A0A087YP96_POEFO Loading...

5'-nucleotidase, cytosolic II, like 1

AlphaFold DB , UniProt , Accession A0A087YP96, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 498 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M42.2Very low33.8Very low239 Ų239140.1 Ų140.1100%1.17777%0.77SS**  093.20-87.3178.6174.700106.3K3M1-K3 PolarHBondContact O-N 3.48Å
2D29.2Very low33.5Very low162 Ų162140.8 Ų140.887%0.86676%0.764SS**  trans-66.6127.8-172.1-65.1-45.9000110.6L4D2-L4 PolarHBondContact O-N 3.37Å
3K37.2Very low34Very low204 Ų204137.3 Ų137.389%0.88774%0.741SS**  trans-65.8110.2167.8-74.7-179.4174.6-179.10107.4M1M1-K3 PolarHBondContact O-N 3.48Å
4L34.9Very low34.2Very low164 Ų164133.1 Ų133.186%0.85974%0.735SS**  trans-55.7129.8166.2-85.7149.1000109D2 C6D2-L4 PolarHBondContact O-N 3.37Å; L4-C6 PolarHBondContact O-N 3.31Å
5P35.5Very low34.5Very low118 Ų118134.6 Ų134.677%0.76674%0.741SS**  trans-73.8110.6177.128.9-31.2000108.9G7P5-G7 PolarHBondContact O-N 2.96Å
6C34.2Very low35.7Very low129 Ų129131.5 Ų131.587%0.87272%0.715SS**  trans-66.582.3159.3-85.80000108.2L4L4-C6 PolarHBondContact O-N 3.31Å
7G32Very low38Very low33 Ų33128.5 Ų128.534%0.3470%0.698SS.*  trans-75174.2172.200000112.9P5 L9P5-G7 PolarHBondContact O-N 2.96Å; G7-L9 PolarHBondContact O-N 3.36Å
8P31.1Very low40.2Very low98 Ų98127.1 Ų127.164%0.63669%0.685SS**THydrogen-bonded Turntrans-66.915.6-167.929.2-37.7000116.1Q12P8-Q12 PolarHBondContact O-N 3.02Å
9L32.6Very low42.3Very low130 Ų130125.7 Ų125.768%0.68167%0.673SS**Hα-helixtrans-73.9-25.5177.4-79.8158.7000112.8G7G7-L9 PolarHBondContact O-N 3.36Å
10V34.3Very low44.7Very low111 Ų111124.3 Ų124.367%0.67366%0.661SS**Hα-helixtrans-71.5-34.2176.1-176.80000111
11E28.2Very low47Very low153 Ų153121.1 Ų121.172%0.71564%0.641SS**Hα-helixtrans-74.4-30.5176.4-78.4-179.9153.400113M13 A14E11-M13 VanDerWaalsContact C-N 3.27Å; E11-M13 PolarHBondContact O-N 2.74Å; E11-A14 WeakPolarHBondContact O-CB 3.1Å; E11-A14 PolarHBondContact O-N 3.43Å
12Q30.4Very low49.7Very low148 Ų148110.1 Ų110.169%0.69259%0.587SS**Hα-helixtrans-69.9-20.2175.8-77.6-172-10.800113.9P8P8-Q12 PolarHBondContact O-N 3.02Å
13M40.2Very low52.9Low96 Ų96104.3 Ų104.347%0.47355%0.554SS.*Hα-helixtrans-84.5-18.1173.5-69.3-17566.300113.4E11 N15 Y460E11-M13 VanDerWaalsContact C-N 3.27Å; E11-M13 PolarHBondContact O-N 2.74Å; M13-N15 PolarHBondContact O-N 3.34Å; M13-Y460 VanDerWaalsContact CE-OH 3.29Å; M13-Y460 WeakPolarHBondContact CE-OH 3.37Å
14A36.8Very low55.8Low79 Ų7996.4 Ų96.465%0.65352%0.523SS*.Hα-helixtrans-73.4-16.8-179.800000113E11E11-A14 WeakPolarHBondContact O-CB 3.1Å; E11-A14 PolarHBondContact O-N 3.43Å
15N39.1Very low58.8Low155 Ų15590.3 Ų90.383%0.82949%0.492SS*.THydrogen-bonded Turntrans-107.120-174.9-1291.1000114M13 D17M13-N15 PolarHBondContact O-N 3.34Å; N15-D17 PolarHBondContact O-N 3.34Å
16R53.7Low61.7Low85 Ų8588.1 Ų88.132%0.32147%0.468SS..SBendtrans-80.9113.8166.9-71.9-173.3-178-160.9-4108.3F18 H455R16-F18 PolarHBondContact O-N 3.41Å; R16-H455 PolarHBondContact NH1-O 3.3Å; R16-H455 PolarHBondContact NH2-O 3.01Å
17D75.1Confident64.7Low80 Ų8084.9 Ų84.943%0.42845%0.447SS..  trans-37.1124.5165.3-163.5-14.8000110.1N15 E19 K20N15-D17 PolarHBondContact O-N 3.34Å; D17-E19 PolarHBondContact O-N 3.4Å; D17-K20 HydrophobicContact CB-CD 4.39Å; D17-K20 PolarHBondContact O-N 2.92Å
18F77.2Confident67.8Low104 Ų10483.5 Ų83.546%0.45643%0.432SS..G310 helixtrans-56.5-26.7-175-73.2-77.4000111.7R16 K20 K21 L364R16-F18 PolarHBondContact O-N 3.41Å; F18-K20 PolarHBondContact O-N 3.25Å; F18-K21 HydrophobicContact CD1-CD 4.41Å; F18-K21 PolarHBondContact O-N 3.28Å; F18-L364 HydrophobicContact CB-CD1 4.28Å
19E80.3Confident71Confident100 Ų10080.9 Ų80.947%0.46741%0.414SS..G310 helixtrans-60.2-23.7174.8-61.4-171.6170.400113.8D17 N452D17-E19 PolarHBondContact O-N 3.4Å; E19-N452 PolarHBondContact O-ND2 2.93Å; E19-N452 PolarHBondContact O-OD1 2.72Å
20K89.4Confident74Confident97 Ų9774.9 Ų74.942%0.42238%0.382SS..G310 helixtrans-103.84.1-175.7-65.1176.2-173161.90113.7D17 F18 N452D17-K20 HydrophobicContact CB-CD 4.39Å; D17-K20 PolarHBondContact O-N 2.92Å; F18-K20 PolarHBondContact O-N 3.25Å; K20-N452 WeakPolarHBondContact CA-OD1 3.27Å
21K94.2Very high76.9Confident59 Ų5975.3 Ų75.326%0.25738%0.377SS..PPolyproline II helixtrans-87.7138.7-174.4-113173.9-179.6167.20112F18 F23 S447F18-K21 HydrophobicContact CD1-CD 4.41Å; F18-K21 PolarHBondContact O-N 3.28Å; K21-F23 HydrophobicContact CB-CE1 4.46Å; K21-F23 HydrophobicContact CB-CE2 4.28Å; K21-F23 HydrophobicContact CB-CZ 4.12Å; K21-F23 HydrophobicContact CD-CE1 4.48Å; K21-S447 PolarHBondContact O-OG 3.33Å
22V97.8Very high80.2Confident7 Ų772.6 Ų72.64%0.04237%0.368CS..PPolyproline II helixtrans-94.4121.8159.8176.70000107.6F354 L445 N452 L453 Y456 F462V22-F354 HydrophobicContact CB-CE2 4.44Å; V22-F354 HydrophobicContact CG1-CD2 4.42Å; V22-F354 HydrophobicContact CG1-CE2 3.67Å; V22-F354 HydrophobicContact CG1-CZ 4.35Å; V22-F354 HydrophobicContact CG2-CE2 3.89Å; V22-F354 HydrophobicContact CG2-CZ 4.16Å; V22-L445 HydrophobicContact CG1-CB 4Å; V22-L445 HydrophobicContact CG1-CD1 4.24Å; V22-L445 HydrophobicContact CG1-CD2 4.23Å; V22-L445 HydrophobicContact CG1-CG 4.39Å; V22-N452 HydrophobicContact CG2-CB 3.86Å; V22-L453 HydrophobicContact CG2-CD2 4.3Å; V22-Y456 HydrophobicContact CB-CE2 3.94Å; V22-Y456 HydrophobicContact CG2-CD2 4.17Å; V22-Y456 HydrophobicContact CG2-CE2 3.71Å; V22-Y456 PolarHBondContact N-OH 3.48Å; V22-Y456 VanDerWaalsContact N-OH 3.11Å; V22-F462 HydrophobicContact CB-CE1 3.72Å; V22-F462 HydrophobicContact CB-CZ 3.96Å; V22-F462 HydrophobicContact CG1-CD1 4.38Å; V22-F462 HydrophobicContact CG1-CE1 3.75Å; V22-F462 HydrophobicContact CG1-CZ 3.86Å; V22-F462 HydrophobicContact CG2-CZ 4.41Å
23F97.7Very high83.4Confident40 Ų4065.9 Ų65.918%0.17534%0.336CS..EExtended strand (participates in β ladder)trans-90.4150.5178.5-60.2-85000110.5K21 L360 L364 L445 Y446K21-F23 HydrophobicContact CB-CE1 4.46Å; K21-F23 HydrophobicContact CB-CE2 4.28Å; K21-F23 HydrophobicContact CB-CZ 4.12Å; K21-F23 HydrophobicContact CD-CE1 4.48Å; F23-L360 HydrophobicContact CD2-CD2 3.89Å; F23-L360 HydrophobicContact CE2-CD2 3.71Å; F23-L364 HydrophobicContact CE2-CD1 3.97Å; F23-L364 HydrophobicContact CZ-CD1 3.81Å; F23-L364 HydrophobicContact CZ-CD2 4.23Å; F23-L445 WeakPolarHBondContact O-CA 3.27Å; F23-Y446 HydrophobicContact CB-CD1 3.71Å; F23-Y446 HydrophobicContact CB-CD2 4.1Å; F23-Y446 HydrophobicContact CB-CE1 3.25Å; F23-Y446 HydrophobicContact CB-CE2 3.67Å; F23-Y446 HydrophobicContact CB-CG 4.11Å; F23-Y446 HydrophobicContact CD2-CD2 4.19Å; F23-Y446 AromaticContact CD2-CE2 3.77Å; F23-Y446 HydrophobicContact CD2-CE2 3.77Å; F23-Y446 HydrophobicContact CG-CD2 4.48Å; F23-Y446 HydrophobicContact CG-CE1 4.24Å; F23-Y446 AromaticContact CG-CE2 3.84Å; F23-Y446 HydrophobicContact CG-CE2 3.84Å; F23-Y446 AromaticContact CG-CZ 3.69Å; F23-Y446 PolarHBondContact N-O 3.34Å; F23-Y446 PolarHBondContact O-N 3.04Å
24V98.1Very high86.2Confident38 Ų3866.3 Ų66.323%0.2334%0.336CS..EExtended strand (participates in β ladder)trans-128119-165.8-169.30000110.1R26 L445 F462 A464V24-R26 WeakPolarHBondContact CG1-O 3.25Å; V24-L445 HydrophobicContact CB-CD2 4.22Å; V24-L445 HydrophobicContact CG1-CD2 3.93Å; V24-L445 HydrophobicContact CG2-CD2 3.94Å; V24-F462 HydrophobicContact CB-CB 4.48Å; V24-F462 HydrophobicContact CG1-CB 3.87Å; V24-F462 HydrophobicContact CG2-CB 3.72Å; V24-F462 HydrophobicContact CG2-CD1 3.51Å; V24-F462 HydrophobicContact CG2-CG 3.98Å; V24-A464 HydrophobicContact CG1-CB 4.11Å
25N97.6Very high89.1Confident37 Ų3762.6 Ų62.620%0.19830%0.304CS..SBendtrans-97.4-31170.3-64-49.3000111.9L439 A443 D444 Y446 A464N25-L439 PolarHBondContact ND2-O 3.18Å; N25-A443 WeakPolarHBondContact CB-O 3.42Å; N25-A443 PolarHBondContact ND2-O 3.33Å; N25-D444 PolarHBondContact N-O 3.46Å; N25-Y446 WeakPolarHBondContact ND2-CD1 2.92Å; N25-A464 WeakPolarHBondContact O-CB 3.1Å
26R96.6Very high91.9Very high72 Ų7255.3 Ų55.327%0.27227%0.265SS..SBendtrans-138.1137.4178.4-79.8165.9-76.2-77.3-9.6109.7V24 L28 I440 R441 Y442 A443 D444V24-R26 WeakPolarHBondContact CG1-O 3.25Å; R26-L28 PolarHBondContact O-N 3.1Å; R26-I440 VanDerWaalsContact CZ-O 3.26Å; R26-I440 PolarHBondContact NH1-O 2.88Å; R26-I440 PolarHBondContact NH2-O 2.81Å; R26-R441 VanDerWaalsContact CZ-O 3.24Å; R26-R441 PolarHBondContact NH1-O 3.21Å; R26-R441 VanDerWaalsContact NH1-O 3.08Å; R26-R441 PolarHBondContact NH2-O 3Å; R26-Y442 VanDerWaalsContact NH2-C 3.3Å; R26-A443 PolarHBondContact NH2-O 2.82Å; R26-D444 HydrophobicContact CB-CB 4.33Å; R26-D444 VanDerWaalsContact CD-OD1 3.26Å; R26-D444 WeakPolarHBondContact CD-OD1 3.35Å; R26-D444 IonicContact CZ-OD1 2.69Å; R26-D444 PolarHBondContact N-O 2.85Å; R26-D444 IonicContact NE-OD1 2.75Å; R26-D444 PolarHBondContact NE-OD1 3.24Å
27S97Very high94.1Very high61 Ų6151.2 Ų51.243%0.42725%0.25SS..  trans-59.1137.7-179-54.60000111.8F462 A464S27-F462 CarbonylContact C-O 3.58Å; S27-F462 WeakPolarHBondContact CA-O 3.37Å; S27-F462 WeakPolarHBondContact CB-O 3.31Å; S27-A464 PolarHBondContact OG-N 2.87Å
28L97.1Very high95.2Very high4 Ų447.4 Ų47.42%0.02123%0.23CC..EExtended strand (participates in β ladder)trans-148.2124.3-175.8-173.4155.2000109.7R26 L30 I33 L332 K352 D444 L445 F462R26-L28 PolarHBondContact O-N 3.1Å; L28-L30 HydrophobicContact CD2-CD2 3.69Å; L28-L30 HydrophobicContact CD2-CG 4.3Å; L28-I33 HydrophobicContact CD2-CD1 4.29Å; L28-I33 HydrophobicContact CD2-CG1 4.1Å; L28-L332 HydrophobicContact CD1-CD1 4.04Å; L28-K352 HydrophobicContact CD1-CB 3.76Å; L28-K352 HydrophobicContact CD1-CD 4.06Å; L28-K352 HydrophobicContact CD1-CG 4Å; L28-D444 HydrophobicContact CD1-CB 4.34Å; L28-L445 HydrophobicContact CD1-CD1 4.1Å; L28-L445 HydrophobicContact CD1-CG 4.3Å; L28-L445 HydrophobicContact CD2-CD1 4.28Å; L28-F462 HydrophobicContact CB-CB 4.47Å; L28-F462 HydrophobicContact CD2-CD2 4.41Å; L28-F462 PolarHBondContact N-O 2.98Å; L28-F462 WeakPolarHBondContact O-CB 3.39Å; L28-F462 PolarHBondContact O-N 3.21Å
29T96.8Very high96.2Very high42 Ų4243 Ų4326%0.25821%0.211SC..EExtended strand (participates in β ladder)trans-94.8117.6173.3-42.20000109.4E31 N32 L461T29-E31 HydrophobicContact CG2-CB 4.1Å; T29-E31 PolarHBondContact O-N 2.62Å; T29-N32 PolarHBondContact O-N 3.06Å; T29-L461 HydrophobicContact CG2-CD1 4.46Å; T29-L461 VanDerWaalsContact OG1-CD1 3.25Å; T29-L461 WeakPolarHBondContact OG1-CD1 3.48Å
30L97Very high97Very high4 Ų438.2 Ų38.22%0.02119%0.188CC..G310 helixtrans-64.5-28.4-178.4-73.2-177.6000113L28 N32 I33 L332 F458 Y460 F462L28-L30 HydrophobicContact CD2-CD2 3.69Å; L28-L30 HydrophobicContact CD2-CG 4.3Å; L30-N32 PolarHBondContact O-N 3.39Å; L30-I33 WeakPolarHBondContact O-CB 3.33Å; L30-I33 PolarHBondContact O-N 3.02Å; L30-L332 HydrophobicContact CD2-CD2 4.33Å; L30-F458 CarbonylContact C-O 3.32Å; L30-F458 WeakPolarHBondContact CB-O 3.31Å; L30-Y460 PolarHBondContact N-O 2.92Å; L30-F462 HydrophobicContact CD1-CE2 3.81Å; L30-F462 HydrophobicContact CD2-CD2 4.49Å; L30-F462 HydrophobicContact CD2-CE2 4.04Å; L30-F462 HydrophobicContact CG-CD2 4.23Å; L30-F462 HydrophobicContact CG-CE2 3.82Å
31E95.6Very high97.4Very high121 Ų12134.2 Ų34.257%0.56517%0.172SC*.G310 helixtrans-61.1-27.5178.7-170.7173-170.300113T29 I33 K34 F458T29-E31 HydrophobicContact CG2-CB 4.1Å; T29-E31 PolarHBondContact O-N 2.62Å; E31-I33 VanDerWaalsContact C-N 3.32Å; E31-K34 PolarHBondContact O-NZ 3.21Å; E31-F458 WeakPolarHBondContact CA-O 3.5Å; E31-F458 PolarHBondContact N-O 3.32Å
32N96.4Very high97.6Very high96 Ų9631.7 Ų31.751%0.51316%0.161SC..G310 helixtrans-81-15.3179-65.5-13.4000112.4T29 L30 K34T29-N32 PolarHBondContact O-N 3.06Å; L30-N32 PolarHBondContact O-N 3.39Å; N32-K34 PolarHBondContact O-N 2.83Å
33I98.1Very high97.6Very high7 Ų731.5 Ų31.54%0.03616%0.159CC..  trans-79.4119.5179.2-54.5-55.8000108.8L28 L30 E31 C35 Y36 D330 L332 K352L28-I33 HydrophobicContact CD2-CD1 4.29Å; L28-I33 HydrophobicContact CD2-CG1 4.1Å; L30-I33 WeakPolarHBondContact O-CB 3.33Å; L30-I33 PolarHBondContact O-N 3.02Å; E31-I33 VanDerWaalsContact C-N 3.32Å; I33-C35 VanDerWaalsContact CG2-O 3.29Å; I33-C35 WeakPolarHBondContact CG2-O 3.41Å; I33-Y36 HydrophobicContact CB-CE2 4.03Å; I33-Y36 HydrophobicContact CG2-CD2 3.83Å; I33-Y36 HydrophobicContact CG2-CE1 4.2Å; I33-Y36 HydrophobicContact CG2-CE2 3.44Å; I33-Y36 VanDerWaalsContact CG2-CE2 3.44Å; I33-Y36 HydrophobicContact CG2-CG 4.35Å; I33-D330 CarbonylContact C-O 3.51Å; I33-L332 HydrophobicContact CD1-CB 4.21Å; I33-L332 HydrophobicContact CG1-CB 4.28Å; I33-L332 HydrophobicContact CG2-CB 3.67Å; I33-K352 HydrophobicContact CD1-CB 4.25Å; I33-K352 HydrophobicContact CD1-CG 3.99Å
34K98.1Very high97.6Very high105 Ų10529.9 Ų29.946%0.45715%0.153SC..  trans-102.2-14.7178.7-50.7-53.1177.3-166.50112.6E31 N32 A230 K231 V326 D330E31-K34 PolarHBondContact O-NZ 3.21Å; N32-K34 PolarHBondContact O-N 2.83Å; K34-A230 WeakPolarHBondContact O-CB 3.12Å; K34-K231 PolarHBondContact O-N 2.88Å; K34-V326 HydrophobicContact CB-CG1 4.39Å; K34-D330 HydrophobicContact CB-CB 4.14Å; K34-D330 HydrophobicContact CG-CB 4.18Å; K34-D330 PolarHBondContact N-O 2.86Å
35C98.4Very high97.6Very high0 Ų028 Ų280%014%0.142CC..EExtended strand (participates in β ladder)trans-143.7135.8178.9-161.70000112.8I33 K231 F233 V326 D330 I331 L332I33-C35 VanDerWaalsContact CG2-O 3.29Å; I33-C35 WeakPolarHBondContact CG2-O 3.41Å; C35-K231 CarbonylContact C-O 3.48Å; C35-K231 VanDerWaalsContact CA-O 3.27Å; C35-K231 WeakPolarHBondContact CA-O 3.37Å; C35-K231 HydrophobicContact CB-CB 4.47Å; C35-F233 WeakPolarHBondContact SG-CD1 3.47Å; C35-V326 HydrophobicContact CB-CB 4.33Å; C35-V326 HydrophobicContact CB-CG1 4.08Å; C35-V326 HydrophobicContact CB-CG2 4.03Å; C35-D330 PolarHBondContact N-O 3.14Å; C35-I331 HydrophobicContact CB-CG1 4.12Å; C35-I331 WeakPolarHBondContact O-CA 3.27Å; C35-L332 PolarHBondContact O-N 3.36Å
36Y98.6Very high97.6Very high2 Ų228 Ų281%0.00814%0.14CC..EExtended strand (participates in β ladder)trans-113.3116.5175.5-68.7-107.9000109I33 I226 A230 K231 I232 F233 L332 I334I33-Y36 HydrophobicContact CB-CE2 4.03Å; I33-Y36 HydrophobicContact CG2-CD2 3.83Å; I33-Y36 HydrophobicContact CG2-CE1 4.2Å; I33-Y36 HydrophobicContact CG2-CE2 3.44Å; I33-Y36 VanDerWaalsContact CG2-CE2 3.44Å; I33-Y36 HydrophobicContact CG2-CG 4.35Å; Y36-I226 HydrophobicContact CD1-CD1 4.02Å; Y36-I226 HydrophobicContact CD1-CG2 4.31Å; Y36-I226 HydrophobicContact CD2-CG2 3.33Å; Y36-I226 HydrophobicContact CE1-CD1 4.48Å; Y36-I226 HydrophobicContact CE2-CG2 3.89Å; Y36-I226 HydrophobicContact CG-CD1 4.23Å; Y36-I226 HydrophobicContact CG-CG2 3.59Å; Y36-A230 HydrophobicContact CD2-CB 3.68Å; Y36-A230 HydrophobicContact CE2-CB 3.66Å; Y36-K231 PolarHBondContact N-O 2.74Å; Y36-I232 CarbonylContact O-C 3.56Å; Y36-I232 VanDerWaalsContact O-CA 3.3Å; Y36-I232 WeakPolarHBondContact O-CA 3.33Å; Y36-F233 PolarHBondContact O-N 2.71Å; Y36-L332 WeakPolarHBondContact CA-O 3.2Å; Y36-L332 HydrophobicContact CD1-CB 4.34Å; Y36-L332 HydrophobicContact CD1-CD2 4.06Å; Y36-L332 HydrophobicContact CE1-CB 4.49Å; Y36-L332 HydrophobicContact CE1-CD2 3.77Å; Y36-I334 HydrophobicContact CD1-CD1 4.1Å
37G98.3Very high97.6Very high0 Ų024.9 Ų24.90%013%0.129CC..EExtended strand (participates in β ladder)trans-105135.4177.100000111.2F233 L332 Y333 I334G37-F233 CarbonylContact C-O 3.47Å; G37-F233 WeakPolarHBondContact CA-O 3.46Å; G37-L332 PolarHBondContact N-O 2.84Å; G37-Y333 CarbonylContact O-C 3.51Å; G37-Y333 WeakPolarHBondContact O-CA 3.29Å; G37-Y333 WeakPolarHBondContact O-CD2 3.41Å; G37-I334 WeakPolarHBondContact O-CD1 3.48Å; G37-I334 PolarHBondContact O-N 3.35Å
38F98.7Very high97.7Very high0 Ų025.7 Ų25.70%013%0.125CC..EExtended strand (participates in β ladder)trans-118.7141.4-179.7-68.4-94.9000111.1L44 L223 I226 I232 F233 L234 A235 I334 C450F38-L44 HydrophobicContact CB-CD1 3.72Å; F38-L44 HydrophobicContact CB-CG 4.11Å; F38-L44 HydrophobicContact CD1-CD1 4.29Å; F38-L44 HydrophobicContact CD1-CD2 3.67Å; F38-L44 HydrophobicContact CD1-CG 3.95Å; F38-L44 HydrophobicContact CE1-CD2 4.04Å; F38-L44 HydrophobicContact CG-CD1 4.12Å; F38-L44 HydrophobicContact CG-CD2 4.27Å; F38-L44 HydrophobicContact CG-CG 4.28Å; F38-L223 HydrophobicContact CD2-CD2 4.25Å; F38-L223 HydrophobicContact CE2-CD2 3.75Å; F38-L223 HydrophobicContact CZ-CD2 3.91Å; F38-I226 HydrophobicContact CE2-CD1 4.27Å; F38-I226 HydrophobicContact CZ-CD1 3.89Å; F38-I232 HydrophobicContact CD2-CG2 3.92Å; F38-I232 HydrophobicContact CE2-CG2 3.93Å; F38-F233 PolarHBondContact N-O 2.83Å; F38-L234 HydrophobicContact CB-CD1 4.28Å; F38-A235 PolarHBondContact O-N 3.33Å; F38-I334 HydrophobicContact CD1-CB 4Å; F38-I334 HydrophobicContact CD1-CD1 4.12Å; F38-I334 HydrophobicContact CD1-CG2 4.22Å; F38-I334 HydrophobicContact CD2-CD1 4.43Å; F38-I334 HydrophobicContact CE1-CB 4.22Å; F38-I334 HydrophobicContact CE1-CD1 3.77Å; F38-I334 HydrophobicContact CE1-CG1 4.35Å; F38-I334 HydrophobicContact CE1-CG2 4.31Å; F38-I334 HydrophobicContact CE2-CD1 4.09Å; F38-I334 HydrophobicContact CG-CD1 4.45Å; F38-I334 HydrophobicContact CZ-CD1 3.76Å; F38-C450 HydrophobicContact CE1-CB 4.35Å
39D98.4Very high97.6Very high10 Ų1029.2 Ų29.25%0.05315%0.15CC..  trans-78.8162.8149.8-161.210.1000110.8T43 T236 K277 I334D39-T43 HydrophobicContact CB-CG2 4.38Å; D39-T43 WeakPolarHBondContact O-CB 3.46Å; D39-T43 WeakPolarHBondContact O-CG2 3.16Å; D39-T236 WeakPolarHBondContact OD1-CA 3.48Å; D39-T236 PolarHBondContact OD1-OG1 3.2Å; D39-K277 IonicContact OD1-NZ 3.93Å; D39-K277 PolarHBondContact OD1-NZ 3.44Å; D39-K277 VanDerWaalsContact OD1-NZ 3.1Å; D39-K277 IonicContact OD2-NZ 2.69Å; D39-K277 PolarHBondContact OD2-NZ 3.35Å; D39-I334 PolarHBondContact N-O 3.19Å
40M98.3Very high97.7Very high0 Ų029.9 Ų29.90%016%0.155CC..SBendtrans-93.3-69.3178.3-172.1-17675.200111.6T43 L44 A45 L234 T236 Y242 T243 I246 M247M40-T43 PolarHBondContact O-N 2.82Å; M40-L44 PolarHBondContact O-N 2.86Å; M40-A45 HydrophobicContact CG-CB 4.23Å; M40-A45 PolarHBondContact O-N 3.39Å; M40-L234 HydrophobicContact CB-CD1 4.22Å; M40-T236 HydrophobicContact CB-CG2 4.43Å; M40-Y242 HydrophobicContact CE-CD1 3.75Å; M40-Y242 HydrophobicContact CE-CE1 3.83Å; M40-T243 HydrophobicContact SD-CG2 3.78Å; M40-I246 HydrophobicContact CE-CG1 4.48Å; M40-I246 HydrophobicContact CG-CG2 4.35Å; M40-I246 HydrophobicContact SD-CB 4.14Å; M40-I246 HydrophobicContact SD-CG2 4.07Å; M40-M247 HydrophobicContact CG-SD 4.08Å; M40-M247 HydrophobicContact SD-CG 4.19Å; M40-M247 HydrophobicContact SD-SD 4.3Å
41D97.1Very high97.7Very high14 Ų1432.9 Ų32.98%0.07517%0.171CC..BIsolated β-bridgetrans-64133.6-171.6-66.5-56.9000111.2T43 Y47 F144 S238D41-T43 PolarHBondContact O-N 3.48Å; D41-T43 PolarHBondContact O-OG1 3.27Å; D41-Y47 HydrophobicContact CB-CE2 4.1Å; D41-Y47 PolarHBondContact OD1-OH 2.94Å; D41-F144 HydrophobicContact CB-CE2 4Å; D41-F144 HydrophobicContact CB-CZ 3.9Å; D41-S238 PolarHBondContact OD2-OG 2.83Å
42Y97.6Very high97.8Very high5 Ų527.6 Ų27.62%0.0215%0.146CC..THydrogen-bonded Turntrans53.79.4-175.2-72.5-70.5000116.4A45 M46 Y47 Y52 L143 F144Y42-A45 WeakPolarHBondContact CA-O 3.25Å; Y42-A45 PolarHBondContact N-O 2.9Å; Y42-M46 HydrophobicContact CD1-SD 3.99Å; Y42-M46 VanDerWaalsContact O-CE 3.29Å; Y42-M46 WeakPolarHBondContact O-CE 3.25Å; Y42-Y47 HydrophobicContact CD1-CD2 4.01Å; Y42-Y47 AromaticContact CD2-CD2 3.87Å; Y42-Y47 HydrophobicContact CD2-CD2 3.87Å; Y42-Y47 HydrophobicContact CD2-CE2 4.28Å; Y42-Y47 AromaticContact CE1-CD2 3.84Å; Y42-Y47 HydrophobicContact CE1-CD2 3.84Å; Y42-Y47 HydrophobicContact CE1-CG 4.3Å; Y42-Y47 AromaticContact CE2-CD2 3.68Å; Y42-Y47 HydrophobicContact CE2-CD2 3.68Å; Y42-Y47 HydrophobicContact CE2-CE2 4.31Å; Y42-Y47 HydrophobicContact CG-CD2 4.04Å; Y42-Y47 AromaticContact CZ-CD2 3.68Å; Y42-Y52 WeakPolarHBondContact OH-CD1 3.31Å; Y42-L143 HydrophobicContact CD1-CB 3.99Å; Y42-L143 HydrophobicContact CD1-CD1 3.31Å; Y42-L143 HydrophobicContact CD1-CG 4.28Å; Y42-L143 HydrophobicContact CD2-CB 3.88Å; Y42-L143 HydrophobicContact CD2-CD1 4.46Å; Y42-L143 HydrophobicContact CE1-CB 3.69Å; Y42-L143 HydrophobicContact CE1-CD1 3.58Å; Y42-L143 HydrophobicContact CE1-CG 4.25Å; Y42-L143 HydrophobicContact CE2-CB 3.58Å; Y42-L143 HydrophobicContact CG-CB 4.06Å; Y42-L143 HydrophobicContact CG-CD1 3.79Å; Y42-L143 VanDerWaalsContact CZ-CB 3.46Å; Y42-F144 AromaticContact CD2-CD2 3.96Å; Y42-F144 HydrophobicContact CD2-CD2 3.96Å; Y42-F144 HydrophobicContact CD2-CE1 4.44Å; Y42-F144 AromaticContact CD2-CE2 3.56Å; Y42-F144 HydrophobicContact CD2-CE2 3.56Å; Y42-F144 AromaticContact CD2-CZ 3.83Å; Y42-F144 HydrophobicContact CD2-CZ 3.83Å; Y42-F144 HydrophobicContact CE2-CD1 4Å; Y42-F144 AromaticContact CE2-CD2 3.87Å; Y42-F144 HydrophobicContact CE2-CD2 3.87Å; Y42-F144 AromaticContact CE2-CE1 3.86Å; Y42-F144 HydrophobicContact CE2-CE1 3.86Å; Y42-F144 AromaticContact CE2-CE2 3.72Å; Y42-F144 HydrophobicContact CE2-CE2 3.72Å; Y42-F144 HydrophobicContact CE2-CG 4.01Å; Y42-F144 AromaticContact CE2-CZ 3.72Å; Y42-F144 HydrophobicContact CE2-CZ 3.72Å
43T98.1Very high97.9Very high3 Ų323.4 Ų23.42%0.01812%0.123CC..THydrogen-bonded Turntrans-118.3-65.6179.9-61.20000111.1D39 M40 D41 I334 G335 D336 V356 C450D39-T43 HydrophobicContact CB-CG2 4.38Å; D39-T43 WeakPolarHBondContact O-CB 3.46Å; D39-T43 WeakPolarHBondContact O-CG2 3.16Å; M40-T43 PolarHBondContact O-N 2.82Å; D41-T43 PolarHBondContact O-N 3.48Å; D41-T43 PolarHBondContact O-OG1 3.27Å; T43-I334 HydrophobicContact CG2-CG2 3.86Å; T43-I334 WeakPolarHBondContact CG2-O 3.28Å; T43-G335 WeakPolarHBondContact OG1-CA 3.45Å; T43-D336 PolarHBondContact OG1-N 3.36Å; T43-D336 PolarHBondContact OG1-OD1 3.05Å; T43-V356 HydrophobicContact CG2-CG2 4.02Å; T43-C450 PolarHBondContact O-SG 3.47Å
44L97.9Very high97.9Very high6 Ų624.5 Ų24.53%0.03113%0.132CC..THydrogen-bonded Turntrans-89.8-42.9169.3-71.7174.2000110.7F38 M40 M46 I219 L234 M247 F268F38-L44 HydrophobicContact CB-CD1 3.72Å; F38-L44 HydrophobicContact CB-CG 4.11Å; F38-L44 HydrophobicContact CD1-CD1 4.29Å; F38-L44 HydrophobicContact CD1-CD2 3.67Å; F38-L44 HydrophobicContact CD1-CG 3.95Å; F38-L44 HydrophobicContact CE1-CD2 4.04Å; F38-L44 HydrophobicContact CG-CD1 4.12Å; F38-L44 HydrophobicContact CG-CD2 4.27Å; F38-L44 HydrophobicContact CG-CG 4.28Å; M40-L44 PolarHBondContact O-N 2.86Å; L44-M46 PolarHBondContact O-N 2.88Å; L44-I219 HydrophobicContact CD2-CG2 3.99Å; L44-I219 WeakPolarHBondContact O-CD1 3.29Å; L44-L234 HydrophobicContact CD1-CD1 3.94Å; L44-M247 HydrophobicContact CD1-CE 4.16Å; L44-F268 HydrophobicContact CD1-CZ 4.22Å
45A97.5Very high97.9Very high0 Ų019.8 Ų19.80%011%0.111CC..BIsolated β-bridgetrans-95.989178.400000109.7M40 Y42 Y47 I246 L250M40-A45 HydrophobicContact CG-CB 4.23Å; M40-A45 PolarHBondContact O-N 3.39Å; Y42-A45 WeakPolarHBondContact CA-O 3.25Å; Y42-A45 PolarHBondContact N-O 2.9Å; A45-Y47 PolarHBondContact O-N 2.89Å; A45-I246 HydrophobicContact CB-CG2 3.5Å; A45-I246 VanDerWaalsContact CB-CG2 3.5Å; A45-L250 HydrophobicContact CB-CD1 3.88Å
46M97.5Very high97.8Very high35 Ų3520.1 Ų20.117%0.17211%0.114CC..PPolyproline II helixtrans-78.2121.5176.2-164.360.962.400110.2Y42 L44 V214 V356 P358Y42-M46 HydrophobicContact CD1-SD 3.99Å; Y42-M46 VanDerWaalsContact O-CE 3.29Å; Y42-M46 WeakPolarHBondContact O-CE 3.25Å; L44-M46 PolarHBondContact O-N 2.88Å; M46-V214 HydrophobicContact CB-CB 4.07Å; M46-V214 HydrophobicContact CB-CG2 4.14Å; M46-V214 HydrophobicContact CG-CG2 4.26Å; M46-V214 PolarHBondContact O-N 3.01Å; M46-V356 HydrophobicContact CE-CG1 3.99Å; M46-P358 HydrophobicContact CE-CB 4.04Å; M46-P358 HydrophobicContact CE-CG 3.52Å; M46-P358 HydrophobicContact SD-CB 3.62Å; M46-P358 HydrophobicContact SD-CG 3.4Å; M46-P358 WeakPolarHBondContact SD-CG 3.38Å
47Y97.8Very high97.8Very high8 Ų820 Ų203%0.03111%0.114CC..BIsolated β-bridgetrans-82.3144.3175.1-60.8-75.4000111.4D41 Y42 A45 Y52 F144 T205 Y212 V213 Y242D41-Y47 HydrophobicContact CB-CE2 4.1Å; D41-Y47 PolarHBondContact OD1-OH 2.94Å; Y42-Y47 HydrophobicContact CD1-CD2 4.01Å; Y42-Y47 AromaticContact CD2-CD2 3.87Å; Y42-Y47 HydrophobicContact CD2-CD2 3.87Å; Y42-Y47 HydrophobicContact CD2-CE2 4.28Å; Y42-Y47 AromaticContact CE1-CD2 3.84Å; Y42-Y47 HydrophobicContact CE1-CD2 3.84Å; Y42-Y47 HydrophobicContact CE1-CG 4.3Å; Y42-Y47 AromaticContact CE2-CD2 3.68Å; Y42-Y47 HydrophobicContact CE2-CD2 3.68Å; Y42-Y47 HydrophobicContact CE2-CE2 4.31Å; Y42-Y47 HydrophobicContact CG-CD2 4.04Å; Y42-Y47 AromaticContact CZ-CD2 3.68Å; A45-Y47 PolarHBondContact O-N 2.89Å; Y47-Y52 HydrophobicContact CD1-CD1 4.28Å; Y47-Y52 AromaticContact CD1-CD2 3.57Å; Y47-Y52 HydrophobicContact CD1-CD2 3.57Å; Y47-Y52 HydrophobicContact CD1-CE1 4.14Å; Y47-Y52 AromaticContact CD1-CE2 3.38Å; Y47-Y52 HydrophobicContact CD1-CE2 3.38Å; Y47-Y52 HydrophobicContact CD1-CG 4Å; Y47-Y52 AromaticContact CD1-CZ 3.7Å; Y47-Y52 HydrophobicContact CD2-CD1 4.35Å; Y47-Y52 HydrophobicContact CD2-CE1 4.06Å; Y47-Y52 HydrophobicContact CE1-CD2 4.29Å; Y47-Y52 AromaticContact CE1-CE2 3.65Å; Y47-Y52 HydrophobicContact CE1-CE2 3.65Å; Y47-Y52 AromaticContact CE1-CZ 3.78Å; Y47-Y52 HydrophobicContact CE2-CE1 4.45Å; Y47-Y52 AromaticContact CG-CD1 3.87Å; Y47-Y52 HydrophobicContact CG-CD1 3.87Å; Y47-Y52 AromaticContact CG-CD2 3.97Å; Y47-Y52 HydrophobicContact CG-CD2 3.97Å; Y47-Y52 AromaticContact CG-CE1 3.89Å; Y47-Y52 HydrophobicContact CG-CE1 3.89Å; Y47-Y52 AromaticContact CG-CE2 3.97Å; Y47-Y52 HydrophobicContact CG-CE2 3.97Å; Y47-Y52 AromaticContact CG-CG 3.91Å; Y47-Y52 HydrophobicContact CG-CG 3.91Å; Y47-Y52 AromaticContact CG-CZ 3.94Å; Y47-F144 HydrophobicContact CE2-CE1 4.46Å; Y47-F144 HydrophobicContact CE2-CZ 4.05Å; Y47-T205 HydrophobicContact CE1-CG2 4.03Å; Y47-Y212 CarbonylContact C-O 3.59Å; Y47-Y212 WeakPolarHBondContact CA-O 3.49Å; Y47-V213 HydrophobicContact CD1-CG2 3.94Å; Y47-V213 HydrophobicContact CE1-CG2 3.88Å; Y47-Y242 WeakPolarHBondContact OH-CE1 3.08Å; Y47-Y242 PolarHBondContact OH-OH 3.31Å
48K97.9Very high97.8Very high77 Ų7723.9 Ų23.934%0.33513%0.132SC..PPolyproline II helixtrans-77.9124.5-178.6-64.8-167.6-170.2172.10110.8D51 Y52 E210 K211 Y212 V213 V214K48-D51 PolarHBondContact O-N 2.93Å; K48-Y52 WeakPolarHBondContact O-CB 3.3Å; K48-Y52 PolarHBondContact O-N 3.23Å; K48-E210 WeakPolarHBondContact CE-O 3.46Å; K48-E210 PolarHBondContact NZ-O 2.8Å; K48-K211 WeakPolarHBondContact CD-O 3.49Å; K48-Y212 PolarHBondContact N-O 3.14Å; K48-V213 WeakPolarHBondContact CE-O 3.09Å; K48-V214 HydrophobicContact CG-CG2 3.71Å
49S96.4Very high97.8Very high79 Ų7925.1 Ų25.155%0.55214%0.139SC*.THydrogen-bonded Turntrans-95.5139.2173.6-168.70000110.8E53S49-E53 VanDerWaalsContact CA-OE2 3.3Å; S49-E53 WeakPolarHBondContact CA-OE2 3.13Å; S49-E53 WeakPolarHBondContact CB-OE1 3.37Å; S49-E53 PolarHBondContact OG-OE1 3.21Å; S49-E53 PolarHBondContact OG-OE2 3.12Å
50P97.3Very high97.7Very high56 Ų5624.6 Ų24.636%0.36414%0.136SC..THydrogen-bonded Turncis-92.65.32.438.4-36.9000114.2Y52 E53 S54 Y78 P80P50-Y52 VanDerWaalsContact C-N 3.34Å; P50-Y52 PolarHBondContact O-N 3.27Å; P50-E53 PolarHBondContact O-N 2.92Å; P50-S54 VanDerWaalsContact O-CB 3.3Å; P50-S54 WeakPolarHBondContact O-CB 3.24Å; P50-S54 PolarHBondContact O-N 3.36Å; P50-Y78 HydrophobicContact CB-CD1 4.43Å; P50-Y78 HydrophobicContact CB-CE1 4.27Å; P50-P80 HydrophobicContact CB-CB 3.88Å; P50-P80 HydrophobicContact CB-CG 3.92Å; P50-P80 HydrophobicContact CG-CG 4.34Å
51D98.1Very high97.7Very high67 Ų6726.1 Ų26.136%0.35814%0.142SC..Hα-helixtrans-58.6-42-171.8-76.1-55.2000113.2K48 M55 Y212K48-D51 PolarHBondContact O-N 2.93Å; D51-M55 PolarHBondContact O-N 3.41Å; D51-M55 VanDerWaalsContact O-N 3.11Å; D51-Y212 HydrophobicContact CB-CD1 4.26Å; D51-Y212 HydrophobicContact CB-CE1 4.26Å
52Y97.8Very high97.8Very high9 Ų928.9 Ų28.94%0.03516%0.157CC..Hα-helixtrans-71.8-44.8-178.3-166.5-102.7000112Y42 Y47 K48 P50 S54 M55 G56 F144 T205 Y212Y42-Y52 WeakPolarHBondContact OH-CD1 3.31Å; Y47-Y52 HydrophobicContact CD1-CD1 4.28Å; Y47-Y52 AromaticContact CD1-CD2 3.57Å; Y47-Y52 HydrophobicContact CD1-CD2 3.57Å; Y47-Y52 HydrophobicContact CD1-CE1 4.14Å; Y47-Y52 AromaticContact CD1-CE2 3.38Å; Y47-Y52 HydrophobicContact CD1-CE2 3.38Å; Y47-Y52 HydrophobicContact CD1-CG 4Å; Y47-Y52 AromaticContact CD1-CZ 3.7Å; Y47-Y52 HydrophobicContact CD2-CD1 4.35Å; Y47-Y52 HydrophobicContact CD2-CE1 4.06Å; Y47-Y52 HydrophobicContact CE1-CD2 4.29Å; Y47-Y52 AromaticContact CE1-CE2 3.65Å; Y47-Y52 HydrophobicContact CE1-CE2 3.65Å; Y47-Y52 AromaticContact CE1-CZ 3.78Å; Y47-Y52 HydrophobicContact CE2-CE1 4.45Å; Y47-Y52 AromaticContact CG-CD1 3.87Å; Y47-Y52 HydrophobicContact CG-CD1 3.87Å; Y47-Y52 AromaticContact CG-CD2 3.97Å; Y47-Y52 HydrophobicContact CG-CD2 3.97Å; Y47-Y52 AromaticContact CG-CE1 3.89Å; Y47-Y52 HydrophobicContact CG-CE1 3.89Å; Y47-Y52 AromaticContact CG-CE2 3.97Å; Y47-Y52 HydrophobicContact CG-CE2 3.97Å; Y47-Y52 AromaticContact CG-CG 3.91Å; Y47-Y52 HydrophobicContact CG-CG 3.91Å; Y47-Y52 AromaticContact CG-CZ 3.94Å; K48-Y52 WeakPolarHBondContact O-CB 3.3Å; K48-Y52 PolarHBondContact O-N 3.23Å; P50-Y52 VanDerWaalsContact C-N 3.34Å; P50-Y52 PolarHBondContact O-N 3.27Å; Y52-S54 VanDerWaalsContact C-N 3.32Å; Y52-S54 PolarHBondContact O-N 3.25Å; Y52-M55 HydrophobicContact CD2-CE 3.64Å; Y52-M55 HydrophobicContact CE2-CE 3.65Å; Y52-M55 HydrophobicContact CG-CE 4.47Å; Y52-M55 PolarHBondContact O-N 3.39Å; Y52-G56 PolarHBondContact O-N 3Å; Y52-F144 HydrophobicContact CE1-CD1 4.16Å; Y52-F144 AromaticContact CE1-CE1 3.76Å; Y52-F144 HydrophobicContact CE1-CE1 3.76Å; Y52-T205 HydrophobicContact CE2-CG2 3.92Å; Y52-T205 WeakPolarHBondContact CE2-OG1 3.38Å; Y52-Y212 HydrophobicContact CD2-CD1 4.2Å; Y52-Y212 HydrophobicContact CD2-CG 4.29Å
53E97.8Very high97.8Very high9 Ų932.1 Ų32.14%0.04217%0.169CC..Hα-helixtrans-64.9-36.7176.6-59.295132.200111.7S49 P50 G56 F57 Y78 L146 S147S49-E53 VanDerWaalsContact CA-OE2 3.3Å; S49-E53 WeakPolarHBondContact CA-OE2 3.13Å; S49-E53 WeakPolarHBondContact CB-OE1 3.37Å; S49-E53 PolarHBondContact OG-OE1 3.21Å; S49-E53 PolarHBondContact OG-OE2 3.12Å; P50-E53 PolarHBondContact O-N 2.92Å; E53-G56 PolarHBondContact O-N 2.88Å; E53-F57 VanDerWaalsContact O-CB 3.28Å; E53-F57 WeakPolarHBondContact O-CB 3.22Å; E53-F57 PolarHBondContact O-N 3.38Å; E53-Y78 HydrophobicContact CB-CD1 4.14Å; E53-Y78 HydrophobicContact CB-CE1 3.44Å; E53-Y78 VanDerWaalsContact CB-CE1 3.44Å; E53-Y78 HydrophobicContact CB-CE2 4.21Å; E53-Y78 VanDerWaalsContact CB-CZ 3.49Å; E53-Y78 HydrophobicContact CG-CE1 4.39Å; E53-L146 HydrophobicContact CG-CB 4.26Å; E53-L146 HydrophobicContact CG-CD1 4.13Å; E53-S147 WeakPolarHBondContact CA-OG 3.47Å; E53-S147 PolarHBondContact O-OG 2.89Å
54S98.1Very high97.8Very high30 Ų3032 Ų3221%0.2117%0.168CC..Hα-helixtrans-64.2-44.7175.3-166.70000111.5P50 Y52 F57 E58P50-S54 VanDerWaalsContact O-CB 3.3Å; P50-S54 WeakPolarHBondContact O-CB 3.24Å; P50-S54 PolarHBondContact O-N 3.36Å; Y52-S54 VanDerWaalsContact C-N 3.32Å; Y52-S54 PolarHBondContact O-N 3.25Å; S54-F57 PolarHBondContact O-N 2.8Å; S54-E58 WeakPolarHBondContact O-CG 3.35Å; S54-E58 PolarHBondContact O-N 3.19Å
55M97.8Very high97.8Very high5 Ų532.6 Ų32.63%0.02517%0.172CC..Hα-helixtrans-60.7-47.1174.6178.4-173.359.900111.2D51 Y52 F57 E58 L59 L201 Q204 Y212D51-M55 PolarHBondContact O-N 3.41Å; D51-M55 VanDerWaalsContact O-N 3.11Å; Y52-M55 HydrophobicContact CD2-CE 3.64Å; Y52-M55 HydrophobicContact CE2-CE 3.65Å; Y52-M55 HydrophobicContact CG-CE 4.47Å; Y52-M55 PolarHBondContact O-N 3.39Å; M55-F57 VanDerWaalsContact C-N 3.3Å; M55-F57 PolarHBondContact O-N 2.9Å; M55-E58 PolarHBondContact O-N 3.11Å; M55-L59 HydrophobicContact CG-CD1 4.31Å; M55-L59 WeakPolarHBondContact O-CG 3.07Å; M55-L59 PolarHBondContact O-N 3.01Å; M55-L201 HydrophobicContact CE-CD1 3.47Å; M55-L201 VanDerWaalsContact CE-CD1 3.47Å; M55-L201 HydrophobicContact CE-CG 4.48Å; M55-Q204 HydrophobicContact SD-CB 3.64Å; M55-Y212 HydrophobicContact CB-CE1 4.13Å; M55-Y212 HydrophobicContact CE-CD1 4.27Å; M55-Y212 HydrophobicContact CE-CD2 4.5Å; M55-Y212 HydrophobicContact CE-CE1 4.22Å; M55-Y212 HydrophobicContact CE-CE2 4.42Å; M55-Y212 HydrophobicContact CE-CG 4.42Å; M55-Y212 HydrophobicContact SD-CD2 4.33Å; M55-Y212 HydrophobicContact SD-CE1 3.94Å; M55-Y212 HydrophobicContact SD-CE2 3.71Å
56G97.4Very high97.8Very high7 Ų736.2 Ų36.27%0.07220%0.197CC..Hα-helixtrans-59.5-40.9176.200000112.6Y52 E53 L60Y52-G56 PolarHBondContact O-N 3Å; E53-G56 PolarHBondContact O-N 2.88Å; G56-L60 WeakPolarHBondContact O-CB 3.37Å; G56-L60 VanDerWaalsContact O-CG 3.27Å; G56-L60 WeakPolarHBondContact O-CG 3.35Å; G56-L60 PolarHBondContact O-N 3.26Å
57F98.4Very high97.8Very high0 Ų038 Ų380%021%0.207CC..Hα-helixtrans-64.7-44.8176.8172.9-92.1000112.6E53 S54 M55 L60 R61 Y76 Y78 Y150 L151E53-F57 VanDerWaalsContact O-CB 3.28Å; E53-F57 WeakPolarHBondContact O-CB 3.22Å; E53-F57 PolarHBondContact O-N 3.38Å; S54-F57 PolarHBondContact O-N 2.8Å; M55-F57 VanDerWaalsContact C-N 3.3Å; M55-F57 PolarHBondContact O-N 2.9Å; F57-L60 PolarHBondContact O-N 3.4Å; F57-R61 HydrophobicContact CE1-CB 4.48Å; F57-R61 VanDerWaalsContact O-CB 3.25Å; F57-R61 WeakPolarHBondContact O-CB 3.33Å; F57-R61 PolarHBondContact O-N 3.46Å; F57-Y76 WeakPolarHBondContact CE1-O 3.34Å; F57-Y78 HydrophobicContact CB-CD2 3.81Å; F57-Y78 HydrophobicContact CB-CG 4.16Å; F57-Y78 HydrophobicContact CD2-CD2 4.11Å; F57-Y78 AromaticContact CG-CD2 3.95Å; F57-Y78 HydrophobicContact CG-CD2 3.95Å; F57-Y78 HydrophobicContact CG-CG 4.37Å; F57-Y150 AromaticContact CD2-CD1 3.71Å; F57-Y150 HydrophobicContact CD2-CD1 3.71Å; F57-Y150 HydrophobicContact CD2-CE1 4.4Å; F57-Y150 AromaticContact CE2-CD1 3.42Å; F57-Y150 HydrophobicContact CE2-CD1 3.42Å; F57-Y150 VanDerWaalsContact CE2-CD1 3.42Å; F57-Y150 AromaticContact CE2-CE1 3.81Å; F57-Y150 HydrophobicContact CE2-CE1 3.81Å; F57-Y150 HydrophobicContact CZ-CD1 4.04Å; F57-Y150 AromaticContact CZ-CE1 3.95Å; F57-Y150 HydrophobicContact CZ-CE1 3.95Å; F57-L151 HydrophobicContact CD2-CB 4.03Å; F57-L151 HydrophobicContact CE2-CB 3.86Å; F57-L151 HydrophobicContact CE2-CD1 3.96Å; F57-L151 HydrophobicContact CZ-CD1 4.45Å
58E98.1Very high97.8Very high82 Ų8240.8 Ų40.838%0.38324%0.238SC..Hα-helixtrans-61.5-46.8177.8-74.3169.6-163.100111.3S54 M55 L60 R61 D62S54-E58 WeakPolarHBondContact O-CG 3.35Å; S54-E58 PolarHBondContact O-N 3.19Å; M55-E58 PolarHBondContact O-N 3.11Å; E58-L60 PolarHBondContact O-N 3.33Å; E58-R61 PolarHBondContact O-N 3.39Å; E58-D62 WeakPolarHBondContact O-CB 3.38Å; E58-D62 PolarHBondContact O-N 3.02Å
59L97.9Very high97.8Very high25 Ų2537.9 Ų37.913%0.13122%0.224CC..Hα-helixtrans-59.6-44.8176.3-70.3174.6000112M55 R63 I195 T200 L201M55-L59 HydrophobicContact CG-CD1 4.31Å; M55-L59 WeakPolarHBondContact O-CG 3.07Å; M55-L59 PolarHBondContact O-N 3.01Å; L59-R63 VanDerWaalsContact O-CB 3.28Å; L59-R63 WeakPolarHBondContact O-CB 3.46Å; L59-R63 PolarHBondContact O-N 2.94Å; L59-I195 HydrophobicContact CB-CD1 3.84Å; L59-I195 HydrophobicContact CB-CG1 4.43Å; L59-I195 HydrophobicContact CB-CG2 4.5Å; L59-I195 HydrophobicContact CD1-CG2 4.21Å; L59-T200 HydrophobicContact CD1-CG2 4.46Å; L59-T200 HydrophobicContact CD2-CG2 3.96Å; L59-L201 HydrophobicContact CD1-CB 4.24Å; L59-L201 HydrophobicContact CD1-CD1 3.9Å
60L97.7Very high97.9Very high0 Ų035 Ų350%020%0.204CC..Hα-helixtrans-61.8-51.8176.1-75.7168.3000111.6G56 F57 E58 D62 R63 M64 E148 L151 A191 M192 I195G56-L60 WeakPolarHBondContact O-CB 3.37Å; G56-L60 VanDerWaalsContact O-CG 3.27Å; G56-L60 WeakPolarHBondContact O-CG 3.35Å; G56-L60 PolarHBondContact O-N 3.26Å; F57-L60 PolarHBondContact O-N 3.4Å; E58-L60 PolarHBondContact O-N 3.33Å; L60-D62 VanDerWaalsContact C-N 3.29Å; L60-D62 PolarHBondContact O-N 2.81Å; L60-R63 WeakPolarHBondContact O-CB 3.26Å; L60-R63 PolarHBondContact O-N 3.44Å; L60-R63 VanDerWaalsContact O-N 3.14Å; L60-M64 VanDerWaalsContact O-CG 3.3Å; L60-M64 WeakPolarHBondContact O-CG 3.15Å; L60-M64 PolarHBondContact O-N 3.39Å; L60-E148 HydrophobicContact CD1-CG 3.95Å; L60-L151 HydrophobicContact CB-CD2 3.58Å; L60-L151 HydrophobicContact CD1-CD2 4.24Å; L60-L151 HydrophobicContact CG-CD2 4.45Å; L60-A191 HydrophobicContact CD2-CB 4.2Å; L60-M192 HydrophobicContact CD1-CE 3.54Å; L60-M192 HydrophobicContact CD2-CB 3.75Å; L60-M192 HydrophobicContact CD2-CE 3.84Å; L60-M192 HydrophobicContact CD2-CG 4.49Å; L60-M192 HydrophobicContact CD2-SD 4.14Å; L60-M192 HydrophobicContact CG-CE 3.88Å; L60-I195 HydrophobicContact CB-CD1 4.35Å; L60-I195 HydrophobicContact CD2-CD1 3.76Å; L60-I195 HydrophobicContact CG-CD1 3.97Å
61R98Very high97.9Very high31 Ų3138.9 Ų38.912%0.11722%0.217CC..Hα-helixtrans-55.1-47-179.8178.7-161.172-160.4-11.3110.8F57 E58 R63 M64 V65 I73 L74 Y76 L151F57-R61 HydrophobicContact CE1-CB 4.48Å; F57-R61 VanDerWaalsContact O-CB 3.25Å; F57-R61 WeakPolarHBondContact O-CB 3.33Å; F57-R61 PolarHBondContact O-N 3.46Å; E58-R61 PolarHBondContact O-N 3.39Å; R61-R63 VanDerWaalsContact C-N 3.35Å; R61-M64 PolarHBondContact O-N 3.35Å; R61-V65 PolarHBondContact O-N 2.76Å; R61-I73 WeakPolarHBondContact CD-O 3.39Å; R61-I73 HydrophobicContact CG-CG1 4.31Å; R61-L74 HydrophobicContact CG-CD2 4.38Å; R61-L74 PolarHBondContact NH1-O 2.81Å; R61-Y76 PolarHBondContact NH1-O 2.93Å; R61-L151 HydrophobicContact CB-CD1 4.45Å
62D98Very high97.8Very high73 Ų7339 Ų3939%0.3922%0.215SC..Hα-helixtrans-68.3-37.4-179.1-64.7-1.5000110.9E58 L60 V65 S66 L74E58-D62 WeakPolarHBondContact O-CB 3.38Å; E58-D62 PolarHBondContact O-N 3.02Å; L60-D62 VanDerWaalsContact C-N 3.29Å; L60-D62 PolarHBondContact O-N 2.81Å; D62-V65 PolarHBondContact O-N 3.26Å; D62-S66 PolarHBondContact O-N 3.41Å; D62-L74 WeakPolarHBondContact OD1-CD2 3.36Å
63R97.8Very high97.8Very high73 Ų7338.6 Ų38.628%0.27521%0.214SC..Hα-helixtrans-61.7-45.3172.7178.357-177.8161.4-5.2111.8L59 L60 R61 V65 S66 I67 A191 F194 I195L59-R63 VanDerWaalsContact O-CB 3.28Å; L59-R63 WeakPolarHBondContact O-CB 3.46Å; L59-R63 PolarHBondContact O-N 2.94Å; L60-R63 WeakPolarHBondContact O-CB 3.26Å; L60-R63 PolarHBondContact O-N 3.44Å; L60-R63 VanDerWaalsContact O-N 3.14Å; R61-R63 VanDerWaalsContact C-N 3.35Å; R63-V65 VanDerWaalsContact C-N 3.31Å; R63-V65 PolarHBondContact O-N 2.83Å; R63-S66 WeakPolarHBondContact CD-OG 3.33Å; R63-S66 PolarHBondContact NH1-OG 3.03Å; R63-S66 VanDerWaalsContact NH1-OG 3.16Å; R63-S66 WeakPolarHBondContact O-CB 3.42Å; R63-S66 PolarHBondContact O-N 3.32Å; R63-S66 VanDerWaalsContact O-N 3.1Å; R63-S66 PolarHBondContact O-OG 2.68Å; R63-I67 PolarHBondContact O-N 3.18Å; R63-A191 HydrophobicContact CB-CB 4.27Å; R63-A191 HydrophobicContact CG-CB 3.62Å; R63-F194 HydrophobicContact CG-CD1 4.24Å; R63-I195 HydrophobicContact CB-CD1 4.3Å
64M98.4Very high97.7Very high0 Ų041.6 Ų41.60%023%0.23CC..Hα-helixtrans-56.8-44.7177.3-66.5-57.7-77.100111.3L60 R61 S66 I67 G68 Y69 I73 L151 L155 D187 V188 A191L60-M64 VanDerWaalsContact O-CG 3.3Å; L60-M64 WeakPolarHBondContact O-CG 3.15Å; L60-M64 PolarHBondContact O-N 3.39Å; R61-M64 PolarHBondContact O-N 3.35Å; M64-S66 PolarHBondContact O-N 3.17Å; M64-I67 WeakPolarHBondContact O-CG1 3.4Å; M64-I67 PolarHBondContact O-N 3.07Å; M64-I67 HydrophobicContact SD-CD1 4.2Å; M64-G68 PolarHBondContact O-N 3.23Å; M64-Y69 HydrophobicContact CB-CD2 4.36Å; M64-Y69 HydrophobicContact CB-CG 4.23Å; M64-Y69 HydrophobicContact CE-CD1 3.98Å; M64-Y69 HydrophobicContact CE-CD2 3.73Å; M64-Y69 HydrophobicContact CE-CE1 3.64Å; M64-Y69 HydrophobicContact CE-CE2 3.38Å; M64-Y69 HydrophobicContact CE-CG 4.03Å; M64-Y69 VanDerWaalsContact O-CB 3.28Å; M64-Y69 WeakPolarHBondContact O-CB 3.22Å; M64-Y69 WeakPolarHBondContact O-CD2 3.39Å; M64-Y69 PolarHBondContact O-N 3.37Å; M64-Y69 VanDerWaalsContact O-N 3.07Å; M64-I73 HydrophobicContact CB-CD1 3.88Å; M64-L151 HydrophobicContact CG-CD2 3.98Å; M64-L155 HydrophobicContact CE-CD1 3.93Å; M64-D187 HydrophobicContact CE-CB 3.88Å; M64-D187 HydrophobicContact SD-CB 4.48Å; M64-V188 HydrophobicContact CE-CG2 3.77Å; M64-V188 HydrophobicContact SD-CG2 4.2Å; M64-A191 HydrophobicContact SD-CB 3.77Å
65V98.4Very high97.7Very high18 Ų1847.4 Ų47.411%0.10925%0.247CC..Hα-helixtrans-64.4-41.2176.2177.80000111.5R61 D62 R63 I67 G68 I73 L74R61-V65 PolarHBondContact O-N 2.76Å; D62-V65 PolarHBondContact O-N 3.26Å; R63-V65 VanDerWaalsContact C-N 3.31Å; R63-V65 PolarHBondContact O-N 2.83Å; V65-I67 PolarHBondContact O-N 2.85Å; V65-G68 PolarHBondContact O-N 2.92Å; V65-I73 HydrophobicContact CG2-CD1 3.62Å; V65-I73 HydrophobicContact CG2-CG1 3.44Å; V65-I73 VanDerWaalsContact CG2-CG1 3.44Å; V65-L74 HydrophobicContact CB-CD2 4.35Å; V65-L74 HydrophobicContact CG2-CD2 3.76Å; V65-L74 HydrophobicContact CG2-CG 3.9Å
66S97.8Very high97.7Very high76 Ų7648.1 Ų48.153%0.53125%0.25SC..Hα-helixtrans-61-25.9179.280.60000113.9D62 R63 M64D62-S66 PolarHBondContact O-N 3.41Å; R63-S66 WeakPolarHBondContact CD-OG 3.33Å; R63-S66 PolarHBondContact NH1-OG 3.03Å; R63-S66 VanDerWaalsContact NH1-OG 3.16Å; R63-S66 WeakPolarHBondContact O-CB 3.42Å; R63-S66 PolarHBondContact O-N 3.32Å; R63-S66 VanDerWaalsContact O-N 3.1Å; R63-S66 PolarHBondContact O-OG 2.68Å; M64-S66 PolarHBondContact O-N 3.17Å
67I97.3Very high97.7Very high74 Ų7452.4 Ų52.438%0.37928%0.275SS..THydrogen-bonded Turntrans-93.64.1177.664.8170.8000113.2R63 M64 V65 Y69 D187R63-I67 PolarHBondContact O-N 3.18Å; M64-I67 WeakPolarHBondContact O-CG1 3.4Å; M64-I67 PolarHBondContact O-N 3.07Å; M64-I67 HydrophobicContact SD-CD1 4.2Å; V65-I67 PolarHBondContact O-N 2.85Å; I67-Y69 HydrophobicContact CD1-CD2 4.28Å; I67-Y69 HydrophobicContact CD1-CE2 4.23Å; I67-Y69 HydrophobicContact CG1-CD2 4.1Å; I67-D187 HydrophobicContact CD1-CB 4.39Å
68G97.2Very high97.7Very high66 Ų6653.3 Ų53.368%0.6828%0.278SS*.THydrogen-bonded Turntrans111.45.9171.700000115.7M64 V65M64-G68 PolarHBondContact O-N 3.23Å; V65-G68 PolarHBondContact O-N 2.92Å
69Y98.3Very high97.7Very high15 Ų1552 Ų526%0.05927%0.274CS..  trans-67.6154.2171.3-80.8-111.2000111.5M64 I67 H71 L155 F159 M179 M184 D187M64-Y69 HydrophobicContact CB-CD2 4.36Å; M64-Y69 HydrophobicContact CB-CG 4.23Å; M64-Y69 HydrophobicContact CE-CD1 3.98Å; M64-Y69 HydrophobicContact CE-CD2 3.73Å; M64-Y69 HydrophobicContact CE-CE1 3.64Å; M64-Y69 HydrophobicContact CE-CE2 3.38Å; M64-Y69 HydrophobicContact CE-CG 4.03Å; M64-Y69 VanDerWaalsContact O-CB 3.28Å; M64-Y69 WeakPolarHBondContact O-CB 3.22Å; M64-Y69 WeakPolarHBondContact O-CD2 3.39Å; M64-Y69 PolarHBondContact O-N 3.37Å; M64-Y69 VanDerWaalsContact O-N 3.07Å; I67-Y69 HydrophobicContact CD1-CD2 4.28Å; I67-Y69 HydrophobicContact CD1-CE2 4.23Å; I67-Y69 HydrophobicContact CG1-CD2 4.1Å; Y69-H71 PolarHBondContact O-N 2.77Å; Y69-L155 HydrophobicContact CD1-CD2 4Å; Y69-L155 HydrophobicContact CE1-CD1 4.43Å; Y69-L155 HydrophobicContact CE1-CD2 4.29Å; Y69-F159 HydrophobicContact CD1-CE2 4.15Å; Y69-F159 AromaticContact CD1-CZ 3.95Å; Y69-F159 HydrophobicContact CD1-CZ 3.95Å; Y69-F159 HydrophobicContact CE1-CE2 4.07Å; Y69-F159 HydrophobicContact CE1-CZ 4.12Å; Y69-M179 HydrophobicContact CE1-SD 4.02Å; Y69-M184 HydrophobicContact CE1-CG 4.21Å; Y69-M184 WeakPolarHBondContact OH-CA 3.32Å; Y69-D187 HydrophobicContact CE2-CB 3.99Å; Y69-D187 WeakPolarHBondContact CE2-OD2 3.26Å; Y69-D187 WeakPolarHBondContact OH-CB 3.23Å; Y69-D187 PolarHBondContact OH-OD2 2.87Å
70P97.4Very high97.6Very high20 Ų2053.8 Ų53.813%0.1329%0.287CS..  trans-59.9135.1-175.6-25.937.2000113.3E72 I73 F158 F159 Y165P70-E72 WeakPolarHBondContact CB-OE2 3.45Å; P70-E72 PolarHBondContact O-N 3.04Å; P70-E72 VanDerWaalsContact O-N 3.08Å; P70-I73 VanDerWaalsContact O-CG1 3.31Å; P70-I73 WeakPolarHBondContact O-CG1 3.36Å; P70-I73 PolarHBondContact O-N 2.98Å; P70-I73 VanDerWaalsContact O-N 3.12Å; P70-F158 HydrophobicContact CB-CE1 3.96Å; P70-F158 HydrophobicContact CB-CZ 3.87Å; P70-F158 HydrophobicContact CG-CE1 3.89Å; P70-F158 HydrophobicContact CG-CZ 4.29Å; P70-F159 HydrophobicContact CG-CE1 4.14Å; P70-F159 HydrophobicContact CG-CZ 4.28Å; P70-Y165 WeakPolarHBondContact CG-OH 3.4Å
71H97.3Very high97.6Very high137 Ų13756 Ų5663%0.63430%0.303SS*.G310 helixtrans-61.3-22.9-176.4-7268.7000113Y69 I73 L74Y69-H71 PolarHBondContact O-N 2.77Å; H71-I73 PolarHBondContact O-N 3.44Å; H71-I73 VanDerWaalsContact O-N 3.09Å; H71-L74 VanDerWaalsContact O-CB 3.3Å; H71-L74 WeakPolarHBondContact O-CB 3.28Å; H71-L74 WeakPolarHBondContact O-CG 3.34Å; H71-L74 PolarHBondContact O-N 2.79Å
72E96.9Very high97.6Very high68 Ų6854.6 Ų54.632%0.31830%0.297SS..G310 helixtrans-59.9-19.6177.5-60.893.8140.800112.8P70 L74 R75 F158 R164P70-E72 WeakPolarHBondContact CB-OE2 3.45Å; P70-E72 PolarHBondContact O-N 3.04Å; P70-E72 VanDerWaalsContact O-N 3.08Å; E72-L74 PolarHBondContact O-N 2.81Å; E72-R75 WeakPolarHBondContact O-CD 3.41Å; E72-R75 WeakPolarHBondContact O-CG 3.26Å; E72-R75 PolarHBondContact O-N 3.14Å; E72-R75 PolarHBondContact O-NE 2.98Å; E72-F158 HydrophobicContact CB-CE2 3.56Å; E72-F158 HydrophobicContact CB-CZ 3.97Å; E72-F158 HydrophobicContact CG-CE2 4.42Å; E72-R164 IonicContact OE1-CZ 2.65Å; E72-R164 VanDerWaalsContact OE1-CZ 3.25Å; E72-R164 IonicContact OE1-NH1 3.35Å; E72-R164 PolarHBondContact OE1-NH1 3.41Å; E72-R164 IonicContact OE1-NH2 2.74Å; E72-R164 PolarHBondContact OE1-NH2 3.04Å; E72-R164 IonicContact OE2-NH2 3.04Å
73I96.9Very high97.6Very high1 Ų151.7 Ų51.71%0.00528%0.283CS..G310 helixtrans-70.4-17.917575.9-176.8000112.9R61 M64 V65 P70 H71 R75 Y76 L155 F158R61-I73 WeakPolarHBondContact CD-O 3.39Å; R61-I73 HydrophobicContact CG-CG1 4.31Å; M64-I73 HydrophobicContact CB-CD1 3.88Å; V65-I73 HydrophobicContact CG2-CD1 3.62Å; V65-I73 HydrophobicContact CG2-CG1 3.44Å; V65-I73 VanDerWaalsContact CG2-CG1 3.44Å; P70-I73 VanDerWaalsContact O-CG1 3.31Å; P70-I73 WeakPolarHBondContact O-CG1 3.36Å; P70-I73 PolarHBondContact O-N 2.98Å; P70-I73 VanDerWaalsContact O-N 3.12Å; H71-I73 PolarHBondContact O-N 3.44Å; H71-I73 VanDerWaalsContact O-N 3.09Å; I73-R75 PolarHBondContact O-N 3Å; I73-R75 VanDerWaalsContact O-N 3.11Å; I73-Y76 HydrophobicContact CB-CD2 4.3Å; I73-Y76 WeakPolarHBondContact O-CD2 3.29Å; I73-Y76 PolarHBondContact O-N 3.02Å; I73-Y76 VanDerWaalsContact O-N 3.1Å; I73-L155 HydrophobicContact CD1-CD2 4.18Å; I73-L155 HydrophobicContact CG2-CD2 4.14Å; I73-F158 HydrophobicContact CG2-CD1 4.12Å; I73-F158 HydrophobicContact CG2-CD2 4.4Å; I73-F158 HydrophobicContact CG2-CE1 4.36Å; I73-F158 HydrophobicContact CG2-CG 4.14Å
74L97.4Very high97.6Very high72 Ų7249.1 Ų49.138%0.37728%0.275SS..G310 helixtrans-60.8-20.2175.6-65.7175.8000112.9R61 D62 V65 H71 E72 Y76R61-L74 HydrophobicContact CG-CD2 4.38Å; R61-L74 PolarHBondContact NH1-O 2.81Å; D62-L74 WeakPolarHBondContact OD1-CD2 3.36Å; V65-L74 HydrophobicContact CB-CD2 4.35Å; V65-L74 HydrophobicContact CG2-CD2 3.76Å; V65-L74 HydrophobicContact CG2-CG 3.9Å; H71-L74 VanDerWaalsContact O-CB 3.3Å; H71-L74 WeakPolarHBondContact O-CB 3.28Å; H71-L74 WeakPolarHBondContact O-CG 3.34Å; H71-L74 PolarHBondContact O-N 2.79Å; E72-L74 PolarHBondContact O-N 2.81Å; L74-Y76 PolarHBondContact O-N 2.91Å
75R96.6Very high97.6Very high152 Ų15249.4 Ų49.457%0.57428%0.276SS*.G310 helixtrans-71.8-17177.779.7-163.6169.5-169.8-1.7113.9E72 I73E72-R75 WeakPolarHBondContact O-CD 3.41Å; E72-R75 WeakPolarHBondContact O-CG 3.26Å; E72-R75 PolarHBondContact O-N 3.14Å; E72-R75 PolarHBondContact O-NE 2.98Å; I73-R75 PolarHBondContact O-N 3Å; I73-R75 VanDerWaalsContact O-N 3.11Å
76Y97.8Very high97.4Very high21 Ų2149.1 Ų49.18%0.08228%0.277CS..  trans-75.2137.8178.8-71.1-76.7000110.1F57 R61 I73 L74 F112 C154 D157 F158 R161F57-Y76 WeakPolarHBondContact CE1-O 3.34Å; R61-Y76 PolarHBondContact NH1-O 2.93Å; I73-Y76 HydrophobicContact CB-CD2 4.3Å; I73-Y76 WeakPolarHBondContact O-CD2 3.29Å; I73-Y76 PolarHBondContact O-N 3.02Å; I73-Y76 VanDerWaalsContact O-N 3.1Å; L74-Y76 PolarHBondContact O-N 2.91Å; Y76-F112 HydrophobicContact CE1-CE2 4.05Å; Y76-C154 HydrophobicContact CD1-CB 4Å; Y76-C154 HydrophobicContact CD2-CB 3.99Å; Y76-C154 HydrophobicContact CE1-CB 4.09Å; Y76-C154 HydrophobicContact CE2-CB 4.1Å; Y76-C154 HydrophobicContact CG-CB 3.95Å; Y76-D157 PolarHBondContact OH-OD2 2.97Å; Y76-F158 HydrophobicContact CE2-CB 4.1Å; Y76-F158 HydrophobicContact CE2-CD2 4.46Å; Y76-R161 PolarHBondContact OH-NH2 2.89Å
77T97.8Very high97.4Very high96 Ų9645.6 Ų45.659%0.58925%0.252SS*.  trans-117.2148.9170.155.20000108.7D79 Y150T77-D79 PolarHBondContact O-N 2.76Å; T77-Y150 WeakPolarHBondContact O-CE1 3.43Å; T77-Y150 PolarHBondContact O-OH 3.19Å; T77-Y150 VanDerWaalsContact O-OH 3.06Å
78Y98.5Very high97.4Very high20 Ų2042 Ų428%0.07823%0.234CC..  trans-61.6130.2-179.8-175-111000111.2P50 E53 F57 P80 P83 Y150P50-Y78 HydrophobicContact CB-CD1 4.43Å; P50-Y78 HydrophobicContact CB-CE1 4.27Å; E53-Y78 HydrophobicContact CB-CD1 4.14Å; E53-Y78 HydrophobicContact CB-CE1 3.44Å; E53-Y78 VanDerWaalsContact CB-CE1 3.44Å; E53-Y78 HydrophobicContact CB-CE2 4.21Å; E53-Y78 VanDerWaalsContact CB-CZ 3.49Å; E53-Y78 HydrophobicContact CG-CE1 4.39Å; F57-Y78 HydrophobicContact CB-CD2 3.81Å; F57-Y78 HydrophobicContact CB-CG 4.16Å; F57-Y78 HydrophobicContact CD2-CD2 4.11Å; F57-Y78 AromaticContact CG-CD2 3.95Å; F57-Y78 HydrophobicContact CG-CD2 3.95Å; F57-Y78 HydrophobicContact CG-CG 4.37Å; Y78-P80 HydrophobicContact CD1-CB 4.49Å; Y78-P80 HydrophobicContact CE1-CB 3.86Å; Y78-P83 HydrophobicContact CE2-CG 4.24Å; Y78-P83 WeakPolarHBondContact OH-CG 3.37Å; Y78-Y150 AromaticContact CD2-CD1 3.65Å; Y78-Y150 HydrophobicContact CD2-CD1 3.65Å; Y78-Y150 HydrophobicContact CD2-CE1 4.39Å; Y78-Y150 HydrophobicContact CD2-CG 4.13Å; Y78-Y150 HydrophobicContact CE2-CD1 4.22Å; Y78-Y150 HydrophobicContact CE2-CG 4.24Å
79D98.2Very high97.5Very high53 Ų5339 Ų3928%0.28320%0.201SC..  trans-114.5105.6173.5177.65.4000109.2T77 S81 F82 P83 Y150 Q421T77-D79 PolarHBondContact O-N 2.76Å; D79-S81 PolarHBondContact O-N 3.01Å; D79-S81 VanDerWaalsContact O-N 3.17Å; D79-S81 WeakPolarHBondContact OD1-CB 3.06Å; D79-S81 PolarHBondContact OD1-N 2.92Å; D79-S81 PolarHBondContact OD1-OG 3.25Å; D79-S81 PolarHBondContact OD2-OG 3.16Å; D79-F82 PolarHBondContact O-N 3.43Å; D79-P83 WeakPolarHBondContact O-CD 3.16Å; D79-Y150 HydrophobicContact CB-CE1 4.37Å; D79-Y150 HydrophobicContact CB-CE2 3.71Å; D79-Y150 WeakPolarHBondContact CB-OH 3.34Å; D79-Q421 PolarHBondContact OD2-NE2 2.86Å
80P97.1Very high97.5Very high64 Ų6438.2 Ų38.242%0.41620%0.199SC..THydrogen-bonded Turntrans-69.6-8.8-179.530-35.7000113.4P50 Y78 F82P50-P80 HydrophobicContact CB-CB 3.88Å; P50-P80 HydrophobicContact CB-CG 3.92Å; P50-P80 HydrophobicContact CG-CG 4.34Å; Y78-P80 HydrophobicContact CD1-CB 4.49Å; Y78-P80 HydrophobicContact CE1-CB 3.86Å; P80-F82 VanDerWaalsContact C-N 3.33Å
81S96.9Very high97.5Very high47 Ų4738.5 Ų38.533%0.32920%0.198SC..THydrogen-bonded Turntrans-77.9-19178.179.50000113.2D79 G420 Q421D79-S81 PolarHBondContact O-N 3.01Å; D79-S81 VanDerWaalsContact O-N 3.17Å; D79-S81 WeakPolarHBondContact OD1-CB 3.06Å; D79-S81 PolarHBondContact OD1-N 2.92Å; D79-S81 PolarHBondContact OD1-OG 3.25Å; D79-S81 PolarHBondContact OD2-OG 3.16Å; S81-G420 CarbonylContact O-C 3.55Å; S81-G420 WeakPolarHBondContact O-CA 3.41Å; S81-Q421 PolarHBondContact O-N 2.89Å; S81-Q421 PolarHBondContact OG-NE2 3.47Å
82F98.3Very high97.6Very high0 Ų033.6 Ų33.60%018%0.177CC..SBendtrans-84.4-61.1-176.2178.9-89000114D79 P80 L96 F112 F114 Y150 A153 Q421 M422D79-F82 PolarHBondContact O-N 3.43Å; P80-F82 VanDerWaalsContact C-N 3.33Å; F82-L96 HydrophobicContact CE1-CD1 3.89Å; F82-L96 HydrophobicContact CZ-CD1 4.08Å; F82-F112 AromaticContact CD2-CD1 3.8Å; F82-F112 HydrophobicContact CD2-CD1 3.8Å; F82-F112 HydrophobicContact CD2-CE1 4.11Å; F82-F112 AromaticContact CE2-CD1 3.62Å; F82-F112 HydrophobicContact CE2-CD1 3.62Å; F82-F112 HydrophobicContact CE2-CE1 4.16Å; F82-F112 HydrophobicContact CG-CD1 4.44Å; F82-F112 HydrophobicContact CG-CE1 4.29Å; F82-F112 HydrophobicContact CZ-CD1 4.08Å; F82-F112 HydrophobicContact CZ-CE1 4.36Å; F82-F114 HydrophobicContact CD2-CZ 4.49Å; F82-F114 HydrophobicContact CE2-CE2 4.28Å; F82-F114 HydrophobicContact CE2-CZ 4.05Å; F82-Y150 HydrophobicContact CB-CD2 3.8Å; F82-Y150 HydrophobicContact CB-CE2 3.97Å; F82-Y150 AromaticContact CD1-CD2 3.73Å; F82-Y150 HydrophobicContact CD1-CD2 3.73Å; F82-Y150 HydrophobicContact CD1-CE2 4.48Å; F82-Y150 AromaticContact CG-CD2 3.97Å; F82-Y150 HydrophobicContact CG-CD2 3.97Å; F82-Y150 HydrophobicContact CG-CE2 4.31Å; F82-A153 HydrophobicContact CD1-CB 4.37Å; F82-A153 HydrophobicContact CE1-CB 3.5Å; F82-A153 VanDerWaalsContact CE1-CB 3.5Å; F82-A153 HydrophobicContact CZ-CB 3.64Å; F82-Q421 HydrophobicContact CD2-CB 4.23Å; F82-M422 HydrophobicContact CE1-CE 4.46Å; F82-M422 HydrophobicContact CZ-CE 4.2Å; F82-M422 WeakPolarHBondContact O-CB 3.25Å; F82-M422 WeakPolarHBondContact O-CG 3.4Å; F82-M422 PolarHBondContact O-N 3.44Å
83P97.6Very high97.6Very high13 Ų1330.7 Ų30.78%0.08416%0.164CC..  trans-76.8136.5-169.832.6-35.3000111.7Y78 D79 L146 T149Y78-P83 HydrophobicContact CE2-CG 4.24Å; Y78-P83 WeakPolarHBondContact OH-CG 3.37Å; D79-P83 WeakPolarHBondContact O-CD 3.16Å; P83-L146 HydrophobicContact CB-CD2 4.04Å; P83-L146 HydrophobicContact CG-CB 4.42Å; P83-L146 HydrophobicContact CG-CD2 4.4Å; P83-T149 HydrophobicContact CB-CG2 4.03Å
84T97.8Very high97.7Very high18 Ų1830.7 Ų30.711%0.1116%0.164CC..  trans-114.4145.5164.1-60.90000107.5I87 M422 G423 L425T84-I87 WeakPolarHBondContact O-CG1 3.2Å; T84-M422 WeakPolarHBondContact OG1-CB 3.33Å; T84-G423 WeakPolarHBondContact CG2-O 3.12Å; T84-G423 PolarHBondContact OG1-O 2.92Å; T84-L425 HydrophobicContact CG2-CB 4.15Å; T84-L425 HydrophobicContact CG2-CD1 4.45Å
85R97.4Very high97.7Very high7 Ų727.2 Ų27.23%0.02615%0.146CC..THydrogen-bonded Turntrans-68.6154.9176.4-173.2164.862.6118.1-14.7111.7N141 T142 L146 D336 E359 L425R85-N141 VanDerWaalsContact CD-O 3.26Å; R85-N141 WeakPolarHBondContact CD-O 3.36Å; R85-N141 WeakPolarHBondContact CG-O 3.44Å; R85-N141 PolarHBondContact NH1-O 2.81Å; R85-T142 VanDerWaalsContact CD-C 3.45Å; R85-L146 HydrophobicContact CB-CD2 4.31Å; R85-D336 PolarHBondContact NH1-O 3.02Å; R85-E359 WeakPolarHBondContact CB-OE1 3.44Å; R85-E359 IonicContact CZ-OE1 2.91Å; R85-E359 IonicContact CZ-OE2 2.73Å; R85-E359 IonicContact NE-OE1 3.83Å; R85-E359 PolarHBondContact NE-OE1 2.57Å; R85-E359 IonicContact NE-OE2 3.65Å; R85-E359 IonicContact NH2-OE1 2.99Å; R85-E359 PolarHBondContact NH2-OE1 3.16Å; R85-E359 IonicContact NH2-OE2 3.77Å; R85-E359 PolarHBondContact NH2-OE2 2.9Å; R85-L425 HydrophobicContact CB-CD1 3.99Å; R85-L425 WeakPolarHBondContact O-CD1 3.38Å
86G95.2Very high97.8Very high12 Ų1220 Ų2012%0.12412%0.119CC..THydrogen-bonded Turntrans82.715.7178.100000114.4L140G86-L140 WeakPolarHBondContact CA-O 3.42Å; G86-L140 PolarHBondContact N-O 3.2Å
87I97.4Very high97.9Very high1 Ų119 Ų191%0.00512%0.115CC..EExtended strand (participates in β ladder)trans-73.9143.5175-65.7-67.9000110.1T84 L96 K98 L140 M422T84-I87 WeakPolarHBondContact O-CG1 3.2Å; I87-L96 HydrophobicContact CG2-CB 3.84Å; I87-L96 HydrophobicContact CG2-CD2 3.99Å; I87-L96 HydrophobicContact CG2-CG 4.42Å; I87-K98 HydrophobicContact CD1-CB 3.86Å; I87-K98 HydrophobicContact CD1-CG 4.22Å; I87-L140 WeakPolarHBondContact O-CB 3.4Å; I87-L140 PolarHBondContact O-N 3.48Å; I87-M422 HydrophobicContact CD1-CB 4.36Å; I87-M422 HydrophobicContact CD1-CE 3.99Å; I87-M422 HydrophobicContact CD1-CG 4.34Å; I87-M422 HydrophobicContact CD1-SD 4.07Å; I87-M422 HydrophobicContact CG1-CE 4.38Å; I87-M422 HydrophobicContact CG2-CE 4.25Å
88V98.3Very high97.9Very high0 Ų014.8 Ų14.80%09%0.088CC..EExtended strand (participates in β ladder)trans-102121.6176.2-176.10000109.3L97 V99 I129 F137 Y138 M139V88-L97 HydrophobicContact CB-CB 4.27Å; V88-L97 PolarHBondContact N-O 2.95Å; V88-L97 WeakPolarHBondContact O-CB 3.3Å; V88-L97 PolarHBondContact O-N 3.17Å; V88-V99 HydrophobicContact CG2-CG2 3.78Å; V88-I129 HydrophobicContact CB-CD1 4.34Å; V88-I129 HydrophobicContact CG1-CD1 3.81Å; V88-F137 HydrophobicContact CG1-CB 3.74Å; V88-F137 HydrophobicContact CG1-CD1 3.98Å; V88-F137 HydrophobicContact CG1-CG 4.2Å; V88-Y138 CarbonylContact C-O 3.44Å; V88-Y138 WeakPolarHBondContact CA-O 3.23Å; V88-M139 HydrophobicContact CG2-CG 4.29Å
89L98.3Very high97.9Very high1 Ų114 Ų141%0.0059%0.085CC..EExtended strand (participates in β ladder)trans-91.1127.2174.8-176.3151.1000110.2K91 L96 F137 Y138 L140 Y152 F185L89-K91 HydrophobicContact CD2-CB 4.43Å; L89-K91 HydrophobicContact CD2-CG 3.65Å; L89-L96 HydrophobicContact CB-CD2 4.11Å; L89-L96 HydrophobicContact CD1-CD2 4.01Å; L89-L96 HydrophobicContact CG-CD2 4.17Å; L89-F137 WeakPolarHBondContact O-CA 3.4Å; L89-Y138 PolarHBondContact N-O 3.45Å; L89-Y138 PolarHBondContact O-N 2.94Å; L89-L140 HydrophobicContact CB-CD1 4.16Å; L89-Y152 HydrophobicContact CD1-CD1 3.43Å; L89-Y152 VanDerWaalsContact CD1-CD1 3.43Å; L89-Y152 HydrophobicContact CD1-CD2 3.88Å; L89-Y152 HydrophobicContact CD1-CE1 3.54Å; L89-Y152 HydrophobicContact CD1-CE2 3.99Å; L89-Y152 HydrophobicContact CD1-CG 3.58Å; L89-Y152 HydrophobicContact CD2-CE1 4.43Å; L89-Y152 HydrophobicContact CG-CD1 4.23Å; L89-Y152 HydrophobicContact CG-CE1 3.9Å; L89-F185 HydrophobicContact CD1-CD2 3.29Å; L89-F185 HydrophobicContact CD1-CE2 3.52Å; L89-F185 HydrophobicContact CD1-CG 4.01Å; L89-F185 HydrophobicContact CD1-CZ 4.37Å; L89-F185 HydrophobicContact CD2-CB 4.1Å; L89-F185 HydrophobicContact CD2-CD1 3.99Å; L89-F185 HydrophobicContact CD2-CD2 3.83Å; L89-F185 HydrophobicContact CD2-CE1 4.39Å; L89-F185 HydrophobicContact CD2-CE2 4.27Å; L89-F185 HydrophobicContact CD2-CG 3.67Å; L89-F185 HydrophobicContact CG-CD2 4.2Å; L89-F185 HydrophobicContact CG-CE2 4.42Å
90D98.4Very high97.8Very high0 Ų012.1 Ų12.10%08%0.076CC..EExtended strand (participates in β ladder)trans-90104.3171.1-174.1-14.5000110.4T92 L93 G94 N95 L97 Y124 R136 F137D90-T92 PolarHBondContact O-N 2.9Å; D90-T92 VanDerWaalsContact O-N 3.14Å; D90-T92 WeakPolarHBondContact OD1-CA 3.36Å; D90-T92 VanDerWaalsContact OD1-CB 3.27Å; D90-T92 WeakPolarHBondContact OD1-CB 3.15Å; D90-T92 PolarHBondContact OD1-N 2.86Å; D90-L93 PolarHBondContact O-N 2.91Å; D90-L93 PolarHBondContact OD1-N 3.1Å; D90-G94 PolarHBondContact O-N 2.86Å; D90-N95 PolarHBondContact N-O 2.96Å; D90-L97 HydrophobicContact CB-CD1 4.38Å; D90-Y124 WeakPolarHBondContact OD2-CE1 3.46Å; D90-Y124 PolarHBondContact OD2-OH 2.91Å; D90-R136 WeakPolarHBondContact OD1-CG 3.43Å; D90-R136 IonicContact OD1-CZ 3Å; D90-R136 IonicContact OD1-NE 3.69Å; D90-R136 PolarHBondContact OD1-NE 2.94Å; D90-R136 IonicContact OD1-NH2 3.27Å; D90-R136 IonicContact OD2-CZ 3.06Å; D90-R136 IonicContact OD2-NE 3.41Å; D90-R136 PolarHBondContact OD2-NE 3.02Å; D90-R136 IonicContact OD2-NH2 2.74Å; D90-R136 PolarHBondContact OD2-NH2 2.99Å; D90-F137 HydrophobicContact CB-CD1 4.09Å; D90-F137 HydrophobicContact CB-CE1 3.86Å
91K98.3Very high97.8Very high26 Ų2610.7 Ų10.711%0.1137%0.067CC..THydrogen-bonded Turntrans-64.7-15.5179.2-67.9176.9-86179.70113.1L89 T134 D135 R136 Y181 R182 F185L89-K91 HydrophobicContact CD2-CB 4.43Å; L89-K91 HydrophobicContact CD2-CG 3.65Å; K91-T134 PolarHBondContact NZ-O 2.96Å; K91-D135 WeakPolarHBondContact CE-O 3.29Å; K91-D135 VanDerWaalsContact NZ-C 3.29Å; K91-D135 PolarHBondContact NZ-O 2.86Å; K91-R136 VanDerWaalsContact CB-O 3.25Å; K91-R136 WeakPolarHBondContact CB-O 3.44Å; K91-R136 WeakPolarHBondContact CE-O 3.42Å; K91-R136 WeakPolarHBondContact CG-O 3.37Å; K91-R136 PolarHBondContact N-O 3.22Å; K91-Y181 CarbonylContact O-C 3.58Å; K91-Y181 WeakPolarHBondContact O-CB 3.23Å; K91-R182 HydrophobicContact CB-CB 4.1Å; K91-R182 HydrophobicContact CB-CG 4.29Å; K91-R182 WeakPolarHBondContact O-CA 3.44Å; K91-R182 WeakPolarHBondContact O-CB 3.33Å; K91-R182 PolarHBondContact O-N 3.01Å; K91-F185 HydrophobicContact CD-CD1 3.79Å; K91-F185 HydrophobicContact CD-CE1 4.21Å; K91-F185 HydrophobicContact CG-CD1 3.75Å; K91-F185 HydrophobicContact CG-CE1 4.39Å; K91-F185 HydrophobicContact CG-CG 4.38Å
92T97.8Very high97.7Very high33 Ų3313.7 Ų13.720%0.2028%0.079CC..THydrogen-bonded Turntrans-91.5-39.5-178.5-57.20000112.4D90 R136 K170D90-T92 PolarHBondContact O-N 2.9Å; D90-T92 VanDerWaalsContact O-N 3.14Å; D90-T92 WeakPolarHBondContact OD1-CA 3.36Å; D90-T92 VanDerWaalsContact OD1-CB 3.27Å; D90-T92 WeakPolarHBondContact OD1-CB 3.15Å; D90-T92 PolarHBondContact OD1-N 2.86Å; T92-R136 WeakPolarHBondContact OG1-CG 3.11Å; T92-K170 HydrophobicContact CG2-CD 4.36Å; T92-K170 HydrophobicContact CG2-CG 4.34Å; T92-K170 WeakPolarHBondContact O-CA 3.25Å
93L97.9Very high97.6Very high7 Ų713.7 Ų13.74%0.0378%0.079CC..THydrogen-bonded Turntrans-112.9-3.9-171.4-61176.9000113.9D90 N95 H110 Y123 Y124 R136 R169 Y181D90-L93 PolarHBondContact O-N 2.91Å; D90-L93 PolarHBondContact OD1-N 3.1Å; L93-N95 VanDerWaalsContact C-N 3.28Å; L93-N95 PolarHBondContact O-N 2.88Å; L93-H110 PolarHBondContact O-CE1 3.45Å; L93-Y123 HydrophobicContact CB-CD1 4.41Å; L93-Y123 HydrophobicContact CD1-CD1 4.04Å; L93-Y123 HydrophobicContact CD2-CD1 4.32Å; L93-Y123 HydrophobicContact CG-CD1 4.5Å; L93-Y124 HydrophobicContact CD1-CE1 3.88Å; L93-R136 VanDerWaalsContact CD1-NH2 3.32Å; L93-R169 HydrophobicContact CD2-CG 4.03Å; L93-Y181 WeakPolarHBondContact O-CE2 3.42Å
94G97.9Very high97.6Very high1 Ų116.1 Ų16.11%0.019%0.092CC..  trans75.516.1174.500000114.6D90 Y181D90-G94 PolarHBondContact O-N 2.86Å; G94-Y181 VanDerWaalsContact CA-CD1 3.4Å; G94-Y181 VanDerWaalsContact N-CD2 3.33Å
95N98.6Very high97.6Very high0 Ų016.3 Ų16.30%09%0.092CC..EExtended strand (participates in β ladder)trans-99.5145.7-175.5-63.9-40000111.5D90 L93 L97 S109 H110 Y124D90-N95 PolarHBondContact N-O 2.96Å; L93-N95 VanDerWaalsContact C-N 3.28Å; L93-N95 PolarHBondContact O-N 2.88Å; N95-L97 HydrophobicContact CB-CD2 4.05Å; N95-S109 CarbonylContact C-O 3.57Å; N95-S109 WeakPolarHBondContact CA-O 3.28Å; N95-H110 WeakPolarHBondContact OD1-CB 3.34Å; N95-H110 PolarHBondContact OD1-ND1 3.32Å; N95-Y124 VanDerWaalsContact CB-OH 3.31Å; N95-Y124 WeakPolarHBondContact CB-OH 3.49Å; N95-Y124 PolarHBondContact ND2-OH 3.14Å
96L98.7Very high97.6Very high1 Ų118 Ų181%0.00510%0.101CC..EExtended strand (participates in β ladder)trans-97.4126.1166.7-65.9177.9000109F82 I87 L89 C108 S109 L140 T149 Y152 A153 M422F82-L96 HydrophobicContact CE1-CD1 3.89Å; F82-L96 HydrophobicContact CZ-CD1 4.08Å; I87-L96 HydrophobicContact CG2-CB 3.84Å; I87-L96 HydrophobicContact CG2-CD2 3.99Å; I87-L96 HydrophobicContact CG2-CG 4.42Å; L89-L96 HydrophobicContact CB-CD2 4.11Å; L89-L96 HydrophobicContact CD1-CD2 4.01Å; L89-L96 HydrophobicContact CG-CD2 4.17Å; L96-C108 WeakPolarHBondContact O-CA 3.3Å; L96-S109 PolarHBondContact N-O 3.39Å; L96-S109 PolarHBondContact O-N 3Å; L96-L140 HydrophobicContact CD2-CD1 4.43Å; L96-T149 HydrophobicContact CD1-CG2 4.09Å; L96-Y152 HydrophobicContact CD2-CD1 4.12Å; L96-Y152 HydrophobicContact CG-CD1 4.48Å; L96-A153 HydrophobicContact CD1-CB 3.93Å; L96-M422 HydrophobicContact CB-CE 3.51Å; L96-M422 HydrophobicContact CD1-CE 4.05Å; L96-M422 HydrophobicContact CG-CE 4.45Å
97L98.6Very high97.7Very high0 Ų018.6 Ų18.60%010%0.103CC..EExtended strand (participates in β ladder)trans-121.2129.4-170.9-53.3176.6000110.7V88 D90 N95 V99 I105 V107 C108 Y124 I129 F137V88-L97 HydrophobicContact CB-CB 4.27Å; V88-L97 PolarHBondContact N-O 2.95Å; V88-L97 WeakPolarHBondContact O-CB 3.3Å; V88-L97 PolarHBondContact O-N 3.17Å; D90-L97 HydrophobicContact CB-CD1 4.38Å; N95-L97 HydrophobicContact CB-CD2 4.05Å; L97-V99 HydrophobicContact CB-CG1 4.06Å; L97-I105 HydrophobicContact CD2-CD1 4.39Å; L97-I105 HydrophobicContact CD2-CG2 4.3Å; L97-V107 WeakPolarHBondContact CA-O 3.43Å; L97-C108 HydrophobicContact CD2-CB 3.83Å; L97-C108 WeakPolarHBondContact CD2-SG 3.42Å; L97-Y124 HydrophobicContact CD1-CE1 4.16Å; L97-Y124 HydrophobicContact CD2-CE2 3.88Å; L97-I129 HydrophobicContact CD1-CD1 4.06Å; L97-I129 HydrophobicContact CD1-CG2 3.8Å; L97-F137 HydrophobicContact CD1-CE1 4.22Å
98K98.4Very high97.7Very high6 Ų618.7 Ų18.73%0.02610%0.103CC..EExtended strand (participates in β ladder)trans-97.2127.1161.9-166.2176.6-176.5179.10107.8I87 L106 V107 M422 S424 R427 T433I87-K98 HydrophobicContact CD1-CB 3.86Å; I87-K98 HydrophobicContact CD1-CG 4.22Å; K98-L106 WeakPolarHBondContact O-CB 3.48Å; K98-L106 PolarHBondContact O-N 2.93Å; K98-V107 HydrophobicContact CB-CB 3.77Å; K98-V107 HydrophobicContact CB-CG2 4.21Å; K98-V107 HydrophobicContact CD-CB 4.4Å; K98-V107 HydrophobicContact CD-CG2 4.01Å; K98-V107 PolarHBondContact N-O 3.44Å; K98-V107 PolarHBondContact O-N 3.28Å; K98-M422 WeakPolarHBondContact CD-O 3.4Å; K98-M422 PolarHBondContact NZ-O 2.92Å; K98-S424 WeakPolarHBondContact CE-O 3.26Å; K98-S424 PolarHBondContact NZ-O 3.49Å; K98-R427 PolarHBondContact NZ-O 3.43Å; K98-T433 HydrophobicContact CD-CG2 4.29Å; K98-T433 HydrophobicContact CG-CG2 4.1Å
99V98.1Very high97.7Very high3 Ų318.7 Ų18.72%0.01810%0.103CC..EExtended strand (participates in β ladder)trans-130.5156.6-173.1-58.40000112.3V88 L97 N104 I105 I129 T433 L434V88-V99 HydrophobicContact CG2-CG2 3.78Å; L97-V99 HydrophobicContact CB-CG1 4.06Å; V99-N104 CarbonylContact C-O 3.59Å; V99-N104 WeakPolarHBondContact CA-O 3.29Å; V99-N104 WeakPolarHBondContact CB-O 3.27Å; V99-I105 HydrophobicContact CG1-CG1 4.42Å; V99-I129 HydrophobicContact CG1-CD1 3.79Å; V99-I129 HydrophobicContact CG1-CG1 4.1Å; V99-T433 CarbonylContact O-C 3.46Å; V99-T433 WeakPolarHBondContact O-CA 3.44Å; V99-L434 HydrophobicContact CG2-CB 4.16Å; V99-L434 HydrophobicContact CG2-CD2 4.22Å; V99-L434 PolarHBondContact O-N 3.04Å
100D97.6Very high97.7Very high14 Ų1419.8 Ų19.88%0.07511%0.108CC..  trans-82.4-176.7169.676.65.2000112.3N102 G103 N104 L106 T431 Q432D100-N102 PolarHBondContact O-N 3.2Å; D100-N102 WeakPolarHBondContact OD1-CA 3.46Å; D100-N102 WeakPolarHBondContact OD1-CB 3.3Å; D100-N102 PolarHBondContact OD1-N 2.7Å; D100-G103 PolarHBondContact O-N 2.99Å; D100-G103 PolarHBondContact OD1-N 3.18Å; D100-N104 PolarHBondContact N-O 3.32Å; D100-N104 PolarHBondContact OD1-N 3.26Å; D100-N104 WeakPolarHBondContact OD2-CB 3.35Å; D100-N104 PolarHBondContact OD2-ND2 2.98Å; D100-L106 HydrophobicContact CB-CD1 4.33Å; D100-L106 HydrophobicContact CB-CD2 4.32Å; D100-T431 HydrophobicContact CB-CG2 4.08Å; D100-Q432 WeakPolarHBondContact CB-O 3.46Å
101S95.4Very high97.7Very high34 Ų3419.8 Ų19.824%0.23811%0.109CC..THydrogen-bonded Turntrans-65.2-24.1179.758.70000114.6R131 S437S101-R131 PolarHBondContact O-NE 3.39Å; S101-R131 PolarHBondContact O-NH2 2.69Å; S101-R131 VanDerWaalsContact O-NH2 3.13Å; S101-S437 WeakPolarHBondContact CB-OG 3.49Å
102N95.4Very high97.7Very high110 Ų11021.3 Ų21.359%0.58812%0.115SC*.THydrogen-bonded Turntrans-88.3-17.3179.8-63.8-38.6000111.7D100 F128D100-N102 PolarHBondContact O-N 3.2Å; D100-N102 WeakPolarHBondContact OD1-CA 3.46Å; D100-N102 WeakPolarHBondContact OD1-CB 3.3Å; D100-N102 PolarHBondContact OD1-N 2.7Å; N102-F128 WeakPolarHBondContact O-CE2 3.44Å
103G96.4Very high97.6Very high0 Ų026.9 Ų26.90%013%0.133CC..  trans98.411.2-176.600000113.3D100 F128 I129D100-G103 PolarHBondContact O-N 2.99Å; D100-G103 PolarHBondContact OD1-N 3.18Å; G103-F128 CarbonylContact O-C 3.6Å; G103-F128 WeakPolarHBondContact O-CA 3.34Å; G103-I129 PolarHBondContact O-N 2.78Å
104N97.7Very high97.6Very high64 Ų6430 Ų3034%0.34215%0.146SC..BIsolated β-bridgetrans-71.3139172.1-55.8-49.9000109.8V99 D100 K127V99-N104 CarbonylContact C-O 3.59Å; V99-N104 WeakPolarHBondContact CA-O 3.29Å; V99-N104 WeakPolarHBondContact CB-O 3.27Å; D100-N104 PolarHBondContact N-O 3.32Å; D100-N104 PolarHBondContact OD1-N 3.26Å; D100-N104 WeakPolarHBondContact OD2-CB 3.35Å; D100-N104 PolarHBondContact OD2-ND2 2.98Å; N104-K127 WeakPolarHBondContact CA-O 3.35Å
105I98Very high97.5Very high22 Ų2230.9 Ų30.911%0.11315%0.15CC..EExtended strand (participates in β ladder)trans-81.5119.9-177.7-60171.5000109.1L97 V99 C108 V120 Y124 K127 I129L97-I105 HydrophobicContact CD2-CD1 4.39Å; L97-I105 HydrophobicContact CD2-CG2 4.3Å; V99-I105 HydrophobicContact CG1-CG1 4.42Å; I105-C108 HydrophobicContact CG2-CB 4Å; I105-V120 HydrophobicContact CB-CG1 4.45Å; I105-V120 HydrophobicContact CD1-CG1 4.1Å; I105-V120 HydrophobicContact CG2-CG1 4.16Å; I105-Y124 HydrophobicContact CD1-CD1 3.86Å; I105-Y124 HydrophobicContact CD1-CD2 3.38Å; I105-Y124 HydrophobicContact CD1-CE1 4.35Å; I105-Y124 HydrophobicContact CD1-CE2 3.9Å; I105-Y124 HydrophobicContact CD1-CG 3.35Å; I105-K127 PolarHBondContact N-O 2.91Å; I105-I129 HydrophobicContact CD1-CG2 4.17Å; I105-I129 HydrophobicContact CG1-CG2 4.37Å
106L97.1Very high97.3Very high43 Ų4340.3 Ų40.323%0.22519%0.186CC..EExtended strand (participates in β ladder)trans-93.6-44.7176.2-53.1-179.3000111.1K98 D100 T431 T433K98-L106 WeakPolarHBondContact O-CB 3.48Å; K98-L106 PolarHBondContact O-N 2.93Å; D100-L106 HydrophobicContact CB-CD1 4.33Å; D100-L106 HydrophobicContact CB-CD2 4.32Å; L106-T431 HydrophobicContact CD1-CG2 4.29Å; L106-T431 HydrophobicContact CD2-CG2 3.63Å; L106-T433 HydrophobicContact CD1-CG2 4.35Å
107V97.4Very high96.8Very high25 Ų2544.8 Ų44.815%0.15221%0.207CC..EExtended strand (participates in β ladder)trans-137.7139.3178.3-176.20000108.4L97 K98 F114 M422L97-V107 WeakPolarHBondContact CA-O 3.43Å; K98-V107 HydrophobicContact CB-CB 3.77Å; K98-V107 HydrophobicContact CB-CG2 4.21Å; K98-V107 HydrophobicContact CD-CB 4.4Å; K98-V107 HydrophobicContact CD-CG2 4.01Å; K98-V107 PolarHBondContact N-O 3.44Å; K98-V107 PolarHBondContact O-N 3.28Å; V107-F114 HydrophobicContact CG1-CD1 3.7Å; V107-F114 HydrophobicContact CG1-CE1 3.76Å; V107-M422 HydrophobicContact CG1-SD 4.1Å
108C98.1Very high96.4Very high3 Ų352.6 Ų52.62%0.0224%0.243CC..EExtended strand (participates in β ladder)trans-133.6126.6175.1-177.30000109.6L96 L97 I105 L115 V120L96-C108 WeakPolarHBondContact O-CA 3.3Å; L97-C108 HydrophobicContact CD2-CB 3.83Å; L97-C108 WeakPolarHBondContact CD2-SG 3.42Å; I105-C108 HydrophobicContact CG2-CB 4Å; C108-L115 HydrophobicContact CB-CB 4.31Å; C108-L115 PolarHBondContact O-N 3.38Å; C108-V120 HydrophobicContact CB-CG2 3.68Å
109S98.2Very high96.2Very high0 Ų054.5 Ų54.50%025%0.254CS..EExtended strand (participates in β ladder)trans-121.8136.6173.7-166.70000111.3N95 L96 G111 R113N95-S109 CarbonylContact C-O 3.57Å; N95-S109 WeakPolarHBondContact CA-O 3.28Å; L96-S109 PolarHBondContact N-O 3.39Å; L96-S109 PolarHBondContact O-N 3Å; S109-G111 PolarHBondContact OG-O 2.77Å; S109-R113 WeakPolarHBondContact CA-O 3.35Å; S109-R113 PolarHBondContact OG-O 2.96Å
110H98.1Very high96Very high23 Ų2355 Ų5511%0.10626%0.257CS..EExtended strand (participates in β ladder)trans-109.6100.9168.4-165.783.1000108.7L93 N95 F112 R113 L115 V156 Y181L93-H110 PolarHBondContact O-CE1 3.45Å; N95-H110 WeakPolarHBondContact OD1-CB 3.34Å; N95-H110 PolarHBondContact OD1-ND1 3.32Å; H110-F112 PolarHBondContact O-N 3Å; H110-R113 PolarHBondContact N-O 3.45Å; H110-R113 PolarHBondContact O-N 3.5Å; H110-L115 HydrophobicContact CB-CD2 4.22Å; H110-L115 HydrophobicContact CB-CG 4.5Å; H110-V156 WeakPolarHBondContact NE2-CG1 3.47Å; H110-Y181 AromaticContact CE1-CZ 3.6Å; H110-Y181 PolarHBondContact CE1-OH 3Å; H110-Y181 PolarHBondContact NE2-OH 3.13Å
111G97.6Very high95.8Very high1 Ų158.9 Ų58.91%0.0128%0.275CS..THydrogen-bonded Turntrans61.9-123.4-163.200000109.8S109 A153 V156S109-G111 PolarHBondContact OG-O 2.77Å; G111-A153 WeakPolarHBondContact CA-O 3.36Å; G111-V156 VanDerWaalsContact N-CG1 3.29Å
112F97.9Very high95.6Very high57 Ų5764.6 Ų64.625%0.2529%0.292CS..THydrogen-bonded Turntrans-95.82.3173.7-57.6-50.9000114.2Y76 F82 H110 F114 Y150 A153 C154 D157Y76-F112 HydrophobicContact CE1-CE2 4.05Å; F82-F112 AromaticContact CD2-CD1 3.8Å; F82-F112 HydrophobicContact CD2-CD1 3.8Å; F82-F112 HydrophobicContact CD2-CE1 4.11Å; F82-F112 AromaticContact CE2-CD1 3.62Å; F82-F112 HydrophobicContact CE2-CD1 3.62Å; F82-F112 HydrophobicContact CE2-CE1 4.16Å; F82-F112 HydrophobicContact CG-CD1 4.44Å; F82-F112 HydrophobicContact CG-CE1 4.29Å; F82-F112 HydrophobicContact CZ-CD1 4.08Å; F82-F112 HydrophobicContact CZ-CE1 4.36Å; H110-F112 PolarHBondContact O-N 3Å; F112-F114 PolarHBondContact O-N 2.69Å; F112-Y150 HydrophobicContact CE1-CD2 4.11Å; F112-Y150 AromaticContact CE1-CE2 3.64Å; F112-Y150 HydrophobicContact CE1-CE2 3.64Å; F112-Y150 HydrophobicContact CZ-CD2 4.46Å; F112-Y150 AromaticContact CZ-CE2 3.77Å; F112-Y150 HydrophobicContact CZ-CE2 3.77Å; F112-A153 HydrophobicContact CD1-CB 4.17Å; F112-A153 HydrophobicContact CE1-CB 3.74Å; F112-A153 HydrophobicContact CZ-CB 4.4Å; F112-C154 HydrophobicContact CZ-CB 4.36Å; F112-C154 VanDerWaalsContact CZ-SG 3.59Å; F112-D157 HydrophobicContact CD2-CB 3.61Å; F112-D157 WeakPolarHBondContact CD2-OD2 3.21Å; F112-D157 HydrophobicContact CE2-CB 3.95Å; F112-D157 HydrophobicContact CG-CB 4.3Å
113R97.6Very high95.5Very high151 Ų15162.2 Ų62.257%0.5728%0.275SS*.EExtended strand (participates in β ladder)trans-87.5107.7175.3-178.1-176.6164.6-176.6-7.2110S109 H110 L115 D119S109-R113 WeakPolarHBondContact CA-O 3.35Å; S109-R113 PolarHBondContact OG-O 2.96Å; H110-R113 PolarHBondContact N-O 3.45Å; H110-R113 PolarHBondContact O-N 3.5Å; R113-L115 HydrophobicContact CG-CD2 4.29Å; R113-L115 PolarHBondContact O-N 3.06Å; R113-D119 IonicContact CZ-OD2 3.73Å; R113-D119 IonicContact NH2-OD1 2.87Å; R113-D119 IonicContact NH2-OD2 2.69Å; R113-D119 PolarHBondContact NH2-OD2 3.33Å
114F97.4Very high95.5Very high71 Ų7162.7 Ų62.731%0.31128%0.277SS..EExtended strand (participates in β ladder)trans-67.8124.8166.8-69.1-90.4000110.3F82 V107 F112 Q421 M422F82-F114 HydrophobicContact CD2-CZ 4.49Å; F82-F114 HydrophobicContact CE2-CE2 4.28Å; F82-F114 HydrophobicContact CE2-CZ 4.05Å; V107-F114 HydrophobicContact CG1-CD1 3.7Å; V107-F114 HydrophobicContact CG1-CE1 3.76Å; F112-F114 PolarHBondContact O-N 2.69Å; F114-Q421 VanDerWaalsContact CE1-O 3.3Å; F114-Q421 WeakPolarHBondContact CE1-O 3.38Å; F114-Q421 HydrophobicContact CE2-CB 4.07Å; F114-Q421 HydrophobicContact CZ-CB 3.73Å; F114-Q421 VanDerWaalsContact CZ-O 3.27Å; F114-Q421 WeakPolarHBondContact CZ-O 3.43Å; F114-M422 HydrophobicContact CE1-SD 3.84Å; F114-M422 HydrophobicContact CZ-SD 4.33Å
115L96.4Very high95.2Very high21 Ų2170 Ų7011%0.1130%0.3CS..PPolyproline II helixtrans-83137.1-177.8-60.7-168000110.3C108 H110 R113 D119 V120 Y123C108-L115 HydrophobicContact CB-CB 4.31Å; C108-L115 PolarHBondContact O-N 3.38Å; H110-L115 HydrophobicContact CB-CD2 4.22Å; H110-L115 HydrophobicContact CB-CG 4.5Å; R113-L115 HydrophobicContact CG-CD2 4.29Å; R113-L115 PolarHBondContact O-N 3.06Å; L115-D119 HydrophobicContact CB-CB 3.88Å; L115-D119 HydrophobicContact CD1-CB 4.43Å; L115-D119 HydrophobicContact CD2-CB 4.23Å; L115-D119 HydrophobicContact CG-CB 4.41Å; L115-V120 HydrophobicContact CB-CG2 3.79Å; L115-Y123 HydrophobicContact CD1-CD2 3.55Å; L115-Y123 HydrophobicContact CD1-CE2 3.63Å
116R93.3Very high94.9Very high198 Ų19875.1 Ų75.175%0.74733%0.327SS*.PPolyproline II helixtrans-77.2167.3172.2-57.5-176-157.3171.26.2110E118 D119 V120R116-E118 VanDerWaalsContact C-N 3.28Å; R116-E118 PolarHBondContact O-N 3.33Å; R116-D119 WeakPolarHBondContact O-CB 3.14Å; R116-D119 PolarHBondContact O-N 3.26Å; R116-V120 WeakPolarHBondContact O-CG2 3.25Å; R116-V120 PolarHBondContact O-N 3.16Å
117E88.8Confident94.8Very high94 Ų9475.7 Ų75.744%0.43933%0.328SS..Hα-helixtrans-52.5-43-177.9-171.2171.6178.900113.9V120 E121 K127 K409E117-V120 PolarHBondContact O-N 2.76Å; E117-E121 PolarHBondContact O-N 2.97Å; E117-K127 HydrophobicContact CG-CD 4.34Å; E117-K127 VanDerWaalsContact CG-CE 3.45Å; E117-K127 IonicContact OE1-NZ 3.29Å; E117-K127 PolarHBondContact OE1-NZ 3.25Å; E117-K409 IonicContact OE2-NZ 3.33Å; E117-K409 PolarHBondContact OE2-NZ 3.43Å
118E90.4Very high94.8Very high164 Ų16478.6 Ų78.677%0.76634%0.339SS*.Hα-helixtrans-64.7-42.3176.7-63.5167.2-161.700112.3R116 V120 E121 Y122R116-E118 VanDerWaalsContact C-N 3.28Å; R116-E118 PolarHBondContact O-N 3.33Å; E118-V120 VanDerWaalsContact C-N 3.35Å; E118-E121 PolarHBondContact O-N 3.07Å; E118-Y122 PolarHBondContact O-N 3.38Å; E118-Y122 VanDerWaalsContact O-N 3.15Å
119D93.3Very high94.7Very high47 Ų4778.6 Ų78.625%0.25134%0.339SS..Hα-helixtrans-64.7-41.2175.9-70.3-36.4000110.4R113 L115 R116 E121 Y122 Y123R113-D119 IonicContact CZ-OD2 3.73Å; R113-D119 IonicContact NH2-OD1 2.87Å; R113-D119 IonicContact NH2-OD2 2.69Å; R113-D119 PolarHBondContact NH2-OD2 3.33Å; L115-D119 HydrophobicContact CB-CB 3.88Å; L115-D119 HydrophobicContact CD1-CB 4.43Å; L115-D119 HydrophobicContact CD2-CB 4.23Å; L115-D119 HydrophobicContact CG-CB 4.41Å; R116-D119 WeakPolarHBondContact O-CB 3.14Å; R116-D119 PolarHBondContact O-N 3.26Å; D119-E121 VanDerWaalsContact C-N 3.34Å; D119-E121 PolarHBondContact O-N 2.91Å; D119-Y122 WeakPolarHBondContact O-CB 3.47Å; D119-Y122 PolarHBondContact O-N 3.35Å; D119-Y123 WeakPolarHBondContact O-CD2 3.34Å; D119-Y123 PolarHBondContact O-N 2.77Å
120V94.2Very high94.6Very high12 Ų1285.1 Ų85.17%0.07337%0.369CS..Hα-helixtrans-63.1-42.4177.3174.90000110.5I105 C108 L115 R116 E117 E118 Y122 Y123 Y124 K127I105-V120 HydrophobicContact CB-CG1 4.45Å; I105-V120 HydrophobicContact CD1-CG1 4.1Å; I105-V120 HydrophobicContact CG2-CG1 4.16Å; C108-V120 HydrophobicContact CB-CG2 3.68Å; L115-V120 HydrophobicContact CB-CG2 3.79Å; R116-V120 WeakPolarHBondContact O-CG2 3.25Å; R116-V120 PolarHBondContact O-N 3.16Å; E117-V120 PolarHBondContact O-N 2.76Å; E118-V120 VanDerWaalsContact C-N 3.35Å; V120-Y122 VanDerWaalsContact C-N 3.28Å; V120-Y122 PolarHBondContact O-N 2.75Å; V120-Y123 PolarHBondContact O-N 3.08Å; V120-Y123 VanDerWaalsContact O-N 3.14Å; V120-Y124 HydrophobicContact CG1-CD2 4.04Å; V120-Y124 WeakPolarHBondContact O-CA 3.38Å; V120-Y124 WeakPolarHBondContact O-CD2 3.17Å; V120-Y124 PolarHBondContact O-N 3.28Å; V120-K127 HydrophobicContact CG1-CG 4.19Å
121E92.9Very high94.2Very high97 Ų9787.3 Ų87.345%0.45338%0.376SS..Hα-helixtrans-64.6-33.5179.6-162.8164.3159.400112.5E117 E118 D119 Y124 R125 K127E117-E121 PolarHBondContact O-N 2.97Å; E118-E121 PolarHBondContact O-N 3.07Å; D119-E121 VanDerWaalsContact C-N 3.34Å; D119-E121 PolarHBondContact O-N 2.91Å; E121-Y124 CarbonylContact O-C 3.58Å; E121-R125 WeakPolarHBondContact O-CA 3.45Å; E121-R125 PolarHBondContact O-N 3.3Å; E121-K127 VanDerWaalsContact OE2-CE 3.32Å; E121-K127 WeakPolarHBondContact OE2-CE 3.29Å; E121-K127 IonicContact OE2-NZ 2.74Å; E121-K127 PolarHBondContact OE2-NZ 2.88Å
122Y92.1Very high94Very high154 Ų15493.3 Ų93.360%0.60441%0.408SS*.Hα-helixtrans-61.7-41.8171.6174.3-97.8000112.8E118 D119 V120E118-Y122 PolarHBondContact O-N 3.38Å; E118-Y122 VanDerWaalsContact O-N 3.15Å; D119-Y122 WeakPolarHBondContact O-CB 3.47Å; D119-Y122 PolarHBondContact O-N 3.35Å; V120-Y122 VanDerWaalsContact C-N 3.28Å; V120-Y122 PolarHBondContact O-N 2.75Å
123Y92.8Very high93.9Very high59 Ų5993.3 Ų93.323%0.23141%0.411CS..Hα-helixtrans-79-36.8176.9-74-73.8000112.9L93 L115 D119 V120L93-Y123 HydrophobicContact CB-CD1 4.41Å; L93-Y123 HydrophobicContact CD1-CD1 4.04Å; L93-Y123 HydrophobicContact CD2-CD1 4.32Å; L93-Y123 HydrophobicContact CG-CD1 4.5Å; L115-Y123 HydrophobicContact CD1-CD2 3.55Å; L115-Y123 HydrophobicContact CD1-CE2 3.63Å; D119-Y123 WeakPolarHBondContact O-CD2 3.34Å; D119-Y123 PolarHBondContact O-N 2.77Å; V120-Y123 PolarHBondContact O-N 3.08Å; V120-Y123 VanDerWaalsContact O-N 3.14Å
124Y96.3Very high93.7Very high11 Ų1191.1 Ų91.14%0.04342%0.415CS..  trans-13688.4-171-49.9-81.8000109.4D90 L93 N95 L97 I105 V120 E121 N126 K127 I129D90-Y124 WeakPolarHBondContact OD2-CE1 3.46Å; D90-Y124 PolarHBondContact OD2-OH 2.91Å; L93-Y124 HydrophobicContact CD1-CE1 3.88Å; N95-Y124 VanDerWaalsContact CB-OH 3.31Å; N95-Y124 WeakPolarHBondContact CB-OH 3.49Å; N95-Y124 PolarHBondContact ND2-OH 3.14Å; L97-Y124 HydrophobicContact CD1-CE1 4.16Å; L97-Y124 HydrophobicContact CD2-CE2 3.88Å; I105-Y124 HydrophobicContact CD1-CD1 3.86Å; I105-Y124 HydrophobicContact CD1-CD2 3.38Å; I105-Y124 HydrophobicContact CD1-CE1 4.35Å; I105-Y124 HydrophobicContact CD1-CE2 3.9Å; I105-Y124 HydrophobicContact CD1-CG 3.35Å; V120-Y124 HydrophobicContact CG1-CD2 4.04Å; V120-Y124 WeakPolarHBondContact O-CA 3.38Å; V120-Y124 WeakPolarHBondContact O-CD2 3.17Å; V120-Y124 PolarHBondContact O-N 3.28Å; E121-Y124 CarbonylContact O-C 3.58Å; Y124-N126 PolarHBondContact O-N 3.1Å; Y124-K127 WeakPolarHBondContact O-CA 3.29Å; Y124-K127 PolarHBondContact O-N 2.88Å; Y124-I129 HydrophobicContact CD1-CG2 4Å; Y124-I129 HydrophobicContact CE1-CG2 4.03Å
125R90.4Very high93.6Very high217 Ų21792.4 Ų92.482%0.81942%0.424SS*.THydrogen-bonded Turntrans-50.9-33.3-172.8-169.6173.1-176.6172.60.9115.1E121E121-R125 WeakPolarHBondContact O-CA 3.45Å; E121-R125 PolarHBondContact O-N 3.3Å
126N92.6Very high93.6Very high130 Ų13094.4 Ų94.470%0.69543%0.431SS*.THydrogen-bonded Turntrans-105.113.7178.9-69.23.1000113.2Y124 F128Y124-N126 PolarHBondContact O-N 3.1Å; N126-F128 HydrophobicContact CB-CB 4.15Å; N126-F128 WeakPolarHBondContact O-CB 3.29Å; N126-F128 PolarHBondContact O-N 3.36Å
127K95.1Very high93.9Very high55 Ų5585.4 Ų85.424%0.23940%0.397CS..SBendtrans48.336.5-173.5-62.2172.2-176.7151.70112.4N104 I105 E117 V120 E121 Y124N104-K127 WeakPolarHBondContact CA-O 3.35Å; I105-K127 PolarHBondContact N-O 2.91Å; E117-K127 HydrophobicContact CG-CD 4.34Å; E117-K127 VanDerWaalsContact CG-CE 3.45Å; E117-K127 IonicContact OE1-NZ 3.29Å; E117-K127 PolarHBondContact OE1-NZ 3.25Å; V120-K127 HydrophobicContact CG1-CG 4.19Å; E121-K127 VanDerWaalsContact OE2-CE 3.32Å; E121-K127 WeakPolarHBondContact OE2-CE 3.29Å; E121-K127 IonicContact OE2-NZ 2.74Å; E121-K127 PolarHBondContact OE2-NZ 2.88Å; Y124-K127 WeakPolarHBondContact O-CA 3.29Å; Y124-K127 PolarHBondContact O-N 2.88Å
128F97.1Very high94.3Very high85 Ų8584.5 Ų84.537%0.37339%0.39SS..BIsolated β-bridgetrans-140.8146.6-167.2168-89.7000110.9N102 G103 N126 Q130N102-F128 WeakPolarHBondContact O-CE2 3.44Å; G103-F128 CarbonylContact O-C 3.6Å; G103-F128 WeakPolarHBondContact O-CA 3.34Å; N126-F128 HydrophobicContact CB-CB 4.15Å; N126-F128 WeakPolarHBondContact O-CB 3.29Å; N126-F128 PolarHBondContact O-N 3.36Å; F128-Q130 HydrophobicContact CE1-CG 3.67Å; F128-Q130 HydrophobicContact CZ-CG 4.27Å
129I97.3Very high94.5Very high4 Ų478.8 Ų78.82%0.02136%0.364CS..  trans-126.1145.2171.464.8167000112.2V88 L97 V99 G103 I105 Y124 R131 F137V88-I129 HydrophobicContact CB-CD1 4.34Å; V88-I129 HydrophobicContact CG1-CD1 3.81Å; L97-I129 HydrophobicContact CD1-CD1 4.06Å; L97-I129 HydrophobicContact CD1-CG2 3.8Å; V99-I129 HydrophobicContact CG1-CD1 3.79Å; V99-I129 HydrophobicContact CG1-CG1 4.1Å; G103-I129 PolarHBondContact O-N 2.78Å; I105-I129 HydrophobicContact CD1-CG2 4.17Å; I105-I129 HydrophobicContact CG1-CG2 4.37Å; Y124-I129 HydrophobicContact CD1-CG2 4Å; Y124-I129 HydrophobicContact CE1-CG2 4.03Å; I129-R131 PolarHBondContact O-N 2.97Å; I129-R131 VanDerWaalsContact O-N 3.12Å; I129-F137 HydrophobicContact CB-CE1 3.96Å; I129-F137 HydrophobicContact CB-CE2 3.95Å; I129-F137 HydrophobicContact CB-CZ 3.61Å; I129-F137 HydrophobicContact CD1-CD1 3.99Å; I129-F137 HydrophobicContact CD1-CE1 4.12Å; I129-F137 HydrophobicContact CD1-CG 4.27Å; I129-F137 HydrophobicContact CG2-CE1 3.7Å; I129-F137 HydrophobicContact CG2-CE2 4.43Å; I129-F137 HydrophobicContact CG2-CZ 3.59Å
130Q95.8Very high94.7Very high137 Ų13776.7 Ų76.764%0.6435%0.353SS*.  trans-82.185.6169.4-67.5-179.4-26.500109.2F128 D132 D133 F137F128-Q130 HydrophobicContact CE1-CG 3.67Å; F128-Q130 HydrophobicContact CZ-CG 4.27Å; Q130-D132 PolarHBondContact O-N 3.37Å; Q130-D133 HydrophobicContact CB-CB 4.49Å; Q130-D133 VanDerWaalsContact O-CB 3.3Å; Q130-D133 WeakPolarHBondContact O-CB 3.43Å; Q130-D133 PolarHBondContact O-N 3.03Å; Q130-F137 WeakPolarHBondContact O-CD2 3.31Å
131R90Very high94.6Very high68 Ų6876.8 Ų76.826%0.25735%0.353SS..THydrogen-bonded Turntrans-60.3-17.5-174.265-179.5175.473.80.6115.6S101 I129 D133 M139S101-R131 PolarHBondContact O-NE 3.39Å; S101-R131 PolarHBondContact O-NH2 2.69Å; S101-R131 VanDerWaalsContact O-NH2 3.13Å; I129-R131 PolarHBondContact O-N 2.97Å; I129-R131 VanDerWaalsContact O-N 3.12Å; R131-D133 VanDerWaalsContact C-N 3.29Å; R131-M139 HydrophobicContact CB-CE 4.09Å; R131-M139 WeakPolarHBondContact O-CE 3.34Å
132D91.5Very high94.6Very high127 Ų12773.1 Ų73.168%0.67934%0.337SS*.THydrogen-bonded Turntrans-80.9-10.9176.2-60.5-30.8000112.4Q130 T134Q130-D132 PolarHBondContact O-N 3.37Å; D132-T134 PolarHBondContact O-N 3.49Å
133D95.6Very high94.7Very high58 Ų5866.1 Ų66.131%0.3131%0.31SS..  trans-74.276.8167.1-179.64.8000110.1Q130 R131 D135 R136 F137Q130-D133 HydrophobicContact CB-CB 4.49Å; Q130-D133 VanDerWaalsContact O-CB 3.3Å; Q130-D133 WeakPolarHBondContact O-CB 3.43Å; Q130-D133 PolarHBondContact O-N 3.03Å; R131-D133 VanDerWaalsContact C-N 3.29Å; D133-D135 PolarHBondContact O-N 2.99Å; D133-D135 PolarHBondContact OD1-N 3.23Å; D133-R136 PolarHBondContact O-N 3.49Å; D133-R136 PolarHBondContact OD1-N 2.92Å; D133-R136 VanDerWaalsContact OD1-N 3.09Å; D133-R136 WeakPolarHBondContact OD2-CB 3.39Å; D133-F137 HydrophobicContact CB-CD2 4.17Å; D133-F137 PolarHBondContact O-N 2.71Å
134T93.8Very high94.7Very high105 Ų10565.6 Ų65.664%0.64431%0.309SS*.THydrogen-bonded Turntrans-69-16.8178.657.10000113.3K91 D132 R136 F137K91-T134 PolarHBondContact NZ-O 2.96Å; D132-T134 PolarHBondContact O-N 3.49Å; T134-R136 VanDerWaalsContact C-N 3.34Å; T134-F137 WeakPolarHBondContact CA-O 3.38Å
135D95.5Very high94.7Very high97 Ų9765.7 Ų65.752%0.51931%0.31SS..THydrogen-bonded Turntrans-68.9-35.9171.3178.363000110.9K91 D133 R182K91-D135 WeakPolarHBondContact CE-O 3.29Å; K91-D135 VanDerWaalsContact NZ-C 3.29Å; K91-D135 PolarHBondContact NZ-O 2.86Å; D133-D135 PolarHBondContact O-N 2.99Å; D133-D135 PolarHBondContact OD1-N 3.23Å; D135-R182 VanDerWaalsContact O-CZ 3.22Å; D135-R182 PolarHBondContact O-NH1 3.47Å; D135-R182 PolarHBondContact O-NH2 3.27Å; D135-R182 IonicContact OD1-CZ 3.1Å; D135-R182 IonicContact OD1-NH1 3.87Å; D135-R182 PolarHBondContact OD1-NH1 2.86Å; D135-R182 IonicContact OD1-NH2 2.72Å; D135-R182 IonicContact OD2-CZ 2.77Å; D135-R182 IonicContact OD2-NH1 2.78Å; D135-R182 PolarHBondContact OD2-NH1 3.32Å; D135-R182 IonicContact OD2-NH2 3.43Å; D135-R182 PolarHBondContact OD2-NH2 2.86Å
136R97.4Very high95.1Very high63 Ų6356 Ų5624%0.23828%0.275CS..THydrogen-bonded Turntrans-92.1-44.2176.4179168.7176.1-172.2-4.8114.1D90 K91 T92 L93 D133 T134D90-R136 WeakPolarHBondContact OD1-CG 3.43Å; D90-R136 IonicContact OD1-CZ 3Å; D90-R136 IonicContact OD1-NE 3.69Å; D90-R136 PolarHBondContact OD1-NE 2.94Å; D90-R136 IonicContact OD1-NH2 3.27Å; D90-R136 IonicContact OD2-CZ 3.06Å; D90-R136 IonicContact OD2-NE 3.41Å; D90-R136 PolarHBondContact OD2-NE 3.02Å; D90-R136 IonicContact OD2-NH2 2.74Å; D90-R136 PolarHBondContact OD2-NH2 2.99Å; K91-R136 VanDerWaalsContact CB-O 3.25Å; K91-R136 WeakPolarHBondContact CB-O 3.44Å; K91-R136 WeakPolarHBondContact CE-O 3.42Å; K91-R136 WeakPolarHBondContact CG-O 3.37Å; K91-R136 PolarHBondContact N-O 3.22Å; T92-R136 WeakPolarHBondContact OG1-CG 3.11Å; L93-R136 VanDerWaalsContact CD1-NH2 3.32Å; D133-R136 PolarHBondContact O-N 3.49Å; D133-R136 PolarHBondContact OD1-N 2.92Å; D133-R136 VanDerWaalsContact OD1-N 3.09Å; D133-R136 WeakPolarHBondContact OD2-CB 3.39Å; T134-R136 VanDerWaalsContact C-N 3.34Å
137F98.1Very high95.3Very high10 Ų1050 Ų504%0.04424%0.243CC..EExtended strand (participates in β ladder)trans-105.6134-170.7-61-71.2000111.3V88 L89 D90 L97 I129 Q130 D133 T134V88-F137 HydrophobicContact CG1-CB 3.74Å; V88-F137 HydrophobicContact CG1-CD1 3.98Å; V88-F137 HydrophobicContact CG1-CG 4.2Å; L89-F137 WeakPolarHBondContact O-CA 3.4Å; D90-F137 HydrophobicContact CB-CD1 4.09Å; D90-F137 HydrophobicContact CB-CE1 3.86Å; L97-F137 HydrophobicContact CD1-CE1 4.22Å; I129-F137 HydrophobicContact CB-CE1 3.96Å; I129-F137 HydrophobicContact CB-CE2 3.95Å; I129-F137 HydrophobicContact CB-CZ 3.61Å; I129-F137 HydrophobicContact CD1-CD1 3.99Å; I129-F137 HydrophobicContact CD1-CE1 4.12Å; I129-F137 HydrophobicContact CD1-CG 4.27Å; I129-F137 HydrophobicContact CG2-CE1 3.7Å; I129-F137 HydrophobicContact CG2-CE2 4.43Å; I129-F137 HydrophobicContact CG2-CZ 3.59Å; Q130-F137 WeakPolarHBondContact O-CD2 3.31Å; D133-F137 HydrophobicContact CB-CD2 4.17Å; D133-F137 PolarHBondContact O-N 2.71Å; T134-F137 WeakPolarHBondContact CA-O 3.38Å
138Y97.4Very high95.4Very high74 Ų7447.6 Ų47.629%0.2923%0.232SC..EExtended strand (participates in β ladder)trans-118.1129.1176.2-170-88.5000110.5V88 L89 L140 F185V88-Y138 CarbonylContact C-O 3.44Å; V88-Y138 WeakPolarHBondContact CA-O 3.23Å; L89-Y138 PolarHBondContact N-O 3.45Å; L89-Y138 PolarHBondContact O-N 2.94Å; Y138-L140 HydrophobicContact CD1-CD2 3.87Å; Y138-L140 HydrophobicContact CD1-CG 4.1Å; Y138-L140 HydrophobicContact CE1-CD2 3.83Å; Y138-L140 HydrophobicContact CE1-CG 4.41Å; Y138-F185 HydrophobicContact CD1-CE1 4.09Å; Y138-F185 HydrophobicContact CD1-CE2 4.46Å; Y138-F185 AromaticContact CD1-CZ 3.47Å; Y138-F185 HydrophobicContact CD1-CZ 3.47Å; Y138-F185 VanDerWaalsContact CD1-CZ 3.47Å; Y138-F185 AromaticContact CD2-CE1 3.98Å; Y138-F185 HydrophobicContact CD2-CE1 3.98Å; Y138-F185 HydrophobicContact CD2-CZ 4.15Å; Y138-F185 AromaticContact CE1-CZ 3.95Å; Y138-F185 HydrophobicContact CE1-CZ 3.95Å; Y138-F185 AromaticContact CG-CE1 3.67Å; Y138-F185 HydrophobicContact CG-CE1 3.67Å; Y138-F185 AromaticContact CG-CZ 3.57Å; Y138-F185 HydrophobicContact CG-CZ 3.57Å
139M95.8Very high95.4Very high45 Ų4543.6 Ų43.622%0.22222%0.215CC..EExtended strand (participates in β ladder)trans-96.6119.5-179.3-56.4-174-163.100110.9V88 R131 N141 L434V88-M139 HydrophobicContact CG2-CG 4.29Å; R131-M139 HydrophobicContact CB-CE 4.09Å; R131-M139 WeakPolarHBondContact O-CE 3.34Å; M139-N141 VanDerWaalsContact CB-ND2 3.35Å; M139-N141 WeakPolarHBondContact CB-ND2 3.35Å; M139-N141 PolarHBondContact O-N 3.08Å; M139-L434 HydrophobicContact CE-CD2 4.23Å; M139-L434 HydrophobicContact SD-CD2 3.95Å
140L95.9Very high95.5Very high2 Ų244.3 Ų44.31%0.0122%0.218CC..EExtended strand (participates in β ladder)trans-90.278.5-178.5-63.7155.4000109.2G86 I87 L89 L96 Y138 N145 T149G86-L140 WeakPolarHBondContact CA-O 3.42Å; G86-L140 PolarHBondContact N-O 3.2Å; I87-L140 WeakPolarHBondContact O-CB 3.4Å; I87-L140 PolarHBondContact O-N 3.48Å; L89-L140 HydrophobicContact CB-CD1 4.16Å; L96-L140 HydrophobicContact CD2-CD1 4.43Å; Y138-L140 HydrophobicContact CD1-CD2 3.87Å; Y138-L140 HydrophobicContact CD1-CG 4.1Å; Y138-L140 HydrophobicContact CE1-CD2 3.83Å; Y138-L140 HydrophobicContact CE1-CG 4.41Å; L140-N145 WeakPolarHBondContact CA-OD1 3.44Å; L140-N145 HydrophobicContact CB-CB 3.8Å; L140-N145 HydrophobicContact CD2-CB 3.76Å; L140-N145 HydrophobicContact CG-CB 4.4Å; L140-T149 HydrophobicContact CD1-CG2 4.28Å; L140-T149 WeakPolarHBondContact CD1-OG1 3.48Å
141N92.3Very high95.6Very high15 Ų1537.9 Ų37.98%0.0819%0.188CC..  trans-95.3-11.8-163.9-77.7-37000115.8R85 M139 N145 I338R85-N141 VanDerWaalsContact CD-O 3.26Å; R85-N141 WeakPolarHBondContact CD-O 3.36Å; R85-N141 WeakPolarHBondContact CG-O 3.44Å; R85-N141 PolarHBondContact NH1-O 2.81Å; M139-N141 VanDerWaalsContact CB-ND2 3.35Å; M139-N141 WeakPolarHBondContact CB-ND2 3.35Å; M139-N141 PolarHBondContact O-N 3.08Å; N141-N145 PolarHBondContact N-OD1 2.84Å; N141-N145 VanDerWaalsContact N-OD1 3.12Å; N141-I338 HydrophobicContact CB-CG2 4.23Å
142T93.4Very high96Very high19 Ų1934.7 Ų34.712%0.11718%0.176CC..SBendtrans-108.8158-178.264.30000111R85 F144 N145 H337R85-T142 VanDerWaalsContact CD-C 3.45Å; T142-F144 PolarHBondContact O-N 2.78Å; T142-N145 PolarHBondContact N-OD1 3.22Å; T142-N145 VanDerWaalsContact N-OD1 3.12Å; T142-N145 WeakPolarHBondContact O-CB 3.46Å; T142-N145 PolarHBondContact O-N 3.22Å; T142-N145 PolarHBondContact OG1-OD1 2.85Å; T142-H337 HydrophobicContact CG2-CB 4.35Å
143L94.9Very high96.4Very high8 Ų828.7 Ų28.74%0.04214%0.144CC..THydrogen-bonded Turntrans-63.9-28.8175.1-75.1169.4000112.3Y42 N145 L146 P358 E359Y42-L143 HydrophobicContact CD1-CB 3.99Å; Y42-L143 HydrophobicContact CD1-CD1 3.31Å; Y42-L143 HydrophobicContact CD1-CG 4.28Å; Y42-L143 HydrophobicContact CD2-CB 3.88Å; Y42-L143 HydrophobicContact CD2-CD1 4.46Å; Y42-L143 HydrophobicContact CE1-CB 3.69Å; Y42-L143 HydrophobicContact CE1-CD1 3.58Å; Y42-L143 HydrophobicContact CE1-CG 4.25Å; Y42-L143 HydrophobicContact CE2-CB 3.58Å; Y42-L143 HydrophobicContact CG-CB 4.06Å; Y42-L143 HydrophobicContact CG-CD1 3.79Å; Y42-L143 VanDerWaalsContact CZ-CB 3.46Å; L143-N145 PolarHBondContact O-N 3.03Å; L143-N145 VanDerWaalsContact O-N 3.14Å; L143-L146 HydrophobicContact CD2-CD1 3.62Å; L143-L146 HydrophobicContact CD2-CG 4.35Å; L143-L146 WeakPolarHBondContact O-CB 3.18Å; L143-L146 WeakPolarHBondContact O-CG 3.26Å; L143-L146 PolarHBondContact O-N 2.92Å; L143-L146 VanDerWaalsContact O-N 3.11Å; L143-P358 HydrophobicContact CD1-CB 4.07Å; L143-P358 HydrophobicContact CD1-CG 3.63Å; L143-E359 HydrophobicContact CD2-CG 4.21Å; L143-E359 WeakPolarHBondContact CD2-OE1 3.26Å
144F92.8Very high96.5Very high48 Ų4826 Ų2621%0.21113%0.129CC..THydrogen-bonded Turntrans-56.4-26.3169.4-66.2-73.7000113.9D41 Y42 Y47 Y52 T142 L146D41-F144 HydrophobicContact CB-CE2 4Å; D41-F144 HydrophobicContact CB-CZ 3.9Å; Y42-F144 AromaticContact CD2-CD2 3.96Å; Y42-F144 HydrophobicContact CD2-CD2 3.96Å; Y42-F144 HydrophobicContact CD2-CE1 4.44Å; Y42-F144 AromaticContact CD2-CE2 3.56Å; Y42-F144 HydrophobicContact CD2-CE2 3.56Å; Y42-F144 AromaticContact CD2-CZ 3.83Å; Y42-F144 HydrophobicContact CD2-CZ 3.83Å; Y42-F144 HydrophobicContact CE2-CD1 4Å; Y42-F144 AromaticContact CE2-CD2 3.87Å; Y42-F144 HydrophobicContact CE2-CD2 3.87Å; Y42-F144 AromaticContact CE2-CE1 3.86Å; Y42-F144 HydrophobicContact CE2-CE1 3.86Å; Y42-F144 AromaticContact CE2-CE2 3.72Å; Y42-F144 HydrophobicContact CE2-CE2 3.72Å; Y42-F144 HydrophobicContact CE2-CG 4.01Å; Y42-F144 AromaticContact CE2-CZ 3.72Å; Y42-F144 HydrophobicContact CE2-CZ 3.72Å; Y47-F144 HydrophobicContact CE2-CE1 4.46Å; Y47-F144 HydrophobicContact CE2-CZ 4.05Å; Y52-F144 HydrophobicContact CE1-CD1 4.16Å; Y52-F144 AromaticContact CE1-CE1 3.76Å; Y52-F144 HydrophobicContact CE1-CE1 3.76Å; T142-F144 PolarHBondContact O-N 2.78Å; F144-L146 VanDerWaalsContact C-N 3.3Å; F144-L146 PolarHBondContact O-N 2.93Å
145N96.3Very high96.7Very high12 Ų1221 Ų216%0.06410%0.099CC..Hα-helixtrans-80-7.4-179.3-59.7139.3000113.5L140 N141 T142 L143 S147 E148 T149L140-N145 WeakPolarHBondContact CA-OD1 3.44Å; L140-N145 HydrophobicContact CB-CB 3.8Å; L140-N145 HydrophobicContact CD2-CB 3.76Å; L140-N145 HydrophobicContact CG-CB 4.4Å; N141-N145 PolarHBondContact N-OD1 2.84Å; N141-N145 VanDerWaalsContact N-OD1 3.12Å; T142-N145 PolarHBondContact N-OD1 3.22Å; T142-N145 VanDerWaalsContact N-OD1 3.12Å; T142-N145 WeakPolarHBondContact O-CB 3.46Å; T142-N145 PolarHBondContact O-N 3.22Å; T142-N145 PolarHBondContact OG1-OD1 2.85Å; L143-N145 PolarHBondContact O-N 3.03Å; L143-N145 VanDerWaalsContact O-N 3.14Å; N145-S147 PolarHBondContact O-N 3.12Å; N145-E148 PolarHBondContact ND2-OE2 3.19Å; N145-E148 PolarHBondContact O-N 3Å; N145-T149 WeakPolarHBondContact O-CB 3.44Å; N145-T149 PolarHBondContact O-N 3.45Å; N145-T149 PolarHBondContact O-OG1 3.47Å
146L97.8Very high96.9Very high14 Ų1416.3 Ų16.37%0.0737%0.074CC..Hα-helixtrans-62.4-43.5-177.7-67178.2000111.8E53 P83 R85 L143 F144 E148 T149 Y150E53-L146 HydrophobicContact CG-CB 4.26Å; E53-L146 HydrophobicContact CG-CD1 4.13Å; P83-L146 HydrophobicContact CB-CD2 4.04Å; P83-L146 HydrophobicContact CG-CB 4.42Å; P83-L146 HydrophobicContact CG-CD2 4.4Å; R85-L146 HydrophobicContact CB-CD2 4.31Å; L143-L146 HydrophobicContact CD2-CD1 3.62Å; L143-L146 HydrophobicContact CD2-CG 4.35Å; L143-L146 WeakPolarHBondContact O-CB 3.18Å; L143-L146 WeakPolarHBondContact O-CG 3.26Å; L143-L146 PolarHBondContact O-N 2.92Å; L143-L146 VanDerWaalsContact O-N 3.11Å; F144-L146 VanDerWaalsContact C-N 3.3Å; F144-L146 PolarHBondContact O-N 2.93Å; L146-E148 PolarHBondContact O-N 2.74Å; L146-T149 WeakPolarHBondContact O-CB 3.09Å; L146-T149 PolarHBondContact O-N 2.89Å; L146-Y150 PolarHBondContact O-N 3.39Å
147S97.3Very high96.9Very high5 Ų514.2 Ų14.24%0.0357%0.067CC..Hα-helixtrans-61.5-42.9175.9-520000112E53 N145 L151E53-S147 WeakPolarHBondContact CA-OG 3.47Å; E53-S147 PolarHBondContact O-OG 2.89Å; N145-S147 PolarHBondContact O-N 3.12Å; S147-L151 WeakPolarHBondContact O-CB 3.34Å; S147-L151 PolarHBondContact O-N 2.75Å
148E97Very high96.9Very high3 Ų314 Ų141%0.0147%0.067CC..Hα-helixtrans-66.5-42.1177.1-62.6176.8102.800112L60 N145 L146 Y150 L151 Y152 V188 R189 M192L60-E148 HydrophobicContact CD1-CG 3.95Å; N145-E148 PolarHBondContact ND2-OE2 3.19Å; N145-E148 PolarHBondContact O-N 3Å; L146-E148 PolarHBondContact O-N 2.74Å; E148-Y150 VanDerWaalsContact C-N 3.31Å; E148-Y150 PolarHBondContact O-N 3.46Å; E148-L151 PolarHBondContact O-N 3.41Å; E148-Y152 VanDerWaalsContact O-CB 3.3Å; E148-Y152 WeakPolarHBondContact O-CB 3.42Å; E148-Y152 PolarHBondContact O-N 2.68Å; E148-V188 HydrophobicContact CB-CG1 4.13Å; E148-V188 HydrophobicContact CG-CG1 4.23Å; E148-R189 WeakPolarHBondContact OE1-CD 3.46Å; E148-R189 IonicContact OE1-CZ 3.7Å; E148-R189 IonicContact OE1-NE 3.73Å; E148-R189 IonicContact OE1-NH1 2.78Å; E148-R189 PolarHBondContact OE1-NH1 3.38Å; E148-R189 IonicContact OE2-NH1 3.29Å; E148-R189 PolarHBondContact OE2-NH1 3.04Å; E148-M192 HydrophobicContact CG-CB 4.41Å; E148-M192 HydrophobicContact CG-CE 3.56Å; E148-M192 HydrophobicContact CG-CG 4.42Å; E148-M192 WeakPolarHBondContact OE1-CB 3.36Å
149T98.3Very high97Very high2 Ų210.7 Ų10.71%0.0125%0.054CC..Hα-helixtrans-57.1-49177.9-54.70000109.9P83 L96 L140 N145 L146 A153P83-T149 HydrophobicContact CB-CG2 4.03Å; L96-T149 HydrophobicContact CD1-CG2 4.09Å; L140-T149 HydrophobicContact CD1-CG2 4.28Å; L140-T149 WeakPolarHBondContact CD1-OG1 3.48Å; N145-T149 WeakPolarHBondContact O-CB 3.44Å; N145-T149 PolarHBondContact O-N 3.45Å; N145-T149 PolarHBondContact O-OG1 3.47Å; L146-T149 WeakPolarHBondContact O-CB 3.09Å; L146-T149 PolarHBondContact O-N 2.89Å; T149-A153 PolarHBondContact O-N 3.29Å
150Y98.6Very high97Very high18 Ų1810.9 Ų10.97%0.0716%0.057CC..Hα-helixtrans-70.3-43.9-179.2-176.6-110000112F57 T77 Y78 D79 F82 F112 L146 E148 Y152 A153 C154F57-Y150 AromaticContact CD2-CD1 3.71Å; F57-Y150 HydrophobicContact CD2-CD1 3.71Å; F57-Y150 HydrophobicContact CD2-CE1 4.4Å; F57-Y150 AromaticContact CE2-CD1 3.42Å; F57-Y150 HydrophobicContact CE2-CD1 3.42Å; F57-Y150 VanDerWaalsContact CE2-CD1 3.42Å; F57-Y150 AromaticContact CE2-CE1 3.81Å; F57-Y150 HydrophobicContact CE2-CE1 3.81Å; F57-Y150 HydrophobicContact CZ-CD1 4.04Å; F57-Y150 AromaticContact CZ-CE1 3.95Å; F57-Y150 HydrophobicContact CZ-CE1 3.95Å; T77-Y150 WeakPolarHBondContact O-CE1 3.43Å; T77-Y150 PolarHBondContact O-OH 3.19Å; T77-Y150 VanDerWaalsContact O-OH 3.06Å; Y78-Y150 AromaticContact CD2-CD1 3.65Å; Y78-Y150 HydrophobicContact CD2-CD1 3.65Å; Y78-Y150 HydrophobicContact CD2-CE1 4.39Å; Y78-Y150 HydrophobicContact CD2-CG 4.13Å; Y78-Y150 HydrophobicContact CE2-CD1 4.22Å; Y78-Y150 HydrophobicContact CE2-CG 4.24Å; D79-Y150 HydrophobicContact CB-CE1 4.37Å; D79-Y150 HydrophobicContact CB-CE2 3.71Å; D79-Y150 WeakPolarHBondContact CB-OH 3.34Å; F82-Y150 HydrophobicContact CB-CD2 3.8Å; F82-Y150 HydrophobicContact CB-CE2 3.97Å; F82-Y150 AromaticContact CD1-CD2 3.73Å; F82-Y150 HydrophobicContact CD1-CD2 3.73Å; F82-Y150 HydrophobicContact CD1-CE2 4.48Å; F82-Y150 AromaticContact CG-CD2 3.97Å; F82-Y150 HydrophobicContact CG-CD2 3.97Å; F82-Y150 HydrophobicContact CG-CE2 4.31Å; F112-Y150 HydrophobicContact CE1-CD2 4.11Å; F112-Y150 AromaticContact CE1-CE2 3.64Å; F112-Y150 HydrophobicContact CE1-CE2 3.64Å; F112-Y150 HydrophobicContact CZ-CD2 4.46Å; F112-Y150 AromaticContact CZ-CE2 3.77Å; F112-Y150 HydrophobicContact CZ-CE2 3.77Å; L146-Y150 PolarHBondContact O-N 3.39Å; E148-Y150 VanDerWaalsContact C-N 3.31Å; E148-Y150 PolarHBondContact O-N 3.46Å; Y150-Y152 VanDerWaalsContact C-N 3.32Å; Y150-Y152 PolarHBondContact O-N 2.78Å; Y150-A153 WeakPolarHBondContact O-CB 3.47Å; Y150-A153 PolarHBondContact O-N 3.06Å; Y150-A153 VanDerWaalsContact O-N 3.15Å; Y150-C154 VanDerWaalsContact CE1-SG 3.58Å; Y150-C154 PolarHBondContact O-N 2.68Å; Y150-C154 PolarHBondContact O-SG 3.05Å; Y150-C154 VanDerWaalsContact O-SG 3.32Å
151L98.6Very high97.1Very high2 Ų218.2 Ų18.21%0.019%0.085CC..Hα-helixtrans-58.5-44.1175.717961.1000112F57 L60 R61 M64 S147 E148 A153 C154 L155 V188F57-L151 HydrophobicContact CD2-CB 4.03Å; F57-L151 HydrophobicContact CE2-CB 3.86Å; F57-L151 HydrophobicContact CE2-CD1 3.96Å; F57-L151 HydrophobicContact CZ-CD1 4.45Å; L60-L151 HydrophobicContact CB-CD2 3.58Å; L60-L151 HydrophobicContact CD1-CD2 4.24Å; L60-L151 HydrophobicContact CG-CD2 4.45Å; R61-L151 HydrophobicContact CB-CD1 4.45Å; M64-L151 HydrophobicContact CG-CD2 3.98Å; S147-L151 WeakPolarHBondContact O-CB 3.34Å; S147-L151 PolarHBondContact O-N 2.75Å; E148-L151 PolarHBondContact O-N 3.41Å; L151-A153 VanDerWaalsContact C-N 3.3Å; L151-A153 PolarHBondContact O-N 3.23Å; L151-C154 WeakPolarHBondContact O-CB 3.1Å; L151-C154 PolarHBondContact O-N 2.81Å; L151-C154 VanDerWaalsContact O-N 3.13Å; L151-L155 HydrophobicContact CD1-CG 4.33Å; L151-L155 HydrophobicContact CG-CD1 4.27Å; L151-L155 HydrophobicContact CG-CG 4.44Å; L151-L155 WeakPolarHBondContact O-CG 3.29Å; L151-L155 PolarHBondContact O-N 3.09Å; L151-V188 HydrophobicContact CD2-CG1 4.46Å; L151-V188 HydrophobicContact CD2-CG2 4.49Å
152Y98.6Very high97.2Very high1 Ų118.6 Ų18.60%0.0049%0.088CC..Hα-helixtrans-61.4-41.1177.7-171.6-95.5000111.7L89 L96 E148 Y150 L155 V156 Y181 M184 F185L89-Y152 HydrophobicContact CD1-CD1 3.43Å; L89-Y152 VanDerWaalsContact CD1-CD1 3.43Å; L89-Y152 HydrophobicContact CD1-CD2 3.88Å; L89-Y152 HydrophobicContact CD1-CE1 3.54Å; L89-Y152 HydrophobicContact CD1-CE2 3.99Å; L89-Y152 HydrophobicContact CD1-CG 3.58Å; L89-Y152 HydrophobicContact CD2-CE1 4.43Å; L89-Y152 HydrophobicContact CG-CD1 4.23Å; L89-Y152 HydrophobicContact CG-CE1 3.9Å; L96-Y152 HydrophobicContact CD2-CD1 4.12Å; L96-Y152 HydrophobicContact CG-CD1 4.48Å; E148-Y152 VanDerWaalsContact O-CB 3.3Å; E148-Y152 WeakPolarHBondContact O-CB 3.42Å; E148-Y152 PolarHBondContact O-N 2.68Å; Y150-Y152 VanDerWaalsContact C-N 3.32Å; Y150-Y152 PolarHBondContact O-N 2.78Å; Y152-L155 PolarHBondContact O-N 2.98Å; Y152-V156 HydrophobicContact CD1-CG2 4.02Å; Y152-V156 HydrophobicContact CE1-CG2 3.64Å; Y152-V156 WeakPolarHBondContact O-CG2 3.49Å; Y152-V156 PolarHBondContact O-N 3.37Å; Y152-Y181 WeakPolarHBondContact OH-CB 3.38Å; Y152-Y181 PolarHBondContact OH-O 3.2Å; Y152-M184 HydrophobicContact CD2-CE 4.02Å; Y152-M184 HydrophobicContact CE1-CE 4.48Å; Y152-M184 HydrophobicContact CE2-CE 3.41Å; Y152-M184 VanDerWaalsContact CE2-CE 3.41Å; Y152-F185 HydrophobicContact CD2-CB 4.24Å; Y152-F185 HydrophobicContact CD2-CD2 4.05Å; Y152-F185 HydrophobicContact CE2-CB 3.65Å; Y152-F185 HydrophobicContact CE2-CD2 4.2Å; Y152-F185 HydrophobicContact CE2-CG 4.38Å
153A98.6Very high97.3Very high1 Ų124.7 Ų24.71%0.00813%0.126CC..Hα-helixtrans-61.1-43.6172.700000112F82 L96 G111 F112 T149 Y150 L151 L155 V156 D157F82-A153 HydrophobicContact CD1-CB 4.37Å; F82-A153 HydrophobicContact CE1-CB 3.5Å; F82-A153 VanDerWaalsContact CE1-CB 3.5Å; F82-A153 HydrophobicContact CZ-CB 3.64Å; L96-A153 HydrophobicContact CD1-CB 3.93Å; G111-A153 WeakPolarHBondContact CA-O 3.36Å; F112-A153 HydrophobicContact CD1-CB 4.17Å; F112-A153 HydrophobicContact CE1-CB 3.74Å; F112-A153 HydrophobicContact CZ-CB 4.4Å; T149-A153 PolarHBondContact O-N 3.29Å; Y150-A153 WeakPolarHBondContact O-CB 3.47Å; Y150-A153 PolarHBondContact O-N 3.06Å; Y150-A153 VanDerWaalsContact O-N 3.15Å; L151-A153 VanDerWaalsContact C-N 3.3Å; L151-A153 PolarHBondContact O-N 3.23Å; A153-L155 VanDerWaalsContact C-N 3.32Å; A153-L155 PolarHBondContact O-N 3.24Å; A153-V156 PolarHBondContact O-N 3.17Å; A153-D157 VanDerWaalsContact O-CB 3.23Å; A153-D157 WeakPolarHBondContact O-CB 3.37Å; A153-D157 PolarHBondContact O-N 3.47Å
154C98.6Very high97.3Very high1 Ų129.5 Ų29.51%0.00714%0.143CC..Hα-helixtrans-57.7-43.6174.2-65.20000112Y76 F112 Y150 L151 F158Y76-C154 HydrophobicContact CD1-CB 4Å; Y76-C154 HydrophobicContact CD2-CB 3.99Å; Y76-C154 HydrophobicContact CE1-CB 4.09Å; Y76-C154 HydrophobicContact CE2-CB 4.1Å; Y76-C154 HydrophobicContact CG-CB 3.95Å; F112-C154 HydrophobicContact CZ-CB 4.36Å; F112-C154 VanDerWaalsContact CZ-SG 3.59Å; Y150-C154 VanDerWaalsContact CE1-SG 3.58Å; Y150-C154 PolarHBondContact O-N 2.68Å; Y150-C154 PolarHBondContact O-SG 3.05Å; Y150-C154 VanDerWaalsContact O-SG 3.32Å; L151-C154 WeakPolarHBondContact O-CB 3.1Å; L151-C154 PolarHBondContact O-N 2.81Å; L151-C154 VanDerWaalsContact O-N 3.13Å; C154-F158 WeakPolarHBondContact O-CB 3.31Å; C154-F158 PolarHBondContact O-N 2.74Å
155L98.6Very high97.5Very high0 Ų029.3 Ų29.30%014%0.142CC..Hα-helixtrans-65.8-51.2-179.5-67.5173000111M64 Y69 I73 L151 Y152 A153 D157 F158 F159 M184 V188M64-L155 HydrophobicContact CE-CD1 3.93Å; Y69-L155 HydrophobicContact CD1-CD2 4Å; Y69-L155 HydrophobicContact CE1-CD1 4.43Å; Y69-L155 HydrophobicContact CE1-CD2 4.29Å; I73-L155 HydrophobicContact CD1-CD2 4.18Å; I73-L155 HydrophobicContact CG2-CD2 4.14Å; L151-L155 HydrophobicContact CD1-CG 4.33Å; L151-L155 HydrophobicContact CG-CD1 4.27Å; L151-L155 HydrophobicContact CG-CG 4.44Å; L151-L155 WeakPolarHBondContact O-CG 3.29Å; L151-L155 PolarHBondContact O-N 3.09Å; Y152-L155 PolarHBondContact O-N 2.98Å; A153-L155 VanDerWaalsContact C-N 3.32Å; A153-L155 PolarHBondContact O-N 3.24Å; L155-D157 VanDerWaalsContact C-N 3.29Å; L155-D157 PolarHBondContact O-N 3.48Å; L155-F158 PolarHBondContact O-N 2.93Å; L155-F159 HydrophobicContact CB-CD2 4.42Å; L155-F159 HydrophobicContact CB-CE2 4.33Å; L155-F159 HydrophobicContact CD2-CE2 4.15Å; L155-F159 WeakPolarHBondContact O-CD2 3.22Å; L155-F159 PolarHBondContact O-N 3.09Å; L155-M184 HydrophobicContact CB-CE 4.2Å; L155-M184 HydrophobicContact CB-SD 3.77Å; L155-M184 HydrophobicContact CD1-CG 4.13Å; L155-M184 HydrophobicContact CD1-SD 4.4Å; L155-V188 HydrophobicContact CD1-CG2 3.61Å
156V98.5Very high97.5Very high0 Ų032.2 Ų32.20%016%0.163CC..Hα-helixtrans-56.2-47.1177.41750000110.4H110 G111 Y152 A153 T160 Y181 M184H110-V156 WeakPolarHBondContact NE2-CG1 3.47Å; G111-V156 VanDerWaalsContact N-CG1 3.29Å; Y152-V156 HydrophobicContact CD1-CG2 4.02Å; Y152-V156 HydrophobicContact CE1-CG2 3.64Å; Y152-V156 WeakPolarHBondContact O-CG2 3.49Å; Y152-V156 PolarHBondContact O-N 3.37Å; A153-V156 PolarHBondContact O-N 3.17Å; V156-T160 WeakPolarHBondContact O-CB 2.92Å; V156-T160 PolarHBondContact O-N 3.32Å; V156-T160 PolarHBondContact O-OG1 2.5Å; V156-Y181 HydrophobicContact CG1-CE1 4.32Å; V156-Y181 HydrophobicContact CG2-CD1 4.29Å; V156-Y181 HydrophobicContact CG2-CE1 4.18Å; V156-M184 HydrophobicContact CG2-CE 3.53Å
157D98.2Very high97.5Very high19 Ų1935.8 Ų35.810%0.10218%0.182CC..Hα-helixtrans-62.4-44.8177.4170.671000112.7Y76 F112 A153 L155 T160 R161Y76-D157 PolarHBondContact OH-OD2 2.97Å; F112-D157 HydrophobicContact CD2-CB 3.61Å; F112-D157 WeakPolarHBondContact CD2-OD2 3.21Å; F112-D157 HydrophobicContact CE2-CB 3.95Å; F112-D157 HydrophobicContact CG-CB 4.3Å; A153-D157 VanDerWaalsContact O-CB 3.23Å; A153-D157 WeakPolarHBondContact O-CB 3.37Å; A153-D157 PolarHBondContact O-N 3.47Å; L155-D157 VanDerWaalsContact C-N 3.29Å; L155-D157 PolarHBondContact O-N 3.48Å; D157-T160 PolarHBondContact O-N 2.94Å; D157-R161 VanDerWaalsContact CG-NE 3.32Å; D157-R161 WeakPolarHBondContact O-CB 3.13Å; D157-R161 WeakPolarHBondContact O-CG 3.21Å; D157-R161 PolarHBondContact O-N 3.46Å; D157-R161 VanDerWaalsContact O-N 3.09Å; D157-R161 IonicContact OD1-CZ 3.59Å; D157-R161 IonicContact OD1-NE 2.59Å; D157-R161 PolarHBondContact OD1-NE 2.87Å; D157-R161 IonicContact OD1-NH2 2.92Å; D157-R161 IonicContact OD2-CZ 3.95Å; D157-R161 VanDerWaalsContact OD2-CZ 3.27Å; D157-R161 IonicContact OD2-NE 3.52Å; D157-R161 PolarHBondContact OD2-NE 2.93Å; D157-R161 VanDerWaalsContact OD2-NE 3.14Å; D157-R161 IonicContact OD2-NH2 3.09Å; D157-R161 PolarHBondContact OD2-NH2 3.44Å
158F98.3Very high97.5Very high6 Ų639 Ų393%0.02620%0.198CC..Hα-helixtrans-58.3-54.4178.3170.8-99.3000111.8P70 E72 I73 Y76 C154 L155 T160 R161 C162P70-F158 HydrophobicContact CB-CE1 3.96Å; P70-F158 HydrophobicContact CB-CZ 3.87Å; P70-F158 HydrophobicContact CG-CE1 3.89Å; P70-F158 HydrophobicContact CG-CZ 4.29Å; E72-F158 HydrophobicContact CB-CE2 3.56Å; E72-F158 HydrophobicContact CB-CZ 3.97Å; E72-F158 HydrophobicContact CG-CE2 4.42Å; I73-F158 HydrophobicContact CG2-CD1 4.12Å; I73-F158 HydrophobicContact CG2-CD2 4.4Å; I73-F158 HydrophobicContact CG2-CE1 4.36Å; I73-F158 HydrophobicContact CG2-CG 4.14Å; Y76-F158 HydrophobicContact CE2-CB 4.1Å; Y76-F158 HydrophobicContact CE2-CD2 4.46Å; C154-F158 WeakPolarHBondContact O-CB 3.31Å; C154-F158 PolarHBondContact O-N 2.74Å; L155-F158 PolarHBondContact O-N 2.93Å; F158-T160 VanDerWaalsContact C-N 3.34Å; F158-R161 PolarHBondContact O-N 3.19Å; F158-C162 VanDerWaalsContact O-CB 3.27Å; F158-C162 WeakPolarHBondContact O-CB 3.38Å; F158-C162 PolarHBondContact O-N 3.49Å
159F98.3Very high97.4Very high4 Ų445.8 Ų45.82%0.01822%0.224CC..Hα-helixtrans-67.8-37.1-177.6-71-69.4000111.5Y69 P70 L155 R161 C162 Y165 F172 M179 M184Y69-F159 HydrophobicContact CD1-CE2 4.15Å; Y69-F159 AromaticContact CD1-CZ 3.95Å; Y69-F159 HydrophobicContact CD1-CZ 3.95Å; Y69-F159 HydrophobicContact CE1-CE2 4.07Å; Y69-F159 HydrophobicContact CE1-CZ 4.12Å; P70-F159 HydrophobicContact CG-CE1 4.14Å; P70-F159 HydrophobicContact CG-CZ 4.28Å; L155-F159 HydrophobicContact CB-CD2 4.42Å; L155-F159 HydrophobicContact CB-CE2 4.33Å; L155-F159 HydrophobicContact CD2-CE2 4.15Å; L155-F159 WeakPolarHBondContact O-CD2 3.22Å; L155-F159 PolarHBondContact O-N 3.09Å; F159-R161 VanDerWaalsContact C-N 3.29Å; F159-R161 PolarHBondContact O-N 2.65Å; F159-C162 PolarHBondContact O-N 3.35Å; F159-Y165 AromaticContact CD1-CD1 3.96Å; F159-Y165 HydrophobicContact CD1-CD1 3.96Å; F159-Y165 AromaticContact CD1-CD2 3.84Å; F159-Y165 HydrophobicContact CD1-CD2 3.84Å; F159-Y165 AromaticContact CD1-CE1 3.85Å; F159-Y165 HydrophobicContact CD1-CE1 3.85Å; F159-Y165 AromaticContact CD1-CE2 3.72Å; F159-Y165 HydrophobicContact CD1-CE2 3.72Å; F159-Y165 AromaticContact CD1-CG 3.97Å; F159-Y165 HydrophobicContact CD1-CG 3.97Å; F159-Y165 AromaticContact CD1-CZ 3.74Å; F159-Y165 HydrophobicContact CE1-CD1 4.36Å; F159-Y165 HydrophobicContact CE1-CD2 4.47Å; F159-Y165 AromaticContact CE1-CE1 3.79Å; F159-Y165 HydrophobicContact CE1-CE1 3.79Å; F159-Y165 AromaticContact CE1-CE2 3.9Å; F159-Y165 HydrophobicContact CE1-CE2 3.9Å; F159-Y165 AromaticContact CE1-CZ 3.54Å; F159-F172 HydrophobicContact CB-CB 4.48Å; F159-F172 HydrophobicContact CB-CD1 3.67Å; F159-F172 HydrophobicContact CB-CD2 3.52Å; F159-F172 HydrophobicContact CB-CE1 3.63Å; F159-F172 HydrophobicContact CB-CE2 3.46Å; F159-F172 VanDerWaalsContact CB-CE2 3.46Å; F159-F172 HydrophobicContact CB-CG 3.61Å; F159-F172 HydrophobicContact CB-CZ 3.52Å; F159-F172 HydrophobicContact CD2-CD2 4.27Å; F159-F172 HydrophobicContact CD2-CE2 4.23Å; F159-F172 AromaticContact CG-CD2 3.96Å; F159-F172 HydrophobicContact CG-CD2 3.96Å; F159-F172 HydrophobicContact CG-CE2 4.13Å; F159-F172 HydrophobicContact CG-CG 4.28Å; F159-M179 HydrophobicContact CD1-CE 4.13Å; F159-M179 HydrophobicContact CD2-CE 3.7Å; F159-M179 HydrophobicContact CE1-CE 3.9Å; F159-M179 HydrophobicContact CE2-CE 3.5Å; F159-M179 VanDerWaalsContact CE2-CE 3.5Å; F159-M179 HydrophobicContact CG-CE 4.06Å; F159-M179 HydrophobicContact CZ-CE 3.59Å; F159-M179 HydrophobicContact CZ-SD 4.42Å; F159-M184 HydrophobicContact CD2-SD 3.96Å; F159-M184 HydrophobicContact CE2-SD 4.04Å
160T97.4Very high97.4Very high48 Ų4851.7 Ų51.729%0.29425%0.249SC..Hα-helixtrans-59.9-38.4176.6-61.10000112.5V156 D157 F158 N167V156-T160 WeakPolarHBondContact O-CB 2.92Å; V156-T160 PolarHBondContact O-N 3.32Å; V156-T160 PolarHBondContact O-OG1 2.5Å; D157-T160 PolarHBondContact O-N 2.94Å; F158-T160 VanDerWaalsContact C-N 3.34Å; T160-N167 WeakPolarHBondContact CA-OD1 3.3Å; T160-N167 PolarHBondContact O-ND2 3.4Å
161R96.3Very high97.3Very high156 Ų15650.8 Ų50.859%0.58925%0.246SC*.Hα-helixtrans-89.2-13.3-178.2-65.6-168.5-70.3139.6-4.6113.8Y76 D157 F158 F159 T163Y76-R161 PolarHBondContact OH-NH2 2.89Å; D157-R161 VanDerWaalsContact CG-NE 3.32Å; D157-R161 WeakPolarHBondContact O-CB 3.13Å; D157-R161 WeakPolarHBondContact O-CG 3.21Å; D157-R161 PolarHBondContact O-N 3.46Å; D157-R161 VanDerWaalsContact O-N 3.09Å; D157-R161 IonicContact OD1-CZ 3.59Å; D157-R161 IonicContact OD1-NE 2.59Å; D157-R161 PolarHBondContact OD1-NE 2.87Å; D157-R161 IonicContact OD1-NH2 2.92Å; D157-R161 IonicContact OD2-CZ 3.95Å; D157-R161 VanDerWaalsContact OD2-CZ 3.27Å; D157-R161 IonicContact OD2-NE 3.52Å; D157-R161 PolarHBondContact OD2-NE 2.93Å; D157-R161 VanDerWaalsContact OD2-NE 3.14Å; D157-R161 IonicContact OD2-NH2 3.09Å; D157-R161 PolarHBondContact OD2-NH2 3.44Å; F158-R161 PolarHBondContact O-N 3.19Å; F159-R161 VanDerWaalsContact C-N 3.29Å; F159-R161 PolarHBondContact O-N 2.65Å; R161-T163 PolarHBondContact O-N 2.85Å
162C95.4Very high97.3Very high23 Ų2350.8 Ų50.816%0.15525%0.245CC..  trans-85.1113.4-175.9-173.50000110.9F158 F159 R164 Y165F158-C162 VanDerWaalsContact O-CB 3.27Å; F158-C162 WeakPolarHBondContact O-CB 3.38Å; F158-C162 PolarHBondContact O-N 3.49Å; F159-C162 PolarHBondContact O-N 3.35Å; C162-R164 PolarHBondContact O-N 2.92Å; C162-Y165 HydrophobicContact CB-CD2 3.79Å; C162-Y165 HydrophobicContact CB-CE2 4.28Å; C162-Y165 PolarHBondContact O-N 3.49Å
163T94.1Very high97.3Very high147 Ų14754.4 Ų54.490%0.90226%0.263SS*.THydrogen-bonded Turntrans-62.5-12.7-178.654.60000114.8R161 Y165R161-T163 PolarHBondContact O-N 2.85Å; T163-Y165 PolarHBondContact O-N 3.48Å
164R95.8Very high97.2Very high109 Ų10958.5 Ų58.541%0.41128%0.281SS..THydrogen-bonded Turntrans-68.4-24.3172.9-65-173.7-63.4-155.6-4.9112.5E72 C162 H174E72-R164 IonicContact OE1-CZ 2.65Å; E72-R164 VanDerWaalsContact OE1-CZ 3.25Å; E72-R164 IonicContact OE1-NH1 3.35Å; E72-R164 PolarHBondContact OE1-NH1 3.41Å; E72-R164 IonicContact OE1-NH2 2.74Å; E72-R164 PolarHBondContact OE1-NH2 3.04Å; E72-R164 IonicContact OE2-NH2 3.04Å; C162-R164 PolarHBondContact O-N 2.92Å; R164-H174 PolarHBondContact O-ND1 3.03Å
165Y96.8Very high97.1Very high45 Ų4561.1 Ų61.118%0.17631%0.308CS..SBendtrans-109.3138.5-174.1-59.8-93.4000110.4P70 F159 C162 T163 F172 Q173 H174P70-Y165 WeakPolarHBondContact CG-OH 3.4Å; F159-Y165 AromaticContact CD1-CD1 3.96Å; F159-Y165 HydrophobicContact CD1-CD1 3.96Å; F159-Y165 AromaticContact CD1-CD2 3.84Å; F159-Y165 HydrophobicContact CD1-CD2 3.84Å; F159-Y165 AromaticContact CD1-CE1 3.85Å; F159-Y165 HydrophobicContact CD1-CE1 3.85Å; F159-Y165 AromaticContact CD1-CE2 3.72Å; F159-Y165 HydrophobicContact CD1-CE2 3.72Å; F159-Y165 AromaticContact CD1-CG 3.97Å; F159-Y165 HydrophobicContact CD1-CG 3.97Å; F159-Y165 AromaticContact CD1-CZ 3.74Å; F159-Y165 HydrophobicContact CE1-CD1 4.36Å; F159-Y165 HydrophobicContact CE1-CD2 4.47Å; F159-Y165 AromaticContact CE1-CE1 3.79Å; F159-Y165 HydrophobicContact CE1-CE1 3.79Å; F159-Y165 AromaticContact CE1-CE2 3.9Å; F159-Y165 HydrophobicContact CE1-CE2 3.9Å; F159-Y165 AromaticContact CE1-CZ 3.54Å; C162-Y165 HydrophobicContact CB-CD2 3.79Å; C162-Y165 HydrophobicContact CB-CE2 4.28Å; C162-Y165 PolarHBondContact O-N 3.49Å; T163-Y165 PolarHBondContact O-N 3.48Å; Y165-F172 HydrophobicContact CD1-CB 4.3Å; Y165-Q173 CarbonylContact C-O 3.49Å; Y165-Q173 WeakPolarHBondContact CA-O 3.4Å; Y165-H174 HydrophobicContact CD1-CB 3.63Å; Y165-H174 HydrophobicContact CE1-CB 3.7Å; Y165-H174 HydrophobicContact CG-CB 4.49Å
166S97.6Very high97Very high73 Ų7369.3 Ų69.351%0.5135%0.352SS..EExtended strand (participates in β ladder)trans-87.5125.8168.7-620000109.4L168 F172 Q173S166-L168 PolarHBondContact O-N 2.86Å; S166-F172 WeakPolarHBondContact O-CA 3.46Å; S166-Q173 PolarHBondContact N-O 3.04Å; S166-Q173 PolarHBondContact O-N 3.06Å
167N97.2Very high96.9Very high88 Ų8875.4 Ų75.447%0.47138%0.384SS..EExtended strand (participates in β ladder)trans-76.9117.8178.4-64.8-27.2000109.9T160 F172T160-N167 WeakPolarHBondContact CA-OD1 3.3Å; T160-N167 PolarHBondContact O-ND2 3.4Å; N167-F172 VanDerWaalsContact OD1-CD1 3.26Å; N167-F172 WeakPolarHBondContact OD1-CD1 3.4Å; N167-F172 VanDerWaalsContact OD1-CE1 3.3Å; N167-F172 WeakPolarHBondContact OD1-CE1 3.47Å
168L96.9Very high96.9Very high72 Ų7279.8 Ų79.838%0.37740%0.403SS..EExtended strand (participates in β ladder)trans-112.4160.9174.5-59.4-180000109.8S166 K170 G171 Q173 F178S166-L168 PolarHBondContact O-N 2.86Å; L168-K170 PolarHBondContact O-N 3.24Å; L168-G171 CarbonylContact C-O 3.56Å; L168-G171 WeakPolarHBondContact CA-O 3.48Å; L168-G171 WeakPolarHBondContact CB-O 3.35Å; L168-G171 PolarHBondContact N-O 2.93Å; L168-G171 PolarHBondContact O-N 2.83Å; L168-Q173 HydrophobicContact CD1-CB 3.85Å; L168-Q173 HydrophobicContact CG-CB 4.38Å; L168-F178 HydrophobicContact CB-CE2 4.43Å; L168-F178 HydrophobicContact CD1-CD2 3.84Å; L168-F178 HydrophobicContact CD1-CE2 3.76Å
169R95.1Very high96.9Very high146 Ų14681.3 Ų81.355%0.55141%0.41SS*.THydrogen-bonded Turntrans-58.3-27.9-177.7-172.6173.2-178.3177.45.1114.1L93L93-R169 HydrophobicContact CD2-CG 4.03Å
170K97.4Very high97Very high126 Ų12682.5 Ų82.555%0.54842%0.419SS..THydrogen-bonded Turntrans-115.69.6-175.2-64.3-173.9176.9-178.60113.8T92 L168 F178 S180 Y181T92-K170 HydrophobicContact CG2-CD 4.36Å; T92-K170 HydrophobicContact CG2-CG 4.34Å; T92-K170 WeakPolarHBondContact O-CA 3.25Å; L168-K170 PolarHBondContact O-N 3.24Å; K170-F178 HydrophobicContact CB-CZ 4.34Å; K170-S180 VanDerWaalsContact O-CA 3.29Å; K170-S180 WeakPolarHBondContact O-CA 3.34Å; K170-Y181 VanDerWaalsContact C-CE2 3.45Å; K170-Y181 WeakPolarHBondContact O-CD2 3.33Å; K170-Y181 PolarHBondContact O-N 3.24Å
171G98Very high97Very high0 Ų080.5 Ų80.50%041%0.406CS..EExtended strand (participates in β ladder)trans154.6-152.9-179.700000112.9L168 M179L168-G171 CarbonylContact C-O 3.56Å; L168-G171 WeakPolarHBondContact CA-O 3.48Å; L168-G171 WeakPolarHBondContact CB-O 3.35Å; L168-G171 PolarHBondContact N-O 2.93Å; L168-G171 PolarHBondContact O-N 2.83Å; G171-M179 CarbonylContact C-O 3.58Å; G171-M179 VanDerWaalsContact CA-O 3.29Å; G171-M179 WeakPolarHBondContact CA-O 3.38Å
172F98.4Very high97.1Very high1 Ų177 Ų770%0.00439%0.393CS..EExtended strand (participates in β ladder)trans-125142.6-172.8-54.2-76.5000110.6F159 Y165 S166 N167 M179 Y181 M184F159-F172 HydrophobicContact CB-CB 4.48Å; F159-F172 HydrophobicContact CB-CD1 3.67Å; F159-F172 HydrophobicContact CB-CD2 3.52Å; F159-F172 HydrophobicContact CB-CE1 3.63Å; F159-F172 HydrophobicContact CB-CE2 3.46Å; F159-F172 VanDerWaalsContact CB-CE2 3.46Å; F159-F172 HydrophobicContact CB-CG 3.61Å; F159-F172 HydrophobicContact CB-CZ 3.52Å; F159-F172 HydrophobicContact CD2-CD2 4.27Å; F159-F172 HydrophobicContact CD2-CE2 4.23Å; F159-F172 AromaticContact CG-CD2 3.96Å; F159-F172 HydrophobicContact CG-CD2 3.96Å; F159-F172 HydrophobicContact CG-CE2 4.13Å; F159-F172 HydrophobicContact CG-CG 4.28Å; Y165-F172 HydrophobicContact CD1-CB 4.3Å; S166-F172 WeakPolarHBondContact O-CA 3.46Å; N167-F172 VanDerWaalsContact OD1-CD1 3.26Å; N167-F172 WeakPolarHBondContact OD1-CD1 3.4Å; N167-F172 VanDerWaalsContact OD1-CE1 3.3Å; N167-F172 WeakPolarHBondContact OD1-CE1 3.47Å; F172-M179 HydrophobicContact CD2-CE 3.96Å; F172-M179 PolarHBondContact N-O 2.88Å; F172-M179 PolarHBondContact O-N 3.19Å; F172-Y181 HydrophobicContact CD2-CE1 4.28Å; F172-Y181 HydrophobicContact CE2-CD1 4.11Å; F172-Y181 AromaticContact CE2-CE1 3.39Å; F172-Y181 HydrophobicContact CE2-CE1 3.39Å; F172-Y181 AromaticContact CZ-CE1 3.57Å; F172-Y181 HydrophobicContact CZ-CE1 3.57Å; F172-Y181 AromaticContact CZ-CZ 3.98Å; F172-M184 HydrophobicContact CE2-SD 4.47Å
173Q98.1Very high97.3Very high78 Ų7878 Ų7836%0.36440%0.4SS..EExtended strand (participates in β ladder)trans-118.3134.5176.9-176170.510.200111.6Y165 S166 L168 G175 L177Y165-Q173 CarbonylContact C-O 3.49Å; Y165-Q173 WeakPolarHBondContact CA-O 3.4Å; S166-Q173 PolarHBondContact N-O 3.04Å; S166-Q173 PolarHBondContact O-N 3.06Å; L168-Q173 HydrophobicContact CD1-CB 3.85Å; L168-Q173 HydrophobicContact CG-CB 4.38Å; Q173-G175 PolarHBondContact NE2-O 3.12Å; Q173-G175 VanDerWaalsContact NE2-O 3.16Å; Q173-L177 CarbonylContact C-O 3.12Å; Q173-L177 WeakPolarHBondContact CA-O 3.4Å
174H97.1Very high97.5Very high86 Ų8671 Ų7140%0.39836%0.357SS..EExtended strand (participates in β ladder)trans-136103.8173-177.662.9000110.1R164 Y165 D176 L177R164-H174 PolarHBondContact O-ND1 3.03Å; Y165-H174 HydrophobicContact CD1-CB 3.63Å; Y165-H174 HydrophobicContact CE1-CB 3.7Å; Y165-H174 HydrophobicContact CG-CB 4.49Å; H174-D176 PolarHBondContact O-N 3.04Å; H174-L177 PolarHBondContact N-O 3.42Å; H174-L177 WeakPolarHBondContact O-CB 3.46Å; H174-L177 PolarHBondContact O-N 3.13Å
175G95.8Very high97.6Very high56 Ų5666 Ų6658%0.57734%0.338SS*.THydrogen-bonded Turntrans57.7-125.3-169.900000111Q173 L177Q173-G175 PolarHBondContact NE2-O 3.12Å; Q173-G175 VanDerWaalsContact NE2-O 3.16Å; G175-L177 VanDerWaalsContact C-N 3.29Å
176D96.4Very high97.7Very high172 Ų17268.3 Ų68.392%0.9235%0.351SS*.THydrogen-bonded Turntrans-850.3179.2-57.9-38.5000113.6H174H174-D176 PolarHBondContact O-N 3.04Å
177L97.1Very high97.7Very high129 Ų12967.2 Ų67.268%0.67534%0.339SS*.EExtended strand (participates in β ladder)trans-97119.5179.9-59.9174.2000110.6Q173 H174 G175Q173-L177 CarbonylContact C-O 3.12Å; Q173-L177 WeakPolarHBondContact CA-O 3.4Å; H174-L177 PolarHBondContact N-O 3.42Å; H174-L177 WeakPolarHBondContact O-CB 3.46Å; H174-L177 PolarHBondContact O-N 3.13Å; G175-L177 VanDerWaalsContact C-N 3.29Å
178F98.3Very high97.8Very high111 Ų11163 Ų6349%0.48732%0.317SS..EExtended strand (participates in β ladder)trans-109.3120.8170.4174.8-111.2000110.2L168 K170L168-F178 HydrophobicContact CB-CE2 4.43Å; L168-F178 HydrophobicContact CD1-CD2 3.84Å; L168-F178 HydrophobicContact CD1-CE2 3.76Å; K170-F178 HydrophobicContact CB-CZ 4.34Å
179M98.4Very high97.8Very high38 Ų3861.5 Ų61.519%0.18731%0.306CS..EExtended strand (participates in β ladder)trans-109.7109175.7-173.7-179.866.400109.3Y69 F159 G171 F172 M184Y69-M179 HydrophobicContact CE1-SD 4.02Å; F159-M179 HydrophobicContact CD1-CE 4.13Å; F159-M179 HydrophobicContact CD2-CE 3.7Å; F159-M179 HydrophobicContact CE1-CE 3.9Å; F159-M179 HydrophobicContact CE2-CE 3.5Å; F159-M179 VanDerWaalsContact CE2-CE 3.5Å; F159-M179 HydrophobicContact CG-CE 4.06Å; F159-M179 HydrophobicContact CZ-CE 3.59Å; F159-M179 HydrophobicContact CZ-SD 4.42Å; G171-M179 CarbonylContact C-O 3.58Å; G171-M179 VanDerWaalsContact CA-O 3.29Å; G171-M179 WeakPolarHBondContact CA-O 3.38Å; F172-M179 HydrophobicContact CD2-CE 3.96Å; F172-M179 PolarHBondContact N-O 2.88Å; F172-M179 PolarHBondContact O-N 3.19Å; M179-M184 HydrophobicContact CE-CB 4.5Å; M179-M184 HydrophobicContact CE-CG 4.36Å; M179-M184 HydrophobicContact CE-SD 3.85Å; M179-M184 HydrophobicContact CG-CB 4.34Å; M179-M184 HydrophobicContact SD-CB 4.29Å; M179-M184 HydrophobicContact SD-CG 4.41Å
180S98.7Very high97.9Very high29 Ų2958.2 Ų58.220%0.20330%0.299CS..EExtended strand (participates in β ladder)trans-74.2155.4176.172.30000111.7K170 R182 S183 M184K170-S180 VanDerWaalsContact O-CA 3.29Å; K170-S180 WeakPolarHBondContact O-CA 3.34Å; S180-R182 PolarHBondContact O-N 3.46Å; S180-S183 PolarHBondContact N-OG 3.17Å; S180-S183 VanDerWaalsContact N-OG 3.11Å; S180-S183 PolarHBondContact O-N 2.9Å; S180-S183 PolarHBondContact O-OG 2.95Å; S180-S183 WeakPolarHBondContact OG-CB 3.47Å; S180-S183 PolarHBondContact OG-N 3.09Å; S180-S183 PolarHBondContact OG-OG 3.04Å; S180-M184 WeakPolarHBondContact O-CB 3.48Å; S180-M184 PolarHBondContact O-N 3.32Å
181Y98.8Very high97.9Very high6 Ų652.3 Ų52.32%0.02427%0.274CS..Hα-helixtrans-57.9-34.8170-68-59.5000112.3K91 L93 G94 H110 Y152 V156 K170 F172 M184 F185K91-Y181 CarbonylContact O-C 3.58Å; K91-Y181 WeakPolarHBondContact O-CB 3.23Å; L93-Y181 WeakPolarHBondContact O-CE2 3.42Å; G94-Y181 VanDerWaalsContact CA-CD1 3.4Å; G94-Y181 VanDerWaalsContact N-CD2 3.33Å; H110-Y181 AromaticContact CE1-CZ 3.6Å; H110-Y181 PolarHBondContact CE1-OH 3Å; H110-Y181 PolarHBondContact NE2-OH 3.13Å; Y152-Y181 WeakPolarHBondContact OH-CB 3.38Å; Y152-Y181 PolarHBondContact OH-O 3.2Å; V156-Y181 HydrophobicContact CG1-CE1 4.32Å; V156-Y181 HydrophobicContact CG2-CD1 4.29Å; V156-Y181 HydrophobicContact CG2-CE1 4.18Å; K170-Y181 VanDerWaalsContact C-CE2 3.45Å; K170-Y181 WeakPolarHBondContact O-CD2 3.33Å; K170-Y181 PolarHBondContact O-N 3.24Å; F172-Y181 HydrophobicContact CD2-CE1 4.28Å; F172-Y181 HydrophobicContact CE2-CD1 4.11Å; F172-Y181 AromaticContact CE2-CE1 3.39Å; F172-Y181 HydrophobicContact CE2-CE1 3.39Å; F172-Y181 AromaticContact CZ-CE1 3.57Å; F172-Y181 HydrophobicContact CZ-CE1 3.57Å; F172-Y181 AromaticContact CZ-CZ 3.98Å; Y181-M184 HydrophobicContact CD1-CE 3.95Å; Y181-M184 PolarHBondContact O-N 2.79Å; Y181-F185 WeakPolarHBondContact O-CB 3.17Å; Y181-F185 PolarHBondContact O-N 3.27Å
182R98.6Very high97.7Very high82 Ų8252.8 Ų52.831%0.30928%0.276SS..Hα-helixtrans-63.6-51.1177179178.7-71.3-111.27.5111.8K91 D135 S180 M184 F185 Q186K91-R182 HydrophobicContact CB-CB 4.1Å; K91-R182 HydrophobicContact CB-CG 4.29Å; K91-R182 WeakPolarHBondContact O-CA 3.44Å; K91-R182 WeakPolarHBondContact O-CB 3.33Å; K91-R182 PolarHBondContact O-N 3.01Å; D135-R182 VanDerWaalsContact O-CZ 3.22Å; D135-R182 PolarHBondContact O-NH1 3.47Å; D135-R182 PolarHBondContact O-NH2 3.27Å; D135-R182 IonicContact OD1-CZ 3.1Å; D135-R182 IonicContact OD1-NH1 3.87Å; D135-R182 PolarHBondContact OD1-NH1 2.86Å; D135-R182 IonicContact OD1-NH2 2.72Å; D135-R182 IonicContact OD2-CZ 2.77Å; D135-R182 IonicContact OD2-NH1 2.78Å; D135-R182 PolarHBondContact OD2-NH1 3.32Å; D135-R182 IonicContact OD2-NH2 3.43Å; D135-R182 PolarHBondContact OD2-NH2 2.86Å; S180-R182 PolarHBondContact O-N 3.46Å; R182-M184 VanDerWaalsContact C-N 3.32Å; R182-F185 PolarHBondContact O-N 3.23Å; R182-Q186 WeakPolarHBondContact O-CB 3.29Å; R182-Q186 PolarHBondContact O-N 2.93Å
183S98.4Very high97.4Very high43 Ų4355.7 Ų55.730%0.30129%0.292SS..Hα-helixtrans-64.1-40.7178.654.60000110.8S180 F185 Q186 D187S180-S183 PolarHBondContact N-OG 3.17Å; S180-S183 VanDerWaalsContact N-OG 3.11Å; S180-S183 PolarHBondContact O-N 2.9Å; S180-S183 PolarHBondContact O-OG 2.95Å; S180-S183 WeakPolarHBondContact OG-CB 3.47Å; S180-S183 PolarHBondContact OG-N 3.09Å; S180-S183 PolarHBondContact OG-OG 3.04Å; S183-F185 PolarHBondContact O-N 3.16Å; S183-Q186 WeakPolarHBondContact O-CB 3.37Å; S183-Q186 PolarHBondContact O-N 3.16Å; S183-Q186 VanDerWaalsContact O-N 3.16Å; S183-D187 VanDerWaalsContact O-CG 3.27Å; S183-D187 PolarHBondContact O-N 2.88Å
184M98.6Very high97.3Very high0 Ų056 Ų560%029%0.292CS..Hα-helixtrans-62-41.9175.5-174.5178.574.900112.5Y69 Y152 L155 V156 F159 F172 M179 S180 Y181 R182 Q186 D187 V188Y69-M184 HydrophobicContact CE1-CG 4.21Å; Y69-M184 WeakPolarHBondContact OH-CA 3.32Å; Y152-M184 HydrophobicContact CD2-CE 4.02Å; Y152-M184 HydrophobicContact CE1-CE 4.48Å; Y152-M184 HydrophobicContact CE2-CE 3.41Å; Y152-M184 VanDerWaalsContact CE2-CE 3.41Å; L155-M184 HydrophobicContact CB-CE 4.2Å; L155-M184 HydrophobicContact CB-SD 3.77Å; L155-M184 HydrophobicContact CD1-CG 4.13Å; L155-M184 HydrophobicContact CD1-SD 4.4Å; V156-M184 HydrophobicContact CG2-CE 3.53Å; F159-M184 HydrophobicContact CD2-SD 3.96Å; F159-M184 HydrophobicContact CE2-SD 4.04Å; F172-M184 HydrophobicContact CE2-SD 4.47Å; M179-M184 HydrophobicContact CE-CB 4.5Å; M179-M184 HydrophobicContact CE-CG 4.36Å; M179-M184 HydrophobicContact CE-SD 3.85Å; M179-M184 HydrophobicContact CG-CB 4.34Å; M179-M184 HydrophobicContact SD-CB 4.29Å; M179-M184 HydrophobicContact SD-CG 4.41Å; S180-M184 WeakPolarHBondContact O-CB 3.48Å; S180-M184 PolarHBondContact O-N 3.32Å; Y181-M184 HydrophobicContact CD1-CE 3.95Å; Y181-M184 PolarHBondContact O-N 2.79Å; R182-M184 VanDerWaalsContact C-N 3.32Å; M184-Q186 VanDerWaalsContact C-N 3.35Å; M184-D187 PolarHBondContact O-N 3.1Å; M184-V188 WeakPolarHBondContact O-CG2 3.34Å; M184-V188 PolarHBondContact O-N 3.08Å
185F98.3Very high97.1Very high5 Ų552.1 Ų52.12%0.02228%0.275CS..Hα-helixtrans-66.1-38.8174.2179.3-114.1000112L89 K91 Y138 Y152 Y181 R182 S183 D187 V188 R189L89-F185 HydrophobicContact CD1-CD2 3.29Å; L89-F185 HydrophobicContact CD1-CE2 3.52Å; L89-F185 HydrophobicContact CD1-CG 4.01Å; L89-F185 HydrophobicContact CD1-CZ 4.37Å; L89-F185 HydrophobicContact CD2-CB 4.1Å; L89-F185 HydrophobicContact CD2-CD1 3.99Å; L89-F185 HydrophobicContact CD2-CD2 3.83Å; L89-F185 HydrophobicContact CD2-CE1 4.39Å; L89-F185 HydrophobicContact CD2-CE2 4.27Å; L89-F185 HydrophobicContact CD2-CG 3.67Å; L89-F185 HydrophobicContact CG-CD2 4.2Å; L89-F185 HydrophobicContact CG-CE2 4.42Å; K91-F185 HydrophobicContact CD-CD1 3.79Å; K91-F185 HydrophobicContact CD-CE1 4.21Å; K91-F185 HydrophobicContact CG-CD1 3.75Å; K91-F185 HydrophobicContact CG-CE1 4.39Å; K91-F185 HydrophobicContact CG-CG 4.38Å; Y138-F185 HydrophobicContact CD1-CE1 4.09Å; Y138-F185 HydrophobicContact CD1-CE2 4.46Å; Y138-F185 AromaticContact CD1-CZ 3.47Å; Y138-F185 HydrophobicContact CD1-CZ 3.47Å; Y138-F185 VanDerWaalsContact CD1-CZ 3.47Å; Y138-F185 AromaticContact CD2-CE1 3.98Å; Y138-F185 HydrophobicContact CD2-CE1 3.98Å; Y138-F185 HydrophobicContact CD2-CZ 4.15Å; Y138-F185 AromaticContact CE1-CZ 3.95Å; Y138-F185 HydrophobicContact CE1-CZ 3.95Å; Y138-F185 AromaticContact CG-CE1 3.67Å; Y138-F185 HydrophobicContact CG-CE1 3.67Å; Y138-F185 AromaticContact CG-CZ 3.57Å; Y138-F185 HydrophobicContact CG-CZ 3.57Å; Y152-F185 HydrophobicContact CD2-CB 4.24Å; Y152-F185 HydrophobicContact CD2-CD2 4.05Å; Y152-F185 HydrophobicContact CE2-CB 3.65Å; Y152-F185 HydrophobicContact CE2-CD2 4.2Å; Y152-F185 HydrophobicContact CE2-CG 4.38Å; Y181-F185 WeakPolarHBondContact O-CB 3.17Å; Y181-F185 PolarHBondContact O-N 3.27Å; R182-F185 PolarHBondContact O-N 3.23Å; S183-F185 PolarHBondContact O-N 3.16Å; F185-D187 VanDerWaalsContact C-N 3.33Å; F185-D187 PolarHBondContact O-N 3.11Å; F185-V188 PolarHBondContact O-N 3.35Å; F185-R189 HydrophobicContact CD1-CG 4.23Å; F185-R189 HydrophobicContact CD2-CG 4.5Å; F185-R189 HydrophobicContact CE1-CG 3.72Å; F185-R189 HydrophobicContact CE2-CG 4Å; F185-R189 HydrophobicContact CZ-CG 3.59Å; F185-R189 WeakPolarHBondContact O-CG 3.33Å; F185-R189 PolarHBondContact O-N 2.95Å
186Q98.4Very high96.7Very high93 Ų9352.3 Ų52.344%0.43526%0.26SS..Hα-helixtrans-61.1-43.4175.6-169.762.353.400111R182 S183 M184 V188 R189 D190R182-Q186 WeakPolarHBondContact O-CB 3.29Å; R182-Q186 PolarHBondContact O-N 2.93Å; S183-Q186 WeakPolarHBondContact O-CB 3.37Å; S183-Q186 PolarHBondContact O-N 3.16Å; S183-Q186 VanDerWaalsContact O-N 3.16Å; M184-Q186 VanDerWaalsContact C-N 3.35Å; Q186-V188 VanDerWaalsContact C-N 3.3Å; Q186-V188 PolarHBondContact O-N 3.35Å; Q186-R189 WeakPolarHBondContact O-CB 3.43Å; Q186-R189 PolarHBondContact O-N 2.86Å; Q186-R189 VanDerWaalsContact O-N 3.12Å; Q186-D190 PolarHBondContact NE2-OD1 3.26Å; Q186-D190 WeakPolarHBondContact O-CB 3.47Å; Q186-D190 PolarHBondContact O-N 3Å
187D98.5Very high96.2Very high50 Ų5050.9 Ų50.927%0.26725%0.253SS..Hα-helixtrans-61-38.7176.2-64-22.9000112.1M64 I67 Y69 S183 M184 F185 D190 A191M64-D187 HydrophobicContact CE-CB 3.88Å; M64-D187 HydrophobicContact SD-CB 4.48Å; I67-D187 HydrophobicContact CD1-CB 4.39Å; Y69-D187 HydrophobicContact CE2-CB 3.99Å; Y69-D187 WeakPolarHBondContact CE2-OD2 3.26Å; Y69-D187 WeakPolarHBondContact OH-CB 3.23Å; Y69-D187 PolarHBondContact OH-OD2 2.87Å; S183-D187 VanDerWaalsContact O-CG 3.27Å; S183-D187 PolarHBondContact O-N 2.88Å; M184-D187 PolarHBondContact O-N 3.1Å; F185-D187 VanDerWaalsContact C-N 3.33Å; F185-D187 PolarHBondContact O-N 3.11Å; D187-D190 PolarHBondContact O-N 2.87Å; D187-A191 VanDerWaalsContact O-CB 3.25Å; D187-A191 WeakPolarHBondContact O-CB 3.44Å; D187-A191 PolarHBondContact O-N 3.2Å
188V98.2Very high95.9Very high0 Ų047.9 Ų47.90%024%0.24CC..Hα-helixtrans-64-43174.5172.80000111.2M64 E148 L151 L155 M184 F185 Q186 A191 M192M64-V188 HydrophobicContact CE-CG2 3.77Å; M64-V188 HydrophobicContact SD-CG2 4.2Å; E148-V188 HydrophobicContact CB-CG1 4.13Å; E148-V188 HydrophobicContact CG-CG1 4.23Å; L151-V188 HydrophobicContact CD2-CG1 4.46Å; L151-V188 HydrophobicContact CD2-CG2 4.49Å; L155-V188 HydrophobicContact CD1-CG2 3.61Å; M184-V188 WeakPolarHBondContact O-CG2 3.34Å; M184-V188 PolarHBondContact O-N 3.08Å; F185-V188 PolarHBondContact O-N 3.35Å; Q186-V188 VanDerWaalsContact C-N 3.3Å; Q186-V188 PolarHBondContact O-N 3.35Å; V188-A191 PolarHBondContact O-N 3.19Å; V188-M192 PolarHBondContact O-N 2.89Å
189R97.1Very high95.4Very high40 Ų4043.5 Ų43.515%0.15123%0.226CC..Hα-helixtrans-63.2-47.3176.1-73.8-56.4-48.2166.66.4111.5E148 F185 Q186 A191 M192 D193E148-R189 WeakPolarHBondContact OE1-CD 3.46Å; E148-R189 IonicContact OE1-CZ 3.7Å; E148-R189 IonicContact OE1-NE 3.73Å; E148-R189 IonicContact OE1-NH1 2.78Å; E148-R189 PolarHBondContact OE1-NH1 3.38Å; E148-R189 IonicContact OE2-NH1 3.29Å; E148-R189 PolarHBondContact OE2-NH1 3.04Å; F185-R189 HydrophobicContact CD1-CG 4.23Å; F185-R189 HydrophobicContact CD2-CG 4.5Å; F185-R189 HydrophobicContact CE1-CG 3.72Å; F185-R189 HydrophobicContact CE2-CG 4Å; F185-R189 HydrophobicContact CZ-CG 3.59Å; F185-R189 WeakPolarHBondContact O-CG 3.33Å; F185-R189 PolarHBondContact O-N 2.95Å; Q186-R189 WeakPolarHBondContact O-CB 3.43Å; Q186-R189 PolarHBondContact O-N 2.86Å; Q186-R189 VanDerWaalsContact O-N 3.12Å; R189-A191 VanDerWaalsContact C-N 3.27Å; R189-A191 PolarHBondContact O-N 2.85Å; R189-M192 WeakPolarHBondContact O-CB 3.32Å; R189-M192 PolarHBondContact O-N 2.91Å; R189-M192 VanDerWaalsContact O-N 3.12Å; R189-D193 IonicContact NH2-OD1 2.68Å; R189-D193 PolarHBondContact NH2-OD1 3.32Å; R189-D193 WeakPolarHBondContact O-CB 3.44Å; R189-D193 VanDerWaalsContact O-CG 3.24Å; R189-D193 PolarHBondContact O-N 3.25Å
190D97.5Very high95.1Very high77 Ų7743.8 Ų43.841%0.41223%0.23SC..Hα-helixtrans-64.8-34179.2-65.8-7.1000111.2Q186 D187 F194Q186-D190 PolarHBondContact NE2-OD1 3.26Å; Q186-D190 WeakPolarHBondContact O-CB 3.47Å; Q186-D190 PolarHBondContact O-N 3Å; D187-D190 PolarHBondContact O-N 2.87Å; D190-F194 VanDerWaalsContact O-CB 3.23Å; D190-F194 WeakPolarHBondContact O-CB 3.46Å; D190-F194 PolarHBondContact O-N 3.37Å
191A97.4Very high94.8Very high2 Ų242.7 Ų42.72%0.01722%0.221CC..Hα-helixtrans-65.8-42.2172.400000112L60 R63 M64 D187 V188 R189 I195L60-A191 HydrophobicContact CD2-CB 4.2Å; R63-A191 HydrophobicContact CB-CB 4.27Å; R63-A191 HydrophobicContact CG-CB 3.62Å; M64-A191 HydrophobicContact SD-CB 3.77Å; D187-A191 VanDerWaalsContact O-CB 3.25Å; D187-A191 WeakPolarHBondContact O-CB 3.44Å; D187-A191 PolarHBondContact O-N 3.2Å; V188-A191 PolarHBondContact O-N 3.19Å; R189-A191 VanDerWaalsContact C-N 3.27Å; R189-A191 PolarHBondContact O-N 2.85Å; A191-I195 WeakPolarHBondContact O-CD1 3.44Å; A191-I195 VanDerWaalsContact O-CG1 3.26Å; A191-I195 WeakPolarHBondContact O-CG1 3.42Å; A191-I195 PolarHBondContact O-N 3.31Å
192M94.6Very high94.5Very high10 Ų1044.1 Ų44.15%0.04923%0.228CC..Hα-helixtrans-65.4-47.1175.5-175.853.688.500111.6L60 E148 V188 R189 F194 I195 H196L60-M192 HydrophobicContact CD1-CE 3.54Å; L60-M192 HydrophobicContact CD2-CB 3.75Å; L60-M192 HydrophobicContact CD2-CE 3.84Å; L60-M192 HydrophobicContact CD2-CG 4.49Å; L60-M192 HydrophobicContact CD2-SD 4.14Å; L60-M192 HydrophobicContact CG-CE 3.88Å; E148-M192 HydrophobicContact CG-CB 4.41Å; E148-M192 HydrophobicContact CG-CE 3.56Å; E148-M192 HydrophobicContact CG-CG 4.42Å; E148-M192 WeakPolarHBondContact OE1-CB 3.36Å; V188-M192 PolarHBondContact O-N 2.89Å; R189-M192 WeakPolarHBondContact O-CB 3.32Å; R189-M192 PolarHBondContact O-N 2.91Å; R189-M192 VanDerWaalsContact O-N 3.12Å; M192-F194 VanDerWaalsContact C-N 3.3Å; M192-F194 PolarHBondContact O-N 3.44Å; M192-I195 PolarHBondContact O-N 2.94Å; M192-I195 VanDerWaalsContact O-N 3.13Å; M192-H196 PolarHBondContact O-CD2 3.45Å; M192-H196 VanDerWaalsContact O-CD2 3.29Å; M192-H196 PolarHBondContact O-N 2.95Å; M192-H196 VanDerWaalsContact SD-CD2 3.59Å; M192-H196 PolarHBondContact SD-NE2 3.5Å
193D92.1Very high94.3Very high62 Ų6245.1 Ų45.133%0.33224%0.236SC..Hα-helixtrans-60.7-42.6178.3-66.2-11.4000109.8R189 I195 H196 D197R189-D193 IonicContact NH2-OD1 2.68Å; R189-D193 PolarHBondContact NH2-OD1 3.32Å; R189-D193 WeakPolarHBondContact O-CB 3.44Å; R189-D193 VanDerWaalsContact O-CG 3.24Å; R189-D193 PolarHBondContact O-N 3.25Å; D193-I195 PolarHBondContact O-N 3.41Å; D193-H196 PolarHBondContact O-N 3.33Å; D193-D197 VanDerWaalsContact O-CB 3.29Å; D193-D197 WeakPolarHBondContact O-CB 3.48Å; D193-D197 VanDerWaalsContact O-CG 3.22Å; D193-D197 PolarHBondContact O-N 3.3Å
194F95Very high94.2Very high84 Ų8446.5 Ų46.537%0.36824%0.238SC..Hα-helixtrans-57.2-46.4172.3177.2-92.3000112.7R63 D190 M192 H196 D197 T198R63-F194 HydrophobicContact CG-CD1 4.24Å; D190-F194 VanDerWaalsContact O-CB 3.23Å; D190-F194 WeakPolarHBondContact O-CB 3.46Å; D190-F194 PolarHBondContact O-N 3.37Å; M192-F194 VanDerWaalsContact C-N 3.3Å; M192-F194 PolarHBondContact O-N 3.44Å; F194-H196 VanDerWaalsContact C-N 3.29Å; F194-H196 PolarHBondContact O-N 3.16Å; F194-D197 PolarHBondContact O-N 2.89Å; F194-T198 HydrophobicContact CD1-CG2 4.16Å; F194-T198 HydrophobicContact CD2-CG2 4.02Å; F194-T198 HydrophobicContact CE1-CG2 3.82Å; F194-T198 HydrophobicContact CE2-CG2 3.66Å; F194-T198 HydrophobicContact CG-CG2 4.27Å; F194-T198 HydrophobicContact CZ-CG2 3.56Å; F194-T198 WeakPolarHBondContact O-CB 3.37Å; F194-T198 WeakPolarHBondContact O-CG2 3.26Å; F194-T198 PolarHBondContact O-N 3.12Å; F194-T198 PolarHBondContact O-OG1 3.39Å
195I93.8Very high94.1Very high6 Ų646.5 Ų46.53%0.03124%0.238CC..Hα-helixtrans-63.7-36-179.9-72.3161.1000111.7L59 L60 R63 A191 M192 D193 T198 G199 T200 L201L59-I195 HydrophobicContact CB-CD1 3.84Å; L59-I195 HydrophobicContact CB-CG1 4.43Å; L59-I195 HydrophobicContact CB-CG2 4.5Å; L59-I195 HydrophobicContact CD1-CG2 4.21Å; L60-I195 HydrophobicContact CB-CD1 4.35Å; L60-I195 HydrophobicContact CD2-CD1 3.76Å; L60-I195 HydrophobicContact CG-CD1 3.97Å; R63-I195 HydrophobicContact CB-CD1 4.3Å; A191-I195 WeakPolarHBondContact O-CD1 3.44Å; A191-I195 VanDerWaalsContact O-CG1 3.26Å; A191-I195 WeakPolarHBondContact O-CG1 3.42Å; A191-I195 PolarHBondContact O-N 3.31Å; M192-I195 PolarHBondContact O-N 2.94Å; M192-I195 VanDerWaalsContact O-N 3.13Å; D193-I195 PolarHBondContact O-N 3.41Å; I195-T198 PolarHBondContact O-OG1 3.41Å; I195-G199 PolarHBondContact O-N 2.88Å; I195-T200 PolarHBondContact O-N 3.43Å; I195-L201 HydrophobicContact CG2-CB 3.63Å
196H87.1Confident94Very high60 Ų6049.6 Ų49.628%0.27825%0.254SS..Hα-helixtrans-72.4-44.1174.7-79.2-65.1000112.1M192 D193 F194 G199M192-H196 PolarHBondContact O-CD2 3.45Å; M192-H196 VanDerWaalsContact O-CD2 3.29Å; M192-H196 PolarHBondContact O-N 2.95Å; M192-H196 VanDerWaalsContact SD-CD2 3.59Å; M192-H196 PolarHBondContact SD-NE2 3.5Å; D193-H196 PolarHBondContact O-N 3.33Å; F194-H196 VanDerWaalsContact C-N 3.29Å; F194-H196 PolarHBondContact O-N 3.16Å; H196-G199 PolarHBondContact O-N 3.5Å; H196-G199 VanDerWaalsContact O-N 3.09Å
197D86.7Confident93.9Very high142 Ų14252.2 Ų52.276%0.75926%0.264SS*.Hα-helixtrans-69.9-38.1-176.8-74.8-12.7000112.6D193 F194 G199D193-D197 VanDerWaalsContact O-CB 3.29Å; D193-D197 WeakPolarHBondContact O-CB 3.48Å; D193-D197 VanDerWaalsContact O-CG 3.22Å; D193-D197 PolarHBondContact O-N 3.3Å; F194-D197 PolarHBondContact O-N 2.89Å; D197-G199 PolarHBondContact O-N 3.35Å
198T89.7Confident93.7Very high66 Ų6653 Ų5341%0.40527%0.268SS..THydrogen-bonded Turntrans-74-12.3171.861.40000112.6F194 I195 T200F194-T198 HydrophobicContact CD1-CG2 4.16Å; F194-T198 HydrophobicContact CD2-CG2 4.02Å; F194-T198 HydrophobicContact CE1-CG2 3.82Å; F194-T198 HydrophobicContact CE2-CG2 3.66Å; F194-T198 HydrophobicContact CG-CG2 4.27Å; F194-T198 HydrophobicContact CZ-CG2 3.56Å; F194-T198 WeakPolarHBondContact O-CB 3.37Å; F194-T198 WeakPolarHBondContact O-CG2 3.26Å; F194-T198 PolarHBondContact O-N 3.12Å; F194-T198 PolarHBondContact O-OG1 3.39Å; I195-T198 PolarHBondContact O-OG1 3.41Å; T198-T200 PolarHBondContact O-N 2.81Å; T198-T200 PolarHBondContact OG1-N 2.87Å; T198-T200 PolarHBondContact OG1-OG1 2.83Å
199G88.4Confident93.6Very high19 Ų1954.2 Ų54.220%0.19627%0.274CS..THydrogen-bonded Turntrans69.811.9-177.100000114.2I195 H196 D197 L201 K202 E203I195-G199 PolarHBondContact O-N 2.88Å; H196-G199 PolarHBondContact O-N 3.5Å; H196-G199 VanDerWaalsContact O-N 3.09Å; D197-G199 PolarHBondContact O-N 3.35Å; G199-L201 VanDerWaalsContact C-N 3.34Å; G199-L201 PolarHBondContact O-N 3.12Å; G199-K202 WeakPolarHBondContact O-CB 3.44Å; G199-K202 PolarHBondContact O-N 3.29Å; G199-K202 VanDerWaalsContact O-N 3.13Å; G199-E203 WeakPolarHBondContact O-CB 3.46Å; G199-E203 PolarHBondContact O-N 3.21Å
200T92.2Very high93.6Very high43 Ų4358.7 Ų58.726%0.26430%0.297SS..Hα-helixtrans-59.9-42.6-175.3-56.80000112.2L59 I195 T198 K202 E203 Q204L59-T200 HydrophobicContact CD1-CG2 4.46Å; L59-T200 HydrophobicContact CD2-CG2 3.96Å; I195-T200 PolarHBondContact O-N 3.43Å; T198-T200 PolarHBondContact O-N 2.81Å; T198-T200 PolarHBondContact OG1-N 2.87Å; T198-T200 PolarHBondContact OG1-OG1 2.83Å; T200-K202 PolarHBondContact O-N 2.99Å; T200-E203 PolarHBondContact O-N 2.84Å; T200-Q204 WeakPolarHBondContact O-CG 3.4Å; T200-Q204 PolarHBondContact O-N 3.49Å
201L92.6Very high93.6Very high6 Ų659 Ų593%0.03129%0.294CS..Hα-helixtrans-61.1-45.6176.3-179.369.5000111.3M55 L59 I195 G199 Q204 T205M55-L201 HydrophobicContact CE-CD1 3.47Å; M55-L201 VanDerWaalsContact CE-CD1 3.47Å; M55-L201 HydrophobicContact CE-CG 4.48Å; L59-L201 HydrophobicContact CD1-CB 4.24Å; L59-L201 HydrophobicContact CD1-CD1 3.9Å; I195-L201 HydrophobicContact CG2-CB 3.63Å; G199-L201 VanDerWaalsContact C-N 3.34Å; G199-L201 PolarHBondContact O-N 3.12Å; L201-Q204 PolarHBondContact O-N 3.13Å; L201-T205 WeakPolarHBondContact O-CB 3.46Å; L201-T205 PolarHBondContact O-N 3.05Å; L201-T205 PolarHBondContact O-OG1 3.42Å
202K92.5Very high93.6Very high37 Ų3760 Ų6016%0.16130%0.298CS..Hα-helixtrans-63.6-43.9179.5-72.6177.4168.6172.10111.6G199 T200 T205 I206 D239 Y242G199-K202 WeakPolarHBondContact O-CB 3.44Å; G199-K202 PolarHBondContact O-N 3.29Å; G199-K202 VanDerWaalsContact O-N 3.13Å; T200-K202 PolarHBondContact O-N 2.99Å; K202-T205 WeakPolarHBondContact O-CB 3.35Å; K202-T205 PolarHBondContact O-N 3.02Å; K202-I206 WeakPolarHBondContact O-CG1 3.47Å; K202-I206 PolarHBondContact O-N 3.42Å; K202-D239 IonicContact NZ-OD2 3.56Å; K202-D239 PolarHBondContact NZ-OD2 2.83Å; K202-Y242 HydrophobicContact CB-CD2 3.44Å; K202-Y242 VanDerWaalsContact CB-CD2 3.44Å; K202-Y242 HydrophobicContact CB-CE2 3.62Å; K202-Y242 HydrophobicContact CB-CG 4.18Å; K202-Y242 HydrophobicContact CD-CD1 4.12Å; K202-Y242 HydrophobicContact CD-CD2 3.85Å; K202-Y242 HydrophobicContact CD-CE2 4.43Å; K202-Y242 HydrophobicContact CD-CG 3.67Å; K202-Y242 HydrophobicContact CG-CD1 4.17Å; K202-Y242 HydrophobicContact CG-CD2 3.48Å; K202-Y242 VanDerWaalsContact CG-CD2 3.48Å; K202-Y242 HydrophobicContact CG-CE1 4.28Å; K202-Y242 HydrophobicContact CG-CE2 3.61Å; K202-Y242 HydrophobicContact CG-CG 3.78Å
203E94.2Very high93.8Very high103 Ų10359.5 Ų59.548%0.48130%0.296SS..Hα-helixtrans-61.6-47.5177.4-168.3-165.8156.200111.5G199 T200 T205 I206 K207G199-E203 WeakPolarHBondContact O-CB 3.46Å; G199-E203 PolarHBondContact O-N 3.21Å; T200-E203 PolarHBondContact O-N 2.84Å; E203-T205 VanDerWaalsContact C-N 3.29Å; E203-T205 PolarHBondContact O-N 3.13Å; E203-I206 PolarHBondContact O-N 3.42Å; E203-K207 WeakPolarHBondContact O-CG 3.47Å; E203-K207 PolarHBondContact O-N 2.95Å; E203-K207 WeakPolarHBondContact OE1-CE 3.32Å; E203-K207 IonicContact OE1-NZ 3.43Å; E203-K207 PolarHBondContact OE1-NZ 2.9Å
204Q95.2Very high94Very high71 Ų7159.4 Ų59.433%0.33230%0.297SS..Hα-helixtrans-63.8-36.1176.7-71.6-163.5-5.600112.5M55 T200 L201 K207M55-Q204 HydrophobicContact SD-CB 3.64Å; T200-Q204 WeakPolarHBondContact O-CG 3.4Å; T200-Q204 PolarHBondContact O-N 3.49Å; L201-Q204 PolarHBondContact O-N 3.13Å; Q204-K207 PolarHBondContact O-N 2.93Å
205T96.1Very high93.9Very high0 Ų059.5 Ų59.50%030%0.297CS..Hα-helixtrans-62.8-49.6175.6-53.60000111.1Y47 Y52 L201 K202 E203 K207 N208 L209 V213Y47-T205 HydrophobicContact CE1-CG2 4.03Å; Y52-T205 HydrophobicContact CE2-CG2 3.92Å; Y52-T205 WeakPolarHBondContact CE2-OG1 3.38Å; L201-T205 WeakPolarHBondContact O-CB 3.46Å; L201-T205 PolarHBondContact O-N 3.05Å; L201-T205 PolarHBondContact O-OG1 3.42Å; K202-T205 WeakPolarHBondContact O-CB 3.35Å; K202-T205 PolarHBondContact O-N 3.02Å; E203-T205 VanDerWaalsContact C-N 3.29Å; E203-T205 PolarHBondContact O-N 3.13Å; T205-K207 VanDerWaalsContact C-N 3.29Å; T205-K207 PolarHBondContact O-N 3.33Å; T205-N208 CarbonylContact O-C 3.57Å; T205-N208 VanDerWaalsContact O-C 3.24Å; T205-N208 PolarHBondContact O-N 3.49Å; T205-N208 VanDerWaalsContact O-N 3.15Å; T205-L209 HydrophobicContact CG2-CD2 4.26Å; T205-L209 PolarHBondContact O-N 3.35Å; T205-V213 HydrophobicContact CG2-CG2 4.23Å
206I96.1Very high93.9Very high70 Ų7061.2 Ų61.236%0.35931%0.307SS..Hα-helixtrans-64.4-34.3-179-68.1167.2000111.6K202 E203 N208 Y242 A245K202-I206 WeakPolarHBondContact O-CG1 3.47Å; K202-I206 PolarHBondContact O-N 3.42Å; E203-I206 PolarHBondContact O-N 3.42Å; I206-N208 PolarHBondContact O-N 3.27Å; I206-Y242 HydrophobicContact CD1-CD2 3.7Å; I206-Y242 HydrophobicContact CD1-CE2 4.2Å; I206-Y242 HydrophobicContact CG1-CD2 4.1Å; I206-Y242 HydrophobicContact CG1-CE2 4.09Å; I206-A245 HydrophobicContact CD1-CB 3.73Å; I206-A245 HydrophobicContact CG1-CB 3.92Å; I206-A245 HydrophobicContact CG2-CB 4.39Å
207K96.3Very high94.2Very high148 Ų14862.3 Ų62.364%0.64332%0.319SS*.Hα-helixtrans-59.4-25.7176.5-77.9173.2-177.5167.40113.3E203 Q204 T205E203-K207 WeakPolarHBondContact O-CG 3.47Å; E203-K207 PolarHBondContact O-N 2.95Å; E203-K207 WeakPolarHBondContact OE1-CE 3.32Å; E203-K207 IonicContact OE1-NZ 3.43Å; E203-K207 PolarHBondContact OE1-NZ 2.9Å; Q204-K207 PolarHBondContact O-N 2.93Å; T205-K207 VanDerWaalsContact C-N 3.29Å; T205-K207 PolarHBondContact O-N 3.33Å
208N96.1Very high94.5Very high68 Ų6858.8 Ų58.836%0.36430%0.301SS..THydrogen-bonded Turntrans-148.967.8178.5-164.7-17.6000112.4T205 I206 E210 K211 Y212T205-N208 CarbonylContact O-C 3.57Å; T205-N208 VanDerWaalsContact O-C 3.24Å; T205-N208 PolarHBondContact O-N 3.49Å; T205-N208 VanDerWaalsContact O-N 3.15Å; I206-N208 PolarHBondContact O-N 3.27Å; N208-E210 PolarHBondContact O-N 2.98Å; N208-K211 HydrophobicContact CB-CB 4.24Å; N208-K211 VanDerWaalsContact CG-CB 3.45Å; N208-K211 PolarHBondContact O-N 2.73Å; N208-K211 VanDerWaalsContact O-N 3.13Å; N208-K211 WeakPolarHBondContact OD1-CB 3.43Å; N208-K211 PolarHBondContact OD1-N 3.46Å; N208-K211 VanDerWaalsContact OD1-N 3.08Å; N208-Y212 HydrophobicContact CB-CD2 4.34Å; N208-Y212 HydrophobicContact CB-CE2 4.23Å; N208-Y212 WeakPolarHBondContact O-CD2 3.27Å; N208-Y212 PolarHBondContact O-N 2.91Å
209L96.2Very high94.8Very high24 Ų2456 Ų5613%0.12628%0.283CS..Hα-helixtrans-59-33.5-179.6-69.2171000113T205 K211 Y212 V213 I246 Y249T205-L209 HydrophobicContact CG2-CD2 4.26Å; T205-L209 PolarHBondContact O-N 3.35Å; L209-K211 VanDerWaalsContact C-N 3.31Å; L209-K211 PolarHBondContact O-N 2.67Å; L209-Y212 PolarHBondContact O-N 3.2Å; L209-V213 HydrophobicContact CD2-CG2 3.93Å; L209-V213 WeakPolarHBondContact O-CB 3.41Å; L209-V213 PolarHBondContact O-N 3.3Å; L209-I246 HydrophobicContact CD2-CD1 3.55Å; L209-Y249 HydrophobicContact CB-CD1 4.29Å; L209-Y249 HydrophobicContact CB-CD2 3.84Å; L209-Y249 HydrophobicContact CB-CE1 4.31Å; L209-Y249 HydrophobicContact CB-CE2 3.86Å; L209-Y249 HydrophobicContact CB-CG 4.06Å; L209-Y249 HydrophobicContact CD1-CD2 3.93Å; L209-Y249 HydrophobicContact CD1-CG 3.86Å; L209-Y249 HydrophobicContact CG-CG 4.5Å
210E95.7Very high95.1Very high135 Ų13555.8 Ų55.863%0.63128%0.278SS*.Hα-helixtrans-66.6-32.6178.6-70.9141.1-173.300112.8K48 N208 Y249K48-E210 WeakPolarHBondContact CE-O 3.46Å; K48-E210 PolarHBondContact NZ-O 2.8Å; N208-E210 PolarHBondContact O-N 2.98Å; E210-Y249 HydrophobicContact CG-CE2 4.07Å
211K97.2Very high95.3Very high82 Ų8256.5 Ų56.536%0.35728%0.282SS..Hα-helixtrans-73.4-36.1173.4-176.9-179.9174.2-161.40111.9K48 N208 L209K48-K211 WeakPolarHBondContact CD-O 3.49Å; N208-K211 HydrophobicContact CB-CB 4.24Å; N208-K211 VanDerWaalsContact CG-CB 3.45Å; N208-K211 PolarHBondContact O-N 2.73Å; N208-K211 VanDerWaalsContact O-N 3.13Å; N208-K211 WeakPolarHBondContact OD1-CB 3.43Å; N208-K211 PolarHBondContact OD1-N 3.46Å; N208-K211 VanDerWaalsContact OD1-N 3.08Å; L209-K211 VanDerWaalsContact C-N 3.31Å; L209-K211 PolarHBondContact O-N 2.67Å
212Y97.9Very high95.5Very high23 Ų2356.2 Ų56.29%0.0928%0.281CS..Hα-helixtrans-105.9-21.9-165.6-65.8-54.9000115.6Y47 K48 D51 Y52 M55 N208 L209Y47-Y212 CarbonylContact C-O 3.59Å; Y47-Y212 WeakPolarHBondContact CA-O 3.49Å; K48-Y212 PolarHBondContact N-O 3.14Å; D51-Y212 HydrophobicContact CB-CD1 4.26Å; D51-Y212 HydrophobicContact CB-CE1 4.26Å; Y52-Y212 HydrophobicContact CD2-CD1 4.2Å; Y52-Y212 HydrophobicContact CD2-CG 4.29Å; M55-Y212 HydrophobicContact CB-CE1 4.13Å; M55-Y212 HydrophobicContact CE-CD1 4.27Å; M55-Y212 HydrophobicContact CE-CD2 4.5Å; M55-Y212 HydrophobicContact CE-CE1 4.22Å; M55-Y212 HydrophobicContact CE-CE2 4.42Å; M55-Y212 HydrophobicContact CE-CG 4.42Å; M55-Y212 HydrophobicContact SD-CD2 4.33Å; M55-Y212 HydrophobicContact SD-CE1 3.94Å; M55-Y212 HydrophobicContact SD-CE2 3.71Å; N208-Y212 HydrophobicContact CB-CD2 4.34Å; N208-Y212 HydrophobicContact CB-CE2 4.23Å; N208-Y212 WeakPolarHBondContact O-CD2 3.27Å; N208-Y212 PolarHBondContact O-N 2.91Å; L209-Y212 PolarHBondContact O-N 3.2Å
213V97.9Very high95.8Very high0 Ų054.5 Ų54.50%027%0.273CS..BIsolated β-bridgetrans-120.8129.6-174-172.80000110Y47 K48 T205 L209 K215 I246 Y249 L250Y47-V213 HydrophobicContact CD1-CG2 3.94Å; Y47-V213 HydrophobicContact CE1-CG2 3.88Å; K48-V213 WeakPolarHBondContact CE-O 3.09Å; T205-V213 HydrophobicContact CG2-CG2 4.23Å; L209-V213 HydrophobicContact CD2-CG2 3.93Å; L209-V213 WeakPolarHBondContact O-CB 3.41Å; L209-V213 PolarHBondContact O-N 3.3Å; V213-K215 PolarHBondContact O-N 2.99Å; V213-I246 HydrophobicContact CG2-CD1 4.07Å; V213-Y249 HydrophobicContact CB-CD1 4.43Å; V213-Y249 HydrophobicContact CB-CE1 4.09Å; V213-Y249 HydrophobicContact CG1-CD1 4.31Å; V213-Y249 HydrophobicContact CG1-CE1 4.22Å; V213-L250 HydrophobicContact CG1-CD2 4.08Å
214V96.3Very high95.8Very high61 Ų6152 Ų5237%0.3727%0.265SS..  trans-70.8126.4171.7-1780000108.5M46 K48M46-V214 HydrophobicContact CB-CB 4.07Å; M46-V214 HydrophobicContact CB-CG2 4.14Å; M46-V214 HydrophobicContact CG-CG2 4.26Å; M46-V214 PolarHBondContact O-N 3.01Å; K48-V214 HydrophobicContact CG-CG2 3.71Å
215K93.8Very high95.9Very high85 Ų8554.2 Ų54.237%0.3727%0.271SS..  trans-103.9107175.9-170175.3-179.3176.90109.7V213 Y249 S253V213-K215 PolarHBondContact O-N 2.99Å; K215-Y249 HydrophobicContact CB-CE1 3.81Å; K215-Y249 HydrophobicContact CD-CE1 4.04Å; K215-Y249 HydrophobicContact CD-CE2 4.14Å; K215-Y249 WeakPolarHBondContact CE-O 3.45Å; K215-Y249 HydrophobicContact CG-CE1 4.12Å; K215-S253 VanDerWaalsContact CE-CB 3.49Å
216D93.3Very high96Very high43 Ų4354.2 Ų54.223%0.2327%0.271CS..  trans-105.9116.2177.6-171.9-22.6000110.5N218 I219D216-N218 PolarHBondContact O-N 3.35Å; D216-N218 VanDerWaalsContact O-N 3.1Å; D216-N218 WeakPolarHBondContact OD1-CB 3.42Å; D216-N218 PolarHBondContact OD1-N 2.99Å; D216-N218 PolarHBondContact OD1-ND2 2.75Å; D216-I219 HydrophobicContact CB-CD1 4.11Å; D216-I219 HydrophobicContact CB-CG1 4.08Å; D216-I219 PolarHBondContact O-N 3.43Å
217P92.9Very high96Very high83 Ų8353.6 Ų53.654%0.53927%0.265SS..THydrogen-bonded Turntrans-66.5-9.1-18030.1-36.7000113.7P220P217-P220 WeakPolarHBondContact O-CD 3.25Å
218N94.6Very high96Very high68 Ų6853.7 Ų53.736%0.36427%0.268SS..Hα-helixtrans-82.9-15.1176.7-60.7-61.4000113.3D216 V221 L222 I451 L454D216-N218 PolarHBondContact O-N 3.35Å; D216-N218 VanDerWaalsContact O-N 3.1Å; D216-N218 WeakPolarHBondContact OD1-CB 3.42Å; D216-N218 PolarHBondContact OD1-N 2.99Å; D216-N218 PolarHBondContact OD1-ND2 2.75Å; N218-V221 WeakPolarHBondContact O-CB 3.4Å; N218-V221 PolarHBondContact O-N 2.76Å; N218-L222 PolarHBondContact O-N 3.43Å; N218-I451 HydrophobicContact CB-CD1 4.48Å; N218-I451 HydrophobicContact CB-CG2 3.83Å; N218-L454 HydrophobicContact CB-CD2 3.96Å
219I95.9Very high96.1Very high7 Ų754.5 Ų54.54%0.03628%0.275CS..Hα-helixtrans-60-52.2178.4-58.1166000110.9L44 D216 V221 L222 L223 L250 L251 I451L44-I219 HydrophobicContact CD2-CG2 3.99Å; L44-I219 WeakPolarHBondContact O-CD1 3.29Å; D216-I219 HydrophobicContact CB-CD1 4.11Å; D216-I219 HydrophobicContact CB-CG1 4.08Å; D216-I219 PolarHBondContact O-N 3.43Å; I219-V221 PolarHBondContact O-N 3.34Å; I219-L222 PolarHBondContact O-N 3.18Å; I219-L223 HydrophobicContact CG2-CD1 4.02Å; I219-L223 HydrophobicContact CG2-CG 4.36Å; I219-L223 WeakPolarHBondContact O-CG 3.41Å; I219-L223 PolarHBondContact O-N 2.74Å; I219-L250 HydrophobicContact CD1-CD2 4.17Å; I219-L251 HydrophobicContact CB-CD2 4.32Å; I219-L251 HydrophobicContact CG2-CD2 3.72Å; I219-I451 HydrophobicContact CB-CD1 4.13Å; I219-I451 HydrophobicContact CG1-CD1 3.49Å; I219-I451 VanDerWaalsContact CG1-CD1 3.49Å; I219-I451 HydrophobicContact CG1-CG1 4.26Å
220P94.9Very high96.1Very high15 Ų1554 Ų5410%0.09727%0.274CS..Hα-helixtrans-59.9-33.5176.7-21.132000113.1P217 T224 L251 F267P217-P220 WeakPolarHBondContact O-CD 3.25Å; P220-T224 VanDerWaalsContact O-CB 3.31Å; P220-T224 WeakPolarHBondContact O-CB 3.39Å; P220-T224 PolarHBondContact O-N 2.82Å; P220-T224 PolarHBondContact O-OG1 2.81Å; P220-L251 HydrophobicContact CB-CD2 4.31Å; P220-L251 HydrophobicContact CG-CD2 3.79Å; P220-F267 HydrophobicContact CB-CE1 3.88Å; P220-F267 HydrophobicContact CB-CZ 3.98Å
221V95.6Very high96.2Very high57 Ų5751.4 Ų51.435%0.34526%0.261SS..Hα-helixtrans-67.3-48.4179.2-178.50000110.4N218 I219 T224 R225 L454N218-V221 WeakPolarHBondContact O-CB 3.4Å; N218-V221 PolarHBondContact O-N 2.76Å; I219-V221 PolarHBondContact O-N 3.34Å; V221-T224 PolarHBondContact O-N 3.22Å; V221-R225 WeakPolarHBondContact O-CB 3.46Å; V221-R225 WeakPolarHBondContact O-CG 3.47Å; V221-R225 PolarHBondContact O-N 2.88Å; V221-L454 HydrophobicContact CG1-CD1 4.15Å; V221-L454 HydrophobicContact CG1-CD2 4.47Å
222L97.1Very high96.3Very high1 Ų147.5 Ų47.51%0.00524%0.244CC..Hα-helixtrans-58.5-51.9176.9176.263.9000110.9N218 I219 T224 R225 I226 I451 L453 L454N218-L222 PolarHBondContact O-N 3.43Å; I219-L222 PolarHBondContact O-N 3.18Å; L222-T224 VanDerWaalsContact C-N 3.31Å; L222-T224 PolarHBondContact O-N 3.12Å; L222-R225 PolarHBondContact O-N 3.01Å; L222-I226 HydrophobicContact CD1-CD1 3.87Å; L222-I226 HydrophobicContact CD1-CG1 4.17Å; L222-I226 HydrophobicContact CG-CD1 3.84Å; L222-I226 HydrophobicContact CG-CG1 4.49Å; L222-I226 WeakPolarHBondContact O-CG1 3.4Å; L222-I226 PolarHBondContact O-N 3.12Å; L222-I451 HydrophobicContact CD2-CD1 4.06Å; L222-L453 HydrophobicContact CD1-CB 4.09Å; L222-L454 HydrophobicContact CD1-CB 4.35Å; L222-L454 HydrophobicContact CD1-CD1 4.46Å
223L97.5Very high96.3Very high0 Ų046.4 Ų46.40%024%0.24CC..Hα-helixtrans-61.7-39.2-179.1-64.7178.8000112F38 I219 I226 K227 I232 L251 F267 F268F38-L223 HydrophobicContact CD2-CD2 4.25Å; F38-L223 HydrophobicContact CE2-CD2 3.75Å; F38-L223 HydrophobicContact CZ-CD2 3.91Å; I219-L223 HydrophobicContact CG2-CD1 4.02Å; I219-L223 HydrophobicContact CG2-CG 4.36Å; I219-L223 WeakPolarHBondContact O-CG 3.41Å; I219-L223 PolarHBondContact O-N 2.74Å; L223-I226 PolarHBondContact O-N 3.29Å; L223-K227 WeakPolarHBondContact O-CB 3.37Å; L223-K227 PolarHBondContact O-N 2.99Å; L223-I232 HydrophobicContact CB-CD1 4.39Å; L223-I232 HydrophobicContact CD2-CD1 4.34Å; L223-I232 HydrophobicContact CD2-CG2 4.36Å; L223-I232 WeakPolarHBondContact O-CD1 3.41Å; L223-L251 HydrophobicContact CD1-CD1 3.87Å; L223-L251 HydrophobicContact CD1-CD2 3.94Å; L223-F267 HydrophobicContact CB-CB 4.35Å; L223-F267 HydrophobicContact CB-CD1 3.81Å; L223-F267 HydrophobicContact CB-CG 4.5Å; L223-F267 HydrophobicContact CD1-CB 4.17Å; L223-F267 HydrophobicContact CD1-CD1 4.42Å; L223-F267 HydrophobicContact CD1-CG 4.49Å; L223-F268 HydrophobicContact CD1-CE2 4.43Å; L223-F268 HydrophobicContact CD1-CZ 3.88Å
224T96.2Very high96.3Very high51 Ų5146.4 Ų46.431%0.31324%0.24SC..Hα-helixtrans-63.6-46.1176.4-58.40000111.4P220 V221 L222 I226 K227 E228 F267P220-T224 VanDerWaalsContact O-CB 3.31Å; P220-T224 WeakPolarHBondContact O-CB 3.39Å; P220-T224 PolarHBondContact O-N 2.82Å; P220-T224 PolarHBondContact O-OG1 2.81Å; V221-T224 PolarHBondContact O-N 3.22Å; L222-T224 VanDerWaalsContact C-N 3.31Å; L222-T224 PolarHBondContact O-N 3.12Å; T224-I226 PolarHBondContact O-N 3.23Å; T224-K227 PolarHBondContact O-N 2.88Å; T224-E228 PolarHBondContact O-N 3.49Å; T224-F267 WeakPolarHBondContact OG1-CE1 3.16Å
225R97.3Very high96.4Very high118 Ų11843.5 Ų43.545%0.44522%0.222SC..Hα-helixtrans-64.8-38.8179.3-75.4-175.8177.9-175.1-0.1112.7V221 L222 K227 E228 L454 F458V221-R225 WeakPolarHBondContact O-CB 3.46Å; V221-R225 WeakPolarHBondContact O-CG 3.47Å; V221-R225 PolarHBondContact O-N 2.88Å; L222-R225 PolarHBondContact O-N 3.01Å; R225-K227 VanDerWaalsContact C-N 3.32Å; R225-E228 PolarHBondContact O-N 3.48Å; R225-L454 VanDerWaalsContact NH1-CD1 3.28Å; R225-F458 HydrophobicContact CB-CE2 3.81Å; R225-F458 HydrophobicContact CB-CZ 4.01Å; R225-F458 VanDerWaalsContact O-CE2 3.26Å; R225-F458 WeakPolarHBondContact O-CE2 3.49Å
226I97.9Very high96.6Very high0 Ų039.4 Ų39.40%020%0.204CC..Hα-helixtrans-63.1-43.3174.2-67.9169.6000109.9Y36 F38 L222 L223 T224 E228 V229 A230 I232 F458Y36-I226 HydrophobicContact CD1-CD1 4.02Å; Y36-I226 HydrophobicContact CD1-CG2 4.31Å; Y36-I226 HydrophobicContact CD2-CG2 3.33Å; Y36-I226 HydrophobicContact CE1-CD1 4.48Å; Y36-I226 HydrophobicContact CE2-CG2 3.89Å; Y36-I226 HydrophobicContact CG-CD1 4.23Å; Y36-I226 HydrophobicContact CG-CG2 3.59Å; F38-I226 HydrophobicContact CE2-CD1 4.27Å; F38-I226 HydrophobicContact CZ-CD1 3.89Å; L222-I226 HydrophobicContact CD1-CD1 3.87Å; L222-I226 HydrophobicContact CD1-CG1 4.17Å; L222-I226 HydrophobicContact CG-CD1 3.84Å; L222-I226 HydrophobicContact CG-CG1 4.49Å; L222-I226 WeakPolarHBondContact O-CG1 3.4Å; L222-I226 PolarHBondContact O-N 3.12Å; L223-I226 PolarHBondContact O-N 3.29Å; T224-I226 PolarHBondContact O-N 3.23Å; I226-E228 PolarHBondContact O-N 3.19Å; I226-E228 VanDerWaalsContact O-N 3.17Å; I226-V229 VanDerWaalsContact O-CG2 3.28Å; I226-V229 WeakPolarHBondContact O-CG2 3.43Å; I226-V229 PolarHBondContact O-N 3.37Å; I226-A230 HydrophobicContact CG2-CB 4.3Å; I226-A230 PolarHBondContact O-N 2.97Å; I226-I232 HydrophobicContact CB-CD1 3.69Å; I226-I232 HydrophobicContact CB-CG1 4.27Å; I226-I232 HydrophobicContact CG2-CD1 3.58Å; I226-I232 HydrophobicContact CG2-CG1 3.58Å; I226-F458 HydrophobicContact CB-CZ 4.26Å; I226-F458 HydrophobicContact CG1-CE1 3.6Å; I226-F458 HydrophobicContact CG1-CZ 3.54Å
227K95.8Very high96.7Very high57 Ų5740.8 Ų40.825%0.24821%0.212CC..Hα-helixtrans-64.7-21.1-176.6-167.5160.4-171.8148.20113.7L223 T224 R225 V229 A230 I232 A266 F268 D269L223-K227 WeakPolarHBondContact O-CB 3.37Å; L223-K227 PolarHBondContact O-N 2.99Å; T224-K227 PolarHBondContact O-N 2.88Å; R225-K227 VanDerWaalsContact C-N 3.32Å; K227-V229 VanDerWaalsContact C-N 3.27Å; K227-A230 WeakPolarHBondContact CA-O 3.38Å; K227-I232 HydrophobicContact CB-CD1 3.9Å; K227-I232 HydrophobicContact CB-CG1 4.49Å; K227-A266 PolarHBondContact NZ-O 3.5Å; K227-F268 PolarHBondContact NZ-O 3.18Å; K227-D269 WeakPolarHBondContact CE-OD1 3.29Å; K227-D269 IonicContact NZ-OD1 2.68Å; K227-D269 PolarHBondContact NZ-OD1 2.57Å
228E96.6Very high96.8Very high150 Ų15037.2 Ų37.270%0.70119%0.188SC*.THydrogen-bonded Turntrans-70.3-23.3173.1-69.3169.5-175.400112.8T224 R225 I226T224-E228 PolarHBondContact O-N 3.49Å; R225-E228 PolarHBondContact O-N 3.48Å; I226-E228 PolarHBondContact O-N 3.19Å; I226-E228 VanDerWaalsContact O-N 3.17Å
229V97Very high96.8Very high84 Ų8436.1 Ų36.151%0.50918%0.183SC..THydrogen-bonded Turntrans-122.6-18.8-172.6-59.80000114.5I226 K227 F458I226-V229 VanDerWaalsContact O-CG2 3.28Å; I226-V229 WeakPolarHBondContact O-CG2 3.43Å; I226-V229 PolarHBondContact O-N 3.37Å; K227-V229 VanDerWaalsContact C-N 3.27Å; V229-F458 HydrophobicContact CG1-CD2 4.23Å; V229-F458 HydrophobicContact CG2-CB 4.16Å; V229-F458 HydrophobicContact CG2-CD1 4.27Å; V229-F458 HydrophobicContact CG2-CD2 3.7Å; V229-F458 HydrophobicContact CG2-CE2 4.1Å; V229-F458 HydrophobicContact CG2-CG 3.8Å
230A97.6Very high96.8Very high13 Ų1336 Ų3611%0.10718%0.182CC..SBendtrans-153.4161.6-17300000112.1K34 Y36 I226 K227K34-A230 WeakPolarHBondContact O-CB 3.12Å; Y36-A230 HydrophobicContact CD2-CB 3.68Å; Y36-A230 HydrophobicContact CE2-CB 3.66Å; I226-A230 HydrophobicContact CG2-CB 4.3Å; I226-A230 PolarHBondContact O-N 2.97Å; K227-A230 WeakPolarHBondContact CA-O 3.38Å
231K97.7Very high96.9Very high81 Ų8139.5 Ų39.535%0.35220%0.2SC..EExtended strand (participates in β ladder)trans-73.7151.6171.8-64177.3-173175.80110.5K34 C35 Y36 D269 L324K34-K231 PolarHBondContact O-N 2.88Å; C35-K231 CarbonylContact C-O 3.48Å; C35-K231 VanDerWaalsContact CA-O 3.27Å; C35-K231 WeakPolarHBondContact CA-O 3.37Å; C35-K231 HydrophobicContact CB-CB 4.47Å; Y36-K231 PolarHBondContact N-O 2.74Å; K231-D269 VanDerWaalsContact CA-OD2 3.26Å; K231-D269 WeakPolarHBondContact CA-OD2 3.43Å; K231-L324 HydrophobicContact CD-CB 4.42Å; K231-L324 HydrophobicContact CD-CD2 4.21Å; K231-L324 WeakPolarHBondContact CD-O 3.46Å; K231-L324 PolarHBondContact NZ-O 3.16Å
232I97.9Very high96.9Very high0 Ų037 Ų370%018%0.184CC..EExtended strand (participates in β ladder)trans-126.4136.4176.2-50.9-176.9000110.4Y36 F38 L223 I226 K227 F268 D269 L270Y36-I232 CarbonylContact O-C 3.56Å; Y36-I232 VanDerWaalsContact O-CA 3.3Å; Y36-I232 WeakPolarHBondContact O-CA 3.33Å; F38-I232 HydrophobicContact CD2-CG2 3.92Å; F38-I232 HydrophobicContact CE2-CG2 3.93Å; L223-I232 HydrophobicContact CB-CD1 4.39Å; L223-I232 HydrophobicContact CD2-CD1 4.34Å; L223-I232 HydrophobicContact CD2-CG2 4.36Å; L223-I232 WeakPolarHBondContact O-CD1 3.41Å; I226-I232 HydrophobicContact CB-CD1 3.69Å; I226-I232 HydrophobicContact CB-CG1 4.27Å; I226-I232 HydrophobicContact CG2-CD1 3.58Å; I226-I232 HydrophobicContact CG2-CG1 3.58Å; K227-I232 HydrophobicContact CB-CD1 3.9Å; K227-I232 HydrophobicContact CB-CG1 4.49Å; I232-F268 HydrophobicContact CB-CD1 4.5Å; I232-F268 HydrophobicContact CG2-CD1 3.65Å; I232-F268 HydrophobicContact CG2-CE1 3.91Å; I232-D269 PolarHBondContact N-OD2 2.66Å; I232-D269 PolarHBondContact O-N 3.24Å; I232-L270 PolarHBondContact O-N 2.96Å
233F98Very high96.9Very high0 Ų037 Ų370%018%0.184CC..EExtended strand (participates in β ladder)trans-130.5153.5167.672-86000113.7C35 Y36 G37 F38 A235 L270 V320 L324 I331 Y333 W351C35-F233 WeakPolarHBondContact SG-CD1 3.47Å; Y36-F233 PolarHBondContact O-N 2.71Å; G37-F233 CarbonylContact C-O 3.47Å; G37-F233 WeakPolarHBondContact CA-O 3.46Å; F38-F233 PolarHBondContact N-O 2.83Å; F233-A235 HydrophobicContact CD2-CB 3.87Å; F233-A235 HydrophobicContact CE2-CB 3.76Å; F233-L270 CarbonylContact C-O 3.43Å; F233-L270 WeakPolarHBondContact CA-O 3.48Å; F233-L270 HydrophobicContact CB-CB 3.85Å; F233-L270 HydrophobicContact CB-CD2 4.42Å; F233-L270 WeakPolarHBondContact CB-O 3.48Å; F233-V320 HydrophobicContact CD1-CG1 4.28Å; F233-V320 HydrophobicContact CD2-CG1 4.02Å; F233-V320 HydrophobicContact CE1-CG1 4.26Å; F233-V320 HydrophobicContact CE2-CG1 4Å; F233-V320 HydrophobicContact CG-CG1 4.15Å; F233-V320 HydrophobicContact CZ-CG1 4.11Å; F233-L324 HydrophobicContact CB-CD1 3.87Å; F233-L324 HydrophobicContact CD1-CD1 3.72Å; F233-L324 HydrophobicContact CG-CD1 4.02Å; F233-I331 HydrophobicContact CE1-CG2 3.9Å; F233-I331 HydrophobicContact CZ-CG2 4.14Å; F233-Y333 HydrophobicContact CE2-CD2 4Å; F233-Y333 AromaticContact CE2-CE2 3.85Å; F233-Y333 HydrophobicContact CE2-CE2 3.85Å; F233-Y333 AromaticContact CZ-CD2 3.84Å; F233-Y333 HydrophobicContact CZ-CD2 3.84Å; F233-Y333 HydrophobicContact CZ-CE2 4.19Å; F233-W351 HydrophobicContact CE2-CH2 4.24Å; F233-W351 HydrophobicContact CE2-CZ3 4.32Å; F233-W351 AromaticContact CZ-CH2 3.66Å; F233-W351 HydrophobicContact CZ-CH2 3.66Å; F233-W351 AromaticContact CZ-CZ3 3.7Å; F233-W351 HydrophobicContact CZ-CZ3 3.7Å
234L98.6Very high96.8Very high0 Ų038.4 Ų38.40%019%0.191CC..EExtended strand (participates in β ladder)trans-106.2128.7168.2-173.769.1000108.5F38 M40 L44 T243 M247 W264 F268 L270 V271 V272F38-L234 HydrophobicContact CB-CD1 4.28Å; M40-L234 HydrophobicContact CB-CD1 4.22Å; L44-L234 HydrophobicContact CD1-CD1 3.94Å; L234-T243 HydrophobicContact CD2-CG2 3.79Å; L234-M247 HydrophobicContact CD2-CG 4.44Å; L234-W264 HydrophobicContact CD2-CH2 4.4Å; L234-W264 HydrophobicContact CD2-CZ3 4Å; L234-F268 HydrophobicContact CB-CD1 3.83Å; L234-F268 HydrophobicContact CB-CE1 3.91Å; L234-F268 HydrophobicContact CB-CG 4.35Å; L234-F268 HydrophobicContact CB-CZ 4.49Å; L234-F268 HydrophobicContact CD1-CE1 4.4Å; L234-L270 PolarHBondContact N-O 3.44Å; L234-V271 HydrophobicContact CB-CG1 4.4Å; L234-V271 HydrophobicContact CD2-CG1 4.23Å; L234-V272 PolarHBondContact O-N 3.01Å
235A98.1Very high96.8Very high0 Ų037.1 Ų37.10%019%0.185CC..EExtended strand (participates in β ladder)trans-133.998.8174.800000109.1F38 F233 V272 T275 K277 F280 Y333F38-A235 PolarHBondContact O-N 3.33Å; F233-A235 HydrophobicContact CD2-CB 3.87Å; F233-A235 HydrophobicContact CE2-CB 3.76Å; A235-V272 WeakPolarHBondContact CA-O 3.45Å; A235-T275 HydrophobicContact CB-CG2 4.13Å; A235-K277 PolarHBondContact O-NZ 2.86Å; A235-F280 HydrophobicContact CB-CE1 4.39Å; A235-F280 HydrophobicContact CB-CZ 4.47Å; A235-Y333 HydrophobicContact CB-CE2 4.15Å; A235-Y333 PolarHBondContact O-OH 2.92Å
236T97.9Very high96.8Very high0 Ų031.5 Ų31.50%016%0.164CC..  trans-123.2151-171.7-172.80000112.7D39 M40 S238 T243 V272 V273 D274 T275D39-T236 WeakPolarHBondContact OD1-CA 3.48Å; D39-T236 PolarHBondContact OD1-OG1 3.2Å; M40-T236 HydrophobicContact CB-CG2 4.43Å; T236-S238 VanDerWaalsContact C-N 3.29Å; T236-S238 PolarHBondContact OG1-N 3.1Å; T236-T243 HydrophobicContact CG2-CG2 4.4Å; T236-V272 PolarHBondContact N-O 3.47Å; T236-V273 HydrophobicContact CG2-CB 4.5Å; T236-V273 HydrophobicContact CG2-CG1 4.12Å; T236-V273 CarbonylContact O-C 3.24Å; T236-D274 PolarHBondContact O-N 3.37Å; T236-T275 WeakPolarHBondContact O-CG2 3.45Å; T236-T275 PolarHBondContact O-N 3.18Å; T236-T275 PolarHBondContact O-OG1 3.06Å
237N95.9Very high96.8Very high72 Ų7231.6 Ų31.639%0.38516%0.164SC..SBendtrans-77.2-18.7173.2-81.3-5000112.5T275 R276 K277N237-T275 PolarHBondContact N-OG1 3.02Å; N237-T275 PolarHBondContact OD1-OG1 3.45Å; N237-R276 WeakPolarHBondContact OD1-CA 3.43Å; N237-R276 PolarHBondContact OD1-N 2.88Å; N237-K277 PolarHBondContact ND2-O 2.94Å; N237-K277 WeakPolarHBondContact OD1-CB 3.26Å; N237-K277 WeakPolarHBondContact OD1-CE 3.41Å; N237-K277 PolarHBondContact OD1-N 3.22Å
238S95Very high96.8Very high7 Ų732.7 Ų32.75%0.04917%0.169CC..SBendtrans-67.3152.7177.6-83.30000112.2D41 T236 Y242 V273 D274D41-S238 PolarHBondContact OD2-OG 2.83Å; T236-S238 VanDerWaalsContact C-N 3.29Å; T236-S238 PolarHBondContact OG1-N 3.1Å; S238-Y242 WeakPolarHBondContact OG-CD1 3.45Å; S238-V273 WeakPolarHBondContact O-CB 3.25Å; S238-D274 PolarHBondContact O-N 3.42Å
239D94.8Very high96.7Very high46 Ų4626.8 Ų26.825%0.24614%0.141CC..  trans-76.4164.1174.567.482.3000111.4K202 N241 Y242 T243 D274K202-D239 IonicContact NZ-OD2 3.56Å; K202-D239 PolarHBondContact NZ-OD2 2.83Å; D239-N241 PolarHBondContact O-N 3.34Å; D239-N241 PolarHBondContact OD1-N 3.31Å; D239-Y242 PolarHBondContact O-N 2.85Å; D239-Y242 PolarHBondContact OD1-N 2.88Å; D239-T243 WeakPolarHBondContact O-CB 3.35Å; D239-T243 PolarHBondContact O-N 2.83Å; D239-T243 PolarHBondContact O-OG1 3.25Å; D239-T243 VanDerWaalsContact O-OG1 3.06Å; D239-D274 WeakPolarHBondContact CA-OD1 3.48Å
240Y96.2Very high96.6Very high4 Ų423 Ų232%0.01612%0.118CC..Hα-helixtrans-59.4-43.5-176.2177.5-105.5000114.5Y242 T243 E244 W264 V290 T292 V311Y240-Y242 VanDerWaalsContact C-N 3.33Å; Y240-Y242 PolarHBondContact O-N 3.32Å; Y240-T243 PolarHBondContact O-N 3.12Å; Y240-E244 HydrophobicContact CE1-CB 4.37Å; Y240-E244 WeakPolarHBondContact CE1-OE2 3.39Å; Y240-E244 HydrophobicContact CE2-CB 4.38Å; Y240-E244 VanDerWaalsContact O-CB 3.29Å; Y240-E244 WeakPolarHBondContact O-CB 3.29Å; Y240-E244 PolarHBondContact O-N 3.24Å; Y240-E244 VanDerWaalsContact OH-CD 3.31Å; Y240-E244 PolarHBondContact OH-OE1 3.42Å; Y240-E244 PolarHBondContact OH-OE2 2.78Å; Y240-W264 HydrophobicContact CE2-CZ2 4.31Å; Y240-V290 HydrophobicContact CD1-CG1 3.85Å; Y240-V290 HydrophobicContact CD2-CG1 4.17Å; Y240-V290 HydrophobicContact CE1-CG1 4.47Å; Y240-V290 HydrophobicContact CG-CG1 3.66Å; Y240-T292 HydrophobicContact CE2-CG2 4.14Å; Y240-T292 WeakPolarHBondContact OH-CB 3.48Å; Y240-V311 HydrophobicContact CD2-CB 4.37Å; Y240-V311 HydrophobicContact CD2-CG1 3.8Å; Y240-V311 HydrophobicContact CD2-CG2 4.36Å; Y240-V311 HydrophobicContact CE2-CB 4.32Å; Y240-V311 HydrophobicContact CE2-CG1 4.19Å; Y240-V311 HydrophobicContact CE2-CG2 3.89Å
241N95.3Very high96.5Very high88 Ų8822.8 Ų22.847%0.47112%0.115SC..Hα-helixtrans-65.9-42.3-173.9-69.4-31.5000110.6D239 A245 G295D239-N241 PolarHBondContact O-N 3.34Å; D239-N241 PolarHBondContact OD1-N 3.31Å; N241-A245 PolarHBondContact O-N 2.83Å; N241-A245 VanDerWaalsContact O-N 3.17Å; N241-G295 WeakPolarHBondContact OD1-CA 3.21Å
242Y96.3Very high96.1Very high6 Ų622.1 Ų22.12%0.02411%0.113CC..Hα-helixtrans-66.3-47.4175.1-172-110.7000111.7M40 Y47 K202 I206 S238 D239 Y240 E244 A245 I246M40-Y242 HydrophobicContact CE-CD1 3.75Å; M40-Y242 HydrophobicContact CE-CE1 3.83Å; Y47-Y242 WeakPolarHBondContact OH-CE1 3.08Å; Y47-Y242 PolarHBondContact OH-OH 3.31Å; K202-Y242 HydrophobicContact CB-CD2 3.44Å; K202-Y242 VanDerWaalsContact CB-CD2 3.44Å; K202-Y242 HydrophobicContact CB-CE2 3.62Å; K202-Y242 HydrophobicContact CB-CG 4.18Å; K202-Y242 HydrophobicContact CD-CD1 4.12Å; K202-Y242 HydrophobicContact CD-CD2 3.85Å; K202-Y242 HydrophobicContact CD-CE2 4.43Å; K202-Y242 HydrophobicContact CD-CG 3.67Å; K202-Y242 HydrophobicContact CG-CD1 4.17Å; K202-Y242 HydrophobicContact CG-CD2 3.48Å; K202-Y242 VanDerWaalsContact CG-CD2 3.48Å; K202-Y242 HydrophobicContact CG-CE1 4.28Å; K202-Y242 HydrophobicContact CG-CE2 3.61Å; K202-Y242 HydrophobicContact CG-CG 3.78Å; I206-Y242 HydrophobicContact CD1-CD2 3.7Å; I206-Y242 HydrophobicContact CD1-CE2 4.2Å; I206-Y242 HydrophobicContact CG1-CD2 4.1Å; I206-Y242 HydrophobicContact CG1-CE2 4.09Å; S238-Y242 WeakPolarHBondContact OG-CD1 3.45Å; D239-Y242 PolarHBondContact O-N 2.85Å; D239-Y242 PolarHBondContact OD1-N 2.88Å; Y240-Y242 VanDerWaalsContact C-N 3.33Å; Y240-Y242 PolarHBondContact O-N 3.32Å; Y242-E244 VanDerWaalsContact C-N 3.3Å; Y242-E244 PolarHBondContact O-N 3.48Å; Y242-A245 PolarHBondContact O-N 3.42Å; Y242-I246 HydrophobicContact CD1-CG1 4.23Å; Y242-I246 HydrophobicContact CD2-CG1 4.41Å; Y242-I246 HydrophobicContact CE1-CD1 4.4Å; Y242-I246 HydrophobicContact CE1-CG1 3.84Å; Y242-I246 HydrophobicContact CE2-CD1 4.13Å; Y242-I246 HydrophobicContact CE2-CG1 4.03Å; Y242-I246 WeakPolarHBondContact O-CG1 3.46Å; Y242-I246 PolarHBondContact O-N 3.18Å
243T97.3Very high94.7Very high0 Ų024.4 Ų24.40%013%0.129CC..Hα-helixtrans-57.9-43.2176.8-66.20000111.7M40 L234 T236 D239 Y240 A245 I246 M247 W264 V273M40-T243 HydrophobicContact SD-CG2 3.78Å; L234-T243 HydrophobicContact CD2-CG2 3.79Å; T236-T243 HydrophobicContact CG2-CG2 4.4Å; D239-T243 WeakPolarHBondContact O-CB 3.35Å; D239-T243 PolarHBondContact O-N 2.83Å; D239-T243 PolarHBondContact O-OG1 3.25Å; D239-T243 VanDerWaalsContact O-OG1 3.06Å; Y240-T243 PolarHBondContact O-N 3.12Å; T243-A245 PolarHBondContact O-N 3.06Å; T243-I246 PolarHBondContact O-N 2.81Å; T243-M247 HydrophobicContact CG2-CG 3.92Å; T243-M247 WeakPolarHBondContact O-CB 3.11Å; T243-M247 WeakPolarHBondContact O-CG 3.32Å; T243-M247 PolarHBondContact O-N 3.36Å; T243-W264 HydrophobicContact CG2-CH2 3.88Å; T243-W264 HydrophobicContact CG2-CZ2 4.4Å; T243-V273 HydrophobicContact CG2-CG1 4.26Å
244E96.1Very high92.9Very high30 Ų3028.3 Ų28.314%0.1415%0.153CC..Hα-helixtrans-62-45.4178.5-177.5173.1-151.200111.7Y240 Y242 K248Y240-E244 HydrophobicContact CE1-CB 4.37Å; Y240-E244 WeakPolarHBondContact CE1-OE2 3.39Å; Y240-E244 HydrophobicContact CE2-CB 4.38Å; Y240-E244 VanDerWaalsContact O-CB 3.29Å; Y240-E244 WeakPolarHBondContact O-CB 3.29Å; Y240-E244 PolarHBondContact O-N 3.24Å; Y240-E244 VanDerWaalsContact OH-CD 3.31Å; Y240-E244 PolarHBondContact OH-OE1 3.42Å; Y240-E244 PolarHBondContact OH-OE2 2.78Å; Y242-E244 VanDerWaalsContact C-N 3.3Å; Y242-E244 PolarHBondContact O-N 3.48Å; E244-K248 HydrophobicContact CG-CD 3.97Å; E244-K248 HydrophobicContact CG-CG 4.35Å; E244-K248 VanDerWaalsContact O-CB 3.31Å; E244-K248 WeakPolarHBondContact O-CB 3.37Å; E244-K248 WeakPolarHBondContact O-CG 3.37Å; E244-K248 PolarHBondContact O-N 2.87Å; E244-K248 WeakPolarHBondContact OE1-CE 3.45Å; E244-K248 IonicContact OE1-NZ 2.69Å; E244-K248 PolarHBondContact OE1-NZ 3.06Å; E244-K248 IonicContact OE2-NZ 3.51Å
245A96.5Very high90.7Very high24 Ų2432.4 Ų32.420%0.19818%0.179CC..Hα-helixtrans-61.8-47.5179.200000112.2I206 N241 Y242 T243 Y249I206-A245 HydrophobicContact CD1-CB 3.73Å; I206-A245 HydrophobicContact CG1-CB 3.92Å; I206-A245 HydrophobicContact CG2-CB 4.39Å; N241-A245 PolarHBondContact O-N 2.83Å; N241-A245 VanDerWaalsContact O-N 3.17Å; Y242-A245 PolarHBondContact O-N 3.42Å; T243-A245 PolarHBondContact O-N 3.06Å; A245-Y249 PolarHBondContact O-N 2.66Å
246I97.4Very high88.8Confident0 Ų040.9 Ų40.90%022%0.216CC..Hα-helixtrans-65.2-47.7179.5-64.2-67.6000110.9M40 A45 L209 V213 Y242 T243 K248 Y249 L250M40-I246 HydrophobicContact CE-CG1 4.48Å; M40-I246 HydrophobicContact CG-CG2 4.35Å; M40-I246 HydrophobicContact SD-CB 4.14Å; M40-I246 HydrophobicContact SD-CG2 4.07Å; A45-I246 HydrophobicContact CB-CG2 3.5Å; A45-I246 VanDerWaalsContact CB-CG2 3.5Å; L209-I246 HydrophobicContact CD2-CD1 3.55Å; V213-I246 HydrophobicContact CG2-CD1 4.07Å; Y242-I246 HydrophobicContact CD1-CG1 4.23Å; Y242-I246 HydrophobicContact CD2-CG1 4.41Å; Y242-I246 HydrophobicContact CE1-CD1 4.4Å; Y242-I246 HydrophobicContact CE1-CG1 3.84Å; Y242-I246 HydrophobicContact CE2-CD1 4.13Å; Y242-I246 HydrophobicContact CE2-CG1 4.03Å; Y242-I246 WeakPolarHBondContact O-CG1 3.46Å; Y242-I246 PolarHBondContact O-N 3.18Å; T243-I246 PolarHBondContact O-N 2.81Å; I246-K248 PolarHBondContact O-N 3.11Å; I246-Y249 WeakPolarHBondContact O-CB 3.19Å; I246-Y249 PolarHBondContact O-N 2.86Å; I246-L250 HydrophobicContact CG2-CD1 3.93Å; I246-L250 HydrophobicContact CG2-CG 4.42Å; I246-L250 WeakPolarHBondContact O-CG 3.45Å; I246-L250 PolarHBondContact O-N 2.91Å
247M97Very high86.5Confident1 Ų147.3 Ų47.31%0.00526%0.261CS..Hα-helixtrans-69.8-33.5-176.1-65.9-56.9-69.600112.6M40 L44 L234 T243 L250 L251 W264 F268M40-M247 HydrophobicContact CG-SD 4.08Å; M40-M247 HydrophobicContact SD-CG 4.19Å; M40-M247 HydrophobicContact SD-SD 4.3Å; L44-M247 HydrophobicContact CD1-CE 4.16Å; L234-M247 HydrophobicContact CD2-CG 4.44Å; T243-M247 HydrophobicContact CG2-CG 3.92Å; T243-M247 WeakPolarHBondContact O-CB 3.11Å; T243-M247 WeakPolarHBondContact O-CG 3.32Å; T243-M247 PolarHBondContact O-N 3.36Å; M247-L250 PolarHBondContact O-N 2.79Å; M247-L250 HydrophobicContact SD-CD1 4.28Å; M247-L251 HydrophobicContact CE-CD1 3.56Å; M247-L251 HydrophobicContact CE-CG 4.21Å; M247-L251 WeakPolarHBondContact O-CB 3.37Å; M247-L251 PolarHBondContact O-N 3.22Å; M247-W264 HydrophobicContact CB-CB 4.11Å; M247-W264 HydrophobicContact CB-CD2 3.44Å; M247-W264 VanDerWaalsContact CB-CD2 3.44Å; M247-W264 HydrophobicContact CB-CE3 3.53Å; M247-W264 HydrophobicContact CB-CG 3.73Å; M247-W264 HydrophobicContact CB-CH2 4.49Å; M247-W264 HydrophobicContact CB-CZ2 4.45Å; M247-W264 HydrophobicContact CB-CZ3 4.08Å; M247-W264 HydrophobicContact CE-CE3 4.1Å; M247-W264 HydrophobicContact CE-CZ3 4.46Å; M247-W264 HydrophobicContact CG-CD2 4.24Å; M247-W264 HydrophobicContact CG-CE3 3.87Å; M247-W264 HydrophobicContact CG-CH2 4.39Å; M247-W264 HydrophobicContact CG-CZ3 3.96Å; M247-F268 HydrophobicContact CE-CE2 3.46Å; M247-F268 VanDerWaalsContact CE-CE2 3.46Å; M247-F268 HydrophobicContact CE-CZ 3.45Å; M247-F268 VanDerWaalsContact CE-CZ 3.45Å
248K95.4Very high84.8Confident81 Ų8147.8 Ų47.835%0.35228%0.283SS..Hα-helixtrans-60.1-46.9169.3-77.3179.8177.2165.30111.3E244 I246 L250 E252 S253E244-K248 HydrophobicContact CG-CD 3.97Å; E244-K248 HydrophobicContact CG-CG 4.35Å; E244-K248 VanDerWaalsContact O-CB 3.31Å; E244-K248 WeakPolarHBondContact O-CB 3.37Å; E244-K248 WeakPolarHBondContact O-CG 3.37Å; E244-K248 PolarHBondContact O-N 2.87Å; E244-K248 WeakPolarHBondContact OE1-CE 3.45Å; E244-K248 IonicContact OE1-NZ 2.69Å; E244-K248 PolarHBondContact OE1-NZ 3.06Å; E244-K248 IonicContact OE2-NZ 3.51Å; I246-K248 PolarHBondContact O-N 3.11Å; K248-L250 VanDerWaalsContact C-N 3.35Å; K248-L250 PolarHBondContact O-N 3.18Å; K248-E252 HydrophobicContact CG-CG 4.48Å; K248-E252 WeakPolarHBondContact O-CB 3.42Å; K248-E252 PolarHBondContact O-N 2.78Å; K248-S253 PolarHBondContact O-OG 3.26Å
249Y95.5Very high83.2Confident26 Ų2650.2 Ų50.210%0.10230%0.3CS..Hα-helixtrans-59.5-44.4178.2176.9-100.9000112.4L209 E210 V213 K215 A245 I246 S253L209-Y249 HydrophobicContact CB-CD1 4.29Å; L209-Y249 HydrophobicContact CB-CD2 3.84Å; L209-Y249 HydrophobicContact CB-CE1 4.31Å; L209-Y249 HydrophobicContact CB-CE2 3.86Å; L209-Y249 HydrophobicContact CB-CG 4.06Å; L209-Y249 HydrophobicContact CD1-CD2 3.93Å; L209-Y249 HydrophobicContact CD1-CG 3.86Å; L209-Y249 HydrophobicContact CG-CG 4.5Å; E210-Y249 HydrophobicContact CG-CE2 4.07Å; V213-Y249 HydrophobicContact CB-CD1 4.43Å; V213-Y249 HydrophobicContact CB-CE1 4.09Å; V213-Y249 HydrophobicContact CG1-CD1 4.31Å; V213-Y249 HydrophobicContact CG1-CE1 4.22Å; K215-Y249 HydrophobicContact CB-CE1 3.81Å; K215-Y249 HydrophobicContact CD-CE1 4.04Å; K215-Y249 HydrophobicContact CD-CE2 4.14Å; K215-Y249 WeakPolarHBondContact CE-O 3.45Å; K215-Y249 HydrophobicContact CG-CE1 4.12Å; A245-Y249 PolarHBondContact O-N 2.66Å; I246-Y249 WeakPolarHBondContact O-CB 3.19Å; I246-Y249 PolarHBondContact O-N 2.86Å; Y249-S253 WeakPolarHBondContact O-CB 3.46Å; Y249-S253 PolarHBondContact O-OG 3.17Å
250L95.1Very high81.8Confident5 Ų553.8 Ų53.83%0.02633%0.326CS..Hα-helixtrans-72.1-40.9-179.4-65.3176.6000113.5A45 V213 I219 I246 M247 K248A45-L250 HydrophobicContact CB-CD1 3.88Å; V213-L250 HydrophobicContact CG1-CD2 4.08Å; I219-L250 HydrophobicContact CD1-CD2 4.17Å; I246-L250 HydrophobicContact CG2-CD1 3.93Å; I246-L250 HydrophobicContact CG2-CG 4.42Å; I246-L250 WeakPolarHBondContact O-CG 3.45Å; I246-L250 PolarHBondContact O-N 2.91Å; M247-L250 PolarHBondContact O-N 2.79Å; M247-L250 HydrophobicContact SD-CD1 4.28Å; K248-L250 VanDerWaalsContact C-N 3.35Å; K248-L250 PolarHBondContact O-N 3.18Å
251L94.1Very high80.6Confident8 Ų862.5 Ų62.54%0.04236%0.364CS..Hα-helixtrans-110.9-25-165.8-57.4-173.3000115.7I219 P220 L223 M247 W264 F267 F268I219-L251 HydrophobicContact CB-CD2 4.32Å; I219-L251 HydrophobicContact CG2-CD2 3.72Å; P220-L251 HydrophobicContact CB-CD2 4.31Å; P220-L251 HydrophobicContact CG-CD2 3.79Å; L223-L251 HydrophobicContact CD1-CD1 3.87Å; L223-L251 HydrophobicContact CD1-CD2 3.94Å; M247-L251 HydrophobicContact CE-CD1 3.56Å; M247-L251 HydrophobicContact CE-CG 4.21Å; M247-L251 WeakPolarHBondContact O-CB 3.37Å; M247-L251 PolarHBondContact O-N 3.22Å; L251-W264 HydrophobicContact CB-CB 3.95Å; L251-W264 HydrophobicContact CD1-CB 4.06Å; L251-W264 HydrophobicContact CG-CB 4.47Å; L251-F267 HydrophobicContact CB-CD2 4.3Å; L251-F267 HydrophobicContact CB-CE2 4.05Å; L251-F267 HydrophobicContact CD1-CB 4.17Å; L251-F267 HydrophobicContact CD1-CD2 3.84Å; L251-F267 HydrophobicContact CD1-CE2 4.39Å; L251-F267 HydrophobicContact CD1-CG 4.02Å; L251-F268 HydrophobicContact CD1-CE2 3.89Å; L251-F268 HydrophobicContact CD1-CZ 4.41Å
252E89Confident80.1Confident66 Ų6662 Ų6231%0.30836%0.357SS..THydrogen-bonded Turntrans-100.4-7.5-172.9-61.1-172.5-174.900113.9K248 T254 P263 W264K248-E252 HydrophobicContact CG-CG 4.48Å; K248-E252 WeakPolarHBondContact O-CB 3.42Å; K248-E252 PolarHBondContact O-N 2.78Å; E252-T254 PolarHBondContact O-N 3.26Å; E252-P263 VanDerWaalsContact OE1-CA 3.29Å; E252-P263 WeakPolarHBondContact OE1-CA 3.25Å; E252-W264 HydrophobicContact CG-CB 4.07Å; E252-W264 VanDerWaalsContact OE1-CD1 3.26Å; E252-W264 PolarHBondContact OE1-N 3.11Å
253S69.3Low79.8Confident48 Ų4864.7 Ų64.734%0.33638%0.375SS..SBendtrans-88.31.9-165.3-52.40000115.8K215 K248 Y249 P255K215-S253 VanDerWaalsContact CE-CB 3.49Å; K248-S253 PolarHBondContact O-OG 3.26Å; Y249-S253 WeakPolarHBondContact O-CB 3.46Å; Y249-S253 PolarHBondContact O-OG 3.17Å; S253-P255 WeakPolarHBondContact O-CD 3.4Å
254T59.5Low79.7Confident83 Ų8364.7 Ų64.751%0.50938%0.375SS..  trans-122.779.4-177.436.80000112.1E252 K256E252-T254 PolarHBondContact O-N 3.26Å; T254-K256 PolarHBondContact O-N 3.32Å
255P53.9Low79.6Confident86 Ų8666.5 Ų66.556%0.55838%0.381SS*.  trans-71.3111.816327.7-26.3000108.2S253 S257S253-P255 WeakPolarHBondContact O-CD 3.4Å; P255-S257 PolarHBondContact O-N 3.17Å
256K56.4Low79.5Confident177 Ų17766.5 Ų66.577%0.7738%0.381SS*.  trans-58.4129.6148.8-74.7-178.2179.5179.90105.6T254 G258 S259T254-K256 PolarHBondContact O-N 3.32Å; K256-G258 PolarHBondContact O-N 3.16Å; K256-S259 PolarHBondContact O-N 2.66Å; K256-S259 PolarHBondContact O-OG 3.1Å; K256-S259 VanDerWaalsContact O-OG 3.06Å
257S50.9Low79.4Confident135 Ų13567 Ų6794%0.94438%0.383SS*.THydrogen-bonded Turntrans-50114.5-179.3-1680000109.5P255P255-S257 PolarHBondContact O-N 3.17Å
258G58.9Low79.4Confident82 Ų8267.1 Ų67.185%0.84538%0.384SS*.THydrogen-bonded Turntrans102-7.5179.800000118.1K256K256-G258 PolarHBondContact O-N 3.16Å
259S61.7Low79.4Confident59 Ų5965 Ų6541%0.41338%0.376SS..  trans-87.9137.8174.657.30000112.4K256 K261K256-S259 PolarHBondContact O-N 2.66Å; K256-S259 PolarHBondContact O-OG 3.1Å; K256-S259 VanDerWaalsContact O-OG 3.06Å; S259-K261 PolarHBondContact O-N 3.38Å
260P65.9Low79.5Confident121 Ų12163.8 Ų63.879%0.78637%0.372SS*.  trans-59.4138.3176.423.3-31.1000110.9K262P260-K262 PolarHBondContact O-N 2.65Å; P260-K262 VanDerWaalsContact O-N 3.07Å
261K71.1Confident79.6Confident186 Ų18663.8 Ų63.881%0.80937%0.372SS*.  trans-63111.5175.3-74.6-173.1177.8-176.50109S259S259-K261 PolarHBondContact O-N 3.38Å
262K84.3Confident79.8Confident78 Ų7863.5 Ų63.534%0.33937%0.371SS..  trans-88.3121174.7-175.4175.5178.5-1760108.7P260 A266 F267P260-K262 PolarHBondContact O-N 2.65Å; P260-K262 VanDerWaalsContact O-N 3.07Å; K262-A266 HydrophobicContact CD-CB 4.39Å; K262-A266 HydrophobicContact CG-CB 3.88Å; K262-F267 HydrophobicContact CB-CE2 4.39Å; K262-F267 HydrophobicContact CD-CD2 4.35Å; K262-F267 HydrophobicContact CD-CE1 4.33Å; K262-F267 HydrophobicContact CD-CE2 3.87Å; K262-F267 HydrophobicContact CD-CZ 3.87Å; K262-F267 HydrophobicContact CG-CD2 4.5Å; K262-F267 HydrophobicContact CG-CE2 3.97Å; K262-F267 HydrophobicContact CG-CZ 4.39Å
263P91.5Very high80.2Confident62 Ų6260.4 Ų60.440%0.40336%0.356SS..  trans-65147.3176.427-33.2000110.5E252 R265 A266E252-P263 VanDerWaalsContact OE1-CA 3.29Å; E252-P263 WeakPolarHBondContact OE1-CA 3.25Å; P263-R265 PolarHBondContact O-N 2.88Å; P263-R265 VanDerWaalsContact O-N 3.16Å; P263-A266 HydrophobicContact CG-CB 4.08Å; P263-A266 WeakPolarHBondContact O-CB 3.08Å; P263-A266 PolarHBondContact O-N 2.87Å
264W94.4Very high81.5Confident0 Ų060.2 Ų60.20%035%0.351CS..G310 helixtrans-57.5-35.4-175.676.3-97.2000112.1L234 Y240 T243 M247 L251 E252 A266 F267 F268 V271L234-W264 HydrophobicContact CD2-CH2 4.4Å; L234-W264 HydrophobicContact CD2-CZ3 4Å; Y240-W264 HydrophobicContact CE2-CZ2 4.31Å; T243-W264 HydrophobicContact CG2-CH2 3.88Å; T243-W264 HydrophobicContact CG2-CZ2 4.4Å; M247-W264 HydrophobicContact CB-CB 4.11Å; M247-W264 HydrophobicContact CB-CD2 3.44Å; M247-W264 VanDerWaalsContact CB-CD2 3.44Å; M247-W264 HydrophobicContact CB-CE3 3.53Å; M247-W264 HydrophobicContact CB-CG 3.73Å; M247-W264 HydrophobicContact CB-CH2 4.49Å; M247-W264 HydrophobicContact CB-CZ2 4.45Å; M247-W264 HydrophobicContact CB-CZ3 4.08Å; M247-W264 HydrophobicContact CE-CE3 4.1Å; M247-W264 HydrophobicContact CE-CZ3 4.46Å; M247-W264 HydrophobicContact CG-CD2 4.24Å; M247-W264 HydrophobicContact CG-CE3 3.87Å; M247-W264 HydrophobicContact CG-CH2 4.39Å; M247-W264 HydrophobicContact CG-CZ3 3.96Å; L251-W264 HydrophobicContact CB-CB 3.95Å; L251-W264 HydrophobicContact CD1-CB 4.06Å; L251-W264 HydrophobicContact CG-CB 4.47Å; E252-W264 HydrophobicContact CG-CB 4.07Å; E252-W264 VanDerWaalsContact OE1-CD1 3.26Å; E252-W264 PolarHBondContact OE1-N 3.11Å; W264-A266 PolarHBondContact O-N 2.97Å; W264-F267 WeakPolarHBondContact O-CB 3.44Å; W264-F267 WeakPolarHBondContact O-CD2 3.28Å; W264-F267 PolarHBondContact O-N 2.93Å; W264-F267 VanDerWaalsContact O-N 3.14Å; W264-F268 AromaticContact CE3-CD2 3.97Å; W264-F268 HydrophobicContact CE3-CD2 3.97Å; W264-F268 AromaticContact CE3-CE2 3.89Å; W264-F268 HydrophobicContact CE3-CE2 3.89Å; W264-F268 HydrophobicContact CZ3-CD2 4.07Å; W264-F268 HydrophobicContact CZ3-CE2 4.16Å; W264-F268 WeakPolarHBondContact O-CD2 3.29Å; W264-V271 HydrophobicContact CH2-CG1 3.78Å; W264-V271 HydrophobicContact CH2-CG2 4.29Å; W264-V271 HydrophobicContact CZ3-CG1 4.18Å; W264-V271 HydrophobicContact CZ3-CG2 4.06Å
265R94.4Very high83.2Confident68 Ų6856.2 Ų56.226%0.25733%0.327SS..G310 helixtrans-60.3-30.9177.6-70.5177.5-81.8172.6-10.8112.7P263 F267 F268 T292P263-R265 PolarHBondContact O-N 2.88Å; P263-R265 VanDerWaalsContact O-N 3.16Å; R265-F267 PolarHBondContact O-N 2.87Å; R265-F267 VanDerWaalsContact O-N 3.16Å; R265-F268 PolarHBondContact O-N 3.29Å; R265-F268 VanDerWaalsContact O-O 3.08Å; R265-T292 PolarHBondContact NH1-OG1 2.77Å
266A93.6Very high85.1Confident24 Ų2460.1 Ų60.120%0.19833%0.33CS..G310 helixtrans-69.7-11.7-179.400000113.4K227 K262 P263 W264 F268K227-A266 PolarHBondContact NZ-O 3.5Å; K262-A266 HydrophobicContact CD-CB 4.39Å; K262-A266 HydrophobicContact CG-CB 3.88Å; P263-A266 HydrophobicContact CG-CB 4.08Å; P263-A266 WeakPolarHBondContact O-CB 3.08Å; P263-A266 PolarHBondContact O-N 2.87Å; W264-A266 PolarHBondContact O-N 2.97Å; A266-F268 VanDerWaalsContact C-N 3.27Å
267F95Very high86.9Confident10 Ų1052.3 Ų52.34%0.04430%0.296CS..G310 helixtrans-76.2-16171-68.1-93.6000112.7P220 L223 T224 L251 K262 W264 R265P220-F267 HydrophobicContact CB-CE1 3.88Å; P220-F267 HydrophobicContact CB-CZ 3.98Å; L223-F267 HydrophobicContact CB-CB 4.35Å; L223-F267 HydrophobicContact CB-CD1 3.81Å; L223-F267 HydrophobicContact CB-CG 4.5Å; L223-F267 HydrophobicContact CD1-CB 4.17Å; L223-F267 HydrophobicContact CD1-CD1 4.42Å; L223-F267 HydrophobicContact CD1-CG 4.49Å; T224-F267 WeakPolarHBondContact OG1-CE1 3.16Å; L251-F267 HydrophobicContact CB-CD2 4.3Å; L251-F267 HydrophobicContact CB-CE2 4.05Å; L251-F267 HydrophobicContact CD1-CB 4.17Å; L251-F267 HydrophobicContact CD1-CD2 3.84Å; L251-F267 HydrophobicContact CD1-CE2 4.39Å; L251-F267 HydrophobicContact CD1-CG 4.02Å; K262-F267 HydrophobicContact CB-CE2 4.39Å; K262-F267 HydrophobicContact CD-CD2 4.35Å; K262-F267 HydrophobicContact CD-CE1 4.33Å; K262-F267 HydrophobicContact CD-CE2 3.87Å; K262-F267 HydrophobicContact CD-CZ 3.87Å; K262-F267 HydrophobicContact CG-CD2 4.5Å; K262-F267 HydrophobicContact CG-CE2 3.97Å; K262-F267 HydrophobicContact CG-CZ 4.39Å; W264-F267 WeakPolarHBondContact O-CB 3.44Å; W264-F267 WeakPolarHBondContact O-CD2 3.28Å; W264-F267 PolarHBondContact O-N 2.93Å; W264-F267 VanDerWaalsContact O-N 3.14Å; R265-F267 PolarHBondContact O-N 2.87Å; R265-F267 VanDerWaalsContact O-N 3.16Å
268F96.8Very high89Confident4 Ų448.1 Ų48.12%0.01827%0.266CS..  trans-115.5146.3-176.4-57.3-85.4000110.3L44 L223 K227 I232 L234 M247 L251 W264 R265 A266 V271L44-F268 HydrophobicContact CD1-CZ 4.22Å; L223-F268 HydrophobicContact CD1-CE2 4.43Å; L223-F268 HydrophobicContact CD1-CZ 3.88Å; K227-F268 PolarHBondContact NZ-O 3.18Å; I232-F268 HydrophobicContact CB-CD1 4.5Å; I232-F268 HydrophobicContact CG2-CD1 3.65Å; I232-F268 HydrophobicContact CG2-CE1 3.91Å; L234-F268 HydrophobicContact CB-CD1 3.83Å; L234-F268 HydrophobicContact CB-CE1 3.91Å; L234-F268 HydrophobicContact CB-CG 4.35Å; L234-F268 HydrophobicContact CB-CZ 4.49Å; L234-F268 HydrophobicContact CD1-CE1 4.4Å; M247-F268 HydrophobicContact CE-CE2 3.46Å; M247-F268 VanDerWaalsContact CE-CE2 3.46Å; M247-F268 HydrophobicContact CE-CZ 3.45Å; M247-F268 VanDerWaalsContact CE-CZ 3.45Å; L251-F268 HydrophobicContact CD1-CE2 3.89Å; L251-F268 HydrophobicContact CD1-CZ 4.41Å; W264-F268 AromaticContact CE3-CD2 3.97Å; W264-F268 HydrophobicContact CE3-CD2 3.97Å; W264-F268 AromaticContact CE3-CE2 3.89Å; W264-F268 HydrophobicContact CE3-CE2 3.89Å; W264-F268 HydrophobicContact CZ3-CD2 4.07Å; W264-F268 HydrophobicContact CZ3-CE2 4.16Å; W264-F268 WeakPolarHBondContact O-CD2 3.29Å; R265-F268 PolarHBondContact O-N 3.29Å; R265-F268 VanDerWaalsContact O-O 3.08Å; A266-F268 VanDerWaalsContact C-N 3.27Å; F268-V271 HydrophobicContact CB-CG2 3.69Å; F268-V271 HydrophobicContact CD2-CG2 4.4Å; F268-V271 HydrophobicContact CG-CG2 4.15Å
269D96.5Very high90.6Very high36 Ų3647.8 Ų47.819%0.19324%0.244CC..SBendtrans-89.8-27.1171-57.2-56.7000110.9K227 K231 I232 L324K227-D269 WeakPolarHBondContact CE-OD1 3.29Å; K227-D269 IonicContact NZ-OD1 2.68Å; K227-D269 PolarHBondContact NZ-OD1 2.57Å; K231-D269 VanDerWaalsContact CA-OD2 3.26Å; K231-D269 WeakPolarHBondContact CA-OD2 3.43Å; I232-D269 PolarHBondContact N-OD2 2.66Å; I232-D269 PolarHBondContact O-N 3.24Å; D269-L324 HydrophobicContact CB-CD2 4.17Å
270L96.6Very high92.2Very high2 Ų245 Ų451%0.0123%0.225CC..EExtended strand (participates in β ladder)trans-140138.3172.6-17777.2000110.8I232 F233 L234 V272 L306 Y312 V320 L323 L324I232-L270 PolarHBondContact O-N 2.96Å; F233-L270 CarbonylContact C-O 3.43Å; F233-L270 WeakPolarHBondContact CA-O 3.48Å; F233-L270 HydrophobicContact CB-CB 3.85Å; F233-L270 HydrophobicContact CB-CD2 4.42Å; F233-L270 WeakPolarHBondContact CB-O 3.48Å; L234-L270 PolarHBondContact N-O 3.44Å; L270-V272 HydrophobicContact CD1-CG2 4.48Å; L270-V272 HydrophobicContact CD2-CG2 3.8Å; L270-V272 HydrophobicContact CG-CG2 3.89Å; L270-L306 HydrophobicContact CD1-CD1 3.47Å; L270-L306 VanDerWaalsContact CD1-CD1 3.47Å; L270-Y312 HydrophobicContact CD1-CD2 3.41Å; L270-Y312 VanDerWaalsContact CD1-CD2 3.41Å; L270-Y312 HydrophobicContact CD1-CE2 3.35Å; L270-Y312 HydrophobicContact CG-CD2 4.45Å; L270-V320 HydrophobicContact CD2-CB 4.06Å; L270-V320 HydrophobicContact CD2-CG1 3.74Å; L270-V320 HydrophobicContact CD2-CG2 3.71Å; L270-L323 HydrophobicContact CD1-CD1 4.01Å; L270-L324 HydrophobicContact CB-CD1 4.11Å; L270-L324 HydrophobicContact CB-CD2 3.92Å; L270-L324 HydrophobicContact CB-CG 4.19Å; L270-L324 HydrophobicContact CD2-CD1 3.97Å; L270-L324 HydrophobicContact CD2-CG 4.14Å
271V97.8Very high93.5Very high5 Ų539.3 Ų39.33%0.0319%0.188CC..EExtended strand (participates in β ladder)trans-125.6123.2172.7179.70000108.7L234 W264 F268 V273 V311 Y312L234-V271 HydrophobicContact CB-CG1 4.4Å; L234-V271 HydrophobicContact CD2-CG1 4.23Å; W264-V271 HydrophobicContact CH2-CG1 3.78Å; W264-V271 HydrophobicContact CH2-CG2 4.29Å; W264-V271 HydrophobicContact CZ3-CG1 4.18Å; W264-V271 HydrophobicContact CZ3-CG2 4.06Å; F268-V271 HydrophobicContact CB-CG2 3.69Å; F268-V271 HydrophobicContact CD2-CG2 4.4Å; F268-V271 HydrophobicContact CG-CG2 4.15Å; V271-V273 HydrophobicContact CG1-CG1 4.44Å; V271-V311 HydrophobicContact CB-CG1 4.32Å; V271-V311 HydrophobicContact CB-CG2 4.26Å; V271-V311 HydrophobicContact CG1-CG1 3.85Å; V271-V311 HydrophobicContact CG1-CG2 4.27Å; V271-Y312 PolarHBondContact O-N 3.34Å
272V97.7Very high94.4Very high2 Ų231.2 Ų31.21%0.01216%0.156CC..EExtended strand (participates in β ladder)trans-125.9119.5176.4-164.60000109.6L234 A235 T236 L270 T275 F280 Y312 G314 V320L234-V272 PolarHBondContact O-N 3.01Å; A235-V272 WeakPolarHBondContact CA-O 3.45Å; T236-V272 PolarHBondContact N-O 3.47Å; L270-V272 HydrophobicContact CD1-CG2 4.48Å; L270-V272 HydrophobicContact CD2-CG2 3.8Å; L270-V272 HydrophobicContact CG-CG2 3.89Å; V272-T275 HydrophobicContact CB-CG2 4.09Å; V272-T275 HydrophobicContact CG1-CG2 3.75Å; V272-F280 HydrophobicContact CG1-CE2 4.48Å; V272-Y312 CarbonylContact C-O 3.56Å; V272-Y312 WeakPolarHBondContact CA-O 3.35Å; V272-G314 VanDerWaalsContact CG1-O 3.24Å; V272-G314 WeakPolarHBondContact CG1-O 3.5Å; V272-V320 HydrophobicContact CG2-CG2 3.95Å
273V97.8Very high94.7Very high0 Ų034.7 Ų34.70%018%0.178CC..EExtended strand (participates in β ladder)trans-103.7172.5175.4-61.90000110.4T236 S238 T243 V271 T275 V290 V311 Y312 S313 G314T236-V273 HydrophobicContact CG2-CB 4.5Å; T236-V273 HydrophobicContact CG2-CG1 4.12Å; T236-V273 CarbonylContact O-C 3.24Å; S238-V273 WeakPolarHBondContact O-CB 3.25Å; T243-V273 HydrophobicContact CG2-CG1 4.26Å; V271-V273 HydrophobicContact CG1-CG1 4.44Å; V273-T275 PolarHBondContact O-N 3.06Å; V273-V290 HydrophobicContact CG2-CG2 3.92Å; V273-V311 HydrophobicContact CG1-CG1 4.27Å; V273-V311 HydrophobicContact CG2-CG1 4.29Å; V273-Y312 VanDerWaalsContact CG2-O 3.28Å; V273-Y312 WeakPolarHBondContact CG2-O 3.34Å; V273-Y312 PolarHBondContact N-O 3.02Å; V273-S313 CarbonylContact O-C 3.58Å; V273-S313 VanDerWaalsContact O-CA 3.29Å; V273-S313 WeakPolarHBondContact O-CA 3.49Å; V273-G314 PolarHBondContact O-N 3.02Å
274D96Very high94.8Very high44 Ų4432.2 Ų32.224%0.23516%0.164CC..  trans50.934.7178.3-48.9-61.6000114.3T236 S238 D239 R276 S313T236-D274 PolarHBondContact O-N 3.37Å; S238-D274 PolarHBondContact O-N 3.42Å; D239-D274 WeakPolarHBondContact CA-OD1 3.48Å; D274-R276 PolarHBondContact O-N 3.36Å; D274-S313 WeakPolarHBondContact CB-OG 3.45Å; D274-S313 PolarHBondContact OD2-OG 2.89Å
275T95.7Very high94.8Very high0 Ų034.1 Ų34.10%018%0.175CC..  trans-64.6-23.6-171.950.80000113.7A235 T236 N237 V272 V273 K277 F280A235-T275 HydrophobicContact CB-CG2 4.13Å; T236-T275 WeakPolarHBondContact O-CG2 3.45Å; T236-T275 PolarHBondContact O-N 3.18Å; T236-T275 PolarHBondContact O-OG1 3.06Å; N237-T275 PolarHBondContact N-OG1 3.02Å; N237-T275 PolarHBondContact OD1-OG1 3.45Å; V272-T275 HydrophobicContact CB-CG2 4.09Å; V272-T275 HydrophobicContact CG1-CG2 3.75Å; V273-T275 PolarHBondContact O-N 3.06Å; T275-K277 VanDerWaalsContact C-N 3.3Å; T275-K277 PolarHBondContact O-N 3.15Å; T275-F280 HydrophobicContact CG2-CD2 3.84Å; T275-F280 HydrophobicContact CG2-CE2 3.8Å; T275-F280 HydrophobicContact CG2-CG 4.35Å; T275-F280 HydrophobicContact CG2-CZ 4.29Å; T275-F280 WeakPolarHBondContact O-CB 3.39Å
276R93.7Very high94.7Very high168 Ų16834.3 Ų34.363%0.63418%0.184SC*.  trans55.540.3-178.3-59.6-178.8-178.6-166.2-4.1113.1N237 D274 L279N237-R276 WeakPolarHBondContact OD1-CA 3.43Å; N237-R276 PolarHBondContact OD1-N 2.88Å; D274-R276 PolarHBondContact O-N 3.36Å; R276-L279 VanDerWaalsContact O-CB 3.26Å; R276-L279 WeakPolarHBondContact O-CB 3.35Å; R276-L279 PolarHBondContact O-N 3.3Å
277K95.2Very high94.8Very high12 Ų1233.8 Ų33.85%0.05218%0.178CC..THydrogen-bonded Turntrans-52.5134.2171.1-63.8172.4-63.7168.70109.3D39 A235 N237 T275 F280 F281 Y333 D341D39-K277 IonicContact OD1-NZ 3.93Å; D39-K277 PolarHBondContact OD1-NZ 3.44Å; D39-K277 VanDerWaalsContact OD1-NZ 3.1Å; D39-K277 IonicContact OD2-NZ 2.69Å; D39-K277 PolarHBondContact OD2-NZ 3.35Å; A235-K277 PolarHBondContact O-NZ 2.86Å; N237-K277 PolarHBondContact ND2-O 2.94Å; N237-K277 WeakPolarHBondContact OD1-CB 3.26Å; N237-K277 WeakPolarHBondContact OD1-CE 3.41Å; N237-K277 PolarHBondContact OD1-N 3.22Å; T275-K277 VanDerWaalsContact C-N 3.3Å; T275-K277 PolarHBondContact O-N 3.15Å; K277-F280 HydrophobicContact CB-CB 4.49Å; K277-F280 HydrophobicContact CG-CB 3.7Å; K277-F280 HydrophobicContact CG-CD1 4.32Å; K277-F280 HydrophobicContact CG-CG 4.24Å; K277-F281 HydrophobicContact CB-CE2 4.34Å; K277-F281 HydrophobicContact CD-CE2 3.87Å; K277-F281 HydrophobicContact CD-CZ 4.21Å; K277-F281 HydrophobicContact CG-CD2 4.43Å; K277-F281 HydrophobicContact CG-CE2 3.83Å; K277-F281 HydrophobicContact CG-CZ 4.48Å; K277-Y333 PolarHBondContact NZ-OH 3.44Å; K277-Y333 VanDerWaalsContact NZ-OH 3.08Å; K277-D341 VanDerWaalsContact CD-OD1 3.29Å; K277-D341 WeakPolarHBondContact CD-OD1 3.35Å; K277-D341 WeakPolarHBondContact CE-OD1 3.47Å; K277-D341 IonicContact NZ-OD1 3.25Å; K277-D341 PolarHBondContact NZ-OD1 3.28Å
278P93.4Very high94.7Very high47 Ų4737.3 Ų37.331%0.30519%0.191SC..THydrogen-bonded Turncis-88.2-3.813.634.6-37.6000116.3F280 F281 F339 K344P278-F280 PolarHBondContact O-N 3.44Å; P278-F281 PolarHBondContact O-N 3.11Å; P278-F281 VanDerWaalsContact O-N 3.14Å; P278-F339 HydrophobicContact CB-CE1 4.43Å; P278-F339 HydrophobicContact CG-CE1 4.07Å; P278-K344 HydrophobicContact CB-CB 4.3Å; P278-K344 HydrophobicContact CB-CD 4.19Å; P278-K344 HydrophobicContact CB-CG 3.71Å
279L94.3Very high94.6Very high75 Ų7538.4 Ų38.439%0.39320%0.196SC..G310 helixtrans-59.7-31.2-178.4-177.963.4000111.6R276 F281 A282 G284 T285R276-L279 VanDerWaalsContact O-CB 3.26Å; R276-L279 WeakPolarHBondContact O-CB 3.35Å; R276-L279 PolarHBondContact O-N 3.3Å; L279-F281 VanDerWaalsContact C-N 3.27Å; L279-F281 PolarHBondContact O-N 3.49Å; L279-A282 HydrophobicContact CD1-CB 4.4Å; L279-A282 CarbonylContact O-C 3.58Å; L279-A282 WeakPolarHBondContact O-CA 3.36Å; L279-A282 VanDerWaalsContact O-CB 3.3Å; L279-A282 WeakPolarHBondContact O-CB 3.44Å; L279-A282 PolarHBondContact O-N 3.46Å; L279-G284 VanDerWaalsContact O-CA 3.29Å; L279-G284 WeakPolarHBondContact O-CA 3.49Å; L279-G284 PolarHBondContact O-N 3Å; L279-T285 HydrophobicContact CD2-CG2 3.95Å
280F95.2Very high94.6Very high1 Ų137 Ų370%0.00419%0.188CC..G310 helixtrans-49.9-40.6173.2-171.7-109.2000114.8A235 V272 T275 K277 P278 A282 S316 S317 V320A235-F280 HydrophobicContact CB-CE1 4.39Å; A235-F280 HydrophobicContact CB-CZ 4.47Å; V272-F280 HydrophobicContact CG1-CE2 4.48Å; T275-F280 HydrophobicContact CG2-CD2 3.84Å; T275-F280 HydrophobicContact CG2-CE2 3.8Å; T275-F280 HydrophobicContact CG2-CG 4.35Å; T275-F280 HydrophobicContact CG2-CZ 4.29Å; T275-F280 WeakPolarHBondContact O-CB 3.39Å; K277-F280 HydrophobicContact CB-CB 4.49Å; K277-F280 HydrophobicContact CG-CB 3.7Å; K277-F280 HydrophobicContact CG-CD1 4.32Å; K277-F280 HydrophobicContact CG-CG 4.24Å; P278-F280 PolarHBondContact O-N 3.44Å; F280-A282 PolarHBondContact O-N 2.67Å; F280-S316 CarbonylContact O-C 3.57Å; F280-S316 WeakPolarHBondContact O-CA 3.15Å; F280-S317 PolarHBondContact O-N 3.04Å; F280-V320 HydrophobicContact CE2-CG2 4.39Å; F280-V320 HydrophobicContact CZ-CG2 3.63Å
281F92.8Very high94.4Very high1 Ų138.7 Ų38.70%0.00420%0.198CC..G310 helixtrans-84.85.6179.6-60.1-68.5000113K277 P278 L279 Y333 G340 K344 R348 Q349 W351K277-F281 HydrophobicContact CB-CE2 4.34Å; K277-F281 HydrophobicContact CD-CE2 3.87Å; K277-F281 HydrophobicContact CD-CZ 4.21Å; K277-F281 HydrophobicContact CG-CD2 4.43Å; K277-F281 HydrophobicContact CG-CE2 3.83Å; K277-F281 HydrophobicContact CG-CZ 4.48Å; P278-F281 PolarHBondContact O-N 3.11Å; P278-F281 VanDerWaalsContact O-N 3.14Å; L279-F281 VanDerWaalsContact C-N 3.27Å; L279-F281 PolarHBondContact O-N 3.49Å; F281-Y333 HydrophobicContact CE2-CE1 4.48Å; F281-Y333 HydrophobicContact CZ-CD1 4.07Å; F281-Y333 AromaticContact CZ-CE1 3.69Å; F281-Y333 HydrophobicContact CZ-CE1 3.69Å; F281-G340 VanDerWaalsContact CD2-O 3.25Å; F281-G340 WeakPolarHBondContact CD2-O 3.27Å; F281-G340 WeakPolarHBondContact CE2-O 3.36Å; F281-K344 HydrophobicContact CB-CB 4.13Å; F281-K344 HydrophobicContact CD2-CB 3.96Å; F281-K344 HydrophobicContact CG-CB 4.31Å; F281-R348 WeakPolarHBondContact O-CB 3.4Å; F281-R348 WeakPolarHBondContact O-CD 3.47Å; F281-Q349 HydrophobicContact CD1-CG 4.45Å; F281-W351 AromaticContact CE1-CE3 3.91Å; F281-W351 HydrophobicContact CE1-CE3 3.91Å; F281-W351 HydrophobicContact CE1-CH2 4.15Å; F281-W351 AromaticContact CE1-CZ3 3.62Å; F281-W351 HydrophobicContact CE1-CZ3 3.62Å; F281-W351 HydrophobicContact CZ-CZ3 4.42Å
282A90.7Very high94.2Very high17 Ų1740.1 Ų40.114%0.1421%0.206CC..THydrogen-bonded Turntrans-118.6-131.6179.800000108.4L279 F280 G284L279-A282 HydrophobicContact CD1-CB 4.4Å; L279-A282 CarbonylContact O-C 3.58Å; L279-A282 WeakPolarHBondContact O-CA 3.36Å; L279-A282 VanDerWaalsContact O-CB 3.3Å; L279-A282 WeakPolarHBondContact O-CB 3.44Å; L279-A282 PolarHBondContact O-N 3.46Å; F280-A282 PolarHBondContact O-N 2.67Å; A282-G284 PolarHBondContact O-N 3.14Å
283D89.8Confident93.8Very high150 Ų15047.2 Ų47.280%0.80224%0.244SC*.THydrogen-bonded Turntrans-69.1-14.7179.5-49.9-44.9000112.7
284G93.1Very high93.5Very high10 Ų1050.9 Ų50.910%0.10327%0.267CS..  trans62.1-154.1-179.500000113.1L279 A282 G315L279-G284 VanDerWaalsContact O-CA 3.29Å; L279-G284 WeakPolarHBondContact O-CA 3.49Å; L279-G284 PolarHBondContact O-N 3Å; A282-G284 PolarHBondContact O-N 3.14Å; G284-G315 CarbonylContact C-O 3.56Å; G284-G315 VanDerWaalsContact CA-O 3.25Å; G284-G315 WeakPolarHBondContact CA-O 3.4Å
285T94.4Very high93.3Very high40 Ų4049.5 Ų49.525%0.24526%0.263CS..  trans-135.1174.1173.758.90000110.1L279 L287 G314 G315L279-T285 HydrophobicContact CD2-CG2 3.95Å; T285-L287 PolarHBondContact O-N 3.46Å; T285-G314 WeakPolarHBondContact OG1-CA 3.3Å; T285-G315 PolarHBondContact N-O 3.21Å; T285-G315 CarbonylContact O-C 3.58Å; T285-G315 WeakPolarHBondContact O-CA 3.41Å; T285-G315 PolarHBondContact O-N 3.3Å; T285-G315 PolarHBondContact OG1-N 2.8Å
286V93.6Very high93.1Very high73 Ų7356.8 Ų56.844%0.44230%0.295SS..  trans-60128.5175.1-179.70000110.1R288 T301V286-R288 PolarHBondContact O-N 2.82Å; V286-T301 HydrophobicContact CG1-CG2 3.74Å; V286-T301 WeakPolarHBondContact CG1-OG1 3.41Å
287L94.4Very high93.1Very high13 Ų1352.7 Ų52.77%0.06829%0.285CS..  trans-71.2127.1173.5-170.775.4000110.6T285 Y302 Y312 I319 L323T285-L287 PolarHBondContact O-N 3.46Å; L287-Y302 HydrophobicContact CD2-CD1 3.87Å; L287-Y302 HydrophobicContact CD2-CG 4.42Å; L287-Y302 PolarHBondContact O-N 3.12Å; L287-Y312 HydrophobicContact CD1-CD1 4.31Å; L287-Y312 HydrophobicContact CD1-CG 4.32Å; L287-Y312 HydrophobicContact CD2-CD1 4.12Å; L287-Y312 HydrophobicContact CG-CD1 4.25Å; L287-I319 HydrophobicContact CB-CD1 4.15Å; L287-I319 HydrophobicContact CD1-CG2 4.13Å; L287-I319 HydrophobicContact CD2-CG2 3.76Å; L287-I319 HydrophobicContact CG-CG2 4.41Å; L287-L323 HydrophobicContact CD2-CD1 4.47Å
288R94.1Very high92.8Very high84 Ų8458.2 Ų58.232%0.31731%0.305SS..EExtended strand (participates in β ladder)trans-121.7157.5177.8-63.9-65.6-126.9-90.2-4110.5V286 L297 G300 Y312 S313V286-R288 PolarHBondContact O-N 2.82Å; R288-L297 HydrophobicContact CB-CD1 4.39Å; R288-L297 HydrophobicContact CB-CD2 4.46Å; R288-L297 HydrophobicContact CG-CD1 4.4Å; R288-G300 WeakPolarHBondContact CD-O 3.43Å; R288-G300 PolarHBondContact NE-O 2.74Å; R288-Y312 CarbonylContact O-C 3.52Å; R288-Y312 VanDerWaalsContact O-CA 3.25Å; R288-Y312 WeakPolarHBondContact O-CA 3.44Å; R288-S313 PolarHBondContact N-O 3.14Å; R288-S313 PolarHBondContact O-N 2.92Å
289Q94.5Very high92.5Very high27 Ų2764.4 Ų64.413%0.12633%0.334CS..EExtended strand (participates in β ladder)trans-99.9135.5170.5-170.3179.334.900109.6R298 Y302 T310Q289-R298 HydrophobicContact CB-CB 4.44Å; Q289-R298 WeakPolarHBondContact O-CB 3.31Å; Q289-R298 PolarHBondContact O-N 2.99Å; Q289-R298 VanDerWaalsContact OE1-CD 3.23Å; Q289-Y302 HydrophobicContact CB-CD2 4.04Å; Q289-T310 HydrophobicContact CG-CG2 3.69Å
290V95.3Very high91.9Very high5 Ų562.7 Ų62.73%0.0333%0.334CS..BIsolated β-bridgetrans-87.3132.1173.7-174.90000109.2Y240 V273 T292 L297 V311Y240-V290 HydrophobicContact CD1-CG1 3.85Å; Y240-V290 HydrophobicContact CD2-CG1 4.17Å; Y240-V290 HydrophobicContact CE1-CG1 4.47Å; Y240-V290 HydrophobicContact CG-CG1 3.66Å; V273-V290 HydrophobicContact CG2-CG2 3.92Å; V290-T292 PolarHBondContact O-N 3.43Å; V290-L297 HydrophobicContact CG2-CD2 3.84Å; V290-V311 HydrophobicContact CB-CB 4.1Å; V290-V311 HydrophobicContact CB-CG1 4.13Å; V290-V311 HydrophobicContact CG2-CB 4.34Å; V290-V311 HydrophobicContact CG2-CG1 3.88Å; V290-V311 PolarHBondContact N-O 2.68Å
291D93.5Very high91.3Very high38 Ų3866.6 Ų66.620%0.20336%0.358CS..  trans-77.7106.7162.9175.49.5000108.9D293 T294 G295 K296 R298D291-D293 PolarHBondContact O-N 3.19Å; D291-D293 PolarHBondContact OD1-N 3.05Å; D291-T294 PolarHBondContact O-N 2.78Å; D291-T294 VanDerWaalsContact OD2-CG2 3.29Å; D291-T294 WeakPolarHBondContact OD2-CG2 3.38Å; D291-T294 PolarHBondContact OD2-OG1 2.92Å; D291-G295 VanDerWaalsContact O-CA 3.26Å; D291-G295 WeakPolarHBondContact O-CA 3.36Å; D291-G295 PolarHBondContact O-N 2.78Å; D291-K296 WeakPolarHBondContact CB-O 3.39Å; D291-K296 PolarHBondContact N-O 3.24Å; D291-R298 HydrophobicContact CB-CG 4.21Å
292T92.1Very high90.8Very high35 Ų3568.1 Ų68.122%0.21536%0.364CS..THydrogen-bonded Turntrans-72.1-13.9-172.457.60000113.9Y240 R265 V290 V311Y240-T292 HydrophobicContact CE2-CG2 4.14Å; Y240-T292 WeakPolarHBondContact OH-CB 3.48Å; R265-T292 PolarHBondContact NH1-OG1 2.77Å; V290-T292 PolarHBondContact O-N 3.43Å; T292-V311 HydrophobicContact CG2-CB 4.24Å; T292-V311 HydrophobicContact CG2-CG2 3.91Å
293D91Very high90.3Very high152 Ų15273.7 Ų73.781%0.81340%0.397SS*.THydrogen-bonded Turntrans-83.5-33.9177.3-62.7-33.8000111.4D291D291-D293 PolarHBondContact O-N 3.19Å; D291-D293 PolarHBondContact OD1-N 3.05Å
294T91.3Very high89.9Confident76 Ų7668.2 Ų68.247%0.46638%0.376SS..THydrogen-bonded Turntrans-105.9-15.6-178.565.80000114D291 K296D291-T294 PolarHBondContact O-N 2.78Å; D291-T294 VanDerWaalsContact OD2-CG2 3.29Å; D291-T294 WeakPolarHBondContact OD2-CG2 3.38Å; D291-T294 PolarHBondContact OD2-OG1 2.92Å; T294-K296 PolarHBondContact O-N 3.27Å; T294-K296 PolarHBondContact OG1-N 2.8Å
295G90.4Very high89.4Confident15 Ų1574.6 Ų74.616%0.15541%0.408CS..  trans70.17.7-172.500000114.7N241 D291N241-G295 WeakPolarHBondContact OD1-CA 3.21Å; D291-G295 VanDerWaalsContact O-CA 3.26Å; D291-G295 WeakPolarHBondContact O-CA 3.36Å; D291-G295 PolarHBondContact O-N 2.78Å
296K92.4Very high88.9Confident153 Ų15375.6 Ų75.667%0.66541%0.411SS*.PPolyproline II helixtrans-93.5156.5-177.9-65-178.2-178.9177.70111.6D291 T294D291-K296 WeakPolarHBondContact CB-O 3.39Å; D291-K296 PolarHBondContact N-O 3.24Å; T294-K296 PolarHBondContact O-N 3.27Å; T294-K296 PolarHBondContact OG1-N 2.8Å
297L92.9Very high88.3Confident82 Ų8277.3 Ų77.343%0.42941%0.414SS..BIsolated β-bridgetrans-76.3132.3173.8-55.9-175000110.6R288 V290 S313R288-L297 HydrophobicContact CB-CD1 4.39Å; R288-L297 HydrophobicContact CB-CD2 4.46Å; R288-L297 HydrophobicContact CG-CD1 4.4Å; V290-L297 HydrophobicContact CG2-CD2 3.84Å; L297-S313 VanDerWaalsContact CD2-CB 3.4Å
298R90.4Very high87.5Confident129 Ų12983.4 Ų83.449%0.48744%0.442SS..PPolyproline II helixtrans-66.1146.3168.1-66.6-178.3174.9-168.8-4.9109.9Q289 D291Q289-R298 HydrophobicContact CB-CB 4.44Å; Q289-R298 WeakPolarHBondContact O-CB 3.31Å; Q289-R298 PolarHBondContact O-N 2.99Å; Q289-R298 VanDerWaalsContact OE1-CD 3.23Å; D291-R298 HydrophobicContact CB-CG 4.21Å
299I85.9Confident86.7Confident177 Ų17781.2 Ų81.291%0.90845%0.445SS*.SBendtrans-72.5135.1-179.5-59.9177000109.4
300G82.3Confident86.4Confident38 Ų3881 Ų8139%0.39245%0.446SS..SBendtrans101.3162.8176.900000113.9R288R288-G300 WeakPolarHBondContact CD-O 3.43Å; R288-G300 PolarHBondContact NE-O 2.74Å
301T82.7Confident86.4Confident84 Ų8480.8 Ų80.852%0.51545%0.445SS..  trans-75.9135172.2-56.30000109.3V286 T303V286-T301 HydrophobicContact CG1-CG2 3.74Å; V286-T301 WeakPolarHBondContact CG1-OG1 3.41Å; T301-T303 HydrophobicContact CG2-CG2 4.45Å; T301-T303 PolarHBondContact O-N 2.84Å
302Y81.8Confident86.6Confident33 Ų3379 Ų7913%0.12944%0.435CS..  trans-74.3125.1173.2-174.4-95000110.3L287 Q289 G304 D305 Y312L287-Y302 HydrophobicContact CD2-CD1 3.87Å; L287-Y302 HydrophobicContact CD2-CG 4.42Å; L287-Y302 PolarHBondContact O-N 3.12Å; Q289-Y302 HydrophobicContact CB-CD2 4.04Å; Y302-G304 VanDerWaalsContact CE1-C 3.49Å; Y302-G304 WeakPolarHBondContact CE1-O 3.5Å; Y302-D305 PolarHBondContact OH-O 2.88Å; Y302-Y312 HydrophobicContact CD1-CD1 4.21Å; Y302-Y312 AromaticContact CD1-CE1 3.59Å; Y302-Y312 HydrophobicContact CD1-CE1 3.59Å; Y302-Y312 HydrophobicContact CD2-CE1 4.26Å; Y302-Y312 AromaticContact CE1-CE1 3.47Å; Y302-Y312 HydrophobicContact CE1-CE1 3.47Å; Y302-Y312 VanDerWaalsContact CE1-CE1 3.47Å; Y302-Y312 HydrophobicContact CE2-CE1 4.18Å; Y302-Y312 HydrophobicContact CG-CD1 4.37Å; Y302-Y312 AromaticContact CG-CE1 3.96Å; Y302-Y312 HydrophobicContact CG-CE1 3.96Å; Y302-Y312 AromaticContact CZ-CE1 3.78Å
303T80.3Confident86.8Confident134 Ų13477.6 Ų77.682%0.82243%0.427SS*.  trans-126.516.7-178.963.30000112.7T301T301-T303 HydrophobicContact CG2-CG2 4.45Å; T301-T303 PolarHBondContact O-N 2.84Å
304G81.1Confident87Confident35 Ų3570.5 Ų70.536%0.36139%0.39SS..SBendtrans-93175.2-178.900000113.3Y302Y302-G304 VanDerWaalsContact CE1-C 3.49Å; Y302-G304 WeakPolarHBondContact CE1-O 3.5Å
305D83.2Confident87.2Confident144 Ų14466.9 Ų66.977%0.7737%0.368SS*.  trans-76.3160.4172.3-59.8-41.4000112.1Y302 Q307Y302-D305 PolarHBondContact OH-O 2.88Å; D305-Q307 PolarHBondContact O-N 3.07Å
306L83.1Confident87.5Confident61 Ų6166.7 Ų66.732%0.31936%0.364SS..  trans-55.1113.1177.8179.959000112.3L270 Y312 L323 L324L270-L306 HydrophobicContact CD1-CD1 3.47Å; L270-L306 VanDerWaalsContact CD1-CD1 3.47Å; L306-Y312 HydrophobicContact CD1-CE2 3.92Å; L306-L323 HydrophobicContact CB-CB 4.47Å; L306-L323 HydrophobicContact CB-CD2 4.14Å; L306-L323 WeakPolarHBondContact CD2-O 3.46Å; L306-L324 HydrophobicContact CD2-CD2 4.02Å
307Q81.3Confident87.6Confident108 Ų10859.4 Ų59.451%0.50533%0.333SS..  trans-99.6123.5173.7-70.8179.90.400111.8D305 G309 T310 Y312D305-Q307 PolarHBondContact O-N 3.07Å; Q307-G309 PolarHBondContact O-N 2.85Å; Q307-T310 VanDerWaalsContact CB-OG1 3.31Å; Q307-T310 WeakPolarHBondContact CB-OG1 3.32Å; Q307-T310 VanDerWaalsContact O-CB 3.22Å; Q307-T310 WeakPolarHBondContact O-CB 3.08Å; Q307-T310 PolarHBondContact O-N 2.78Å; Q307-T310 VanDerWaalsContact O-N 3.12Å; Q307-T310 PolarHBondContact O-OG1 3.25Å; Q307-Y312 PolarHBondContact N-OH 3.19Å
308H78.3Confident87.6Confident141 Ų14159 Ų5965%0.65333%0.33SS*.THydrogen-bonded Turntrans-58.4134179-167.970.1000111.8T310H308-T310 PolarHBondContact O-N 3.02Å
309G77.8Confident87.6Confident38 Ų3855.1 Ų55.139%0.39232%0.319SS..THydrogen-bonded Turntrans79.5-3.5-17900000115.3Q307Q307-G309 PolarHBondContact O-N 2.85Å
310T88.1Confident87.9Confident22 Ų2246.8 Ų46.814%0.13528%0.276CS..  trans-74.2144172.3-63.70000110.9Q289 Q307 H308 Y312Q289-T310 HydrophobicContact CG-CG2 3.69Å; Q307-T310 VanDerWaalsContact CB-OG1 3.31Å; Q307-T310 WeakPolarHBondContact CB-OG1 3.32Å; Q307-T310 VanDerWaalsContact O-CB 3.22Å; Q307-T310 WeakPolarHBondContact O-CB 3.08Å; Q307-T310 PolarHBondContact O-N 2.78Å; Q307-T310 VanDerWaalsContact O-N 3.12Å; Q307-T310 PolarHBondContact O-OG1 3.25Å; H308-T310 PolarHBondContact O-N 3.02Å; T310-Y312 HydrophobicContact CG2-CD1 4.32Å; T310-Y312 HydrophobicContact CG2-CD2 4.48Å; T310-Y312 HydrophobicContact CG2-CE1 3.78Å; T310-Y312 HydrophobicContact CG2-CE2 3.97Å
311V95.1Very high88.4Confident1 Ų145.7 Ų45.71%0.00626%0.263CS..EExtended strand (participates in β ladder)trans-111.2133.2172.7-178.40000109.2Y240 V271 V273 V290 T292Y240-V311 HydrophobicContact CD2-CB 4.37Å; Y240-V311 HydrophobicContact CD2-CG1 3.8Å; Y240-V311 HydrophobicContact CD2-CG2 4.36Å; Y240-V311 HydrophobicContact CE2-CB 4.32Å; Y240-V311 HydrophobicContact CE2-CG1 4.19Å; Y240-V311 HydrophobicContact CE2-CG2 3.89Å; V271-V311 HydrophobicContact CB-CG1 4.32Å; V271-V311 HydrophobicContact CB-CG2 4.26Å; V271-V311 HydrophobicContact CG1-CG1 3.85Å; V271-V311 HydrophobicContact CG1-CG2 4.27Å; V273-V311 HydrophobicContact CG1-CG1 4.27Å; V273-V311 HydrophobicContact CG2-CG1 4.29Å; V290-V311 HydrophobicContact CB-CB 4.1Å; V290-V311 HydrophobicContact CB-CG1 4.13Å; V290-V311 HydrophobicContact CG2-CB 4.34Å; V290-V311 HydrophobicContact CG2-CG1 3.88Å; V290-V311 PolarHBondContact N-O 2.68Å; T292-V311 HydrophobicContact CG2-CB 4.24Å; T292-V311 HydrophobicContact CG2-CG2 3.91Å
312Y96.5Very high88.8Confident0 Ų047.8 Ų47.80%027%0.271CS..EExtended strand (participates in β ladder)trans-107.8158179.1-57.2-81.6000110.9L270 V271 V272 V273 L287 R288 Y302 L306 Q307 T310L270-Y312 HydrophobicContact CD1-CD2 3.41Å; L270-Y312 VanDerWaalsContact CD1-CD2 3.41Å; L270-Y312 HydrophobicContact CD1-CE2 3.35Å; L270-Y312 HydrophobicContact CG-CD2 4.45Å; V271-Y312 PolarHBondContact O-N 3.34Å; V272-Y312 CarbonylContact C-O 3.56Å; V272-Y312 WeakPolarHBondContact CA-O 3.35Å; V273-Y312 VanDerWaalsContact CG2-O 3.28Å; V273-Y312 WeakPolarHBondContact CG2-O 3.34Å; V273-Y312 PolarHBondContact N-O 3.02Å; L287-Y312 HydrophobicContact CD1-CD1 4.31Å; L287-Y312 HydrophobicContact CD1-CG 4.32Å; L287-Y312 HydrophobicContact CD2-CD1 4.12Å; L287-Y312 HydrophobicContact CG-CD1 4.25Å; R288-Y312 CarbonylContact O-C 3.52Å; R288-Y312 VanDerWaalsContact O-CA 3.25Å; R288-Y312 WeakPolarHBondContact O-CA 3.44Å; Y302-Y312 HydrophobicContact CD1-CD1 4.21Å; Y302-Y312 AromaticContact CD1-CE1 3.59Å; Y302-Y312 HydrophobicContact CD1-CE1 3.59Å; Y302-Y312 HydrophobicContact CD2-CE1 4.26Å; Y302-Y312 AromaticContact CE1-CE1 3.47Å; Y302-Y312 HydrophobicContact CE1-CE1 3.47Å; Y302-Y312 VanDerWaalsContact CE1-CE1 3.47Å; Y302-Y312 HydrophobicContact CE2-CE1 4.18Å; Y302-Y312 HydrophobicContact CG-CD1 4.37Å; Y302-Y312 AromaticContact CG-CE1 3.96Å; Y302-Y312 HydrophobicContact CG-CE1 3.96Å; Y302-Y312 AromaticContact CZ-CE1 3.78Å; L306-Y312 HydrophobicContact CD1-CE2 3.92Å; Q307-Y312 PolarHBondContact N-OH 3.19Å; T310-Y312 HydrophobicContact CG2-CD1 4.32Å; T310-Y312 HydrophobicContact CG2-CD2 4.48Å; T310-Y312 HydrophobicContact CG2-CE1 3.78Å; T310-Y312 HydrophobicContact CG2-CE2 3.97Å
313S96.9Very high89.3Confident6 Ų647.9 Ų47.94%0.04227%0.273CS..EExtended strand (participates in β ladder)trans-131.2138.4176.3170.30000109.9V273 D274 R288 L297V273-S313 CarbonylContact O-C 3.58Å; V273-S313 VanDerWaalsContact O-CA 3.29Å; V273-S313 WeakPolarHBondContact O-CA 3.49Å; D274-S313 WeakPolarHBondContact CB-OG 3.45Å; D274-S313 PolarHBondContact OD2-OG 2.89Å; R288-S313 PolarHBondContact N-O 3.14Å; R288-S313 PolarHBondContact O-N 2.92Å; L297-S313 VanDerWaalsContact CD2-CB 3.4Å
314G95.9Very high89.9Confident3 Ų341.5 Ų41.53%0.03123%0.234CC..SBendtrans74.5-127.7-178.400000113V272 V273 T285V272-G314 VanDerWaalsContact CG1-O 3.24Å; V272-G314 WeakPolarHBondContact CG1-O 3.5Å; V273-G314 PolarHBondContact O-N 3.02Å; T285-G314 WeakPolarHBondContact OG1-CA 3.3Å
315G94.8Very high90.6Very high1 Ų146.5 Ų46.51%0.0125%0.253CS..  trans73.8-162-177.800000113.9G284 T285G284-G315 CarbonylContact C-O 3.56Å; G284-G315 VanDerWaalsContact CA-O 3.25Å; G284-G315 WeakPolarHBondContact CA-O 3.4Å; T285-G315 PolarHBondContact N-O 3.21Å; T285-G315 CarbonylContact O-C 3.58Å; T285-G315 WeakPolarHBondContact O-CA 3.41Å; T285-G315 PolarHBondContact O-N 3.3Å; T285-G315 PolarHBondContact OG1-N 2.8Å
316S96.2Very high91.1Very high11 Ų1140.3 Ų40.38%0.07722%0.22CC..  trans-138.7167.7176.9710000110.9F280 D318 I319 V320F280-S316 CarbonylContact O-C 3.57Å; F280-S316 WeakPolarHBondContact O-CA 3.15Å; S316-D318 PolarHBondContact O-N 3.28Å; S316-D318 PolarHBondContact OG-N 3.41Å; S316-I319 PolarHBondContact O-N 3.05Å; S316-I319 PolarHBondContact OG-N 2.88Å; S316-V320 PolarHBondContact O-N 2.87Å
317S94.3Very high91.5Very high0 Ų040.9 Ų40.90%023%0.229CC..Hα-helixtrans-59.7-32.8173.353.80000113F280 V320 S321 Q349F280-S317 PolarHBondContact O-N 3.04Å; S317-V320 PolarHBondContact O-N 3.31Å; S317-S321 PolarHBondContact O-N 3.14Å; S317-Q349 VanDerWaalsContact OG-CD 3.28Å; S317-Q349 WeakPolarHBondContact OG-CG 3.49Å; S317-Q349 PolarHBondContact OG-NE2 3.43Å
318D92.8Very high91.8Very high72 Ų7236.7 Ų36.739%0.38522%0.215SC..Hα-helixtrans-66.6-43.9-179.7-57.1-17.1000110.1S316 V320 S321 D322 Q349S316-D318 PolarHBondContact O-N 3.28Å; S316-D318 PolarHBondContact OG-N 3.41Å; D318-V320 VanDerWaalsContact C-N 3.29Å; D318-V320 PolarHBondContact O-N 2.98Å; D318-S321 CarbonylContact O-C 3.6Å; D318-S321 WeakPolarHBondContact O-CA 3.4Å; D318-S321 VanDerWaalsContact O-CB 3.31Å; D318-S321 WeakPolarHBondContact O-CB 3.21Å; D318-S321 PolarHBondContact O-N 3.21Å; D318-S321 VanDerWaalsContact O-N 3.1Å; D318-D322 VanDerWaalsContact O-CG 3.28Å; D318-D322 PolarHBondContact O-N 3.34Å; D318-Q349 PolarHBondContact OD1-NE2 3.43Å; D318-Q349 PolarHBondContact OD1-OE1 3.03Å
319I91.9Very high92.6Very high48 Ų4837.2 Ų37.225%0.24622%0.215CC..Hα-helixtrans-59.9-40.1175-66.5175000111.2L287 S316 D322 L323L287-I319 HydrophobicContact CB-CD1 4.15Å; L287-I319 HydrophobicContact CD1-CG2 4.13Å; L287-I319 HydrophobicContact CD2-CG2 3.76Å; L287-I319 HydrophobicContact CG-CG2 4.41Å; S316-I319 PolarHBondContact O-N 3.05Å; S316-I319 PolarHBondContact OG-N 2.88Å; I319-D322 PolarHBondContact O-N 2.97Å; I319-L323 HydrophobicContact CG2-CD1 3.85Å; I319-L323 HydrophobicContact CG2-CG 4.27Å; I319-L323 WeakPolarHBondContact O-CB 3.44Å; I319-L323 VanDerWaalsContact O-CG 3.25Å; I319-L323 WeakPolarHBondContact O-CG 3.39Å; I319-L323 PolarHBondContact O-N 3.07Å
320V90.5Very high93.5Very high2 Ų237.8 Ų37.81%0.01221%0.21CC..Hα-helixtrans-64.1-43.3175.9168.30000111.2F233 L270 V272 F280 S316 S317 D318 L324F233-V320 HydrophobicContact CD1-CG1 4.28Å; F233-V320 HydrophobicContact CD2-CG1 4.02Å; F233-V320 HydrophobicContact CE1-CG1 4.26Å; F233-V320 HydrophobicContact CE2-CG1 4Å; F233-V320 HydrophobicContact CG-CG1 4.15Å; F233-V320 HydrophobicContact CZ-CG1 4.11Å; L270-V320 HydrophobicContact CD2-CB 4.06Å; L270-V320 HydrophobicContact CD2-CG1 3.74Å; L270-V320 HydrophobicContact CD2-CG2 3.71Å; V272-V320 HydrophobicContact CG2-CG2 3.95Å; F280-V320 HydrophobicContact CE2-CG2 4.39Å; F280-V320 HydrophobicContact CZ-CG2 3.63Å; S316-V320 PolarHBondContact O-N 2.87Å; S317-V320 PolarHBondContact O-N 3.31Å; D318-V320 VanDerWaalsContact C-N 3.29Å; D318-V320 PolarHBondContact O-N 2.98Å; V320-L324 HydrophobicContact CG1-CD1 3.82Å; V320-L324 WeakPolarHBondContact O-CB 3.17Å; V320-L324 PolarHBondContact O-N 2.99Å
321S93Very high93.9Very high15 Ų1536.8 Ų36.811%0.10520%0.203CC..Hα-helixtrans-59.6-44.2174.9-95.30000112.2S317 D318 D325 V326S317-S321 PolarHBondContact O-N 3.14Å; D318-S321 CarbonylContact O-C 3.6Å; D318-S321 WeakPolarHBondContact O-CA 3.4Å; D318-S321 VanDerWaalsContact O-CB 3.31Å; D318-S321 WeakPolarHBondContact O-CB 3.21Å; D318-S321 PolarHBondContact O-N 3.21Å; D318-S321 VanDerWaalsContact O-N 3.1Å; S321-D325 WeakPolarHBondContact O-CA 3.45Å; S321-D325 PolarHBondContact O-N 3.46Å; S321-V326 WeakPolarHBondContact CA-O 3.41Å; S321-V326 WeakPolarHBondContact CB-O 3.46Å; S321-V326 PolarHBondContact O-N 3.29Å; S321-V326 PolarHBondContact OG-O 3.06Å
322D92.5Very high94.1Very high128 Ų12836.7 Ų36.768%0.68420%0.203SC*.Hα-helixtrans-66.4-48.4179-67.1-19.1000111.7D318 I319 L324 D325D318-D322 VanDerWaalsContact O-CG 3.28Å; D318-D322 PolarHBondContact O-N 3.34Å; I319-D322 PolarHBondContact O-N 2.97Å; D322-L324 VanDerWaalsContact C-N 3.26Å; D322-L324 PolarHBondContact O-N 3.48Å; D322-D325 PolarHBondContact O-N 3.07Å
323L92.1Very high94.2Very high35 Ų3536.7 Ų36.718%0.18320%0.203CC..Hα-helixtrans-63-33.9-179.7-73.1174000112.6L270 L287 L306 I319L270-L323 HydrophobicContact CD1-CD1 4.01Å; L287-L323 HydrophobicContact CD2-CD1 4.47Å; L306-L323 HydrophobicContact CB-CB 4.47Å; L306-L323 HydrophobicContact CB-CD2 4.14Å; L306-L323 WeakPolarHBondContact CD2-O 3.46Å; I319-L323 HydrophobicContact CG2-CD1 3.85Å; I319-L323 HydrophobicContact CG2-CG 4.27Å; I319-L323 WeakPolarHBondContact O-CB 3.44Å; I319-L323 VanDerWaalsContact O-CG 3.25Å; I319-L323 WeakPolarHBondContact O-CG 3.39Å; I319-L323 PolarHBondContact O-N 3.07Å
324L93.6Very high94.3Very high1 Ų136.4 Ų36.41%0.00520%0.201CC..Hα-helixtrans-95.5-1.2-179.7-68.7172.3000113.2K231 F233 D269 L270 L306 V320 D322 V326K231-L324 HydrophobicContact CD-CB 4.42Å; K231-L324 HydrophobicContact CD-CD2 4.21Å; K231-L324 WeakPolarHBondContact CD-O 3.46Å; K231-L324 PolarHBondContact NZ-O 3.16Å; F233-L324 HydrophobicContact CB-CD1 3.87Å; F233-L324 HydrophobicContact CD1-CD1 3.72Å; F233-L324 HydrophobicContact CG-CD1 4.02Å; D269-L324 HydrophobicContact CB-CD2 4.17Å; L270-L324 HydrophobicContact CB-CD1 4.11Å; L270-L324 HydrophobicContact CB-CD2 3.92Å; L270-L324 HydrophobicContact CB-CG 4.19Å; L270-L324 HydrophobicContact CD2-CD1 3.97Å; L270-L324 HydrophobicContact CD2-CG 4.14Å; L306-L324 HydrophobicContact CD2-CD2 4.02Å; V320-L324 HydrophobicContact CG1-CD1 3.82Å; V320-L324 WeakPolarHBondContact O-CB 3.17Å; V320-L324 PolarHBondContact O-N 2.99Å; D322-L324 VanDerWaalsContact C-N 3.26Å; D322-L324 PolarHBondContact O-N 3.48Å; L324-V326 VanDerWaalsContact C-N 3.31Å; L324-V326 HydrophobicContact CB-CG2 3.65Å; L324-V326 PolarHBondContact O-N 2.87Å
325D94.3Very high94.4Very high139 Ų13936.3 Ų36.374%0.74320%0.199SC*.THydrogen-bonded Turntrans48.552.3-176.5-171.536.2000111.9S321 D322S321-D325 WeakPolarHBondContact O-CA 3.45Å; S321-D325 PolarHBondContact O-N 3.46Å; D322-D325 PolarHBondContact O-N 3.07Å
326V94.4Very high94.5Very high15 Ų1536.5 Ų36.59%0.09120%0.2CC..  trans-139.8146.3-179.2-70.60000111.4K34 C35 S321 L324 I331K34-V326 HydrophobicContact CB-CG1 4.39Å; C35-V326 HydrophobicContact CB-CB 4.33Å; C35-V326 HydrophobicContact CB-CG1 4.08Å; C35-V326 HydrophobicContact CB-CG2 4.03Å; S321-V326 WeakPolarHBondContact CA-O 3.41Å; S321-V326 WeakPolarHBondContact CB-O 3.46Å; S321-V326 PolarHBondContact O-N 3.29Å; S321-V326 PolarHBondContact OG-O 3.06Å; L324-V326 VanDerWaalsContact C-N 3.31Å; L324-V326 HydrophobicContact CB-CG2 3.65Å; L324-V326 PolarHBondContact O-N 2.87Å; V326-I331 HydrophobicContact CB-CD1 4.48Å; V326-I331 HydrophobicContact CB-CG1 4.25Å; V326-I331 HydrophobicContact CG2-CD1 3.86Å; V326-I331 HydrophobicContact CG2-CG1 3.94Å
327S90.8Very high94.6Very high72 Ų7237.9 Ų37.950%0.50321%0.205SC..  trans-121.9144.7-172.776.40000112.1K329 D330S327-K329 PolarHBondContact O-N 2.99Å; S327-D330 PolarHBondContact N-OD2 3.49Å; S327-D330 WeakPolarHBondContact O-CB 3.07Å; S327-D330 VanDerWaalsContact O-CG 3.3Å; S327-D330 PolarHBondContact O-N 3.19Å; S327-D330 VanDerWaalsContact O-OD2 3.11Å; S327-D330 PolarHBondContact OG-OD2 3.36Å
328G88.9Confident94.6Very high20 Ų2037.9 Ų37.921%0.20621%0.205CC..G310 helixtrans31.4-98.6160.200000116.5D330 I331 W351G328-D330 VanDerWaalsContact C-N 3.3Å; G328-D330 PolarHBondContact O-N 3.32Å; G328-I331 PolarHBondContact O-N 2.94Å; G328-W351 WeakPolarHBondContact O-CA 3.35Å
329K93.8Very high94.5Very high152 Ų15238 Ų3866%0.66120%0.202SC*.G310 helixtrans-74.6-12.4-173.1-66.5177.8-176.9171.10114.9S327 I331S327-K329 PolarHBondContact O-N 2.99Å; K329-I331 PolarHBondContact O-N 2.94Å
330D96.5Very high94.4Very high51 Ų5135.7 Ų35.727%0.27319%0.191SC..G310 helixtrans-74.4-15.3174.9-53-38.9000111.5I33 K34 C35 S327 G328I33-D330 CarbonylContact C-O 3.51Å; K34-D330 HydrophobicContact CB-CB 4.14Å; K34-D330 HydrophobicContact CG-CB 4.18Å; K34-D330 PolarHBondContact N-O 2.86Å; C35-D330 PolarHBondContact N-O 3.14Å; S327-D330 PolarHBondContact N-OD2 3.49Å; S327-D330 WeakPolarHBondContact O-CB 3.07Å; S327-D330 VanDerWaalsContact O-CG 3.3Å; S327-D330 PolarHBondContact O-N 3.19Å; S327-D330 VanDerWaalsContact O-OD2 3.11Å; S327-D330 PolarHBondContact OG-OD2 3.36Å; G328-D330 VanDerWaalsContact C-N 3.3Å; G328-D330 PolarHBondContact O-N 3.32Å
331I98.1Very high94.6Very high0 Ų035.6 Ų35.60%019%0.19CC..EExtended strand (participates in β ladder)trans-102.1124.6-175-55.7171.7000109.9C35 F233 V326 G328 K329 W351 K352C35-I331 HydrophobicContact CB-CG1 4.12Å; C35-I331 WeakPolarHBondContact O-CA 3.27Å; F233-I331 HydrophobicContact CE1-CG2 3.9Å; F233-I331 HydrophobicContact CZ-CG2 4.14Å; V326-I331 HydrophobicContact CB-CD1 4.48Å; V326-I331 HydrophobicContact CB-CG1 4.25Å; V326-I331 HydrophobicContact CG2-CD1 3.86Å; V326-I331 HydrophobicContact CG2-CG1 3.94Å; G328-I331 PolarHBondContact O-N 2.94Å; K329-I331 PolarHBondContact O-N 2.94Å; I331-W351 HydrophobicContact CB-CD2 4.25Å; I331-W351 HydrophobicContact CB-CG 4.29Å; I331-W351 HydrophobicContact CD1-CD2 4.27Å; I331-W351 HydrophobicContact CD1-CH2 4.4Å; I331-W351 HydrophobicContact CD1-CZ2 3.61Å; I331-W351 HydrophobicContact CG2-CD2 3.91Å; I331-W351 HydrophobicContact CG2-CE3 3.94Å; I331-W351 HydrophobicContact CG2-CG 4.37Å; I331-W351 HydrophobicContact CG2-CH2 4.46Å; I331-W351 HydrophobicContact CG2-CZ2 4.49Å; I331-W351 HydrophobicContact CG2-CZ3 4.19Å; I331-K352 WeakPolarHBondContact O-CA 3.5Å; I331-K352 VanDerWaalsContact O-CB 3.3Å; I331-K352 WeakPolarHBondContact O-CB 3.29Å; I331-K352 PolarHBondContact O-N 3.08Å
332L98.6Very high94.8Very high0 Ų034.9 Ų34.90%019%0.185CC..EExtended strand (participates in β ladder)trans-100.6108.6162.2-178.961.7000109L28 L30 I33 C35 Y36 G37 I334 K352 F354L28-L332 HydrophobicContact CD1-CD1 4.04Å; L30-L332 HydrophobicContact CD2-CD2 4.33Å; I33-L332 HydrophobicContact CD1-CB 4.21Å; I33-L332 HydrophobicContact CG1-CB 4.28Å; I33-L332 HydrophobicContact CG2-CB 3.67Å; C35-L332 PolarHBondContact O-N 3.36Å; Y36-L332 WeakPolarHBondContact CA-O 3.2Å; Y36-L332 HydrophobicContact CD1-CB 4.34Å; Y36-L332 HydrophobicContact CD1-CD2 4.06Å; Y36-L332 HydrophobicContact CE1-CB 4.49Å; Y36-L332 HydrophobicContact CE1-CD2 3.77Å; G37-L332 PolarHBondContact N-O 2.84Å; L332-I334 HydrophobicContact CG-CD1 4.23Å; L332-I334 HydrophobicContact CG-CG1 4.29Å; L332-I334 WeakPolarHBondContact O-CD1 3.46Å; L332-K352 WeakPolarHBondContact CA-O 3.46Å; L332-K352 HydrophobicContact CD1-CB 3.88Å; L332-F354 HydrophobicContact CD1-CB 4.1Å; L332-F354 HydrophobicContact CG-CB 4.45Å
333Y98.5Very high94.9Very high0 Ų029.5 Ų29.50%016%0.156CC..EExtended strand (participates in β ladder)trans-95.2127.8175.8-166.4-113.4000111.2G37 F233 A235 K277 F281 D341 W351 K352 T353 F354G37-Y333 CarbonylContact O-C 3.51Å; G37-Y333 WeakPolarHBondContact O-CA 3.29Å; G37-Y333 WeakPolarHBondContact O-CD2 3.41Å; F233-Y333 HydrophobicContact CE2-CD2 4Å; F233-Y333 AromaticContact CE2-CE2 3.85Å; F233-Y333 HydrophobicContact CE2-CE2 3.85Å; F233-Y333 AromaticContact CZ-CD2 3.84Å; F233-Y333 HydrophobicContact CZ-CD2 3.84Å; F233-Y333 HydrophobicContact CZ-CE2 4.19Å; A235-Y333 HydrophobicContact CB-CE2 4.15Å; A235-Y333 PolarHBondContact O-OH 2.92Å; K277-Y333 PolarHBondContact NZ-OH 3.44Å; K277-Y333 VanDerWaalsContact NZ-OH 3.08Å; F281-Y333 HydrophobicContact CE2-CE1 4.48Å; F281-Y333 HydrophobicContact CZ-CD1 4.07Å; F281-Y333 AromaticContact CZ-CE1 3.69Å; F281-Y333 HydrophobicContact CZ-CE1 3.69Å; Y333-D341 HydrophobicContact CD1-CB 4.18Å; Y333-D341 HydrophobicContact CE1-CB 3.72Å; Y333-W351 HydrophobicContact CD1-CE3 4.49Å; Y333-W351 HydrophobicContact CD2-CE3 4.15Å; Y333-W351 AromaticContact CD2-CZ3 3.7Å; Y333-W351 HydrophobicContact CD2-CZ3 3.7Å; Y333-W351 HydrophobicContact CE2-CZ3 4.35Å; Y333-W351 AromaticContact CG-CE3 3.82Å; Y333-W351 HydrophobicContact CG-CE3 3.82Å; Y333-W351 AromaticContact CG-CZ3 3.83Å; Y333-W351 HydrophobicContact CG-CZ3 3.83Å; Y333-K352 PolarHBondContact N-O 3.47Å; Y333-T353 WeakPolarHBondContact O-CA 3.3Å; Y333-F354 PolarHBondContact O-N 3.06Å
334I98.8Very high94.9Very high0 Ų029.9 Ų29.90%016%0.156CC..EExtended strand (participates in β ladder)trans-113.7119.4-174.4-56.5112.8000108.4Y36 G37 F38 D39 T43 L332 F354 V356 C450Y36-I334 HydrophobicContact CD1-CD1 4.1Å; G37-I334 WeakPolarHBondContact O-CD1 3.48Å; G37-I334 PolarHBondContact O-N 3.35Å; F38-I334 HydrophobicContact CD1-CB 4Å; F38-I334 HydrophobicContact CD1-CD1 4.12Å; F38-I334 HydrophobicContact CD1-CG2 4.22Å; F38-I334 HydrophobicContact CD2-CD1 4.43Å; F38-I334 HydrophobicContact CE1-CB 4.22Å; F38-I334 HydrophobicContact CE1-CD1 3.77Å; F38-I334 HydrophobicContact CE1-CG1 4.35Å; F38-I334 HydrophobicContact CE1-CG2 4.31Å; F38-I334 HydrophobicContact CE2-CD1 4.09Å; F38-I334 HydrophobicContact CG-CD1 4.45Å; F38-I334 HydrophobicContact CZ-CD1 3.76Å; D39-I334 PolarHBondContact N-O 3.19Å; T43-I334 HydrophobicContact CG2-CG2 3.86Å; T43-I334 WeakPolarHBondContact CG2-O 3.28Å; L332-I334 HydrophobicContact CG-CD1 4.23Å; L332-I334 HydrophobicContact CG-CG1 4.29Å; L332-I334 WeakPolarHBondContact O-CD1 3.46Å; I334-F354 WeakPolarHBondContact CA-O 3.29Å; I334-F354 HydrophobicContact CB-CB 4.23Å; I334-F354 HydrophobicContact CG1-CB 3.64Å; I334-F354 HydrophobicContact CG1-CG 4.19Å; I334-F354 HydrophobicContact CG2-CB 4.23Å; I334-F354 HydrophobicContact CG2-CD1 3.88Å; I334-F354 HydrophobicContact CG2-CG 4.26Å; I334-V356 HydrophobicContact CG2-CG2 3.82Å; I334-C450 HydrophobicContact CG2-CB 3.69Å
335G98.3Very high94.9Very high0 Ų029.8 Ų29.80%016%0.156CC..EExtended strand (participates in β ladder)trans-158.1167.3-178.400000112.2T43 F354 L355 V356T43-G335 WeakPolarHBondContact OG1-CA 3.45Å; G335-F354 PolarHBondContact N-O 2.86Å; G335-F354 VanDerWaalsContact N-O 3.17Å; G335-L355 WeakPolarHBondContact O-CA 3.47Å; G335-V356 PolarHBondContact O-N 3.44Å
336D97.8Very high94.8Very high5 Ų525.4 Ų25.43%0.02713%0.131CC..SBendtrans-101.3-21.1179.375.7-67.6000112.9T43 R85 I338 D341 L355 V356T43-D336 PolarHBondContact OG1-N 3.36Å; T43-D336 PolarHBondContact OG1-OD1 3.05Å; R85-D336 PolarHBondContact NH1-O 3.02Å; D336-I338 PolarHBondContact O-N 2.86Å; D336-I338 VanDerWaalsContact O-N 3.13Å; D336-D341 PolarHBondContact N-OD2 3.38Å; D336-L355 WeakPolarHBondContact O-CD1 3.48Å; D336-V356 WeakPolarHBondContact CA-O 3.4Å; D336-V356 HydrophobicContact CB-CB 4.44Å
337H96.4Very high94.7Very high41 Ų4131 Ų3119%0.1915%0.153CC..  trans-82100-176.4-168.3-3000111.1T142 F339 G340 D341 I342T142-H337 HydrophobicContact CG2-CB 4.35Å; H337-F339 PolarHBondContact ND1-N 3.27Å; H337-F339 PolarHBondContact O-N 3.2Å; H337-G340 PolarHBondContact ND1-N 2.99Å; H337-G340 PolarHBondContact O-N 3.12Å; H337-D341 HydrophobicContact CB-CB 4.41Å; H337-D341 VanDerWaalsContact CB-OD2 3.25Å; H337-D341 WeakPolarHBondContact CB-OD2 3.08Å; H337-D341 PolarHBondContact N-OD2 2.87Å; H337-D341 WeakPolarHBondContact O-CB 3.28Å; H337-D341 PolarHBondContact O-N 3.46Å; H337-I342 PolarHBondContact O-N 2.9Å
338I94.9Very high94.6Very high0 Ų033.9 Ų33.90%015%0.153CC..Iπ-helixtrans-51.1-36.5-178.4-172.663.6000114N141 D336 I342 L343 L355 F435 Q438 L439N141-I338 HydrophobicContact CB-CG2 4.23Å; D336-I338 PolarHBondContact O-N 2.86Å; D336-I338 VanDerWaalsContact O-N 3.13Å; I338-I342 HydrophobicContact CD1-CB 4.44Å; I338-I342 HydrophobicContact CD1-CG2 4.38Å; I338-L343 VanDerWaalsContact O-CB 3.29Å; I338-L343 WeakPolarHBondContact O-CB 3.25Å; I338-L343 PolarHBondContact O-N 3.13Å; I338-L355 HydrophobicContact CB-CD1 4.42Å; I338-L355 HydrophobicContact CD1-CD1 4.31Å; I338-L355 HydrophobicContact CD1-CD2 3.79Å; I338-F435 HydrophobicContact CB-CE2 3.97Å; I338-F435 HydrophobicContact CG2-CD2 4.08Å; I338-F435 HydrophobicContact CG2-CE2 3.77Å; I338-Q438 HydrophobicContact CD1-CB 4.24Å; I338-Q438 HydrophobicContact CG1-CB 3.83Å; I338-L439 HydrophobicContact CD1-CB 4.47Å
339F91.6Very high94.6Very high73 Ų7335.1 Ų35.132%0.3215%0.154SC..Iπ-helixtrans-89.2-54.7177.8-176.2-97.3000112.2P278 H337 L343 K344P278-F339 HydrophobicContact CB-CE1 4.43Å; P278-F339 HydrophobicContact CG-CE1 4.07Å; H337-F339 PolarHBondContact ND1-N 3.27Å; H337-F339 PolarHBondContact O-N 3.2Å; F339-L343 HydrophobicContact CD2-CD1 4.05Å; F339-L343 HydrophobicContact CD2-CD2 4.36Å; F339-L343 HydrophobicContact CE2-CD2 4.35Å; F339-K344 VanDerWaalsContact CE1-CE 3.49Å; F339-K344 HydrophobicContact CE1-CG 4.48Å; F339-K344 WeakPolarHBondContact O-CG 3.4Å; F339-K344 PolarHBondContact O-N 3.41Å
340G89.7Confident94.6Very high0 Ų029.5 Ų29.50%014%0.139CC..Iπ-helixtrans-63.9-45.3-172.700000113.3F281 H337F281-G340 VanDerWaalsContact CD2-O 3.25Å; F281-G340 WeakPolarHBondContact CD2-O 3.27Å; F281-G340 WeakPolarHBondContact CE2-O 3.36Å; H337-G340 PolarHBondContact ND1-N 2.99Å; H337-G340 PolarHBondContact O-N 3.12Å
341D94.4Very high94.6Very high1 Ų127 Ų271%0.00513%0.126CC..Iπ-helixtrans-95.9-50.1-174.7-60.6-34.8000111.8K277 Y333 D336 H337 S345K277-D341 VanDerWaalsContact CD-OD1 3.29Å; K277-D341 WeakPolarHBondContact CD-OD1 3.35Å; K277-D341 WeakPolarHBondContact CE-OD1 3.47Å; K277-D341 IonicContact NZ-OD1 3.25Å; K277-D341 PolarHBondContact NZ-OD1 3.28Å; Y333-D341 HydrophobicContact CD1-CB 4.18Å; Y333-D341 HydrophobicContact CE1-CB 3.72Å; D336-D341 PolarHBondContact N-OD2 3.38Å; H337-D341 HydrophobicContact CB-CB 4.41Å; H337-D341 VanDerWaalsContact CB-OD2 3.25Å; H337-D341 WeakPolarHBondContact CB-OD2 3.08Å; H337-D341 PolarHBondContact N-OD2 2.87Å; H337-D341 WeakPolarHBondContact O-CB 3.28Å; H337-D341 PolarHBondContact O-N 3.46Å; D341-S345 WeakPolarHBondContact O-CB 3.38Å; D341-S345 PolarHBondContact O-OG 3.4Å
342I96.8Very high94.6Very high0 Ų029.2 Ų29.20%014%0.135CC..Iπ-helixtrans-88-59.3-165.8-55.7-55.4000111.7H337 I338 K344 S345 K346 T353 F354 L355 A443H337-I342 PolarHBondContact O-N 2.9Å; I338-I342 HydrophobicContact CD1-CB 4.44Å; I338-I342 HydrophobicContact CD1-CG2 4.38Å; I342-K344 VanDerWaalsContact C-N 3.34Å; I342-K344 PolarHBondContact O-N 3.4Å; I342-S345 PolarHBondContact O-OG 3.29Å; I342-K346 WeakPolarHBondContact O-CB 3.44Å; I342-K346 PolarHBondContact O-N 2.85Å; I342-T353 HydrophobicContact CG2-CG2 4.12Å; I342-F354 WeakPolarHBondContact CD1-O 3.3Å; I342-L355 HydrophobicContact CD1-CB 4.35Å; I342-L355 HydrophobicContact CD1-CD1 4.43Å; I342-L355 HydrophobicContact CG1-CB 4.12Å; I342-L355 HydrophobicContact CG1-CD1 3.61Å; I342-L355 HydrophobicContact CG1-CG 4.43Å; I342-A443 HydrophobicContact CG2-CB 4.03Å
343L94.3Very high94.6Very high14 Ų1429.2 Ų29.27%0.07314%0.135CC..Iπ-helixtrans-60.3-44.2-176.5-176159.7000111.6I338 F339 K347 Y442I338-L343 VanDerWaalsContact O-CB 3.29Å; I338-L343 WeakPolarHBondContact O-CB 3.25Å; I338-L343 PolarHBondContact O-N 3.13Å; F339-L343 HydrophobicContact CD2-CD1 4.05Å; F339-L343 HydrophobicContact CD2-CD2 4.36Å; F339-L343 HydrophobicContact CE2-CD2 4.35Å; L343-K347 HydrophobicContact CD2-CD 3.86Å; L343-K347 HydrophobicContact CD2-CG 4.31Å; L343-K347 HydrophobicContact CG-CD 4.43Å; L343-K347 WeakPolarHBondContact O-CB 3.4Å; L343-K347 WeakPolarHBondContact O-CG 3.35Å; L343-K347 PolarHBondContact O-N 3.33Å; L343-Y442 HydrophobicContact CB-CD2 4.12Å; L343-Y442 HydrophobicContact CB-CG 4.19Å; L343-Y442 HydrophobicContact CD1-CD2 3.73Å; L343-Y442 HydrophobicContact CD1-CE1 4.49Å; L343-Y442 HydrophobicContact CD1-CE2 3.35Å; L343-Y442 HydrophobicContact CD1-CG 4.43Å; L343-Y442 HydrophobicContact CG-CD1 4.25Å; L343-Y442 HydrophobicContact CG-CD2 3.9Å; L343-Y442 HydrophobicContact CG-CE1 4.21Å; L343-Y442 HydrophobicContact CG-CE2 3.85Å; L343-Y442 HydrophobicContact CG-CG 4.1Å
344K92.9Very high94.6Very high43 Ų4329.2 Ų29.219%0.18714%0.135CC..Hα-helixtrans-73.5-44.8-174.7-69.6-78.8-177.5175.50112.4P278 F281 F339 I342 K346 K347 R348P278-K344 HydrophobicContact CB-CB 4.3Å; P278-K344 HydrophobicContact CB-CD 4.19Å; P278-K344 HydrophobicContact CB-CG 3.71Å; F281-K344 HydrophobicContact CB-CB 4.13Å; F281-K344 HydrophobicContact CD2-CB 3.96Å; F281-K344 HydrophobicContact CG-CB 4.31Å; F339-K344 VanDerWaalsContact CE1-CE 3.49Å; F339-K344 HydrophobicContact CE1-CG 4.48Å; F339-K344 WeakPolarHBondContact O-CG 3.4Å; F339-K344 PolarHBondContact O-N 3.41Å; I342-K344 VanDerWaalsContact C-N 3.34Å; I342-K344 PolarHBondContact O-N 3.4Å; K344-K346 VanDerWaalsContact C-N 3.31Å; K344-K346 PolarHBondContact O-N 2.93Å; K344-K347 PolarHBondContact O-N 3.33Å; K344-R348 WeakPolarHBondContact O-CB 3.34Å; K344-R348 PolarHBondContact O-N 2.92Å
345S92.2Very high94.6Very high0 Ų029.2 Ų29.20%014%0.135CC..Iπ-helixtrans-60.9-42.2173.666.80000111.5D341 I342 Q349 G350 W351D341-S345 WeakPolarHBondContact O-CB 3.38Å; D341-S345 PolarHBondContact O-OG 3.4Å; I342-S345 PolarHBondContact O-OG 3.29Å; S345-Q349 CarbonylContact O-C 3.56Å; S345-Q349 WeakPolarHBondContact O-CA 3.28Å; S345-Q349 WeakPolarHBondContact O-CB 3.21Å; S345-Q349 PolarHBondContact O-N 2.74Å; S345-G350 PolarHBondContact O-N 3.47Å; S345-G350 VanDerWaalsContact O-N 3.11Å; S345-W351 PolarHBondContact O-N 3.13Å
346K93.4Very high94.6Very high47 Ų4729.2 Ų29.220%0.20414%0.135CC..Iπ-helixtrans-62.1-51177.3-171.464.2160.4-171.50112.6I342 K344 G350 W351 T353 D444I342-K346 WeakPolarHBondContact O-CB 3.44Å; I342-K346 PolarHBondContact O-N 2.85Å; K344-K346 VanDerWaalsContact C-N 3.31Å; K344-K346 PolarHBondContact O-N 2.93Å; K346-G350 WeakPolarHBondContact O-CA 3.32Å; K346-G350 PolarHBondContact O-N 3.27Å; K346-W351 VanDerWaalsContact CD-O 3.3Å; K346-W351 WeakPolarHBondContact CD-O 3.44Å; K346-T353 HydrophobicContact CB-CG2 4.12Å; K346-T353 HydrophobicContact CD-CG2 4.31Å; K346-D444 IonicContact NZ-OD1 2.7Å; K346-D444 PolarHBondContact NZ-OD1 3.41Å; K346-D444 IonicContact NZ-OD2 2.9Å; K346-D444 PolarHBondContact NZ-OD2 2.97Å
347K91.8Very high94.6Very high131 Ų13129.1 Ų29.157%0.5713%0.134SC*.Iπ-helixtrans-76.4-37.8-173.5-77.4-163.7-179.8-174.90113.8L343 K344 Y442L343-K347 HydrophobicContact CD2-CD 3.86Å; L343-K347 HydrophobicContact CD2-CG 4.31Å; L343-K347 HydrophobicContact CG-CD 4.43Å; L343-K347 WeakPolarHBondContact O-CB 3.4Å; L343-K347 WeakPolarHBondContact O-CG 3.35Å; L343-K347 PolarHBondContact O-N 3.33Å; K344-K347 PolarHBondContact O-N 3.33Å; K347-Y442 HydrophobicContact CD-CE1 4.35Å; K347-Y442 VanDerWaalsContact CE-OH 3.23Å; K347-Y442 WeakPolarHBondContact CE-OH 3.33Å; K347-Y442 HydrophobicContact CG-CE1 4.29Å; K347-Y442 PolarHBondContact NZ-OH 3.11Å; K347-Y442 VanDerWaalsContact NZ-OH 3.1Å
348R89.1Confident94.7Very high134 Ų13428.4 Ų28.451%0.50613%0.134SC..Iπ-helixtrans-90.5-37-174.7-65.2-164.8170.4-143.43.6112.3F281 K344F281-R348 WeakPolarHBondContact O-CB 3.4Å; F281-R348 WeakPolarHBondContact O-CD 3.47Å; K344-R348 WeakPolarHBondContact O-CB 3.34Å; K344-R348 PolarHBondContact O-N 2.92Å
349Q89.7Confident94.7Very high46 Ų4630.3 Ų30.322%0.21514%0.142CC..Iπ-helixtrans-115.2-9-171.1-59.5-62.3-16.600113.9F281 S317 D318 S345 W351F281-Q349 HydrophobicContact CD1-CG 4.45Å; S317-Q349 VanDerWaalsContact OG-CD 3.28Å; S317-Q349 WeakPolarHBondContact OG-CG 3.49Å; S317-Q349 PolarHBondContact OG-NE2 3.43Å; D318-Q349 PolarHBondContact OD1-NE2 3.43Å; D318-Q349 PolarHBondContact OD1-OE1 3.03Å; S345-Q349 CarbonylContact O-C 3.56Å; S345-Q349 WeakPolarHBondContact O-CA 3.28Å; S345-Q349 WeakPolarHBondContact O-CB 3.21Å; S345-Q349 PolarHBondContact O-N 2.74Å; Q349-W351 VanDerWaalsContact CB-CD1 3.41Å; Q349-W351 HydrophobicContact CB-CD2 4.34Å; Q349-W351 HydrophobicContact CB-CG 3.98Å; Q349-W351 PolarHBondContact O-N 3.25Å
350G92.9Very high95Very high33 Ų3327.1 Ų27.134%0.3413%0.129SC..  trans67.419.5-179.300000113.8S345 K346S345-G350 PolarHBondContact O-N 3.47Å; S345-G350 VanDerWaalsContact O-N 3.11Å; K346-G350 WeakPolarHBondContact O-CA 3.32Å; K346-G350 PolarHBondContact O-N 3.27Å
351W96.4Very high95.1Very high0 Ų029.7 Ų29.70%015%0.145CC..  trans-62.2150.3179.7-708.8000111.5F233 F281 G328 I331 Y333 S345 K346 Q349F233-W351 HydrophobicContact CE2-CH2 4.24Å; F233-W351 HydrophobicContact CE2-CZ3 4.32Å; F233-W351 AromaticContact CZ-CH2 3.66Å; F233-W351 HydrophobicContact CZ-CH2 3.66Å; F233-W351 AromaticContact CZ-CZ3 3.7Å; F233-W351 HydrophobicContact CZ-CZ3 3.7Å; F281-W351 AromaticContact CE1-CE3 3.91Å; F281-W351 HydrophobicContact CE1-CE3 3.91Å; F281-W351 HydrophobicContact CE1-CH2 4.15Å; F281-W351 AromaticContact CE1-CZ3 3.62Å; F281-W351 HydrophobicContact CE1-CZ3 3.62Å; F281-W351 HydrophobicContact CZ-CZ3 4.42Å; G328-W351 WeakPolarHBondContact O-CA 3.35Å; I331-W351 HydrophobicContact CB-CD2 4.25Å; I331-W351 HydrophobicContact CB-CG 4.29Å; I331-W351 HydrophobicContact CD1-CD2 4.27Å; I331-W351 HydrophobicContact CD1-CH2 4.4Å; I331-W351 HydrophobicContact CD1-CZ2 3.61Å; I331-W351 HydrophobicContact CG2-CD2 3.91Å; I331-W351 HydrophobicContact CG2-CE3 3.94Å; I331-W351 HydrophobicContact CG2-CG 4.37Å; I331-W351 HydrophobicContact CG2-CH2 4.46Å; I331-W351 HydrophobicContact CG2-CZ2 4.49Å; I331-W351 HydrophobicContact CG2-CZ3 4.19Å; Y333-W351 HydrophobicContact CD1-CE3 4.49Å; Y333-W351 HydrophobicContact CD2-CE3 4.15Å; Y333-W351 AromaticContact CD2-CZ3 3.7Å; Y333-W351 HydrophobicContact CD2-CZ3 3.7Å; Y333-W351 HydrophobicContact CE2-CZ3 4.35Å; Y333-W351 AromaticContact CG-CE3 3.82Å; Y333-W351 HydrophobicContact CG-CE3 3.82Å; Y333-W351 AromaticContact CG-CZ3 3.83Å; Y333-W351 HydrophobicContact CG-CZ3 3.83Å; S345-W351 PolarHBondContact O-N 3.13Å; K346-W351 VanDerWaalsContact CD-O 3.3Å; K346-W351 WeakPolarHBondContact CD-O 3.44Å; Q349-W351 VanDerWaalsContact CB-CD1 3.41Å; Q349-W351 HydrophobicContact CB-CD2 4.34Å; Q349-W351 HydrophobicContact CB-CG 3.98Å; Q349-W351 PolarHBondContact O-N 3.25Å
352K98.1Very high95.1Very high46 Ų4635.1 Ų35.120%0.217%0.168CC..EExtended strand (participates in β ladder)trans-75.8145.9163.3-60.8-62.7-169.3164.20108.4L28 I33 I331 L332 Y333 D444L28-K352 HydrophobicContact CD1-CB 3.76Å; L28-K352 HydrophobicContact CD1-CD 4.06Å; L28-K352 HydrophobicContact CD1-CG 4Å; I33-K352 HydrophobicContact CD1-CB 4.25Å; I33-K352 HydrophobicContact CD1-CG 3.99Å; I331-K352 WeakPolarHBondContact O-CA 3.5Å; I331-K352 VanDerWaalsContact O-CB 3.3Å; I331-K352 WeakPolarHBondContact O-CB 3.29Å; I331-K352 PolarHBondContact O-N 3.08Å; L332-K352 WeakPolarHBondContact CA-O 3.46Å; L332-K352 HydrophobicContact CD1-CB 3.88Å; Y333-K352 PolarHBondContact N-O 3.47Å; K352-D444 WeakPolarHBondContact CA-OD2 3.43Å; K352-D444 WeakPolarHBondContact CD-OD2 3.45Å
353T98.5Very high95.1Very high0 Ų036.1 Ų36.10%017%0.173CC..EExtended strand (participates in β ladder)trans-133135.1-168.258.60000112.1Y333 I342 K346 Y442 A443 D444 L445Y333-T353 WeakPolarHBondContact O-CA 3.3Å; I342-T353 HydrophobicContact CG2-CG2 4.12Å; K346-T353 HydrophobicContact CB-CG2 4.12Å; K346-T353 HydrophobicContact CD-CG2 4.31Å; T353-Y442 PolarHBondContact OG1-O 3.15Å; T353-A443 WeakPolarHBondContact OG1-CA 3.36Å; T353-D444 PolarHBondContact N-OD2 2.79Å; T353-D444 WeakPolarHBondContact O-CB 3.46Å; T353-D444 PolarHBondContact O-N 3.09Å; T353-D444 PolarHBondContact OG1-N 3.18Å; T353-L445 PolarHBondContact O-N 3.38Å
354F98.8Very high95.1Very high0 Ų037.3 Ų37.30%018%0.179CC..EExtended strand (participates in β ladder)trans-117.6117.2169.2-171.5-66.3000108.6V22 L332 Y333 I334 G335 I342 V356 L445 L453V22-F354 HydrophobicContact CB-CE2 4.44Å; V22-F354 HydrophobicContact CG1-CD2 4.42Å; V22-F354 HydrophobicContact CG1-CE2 3.67Å; V22-F354 HydrophobicContact CG1-CZ 4.35Å; V22-F354 HydrophobicContact CG2-CE2 3.89Å; V22-F354 HydrophobicContact CG2-CZ 4.16Å; L332-F354 HydrophobicContact CD1-CB 4.1Å; L332-F354 HydrophobicContact CG-CB 4.45Å; Y333-F354 PolarHBondContact O-N 3.06Å; I334-F354 WeakPolarHBondContact CA-O 3.29Å; I334-F354 HydrophobicContact CB-CB 4.23Å; I334-F354 HydrophobicContact CG1-CB 3.64Å; I334-F354 HydrophobicContact CG1-CG 4.19Å; I334-F354 HydrophobicContact CG2-CB 4.23Å; I334-F354 HydrophobicContact CG2-CD1 3.88Å; I334-F354 HydrophobicContact CG2-CG 4.26Å; G335-F354 PolarHBondContact N-O 2.86Å; G335-F354 VanDerWaalsContact N-O 3.17Å; I342-F354 WeakPolarHBondContact CD1-O 3.3Å; F354-V356 HydrophobicContact CD1-CG2 4.15Å; F354-V356 HydrophobicContact CE1-CG2 4.1Å; F354-L445 CarbonylContact C-O 3.54Å; F354-L445 WeakPolarHBondContact CA-O 3.44Å; F354-L445 HydrophobicContact CB-CB 4.44Å; F354-L445 HydrophobicContact CD2-CB 3.71Å; F354-L445 HydrophobicContact CD2-CD1 4.09Å; F354-L445 HydrophobicContact CE2-CB 4.31Å; F354-L445 HydrophobicContact CG-CB 4.23Å; F354-L453 HydrophobicContact CD2-CD1 4.18Å; F354-L453 HydrophobicContact CD2-CD2 4.1Å; F354-L453 HydrophobicContact CD2-CG 4.25Å; F354-L453 HydrophobicContact CE2-CD1 4.09Å; F354-L453 HydrophobicContact CE2-CD2 3.73Å; F354-L453 HydrophobicContact CE2-CG 3.73Å; F354-L453 HydrophobicContact CZ-CG 4.41Å
355L98.8Very high95.1Very high0 Ų040.6 Ų40.60%020%0.195CC..EExtended strand (participates in β ladder)trans-91.4123.8175.4-18072.4000110.8G335 D336 I338 I342 V357 F435 L439 A443 L445 Y446 S447G335-L355 WeakPolarHBondContact O-CA 3.47Å; D336-L355 WeakPolarHBondContact O-CD1 3.48Å; I338-L355 HydrophobicContact CB-CD1 4.42Å; I338-L355 HydrophobicContact CD1-CD1 4.31Å; I338-L355 HydrophobicContact CD1-CD2 3.79Å; I342-L355 HydrophobicContact CD1-CB 4.35Å; I342-L355 HydrophobicContact CD1-CD1 4.43Å; I342-L355 HydrophobicContact CG1-CB 4.12Å; I342-L355 HydrophobicContact CG1-CD1 3.61Å; I342-L355 HydrophobicContact CG1-CG 4.43Å; L355-V357 HydrophobicContact CD2-CG2 3.48Å; L355-V357 VanDerWaalsContact CD2-CG2 3.48Å; L355-V357 HydrophobicContact CG-CG2 3.62Å; L355-F435 HydrophobicContact CD2-CZ 4.38Å; L355-L439 HydrophobicContact CD2-CB 4.2Å; L355-L439 HydrophobicContact CD2-CD1 3.74Å; L355-L439 HydrophobicContact CD2-CG 3.72Å; L355-A443 HydrophobicContact CB-CB 3.63Å; L355-A443 HydrophobicContact CD2-CB 4.34Å; L355-L445 PolarHBondContact N-O 2.89Å; L355-Y446 WeakPolarHBondContact O-CA 3.42Å; L355-Y446 WeakPolarHBondContact O-CB 3.2Å; L355-S447 PolarHBondContact O-N 3.45Å; L355-S447 VanDerWaalsContact O-N 3.09Å
356V98.6Very high95.2Very high0 Ų041.1 Ų41.10%020%0.198CC..EExtended strand (participates in β ladder)trans-84.9124.8167.9-177.50000108.7T43 M46 I334 G335 D336 F354 P358 C450T43-V356 HydrophobicContact CG2-CG2 4.02Å; M46-V356 HydrophobicContact CE-CG1 3.99Å; I334-V356 HydrophobicContact CG2-CG2 3.82Å; G335-V356 PolarHBondContact O-N 3.44Å; D336-V356 WeakPolarHBondContact CA-O 3.4Å; D336-V356 HydrophobicContact CB-CB 4.44Å; F354-V356 HydrophobicContact CD1-CG2 4.15Å; F354-V356 HydrophobicContact CE1-CG2 4.1Å; V356-P358 HydrophobicContact CG1-CG 4.22Å; V356-C450 HydrophobicContact CG2-CB 4.12Å
357V98.1Very high95.3Very high2 Ų242 Ų421%0.01220%0.201CC..  trans-126.783.6-179.7-172.90000108.6L355 E359 L360 L425 F435 L439 S447 S448L355-V357 HydrophobicContact CD2-CG2 3.48Å; L355-V357 VanDerWaalsContact CD2-CG2 3.48Å; L355-V357 HydrophobicContact CG-CG2 3.62Å; V357-E359 PolarHBondContact O-N 3.35Å; V357-E359 VanDerWaalsContact O-N 3.12Å; V357-L360 HydrophobicContact CB-CB 4.21Å; V357-L360 HydrophobicContact CG1-CB 4.21Å; V357-L360 WeakPolarHBondContact O-CB 3.41Å; V357-L360 PolarHBondContact O-N 2.65Å; V357-L425 HydrophobicContact CG1-CD2 3.72Å; V357-F435 HydrophobicContact CG1-CE1 4.5Å; V357-L439 HydrophobicContact CG2-CD1 3.97Å; V357-S447 PolarHBondContact N-O 3.42Å; V357-S448 WeakPolarHBondContact O-CA 3.33Å
358P96.8Very high95.4Very high27 Ų2740.7 Ų40.718%0.17520%0.196CC..THydrogen-bonded Turntrans-56.9-33.3-171.5-28.839.3000114M46 L143 V356 L360M46-P358 HydrophobicContact CE-CB 4.04Å; M46-P358 HydrophobicContact CE-CG 3.52Å; M46-P358 HydrophobicContact SD-CB 3.62Å; M46-P358 HydrophobicContact SD-CG 3.4Å; M46-P358 WeakPolarHBondContact SD-CG 3.38Å; L143-P358 HydrophobicContact CD1-CB 4.07Å; L143-P358 HydrophobicContact CD1-CG 3.63Å; V356-P358 HydrophobicContact CG1-CG 4.22Å; P358-L360 PolarHBondContact O-N 3.14Å; P358-L360 VanDerWaalsContact O-N 3.14Å
359E96.8Very high95.6Very high39 Ų3939.5 Ų39.518%0.18220%0.197CC..THydrogen-bonded Turntrans-65-17.3178.9-50.899.8127.100113R85 L143 V357 T361 K362 E363 L425R85-E359 WeakPolarHBondContact CB-OE1 3.44Å; R85-E359 IonicContact CZ-OE1 2.91Å; R85-E359 IonicContact CZ-OE2 2.73Å; R85-E359 IonicContact NE-OE1 3.83Å; R85-E359 PolarHBondContact NE-OE1 2.57Å; R85-E359 IonicContact NE-OE2 3.65Å; R85-E359 IonicContact NH2-OE1 2.99Å; R85-E359 PolarHBondContact NH2-OE1 3.16Å; R85-E359 IonicContact NH2-OE2 3.77Å; R85-E359 PolarHBondContact NH2-OE2 2.9Å; L143-E359 HydrophobicContact CD2-CG 4.21Å; L143-E359 WeakPolarHBondContact CD2-OE1 3.26Å; V357-E359 PolarHBondContact O-N 3.35Å; V357-E359 VanDerWaalsContact O-N 3.12Å; E359-T361 PolarHBondContact O-N 2.95Å; E359-K362 PolarHBondContact O-N 3.31Å; E359-K362 VanDerWaalsContact O-N 3.12Å; E359-E363 WeakPolarHBondContact O-CG 3.36Å; E359-E363 PolarHBondContact O-N 3.39Å; E359-L425 HydrophobicContact CB-CD2 4.45Å
360L96.7Very high95.8Very high7 Ų742.9 Ų42.94%0.03721%0.207CC..Hα-helixtrans-60.6-29.7-175.1-17064.1000112.6F23 V357 P358 E363 L364 L426 Y446F23-L360 HydrophobicContact CD2-CD2 3.89Å; F23-L360 HydrophobicContact CE2-CD2 3.71Å; V357-L360 HydrophobicContact CB-CB 4.21Å; V357-L360 HydrophobicContact CG1-CB 4.21Å; V357-L360 WeakPolarHBondContact O-CB 3.41Å; V357-L360 PolarHBondContact O-N 2.65Å; P358-L360 PolarHBondContact O-N 3.14Å; P358-L360 VanDerWaalsContact O-N 3.14Å; L360-E363 HydrophobicContact CD1-CB 4.43Å; L360-E363 PolarHBondContact O-N 3.33Å; L360-L364 HydrophobicContact CD1-CD1 4.26Å; L360-L364 HydrophobicContact CD1-CD2 4.44Å; L360-L364 HydrophobicContact CD1-CG 3.99Å; L360-L364 HydrophobicContact CD2-CD1 4.3Å; L360-L364 HydrophobicContact CG-CD1 3.76Å; L360-L364 HydrophobicContact CG-CG 4Å; L360-L364 VanDerWaalsContact O-CB 3.31Å; L360-L364 WeakPolarHBondContact O-CB 3.2Å; L360-L364 WeakPolarHBondContact O-CG 3.44Å; L360-L364 PolarHBondContact O-N 3.35Å; L360-L426 HydrophobicContact CD1-CD1 4.33Å; L360-Y446 HydrophobicContact CD2-CD2 3.89Å; L360-Y446 HydrophobicContact CD2-CE2 3.84Å
361T93.1Very high95.7Very high54 Ų5446.9 Ų46.933%0.33121%0.212SC..Hα-helixtrans-59.6-51.2175-57.10000111E359 Q365 S448E359-T361 PolarHBondContact O-N 2.95Å; T361-Q365 PolarHBondContact O-N 3.3Å; T361-S448 VanDerWaalsContact OG1-CB 3.27Å; T361-S448 WeakPolarHBondContact OG1-CB 3.14Å
362K93.8Very high95.7Very high115 Ų11553.1 Ų53.150%0.525%0.245SC..Hα-helixtrans-67.8-42.2176.8-177.1-175173-1650111.3E359 L364 Q365 V366 Y419E359-K362 PolarHBondContact O-N 3.31Å; E359-K362 VanDerWaalsContact O-N 3.12Å; K362-L364 VanDerWaalsContact C-N 3.33Å; K362-L364 PolarHBondContact O-N 2.86Å; K362-Q365 PolarHBondContact O-N 2.88Å; K362-V366 HydrophobicContact CG-CG2 4.37Å; K362-V366 WeakPolarHBondContact O-CG2 3.22Å; K362-V366 PolarHBondContact O-N 2.62Å; K362-Y419 PolarHBondContact NZ-O 3.29Å
363E95.7Very high95.5Very high21 Ų2151.9 Ų51.910%0.09824%0.241CC..Hα-helixtrans-58-44.6178.7-72.8-86.7166.100111.9E359 L360 V366 W367 Y419 S424 L425E359-E363 WeakPolarHBondContact O-CG 3.36Å; E359-E363 PolarHBondContact O-N 3.39Å; L360-E363 HydrophobicContact CD1-CB 4.43Å; L360-E363 PolarHBondContact O-N 3.33Å; E363-V366 PolarHBondContact O-N 3.15Å; E363-W367 WeakPolarHBondContact O-CB 3.4Å; E363-W367 PolarHBondContact O-N 3.5Å; E363-Y419 HydrophobicContact CB-CE1 4.45Å; E363-Y419 WeakPolarHBondContact OE2-CD1 3.18Å; E363-Y419 WeakPolarHBondContact OE2-CE1 3.35Å; E363-S424 WeakPolarHBondContact OE1-CA 3.38Å; E363-S424 PolarHBondContact OE1-OG 3.04Å; E363-S424 WeakPolarHBondContact OE2-CB 3.22Å; E363-S424 PolarHBondContact OE2-OG 3.26Å; E363-L425 WeakPolarHBondContact OE1-CB 3.27Å; E363-L425 PolarHBondContact OE1-N 3.47Å
364L94.5Very high95.3Very high39 Ų3953.8 Ų53.820%0.20425%0.249CC..Hα-helixtrans-67.8-39.5179.4-72.7169.2000112F18 F23 L360 K362 W367 E368F18-L364 HydrophobicContact CB-CD1 4.28Å; F23-L364 HydrophobicContact CE2-CD1 3.97Å; F23-L364 HydrophobicContact CZ-CD1 3.81Å; F23-L364 HydrophobicContact CZ-CD2 4.23Å; L360-L364 HydrophobicContact CD1-CD1 4.26Å; L360-L364 HydrophobicContact CD1-CD2 4.44Å; L360-L364 HydrophobicContact CD1-CG 3.99Å; L360-L364 HydrophobicContact CD2-CD1 4.3Å; L360-L364 HydrophobicContact CG-CD1 3.76Å; L360-L364 HydrophobicContact CG-CG 4Å; L360-L364 VanDerWaalsContact O-CB 3.31Å; L360-L364 WeakPolarHBondContact O-CB 3.2Å; L360-L364 WeakPolarHBondContact O-CG 3.44Å; L360-L364 PolarHBondContact O-N 3.35Å; K362-L364 VanDerWaalsContact C-N 3.33Å; K362-L364 PolarHBondContact O-N 2.86Å; L364-W367 PolarHBondContact O-N 2.98Å; L364-E368 PolarHBondContact O-N 2.82Å
365Q94Very high95.1Very high111 Ų11156.3 Ų56.352%0.51926%0.261SS..Hα-helixtrans-59.6-52.3174.3-176-172.2-12.900111T361 K362 W367 E368 E369T361-Q365 PolarHBondContact O-N 3.3Å; K362-Q365 PolarHBondContact O-N 2.88Å; Q365-W367 VanDerWaalsContact C-N 3.29Å; Q365-W367 PolarHBondContact O-N 2.74Å; Q365-E368 PolarHBondContact O-N 2.81Å; Q365-E369 WeakPolarHBondContact CG-OE1 3.07Å; Q365-E369 PolarHBondContact NE2-OE1 2.74Å; Q365-E369 WeakPolarHBondContact O-CG 3.32Å; Q365-E369 PolarHBondContact O-N 3.04Å
366V94.8Very high94.9Very high12 Ų1259.4 Ų59.47%0.07328%0.275CS..Hα-helixtrans-63.9-37.7179.51770000111.1K362 E363 E368 E369 R370 Y419K362-V366 HydrophobicContact CG-CG2 4.37Å; K362-V366 WeakPolarHBondContact O-CG2 3.22Å; K362-V366 PolarHBondContact O-N 2.62Å; E363-V366 PolarHBondContact O-N 3.15Å; V366-E368 PolarHBondContact O-N 2.58Å; V366-E369 PolarHBondContact O-N 2.88Å; V366-R370 HydrophobicContact CG1-CG 4.11Å; V366-R370 VanDerWaalsContact O-CB 3.27Å; V366-R370 WeakPolarHBondContact O-CB 3.37Å; V366-R370 WeakPolarHBondContact O-CG 3.33Å; V366-R370 PolarHBondContact O-N 2.65Å; V366-Y419 HydrophobicContact CB-CD1 4.03Å; V366-Y419 HydrophobicContact CB-CE1 3.73Å; V366-Y419 HydrophobicContact CG1-CD1 3.89Å; V366-Y419 HydrophobicContact CG1-CD2 3.95Å; V366-Y419 HydrophobicContact CG1-CE1 3.67Å; V366-Y419 HydrophobicContact CG1-CE2 3.72Å; V366-Y419 HydrophobicContact CG1-CG 4.02Å
367W94.3Very high94.7Very high66 Ų6659.4 Ų59.425%0.2528%0.276CS..Hα-helixtrans-58.5-46.7175.9177.6-93.9000111.8E363 L364 Q365 R370 R371 F374E363-W367 WeakPolarHBondContact O-CB 3.4Å; E363-W367 PolarHBondContact O-N 3.5Å; L364-W367 PolarHBondContact O-N 2.98Å; Q365-W367 VanDerWaalsContact C-N 3.29Å; Q365-W367 PolarHBondContact O-N 2.74Å; W367-R370 PolarHBondContact O-N 2.58Å; W367-R371 WeakPolarHBondContact O-CA 3.37Å; W367-R371 WeakPolarHBondContact O-CB 3.34Å; W367-R371 PolarHBondContact O-N 3.43Å; W367-F374 HydrophobicContact CH2-CB 4.16Å; W367-F374 AromaticContact CH2-CD1 3.5Å; W367-F374 HydrophobicContact CH2-CD1 3.5Å; W367-F374 AromaticContact CH2-CD2 3.71Å; W367-F374 HydrophobicContact CH2-CD2 3.71Å; W367-F374 AromaticContact CH2-CE1 3.75Å; W367-F374 HydrophobicContact CH2-CE1 3.75Å; W367-F374 AromaticContact CH2-CE2 3.95Å; W367-F374 HydrophobicContact CH2-CE2 3.95Å; W367-F374 AromaticContact CH2-CG 3.48Å; W367-F374 HydrophobicContact CH2-CG 3.48Å; W367-F374 VanDerWaalsContact CH2-CG 3.48Å; W367-F374 AromaticContact CH2-CZ 3.97Å; W367-F374 HydrophobicContact CH2-CZ 3.97Å; W367-F374 HydrophobicContact CZ2-CD1 4.04Å; W367-F374 HydrophobicContact CZ2-CE1 4.35Å; W367-F374 HydrophobicContact CZ2-CG 4.33Å; W367-F374 HydrophobicContact CZ3-CB 4.35Å; W367-F374 HydrophobicContact CZ3-CD1 4.4Å; W367-F374 AromaticContact CZ3-CD2 3.88Å; W367-F374 HydrophobicContact CZ3-CD2 3.88Å; W367-F374 HydrophobicContact CZ3-CE2 4.31Å; W367-F374 AromaticContact CZ3-CG 3.93Å; W367-F374 HydrophobicContact CZ3-CG 3.93Å
368E93.1Very high94.4Very high102 Ų10265.3 Ų65.348%0.47730%0.301SS..Hα-helixtrans-66.8-45178.9-167.660.9-15800111.4L364 Q365 V366 R370L364-E368 PolarHBondContact O-N 2.82Å; Q365-E368 PolarHBondContact O-N 2.81Å; V366-E368 PolarHBondContact O-N 2.58Å; E368-R370 VanDerWaalsContact C-N 3.28Å; E368-R370 PolarHBondContact O-N 3.35Å
369E93.6Very high94.2Very high110 Ų11070 Ų7051%0.51432%0.32SS..Hα-helixtrans-63.5-31.4178.6-71.2176.1-167.500113.3Q365 V366Q365-E369 WeakPolarHBondContact CG-OE1 3.07Å; Q365-E369 PolarHBondContact NE2-OE1 2.74Å; Q365-E369 WeakPolarHBondContact O-CG 3.32Å; Q365-E369 PolarHBondContact O-N 3.04Å; V366-E369 PolarHBondContact O-N 2.88Å
370R93.5Very high93.9Very high116 Ų11669.6 Ų69.644%0.43832%0.319SS..Hα-helixtrans-113.110.3-173.3-56.6-59.7-176-170.7-2.4113.9V366 W367 E368 N372 L373V366-R370 HydrophobicContact CG1-CG 4.11Å; V366-R370 VanDerWaalsContact O-CB 3.27Å; V366-R370 WeakPolarHBondContact O-CB 3.37Å; V366-R370 WeakPolarHBondContact O-CG 3.33Å; V366-R370 PolarHBondContact O-N 2.65Å; W367-R370 PolarHBondContact O-N 2.58Å; E368-R370 VanDerWaalsContact C-N 3.28Å; E368-R370 PolarHBondContact O-N 3.35Å; R370-N372 PolarHBondContact O-N 3.49Å; R370-N372 VanDerWaalsContact O-N 3.09Å; R370-L373 HydrophobicContact CB-CD1 4.33Å; R370-L373 WeakPolarHBondContact O-CB 3.12Å; R370-L373 PolarHBondContact O-N 2.94Å
371R92.8Very high93.5Very high117 Ų11772.9 Ų72.944%0.44234%0.337SS..Hα-helixtrans-51.3-38.1-177.9-174.2177.6174.9179.4-2.5113.3W367 L373 F374 E375W367-R371 WeakPolarHBondContact O-CA 3.37Å; W367-R371 WeakPolarHBondContact O-CB 3.34Å; W367-R371 PolarHBondContact O-N 3.43Å; R371-L373 VanDerWaalsContact C-N 3.25Å; R371-L373 PolarHBondContact O-N 2.98Å; R371-F374 WeakPolarHBondContact O-CA 3.38Å; R371-F374 WeakPolarHBondContact O-CB 3.44Å; R371-F374 PolarHBondContact O-N 3.42Å; R371-E375 HydrophobicContact CG-CG 4.28Å; R371-E375 IonicContact CZ-OE1 3.77Å; R371-E375 IonicContact NE-OE1 2.63Å; R371-E375 PolarHBondContact NE-OE1 3.22Å; R371-E375 IonicContact NH2-OE1 3.14Å; R371-E375 PolarHBondContact O-N 3.12Å
372N95.4Very high93.3Very high131 Ų13176 Ų7670%0.70135%0.346SS*.Hα-helixtrans-58.4-35.1179.4-63-19.9000113R370 F374 E376R370-N372 PolarHBondContact O-N 3.49Å; R370-N372 VanDerWaalsContact O-N 3.09Å; N372-F374 VanDerWaalsContact C-N 3.32Å; N372-E376 WeakPolarHBondContact O-CB 3.48Å; N372-E376 PolarHBondContact O-N 3.08Å
373L94.2Very high93Very high21 Ų2175.7 Ų75.711%0.1135%0.345CS..Hα-helixtrans-66.8-37.1176.1-62178.6000111.2R370 R371 L377 L411 M415R370-L373 HydrophobicContact CB-CD1 4.33Å; R370-L373 WeakPolarHBondContact O-CB 3.12Å; R370-L373 PolarHBondContact O-N 2.94Å; R371-L373 VanDerWaalsContact C-N 3.25Å; R371-L373 PolarHBondContact O-N 2.98Å; L373-L377 WeakPolarHBondContact O-CG 3.31Å; L373-L377 PolarHBondContact O-N 3.31Å; L373-L411 HydrophobicContact CD2-CD2 4.08Å; L373-M415 HydrophobicContact CB-CB 4.48Å; L373-M415 HydrophobicContact CD1-CB 4.36Å
374F94.2Very high92.7Very high39 Ų3976.3 Ų76.317%0.17135%0.349CS..Hα-helixtrans-70.6-41.7177.3-174.8-95.9000112.1W367 R371 N372 E376 L377 K378 M415W367-F374 HydrophobicContact CH2-CB 4.16Å; W367-F374 AromaticContact CH2-CD1 3.5Å; W367-F374 HydrophobicContact CH2-CD1 3.5Å; W367-F374 AromaticContact CH2-CD2 3.71Å; W367-F374 HydrophobicContact CH2-CD2 3.71Å; W367-F374 AromaticContact CH2-CE1 3.75Å; W367-F374 HydrophobicContact CH2-CE1 3.75Å; W367-F374 AromaticContact CH2-CE2 3.95Å; W367-F374 HydrophobicContact CH2-CE2 3.95Å; W367-F374 AromaticContact CH2-CG 3.48Å; W367-F374 HydrophobicContact CH2-CG 3.48Å; W367-F374 VanDerWaalsContact CH2-CG 3.48Å; W367-F374 AromaticContact CH2-CZ 3.97Å; W367-F374 HydrophobicContact CH2-CZ 3.97Å; W367-F374 HydrophobicContact CZ2-CD1 4.04Å; W367-F374 HydrophobicContact CZ2-CE1 4.35Å; W367-F374 HydrophobicContact CZ2-CG 4.33Å; W367-F374 HydrophobicContact CZ3-CB 4.35Å; W367-F374 HydrophobicContact CZ3-CD1 4.4Å; W367-F374 AromaticContact CZ3-CD2 3.88Å; W367-F374 HydrophobicContact CZ3-CD2 3.88Å; W367-F374 HydrophobicContact CZ3-CE2 4.31Å; W367-F374 AromaticContact CZ3-CG 3.93Å; W367-F374 HydrophobicContact CZ3-CG 3.93Å; R371-F374 WeakPolarHBondContact O-CA 3.38Å; R371-F374 WeakPolarHBondContact O-CB 3.44Å; R371-F374 PolarHBondContact O-N 3.42Å; N372-F374 VanDerWaalsContact C-N 3.32Å; F374-E376 VanDerWaalsContact C-N 3.32Å; F374-E376 PolarHBondContact O-N 2.97Å; F374-L377 WeakPolarHBondContact O-CB 3.19Å; F374-L377 PolarHBondContact O-N 2.85Å; F374-K378 PolarHBondContact O-N 3.35Å; F374-M415 HydrophobicContact CB-SD 4.02Å; F374-M415 HydrophobicContact CD2-CE 4.34Å; F374-M415 HydrophobicContact CD2-SD 4.07Å
375E94.6Very high92.3Very high54 Ų5477.2 Ų77.225%0.25236%0.362SS..Hα-helixtrans-64-38174.8-60.8-65171.700111.3R371 K378 H379R371-E375 HydrophobicContact CG-CG 4.28Å; R371-E375 IonicContact CZ-OE1 3.77Å; R371-E375 IonicContact NE-OE1 2.63Å; R371-E375 PolarHBondContact NE-OE1 3.22Å; R371-E375 IonicContact NH2-OE1 3.14Å; R371-E375 PolarHBondContact O-N 3.12Å; E375-K378 WeakPolarHBondContact O-CB 3.5Å; E375-K378 PolarHBondContact O-N 3.37Å; E375-H379 PolarHBondContact O-N 3.18Å
376E94.7Very high92Very high64 Ų6474.5 Ų74.530%0.29935%0.349SS..Hα-helixtrans-63-43.4173.1-168.4-177.6161.700111.6N372 F374 K378 H379 L380 R407 L411N372-E376 WeakPolarHBondContact O-CB 3.48Å; N372-E376 PolarHBondContact O-N 3.08Å; F374-E376 VanDerWaalsContact C-N 3.32Å; F374-E376 PolarHBondContact O-N 2.97Å; E376-K378 VanDerWaalsContact C-N 3.31Å; E376-K378 PolarHBondContact O-N 3.48Å; E376-H379 PolarHBondContact O-N 3.31Å; E376-L380 HydrophobicContact CG-CD1 4.49Å; E376-L380 WeakPolarHBondContact O-CG 3.19Å; E376-L380 PolarHBondContact O-N 3.39Å; E376-R407 IonicContact OE1-CZ 3.3Å; E376-R407 VanDerWaalsContact OE1-CZ 3.3Å; E376-R407 IonicContact OE1-NE 3.01Å; E376-R407 PolarHBondContact OE1-NE 3.01Å; E376-R407 IonicContact OE1-NH2 2.73Å; E376-R407 PolarHBondContact OE1-NH2 2.88Å; E376-R407 IonicContact OE2-NH2 3.74Å; E376-L411 HydrophobicContact CB-CD1 4.16Å; E376-L411 HydrophobicContact CG-CD1 3.69Å; E376-L411 WeakPolarHBondContact OE1-CD1 3.3Å
377L93.3Very high91.5Very high1 Ų176.9 Ų76.91%0.00536%0.361CS..Hα-helixtrans-57.9-43.5173.4-79.7171.3000111.9L373 F374 L380 D381 I408 L411 M415L373-L377 WeakPolarHBondContact O-CG 3.31Å; L373-L377 PolarHBondContact O-N 3.31Å; F374-L377 WeakPolarHBondContact O-CB 3.19Å; F374-L377 PolarHBondContact O-N 2.85Å; L377-L380 PolarHBondContact O-N 3.48Å; L377-D381 PolarHBondContact O-N 3.1Å; L377-I408 HydrophobicContact CD2-CB 4.39Å; L377-I408 HydrophobicContact CD2-CG1 4.48Å; L377-I408 HydrophobicContact CD2-CG2 4.11Å; L377-L411 HydrophobicContact CD1-CB 4.47Å; L377-L411 HydrophobicContact CD2-CB 3.62Å; L377-L411 HydrophobicContact CD2-CD1 4.21Å; L377-L411 HydrophobicContact CG-CB 3.9Å; L377-L411 HydrophobicContact CG-CD1 4.36Å; L377-M415 HydrophobicContact CD1-CE 4.2Å; L377-M415 HydrophobicContact CD1-SD 4.12Å
378K91.9Very high91Very high125 Ų12577.8 Ų77.854%0.54337%0.365SS..Hα-helixtrans-64.3-41.1178-174.1-176.1175-169.70112.1F374 E375 E376 D381 F382F374-K378 PolarHBondContact O-N 3.35Å; E375-K378 WeakPolarHBondContact O-CB 3.5Å; E375-K378 PolarHBondContact O-N 3.37Å; E376-K378 VanDerWaalsContact C-N 3.31Å; E376-K378 PolarHBondContact O-N 3.48Å; K378-D381 PolarHBondContact O-N 3.01Å; K378-F382 PolarHBondContact O-N 2.94Å
379H92.7Very high90.5Very high126 Ų12679.2 Ų79.258%0.58337%0.366SS*.Hα-helixtrans-64.8-39.2175.8-69.3166.2000112.4E375 E376 F382 F383E375-H379 PolarHBondContact O-N 3.18Å; E376-H379 PolarHBondContact O-N 3.31Å; H379-F382 PolarHBondContact O-N 3.3Å; H379-F383 WeakPolarHBondContact O-CB 3.4Å; H379-F383 PolarHBondContact O-N 3.47Å
380L91.4Very high89.8Confident31 Ų3181.7 Ų81.716%0.16238%0.377CS..Hα-helixtrans-65.9-38.9176.2-69.7168.8000112.2E376 L377 F383 L384 I404 R407 I408 L411E376-L380 HydrophobicContact CG-CD1 4.49Å; E376-L380 WeakPolarHBondContact O-CG 3.19Å; E376-L380 PolarHBondContact O-N 3.39Å; L377-L380 PolarHBondContact O-N 3.48Å; L380-F383 PolarHBondContact O-N 3.15Å; L380-L384 WeakPolarHBondContact O-CB 3.49Å; L380-L384 PolarHBondContact O-N 3.12Å; L380-I404 HydrophobicContact CB-CG2 4.43Å; L380-I404 HydrophobicContact CD2-CG2 4.42Å; L380-R407 HydrophobicContact CD1-CB 4.18Å; L380-R407 HydrophobicContact CD1-CG 3.54Å; L380-R407 HydrophobicContact CD2-CG 4.43Å; L380-I408 HydrophobicContact CB-CD1 4.21Å; L380-I408 HydrophobicContact CB-CG1 3.92Å; L380-I408 HydrophobicContact CD1-CG1 4.06Å; L380-L411 HydrophobicContact CD1-CD1 3.5Å
381D87.7Confident89.2Confident76 Ų7679.3 Ų79.341%0.40637%0.373SS..Hα-helixtrans-65.6-42.7175.4-16957.9000111.8L377 K378 L384 A385L377-D381 PolarHBondContact O-N 3.1Å; K378-D381 PolarHBondContact O-N 3.01Å; D381-L384 WeakPolarHBondContact O-CB 3.34Å; D381-L384 PolarHBondContact O-N 3.4Å; D381-A385 PolarHBondContact O-N 2.59Å
382F89Confident88.8Confident119 Ų11979 Ų7952%0.52238%0.38SS..Hα-helixtrans-61.4-45.6172.8179.7-97.7000112.1K378 H379 L384 A385 E386K378-F382 PolarHBondContact O-N 2.94Å; H379-F382 PolarHBondContact O-N 3.3Å; F382-L384 VanDerWaalsContact C-N 3.29Å; F382-L384 PolarHBondContact O-N 2.99Å; F382-A385 WeakPolarHBondContact O-CB 3.36Å; F382-A385 PolarHBondContact O-N 2.69Å; F382-A385 VanDerWaalsContact O-N 3.1Å; F382-E386 HydrophobicContact CD1-CG 4.01Å; F382-E386 HydrophobicContact CE1-CG 3.65Å; F382-E386 VanDerWaalsContact CE1-OE1 3.24Å; F382-E386 WeakPolarHBondContact CE1-OE1 2.91Å; F382-E386 HydrophobicContact CZ-CG 4.05Å; F382-E386 WeakPolarHBondContact CZ-OE1 3.24Å; F382-E386 WeakPolarHBondContact O-CG 3.45Å; F382-E386 PolarHBondContact O-N 3.43Å
383F88.1Confident88.1Confident108 Ų10879.2 Ų79.247%0.47439%0.392SS..Hα-helixtrans-62.6-37.2177.6-174-108.8000112H379 L380 A385 E386 L387 I404H379-F383 WeakPolarHBondContact O-CB 3.4Å; H379-F383 PolarHBondContact O-N 3.47Å; L380-F383 PolarHBondContact O-N 3.15Å; F383-A385 VanDerWaalsContact C-N 3.34Å; F383-E386 WeakPolarHBondContact O-CB 3.43Å; F383-E386 PolarHBondContact O-N 3.24Å; F383-L387 HydrophobicContact CD1-CD1 4.31Å; F383-L387 HydrophobicContact CE1-CD1 4.03Å; F383-L387 HydrophobicContact CE1-CG 4.36Å; F383-L387 HydrophobicContact CZ-CD2 4.36Å; F383-L387 WeakPolarHBondContact O-CG 3.37Å; F383-L387 PolarHBondContact O-N 3.07Å; F383-I404 HydrophobicContact CD1-CD1 3.66Å; F383-I404 HydrophobicContact CD1-CG1 4.36Å; F383-I404 HydrophobicContact CE1-CD1 3.74Å; F383-I404 HydrophobicContact CE1-CG1 4.49Å
384L87.8Confident87.5Confident35 Ų3580.8 Ų80.818%0.18341%0.413CS..Hα-helixtrans-61-44.4172.2-173.264.8000111.1L380 D381 F382 E386 L387 Y388 I401L380-L384 WeakPolarHBondContact O-CB 3.49Å; L380-L384 PolarHBondContact O-N 3.12Å; D381-L384 WeakPolarHBondContact O-CB 3.34Å; D381-L384 PolarHBondContact O-N 3.4Å; F382-L384 VanDerWaalsContact C-N 3.29Å; F382-L384 PolarHBondContact O-N 2.99Å; L384-E386 PolarHBondContact O-N 3.19Å; L384-L387 PolarHBondContact O-N 3.32Å; L384-Y388 HydrophobicContact CD1-CE2 4.07Å; L384-Y388 WeakPolarHBondContact O-CD2 3.49Å; L384-I401 HydrophobicContact CD1-CB 3.79Å; L384-I401 HydrophobicContact CD1-CD1 4.07Å; L384-I401 HydrophobicContact CD1-CG2 3.41Å; L384-I401 VanDerWaalsContact CD1-CG2 3.41Å
385A86.9Confident86.9Confident57 Ų5781.3 Ų81.347%0.47142%0.422SS..Hα-helixtrans-64.8-36.7177.300000113.1D381 F382 F383 Y388 R389D381-A385 PolarHBondContact O-N 2.59Å; F382-A385 WeakPolarHBondContact O-CB 3.36Å; F382-A385 PolarHBondContact O-N 2.69Å; F382-A385 VanDerWaalsContact O-N 3.1Å; F383-A385 VanDerWaalsContact C-N 3.34Å; A385-Y388 PolarHBondContact O-N 2.92Å; A385-R389 PolarHBondContact O-N 2.79Å; A385-R389 VanDerWaalsContact O-N 3.12Å
386E86.9Confident86.1Confident55 Ų5586.6 Ų86.626%0.25745%0.45SS..Hα-helixtrans-59.9-44.1174.2-72.2-73.6165.900112.7F382 F383 L384 Y388 R389F382-E386 HydrophobicContact CD1-CG 4.01Å; F382-E386 HydrophobicContact CE1-CG 3.65Å; F382-E386 VanDerWaalsContact CE1-OE1 3.24Å; F382-E386 WeakPolarHBondContact CE1-OE1 2.91Å; F382-E386 HydrophobicContact CZ-CG 4.05Å; F382-E386 WeakPolarHBondContact CZ-OE1 3.24Å; F382-E386 WeakPolarHBondContact O-CG 3.45Å; F382-E386 PolarHBondContact O-N 3.43Å; F383-E386 WeakPolarHBondContact O-CB 3.43Å; F383-E386 PolarHBondContact O-N 3.24Å; L384-E386 PolarHBondContact O-N 3.19Å; E386-Y388 PolarHBondContact O-N 3.08Å; E386-R389 WeakPolarHBondContact O-CB 3.14Å; E386-R389 PolarHBondContact O-N 3.46Å; E386-R389 IonicContact OE1-CZ 3.46Å; E386-R389 IonicContact OE1-NH1 3.88Å; E386-R389 PolarHBondContact OE1-NH1 2.68Å; E386-R389 IonicContact OE1-NH2 2.71Å; E386-R389 PolarHBondContact OE1-NH2 3.01Å; E386-R389 IonicContact OE2-CZ 3.69Å; E386-R389 IonicContact OE2-NE 2.83Å; E386-R389 IonicContact OE2-NH1 2.9Å; E386-R389 PolarHBondContact OE2-NH1 3.09Å; E386-R389 IonicContact OE2-NH2 3.69Å
387L85.9Confident85.1Confident61 Ų6190.1 Ų90.132%0.31947%0.471SS..Hα-helixtrans-58.6-31.4179.2-70.8172.8000112.6F383 L384 P399 I401 I404F383-L387 HydrophobicContact CD1-CD1 4.31Å; F383-L387 HydrophobicContact CE1-CD1 4.03Å; F383-L387 HydrophobicContact CE1-CG 4.36Å; F383-L387 HydrophobicContact CZ-CD2 4.36Å; F383-L387 WeakPolarHBondContact O-CG 3.37Å; F383-L387 PolarHBondContact O-N 3.07Å; L384-L387 PolarHBondContact O-N 3.32Å; L387-P399 HydrophobicContact CB-CB 4.37Å; L387-P399 HydrophobicContact CB-CG 4.19Å; L387-I401 HydrophobicContact CD1-CG2 4.31Å; L387-I404 HydrophobicContact CD1-CD1 3.49Å; L387-I404 VanDerWaalsContact CD1-CD1 3.49Å
388Y83.2Confident84.3Confident86 Ų8694.8 Ų94.834%0.33750%0.503SS..Hα-helixtrans-94-8.9178.4-72.5-81.1000114.1L384 A385 E386 H390 L391 P399 I401L384-Y388 HydrophobicContact CD1-CE2 4.07Å; L384-Y388 WeakPolarHBondContact O-CD2 3.49Å; A385-Y388 PolarHBondContact O-N 2.92Å; E386-Y388 PolarHBondContact O-N 3.08Å; Y388-H390 VanDerWaalsContact C-N 3.32Å; Y388-H390 PolarHBondContact O-N 2.77Å; Y388-L391 HydrophobicContact CD1-CD1 3.7Å; Y388-L391 HydrophobicContact CE1-CD1 4.2Å; Y388-L391 HydrophobicContact CG-CD1 4.44Å; Y388-L391 PolarHBondContact O-N 3.08Å; Y388-L391 VanDerWaalsContact O-N 3.15Å; Y388-P399 HydrophobicContact CD1-CG 4.34Å; Y388-P399 HydrophobicContact CE1-CG 3.87Å; Y388-P399 HydrophobicContact CE2-CG 4.15Å; Y388-I401 HydrophobicContact CE2-CG2 4.07Å
389R82.3Confident83.9Confident132 Ų13290.5 Ų90.550%0.49849%0.487SS..Hα-helixtrans-58.3-39.9-169.6176.6176.5-68.5158.75.6114.2A385 E386A385-R389 PolarHBondContact O-N 2.79Å; A385-R389 VanDerWaalsContact O-N 3.12Å; E386-R389 WeakPolarHBondContact O-CB 3.14Å; E386-R389 PolarHBondContact O-N 3.46Å; E386-R389 IonicContact OE1-CZ 3.46Å; E386-R389 IonicContact OE1-NH1 3.88Å; E386-R389 PolarHBondContact OE1-NH1 2.68Å; E386-R389 IonicContact OE1-NH2 2.71Å; E386-R389 PolarHBondContact OE1-NH2 3.01Å; E386-R389 IonicContact OE2-CZ 3.69Å; E386-R389 IonicContact OE2-NE 2.83Å; E386-R389 IonicContact OE2-NH1 2.9Å; E386-R389 PolarHBondContact OE2-NH1 3.09Å; E386-R389 IonicContact OE2-NH2 3.69Å
390H79Confident83.6Confident162 Ų16290.1 Ų90.175%0.7549%0.49SS*.THydrogen-bonded Turntrans-97.74-175.4-61.2-61.6000113Y388Y388-H390 VanDerWaalsContact C-N 3.32Å; Y388-H390 PolarHBondContact O-N 2.77Å
391L81.9Confident83.5Confident65 Ų6589.9 Ų89.934%0.3449%0.488SS..  trans-86.3129.9174.9-56.6178.8000108.8Y388 S395 P399Y388-L391 HydrophobicContact CD1-CD1 3.7Å; Y388-L391 HydrophobicContact CE1-CD1 4.2Å; Y388-L391 HydrophobicContact CG-CD1 4.44Å; Y388-L391 PolarHBondContact O-N 3.08Å; Y388-L391 VanDerWaalsContact O-N 3.15Å; L391-S395 WeakPolarHBondContact CA-OG 3.33Å; L391-P399 HydrophobicContact CD1-CG 4.15Å
392D82.5Confident83.6Confident110 Ų11089.2 Ų89.259%0.58849%0.49SS*.  trans-109.2-179.5174.570.60.8000111G394 S395D392-G394 PolarHBondContact O-N 3.33Å; D392-G394 VanDerWaalsContact O-N 3.07Å; D392-G394 WeakPolarHBondContact OD1-CA 3.33Å; D392-G394 PolarHBondContact OD1-N 2.96Å; D392-S395 PolarHBondContact N-OG 3.12Å; D392-S395 VanDerWaalsContact O-CB 3.29Å; D392-S395 WeakPolarHBondContact O-CB 3.31Å; D392-S395 PolarHBondContact O-N 3.38Å; D392-S395 PolarHBondContact O-OG 3.43Å; D392-S395 PolarHBondContact OD1-N 3.11Å; D392-S395 PolarHBondContact OD1-OG 3.28Å
393S82.1Confident83.7Confident136 Ų13689.8 Ų89.895%0.95150%0.498SS*.THydrogen-bonded Turntrans-64.1-12178.755.70000114.3
394G80.4Confident83.8Confident55 Ų5585.7 Ų85.757%0.56748%0.481SS*.THydrogen-bonded Turntrans-95-6.3176.300000113.5D392 I396D392-G394 PolarHBondContact O-N 3.33Å; D392-G394 VanDerWaalsContact O-N 3.07Å; D392-G394 WeakPolarHBondContact OD1-CA 3.33Å; D392-G394 PolarHBondContact OD1-N 2.96Å; G394-I396 PolarHBondContact O-N 3.1Å
395S82.3Confident83.9Confident50 Ų5088.1 Ų88.135%0.3549%0.491SS..  trans-73.3124.8-177.1-610000111L391 D392L391-S395 WeakPolarHBondContact CA-OG 3.33Å; D392-S395 PolarHBondContact N-OG 3.12Å; D392-S395 VanDerWaalsContact O-CB 3.29Å; D392-S395 WeakPolarHBondContact O-CB 3.31Å; D392-S395 PolarHBondContact O-N 3.38Å; D392-S395 PolarHBondContact O-OG 3.43Å; D392-S395 PolarHBondContact OD1-N 3.11Å; D392-S395 PolarHBondContact OD1-OG 3.28Å
396I77.1Confident84.2Confident165 Ų16589.4 Ų89.485%0.84649%0.493SS*.  trans-95.1-25.6179.5-57.1169.6000110.7G394 C398G394-I396 PolarHBondContact O-N 3.1Å; I396-C398 PolarHBondContact O-N 3.42Å
397D75.1Confident84.5Confident138 Ų13891.7 Ų91.774%0.73850%0.5SS*.PPolyproline II helixtrans-78.2117-180-67.8-35.7000110.7
398C77Confident84.8Confident99 Ų9989.6 Ų89.667%0.66949%0.489SS*.PPolyproline II helixtrans-101.1120.1172.7-171.30000109I396I396-C398 PolarHBondContact O-N 3.42Å
399P82.7Confident85.3Confident34 Ų3491 Ų9122%0.22150%0.496CS..PPolyproline II helixtrans-63.4140.417823.7-31.1000110.7L387 Y388 L391 I401L387-P399 HydrophobicContact CB-CB 4.37Å; L387-P399 HydrophobicContact CB-CG 4.19Å; Y388-P399 HydrophobicContact CD1-CG 4.34Å; Y388-P399 HydrophobicContact CE1-CG 3.87Å; Y388-P399 HydrophobicContact CE2-CG 4.15Å; L391-P399 HydrophobicContact CD1-CG 4.15Å; P399-I401 PolarHBondContact O-N 2.94Å
400D85.5Confident85.8Confident118 Ų11888 Ų8863%0.63149%0.492SS*.  trans-75.2113.1173178.617.6000110.4S402D400-S402 WeakPolarHBondContact OD1-CB 3.3Å; D400-S402 PolarHBondContact OD1-N 3.06Å; D400-S402 PolarHBondContact OD1-OG 2.62Å
401I89.8Confident86.6Confident26 Ų2680.2 Ų80.213%0.13346%0.457CS..  trans-106.15.2-177.262.5173.3000112.8L384 L387 Y388 P399 N403 I404 Q405L384-I401 HydrophobicContact CD1-CB 3.79Å; L384-I401 HydrophobicContact CD1-CD1 4.07Å; L384-I401 HydrophobicContact CD1-CG2 3.41Å; L384-I401 VanDerWaalsContact CD1-CG2 3.41Å; L387-I401 HydrophobicContact CD1-CG2 4.31Å; Y388-I401 HydrophobicContact CE2-CG2 4.07Å; P399-I401 PolarHBondContact O-N 2.94Å; I401-N403 VanDerWaalsContact C-N 3.31Å; I401-N403 PolarHBondContact O-N 2.98Å; I401-I404 PolarHBondContact O-N 3.45Å; I401-I404 VanDerWaalsContact O-N 3.09Å; I401-Q405 HydrophobicContact CD1-CG 4.17Å; I401-Q405 HydrophobicContact CG1-CG 4.15Å; I401-Q405 WeakPolarHBondContact O-CG 3.41Å; I401-Q405 PolarHBondContact O-N 2.95Å
402S90.4Very high87.2Confident62 Ų6278.4 Ų78.443%0.43445%0.448SS..Hα-helixtrans-57.8-41.9-171.6-550000112.7D400 T406D400-S402 WeakPolarHBondContact OD1-CB 3.3Å; D400-S402 PolarHBondContact OD1-N 3.06Å; D400-S402 PolarHBondContact OD1-OG 2.62Å; S402-T406 WeakPolarHBondContact O-CB 3.43Å; S402-T406 PolarHBondContact O-N 3.35Å; S402-T406 PolarHBondContact O-OG1 3.42Å
403N90.8Very high87.8Confident132 Ų13278.6 Ų78.671%0.70645%0.445SS*.Hα-helixtrans-67.9-40.6178.2-72.6-31.5000112.3I401 T406 R407I401-N403 VanDerWaalsContact C-N 3.31Å; I401-N403 PolarHBondContact O-N 2.98Å; N403-T406 PolarHBondContact O-N 3.19Å; N403-R407 WeakPolarHBondContact O-CB 3.15Å; N403-R407 PolarHBondContact O-N 2.91Å
404I90.4Very high88.4Confident21 Ų2178 Ų7811%0.10842%0.422CS..Hα-helixtrans-66.1-48.2178.6-60.7165.9000109.5L380 F383 L387 I401 T406 R407 I408L380-I404 HydrophobicContact CB-CG2 4.43Å; L380-I404 HydrophobicContact CD2-CG2 4.42Å; F383-I404 HydrophobicContact CD1-CD1 3.66Å; F383-I404 HydrophobicContact CD1-CG1 4.36Å; F383-I404 HydrophobicContact CE1-CD1 3.74Å; F383-I404 HydrophobicContact CE1-CG1 4.49Å; L387-I404 HydrophobicContact CD1-CD1 3.49Å; L387-I404 VanDerWaalsContact CD1-CD1 3.49Å; I401-I404 PolarHBondContact O-N 3.45Å; I401-I404 VanDerWaalsContact O-N 3.09Å; I404-T406 VanDerWaalsContact C-N 3.32Å; I404-T406 PolarHBondContact O-N 2.81Å; I404-R407 PolarHBondContact O-N 3.32Å; I404-R407 VanDerWaalsContact O-N 3.16Å; I404-I408 HydrophobicContact CG2-CD1 3.93Å; I404-I408 HydrophobicContact CG2-CG1 4.47Å; I404-I408 WeakPolarHBondContact O-CG1 3.26Å; I404-I408 PolarHBondContact O-N 3.07Å
405Q89.8Confident89.1Confident87 Ų8775.4 Ų75.441%0.40740%0.395SS..Hα-helixtrans-59.4-43.2176.9-72.3-175.5-16.600111.9I401 R407 I408 K409I401-Q405 HydrophobicContact CD1-CG 4.17Å; I401-Q405 HydrophobicContact CG1-CG 4.15Å; I401-Q405 WeakPolarHBondContact O-CG 3.41Å; I401-Q405 PolarHBondContact O-N 2.95Å; Q405-R407 VanDerWaalsContact C-N 3.34Å; Q405-R407 PolarHBondContact O-N 3.39Å; Q405-I408 PolarHBondContact O-N 3.31Å; Q405-K409 WeakPolarHBondContact O-CG 3.19Å; Q405-K409 PolarHBondContact O-N 3.45Å
406T92.3Very high89.8Confident83 Ų8373.4 Ų73.451%0.50938%0.381SS..Hα-helixtrans-61.6-43.8176.1-59.80000111.1S402 N403 I404 K409 V410S402-T406 WeakPolarHBondContact O-CB 3.43Å; S402-T406 PolarHBondContact O-N 3.35Å; S402-T406 PolarHBondContact O-OG1 3.42Å; N403-T406 PolarHBondContact O-N 3.19Å; I404-T406 VanDerWaalsContact C-N 3.32Å; I404-T406 PolarHBondContact O-N 2.81Å; T406-K409 PolarHBondContact O-N 2.87Å; T406-V410 WeakPolarHBondContact O-CG2 3.47Å; T406-V410 PolarHBondContact O-N 3.44Å
407R93.6Very high90.7Very high104 Ų10469.3 Ų69.339%0.39236%0.359SS..Hα-helixtrans-62.7-43.8176.8-174.963.5176.7-171.3-0.8111.9E376 L380 N403 I404 Q405 K409 V410 L411E376-R407 IonicContact OE1-CZ 3.3Å; E376-R407 VanDerWaalsContact OE1-CZ 3.3Å; E376-R407 IonicContact OE1-NE 3.01Å; E376-R407 PolarHBondContact OE1-NE 3.01Å; E376-R407 IonicContact OE1-NH2 2.73Å; E376-R407 PolarHBondContact OE1-NH2 2.88Å; E376-R407 IonicContact OE2-NH2 3.74Å; L380-R407 HydrophobicContact CD1-CB 4.18Å; L380-R407 HydrophobicContact CD1-CG 3.54Å; L380-R407 HydrophobicContact CD2-CG 4.43Å; N403-R407 WeakPolarHBondContact O-CB 3.15Å; N403-R407 PolarHBondContact O-N 2.91Å; I404-R407 PolarHBondContact O-N 3.32Å; I404-R407 VanDerWaalsContact O-N 3.16Å; Q405-R407 VanDerWaalsContact C-N 3.34Å; Q405-R407 PolarHBondContact O-N 3.39Å; R407-K409 VanDerWaalsContact C-N 3.35Å; R407-K409 PolarHBondContact O-N 3.42Å; R407-V410 PolarHBondContact O-N 3.36Å; R407-L411 HydrophobicContact CG-CD1 4.03Å; R407-L411 HydrophobicContact CG-CG 4.43Å; R407-L411 WeakPolarHBondContact O-CB 3.36Å; R407-L411 WeakPolarHBondContact O-CG 3.3Å; R407-L411 PolarHBondContact O-N 3.06Å
408I93.4Very high91.7Very high17 Ų1764.5 Ų64.59%0.08734%0.336CS..Hα-helixtrans-58.3-46.2175.3-71.6170.7000110.6L377 L380 I404 Q405 V410 L411 T412 Y430L377-I408 HydrophobicContact CD2-CB 4.39Å; L377-I408 HydrophobicContact CD2-CG1 4.48Å; L377-I408 HydrophobicContact CD2-CG2 4.11Å; L380-I408 HydrophobicContact CB-CD1 4.21Å; L380-I408 HydrophobicContact CB-CG1 3.92Å; L380-I408 HydrophobicContact CD1-CG1 4.06Å; I404-I408 HydrophobicContact CG2-CD1 3.93Å; I404-I408 HydrophobicContact CG2-CG1 4.47Å; I404-I408 WeakPolarHBondContact O-CG1 3.26Å; I404-I408 PolarHBondContact O-N 3.07Å; Q405-I408 PolarHBondContact O-N 3.31Å; I408-V410 PolarHBondContact O-N 3.17Å; I408-L411 PolarHBondContact O-N 2.68Å; I408-T412 VanDerWaalsContact O-CB 3.22Å; I408-T412 WeakPolarHBondContact O-CB 3.4Å; I408-T412 PolarHBondContact O-N 3.02Å; I408-T412 PolarHBondContact O-OG1 2.99Å; I408-Y430 HydrophobicContact CG2-CE1 3.98Å
409K92.3Very high92.7Very high115 Ų11560.6 Ų60.650%0.531%0.307SS..Hα-helixtrans-60.5-45.4177.7-71.3-178.8-172.1-171.10111.8E117 Q405 T406 R407 T412 H413E117-K409 IonicContact OE2-NZ 3.33Å; E117-K409 PolarHBondContact OE2-NZ 3.43Å; Q405-K409 WeakPolarHBondContact O-CG 3.19Å; Q405-K409 PolarHBondContact O-N 3.45Å; T406-K409 PolarHBondContact O-N 2.87Å; R407-K409 VanDerWaalsContact C-N 3.35Å; R407-K409 PolarHBondContact O-N 3.42Å; K409-T412 PolarHBondContact O-N 2.87Å; K409-H413 WeakPolarHBondContact O-CB 3.49Å; K409-H413 PolarHBondContact O-N 3.4Å
410V94.2Very high93.3Very high68 Ų6859.6 Ų59.641%0.41230%0.303SS..Hα-helixtrans-64.2-45.8178.91710000111.8T406 R407 I408 H413 R414T406-V410 WeakPolarHBondContact O-CG2 3.47Å; T406-V410 PolarHBondContact O-N 3.44Å; R407-V410 PolarHBondContact O-N 3.36Å; I408-V410 PolarHBondContact O-N 3.17Å; V410-H413 PolarHBondContact O-N 2.81Å; V410-R414 WeakPolarHBondContact O-CB 3.23Å; V410-R414 VanDerWaalsContact O-CG 3.31Å; V410-R414 WeakPolarHBondContact O-CG 3.2Å; V410-R414 PolarHBondContact O-N 3.43Å
411L94.9Very high93.9Very high0 Ų056.7 Ų56.70%029%0.286CS..Hα-helixtrans-66.7-40.7178.7-71.3174000111.9L373 E376 L377 L380 R407 I408 R414 M415L373-L411 HydrophobicContact CD2-CD2 4.08Å; E376-L411 HydrophobicContact CB-CD1 4.16Å; E376-L411 HydrophobicContact CG-CD1 3.69Å; E376-L411 WeakPolarHBondContact OE1-CD1 3.3Å; L377-L411 HydrophobicContact CD1-CB 4.47Å; L377-L411 HydrophobicContact CD2-CB 3.62Å; L377-L411 HydrophobicContact CD2-CD1 4.21Å; L377-L411 HydrophobicContact CG-CB 3.9Å; L377-L411 HydrophobicContact CG-CD1 4.36Å; L380-L411 HydrophobicContact CD1-CD1 3.5Å; R407-L411 HydrophobicContact CG-CD1 4.03Å; R407-L411 HydrophobicContact CG-CG 4.43Å; R407-L411 WeakPolarHBondContact O-CB 3.36Å; R407-L411 WeakPolarHBondContact O-CG 3.3Å; R407-L411 PolarHBondContact O-N 3.06Å; I408-L411 PolarHBondContact O-N 2.68Å; L411-R414 PolarHBondContact O-N 3.03Å; L411-M415 WeakPolarHBondContact O-CB 3.35Å; L411-M415 PolarHBondContact O-N 2.87Å
412T95.2Very high94.2Very high26 Ų2655.5 Ų55.516%0.1628%0.28CS..Hα-helixtrans-56.6-51.6174.3-64.50000110.6I408 K409 R414 M415 D416I408-T412 VanDerWaalsContact O-CB 3.22Å; I408-T412 WeakPolarHBondContact O-CB 3.4Å; I408-T412 PolarHBondContact O-N 3.02Å; I408-T412 PolarHBondContact O-OG1 2.99Å; K409-T412 PolarHBondContact O-N 2.87Å; T412-R414 PolarHBondContact O-N 3.34Å; T412-M415 PolarHBondContact O-N 3.21Å; T412-D416 WeakPolarHBondContact O-CB 3.18Å; T412-D416 VanDerWaalsContact O-CG 3.31Å; T412-D416 PolarHBondContact O-N 2.85Å
413H94.6Very high94.5Very high114 Ų11452.6 Ų52.653%0.52826%0.259SS..Hα-helixtrans-59.6-46.2177.3178.9-86.7000112.3K409 V410 M415 D416 M417K409-H413 WeakPolarHBondContact O-CB 3.49Å; K409-H413 PolarHBondContact O-N 3.4Å; V410-H413 PolarHBondContact O-N 2.81Å; H413-M415 VanDerWaalsContact C-N 3.32Å; H413-M415 PolarHBondContact O-N 2.99Å; H413-D416 PolarHBondContact O-N 2.98Å; H413-M417 WeakPolarHBondContact O-CB 3.27Å; H413-M417 VanDerWaalsContact O-CG 3.27Å; H413-M417 WeakPolarHBondContact O-CG 3.3Å; H413-M417 PolarHBondContact O-N 3.46Å
414R95.3Very high94.9Very high123 Ų12346.3 Ų46.346%0.46423%0.226SC..Hα-helixtrans-61.5-40.5178.7-74.9175.966.5-163.5-0.3112.5V410 L411 T412 S418V410-R414 WeakPolarHBondContact O-CB 3.23Å; V410-R414 VanDerWaalsContact O-CG 3.31Å; V410-R414 WeakPolarHBondContact O-CG 3.2Å; V410-R414 PolarHBondContact O-N 3.43Å; L411-R414 PolarHBondContact O-N 3.03Å; T412-R414 PolarHBondContact O-N 3.34Å; R414-S418 PolarHBondContact O-OG 3.01Å; R414-S418 VanDerWaalsContact O-OG 3.1Å
415M95.5Very high95.3Very high1 Ų145.5 Ų45.51%0.00522%0.222CC..Hα-helixtrans-68-48.3177.9-171.3179.378.200110.5L373 F374 L377 L411 T412 H413 M417 S418 Y419 R427 G429L373-M415 HydrophobicContact CB-CB 4.48Å; L373-M415 HydrophobicContact CD1-CB 4.36Å; F374-M415 HydrophobicContact CB-SD 4.02Å; F374-M415 HydrophobicContact CD2-CE 4.34Å; F374-M415 HydrophobicContact CD2-SD 4.07Å; L377-M415 HydrophobicContact CD1-CE 4.2Å; L377-M415 HydrophobicContact CD1-SD 4.12Å; L411-M415 WeakPolarHBondContact O-CB 3.35Å; L411-M415 PolarHBondContact O-N 2.87Å; T412-M415 PolarHBondContact O-N 3.21Å; H413-M415 VanDerWaalsContact C-N 3.32Å; H413-M415 PolarHBondContact O-N 2.99Å; M415-M417 PolarHBondContact O-N 2.99Å; M415-S418 VanDerWaalsContact O-CB 3.27Å; M415-S418 WeakPolarHBondContact O-CB 3.34Å; M415-S418 PolarHBondContact O-N 2.77Å; M415-S418 VanDerWaalsContact O-N 3.07Å; M415-Y419 HydrophobicContact CG-CE2 4.34Å; M415-Y419 VanDerWaalsContact O-CD2 3.31Å; M415-Y419 WeakPolarHBondContact O-CD2 3.5Å; M415-R427 HydrophobicContact CE-CG 4.49Å; M415-G429 VanDerWaalsContact CE-O 3.26Å; M415-G429 WeakPolarHBondContact CE-O 3.44Å
416D96.4Very high95.6Very high9 Ų942.8 Ų42.85%0.04821%0.21CC..Hα-helixtrans-60.4-45.6-178.7-73.95.5000111.3T412 H413 S418 Y419 G423 S428 G429T412-D416 WeakPolarHBondContact O-CB 3.18Å; T412-D416 VanDerWaalsContact O-CG 3.31Å; T412-D416 PolarHBondContact O-N 2.85Å; H413-D416 PolarHBondContact O-N 2.98Å; D416-S418 PolarHBondContact O-N 3.4Å; D416-Y419 PolarHBondContact O-N 2.69Å; D416-G423 WeakPolarHBondContact O-CA 3.31Å; D416-S428 WeakPolarHBondContact OD1-CA 3.4Å; D416-S428 WeakPolarHBondContact OD2-CA 3.36Å; D416-S428 VanDerWaalsContact OD2-CB 3.29Å; D416-S428 WeakPolarHBondContact OD2-CB 3.4Å; D416-S428 PolarHBondContact OD2-OG 2.89Å; D416-G429 PolarHBondContact OD1-N 2.96Å; D416-G429 VanDerWaalsContact OD1-N 3.08Å
417M96.1Very high95.9Very high79 Ų7941 Ų4139%0.38919%0.194SC..THydrogen-bonded Turntrans-60.2-18.4177.4-70.3-58.197.200114.4H413 M415 Y419 Q421H413-M417 WeakPolarHBondContact O-CB 3.27Å; H413-M417 VanDerWaalsContact O-CG 3.27Å; H413-M417 WeakPolarHBondContact O-CG 3.3Å; H413-M417 PolarHBondContact O-N 3.46Å; M415-M417 PolarHBondContact O-N 2.99Å; M417-Y419 PolarHBondContact O-N 3.43Å; M417-Q421 WeakPolarHBondContact CE-O 3.39Å
418S96.3Very high96Very high36 Ų3636.7 Ų36.725%0.25218%0.18SC..THydrogen-bonded Turntrans-70.9-20.2176.4-58.20000112.9R414 M415 D416R414-S418 PolarHBondContact O-OG 3.01Å; R414-S418 VanDerWaalsContact O-OG 3.1Å; M415-S418 VanDerWaalsContact O-CB 3.27Å; M415-S418 WeakPolarHBondContact O-CB 3.34Å; M415-S418 PolarHBondContact O-N 2.77Å; M415-S418 VanDerWaalsContact O-N 3.07Å; D416-S418 PolarHBondContact O-N 3.4Å
419Y96.6Very high96.1Very high17 Ų1735.9 Ų35.97%0.06718%0.176CC..THydrogen-bonded Turntrans-93.5-36.2178.7-64.4-94.5000112.1K362 E363 V366 M415 D416 M417K362-Y419 PolarHBondContact NZ-O 3.29Å; E363-Y419 HydrophobicContact CB-CE1 4.45Å; E363-Y419 WeakPolarHBondContact OE2-CD1 3.18Å; E363-Y419 WeakPolarHBondContact OE2-CE1 3.35Å; V366-Y419 HydrophobicContact CB-CD1 4.03Å; V366-Y419 HydrophobicContact CB-CE1 3.73Å; V366-Y419 HydrophobicContact CG1-CD1 3.89Å; V366-Y419 HydrophobicContact CG1-CD2 3.95Å; V366-Y419 HydrophobicContact CG1-CE1 3.67Å; V366-Y419 HydrophobicContact CG1-CE2 3.72Å; V366-Y419 HydrophobicContact CG1-CG 4.02Å; M415-Y419 HydrophobicContact CG-CE2 4.34Å; M415-Y419 VanDerWaalsContact O-CD2 3.31Å; M415-Y419 WeakPolarHBondContact O-CD2 3.5Å; D416-Y419 PolarHBondContact O-N 2.69Å; M417-Y419 PolarHBondContact O-N 3.43Å
420G96.2Very high96Very high13 Ų1336.1 Ų36.113%0.13417%0.174CC..  trans157.7178.2-17500000110.5S81 M422 G423S81-G420 CarbonylContact O-C 3.55Å; S81-G420 WeakPolarHBondContact O-CA 3.41Å; G420-M422 VanDerWaalsContact C-N 3.32Å; G420-M422 PolarHBondContact O-N 3.4Å; G420-G423 WeakPolarHBondContact O-CA 3.29Å; G420-G423 PolarHBondContact O-N 3.42Å
421Q97.1Very high96Very high57 Ų5734.9 Ų34.927%0.26617%0.167SC..THydrogen-bonded Turntrans-66.4-33.6-176.4-53.3-178.840.800112.2D79 S81 F82 F114 M417 G423D79-Q421 PolarHBondContact OD2-NE2 2.86Å; S81-Q421 PolarHBondContact O-N 2.89Å; S81-Q421 PolarHBondContact OG-NE2 3.47Å; F82-Q421 HydrophobicContact CD2-CB 4.23Å; F114-Q421 VanDerWaalsContact CE1-O 3.3Å; F114-Q421 WeakPolarHBondContact CE1-O 3.38Å; F114-Q421 HydrophobicContact CE2-CB 4.07Å; F114-Q421 HydrophobicContact CZ-CB 3.73Å; F114-Q421 VanDerWaalsContact CZ-O 3.27Å; F114-Q421 WeakPolarHBondContact CZ-O 3.43Å; M417-Q421 WeakPolarHBondContact CE-O 3.39Å; Q421-G423 VanDerWaalsContact C-N 3.32Å
422M97.3Very high96.1Very high1 Ų139 Ų391%0.00519%0.186CC..THydrogen-bonded Turntrans-87.73.9171.9-74.1-67.9-142.800113.7F82 T84 I87 L96 K98 V107 F114 G420F82-M422 HydrophobicContact CE1-CE 4.46Å; F82-M422 HydrophobicContact CZ-CE 4.2Å; F82-M422 WeakPolarHBondContact O-CB 3.25Å; F82-M422 WeakPolarHBondContact O-CG 3.4Å; F82-M422 PolarHBondContact O-N 3.44Å; T84-M422 WeakPolarHBondContact OG1-CB 3.33Å; I87-M422 HydrophobicContact CD1-CB 4.36Å; I87-M422 HydrophobicContact CD1-CE 3.99Å; I87-M422 HydrophobicContact CD1-CG 4.34Å; I87-M422 HydrophobicContact CD1-SD 4.07Å; I87-M422 HydrophobicContact CG1-CE 4.38Å; I87-M422 HydrophobicContact CG2-CE 4.25Å; L96-M422 HydrophobicContact CB-CE 3.51Å; L96-M422 HydrophobicContact CD1-CE 4.05Å; L96-M422 HydrophobicContact CG-CE 4.45Å; K98-M422 WeakPolarHBondContact CD-O 3.4Å; K98-M422 PolarHBondContact NZ-O 2.92Å; V107-M422 HydrophobicContact CG1-SD 4.1Å; F114-M422 HydrophobicContact CE1-SD 3.84Å; F114-M422 HydrophobicContact CZ-SD 4.33Å; G420-M422 VanDerWaalsContact C-N 3.32Å; G420-M422 PolarHBondContact O-N 3.4Å
423G97.3Very high96.3Very high1 Ų138 Ų381%0.0118%0.18CC..  trans69-168178.800000115.2T84 D416 G420 Q421T84-G423 WeakPolarHBondContact CG2-O 3.12Å; T84-G423 PolarHBondContact OG1-O 2.92Å; D416-G423 WeakPolarHBondContact O-CA 3.31Å; G420-G423 WeakPolarHBondContact O-CA 3.29Å; G420-G423 PolarHBondContact O-N 3.42Å; Q421-G423 VanDerWaalsContact C-N 3.32Å
424S98.1Very high96.4Very high1 Ų132.9 Ų32.91%0.00716%0.157CC..  trans-61.7142.7-177.7166.60000112.7K98 E363 L426 R427K98-S424 WeakPolarHBondContact CE-O 3.26Å; K98-S424 PolarHBondContact NZ-O 3.49Å; E363-S424 WeakPolarHBondContact OE1-CA 3.38Å; E363-S424 PolarHBondContact OE1-OG 3.04Å; E363-S424 WeakPolarHBondContact OE2-CB 3.22Å; E363-S424 PolarHBondContact OE2-OG 3.26Å; S424-L426 PolarHBondContact O-N 3.3Å; S424-L426 PolarHBondContact OG-N 2.96Å; S424-R427 PolarHBondContact OG-N 2.9Å
425L97.9Very high96.5Very high3 Ų327.2 Ų27.22%0.01614%0.135CC..SBendtrans-54.5-33.1169.6175.858.5000112.1T84 R85 V357 E359 E363 T433 F435T84-L425 HydrophobicContact CG2-CB 4.15Å; T84-L425 HydrophobicContact CG2-CD1 4.45Å; R85-L425 HydrophobicContact CB-CD1 3.99Å; R85-L425 WeakPolarHBondContact O-CD1 3.38Å; V357-L425 HydrophobicContact CG1-CD2 3.72Å; E359-L425 HydrophobicContact CB-CD2 4.45Å; E363-L425 WeakPolarHBondContact OE1-CB 3.27Å; E363-L425 PolarHBondContact OE1-N 3.47Å; L425-T433 WeakPolarHBondContact O-CG2 3.36Å; L425-T433 PolarHBondContact O-OG1 3.46Å; L425-F435 HydrophobicContact CD1-CB 4.14Å; L425-F435 HydrophobicContact CD1-CD1 3.64Å; L425-F435 HydrophobicContact CD1-CD2 4.09Å; L425-F435 HydrophobicContact CD1-CE1 4.04Å; L425-F435 HydrophobicContact CD1-CE2 4.44Å; L425-F435 HydrophobicContact CD1-CG 3.67Å; L425-F435 HydrophobicContact CD1-CZ 4.42Å; L425-F435 HydrophobicContact CD2-CD1 3.96Å; L425-F435 HydrophobicContact CD2-CE1 3.6Å; L425-F435 HydrophobicContact CD2-CZ 4.1Å; L425-F435 HydrophobicContact CG-CD1 3.61Å; L425-F435 HydrophobicContact CG-CE1 3.83Å; L425-F435 HydrophobicContact CG-CG 4.18Å
426L98Very high96.6Very high31 Ų3127.5 Ų27.516%0.16214%0.137CC..SBendtrans-97.7-21.6-167.2-57.2178.9000113.9L360 S424 Q432 T433 F435 A436 L439L360-L426 HydrophobicContact CD1-CD1 4.33Å; S424-L426 PolarHBondContact O-N 3.3Å; S424-L426 PolarHBondContact OG-N 2.96Å; L426-Q432 WeakPolarHBondContact O-CA 3.42Å; L426-T433 PolarHBondContact O-N 3.32Å; L426-T433 PolarHBondContact O-OG1 3.4Å; L426-F435 HydrophobicContact CD2-CD1 4.15Å; L426-F435 HydrophobicContact CD2-CE1 4.43Å; L426-A436 HydrophobicContact CB-CB 4.24Å; L426-A436 HydrophobicContact CD2-CB 4.19Å; L426-A436 WeakPolarHBondContact O-CB 3.44Å; L426-L439 HydrophobicContact CD2-CD1 4.33Å
427R97.6Very high96.7Very high46 Ų4628.7 Ų28.717%0.17415%0.147CC..EExtended strand (participates in β ladder)trans-158.1166.4-174.663-172.870.9-132.54.4114.6K98 M415 S424 G429 T431K98-R427 PolarHBondContact NZ-O 3.43Å; M415-R427 HydrophobicContact CE-CG 4.49Å; S424-R427 PolarHBondContact OG-N 2.9Å; R427-G429 WeakPolarHBondContact CD-O 3.36Å; R427-T431 CarbonylContact C-O 3.55Å; R427-T431 WeakPolarHBondContact CA-O 3.27Å; R427-T431 VanDerWaalsContact CB-O 3.29Å; R427-T431 WeakPolarHBondContact CB-O 3.4Å
428S96.8Very high96.7Very high13 Ų1325.8 Ų25.89%0.09113%0.132CC..EExtended strand (participates in β ladder)trans-129115.7157.2177.50000107.4D416 Y430 T431D416-S428 WeakPolarHBondContact OD1-CA 3.4Å; D416-S428 WeakPolarHBondContact OD2-CA 3.36Å; D416-S428 VanDerWaalsContact OD2-CB 3.29Å; D416-S428 WeakPolarHBondContact OD2-CB 3.4Å; D416-S428 PolarHBondContact OD2-OG 2.89Å; S428-Y430 PolarHBondContact O-N 3Å; S428-T431 PolarHBondContact N-O 3.09Å; S428-T431 PolarHBondContact O-N 3.03Å
429G94Very high96.7Very high0 Ų024.4 Ų24.40%012%0.122CC..THydrogen-bonded Turntrans57.3-130.1-170.500000111.7M415 D416 R427 T431M415-G429 VanDerWaalsContact CE-O 3.26Å; M415-G429 WeakPolarHBondContact CE-O 3.44Å; D416-G429 PolarHBondContact OD1-N 2.96Å; D416-G429 VanDerWaalsContact OD1-N 3.08Å; R427-G429 WeakPolarHBondContact CD-O 3.36Å; G429-T431 VanDerWaalsContact C-N 3.34Å
430Y90.1Very high96.7Very high120 Ų12027 Ų2747%0.47114%0.136SC..THydrogen-bonded Turntrans-81.2-10.9175.260.4-96.3000113.9I408 S428I408-Y430 HydrophobicContact CG2-CE1 3.98Å; S428-Y430 PolarHBondContact O-N 3Å
431T95.1Very high96.7Very high41 Ų4134 Ų3425%0.25216%0.159SC..EExtended strand (participates in β ladder)trans-90.5128-173.5-54.60000111.3D100 L106 R427 S428 G429D100-T431 HydrophobicContact CB-CG2 4.08Å; L106-T431 HydrophobicContact CD1-CG2 4.29Å; L106-T431 HydrophobicContact CD2-CG2 3.63Å; R427-T431 CarbonylContact C-O 3.55Å; R427-T431 WeakPolarHBondContact CA-O 3.27Å; R427-T431 VanDerWaalsContact CB-O 3.29Å; R427-T431 WeakPolarHBondContact CB-O 3.4Å; S428-T431 PolarHBondContact N-O 3.09Å; S428-T431 PolarHBondContact O-N 3.03Å; G429-T431 VanDerWaalsContact C-N 3.34Å
432Q97.8Very high96.7Very high86 Ų8632.4 Ų32.440%0.40215%0.15SC..EExtended strand (participates in β ladder)trans-74.9145.4178.2-69-177.8-26.800111.9D100 L426 A436D100-Q432 WeakPolarHBondContact CB-O 3.46Å; L426-Q432 WeakPolarHBondContact O-CA 3.42Å; Q432-A436 HydrophobicContact CB-CB 4.21Å
433T98.3Very high96.8Very high6 Ų632.3 Ų32.34%0.03715%0.15CC..PPolyproline II helixtrans-75.5163.9173.559.40000111.9K98 V99 L106 L425 L426 F435 A436 S437K98-T433 HydrophobicContact CD-CG2 4.29Å; K98-T433 HydrophobicContact CG-CG2 4.1Å; V99-T433 CarbonylContact O-C 3.46Å; V99-T433 WeakPolarHBondContact O-CA 3.44Å; L106-T433 HydrophobicContact CD1-CG2 4.35Å; L425-T433 WeakPolarHBondContact O-CG2 3.36Å; L425-T433 PolarHBondContact O-OG1 3.46Å; L426-T433 PolarHBondContact O-N 3.32Å; L426-T433 PolarHBondContact O-OG1 3.4Å; T433-F435 PolarHBondContact O-N 3.27Å; T433-A436 PolarHBondContact O-N 3.34Å; T433-A436 PolarHBondContact OG1-N 3.26Å; T433-A436 VanDerWaalsContact OG1-N 3.12Å; T433-S437 PolarHBondContact O-N 3.01Å
434L96.9Very high96.8Very high7 Ų732.3 Ų32.34%0.03715%0.15CC..Hα-helixtrans-52.5-43.1166.8177.461.2000111.4V99 M139 S437 Q438V99-L434 HydrophobicContact CG2-CB 4.16Å; V99-L434 HydrophobicContact CG2-CD2 4.22Å; V99-L434 PolarHBondContact O-N 3.04Å; M139-L434 HydrophobicContact CE-CD2 4.23Å; M139-L434 HydrophobicContact SD-CD2 3.95Å; L434-S437 PolarHBondContact O-N 3.42Å; L434-Q438 HydrophobicContact CD1-CG 4.23Å; L434-Q438 HydrophobicContact CG-CG 4.49Å; L434-Q438 WeakPolarHBondContact O-CG 3.34Å; L434-Q438 PolarHBondContact O-N 3.48Å
435F97.6Very high96.9Very high4 Ų432.3 Ų32.32%0.01815%0.149CC..Hα-helixtrans-60.2-47.8178.6-173.7-86000111.6I338 L355 V357 L425 L426 T433 S437 Q438 L439I338-F435 HydrophobicContact CB-CE2 3.97Å; I338-F435 HydrophobicContact CG2-CD2 4.08Å; I338-F435 HydrophobicContact CG2-CE2 3.77Å; L355-F435 HydrophobicContact CD2-CZ 4.38Å; V357-F435 HydrophobicContact CG1-CE1 4.5Å; L425-F435 HydrophobicContact CD1-CB 4.14Å; L425-F435 HydrophobicContact CD1-CD1 3.64Å; L425-F435 HydrophobicContact CD1-CD2 4.09Å; L425-F435 HydrophobicContact CD1-CE1 4.04Å; L425-F435 HydrophobicContact CD1-CE2 4.44Å; L425-F435 HydrophobicContact CD1-CG 3.67Å; L425-F435 HydrophobicContact CD1-CZ 4.42Å; L425-F435 HydrophobicContact CD2-CD1 3.96Å; L425-F435 HydrophobicContact CD2-CE1 3.6Å; L425-F435 HydrophobicContact CD2-CZ 4.1Å; L425-F435 HydrophobicContact CG-CD1 3.61Å; L425-F435 HydrophobicContact CG-CE1 3.83Å; L425-F435 HydrophobicContact CG-CG 4.18Å; L426-F435 HydrophobicContact CD2-CD1 4.15Å; L426-F435 HydrophobicContact CD2-CE1 4.43Å; T433-F435 PolarHBondContact O-N 3.27Å; F435-S437 VanDerWaalsContact C-N 3.34Å; F435-S437 PolarHBondContact O-N 2.94Å; F435-Q438 PolarHBondContact O-N 3.01Å; F435-L439 HydrophobicContact CE1-CD1 4.02Å; F435-L439 WeakPolarHBondContact O-CB 3.42Å; F435-L439 PolarHBondContact O-N 2.91Å
436A97.9Very high96.9Very high6 Ų634.2 Ų34.25%0.0516%0.157CC..Hα-helixtrans-59.7-43.5176.700000112.3L426 Q432 T433 Q438 L439 I440L426-A436 HydrophobicContact CB-CB 4.24Å; L426-A436 HydrophobicContact CD2-CB 4.19Å; L426-A436 WeakPolarHBondContact O-CB 3.44Å; Q432-A436 HydrophobicContact CB-CB 4.21Å; T433-A436 PolarHBondContact O-N 3.34Å; T433-A436 PolarHBondContact OG1-N 3.26Å; T433-A436 VanDerWaalsContact OG1-N 3.12Å; A436-Q438 PolarHBondContact O-N 2.93Å; A436-L439 PolarHBondContact O-N 3.36Å; A436-I440 VanDerWaalsContact O-CG1 3.32Å; A436-I440 WeakPolarHBondContact O-CG1 3.41Å; A436-I440 PolarHBondContact O-N 3.41Å
437S97.2Very high96.9Very high35 Ų3532.8 Ų32.825%0.24515%0.149CC..Hα-helixtrans-62.8-41.5177.1-1760000112.2S101 T433 L434 F435 R441S101-S437 WeakPolarHBondContact CB-OG 3.49Å; T433-S437 PolarHBondContact O-N 3.01Å; L434-S437 PolarHBondContact O-N 3.42Å; F435-S437 VanDerWaalsContact C-N 3.34Å; F435-S437 PolarHBondContact O-N 2.94Å; S437-R441 WeakPolarHBondContact O-CB 3.38Å; S437-R441 PolarHBondContact O-N 3.29Å
438Q96.4Very high96.8Very high17 Ų1731.1 Ų31.18%0.07914%0.144CC..Hα-helixtrans-65.5-42.6175.5-71.7-179.4-11.600112I338 L434 F435 A436 R441 Y442I338-Q438 HydrophobicContact CD1-CB 4.24Å; I338-Q438 HydrophobicContact CG1-CB 3.83Å; L434-Q438 HydrophobicContact CD1-CG 4.23Å; L434-Q438 HydrophobicContact CG-CG 4.49Å; L434-Q438 WeakPolarHBondContact O-CG 3.34Å; L434-Q438 PolarHBondContact O-N 3.48Å; F435-Q438 PolarHBondContact O-N 3.01Å; A436-Q438 PolarHBondContact O-N 2.93Å; Q438-R441 PolarHBondContact O-N 2.98Å; Q438-Y442 HydrophobicContact CB-CD2 4.08Å; Q438-Y442 HydrophobicContact CB-CE2 4.34Å; Q438-Y442 HydrophobicContact CG-CD2 4.43Å; Q438-Y442 HydrophobicContact CG-CE2 4.2Å; Q438-Y442 WeakPolarHBondContact O-CB 3.36Å; Q438-Y442 VanDerWaalsContact O-CD2 3.23Å; Q438-Y442 WeakPolarHBondContact O-CD2 3.44Å; Q438-Y442 PolarHBondContact O-N 3.42Å
439L97.6Very high96.9Very high7 Ų732.1 Ų32.14%0.03715%0.15CC..Hα-helixtrans-56.6-54.1175.2-178.7161.1000110.3N25 I338 L355 V357 L426 F435 A436 R441 Y442 A443 Y446N25-L439 PolarHBondContact ND2-O 3.18Å; I338-L439 HydrophobicContact CD1-CB 4.47Å; L355-L439 HydrophobicContact CD2-CB 4.2Å; L355-L439 HydrophobicContact CD2-CD1 3.74Å; L355-L439 HydrophobicContact CD2-CG 3.72Å; V357-L439 HydrophobicContact CG2-CD1 3.97Å; L426-L439 HydrophobicContact CD2-CD1 4.33Å; F435-L439 HydrophobicContact CE1-CD1 4.02Å; F435-L439 WeakPolarHBondContact O-CB 3.42Å; F435-L439 PolarHBondContact O-N 2.91Å; A436-L439 PolarHBondContact O-N 3.36Å; L439-R441 VanDerWaalsContact C-N 3.27Å; L439-R441 PolarHBondContact O-N 3.18Å; L439-Y442 PolarHBondContact O-N 2.72Å; L439-A443 VanDerWaalsContact O-CB 3.32Å; L439-A443 WeakPolarHBondContact O-CB 3.41Å; L439-A443 PolarHBondContact O-N 3Å; L439-Y446 HydrophobicContact CD1-CD2 4.18Å; L439-Y446 HydrophobicContact CD1-CG 4.37Å; L439-Y446 HydrophobicContact CD2-CD1 3.68Å; L439-Y446 HydrophobicContact CD2-CD2 4.23Å; L439-Y446 HydrophobicContact CD2-CE1 3.78Å; L439-Y446 HydrophobicContact CD2-CE2 4.35Å; L439-Y446 HydrophobicContact CD2-CG 3.91Å; L439-Y446 HydrophobicContact CG-CG 4.39Å
440I96.8Very high97Very high72 Ų7232.2 Ų32.237%0.36915%0.151SC..Hα-helixtrans-58.8-42.1178.9-67.3166.3000110.5R26 A436R26-I440 VanDerWaalsContact CZ-O 3.26Å; R26-I440 PolarHBondContact NH1-O 2.88Å; R26-I440 PolarHBondContact NH2-O 2.81Å; A436-I440 VanDerWaalsContact O-CG1 3.32Å; A436-I440 WeakPolarHBondContact O-CG1 3.41Å; A436-I440 PolarHBondContact O-N 3.41Å
441R96.2Very high97.3Very high160 Ų16026.9 Ų26.960%0.60413%0.13SC*.Hα-helixtrans-76-34.3-174-169.8171.9-170.9174.75.2114.4R26 S437 Q438 L439R26-R441 VanDerWaalsContact CZ-O 3.24Å; R26-R441 PolarHBondContact NH1-O 3.21Å; R26-R441 VanDerWaalsContact NH1-O 3.08Å; R26-R441 PolarHBondContact NH2-O 3Å; S437-R441 WeakPolarHBondContact O-CB 3.38Å; S437-R441 PolarHBondContact O-N 3.29Å; Q438-R441 PolarHBondContact O-N 2.98Å; L439-R441 VanDerWaalsContact C-N 3.27Å; L439-R441 PolarHBondContact O-N 3.18Å
442Y97.1Very high97.4Very high23 Ų2325.2 Ų25.29%0.0912%0.12CC..Hα-helixtrans-114.8-33.7-169.1-57.3-59.5000114.4R26 L343 K347 T353 Q438 L439 D444R26-Y442 VanDerWaalsContact NH2-C 3.3Å; L343-Y442 HydrophobicContact CB-CD2 4.12Å; L343-Y442 HydrophobicContact CB-CG 4.19Å; L343-Y442 HydrophobicContact CD1-CD2 3.73Å; L343-Y442 HydrophobicContact CD1-CE1 4.49Å; L343-Y442 HydrophobicContact CD1-CE2 3.35Å; L343-Y442 HydrophobicContact CD1-CG 4.43Å; L343-Y442 HydrophobicContact CG-CD1 4.25Å; L343-Y442 HydrophobicContact CG-CD2 3.9Å; L343-Y442 HydrophobicContact CG-CE1 4.21Å; L343-Y442 HydrophobicContact CG-CE2 3.85Å; L343-Y442 HydrophobicContact CG-CG 4.1Å; K347-Y442 HydrophobicContact CD-CE1 4.35Å; K347-Y442 VanDerWaalsContact CE-OH 3.23Å; K347-Y442 WeakPolarHBondContact CE-OH 3.33Å; K347-Y442 HydrophobicContact CG-CE1 4.29Å; K347-Y442 PolarHBondContact NZ-OH 3.11Å; K347-Y442 VanDerWaalsContact NZ-OH 3.1Å; T353-Y442 PolarHBondContact OG1-O 3.15Å; Q438-Y442 HydrophobicContact CB-CD2 4.08Å; Q438-Y442 HydrophobicContact CB-CE2 4.34Å; Q438-Y442 HydrophobicContact CG-CD2 4.43Å; Q438-Y442 HydrophobicContact CG-CE2 4.2Å; Q438-Y442 WeakPolarHBondContact O-CB 3.36Å; Q438-Y442 VanDerWaalsContact O-CD2 3.23Å; Q438-Y442 WeakPolarHBondContact O-CD2 3.44Å; Q438-Y442 PolarHBondContact O-N 3.42Å; L439-Y442 PolarHBondContact O-N 2.72Å; Y442-D444 PolarHBondContact O-N 3Å
443A98.1Very high97.4Very high0 Ų021.3 Ų21.30%010%0.102CC..  trans-83.1111.7178.800000110.6N25 R26 I342 T353 L355 L439N25-A443 WeakPolarHBondContact CB-O 3.42Å; N25-A443 PolarHBondContact ND2-O 3.33Å; R26-A443 PolarHBondContact NH2-O 2.82Å; I342-A443 HydrophobicContact CG2-CB 4.03Å; T353-A443 WeakPolarHBondContact OG1-CA 3.36Å; L355-A443 HydrophobicContact CB-CB 3.63Å; L355-A443 HydrophobicContact CD2-CB 4.34Å; L439-A443 VanDerWaalsContact O-CB 3.32Å; L439-A443 WeakPolarHBondContact O-CB 3.41Å; L439-A443 PolarHBondContact O-N 3Å
444D98.2Very high97.3Very high1 Ų122.3 Ų22.31%0.00511%0.107CC..SBendtrans-59.5-46.9172.6-63.5-40.4000111.9N25 R26 L28 K346 K352 T353 Y442N25-D444 PolarHBondContact N-O 3.46Å; R26-D444 HydrophobicContact CB-CB 4.33Å; R26-D444 VanDerWaalsContact CD-OD1 3.26Å; R26-D444 WeakPolarHBondContact CD-OD1 3.35Å; R26-D444 IonicContact CZ-OD1 2.69Å; R26-D444 PolarHBondContact N-O 2.85Å; R26-D444 IonicContact NE-OD1 2.75Å; R26-D444 PolarHBondContact NE-OD1 3.24Å; L28-D444 HydrophobicContact CD1-CB 4.34Å; K346-D444 IonicContact NZ-OD1 2.7Å; K346-D444 PolarHBondContact NZ-OD1 3.41Å; K346-D444 IonicContact NZ-OD2 2.9Å; K346-D444 PolarHBondContact NZ-OD2 2.97Å; K352-D444 WeakPolarHBondContact CA-OD2 3.43Å; K352-D444 WeakPolarHBondContact CD-OD2 3.45Å; T353-D444 PolarHBondContact N-OD2 2.79Å; T353-D444 WeakPolarHBondContact O-CB 3.46Å; T353-D444 PolarHBondContact O-N 3.09Å; T353-D444 PolarHBondContact OG1-N 3.18Å; Y442-D444 PolarHBondContact O-N 3Å
445L98.6Very high97.3Very high0 Ų025.4 Ų25.40%012%0.121CC..EExtended strand (participates in β ladder)trans-121.9154175.2-56.7177.9000109.8V22 F23 V24 L28 T353 F354 L355 F462V22-L445 HydrophobicContact CG1-CB 4Å; V22-L445 HydrophobicContact CG1-CD1 4.24Å; V22-L445 HydrophobicContact CG1-CD2 4.23Å; V22-L445 HydrophobicContact CG1-CG 4.39Å; F23-L445 WeakPolarHBondContact O-CA 3.27Å; V24-L445 HydrophobicContact CB-CD2 4.22Å; V24-L445 HydrophobicContact CG1-CD2 3.93Å; V24-L445 HydrophobicContact CG2-CD2 3.94Å; L28-L445 HydrophobicContact CD1-CD1 4.1Å; L28-L445 HydrophobicContact CD1-CG 4.3Å; L28-L445 HydrophobicContact CD2-CD1 4.28Å; T353-L445 PolarHBondContact O-N 3.38Å; F354-L445 CarbonylContact C-O 3.54Å; F354-L445 WeakPolarHBondContact CA-O 3.44Å; F354-L445 HydrophobicContact CB-CB 4.44Å; F354-L445 HydrophobicContact CD2-CB 3.71Å; F354-L445 HydrophobicContact CD2-CD1 4.09Å; F354-L445 HydrophobicContact CE2-CB 4.31Å; F354-L445 HydrophobicContact CG-CB 4.23Å; L355-L445 PolarHBondContact N-O 2.89Å; L445-F462 HydrophobicContact CD1-CD2 3.76Å; L445-F462 HydrophobicContact CD1-CE2 3.84Å; L445-F462 HydrophobicContact CD1-CG 4.37Å; L445-F462 HydrophobicContact CD2-CB 3.82Å; L445-F462 HydrophobicContact CD2-CD1 4.18Å; L445-F462 HydrophobicContact CD2-CD2 3.94Å; L445-F462 HydrophobicContact CD2-CG 3.71Å
446Y98.5Very high97.3Very high44 Ų4426.1 Ų26.117%0.17312%0.124CC..EExtended strand (participates in β ladder)trans-151155.9169.270.9-80.2000111.9F23 N25 L355 L360 L439F23-Y446 HydrophobicContact CB-CD1 3.71Å; F23-Y446 HydrophobicContact CB-CD2 4.1Å; F23-Y446 HydrophobicContact CB-CE1 3.25Å; F23-Y446 HydrophobicContact CB-CE2 3.67Å; F23-Y446 HydrophobicContact CB-CG 4.11Å; F23-Y446 HydrophobicContact CD2-CD2 4.19Å; F23-Y446 AromaticContact CD2-CE2 3.77Å; F23-Y446 HydrophobicContact CD2-CE2 3.77Å; F23-Y446 HydrophobicContact CG-CD2 4.48Å; F23-Y446 HydrophobicContact CG-CE1 4.24Å; F23-Y446 AromaticContact CG-CE2 3.84Å; F23-Y446 HydrophobicContact CG-CE2 3.84Å; F23-Y446 AromaticContact CG-CZ 3.69Å; F23-Y446 PolarHBondContact N-O 3.34Å; F23-Y446 PolarHBondContact O-N 3.04Å; N25-Y446 WeakPolarHBondContact ND2-CD1 2.92Å; L355-Y446 WeakPolarHBondContact O-CA 3.42Å; L355-Y446 WeakPolarHBondContact O-CB 3.2Å; L360-Y446 HydrophobicContact CD2-CD2 3.89Å; L360-Y446 HydrophobicContact CD2-CE2 3.84Å; L439-Y446 HydrophobicContact CD1-CD2 4.18Å; L439-Y446 HydrophobicContact CD1-CG 4.37Å; L439-Y446 HydrophobicContact CD2-CD1 3.68Å; L439-Y446 HydrophobicContact CD2-CD2 4.23Å; L439-Y446 HydrophobicContact CD2-CE1 3.78Å; L439-Y446 HydrophobicContact CD2-CE2 4.35Å; L439-Y446 HydrophobicContact CD2-CG 3.91Å; L439-Y446 HydrophobicContact CG-CG 4.39Å
447S98.3Very high97.2Very high1 Ų129.1 Ų29.11%0.00714%0.142CC..EExtended strand (participates in β ladder)trans-162.4171.4175.9-1630000111K21 L355 V357 T449 N452K21-S447 PolarHBondContact O-OG 3.33Å; L355-S447 PolarHBondContact O-N 3.45Å; L355-S447 VanDerWaalsContact O-N 3.09Å; V357-S447 PolarHBondContact N-O 3.42Å; S447-T449 VanDerWaalsContact C-N 3.26Å; S447-T449 PolarHBondContact O-N 3.39Å; S447-N452 PolarHBondContact OG-ND2 3.42Å
448S96.6Very high97.1Very high10 Ų1029.7 Ų29.77%0.0714%0.141CC..SBendtrans-66.4-29.8173.353.80000112.9V357 T361V357-S448 WeakPolarHBondContact O-CA 3.33Å; T361-S448 VanDerWaalsContact OG1-CB 3.27Å; T361-S448 WeakPolarHBondContact OG1-CB 3.14Å
449T97.1Very high97Very high35 Ų3534 Ų3422%0.21516%0.164CC..  trans-146.8149.1178.9176.70000111S447 I451 N452S447-T449 VanDerWaalsContact C-N 3.26Å; S447-T449 PolarHBondContact O-N 3.39Å; T449-I451 HydrophobicContact CG2-CB 4Å; T449-I451 PolarHBondContact O-N 3.14Å; T449-I451 WeakPolarHBondContact OG1-CG1 3.1Å; T449-I451 PolarHBondContact OG1-N 2.9Å; T449-N452 PolarHBondContact O-N 3.01Å
450C96.8Very high97Very high1 Ų136.4 Ų36.41%0.00717%0.173CC..G310 helixtrans-65.4-21171.864.80000112.6F38 T43 I334 V356 N452 L453F38-C450 HydrophobicContact CE1-CB 4.35Å; T43-C450 PolarHBondContact O-SG 3.47Å; I334-C450 HydrophobicContact CG2-CB 3.69Å; V356-C450 HydrophobicContact CG2-CB 4.12Å; C450-N452 PolarHBondContact O-N 3.09Å; C450-N452 VanDerWaalsContact O-N 3.16Å; C450-L453 WeakPolarHBondContact O-CB 3.38Å; C450-L453 PolarHBondContact O-N 2.63Å; C450-L453 VanDerWaalsContact O-N 3.16Å
451I97.2Very high97Very high8 Ų836.8 Ų36.84%0.04118%0.175CC..G310 helixtrans-60.5-25.5178.8-61.5-58.5000112.6N218 I219 L222 T449 L453 L454N218-I451 HydrophobicContact CB-CD1 4.48Å; N218-I451 HydrophobicContact CB-CG2 3.83Å; I219-I451 HydrophobicContact CB-CD1 4.13Å; I219-I451 HydrophobicContact CG1-CD1 3.49Å; I219-I451 VanDerWaalsContact CG1-CD1 3.49Å; I219-I451 HydrophobicContact CG1-CG1 4.26Å; L222-I451 HydrophobicContact CD2-CD1 4.06Å; T449-I451 HydrophobicContact CG2-CB 4Å; T449-I451 PolarHBondContact O-N 3.14Å; T449-I451 WeakPolarHBondContact OG1-CG1 3.1Å; T449-I451 PolarHBondContact OG1-N 2.9Å; I451-L453 PolarHBondContact O-N 3.01Å; I451-L454 WeakPolarHBondContact O-CB 3.5Å; I451-L454 PolarHBondContact O-N 2.87Å
452N97.4Very high97.1Very high7 Ų729.3 Ų29.34%0.03715%0.148CC..G310 helixtrans-62.8-18.3179.4-72.6-15.2000113.5E19 K20 V22 S447 T449 C450 L454 H455 Y456E19-N452 PolarHBondContact O-ND2 2.93Å; E19-N452 PolarHBondContact O-OD1 2.72Å; K20-N452 WeakPolarHBondContact CA-OD1 3.27Å; V22-N452 HydrophobicContact CG2-CB 3.86Å; S447-N452 PolarHBondContact OG-ND2 3.42Å; T449-N452 PolarHBondContact O-N 3.01Å; C450-N452 PolarHBondContact O-N 3.09Å; C450-N452 VanDerWaalsContact O-N 3.16Å; N452-L454 PolarHBondContact O-N 3.07Å; N452-H455 PolarHBondContact O-N 3.33Å; N452-Y456 VanDerWaalsContact O-CD2 3.25Å; N452-Y456 WeakPolarHBondContact O-CD2 3.47Å; N452-Y456 WeakPolarHBondContact O-CE2 3.21Å
453L97.1Very high97Very high4 Ų434.9 Ų34.92%0.02118%0.176CC..G310 helixtrans-59.2-27.7168.9-71.8171.7000112.7V22 L222 F354 C450 I451 H455 Y456 F462V22-L453 HydrophobicContact CG2-CD2 4.3Å; L222-L453 HydrophobicContact CD1-CB 4.09Å; F354-L453 HydrophobicContact CD2-CD1 4.18Å; F354-L453 HydrophobicContact CD2-CD2 4.1Å; F354-L453 HydrophobicContact CD2-CG 4.25Å; F354-L453 HydrophobicContact CE2-CD1 4.09Å; F354-L453 HydrophobicContact CE2-CD2 3.73Å; F354-L453 HydrophobicContact CE2-CG 3.73Å; F354-L453 HydrophobicContact CZ-CG 4.41Å; C450-L453 WeakPolarHBondContact O-CB 3.38Å; C450-L453 PolarHBondContact O-N 2.63Å; C450-L453 VanDerWaalsContact O-N 3.16Å; I451-L453 PolarHBondContact O-N 3.01Å; L453-H455 PolarHBondContact O-N 3.42Å; L453-H455 VanDerWaalsContact O-N 3.1Å; L453-Y456 PolarHBondContact O-N 3.38Å; L453-Y456 VanDerWaalsContact O-N 3.11Å; L453-F462 HydrophobicContact CD2-CZ 4.48Å
454L96.3Very high96.9Very high27 Ų2735.9 Ų35.914%0.14118%0.184CC..G310 helixtrans-62-20.1179.1-169.863000113.1N218 V221 L222 R225 I451 N452 Y456N218-L454 HydrophobicContact CB-CD2 3.96Å; V221-L454 HydrophobicContact CG1-CD1 4.15Å; V221-L454 HydrophobicContact CG1-CD2 4.47Å; L222-L454 HydrophobicContact CD1-CB 4.35Å; L222-L454 HydrophobicContact CD1-CD1 4.46Å; R225-L454 VanDerWaalsContact NH1-CD1 3.28Å; I451-L454 WeakPolarHBondContact O-CB 3.5Å; I451-L454 PolarHBondContact O-N 2.87Å; N452-L454 PolarHBondContact O-N 3.07Å; L454-Y456 VanDerWaalsContact C-N 3.3Å
455H96.5Very high96.5Very high72 Ų7241 Ų4133%0.33322%0.218SC..G310 helixtrans-88.66.7-180-56.5-50.8000113.8R16 N452 L453R16-H455 PolarHBondContact NH1-O 3.3Å; R16-H455 PolarHBondContact NH2-O 3.01Å; N452-H455 PolarHBondContact O-N 3.33Å; L453-H455 PolarHBondContact O-N 3.42Å; L453-H455 VanDerWaalsContact O-N 3.1Å
456Y96.9Very high96Very high19 Ų1946.5 Ų46.58%0.07525%0.253CS..SBendtrans-127.5140.3-180-61.4-95.9000109.7V22 N452 L453 L454 Y460 F462V22-Y456 HydrophobicContact CB-CE2 3.94Å; V22-Y456 HydrophobicContact CG2-CD2 4.17Å; V22-Y456 HydrophobicContact CG2-CE2 3.71Å; V22-Y456 PolarHBondContact N-OH 3.48Å; V22-Y456 VanDerWaalsContact N-OH 3.11Å; N452-Y456 VanDerWaalsContact O-CD2 3.25Å; N452-Y456 WeakPolarHBondContact O-CD2 3.47Å; N452-Y456 WeakPolarHBondContact O-CE2 3.21Å; L453-Y456 PolarHBondContact O-N 3.38Å; L453-Y456 VanDerWaalsContact O-N 3.11Å; L454-Y456 VanDerWaalsContact C-N 3.3Å; Y456-Y460 AromaticContact CD1-CD1 3.59Å; Y456-Y460 HydrophobicContact CD1-CD1 3.59Å; Y456-Y460 AromaticContact CD1-CD2 3.98Å; Y456-Y460 HydrophobicContact CD1-CD2 3.98Å; Y456-Y460 AromaticContact CD1-CE1 3.52Å; Y456-Y460 HydrophobicContact CD1-CE1 3.52Å; Y456-Y460 AromaticContact CD1-CE2 3.92Å; Y456-Y460 HydrophobicContact CD1-CE2 3.92Å; Y456-Y460 AromaticContact CD1-CG 3.83Å; Y456-Y460 HydrophobicContact CD1-CG 3.83Å; Y456-Y460 AromaticContact CD1-CZ 3.68Å; Y456-Y460 HydrophobicContact CE1-CD1 4.26Å; Y456-Y460 AromaticContact CE1-CE1 3.72Å; Y456-Y460 HydrophobicContact CE1-CE1 3.72Å; Y456-Y460 HydrophobicContact CE1-CE2 4.38Å; Y456-Y460 AromaticContact CE1-CZ 3.8Å; Y456-Y460 HydrophobicContact CG-CD1 4.42Å; Y456-F462 AromaticContact CD1-CE1 3.76Å; Y456-F462 HydrophobicContact CD1-CE1 3.76Å; Y456-F462 AromaticContact CD1-CZ 3.87Å; Y456-F462 HydrophobicContact CD1-CZ 3.87Å; Y456-F462 HydrophobicContact CD2-CE1 4.46Å; Y456-F462 HydrophobicContact CD2-CZ 4.16Å; Y456-F462 AromaticContact CE1-CE1 3.63Å; Y456-F462 HydrophobicContact CE1-CE1 3.63Å; Y456-F462 HydrophobicContact CE1-CZ 4.16Å; Y456-F462 HydrophobicContact CE2-CE1 4.39Å; Y456-F462 HydrophobicContact CE2-CZ 4.48Å; Y456-F462 HydrophobicContact CG-CE1 4.17Å; Y456-F462 AromaticContact CG-CZ 3.85Å; Y456-F462 HydrophobicContact CG-CZ 3.85Å; Y456-F462 AromaticContact CZ-CE1 3.96Å
457P96.4Very high95.6Very high68 Ų6851 Ų5144%0.44229%0.285SS..  trans-70.7153.2172.532-35.8000110.5N459 Y460P457-N459 WeakPolarHBondContact CB-OD1 3.47Å; P457-N459 WeakPolarHBondContact CG-OD1 3.49Å; P457-N459 PolarHBondContact O-N 3.3Å; P457-N459 VanDerWaalsContact O-N 3.12Å; P457-Y460 HydrophobicContact CG-CD2 4.22Å; P457-Y460 WeakPolarHBondContact O-CB 3.21Å; P457-Y460 PolarHBondContact O-N 2.98Å
458F94.4Very high95.3Very high48 Ų4854.4 Ų54.421%0.21130%0.303CS..THydrogen-bonded Turntrans-71.9-3.5-178.8-66.4-63.1000115L30 E31 R225 I226 V229L30-F458 CarbonylContact C-O 3.32Å; L30-F458 WeakPolarHBondContact CB-O 3.31Å; E31-F458 WeakPolarHBondContact CA-O 3.5Å; E31-F458 PolarHBondContact N-O 3.32Å; R225-F458 HydrophobicContact CB-CE2 3.81Å; R225-F458 HydrophobicContact CB-CZ 4.01Å; R225-F458 VanDerWaalsContact O-CE2 3.26Å; R225-F458 WeakPolarHBondContact O-CE2 3.49Å; I226-F458 HydrophobicContact CB-CZ 4.26Å; I226-F458 HydrophobicContact CG1-CE1 3.6Å; I226-F458 HydrophobicContact CG1-CZ 3.54Å; V229-F458 HydrophobicContact CG1-CD2 4.23Å; V229-F458 HydrophobicContact CG2-CB 4.16Å; V229-F458 HydrophobicContact CG2-CD1 4.27Å; V229-F458 HydrophobicContact CG2-CD2 3.7Å; V229-F458 HydrophobicContact CG2-CE2 4.1Å; V229-F458 HydrophobicContact CG2-CG 3.8Å
459N95.2Very high95.1Very high106 Ų10659.1 Ų59.157%0.56733%0.325SS*.THydrogen-bonded Turntrans-99.413.416767-12000112.8P457P457-N459 WeakPolarHBondContact CB-OD1 3.47Å; P457-N459 WeakPolarHBondContact CG-OD1 3.49Å; P457-N459 PolarHBondContact O-N 3.3Å; P457-N459 VanDerWaalsContact O-N 3.12Å
460Y97.4Very high94.8Very high58 Ų5862.5 Ų62.523%0.22735%0.348CS..  trans-67.8139.1-179.6-165.6-100.5000112M13 L30 Y456 P457 F462M13-Y460 VanDerWaalsContact CE-OH 3.29Å; M13-Y460 WeakPolarHBondContact CE-OH 3.37Å; L30-Y460 PolarHBondContact N-O 2.92Å; Y456-Y460 AromaticContact CD1-CD1 3.59Å; Y456-Y460 HydrophobicContact CD1-CD1 3.59Å; Y456-Y460 AromaticContact CD1-CD2 3.98Å; Y456-Y460 HydrophobicContact CD1-CD2 3.98Å; Y456-Y460 AromaticContact CD1-CE1 3.52Å; Y456-Y460 HydrophobicContact CD1-CE1 3.52Å; Y456-Y460 AromaticContact CD1-CE2 3.92Å; Y456-Y460 HydrophobicContact CD1-CE2 3.92Å; Y456-Y460 AromaticContact CD1-CG 3.83Å; Y456-Y460 HydrophobicContact CD1-CG 3.83Å; Y456-Y460 AromaticContact CD1-CZ 3.68Å; Y456-Y460 HydrophobicContact CE1-CD1 4.26Å; Y456-Y460 AromaticContact CE1-CE1 3.72Å; Y456-Y460 HydrophobicContact CE1-CE1 3.72Å; Y456-Y460 HydrophobicContact CE1-CE2 4.38Å; Y456-Y460 AromaticContact CE1-CZ 3.8Å; Y456-Y460 HydrophobicContact CG-CD1 4.42Å; P457-Y460 HydrophobicContact CG-CD2 4.22Å; P457-Y460 WeakPolarHBondContact O-CB 3.21Å; P457-Y460 PolarHBondContact O-N 2.98Å; Y460-F462 AromaticContact CD1-CD1 3.76Å; Y460-F462 HydrophobicContact CD1-CD1 3.76Å; Y460-F462 AromaticContact CD1-CD2 4Å; Y460-F462 HydrophobicContact CD1-CD2 4Å; Y460-F462 AromaticContact CD1-CE1 3.73Å; Y460-F462 HydrophobicContact CD1-CE1 3.73Å; Y460-F462 AromaticContact CD1-CE2 3.99Å; Y460-F462 HydrophobicContact CD1-CE2 3.99Å; Y460-F462 AromaticContact CD1-CG 3.89Å; Y460-F462 HydrophobicContact CD1-CG 3.89Å; Y460-F462 AromaticContact CD1-CZ 3.86Å; Y460-F462 HydrophobicContact CD1-CZ 3.86Å; Y460-F462 AromaticContact CE1-CD1 3.52Å; Y460-F462 HydrophobicContact CE1-CD1 3.52Å; Y460-F462 AromaticContact CE1-CE1 3.64Å; Y460-F462 HydrophobicContact CE1-CE1 3.64Å; Y460-F462 HydrophobicContact CE1-CG 4.01Å; Y460-F462 HydrophobicContact CE1-CZ 4.24Å
461L97.1Very high94.6Very high80 Ų8068.8 Ų68.842%0.41938%0.377SS..EExtended strand (participates in β ladder)trans-101.6106170.8175.963.9000109.3T29 M463T29-L461 HydrophobicContact CG2-CD1 4.46Å; T29-L461 VanDerWaalsContact OG1-CD1 3.25Å; T29-L461 WeakPolarHBondContact OG1-CD1 3.48Å; L461-M463 HydrophobicContact CD2-CG 3.84Å; L461-M463 HydrophobicContact CD2-SD 3.85Å; L461-M463 HydrophobicContact CG-CG 3.69Å; L461-M463 HydrophobicContact CG-SD 4.36Å
462F97.5Very high94.2Very high4 Ų472.6 Ų72.62%0.01839%0.394CS..EExtended strand (participates in β ladder)trans-72.9125.2165.9-69.6-72.6000109V22 V24 S27 L28 L30 L445 L453 Y456 Y460V22-F462 HydrophobicContact CB-CE1 3.72Å; V22-F462 HydrophobicContact CB-CZ 3.96Å; V22-F462 HydrophobicContact CG1-CD1 4.38Å; V22-F462 HydrophobicContact CG1-CE1 3.75Å; V22-F462 HydrophobicContact CG1-CZ 3.86Å; V22-F462 HydrophobicContact CG2-CZ 4.41Å; V24-F462 HydrophobicContact CB-CB 4.48Å; V24-F462 HydrophobicContact CG1-CB 3.87Å; V24-F462 HydrophobicContact CG2-CB 3.72Å; V24-F462 HydrophobicContact CG2-CD1 3.51Å; V24-F462 HydrophobicContact CG2-CG 3.98Å; S27-F462 CarbonylContact C-O 3.58Å; S27-F462 WeakPolarHBondContact CA-O 3.37Å; S27-F462 WeakPolarHBondContact CB-O 3.31Å; L28-F462 HydrophobicContact CB-CB 4.47Å; L28-F462 HydrophobicContact CD2-CD2 4.41Å; L28-F462 PolarHBondContact N-O 2.98Å; L28-F462 WeakPolarHBondContact O-CB 3.39Å; L28-F462 PolarHBondContact O-N 3.21Å; L30-F462 HydrophobicContact CD1-CE2 3.81Å; L30-F462 HydrophobicContact CD2-CD2 4.49Å; L30-F462 HydrophobicContact CD2-CE2 4.04Å; L30-F462 HydrophobicContact CG-CD2 4.23Å; L30-F462 HydrophobicContact CG-CE2 3.82Å; L445-F462 HydrophobicContact CD1-CD2 3.76Å; L445-F462 HydrophobicContact CD1-CE2 3.84Å; L445-F462 HydrophobicContact CD1-CG 4.37Å; L445-F462 HydrophobicContact CD2-CB 3.82Å; L445-F462 HydrophobicContact CD2-CD1 4.18Å; L445-F462 HydrophobicContact CD2-CD2 3.94Å; L445-F462 HydrophobicContact CD2-CG 3.71Å; L453-F462 HydrophobicContact CD2-CZ 4.48Å; Y456-F462 AromaticContact CD1-CE1 3.76Å; Y456-F462 HydrophobicContact CD1-CE1 3.76Å; Y456-F462 AromaticContact CD1-CZ 3.87Å; Y456-F462 HydrophobicContact CD1-CZ 3.87Å; Y456-F462 HydrophobicContact CD2-CE1 4.46Å; Y456-F462 HydrophobicContact CD2-CZ 4.16Å; Y456-F462 AromaticContact CE1-CE1 3.63Å; Y456-F462 HydrophobicContact CE1-CE1 3.63Å; Y456-F462 HydrophobicContact CE1-CZ 4.16Å; Y456-F462 HydrophobicContact CE2-CE1 4.39Å; Y456-F462 HydrophobicContact CE2-CZ 4.48Å; Y456-F462 HydrophobicContact CG-CE1 4.17Å; Y456-F462 AromaticContact CG-CZ 3.85Å; Y456-F462 HydrophobicContact CG-CZ 3.85Å; Y456-F462 AromaticContact CZ-CE1 3.96Å; Y460-F462 AromaticContact CD1-CD1 3.76Å; Y460-F462 HydrophobicContact CD1-CD1 3.76Å; Y460-F462 AromaticContact CD1-CD2 4Å; Y460-F462 HydrophobicContact CD1-CD2 4Å; Y460-F462 AromaticContact CD1-CE1 3.73Å; Y460-F462 HydrophobicContact CD1-CE1 3.73Å; Y460-F462 AromaticContact CD1-CE2 3.99Å; Y460-F462 HydrophobicContact CD1-CE2 3.99Å; Y460-F462 AromaticContact CD1-CG 3.89Å; Y460-F462 HydrophobicContact CD1-CG 3.89Å; Y460-F462 AromaticContact CD1-CZ 3.86Å; Y460-F462 HydrophobicContact CD1-CZ 3.86Å; Y460-F462 AromaticContact CE1-CD1 3.52Å; Y460-F462 HydrophobicContact CE1-CD1 3.52Å; Y460-F462 AromaticContact CE1-CE1 3.64Å; Y460-F462 HydrophobicContact CE1-CE1 3.64Å; Y460-F462 HydrophobicContact CE1-CG 4.01Å; Y460-F462 HydrophobicContact CE1-CZ 4.24Å
463M96.2Very high93.6Very high139 Ų13974.1 Ų74.169%0.68541%0.408SS*.  trans-116.2127.5-179.6-63.7-163.5-64.700110.9L461L461-M463 HydrophobicContact CD2-CG 3.84Å; L461-M463 HydrophobicContact CD2-SD 3.85Å; L461-M463 HydrophobicContact CG-CG 3.69Å; L461-M463 HydrophobicContact CG-SD 4.36Å
464A94.4Very high92.6Very high22 Ų2278.5 Ų78.518%0.18244%0.435CS..PPolyproline II helixtrans-100.9146163.700000109.3V24 N25 S27V24-A464 HydrophobicContact CG1-CB 4.11Å; N25-A464 WeakPolarHBondContact O-CB 3.1Å; S27-A464 PolarHBondContact OG-N 2.87Å
465P89.9Confident90.7Very high109 Ų10981.6 Ų81.671%0.70846%0.459SS*.PPolyproline II helixtrans-61.7148.8172.327.3-33.7000110.6
466P89.1Confident88.8Confident115 Ų11584.1 Ų84.175%0.74747%0.471SS*.PPolyproline II helixtrans-61.9138.3173.626.8-33000110.1
467V90.6Very high86.5Confident138 Ų13887 Ų8784%0.83649%0.493SS*.PPolyproline II helixtrans-84.1120.9176.1-1790000108.2
468L90.2Very high83.7Confident72 Ų7288.2 Ų88.238%0.37750%0.504SS..PPolyproline II helixtrans-100.7138174.2-62.3179.5000110.1E472L468-E472 WeakPolarHBondContact CA-OE2 3.45Å; L468-E472 HydrophobicContact CB-CB 4.19Å; L468-E472 HydrophobicContact CD2-CB 4.23Å
469M93.1Very high81.1Confident109 Ų10989.7 Ų89.754%0.53753%0.525SS..PPolyproline II helixtrans-67.6153.1165.6-65.5-67.8-74.100109.5H471 E472 A473M469-H471 VanDerWaalsContact CB-CE1 3.47Å; M469-H471 WeakPolarHBondContact CB-CE1 3.47Å; M469-H471 PolarHBondContact O-N 3.45Å; M469-H471 VanDerWaalsContact O-N 3.08Å; M469-E472 HydrophobicContact CB-CG 4.17Å; M469-E472 PolarHBondContact N-OE2 3.1Å; M469-E472 WeakPolarHBondContact O-CB 3.49Å; M469-E472 PolarHBondContact O-N 2.79Å; M469-A473 PolarHBondContact O-N 2.97Å
470P91.4Very high78.2Confident106 Ų10691.7 Ų91.769%0.68854%0.535SS*.Hα-helixtrans-53.5-36.9-176.9-29.836000114.3E472 A473 V474P470-E472 VanDerWaalsContact C-N 3.32Å; P470-E472 PolarHBondContact O-N 3.4Å; P470-A473 PolarHBondContact O-N 3.33Å; P470-V474 WeakPolarHBondContact O-CG2 3.5Å
471H91.4Very high75.1Confident133 Ų13395.6 Ų95.662%0.61656%0.559SS**Hα-helixtrans-72.1-22.8179.168.1-88000113.9M469M469-H471 VanDerWaalsContact CB-CE1 3.47Å; M469-H471 WeakPolarHBondContact CB-CE1 3.47Å; M469-H471 PolarHBondContact O-N 3.45Å; M469-H471 VanDerWaalsContact O-N 3.08Å
472E89.6Confident71.8Confident88 Ų8897 Ų9741%0.41157%0.572SS.*Hα-helixtrans-78.9-25175.7-60173143.600111.3L468 M469 P470L468-E472 WeakPolarHBondContact CA-OE2 3.45Å; L468-E472 HydrophobicContact CB-CB 4.19Å; L468-E472 HydrophobicContact CD2-CB 4.23Å; M469-E472 HydrophobicContact CB-CG 4.17Å; M469-E472 PolarHBondContact N-OE2 3.1Å; M469-E472 WeakPolarHBondContact O-CB 3.49Å; M469-E472 PolarHBondContact O-N 2.79Å; P470-E472 VanDerWaalsContact C-N 3.32Å; P470-E472 PolarHBondContact O-N 3.4Å
473A84.5Confident68.5Low40 Ų40101.9 Ų101.933%0.33161%0.607SS.*Hα-helixtrans-80.6-21.5179.600000113.7M469 P470 S475 Q476 S477M469-A473 PolarHBondContact O-N 2.97Å; P470-A473 PolarHBondContact O-N 3.33Å; A473-S475 PolarHBondContact O-N 2.87Å; A473-Q476 PolarHBondContact O-N 2.93Å; A473-S477 PolarHBondContact O-N 3.48Å
474V75.8Confident65.3Low95 Ų95101.4 Ų101.458%0.57661%0.612SS**Hα-helixtrans-58-37.8-178.3-179.90000111.9P470 Q476 S477P470-V474 WeakPolarHBondContact O-CG2 3.5Å; V474-Q476 VanDerWaalsContact C-N 3.27Å; V474-Q476 PolarHBondContact O-N 3.16Å; V474-S477 PolarHBondContact O-OG 2.96Å
475S58.2Low62.2Low93 Ų93109.2 Ų109.265%0.6565%0.645SS**Hα-helixtrans-72.7-16.2179.8-53.50000114A473 S478A473-S475 PolarHBondContact O-N 2.87Å; S475-S478 PolarHBondContact O-OG 3.25Å
476Q55.6Low59.3Low125 Ų125112.4 Ų112.458%0.58465%0.651SS**Hα-helixtrans-88.3-33.9177.4-66.8-176.7-4.300111.7A473 V474 S478 A479A473-Q476 PolarHBondContact O-N 2.93Å; V474-Q476 VanDerWaalsContact C-N 3.27Å; V474-Q476 PolarHBondContact O-N 3.16Å; Q476-S478 PolarHBondContact O-N 2.97Å; Q476-A479 PolarHBondContact O-N 2.65Å
477S47.6Very low56.5Low78 Ų78114.9 Ų114.955%0.54566%0.658SS.*Hα-helixtrans-67-18.9178.242.30000114.9A473 V474 A479A473-S477 PolarHBondContact O-N 3.48Å; V474-S477 PolarHBondContact O-OG 2.96Å; S477-A479 VanDerWaalsContact C-N 3.35Å
478S39.6Very low53.7Low95 Ų95114 Ų11466%0.66465%0.652SS**THydrogen-bonded Turntrans-81.9-8.3176.950.90000114.4S475 Q476S475-S478 PolarHBondContact O-OG 3.25Å; Q476-S478 PolarHBondContact O-N 2.97Å
479A38.5Very low50.8Low79 Ų79117.2 Ų117.265%0.65367%0.67SS**SBendtrans-96.1-13.4-175.600000114.6Q476 S477Q476-A479 PolarHBondContact O-N 2.65Å; S477-A479 VanDerWaalsContact C-N 3.35Å
480D34.3Very low47.8Very low147 Ų147119.8 Ų119.879%0.78669%0.686SS**SBendtrans-121.527.9-170.8-78.6-28.3000114.7P482D480-P482 VanDerWaalsContact O-CD 3.28Å; D480-P482 WeakPolarHBondContact O-CD 3.39Å
481I31.8Very low44.9Very low141 Ų141122.8 Ų122.872%0.72369%0.69SS**  trans-100.9100.6164.3-52.8177.3000108S483I481-S483 PolarHBondContact O-N 3.29Å; I481-S483 VanDerWaalsContact O-N 3.14Å
482P29.2Very low42.1Very low108 Ų108126.1 Ų126.170%0.70170%0.703SS**  trans-66.8114.7162.618.7-12.8000107.1D480 T484D480-P482 VanDerWaalsContact O-CD 3.28Å; D480-P482 WeakPolarHBondContact O-CD 3.39Å; P482-T484 VanDerWaalsContact C-N 3.34Å; P482-T484 PolarHBondContact O-N 3.09Å
483S28.5Very low39.3Very low107 Ų107129.2 Ų129.275%0.74872%0.722SS**  trans-61.594.4167.251.90000109I481 E485I481-S483 PolarHBondContact O-N 3.29Å; I481-S483 VanDerWaalsContact O-N 3.14Å; S483-E485 VanDerWaalsContact C-N 3.31Å; S483-E485 PolarHBondContact O-N 2.89Å; S483-E485 VanDerWaalsContact O-N 3.08Å
484T28.9Very low36.8Very low130 Ų130131.3 Ų131.380%0.79874%0.739SS**  trans-7488.9162.616.80000108.2P482 Q486P482-T484 VanDerWaalsContact C-N 3.34Å; P482-T484 PolarHBondContact O-N 3.09Å; T484-Q486 PolarHBondContact O-N 3.26Å; T484-Q486 VanDerWaalsContact O-N 3.09Å
485E29Very low34.7Very low186 Ų186132.9 Ų132.987%0.86975%0.75SS**  trans-60.3108.3156.1-79.4-173.7159.300107.9S483 N487S483-E485 VanDerWaalsContact C-N 3.31Å; S483-E485 PolarHBondContact O-N 2.89Å; S483-E485 VanDerWaalsContact O-N 3.08Å; E485-N487 PolarHBondContact O-N 3.01Å
486Q29.6Very low33.3Very low176 Ų176136.4 Ų136.482%0.82276%0.761SS**  trans-69.6108.7170-79.9-179.1-31.500109.3T484 V488T484-Q486 PolarHBondContact O-N 3.26Å; T484-Q486 VanDerWaalsContact O-N 3.09Å; Q486-V488 PolarHBondContact O-N 2.73Å
487N29.9Very low32.3Very low167 Ų167136.1 Ų136.189%0.89377%0.772SS**  trans-57110.2153.5-89.4-37.4000109.2E485E485-N487 PolarHBondContact O-N 3.01Å
488V31.2Very low31.5Very low119 Ų119141.6 Ų141.672%0.72181%0.81SS**  trans-108.6108.7162-178.10000107.8Q486 N490Q486-V488 PolarHBondContact O-N 2.73Å; V488-N490 PolarHBondContact O-N 3.42Å
489N29.4Very low31.1Very low140 Ų140144 Ų14475%0.74982%0.817SS**  trans-47.9126.7168-80.5-29.3000111.5
490N30.1Very low30.7Very low162 Ų162147.4 Ų147.487%0.86683%0.826SS**  trans-106.499154-92.8-26000108.5V488 K492V488-N490 PolarHBondContact O-N 3.42Å; N490-K492 PolarHBondContact O-N 3.47Å
491H31Very low30.5Very low169 Ų169147.4 Ų147.478%0.78283%0.828SS**  trans-68.7119.2156-97.6-72.2000108.4
492K31.5Very low30.5Very low204 Ų204147.8 Ų147.889%0.88783%0.834SS**  trans-130.1121.2148.5-86.5-172175.8179.60108.2N490N490-K492 PolarHBondContact O-N 3.47Å
493D31.5Very low30.6Very low152 Ų152150.3 Ų150.381%0.81384%0.843SS**  trans-53.1147.5170.7-66.1-54.5000112.7
494A30.9Very low30.7Very low84 Ų84153.1 Ų153.169%0.69485%0.849SS**  148.9107.8118.700000111
495T32.3Very low30.8Very low129 Ų129154.8 Ų154.879%0.79185%0.853SS**  trans36117.2134.547.70000118.7
496N29.5Very low31Very low167 Ų167152.4 Ų152.489%0.89385%0.851SS**  trans-147.3136.5135-107.6-16.9000112.6
497C33.3Very low31.1Very low119 Ų119150.4 Ų150.480%0.80485%0.854SS**  trans-32.8138.6175.1-63.80000116.9
498S32.3Very low31.2Very low193 Ų193148.9 Ų148.9100%1.3585%0.85SS**  -175.7091.550.90000110.7

Retrieved 498 of 498 residues in 290.8 ms (Link to these results)