A0A087YNL2_POEFO Loading...

Transporter

AlphaFold DB , UniProt , Accession A0A087YNL2, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 636 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	S	31.5	Very low	30.1	Very low	165 Å²	165	136.3 Å²	136.3	100%	1.154	81%	0.811	S	S	*	*				0	105.3	0	16.2	0	0	0	0	108.7
2	H	29.6	Very low	29.9	Very low	171 Å²	171	137.1 Å²	137.1	79%	0.792	81%	0.809	S	S	*	*			trans	38.5	116.5	159.7	-63.5	-70	0	0	0	120.5
3	L	31.2	Very low	29.6	Very low	152 Å²	152	132.2 Å²	132.2	80%	0.796	81%	0.805	S	S	*	*				60.3	126.1	78.9	-81	149.1	0	0	0	111.6
4	C	30	Very low	29.5	Very low	114 Å²	114	129.7 Å²	129.7	77%	0.77	81%	0.805	S	S	*	*			cis	-168.8	167	35.7	-93.9	0	0	0	0	107.6
5	A	29.3	Very low	29.6	Very low	92 Å²	92	129.8 Å²	129.8	76%	0.76	80%	0.804	S	S	*	*			cis	-169.3	147.9	-10.3	0	0	0	0	0	108.1
6	S	29.4	Very low	30.1	Very low	117 Å²	117	129.8 Å²	129.8	82%	0.818	81%	0.806	S	S	*	*			trans	-79	-171.2	172.5	-28.4	0	0	0	0	111.1
7	P	38.9	Very low	30.5	Very low	117 Å²	117	126.3 Å²	126.3	76%	0.76	80%	0.802	S	S	*	*			cis	-147.5	168.6	26.9	38.1	-13.8	0	0	0	119.5
8	S	30.1	Very low	30.4	Very low	98 Å²	98	129.4 Å²	129.4	69%	0.685	81%	0.805	S	S	*	*			trans	-32.1	141.6	154.1	50.2	0	0	0	0	117.5
9	L	27.1	Very low	30.7	Very low	180 Å²	180	128.6 Å²	128.6	94%	0.942	80%	0.801	S	S	*	*			trans	-127	111.5	146.1	-107.8	158.6	0	0	0	108.9
10	L	28.1	Very low	31.4	Very low	140 Å²	140	128.9 Å²	128.9	73%	0.733	80%	0.802	S	S	*	*			trans	-71	154.8	170	-94.3	144.7	0	0	0	110.8
11	Q	26	Very low	32.4	Very low	153 Å²	153	129.7 Å²	129.7	72%	0.715	79%	0.794	S	S	*	*			trans	105.8	96.5	137.1	-121.6	156.9	-2.7	0	0	119.8
12	N	27.2	Very low	34	Very low	146 Å²	146	130.7 Å²	130.7	78%	0.781	78%	0.777	S	S	*	*				56.5	134.5	117.1	-52.8	-9.1	0	0	0	118.9
13	G	26.5	Very low	36.1	Very low	74 Å²	74	124.8 Å²	124.8	76%	0.763	75%	0.752	S	S	*	*			cis	-167.1	83.2	37.8	0	0	0	0	0	113.2
14	A	27.9	Very low	38.3	Very low	97 Å²	97	120 Å²	120	80%	0.802	73%	0.725	S	S	*	*			trans	-88.8	105.4	159.2	0	0	0	0	0	108	P16	A14-P16 WeakPolarHBondContact O-CD 3.09Å
15	V	31.6	Very low	40.6	Very low	131 Å²	131	115.7 Å²	115.7	79%	0.794	70%	0.695	S	S	*	*			trans	-58.4	120.9	165.3	179.4	0	0	0	0	107.4	G17	V15-G17 PolarHBondContact O-N 2.67Å
16	P	36.8	Very low	42.6	Very low	129 Å²	129	116.6 Å²	116.6	84%	0.838	70%	0.695	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.8	110	173.6	8.1	6.9	0	0	0	107.9	A14	A14-P16 WeakPolarHBondContact O-CD 3.09Å
17	G	37.4	Very low	44.9	Very low	71 Å²	71	118 Å²	118	73%	0.732	68%	0.683	S	S	*	*	T	Hydrogen-bonded Turn	trans	147.1	9.1	167.2	0	0	0	0	0	119.9	V15	V15-G17 PolarHBondContact O-N 2.67Å
18	E	29	Very low	46.9	Very low	183 Å²	183	114.1 Å²	114.1	86%	0.855	65%	0.653	S	S	*	*			trans	-92.5	121.3	162.5	-83.5	-164.7	153.4	0	0	110	V20	E18-V20 PolarHBondContact O-N 3.29Å
19	P	36.3	Very low	49.5	Very low	113 Å²	113	109.9 Å²	109.9	73%	0.734	63%	0.625	S	S	*	*			trans	-60.7	118.9	169.6	25.7	-30.3	0	0	0	107	K21	P19-K21 PolarHBondContact O-N 3.4Å
20	V	43.3	Very low	52.4	Low	134 Å²	134	101.5 Å²	101.5	81%	0.812	58%	0.581	S	S	*	*			trans	-50.4	108.6	165.8	178.1	0	0	0	0	105.7	E18 K22	E18-V20 PolarHBondContact O-N 3.29Å; V20-K22 VanDerWaalsContact C-N 3.35Å; V20-K22 PolarHBondContact O-N 3.31Å
21	K	53.4	Low	55.3	Low	146 Å²	146	95.5 Å²	95.5	64%	0.635	55%	0.548	S	S	*	.			trans	-55.7	101.8	179.7	-84.4	175.8	179	167	0	107	P19 D23	P19-K21 PolarHBondContact O-N 3.4Å; K21-D23 PolarHBondContact O-N 2.96Å
22	K	64.5	Low	58	Low	186 Å²	186	90 Å²	90	81%	0.809	53%	0.533	S	S	*	.			trans	-59.6	138.9	173	-87.7	-179.5	173.7	176.2	0	108	V20 E24	V20-K22 VanDerWaalsContact C-N 3.35Å; V20-K22 PolarHBondContact O-N 3.31Å; K22-E24 PolarHBondContact O-N 3.07Å
23	D	75.2	Confident	60.7	Low	48 Å²	48	86.5 Å²	86.5	26%	0.257	52%	0.515	S	S	.	.			trans	-59.1	131.1	169.6	-67.8	-36.9	0	0	0	107.9	K21 N25 N30 K240	K21-D23 PolarHBondContact O-N 2.96Å; D23-N25 VanDerWaalsContact C-N 3.26Å; D23-N30 PolarHBondContact OD1-N 3.16Å; D23-K240 IonicContact OD1-NZ 4Å; D23-K240 WeakPolarHBondContact OD2-CE 3.25Å; D23-K240 IonicContact OD2-NZ 3.8Å; D23-K240 PolarHBondContact OD2-NZ 3.26Å
24	E	76.3	Confident	63.4	Low	51 Å²	51	84.4 Å²	84.4	24%	0.238	49%	0.485	C	S	.	.	S	Bend	trans	-65.6	-37.7	175.5	-168.9	-173.1	-161	0	0	109.6	K22 N30 K317 F318 L591 H594	K22-E24 PolarHBondContact O-N 3.07Å; E24-N30 PolarHBondContact N-OD1 3.4Å; E24-K317 WeakPolarHBondContact OE2-CA 2.95Å; E24-K317 WeakPolarHBondContact OE2-CB 3.47Å; E24-F318 PolarHBondContact OE2-N 3.21Å; E24-L591 HydrophobicContact CB-CD1 4.46Å; E24-L591 HydrophobicContact CG-CD1 3.6Å; E24-H594 IonicContact OE1-CD2 3.86Å; E24-H594 IonicContact OE1-CE1 2.62Å; E24-H594 PolarHBondContact OE1-CE1 3.16Å; E24-H594 VanDerWaalsContact OE1-CE1 3.28Å; E24-H594 IonicContact OE1-NE2 2.72Å; E24-H594 PolarHBondContact OE1-NE2 3.34Å
25	N	78.6	Confident	66.2	Low	24 Å²	24	84.2 Å²	84.2	13%	0.128	47%	0.469	C	S	.	.	S	Bend	trans	-115.1	94.1	172.5	-172.2	-20.8	0	0	0	110.1	D23 R27 R28 G29 N30 L591	D23-N25 VanDerWaalsContact C-N 3.26Å; N25-R27 VanDerWaalsContact C-N 3.27Å; N25-R27 PolarHBondContact O-N 3.32Å; N25-R27 PolarHBondContact OD1-N 2.93Å; N25-R28 HydrophobicContact CB-CB 4.26Å; N25-R28 WeakPolarHBondContact ND2-CB 3.3Å; N25-R28 PolarHBondContact O-N 3.36Å; N25-R28 PolarHBondContact OD1-N 2.8Å; N25-G29 VanDerWaalsContact O-CA 3.3Å; N25-G29 WeakPolarHBondContact O-CA 3.46Å; N25-G29 PolarHBondContact O-N 2.97Å; N25-N30 PolarHBondContact N-OD1 2.71Å; N25-N30 VanDerWaalsContact N-OD1 3.11Å; N25-L591 HydrophobicContact CB-CD1 4.45Å; N25-L591 HydrophobicContact CB-CD2 4.36Å
26	S	71.9	Confident	69.1	Low	110 Å²	110	78.1 Å²	78.1	77%	0.769	43%	0.432	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.2	-26.6	-179.6	59.9	0	0	0	0	114
27	R	76.8	Confident	71.6	Confident	148 Å²	148	72 Å²	72	56%	0.558	39%	0.392	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.9	-35.5	-179.7	-164.4	178.3	-169	-158.2	0.9	112.2	N25 G422 D424 I427	N25-R27 VanDerWaalsContact C-N 3.27Å; N25-R27 PolarHBondContact O-N 3.32Å; N25-R27 PolarHBondContact OD1-N 2.93Å; R27-G422 PolarHBondContact NH2-O 3.19Å; R27-D424 IonicContact CZ-OD1 3.92Å; R27-D424 IonicContact NE-OD1 2.66Å; R27-D424 IonicContact NH2-OD1 3.95Å; R27-D424 PolarHBondContact NH2-OD1 2.89Å; R27-I427 HydrophobicContact CG-CD1 4.38Å; R27-I427 HydrophobicContact CG-CG2 4.18Å; R27-I427 VanDerWaalsContact NH2-CD1 3.33Å
28	R	80.9	Confident	74.2	Confident	34 Å²	34	69.8 Å²	69.8	13%	0.128	37%	0.365	C	S	.	.	T	Hydrogen-bonded Turn	trans	-91.5	-35.5	178	-167.4	178.4	-167	86.6	15.3	112.2	N25 S93 S314 Y315 T415 D419	N25-R28 HydrophobicContact CB-CB 4.26Å; N25-R28 WeakPolarHBondContact ND2-CB 3.3Å; N25-R28 PolarHBondContact O-N 3.36Å; N25-R28 PolarHBondContact OD1-N 2.8Å; R28-S93 VanDerWaalsContact CZ-O 3.26Å; R28-S93 PolarHBondContact NE-O 2.9Å; R28-S93 PolarHBondContact NH1-O 3.22Å; R28-S314 WeakPolarHBondContact CD-O 3.49Å; R28-S314 PolarHBondContact NE-O 3.11Å; R28-S314 VanDerWaalsContact NE-O 3.14Å; R28-S314 PolarHBondContact NE-OG 3.36Å; R28-S314 VanDerWaalsContact NE-OG 3.07Å; R28-S314 VanDerWaalsContact NH2-CB 3.31Å; R28-S314 PolarHBondContact NH2-OG 2.93Å; R28-Y315 HydrophobicContact CG-CD1 3.82Å; R28-Y315 HydrophobicContact CG-CE1 3.58Å; R28-Y315 WeakPolarHBondContact O-CE1 3.47Å; R28-T415 VanDerWaalsContact NH2-CG2 3.33Å; R28-D419 IonicContact CZ-OD2 3.28Å; R28-D419 IonicContact NH1-OD1 3Å; R28-D419 IonicContact NH1-OD2 3.78Å; R28-D419 PolarHBondContact NH1-OD2 2.68Å; R28-D419 IonicContact NH2-OD2 2.64Å; R28-D419 PolarHBondContact NH2-OD2 2.83Å; R28-D419 VanDerWaalsContact NH2-OD2 3.08Å
29	G	84.2	Confident	77.1	Confident	9 Å²	9	62.6 Å²	62.6	9%	0.093	33%	0.332	C	S	.	.			trans	80.6	159.6	-164.2	0	0	0	0	0	111.8	N25 Y315	N25-G29 VanDerWaalsContact O-CA 3.3Å; N25-G29 WeakPolarHBondContact O-CA 3.46Å; N25-G29 PolarHBondContact O-N 2.97Å; G29-Y315 WeakPolarHBondContact O-CD1 3.48Å
30	N	89	Confident	79.8	Confident	4 Å²	4	57.6 Å²	57.6	2%	0.021	30%	0.299	C	S	.	.			trans	-123	165.8	171.2	-67	113.7	0	0	0	110.8	D23 E24 N25 Y315	D23-N30 PolarHBondContact OD1-N 3.16Å; E24-N30 PolarHBondContact N-OD1 3.4Å; N25-N30 PolarHBondContact N-OD1 2.71Å; N25-N30 VanDerWaalsContact N-OD1 3.11Å; N30-Y315 VanDerWaalsContact CA-O 3.32Å; N30-Y315 WeakPolarHBondContact CA-O 3.34Å; N30-Y315 PolarHBondContact ND2-O 3.01Å
31	W	88.1	Confident	82.2	Confident	14 Å²	14	51.2 Å²	51.2	5%	0.053	26%	0.261	C	S	.	.			trans	-57.6	138.9	164.7	-64.3	105.8	0	0	0	110.4	N33 E36 F37 T40 V239 M312 Y315 N316	W31-N33 VanDerWaalsContact C-N 3.31Å; W31-N33 PolarHBondContact O-N 3.4Å; W31-E36 HydrophobicContact CE3-CB 4.04Å; W31-F37 HydrophobicContact CD2-CB 4.11Å; W31-F37 HydrophobicContact CG-CB 3.93Å; W31-F37 AromaticContact NE1-CD2 3.6Å; W31-T40 HydrophobicContact CH2-CG2 3.83Å; W31-T40 HydrophobicContact CZ2-CG2 4.48Å; W31-V239 HydrophobicContact CD2-CB 4.49Å; W31-V239 HydrophobicContact CE3-CB 4.06Å; W31-V239 HydrophobicContact CH2-CB 3.75Å; W31-V239 HydrophobicContact CH2-CG1 3.65Å; W31-V239 HydrophobicContact CZ2-CB 4.23Å; W31-V239 HydrophobicContact CZ2-CG1 3.9Å; W31-V239 HydrophobicContact CZ3-CB 3.67Å; W31-V239 HydrophobicContact CZ3-CG1 4.14Å; W31-V239 WeakPolarHBondContact CZ3-O 3.42Å; W31-M312 HydrophobicContact CH2-SD 3.78Å; W31-M312 HydrophobicContact CZ2-CB 4.37Å; W31-M312 HydrophobicContact CZ2-SD 3.56Å; W31-M312 VanDerWaalsContact CZ2-SD 3.56Å; W31-M312 PolarHBondContact NE1-O 2.93Å; W31-Y315 PolarHBondContact N-O 3.4Å; W31-N316 PolarHBondContact NE1-OD1 3.22Å
32	G	82.8	Confident	84.1	Confident	39 Å²	39	44.7 Å²	44.7	40%	0.402	23%	0.233	S	C	.	.	S	Bend	trans	-64.2	-42.2	177.1	0	0	0	0	0	110.8	E36	G32-E36 VanDerWaalsContact CA-OE2 3.29Å; G32-E36 WeakPolarHBondContact CA-OE2 3.3Å; G32-E36 PolarHBondContact N-OE2 3.24Å
33	N	84.4	Confident	85.4	Confident	72 Å²	72	36.1 Å²	36.1	39%	0.385	20%	0.198	S	C	.	.	S	Bend	trans	-142.5	157.1	176.5	-75.4	-40	0	0	0	112.5	W31 I35 E36	W31-N33 VanDerWaalsContact C-N 3.31Å; W31-N33 PolarHBondContact O-N 3.4Å; N33-I35 VanDerWaalsContact C-N 3.27Å; N33-I35 PolarHBondContact O-N 3.43Å; N33-E36 HydrophobicContact CB-CG 4.17Å; N33-E36 PolarHBondContact N-OE2 3.3Å; N33-E36 VanDerWaalsContact O-CB 3.31Å; N33-E36 WeakPolarHBondContact O-CB 3.35Å; N33-E36 PolarHBondContact O-N 2.92Å; N33-E36 VanDerWaalsContact O-N 3.09Å
34	Q	83.6	Confident	86.3	Confident	29 Å²	29	34.1 Å²	34.1	14%	0.136	19%	0.186	C	C	.	.	H	α-helix	trans	-62.3	-33.4	179.2	-172.6	61.1	16	0	0	113.5	E36 F37 V38 N320 D328	Q34-E36 PolarHBondContact O-N 2.88Å; Q34-F37 WeakPolarHBondContact O-CB 3.35Å; Q34-F37 PolarHBondContact O-N 2.92Å; Q34-V38 WeakPolarHBondContact O-CG2 3.37Å; Q34-V38 PolarHBondContact O-N 3.14Å; Q34-N320 PolarHBondContact NE2-ND2 2.9Å; Q34-N320 PolarHBondContact OE1-ND2 3.48Å; Q34-N320 PolarHBondContact OE1-OD1 3.33Å; Q34-D328 PolarHBondContact NE2-OD2 3.25Å
35	I	87.2	Confident	87.1	Confident	94 Å²	94	31.8 Å²	31.8	48%	0.482	18%	0.176	S	C	.	.	H	α-helix	trans	-63.1	-33.9	177.8	-67.2	167.2	0	0	0	110.5	N33 F37 V38 L39 Y247	N33-I35 VanDerWaalsContact C-N 3.27Å; N33-I35 PolarHBondContact O-N 3.43Å; I35-F37 VanDerWaalsContact C-N 3.35Å; I35-F37 PolarHBondContact O-N 3.34Å; I35-V38 PolarHBondContact O-N 3.34Å; I35-L39 HydrophobicContact CG2-CD1 3.64Å; I35-L39 HydrophobicContact CG2-CG 3.94Å; I35-L39 WeakPolarHBondContact O-CB 3.31Å; I35-L39 WeakPolarHBondContact O-CG 3.43Å; I35-L39 PolarHBondContact O-N 3.03Å; I35-Y247 HydrophobicContact CG2-CE1 3.7Å
36	E	90.6	Very high	87.8	Confident	2 Å²	2	30.9 Å²	30.9	1%	0.009	17%	0.172	C	C	.	.	H	α-helix	trans	-63.7	-42.4	177.3	-57.2	177.3	170.8	0	0	110.7	W31 G32 N33 Q34 T40 G243 K244 Y247	W31-E36 HydrophobicContact CE3-CB 4.04Å; G32-E36 VanDerWaalsContact CA-OE2 3.29Å; G32-E36 WeakPolarHBondContact CA-OE2 3.3Å; G32-E36 PolarHBondContact N-OE2 3.24Å; N33-E36 HydrophobicContact CB-CG 4.17Å; N33-E36 PolarHBondContact N-OE2 3.3Å; N33-E36 VanDerWaalsContact O-CB 3.31Å; N33-E36 WeakPolarHBondContact O-CB 3.35Å; N33-E36 PolarHBondContact O-N 2.92Å; N33-E36 VanDerWaalsContact O-N 3.09Å; Q34-E36 PolarHBondContact O-N 2.88Å; E36-T40 WeakPolarHBondContact O-CB 3.25Å; E36-T40 PolarHBondContact O-N 3.37Å; E36-T40 PolarHBondContact O-OG1 2.79Å; E36-G243 WeakPolarHBondContact CG-O 3.07Å; E36-K244 VanDerWaalsContact OE1-CE 3.27Å; E36-K244 WeakPolarHBondContact OE1-CE 3.24Å; E36-K244 IonicContact OE1-NZ 2.85Å; E36-K244 PolarHBondContact OE1-NZ 2.83Å; E36-Y247 HydrophobicContact CG-CE2 3.75Å
37	F	90.3	Very high	88.6	Confident	0 Å²	0	25.9 Å²	25.9	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-62.3	-48	173.5	165.3	-103.7	0	0	0	112.1	W31 Q34 I35 T40 S41 L86 M312 N316 D328 I332	W31-F37 HydrophobicContact CD2-CB 4.11Å; W31-F37 HydrophobicContact CG-CB 3.93Å; W31-F37 AromaticContact NE1-CD2 3.6Å; Q34-F37 WeakPolarHBondContact O-CB 3.35Å; Q34-F37 PolarHBondContact O-N 2.92Å; I35-F37 VanDerWaalsContact C-N 3.35Å; I35-F37 PolarHBondContact O-N 3.34Å; F37-T40 PolarHBondContact O-N 3.15Å; F37-S41 WeakPolarHBondContact CE2-OG 3.36Å; F37-S41 WeakPolarHBondContact O-CB 3.46Å; F37-S41 PolarHBondContact O-N 2.9Å; F37-S41 PolarHBondContact O-OG 3.42Å; F37-L86 HydrophobicContact CE2-CD2 4.24Å; F37-L86 HydrophobicContact CZ-CD1 4.23Å; F37-L86 HydrophobicContact CZ-CD2 3.88Å; F37-M312 HydrophobicContact CE2-CB 4.34Å; F37-N316 VanDerWaalsContact CD2-OD1 3.29Å; F37-N316 WeakPolarHBondContact CD2-OD1 3.24Å; F37-N316 VanDerWaalsContact CE2-ND2 3.35Å; F37-N316 WeakPolarHBondContact CE2-ND2 3.37Å; F37-N316 WeakPolarHBondContact CG-OD1 3.41Å; F37-N316 WeakPolarHBondContact CZ-ND2 3.4Å; F37-D328 HydrophobicContact CE1-CB 4.48Å; F37-I332 HydrophobicContact CE1-CD1 4.48Å
38	V	90.9	Very high	89.2	Confident	25 Å²	25	18.9 Å²	18.9	15%	0.152	11%	0.111	C	C	.	.	H	α-helix	trans	-64.1	-48.1	-178.6	174.5	0	0	0	0	110.6	Q34 I35 T40 S41 V42 D328 I332	Q34-V38 WeakPolarHBondContact O-CG2 3.37Å; Q34-V38 PolarHBondContact O-N 3.14Å; I35-V38 PolarHBondContact O-N 3.34Å; V38-T40 VanDerWaalsContact C-N 3.35Å; V38-T40 PolarHBondContact O-N 3Å; V38-S41 PolarHBondContact O-N 3.09Å; V38-V42 HydrophobicContact CG1-CG2 4.43Å; V38-V42 WeakPolarHBondContact O-CG2 3.44Å; V38-V42 PolarHBondContact O-N 2.99Å; V38-D328 HydrophobicContact CG2-CB 4.24Å; V38-I332 HydrophobicContact CG1-CG1 4.14Å
39	L	91.9	Very high	89.5	Confident	33 Å²	33	18.2 Å²	18.2	17%	0.173	11%	0.114	C	C	.	.	H	α-helix	trans	-65.5	-37	178.3	-70.2	179.3	0	0	0	112.1	I35 S41 V42 G43 V246 Y247	I35-L39 HydrophobicContact CG2-CD1 3.64Å; I35-L39 HydrophobicContact CG2-CG 3.94Å; I35-L39 WeakPolarHBondContact O-CB 3.31Å; I35-L39 WeakPolarHBondContact O-CG 3.43Å; I35-L39 PolarHBondContact O-N 3.03Å; L39-S41 VanDerWaalsContact C-N 3.35Å; L39-V42 PolarHBondContact O-N 2.89Å; L39-G43 PolarHBondContact O-N 3.34Å; L39-V246 HydrophobicContact CB-CG1 3.88Å; L39-V246 HydrophobicContact CB-CG2 4.16Å; L39-V246 WeakPolarHBondContact O-CG2 3.23Å; L39-Y247 HydrophobicContact CD1-CD1 3.6Å; L39-Y247 HydrophobicContact CD1-CE1 3.79Å; L39-Y247 HydrophobicContact CD1-CG 4.22Å
40	T	92.7	Very high	89.8	Confident	7 Å²	7	17.9 Å²	17.9	4%	0.043	11%	0.111	C	C	.	.	H	α-helix	trans	-62.9	-42.7	172.6	-57.3	0	0	0	0	111.5	W31 E36 F37 V38 G43 Y44 M312	W31-T40 HydrophobicContact CH2-CG2 3.83Å; W31-T40 HydrophobicContact CZ2-CG2 4.48Å; E36-T40 WeakPolarHBondContact O-CB 3.25Å; E36-T40 PolarHBondContact O-N 3.37Å; E36-T40 PolarHBondContact O-OG1 2.79Å; F37-T40 PolarHBondContact O-N 3.15Å; V38-T40 VanDerWaalsContact C-N 3.35Å; V38-T40 PolarHBondContact O-N 3Å; T40-G43 PolarHBondContact O-N 2.76Å; T40-Y44 WeakPolarHBondContact O-CB 3.44Å; T40-Y44 PolarHBondContact O-N 3.49Å; T40-M312 HydrophobicContact CG2-CE 4.39Å; T40-M312 HydrophobicContact CG2-CG 4.47Å; T40-M312 HydrophobicContact CG2-SD 3.87Å
41	S	92.3	Very high	89.8	Confident	1 Å²	1	17.8 Å²	17.8	1%	0.007	11%	0.11	C	C	.	.	H	α-helix	trans	-69.5	-36.1	178.5	-56	0	0	0	0	112.1	F37 V38 L39 Y44 A45 I332	F37-S41 WeakPolarHBondContact CE2-OG 3.36Å; F37-S41 WeakPolarHBondContact O-CB 3.46Å; F37-S41 PolarHBondContact O-N 2.9Å; F37-S41 PolarHBondContact O-OG 3.42Å; V38-S41 PolarHBondContact O-N 3.09Å; L39-S41 VanDerWaalsContact C-N 3.35Å; S41-Y44 PolarHBondContact O-N 2.98Å; S41-A45 WeakPolarHBondContact O-CB 3.48Å; S41-A45 PolarHBondContact O-N 3.07Å; S41-I332 VanDerWaalsContact CB-CD1 3.45Å
42	V	93.3	Very high	89.5	Confident	9 Å²	9	18.5 Å²	18.5	6%	0.055	11%	0.113	C	C	.	.	H	α-helix	trans	-65.2	-46.4	171	170.5	0	0	0	0	110.6	V38 L39 Y44 A45 V46 I332 T335	V38-V42 HydrophobicContact CG1-CG2 4.43Å; V38-V42 WeakPolarHBondContact O-CG2 3.44Å; V38-V42 PolarHBondContact O-N 2.99Å; L39-V42 PolarHBondContact O-N 2.89Å; V42-Y44 PolarHBondContact O-N 3.28Å; V42-A45 PolarHBondContact O-N 3.48Å; V42-V46 HydrophobicContact CG1-CG2 3.97Å; V42-V46 VanDerWaalsContact O-CB 3.28Å; V42-V46 WeakPolarHBondContact O-CB 3.25Å; V42-V46 WeakPolarHBondContact O-CG2 3.47Å; V42-V46 PolarHBondContact O-N 3.23Å; V42-I332 HydrophobicContact CG2-CB 4.39Å; V42-I332 HydrophobicContact CG2-CG1 4.1Å; V42-I332 HydrophobicContact CG2-CG2 4.15Å; V42-T335 HydrophobicContact CG1-CG2 3.9Å; V42-T335 HydrophobicContact CG2-CG2 4.23Å
43	G	92.6	Very high	89.8	Confident	6 Å²	6	19.6 Å²	19.6	6%	0.062	11%	0.105	C	C	.	.	H	α-helix	trans	-65.9	-25.6	177.2	0	0	0	0	0	113.4	L39 T40 G404 T405	L39-G43 PolarHBondContact O-N 3.34Å; T40-G43 PolarHBondContact O-N 2.76Å; G43-G404 CarbonylContact O-C 3.54Å; G43-G404 WeakPolarHBondContact O-CA 3.41Å; G43-T405 PolarHBondContact O-N 2.85Å; G43-T405 VanDerWaalsContact O-N 3.13Å
44	Y	93.9	Very high	90.1	Very high	5 Å²	5	16.1 Å²	16.1	2%	0.02	9%	0.086	C	C	.	.	H	α-helix	trans	-71.8	-48.1	171.4	171.4	-116.1	0	0	0	112.1	T40 S41 V42 G303 W306 L309 T405 C408	T40-Y44 WeakPolarHBondContact O-CB 3.44Å; T40-Y44 PolarHBondContact O-N 3.49Å; S41-Y44 PolarHBondContact O-N 2.98Å; V42-Y44 PolarHBondContact O-N 3.28Å; Y44-G303 WeakPolarHBondContact OH-CA 3.31Å; Y44-G303 PolarHBondContact OH-O 2.84Å; Y44-W306 HydrophobicContact CE2-CE3 4.05Å; Y44-W306 HydrophobicContact CE2-CZ3 4.47Å; Y44-W306 VanDerWaalsContact OH-CB 3.31Å; Y44-W306 WeakPolarHBondContact OH-CB 3.49Å; Y44-W306 VanDerWaalsContact OH-CE3 3.27Å; Y44-L309 HydrophobicContact CD1-CD2 3.59Å; Y44-L309 HydrophobicContact CD1-CG 4.31Å; Y44-L309 HydrophobicContact CE1-CD2 3.58Å; Y44-L309 HydrophobicContact CE1-CG 3.78Å; Y44-T405 HydrophobicContact CD2-CG2 4.15Å; Y44-T405 HydrophobicContact CE2-CG2 4.35Å; Y44-T405 PolarHBondContact O-OG1 2.96Å; Y44-C408 HydrophobicContact CD2-CB 3.25Å; Y44-C408 WeakPolarHBondContact CD2-SG 3.36Å; Y44-C408 HydrophobicContact CE2-CB 3.87Å; Y44-C408 VanDerWaalsContact CE2-SG 3.56Å; Y44-C408 HydrophobicContact CG-CB 3.81Å
45	A	92.5	Very high	90.4	Very high	3 Å²	3	14.8 Å²	14.8	3%	0.025	8%	0.08	C	C	.	.	H	α-helix	trans	-74.7	-39.5	-178	0	0	0	0	0	112.9	S41 V42 G47 N50 S301 N336	S41-A45 WeakPolarHBondContact O-CB 3.48Å; S41-A45 PolarHBondContact O-N 3.07Å; V42-A45 PolarHBondContact O-N 3.48Å; A45-G47 PolarHBondContact O-N 2.86Å; A45-N50 PolarHBondContact O-OD1 3.47Å; A45-S301 CarbonylContact C-O 3.55Å; A45-S301 WeakPolarHBondContact CA-O 3.46Å; A45-N336 HydrophobicContact CB-CB 4Å; A45-N336 PolarHBondContact O-OD1 2.91Å
46	V	93.3	Very high	90.3	Very high	5 Å²	5	12.1 Å²	12.1	3%	0.03	6%	0.064	C	C	.	.	S	Bend	trans	-85.2	96.2	177.3	-176.7	0	0	0	0	108.9	V42 N50 N336 T339 L401	V42-V46 HydrophobicContact CG1-CG2 3.97Å; V42-V46 VanDerWaalsContact O-CB 3.28Å; V42-V46 WeakPolarHBondContact O-CB 3.25Å; V42-V46 WeakPolarHBondContact O-CG2 3.47Å; V42-V46 PolarHBondContact O-N 3.23Å; V46-N50 WeakPolarHBondContact CA-OD1 3.27Å; V46-N336 HydrophobicContact CG2-CB 4.28Å; V46-T339 HydrophobicContact CG1-CG2 3.59Å; V46-T339 HydrophobicContact CG2-CG2 4.44Å; V46-L401 HydrophobicContact CG1-CD2 3.84Å
47	G	89.9	Confident	90.2	Very high	4 Å²	4	12.6 Å²	12.6	4%	0.041	7%	0.067	C	C	.	.	S	Bend	trans	-120	-165.5	178	0	0	0	0	0	112.9	A45 G49 N50 Y124	A45-G47 PolarHBondContact O-N 2.86Å; G47-G49 PolarHBondContact O-N 3.43Å; G47-N50 PolarHBondContact N-OD1 3.22Å; G47-N50 WeakPolarHBondContact O-CB 3.36Å; G47-N50 PolarHBondContact O-N 2.88Å; G47-N50 VanDerWaalsContact O-N 3.14Å; G47-N50 PolarHBondContact O-OD1 3.12Å; G47-Y124 WeakPolarHBondContact CA-OH 3.44Å
48	L	88.3	Confident	90.2	Very high	2 Å²	2	12.6 Å²	12.6	1%	0.01	7%	0.067	C	C	.	.	H	α-helix	trans	-60.4	-30.8	178.6	-64.8	169.3	0	0	0	112.6	N50 V51 W52 Y124 V127 L398 L401	L48-N50 PolarHBondContact O-N 2.62Å; L48-V51 PolarHBondContact O-N 3.01Å; L48-W52 HydrophobicContact CB-CD2 3.94Å; L48-W52 HydrophobicContact CB-CE3 4Å; L48-W52 HydrophobicContact CB-CH2 3.96Å; L48-W52 HydrophobicContact CB-CZ2 3.66Å; L48-W52 HydrophobicContact CB-CZ3 4.04Å; L48-W52 HydrophobicContact CD1-CH2 3.81Å; L48-W52 HydrophobicContact CD1-CZ2 4.09Å; L48-W52 HydrophobicContact CD1-CZ3 4.16Å; L48-W52 HydrophobicContact CD2-CE3 4.29Å; L48-W52 HydrophobicContact CD2-CH2 4.49Å; L48-W52 HydrophobicContact CD2-CZ3 4.03Å; L48-W52 HydrophobicContact CG-CH2 4.33Å; L48-W52 HydrophobicContact CG-CZ2 4.46Å; L48-W52 HydrophobicContact CG-CZ3 4.33Å; L48-W52 VanDerWaalsContact O-CG 3.31Å; L48-W52 PolarHBondContact O-N 3.14Å; L48-Y124 HydrophobicContact CB-CE2 4.39Å; L48-Y124 HydrophobicContact CD1-CE1 4.41Å; L48-Y124 HydrophobicContact CD1-CE2 4.08Å; L48-Y124 HydrophobicContact CG-CE2 4.47Å; L48-Y124 PolarHBondContact N-OH 3.41Å; L48-Y124 VanDerWaalsContact N-OH 3.11Å; L48-V127 HydrophobicContact CD1-CB 4.31Å; L48-V127 HydrophobicContact CD1-CG1 3.33Å; L48-L398 HydrophobicContact CD2-CB 3.92Å; L48-L398 HydrophobicContact CD2-CD2 3.68Å; L48-L398 HydrophobicContact CD2-CG 4.32Å; L48-L398 WeakPolarHBondContact CD2-O 3.3Å; L48-L401 HydrophobicContact CD2-CB 4.48Å
49	G	87.4	Confident	89.9	Confident	20 Å²	20	13.2 Å²	13.2	21%	0.206	7%	0.067	C	C	.	.	H	α-helix	trans	-60.4	-27.9	177.2	0	0	0	0	0	114	G47 V51 R53 F54	G47-G49 PolarHBondContact O-N 3.43Å; G49-V51 VanDerWaalsContact C-N 3.31Å; G49-R53 WeakPolarHBondContact O-CA 3.49Å; G49-R53 VanDerWaalsContact O-CB 3.28Å; G49-R53 WeakPolarHBondContact O-CB 3.45Å; G49-R53 PolarHBondContact O-N 2.82Å; G49-R53 VanDerWaalsContact O-N 3.08Å; G49-F54 PolarHBondContact O-N 3.33Å
50	N	91.8	Very high	89.6	Confident	2 Å²	2	16 Å²	16	1%	0.011	8%	0.075	C	C	.	.	H	α-helix	trans	-69.7	-31.3	176.3	-59.1	72.3	0	0	0	111.8	A45 V46 G47 L48 S301 N336 S340	A45-N50 PolarHBondContact O-OD1 3.47Å; V46-N50 WeakPolarHBondContact CA-OD1 3.27Å; G47-N50 PolarHBondContact N-OD1 3.22Å; G47-N50 WeakPolarHBondContact O-CB 3.36Å; G47-N50 PolarHBondContact O-N 2.88Å; G47-N50 VanDerWaalsContact O-N 3.14Å; G47-N50 PolarHBondContact O-OD1 3.12Å; L48-N50 PolarHBondContact O-N 2.62Å; N50-S301 PolarHBondContact ND2-OG 3.09Å; N50-N336 PolarHBondContact ND2-O 3.27Å; N50-N336 PolarHBondContact ND2-OD1 3.12Å; N50-S340 PolarHBondContact ND2-OG 2.85Å
51	V	87.9	Confident	89.4	Confident	2 Å²	2	16 Å²	16	1%	0.012	8%	0.075	C	C	.	.	H	α-helix	trans	-90.1	-41	-175.1	-178.7	0	0	0	0	111.9	L48 G49 P55 A343 I347 M397 L398 L401	L48-V51 PolarHBondContact O-N 3.01Å; G49-V51 VanDerWaalsContact C-N 3.31Å; V51-P55 WeakPolarHBondContact O-CD 3.36Å; V51-P55 WeakPolarHBondContact O-CG 3.2Å; V51-A343 HydrophobicContact CG2-CB 4.26Å; V51-I347 HydrophobicContact CG1-CD1 3.77Å; V51-I347 HydrophobicContact CG1-CG1 4.41Å; V51-I347 WeakPolarHBondContact O-CG1 3.24Å; V51-M397 HydrophobicContact CG1-CE 4.44Å; V51-L398 HydrophobicContact CG1-CD2 4.33Å; V51-L401 HydrophobicContact CG2-CD1 3.54Å
52	W	82.5	Confident	89.2	Confident	28 Å²	28	16 Å²	16	11%	0.106	7%	0.074	C	C	.	.	H	α-helix	trans	-110.1	-26.1	-174.8	61.6	55.2	0	0	0	115.1	L48 Y56 V127 L372 A373 F374	L48-W52 HydrophobicContact CB-CD2 3.94Å; L48-W52 HydrophobicContact CB-CE3 4Å; L48-W52 HydrophobicContact CB-CH2 3.96Å; L48-W52 HydrophobicContact CB-CZ2 3.66Å; L48-W52 HydrophobicContact CB-CZ3 4.04Å; L48-W52 HydrophobicContact CD1-CH2 3.81Å; L48-W52 HydrophobicContact CD1-CZ2 4.09Å; L48-W52 HydrophobicContact CD1-CZ3 4.16Å; L48-W52 HydrophobicContact CD2-CE3 4.29Å; L48-W52 HydrophobicContact CD2-CH2 4.49Å; L48-W52 HydrophobicContact CD2-CZ3 4.03Å; L48-W52 HydrophobicContact CG-CH2 4.33Å; L48-W52 HydrophobicContact CG-CZ2 4.46Å; L48-W52 HydrophobicContact CG-CZ3 4.33Å; L48-W52 VanDerWaalsContact O-CG 3.31Å; L48-W52 PolarHBondContact O-N 3.14Å; W52-Y56 WeakPolarHBondContact O-CB 3.02Å; W52-V127 HydrophobicContact CH2-CG1 3.24Å; W52-V127 HydrophobicContact CZ2-CG1 4Å; W52-V127 HydrophobicContact CZ3-CG1 4.08Å; W52-L372 HydrophobicContact CB-CD2 4.23Å; W52-L372 VanDerWaalsContact O-CD2 3.31Å; W52-L372 WeakPolarHBondContact O-CD2 3.06Å; W52-A373 HydrophobicContact CB-CB 4.48Å; W52-A373 HydrophobicContact CD2-CB 4.16Å; W52-A373 HydrophobicContact CE3-CB 3.24Å; W52-A373 HydrophobicContact CH2-CB 4.44Å; W52-A373 HydrophobicContact CZ3-CB 3.4Å; W52-F374 HydrophobicContact CH2-CE2 4.1Å; W52-F374 AromaticContact CZ3-CE2 3.95Å; W52-F374 HydrophobicContact CZ3-CE2 3.95Å; W52-F374 HydrophobicContact CZ3-CZ 4.21Å
53	R	88.1	Confident	89	Confident	62 Å²	62	15.7 Å²	15.7	23%	0.234	7%	0.073	C	C	.	.	H	α-helix	trans	-94.2	-46.8	-172.2	-172.2	178.3	175.3	170.3	-1.5	110.4	G49 Y56 L57 Q297	G49-R53 WeakPolarHBondContact O-CA 3.49Å; G49-R53 VanDerWaalsContact O-CB 3.28Å; G49-R53 WeakPolarHBondContact O-CB 3.45Å; G49-R53 PolarHBondContact O-N 2.82Å; G49-R53 VanDerWaalsContact O-N 3.08Å; R53-Y56 WeakPolarHBondContact O-CB 3.48Å; R53-Y56 PolarHBondContact O-N 3.09Å; R53-L57 HydrophobicContact CG-CD1 4.04Å; R53-L57 HydrophobicContact CG-CG 4.34Å; R53-L57 WeakPolarHBondContact O-CG 3.46Å; R53-L57 PolarHBondContact O-N 3.27Å; R53-Q297 VanDerWaalsContact CD-OE1 3.23Å
54	F	92	Very high	88.9	Confident	0 Å²	0	16.2 Å²	16.2	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-61.5	-48.5	-179.8	176.6	-92.2	0	0	0	113.1	G49 Y56 L57 C58 F66 M67 Y70 Q297 S340 V341	G49-F54 PolarHBondContact O-N 3.33Å; F54-Y56 VanDerWaalsContact C-N 3.25Å; F54-Y56 PolarHBondContact O-N 3.25Å; F54-L57 PolarHBondContact O-N 3.32Å; F54-C58 WeakPolarHBondContact O-CB 3.19Å; F54-C58 PolarHBondContact O-N 3.11Å; F54-F66 HydrophobicContact CE2-CE1 4.21Å; F54-M67 HydrophobicContact CE1-CE 3.88Å; F54-M67 HydrophobicContact CE1-SD 4.38Å; F54-M67 HydrophobicContact CZ-CE 3.73Å; F54-M67 HydrophobicContact CZ-SD 3.63Å; F54-Y70 HydrophobicContact CD2-CD2 4.39Å; F54-Y70 HydrophobicContact CD2-CE1 4.36Å; F54-Y70 AromaticContact CD2-CE2 3.88Å; F54-Y70 HydrophobicContact CD2-CE2 3.88Å; F54-Y70 AromaticContact CD2-CZ 3.85Å; F54-Y70 AromaticContact CE2-CD1 3.76Å; F54-Y70 HydrophobicContact CE2-CD1 3.76Å; F54-Y70 AromaticContact CE2-CD2 3.88Å; F54-Y70 HydrophobicContact CE2-CD2 3.88Å; F54-Y70 AromaticContact CE2-CE1 3.5Å; F54-Y70 HydrophobicContact CE2-CE1 3.5Å; F54-Y70 AromaticContact CE2-CE2 3.64Å; F54-Y70 HydrophobicContact CE2-CE2 3.64Å; F54-Y70 AromaticContact CE2-CG 3.92Å; F54-Y70 HydrophobicContact CE2-CG 3.92Å; F54-Y70 AromaticContact CE2-CZ 3.43Å; F54-Y70 VanDerWaalsContact CE2-CZ 3.43Å; F54-Y70 HydrophobicContact CZ-CD1 4.27Å; F54-Y70 HydrophobicContact CZ-CE1 4.06Å; F54-Q297 HydrophobicContact CD2-CG 4.12Å; F54-S340 VanDerWaalsContact CD1-O 3.24Å; F54-S340 WeakPolarHBondContact CD1-O 3.39Å; F54-S340 VanDerWaalsContact CG-CB 3.5Å; F54-V341 HydrophobicContact CE1-CG2 4.06Å; F54-V341 HydrophobicContact CZ-CG2 3.9Å
55	P	89.6	Confident	88.9	Confident	1 Å²	1	16 Å²	16	1%	0.006	8%	0.078	C	C	.	.	H	α-helix	trans	-61.3	-38.6	178.6	-25.8	39.2	0	0	0	111.7	V51 C58 Y59 I347 F348	V51-P55 WeakPolarHBondContact O-CD 3.36Å; V51-P55 WeakPolarHBondContact O-CG 3.2Å; P55-C58 PolarHBondContact O-N 3.23Å; P55-Y59 WeakPolarHBondContact O-CD1 3.48Å; P55-Y59 PolarHBondContact O-N 3.19Å; P55-I347 HydrophobicContact CB-CB 4.38Å; P55-I347 HydrophobicContact CB-CG2 3.84Å; P55-I347 HydrophobicContact CG-CB 4.4Å; P55-I347 HydrophobicContact CG-CG1 4.09Å; P55-I347 HydrophobicContact CG-CG2 4.34Å; P55-F348 HydrophobicContact CB-CD2 4.2Å; P55-F348 HydrophobicContact CB-CE2 3.66Å; P55-F348 WeakPolarHBondContact O-CE2 3.42Å
56	Y	85.1	Confident	88.9	Confident	38 Å²	38	15.8 Å²	15.8	15%	0.149	8%	0.076	C	C	.	.	H	α-helix	trans	-58.9	-52.1	173.9	171.4	-95.5	0	0	0	112.7	W52 R53 F54 C58 Y59 R60 H368	W52-Y56 WeakPolarHBondContact O-CB 3.02Å; R53-Y56 WeakPolarHBondContact O-CB 3.48Å; R53-Y56 PolarHBondContact O-N 3.09Å; F54-Y56 VanDerWaalsContact C-N 3.25Å; F54-Y56 PolarHBondContact O-N 3.25Å; Y56-C58 VanDerWaalsContact C-N 3.29Å; Y56-C58 PolarHBondContact O-N 3.09Å; Y56-Y59 VanDerWaalsContact CA-CD1 3.45Å; Y56-Y59 HydrophobicContact CD2-CD1 4.37Å; Y56-Y59 AromaticContact CD2-CE1 3.33Å; Y56-Y59 HydrophobicContact CD2-CE1 3.33Å; Y56-Y59 AromaticContact CD2-CZ 3.52Å; Y56-Y59 VanDerWaalsContact CD2-OH 3.24Å; Y56-Y59 WeakPolarHBondContact CD2-OH 3.26Å; Y56-Y59 AromaticContact CE2-CE1 3.99Å; Y56-Y59 HydrophobicContact CE2-CE1 3.99Å; Y56-Y59 AromaticContact CE2-CZ 3.66Å; Y56-Y59 WeakPolarHBondContact CE2-OH 3.16Å; Y56-Y59 HydrophobicContact CG-CE1 4.01Å; Y56-Y59 WeakPolarHBondContact O-CD1 3.32Å; Y56-Y59 WeakPolarHBondContact O-CE1 3.49Å; Y56-Y59 PolarHBondContact O-N 2.99Å; Y56-R60 WeakPolarHBondContact O-CB 3.43Å; Y56-R60 PolarHBondContact O-N 3.18Å; Y56-R60 VanDerWaalsContact OH-CD 3.26Å; Y56-R60 WeakPolarHBondContact OH-CD 3.31Å; Y56-R60 PolarHBondContact OH-NH1 3.08Å; Y56-H368 HydrophobicContact CD2-CB 3.64Å; Y56-H368 HydrophobicContact CE1-CB 4.19Å; Y56-H368 HydrophobicContact CE2-CB 3.23Å; Y56-H368 HydrophobicContact CG-CB 4.32Å
57	L	87.9	Confident	88.9	Confident	11 Å²	11	16.6 Å²	16.6	6%	0.058	8%	0.08	C	C	.	.	H	α-helix	trans	-63.2	-37.6	179.3	-71.6	177.4	0	0	0	112	R53 F54 N61 F66 D293 Q297	R53-L57 HydrophobicContact CG-CD1 4.04Å; R53-L57 HydrophobicContact CG-CG 4.34Å; R53-L57 WeakPolarHBondContact O-CG 3.46Å; R53-L57 PolarHBondContact O-N 3.27Å; F54-L57 PolarHBondContact O-N 3.32Å; L57-N61 VanDerWaalsContact O-CB 3.24Å; L57-N61 WeakPolarHBondContact O-CB 3.48Å; L57-N61 PolarHBondContact O-N 2.94Å; L57-N61 VanDerWaalsContact O-N 3.08Å; L57-N61 PolarHBondContact O-ND2 3.06Å; L57-F66 HydrophobicContact CB-CE1 4.12Å; L57-F66 HydrophobicContact CB-CZ 4Å; L57-D293 HydrophobicContact CD2-CB 4.34Å; L57-Q297 HydrophobicContact CD1-CB 3.75Å; L57-Q297 HydrophobicContact CD1-CG 3.98Å; L57-Q297 VanDerWaalsContact CD1-OE1 3.29Å
58	C	89.8	Confident	89	Confident	0 Å²	0	20.2 Å²	20.2	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-60.2	-50	179	-165.8	0	0	0	0	111.2	F54 P55 Y56 G63 F66 M67 Y277	F54-C58 WeakPolarHBondContact O-CB 3.19Å; F54-C58 PolarHBondContact O-N 3.11Å; P55-C58 PolarHBondContact O-N 3.23Å; Y56-C58 VanDerWaalsContact C-N 3.29Å; Y56-C58 PolarHBondContact O-N 3.09Å; C58-G63 WeakPolarHBondContact O-CA 3.43Å; C58-G63 PolarHBondContact O-N 2.87Å; C58-G63 PolarHBondContact SG-O 3.42Å; C58-F66 HydrophobicContact CB-CD1 4.04Å; C58-M67 WeakPolarHBondContact SG-CE 3.5Å; C58-Y277 HydrophobicContact CB-CD2 4.22Å; C58-Y277 HydrophobicContact CB-CE2 3.77Å; C58-Y277 WeakPolarHBondContact SG-CE2 3.13Å
59	Y	84.9	Confident	89.2	Confident	39 Å²	39	20.1 Å²	20.1	15%	0.153	10%	0.098	C	C	.	.	H	α-helix	trans	-69.6	-43.6	-179.2	86.5	-105.3	0	0	0	111.9	P55 Y56 N61 G62 Y276 F348 A366	P55-Y59 WeakPolarHBondContact O-CD1 3.48Å; P55-Y59 PolarHBondContact O-N 3.19Å; Y56-Y59 VanDerWaalsContact CA-CD1 3.45Å; Y56-Y59 HydrophobicContact CD2-CD1 4.37Å; Y56-Y59 AromaticContact CD2-CE1 3.33Å; Y56-Y59 HydrophobicContact CD2-CE1 3.33Å; Y56-Y59 AromaticContact CD2-CZ 3.52Å; Y56-Y59 VanDerWaalsContact CD2-OH 3.24Å; Y56-Y59 WeakPolarHBondContact CD2-OH 3.26Å; Y56-Y59 AromaticContact CE2-CE1 3.99Å; Y56-Y59 HydrophobicContact CE2-CE1 3.99Å; Y56-Y59 AromaticContact CE2-CZ 3.66Å; Y56-Y59 WeakPolarHBondContact CE2-OH 3.16Å; Y56-Y59 HydrophobicContact CG-CE1 4.01Å; Y56-Y59 WeakPolarHBondContact O-CD1 3.32Å; Y56-Y59 WeakPolarHBondContact O-CE1 3.49Å; Y56-Y59 PolarHBondContact O-N 2.99Å; Y59-N61 PolarHBondContact O-N 3.39Å; Y59-G62 PolarHBondContact O-N 3.12Å; Y59-Y276 AromaticContact CD2-CE1 3.98Å; Y59-Y276 HydrophobicContact CD2-CE1 3.98Å; Y59-Y276 HydrophobicContact CG-CE1 4.11Å; Y59-F348 HydrophobicContact CD1-CE1 4.45Å; Y59-F348 AromaticContact CD1-CZ 3.71Å; Y59-F348 HydrophobicContact CD1-CZ 3.71Å; Y59-F348 HydrophobicContact CG-CZ 4.09Å; Y59-A366 HydrophobicContact CE1-CB 3.91Å; Y59-A366 PolarHBondContact OH-O 3.06Å
60	R	85.7	Confident	89.5	Confident	90 Å²	90	19.2 Å²	19.2	34%	0.34	9%	0.088	S	C	.	.	H	α-helix	trans	-60.7	-33.6	-177	-170.8	178.7	104.6	175.8	-2.7	112.1	Y56 K289 D293	Y56-R60 WeakPolarHBondContact O-CB 3.43Å; Y56-R60 PolarHBondContact O-N 3.18Å; Y56-R60 VanDerWaalsContact OH-CD 3.26Å; Y56-R60 WeakPolarHBondContact OH-CD 3.31Å; Y56-R60 PolarHBondContact OH-NH1 3.08Å; R60-K289 VanDerWaalsContact NH2-CE 3.32Å; R60-D293 IonicContact CZ-OD2 2.68Å; R60-D293 IonicContact NH2-OD2 3.08Å; R60-D293 PolarHBondContact NH2-OD2 2.97Å
61	N	89.3	Confident	89.6	Confident	8 Å²	8	23.6 Å²	23.6	4%	0.043	11%	0.107	C	C	.	.	T	Hydrogen-bonded Turn	trans	-102.2	23.7	-174.4	-64.6	-30.8	0	0	0	113.6	L57 Y59 F66 V290 D293	L57-N61 VanDerWaalsContact O-CB 3.24Å; L57-N61 WeakPolarHBondContact O-CB 3.48Å; L57-N61 PolarHBondContact O-N 2.94Å; L57-N61 VanDerWaalsContact O-N 3.08Å; L57-N61 PolarHBondContact O-ND2 3.06Å; Y59-N61 PolarHBondContact O-N 3.39Å; N61-F66 HydrophobicContact CB-CB 4.28Å; N61-F66 HydrophobicContact CB-CD2 3.44Å; N61-F66 VanDerWaalsContact CB-CD2 3.44Å; N61-F66 HydrophobicContact CB-CE2 4Å; N61-F66 HydrophobicContact CB-CG 4.08Å; N61-V290 HydrophobicContact CB-CB 4.42Å; N61-V290 HydrophobicContact CB-CG1 4.07Å; N61-V290 HydrophobicContact CB-CG2 3.86Å; N61-D293 VanDerWaalsContact ND2-CB 3.29Å; N61-D293 WeakPolarHBondContact ND2-CB 3.47Å; N61-D293 PolarHBondContact ND2-OD2 3.39Å; N61-D293 PolarHBondContact OD1-OD2 2.94Å
62	G	86.8	Confident	89.9	Confident	0 Å²	0	26 Å²	26	0%	0	12%	0.12	C	C	.	.	T	Hydrogen-bonded Turn	trans	103.5	28.5	168.6	0	0	0	0	0	115.5	Y59 G64 A65 Q281	Y59-G62 PolarHBondContact O-N 3.12Å; G62-G64 PolarHBondContact O-N 3.11Å; G62-A65 WeakPolarHBondContact O-CB 3.46Å; G62-A65 PolarHBondContact O-N 2.97Å; G62-A65 VanDerWaalsContact O-N 3.15Å; G62-Q281 PolarHBondContact O-N 2.87Å
63	G	89.9	Confident	90.4	Very high	3 Å²	3	25.3 Å²	25.3	3%	0.031	12%	0.117	C	C	.	.	G	3₁₀ helix	trans	58.8	-128.4	175.4	0	0	0	0	0	111.7	C58 A65 F66 Y277	C58-G63 WeakPolarHBondContact O-CA 3.43Å; C58-G63 PolarHBondContact O-N 2.87Å; C58-G63 PolarHBondContact SG-O 3.42Å; G63-A65 PolarHBondContact O-N 2.87Å; G63-F66 WeakPolarHBondContact O-CB 3.44Å; G63-F66 PolarHBondContact O-N 3.47Å; G63-Y277 CarbonylContact C-O 3.59Å; G63-Y277 VanDerWaalsContact C-O 3.29Å; G63-Y277 WeakPolarHBondContact CA-O 3.4Å
64	G	90.1	Very high	90.7	Very high	17 Å²	17	22.8 Å²	22.8	18%	0.175	11%	0.109	C	C	.	.	G	3₁₀ helix	trans	-58.4	-22	179.7	0	0	0	0	0	114.6	G62 F66 M67 Y277 L278	G62-G64 PolarHBondContact O-N 3.11Å; G64-F66 VanDerWaalsContact C-N 3.29Å; G64-F66 PolarHBondContact O-N 3.09Å; G64-M67 WeakPolarHBondContact O-CB 3.38Å; G64-M67 WeakPolarHBondContact O-CG 3.43Å; G64-M67 PolarHBondContact O-N 3.01Å; G64-Y277 PolarHBondContact N-O 3.47Å; G64-Y277 VanDerWaalsContact N-O 3.16Å; G64-L278 WeakPolarHBondContact CA-O 3.49Å; G64-L278 PolarHBondContact N-O 3.21Å
65	A	93.1	Very high	90.7	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	13%	0.126	C	C	.	.	G	3₁₀ helix	trans	-69	-27.1	177.5	0	0	0	0	0	112.5	G62 G63 M67 L68 P69 P280 W282 V285	G62-A65 WeakPolarHBondContact O-CB 3.46Å; G62-A65 PolarHBondContact O-N 2.97Å; G62-A65 VanDerWaalsContact O-N 3.15Å; G63-A65 PolarHBondContact O-N 2.87Å; A65-M67 PolarHBondContact O-N 3.39Å; A65-L68 PolarHBondContact O-N 3.32Å; A65-P69 WeakPolarHBondContact O-CD 3.35Å; A65-P280 HydrophobicContact CB-CB 3.99Å; A65-W282 HydrophobicContact CB-CD2 4.48Å; A65-W282 HydrophobicContact CB-CE3 4.17Å; A65-W282 HydrophobicContact CB-CZ3 4.47Å; A65-V285 HydrophobicContact CB-CG2 3.69Å; A65-V285 WeakPolarHBondContact O-CG2 3.38Å
66	F	93.9	Very high	90.9	Very high	0 Å²	0	29 Å²	29	0%	0	14%	0.141	C	C	.	.	G	3₁₀ helix	trans	-65.2	-24.6	175.1	179.8	-107.2	0	0	0	113.1	F54 L57 C58 N61 G63 G64 L68 P69 Y70 V290 D293 A294	F54-F66 HydrophobicContact CE2-CE1 4.21Å; L57-F66 HydrophobicContact CB-CE1 4.12Å; L57-F66 HydrophobicContact CB-CZ 4Å; C58-F66 HydrophobicContact CB-CD1 4.04Å; N61-F66 HydrophobicContact CB-CB 4.28Å; N61-F66 HydrophobicContact CB-CD2 3.44Å; N61-F66 VanDerWaalsContact CB-CD2 3.44Å; N61-F66 HydrophobicContact CB-CE2 4Å; N61-F66 HydrophobicContact CB-CG 4.08Å; G63-F66 WeakPolarHBondContact O-CB 3.44Å; G63-F66 PolarHBondContact O-N 3.47Å; G64-F66 VanDerWaalsContact C-N 3.29Å; G64-F66 PolarHBondContact O-N 3.09Å; F66-L68 PolarHBondContact O-N 2.72Å; F66-P69 WeakPolarHBondContact O-CD 3.25Å; F66-P69 VanDerWaalsContact O-CG 3.26Å; F66-P69 WeakPolarHBondContact O-CG 3.42Å; F66-Y70 HydrophobicContact CE1-CD2 4.37Å; F66-Y70 VanDerWaalsContact O-CB 3.3Å; F66-Y70 WeakPolarHBondContact O-CB 3.34Å; F66-Y70 PolarHBondContact O-N 3.26Å; F66-Y70 VanDerWaalsContact O-N 3.14Å; F66-V290 HydrophobicContact CD2-CG1 3.92Å; F66-D293 HydrophobicContact CE2-CB 4.41Å; F66-A294 HydrophobicContact CD2-CB 4.49Å; F66-A294 HydrophobicContact CE2-CB 3.68Å; F66-A294 HydrophobicContact CZ-CB 3.93Å
67	M	91.9	Very high	91.1	Very high	21 Å²	21	27.3 Å²	27.3	10%	0.103	13%	0.134	C	C	.	.	H	α-helix	trans	-62.2	-33.3	179.2	-62.3	-61.7	-176.8	0	0	112.1	F54 C58 G64 A65 Y70 F71 Y277 V341	F54-M67 HydrophobicContact CE1-CE 3.88Å; F54-M67 HydrophobicContact CE1-SD 4.38Å; F54-M67 HydrophobicContact CZ-CE 3.73Å; F54-M67 HydrophobicContact CZ-SD 3.63Å; C58-M67 WeakPolarHBondContact SG-CE 3.5Å; G64-M67 WeakPolarHBondContact O-CB 3.38Å; G64-M67 WeakPolarHBondContact O-CG 3.43Å; G64-M67 PolarHBondContact O-N 3.01Å; A65-M67 PolarHBondContact O-N 3.39Å; M67-Y70 PolarHBondContact O-N 3.5Å; M67-F71 HydrophobicContact CB-CD2 4.17Å; M67-F71 HydrophobicContact CB-CE2 3.84Å; M67-F71 WeakPolarHBondContact O-CB 3.25Å; M67-F71 WeakPolarHBondContact O-CD2 3.36Å; M67-F71 VanDerWaalsContact O-CG 3.32Å; M67-F71 WeakPolarHBondContact O-CG 3.49Å; M67-F71 PolarHBondContact O-N 3.15Å; M67-Y277 HydrophobicContact CE-CE1 4.48Å; M67-Y277 HydrophobicContact CE-CE2 3.74Å; M67-Y277 WeakPolarHBondContact CE-OH 3.19Å; M67-V341 HydrophobicContact CE-CG1 4.46Å; M67-V341 HydrophobicContact CE-CG2 4.14Å; M67-V341 HydrophobicContact SD-CG2 4.09Å
68	L	93.1	Very high	91.3	Very high	81 Å²	81	26.8 Å²	26.8	42%	0.424	13%	0.132	S	C	.	.	H	α-helix	trans	-62.2	-59.7	178.8	178.2	68.9	0	0	0	112.5	A65 F66 Y70 F71 I72 W282	A65-L68 PolarHBondContact O-N 3.32Å; F66-L68 PolarHBondContact O-N 2.72Å; L68-Y70 PolarHBondContact O-N 3.36Å; L68-F71 PolarHBondContact O-N 2.92Å; L68-I72 HydrophobicContact CD1-CD1 3.87Å; L68-I72 HydrophobicContact CD1-CG1 4.45Å; L68-I72 HydrophobicContact CG-CD1 3.95Å; L68-I72 VanDerWaalsContact O-CG1 3.3Å; L68-I72 WeakPolarHBondContact O-CG1 3.34Å; L68-I72 PolarHBondContact O-N 2.95Å; L68-W282 HydrophobicContact CD2-CZ3 4.2Å
69	P	93.1	Very high	91.5	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-61.6	-34.4	176.9	23.1	-32.1	0	0	0	111.9	A65 F66 I72 M73 V290 W291 A294	A65-P69 WeakPolarHBondContact O-CD 3.35Å; F66-P69 WeakPolarHBondContact O-CD 3.25Å; F66-P69 VanDerWaalsContact O-CG 3.26Å; F66-P69 WeakPolarHBondContact O-CG 3.42Å; P69-I72 PolarHBondContact O-N 2.63Å; P69-M73 WeakPolarHBondContact O-CB 3.4Å; P69-M73 WeakPolarHBondContact O-CG 3.35Å; P69-M73 PolarHBondContact O-N 2.97Å; P69-V290 HydrophobicContact CG-CG1 3.88Å; P69-W291 HydrophobicContact CB-CD2 3.63Å; P69-W291 HydrophobicContact CB-CE3 3.48Å; P69-W291 VanDerWaalsContact CB-CE3 3.48Å; P69-W291 HydrophobicContact CB-CG 4.27Å; P69-W291 HydrophobicContact CB-CH2 4.06Å; P69-W291 HydrophobicContact CB-CZ2 4.16Å; P69-W291 HydrophobicContact CB-CZ3 3.72Å; P69-A294 HydrophobicContact CB-CB 4.04Å; P69-A294 HydrophobicContact CG-CB 4.44Å
70	Y	93.6	Very high	91.9	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-60.8	-49.2	175.4	-179.7	-105.8	0	0	0	112.9	F54 F66 M67 L68 M73 L74 Q297 I298 C337	F54-Y70 HydrophobicContact CD2-CD2 4.39Å; F54-Y70 HydrophobicContact CD2-CE1 4.36Å; F54-Y70 AromaticContact CD2-CE2 3.88Å; F54-Y70 HydrophobicContact CD2-CE2 3.88Å; F54-Y70 AromaticContact CD2-CZ 3.85Å; F54-Y70 AromaticContact CE2-CD1 3.76Å; F54-Y70 HydrophobicContact CE2-CD1 3.76Å; F54-Y70 AromaticContact CE2-CD2 3.88Å; F54-Y70 HydrophobicContact CE2-CD2 3.88Å; F54-Y70 AromaticContact CE2-CE1 3.5Å; F54-Y70 HydrophobicContact CE2-CE1 3.5Å; F54-Y70 AromaticContact CE2-CE2 3.64Å; F54-Y70 HydrophobicContact CE2-CE2 3.64Å; F54-Y70 AromaticContact CE2-CG 3.92Å; F54-Y70 HydrophobicContact CE2-CG 3.92Å; F54-Y70 AromaticContact CE2-CZ 3.43Å; F54-Y70 VanDerWaalsContact CE2-CZ 3.43Å; F54-Y70 HydrophobicContact CZ-CD1 4.27Å; F54-Y70 HydrophobicContact CZ-CE1 4.06Å; F66-Y70 HydrophobicContact CE1-CD2 4.37Å; F66-Y70 VanDerWaalsContact O-CB 3.3Å; F66-Y70 WeakPolarHBondContact O-CB 3.34Å; F66-Y70 PolarHBondContact O-N 3.26Å; F66-Y70 VanDerWaalsContact O-N 3.14Å; M67-Y70 PolarHBondContact O-N 3.5Å; L68-Y70 PolarHBondContact O-N 3.36Å; Y70-M73 PolarHBondContact O-N 3.31Å; Y70-L74 WeakPolarHBondContact O-CB 3.27Å; Y70-L74 PolarHBondContact O-N 3.25Å; Y70-Q297 HydrophobicContact CD2-CG 4.45Å; Y70-Q297 HydrophobicContact CE2-CB 4.44Å; Y70-Q297 HydrophobicContact CE2-CG 3.89Å; Y70-I298 HydrophobicContact CD2-CD1 3.64Å; Y70-I298 HydrophobicContact CD2-CG1 3.82Å; Y70-I298 HydrophobicContact CE1-CD1 4.23Å; Y70-I298 HydrophobicContact CE2-CD1 3.19Å; Y70-I298 HydrophobicContact CE2-CG1 3.74Å; Y70-I298 HydrophobicContact CG-CD1 4.31Å; Y70-C337 HydrophobicContact CE1-CB 3.96Å; Y70-C337 PolarHBondContact OH-SG 2.96Å
71	F	93.9	Very high	92.2	Very high	94 Å²	94	21.5 Å²	21.5	41%	0.412	11%	0.112	S	C	.	.	H	α-helix	trans	-69.4	-34.5	178.2	-68	-46.3	0	0	0	113	M67 L68 L74 V75 V341	M67-F71 HydrophobicContact CB-CD2 4.17Å; M67-F71 HydrophobicContact CB-CE2 3.84Å; M67-F71 WeakPolarHBondContact O-CB 3.25Å; M67-F71 WeakPolarHBondContact O-CD2 3.36Å; M67-F71 VanDerWaalsContact O-CG 3.32Å; M67-F71 WeakPolarHBondContact O-CG 3.49Å; M67-F71 PolarHBondContact O-N 3.15Å; L68-F71 PolarHBondContact O-N 2.92Å; F71-L74 HydrophobicContact CD1-CD2 4.36Å; F71-L74 WeakPolarHBondContact O-CB 3.29Å; F71-L74 PolarHBondContact O-N 3.23Å; F71-V75 WeakPolarHBondContact O-CG2 3.08Å; F71-V75 PolarHBondContact O-N 3.5Å; F71-V341 HydrophobicContact CZ-CG2 4.31Å
72	I	93.7	Very high	92.4	Very high	54 Å²	54	21.1 Å²	21.1	28%	0.277	11%	0.11	S	C	.	.	H	α-helix	trans	-62.7	-47.1	173.7	-68.9	168.9	0	0	0	109.9	L68 P69 L74 V75 F76 W291	L68-I72 HydrophobicContact CD1-CD1 3.87Å; L68-I72 HydrophobicContact CD1-CG1 4.45Å; L68-I72 HydrophobicContact CG-CD1 3.95Å; L68-I72 VanDerWaalsContact O-CG1 3.3Å; L68-I72 WeakPolarHBondContact O-CG1 3.34Å; L68-I72 PolarHBondContact O-N 2.95Å; P69-I72 PolarHBondContact O-N 2.63Å; I72-L74 VanDerWaalsContact C-N 3.31Å; I72-L74 PolarHBondContact O-N 2.94Å; I72-V75 PolarHBondContact O-N 3.12Å; I72-F76 HydrophobicContact CG2-CD2 3.86Å; I72-F76 HydrophobicContact CG2-CE2 4.3Å; I72-F76 WeakPolarHBondContact O-CD2 3.27Å; I72-F76 PolarHBondContact O-N 3.47Å; I72-W291 HydrophobicContact CB-CZ3 4.19Å; I72-W291 HydrophobicContact CD1-CH2 3.72Å; I72-W291 HydrophobicContact CD1-CZ3 4.05Å; I72-W291 HydrophobicContact CG2-CZ3 4Å
73	M	92.4	Very high	92.7	Very high	12 Å²	12	21.1 Å²	21.1	6%	0.059	11%	0.11	C	C	.	.	H	α-helix	trans	-63.7	-36.4	177.2	-70.4	-64.1	170.8	0	0	112.3	P69 Y70 C77 G78 W291 A294 A295 I298 I516	P69-M73 WeakPolarHBondContact O-CB 3.4Å; P69-M73 WeakPolarHBondContact O-CG 3.35Å; P69-M73 PolarHBondContact O-N 2.97Å; Y70-M73 PolarHBondContact O-N 3.31Å; M73-C77 WeakPolarHBondContact O-CA 3.16Å; M73-C77 VanDerWaalsContact O-CB 3.32Å; M73-C77 WeakPolarHBondContact O-CB 3.27Å; M73-C77 PolarHBondContact O-N 3.21Å; M73-G78 PolarHBondContact O-N 3.24Å; M73-W291 HydrophobicContact CE-CB 4.48Å; M73-W291 HydrophobicContact CE-CE3 3.71Å; M73-W291 HydrophobicContact CE-CZ3 4.4Å; M73-A294 HydrophobicContact CG-CB 4.5Å; M73-A295 HydrophobicContact CE-CB 4.39Å; M73-A295 HydrophobicContact CG-CB 3.98Å; M73-A295 HydrophobicContact SD-CB 3.82Å; M73-I298 HydrophobicContact CB-CG1 4.09Å; M73-I516 HydrophobicContact CE-CG2 4Å; M73-I516 HydrophobicContact SD-CG2 3.66Å
74	L	93.8	Very high	92.8	Very high	10 Å²	10	21 Å²	21	5%	0.052	11%	0.109	C	C	.	.	I	π-helix	trans	-60.5	-51	172.7	178.6	62.4	0	0	0	112	Y70 F71 I72 G78 I79 I298 L302 C337	Y70-L74 WeakPolarHBondContact O-CB 3.27Å; Y70-L74 PolarHBondContact O-N 3.25Å; F71-L74 HydrophobicContact CD1-CD2 4.36Å; F71-L74 WeakPolarHBondContact O-CB 3.29Å; F71-L74 PolarHBondContact O-N 3.23Å; I72-L74 VanDerWaalsContact C-N 3.31Å; I72-L74 PolarHBondContact O-N 2.94Å; L74-G78 CarbonylContact O-C 3.29Å; L74-G78 WeakPolarHBondContact O-CA 3.29Å; L74-G78 PolarHBondContact O-N 2.67Å; L74-I79 HydrophobicContact CD1-CD1 4.4Å; L74-I79 HydrophobicContact CD1-CG1 3.92Å; L74-I79 HydrophobicContact CG-CD1 4.08Å; L74-I79 HydrophobicContact CG-CG1 4.1Å; L74-I79 PolarHBondContact O-N 3.24Å; L74-I298 HydrophobicContact CB-CD1 3.76Å; L74-I298 HydrophobicContact CD1-CD1 4.06Å; L74-I298 HydrophobicContact CG-CD1 4.45Å; L74-L302 HydrophobicContact CD1-CD1 4.09Å; L74-C337 WeakPolarHBondContact CD1-SG 3.43Å; L74-C337 HydrophobicContact CD2-CB 3.82Å; L74-C337 WeakPolarHBondContact CD2-SG 3.36Å
75	V	93.8	Very high	93	Very high	59 Å²	59	20.2 Å²	20.2	36%	0.358	10%	0.101	S	C	.	.	I	π-helix	trans	-68.1	-44.4	-174.3	170	0	0	0	0	111.4	F71 I72 P80 F504	F71-V75 WeakPolarHBondContact O-CG2 3.08Å; F71-V75 PolarHBondContact O-N 3.5Å; I72-V75 PolarHBondContact O-N 3.12Å; V75-P80 WeakPolarHBondContact O-CD 3.17Å; V75-P80 WeakPolarHBondContact O-CG 3.38Å; V75-F504 HydrophobicContact CG1-CE2 4.28Å; V75-F504 HydrophobicContact CG1-CZ 3.76Å; V75-F504 VanDerWaalsContact O-CZ 3.32Å; V75-F504 WeakPolarHBondContact O-CZ 3.39Å
76	F	92.6	Very high	92.9	Very high	73 Å²	73	20.2 Å²	20.2	32%	0.32	10%	0.101	S	C	.	.	I	π-helix	trans	-94.7	-18.1	-171.7	-69.5	-72.9	0	0	0	114.9	I72 F504 I512 S513 I516	I72-F76 HydrophobicContact CG2-CD2 3.86Å; I72-F76 HydrophobicContact CG2-CE2 4.3Å; I72-F76 WeakPolarHBondContact O-CD2 3.27Å; I72-F76 PolarHBondContact O-N 3.47Å; F76-F504 HydrophobicContact CD1-CE2 4.22Å; F76-F504 HydrophobicContact CD1-CZ 4.45Å; F76-F504 HydrophobicContact CE1-CE2 4.03Å; F76-I512 HydrophobicContact CB-CG2 3.87Å; F76-I512 HydrophobicContact CD1-CD1 3.86Å; F76-I512 HydrophobicContact CD1-CG2 4.05Å; F76-I512 HydrophobicContact CE1-CD1 4.15Å; F76-I512 HydrophobicContact CG-CG2 4.26Å; F76-S513 PolarHBondContact O-OG 3.14Å; F76-I516 HydrophobicContact CB-CD1 4.08Å
77	C	90.6	Very high	92.8	Very high	1 Å²	1	20.2 Å²	20.2	1%	0.007	10%	0.101	C	C	.	.	I	π-helix	trans	-123	-55.3	177.1	-71.1	0	0	0	0	112.6	M73 P80 L81 I516	M73-C77 WeakPolarHBondContact O-CA 3.16Å; M73-C77 VanDerWaalsContact O-CB 3.32Å; M73-C77 WeakPolarHBondContact O-CB 3.27Å; M73-C77 PolarHBondContact O-N 3.21Å; C77-P80 WeakPolarHBondContact O-CD 3.26Å; C77-L81 HydrophobicContact CB-CD1 4.42Å; C77-L81 VanDerWaalsContact O-CB 3.3Å; C77-L81 WeakPolarHBondContact O-CB 3.39Å; C77-L81 WeakPolarHBondContact O-CD1 3.32Å; C77-L81 WeakPolarHBondContact O-CG 3.37Å; C77-L81 PolarHBondContact O-N 3.03Å; C77-I516 WeakPolarHBondContact SG-CB 3.25Å; C77-I516 WeakPolarHBondContact SG-CG2 3.46Å
78	G	92.1	Very high	92.8	Very high	1 Å²	1	19.3 Å²	19.3	1%	0.01	10%	0.096	C	C	.	.	I	π-helix	trans	-55.8	-65	-174.2	0	0	0	0	0	113.4	M73 L74 L81 F82 L302	M73-G78 PolarHBondContact O-N 3.24Å; L74-G78 CarbonylContact O-C 3.29Å; L74-G78 WeakPolarHBondContact O-CA 3.29Å; L74-G78 PolarHBondContact O-N 2.67Å; G78-L81 PolarHBondContact O-N 3.31Å; G78-F82 VanDerWaalsContact O-CB 3.27Å; G78-F82 WeakPolarHBondContact O-CB 3.39Å; G78-F82 PolarHBondContact O-N 3.46Å; G78-L302 VanDerWaalsContact CA-CD1 3.46Å
79	I	92.9	Very high	92.8	Very high	17 Å²	17	15.4 Å²	15.4	9%	0.087	8%	0.076	C	C	.	.	H	α-helix	trans	-59.8	-46	-177.4	-63.3	171	0	0	0	111.8	L74 F82 F83 I330 F505	L74-I79 HydrophobicContact CD1-CD1 4.4Å; L74-I79 HydrophobicContact CD1-CG1 3.92Å; L74-I79 HydrophobicContact CG-CD1 4.08Å; L74-I79 HydrophobicContact CG-CG1 4.1Å; L74-I79 PolarHBondContact O-N 3.24Å; I79-F82 PolarHBondContact O-N 3.5Å; I79-F83 WeakPolarHBondContact O-CB 3.4Å; I79-F83 PolarHBondContact O-N 3.01Å; I79-I330 HydrophobicContact CG2-CG1 4.05Å; I79-F505 HydrophobicContact CG2-CE1 4.03Å; I79-F505 HydrophobicContact CG2-CZ 4.19Å
80	P	93.5	Very high	92.7	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-58.4	-50.2	175.7	-27.8	36.8	0	0	0	112.7	V75 C77 F82 F83 L84 F504 F505 C508 W509	V75-P80 WeakPolarHBondContact O-CD 3.17Å; V75-P80 WeakPolarHBondContact O-CG 3.38Å; C77-P80 WeakPolarHBondContact O-CD 3.26Å; P80-F82 VanDerWaalsContact C-N 3.35Å; P80-F82 PolarHBondContact O-N 3.27Å; P80-F83 PolarHBondContact O-N 3.39Å; P80-L84 PolarHBondContact O-N 3.12Å; P80-F504 HydrophobicContact CG-CE1 4.23Å; P80-F505 HydrophobicContact CB-CD1 4.38Å; P80-C508 HydrophobicContact CB-CB 3.74Å; P80-C508 HydrophobicContact CG-CB 3.63Å; P80-W509 VanDerWaalsContact C-NE1 3.32Å; P80-W509 PolarHBondContact O-NE1 3.42Å
81	L	92.8	Very high	92.5	Very high	0 Å²	0	15.7 Å²	15.7	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-67.2	-37.8	-177.5	-65.4	171.9	0	0	0	112.2	C77 G78 F83 L84 E85 F299 C477 I517	C77-L81 HydrophobicContact CB-CD1 4.42Å; C77-L81 VanDerWaalsContact O-CB 3.3Å; C77-L81 WeakPolarHBondContact O-CB 3.39Å; C77-L81 WeakPolarHBondContact O-CD1 3.32Å; C77-L81 WeakPolarHBondContact O-CG 3.37Å; C77-L81 PolarHBondContact O-N 3.03Å; G78-L81 PolarHBondContact O-N 3.31Å; L81-F83 VanDerWaalsContact C-N 3.33Å; L81-F83 PolarHBondContact O-N 2.92Å; L81-L84 HydrophobicContact CD2-CD2 4.33Å; L81-L84 WeakPolarHBondContact O-CB 3.36Å; L81-L84 PolarHBondContact O-N 2.87Å; L81-L84 VanDerWaalsContact O-N 3.15Å; L81-E85 PolarHBondContact O-N 3.04Å; L81-F299 HydrophobicContact CD1-CE1 3.46Å; L81-F299 VanDerWaalsContact CD1-CE1 3.46Å; L81-F299 HydrophobicContact CD1-CZ 3.39Å; L81-C477 WeakPolarHBondContact CD2-SG 3.43Å; L81-I517 HydrophobicContact CD1-CD1 3.61Å; L81-I517 HydrophobicContact CD1-CG1 4.34Å; L81-I517 HydrophobicContact CD2-CD1 4.13Å; L81-I517 HydrophobicContact CG-CD1 4.48Å
82	F	92.9	Very high	92.3	Very high	0 Å²	0	11.2 Å²	11.2	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-58	-47.2	173.7	-162.6	-87.6	0	0	0	111.1	G78 I79 P80 L84 E85 L86 L302 L309 I332	G78-F82 VanDerWaalsContact O-CB 3.27Å; G78-F82 WeakPolarHBondContact O-CB 3.39Å; G78-F82 PolarHBondContact O-N 3.46Å; I79-F82 PolarHBondContact O-N 3.5Å; P80-F82 VanDerWaalsContact C-N 3.35Å; P80-F82 PolarHBondContact O-N 3.27Å; F82-L84 VanDerWaalsContact C-N 3.33Å; F82-L84 PolarHBondContact O-N 3.42Å; F82-E85 PolarHBondContact O-N 3.26Å; F82-L86 HydrophobicContact CD1-CD1 3.7Å; F82-L86 HydrophobicContact CD1-CG 4.12Å; F82-L86 HydrophobicContact CE1-CD1 3.46Å; F82-L86 VanDerWaalsContact CE1-CD1 3.46Å; F82-L86 HydrophobicContact CE1-CG 4.03Å; F82-L86 WeakPolarHBondContact O-CG 3.37Å; F82-L86 PolarHBondContact O-N 3.26Å; F82-L86 VanDerWaalsContact O-N 3.08Å; F82-L302 HydrophobicContact CD2-CB 4.04Å; F82-L302 HydrophobicContact CD2-CD2 4.12Å; F82-L302 HydrophobicContact CD2-CG 4.46Å; F82-L302 HydrophobicContact CE2-CB 4.46Å; F82-L302 HydrophobicContact CE2-CD2 4.31Å; F82-L309 HydrophobicContact CD2-CD1 3.33Å; F82-L309 HydrophobicContact CD2-CD2 4.15Å; F82-L309 HydrophobicContact CD2-CG 4.38Å; F82-L309 HydrophobicContact CE1-CD2 4.38Å; F82-L309 HydrophobicContact CE2-CD1 3.46Å; F82-L309 VanDerWaalsContact CE2-CD1 3.46Å; F82-L309 HydrophobicContact CE2-CD2 3.36Å; F82-L309 HydrophobicContact CE2-CG 4.04Å; F82-L309 HydrophobicContact CG-CD1 4Å; F82-L309 HydrophobicContact CZ-CD1 4.19Å; F82-L309 HydrophobicContact CZ-CD2 3.48Å; F82-L309 VanDerWaalsContact CZ-CD2 3.48Å; F82-L309 HydrophobicContact CZ-CG 4.48Å; F82-I332 HydrophobicContact CE1-CB 4.05Å; F82-I332 HydrophobicContact CE1-CD1 4.1Å; F82-I332 HydrophobicContact CE1-CG2 3.98Å; F82-I332 HydrophobicContact CE2-CG2 4.31Å; F82-I332 HydrophobicContact CZ-CB 4.1Å; F82-I332 HydrophobicContact CZ-CD1 4.42Å; F82-I332 HydrophobicContact CZ-CG2 3.49Å; F82-I332 VanDerWaalsContact CZ-CG2 3.49Å
83	F	92.8	Very high	92.1	Very high	0 Å²	0	9.2 Å²	9.2	0%	0	5%	0.049	C	C	.	.	H	α-helix	trans	-66.1	-35.2	176.2	-178.9	-132.7	0	0	0	112.7	I79 P80 L81 S87 T325 H326 V493 L497 F505 W509	I79-F83 WeakPolarHBondContact O-CB 3.4Å; I79-F83 PolarHBondContact O-N 3.01Å; P80-F83 PolarHBondContact O-N 3.39Å; L81-F83 VanDerWaalsContact C-N 3.33Å; L81-F83 PolarHBondContact O-N 2.92Å; F83-S87 WeakPolarHBondContact O-CB 3.32Å; F83-S87 PolarHBondContact O-N 2.85Å; F83-S87 PolarHBondContact O-OG 3.49Å; F83-T325 HydrophobicContact CE2-CG2 4.31Å; F83-H326 HydrophobicContact CE2-CB 4.21Å; F83-H326 HydrophobicContact CZ-CB 4.31Å; F83-V493 HydrophobicContact CZ-CG1 4.38Å; F83-L497 HydrophobicContact CE2-CD1 4.24Å; F83-L497 HydrophobicContact CZ-CD1 3.77Å; F83-F505 HydrophobicContact CB-CD1 4.39Å; F83-F505 HydrophobicContact CB-CE1 4.09Å; F83-F505 AromaticContact CD1-CD1 3.55Å; F83-F505 HydrophobicContact CD1-CD1 3.55Å; F83-F505 AromaticContact CD1-CE1 3.79Å; F83-F505 HydrophobicContact CD1-CE1 3.79Å; F83-F505 AromaticContact CD1-CG 3.95Å; F83-F505 HydrophobicContact CD1-CG 3.95Å; F83-F505 HydrophobicContact CD1-CZ 4.43Å; F83-F505 HydrophobicContact CE1-CD1 4.33Å; F83-F505 HydrophobicContact CE1-CG 4.28Å; F83-F505 HydrophobicContact CG-CD1 4.4Å; F83-F505 HydrophobicContact CG-CE1 4.28Å; F83-W509 HydrophobicContact CB-CZ2 4.22Å; F83-W509 AromaticContact CD1-CH2 3.42Å; F83-W509 HydrophobicContact CD1-CH2 3.42Å; F83-W509 VanDerWaalsContact CD1-CH2 3.42Å; F83-W509 AromaticContact CD1-CZ2 3.19Å; F83-W509 HydrophobicContact CD1-CZ2 3.19Å; F83-W509 AromaticContact CE1-CH2 3.37Å; F83-W509 HydrophobicContact CE1-CH2 3.37Å; F83-W509 AromaticContact CE1-CZ2 3.71Å; F83-W509 HydrophobicContact CE1-CZ2 3.71Å; F83-W509 HydrophobicContact CE1-CZ3 4.42Å; F83-W509 HydrophobicContact CG-CH2 4.39Å; F83-W509 AromaticContact CG-CZ2 3.94Å; F83-W509 HydrophobicContact CG-CZ2 3.94Å; F83-W509 HydrophobicContact CZ-CH2 4.32Å
84	L	92.9	Very high	91.9	Very high	1 Å²	1	10.2 Å²	10.2	1%	0.005	5%	0.054	C	C	.	.	H	α-helix	trans	-60	-49.7	175.9	-171.1	71.9	0	0	0	110.8	P80 L81 F82 S87 F88 I480 M481 Y489 W509	P80-L84 PolarHBondContact O-N 3.12Å; L81-L84 HydrophobicContact CD2-CD2 4.33Å; L81-L84 WeakPolarHBondContact O-CB 3.36Å; L81-L84 PolarHBondContact O-N 2.87Å; L81-L84 VanDerWaalsContact O-N 3.15Å; F82-L84 VanDerWaalsContact C-N 3.33Å; F82-L84 PolarHBondContact O-N 3.42Å; L84-S87 PolarHBondContact O-N 3.31Å; L84-S87 PolarHBondContact O-OG 3.44Å; L84-S87 VanDerWaalsContact O-OG 3.08Å; L84-F88 WeakPolarHBondContact O-CB 3.33Å; L84-F88 PolarHBondContact O-N 3.47Å; L84-I480 HydrophobicContact CD1-CG2 4.49Å; L84-I480 HydrophobicContact CD2-CD1 4.17Å; L84-I480 HydrophobicContact CG-CD1 4.31Å; L84-M481 HydrophobicContact CD1-CE 3.47Å; L84-M481 VanDerWaalsContact CD1-CE 3.47Å; L84-Y489 HydrophobicContact CD1-CD1 4.35Å; L84-Y489 HydrophobicContact CD1-CE1 3.43Å; L84-Y489 VanDerWaalsContact CD1-CE1 3.43Å; L84-Y489 WeakPolarHBondContact CD1-OH 3.43Å; L84-Y489 PolarHBondContact O-OH 2.91Å; L84-Y489 VanDerWaalsContact O-OH 3.1Å; L84-W509 HydrophobicContact CB-CZ2 4.08Å; L84-W509 HydrophobicContact CD1-CD2 3.92Å; L84-W509 HydrophobicContact CD1-CE3 4.42Å; L84-W509 HydrophobicContact CD1-CG 4.17Å; L84-W509 HydrophobicContact CD1-CZ2 4.05Å
85	E	93.4	Very high	91.7	Very high	0 Å²	0	9.7 Å²	9.7	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-67.8	-41.5	-178.9	-78.2	-176.5	-127.9	0	0	112.9	L81 F82 F88 G89 A305 L309 I310 M476	L81-E85 PolarHBondContact O-N 3.04Å; F82-E85 PolarHBondContact O-N 3.26Å; E85-F88 PolarHBondContact O-N 3.17Å; E85-G89 PolarHBondContact O-N 2.84Å; E85-A305 WeakPolarHBondContact OE1-CA 3.26Å; E85-A305 PolarHBondContact OE1-N 3.23Å; E85-A305 PolarHBondContact OE2-N 2.9Å; E85-L309 HydrophobicContact CB-CB 4Å; E85-L309 HydrophobicContact CB-CD1 4.4Å; E85-I310 HydrophobicContact CB-CG1 3.92Å; E85-I310 HydrophobicContact CG-CD1 4.29Å; E85-I310 HydrophobicContact CG-CG1 4.03Å; E85-M476 HydrophobicContact CG-CE 3.95Å; E85-M476 HydrophobicContact CG-SD 4.03Å
86	L	91.8	Very high	91.6	Very high	0 Å²	0	6.9 Å²	6.9	0%	0	3%	0.034	C	C	.	.	H	α-helix	trans	-61.3	-47.7	176.1	-71.7	-173.8	0	0	0	111.4	F37 F82 F88 Q90 L309 A313 T325	F37-L86 HydrophobicContact CE2-CD2 4.24Å; F37-L86 HydrophobicContact CZ-CD1 4.23Å; F37-L86 HydrophobicContact CZ-CD2 3.88Å; F82-L86 HydrophobicContact CD1-CD1 3.7Å; F82-L86 HydrophobicContact CD1-CG 4.12Å; F82-L86 HydrophobicContact CE1-CD1 3.46Å; F82-L86 VanDerWaalsContact CE1-CD1 3.46Å; F82-L86 HydrophobicContact CE1-CG 4.03Å; F82-L86 WeakPolarHBondContact O-CG 3.37Å; F82-L86 PolarHBondContact O-N 3.26Å; F82-L86 VanDerWaalsContact O-N 3.08Å; L86-F88 VanDerWaalsContact C-N 3.34Å; L86-F88 PolarHBondContact O-N 3.47Å; L86-Q90 VanDerWaalsContact O-CB 3.23Å; L86-Q90 WeakPolarHBondContact O-CB 3.36Å; L86-Q90 PolarHBondContact O-N 2.86Å; L86-L309 HydrophobicContact CD2-CB 4.16Å; L86-L309 HydrophobicContact CD2-CD2 4.48Å; L86-A313 HydrophobicContact CB-CB 4.34Å; L86-A313 HydrophobicContact CD2-CB 3.81Å; L86-A313 WeakPolarHBondContact O-CB 3.42Å; L86-T325 HydrophobicContact CB-CG2 4.49Å
87	S	91.4	Very high	91.6	Very high	1 Å²	1	3.6 Å²	3.6	1%	0.007	2%	0.02	C	C	.	.	H	α-helix	trans	-67.9	-35.5	178.7	56.5	0	0	0	0	112.3	F83 L84 F91 Y489	F83-S87 WeakPolarHBondContact O-CB 3.32Å; F83-S87 PolarHBondContact O-N 2.85Å; F83-S87 PolarHBondContact O-OG 3.49Å; L84-S87 PolarHBondContact O-N 3.31Å; L84-S87 PolarHBondContact O-OG 3.44Å; L84-S87 VanDerWaalsContact O-OG 3.08Å; S87-F91 WeakPolarHBondContact O-CB 3.45Å; S87-F91 PolarHBondContact O-N 3.44Å; S87-Y489 PolarHBondContact OG-OH 3.43Å
88	F	92.1	Very high	91.6	Very high	1 Å²	1	3.8 Å²	3.8	0%	0.004	2%	0.022	C	C	.	.	H	α-helix	trans	-65.1	-44.1	176.7	-174.1	-140.2	0	0	0	112.7	L84 E85 L86 V99 W100 I102 I310 I480 Y489 W587	L84-F88 WeakPolarHBondContact O-CB 3.33Å; L84-F88 PolarHBondContact O-N 3.47Å; E85-F88 PolarHBondContact O-N 3.17Å; L86-F88 VanDerWaalsContact C-N 3.34Å; L86-F88 PolarHBondContact O-N 3.47Å; F88-V99 HydrophobicContact CD1-CB 4.23Å; F88-V99 HydrophobicContact CD1-CG2 4.08Å; F88-V99 HydrophobicContact CE1-CB 3.72Å; F88-V99 HydrophobicContact CE1-CG2 3.44Å; F88-V99 VanDerWaalsContact CE1-CG2 3.44Å; F88-V99 HydrophobicContact CE2-CB 4.06Å; F88-V99 HydrophobicContact CZ-CB 3.61Å; F88-V99 HydrophobicContact CZ-CG2 3.77Å; F88-V99 WeakPolarHBondContact CZ-O 3.36Å; F88-W100 HydrophobicContact CE1-CZ2 4.36Å; F88-I102 HydrophobicContact CE2-CB 4.15Å; F88-I102 HydrophobicContact CE2-CD1 3.84Å; F88-I102 HydrophobicContact CE2-CG2 3.79Å; F88-I102 HydrophobicContact CZ-CB 4.49Å; F88-I102 HydrophobicContact CZ-CG2 3.68Å; F88-I310 HydrophobicContact CD1-CD1 3.99Å; F88-I310 HydrophobicContact CD1-CG1 4.5Å; F88-I310 HydrophobicContact CE1-CD1 4.4Å; F88-I480 HydrophobicContact CD1-CD1 4.14Å; F88-I480 HydrophobicContact CD2-CD1 4.49Å; F88-I480 HydrophobicContact CE1-CD1 4.22Å; F88-I480 HydrophobicContact CG-CD1 4.28Å; F88-I480 HydrophobicContact CZ-CD1 4.44Å; F88-Y489 HydrophobicContact CD2-CE2 4.36Å; F88-W587 AromaticContact CD2-CH2 3.89Å; F88-W587 HydrophobicContact CD2-CH2 3.89Å; F88-W587 HydrophobicContact CD2-CZ2 4.49Å; F88-W587 AromaticContact CE2-CH2 3.44Å; F88-W587 HydrophobicContact CE2-CH2 3.44Å; F88-W587 VanDerWaalsContact CE2-CH2 3.44Å; F88-W587 HydrophobicContact CE2-CZ2 4.11Å; F88-W587 HydrophobicContact CE2-CZ3 4.18Å; F88-W587 HydrophobicContact CZ-CH2 4.48Å
89	G	91.8	Very high	91.6	Very high	0 Å²	0	3.7 Å²	3.7	0%	0	2%	0.021	C	C	.	.	H	α-helix	trans	-69.5	-44.5	176	0	0	0	0	0	113.4	E85 S93	E85-G89 PolarHBondContact O-N 2.84Å; G89-S93 WeakPolarHBondContact O-CA 3.27Å; G89-S93 PolarHBondContact O-N 3.36Å
90	Q	90.9	Very high	91.7	Very high	0 Å²	0	3 Å²	3	0%	0	2%	0.017	C	C	.	.	H	α-helix	trans	-64.9	-44.8	-179.2	-176.1	176	-20.3	0	0	111.9	L86 A92 S93 A313 N316 K317 F318 T325 M496	L86-Q90 VanDerWaalsContact O-CB 3.23Å; L86-Q90 WeakPolarHBondContact O-CB 3.36Å; L86-Q90 PolarHBondContact O-N 2.86Å; Q90-A92 PolarHBondContact O-N 2.77Å; Q90-S93 PolarHBondContact O-N 2.99Å; Q90-S93 PolarHBondContact O-OG 3.09Å; Q90-A313 WeakPolarHBondContact CA-O 3.33Å; Q90-A313 HydrophobicContact CB-CB 4.23Å; Q90-N316 HydrophobicContact CG-CB 3.93Å; Q90-K317 PolarHBondContact NE2-O 2.64Å; Q90-F318 PolarHBondContact NE2-O 3.44Å; Q90-T325 PolarHBondContact OE1-OG1 3.28Å; Q90-M496 HydrophobicContact CB-SD 3.77Å; Q90-M496 HydrophobicContact CG-SD 3.58Å; Q90-M496 VanDerWaalsContact CG-SD 3.58Å
91	F	90.4	Very high	91.6	Very high	6 Å²	6	6.4 Å²	6.4	3%	0.026	3%	0.032	C	C	.	.	H	α-helix	trans	-59	-46.6	-178.3	176.8	-101.2	0	0	0	112.5	S87 F318 D492 M495 M496 W587 P589 Y599	S87-F91 WeakPolarHBondContact O-CB 3.45Å; S87-F91 PolarHBondContact O-N 3.44Å; F91-F318 AromaticContact CD2-CE2 3.93Å; F91-F318 HydrophobicContact CD2-CE2 3.93Å; F91-F318 HydrophobicContact CD2-CZ 4.18Å; F91-F318 HydrophobicContact CE2-CE2 4.3Å; F91-F318 HydrophobicContact CE2-CZ 4.23Å; F91-F318 WeakPolarHBondContact O-CE2 3.44Å; F91-D492 HydrophobicContact CD1-CB 4.43Å; F91-D492 HydrophobicContact CD2-CB 4.08Å; F91-D492 WeakPolarHBondContact CD2-O 3.3Å; F91-D492 HydrophobicContact CE1-CB 4.05Å; F91-D492 HydrophobicContact CE2-CB 3.67Å; F91-D492 HydrophobicContact CG-CB 4.44Å; F91-D492 HydrophobicContact CZ-CB 3.65Å; F91-M495 HydrophobicContact CE2-SD 4.21Å; F91-M496 HydrophobicContact CB-SD 4.14Å; F91-M496 HydrophobicContact CD2-CB 4.38Å; F91-W587 HydrophobicContact CD1-CH2 4.18Å; F91-W587 AromaticContact CD1-CZ2 3.81Å; F91-W587 HydrophobicContact CD1-CZ2 3.81Å; F91-W587 AromaticContact CE1-CZ2 3.86Å; F91-W587 HydrophobicContact CE1-CZ2 3.86Å; F91-P589 HydrophobicContact CE2-CG 4.08Å; F91-P589 HydrophobicContact CZ-CG 4.15Å; F91-Y599 HydrophobicContact CZ-CD2 4.36Å; F91-Y599 AromaticContact CZ-CE2 3.68Å; F91-Y599 HydrophobicContact CZ-CE2 3.68Å; F91-Y599 AromaticContact CZ-CZ 3.9Å
92	A	88.7	Confident	91.6	Very high	0 Å²	0	6.4 Å²	6.4	0%	0	3%	0.032	C	C	.	.	H	α-helix	trans	-81.8	-23.5	-179.5	0	0	0	0	0	112.9	Q90 L94 V99 W587 A590	Q90-A92 PolarHBondContact O-N 2.77Å; A92-L94 HydrophobicContact CB-CB 4.19Å; A92-L94 HydrophobicContact CB-CD1 4.33Å; A92-L94 HydrophobicContact CB-CG 4.29Å; A92-L94 WeakPolarHBondContact O-CG 3.43Å; A92-L94 PolarHBondContact O-N 2.86Å; A92-V99 HydrophobicContact CB-CG1 4.06Å; A92-W587 HydrophobicContact CB-CH2 3.84Å; A92-W587 HydrophobicContact CB-CZ3 3.61Å; A92-A590 WeakPolarHBondContact O-CB 3.46Å
93	S	89.9	Confident	91.6	Very high	12 Å²	12	6.4 Å²	6.4	8%	0.084	3%	0.032	C	C	.	.	T	Hydrogen-bonded Turn	trans	49.3	42.6	-169.1	-43.2	0	0	0	0	112.1	R28 G89 Q90	R28-S93 VanDerWaalsContact CZ-O 3.26Å; R28-S93 PolarHBondContact NE-O 2.9Å; R28-S93 PolarHBondContact NH1-O 3.22Å; G89-S93 WeakPolarHBondContact O-CA 3.27Å; G89-S93 PolarHBondContact O-N 3.36Å; Q90-S93 PolarHBondContact O-N 2.99Å; Q90-S93 PolarHBondContact O-OG 3.09Å
94	L	88.8	Confident	91.5	Very high	32 Å²	32	7 Å²	7	17%	0.168	4%	0.036	C	C	.	.			trans	-126.3	152.8	179.8	-68.7	176.5	0	0	0	110.2	A92 G98 V99 K101 S314	A92-L94 HydrophobicContact CB-CB 4.19Å; A92-L94 HydrophobicContact CB-CD1 4.33Å; A92-L94 HydrophobicContact CB-CG 4.29Å; A92-L94 WeakPolarHBondContact O-CG 3.43Å; A92-L94 PolarHBondContact O-N 2.86Å; L94-G98 WeakPolarHBondContact CD1-O 3.48Å; L94-V99 HydrophobicContact CB-CG1 4.06Å; L94-V99 WeakPolarHBondContact O-CG1 3.4Å; L94-K101 HydrophobicContact CD1-CD 3.89Å; L94-S314 VanDerWaalsContact O-CB 3.29Å; L94-S314 WeakPolarHBondContact O-CB 3.43Å
95	G	90.3	Very high	91.5	Very high	0 Å²	0	8.2 Å²	8.2	0%	0	4%	0.042	C	C	.	.			trans	-70.1	177.4	174.4	0	0	0	0	0	113.1	L97 G98 V99 D419	G95-L97 PolarHBondContact O-N 3.21Å; G95-G98 PolarHBondContact O-N 3.17Å; G95-V99 PolarHBondContact O-N 3.04Å; G95-V99 VanDerWaalsContact O-N 3.11Å; G95-D419 PolarHBondContact N-OD2 3.06Å
96	C	91.9	Very high	91.5	Very high	0 Å²	0	9.5 Å²	9.5	0%	0	5%	0.048	C	C	.	.	T	Hydrogen-bonded Turn	trans	-56.9	-25.4	-173.7	64.8	0	0	0	0	115.2	V99 W100 M113	C96-V99 WeakPolarHBondContact O-CG2 3.31Å; C96-W100 PolarHBondContact O-NE1 2.9Å; C96-M113 HydrophobicContact CB-SD 4.48Å
97	L	92.6	Very high	91.6	Very high	4 Å²	4	10.7 Å²	10.7	2%	0.021	5%	0.053	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.5	-40.6	171.9	-68.2	176.3	0	0	0	113	G95 W100 Y111 M114 A416 E420	G95-L97 PolarHBondContact O-N 3.21Å; L97-W100 PolarHBondContact O-N 2.87Å; L97-Y111 HydrophobicContact CD1-CD1 4.47Å; L97-Y111 HydrophobicContact CD1-CE1 4.13Å; L97-Y111 HydrophobicContact CD2-CD1 3.75Å; L97-Y111 HydrophobicContact CD2-CD2 3.88Å; L97-Y111 HydrophobicContact CD2-CE1 3.99Å; L97-Y111 HydrophobicContact CD2-CE2 4.13Å; L97-Y111 HydrophobicContact CD2-CG 3.69Å; L97-Y111 VanDerWaalsContact CD2-N 3.28Å; L97-M114 HydrophobicContact CD1-SD 4.16Å; L97-A416 HydrophobicContact CD1-CB 3.9Å; L97-A416 HydrophobicContact CG-CB 4.18Å; L97-E420 HydrophobicContact CD1-CB 4.24Å; L97-E420 HydrophobicContact CD1-CG 4.47Å
98	G	89.4	Confident	91.8	Very high	4 Å²	4	10.7 Å²	10.7	4%	0.041	5%	0.053	C	C	.	.	G	3₁₀ helix	trans	-70.7	-31.8	-173.3	0	0	0	0	0	113.4	L94 G95 W100 K101	L94-G98 WeakPolarHBondContact CD1-O 3.48Å; G95-G98 PolarHBondContact O-N 3.17Å; G98-W100 PolarHBondContact O-N 3.2Å; G98-K101 WeakPolarHBondContact O-CB 3.16Å; G98-K101 WeakPolarHBondContact O-CD 3.44Å; G98-K101 VanDerWaalsContact O-CG 3.25Å; G98-K101 WeakPolarHBondContact O-CG 3.47Å; G98-K101 PolarHBondContact O-N 3.38Å
99	V	92.9	Very high	91.9	Very high	0 Å²	0	10.6 Å²	10.6	0%	0	5%	0.052	C	C	.	.	G	3₁₀ helix	trans	-62.6	-24.8	179	-65.7	0	0	0	0	113.5	F88 A92 L94 G95 C96 K101 I102 I310 W587	F88-V99 HydrophobicContact CD1-CB 4.23Å; F88-V99 HydrophobicContact CD1-CG2 4.08Å; F88-V99 HydrophobicContact CE1-CB 3.72Å; F88-V99 HydrophobicContact CE1-CG2 3.44Å; F88-V99 VanDerWaalsContact CE1-CG2 3.44Å; F88-V99 HydrophobicContact CE2-CB 4.06Å; F88-V99 HydrophobicContact CZ-CB 3.61Å; F88-V99 HydrophobicContact CZ-CG2 3.77Å; F88-V99 WeakPolarHBondContact CZ-O 3.36Å; A92-V99 HydrophobicContact CB-CG1 4.06Å; L94-V99 HydrophobicContact CB-CG1 4.06Å; L94-V99 WeakPolarHBondContact O-CG1 3.4Å; G95-V99 PolarHBondContact O-N 3.04Å; G95-V99 VanDerWaalsContact O-N 3.11Å; C96-V99 WeakPolarHBondContact O-CG2 3.31Å; V99-K101 PolarHBondContact O-N 2.81Å; V99-I102 WeakPolarHBondContact O-CG2 3.18Å; V99-I102 PolarHBondContact O-N 2.84Å; V99-I310 HydrophobicContact CB-CG2 4.4Å; V99-I310 HydrophobicContact CG1-CG2 3.63Å; V99-I310 HydrophobicContact CG2-CD1 4.39Å; V99-I310 HydrophobicContact CG2-CG2 3.93Å; V99-W587 WeakPolarHBondContact O-CZ3 3.44Å
100	W	94.6	Very high	92.1	Very high	1 Å²	1	10.6 Å²	10.6	0%	0.004	5%	0.052	C	C	.	.	G	3₁₀ helix	trans	-73.8	5.2	178.3	-63.4	101	0	0	0	114.3	F88 C96 L97 G98 I102 S103 F106 K107 V109 G110 M113 M476 C479	F88-W100 HydrophobicContact CE1-CZ2 4.36Å; C96-W100 PolarHBondContact O-NE1 2.9Å; L97-W100 PolarHBondContact O-N 2.87Å; G98-W100 PolarHBondContact O-N 3.2Å; W100-I102 HydrophobicContact CE3-CG2 4.48Å; W100-I102 PolarHBondContact O-N 2.89Å; W100-S103 CarbonylContact O-C 3.09Å; W100-S103 PolarHBondContact O-N 3.07Å; W100-S103 VanDerWaalsContact O-O 3.07Å; W100-F106 HydrophobicContact CE3-CB 3.87Å; W100-F106 HydrophobicContact CZ3-CB 4.05Å; W100-K107 VanDerWaalsContact CB-CA 3.5Å; W100-K107 HydrophobicContact CB-CB 3.96Å; W100-K107 HydrophobicContact CB-CG 4.05Å; W100-V109 HydrophobicContact CD2-CB 4.17Å; W100-V109 HydrophobicContact CE3-CB 4.39Å; W100-V109 HydrophobicContact CH2-CB 3.75Å; W100-V109 HydrophobicContact CH2-CG1 3.52Å; W100-V109 HydrophobicContact CH2-CG2 4.13Å; W100-V109 HydrophobicContact CZ2-CB 3.51Å; W100-V109 HydrophobicContact CZ2-CG1 3.21Å; W100-V109 HydrophobicContact CZ2-CG2 4.39Å; W100-V109 HydrophobicContact CZ3-CB 4.19Å; W100-V109 HydrophobicContact CZ3-CG1 4.41Å; W100-V109 HydrophobicContact CZ3-CG2 4.29Å; W100-G110 VanDerWaalsContact NE1-CA 3.32Å; W100-G110 VanDerWaalsContact NE1-N 3.19Å; W100-M113 HydrophobicContact CZ2-CE 4.04Å; W100-M113 HydrophobicContact CZ2-SD 4.49Å; W100-M476 HydrophobicContact CH2-CB 3.81Å; W100-M476 HydrophobicContact CH2-CG 3.76Å; W100-M476 HydrophobicContact CZ2-CB 4.43Å; W100-M476 HydrophobicContact CZ2-CG 4.27Å; W100-C479 HydrophobicContact CZ3-CB 4.26Å
101	K	91.3	Very high	92.3	Very high	72 Å²	72	13.8 Å²	13.8	31%	0.313	7%	0.065	S	C	.	.	G	3₁₀ helix	trans	-56.9	-21.3	161.5	-72.4	170.1	-169.8	168.5	0	112.1	L94 G98 V99 S103 H584 W587	L94-K101 HydrophobicContact CD1-CD 3.89Å; G98-K101 WeakPolarHBondContact O-CB 3.16Å; G98-K101 WeakPolarHBondContact O-CD 3.44Å; G98-K101 VanDerWaalsContact O-CG 3.25Å; G98-K101 WeakPolarHBondContact O-CG 3.47Å; G98-K101 PolarHBondContact O-N 3.38Å; V99-K101 PolarHBondContact O-N 2.81Å; K101-S103 PolarHBondContact O-N 3.41Å; K101-H584 HydrophobicContact CB-CB 4.2Å; K101-H584 WeakPolarHBondContact O-CB 3.4Å; K101-H584 PolarHBondContact O-N 3.5Å; K101-W587 HydrophobicContact CB-CB 4.42Å; K101-W587 HydrophobicContact CB-CE3 3.98Å
102	I	92.8	Very high	92.5	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	6%	0.064	C	C	.	.	G	3₁₀ helix	trans	-57.6	-34.8	171.6	-163.8	173.2	0	0	0	113	F88 V99 W100 Y484 A583 W587	F88-I102 HydrophobicContact CE2-CB 4.15Å; F88-I102 HydrophobicContact CE2-CD1 3.84Å; F88-I102 HydrophobicContact CE2-CG2 3.79Å; F88-I102 HydrophobicContact CZ-CB 4.49Å; F88-I102 HydrophobicContact CZ-CG2 3.68Å; V99-I102 WeakPolarHBondContact O-CG2 3.18Å; V99-I102 PolarHBondContact O-N 2.84Å; W100-I102 HydrophobicContact CE3-CG2 4.48Å; W100-I102 PolarHBondContact O-N 2.89Å; I102-Y484 HydrophobicContact CD1-CD1 3.51Å; I102-Y484 HydrophobicContact CD1-CD2 3.87Å; I102-Y484 HydrophobicContact CD1-CE1 3.76Å; I102-Y484 HydrophobicContact CD1-CE2 4.13Å; I102-Y484 HydrophobicContact CD1-CG 3.53Å; I102-Y484 HydrophobicContact CG1-CD1 3.96Å; I102-Y484 HydrophobicContact CG1-CD2 3.31Å; I102-Y484 HydrophobicContact CG1-CE1 4.17Å; I102-Y484 HydrophobicContact CG1-CE2 3.59Å; I102-Y484 HydrophobicContact CG1-CG 3.49Å; I102-Y484 VanDerWaalsContact CG1-CG 3.49Å; I102-A583 WeakPolarHBondContact O-CA 3.43Å; I102-A583 VanDerWaalsContact O-CB 3.29Å; I102-A583 WeakPolarHBondContact O-CB 3.42Å; I102-W587 HydrophobicContact CB-CD2 3.71Å; I102-W587 HydrophobicContact CB-CE3 3.86Å; I102-W587 HydrophobicContact CB-CG 4.42Å; I102-W587 HydrophobicContact CB-CH2 3.86Å; I102-W587 HydrophobicContact CB-CZ2 3.7Å; I102-W587 HydrophobicContact CB-CZ3 3.93Å; I102-W587 HydrophobicContact CD1-CH2 4.19Å; I102-W587 HydrophobicContact CD1-CZ2 3.55Å; I102-W587 HydrophobicContact CG1-CD2 4.1Å; I102-W587 HydrophobicContact CG1-CH2 4.31Å; I102-W587 HydrophobicContact CG1-CZ2 3.68Å; I102-W587 VanDerWaalsContact N-CE3 3.31Å
103	S	92.6	Very high	92.8	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	6%	0.064	C	C	.	.	S	Bend	trans	-152.3	94	174.4	-165.7	0	0	0	0	109	W100 K101 M105 F106 C479 C581	W100-S103 CarbonylContact O-C 3.09Å; W100-S103 PolarHBondContact O-N 3.07Å; W100-S103 VanDerWaalsContact O-O 3.07Å; K101-S103 PolarHBondContact O-N 3.41Å; S103-M105 PolarHBondContact O-N 3.22Å; S103-M105 VanDerWaalsContact O-N 3.09Å; S103-F106 PolarHBondContact O-N 3.48Å; S103-C479 VanDerWaalsContact CB-SG 3.56Å; S103-C581 PolarHBondContact OG-O 2.91Å
104	P	90.6	Very high	93	Very high	13 Å²	13	14.9 Å²	14.9	8%	0.084	7%	0.069	C	C	.	.	G	3₁₀ helix	trans	-56.3	-29.4	-172.5	-28.6	36.5	0	0	0	114.7	F106 K107 Y560 K564 A580 Q582 H584	P104-F106 PolarHBondContact O-N 3.34Å; P104-K107 PolarHBondContact O-N 3.38Å; P104-Y560 VanDerWaalsContact O-CE1 3.24Å; P104-Y560 WeakPolarHBondContact O-CE1 3.38Å; P104-K564 HydrophobicContact CB-CD 4.41Å; P104-K564 HydrophobicContact CB-CG 4.24Å; P104-A580 WeakPolarHBondContact CD-O 3.28Å; P104-Q582 WeakPolarHBondContact CD-O 3.19Å; P104-H584 HydrophobicContact CG-CB 4.18Å
105	M	92.4	Very high	93.2	Very high	27 Å²	27	14.9 Å²	14.9	13%	0.133	7%	0.07	C	C	.	.	G	3₁₀ helix	trans	-57.4	-36.1	174.7	-170.5	175.4	75.2	0	0	112.4	S103 G561 I565 L577 A580 C581	S103-M105 PolarHBondContact O-N 3.22Å; S103-M105 VanDerWaalsContact O-N 3.09Å; M105-G561 WeakPolarHBondContact O-CA 3.49Å; M105-I565 HydrophobicContact SD-CD1 4.01Å; M105-I565 HydrophobicContact SD-CG1 4.4Å; M105-L577 HydrophobicContact SD-CD1 3.64Å; M105-A580 HydrophobicContact CB-CB 4.14Å; M105-A580 WeakPolarHBondContact CB-O 3.4Å; M105-A580 PolarHBondContact N-O 2.95Å; M105-C581 WeakPolarHBondContact CE-SG 3.35Å
106	F	94.4	Very high	93.4	Very high	27 Å²	27	14.9 Å²	14.9	12%	0.118	7%	0.07	C	C	.	.	G	3₁₀ helix	trans	-94.5	13.7	-177.1	-66.6	-78.7	0	0	0	113.8	W100 S103 P104 G108 V109 I475 C479 I483 I557	W100-F106 HydrophobicContact CE3-CB 3.87Å; W100-F106 HydrophobicContact CZ3-CB 4.05Å; S103-F106 PolarHBondContact O-N 3.48Å; P104-F106 PolarHBondContact O-N 3.34Å; F106-G108 PolarHBondContact O-N 3.33Å; F106-G108 VanDerWaalsContact O-N 3.08Å; F106-V109 HydrophobicContact CB-CG2 4.02Å; F106-V109 HydrophobicContact CD1-CG2 4.25Å; F106-V109 VanDerWaalsContact O-CB 3.27Å; F106-V109 WeakPolarHBondContact O-CB 3.21Å; F106-V109 VanDerWaalsContact O-CG2 3.29Å; F106-V109 WeakPolarHBondContact O-CG2 3.35Å; F106-V109 PolarHBondContact O-N 2.94Å; F106-I475 HydrophobicContact CD1-CG2 3.55Å; F106-I475 HydrophobicContact CE1-CG2 3.7Å; F106-C479 HydrophobicContact CD2-CB 4.1Å; F106-C479 WeakPolarHBondContact CD2-SG 3.26Å; F106-C479 HydrophobicContact CE2-CB 4.39Å; F106-C479 HydrophobicContact CG-CB 4.23Å; F106-I483 HydrophobicContact CD2-CD1 4.34Å; F106-I483 HydrophobicContact CE2-CD1 3.2Å; F106-I483 HydrophobicContact CE2-CG1 4.47Å; F106-I483 HydrophobicContact CE2-CG2 4.37Å; F106-I483 HydrophobicContact CZ-CD1 3.34Å; F106-I557 HydrophobicContact CD1-CG2 4.3Å
107	K	94.2	Very high	93.4	Very high	25 Å²	25	14.9 Å²	14.9	11%	0.109	7%	0.07	C	C	.	.	H	α-helix	trans	-58.1	-24.4	173.6	-166.3	-179	-173.4	-177.3	0	113	W100 P104 V109 G110 Y111 E420 Y560	W100-K107 VanDerWaalsContact CB-CA 3.5Å; W100-K107 HydrophobicContact CB-CB 3.96Å; W100-K107 HydrophobicContact CB-CG 4.05Å; P104-K107 PolarHBondContact O-N 3.38Å; K107-V109 PolarHBondContact O-N 2.73Å; K107-G110 PolarHBondContact O-N 2.9Å; K107-G110 VanDerWaalsContact O-N 3.09Å; K107-Y111 HydrophobicContact CD-CE2 4.37Å; K107-Y111 HydrophobicContact CG-CE2 4.27Å; K107-Y111 WeakPolarHBondContact O-CD2 3.27Å; K107-Y111 PolarHBondContact O-N 3.08Å; K107-E420 WeakPolarHBondContact CE-OE2 3.31Å; K107-E420 IonicContact NZ-OE1 3.51Å; K107-E420 PolarHBondContact NZ-OE1 3.17Å; K107-E420 IonicContact NZ-OE2 2.69Å; K107-E420 PolarHBondContact NZ-OE2 3.01Å; K107-Y560 HydrophobicContact CB-CD1 3.75Å; K107-Y560 HydrophobicContact CB-CE1 3.45Å; K107-Y560 VanDerWaalsContact CB-CE1 3.45Å; K107-Y560 HydrophobicContact CB-CG 4.44Å; K107-Y560 HydrophobicContact CD-CE1 4.13Å; K107-Y560 HydrophobicContact CD-CE2 4.2Å; K107-Y560 WeakPolarHBondContact CD-OH 3.4Å; K107-Y560 HydrophobicContact CG-CE1 4.29Å
108	G	94.6	Very high	93.5	Very high	0 Å²	0	16.8 Å²	16.8	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-58.3	-24	170.4	0	0	0	0	0	114.5	F106 Y111 G112 C556	F106-G108 PolarHBondContact O-N 3.33Å; F106-G108 VanDerWaalsContact O-N 3.08Å; G108-Y111 PolarHBondContact O-N 3.43Å; G108-G112 PolarHBondContact O-N 3.4Å; G108-C556 WeakPolarHBondContact CA-O 3.29Å
109	V	95.6	Very high	93.7	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-64.4	-42.3	173.7	-176.6	0	0	0	0	110.3	W100 F106 K107 Y111 G112 M113 I472 I475 I557	W100-V109 HydrophobicContact CD2-CB 4.17Å; W100-V109 HydrophobicContact CE3-CB 4.39Å; W100-V109 HydrophobicContact CH2-CB 3.75Å; W100-V109 HydrophobicContact CH2-CG1 3.52Å; W100-V109 HydrophobicContact CH2-CG2 4.13Å; W100-V109 HydrophobicContact CZ2-CB 3.51Å; W100-V109 HydrophobicContact CZ2-CG1 3.21Å; W100-V109 HydrophobicContact CZ2-CG2 4.39Å; W100-V109 HydrophobicContact CZ3-CB 4.19Å; W100-V109 HydrophobicContact CZ3-CG1 4.41Å; W100-V109 HydrophobicContact CZ3-CG2 4.29Å; F106-V109 HydrophobicContact CB-CG2 4.02Å; F106-V109 HydrophobicContact CD1-CG2 4.25Å; F106-V109 VanDerWaalsContact O-CB 3.27Å; F106-V109 WeakPolarHBondContact O-CB 3.21Å; F106-V109 VanDerWaalsContact O-CG2 3.29Å; F106-V109 WeakPolarHBondContact O-CG2 3.35Å; F106-V109 PolarHBondContact O-N 2.94Å; K107-V109 PolarHBondContact O-N 2.73Å; V109-Y111 PolarHBondContact O-N 3.08Å; V109-G112 PolarHBondContact O-N 3.03Å; V109-M113 HydrophobicContact CG1-CE 4.12Å; V109-M113 WeakPolarHBondContact O-CG 3.47Å; V109-M113 PolarHBondContact O-N 3.43Å; V109-I472 HydrophobicContact CG1-CG2 3.7Å; V109-I475 HydrophobicContact CG2-CG2 3.69Å; V109-I557 HydrophobicContact CG2-CD1 3.98Å; V109-I557 HydrophobicContact CG2-CG1 3.99Å; V109-I557 HydrophobicContact CG2-CG2 4.2Å
110	G	95	Very high	93.7	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-65	-37.5	174.9	0	0	0	0	0	112.9	W100 K107 G112 M113 M114	W100-G110 VanDerWaalsContact NE1-CA 3.32Å; W100-G110 VanDerWaalsContact NE1-N 3.19Å; K107-G110 PolarHBondContact O-N 2.9Å; K107-G110 VanDerWaalsContact O-N 3.09Å; G110-G112 VanDerWaalsContact C-N 3.34Å; G110-M113 WeakPolarHBondContact O-CB 3.27Å; G110-M113 PolarHBondContact O-N 2.89Å; G110-M114 PolarHBondContact O-N 3.26Å
111	Y	94.8	Very high	93.7	Very high	66 Å²	66	19.5 Å²	19.5	26%	0.259	9%	0.094	S	C	.	.	H	α-helix	trans	-64.5	-41.1	173	-77.2	-73.2	0	0	0	111.1	L97 K107 G108 V109 M114 V115 Y560	L97-Y111 HydrophobicContact CD1-CD1 4.47Å; L97-Y111 HydrophobicContact CD1-CE1 4.13Å; L97-Y111 HydrophobicContact CD2-CD1 3.75Å; L97-Y111 HydrophobicContact CD2-CD2 3.88Å; L97-Y111 HydrophobicContact CD2-CE1 3.99Å; L97-Y111 HydrophobicContact CD2-CE2 4.13Å; L97-Y111 HydrophobicContact CD2-CG 3.69Å; L97-Y111 VanDerWaalsContact CD2-N 3.28Å; K107-Y111 HydrophobicContact CD-CE2 4.37Å; K107-Y111 HydrophobicContact CG-CE2 4.27Å; K107-Y111 WeakPolarHBondContact O-CD2 3.27Å; K107-Y111 PolarHBondContact O-N 3.08Å; G108-Y111 PolarHBondContact O-N 3.43Å; V109-Y111 PolarHBondContact O-N 3.08Å; Y111-M114 HydrophobicContact CD1-CE 4.03Å; Y111-M114 PolarHBondContact O-N 2.91Å; Y111-V115 WeakPolarHBondContact O-CG2 3.46Å; Y111-V115 PolarHBondContact O-N 3.4Å; Y111-Y560 HydrophobicContact CD2-CD2 4.21Å; Y111-Y560 AromaticContact CE2-CD2 3.85Å; Y111-Y560 HydrophobicContact CE2-CD2 3.85Å; Y111-Y560 AromaticContact CE2-CE2 3.87Å; Y111-Y560 HydrophobicContact CE2-CE2 3.87Å
112	G	94.7	Very high	93.9	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-58.8	-46.1	172.5	0	0	0	0	0	112.5	G108 V109 G110 M114 V115 V116 S553	G108-G112 PolarHBondContact O-N 3.4Å; V109-G112 PolarHBondContact O-N 3.03Å; G110-G112 VanDerWaalsContact C-N 3.34Å; G112-M114 VanDerWaalsContact C-N 3.34Å; G112-M114 PolarHBondContact O-N 3.26Å; G112-V115 PolarHBondContact O-N 3.49Å; G112-V116 WeakPolarHBondContact O-CG2 3.34Å; G112-V116 PolarHBondContact O-N 3.46Å; G112-S553 VanDerWaalsContact CA-O 3.27Å; G112-S553 WeakPolarHBondContact CA-O 3.29Å
113	M	94.6	Very high	93.9	Very high	0 Å²	0	17.1 Å²	17.1	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-56.2	-46.9	174.3	-70	175.1	169.8	0	0	111.6	C96 W100 V109 G110 V115 V116 S117 A305 I310 I472 M476	C96-M113 HydrophobicContact CB-SD 4.48Å; W100-M113 HydrophobicContact CZ2-CE 4.04Å; W100-M113 HydrophobicContact CZ2-SD 4.49Å; V109-M113 HydrophobicContact CG1-CE 4.12Å; V109-M113 WeakPolarHBondContact O-CG 3.47Å; V109-M113 PolarHBondContact O-N 3.43Å; G110-M113 WeakPolarHBondContact O-CB 3.27Å; G110-M113 PolarHBondContact O-N 2.89Å; M113-V115 PolarHBondContact O-N 2.95Å; M113-V116 PolarHBondContact O-N 3.35Å; M113-S117 PolarHBondContact O-N 3.5Å; M113-S117 PolarHBondContact O-OG 2.99Å; M113-A305 HydrophobicContact CE-CB 4.46Å; M113-A305 WeakPolarHBondContact CG-O 3.44Å; M113-I310 HydrophobicContact CE-CD1 4.24Å; M113-I310 HydrophobicContact SD-CD1 4.09Å; M113-I472 HydrophobicContact CE-CG2 3.78Å; M113-I472 HydrophobicContact CG-CG2 3.82Å; M113-M476 HydrophobicContact CE-SD 3.76Å
114	M	93.9	Very high	93.9	Very high	42 Å²	42	18.2 Å²	18.2	21%	0.207	9%	0.088	C	C	.	.	H	α-helix	trans	-62.2	-42.8	178.6	-173.3	-175.3	73.9	0	0	112.6	L97 G110 Y111 G112 S117 T118 L413 A416	L97-M114 HydrophobicContact CD1-SD 4.16Å; G110-M114 PolarHBondContact O-N 3.26Å; Y111-M114 HydrophobicContact CD1-CE 4.03Å; Y111-M114 PolarHBondContact O-N 2.91Å; G112-M114 VanDerWaalsContact C-N 3.34Å; G112-M114 PolarHBondContact O-N 3.26Å; M114-S117 PolarHBondContact O-N 2.91Å; M114-T118 PolarHBondContact O-N 3.49Å; M114-T118 PolarHBondContact O-OG1 3.2Å; M114-L413 HydrophobicContact CG-CD2 3.62Å; M114-L413 WeakPolarHBondContact O-CD2 3.25Å; M114-A416 HydrophobicContact CG-CB 4.36Å; M114-A416 HydrophobicContact SD-CB 3.97Å
115	V	94.5	Very high	94.1	Very high	31 Å²	31	17.6 Å²	17.6	19%	0.188	8%	0.084	C	C	.	.	H	α-helix	trans	-63.1	-46.1	176.6	170.7	0	0	0	0	110.6	Y111 G112 M113 T118 Y119	Y111-V115 WeakPolarHBondContact O-CG2 3.46Å; Y111-V115 PolarHBondContact O-N 3.4Å; G112-V115 PolarHBondContact O-N 3.49Å; M113-V115 PolarHBondContact O-N 2.95Å; V115-T118 WeakPolarHBondContact O-CB 3.45Å; V115-T118 PolarHBondContact O-N 3.48Å; V115-T118 VanDerWaalsContact O-N 3.15Å; V115-Y119 HydrophobicContact CG1-CD2 3.94Å; V115-Y119 HydrophobicContact CG1-CE2 3.35Å; V115-Y119 WeakPolarHBondContact O-CD2 3.34Å; V115-Y119 PolarHBondContact O-N 3.2Å
116	V	93.1	Very high	94.2	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-61.3	-47.1	176.9	174.7	0	0	0	0	111.1	G112 M113 T118 Y119 I120 A465 L469 I472	G112-V116 WeakPolarHBondContact O-CG2 3.34Å; G112-V116 PolarHBondContact O-N 3.46Å; M113-V116 PolarHBondContact O-N 3.35Å; V116-T118 PolarHBondContact O-N 3.14Å; V116-Y119 PolarHBondContact O-N 3.44Å; V116-I120 HydrophobicContact CG1-CD1 3.62Å; V116-I120 HydrophobicContact CG1-CG1 4.21Å; V116-I120 WeakPolarHBondContact O-CG1 3.38Å; V116-I120 PolarHBondContact O-N 3.39Å; V116-A465 HydrophobicContact CG1-CB 3.96Å; V116-L469 HydrophobicContact CG1-CD2 3.77Å; V116-L469 HydrophobicContact CG1-CG 4.15Å; V116-I472 HydrophobicContact CG2-CD1 4.09Å
117	S	93.4	Very high	94.2	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-59.6	-32.9	175.5	-63.5	0	0	0	0	113.1	M113 M114 G121 W306	M113-S117 PolarHBondContact O-N 3.5Å; M113-S117 PolarHBondContact O-OG 2.99Å; M114-S117 PolarHBondContact O-N 2.91Å; S117-G121 PolarHBondContact O-N 3.41Å; S117-W306 PolarHBondContact OG-O 2.87Å
118	T	94.3	Very high	94.3	Very high	45 Å²	45	14.3 Å²	14.3	28%	0.276	7%	0.069	S	C	.	.	H	α-helix	trans	-66.8	-50.1	176.6	-56	0	0	0	0	110.7	M114 V115 V116 I120 G121 I122 L413	M114-T118 PolarHBondContact O-N 3.49Å; M114-T118 PolarHBondContact O-OG1 3.2Å; V115-T118 WeakPolarHBondContact O-CB 3.45Å; V115-T118 PolarHBondContact O-N 3.48Å; V115-T118 VanDerWaalsContact O-N 3.15Å; V116-T118 PolarHBondContact O-N 3.14Å; T118-I120 PolarHBondContact O-N 3.39Å; T118-G121 PolarHBondContact O-N 3.08Å; T118-I122 HydrophobicContact CG2-CD1 4.03Å; T118-I122 WeakPolarHBondContact O-CD1 3.31Å; T118-I122 VanDerWaalsContact O-CG1 3.28Å; T118-I122 WeakPolarHBondContact O-CG1 3.4Å; T118-I122 PolarHBondContact O-N 3.28Å; T118-L413 WeakPolarHBondContact OG1-CD2 3.46Å
119	Y	94.2	Very high	94.4	Very high	56 Å²	56	14.3 Å²	14.3	22%	0.22	7%	0.069	C	C	.	.	H	α-helix	trans	-61.4	-47	178.1	-65.5	-44.6	0	0	0	112	V115 V116 G121 I122 Y123 M460 A464 M549 S552	V115-Y119 HydrophobicContact CG1-CD2 3.94Å; V115-Y119 HydrophobicContact CG1-CE2 3.35Å; V115-Y119 WeakPolarHBondContact O-CD2 3.34Å; V115-Y119 PolarHBondContact O-N 3.2Å; V116-Y119 PolarHBondContact O-N 3.44Å; Y119-G121 VanDerWaalsContact C-N 3.34Å; Y119-G121 PolarHBondContact O-N 3.02Å; Y119-I122 PolarHBondContact O-N 2.85Å; Y119-Y123 WeakPolarHBondContact O-CD1 3.41Å; Y119-Y123 PolarHBondContact O-N 3.47Å; Y119-M460 HydrophobicContact CD1-CE 3.96Å; Y119-M460 HydrophobicContact CG-CE 4.36Å; Y119-A464 HydrophobicContact CD2-CB 4.01Å; Y119-A464 HydrophobicContact CG-CB 4.09Å; Y119-M549 HydrophobicContact CD1-CE 3.76Å; Y119-M549 HydrophobicContact CD2-CE 4.26Å; Y119-M549 HydrophobicContact CE1-CE 3.96Å; Y119-M549 HydrophobicContact CE2-CE 4.42Å; Y119-M549 HydrophobicContact CG-CE 3.93Å; Y119-S552 WeakPolarHBondContact CE2-OG 3.38Å; Y119-S552 PolarHBondContact OH-OG 2.85Å
120	I	92.8	Very high	94.4	Very high	1 Å²	1	14.7 Å²	14.7	1%	0.005	7%	0.071	C	C	.	.	H	α-helix	trans	-59.6	-47.9	176.9	-59.6	171.8	0	0	0	110.1	V116 T118 I122 Y123 Y124 W306 L409 A465	V116-I120 HydrophobicContact CG1-CD1 3.62Å; V116-I120 HydrophobicContact CG1-CG1 4.21Å; V116-I120 WeakPolarHBondContact O-CG1 3.38Å; V116-I120 PolarHBondContact O-N 3.39Å; T118-I120 PolarHBondContact O-N 3.39Å; I120-I122 PolarHBondContact O-N 2.91Å; I120-I122 VanDerWaalsContact O-N 3.17Å; I120-Y123 VanDerWaalsContact CA-CE1 3.4Å; I120-Y123 HydrophobicContact CB-CE1 4.08Å; I120-Y123 HydrophobicContact CG1-CE1 3.94Å; I120-Y123 HydrophobicContact CG2-CE1 4.32Å; I120-Y123 PolarHBondContact O-N 3.49Å; I120-Y124 WeakPolarHBondContact O-CB 3.44Å; I120-Y124 PolarHBondContact O-N 2.68Å; I120-W306 HydrophobicContact CD1-CD2 3.81Å; I120-W306 HydrophobicContact CD1-CE3 3.9Å; I120-W306 HydrophobicContact CD1-CH2 3.83Å; I120-W306 HydrophobicContact CD1-CZ2 3.75Å; I120-W306 HydrophobicContact CD1-CZ3 3.91Å; I120-W306 HydrophobicContact CG2-CH2 4.22Å; I120-W306 HydrophobicContact CG2-CZ3 3.99Å; I120-L409 HydrophobicContact CB-CD1 4.24Å; I120-L409 HydrophobicContact CG2-CD1 3.62Å; I120-L409 HydrophobicContact CG2-CD2 4.48Å; I120-A465 HydrophobicContact CD1-CB 3.82Å; I120-A465 HydrophobicContact CG1-CB 4.09Å
121	G	94.4	Very high	94.4	Very high	5 Å²	5	14.8 Å²	14.8	5%	0.052	7%	0.072	C	C	.	.	H	α-helix	trans	-58.6	-30.5	179.4	0	0	0	0	0	113.8	S117 T118 Y119 N125 Q406	S117-G121 PolarHBondContact O-N 3.41Å; T118-G121 PolarHBondContact O-N 3.08Å; Y119-G121 VanDerWaalsContact C-N 3.34Å; Y119-G121 PolarHBondContact O-N 3.02Å; G121-N125 WeakPolarHBondContact O-CB 3.43Å; G121-N125 PolarHBondContact O-N 3.34Å; G121-Q406 PolarHBondContact O-NE2 3.46Å; G121-Q406 PolarHBondContact O-OE1 2.92Å
122	I	94.4	Very high	94.5	Very high	12 Å²	12	12.6 Å²	12.6	6%	0.062	6%	0.064	C	C	.	.	H	α-helix	trans	-73.3	-61.5	177.2	-66.1	158.5	0	0	0	110.7	T118 Y119 I120 Y124 N125 V126 L444 L448 M460	T118-I122 HydrophobicContact CG2-CD1 4.03Å; T118-I122 WeakPolarHBondContact O-CD1 3.31Å; T118-I122 VanDerWaalsContact O-CG1 3.28Å; T118-I122 WeakPolarHBondContact O-CG1 3.4Å; T118-I122 PolarHBondContact O-N 3.28Å; Y119-I122 PolarHBondContact O-N 2.85Å; I120-I122 PolarHBondContact O-N 2.91Å; I120-I122 VanDerWaalsContact O-N 3.17Å; I122-Y124 VanDerWaalsContact C-N 3.33Å; I122-Y124 PolarHBondContact O-N 3.46Å; I122-N125 PolarHBondContact O-N 3.33Å; I122-V126 PolarHBondContact O-N 3.05Å; I122-L444 HydrophobicContact CD1-CB 3.82Å; I122-L444 HydrophobicContact CD1-CD1 3.74Å; I122-L444 HydrophobicContact CD1-CG 4.42Å; I122-L444 HydrophobicContact CG1-CB 4.15Å; I122-L444 HydrophobicContact CG2-CB 4.45Å; I122-L448 HydrophobicContact CG2-CD1 4.39Å; I122-M460 HydrophobicContact CB-CE 4.4Å; I122-M460 HydrophobicContact CG2-CE 4.46Å
123	Y	93	Very high	94.6	Very high	9 Å²	9	13.3 Å²	13.3	4%	0.035	7%	0.067	C	C	.	.	H	α-helix	trans	-70.6	-32.4	-173.2	79	-105.4	0	0	0	112	Y119 I120 N125 V126 V127 M460 D461	Y119-Y123 WeakPolarHBondContact O-CD1 3.41Å; Y119-Y123 PolarHBondContact O-N 3.47Å; I120-Y123 VanDerWaalsContact CA-CE1 3.4Å; I120-Y123 HydrophobicContact CB-CE1 4.08Å; I120-Y123 HydrophobicContact CG1-CE1 3.94Å; I120-Y123 HydrophobicContact CG2-CE1 4.32Å; I120-Y123 PolarHBondContact O-N 3.49Å; Y123-N125 VanDerWaalsContact C-N 3.31Å; Y123-N125 PolarHBondContact O-N 2.95Å; Y123-V126 WeakPolarHBondContact O-CB 3.02Å; Y123-V126 PolarHBondContact O-N 3.44Å; Y123-V127 PolarHBondContact O-N 2.78Å; Y123-M460 HydrophobicContact CD1-CB 3.89Å; Y123-M460 HydrophobicContact CD1-CE 4.38Å; Y123-M460 HydrophobicContact CG-CB 4.27Å; Y123-D461 HydrophobicContact CD2-CB 4.29Å; Y123-D461 HydrophobicContact CE2-CB 3.82Å; Y123-D461 WeakPolarHBondContact CE2-OD1 3Å; Y123-D461 VanDerWaalsContact CZ-OD1 3.27Å; Y123-D461 PolarHBondContact OH-OD1 3.31Å
124	Y	92.9	Very high	94.6	Very high	24 Å²	24	13.4 Å²	13.4	9%	0.094	7%	0.067	C	C	.	.	H	α-helix	trans	-66.6	-34.4	177.6	-162.8	-95	0	0	0	111.3	G47 L48 I120 I122 V127 I128 G402 T405	G47-Y124 WeakPolarHBondContact CA-OH 3.44Å; L48-Y124 HydrophobicContact CB-CE2 4.39Å; L48-Y124 HydrophobicContact CD1-CE1 4.41Å; L48-Y124 HydrophobicContact CD1-CE2 4.08Å; L48-Y124 HydrophobicContact CG-CE2 4.47Å; L48-Y124 PolarHBondContact N-OH 3.41Å; L48-Y124 VanDerWaalsContact N-OH 3.11Å; I120-Y124 WeakPolarHBondContact O-CB 3.44Å; I120-Y124 PolarHBondContact O-N 2.68Å; I122-Y124 VanDerWaalsContact C-N 3.33Å; I122-Y124 PolarHBondContact O-N 3.46Å; Y124-V127 WeakPolarHBondContact O-CB 3.41Å; Y124-V127 PolarHBondContact O-N 3.32Å; Y124-I128 HydrophobicContact CD1-CD1 4.05Å; Y124-I128 HydrophobicContact CE1-CD1 4.19Å; Y124-I128 WeakPolarHBondContact O-CG1 3.37Å; Y124-I128 PolarHBondContact O-N 2.88Å; Y124-I128 VanDerWaalsContact O-N 3.17Å; Y124-G402 WeakPolarHBondContact CE1-O 3.39Å; Y124-T405 HydrophobicContact CE1-CG2 4.13Å; Y124-T405 PolarHBondContact OH-OG1 3.48Å
125	N	95.3	Very high	94.8	Very high	0 Å²	0	13.2 Å²	13.2	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-71.3	-30.9	175	-149.8	52.3	0	0	0	113	G121 I122 Y123 V127 I128 C129 S227 W228	G121-N125 WeakPolarHBondContact O-CB 3.43Å; G121-N125 PolarHBondContact O-N 3.34Å; I122-N125 PolarHBondContact O-N 3.33Å; Y123-N125 VanDerWaalsContact C-N 3.31Å; Y123-N125 PolarHBondContact O-N 2.95Å; N125-V127 VanDerWaalsContact C-N 3.27Å; N125-V127 PolarHBondContact O-N 2.95Å; N125-I128 PolarHBondContact O-N 3.07Å; N125-C129 WeakPolarHBondContact O-CB 3.46Å; N125-C129 PolarHBondContact O-N 3.14Å; N125-S227 VanDerWaalsContact CG-OG 3.28Å; N125-S227 PolarHBondContact ND2-OG 3.22Å; N125-S227 VanDerWaalsContact ND2-OG 3.15Å; N125-S227 PolarHBondContact OD1-OG 3.31Å; N125-W228 HydrophobicContact CB-CZ2 4.04Å; N125-W228 VanDerWaalsContact ND2-CD2 3.29Å; N125-W228 VanDerWaalsContact ND2-CG 3.29Å; N125-W228 PolarHBondContact ND2-NE1 3.21Å
126	V	95.1	Very high	94.8	Very high	2 Å²	2	16 Å²	16	1%	0.012	8%	0.075	C	C	.	.	H	α-helix	trans	-62.8	-39.2	172.5	176.2	0	0	0	0	110.4	I122 Y123 C129 I130 L224 L448 L457	I122-V126 PolarHBondContact O-N 3.05Å; Y123-V126 WeakPolarHBondContact O-CB 3.02Å; Y123-V126 PolarHBondContact O-N 3.44Å; V126-C129 VanDerWaalsContact O-CB 3.23Å; V126-C129 WeakPolarHBondContact O-CB 3.41Å; V126-C129 PolarHBondContact O-N 3.07Å; V126-I130 HydrophobicContact CG1-CD1 4.42Å; V126-I130 WeakPolarHBondContact O-CG1 3.48Å; V126-I130 PolarHBondContact O-N 2.96Å; V126-L224 HydrophobicContact CG2-CD1 4.15Å; V126-L448 HydrophobicContact CB-CB 4.48Å; V126-L448 HydrophobicContact CG1-CB 4.17Å; V126-L448 HydrophobicContact CG2-CB 3.77Å; V126-L448 HydrophobicContact CG2-CD2 4Å; V126-L448 HydrophobicContact CG2-CG 4.5Å; V126-L457 HydrophobicContact CB-CD1 4.32Å; V126-L457 HydrophobicContact CG1-CD1 3.93Å
127	V	94.3	Very high	94.9	Very high	7 Å²	7	18.3 Å²	18.3	4%	0.042	9%	0.086	C	C	.	.	H	α-helix	trans	-61.3	-44.7	173.2	172.4	0	0	0	0	112.1	L48 W52 Y123 Y124 N125 C129 I130 A131 F374 L457	L48-V127 HydrophobicContact CD1-CB 4.31Å; L48-V127 HydrophobicContact CD1-CG1 3.33Å; W52-V127 HydrophobicContact CH2-CG1 3.24Å; W52-V127 HydrophobicContact CZ2-CG1 4Å; W52-V127 HydrophobicContact CZ3-CG1 4.08Å; Y123-V127 PolarHBondContact O-N 2.78Å; Y124-V127 WeakPolarHBondContact O-CB 3.41Å; Y124-V127 PolarHBondContact O-N 3.32Å; N125-V127 VanDerWaalsContact C-N 3.27Å; N125-V127 PolarHBondContact O-N 2.95Å; V127-C129 VanDerWaalsContact C-N 3.27Å; V127-C129 PolarHBondContact O-N 3.26Å; V127-I130 PolarHBondContact O-N 2.91Å; V127-A131 PolarHBondContact O-N 2.79Å; V127-F374 HydrophobicContact CG1-CE2 4.35Å; V127-F374 HydrophobicContact CG1-CZ 4.3Å; V127-L457 HydrophobicContact CG2-CD1 3.88Å; V127-L457 HydrophobicContact CG2-CD2 4.37Å
128	I	95.8	Very high	95	Very high	1 Å²	1	18.3 Å²	18.3	1%	0.005	9%	0.086	C	C	.	.	H	α-helix	trans	-61.1	-40	175.7	-62.3	170.1	0	0	0	110.5	Y124 N125 I130 A131 F132 G402 L403 Q406	Y124-I128 HydrophobicContact CD1-CD1 4.05Å; Y124-I128 HydrophobicContact CE1-CD1 4.19Å; Y124-I128 WeakPolarHBondContact O-CG1 3.37Å; Y124-I128 PolarHBondContact O-N 2.88Å; Y124-I128 VanDerWaalsContact O-N 3.17Å; N125-I128 PolarHBondContact O-N 3.07Å; I128-I130 PolarHBondContact O-N 2.81Å; I128-A131 WeakPolarHBondContact O-CB 3.32Å; I128-A131 PolarHBondContact O-N 3.25Å; I128-A131 VanDerWaalsContact O-N 3.15Å; I128-F132 HydrophobicContact CG2-CD2 3.85Å; I128-F132 HydrophobicContact CG2-CE2 3.68Å; I128-F132 WeakPolarHBondContact O-CD2 3.4Å; I128-F132 PolarHBondContact O-N 3.49Å; I128-G402 WeakPolarHBondContact CD1-O 3.43Å; I128-L403 HydrophobicContact CG2-CD2 4.45Å; I128-Q406 HydrophobicContact CD1-CB 3.87Å; I128-Q406 HydrophobicContact CD1-CG 4.25Å
129	C	95.7	Very high	95	Very high	0 Å²	0	21.3 Å²	21.3	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-58	-44.4	174	154.8	0	0	0	0	112.3	N125 V126 V127 A131 F132 Y133 I220 C223 L224	N125-C129 WeakPolarHBondContact O-CB 3.46Å; N125-C129 PolarHBondContact O-N 3.14Å; V126-C129 VanDerWaalsContact O-CB 3.23Å; V126-C129 WeakPolarHBondContact O-CB 3.41Å; V126-C129 PolarHBondContact O-N 3.07Å; V127-C129 VanDerWaalsContact C-N 3.27Å; V127-C129 PolarHBondContact O-N 3.26Å; C129-A131 VanDerWaalsContact C-N 3.29Å; C129-A131 PolarHBondContact O-N 3.42Å; C129-F132 WeakPolarHBondContact O-CB 3.37Å; C129-F132 PolarHBondContact O-N 3.15Å; C129-Y133 PolarHBondContact O-N 3.25Å; C129-I220 VanDerWaalsContact SG-CG2 3.53Å; C129-I220 PolarHBondContact SG-O 3.05Å; C129-C223 HydrophobicContact CB-CB 4.45Å; C129-C223 WeakPolarHBondContact O-CB 3.19Å; C129-C223 VanDerWaalsContact SG-CB 3.58Å; C129-L224 HydrophobicContact CB-CB 4.19Å; C129-L224 HydrophobicContact CB-CD1 4.14Å; C129-L224 PolarHBondContact SG-N 3.06Å
130	I	95.4	Very high	94.9	Very high	8 Å²	8	21.3 Å²	21.3	4%	0.041	10%	0.104	C	C	.	.	H	α-helix	trans	-62.7	-39.5	175.3	-63.8	167.1	0	0	0	110.2	V126 V127 I128 F132 Y133 Y134 W199 F374	V126-I130 HydrophobicContact CG1-CD1 4.42Å; V126-I130 WeakPolarHBondContact O-CG1 3.48Å; V126-I130 PolarHBondContact O-N 2.96Å; V127-I130 PolarHBondContact O-N 2.91Å; I128-I130 PolarHBondContact O-N 2.81Å; I130-F132 PolarHBondContact O-N 3.08Å; I130-Y133 WeakPolarHBondContact O-CB 3.11Å; I130-Y133 PolarHBondContact O-N 3.45Å; I130-Y134 HydrophobicContact CG2-CD2 3.98Å; I130-Y134 HydrophobicContact CG2-CE2 4.05Å; I130-Y134 WeakPolarHBondContact O-CD2 3.2Å; I130-Y134 PolarHBondContact O-N 2.85Å; I130-W199 HydrophobicContact CD1-CH2 4.02Å; I130-W199 HydrophobicContact CG2-CH2 3.92Å; I130-W199 HydrophobicContact CG2-CZ3 3.55Å; I130-F374 HydrophobicContact CB-CE1 4.2Å; I130-F374 HydrophobicContact CB-CE2 4.49Å; I130-F374 HydrophobicContact CB-CZ 4.04Å; I130-F374 HydrophobicContact CG2-CD1 3.66Å; I130-F374 HydrophobicContact CG2-CD2 4.15Å; I130-F374 HydrophobicContact CG2-CE1 3.52Å; I130-F374 HydrophobicContact CG2-CE2 4.02Å; I130-F374 HydrophobicContact CG2-CG 3.99Å; I130-F374 HydrophobicContact CG2-CZ 3.71Å
131	A	95.7	Very high	94.6	Very high	2 Å²	2	29.3 Å²	29.3	2%	0.017	15%	0.147	C	C	.	.	H	α-helix	trans	-63.4	-39.2	173.8	0	0	0	0	0	112.8	V127 I128 C129 Y134 F135 F374 L398 I399	V127-A131 PolarHBondContact O-N 2.79Å; I128-A131 WeakPolarHBondContact O-CB 3.32Å; I128-A131 PolarHBondContact O-N 3.25Å; I128-A131 VanDerWaalsContact O-N 3.15Å; C129-A131 VanDerWaalsContact C-N 3.29Å; C129-A131 PolarHBondContact O-N 3.42Å; A131-Y134 PolarHBondContact O-N 3.49Å; A131-F135 VanDerWaalsContact O-CB 3.3Å; A131-F135 WeakPolarHBondContact O-CB 3.35Å; A131-F135 PolarHBondContact O-N 3.29Å; A131-F374 HydrophobicContact CB-CE1 4.29Å; A131-L398 HydrophobicContact CB-CB 4.16Å; A131-I399 HydrophobicContact CB-CG1 3.79Å
132	F	97.1	Very high	94.2	Very high	19 Å²	19	33.9 Å²	33.9	8%	0.083	17%	0.17	C	C	.	.	H	α-helix	trans	-60.7	-44.1	170.8	-86.6	-67.5	0	0	0	112.4	I128 C129 I130 Y134 F135 F136 C223 V226 V230 I399	I128-F132 HydrophobicContact CG2-CD2 3.85Å; I128-F132 HydrophobicContact CG2-CE2 3.68Å; I128-F132 WeakPolarHBondContact O-CD2 3.4Å; I128-F132 PolarHBondContact O-N 3.49Å; C129-F132 WeakPolarHBondContact O-CB 3.37Å; C129-F132 PolarHBondContact O-N 3.15Å; I130-F132 PolarHBondContact O-N 3.08Å; F132-Y134 PolarHBondContact O-N 3.17Å; F132-F135 WeakPolarHBondContact O-CB 3.42Å; F132-F135 PolarHBondContact O-N 3.07Å; F132-F136 HydrophobicContact CB-CE2 4.25Å; F132-F136 HydrophobicContact CD1-CE2 4.23Å; F132-F136 HydrophobicContact CD1-CZ 4.3Å; F132-F136 WeakPolarHBondContact O-CD2 3.34Å; F132-F136 WeakPolarHBondContact O-CG 3.19Å; F132-F136 PolarHBondContact O-N 3.43Å; F132-C223 HydrophobicContact CB-CB 4.21Å; F132-V226 HydrophobicContact CD1-CG1 4.35Å; F132-V226 HydrophobicContact CE1-CG1 4.33Å; F132-V230 HydrophobicContact CZ-CG2 4.24Å; F132-I399 HydrophobicContact CB-CD1 4.49Å; F132-I399 HydrophobicContact CD1-CD1 3.59Å; F132-I399 HydrophobicContact CD1-CG1 4.26Å; F132-I399 HydrophobicContact CD2-CD1 4.48Å; F132-I399 HydrophobicContact CD2-CG1 4.29Å; F132-I399 HydrophobicContact CD2-CG2 4.47Å; F132-I399 HydrophobicContact CE1-CD1 3.84Å; F132-I399 HydrophobicContact CE1-CG1 4.38Å; F132-I399 HydrophobicContact CE1-CG2 3.9Å; F132-I399 HydrophobicContact CE2-CG1 4.41Å; F132-I399 HydrophobicContact CE2-CG2 3.78Å; F132-I399 HydrophobicContact CG-CD1 3.94Å; F132-I399 HydrophobicContact CG-CG1 4.21Å; F132-I399 HydrophobicContact CZ-CD1 4.4Å; F132-I399 HydrophobicContact CZ-CG1 4.45Å; F132-I399 HydrophobicContact CZ-CG2 3.44Å; F132-I399 VanDerWaalsContact CZ-CG2 3.44Å
133	Y	96.4	Very high	94.1	Very high	16 Å²	16	33.4 Å²	33.4	6%	0.063	17%	0.167	C	C	.	.	H	α-helix	trans	-57.3	-52.2	177.3	174.7	-92.4	0	0	0	110.9	C129 I130 F135 F136 M137 Y198 Y202 V203 P219	C129-Y133 PolarHBondContact O-N 3.25Å; I130-Y133 WeakPolarHBondContact O-CB 3.11Å; I130-Y133 PolarHBondContact O-N 3.45Å; Y133-F135 VanDerWaalsContact C-N 3.34Å; Y133-F135 PolarHBondContact O-N 2.89Å; Y133-F136 PolarHBondContact O-N 2.98Å; Y133-M137 HydrophobicContact CD1-CG 4.22Å; Y133-M137 HydrophobicContact CE1-CG 3.78Å; Y133-M137 HydrophobicContact CE2-CG 4.16Å; Y133-M137 HydrophobicContact CE2-SD 4.46Å; Y133-M137 VanDerWaalsContact O-CG 3.3Å; Y133-M137 WeakPolarHBondContact O-CG 3.45Å; Y133-M137 PolarHBondContact O-N 3.15Å; Y133-Y198 HydrophobicContact CE1-CE1 4.43Å; Y133-Y198 PolarHBondContact OH-OH 3.34Å; Y133-Y202 WeakPolarHBondContact OH-CE1 3.27Å; Y133-V203 HydrophobicContact CD1-CG1 4.21Å; Y133-V203 HydrophobicContact CD1-CG2 4.4Å; Y133-V203 HydrophobicContact CE1-CB 4.38Å; Y133-V203 HydrophobicContact CE1-CG1 4.05Å; Y133-V203 HydrophobicContact CE1-CG2 3.63Å; Y133-P219 HydrophobicContact CD2-CB 4.13Å; Y133-P219 HydrophobicContact CE2-CB 3.76Å
134	Y	96	Very high	93.9	Very high	1 Å²	1	33.7 Å²	33.7	0%	0.004	17%	0.17	C	C	.	.	H	α-helix	trans	-62.9	-39.8	177.3	-88.2	-92.3	0	0	0	112.5	I130 A131 F132 F136 M137 S138 W145 Y198 W199 V203 F374 P378 F395	I130-Y134 HydrophobicContact CG2-CD2 3.98Å; I130-Y134 HydrophobicContact CG2-CE2 4.05Å; I130-Y134 WeakPolarHBondContact O-CD2 3.2Å; I130-Y134 PolarHBondContact O-N 2.85Å; A131-Y134 PolarHBondContact O-N 3.49Å; F132-Y134 PolarHBondContact O-N 3.17Å; Y134-F136 VanDerWaalsContact C-N 3.33Å; Y134-F136 PolarHBondContact O-N 3Å; Y134-M137 PolarHBondContact O-N 3.35Å; Y134-S138 PolarHBondContact O-N 3.05Å; Y134-S138 PolarHBondContact O-OG 2.85Å; Y134-W145 HydrophobicContact CD1-CE3 4.12Å; Y134-W145 AromaticContact CD1-CH2 3.61Å; Y134-W145 HydrophobicContact CD1-CH2 3.61Å; Y134-W145 HydrophobicContact CD1-CZ2 4.18Å; Y134-W145 AromaticContact CD1-CZ3 3.57Å; Y134-W145 HydrophobicContact CD1-CZ3 3.57Å; Y134-W145 HydrophobicContact CE1-CD2 4.31Å; Y134-W145 AromaticContact CE1-CE3 3.91Å; Y134-W145 HydrophobicContact CE1-CE3 3.91Å; Y134-W145 HydrophobicContact CE1-CH2 4.21Å; Y134-W145 AromaticContact CE1-CZ3 3.85Å; Y134-W145 HydrophobicContact CE1-CZ3 3.85Å; Y134-Y198 HydrophobicContact CE1-CD1 4.15Å; Y134-Y198 AromaticContact CE1-CE1 3.89Å; Y134-Y198 HydrophobicContact CE1-CE1 3.89Å; Y134-Y198 AromaticContact CZ-CE1 3.99Å; Y134-W199 AromaticContact CE2-CE3 3.98Å; Y134-W199 HydrophobicContact CE2-CE3 3.98Å; Y134-W199 AromaticContact CE2-CZ3 3.95Å; Y134-W199 HydrophobicContact CE2-CZ3 3.95Å; Y134-V203 HydrophobicContact CE2-CG1 4.44Å; Y134-V203 HydrophobicContact CE2-CG2 4.26Å; Y134-F374 AromaticContact CD2-CD1 3.82Å; Y134-F374 HydrophobicContact CD2-CD1 3.82Å; Y134-F374 HydrophobicContact CD2-CE1 4.39Å; Y134-F374 HydrophobicContact CE2-CB 4.18Å; Y134-F374 AromaticContact CE2-CD1 3.9Å; Y134-F374 HydrophobicContact CE2-CD1 3.9Å; Y134-F374 HydrophobicContact CE2-CG 4.39Å; Y134-F374 HydrophobicContact CG-CD1 4.46Å; Y134-F374 PolarHBondContact OH-O 2.89Å; Y134-P378 HydrophobicContact CE1-CB 4.46Å; Y134-P378 HydrophobicContact CE1-CG 4.33Å; Y134-F395 VanDerWaalsContact CB-CE1 3.48Å; Y134-F395 HydrophobicContact CD1-CE1 4.01Å; Y134-F395 AromaticContact CD1-CE2 3.61Å; Y134-F395 HydrophobicContact CD1-CE2 3.61Å; Y134-F395 AromaticContact CD1-CZ 3.23Å; Y134-F395 HydrophobicContact CD1-CZ 3.23Å; Y134-F395 HydrophobicContact CD2-CE1 4.37Å; Y134-F395 HydrophobicContact CD2-CZ 4.37Å; Y134-F395 HydrophobicContact CE1-CZ 4.05Å; Y134-F395 HydrophobicContact CG-CD1 4.36Å; Y134-F395 AromaticContact CG-CE1 3.71Å; Y134-F395 HydrophobicContact CG-CE1 3.71Å; Y134-F395 AromaticContact CG-CE2 3.91Å; Y134-F395 HydrophobicContact CG-CE2 3.91Å; Y134-F395 AromaticContact CG-CZ 3.42Å; Y134-F395 HydrophobicContact CG-CZ 3.42Å; Y134-F395 VanDerWaalsContact CG-CZ 3.42Å
135	F	96.4	Very high	93.9	Very high	38 Å²	38	32.6 Å²	32.6	17%	0.167	17%	0.166	C	C	.	.	H	α-helix	trans	-57.1	-44.1	175.5	175	-103.6	0	0	0	112.5	A131 F132 Y133 S138 M139 L392 F395 F396 I399	A131-F135 VanDerWaalsContact O-CB 3.3Å; A131-F135 WeakPolarHBondContact O-CB 3.35Å; A131-F135 PolarHBondContact O-N 3.29Å; F132-F135 WeakPolarHBondContact O-CB 3.42Å; F132-F135 PolarHBondContact O-N 3.07Å; Y133-F135 VanDerWaalsContact C-N 3.34Å; Y133-F135 PolarHBondContact O-N 2.89Å; F135-S138 PolarHBondContact O-N 3.04Å; F135-M139 HydrophobicContact CD1-CE 3.77Å; F135-M139 HydrophobicContact CE1-CE 3.18Å; F135-M139 HydrophobicContact CE2-CE 4.33Å; F135-M139 HydrophobicContact CZ-CE 3.51Å; F135-L392 HydrophobicContact CD2-CD2 3.88Å; F135-L392 HydrophobicContact CE2-CD2 3.79Å; F135-L392 HydrophobicContact CZ-CD2 4.46Å; F135-L392 WeakPolarHBondContact O-CD2 3.49Å; F135-F395 HydrophobicContact CB-CB 4Å; F135-F396 HydrophobicContact CD2-CB 3.96Å; F135-F396 HydrophobicContact CE2-CB 3.8Å; F135-F396 HydrophobicContact CE2-CD2 4.06Å; F135-F396 HydrophobicContact CE2-CG 4.2Å; F135-F396 HydrophobicContact CZ-CD2 4.25Å; F135-I399 HydrophobicContact CB-CD1 3.77Å; F135-I399 HydrophobicContact CD1-CD1 4.37Å; F135-I399 HydrophobicContact CG-CD1 4Å
136	F	96.2	Very high	93.5	Very high	89 Å²	89	33.6 Å²	33.6	39%	0.39	17%	0.172	S	C	.	.	H	α-helix	trans	-68.8	-39.7	175.6	-65.6	-50.5	0	0	0	112.3	F132 Y133 Y134 S138 M139	F132-F136 HydrophobicContact CB-CE2 4.25Å; F132-F136 HydrophobicContact CD1-CE2 4.23Å; F132-F136 HydrophobicContact CD1-CZ 4.3Å; F132-F136 WeakPolarHBondContact O-CD2 3.34Å; F132-F136 WeakPolarHBondContact O-CG 3.19Å; F132-F136 PolarHBondContact O-N 3.43Å; Y133-F136 PolarHBondContact O-N 2.98Å; Y134-F136 VanDerWaalsContact C-N 3.33Å; Y134-F136 PolarHBondContact O-N 3Å; F136-S138 PolarHBondContact O-N 3.28Å; F136-M139 HydrophobicContact CD1-CE 4Å; F136-M139 HydrophobicContact CD1-SD 4.4Å; F136-M139 HydrophobicContact CE1-CE 4.45Å; F136-M139 WeakPolarHBondContact O-CB 3.32Å; F136-M139 PolarHBondContact O-N 3.23Å; F136-M139 VanDerWaalsContact O-N 3.15Å
137	M	94.8	Very high	93	Very high	49 Å²	49	37.5 Å²	37.5	24%	0.241	19%	0.187	C	C	.	.	H	α-helix	trans	-67.5	-23.3	177.4	-66.4	-55.5	-59.7	0	0	113.2	Y133 Y134 M139 T140 P144 W145	Y133-M137 HydrophobicContact CD1-CG 4.22Å; Y133-M137 HydrophobicContact CE1-CG 3.78Å; Y133-M137 HydrophobicContact CE2-CG 4.16Å; Y133-M137 HydrophobicContact CE2-SD 4.46Å; Y133-M137 VanDerWaalsContact O-CG 3.3Å; Y133-M137 WeakPolarHBondContact O-CG 3.45Å; Y133-M137 PolarHBondContact O-N 3.15Å; Y134-M137 PolarHBondContact O-N 3.35Å; M137-M139 VanDerWaalsContact C-N 3.26Å; M137-M139 PolarHBondContact O-N 3.15Å; M137-T140 PolarHBondContact O-OG1 3.11Å; M137-T140 VanDerWaalsContact O-OG1 3.12Å; M137-P144 HydrophobicContact CE-CG 3.78Å; M137-W145 HydrophobicContact CB-CZ3 4.05Å
138	S	95.4	Very high	92.5	Very high	0 Å²	0	39 Å²	39	0%	0	20%	0.197	C	C	.	.	T	Hydrogen-bonded Turn	trans	-75.9	-7.7	173.9	-56.8	0	0	0	0	114	Y134 F135 F136 T140 W145 S391	Y134-S138 PolarHBondContact O-N 3.05Å; Y134-S138 PolarHBondContact O-OG 2.85Å; F135-S138 PolarHBondContact O-N 3.04Å; F136-S138 PolarHBondContact O-N 3.28Å; S138-T140 PolarHBondContact O-N 3.3Å; S138-W145 WeakPolarHBondContact OG-CH2 3.44Å; S138-S391 PolarHBondContact OG-OG 2.85Å
139	M	94.1	Very high	92.1	Very high	109 Å²	109	45.9 Å²	45.9	54%	0.537	23%	0.234	S	C	.	.	S	Bend	trans	-80	51.3	175.6	-60.5	-175.7	-174.7	0	0	111.8	F135 F136 M137 L392	F135-M139 HydrophobicContact CD1-CE 3.77Å; F135-M139 HydrophobicContact CE1-CE 3.18Å; F135-M139 HydrophobicContact CE2-CE 4.33Å; F135-M139 HydrophobicContact CZ-CE 3.51Å; F136-M139 HydrophobicContact CD1-CE 4Å; F136-M139 HydrophobicContact CD1-SD 4.4Å; F136-M139 HydrophobicContact CE1-CE 4.45Å; F136-M139 WeakPolarHBondContact O-CB 3.32Å; F136-M139 PolarHBondContact O-N 3.23Å; F136-M139 VanDerWaalsContact O-N 3.15Å; M137-M139 VanDerWaalsContact C-N 3.26Å; M137-M139 PolarHBondContact O-N 3.15Å; M139-L392 HydrophobicContact CE-CD2 4.4Å; M139-L392 HydrophobicContact CG-CD2 3.78Å
140	T	91.9	Very high	91.7	Very high	56 Å²	56	46.9 Å²	46.9	34%	0.344	24%	0.24	S	C	.	.	S	Bend	trans	-138.7	161.2	-175.8	54.8	0	0	0	0	110.2	M137 S138 L142 P388	M137-T140 PolarHBondContact O-OG1 3.11Å; M137-T140 VanDerWaalsContact O-OG1 3.12Å; S138-T140 PolarHBondContact O-N 3.3Å; T140-L142 PolarHBondContact OG1-O 3.07Å; T140-P388 VanDerWaalsContact O-CB 3.29Å; T140-P388 WeakPolarHBondContact O-CB 3.41Å; T140-P388 WeakPolarHBondContact O-CG 3.3Å
141	N	86.3	Confident	91.4	Very high	169 Å²	169	52.7 Å²	52.7	90%	0.904	28%	0.278	S	S	*	.	S	Bend	trans	-75.1	-28.5	176.8	-69.7	-30	0	0	0	112.6
142	L	87.3	Confident	91.1	Very high	101 Å²	101	55 Å²	55	53%	0.529	29%	0.286	S	S	.	.	S	Bend	trans	-132.9	125.5	180	-177.4	66.3	0	0	0	108.4	T140 T146 Y147	T140-L142 PolarHBondContact OG1-O 3.07Å; L142-T146 HydrophobicContact CD1-CG2 4.32Å; L142-Y147 HydrophobicContact CD2-CD1 3.95Å; L142-Y147 HydrophobicContact CD2-CE1 3.46Å; L142-Y147 VanDerWaalsContact CD2-CE1 3.46Å; L142-Y147 HydrophobicContact CG-CD1 4.39Å; L142-Y147 HydrophobicContact CG-CE1 3.94Å
143	L	91.2	Very high	90.8	Very high	1 Å²	1	55.3 Å²	55.3	1%	0.005	29%	0.289	C	S	.	.			trans	-69.8	137.4	-176.6	-63.7	172.8	0	0	0	110.5	W145 T146 T382 P388	L143-W145 HydrophobicContact CB-CD2 4.31Å; L143-W145 HydrophobicContact CB-CZ2 4.16Å; L143-W145 HydrophobicContact CD1-CZ2 4Å; L143-W145 HydrophobicContact CD2-CH2 4.04Å; L143-W145 HydrophobicContact CD2-CZ2 3.72Å; L143-W145 HydrophobicContact CG-CZ2 4.17Å; L143-W145 PolarHBondContact O-N 2.86Å; L143-T146 WeakPolarHBondContact O-CB 3.45Å; L143-T146 PolarHBondContact O-N 3.45Å; L143-T146 PolarHBondContact O-OG1 3.21Å; L143-T382 HydrophobicContact CD1-CG2 4.18Å; L143-P388 HydrophobicContact CD2-CB 4.4Å; L143-P388 HydrophobicContact CD2-CG 4.39Å; L143-P388 HydrophobicContact CG-CG 4.34Å
144	P	89.8	Confident	90.3	Very high	15 Å²	15	56.8 Å²	56.8	10%	0.097	30%	0.3	C	S	.	.	T	Hydrogen-bonded Turn	trans	-59.8	-27.8	-178.2	-25.8	33.3	0	0	0	114.7	M137 N150 W152 Y198	M137-P144 HydrophobicContact CE-CG 3.78Å; P144-N150 PolarHBondContact O-ND2 2.62Å; P144-W152 HydrophobicContact CB-CZ2 4.5Å; P144-Y198 HydrophobicContact CB-CD2 4.07Å; P144-Y198 HydrophobicContact CB-CE2 3.45Å; P144-Y198 VanDerWaalsContact CB-CE2 3.45Å; P144-Y198 HydrophobicContact CG-CE2 4.36Å
145	W	91.3	Very high	89.7	Confident	2 Å²	2	63.1 Å²	63.1	1%	0.008	34%	0.341	C	S	.	.	T	Hydrogen-bonded Turn	trans	-95.1	19.9	-177.7	54.2	85.5	0	0	0	113.7	Y134 M137 S138 L143 S195 Y198 P378 S391 F395	Y134-W145 HydrophobicContact CD1-CE3 4.12Å; Y134-W145 AromaticContact CD1-CH2 3.61Å; Y134-W145 HydrophobicContact CD1-CH2 3.61Å; Y134-W145 HydrophobicContact CD1-CZ2 4.18Å; Y134-W145 AromaticContact CD1-CZ3 3.57Å; Y134-W145 HydrophobicContact CD1-CZ3 3.57Å; Y134-W145 HydrophobicContact CE1-CD2 4.31Å; Y134-W145 AromaticContact CE1-CE3 3.91Å; Y134-W145 HydrophobicContact CE1-CE3 3.91Å; Y134-W145 HydrophobicContact CE1-CH2 4.21Å; Y134-W145 AromaticContact CE1-CZ3 3.85Å; Y134-W145 HydrophobicContact CE1-CZ3 3.85Å; M137-W145 HydrophobicContact CB-CZ3 4.05Å; S138-W145 WeakPolarHBondContact OG-CH2 3.44Å; L143-W145 HydrophobicContact CB-CD2 4.31Å; L143-W145 HydrophobicContact CB-CZ2 4.16Å; L143-W145 HydrophobicContact CD1-CZ2 4Å; L143-W145 HydrophobicContact CD2-CH2 4.04Å; L143-W145 HydrophobicContact CD2-CZ2 3.72Å; L143-W145 HydrophobicContact CG-CZ2 4.17Å; L143-W145 PolarHBondContact O-N 2.86Å; W145-S195 PolarHBondContact O-OG 3.17Å; W145-Y198 HydrophobicContact CB-CD1 4.09Å; W145-Y198 HydrophobicContact CB-CG 3.95Å; W145-Y198 AromaticContact CE3-CD1 3.83Å; W145-Y198 HydrophobicContact CE3-CD1 3.83Å; W145-Y198 AromaticContact CE3-CE1 3.48Å; W145-Y198 HydrophobicContact CE3-CE1 3.48Å; W145-Y198 VanDerWaalsContact CE3-CE1 3.48Å; W145-Y198 AromaticContact CE3-CZ 3.88Å; W145-Y198 AromaticContact CZ3-CE1 3.96Å; W145-Y198 HydrophobicContact CZ3-CE1 3.96Å; W145-P378 HydrophobicContact CD2-CB 4.38Å; W145-P378 HydrophobicContact CG-CB 4.38Å; W145-P378 HydrophobicContact CZ2-CB 4.31Å; W145-P378 PolarHBondContact NE1-O 2.84Å; W145-P378 VanDerWaalsContact NE1-O 3.14Å; W145-S391 WeakPolarHBondContact CZ2-OG 3.32Å; W145-F395 HydrophobicContact CH2-CE2 4.26Å; W145-F395 HydrophobicContact CZ2-CE2 4.11Å
146	T	86.9	Confident	88.9	Confident	20 Å²	20	65.2 Å²	65.2	12%	0.123	35%	0.354	C	S	.	.	S	Bend	trans	-86.2	-29.9	178.6	-60.9	0	0	0	0	113.7	L142 L143 T382	L142-T146 HydrophobicContact CD1-CG2 4.32Å; L143-T146 WeakPolarHBondContact O-CB 3.45Å; L143-T146 PolarHBondContact O-N 3.45Å; L143-T146 PolarHBondContact O-OG1 3.21Å; T146-T382 WeakPolarHBondContact OG1-CG2 3.37Å
147	Y	84.3	Confident	88.3	Confident	84 Å²	84	61.8 Å²	61.8	33%	0.329	34%	0.341	S	S	.	.			trans	-134.3	158.1	-169.8	54.6	-85.1	0	0	0	112.4	L142 N149 N150 N153	L142-Y147 HydrophobicContact CD2-CD1 3.95Å; L142-Y147 HydrophobicContact CD2-CE1 3.46Å; L142-Y147 VanDerWaalsContact CD2-CE1 3.46Å; L142-Y147 HydrophobicContact CG-CD1 4.39Å; L142-Y147 HydrophobicContact CG-CE1 3.94Å; Y147-N149 HydrophobicContact CD2-CB 4.01Å; Y147-N150 VanDerWaalsContact CE2-CG 3.5Å; Y147-N150 WeakPolarHBondContact CE2-ND2 3.32Å; Y147-N150 WeakPolarHBondContact CE2-OD1 3.47Å; Y147-N150 PolarHBondContact O-ND2 3.36Å; Y147-N150 PolarHBondContact OH-OD1 3.25Å; Y147-N153 PolarHBondContact O-OD1 3.43Å
148	C	85	Confident	87.3	Confident	38 Å²	38	61.3 Å²	61.3	26%	0.257	34%	0.342	S	S	.	.	S	Bend	trans	-92.5	8.6	-178.3	-71	0	0	0	0	114.5	N150 N153 C157 G159	C148-N150 PolarHBondContact O-N 3.11Å; C148-N153 VanDerWaalsContact CA-OD1 3.28Å; C148-N153 WeakPolarHBondContact CA-OD1 3.49Å; C148-N153 WeakPolarHBondContact O-CB 3.44Å; C148-N153 PolarHBondContact O-OD1 2.93Å; C148-C157 VanDerWaalsContact CA-SG 3.58Å; C148-C157 HydrophobicContact CB-CB 3.6Å; C148-C157 WeakPolarHBondContact CB-SG 3.46Å; C148-C157 WeakPolarHBondContact SG-CB 3.4Å; C148-C157 PolarHBondContact SG-O 3.22Å; C148-C157 VanDerWaalsContact SG-O 3.38Å; C148-C157 CovalentContact SG-SG 2.03Å; C148-C157 PolarHBondContact SG-SG 3.32Å; C148-G159 PolarHBondContact SG-N 3.08Å
149	N	86.6	Confident	85.8	Confident	146 Å²	146	62.3 Å²	62.3	78%	0.781	35%	0.352	S	S	*	.			trans	-99	39.6	-176.5	-166.4	21.5	0	0	0	112.7	Y147	Y147-N149 HydrophobicContact CD2-CB 4.01Å
150	N	87.6	Confident	83.9	Confident	22 Å²	22	59.1 Å²	59.1	12%	0.118	34%	0.339	C	S	.	.	S	Bend	trans	-106.1	160.3	176.5	-59.7	-75.6	0	0	0	111.7	P144 Y147 C148 W152 N153	P144-N150 PolarHBondContact O-ND2 2.62Å; Y147-N150 VanDerWaalsContact CE2-CG 3.5Å; Y147-N150 WeakPolarHBondContact CE2-ND2 3.32Å; Y147-N150 WeakPolarHBondContact CE2-OD1 3.47Å; Y147-N150 PolarHBondContact O-ND2 3.36Å; Y147-N150 PolarHBondContact OH-OD1 3.25Å; C148-N150 PolarHBondContact O-N 3.11Å; N150-W152 HydrophobicContact CB-CD2 3.58Å; N150-W152 HydrophobicContact CB-CE3 3.9Å; N150-W152 HydrophobicContact CB-CG 4.24Å; N150-W152 HydrophobicContact CB-CH2 3.67Å; N150-W152 HydrophobicContact CB-CZ2 3.31Å; N150-W152 HydrophobicContact CB-CZ3 3.95Å; N150-W152 PolarHBondContact O-N 3.5Å; N150-W152 VanDerWaalsContact O-N 3.07Å; N150-W152 WeakPolarHBondContact OD1-CH2 3.36Å; N150-W152 WeakPolarHBondContact OD1-CZ2 3.28Å; N150-N153 WeakPolarHBondContact CB-OD1 3.48Å; N150-N153 PolarHBondContact N-OD1 3.31Å; N150-N153 PolarHBondContact ND2-OD1 2.87Å; N150-N153 WeakPolarHBondContact O-CB 3.38Å; N150-N153 PolarHBondContact O-N 3.48Å
151	P	89.9	Confident	81.9	Confident	130 Å²	130	61.3 Å²	61.3	84%	0.844	35%	0.352	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.6	-21.5	179.8	-25.2	34.7	0	0	0	115.4
152	W	89.3	Confident	79.7	Confident	49 Å²	49	55.8 Å²	55.8	19%	0.186	34%	0.335	C	S	.	.	T	Hydrogen-bonded Turn	trans	-93.4	-4.3	179.9	55.7	81.1	0	0	0	113.6	P144 N150 Y198 H201 Y202	P144-W152 HydrophobicContact CB-CZ2 4.5Å; N150-W152 HydrophobicContact CB-CD2 3.58Å; N150-W152 HydrophobicContact CB-CE3 3.9Å; N150-W152 HydrophobicContact CB-CG 4.24Å; N150-W152 HydrophobicContact CB-CH2 3.67Å; N150-W152 HydrophobicContact CB-CZ2 3.31Å; N150-W152 HydrophobicContact CB-CZ3 3.95Å; N150-W152 PolarHBondContact O-N 3.5Å; N150-W152 VanDerWaalsContact O-N 3.07Å; N150-W152 WeakPolarHBondContact OD1-CH2 3.36Å; N150-W152 WeakPolarHBondContact OD1-CZ2 3.28Å; W152-Y198 AromaticContact CE2-CD2 3.8Å; W152-Y198 HydrophobicContact CH2-CE2 4.47Å; W152-Y198 AromaticContact CZ2-CD2 3.67Å; W152-Y198 HydrophobicContact CZ2-CD2 3.67Å; W152-Y198 AromaticContact CZ2-CE2 3.94Å; W152-Y198 HydrophobicContact CZ2-CE2 3.94Å; W152-Y198 AromaticContact NE1-CD2 3.81Å; W152-H201 HydrophobicContact CB-CB 4.14Å; W152-H201 PolarHBondContact O-ND1 2.86Å; W152-Y202 AromaticContact CD2-CD2 3.72Å; W152-Y202 HydrophobicContact CD2-CD2 3.72Å; W152-Y202 AromaticContact CD2-CG 3.88Å; W152-Y202 HydrophobicContact CD2-CG 3.88Å; W152-Y202 AromaticContact CE3-CD2 3.27Å; W152-Y202 HydrophobicContact CE3-CD2 3.27Å; W152-Y202 AromaticContact CE3-CE2 3.69Å; W152-Y202 HydrophobicContact CE3-CE2 3.69Å; W152-Y202 AromaticContact CE3-CG 3.87Å; W152-Y202 HydrophobicContact CE3-CG 3.87Å; W152-Y202 HydrophobicContact CG-CD2 4.3Å; W152-Y202 HydrophobicContact CG-CG 4.33Å; W152-Y202 HydrophobicContact CH2-CD2 4.43Å; W152-Y202 HydrophobicContact CH2-CE2 4.44Å; W152-Y202 AromaticContact CZ3-CD2 3.68Å; W152-Y202 HydrophobicContact CZ3-CD2 3.68Å; W152-Y202 AromaticContact CZ3-CE2 3.64Å; W152-Y202 HydrophobicContact CZ3-CE2 3.64Å; W152-Y202 HydrophobicContact CZ3-CG 4.23Å
153	N	89.9	Confident	77.3	Confident	26 Å²	26	56.5 Å²	56.5	14%	0.139	35%	0.349	C	S	.	.			trans	-82	145.7	-176.8	-71.2	128.2	0	0	0	112.2	Y147 C148 N150 C157 E197	Y147-N153 PolarHBondContact O-OD1 3.43Å; C148-N153 VanDerWaalsContact CA-OD1 3.28Å; C148-N153 WeakPolarHBondContact CA-OD1 3.49Å; C148-N153 WeakPolarHBondContact O-CB 3.44Å; C148-N153 PolarHBondContact O-OD1 2.93Å; N150-N153 WeakPolarHBondContact CB-OD1 3.48Å; N150-N153 PolarHBondContact N-OD1 3.31Å; N150-N153 PolarHBondContact ND2-OD1 2.87Å; N150-N153 WeakPolarHBondContact O-CB 3.38Å; N150-N153 PolarHBondContact O-N 3.48Å; N153-C157 HydrophobicContact CB-CB 4.38Å; N153-E197 WeakPolarHBondContact CA-OE2 3.16Å; N153-E197 WeakPolarHBondContact CB-OE2 3.46Å; N153-E197 PolarHBondContact ND2-OE2 3.1Å
154	T	86.9	Confident	74.7	Confident	47 Å²	47	59.8 Å²	59.8	29%	0.288	38%	0.383	S	S	.	.			trans	-97.2	164.6	174.7	77.7	0	0	0	0	111.3	D156 C157 E197 H201	T154-D156 PolarHBondContact O-N 2.84Å; T154-D156 VanDerWaalsContact O-N 3.14Å; T154-D156 PolarHBondContact OG1-N 3.47Å; T154-C157 VanDerWaalsContact O-CB 3.26Å; T154-C157 WeakPolarHBondContact O-CB 3.13Å; T154-C157 PolarHBondContact O-N 3.41Å; T154-C157 VanDerWaalsContact O-N 3.11Å; T154-E197 WeakPolarHBondContact CB-OE1 3.39Å; T154-E197 PolarHBondContact N-OE1 3.39Å; T154-E197 PolarHBondContact N-OE2 3.34Å; T154-E197 PolarHBondContact OG1-OE1 3.46Å; T154-H201 VanDerWaalsContact CG2-CE1 3.49Å; T154-H201 WeakPolarHBondContact CG2-CE1 3.23Å
155	P	82.7	Confident	72.1	Confident	135 Å²	135	63 Å²	63	88%	0.877	41%	0.411	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.7	-18.6	174.5	-23.2	34.9	0	0	0	114.3	C157	P155-C157 VanDerWaalsContact C-N 3.3Å
156	D	80.4	Confident	69.4	Low	82 Å²	82	70.6 Å²	70.6	44%	0.439	45%	0.446	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.7	-7.5	179.7	-64	-31.7	0	0	0	112.8	T154 S158 T192	T154-D156 PolarHBondContact O-N 2.84Å; T154-D156 VanDerWaalsContact O-N 3.14Å; T154-D156 PolarHBondContact OG1-N 3.47Å; D156-S158 PolarHBondContact O-N 2.89Å; D156-T192 PolarHBondContact O-N 3.42Å
157	C	82.1	Confident	67.1	Low	16 Å²	16	77.4 Å²	77.4	11%	0.108	48%	0.481	C	S	.	.	B	Isolated β-bridge	trans	-65.4	121	176.7	-169.9	0	0	0	0	110.7	C148 N153 T154 P155 E197	C148-C157 VanDerWaalsContact CA-SG 3.58Å; C148-C157 HydrophobicContact CB-CB 3.6Å; C148-C157 WeakPolarHBondContact CB-SG 3.46Å; C148-C157 WeakPolarHBondContact SG-CB 3.4Å; C148-C157 PolarHBondContact SG-O 3.22Å; C148-C157 VanDerWaalsContact SG-O 3.38Å; C148-C157 CovalentContact SG-SG 2.03Å; C148-C157 PolarHBondContact SG-SG 3.32Å; N153-C157 HydrophobicContact CB-CB 4.38Å; T154-C157 VanDerWaalsContact O-CB 3.26Å; T154-C157 WeakPolarHBondContact O-CB 3.13Å; T154-C157 PolarHBondContact O-N 3.41Å; T154-C157 VanDerWaalsContact O-N 3.11Å; P155-C157 VanDerWaalsContact C-N 3.3Å; C157-E197 VanDerWaalsContact CB-OE2 3.26Å; C157-E197 WeakPolarHBondContact CB-OE2 3.34Å; C157-E197 PolarHBondContact SG-OE2 3.43Å
158	S	75.3	Confident	64.9	Low	39 Å²	39	80.2 Å²	80.2	27%	0.273	50%	0.502	S	S	.	.			trans	-120.9	115	170.7	70	0	0	0	0	110	D156 R191 T192	D156-S158 PolarHBondContact O-N 2.89Å; S158-R191 WeakPolarHBondContact OG-CB 3.27Å; S158-T192 PolarHBondContact N-O 2.92Å
159	G	62.3	Low	62.5	Low	21 Å²	21	80.7 Å²	80.7	22%	0.216	51%	0.514	C	S	.	.			trans	-78.9	155.4	177.3	0	0	0	0	0	112.9	C148 V161 P194	C148-G159 PolarHBondContact SG-N 3.08Å; G159-V161 PolarHBondContact O-N 3.46Å; G159-P194 VanDerWaalsContact CA-CG 3.46Å
160	V	55.3	Low	60.5	Low	43 Å²	43	78.7 Å²	78.7	26%	0.261	51%	0.511	S	S	.	.	S	Bend	trans	-64.7	-26.8	167.5	-166.2	0	0	0	0	111.1	L358 E379 L383	V160-L358 HydrophobicContact CB-CD2 4.11Å; V160-L358 HydrophobicContact CG1-CD2 3.55Å; V160-L358 HydrophobicContact CG1-CG 4.41Å; V160-L358 HydrophobicContact CG2-CD2 3.83Å; V160-E379 HydrophobicContact CG2-CG 4.23Å; V160-L383 HydrophobicContact CB-CD2 3.63Å; V160-L383 HydrophobicContact CG1-CD1 4.14Å; V160-L383 HydrophobicContact CG1-CD2 3.28Å; V160-L383 HydrophobicContact CG1-CG 4.33Å; V160-L383 HydrophobicContact CG2-CD2 4.1Å
161	V	49.8	Very low	58.6	Low	101 Å²	101	85.6 Å²	85.6	61%	0.612	55%	0.547	S	S	*	.	S	Bend	trans	-114.6	80.2	178.2	-171.5	0	0	0	0	108.6	G159	G159-V161 PolarHBondContact O-N 3.46Å
162	G	40.9	Very low	56.3	Low	54 Å²	54	84.9 Å²	84.9	56%	0.557	54%	0.54	S	S	*	.			trans	154	68.6	169.5	0	0	0	0	0	118.4
163	S	35.6	Very low	54.2	Low	115 Å²	115	88.7 Å²	88.7	80%	0.804	56%	0.564	S	S	*	*			trans	-138.2	32.8	139.8	-66.7	0	0	0	0	110.5	A165	S163-A165 VanDerWaalsContact C-N 3.27Å
164	G	36.3	Very low	52.2	Low	70 Å²	70	91.2 Å²	91.2	72%	0.722	59%	0.588	S	S	*	*			trans	-97	49.5	159.4	0	0	0	0	0	109.3	Q166	G164-Q166 VanDerWaalsContact C-N 3.29Å; G164-Q166 PolarHBondContact O-N 2.57Å
165	A	35.8	Very low	50.5	Low	84 Å²	84	94.2 Å²	94.2	69%	0.694	61%	0.607	S	S	*	*			trans	-57.1	111.4	150.3	0	0	0	0	0	104.2	S163 L167	S163-A165 VanDerWaalsContact C-N 3.27Å; A165-L167 VanDerWaalsContact C-N 3.29Å; A165-L167 PolarHBondContact O-N 3.21Å
166	Q	34.4	Very low	48.8	Very low	160 Å²	160	91.5 Å²	91.5	75%	0.748	59%	0.588	S	S	*	*			trans	-49.4	107.5	161.9	-71.3	-168.3	-21.3	0	0	106	G164 N168	G164-Q166 VanDerWaalsContact C-N 3.29Å; G164-Q166 PolarHBondContact O-N 2.57Å; Q166-N168 PolarHBondContact O-N 2.83Å
167	L	39.1	Very low	47.1	Very low	163 Å²	163	91.2 Å²	91.2	85%	0.853	59%	0.592	S	S	*	*			trans	-65.4	69.4	161.7	-86.4	154.7	0	0	0	106.8	A165 G169	A165-L167 VanDerWaalsContact C-N 3.29Å; A165-L167 PolarHBondContact O-N 3.21Å; L167-G169 PolarHBondContact O-N 2.59Å; L167-G169 VanDerWaalsContact O-N 3.1Å
168	N	37.1	Very low	45.4	Very low	143 Å²	143	96.6 Å²	96.6	77%	0.765	62%	0.619	S	S	*	*			trans	-76.5	84.5	158	-82.8	-14.7	0	0	0	105.8	Q166	Q166-N168 PolarHBondContact O-N 2.83Å
169	G	35.2	Very low	44	Very low	49 Å²	49	99.3 Å²	99.3	51%	0.505	63%	0.634	S	S	.	*			trans	-174.8	82.9	-174.8	0	0	0	0	0	112	L167	L167-G169 PolarHBondContact O-N 2.59Å; L167-G169 VanDerWaalsContact O-N 3.1Å
170	S	44.7	Very low	43.2	Very low	103 Å²	103	100.7 Å²	100.7	72%	0.72	64%	0.643	S	S	*	*			trans	-6.1	125.5	155	-166	0	0	0	0	116.7
171	L	48.3	Very low	42.6	Very low	167 Å²	167	99.9 Å²	99.9	87%	0.874	64%	0.644	S	S	*	*			trans	41.9	78.6	148.9	-64.4	163.3	0	0	0	116.2
172	V	42	Very low	42.3	Very low	115 Å²	115	99.9 Å²	99.9	70%	0.697	64%	0.644	S	S	*	*			trans	-98	120.6	164.6	-177.7	0	0	0	0	109.4
173	N	44.1	Very low	42.4	Very low	130 Å²	130	101.2 Å²	101.2	70%	0.695	64%	0.641	S	S	*	*			trans	-47.7	134.1	-178	-90.2	-21.2	0	0	0	113.6	T175 T176	N173-T175 PolarHBondContact O-N 3.25Å; N173-T176 PolarHBondContact O-N 2.95Å; N173-T176 VanDerWaalsContact O-N 3.11Å; N173-T176 PolarHBondContact O-OG1 3.28Å
174	A	48	Very low	42.8	Very low	78 Å²	78	100.7 Å²	100.7	65%	0.645	63%	0.626	S	S	*	*	T	Hydrogen-bonded Turn	trans	-63.6	1.3	-174.8	0	0	0	0	0	116.1	S177	A174-S177 PolarHBondContact O-OG 2.98Å
175	T	50.8	Low	43.1	Very low	111 Å²	111	102 Å²	102	68%	0.681	62%	0.62	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.4	-22.8	173.9	45.2	0	0	0	0	112.7	N173	N173-T175 PolarHBondContact O-N 3.25Å
176	T	46.8	Very low	43.4	Very low	78 Å²	78	102.6 Å²	102.6	48%	0.479	62%	0.615	S	S	.	*	H	α-helix	trans	-82.4	-21.7	177.2	-4.4	0	0	0	0	113	N173 A180	N173-T176 PolarHBondContact O-N 2.95Å; N173-T176 VanDerWaalsContact O-N 3.11Å; N173-T176 PolarHBondContact O-OG1 3.28Å; T176-A180 WeakPolarHBondContact O-CB 3.44Å; T176-A180 PolarHBondContact O-N 2.98Å
177	S	46.6	Very low	43.7	Very low	76 Å²	76	100.1 Å²	100.1	53%	0.531	61%	0.607	S	S	.	*	H	α-helix	trans	-72.8	-27.8	179	59.9	0	0	0	0	113.4	A174 G181	A174-S177 PolarHBondContact O-OG 2.98Å; S177-G181 PolarHBondContact O-N 3.49Å
178	L	45.5	Very low	43.9	Very low	128 Å²	128	100.7 Å²	100.7	67%	0.67	60%	0.597	S	S	*	*	H	α-helix	trans	-77.2	-37.5	176.4	-75.3	162.3	0	0	0	111.8	V182	L178-V182 VanDerWaalsContact O-CG2 3.29Å; L178-V182 WeakPolarHBondContact O-CG2 3.46Å; L178-V182 PolarHBondContact O-N 3.49Å; L178-V182 VanDerWaalsContact O-N 3.08Å
179	V	46.8	Very low	44.5	Very low	97 Å²	97	99.8 Å²	99.8	59%	0.588	60%	0.597	S	S	*	*	H	α-helix	trans	-71.6	-41.8	173.7	-178.6	0	0	0	0	110.2	G181 V182 T183	V179-G181 PolarHBondContact O-N 2.98Å; V179-V182 PolarHBondContact O-N 3.36Å; V179-T183 PolarHBondContact O-N 3.18Å; V179-T183 PolarHBondContact O-OG1 3.38Å
180	A	43.5	Very low	45.3	Very low	49 Å²	49	105.1 Å²	105.1	41%	0.405	61%	0.607	S	S	.	*	H	α-helix	trans	-59.1	-45.5	172.3	0	0	0	0	0	111.6	T176 V182 T183 E184	T176-A180 WeakPolarHBondContact O-CB 3.44Å; T176-A180 PolarHBondContact O-N 2.98Å; A180-V182 VanDerWaalsContact C-N 3.34Å; A180-V182 PolarHBondContact O-N 3Å; A180-T183 WeakPolarHBondContact CA-OG1 3.36Å; A180-T183 PolarHBondContact O-N 3.39Å; A180-T183 PolarHBondContact O-OG1 3.12Å; A180-E184 WeakPolarHBondContact O-CB 3.36Å; A180-E184 PolarHBondContact O-N 2.94Å
181	G	43	Very low	46.4	Very low	27 Å²	27	106.5 Å²	106.5	28%	0.278	60%	0.596	S	S	.	*	H	α-helix	trans	-63.7	-33.5	177.8	0	0	0	0	0	113.8	S177 V179 V185	S177-G181 PolarHBondContact O-N 3.49Å; V179-G181 PolarHBondContact O-N 2.98Å; G181-V185 WeakPolarHBondContact O-CB 3.37Å; G181-V185 WeakPolarHBondContact O-CG2 3.49Å; G181-V185 PolarHBondContact O-N 3.08Å
182	V	43.6	Very low	47.8	Very low	101 Å²	101	100.1 Å²	100.1	61%	0.612	56%	0.564	S	S	*	*	H	α-helix	trans	-76.4	-38.6	174.9	175.9	0	0	0	0	111.4	L178 V179 A180 E184 V185 V186	L178-V182 VanDerWaalsContact O-CG2 3.29Å; L178-V182 WeakPolarHBondContact O-CG2 3.46Å; L178-V182 PolarHBondContact O-N 3.49Å; L178-V182 VanDerWaalsContact O-N 3.08Å; V179-V182 PolarHBondContact O-N 3.36Å; A180-V182 VanDerWaalsContact C-N 3.34Å; A180-V182 PolarHBondContact O-N 3Å; V182-E184 VanDerWaalsContact C-N 3.34Å; V182-V185 PolarHBondContact O-N 3.47Å; V182-V186 VanDerWaalsContact O-CG2 3.28Å; V182-V186 WeakPolarHBondContact O-CG2 3.3Å; V182-V186 PolarHBondContact O-N 2.98Å; V182-V186 VanDerWaalsContact O-N 3.09Å
183	T	43.3	Very low	49.8	Very low	82 Å²	82	95.4 Å²	95.4	50%	0.503	54%	0.536	S	S	.	.	H	α-helix	trans	-68.3	-31	171.1	40.1	0	0	0	0	113.1	V179 A180 V186 N187	V179-T183 PolarHBondContact O-N 3.18Å; V179-T183 PolarHBondContact O-OG1 3.38Å; A180-T183 WeakPolarHBondContact CA-OG1 3.36Å; A180-T183 PolarHBondContact O-N 3.39Å; A180-T183 PolarHBondContact O-OG1 3.12Å; T183-V186 PolarHBondContact O-N 3.04Å; T183-N187 WeakPolarHBondContact O-CB 3.35Å; T183-N187 PolarHBondContact O-N 3.46Å
184	E	43.4	Very low	51.9	Low	103 Å²	103	89.4 Å²	89.4	48%	0.481	50%	0.504	S	S	.	.	H	α-helix	trans	-74.4	-32.7	177.5	-157.5	-179.1	-168.8	0	0	111.6	A180 V182 R188	A180-E184 WeakPolarHBondContact O-CB 3.36Å; A180-E184 PolarHBondContact O-N 2.94Å; V182-E184 VanDerWaalsContact C-N 3.34Å; E184-R188 WeakPolarHBondContact O-CG 3.46Å; E184-R188 PolarHBondContact O-N 3.41Å
185	V	43.9	Very low	53.8	Low	97 Å²	97	85.7 Å²	85.7	59%	0.588	47%	0.474	S	S	*	.	H	α-helix	trans	-72.3	-31.9	172	171.9	0	0	0	0	111.8	G181 V182	G181-V185 WeakPolarHBondContact O-CB 3.37Å; G181-V185 WeakPolarHBondContact O-CG2 3.49Å; G181-V185 PolarHBondContact O-N 3.08Å; V182-V185 PolarHBondContact O-N 3.47Å
186	V	41.3	Very low	55.6	Low	98 Å²	98	83 Å²	83	59%	0.594	45%	0.453	S	S	*	.	H	α-helix	trans	-78	-33.5	175.9	175.6	0	0	0	0	112.2	V182 T183 R188 T189	V182-V186 VanDerWaalsContact O-CG2 3.28Å; V182-V186 WeakPolarHBondContact O-CG2 3.3Å; V182-V186 PolarHBondContact O-N 2.98Å; V182-V186 VanDerWaalsContact O-N 3.09Å; T183-V186 PolarHBondContact O-N 3.04Å; V186-R188 VanDerWaalsContact C-N 3.33Å; V186-R188 PolarHBondContact O-N 2.78Å; V186-T189 PolarHBondContact O-OG1 3.46Å
187	N	41	Very low	57.7	Low	108 Å²	108	79.5 Å²	79.5	58%	0.578	43%	0.432	S	S	*	.	G	3₁₀ helix	trans	-80	-2.1	176.3	-94	0.4	0	0	0	115.4	T183 T189	T183-N187 WeakPolarHBondContact O-CB 3.35Å; T183-N187 PolarHBondContact O-N 3.46Å; N187-T189 PolarHBondContact O-N 3.35Å
188	R	43.5	Very low	59.9	Low	174 Å²	174	75.9 Å²	75.9	66%	0.657	41%	0.406	S	S	*	.	G	3₁₀ helix	trans	-69.7	-6.1	177.1	-93.7	-179.2	-175.2	-176.7	2	114.6	E184 V186	E184-R188 WeakPolarHBondContact O-CG 3.46Å; E184-R188 PolarHBondContact O-N 3.41Å; V186-R188 VanDerWaalsContact C-N 3.33Å; V186-R188 PolarHBondContact O-N 2.78Å
189	T	48.8	Very low	62.1	Low	124 Å²	124	69.9 Å²	69.9	76%	0.761	38%	0.375	S	S	*	.	G	3₁₀ helix	trans	-94.7	-4	-170.5	48.8	0	0	0	0	115.1	V186 N187	V186-T189 PolarHBondContact O-OG1 3.46Å; N187-T189 PolarHBondContact O-N 3.35Å
190	K	53.2	Low	64.2	Low	162 Å²	162	67.5 Å²	67.5	70%	0.704	36%	0.356	S	S	*	.			trans	-141.7	25.4	-177.5	-89.8	-169.2	176.7	-173.6	0	115.9	T192	K190-T192 PolarHBondContact O-N 3.49Å
191	R	66.6	Low	66.4	Low	131 Å²	131	68.4 Å²	68.4	49%	0.494	35%	0.352	S	S	.	.	P	Polyproline II helix	trans	-72.3	122.1	175.7	-78.2	-175.3	179.1	-172.8	2.4	110.8	S158	S158-R191 WeakPolarHBondContact OG-CB 3.27Å
192	T	78.1	Confident	68.7	Low	34 Å²	34	70.9 Å²	70.9	21%	0.209	35%	0.354	C	S	.	.	B	Isolated β-bridge	trans	-102.4	149.7	176.5	48.7	0	0	0	0	110.5	D156 S158 K190 E197	D156-T192 PolarHBondContact O-N 3.42Å; S158-T192 PolarHBondContact N-O 2.92Å; K190-T192 PolarHBondContact O-N 3.49Å; T192-E197 PolarHBondContact OG1-OE1 3.4Å; T192-E197 VanDerWaalsContact OG1-OE1 3.05Å
193	S	84.4	Confident	71	Confident	16 Å²	16	66.2 Å²	66.2	11%	0.112	33%	0.325	C	S	.	.	P	Polyproline II helix	trans	-82.5	153.9	178.7	87.9	0	0	0	0	112.1	S195 E196 E197 E379	S193-S195 PolarHBondContact O-N 3.23Å; S193-E196 WeakPolarHBondContact O-CB 3.35Å; S193-E196 PolarHBondContact O-N 3.35Å; S193-E196 VanDerWaalsContact O-N 3.07Å; S193-E196 PolarHBondContact OG-N 3.21Å; S193-E197 PolarHBondContact O-N 3.15Å; S193-E379 VanDerWaalsContact CB-CD 3.46Å; S193-E379 WeakPolarHBondContact CB-OE1 3.43Å; S193-E379 WeakPolarHBondContact CB-OE2 2.94Å; S193-E379 PolarHBondContact OG-OE2 3.01Å
194	P	87.5	Confident	73.2	Confident	3 Å²	3	62.7 Å²	62.7	2%	0.019	30%	0.304	C	S	.	.	H	α-helix	trans	-59.8	-33.4	178.1	-14.6	23.1	0	0	0	112.6	G159 Y198	G159-P194 VanDerWaalsContact CA-CG 3.46Å; P194-Y198 VanDerWaalsContact O-CB 3.25Å; P194-Y198 WeakPolarHBondContact O-CB 3.37Å; P194-Y198 PolarHBondContact O-N 3.37Å
195	S	88.8	Confident	75.4	Confident	1 Å²	1	60.8 Å²	60.8	1%	0.007	30%	0.297	C	S	.	.	H	α-helix	trans	-70.3	-36	176.4	-59.6	0	0	0	0	112.4	W145 S193 W199 V375 E379	W145-S195 PolarHBondContact O-OG 3.17Å; S193-S195 PolarHBondContact O-N 3.23Å; S195-W199 WeakPolarHBondContact O-CB 3.46Å; S195-W199 PolarHBondContact O-N 3.46Å; S195-V375 WeakPolarHBondContact CB-O 3.27Å; S195-E379 WeakPolarHBondContact OG-CA 3.41Å; S195-E379 VanDerWaalsContact OG-CB 3.24Å; S195-E379 WeakPolarHBondContact OG-CB 3.32Å; S195-E379 PolarHBondContact OG-N 3.33Å
196	E	88.3	Confident	77.6	Confident	53 Å²	53	58.2 Å²	58.2	25%	0.248	28%	0.279	C	S	.	.	H	α-helix	trans	-67.5	-44.1	176.6	-169.1	-176.1	165.2	0	0	111.1	S193 W199 K200 V375	S193-E196 WeakPolarHBondContact O-CB 3.35Å; S193-E196 PolarHBondContact O-N 3.35Å; S193-E196 VanDerWaalsContact O-N 3.07Å; S193-E196 PolarHBondContact OG-N 3.21Å; E196-W199 WeakPolarHBondContact O-CB 3.42Å; E196-W199 PolarHBondContact O-N 3.36Å; E196-K200 HydrophobicContact CG-CD 4.15Å; E196-K200 WeakPolarHBondContact O-CB 3.31Å; E196-K200 WeakPolarHBondContact O-CG 3.45Å; E196-K200 PolarHBondContact O-N 2.72Å; E196-K200 WeakPolarHBondContact OE1-CE 3.3Å; E196-K200 IonicContact OE1-NZ 3.44Å; E196-K200 PolarHBondContact OE1-NZ 3.49Å; E196-V375 HydrophobicContact CB-CG1 3.76Å; E196-V375 HydrophobicContact CG-CG1 4.31Å
197	E	90.3	Very high	79.9	Confident	5 Å²	5	54 Å²	54	2%	0.023	25%	0.254	C	S	.	.	H	α-helix	trans	-68.4	-38.3	175.6	-67.5	-160.9	160.1	0	0	112.5	N153 T154 C157 T192 S193 W199 K200 H201	N153-E197 WeakPolarHBondContact CA-OE2 3.16Å; N153-E197 WeakPolarHBondContact CB-OE2 3.46Å; N153-E197 PolarHBondContact ND2-OE2 3.1Å; T154-E197 WeakPolarHBondContact CB-OE1 3.39Å; T154-E197 PolarHBondContact N-OE1 3.39Å; T154-E197 PolarHBondContact N-OE2 3.34Å; T154-E197 PolarHBondContact OG1-OE1 3.46Å; C157-E197 VanDerWaalsContact CB-OE2 3.26Å; C157-E197 WeakPolarHBondContact CB-OE2 3.34Å; C157-E197 PolarHBondContact SG-OE2 3.43Å; T192-E197 PolarHBondContact OG1-OE1 3.4Å; T192-E197 VanDerWaalsContact OG1-OE1 3.05Å; S193-E197 PolarHBondContact O-N 3.15Å; E197-W199 VanDerWaalsContact C-N 3.28Å; E197-W199 PolarHBondContact O-N 2.96Å; E197-K200 PolarHBondContact O-N 2.85Å; E197-H201 WeakPolarHBondContact O-CB 3.46Å; E197-H201 PolarHBondContact O-N 3.31Å
198	Y	92.7	Very high	82.2	Confident	0 Å²	0	55.7 Å²	55.7	0%	0	26%	0.263	C	S	.	.	I	π-helix	trans	-57.3	-45.5	172.1	-177.1	-100.9	0	0	0	110.7	Y133 Y134 P144 W145 W152 P194 Y202 V203	Y133-Y198 HydrophobicContact CE1-CE1 4.43Å; Y133-Y198 PolarHBondContact OH-OH 3.34Å; Y134-Y198 HydrophobicContact CE1-CD1 4.15Å; Y134-Y198 AromaticContact CE1-CE1 3.89Å; Y134-Y198 HydrophobicContact CE1-CE1 3.89Å; Y134-Y198 AromaticContact CZ-CE1 3.99Å; P144-Y198 HydrophobicContact CB-CD2 4.07Å; P144-Y198 HydrophobicContact CB-CE2 3.45Å; P144-Y198 VanDerWaalsContact CB-CE2 3.45Å; P144-Y198 HydrophobicContact CG-CE2 4.36Å; W145-Y198 HydrophobicContact CB-CD1 4.09Å; W145-Y198 HydrophobicContact CB-CG 3.95Å; W145-Y198 AromaticContact CE3-CD1 3.83Å; W145-Y198 HydrophobicContact CE3-CD1 3.83Å; W145-Y198 AromaticContact CE3-CE1 3.48Å; W145-Y198 HydrophobicContact CE3-CE1 3.48Å; W145-Y198 VanDerWaalsContact CE3-CE1 3.48Å; W145-Y198 AromaticContact CE3-CZ 3.88Å; W145-Y198 AromaticContact CZ3-CE1 3.96Å; W145-Y198 HydrophobicContact CZ3-CE1 3.96Å; W152-Y198 AromaticContact CE2-CD2 3.8Å; W152-Y198 HydrophobicContact CH2-CE2 4.47Å; W152-Y198 AromaticContact CZ2-CD2 3.67Å; W152-Y198 HydrophobicContact CZ2-CD2 3.67Å; W152-Y198 AromaticContact CZ2-CE2 3.94Å; W152-Y198 HydrophobicContact CZ2-CE2 3.94Å; W152-Y198 AromaticContact NE1-CD2 3.81Å; P194-Y198 VanDerWaalsContact O-CB 3.25Å; P194-Y198 WeakPolarHBondContact O-CB 3.37Å; P194-Y198 PolarHBondContact O-N 3.37Å; Y198-Y202 AromaticContact CD2-CD1 3.84Å; Y198-Y202 HydrophobicContact CD2-CD1 3.84Å; Y198-Y202 HydrophobicContact CD2-CG 4.26Å; Y198-Y202 AromaticContact CE2-CD1 3.22Å; Y198-Y202 HydrophobicContact CE2-CD1 3.22Å; Y198-Y202 AromaticContact CE2-CE1 3.71Å; Y198-Y202 HydrophobicContact CE2-CE1 3.71Å; Y198-Y202 HydrophobicContact CE2-CG 4.05Å; Y198-Y202 AromaticContact CZ-CD1 3.67Å; Y198-Y202 WeakPolarHBondContact O-CA 3.45Å; Y198-Y202 WeakPolarHBondContact O-CB 3.11Å; Y198-Y202 PolarHBondContact O-N 3.41Å; Y198-Y202 VanDerWaalsContact O-N 3.17Å; Y198-V203 HydrophobicContact CD1-CG2 3.62Å; Y198-V203 HydrophobicContact CE1-CG2 3.31Å; Y198-V203 HydrophobicContact CG-CG2 4.43Å; Y198-V203 WeakPolarHBondContact O-CG2 3.42Å; Y198-V203 PolarHBondContact O-N 2.96Å
199	W	92.3	Very high	84.3	Confident	2 Å²	2	50 Å²	50	1%	0.008	25%	0.246	C	C	.	.	I	π-helix	trans	-63	-52.7	176.3	175.1	-106	0	0	0	112.9	I130 Y134 S195 E196 E197 V203 L204 P370 F374 V375 I454 Y533	I130-W199 HydrophobicContact CD1-CH2 4.02Å; I130-W199 HydrophobicContact CG2-CH2 3.92Å; I130-W199 HydrophobicContact CG2-CZ3 3.55Å; Y134-W199 AromaticContact CE2-CE3 3.98Å; Y134-W199 HydrophobicContact CE2-CE3 3.98Å; Y134-W199 AromaticContact CE2-CZ3 3.95Å; Y134-W199 HydrophobicContact CE2-CZ3 3.95Å; S195-W199 WeakPolarHBondContact O-CB 3.46Å; S195-W199 PolarHBondContact O-N 3.46Å; E196-W199 WeakPolarHBondContact O-CB 3.42Å; E196-W199 PolarHBondContact O-N 3.36Å; E197-W199 VanDerWaalsContact C-N 3.28Å; E197-W199 PolarHBondContact O-N 2.96Å; W199-V203 HydrophobicContact CE3-CB 4.35Å; W199-V203 HydrophobicContact CE3-CG1 4.19Å; W199-V203 HydrophobicContact CZ3-CG1 4.27Å; W199-L204 HydrophobicContact CD2-CD1 4.04Å; W199-L204 HydrophobicContact CD2-CG 4.25Å; W199-L204 VanDerWaalsContact CE2-CD1 3.42Å; W199-L204 HydrophobicContact CG-CD1 4.4Å; W199-L204 HydrophobicContact CH2-CD2 4.4Å; W199-L204 HydrophobicContact CZ2-CD1 3.72Å; W199-L204 HydrophobicContact CZ2-CD2 4.32Å; W199-L204 HydrophobicContact CZ2-CG 4.24Å; W199-L204 VanDerWaalsContact NE1-CD1 3.34Å; W199-L204 WeakPolarHBondContact O-CB 3.29Å; W199-L204 WeakPolarHBondContact O-CG 3.42Å; W199-L204 PolarHBondContact O-N 3.02Å; W199-P370 HydrophobicContact CZ2-CB 4.46Å; W199-F374 HydrophobicContact CD2-CB 4.32Å; W199-F374 HydrophobicContact CE3-CB 3.7Å; W199-F374 HydrophobicContact CE3-CG 4.46Å; W199-F374 HydrophobicContact CH2-CB 3.94Å; W199-F374 AromaticContact CH2-CD2 3.82Å; W199-F374 HydrophobicContact CH2-CD2 3.82Å; W199-F374 HydrophobicContact CH2-CG 4.01Å; W199-F374 HydrophobicContact CZ3-CB 3.48Å; W199-F374 VanDerWaalsContact CZ3-CB 3.48Å; W199-F374 HydrophobicContact CZ3-CD1 4.44Å; W199-F374 HydrophobicContact CZ3-CD2 4.06Å; W199-F374 AromaticContact CZ3-CG 3.76Å; W199-F374 HydrophobicContact CZ3-CG 3.76Å; W199-V375 HydrophobicContact CB-CG2 3.71Å; W199-V375 HydrophobicContact CD2-CG2 4.41Å; W199-V375 HydrophobicContact CG-CG2 3.73Å; W199-I454 HydrophobicContact CZ2-CD1 4Å; W199-Y533 PolarHBondContact NE1-OH 3.06Å
200	K	90.5	Very high	86.3	Confident	47 Å²	47	44.1 Å²	44.1	20%	0.204	21%	0.21	C	C	.	.	I	π-helix	trans	-71.3	-49.6	-173.7	-73.3	179.8	174.1	174	0	112.9	E196 E197 N205 I206	E196-K200 HydrophobicContact CG-CD 4.15Å; E196-K200 WeakPolarHBondContact O-CB 3.31Å; E196-K200 WeakPolarHBondContact O-CG 3.45Å; E196-K200 PolarHBondContact O-N 2.72Å; E196-K200 WeakPolarHBondContact OE1-CE 3.3Å; E196-K200 IonicContact OE1-NZ 3.44Å; E196-K200 PolarHBondContact OE1-NZ 3.49Å; E197-K200 PolarHBondContact O-N 2.85Å; K200-N205 CarbonylContact O-C 3.41Å; K200-N205 VanDerWaalsContact O-CA 3.24Å; K200-N205 WeakPolarHBondContact O-CA 3.42Å; K200-N205 PolarHBondContact O-N 3Å; K200-I206 PolarHBondContact O-N 3.03Å
201	H	90.6	Very high	88	Confident	69 Å²	69	38.2 Å²	38.2	32%	0.319	20%	0.195	S	C	.	.	I	π-helix	trans	-94.8	-32.4	-169.8	-58.3	164.3	0	0	0	113	W152 T154 E197 N205	W152-H201 HydrophobicContact CB-CB 4.14Å; W152-H201 PolarHBondContact O-ND1 2.86Å; T154-H201 VanDerWaalsContact CG2-CE1 3.49Å; T154-H201 WeakPolarHBondContact CG2-CE1 3.23Å; E197-H201 WeakPolarHBondContact O-CB 3.46Å; E197-H201 PolarHBondContact O-N 3.31Å; H201-N205 WeakPolarHBondContact O-CA 3.33Å; H201-N205 WeakPolarHBondContact O-CB 3.29Å; H201-N205 PolarHBondContact O-OD1 3.19Å
202	Y	91	Very high	89.2	Confident	79 Å²	79	36 Å²	36	31%	0.31	19%	0.193	S	C	.	.	I	π-helix	trans	-99.2	-55.2	-176.8	-172.3	-104.2	0	0	0	113.4	Y133 W152 Y198 R217	Y133-Y202 WeakPolarHBondContact OH-CE1 3.27Å; W152-Y202 AromaticContact CD2-CD2 3.72Å; W152-Y202 HydrophobicContact CD2-CD2 3.72Å; W152-Y202 AromaticContact CD2-CG 3.88Å; W152-Y202 HydrophobicContact CD2-CG 3.88Å; W152-Y202 AromaticContact CE3-CD2 3.27Å; W152-Y202 HydrophobicContact CE3-CD2 3.27Å; W152-Y202 AromaticContact CE3-CE2 3.69Å; W152-Y202 HydrophobicContact CE3-CE2 3.69Å; W152-Y202 AromaticContact CE3-CG 3.87Å; W152-Y202 HydrophobicContact CE3-CG 3.87Å; W152-Y202 HydrophobicContact CG-CD2 4.3Å; W152-Y202 HydrophobicContact CG-CG 4.33Å; W152-Y202 HydrophobicContact CH2-CD2 4.43Å; W152-Y202 HydrophobicContact CH2-CE2 4.44Å; W152-Y202 AromaticContact CZ3-CD2 3.68Å; W152-Y202 HydrophobicContact CZ3-CD2 3.68Å; W152-Y202 AromaticContact CZ3-CE2 3.64Å; W152-Y202 HydrophobicContact CZ3-CE2 3.64Å; W152-Y202 HydrophobicContact CZ3-CG 4.23Å; Y198-Y202 AromaticContact CD2-CD1 3.84Å; Y198-Y202 HydrophobicContact CD2-CD1 3.84Å; Y198-Y202 HydrophobicContact CD2-CG 4.26Å; Y198-Y202 AromaticContact CE2-CD1 3.22Å; Y198-Y202 HydrophobicContact CE2-CD1 3.22Å; Y198-Y202 AromaticContact CE2-CE1 3.71Å; Y198-Y202 HydrophobicContact CE2-CE1 3.71Å; Y198-Y202 HydrophobicContact CE2-CG 4.05Å; Y198-Y202 AromaticContact CZ-CD1 3.67Å; Y198-Y202 WeakPolarHBondContact O-CA 3.45Å; Y198-Y202 WeakPolarHBondContact O-CB 3.11Å; Y198-Y202 PolarHBondContact O-N 3.41Å; Y198-Y202 VanDerWaalsContact O-N 3.17Å; Y202-R217 PolarHBondContact O-NH2 3.13Å
203	V	91.4	Very high	89.7	Confident	2 Å²	2	38.3 Å²	38.3	1%	0.012	20%	0.2	C	C	.	.	I	π-helix	trans	-67	-62.4	-177.5	179.9	0	0	0	0	109.9	Y133 Y134 Y198 W199 R217 I220	Y133-V203 HydrophobicContact CD1-CG1 4.21Å; Y133-V203 HydrophobicContact CD1-CG2 4.4Å; Y133-V203 HydrophobicContact CE1-CB 4.38Å; Y133-V203 HydrophobicContact CE1-CG1 4.05Å; Y133-V203 HydrophobicContact CE1-CG2 3.63Å; Y134-V203 HydrophobicContact CE2-CG1 4.44Å; Y134-V203 HydrophobicContact CE2-CG2 4.26Å; Y198-V203 HydrophobicContact CD1-CG2 3.62Å; Y198-V203 HydrophobicContact CE1-CG2 3.31Å; Y198-V203 HydrophobicContact CG-CG2 4.43Å; Y198-V203 WeakPolarHBondContact O-CG2 3.42Å; Y198-V203 PolarHBondContact O-N 2.96Å; W199-V203 HydrophobicContact CE3-CB 4.35Å; W199-V203 HydrophobicContact CE3-CG1 4.19Å; W199-V203 HydrophobicContact CZ3-CG1 4.27Å; V203-R217 PolarHBondContact O-NE 2.93Å; V203-I220 HydrophobicContact CG1-CD1 4Å; V203-I220 WeakPolarHBondContact O-CD1 3.32Å
204	L	89.4	Confident	89.9	Confident	9 Å²	9	39.4 Å²	39.4	5%	0.047	21%	0.214	C	C	.	.	I	π-helix	trans	-79	-40	-177.9	-62	-179.9	0	0	0	112.1	W199 I206 I454	W199-L204 HydrophobicContact CD2-CD1 4.04Å; W199-L204 HydrophobicContact CD2-CG 4.25Å; W199-L204 VanDerWaalsContact CE2-CD1 3.42Å; W199-L204 HydrophobicContact CG-CD1 4.4Å; W199-L204 HydrophobicContact CH2-CD2 4.4Å; W199-L204 HydrophobicContact CZ2-CD1 3.72Å; W199-L204 HydrophobicContact CZ2-CD2 4.32Å; W199-L204 HydrophobicContact CZ2-CG 4.24Å; W199-L204 VanDerWaalsContact NE1-CD1 3.34Å; W199-L204 WeakPolarHBondContact O-CB 3.29Å; W199-L204 WeakPolarHBondContact O-CG 3.42Å; W199-L204 PolarHBondContact O-N 3.02Å; L204-I206 VanDerWaalsContact C-N 3.31Å; L204-I206 HydrophobicContact CB-CB 4.4Å; L204-I454 HydrophobicContact CD1-CB 3.85Å; L204-I454 HydrophobicContact CD1-CG1 4.12Å; L204-I454 HydrophobicContact CD1-CG2 3.91Å; L204-I454 HydrophobicContact CD2-CB 4.43Å
205	N	90.5	Very high	90.2	Very high	63 Å²	63	45.8 Å²	45.8	34%	0.337	24%	0.243	S	C	.	.			trans	46.7	59.1	-162.5	-168.5	36.4	0	0	0	110.3	K200 H201 Q451	K200-N205 CarbonylContact O-C 3.41Å; K200-N205 VanDerWaalsContact O-CA 3.24Å; K200-N205 WeakPolarHBondContact O-CA 3.42Å; K200-N205 PolarHBondContact O-N 3Å; H201-N205 WeakPolarHBondContact O-CA 3.33Å; H201-N205 WeakPolarHBondContact O-CB 3.29Å; H201-N205 PolarHBondContact O-OD1 3.19Å; N205-Q451 HydrophobicContact CB-CG 4.42Å; N205-Q451 PolarHBondContact ND2-NE2 2.71Å; N205-Q451 VanDerWaalsContact O-CB 3.23Å; N205-Q451 WeakPolarHBondContact O-CB 3.31Å; N205-Q451 WeakPolarHBondContact O-CG 3.44Å
206	I	88.8	Confident	90.4	Very high	42 Å²	42	48.4 Å²	48.4	22%	0.215	26%	0.259	C	S	.	.			trans	-57.5	136.4	-164.1	-163.8	170.8	0	0	0	111.9	K200 L204 I454 Y455 Y533	K200-I206 PolarHBondContact O-N 3.03Å; L204-I206 VanDerWaalsContact C-N 3.31Å; L204-I206 HydrophobicContact CB-CB 4.4Å; I206-I454 HydrophobicContact CD1-CG2 3.59Å; I206-I454 HydrophobicContact CG1-CG2 4.02Å; I206-Y455 HydrophobicContact CD1-CE1 4.35Å; I206-Y455 HydrophobicContact CD1-CE2 3.91Å; I206-Y455 WeakPolarHBondContact CD1-OH 3.47Å; I206-Y455 HydrophobicContact CG1-CE2 3.76Å; I206-Y533 HydrophobicContact CD1-CD1 4.34Å; I206-Y533 HydrophobicContact CD1-CE1 3.73Å
207	S	91.2	Very high	90.7	Very high	9 Å²	9	48.4 Å²	48.4	6%	0.063	26%	0.257	C	S	.	.			trans	-77.7	163.4	174.2	62.4	0	0	0	0	111.6	D209 N212 Q451 A452 Y455	S207-D209 VanDerWaalsContact C-N 3.3Å; S207-D209 PolarHBondContact O-N 2.87Å; S207-D209 PolarHBondContact OG-O 3.42Å; S207-D209 VanDerWaalsContact OG-O 3.07Å; S207-N212 WeakPolarHBondContact CB-O 3.42Å; S207-N212 PolarHBondContact OG-O 3.04Å; S207-Q451 PolarHBondContact N-O 3.41Å; S207-A452 WeakPolarHBondContact OG-CA 3.43Å; S207-A452 WeakPolarHBondContact OG-CB 3.24Å; S207-A452 PolarHBondContact OG-N 2.86Å; S207-Y455 WeakPolarHBondContact O-CE2 3.31Å; S207-Y455 PolarHBondContact O-OH 3.28Å
208	D	87.8	Confident	90.8	Very high	145 Å²	145	54.4 Å²	54.4	78%	0.775	29%	0.288	S	S	*	.	S	Bend	trans	-68.6	-28.3	179.5	-58.3	-45.6	0	0	0	113.5
209	D	88.9	Confident	90.9	Very high	55 Å²	55	57.9 Å²	57.9	29%	0.294	31%	0.311	S	S	.	.	S	Bend	trans	-146.4	151	-172.4	-175.5	59.2	0	0	0	112	S207 G211 N212 Y536	S207-D209 VanDerWaalsContact C-N 3.3Å; S207-D209 PolarHBondContact O-N 2.87Å; S207-D209 PolarHBondContact OG-O 3.42Å; S207-D209 VanDerWaalsContact OG-O 3.07Å; D209-G211 PolarHBondContact O-N 3.35Å; D209-G211 WeakPolarHBondContact OD2-CA 3.31Å; D209-G211 PolarHBondContact OD2-N 2.99Å; D209-N212 PolarHBondContact O-N 3.32Å; D209-Y536 PolarHBondContact OD1-OH 3.23Å
210	I	90.6	Very high	91	Very high	0 Å²	0	58.1 Å²	58.1	0%	0	31%	0.312	C	S	.	.	T	Hydrogen-bonded Turn	trans	-60.8	-28.3	176.6	-171.4	173.3	0	0	0	113	N212 Y455 W456 L459 Y536 Y538 P539 W541	I210-N212 VanDerWaalsContact C-N 3.34Å; I210-Y455 HydrophobicContact CB-CD2 4.49Å; I210-Y455 HydrophobicContact CB-CG 4.31Å; I210-W456 HydrophobicContact CD1-CD2 4.08Å; I210-W456 HydrophobicContact CD1-CE3 4.43Å; I210-W456 HydrophobicContact CD1-CG 4.43Å; I210-W456 HydrophobicContact CD1-CZ2 4.36Å; I210-W456 HydrophobicContact CG1-CD2 4.11Å; I210-W456 HydrophobicContact CG1-CG 4.28Å; I210-W456 HydrophobicContact CG1-CZ2 4.08Å; I210-W456 PolarHBondContact O-NE1 2.93Å; I210-W456 VanDerWaalsContact O-NE1 3.14Å; I210-L459 HydrophobicContact CD1-CD2 4.04Å; I210-Y536 VanDerWaalsContact CG2-OH 3.27Å; I210-Y536 WeakPolarHBondContact CG2-OH 3.33Å; I210-Y536 PolarHBondContact N-OH 3.19Å; I210-Y536 VanDerWaalsContact N-OH 3.17Å; I210-Y538 HydrophobicContact CD1-CD1 4.12Å; I210-Y538 HydrophobicContact CD1-CE1 3.94Å; I210-P539 HydrophobicContact CG2-CG 3.76Å; I210-W541 HydrophobicContact CG2-CH2 3.74Å; I210-W541 HydrophobicContact CG2-CZ2 3.55Å
211	G	89.4	Confident	91.3	Very high	38 Å²	38	57.7 Å²	57.7	39%	0.392	31%	0.312	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.8	-22.3	176.7	0	0	0	0	0	113.7	D209 F213	D209-G211 PolarHBondContact O-N 3.35Å; D209-G211 WeakPolarHBondContact OD2-CA 3.31Å; D209-G211 PolarHBondContact OD2-N 2.99Å; G211-F213 PolarHBondContact O-N 3.24Å
212	N	91.3	Very high	91.6	Very high	84 Å²	84	56.2 Å²	56.2	45%	0.449	32%	0.315	S	S	.	.			trans	-94.3	89.1	178.3	-174.3	9.3	0	0	0	110.2	S207 D209 I210 G214 A452	S207-N212 WeakPolarHBondContact CB-O 3.42Å; S207-N212 PolarHBondContact OG-O 3.04Å; D209-N212 PolarHBondContact O-N 3.32Å; I210-N212 VanDerWaalsContact C-N 3.34Å; N212-G214 PolarHBondContact O-N 3.46Å; N212-G214 PolarHBondContact OD1-N 2.89Å; N212-A452 WeakPolarHBondContact O-CB 3.07Å
213	F	87.4	Confident	91.9	Very high	82 Å²	82	53 Å²	53	36%	0.36	30%	0.304	S	S	.	.			trans	-58.5	-29.2	178.6	-76	-90.2	0	0	0	112.9	G211 P447 T450 Q451 W456	G211-F213 PolarHBondContact O-N 3.24Å; F213-P447 HydrophobicContact CE1-CB 4.17Å; F213-T450 HydrophobicContact CB-CG2 4.42Å; F213-T450 HydrophobicContact CD1-CG2 4.12Å; F213-T450 VanDerWaalsContact O-CB 3.27Å; F213-T450 WeakPolarHBondContact O-CB 3.44Å; F213-Q451 PolarHBondContact O-N 3.24Å; F213-W456 AromaticContact CE1-CD1 3.76Å; F213-W456 AromaticContact CE1-CE2 3.9Å; F213-W456 HydrophobicContact CE1-CZ2 4.44Å; F213-W456 AromaticContact CE1-NE1 3.31Å; F213-W456 VanDerWaalsContact CE1-NE1 3.31Å; F213-W456 HydrophobicContact CE2-CZ2 4.21Å; F213-W456 AromaticContact CZ-CE2 3.52Å; F213-W456 AromaticContact CZ-CZ2 3.62Å; F213-W456 HydrophobicContact CZ-CZ2 3.62Å; F213-W456 AromaticContact CZ-NE1 3.29Å; F213-W456 VanDerWaalsContact CZ-NE1 3.29Å
214	G	90.3	Very high	92.1	Very high	39 Å²	39	52.9 Å²	52.9	40%	0.402	30%	0.304	S	S	.	.			trans	58.8	-144.1	-175.2	0	0	0	0	0	112	N212	N212-G214 PolarHBondContact O-N 3.46Å; N212-G214 PolarHBondContact OD1-N 2.89Å
215	E	92.8	Very high	92.5	Very high	138 Å²	138	54.5 Å²	54.5	65%	0.645	32%	0.318	S	S	*	.			trans	-91.8	152.7	-179.7	-63.2	-177	167.8	0	0	113.1	T450 Q451	E215-T450 WeakPolarHBondContact O-CA 3.31Å; E215-Q451 PolarHBondContact O-N 3.05Å
216	V	93.6	Very high	92.8	Very high	56 Å²	56	54.1 Å²	54.1	34%	0.339	32%	0.318	S	S	.	.	B	Isolated β-bridge	trans	-76.6	124.4	170.9	-179.7	0	0	0	0	109.5	L218 L221 T450	V216-L218 PolarHBondContact O-N 3.36Å; V216-L221 HydrophobicContact CG1-CB 4.15Å; V216-L221 HydrophobicContact CG1-CD2 3.99Å; V216-L221 HydrophobicContact CG1-CG 4.45Å; V216-T450 HydrophobicContact CG2-CG2 3.92Å
217	R	93.8	Very high	93.2	Very high	53 Å²	53	52.1 Å²	52.1	20%	0.2	31%	0.308	C	S	.	.			trans	-74.7	96.1	178	-57.9	-62.2	-69.2	163.3	-4.3	109.7	Y202 V203 P219 I220 L221 T449	Y202-R217 PolarHBondContact O-NH2 3.13Å; V203-R217 PolarHBondContact O-NE 2.93Å; R217-P219 VanDerWaalsContact C-CD 3.43Å; R217-P219 VanDerWaalsContact C-N 3.34Å; R217-I220 HydrophobicContact CB-CB 4.11Å; R217-I220 HydrophobicContact CB-CD1 3.93Å; R217-I220 HydrophobicContact CB-CG1 3.99Å; R217-I220 HydrophobicContact CG-CD1 4.28Å; R217-I220 WeakPolarHBondContact O-CB 3.42Å; R217-I220 PolarHBondContact O-N 3.43Å; R217-L221 PolarHBondContact O-N 3.18Å; R217-T449 WeakPolarHBondContact CB-O 3.37Å; R217-T449 PolarHBondContact N-O 2.69Å
218	L	93.8	Very high	93.5	Very high	131 Å²	131	52.5 Å²	52.5	69%	0.686	31%	0.308	S	S	*	.	H	α-helix	trans	-51.7	-40.3	-177	-62.8	179.4	0	0	0	114.9	V216 I220 L221 G222	V216-L218 PolarHBondContact O-N 3.36Å; L218-I220 VanDerWaalsContact C-N 3.33Å; L218-I220 PolarHBondContact O-N 3.09Å; L218-L221 HydrophobicContact CD2-CD2 4.27Å; L218-L221 PolarHBondContact O-N 3.31Å; L218-G222 PolarHBondContact O-N 2.82Å
219	P	93.7	Very high	93.9	Very high	72 Å²	72	51.4 Å²	51.4	47%	0.468	30%	0.296	S	S	.	.	H	α-helix	trans	-62.5	-39.1	176.3	-24	35.5	0	0	0	113	Y133 R217 C223	Y133-P219 HydrophobicContact CD2-CB 4.13Å; Y133-P219 HydrophobicContact CE2-CB 3.76Å; R217-P219 VanDerWaalsContact C-CD 3.43Å; R217-P219 VanDerWaalsContact C-N 3.34Å; P219-C223 PolarHBondContact O-N 2.99Å; P219-C223 VanDerWaalsContact O-N 3.13Å; P219-C223 PolarHBondContact O-SG 3.07Å
220	I	94.7	Very high	94.2	Very high	7 Å²	7	50.5 Å²	50.5	4%	0.036	29%	0.293	C	S	.	.	H	α-helix	trans	-70.5	-43.6	176.5	-58	-176.2	0	0	0	109.5	C129 V203 R217 L218 G222 C223 L224 T449	C129-I220 VanDerWaalsContact SG-CG2 3.53Å; C129-I220 PolarHBondContact SG-O 3.05Å; V203-I220 HydrophobicContact CG1-CD1 4Å; V203-I220 WeakPolarHBondContact O-CD1 3.32Å; R217-I220 HydrophobicContact CB-CB 4.11Å; R217-I220 HydrophobicContact CB-CD1 3.93Å; R217-I220 HydrophobicContact CB-CG1 3.99Å; R217-I220 HydrophobicContact CG-CD1 4.28Å; R217-I220 WeakPolarHBondContact O-CB 3.42Å; R217-I220 PolarHBondContact O-N 3.43Å; L218-I220 VanDerWaalsContact C-N 3.33Å; L218-I220 PolarHBondContact O-N 3.09Å; I220-G222 VanDerWaalsContact C-N 3.29Å; I220-G222 PolarHBondContact O-N 3.11Å; I220-C223 CarbonylContact O-C 3.11Å; I220-C223 WeakPolarHBondContact O-CB 3.12Å; I220-C223 PolarHBondContact O-N 3.36Å; I220-C223 VanDerWaalsContact O-N 3.07Å; I220-L224 PolarHBondContact O-N 3.42Å; I220-T449 HydrophobicContact CG2-CG2 3.88Å
221	L	96.1	Very high	94.5	Very high	39 Å²	39	50.5 Å²	50.5	20%	0.204	29%	0.293	C	S	.	.	H	α-helix	trans	-57.2	-41.8	175.4	-177.2	66.6	0	0	0	112.2	V216 R217 L218 L224 A225 F442 V446	V216-L221 HydrophobicContact CG1-CB 4.15Å; V216-L221 HydrophobicContact CG1-CD2 3.99Å; V216-L221 HydrophobicContact CG1-CG 4.45Å; R217-L221 PolarHBondContact O-N 3.18Å; L218-L221 HydrophobicContact CD2-CD2 4.27Å; L218-L221 PolarHBondContact O-N 3.31Å; L221-L224 WeakPolarHBondContact O-CB 3.45Å; L221-L224 PolarHBondContact O-N 3.07Å; L221-A225 PolarHBondContact O-N 3.43Å; L221-F442 HydrophobicContact CD1-CE2 4.14Å; L221-F442 HydrophobicContact CD1-CZ 3.98Å; L221-V446 HydrophobicContact CD1-CB 4.43Å; L221-V446 HydrophobicContact CD1-CG1 4.15Å; L221-V446 HydrophobicContact CD1-CG2 3.84Å
222	G	96.6	Very high	94.8	Very high	37 Å²	37	50 Å²	50	38%	0.381	28%	0.28	S	S	.	.	H	α-helix	trans	-61.3	-43.7	173.7	0	0	0	0	0	112.3	L218 I220 L224 A225 V226	L218-G222 PolarHBondContact O-N 2.82Å; I220-G222 VanDerWaalsContact C-N 3.29Å; I220-G222 PolarHBondContact O-N 3.11Å; G222-L224 VanDerWaalsContact C-N 3.3Å; G222-L224 PolarHBondContact O-N 3.45Å; G222-A225 WeakPolarHBondContact O-CB 3.21Å; G222-A225 PolarHBondContact O-N 3.36Å; G222-V226 WeakPolarHBondContact O-CG2 3.49Å; G222-V226 PolarHBondContact O-N 2.66Å
223	C	97.1	Very high	95	Very high	12 Å²	12	49.5 Å²	49.5	8%	0.081	28%	0.277	C	S	.	.	H	α-helix	trans	-65.9	-31.3	175.1	-64.9	0	0	0	0	112.6	C129 F132 P219 I220 V226 S227	C129-C223 HydrophobicContact CB-CB 4.45Å; C129-C223 WeakPolarHBondContact O-CB 3.19Å; C129-C223 VanDerWaalsContact SG-CB 3.58Å; F132-C223 HydrophobicContact CB-CB 4.21Å; P219-C223 PolarHBondContact O-N 2.99Å; P219-C223 VanDerWaalsContact O-N 3.13Å; P219-C223 PolarHBondContact O-SG 3.07Å; I220-C223 CarbonylContact O-C 3.11Å; I220-C223 WeakPolarHBondContact O-CB 3.12Å; I220-C223 PolarHBondContact O-N 3.36Å; I220-C223 VanDerWaalsContact O-N 3.07Å; C223-V226 PolarHBondContact O-N 2.88Å; C223-S227 VanDerWaalsContact O-CB 3.31Å; C223-S227 WeakPolarHBondContact O-CB 3.49Å; C223-S227 PolarHBondContact O-N 2.76Å
224	L	97	Very high	95.4	Very high	0 Å²	0	46.4 Å²	46.4	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-66.6	-41.3	173.6	-176.5	66.3	0	0	0	111.1	V126 C129 I220 L221 G222 S227 W228 F442 T449	V126-L224 HydrophobicContact CG2-CD1 4.15Å; C129-L224 HydrophobicContact CB-CB 4.19Å; C129-L224 HydrophobicContact CB-CD1 4.14Å; C129-L224 PolarHBondContact SG-N 3.06Å; I220-L224 PolarHBondContact O-N 3.42Å; L221-L224 WeakPolarHBondContact O-CB 3.45Å; L221-L224 PolarHBondContact O-N 3.07Å; G222-L224 VanDerWaalsContact C-N 3.3Å; G222-L224 PolarHBondContact O-N 3.45Å; L224-S227 PolarHBondContact O-N 3.37Å; L224-W228 PolarHBondContact O-N 3.29Å; L224-F442 HydrophobicContact CB-CE2 4.41Å; L224-F442 HydrophobicContact CD2-CD2 4.08Å; L224-F442 HydrophobicContact CD2-CE2 4.2Å; L224-F442 HydrophobicContact CG-CD2 3.95Å; L224-F442 HydrophobicContact CG-CE2 4.18Å; L224-T449 HydrophobicContact CB-CG2 4.29Å; L224-T449 HydrophobicContact CD2-CG2 3.69Å
225	A	97.2	Very high	95.5	Very high	43 Å²	43	44.6 Å²	44.6	36%	0.355	25%	0.246	S	C	.	.	H	α-helix	trans	-62.8	-45	174.1	0	0	0	0	0	111.4	L221 G222 S227 W228 F229 F442	L221-A225 PolarHBondContact O-N 3.43Å; G222-A225 WeakPolarHBondContact O-CB 3.21Å; G222-A225 PolarHBondContact O-N 3.36Å; A225-S227 VanDerWaalsContact C-N 3.35Å; A225-S227 PolarHBondContact O-N 3.04Å; A225-W228 PolarHBondContact O-N 3.43Å; A225-F229 VanDerWaalsContact O-CB 3.23Å; A225-F229 WeakPolarHBondContact O-CB 3.46Å; A225-F229 PolarHBondContact O-N 3.18Å; A225-F442 HydrophobicContact CB-CD2 4.43Å; A225-F442 HydrophobicContact CB-CE2 3.79Å; A225-F442 HydrophobicContact CB-CZ 4.38Å
226	V	97.6	Very high	95.5	Very high	55 Å²	55	41 Å²	41	33%	0.333	23%	0.231	S	C	.	.	H	α-helix	trans	-59.5	-45.8	174.8	171.4	0	0	0	0	111	F132 G222 C223 F229 V230	F132-V226 HydrophobicContact CD1-CG1 4.35Å; F132-V226 HydrophobicContact CE1-CG1 4.33Å; G222-V226 WeakPolarHBondContact O-CG2 3.49Å; G222-V226 PolarHBondContact O-N 2.66Å; C223-V226 PolarHBondContact O-N 2.88Å; V226-F229 PolarHBondContact O-N 3.46Å; V226-V230 HydrophobicContact CG1-CG2 4.4Å; V226-V230 WeakPolarHBondContact O-CG2 3.21Å; V226-V230 PolarHBondContact O-N 3.36Å
227	S	96.6	Very high	95.3	Very high	0 Å²	0	48.1 Å²	48.1	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-60.1	-51	-179.9	178.6	0	0	0	0	112	N125 C223 L224 A225 F229 V230 V231	N125-S227 VanDerWaalsContact CG-OG 3.28Å; N125-S227 PolarHBondContact ND2-OG 3.22Å; N125-S227 VanDerWaalsContact ND2-OG 3.15Å; N125-S227 PolarHBondContact OD1-OG 3.31Å; C223-S227 VanDerWaalsContact O-CB 3.31Å; C223-S227 WeakPolarHBondContact O-CB 3.49Å; C223-S227 PolarHBondContact O-N 2.76Å; L224-S227 PolarHBondContact O-N 3.37Å; A225-S227 VanDerWaalsContact C-N 3.35Å; A225-S227 PolarHBondContact O-N 3.04Å; S227-F229 VanDerWaalsContact C-N 3.32Å; S227-F229 PolarHBondContact O-N 3.5Å; S227-V230 PolarHBondContact O-N 3.47Å; S227-V231 VanDerWaalsContact O-CG2 3.29Å; S227-V231 WeakPolarHBondContact O-CG2 3.42Å; S227-V231 PolarHBondContact O-N 3.43Å
228	W	96.9	Very high	95.1	Very high	17 Å²	17	45.8 Å²	45.8	6%	0.064	24%	0.244	C	C	.	.	H	α-helix	trans	-63.8	-36.2	176.5	-83.6	110.9	0	0	0	113.1	N125 L224 A225 V231 F232 L410 A438 G441 F442	N125-W228 HydrophobicContact CB-CZ2 4.04Å; N125-W228 VanDerWaalsContact ND2-CD2 3.29Å; N125-W228 VanDerWaalsContact ND2-CG 3.29Å; N125-W228 PolarHBondContact ND2-NE1 3.21Å; L224-W228 PolarHBondContact O-N 3.29Å; A225-W228 PolarHBondContact O-N 3.43Å; W228-V231 PolarHBondContact O-N 3.17Å; W228-F232 WeakPolarHBondContact O-CB 3.32Å; W228-F232 PolarHBondContact O-N 3.03Å; W228-L410 HydrophobicContact CZ3-CD1 4.25Å; W228-L410 HydrophobicContact CZ3-CD2 4.32Å; W228-A438 HydrophobicContact CE3-CB 3.85Å; W228-A438 HydrophobicContact CZ3-CB 4.29Å; W228-G441 VanDerWaalsContact CE2-C 3.43Å; W228-G441 VanDerWaalsContact CZ2-C 3.44Å; W228-G441 PolarHBondContact NE1-O 2.83Å; W228-F442 HydrophobicContact CB-CB 4.44Å; W228-F442 AromaticContact CD1-CD2 3.98Å; W228-F442 HydrophobicContact CG-CB 4Å
229	F	96.6	Very high	94.8	Very high	121 Å²	121	39.8 Å²	39.8	53%	0.531	21%	0.213	S	C	.	.	H	α-helix	trans	-63.3	-45.8	175.6	-179.9	-109.8	0	0	0	111.9	A225 V226 S227 F232 L233	A225-F229 VanDerWaalsContact O-CB 3.23Å; A225-F229 WeakPolarHBondContact O-CB 3.46Å; A225-F229 PolarHBondContact O-N 3.18Å; V226-F229 PolarHBondContact O-N 3.46Å; S227-F229 VanDerWaalsContact C-N 3.32Å; S227-F229 PolarHBondContact O-N 3.5Å; F229-F232 PolarHBondContact O-N 3.27Å; F229-L233 HydrophobicContact CD1-CD1 3.96Å; F229-L233 HydrophobicContact CD1-CG 4.47Å; F229-L233 HydrophobicContact CE1-CD1 3.41Å; F229-L233 VanDerWaalsContact CE1-CD1 3.41Å; F229-L233 HydrophobicContact CE1-CG 4.14Å; F229-L233 HydrophobicContact CE2-CD1 4.34Å; F229-L233 HydrophobicContact CE2-CD2 4.31Å; F229-L233 HydrophobicContact CE2-CG 4.24Å; F229-L233 HydrophobicContact CZ-CD1 3.63Å; F229-L233 HydrophobicContact CZ-CD2 4.17Å; F229-L233 HydrophobicContact CZ-CG 4.02Å; F229-L233 WeakPolarHBondContact O-CG 3.41Å; F229-L233 PolarHBondContact O-N 2.88Å
230	V	96.4	Very high	94.5	Very high	36 Å²	36	41.3 Å²	41.3	22%	0.218	21%	0.212	C	C	.	.	H	α-helix	trans	-61	-46.3	175.1	171.4	0	0	0	0	110.8	F132 V226 S227 F232 L233 C234 L403	F132-V230 HydrophobicContact CZ-CG2 4.24Å; V226-V230 HydrophobicContact CG1-CG2 4.4Å; V226-V230 WeakPolarHBondContact O-CG2 3.21Å; V226-V230 PolarHBondContact O-N 3.36Å; S227-V230 PolarHBondContact O-N 3.47Å; V230-F232 VanDerWaalsContact C-N 3.32Å; V230-F232 PolarHBondContact O-N 2.72Å; V230-L233 PolarHBondContact O-N 2.7Å; V230-C234 PolarHBondContact O-N 2.85Å; V230-C234 PolarHBondContact O-SG 3.48Å; V230-L403 HydrophobicContact CG1-CD1 3.82Å; V230-L403 HydrophobicContact CG1-CD2 4.04Å
231	V	95.9	Very high	94.4	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-57.9	-44.9	177	172.4	0	0	0	0	111.3	S227 W228 C234 L235 L403 Q406 F407 L410	S227-V231 VanDerWaalsContact O-CG2 3.29Å; S227-V231 WeakPolarHBondContact O-CG2 3.42Å; S227-V231 PolarHBondContact O-N 3.43Å; W228-V231 PolarHBondContact O-N 3.17Å; V231-C234 PolarHBondContact O-N 3.22Å; V231-L235 HydrophobicContact CG1-CD1 4.3Å; V231-L235 PolarHBondContact O-N 3.07Å; V231-L403 HydrophobicContact CG2-CD2 3.58Å; V231-Q406 HydrophobicContact CG1-CG 4.1Å; V231-Q406 HydrophobicContact CG2-CB 4.41Å; V231-Q406 HydrophobicContact CG2-CG 3.69Å; V231-F407 HydrophobicContact CG1-CD1 4.46Å; V231-L410 HydrophobicContact CG1-CB 4.45Å; V231-L410 HydrophobicContact CG1-CD2 3.57Å
232	F	96.3	Very high	94.2	Very high	27 Å²	27	40.4 Å²	40.4	12%	0.118	21%	0.209	C	C	.	.	H	α-helix	trans	-61.6	-47.9	176.5	168.5	-104.6	0	0	0	112.2	W228 F229 V230 C234 L235 I236 T431 T434 L435 A438	W228-F232 WeakPolarHBondContact O-CB 3.32Å; W228-F232 PolarHBondContact O-N 3.03Å; F229-F232 PolarHBondContact O-N 3.27Å; V230-F232 VanDerWaalsContact C-N 3.32Å; V230-F232 PolarHBondContact O-N 2.72Å; F232-C234 VanDerWaalsContact C-N 3.32Å; F232-C234 PolarHBondContact O-N 2.96Å; F232-L235 CarbonylContact O-C 3.38Å; F232-L235 PolarHBondContact O-N 3.14Å; F232-L235 VanDerWaalsContact O-N 3.1Å; F232-I236 HydrophobicContact CE1-CD1 4.37Å; F232-I236 HydrophobicContact CZ-CD1 4.37Å; F232-I236 HydrophobicContact CZ-CG1 4.14Å; F232-I236 PolarHBondContact O-N 2.68Å; F232-T431 HydrophobicContact CE2-CG2 4.23Å; F232-T431 HydrophobicContact CZ-CG2 4.19Å; F232-T434 HydrophobicContact CD2-CG2 4.18Å; F232-L435 HydrophobicContact CD1-CD1 4.36Å; F232-L435 HydrophobicContact CD2-CB 4.08Å; F232-L435 HydrophobicContact CD2-CD1 4.03Å; F232-L435 HydrophobicContact CE1-CD1 4.25Å; F232-L435 HydrophobicContact CE2-CB 3.56Å; F232-L435 HydrophobicContact CE2-CD1 3.93Å; F232-L435 HydrophobicContact CE2-CG 4.29Å; F232-L435 HydrophobicContact CG-CD1 4.25Å; F232-L435 HydrophobicContact CZ-CB 4.15Å; F232-L435 HydrophobicContact CZ-CD1 4.04Å; F232-A438 HydrophobicContact CB-CB 4.4Å
233	L	95.4	Very high	93.9	Very high	75 Å²	75	38.6 Å²	38.6	39%	0.393	19%	0.191	S	C	.	.	H	α-helix	trans	-59.5	-43	179.1	-73.1	-177.2	0	0	0	111.8	F229 V230 L235 I236	F229-L233 HydrophobicContact CD1-CD1 3.96Å; F229-L233 HydrophobicContact CD1-CG 4.47Å; F229-L233 HydrophobicContact CE1-CD1 3.41Å; F229-L233 VanDerWaalsContact CE1-CD1 3.41Å; F229-L233 HydrophobicContact CE1-CG 4.14Å; F229-L233 HydrophobicContact CE2-CD1 4.34Å; F229-L233 HydrophobicContact CE2-CD2 4.31Å; F229-L233 HydrophobicContact CE2-CG 4.24Å; F229-L233 HydrophobicContact CZ-CD1 3.63Å; F229-L233 HydrophobicContact CZ-CD2 4.17Å; F229-L233 HydrophobicContact CZ-CG 4.02Å; F229-L233 WeakPolarHBondContact O-CG 3.41Å; F229-L233 PolarHBondContact O-N 2.88Å; V230-L233 PolarHBondContact O-N 2.7Å; L233-L235 PolarHBondContact O-N 2.8Å; L233-I236 VanDerWaalsContact O-CG2 3.28Å; L233-I236 WeakPolarHBondContact O-CG2 3.46Å; L233-I236 PolarHBondContact O-N 3.44Å
234	C	94.4	Very high	93.7	Very high	17 Å²	17	43.6 Å²	43.6	12%	0.115	21%	0.211	C	C	.	.	H	α-helix	trans	-64.3	-27.9	178.3	-65.6	0	0	0	0	112.7	V230 V231 F232 S241 S242 V245 F407	V230-C234 PolarHBondContact O-N 2.85Å; V230-C234 PolarHBondContact O-SG 3.48Å; V231-C234 PolarHBondContact O-N 3.22Å; F232-C234 VanDerWaalsContact C-N 3.32Å; F232-C234 PolarHBondContact O-N 2.96Å; C234-S241 CarbonylContact O-C 3.59Å; C234-S241 VanDerWaalsContact O-CB 3.23Å; C234-S241 WeakPolarHBondContact O-CB 3.37Å; C234-S241 PolarHBondContact O-OG 2.89Å; C234-S242 PolarHBondContact O-N 2.56Å; C234-V245 HydrophobicContact CB-CG1 4.38Å; C234-V245 HydrophobicContact CB-CG2 4.39Å; C234-F407 HydrophobicContact CB-CD1 4.1Å; C234-F407 HydrophobicContact CB-CE1 3.38Å; C234-F407 HydrophobicContact CB-CE2 4.1Å; C234-F407 HydrophobicContact CB-CZ 3.38Å; C234-F407 WeakPolarHBondContact SG-CZ 3.38Å
235	L	93.5	Very high	93.5	Very high	1 Å²	1	45.6 Å²	45.6	1%	0.005	22%	0.224	C	C	.	.	T	Hydrogen-bonded Turn	trans	-105.3	11.4	-179.7	-73.5	170.1	0	0	0	114.6	V231 F232 L233 R237 G238 F407 L410 E411 T434	V231-L235 HydrophobicContact CG1-CD1 4.3Å; V231-L235 PolarHBondContact O-N 3.07Å; F232-L235 CarbonylContact O-C 3.38Å; F232-L235 PolarHBondContact O-N 3.14Å; F232-L235 VanDerWaalsContact O-N 3.1Å; L233-L235 PolarHBondContact O-N 2.8Å; L235-R237 PolarHBondContact O-N 3.37Å; L235-R237 VanDerWaalsContact O-N 3.09Å; L235-G238 WeakPolarHBondContact O-CA 3.14Å; L235-G238 PolarHBondContact O-N 3.41Å; L235-F407 HydrophobicContact CD1-CB 4.38Å; L235-F407 HydrophobicContact CD1-CD1 4.47Å; L235-F407 HydrophobicContact CD2-CB 4.44Å; L235-F407 HydrophobicContact CG-CD1 4.49Å; L235-L410 HydrophobicContact CD1-CB 3.81Å; L235-L410 HydrophobicContact CD1-CD2 3.7Å; L235-L410 HydrophobicContact CD1-CG 3.98Å; L235-E411 HydrophobicContact CD2-CB 4.35Å; L235-T434 HydrophobicContact CB-CG2 4.05Å
236	I	92.8	Very high	93.3	Very high	62 Å²	62	43.7 Å²	43.7	32%	0.318	21%	0.208	S	C	.	.	T	Hydrogen-bonded Turn	trans	-58.5	-30.9	-173.8	-163.3	173.4	0	0	0	113.6	F232 L233 T431	F232-I236 HydrophobicContact CE1-CD1 4.37Å; F232-I236 HydrophobicContact CZ-CD1 4.37Å; F232-I236 HydrophobicContact CZ-CG1 4.14Å; F232-I236 PolarHBondContact O-N 2.68Å; L233-I236 VanDerWaalsContact O-CG2 3.28Å; L233-I236 WeakPolarHBondContact O-CG2 3.46Å; L233-I236 PolarHBondContact O-N 3.44Å; I236-T431 HydrophobicContact CG1-CG2 3.68Å; I236-T431 WeakPolarHBondContact O-CG2 3.34Å; I236-T431 PolarHBondContact O-OG1 3.44Å
237	R	89.4	Confident	93.1	Very high	206 Å²	206	45 Å²	45	78%	0.777	21%	0.207	S	C	*	.	T	Hydrogen-bonded Turn	trans	-111.9	23.9	172.2	-58.1	-179.6	-179.5	170.2	-0.2	113	L235	L235-R237 PolarHBondContact O-N 3.37Å; L235-R237 VanDerWaalsContact O-N 3.09Å
238	G	89.1	Confident	93	Very high	3 Å²	3	49.6 Å²	49.6	3%	0.031	23%	0.227	C	C	.	.	T	Hydrogen-bonded Turn	trans	57.8	-141.3	-175.8	0	0	0	0	0	112.6	L235 K240 S241 S242	L235-G238 WeakPolarHBondContact O-CA 3.14Å; L235-G238 PolarHBondContact O-N 3.41Å; G238-K240 PolarHBondContact O-N 3.47Å; G238-S241 PolarHBondContact O-N 2.98Å; G238-S242 PolarHBondContact O-N 3.46Å; G238-S242 VanDerWaalsContact O-N 3.1Å; G238-S242 PolarHBondContact O-OG 3.41Å
239	V	87.6	Confident	92.8	Very high	6 Å²	6	49 Å²	49	4%	0.036	23%	0.226	C	C	.	.	H	α-helix	trans	-53.4	-27.1	-178.4	-63.1	0	0	0	0	115.3	W31 S241 S242 G243 Y315 E411	W31-V239 HydrophobicContact CD2-CB 4.49Å; W31-V239 HydrophobicContact CE3-CB 4.06Å; W31-V239 HydrophobicContact CH2-CB 3.75Å; W31-V239 HydrophobicContact CH2-CG1 3.65Å; W31-V239 HydrophobicContact CZ2-CB 4.23Å; W31-V239 HydrophobicContact CZ2-CG1 3.9Å; W31-V239 HydrophobicContact CZ3-CB 3.67Å; W31-V239 HydrophobicContact CZ3-CG1 4.14Å; W31-V239 WeakPolarHBondContact CZ3-O 3.42Å; V239-S241 VanDerWaalsContact C-N 3.34Å; V239-S242 WeakPolarHBondContact CA-OG 3.43Å; V239-G243 WeakPolarHBondContact O-CA 3.35Å; V239-G243 PolarHBondContact O-N 3.33Å; V239-Y315 HydrophobicContact CG1-CD1 4.29Å; V239-Y315 HydrophobicContact CG1-CD2 3.56Å; V239-Y315 HydrophobicContact CG1-CE1 4.39Å; V239-Y315 HydrophobicContact CG1-CE2 3.66Å; V239-Y315 HydrophobicContact CG1-CG 3.91Å; V239-Y315 HydrophobicContact CG2-CD1 3.89Å; V239-Y315 HydrophobicContact CG2-CE1 4.19Å; V239-Y315 HydrophobicContact CG2-CG 4.12Å; V239-E411 HydrophobicContact CG1-CG 4.3Å
240	K	88.5	Confident	92.6	Very high	103 Å²	103	43.6 Å²	43.6	45%	0.448	20%	0.203	S	C	.	.	H	α-helix	trans	-71.6	-28.6	177.6	-65.4	-167.7	178.5	-173.6	0	113.1	D23 G238	D23-K240 IonicContact OD1-NZ 4Å; D23-K240 WeakPolarHBondContact OD2-CE 3.25Å; D23-K240 IonicContact OD2-NZ 3.8Å; D23-K240 PolarHBondContact OD2-NZ 3.26Å; G238-K240 PolarHBondContact O-N 3.47Å
241	S	92	Very high	92.4	Very high	24 Å²	24	44.9 Å²	44.9	17%	0.168	21%	0.211	C	C	.	.	H	α-helix	trans	-87.8	-49.8	175.9	179.7	0	0	0	0	110.7	C234 G238 V239 G243 K244 V245	C234-S241 CarbonylContact O-C 3.59Å; C234-S241 VanDerWaalsContact O-CB 3.23Å; C234-S241 WeakPolarHBondContact O-CB 3.37Å; C234-S241 PolarHBondContact O-OG 2.89Å; G238-S241 PolarHBondContact O-N 2.98Å; V239-S241 VanDerWaalsContact C-N 3.34Å; S241-G243 VanDerWaalsContact C-N 3.29Å; S241-G243 PolarHBondContact O-N 2.93Å; S241-K244 PolarHBondContact O-N 3.35Å; S241-V245 WeakPolarHBondContact O-CG2 3.41Å; S241-V245 PolarHBondContact O-N 2.9Å; S241-V245 VanDerWaalsContact O-N 3.08Å
242	S	91.8	Very high	92.3	Very high	3 Å²	3	47.2 Å²	47.2	2%	0.021	22%	0.221	C	C	.	.	H	α-helix	trans	-62.7	-36.8	-179.1	58	0	0	0	0	112.3	C234 G238 V239 K244 V245 V246	C234-S242 PolarHBondContact O-N 2.56Å; G238-S242 PolarHBondContact O-N 3.46Å; G238-S242 VanDerWaalsContact O-N 3.1Å; G238-S242 PolarHBondContact O-OG 3.41Å; V239-S242 WeakPolarHBondContact CA-OG 3.43Å; S242-K244 PolarHBondContact O-N 2.77Å; S242-V245 PolarHBondContact O-N 3.36Å; S242-V246 WeakPolarHBondContact O-CB 3.31Å; S242-V246 PolarHBondContact O-N 3.19Å
243	G	89.2	Confident	92.3	Very high	0 Å²	0	46 Å²	46	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-62	-21	174.1	0	0	0	0	0	114.5	E36 V239 S241 V246 Y247	E36-G243 WeakPolarHBondContact CG-O 3.07Å; V239-G243 WeakPolarHBondContact O-CA 3.35Å; V239-G243 PolarHBondContact O-N 3.33Å; S241-G243 VanDerWaalsContact C-N 3.29Å; S241-G243 PolarHBondContact O-N 2.93Å; G243-V246 WeakPolarHBondContact O-CG1 3.28Å; G243-Y247 WeakPolarHBondContact O-CD2 3.41Å; G243-Y247 WeakPolarHBondContact O-CE2 3.43Å
244	K	92.7	Very high	92.2	Very high	117 Å²	117	45.5 Å²	45.5	51%	0.509	21%	0.21	S	C	.	.	H	α-helix	trans	-89	-43.2	172.7	-63.5	-57.2	-172.3	-168.6	0	112.1	E36 S241 S242 V246 Y247	E36-K244 VanDerWaalsContact OE1-CE 3.27Å; E36-K244 WeakPolarHBondContact OE1-CE 3.24Å; E36-K244 IonicContact OE1-NZ 2.85Å; E36-K244 PolarHBondContact OE1-NZ 2.83Å; S241-K244 PolarHBondContact O-N 3.35Å; S242-K244 PolarHBondContact O-N 2.77Å; K244-V246 PolarHBondContact O-N 3.48Å; K244-Y247 WeakPolarHBondContact O-CD2 3.49Å; K244-Y247 PolarHBondContact O-N 2.96Å
245	V	93.5	Very high	92.3	Very high	42 Å²	42	48.2 Å²	48.2	26%	0.255	23%	0.226	S	C	.	.	H	α-helix	trans	-60.9	-35.6	178.1	173.9	0	0	0	0	111.1	C234 S241 S242 Y247 F248 T249 F407	C234-V245 HydrophobicContact CB-CG1 4.38Å; C234-V245 HydrophobicContact CB-CG2 4.39Å; S241-V245 WeakPolarHBondContact O-CG2 3.41Å; S241-V245 PolarHBondContact O-N 2.9Å; S241-V245 VanDerWaalsContact O-N 3.08Å; S242-V245 PolarHBondContact O-N 3.36Å; V245-Y247 PolarHBondContact O-N 2.89Å; V245-F248 PolarHBondContact O-N 3.01Å; V245-T249 HydrophobicContact CG1-CG2 3.57Å; V245-T249 PolarHBondContact O-N 3.41Å; V245-T249 VanDerWaalsContact O-N 3.11Å; V245-F407 HydrophobicContact CG1-CE2 3.94Å; V245-F407 HydrophobicContact CG1-CZ 4.18Å
246	V	92.9	Very high	92.3	Very high	3 Å²	3	48.2 Å²	48.2	2%	0.018	23%	0.226	C	C	.	.	H	α-helix	trans	-65	-22.5	-176.2	76.9	0	0	0	0	114.7	L39 S242 G243 K244 F248 T249 A250	L39-V246 HydrophobicContact CB-CG1 3.88Å; L39-V246 HydrophobicContact CB-CG2 4.16Å; L39-V246 WeakPolarHBondContact O-CG2 3.23Å; S242-V246 WeakPolarHBondContact O-CB 3.31Å; S242-V246 PolarHBondContact O-N 3.19Å; G243-V246 WeakPolarHBondContact O-CG1 3.28Å; K244-V246 PolarHBondContact O-N 3.48Å; V246-F248 PolarHBondContact O-N 2.94Å; V246-T249 WeakPolarHBondContact CA-OG1 3.21Å; V246-T249 PolarHBondContact O-N 3.42Å; V246-A250 HydrophobicContact CG2-CB 3.6Å; V246-A250 VanDerWaalsContact O-CB 3.27Å; V246-A250 WeakPolarHBondContact O-CB 3.36Å; V246-A250 PolarHBondContact O-N 2.99Å
247	Y	93.4	Very high	92.3	Very high	82 Å²	82	45.4 Å²	45.4	32%	0.322	21%	0.211	S	C	.	.	H	α-helix	trans	-56.4	-35	172.2	-79.7	-79.7	0	0	0	111.8	I35 E36 L39 G243 K244 V245 T251	I35-Y247 HydrophobicContact CG2-CE1 3.7Å; E36-Y247 HydrophobicContact CG-CE2 3.75Å; L39-Y247 HydrophobicContact CD1-CD1 3.6Å; L39-Y247 HydrophobicContact CD1-CE1 3.79Å; L39-Y247 HydrophobicContact CD1-CG 4.22Å; G243-Y247 WeakPolarHBondContact O-CD2 3.41Å; G243-Y247 WeakPolarHBondContact O-CE2 3.43Å; K244-Y247 WeakPolarHBondContact O-CD2 3.49Å; K244-Y247 PolarHBondContact O-N 2.96Å; V245-Y247 PolarHBondContact O-N 2.89Å; Y247-T251 WeakPolarHBondContact O-CB 3.38Å; Y247-T251 WeakPolarHBondContact O-CG2 3.37Å; Y247-T251 PolarHBondContact O-OG1 3.47Å
248	F	94.8	Very high	92.6	Very high	96 Å²	96	38.3 Å²	38.3	42%	0.421	19%	0.191	S	C	.	.	H	α-helix	trans	-88.2	-51.8	174.9	-178.3	-103.8	0	0	0	111.4	V245 V246 A250 T251 F252 F396 L400	V245-F248 PolarHBondContact O-N 3.01Å; V246-F248 PolarHBondContact O-N 2.94Å; F248-A250 VanDerWaalsContact C-N 3.3Å; F248-A250 PolarHBondContact O-N 3.27Å; F248-T251 PolarHBondContact O-N 2.95Å; F248-F252 HydrophobicContact CD2-CB 4.18Å; F248-F252 HydrophobicContact CD2-CD2 4.41Å; F248-F252 HydrophobicContact CE1-CB 4.5Å; F248-F252 HydrophobicContact CE2-CB 3.91Å; F248-F252 AromaticContact CE2-CD2 3.51Å; F248-F252 HydrophobicContact CE2-CD2 3.51Å; F248-F252 HydrophobicContact CE2-CE2 4.21Å; F248-F252 AromaticContact CE2-CG 3.8Å; F248-F252 HydrophobicContact CE2-CG 3.8Å; F248-F252 HydrophobicContact CZ-CB 4.08Å; F248-F252 HydrophobicContact CZ-CD1 4.31Å; F248-F252 AromaticContact CZ-CD2 3.84Å; F248-F252 HydrophobicContact CZ-CD2 3.84Å; F248-F252 HydrophobicContact CZ-CE2 4.35Å; F248-F252 AromaticContact CZ-CG 3.8Å; F248-F252 HydrophobicContact CZ-CG 3.8Å; F248-F252 VanDerWaalsContact O-CB 3.28Å; F248-F252 WeakPolarHBondContact O-CB 3.15Å; F248-F252 PolarHBondContact O-N 3.19Å; F248-F396 HydrophobicContact CE1-CE1 4.05Å; F248-F396 AromaticContact CE1-CZ 3.76Å; F248-F396 HydrophobicContact CE1-CZ 3.76Å; F248-F396 AromaticContact CZ-CE1 3.82Å; F248-F396 HydrophobicContact CZ-CE1 3.82Å; F248-F396 AromaticContact CZ-CZ 3.9Å; F248-F396 HydrophobicContact CZ-CZ 3.9Å; F248-L400 HydrophobicContact CD1-CD2 4.12Å; F248-L400 HydrophobicContact CE1-CD1 3.89Å; F248-L400 HydrophobicContact CE1-CD2 3.85Å; F248-L400 HydrophobicContact CZ-CD1 4.39Å
249	T	92.9	Very high	92.9	Very high	6 Å²	6	41.6 Å²	41.6	4%	0.037	21%	0.207	C	C	.	.	H	α-helix	trans	-66.8	-28.3	-171.2	66.8	0	0	0	0	113.5	V245 V246 P253 L400 F407	V245-T249 HydrophobicContact CG1-CG2 3.57Å; V245-T249 PolarHBondContact O-N 3.41Å; V245-T249 VanDerWaalsContact O-N 3.11Å; V246-T249 WeakPolarHBondContact CA-OG1 3.21Å; V246-T249 PolarHBondContact O-N 3.42Å; T249-P253 WeakPolarHBondContact O-CD 3.33Å; T249-P253 VanDerWaalsContact O-CG 3.27Å; T249-P253 WeakPolarHBondContact O-CG 3.47Å; T249-L400 HydrophobicContact CG2-CD2 3.84Å; T249-F407 HydrophobicContact CG2-CE2 4.3Å
250	A	91.8	Very high	93.1	Very high	7 Å²	7	41.4 Å²	41.4	6%	0.058	21%	0.206	C	C	.	.	T	Hydrogen-bonded Turn	trans	-87.9	-27.7	175.6	0	0	0	0	0	113.5	V246 F248 Y254	V246-A250 HydrophobicContact CG2-CB 3.6Å; V246-A250 VanDerWaalsContact O-CB 3.27Å; V246-A250 WeakPolarHBondContact O-CB 3.36Å; V246-A250 PolarHBondContact O-N 2.99Å; F248-A250 VanDerWaalsContact C-N 3.3Å; F248-A250 PolarHBondContact O-N 3.27Å; A250-Y254 WeakPolarHBondContact O-CD2 3.15Å; A250-Y254 WeakPolarHBondContact O-CE2 3.37Å
251	T	93	Very high	93.4	Very high	63 Å²	63	39 Å²	39	39%	0.387	20%	0.195	S	C	.	.	T	Hydrogen-bonded Turn	trans	-92.6	-38.9	-174.8	65.3	0	0	0	0	113	Y247 F248 P253 Y254	Y247-T251 WeakPolarHBondContact O-CB 3.38Å; Y247-T251 WeakPolarHBondContact O-CG2 3.37Å; Y247-T251 PolarHBondContact O-OG1 3.47Å; F248-T251 PolarHBondContact O-N 2.95Å; T251-P253 VanDerWaalsContact C-CD 3.49Å; T251-Y254 WeakPolarHBondContact O-CB 3.39Å; T251-Y254 PolarHBondContact O-N 2.99Å
252	F	94.4	Very high	93.5	Very high	49 Å²	49	42.4 Å²	42.4	22%	0.215	21%	0.211	C	C	.	.	H	α-helix	trans	-60.8	-36.1	-176.4	-170	-90.7	0	0	0	113.8	F248 Y254 V255 V256 F396 L400	F248-F252 HydrophobicContact CD2-CB 4.18Å; F248-F252 HydrophobicContact CD2-CD2 4.41Å; F248-F252 HydrophobicContact CE1-CB 4.5Å; F248-F252 HydrophobicContact CE2-CB 3.91Å; F248-F252 AromaticContact CE2-CD2 3.51Å; F248-F252 HydrophobicContact CE2-CD2 3.51Å; F248-F252 HydrophobicContact CE2-CE2 4.21Å; F248-F252 AromaticContact CE2-CG 3.8Å; F248-F252 HydrophobicContact CE2-CG 3.8Å; F248-F252 HydrophobicContact CZ-CB 4.08Å; F248-F252 HydrophobicContact CZ-CD1 4.31Å; F248-F252 AromaticContact CZ-CD2 3.84Å; F248-F252 HydrophobicContact CZ-CD2 3.84Å; F248-F252 HydrophobicContact CZ-CE2 4.35Å; F248-F252 AromaticContact CZ-CG 3.8Å; F248-F252 HydrophobicContact CZ-CG 3.8Å; F248-F252 VanDerWaalsContact O-CB 3.28Å; F248-F252 WeakPolarHBondContact O-CB 3.15Å; F248-F252 PolarHBondContact O-N 3.19Å; F252-Y254 PolarHBondContact O-N 2.91Å; F252-V255 WeakPolarHBondContact O-CB 3.28Å; F252-V255 PolarHBondContact O-N 3.08Å; F252-V256 HydrophobicContact CD1-CG2 3.78Å; F252-V256 HydrophobicContact CE1-CG2 3.31Å; F252-V256 HydrophobicContact CZ-CG2 4.01Å; F252-V256 PolarHBondContact O-N 2.88Å; F252-V256 VanDerWaalsContact O-N 3.09Å; F252-F396 HydrophobicContact CD1-CD1 4.01Å; F252-F396 AromaticContact CD1-CE1 3.88Å; F252-F396 HydrophobicContact CD1-CE1 3.88Å; F252-F396 AromaticContact CE1-CD1 3.46Å; F252-F396 HydrophobicContact CE1-CD1 3.46Å; F252-F396 VanDerWaalsContact CE1-CD1 3.46Å; F252-F396 AromaticContact CE1-CE1 3.56Å; F252-F396 HydrophobicContact CE1-CE1 3.56Å; F252-F396 HydrophobicContact CZ-CD1 4.19Å; F252-F396 HydrophobicContact CZ-CE1 4.08Å; F252-L400 HydrophobicContact CB-CD1 3.9Å; F252-L400 HydrophobicContact CD1-CD1 3.45Å; F252-L400 VanDerWaalsContact CD1-CD1 3.45Å; F252-L400 HydrophobicContact CE1-CD1 4.36Å; F252-L400 HydrophobicContact CG-CD1 4Å
253	P	94.4	Very high	93.6	Very high	2 Å²	2	45.2 Å²	45.2	1%	0.013	22%	0.221	C	C	.	.	H	α-helix	trans	-54.7	-36.1	172.3	-30.3	38.3	0	0	0	114	T249 T251 V255 V256 L257 M397 L400 L401	T249-P253 WeakPolarHBondContact O-CD 3.33Å; T249-P253 VanDerWaalsContact O-CG 3.27Å; T249-P253 WeakPolarHBondContact O-CG 3.47Å; T251-P253 VanDerWaalsContact C-CD 3.49Å; P253-V255 VanDerWaalsContact C-N 3.34Å; P253-V255 PolarHBondContact O-N 3.35Å; P253-V256 PolarHBondContact O-N 3.49Å; P253-L257 WeakPolarHBondContact O-CB 3.49Å; P253-L257 VanDerWaalsContact O-CG 3.29Å; P253-L257 WeakPolarHBondContact O-CG 3.41Å; P253-L257 PolarHBondContact O-N 2.92Å; P253-M397 HydrophobicContact CB-CG 3.93Å; P253-L400 HydrophobicContact CG-CB 3.93Å; P253-L401 HydrophobicContact CB-CD1 4.47Å; P253-L401 HydrophobicContact CB-CD2 3.59Å; P253-L401 HydrophobicContact CB-CG 3.87Å; P253-L401 HydrophobicContact CG-CD2 3.77Å; P253-L401 HydrophobicContact CG-CG 3.96Å
254	Y	94.3	Very high	93.8	Very high	63 Å²	63	45.2 Å²	45.2	25%	0.247	22%	0.221	C	C	.	.	H	α-helix	trans	-67.9	-34.3	176.7	-65.2	-81.3	0	0	0	112.5	A250 T251 F252 T258 T335 T339	A250-Y254 WeakPolarHBondContact O-CD2 3.15Å; A250-Y254 WeakPolarHBondContact O-CE2 3.37Å; T251-Y254 WeakPolarHBondContact O-CB 3.39Å; T251-Y254 PolarHBondContact O-N 2.99Å; F252-Y254 PolarHBondContact O-N 2.91Å; Y254-T258 WeakPolarHBondContact O-CB 3.37Å; Y254-T258 PolarHBondContact O-N 3Å; Y254-T258 PolarHBondContact O-OG1 2.98Å; Y254-T335 WeakPolarHBondContact OH-CG2 3.23Å; Y254-T339 HydrophobicContact CE1-CG2 3.82Å; Y254-T339 VanDerWaalsContact CE1-OG1 3.28Å; Y254-T339 WeakPolarHBondContact CE1-OG1 3.48Å; Y254-T339 PolarHBondContact OH-OG1 2.86Å
255	V	95.6	Very high	93.9	Very high	75 Å²	75	43.5 Å²	43.5	46%	0.455	22%	0.216	S	C	.	.	H	α-helix	trans	-62.6	-48.8	173.5	-179.8	0	0	0	0	109.6	F252 P253 T258 I259	F252-V255 WeakPolarHBondContact O-CB 3.28Å; F252-V255 PolarHBondContact O-N 3.08Å; P253-V255 VanDerWaalsContact C-N 3.34Å; P253-V255 PolarHBondContact O-N 3.35Å; V255-T258 PolarHBondContact O-N 3.34Å; V255-I259 HydrophobicContact CG1-CD1 3.93Å; V255-I259 WeakPolarHBondContact O-CG1 3.48Å; V255-I259 PolarHBondContact O-N 2.83Å
256	V	94.3	Very high	93.9	Very high	1 Å²	1	45.5 Å²	45.5	1%	0.006	23%	0.229	C	C	.	.	H	α-helix	trans	-64.3	-45.7	178.9	178.5	0	0	0	0	111.7	F252 P253 T258 I259 L260 L393 M397	F252-V256 HydrophobicContact CD1-CG2 3.78Å; F252-V256 HydrophobicContact CE1-CG2 3.31Å; F252-V256 HydrophobicContact CZ-CG2 4.01Å; F252-V256 PolarHBondContact O-N 2.88Å; F252-V256 VanDerWaalsContact O-N 3.09Å; P253-V256 PolarHBondContact O-N 3.49Å; V256-T258 PolarHBondContact O-N 3.45Å; V256-I259 PolarHBondContact O-N 2.67Å; V256-L260 HydrophobicContact CG1-CD1 3.84Å; V256-L260 HydrophobicContact CG1-CG 4.17Å; V256-L260 WeakPolarHBondContact O-CB 3.47Å; V256-L260 WeakPolarHBondContact O-CG 3.41Å; V256-L260 PolarHBondContact O-N 3.48Å; V256-L393 HydrophobicContact CG1-CB 4.12Å; V256-M397 HydrophobicContact CB-CB 4.01Å; V256-M397 HydrophobicContact CB-CG 4.25Å; V256-M397 HydrophobicContact CB-SD 4.07Å; V256-M397 HydrophobicContact CG1-CB 3.83Å; V256-M397 HydrophobicContact CG1-CG 4.28Å; V256-M397 HydrophobicContact CG1-SD 3.82Å; V256-M397 HydrophobicContact CG2-CB 4.26Å
257	L	93.6	Very high	93.9	Very high	2 Å²	2	46 Å²	46	1%	0.01	23%	0.231	C	C	.	.	H	α-helix	trans	-57.5	-39.3	175.6	-74.2	173.9	0	0	0	111.3	P253 F261 T339 Y342 A343 V346 M397	P253-L257 WeakPolarHBondContact O-CB 3.49Å; P253-L257 VanDerWaalsContact O-CG 3.29Å; P253-L257 WeakPolarHBondContact O-CG 3.41Å; P253-L257 PolarHBondContact O-N 2.92Å; L257-F261 WeakPolarHBondContact O-CB 3.42Å; L257-F261 PolarHBondContact O-N 3.36Å; L257-T339 HydrophobicContact CD1-CG2 4.3Å; L257-Y342 HydrophobicContact CB-CD1 4.24Å; L257-Y342 HydrophobicContact CB-CE1 3.8Å; L257-Y342 HydrophobicContact CD1-CD1 4.39Å; L257-A343 HydrophobicContact CD2-CB 4.4Å; L257-V346 HydrophobicContact CB-CG2 4.39Å; L257-V346 HydrophobicContact CD2-CB 4.44Å; L257-V346 HydrophobicContact CD2-CG1 4.38Å; L257-V346 HydrophobicContact CD2-CG2 4.17Å; L257-V346 WeakPolarHBondContact O-CG2 3.49Å; L257-M397 HydrophobicContact CD2-CE 4.24Å; L257-M397 HydrophobicContact CD2-SD 3.62Å; L257-M397 HydrophobicContact CG-SD 3.69Å
258	T	95.3	Very high	93.8	Very high	58 Å²	58	47.8 Å²	47.8	36%	0.356	25%	0.246	S	C	.	.	H	α-helix	trans	-67.9	-42.8	177.7	-54	0	0	0	0	112.2	Y254 V255 V256 F261 I262 Y342	Y254-T258 WeakPolarHBondContact O-CB 3.37Å; Y254-T258 PolarHBondContact O-N 3Å; Y254-T258 PolarHBondContact O-OG1 2.98Å; V255-T258 PolarHBondContact O-N 3.34Å; V256-T258 PolarHBondContact O-N 3.45Å; T258-F261 WeakPolarHBondContact O-CB 3.5Å; T258-F261 PolarHBondContact O-N 3.08Å; T258-I262 HydrophobicContact CG2-CD1 4.1Å; T258-I262 WeakPolarHBondContact O-CG1 3.44Å; T258-I262 PolarHBondContact O-N 2.95Å; T258-Y342 VanDerWaalsContact CA-OH 3.3Å; T258-Y342 WeakPolarHBondContact CA-OH 3.29Å; T258-Y342 PolarHBondContact OG1-OH 3.5Å
259	I	94.9	Very high	93.6	Very high	71 Å²	71	44 Å²	44	36%	0.364	24%	0.235	S	C	.	.	H	α-helix	trans	-62.5	-46.5	175.9	-69.5	166.7	0	0	0	110.5	V255 V256 F261 I262 R263 W390	V255-I259 HydrophobicContact CG1-CD1 3.93Å; V255-I259 WeakPolarHBondContact O-CG1 3.48Å; V255-I259 PolarHBondContact O-N 2.83Å; V256-I259 PolarHBondContact O-N 2.67Å; I259-F261 VanDerWaalsContact C-N 3.33Å; I259-F261 PolarHBondContact O-N 3.1Å; I259-I262 PolarHBondContact O-N 2.95Å; I259-R263 WeakPolarHBondContact O-CB 3.38Å; I259-R263 PolarHBondContact O-N 2.86Å; I259-W390 HydrophobicContact CG2-CZ3 3.83Å
260	L	92.3	Very high	93.6	Very high	2 Å²	2	43.9 Å²	43.9	1%	0.01	23%	0.234	C	C	.	.	H	α-helix	trans	-67	-33.6	177	-70.3	176.9	0	0	0	112.3	V256 G264 V346 I350 W390 F394	V256-L260 HydrophobicContact CG1-CD1 3.84Å; V256-L260 HydrophobicContact CG1-CG 4.17Å; V256-L260 WeakPolarHBondContact O-CB 3.47Å; V256-L260 WeakPolarHBondContact O-CG 3.41Å; V256-L260 PolarHBondContact O-N 3.48Å; L260-G264 WeakPolarHBondContact O-CA 3.24Å; L260-G264 PolarHBondContact O-N 2.8Å; L260-V346 HydrophobicContact CB-CG1 3.61Å; L260-I350 HydrophobicContact CD2-CD1 4.49Å; L260-W390 HydrophobicContact CD2-CE3 3.76Å; L260-W390 HydrophobicContact CD2-CZ3 4.31Å; L260-F394 HydrophobicContact CD1-CD2 4.09Å
261	F	94.4	Very high	93.7	Very high	52 Å²	52	49 Å²	49	23%	0.228	26%	0.259	C	S	.	.	H	α-helix	trans	-62.8	-53.9	174	-179.9	-115.9	0	0	0	111	L257 T258 I259 R263 G264 I265 Y342 F345 V346	L257-F261 WeakPolarHBondContact O-CB 3.42Å; L257-F261 PolarHBondContact O-N 3.36Å; T258-F261 WeakPolarHBondContact O-CB 3.5Å; T258-F261 PolarHBondContact O-N 3.08Å; I259-F261 VanDerWaalsContact C-N 3.33Å; I259-F261 PolarHBondContact O-N 3.1Å; F261-R263 VanDerWaalsContact C-N 3.29Å; F261-R263 PolarHBondContact O-N 3.37Å; F261-G264 PolarHBondContact O-N 2.84Å; F261-G264 VanDerWaalsContact O-N 3.16Å; F261-I265 HydrophobicContact CD2-CG2 4.04Å; F261-I265 HydrophobicContact CE1-CD1 4.05Å; F261-I265 HydrophobicContact CE2-CG2 3.59Å; F261-I265 HydrophobicContact CZ-CD1 4.26Å; F261-I265 HydrophobicContact CZ-CG2 3.87Å; F261-I265 WeakPolarHBondContact O-CG1 3.41Å; F261-I265 PolarHBondContact O-N 2.9Å; F261-Y342 HydrophobicContact CB-CE2 4.47Å; F261-Y342 WeakPolarHBondContact CB-OH 3.23Å; F261-Y342 HydrophobicContact CD1-CE2 4.24Å; F261-Y342 HydrophobicContact CD2-CE2 4.39Å; F261-Y342 HydrophobicContact CG-CE2 4.1Å; F261-F345 HydrophobicContact CD2-CB 4.24Å; F261-F345 HydrophobicContact CE2-CB 3.94Å; F261-V346 HydrophobicContact CB-CG2 3.78Å; F261-V346 HydrophobicContact CD2-CG2 4.29Å; F261-V346 HydrophobicContact CG-CG2 4.47Å
262	I	95.2	Very high	93.6	Very high	96 Å²	96	49.9 Å²	49.9	49%	0.492	26%	0.262	S	S	.	.	H	α-helix	trans	-59	-45.5	179.6	-67	165.7	0	0	0	109.5	T258 I259 I265 T266	T258-I262 HydrophobicContact CG2-CD1 4.1Å; T258-I262 WeakPolarHBondContact O-CG1 3.44Å; T258-I262 PolarHBondContact O-N 2.95Å; I259-I262 PolarHBondContact O-N 2.95Å; I262-I265 WeakPolarHBondContact O-CG1 3.32Å; I262-T266 WeakPolarHBondContact O-CG2 3.42Å; I262-T266 PolarHBondContact O-N 2.87Å; I262-T266 PolarHBondContact O-OG1 2.79Å
263	R	93.5	Very high	93.5	Very high	63 Å²	63	47.5 Å²	47.5	24%	0.238	25%	0.251	C	S	.	.	H	α-helix	trans	-62.3	-48.1	176	-178.4	59.2	-176.8	143.4	-2	111.3	I259 F261 I265 T266 L267 L384 P385 W390	I259-R263 WeakPolarHBondContact O-CB 3.38Å; I259-R263 PolarHBondContact O-N 2.86Å; F261-R263 VanDerWaalsContact C-N 3.29Å; F261-R263 PolarHBondContact O-N 3.37Å; R263-I265 PolarHBondContact O-N 3.15Å; R263-T266 PolarHBondContact NH1-OG1 3.36Å; R263-T266 PolarHBondContact O-N 2.97Å; R263-T266 VanDerWaalsContact O-N 3.14Å; R263-T266 PolarHBondContact O-OG1 3.43Å; R263-L267 WeakPolarHBondContact O-CG 3.23Å; R263-L384 HydrophobicContact CG-CD1 4.5Å; R263-P385 VanDerWaalsContact NH2-CD 3.28Å; R263-W390 HydrophobicContact CB-CH2 3.61Å; R263-W390 HydrophobicContact CB-CZ2 4.43Å; R263-W390 HydrophobicContact CB-CZ3 3.66Å; R263-W390 HydrophobicContact CG-CE3 4.36Å; R263-W390 HydrophobicContact CG-CH2 3.48Å; R263-W390 VanDerWaalsContact CG-CH2 3.48Å; R263-W390 HydrophobicContact CG-CZ2 3.8Å; R263-W390 HydrophobicContact CG-CZ3 3.77Å
264	G	92.4	Very high	93.5	Very high	0 Å²	0	49.1 Å²	49.1	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-57.2	-46.4	-177.2	0	0	0	0	0	113.1	L260 F261 T266 L267 A270 S349	L260-G264 WeakPolarHBondContact O-CA 3.24Å; L260-G264 PolarHBondContact O-N 2.8Å; F261-G264 PolarHBondContact O-N 2.84Å; F261-G264 VanDerWaalsContact O-N 3.16Å; G264-T266 VanDerWaalsContact C-N 3.28Å; G264-T266 PolarHBondContact O-N 3.36Å; G264-L267 WeakPolarHBondContact O-CB 3.36Å; G264-L267 PolarHBondContact O-N 3.24Å; G264-A270 WeakPolarHBondContact O-CB 3.49Å; G264-S349 WeakPolarHBondContact CA-OG 3.21Å
265	I	95.3	Very high	93.3	Very high	81 Å²	81	52 Å²	52	42%	0.415	27%	0.273	S	S	.	.	H	α-helix	trans	-71.8	-19.2	179.4	67.1	177.9	0	0	0	113.8	F261 I262 R263 L267 I274	F261-I265 HydrophobicContact CD2-CG2 4.04Å; F261-I265 HydrophobicContact CE1-CD1 4.05Å; F261-I265 HydrophobicContact CE2-CG2 3.59Å; F261-I265 HydrophobicContact CZ-CD1 4.26Å; F261-I265 HydrophobicContact CZ-CG2 3.87Å; F261-I265 WeakPolarHBondContact O-CG1 3.41Å; F261-I265 PolarHBondContact O-N 2.9Å; I262-I265 WeakPolarHBondContact O-CG1 3.32Å; R263-I265 PolarHBondContact O-N 3.15Å; I265-L267 VanDerWaalsContact C-N 3.27Å; I265-I274 HydrophobicContact CG2-CD1 4.2Å
266	T	93.7	Very high	93	Very high	83 Å²	83	52.4 Å²	52.4	51%	0.509	27%	0.267	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.2	-6.6	175.3	63.4	0	0	0	0	113.4	I262 R263 G264	I262-T266 WeakPolarHBondContact O-CG2 3.42Å; I262-T266 PolarHBondContact O-N 2.87Å; I262-T266 PolarHBondContact O-OG1 2.79Å; R263-T266 PolarHBondContact NH1-OG1 3.36Å; R263-T266 PolarHBondContact O-N 2.97Å; R263-T266 VanDerWaalsContact O-N 3.14Å; R263-T266 PolarHBondContact O-OG1 3.43Å; G264-T266 VanDerWaalsContact C-N 3.28Å; G264-T266 PolarHBondContact O-N 3.36Å
267	L	92.6	Very high	92.9	Very high	14 Å²	14	52.3 Å²	52.3	7%	0.073	27%	0.267	C	S	.	.	S	Bend	trans	-86.5	146.3	-179.4	-63.9	165.8	0	0	0	111.5	R263 G264 I265 A270 F353 L384	R263-L267 WeakPolarHBondContact O-CG 3.23Å; G264-L267 WeakPolarHBondContact O-CB 3.36Å; G264-L267 PolarHBondContact O-N 3.24Å; I265-L267 VanDerWaalsContact C-N 3.27Å; L267-A270 VanDerWaalsContact O-CB 3.25Å; L267-A270 WeakPolarHBondContact O-CB 3.41Å; L267-A270 PolarHBondContact O-N 2.89Å; L267-F353 HydrophobicContact CB-CB 3.78Å; L267-F353 HydrophobicContact CB-CD2 3.7Å; L267-F353 HydrophobicContact CB-CE2 4.36Å; L267-F353 HydrophobicContact CB-CG 3.76Å; L267-F353 HydrophobicContact CD1-CB 4.01Å; L267-F353 HydrophobicContact CD1-CD1 3.77Å; L267-F353 HydrophobicContact CD1-CD2 4.43Å; L267-F353 HydrophobicContact CD1-CE1 4.27Å; L267-F353 HydrophobicContact CD1-CG 3.83Å; L267-F353 HydrophobicContact CD2-CD1 4.45Å; L267-F353 HydrophobicContact CD2-CD2 4.18Å; L267-F353 HydrophobicContact CD2-CE1 4.29Å; L267-F353 HydrophobicContact CD2-CE2 4.04Å; L267-F353 HydrophobicContact CD2-CG 4.37Å; L267-F353 HydrophobicContact CD2-CZ 4.09Å; L267-F353 HydrophobicContact CG-CB 4.48Å; L267-F353 HydrophobicContact CG-CD1 4.46Å; L267-F353 HydrophobicContact CG-CD2 4.31Å; L267-F353 HydrophobicContact CG-CG 4.18Å; L267-L384 HydrophobicContact CD1-CD2 3.5Å; L267-L384 VanDerWaalsContact CD1-CD2 3.5Å; L267-L384 HydrophobicContact CD2-CD2 3.66Å; L267-L384 HydrophobicContact CG-CD2 4.21Å
268	D	92.2	Very high	92.8	Very high	119 Å²	119	55.6 Å²	55.6	64%	0.636	28%	0.284	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.7	137.8	175.5	-60.6	-45.9	0	0	0	110.7	A270 F353	D268-A270 PolarHBondContact O-N 3.34Å; D268-F353 WeakPolarHBondContact O-CA 3.46Å; D268-F353 WeakPolarHBondContact O-CD2 3.5Å
269	G	90.7	Very high	92.6	Very high	17 Å²	17	56.7 Å²	56.7	18%	0.175	29%	0.291	C	S	.	.	T	Hydrogen-bonded Turn	trans	77.8	-4.1	-178.5	0	0	0	0	0	115.9	I271 N272 G352	G269-I271 PolarHBondContact O-N 3.36Å; G269-I271 VanDerWaalsContact O-N 3.16Å; G269-N272 WeakPolarHBondContact O-CB 3.37Å; G269-N272 PolarHBondContact O-N 2.86Å; G269-G352 CarbonylContact O-C 3.37Å
270	A	92.8	Very high	92.6	Very high	3 Å²	3	56.1 Å²	56.1	3%	0.025	29%	0.292	C	S	.	.	H	α-helix	trans	-55.6	-35.3	177.1	0	0	0	0	0	113.3	G264 L267 D268 N272 G273 I274 S349	G264-A270 WeakPolarHBondContact O-CB 3.49Å; L267-A270 VanDerWaalsContact O-CB 3.25Å; L267-A270 WeakPolarHBondContact O-CB 3.41Å; L267-A270 PolarHBondContact O-N 2.89Å; D268-A270 PolarHBondContact O-N 3.34Å; A270-N272 PolarHBondContact O-N 3.23Å; A270-G273 PolarHBondContact O-N 2.9Å; A270-I274 PolarHBondContact O-N 3.43Å; A270-I274 VanDerWaalsContact O-N 3.1Å; A270-S349 WeakPolarHBondContact CA-O 3.41Å
271	I	93.3	Very high	92.5	Very high	115 Å²	115	60.7 Å²	60.7	59%	0.59	31%	0.313	S	S	*	.	H	α-helix	trans	-60.2	-34.1	176.5	-66	171.6	0	0	0	111.6	G269 I274 K275	G269-I271 PolarHBondContact O-N 3.36Å; G269-I271 VanDerWaalsContact O-N 3.16Å; I271-I274 PolarHBondContact O-N 2.95Å; I271-K275 HydrophobicContact CG2-CD 3.98Å; I271-K275 HydrophobicContact CG2-CG 4.21Å; I271-K275 WeakPolarHBondContact O-CB 3.35Å; I271-K275 VanDerWaalsContact O-CG 3.3Å; I271-K275 WeakPolarHBondContact O-CG 3.45Å; I271-K275 PolarHBondContact O-N 3.37Å
272	N	91.4	Very high	92.4	Very high	81 Å²	81	65.7 Å²	65.7	43%	0.433	33%	0.33	S	S	.	.	H	α-helix	trans	-66.1	-41.5	-179.8	-65.7	-22	0	0	0	111.1	G269 A270 K275 Y276	G269-N272 WeakPolarHBondContact O-CB 3.37Å; G269-N272 PolarHBondContact O-N 2.86Å; A270-N272 PolarHBondContact O-N 3.23Å; N272-K275 PolarHBondContact O-N 2.96Å; N272-Y276 WeakPolarHBondContact O-CB 3.4Å; N272-Y276 PolarHBondContact O-N 2.88Å
273	G	91.8	Very high	92.3	Very high	0 Å²	0	68.6 Å²	68.6	0%	0	34%	0.342	C	S	.	.	H	α-helix	trans	-67.2	-42.7	175	0	0	0	0	0	112.6	A270 K275 Y276 Y277 F348	A270-G273 PolarHBondContact O-N 2.9Å; G273-K275 VanDerWaalsContact C-N 3.35Å; G273-K275 PolarHBondContact O-N 3.36Å; G273-Y276 WeakPolarHBondContact O-CB 3.43Å; G273-Y276 PolarHBondContact O-N 3.3Å; G273-Y276 VanDerWaalsContact O-N 3.17Å; G273-Y277 PolarHBondContact O-N 3.26Å; G273-F348 VanDerWaalsContact CA-O 3.3Å; G273-F348 WeakPolarHBondContact CA-O 3.44Å
274	I	93.2	Very high	92	Very high	35 Å²	35	70 Å²	70	18%	0.179	35%	0.349	C	S	.	.	H	α-helix	trans	-63.7	-40.8	176.1	-64.7	171.6	0	0	0	111.4	I265 A270 I271 Y276 Y277 L278 F345	I265-I274 HydrophobicContact CG2-CD1 4.2Å; A270-I274 PolarHBondContact O-N 3.43Å; A270-I274 VanDerWaalsContact O-N 3.1Å; I271-I274 PolarHBondContact O-N 2.95Å; I274-Y276 VanDerWaalsContact C-N 3.35Å; I274-Y277 WeakPolarHBondContact O-CB 3.2Å; I274-Y277 PolarHBondContact O-N 2.81Å; I274-L278 HydrophobicContact CG2-CD1 4.04Å; I274-L278 PolarHBondContact O-N 3.23Å; I274-F345 HydrophobicContact CG2-CD1 4.14Å; I274-F345 HydrophobicContact CG2-CE1 3.99Å
275	K	92.1	Very high	91.9	Very high	124 Å²	124	70.9 Å²	70.9	54%	0.539	36%	0.355	S	S	.	.	H	α-helix	trans	-59.7	-48	172.1	-77.7	176.3	179.1	175.5	0	110.3	I271 N272 G273 Y277 L278 T279	I271-K275 HydrophobicContact CG2-CD 3.98Å; I271-K275 HydrophobicContact CG2-CG 4.21Å; I271-K275 WeakPolarHBondContact O-CB 3.35Å; I271-K275 VanDerWaalsContact O-CG 3.3Å; I271-K275 WeakPolarHBondContact O-CG 3.45Å; I271-K275 PolarHBondContact O-N 3.37Å; N272-K275 PolarHBondContact O-N 2.96Å; G273-K275 VanDerWaalsContact C-N 3.35Å; G273-K275 PolarHBondContact O-N 3.36Å; K275-Y277 PolarHBondContact O-N 3.36Å; K275-L278 PolarHBondContact O-N 2.69Å; K275-T279 WeakPolarHBondContact O-CB 3.31Å; K275-T279 PolarHBondContact O-N 2.9Å; K275-T279 PolarHBondContact O-OG1 3.33Å
276	Y	89.2	Confident	91.6	Very high	83 Å²	83	73.7 Å²	73.7	33%	0.325	37%	0.37	S	S	.	.	H	α-helix	trans	-57.2	-38.1	178	-168.2	-99.6	0	0	0	112.7	Y59 N272 G273 I274 F348 V362 S363	Y59-Y276 AromaticContact CD2-CE1 3.98Å; Y59-Y276 HydrophobicContact CD2-CE1 3.98Å; Y59-Y276 HydrophobicContact CG-CE1 4.11Å; N272-Y276 WeakPolarHBondContact O-CB 3.4Å; N272-Y276 PolarHBondContact O-N 2.88Å; G273-Y276 WeakPolarHBondContact O-CB 3.43Å; G273-Y276 PolarHBondContact O-N 3.3Å; G273-Y276 VanDerWaalsContact O-N 3.17Å; I274-Y276 VanDerWaalsContact C-N 3.35Å; Y276-F348 HydrophobicContact CD1-CD1 4.38Å; Y276-F348 AromaticContact CD1-CE1 3.83Å; Y276-F348 HydrophobicContact CD1-CE1 3.83Å; Y276-F348 HydrophobicContact CE1-CE1 4.39Å; Y276-V362 HydrophobicContact CD1-CB 4.04Å; Y276-V362 HydrophobicContact CD1-CG1 3.65Å; Y276-V362 HydrophobicContact CD2-CB 4.28Å; Y276-V362 HydrophobicContact CE1-CG1 4.22Å; Y276-V362 HydrophobicContact CG-CB 3.92Å; Y276-V362 HydrophobicContact CG-CG1 3.95Å; Y276-S363 WeakPolarHBondContact OH-CB 3.49Å
277	Y	91.7	Very high	91.2	Very high	0 Å²	0	73.2 Å²	73.2	0%	0	36%	0.364	C	S	.	.	H	α-helix	trans	-68	-44.3	175.7	176.4	-135.9	0	0	0	113.6	C58 G63 G64 M67 G273 I274 K275 V341 F345 F348	C58-Y277 HydrophobicContact CB-CD2 4.22Å; C58-Y277 HydrophobicContact CB-CE2 3.77Å; C58-Y277 WeakPolarHBondContact SG-CE2 3.13Å; G63-Y277 CarbonylContact C-O 3.59Å; G63-Y277 VanDerWaalsContact C-O 3.29Å; G63-Y277 WeakPolarHBondContact CA-O 3.4Å; G64-Y277 PolarHBondContact N-O 3.47Å; G64-Y277 VanDerWaalsContact N-O 3.16Å; M67-Y277 HydrophobicContact CE-CE1 4.48Å; M67-Y277 HydrophobicContact CE-CE2 3.74Å; M67-Y277 WeakPolarHBondContact CE-OH 3.19Å; G273-Y277 PolarHBondContact O-N 3.26Å; I274-Y277 WeakPolarHBondContact O-CB 3.2Å; I274-Y277 PolarHBondContact O-N 2.81Å; K275-Y277 PolarHBondContact O-N 3.36Å; Y277-V341 WeakPolarHBondContact OH-CA 3.21Å; Y277-V341 PolarHBondContact OH-O 2.98Å; Y277-F345 HydrophobicContact CD1-CD1 4.49Å; Y277-F345 HydrophobicContact CE1-CD1 4.48Å; Y277-F345 AromaticContact CE1-CD2 3.98Å; Y277-F345 HydrophobicContact CE1-CD2 3.98Å; Y277-F345 HydrophobicContact CE1-CE2 4.09Å; Y277-F345 HydrophobicContact CE1-CG 4.18Å; Y277-F345 HydrophobicContact CE1-CZ 4.41Å; Y277-F348 HydrophobicContact CD1-CD2 4.32Å; Y277-F348 AromaticContact CD2-CD2 3.58Å; Y277-F348 HydrophobicContact CD2-CD2 3.58Å; Y277-F348 AromaticContact CD2-CE2 3.6Å; Y277-F348 HydrophobicContact CD2-CE2 3.6Å; Y277-F348 HydrophobicContact CD2-CG 4.49Å; Y277-F348 HydrophobicContact CE2-CD2 4.32Å; Y277-F348 HydrophobicContact CE2-CE2 4.31Å; Y277-F348 HydrophobicContact CG-CB 4.44Å; Y277-F348 AromaticContact CG-CD2 3.58Å; Y277-F348 HydrophobicContact CG-CD2 3.58Å; Y277-F348 HydrophobicContact CG-CE2 4.06Å; Y277-F348 HydrophobicContact CG-CG 4.12Å
278	L	91.2	Very high	90.8	Very high	71 Å²	71	74.2 Å²	74.2	37%	0.372	38%	0.375	S	S	.	.	H	α-helix	trans	-95.7	-19.9	-170	-67.4	-178.2	0	0	0	115.1	G64 I274 K275 P280 F345	G64-L278 WeakPolarHBondContact CA-O 3.49Å; G64-L278 PolarHBondContact N-O 3.21Å; I274-L278 HydrophobicContact CG2-CD1 4.04Å; I274-L278 PolarHBondContact O-N 3.23Å; K275-L278 PolarHBondContact O-N 2.69Å; L278-P280 WeakPolarHBondContact O-CD 3.43Å; L278-P280 VanDerWaalsContact O-N 3.1Å; L278-F345 HydrophobicContact CD1-CE1 3.72Å; L278-F345 HydrophobicContact CD1-CZ 3.82Å; L278-F345 HydrophobicContact CD2-CE1 4.49Å; L278-F345 HydrophobicContact CD2-CZ 4.04Å; L278-F345 HydrophobicContact CG-CE1 4.33Å; L278-F345 HydrophobicContact CG-CZ 4.34Å
279	T	91.8	Very high	90.4	Very high	81 Å²	81	71.6 Å²	71.6	50%	0.497	36%	0.358	S	S	.	.			trans	-61.1	115.2	-177.9	-67.1	0	0	0	0	110.2	K275	K275-T279 WeakPolarHBondContact O-CB 3.31Å; K275-T279 PolarHBondContact O-N 2.9Å; K275-T279 PolarHBondContact O-OG1 3.33Å
280	P	92.9	Very high	90.3	Very high	59 Å²	59	70.8 Å²	70.8	38%	0.383	35%	0.35	S	S	.	.			trans	-81.5	127.3	-172.4	31.1	-33	0	0	0	111.5	A65 L278 W282	A65-P280 HydrophobicContact CB-CB 3.99Å; L278-P280 WeakPolarHBondContact O-CD 3.43Å; L278-P280 VanDerWaalsContact O-N 3.1Å; P280-W282 HydrophobicContact CB-CZ2 4.04Å; P280-W282 HydrophobicContact CG-CZ2 4.33Å
281	Q	92.3	Very high	90.1	Very high	98 Å²	98	73.9 Å²	73.9	46%	0.458	36%	0.36	S	S	.	.			trans	-104.5	83.4	171.4	-59.6	-179.4	3.4	0	0	110.2	G62 Q283 K284	G62-Q281 PolarHBondContact O-N 2.87Å; Q281-Q283 PolarHBondContact O-N 3.32Å; Q281-K284 HydrophobicContact CB-CG 4.13Å; Q281-K284 WeakPolarHBondContact O-CB 3.34Å; Q281-K284 PolarHBondContact O-N 2.9Å
282	W	91.7	Very high	89.6	Confident	157 Å²	157	68.7 Å²	68.7	60%	0.595	34%	0.336	S	S	*	.	H	α-helix	trans	-56.8	-28.3	-173.7	-62.4	109.4	0	0	0	114.7	A65 L68 P280 K284 V285	A65-W282 HydrophobicContact CB-CD2 4.48Å; A65-W282 HydrophobicContact CB-CE3 4.17Å; A65-W282 HydrophobicContact CB-CZ3 4.47Å; L68-W282 HydrophobicContact CD2-CZ3 4.2Å; P280-W282 HydrophobicContact CB-CZ2 4.04Å; P280-W282 HydrophobicContact CG-CZ2 4.33Å; W282-K284 PolarHBondContact O-N 3.43Å; W282-V285 PolarHBondContact O-N 3.24Å; W282-V285 VanDerWaalsContact O-N 3.15Å
283	Q	92.2	Very high	89.3	Confident	157 Å²	157	66.3 Å²	66.3	73%	0.734	32%	0.323	S	S	*	.	H	α-helix	trans	-61.3	-29.6	177	-61	-59.7	-18.5	0	0	112.8	Q281 V285 L286	Q281-Q283 PolarHBondContact O-N 3.32Å; Q283-V285 VanDerWaalsContact C-N 3.33Å; Q283-V285 PolarHBondContact O-N 3.03Å; Q283-L286 PolarHBondContact O-N 3.23Å
284	K	88.1	Confident	89.2	Confident	92 Å²	92	66.3 Å²	66.3	40%	0.4	32%	0.323	S	S	.	.	H	α-helix	trans	-69.7	-29.5	178.3	-68.7	-74.3	-174.2	169.9	0	112.4	Q281 W282 L286 D287 V290	Q281-K284 HydrophobicContact CB-CG 4.13Å; Q281-K284 WeakPolarHBondContact O-CB 3.34Å; Q281-K284 PolarHBondContact O-N 2.9Å; W282-K284 PolarHBondContact O-N 3.43Å; K284-L286 PolarHBondContact O-N 2.99Å; K284-D287 WeakPolarHBondContact O-CB 3.42Å; K284-D287 PolarHBondContact O-N 2.83Å; K284-V290 HydrophobicContact CB-CG2 4.33Å; K284-V290 WeakPolarHBondContact O-CG2 3.43Å
285	V	89.6	Confident	88.9	Confident	18 Å²	18	64.7 Å²	64.7	11%	0.109	32%	0.315	C	S	.	.	H	α-helix	trans	-67.7	-20.9	-179.5	-178.5	0	0	0	0	112.1	A65 W282 Q283 D287 W291	A65-V285 HydrophobicContact CB-CG2 3.69Å; A65-V285 WeakPolarHBondContact O-CG2 3.38Å; W282-V285 PolarHBondContact O-N 3.24Å; W282-V285 VanDerWaalsContact O-N 3.15Å; Q283-V285 VanDerWaalsContact C-N 3.33Å; Q283-V285 PolarHBondContact O-N 3.03Å; V285-D287 PolarHBondContact O-N 3.26Å; V285-W291 HydrophobicContact CG1-CZ2 3.99Å; V285-W291 PolarHBondContact O-NE1 3.43Å
286	L	88.8	Confident	88.5	Confident	140 Å²	140	60.1 Å²	60.1	73%	0.733	30%	0.299	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.2	-19.6	173.7	-60.3	175.3	0	0	0	112.5	Q283 K284 A288	Q283-L286 PolarHBondContact O-N 3.23Å; K284-L286 PolarHBondContact O-N 2.99Å; L286-A288 PolarHBondContact O-N 3.13Å
287	D	86.8	Confident	88.5	Confident	73 Å²	73	56.3 Å²	56.3	39%	0.39	28%	0.283	S	S	.	.	S	Bend	trans	-77.9	120.1	174.4	-173.4	-7.6	0	0	0	109.6	K284 V285 K289 V290	K284-D287 WeakPolarHBondContact O-CB 3.42Å; K284-D287 PolarHBondContact O-N 2.83Å; V285-D287 PolarHBondContact O-N 3.26Å; D287-K289 PolarHBondContact O-N 3.01Å; D287-K289 VanDerWaalsContact OD1-CB 3.28Å; D287-K289 WeakPolarHBondContact OD1-CB 3.24Å; D287-K289 PolarHBondContact OD1-N 3.07Å; D287-V290 HydrophobicContact CB-CG2 4.29Å; D287-V290 WeakPolarHBondContact O-CB 3.19Å; D287-V290 PolarHBondContact O-N 3.49Å
288	A	83.6	Confident	88.4	Confident	36 Å²	36	56.3 Å²	56.3	30%	0.298	28%	0.284	S	S	.	.	H	α-helix	trans	-57.3	-24.1	176.3	0	0	0	0	0	112.5	L286 V290 W291 G292 F523	L286-A288 PolarHBondContact O-N 3.13Å; A288-V290 PolarHBondContact O-N 3.02Å; A288-W291 PolarHBondContact O-N 3.42Å; A288-W291 VanDerWaalsContact O-N 3.15Å; A288-G292 PolarHBondContact O-N 3.47Å; A288-G292 VanDerWaalsContact O-N 3.11Å; A288-F523 HydrophobicContact CB-CD2 4.16Å; A288-F523 HydrophobicContact CB-CE2 3.26Å; A288-F523 HydrophobicContact CB-CZ 3.52Å; A288-F523 WeakPolarHBondContact O-CE1 3.42Å; A288-F523 WeakPolarHBondContact O-CZ 3.42Å
289	K	83.8	Confident	88.2	Confident	63 Å²	63	53.3 Å²	53.3	27%	0.274	27%	0.267	S	S	.	.	H	α-helix	trans	-60.1	-37.7	176.8	-171.8	178	172.8	-173	0	112	R60 D287 W291 G292 D293 F523	R60-K289 VanDerWaalsContact NH2-CE 3.32Å; D287-K289 PolarHBondContact O-N 3.01Å; D287-K289 VanDerWaalsContact OD1-CB 3.28Å; D287-K289 WeakPolarHBondContact OD1-CB 3.24Å; D287-K289 PolarHBondContact OD1-N 3.07Å; K289-W291 VanDerWaalsContact C-N 3.28Å; K289-W291 PolarHBondContact O-N 3.07Å; K289-G292 PolarHBondContact O-N 2.93Å; K289-D293 PolarHBondContact O-N 2.91Å; K289-F523 HydrophobicContact CB-CZ 4.32Å; K289-F523 VanDerWaalsContact N-CZ 3.27Å
290	V	88.8	Confident	87.8	Confident	1 Å²	1	50.6 Å²	50.6	1%	0.006	25%	0.248	C	C	.	.	H	α-helix	trans	-62.1	-38.4	179	170.7	0	0	0	0	111.2	N61 F66 P69 K284 D287 A288 A294	N61-V290 HydrophobicContact CB-CB 4.42Å; N61-V290 HydrophobicContact CB-CG1 4.07Å; N61-V290 HydrophobicContact CB-CG2 3.86Å; F66-V290 HydrophobicContact CD2-CG1 3.92Å; P69-V290 HydrophobicContact CG-CG1 3.88Å; K284-V290 HydrophobicContact CB-CG2 4.33Å; K284-V290 WeakPolarHBondContact O-CG2 3.43Å; D287-V290 HydrophobicContact CB-CG2 4.29Å; D287-V290 WeakPolarHBondContact O-CB 3.19Å; D287-V290 PolarHBondContact O-N 3.49Å; A288-V290 PolarHBondContact O-N 3.02Å; V290-A294 VanDerWaalsContact O-CB 3.29Å; V290-A294 WeakPolarHBondContact O-CB 3.24Å; V290-A294 PolarHBondContact O-N 3.42Å
291	W	87.6	Confident	87.7	Confident	67 Å²	67	48.1 Å²	48.1	25%	0.254	23%	0.233	S	C	.	.	H	α-helix	trans	-71.5	-38.2	176.4	-66.4	85	0	0	0	112.5	P69 I72 M73 V285 A288 K289 A294 A295	P69-W291 HydrophobicContact CB-CD2 3.63Å; P69-W291 HydrophobicContact CB-CE3 3.48Å; P69-W291 VanDerWaalsContact CB-CE3 3.48Å; P69-W291 HydrophobicContact CB-CG 4.27Å; P69-W291 HydrophobicContact CB-CH2 4.06Å; P69-W291 HydrophobicContact CB-CZ2 4.16Å; P69-W291 HydrophobicContact CB-CZ3 3.72Å; I72-W291 HydrophobicContact CB-CZ3 4.19Å; I72-W291 HydrophobicContact CD1-CH2 3.72Å; I72-W291 HydrophobicContact CD1-CZ3 4.05Å; I72-W291 HydrophobicContact CG2-CZ3 4Å; M73-W291 HydrophobicContact CE-CB 4.48Å; M73-W291 HydrophobicContact CE-CE3 3.71Å; M73-W291 HydrophobicContact CE-CZ3 4.4Å; V285-W291 HydrophobicContact CG1-CZ2 3.99Å; V285-W291 PolarHBondContact O-NE1 3.43Å; A288-W291 PolarHBondContact O-N 3.42Å; A288-W291 VanDerWaalsContact O-N 3.15Å; K289-W291 VanDerWaalsContact C-N 3.28Å; K289-W291 PolarHBondContact O-N 3.07Å; W291-A294 PolarHBondContact O-N 3.29Å; W291-A295 WeakPolarHBondContact O-CB 3.43Å; W291-A295 PolarHBondContact O-N 3.42Å
292	G	83.1	Confident	87.6	Confident	7 Å²	7	43.5 Å²	43.5	7%	0.072	21%	0.211	C	C	.	.	H	α-helix	trans	-63.4	-45.2	173.8	0	0	0	0	0	112.8	A288 K289 A295 S296	A288-G292 PolarHBondContact O-N 3.47Å; A288-G292 VanDerWaalsContact O-N 3.11Å; K289-G292 PolarHBondContact O-N 2.93Å; G292-A295 PolarHBondContact O-N 3.37Å; G292-S296 VanDerWaalsContact O-CB 3.31Å; G292-S296 WeakPolarHBondContact O-CB 3.38Å; G292-S296 PolarHBondContact O-N 3.31Å; G292-S296 PolarHBondContact O-OG 3.32Å
293	D	85.8	Confident	87.5	Confident	31 Å²	31	36.1 Å²	36.1	17%	0.166	18%	0.184	C	C	.	.	H	α-helix	trans	-63.9	-41.9	175.7	-79	-4.4	0	0	0	110.9	L57 R60 N61 F66 K289 Q297	L57-D293 HydrophobicContact CD2-CB 4.34Å; R60-D293 IonicContact CZ-OD2 2.68Å; R60-D293 IonicContact NH2-OD2 3.08Å; R60-D293 PolarHBondContact NH2-OD2 2.97Å; N61-D293 VanDerWaalsContact ND2-CB 3.29Å; N61-D293 WeakPolarHBondContact ND2-CB 3.47Å; N61-D293 PolarHBondContact ND2-OD2 3.39Å; N61-D293 PolarHBondContact OD1-OD2 2.94Å; F66-D293 HydrophobicContact CE2-CB 4.41Å; K289-D293 PolarHBondContact O-N 2.91Å; D293-Q297 WeakPolarHBondContact O-CB 3.39Å; D293-Q297 PolarHBondContact O-N 3.1Å
294	A	90	Very high	87.3	Confident	0 Å²	0	28.7 Å²	28.7	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-61.8	-47.3	176.3	0	0	0	0	0	112.3	F66 P69 M73 V290 W291 Q297 I298	F66-A294 HydrophobicContact CD2-CB 4.49Å; F66-A294 HydrophobicContact CE2-CB 3.68Å; F66-A294 HydrophobicContact CZ-CB 3.93Å; P69-A294 HydrophobicContact CB-CB 4.04Å; P69-A294 HydrophobicContact CG-CB 4.44Å; M73-A294 HydrophobicContact CG-CB 4.5Å; V290-A294 VanDerWaalsContact O-CB 3.29Å; V290-A294 WeakPolarHBondContact O-CB 3.24Å; V290-A294 PolarHBondContact O-N 3.42Å; W291-A294 PolarHBondContact O-N 3.29Å; A294-Q297 PolarHBondContact O-N 3.21Å; A294-I298 WeakPolarHBondContact O-CG1 3.23Å; A294-I298 PolarHBondContact O-N 3.25Å; A294-I298 VanDerWaalsContact O-N 3.12Å
295	A	86.1	Confident	87.4	Confident	1 Å²	1	24.3 Å²	24.3	1%	0.008	13%	0.13	C	C	.	.	H	α-helix	trans	-65.2	-48	178.1	0	0	0	0	0	111.5	M73 W291 G292 Q297 I298 F299 I520	M73-A295 HydrophobicContact CE-CB 4.39Å; M73-A295 HydrophobicContact CG-CB 3.98Å; M73-A295 HydrophobicContact SD-CB 3.82Å; W291-A295 WeakPolarHBondContact O-CB 3.43Å; W291-A295 PolarHBondContact O-N 3.42Å; G292-A295 PolarHBondContact O-N 3.37Å; A295-Q297 PolarHBondContact O-N 3.29Å; A295-I298 WeakPolarHBondContact O-CB 3.48Å; A295-I298 PolarHBondContact O-N 3.4Å; A295-F299 VanDerWaalsContact O-CD2 3.26Å; A295-F299 WeakPolarHBondContact O-CD2 3.37Å; A295-F299 PolarHBondContact O-N 2.94Å; A295-I520 HydrophobicContact CB-CD1 3.28Å; A295-I520 HydrophobicContact CB-CG1 3.81Å
296	S	83.6	Confident	87.4	Confident	28 Å²	28	24.1 Å²	24.1	20%	0.196	13%	0.127	C	C	.	.	H	α-helix	trans	-55.3	-43.2	177.4	-59.4	0	0	0	0	111.1	G292 I298 F299 Y300	G292-S296 VanDerWaalsContact O-CB 3.31Å; G292-S296 WeakPolarHBondContact O-CB 3.38Å; G292-S296 PolarHBondContact O-N 3.31Å; G292-S296 PolarHBondContact O-OG 3.32Å; S296-I298 PolarHBondContact O-N 3Å; S296-F299 PolarHBondContact O-N 3.45Å; S296-Y300 WeakPolarHBondContact O-CB 3.3Å; S296-Y300 WeakPolarHBondContact O-CD2 3.38Å; S296-Y300 PolarHBondContact O-N 3.39Å
297	Q	88.9	Confident	87.6	Confident	2 Å²	2	17.4 Å²	17.4	1%	0.009	9%	0.092	C	C	.	.	H	α-helix	trans	-61.7	-40.4	175.9	-177.4	58.9	26.6	0	0	112.7	R53 F54 L57 Y70 D293 A294 A295 S301	R53-Q297 VanDerWaalsContact CD-OE1 3.23Å; F54-Q297 HydrophobicContact CD2-CG 4.12Å; L57-Q297 HydrophobicContact CD1-CB 3.75Å; L57-Q297 HydrophobicContact CD1-CG 3.98Å; L57-Q297 VanDerWaalsContact CD1-OE1 3.29Å; Y70-Q297 HydrophobicContact CD2-CG 4.45Å; Y70-Q297 HydrophobicContact CE2-CB 4.44Å; Y70-Q297 HydrophobicContact CE2-CG 3.89Å; D293-Q297 WeakPolarHBondContact O-CB 3.39Å; D293-Q297 PolarHBondContact O-N 3.1Å; A294-Q297 PolarHBondContact O-N 3.21Å; A295-Q297 PolarHBondContact O-N 3.29Å; Q297-S301 WeakPolarHBondContact O-CB 3.17Å; Q297-S301 PolarHBondContact O-N 3.05Å
298	I	90.7	Very high	87.8	Confident	1 Å²	1	14 Å²	14	1%	0.005	7%	0.074	C	C	.	.	H	α-helix	trans	-64.5	-44.8	176.2	-69.3	-67.9	0	0	0	111.3	Y70 M73 L74 A294 A295 S296 S301 L302	Y70-I298 HydrophobicContact CD2-CD1 3.64Å; Y70-I298 HydrophobicContact CD2-CG1 3.82Å; Y70-I298 HydrophobicContact CE1-CD1 4.23Å; Y70-I298 HydrophobicContact CE2-CD1 3.19Å; Y70-I298 HydrophobicContact CE2-CG1 3.74Å; Y70-I298 HydrophobicContact CG-CD1 4.31Å; M73-I298 HydrophobicContact CB-CG1 4.09Å; L74-I298 HydrophobicContact CB-CD1 3.76Å; L74-I298 HydrophobicContact CD1-CD1 4.06Å; L74-I298 HydrophobicContact CG-CD1 4.45Å; A294-I298 WeakPolarHBondContact O-CG1 3.23Å; A294-I298 PolarHBondContact O-N 3.25Å; A294-I298 VanDerWaalsContact O-N 3.12Å; A295-I298 WeakPolarHBondContact O-CB 3.48Å; A295-I298 PolarHBondContact O-N 3.4Å; S296-I298 PolarHBondContact O-N 3Å; I298-S301 PolarHBondContact O-N 2.84Å; I298-L302 HydrophobicContact CG2-CD1 3.88Å; I298-L302 WeakPolarHBondContact O-CB 3.31Å; I298-L302 PolarHBondContact O-N 3.44Å
299	F	85.7	Confident	88.2	Confident	7 Å²	7	12.3 Å²	12.3	3%	0.031	6%	0.06	C	C	.	.	H	α-helix	trans	-62.4	-47	177.6	-84.5	-81.5	0	0	0	112.2	L81 A295 S296 G303 C304 S473 I517 I520	L81-F299 HydrophobicContact CD1-CE1 3.46Å; L81-F299 VanDerWaalsContact CD1-CE1 3.46Å; L81-F299 HydrophobicContact CD1-CZ 3.39Å; A295-F299 VanDerWaalsContact O-CD2 3.26Å; A295-F299 WeakPolarHBondContact O-CD2 3.37Å; A295-F299 PolarHBondContact O-N 2.94Å; S296-F299 PolarHBondContact O-N 3.45Å; F299-G303 PolarHBondContact O-N 3.03Å; F299-G303 VanDerWaalsContact O-N 3.16Å; F299-C304 HydrophobicContact CD1-CB 4.01Å; F299-C304 HydrophobicContact CE1-CB 4.38Å; F299-C304 PolarHBondContact O-N 2.95Å; F299-S473 WeakPolarHBondContact CE1-OG 3.3Å; F299-I517 HydrophobicContact CE2-CG1 4.39Å; F299-I517 HydrophobicContact CZ-CD1 4.1Å; F299-I517 HydrophobicContact CZ-CG1 3.69Å; F299-I520 HydrophobicContact CE2-CD1 4.23Å
300	Y	84.6	Confident	88.7	Confident	24 Å²	24	9.3 Å²	9.3	9%	0.094	5%	0.047	C	C	.	.	H	α-helix	trans	-66.8	-40.5	178	-93.7	-80.5	0	0	0	112.7	S296 W306 D461 A465 S466	S296-Y300 WeakPolarHBondContact O-CB 3.3Å; S296-Y300 WeakPolarHBondContact O-CD2 3.38Å; S296-Y300 PolarHBondContact O-N 3.39Å; Y300-W306 HydrophobicContact CD1-CH2 4.44Å; Y300-W306 AromaticContact CD1-CZ2 3.81Å; Y300-W306 HydrophobicContact CD1-CZ2 3.81Å; Y300-W306 HydrophobicContact CE1-CZ2 4.36Å; Y300-D461 PolarHBondContact OH-O 2.85Å; Y300-A465 HydrophobicContact CE1-CB 3.87Å; Y300-A465 WeakPolarHBondContact OH-CB 3.45Å; Y300-S466 VanDerWaalsContact OH-CA 3.31Å; Y300-S466 WeakPolarHBondContact OH-CA 3.35Å; Y300-S466 PolarHBondContact OH-N 3.1Å; Y300-S466 PolarHBondContact OH-OG 2.96Å
301	S	90.4	Very high	88.9	Confident	8 Å²	8	9.2 Å²	9.2	6%	0.056	5%	0.047	C	C	.	.	H	α-helix	trans	-75.3	-40.4	-176.5	-177	0	0	0	0	112.1	A45 N50 Q297 I298 G303 N336	A45-S301 CarbonylContact C-O 3.55Å; A45-S301 WeakPolarHBondContact CA-O 3.46Å; N50-S301 PolarHBondContact ND2-OG 3.09Å; Q297-S301 WeakPolarHBondContact O-CB 3.17Å; Q297-S301 PolarHBondContact O-N 3.05Å; I298-S301 PolarHBondContact O-N 2.84Å; S301-G303 PolarHBondContact O-N 3.32Å; S301-N336 PolarHBondContact OG-ND2 3.35Å; S301-N336 PolarHBondContact OG-OD1 2.69Å; S301-N336 VanDerWaalsContact OG-OD1 3.07Å
302	L	90.6	Very high	89.2	Confident	0 Å²	0	6.1 Å²	6.1	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-77.9	-11.9	176.2	-68.8	175.8	0	0	0	113.1	L74 G78 F82 I298 C304 N336	L74-L302 HydrophobicContact CD1-CD1 4.09Å; G78-L302 VanDerWaalsContact CA-CD1 3.46Å; F82-L302 HydrophobicContact CD2-CB 4.04Å; F82-L302 HydrophobicContact CD2-CD2 4.12Å; F82-L302 HydrophobicContact CD2-CG 4.46Å; F82-L302 HydrophobicContact CE2-CB 4.46Å; F82-L302 HydrophobicContact CE2-CD2 4.31Å; I298-L302 HydrophobicContact CG2-CD1 3.88Å; I298-L302 WeakPolarHBondContact O-CB 3.31Å; I298-L302 PolarHBondContact O-N 3.44Å; L302-C304 VanDerWaalsContact C-N 3.25Å; L302-C304 VanDerWaalsContact CB-SG 3.56Å; L302-C304 PolarHBondContact O-N 3.15Å; L302-N336 HydrophobicContact CD2-CB 4.15Å; L302-N336 WeakPolarHBondContact CD2-ND2 3.48Å
303	G	88.1	Confident	89.5	Confident	2 Å²	2	5.8 Å²	5.8	2%	0.021	3%	0.031	C	C	.	.	T	Hydrogen-bonded Turn	trans	62.9	33.3	-175.5	0	0	0	0	0	112.6	Y44 F299 S301	Y44-G303 WeakPolarHBondContact OH-CA 3.31Å; Y44-G303 PolarHBondContact OH-O 2.84Å; F299-G303 PolarHBondContact O-N 3.03Å; F299-G303 VanDerWaalsContact O-N 3.16Å; S301-G303 PolarHBondContact O-N 3.32Å
304	C	89.1	Confident	89.8	Confident	1 Å²	1	4.4 Å²	4.4	1%	0.007	2%	0.024	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.4	140.7	179.5	-66.8	0	0	0	0	110.4	F299 L302 W306	F299-C304 HydrophobicContact CD1-CB 4.01Å; F299-C304 HydrophobicContact CE1-CB 4.38Å; F299-C304 PolarHBondContact O-N 2.95Å; L302-C304 VanDerWaalsContact C-N 3.25Å; L302-C304 VanDerWaalsContact CB-SG 3.56Å; L302-C304 PolarHBondContact O-N 3.15Å; C304-W306 VanDerWaalsContact C-N 3.27Å; C304-W306 PolarHBondContact O-N 3.47Å; C304-W306 PolarHBondContact O-NE1 3.11Å
305	A	89.6	Confident	89.8	Confident	0 Å²	0	4.6 Å²	4.6	0%	0	3%	0.025	C	C	.	.	T	Hydrogen-bonded Turn	trans	66.7	20.5	-178.7	0	0	0	0	0	114.7	E85 M113 L469 I472	E85-A305 WeakPolarHBondContact OE1-CA 3.26Å; E85-A305 PolarHBondContact OE1-N 3.23Å; E85-A305 PolarHBondContact OE2-N 2.9Å; M113-A305 HydrophobicContact CE-CB 4.46Å; M113-A305 WeakPolarHBondContact CG-O 3.44Å; A305-L469 HydrophobicContact CB-CD2 4.44Å; A305-L469 WeakPolarHBondContact O-CD2 3.19Å; A305-I472 HydrophobicContact CB-CG2 4.04Å
306	W	90.9	Very high	89.9	Confident	14 Å²	14	4.8 Å²	4.8	5%	0.053	3%	0.025	C	C	.	.	S	Bend	trans	-93	-13.6	174.2	-59.2	16.3	0	0	0	110.9	Y44 S117 I120 Y300 C304 G308 T405 L409 L469	Y44-W306 HydrophobicContact CE2-CE3 4.05Å; Y44-W306 HydrophobicContact CE2-CZ3 4.47Å; Y44-W306 VanDerWaalsContact OH-CB 3.31Å; Y44-W306 WeakPolarHBondContact OH-CB 3.49Å; Y44-W306 VanDerWaalsContact OH-CE3 3.27Å; S117-W306 PolarHBondContact OG-O 2.87Å; I120-W306 HydrophobicContact CD1-CD2 3.81Å; I120-W306 HydrophobicContact CD1-CE3 3.9Å; I120-W306 HydrophobicContact CD1-CH2 3.83Å; I120-W306 HydrophobicContact CD1-CZ2 3.75Å; I120-W306 HydrophobicContact CD1-CZ3 3.91Å; I120-W306 HydrophobicContact CG2-CH2 4.22Å; I120-W306 HydrophobicContact CG2-CZ3 3.99Å; Y300-W306 HydrophobicContact CD1-CH2 4.44Å; Y300-W306 AromaticContact CD1-CZ2 3.81Å; Y300-W306 HydrophobicContact CD1-CZ2 3.81Å; Y300-W306 HydrophobicContact CE1-CZ2 4.36Å; C304-W306 VanDerWaalsContact C-N 3.27Å; C304-W306 PolarHBondContact O-N 3.47Å; C304-W306 PolarHBondContact O-NE1 3.11Å; W306-G308 PolarHBondContact O-N 3.44Å; W306-T405 HydrophobicContact CZ3-CG2 4.34Å; W306-L409 HydrophobicContact CE3-CD2 3.76Å; W306-L409 HydrophobicContact CZ3-CD2 4.21Å; W306-L469 HydrophobicContact CG-CD2 4.2Å; W306-L469 HydrophobicContact CZ2-CD1 4.36Å
307	G	91.1	Very high	90	Very high	0 Å²	0	6.8 Å²	6.8	0%	0	3%	0.031	C	C	.	.	S	Bend	trans	80.7	-7.2	-172.6	0	0	0	0	0	114.3	T311	G307-T311 WeakPolarHBondContact O-CB 3.32Å; G307-T311 PolarHBondContact O-N 2.84Å; G307-T311 PolarHBondContact O-OG1 3.26Å
308	G	91.8	Very high	89.6	Confident	0 Å²	0	6.8 Å²	6.8	0%	0	3%	0.031	C	C	.	.	H	α-helix	trans	-57.2	-51.9	172.7	0	0	0	0	0	113.1	W306 I310 T311 M312 C408 T412	W306-G308 PolarHBondContact O-N 3.44Å; G308-I310 PolarHBondContact O-N 2.96Å; G308-T311 PolarHBondContact O-N 3.23Å; G308-M312 WeakPolarHBondContact O-CG 3.14Å; G308-M312 PolarHBondContact O-N 3.39Å; G308-C408 VanDerWaalsContact CA-SG 3.55Å; G308-T412 VanDerWaalsContact CA-OG1 3.32Å; G308-T412 WeakPolarHBondContact CA-OG1 3.12Å
309	L	92.6	Very high	88.7	Confident	1 Å²	1	11.5 Å²	11.5	1%	0.005	5%	0.053	C	C	.	.	H	α-helix	trans	-63.1	-43.7	-179.9	-61.7	176.6	0	0	0	112.3	Y44 F82 E85 L86 T311 M312 A313	Y44-L309 HydrophobicContact CD1-CD2 3.59Å; Y44-L309 HydrophobicContact CD1-CG 4.31Å; Y44-L309 HydrophobicContact CE1-CD2 3.58Å; Y44-L309 HydrophobicContact CE1-CG 3.78Å; F82-L309 HydrophobicContact CD2-CD1 3.33Å; F82-L309 HydrophobicContact CD2-CD2 4.15Å; F82-L309 HydrophobicContact CD2-CG 4.38Å; F82-L309 HydrophobicContact CE1-CD2 4.38Å; F82-L309 HydrophobicContact CE2-CD1 3.46Å; F82-L309 VanDerWaalsContact CE2-CD1 3.46Å; F82-L309 HydrophobicContact CE2-CD2 3.36Å; F82-L309 HydrophobicContact CE2-CG 4.04Å; F82-L309 HydrophobicContact CG-CD1 4Å; F82-L309 HydrophobicContact CZ-CD1 4.19Å; F82-L309 HydrophobicContact CZ-CD2 3.48Å; F82-L309 VanDerWaalsContact CZ-CD2 3.48Å; F82-L309 HydrophobicContact CZ-CG 4.48Å; E85-L309 HydrophobicContact CB-CB 4Å; E85-L309 HydrophobicContact CB-CD1 4.4Å; L86-L309 HydrophobicContact CD2-CB 4.16Å; L86-L309 HydrophobicContact CD2-CD2 4.48Å; L309-T311 VanDerWaalsContact C-N 3.28Å; L309-T311 PolarHBondContact O-N 3.45Å; L309-M312 PolarHBondContact O-N 3.37Å; L309-A313 VanDerWaalsContact O-CB 3.24Å; L309-A313 WeakPolarHBondContact O-CB 3.28Å; L309-A313 PolarHBondContact O-N 3.36Å
310	I	94.1	Very high	87.6	Confident	0 Å²	0	12.2 Å²	12.2	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-57	-46.6	175.4	-61.8	175.5	0	0	0	109.8	E85 F88 V99 M113 G308 A313 S314	E85-I310 HydrophobicContact CB-CG1 3.92Å; E85-I310 HydrophobicContact CG-CD1 4.29Å; E85-I310 HydrophobicContact CG-CG1 4.03Å; F88-I310 HydrophobicContact CD1-CD1 3.99Å; F88-I310 HydrophobicContact CD1-CG1 4.5Å; F88-I310 HydrophobicContact CE1-CD1 4.4Å; V99-I310 HydrophobicContact CB-CG2 4.4Å; V99-I310 HydrophobicContact CG1-CG2 3.63Å; V99-I310 HydrophobicContact CG2-CD1 4.39Å; V99-I310 HydrophobicContact CG2-CG2 3.93Å; M113-I310 HydrophobicContact CE-CD1 4.24Å; M113-I310 HydrophobicContact SD-CD1 4.09Å; G308-I310 PolarHBondContact O-N 2.96Å; I310-A313 PolarHBondContact O-N 3.18Å; I310-S314 WeakPolarHBondContact O-CB 3.41Å; I310-S314 PolarHBondContact O-N 3.29Å
311	T	93.5	Very high	86.1	Confident	0 Å²	0	17.1 Å²	17.1	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-64	-48.2	179	-59	0	0	0	0	111.5	G307 G308 L309 A313 S314 Y315 E411 T415	G307-T311 WeakPolarHBondContact O-CB 3.32Å; G307-T311 PolarHBondContact O-N 2.84Å; G307-T311 PolarHBondContact O-OG1 3.26Å; G308-T311 PolarHBondContact O-N 3.23Å; L309-T311 VanDerWaalsContact C-N 3.28Å; L309-T311 PolarHBondContact O-N 3.45Å; T311-A313 VanDerWaalsContact C-N 3.31Å; T311-A313 PolarHBondContact O-N 3.17Å; T311-S314 WeakPolarHBondContact O-CB 3.44Å; T311-S314 PolarHBondContact O-N 3Å; T311-S314 VanDerWaalsContact O-N 3.17Å; T311-S314 PolarHBondContact O-OG 3.38Å; T311-Y315 HydrophobicContact CG2-CE2 4.04Å; T311-Y315 WeakPolarHBondContact O-CD2 3.44Å; T311-E411 HydrophobicContact CG2-CG 4.48Å; T311-T415 HydrophobicContact CG2-CG2 3.97Å
312	M	92	Very high	83.9	Confident	2 Å²	2	19.2 Å²	19.2	1%	0.01	10%	0.099	C	C	.	.	H	α-helix	trans	-63.9	-38.2	179.7	-66.6	-55.4	159.1	0	0	112.7	W31 F37 T40 G308 L309 S314 Y315 C408 E411	W31-M312 HydrophobicContact CH2-SD 3.78Å; W31-M312 HydrophobicContact CZ2-CB 4.37Å; W31-M312 HydrophobicContact CZ2-SD 3.56Å; W31-M312 VanDerWaalsContact CZ2-SD 3.56Å; W31-M312 PolarHBondContact NE1-O 2.93Å; F37-M312 HydrophobicContact CE2-CB 4.34Å; T40-M312 HydrophobicContact CG2-CE 4.39Å; T40-M312 HydrophobicContact CG2-CG 4.47Å; T40-M312 HydrophobicContact CG2-SD 3.87Å; G308-M312 WeakPolarHBondContact O-CG 3.14Å; G308-M312 PolarHBondContact O-N 3.39Å; L309-M312 PolarHBondContact O-N 3.37Å; M312-S314 VanDerWaalsContact C-N 3.31Å; M312-S314 PolarHBondContact O-N 3.17Å; M312-Y315 PolarHBondContact O-N 3.17Å; M312-C408 HydrophobicContact CE-CB 3.66Å; M312-C408 WeakPolarHBondContact CE-SG 3.45Å; M312-E411 HydrophobicContact CE-CB 3.92Å; M312-E411 HydrophobicContact CE-CG 4.08Å
313	A	91.1	Very high	82	Confident	0 Å²	0	26.5 Å²	26.5	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-69	-29.5	176.6	0	0	0	0	0	113.1	L86 Q90 L309 I310 T311 Y315 N316	L86-A313 HydrophobicContact CB-CB 4.34Å; L86-A313 HydrophobicContact CD2-CB 3.81Å; L86-A313 WeakPolarHBondContact O-CB 3.42Å; Q90-A313 WeakPolarHBondContact CA-O 3.33Å; Q90-A313 HydrophobicContact CB-CB 4.23Å; L309-A313 VanDerWaalsContact O-CB 3.24Å; L309-A313 WeakPolarHBondContact O-CB 3.28Å; L309-A313 PolarHBondContact O-N 3.36Å; I310-A313 PolarHBondContact O-N 3.18Å; T311-A313 VanDerWaalsContact C-N 3.31Å; T311-A313 PolarHBondContact O-N 3.17Å; A313-Y315 PolarHBondContact O-N 2.99Å; A313-Y315 VanDerWaalsContact O-N 3.17Å; A313-N316 VanDerWaalsContact O-CB 3.24Å; A313-N316 WeakPolarHBondContact O-CB 3.39Å; A313-N316 PolarHBondContact O-N 3.06Å
314	S	91.7	Very high	80.7	Confident	1 Å²	1	31.1 Å²	31.1	1%	0.007	15%	0.147	C	C	.	.	H	α-helix	trans	-64	-19.7	-179.9	77.1	0	0	0	0	114.3	R28 L94 I310 T311 M312	R28-S314 WeakPolarHBondContact CD-O 3.49Å; R28-S314 PolarHBondContact NE-O 3.11Å; R28-S314 VanDerWaalsContact NE-O 3.14Å; R28-S314 PolarHBondContact NE-OG 3.36Å; R28-S314 VanDerWaalsContact NE-OG 3.07Å; R28-S314 VanDerWaalsContact NH2-CB 3.31Å; R28-S314 PolarHBondContact NH2-OG 2.93Å; L94-S314 VanDerWaalsContact O-CB 3.29Å; L94-S314 WeakPolarHBondContact O-CB 3.43Å; I310-S314 WeakPolarHBondContact O-CB 3.41Å; I310-S314 PolarHBondContact O-N 3.29Å; T311-S314 WeakPolarHBondContact O-CB 3.44Å; T311-S314 PolarHBondContact O-N 3Å; T311-S314 VanDerWaalsContact O-N 3.17Å; T311-S314 PolarHBondContact O-OG 3.38Å; M312-S314 VanDerWaalsContact C-N 3.31Å; M312-S314 PolarHBondContact O-N 3.17Å
315	Y	89.6	Confident	79.3	Confident	5 Å²	5	31.1 Å²	31.1	2%	0.02	15%	0.147	C	C	.	.	T	Hydrogen-bonded Turn	trans	-89.1	-6.1	175.6	-68	-73.3	0	0	0	112.9	R28 G29 N30 W31 V239 T311 M312 A313 E411 T415 K430	R28-Y315 HydrophobicContact CG-CD1 3.82Å; R28-Y315 HydrophobicContact CG-CE1 3.58Å; R28-Y315 WeakPolarHBondContact O-CE1 3.47Å; G29-Y315 WeakPolarHBondContact O-CD1 3.48Å; N30-Y315 VanDerWaalsContact CA-O 3.32Å; N30-Y315 WeakPolarHBondContact CA-O 3.34Å; N30-Y315 PolarHBondContact ND2-O 3.01Å; W31-Y315 PolarHBondContact N-O 3.4Å; V239-Y315 HydrophobicContact CG1-CD1 4.29Å; V239-Y315 HydrophobicContact CG1-CD2 3.56Å; V239-Y315 HydrophobicContact CG1-CE1 4.39Å; V239-Y315 HydrophobicContact CG1-CE2 3.66Å; V239-Y315 HydrophobicContact CG1-CG 3.91Å; V239-Y315 HydrophobicContact CG2-CD1 3.89Å; V239-Y315 HydrophobicContact CG2-CE1 4.19Å; V239-Y315 HydrophobicContact CG2-CG 4.12Å; T311-Y315 HydrophobicContact CG2-CE2 4.04Å; T311-Y315 WeakPolarHBondContact O-CD2 3.44Å; M312-Y315 PolarHBondContact O-N 3.17Å; A313-Y315 PolarHBondContact O-N 2.99Å; A313-Y315 VanDerWaalsContact O-N 3.17Å; Y315-E411 HydrophobicContact CE2-CG 4.47Å; Y315-E411 PolarHBondContact OH-OE1 3.17Å; Y315-T415 PolarHBondContact OH-OG1 3.49Å; Y315-K430 PolarHBondContact OH-NZ 3.19Å; Y315-K430 VanDerWaalsContact OH-NZ 3.11Å
316	N	89.1	Confident	78.3	Confident	4 Å²	4	32.8 Å²	32.8	2%	0.021	16%	0.155	C	C	.	.	S	Bend	trans	-69.8	154.8	172.7	-70.2	-21.7	0	0	0	110.8	W31 F37 Q90 A313	W31-N316 PolarHBondContact NE1-OD1 3.22Å; F37-N316 VanDerWaalsContact CD2-OD1 3.29Å; F37-N316 WeakPolarHBondContact CD2-OD1 3.24Å; F37-N316 VanDerWaalsContact CE2-ND2 3.35Å; F37-N316 WeakPolarHBondContact CE2-ND2 3.37Å; F37-N316 WeakPolarHBondContact CG-OD1 3.41Å; F37-N316 WeakPolarHBondContact CZ-ND2 3.4Å; Q90-N316 HydrophobicContact CG-CB 3.93Å; A313-N316 VanDerWaalsContact O-CB 3.24Å; A313-N316 WeakPolarHBondContact O-CB 3.39Å; A313-N316 PolarHBondContact O-N 3.06Å
317	K	85.5	Confident	77.6	Confident	70 Å²	70	37.9 Å²	37.9	30%	0.304	17%	0.174	S	C	.	.			trans	-67.2	148.8	170.3	-64.1	-170.1	179.3	-163.5	0	110.5	E24 Q90 N320	E24-K317 WeakPolarHBondContact OE2-CA 2.95Å; E24-K317 WeakPolarHBondContact OE2-CB 3.47Å; Q90-K317 PolarHBondContact NE2-O 2.64Å; K317-N320 PolarHBondContact O-N 3.28Å
318	F	79.1	Confident	77.1	Confident	2 Å²	2	38.1 Å²	38.1	1%	0.009	18%	0.175	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.1	-54.2	-176.1	-174.1	-100.6	0	0	0	110.8	E24 Q90 F91 N320 M495 M496 P589 H594	E24-F318 PolarHBondContact OE2-N 3.21Å; Q90-F318 PolarHBondContact NE2-O 3.44Å; F91-F318 AromaticContact CD2-CE2 3.93Å; F91-F318 HydrophobicContact CD2-CE2 3.93Å; F91-F318 HydrophobicContact CD2-CZ 4.18Å; F91-F318 HydrophobicContact CE2-CE2 4.3Å; F91-F318 HydrophobicContact CE2-CZ 4.23Å; F91-F318 WeakPolarHBondContact O-CE2 3.44Å; F318-N320 VanDerWaalsContact C-N 3.32Å; F318-N320 PolarHBondContact O-N 2.81Å; F318-M495 HydrophobicContact CZ-CG 4.35Å; F318-M496 WeakPolarHBondContact O-CG 3.4Å; F318-P589 HydrophobicContact CD2-CB 4.15Å; F318-P589 HydrophobicContact CE2-CB 3.6Å; F318-P589 HydrophobicContact CE2-CG 3.56Å; F318-P589 HydrophobicContact CZ-CB 3.94Å; F318-P589 HydrophobicContact CZ-CG 3.53Å; F318-H594 WeakPolarHBondContact CB-CD2 3.39Å; F318-H594 HydrophobicContact CD1-CB 3.61Å; F318-H594 AromaticContact CD1-CD2 3.73Å; F318-H594 AromaticContact CD1-CG 3.28Å; F318-H594 AromaticContact CD1-ND1 3.48Å; F318-H594 WeakPolarHBondContact CD1-ND1 3.34Å; F318-H594 HydrophobicContact CD2-CB 4.34Å; F318-H594 HydrophobicContact CE1-CB 3.68Å; F318-H594 AromaticContact CE1-CG 3.88Å; F318-H594 HydrophobicContact CE2-CB 4.41Å; F318-H594 HydrophobicContact CG-CB 3.96Å; F318-H594 AromaticContact CG-CD2 3.53Å; F318-H594 AromaticContact CG-CG 3.57Å; F318-H594 HydrophobicContact CZ-CB 4.1Å
319	H	71.8	Confident	76.6	Confident	101 Å²	101	38.1 Å²	38.1	47%	0.468	18%	0.175	S	C	.	.	T	Hydrogen-bonded Turn	trans	-91.7	64.3	168.6	-65.8	-26.1	0	0	0	110.8	N321 M495	H319-N321 PolarHBondContact O-N 3.38Å; H319-M495 PolarHBondContact CE1-O 2.69Å
320	N	62.9	Low	76.3	Confident	21 Å²	21	40.5 Å²	40.5	11%	0.112	19%	0.187	C	C	.	.	S	Bend	trans	-71	112.1	162.8	-163.4	21.8	0	0	0	107.4	Q34 K317 F318 C322	Q34-N320 PolarHBondContact NE2-ND2 2.9Å; Q34-N320 PolarHBondContact OE1-ND2 3.48Å; Q34-N320 PolarHBondContact OE1-OD1 3.33Å; K317-N320 PolarHBondContact O-N 3.28Å; F318-N320 VanDerWaalsContact C-N 3.32Å; F318-N320 PolarHBondContact O-N 2.81Å; N320-C322 PolarHBondContact O-N 2.89Å
321	N	53.5	Low	76.1	Confident	128 Å²	128	43.6 Å²	43.6	68%	0.684	20%	0.204	S	C	*	.			trans	-19.7	103.4	-169.9	-81.9	9.6	0	0	0	113.8	H319 F323 R324	H319-N321 PolarHBondContact O-N 3.38Å; N321-F323 PolarHBondContact O-N 3.04Å; N321-R324 WeakPolarHBondContact O-CB 3.31Å; N321-R324 PolarHBondContact O-N 3.3Å
322	C	44.9	Very low	76	Confident	52 Å²	52	43.6 Å²	43.6	35%	0.351	20%	0.204	S	C	.	.	T	Hydrogen-bonded Turn	trans	-8.7	-46.7	179.1	-71.3	0	0	0	0	118.8	N320 L497 F499	N320-C322 PolarHBondContact O-N 2.89Å; C322-L497 WeakPolarHBondContact CA-O 3.39Å; C322-L497 WeakPolarHBondContact CB-O 3.19Å; C322-L497 WeakPolarHBondContact O-CD2 3.35Å; C322-L497 PolarHBondContact SG-O 3.26Å; C322-F499 HydrophobicContact CB-CD1 4.39Å; C322-F499 HydrophobicContact CB-CE1 4.3Å; C322-F499 WeakPolarHBondContact O-CE1 3.28Å; C322-F499 WeakPolarHBondContact O-CZ 3.33Å
323	F	50.1	Low	76	Confident	152 Å²	152	43.5 Å²	43.5	67%	0.667	20%	0.203	S	C	*	.	T	Hydrogen-bonded Turn	trans	-83.6	-15	-174.9	-127.8	-98.4	0	0	0	115.2	N321 F499	N321-F323 PolarHBondContact O-N 3.04Å; F323-F499 HydrophobicContact CD2-CD1 4.4Å; F323-F499 AromaticContact CD2-CE1 3.76Å; F323-F499 HydrophobicContact CD2-CE1 3.76Å; F323-F499 HydrophobicContact CD2-CZ 4.31Å; F323-F499 HydrophobicContact CE2-CE1 4.28Å; F323-F499 HydrophobicContact CG-CE1 4.4Å
324	R	61.8	Low	76.1	Confident	100 Å²	100	47.8 Å²	47.8	38%	0.377	23%	0.225	S	C	.	.	H	α-helix	trans	-88.9	-40.1	-161.7	-141.7	175.2	-173.3	168	5	114	N321 H326 R327 D328	N321-R324 WeakPolarHBondContact O-CB 3.31Å; N321-R324 PolarHBondContact O-N 3.3Å; R324-H326 VanDerWaalsContact C-N 3.28Å; R324-H326 PolarHBondContact O-N 3.24Å; R324-R327 CarbonylContact O-C 3.38Å; R324-R327 PolarHBondContact O-N 3.41Å; R324-D328 VanDerWaalsContact O-CB 3.31Å; R324-D328 WeakPolarHBondContact O-CB 3.45Å; R324-D328 PolarHBondContact O-N 3.42Å
325	T	59.5	Low	76.2	Confident	0 Å²	0	49.8 Å²	49.8	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-59.2	-39.5	178.6	-57.5	0	0	0	0	112.3	F83 L86 Q90 S329	F83-T325 HydrophobicContact CE2-CG2 4.31Å; L86-T325 HydrophobicContact CB-CG2 4.49Å; Q90-T325 PolarHBondContact OE1-OG1 3.28Å; T325-S329 PolarHBondContact O-N 3.25Å
326	H	68.1	Low	76.4	Confident	35 Å²	35	49.6 Å²	49.6	16%	0.162	24%	0.236	C	C	.	.	H	α-helix	trans	-64.3	-42.7	173.2	167	52.3	0	0	0	112.5	F83 R324 S329 I330 F505	F83-H326 HydrophobicContact CE2-CB 4.21Å; F83-H326 HydrophobicContact CZ-CB 4.31Å; R324-H326 VanDerWaalsContact C-N 3.28Å; R324-H326 PolarHBondContact O-N 3.24Å; H326-S329 PolarHBondContact O-OG 2.93Å; H326-I330 WeakPolarHBondContact CE1-CD1 3.49Å; H326-I330 PolarHBondContact O-N 2.97Å; H326-F505 AromaticContact CE1-CE2 3.32Å; H326-F505 WeakPolarHBondContact CE1-CE2 3.38Å; H326-F505 AromaticContact CE1-CZ 3.65Å; H326-F505 AromaticContact ND1-CE2 3.67Å; H326-F505 AromaticContact ND1-CZ 3.8Å
327	R	76.5	Confident	76.6	Confident	122 Å²	122	49.5 Å²	49.5	46%	0.46	24%	0.236	S	C	.	.	H	α-helix	trans	-69.3	-39.3	177.9	-164.5	-174.2	70.9	171	8.3	111.6	R324 I330 I331	R324-R327 CarbonylContact O-C 3.38Å; R324-R327 PolarHBondContact O-N 3.41Å; R327-I330 PolarHBondContact O-N 3.48Å; R327-I331 HydrophobicContact CG-CD1 3.8Å; R327-I331 HydrophobicContact CG-CG1 4.38Å; R327-I331 WeakPolarHBondContact O-CB 3.49Å; R327-I331 VanDerWaalsContact O-CG1 3.24Å; R327-I331 WeakPolarHBondContact O-CG1 3.33Å; R327-I331 PolarHBondContact O-N 2.84Å
328	D	79.2	Confident	77.1	Confident	4 Å²	4	48.8 Å²	48.8	2%	0.021	24%	0.243	C	C	.	.	H	α-helix	trans	-66.9	-40.8	-179.3	-65.7	-16.7	0	0	0	109.9	Q34 F37 V38 R324 I330 I331 I332	Q34-D328 PolarHBondContact NE2-OD2 3.25Å; F37-D328 HydrophobicContact CE1-CB 4.48Å; V38-D328 HydrophobicContact CG2-CB 4.24Å; R324-D328 VanDerWaalsContact O-CB 3.31Å; R324-D328 WeakPolarHBondContact O-CB 3.45Å; R324-D328 PolarHBondContact O-N 3.42Å; D328-I330 VanDerWaalsContact C-N 3.32Å; D328-I330 PolarHBondContact O-N 3.16Å; D328-I331 PolarHBondContact O-N 3.08Å; D328-I332 HydrophobicContact CB-CD1 4.37Å; D328-I332 WeakPolarHBondContact O-CB 3.47Å; D328-I332 VanDerWaalsContact O-CD1 3.24Å; D328-I332 WeakPolarHBondContact O-CD1 3.41Å; D328-I332 WeakPolarHBondContact O-CG1 3.45Å; D328-I332 PolarHBondContact O-N 2.91Å
329	S	81.3	Confident	77.8	Confident	0 Å²	0	49 Å²	49	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-59.9	-40.7	174.5	69.2	0	0	0	0	112.6	T325 H326 S333	T325-S329 PolarHBondContact O-N 3.25Å; H326-S329 PolarHBondContact O-OG 2.93Å; S329-S333 VanDerWaalsContact O-CB 3.31Å; S329-S333 WeakPolarHBondContact O-CB 3.41Å; S329-S333 PolarHBondContact O-N 3.45Å; S329-S333 PolarHBondContact O-OG 3.49Å
330	I	87.8	Confident	78.9	Confident	51 Å²	51	44.2 Å²	44.2	26%	0.262	22%	0.222	S	C	.	.	H	α-helix	trans	-66.9	-50.1	174.5	-69.4	175.1	0	0	0	110.9	I79 H326 R327 D328 I332 S333 I334	I79-I330 HydrophobicContact CG2-CG1 4.05Å; H326-I330 WeakPolarHBondContact CE1-CD1 3.49Å; H326-I330 PolarHBondContact O-N 2.97Å; R327-I330 PolarHBondContact O-N 3.48Å; D328-I330 VanDerWaalsContact C-N 3.32Å; D328-I330 PolarHBondContact O-N 3.16Å; I330-I332 PolarHBondContact O-N 3.32Å; I330-S333 PolarHBondContact O-N 2.89Å; I330-I334 HydrophobicContact CG2-CD1 3.49Å; I330-I334 VanDerWaalsContact CG2-CD1 3.49Å; I330-I334 HydrophobicContact CG2-CG1 4.23Å; I330-I334 WeakPolarHBondContact O-CB 3.41Å; I330-I334 VanDerWaalsContact O-CG1 3.3Å; I330-I334 WeakPolarHBondContact O-CG1 3.34Å; I330-I334 PolarHBondContact O-N 3.47Å
331	I	90.2	Very high	80.4	Confident	66 Å²	66	44.6 Å²	44.6	34%	0.338	23%	0.226	S	C	.	.	H	α-helix	trans	-59	-50	-178.2	-71.7	167.1	0	0	0	110.2	R327 D328 S333 I334 T335	R327-I331 HydrophobicContact CG-CD1 3.8Å; R327-I331 HydrophobicContact CG-CG1 4.38Å; R327-I331 WeakPolarHBondContact O-CB 3.49Å; R327-I331 VanDerWaalsContact O-CG1 3.24Å; R327-I331 WeakPolarHBondContact O-CG1 3.33Å; R327-I331 PolarHBondContact O-N 2.84Å; D328-I331 PolarHBondContact O-N 3.08Å; I331-S333 VanDerWaalsContact C-N 3.34Å; I331-S333 PolarHBondContact O-N 3.49Å; I331-I334 PolarHBondContact O-N 3.26Å; I331-T335 VanDerWaalsContact O-CB 3.31Å; I331-T335 WeakPolarHBondContact O-CB 3.23Å; I331-T335 PolarHBondContact O-N 3.12Å; I331-T335 PolarHBondContact O-OG1 3.47Å
332	I	90.8	Very high	82.4	Confident	0 Å²	0	41.4 Å²	41.4	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-60.6	-45.6	-178.5	-63.8	156.7	0	0	0	110.5	F37 V38 S41 V42 F82 D328 I330 T335 N336	F37-I332 HydrophobicContact CE1-CD1 4.48Å; V38-I332 HydrophobicContact CG1-CG1 4.14Å; S41-I332 VanDerWaalsContact CB-CD1 3.45Å; V42-I332 HydrophobicContact CG2-CB 4.39Å; V42-I332 HydrophobicContact CG2-CG1 4.1Å; V42-I332 HydrophobicContact CG2-CG2 4.15Å; F82-I332 HydrophobicContact CE1-CB 4.05Å; F82-I332 HydrophobicContact CE1-CD1 4.1Å; F82-I332 HydrophobicContact CE1-CG2 3.98Å; F82-I332 HydrophobicContact CE2-CG2 4.31Å; F82-I332 HydrophobicContact CZ-CB 4.1Å; F82-I332 HydrophobicContact CZ-CD1 4.42Å; F82-I332 HydrophobicContact CZ-CG2 3.49Å; F82-I332 VanDerWaalsContact CZ-CG2 3.49Å; D328-I332 HydrophobicContact CB-CD1 4.37Å; D328-I332 WeakPolarHBondContact O-CB 3.47Å; D328-I332 VanDerWaalsContact O-CD1 3.24Å; D328-I332 WeakPolarHBondContact O-CD1 3.41Å; D328-I332 WeakPolarHBondContact O-CG1 3.45Å; D328-I332 PolarHBondContact O-N 2.91Å; I330-I332 PolarHBondContact O-N 3.32Å; I332-T335 PolarHBondContact O-N 2.98Å; I332-N336 WeakPolarHBondContact O-CB 3.41Å; I332-N336 PolarHBondContact O-N 2.99Å
333	S	91.9	Very high	84.8	Confident	0 Å²	0	38.9 Å²	38.9	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-65.3	-42.2	-179.7	-58	0	0	0	0	112.4	S329 I330 I331 N336 C337	S329-S333 VanDerWaalsContact O-CB 3.31Å; S329-S333 WeakPolarHBondContact O-CB 3.41Å; S329-S333 PolarHBondContact O-N 3.45Å; S329-S333 PolarHBondContact O-OG 3.49Å; I330-S333 PolarHBondContact O-N 2.89Å; I331-S333 VanDerWaalsContact C-N 3.34Å; I331-S333 PolarHBondContact O-N 3.49Å; S333-N336 PolarHBondContact O-N 3.47Å; S333-C337 PolarHBondContact O-N 3.01Å; S333-C337 VanDerWaalsContact O-N 3.13Å; S333-C337 PolarHBondContact O-SG 2.76Å
334	I	93.1	Very high	86.8	Confident	90 Å²	90	31.7 Å²	31.7	46%	0.462	16%	0.156	S	C	.	.	H	α-helix	trans	-67.1	-46.3	176.9	-69.6	175.5	0	0	0	110.5	I330 I331 N336 C337 A338	I330-I334 HydrophobicContact CG2-CD1 3.49Å; I330-I334 VanDerWaalsContact CG2-CD1 3.49Å; I330-I334 HydrophobicContact CG2-CG1 4.23Å; I330-I334 WeakPolarHBondContact O-CB 3.41Å; I330-I334 VanDerWaalsContact O-CG1 3.3Å; I330-I334 WeakPolarHBondContact O-CG1 3.34Å; I330-I334 PolarHBondContact O-N 3.47Å; I331-I334 PolarHBondContact O-N 3.26Å; I334-N336 VanDerWaalsContact C-N 3.28Å; I334-N336 PolarHBondContact O-N 3.15Å; I334-C337 PolarHBondContact O-N 3.27Å; I334-A338 WeakPolarHBondContact O-CB 3.2Å; I334-A338 PolarHBondContact O-N 2.93Å
335	T	94.1	Very high	88.4	Confident	43 Å²	43	29.5 Å²	29.5	26%	0.264	15%	0.149	S	C	.	.	H	α-helix	trans	-57.6	-43.9	176.5	-65.8	0	0	0	0	110.7	V42 Y254 I331 I332 A338 T339	V42-T335 HydrophobicContact CG1-CG2 3.9Å; V42-T335 HydrophobicContact CG2-CG2 4.23Å; Y254-T335 WeakPolarHBondContact OH-CG2 3.23Å; I331-T335 VanDerWaalsContact O-CB 3.31Å; I331-T335 WeakPolarHBondContact O-CB 3.23Å; I331-T335 PolarHBondContact O-N 3.12Å; I331-T335 PolarHBondContact O-OG1 3.47Å; I332-T335 PolarHBondContact O-N 2.98Å; T335-A338 PolarHBondContact O-N 3.43Å; T335-T339 WeakPolarHBondContact O-CB 3.06Å; T335-T339 PolarHBondContact O-N 3Å; T335-T339 PolarHBondContact O-OG1 3.28Å
336	N	94.1	Very high	90	Very high	0 Å²	0	29.5 Å²	29.5	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-56.6	-53.8	175.8	174.1	55	0	0	0	112.2	A45 V46 N50 S301 L302 I332 S333 I334 T339 S340	A45-N336 HydrophobicContact CB-CB 4Å; A45-N336 PolarHBondContact O-OD1 2.91Å; V46-N336 HydrophobicContact CG2-CB 4.28Å; N50-N336 PolarHBondContact ND2-O 3.27Å; N50-N336 PolarHBondContact ND2-OD1 3.12Å; S301-N336 PolarHBondContact OG-ND2 3.35Å; S301-N336 PolarHBondContact OG-OD1 2.69Å; S301-N336 VanDerWaalsContact OG-OD1 3.07Å; L302-N336 HydrophobicContact CD2-CB 4.15Å; L302-N336 WeakPolarHBondContact CD2-ND2 3.48Å; I332-N336 WeakPolarHBondContact O-CB 3.41Å; I332-N336 PolarHBondContact O-N 2.99Å; S333-N336 PolarHBondContact O-N 3.47Å; I334-N336 VanDerWaalsContact C-N 3.28Å; I334-N336 PolarHBondContact O-N 3.15Å; N336-T339 WeakPolarHBondContact O-CB 3.37Å; N336-T339 PolarHBondContact O-N 2.9Å; N336-S340 PolarHBondContact O-N 2.76Å; N336-S340 PolarHBondContact O-OG 3.44Å
337	C	93.3	Very high	91.1	Very high	3 Å²	3	28 Å²	28	2%	0.02	14%	0.142	C	C	.	.	H	α-helix	trans	-68.6	-37.7	-178.3	-65.6	0	0	0	0	113.1	Y70 L74 S333 I334 T339 S340 V341	Y70-C337 HydrophobicContact CE1-CB 3.96Å; Y70-C337 PolarHBondContact OH-SG 2.96Å; L74-C337 WeakPolarHBondContact CD1-SG 3.43Å; L74-C337 HydrophobicContact CD2-CB 3.82Å; L74-C337 WeakPolarHBondContact CD2-SG 3.36Å; S333-C337 PolarHBondContact O-N 3.01Å; S333-C337 VanDerWaalsContact O-N 3.13Å; S333-C337 PolarHBondContact O-SG 2.76Å; I334-C337 PolarHBondContact O-N 3.27Å; C337-T339 VanDerWaalsContact C-N 3.27Å; C337-T339 PolarHBondContact O-N 2.78Å; C337-S340 WeakPolarHBondContact O-CB 3.5Å; C337-S340 PolarHBondContact O-N 3.43Å; C337-V341 WeakPolarHBondContact O-CG2 3.25Å; C337-V341 PolarHBondContact O-N 2.94Å
338	A	94.7	Very high	91.8	Very high	54 Å²	54	22.3 Å²	22.3	45%	0.446	12%	0.121	S	C	.	.	H	α-helix	trans	-61.6	-38.8	174.1	0	0	0	0	0	111	I334 T335 V341 Y342	I334-A338 WeakPolarHBondContact O-CB 3.2Å; I334-A338 PolarHBondContact O-N 2.93Å; T335-A338 PolarHBondContact O-N 3.43Å; A338-V341 PolarHBondContact O-N 2.94Å; A338-Y342 VanDerWaalsContact O-CB 3.25Å; A338-Y342 WeakPolarHBondContact O-CB 3.49Å; A338-Y342 PolarHBondContact O-N 2.89Å
339	T	94.9	Very high	92.5	Very high	7 Å²	7	22.1 Å²	22.1	4%	0.043	12%	0.12	C	C	.	.	H	α-helix	trans	-65.4	-41.2	175.9	-52.7	0	0	0	0	111.7	V46 Y254 L257 T335 N336 C337 V341 Y342 A343	V46-T339 HydrophobicContact CG1-CG2 3.59Å; V46-T339 HydrophobicContact CG2-CG2 4.44Å; Y254-T339 HydrophobicContact CE1-CG2 3.82Å; Y254-T339 VanDerWaalsContact CE1-OG1 3.28Å; Y254-T339 WeakPolarHBondContact CE1-OG1 3.48Å; Y254-T339 PolarHBondContact OH-OG1 2.86Å; L257-T339 HydrophobicContact CD1-CG2 4.3Å; T335-T339 WeakPolarHBondContact O-CB 3.06Å; T335-T339 PolarHBondContact O-N 3Å; T335-T339 PolarHBondContact O-OG1 3.28Å; N336-T339 WeakPolarHBondContact O-CB 3.37Å; N336-T339 PolarHBondContact O-N 2.9Å; C337-T339 VanDerWaalsContact C-N 3.27Å; C337-T339 PolarHBondContact O-N 2.78Å; T339-V341 PolarHBondContact O-N 2.91Å; T339-Y342 PolarHBondContact O-N 3.46Å; T339-A343 VanDerWaalsContact O-CB 3.25Å; T339-A343 WeakPolarHBondContact O-CB 3.4Å; T339-A343 PolarHBondContact O-N 3.38Å
340	S	94.6	Very high	92.9	Very high	0 Å²	0	22.3 Å²	22.3	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-59.5	-46.1	174.1	-51.3	0	0	0	0	112	N50 F54 N336 C337 G344	N50-S340 PolarHBondContact ND2-OG 2.85Å; F54-S340 VanDerWaalsContact CD1-O 3.24Å; F54-S340 WeakPolarHBondContact CD1-O 3.39Å; F54-S340 VanDerWaalsContact CG-CB 3.5Å; N336-S340 PolarHBondContact O-N 2.76Å; N336-S340 PolarHBondContact O-OG 3.44Å; C337-S340 WeakPolarHBondContact O-CB 3.5Å; C337-S340 PolarHBondContact O-N 3.43Å; S340-G344 PolarHBondContact O-N 2.88Å
341	V	94.9	Very high	93	Very high	30 Å²	30	19.9 Å²	19.9	18%	0.182	11%	0.109	C	C	.	.	H	α-helix	trans	-64	-44.5	179	174.6	0	0	0	0	110.7	F54 M67 F71 Y277 C337 A338 T339 G344 F345	F54-V341 HydrophobicContact CE1-CG2 4.06Å; F54-V341 HydrophobicContact CZ-CG2 3.9Å; M67-V341 HydrophobicContact CE-CG1 4.46Å; M67-V341 HydrophobicContact CE-CG2 4.14Å; M67-V341 HydrophobicContact SD-CG2 4.09Å; F71-V341 HydrophobicContact CZ-CG2 4.31Å; Y277-V341 WeakPolarHBondContact OH-CA 3.21Å; Y277-V341 PolarHBondContact OH-O 2.98Å; C337-V341 WeakPolarHBondContact O-CG2 3.25Å; C337-V341 PolarHBondContact O-N 2.94Å; A338-V341 PolarHBondContact O-N 2.94Å; T339-V341 PolarHBondContact O-N 2.91Å; V341-G344 PolarHBondContact O-N 3.18Å; V341-F345 HydrophobicContact CG1-CD2 4.29Å; V341-F345 HydrophobicContact CG1-CE2 3.9Å; V341-F345 VanDerWaalsContact O-CD2 3.26Å; V341-F345 WeakPolarHBondContact O-CD2 3.47Å; V341-F345 PolarHBondContact O-N 2.73Å
342	Y	95.8	Very high	93.1	Very high	60 Å²	60	16.8 Å²	16.8	24%	0.235	9%	0.093	C	C	.	.	H	α-helix	trans	-65.2	-45.1	179.2	-175.1	-119.1	0	0	0	112.7	L257 T258 F261 A338 T339 G344 F345 V346	L257-Y342 HydrophobicContact CB-CD1 4.24Å; L257-Y342 HydrophobicContact CB-CE1 3.8Å; L257-Y342 HydrophobicContact CD1-CD1 4.39Å; T258-Y342 VanDerWaalsContact CA-OH 3.3Å; T258-Y342 WeakPolarHBondContact CA-OH 3.29Å; T258-Y342 PolarHBondContact OG1-OH 3.5Å; F261-Y342 HydrophobicContact CB-CE2 4.47Å; F261-Y342 WeakPolarHBondContact CB-OH 3.23Å; F261-Y342 HydrophobicContact CD1-CE2 4.24Å; F261-Y342 HydrophobicContact CD2-CE2 4.39Å; F261-Y342 HydrophobicContact CG-CE2 4.1Å; A338-Y342 VanDerWaalsContact O-CB 3.25Å; A338-Y342 WeakPolarHBondContact O-CB 3.49Å; A338-Y342 PolarHBondContact O-N 2.89Å; T339-Y342 PolarHBondContact O-N 3.46Å; Y342-G344 PolarHBondContact O-N 3.21Å; Y342-F345 WeakPolarHBondContact O-CB 3.46Å; Y342-F345 PolarHBondContact O-N 3.11Å; Y342-F345 VanDerWaalsContact O-N 3.08Å; Y342-V346 PolarHBondContact O-N 3.17Å
343	A	93.4	Very high	93	Very high	0 Å²	0	17.5 Å²	17.5	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-58.3	-40.4	172.9	0	0	0	0	0	110.7	V51 L257 T339 F345 V346 I347	V51-A343 HydrophobicContact CG2-CB 4.26Å; L257-A343 HydrophobicContact CD2-CB 4.4Å; T339-A343 VanDerWaalsContact O-CB 3.25Å; T339-A343 WeakPolarHBondContact O-CB 3.4Å; T339-A343 PolarHBondContact O-N 3.38Å; A343-F345 VanDerWaalsContact C-N 3.32Å; A343-F345 PolarHBondContact O-N 2.91Å; A343-V346 WeakPolarHBondContact O-CB 3.45Å; A343-V346 PolarHBondContact O-N 3.16Å; A343-V346 VanDerWaalsContact O-N 3.11Å; A343-I347 VanDerWaalsContact O-CB 3.31Å; A343-I347 WeakPolarHBondContact O-CB 3.39Å; A343-I347 WeakPolarHBondContact O-CG1 3.48Å; A343-I347 PolarHBondContact O-N 2.83Å
344	G	93.1	Very high	92.8	Very high	0 Å²	0	17.7 Å²	17.7	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-54.4	-42.9	172.5	0	0	0	0	0	113.8	S340 V341 Y342 I347 F348	S340-G344 PolarHBondContact O-N 2.88Å; V341-G344 PolarHBondContact O-N 3.18Å; Y342-G344 PolarHBondContact O-N 3.21Å; G344-I347 PolarHBondContact O-N 2.92Å; G344-F348 WeakPolarHBondContact O-CB 3.32Å; G344-F348 VanDerWaalsContact O-CD2 3.31Å; G344-F348 WeakPolarHBondContact O-CD2 3.44Å; G344-F348 PolarHBondContact O-N 3.49Å
345	F	94.3	Very high	92.5	Very high	54 Å²	54	13.6 Å²	13.6	24%	0.237	8%	0.077	C	C	.	.	H	α-helix	trans	-62.1	-45.5	174	-79.7	-81.3	0	0	0	112.7	F261 I274 Y277 L278 V341 Y342 A343 S349	F261-F345 HydrophobicContact CD2-CB 4.24Å; F261-F345 HydrophobicContact CE2-CB 3.94Å; I274-F345 HydrophobicContact CG2-CD1 4.14Å; I274-F345 HydrophobicContact CG2-CE1 3.99Å; Y277-F345 HydrophobicContact CD1-CD1 4.49Å; Y277-F345 HydrophobicContact CE1-CD1 4.48Å; Y277-F345 AromaticContact CE1-CD2 3.98Å; Y277-F345 HydrophobicContact CE1-CD2 3.98Å; Y277-F345 HydrophobicContact CE1-CE2 4.09Å; Y277-F345 HydrophobicContact CE1-CG 4.18Å; Y277-F345 HydrophobicContact CE1-CZ 4.41Å; L278-F345 HydrophobicContact CD1-CE1 3.72Å; L278-F345 HydrophobicContact CD1-CZ 3.82Å; L278-F345 HydrophobicContact CD2-CE1 4.49Å; L278-F345 HydrophobicContact CD2-CZ 4.04Å; L278-F345 HydrophobicContact CG-CE1 4.33Å; L278-F345 HydrophobicContact CG-CZ 4.34Å; V341-F345 HydrophobicContact CG1-CD2 4.29Å; V341-F345 HydrophobicContact CG1-CE2 3.9Å; V341-F345 VanDerWaalsContact O-CD2 3.26Å; V341-F345 WeakPolarHBondContact O-CD2 3.47Å; V341-F345 PolarHBondContact O-N 2.73Å; Y342-F345 WeakPolarHBondContact O-CB 3.46Å; Y342-F345 PolarHBondContact O-N 3.11Å; Y342-F345 VanDerWaalsContact O-N 3.08Å; A343-F345 VanDerWaalsContact C-N 3.32Å; A343-F345 PolarHBondContact O-N 2.91Å; F345-S349 VanDerWaalsContact O-CB 3.28Å; F345-S349 WeakPolarHBondContact O-CB 3.33Å; F345-S349 PolarHBondContact O-N 3.42Å; F345-S349 PolarHBondContact O-OG 2.95Å
346	V	93.6	Very high	92.3	Very high	1 Å²	1	15.6 Å²	15.6	1%	0.006	8%	0.083	C	C	.	.	H	α-helix	trans	-57.5	-53.6	177	177.7	0	0	0	0	110.1	L257 L260 F261 Y342 A343 F348 S349 I350	L257-V346 HydrophobicContact CB-CG2 4.39Å; L257-V346 HydrophobicContact CD2-CB 4.44Å; L257-V346 HydrophobicContact CD2-CG1 4.38Å; L257-V346 HydrophobicContact CD2-CG2 4.17Å; L257-V346 WeakPolarHBondContact O-CG2 3.49Å; L260-V346 HydrophobicContact CB-CG1 3.61Å; F261-V346 HydrophobicContact CB-CG2 3.78Å; F261-V346 HydrophobicContact CD2-CG2 4.29Å; F261-V346 HydrophobicContact CG-CG2 4.47Å; Y342-V346 PolarHBondContact O-N 3.17Å; A343-V346 WeakPolarHBondContact O-CB 3.45Å; A343-V346 PolarHBondContact O-N 3.16Å; A343-V346 VanDerWaalsContact O-N 3.11Å; V346-F348 PolarHBondContact O-N 2.89Å; V346-S349 PolarHBondContact O-N 3.31Å; V346-S349 PolarHBondContact O-OG 3.35Å; V346-I350 HydrophobicContact CG1-CD1 4.43Å; V346-I350 PolarHBondContact O-N 3.2Å
347	I	90.8	Very high	91.8	Very high	2 Å²	2	18.9 Å²	18.9	1%	0.01	10%	0.1	C	C	.	.	H	α-helix	trans	-53.4	-57.5	179.8	-72.8	-12.3	0	0	0	111.6	V51 P55 A343 G344 S349 I350 L351 Y377	V51-I347 HydrophobicContact CG1-CD1 3.77Å; V51-I347 HydrophobicContact CG1-CG1 4.41Å; V51-I347 WeakPolarHBondContact O-CG1 3.24Å; P55-I347 HydrophobicContact CB-CB 4.38Å; P55-I347 HydrophobicContact CB-CG2 3.84Å; P55-I347 HydrophobicContact CG-CB 4.4Å; P55-I347 HydrophobicContact CG-CG1 4.09Å; P55-I347 HydrophobicContact CG-CG2 4.34Å; A343-I347 VanDerWaalsContact O-CB 3.31Å; A343-I347 WeakPolarHBondContact O-CB 3.39Å; A343-I347 WeakPolarHBondContact O-CG1 3.48Å; A343-I347 PolarHBondContact O-N 2.83Å; G344-I347 PolarHBondContact O-N 2.92Å; I347-S349 VanDerWaalsContact C-N 3.32Å; I347-S349 PolarHBondContact O-N 3.34Å; I347-I350 PolarHBondContact O-N 3.22Å; I347-L351 HydrophobicContact CG2-CD1 3.9Å; I347-L351 WeakPolarHBondContact O-CG 3.34Å; I347-L351 PolarHBondContact O-N 3.07Å; I347-Y377 HydrophobicContact CB-CE1 4.31Å; I347-Y377 WeakPolarHBondContact CB-OH 3.07Å; I347-Y377 HydrophobicContact CD1-CE1 3.54Å; I347-Y377 HydrophobicContact CD1-CE2 4.12Å; I347-Y377 WeakPolarHBondContact CD1-OH 3.29Å; I347-Y377 HydrophobicContact CG1-CE1 4.16Å; I347-Y377 WeakPolarHBondContact CG1-OH 3.5Å; I347-Y377 HydrophobicContact CG2-CE1 4.41Å; I347-Y377 WeakPolarHBondContact CG2-OH 3.08Å
348	F	91.7	Very high	91.1	Very high	3 Å²	3	21.4 Å²	21.4	1%	0.013	11%	0.113	C	C	.	.	H	α-helix	trans	-73.2	-25.6	-173.1	-83.8	-75.6	0	0	0	112.9	P55 Y59 G273 Y276 Y277 G344 V346 I350 L351 G352 V362	P55-F348 HydrophobicContact CB-CD2 4.2Å; P55-F348 HydrophobicContact CB-CE2 3.66Å; P55-F348 WeakPolarHBondContact O-CE2 3.42Å; Y59-F348 HydrophobicContact CD1-CE1 4.45Å; Y59-F348 AromaticContact CD1-CZ 3.71Å; Y59-F348 HydrophobicContact CD1-CZ 3.71Å; Y59-F348 HydrophobicContact CG-CZ 4.09Å; G273-F348 VanDerWaalsContact CA-O 3.3Å; G273-F348 WeakPolarHBondContact CA-O 3.44Å; Y276-F348 HydrophobicContact CD1-CD1 4.38Å; Y276-F348 AromaticContact CD1-CE1 3.83Å; Y276-F348 HydrophobicContact CD1-CE1 3.83Å; Y276-F348 HydrophobicContact CE1-CE1 4.39Å; Y277-F348 HydrophobicContact CD1-CD2 4.32Å; Y277-F348 AromaticContact CD2-CD2 3.58Å; Y277-F348 HydrophobicContact CD2-CD2 3.58Å; Y277-F348 AromaticContact CD2-CE2 3.6Å; Y277-F348 HydrophobicContact CD2-CE2 3.6Å; Y277-F348 HydrophobicContact CD2-CG 4.49Å; Y277-F348 HydrophobicContact CE2-CD2 4.32Å; Y277-F348 HydrophobicContact CE2-CE2 4.31Å; Y277-F348 HydrophobicContact CG-CB 4.44Å; Y277-F348 AromaticContact CG-CD2 3.58Å; Y277-F348 HydrophobicContact CG-CD2 3.58Å; Y277-F348 HydrophobicContact CG-CE2 4.06Å; Y277-F348 HydrophobicContact CG-CG 4.12Å; G344-F348 WeakPolarHBondContact O-CB 3.32Å; G344-F348 VanDerWaalsContact O-CD2 3.31Å; G344-F348 WeakPolarHBondContact O-CD2 3.44Å; G344-F348 PolarHBondContact O-N 3.49Å; V346-F348 PolarHBondContact O-N 2.89Å; F348-I350 VanDerWaalsContact C-N 3.35Å; F348-L351 HydrophobicContact CD1-CD1 4.44Å; F348-L351 HydrophobicContact CE1-CD1 4.47Å; F348-G352 PolarHBondContact O-N 3.46Å; F348-V362 HydrophobicContact CD1-CG1 4.19Å; F348-V362 HydrophobicContact CE1-CG1 4.24Å
349	S	93.8	Very high	90.5	Very high	0 Å²	0	26 Å²	26	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-62.5	-42.5	171.8	70.9	0	0	0	0	111.9	G264 A270 F345 V346 I347 F353	G264-S349 WeakPolarHBondContact CA-OG 3.21Å; A270-S349 WeakPolarHBondContact CA-O 3.41Å; F345-S349 VanDerWaalsContact O-CB 3.28Å; F345-S349 WeakPolarHBondContact O-CB 3.33Å; F345-S349 PolarHBondContact O-N 3.42Å; F345-S349 PolarHBondContact O-OG 2.95Å; V346-S349 PolarHBondContact O-N 3.31Å; V346-S349 PolarHBondContact O-OG 3.35Å; I347-S349 VanDerWaalsContact C-N 3.32Å; I347-S349 PolarHBondContact O-N 3.34Å; S349-F353 PolarHBondContact O-N 3.38Å
350	I	91.1	Very high	90	Very high	4 Å²	4	27.9 Å²	27.9	2%	0.021	14%	0.142	C	C	.	.	H	α-helix	trans	-73.5	-42.7	179	-65.7	172.3	0	0	0	111.1	L260 V346 I347 F348 G352 F353 M354 A380	L260-I350 HydrophobicContact CD2-CD1 4.49Å; V346-I350 HydrophobicContact CG1-CD1 4.43Å; V346-I350 PolarHBondContact O-N 3.2Å; I347-I350 PolarHBondContact O-N 3.22Å; F348-I350 VanDerWaalsContact C-N 3.35Å; I350-G352 VanDerWaalsContact C-N 3.29Å; I350-G352 PolarHBondContact O-N 3.41Å; I350-F353 WeakPolarHBondContact O-CB 3.48Å; I350-F353 PolarHBondContact O-N 2.87Å; I350-M354 PolarHBondContact O-N 2.89Å; I350-M354 VanDerWaalsContact O-N 3.08Å; I350-A380 HydrophobicContact CG2-CB 3.5Å; I350-A380 VanDerWaalsContact CG2-CB 3.5Å
351	L	89	Confident	89.5	Confident	1 Å²	1	31 Å²	31	1%	0.005	16%	0.162	C	C	.	.	H	α-helix	trans	-64.2	-34.2	175.9	-68.4	176	0	0	0	112.3	I347 F348 M354 A355 V365 A366 L372 A376	I347-L351 HydrophobicContact CG2-CD1 3.9Å; I347-L351 WeakPolarHBondContact O-CG 3.34Å; I347-L351 PolarHBondContact O-N 3.07Å; F348-L351 HydrophobicContact CD1-CD1 4.44Å; F348-L351 HydrophobicContact CE1-CD1 4.47Å; L351-M354 HydrophobicContact CD2-SD 4.3Å; L351-M354 PolarHBondContact O-N 2.86Å; L351-A355 WeakPolarHBondContact O-CB 3.38Å; L351-A355 PolarHBondContact O-N 2.79Å; L351-V365 HydrophobicContact CB-CG2 4.44Å; L351-V365 HydrophobicContact CD2-CG2 4.45Å; L351-A366 HydrophobicContact CD1-CB 4.49Å; L351-L372 HydrophobicContact CD1-CD1 4.16Å; L351-A376 HydrophobicContact CD2-CB 4.36Å
352	G	91.2	Very high	89	Confident	0 Å²	0	30.1 Å²	30.1	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-62.6	-41	174.5	0	0	0	0	0	112.8	G269 F348 I350 H356	G269-G352 CarbonylContact O-C 3.37Å; F348-G352 PolarHBondContact O-N 3.46Å; I350-G352 VanDerWaalsContact C-N 3.29Å; I350-G352 PolarHBondContact O-N 3.41Å; G352-H356 WeakPolarHBondContact O-CB 3.49Å; G352-H356 PolarHBondContact O-N 3.08Å
353	F	90.3	Very high	88.3	Confident	16 Å²	16	30 Å²	30	7%	0.07	17%	0.165	C	C	.	.	H	α-helix	trans	-63.7	-45.4	173.5	163.9	-110.8	0	0	0	112.3	L267 D268 S349 I350 H356 N357 L383 L384	L267-F353 HydrophobicContact CB-CB 3.78Å; L267-F353 HydrophobicContact CB-CD2 3.7Å; L267-F353 HydrophobicContact CB-CE2 4.36Å; L267-F353 HydrophobicContact CB-CG 3.76Å; L267-F353 HydrophobicContact CD1-CB 4.01Å; L267-F353 HydrophobicContact CD1-CD1 3.77Å; L267-F353 HydrophobicContact CD1-CD2 4.43Å; L267-F353 HydrophobicContact CD1-CE1 4.27Å; L267-F353 HydrophobicContact CD1-CG 3.83Å; L267-F353 HydrophobicContact CD2-CD1 4.45Å; L267-F353 HydrophobicContact CD2-CD2 4.18Å; L267-F353 HydrophobicContact CD2-CE1 4.29Å; L267-F353 HydrophobicContact CD2-CE2 4.04Å; L267-F353 HydrophobicContact CD2-CG 4.37Å; L267-F353 HydrophobicContact CD2-CZ 4.09Å; L267-F353 HydrophobicContact CG-CB 4.48Å; L267-F353 HydrophobicContact CG-CD1 4.46Å; L267-F353 HydrophobicContact CG-CD2 4.31Å; L267-F353 HydrophobicContact CG-CG 4.18Å; D268-F353 WeakPolarHBondContact O-CA 3.46Å; D268-F353 WeakPolarHBondContact O-CD2 3.5Å; S349-F353 PolarHBondContact O-N 3.38Å; I350-F353 WeakPolarHBondContact O-CB 3.48Å; I350-F353 PolarHBondContact O-N 2.87Å; F353-H356 PolarHBondContact O-N 3.22Å; F353-N357 WeakPolarHBondContact CE2-ND2 3.38Å; F353-N357 WeakPolarHBondContact CZ-ND2 3.5Å; F353-N357 PolarHBondContact O-N 2.99Å; F353-L383 HydrophobicContact CE1-CB 3.55Å; F353-L383 HydrophobicContact CE1-CD1 4.32Å; F353-L383 HydrophobicContact CZ-CB 4.08Å; F353-L384 HydrophobicContact CD1-CD2 4.4Å; F353-L384 HydrophobicContact CE1-CD2 3.89Å
354	M	87.6	Confident	87.6	Confident	3 Å²	3	36.7 Å²	36.7	2%	0.015	20%	0.196	C	C	.	.	H	α-helix	trans	-58.9	-49.3	175.4	173.1	-173.4	-118.7	0	0	111.7	I350 L351 H356 N357 L358 V365 E379 A380 L383	I350-M354 PolarHBondContact O-N 2.89Å; I350-M354 VanDerWaalsContact O-N 3.08Å; L351-M354 HydrophobicContact CD2-SD 4.3Å; L351-M354 PolarHBondContact O-N 2.86Å; M354-H356 VanDerWaalsContact C-N 3.28Å; M354-H356 PolarHBondContact O-N 2.91Å; M354-N357 PolarHBondContact O-N 3.22Å; M354-L358 HydrophobicContact CG-CD1 3.67Å; M354-L358 HydrophobicContact CG-CG 4.35Å; M354-L358 WeakPolarHBondContact O-CB 3.45Å; M354-L358 WeakPolarHBondContact O-CG 3.37Å; M354-L358 PolarHBondContact O-N 2.98Å; M354-V365 HydrophobicContact CG-CB 4.44Å; M354-V365 HydrophobicContact CG-CG1 4.08Å; M354-V365 HydrophobicContact SD-CB 3.79Å; M354-V365 HydrophobicContact SD-CG1 3.94Å; M354-V365 HydrophobicContact SD-CG2 4.44Å; M354-E379 HydrophobicContact CE-CB 3.46Å; M354-E379 VanDerWaalsContact CE-CB 3.46Å; M354-E379 VanDerWaalsContact CE-CD 3.46Å; M354-E379 HydrophobicContact CE-CG 3.29Å; M354-A380 HydrophobicContact CB-CB 4.2Å; M354-A380 HydrophobicContact CE-CB 3.88Å; M354-A380 VanDerWaalsContact CE-N 3.33Å; M354-A380 HydrophobicContact SD-CB 4.07Å; M354-L383 HydrophobicContact CB-CD1 4.31Å; M354-L383 HydrophobicContact CG-CD1 4.33Å
355	A	87.4	Confident	86.9	Confident	5 Å²	5	37.6 Å²	37.6	4%	0.041	20%	0.201	C	C	.	.	H	α-helix	trans	-58	-40.9	177.6	0	0	0	0	0	112.2	L351 L358 N359 V360 V362 V365	L351-A355 WeakPolarHBondContact O-CB 3.38Å; L351-A355 PolarHBondContact O-N 2.79Å; A355-L358 PolarHBondContact O-N 3.33Å; A355-N359 WeakPolarHBondContact O-CA 3.35Å; A355-N359 PolarHBondContact O-N 3.2Å; A355-V360 WeakPolarHBondContact CB-O 3.29Å; A355-V360 PolarHBondContact O-N 2.77Å; A355-V360 VanDerWaalsContact O-N 3.09Å; A355-V362 HydrophobicContact CB-CB 4.42Å; A355-V362 HydrophobicContact CB-CG2 3.74Å; A355-V365 HydrophobicContact CB-CG2 4.13Å
356	H	88	Confident	85.7	Confident	85 Å²	85	35.3 Å²	35.3	39%	0.394	19%	0.192	S	C	.	.	H	α-helix	trans	-64.8	-44.7	176.3	-178	-89.3	0	0	0	112.5	G352 F353 M354 L358 N359	G352-H356 WeakPolarHBondContact O-CB 3.49Å; G352-H356 PolarHBondContact O-N 3.08Å; F353-H356 PolarHBondContact O-N 3.22Å; M354-H356 VanDerWaalsContact C-N 3.28Å; M354-H356 PolarHBondContact O-N 2.91Å; H356-L358 VanDerWaalsContact C-N 3.35Å; H356-N359 PolarHBondContact O-N 3.48Å
357	N	83.9	Confident	84.5	Confident	69 Å²	69	38 Å²	38	37%	0.369	21%	0.207	S	C	.	.	H	α-helix	trans	-69.2	-34.2	178.3	-75	0.4	0	0	0	112.8	F353 M354 N359	F353-N357 WeakPolarHBondContact CE2-ND2 3.38Å; F353-N357 WeakPolarHBondContact CZ-ND2 3.5Å; F353-N357 PolarHBondContact O-N 2.99Å; M354-N357 PolarHBondContact O-N 3.22Å; N357-N359 VanDerWaalsContact C-N 3.31Å
358	L	78.7	Confident	83.3	Confident	55 Å²	55	41.2 Å²	41.2	29%	0.288	22%	0.222	S	C	.	.	H	α-helix	trans	-82	-9.1	178.2	-68.9	179.4	0	0	0	113.2	V160 M354 A355 H356 V360 V365	V160-L358 HydrophobicContact CB-CD2 4.11Å; V160-L358 HydrophobicContact CG1-CD2 3.55Å; V160-L358 HydrophobicContact CG1-CG 4.41Å; V160-L358 HydrophobicContact CG2-CD2 3.83Å; M354-L358 HydrophobicContact CG-CD1 3.67Å; M354-L358 HydrophobicContact CG-CG 4.35Å; M354-L358 WeakPolarHBondContact O-CB 3.45Å; M354-L358 WeakPolarHBondContact O-CG 3.37Å; M354-L358 PolarHBondContact O-N 2.98Å; A355-L358 PolarHBondContact O-N 3.33Å; H356-L358 VanDerWaalsContact C-N 3.35Å; L358-V360 HydrophobicContact CB-CG1 4.35Å; L358-V360 HydrophobicContact CB-CG2 3.67Å; L358-V360 HydrophobicContact CD1-CG2 4.4Å; L358-V360 PolarHBondContact O-N 3.17Å; L358-V365 HydrophobicContact CD1-CG1 4.04Å
359	N	83.6	Confident	82.2	Confident	151 Å²	151	42.1 Å²	42.1	81%	0.807	23%	0.232	S	C	*	.	T	Hydrogen-bonded Turn	trans	52.2	38.2	-172.4	-67.6	-61.5	0	0	0	113.2	A355 H356 N357	A355-N359 WeakPolarHBondContact O-CA 3.35Å; A355-N359 PolarHBondContact O-N 3.2Å; H356-N359 PolarHBondContact O-N 3.48Å; N357-N359 VanDerWaalsContact C-N 3.31Å
360	V	82.9	Confident	81.2	Confident	46 Å²	46	42.9 Å²	42.9	28%	0.279	24%	0.237	S	C	.	.	S	Bend	trans	-119.4	154.6	177.4	-62.9	0	0	0	0	110.1	A355 L358 V365	A355-V360 WeakPolarHBondContact CB-O 3.29Å; A355-V360 PolarHBondContact O-N 2.77Å; A355-V360 VanDerWaalsContact O-N 3.09Å; L358-V360 HydrophobicContact CB-CG1 4.35Å; L358-V360 HydrophobicContact CB-CG2 3.67Å; L358-V360 HydrophobicContact CD1-CG2 4.4Å; L358-V360 PolarHBondContact O-N 3.17Å; V360-V365 HydrophobicContact CG2-CG1 3.63Å
361	P	84.7	Confident	80.7	Confident	66 Å²	66	43 Å²	43	43%	0.429	24%	0.239	S	C	.	.			trans	-64.8	148.8	172.8	28.2	-35.2	0	0	0	111.3	S363 E364	P361-S363 PolarHBondContact O-N 3Å; P361-E364 HydrophobicContact CG-CB 4.4Å; P361-E364 HydrophobicContact CG-CG 3.87Å; P361-E364 WeakPolarHBondContact CG-OE1 3.28Å; P361-E364 PolarHBondContact O-N 2.85Å
362	V	83.9	Confident	80.3	Confident	12 Å²	12	43.1 Å²	43.1	7%	0.073	24%	0.239	C	C	.	.	H	α-helix	trans	-56.5	-26.3	179.2	-179.7	0	0	0	0	112.3	Y276 F348 A355 E364 V365 A366	Y276-V362 HydrophobicContact CD1-CB 4.04Å; Y276-V362 HydrophobicContact CD1-CG1 3.65Å; Y276-V362 HydrophobicContact CD2-CB 4.28Å; Y276-V362 HydrophobicContact CE1-CG1 4.22Å; Y276-V362 HydrophobicContact CG-CB 3.92Å; Y276-V362 HydrophobicContact CG-CG1 3.95Å; F348-V362 HydrophobicContact CD1-CG1 4.19Å; F348-V362 HydrophobicContact CE1-CG1 4.24Å; A355-V362 HydrophobicContact CB-CB 4.42Å; A355-V362 HydrophobicContact CB-CG2 3.74Å; V362-E364 VanDerWaalsContact C-N 3.28Å; V362-E364 PolarHBondContact O-N 3.23Å; V362-V365 VanDerWaalsContact O-CG2 3.25Å; V362-V365 WeakPolarHBondContact O-CG2 3.33Å; V362-V365 PolarHBondContact O-N 2.9Å; V362-A366 VanDerWaalsContact O-CB 3.31Å; V362-A366 WeakPolarHBondContact O-CB 3.33Å; V362-A366 PolarHBondContact O-N 3.15Å
363	S	81.6	Confident	80.1	Confident	58 Å²	58	43.1 Å²	43.1	41%	0.406	24%	0.24	S	C	.	.	H	α-helix	trans	-64.3	-27.4	176.6	51.8	0	0	0	0	114.4	Y276 P361	Y276-S363 WeakPolarHBondContact OH-CB 3.49Å; P361-S363 PolarHBondContact O-N 3Å
364	E	78.4	Confident	80.1	Confident	140 Å²	140	42.4 Å²	42.4	65%	0.654	24%	0.237	S	C	*	.	H	α-helix	trans	-83.4	-24.5	-178.1	-75.1	175.9	-158.9	0	0	112.4	P361 V362	P361-E364 HydrophobicContact CG-CB 4.4Å; P361-E364 HydrophobicContact CG-CG 3.87Å; P361-E364 WeakPolarHBondContact CG-OE1 3.28Å; P361-E364 PolarHBondContact O-N 2.85Å; V362-E364 VanDerWaalsContact C-N 3.28Å; V362-E364 PolarHBondContact O-N 3.23Å
365	V	78.4	Confident	80.2	Confident	18 Å²	18	42.8 Å²	42.8	11%	0.109	24%	0.239	C	C	.	.	H	α-helix	trans	-93.3	-12.2	177.2	-61	0	0	0	0	113.1	L351 M354 A355 L358 V360 V362 D367	L351-V365 HydrophobicContact CB-CG2 4.44Å; L351-V365 HydrophobicContact CD2-CG2 4.45Å; M354-V365 HydrophobicContact CG-CB 4.44Å; M354-V365 HydrophobicContact CG-CG1 4.08Å; M354-V365 HydrophobicContact SD-CB 3.79Å; M354-V365 HydrophobicContact SD-CG1 3.94Å; M354-V365 HydrophobicContact SD-CG2 4.44Å; A355-V365 HydrophobicContact CB-CG2 4.13Å; L358-V365 HydrophobicContact CD1-CG1 4.04Å; V360-V365 HydrophobicContact CG2-CG1 3.63Å; V362-V365 VanDerWaalsContact O-CG2 3.25Å; V362-V365 WeakPolarHBondContact O-CG2 3.33Å; V362-V365 PolarHBondContact O-N 2.9Å; V365-D367 PolarHBondContact O-N 3.44Å
366	A	69.6	Low	80.3	Confident	6 Å²	6	42.8 Å²	42.8	5%	0.05	24%	0.239	C	C	.	.			trans	-89.7	78.7	-177.2	0	0	0	0	0	111.6	Y59 L351 V362	Y59-A366 HydrophobicContact CE1-CB 3.91Å; Y59-A366 PolarHBondContact OH-O 3.06Å; L351-A366 HydrophobicContact CD1-CB 4.49Å; V362-A366 VanDerWaalsContact O-CB 3.31Å; V362-A366 WeakPolarHBondContact O-CB 3.33Å; V362-A366 PolarHBondContact O-N 3.15Å
367	D	66.9	Low	80.2	Confident	57 Å²	57	38.8 Å²	38.8	31%	0.305	22%	0.22	S	C	.	.			trans	-70.7	177.7	174.5	-159.6	4.3	0	0	0	112.4	V365 G371	V365-D367 PolarHBondContact O-N 3.44Å; D367-G371 WeakPolarHBondContact OD2-CA 2.89Å
368	H	65.9	Low	80.5	Confident	71 Å²	71	35.5 Å²	35.5	33%	0.329	20%	0.203	S	C	.	.			trans	-116.8	151.4	-173.8	65.9	-69.1	0	0	0	112.9	Y56 G371	Y56-H368 HydrophobicContact CD2-CB 3.64Å; Y56-H368 HydrophobicContact CE1-CB 4.19Å; Y56-H368 HydrophobicContact CE2-CB 3.23Å; Y56-H368 HydrophobicContact CG-CB 4.32Å; H368-G371 PolarHBondContact O-N 2.98Å
369	G	68.6	Low	81	Confident	22 Å²	22	33.9 Å²	33.9	23%	0.227	19%	0.194	C	C	.	.	T	Hydrogen-bonded Turn	trans	58.1	-137.7	173	0	0	0	0	0	113.3	G371 L372	G369-G371 PolarHBondContact O-N 3.18Å; G369-L372 WeakPolarHBondContact O-CB 3.45Å; G369-L372 PolarHBondContact O-N 3.49Å
370	P	73.4	Confident	81.2	Confident	16 Å²	16	26.7 Å²	26.7	10%	0.104	16%	0.155	C	C	.	.	H	α-helix	trans	-59.1	-27.5	177.5	-24.7	34.8	0	0	0	114.3	W199 L372 A373 F374 L458	W199-P370 HydrophobicContact CZ2-CB 4.46Å; P370-L372 VanDerWaalsContact C-N 3.31Å; P370-L372 PolarHBondContact O-N 3.01Å; P370-A373 PolarHBondContact O-N 3.48Å; P370-A373 VanDerWaalsContact O-N 3.17Å; P370-F374 HydrophobicContact CB-CD2 4.06Å; P370-F374 HydrophobicContact CB-CE2 4.46Å; P370-F374 VanDerWaalsContact O-CD2 3.32Å; P370-F374 WeakPolarHBondContact O-CD2 3.34Å; P370-F374 PolarHBondContact O-N 3.18Å; P370-L458 HydrophobicContact CG-CD2 4.19Å
371	G	79.8	Confident	81.6	Confident	6 Å²	6	24.6 Å²	24.6	6%	0.062	14%	0.142	C	C	.	.	H	α-helix	trans	-61.7	-39.4	177.1	0	0	0	0	0	112	D367 H368 G369 A373 V375 A376	D367-G371 WeakPolarHBondContact OD2-CA 2.89Å; H368-G371 PolarHBondContact O-N 2.98Å; G369-G371 PolarHBondContact O-N 3.18Å; G371-A373 VanDerWaalsContact C-N 3.32Å; G371-A373 PolarHBondContact O-N 3.23Å; G371-V375 WeakPolarHBondContact O-CA 3.4Å; G371-V375 WeakPolarHBondContact O-CB 3.38Å; G371-V375 PolarHBondContact O-N 2.96Å; G371-A376 PolarHBondContact O-N 2.94Å; G371-A376 VanDerWaalsContact O-N 3.08Å
372	L	81.9	Confident	81.9	Confident	3 Å²	3	22.1 Å²	22.1	2%	0.016	13%	0.126	C	C	.	.	I	π-helix	trans	-60.2	-44.7	174.4	-170	66.6	0	0	0	111.5	W52 L351 G369 P370 A376 Y377	W52-L372 HydrophobicContact CB-CD2 4.23Å; W52-L372 VanDerWaalsContact O-CD2 3.31Å; W52-L372 WeakPolarHBondContact O-CD2 3.06Å; L351-L372 HydrophobicContact CD1-CD1 4.16Å; G369-L372 WeakPolarHBondContact O-CB 3.45Å; G369-L372 PolarHBondContact O-N 3.49Å; P370-L372 VanDerWaalsContact C-N 3.31Å; P370-L372 PolarHBondContact O-N 3.01Å; L372-A376 HydrophobicContact CD1-CB 4.09Å; L372-Y377 HydrophobicContact CD1-CE2 4.44Å; L372-Y377 HydrophobicContact CD2-CE2 4.36Å; L372-Y377 HydrophobicContact CG-CE2 3.8Å; L372-Y377 WeakPolarHBondContact O-CD2 3.35Å; L372-Y377 WeakPolarHBondContact O-CE2 3.26Å; L372-Y377 PolarHBondContact O-N 3.41Å; L372-Y377 VanDerWaalsContact O-N 3.12Å
373	A	86.9	Confident	82	Confident	1 Å²	1	23 Å²	23	1%	0.008	13%	0.13	C	C	.	.	I	π-helix	trans	-72.8	-41.2	-175.4	0	0	0	0	0	114.4	W52 P370 G371 P378	W52-A373 HydrophobicContact CB-CB 4.48Å; W52-A373 HydrophobicContact CD2-CB 4.16Å; W52-A373 HydrophobicContact CE3-CB 3.24Å; W52-A373 HydrophobicContact CH2-CB 4.44Å; W52-A373 HydrophobicContact CZ3-CB 3.4Å; P370-A373 PolarHBondContact O-N 3.48Å; P370-A373 VanDerWaalsContact O-N 3.17Å; G371-A373 VanDerWaalsContact C-N 3.32Å; G371-A373 PolarHBondContact O-N 3.23Å; A373-P378 WeakPolarHBondContact O-CD 3.01Å
374	F	90.9	Very high	82.3	Confident	1 Å²	1	20.3 Å²	20.3	0%	0.004	11%	0.111	C	C	.	.	I	π-helix	trans	-113	-4.8	-168.1	-59.9	-68.4	0	0	0	114.1	W52 V127 I130 A131 Y134 W199 P370 F395	W52-F374 HydrophobicContact CH2-CE2 4.1Å; W52-F374 AromaticContact CZ3-CE2 3.95Å; W52-F374 HydrophobicContact CZ3-CE2 3.95Å; W52-F374 HydrophobicContact CZ3-CZ 4.21Å; V127-F374 HydrophobicContact CG1-CE2 4.35Å; V127-F374 HydrophobicContact CG1-CZ 4.3Å; I130-F374 HydrophobicContact CB-CE1 4.2Å; I130-F374 HydrophobicContact CB-CE2 4.49Å; I130-F374 HydrophobicContact CB-CZ 4.04Å; I130-F374 HydrophobicContact CG2-CD1 3.66Å; I130-F374 HydrophobicContact CG2-CD2 4.15Å; I130-F374 HydrophobicContact CG2-CE1 3.52Å; I130-F374 HydrophobicContact CG2-CE2 4.02Å; I130-F374 HydrophobicContact CG2-CG 3.99Å; I130-F374 HydrophobicContact CG2-CZ 3.71Å; A131-F374 HydrophobicContact CB-CE1 4.29Å; Y134-F374 AromaticContact CD2-CD1 3.82Å; Y134-F374 HydrophobicContact CD2-CD1 3.82Å; Y134-F374 HydrophobicContact CD2-CE1 4.39Å; Y134-F374 HydrophobicContact CE2-CB 4.18Å; Y134-F374 AromaticContact CE2-CD1 3.9Å; Y134-F374 HydrophobicContact CE2-CD1 3.9Å; Y134-F374 HydrophobicContact CE2-CG 4.39Å; Y134-F374 HydrophobicContact CG-CD1 4.46Å; Y134-F374 PolarHBondContact OH-O 2.89Å; W199-F374 HydrophobicContact CD2-CB 4.32Å; W199-F374 HydrophobicContact CE3-CB 3.7Å; W199-F374 HydrophobicContact CE3-CG 4.46Å; W199-F374 HydrophobicContact CH2-CB 3.94Å; W199-F374 AromaticContact CH2-CD2 3.82Å; W199-F374 HydrophobicContact CH2-CD2 3.82Å; W199-F374 HydrophobicContact CH2-CG 4.01Å; W199-F374 HydrophobicContact CZ3-CB 3.48Å; W199-F374 VanDerWaalsContact CZ3-CB 3.48Å; W199-F374 HydrophobicContact CZ3-CD1 4.44Å; W199-F374 HydrophobicContact CZ3-CD2 4.06Å; W199-F374 AromaticContact CZ3-CG 3.76Å; W199-F374 HydrophobicContact CZ3-CG 3.76Å; P370-F374 HydrophobicContact CB-CD2 4.06Å; P370-F374 HydrophobicContact CB-CE2 4.46Å; P370-F374 VanDerWaalsContact O-CD2 3.32Å; P370-F374 WeakPolarHBondContact O-CD2 3.34Å; P370-F374 PolarHBondContact O-N 3.18Å; F374-F395 AromaticContact CD1-CE1 3.85Å; F374-F395 HydrophobicContact CD1-CE1 3.85Å; F374-F395 HydrophobicContact CE1-CD1 4.49Å; F374-F395 HydrophobicContact CE1-CE1 4.05Å
375	V	89.4	Confident	82.6	Confident	10 Å²	10	17.4 Å²	17.4	6%	0.061	10%	0.104	C	C	.	.	I	π-helix	trans	-119.4	-62.5	174.3	-178	0	0	0	0	110.9	S195 E196 W199 G371 P378 E379	S195-V375 WeakPolarHBondContact CB-O 3.27Å; E196-V375 HydrophobicContact CB-CG1 3.76Å; E196-V375 HydrophobicContact CG-CG1 4.31Å; W199-V375 HydrophobicContact CB-CG2 3.71Å; W199-V375 HydrophobicContact CD2-CG2 4.41Å; W199-V375 HydrophobicContact CG-CG2 3.73Å; G371-V375 WeakPolarHBondContact O-CA 3.4Å; G371-V375 WeakPolarHBondContact O-CB 3.38Å; G371-V375 PolarHBondContact O-N 2.96Å; V375-P378 WeakPolarHBondContact O-CD 3.47Å; V375-E379 VanDerWaalsContact O-CB 3.28Å; V375-E379 WeakPolarHBondContact O-CB 3.19Å; V375-E379 PolarHBondContact O-N 3.42Å; V375-E379 VanDerWaalsContact O-N 3.14Å
376	A	88.1	Confident	83.2	Confident	5 Å²	5	22.5 Å²	22.5	4%	0.041	13%	0.13	C	C	.	.	I	π-helix	trans	-67.7	-45.7	-172.9	0	0	0	0	0	113.4	L351 G371 L372 A380	L351-A376 HydrophobicContact CD2-CB 4.36Å; G371-A376 PolarHBondContact O-N 2.94Å; G371-A376 VanDerWaalsContact O-N 3.08Å; L372-A376 HydrophobicContact CD1-CB 4.09Å; A376-A380 WeakPolarHBondContact O-CB 3.49Å; A376-A380 PolarHBondContact O-N 3.5Å
377	Y	87.4	Confident	84.2	Confident	2 Å²	2	23.2 Å²	23.2	1%	0.008	14%	0.135	C	C	.	.	H	α-helix	trans	-65.3	-50.7	175.4	-70.8	-66.7	0	0	0	113.3	I347 L372 E379 A380 L381 F394	I347-Y377 HydrophobicContact CB-CE1 4.31Å; I347-Y377 WeakPolarHBondContact CB-OH 3.07Å; I347-Y377 HydrophobicContact CD1-CE1 3.54Å; I347-Y377 HydrophobicContact CD1-CE2 4.12Å; I347-Y377 WeakPolarHBondContact CD1-OH 3.29Å; I347-Y377 HydrophobicContact CG1-CE1 4.16Å; I347-Y377 WeakPolarHBondContact CG1-OH 3.5Å; I347-Y377 HydrophobicContact CG2-CE1 4.41Å; I347-Y377 WeakPolarHBondContact CG2-OH 3.08Å; L372-Y377 HydrophobicContact CD1-CE2 4.44Å; L372-Y377 HydrophobicContact CD2-CE2 4.36Å; L372-Y377 HydrophobicContact CG-CE2 3.8Å; L372-Y377 WeakPolarHBondContact O-CD2 3.35Å; L372-Y377 WeakPolarHBondContact O-CE2 3.26Å; L372-Y377 PolarHBondContact O-N 3.41Å; L372-Y377 VanDerWaalsContact O-N 3.12Å; Y377-E379 PolarHBondContact O-N 3.28Å; Y377-A380 PolarHBondContact O-N 3.35Å; Y377-L381 WeakPolarHBondContact O-CB 3.32Å; Y377-L381 VanDerWaalsContact O-CG 3.23Å; Y377-L381 WeakPolarHBondContact O-CG 3.29Å; Y377-L381 PolarHBondContact O-N 3.17Å; Y377-F394 HydrophobicContact CD1-CE2 4.31Å; Y377-F394 HydrophobicContact CD1-CZ 4.33Å; Y377-F394 HydrophobicContact CD2-CE1 4.2Å; Y377-F394 HydrophobicContact CD2-CE2 4.08Å; Y377-F394 AromaticContact CD2-CZ 3.42Å; Y377-F394 HydrophobicContact CD2-CZ 3.42Å; Y377-F394 VanDerWaalsContact CD2-CZ 3.42Å; Y377-F394 HydrophobicContact CE2-CZ 4.19Å; Y377-F394 HydrophobicContact CG-CE1 4.14Å; Y377-F394 AromaticContact CG-CE2 3.96Å; Y377-F394 HydrophobicContact CG-CE2 3.96Å; Y377-F394 AromaticContact CG-CZ 3.54Å; Y377-F394 HydrophobicContact CG-CZ 3.54Å
378	P	90.5	Very high	85.5	Confident	0 Å²	0	21.6 Å²	21.6	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-57.4	-37.3	-176.9	-29.2	41.7	0	0	0	111	Y134 W145 A373 V375 L381 T382 F395	Y134-P378 HydrophobicContact CE1-CB 4.46Å; Y134-P378 HydrophobicContact CE1-CG 4.33Å; W145-P378 HydrophobicContact CD2-CB 4.38Å; W145-P378 HydrophobicContact CG-CB 4.38Å; W145-P378 HydrophobicContact CZ2-CB 4.31Å; W145-P378 PolarHBondContact NE1-O 2.84Å; W145-P378 VanDerWaalsContact NE1-O 3.14Å; A373-P378 WeakPolarHBondContact O-CD 3.01Å; V375-P378 WeakPolarHBondContact O-CD 3.47Å; P378-L381 PolarHBondContact O-N 3.42Å; P378-T382 WeakPolarHBondContact O-CG2 3.42Å; P378-T382 PolarHBondContact O-N 2.88Å; P378-F395 HydrophobicContact CB-CZ 4.26Å; P378-F395 HydrophobicContact CG-CE1 4.36Å; P378-F395 HydrophobicContact CG-CE2 4.26Å; P378-F395 HydrophobicContact CG-CZ 3.5Å; P378-F395 VanDerWaalsContact CG-CZ 3.5Å
379	E	88.7	Confident	86.8	Confident	21 Å²	21	22.2 Å²	22.2	10%	0.098	13%	0.133	C	C	.	.	H	α-helix	trans	-61.6	-51.6	171.6	-169	176.8	167.6	0	0	112.6	V160 S193 S195 M354 V375 Y377 L381 T382	V160-E379 HydrophobicContact CG2-CG 4.23Å; S193-E379 VanDerWaalsContact CB-CD 3.46Å; S193-E379 WeakPolarHBondContact CB-OE1 3.43Å; S193-E379 WeakPolarHBondContact CB-OE2 2.94Å; S193-E379 PolarHBondContact OG-OE2 3.01Å; S195-E379 WeakPolarHBondContact OG-CA 3.41Å; S195-E379 VanDerWaalsContact OG-CB 3.24Å; S195-E379 WeakPolarHBondContact OG-CB 3.32Å; S195-E379 PolarHBondContact OG-N 3.33Å; M354-E379 HydrophobicContact CE-CB 3.46Å; M354-E379 VanDerWaalsContact CE-CB 3.46Å; M354-E379 VanDerWaalsContact CE-CD 3.46Å; M354-E379 HydrophobicContact CE-CG 3.29Å; V375-E379 VanDerWaalsContact O-CB 3.28Å; V375-E379 WeakPolarHBondContact O-CB 3.19Å; V375-E379 PolarHBondContact O-N 3.42Å; V375-E379 VanDerWaalsContact O-N 3.14Å; Y377-E379 PolarHBondContact O-N 3.28Å; E379-L381 PolarHBondContact O-N 3.1Å; E379-T382 WeakPolarHBondContact O-CB 3.36Å; E379-T382 PolarHBondContact O-N 3.13Å; E379-T382 PolarHBondContact O-OG1 3.02Å
380	A	88.3	Confident	87.9	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-61.7	-33.5	178.8	0	0	0	0	0	112.7	I350 M354 A376 Y377 T382 L383	I350-A380 HydrophobicContact CG2-CB 3.5Å; I350-A380 VanDerWaalsContact CG2-CB 3.5Å; M354-A380 HydrophobicContact CB-CB 4.2Å; M354-A380 HydrophobicContact CE-CB 3.88Å; M354-A380 VanDerWaalsContact CE-N 3.33Å; M354-A380 HydrophobicContact SD-CB 4.07Å; A376-A380 WeakPolarHBondContact O-CB 3.49Å; A376-A380 PolarHBondContact O-N 3.5Å; Y377-A380 PolarHBondContact O-N 3.35Å; A380-T382 VanDerWaalsContact C-N 3.32Å; A380-T382 PolarHBondContact O-N 2.66Å; A380-L383 WeakPolarHBondContact O-CB 3.43Å; A380-L383 PolarHBondContact O-N 3.38Å
381	L	90.8	Very high	88.9	Confident	1 Å²	1	22.1 Å²	22.1	1%	0.005	12%	0.123	C	C	.	.	H	α-helix	trans	-69.8	-27.3	176.6	-64.7	178.4	0	0	0	112.6	Y377 P378 E379 L383 L384 S387 W390 F394	Y377-L381 WeakPolarHBondContact O-CB 3.32Å; Y377-L381 VanDerWaalsContact O-CG 3.23Å; Y377-L381 WeakPolarHBondContact O-CG 3.29Å; Y377-L381 PolarHBondContact O-N 3.17Å; P378-L381 PolarHBondContact O-N 3.42Å; E379-L381 PolarHBondContact O-N 3.1Å; L381-L383 PolarHBondContact O-N 3.29Å; L381-L384 HydrophobicContact CD2-CD1 3.82Å; L381-L384 PolarHBondContact O-N 3.48Å; L381-S387 VanDerWaalsContact O-CB 3.32Å; L381-S387 WeakPolarHBondContact O-CB 3.12Å; L381-W390 HydrophobicContact CD2-CB 3.94Å; L381-F394 HydrophobicContact CD1-CB 3.74Å; L381-F394 HydrophobicContact CD1-CD1 4.01Å; L381-F394 HydrophobicContact CD1-CG 3.9Å
382	T	89.9	Confident	89.7	Confident	14 Å²	14	24 Å²	24	9%	0.086	13%	0.132	C	C	.	.	H	α-helix	trans	-64.1	-23.2	173.2	71.9	0	0	0	0	113	L143 T146 P378 E379 A380 L384 S387	L143-T382 HydrophobicContact CD1-CG2 4.18Å; T146-T382 WeakPolarHBondContact OG1-CG2 3.37Å; P378-T382 WeakPolarHBondContact O-CG2 3.42Å; P378-T382 PolarHBondContact O-N 2.88Å; E379-T382 WeakPolarHBondContact O-CB 3.36Å; E379-T382 PolarHBondContact O-N 3.13Å; E379-T382 PolarHBondContact O-OG1 3.02Å; A380-T382 VanDerWaalsContact C-N 3.32Å; A380-T382 PolarHBondContact O-N 2.66Å; T382-L384 VanDerWaalsContact C-N 3.31Å; T382-S387 PolarHBondContact O-OG 2.89Å
383	L	86.3	Confident	90.3	Very high	30 Å²	30	25.8 Å²	25.8	16%	0.157	14%	0.141	C	C	.	.	T	Hydrogen-bonded Turn	trans	-81.9	-12	-179.9	-52.9	-177.9	0	0	0	112.9	V160 F353 M354 A380 L381	V160-L383 HydrophobicContact CB-CD2 3.63Å; V160-L383 HydrophobicContact CG1-CD1 4.14Å; V160-L383 HydrophobicContact CG1-CD2 3.28Å; V160-L383 HydrophobicContact CG1-CG 4.33Å; V160-L383 HydrophobicContact CG2-CD2 4.1Å; F353-L383 HydrophobicContact CE1-CB 3.55Å; F353-L383 HydrophobicContact CE1-CD1 4.32Å; F353-L383 HydrophobicContact CZ-CB 4.08Å; M354-L383 HydrophobicContact CB-CD1 4.31Å; M354-L383 HydrophobicContact CG-CD1 4.33Å; A380-L383 WeakPolarHBondContact O-CB 3.43Å; A380-L383 PolarHBondContact O-N 3.38Å; L381-L383 PolarHBondContact O-N 3.29Å
384	L	87.7	Confident	90.6	Very high	3 Å²	3	26 Å²	26	2%	0.016	14%	0.141	C	C	.	.	S	Bend	trans	-83.9	145.1	177.8	-58.9	-179	0	0	0	110.7	R263 L267 F353 L381 T382 S387 W390	R263-L384 HydrophobicContact CG-CD1 4.5Å; L267-L384 HydrophobicContact CD1-CD2 3.5Å; L267-L384 VanDerWaalsContact CD1-CD2 3.5Å; L267-L384 HydrophobicContact CD2-CD2 3.66Å; L267-L384 HydrophobicContact CG-CD2 4.21Å; F353-L384 HydrophobicContact CD1-CD2 4.4Å; F353-L384 HydrophobicContact CE1-CD2 3.89Å; L381-L384 HydrophobicContact CD2-CD1 3.82Å; L381-L384 PolarHBondContact O-N 3.48Å; T382-L384 VanDerWaalsContact C-N 3.31Å; L384-S387 PolarHBondContact O-N 3.39Å; L384-S387 PolarHBondContact O-OG 3.17Å; L384-W390 HydrophobicContact CB-CG 4.27Å; L384-W390 HydrophobicContact CD1-CB 4.13Å; L384-W390 HydrophobicContact CD1-CD2 4.02Å; L384-W390 HydrophobicContact CD1-CG 3.77Å
385	P	86.3	Confident	90.9	Very high	78 Å²	78	25.9 Å²	25.9	51%	0.506	14%	0.141	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.6	141.1	170.8	28.8	-34.4	0	0	0	109.5	R263 S387 W390	R263-P385 VanDerWaalsContact NH2-CD 3.28Å; P385-S387 VanDerWaalsContact C-N 3.34Å; P385-W390 PolarHBondContact O-NE1 3.28Å
386	I	89.6	Confident	91.2	Very high	125 Å²	125	28.2 Å²	28.2	64%	0.641	15%	0.15	S	C	*	.	T	Hydrogen-bonded Turn	trans	58.8	47.6	-175.1	-42	170.3	0	0	0	110.3	P388 L389 W390	I386-P388 VanDerWaalsContact C-N 3.29Å; I386-P388 VanDerWaalsContact O-N 3.15Å; I386-L389 HydrophobicContact CG2-CB 3.84Å; I386-L389 WeakPolarHBondContact O-CB 3.21Å; I386-L389 PolarHBondContact O-N 3.27Å; I386-W390 VanDerWaalsContact O-CD1 3.25Å
387	S	90.8	Very high	91.5	Very high	22 Å²	22	28 Å²	28	15%	0.154	15%	0.149	C	C	.	.	H	α-helix	trans	-48	-40.4	-176.6	-33	0	0	0	0	114.6	L381 T382 L384 P385 L389 W390 S391	L381-S387 VanDerWaalsContact O-CB 3.32Å; L381-S387 WeakPolarHBondContact O-CB 3.12Å; T382-S387 PolarHBondContact O-OG 2.89Å; L384-S387 PolarHBondContact O-N 3.39Å; L384-S387 PolarHBondContact O-OG 3.17Å; P385-S387 VanDerWaalsContact C-N 3.34Å; S387-L389 VanDerWaalsContact C-N 3.3Å; S387-L389 PolarHBondContact O-N 2.62Å; S387-W390 PolarHBondContact O-N 3.26Å; S387-S391 PolarHBondContact O-N 3.19Å
388	P	93.4	Very high	91.9	Very high	23 Å²	23	28 Å²	28	15%	0.149	15%	0.149	C	C	.	.	H	α-helix	trans	-57.8	-37.6	178.1	-27.2	36.4	0	0	0	114.2	T140 L143 I386 S391 L392	T140-P388 VanDerWaalsContact O-CB 3.29Å; T140-P388 WeakPolarHBondContact O-CB 3.41Å; T140-P388 WeakPolarHBondContact O-CG 3.3Å; L143-P388 HydrophobicContact CD2-CB 4.4Å; L143-P388 HydrophobicContact CD2-CG 4.39Å; L143-P388 HydrophobicContact CG-CG 4.34Å; I386-P388 VanDerWaalsContact C-N 3.29Å; I386-P388 VanDerWaalsContact O-N 3.15Å; P388-S391 PolarHBondContact O-N 3.43Å; P388-L392 WeakPolarHBondContact O-CB 3.38Å; P388-L392 VanDerWaalsContact O-CG 3.31Å; P388-L392 WeakPolarHBondContact O-CG 3.09Å; P388-L392 PolarHBondContact O-N 3.11Å
389	L	93.4	Very high	92.1	Very high	84 Å²	84	28.1 Å²	28.1	44%	0.44	15%	0.149	S	C	.	.	H	α-helix	trans	-62.8	-48.2	179	175.7	64.5	0	0	0	111.4	I386 S387 S391 L392 L393	I386-L389 HydrophobicContact CG2-CB 3.84Å; I386-L389 WeakPolarHBondContact O-CB 3.21Å; I386-L389 PolarHBondContact O-N 3.27Å; S387-L389 VanDerWaalsContact C-N 3.3Å; S387-L389 PolarHBondContact O-N 2.62Å; L389-S391 VanDerWaalsContact C-N 3.32Å; L389-S391 PolarHBondContact O-N 3.19Å; L389-L392 PolarHBondContact O-N 3.22Å; L389-L393 HydrophobicContact CD1-CD1 4.3Å; L389-L393 HydrophobicContact CD1-CG 4.46Å; L389-L393 HydrophobicContact CG-CD1 4.31Å; L389-L393 WeakPolarHBondContact O-CG 3.35Å; L389-L393 PolarHBondContact O-N 3.36Å
390	W	93.6	Very high	92.5	Very high	36 Å²	36	27.4 Å²	27.4	14%	0.136	15%	0.146	C	C	.	.	H	α-helix	trans	-65.9	-38.7	-179.2	-55.4	103.4	0	0	0	111.6	I259 L260 R263 L381 L384 P385 I386 S387 L393 F394	I259-W390 HydrophobicContact CG2-CZ3 3.83Å; L260-W390 HydrophobicContact CD2-CE3 3.76Å; L260-W390 HydrophobicContact CD2-CZ3 4.31Å; R263-W390 HydrophobicContact CB-CH2 3.61Å; R263-W390 HydrophobicContact CB-CZ2 4.43Å; R263-W390 HydrophobicContact CB-CZ3 3.66Å; R263-W390 HydrophobicContact CG-CE3 4.36Å; R263-W390 HydrophobicContact CG-CH2 3.48Å; R263-W390 VanDerWaalsContact CG-CH2 3.48Å; R263-W390 HydrophobicContact CG-CZ2 3.8Å; R263-W390 HydrophobicContact CG-CZ3 3.77Å; L381-W390 HydrophobicContact CD2-CB 3.94Å; L384-W390 HydrophobicContact CB-CG 4.27Å; L384-W390 HydrophobicContact CD1-CB 4.13Å; L384-W390 HydrophobicContact CD1-CD2 4.02Å; L384-W390 HydrophobicContact CD1-CG 3.77Å; P385-W390 PolarHBondContact O-NE1 3.28Å; I386-W390 VanDerWaalsContact O-CD1 3.25Å; S387-W390 PolarHBondContact O-N 3.26Å; W390-L393 PolarHBondContact O-N 2.82Å; W390-F394 VanDerWaalsContact O-CB 3.28Å; W390-F394 WeakPolarHBondContact O-CB 3.47Å; W390-F394 PolarHBondContact O-N 3.24Å
391	S	94.2	Very high	92.8	Very high	0 Å²	0	28 Å²	28	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-64.5	-45.2	175.7	-174.1	0	0	0	0	112.5	S138 W145 S387 P388 L389 L393 F394 F395	S138-S391 PolarHBondContact OG-OG 2.85Å; W145-S391 WeakPolarHBondContact CZ2-OG 3.32Å; S387-S391 PolarHBondContact O-N 3.19Å; P388-S391 PolarHBondContact O-N 3.43Å; L389-S391 VanDerWaalsContact C-N 3.32Å; L389-S391 PolarHBondContact O-N 3.19Å; S391-L393 PolarHBondContact O-N 3.05Å; S391-F394 PolarHBondContact O-N 3.34Å; S391-F395 WeakPolarHBondContact O-CD2 3.27Å; S391-F395 PolarHBondContact O-N 3.44Å; S391-F395 WeakPolarHBondContact OG-CD2 3.35Å; S391-F395 VanDerWaalsContact OG-CE2 3.28Å; S391-F395 WeakPolarHBondContact OG-CE2 3.5Å
392	L	95.4	Very high	93	Very high	46 Å²	46	27.9 Å²	27.9	24%	0.241	15%	0.149	C	C	.	.	H	α-helix	trans	-58.7	-47.6	175.1	-77	168.7	0	0	0	111.7	F135 M139 P388 L389 F396	F135-L392 HydrophobicContact CD2-CD2 3.88Å; F135-L392 HydrophobicContact CE2-CD2 3.79Å; F135-L392 HydrophobicContact CZ-CD2 4.46Å; F135-L392 WeakPolarHBondContact O-CD2 3.49Å; M139-L392 HydrophobicContact CE-CD2 4.4Å; M139-L392 HydrophobicContact CG-CD2 3.78Å; P388-L392 WeakPolarHBondContact O-CB 3.38Å; P388-L392 VanDerWaalsContact O-CG 3.31Å; P388-L392 WeakPolarHBondContact O-CG 3.09Å; P388-L392 PolarHBondContact O-N 3.11Å; L389-L392 PolarHBondContact O-N 3.22Å; L392-F396 WeakPolarHBondContact O-CB 3.3Å; L392-F396 PolarHBondContact O-N 2.89Å
393	L	94.6	Very high	93.2	Very high	39 Å²	39	27.6 Å²	27.6	20%	0.204	15%	0.147	C	C	.	.	H	α-helix	trans	-62.1	-44.6	178.3	-70.8	174.3	0	0	0	111.8	V256 L389 W390 S391 M397	V256-L393 HydrophobicContact CG1-CB 4.12Å; L389-L393 HydrophobicContact CD1-CD1 4.3Å; L389-L393 HydrophobicContact CD1-CG 4.46Å; L389-L393 HydrophobicContact CG-CD1 4.31Å; L389-L393 WeakPolarHBondContact O-CG 3.35Å; L389-L393 PolarHBondContact O-N 3.36Å; W390-L393 PolarHBondContact O-N 2.82Å; S391-L393 PolarHBondContact O-N 3.05Å; L393-M397 WeakPolarHBondContact O-CB 3.28Å; L393-M397 PolarHBondContact O-N 3.07Å
394	F	94.3	Very high	93.5	Very high	5 Å²	5	26.4 Å²	26.4	2%	0.022	14%	0.142	C	C	.	.	H	α-helix	trans	-63.5	-51.1	-179.6	177.8	-102.5	0	0	0	112.3	L260 Y377 L381 W390 S391 F396 M397 L398	L260-F394 HydrophobicContact CD1-CD2 4.09Å; Y377-F394 HydrophobicContact CD1-CE2 4.31Å; Y377-F394 HydrophobicContact CD1-CZ 4.33Å; Y377-F394 HydrophobicContact CD2-CE1 4.2Å; Y377-F394 HydrophobicContact CD2-CE2 4.08Å; Y377-F394 AromaticContact CD2-CZ 3.42Å; Y377-F394 HydrophobicContact CD2-CZ 3.42Å; Y377-F394 VanDerWaalsContact CD2-CZ 3.42Å; Y377-F394 HydrophobicContact CE2-CZ 4.19Å; Y377-F394 HydrophobicContact CG-CE1 4.14Å; Y377-F394 AromaticContact CG-CE2 3.96Å; Y377-F394 HydrophobicContact CG-CE2 3.96Å; Y377-F394 AromaticContact CG-CZ 3.54Å; Y377-F394 HydrophobicContact CG-CZ 3.54Å; L381-F394 HydrophobicContact CD1-CB 3.74Å; L381-F394 HydrophobicContact CD1-CD1 4.01Å; L381-F394 HydrophobicContact CD1-CG 3.9Å; W390-F394 VanDerWaalsContact O-CB 3.28Å; W390-F394 WeakPolarHBondContact O-CB 3.47Å; W390-F394 PolarHBondContact O-N 3.24Å; S391-F394 PolarHBondContact O-N 3.34Å; F394-F396 PolarHBondContact O-N 3.02Å; F394-M397 HydrophobicContact CD2-CE 3.7Å; F394-M397 HydrophobicContact CE2-CE 3.86Å; F394-M397 WeakPolarHBondContact O-CB 3.5Å; F394-M397 PolarHBondContact O-N 2.86Å; F394-L398 HydrophobicContact CD1-CD1 4.16Å; F394-L398 HydrophobicContact CE1-CD1 3.5Å; F394-L398 VanDerWaalsContact CE1-CD1 3.5Å; F394-L398 HydrophobicContact CE1-CG 4.14Å; F394-L398 HydrophobicContact CZ-CD1 3.77Å; F394-L398 HydrophobicContact CZ-CD2 4.26Å; F394-L398 HydrophobicContact CZ-CG 4.15Å; F394-L398 PolarHBondContact O-N 3.29Å
395	F	95.9	Very high	93.8	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-70.1	-33.6	-179.7	-72	-62	0	0	0	112.7	Y134 F135 W145 F374 P378 S391 M397 L398 I399	Y134-F395 VanDerWaalsContact CB-CE1 3.48Å; Y134-F395 HydrophobicContact CD1-CE1 4.01Å; Y134-F395 AromaticContact CD1-CE2 3.61Å; Y134-F395 HydrophobicContact CD1-CE2 3.61Å; Y134-F395 AromaticContact CD1-CZ 3.23Å; Y134-F395 HydrophobicContact CD1-CZ 3.23Å; Y134-F395 HydrophobicContact CD2-CE1 4.37Å; Y134-F395 HydrophobicContact CD2-CZ 4.37Å; Y134-F395 HydrophobicContact CE1-CZ 4.05Å; Y134-F395 HydrophobicContact CG-CD1 4.36Å; Y134-F395 AromaticContact CG-CE1 3.71Å; Y134-F395 HydrophobicContact CG-CE1 3.71Å; Y134-F395 AromaticContact CG-CE2 3.91Å; Y134-F395 HydrophobicContact CG-CE2 3.91Å; Y134-F395 AromaticContact CG-CZ 3.42Å; Y134-F395 HydrophobicContact CG-CZ 3.42Å; Y134-F395 VanDerWaalsContact CG-CZ 3.42Å; F135-F395 HydrophobicContact CB-CB 4Å; W145-F395 HydrophobicContact CH2-CE2 4.26Å; W145-F395 HydrophobicContact CZ2-CE2 4.11Å; F374-F395 AromaticContact CD1-CE1 3.85Å; F374-F395 HydrophobicContact CD1-CE1 3.85Å; F374-F395 HydrophobicContact CE1-CD1 4.49Å; F374-F395 HydrophobicContact CE1-CE1 4.05Å; P378-F395 HydrophobicContact CB-CZ 4.26Å; P378-F395 HydrophobicContact CG-CE1 4.36Å; P378-F395 HydrophobicContact CG-CE2 4.26Å; P378-F395 HydrophobicContact CG-CZ 3.5Å; P378-F395 VanDerWaalsContact CG-CZ 3.5Å; S391-F395 WeakPolarHBondContact O-CD2 3.27Å; S391-F395 PolarHBondContact O-N 3.44Å; S391-F395 WeakPolarHBondContact OG-CD2 3.35Å; S391-F395 VanDerWaalsContact OG-CE2 3.28Å; S391-F395 WeakPolarHBondContact OG-CE2 3.5Å; F395-M397 VanDerWaalsContact C-N 3.35Å; F395-L398 HydrophobicContact CD1-CD1 4.03Å; F395-L398 HydrophobicContact CE1-CD1 4.34Å; F395-L398 PolarHBondContact O-N 3.38Å; F395-I399 VanDerWaalsContact O-CG1 3.31Å; F395-I399 WeakPolarHBondContact O-CG1 3.31Å; F395-I399 PolarHBondContact O-N 2.85Å
396	F	96	Very high	94.3	Very high	58 Å²	58	22.9 Å²	22.9	25%	0.254	12%	0.119	S	C	.	.	H	α-helix	trans	-63.5	-41.5	171.8	-172	-121.1	0	0	0	111.7	F135 F248 F252 L392 F394 I399 L400	F135-F396 HydrophobicContact CD2-CB 3.96Å; F135-F396 HydrophobicContact CE2-CB 3.8Å; F135-F396 HydrophobicContact CE2-CD2 4.06Å; F135-F396 HydrophobicContact CE2-CG 4.2Å; F135-F396 HydrophobicContact CZ-CD2 4.25Å; F248-F396 HydrophobicContact CE1-CE1 4.05Å; F248-F396 AromaticContact CE1-CZ 3.76Å; F248-F396 HydrophobicContact CE1-CZ 3.76Å; F248-F396 AromaticContact CZ-CE1 3.82Å; F248-F396 HydrophobicContact CZ-CE1 3.82Å; F248-F396 AromaticContact CZ-CZ 3.9Å; F248-F396 HydrophobicContact CZ-CZ 3.9Å; F252-F396 HydrophobicContact CD1-CD1 4.01Å; F252-F396 AromaticContact CD1-CE1 3.88Å; F252-F396 HydrophobicContact CD1-CE1 3.88Å; F252-F396 AromaticContact CE1-CD1 3.46Å; F252-F396 HydrophobicContact CE1-CD1 3.46Å; F252-F396 VanDerWaalsContact CE1-CD1 3.46Å; F252-F396 AromaticContact CE1-CE1 3.56Å; F252-F396 HydrophobicContact CE1-CE1 3.56Å; F252-F396 HydrophobicContact CZ-CD1 4.19Å; F252-F396 HydrophobicContact CZ-CE1 4.08Å; L392-F396 WeakPolarHBondContact O-CB 3.3Å; L392-F396 PolarHBondContact O-N 2.89Å; F394-F396 PolarHBondContact O-N 3.02Å; F396-I399 PolarHBondContact O-N 3.23Å; F396-L400 HydrophobicContact CD1-CD1 4.05Å; F396-L400 HydrophobicContact CE1-CD1 3.74Å; F396-L400 HydrophobicContact CE1-CG 4.46Å; F396-L400 HydrophobicContact CE2-CD2 4.42Å; F396-L400 HydrophobicContact CZ-CD1 4.06Å; F396-L400 HydrophobicContact CZ-CD2 4.26Å; F396-L400 HydrophobicContact CZ-CG 4.38Å; F396-L400 VanDerWaalsContact O-CG 3.31Å; F396-L400 WeakPolarHBondContact O-CG 3.21Å; F396-L400 PolarHBondContact O-N 3.46Å
397	M	95.1	Very high	94.5	Very high	1 Å²	1	17.3 Å²	17.3	1%	0.005	9%	0.09	C	C	.	.	H	α-helix	trans	-58.9	-45.9	171.2	173.3	-166.5	75.9	0	0	112	V51 P253 V256 L257 L393 F394 F395 I399 L400 L401	V51-M397 HydrophobicContact CG1-CE 4.44Å; P253-M397 HydrophobicContact CB-CG 3.93Å; V256-M397 HydrophobicContact CB-CB 4.01Å; V256-M397 HydrophobicContact CB-CG 4.25Å; V256-M397 HydrophobicContact CB-SD 4.07Å; V256-M397 HydrophobicContact CG1-CB 3.83Å; V256-M397 HydrophobicContact CG1-CG 4.28Å; V256-M397 HydrophobicContact CG1-SD 3.82Å; V256-M397 HydrophobicContact CG2-CB 4.26Å; L257-M397 HydrophobicContact CD2-CE 4.24Å; L257-M397 HydrophobicContact CD2-SD 3.62Å; L257-M397 HydrophobicContact CG-SD 3.69Å; L393-M397 WeakPolarHBondContact O-CB 3.28Å; L393-M397 PolarHBondContact O-N 3.07Å; F394-M397 HydrophobicContact CD2-CE 3.7Å; F394-M397 HydrophobicContact CE2-CE 3.86Å; F394-M397 WeakPolarHBondContact O-CB 3.5Å; F394-M397 PolarHBondContact O-N 2.86Å; F395-M397 VanDerWaalsContact C-N 3.35Å; M397-I399 VanDerWaalsContact C-N 3.33Å; M397-I399 PolarHBondContact O-N 3.23Å; M397-L400 PolarHBondContact O-N 2.94Å; M397-L401 HydrophobicContact CG-CD1 4.03Å; M397-L401 HydrophobicContact CG-CG 4.38Å; M397-L401 WeakPolarHBondContact O-CG 3.47Å; M397-L401 PolarHBondContact O-N 3Å
398	L	94.6	Very high	94.6	Very high	1 Å²	1	16.2 Å²	16.2	1%	0.005	8%	0.083	C	C	.	.	H	α-helix	trans	-60.6	-41.1	177.6	-67.5	-174.8	0	0	0	112	L48 V51 A131 F394 F395 L400 L401 G402	L48-L398 HydrophobicContact CD2-CB 3.92Å; L48-L398 HydrophobicContact CD2-CD2 3.68Å; L48-L398 HydrophobicContact CD2-CG 4.32Å; L48-L398 WeakPolarHBondContact CD2-O 3.3Å; V51-L398 HydrophobicContact CG1-CD2 4.33Å; A131-L398 HydrophobicContact CB-CB 4.16Å; F394-L398 HydrophobicContact CD1-CD1 4.16Å; F394-L398 HydrophobicContact CE1-CD1 3.5Å; F394-L398 VanDerWaalsContact CE1-CD1 3.5Å; F394-L398 HydrophobicContact CE1-CG 4.14Å; F394-L398 HydrophobicContact CZ-CD1 3.77Å; F394-L398 HydrophobicContact CZ-CD2 4.26Å; F394-L398 HydrophobicContact CZ-CG 4.15Å; F394-L398 PolarHBondContact O-N 3.29Å; F395-L398 HydrophobicContact CD1-CD1 4.03Å; F395-L398 HydrophobicContact CE1-CD1 4.34Å; F395-L398 PolarHBondContact O-N 3.38Å; L398-L400 PolarHBondContact O-N 3.01Å; L398-L401 PolarHBondContact O-N 3.01Å; L398-G402 PolarHBondContact O-N 3.04Å
399	I	96.3	Very high	94.7	Very high	3 Å²	3	15.1 Å²	15.1	2%	0.015	8%	0.076	C	C	.	.	H	α-helix	trans	-58	-49.4	174.5	-69.6	159.8	0	0	0	110.3	A131 F132 F135 F395 F396 M397 G402 L403	A131-I399 HydrophobicContact CB-CG1 3.79Å; F132-I399 HydrophobicContact CB-CD1 4.49Å; F132-I399 HydrophobicContact CD1-CD1 3.59Å; F132-I399 HydrophobicContact CD1-CG1 4.26Å; F132-I399 HydrophobicContact CD2-CD1 4.48Å; F132-I399 HydrophobicContact CD2-CG1 4.29Å; F132-I399 HydrophobicContact CD2-CG2 4.47Å; F132-I399 HydrophobicContact CE1-CD1 3.84Å; F132-I399 HydrophobicContact CE1-CG1 4.38Å; F132-I399 HydrophobicContact CE1-CG2 3.9Å; F132-I399 HydrophobicContact CE2-CG1 4.41Å; F132-I399 HydrophobicContact CE2-CG2 3.78Å; F132-I399 HydrophobicContact CG-CD1 3.94Å; F132-I399 HydrophobicContact CG-CG1 4.21Å; F132-I399 HydrophobicContact CZ-CD1 4.4Å; F132-I399 HydrophobicContact CZ-CG1 4.45Å; F132-I399 HydrophobicContact CZ-CG2 3.44Å; F132-I399 VanDerWaalsContact CZ-CG2 3.44Å; F135-I399 HydrophobicContact CB-CD1 3.77Å; F135-I399 HydrophobicContact CD1-CD1 4.37Å; F135-I399 HydrophobicContact CG-CD1 4Å; F395-I399 VanDerWaalsContact O-CG1 3.31Å; F395-I399 WeakPolarHBondContact O-CG1 3.31Å; F395-I399 PolarHBondContact O-N 2.85Å; F396-I399 PolarHBondContact O-N 3.23Å; M397-I399 VanDerWaalsContact C-N 3.33Å; M397-I399 PolarHBondContact O-N 3.23Å; I399-G402 PolarHBondContact O-N 2.82Å; I399-L403 HydrophobicContact CG2-CD1 3.75Å; I399-L403 HydrophobicContact CG2-CG 4.2Å; I399-L403 WeakPolarHBondContact O-CB 3.49Å; I399-L403 VanDerWaalsContact O-CG 3.25Å; I399-L403 WeakPolarHBondContact O-CG 3.4Å; I399-L403 PolarHBondContact O-N 3.47Å
400	L	95.7	Very high	94.8	Very high	7 Å²	7	11.3 Å²	11.3	4%	0.037	6%	0.055	C	C	.	.	H	α-helix	trans	-65.7	-41.7	-177.3	-63.8	174.5	0	0	0	112.9	F248 T249 F252 P253 F396 M397 L398 G402 L403 G404	F248-L400 HydrophobicContact CD1-CD2 4.12Å; F248-L400 HydrophobicContact CE1-CD1 3.89Å; F248-L400 HydrophobicContact CE1-CD2 3.85Å; F248-L400 HydrophobicContact CZ-CD1 4.39Å; T249-L400 HydrophobicContact CG2-CD2 3.84Å; F252-L400 HydrophobicContact CB-CD1 3.9Å; F252-L400 HydrophobicContact CD1-CD1 3.45Å; F252-L400 VanDerWaalsContact CD1-CD1 3.45Å; F252-L400 HydrophobicContact CE1-CD1 4.36Å; F252-L400 HydrophobicContact CG-CD1 4Å; P253-L400 HydrophobicContact CG-CB 3.93Å; F396-L400 HydrophobicContact CD1-CD1 4.05Å; F396-L400 HydrophobicContact CE1-CD1 3.74Å; F396-L400 HydrophobicContact CE1-CG 4.46Å; F396-L400 HydrophobicContact CE2-CD2 4.42Å; F396-L400 HydrophobicContact CZ-CD1 4.06Å; F396-L400 HydrophobicContact CZ-CD2 4.26Å; F396-L400 HydrophobicContact CZ-CG 4.38Å; F396-L400 VanDerWaalsContact O-CG 3.31Å; F396-L400 WeakPolarHBondContact O-CG 3.21Å; F396-L400 PolarHBondContact O-N 3.46Å; M397-L400 PolarHBondContact O-N 2.94Å; L398-L400 PolarHBondContact O-N 3.01Å; L400-G402 VanDerWaalsContact C-N 3.33Å; L400-L403 PolarHBondContact O-N 3Å; L400-G404 PolarHBondContact O-N 2.73Å; L400-G404 VanDerWaalsContact O-N 3.1Å
401	L	94.3	Very high	94.8	Very high	11 Å²	11	9.6 Å²	9.6	6%	0.058	5%	0.049	C	C	.	.	H	α-helix	trans	-61.8	-41.5	173.9	-71.8	177.1	0	0	0	111.6	V46 L48 V51 P253 M397 L398	V46-L401 HydrophobicContact CG1-CD2 3.84Å; L48-L401 HydrophobicContact CD2-CB 4.48Å; V51-L401 HydrophobicContact CG2-CD1 3.54Å; P253-L401 HydrophobicContact CB-CD1 4.47Å; P253-L401 HydrophobicContact CB-CD2 3.59Å; P253-L401 HydrophobicContact CB-CG 3.87Å; P253-L401 HydrophobicContact CG-CD2 3.77Å; P253-L401 HydrophobicContact CG-CG 3.96Å; M397-L401 HydrophobicContact CG-CD1 4.03Å; M397-L401 HydrophobicContact CG-CG 4.38Å; M397-L401 WeakPolarHBondContact O-CG 3.47Å; M397-L401 PolarHBondContact O-N 3Å; L398-L401 PolarHBondContact O-N 3.01Å
402	G	94.9	Very high	94.9	Very high	0 Å²	0	9.6 Å²	9.6	0%	0	5%	0.049	C	C	.	.	H	α-helix	trans	-65.2	-46.9	175.2	0	0	0	0	0	112.5	Y124 I128 L398 I399 L400 G404 T405 Q406	Y124-G402 WeakPolarHBondContact CE1-O 3.39Å; I128-G402 WeakPolarHBondContact CD1-O 3.43Å; L398-G402 PolarHBondContact O-N 3.04Å; I399-G402 PolarHBondContact O-N 2.82Å; L400-G402 VanDerWaalsContact C-N 3.33Å; G402-G404 VanDerWaalsContact C-N 3.26Å; G402-G404 PolarHBondContact O-N 3.3Å; G402-T405 PolarHBondContact O-N 3.12Å; G402-Q406 WeakPolarHBondContact O-CB 3.42Å; G402-Q406 PolarHBondContact O-N 3.36Å
403	L	94.9	Very high	94.9	Very high	7 Å²	7	8.2 Å²	8.2	4%	0.037	4%	0.042	C	C	.	.	H	α-helix	trans	-59.2	-37.7	180	-73.8	175.3	0	0	0	112.2	I128 V230 V231 I399 L400 T405 Q406 F407	I128-L403 HydrophobicContact CG2-CD2 4.45Å; V230-L403 HydrophobicContact CG1-CD1 3.82Å; V230-L403 HydrophobicContact CG1-CD2 4.04Å; V231-L403 HydrophobicContact CG2-CD2 3.58Å; I399-L403 HydrophobicContact CG2-CD1 3.75Å; I399-L403 HydrophobicContact CG2-CG 4.2Å; I399-L403 WeakPolarHBondContact O-CB 3.49Å; I399-L403 VanDerWaalsContact O-CG 3.25Å; I399-L403 WeakPolarHBondContact O-CG 3.4Å; I399-L403 PolarHBondContact O-N 3.47Å; L400-L403 PolarHBondContact O-N 3Å; L403-T405 PolarHBondContact O-N 2.96Å; L403-Q406 PolarHBondContact O-N 2.98Å; L403-F407 HydrophobicContact CB-CE1 3.94Å; L403-F407 HydrophobicContact CB-CE2 4.28Å; L403-F407 HydrophobicContact CB-CZ 3.7Å; L403-F407 HydrophobicContact CD1-CZ 4.49Å; L403-F407 HydrophobicContact CD2-CE1 3.99Å; L403-F407 HydrophobicContact CD2-CZ 4.39Å; L403-F407 HydrophobicContact CG-CE1 4.47Å; L403-F407 HydrophobicContact CG-CZ 4.41Å; L403-F407 WeakPolarHBondContact O-CD1 3.4Å; L403-F407 WeakPolarHBondContact O-CD2 3.29Å; L403-F407 WeakPolarHBondContact O-CG 3.41Å; L403-F407 PolarHBondContact O-N 2.93Å
404	G	92.7	Very high	94.9	Very high	6 Å²	6	6.3 Å²	6.3	6%	0.062	3%	0.032	C	C	.	.	H	α-helix	trans	-54	-52.8	176	0	0	0	0	0	113.3	G43 L400 G402	G43-G404 CarbonylContact O-C 3.54Å; G43-G404 WeakPolarHBondContact O-CA 3.41Å; L400-G404 PolarHBondContact O-N 2.73Å; L400-G404 VanDerWaalsContact O-N 3.1Å; G402-G404 VanDerWaalsContact C-N 3.26Å; G402-G404 PolarHBondContact O-N 3.3Å
405	T	94.5	Very high	94.8	Very high	6 Å²	6	6.1 Å²	6.1	4%	0.037	3%	0.031	C	C	.	.	H	α-helix	trans	-66.3	-42.3	176.5	-49.8	0	0	0	0	111.6	G43 Y44 Y124 W306 G402 L403 F407 C408 L409	G43-T405 PolarHBondContact O-N 2.85Å; G43-T405 VanDerWaalsContact O-N 3.13Å; Y44-T405 HydrophobicContact CD2-CG2 4.15Å; Y44-T405 HydrophobicContact CE2-CG2 4.35Å; Y44-T405 PolarHBondContact O-OG1 2.96Å; Y124-T405 HydrophobicContact CE1-CG2 4.13Å; Y124-T405 PolarHBondContact OH-OG1 3.48Å; W306-T405 HydrophobicContact CZ3-CG2 4.34Å; G402-T405 PolarHBondContact O-N 3.12Å; L403-T405 PolarHBondContact O-N 2.96Å; T405-F407 VanDerWaalsContact C-N 3.32Å; T405-F407 PolarHBondContact O-N 3.35Å; T405-C408 PolarHBondContact O-N 3.42Å; T405-C408 VanDerWaalsContact O-N 3.11Å; T405-L409 HydrophobicContact CG2-CD1 4.15Å; T405-L409 HydrophobicContact CG2-CG 4.45Å; T405-L409 PolarHBondContact O-N 2.93Å; T405-L409 VanDerWaalsContact O-N 3.17Å
406	Q	95.5	Very high	94.6	Very high	1 Å²	1	6.1 Å²	6.1	1%	0.005	3%	0.031	C	C	.	.	H	α-helix	trans	-63.9	-35.5	-175.9	-170	64.2	4.9	0	0	112.9	G121 I128 V231 G402 L403 C408 L409 L410	G121-Q406 PolarHBondContact O-NE2 3.46Å; G121-Q406 PolarHBondContact O-OE1 2.92Å; I128-Q406 HydrophobicContact CD1-CB 3.87Å; I128-Q406 HydrophobicContact CD1-CG 4.25Å; V231-Q406 HydrophobicContact CG1-CG 4.1Å; V231-Q406 HydrophobicContact CG2-CB 4.41Å; V231-Q406 HydrophobicContact CG2-CG 3.69Å; G402-Q406 WeakPolarHBondContact O-CB 3.42Å; G402-Q406 PolarHBondContact O-N 3.36Å; L403-Q406 PolarHBondContact O-N 2.98Å; Q406-C408 VanDerWaalsContact C-N 3.26Å; Q406-C408 PolarHBondContact O-N 2.97Å; Q406-L409 PolarHBondContact O-N 2.83Å; Q406-L410 PolarHBondContact O-N 2.96Å
407	F	94	Very high	94.5	Very high	7 Å²	7	6.2 Å²	6.2	3%	0.031	3%	0.034	C	C	.	.	H	α-helix	trans	-59.1	-40	175.1	-61.8	-19.8	0	0	0	111.7	V231 C234 L235 V245 T249 L403 T405 E411	V231-F407 HydrophobicContact CG1-CD1 4.46Å; C234-F407 HydrophobicContact CB-CD1 4.1Å; C234-F407 HydrophobicContact CB-CE1 3.38Å; C234-F407 HydrophobicContact CB-CE2 4.1Å; C234-F407 HydrophobicContact CB-CZ 3.38Å; C234-F407 WeakPolarHBondContact SG-CZ 3.38Å; L235-F407 HydrophobicContact CD1-CB 4.38Å; L235-F407 HydrophobicContact CD1-CD1 4.47Å; L235-F407 HydrophobicContact CD2-CB 4.44Å; L235-F407 HydrophobicContact CG-CD1 4.49Å; V245-F407 HydrophobicContact CG1-CE2 3.94Å; V245-F407 HydrophobicContact CG1-CZ 4.18Å; T249-F407 HydrophobicContact CG2-CE2 4.3Å; L403-F407 HydrophobicContact CB-CE1 3.94Å; L403-F407 HydrophobicContact CB-CE2 4.28Å; L403-F407 HydrophobicContact CB-CZ 3.7Å; L403-F407 HydrophobicContact CD1-CZ 4.49Å; L403-F407 HydrophobicContact CD2-CE1 3.99Å; L403-F407 HydrophobicContact CD2-CZ 4.39Å; L403-F407 HydrophobicContact CG-CE1 4.47Å; L403-F407 HydrophobicContact CG-CZ 4.41Å; L403-F407 WeakPolarHBondContact O-CD1 3.4Å; L403-F407 WeakPolarHBondContact O-CD2 3.29Å; L403-F407 WeakPolarHBondContact O-CG 3.41Å; L403-F407 PolarHBondContact O-N 2.93Å; T405-F407 VanDerWaalsContact C-N 3.32Å; T405-F407 PolarHBondContact O-N 3.35Å; F407-E411 VanDerWaalsContact O-CB 3.23Å; F407-E411 WeakPolarHBondContact O-CB 3.35Å; F407-E411 PolarHBondContact O-N 3.05Å
408	C	94.2	Very high	94.3	Very high	0 Å²	0	6.7 Å²	6.7	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-73	-39.5	-179.3	-174.6	0	0	0	0	113	Y44 G308 M312 T405 Q406 T412	Y44-C408 HydrophobicContact CD2-CB 3.25Å; Y44-C408 WeakPolarHBondContact CD2-SG 3.36Å; Y44-C408 HydrophobicContact CE2-CB 3.87Å; Y44-C408 VanDerWaalsContact CE2-SG 3.56Å; Y44-C408 HydrophobicContact CG-CB 3.81Å; G308-C408 VanDerWaalsContact CA-SG 3.55Å; M312-C408 HydrophobicContact CE-CB 3.66Å; M312-C408 WeakPolarHBondContact CE-SG 3.45Å; T405-C408 PolarHBondContact O-N 3.42Å; T405-C408 VanDerWaalsContact O-N 3.11Å; Q406-C408 VanDerWaalsContact C-N 3.26Å; Q406-C408 PolarHBondContact O-N 2.97Å; C408-T412 WeakPolarHBondContact O-CB 3.07Å; C408-T412 PolarHBondContact O-N 3.46Å; C408-T412 PolarHBondContact O-OG1 2.93Å
409	L	94.9	Very high	94	Very high	0 Å²	0	9.1 Å²	9.1	0%	0	5%	0.049	C	C	.	.	H	α-helix	trans	-62.3	-49.8	176.6	-68.3	174.4	0	0	0	111	I120 W306 T405 Q406 T412 L413	I120-L409 HydrophobicContact CB-CD1 4.24Å; I120-L409 HydrophobicContact CG2-CD1 3.62Å; I120-L409 HydrophobicContact CG2-CD2 4.48Å; W306-L409 HydrophobicContact CE3-CD2 3.76Å; W306-L409 HydrophobicContact CZ3-CD2 4.21Å; T405-L409 HydrophobicContact CG2-CD1 4.15Å; T405-L409 HydrophobicContact CG2-CG 4.45Å; T405-L409 PolarHBondContact O-N 2.93Å; T405-L409 VanDerWaalsContact O-N 3.17Å; Q406-L409 PolarHBondContact O-N 2.83Å; L409-T412 WeakPolarHBondContact O-CB 3.26Å; L409-T412 PolarHBondContact O-N 3.18Å; L409-L413 PolarHBondContact O-N 3Å
410	L	95.1	Very high	93.7	Very high	3 Å²	3	12.8 Å²	12.8	2%	0.016	7%	0.067	C	C	.	.	H	α-helix	trans	-64.3	-44.6	179.2	-175.3	61.4	0	0	0	111.7	W228 V231 L235 Q406 T412 L413 V414 T434 V437 A438	W228-L410 HydrophobicContact CZ3-CD1 4.25Å; W228-L410 HydrophobicContact CZ3-CD2 4.32Å; V231-L410 HydrophobicContact CG1-CB 4.45Å; V231-L410 HydrophobicContact CG1-CD2 3.57Å; L235-L410 HydrophobicContact CD1-CB 3.81Å; L235-L410 HydrophobicContact CD1-CD2 3.7Å; L235-L410 HydrophobicContact CD1-CG 3.98Å; Q406-L410 PolarHBondContact O-N 2.96Å; L410-T412 PolarHBondContact O-N 3.28Å; L410-L413 PolarHBondContact O-N 3.15Å; L410-V414 HydrophobicContact CD1-CG2 4.38Å; L410-V414 HydrophobicContact CG-CG2 4.36Å; L410-V414 WeakPolarHBondContact O-CG2 3.26Å; L410-V414 PolarHBondContact O-N 3.02Å; L410-T434 HydrophobicContact CD2-CG2 4.14Å; L410-V437 HydrophobicContact CD1-CB 3.93Å; L410-V437 HydrophobicContact CD1-CG1 3.35Å; L410-A438 HydrophobicContact CD2-CB 4.49Å
411	E	94.9	Very high	93.3	Very high	0 Å²	0	16.8 Å²	16.8	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-62.6	-32.5	178.4	-172.9	66.7	-176.4	0	0	111.8	L235 V239 T311 M312 Y315 F407 T415 K430	L235-E411 HydrophobicContact CD2-CB 4.35Å; V239-E411 HydrophobicContact CG1-CG 4.3Å; T311-E411 HydrophobicContact CG2-CG 4.48Å; M312-E411 HydrophobicContact CE-CB 3.92Å; M312-E411 HydrophobicContact CE-CG 4.08Å; Y315-E411 HydrophobicContact CE2-CG 4.47Å; Y315-E411 PolarHBondContact OH-OE1 3.17Å; F407-E411 VanDerWaalsContact O-CB 3.23Å; F407-E411 WeakPolarHBondContact O-CB 3.35Å; F407-E411 PolarHBondContact O-N 3.05Å; E411-T415 WeakPolarHBondContact O-CB 3.07Å; E411-T415 PolarHBondContact O-N 3.24Å; E411-T415 PolarHBondContact O-OG1 3.33Å; E411-K430 IonicContact OE1-NZ 2.87Å; E411-K430 PolarHBondContact OE1-NZ 3.2Å; E411-K430 IonicContact OE2-NZ 2.62Å
412	T	94.9	Very high	92.7	Very high	0 Å²	0	17.7 Å²	17.7	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-63.4	-45.5	174.6	-62.8	0	0	0	0	111.7	G308 C408 L409 L410 A416	G308-T412 VanDerWaalsContact CA-OG1 3.32Å; G308-T412 WeakPolarHBondContact CA-OG1 3.12Å; C408-T412 WeakPolarHBondContact O-CB 3.07Å; C408-T412 PolarHBondContact O-N 3.46Å; C408-T412 PolarHBondContact O-OG1 2.93Å; L409-T412 WeakPolarHBondContact O-CB 3.26Å; L409-T412 PolarHBondContact O-N 3.18Å; L410-T412 PolarHBondContact O-N 3.28Å; T412-A416 VanDerWaalsContact O-CB 3.26Å; T412-A416 WeakPolarHBondContact O-CB 3.27Å; T412-A416 PolarHBondContact O-N 2.87Å
413	L	95.1	Very high	92.2	Very high	17 Å²	17	21.4 Å²	21.4	9%	0.089	12%	0.122	C	C	.	.	H	α-helix	trans	-65.2	-47.7	176.5	-61.1	179.8	0	0	0	111.5	M114 T118 L409 L410 T415 A416 I417 V437	M114-L413 HydrophobicContact CG-CD2 3.62Å; M114-L413 WeakPolarHBondContact O-CD2 3.25Å; T118-L413 WeakPolarHBondContact OG1-CD2 3.46Å; L409-L413 PolarHBondContact O-N 3Å; L410-L413 PolarHBondContact O-N 3.15Å; L413-T415 VanDerWaalsContact C-N 3.34Å; L413-T415 PolarHBondContact O-N 3.13Å; L413-A416 PolarHBondContact O-N 3.17Å; L413-I417 VanDerWaalsContact O-CG1 3.32Å; L413-I417 WeakPolarHBondContact O-CG1 3.27Å; L413-I417 PolarHBondContact O-N 2.99Å; L413-V437 HydrophobicContact CB-CG1 4.22Å; L413-V437 HydrophobicContact CD1-CG1 4.21Å
414	V	94.3	Very high	91.6	Very high	0 Å²	0	26.4 Å²	26.4	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-59.9	-46.6	178.3	173.7	0	0	0	0	110.3	L410 A416 I417 V418 K430 V433 T434 V437	L410-V414 HydrophobicContact CD1-CG2 4.38Å; L410-V414 HydrophobicContact CG-CG2 4.36Å; L410-V414 WeakPolarHBondContact O-CG2 3.26Å; L410-V414 PolarHBondContact O-N 3.02Å; V414-A416 PolarHBondContact O-N 3.48Å; V414-I417 PolarHBondContact O-N 3.18Å; V414-V418 HydrophobicContact CG1-CG2 4.12Å; V414-V418 WeakPolarHBondContact O-CB 3.45Å; V414-V418 WeakPolarHBondContact O-CG2 3.38Å; V414-V418 PolarHBondContact O-N 3.39Å; V414-K430 HydrophobicContact CG1-CG 4.07Å; V414-V433 HydrophobicContact CG1-CG1 4.28Å; V414-T434 HydrophobicContact CG2-CG2 4.34Å; V414-V437 HydrophobicContact CG2-CB 4.35Å; V414-V437 HydrophobicContact CG2-CG2 4.21Å
415	T	92.8	Very high	91.3	Very high	1 Å²	1	33.6 Å²	33.6	1%	0.006	17%	0.174	C	C	.	.	H	α-helix	trans	-65.8	-39.7	-179.9	-56.5	0	0	0	0	111.8	R28 T311 Y315 E411 L413 I417 V418 D419	R28-T415 VanDerWaalsContact NH2-CG2 3.33Å; T311-T415 HydrophobicContact CG2-CG2 3.97Å; Y315-T415 PolarHBondContact OH-OG1 3.49Å; E411-T415 WeakPolarHBondContact O-CB 3.07Å; E411-T415 PolarHBondContact O-N 3.24Å; E411-T415 PolarHBondContact O-OG1 3.33Å; L413-T415 VanDerWaalsContact C-N 3.34Å; L413-T415 PolarHBondContact O-N 3.13Å; T415-I417 VanDerWaalsContact C-N 3.35Å; T415-I417 PolarHBondContact O-N 3.43Å; T415-V418 PolarHBondContact O-N 3.26Å; T415-D419 WeakPolarHBondContact O-CB 3.33Å; T415-D419 PolarHBondContact O-N 3.5Å
416	A	92.8	Very high	90.9	Very high	0 Å²	0	34.2 Å²	34.2	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-59.8	-44.8	175.6	0	0	0	0	0	111.8	L97 M114 T412 L413 V414 E420	L97-A416 HydrophobicContact CD1-CB 3.9Å; L97-A416 HydrophobicContact CG-CB 4.18Å; M114-A416 HydrophobicContact CG-CB 4.36Å; M114-A416 HydrophobicContact SD-CB 3.97Å; T412-A416 VanDerWaalsContact O-CB 3.26Å; T412-A416 WeakPolarHBondContact O-CB 3.27Å; T412-A416 PolarHBondContact O-N 2.87Å; L413-A416 PolarHBondContact O-N 3.17Å; V414-A416 PolarHBondContact O-N 3.48Å; A416-E420 VanDerWaalsContact O-CB 3.26Å; A416-E420 WeakPolarHBondContact O-CB 3.18Å; A416-E420 PolarHBondContact O-N 3.42Å; A416-E420 VanDerWaalsContact O-N 3.15Å
417	I	92.5	Very high	90.3	Very high	60 Å²	60	36.2 Å²	36.2	31%	0.308	19%	0.187	S	C	.	.	H	α-helix	trans	-67.2	-47.3	178.7	-66.1	166.5	0	0	0	111	L413 V414 T415 E420 I421 V433 V437	L413-I417 VanDerWaalsContact O-CG1 3.32Å; L413-I417 WeakPolarHBondContact O-CG1 3.27Å; L413-I417 PolarHBondContact O-N 2.99Å; V414-I417 PolarHBondContact O-N 3.18Å; T415-I417 VanDerWaalsContact C-N 3.35Å; T415-I417 PolarHBondContact O-N 3.43Å; I417-E420 PolarHBondContact O-N 3.28Å; I417-I421 HydrophobicContact CG2-CD1 3.73Å; I417-I421 WeakPolarHBondContact O-CG1 3.35Å; I417-I421 PolarHBondContact O-N 2.98Å; I417-I421 VanDerWaalsContact O-N 3.09Å; I417-V433 HydrophobicContact CG2-CG1 4.13Å; I417-V437 HydrophobicContact CD1-CG2 3.81Å
418	V	91.3	Very high	89.8	Confident	11 Å²	11	46.4 Å²	46.4	7%	0.067	23%	0.225	C	C	.	.	H	α-helix	trans	-64.1	-45.3	-178.4	172.3	0	0	0	0	111.2	V414 T415 G422 I426 I427 K430 V433	V414-V418 HydrophobicContact CG1-CG2 4.12Å; V414-V418 WeakPolarHBondContact O-CB 3.45Å; V414-V418 WeakPolarHBondContact O-CG2 3.38Å; V414-V418 PolarHBondContact O-N 3.39Å; T415-V418 PolarHBondContact O-N 3.26Å; V418-G422 WeakPolarHBondContact O-CA 3.4Å; V418-G422 PolarHBondContact O-N 3.38Å; V418-I426 HydrophobicContact CB-CG2 4.21Å; V418-I426 HydrophobicContact CG1-CG2 4.27Å; V418-I426 HydrophobicContact CG2-CG2 3.83Å; V418-I427 HydrophobicContact CG1-CG1 3.98Å; V418-K430 HydrophobicContact CG2-CG 4.38Å; V418-V433 HydrophobicContact CG2-CG1 4.33Å; V418-V433 HydrophobicContact CG2-CG2 4.44Å
419	D	88.6	Confident	89.5	Confident	51 Å²	51	48.9 Å²	48.9	27%	0.273	24%	0.239	S	C	.	.	H	α-helix	trans	-69.9	-32.3	-178.5	-78.6	-0.5	0	0	0	112.5	R28 G95 T415	R28-D419 IonicContact CZ-OD2 3.28Å; R28-D419 IonicContact NH1-OD1 3Å; R28-D419 IonicContact NH1-OD2 3.78Å; R28-D419 PolarHBondContact NH1-OD2 2.68Å; R28-D419 IonicContact NH2-OD2 2.64Å; R28-D419 PolarHBondContact NH2-OD2 2.83Å; R28-D419 VanDerWaalsContact NH2-OD2 3.08Å; G95-D419 PolarHBondContact N-OD2 3.06Å; T415-D419 WeakPolarHBondContact O-CB 3.33Å; T415-D419 PolarHBondContact O-N 3.5Å
420	E	89	Confident	89.2	Confident	80 Å²	80	50.8 Å²	50.8	37%	0.374	25%	0.247	S	C	.	.	H	α-helix	trans	-80.9	-42.4	-177.9	-170.8	66.2	-168.8	0	0	112.5	L97 K107 A416 I417	L97-E420 HydrophobicContact CD1-CB 4.24Å; L97-E420 HydrophobicContact CD1-CG 4.47Å; K107-E420 WeakPolarHBondContact CE-OE2 3.31Å; K107-E420 IonicContact NZ-OE1 3.51Å; K107-E420 PolarHBondContact NZ-OE1 3.17Å; K107-E420 IonicContact NZ-OE2 2.69Å; K107-E420 PolarHBondContact NZ-OE2 3.01Å; A416-E420 VanDerWaalsContact O-CB 3.26Å; A416-E420 WeakPolarHBondContact O-CB 3.18Å; A416-E420 PolarHBondContact O-N 3.42Å; A416-E420 VanDerWaalsContact O-N 3.15Å; I417-E420 PolarHBondContact O-N 3.28Å
421	I	88.2	Confident	89.1	Confident	92 Å²	92	53.5 Å²	53.5	47%	0.472	26%	0.264	S	S	.	.	H	α-helix	trans	-76.6	-35.9	178.3	-55.5	169.1	0	0	0	110.7	I417 T423 I426	I417-I421 HydrophobicContact CG2-CD1 3.73Å; I417-I421 WeakPolarHBondContact O-CG1 3.35Å; I417-I421 PolarHBondContact O-N 2.98Å; I417-I421 VanDerWaalsContact O-N 3.09Å; I421-T423 PolarHBondContact O-N 3.03Å; I421-T423 PolarHBondContact O-OG1 3.48Å; I421-I426 HydrophobicContact CB-CD1 3.63Å; I421-I426 HydrophobicContact CD1-CD1 3.54Å; I421-I426 HydrophobicContact CG1-CD1 4.18Å; I421-I426 HydrophobicContact CG2-CD1 3.33Å
422	G	81.4	Confident	89	Confident	30 Å²	30	56.9 Å²	56.9	31%	0.309	28%	0.284	S	S	.	.			trans	59.8	10.1	166.4	0	0	0	0	0	117	R27 V418	R27-G422 PolarHBondContact NH2-O 3.19Å; V418-G422 WeakPolarHBondContact O-CA 3.4Å; V418-G422 PolarHBondContact O-N 3.38Å
423	T	85.5	Confident	88.9	Confident	77 Å²	77	57.7 Å²	57.7	47%	0.472	29%	0.289	S	S	.	.			trans	-78	138.6	-179.6	-56.8	0	0	0	0	109.7	I421 W425 I426 I427	I421-T423 PolarHBondContact O-N 3.03Å; I421-T423 PolarHBondContact O-OG1 3.48Å; T423-W425 HydrophobicContact CG2-CB 4.28Å; T423-W425 PolarHBondContact O-N 3.25Å; T423-W425 VanDerWaalsContact O-N 3.11Å; T423-I426 PolarHBondContact O-N 2.84Å; T423-I427 PolarHBondContact O-N 3.07Å
424	D	82.5	Confident	88.9	Confident	112 Å²	112	57 Å²	57	60%	0.599	29%	0.285	S	S	*	.	H	α-helix	trans	-60	-28.7	-174.7	-63.9	-37.6	0	0	0	113.3	R27 R428	R27-D424 IonicContact CZ-OD1 3.92Å; R27-D424 IonicContact NE-OD1 2.66Å; R27-D424 IonicContact NH2-OD1 3.95Å; R27-D424 PolarHBondContact NH2-OD1 2.89Å; D424-R428 WeakPolarHBondContact O-CB 3.46Å; D424-R428 PolarHBondContact O-N 3.11Å
425	W	86.3	Confident	89	Confident	157 Å²	157	60.8 Å²	60.8	60%	0.595	31%	0.305	S	S	*	.	H	α-helix	trans	-60.9	-46.9	172.1	-178.1	90.2	0	0	0	112.6	T423 R428 N429	T423-W425 HydrophobicContact CG2-CB 4.28Å; T423-W425 PolarHBondContact O-N 3.25Å; T423-W425 VanDerWaalsContact O-N 3.11Å; W425-R428 PolarHBondContact O-N 2.95Å; W425-N429 VanDerWaalsContact CE2-ND2 3.26Å; W425-N429 PolarHBondContact NE1-ND2 3.27Å; W425-N429 VanDerWaalsContact NE1-ND2 3.12Å; W425-N429 VanDerWaalsContact O-CB 3.32Å; W425-N429 WeakPolarHBondContact O-CB 3.17Å; W425-N429 PolarHBondContact O-N 3.03Å
426	I	85.8	Confident	89.1	Confident	19 Å²	19	63.7 Å²	63.7	10%	0.097	33%	0.326	C	S	.	.	H	α-helix	trans	-66.7	-40.6	-178.6	-70.7	-171.4	0	0	0	110.9	V418 I421 T423 N429 K430 V433	V418-I426 HydrophobicContact CB-CG2 4.21Å; V418-I426 HydrophobicContact CG1-CG2 4.27Å; V418-I426 HydrophobicContact CG2-CG2 3.83Å; I421-I426 HydrophobicContact CB-CD1 3.63Å; I421-I426 HydrophobicContact CD1-CD1 3.54Å; I421-I426 HydrophobicContact CG1-CD1 4.18Å; I421-I426 HydrophobicContact CG2-CD1 3.33Å; T423-I426 PolarHBondContact O-N 2.84Å; I426-N429 CarbonylContact O-C 3.6Å; I426-N429 PolarHBondContact O-N 3.19Å; I426-K430 PolarHBondContact O-N 3.37Å; I426-K430 VanDerWaalsContact O-N 3.08Å; I426-V433 HydrophobicContact CG2-CG2 3.98Å
427	I	82.1	Confident	89.2	Confident	43 Å²	43	64.8 Å²	64.8	22%	0.221	33%	0.333	C	S	.	.	H	α-helix	trans	-65.4	-42.9	179.5	-63.5	169.9	0	0	0	110.2	R27 V418 T423	R27-I427 HydrophobicContact CG-CD1 4.38Å; R27-I427 HydrophobicContact CG-CG2 4.18Å; R27-I427 VanDerWaalsContact NH2-CD1 3.33Å; V418-I427 HydrophobicContact CG1-CG1 3.98Å; T423-I427 PolarHBondContact O-N 3.07Å
428	R	84.1	Confident	89.4	Confident	221 Å²	221	62.1 Å²	62.1	83%	0.834	32%	0.32	S	S	*	.	H	α-helix	trans	-69.9	-34.9	177.8	-167.9	173.1	-178	176	-0.2	112.6	D424 W425	D424-R428 WeakPolarHBondContact O-CB 3.46Å; D424-R428 PolarHBondContact O-N 3.11Å; W425-R428 PolarHBondContact O-N 2.95Å
429	N	88	Confident	89.6	Confident	53 Å²	53	65.1 Å²	65.1	28%	0.283	34%	0.337	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102.6	33.1	-178.4	-64.9	-14.7	0	0	0	112.8	W425 I426 T431 V432 V433	W425-N429 VanDerWaalsContact CE2-ND2 3.26Å; W425-N429 PolarHBondContact NE1-ND2 3.27Å; W425-N429 VanDerWaalsContact NE1-ND2 3.12Å; W425-N429 VanDerWaalsContact O-CB 3.32Å; W425-N429 WeakPolarHBondContact O-CB 3.17Å; W425-N429 PolarHBondContact O-N 3.03Å; I426-N429 CarbonylContact O-C 3.6Å; I426-N429 PolarHBondContact O-N 3.19Å; N429-T431 PolarHBondContact O-N 3.33Å; N429-T431 VanDerWaalsContact O-N 3.08Å; N429-V432 HydrophobicContact CB-CB 4.42Å; N429-V432 HydrophobicContact CB-CG2 4.21Å; N429-V432 WeakPolarHBondContact O-CB 3.4Å; N429-V432 PolarHBondContact O-N 2.91Å; N429-V433 PolarHBondContact O-N 3.25Å
430	K	89	Confident	90	Very high	39 Å²	39	66.5 Å²	66.5	17%	0.17	35%	0.348	C	S	.	.	H	α-helix	trans	-50.2	-37.8	179.9	180	173.3	173.9	173.8	0	112.9	Y315 E411 V414 V418 I426 V432 V433 T434	Y315-K430 PolarHBondContact OH-NZ 3.19Å; Y315-K430 VanDerWaalsContact OH-NZ 3.11Å; E411-K430 IonicContact OE1-NZ 2.87Å; E411-K430 PolarHBondContact OE1-NZ 3.2Å; E411-K430 IonicContact OE2-NZ 2.62Å; V414-K430 HydrophobicContact CG1-CG 4.07Å; V418-K430 HydrophobicContact CG2-CG 4.38Å; I426-K430 PolarHBondContact O-N 3.37Å; I426-K430 VanDerWaalsContact O-N 3.08Å; K430-V432 VanDerWaalsContact C-N 3.28Å; K430-V432 PolarHBondContact O-N 2.95Å; K430-V433 WeakPolarHBondContact O-CB 3.42Å; K430-V433 PolarHBondContact O-N 2.91Å; K430-V433 VanDerWaalsContact O-N 3.08Å; K430-T434 PolarHBondContact O-N 2.97Å; K430-T434 PolarHBondContact O-OG1 3.31Å
431	T	91.9	Very high	90.3	Very high	60 Å²	60	63 Å²	63	37%	0.368	33%	0.333	S	S	.	.	H	α-helix	trans	-59.1	-35.8	177.2	-51.3	0	0	0	0	113.1	F232 I236 N429 T434 L435	F232-T431 HydrophobicContact CE2-CG2 4.23Å; F232-T431 HydrophobicContact CZ-CG2 4.19Å; I236-T431 HydrophobicContact CG1-CG2 3.68Å; I236-T431 WeakPolarHBondContact O-CG2 3.34Å; I236-T431 PolarHBondContact O-OG1 3.44Å; N429-T431 PolarHBondContact O-N 3.33Å; N429-T431 VanDerWaalsContact O-N 3.08Å; T431-T434 PolarHBondContact O-N 3.11Å; T431-L435 PolarHBondContact O-N 3.14Å
432	V	92.9	Very high	90.7	Very high	71 Å²	71	61.1 Å²	61.1	43%	0.43	32%	0.321	S	S	.	.	H	α-helix	trans	-69	-37.5	176.5	180	0	0	0	0	110.6	N429 K430 L435 S436	N429-V432 HydrophobicContact CB-CB 4.42Å; N429-V432 HydrophobicContact CB-CG2 4.21Å; N429-V432 WeakPolarHBondContact O-CB 3.4Å; N429-V432 PolarHBondContact O-N 2.91Å; K430-V432 VanDerWaalsContact C-N 3.28Å; K430-V432 PolarHBondContact O-N 2.95Å; V432-L435 PolarHBondContact O-N 2.78Å; V432-S436 WeakPolarHBondContact O-CB 2.95Å; V432-S436 PolarHBondContact O-N 3.48Å; V432-S436 PolarHBondContact O-OG 3.49Å
433	V	93.7	Very high	91.5	Very high	18 Å²	18	64.7 Å²	64.7	11%	0.109	33%	0.333	C	S	.	.	H	α-helix	trans	-63.5	-47.8	173.9	-174.8	0	0	0	0	110	V414 I417 V418 I426 N429 K430 L435 S436 V437	V414-V433 HydrophobicContact CG1-CG1 4.28Å; I417-V433 HydrophobicContact CG2-CG1 4.13Å; V418-V433 HydrophobicContact CG2-CG1 4.33Å; V418-V433 HydrophobicContact CG2-CG2 4.44Å; I426-V433 HydrophobicContact CG2-CG2 3.98Å; N429-V433 PolarHBondContact O-N 3.25Å; K430-V433 WeakPolarHBondContact O-CB 3.42Å; K430-V433 PolarHBondContact O-N 2.91Å; K430-V433 VanDerWaalsContact O-N 3.08Å; V433-L435 VanDerWaalsContact C-N 3.32Å; V433-L435 PolarHBondContact O-N 3.04Å; V433-S436 PolarHBondContact O-N 3.43Å; V433-S436 VanDerWaalsContact O-N 3.14Å; V433-V437 HydrophobicContact CG1-CG2 4.35Å; V433-V437 WeakPolarHBondContact O-CG2 3.48Å; V433-V437 PolarHBondContact O-N 2.96Å
434	T	94.6	Very high	91.9	Very high	1 Å²	1	65.1 Å²	65.1	1%	0.006	33%	0.332	C	S	.	.	H	α-helix	trans	-57.3	-44.8	176.5	-52.8	0	0	0	0	111.7	F232 L235 L410 V414 K430 T431 V437 A438	F232-T434 HydrophobicContact CD2-CG2 4.18Å; L235-T434 HydrophobicContact CB-CG2 4.05Å; L410-T434 HydrophobicContact CD2-CG2 4.14Å; V414-T434 HydrophobicContact CG2-CG2 4.34Å; K430-T434 PolarHBondContact O-N 2.97Å; K430-T434 PolarHBondContact O-OG1 3.31Å; T431-T434 PolarHBondContact O-N 3.11Å; T434-V437 PolarHBondContact O-N 3.22Å; T434-A438 WeakPolarHBondContact O-CB 3.28Å; T434-A438 PolarHBondContact O-N 3.48Å
435	L	95.9	Very high	92.5	Very high	80 Å²	80	59.8 Å²	59.8	42%	0.419	30%	0.303	S	S	.	.	H	α-helix	trans	-61	-45.9	175.6	-178	61.5	0	0	0	111.4	F232 T431 V432 V433 V437 A438 V439	F232-L435 HydrophobicContact CD1-CD1 4.36Å; F232-L435 HydrophobicContact CD2-CB 4.08Å; F232-L435 HydrophobicContact CD2-CD1 4.03Å; F232-L435 HydrophobicContact CE1-CD1 4.25Å; F232-L435 HydrophobicContact CE2-CB 3.56Å; F232-L435 HydrophobicContact CE2-CD1 3.93Å; F232-L435 HydrophobicContact CE2-CG 4.29Å; F232-L435 HydrophobicContact CG-CD1 4.25Å; F232-L435 HydrophobicContact CZ-CB 4.15Å; F232-L435 HydrophobicContact CZ-CD1 4.04Å; T431-L435 PolarHBondContact O-N 3.14Å; V432-L435 PolarHBondContact O-N 2.78Å; V433-L435 VanDerWaalsContact C-N 3.32Å; V433-L435 PolarHBondContact O-N 3.04Å; L435-V437 PolarHBondContact O-N 2.93Å; L435-A438 PolarHBondContact O-N 3.4Å; L435-V439 HydrophobicContact CD1-CG2 4.26Å; L435-V439 HydrophobicContact CG-CG2 4.42Å; L435-V439 WeakPolarHBondContact O-CG2 3.39Å; L435-V439 PolarHBondContact O-N 3.41Å
436	S	95.1	Very high	93	Very high	62 Å²	62	54 Å²	54	43%	0.434	29%	0.285	S	S	.	.	H	α-helix	trans	-62	-44.9	-178.9	-56.7	0	0	0	0	111.5	V432 V433 A438 V439 V440	V432-S436 WeakPolarHBondContact O-CB 2.95Å; V432-S436 PolarHBondContact O-N 3.48Å; V432-S436 PolarHBondContact O-OG 3.49Å; V433-S436 PolarHBondContact O-N 3.43Å; V433-S436 VanDerWaalsContact O-N 3.14Å; S436-A438 VanDerWaalsContact C-N 3.34Å; S436-A438 PolarHBondContact O-N 2.93Å; S436-V439 PolarHBondContact O-N 3.5Å; S436-V440 WeakPolarHBondContact O-CG2 3.35Å; S436-V440 PolarHBondContact O-N 3.23Å
437	V	95.1	Very high	93.4	Very high	24 Å²	24	55.8 Å²	55.8	15%	0.145	30%	0.298	C	S	.	.	H	α-helix	trans	-65.4	-39	176.9	-178.3	0	0	0	0	110.9	L410 L413 V414 I417 V433 T434 L435 V440 G441	L410-V437 HydrophobicContact CD1-CB 3.93Å; L410-V437 HydrophobicContact CD1-CG1 3.35Å; L413-V437 HydrophobicContact CB-CG1 4.22Å; L413-V437 HydrophobicContact CD1-CG1 4.21Å; V414-V437 HydrophobicContact CG2-CB 4.35Å; V414-V437 HydrophobicContact CG2-CG2 4.21Å; I417-V437 HydrophobicContact CD1-CG2 3.81Å; V433-V437 HydrophobicContact CG1-CG2 4.35Å; V433-V437 WeakPolarHBondContact O-CG2 3.48Å; V433-V437 PolarHBondContact O-N 2.96Å; T434-V437 PolarHBondContact O-N 3.22Å; L435-V437 PolarHBondContact O-N 2.93Å; V437-V440 PolarHBondContact O-N 3.36Å; V437-G441 PolarHBondContact O-N 3.09Å
438	A	96.2	Very high	94	Very high	4 Å²	4	54.5 Å²	54.5	3%	0.033	29%	0.292	C	S	.	.	H	α-helix	trans	-64.9	-41	175.4	0	0	0	0	0	112.6	W228 F232 L410 T434 L435 S436 G441 F442	W228-A438 HydrophobicContact CE3-CB 3.85Å; W228-A438 HydrophobicContact CZ3-CB 4.29Å; F232-A438 HydrophobicContact CB-CB 4.4Å; L410-A438 HydrophobicContact CD2-CB 4.49Å; T434-A438 WeakPolarHBondContact O-CB 3.28Å; T434-A438 PolarHBondContact O-N 3.48Å; L435-A438 PolarHBondContact O-N 3.4Å; S436-A438 VanDerWaalsContact C-N 3.34Å; S436-A438 PolarHBondContact O-N 2.93Å; A438-G441 PolarHBondContact O-N 2.9Å; A438-F442 WeakPolarHBondContact O-CB 3.5Å; A438-F442 PolarHBondContact O-N 3.32Å
439	V	96.7	Very high	94.5	Very high	73 Å²	73	44.1 Å²	44.1	44%	0.442	25%	0.253	S	S	.	.	H	α-helix	trans	-65.1	-44.2	175.9	171	0	0	0	0	111	L435 S436 G441 F442 L443	L435-V439 HydrophobicContact CD1-CG2 4.26Å; L435-V439 HydrophobicContact CG-CG2 4.42Å; L435-V439 WeakPolarHBondContact O-CG2 3.39Å; L435-V439 PolarHBondContact O-N 3.41Å; S436-V439 PolarHBondContact O-N 3.5Å; V439-G441 VanDerWaalsContact C-N 3.34Å; V439-G441 PolarHBondContact O-N 2.8Å; V439-F442 WeakPolarHBondContact O-CB 3.48Å; V439-F442 PolarHBondContact O-N 3.49Å; V439-L443 HydrophobicContact CG1-CD1 4.32Å; V439-L443 WeakPolarHBondContact O-CG 3.43Å; V439-L443 PolarHBondContact O-N 2.59Å
440	V	96.4	Very high	94.8	Very high	80 Å²	80	42 Å²	42	49%	0.485	24%	0.242	S	C	.	.	H	α-helix	trans	-62.1	-43.7	174.8	172	0	0	0	0	110.6	S436 V437 F442 L443 L444	S436-V440 WeakPolarHBondContact O-CG2 3.35Å; S436-V440 PolarHBondContact O-N 3.23Å; V437-V440 PolarHBondContact O-N 3.36Å; V440-F442 VanDerWaalsContact C-N 3.32Å; V440-F442 PolarHBondContact O-N 3.29Å; V440-L443 PolarHBondContact O-N 3.05Å; V440-L444 HydrophobicContact CG1-CD1 3.84Å; V440-L444 HydrophobicContact CG1-CG 4.26Å; V440-L444 WeakPolarHBondContact O-CB 3.32Å; V440-L444 VanDerWaalsContact O-CG 3.31Å; V440-L444 WeakPolarHBondContact O-CG 3.5Å; V440-L444 PolarHBondContact O-N 3.07Å
441	G	95.7	Very high	95	Very high	6 Å²	6	41.5 Å²	41.5	6%	0.062	24%	0.24	C	C	.	.	H	α-helix	trans	-60.9	-37.7	175.4	0	0	0	0	0	113.2	W228 V437 A438 V439 G445	W228-G441 VanDerWaalsContact CE2-C 3.43Å; W228-G441 VanDerWaalsContact CZ2-C 3.44Å; W228-G441 PolarHBondContact NE1-O 2.83Å; V437-G441 PolarHBondContact O-N 3.09Å; A438-G441 PolarHBondContact O-N 2.9Å; V439-G441 VanDerWaalsContact C-N 3.34Å; V439-G441 PolarHBondContact O-N 2.8Å; G441-G445 PolarHBondContact O-N 3.2Å
442	F	96.6	Very high	95.1	Very high	53 Å²	53	38.7 Å²	38.7	23%	0.232	22%	0.223	C	C	.	.	H	α-helix	trans	-62	-51.1	172.4	170.3	-100.2	0	0	0	111.5	L221 L224 A225 W228 A438 V439 V440 L444 G445 V446	L221-F442 HydrophobicContact CD1-CE2 4.14Å; L221-F442 HydrophobicContact CD1-CZ 3.98Å; L224-F442 HydrophobicContact CB-CE2 4.41Å; L224-F442 HydrophobicContact CD2-CD2 4.08Å; L224-F442 HydrophobicContact CD2-CE2 4.2Å; L224-F442 HydrophobicContact CG-CD2 3.95Å; L224-F442 HydrophobicContact CG-CE2 4.18Å; A225-F442 HydrophobicContact CB-CD2 4.43Å; A225-F442 HydrophobicContact CB-CE2 3.79Å; A225-F442 HydrophobicContact CB-CZ 4.38Å; W228-F442 HydrophobicContact CB-CB 4.44Å; W228-F442 AromaticContact CD1-CD2 3.98Å; W228-F442 HydrophobicContact CG-CB 4Å; A438-F442 WeakPolarHBondContact O-CB 3.5Å; A438-F442 PolarHBondContact O-N 3.32Å; V439-F442 WeakPolarHBondContact O-CB 3.48Å; V439-F442 PolarHBondContact O-N 3.49Å; V440-F442 VanDerWaalsContact C-N 3.32Å; V440-F442 PolarHBondContact O-N 3.29Å; F442-L444 VanDerWaalsContact C-N 3.34Å; F442-L444 PolarHBondContact O-N 3.29Å; F442-G445 WeakPolarHBondContact O-CA 3.31Å; F442-G445 PolarHBondContact O-N 3.36Å; F442-V446 HydrophobicContact CE1-CG2 4.36Å; F442-V446 HydrophobicContact CZ-CG2 4.4Å; F442-V446 WeakPolarHBondContact O-CG2 3.46Å; F442-V446 PolarHBondContact O-N 3.35Å
443	L	96.8	Very high	95.1	Very high	106 Å²	106	35.4 Å²	35.4	56%	0.555	20%	0.203	S	C	*	.	H	α-helix	trans	-60.9	-42	180	-67.1	174.5	0	0	0	112.2	V439 V440 G445 V446	V439-L443 HydrophobicContact CG1-CD1 4.32Å; V439-L443 WeakPolarHBondContact O-CG 3.43Å; V439-L443 PolarHBondContact O-N 2.59Å; V440-L443 PolarHBondContact O-N 3.05Å; L443-G445 VanDerWaalsContact C-N 3.25Å; L443-G445 PolarHBondContact O-N 3.08Å; L443-V446 PolarHBondContact O-N 3.06Å
444	L	95.5	Very high	95	Very high	85 Å²	85	34.7 Å²	34.7	45%	0.445	20%	0.199	S	C	.	.	H	α-helix	trans	-69.7	-21.9	175.9	-66.5	176.5	0	0	0	113	I122 V440 F442 P447	I122-L444 HydrophobicContact CD1-CB 3.82Å; I122-L444 HydrophobicContact CD1-CD1 3.74Å; I122-L444 HydrophobicContact CD1-CG 4.42Å; I122-L444 HydrophobicContact CG1-CB 4.15Å; I122-L444 HydrophobicContact CG2-CB 4.45Å; V440-L444 HydrophobicContact CG1-CD1 3.84Å; V440-L444 HydrophobicContact CG1-CG 4.26Å; V440-L444 WeakPolarHBondContact O-CB 3.32Å; V440-L444 VanDerWaalsContact O-CG 3.31Å; V440-L444 WeakPolarHBondContact O-CG 3.5Å; V440-L444 PolarHBondContact O-N 3.07Å; F442-L444 VanDerWaalsContact C-N 3.34Å; F442-L444 PolarHBondContact O-N 3.29Å; L444-P447 WeakPolarHBondContact O-CD 3.34Å
445	G	95.1	Very high	94.9	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-81.5	-20	175.1	0	0	0	0	0	114.3	G441 F442 L443 L448	G441-G445 PolarHBondContact O-N 3.2Å; F442-G445 WeakPolarHBondContact O-CA 3.31Å; F442-G445 PolarHBondContact O-N 3.36Å; L443-G445 VanDerWaalsContact C-N 3.25Å; L443-G445 PolarHBondContact O-N 3.08Å; G445-L448 WeakPolarHBondContact O-CB 3.36Å; G445-L448 PolarHBondContact O-N 3.18Å; G445-L448 VanDerWaalsContact O-N 3.07Å
446	V	95.4	Very high	94.8	Very high	37 Å²	37	33.3 Å²	33.3	22%	0.224	19%	0.188	C	C	.	.	G	3₁₀ helix	trans	-55.8	-45.6	-178.2	178.3	0	0	0	0	113.1	L221 F442 L443 L448 T449	L221-V446 HydrophobicContact CD1-CB 4.43Å; L221-V446 HydrophobicContact CD1-CG1 4.15Å; L221-V446 HydrophobicContact CD1-CG2 3.84Å; F442-V446 HydrophobicContact CE1-CG2 4.36Å; F442-V446 HydrophobicContact CZ-CG2 4.4Å; F442-V446 WeakPolarHBondContact O-CG2 3.46Å; F442-V446 PolarHBondContact O-N 3.35Å; L443-V446 PolarHBondContact O-N 3.06Å; V446-L448 PolarHBondContact O-N 3.14Å; V446-L448 VanDerWaalsContact O-N 3.13Å; V446-T449 PolarHBondContact O-N 3.23Å; V446-T449 PolarHBondContact O-OG1 2.9Å
447	P	94.1	Very high	94.7	Very high	56 Å²	56	30.7 Å²	30.7	36%	0.364	17%	0.169	S	C	.	.	G	3₁₀ helix	trans	-58.7	-28.5	178.6	-24.2	35.1	0	0	0	113.6	F213 L444 T449 T450	F213-P447 HydrophobicContact CE1-CB 4.17Å; L444-P447 WeakPolarHBondContact O-CD 3.34Å; P447-T449 PolarHBondContact O-N 2.89Å; P447-T450 WeakPolarHBondContact O-CB 3.47Å; P447-T450 VanDerWaalsContact O-CG2 3.3Å; P447-T450 WeakPolarHBondContact O-CG2 3.13Å; P447-T450 PolarHBondContact O-N 3.37Å; P447-T450 PolarHBondContact O-OG1 3.12Å
448	L	94.5	Very high	94.5	Very high	16 Å²	16	30.4 Å²	30.4	8%	0.084	17%	0.167	C	C	.	.	G	3₁₀ helix	trans	-79.1	-5.3	178.2	-73.5	77.1	0	0	0	113.2	I122 V126 G445 V446 G453 W456 L457 M460	I122-L448 HydrophobicContact CG2-CD1 4.39Å; V126-L448 HydrophobicContact CB-CB 4.48Å; V126-L448 HydrophobicContact CG1-CB 4.17Å; V126-L448 HydrophobicContact CG2-CB 3.77Å; V126-L448 HydrophobicContact CG2-CD2 4Å; V126-L448 HydrophobicContact CG2-CG 4.5Å; G445-L448 WeakPolarHBondContact O-CB 3.36Å; G445-L448 PolarHBondContact O-N 3.18Å; G445-L448 VanDerWaalsContact O-N 3.07Å; V446-L448 PolarHBondContact O-N 3.14Å; V446-L448 VanDerWaalsContact O-N 3.13Å; L448-G453 VanDerWaalsContact O-CA 3.27Å; L448-G453 WeakPolarHBondContact O-CA 3.46Å; L448-W456 HydrophobicContact CG-CB 4.34Å; L448-L457 HydrophobicContact CD2-CB 4.3Å; L448-M460 HydrophobicContact CD1-SD 4.15Å; L448-M460 HydrophobicContact CD2-SD 3.88Å; L448-M460 HydrophobicContact CG-SD 4.48Å
449	T	95.1	Very high	94.3	Very high	2 Å²	2	30.2 Å²	30.2	1%	0.012	17%	0.165	C	C	.	.	G	3₁₀ helix	trans	-97.8	4.7	174.4	67.4	0	0	0	0	113.3	R217 I220 L224 V446 P447	R217-T449 WeakPolarHBondContact CB-O 3.37Å; R217-T449 PolarHBondContact N-O 2.69Å; I220-T449 HydrophobicContact CG2-CG2 3.88Å; L224-T449 HydrophobicContact CB-CG2 4.29Å; L224-T449 HydrophobicContact CD2-CG2 3.69Å; V446-T449 PolarHBondContact O-N 3.23Å; V446-T449 PolarHBondContact O-OG1 2.9Å; P447-T449 PolarHBondContact O-N 2.89Å
450	T	95	Very high	94.1	Very high	10 Å²	10	27.5 Å²	27.5	6%	0.061	15%	0.148	C	C	.	.	B	Isolated β-bridge	trans	-78.2	173.8	175	65.3	0	0	0	0	111.5	F213 E215 V216 P447 A452 G453	F213-T450 HydrophobicContact CB-CG2 4.42Å; F213-T450 HydrophobicContact CD1-CG2 4.12Å; F213-T450 VanDerWaalsContact O-CB 3.27Å; F213-T450 WeakPolarHBondContact O-CB 3.44Å; E215-T450 WeakPolarHBondContact O-CA 3.31Å; V216-T450 HydrophobicContact CG2-CG2 3.92Å; P447-T450 WeakPolarHBondContact O-CB 3.47Å; P447-T450 VanDerWaalsContact O-CG2 3.3Å; P447-T450 WeakPolarHBondContact O-CG2 3.13Å; P447-T450 PolarHBondContact O-N 3.37Å; P447-T450 PolarHBondContact O-OG1 3.12Å; T450-A452 PolarHBondContact O-N 3.22Å; T450-G453 WeakPolarHBondContact O-CA 3.24Å; T450-G453 PolarHBondContact O-N 2.76Å; T450-G453 PolarHBondContact OG1-N 2.83Å
451	Q	93.9	Very high	93.7	Very high	28 Å²	28	25.9 Å²	25.9	13%	0.131	14%	0.136	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.8	-32.4	176.1	-67.9	176.5	-13.1	0	0	112.5	N205 S207 F213 E215 G453	N205-Q451 HydrophobicContact CB-CG 4.42Å; N205-Q451 PolarHBondContact ND2-NE2 2.71Å; N205-Q451 VanDerWaalsContact O-CB 3.23Å; N205-Q451 WeakPolarHBondContact O-CB 3.31Å; N205-Q451 WeakPolarHBondContact O-CG 3.44Å; S207-Q451 PolarHBondContact N-O 3.41Å; F213-Q451 PolarHBondContact O-N 3.24Å; E215-Q451 PolarHBondContact O-N 3.05Å; Q451-G453 PolarHBondContact O-N 3.07Å
452	A	93.3	Very high	93.3	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	15%	0.15	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.4	-0.3	171.3	0	0	0	0	0	113.8	S207 N212 T450 I454 Y455 W456	S207-A452 WeakPolarHBondContact OG-CA 3.43Å; S207-A452 WeakPolarHBondContact OG-CB 3.24Å; S207-A452 PolarHBondContact OG-N 2.86Å; N212-A452 WeakPolarHBondContact O-CB 3.07Å; T450-A452 PolarHBondContact O-N 3.22Å; A452-I454 VanDerWaalsContact C-N 3.28Å; A452-I454 PolarHBondContact O-N 3.37Å; A452-Y455 HydrophobicContact CB-CD2 4.44Å; A452-Y455 WeakPolarHBondContact O-CB 3.45Å; A452-Y455 PolarHBondContact O-N 3.18Å; A452-W456 PolarHBondContact O-N 3.08Å
453	G	92.9	Very high	92.8	Very high	2 Å²	2	26.3 Å²	26.3	2%	0.021	14%	0.139	C	C	.	.	H	α-helix	trans	-58.2	-35.8	-166.9	0	0	0	0	0	114.2	L448 T450 Q451 Y455 W456 L457	L448-G453 VanDerWaalsContact O-CA 3.27Å; L448-G453 WeakPolarHBondContact O-CA 3.46Å; T450-G453 WeakPolarHBondContact O-CA 3.24Å; T450-G453 PolarHBondContact O-N 2.76Å; T450-G453 PolarHBondContact OG1-N 2.83Å; Q451-G453 PolarHBondContact O-N 3.07Å; G453-Y455 VanDerWaalsContact C-N 3.35Å; G453-Y455 PolarHBondContact O-N 3.05Å; G453-W456 PolarHBondContact O-N 3.23Å; G453-L457 WeakPolarHBondContact O-CB 3.49Å; G453-L457 PolarHBondContact O-N 2.96Å
454	I	91.3	Very high	92.2	Very high	3 Å²	3	21.2 Å²	21.2	2%	0.015	11%	0.113	C	C	.	.	H	α-helix	trans	-65.4	-36.6	178	-168.7	58.7	0	0	0	112.5	W199 L204 I206 A452 L457 L458 Y533	W199-I454 HydrophobicContact CZ2-CD1 4Å; L204-I454 HydrophobicContact CD1-CB 3.85Å; L204-I454 HydrophobicContact CD1-CG1 4.12Å; L204-I454 HydrophobicContact CD1-CG2 3.91Å; L204-I454 HydrophobicContact CD2-CB 4.43Å; I206-I454 HydrophobicContact CD1-CG2 3.59Å; I206-I454 HydrophobicContact CG1-CG2 4.02Å; A452-I454 VanDerWaalsContact C-N 3.28Å; A452-I454 PolarHBondContact O-N 3.37Å; I454-L457 PolarHBondContact O-N 3.07Å; I454-L458 HydrophobicContact CD1-CD1 4.42Å; I454-L458 HydrophobicContact CD1-CG 4.36Å; I454-L458 HydrophobicContact CG1-CD1 4.12Å; I454-L458 HydrophobicContact CG1-CG 4.49Å; I454-L458 WeakPolarHBondContact O-CB 3.43Å; I454-L458 VanDerWaalsContact O-CG 3.3Å; I454-L458 WeakPolarHBondContact O-CG 3.37Å; I454-L458 PolarHBondContact O-N 3.39Å; I454-Y533 HydrophobicContact CG1-CE2 4.44Å; I454-Y533 HydrophobicContact CG2-CE1 4.35Å
455	Y	93.2	Very high	91.3	Very high	14 Å²	14	17.2 Å²	17.2	6%	0.055	9%	0.092	C	C	.	.	H	α-helix	trans	-65.9	-43.8	177.2	-62.9	-63.3	0	0	0	111	I206 S207 I210 A452 G453 L458 L459 Y533 Y536 Y538	I206-Y455 HydrophobicContact CD1-CE1 4.35Å; I206-Y455 HydrophobicContact CD1-CE2 3.91Å; I206-Y455 WeakPolarHBondContact CD1-OH 3.47Å; I206-Y455 HydrophobicContact CG1-CE2 3.76Å; S207-Y455 WeakPolarHBondContact O-CE2 3.31Å; S207-Y455 PolarHBondContact O-OH 3.28Å; I210-Y455 HydrophobicContact CB-CD2 4.49Å; I210-Y455 HydrophobicContact CB-CG 4.31Å; A452-Y455 HydrophobicContact CB-CD2 4.44Å; A452-Y455 WeakPolarHBondContact O-CB 3.45Å; A452-Y455 PolarHBondContact O-N 3.18Å; G453-Y455 VanDerWaalsContact C-N 3.35Å; G453-Y455 PolarHBondContact O-N 3.05Å; Y455-L458 PolarHBondContact O-N 3.48Å; Y455-L459 VanDerWaalsContact O-CB 3.31Å; Y455-L459 WeakPolarHBondContact O-CB 3.4Å; Y455-L459 PolarHBondContact O-N 2.76Å; Y455-Y533 HydrophobicContact CD1-CD1 4.22Å; Y455-Y533 AromaticContact CE1-CD1 3.67Å; Y455-Y533 HydrophobicContact CE1-CD1 3.67Å; Y455-Y533 HydrophobicContact CE1-CG 4.37Å; Y455-Y536 AromaticContact CD1-CD1 3.83Å; Y455-Y536 HydrophobicContact CD1-CD1 3.83Å; Y455-Y536 AromaticContact CD1-CE1 3.78Å; Y455-Y536 HydrophobicContact CD1-CE1 3.78Å; Y455-Y536 AromaticContact CE1-CD1 3.43Å; Y455-Y536 HydrophobicContact CE1-CD1 3.43Å; Y455-Y536 VanDerWaalsContact CE1-CD1 3.43Å; Y455-Y536 HydrophobicContact CE1-CD2 4.25Å; Y455-Y536 AromaticContact CE1-CE1 3.73Å; Y455-Y536 HydrophobicContact CE1-CE1 3.73Å; Y455-Y536 AromaticContact CE1-CG 3.69Å; Y455-Y536 HydrophobicContact CE1-CG 3.69Å; Y455-Y538 WeakPolarHBondContact CA-OH 3.24Å; Y455-Y538 HydrophobicContact CD1-CE1 4.47Å; Y455-Y538 PolarHBondContact O-OH 2.8Å
456	W	93.9	Very high	90.4	Very high	39 Å²	39	18.6 Å²	18.6	15%	0.148	10%	0.102	C	C	.	.	H	α-helix	trans	-64.7	-42.9	175.2	-74.5	101.5	0	0	0	112.1	I210 F213 L448 A452 G453 L458 L459 M460 W541 I545	I210-W456 HydrophobicContact CD1-CD2 4.08Å; I210-W456 HydrophobicContact CD1-CE3 4.43Å; I210-W456 HydrophobicContact CD1-CG 4.43Å; I210-W456 HydrophobicContact CD1-CZ2 4.36Å; I210-W456 HydrophobicContact CG1-CD2 4.11Å; I210-W456 HydrophobicContact CG1-CG 4.28Å; I210-W456 HydrophobicContact CG1-CZ2 4.08Å; I210-W456 PolarHBondContact O-NE1 2.93Å; I210-W456 VanDerWaalsContact O-NE1 3.14Å; F213-W456 AromaticContact CE1-CD1 3.76Å; F213-W456 AromaticContact CE1-CE2 3.9Å; F213-W456 HydrophobicContact CE1-CZ2 4.44Å; F213-W456 AromaticContact CE1-NE1 3.31Å; F213-W456 VanDerWaalsContact CE1-NE1 3.31Å; F213-W456 HydrophobicContact CE2-CZ2 4.21Å; F213-W456 AromaticContact CZ-CE2 3.52Å; F213-W456 AromaticContact CZ-CZ2 3.62Å; F213-W456 HydrophobicContact CZ-CZ2 3.62Å; F213-W456 AromaticContact CZ-NE1 3.29Å; F213-W456 VanDerWaalsContact CZ-NE1 3.29Å; L448-W456 HydrophobicContact CG-CB 4.34Å; A452-W456 PolarHBondContact O-N 3.08Å; G453-W456 PolarHBondContact O-N 3.23Å; W456-L458 PolarHBondContact O-N 2.91Å; W456-L459 HydrophobicContact CE3-CD2 4.06Å; W456-L459 HydrophobicContact CZ3-CD2 4.01Å; W456-L459 PolarHBondContact O-N 3.24Å; W456-M460 VanDerWaalsContact O-CG 3.27Å; W456-M460 WeakPolarHBondContact O-CG 3.48Å; W456-M460 PolarHBondContact O-N 3.45Å; W456-W541 HydrophobicContact CH2-CZ3 4.19Å; W456-W541 HydrophobicContact CZ2-CH2 4.29Å; W456-W541 HydrophobicContact CZ2-CZ3 4.31Å; W456-I545 HydrophobicContact CH2-CD1 4.03Å; W456-I545 HydrophobicContact CZ3-CG2 4.19Å
457	L	92.6	Very high	89.8	Confident	6 Å²	6	18.4 Å²	18.4	3%	0.031	10%	0.098	C	C	.	.	H	α-helix	trans	-57.8	-48.3	176.5	-174.7	157.4	0	0	0	111.3	V126 V127 L448 G453 I454 M460 D461	V126-L457 HydrophobicContact CB-CD1 4.32Å; V126-L457 HydrophobicContact CG1-CD1 3.93Å; V127-L457 HydrophobicContact CG2-CD1 3.88Å; V127-L457 HydrophobicContact CG2-CD2 4.37Å; L448-L457 HydrophobicContact CD2-CB 4.3Å; G453-L457 WeakPolarHBondContact O-CB 3.49Å; G453-L457 PolarHBondContact O-N 2.96Å; I454-L457 PolarHBondContact O-N 3.07Å; L457-M460 PolarHBondContact O-N 3.47Å; L457-D461 WeakPolarHBondContact O-CB 3.43Å; L457-D461 PolarHBondContact O-N 3.19Å
458	L	90.5	Very high	89.5	Confident	19 Å²	19	15.8 Å²	15.8	10%	0.099	8%	0.081	C	C	.	.	H	α-helix	trans	-69.7	-35.2	-179.9	-69.9	172.1	0	0	0	112.7	P370 I454 Y455 W456 N462 Y533	P370-L458 HydrophobicContact CG-CD2 4.19Å; I454-L458 HydrophobicContact CD1-CD1 4.42Å; I454-L458 HydrophobicContact CD1-CG 4.36Å; I454-L458 HydrophobicContact CG1-CD1 4.12Å; I454-L458 HydrophobicContact CG1-CG 4.49Å; I454-L458 WeakPolarHBondContact O-CB 3.43Å; I454-L458 VanDerWaalsContact O-CG 3.3Å; I454-L458 WeakPolarHBondContact O-CG 3.37Å; I454-L458 PolarHBondContact O-N 3.39Å; Y455-L458 PolarHBondContact O-N 3.48Å; W456-L458 PolarHBondContact O-N 2.91Å; L458-N462 WeakPolarHBondContact O-CB 3.31Å; L458-N462 PolarHBondContact O-N 3.01Å; L458-N462 VanDerWaalsContact O-N 3.08Å; L458-N462 PolarHBondContact O-ND2 3.41Å; L458-Y533 HydrophobicContact CD1-CD2 3.15Å; L458-Y533 HydrophobicContact CD1-CE2 3.6Å; L458-Y533 HydrophobicContact CD1-CG 3.73Å
459	L	92.4	Very high	89.1	Confident	0 Å²	0	15.1 Å²	15.1	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-61.7	-46.7	172.3	-174.6	71.8	0	0	0	110.6	I210 Y455 W456 Y463 I531 Y538	I210-L459 HydrophobicContact CD1-CD2 4.04Å; Y455-L459 VanDerWaalsContact O-CB 3.31Å; Y455-L459 WeakPolarHBondContact O-CB 3.4Å; Y455-L459 PolarHBondContact O-N 2.76Å; W456-L459 HydrophobicContact CE3-CD2 4.06Å; W456-L459 HydrophobicContact CZ3-CD2 4.01Å; W456-L459 PolarHBondContact O-N 3.24Å; L459-Y463 HydrophobicContact CD1-CD2 3.78Å; L459-Y463 HydrophobicContact CD1-CE2 3.88Å; L459-Y463 HydrophobicContact CG-CD2 4.48Å; L459-Y463 WeakPolarHBondContact O-CD2 3.09Å; L459-Y463 PolarHBondContact O-N 3.28Å; L459-I531 HydrophobicContact CB-CD1 4.25Å; L459-I531 HydrophobicContact CD1-CD1 3.67Å; L459-Y538 HydrophobicContact CB-CE1 4.33Å; L459-Y538 HydrophobicContact CD1-CD1 4.42Å
460	M	92	Very high	88.7	Confident	15 Å²	15	15.4 Å²	15.4	7%	0.074	8%	0.079	C	C	.	.	H	α-helix	trans	-63.6	-47.4	176.7	-67.5	-172.5	68.6	0	0	111.8	Y119 I122 Y123 L448 W456 L457 N462 Y463 A464 M549	Y119-M460 HydrophobicContact CD1-CE 3.96Å; Y119-M460 HydrophobicContact CG-CE 4.36Å; I122-M460 HydrophobicContact CB-CE 4.4Å; I122-M460 HydrophobicContact CG2-CE 4.46Å; Y123-M460 HydrophobicContact CD1-CB 3.89Å; Y123-M460 HydrophobicContact CD1-CE 4.38Å; Y123-M460 HydrophobicContact CG-CB 4.27Å; L448-M460 HydrophobicContact CD1-SD 4.15Å; L448-M460 HydrophobicContact CD2-SD 3.88Å; L448-M460 HydrophobicContact CG-SD 4.48Å; W456-M460 VanDerWaalsContact O-CG 3.27Å; W456-M460 WeakPolarHBondContact O-CG 3.48Å; W456-M460 PolarHBondContact O-N 3.45Å; L457-M460 PolarHBondContact O-N 3.47Å; M460-N462 VanDerWaalsContact C-N 3.31Å; M460-N462 PolarHBondContact O-N 2.81Å; M460-Y463 PolarHBondContact O-N 3.39Å; M460-A464 WeakPolarHBondContact O-CB 3.21Å; M460-A464 PolarHBondContact O-N 2.72Å; M460-M549 HydrophobicContact CB-CE 4.22Å; M460-M549 HydrophobicContact CE-CE 3.8Å; M460-M549 HydrophobicContact CG-CE 3.62Å; M460-M549 HydrophobicContact CG-SD 4.15Å; M460-M549 HydrophobicContact SD-CE 4.33Å
461	D	87.9	Confident	88.5	Confident	46 Å²	46	16.9 Å²	16.9	25%	0.246	9%	0.086	C	C	.	.	H	α-helix	trans	-60.3	-40	-178.5	-174.4	52.4	0	0	0	112.3	Y123 Y300 L457	Y123-D461 HydrophobicContact CD2-CB 4.29Å; Y123-D461 HydrophobicContact CE2-CB 3.82Å; Y123-D461 WeakPolarHBondContact CE2-OD1 3Å; Y123-D461 VanDerWaalsContact CZ-OD1 3.27Å; Y123-D461 PolarHBondContact OH-OD1 3.31Å; Y300-D461 PolarHBondContact OH-O 2.85Å; L457-D461 WeakPolarHBondContact O-CB 3.43Å; L457-D461 PolarHBondContact O-N 3.19Å
462	N	86.7	Confident	88.4	Confident	65 Å²	65	15.5 Å²	15.5	35%	0.348	8%	0.08	S	C	.	.	H	α-helix	trans	-74.4	-44.4	179.7	-81.3	-81.2	0	0	0	113.1	L458 M460 S466 I531	L458-N462 WeakPolarHBondContact O-CB 3.31Å; L458-N462 PolarHBondContact O-N 3.01Å; L458-N462 VanDerWaalsContact O-N 3.08Å; L458-N462 PolarHBondContact O-ND2 3.41Å; M460-N462 VanDerWaalsContact C-N 3.31Å; M460-N462 PolarHBondContact O-N 2.81Å; N462-S466 WeakPolarHBondContact O-CB 3.3Å; N462-S466 PolarHBondContact O-OG 3.33Å; N462-I531 HydrophobicContact CB-CG2 3.65Å
463	Y	87.9	Confident	88.4	Confident	3 Å²	3	15.5 Å²	15.5	1%	0.012	8%	0.08	C	C	.	.	H	α-helix	trans	-99.8	-31.3	-170.1	-72.2	-91.3	0	0	0	115.1	L459 M460 A465 F467 Y528 I531 L543 G546 F547 A550	L459-Y463 HydrophobicContact CD1-CD2 3.78Å; L459-Y463 HydrophobicContact CD1-CE2 3.88Å; L459-Y463 HydrophobicContact CG-CD2 4.48Å; L459-Y463 WeakPolarHBondContact O-CD2 3.09Å; L459-Y463 PolarHBondContact O-N 3.28Å; M460-Y463 PolarHBondContact O-N 3.39Å; Y463-A465 PolarHBondContact O-N 3.02Å; Y463-F467 HydrophobicContact CD1-CE2 4.48Å; Y463-Y528 AromaticContact CE1-CE2 3.89Å; Y463-Y528 HydrophobicContact CE1-CE2 3.89Å; Y463-Y528 AromaticContact CZ-CE2 4Å; Y463-Y528 WeakPolarHBondContact OH-CE2 3.43Å; Y463-Y528 PolarHBondContact OH-OH 3.04Å; Y463-I531 HydrophobicContact CE2-CB 4.48Å; Y463-I531 HydrophobicContact CE2-CD1 3.97Å; Y463-I531 HydrophobicContact CE2-CG1 3.99Å; Y463-I531 HydrophobicContact CE2-CG2 3.67Å; Y463-L543 HydrophobicContact CE2-CD2 4.44Å; Y463-L543 WeakPolarHBondContact OH-CD2 3.31Å; Y463-G546 WeakPolarHBondContact CB-O 3.43Å; Y463-F547 HydrophobicContact CE1-CD1 4.41Å; Y463-F547 HydrophobicContact CE1-CD2 4.27Å; Y463-F547 HydrophobicContact CE1-CE1 4.22Å; Y463-F547 HydrophobicContact CE1-CE2 4.08Å; Y463-F547 HydrophobicContact CE1-CG 4.43Å; Y463-F547 HydrophobicContact CE1-CZ 4.06Å; Y463-A550 WeakPolarHBondContact O-CB 3.41Å
464	A	83.9	Confident	88.3	Confident	0 Å²	0	16 Å²	16	0%	0	8%	0.082	C	C	.	.	S	Bend	trans	-63.9	-31.5	-170	0	0	0	0	0	113.1	Y119 M460 M549	Y119-A464 HydrophobicContact CD2-CB 4.01Å; Y119-A464 HydrophobicContact CG-CB 4.09Å; M460-A464 WeakPolarHBondContact O-CB 3.21Å; M460-A464 PolarHBondContact O-N 2.72Å; A464-M549 HydrophobicContact CB-CE 4Å
465	A	76.4	Confident	88.4	Confident	0 Å²	0	17.8 Å²	17.8	0%	0	9%	0.091	C	C	.	.	S	Bend	trans	-121.5	-36.1	-171.2	0	0	0	0	0	113.5	V116 I120 Y300 Y463 F467 S468 L469	V116-A465 HydrophobicContact CG1-CB 3.96Å; I120-A465 HydrophobicContact CD1-CB 3.82Å; I120-A465 HydrophobicContact CG1-CB 4.09Å; Y300-A465 HydrophobicContact CE1-CB 3.87Å; Y300-A465 WeakPolarHBondContact OH-CB 3.45Å; Y463-A465 PolarHBondContact O-N 3.02Å; A465-F467 PolarHBondContact O-N 3.28Å; A465-S468 PolarHBondContact O-N 2.73Å; A465-L469 HydrophobicContact CB-CD1 3.7Å; A465-L469 HydrophobicContact CB-CG 4.16Å; A465-L469 WeakPolarHBondContact O-CB 3.32Å; A465-L469 WeakPolarHBondContact O-CD1 3.17Å; A465-L469 WeakPolarHBondContact O-CG 3.49Å; A465-L469 PolarHBondContact O-N 3.2Å
466	S	76.5	Confident	88.5	Confident	30 Å²	30	17.1 Å²	17.1	21%	0.21	9%	0.089	C	C	.	.	H	α-helix	trans	-55.7	-56.3	-168	-63.2	0	0	0	0	113.5	Y300 N462 V470	Y300-S466 VanDerWaalsContact OH-CA 3.31Å; Y300-S466 WeakPolarHBondContact OH-CA 3.35Å; Y300-S466 PolarHBondContact OH-N 3.1Å; Y300-S466 PolarHBondContact OH-OG 2.96Å; N462-S466 WeakPolarHBondContact O-CB 3.3Å; N462-S466 PolarHBondContact O-OG 3.33Å; S466-V470 WeakPolarHBondContact O-CG2 3.24Å
467	F	81.9	Confident	88.4	Confident	33 Å²	33	15.3 Å²	15.3	15%	0.145	8%	0.082	C	C	.	.	H	α-helix	trans	-74.1	-43.8	-178.4	-69.8	-81.4	0	0	0	111.9	Y463 A465 L469 V470 I471 T524 Y528 A550	Y463-F467 HydrophobicContact CD1-CE2 4.48Å; A465-F467 PolarHBondContact O-N 3.28Å; F467-L469 PolarHBondContact O-N 2.75Å; F467-V470 PolarHBondContact O-N 3.23Å; F467-I471 WeakPolarHBondContact O-CG1 3.3Å; F467-I471 PolarHBondContact O-N 2.89Å; F467-T524 HydrophobicContact CD1-CG2 3.95Å; F467-T524 HydrophobicContact CE1-CG2 3.54Å; F467-T524 HydrophobicContact CZ-CG2 4.05Å; F467-Y528 HydrophobicContact CE2-CD2 4.23Å; F467-Y528 HydrophobicContact CE2-CE2 4.46Å; F467-Y528 AromaticContact CZ-CD2 3.69Å; F467-Y528 HydrophobicContact CZ-CD2 3.69Å; F467-Y528 HydrophobicContact CZ-CE2 4.34Å; F467-Y528 HydrophobicContact CZ-CG 4.44Å; F467-A550 HydrophobicContact CB-CB 4.47Å
468	S	87.4	Confident	88.5	Confident	0 Å²	0	18.3 Å²	18.3	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-61.6	-43.5	-174.4	-53.1	0	0	0	0	112.5	A465 V470 I471 I472 A550 S553	A465-S468 PolarHBondContact O-N 2.73Å; S468-V470 PolarHBondContact O-N 3.34Å; S468-I471 PolarHBondContact O-N 2.94Å; S468-I472 WeakPolarHBondContact O-CB 3.48Å; S468-I472 WeakPolarHBondContact O-CG1 3.46Å; S468-I472 PolarHBondContact O-N 3.43Å; S468-A550 WeakPolarHBondContact OG-CA 3.44Å; S468-A550 PolarHBondContact OG-O 3.32Å; S468-S553 WeakPolarHBondContact CB-OG 3.41Å; S468-S553 PolarHBondContact OG-OG 2.96Å
469	L	86.4	Confident	88.6	Confident	3 Å²	3	17.4 Å²	17.4	2%	0.016	9%	0.093	C	C	.	.	H	α-helix	trans	-65.7	-41	-176.4	-72.3	174.7	0	0	0	112.9	V116 A305 W306 A465 F467 I471 I472 S473	V116-L469 HydrophobicContact CG1-CD2 3.77Å; V116-L469 HydrophobicContact CG1-CG 4.15Å; A305-L469 HydrophobicContact CB-CD2 4.44Å; A305-L469 WeakPolarHBondContact O-CD2 3.19Å; W306-L469 HydrophobicContact CG-CD2 4.2Å; W306-L469 HydrophobicContact CZ2-CD1 4.36Å; A465-L469 HydrophobicContact CB-CD1 3.7Å; A465-L469 HydrophobicContact CB-CG 4.16Å; A465-L469 WeakPolarHBondContact O-CB 3.32Å; A465-L469 WeakPolarHBondContact O-CD1 3.17Å; A465-L469 WeakPolarHBondContact O-CG 3.49Å; A465-L469 PolarHBondContact O-N 3.2Å; F467-L469 PolarHBondContact O-N 2.75Å; L469-I471 VanDerWaalsContact C-N 3.31Å; L469-I471 PolarHBondContact O-N 2.9Å; L469-I472 PolarHBondContact O-N 3.17Å; L469-S473 WeakPolarHBondContact O-CB 3.34Å; L469-S473 PolarHBondContact O-N 2.89Å
470	V	87.2	Confident	88.7	Confident	7 Å²	7	17.4 Å²	17.4	4%	0.042	9%	0.093	C	C	.	.	H	α-helix	trans	-64.8	-40.4	178.5	-176	0	0	0	0	110	S466 F467 S468 C474 I517 I520 L521	S466-V470 WeakPolarHBondContact O-CG2 3.24Å; F467-V470 PolarHBondContact O-N 3.23Å; S468-V470 PolarHBondContact O-N 3.34Å; V470-C474 WeakPolarHBondContact O-CB 3.32Å; V470-C474 PolarHBondContact O-N 3.26Å; V470-I517 HydrophobicContact CG1-CG2 3.85Å; V470-I517 WeakPolarHBondContact O-CG2 3.26Å; V470-I520 HydrophobicContact CG1-CB 4.47Å; V470-I520 HydrophobicContact CG1-CG2 4.16Å; V470-I520 HydrophobicContact CG2-CG2 4.31Å; V470-L521 HydrophobicContact CB-CD1 4.39Å; V470-L521 HydrophobicContact CG1-CB 3.76Å; V470-L521 HydrophobicContact CG1-CD1 4.16Å
471	I	90.3	Very high	88.8	Confident	41 Å²	41	16.7 Å²	16.7	21%	0.21	9%	0.089	C	C	.	.	H	α-helix	trans	-65.9	-50.1	176.4	-64.3	168.9	0	0	0	111.3	F467 S468 L469 S473 C474 I475 L521 V554	F467-I471 WeakPolarHBondContact O-CG1 3.3Å; F467-I471 PolarHBondContact O-N 2.89Å; S468-I471 PolarHBondContact O-N 2.94Å; L469-I471 VanDerWaalsContact C-N 3.31Å; L469-I471 PolarHBondContact O-N 2.9Å; I471-S473 VanDerWaalsContact C-N 3.3Å; I471-S473 PolarHBondContact O-N 3.27Å; I471-C474 PolarHBondContact O-N 3.13Å; I471-I475 HydrophobicContact CG2-CD1 3.72Å; I471-I475 HydrophobicContact CG2-CG1 4.5Å; I471-I475 WeakPolarHBondContact O-CG1 3.41Å; I471-I475 PolarHBondContact O-N 3.32Å; I471-L521 HydrophobicContact CD1-CD1 4.16Å; I471-L521 HydrophobicContact CG1-CD1 3.46Å; I471-L521 VanDerWaalsContact CG1-CD1 3.46Å; I471-L521 HydrophobicContact CG1-CD2 4.04Å; I471-L521 HydrophobicContact CG1-CG 4.42Å; I471-V554 HydrophobicContact CB-CG2 4.32Å; I471-V554 HydrophobicContact CD1-CG1 4.35Å; I471-V554 HydrophobicContact CD1-CG2 3.98Å; I471-V554 HydrophobicContact CG2-CG1 3.86Å; I471-V554 HydrophobicContact CG2-CG2 4.28Å
472	I	92.6	Very high	89.1	Confident	0 Å²	0	20.5 Å²	20.5	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-57.6	-45.7	178.2	-72.5	169.6	0	0	0	110	V109 M113 V116 A305 S468 L469 I475 M476 I557	V109-I472 HydrophobicContact CG1-CG2 3.7Å; M113-I472 HydrophobicContact CE-CG2 3.78Å; M113-I472 HydrophobicContact CG-CG2 3.82Å; V116-I472 HydrophobicContact CG2-CD1 4.09Å; A305-I472 HydrophobicContact CB-CG2 4.04Å; S468-I472 WeakPolarHBondContact O-CB 3.48Å; S468-I472 WeakPolarHBondContact O-CG1 3.46Å; S468-I472 PolarHBondContact O-N 3.43Å; L469-I472 PolarHBondContact O-N 3.17Å; I472-I475 PolarHBondContact O-N 3.39Å; I472-M476 VanDerWaalsContact O-CB 3.27Å; I472-M476 WeakPolarHBondContact O-CB 3.42Å; I472-M476 PolarHBondContact O-N 3.33Å; I472-I557 HydrophobicContact CG1-CD1 4.37Å
473	S	91.5	Very high	89.4	Confident	0 Å²	0	20.6 Å²	20.6	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-61.9	-45.7	177.7	-176.3	0	0	0	0	112.1	F299 L469 I471 I475 M476 C477 I517	F299-S473 WeakPolarHBondContact CE1-OG 3.3Å; L469-S473 WeakPolarHBondContact O-CB 3.34Å; L469-S473 PolarHBondContact O-N 2.89Å; I471-S473 VanDerWaalsContact C-N 3.3Å; I471-S473 PolarHBondContact O-N 3.27Å; S473-I475 PolarHBondContact O-N 3.34Å; S473-M476 PolarHBondContact O-N 3.39Å; S473-C477 PolarHBondContact O-N 3.4Å; S473-C477 PolarHBondContact O-SG 3.45Å; S473-C477 VanDerWaalsContact O-SG 3.36Å; S473-I517 WeakPolarHBondContact OG-CD1 3.02Å
474	C	92	Very high	89.7	Confident	11 Å²	11	21.4 Å²	21.4	7%	0.074	10%	0.104	C	C	.	.	H	α-helix	trans	-59.3	-50.4	177.5	-170.3	0	0	0	0	111.6	V470 I471 M476 C477 I478 I517	V470-C474 WeakPolarHBondContact O-CB 3.32Å; V470-C474 PolarHBondContact O-N 3.26Å; I471-C474 PolarHBondContact O-N 3.13Å; C474-M476 VanDerWaalsContact C-N 3.32Å; C474-M476 PolarHBondContact O-N 3.06Å; C474-C477 PolarHBondContact O-N 2.8Å; C474-I478 WeakPolarHBondContact O-CG1 3.46Å; C474-I478 PolarHBondContact O-N 2.89Å; C474-I517 HydrophobicContact CB-CG2 3.68Å
475	I	93.8	Very high	90.1	Very high	41 Å²	41	22.2 Å²	22.2	21%	0.21	11%	0.112	C	C	.	.	H	α-helix	trans	-64	-39.2	-179.8	-66.9	169.9	0	0	0	110.7	F106 V109 I471 I472 S473 I478 C479 I557	F106-I475 HydrophobicContact CD1-CG2 3.55Å; F106-I475 HydrophobicContact CE1-CG2 3.7Å; V109-I475 HydrophobicContact CG2-CG2 3.69Å; I471-I475 HydrophobicContact CG2-CD1 3.72Å; I471-I475 HydrophobicContact CG2-CG1 4.5Å; I471-I475 WeakPolarHBondContact O-CG1 3.41Å; I471-I475 PolarHBondContact O-N 3.32Å; I472-I475 PolarHBondContact O-N 3.39Å; S473-I475 PolarHBondContact O-N 3.34Å; I475-I478 PolarHBondContact O-N 3.18Å; I475-C479 WeakPolarHBondContact O-CB 3.33Å; I475-C479 PolarHBondContact O-N 2.85Å; I475-I557 HydrophobicContact CD1-CD1 3.56Å; I475-I557 HydrophobicContact CD1-CG2 4.34Å; I475-I557 HydrophobicContact CG2-CG2 4.49Å
476	M	94.3	Very high	90.9	Very high	1 Å²	1	24.1 Å²	24.1	1%	0.005	12%	0.121	C	C	.	.	H	α-helix	trans	-59.3	-50.1	174.9	175.9	178.4	69.9	0	0	111.7	E85 W100 M113 I472 S473 C474 I478 C479 I480	E85-M476 HydrophobicContact CG-CE 3.95Å; E85-M476 HydrophobicContact CG-SD 4.03Å; W100-M476 HydrophobicContact CH2-CB 3.81Å; W100-M476 HydrophobicContact CH2-CG 3.76Å; W100-M476 HydrophobicContact CZ2-CB 4.43Å; W100-M476 HydrophobicContact CZ2-CG 4.27Å; M113-M476 HydrophobicContact CE-SD 3.76Å; I472-M476 VanDerWaalsContact O-CB 3.27Å; I472-M476 WeakPolarHBondContact O-CB 3.42Å; I472-M476 PolarHBondContact O-N 3.33Å; S473-M476 PolarHBondContact O-N 3.39Å; C474-M476 VanDerWaalsContact C-N 3.32Å; C474-M476 PolarHBondContact O-N 3.06Å; M476-I478 PolarHBondContact O-N 3.08Å; M476-C479 PolarHBondContact O-N 3.2Å; M476-I480 HydrophobicContact CG-CD1 3.82Å; M476-I480 WeakPolarHBondContact O-CG1 3.43Å; M476-I480 PolarHBondContact O-N 3.03Å
477	C	93.1	Very high	91.7	Very high	1 Å²	1	31.7 Å²	31.7	1%	0.007	15%	0.145	C	C	.	.	H	α-helix	trans	-60.3	-46.1	177.8	-68.8	0	0	0	0	112.1	L81 S473 C474 C479 I480 M481 P514	L81-C477 WeakPolarHBondContact CD2-SG 3.43Å; S473-C477 PolarHBondContact O-N 3.4Å; S473-C477 PolarHBondContact O-SG 3.45Å; S473-C477 VanDerWaalsContact O-SG 3.36Å; C474-C477 PolarHBondContact O-N 2.8Å; C477-C479 VanDerWaalsContact C-N 3.35Å; C477-C479 PolarHBondContact O-N 3.34Å; C477-I480 PolarHBondContact O-N 3.38Å; C477-M481 VanDerWaalsContact O-CB 3.3Å; C477-M481 WeakPolarHBondContact O-CB 3.33Å; C477-M481 WeakPolarHBondContact O-CG 3.08Å; C477-M481 PolarHBondContact O-N 3.38Å; C477-P514 HydrophobicContact CB-CG 4.16Å
478	I	93.1	Very high	92.1	Very high	68 Å²	68	32.5 Å²	32.5	35%	0.349	15%	0.151	S	C	.	.	H	α-helix	trans	-61.4	-46	179.1	-67.9	168.4	0	0	0	110.4	C474 I475 M476 Y482 I483	C474-I478 WeakPolarHBondContact O-CG1 3.46Å; C474-I478 PolarHBondContact O-N 2.89Å; I475-I478 PolarHBondContact O-N 3.18Å; M476-I478 PolarHBondContact O-N 3.08Å; I478-Y482 WeakPolarHBondContact O-CB 3.45Å; I478-Y482 PolarHBondContact O-N 3.38Å; I478-I483 PolarHBondContact O-N 3.25Å
479	C	93.8	Very high	92.4	Very high	0 Å²	0	32.7 Å²	32.7	0%	0	15%	0.152	C	C	.	.	I	π-helix	trans	-60.3	-50.4	-179.9	-179.8	0	0	0	0	111.9	W100 S103 F106 I475 M476 C477 I483 Y484	W100-C479 HydrophobicContact CZ3-CB 4.26Å; S103-C479 VanDerWaalsContact CB-SG 3.56Å; F106-C479 HydrophobicContact CD2-CB 4.1Å; F106-C479 WeakPolarHBondContact CD2-SG 3.26Å; F106-C479 HydrophobicContact CE2-CB 4.39Å; F106-C479 HydrophobicContact CG-CB 4.23Å; I475-C479 WeakPolarHBondContact O-CB 3.33Å; I475-C479 PolarHBondContact O-N 2.85Å; M476-C479 PolarHBondContact O-N 3.2Å; C477-C479 VanDerWaalsContact C-N 3.35Å; C477-C479 PolarHBondContact O-N 3.34Å; C479-I483 WeakPolarHBondContact O-CB 3.35Å; C479-I483 PolarHBondContact O-N 3.26Å; C479-Y484 PolarHBondContact O-N 3.41Å
480	I	94.2	Very high	92.7	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	16%	0.157	C	C	.	.	I	π-helix	trans	-70.8	-42.8	-176	-58.8	172	0	0	0	110.9	L84 F88 M476 C477 G485 Y489	L84-I480 HydrophobicContact CD1-CG2 4.49Å; L84-I480 HydrophobicContact CD2-CD1 4.17Å; L84-I480 HydrophobicContact CG-CD1 4.31Å; F88-I480 HydrophobicContact CD1-CD1 4.14Å; F88-I480 HydrophobicContact CD2-CD1 4.49Å; F88-I480 HydrophobicContact CE1-CD1 4.22Å; F88-I480 HydrophobicContact CG-CD1 4.28Å; F88-I480 HydrophobicContact CZ-CD1 4.44Å; M476-I480 HydrophobicContact CG-CD1 3.82Å; M476-I480 WeakPolarHBondContact O-CG1 3.43Å; M476-I480 PolarHBondContact O-N 3.03Å; C477-I480 PolarHBondContact O-N 3.38Å; I480-G485 PolarHBondContact O-N 3.47Å; I480-Y489 HydrophobicContact CG2-CD1 4.02Å; I480-Y489 HydrophobicContact CG2-CD2 3.43Å; I480-Y489 VanDerWaalsContact CG2-CD2 3.43Å; I480-Y489 HydrophobicContact CG2-CE1 4.24Å; I480-Y489 HydrophobicContact CG2-CE2 3.68Å; I480-Y489 HydrophobicContact CG2-CG 3.6Å
481	M	94.4	Very high	92.9	Very high	1 Å²	1	39.3 Å²	39.3	1%	0.005	18%	0.18	C	C	.	.	I	π-helix	trans	-84.1	-33.5	-171.2	-64.5	-64.5	139.9	0	0	114.2	L84 C477 G485 H486 Y489 F490 W509	L84-M481 HydrophobicContact CD1-CE 3.47Å; L84-M481 VanDerWaalsContact CD1-CE 3.47Å; C477-M481 VanDerWaalsContact O-CB 3.3Å; C477-M481 WeakPolarHBondContact O-CB 3.33Å; C477-M481 WeakPolarHBondContact O-CG 3.08Å; C477-M481 PolarHBondContact O-N 3.38Å; M481-G485 CarbonylContact O-C 3.5Å; M481-H486 PolarHBondContact O-N 3.02Å; M481-H486 HydrophobicContact SD-CB 4.14Å; M481-Y489 HydrophobicContact CE-CD1 3.65Å; M481-Y489 HydrophobicContact CE-CE1 3.95Å; M481-Y489 HydrophobicContact CE-CG 4.37Å; M481-F490 HydrophobicContact SD-CE1 4.25Å; M481-W509 HydrophobicContact CE-CB 3.67Å; M481-W509 HydrophobicContact CE-CD2 4.18Å; M481-W509 HydrophobicContact CE-CE3 4.15Å; M481-W509 HydrophobicContact CE-CG 4.05Å; M481-W509 HydrophobicContact CG-CB 4.2Å; M481-W509 WeakPolarHBondContact CG-O 3.28Å; M481-W509 HydrophobicContact SD-CB 3.65Å
482	Y	93.5	Very high	92.9	Very high	126 Å²	126	37.5 Å²	37.5	49%	0.494	17%	0.171	S	C	.	.	I	π-helix	trans	-110.5	-38.9	-173.6	-62.8	-92.7	0	0	0	113.2	I478 R510	I478-Y482 WeakPolarHBondContact O-CB 3.45Å; I478-Y482 PolarHBondContact O-N 3.38Å; Y482-R510 PolarHBondContact OH-O 3.01Å
483	I	93	Very high	92.8	Very high	66 Å²	66	37.7 Å²	37.7	34%	0.338	17%	0.172	S	C	.	.	I	π-helix	trans	-85.5	-53.9	-175.2	-57.8	-179.9	0	0	0	110.9	F106 I478 C479 G485 C581	F106-I483 HydrophobicContact CD2-CD1 4.34Å; F106-I483 HydrophobicContact CE2-CD1 3.2Å; F106-I483 HydrophobicContact CE2-CG1 4.47Å; F106-I483 HydrophobicContact CE2-CG2 4.37Å; F106-I483 HydrophobicContact CZ-CD1 3.34Å; I478-I483 PolarHBondContact O-N 3.25Å; C479-I483 WeakPolarHBondContact O-CB 3.35Å; C479-I483 PolarHBondContact O-N 3.26Å; I483-G485 VanDerWaalsContact C-N 3.3Å; I483-C581 HydrophobicContact CG2-CB 3.9Å
484	Y	93.3	Very high	92.6	Very high	20 Å²	20	41.6 Å²	41.6	8%	0.078	19%	0.19	C	C	.	.	T	Hydrogen-bonded Turn	trans	-70.1	-33.5	171.4	179.8	-109.4	0	0	0	111.9	I102 C479 N488 Y489 D492 A583 W587 Y599	I102-Y484 HydrophobicContact CD1-CD1 3.51Å; I102-Y484 HydrophobicContact CD1-CD2 3.87Å; I102-Y484 HydrophobicContact CD1-CE1 3.76Å; I102-Y484 HydrophobicContact CD1-CE2 4.13Å; I102-Y484 HydrophobicContact CD1-CG 3.53Å; I102-Y484 HydrophobicContact CG1-CD1 3.96Å; I102-Y484 HydrophobicContact CG1-CD2 3.31Å; I102-Y484 HydrophobicContact CG1-CE1 4.17Å; I102-Y484 HydrophobicContact CG1-CE2 3.59Å; I102-Y484 HydrophobicContact CG1-CG 3.49Å; I102-Y484 VanDerWaalsContact CG1-CG 3.49Å; C479-Y484 PolarHBondContact O-N 3.41Å; Y484-N488 HydrophobicContact CD1-CB 4.11Å; Y484-N488 HydrophobicContact CE1-CB 3.59Å; Y484-N488 PolarHBondContact O-ND2 3.15Å; Y484-Y489 HydrophobicContact CE1-CD2 4.46Å; Y484-D492 WeakPolarHBondContact CE1-OD2 3.35Å; Y484-D492 VanDerWaalsContact CZ-OD2 3.27Å; Y484-D492 PolarHBondContact OH-OD2 3.37Å; Y484-A583 HydrophobicContact CD2-CB 4.36Å; Y484-A583 HydrophobicContact CE2-CB 4.05Å; Y484-W587 AromaticContact CE2-NE1 3.75Å; Y484-W587 AromaticContact CZ-NE1 3.6Å; Y484-W587 PolarHBondContact OH-NE1 3.25Å; Y484-W587 VanDerWaalsContact OH-NE1 3.17Å; Y484-Y599 PolarHBondContact OH-OH 3.34Å
485	G	93.3	Very high	92.4	Very high	17 Å²	17	43.4 Å²	43.4	18%	0.175	20%	0.198	C	C	.	.	T	Hydrogen-bonded Turn	trans	95.8	121.7	173.1	0	0	0	0	0	112.7	I480 M481 I483 R487 N488 Y489	I480-G485 PolarHBondContact O-N 3.47Å; M481-G485 CarbonylContact O-C 3.5Å; I483-G485 VanDerWaalsContact C-N 3.3Å; G485-R487 PolarHBondContact O-N 3.14Å; G485-R487 VanDerWaalsContact O-N 3.08Å; G485-N488 WeakPolarHBondContact O-CB 3.1Å; G485-N488 PolarHBondContact O-N 2.88Å; G485-Y489 PolarHBondContact O-N 3.48Å
486	H	93.2	Very high	92	Very high	40 Å²	40	41.5 Å²	41.5	19%	0.185	19%	0.188	C	C	.	.	H	α-helix	trans	-50.5	-36.7	-179.4	63.9	-82.9	0	0	0	114.1	M481 N488 Y489 F490 R510	M481-H486 PolarHBondContact O-N 3.02Å; M481-H486 HydrophobicContact SD-CB 4.14Å; H486-N488 VanDerWaalsContact C-N 3.31Å; H486-N488 PolarHBondContact O-N 2.99Å; H486-Y489 PolarHBondContact O-N 3.3Å; H486-F490 HydrophobicContact CB-CE1 4.25Å; H486-F490 HydrophobicContact CB-CE2 4.11Å; H486-F490 HydrophobicContact CB-CZ 3.87Å; H486-F490 AromaticContact CD2-CE2 3.96Å; H486-F490 WeakPolarHBondContact O-CB 3.18Å; H486-F490 VanDerWaalsContact O-CD1 3.31Å; H486-F490 WeakPolarHBondContact O-CD1 3.16Å; H486-F490 WeakPolarHBondContact O-CD2 3.46Å; H486-F490 WeakPolarHBondContact O-CG 3Å; H486-F490 PolarHBondContact O-N 3.15Å; H486-R510 PolarHBondContact NE2-NH1 3.32Å
487	R	92.4	Very high	91.5	Very high	190 Å²	190	41.5 Å²	41.5	72%	0.717	19%	0.188	S	C	*	.	H	α-helix	trans	-63.9	-36.2	178.3	-66.7	-174.1	177.5	177.9	-2.9	112.7	G485 K491	G485-R487 PolarHBondContact O-N 3.14Å; G485-R487 VanDerWaalsContact O-N 3.08Å; R487-K491 WeakPolarHBondContact O-CG 3.19Å; R487-K491 PolarHBondContact O-N 3.3Å
488	N	91.4	Very high	91	Very high	49 Å²	49	44.3 Å²	44.3	26%	0.262	22%	0.217	S	C	.	.	H	α-helix	trans	-72.5	-48.1	177.9	-64.7	-28.6	0	0	0	109.4	Y484 G485 H486 F490 K491 D492 R598	Y484-N488 HydrophobicContact CD1-CB 4.11Å; Y484-N488 HydrophobicContact CE1-CB 3.59Å; Y484-N488 PolarHBondContact O-ND2 3.15Å; G485-N488 WeakPolarHBondContact O-CB 3.1Å; G485-N488 PolarHBondContact O-N 2.88Å; H486-N488 VanDerWaalsContact C-N 3.31Å; H486-N488 PolarHBondContact O-N 2.99Å; N488-F490 PolarHBondContact O-N 3.25Å; N488-K491 WeakPolarHBondContact O-CB 3.31Å; N488-K491 PolarHBondContact O-N 3.07Å; N488-K491 VanDerWaalsContact O-N 3.12Å; N488-D492 PolarHBondContact O-N 3.44Å; N488-R598 PolarHBondContact OD1-NH1 2.93Å; N488-R598 PolarHBondContact OD1-NH2 3.1Å
489	Y	92.9	Very high	90.7	Very high	4 Å²	4	43.2 Å²	43.2	2%	0.016	21%	0.21	C	C	.	.	H	α-helix	trans	-61.7	-40.3	179.8	-169	-103.9	0	0	0	113.1	L84 S87 F88 I480 M481 Y484 G485 H486 K491 D492 V493 W509	L84-Y489 HydrophobicContact CD1-CD1 4.35Å; L84-Y489 HydrophobicContact CD1-CE1 3.43Å; L84-Y489 VanDerWaalsContact CD1-CE1 3.43Å; L84-Y489 WeakPolarHBondContact CD1-OH 3.43Å; L84-Y489 PolarHBondContact O-OH 2.91Å; L84-Y489 VanDerWaalsContact O-OH 3.1Å; S87-Y489 PolarHBondContact OG-OH 3.43Å; F88-Y489 HydrophobicContact CD2-CE2 4.36Å; I480-Y489 HydrophobicContact CG2-CD1 4.02Å; I480-Y489 HydrophobicContact CG2-CD2 3.43Å; I480-Y489 VanDerWaalsContact CG2-CD2 3.43Å; I480-Y489 HydrophobicContact CG2-CE1 4.24Å; I480-Y489 HydrophobicContact CG2-CE2 3.68Å; I480-Y489 HydrophobicContact CG2-CG 3.6Å; M481-Y489 HydrophobicContact CE-CD1 3.65Å; M481-Y489 HydrophobicContact CE-CE1 3.95Å; M481-Y489 HydrophobicContact CE-CG 4.37Å; Y484-Y489 HydrophobicContact CE1-CD2 4.46Å; G485-Y489 PolarHBondContact O-N 3.48Å; H486-Y489 PolarHBondContact O-N 3.3Å; Y489-K491 VanDerWaalsContact C-N 3.28Å; Y489-K491 PolarHBondContact O-N 3.33Å; Y489-D492 WeakPolarHBondContact O-CB 3.24Å; Y489-D492 PolarHBondContact O-N 3.12Å; Y489-D492 VanDerWaalsContact O-N 3.15Å; Y489-V493 HydrophobicContact CD1-CG2 4.11Å; Y489-V493 HydrophobicContact CE1-CG2 3.71Å; Y489-V493 WeakPolarHBondContact O-CG2 3.28Å; Y489-V493 PolarHBondContact O-N 3.17Å; Y489-W509 HydrophobicContact CD1-CZ3 4.46Å; Y489-W509 HydrophobicContact CE1-CE3 4.45Å; Y489-W509 HydrophobicContact CE1-CH2 4.27Å; Y489-W509 HydrophobicContact CE1-CZ3 4.05Å
490	F	93.3	Very high	90.3	Very high	28 Å²	28	46 Å²	46	12%	0.123	23%	0.228	C	C	.	.	H	α-helix	trans	-63.7	-34.8	176.8	-63.2	-11.7	0	0	0	112.5	M481 H486 N488 E494 P501 K506 W509	M481-F490 HydrophobicContact SD-CE1 4.25Å; H486-F490 HydrophobicContact CB-CE1 4.25Å; H486-F490 HydrophobicContact CB-CE2 4.11Å; H486-F490 HydrophobicContact CB-CZ 3.87Å; H486-F490 AromaticContact CD2-CE2 3.96Å; H486-F490 WeakPolarHBondContact O-CB 3.18Å; H486-F490 VanDerWaalsContact O-CD1 3.31Å; H486-F490 WeakPolarHBondContact O-CD1 3.16Å; H486-F490 WeakPolarHBondContact O-CD2 3.46Å; H486-F490 WeakPolarHBondContact O-CG 3Å; H486-F490 PolarHBondContact O-N 3.15Å; N488-F490 PolarHBondContact O-N 3.25Å; F490-E494 VanDerWaalsContact O-CB 3.28Å; F490-E494 WeakPolarHBondContact O-CB 3.39Å; F490-E494 PolarHBondContact O-N 3.22Å; F490-P501 HydrophobicContact CB-CG 4.44Å; F490-P501 HydrophobicContact CD1-CG 4.32Å; F490-K506 HydrophobicContact CD1-CG 4.4Å; F490-K506 HydrophobicContact CD2-CD 4.03Å; F490-K506 HydrophobicContact CD2-CG 3.99Å; F490-K506 HydrophobicContact CE1-CB 4.45Å; F490-K506 HydrophobicContact CE1-CG 4.07Å; F490-K506 HydrophobicContact CE2-CB 3.85Å; F490-K506 HydrophobicContact CE2-CD 3.91Å; F490-K506 HydrophobicContact CE2-CG 3.59Å; F490-K506 HydrophobicContact CG-CG 4.38Å; F490-K506 HydrophobicContact CZ-CB 3.7Å; F490-K506 HydrophobicContact CZ-CD 4.46Å; F490-K506 HydrophobicContact CZ-CG 3.63Å; F490-W509 HydrophobicContact CD1-CE3 4.48Å; F490-W509 AromaticContact CE1-CE3 3.91Å; F490-W509 HydrophobicContact CE1-CE3 3.91Å; F490-W509 HydrophobicContact CE1-CZ3 4.36Å
491	K	91.4	Very high	90	Very high	121 Å²	121	46 Å²	46	53%	0.526	23%	0.228	S	C	.	.	H	α-helix	trans	-70.5	-35.7	173.7	-72.2	-179.6	177.4	-168	0	112.2	R487 N488 Y489 E494 M495	R487-K491 WeakPolarHBondContact O-CG 3.19Å; R487-K491 PolarHBondContact O-N 3.3Å; N488-K491 WeakPolarHBondContact O-CB 3.31Å; N488-K491 PolarHBondContact O-N 3.07Å; N488-K491 VanDerWaalsContact O-N 3.12Å; Y489-K491 VanDerWaalsContact C-N 3.28Å; Y489-K491 PolarHBondContact O-N 3.33Å; K491-E494 PolarHBondContact O-N 3.33Å; K491-M495 WeakPolarHBondContact O-CB 3.14Å; K491-M495 PolarHBondContact O-N 2.89Å
492	D	91	Very high	89.8	Confident	4 Å²	4	48.2 Å²	48.2	2%	0.021	24%	0.242	C	C	.	.	H	α-helix	trans	-65	-43.3	175.7	-61.9	-25	0	0	0	110.9	F91 Y484 N488 Y489 M495 M496 Y599	F91-D492 HydrophobicContact CD1-CB 4.43Å; F91-D492 HydrophobicContact CD2-CB 4.08Å; F91-D492 WeakPolarHBondContact CD2-O 3.3Å; F91-D492 HydrophobicContact CE1-CB 4.05Å; F91-D492 HydrophobicContact CE2-CB 3.67Å; F91-D492 HydrophobicContact CG-CB 4.44Å; F91-D492 HydrophobicContact CZ-CB 3.65Å; Y484-D492 WeakPolarHBondContact CE1-OD2 3.35Å; Y484-D492 VanDerWaalsContact CZ-OD2 3.27Å; Y484-D492 PolarHBondContact OH-OD2 3.37Å; N488-D492 PolarHBondContact O-N 3.44Å; Y489-D492 WeakPolarHBondContact O-CB 3.24Å; Y489-D492 PolarHBondContact O-N 3.12Å; Y489-D492 VanDerWaalsContact O-N 3.15Å; D492-M495 PolarHBondContact O-N 2.96Å; D492-M496 PolarHBondContact O-N 2.89Å; D492-M496 VanDerWaalsContact O-N 3.12Å; D492-Y599 WeakPolarHBondContact OD1-CE2 3.25Å; D492-Y599 PolarHBondContact OD1-OH 2.86Å; D492-Y599 PolarHBondContact OD2-OH 3.46Å
493	V	89.1	Confident	89.7	Confident	4 Å²	4	48.6 Å²	48.6	2%	0.024	25%	0.252	C	S	.	.	H	α-helix	trans	-66.9	-39	174.5	179.6	0	0	0	0	111.2	F83 Y489 M496 L497 P501	F83-V493 HydrophobicContact CZ-CG1 4.38Å; Y489-V493 HydrophobicContact CD1-CG2 4.11Å; Y489-V493 HydrophobicContact CE1-CG2 3.71Å; Y489-V493 WeakPolarHBondContact O-CG2 3.28Å; Y489-V493 PolarHBondContact O-N 3.17Å; V493-M496 PolarHBondContact O-N 2.95Å; V493-L497 HydrophobicContact CG1-CD1 3.51Å; V493-L497 HydrophobicContact CG1-CG 4.01Å; V493-L497 WeakPolarHBondContact O-CB 3.28Å; V493-L497 WeakPolarHBondContact O-CG 3.39Å; V493-L497 PolarHBondContact O-N 3.33Å; V493-P501 HydrophobicContact CB-CG 3.84Å; V493-P501 HydrophobicContact CG1-CG 3.69Å
494	E	89	Confident	89.7	Confident	82 Å²	82	49.4 Å²	49.4	38%	0.383	25%	0.253	S	S	.	.	H	α-helix	trans	-64	-37.8	174.6	-177.2	172.1	-169.3	0	0	112.5	F490 K491 M496 G498 F499 P500	F490-E494 VanDerWaalsContact O-CB 3.28Å; F490-E494 WeakPolarHBondContact O-CB 3.39Å; F490-E494 PolarHBondContact O-N 3.22Å; K491-E494 PolarHBondContact O-N 3.33Å; E494-M496 VanDerWaalsContact C-N 3.32Å; E494-M496 PolarHBondContact O-N 3.48Å; E494-G498 CarbonylContact O-C 3.57Å; E494-G498 WeakPolarHBondContact O-CA 3.08Å; E494-G498 PolarHBondContact O-N 3.21Å; E494-F499 WeakPolarHBondContact CA-O 3.35Å; E494-P500 HydrophobicContact CG-CB 4.37Å
495	M	87.1	Confident	89.6	Confident	49 Å²	49	48.8 Å²	48.8	24%	0.241	25%	0.251	C	S	.	.	H	α-helix	trans	-63.6	-38.9	173.9	176.7	-177.3	-73.1	0	0	111.8	F91 F318 H319 K491 D492 P589 Y599	F91-M495 HydrophobicContact CE2-SD 4.21Å; F318-M495 HydrophobicContact CZ-CG 4.35Å; H319-M495 PolarHBondContact CE1-O 2.69Å; K491-M495 WeakPolarHBondContact O-CB 3.14Å; K491-M495 PolarHBondContact O-N 2.89Å; D492-M495 PolarHBondContact O-N 2.96Å; M495-P589 HydrophobicContact SD-CG 4.39Å; M495-Y599 HydrophobicContact CE-CD2 3.97Å; M495-Y599 HydrophobicContact CE-CE2 4.31Å; M495-Y599 HydrophobicContact SD-CD2 4.02Å; M495-Y599 HydrophobicContact SD-CE2 4.33Å
496	M	85.7	Confident	89.6	Confident	1 Å²	1	50.5 Å²	50.5	1%	0.005	25%	0.254	C	S	.	.	H	α-helix	trans	-75.9	-44.4	179.5	-173.8	-174.3	71	0	0	112.4	Q90 F91 F318 D492 V493 E494	Q90-M496 HydrophobicContact CB-SD 3.77Å; Q90-M496 HydrophobicContact CG-SD 3.58Å; Q90-M496 VanDerWaalsContact CG-SD 3.58Å; F91-M496 HydrophobicContact CB-SD 4.14Å; F91-M496 HydrophobicContact CD2-CB 4.38Å; F318-M496 WeakPolarHBondContact O-CG 3.4Å; D492-M496 PolarHBondContact O-N 2.89Å; D492-M496 VanDerWaalsContact O-N 3.12Å; V493-M496 PolarHBondContact O-N 2.95Å; E494-M496 VanDerWaalsContact C-N 3.32Å; E494-M496 PolarHBondContact O-N 3.48Å
497	L	83.1	Confident	89.6	Confident	1 Å²	1	51.3 Å²	51.3	1%	0.005	26%	0.262	C	S	.	.	H	α-helix	trans	-95.9	-3.9	-173.7	-60.1	-177.2	0	0	0	113.9	F83 C322 V493 F499	F83-L497 HydrophobicContact CE2-CD1 4.24Å; F83-L497 HydrophobicContact CZ-CD1 3.77Å; C322-L497 WeakPolarHBondContact CA-O 3.39Å; C322-L497 WeakPolarHBondContact CB-O 3.19Å; C322-L497 WeakPolarHBondContact O-CD2 3.35Å; C322-L497 PolarHBondContact SG-O 3.26Å; V493-L497 HydrophobicContact CG1-CD1 3.51Å; V493-L497 HydrophobicContact CG1-CG 4.01Å; V493-L497 WeakPolarHBondContact O-CB 3.28Å; V493-L497 WeakPolarHBondContact O-CG 3.39Å; V493-L497 PolarHBondContact O-N 3.33Å; L497-F499 HydrophobicContact CB-CD1 4.39Å; L497-F499 HydrophobicContact CB-CE1 4.23Å; L497-F499 HydrophobicContact CB-CZ 4.36Å; L497-F499 HydrophobicContact CD1-CZ 4.4Å; L497-F499 WeakPolarHBondContact O-CD1 3.11Å; L497-F499 WeakPolarHBondContact O-CE1 3.49Å; L497-F499 PolarHBondContact O-N 2.95Å
498	G	83.5	Confident	89.7	Confident	59 Å²	59	42.3 Å²	42.3	61%	0.608	23%	0.227	S	C	*	.	S	Bend	trans	65.4	-3.5	-176.1	0	0	0	0	0	115.9	E494	E494-G498 CarbonylContact O-C 3.57Å; E494-G498 WeakPolarHBondContact O-CA 3.08Å; E494-G498 PolarHBondContact O-N 3.21Å
499	F	85.2	Confident	89.9	Confident	46 Å²	46	40 Å²	40	20%	0.202	22%	0.215	C	C	.	.	S	Bend	trans	-140.8	150.2	173.7	62.9	-96.2	0	0	0	110.6	C322 F323 E494 L497	C322-F499 HydrophobicContact CB-CD1 4.39Å; C322-F499 HydrophobicContact CB-CE1 4.3Å; C322-F499 WeakPolarHBondContact O-CE1 3.28Å; C322-F499 WeakPolarHBondContact O-CZ 3.33Å; F323-F499 HydrophobicContact CD2-CD1 4.4Å; F323-F499 AromaticContact CD2-CE1 3.76Å; F323-F499 HydrophobicContact CD2-CE1 3.76Å; F323-F499 HydrophobicContact CD2-CZ 4.31Å; F323-F499 HydrophobicContact CE2-CE1 4.28Å; F323-F499 HydrophobicContact CG-CE1 4.4Å; E494-F499 WeakPolarHBondContact CA-O 3.35Å; L497-F499 HydrophobicContact CB-CD1 4.39Å; L497-F499 HydrophobicContact CB-CE1 4.23Å; L497-F499 HydrophobicContact CB-CZ 4.36Å; L497-F499 HydrophobicContact CD1-CZ 4.4Å; L497-F499 WeakPolarHBondContact O-CD1 3.11Å; L497-F499 WeakPolarHBondContact O-CE1 3.49Å; L497-F499 PolarHBondContact O-N 2.95Å
500	P	86.6	Confident	89.9	Confident	58 Å²	58	44.1 Å²	44.1	38%	0.377	23%	0.231	S	C	.	.	P	Polyproline II helix	trans	-69.7	147.8	-178.6	28.6	-36	0	0	0	111.2	E494	E494-P500 HydrophobicContact CG-CB 4.37Å
501	P	87.6	Confident	89.9	Confident	1 Å²	1	47.4 Å²	47.4	1%	0.006	25%	0.245	C	C	.	.	P	Polyproline II helix	trans	-52.1	139.3	177.5	-25.4	31	0	0	0	112.1	F490 V493 K506 W509	F490-P501 HydrophobicContact CB-CG 4.44Å; F490-P501 HydrophobicContact CD1-CG 4.32Å; V493-P501 HydrophobicContact CB-CG 3.84Å; V493-P501 HydrophobicContact CG1-CG 3.69Å; P501-K506 HydrophobicContact CB-CG 4.11Å; P501-K506 WeakPolarHBondContact O-CD 3.33Å; P501-K506 WeakPolarHBondContact O-CE 3.38Å; P501-K506 PolarHBondContact O-NZ 3.2Å; P501-W509 HydrophobicContact CB-CZ3 4.11Å; P501-W509 HydrophobicContact CG-CZ3 4.21Å
502	P	89.8	Confident	90	Very high	46 Å²	46	44 Å²	44	30%	0.299	23%	0.232	S	C	.	.	P	Polyproline II helix	trans	-57.5	152.4	176.4	-22.6	31.4	0	0	0	112	F504 F505 K506	P502-F504 PolarHBondContact O-N 3.06Å; P502-F505 HydrophobicContact CB-CD2 4.1Å; P502-F505 HydrophobicContact CG-CD2 4.06Å; P502-F505 HydrophobicContact CG-CE2 4.43Å; P502-F505 PolarHBondContact O-N 2.97Å; P502-F505 VanDerWaalsContact O-N 3.13Å; P502-K506 PolarHBondContact O-N 3.24Å
503	L	91.3	Very high	90	Very high	134 Å²	134	43.9 Å²	43.9	70%	0.702	23%	0.231	S	C	*	.	H	α-helix	trans	-54.9	-39.3	-176.1	-178.1	62.9	0	0	0	112.5	F505 K506 V507	L503-F505 PolarHBondContact O-N 3.32Å; L503-K506 WeakPolarHBondContact O-CB 3.28Å; L503-K506 PolarHBondContact O-N 3.26Å; L503-V507 HydrophobicContact CD1-CG2 4.12Å; L503-V507 HydrophobicContact CG-CG2 4.29Å; L503-V507 WeakPolarHBondContact O-CG2 3.5Å; L503-V507 PolarHBondContact O-N 2.57Å
504	F	92.6	Very high	90.1	Very high	83 Å²	83	44.1 Å²	44.1	36%	0.364	23%	0.233	S	C	.	.	H	α-helix	trans	-52.7	-51.5	177.3	176.6	-101.9	0	0	0	112.7	V75 F76 P80 P502 K506 V507 C508	V75-F504 HydrophobicContact CG1-CE2 4.28Å; V75-F504 HydrophobicContact CG1-CZ 3.76Å; V75-F504 VanDerWaalsContact O-CZ 3.32Å; V75-F504 WeakPolarHBondContact O-CZ 3.39Å; F76-F504 HydrophobicContact CD1-CE2 4.22Å; F76-F504 HydrophobicContact CD1-CZ 4.45Å; F76-F504 HydrophobicContact CE1-CE2 4.03Å; P80-F504 HydrophobicContact CG-CE1 4.23Å; P502-F504 PolarHBondContact O-N 3.06Å; F504-K506 PolarHBondContact O-N 3.49Å; F504-V507 PolarHBondContact O-N 3.45Å; F504-C508 VanDerWaalsContact CZ-SG 3.52Å; F504-C508 WeakPolarHBondContact O-CB 3.45Å; F504-C508 PolarHBondContact O-N 3.24Å; F504-C508 PolarHBondContact O-SG 3.17Å
505	F	92	Very high	90.2	Very high	7 Å²	7	45 Å²	45	3%	0.031	24%	0.244	C	C	.	.	H	α-helix	trans	-67.6	-37.7	179.6	-68.3	-83.7	0	0	0	112.1	I79 P80 F83 H326 P502 L503 V507 C508 W509	I79-F505 HydrophobicContact CG2-CE1 4.03Å; I79-F505 HydrophobicContact CG2-CZ 4.19Å; P80-F505 HydrophobicContact CB-CD1 4.38Å; F83-F505 HydrophobicContact CB-CD1 4.39Å; F83-F505 HydrophobicContact CB-CE1 4.09Å; F83-F505 AromaticContact CD1-CD1 3.55Å; F83-F505 HydrophobicContact CD1-CD1 3.55Å; F83-F505 AromaticContact CD1-CE1 3.79Å; F83-F505 HydrophobicContact CD1-CE1 3.79Å; F83-F505 AromaticContact CD1-CG 3.95Å; F83-F505 HydrophobicContact CD1-CG 3.95Å; F83-F505 HydrophobicContact CD1-CZ 4.43Å; F83-F505 HydrophobicContact CE1-CD1 4.33Å; F83-F505 HydrophobicContact CE1-CG 4.28Å; F83-F505 HydrophobicContact CG-CD1 4.4Å; F83-F505 HydrophobicContact CG-CE1 4.28Å; H326-F505 AromaticContact CE1-CE2 3.32Å; H326-F505 WeakPolarHBondContact CE1-CE2 3.38Å; H326-F505 AromaticContact CE1-CZ 3.65Å; H326-F505 AromaticContact ND1-CE2 3.67Å; H326-F505 AromaticContact ND1-CZ 3.8Å; P502-F505 HydrophobicContact CB-CD2 4.1Å; P502-F505 HydrophobicContact CG-CD2 4.06Å; P502-F505 HydrophobicContact CG-CE2 4.43Å; P502-F505 PolarHBondContact O-N 2.97Å; P502-F505 VanDerWaalsContact O-N 3.13Å; L503-F505 PolarHBondContact O-N 3.32Å; F505-V507 VanDerWaalsContact C-N 3.31Å; F505-V507 PolarHBondContact O-N 2.03Å; F505-C508 PolarHBondContact O-N 3.4Å; F505-W509 HydrophobicContact CB-CD2 4.32Å; F505-W509 HydrophobicContact CB-CE3 4.28Å; F505-W509 HydrophobicContact CB-CH2 4.4Å; F505-W509 HydrophobicContact CB-CZ2 4.39Å; F505-W509 HydrophobicContact CB-CZ3 4.32Å; F505-W509 HydrophobicContact CD1-CZ2 4.38Å; F505-W509 WeakPolarHBondContact O-CB 3.46Å; F505-W509 VanDerWaalsContact O-CG 3.24Å; F505-W509 PolarHBondContact O-N 3.45Å
506	K	92.6	Very high	90.3	Very high	54 Å²	54	44.2 Å²	44.2	24%	0.235	24%	0.24	C	C	.	.	H	α-helix	trans	-59.5	-43.2	175.9	-67.1	176.6	167.1	149.6	0	111.6	F490 P501 P502 L503 F504 R510	F490-K506 HydrophobicContact CD1-CG 4.4Å; F490-K506 HydrophobicContact CD2-CD 4.03Å; F490-K506 HydrophobicContact CD2-CG 3.99Å; F490-K506 HydrophobicContact CE1-CB 4.45Å; F490-K506 HydrophobicContact CE1-CG 4.07Å; F490-K506 HydrophobicContact CE2-CB 3.85Å; F490-K506 HydrophobicContact CE2-CD 3.91Å; F490-K506 HydrophobicContact CE2-CG 3.59Å; F490-K506 HydrophobicContact CG-CG 4.38Å; F490-K506 HydrophobicContact CZ-CB 3.7Å; F490-K506 HydrophobicContact CZ-CD 4.46Å; F490-K506 HydrophobicContact CZ-CG 3.63Å; P501-K506 HydrophobicContact CB-CG 4.11Å; P501-K506 WeakPolarHBondContact O-CD 3.33Å; P501-K506 WeakPolarHBondContact O-CE 3.38Å; P501-K506 PolarHBondContact O-NZ 3.2Å; P502-K506 PolarHBondContact O-N 3.24Å; L503-K506 WeakPolarHBondContact O-CB 3.28Å; L503-K506 PolarHBondContact O-N 3.26Å; F504-K506 PolarHBondContact O-N 3.49Å; K506-R510 WeakPolarHBondContact O-CB 3.13Å; K506-R510 PolarHBondContact O-N 2.98Å
507	V	94.9	Very high	90.5	Very high	57 Å²	57	44.1 Å²	44.1	35%	0.345	24%	0.24	S	C	.	.	H	α-helix	trans	-71.2	-42.9	177.5	176	0	0	0	0	110.8	L503 F504 F505 R510 F511 I512	L503-V507 HydrophobicContact CD1-CG2 4.12Å; L503-V507 HydrophobicContact CG-CG2 4.29Å; L503-V507 WeakPolarHBondContact O-CG2 3.5Å; L503-V507 PolarHBondContact O-N 2.57Å; F504-V507 PolarHBondContact O-N 3.45Å; F505-V507 VanDerWaalsContact C-N 3.31Å; F505-V507 PolarHBondContact O-N 2.03Å; V507-R510 PolarHBondContact O-N 3.26Å; V507-F511 PolarHBondContact O-N 3.33Å; V507-I512 HydrophobicContact CG1-CD1 3.85Å; V507-I512 HydrophobicContact CG1-CG1 4.14Å; V507-I512 PolarHBondContact O-N 3.38Å
508	C	94.4	Very high	90.7	Very high	0 Å²	0	46.1 Å²	46.1	0%	0	25%	0.254	C	S	.	.	I	π-helix	trans	-61.4	-53.7	180	-69.9	0	0	0	0	111.9	P80 F504 F505 R510 I512 S513	P80-C508 HydrophobicContact CB-CB 3.74Å; P80-C508 HydrophobicContact CG-CB 3.63Å; F504-C508 VanDerWaalsContact CZ-SG 3.52Å; F504-C508 WeakPolarHBondContact O-CB 3.45Å; F504-C508 PolarHBondContact O-N 3.24Å; F504-C508 PolarHBondContact O-SG 3.17Å; F505-C508 PolarHBondContact O-N 3.4Å; C508-R510 VanDerWaalsContact C-N 3.31Å; C508-R510 PolarHBondContact O-N 2.94Å; C508-I512 PolarHBondContact O-N 3.14Å; C508-S513 WeakPolarHBondContact O-CB 2.88Å; C508-S513 PolarHBondContact O-N 2.65Å; C508-S513 PolarHBondContact O-OG 3.18Å
509	W	94.2	Very high	90.8	Very high	1 Å²	1	48.6 Å²	48.6	0%	0.004	25%	0.248	C	C	.	.	I	π-helix	trans	-61.9	-39.8	-179.7	-65.9	-28.8	0	0	0	112.9	P80 F83 L84 M481 Y489 F490 P501 F505 P514	P80-W509 VanDerWaalsContact C-NE1 3.32Å; P80-W509 PolarHBondContact O-NE1 3.42Å; F83-W509 HydrophobicContact CB-CZ2 4.22Å; F83-W509 AromaticContact CD1-CH2 3.42Å; F83-W509 HydrophobicContact CD1-CH2 3.42Å; F83-W509 VanDerWaalsContact CD1-CH2 3.42Å; F83-W509 AromaticContact CD1-CZ2 3.19Å; F83-W509 HydrophobicContact CD1-CZ2 3.19Å; F83-W509 AromaticContact CE1-CH2 3.37Å; F83-W509 HydrophobicContact CE1-CH2 3.37Å; F83-W509 AromaticContact CE1-CZ2 3.71Å; F83-W509 HydrophobicContact CE1-CZ2 3.71Å; F83-W509 HydrophobicContact CE1-CZ3 4.42Å; F83-W509 HydrophobicContact CG-CH2 4.39Å; F83-W509 AromaticContact CG-CZ2 3.94Å; F83-W509 HydrophobicContact CG-CZ2 3.94Å; F83-W509 HydrophobicContact CZ-CH2 4.32Å; L84-W509 HydrophobicContact CB-CZ2 4.08Å; L84-W509 HydrophobicContact CD1-CD2 3.92Å; L84-W509 HydrophobicContact CD1-CE3 4.42Å; L84-W509 HydrophobicContact CD1-CG 4.17Å; L84-W509 HydrophobicContact CD1-CZ2 4.05Å; M481-W509 HydrophobicContact CE-CB 3.67Å; M481-W509 HydrophobicContact CE-CD2 4.18Å; M481-W509 HydrophobicContact CE-CE3 4.15Å; M481-W509 HydrophobicContact CE-CG 4.05Å; M481-W509 HydrophobicContact CG-CB 4.2Å; M481-W509 WeakPolarHBondContact CG-O 3.28Å; M481-W509 HydrophobicContact SD-CB 3.65Å; Y489-W509 HydrophobicContact CD1-CZ3 4.46Å; Y489-W509 HydrophobicContact CE1-CE3 4.45Å; Y489-W509 HydrophobicContact CE1-CH2 4.27Å; Y489-W509 HydrophobicContact CE1-CZ3 4.05Å; F490-W509 HydrophobicContact CD1-CE3 4.48Å; F490-W509 AromaticContact CE1-CE3 3.91Å; F490-W509 HydrophobicContact CE1-CE3 3.91Å; F490-W509 HydrophobicContact CE1-CZ3 4.36Å; P501-W509 HydrophobicContact CB-CZ3 4.11Å; P501-W509 HydrophobicContact CG-CZ3 4.21Å; F505-W509 HydrophobicContact CB-CD2 4.32Å; F505-W509 HydrophobicContact CB-CE3 4.28Å; F505-W509 HydrophobicContact CB-CH2 4.4Å; F505-W509 HydrophobicContact CB-CZ2 4.39Å; F505-W509 HydrophobicContact CB-CZ3 4.32Å; F505-W509 HydrophobicContact CD1-CZ2 4.38Å; F505-W509 WeakPolarHBondContact O-CB 3.46Å; F505-W509 VanDerWaalsContact O-CG 3.24Å; F505-W509 PolarHBondContact O-N 3.45Å; W509-P514 WeakPolarHBondContact O-CD 3.14Å; W509-P514 WeakPolarHBondContact O-CG 3.13Å
510	R	93.6	Very high	90.8	Very high	90 Å²	90	46.5 Å²	46.5	34%	0.34	24%	0.239	S	C	.	.	I	π-helix	trans	-77.1	-39	-175.6	-174.6	172.8	173.6	-175.9	-4.6	113.1	Y482 H486 K506 V507 C508	Y482-R510 PolarHBondContact OH-O 3.01Å; H486-R510 PolarHBondContact NE2-NH1 3.32Å; K506-R510 WeakPolarHBondContact O-CB 3.13Å; K506-R510 PolarHBondContact O-N 2.98Å; V507-R510 PolarHBondContact O-N 3.26Å; C508-R510 VanDerWaalsContact C-N 3.31Å; C508-R510 PolarHBondContact O-N 2.94Å
511	F	93.5	Very high	90.7	Very high	97 Å²	97	45.7 Å²	45.7	43%	0.425	23%	0.231	S	C	.	.	I	π-helix	trans	-126.5	-54.6	-169.1	-59.8	-68	0	0	0	112.7	V507 V515	V507-F511 PolarHBondContact O-N 3.33Å; F511-V515 WeakPolarHBondContact O-CB 3.31Å; F511-V515 WeakPolarHBondContact O-CG2 3.4Å; F511-V515 PolarHBondContact O-N 2.84Å
512	I	93.1	Very high	90.7	Very high	51 Å²	51	50.6 Å²	50.6	26%	0.262	26%	0.256	S	S	.	.	I	π-helix	trans	-70.5	-54	-166.8	-55.3	174.6	0	0	0	111.4	F76 V507 C508 V515 I516	F76-I512 HydrophobicContact CB-CG2 3.87Å; F76-I512 HydrophobicContact CD1-CD1 3.86Å; F76-I512 HydrophobicContact CD1-CG2 4.05Å; F76-I512 HydrophobicContact CE1-CD1 4.15Å; F76-I512 HydrophobicContact CG-CG2 4.26Å; V507-I512 HydrophobicContact CG1-CD1 3.85Å; V507-I512 HydrophobicContact CG1-CG1 4.14Å; V507-I512 PolarHBondContact O-N 3.38Å; C508-I512 PolarHBondContact O-N 3.14Å; I512-V515 PolarHBondContact O-N 3.01Å; I512-I516 HydrophobicContact CG2-CD1 3.52Å; I512-I516 HydrophobicContact CG2-CG1 4.25Å; I512-I516 WeakPolarHBondContact O-CG1 2.79Å; I512-I516 PolarHBondContact O-N 3.03Å
513	S	91.3	Very high	90.2	Very high	0 Å²	0	49.5 Å²	49.5	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-63.2	-45.9	-176.3	-45.1	0	0	0	0	112.3	F76 C508 V515 I516 I517	F76-S513 PolarHBondContact O-OG 3.14Å; C508-S513 WeakPolarHBondContact O-CB 2.88Å; C508-S513 PolarHBondContact O-N 2.65Å; C508-S513 PolarHBondContact O-OG 3.18Å; S513-V515 VanDerWaalsContact C-N 3.33Å; S513-V515 PolarHBondContact O-N 2.98Å; S513-I516 PolarHBondContact O-N 2.94Å; S513-I517 WeakPolarHBondContact O-CB 3.28Å; S513-I517 WeakPolarHBondContact O-CD1 3.25Å; S513-I517 WeakPolarHBondContact O-CG1 3.45Å; S513-I517 PolarHBondContact O-N 2.86Å
514	P	91.1	Very high	89.6	Confident	9 Å²	9	44.5 Å²	44.5	6%	0.058	22%	0.222	C	C	.	.	H	α-helix	trans	-59.3	-40.1	175.5	-23.3	32.4	0	0	0	113.7	C477 W509 S518	C477-P514 HydrophobicContact CB-CG 4.16Å; W509-P514 WeakPolarHBondContact O-CD 3.14Å; W509-P514 WeakPolarHBondContact O-CG 3.13Å; P514-S518 VanDerWaalsContact O-CB 3.28Å; P514-S518 WeakPolarHBondContact O-CB 3.31Å; P514-S518 PolarHBondContact O-N 3.23Å; P514-S518 PolarHBondContact O-OG 2.79Å
515	V	91.7	Very high	89.1	Confident	101 Å²	101	44.9 Å²	44.9	61%	0.612	23%	0.231	S	C	*	.	H	α-helix	trans	-66.9	-47.3	178.7	168.9	0	0	0	0	110.7	F511 I512 S513 S518 F519	F511-V515 WeakPolarHBondContact O-CB 3.31Å; F511-V515 WeakPolarHBondContact O-CG2 3.4Å; F511-V515 PolarHBondContact O-N 2.84Å; I512-V515 PolarHBondContact O-N 3.01Å; S513-V515 VanDerWaalsContact C-N 3.33Å; S513-V515 PolarHBondContact O-N 2.98Å; V515-S518 PolarHBondContact O-N 3.11Å; V515-F519 WeakPolarHBondContact O-CB 3.26Å; V515-F519 PolarHBondContact O-N 3.26Å
516	I	89.4	Confident	88.8	Confident	32 Å²	32	50.6 Å²	50.6	16%	0.164	26%	0.26	C	S	.	.	H	α-helix	trans	-64.1	-45.3	179.1	-67.5	174.5	0	0	0	110.8	M73 F76 C77 I512 S513 S518 F519 I520	M73-I516 HydrophobicContact CE-CG2 4Å; M73-I516 HydrophobicContact SD-CG2 3.66Å; F76-I516 HydrophobicContact CB-CD1 4.08Å; C77-I516 WeakPolarHBondContact SG-CB 3.25Å; C77-I516 WeakPolarHBondContact SG-CG2 3.46Å; I512-I516 HydrophobicContact CG2-CD1 3.52Å; I512-I516 HydrophobicContact CG2-CG1 4.25Å; I512-I516 WeakPolarHBondContact O-CG1 2.79Å; I512-I516 PolarHBondContact O-N 3.03Å; S513-I516 PolarHBondContact O-N 2.94Å; I516-S518 VanDerWaalsContact C-N 3.33Å; I516-S518 PolarHBondContact O-N 3.34Å; I516-F519 WeakPolarHBondContact O-CB 3.35Å; I516-F519 PolarHBondContact O-N 3.36Å; I516-I520 HydrophobicContact CG2-CD1 3.59Å; I516-I520 HydrophobicContact CG2-CG1 4.28Å; I516-I520 WeakPolarHBondContact O-CD1 3.24Å; I516-I520 VanDerWaalsContact O-CG1 3.23Å; I516-I520 WeakPolarHBondContact O-CG1 3.14Å; I516-I520 PolarHBondContact O-N 3.48Å
517	I	88.7	Confident	88.1	Confident	0 Å²	0	51.6 Å²	51.6	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-61.5	-42.7	177.8	-65.3	162.3	0	0	0	111	L81 F299 V470 S473 C474 S513 F519 I520 L521	L81-I517 HydrophobicContact CD1-CD1 3.61Å; L81-I517 HydrophobicContact CD1-CG1 4.34Å; L81-I517 HydrophobicContact CD2-CD1 4.13Å; L81-I517 HydrophobicContact CG-CD1 4.48Å; F299-I517 HydrophobicContact CE2-CG1 4.39Å; F299-I517 HydrophobicContact CZ-CD1 4.1Å; F299-I517 HydrophobicContact CZ-CG1 3.69Å; V470-I517 HydrophobicContact CG1-CG2 3.85Å; V470-I517 WeakPolarHBondContact O-CG2 3.26Å; S473-I517 WeakPolarHBondContact OG-CD1 3.02Å; C474-I517 HydrophobicContact CB-CG2 3.68Å; S513-I517 WeakPolarHBondContact O-CB 3.28Å; S513-I517 WeakPolarHBondContact O-CD1 3.25Å; S513-I517 WeakPolarHBondContact O-CG1 3.45Å; S513-I517 PolarHBondContact O-N 2.86Å; I517-F519 VanDerWaalsContact C-N 3.34Å; I517-I520 PolarHBondContact O-N 2.65Å; I517-L521 WeakPolarHBondContact O-CB 3.44Å; I517-L521 PolarHBondContact O-N 2.89Å
518	S	88	Confident	87.6	Confident	42 Å²	42	52.5 Å²	52.5	29%	0.294	26%	0.264	S	S	.	.	H	α-helix	trans	-64.1	-40.8	177.2	-59.2	0	0	0	0	111.6	P514 V515 I516 L521 I522	P514-S518 VanDerWaalsContact O-CB 3.28Å; P514-S518 WeakPolarHBondContact O-CB 3.31Å; P514-S518 PolarHBondContact O-N 3.23Å; P514-S518 PolarHBondContact O-OG 2.79Å; V515-S518 PolarHBondContact O-N 3.11Å; I516-S518 VanDerWaalsContact C-N 3.33Å; I516-S518 PolarHBondContact O-N 3.34Å; S518-L521 PolarHBondContact O-N 2.86Å; S518-I522 WeakPolarHBondContact O-CG1 3.31Å; S518-I522 PolarHBondContact O-N 2.95Å; S518-I522 VanDerWaalsContact O-N 3.1Å
519	F	86.3	Confident	87	Confident	111 Å²	111	60.2 Å²	60.2	49%	0.487	30%	0.297	S	S	.	.	H	α-helix	trans	-62.1	-46.4	174.4	175.9	-98.6	0	0	0	111.7	V515 I516 I517 L521 I522 F523	V515-F519 WeakPolarHBondContact O-CB 3.26Å; V515-F519 PolarHBondContact O-N 3.26Å; I516-F519 WeakPolarHBondContact O-CB 3.35Å; I516-F519 PolarHBondContact O-N 3.36Å; I517-F519 VanDerWaalsContact C-N 3.34Å; F519-L521 VanDerWaalsContact C-N 3.32Å; F519-L521 PolarHBondContact O-N 3.44Å; F519-I522 PolarHBondContact O-N 3.29Å; F519-F523 VanDerWaalsContact O-CB 3.24Å; F519-F523 WeakPolarHBondContact O-CB 3.2Å; F519-F523 PolarHBondContact O-N 3.47Å
520	I	84.4	Confident	86.6	Confident	2 Å²	2	63.6 Å²	63.6	1%	0.01	32%	0.319	C	S	.	.	H	α-helix	trans	-58.6	-45.9	175.8	-66.7	155.9	0	0	0	110.1	A295 F299 V470 I516 I517 I522 F523 T524	A295-I520 HydrophobicContact CB-CD1 3.28Å; A295-I520 HydrophobicContact CB-CG1 3.81Å; F299-I520 HydrophobicContact CE2-CD1 4.23Å; V470-I520 HydrophobicContact CG1-CB 4.47Å; V470-I520 HydrophobicContact CG1-CG2 4.16Å; V470-I520 HydrophobicContact CG2-CG2 4.31Å; I516-I520 HydrophobicContact CG2-CD1 3.59Å; I516-I520 HydrophobicContact CG2-CG1 4.28Å; I516-I520 WeakPolarHBondContact O-CD1 3.24Å; I516-I520 VanDerWaalsContact O-CG1 3.23Å; I516-I520 WeakPolarHBondContact O-CG1 3.14Å; I516-I520 PolarHBondContact O-N 3.48Å; I517-I520 PolarHBondContact O-N 2.65Å; I520-I522 PolarHBondContact O-N 3.09Å; I520-F523 PolarHBondContact O-N 3.28Å; I520-F523 VanDerWaalsContact O-N 3.15Å; I520-T524 WeakPolarHBondContact O-CB 3.21Å; I520-T524 PolarHBondContact O-N 3.42Å; I520-T524 PolarHBondContact O-OG1 3.03Å
521	L	85.3	Confident	86.3	Confident	42 Å²	42	60.1 Å²	60.1	22%	0.22	31%	0.307	C	S	.	.	H	α-helix	trans	-57.4	-50.2	179.9	-178.7	60.3	0	0	0	112.1	V470 I471 I517 S518 F519 F523 T524 V525	V470-L521 HydrophobicContact CB-CD1 4.39Å; V470-L521 HydrophobicContact CG1-CB 3.76Å; V470-L521 HydrophobicContact CG1-CD1 4.16Å; I471-L521 HydrophobicContact CD1-CD1 4.16Å; I471-L521 HydrophobicContact CG1-CD1 3.46Å; I471-L521 VanDerWaalsContact CG1-CD1 3.46Å; I471-L521 HydrophobicContact CG1-CD2 4.04Å; I471-L521 HydrophobicContact CG1-CG 4.42Å; I517-L521 WeakPolarHBondContact O-CB 3.44Å; I517-L521 PolarHBondContact O-N 2.89Å; S518-L521 PolarHBondContact O-N 2.86Å; F519-L521 VanDerWaalsContact C-N 3.32Å; F519-L521 PolarHBondContact O-N 3.44Å; L521-F523 VanDerWaalsContact C-N 3.26Å; L521-F523 PolarHBondContact O-N 3.48Å; L521-T524 PolarHBondContact O-N 3.47Å; L521-V525 WeakPolarHBondContact O-CG2 3.48Å; L521-V525 PolarHBondContact O-N 3.39Å
522	I	86.3	Confident	85.9	Confident	103 Å²	103	59.5 Å²	59.5	53%	0.528	31%	0.311	S	S	.	.	H	α-helix	trans	-59.2	-44.4	178	-67.7	165.8	0	0	0	109.7	S518 F519 I520 V525 I526	S518-I522 WeakPolarHBondContact O-CG1 3.31Å; S518-I522 PolarHBondContact O-N 2.95Å; S518-I522 VanDerWaalsContact O-N 3.1Å; F519-I522 PolarHBondContact O-N 3.29Å; I520-I522 PolarHBondContact O-N 3.09Å; I522-V525 PolarHBondContact O-N 2.75Å; I522-I526 HydrophobicContact CG2-CD1 3.66Å; I522-I526 HydrophobicContact CG2-CG1 4.43Å; I522-I526 WeakPolarHBondContact O-CG1 3.43Å; I522-I526 PolarHBondContact O-N 3.44Å
523	F	79.9	Confident	85.4	Confident	24 Å²	24	58.1 Å²	58.1	11%	0.105	30%	0.303	C	S	.	.	H	α-helix	trans	-67.9	-42.3	-176.8	-172.9	-94.7	0	0	0	113.4	A288 K289 F519 I520 L521 V525 I526 Q527	A288-F523 HydrophobicContact CB-CD2 4.16Å; A288-F523 HydrophobicContact CB-CE2 3.26Å; A288-F523 HydrophobicContact CB-CZ 3.52Å; A288-F523 WeakPolarHBondContact O-CE1 3.42Å; A288-F523 WeakPolarHBondContact O-CZ 3.42Å; K289-F523 HydrophobicContact CB-CZ 4.32Å; K289-F523 VanDerWaalsContact N-CZ 3.27Å; F519-F523 VanDerWaalsContact O-CB 3.24Å; F519-F523 WeakPolarHBondContact O-CB 3.2Å; F519-F523 PolarHBondContact O-N 3.47Å; I520-F523 PolarHBondContact O-N 3.28Å; I520-F523 VanDerWaalsContact O-N 3.15Å; L521-F523 VanDerWaalsContact C-N 3.26Å; L521-F523 PolarHBondContact O-N 3.48Å; F523-V525 PolarHBondContact O-N 3.23Å; F523-I526 PolarHBondContact O-N 3.38Å; F523-Q527 HydrophobicContact CD1-CG 4.48Å; F523-Q527 HydrophobicContact CD2-CG 4.39Å; F523-Q527 HydrophobicContact CE1-CB 4.35Å; F523-Q527 HydrophobicContact CE1-CG 3.95Å; F523-Q527 VanDerWaalsContact CE2-CD 3.48Å; F523-Q527 HydrophobicContact CE2-CG 3.85Å; F523-Q527 HydrophobicContact CZ-CG 3.65Å; F523-Q527 PolarHBondContact O-N 2.98Å
524	T	78.1	Confident	84.9	Confident	29 Å²	29	61.2 Å²	61.2	18%	0.178	32%	0.32	C	S	.	.	H	α-helix	trans	-61.5	-34.4	176	-54.9	0	0	0	0	111.2	F467 I520 L521 Y528	F467-T524 HydrophobicContact CD1-CG2 3.95Å; F467-T524 HydrophobicContact CE1-CG2 3.54Å; F467-T524 HydrophobicContact CZ-CG2 4.05Å; I520-T524 WeakPolarHBondContact O-CB 3.21Å; I520-T524 PolarHBondContact O-N 3.42Å; I520-T524 PolarHBondContact O-OG1 3.03Å; L521-T524 PolarHBondContact O-N 3.47Å; T524-Y528 PolarHBondContact O-N 3.24Å
525	V	82.9	Confident	84.5	Confident	91 Å²	91	68.6 Å²	68.6	55%	0.552	36%	0.359	S	S	*	.	H	α-helix	trans	-71.1	-45.9	174.4	174.5	0	0	0	0	111.4	L521 I522 F523 Q527 Y528	L521-V525 WeakPolarHBondContact O-CG2 3.48Å; L521-V525 PolarHBondContact O-N 3.39Å; I522-V525 PolarHBondContact O-N 2.75Å; F523-V525 PolarHBondContact O-N 3.23Å; V525-Q527 PolarHBondContact O-N 3.03Å; V525-Y528 PolarHBondContact O-N 3Å
526	I	84.1	Confident	84.2	Confident	127 Å²	127	65.6 Å²	65.6	65%	0.651	34%	0.337	S	S	*	.	H	α-helix	trans	-64.7	-41.2	-178.5	-69.3	170	0	0	0	111.8	I522 F523 Y528	I522-I526 HydrophobicContact CG2-CD1 3.66Å; I522-I526 HydrophobicContact CG2-CG1 4.43Å; I522-I526 WeakPolarHBondContact O-CG1 3.43Å; I522-I526 PolarHBondContact O-N 3.44Å; F523-I526 PolarHBondContact O-N 3.38Å; I526-Y528 VanDerWaalsContact C-N 3.34Å
527	Q	79.4	Confident	84.2	Confident	75 Å²	75	69 Å²	69	35%	0.35	36%	0.358	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.2	16.1	-176.3	-64.8	-151.3	-7.8	0	0	114.2	F523 V525 K529	F523-Q527 HydrophobicContact CD1-CG 4.48Å; F523-Q527 HydrophobicContact CD2-CG 4.39Å; F523-Q527 HydrophobicContact CE1-CB 4.35Å; F523-Q527 HydrophobicContact CE1-CG 3.95Å; F523-Q527 VanDerWaalsContact CE2-CD 3.48Å; F523-Q527 HydrophobicContact CE2-CG 3.85Å; F523-Q527 HydrophobicContact CZ-CG 3.65Å; F523-Q527 PolarHBondContact O-N 2.98Å; V525-Q527 PolarHBondContact O-N 3.03Å; Q527-K529 PolarHBondContact O-N 3.22Å
528	Y	83.2	Confident	84.3	Confident	75 Å²	75	69.4 Å²	69.4	29%	0.294	36%	0.36	S	S	.	.			trans	-56.3	128.4	177.2	170.1	-107.4	0	0	0	110.9	Y463 F467 T524 V525 I526 F547	Y463-Y528 AromaticContact CE1-CE2 3.89Å; Y463-Y528 HydrophobicContact CE1-CE2 3.89Å; Y463-Y528 AromaticContact CZ-CE2 4Å; Y463-Y528 WeakPolarHBondContact OH-CE2 3.43Å; Y463-Y528 PolarHBondContact OH-OH 3.04Å; F467-Y528 HydrophobicContact CE2-CD2 4.23Å; F467-Y528 HydrophobicContact CE2-CE2 4.46Å; F467-Y528 AromaticContact CZ-CD2 3.69Å; F467-Y528 HydrophobicContact CZ-CD2 3.69Å; F467-Y528 HydrophobicContact CZ-CE2 4.34Å; F467-Y528 HydrophobicContact CZ-CG 4.44Å; T524-Y528 PolarHBondContact O-N 3.24Å; V525-Y528 PolarHBondContact O-N 3Å; I526-Y528 VanDerWaalsContact C-N 3.34Å; Y528-F547 HydrophobicContact CD1-CZ 4.32Å; Y528-F547 HydrophobicContact CD2-CZ 4.4Å; Y528-F547 HydrophobicContact CE1-CE2 4.09Å; Y528-F547 AromaticContact CE1-CZ 3.71Å; Y528-F547 HydrophobicContact CE1-CZ 3.71Å; Y528-F547 HydrophobicContact CE2-CE2 4.42Å; Y528-F547 AromaticContact CE2-CZ 3.77Å; Y528-F547 HydrophobicContact CE2-CZ 3.77Å; Y528-F547 AromaticContact CZ-CE2 3.7Å; Y528-F547 AromaticContact CZ-CZ 3.38Å; Y528-F547 VanDerWaalsContact OH-CE2 3.26Å; Y528-F547 WeakPolarHBondContact OH-CE2 3.36Å; Y528-F547 WeakPolarHBondContact OH-CZ 3.41Å
529	K	83.2	Confident	84.6	Confident	162 Å²	162	68.9 Å²	68.9	70%	0.704	36%	0.356	S	S	*	.			trans	-125.5	136.7	171	-69.9	-170	176.7	-168	0	108.9	Q527	Q527-K529 PolarHBondContact O-N 3.22Å
530	P	85.9	Confident	84.9	Confident	72 Å²	72	66.3 Å²	66.3	47%	0.468	36%	0.361	S	S	.	.			trans	-55.4	143.2	173.4	-24.4	34	0	0	0	111.4	L543	P530-L543 HydrophobicContact CB-CD1 4.14Å
531	I	85.9	Confident	85.4	Confident	17 Å²	17	71.9 Å²	71.9	9%	0.087	38%	0.382	C	S	.	.			trans	-68.9	148.1	176.8	64	164.1	0	0	0	110.5	L459 N462 Y463 Y538 L543	L459-I531 HydrophobicContact CB-CD1 4.25Å; L459-I531 HydrophobicContact CD1-CD1 3.67Å; N462-I531 HydrophobicContact CB-CG2 3.65Å; Y463-I531 HydrophobicContact CE2-CB 4.48Å; Y463-I531 HydrophobicContact CE2-CD1 3.97Å; Y463-I531 HydrophobicContact CE2-CG1 3.99Å; Y463-I531 HydrophobicContact CE2-CG2 3.67Å; I531-Y538 HydrophobicContact CB-CD2 4.47Å; I531-Y538 HydrophobicContact CD1-CD1 3.78Å; I531-Y538 HydrophobicContact CD1-CD2 3.84Å; I531-Y538 HydrophobicContact CD1-CE1 3.61Å; I531-Y538 HydrophobicContact CD1-CE2 3.67Å; I531-Y538 HydrophobicContact CD1-CG 3.88Å; I531-Y538 HydrophobicContact CG1-CD1 4.19Å; I531-Y538 HydrophobicContact CG1-CD2 3.58Å; I531-Y538 HydrophobicContact CG1-CE1 4.4Å; I531-Y538 HydrophobicContact CG1-CE2 3.83Å; I531-Y538 HydrophobicContact CG1-CG 3.76Å; I531-Y538 VanDerWaalsContact O-CD2 3.31Å; I531-Y538 WeakPolarHBondContact O-CD2 3.34Å; I531-L543 HydrophobicContact CG1-CD2 4.13Å
532	T	85.1	Confident	85.7	Confident	84 Å²	84	69.9 Å²	69.9	52%	0.515	37%	0.371	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-135.8	152.5	174.7	47.3	0	0	0	0	108	Y536 V537	T532-Y536 WeakPolarHBondContact CA-O 3.48Å; T532-V537 HydrophobicContact CG2-CG2 4.32Å
533	Y	83.8	Confident	86	Confident	23 Å²	23	66.2 Å²	66.2	9%	0.09	35%	0.353	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-128	106	173.8	-179.7	-115.1	0	0	0	109	W199 I206 I454 Y455 L458 D535 Y536	W199-Y533 PolarHBondContact NE1-OH 3.06Å; I206-Y533 HydrophobicContact CD1-CD1 4.34Å; I206-Y533 HydrophobicContact CD1-CE1 3.73Å; I454-Y533 HydrophobicContact CG1-CE2 4.44Å; I454-Y533 HydrophobicContact CG2-CE1 4.35Å; Y455-Y533 HydrophobicContact CD1-CD1 4.22Å; Y455-Y533 AromaticContact CE1-CD1 3.67Å; Y455-Y533 HydrophobicContact CE1-CD1 3.67Å; Y455-Y533 HydrophobicContact CE1-CG 4.37Å; L458-Y533 HydrophobicContact CD1-CD2 3.15Å; L458-Y533 HydrophobicContact CD1-CE2 3.6Å; L458-Y533 HydrophobicContact CD1-CG 3.73Å; Y533-D535 PolarHBondContact O-N 3.34Å; Y533-Y536 PolarHBondContact N-O 2.86Å; Y533-Y536 VanDerWaalsContact O-CB 3.29Å; Y533-Y536 WeakPolarHBondContact O-CB 3.37Å; Y533-Y536 PolarHBondContact O-N 2.79Å
534	N	80.9	Confident	86.7	Confident	64 Å²	64	67.9 Å²	67.9	34%	0.342	37%	0.37	S	S	.	.	T	Hydrogen-bonded Turn	trans	51.2	-124	-166.9	-55.2	-34.8	0	0	0	109.8	Y536	N534-Y536 VanDerWaalsContact C-N 3.32Å
535	D	81	Confident	87.4	Confident	165 Å²	165	69.4 Å²	69.4	88%	0.882	38%	0.377	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.8	-5.4	177.7	-57.1	-50.5	0	0	0	113.8	Y533	Y533-D535 PolarHBondContact O-N 3.34Å
536	Y	85.8	Confident	87.9	Confident	37 Å²	37	65.1 Å²	65.1	15%	0.145	35%	0.351	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.6	127.4	-178.4	175.8	-90.3	0	0	0	111.8	D209 I210 Y455 T532 Y533 N534 Y538 P539	D209-Y536 PolarHBondContact OD1-OH 3.23Å; I210-Y536 VanDerWaalsContact CG2-OH 3.27Å; I210-Y536 WeakPolarHBondContact CG2-OH 3.33Å; I210-Y536 PolarHBondContact N-OH 3.19Å; I210-Y536 VanDerWaalsContact N-OH 3.17Å; Y455-Y536 AromaticContact CD1-CD1 3.83Å; Y455-Y536 HydrophobicContact CD1-CD1 3.83Å; Y455-Y536 AromaticContact CD1-CE1 3.78Å; Y455-Y536 HydrophobicContact CD1-CE1 3.78Å; Y455-Y536 AromaticContact CE1-CD1 3.43Å; Y455-Y536 HydrophobicContact CE1-CD1 3.43Å; Y455-Y536 VanDerWaalsContact CE1-CD1 3.43Å; Y455-Y536 HydrophobicContact CE1-CD2 4.25Å; Y455-Y536 AromaticContact CE1-CE1 3.73Å; Y455-Y536 HydrophobicContact CE1-CE1 3.73Å; Y455-Y536 AromaticContact CE1-CG 3.69Å; Y455-Y536 HydrophobicContact CE1-CG 3.69Å; T532-Y536 WeakPolarHBondContact CA-O 3.48Å; Y533-Y536 PolarHBondContact N-O 2.86Å; Y533-Y536 VanDerWaalsContact O-CB 3.29Å; Y533-Y536 WeakPolarHBondContact O-CB 3.37Å; Y533-Y536 PolarHBondContact O-N 2.79Å; N534-Y536 VanDerWaalsContact C-N 3.32Å; Y536-Y538 AromaticContact CD1-CD2 3.98Å; Y536-Y538 HydrophobicContact CD1-CD2 3.98Å; Y536-Y538 HydrophobicContact CD1-CE2 4.03Å; Y536-Y538 HydrophobicContact CD1-CG 4.48Å; Y536-Y538 HydrophobicContact CE1-CD1 4.15Å; Y536-Y538 AromaticContact CE1-CD2 3.87Å; Y536-Y538 HydrophobicContact CE1-CD2 3.87Å; Y536-Y538 HydrophobicContact CE1-CE1 4.36Å; Y536-Y538 HydrophobicContact CE1-CE2 4.09Å; Y536-Y538 AromaticContact CE1-CG 3.92Å; Y536-Y538 HydrophobicContact CE1-CG 3.92Å; Y536-P539 VanDerWaalsContact OH-CD 3.31Å; Y536-P539 WeakPolarHBondContact OH-CD 3.38Å
537	V	89.7	Confident	88.2	Confident	103 Å²	103	62.8 Å²	62.8	62%	0.624	34%	0.336	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-104.4	126.4	176.5	-177.7	0	0	0	0	109.4	T532	T532-V537 HydrophobicContact CG2-CG2 4.32Å
538	Y	91.4	Very high	88.9	Confident	10 Å²	10	61.9 Å²	61.9	4%	0.039	34%	0.342	C	S	.	.			trans	-68.4	134.3	-176.7	-78.7	-106.4	0	0	0	111.8	I210 Y455 L459 I531 Y536	I210-Y538 HydrophobicContact CD1-CD1 4.12Å; I210-Y538 HydrophobicContact CD1-CE1 3.94Å; Y455-Y538 WeakPolarHBondContact CA-OH 3.24Å; Y455-Y538 HydrophobicContact CD1-CE1 4.47Å; Y455-Y538 PolarHBondContact O-OH 2.8Å; L459-Y538 HydrophobicContact CB-CE1 4.33Å; L459-Y538 HydrophobicContact CD1-CD1 4.42Å; I531-Y538 HydrophobicContact CB-CD2 4.47Å; I531-Y538 HydrophobicContact CD1-CD1 3.78Å; I531-Y538 HydrophobicContact CD1-CD2 3.84Å; I531-Y538 HydrophobicContact CD1-CE1 3.61Å; I531-Y538 HydrophobicContact CD1-CE2 3.67Å; I531-Y538 HydrophobicContact CD1-CG 3.88Å; I531-Y538 HydrophobicContact CG1-CD1 4.19Å; I531-Y538 HydrophobicContact CG1-CD2 3.58Å; I531-Y538 HydrophobicContact CG1-CE1 4.4Å; I531-Y538 HydrophobicContact CG1-CE2 3.83Å; I531-Y538 HydrophobicContact CG1-CG 3.76Å; I531-Y538 VanDerWaalsContact O-CD2 3.31Å; I531-Y538 WeakPolarHBondContact O-CD2 3.34Å; Y536-Y538 AromaticContact CD1-CD2 3.98Å; Y536-Y538 HydrophobicContact CD1-CD2 3.98Å; Y536-Y538 HydrophobicContact CD1-CE2 4.03Å; Y536-Y538 HydrophobicContact CD1-CG 4.48Å; Y536-Y538 HydrophobicContact CE1-CD1 4.15Å; Y536-Y538 AromaticContact CE1-CD2 3.87Å; Y536-Y538 HydrophobicContact CE1-CD2 3.87Å; Y536-Y538 HydrophobicContact CE1-CE1 4.36Å; Y536-Y538 HydrophobicContact CE1-CE2 4.09Å; Y536-Y538 AromaticContact CE1-CG 3.92Å; Y536-Y538 HydrophobicContact CE1-CG 3.92Å
539	P	93.4	Very high	89.3	Confident	31 Å²	31	59.4 Å²	59.4	20%	0.201	33%	0.333	C	S	.	.			trans	-68.2	150	178.4	28.3	-35.5	0	0	0	111.1	I210 Y536 W541 S542 L543	I210-P539 HydrophobicContact CG2-CG 3.76Å; Y536-P539 VanDerWaalsContact OH-CD 3.31Å; Y536-P539 WeakPolarHBondContact OH-CD 3.38Å; P539-W541 VanDerWaalsContact C-N 3.25Å; P539-W541 HydrophobicContact CG-CD2 4.45Å; P539-W541 HydrophobicContact CG-CZ2 4.04Å; P539-W541 VanDerWaalsContact CG-NE1 3.31Å; P539-W541 PolarHBondContact O-N 2.96Å; P539-W541 VanDerWaalsContact O-N 3.12Å; P539-S542 WeakPolarHBondContact CD-OG 3.2Å; P539-S542 WeakPolarHBondContact O-CB 3.4Å; P539-S542 PolarHBondContact O-N 3.15Å; P539-S542 PolarHBondContact O-OG 3.16Å; P539-L543 PolarHBondContact O-N 3.16Å
540	G	93.1	Very high	89.6	Confident	57 Å²	57	52 Å²	52	59%	0.588	30%	0.302	S	S	*	.	H	α-helix	trans	-56.3	-32.4	-174.6	0	0	0	0	0	115.3	S542 L543 A544	G540-S542 VanDerWaalsContact C-N 3.34Å; G540-S542 PolarHBondContact O-N 3.4Å; G540-L543 PolarHBondContact O-N 3.4Å; G540-A544 PolarHBondContact O-N 3.15Å
541	W	94.3	Very high	89.9	Confident	118 Å²	118	53.6 Å²	53.6	45%	0.447	31%	0.306	S	S	.	.	H	α-helix	trans	-66.6	-35.6	176.1	67.6	-98.8	0	0	0	112.1	I210 W456 P539 A544 I545	I210-W541 HydrophobicContact CG2-CH2 3.74Å; I210-W541 HydrophobicContact CG2-CZ2 3.55Å; W456-W541 HydrophobicContact CH2-CZ3 4.19Å; W456-W541 HydrophobicContact CZ2-CH2 4.29Å; W456-W541 HydrophobicContact CZ2-CZ3 4.31Å; P539-W541 VanDerWaalsContact C-N 3.25Å; P539-W541 HydrophobicContact CG-CD2 4.45Å; P539-W541 HydrophobicContact CG-CZ2 4.04Å; P539-W541 VanDerWaalsContact CG-NE1 3.31Å; P539-W541 PolarHBondContact O-N 2.96Å; P539-W541 VanDerWaalsContact O-N 3.12Å; W541-A544 WeakPolarHBondContact O-CB 3.4Å; W541-A544 PolarHBondContact O-N 2.94Å; W541-I545 HydrophobicContact CE3-CD1 3.58Å; W541-I545 HydrophobicContact CE3-CG1 4.5Å; W541-I545 HydrophobicContact CZ3-CD1 3.58Å; W541-I545 WeakPolarHBondContact O-CG1 3.39Å; W541-I545 PolarHBondContact O-N 2.9Å
542	S	93.1	Very high	90.3	Very high	0 Å²	0	54.5 Å²	54.5	0%	0	31%	0.314	C	S	.	.	H	α-helix	trans	-70.2	-36.9	177.7	70.8	0	0	0	0	111.3	P539 G540 A544 I545 G546	P539-S542 WeakPolarHBondContact CD-OG 3.2Å; P539-S542 WeakPolarHBondContact O-CB 3.4Å; P539-S542 PolarHBondContact O-N 3.15Å; P539-S542 PolarHBondContact O-OG 3.16Å; G540-S542 VanDerWaalsContact C-N 3.34Å; G540-S542 PolarHBondContact O-N 3.4Å; S542-A544 VanDerWaalsContact C-N 3.34Å; S542-A544 PolarHBondContact O-N 3.42Å; S542-I545 WeakPolarHBondContact O-CB 3.43Å; S542-I545 PolarHBondContact O-N 3.3Å; S542-G546 PolarHBondContact O-N 3.05Å
543	L	92.3	Very high	90.6	Very high	27 Å²	27	50.5 Å²	50.5	14%	0.141	29%	0.289	C	S	.	.	H	α-helix	trans	-63.2	-40.2	171.3	-58.2	178	0	0	0	111.4	Y463 P530 I531 P539 G540 I545 G546 F547	Y463-L543 HydrophobicContact CE2-CD2 4.44Å; Y463-L543 WeakPolarHBondContact OH-CD2 3.31Å; P530-L543 HydrophobicContact CB-CD1 4.14Å; I531-L543 HydrophobicContact CG1-CD2 4.13Å; P539-L543 PolarHBondContact O-N 3.16Å; G540-L543 PolarHBondContact O-N 3.4Å; L543-I545 VanDerWaalsContact C-N 3.31Å; L543-I545 PolarHBondContact O-N 3.05Å; L543-G546 PolarHBondContact O-N 3.04Å; L543-F547 VanDerWaalsContact O-CD2 3.27Å; L543-F547 WeakPolarHBondContact O-CD2 3.29Å; L543-F547 PolarHBondContact O-N 3.48Å
544	A	93.6	Very high	91.1	Very high	58 Å²	58	50.7 Å²	50.7	48%	0.479	29%	0.293	S	S	.	.	H	α-helix	trans	-61.8	-39.3	174.7	0	0	0	0	0	111.9	G540 W541 S542 F547 A548	G540-A544 PolarHBondContact O-N 3.15Å; W541-A544 WeakPolarHBondContact O-CB 3.4Å; W541-A544 PolarHBondContact O-N 2.94Å; S542-A544 VanDerWaalsContact C-N 3.34Å; S542-A544 PolarHBondContact O-N 3.42Å; A544-F547 PolarHBondContact O-N 2.64Å; A544-A548 WeakPolarHBondContact O-CB 3.41Å; A544-A548 PolarHBondContact O-N 3.49Å
545	I	93.8	Very high	91.7	Very high	62 Å²	62	51.8 Å²	51.8	32%	0.318	30%	0.298	S	S	.	.	H	α-helix	trans	-63.5	-44.7	171.9	-66.1	173.3	0	0	0	110.8	W456 W541 S542 L543 F547 A548 M549	W456-I545 HydrophobicContact CH2-CD1 4.03Å; W456-I545 HydrophobicContact CZ3-CG2 4.19Å; W541-I545 HydrophobicContact CE3-CD1 3.58Å; W541-I545 HydrophobicContact CE3-CG1 4.5Å; W541-I545 HydrophobicContact CZ3-CD1 3.58Å; W541-I545 WeakPolarHBondContact O-CG1 3.39Å; W541-I545 PolarHBondContact O-N 2.9Å; S542-I545 WeakPolarHBondContact O-CB 3.43Å; S542-I545 PolarHBondContact O-N 3.3Å; L543-I545 VanDerWaalsContact C-N 3.31Å; L543-I545 PolarHBondContact O-N 3.05Å; I545-F547 PolarHBondContact O-N 3.05Å; I545-A548 CarbonylContact O-C 3.6Å; I545-A548 WeakPolarHBondContact O-CB 3.4Å; I545-A548 PolarHBondContact O-N 3.22Å; I545-A548 VanDerWaalsContact O-N 3.12Å; I545-M549 HydrophobicContact CG2-CG 4.47Å; I545-M549 WeakPolarHBondContact O-CG 3.41Å; I545-M549 PolarHBondContact O-N 3.29Å
546	G	92.1	Very high	92.3	Very high	0 Å²	0	45.3 Å²	45.3	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-56	-47.4	175.3	0	0	0	0	0	112.3	Y463 S542 L543 A548 M549 A550	Y463-G546 WeakPolarHBondContact CB-O 3.43Å; S542-G546 PolarHBondContact O-N 3.05Å; L543-G546 PolarHBondContact O-N 3.04Å; G546-A548 PolarHBondContact O-N 3.29Å; G546-M549 WeakPolarHBondContact O-CB 3.23Å; G546-M549 PolarHBondContact O-N 3.49Å; G546-A550 PolarHBondContact O-N 3.39Å
547	F	91.8	Very high	92.7	Very high	78 Å²	78	44.1 Å²	44.1	34%	0.342	26%	0.261	S	S	.	.	H	α-helix	trans	-64.8	-38.5	174.2	-79.6	-66.3	0	0	0	113	Y463 Y528 L543 A544 I545 M549 A550 L551	Y463-F547 HydrophobicContact CE1-CD1 4.41Å; Y463-F547 HydrophobicContact CE1-CD2 4.27Å; Y463-F547 HydrophobicContact CE1-CE1 4.22Å; Y463-F547 HydrophobicContact CE1-CE2 4.08Å; Y463-F547 HydrophobicContact CE1-CG 4.43Å; Y463-F547 HydrophobicContact CE1-CZ 4.06Å; Y528-F547 HydrophobicContact CD1-CZ 4.32Å; Y528-F547 HydrophobicContact CD2-CZ 4.4Å; Y528-F547 HydrophobicContact CE1-CE2 4.09Å; Y528-F547 AromaticContact CE1-CZ 3.71Å; Y528-F547 HydrophobicContact CE1-CZ 3.71Å; Y528-F547 HydrophobicContact CE2-CE2 4.42Å; Y528-F547 AromaticContact CE2-CZ 3.77Å; Y528-F547 HydrophobicContact CE2-CZ 3.77Å; Y528-F547 AromaticContact CZ-CE2 3.7Å; Y528-F547 AromaticContact CZ-CZ 3.38Å; Y528-F547 VanDerWaalsContact OH-CE2 3.26Å; Y528-F547 WeakPolarHBondContact OH-CE2 3.36Å; Y528-F547 WeakPolarHBondContact OH-CZ 3.41Å; L543-F547 VanDerWaalsContact O-CD2 3.27Å; L543-F547 WeakPolarHBondContact O-CD2 3.29Å; L543-F547 PolarHBondContact O-N 3.48Å; A544-F547 PolarHBondContact O-N 2.64Å; I545-F547 PolarHBondContact O-N 3.05Å; F547-M549 VanDerWaalsContact C-N 3.3Å; F547-M549 PolarHBondContact O-N 2.94Å; F547-A550 PolarHBondContact O-N 3.09Å; F547-L551 WeakPolarHBondContact O-CB 3.32Å; F547-L551 VanDerWaalsContact O-CG 3.25Å; F547-L551 WeakPolarHBondContact O-CG 3.49Å; F547-L551 PolarHBondContact O-N 3.02Å
548	A	93.3	Very high	92.9	Very high	57 Å²	57	42.4 Å²	42.4	47%	0.471	25%	0.252	S	S	.	.	H	α-helix	trans	-61.7	-39	174.6	0	0	0	0	0	111.6	A544 I545 G546 L551 S552	A544-A548 WeakPolarHBondContact O-CB 3.41Å; A544-A548 PolarHBondContact O-N 3.49Å; I545-A548 CarbonylContact O-C 3.6Å; I545-A548 WeakPolarHBondContact O-CB 3.4Å; I545-A548 PolarHBondContact O-N 3.22Å; I545-A548 VanDerWaalsContact O-N 3.12Å; G546-A548 PolarHBondContact O-N 3.29Å; A548-L551 PolarHBondContact O-N 3.48Å; A548-S552 WeakPolarHBondContact O-CB 3.22Å; A548-S552 PolarHBondContact O-N 3.26Å
549	M	91.9	Very high	93.1	Very high	22 Å²	22	46.8 Å²	46.8	11%	0.108	28%	0.275	C	S	.	.	H	α-helix	trans	-61.8	-48.9	173.2	-71.1	-178.8	73.4	0	0	111.7	Y119 M460 A464 I545 G546 F547 L551 S552	Y119-M549 HydrophobicContact CD1-CE 3.76Å; Y119-M549 HydrophobicContact CD2-CE 4.26Å; Y119-M549 HydrophobicContact CE1-CE 3.96Å; Y119-M549 HydrophobicContact CE2-CE 4.42Å; Y119-M549 HydrophobicContact CG-CE 3.93Å; M460-M549 HydrophobicContact CB-CE 4.22Å; M460-M549 HydrophobicContact CE-CE 3.8Å; M460-M549 HydrophobicContact CG-CE 3.62Å; M460-M549 HydrophobicContact CG-SD 4.15Å; M460-M549 HydrophobicContact SD-CE 4.33Å; A464-M549 HydrophobicContact CB-CE 4Å; I545-M549 HydrophobicContact CG2-CG 4.47Å; I545-M549 WeakPolarHBondContact O-CG 3.41Å; I545-M549 PolarHBondContact O-N 3.29Å; G546-M549 WeakPolarHBondContact O-CB 3.23Å; G546-M549 PolarHBondContact O-N 3.49Å; F547-M549 VanDerWaalsContact C-N 3.3Å; F547-M549 PolarHBondContact O-N 2.94Å; M549-L551 PolarHBondContact O-N 3.21Å; M549-S552 PolarHBondContact O-N 3.25Å; M549-S552 PolarHBondContact O-OG 3.2Å
550	A	90.1	Very high	93	Very high	6 Å²	6	47.6 Å²	47.6	5%	0.05	27%	0.274	C	S	.	.	H	α-helix	trans	-58.1	-50.1	176.6	0	0	0	0	0	111	Y463 F467 S468 G546 F547 S552 S553	Y463-A550 WeakPolarHBondContact O-CB 3.41Å; F467-A550 HydrophobicContact CB-CB 4.47Å; S468-A550 WeakPolarHBondContact OG-CA 3.44Å; S468-A550 PolarHBondContact OG-O 3.32Å; G546-A550 PolarHBondContact O-N 3.39Å; F547-A550 PolarHBondContact O-N 3.09Å; A550-S552 VanDerWaalsContact C-N 3.29Å; A550-S552 PolarHBondContact O-N 2.78Å; A550-S553 PolarHBondContact O-N 3.3Å; A550-S553 PolarHBondContact O-OG 2.84Å
551	L	91.6	Very high	93	Very high	107 Å²	107	45.1 Å²	45.1	56%	0.56	25%	0.249	S	C	*	.	H	α-helix	trans	-63.3	-31.9	179.7	-70.8	172.3	0	0	0	112.9	F547 A548 M549 S553 V554 I555	F547-L551 WeakPolarHBondContact O-CB 3.32Å; F547-L551 VanDerWaalsContact O-CG 3.25Å; F547-L551 WeakPolarHBondContact O-CG 3.49Å; F547-L551 PolarHBondContact O-N 3.02Å; A548-L551 PolarHBondContact O-N 3.48Å; M549-L551 PolarHBondContact O-N 3.21Å; L551-S553 PolarHBondContact O-N 3.05Å; L551-V554 PolarHBondContact O-N 3.37Å; L551-V554 VanDerWaalsContact O-N 3.11Å; L551-I555 VanDerWaalsContact O-CB 3.27Å; L551-I555 WeakPolarHBondContact O-CB 3.22Å; L551-I555 VanDerWaalsContact O-CG2 3.31Å; L551-I555 WeakPolarHBondContact O-CG2 3.48Å; L551-I555 PolarHBondContact O-N 2.7Å
552	S	93.9	Very high	92.9	Very high	35 Å²	35	45.3 Å²	45.3	25%	0.245	26%	0.258	C	S	.	.	H	α-helix	trans	-58	-35.5	-179.4	73.1	0	0	0	0	113.1	Y119 A548 M549 A550 I555 C556	Y119-S552 WeakPolarHBondContact CE2-OG 3.38Å; Y119-S552 PolarHBondContact OH-OG 2.85Å; A548-S552 WeakPolarHBondContact O-CB 3.22Å; A548-S552 PolarHBondContact O-N 3.26Å; M549-S552 PolarHBondContact O-N 3.25Å; M549-S552 PolarHBondContact O-OG 3.2Å; A550-S552 VanDerWaalsContact C-N 3.29Å; A550-S552 PolarHBondContact O-N 2.78Å; S552-I555 WeakPolarHBondContact O-CG2 3.42Å; S552-C556 PolarHBondContact O-SG 3.22Å
553	S	92.7	Very high	92.9	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-77.5	-38.6	174.4	58.1	0	0	0	0	113.5	G112 S468 A550 L551 C556	G112-S553 VanDerWaalsContact CA-O 3.27Å; G112-S553 WeakPolarHBondContact CA-O 3.29Å; S468-S553 WeakPolarHBondContact CB-OG 3.41Å; S468-S553 PolarHBondContact OG-OG 2.96Å; A550-S553 PolarHBondContact O-N 3.3Å; A550-S553 PolarHBondContact O-OG 2.84Å; L551-S553 PolarHBondContact O-N 3.05Å; S553-C556 WeakPolarHBondContact O-CB 3.25Å
554	V	92.6	Very high	92.8	Very high	27 Å²	27	51.7 Å²	51.7	16%	0.164	28%	0.283	C	S	.	.	H	α-helix	trans	-75.3	-36.5	-175.7	177.5	0	0	0	0	111.2	I471 L551 C556 I557 P558	I471-V554 HydrophobicContact CB-CG2 4.32Å; I471-V554 HydrophobicContact CD1-CG1 4.35Å; I471-V554 HydrophobicContact CD1-CG2 3.98Å; I471-V554 HydrophobicContact CG2-CG1 3.86Å; I471-V554 HydrophobicContact CG2-CG2 4.28Å; L551-V554 PolarHBondContact O-N 3.37Å; L551-V554 VanDerWaalsContact O-N 3.11Å; V554-C556 PolarHBondContact O-N 2.94Å; V554-I557 WeakPolarHBondContact O-CB 3.41Å; V554-I557 WeakPolarHBondContact O-CG1 3.36Å; V554-I557 PolarHBondContact O-N 3.35Å; V554-I557 VanDerWaalsContact O-N 3.09Å; V554-P558 WeakPolarHBondContact O-CD 3.39Å
555	I	94.4	Very high	92.6	Very high	87 Å²	87	49.9 Å²	49.9	45%	0.446	27%	0.265	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.8	-21.7	-177.9	-154.9	174.9	0	0	0	112.6	L551 S552 I557 P558 I559	L551-I555 VanDerWaalsContact O-CB 3.27Å; L551-I555 WeakPolarHBondContact O-CB 3.22Å; L551-I555 VanDerWaalsContact O-CG2 3.31Å; L551-I555 WeakPolarHBondContact O-CG2 3.48Å; L551-I555 PolarHBondContact O-N 2.7Å; S552-I555 WeakPolarHBondContact O-CG2 3.42Å; I555-I557 PolarHBondContact O-N 2.9Å; I555-P558 HydrophobicContact CG1-CG 4.41Å; I555-P558 WeakPolarHBondContact O-CD 3.32Å; I555-P558 WeakPolarHBondContact O-CG 3.32Å; I555-I559 HydrophobicContact CB-CD1 4.36Å; I555-I559 HydrophobicContact CD1-CD1 4.08Å; I555-I559 HydrophobicContact CG1-CD1 3.73Å; I555-I559 HydrophobicContact CG1-CG1 4.08Å; I555-I559 HydrophobicContact CG2-CD1 4.05Å; I555-I559 WeakPolarHBondContact O-CB 3.32Å; I555-I559 VanDerWaalsContact O-CG1 3.24Å; I555-I559 WeakPolarHBondContact O-CG1 3.3Å; I555-I559 PolarHBondContact O-N 3.26Å; I555-I559 VanDerWaalsContact O-N 3.09Å
556	C	93.9	Very high	92.4	Very high	29 Å²	29	50 Å²	50	20%	0.196	27%	0.271	C	S	.	.	H	α-helix	trans	-55.7	-32.6	171.2	-64.4	0	0	0	0	112.3	G108 S552 S553 V554 Y560	G108-C556 WeakPolarHBondContact CA-O 3.29Å; S552-C556 PolarHBondContact O-SG 3.22Å; S553-C556 WeakPolarHBondContact O-CB 3.25Å; V554-C556 PolarHBondContact O-N 2.94Å; C556-Y560 VanDerWaalsContact O-CB 3.25Å; C556-Y560 WeakPolarHBondContact O-CB 3.11Å; C556-Y560 PolarHBondContact O-N 3.08Å; C556-Y560 VanDerWaalsContact O-N 3.07Å
557	I	93.7	Very high	92.2	Very high	13 Å²	13	58.5 Å²	58.5	7%	0.067	30%	0.304	C	S	.	.	H	α-helix	trans	-66	-61	-178.7	-53.9	171.8	0	0	0	111.5	F106 V109 I472 I475 V554 I555 G561	F106-I557 HydrophobicContact CD1-CG2 4.3Å; V109-I557 HydrophobicContact CG2-CD1 3.98Å; V109-I557 HydrophobicContact CG2-CG1 3.99Å; V109-I557 HydrophobicContact CG2-CG2 4.2Å; I472-I557 HydrophobicContact CG1-CD1 4.37Å; I475-I557 HydrophobicContact CD1-CD1 3.56Å; I475-I557 HydrophobicContact CD1-CG2 4.34Å; I475-I557 HydrophobicContact CG2-CG2 4.49Å; V554-I557 WeakPolarHBondContact O-CB 3.41Å; V554-I557 WeakPolarHBondContact O-CG1 3.36Å; V554-I557 PolarHBondContact O-N 3.35Å; V554-I557 VanDerWaalsContact O-N 3.09Å; I555-I557 PolarHBondContact O-N 2.9Å; I557-G561 PolarHBondContact O-N 3.4Å
558	P	94.4	Very high	91.8	Very high	67 Å²	67	55 Å²	55	44%	0.435	29%	0.289	S	S	.	.	H	α-helix	trans	-65.8	-38	178.7	26.1	-35	0	0	0	112.7	V554 I555 Y560 G561 L562	V554-P558 WeakPolarHBondContact O-CD 3.39Å; I555-P558 HydrophobicContact CG1-CG 4.41Å; I555-P558 WeakPolarHBondContact O-CD 3.32Å; I555-P558 WeakPolarHBondContact O-CG 3.32Å; P558-Y560 PolarHBondContact O-N 3.24Å; P558-G561 PolarHBondContact O-N 3.48Å; P558-L562 WeakPolarHBondContact O-CB 3.22Å; P558-L562 VanDerWaalsContact O-CG 3.31Å; P558-L562 WeakPolarHBondContact O-CG 3.17Å; P558-L562 PolarHBondContact O-N 3Å
559	I	94.3	Very high	91.3	Very high	102 Å²	102	57 Å²	57	52%	0.523	30%	0.297	S	S	.	.	H	α-helix	trans	-59.5	-50.6	179.1	-70.5	172.2	0	0	0	110.5	I555 G561 L562 Y563	I555-I559 HydrophobicContact CB-CD1 4.36Å; I555-I559 HydrophobicContact CD1-CD1 4.08Å; I555-I559 HydrophobicContact CG1-CD1 3.73Å; I555-I559 HydrophobicContact CG1-CG1 4.08Å; I555-I559 HydrophobicContact CG2-CD1 4.05Å; I555-I559 WeakPolarHBondContact O-CB 3.32Å; I555-I559 VanDerWaalsContact O-CG1 3.24Å; I555-I559 WeakPolarHBondContact O-CG1 3.3Å; I555-I559 PolarHBondContact O-N 3.26Å; I555-I559 VanDerWaalsContact O-N 3.09Å; I559-G561 VanDerWaalsContact C-N 3.34Å; I559-G561 PolarHBondContact O-N 2.7Å; I559-L562 PolarHBondContact O-N 3.42Å; I559-Y563 WeakPolarHBondContact O-CB 3.47Å; I559-Y563 PolarHBondContact O-N 3.08Å
560	Y	93.1	Very high	90.7	Very high	47 Å²	47	57.6 Å²	57.6	18%	0.184	31%	0.308	C	S	.	.	H	α-helix	trans	-67.8	-37.1	179.6	-165.5	-81.8	0	0	0	111.7	P104 K107 Y111 C556 P558 Y563 K564	P104-Y560 VanDerWaalsContact O-CE1 3.24Å; P104-Y560 WeakPolarHBondContact O-CE1 3.38Å; K107-Y560 HydrophobicContact CB-CD1 3.75Å; K107-Y560 HydrophobicContact CB-CE1 3.45Å; K107-Y560 VanDerWaalsContact CB-CE1 3.45Å; K107-Y560 HydrophobicContact CB-CG 4.44Å; K107-Y560 HydrophobicContact CD-CE1 4.13Å; K107-Y560 HydrophobicContact CD-CE2 4.2Å; K107-Y560 WeakPolarHBondContact CD-OH 3.4Å; K107-Y560 HydrophobicContact CG-CE1 4.29Å; Y111-Y560 HydrophobicContact CD2-CD2 4.21Å; Y111-Y560 AromaticContact CE2-CD2 3.85Å; Y111-Y560 HydrophobicContact CE2-CD2 3.85Å; Y111-Y560 AromaticContact CE2-CE2 3.87Å; Y111-Y560 HydrophobicContact CE2-CE2 3.87Å; C556-Y560 VanDerWaalsContact O-CB 3.25Å; C556-Y560 WeakPolarHBondContact O-CB 3.11Å; C556-Y560 PolarHBondContact O-N 3.08Å; C556-Y560 VanDerWaalsContact O-N 3.07Å; P558-Y560 PolarHBondContact O-N 3.24Å; Y560-Y563 HydrophobicContact CE2-CD1 4.33Å; Y560-Y563 PolarHBondContact O-N 3.36Å; Y560-K564 HydrophobicContact CD1-CB 4.43Å; Y560-K564 HydrophobicContact CE1-CB 4.22Å; Y560-K564 WeakPolarHBondContact O-CB 3.42Å; Y560-K564 PolarHBondContact O-N 3.32Å
561	G	92.1	Very high	90.2	Very high	6 Å²	6	62.2 Å²	62.2	6%	0.062	35%	0.347	C	S	.	.	H	α-helix	trans	-58.9	-50.2	175.4	0	0	0	0	0	112.3	M105 I557 P558 I559 K564 I565	M105-G561 WeakPolarHBondContact O-CA 3.49Å; I557-G561 PolarHBondContact O-N 3.4Å; P558-G561 PolarHBondContact O-N 3.48Å; I559-G561 VanDerWaalsContact C-N 3.34Å; I559-G561 PolarHBondContact O-N 2.7Å; G561-K564 PolarHBondContact O-N 3.08Å; G561-I565 VanDerWaalsContact O-CG1 3.25Å; G561-I565 WeakPolarHBondContact O-CG1 3.32Å; G561-I565 PolarHBondContact O-N 3.31Å
562	L	92.2	Very high	90	Very high	121 Å²	121	60.4 Å²	60.4	63%	0.634	34%	0.34	S	S	*	.	H	α-helix	trans	-62.2	-45.4	176.9	-70.9	173.8	0	0	0	111.6	P558 I559 K564 I565 S566	P558-L562 WeakPolarHBondContact O-CB 3.22Å; P558-L562 VanDerWaalsContact O-CG 3.31Å; P558-L562 WeakPolarHBondContact O-CG 3.17Å; P558-L562 PolarHBondContact O-N 3Å; I559-L562 PolarHBondContact O-N 3.42Å; L562-K564 VanDerWaalsContact C-N 3.32Å; L562-K564 PolarHBondContact O-N 3.39Å; L562-I565 PolarHBondContact O-N 3.5Å; L562-S566 WeakPolarHBondContact O-CB 3.35Å; L562-S566 PolarHBondContact O-N 3.17Å; L562-S566 PolarHBondContact O-OG 2.89Å
563	Y	92.7	Very high	89.6	Confident	104 Å²	104	65.4 Å²	65.4	41%	0.408	36%	0.358	S	S	.	.	H	α-helix	trans	-55.6	-47.2	173.8	169.2	-107.5	0	0	0	111.3	I559 Y560 S566 R567	I559-Y563 WeakPolarHBondContact O-CB 3.47Å; I559-Y563 PolarHBondContact O-N 3.08Å; Y560-Y563 HydrophobicContact CE2-CD1 4.33Å; Y560-Y563 PolarHBondContact O-N 3.36Å; Y563-S566 PolarHBondContact O-N 3.09Å; Y563-S566 PolarHBondContact O-OG 3Å; Y563-R567 HydrophobicContact CE2-CG 4.34Å; Y563-R567 PolarHBondContact O-N 2.94Å; Y563-R567 PolarHBondContact OH-NH1 3.01Å; Y563-R567 VanDerWaalsContact OH-NH1 3.16Å
564	K	90.5	Very high	89.3	Confident	57 Å²	57	75.5 Å²	75.5	25%	0.248	40%	0.396	C	S	.	.	H	α-helix	trans	-67.7	-43.3	-178.1	-171.3	57.5	179	173.8	0	112.2	P104 Y560 G561 L562 S566 R567 S568 A580	P104-K564 HydrophobicContact CB-CD 4.41Å; P104-K564 HydrophobicContact CB-CG 4.24Å; Y560-K564 HydrophobicContact CD1-CB 4.43Å; Y560-K564 HydrophobicContact CE1-CB 4.22Å; Y560-K564 WeakPolarHBondContact O-CB 3.42Å; Y560-K564 PolarHBondContact O-N 3.32Å; G561-K564 PolarHBondContact O-N 3.08Å; L562-K564 VanDerWaalsContact C-N 3.32Å; L562-K564 PolarHBondContact O-N 3.39Å; K564-S566 VanDerWaalsContact C-N 3.3Å; K564-S566 PolarHBondContact O-N 2.89Å; K564-R567 PolarHBondContact O-N 3.49Å; K564-S568 PolarHBondContact O-N 3.4Å; K564-S568 PolarHBondContact O-OG 2.87Å; K564-A580 HydrophobicContact CG-CB 4.32Å
565	I	89.9	Confident	89	Confident	20 Å²	20	78.3 Å²	78.3	10%	0.103	41%	0.407	C	S	.	.	H	α-helix	trans	-60.2	-42.4	175.7	-66.7	163.4	0	0	0	110.5	M105 G561 L562 R567 S568 F573 R576 L577 A580	M105-I565 HydrophobicContact SD-CD1 4.01Å; M105-I565 HydrophobicContact SD-CG1 4.4Å; G561-I565 VanDerWaalsContact O-CG1 3.25Å; G561-I565 WeakPolarHBondContact O-CG1 3.32Å; G561-I565 PolarHBondContact O-N 3.31Å; L562-I565 PolarHBondContact O-N 3.5Å; I565-R567 PolarHBondContact O-N 2.92Å; I565-S568 PolarHBondContact O-N 3.17Å; I565-F573 HydrophobicContact CG2-CD2 4.2Å; I565-F573 HydrophobicContact CG2-CE2 3.8Å; I565-R576 HydrophobicContact CG2-CB 4.27Å; I565-R576 PolarHBondContact O-NE 2.82Å; I565-L577 HydrophobicContact CD1-CD1 3.9Å; I565-L577 HydrophobicContact CG1-CD1 4.36Å; I565-A580 HydrophobicContact CG1-CB 3.98Å
566	S	88.6	Confident	88.7	Confident	65 Å²	65	78 Å²	78	46%	0.455	40%	0.401	S	S	.	.	H	α-helix	trans	-66.5	-19.9	-179.8	77.4	0	0	0	0	114.4	L562 Y563 K564 R576	L562-S566 WeakPolarHBondContact O-CB 3.35Å; L562-S566 PolarHBondContact O-N 3.17Å; L562-S566 PolarHBondContact O-OG 2.89Å; Y563-S566 PolarHBondContact O-N 3.09Å; Y563-S566 PolarHBondContact O-OG 3Å; K564-S566 VanDerWaalsContact C-N 3.3Å; K564-S566 PolarHBondContact O-N 2.89Å; S566-R576 VanDerWaalsContact C-NH2 3.34Å; S566-R576 PolarHBondContact O-NH2 3.24Å
567	R	87.7	Confident	88.4	Confident	179 Å²	179	79.6 Å²	79.6	68%	0.675	41%	0.407	S	S	*	.	H	α-helix	trans	-107.9	-8.1	176.4	-76.7	-159.1	173.2	-172.5	-0.9	114.2	Y563 K564 I565	Y563-R567 HydrophobicContact CE2-CG 4.34Å; Y563-R567 PolarHBondContact O-N 2.94Å; Y563-R567 PolarHBondContact OH-NH1 3.01Å; Y563-R567 VanDerWaalsContact OH-NH1 3.16Å; K564-R567 PolarHBondContact O-N 3.49Å; I565-R567 PolarHBondContact O-N 2.92Å
568	S	85.4	Confident	88	Confident	5 Å²	5	85.7 Å²	85.7	4%	0.035	43%	0.433	C	S	.	.	S	Bend	trans	-67	140.2	176.1	-75.2	0	0	0	0	110.6	K564 I565 R576	K564-S568 PolarHBondContact O-N 3.4Å; K564-S568 PolarHBondContact O-OG 2.87Å; I565-S568 PolarHBondContact O-N 3.17Å; S568-R576 PolarHBondContact O-NE 3.31Å; S568-R576 PolarHBondContact O-NH2 2.98Å
569	P	80.8	Confident	87.6	Confident	98 Å²	98	86.6 Å²	86.6	64%	0.636	43%	0.431	S	S	*	.			trans	-67.2	144.2	172	29.8	-33.7	0	0	0	109.9	H579	P569-H579 PolarHBondContact O-CD2 2.92Å
570	G	79.8	Confident	87.2	Confident	34 Å²	34	81.8 Å²	81.8	35%	0.351	41%	0.406	S	S	.	.			trans	148.2	138.4	179.9	0	0	0	0	0	111.1	R576	G570-R576 WeakPolarHBondContact O-CD 3.13Å; G570-R576 WeakPolarHBondContact O-CG 3.12Å
571	A	79.5	Confident	86.9	Confident	104 Å²	104	80.8 Å²	80.8	86%	0.86	41%	0.406	S	S	*	.	S	Bend	trans	-78.9	-30.3	-179.3	0	0	0	0	0	111.2	E575	A571-E575 PolarHBondContact N-OE2 3.26Å
572	T	87.9	Confident	86.7	Confident	69 Å²	69	84.9 Å²	84.9	42%	0.423	42%	0.423	S	S	.	.	S	Bend	trans	-109.5	152	179	65.5	0	0	0	0	112.2	R574 E575 R576	T572-R574 PolarHBondContact O-N 3.41Å; T572-E575 PolarHBondContact N-OE2 3.17Å; T572-E575 PolarHBondContact O-N 3.46Å; T572-E575 VanDerWaalsContact O-N 3.16Å; T572-E575 VanDerWaalsContact OG1-CG 3.3Å; T572-E575 WeakPolarHBondContact OG1-CG 3.46Å; T572-E575 PolarHBondContact OG1-N 2.84Å; T572-R576 WeakPolarHBondContact O-CG 3.3Å; T572-R576 PolarHBondContact O-N 2.87Å; T572-R576 VanDerWaalsContact O-N 3.07Å
573	F	86.1	Confident	86.4	Confident	140 Å²	140	81 Å²	81	61%	0.614	41%	0.409	S	S	*	.	H	α-helix	trans	-54.9	-37.6	174.4	180	-98.7	0	0	0	112.3	I565 R576 L577	I565-F573 HydrophobicContact CG2-CD2 4.2Å; I565-F573 HydrophobicContact CG2-CE2 3.8Å; F573-R576 PolarHBondContact O-N 3.05Å; F573-L577 HydrophobicContact CE1-CD2 4.33Å; F573-L577 WeakPolarHBondContact O-CB 3.41Å; F573-L577 PolarHBondContact O-N 3.31Å
574	R	85.2	Confident	86.1	Confident	212 Å²	212	79.6 Å²	79.6	80%	0.8	41%	0.406	S	S	*	.	H	α-helix	trans	-65	-40.3	179.4	-169.8	177.5	-179	178	0.5	112.5	T572 K578	T572-R574 PolarHBondContact O-N 3.41Å; R574-K578 WeakPolarHBondContact O-CB 3.35Å; R574-K578 PolarHBondContact O-N 2.99Å
575	E	86.7	Confident	85.7	Confident	85 Å²	85	82.9 Å²	82.9	40%	0.397	43%	0.433	S	S	.	.	H	α-helix	trans	-65.6	-46.4	173.9	-75.7	164.8	-173.7	0	0	111.3	A571 T572 L577 K578 H579	A571-E575 PolarHBondContact N-OE2 3.26Å; T572-E575 PolarHBondContact N-OE2 3.17Å; T572-E575 PolarHBondContact O-N 3.46Å; T572-E575 VanDerWaalsContact O-N 3.16Å; T572-E575 VanDerWaalsContact OG1-CG 3.3Å; T572-E575 WeakPolarHBondContact OG1-CG 3.46Å; T572-E575 PolarHBondContact OG1-N 2.84Å; E575-L577 VanDerWaalsContact C-N 3.3Å; E575-L577 PolarHBondContact O-N 2.82Å; E575-K578 PolarHBondContact O-N 2.77Å; E575-K578 VanDerWaalsContact O-N 3.15Å; E575-H579 PolarHBondContact O-CD2 3.5Å; E575-H579 PolarHBondContact O-N 3.47Å
576	R	87.6	Confident	85.4	Confident	82 Å²	82	88.7 Å²	88.7	31%	0.309	46%	0.457	S	S	.	.	H	α-helix	trans	-60.8	-40.5	179.1	-62.5	178.6	99.8	-173.2	9	111.7	I565 S566 S568 G570 T572 F573 A580	I565-R576 HydrophobicContact CG2-CB 4.27Å; I565-R576 PolarHBondContact O-NE 2.82Å; S566-R576 VanDerWaalsContact C-NH2 3.34Å; S566-R576 PolarHBondContact O-NH2 3.24Å; S568-R576 PolarHBondContact O-NE 3.31Å; S568-R576 PolarHBondContact O-NH2 2.98Å; G570-R576 WeakPolarHBondContact O-CD 3.13Å; G570-R576 WeakPolarHBondContact O-CG 3.12Å; T572-R576 WeakPolarHBondContact O-CG 3.3Å; T572-R576 PolarHBondContact O-N 2.87Å; T572-R576 VanDerWaalsContact O-N 3.07Å; F573-R576 PolarHBondContact O-N 3.05Å; R576-A580 VanDerWaalsContact O-CB 3.3Å; R576-A580 WeakPolarHBondContact O-CB 3.48Å; R576-A580 PolarHBondContact O-N 3.15Å
577	L	87.4	Confident	85.4	Confident	62 Å²	62	86.1 Å²	86.1	33%	0.325	44%	0.438	S	S	.	.	H	α-helix	trans	-64.4	-46.5	174.3	-177.9	62.5	0	0	0	111.5	M105 I565 F573 E575 H579 A580 C581	M105-L577 HydrophobicContact SD-CD1 3.64Å; I565-L577 HydrophobicContact CD1-CD1 3.9Å; I565-L577 HydrophobicContact CG1-CD1 4.36Å; F573-L577 HydrophobicContact CE1-CD2 4.33Å; F573-L577 WeakPolarHBondContact O-CB 3.41Å; F573-L577 PolarHBondContact O-N 3.31Å; E575-L577 VanDerWaalsContact C-N 3.3Å; E575-L577 PolarHBondContact O-N 2.82Å; L577-H579 VanDerWaalsContact C-N 3.34Å; L577-H579 PolarHBondContact O-N 2.99Å; L577-A580 PolarHBondContact O-N 3.32Å; L577-C581 PolarHBondContact O-N 2.96Å; L577-C581 PolarHBondContact O-SG 2.75Å; L577-C581 VanDerWaalsContact O-SG 3.41Å
578	K	86.9	Confident	85.4	Confident	141 Å²	141	77.7 Å²	77.7	61%	0.613	41%	0.407	S	S	*	.	H	α-helix	trans	-59.1	-45.3	177.1	-171.3	-178.8	179.5	-175.6	0	111.4	R574 E575 C581 Q582	R574-K578 WeakPolarHBondContact O-CB 3.35Å; R574-K578 PolarHBondContact O-N 2.99Å; E575-K578 PolarHBondContact O-N 2.77Å; E575-K578 VanDerWaalsContact O-N 3.15Å; K578-C581 PolarHBondContact O-N 3.47Å; K578-Q582 VanDerWaalsContact O-CG 3.31Å; K578-Q582 WeakPolarHBondContact O-CG 3.33Å; K578-Q582 PolarHBondContact O-N 3.11Å
579	H	85.6	Confident	85.5	Confident	86 Å²	86	77.5 Å²	77.5	40%	0.398	41%	0.405	S	S	.	.	H	α-helix	trans	-68.6	-32.8	177.3	-73.8	-57.9	0	0	0	113.3	P569 E575 L577 C581 Q582	P569-H579 PolarHBondContact O-CD2 2.92Å; E575-H579 PolarHBondContact O-CD2 3.5Å; E575-H579 PolarHBondContact O-N 3.47Å; L577-H579 VanDerWaalsContact C-N 3.34Å; L577-H579 PolarHBondContact O-N 2.99Å; H579-C581 VanDerWaalsContact C-N 3.34Å; H579-Q582 PolarHBondContact ND1-OE1 2.94Å; H579-Q582 VanDerWaalsContact ND1-OE1 3.12Å
580	A	86.1	Confident	85.6	Confident	0 Å²	0	74.7 Å²	74.7	0%	0	39%	0.39	C	S	.	.	H	α-helix	trans	-68.7	-33	175.7	0	0	0	0	0	112.7	P104 M105 K564 I565 R576 L577	P104-A580 WeakPolarHBondContact CD-O 3.28Å; M105-A580 HydrophobicContact CB-CB 4.14Å; M105-A580 WeakPolarHBondContact CB-O 3.4Å; M105-A580 PolarHBondContact N-O 2.95Å; K564-A580 HydrophobicContact CG-CB 4.32Å; I565-A580 HydrophobicContact CG1-CB 3.98Å; R576-A580 VanDerWaalsContact O-CB 3.3Å; R576-A580 WeakPolarHBondContact O-CB 3.48Å; R576-A580 PolarHBondContact O-N 3.15Å; L577-A580 PolarHBondContact O-N 3.32Å
581	C	86.9	Confident	85.7	Confident	27 Å²	27	74.9 Å²	74.9	18%	0.182	38%	0.383	C	S	.	.	H	α-helix	trans	-81.6	-22.9	178.7	-69.4	0	0	0	0	113.8	S103 M105 I483 L577 K578 H579	S103-C581 PolarHBondContact OG-O 2.91Å; M105-C581 WeakPolarHBondContact CE-SG 3.35Å; I483-C581 HydrophobicContact CG2-CB 3.9Å; L577-C581 PolarHBondContact O-N 2.96Å; L577-C581 PolarHBondContact O-SG 2.75Å; L577-C581 VanDerWaalsContact O-SG 3.41Å; K578-C581 PolarHBondContact O-N 3.47Å; H579-C581 VanDerWaalsContact C-N 3.34Å
582	Q	86.9	Confident	85.8	Confident	91 Å²	91	73.6 Å²	73.6	43%	0.425	37%	0.373	S	S	.	.	S	Bend	trans	-67.1	139.8	178.9	-81.2	171.6	-11.5	0	0	111.7	P104 K578 H579 H584	P104-Q582 WeakPolarHBondContact CD-O 3.19Å; K578-Q582 VanDerWaalsContact O-CG 3.31Å; K578-Q582 WeakPolarHBondContact O-CG 3.33Å; K578-Q582 PolarHBondContact O-N 3.11Å; H579-Q582 PolarHBondContact ND1-OE1 2.94Å; H579-Q582 VanDerWaalsContact ND1-OE1 3.12Å; Q582-H584 PolarHBondContact O-N 2.97Å
583	A	87.3	Confident	85.5	Confident	39 Å²	39	76.2 Å²	76.2	32%	0.322	38%	0.38	S	S	.	.	P	Polyproline II helix	trans	-56	136.3	175.1	0	0	0	0	0	110.9	I102 Y484 W587	I102-A583 WeakPolarHBondContact O-CA 3.43Å; I102-A583 VanDerWaalsContact O-CB 3.29Å; I102-A583 WeakPolarHBondContact O-CB 3.42Å; Y484-A583 HydrophobicContact CD2-CB 4.36Å; Y484-A583 HydrophobicContact CE2-CB 4.05Å; A583-W587 HydrophobicContact CB-CB 4.12Å; A583-W587 HydrophobicContact CB-CG 4.14Å
584	H	85.6	Confident	85.3	Confident	75 Å²	75	70.4 Å²	70.4	35%	0.347	36%	0.355	S	S	.	.	P	Polyproline II helix	trans	-60.9	146	177.2	-167.6	-84	0	0	0	109.7	K101 P104 Q582 K586 W587	K101-H584 HydrophobicContact CB-CB 4.2Å; K101-H584 WeakPolarHBondContact O-CB 3.4Å; K101-H584 PolarHBondContact O-N 3.5Å; P104-H584 HydrophobicContact CG-CB 4.18Å; Q582-H584 PolarHBondContact O-N 2.97Å; H584-K586 WeakPolarHBondContact ND1-CB 3.28Å; H584-K586 PolarHBondContact ND1-N 3.29Å; H584-K586 VanDerWaalsContact ND1-N 3.12Å; H584-K586 PolarHBondContact O-N 3.37Å; H584-W587 WeakPolarHBondContact O-CB 3.14Å; H584-W587 PolarHBondContact O-N 3.32Å
585	P	82.6	Confident	85.3	Confident	127 Å²	127	64 Å²	64	83%	0.825	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.8	-11.8	176.3	-27.5	34.7	0	0	0	115.8
586	K	83.7	Confident	85	Confident	141 Å²	141	63.5 Å²	63.5	61%	0.613	33%	0.334	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.5	4.1	177.4	-62.5	-175.9	177.7	-178.5	0	112.3	H584	H584-K586 WeakPolarHBondContact ND1-CB 3.28Å; H584-K586 PolarHBondContact ND1-N 3.29Å; H584-K586 VanDerWaalsContact ND1-N 3.12Å; H584-K586 PolarHBondContact O-N 3.37Å
587	W	88.5	Confident	84.8	Confident	11 Å²	11	62.8 Å²	62.8	4%	0.042	35%	0.351	C	S	.	.			trans	-71.5	143.1	171.5	174.9	-110.2	0	0	0	109.8	F88 F91 A92 V99 K101 I102 Y484 A583 H584 Y599	F88-W587 AromaticContact CD2-CH2 3.89Å; F88-W587 HydrophobicContact CD2-CH2 3.89Å; F88-W587 HydrophobicContact CD2-CZ2 4.49Å; F88-W587 AromaticContact CE2-CH2 3.44Å; F88-W587 HydrophobicContact CE2-CH2 3.44Å; F88-W587 VanDerWaalsContact CE2-CH2 3.44Å; F88-W587 HydrophobicContact CE2-CZ2 4.11Å; F88-W587 HydrophobicContact CE2-CZ3 4.18Å; F88-W587 HydrophobicContact CZ-CH2 4.48Å; F91-W587 HydrophobicContact CD1-CH2 4.18Å; F91-W587 AromaticContact CD1-CZ2 3.81Å; F91-W587 HydrophobicContact CD1-CZ2 3.81Å; F91-W587 AromaticContact CE1-CZ2 3.86Å; F91-W587 HydrophobicContact CE1-CZ2 3.86Å; A92-W587 HydrophobicContact CB-CH2 3.84Å; A92-W587 HydrophobicContact CB-CZ3 3.61Å; V99-W587 WeakPolarHBondContact O-CZ3 3.44Å; K101-W587 HydrophobicContact CB-CB 4.42Å; K101-W587 HydrophobicContact CB-CE3 3.98Å; I102-W587 HydrophobicContact CB-CD2 3.71Å; I102-W587 HydrophobicContact CB-CE3 3.86Å; I102-W587 HydrophobicContact CB-CG 4.42Å; I102-W587 HydrophobicContact CB-CH2 3.86Å; I102-W587 HydrophobicContact CB-CZ2 3.7Å; I102-W587 HydrophobicContact CB-CZ3 3.93Å; I102-W587 HydrophobicContact CD1-CH2 4.19Å; I102-W587 HydrophobicContact CD1-CZ2 3.55Å; I102-W587 HydrophobicContact CG1-CD2 4.1Å; I102-W587 HydrophobicContact CG1-CH2 4.31Å; I102-W587 HydrophobicContact CG1-CZ2 3.68Å; I102-W587 VanDerWaalsContact N-CE3 3.31Å; Y484-W587 AromaticContact CE2-NE1 3.75Å; Y484-W587 AromaticContact CZ-NE1 3.6Å; Y484-W587 PolarHBondContact OH-NE1 3.25Å; Y484-W587 VanDerWaalsContact OH-NE1 3.17Å; A583-W587 HydrophobicContact CB-CB 4.12Å; A583-W587 HydrophobicContact CB-CG 4.14Å; H584-W587 WeakPolarHBondContact O-CB 3.14Å; H584-W587 PolarHBondContact O-N 3.32Å; W587-Y599 AromaticContact CD1-CE1 4Å; W587-Y599 WeakPolarHBondContact O-CD1 3.44Å
588	G	87.4	Confident	84.5	Confident	3 Å²	3	66.4 Å²	66.4	3%	0.031	36%	0.361	C	S	.	.	S	Bend	trans	127.3	-173	-174.8	0	0	0	0	0	111.4
589	P	87.3	Confident	84.4	Confident	0 Å²	0	61 Å²	61	0%	0	34%	0.337	C	S	.	.			trans	-55.4	141.8	178.7	-26.2	36.4	0	0	0	112.2	F91 F318 M495 H594 R595	F91-P589 HydrophobicContact CE2-CG 4.08Å; F91-P589 HydrophobicContact CZ-CG 4.15Å; F318-P589 HydrophobicContact CD2-CB 4.15Å; F318-P589 HydrophobicContact CE2-CB 3.6Å; F318-P589 HydrophobicContact CE2-CG 3.56Å; F318-P589 HydrophobicContact CZ-CB 3.94Å; F318-P589 HydrophobicContact CZ-CG 3.53Å; M495-P589 HydrophobicContact SD-CG 4.39Å; P589-H594 HydrophobicContact CB-CB 3.58Å; P589-H594 HydrophobicContact CG-CB 4.21Å; P589-R595 HydrophobicContact CB-CG 4.33Å; P589-R595 PolarHBondContact O-NE 2.97Å; P589-R595 PolarHBondContact O-NH2 3Å
590	A	83.3	Confident	84	Confident	39 Å²	39	59.4 Å²	59.4	32%	0.322	34%	0.338	S	S	.	.	S	Bend	trans	-68	-40.9	-177.4	0	0	0	0	0	112.8	A92	A92-A590 WeakPolarHBondContact O-CB 3.46Å
591	L	82.2	Confident	83.3	Confident	38 Å²	38	64 Å²	64	20%	0.199	37%	0.368	C	S	.	.	S	Bend	trans	-87.7	141.1	-177.9	-59.6	167	0	0	0	110.5	E24 N25 E593 H594	E24-L591 HydrophobicContact CB-CD1 4.46Å; E24-L591 HydrophobicContact CG-CD1 3.6Å; N25-L591 HydrophobicContact CB-CD1 4.45Å; N25-L591 HydrophobicContact CB-CD2 4.36Å; L591-E593 VanDerWaalsContact C-N 3.27Å; L591-E593 HydrophobicContact CB-CG 3.9Å; L591-E593 WeakPolarHBondContact CD1-OE1 3.49Å; L591-E593 PolarHBondContact O-N 3.16Å; L591-H594 PolarHBondContact O-N 2.95Å
592	A	80.3	Confident	82	Confident	77 Å²	77	67.2 Å²	67.2	64%	0.636	40%	0.396	S	S	*	.	G	3₁₀ helix	trans	-64.4	-32.2	-178.2	0	0	0	0	0	112.6	H594 R595	A592-H594 PolarHBondContact O-N 3.35Å; A592-R595 WeakPolarHBondContact O-CB 3.36Å; A592-R595 PolarHBondContact O-N 3.25Å; A592-R595 VanDerWaalsContact O-N 3.15Å
593	E	81.8	Confident	80.2	Confident	124 Å²	124	66.9 Å²	66.9	58%	0.579	41%	0.41	S	S	*	.	G	3₁₀ helix	trans	-60.1	-31.5	176.4	62.7	-171.8	176.2	0	0	113.2	L591	L591-E593 VanDerWaalsContact C-N 3.27Å; L591-E593 HydrophobicContact CB-CG 3.9Å; L591-E593 WeakPolarHBondContact CD1-OE1 3.49Å; L591-E593 PolarHBondContact O-N 3.16Å
594	H	82.7	Confident	78	Confident	19 Å²	19	70.7 Å²	70.7	9%	0.088	43%	0.431	C	S	.	.	G	3₁₀ helix	trans	-89.3	-8.4	-179.7	-61.5	-41.5	0	0	0	113.2	E24 F318 P589 L591 A592 T596	E24-H594 IonicContact OE1-CD2 3.86Å; E24-H594 IonicContact OE1-CE1 2.62Å; E24-H594 PolarHBondContact OE1-CE1 3.16Å; E24-H594 VanDerWaalsContact OE1-CE1 3.28Å; E24-H594 IonicContact OE1-NE2 2.72Å; E24-H594 PolarHBondContact OE1-NE2 3.34Å; F318-H594 WeakPolarHBondContact CB-CD2 3.39Å; F318-H594 HydrophobicContact CD1-CB 3.61Å; F318-H594 AromaticContact CD1-CD2 3.73Å; F318-H594 AromaticContact CD1-CG 3.28Å; F318-H594 AromaticContact CD1-ND1 3.48Å; F318-H594 WeakPolarHBondContact CD1-ND1 3.34Å; F318-H594 HydrophobicContact CD2-CB 4.34Å; F318-H594 HydrophobicContact CE1-CB 3.68Å; F318-H594 AromaticContact CE1-CG 3.88Å; F318-H594 HydrophobicContact CE2-CB 4.41Å; F318-H594 HydrophobicContact CG-CB 3.96Å; F318-H594 AromaticContact CG-CD2 3.53Å; F318-H594 AromaticContact CG-CG 3.57Å; F318-H594 HydrophobicContact CZ-CB 4.1Å; P589-H594 HydrophobicContact CB-CB 3.58Å; P589-H594 HydrophobicContact CG-CB 4.21Å; L591-H594 PolarHBondContact O-N 2.95Å; A592-H594 PolarHBondContact O-N 3.35Å; H594-T596 VanDerWaalsContact C-N 3.34Å; H594-T596 PolarHBondContact O-N 3.18Å
595	R	84.3	Confident	75.5	Confident	77 Å²	77	71.5 Å²	71.5	29%	0.291	45%	0.45	S	S	.	.			trans	-80.2	83	178.4	-76.1	-172.4	-179.1	174.5	0.6	110.4	P589 A592 Y599 A600	P589-R595 HydrophobicContact CB-CG 4.33Å; P589-R595 PolarHBondContact O-NE 2.97Å; P589-R595 PolarHBondContact O-NH2 3Å; A592-R595 WeakPolarHBondContact O-CB 3.36Å; A592-R595 PolarHBondContact O-N 3.25Å; A592-R595 VanDerWaalsContact O-N 3.15Å; R595-Y599 WeakPolarHBondContact CB-O 3.3Å; R595-A600 WeakPolarHBondContact O-CA 3.43Å
596	T	81.4	Confident	73.2	Confident	75 Å²	75	73.6 Å²	73.6	46%	0.46	45%	0.449	S	S	.	.			trans	-111.9	163.2	178.5	60.6	0	0	0	0	111.7	H594 R598 Y599	H594-T596 VanDerWaalsContact C-N 3.34Å; H594-T596 PolarHBondContact O-N 3.18Å; T596-R598 PolarHBondContact O-N 3.16Å; T596-R598 VanDerWaalsContact O-N 3.11Å; T596-Y599 PolarHBondContact O-N 3.25Å; T596-Y599 VanDerWaalsContact O-N 3.08Å
597	G	82.7	Confident	70.7	Confident	66 Å²	66	72.7 Å²	72.7	68%	0.68	46%	0.456	S	S	*	.	G	3₁₀ helix	trans	55.7	-115.3	176.7	0	0	0	0	0	112.8	Y599 A600	G597-Y599 PolarHBondContact O-N 3.31Å; G597-A600 WeakPolarHBondContact O-CB 3.18Å; G597-A600 PolarHBondContact O-N 3.1Å
598	R	81.1	Confident	68.1	Low	139 Å²	139	79.1 Å²	79.1	53%	0.525	49%	0.49	S	S	.	.	G	3₁₀ helix	trans	-62.1	-24	-178.7	-177.4	-176.1	-72.5	175.5	-12.5	113.8	N488 T596	N488-R598 PolarHBondContact OD1-NH1 2.93Å; N488-R598 PolarHBondContact OD1-NH2 3.1Å; T596-R598 PolarHBondContact O-N 3.16Å; T596-R598 VanDerWaalsContact O-N 3.11Å
599	Y	84.3	Confident	65.4	Low	28 Å²	28	86.9 Å²	86.9	11%	0.11	53%	0.525	C	S	.	.	G	3₁₀ helix	trans	-101.8	-0.1	-177.8	-59.3	-71.1	0	0	0	113.6	F91 Y484 D492 M495 W587 R595 T596 G597	F91-Y599 HydrophobicContact CZ-CD2 4.36Å; F91-Y599 AromaticContact CZ-CE2 3.68Å; F91-Y599 HydrophobicContact CZ-CE2 3.68Å; F91-Y599 AromaticContact CZ-CZ 3.9Å; Y484-Y599 PolarHBondContact OH-OH 3.34Å; D492-Y599 WeakPolarHBondContact OD1-CE2 3.25Å; D492-Y599 PolarHBondContact OD1-OH 2.86Å; D492-Y599 PolarHBondContact OD2-OH 3.46Å; M495-Y599 HydrophobicContact CE-CD2 3.97Å; M495-Y599 HydrophobicContact CE-CE2 4.31Å; M495-Y599 HydrophobicContact SD-CD2 4.02Å; M495-Y599 HydrophobicContact SD-CE2 4.33Å; W587-Y599 AromaticContact CD1-CE1 4Å; W587-Y599 WeakPolarHBondContact O-CD1 3.44Å; R595-Y599 WeakPolarHBondContact CB-O 3.3Å; T596-Y599 PolarHBondContact O-N 3.25Å; T596-Y599 VanDerWaalsContact O-N 3.08Å; G597-Y599 PolarHBondContact O-N 3.31Å
600	A	77.5	Confident	62.7	Low	52 Å²	52	90.5 Å²	90.5	43%	0.43	56%	0.555	S	S	.	*	S	Bend	trans	-54.1	136.9	179.5	0	0	0	0	0	110.2	R595 G597 A602	R595-A600 WeakPolarHBondContact O-CA 3.43Å; G597-A600 WeakPolarHBondContact O-CB 3.18Å; G597-A600 PolarHBondContact O-N 3.1Å; A600-A602 PolarHBondContact O-N 2.75Å
601	P	70.8	Confident	60	Low	96 Å²	96	99.8 Å²	99.8	62%	0.623	58%	0.581	S	S	*	*	P	Polyproline II helix	trans	-54.5	131.4	171	-3	10.1	0	0	0	107.7	A603	P601-A603 PolarHBondContact O-N 3.24Å; P601-A603 VanDerWaalsContact O-N 3.14Å
602	A	60.8	Low	57.7	Low	94 Å²	94	103.3 Å²	103.3	78%	0.777	61%	0.607	S	S	*	*	P	Polyproline II helix	trans	-52.2	127.6	167.9	0	0	0	0	0	106.8	A600	A600-A602 PolarHBondContact O-N 2.75Å
603	A	48.6	Very low	55.7	Low	85 Å²	85	107 Å²	107	70%	0.702	62%	0.616	S	S	*	*	P	Polyproline II helix	trans	-48	133.1	175.1	0	0	0	0	0	107.4	P601 A605	P601-A603 PolarHBondContact O-N 3.24Å; P601-A603 VanDerWaalsContact O-N 3.14Å; A603-A605 PolarHBondContact O-N 2.65Å
604	P	40.9	Very low	53.3	Low	118 Å²	118	110.1 Å²	110.1	77%	0.766	63%	0.63	S	S	*	*	P	Polyproline II helix	trans	-52.5	123.8	170.7	20.8	-27.3	0	0	0	105.7	E606	P604-E606 PolarHBondContact O-N 3.48Å
605	A	33.6	Very low	50.8	Low	92 Å²	92	117.1 Å²	117.1	76%	0.76	67%	0.667	S	S	*	*			trans	-50.2	115.9	170.6	0	0	0	0	0	105.1	A603 T607	A603-A605 PolarHBondContact O-N 2.65Å; A605-T607 PolarHBondContact O-N 3.14Å
606	E	34	Very low	48.2	Very low	172 Å²	172	118.7 Å²	118.7	80%	0.804	69%	0.689	S	S	*	*			trans	-54	102.4	168.5	-75.6	177.5	163.3	0	0	104.9	P604 I608	P604-E606 PolarHBondContact O-N 3.48Å; E606-I608 HydrophobicContact CB-CG1 4.38Å; E606-I608 PolarHBondContact O-N 3.42Å
607	T	31.1	Very low	45.8	Very low	122 Å²	122	121.5 Å²	121.5	75%	0.748	70%	0.701	S	S	*	*			trans	-59.3	89.9	152	30.9	0	0	0	0	104.2	A605 E609	A605-T607 PolarHBondContact O-N 3.14Å; T607-E609 PolarHBondContact O-N 3.27Å
608	I	34.2	Very low	43.1	Very low	146 Å²	146	125.4 Å²	125.4	75%	0.749	71%	0.712	S	S	*	*			trans	-63.1	76.9	151.7	-56.9	175.9	0	0	0	104.1	E606 A610	E606-I608 HydrophobicContact CB-CG1 4.38Å; E606-I608 PolarHBondContact O-N 3.42Å; I608-A610 PolarHBondContact O-N 3.4Å
609	E	31.2	Very low	40.7	Very low	166 Å²	166	125.2 Å²	125.2	78%	0.776	72%	0.719	S	S	*	*			trans	-67	87.8	150.1	-80.3	-174.1	169.4	0	0	104.6	T607 R611	T607-E609 PolarHBondContact O-N 3.27Å; E609-R611 VanDerWaalsContact C-N 3.3Å; E609-R611 PolarHBondContact O-N 3.29Å
610	A	30.2	Very low	38	Very low	75 Å²	75	133.1 Å²	133.1	62%	0.62	76%	0.758	S	S	*	*			trans	-54.1	105.4	155.6	0	0	0	0	0	105.6	I608 P612	I608-A610 PolarHBondContact O-N 3.4Å; A610-P612 WeakPolarHBondContact O-CD 3.37Å
611	R	27.3	Very low	35.6	Very low	235 Å²	235	134.2 Å²	134.2	89%	0.887	77%	0.774	S	S	*	*			trans	-62.6	111	162	-77.1	-174.8	-173.3	-178.2	2	106.2	E609 D613	E609-R611 VanDerWaalsContact C-N 3.3Å; E609-R611 PolarHBondContact O-N 3.29Å; R611-D613 PolarHBondContact O-N 3.37Å
612	P	34.1	Very low	33.6	Very low	112 Å²	112	135.1 Å²	135.1	73%	0.727	78%	0.782	S	S	*	*			trans	-92.4	85	169.7	28.8	-10.9	0	0	0	105.4	A610	A610-P612 WeakPolarHBondContact O-CD 3.37Å
613	D	36.2	Very low	32.1	Very low	154 Å²	154	138.5 Å²	138.5	82%	0.824	79%	0.787	S	S	*	*			trans	-173	81.7	163.8	-85.6	-29.5	0	0	0	109.2	R611	R611-D613 PolarHBondContact O-N 3.37Å
614	E	33	Very low	31.1	Very low	189 Å²	189	137.8 Å²	137.8	88%	0.883	79%	0.788	S	S	*	*			trans	-176.8	72.5	140	-103.2	178.2	-175.7	0	0	108.1
615	I	30.5	Very low	30.4	Very low	167 Å²	167	137.4 Å²	137.4	86%	0.856	79%	0.788	S	S	*	*			trans	-109.9	98.4	156.4	-60	175.6	0	0	0	105.9
616	S	29.5	Very low	30.2	Very low	109 Å²	109	138.6 Å²	138.6	76%	0.762	79%	0.786	S	S	*	*			trans	-126.1	114.9	157.7	48.1	0	0	0	0	108.6
617	L	30.1	Very low	29.9	Very low	135 Å²	135	137.8 Å²	137.8	71%	0.707	79%	0.787	S	S	*	*			trans	-51.8	143.9	178.7	-75.4	108.2	0	0	0	113.6	I619	L617-I619 HydrophobicContact CD2-CD1 3.97Å; L617-I619 HydrophobicContact CD2-CG1 4.31Å
618	T	26.6	Very low	29.8	Very low	148 Å²	148	137.2 Å²	137.2	91%	0.908	78%	0.784	S	S	*	*			trans	-147.2	123.1	130.3	-23.5	0	0	0	0	110.8
619	I	30.3	Very low	29.6	Very low	134 Å²	134	138 Å²	138	69%	0.687	78%	0.784	S	S	*	*			trans	-86.8	146.7	175.6	-67.8	160.1	0	0	0	108.8	L617	L617-I619 HydrophobicContact CD2-CD1 3.97Å; L617-I619 HydrophobicContact CD2-CG1 4.31Å
620	Q	27.9	Very low	29.6	Very low	195 Å²	195	136.8 Å²	136.8	91%	0.911	78%	0.783	S	S	*	*			trans	138.6	134.3	152	-81.1	177.1	0	0	0	108.6
621	G	27.7	Very low	29.5	Very low	75 Å²	75	140.6 Å²	140.6	77%	0.773	79%	0.793	S	S	*	*			cis	165.3	144.2	9.5	0	0	0	0	0	106
622	S	28.9	Very low	30.7	Very low	115 Å²	115	133.9 Å²	133.9	80%	0.804	78%	0.78	S	S	*	*			trans	-52.3	137.4	175.5	173.7	0	0	0	0	113
623	N	28.6	Very low	30.5	Very low	164 Å²	164	135.7 Å²	135.7	88%	0.877	78%	0.783	S	S	*	*			trans	-169.2	129.5	137	-97.6	-14.1	0	0	0	110.7
624	G	26.6	Very low	31.2	Very low	70 Å²	70	132.9 Å²	132.9	72%	0.722	77%	0.774	S	S	*	*			trans	-93	158.7	172	0	0	0	0	0	112.8
625	S	27.7	Very low	31.3	Very low	110 Å²	110	129.2 Å²	129.2	77%	0.769	77%	0.769	S	S	*	*			trans	173.6	121.8	140	57.8	0	0	0	0	110.8
626	T	28	Very low	31.8	Very low	117 Å²	117	129.8 Å²	129.8	72%	0.718	80%	0.799	S	S	*	*			trans	32.4	121.7	138.4	54.2	0	0	0	0	120.3
627	N	28.7	Very low	31.9	Very low	155 Å²	155	130.9 Å²	130.9	83%	0.829	80%	0.801	S	S	*	*				-177	148.4	104.1	-95.4	-23	0	0	0	114.3
628	T	28.5	Very low	32	Very low	111 Å²	111	130.6 Å²	130.6	68%	0.681	81%	0.806	S	S	*	*			trans	-56.6	146	174.8	45.5	0	0	0	0	115.6
629	H	31.4	Very low	32.3	Very low	162 Å²	162	129.7 Å²	129.7	75%	0.75	80%	0.8	S	S	*	*				-177.6	124.4	121.8	-100.9	-64	0	0	0	113.9
630	N	30	Very low	32.4	Very low	141 Å²	141	129.4 Å²	129.4	75%	0.754	81%	0.807	S	S	*	*			trans	43.3	113.9	137.6	-65.5	-11.4	0	0	0	122.6
631	N	29.2	Very low	32.7	Very low	154 Å²	154	125.3 Å²	125.3	82%	0.824	80%	0.8	S	S	*	*				-14.2	169.7	128.4	-116.4	-0.5	0	0	0	117.7
632	P	50.8	Low	33	Very low	95 Å²	95	128.7 Å²	128.7	62%	0.617	80%	0.802	S	S	*	*			cis	-141	-171.7	-6.3	32.4	-9.4	0	0	0	114.9
633	N	30.9	Very low	33.3	Very low	149 Å²	149	129.6 Å²	129.6	80%	0.797	80%	0.802	S	S	*	*			trans	111.3	149.1	139	-93.6	10.6	0	0	0	120
634	P	50.3	Low	33.7	Very low	95 Å²	95	127 Å²	127	62%	0.617	80%	0.796	S	S	*	*				-133.3	-179.5	-117.1	34.2	-11.7	0	0	0	114.6
635	S	36.4	Very low	34.2	Very low	113 Å²	113	131.8 Å²	131.8	79%	0.79	80%	0.802	S	S	*	*			trans	55.8	112.1	147.8	59.1	0	0	0	0	119.8
636	A	39.1	Very low	34.8	Very low	179 Å²	179	133.7 Å²	133.7	100%	1.479	81%	0.805	S	S	*	*				-155.5	0	117.5	0	0	0	0	0	109.2

Retrieved 636 of 636 residues in 140.2 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).