N 3.32Å; Q368-Y372 PolarHBondContact O-N 2.92Å; Q368-Y372 VanDerWaalsContact O-N 3.17Å
369T55.6Low55.9Low101 Ų101127.1 Ų127.162%0.6265%0.652SS**Hα-helixtrans-71-30.2174.448.80000113.4Q365 K366Q365-T369 PolarHBondContact O-N 2.89Å; Q365-T369 PolarHBondContact O-OG1 3.37Å; K366-T369 VanDerWaalsContact CA-OG1 3.31Å; K366-T369 WeakPolarHBondContact CA-OG1 3.35Å; K366-T369 PolarHBondContact O-N 3.49Å; K366-T369 PolarHBondContact O-OG1 3.37Å
370L54.8Low53.6Low137 Ų137131.3 Ų131.372%0.71767%0.674SS**Hα-helixtrans-74.2-29.1172.3-89.3146.9000112.3K366 D367K366-L370 PolarHBondContact O-N 3.08Å; D367-L370 PolarHBondContact O-N 3.19Å
371A52Low51.4Low76 Ų76132.3 Ų132.363%0.62869%0.687SS**Hα-helixtrans-75.2-24.6174.400000113.6D367 Q368D367-A371 WeakPolarHBondContact O-CB 3.41Å; D367-A371 PolarHBondContact O-N 3.5Å; Q368-A371 PolarHBondContact O-N 3.32Å
372Y44.7Very low49.2Very low214 Ų214134.6 Ų134.684%0.83970%0.703SS**THydrogen-bonded Turntrans-976.5178.6-95.6-85.4000114.6Q368Q368-Y372 PolarHBondContact O-N 2.92Å; Q368-Y372 VanDerWaalsContact O-N 3.17Å
373G44.7Very low48Very low65 Ų65133.1 Ų133.167%0.6771%0.713SS**SBendtrans-93.95.4179.400000115.8
374K44Very low45.7Very low179 Ų179131.3 Ų131.378%0.77872%0.72SS**  trans-114.4100.9169.4-82.9-177.5175.2179.50107.7
375D38.7Very low43.8Very low161 Ų161136.7 Ų136.786%0.86174%0.742SS**  trans169.595140.4-80.8-19.6000108.9
376L35.4Very low42Very low170 Ų170139.9 Ų139.989%0.8975%0.754SS**  trans-136.7104.6155.1-82.3173.4000107.8
377D32.9Very low40.3Very low155 Ų155142.4 Ų142.483%0.82977%0.765SS**  trans35.7137.8159.1-66.9-39.3000123.8
378P41.8Very low38.9Very low115 Ų115143 Ų14375%0.74777%0.772SS**  trans-97.8133.9168.736.7-26.9000112.2
379E31.8Very low37.8Very low179 Ų179144.7 Ų144.784%0.83678%0.78SS**  trans159.9103145.2-83-115.1148.100109
380D30.7Very low36.4Very low164 Ų164149.2 Ų149.288%0.87779%0.791SS**  -160.6141.8125.7-133.9-18.8000111
381L28.5Very low35.4Very low145 Ų145147.3 Ų147.376%0.75980%0.795SS**  trans-85.6158.7-165.7-83.6139.8000114.2
382S31.7Very low34.2Very low109 Ų109147.3 Ų147.376%0.76280%0.802SS**  trans103.1154.6143.6-117.90000119.4
383P48.9Very low33.5Very low118 Ų118146.2 Ų146.277%0.76681%0.805SS**  -137163.3-92.437.2-18.3000116.1
384G26.5Very low32.7Very low67 Ų67148.8 Ų148.869%0.69181%0.813SS**  trans100.9118.9136.600000118.1
385K32.3Very low32.5Very low206 Ų206150 Ų15090%0.89682%0.818SS**  170.6122.991.8-90.1173.1-177.6173.20111.2
386K30Very low32.1Very low194 Ų194150.9 Ų150.984%0.84382%0.817SS**  trans9130.7140.8-63.3176.9174.2178.30118.3
387K29.7Very low31.9Very low195 Ų195149.7 Ų149.785%0.84881%0.811SS**  161.3100115.7-88.9174.6178.1-176.10108.9
388V27.3Very low32.3Very low123 Ų123151.6 Ų151.675%0.74582%0.815SS**  57.7107.586.4-163.40000114.7
389H31.2Very low32.1Very low166 Ų166154.9 Ų154.977%0.76982%0.821SS**  trans42.6144.2150.5-62.2-67.6000120.7
390F27Very low32.4Very low195 Ų195151.9 Ų151.986%0.85582%0.817SS**  -162.8172.850.3-122.9-86.5000111.5
391A33.4Very low33.2Very low98 Ų98149.2 Ų149.281%0.8182%0.817SS**  trans-39153.3-175.900000120.1
392G27.6Very low33.5Very low75 Ų75144.2 Ų144.277%0.77380%0.801SS**  trans176.5109.3162.300000111.7
393E30.4Very low34.1Very low191 Ų191144.4 Ų144.489%0.89380%0.8SS**  trans-58.2141173.7-62.5175.9135.600112.1
394S27.9Very low33.6Very low120 Ų120148.2 Ų148.284%0.83980%0.8SS**  trans-170.4111.1133.5-78.80000110.6
395K38.1Very low34.5Very low203 Ų203152.5 Ų152.588%0.88380%0.802SS**  trans3.9128156.2-62.5174.4177.5176.20117.9
396E31.1Very low35.1Very low180 Ų180146.8 Ų146.884%0.84178%0.781SS**  -171.8132.1107.1-102.8177.1175.200113.2
397N30.9Very low36Very low145 Ų145141.9 Ų141.978%0.77576%0.764SS**  trans56.585.9155.6-69.5-15.6000120.6
398Q41.8Very low36.9Very low195 Ų195139.5 Ų139.591%0.91176%0.757SS**  trans-83130.5138.2-71.6176.3-4.200109.2
399Q37.1Very low38.1Very low185 Ų185138 Ų13886%0.86475%0.745SS**  trans-126.6147.5157.5-95.3-162.9-14.300111.1
400P39Very low39.1Very low116 Ų116137.3 Ų137.375%0.75374%0.735SS**  trans-102.1153-146.98.314.1000112.3G402P400-G402 PolarHBondContact O-N 3.02Å
401A46Very low40.6Very low107 Ų107136.6 Ų136.688%0.88473%0.727SS**  trans-57.2108.1167.400000110.1
402G36.4Very low41.5Very low40 Ų40136.2 Ų136.241%0.41271%0.711SS.*  trans-106.5169-176.100000114.2P400 Y404P400-G402 PolarHBondContact O-N 3.02Å; G402-Y404 PolarHBondContact O-N 3.06Å
403P43.9Very low42.9Very low114 Ų114138.4 Ų138.474%0.7470%0.701SS**THydrogen-bonded Turntrans-67.18.4-168.930.7-38.9000115.7
404Y39.2Very low44.3Very low198 Ų198132.8 Ų132.878%0.77668%0.68SS**Hα-helixtrans-73.4-32.3177.8-108.4-96.2000112.6G402 M408G402-Y404 PolarHBondContact O-N 3.06Å; Y404-M408 WeakPolarHBondContact O-CB 3.49Å; Y404-M408 PolarHBondContact O-N 3.47Å
405Q44.3Very low45.7Very low157 Ų157129.6 Ų129.673%0.73466%0.661SS**Hα-helixtrans-69-39.6-178.3-137120.32.900111.8M408 L409Q405-M408 PolarHBondContact O-N 3.26Å; Q405-L409 WeakPolarHBondContact O-CB 3.33Å; Q405-L409 PolarHBondContact O-N 3.14Å
406D45.3Very low46.5Very low85 Ų85124.4 Ų124.446%0.45564%0.642SS.*Hα-helixtrans-69.9-38.9178.6-168.651.7000111.9M408 L409 R410D406-M408 VanDerWaalsContact C-N 3.33Å; D406-M408 PolarHBondContact O-N 2.89Å; D406-L409 PolarHBondContact O-N 3.41Å; D406-R410 WeakPolarHBondContact O-CG 3.45Å; D406-R410 PolarHBondContact O-N 3.22Å; D406-R410 IonicContact OD2-CZ 2.86Å; D406-R410 IonicContact OD2-NE 3.68Å; D406-R410 PolarHBondContact OD2-NE 3.48Å; D406-R410 IonicContact OD2-NH2 3.95Å
407L47.9Very low48Very low91 Ų91120.8 Ų120.848%0.47663%0.628SS.*Hα-helixtrans-65.3-38.2174.9-170.169.8000111.8R411L407-R411 WeakPolarHBondContact O-CB 3.46Å; L407-R411 WeakPolarHBondContact O-CG 3.49Å; L407-R411 PolarHBondContact O-N 3.25Å
408M49Very low49.5Very low145 Ų145122.1 Ų122.171%0.71462%0.622SS**Hα-helixtrans-69.4-39.4177.2-154.4176.3-172.200111.2Y404 Q405 D406 R411 L412Y404-M408 WeakPolarHBondContact O-CB 3.49Å; Y404-M408 PolarHBondContact O-N 3.47Å; Q405-M408 PolarHBondContact O-N 3.26Å; D406-M408 VanDerWaalsContact C-N 3.33Å; D406-M408 PolarHBondContact O-N 2.89Å; M408-R411 PolarHBondContact O-N 3.04Å; M408-L412 WeakPolarHBondContact O-CB 3.41Å; M408-L412 PolarHBondContact O-N 3.4Å
409L52.1Low50.3Low92 Ų92115.4 Ų115.448%0.48260%0.6SS.*Hα-helixtrans-63.9-43.9175.7-163.470.5000111.7Q405 D406 R411 L412 Q413Q405-L409 WeakPolarHBondContact O-CB 3.33Å; Q405-L409 PolarHBondContact O-N 3.14Å; D406-L409 PolarHBondContact O-N 3.41Å; L409-R411 PolarHBondContact O-N 2.97Å; L409-L412 WeakPolarHBondContact O-CB 3.4Å; L409-L412 PolarHBondContact O-N 3.03Å; L409-Q413 WeakPolarHBondContact O-CG 3.43Å; L409-Q413 PolarHBondContact O-N 3.49Å
410R53.3Low51.4Low151 Ų151112.4 Ų112.457%0.5759%0.586SS**Hα-helixtrans-64-38.2174.8-73.3-178.5-173-154.9-1112.7D406 Q413 T414D406-R410 WeakPolarHBondContact O-CG 3.45Å; D406-R410 PolarHBondContact O-N 3.22Å; D406-R410 IonicContact OD2-CZ 2.86Å; D406-R410 IonicContact OD2-NE 3.68Å; D406-R410 PolarHBondContact OD2-NE 3.48Å; D406-R410 IonicContact OD2-NH2 3.95Å; R410-Q413 PolarHBondContact O-N 2.95Å; R410-T414 WeakPolarHBondContact O-CB 3.48Å; R410-T414 PolarHBondContact O-N 2.9Å; R410-T414 PolarHBondContact O-OG1 2.91Å
411R57.1Low52.8Low181 Ų181113.1 Ų113.168%0.68358%0.578SS**Hα-helixtrans-65.2-40.5174-80.3179.9168.2-174.6-1.4111.6L407 M408 L409 T414 A415L407-R411 WeakPolarHBondContact O-CB 3.46Å; L407-R411 WeakPolarHBondContact O-CG 3.49Å; L407-R411 PolarHBondContact O-N 3.25Å; M408-R411 PolarHBondContact O-N 3.04Å; L409-R411 PolarHBondContact O-N 2.97Å; R411-T414 PolarHBondContact O-N 3.36Å; R411-A415 WeakPolarHBondContact O-CB 3.45Å; R411-A415 PolarHBondContact O-N 2.88Å
412L53.3Low53.4Low90 Ų90113.7 Ų113.747%0.47157%0.565SS.*Hα-helixtrans-64.4-44.9176.3-160.884.2000111.3M408 L409 T414 A415 N416M408-L412 WeakPolarHBondContact O-CB 3.41Å; M408-L412 PolarHBondContact O-N 3.4Å; L409-L412 WeakPolarHBondContact O-CB 3.4Å; L409-L412 PolarHBondContact O-N 3.03Å; L412-T414 VanDerWaalsContact C-N 3.35Å; L412-T414 PolarHBondContact O-N 3.22Å; L412-A415 PolarHBondContact O-N 3.14Å; L412-N416 WeakPolarHBondContact O-CB 3.44Å; L412-N416 PolarHBondContact O-N 2.97Å
413Q57.5Low54.5Low121 Ų121114 Ų11457%0.56556%0.561SS**Hα-helixtrans-61.6-42.6175.4-75.9176.9-20.500111.8L409 R410 A415 N416 L417L409-Q413 WeakPolarHBondContact O-CG 3.43Å; L409-Q413 PolarHBondContact O-N 3.49Å; R410-Q413 PolarHBondContact O-N 2.95Å; Q413-A415 PolarHBondContact O-N 3.42Å; Q413-N416 PolarHBondContact O-N 3.16Å; Q413-L417 PolarHBondContact O-N 3.38Å
414T59.9Low55.4Low72 Ų72114.4 Ų114.444%0.44255%0.553SS.*Hα-helixtrans-66.9-37.4177.9-52.40000111.9R410 R411 L412 R418R410-T414 WeakPolarHBondContact O-CB 3.48Å; R410-T414 PolarHBondContact O-N 2.9Å; R410-T414 PolarHBondContact O-OG1 2.91Å; R411-T414 PolarHBondContact O-N 3.36Å; L412-T414 VanDerWaalsContact C-N 3.35Å; L412-T414 PolarHBondContact O-N 3.22Å; T414-R418 WeakPolarHBondContact O-CG 3.49Å; T414-R418 PolarHBondContact O-N 3.02Å; T414-R418 VanDerWaalsContact O-N 3.14Å
415A55.7Low56.8Low53 Ų53108.9 Ų108.944%0.43854%0.54SS..Hα-helixtrans-66.7-42.917500000111.7R411 L412 Q413 L417 R418 A419R411-A415 WeakPolarHBondContact O-CB 3.45Å; R411-A415 PolarHBondContact O-N 2.88Å; L412-A415 PolarHBondContact O-N 3.14Å; Q413-A415 PolarHBondContact O-N 3.42Å; A415-L417 PolarHBondContact O-N 3.31Å; A415-R418 PolarHBondContact O-N 3.31Å; A415-A419 WeakPolarHBondContact O-CB 3.47Å; A415-A419 PolarHBondContact O-N 3.44Å
416N56Low57.7Low94 Ų94107 Ų10750%0.50353%0.531SS..Hα-helixtrans-62.7-40.7175.3-82.5-14.3000112.1L412 Q413 R418 A419 Q420L412-N416 WeakPolarHBondContact O-CB 3.44Å; L412-N416 PolarHBondContact O-N 2.97Å; Q413-N416 PolarHBondContact O-N 3.16Å; N416-R418 VanDerWaalsContact C-N 3.3Å; N416-R418 PolarHBondContact O-N 3.01Å; N416-A419 PolarHBondContact O-N 2.97Å; N416-Q420 WeakPolarHBondContact O-CG 3.45Å; N416-Q420 PolarHBondContact O-N 3.45Å
417L61.9Low58.5Low104 Ų104109.4 Ų109.455%0.54554%0.537SS..Hα-helixtrans-63.9-36.6176.6-143.985.7000112Q413 A415 K421Q413-L417 PolarHBondContact O-N 3.38Å; A415-L417 PolarHBondContact O-N 3.31Å; L417-K421 WeakPolarHBondContact O-CG 3.4Å; L417-K421 PolarHBondContact O-N 2.91Å; L417-K421 VanDerWaalsContact O-N 3.08Å
418R63.1Low59.5Low173 Ų173109.4 Ų109.465%0.65354%0.537SS*.Hα-helixtrans-70.3-40.5174.7-73.6176.8-176.1176.91.5112T414 A415 N416 Q420 K421 L422T414-R418 WeakPolarHBondContact O-CG 3.49Å; T414-R418 PolarHBondContact O-N 3.02Å; T414-R418 VanDerWaalsContact O-N 3.14Å; A415-R418 PolarHBondContact O-N 3.31Å; N416-R418 VanDerWaalsContact C-N 3.3Å; N416-R418 PolarHBondContact O-N 3.01Å; R418-Q420 VanDerWaalsContact C-N 3.34Å; R418-K421 PolarHBondContact O-N 3.15Å; R418-L422 WeakPolarHBondContact O-CB 3.42Å; R418-L422 WeakPolarHBondContact O-CG 3.44Å; R418-L422 PolarHBondContact O-N 3.03Å
419A59.3Low59.8Low54 Ų54106.1 Ų106.145%0.44653%0.528SS..Hα-helixtrans-63.8-40.3175.900000111.6A415 N416 L422 S423A415-A419 WeakPolarHBondContact O-CB 3.47Å; A415-A419 PolarHBondContact O-N 3.44Å; N416-A419 PolarHBondContact O-N 2.97Å; A419-L422 PolarHBondContact O-N 3.41Å; A419-S423 WeakPolarHBondContact O-CB 3.41Å; A419-S423 PolarHBondContact O-N 3.41Å
420Q60.1Low59.8Low122 Ų122106.5 Ų106.557%0.5753%0.527SS*.Hα-helixtrans-63.5-46.1173.8-77.1178.3-1900111.9N416 R418 L422 S423 E424N416-Q420 WeakPolarHBondContact O-CG 3.45Å; N416-Q420 PolarHBondContact O-N 3.45Å; R418-Q420 VanDerWaalsContact C-N 3.34Å; Q420-L422 VanDerWaalsContact C-N 3.33Å; Q420-L422 PolarHBondContact O-N 2.93Å; Q420-S423 PolarHBondContact O-N 3.23Å; Q420-E424 WeakPolarHBondContact O-CG 3.4Å; Q420-E424 PolarHBondContact O-N 2.98Å
421K66.5Low59.6Low132 Ų132105.8 Ų105.857%0.57453%0.528SS*.Hα-helixtrans-61.5-39.4174.9-78-173.7176.4-173.40112.8L417 R418 E424 V425L417-K421 WeakPolarHBondContact O-CG 3.4Å; L417-K421 PolarHBondContact O-N 2.91Å; L417-K421 VanDerWaalsContact O-N 3.08Å; R418-K421 PolarHBondContact O-N 3.15Å; K421-E424 PolarHBondContact O-N 3.37Å; K421-V425 VanDerWaalsContact O-CG2 3.27Å; K421-V425 WeakPolarHBondContact O-CG2 3.5Å; K421-V425 PolarHBondContact O-N 3.41Å
422L59.3Low59.2Low118 Ų118103 Ų10362%0.61852%0.521SS*.Hα-helixtrans-66.6-40.3175.4-78.5164.5000111.6R418 A419 Q420 E424 V425 E426R418-L422 WeakPolarHBondContact O-CB 3.42Å; R418-L422 WeakPolarHBondContact O-CG 3.44Å; R418-L422 PolarHBondContact O-N 3.03Å; A419-L422 PolarHBondContact O-N 3.41Å; Q420-L422 VanDerWaalsContact C-N 3.33Å; Q420-L422 PolarHBondContact O-N 2.93Å; L422-E424 VanDerWaalsContact C-N 3.34Å; L422-E424 PolarHBondContact O-N 3.17Å; L422-V425 PolarHBondContact O-N 2.77Å; L422-E426 VanDerWaalsContact O-CB 3.31Å; L422-E426 WeakPolarHBondContact O-CB 3.41Å; L422-E426 PolarHBondContact O-N 3.15Å
423S59.4Low58.8Low48 Ų48101.5 Ų101.534%0.33652%0.518SS..Hα-helixtrans-64.5-36.8173.9-1750000112.2A419 Q420 E426 K427A419-S423 WeakPolarHBondContact O-CB 3.41Å; A419-S423 PolarHBondContact O-N 3.41Å; Q420-S423 PolarHBondContact O-N 3.23Å; S423-E426 PolarHBondContact O-N 2.75Å; S423-K427 WeakPolarHBondContact O-CB 3.25Å; S423-K427 VanDerWaalsContact O-CG 3.26Å; S423-K427 WeakPolarHBondContact O-CG 3.29Å; S423-K427 PolarHBondContact O-N 3.29Å
424E64.1Low58.2Low121 Ų121103.5 Ų103.557%0.56552%0.52SS*.Hα-helixtrans-66.8-43.1172.6-76.4-177.8166.500112Q420 K421 L422 E426 K427 I428Q420-E424 WeakPolarHBondContact O-CG 3.4Å; Q420-E424 PolarHBondContact O-N 2.98Å; K421-E424 PolarHBondContact O-N 3.37Å; L422-E424 VanDerWaalsContact C-N 3.34Å; L422-E424 PolarHBondContact O-N 3.17Å; E424-E426 VanDerWaalsContact C-N 3.3Å; E424-E426 PolarHBondContact O-N 3.48Å; E424-K427 PolarHBondContact O-N 2.91Å; E424-I428 WeakPolarHBondContact O-CB 3.45Å; E424-I428 WeakPolarHBondContact O-CD1 3.48Å; E424-I428 WeakPolarHBondContact O-CG1 3.47Å; E424-I428 PolarHBondContact O-N 3.49Å
425V67.6Low57.6Low82 Ų82106.6 Ų106.650%0.49753%0.53SS..Hα-helixtrans-62.2-40.5174.2170.60000110.7K421 L422 I428 C429K421-V425 VanDerWaalsContact O-CG2 3.27Å; K421-V425 WeakPolarHBondContact O-CG2 3.5Å; K421-V425 PolarHBondContact O-N 3.41Å; L422-V425 PolarHBondContact O-N 2.77Å; V425-I428 PolarHBondContact O-N 2.95Å; V425-C429 WeakPolarHBondContact O-CB 3.44Å; V425-C429 PolarHBondContact O-N 3.46Å; V425-C429 PolarHBondContact O-SG 2.89Å; V425-C429 VanDerWaalsContact O-SG 3.35Å
426E63.7Low57Low117 Ų117111 Ų11155%0.54754%0.544SS..Hα-helixtrans-67.2-40.2176.9-165.3174.4-16000111.5L422 S423 E424 C429 Q430L422-E426 VanDerWaalsContact O-CB 3.31Å; L422-E426 WeakPolarHBondContact O-CB 3.41Å; L422-E426 PolarHBondContact O-N 3.15Å; S423-E426 PolarHBondContact O-N 2.75Å; E424-E426 VanDerWaalsContact C-N 3.3Å; E424-E426 PolarHBondContact O-N 3.48Å; E426-C429 PolarHBondContact O-N 3.39Å; E426-Q430 WeakPolarHBondContact O-CB 3.49Å; E426-Q430 VanDerWaalsContact O-CG 3.3Å; E426-Q430 WeakPolarHBondContact O-CG 3.5Å; E426-Q430 PolarHBondContact O-N 3.49Å
427K61.6Low56.2Low136 Ų136111.9 Ų111.959%0.59155%0.549SS*.Hα-helixtrans-63.9-40171.3-77.1174.8-175.9178.30112.1S423 E424 Q430 F431S423-K427 WeakPolarHBondContact O-CB 3.25Å; S423-K427 VanDerWaalsContact O-CG 3.26Å; S423-K427 WeakPolarHBondContact O-CG 3.29Å; S423-K427 PolarHBondContact O-N 3.29Å; E424-K427 PolarHBondContact O-N 2.91Å; K427-Q430 PolarHBondContact O-N 3.24Å; K427-F431 WeakPolarHBondContact O-CB 3.49Å; K427-F431 PolarHBondContact O-N 2.91Å
428I68.3Low55.4Low92 Ų92110.2 Ų110.247%0.47256%0.556SS.*Hα-helixtrans-66.7-41.1175.7-70.2163.2000110.1E424 V425 F431 K432E424-I428 WeakPolarHBondContact O-CB 3.45Å; E424-I428 WeakPolarHBondContact O-CD1 3.48Å; E424-I428 WeakPolarHBondContact O-CG1 3.47Å; E424-I428 PolarHBondContact O-N 3.49Å; V425-I428 PolarHBondContact O-N 2.95Å; I428-F431 PolarHBondContact O-N 3.16Å; I428-K432 HydrophobicContact CG2-CD 4.2Å; I428-K432 VanDerWaalsContact O-CB 3.29Å; I428-K432 WeakPolarHBondContact O-CB 3.31Å; I428-K432 VanDerWaalsContact O-CG 3.28Å; I428-K432 WeakPolarHBondContact O-CG 3.42Å; I428-K432 PolarHBondContact O-N 2.95Å
429C55.7Low54.5Low76 Ų76107.9 Ų107.951%0.51456%0.555SS.*Hα-helixtrans-66.4-39.8174.6-76.90000111.8V425 E426 S433V425-C429 WeakPolarHBondContact O-CB 3.44Å; V425-C429 PolarHBondContact O-N 3.46Å; V425-C429 PolarHBondContact O-SG 2.89Å; V425-C429 VanDerWaalsContact O-SG 3.35Å; E426-C429 PolarHBondContact O-N 3.39Å; C429-S433 WeakPolarHBondContact O-CB 3.37Å; C429-S433 PolarHBondContact O-N 3.32Å
430Q53.3Low53.6Low100 Ų100120.2 Ų120.247%0.46759%0.591SS.*Hα-helixtrans-68.4-37.9173.8-77-178.64.600111.9E426 K427 S433 R434E426-Q430 WeakPolarHBondContact O-CB 3.49Å; E426-Q430 VanDerWaalsContact O-CG 3.3Å; E426-Q430 WeakPolarHBondContact O-CG 3.5Å; E426-Q430 PolarHBondContact O-N 3.49Å; K427-Q430 PolarHBondContact O-N 3.24Å; Q430-S433 PolarHBondContact O-N 3.03Å; Q430-R434 WeakPolarHBondContact O-CB 3.44Å; Q430-R434 VanDerWaalsContact O-CG 3.29Å; Q430-R434 WeakPolarHBondContact O-CG 3.36Å; Q430-R434 PolarHBondContact O-N 2.95Å
431F47.3Very low53.3Low135 Ų135120.2 Ų120.259%0.59259%0.592SS**Hα-helixtrans-70.3-40.9177.3-161.1-90.5000111.3K427 I428 R434 Q435K427-F431 WeakPolarHBondContact O-CB 3.49Å; K427-F431 PolarHBondContact O-N 2.91Å; I428-F431 PolarHBondContact O-N 3.16Å; F431-R434 PolarHBondContact O-N 3.34Å; F431-Q435 HydrophobicContact CD1-CG 4.25Å; F431-Q435 HydrophobicContact CE1-CG 4.12Å; F431-Q435 WeakPolarHBondContact O-CB 3.39Å; F431-Q435 PolarHBondContact O-N 2.94Å
432K49.8Very low52.6Low122 Ų122119.5 Ų119.553%0.5359%0.593SS.*Hα-helixtrans-63.9-41170.2-75.7-178.3177.2-174.70111.3I428 Q435 I436I428-K432 HydrophobicContact CG2-CD 4.2Å; I428-K432 VanDerWaalsContact O-CB 3.29Å; I428-K432 WeakPolarHBondContact O-CB 3.31Å; I428-K432 VanDerWaalsContact O-CG 3.28Å; I428-K432 WeakPolarHBondContact O-CG 3.42Å; I428-K432 PolarHBondContact O-N 2.95Å; K432-Q435 PolarHBondContact O-N 3.47Å; K432-I436 VanDerWaalsContact O-CB 3.29Å; K432-I436 WeakPolarHBondContact O-CB 3.48Å; K432-I436 VanDerWaalsContact O-CD1 3.32Å; K432-I436 WeakPolarHBondContact O-CD1 3.42Å; K432-I436 WeakPolarHBondContact O-CG1 3.4Å; K432-I436 PolarHBondContact O-N 3.46Å
433S43.8Very low52.3Low59 Ų59119.6 Ų119.641%0.41359%0.591SS.*Hα-helixtrans-61.9-42.4173.9-177.30000111.7C429 Q430 I436 L437C429-S433 WeakPolarHBondContact O-CB 3.37Å; C429-S433 PolarHBondContact O-N 3.32Å; Q430-S433 PolarHBondContact O-N 3.03Å; S433-I436 PolarHBondContact O-N 3.4Å; S433-L437 VanDerWaalsContact O-CB 3.29Å; S433-L437 WeakPolarHBondContact O-CB 3.38Å; S433-L437 WeakPolarHBondContact O-CD1 3.46Å; S433-L437 WeakPolarHBondContact O-CG 3.4Å; S433-L437 PolarHBondContact O-N 3.06Å
434R46.4Very low51.8Low163 Ų163123.8 Ų123.862%0.61561%0.606SS**Hα-helixtrans-68.2-37.8174.9-73.7178.8-174.9-159.62.5113.4Q430 F431 L437 G438Q430-R434 WeakPolarHBondContact O-CB 3.44Å; Q430-R434 VanDerWaalsContact O-CG 3.29Å; Q430-R434 WeakPolarHBondContact O-CG 3.36Å; Q430-R434 PolarHBondContact O-N 2.95Å; F431-R434 PolarHBondContact O-N 3.34Å; R434-L437 PolarHBondContact O-N 3.32Å; R434-G438 PolarHBondContact O-N 2.83Å; R434-G438 VanDerWaalsContact O-N 3.16Å
435Q45.9Very low51.1Low137 Ų137124 Ų12464%0.6461%0.609SS**Hα-helixtrans-66.3-38172.4-85.3-174.5-37.500112.2F431 K432 L437F431-Q435 HydrophobicContact CD1-CG 4.25Å; F431-Q435 HydrophobicContact CE1-CG 4.12Å; F431-Q435 WeakPolarHBondContact O-CB 3.39Å; F431-Q435 PolarHBondContact O-N 2.94Å; K432-Q435 PolarHBondContact O-N 3.47Å; Q435-L437 VanDerWaalsContact C-N 3.33Å
436I44.8Very low50Low145 Ų145126.8 Ų126.874%0.74462%0.616SS**Hα-helixtrans-70.3-30.7175.5-69.8164.4000111.1K432 S433K432-I436 VanDerWaalsContact O-CB 3.29Å; K432-I436 WeakPolarHBondContact O-CB 3.48Å; K432-I436 VanDerWaalsContact O-CD1 3.32Å; K432-I436 WeakPolarHBondContact O-CD1 3.42Å; K432-I436 WeakPolarHBondContact O-CG1 3.4Å; K432-I436 PolarHBondContact O-N 3.46Å; S433-I436 PolarHBondContact O-N 3.4Å
437L39.4Very low49Very low114 Ų114127.5 Ų127.560%0.59762%0.621SS**THydrogen-bonded Turntrans-87.9-2.3179.2-71167.5000114.7S433 R434 Q435 I439S433-L437 VanDerWaalsContact O-CB 3.29Å; S433-L437 WeakPolarHBondContact O-CB 3.38Å; S433-L437 WeakPolarHBondContact O-CD1 3.46Å; S433-L437 WeakPolarHBondContact O-CG 3.4Å; S433-L437 PolarHBondContact O-N 3.06Å; R434-L437 PolarHBondContact O-N 3.32Å; Q435-L437 VanDerWaalsContact C-N 3.33Å; L437-I439 HydrophobicContact CB-CD1 4.45Å; L437-I439 HydrophobicContact CB-CG1 4.4Å; L437-I439 PolarHBondContact O-N 3.04Å; L437-I439 VanDerWaalsContact O-N 3.13Å
438G44.9Very low48Very low68 Ų68126.8 Ų126.870%0.70162%0.623SS**THydrogen-bonded Turntrans60.523.2174.600000115.6R434R434-G438 PolarHBondContact O-N 2.83Å; R434-G438 VanDerWaalsContact O-N 3.16Å
439I43.8Very low46.3Very low124 Ų124129.8 Ų129.864%0.63664%0.636SS**  trans-91.5109.3177.2-56.7176.1000107.7L437L437-I439 HydrophobicContact CB-CD1 4.45Å; L437-I439 HydrophobicContact CB-CG1 4.4Å; L437-I439 PolarHBondContact O-N 3.04Å; L437-I439 VanDerWaalsContact O-N 3.13Å
440R40.8Very low45.5Very low314 Ų314134.6 Ų134.6100%1.18565%0.647SS**  trans-73.40161.2-89.4-171.1176.4-176.10110

Retrieved 440 of 440 residues in 109.4 ms (Link to these results)